Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 31.5;Distal tubular cells: 45.0;Hepatocytes: 77.9;Proximal enterocytes: 33.7;Proximal tubular cells: 151.1" "Group enriched" "Detected in many" 5 "liver cancer: 16.7;renal cancer: 5.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 7 "monocytes: 3.4" "Cell line enriched" "Detected in some" 8 "Hep G2: 68.4" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA038105: AB_2675835" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "prognostic favorable (3.82e-4)" "unprognostic (6.54e-3)" "unprognostic (3.64e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-3)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.41e-1)" 5.6 3.6 0.7 0.3 0.7 0.7 3.8 0.7 1.1 1.0 0.8 5.7 13.2 0.3 0.6 0.3 1.5 2.9 2.6 0.7 0.7 27.4 134.2 7.4 0.0 0.8 0.9 1.0 17.2 2.1 0.9 0.2 0.8 2.9 2.8 0.3 12.7 1.0 4.6 0.4 7.9 0.3 0.7 0.7 6.4 0.4 0.8 0.0 5.6 0.1 0.0 0.4 0.7 0.7 0.0 1.5 0.7 0.0 0.0 0.8 1.8 0.0 0.4 1.0 1.6 7.1 2.3 0.0 0.8 0.0 0.2 0.0 0.7 0.1 0.6 0.0 0.7 1.8 0.2 68.4 0.4 0.0 0.0 2.7 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.0 2.3 0.0 0.1 1.0 0.0 0.8 0.1 0.3 8.4 5.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.4 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.7 0.7 0.7 1.1 0.7 0.7 0.8 0.9 0.8 0.7 0.8 0.7 0.3 28.9 31.5 2.9 1.9 0.1 0.5 3.2 0.0 1.0 4.3 3.6 3.3 18.6 8.7 9.2 0.0 0.0 0.0 13.7 45.0 2.2 0.5 4.8 1.0 0.8 3.0 2.7 1.0 7.9 0.0 1.7 13.3 1.0 1.3 1.9 1.8 77.9 1.0 0.0 1.1 10.9 0.0 3.5 0.0 0.7 1.5 1.8 1.8 3.7 3.1 1.5 0.0 1.0 0.4 2.2 8.1 5.7 0.3 2.0 33.7 151.1 25.4 0.6 0.0 0.3 1.2 0.4 0.3 0.2 0.9 0.0 1.4 1.8 11.9 0.7 AC002996.1 ENSG00000257767 "Novel protein" 12 111753890-111791418 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 64.3;brain: 46.2;skeletal muscle: 37.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 88.5;myeloid DC: 88.0" "Group enriched" "Detected in many" 5 "dendritic cells: 88.0;monocytes: 88.5" "Cell line enhanced" "Detected in many" "BEWO: 9.1;EFO-21: 17.4;SK-BR-3: 8.7" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "unprognostic (4.89e-1)" "unprognostic (1.20e-1)" 64.3 16.5 24.4 2.9 25.1 0.3 6.5 23.2 18.0 4.1 6.5 11.7 9.7 7.5 0.0 5.8 7.2 0.1 14.1 15.2 25.4 7.7 24.0 9.9 0.7 31.1 34.5 5.3 1.4 0.0 2.4 0.8 25.0 1.8 0.2 1.6 5.7 1.6 37.8 5.4 6.5 0.0 33.7 1.9 17.7 1.3 46.2 0.1 3.6 0.0 0.2 7.6 4.2 39.4 3.5 0.0 0.0 0.9 0.0 1.4 9.1 1.0 4.2 1.6 0.8 0.0 2.0 0.0 17.4 1.9 1.5 3.2 0.0 0.7 0.1 0.5 0.4 0.0 2.6 0.0 0.0 0.4 0.0 0.0 1.9 1.9 0.0 0.0 4.5 0.0 1.6 0.2 0.7 0.0 0.0 0.7 5.1 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.6 4.7 0.0 8.7 0.1 0.1 6.3 3.4 0.0 0.0 2.0 0.3 0.0 1.3 2.1 5.4 2.5 0.1 0.0 2.1 88.5 18.7 0.3 38.6 0.7 3.2 0.0 0.2 88.0 1.1 0.2 0.1 3.7 1.0 13.0 23.7 0.4 53.5 24.4 25.1 23.2 18.0 15.2 25.4 31.1 34.5 25.0 33.7 46.2 39.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC004593.2 ENSG00000285162 "Chimerin 2" 7 29122340-29514667 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 3.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebellum: 3.3" "Group enriched" "Detected in some" 32 "classical monocyte: 4.1;intermediate monocyte: 3.4;myeloid DC: 4.3;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 42 "dendritic cells: 4.3;monocytes: 4.1" "Cell line enhanced" "Detected in some" "GAMG: 1.0;HaCaT: 1.1;U-266/84: 1.4" HPA019026 Uncertain "Nucleoplasm,Nuclear bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: U-266 - Nucleosome" Nucleoplasm "Nuclear bodies" "HPA019026: " 0.0 0.1 0.2 0.1 0.2 0.1 0.0 3.3 0.3 0.0 0.4 0.1 0.7 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.5 0.2 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.5 0.8 0.2 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.8 0.0 1.0 1.1 0.0 0.0 0.0 0.0 0.3 0.8 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.3 0.4 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.5 0.0 4.1 0.0 0.0 3.4 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 1.9 0.2 0.2 3.3 0.3 0.1 0.5 0.2 0.2 0.2 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC008763.3 ENSG00000269711 "Novel protein" 19 7678501-7682854 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "bone marrow: 22.6;intestine: 7.7;lung: 18.3;lymphoid tissue: 12.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.3;Club cells: 3.7;Fibroblasts: 1.3;granulocytes: 2.5;Macrophages: 1.3;Respiratory ciliated cells: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "classical monocyte: 202.7;neutrophil: 90.1" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "EFO-21: 12.8;HMC-1: 20.9;NB-4: 12.4;THP-1: 33.2;U-937: 24.6" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" 2.3 0.8 0.3 4.6 0.4 22.6 0.6 0.2 0.5 0.2 0.1 0.5 7.7 1.1 0.0 0.4 1.8 1.5 1.4 0.2 0.3 0.7 1.8 18.3 0.0 1.0 0.7 0.1 0.7 0.0 0.3 1.6 0.5 0.5 0.0 0.0 1.2 0.0 0.7 0.9 1.4 0.1 0.2 12.2 0.9 0.6 0.3 0.0 0.6 0.0 0.0 1.2 0.4 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 4.5 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 202.7 1.3 0.2 18.1 0.0 0.0 0.5 0.1 42.9 0.0 0.0 1.4 90.1 0.7 1.7 1.8 0.8 112.3 0.3 0.4 0.2 0.5 0.2 0.3 1.0 0.7 0.5 0.2 0.3 0.1 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 ACSM5 FLJ20581 ENSG00000183549 "Acyl-CoA synthetase medium chain family member 5" Q6NUN0 16 20409534-20441336 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 276.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 237.8" "Group enriched" "Detected in some" 7 "liver cancer: 20.5;renal cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 5.3;ASC TERT1: 11.5;HSkMC: 13.8;U-87 MG: 8.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041435 Uncertain Uncertain Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA041435: AB_10961121" "unprognostic (1.01e-1)" "unprognostic (1.61e-3)" "unprognostic (3.73e-2)" "unprognostic (1.98e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-2)" "unprognostic (1.84e-2)" "unprognostic (4.64e-3)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (2.15e-2)" "unprognostic (2.33e-1)" "unprognostic (5.11e-3)" "unprognostic (2.09e-2)" "unprognostic (3.85e-2)" "unprognostic (2.78e-2)" "unprognostic (1.57e-1)" 25.5 2.5 7.1 0.6 5.2 0.6 10.7 4.7 5.0 2.8 3.0 3.7 0.8 1.2 7.1 1.0 1.7 2.3 3.3 5.5 7.9 25.4 276.6 2.1 1.9 6.3 6.8 0.8 0.6 1.0 0.5 1.4 6.8 0.6 1.2 0.5 0.9 0.9 13.9 2.3 1.9 1.0 6.7 4.6 3.4 0.9 8.2 0.7 4.2 1.7 0.7 1.1 2.2 8.2 0.0 0.0 0.1 0.1 5.3 11.5 0.0 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 13.8 0.0 0.8 0.1 0.2 0.0 0.0 0.1 0.5 1.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 8.5 0.1 0.0 0.1 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 7.1 5.2 4.7 5.0 5.5 7.9 6.3 6.8 6.8 6.7 8.2 8.2 0.4 0.0 0.0 1.0 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.5 0.5 0.0 0.3 1.2 0.0 13.5 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 6.1 237.8 3.7 0.0 0.2 0.0 0.0 11.7 1.5 0.8 9.3 3.5 0.0 7.5 1.3 0.9 0.0 1.5 0.1 0.0 0.0 6.0 0.0 0.2 0.0 52.1 0.0 0.1 0.0 11.3 0.3 0.2 0.3 0.1 0.6 0.0 0.7 0.9 0.1 0.2 ADA2 "ADGF, CECR1, IDGFL" ENSG00000093072 "Adenosine deaminase 2" Q9NZK5 22 17178790-17258235 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 106.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.6;Glandular and luminal cells: 22.0;Hofbauer cells: 57.6;Macrophages: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.7;EFO-21: 21.4;HUVEC TERT2: 24.0;Karpas-707: 44.9;MOLT-4: 38.9;U-266/70: 23.8;U-937: 39.6" "Low region specificity" "Detected in all" HPA007888 Uncertain "Secreted to blood" NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA007888: AB_1078495" "unprognostic (1.03e-3)" "unprognostic (2.00e-3)" "unprognostic (6.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-2)" "unprognostic (7.01e-3)" "unprognostic (4.48e-2)" "unprognostic (3.09e-3)" "unprognostic (3.80e-2)" "prognostic favorable (9.26e-4)" "prognostic favorable (8.91e-4)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (4.86e-3)" "unprognostic (1.96e-2)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" 14.0 11.3 8.3 39.4 9.9 22.8 17.6 10.6 7.9 22.0 20.5 28.3 18.1 19.9 2.7 12.0 51.5 32.1 39.6 7.8 10.9 14.5 21.1 54.9 47.3 16.3 11.4 12.1 13.9 5.4 22.5 15.2 14.7 15.4 34.3 11.0 15.6 17.1 3.4 4.7 26.1 23.4 13.7 106.3 19.6 18.4 12.9 53.7 16.9 4.3 60.7 34.7 6.5 21.1 0.0 0.0 6.4 0.0 0.2 0.8 0.3 2.3 0.1 0.0 0.0 0.0 23.7 6.0 21.4 7.2 0.0 0.5 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.1 4.0 0.3 0.3 11.3 0.1 0.0 0.1 0.1 24.0 9.0 0.1 44.9 0.9 0.0 38.9 1.1 17.8 0.0 0.1 1.2 0.0 6.5 0.0 9.3 10.9 0.1 0.1 0.0 0.0 19.1 0.2 9.7 3.0 0.1 0.2 0.0 0.0 23.8 2.3 1.7 0.0 39.6 0.0 17.5 212.9 11.3 34.6 204.9 26.8 25.8 27.4 34.1 139.1 19.7 31.6 32.4 10.5 44.9 176.1 57.4 17.2 170.7 8.3 9.9 10.6 7.9 7.8 10.9 16.3 11.4 14.7 13.7 12.9 21.1 8.7 0.0 16.8 0.0 7.2 0.0 0.0 0.0 0.0 0.0 5.1 4.2 0.0 0.0 11.2 5.5 0.0 0.4 13.7 0.0 7.9 1.7 0.0 27.6 6.6 2.2 0.0 0.0 0.0 5.2 0.9 2.1 0.0 22.0 5.1 12.6 0.0 0.0 57.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 12.4 0.0 0.0 3.1 15.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.8 8.2 3.1 0.0 0.0 ADAM9 "CORD9, KIAA0021, MCMP, MDC9, Mltng" ENSG00000168615 "ADAM metallopeptidase domain 9" Q13443 8 38996754-39105445 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 179.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004000 Approved "Endoplasmic reticulum,Vesicles" "Secreted - unknown location" NA NA 740000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Endoplasmic reticulum" "HPA004000: AB_1844584" "prognostic unfavorable (1.14e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.32e-3)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.21e-6)" "unprognostic (5.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.83e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.80e-1)" "unprognostic (5.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-2)" 34.2 28.0 7.1 28.8 8.2 2.1 21.5 8.5 8.3 34.8 11.4 32.9 24.5 29.7 15.2 29.7 19.3 47.1 32.1 6.0 8.4 34.9 13.5 51.4 9.7 10.2 7.5 16.8 12.7 52.5 7.8 47.4 9.0 34.9 41.7 18.5 54.9 34.8 24.1 16.1 23.0 51.6 9.4 24.0 44.2 11.1 10.6 5.9 39.9 25.0 13.2 56.1 24.3 11.5 188.3 163.6 63.5 32.6 117.2 374.0 67.0 259.6 382.4 191.7 177.9 82.7 147.1 10.1 86.1 247.2 156.7 79.5 30.8 249.7 373.2 6.9 21.5 12.1 102.8 73.0 226.4 8.9 19.1 287.5 139.2 193.3 212.7 341.0 268.9 15.2 21.5 53.2 406.2 25.0 7.2 4.4 8.3 175.2 46.7 3.8 106.3 27.6 299.3 62.4 6.4 11.5 78.4 90.9 57.8 72.9 67.3 12.0 374.2 109.9 97.9 213.9 124.1 12.9 29.5 7.7 175.8 12.0 72.1 0.3 4.0 0.5 0.1 1.3 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.1 0.5 0.8 0.6 0.3 0.1 0.9 7.1 8.2 8.5 8.3 6.0 8.4 10.2 7.5 9.0 9.4 10.6 11.5 14.4 48.1 37.0 16.0 3.8 35.9 66.6 78.3 26.7 19.3 23.4 9.8 49.7 24.3 82.1 35.0 20.9 24.1 8.9 44.4 3.9 90.2 14.4 42.1 35.3 20.5 10.7 2.5 47.5 115.4 85.1 42.0 80.5 82.1 5.1 26.4 25.0 7.5 125.9 5.0 38.0 32.2 44.7 60.2 44.8 7.8 28.6 54.7 21.4 33.7 21.8 17.5 1.0 30.7 26.7 179.4 30.6 24.8 5.2 108.7 24.9 41.1 51.9 25.1 13.1 31.3 31.9 4.3 2.5 20.2 21.5 34.3 5.6 11.2 32.7 103.8 AGTRAP ATRAP ENSG00000177674 "Angiotensin II receptor associated protein" Q6RW13 1 11736084-11754802 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 446.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 196.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044120 Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Golgi apparatus" "HPA044120: AB_10960748" "unprognostic (1.08e-3)" "unprognostic (2.98e-3)" "unprognostic (6.10e-2)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (7.92e-3)" "prognostic unfavorable (6.57e-7)" "unprognostic (4.44e-2)" "unprognostic (7.96e-2)" "unprognostic (4.31e-2)" "unprognostic (1.61e-2)" "unprognostic (7.22e-2)" "unprognostic (1.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (2.33e-3)" "unprognostic (5.89e-2)" 44.1 50.3 26.6 30.2 28.5 132.3 44.3 27.1 32.4 34.6 44.0 29.3 11.2 24.7 47.7 53.6 48.3 25.2 37.0 24.5 30.5 65.8 29.5 62.3 23.4 37.3 28.8 26.9 67.3 25.7 31.2 22.0 31.3 79.1 9.3 3.4 39.0 21.0 54.3 38.8 25.7 20.3 28.4 83.4 33.7 24.7 31.8 11.3 40.8 12.4 13.3 43.9 43.3 31.1 55.9 66.7 16.7 36.9 27.5 34.9 30.5 28.6 49.0 34.8 30.2 42.0 129.7 5.4 126.7 35.4 87.3 45.8 27.9 135.3 10.7 3.1 61.5 1.6 38.4 51.8 84.9 27.6 64.3 34.6 105.4 112.9 59.2 42.4 46.9 17.3 73.8 52.8 19.8 44.6 13.7 80.9 29.7 24.0 67.3 4.6 15.0 27.5 56.7 5.2 14.6 22.0 52.5 26.4 48.4 22.3 59.8 57.4 26.0 44.1 30.8 70.3 30.9 19.6 24.2 33.3 111.7 196.1 20.7 483.4 844.2 694.6 185.7 442.7 90.4 47.0 66.9 109.8 312.2 38.2 72.0 93.5 756.8 73.0 385.2 25.5 90.8 577.4 26.6 28.5 27.1 32.4 24.5 30.5 37.3 28.8 31.3 28.4 31.8 31.1 46.2 22.4 27.4 3.9 12.1 11.6 30.7 112.4 16.5 1.0 54.8 56.0 12.0 32.9 41.6 36.8 6.2 15.7 60.1 6.9 9.8 95.5 20.6 75.3 30.8 36.1 7.2 21.0 0.2 446.7 92.4 45.3 11.2 41.1 88.0 19.1 42.1 7.7 118.3 3.3 0.2 12.3 20.3 143.5 18.9 23.4 37.9 97.8 28.4 1.9 107.4 19.4 122.6 0.5 7.0 96.9 22.5 27.1 8.6 66.5 8.6 55.3 78.5 5.6 13.1 13.0 23.8 3.5 36.1 34.4 13.5 13.1 45.0 50.4 18.2 25.2 AHNAK MGC5395 ENSG00000124942 "AHNAK nucleoprotein" Q09666 11 62433542-62556235 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 561.4;fHDF/TERT166: 554.5;TIME: 582.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 395.4" "HPA019010, HPA019070, HPA026643" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA 10000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA019010: AB_1844657, HPA019070: AB_1844656, HPA026643: AB_10670426" "unprognostic (1.39e-1)" "unprognostic (7.84e-2)" "unprognostic (3.46e-1)" "unprognostic (3.19e-1)" "unprognostic (1.96e-2)" "unprognostic (5.99e-2)" "unprognostic (2.53e-1)" "unprognostic (1.63e-2)" "unprognostic (4.84e-2)" "unprognostic (1.98e-3)" "prognostic unfavorable (2.42e-4)" "unprognostic (4.30e-1)" "unprognostic (4.49e-3)" "unprognostic (5.42e-2)" "unprognostic (1.18e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.47e-6)" 243.1 27.9 62.6 43.4 50.2 44.1 190.3 33.7 45.4 183.3 61.0 276.2 49.0 183.3 51.7 248.2 145.5 74.8 115.1 65.0 98.0 59.7 60.1 144.1 36.7 76.2 48.3 125.8 30.3 26.3 16.9 97.3 62.9 88.5 96.6 10.1 127.5 105.7 188.5 334.7 136.6 113.1 60.8 59.5 133.5 18.0 49.0 27.9 64.9 172.2 63.7 142.0 213.3 78.4 188.2 107.9 9.8 44.1 421.8 561.4 70.3 166.0 201.4 103.0 57.4 93.7 64.9 0.2 61.7 554.5 79.8 244.1 41.2 203.7 130.7 154.2 7.3 22.6 173.4 27.9 80.8 31.5 142.2 204.2 233.0 202.4 183.6 131.5 215.4 2.7 21.8 138.8 211.7 72.1 0.4 60.7 3.0 59.6 171.7 0.4 45.1 113.9 227.1 120.2 0.3 9.2 167.5 69.3 69.0 198.8 133.7 28.4 582.1 182.4 119.8 229.8 74.4 25.0 5.4 0.6 138.2 10.1 60.9 44.1 75.6 0.3 38.7 45.0 25.8 20.0 24.8 31.7 73.8 16.1 3.2 17.3 1.1 31.5 37.8 20.2 21.5 36.8 62.6 50.2 33.7 45.4 65.0 98.0 76.2 48.3 62.9 60.8 49.0 78.4 413.1 439.1 106.3 49.3 171.4 479.4 133.8 285.0 253.2 1.4 173.0 226.8 199.9 195.9 224.1 193.1 0.0 110.8 194.3 400.8 13.7 99.6 10.6 188.5 195.0 282.5 47.6 43.7 0.9 64.1 145.6 312.9 538.2 351.2 238.9 4.3 201.4 88.5 79.4 1.7 0.8 164.8 138.4 329.8 458.3 33.2 451.4 292.3 318.4 43.1 284.8 30.7 138.0 0.5 0.4 262.5 195.5 466.0 329.0 202.4 262.3 6.8 149.3 1.2 177.5 349.5 244.4 3.1 8.1 596.4 610.3 102.2 256.5 3.0 101.8 198.0 AHR bHLHe76 ENSG00000106546 "Aryl hydrocarbon receptor" P35869 7 16916359-17346152 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Cancer-related genes, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 262.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTCEpi: 71.0;hTERT-HME1: 73.8;OE19: 61.2;RT4: 63.2" "CAB005072, HPA029722, HPA029723" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Cytosol Nucleoplasm "CAB005072: AB_633731, HPA029722: AB_10599189, HPA029723: AB_10599025" "unprognostic (1.29e-2)" "unprognostic (1.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-2)" "unprognostic (7.28e-2)" "unprognostic (1.22e-1)" "unprognostic (1.44e-1)" "unprognostic (3.39e-1)" "unprognostic (4.32e-2)" "unprognostic (9.98e-2)" "unprognostic (1.24e-3)" "unprognostic (2.89e-1)" "unprognostic (7.53e-3)" "unprognostic (2.00e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-2)" "unprognostic (9.45e-2)" 22.3 15.0 1.4 25.8 2.7 44.1 19.5 1.4 2.8 14.5 2.3 13.7 16.4 8.8 7.0 17.4 10.5 33.7 9.5 1.9 1.3 7.1 45.0 37.6 15.4 5.4 1.9 6.9 5.8 6.6 3.0 17.7 3.9 11.0 16.3 4.0 10.5 11.2 2.2 22.0 14.5 15.2 2.8 18.7 25.2 2.9 2.7 9.7 12.7 6.5 19.8 49.5 15.0 5.8 8.2 6.6 2.6 0.0 19.2 13.1 1.2 16.5 23.9 7.5 10.8 8.2 17.5 0.0 5.0 24.4 29.7 21.8 1.6 15.1 19.7 0.4 3.6 4.8 8.1 7.3 35.5 8.1 11.5 18.1 71.0 28.8 73.8 33.8 25.3 0.0 0.7 0.2 34.3 4.2 0.0 12.6 2.1 61.2 10.3 0.0 0.0 0.3 23.5 63.2 2.4 0.0 12.4 13.0 12.5 19.0 9.4 2.7 4.3 3.1 0.1 40.7 0.0 3.3 0.1 0.0 51.6 30.6 51.9 0.8 5.6 4.2 0.5 2.6 0.7 0.6 1.7 1.0 6.9 0.7 0.9 0.7 0.6 2.1 1.0 1.6 2.1 1.7 1.4 2.7 1.4 2.8 1.9 1.3 5.4 1.9 3.9 2.8 2.7 5.8 78.3 150.6 76.2 1.6 15.2 75.3 47.6 67.9 104.2 37.0 23.4 30.0 14.7 34.3 84.9 7.3 8.4 3.3 13.6 23.9 0.0 19.3 6.2 39.1 8.4 78.1 5.4 8.6 18.0 15.7 1.8 57.0 56.1 78.8 133.1 0.6 52.1 48.3 24.4 43.7 39.2 12.9 30.5 88.4 262.6 3.2 3.7 107.1 71.2 8.4 70.1 0.9 5.2 1.5 40.6 33.3 19.8 2.6 16.7 48.6 9.9 6.8 51.3 6.1 6.6 14.8 37.8 2.8 2.2 38.3 89.2 21.5 54.7 3.3 19.3 116.1 AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 183.5;liver: 104.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 242.6;Proximal tubular cells: 595.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.1;myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 208.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Enhanced Supported Mitochondria "Intracellular and membrane" NA Yes 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavorable (4.36e-4)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" 24.7 1.9 19.5 6.6 21.0 4.9 26.6 17.8 20.8 6.1 17.5 19.7 4.3 7.0 4.2 23.4 7.6 13.7 51.7 21.4 21.2 183.5 104.0 2.8 1.6 19.0 22.8 4.6 1.2 18.3 4.7 8.3 22.8 16.2 14.0 21.9 9.6 12.7 1.7 27.4 6.6 21.4 18.5 1.2 15.0 11.3 22.7 5.7 2.5 38.8 3.3 19.1 11.8 21.1 73.2 5.0 5.6 23.9 51.6 48.7 12.0 12.1 15.0 25.6 70.8 108.1 8.6 39.1 31.0 19.0 32.1 46.1 18.8 89.9 101.9 33.0 21.5 37.9 21.9 208.6 2.5 29.9 4.6 27.2 49.6 25.1 73.0 42.2 0.9 12.2 48.0 0.6 39.6 31.2 1.1 1.3 24.6 1.0 42.5 0.2 41.0 7.1 37.8 3.2 20.5 15.4 21.6 1.5 16.7 25.8 29.7 12.9 4.2 42.4 36.2 3.3 20.9 39.5 18.8 2.1 68.7 10.9 2.5 0.9 3.1 0.0 0.1 0.6 0.2 0.2 0.1 0.2 2.7 0.1 0.1 0.1 0.4 0.3 0.1 0.4 0.0 0.8 19.5 21.0 17.8 20.8 21.4 21.2 19.0 22.8 22.8 18.5 22.7 21.1 11.2 0.0 0.5 51.2 4.7 49.7 23.6 44.2 63.7 24.5 48.9 44.7 105.7 52.9 14.3 31.3 2.1 2.2 0.6 15.8 56.7 18.6 3.4 30.1 8.2 19.6 5.4 13.9 17.1 12.1 21.1 11.4 27.5 52.2 0.0 36.4 11.7 242.6 3.3 16.8 7.7 8.7 24.4 7.8 9.2 5.8 4.1 6.9 24.9 3.7 5.7 32.7 0.0 9.5 2.5 31.9 4.3 9.4 0.4 38.7 18.8 595.5 12.3 6.5 6.6 5.6 18.8 1.8 9.5 43.1 74.3 4.9 3.6 0.7 23.1 20.4 AKR1A1 "ALR, DD3" ENSG00000117448 "Aldo-keto reductase family 1 member A1" P14550 1 45550543-45570049 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 872.9;Proximal tubular cells: 1215.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006246, HPA017919, HPA019649, HPA027734" Approved Supported Nucleoplasm,Cytosol NA NA 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "CAB006246: AB_425840, HPA017919: AB_1844695, HPA019649: AB_1844696, HPA027734: AB_10600976" "unprognostic (1.73e-1)" "prognostic favorable (2.66e-6)" "unprognostic (4.03e-1)" "prognostic favorable (2.92e-4)" "unprognostic (1.17e-1)" "unprognostic (1.77e-2)" "unprognostic (6.54e-3)" "unprognostic (1.31e-3)" "unprognostic (2.52e-1)" "unprognostic (1.24e-1)" "unprognostic (1.83e-1)" "unprognostic (8.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.56e-2)" "unprognostic (2.46e-1)" "unprognostic (2.89e-2)" "unprognostic (4.57e-2)" 68.8 72.7 37.6 73.4 41.4 48.6 123.1 41.3 38.9 84.0 49.1 106.6 188.7 59.9 90.7 151.9 88.9 61.7 67.6 37.2 41.0 323.5 323.7 75.8 97.3 44.0 39.3 61.8 158.1 60.8 99.4 63.9 44.1 75.9 115.4 23.2 123.0 60.0 46.5 73.5 171.6 79.0 43.3 92.5 112.9 21.1 44.4 77.3 80.7 42.6 117.0 72.3 70.9 53.2 74.3 94.5 91.2 73.7 173.1 124.8 67.9 78.3 178.0 68.8 133.5 40.1 50.3 179.5 68.5 86.2 71.6 94.5 94.0 118.3 60.0 74.3 92.6 101.2 82.2 167.8 152.0 132.4 102.7 140.2 104.7 87.0 157.4 123.4 154.7 125.1 59.4 131.2 77.1 49.1 147.3 61.2 106.0 219.4 68.2 170.1 119.5 211.9 185.5 89.3 117.5 65.3 71.8 271.1 108.5 113.2 80.3 72.3 97.2 30.2 72.0 113.1 54.2 97.0 140.5 87.6 59.1 168.7 26.6 141.8 229.5 45.4 65.3 224.5 71.6 99.8 59.6 63.5 196.8 108.9 51.4 52.4 11.1 66.1 174.8 170.0 81.9 182.7 37.6 41.4 41.3 38.9 37.2 41.0 44.0 39.3 44.1 43.3 44.4 53.2 53.0 48.1 57.3 7.2 96.6 49.2 99.3 210.0 87.6 21.2 121.0 94.7 46.1 95.8 173.8 79.1 37.5 115.2 45.1 113.7 181.9 195.9 5.4 48.7 49.1 58.6 118.4 48.0 8.3 156.5 142.1 82.0 135.5 54.7 112.1 59.2 78.1 294.5 399.3 16.8 7.1 201.9 118.0 141.8 153.7 9.6 68.3 142.1 81.8 20.6 140.3 33.6 49.4 9.0 16.2 123.6 199.9 56.1 187.2 115.1 872.9 1215.0 131.6 38.0 6.6 40.3 132.5 5.9 32.2 158.5 47.0 67.9 49.5 59.0 198.5 129.6 AL163636.1 ENSG00000259171 "Novel protein, ANG-RNASE4 readthrough" 14 20684587-20700576 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 115.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 0.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "classical monocyte: 9.9;memory B-cell: 3.6;myeloid DC: 5.8" "Group enriched" "Detected in many" 12 "B-cells: 3.6;dendritic cells: 5.8;monocytes: 9.9" "Cell line enhanced" "Detected in many" "ASC diff: 17.2;ASC TERT1: 38.5;Hep G2: 26.0;HSkMC: 16.9;OE19: 75.0" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "unprognostic (1.88e-1)" "unprognostic (3.10e-2)" "unprognostic (1.34e-1)" "unprognostic (1.08e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-3)" "unprognostic (1.93e-1)" "unprognostic (1.27e-1)" "unprognostic (2.60e-1)" "unprognostic (8.66e-2)" "unprognostic (6.61e-2)" "unprognostic (6.87e-3)" "unprognostic (8.58e-3)" "unprognostic (2.88e-1)" "unprognostic (2.53e-2)" "unprognostic (5.11e-2)" 45.2 5.8 1.0 6.8 0.7 0.1 34.7 0.6 1.6 31.7 1.5 29.5 26.5 25.1 10.6 11.8 27.3 48.0 14.9 0.8 1.5 15.6 115.1 23.7 5.4 1.2 0.9 69.7 19.4 3.3 3.1 2.6 1.1 41.4 35.1 0.3 35.1 16.5 6.7 17.9 31.7 17.9 1.3 3.6 58.4 7.1 0.8 1.5 8.2 14.6 5.1 24.7 25.7 1.6 2.6 0.8 2.0 0.0 17.2 38.5 0.0 2.4 6.4 0.0 1.7 0.0 2.7 0.0 0.0 10.2 2.7 0.8 0.6 0.2 0.0 6.4 0.4 0.4 0.0 26.0 1.3 0.0 0.0 16.9 1.4 0.0 0.9 12.1 0.5 1.8 0.0 11.6 2.9 0.0 0.2 0.5 0.0 75.0 0.3 0.3 1.4 2.1 0.1 0.9 0.0 0.2 4.0 1.6 2.0 0.0 1.9 0.2 1.8 3.3 0.6 2.0 0.4 2.2 1.6 0.0 3.2 0.4 3.8 0.0 9.9 0.0 0.0 0.5 0.3 3.6 0.4 0.2 5.8 1.2 0.2 0.0 0.1 0.0 0.0 1.0 0.5 2.4 1.0 0.7 0.6 1.6 0.8 1.5 1.2 0.9 1.1 1.3 0.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALDH1A1 "ALDH1, PUMB1, RALDH1" ENSG00000165092 "Aldehyde dehydrogenase 1 family member A1" P00352 9 72900671-73080442 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1500.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 389.4;Hepatocytes: 624.4;Leydig cells: 406.4;Proximal tubular cells: 375.4;Respiratory ciliated cells: 583.7" "Cancer enhanced" "Detected in all" "liver cancer: 399.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "classical monocyte: 87.3" "Lineage enriched" "Detected in many" 33 "monocytes: 87.3" "Cell line enhanced" "Detected in many" "A549: 4019.8;Hep G2: 1269.3;RPTEC TERT1: 710.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 378.3" "HPA002123, CAB020690" Enhanced Approved Enhanced Cytosol NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "CAB020690: , HPA002123: AB_1844722" "unprognostic (8.46e-3)" "prognostic favorable (7.77e-5)" "unprognostic (5.59e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-2)" "unprognostic (8.71e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (4.53e-2)" "unprognostic (6.83e-2)" "unprognostic (4.45e-2)" "unprognostic (3.73e-1)" "unprognostic (3.24e-3)" "unprognostic (2.20e-1)" "unprognostic (2.36e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-3)" 109.4 182.4 51.3 28.4 71.9 31.8 64.3 125.1 72.4 121.8 35.7 218.2 549.7 139.3 583.4 41.3 184.3 175.4 53.7 64.6 62.1 335.4 1500.8 142.6 31.2 93.4 370.7 222.7 498.1 24.3 164.4 32.0 84.7 57.2 88.8 0.4 104.5 245.4 66.7 17.2 304.3 117.0 104.2 77.5 568.5 149.5 74.5 19.8 211.7 83.0 21.6 31.6 90.7 106.1 0.0 4019.8 0.4 0.0 22.4 0.2 1.4 139.6 0.0 0.1 0.1 136.2 0.0 0.1 50.5 0.0 0.3 2.6 0.0 0.2 0.1 0.4 0.1 232.1 0.6 1269.3 13.7 0.6 0.3 6.7 0.1 0.0 0.0 0.3 143.0 0.0 16.9 0.0 153.3 7.2 0.2 1.8 0.7 7.2 0.4 0.5 44.0 1.8 710.6 1.1 0.3 1.4 0.3 0.4 2.9 0.2 0.0 0.5 0.7 0.0 3.5 0.5 0.3 0.4 0.2 1.0 0.0 1.7 0.4 0.0 87.3 1.4 0.0 14.9 0.0 0.0 0.2 0.1 1.4 0.7 0.0 0.0 2.6 0.0 1.1 1.0 0.0 30.3 51.3 71.9 125.1 72.4 64.6 62.1 93.4 370.7 84.7 104.2 74.5 106.1 4.9 96.1 107.6 31.3 6.9 2.7 18.3 168.3 1.2 0.4 12.6 1.7 4.3 187.3 361.1 115.8 0.0 1.7 0.1 20.2 389.4 71.6 12.6 6.3 125.2 26.4 54.9 96.1 3.5 349.7 1.0 102.7 258.4 8.1 158.9 0.2 133.5 624.4 134.4 0.0 0.5 168.9 138.4 109.6 5.1 37.8 406.4 61.7 7.2 17.8 46.0 0.0 2.1 0.0 0.7 128.4 77.4 207.3 1.3 2.0 267.4 375.4 583.7 0.3 26.3 334.2 28.6 8.6 4.6 21.5 3.1 2.5 8.8 129.6 131.7 26.5 ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 857.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 857.0;monocytes: 940.8;Proximal tubular cells: 882.0" "Cancer enhanced" "Detected in all" "liver cancer: 71.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.0;myeloid DC: 213.2" "Group enriched" "Detected in many" 4 "dendritic cells: 213.2;monocytes: 212.0" "Cell line enhanced" "Detected in many" "ASC diff: 86.8;HHSteC: 97.0;OE19: 152.2;SK-BR-3: 201.0;THP-1: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 2200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" 303.8 102.4 139.7 39.8 146.1 29.2 77.2 136.5 163.5 25.0 123.3 73.3 73.7 30.1 21.3 73.6 32.3 37.4 111.3 132.2 139.7 177.7 857.7 111.6 18.7 140.7 144.9 42.0 23.3 2.6 23.3 7.0 141.1 34.6 72.3 29.2 32.4 29.5 130.8 127.9 74.8 30.2 143.0 20.6 101.5 13.0 151.8 27.1 30.8 165.7 52.9 50.0 29.0 144.5 8.8 13.1 18.7 31.9 86.8 13.0 60.9 9.3 16.8 4.3 3.1 23.5 12.1 0.5 45.3 20.8 11.9 16.2 0.1 4.6 2.7 0.6 6.1 0.7 8.4 64.7 97.0 0.9 0.9 23.9 22.6 14.8 0.3 17.7 26.9 0.9 17.9 3.0 4.1 0.5 1.0 23.4 24.8 152.2 2.1 0.6 0.4 1.9 31.4 0.6 7.5 23.1 22.8 201.0 0.2 33.7 20.3 92.1 1.1 0.4 16.5 0.6 0.4 5.5 3.0 25.7 22.0 0.8 0.4 6.5 212.0 51.1 0.7 93.0 0.9 6.2 0.3 0.7 213.2 5.2 0.7 0.5 10.7 3.4 25.4 70.6 0.5 123.5 139.7 146.1 136.5 163.5 132.2 139.7 140.7 144.9 141.1 143.0 151.8 144.5 27.7 147.4 242.7 51.2 22.6 60.0 205.2 311.1 80.8 78.7 35.0 23.7 378.9 165.8 243.1 66.2 18.8 62.4 48.6 260.3 399.2 127.5 4.3 27.8 24.5 66.2 55.2 42.1 11.7 218.0 127.5 103.1 200.3 47.7 30.9 29.0 139.6 857.0 129.2 35.3 18.2 231.0 101.7 278.5 124.1 10.6 79.9 189.3 35.6 26.2 940.8 130.2 8.2 14.1 6.8 130.2 366.5 149.0 12.5 84.4 384.3 882.0 89.4 42.6 46.0 46.0 67.6 3.0 3.9 105.1 124.7 42.1 13.1 81.0 272.6 150.4 ALDOA ENSG00000149925 "Aldolase, fructose-bisphosphate A" P04075 16 30064164-30070457 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease variant, Glycogen storage disease, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 26754.8;tongue: 9180.4" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 3267.9;Extravillous trophoblasts: 2322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004177, CAB006252" Supported Approved Cytosol NA NA 640000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB006252: AB_437007, HPA004177: AB_1078128" "unprognostic (2.63e-2)" "unprognostic (3.22e-2)" "unprognostic (6.80e-2)" "unprognostic (1.33e-1)" "unprognostic (6.74e-3)" "unprognostic (4.28e-3)" "prognostic unfavorable (5.79e-5)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.68e-1)" "unprognostic (1.81e-1)" "unprognostic (2.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.19e-3)" "unprognostic (4.48e-2)" 569.3 696.4 616.8 443.1 697.4 732.5 512.6 617.3 719.7 566.0 617.0 774.1 517.9 533.7 201.0 1302.0 449.7 420.5 2286.1 731.9 652.0 709.0 217.1 425.6 358.2 762.3 654.0 510.4 390.5 943.1 525.1 351.4 763.9 457.7 400.1 465.2 904.9 597.6 26754.8 643.4 488.3 465.2 545.5 417.5 595.0 138.7 657.8 280.9 454.5 9180.4 478.3 761.8 740.3 558.7 2206.1 1620.4 477.9 1542.8 714.6 808.5 1520.8 1297.9 1336.2 1291.6 1603.0 1158.1 1643.6 1487.6 2072.2 1318.6 708.6 1632.6 966.8 2829.1 939.3 658.5 1272.9 1219.3 1202.7 2591.1 1112.5 1793.8 1251.3 1115.7 979.6 1455.4 968.9 2119.7 965.4 686.9 1070.0 951.1 1393.4 3136.7 1100.2 1477.0 1192.8 848.1 1346.6 1613.9 765.2 3353.2 1629.4 1230.5 950.7 668.5 808.6 3368.5 1213.9 591.2 1433.0 1194.7 1162.5 1892.3 750.3 1046.7 1430.0 1861.5 1387.3 1369.3 3524.5 1715.9 1532.9 2050.6 2694.7 2081.7 1008.7 2466.5 1138.1 908.5 1091.7 1047.0 2182.7 877.9 1027.4 996.9 2531.7 819.9 2780.2 824.0 1476.3 4372.2 616.8 697.4 617.3 719.7 731.9 652.0 762.3 654.0 763.9 545.5 657.8 558.7 17.0 12.8 32.4 83.2 281.2 792.0 716.4 3267.9 784.8 387.4 34.4 21.6 1968.4 273.1 1385.1 42.3 118.9 1194.1 107.9 1834.8 111.6 120.9 258.8 15.8 11.8 261.1 323.9 215.8 66.2 76.2 2322.1 329.7 513.3 16.1 196.5 18.7 289.5 102.0 1181.9 733.6 70.0 755.1 1265.4 632.2 715.4 1152.4 380.8 388.8 924.9 50.6 417.7 662.1 328.5 40.2 60.8 126.2 1497.1 405.1 409.4 676.9 1755.7 75.8 700.9 298.9 486.4 680.9 572.9 25.8 123.6 1174.6 684.5 1361.3 294.3 15.2 937.7 1146.2 ALOX15B 15-LOX-2 ENSG00000179593 "Arachidonate 15-lipoxygenase type B" O15296 17 8039034-8049134 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 111.7;prostate: 73.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 75.8;Basal respiratory cells: 22.0;Kupffer cells: 42.2;monocytes: 87.9;Prostatic glandular cells: 25.6;Squamous epithelial cells: 44.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 91.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "classical monocyte: 3.9;myeloid DC: 4.3" "Group enriched" "Detected in many" 8 "dendritic cells: 4.3;monocytes: 3.9" "Cell line enhanced" "Detected in some" "HHSteC: 7.7;HSkMC: 16.6;hTCEpi: 35.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010562 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Cytosol" "HPA010562: AB_2668305" "unprognostic (1.76e-2)" "unprognostic (6.47e-2)" "unprognostic (2.56e-1)" "unprognostic (2.28e-3)" "unprognostic (1.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.59e-1)" "unprognostic (1.59e-2)" "unprognostic (9.37e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.49e-2)" 2.2 1.7 0.7 1.3 0.7 0.4 111.7 0.6 2.5 12.0 0.5 2.3 0.1 1.1 0.9 39.1 1.6 0.7 0.7 0.7 0.8 0.5 0.4 24.5 2.9 1.8 0.9 0.7 1.4 0.2 0.5 1.2 1.6 73.1 0.3 0.3 3.7 0.1 0.3 36.9 3.7 0.1 0.9 3.8 4.4 0.5 0.9 0.7 1.9 0.1 7.6 1.7 33.4 1.9 0.1 0.0 0.0 0.1 0.5 0.7 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 16.6 35.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.9 0.7 0.7 0.6 2.5 0.7 0.8 1.8 0.9 1.6 0.9 0.9 1.9 1.4 0.0 75.8 0.0 0.3 3.1 0.6 22.0 7.4 0.0 19.8 12.3 0.3 1.5 8.2 0.0 0.0 0.2 0.2 0.2 0.0 0.1 1.3 0.0 0.8 0.4 0.0 0.0 0.2 0.4 0.0 0.2 0.0 0.2 1.3 0.0 0.7 0.3 4.2 0.0 0.0 0.0 2.0 42.2 1.1 0.8 0.0 15.4 5.4 0.0 87.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 25.6 0.0 0.0 2.2 0.0 0.0 0.1 1.3 0.6 0.8 44.4 1.1 0.8 0.0 0.0 0.0 2.2 AMY2B AMY2 ENSG00000240038 "Amylase alpha 2B" P19961 1 103553815-103579534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 122 "pancreas: 31246.7" "Cell type enhanced" "Detected in many" "Astrocytes: 56.2;Excitatory neurons: 61.2;Exocrine glandular cells: 148.0;Inhibitory neurons: 48.4;Oligodendrocytes: 41.8" "Cancer enriched" "Detected in many" 15 "pancreatic cancer: 25.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 5.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.8;EFO-21: 10.3" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 77000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (8.69e-4)" "unprognostic (3.71e-3)" "unprognostic (6.41e-2)" "unprognostic (9.75e-2)" "unprognostic (1.32e-1)" "unprognostic (1.51e-4)" "unprognostic (1.21e-2)" "unprognostic (1.63e-2)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-2)" "unprognostic (7.41e-3)" "unprognostic (1.55e-2)" "unprognostic (5.74e-2)" "unprognostic (4.22e-1)" "unprognostic (3.12e-4)" 35.4 24.8 29.5 11.2 34.8 13.4 34.9 39.9 38.6 40.8 19.7 33.0 16.5 22.7 20.2 13.1 50.3 14.1 40.9 27.9 29.5 59.4 39.0 30.2 20.0 27.7 29.1 40.0 31246.7 14.9 36.8 6.9 27.1 35.3 11.9 69.8 256.2 14.6 63.7 42.6 31.7 9.8 26.3 34.8 18.1 5.2 30.6 12.6 63.5 25.2 13.8 29.3 25.8 30.0 0.0 0.5 1.1 0.0 5.6 9.8 1.1 0.8 0.8 0.6 1.5 0.0 0.2 1.0 10.3 0.3 0.0 1.2 0.1 1.3 1.4 1.3 1.6 1.9 4.5 0.8 0.8 2.5 2.6 6.7 6.7 0.8 1.2 1.8 0.2 3.0 0.0 3.2 0.9 0.0 1.9 0.5 0.1 0.1 1.4 0.5 0.0 4.7 5.7 2.0 2.8 0.6 2.4 1.1 0.8 1.8 0.1 1.4 0.8 0.3 0.9 0.5 0.7 3.5 0.1 0.3 1.9 1.8 0.2 0.0 5.0 1.0 0.4 2.5 0.3 1.0 0.1 0.2 1.6 0.9 0.6 0.2 1.2 0.1 2.2 0.5 0.2 1.2 29.5 34.8 39.9 38.6 27.9 29.5 27.7 29.1 27.1 26.3 30.6 30.0 2.8 12.8 20.1 56.2 3.2 4.7 4.2 1.4 0.6 11.7 2.9 2.7 7.2 2.8 11.2 1.8 33.3 0.4 2.4 3.6 0.0 1.3 7.3 1.1 0.6 2.7 4.9 1.3 61.2 148.0 0.4 3.2 2.0 0.7 3.8 0.5 2.2 6.5 1.6 10.1 48.4 2.5 0.0 9.4 3.5 2.7 2.5 3.4 5.4 11.2 4.0 3.1 2.1 22.1 41.8 1.3 2.7 1.9 1.4 1.5 4.3 0.8 14.6 15.4 0.0 1.0 2.5 1.5 0.9 0.4 3.0 0.3 1.7 0.4 2.2 1.6 ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 3018.1" "Cell type enriched" "Detected in many" 24 "Hepatocytes: 4816.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.5;myeloid DC: 14.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Hep G2: 152.2;OE19: 116.1" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" Yes No 308000000 410000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" 37.6 3.0 3.6 6.0 3.5 1.0 37.8 3.5 4.9 38.2 5.6 32.6 23.2 23.4 17.9 9.8 30.5 28.5 16.9 3.6 4.9 18.4 3018.1 18.5 3.5 4.5 4.2 58.1 30.8 5.3 5.0 3.8 4.3 32.7 45.7 2.2 52.6 13.3 6.2 27.4 27.1 10.4 4.5 7.4 58.2 10.2 3.7 1.5 8.8 10.5 4.1 24.8 31.4 4.8 3.7 9.9 2.3 0.0 23.9 27.8 0.3 4.8 8.8 1.1 4.0 5.9 5.1 0.4 1.5 12.0 8.0 3.8 2.8 3.1 1.3 18.4 3.8 0.9 5.1 152.2 5.0 4.0 0.5 22.2 2.5 1.5 5.1 11.8 5.7 4.2 0.2 27.0 3.5 0.7 0.9 1.2 0.7 116.1 10.7 0.7 3.9 11.3 2.3 2.9 0.0 0.4 4.6 1.7 6.5 5.1 4.0 0.7 6.0 1.9 2.8 1.7 0.7 5.9 4.8 0.5 3.2 2.0 5.0 0.0 24.5 0.0 0.6 2.9 0.4 5.8 1.2 1.1 14.5 4.9 0.3 0.2 0.4 0.0 0.1 2.3 0.8 7.1 3.6 3.5 3.5 4.9 3.6 4.9 4.5 4.2 4.3 4.5 3.7 4.8 9.7 28.9 17.7 0.0 9.7 27.1 43.3 39.2 14.2 0.1 33.8 24.8 0.8 194.5 24.6 11.0 0.0 1.6 0.7 32.5 11.7 40.0 1.0 6.2 9.7 11.0 71.0 27.8 0.0 31.6 5.3 48.8 56.1 24.9 0.0 10.7 62.4 4816.3 15.9 0.0 0.0 171.9 12.2 95.9 18.7 2.9 71.1 13.8 23.2 0.0 4.9 10.1 0.0 0.0 0.0 21.6 33.3 24.0 11.7 43.7 91.3 61.2 76.5 0.6 13.1 29.7 17.7 1.0 1.3 9.4 52.4 9.3 5.6 0.5 51.6 39.2 ANKRD35 FLJ25124 ENSG00000198483 "Ankyrin repeat domain 35" Q8N283 1 145866560-145885866 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 60.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 56.4;Fibroblasts: 31.2;Leydig cells: 36.4;Muller glia cells: 57.7;Peritubular cells: 50.8;Skeletal myocytes: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.6;THP-1: 6.8;TIME: 8.4;U-87 MG: 8.3;U-937: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035453 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA035453: AB_10672864" "prognostic favorable (9.35e-4)" "prognostic favorable (2.90e-4)" "unprognostic (2.07e-1)" "unprognostic (7.39e-3)" "unprognostic (1.77e-2)" "unprognostic (1.02e-2)" "unprognostic (3.27e-1)" "unprognostic (3.58e-2)" "unprognostic (3.03e-1)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (5.86e-2)" "unprognostic (9.29e-10)" "unprognostic (8.80e-3)" "unprognostic (2.18e-1)" "unprognostic (5.92e-2)" "unprognostic (8.69e-3)" 4.0 1.3 8.2 1.1 7.9 0.3 4.6 7.6 9.7 20.6 6.4 6.0 0.5 5.8 1.4 24.7 6.6 1.3 2.9 7.5 8.6 0.8 2.5 2.3 0.4 8.7 9.5 4.4 0.7 0.0 2.0 0.1 8.5 6.6 0.8 1.3 11.4 2.7 8.2 60.8 2.5 2.1 8.4 0.5 3.9 1.6 9.0 0.5 1.7 3.8 6.7 7.3 20.6 7.6 0.1 0.0 0.0 0.0 2.2 9.6 0.2 1.4 3.6 0.4 1.2 0.4 0.0 0.0 0.3 1.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 1.1 2.9 0.1 3.3 0.4 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.2 0.0 0.0 3.9 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 8.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.3 7.5 0.0 0.0 2.1 0.0 0.7 0.8 0.1 0.0 0.3 1.1 0.3 0.0 0.2 0.7 0.1 0.7 0.2 0.5 0.7 0.7 8.2 7.9 7.6 9.7 7.5 8.6 8.7 9.5 8.5 8.4 9.0 7.6 1.6 0.0 0.0 6.8 0.3 4.6 16.8 10.2 0.0 1.1 6.3 13.5 1.5 2.8 9.5 1.8 0.0 0.1 2.2 0.0 0.0 0.0 3.5 56.4 10.9 1.3 0.0 2.7 5.6 0.4 0.1 31.2 0.5 17.2 19.1 0.0 2.2 13.9 11.0 0.0 2.1 0.0 14.2 1.2 4.6 5.9 36.4 1.1 5.4 1.0 1.1 57.7 5.2 3.0 0.6 0.1 0.0 50.8 0.4 5.3 0.0 0.1 9.8 2.7 0.0 29.5 6.4 0.1 1.0 10.4 12.4 0.3 5.5 1.1 0.0 13.6 ANO10 "FLJ10375, MGC47890, SCAR10, TMEM16K" ENSG00000160746 "Anoctamin 10" Q9NW15 3 43354859-43691594 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 123.3;Excitatory neurons: 77.4;Inhibitory neurons: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016624, HPA051569" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA016624: , HPA051569: AB_2681537" "unprognostic (1.51e-3)" "unprognostic (1.38e-2)" "prognostic favorable (6.70e-4)" "prognostic favorable (1.11e-4)" "unprognostic (4.23e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (7.99e-3)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.41e-6)" "unprognostic (9.83e-3)" "unprognostic (1.22e-1)" "unprognostic (5.19e-3)" "unprognostic (5.71e-2)" 26.6 14.1 17.6 15.1 18.6 33.0 21.8 23.9 20.9 22.3 18.4 39.4 61.1 21.6 13.6 25.3 13.9 19.4 12.7 18.1 21.1 29.9 14.1 16.9 7.6 22.7 22.9 13.9 15.2 23.7 13.9 18.1 23.2 14.2 33.7 10.1 28.6 20.2 15.5 32.0 54.7 28.0 19.6 9.1 13.5 13.0 19.8 7.1 24.5 11.6 9.7 18.1 21.5 24.1 30.6 23.6 26.1 27.4 101.1 53.5 31.2 87.7 141.1 42.0 54.4 16.2 27.5 3.1 27.4 114.8 43.1 16.3 20.6 47.0 52.6 33.6 14.2 39.4 28.7 17.7 43.9 7.2 31.1 50.5 36.3 53.6 71.8 79.4 100.3 18.7 30.8 24.9 95.2 20.8 7.8 5.2 31.3 23.7 28.6 6.3 18.7 10.2 85.5 31.4 6.4 19.4 34.4 27.0 19.8 45.3 59.5 14.5 84.7 66.2 24.4 70.2 40.7 15.7 22.9 1.1 60.2 14.6 44.2 7.4 19.0 1.4 6.7 11.1 3.8 2.7 4.6 4.5 13.1 2.5 3.9 6.0 32.8 9.7 12.7 2.3 5.4 7.0 17.6 18.6 23.9 20.9 18.1 21.1 22.7 22.9 23.2 19.6 19.8 24.1 24.3 6.4 3.2 70.2 4.1 5.6 5.8 6.9 8.0 8.0 18.2 8.4 5.2 8.6 13.2 14.7 0.0 14.4 3.7 38.5 123.3 21.6 2.9 11.8 23.6 17.8 9.6 11.8 77.4 17.8 19.5 10.6 10.2 31.2 2.5 6.8 23.6 10.7 11.6 10.1 97.9 23.8 10.2 9.6 5.3 5.2 5.6 9.1 14.2 69.3 9.2 17.1 5.2 71.4 46.4 11.7 22.1 10.1 2.6 4.4 58.4 19.0 4.0 3.6 6.6 19.1 15.7 17.1 23.6 8.7 6.1 17.1 5.8 6.2 26.9 4.8 ANXA2 "ANX2, ANX2L4, CAL1H, LIP2, LPC2D" ENSG00000182718 "Annexin A2" P07355 15 60347134-60402883 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2185.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5755.6;Pancreatic endocrine cells: 5217.8;Prostatic glandular cells: 4575.5;Urothelial cells: 4326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 4429.7;classical monocyte: 2762.3;intermediate monocyte: 2401.9;myeloid DC: 4018.8;non-classical monocyte: 2686.5;T-reg: 1681.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 174.7" "CAB004311, HPA046964, HPA061798" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 19000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" Cytosol "CAB004311: AB_626677, HPA046964: AB_2732537, HPA061798: AB_2732671" "unprognostic (1.61e-1)" "unprognostic (1.31e-3)" "unprognostic (1.84e-1)" "prognostic favorable (6.88e-5)" "unprognostic (4.06e-3)" "unprognostic (5.42e-3)" "prognostic unfavorable (2.54e-5)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.94e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (7.74e-2)" "unprognostic (2.55e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.59e-5)" 975.6 370.5 49.0 461.9 50.5 151.7 708.5 49.6 96.9 806.3 95.6 631.2 502.0 296.2 267.2 2185.3 388.4 453.9 393.0 47.6 79.4 358.3 185.5 878.3 200.7 90.0 83.6 187.0 324.3 344.0 163.9 650.4 84.9 399.3 606.1 30.2 933.4 386.4 304.8 1140.8 487.5 425.4 73.3 301.6 379.0 116.1 120.9 188.7 351.2 205.8 541.1 842.2 1256.7 80.1 4183.3 4421.4 223.6 105.5 2962.4 4744.2 971.0 4703.6 2968.4 2868.4 2534.9 2083.5 1903.6 10.0 3907.2 5983.6 2185.1 4304.9 992.9 8695.5 3113.5 846.8 103.9 78.2 1918.7 882.7 1782.0 4.5 59.9 2324.4 2278.6 2013.2 4335.0 3477.2 5455.0 58.4 320.9 447.9 6271.8 468.4 18.5 239.1 508.2 3444.1 3283.5 48.9 1198.8 226.6 5172.4 2410.7 295.1 171.9 1774.5 424.8 1942.8 2305.1 922.7 173.6 6336.8 2534.1 3406.8 8668.0 4807.4 172.6 616.3 83.8 2449.2 47.9 5206.0 4429.7 2762.3 355.0 603.8 2401.9 668.5 657.9 686.4 701.7 4018.8 412.1 77.0 313.9 73.6 287.1 2686.5 609.4 1681.4 3754.4 49.0 50.5 49.6 96.9 47.6 79.4 90.0 83.6 84.9 73.3 120.9 80.1 673.9 2141.0 414.8 0.3 101.3 2512.2 3396.9 5755.6 246.4 2.5 395.9 337.4 28.2 773.5 3086.6 560.9 0.0 1874.5 135.9 933.6 13.7 3941.4 93.0 855.9 457.1 772.0 103.4 38.7 0.2 2411.4 2714.4 1076.7 328.7 1376.3 105.7 97.5 474.0 64.2 1537.2 0.0 1.3 689.0 1668.2 429.6 1992.1 126.6 771.1 715.1 1417.6 15.9 1284.0 19.4 138.0 1.5 0.1 5217.8 920.9 638.7 144.5 4575.5 845.8 51.8 2446.8 8.1 184.1 437.7 831.1 13.0 29.3 789.7 2325.1 1150.1 224.1 8.6 749.9 4326.1 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512941-36724549 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.3;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 77.9;Kupffer cells: 119.7;Macrophages: 77.1;Microglial cells: 233.3;monocytes: 67.5;NK-cells: 90.6;T-cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 298.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "GAMG: 4.8;NB-4: 26.5;THP-1: 20.2;U-937: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA021666, HPA026716" Approved Uncertain Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 7.5 5.1 2.4 33.7 2.2 43.3 3.8 2.1 3.1 5.7 4.7 10.4 9.5 2.8 1.5 3.3 3.5 15.6 2.0 2.1 3.6 1.9 13.2 12.7 35.1 6.6 5.1 2.6 1.5 1.5 0.9 11.2 5.7 2.5 13.3 0.8 3.7 2.8 0.5 0.8 12.1 9.3 4.0 64.9 7.0 1.3 5.1 13.9 1.8 0.9 15.1 13.9 1.3 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 26.5 0.1 0.0 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 8.9 0.0 1.8 298.5 97.8 43.6 251.9 9.0 2.6 2.2 30.7 183.1 0.3 4.8 37.3 97.9 106.8 113.2 2.7 0.7 207.3 2.4 2.2 2.1 3.1 2.1 3.6 6.6 5.1 5.7 4.0 5.1 8.6 1.3 0.0 9.6 1.3 3.6 0.8 0.1 0.0 0.0 1.1 0.6 1.7 0.5 1.5 2.5 0.0 0.0 0.2 77.9 9.2 1.9 0.3 0.6 0.4 0.3 1.4 15.5 16.0 12.4 0.0 0.2 3.1 2.6 0.4 5.1 0.7 2.5 0.9 32.8 0.0 8.1 0.3 0.0 119.7 20.3 1.2 0.0 77.1 0.0 233.3 67.5 2.8 90.6 12.1 38.6 0.0 3.8 0.4 13.6 0.1 0.3 0.5 0.7 0.3 0.0 0.3 0.5 0.0 0.1 0.4 0.3 0.1 54.1 0.6 0.9 0.2 AP1S2 "MRX59, MRXS5, PGS, SIGMA1B" ENSG00000182287 "Adaptor related protein complex 1 subunit sigma 2" P56377 X 15825806-15854931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "epididymis: 663.3" "Cell type enhanced" "Detected in all" "Hofbauer cells: 259.8;Kupffer cells: 392.6;Langerhans cells: 609.2;Macrophages: 362.7;monocytes: 630.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 13.1;glioma: 22.0;melanoma: 49.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 326.8;intermediate monocyte: 325.0;myeloid DC: 221.1;non-classical monocyte: 175.4;plasmacytoid DC: 82.2" "Group enriched" "Detected in all" 5 "dendritic cells: 221.1;monocytes: 326.8" "Cell line enhanced" "Detected in all" "Karpas-707: 298.0;SK-MEL-30: 442.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049894, HPA060945" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Vesicles" "HPA049894: AB_2680939, HPA060945: AB_2684393" "prognostic favorable (9.86e-4)" "unprognostic (4.62e-2)" "unprognostic (2.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (3.85e-1)" "unprognostic (2.03e-3)" "unprognostic (5.76e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.53e-6)" "unprognostic (1.85e-2)" "unprognostic (5.61e-2)" "unprognostic (5.08e-2)" "unprognostic (6.35e-2)" "unprognostic (3.13e-1)" "unprognostic (9.34e-2)" "unprognostic (6.47e-2)" 28.3 21.4 24.6 36.7 28.4 38.3 15.0 32.0 36.9 31.6 27.3 42.1 11.9 52.2 663.3 21.4 13.5 20.1 74.8 25.1 48.0 13.1 15.9 25.8 33.2 42.7 35.8 8.8 7.8 16.7 19.4 42.0 47.0 11.6 22.0 43.7 9.5 30.5 70.1 14.0 20.1 76.3 34.4 43.0 19.5 23.4 29.6 28.7 12.5 93.7 28.8 26.1 12.7 33.8 12.0 14.2 130.1 78.4 29.5 19.1 5.0 47.1 22.7 31.1 41.1 9.6 11.1 22.6 183.0 72.6 50.4 16.1 31.7 10.8 57.0 30.1 64.9 15.3 16.7 14.7 24.2 63.1 16.9 12.2 11.2 36.0 33.1 50.4 78.1 19.1 14.3 298.0 72.4 8.7 12.9 39.5 171.0 6.4 42.5 29.5 116.7 50.6 37.4 2.5 14.8 69.2 18.4 4.8 442.2 84.1 52.7 69.2 43.9 67.8 21.2 92.5 41.9 25.5 58.7 37.3 33.6 28.0 159.7 50.9 326.8 34.6 21.1 325.0 24.8 30.8 25.5 20.6 221.1 28.0 18.5 18.1 52.8 27.9 175.4 82.2 38.1 228.0 24.6 28.4 32.0 36.9 25.1 48.0 42.7 35.8 47.0 34.4 29.6 33.8 130.8 3.2 13.1 37.2 77.0 55.2 12.7 9.1 8.6 34.7 12.0 11.4 195.6 12.8 3.2 9.2 12.5 5.3 114.2 9.2 33.2 13.7 5.1 50.4 32.6 166.3 26.9 32.6 15.1 6.4 18.9 38.0 7.7 78.0 78.6 15.6 147.4 8.6 259.8 11.8 73.2 8.4 12.2 392.6 609.2 17.5 17.4 362.7 149.4 31.9 630.0 21.1 62.8 19.1 85.0 10.3 14.0 7.2 26.0 19.0 6.5 9.0 1.6 39.3 39.5 26.7 39.1 55.7 28.8 10.6 51.6 5.6 58.3 4.0 8.5 6.7 APLP2 "APPH, APPL2" ENSG00000084234 "Amyloid beta precursor like protein 2" Q06481 11 130068147-130144811 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 249.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039319 Approved Approved Vesicles NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA039319: AB_10673141" "unprognostic (2.83e-2)" "unprognostic (1.29e-1)" "unprognostic (2.06e-1)" "unprognostic (3.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.86e-2)" "unprognostic (2.33e-1)" "unprognostic (2.70e-2)" "unprognostic (3.12e-3)" "unprognostic (7.44e-2)" "prognostic favorable (1.33e-9)" "unprognostic (3.20e-3)" "unprognostic (4.95e-2)" "prognostic favorable (2.90e-4)" "unprognostic (4.42e-2)" 217.2 130.2 125.6 144.0 126.0 196.5 192.3 164.7 157.9 170.4 252.6 209.9 272.4 176.6 138.6 134.2 167.6 201.8 271.6 131.0 153.2 359.9 334.8 391.4 77.5 130.9 137.5 180.8 136.0 291.5 87.1 324.8 133.1 287.7 176.7 540.8 135.3 291.0 65.9 113.3 226.6 211.5 135.4 95.7 149.7 54.9 157.9 81.5 607.8 85.2 56.8 199.1 129.6 152.8 216.7 170.3 307.1 281.2 1259.7 847.8 393.7 598.6 741.1 294.2 251.8 1300.5 1541.3 107.9 1515.3 1422.2 322.4 540.4 229.1 567.6 168.0 165.6 206.4 180.9 116.7 502.9 191.9 556.7 363.8 566.4 367.8 244.5 469.5 1520.2 912.7 34.1 180.7 228.9 495.2 205.7 26.9 245.3 182.8 256.8 301.1 70.0 69.8 105.5 758.9 589.6 109.9 239.0 706.9 368.0 92.0 535.8 582.2 489.5 1567.6 314.1 211.7 496.8 281.9 33.8 50.6 245.5 347.0 487.7 221.0 55.1 249.3 65.3 17.9 122.2 13.5 16.3 12.7 17.0 110.1 44.8 9.4 12.6 160.8 15.6 94.6 10.5 20.0 149.5 125.6 126.0 164.7 157.9 131.0 153.2 130.9 137.5 133.1 135.4 157.9 152.8 239.6 942.3 550.3 37.9 74.4 106.7 175.4 497.0 78.6 967.9 252.9 183.1 262.0 254.5 460.6 404.6 706.8 798.1 72.0 354.2 52.8 305.5 13.6 211.0 191.3 220.3 92.8 156.3 99.0 107.1 130.3 253.5 86.6 432.8 103.5 109.6 127.1 498.2 652.4 240.6 133.5 159.8 463.9 287.6 214.3 13.8 167.4 405.5 96.0 54.4 293.1 396.1 56.7 45.8 31.6 276.5 220.7 214.4 45.5 190.1 352.0 244.9 258.3 729.0 190.7 148.9 207.7 182.8 240.4 81.6 109.4 927.3 58.8 165.9 161.5 215.4 APOL4 APOLIV ENSG00000100336 "Apolipoprotein L4" Q9BPW4 22 36189124-36204840 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 32.7;Enteroendocrine cells: 14.9;Glandular and luminal cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6;myeloid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;monocytes: 1.6" "Cell line enhanced" "Detected in some" "BEWO: 18.7;HDLM-2: 109.9;HSkMC: 16.1;K-562: 23.7;SCLC-21H: 47.9" "HPA049797, HPA055435" Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Vesicles "HPA049797: AB_2680887, HPA055435: AB_2682816" "unprognostic (2.73e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.51e-1)" "unprognostic (5.31e-1)" "unprognostic (3.39e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "prognostic favorable (3.45e-4)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (2.00e-5)" "unprognostic (4.26e-2)" "unprognostic (3.69e-1)" "unprognostic (4.18e-2)" "prognostic favorable (2.40e-6)" 13.5 1.0 0.8 6.0 0.8 1.5 14.7 0.9 2.2 4.6 0.5 3.3 4.8 3.9 1.6 4.3 5.9 6.3 5.3 0.9 1.6 8.1 2.0 12.8 4.7 2.5 1.3 3.9 1.0 0.3 9.4 3.3 1.9 14.7 3.4 0.1 5.8 3.4 1.1 4.1 3.8 2.4 1.0 3.2 4.9 0.7 1.1 2.9 3.2 1.3 1.8 12.1 3.6 0.8 0.0 0.0 0.0 0.0 0.2 2.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 109.9 0.0 5.7 0.0 0.0 0.1 0.0 0.2 16.1 0.0 0.0 0.0 0.0 0.8 0.0 23.7 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 1.0 47.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.3 0.1 0.2 1.6 0.0 0.0 0.9 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.8 0.8 0.9 2.2 0.9 1.6 2.5 1.3 1.9 1.0 1.1 0.8 7.0 0.0 6.7 0.3 0.2 1.3 0.7 1.5 0.0 0.3 4.6 2.2 1.1 1.5 3.4 0.0 0.0 0.5 0.1 0.0 3.9 0.2 0.0 32.7 12.4 6.6 14.9 4.2 0.0 0.7 1.0 10.4 0.0 52.6 2.5 0.0 2.5 0.4 2.3 1.7 0.1 0.8 0.0 6.2 6.5 0.0 2.8 8.8 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 1.2 0.2 0.3 4.2 0.0 0.0 9.0 1.9 0.0 0.0 0.0 1.1 6.2 1.3 0.5 0.4 1.9 ARHGAP22 RhoGAP2 ENSG00000128805 "Rho GTPase activating protein 22" Q7Z5H3 10 48446036-48656265 "Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell type enhanced" "Detected in many" "Late spermatids: 122.7;Microglial cells: 227.7;Oligodendrocyte precursor cells: 141.8;Oligodendrocytes: 200.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 68.8;LHCN-M2: 64.8;TIME: 66.2;U-87 MG: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020696, HPA040391, HPA064439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB020696: , HPA040391: AB_2676957, HPA064439: AB_2685266" "unprognostic (1.87e-1)" "unprognostic (3.98e-2)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.07e-1)" "unprognostic (6.74e-3)" "unprognostic (4.81e-3)" "unprognostic (2.78e-1)" "unprognostic (1.66e-1)" "unprognostic (3.03e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.16e-8)" "unprognostic (7.40e-2)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (3.66e-2)" 2.6 1.9 12.0 3.0 15.7 1.4 1.6 17.6 14.5 1.6 7.7 2.0 0.6 1.1 0.7 1.4 1.8 1.8 4.4 11.9 12.7 1.3 0.8 2.0 2.7 22.6 17.0 4.8 1.7 0.9 2.0 0.8 20.1 3.3 1.0 0.4 2.0 1.1 1.9 2.2 1.6 1.4 16.9 2.8 1.2 4.8 17.0 2.8 6.6 1.6 2.2 2.1 2.2 22.2 6.2 1.4 0.4 0.0 5.1 20.8 4.3 31.9 15.1 3.0 4.1 7.0 0.9 0.0 1.2 13.1 2.1 12.4 0.4 11.2 5.4 0.6 11.5 18.2 0.2 0.1 2.7 2.0 2.0 5.0 11.2 37.1 3.0 68.8 20.6 0.0 17.4 3.0 64.8 0.2 0.2 0.1 7.2 0.0 0.5 0.1 0.0 7.9 6.5 0.7 1.1 6.4 1.5 0.1 0.6 0.6 0.4 0.3 66.2 30.1 0.4 3.8 23.8 0.0 0.0 0.0 82.5 0.3 4.9 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 12.0 15.7 17.6 14.5 11.9 12.7 22.6 17.0 20.1 16.9 17.0 22.2 0.9 0.0 1.7 4.2 2.9 3.4 4.1 6.8 4.6 1.1 0.8 3.0 2.9 1.5 2.9 0.0 2.1 11.6 3.2 0.2 0.0 2.8 53.6 0.7 1.6 2.4 0.0 10.9 51.7 4.4 0.7 6.5 0.5 1.0 0.0 4.4 1.8 0.0 10.3 0.0 29.8 0.3 2.0 7.6 14.2 122.7 2.8 15.6 1.8 227.7 14.8 1.8 0.0 141.8 200.8 2.5 0.0 6.0 0.5 1.9 0.0 0.2 3.8 1.4 0.0 1.6 4.2 1.6 4.3 0.4 0.6 1.0 0.7 10.6 0.1 0.6 ARHGEF10L "FLJ10521, KIAA1626" ENSG00000074964 "Rho guanine nucleotide exchange factor 10 like" Q9HCE6 1 17539698-17697874 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 41 "classical monocyte: 18.8;intermediate monocyte: 18.0;myeloid DC: 13.4;non-classical monocyte: 4.8" "Group enriched" "Detected in many" 48 "dendritic cells: 13.4;monocytes: 18.8" "Cell line enhanced" "Detected in many" "Hep G2: 26.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026426, HPA026440, HPA028115" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Vesicles, Cytosol" "HPA026426: AB_10599487, HPA026440: AB_10599422, HPA028115: AB_10602285" "unprognostic (4.34e-2)" "unprognostic (1.35e-1)" "unprognostic (1.13e-2)" "unprognostic (2.59e-1)" "unprognostic (1.03e-1)" "prognostic favorable (8.13e-5)" "unprognostic (3.61e-2)" "unprognostic (7.90e-2)" "unprognostic (2.10e-2)" "unprognostic (1.75e-3)" "unprognostic (1.94e-3)" "unprognostic (5.83e-2)" "prognostic favorable (5.65e-4)" "unprognostic (4.11e-2)" "unprognostic (1.66e-1)" "unprognostic (8.17e-2)" "unprognostic (5.21e-3)" 22.2 10.5 11.9 11.4 10.9 1.7 16.5 38.7 11.4 24.2 13.8 29.4 15.9 16.2 4.6 28.1 16.0 11.9 30.2 10.3 12.2 32.5 87.5 13.0 4.5 19.4 18.5 10.4 43.9 17.0 7.9 5.9 19.4 18.4 12.9 4.0 25.9 19.5 66.2 40.9 21.7 8.7 10.9 9.7 20.8 3.7 17.7 1.6 18.0 35.5 4.3 24.6 21.7 9.3 8.0 9.1 11.3 3.9 19.1 6.3 7.6 5.4 10.6 6.3 5.3 9.5 23.6 0.0 9.8 10.2 8.8 6.0 1.6 2.9 1.2 0.2 2.9 0.0 9.5 26.9 4.2 0.0 0.0 8.5 5.5 3.9 1.1 12.7 1.2 0.0 0.0 0.2 17.8 7.7 0.0 0.2 4.9 12.2 0.0 0.0 4.5 3.0 13.4 16.4 16.5 12.2 4.2 2.9 12.3 3.2 11.0 9.5 0.0 5.5 6.5 6.5 2.3 0.0 2.5 0.0 8.5 0.2 3.0 0.0 18.8 0.0 0.0 18.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.3 0.0 4.8 0.0 0.0 7.6 11.9 10.9 38.7 11.4 10.3 12.2 19.4 18.5 19.4 10.9 17.7 9.3 1.3 3.2 7.4 82.6 1.0 5.7 5.3 7.2 5.2 16.1 13.7 12.3 36.4 20.0 13.9 31.3 2.1 0.7 0.1 41.6 9.8 19.8 15.9 3.4 4.2 2.1 37.8 2.7 16.7 20.3 0.6 8.5 17.9 6.5 0.0 3.9 2.5 43.7 26.0 10.1 23.8 45.5 8.2 8.6 26.4 8.9 5.0 18.6 3.6 19.7 9.6 14.6 0.0 24.6 7.1 11.7 24.9 6.8 0.2 5.9 13.6 18.3 9.4 5.4 13.1 10.8 18.3 11.9 1.6 8.0 8.7 1.0 0.6 0.3 46.1 12.1 ARL8B "ARL10C, FLJ10702, Gie1" ENSG00000134108 "ADP ribosylation factor like GTPase 8B" Q9NVJ2 3 5122249-5180911 "Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Langerhans cells: 249.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038759, HPA040515, HPA045924" Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA038759: AB_2676193, HPA040515: AB_2677017, HPA045924: AB_2679500" "unprognostic (1.37e-2)" "unprognostic (1.22e-1)" "unprognostic (3.90e-2)" "unprognostic (3.59e-1)" "unprognostic (1.12e-1)" "unprognostic (3.08e-1)" "prognostic unfavorable (3.68e-6)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (2.21e-2)" "unprognostic (6.27e-3)" "unprognostic (1.96e-1)" "prognostic favorable (4.84e-6)" "unprognostic (5.90e-3)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (1.95e-2)" 41.7 51.1 53.6 36.1 58.4 59.7 42.4 55.4 73.2 39.5 38.3 33.8 30.7 45.1 39.8 65.8 31.1 38.7 55.2 59.7 58.6 53.8 43.9 43.6 38.7 57.2 54.3 38.9 27.5 48.1 0.1 49.8 59.2 45.0 34.8 34.3 28.6 41.8 50.7 54.8 34.3 47.0 60.3 33.9 34.1 32.2 59.5 35.8 62.1 59.9 47.5 49.7 0.3 61.7 49.5 44.1 38.5 20.7 118.4 103.8 71.7 67.8 75.5 64.0 75.8 33.6 44.9 52.6 29.4 65.7 141.4 30.6 61.9 60.1 73.2 58.3 35.8 86.2 34.3 48.4 162.5 73.9 97.0 96.7 179.5 80.9 56.2 67.4 72.2 47.2 76.6 55.0 96.2 45.1 63.0 56.1 36.2 44.6 65.2 43.5 52.2 46.7 63.9 73.8 22.1 41.9 57.7 112.5 96.2 42.7 66.0 219.7 61.6 66.5 55.8 91.9 62.3 50.8 88.0 143.9 94.4 102.7 54.9 42.9 37.8 24.5 18.8 33.0 22.4 19.8 19.6 18.8 31.7 16.7 20.0 20.0 17.0 22.1 27.4 14.2 20.3 27.7 53.6 58.4 55.4 73.2 59.7 58.6 57.2 54.3 59.2 60.3 59.5 61.7 35.8 80.1 63.7 52.9 42.9 128.1 60.5 40.4 74.6 23.3 44.4 31.4 55.6 31.5 45.2 35.0 10.4 42.4 30.4 38.9 19.6 37.2 33.7 45.9 39.8 35.9 13.1 35.1 61.6 37.6 80.1 48.7 33.6 88.5 56.4 25.3 19.2 42.4 97.8 8.4 68.3 19.5 24.4 68.3 249.6 42.0 23.0 109.3 55.2 47.8 103.3 37.2 23.7 47.7 86.0 61.5 26.7 33.8 45.4 71.5 23.2 46.1 40.6 22.7 72.3 31.7 45.7 34.5 24.0 109.5 164.7 173.1 36.8 23.8 16.6 123.3 ARPIN "C15orf38, MGC61550" ENSG00000242498 "Actin related protein 2/3 complex inhibitor" Q7Z6K5 15 89895006-89912952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 5.3;intermediate monocyte: 2.9;myeloid DC: 4.5" "Group enriched" "Detected in many" 6 "dendritic cells: 4.5;monocytes: 5.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA040513, HPA047173, HPA052278" Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "HPA040513: AB_2677015, HPA047173: AB_2679969, HPA052278: AB_2681783" "unprognostic (2.63e-1)" "unprognostic (1.09e-1)" "unprognostic (4.35e-2)" "unprognostic (5.01e-2)" "unprognostic (2.08e-2)" "unprognostic (1.27e-1)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (7.46e-2)" "unprognostic (2.67e-3)" "unprognostic (1.75e-2)" "unprognostic (1.57e-1)" "prognostic favorable (4.19e-4)" "unprognostic (8.47e-2)" "unprognostic (1.36e-1)" "unprognostic (2.23e-1)" "unprognostic (6.62e-3)" 10.6 4.7 9.3 7.0 10.1 0.9 8.4 11.2 8.5 11.4 5.4 15.0 14.5 11.9 13.9 10.3 11.5 8.1 8.1 8.1 9.7 7.5 5.2 11.9 4.6 10.8 9.3 14.7 40.0 12.9 5.0 8.6 9.7 12.6 16.7 9.5 9.0 11.3 9.5 12.2 16.9 11.5 9.3 7.7 8.0 6.0 10.5 3.3 8.7 8.1 5.4 9.5 10.7 10.4 13.9 18.5 18.6 12.3 10.9 14.9 3.5 12.8 9.5 8.5 9.6 2.6 18.8 0.1 6.3 11.6 3.4 6.4 0.1 12.6 7.6 0.1 4.6 0.1 22.1 3.5 7.2 0.1 1.2 9.7 12.2 10.2 2.1 6.5 14.9 0.1 0.1 0.6 11.1 2.8 0.0 0.3 7.5 11.6 2.1 0.0 0.5 0.1 4.5 13.2 0.6 6.1 28.1 11.4 14.5 9.9 22.4 3.8 10.3 15.8 17.6 20.3 6.4 0.3 0.1 0.2 13.1 0.1 5.9 0.5 5.3 0.1 0.1 2.9 0.3 0.1 0.1 0.0 4.5 0.2 0.1 0.1 0.7 0.2 0.4 0.3 0.0 1.3 9.3 10.1 11.2 8.5 8.1 9.7 10.8 9.3 9.7 9.3 10.5 10.4 14.8 25.6 21.0 0.0 1.0 0.0 16.2 0.0 11.4 9.5 11.1 10.3 10.2 22.8 8.1 16.5 12.5 16.1 0.3 19.0 3.9 10.0 33.3 13.0 11.8 13.2 12.2 1.7 0.0 15.8 17.5 13.6 9.2 10.9 6.3 15.7 13.2 13.4 24.4 5.0 0.0 18.3 0.0 26.6 0.0 109.0 15.2 18.5 0.0 0.0 23.0 14.0 0.0 0.0 0.0 12.8 23.8 17.0 0.2 12.5 50.6 19.2 5.1 15.4 13.1 18.3 11.9 20.2 5.7 18.2 0.0 6.7 0.8 6.4 20.6 12.1 ASGR1 CLEC4H1 ENSG00000141505 "Asialoglycoprotein receptor 1" P07306 17 7173431-7179564 "Predicted intracellular proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1092.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 1107.9" "Cancer enriched" "Detected in many" 90 "liver cancer: 131.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 115.2;intermediate monocyte: 55.5;myeloid DC: 41.2" "Group enriched" "Detected in many" 8 "dendritic cells: 41.2;monocytes: 115.2" "Cell line enriched" "Detected in some" 29 "Hep G2: 493.2" "Region enriched" "Detected in all" 9 "cerebellum: 44.1" "Not detected" "Not detected" "HPA011954, HPA012852" Enhanced Supported "Vesicles,Cell Junctions" "Secreted to blood" NA NA 10000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Cell Junctions" "HPA011954: AB_1845079, HPA012852: AB_1845080" "unprognostic (3.56e-3)" "unprognostic (3.57e-1)" "unprognostic (8.76e-2)" "unprognostic (4.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-2)" "unprognostic (5.37e-2)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (8.55e-5)" "unprognostic (1.55e-1)" "unprognostic (8.33e-11)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (1.73e-3)" "unprognostic (4.46e-3)" 2.6 1.5 7.7 3.7 7.8 2.5 1.8 17.0 10.9 1.6 7.0 1.2 2.2 1.3 0.6 1.7 1.8 2.9 1.1 7.9 7.6 1.4 1092.3 3.9 1.3 8.0 8.2 1.1 0.9 7.0 2.9 0.5 8.3 1.7 0.5 4.8 0.9 0.3 1.5 4.4 1.4 1.3 6.0 4.8 1.4 26.5 7.8 0.4 5.8 0.4 0.3 1.7 1.5 8.7 0.3 0.7 9.2 4.2 0.0 0.2 0.8 0.8 0.9 0.9 1.6 16.8 0.5 0.3 1.1 0.2 0.4 0.2 0.3 0.2 0.4 0.3 0.8 1.2 1.4 493.2 0.1 0.8 1.7 1.2 0.2 0.5 0.1 0.6 8.4 7.4 1.1 0.6 0.5 0.4 0.7 1.2 1.7 0.2 0.4 0.9 3.5 0.2 0.1 0.7 0.6 3.5 0.7 0.3 0.6 1.5 0.5 0.2 1.2 0.9 3.4 0.7 0.4 0.2 0.3 0.5 0.6 0.4 0.3 10.0 115.2 0.4 0.2 55.5 1.1 0.5 0.2 0.2 41.2 0.5 0.3 0.4 3.3 0.5 14.9 1.8 0.3 36.7 7.7 7.8 17.0 10.9 7.9 7.6 8.0 8.2 8.3 6.0 7.8 8.7 6.0 0.0 4.7 2.9 2.6 3.2 1.7 2.0 3.4 37.8 5.6 6.0 1.5 55.8 2.0 3.7 160.6 3.6 2.9 1.4 3.9 0.9 235.4 4.2 3.6 13.2 15.6 16.8 4.6 0.2 3.7 1.9 3.6 16.5 0.0 5.1 27.5 1107.9 39.9 15.2 4.8 2.3 2.0 97.4 11.9 115.8 2.5 52.6 0.0 1.9 77.2 3.6 0.0 2.0 0.6 0.3 1.3 1.2 0.0 0.9 0.2 6.8 1.6 42.3 0.0 0.8 1.9 6.5 9.7 9.9 4.8 12.4 1.4 1.6 1.3 2.4 ASGR2 CLEC4H2 ENSG00000161944 "Asialoglycoprotein receptor 2" P07307 17 7101322-7115700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "liver: 840.7" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 878.6" "Cancer enriched" "Detected in many" 66 "liver cancer: 214.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "classical monocyte: 110.0;myeloid DC: 64.1" "Group enriched" "Detected in many" 51 "dendritic cells: 64.1;monocytes: 110.0" "Cell line enriched" "Detected in some" 9 "Hep G2: 528.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014899, HPA015998" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 14000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Plasma membrane" "HPA014899: AB_1845085, HPA015998: AB_1845084" "unprognostic (6.76e-2)" "unprognostic (7.45e-7)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (4.99e-2)" "unprognostic (1.16e-3)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (9.74e-2)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (9.35e-4)" "unprognostic (1.54e-3)" "unprognostic (6.95e-2)" "unprognostic (1.86e-1)" "unprognostic (7.31e-2)" 1.5 0.3 0.8 7.9 1.0 7.0 0.5 0.9 1.3 0.4 1.3 0.5 0.3 0.3 0.1 0.5 0.6 17.6 0.5 0.8 1.0 1.2 840.7 2.5 0.9 1.0 1.1 0.2 0.5 0.1 0.2 0.5 1.2 0.4 0.4 0.0 0.5 0.2 0.2 5.2 0.6 1.3 1.0 6.8 0.5 0.5 1.4 0.5 0.3 0.1 1.0 2.0 0.4 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 62.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 528.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.3 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 1.0 110.0 0.8 0.1 11.2 0.2 0.0 0.0 0.0 64.1 0.0 0.1 0.0 1.7 0.1 0.1 1.6 0.3 31.8 0.8 1.0 0.9 1.3 0.8 1.0 1.0 1.1 1.2 1.0 1.4 1.2 0.0 0.0 5.1 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 150.2 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 0.4 0.0 0.0 1.3 7.1 19.6 1.9 0.0 0.2 0.1 0.0 0.1 2.5 0.0 16.1 878.6 8.4 0.0 0.1 0.1 0.0 41.1 7.7 0.7 0.0 19.6 0.0 0.0 15.3 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 6.6 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.3 0.4 1.4 0.0 0.0 0.1 ATF5 ENSG00000169136 "Activating transcription factor 5" Q9Y2D1 19 49928702-49933935 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "liver: 2479.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 1412.6" "Cancer enriched" "Detected in all" 7 "liver cancer: 200.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 24.0;intermediate monocyte: 22.4;myeloid DC: 14.3;plasmacytoid DC: 38.5" "Group enriched" "Detected in all" 9 "dendritic cells: 38.5;monocytes: 24.0" "Cell line enhanced" "Detected in all" "HDLM-2: 313.2;Karpas-707: 523.4;THP-1: 452.4;U-266/84: 715.6;U-698: 316.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030187 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm Cytosol "HPA030187: AB_10601666" "unprognostic (2.09e-2)" "prognostic favorable (1.14e-4)" "unprognostic (9.38e-3)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.52e-1)" "unprognostic (6.70e-2)" "unprognostic (3.11e-2)" "unprognostic (2.36e-1)" "unprognostic (4.83e-2)" "unprognostic (2.96e-3)" "prognostic unfavorable (3.39e-7)" "unprognostic (3.06e-2)" "unprognostic (8.06e-2)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" 40.7 61.4 11.7 31.7 11.6 21.4 35.6 10.7 15.2 14.9 9.3 19.6 28.3 16.2 9.8 18.0 22.9 14.4 17.3 12.2 14.7 26.1 2479.9 17.0 23.3 14.5 17.0 14.1 29.1 10.0 14.7 12.3 15.7 23.2 10.3 12.5 21.1 10.3 30.6 17.7 23.2 10.2 13.6 27.3 24.5 44.3 12.4 13.1 118.7 9.5 20.0 24.4 14.3 15.3 68.5 47.3 17.8 12.0 18.3 15.5 17.8 48.6 40.8 49.4 30.2 35.7 36.5 60.7 24.3 28.6 34.0 24.2 22.7 20.0 23.5 313.2 22.6 41.7 14.8 27.4 12.5 162.7 113.6 108.3 31.5 36.5 8.5 12.2 21.4 132.6 38.1 523.4 24.7 64.3 23.5 35.9 8.8 18.6 62.6 194.2 19.1 24.9 56.6 90.9 28.2 20.1 113.2 47.8 34.9 6.6 39.2 452.4 36.6 95.5 61.3 11.3 49.8 13.8 715.6 316.2 75.1 63.6 36.4 0.4 24.0 1.0 1.4 22.4 2.0 1.6 1.4 1.7 14.3 0.8 1.2 1.8 3.6 3.2 6.0 38.5 1.9 4.7 11.7 11.6 10.7 15.2 12.2 14.7 14.5 17.0 15.7 13.6 12.4 15.3 16.3 12.8 11.9 2.6 41.7 22.6 12.3 11.1 39.9 3.8 31.9 29.3 7.4 38.6 9.4 16.5 6.2 33.9 23.5 22.0 13.7 13.1 260.8 36.5 17.4 21.1 21.5 64.2 1.2 29.8 19.4 27.3 34.1 35.3 6.3 27.1 40.0 1412.6 82.5 92.5 1.8 21.0 2.0 59.4 172.3 134.3 13.4 51.2 40.9 2.8 259.9 17.4 8.2 0.5 1.6 20.0 20.6 16.6 118.1 24.8 49.0 47.9 9.6 7.5 13.1 18.0 24.2 15.0 11.3 37.7 24.0 35.6 15.1 23.4 23.4 18.4 ATG7 "APG7L, DKFZp434N0735, GSA7" ENSG00000197548 "Autophagy related 7" O95352 3 11272309-11557665 "Predicted intracellular proteins, Transporters" "Autophagy, Biological rhythms, Protein transport, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 160.0;Excitatory neurons: 178.7;Inhibitory neurons: 176.4;Late spermatids: 119.1;Microglial cells: 132.1;Oligodendrocytes: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 60.1;classical monocyte: 136.6;eosinophil: 88.4;intermediate monocyte: 79.4;myeloid DC: 82.4;neutrophil: 107.4;non-classical monocyte: 60.8" "Group enriched" "Detected in all" 5 "dendritic cells: 82.4;granulocytes: 107.4;monocytes: 136.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007639, CAB018771" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 33000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Plasma membrane" "CAB018771: AB_2062165, HPA007639: AB_1845162" "unprognostic (3.97e-2)" "unprognostic (2.83e-2)" "prognostic favorable (9.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.79e-1)" "unprognostic (5.19e-2)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.82e-1)" "unprognostic (2.40e-1)" "unprognostic (1.80e-3)" "unprognostic (2.30e-2)" "unprognostic (2.67e-1)" "prognostic favorable (9.55e-4)" "unprognostic (1.61e-1)" "unprognostic (3.65e-2)" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" 16.8 13.5 11.2 25.0 13.1 47.6 18.0 7.3 21.8 14.5 17.0 17.3 13.0 14.9 16.7 16.7 18.7 16.6 10.8 12.4 9.5 13.7 13.2 20.9 23.9 15.0 15.0 12.2 10.9 21.2 7.5 21.0 13.1 11.6 19.2 10.3 12.2 11.9 13.0 18.0 13.8 20.0 12.4 16.4 14.4 22.5 15.4 13.1 13.0 13.5 25.0 20.3 12.0 21.3 48.5 37.1 16.7 9.2 28.0 36.7 80.4 44.5 56.8 43.1 49.9 16.0 42.5 22.1 26.5 39.2 45.1 14.5 18.3 62.0 73.8 19.8 23.5 16.0 33.6 19.6 36.9 46.8 50.8 38.0 28.2 83.6 52.0 45.4 60.5 14.0 24.1 17.9 60.6 31.3 13.7 21.3 13.0 22.2 47.9 17.1 19.6 19.9 32.5 34.2 14.6 14.5 31.6 26.4 17.5 20.1 28.8 44.7 42.5 36.0 25.7 23.6 63.2 11.1 31.8 38.1 57.8 43.1 49.9 60.1 136.6 88.4 15.9 79.4 12.3 13.0 12.9 15.1 82.4 12.3 11.7 13.7 107.4 21.3 60.8 14.7 12.4 56.8 11.2 13.1 7.3 21.8 12.4 9.5 15.0 15.0 13.1 12.4 15.4 21.3 6.4 0.0 9.8 160.0 11.4 11.1 7.3 21.6 9.6 18.1 7.4 3.6 4.2 4.3 12.5 7.3 18.8 16.5 7.9 8.3 7.9 12.3 44.2 10.6 9.5 14.6 11.4 9.5 178.7 12.9 16.8 11.0 10.7 13.2 14.7 12.4 19.6 9.0 57.6 20.2 176.4 7.6 22.4 25.8 12.1 119.1 10.2 28.8 3.6 132.1 30.6 8.1 13.4 99.0 137.2 17.4 7.3 9.8 10.8 6.4 8.4 6.8 16.5 12.5 6.6 11.7 10.6 22.4 11.9 9.8 7.7 19.2 10.1 9.9 7.6 7.4 ATP6V1F "ATP6S14, VATF, Vma7" ENSG00000128524 "ATPase H+ transporting V1 subunit F" Q16864 7 128862856-128865847 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1054.6;Hofbauer cells: 1132.8;Proximal tubular cells: 1076.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009529, HPA048700, HPA062011" Supported NA NA 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" "CAB009529: AB_2290237, HPA048700: AB_2680498, HPA062011: AB_2684656" "unprognostic (1.70e-1)" "unprognostic (1.61e-2)" "unprognostic (2.14e-2)" "unprognostic (3.26e-2)" "unprognostic (2.99e-2)" "unprognostic (8.46e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.28e-3)" "unprognostic (2.70e-1)" "unprognostic (1.04e-2)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "prognostic favorable (2.49e-5)" "unprognostic (2.20e-1)" "unprognostic (2.43e-1)" "unprognostic (1.36e-2)" "unprognostic (7.33e-2)" 133.3 160.7 275.6 106.2 290.1 210.4 122.3 272.7 368.6 126.5 250.2 104.6 74.7 95.3 61.7 223.0 98.3 104.2 183.3 294.8 300.1 307.0 84.2 140.0 139.9 280.1 275.3 89.0 106.8 163.5 141.0 104.6 286.0 103.0 56.6 110.6 129.3 81.6 169.3 170.1 97.0 71.2 269.5 119.6 114.4 212.2 284.3 119.6 84.6 154.7 103.7 123.1 146.6 277.4 305.6 345.1 151.2 323.2 297.6 236.8 86.9 151.2 201.3 246.8 267.2 257.0 179.8 287.6 156.5 175.7 367.7 163.9 224.5 250.1 91.9 312.6 364.2 220.1 211.4 256.4 344.1 227.1 400.8 278.2 340.0 284.7 163.4 188.9 238.1 257.9 534.3 297.3 276.3 403.1 381.0 494.3 201.9 190.6 281.4 168.7 110.1 467.5 315.5 240.3 286.6 197.3 214.1 796.5 363.7 156.6 184.4 284.9 253.0 303.5 65.3 409.5 236.2 333.5 326.9 372.0 600.4 315.5 263.6 370.2 697.1 489.2 244.6 475.1 238.0 343.7 247.6 239.7 508.9 348.5 235.8 238.6 203.1 243.6 324.7 288.3 317.3 886.1 275.6 290.1 272.7 368.6 294.8 300.1 280.1 275.3 286.0 269.5 284.3 277.4 129.3 28.9 62.8 17.3 140.1 237.6 202.5 378.9 136.6 111.4 162.0 190.1 157.6 127.2 230.7 331.1 37.5 171.8 119.8 97.3 1054.6 241.0 574.0 128.6 96.3 163.1 113.2 63.1 27.0 222.2 289.0 155.1 78.5 131.0 275.1 114.0 124.6 112.0 1132.8 545.1 34.6 108.7 585.9 320.6 378.7 898.9 164.4 456.1 254.3 16.9 285.8 230.4 190.5 11.6 26.2 253.9 93.0 127.9 136.8 224.7 212.0 1076.3 200.2 96.4 85.5 69.7 168.9 399.6 102.0 328.4 326.6 401.4 136.3 184.5 98.9 362.7 BCKDHA "MSU, OVD1A" ENSG00000248098 "Branched chain keto acid dehydrogenase E1 subunit alpha" P12694 19 41397808-41425002 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 26.2;Gastric mucus-secreting cells: 23.4;Plasma cells: 25.0;Squamous epithelial cells: 27.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036640 Supported NA NA 7700 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "HPA036640: AB_10671964" "unprognostic (4.50e-2)" "unprognostic (6.85e-2)" "unprognostic (1.14e-1)" "unprognostic (8.58e-3)" "unprognostic (1.26e-2)" "prognostic favorable (9.37e-4)" "unprognostic (2.41e-2)" "unprognostic (8.55e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-2)" "unprognostic (1.12e-2)" "unprognostic (1.53e-1)" "prognostic favorable (5.33e-10)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.27e-5)" "unprognostic (9.66e-2)" 33.8 78.4 32.0 19.3 35.5 32.4 25.2 37.0 39.3 24.6 37.0 20.9 19.9 17.9 14.1 65.1 28.8 15.4 90.4 32.5 35.1 44.3 110.0 22.4 24.5 34.4 33.8 25.4 46.1 56.3 24.0 19.0 36.2 23.8 15.0 21.7 40.9 23.1 110.0 31.8 18.7 12.7 33.9 24.4 52.5 27.1 35.7 27.0 41.7 122.0 21.2 21.7 31.9 40.0 42.7 75.1 14.2 44.1 22.2 12.8 17.1 11.9 25.3 24.4 29.9 18.2 36.0 34.6 23.7 15.1 11.0 17.1 15.0 25.9 12.1 36.0 41.0 27.1 35.2 21.3 51.5 25.5 17.7 27.6 37.6 16.9 38.2 36.0 45.0 50.9 25.9 68.9 17.6 41.5 28.0 20.0 12.8 61.1 21.1 27.1 22.8 89.6 29.8 19.8 32.5 38.6 39.6 84.7 34.1 12.1 45.4 81.0 29.3 22.2 23.0 12.0 22.0 131.9 55.1 34.1 81.8 56.6 24.6 61.4 149.4 59.7 49.5 123.9 56.7 46.0 47.0 49.1 154.6 49.5 43.2 44.9 46.4 82.4 95.5 62.6 63.9 125.6 32.0 35.5 37.0 39.3 32.5 35.1 34.4 33.8 36.2 33.9 35.7 40.0 0.6 0.0 13.1 4.9 10.0 0.3 0.1 2.6 26.2 0.2 1.5 0.4 0.1 1.5 5.3 5.5 0.0 1.9 0.9 3.8 3.9 14.7 0.7 0.5 0.6 2.4 6.1 15.5 5.8 11.8 1.7 3.7 23.4 0.7 5.1 0.4 2.5 2.4 2.7 0.0 6.2 7.6 8.2 2.2 0.8 0.9 0.6 6.6 3.6 3.7 12.4 0.4 5.2 4.0 5.7 8.4 3.8 0.4 25.0 0.2 6.7 2.3 1.2 1.2 0.0 0.2 3.6 1.8 0.9 27.2 0.9 2.1 6.3 0.3 7.3 0.1 BCKDK ENSG00000103507 "Branched chain keto acid dehydrogenase kinase" O14874 16 31106107-31112791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 95.9;granulocytes: 89.7;monocytes: 115.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017995, HPA056067" Supported Supported Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA017995: AB_1845309, HPA056067: AB_2683024" "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (6.94e-2)" "unprognostic (5.20e-2)" "unprognostic (5.39e-2)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (5.47e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.24e-2)" "unprognostic (2.66e-3)" "unprognostic (4.85e-2)" "unprognostic (3.93e-2)" "unprognostic (1.00e-1)" "unprognostic (4.97e-2)" 32.3 56.4 18.4 19.2 18.6 14.5 29.0 17.4 23.8 25.1 18.0 31.4 16.0 27.7 16.7 29.4 24.8 17.9 78.6 18.8 17.8 43.8 76.4 21.7 15.6 20.6 20.7 27.5 70.5 22.9 16.4 15.3 19.3 29.3 12.5 6.3 47.0 21.8 81.3 45.4 24.1 19.5 17.1 30.2 42.0 17.4 18.5 9.8 22.4 69.7 13.6 30.2 24.6 17.5 47.5 49.1 27.1 41.8 32.8 32.5 31.1 40.4 46.3 57.3 55.9 32.1 29.1 41.5 58.9 47.5 28.0 31.4 19.3 65.6 36.5 34.4 60.1 45.2 32.6 59.5 57.5 23.5 41.9 48.3 26.2 49.2 40.6 52.6 62.4 31.1 23.4 39.4 87.7 75.8 22.9 32.4 23.0 20.5 39.1 45.8 39.6 78.8 44.3 30.1 42.1 38.7 31.3 72.4 24.6 22.9 44.5 24.6 41.1 44.2 26.1 45.8 32.2 44.5 15.7 15.1 50.3 33.7 42.6 58.1 115.0 85.2 17.7 97.6 17.2 22.8 16.5 13.9 95.9 19.0 13.6 16.1 89.7 22.8 71.2 19.3 24.5 53.1 18.4 18.6 17.4 23.8 18.8 17.8 20.6 20.7 19.3 17.1 18.5 17.5 27.2 19.2 18.1 5.9 20.0 18.5 24.6 61.0 22.2 11.6 30.9 27.6 39.1 25.8 28.5 20.2 0.0 55.4 9.0 31.5 80.3 68.6 2.5 14.6 24.3 29.2 19.9 16.4 5.1 78.0 71.1 24.9 25.5 20.0 33.0 35.4 25.4 43.8 93.0 11.8 4.4 22.3 42.7 44.5 50.3 7.8 20.8 53.1 12.4 1.9 79.3 22.6 9.2 4.5 4.5 54.8 48.4 25.6 51.7 30.9 66.9 95.2 19.6 9.8 46.0 18.4 33.2 25.8 14.1 25.7 27.4 69.4 12.1 45.5 26.0 27.0 BLVRB "FLR, SDR43U1" ENSG00000090013 "Biliverdin reductase B" P30043 19 40447765-40465764 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 625.2" "Cell type enhanced" "Detected in all" "Erythroid cells: 3131.8;Hofbauer cells: 1099.2;Proximal enterocytes: 864.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 465.2" "Group enriched" "Detected in all" 7 "dendritic cells: 343.3;monocytes: 465.2" "Cell line enhanced" "Detected in many" "A549: 506.6;K-562: 506.8;OE19: 451.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041698, HPA041937" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "Nucleoplasm, Vesicles, Plasma membrane" "HPA041698: AB_10796781, HPA041937: AB_10794308" "unprognostic (1.86e-1)" "unprognostic (1.14e-2)" "unprognostic (4.23e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (1.20e-2)" "unprognostic (8.56e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" "unprognostic (2.02e-1)" "unprognostic (5.11e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" 115.7 76.8 46.6 48.2 46.9 625.2 93.8 49.4 61.0 86.2 52.1 78.5 75.1 59.0 20.5 188.8 69.3 50.9 125.6 44.5 48.0 103.1 266.2 102.8 58.9 56.0 48.6 66.7 73.2 46.1 25.2 52.1 58.5 74.3 30.3 5.5 89.4 42.2 210.4 83.9 72.2 31.7 49.8 166.7 138.4 10.2 52.3 27.5 64.5 94.1 25.3 81.0 96.5 53.4 227.9 506.6 7.3 77.7 73.7 70.2 57.3 28.0 88.7 39.3 75.4 103.4 203.8 74.3 212.3 56.3 126.8 73.1 30.4 64.6 10.5 123.8 20.0 114.9 73.4 62.4 169.8 1.6 32.2 69.2 119.4 52.4 34.2 40.1 41.8 27.4 506.8 137.0 51.0 359.2 6.1 7.2 1.9 451.4 133.8 54.0 23.4 120.3 50.9 146.5 0.4 10.5 84.5 224.5 84.4 13.2 221.5 17.6 39.2 99.4 103.9 156.4 15.9 71.7 92.1 28.5 259.1 46.2 39.0 45.5 465.2 18.0 29.2 220.9 27.0 58.2 24.3 24.5 343.3 37.5 24.7 19.3 58.4 27.4 117.7 75.8 37.3 259.4 46.6 46.9 49.4 61.0 44.5 48.0 56.0 48.6 58.5 49.8 52.3 53.4 74.6 221.2 164.5 9.4 34.4 129.4 348.5 337.9 103.6 11.2 93.8 143.0 130.5 164.5 184.2 97.5 6.2 84.9 39.5 343.6 266.1 234.2 10.0 56.5 46.3 51.1 44.9 3131.8 5.2 267.3 94.7 112.5 280.3 83.1 43.1 31.0 57.1 680.8 1099.2 10.1 5.1 223.5 158.7 627.7 165.4 23.6 124.2 286.7 144.1 13.1 219.8 88.0 32.0 2.0 5.6 260.4 464.0 94.0 25.7 229.7 864.3 488.3 139.1 13.5 32.9 65.4 146.0 2.6 4.0 160.3 130.4 74.7 34.5 34.7 191.0 260.5 BNIP3L "BNIP3a, Nix" ENSG00000104765 "BCL2 interacting protein 3 like" O60238 8 26383054-26505636 "Cancer-related genes, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 913.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015652, CAB025371" Enhanced Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "Nuclear speckles" "CAB025371: , HPA015652: AB_1845406" "unprognostic (1.02e-1)" "unprognostic (2.90e-1)" "unprognostic (2.00e-1)" "unprognostic (8.36e-2)" "unprognostic (6.24e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (2.02e-1)" "unprognostic (2.06e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.92e-5)" "unprognostic (8.72e-3)" "unprognostic (5.16e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (7.59e-3)" 130.6 53.4 42.7 37.2 60.4 192.6 77.9 55.6 62.0 63.9 38.9 39.6 22.2 52.8 66.3 48.3 50.5 54.7 63.2 50.0 49.6 79.4 45.4 62.9 39.4 60.7 54.0 119.7 20.1 55.1 25.4 104.5 58.4 44.4 28.2 146.5 44.1 64.4 38.9 71.5 28.4 51.3 46.6 40.7 28.9 68.6 48.8 39.9 41.9 31.7 52.1 48.9 49.5 80.8 90.6 33.8 79.1 53.9 214.5 134.0 66.8 89.0 259.9 81.9 179.6 15.3 42.7 27.7 82.5 169.0 113.4 44.8 39.6 114.5 270.0 17.8 21.8 114.9 32.0 26.9 119.3 10.3 191.1 162.5 89.2 92.9 55.3 269.2 106.2 66.9 52.6 65.0 173.7 39.1 72.7 38.5 26.2 56.7 36.6 38.4 99.9 55.6 85.3 58.3 83.9 74.4 43.2 8.8 70.0 85.9 43.7 21.7 140.4 152.2 64.6 96.2 20.5 93.2 46.0 36.8 232.6 20.6 35.1 334.9 298.3 182.9 39.5 154.8 34.9 68.4 58.4 43.3 166.9 78.0 89.3 65.5 369.0 47.6 104.1 38.0 86.1 239.3 42.7 60.4 55.6 62.0 50.0 49.6 60.7 54.0 58.4 46.6 48.8 80.8 118.3 86.6 157.4 28.7 72.2 98.8 56.0 231.7 82.6 142.5 90.6 85.3 34.0 50.1 126.4 103.0 33.3 33.2 55.6 32.7 49.0 115.4 194.1 173.5 140.8 101.2 120.6 913.9 50.6 39.1 166.5 179.9 38.7 341.2 120.9 96.5 167.0 32.2 132.1 82.4 39.4 46.8 118.0 221.3 300.4 206.7 320.3 233.6 106.7 30.0 165.0 406.4 32.0 29.1 75.8 154.1 39.8 347.5 64.6 83.6 44.0 306.4 107.6 64.0 144.7 59.1 183.9 154.4 110.7 65.4 126.6 162.5 67.0 117.6 27.6 79.3 BPI BPIFD1 ENSG00000101425 "Bactericidal permeability increasing protein" P17213 20 38304150-38337505 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "bone marrow: 1503.7" "Group enriched" "Detected in some" 8 "Early spermatids: 201.8;Late spermatids: 220.6;Proximal tubular cells: 99.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "classical monocyte: 14.5;neutrophil: 7.1" "Group enriched" "Detected in many" 17 "granulocytes: 7.1;monocytes: 14.5" "Cell line enhanced" "Detected in single" "HL-60: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA061284 Enhanced "Secreted to blood" NA NA 7290000 78000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA061284: AB_2684465" "unprognostic (9.30e-4)" "unprognostic (5.49e-2)" "unprognostic (1.97e-1)" "unprognostic (2.26e-1)" "unprognostic (1.44e-1)" "unprognostic (1.56e-1)" "unprognostic (4.50e-2)" "unprognostic (1.98e-1)" "unprognostic (3.07e-2)" "unprognostic (1.14e-1)" "unprognostic (2.60e-2)" "unprognostic (1.50e-1)" "unprognostic (8.83e-6)" "unprognostic (2.66e-4)" "unprognostic (9.29e-2)" "unprognostic (2.32e-2)" "unprognostic (9.47e-3)" 0.5 0.2 0.1 0.1 0.2 1503.7 0.6 0.1 0.4 2.6 0.2 0.2 0.0 0.7 1.0 0.1 0.4 0.5 0.5 0.1 0.2 3.4 0.8 3.7 0.3 0.2 0.2 1.7 0.0 0.0 0.6 0.5 0.2 0.4 0.0 0.0 1.4 1.2 0.1 1.8 0.1 0.2 0.2 13.0 0.1 17.1 0.2 3.7 0.2 0.2 0.2 0.2 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 14.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.1 0.0 0.6 0.0 0.0 9.8 0.1 0.2 0.1 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.0 0.0 1.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.3 0.3 0.4 0.0 0.4 3.7 0.0 0.0 0.0 0.0 9.8 0.0 201.8 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.7 20.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 220.6 17.7 1.3 1.8 0.0 7.1 0.0 1.0 0.0 0.0 0.0 0.0 18.4 0.0 0.0 0.0 99.7 0.3 0.0 0.0 0.2 0.4 2.1 1.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 3.1 1.8 4.2 7.5 7.2 13.0 3.6 4.7 5.2 2.7 2.7 6.8 3.2 3.1 2.2 4.0 3.7 1.9 3.0 3.6 4.1 2.0 5.6 3.2 10.3 5.6 5.0 2.8 2.8 5.9 2.8 3.8 6.0 2.4 7.4 8.2 3.2 1.6 4.2 6.0 5.1 3.9 3.7 3.9 3.6 13.0 5.5 14.5 7.8 3.7 11.2 2.8 2.4 10.8 44.1 69.1 37.8 30.1 6.0 13.4 36.6 50.6 21.5 41.9 39.3 42.3 33.4 100.8 9.1 19.0 49.0 49.5 51.9 28.3 69.5 46.9 38.0 48.1 54.0 37.1 1.3 86.0 39.9 3.8 4.5 63.1 20.0 10.6 22.3 46.6 73.7 42.2 39.7 30.0 72.0 27.8 20.5 29.1 18.7 49.0 79.8 40.8 15.4 42.1 25.8 27.4 38.8 12.5 19.4 25.5 33.9 39.6 13.8 37.2 29.6 49.0 53.2 20.1 51.2 75.5 29.6 49.6 39.4 6.8 14.7 2.2 1.5 4.7 1.5 1.2 1.5 1.2 10.9 2.1 1.3 1.5 11.3 1.5 2.0 1.7 0.5 17.5 4.2 7.2 4.7 5.2 3.6 4.1 5.6 5.0 6.0 3.7 5.5 10.8 5.0 0.0 2.8 9.4 5.8 2.9 4.5 1.9 1.2 10.3 4.4 5.2 10.1 5.7 3.5 1.8 22.9 12.8 8.1 6.2 0.0 3.0 11.9 14.0 6.3 4.7 0.0 42.5 3.0 1.1 18.2 7.4 6.1 4.2 8.2 38.2 5.3 18.3 10.1 11.8 4.4 7.5 0.0 3.9 2.8 8.0 2.5 6.4 0.0 4.7 4.9 2.4 5.2 3.0 18.7 1.7 2.4 1.5 16.6 2.3 1.1 1.0 10.0 22.8 6.6 13.7 5.5 105.8 73.5 8.2 2.3 4.0 4.7 9.7 12.7 3.4 BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 139.8;intestine: 48.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.8;Macrophages: 33.3;monocytes: 80.1;Proximal enterocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 257.7;neutrophil: 292.7" "Group enriched" "Detected in many" 95 "dendritic cells: 78.9;granulocytes: 292.7;monocytes: 257.7" "Cell line enhanced" "Detected in many" "THP-1: 76.0;TIME: 40.4;U-937: 52.5;WM-115: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" NA NA 190000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" 21.2 2.7 1.9 13.7 2.1 139.8 9.4 2.1 4.7 11.0 1.6 8.3 48.6 6.3 2.9 4.6 7.9 18.2 19.1 2.1 2.0 17.0 8.5 12.7 7.1 1.9 1.4 9.3 3.1 1.7 1.3 13.7 2.2 3.7 9.7 1.0 3.9 4.6 2.7 5.0 29.3 9.7 0.8 18.6 3.2 2.7 3.0 3.9 4.9 6.8 3.5 16.8 7.4 3.3 0.6 10.5 1.2 1.0 28.8 7.0 1.6 21.0 2.1 20.4 22.2 0.3 12.1 0.8 1.9 12.2 0.6 0.3 3.3 0.5 17.2 0.8 0.7 5.6 0.8 0.6 6.7 7.2 15.1 5.7 1.5 12.9 1.0 0.9 3.0 5.0 0.7 0.5 12.5 0.3 2.3 4.3 2.7 0.9 2.2 0.8 1.8 0.5 0.5 0.6 1.4 4.3 0.4 0.7 14.2 1.2 0.5 76.0 40.4 0.6 1.0 7.9 1.1 0.6 0.2 0.7 2.7 52.5 44.8 41.8 257.7 20.8 1.1 97.4 1.7 2.2 0.9 0.8 78.9 0.9 1.1 0.7 292.7 0.4 73.9 26.6 1.0 109.8 1.9 2.1 2.1 4.7 2.1 2.0 1.9 1.4 2.2 0.8 3.0 3.3 5.4 3.2 3.7 1.3 0.3 4.6 0.8 0.1 1.8 0.6 1.2 2.0 1.5 2.8 1.0 1.8 0.0 16.0 5.5 3.7 1.9 4.4 4.4 8.0 9.9 3.8 1.2 2.5 0.7 2.5 24.0 22.5 0.0 16.2 15.9 20.6 6.4 2.1 40.8 0.0 0.7 8.1 0.0 26.3 11.5 1.2 3.1 33.3 14.2 3.7 80.1 0.6 3.1 0.5 3.6 1.1 11.9 2.2 0.4 0.6 79.0 9.6 3.0 0.2 6.6 3.9 15.5 2.5 1.4 1.7 3.0 7.1 1.8 1.4 23.2 3.3 C11orf71 FLJ20010 ENSG00000180425 "Chromosome 11 open reading frame 71" Q6IPW1 11 114391443-114400511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 139.0" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2360.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063943, HPA074787" Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA063943: AB_2685157, HPA074787: AB_2686712" "unprognostic (1.24e-1)" "unprognostic (2.53e-2)" "unprognostic (1.42e-2)" "prognostic favorable (6.94e-4)" "unprognostic (7.35e-2)" "unprognostic (4.53e-2)" "unprognostic (1.83e-1)" "unprognostic (2.30e-3)" "unprognostic (1.58e-1)" "unprognostic (3.04e-3)" "unprognostic (1.39e-2)" "unprognostic (2.85e-2)" "prognostic favorable (7.01e-9)" "unprognostic (5.68e-2)" "unprognostic (5.43e-2)" "unprognostic (1.87e-1)" "unprognostic (1.17e-2)" 5.8 10.7 11.8 5.1 13.7 3.7 7.6 12.3 13.8 5.5 10.8 6.9 7.6 5.1 22.6 4.3 7.1 4.4 9.3 11.7 13.9 13.9 22.1 5.9 6.7 14.0 16.7 7.2 8.7 8.9 13.4 3.7 13.2 8.5 6.2 15.9 9.8 5.7 15.0 9.4 7.5 2.9 12.2 9.4 7.3 139.0 12.7 8.9 12.4 15.2 4.7 4.6 4.1 16.0 1.2 3.9 4.2 13.6 6.2 3.6 2.9 0.6 1.7 1.7 1.5 3.0 23.6 6.8 7.8 1.0 8.1 6.3 2.8 2.9 2.1 7.5 1.6 5.1 3.2 6.9 5.9 3.0 5.5 5.9 3.2 2.2 6.7 1.9 2.1 10.8 5.1 6.0 3.2 5.5 5.5 4.6 2.2 5.5 2.5 3.9 3.4 17.3 3.8 3.0 11.6 4.6 15.3 1.8 2.4 4.4 11.5 1.6 2.1 0.4 5.9 4.6 1.2 5.8 10.1 5.2 0.9 6.9 1.7 15.9 15.4 10.3 8.8 9.8 5.5 5.9 5.7 6.0 9.3 8.3 9.5 9.9 12.3 12.1 11.9 12.0 7.1 10.1 11.8 13.7 12.3 13.8 11.7 13.9 14.0 16.7 13.2 12.2 12.7 16.0 12.7 3.2 13.4 5.2 8.0 2.7 15.7 6.3 8.6 10.3 18.3 15.9 19.0 0.0 6.2 5.5 4.2 16.1 6.4 15.0 82.2 15.7 589.6 21.2 8.1 8.7 18.1 7.2 4.7 18.9 3.4 9.5 18.8 12.8 6.3 14.1 0.0 0.0 11.5 13.5 5.6 16.7 10.2 0.0 4.1 2360.8 13.1 13.6 5.4 2.8 11.2 31.5 7.2 4.0 18.5 10.5 15.5 9.1 17.2 9.2 33.0 78.6 18.9 14.1 6.6 7.6 8.0 70.6 9.9 10.4 2.6 14.6 7.4 19.6 12.7 11.4 C15orf48 "COXFA4L3, MIR147BHG, NMES1" ENSG00000166920 "Chromosome 15 open reading frame 48" Q9C002 15 45430579-45448761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 924.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2962.4;Exocrine glandular cells: 2020.8;Langerhans cells: 2043.7;Pancreatic endocrine cells: 3493.6;Paneth cells: 2254.4;Proximal enterocytes: 2942.0;Undifferentiated cells: 1875.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;intermediate monocyte: 1.6;myeloid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 70.9;CAPAN-2: 128.8;GAMG: 126.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA012943 Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA012943: AB_2668774" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (7.83e-2)" "unprognostic (1.17e-1)" "unprognostic (9.74e-3)" "unprognostic (1.48e-3)" "unprognostic (1.28e-3)" "unprognostic (1.59e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-3)" "unprognostic (5.95e-2)" "unprognostic (8.86e-2)" "unprognostic (2.37e-1)" "unprognostic (6.51e-2)" "unprognostic (1.39e-1)" "unprognostic (3.66e-1)" 2.2 0.3 0.5 98.5 0.5 88.0 30.7 0.4 3.2 38.9 0.7 863.4 61.9 5.3 0.2 172.4 6.8 45.9 0.8 0.5 0.5 5.8 6.0 11.5 5.7 0.6 0.4 0.7 13.0 0.1 0.5 46.4 1.3 13.9 924.2 3.6 23.0 11.5 0.4 69.9 341.3 31.3 0.4 2.3 107.6 128.1 1.0 7.0 5.2 0.2 84.8 38.9 46.6 0.6 70.9 18.1 0.2 0.3 0.9 0.0 2.7 3.5 25.1 4.6 12.7 2.9 128.8 0.2 3.1 0.4 126.2 1.8 2.3 0.9 10.7 7.0 1.9 0.0 0.2 0.5 11.2 0.1 29.1 1.3 1.2 22.9 0.0 0.0 0.0 0.5 0.1 0.5 0.6 3.5 0.1 1.8 0.1 31.4 0.3 0.0 0.4 0.4 2.7 5.7 0.1 0.6 4.1 8.0 0.3 14.0 1.4 1.6 0.6 0.4 1.6 1.0 0.9 2.1 1.2 0.4 1.9 0.7 0.5 0.0 1.3 0.1 0.0 1.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.8 0.0 0.2 0.1 0.0 0.8 0.5 0.5 0.4 3.2 0.5 0.5 0.6 0.4 1.3 0.4 1.0 0.6 5.5 16.0 15.0 0.3 20.4 66.4 20.2 846.0 1.2 0.5 143.2 111.9 1.0 188.8 1117.6 5.5 0.0 286.2 7.4 2962.4 3.9 811.3 188.3 29.2 11.0 11.6 645.1 0.0 0.2 2020.8 450.3 16.4 250.2 67.7 33.0 0.2 1.4 3.7 398.4 114.4 0.1 1408.8 270.6 25.9 2043.7 235.4 7.2 388.4 58.7 0.0 489.4 0.7 1.0 0.5 0.4 3493.6 2254.4 7.5 4.1 200.5 2942.0 18.7 700.9 1.2 0.0 1.2 75.2 567.9 124.4 10.6 61.2 165.5 13.9 0.1 1875.4 633.4 C1orf43 "DKFZp586G1722, NICE-3" ENSG00000143612 "Chromosome 1 open reading frame 43" Q9BWL3 1 154206696-154220637 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010725 Approved Supported Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA010725: AB_1078341" "unprognostic (3.90e-2)" "unprognostic (1.22e-2)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.87e-2)" "unprognostic (6.15e-3)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.72e-1)" "unprognostic (2.78e-1)" "unprognostic (2.64e-2)" "unprognostic (3.51e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (2.89e-1)" "unprognostic (1.75e-2)" "unprognostic (1.23e-1)" 126.7 131.9 148.0 72.6 160.4 77.3 119.7 158.9 168.6 90.5 145.1 109.3 118.4 80.7 115.3 107.7 100.5 86.7 179.7 141.7 158.3 187.7 222.0 106.3 82.0 153.0 152.6 77.1 149.7 149.6 85.7 67.6 151.6 94.9 121.2 135.7 99.1 90.2 477.6 105.8 106.1 90.6 152.4 81.6 117.2 62.0 154.2 92.0 108.7 368.2 99.0 113.9 85.7 169.3 183.5 188.4 156.5 185.1 231.1 230.7 96.2 180.2 309.4 205.0 188.4 127.7 249.8 237.9 268.1 162.9 177.5 182.4 218.5 163.3 147.2 191.1 232.1 184.9 182.6 168.1 357.9 235.4 209.6 187.1 376.6 219.8 449.7 278.6 239.9 262.6 199.1 220.1 268.4 287.5 177.4 212.1 302.3 414.8 282.3 159.8 145.8 435.9 256.0 180.6 254.8 333.5 161.1 420.8 624.9 180.8 416.6 513.5 164.4 157.9 133.6 193.3 229.7 403.5 424.1 227.6 263.4 234.4 430.9 189.9 204.8 134.3 85.9 185.4 102.4 100.3 98.7 93.3 211.5 90.0 102.8 86.8 114.9 83.3 174.6 156.2 154.3 242.7 148.0 160.4 158.9 168.6 141.7 158.3 153.0 152.6 151.6 152.4 154.2 169.3 107.2 115.4 100.8 27.1 92.1 94.2 128.4 155.3 81.4 112.6 132.9 114.4 135.8 128.7 115.4 71.7 29.2 87.2 86.8 106.1 252.4 171.5 247.1 69.6 62.1 105.4 122.0 110.0 27.3 202.0 125.1 80.2 77.5 58.1 62.1 79.5 100.6 146.9 178.9 58.9 30.8 133.9 116.0 162.5 116.1 171.8 65.0 131.5 124.5 16.9 155.4 107.0 64.9 26.2 50.5 162.8 131.6 74.9 104.1 186.1 218.3 262.1 85.7 89.5 72.3 75.8 86.6 70.7 59.2 113.9 100.6 126.1 76.7 117.4 133.6 167.5 C5orf15 "HTGN29, KCT2" ENSG00000113583 "Chromosome 5 open reading frame 15" Q8NC54 5 133955510-133968674 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011951, HPA039165" Uncertain Approved "Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA011951: AB_2668584, HPA039165: AB_10795580" "unprognostic (2.25e-1)" "unprognostic (3.01e-1)" "unprognostic (2.07e-1)" "unprognostic (4.91e-2)" "unprognostic (1.81e-1)" "unprognostic (2.26e-3)" "unprognostic (1.01e-2)" "unprognostic (7.72e-2)" "unprognostic (2.62e-2)" "unprognostic (7.54e-2)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (9.07e-3)" "unprognostic (5.18e-2)" "unprognostic (1.34e-1)" "unprognostic (1.66e-1)" "unprognostic (2.14e-2)" 35.4 49.5 15.5 35.6 16.2 18.6 44.7 16.6 22.9 38.5 24.8 32.4 48.7 35.4 34.4 24.0 48.0 41.3 40.7 15.5 17.1 73.6 80.3 39.9 47.5 16.7 16.6 36.6 26.3 44.7 19.9 58.9 17.2 39.6 33.1 24.5 30.9 25.1 22.3 30.7 48.6 30.5 17.4 37.3 48.8 26.6 15.9 33.9 53.1 22.6 37.0 46.4 19.0 21.3 70.4 51.5 70.5 81.3 101.9 115.9 85.9 71.3 95.4 107.2 178.7 49.9 204.1 49.5 127.4 87.3 108.4 51.1 57.7 104.0 125.6 56.3 87.7 18.7 34.2 63.9 96.1 30.8 79.8 102.2 62.7 84.7 44.7 152.5 45.9 31.3 39.7 57.4 86.7 44.7 35.9 57.9 39.0 34.1 30.8 34.0 72.3 73.8 175.0 53.9 62.8 47.0 71.9 24.2 117.1 126.0 74.9 91.7 42.4 95.6 88.4 39.2 71.8 42.9 44.1 30.3 113.3 72.9 143.6 19.5 31.6 16.8 14.6 34.6 13.7 22.8 16.6 16.0 37.0 24.3 21.1 17.1 16.3 22.0 34.2 26.7 17.3 29.4 15.5 16.2 16.6 22.9 15.5 17.1 16.7 16.6 17.2 17.4 15.9 21.3 18.6 25.6 33.2 12.7 32.3 30.7 39.8 85.7 33.6 22.0 41.3 22.1 17.9 51.5 54.1 49.7 10.4 83.6 19.6 27.1 17.6 73.7 45.6 68.4 34.2 21.2 37.2 17.1 17.1 46.8 71.9 61.1 25.0 32.2 15.2 31.5 23.9 48.5 55.7 5.0 15.6 30.4 81.4 32.8 57.7 7.0 51.3 34.0 64.0 21.5 97.1 27.6 19.6 37.2 35.3 47.9 24.1 39.1 28.8 33.5 51.5 71.8 125.5 26.9 26.3 30.6 36.3 46.8 29.1 23.3 32.5 58.0 21.5 80.6 21.2 22.8 C9orf153 bA507D14.1 ENSG00000187753 "Chromosome 9 open reading frame 153" Q5TBE3 9 86220265-86259657 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 20.8" "Group enriched" "Detected in some" 26 "Early spermatids: 268.6;Late spermatids: 244.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "HeLa: 1.3" "Not detected" "Not detected" HPA079466 Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Nuclear bodies, Plasma membrane" "Nucleoplasm, Vesicles" "HPA079466: " "unprognostic (2.03e-1)" "unprognostic (1.79e-1)" "unprognostic (1.13e-2)" "unprognostic (2.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.30e-3)" "unprognostic (7.49e-2)" "unprognostic (2.75e-2)" "unprognostic (3.37e-1)" "unprognostic (6.85e-2)" "unprognostic (9.70e-2)" "unprognostic (1.49e-1)" "unprognostic (2.01e-6)" "unprognostic (9.43e-2)" "unprognostic (1.92e-1)" "unprognostic (9.64e-2)" "unprognostic (2.10e-1)" 0.1 0.4 0.3 0.4 0.2 2.6 0.2 1.4 0.9 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.2 0.5 0.5 0.6 0.2 0.1 0.1 0.0 0.9 0.6 0.1 0.1 0.6 0.2 0.2 0.0 0.3 0.2 0.1 0.0 0.2 0.3 20.8 0.5 0.1 0.2 0.1 0.0 0.0 0.0 1.3 0.2 0.8 0.0 0.4 0.0 0.4 0.3 0.2 0.0 0.0 0.2 0.0 0.6 0.8 0.2 0.2 0.5 0.2 0.0 0.0 0.1 0.1 0.3 0.0 1.3 0.2 0.1 0.2 0.2 0.1 0.6 0.1 0.0 0.0 0.3 0.9 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.7 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.6 0.1 0.2 0.4 0.1 0.3 0.0 0.1 0.4 0.8 1.6 0.2 0.3 0.6 0.1 0.1 0.1 0.1 1.2 0.2 0.1 0.1 0.5 0.3 0.2 0.2 0.1 1.5 0.3 0.2 1.4 0.9 0.2 0.2 0.5 0.6 0.6 0.0 0.5 1.3 0.3 0.0 0.0 9.8 0.1 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 268.6 0.4 0.5 0.7 0.0 0.0 4.8 0.0 0.1 0.4 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 244.8 2.8 0.1 1.8 1.0 0.1 0.4 2.1 6.6 9.7 0.1 0.0 0.7 0.4 0.3 0.0 0.1 0.0 0.1 0.0 1.3 0.7 1.8 1.9 0.0 0.1 0.1 0.2 0.3 0.1 0.2 CARD19 "bA370F5.1, BinCARD, C9orf89, MGC11115" ENSG00000165233 "Caspase recruitment domain family member 19" Q96LW7 9 93096217-93113283 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 142.0;Pancreatic endocrine cells: 121.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 134.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010921, HPA010990, HPA038297" Approved Supported Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Mitochondria "HPA010921: AB_10670295, HPA010990: AB_2668400, HPA038297: AB_2675938" "unprognostic (7.26e-2)" "unprognostic (1.15e-2)" "unprognostic (2.97e-1)" "unprognostic (2.66e-2)" "prognostic unfavorable (7.47e-5)" "unprognostic (2.22e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.21e-1)" "unprognostic (1.36e-2)" "unprognostic (2.65e-2)" "unprognostic (1.98e-1)" "unprognostic (9.13e-2)" "unprognostic (6.82e-2)" "unprognostic (2.29e-1)" "unprognostic (5.48e-2)" "unprognostic (1.03e-1)" "unprognostic (1.41e-1)" 12.2 13.7 2.5 3.7 2.1 3.2 11.3 4.8 4.5 11.5 3.1 14.4 6.1 12.0 2.6 11.0 10.8 5.8 10.3 1.8 3.4 16.2 10.8 10.9 4.0 4.0 2.9 7.9 5.5 6.1 6.6 3.3 4.9 8.7 3.2 0.1 9.4 4.2 14.2 10.8 9.5 4.2 3.6 10.5 12.9 19.1 3.5 3.1 8.7 5.5 2.6 11.5 11.5 5.9 33.0 31.3 4.1 9.2 5.3 10.1 12.9 26.7 13.0 18.2 8.2 7.8 10.6 7.0 18.3 9.5 15.4 56.0 3.3 21.9 1.5 134.9 12.3 12.4 6.5 18.4 21.1 11.2 11.4 23.5 8.1 13.2 5.2 20.0 21.4 6.1 5.7 13.8 12.4 64.7 12.1 30.0 3.6 21.1 70.8 8.2 20.7 29.4 22.9 12.1 9.8 17.3 14.4 6.9 30.6 0.8 15.6 11.6 21.6 9.3 18.6 17.9 8.4 10.4 10.1 1.5 39.0 11.3 32.4 27.8 37.4 23.6 10.2 30.0 10.5 12.6 10.0 10.9 30.6 7.5 9.0 8.9 40.3 18.4 17.3 11.1 21.7 22.4 2.5 2.1 4.8 4.5 1.8 3.4 4.0 2.9 4.9 3.6 3.5 5.9 29.3 22.4 20.9 0.0 14.4 0.0 52.8 0.0 25.6 12.0 81.2 75.6 0.0 27.1 5.6 16.5 16.7 22.9 25.7 27.7 62.6 76.6 49.5 19.4 26.8 34.1 15.8 7.8 0.0 58.1 34.6 26.2 36.2 20.3 30.3 8.2 41.7 13.9 79.0 5.0 0.0 19.8 0.0 41.3 0.0 15.3 45.7 142.0 0.0 0.0 68.3 21.9 17.5 0.0 0.0 121.6 10.3 43.6 15.0 58.7 38.9 61.7 2.2 29.8 59.2 30.4 31.1 98.7 26.4 27.9 0.0 21.6 34.0 8.5 18.6 71.0 CARD6 CINCIN1 ENSG00000132357 "Caspase recruitment domain family member 6" Q9BX69 5 40841308-40860175 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 23.8;Gastric mucus-secreting cells: 26.5;Pancreatic endocrine cells: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 27.4" "Group enriched" "Detected in all" 5 "dendritic cells: 7.7;granulocytes: 27.4;monocytes: 13.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 20.5;HUVEC TERT2: 34.0;TIME: 36.9" "Low region specificity" "Detected in many" HPA036438 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA036438: AB_10670105" "unprognostic (8.57e-3)" "unprognostic (1.30e-1)" "unprognostic (3.43e-1)" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.40e-2)" "unprognostic (4.15e-2)" "unprognostic (3.12e-2)" "unprognostic (8.97e-2)" "unprognostic (1.50e-2)" "unprognostic (1.49e-1)" "unprognostic (9.37e-2)" "unprognostic (1.00e-1)" "unprognostic (2.93e-2)" "unprognostic (1.11e-2)" "unprognostic (8.88e-3)" 9.0 12.0 1.7 5.5 1.9 3.1 5.8 1.9 1.9 4.8 3.3 2.6 7.8 3.5 1.5 10.6 4.5 11.4 4.4 1.8 2.2 4.8 4.0 9.7 4.8 2.8 2.1 1.8 3.1 2.2 1.7 6.9 2.5 1.9 2.8 0.7 7.5 2.8 2.1 2.4 5.3 4.9 2.5 12.9 12.1 1.3 2.8 2.4 5.3 5.4 4.5 8.4 4.1 2.4 3.4 5.8 0.8 0.1 13.0 20.5 0.1 1.7 3.1 0.2 0.7 0.6 1.2 6.4 10.8 4.0 6.9 2.1 0.3 8.4 0.7 0.6 1.4 7.7 10.8 0.6 4.1 6.3 14.4 13.2 6.7 7.6 1.7 9.5 34.0 0.1 7.9 1.1 3.0 0.1 0.0 6.1 0.1 3.3 1.7 0.1 0.2 6.6 12.6 7.2 0.0 0.0 9.6 2.8 1.5 0.1 0.3 11.5 36.9 1.6 1.4 0.4 2.4 0.3 0.1 0.8 3.0 13.3 5.9 27.4 11.2 4.1 1.2 11.3 1.0 1.0 1.7 1.1 7.7 2.0 1.6 1.2 10.7 1.8 13.9 3.0 3.6 4.5 1.7 1.9 1.9 1.9 1.8 2.2 2.8 2.1 2.5 2.5 2.8 2.4 23.8 0.0 17.5 0.0 3.1 1.7 1.5 6.6 5.2 0.0 2.9 2.0 1.4 11.5 6.4 1.8 0.0 0.7 1.8 0.2 0.0 15.9 0.6 5.7 9.6 20.1 0.0 4.8 0.1 14.0 0.8 10.2 26.5 10.3 13.3 0.4 15.4 3.1 9.2 0.0 0.1 0.4 4.1 16.6 1.8 1.0 3.1 14.1 0.0 4.7 11.2 0.7 2.1 0.5 0.1 21.7 1.2 1.2 0.9 0.4 3.2 0.9 4.4 0.0 0.0 1.1 2.7 0.6 0.2 11.3 2.3 0.5 3.0 8.5 1.2 9.1 CBWD1 ENSG00000172785 "COBW domain containing 1" Q9BRT8 9 121038-179147 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 185.1" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (3.75e-2)" "unprognostic (3.47e-2)" "unprognostic (5.23e-2)" "unprognostic (4.15e-2)" "unprognostic (1.39e-1)" "unprognostic (2.67e-2)" "unprognostic (3.91e-2)" "unprognostic (3.72e-1)" "unprognostic (4.15e-2)" "unprognostic (2.07e-3)" "unprognostic (1.82e-1)" "unprognostic (4.68e-2)" "unprognostic (5.80e-7)" "unprognostic (7.19e-2)" "unprognostic (1.04e-1)" "unprognostic (8.94e-2)" "unprognostic (4.98e-3)" 18.6 34.4 8.7 15.3 9.2 13.0 19.9 10.6 11.1 14.3 13.0 16.9 13.3 13.7 20.8 26.8 14.6 10.6 20.7 9.0 10.2 40.1 26.8 16.1 13.4 9.0 9.0 15.4 30.0 38.3 19.4 22.2 9.2 19.9 15.2 27.5 23.7 12.2 21.8 22.3 14.1 12.2 9.0 16.9 19.1 16.4 9.1 13.2 25.4 17.6 20.1 23.4 17.1 9.9 43.3 16.1 22.7 12.2 29.1 26.2 50.3 22.2 14.6 30.4 23.0 23.4 16.1 39.4 28.3 8.2 18.4 7.3 11.3 21.1 32.4 67.8 38.9 0.4 39.1 72.6 31.5 115.1 17.2 23.5 9.9 7.3 59.0 19.5 32.9 19.7 13.6 84.3 25.2 52.1 25.1 185.1 22.9 37.6 34.6 47.7 34.6 75.8 39.4 120.7 40.8 24.8 45.8 16.8 17.8 55.5 35.6 109.2 34.4 16.0 22.9 20.8 19.7 10.1 14.6 44.6 39.6 60.6 19.2 3.6 65.7 19.3 10.3 75.6 16.9 21.1 18.6 16.8 74.1 15.7 16.2 17.7 10.2 12.8 60.8 19.6 18.1 48.3 8.7 9.2 10.6 11.1 9.0 10.2 9.0 9.0 9.2 9.0 9.1 9.9 19.5 54.5 50.1 8.1 41.2 47.7 29.9 47.6 97.9 50.8 49.4 37.6 51.8 30.0 49.8 35.0 108.4 96.3 17.7 20.4 35.2 79.9 51.7 14.9 10.1 23.0 31.2 44.6 17.0 118.5 41.2 23.0 34.7 11.9 32.8 26.7 20.7 19.0 32.0 38.7 17.1 39.0 50.8 25.1 38.0 16.4 18.0 37.9 32.0 18.7 81.5 32.2 18.6 5.5 16.7 66.9 38.2 13.2 90.0 32.0 49.5 73.6 31.0 63.5 32.9 20.2 27.8 48.6 28.1 83.8 50.6 124.8 23.5 24.1 62.3 24.9 CBWD3 bA561O23.1 ENSG00000196873 "COBW domain containing 3" Q5JTY5 9 68232003-68300035 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042759, HPA042813" Uncertain Approved "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (1.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.95e-1)" "unprognostic (9.71e-3)" "unprognostic (9.99e-2)" "unprognostic (6.38e-2)" "unprognostic (3.44e-2)" "unprognostic (1.79e-2)" "unprognostic (3.54e-2)" "unprognostic (1.81e-1)" "unprognostic (1.05e-2)" "unprognostic (2.05e-2)" "unprognostic (1.05e-3)" "unprognostic (3.77e-2)" "unprognostic (1.67e-1)" "unprognostic (4.43e-3)" "unprognostic (5.16e-4)" 12.2 19.4 7.5 18.8 7.5 13.5 17.3 9.8 9.5 9.8 5.3 14.0 13.0 9.9 7.3 17.2 9.7 6.6 13.0 8.1 8.9 21.2 28.4 10.2 16.9 8.4 7.7 12.0 27.2 8.6 18.4 15.6 8.8 10.5 9.8 18.0 13.5 10.2 17.5 13.1 20.6 8.9 4.4 12.7 17.5 12.3 6.9 12.7 14.3 13.3 13.0 18.8 12.2 10.6 73.0 52.6 25.1 41.2 18.9 6.7 34.3 35.6 14.1 15.2 17.4 15.0 69.4 84.1 33.9 26.1 67.5 86.7 48.0 70.5 39.8 128.2 31.0 31.9 137.8 73.6 24.8 60.9 38.3 15.6 21.3 27.0 35.3 30.5 35.6 93.1 60.4 66.1 22.3 47.4 71.8 81.9 38.5 86.4 88.7 32.6 78.7 94.0 17.3 32.8 40.3 25.7 58.0 36.2 46.3 46.6 26.7 71.5 16.6 22.6 58.1 38.4 70.1 38.3 165.4 102.3 68.8 92.3 41.6 29.8 86.1 66.2 27.8 71.5 24.0 52.5 25.2 28.7 62.0 52.3 27.6 25.5 86.5 16.1 52.0 46.5 37.9 59.8 7.5 7.5 9.8 9.5 8.1 8.9 8.4 7.7 8.8 4.4 6.9 10.6 4.3 25.6 30.0 2.0 15.9 14.5 16.2 6.0 12.0 25.2 14.5 9.7 28.7 7.2 21.0 11.0 29.2 13.2 5.6 9.7 1.9 7.1 4.7 4.0 2.4 9.0 4.2 5.2 10.8 11.6 7.9 8.9 8.6 3.8 12.6 12.4 6.1 8.2 5.0 11.8 8.9 9.1 2.0 11.0 10.1 2.4 5.0 6.8 5.4 6.5 19.7 5.9 8.2 10.1 5.6 8.8 17.4 3.0 20.3 12.6 28.9 7.1 24.1 36.2 6.6 5.3 6.3 16.7 7.8 7.3 21.5 15.5 10.6 7.6 10.7 12.9 CCDC149 DKFZp761B107 ENSG00000181982 "Coiled-coil domain containing 149" Q6ZUS6 4 24806117-24980204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enriched" "Detected in single" 5 "monocytes: 1.5" "Cell line enhanced" "Detected in many" "U-87 MG: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044158, HPA047913" Uncertain Approved Nucleoli NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli "HPA044158: AB_2678840, HPA047913: AB_2680207" "unprognostic (1.68e-1)" "unprognostic (2.43e-1)" "unprognostic (1.09e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.06e-1)" "unprognostic (4.11e-4)" "unprognostic (9.71e-5)" "unprognostic (2.68e-2)" "unprognostic (1.79e-1)" "unprognostic (7.82e-2)" "unprognostic (8.59e-3)" "unprognostic (2.25e-1)" "unprognostic (2.80e-3)" "unprognostic (8.87e-2)" "unprognostic (2.25e-1)" "unprognostic (5.03e-2)" "unprognostic (4.80e-2)" 9.7 5.3 11.0 6.2 12.1 2.0 11.9 7.8 13.1 10.4 7.5 11.1 3.7 10.4 6.3 4.6 10.1 6.8 8.4 12.1 10.7 8.4 8.7 8.9 2.2 9.1 9.2 10.6 19.1 8.1 7.2 8.4 9.2 11.4 5.9 8.5 18.8 6.7 7.0 6.6 5.9 10.2 7.9 4.9 13.1 3.7 12.3 2.5 8.8 7.6 2.2 9.0 7.0 11.5 6.0 2.3 4.8 0.8 7.5 13.4 1.3 8.4 13.4 6.9 7.9 0.1 6.9 0.0 3.9 17.0 7.8 1.1 1.4 1.0 4.5 0.0 0.0 0.0 0.4 0.5 6.2 0.0 0.0 9.3 6.5 4.1 0.0 18.8 5.6 0.0 0.0 1.2 4.2 6.3 0.0 0.1 5.3 0.6 5.3 0.0 0.0 0.4 12.5 4.2 5.3 0.1 3.2 5.5 17.8 5.1 9.3 13.8 12.0 10.0 0.9 7.5 7.3 0.1 0.0 0.0 30.6 1.4 6.8 0.0 1.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.5 0.2 0.0 0.5 11.0 12.1 7.8 13.1 12.1 10.7 9.1 9.2 9.2 7.9 12.3 11.5 14.3 0.0 9.5 23.5 0.4 6.2 7.2 2.7 6.8 11.9 11.7 6.9 5.7 5.7 3.7 7.3 10.4 7.1 0.1 2.3 0.0 6.6 1.1 7.4 6.6 13.6 1.8 2.7 30.2 10.4 1.5 8.1 6.6 7.8 0.0 8.3 10.4 6.4 12.2 5.0 39.8 11.9 0.0 9.7 2.1 1.7 10.8 8.1 8.8 16.9 6.7 9.1 0.0 27.6 20.9 8.7 5.6 11.7 1.1 11.0 0.7 2.3 3.1 11.6 6.6 12.5 9.7 1.6 2.8 1.7 3.1 10.7 0.7 2.0 5.2 6.7 CCL1 "I-309, P500, SCYA1, SISe, TCA3" ENSG00000108702 "C-C motif chemokine ligand 1" P22362 17 34360328-34363233 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 2.2;lymphoid tissue: 1.2" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;granulocytes: 8.9;Late spermatids: 1.6;T-cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 38 "HMC-1: 702.6" HPA049861 Uncertain "Secreted to blood" NA NA 84400 "Cluster 25: Monocytes - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA049861: AB_2680919" "unprognostic (6.52e-2)" "unprognostic (4.81e-3)" "unprognostic (5.84e-2)" "unprognostic (5.01e-1)" "unprognostic (6.04e-1)" "unprognostic (2.71e-1)" "unprognostic (1.37e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 702.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.4 0.8 0.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 CCL2 "GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF" ENSG00000108691 "C-C motif chemokine ligand 2" P13500 17 34255218-34257203 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 756.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1152.5;Ductal cells: 3382.2;Exocrine glandular cells: 919.2;Prostatic glandular cells: 889.0;Skeletal myocytes: 994.7;Smooth muscle cells: 1507.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 7.5;eosinophil: 3.0" "Group enriched" "Detected in many" 6 "granulocytes: 3.0;monocytes: 7.5" "Group enriched" "Detected in many" 4 "BJ hTERT+: 1902.2;HMC-1: 2427.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 9.9;spinal cord: 39.4" "CAB013676, HPA019163" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 323000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" Vesicles "CAB013676: , HPA019163: AB_1846179" "unprognostic (6.43e-2)" "unprognostic (4.14e-2)" "unprognostic (4.78e-2)" "unprognostic (5.57e-2)" "unprognostic (2.37e-3)" "unprognostic (8.64e-2)" "unprognostic (2.78e-2)" "unprognostic (7.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" "unprognostic (9.33e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (1.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.81e-1)" "unprognostic (4.92e-2)" 390.9 129.8 15.6 167.2 15.1 96.5 76.8 14.7 26.8 20.4 24.4 169.5 41.2 30.2 15.0 47.1 85.6 256.5 305.8 16.0 21.1 229.5 161.1 405.1 78.4 32.7 16.5 19.3 141.6 34.6 70.5 39.1 21.9 153.1 103.5 11.5 47.0 45.4 19.6 40.3 80.3 150.7 21.4 73.2 121.2 12.1 43.3 142.7 84.4 47.0 16.6 756.1 36.3 25.3 0.1 15.3 40.4 0.0 110.7 94.5 0.3 116.6 1902.2 243.3 516.8 7.1 0.2 0.3 90.4 27.6 3.8 64.0 4.3 0.1 122.9 0.6 0.9 0.2 13.5 0.0 3.5 0.4 2427.9 105.9 0.0 50.6 2.9 162.6 112.4 0.0 6.5 20.2 0.0 0.0 0.7 19.6 5.8 0.0 0.4 0.6 3.3 20.9 354.7 0.0 0.1 8.1 0.3 6.0 3.3 108.4 4.6 2.5 6.4 129.0 5.7 3.6 0.7 1.2 0.5 0.1 75.7 37.6 84.3 0.0 7.5 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 1.6 15.6 15.1 14.7 26.8 16.0 21.1 32.7 16.5 21.9 21.4 43.3 25.3 218.3 182.7 126.5 2.0 3.6 568.6 866.2 595.3 1152.5 0.1 23.5 50.9 29.5 92.9 120.7 138.0 0.0 2.7 2.2 0.0 0.0 3382.2 0.0 8.4 37.8 577.2 0.0 0.0 0.7 919.2 3.6 840.5 5.6 11.4 353.0 0.1 50.3 0.4 439.1 0.0 0.1 0.0 6.1 8.9 408.5 0.4 12.2 593.1 213.5 8.4 37.8 13.8 0.0 0.0 0.1 781.2 0.0 1.5 2.9 889.0 0.0 67.7 27.7 0.7 131.5 994.7 1507.0 0.4 0.3 13.0 222.8 4.5 44.3 1.7 0.1 40.6 CCL8 "HC14, MCP-2, SCYA8" ENSG00000108700 "C-C motif chemokine ligand 8" P80075 17 34319435-34321402 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Smooth muscle cells: 104.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 6 "monocytes: 3.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.1;BJ hTERT+ SV40 Large T+ RasG12V: 1.0;EFO-21: 2.1;HSkMC: 3.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 32000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (7.51e-2)" "unprognostic (3.20e-1)" "unprognostic (1.90e-2)" "unprognostic (4.03e-2)" "unprognostic (8.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (9.97e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.05e-7)" "unprognostic (1.39e-1)" "unprognostic (1.88e-2)" "unprognostic (5.65e-2)" "unprognostic (3.41e-2)" 17.5 4.7 0.4 5.1 0.4 1.8 6.2 0.4 0.9 1.5 0.5 18.1 14.1 7.3 1.9 3.5 1.3 8.8 2.7 0.4 0.4 7.7 3.2 7.1 3.9 0.6 0.4 1.4 1.1 4.8 0.5 7.1 0.6 2.2 16.4 0.0 1.9 1.3 0.4 0.5 17.0 9.3 1.8 2.9 2.9 3.1 1.1 12.5 2.3 7.0 0.5 13.7 0.3 0.6 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.1 0.0 1.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.4 0.9 0.4 0.4 0.6 0.4 0.6 1.8 1.1 0.6 21.5 0.0 0.0 0.0 0.1 4.2 0.3 0.5 0.0 0.0 0.9 1.1 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 10.5 0.9 7.5 9.6 0.0 0.0 0.0 2.0 0.0 16.4 0.0 1.6 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 3.5 18.6 2.2 0.0 12.7 5.4 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.3 104.3 0.0 0.0 0.0 5.4 0.1 0.8 0.7 0.0 0.1 CCNY "C10orf9, CBCP1, CFP1" ENSG00000108100 "Cyclin Y" Q8ND76 10 35247025-35572669 "Predicted intracellular proteins" "Cell cycle, Cell division, Wnt signaling pathway" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Late spermatids: 3651.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 26.4" "Group enriched" "Detected in all" 5 "dendritic cells: 7.8;granulocytes: 26.4;monocytes: 23.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036290 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA036290: AB_10600860" "unprognostic (1.25e-2)" "unprognostic (1.48e-1)" "unprognostic (4.30e-2)" "unprognostic (2.23e-3)" "unprognostic (1.30e-1)" "unprognostic (4.65e-1)" "prognostic unfavorable (6.75e-5)" "unprognostic (3.37e-2)" "unprognostic (6.15e-3)" "unprognostic (4.06e-2)" "unprognostic (2.94e-1)" "unprognostic (1.10e-1)" "unprognostic (2.74e-2)" "unprognostic (1.31e-1)" "unprognostic (3.77e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" 28.6 21.9 35.1 21.2 37.1 35.9 23.7 31.6 35.1 21.8 24.8 28.4 21.5 28.4 26.9 20.5 22.2 22.7 33.1 37.0 32.4 24.8 31.0 25.9 23.4 32.0 33.6 25.2 20.6 17.9 15.5 38.7 31.9 18.3 20.0 19.3 17.0 20.1 25.5 19.3 22.2 25.7 32.3 24.4 26.3 81.2 35.5 22.5 29.6 22.9 21.0 25.4 17.3 33.4 52.3 22.2 29.3 28.2 41.6 56.5 38.2 27.4 27.7 26.0 24.9 32.4 51.7 33.2 38.1 44.1 22.7 27.1 26.3 34.6 27.7 105.0 17.3 62.0 16.0 42.4 45.8 22.7 28.3 40.3 48.1 39.9 27.1 57.6 63.3 38.3 49.1 27.3 51.6 33.2 39.9 19.6 11.2 29.6 46.2 33.0 54.4 20.7 33.2 24.6 25.8 39.3 21.5 42.7 38.6 25.4 36.9 41.8 75.5 32.1 38.6 49.4 23.9 18.3 16.6 24.4 56.0 46.6 15.1 1.7 23.4 5.2 3.3 6.5 3.6 3.1 3.2 3.5 7.8 2.4 3.2 3.6 26.4 2.9 3.4 4.0 2.3 7.6 35.1 37.1 31.6 35.1 37.0 32.4 32.0 33.6 31.9 32.3 35.5 33.4 102.2 32.1 25.9 91.1 23.4 26.9 14.1 29.0 13.6 43.5 30.2 28.7 33.1 41.5 32.1 38.6 20.9 12.0 35.2 25.8 5.9 16.5 709.0 29.5 37.2 59.8 52.8 12.4 205.5 27.8 18.1 34.4 20.4 33.4 16.5 35.3 32.5 85.3 28.9 48.8 130.0 29.0 26.4 80.4 46.9 3651.5 41.3 56.6 16.0 192.0 89.3 62.4 24.7 167.9 445.2 27.9 19.2 38.7 11.7 27.7 31.5 23.1 28.5 39.6 6.6 56.0 26.5 33.8 40.2 17.1 29.5 9.4 26.2 43.2 28.6 20.9 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD1D ENSG00000158473 "CD1d molecule" P15813 1 158178030-158186427 "Cancer-related genes, CD markers, Predicted membrane proteins" "Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 18.2;liver: 15.3;lymphoid tissue: 23.9" "Cell type enhanced" "Detected in many" "B-cells: 22.2;Kupffer cells: 54.6;Macrophages: 40.8;monocytes: 45.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 139.0;intermediate monocyte: 63.8;myeloid DC: 139.3" "Group enriched" "Detected in many" 8 "dendritic cells: 139.3;monocytes: 139.0" "Cell line enhanced" "Detected in some" "HHSteC: 10.2;JURKAT: 49.4;MOLT-4: 13.6;THP-1: 8.8" "Low region specificity" "Detected in all" "CAB016107, HPA072662" Enhanced Supported "Endoplasmic reticulum" NA NA 880000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" "CAB016107: AB_626960, HPA072662: AB_2686545" "unprognostic (8.67e-2)" "unprognostic (6.99e-2)" "unprognostic (2.48e-1)" "unprognostic (1.48e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (3.85e-1)" "unprognostic (9.67e-3)" "unprognostic (2.37e-1)" "unprognostic (3.52e-1)" "unprognostic (2.23e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (9.31e-3)" "unprognostic (2.35e-1)" "unprognostic (2.32e-2)" "unprognostic (3.38e-1)" 2.7 2.0 0.1 7.5 0.2 3.1 2.0 0.1 0.4 1.5 0.7 4.4 7.4 2.2 0.5 0.8 2.1 1.8 3.3 0.1 0.2 2.2 15.3 3.4 4.7 0.3 0.2 0.6 1.9 0.3 1.0 0.4 0.3 2.2 2.9 0.3 1.1 0.7 1.1 0.3 18.2 2.3 0.1 23.9 2.3 2.5 0.2 9.4 2.7 0.6 3.0 1.8 1.0 0.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.3 0.0 0.0 3.5 0.0 6.0 0.0 0.0 0.1 0.2 0.0 0.0 10.2 0.1 0.0 3.9 0.6 0.0 0.7 0.0 0.0 49.4 0.0 0.0 0.0 0.0 13.6 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 8.8 0.0 0.0 2.0 0.0 0.0 0.3 0.0 0.3 0.0 3.7 0.4 0.2 139.0 0.4 0.2 63.8 0.5 17.6 0.1 0.1 139.3 13.4 0.1 0.0 7.2 0.3 11.0 1.4 0.2 80.7 0.1 0.2 0.1 0.4 0.1 0.2 0.3 0.2 0.3 0.1 0.2 0.4 9.4 0.0 3.6 0.0 22.2 0.3 0.5 0.8 0.6 0.7 0.1 0.9 0.7 2.8 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.4 5.6 0.4 2.0 2.4 2.4 1.7 0.0 0.0 0.2 0.5 0.0 0.3 1.3 0.1 3.3 6.3 11.3 1.7 0.2 2.0 0.0 54.6 0.8 2.1 0.0 40.8 0.0 0.0 45.4 0.6 1.0 0.0 0.0 0.0 6.4 0.0 3.7 0.1 7.3 0.1 0.0 0.3 0.0 1.2 0.4 1.0 2.1 0.0 0.1 0.1 0.6 0.1 4.5 0.1 CD209 "CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1" ENSG00000090659 "CD209 molecule" Q9NNX6 19 7739993-7747564 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 34.2;placenta: 22.8" "Group enriched" "Detected in some" 4 "Kupffer cells: 15.6;Langerhans cells: 14.7;Macrophages: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "classical monocyte: 1.4;intermediate monocyte: 1.4;myeloid DC: 1.2" "Group enriched" "Detected in many" 4 "dendritic cells: 1.2;monocytes: 1.4" "Cell line enriched" "Detected in single" 14 "THP-1: 3.3" "CAB032436, CAB033831" Supported "Intracellular and membrane" NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB032436: AB_639039, CAB033831: AB_1121347" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (5.36e-3)" "unprognostic (1.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-2)" "unprognostic (3.83e-2)" "unprognostic (2.10e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (6.17e-2)" "unprognostic (1.09e-1)" 34.2 3.9 0.3 8.6 0.6 0.4 4.4 1.3 3.0 4.0 5.7 10.5 14.3 1.4 1.0 4.8 2.5 8.6 4.5 0.3 0.7 2.1 3.3 4.9 18.1 1.0 0.6 1.0 1.0 0.8 0.7 22.8 0.8 0.8 13.9 0.1 2.1 1.9 0.9 1.4 19.3 10.6 0.9 2.4 4.1 2.1 0.6 5.4 1.4 1.5 2.3 20.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 1.4 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.4 0.3 0.6 1.3 3.0 0.3 0.7 1.0 0.6 0.8 0.9 0.6 0.8 0.3 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 15.6 14.7 0.3 0.0 12.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.1 CD36 "FAT, GP3B, GP4, GPIV, SCARB3" ENSG00000135218 "CD36 molecule" P16671 7 80369575-80679277 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Transport" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1533.6" "Cell type enhanced" "Detected in many" "Adipocytes: 3219.2;Cardiomyocytes: 623.1;Hofbauer cells: 1369.8;Sertoli cells: 696.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 962.6;intermediate monocyte: 270.6;myeloid DC: 507.1" "Group enriched" "Detected in all" 46 "dendritic cells: 507.1;monocytes: 962.6" "Group enriched" "Detected in some" 4 "ASC diff: 322.6;HEL: 158.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 16.9" "HPA002018, CAB025866, HPA071026" Enhanced Enhanced "Golgi apparatus" NA NA 5300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB025866: , HPA002018: AB_1078464, HPA071026: AB_2732170" "unprognostic (7.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.06e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (9.35e-2)" "unprognostic (2.64e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.84e-3)" "prognostic unfavorable (4.47e-4)" "unprognostic (7.05e-3)" "unprognostic (4.87e-2)" "unprognostic (2.73e-3)" 1533.6 24.6 3.4 51.7 2.5 148.2 540.4 1.6 2.0 11.6 2.7 40.5 113.6 8.7 38.2 19.6 40.5 84.0 540.9 2.6 6.9 7.0 80.8 131.2 18.8 22.0 21.2 4.0 31.2 25.0 2.0 413.3 15.7 5.0 40.9 0.3 31.9 8.6 248.5 28.6 119.7 39.4 14.0 309.9 31.2 7.7 24.0 22.1 69.1 381.6 7.2 22.2 13.4 3.9 0.0 0.0 1.0 0.2 322.6 3.3 0.7 0.9 10.7 0.1 0.1 0.0 0.0 0.1 0.6 1.4 0.3 0.1 4.3 0.5 0.1 0.6 0.4 158.1 0.5 25.7 0.2 0.1 0.1 31.0 12.6 0.1 0.2 7.7 0.9 0.0 5.8 0.0 1.8 0.2 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.5 0.5 0.1 0.9 1.3 0.8 0.6 0.3 2.7 11.1 19.3 0.4 0.5 0.5 0.6 0.3 0.2 0.8 0.4 0.1 54.3 41.8 12.3 962.6 3.7 1.9 270.6 2.1 3.6 0.6 0.6 507.1 0.5 0.8 0.4 15.8 5.9 72.0 128.3 1.5 692.4 3.4 2.5 1.6 2.0 2.6 6.9 22.0 21.2 15.7 14.0 24.0 3.9 3219.2 6.4 63.1 0.0 7.9 7.4 0.2 3.0 0.6 0.2 189.9 24.8 623.1 4.3 9.8 7.3 0.0 10.1 55.0 0.0 0.0 0.2 11.7 5.0 5.9 303.3 0.0 419.5 6.3 0.0 11.1 69.6 1.1 38.4 15.2 0.6 406.2 9.0 1369.8 0.0 2.2 0.6 8.2 153.7 67.3 3.9 0.6 159.6 16.0 17.8 255.2 0.0 7.2 0.5 1.3 0.1 0.0 0.0 4.2 0.8 9.9 0.4 1.2 0.3 696.8 33.1 452.1 4.6 0.7 0.8 4.7 18.3 5.9 1.9 0.2 0.3 CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 137.6" "Cell type enhanced" "Detected in many" "Adipocytes: 321.5;Endothelial cells: 309.2;Hepatic stellate cells: 162.8;Kupffer cells: 156.4;Macrophages: 102.4;monocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 346.0;TIME: 442.2;U-937: 593.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" 81.4 11.9 2.7 43.5 2.6 16.4 41.0 2.8 6.5 23.9 6.5 13.8 9.8 17.8 6.1 19.0 23.4 39.7 34.3 2.7 3.5 25.6 16.3 64.6 14.0 5.4 4.3 6.2 13.2 10.8 6.6 137.6 5.4 11.3 12.1 1.4 9.7 10.9 24.2 12.2 14.5 43.5 4.0 23.4 13.0 4.6 7.1 9.3 21.4 34.4 10.6 41.3 12.8 3.5 0.2 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 346.0 0.0 0.9 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.9 0.2 27.8 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 105.3 442.2 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 593.5 0.1 0.0 25.8 0.4 0.3 16.8 0.0 0.0 0.2 0.1 9.1 0.0 0.0 0.0 27.8 0.1 7.5 1.2 0.5 9.9 2.7 2.6 2.8 6.5 2.7 3.5 5.4 4.3 5.4 4.0 7.1 3.5 321.5 3.2 7.4 0.0 2.4 15.0 1.0 0.0 6.2 0.0 1.0 1.8 14.3 5.7 3.7 0.0 0.0 0.2 5.0 0.0 0.0 0.5 0.4 0.4 0.7 309.2 0.0 1.3 0.0 0.0 0.5 9.8 0.5 0.4 5.1 0.0 162.8 1.9 19.9 0.0 0.2 0.0 0.0 156.4 52.5 0.8 1.8 102.4 8.8 4.7 131.8 0.2 6.2 0.0 0.1 0.1 0.0 27.8 2.1 4.1 0.0 0.3 3.0 0.1 19.7 5.7 8.0 0.0 0.2 1.6 10.1 0.4 2.4 3.0 0.0 4.0 CDC42EP1 "Borg5, CEP1, MSE55" ENSG00000128283 "CDC42 effector protein 1" Q00587 22 37560480-37569405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 245.6;Exocrine glandular cells: 226.0;Pancreatic endocrine cells: 266.2;Urothelial cells: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 7.3;intermediate monocyte: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 10 "dendritic cells: 2.4;monocytes: 7.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006379, HPA076536" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA006379: AB_1078486, HPA076536: " "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.44e-1)" "unprognostic (3.79e-3)" "unprognostic (5.82e-2)" "unprognostic (4.06e-2)" "unprognostic (4.38e-2)" "unprognostic (5.57e-2)" "unprognostic (9.45e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-2)" "unprognostic (3.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.09e-3)" 76.3 91.2 55.7 16.7 107.5 1.6 58.0 89.9 73.3 68.2 17.6 43.7 31.1 70.7 4.1 93.1 61.0 40.8 53.8 55.9 67.3 50.2 133.1 65.2 11.3 102.8 104.5 60.9 161.6 16.5 18.8 31.8 97.4 41.5 14.4 2.6 102.7 23.9 13.1 71.2 32.7 19.6 70.2 26.2 155.9 23.6 87.5 2.7 33.7 11.1 10.4 38.4 69.6 151.5 125.2 35.4 15.1 67.9 23.7 40.2 73.3 69.9 41.0 78.9 54.3 87.8 15.9 0.2 24.2 81.4 25.4 95.0 17.8 35.1 26.0 15.5 60.7 0.5 33.9 53.6 167.7 0.3 0.6 74.9 52.1 65.0 61.5 63.1 59.2 0.1 78.9 0.7 33.0 42.6 0.3 0.5 13.6 96.5 79.6 0.4 27.5 2.4 27.9 1.9 0.4 2.6 51.2 112.3 112.4 20.6 50.3 11.0 91.6 163.9 98.2 80.0 98.6 0.2 0.8 0.3 65.3 0.7 135.6 0.4 7.3 0.0 0.1 1.9 0.1 0.0 0.1 0.1 2.4 0.3 0.0 0.2 0.2 0.4 0.1 0.3 0.0 3.4 55.7 107.5 89.9 73.3 55.9 67.3 102.8 104.5 97.4 70.2 87.5 151.5 62.4 6.4 19.5 2.3 1.8 46.9 87.2 51.4 21.1 0.1 59.2 31.8 3.5 134.4 41.1 12.9 0.0 98.2 2.0 41.6 1.9 245.6 3.7 4.3 20.0 54.7 11.5 0.0 0.1 226.0 110.3 32.1 133.0 9.0 2.5 1.7 69.7 35.6 13.2 1.7 0.2 66.6 30.5 5.9 29.3 1.7 39.4 5.3 21.4 4.7 8.9 12.8 0.0 2.0 42.7 266.2 45.8 35.3 0.6 122.4 17.5 11.4 14.7 0.3 39.5 22.8 49.5 2.0 0.6 55.9 52.0 112.2 2.2 7.0 61.1 161.3 CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 2517.1" "Group enriched" "Detected in many" 7 "Cholangiocytes: 613.4;Hepatocytes: 2420.8" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 16 "classical monocyte: 109.6;myeloid DC: 114.5" "Group enriched" "Detected in many" 22 "dendritic cells: 114.5;monocytes: 109.6" "Group enriched" "Detected in some" 5 "Hep G2: 700.9;THP-1: 688.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No NA 40000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavorable (9.92e-4)" 94.9 14.1 0.9 3.2 1.2 27.0 43.6 0.8 1.8 26.6 3.7 82.3 24.0 60.4 7.5 41.1 54.6 272.9 66.1 1.0 1.4 6.7 2517.1 167.8 1.8 2.3 1.2 20.3 8.8 0.7 3.7 8.5 1.5 39.2 12.3 2.9 41.4 36.4 5.2 14.0 27.4 40.4 1.0 41.0 56.1 7.8 1.1 2.5 9.9 9.4 1.0 57.7 17.7 1.1 0.7 4.4 0.0 0.0 90.8 0.6 3.1 0.3 0.0 0.0 0.0 43.5 0.0 0.0 19.4 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.9 700.9 0.0 1.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 40.8 0.1 0.6 0.0 0.0 1.5 6.7 0.0 0.5 0.0 0.1 3.2 0.1 1.1 0.9 0.0 688.0 0.1 0.0 0.4 0.2 0.5 2.2 0.1 1.0 0.0 151.7 0.0 0.0 109.6 0.5 4.5 6.1 1.5 1.1 0.7 5.0 114.5 1.2 0.7 1.1 0.6 0.3 1.6 6.8 0.4 58.0 0.9 1.2 0.8 1.8 1.0 1.4 2.3 1.2 1.5 1.0 1.1 1.1 2.0 16.0 67.6 0.0 11.3 16.7 5.3 6.8 1.2 0.0 1.2 8.1 0.8 613.4 31.5 16.5 0.0 0.5 12.2 0.1 0.0 15.4 79.6 1.0 10.6 8.9 37.5 177.7 0.0 18.7 2.2 57.4 1.1 0.2 6.3 0.0 66.0 2420.8 18.1 0.0 0.0 12.2 4.1 107.3 26.7 197.8 18.6 58.7 39.2 1.0 39.6 10.4 7.2 0.0 0.0 0.9 1.3 98.9 1.8 1.5 0.6 0.9 169.0 0.9 0.0 9.8 9.8 1.0 2.3 20.6 11.6 0.8 16.9 0.9 0.7 2.6 CFP PFC ENSG00000126759 "Complement factor properdin" P27918 X 47623172-47630305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 83.9;lymphoid tissue: 58.4" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 108.1;Kupffer cells: 356.7;Langerhans cells: 164.1;Macrophages: 177.3;monocytes: 473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 8 "classical monocyte: 1167.5;intermediate monocyte: 1273.6;myeloid DC: 994.5;neutrophil: 730.3;non-classical monocyte: 868.9" "Group enriched" "Detected in all" 46 "dendritic cells: 994.5;granulocytes: 730.3;monocytes: 1273.6" "Cell line enhanced" "Detected in some" "EFO-21: 20.7;HEL: 5.0;HMC-1: 5.5;NB-4: 10.7;U-937: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072644 Approved Vesicles "Secreted to blood" NA NA 6200000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 38: EFO-21 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA072644: " "unprognostic (2.77e-3)" "unprognostic (2.21e-3)" "unprognostic (1.00e-1)" "unprognostic (2.15e-2)" "unprognostic (4.15e-2)" "unprognostic (9.66e-5)" "unprognostic (9.90e-3)" "unprognostic (1.30e-2)" "unprognostic (5.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (2.70e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.62e-2)" "unprognostic (2.17e-1)" 6.0 1.9 0.3 20.5 0.3 83.9 2.1 0.3 0.6 0.6 0.2 2.1 1.2 0.9 0.2 1.6 3.4 2.1 2.6 0.4 0.1 0.8 12.0 9.3 11.7 0.1 0.0 0.7 0.8 0.1 0.8 0.9 0.0 0.7 0.9 0.2 1.0 0.2 1.0 1.5 3.7 5.2 0.0 58.4 1.5 0.6 0.0 5.1 0.9 0.7 4.4 4.9 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 20.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 5.0 0.2 0.0 0.1 1.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.0 10.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.2 1.0 0.0 0.1 0.5 0.1 0.4 0.4 0.1 0.1 7.2 0.0 131.5 1167.5 39.9 3.0 1273.6 2.3 6.7 15.1 1.8 994.5 2.6 21.8 8.1 730.3 12.3 868.9 30.9 14.1 1071.9 0.3 0.3 0.3 0.6 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 9.1 1.0 5.8 4.0 0.1 0.3 1.2 3.4 0.7 0.4 0.9 1.5 2.8 0.0 0.0 0.3 1.7 0.3 0.0 0.2 0.2 0.4 0.4 7.4 0.0 2.5 1.4 0.7 0.5 2.0 1.1 0.6 1.3 4.0 108.1 2.0 17.3 1.7 1.1 0.0 0.0 356.7 164.1 0.3 0.9 177.3 5.4 0.0 473.7 0.3 4.1 2.0 0.3 0.3 0.1 1.2 1.2 0.3 0.1 0.5 7.5 1.9 0.0 1.5 1.2 0.0 0.2 0.5 3.0 0.4 4.8 3.1 0.6 0.0 CKM CKMM ENSG00000104879 "Creatine kinase, M-type" P06732 19 45306413-45322875 "Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "skeletal muscle: 73556.4;tongue: 26058.9" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 5353.0" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 64.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 68.8" "Region enriched" "Detected in single" 15 "olfactory bulb: 1.5" "Low region specificity" "Detected in many" HPA047859 Enhanced NA NA 170000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA047859: AB_2680186" "unprognostic (3.51e-1)" "unprognostic (7.63e-2)" "unprognostic (2.61e-2)" "unprognostic (4.14e-1)" "unprognostic (7.68e-3)" "unprognostic (4.04e-3)" "unprognostic (1.85e-2)" "unprognostic (4.23e-2)" "unprognostic (5.19e-2)" "unprognostic (1.81e-1)" "unprognostic (5.00e-1)" "unprognostic (9.46e-3)" "unprognostic (9.67e-8)" "unprognostic (3.23e-1)" "unprognostic (1.73e-1)" "unprognostic (2.33e-1)" "unprognostic (1.95e-1)" 8.5 2.7 0.1 0.0 0.3 0.7 12.4 0.2 0.3 0.9 0.0 6.6 0.1 1.8 0.0 512.5 0.4 0.2 4618.8 0.0 0.0 2.1 5.2 8.7 0.4 0.1 0.0 2.8 5.3 0.0 2.1 0.3 0.2 134.8 0.1 0.2 340.9 2.1 73556.4 23.4 4.3 2.4 0.0 2.5 23.5 9.9 0.0 2.5 8.5 26058.9 0.4 1.5 3.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.0 5.8 0.0 0.3 16.3 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.0 0.0 0.0 0.0 6.3 0.2 0.2 0.0 0.0 68.8 0.0 0.0 0.1 0.1 0.0 0.1 16.3 0.1 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.2 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 5353.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 11.7 0.1 15.3 0.8 0.9 51.2 0.0 0.0 0.4 0.0 0.7 141.8 0.0 0.1 1.3 0.4 0.4 0.0 6.6 0.0 0.5 0.0 0.0 0.9 0.3 53.2 1.5 3.2 0.0 0.0 0.9 0.0 0.0 0.5 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.8 0.0 0.0 639.9 47.3 16.5 1.6 0.0 0.1 0.3 2.6 3.6 0.0 0.1 CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.4;stomach 1: 15.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 418.8;Paneth cells: 449.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 7.7;Daudi: 6.4;RT4: 6.7;SK-BR-3: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" 6.2 1.1 0.3 2.3 0.4 0.1 5.7 0.2 0.3 2.4 2.3 16.4 4.1 1.0 1.9 3.3 1.4 1.2 0.7 0.3 0.3 4.5 10.4 4.7 0.3 0.5 0.4 1.6 4.0 2.1 0.9 1.5 0.4 1.3 6.8 0.1 6.8 1.3 0.5 13.5 10.1 0.3 0.4 1.8 15.6 0.5 0.5 0.1 4.9 0.3 0.3 5.0 2.7 0.6 0.1 2.6 0.0 0.1 0.7 0.1 7.7 1.9 1.5 2.0 3.1 1.5 4.2 6.4 0.0 0.1 0.7 2.5 0.0 0.0 0.2 1.3 0.0 0.0 0.7 0.1 3.5 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.3 0.0 0.2 1.9 0.3 1.3 0.0 0.0 0.0 0.9 6.7 0.3 0.9 2.6 6.8 0.1 0.7 0.9 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.9 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.4 0.2 0.3 0.3 0.3 0.5 0.4 0.4 0.4 0.5 0.6 13.0 9.6 3.1 0.3 1.1 0.1 6.6 4.2 2.2 0.1 6.8 3.4 0.7 30.0 6.9 1.8 0.0 19.1 2.8 418.8 7.9 26.9 0.0 6.0 2.5 3.4 7.7 0.0 0.0 10.7 14.9 3.3 59.7 6.7 4.5 0.8 8.2 10.6 16.8 0.0 0.0 49.9 26.4 2.4 1.4 0.0 0.3 4.6 3.6 1.9 1.4 1.1 0.0 0.0 0.0 28.1 449.9 0.4 0.1 3.3 99.1 4.7 10.3 1.1 6.6 1.5 3.2 0.0 0.0 3.9 0.6 9.4 1.3 0.3 55.2 12.2 CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725718 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 132.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 363.0;HMC-1: 637.3;NB-4: 901.1;THP-1: 694.7;U-937: 358.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "HPA042690: AB_10795511" "unprognostic (9.33e-2)" "unprognostic (6.66e-2)" "unprognostic (2.40e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.33e-1)" "unprognostic (8.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.29e-2)" "unprognostic (5.26e-2)" "unprognostic (4.99e-2)" "unprognostic (2.79e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (6.09e-2)" "unprognostic (8.66e-3)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" 17.5 17.5 5.0 7.0 5.6 132.6 14.1 7.9 9.1 44.4 2.9 12.0 4.8 31.9 1.6 8.4 37.5 6.2 16.3 4.4 7.2 21.1 12.1 15.0 2.7 10.2 7.9 31.5 7.5 2.4 22.3 5.5 8.1 22.5 1.9 0.7 6.9 4.8 4.4 16.8 9.7 8.1 7.2 14.0 8.0 9.1 6.2 2.6 12.8 1.0 0.8 19.2 28.2 6.0 2.6 3.5 0.0 2.9 33.7 45.3 79.2 139.3 37.9 15.6 15.7 0.1 0.0 0.4 1.7 70.2 0.8 1.6 0.4 0.2 10.7 0.6 22.9 363.0 0.1 0.0 21.3 0.2 637.3 33.7 0.2 1.9 2.3 0.1 17.9 16.1 4.1 2.2 29.0 2.6 3.1 901.1 1.6 0.3 4.6 30.7 0.2 0.2 0.8 0.4 0.0 3.8 4.2 0.0 58.1 0.0 0.9 694.7 100.3 1.1 41.6 0.7 0.7 2.1 2.2 0.5 47.3 358.7 44.2 1.4 24.3 0.4 0.9 11.5 0.1 0.6 0.3 0.2 17.7 0.4 2.0 4.5 1.6 5.7 5.6 4.8 0.2 8.2 5.0 5.6 7.9 9.1 4.4 7.2 10.2 7.9 8.1 7.2 6.2 6.0 12.4 3.2 5.4 10.4 3.9 32.0 32.2 2.9 27.3 20.5 30.8 31.9 3.4 8.6 4.0 29.5 10.4 8.6 5.0 1.7 119.3 11.0 6.5 17.0 70.7 16.9 26.5 36.4 9.0 3.1 72.4 107.2 4.1 14.1 5.7 18.9 51.4 6.3 49.4 21.9 8.3 4.5 10.2 21.5 73.3 19.9 70.8 29.6 78.2 9.4 11.2 70.4 14.4 8.0 12.9 3.1 1.7 67.4 0.9 21.4 0.5 13.7 5.0 20.7 65.7 20.2 59.2 17.2 21.7 26.3 45.9 18.3 5.8 56.7 3.5 17.8 CLEC4A "CD367, CLECSF6, DCIR, DDB27" ENSG00000111729 "C-type lectin domain family 4 member A" Q9UMR7 12 8123617-8138607 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 21.6;lymphoid tissue: 26.9" "Group enriched" "Detected in many" 4 "Kupffer cells: 79.9;Langerhans cells: 119.3;Macrophages: 88.5;monocytes: 98.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 226.8;classical monocyte: 331.7;intermediate monocyte: 198.1;myeloid DC: 327.4;neutrophil: 298.3;non-classical monocyte: 130.0" "Group enriched" "Detected in all" 13 "dendritic cells: 327.4;granulocytes: 298.3;monocytes: 331.7" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA007842 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA007842: AB_1078534" "unprognostic (9.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.41e-2)" "unprognostic (3.13e-2)" "unprognostic (2.69e-1)" "unprognostic (9.34e-2)" "unprognostic (5.49e-2)" "unprognostic (8.22e-2)" "unprognostic (1.62e-1)" "unprognostic (7.84e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.42e-3)" "unprognostic (1.42e-1)" "unprognostic (1.35e-2)" "unprognostic (3.05e-1)" "unprognostic (9.79e-2)" 4.1 2.4 3.0 26.9 3.0 21.6 4.6 3.1 5.9 3.2 2.9 4.6 5.1 3.9 4.3 2.6 2.6 7.4 1.9 3.0 3.0 1.7 4.2 11.1 9.4 4.0 3.1 4.3 1.8 1.0 2.0 4.9 3.1 2.3 6.0 3.5 2.8 3.0 1.6 5.4 4.7 4.6 3.1 15.4 2.4 2.4 2.6 6.2 1.7 2.6 8.9 7.7 1.8 3.3 0.2 0.0 0.3 0.9 1.7 4.2 0.5 1.2 0.5 0.9 1.3 1.6 0.7 0.7 0.1 0.6 0.3 0.2 0.9 0.2 0.6 1.2 1.2 0.7 0.7 0.4 2.1 2.3 2.9 2.1 0.9 0.4 1.2 2.7 0.2 1.6 0.4 0.6 1.2 0.6 0.6 1.7 0.6 0.6 0.4 0.4 0.7 1.1 0.6 1.1 0.2 0.4 0.2 0.8 0.0 1.4 0.1 0.1 0.2 1.6 1.0 0.6 0.8 0.7 0.1 0.9 0.2 0.8 0.0 226.8 331.7 1.1 0.5 198.1 0.6 14.1 0.9 1.3 327.4 25.0 0.6 0.6 298.3 3.3 130.0 44.4 0.6 168.9 3.0 3.0 3.1 5.9 3.0 3.0 4.0 3.1 3.1 3.1 2.6 3.3 1.1 0.0 4.6 3.9 8.6 4.2 0.8 0.6 0.0 0.6 0.7 2.0 0.8 0.0 2.0 0.0 4.2 0.3 8.9 0.4 1.9 0.1 5.5 0.2 0.6 1.5 1.8 2.7 2.2 0.5 0.2 1.4 0.5 0.3 2.5 1.5 0.7 1.3 23.8 0.0 2.4 0.3 0.0 79.9 119.3 1.5 2.5 88.5 7.2 3.7 98.8 1.0 6.2 4.5 2.9 0.6 1.2 1.5 0.7 0.8 0.0 0.3 2.3 1.1 0.0 1.1 1.1 0.6 0.4 0.3 3.3 0.3 2.1 0.7 0.2 0.9 CLEC4D "CD368, CLECSF8, Dectin-3, MCL, Mpcl" ENSG00000166527 "C-type lectin domain family 4 member D" Q8WXI8 12 8509475-8522366 "CD markers, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 64.7" "Group enriched" "Detected in some" 5 "Kupffer cells: 10.6;Macrophages: 11.9;monocytes: 15.1" "Cancer enriched" "Detected in single" 50 "testis cancer: 11.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "classical monocyte: 57.1;neutrophil: 98.7" "Group enriched" "Detected in many" 32 "granulocytes: 98.7;monocytes: 57.1" "Group enriched" "Detected in some" 5 "NB-4: 2.4;NTERA-2: 9.0;SuSa: 9.1;U-937: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA004906 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA004906: AB_1078535" "unprognostic (1.10e-1)" "unprognostic (4.94e-2)" "unprognostic (4.78e-2)" "unprognostic (1.27e-1)" "unprognostic (4.39e-1)" "unprognostic (3.84e-2)" "unprognostic (7.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.70e-1)" "unprognostic (3.81e-1)" "unprognostic (7.91e-5)" "unprognostic (1.12e-2)" "unprognostic (8.57e-2)" "unprognostic (7.89e-2)" "unprognostic (2.18e-1)" 2.3 0.2 0.0 7.3 0.1 64.7 0.2 0.0 0.2 3.1 0.3 0.1 0.1 0.1 0.5 0.4 0.7 0.4 0.3 0.0 0.0 0.2 0.5 3.1 0.6 0.1 0.1 0.0 0.5 0.0 0.0 0.7 0.1 0.1 0.1 0.6 0.4 0.0 0.1 0.0 0.2 0.8 0.0 7.0 0.2 0.2 0.4 0.3 0.1 0.7 0.3 2.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 9.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.9 57.1 0.0 0.0 4.5 0.0 0.3 0.0 0.1 2.4 0.0 0.0 0.1 98.7 0.0 1.2 0.7 0.0 12.4 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.6 0.8 0.0 0.0 11.9 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 CLEC4G "LSECtin, UNQ431" ENSG00000182566 "C-type lectin domain family 4 member G" Q6UXB4 19 7728958-7733906 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 14.9;liver: 53.3;lymphoid tissue: 15.1" "Cell type enriched" "Detected in some" 15 "Hepatic stellate cells: 730.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 18.8;myeloid DC: 15.1" "Group enriched" "Detected in many" 4 "dendritic cells: 15.1;monocytes: 18.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003789, HPA014044" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB003789: , HPA014044: AB_1846916" "unprognostic (7.20e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.64e-1)" "unprognostic (4.47e-2)" "unprognostic (1.35e-1)" "unprognostic (7.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.23e-1)" "unprognostic (3.29e-2)" "unprognostic (7.45e-2)" "unprognostic (3.04e-1)" "unprognostic (2.13e-8)" "unprognostic (5.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (6.65e-2)" 14.9 0.5 1.9 2.4 1.9 1.2 2.6 4.0 2.9 0.1 2.0 1.4 0.4 0.1 0.3 0.4 4.8 1.6 1.2 2.5 1.9 0.5 53.3 1.0 15.1 2.3 2.1 0.5 0.3 0.0 0.1 1.0 2.1 0.3 0.9 0.0 1.1 0.3 0.4 1.1 2.0 1.0 2.1 3.4 0.9 0.4 4.3 0.2 0.5 0.0 0.3 7.7 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.8 0.0 0.0 4.2 0.0 0.3 0.0 0.0 15.1 4.2 0.1 0.0 0.4 0.5 0.5 0.7 0.0 4.5 1.9 1.9 4.0 2.9 2.5 1.9 2.3 2.1 2.1 2.1 4.3 2.1 0.1 0.0 0.0 0.3 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 18.7 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 730.3 7.1 0.8 0.0 1.1 0.0 0.0 46.7 2.9 0.0 0.3 2.6 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.7 0.0 0.3 0.3 1.1 0.8 0.0 0.1 CLEC5A "CLECSF5, MDL-1" ENSG00000258227 "C-type lectin domain containing 5A" Q9NY25 7 141927357-141947007 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 41.3" "Group enriched" "Detected in some" 6 "Hofbauer cells: 18.0;Langerhans cells: 67.5;Macrophages: 58.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "classical monocyte: 9.1" "Lineage enriched" "Detected in many" 8 "monocytes: 9.1" "Group enriched" "Detected in some" 23 "HL-60: 40.9;U-937: 157.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA054137 Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA054137: AB_2732582" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.69e-2)" "unprognostic (4.56e-2)" "unprognostic (1.33e-5)" "unprognostic (4.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.58e-3)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.23e-2)" "unprognostic (1.64e-1)" 1.1 1.8 1.1 7.3 1.2 41.3 0.6 1.3 2.6 0.7 2.1 0.2 0.1 0.3 0.0 1.2 0.5 1.8 0.5 1.0 3.3 0.5 1.8 4.0 0.1 2.2 3.3 0.3 1.3 1.2 0.5 0.9 2.2 0.4 0.3 1.0 1.2 0.5 0.0 2.6 0.0 1.3 1.6 1.1 0.2 0.5 4.9 0.6 0.7 0.0 0.1 2.3 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.3 0.0 0.0 9.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 1.8 1.1 1.2 1.3 2.6 1.0 3.3 2.2 3.3 2.2 1.6 4.9 2.4 0.1 0.0 4.8 0.7 0.6 1.9 0.0 0.0 0.0 0.2 0.1 0.1 0.3 1.5 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.5 0.0 0.0 0.1 0.0 0.2 0.8 0.0 0.0 2.5 0.0 0.0 0.0 18.0 0.0 0.2 0.0 0.0 4.7 67.5 0.7 0.0 58.1 1.8 7.5 6.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.9 0.4 0.0 0.0 0.2 0.0 0.1 0.0 1.4 0.3 0.4 0.0 0.0 0.0 CLEC6A "CLECSF10, dectin-2" ENSG00000205846 "C-type lectin domain containing 6A" Q6EIG7 12 8455962-8478330 "Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 1.0;lymphoid tissue: 1.1" "Cell type enhanced" "Detected in single" "monocytes: 1.5" "Cancer enriched" "Detected in single" 6 "testis cancer: 1.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 5.4;myeloid DC: 2.2" "Group enriched" "Detected in many" 12 "dendritic cells: 2.2;monocytes: 5.4" "Cell line enriched" "Detected in single" 4 "NTERA-2: 3.4" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.44e-1)" "unprognostic (9.07e-3)" "unprognostic (5.32e-3)" "unprognostic (1.27e-2)" "unprognostic (2.54e-1)" "unprognostic (4.27e-4)" "unprognostic (6.06e-2)" "unprognostic (2.17e-1)" "unprognostic (1.11e-1)" "unprognostic (4.64e-2)" "unprognostic (7.30e-4)" "unprognostic (8.89e-2)" "unprognostic (3.29e-1)" "unprognostic (2.43e-1)" "unprognostic (2.60e-2)" 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CLPB "ANKCLB, FLJ13152, HSP78, SKD3" ENSG00000162129 "Caseinolytic mitochondrial matrix peptidase chaperone subunit B" Q9H078 11 72285495-72434680 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cataract, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 144.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 5136.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.5" "Group enriched" "Detected in all" 5 "dendritic cells: 25.5;granulocytes: 7.7;monocytes: 15.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039005, HPA039006, HPA064571" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 83: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA039005: AB_2676305, HPA039006: AB_10672767, HPA064571: AB_2685290" "unprognostic (9.36e-2)" "unprognostic (1.06e-2)" "unprognostic (2.51e-1)" "unprognostic (1.23e-1)" "unprognostic (2.99e-1)" "unprognostic (2.05e-2)" "unprognostic (8.22e-2)" "unprognostic (8.37e-2)" "unprognostic (2.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.01e-2)" "unprognostic (1.18e-1)" "prognostic favorable (8.36e-8)" "unprognostic (9.29e-2)" "unprognostic (1.25e-1)" "unprognostic (5.83e-2)" "unprognostic (3.28e-2)" 6.0 7.2 3.2 6.6 4.2 11.7 3.5 6.3 7.7 2.9 0.4 3.7 3.9 3.4 2.0 4.0 3.2 3.0 6.2 3.9 6.2 9.0 11.2 3.5 3.7 7.6 5.0 2.9 5.9 9.3 2.2 6.1 8.6 2.3 3.4 6.7 5.9 3.8 8.8 2.4 2.6 6.4 5.0 3.9 3.8 144.6 6.6 4.0 5.7 7.2 3.3 3.8 2.6 5.2 12.7 39.4 9.5 20.5 12.2 9.8 28.8 12.9 8.9 21.8 15.5 55.5 19.1 28.6 30.5 13.0 35.0 26.5 30.6 31.0 23.0 26.3 24.0 23.5 38.3 28.4 10.1 28.0 45.3 14.6 7.7 37.7 33.2 6.4 23.3 26.9 39.7 20.3 12.7 33.0 26.7 23.3 10.5 40.4 35.4 22.2 16.6 14.3 9.9 22.6 27.7 16.9 16.8 39.9 30.8 11.5 22.4 22.0 16.9 29.0 18.0 27.4 25.9 9.9 16.6 18.4 14.6 22.2 19.5 7.7 15.7 0.8 3.0 13.5 3.1 1.9 1.6 2.8 25.5 1.8 2.1 1.8 1.1 2.6 7.8 4.3 1.1 7.8 3.2 4.2 6.3 7.7 3.9 6.2 7.6 5.0 8.6 5.0 6.6 5.2 9.0 16.0 9.7 4.6 6.1 0.4 5.3 5.9 2.2 4.1 7.7 5.0 3.7 2.8 8.6 9.2 4.2 13.0 3.2 3.9 5.9 13.7 1135.5 7.2 13.4 8.0 0.0 11.4 9.8 16.3 17.1 5.5 7.1 9.7 3.8 9.2 1.4 10.7 21.6 3.3 9.8 1.8 10.2 5.9 4.2 5136.8 25.1 13.2 1.8 14.0 8.8 1.9 2.1 11.1 10.4 10.4 1.4 18.4 14.2 6.3 4.3 24.3 5.3 5.5 13.1 3.5 8.1 40.9 22.9 6.0 1.1 33.1 3.6 16.7 2.6 6.6 COMMD9 "FLJ31106, HSPC166" ENSG00000110442 "COMM domain containing 9" Q9P000 11 36269284-36289449 "Predicted intracellular proteins" "Ion transport, Sodium transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009142 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA009142: AB_1847105" "unprognostic (1.56e-2)" "unprognostic (4.75e-3)" "unprognostic (7.57e-2)" "unprognostic (4.40e-3)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-3)" "unprognostic (2.62e-1)" "unprognostic (6.15e-2)" "prognostic favorable (8.54e-4)" "unprognostic (4.94e-2)" "unprognostic (2.40e-1)" "unprognostic (6.08e-3)" "unprognostic (7.24e-2)" "unprognostic (1.71e-1)" "unprognostic (7.31e-3)" "unprognostic (1.88e-1)" 26.8 32.1 33.8 21.8 34.1 50.8 24.3 35.1 36.7 17.2 29.6 19.6 21.1 14.1 25.1 24.9 20.3 20.5 31.1 33.8 33.8 38.7 36.6 26.8 26.0 34.2 34.4 19.4 26.4 27.4 23.2 24.8 33.9 14.0 24.2 20.3 21.9 13.3 64.2 27.1 20.2 21.9 36.9 26.8 19.7 14.9 36.0 30.6 25.1 61.7 32.0 20.6 16.6 39.1 28.8 33.4 36.1 38.2 54.5 37.8 20.0 33.6 42.6 74.7 69.8 27.3 23.9 33.0 32.5 67.1 57.5 41.4 64.0 45.2 69.6 39.9 75.2 18.2 57.6 48.0 51.0 71.6 52.3 48.0 49.5 40.9 25.0 38.5 62.2 43.3 45.7 34.7 59.4 36.9 47.9 49.6 38.5 55.6 70.3 52.1 81.7 38.9 78.6 26.6 44.1 49.2 47.9 47.1 43.6 29.2 102.7 27.0 41.9 45.0 34.4 107.9 49.8 24.3 53.2 37.2 51.8 66.4 44.0 85.6 376.6 173.7 91.4 359.0 86.8 130.7 87.5 88.4 383.6 138.3 99.8 83.4 42.7 94.8 300.9 145.8 114.5 315.2 33.8 34.1 35.1 36.7 33.8 33.8 34.2 34.4 33.9 36.9 36.0 39.1 26.9 22.4 29.4 2.6 27.0 15.3 12.7 37.4 13.1 16.6 25.6 38.7 29.9 12.8 20.2 18.4 10.4 43.2 28.3 16.9 78.2 70.1 9.5 13.2 20.3 22.8 25.7 23.1 9.4 46.4 52.9 21.2 11.7 17.0 19.0 25.6 15.4 17.1 105.1 5.0 8.7 20.4 34.6 59.5 35.6 28.9 17.7 57.5 24.9 1.9 61.3 36.3 33.0 4.5 8.8 46.5 17.7 11.7 10.4 4.9 30.3 62.5 8.5 22.9 13.1 12.3 22.8 32.8 33.3 19.6 21.6 24.9 19.2 28.4 24.6 12.0 COMT ENSG00000093010 Catechol-O-methyltransferase P21964 22 19941371-19969975 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine metabolism, Neurotransmitter degradation" "Methyltransferase, Transferase" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 885.9;Syncytiotrophoblasts: 648.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 818.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001169, CAB011233" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" NA NA 43000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Endoplasmic reticulum" "CAB011233: , HPA001169: AB_1078402" "unprognostic (5.20e-2)" "unprognostic (2.73e-2)" "unprognostic (3.08e-2)" "prognostic favorable (3.68e-4)" "unprognostic (2.99e-2)" "unprognostic (2.32e-3)" "unprognostic (5.54e-3)" "unprognostic (9.14e-2)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (2.14e-3)" "prognostic favorable (5.67e-4)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.27e-1)" "unprognostic (7.09e-2)" "unprognostic (3.97e-1)" "unprognostic (1.07e-2)" 78.1 180.7 99.3 39.6 108.9 71.8 85.5 114.4 140.4 105.3 119.6 80.1 55.0 76.9 47.7 198.0 65.2 60.3 81.7 96.6 107.4 94.2 292.3 93.3 49.7 117.4 107.9 107.4 74.0 61.5 48.7 116.9 117.3 87.2 20.7 17.2 133.7 70.5 98.6 119.7 64.1 38.3 109.2 63.6 99.8 51.7 102.7 26.9 59.1 49.9 26.0 86.9 124.1 124.3 131.3 131.7 15.0 128.3 141.2 122.5 6.0 143.9 178.8 120.3 133.6 112.1 148.6 51.7 62.7 208.9 48.6 172.9 23.6 152.0 26.2 115.1 163.4 92.5 65.1 267.1 265.1 155.0 35.3 159.2 180.7 104.3 101.3 116.6 113.2 82.0 383.2 109.4 100.6 818.5 63.4 267.9 32.4 361.1 42.9 88.2 127.9 72.8 129.0 404.5 60.4 53.8 47.7 405.7 125.7 7.6 84.0 436.6 137.5 212.7 82.2 71.0 109.6 37.5 18.0 41.2 236.0 211.3 152.5 62.2 312.2 59.6 77.9 218.1 64.0 56.8 52.6 62.6 251.5 57.8 45.5 51.7 12.0 73.5 151.5 291.4 72.6 178.6 99.3 108.9 114.4 140.4 96.6 107.4 117.4 107.9 117.3 109.2 102.7 124.3 99.1 125.0 88.1 22.9 33.1 102.1 231.9 248.1 188.4 73.4 174.9 218.4 41.9 104.4 162.7 152.6 10.4 885.9 80.1 53.0 320.8 201.0 4.6 59.1 72.2 86.7 84.5 70.0 16.8 193.0 113.5 103.1 46.4 46.9 71.7 95.7 77.1 262.0 311.4 25.2 17.2 97.7 191.2 177.0 107.7 13.3 134.2 137.0 240.1 20.6 137.0 158.7 41.2 25.1 45.7 170.2 108.8 179.8 45.5 132.4 179.9 73.8 135.8 43.2 138.1 143.3 113.1 8.4 5.7 236.4 123.5 648.5 41.8 222.0 122.3 206.6 CORO1C "coronin-3, HCRNN4" ENSG00000110880 "Coronin 1C" Q9ULV4 12 108645109-108731526 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041737 Approved NA NA 13000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA041737: AB_10804115" "unprognostic (2.86e-1)" "unprognostic (2.82e-2)" "unprognostic (2.83e-1)" "unprognostic (3.96e-1)" "unprognostic (6.50e-3)" "unprognostic (1.32e-2)" "prognostic unfavorable (5.59e-5)" "unprognostic (2.49e-2)" "unprognostic (9.84e-2)" "unprognostic (2.41e-1)" "unprognostic (1.07e-2)" "unprognostic (3.96e-1)" "unprognostic (1.67e-3)" "unprognostic (2.93e-2)" "unprognostic (8.33e-2)" "unprognostic (3.39e-3)" "unprognostic (4.90e-3)" 68.5 30.6 36.1 49.7 36.1 52.5 36.6 28.1 36.8 49.9 22.1 116.6 28.9 96.1 24.1 67.7 55.9 54.4 33.7 41.3 39.1 25.8 49.1 76.4 31.6 43.9 37.1 30.4 13.0 36.4 22.0 48.2 39.0 35.8 53.3 10.5 24.6 67.3 30.0 52.1 42.9 142.9 38.3 26.1 45.0 22.5 40.8 47.4 14.2 23.6 33.6 71.5 44.7 53.4 188.2 207.2 274.3 140.8 137.3 186.5 117.3 347.8 372.0 443.2 353.6 245.8 81.5 10.6 88.8 547.9 173.2 85.4 153.3 255.1 558.1 82.8 71.4 313.8 95.3 192.7 123.8 76.6 154.1 173.7 120.3 501.0 376.9 262.3 234.1 51.8 157.0 101.0 473.6 68.4 34.7 90.5 70.5 68.7 197.9 53.3 158.6 121.9 176.0 122.5 75.0 66.3 115.6 16.0 156.6 173.0 83.0 58.0 263.7 316.1 165.1 297.7 296.8 99.4 245.7 232.8 246.3 64.0 215.5 42.3 70.7 32.0 7.4 78.1 3.5 24.6 2.9 4.5 75.7 19.1 1.0 3.3 81.9 12.6 75.2 75.9 7.5 44.7 36.1 36.1 28.1 36.8 41.3 39.1 43.9 37.1 39.0 38.3 40.8 53.4 24.5 54.5 20.7 18.3 27.8 138.0 168.2 47.7 66.0 7.1 18.2 14.1 19.0 18.6 34.6 12.9 2.1 28.4 39.1 41.3 3.9 59.7 58.9 33.6 47.2 51.9 30.9 25.5 32.8 22.7 125.3 38.4 20.4 39.1 41.8 43.3 17.2 49.8 122.2 15.2 39.7 23.4 16.2 71.0 181.4 56.4 22.4 108.8 90.7 37.5 81.7 6.7 8.2 46.3 42.6 76.9 29.8 58.6 31.6 92.8 19.0 30.1 10.5 5.3 13.1 42.8 53.2 26.8 22.9 60.6 167.8 46.8 12.0 9.9 30.7 93.2 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 156.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.0;Alveolar cells type 2: 362.2;Kupffer cells: 368.5;Sertoli cells: 762.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.0;intermediate monocyte: 14.5;myeloid DC: 16.6;non-classical monocyte: 7.4" "Group enriched" "Detected in many" 5 "dendritic cells: 16.6;monocytes: 21.0" "Group enriched" "Detected in many" 4 "ASC diff: 71.1;ASC TERT1: 50.0;HSkMC: 91.2;SiHa: 68.9;THP-1: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 156.1 11.5 6.4 14.4 13.3 3.5 40.2 10.1 10.5 14.4 3.8 33.5 4.4 23.9 0.9 10.1 16.2 16.1 4.6 7.6 10.2 41.3 26.5 59.3 16.1 19.3 11.5 18.0 13.0 12.0 1.0 70.1 11.9 14.7 26.6 6.7 4.1 2.8 5.8 21.7 5.9 6.4 7.5 19.4 15.3 5.4 28.0 4.3 7.5 9.7 10.5 9.3 5.7 23.5 0.1 4.0 0.1 0.0 71.1 50.0 0.7 9.8 1.1 1.7 2.3 3.2 4.1 0.5 9.6 1.4 4.1 0.0 1.4 2.7 4.1 0.1 2.7 0.0 15.1 0.3 0.4 1.2 1.9 91.2 0.6 1.0 2.0 8.6 0.0 0.3 0.0 0.1 7.3 1.7 0.0 0.7 1.7 0.0 5.2 3.1 0.6 0.0 7.2 5.9 0.4 0.2 68.9 10.7 7.9 5.5 1.2 26.5 0.2 1.2 7.5 0.5 0.2 0.4 0.5 13.1 4.3 13.1 5.9 0.6 21.0 0.1 0.2 14.5 0.0 1.8 1.5 0.1 16.6 3.5 0.9 0.2 1.6 0.5 7.4 1.1 1.9 7.3 6.4 13.3 10.1 10.5 7.6 10.2 19.3 11.5 11.9 7.5 28.0 23.5 83.3 359.0 362.2 34.6 4.9 12.4 3.5 6.1 0.6 3.3 7.8 8.9 2.6 135.8 70.1 51.5 0.0 32.3 1.1 97.5 29.4 57.9 16.6 100.9 8.3 29.0 10.8 3.6 1.2 212.5 59.9 14.1 4.6 237.1 112.5 6.7 73.9 36.6 134.6 0.0 1.3 28.7 0.0 368.5 36.3 17.5 105.0 202.2 10.6 19.7 23.3 68.9 1.0 23.1 161.8 68.0 65.9 79.0 2.4 38.7 1.9 63.7 16.4 5.7 762.6 7.2 126.9 0.6 3.9 2.4 9.9 172.4 14.5 46.3 32.7 2.8 CPNE8 ENSG00000139117 "Copine 8" Q86YQ8 12 38646822-38907430 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 115.5;Microglial cells: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 66.8;THP-1: 38.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038600 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038600: AB_10674690" "unprognostic (1.57e-1)" "unprognostic (3.07e-1)" "unprognostic (3.38e-1)" "unprognostic (3.78e-3)" "unprognostic (8.93e-3)" "unprognostic (6.28e-3)" "unprognostic (6.74e-2)" "unprognostic (8.44e-2)" "unprognostic (5.40e-3)" "unprognostic (4.29e-1)" "unprognostic (1.28e-2)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (3.21e-1)" "unprognostic (5.13e-2)" "unprognostic (8.73e-3)" 12.0 8.3 7.0 5.4 7.6 4.6 9.6 3.1 11.5 7.8 9.2 8.1 3.3 5.1 3.5 5.4 5.0 9.0 12.2 10.1 8.9 11.2 15.5 10.1 5.4 5.0 6.5 5.7 3.2 2.5 3.3 12.0 4.6 3.7 10.2 6.0 3.2 8.9 2.9 6.1 4.6 9.1 8.8 10.6 3.7 5.8 8.0 3.1 7.8 5.3 3.2 10.1 5.3 5.5 3.1 18.7 1.3 18.5 17.0 14.3 8.6 1.6 0.1 0.0 0.0 9.4 18.2 0.0 26.3 12.7 6.8 1.0 10.8 5.6 0.0 0.0 11.3 9.9 26.3 2.2 11.3 0.0 7.8 6.7 14.2 4.2 14.9 12.9 14.3 0.0 6.0 0.0 0.0 0.0 0.0 0.1 13.8 11.5 19.0 0.0 0.0 4.3 66.8 0.5 0.0 0.5 26.0 4.7 14.1 18.8 2.3 38.8 13.6 0.0 12.7 21.6 0.1 6.5 19.3 0.2 17.2 17.8 11.0 2.7 12.0 0.0 1.6 9.4 0.3 0.2 2.1 1.8 7.7 0.6 0.9 1.5 0.7 4.5 6.3 2.5 2.1 2.5 7.0 7.6 3.1 11.5 10.1 8.9 5.0 6.5 4.6 8.8 8.0 5.5 68.8 12.8 8.2 66.3 1.6 31.1 5.9 40.8 19.9 2.1 0.6 6.5 20.3 15.7 23.3 12.9 0.0 29.2 6.9 35.8 15.6 7.6 68.9 2.7 9.4 55.9 11.5 7.4 115.5 4.9 27.2 27.1 0.0 3.0 3.8 18.5 36.0 16.5 25.7 0.0 36.3 9.1 6.1 34.1 42.4 14.5 9.6 19.4 46.2 77.8 19.8 36.4 2.1 25.6 2.9 3.6 51.3 8.2 3.3 7.4 0.0 20.9 17.0 2.7 0.0 24.5 16.9 2.7 2.1 6.1 11.2 7.8 4.3 8.6 8.9 3.5 CPVL ENSG00000106066 "Carboxypeptidase vitellogenic like" Q9H3G5 7 28995235-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 219.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 306.1;Kupffer cells: 290.3;Langerhans cells: 531.0;Macrophages: 266.2;monocytes: 176.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 61.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1136.9;intermediate monocyte: 953.5;myeloid DC: 1319.5" "Group enriched" "Detected in all" 52 "dendritic cells: 1319.5;monocytes: 1136.9" "Cell line enhanced" "Detected in many" "BEWO: 190.8;RPTEC TERT1: 801.1;U-266/84: 205.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 760000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: AB_2679429, HPA056466: AB_2683140" "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavorable (4.99e-4)" 44.0 23.5 7.5 66.3 8.7 59.8 24.9 48.9 12.0 28.5 39.6 28.9 32.8 17.1 34.6 25.4 19.8 42.1 79.3 6.8 9.9 96.7 52.9 57.6 92.9 15.2 11.4 18.1 7.9 5.4 10.1 84.9 15.4 17.9 25.7 0.9 5.3 21.3 12.5 19.3 46.5 34.1 11.8 219.0 15.5 34.4 8.8 66.7 128.4 8.3 35.8 50.6 15.8 23.4 1.5 0.2 20.3 0.1 0.1 0.0 190.8 0.0 0.0 1.9 0.4 59.8 0.1 0.0 90.3 0.8 94.4 3.2 51.8 4.2 0.6 0.4 47.9 67.0 1.2 144.5 0.0 0.0 0.3 0.3 5.9 0.7 1.6 0.0 0.6 27.5 45.5 0.1 1.6 0.0 63.4 0.4 31.6 0.1 16.0 0.3 0.0 0.6 801.1 22.8 11.9 9.4 53.6 125.5 101.7 97.0 15.1 49.6 0.0 0.4 0.8 0.5 12.0 17.5 205.5 1.0 0.2 25.0 20.8 19.5 1136.9 5.7 2.6 953.5 3.4 1.8 1.3 1.9 1319.5 1.2 1.2 1.2 23.4 5.8 327.8 34.8 1.5 1142.7 7.5 8.7 48.9 12.0 6.8 9.9 15.2 11.4 15.4 11.8 8.8 23.4 12.3 6.4 16.0 3.3 7.2 12.5 1.3 0.7 5.7 0.0 2.6 3.4 69.1 10.0 2.5 71.7 0.0 138.0 2.1 0.2 35.2 0.5 24.7 3.7 0.3 21.1 1.8 34.1 3.7 15.6 118.3 29.4 1.1 0.6 5.1 2.3 6.8 1.1 306.1 0.0 1.7 1.2 0.0 290.3 531.0 7.6 9.3 266.2 10.6 45.9 176.8 0.2 2.1 2.0 1.3 0.8 0.4 3.0 2.9 0.5 0.4 30.6 1.5 0.4 0.0 31.0 3.0 27.1 92.8 27.2 8.8 118.5 3.3 3.6 1.2 0.9 CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 545.7;Kupffer cells: 559.7;monocytes: 322.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.4;classical monocyte: 128.4;eosinophil: 75.7;intermediate monocyte: 75.7;myeloid DC: 89.9;neutrophil: 43.7;non-classical monocyte: 72.3" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.7;monocytes: 128.4" "Cell line enhanced" "Detected in all" "RPMI-8226: 1237.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved Vesicles,Microtubules "Secreted to blood" NA NA 520000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Microtubules Vesicles "HPA056390: AB_2683113" "unprognostic (3.25e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-3)" "unprognostic (4.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (2.07e-3)" "unprognostic (8.54e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-3)" "unprognostic (2.99e-1)" "unprognostic (4.63e-2)" "unprognostic (3.78e-3)" "unprognostic (3.16e-1)" 130.5 127.7 37.5 79.0 41.1 125.9 109.7 39.0 45.9 76.8 47.8 77.1 60.3 61.8 109.7 91.7 70.9 128.2 82.2 36.5 40.4 132.1 295.2 99.1 98.9 46.0 39.1 84.2 70.7 75.4 64.8 110.8 44.4 62.9 82.7 80.0 104.5 74.6 71.4 109.8 63.0 77.9 45.7 136.9 61.4 50.1 49.3 35.5 125.8 78.2 63.5 116.3 63.3 61.2 93.5 41.5 21.1 43.5 325.8 89.8 53.0 39.2 17.8 30.7 39.8 67.8 104.4 101.7 112.2 43.6 57.2 143.3 24.3 84.9 20.9 140.3 82.3 41.5 31.1 37.9 111.5 93.6 295.2 94.5 250.5 35.6 38.7 42.7 10.3 35.9 218.5 405.0 42.6 39.2 19.6 95.9 22.8 214.0 63.9 32.5 58.8 1237.2 54.7 64.9 14.0 25.7 98.1 132.8 112.8 70.1 175.5 252.7 19.1 8.0 39.6 126.2 25.9 79.4 168.4 67.7 131.6 96.0 16.3 55.4 128.4 75.7 5.1 75.7 8.0 4.3 7.5 6.5 89.9 2.1 16.6 8.8 43.7 11.0 72.3 6.2 3.9 57.6 37.5 41.1 39.0 45.9 36.5 40.4 46.0 39.1 44.4 45.7 49.3 61.2 44.7 35.3 90.1 5.9 15.3 44.1 49.1 23.1 56.9 17.9 61.7 63.8 55.7 65.8 32.2 55.2 89.6 91.5 18.3 15.6 23.5 36.0 27.6 33.9 19.3 34.2 29.3 124.8 24.7 39.7 41.7 78.4 21.9 64.1 29.9 62.0 48.2 90.3 545.7 15.2 22.1 44.5 14.2 559.7 57.6 27.4 43.5 213.8 24.9 26.2 322.8 30.5 6.2 10.1 14.6 21.0 31.5 28.6 27.8 34.0 46.3 60.6 18.5 31.5 13.1 43.2 40.8 65.5 42.0 86.3 51.1 126.7 17.3 38.9 50.4 44.0 CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.6" "Group enriched" "Detected in all" 5 "dendritic cells: 306.9;monocytes: 377.6" "Cell line enhanced" "Detected in all" "ASC diff: 795.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: AB_10960991, HPA044150: AB_10959594" "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.85e-3)" "unprognostic (7.36e-2)" "unprognostic (4.73e-3)" "unprognostic (4.28e-2)" "unprognostic (1.87e-1)" "unprognostic (9.97e-2)" "unprognostic (4.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (9.93e-2)" "unprognostic (1.28e-3)" 157.2 106.5 65.2 38.7 69.2 43.2 123.9 51.9 54.8 211.2 52.9 145.1 35.0 170.1 57.1 58.7 138.3 80.5 83.9 49.6 64.9 67.9 44.6 92.3 37.3 65.2 62.4 131.4 36.0 45.7 22.8 69.9 63.9 90.7 51.6 19.3 54.0 106.5 54.4 84.1 65.6 115.0 67.5 48.2 78.9 25.0 65.3 23.7 77.2 68.9 38.1 142.7 135.8 69.5 64.1 123.3 37.8 119.2 795.0 516.6 219.0 136.1 294.0 160.6 151.9 42.1 35.1 44.4 147.6 259.3 129.9 80.2 68.0 103.9 115.5 110.1 106.0 69.2 87.6 43.7 237.4 45.4 54.8 415.3 208.5 145.0 183.2 311.7 172.0 27.0 60.3 82.1 164.6 54.7 16.5 46.3 45.5 67.5 165.7 59.4 111.0 86.1 127.8 42.0 7.9 61.0 92.0 79.8 201.1 87.3 85.9 109.3 113.0 209.1 89.1 115.4 145.9 59.0 214.3 6.7 164.3 89.7 117.1 13.4 377.6 28.5 35.8 147.7 52.5 39.9 51.4 40.2 306.9 39.2 29.2 27.8 30.5 42.1 46.0 82.5 74.0 200.5 65.2 69.2 51.9 54.8 49.6 64.9 65.2 62.4 63.9 67.5 65.3 69.5 74.0 9.6 42.8 15.3 29.0 60.4 41.1 39.5 150.8 17.9 32.7 43.7 34.7 25.8 22.0 38.6 8.4 49.0 37.1 14.8 11.7 25.0 1.2 17.4 135.7 72.7 6.0 46.0 10.0 32.0 81.6 142.3 29.0 31.2 48.1 58.4 122.4 53.2 107.0 35.3 14.5 26.0 10.2 181.1 91.1 6.3 142.9 108.6 80.0 10.3 134.1 15.9 22.6 17.1 11.6 18.4 16.3 144.8 58.1 24.5 24.4 52.7 6.8 10.1 111.7 78.4 120.9 1.6 15.9 95.1 46.7 28.0 26.5 89.9 36.1 30.0 CSNK1A1 "CK1, CK1a, CK1alpha, CKIa, CKIalpha" ENSG00000113712 "Casein kinase 1 alpha 1" P48729 5 149492982-149551471 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 847.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016680, HPA051334" Uncertain Approved Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB016680: AB_1614518, HPA051334: AB_2681446" "unprognostic (4.27e-3)" "unprognostic (5.85e-3)" "prognostic favorable (1.15e-4)" "unprognostic (7.39e-2)" "unprognostic (2.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.27e-2)" "unprognostic (5.56e-2)" "unprognostic (4.38e-1)" "unprognostic (8.31e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (5.47e-2)" "unprognostic (1.56e-1)" "unprognostic (7.92e-2)" "unprognostic (4.41e-2)" "unprognostic (6.28e-3)" "unprognostic (6.92e-2)" 77.0 67.6 49.0 67.3 53.9 210.8 97.8 60.0 52.7 67.9 61.5 83.2 56.6 73.7 60.2 142.4 56.6 79.7 87.6 48.6 55.9 50.3 68.2 69.6 60.0 61.3 56.4 53.2 55.0 99.4 48.8 71.7 56.6 88.3 68.2 57.6 71.3 69.2 104.1 121.4 63.1 82.9 57.9 60.7 73.5 45.6 57.8 81.0 76.9 59.5 81.8 94.8 82.3 66.3 154.4 106.4 151.0 144.1 143.6 191.4 185.0 189.7 176.8 146.0 153.5 194.1 187.0 71.6 221.3 183.3 140.7 153.9 101.2 292.5 184.1 124.6 78.0 96.9 96.6 87.8 143.1 163.9 148.4 158.5 313.4 148.1 269.0 163.9 184.7 137.2 102.2 116.0 140.7 104.4 152.2 66.6 71.4 167.6 247.3 129.0 96.1 98.9 112.3 248.3 123.5 110.5 151.1 193.3 200.8 135.6 194.1 134.4 164.6 168.6 83.6 118.2 197.1 117.0 149.2 100.6 169.2 95.6 216.9 106.0 72.6 66.6 47.5 68.9 51.6 50.2 58.1 49.7 80.0 39.9 61.4 55.2 61.1 63.7 67.8 47.4 76.7 94.7 49.0 53.9 60.0 52.7 48.6 55.9 61.3 56.4 56.6 57.9 57.8 66.3 169.7 147.4 176.7 137.1 101.8 684.5 583.1 270.0 187.8 135.8 257.0 158.4 63.5 90.1 298.1 115.8 64.6 171.2 135.6 126.8 92.0 167.1 95.7 195.8 193.5 191.1 129.9 146.7 108.4 184.1 223.7 159.8 124.4 285.2 117.6 114.0 216.4 108.9 136.1 151.4 115.4 141.9 154.6 167.8 311.5 87.5 104.1 183.8 152.9 119.0 156.6 156.9 108.1 168.4 198.1 197.2 113.9 111.7 105.4 368.6 120.4 102.8 276.7 109.6 157.8 190.2 216.1 181.9 88.9 272.4 847.7 350.9 133.5 177.0 115.7 485.2 CSTA "STF1, STFA" ENSG00000121552 "Cystatin A" P01040 3 122325248-122341969 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5912.9;vagina: 1853.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2493.8;Club cells: 768.0;Kupffer cells: 579.4;monocytes: 1298.6;Squamous epithelial cells: 3020.6" "Cancer enhanced" "Detected in all" "cervical cancer: 227.7;head and neck cancer: 405.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "classical monocyte: 514.7;intermediate monocyte: 269.1;myeloid DC: 382.9;neutrophil: 245.6;non-classical monocyte: 161.7" "Group enriched" "Detected in all" 193 "dendritic cells: 382.9;granulocytes: 245.6;monocytes: 514.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 282.0;hTCEpi: 1218.6;THP-1: 789.0;U-698: 504.5;U-937: 250.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000469, HPA001031, CAB047315" Enhanced Approved Nucleoplasm,Cytosol No No 28000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "CAB000469: , CAB047315: , HPA001031: AB_1078610" "unprognostic (5.22e-3)" "unprognostic (6.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.07e-2)" "unprognostic (7.79e-3)" "prognostic favorable (5.86e-4)" "unprognostic (4.46e-1)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (7.99e-2)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (8.89e-2)" "unprognostic (3.43e-2)" "unprognostic (9.24e-3)" "unprognostic (1.99e-1)" 30.7 4.7 0.8 27.1 0.9 297.8 56.3 1.0 3.7 961.0 1.4 3.8 1.1 2.2 10.3 5912.9 4.6 7.2 5.9 0.8 1.0 2.4 38.9 26.0 25.1 1.5 0.9 21.1 3.7 0.8 5.0 19.0 1.3 19.7 3.6 0.3 996.1 9.6 4.6 369.1 5.8 6.3 1.1 20.4 30.3 1.3 1.4 46.5 2.7 2.8 941.0 39.1 1853.3 1.6 14.6 1.3 0.2 3.2 31.5 58.0 2.9 0.6 0.8 0.0 0.0 0.0 0.0 3.2 7.6 5.9 0.5 86.9 0.0 282.0 0.0 0.3 0.2 0.7 0.0 6.8 6.8 117.6 1.9 30.5 1218.6 2.9 119.1 0.0 0.0 1.5 0.8 29.9 0.5 0.8 0.2 108.3 0.0 0.5 0.0 0.0 0.9 0.0 0.0 141.3 0.0 0.0 14.1 7.5 10.4 0.1 1.6 789.0 0.5 1.7 19.7 0.2 0.9 0.0 1.7 504.5 26.4 250.3 0.3 8.8 514.7 16.4 0.6 269.1 1.5 1.5 0.7 0.6 382.9 0.5 0.5 0.7 245.6 1.9 161.7 6.9 1.0 283.2 0.8 0.9 1.0 3.7 0.8 1.0 1.5 0.9 1.3 1.1 1.4 1.6 1.1 6.4 19.8 0.0 5.0 83.5 136.5 2493.8 117.8 0.0 7.1 119.8 0.2 2.8 768.0 0.0 0.0 230.6 7.4 3.9 0.0 2.1 0.4 0.3 0.4 3.0 0.0 3.8 0.1 22.1 17.8 13.6 12.8 0.3 13.9 0.1 6.1 96.0 134.5 0.0 0.1 0.5 179.0 579.4 90.6 2.4 10.2 243.7 8.8 0.0 1298.6 0.0 20.6 0.5 0.2 46.2 1.5 3.8 2.8 30.2 0.0 0.7 115.7 0.0 32.9 8.8 24.3 0.1 0.5 3020.6 205.0 334.2 4.9 26.1 2.0 134.1 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1475.9;Hofbauer cells: 3763.5;Macrophages: 1512.6;Proximal enterocytes: 1699.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 2596.6;hTERT-RPE1: 2780.1;SK-BR-3: 2488.5" "CAB000109, HPA003001" Supported "Secreted to blood" NA NA 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" 318.6 734.6 147.0 204.9 181.9 499.0 244.0 186.0 156.5 270.8 672.7 298.0 387.6 170.7 82.8 319.4 171.6 438.4 444.1 187.8 223.6 691.6 464.8 539.6 241.0 247.6 206.6 130.7 284.8 137.3 131.5 180.7 228.6 138.2 153.4 48.3 422.1 231.7 590.3 340.9 398.3 105.0 188.9 442.0 287.2 88.9 334.4 78.1 182.1 178.2 123.1 296.4 307.5 367.1 204.6 578.9 51.4 246.2 586.5 206.3 112.1 149.4 362.2 161.8 182.8 147.5 2596.6 49.2 376.8 285.8 1265.6 1072.2 63.7 142.6 35.8 206.7 222.9 70.4 92.5 196.5 736.2 171.4 787.7 350.9 621.6 82.5 136.9 2780.1 128.2 62.1 89.2 267.6 263.3 832.6 47.0 110.9 153.1 719.7 247.9 62.5 72.5 191.2 586.6 610.8 84.2 94.8 173.3 2488.5 535.0 68.6 1022.8 232.6 170.3 556.8 92.9 79.0 216.7 432.0 382.3 26.8 867.7 468.6 509.6 211.2 578.7 170.1 156.5 309.9 90.6 28.8 72.1 110.3 144.5 18.8 82.5 107.4 319.5 192.3 265.2 120.3 89.2 489.1 147.0 181.9 186.0 156.5 187.8 223.6 247.6 206.6 228.6 188.9 334.4 367.1 139.3 112.2 228.6 48.3 62.8 72.0 223.5 473.2 71.7 168.6 108.9 113.8 251.9 314.5 459.5 548.1 110.5 211.7 156.1 1475.9 109.5 911.4 3.3 118.1 67.4 128.3 159.6 132.6 18.3 370.1 165.0 157.0 237.5 203.4 474.3 119.4 695.7 678.9 3763.5 264.2 25.2 418.2 498.5 1187.8 67.5 14.6 108.4 1512.6 227.7 20.6 382.6 179.0 256.4 27.2 42.2 392.3 832.5 128.2 122.5 111.7 1699.4 311.8 270.3 102.1 111.7 70.7 135.2 26.6 63.5 141.2 82.1 471.3 155.0 96.0 399.1 357.8 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 349.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1569.9;Proximal tubular cells: 523.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 208.5;intermediate monocyte: 137.7;memory B-cell: 83.3;myeloid DC: 183.6;naive B-cell: 56.0;non-classical monocyte: 94.8" "Group enriched" "Detected in all" 5 "B-cells: 83.3;dendritic cells: 183.6;monocytes: 208.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 306.4;HaCaT: 228.2;HDLM-2: 183.0;OE19: 197.4;RT4: 362.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" NA NA 8700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 34.3 36.4 29.4 100.6 30.2 36.9 48.8 29.9 47.1 112.8 31.4 32.5 77.8 46.7 26.8 37.9 57.6 104.6 51.3 29.6 32.9 238.2 89.5 349.6 191.8 30.8 31.4 30.0 75.5 77.6 10.1 25.7 31.5 59.7 27.3 4.7 63.0 70.7 16.3 48.4 56.7 43.1 30.7 51.8 93.9 10.1 32.7 51.8 27.7 37.7 131.3 202.2 30.6 32.4 122.0 10.0 1.2 30.5 5.4 0.5 20.3 8.6 3.0 13.9 7.0 17.6 306.4 34.6 12.6 0.0 13.5 228.2 5.2 52.6 10.1 183.0 0.4 3.0 1.3 38.4 12.1 0.4 7.1 5.6 10.7 0.2 0.0 59.4 1.0 5.9 76.0 0.0 17.9 2.8 32.6 87.8 8.9 197.4 4.9 0.3 0.4 5.9 49.9 362.1 2.6 5.2 41.5 27.8 75.4 10.1 12.5 48.0 16.4 0.2 6.2 0.0 5.3 0.8 92.4 19.5 0.1 89.2 12.3 0.0 208.5 2.0 7.6 137.7 29.7 83.3 20.5 7.4 183.6 56.0 1.8 3.8 8.7 3.2 94.8 22.9 18.3 147.5 29.4 30.2 29.9 47.1 29.6 32.9 30.8 31.4 31.5 30.7 32.7 32.4 169.8 237.2 1569.9 59.1 127.4 24.2 280.7 363.9 30.1 1.3 45.5 41.7 26.2 358.9 258.7 367.8 4.2 19.8 8.1 9.1 84.1 225.0 25.3 67.0 86.0 124.5 9.1 3.0 2.2 142.0 39.6 53.8 106.0 42.8 32.8 2.7 14.3 115.5 256.7 0.0 2.9 18.6 101.7 177.8 259.6 22.6 73.0 350.4 80.0 15.9 360.9 22.6 5.2 1.5 1.1 84.6 16.0 6.0 155.8 112.0 153.0 523.2 261.6 6.6 19.7 4.5 22.3 12.3 56.4 41.6 18.6 23.4 29.4 17.8 40.1 340.4 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730079-150765957 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 137.0;lymphoid tissue: 164.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 698.6;Kupffer cells: 2230.8;Macrophages: 1316.2;monocytes: 2312.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 2483.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 81.6;HMC-1: 187.5;U-698: 387.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" NA NA 23000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" 40.0 16.7 4.0 87.8 4.5 137.0 20.3 4.8 7.1 9.4 8.0 83.6 60.2 7.8 5.7 16.5 17.8 29.1 10.6 3.4 5.5 9.3 40.4 88.4 71.7 11.8 8.0 4.9 11.3 2.3 4.7 23.6 11.2 9.1 59.4 3.4 23.9 7.3 4.1 7.1 64.6 16.3 7.7 164.8 42.6 3.8 10.4 20.1 11.5 9.0 38.5 42.9 10.0 16.1 3.7 10.9 0.2 0.3 1.2 1.4 0.7 0.4 8.6 0.9 1.3 1.2 81.6 44.3 5.7 1.2 15.3 2.1 0.2 0.7 0.5 26.9 0.2 29.0 1.1 0.8 0.2 33.6 187.5 2.6 0.1 6.6 1.5 0.5 6.3 0.6 3.4 45.0 2.4 0.3 0.4 22.5 0.2 0.1 0.3 14.9 4.6 49.8 10.7 8.7 0.3 0.4 1.1 2.3 0.8 0.3 0.4 49.8 9.1 6.2 1.3 0.8 1.2 27.8 2.2 387.3 28.5 35.2 2.3 20.9 2483.4 218.0 41.3 1735.3 51.1 139.5 46.6 50.9 571.0 138.8 45.0 40.8 1022.2 41.8 1655.1 106.8 77.4 2577.6 4.0 4.5 4.8 7.1 3.4 5.5 11.8 8.0 11.2 7.7 10.4 16.1 37.6 109.0 158.7 1.6 255.3 17.0 31.3 72.0 4.6 2.3 21.0 8.9 5.3 74.4 143.4 42.3 12.5 3.7 198.0 549.2 0.0 183.6 6.6 126.9 8.6 44.1 42.4 22.5 10.3 177.0 5.7 34.4 71.9 39.0 106.8 9.5 60.3 30.6 698.6 0.0 9.5 205.7 73.2 2230.8 316.4 3.0 5.3 1316.2 56.9 27.2 2312.9 0.5 137.0 0.5 0.9 200.9 466.5 2.2 121.4 20.6 210.8 4.7 488.9 4.9 19.7 5.6 13.3 0.2 0.5 12.4 15.5 6.2 108.9 66.0 237.8 113.3 CYFIP1 "KIAA0068, P140SRA-1, SHYC" ENSG00000273749 "Cytoplasmic FMR1 interacting protein 1" Q7L576 15 22867052-22981063 "Predicted intracellular proteins" "Cell shape, Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 253.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 23.5;intermediate monocyte: 24.9;myeloid DC: 22.0;non-classical monocyte: 12.5" "Group enriched" "Detected in many" 5 "dendritic cells: 22.0;monocytes: 24.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068106 Approved NA NA 1100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA068106: AB_2685955" "unprognostic (1.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.85e-1)" "unprognostic (8.20e-3)" "unprognostic (3.94e-1)" "unprognostic (2.09e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.93e-1)" "unprognostic (8.56e-2)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "prognostic favorable (4.47e-5)" "unprognostic (1.20e-1)" "unprognostic (9.36e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-3)" 41.2 26.0 16.6 19.8 16.9 4.7 36.4 15.8 20.0 33.2 16.7 37.7 31.5 33.8 23.8 46.2 24.7 24.0 21.8 15.5 17.9 25.9 26.1 40.5 19.2 20.7 19.5 28.9 41.7 37.3 13.3 39.5 23.1 29.3 28.1 4.4 39.3 24.6 21.2 39.7 29.3 24.9 23.5 26.5 33.8 15.9 21.7 10.2 27.5 14.4 16.2 29.9 36.6 28.6 67.6 74.8 35.5 72.2 42.7 49.3 49.7 47.5 35.7 32.1 31.7 70.0 32.9 0.2 34.1 50.0 32.9 64.2 31.9 58.8 29.7 36.2 45.5 41.3 40.9 51.9 37.3 14.4 29.5 39.3 43.1 25.4 29.7 33.6 48.3 37.0 20.0 23.4 37.8 58.1 1.5 25.7 25.1 87.1 61.8 18.3 45.7 16.6 81.4 114.3 43.1 44.3 40.9 67.2 46.3 35.0 53.1 30.3 49.5 58.7 47.2 24.3 69.6 3.4 7.7 0.7 56.6 32.5 33.7 0.0 23.5 0.4 0.5 24.9 2.4 2.0 2.1 1.0 22.0 0.3 0.4 0.1 0.7 4.3 12.5 3.3 1.6 8.2 16.6 16.9 15.8 20.0 15.5 17.9 20.7 19.5 23.1 23.5 21.7 28.6 56.7 35.3 37.9 18.6 5.7 20.0 27.3 33.8 23.9 2.3 28.9 29.8 7.4 17.2 37.9 18.4 2.1 38.6 4.1 78.7 11.7 33.5 4.5 33.8 35.8 50.7 17.4 9.2 41.8 35.0 40.0 32.2 42.8 50.6 8.8 99.1 35.3 31.5 108.7 5.0 46.1 34.0 28.5 104.5 29.5 5.3 36.4 73.8 28.4 253.9 43.3 17.9 0.0 19.6 16.0 43.2 43.2 32.4 6.3 33.2 41.9 21.8 39.6 2.0 26.3 29.5 40.8 9.0 17.9 40.4 26.3 31.7 4.8 38.5 33.0 34.8 CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease variant, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 170.8;Prostatic glandular cells: 747.6;Urothelial cells: 498.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "classical monocyte: 156.9" "Lineage enriched" "Detected in many" 24 "monocytes: 156.9" "Cell line enhanced" "Detected in many" "ASC diff: 128.7;ASC TERT1: 136.8;HSkMC: 551.3;hTERT-RPE1: 128.9;SiHa: 270.0;U-87 MG: 142.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 34.6" "CAB011705, HPA026863" Approved Uncertain Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB011705: AB_731810, HPA026863: AB_10600900" "unprognostic (7.25e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.68e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (9.69e-2)" "unprognostic (4.20e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.87e-3)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "prognostic unfavorable (2.76e-4)" 28.4 12.0 2.7 31.9 6.2 2.0 29.4 1.6 8.9 34.9 10.4 3.7 2.2 41.0 19.5 7.6 44.9 23.8 29.2 2.5 2.3 24.1 7.0 16.8 11.6 3.6 2.9 5.6 7.2 0.9 14.8 4.5 3.0 34.7 2.1 1.2 4.3 39.2 3.4 6.3 5.8 35.1 3.6 27.3 15.9 8.0 7.3 28.3 8.7 5.5 1.9 35.0 6.7 1.5 7.0 71.9 2.3 0.0 128.7 136.8 0.4 0.6 4.4 1.3 12.3 0.2 30.1 0.0 19.1 17.8 3.1 58.7 0.3 4.0 2.3 5.5 3.8 0.0 21.2 0.0 36.0 0.2 0.1 551.3 55.3 30.7 1.4 128.9 0.0 0.3 0.7 0.2 0.7 29.2 0.3 22.5 7.5 10.4 14.2 0.1 0.0 0.2 13.4 0.9 0.5 2.1 270.0 38.8 0.0 7.5 49.4 10.8 0.0 1.1 0.2 107.9 0.1 0.3 0.2 0.0 142.2 0.1 11.8 1.6 156.9 0.0 0.1 23.2 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.1 6.5 0.1 18.6 0.7 0.1 70.2 2.7 6.2 1.6 8.9 2.5 2.3 3.6 2.9 3.0 3.6 7.3 1.5 56.8 19.2 66.3 0.0 1.7 17.7 118.4 86.9 8.0 0.7 18.3 42.0 3.4 0.0 79.7 46.0 0.0 0.3 1.1 0.9 15.6 6.0 15.1 11.7 100.4 103.8 1.8 0.0 4.5 0.5 0.8 114.1 3.6 28.2 3.8 0.1 7.5 12.2 12.6 0.0 0.3 1.3 4.1 103.0 50.6 12.1 159.7 112.2 17.8 64.6 140.1 1.6 3.1 0.0 0.2 0.6 0.1 170.8 0.3 747.6 0.1 1.6 11.2 0.5 19.7 4.5 32.7 12.6 2.6 2.4 14.2 0.3 2.4 1.3 1.0 498.7 CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 594.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 404.3;Hofbauer cells: 148.9;Proximal enterocytes: 206.3" "Group enriched" "Detected in all" 4 "liver cancer: 176.9;melanoma: 85.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 151.5;neutrophil: 126.3" "Group enriched" "Detected in many" 21 "granulocytes: 126.3;monocytes: 151.5" "Cell line enhanced" "Detected in many" "Hep G2: 299.6;HSkMC: 54.7;RPTEC TERT1: 78.5;SK-MEL-30: 103.6;WM-115: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059155 Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Mitochondria Cytosol "HPA059155: AB_2683933" "prognostic favorable (1.05e-4)" "unprognostic (4.21e-2)" "unprognostic (2.34e-1)" "unprognostic (1.83e-3)" "unprognostic (3.71e-3)" "unprognostic (1.31e-2)" "prognostic favorable (8.62e-6)" "unprognostic (6.04e-2)" "unprognostic (1.73e-1)" "unprognostic (4.04e-1)" "unprognostic (1.25e-3)" "unprognostic (8.76e-3)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (7.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" 23.1 50.3 45.2 15.7 59.0 1.3 21.8 57.0 59.3 27.6 75.6 27.6 77.8 19.8 11.6 11.9 34.0 19.1 30.7 42.2 49.3 46.4 594.4 71.7 24.6 63.0 56.1 32.6 8.3 18.5 29.6 6.2 62.7 41.8 20.7 22.5 40.4 29.5 37.9 17.5 81.9 13.2 50.6 13.0 13.8 12.6 58.8 23.6 12.6 49.2 28.0 24.3 23.2 69.2 0.2 0.0 2.7 0.2 4.6 3.3 0.4 1.9 11.7 3.9 7.8 13.7 0.8 0.0 4.3 7.6 0.2 0.1 0.0 0.0 1.7 1.4 1.0 0.0 0.4 299.6 16.2 0.4 0.3 54.7 0.5 0.1 0.0 12.8 5.9 0.0 0.3 0.1 8.3 0.0 0.0 0.2 2.3 0.3 0.5 0.1 2.4 0.5 78.5 0.2 0.2 0.2 0.1 0.0 103.6 2.4 1.6 2.2 5.9 0.0 0.2 0.1 6.0 0.0 0.0 0.1 0.1 0.3 42.9 0.0 151.5 0.4 0.2 17.1 0.3 0.7 0.2 0.5 6.5 0.0 0.1 0.0 126.3 0.0 1.2 0.8 0.0 44.1 45.2 59.0 57.0 59.3 42.2 49.3 63.0 56.1 62.7 50.6 58.8 69.2 10.6 3.2 28.9 33.6 0.9 5.2 52.4 8.5 21.6 15.3 12.7 18.8 5.1 17.2 11.3 3.7 27.1 0.7 0.5 37.0 9.8 12.1 1.0 12.6 4.3 10.3 24.5 8.4 2.2 12.0 0.7 35.4 2.6 14.8 2.5 1.9 19.6 404.3 148.9 10.1 3.9 20.0 4.1 18.2 5.1 1.0 47.5 104.3 49.8 15.0 92.4 28.7 0.0 26.7 108.5 9.7 44.0 26.7 0.0 43.3 206.3 76.9 21.4 14.1 0.0 12.8 7.2 0.7 0.1 3.2 3.1 1.2 2.3 1.2 30.3 20.4 DENND1A "FAM31A, FLJ21129, KIAA1608" ENSG00000119522 "DENN domain containing 1A" Q8TEH3 9 123379654-123930152 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 258.9;Excitatory neurons: 188.2;Inhibitory neurons: 175.8;Late spermatids: 88.5;Microglial cells: 178.0;Oligodendrocyte precursor cells: 165.4;Oligodendrocytes: 145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 9 "dendritic cells: 12.1;granulocytes: 20.4;monocytes: 21.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020481 Approved Vesicles,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Vesicles, Cytosol" "HPA020481: AB_2092106" "unprognostic (1.35e-1)" "unprognostic (3.96e-2)" "unprognostic (2.00e-1)" "unprognostic (4.25e-2)" "unprognostic (1.62e-2)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (3.19e-3)" "unprognostic (2.14e-2)" "unprognostic (2.14e-2)" "unprognostic (2.48e-3)" "unprognostic (5.63e-2)" "prognostic favorable (4.11e-5)" "unprognostic (1.25e-1)" "unprognostic (1.51e-1)" "unprognostic (9.66e-2)" "unprognostic (4.31e-2)" 8.5 8.3 8.2 10.3 8.3 27.0 7.1 2.7 10.3 7.9 6.8 10.6 11.3 8.3 4.6 7.7 8.7 7.2 7.3 8.1 6.2 11.4 10.8 6.9 9.0 5.6 6.0 7.9 6.2 11.9 10.2 11.3 4.9 7.7 9.6 10.3 6.1 7.6 8.4 6.9 12.6 9.9 4.8 14.2 6.9 9.5 6.4 7.1 10.8 4.8 6.2 7.6 6.5 5.7 29.0 16.7 14.7 28.0 9.8 15.3 68.3 27.4 41.0 22.9 19.6 23.0 12.5 23.1 5.5 22.3 30.1 15.9 12.6 19.9 22.2 9.8 9.7 10.9 39.1 17.1 13.2 13.2 7.0 14.2 17.6 18.9 32.2 8.0 20.6 21.8 30.3 17.2 18.7 16.5 15.8 19.1 29.4 33.1 25.2 24.3 14.4 19.5 11.4 10.1 31.1 25.3 22.1 14.4 16.9 9.6 19.8 32.8 9.7 24.5 9.4 28.9 14.6 26.0 21.7 16.0 20.6 25.9 16.5 20.4 21.1 4.3 1.8 14.6 0.9 1.7 1.3 0.8 12.1 1.8 0.8 1.0 12.8 0.8 12.8 1.9 0.6 5.3 8.2 8.3 2.7 10.3 8.1 6.2 5.6 6.0 4.9 4.8 6.4 5.7 6.4 0.0 1.5 258.9 10.0 5.1 2.6 2.5 1.8 16.1 4.8 4.3 7.7 7.2 1.7 16.5 16.7 10.0 6.8 25.3 5.9 4.3 35.1 5.0 8.2 10.5 12.0 20.2 188.2 5.1 32.2 7.6 20.9 3.9 4.5 8.8 7.5 14.5 18.0 32.0 175.8 7.6 2.0 21.4 8.2 88.5 14.6 18.7 3.6 178.0 18.7 11.6 5.2 165.4 145.2 6.1 9.5 11.3 13.1 5.3 18.3 16.0 2.9 13.1 0.0 6.7 5.9 3.8 1.4 3.8 2.8 8.8 5.3 4.5 7.8 3.9 DHRS4 "FLJ11008, humNRDR, SCAD-SRL, SDR-SRL, SDR25C2" ENSG00000157326 "Dehydrogenase/reductase 4" Q9BTZ2 14 23953734-23969279 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 235.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA023972 Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Nuclear membrane" "HPA023972: AB_1854890" "unprognostic (1.21e-2)" "unprognostic (2.59e-1)" "unprognostic (3.46e-2)" "unprognostic (3.79e-3)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (7.35e-3)" "unprognostic (1.61e-3)" "unprognostic (2.66e-1)" "unprognostic (1.19e-2)" "unprognostic (1.06e-2)" "unprognostic (7.65e-2)" "prognostic favorable (4.55e-6)" "unprognostic (2.03e-2)" "unprognostic (1.48e-1)" "unprognostic (2.03e-1)" "unprognostic (5.68e-2)" 34.1 45.8 8.6 10.4 9.2 6.9 34.5 8.8 9.7 30.5 10.1 43.5 34.0 27.1 5.2 45.8 23.6 5.9 49.1 8.3 8.6 92.0 109.7 28.0 10.2 9.2 8.6 33.0 40.3 8.8 19.3 5.3 9.2 31.9 13.5 3.9 31.2 8.4 62.2 44.7 38.6 8.3 8.6 32.2 33.7 37.9 9.0 9.6 25.4 14.0 8.5 30.5 33.1 9.5 15.1 29.6 10.4 17.2 16.6 18.5 0.1 27.4 15.3 11.5 9.1 6.5 16.5 13.3 14.3 14.6 7.6 18.1 8.6 12.3 10.1 34.6 16.5 7.8 23.5 36.6 9.5 11.6 45.2 18.0 14.8 9.2 20.8 12.3 14.4 19.6 11.8 30.4 15.8 52.3 21.1 10.7 9.9 18.9 30.3 33.8 18.0 41.4 12.1 17.1 19.9 16.1 27.7 17.6 13.8 6.8 16.0 14.6 25.5 13.3 13.8 13.9 9.0 22.8 22.8 3.5 11.8 12.6 13.6 5.4 54.4 6.0 18.0 45.8 21.4 21.5 20.3 18.2 47.4 18.5 20.1 19.5 2.3 18.1 25.5 39.4 19.4 36.2 8.6 9.2 8.8 9.7 8.3 8.6 9.2 8.6 9.2 8.6 9.0 9.5 16.6 16.0 30.5 6.2 12.5 12.5 10.4 15.7 55.2 5.1 22.2 31.9 35.4 17.2 21.3 14.7 0.0 9.6 17.8 34.2 78.2 6.4 50.4 13.1 11.6 14.6 19.2 20.8 2.6 9.8 6.0 23.7 34.7 7.8 13.9 10.5 20.0 68.1 30.4 6.7 2.1 50.1 8.2 29.2 13.5 66.1 11.1 35.9 5.4 3.7 33.2 18.1 47.4 4.0 5.0 5.3 22.3 17.3 24.6 11.2 51.8 235.4 23.2 1.8 6.6 13.5 18.1 59.4 1.9 61.6 13.4 3.8 18.1 22.9 71.8 9.0 DHRS4L2 SDR25C3 ENSG00000187630 "Dehydrogenase/reductase 4 like 2" Q6PKH6 14 23969874-24006408 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 136.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 204.2;Proximal enterocytes: 326.4;Proximal tubular cells: 581.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA023972 Uncertain Approved "Nuclear membrane,Vesicles" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Nuclear membrane" "HPA023972: AB_1854890" "unprognostic (1.41e-2)" "unprognostic (2.83e-3)" "unprognostic (1.25e-1)" "unprognostic (2.68e-2)" "unprognostic (1.47e-1)" "unprognostic (2.53e-1)" "unprognostic (6.02e-2)" "unprognostic (3.97e-3)" "unprognostic (7.34e-2)" "prognostic favorable (3.21e-4)" "unprognostic (1.57e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-3)" "unprognostic (6.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (3.65e-2)" 27.2 39.5 28.8 14.6 29.6 11.5 30.5 28.3 38.4 26.9 30.8 34.7 34.4 19.7 12.8 38.4 18.6 10.6 45.9 28.5 27.8 122.5 136.2 22.5 14.6 29.3 28.7 25.2 34.0 24.5 16.7 10.0 28.7 32.5 26.6 6.7 24.7 20.7 50.7 37.1 42.0 18.4 28.6 29.3 27.9 41.4 29.4 16.9 21.5 28.5 16.5 26.0 26.1 29.9 18.7 29.0 4.9 24.4 46.2 47.9 0.6 17.3 34.3 24.8 18.4 8.4 22.5 12.6 11.5 35.3 16.0 20.6 22.3 29.1 20.6 43.3 13.3 3.1 24.8 52.4 34.0 15.3 47.9 50.0 36.4 16.3 23.7 17.0 29.5 40.0 10.1 44.9 26.7 61.5 40.4 16.5 9.7 45.9 31.8 64.9 19.9 38.2 35.6 23.7 26.0 15.7 24.5 21.5 15.0 10.3 25.2 24.5 20.8 12.9 13.4 15.4 8.8 25.5 21.1 3.8 11.1 23.7 18.8 4.8 56.3 6.9 19.4 47.2 20.1 21.9 20.9 22.2 45.4 17.4 21.0 19.1 2.6 17.2 29.3 37.4 21.8 33.6 28.8 29.6 28.3 38.4 28.5 27.8 29.3 28.7 28.7 28.6 29.4 29.9 39.3 16.0 29.6 10.4 17.8 27.8 46.1 56.8 27.9 9.9 45.5 54.4 17.2 47.1 34.3 25.8 2.1 21.2 22.9 37.9 127.2 40.0 20.7 20.6 20.1 32.0 37.3 24.2 7.3 55.7 7.3 36.4 13.3 16.5 17.7 31.8 50.0 204.2 146.1 11.8 6.7 61.7 42.7 55.9 42.8 35.4 43.8 41.9 51.6 10.3 65.0 79.5 35.0 10.1 8.5 30.4 54.9 37.2 10.8 32.5 326.4 581.7 28.6 8.3 32.9 24.2 32.7 17.2 1.7 42.1 40.2 13.0 21.3 37.5 78.1 42.4 DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.5" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1712.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB033241: AB_2094323, HPA045210: AB_2679256" "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" 22.2 13.2 7.2 22.6 12.8 10.3 16.7 5.7 10.4 18.8 2.4 11.9 21.9 14.9 8.4 17.1 14.3 25.7 8.9 7.4 12.9 12.6 68.5 29.6 16.6 12.4 9.4 24.0 11.8 9.2 6.2 4.5 12.1 9.9 10.1 3.3 15.0 13.4 5.8 7.1 19.4 18.2 6.9 24.7 8.4 3.7 12.9 17.0 10.3 10.1 12.0 18.2 14.2 24.4 22.2 6.2 7.8 0.2 42.4 72.5 0.1 35.2 31.9 32.1 23.6 0.0 9.2 11.7 50.6 32.9 5.1 5.2 0.0 8.3 58.7 11.6 7.3 10.0 11.1 0.2 18.8 4.5 0.6 57.5 3.0 25.7 29.3 67.7 26.8 6.8 0.4 36.4 17.0 0.0 23.6 6.4 0.9 0.2 7.5 0.1 37.1 18.6 39.4 0.1 11.1 8.8 30.1 2.5 0.3 0.8 0.0 10.2 30.9 69.2 5.0 56.4 70.6 3.0 0.1 0.2 10.2 12.6 56.2 18.2 61.1 4.1 11.6 29.5 14.8 2.2 13.3 11.0 32.7 4.9 12.5 11.1 59.8 13.3 27.1 0.9 15.8 21.9 7.2 12.8 5.7 10.4 7.4 12.9 12.4 9.4 12.1 6.9 12.9 24.4 25.5 16.0 39.1 23.8 15.4 7.6 8.8 9.4 18.8 2.5 8.4 8.3 5.3 40.0 11.5 7.3 0.0 0.2 19.2 3.3 5.9 2.5 7.0 1.5 15.2 14.7 3.0 13.3 258.6 6.4 0.2 30.0 10.7 1.7 9.5 4.5 17.2 54.2 17.1 0.0 30.5 5.5 6.1 130.4 27.0 4.0 33.5 73.7 3.6 105.9 98.1 4.8 27.8 34.2 1712.3 5.3 2.1 18.8 17.0 4.9 21.0 6.6 8.6 0.1 13.1 16.0 17.7 1.2 3.1 19.7 5.5 0.1 31.4 5.1 6.8 9.3 DPYSL2 "CRMP2, DHPRP2, DRP-2, DRP2" ENSG00000092964 "Dihydropyrimidinase like 2" Q16555 8 26514031-26658178 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 549.9" "Cell type enhanced" "Detected in all" "Adipocytes: 362.9;Oligodendrocytes: 367.2" "Cancer enhanced" "Detected in all" "glioma: 89.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 65.8;intermediate monocyte: 74.5;myeloid DC: 71.2;non-classical monocyte: 48.8;plasmacytoid DC: 42.2" "Group enriched" "Detected in all" 5 "dendritic cells: 71.2;monocytes: 74.5" "Cell line enhanced" "Detected in many" "ASC diff: 263.7;Karpas-707: 279.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002381, CAB018719" Supported Supported "Plasma membrane,Cytosol" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "CAB018719: AB_2085366, HPA002381: AB_1847244" "unprognostic (2.88e-2)" "unprognostic (1.01e-2)" "unprognostic (9.51e-2)" "unprognostic (3.16e-3)" "unprognostic (8.23e-2)" "unprognostic (1.68e-2)" "unprognostic (1.51e-1)" "unprognostic (9.95e-3)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (1.79e-2)" "unprognostic (4.13e-2)" "unprognostic (5.58e-2)" "unprognostic (9.32e-3)" "unprognostic (1.23e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (5.41e-5)" 60.0 34.8 252.6 22.5 348.0 3.5 48.0 332.4 266.7 25.3 0.0 44.8 10.4 24.9 11.4 18.3 29.6 29.4 58.6 276.1 263.2 21.3 17.6 78.2 17.4 362.4 296.0 40.8 11.0 7.1 22.1 43.7 389.9 19.7 19.0 64.0 18.5 14.9 19.2 25.8 27.6 32.9 257.9 33.6 21.5 11.2 305.0 19.3 22.5 25.8 20.1 35.6 26.9 549.9 22.0 104.1 100.2 53.9 263.7 120.6 9.8 41.9 97.0 39.2 50.6 41.0 31.0 32.7 29.7 131.7 78.8 20.9 106.6 42.0 37.1 74.2 9.2 37.0 36.9 57.9 168.5 8.0 14.5 150.8 59.5 107.1 61.9 125.5 80.0 24.9 1.1 279.1 39.9 13.9 64.3 8.1 78.8 69.9 20.0 84.3 40.3 21.8 66.2 25.0 45.6 95.8 51.0 0.5 28.6 65.7 7.8 14.8 145.0 88.2 34.8 74.3 18.5 39.1 43.3 24.8 127.7 48.1 46.0 1.3 65.8 0.6 9.1 74.5 3.3 8.5 8.1 6.2 71.2 4.4 4.0 5.2 1.7 11.3 48.8 42.2 13.3 30.3 252.6 348.0 332.4 266.7 276.1 263.2 362.4 296.0 389.9 257.9 305.0 549.9 362.9 131.4 71.7 193.9 11.5 40.4 1.0 13.2 2.2 111.4 44.4 58.4 105.0 84.4 19.4 22.0 31.3 15.1 64.8 4.5 3.9 21.4 3.1 41.6 154.3 154.6 60.7 22.3 191.9 2.0 9.1 144.9 6.1 33.6 20.8 33.0 211.3 22.8 51.1 141.3 157.0 87.0 4.1 223.5 192.3 10.6 109.0 111.1 120.9 81.5 163.5 165.2 22.6 102.1 367.2 12.6 6.2 89.5 6.5 1.1 4.7 24.4 10.5 38.6 138.1 51.8 110.6 3.8 17.0 1.6 33.8 4.5 14.8 16.8 12.1 1.2 ECHDC1 dJ351K20.2 ENSG00000093144 "Ethylmalonyl-CoA decarboxylase 1" Q9NTX5 6 127288712-127343609 "Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 230.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035445, HPA035446" Uncertain Approved Vesicles NA NA 56000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA035445: AB_10669860, HPA035446: AB_2732468" "unprognostic (9.57e-2)" "unprognostic (1.63e-2)" "unprognostic (2.46e-3)" "unprognostic (1.34e-1)" "unprognostic (4.09e-1)" "unprognostic (3.68e-2)" "unprognostic (5.03e-3)" "unprognostic (4.89e-3)" "unprognostic (4.97e-2)" "unprognostic (1.76e-1)" "unprognostic (3.99e-1)" "unprognostic (9.97e-2)" "unprognostic (8.21e-3)" "unprognostic (6.83e-2)" "unprognostic (2.86e-1)" "unprognostic (1.39e-1)" "unprognostic (1.40e-2)" 92.9 29.4 21.8 36.8 24.5 16.2 37.3 26.4 28.6 36.4 32.3 58.4 46.8 21.4 23.0 33.5 23.2 27.5 42.6 22.0 27.0 92.5 93.8 56.8 41.3 28.1 24.7 21.1 27.9 26.2 14.1 36.2 28.5 33.8 53.8 30.0 46.3 28.4 39.3 22.7 40.7 33.4 24.4 28.4 37.0 18.2 24.7 41.1 38.7 52.2 42.6 43.4 23.4 32.3 58.3 45.6 64.0 59.3 92.9 87.7 54.1 92.7 112.1 78.0 99.0 79.7 43.1 87.6 77.8 88.6 88.4 46.9 0.1 69.6 98.3 52.4 43.3 116.9 58.4 128.3 82.6 158.0 63.4 99.6 81.9 73.1 61.6 70.6 71.8 63.2 147.6 51.6 105.7 55.1 105.7 73.5 52.9 29.0 55.8 49.0 78.7 72.3 142.8 70.8 73.3 71.2 52.1 1.8 131.3 48.3 1.8 182.6 75.2 47.8 76.9 121.8 104.8 65.7 141.0 116.3 87.2 136.4 114.7 19.0 71.6 24.0 23.4 57.5 24.7 28.6 19.8 22.9 66.6 29.2 23.7 24.2 28.6 15.3 43.1 50.5 22.1 43.9 21.8 24.5 26.4 28.6 22.0 27.0 28.1 24.7 28.5 24.4 24.7 32.3 37.0 96.1 114.0 32.3 59.7 26.1 42.3 94.2 35.3 26.4 30.8 28.3 60.8 32.9 102.4 31.3 31.3 106.8 49.3 35.6 127.2 76.1 64.7 47.0 48.3 32.6 13.8 22.9 47.4 79.5 85.6 45.8 38.2 40.2 43.7 32.9 26.0 68.8 85.8 28.6 41.0 35.7 59.0 48.4 38.7 24.4 32.9 55.9 35.6 40.3 55.3 33.5 47.4 55.3 95.0 54.4 41.1 31.2 48.3 31.1 74.4 230.3 47.0 42.3 26.3 55.7 33.0 27.6 28.6 34.7 22.9 65.5 46.3 88.2 56.9 52.7 ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 113.3;Fibroblasts: 118.6;Melanocytes: 74.7;Pancreatic endocrine cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 402.1;BJ hTERT+: 293.1;fHDF/TERT166: 279.6;hTEC/SVTERT24-B: 195.6;LHCN-M2: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" 49.3 15.4 7.6 11.8 8.5 0.8 27.1 7.3 14.7 293.8 6.1 17.7 9.4 51.2 484.1 1370.5 20.1 76.5 81.3 8.1 8.3 15.9 61.2 26.3 1.2 17.4 8.9 8.9 4.1 3.5 12.7 44.6 15.4 15.5 18.1 0.9 223.9 14.0 7.0 70.0 12.4 32.6 8.9 11.5 12.4 2.7 9.4 1.3 11.1 7.8 135.0 24.4 360.1 10.7 35.4 3.5 12.6 0.2 73.9 402.1 11.4 126.9 293.1 76.2 99.5 1.9 19.1 0.6 1.3 279.6 8.8 71.5 0.2 15.0 79.3 0.6 0.7 5.7 4.1 0.7 20.4 0.3 125.5 35.7 0.9 195.6 7.2 112.8 21.3 0.7 27.7 0.8 215.2 0.1 0.4 4.2 1.4 147.8 4.1 2.0 92.7 0.5 2.8 0.1 0.8 0.4 28.8 0.9 106.4 5.8 0.3 34.0 5.8 159.3 23.9 18.3 27.9 0.5 1.1 1.5 84.6 11.7 22.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.6 8.5 7.3 14.7 8.1 8.3 17.4 8.9 15.4 8.9 9.4 10.7 9.1 0.0 1.1 2.9 0.6 14.7 1.9 6.9 0.0 0.7 0.5 0.6 1.8 7.2 7.9 3.7 0.0 2.2 0.6 1.0 0.0 6.2 0.3 3.1 113.3 15.7 0.0 0.0 12.1 4.3 40.9 118.6 7.7 2.5 10.2 1.0 42.5 1.0 17.0 1.7 10.9 1.4 18.3 2.2 22.8 0.3 9.9 10.8 74.7 2.8 0.1 0.5 0.0 1.0 4.4 70.2 1.1 22.2 0.4 1.5 0.1 0.1 0.4 1.2 13.1 4.1 32.3 0.7 0.6 28.1 19.0 10.9 2.1 5.0 0.5 6.9 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3" "Cell type enhanced" "Detected in many" "Ductal cells: 45.1;Enteroendocrine cells: 48.7;Intestinal goblet cells: 61.1;Oligodendrocytes: 76.3;Pancreatic endocrine cells: 63.7;Undifferentiated cells: 97.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 86.5;HUVEC TERT2: 74.2;TIME: 79.2;U-251 MG: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" No No 380000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.1 1.6 2.1 9.2 3.7 0.5 1.6 4.1 4.2 2.5 0.0 22.6 21.0 1.8 1.9 0.6 4.4 3.7 3.3 2.2 4.3 3.8 0.4 1.8 2.9 5.7 4.5 10.6 3.9 6.1 2.9 4.0 4.8 1.9 23.3 2.9 1.5 3.0 0.2 0.9 21.8 3.3 5.0 2.4 1.7 1.8 5.4 1.2 7.3 0.3 1.7 4.4 1.0 8.2 43.4 17.2 17.2 27.7 1.6 1.5 0.0 10.0 0.5 27.3 5.7 6.3 16.6 0.6 20.2 4.0 86.5 39.6 10.8 52.8 7.7 0.1 4.1 0.0 1.9 0.1 16.5 0.0 4.3 5.3 17.5 48.7 0.3 25.4 74.2 2.4 1.8 0.1 5.7 6.4 1.1 0.3 4.0 49.0 11.2 5.3 18.0 0.8 14.7 4.0 18.0 19.3 17.4 0.7 0.2 1.5 1.1 0.5 79.2 11.5 29.6 29.4 69.5 0.0 0.2 0.1 21.8 0.9 0.5 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 3.7 4.1 4.2 2.2 4.3 5.7 4.5 4.8 5.0 5.4 8.2 0.4 3.2 0.0 5.5 0.3 0.8 1.7 20.5 0.0 15.4 0.1 0.1 1.3 7.2 8.6 0.0 0.0 0.5 0.1 24.3 0.0 45.1 2.6 1.0 0.8 1.2 48.7 0.0 34.1 8.0 2.8 5.0 1.1 2.4 0.0 0.5 0.4 0.4 9.6 6.7 32.3 61.1 6.1 7.6 1.4 0.8 0.9 7.2 0.0 21.5 0.7 18.4 0.0 5.5 76.3 63.7 12.6 0.7 0.3 2.3 5.5 0.2 1.7 1.8 0.0 0.6 2.1 0.5 3.5 0.0 0.4 1.1 0.3 0.2 97.2 1.1 EPHX1 EPHX ENSG00000143819 "Epoxide hydrolase 1" P07099 1 225810124-225845563 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1178.6;liver: 1705.1" "Cell type enhanced" "Detected in many" "Granulosa cells: 349.9;Hepatocytes: 757.6;Theca cells: 1042.6" "Cancer enriched" "Detected in all" 6 "liver cancer: 1047.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 1161.8;SiHa: 413.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020593, HPA048847" Enhanced NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA020593: AB_10601373, HPA048847: AB_2680538" "unprognostic (2.85e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.53e-3)" "unprognostic (2.50e-1)" "unprognostic (6.60e-2)" "unprognostic (3.92e-2)" "prognostic favorable (7.02e-5)" "unprognostic (1.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.32e-4)" "unprognostic (8.10e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "unprognostic (1.88e-2)" 245.8 1178.6 233.5 23.6 252.5 22.7 163.7 239.0 249.3 188.3 345.8 82.0 102.2 108.1 97.6 159.6 153.8 96.5 94.0 221.3 233.7 110.7 1705.1 146.8 39.1 225.3 234.9 329.1 536.1 147.7 105.8 32.9 223.6 113.2 52.5 30.7 143.6 128.1 142.5 71.5 52.8 109.6 210.1 55.7 99.9 74.3 258.4 25.9 171.1 95.6 33.4 135.4 140.4 227.2 32.1 202.3 12.3 108.5 1161.8 120.2 24.3 29.7 49.2 28.1 35.1 38.8 293.6 1.3 128.7 147.3 30.6 38.1 32.7 16.8 12.1 7.8 46.5 21.8 83.5 282.7 129.8 12.9 15.1 109.2 40.0 74.6 6.3 116.5 22.1 13.4 14.5 27.3 50.4 30.3 13.5 31.0 61.6 178.1 79.4 27.8 15.2 92.9 91.1 132.5 98.3 13.0 413.0 192.1 51.3 32.1 131.7 43.5 46.8 41.9 35.4 54.5 59.0 9.1 38.9 4.1 63.5 14.2 59.5 0.0 2.6 0.1 0.2 0.7 0.4 0.1 0.3 0.2 0.6 0.2 0.5 0.3 0.2 0.7 0.3 0.9 0.3 0.8 233.5 252.5 239.0 249.3 221.3 233.7 225.3 234.9 223.6 210.1 258.4 227.2 196.9 0.0 14.0 41.1 5.7 19.6 121.8 244.2 74.0 8.8 29.7 27.4 1.2 102.9 255.5 51.5 29.2 46.6 3.4 34.5 17.6 95.3 10.2 142.9 32.2 82.7 10.8 7.0 3.1 73.0 7.6 175.6 30.5 93.4 5.7 349.9 88.2 757.6 149.1 1.7 5.0 17.5 103.7 30.9 28.7 28.4 311.3 25.8 42.7 23.4 9.6 99.2 0.0 7.1 19.4 45.5 27.2 159.1 9.5 40.4 63.4 128.9 174.3 10.1 223.5 29.3 146.9 4.4 5.1 129.0 17.6 22.8 4.7 1042.6 31.5 108.5 ESD ENSG00000139684 "Esterase D" P10768 13 46771256-46797420 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 569.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039700 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039700: AB_10697553" "unprognostic (3.05e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (7.66e-2)" "unprognostic (1.75e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.73e-2)" "unprognostic (3.31e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (2.91e-2)" "unprognostic (2.71e-2)" "unprognostic (2.18e-1)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" 123.8 87.5 83.0 73.0 85.5 95.1 146.7 86.3 110.8 141.0 87.7 125.7 106.7 129.7 160.1 93.6 121.8 96.4 151.5 84.3 98.6 194.4 277.2 92.3 93.5 87.3 85.6 179.0 67.3 109.9 81.5 81.9 89.7 112.5 135.0 122.0 92.8 140.3 149.8 83.3 93.4 166.2 94.3 63.9 83.0 54.2 82.4 155.7 155.0 179.0 110.3 104.9 96.2 100.0 138.4 77.9 229.8 160.4 264.5 441.9 62.5 190.8 280.9 264.7 204.6 131.6 162.8 156.5 56.9 233.3 194.0 137.1 256.8 227.2 333.0 180.4 270.4 200.3 70.7 208.6 220.5 400.1 82.2 304.6 207.0 167.9 229.4 316.2 253.2 260.3 200.3 40.7 433.5 135.1 352.7 260.0 59.8 175.2 148.8 277.1 133.6 106.2 378.4 55.4 115.0 130.1 85.0 72.6 160.3 157.6 137.1 223.0 169.2 94.4 113.0 187.5 181.8 27.6 63.5 135.7 205.3 223.2 131.2 35.0 129.4 55.7 48.5 113.6 80.9 104.1 97.6 76.3 142.8 83.4 114.1 90.5 15.0 109.3 106.1 170.7 90.6 100.3 83.0 85.5 86.3 110.8 84.3 98.6 87.3 85.6 89.7 94.3 82.4 100.0 139.0 54.5 56.8 37.5 77.2 134.1 227.4 300.5 148.0 51.5 114.1 123.2 99.2 167.3 111.7 154.5 41.7 160.4 51.2 59.1 360.0 168.0 135.5 102.2 120.6 112.5 108.8 99.5 22.7 103.2 141.0 162.9 51.0 80.7 96.4 71.1 132.1 154.7 227.5 21.9 19.3 114.6 175.0 140.2 148.0 34.8 267.8 108.2 165.4 25.3 144.3 199.5 36.0 23.6 36.2 85.4 92.3 211.4 35.9 99.1 137.1 569.1 94.2 77.3 151.2 196.0 484.2 61.6 46.3 120.6 129.3 74.4 78.2 151.2 199.8 143.6 FADS1 "D5D, FADS6, FADSD5, LLCDL1, TU12" ENSG00000149485 "Fatty acid desaturase 1" O60427 11 61799627-61829318 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 521.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042705 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA042705: AB_10795709" "unprognostic (8.28e-2)" "unprognostic (3.54e-1)" "unprognostic (1.29e-1)" "unprognostic (1.99e-1)" "unprognostic (8.17e-3)" "unprognostic (1.40e-1)" "unprognostic (1.99e-2)" "unprognostic (3.23e-3)" "unprognostic (7.88e-2)" "unprognostic (1.94e-2)" "unprognostic (4.10e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.95e-9)" "unprognostic (2.29e-2)" "unprognostic (3.59e-2)" "prognostic unfavorable (2.79e-4)" "prognostic unfavorable (1.33e-4)" 26.2 67.7 43.1 19.8 39.2 9.7 13.6 38.4 40.7 19.6 70.7 9.5 5.5 21.3 6.6 5.2 17.4 14.5 22.6 39.3 58.5 9.7 52.8 20.3 9.8 57.9 62.1 27.5 10.0 27.2 21.3 21.1 52.2 19.6 4.9 35.1 6.4 15.8 17.5 15.5 6.7 20.5 46.4 8.0 9.4 11.9 68.7 8.1 6.0 7.8 9.2 12.7 10.2 56.0 66.3 170.1 159.1 41.1 313.2 521.2 46.4 42.0 204.5 69.9 118.9 53.3 143.2 2.3 43.4 60.5 177.2 84.7 130.8 114.1 51.7 12.2 18.4 107.9 191.2 98.9 169.1 23.4 10.4 238.1 38.3 154.7 74.7 73.8 64.1 104.7 59.9 118.6 70.1 18.6 78.6 23.6 94.2 5.5 63.0 85.4 162.5 231.2 81.5 29.0 80.7 89.6 106.7 1.7 90.0 58.4 38.6 98.6 62.1 71.8 70.8 74.2 50.6 112.9 111.3 55.4 42.6 108.9 61.4 7.5 33.2 6.2 12.1 40.4 2.6 2.5 4.0 4.9 28.0 8.7 2.3 5.4 2.6 6.9 17.4 23.6 2.9 15.7 43.1 39.2 38.4 40.7 39.3 58.5 57.9 62.1 52.2 46.4 68.7 56.0 10.3 6.4 77.9 28.7 3.2 2.7 2.5 48.5 1.2 78.9 2.6 3.7 30.4 8.6 25.3 12.9 27.1 9.5 12.4 0.9 0.0 15.2 8.7 4.9 30.7 16.6 9.7 46.3 9.4 33.4 50.0 34.9 6.1 7.8 37.9 65.3 9.3 74.5 37.2 69.0 14.7 0.6 16.2 21.7 21.0 16.4 29.8 27.6 32.0 12.2 32.0 70.5 6.2 13.6 27.4 7.6 0.0 21.4 2.1 6.4 0.1 1.1 8.0 91.9 0.0 40.3 31.9 6.5 17.5 2.3 1.4 9.3 5.5 75.2 1.4 1.6 FAH ENSG00000103876 "Fumarylacetoacetate hydrolase" P16930 15 80152490-80186946 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 301.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 266.8;Proximal tubular cells: 305.5" "Cancer enhanced" "Detected in all" "liver cancer: 23.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 316.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041370, HPA044093" Enhanced Approved Nucleoplasm,Cytosol NA NA 220000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA041370: AB_2677438, HPA044093: AB_2678806" "unprognostic (3.15e-1)" "unprognostic (5.65e-2)" "unprognostic (1.64e-1)" "unprognostic (6.16e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.19e-2)" "unprognostic (5.83e-2)" "unprognostic (2.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "unprognostic (2.93e-1)" "unprognostic (8.98e-2)" 99.2 65.4 16.0 7.0 17.1 20.0 59.0 16.6 21.1 19.2 15.1 13.8 14.6 19.3 50.4 15.2 23.0 9.7 20.3 16.3 18.8 65.0 301.5 20.0 5.7 17.9 19.6 26.4 9.9 18.4 16.8 7.8 16.9 16.6 11.9 1.6 14.8 13.6 31.0 10.9 16.8 13.5 17.2 19.1 14.2 20.8 17.4 6.7 14.5 27.7 5.8 16.4 15.8 17.5 20.1 34.4 13.5 17.0 60.2 62.2 32.9 24.3 56.8 26.2 22.3 22.0 35.9 0.4 39.0 52.6 36.8 29.1 46.8 59.6 25.1 12.5 28.5 166.6 18.0 112.1 316.6 79.6 88.8 107.5 37.1 22.9 39.7 84.2 37.4 38.3 71.1 35.7 50.3 31.0 22.3 42.0 9.9 15.5 37.6 12.2 19.3 123.4 77.0 25.2 0.7 8.3 27.4 76.7 77.9 21.6 58.3 55.0 126.1 46.8 30.0 25.5 42.7 32.7 69.5 13.8 99.6 187.5 26.9 34.5 18.8 3.3 9.6 8.1 2.3 0.1 2.4 6.0 25.3 0.1 3.1 2.7 1.3 5.7 8.4 1.9 2.5 9.7 16.0 17.1 16.6 21.1 16.3 18.8 17.9 19.6 16.9 17.2 17.4 17.5 3.0 3.2 13.8 9.8 4.1 6.8 17.5 30.8 15.4 0.4 19.1 13.7 15.5 21.5 12.5 33.1 0.0 37.9 4.9 9.3 52.8 9.3 7.5 3.0 16.2 3.2 4.2 24.4 0.4 3.5 14.1 16.6 3.6 4.0 41.9 6.3 8.9 266.8 72.5 0.0 2.5 13.0 24.4 21.4 6.6 13.5 9.9 30.5 19.6 1.0 5.7 7.3 3.1 2.5 0.6 4.5 12.8 7.9 5.2 9.7 54.1 305.5 5.3 0.4 0.0 9.2 11.2 1.5 2.1 18.2 5.7 22.0 7.7 8.7 22.4 16.4 FAM13A "ARHGAP48, FAM13A1, KIAA0914" ENSG00000138640 "Family with sequence similarity 13 member A" O94988 4 88725955-89111398 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 178.0;Oligodendrocyte precursor cells: 157.8;Syncytiotrophoblasts: 279.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038108, HPA038109" Uncertain Approved "Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions, Cytosol" Nucleoli "HPA038108: AB_2675837, HPA038109: AB_10672619" "unprognostic (1.14e-1)" "unprognostic (1.53e-2)" "unprognostic (6.29e-2)" "unprognostic (2.53e-1)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (3.79e-1)" "unprognostic (2.81e-1)" "unprognostic (8.20e-2)" "unprognostic (1.75e-1)" "unprognostic (1.46e-3)" "unprognostic (6.36e-2)" "unprognostic (4.71e-1)" "unprognostic (3.49e-3)" "unprognostic (1.90e-2)" "unprognostic (7.44e-2)" "prognostic favorable (4.28e-4)" 49.2 12.8 8.5 9.9 9.0 12.7 31.8 14.2 11.8 17.6 13.2 18.3 50.5 12.5 7.5 7.6 23.5 16.3 9.9 9.7 7.3 21.9 39.1 11.8 6.3 8.6 8.4 27.8 38.6 49.2 8.4 35.1 9.5 10.6 14.8 15.9 23.4 10.5 9.7 20.4 29.0 13.3 8.3 5.4 16.3 13.9 9.0 5.6 32.8 21.9 4.8 16.9 10.4 8.8 4.5 6.7 9.8 12.8 55.5 22.7 16.0 10.2 12.4 4.0 3.6 5.6 10.3 0.1 4.0 7.4 6.3 2.7 14.5 7.4 8.9 0.6 10.0 7.5 8.9 0.7 16.3 6.3 1.0 21.9 5.9 10.1 3.6 17.5 6.9 2.5 19.7 0.7 8.7 0.2 0.7 2.8 12.1 0.8 6.9 10.2 16.6 4.0 7.4 21.8 24.6 6.5 2.5 7.9 9.9 9.6 5.5 0.2 2.5 11.2 6.2 5.5 5.9 3.4 2.1 0.1 16.6 0.6 5.9 0.0 4.1 0.0 1.0 2.0 0.7 0.0 2.7 0.3 3.5 0.0 2.9 0.7 0.9 0.4 0.6 1.2 1.5 1.6 8.5 9.0 14.2 11.8 9.7 7.3 8.6 8.4 9.5 8.3 9.0 8.8 42.6 12.8 34.9 95.3 4.3 10.1 22.3 20.4 28.5 16.3 29.7 20.6 25.9 38.6 39.3 11.0 35.5 72.9 12.9 50.4 29.4 10.7 3.4 82.0 33.6 14.1 4.9 31.3 178.0 16.9 35.3 42.1 33.1 98.2 1.3 70.2 12.8 143.0 20.7 0.0 46.5 54.1 26.4 29.6 11.9 5.1 45.1 21.7 19.6 104.9 16.9 22.6 5.2 157.8 17.4 20.7 73.4 33.4 10.3 13.6 37.5 50.4 74.6 11.3 0.0 24.7 31.9 5.3 10.2 14.4 7.7 279.5 9.7 41.2 22.3 19.5 FAM200B C4orf53 ENSG00000237765 "Family with sequence similarity 200 member B" P0CF97 4 15681662-15690447 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 406.9;Late spermatids: 306.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA017855 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 39: Non-specific - Basic cellular processes" "HPA017855: AB_1847703" "unprognostic (7.38e-2)" "unprognostic (5.05e-3)" "unprognostic (8.91e-2)" "unprognostic (1.95e-2)" "unprognostic (5.56e-2)" "unprognostic (8.00e-3)" "unprognostic (3.82e-1)" "prognostic favorable (9.89e-4)" "unprognostic (3.86e-2)" "unprognostic (2.23e-3)" "prognostic favorable (4.39e-4)" "unprognostic (3.46e-1)" "prognostic favorable (3.87e-4)" "unprognostic (6.44e-2)" "unprognostic (1.67e-2)" "unprognostic (1.28e-1)" "prognostic favorable (3.35e-5)" 6.4 6.8 12.8 5.1 13.7 3.7 7.2 13.7 17.2 6.8 9.7 5.1 6.6 6.4 9.3 4.7 6.2 5.0 5.2 12.8 13.4 10.3 8.9 4.2 5.5 12.0 13.0 8.5 5.5 5.8 6.5 6.5 12.1 6.1 5.6 8.9 4.6 6.0 5.5 4.8 5.7 3.8 12.4 5.4 4.4 4.8 15.0 9.6 8.9 6.6 3.9 4.1 4.9 15.0 6.3 9.2 14.6 8.0 10.2 13.5 5.2 7.7 4.3 10.0 9.0 6.8 4.3 7.4 3.9 8.4 13.1 4.4 14.5 7.4 15.6 3.7 8.0 5.7 12.3 10.7 8.1 5.4 2.4 7.9 8.4 9.7 6.1 16.9 5.7 4.7 7.6 4.4 22.1 3.6 5.6 5.9 19.4 3.6 7.3 5.0 22.5 1.1 9.2 4.9 20.0 11.0 5.6 1.6 13.6 12.8 3.3 6.6 8.1 10.3 8.1 8.4 10.5 2.1 4.6 3.5 6.4 7.2 23.5 3.7 6.7 6.8 1.4 3.0 1.9 0.8 1.7 1.3 3.3 1.3 2.9 2.3 15.1 1.1 2.4 1.1 2.1 3.7 12.8 13.7 13.7 17.2 12.8 13.4 12.0 13.0 12.1 12.4 15.0 15.0 35.2 28.9 47.5 16.0 21.7 53.8 61.8 80.0 76.8 53.4 72.8 96.1 94.9 78.6 52.4 77.3 12.5 72.4 34.8 54.3 406.9 50.1 224.1 64.6 46.1 42.9 66.0 27.1 23.4 58.7 60.2 59.0 17.9 62.9 13.3 64.5 44.3 91.9 68.2 53.8 23.5 68.5 97.6 77.3 48.6 306.0 93.8 60.4 62.2 5.6 84.7 133.3 59.8 10.6 39.4 51.9 79.3 70.0 8.5 45.4 105.2 233.8 55.1 21.1 46.0 48.1 56.7 113.4 38.0 45.4 51.1 34.6 38.8 71.2 66.7 64.7 FCGR1A "CD64, CD64A" ENSG00000150337 "Fc fragment of IgG receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 93.3;lymphoid tissue: 41.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 283.3;Kupffer cells: 140.9;Late spermatids: 64.9;Macrophages: 94.9" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 131.5;intermediate monocyte: 54.7;myeloid DC: 35.6;neutrophil: 93.4" "Group enriched" "Detected in many" 53 "dendritic cells: 35.6;granulocytes: 93.4;monocytes: 131.5" "Cell line enriched" "Detected in some" 5 "THP-1: 191.6" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" 12.2 7.2 8.4 41.3 8.9 17.9 3.6 8.8 12.8 4.2 8.4 2.3 1.1 1.6 93.3 1.7 1.8 8.2 2.2 8.6 9.4 2.8 4.2 28.6 14.4 14.6 10.6 2.3 4.3 2.7 2.5 32.6 13.0 1.6 2.1 2.3 1.9 2.4 0.3 0.4 1.3 19.1 13.2 12.5 2.1 3.7 12.2 1.4 1.4 0.8 0.8 14.7 0.8 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.3 191.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 24.4 0.0 2.0 131.5 1.6 0.0 54.7 0.7 1.6 0.0 0.3 35.6 0.0 0.0 0.1 93.4 0.0 11.8 0.9 0.3 48.5 8.4 8.9 8.8 12.8 8.6 9.4 14.6 10.6 13.0 13.2 12.2 18.9 0.3 0.0 3.1 0.0 0.8 0.1 0.0 0.0 0.6 1.5 0.2 0.8 1.7 1.5 1.3 0.0 2.1 2.7 0.0 0.0 0.0 0.0 30.8 0.1 0.1 9.3 0.0 2.7 0.1 0.0 1.3 1.0 0.0 0.1 0.0 0.2 1.8 0.5 283.3 0.0 0.1 0.0 0.0 140.9 6.0 64.9 0.3 94.9 0.0 7.5 34.7 0.3 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.7 1.3 6.6 0.2 0.3 0.6 0.4 0.1 0.0 4.1 0.6 0.1 0.1 0.0 FCGR1B CD64b ENSG00000198019 "Fc fragment of IgG receptor Ib" Q92637 1 121087345-121097161 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 86.5;Kupffer cells: 51.5;Late spermatids: 14.6;Macrophages: 36.6;monocytes: 16.4;Sertoli cells: 19.7" "Cancer enriched" "Detected in single" 4 "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 31.2;neutrophil: 36.3" "Group enriched" "Detected in many" 4 "granulocytes: 36.3;monocytes: 31.2" "Group enriched" "Detected in some" 6 "NB-4: 19.8;THP-1: 73.9" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (3.21e-2)" "unprognostic (4.35e-2)" "unprognostic (1.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (9.60e-2)" "unprognostic (1.56e-2)" "unprognostic (6.42e-2)" "unprognostic (3.10e-2)" "unprognostic (8.17e-2)" "unprognostic (1.91e-1)" "unprognostic (3.65e-1)" "unprognostic (3.24e-10)" "unprognostic (8.99e-2)" "unprognostic (2.85e-2)" "unprognostic (7.86e-3)" "unprognostic (8.93e-2)" 5.0 3.0 4.4 18.9 4.5 6.6 1.8 4.5 7.8 1.0 3.7 0.7 0.5 0.7 51.5 0.7 0.8 1.9 1.1 4.6 4.7 1.4 1.7 6.8 2.2 6.1 5.7 0.6 2.6 0.7 1.0 11.0 6.2 0.8 0.8 0.8 0.9 0.6 0.4 0.2 0.7 5.8 6.0 7.2 0.9 0.7 6.2 0.4 2.1 0.1 0.3 4.0 0.4 6.4 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 5.9 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 19.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.1 0.0 0.3 1.0 73.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 31.2 0.6 0.0 19.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 36.3 0.0 12.4 0.3 0.0 8.8 4.4 4.5 4.5 7.8 4.6 4.7 6.1 5.7 6.2 6.0 6.2 6.4 0.4 0.0 2.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.1 0.6 2.2 0.0 0.6 0.0 2.1 0.8 0.1 0.1 0.0 0.0 7.7 0.2 0.2 2.0 0.0 0.8 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.4 0.4 0.3 86.5 3.3 0.1 0.0 0.0 51.5 4.1 14.6 1.2 36.6 0.0 11.2 16.4 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.4 19.7 0.6 0.1 0.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.1 FCGRT "alpha-chain, FCRN" ENSG00000104870 "Fc fragment of IgG receptor and transporter" P55899 19 49506816-49526428 "Predicted intracellular proteins, Predicted membrane proteins" "IgG-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1362.6;Kupffer cells: 877.7;Paneth cells: 883.9;Proximal enterocytes: 1787.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2346.7" "Group enriched" "Detected in all" 17 "dendritic cells: 922.9;granulocytes: 2346.7;monocytes: 1364.4" "Cell line enhanced" "Detected in many" "ASC diff: 153.7;Hep G2: 144.0;OE19: 165.4;THP-1: 196.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012122, HPA015130" Enhanced NA NA 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA012122: AB_1848474, HPA015130: AB_1848475" "unprognostic (2.19e-3)" "unprognostic (2.05e-2)" "unprognostic (1.89e-1)" "unprognostic (1.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.26e-1)" "unprognostic (8.58e-2)" "unprognostic (3.87e-3)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (2.00e-3)" "unprognostic (3.64e-1)" "unprognostic (3.67e-3)" "unprognostic (3.40e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (2.18e-3)" 263.1 127.7 67.7 99.6 73.3 147.3 198.8 68.0 102.5 217.2 111.1 209.6 304.4 143.1 48.8 60.2 155.5 144.6 123.0 66.3 75.1 177.6 401.6 177.5 143.3 74.0 69.5 193.2 129.4 114.5 79.8 137.5 74.3 104.6 149.3 4.8 106.2 94.7 64.4 112.3 299.3 91.6 73.6 318.9 126.6 28.3 78.8 62.9 111.9 77.8 39.1 136.7 132.0 78.2 0.4 37.1 4.3 123.7 153.7 78.2 6.0 32.1 73.4 20.9 22.9 50.5 22.5 0.2 59.4 45.9 10.8 8.5 1.2 1.1 11.7 0.3 45.5 74.2 0.6 144.0 95.8 1.1 14.2 95.1 1.9 17.5 0.2 86.5 81.3 48.0 12.2 10.9 53.7 0.8 0.6 14.3 2.1 165.4 22.0 2.6 35.3 3.7 96.0 9.3 2.6 23.1 5.6 0.2 4.5 18.3 26.5 196.1 28.1 52.8 11.8 0.9 1.3 2.4 13.5 9.8 10.8 70.2 7.9 566.8 1364.4 1011.5 24.7 904.8 29.8 58.0 39.8 39.7 922.9 62.5 89.4 51.0 2346.7 28.6 630.2 536.4 28.2 1276.9 67.7 73.3 68.0 102.5 66.3 75.1 74.0 69.5 74.3 73.6 78.8 78.2 479.6 67.3 89.3 21.2 44.2 126.1 130.4 130.7 52.9 0.7 125.5 151.3 30.7 158.7 79.9 73.5 4.2 12.7 83.8 652.3 60.7 86.3 6.5 29.1 89.6 259.2 158.1 55.8 0.2 61.6 24.9 269.9 108.6 24.8 70.5 181.2 587.6 343.9 1362.6 0.0 0.2 349.0 57.0 877.7 438.1 21.8 362.2 608.6 186.7 24.4 190.6 13.4 11.3 10.1 0.2 90.6 883.9 183.6 63.2 87.9 1787.7 329.5 53.4 5.2 216.9 149.2 105.6 21.1 17.6 27.7 107.1 20.7 32.4 129.9 565.1 115.4 FCN1 FCNM ENSG00000085265 "Ficolin 1" O00602 9 134903232-134917912 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 158.9;lung: 46.2;lymphoid tissue: 96.3" "Group enriched" "Detected in many" 10 "Kupffer cells: 504.4;Macrophages: 542.4;monocytes: 1017.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "classical monocyte: 1699.8;intermediate monocyte: 1195.1" "Lineage enhanced" "Detected in all" "monocytes: 1699.8" "Group enriched" "Detected in some" 5 "NB-4: 4.7;U-937: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000685, HPA001295, CAB016760" Enhanced "Secreted to blood" NA NA 1060000000 36000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "CAB016760: , HPA000685: AB_1078840, HPA001295: AB_1078842" "unprognostic (1.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.14e-3)" "unprognostic (1.34e-1)" "unprognostic (9.91e-2)" "unprognostic (1.62e-3)" "unprognostic (3.66e-3)" "unprognostic (2.21e-1)" "unprognostic (1.14e-1)" "unprognostic (5.59e-2)" "unprognostic (2.49e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.73e-2)" "unprognostic (5.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.28e-1)" 15.9 1.4 0.6 47.7 0.5 158.9 5.1 0.8 0.7 2.0 0.5 3.2 0.5 1.5 0.0 1.6 6.4 3.9 5.1 0.5 0.3 4.1 7.2 46.2 3.2 0.5 0.5 1.0 2.5 0.1 1.0 2.4 0.6 2.3 1.6 0.1 2.8 0.5 1.6 1.2 2.8 12.1 0.2 96.3 3.7 0.7 0.7 2.4 2.2 1.1 1.3 10.1 2.3 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.1 0.0 0.1 0.0 7.2 0.1 9.3 1699.8 18.0 2.9 1195.1 3.5 5.9 1.4 1.6 492.6 1.5 1.7 1.6 277.1 2.8 582.2 13.0 2.1 1796.8 0.6 0.5 0.8 0.7 0.5 0.3 0.5 0.5 0.6 0.2 0.7 0.5 2.1 6.4 17.1 0.0 6.6 1.9 0.2 0.0 0.0 0.0 0.3 0.0 2.6 1.5 5.0 1.8 0.0 0.8 6.0 0.1 0.0 0.0 0.1 0.2 0.2 2.7 0.0 5.2 0.0 0.0 1.5 3.6 1.5 0.1 12.6 0.1 3.9 2.6 68.4 0.0 0.0 0.0 0.0 504.4 68.3 0.0 0.0 542.4 0.0 0.0 1017.8 0.0 27.8 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 2.1 0.7 0.0 0.0 1.0 0.5 0.0 0.1 0.2 0.4 1.1 6.1 0.3 0.0 0.2 FCN2 "EBP-37, FCNL, ficolin-2, P35" ENSG00000160339 "Ficolin 2" Q15485 9 134880810-134887523 "Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 99.7" "Cell type enriched" "Detected in some" 18 "Hepatic stellate cells: 1192.6" "Group enriched" "Detected in some" 8 "breast cancer: 1.0;liver cancer: 2.0;prostate cancer: 1.1;renal cancer: 0.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.5;intermediate monocyte: 4.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in some" 23 "spinal cord: 38.6" "Secreted to blood" NA NA 8100000000 1400000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.91e-1)" "unprognostic (1.07e-1)" "unprognostic (6.96e-4)" "unprognostic (3.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.81e-1)" "unprognostic (2.82e-1)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" "unprognostic (1.05e-1)" "unprognostic (3.07e-1)" 4.7 24.6 0.4 0.0 0.4 0.1 7.6 0.3 0.5 0.3 0.5 0.0 0.1 0.1 0.2 0.1 0.3 0.1 0.3 0.6 0.4 6.4 99.7 0.1 0.1 0.3 0.5 0.5 0.5 0.2 3.1 0.0 0.4 3.2 0.0 0.0 3.2 0.4 0.1 0.2 0.1 0.0 0.2 3.1 0.2 0.2 0.4 0.0 2.1 0.1 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.5 0.0 0.0 4.6 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 1.1 0.0 2.2 0.0 0.0 9.0 0.4 0.4 0.3 0.5 0.6 0.4 0.3 0.5 0.4 0.2 0.4 0.3 0.1 0.0 0.0 0.7 3.8 0.0 0.1 0.0 0.0 0.0 3.8 0.4 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 34.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1192.6 12.6 0.0 0.0 0.1 0.0 0.0 64.1 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 FFAR4 "GPR120, GPR129, O3FAR1, PGR4" ENSG00000186188 "Free fatty acid receptor 4" Q5NUL3 10 93566665-93604480 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Differentiation, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.4;pituitary gland: 11.0" "Cell type enriched" "Detected in some" 4 "Intestinal goblet cells: 125.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 12.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042563 Uncertain "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "HPA042563: AB_10794762" "unprognostic (1.96e-1)" "unprognostic (1.06e-2)" "unprognostic (1.14e-2)" "unprognostic (4.21e-2)" "unprognostic (2.12e-1)" "unprognostic (4.98e-4)" "unprognostic (1.41e-3)" "unprognostic (1.20e-2)" "unprognostic (2.34e-2)" "unprognostic (7.87e-2)" "unprognostic (9.51e-2)" "unprognostic (1.49e-1)" "unprognostic (3.85e-2)" "unprognostic (5.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" 4.1 0.4 1.2 0.7 1.3 0.1 1.3 0.6 1.2 0.1 0.3 8.3 0.5 0.0 0.0 0.2 1.0 0.5 0.3 1.0 1.8 0.1 0.4 3.6 0.2 0.6 0.8 0.0 0.6 0.1 11.0 0.1 0.5 0.1 11.4 0.2 0.1 0.0 0.3 0.9 0.6 0.2 0.3 0.1 0.5 1.5 2.6 0.3 0.1 0.1 0.1 0.1 0.0 0.7 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 12.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.2 1.2 1.3 0.6 1.2 1.0 1.8 0.6 0.8 0.5 0.3 2.6 0.7 0.2 0.0 0.5 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.2 0.8 0.4 7.2 0.6 0.0 0.0 0.2 0.0 28.1 0.0 0.8 27.8 0.1 0.0 0.3 20.9 0.0 3.2 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 7.4 0.0 2.0 125.7 0.0 7.2 4.4 16.7 0.6 7.6 1.8 3.7 0.5 0.0 0.0 0.0 0.3 0.9 23.0 0.0 0.0 0.3 0.3 0.0 0.0 0.2 0.0 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 5.9 0.3 FHOD1 FHOS ENSG00000135723 "Formin homology 2 domain containing 1" Q9Y613 16 67229387-67247481 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 88.1;skeletal muscle: 127.0" "Cell type enhanced" "Detected in many" "granulocytes: 40.6;Theca cells: 40.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HMC-1: 112.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024468 Approved Supported Cytosol NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "HPA024468: AB_1848568" "unprognostic (6.53e-3)" "prognostic unfavorable (9.57e-4)" "unprognostic (5.42e-2)" "unprognostic (2.14e-3)" "unprognostic (1.11e-1)" "unprognostic (2.18e-2)" "unprognostic (1.62e-1)" "unprognostic (1.81e-1)" "unprognostic (2.03e-1)" "unprognostic (1.50e-1)" "unprognostic (4.62e-2)" "unprognostic (4.27e-2)" "prognostic unfavorable (1.90e-8)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (3.14e-3)" "unprognostic (4.70e-2)" 16.9 16.9 3.6 9.6 3.5 6.2 13.2 3.5 4.0 9.6 4.6 9.3 5.9 8.5 1.6 4.5 7.9 5.5 10.4 3.4 3.3 10.5 3.3 26.6 8.5 4.1 4.0 14.7 7.7 3.7 5.4 8.9 3.9 8.8 4.2 0.3 8.4 3.9 127.0 6.2 9.7 5.8 4.0 88.1 7.2 5.0 4.8 4.1 16.8 29.8 5.9 7.4 6.7 3.8 12.0 31.6 11.8 9.8 46.1 27.9 39.2 24.9 19.8 27.2 26.3 22.3 15.7 14.1 17.5 18.0 8.8 14.7 13.5 20.0 13.5 11.3 21.7 63.1 13.9 24.5 12.2 26.3 112.1 34.8 2.6 42.2 4.1 24.3 43.0 19.9 32.9 9.3 17.6 41.0 18.1 48.3 17.6 11.0 10.0 20.3 25.9 33.8 8.7 4.9 3.7 19.2 38.2 22.4 22.5 11.7 23.8 21.1 51.6 37.4 22.0 24.0 20.3 29.9 32.0 20.7 76.1 24.7 34.7 0.3 0.7 0.1 0.2 0.2 0.3 0.0 0.3 0.2 0.4 0.1 0.1 0.1 0.5 0.3 0.2 0.2 0.3 0.6 3.6 3.5 3.5 4.0 3.4 3.3 4.1 4.0 3.9 4.0 4.8 3.8 18.0 12.8 21.6 4.6 7.2 5.7 1.8 2.0 3.4 1.8 11.5 8.0 13.8 10.0 5.9 5.5 8.4 8.7 11.4 16.9 0.0 3.6 1.1 3.5 8.1 22.3 9.1 8.6 2.5 5.9 4.7 10.9 5.6 4.7 40.6 12.0 25.0 0.8 17.1 1.7 2.2 13.1 2.0 20.3 19.7 1.1 10.5 19.8 3.6 17.8 18.9 2.9 10.3 2.0 0.6 7.4 6.1 10.9 7.1 3.1 6.3 1.4 3.9 1.2 26.3 4.2 15.7 19.0 12.3 5.6 3.7 1.9 13.3 40.3 13.8 1.7 FKBP5 "FKBP51, FKBP54, P54, PPIase, Ptg-10" ENSG00000096060 "FKBP prolyl isomerase 5" Q13451 6 35573585-35728583 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 892.7;tongue: 925.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 759.3;ASC TERT1: 468.5;HHSteC: 593.0;HSkMC: 718.3;hTCEpi: 368.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009315, HPA031092, HPA031093, HPA031095" Enhanced Enhanced Nucleoplasm No No 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB009315: AB_2278350, HPA031092: AB_10600195, HPA031093: AB_10601748, HPA031095: AB_2673734" "unprognostic (2.09e-3)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.72e-1)" "unprognostic (6.30e-3)" "unprognostic (3.70e-3)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (7.48e-3)" "unprognostic (2.18e-3)" "unprognostic (8.31e-2)" "unprognostic (4.22e-2)" "unprognostic (6.90e-3)" 400.1 92.3 18.2 70.1 26.8 26.6 160.4 19.7 32.1 86.4 20.2 110.9 11.3 97.5 63.0 130.6 104.6 78.9 93.7 16.8 20.7 108.8 144.5 92.7 166.7 22.7 23.8 122.1 200.4 227.0 52.9 28.5 23.5 85.0 37.1 25.6 61.0 49.8 892.7 114.0 135.7 81.8 17.0 105.6 129.0 41.4 22.1 229.4 97.2 925.1 80.3 108.9 109.1 26.2 40.0 17.1 73.1 109.7 759.3 468.5 1.2 21.2 1.0 13.6 31.0 29.7 6.9 195.3 19.5 4.1 11.8 0.6 44.1 93.2 32.0 77.7 41.6 84.0 14.1 41.7 593.0 53.3 8.3 718.3 368.6 23.7 220.5 14.8 80.1 38.8 91.3 77.1 144.3 25.3 222.5 99.6 18.9 8.7 12.3 97.7 19.1 95.4 60.2 23.7 27.7 16.8 17.3 19.8 4.2 15.9 108.4 62.2 178.7 19.3 17.3 2.8 29.7 34.9 42.9 243.5 6.6 102.3 7.6 57.6 105.0 70.0 64.4 92.3 78.0 9.7 90.6 68.5 107.5 12.5 133.4 96.7 85.1 45.2 46.8 32.0 37.2 158.5 18.2 26.8 19.7 32.1 16.8 20.7 22.7 23.8 23.5 17.0 22.1 26.2 180.2 12.8 11.3 23.2 42.9 17.6 59.2 20.1 37.0 1.9 32.0 20.8 131.8 74.4 14.2 5.5 0.0 1.2 102.0 14.3 23.5 0.6 9.8 55.7 76.1 57.9 20.9 102.2 25.9 7.9 0.8 97.5 18.8 79.2 38.5 54.7 117.1 225.6 35.1 0.0 2.8 35.5 34.6 384.2 44.8 22.0 160.9 192.2 7.2 66.5 110.3 4.6 44.3 16.6 26.3 2.9 19.3 218.6 66.4 49.9 157.0 27.4 18.2 22.6 144.7 188.1 106.8 14.9 19.1 37.5 21.3 0.4 128.7 2.8 39.5 22.2 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FLVCR2 "C14orf58, CCT, FLJ20371, MFSD7C, SLC49A2" ENSG00000119686 "FLVCR heme transporter 2" Q9UPI3 14 75578620-75663214 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 75.6;Kupffer cells: 44.9;Late spermatids: 142.5;Microglial cells: 41.2;Proximal enterocytes: 50.4;Syncytiotrophoblasts: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 14.0;intermediate monocyte: 14.6;myeloid DC: 7.6;non-classical monocyte: 11.8" "Group enriched" "Detected in many" 7 "dendritic cells: 7.6;monocytes: 14.6" "Cell line enhanced" "Detected in many" "ASC diff: 53.8;ASC TERT1: 23.2;BEWO: 73.5;MCF7: 26.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037984 Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "HPA037984: AB_10672733" "unprognostic (2.42e-1)" "unprognostic (4.85e-2)" "unprognostic (4.19e-2)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "unprognostic (4.44e-2)" "unprognostic (8.72e-2)" "unprognostic (2.78e-1)" "unprognostic (3.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.22e-1)" "unprognostic (4.80e-2)" "prognostic favorable (2.53e-5)" "unprognostic (6.69e-2)" "unprognostic (9.94e-2)" "unprognostic (9.38e-2)" "unprognostic (1.16e-1)" 5.1 13.6 3.5 9.3 3.7 5.4 2.5 3.2 3.8 2.1 16.2 8.4 17.4 1.0 1.4 2.9 1.9 3.5 2.2 2.9 2.7 11.3 20.5 16.2 5.3 4.7 3.7 2.2 0.6 2.1 3.4 10.3 3.9 2.3 7.1 0.7 12.7 1.7 8.3 5.7 24.4 4.2 5.2 13.8 0.9 21.1 4.8 1.2 3.2 1.6 5.0 4.9 2.6 5.5 3.7 2.8 0.8 4.0 53.8 23.2 73.5 0.7 3.1 3.3 2.6 6.2 0.4 0.0 0.2 0.2 5.4 0.4 9.8 0.2 1.3 19.3 0.6 0.1 2.8 13.3 4.3 0.1 0.6 10.9 7.7 4.0 2.4 0.1 0.8 0.3 0.2 0.5 10.1 26.4 0.2 1.9 1.6 1.1 4.4 0.1 2.6 0.0 3.5 5.1 0.0 0.1 2.0 8.1 1.6 4.6 4.5 10.1 8.8 4.0 1.4 2.0 0.1 0.6 1.1 0.0 11.4 2.5 0.7 0.0 14.0 0.7 0.4 14.6 1.1 0.0 1.1 0.3 7.6 0.1 0.8 0.2 0.5 0.5 11.8 0.1 1.6 4.1 3.5 3.7 3.2 3.8 2.9 2.7 4.7 3.7 3.9 5.2 4.8 5.5 0.3 6.4 6.4 2.6 0.5 0.6 0.3 0.4 0.6 0.0 1.5 0.6 0.8 0.0 3.2 3.7 0.0 23.2 1.7 14.0 0.0 0.1 75.6 2.1 3.9 2.5 0.0 0.0 0.2 0.2 31.0 2.2 0.0 2.7 1.3 0.2 1.8 21.1 16.4 0.0 0.2 2.2 4.1 44.9 5.6 142.5 3.4 19.0 0.0 41.2 10.1 1.3 2.1 0.0 0.2 0.1 3.2 1.9 0.5 0.8 50.4 7.0 0.3 0.3 0.0 0.4 0.3 2.4 1.3 0.2 0.9 54.5 1.2 2.3 5.5 0.2 FOLR2 FRβ ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 168.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 1114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.2;intermediate monocyte: 50.6" "Group enriched" "Detected in many" 4 "dendritic cells: 18.7;monocytes: 64.2" "Cell line enriched" "Detected in some" 5 "U-698: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 15000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.03e-1)" "unprognostic (6.58e-3)" "prognostic unfavorable (8.42e-4)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-1)" "unprognostic (3.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.98e-3)" 119.1 55.0 10.7 28.2 11.0 10.8 31.7 8.2 18.6 27.9 13.8 36.0 19.5 13.5 12.4 31.6 16.8 80.1 38.6 10.9 9.5 10.8 44.8 39.7 78.5 9.3 10.7 16.0 7.1 7.9 6.1 168.4 11.4 6.1 46.7 0.2 12.8 16.7 5.9 9.8 29.6 46.3 9.3 27.7 21.0 13.0 16.2 28.7 9.1 26.3 29.0 81.3 6.3 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.2 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 0.0 0.2 0.0 18.6 0.5 0.8 0.0 0.0 64.2 0.0 0.3 50.6 0.0 9.5 0.0 0.0 18.7 4.0 0.0 0.0 1.1 1.8 13.7 0.2 0.0 20.4 10.7 11.0 8.2 18.6 10.9 9.5 9.3 10.7 11.4 9.3 16.2 16.1 3.4 0.0 0.6 0.0 8.0 7.9 0.1 0.0 1.2 0.0 0.1 1.1 2.2 1.5 0.0 0.0 0.0 7.6 0.6 0.0 0.0 0.0 0.9 0.3 0.1 2.3 0.0 0.0 0.0 0.0 6.0 2.4 0.0 0.5 2.5 0.0 2.2 1.7 1114.8 0.0 0.0 0.0 0.0 229.3 98.8 2.5 1.5 199.4 0.0 15.9 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.1 0.1 0.0 0.2 0.0 0.3 0.0 2.5 1.2 0.6 0.7 1.3 5.1 16.0 1.2 0.1 0.0 0.1 FOLR3 "FR-G, FRγ" ENSG00000110203 "Folate receptor gamma" P41439 11 72114869-72139892 "Metabolic proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 98.7;lymphoid tissue: 28.4" "Group enriched" "Detected in some" 10 "Distal tubular cells: 406.9;monocytes: 103.0" "Cancer enhanced" "Detected in some" "ovarian cancer: 5.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "classical monocyte: 330.8;neutrophil: 492.8" "Group enriched" "Detected in many" 11 "granulocytes: 492.8;monocytes: 330.8" "Group enriched" "Detected in some" 5 "hTERT-HME1: 72.4;U-2197: 64.7" "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.47e-2)" "unprognostic (6.26e-3)" "unprognostic (1.94e-2)" "unprognostic (8.72e-3)" "unprognostic (6.87e-3)" "unprognostic (9.56e-2)" "unprognostic (1.58e-1)" "unprognostic (3.72e-1)" "unprognostic (1.72e-1)" "unprognostic (1.54e-1)" "unprognostic (7.35e-2)" "unprognostic (7.90e-2)" "unprognostic (8.39e-2)" "unprognostic (9.99e-4)" "unprognostic (1.96e-1)" "unprognostic (2.03e-6)" "unprognostic (4.17e-1)" 5.7 0.4 0.3 10.6 0.2 98.7 0.2 0.2 0.5 0.2 0.3 0.2 0.4 0.0 0.0 1.0 0.9 0.3 0.5 0.2 0.3 8.6 0.8 5.9 0.1 0.3 0.3 0.0 0.2 0.0 0.1 0.7 0.3 0.2 0.1 0.0 0.6 0.1 0.1 0.6 0.5 0.6 0.2 28.4 0.4 0.9 0.6 1.3 1.7 0.5 0.0 0.5 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.3 10.4 13.1 3.7 9.2 0.0 0.0 0.0 1.3 2.0 0.2 1.1 0.0 6.9 8.4 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 8.8 5.4 72.4 1.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.6 0.3 64.7 0.0 0.1 0.0 0.0 2.7 0.0 0.0 15.1 330.8 30.9 0.5 26.1 1.8 0.3 0.1 0.2 36.2 0.1 0.1 0.0 492.8 0.5 1.4 6.3 0.4 294.4 0.3 0.2 0.2 0.5 0.2 0.3 0.3 0.3 0.3 0.2 0.6 0.3 0.1 0.0 7.9 0.0 1.1 0.3 0.0 0.9 0.0 0.0 0.1 0.0 0.1 0.0 1.9 23.9 0.0 0.1 1.3 0.0 406.9 0.1 3.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 3.8 0.0 1.1 0.0 1.6 0.0 0.0 0.0 0.0 22.4 1.7 10.9 0.0 17.4 0.0 0.0 103.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 18.1 1.5 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 1.0 0.1 0.0 0.1 FRMD4B "GRSP1, KIAA1013" ENSG00000114541 "FERM domain containing 4B" Q9Y2L6 3 69168782-69542583 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 84.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1209.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 39.8;hTERT-HME1: 52.7;HUVEC TERT2: 55.1;TIME: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009705 Uncertain Supported Approved "Nucleoplasm,Golgi apparatus,Centriolar satellite" NA NA 17000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Centriolar satellite" "Nucleoplasm, Golgi apparatus" "HPA009705: AB_1849147" "unprognostic (1.36e-1)" "unprognostic (2.92e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (4.59e-2)" "unprognostic (9.73e-2)" "unprognostic (1.49e-1)" "unprognostic (2.02e-1)" "unprognostic (2.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.09e-2)" "unprognostic (8.23e-2)" "prognostic favorable (5.01e-4)" "unprognostic (1.49e-1)" "unprognostic (7.54e-2)" "unprognostic (2.79e-1)" "unprognostic (4.39e-3)" 11.0 4.8 17.5 12.3 46.7 15.5 16.1 26.9 30.9 24.9 7.0 12.8 9.1 11.3 9.3 26.8 13.2 19.2 17.4 20.8 29.3 16.3 34.5 24.8 10.9 39.4 37.1 10.9 8.2 3.7 4.0 25.5 36.3 16.9 12.9 21.9 37.1 10.5 2.3 23.0 12.5 10.5 22.7 32.3 15.0 4.7 42.0 14.1 27.1 4.6 11.2 13.7 15.8 84.0 6.7 1.8 10.4 0.3 0.2 1.5 11.3 0.5 1.7 0.8 0.5 39.8 11.3 0.8 3.5 0.5 1.0 25.9 4.9 35.3 1.2 2.2 3.3 20.4 2.6 2.3 0.7 5.2 10.2 1.7 35.2 1.0 52.7 1.6 55.1 4.7 1.6 5.8 3.0 7.7 0.5 0.8 5.6 8.9 8.5 32.2 2.8 1.0 14.8 4.6 12.1 15.6 1.7 12.2 35.5 9.3 4.6 6.8 47.1 0.6 4.3 0.4 1.8 0.6 0.3 1.2 0.4 13.5 13.5 18.3 27.6 2.3 1.9 13.8 7.0 1.6 6.3 2.8 16.9 2.0 1.9 1.8 7.1 3.8 2.3 16.8 15.4 7.7 17.5 46.7 26.9 30.9 20.8 29.3 39.4 37.1 36.3 22.7 42.0 84.0 20.6 41.7 83.6 2.9 3.6 60.7 33.4 57.8 69.4 13.8 34.4 21.7 33.4 41.5 58.5 14.7 218.9 49.9 20.3 74.4 33.2 32.6 18.9 207.9 49.3 64.3 24.5 8.6 4.2 17.3 19.7 32.1 75.4 282.6 34.7 97.5 89.3 53.6 92.6 0.0 92.7 42.1 36.7 138.7 112.7 4.0 6.5 105.2 28.4 93.7 26.3 13.5 1.0 129.2 1209.1 24.5 67.0 18.4 6.9 61.1 10.7 55.6 38.2 109.2 6.6 11.8 21.0 0.0 3.5 79.9 51.4 58.3 44.6 32.1 32.2 172.8 FUCA2 "dJ20N2.5, MGC1314" ENSG00000001036 "Alpha-L-fucosidase 2" Q9BTY2 6 143494812-143511720 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 165.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031659, HPA031661" Approved "Secreted to blood" NA NA 56000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA031659: AB_10600661, HPA031661: AB_10601681" "unprognostic (1.83e-2)" "unprognostic (1.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (2.70e-9)" "unprognostic (1.54e-3)" "unprognostic (1.08e-1)" "unprognostic (7.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.90e-1)" "unprognostic (8.76e-3)" "unprognostic (9.18e-2)" "unprognostic (2.69e-1)" "unprognostic (7.25e-2)" "unprognostic (5.07e-2)" 28.9 41.4 13.5 25.4 16.4 25.8 26.3 16.0 15.3 29.2 30.2 41.5 42.6 25.6 44.9 14.2 23.7 27.8 27.9 12.4 16.5 54.8 52.3 28.9 17.2 17.1 14.2 30.4 34.6 165.8 15.8 50.5 17.8 21.9 52.8 6.1 25.4 25.8 6.9 12.3 39.3 27.6 16.4 24.6 38.3 12.6 15.9 6.6 32.0 11.6 17.0 33.5 20.4 20.9 97.4 55.7 47.6 86.9 69.0 134.4 90.1 89.9 95.4 108.1 182.0 107.1 94.8 0.2 66.1 120.8 33.9 0.6 24.1 11.7 148.9 87.2 92.6 32.6 100.1 163.2 99.3 0.3 15.8 72.3 69.4 96.6 41.5 91.6 111.4 0.2 117.6 49.3 123.2 114.6 0.2 75.9 62.1 44.2 76.0 0.2 99.7 72.1 129.0 59.5 36.0 23.6 98.7 65.3 82.3 36.3 32.1 79.6 65.9 64.1 54.0 161.6 175.4 18.3 21.3 0.7 74.1 59.1 22.5 38.8 84.9 26.2 13.2 84.0 15.0 11.3 9.8 11.3 65.4 8.3 4.4 7.9 5.5 29.6 62.0 10.3 19.8 51.9 13.5 16.4 16.0 15.3 12.4 16.5 17.1 14.2 17.8 16.4 15.9 20.9 27.3 41.7 35.9 9.1 13.5 11.2 12.6 30.3 9.1 3.7 19.2 12.6 28.0 38.6 37.9 25.8 0.0 52.5 10.3 47.6 11.7 81.9 2.0 26.8 55.2 25.0 9.6 18.7 8.7 124.9 109.8 62.6 34.7 28.9 37.4 38.1 23.6 35.2 110.3 1.7 11.8 38.1 46.8 57.5 29.2 2.6 66.8 51.7 42.7 9.4 49.1 11.1 13.4 5.5 14.5 74.6 38.2 45.5 47.7 13.8 60.3 51.4 34.8 1.1 6.6 33.8 35.0 4.8 4.6 13.2 8.0 46.4 11.5 78.8 50.4 18.4 FUOM "C10orf125, FLJ26016, FucM, FucU" ENSG00000148803 "Fucose mutarotase" A2VDF0 10 133355158-133358025 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 228.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 564.7;Hofbauer cells: 172.0;Proximal enterocytes: 690.7;Proximal tubular cells: 368.1" "Cancer enriched" "Detected in all" 5 "liver cancer: 61.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039207 Approved NA NA 2000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "HPA039207: AB_10795033" "unprognostic (1.15e-2)" "unprognostic (1.16e-1)" "unprognostic (4.48e-2)" "unprognostic (7.19e-2)" "unprognostic (4.82e-1)" "unprognostic (2.66e-2)" "unprognostic (1.66e-2)" "unprognostic (2.45e-1)" "unprognostic (6.25e-2)" "unprognostic (7.56e-2)" "unprognostic (4.50e-2)" "unprognostic (8.67e-2)" "unprognostic (3.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" "unprognostic (1.65e-1)" 12.9 8.8 4.2 11.3 4.4 6.6 13.0 4.0 7.2 7.3 8.2 12.0 52.0 5.5 3.2 8.7 7.9 9.6 17.4 4.2 4.6 46.7 228.3 14.1 16.8 5.3 4.7 7.3 18.3 8.0 6.0 5.2 5.7 7.0 5.4 0.3 28.8 3.6 3.0 7.4 46.8 3.6 4.9 23.7 8.5 5.6 5.1 6.1 6.6 2.6 8.0 7.9 7.7 4.8 23.3 7.2 13.6 28.4 3.8 9.2 24.8 18.3 20.7 6.5 8.1 46.4 12.4 0.0 20.7 13.8 0.0 1.2 4.9 6.3 0.5 8.4 4.9 22.3 10.3 50.7 20.1 25.2 14.8 9.6 0.2 2.6 1.4 3.0 9.2 22.9 22.2 29.7 13.9 23.0 3.9 33.6 9.5 13.5 3.2 21.8 0.4 13.0 7.5 0.0 1.4 11.0 6.7 20.6 25.3 6.8 0.2 38.3 18.7 0.1 18.4 0.0 0.1 15.5 2.7 16.7 5.5 10.2 7.1 0.1 68.9 6.5 16.0 73.2 14.7 36.0 14.0 13.4 57.2 34.5 14.9 13.1 3.3 17.1 15.7 79.0 10.4 28.6 4.2 4.4 4.0 7.2 4.2 4.6 5.3 4.7 5.7 4.9 5.1 4.8 20.4 6.4 10.0 0.0 32.7 12.1 9.2 8.5 6.2 0.1 12.2 25.7 10.9 22.8 11.4 9.2 0.0 10.3 25.1 79.2 31.3 13.6 3.7 3.8 9.7 14.1 3.0 24.4 0.6 12.7 9.0 25.6 8.6 7.7 27.3 15.5 25.0 564.7 172.0 0.0 1.2 49.7 6.1 103.0 55.4 10.3 10.2 68.7 26.6 1.9 85.6 3.5 13.4 0.0 1.0 12.5 119.5 3.8 29.6 17.8 690.7 368.1 4.0 1.1 13.1 11.6 14.9 20.2 23.7 10.0 9.9 6.6 21.5 4.1 61.1 12.1 FXYD6 ENSG00000137726 "FXYD domain containing ion transport regulator 6" Q9H0Q3 11 117836976-117877486 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 163.9;Leydig cells: 237.9;Muller glia cells: 128.7;Peritubular cells: 363.8;Sertoli cells: 355.0;Theca cells: 141.8" "Cancer enriched" "Detected in all" 6 "glioma: 71.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "classical monocyte: 37.7" "Lineage enriched" "Detected in many" 6 "monocytes: 37.7" "Cell line enhanced" "Detected in some" "AF22: 136.0;HAP1: 92.9;RH-30: 57.1;SCLC-21H: 204.5;SH-SY5Y: 114.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041334, HPA042284" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA041334: AB_10970752, HPA042284: AB_2677931" "unprognostic (2.18e-3)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.31e-2)" "unprognostic (1.15e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.51e-2)" "unprognostic (3.78e-2)" "unprognostic (1.07e-2)" "prognostic favorable (5.97e-4)" "unprognostic (3.44e-2)" "prognostic favorable (4.38e-5)" "unprognostic (4.64e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.60e-4)" 58.4 116.3 230.8 30.1 258.5 9.8 39.5 82.5 293.2 112.3 28.1 371.1 22.2 321.5 61.0 29.8 181.6 93.1 117.1 244.3 187.3 70.6 32.8 86.6 30.0 91.8 173.6 281.1 30.1 9.8 175.0 16.7 149.5 107.8 35.9 47.1 29.5 73.2 37.3 22.2 104.6 197.6 71.4 151.9 98.9 86.6 136.4 31.2 66.5 78.3 18.9 202.9 80.4 179.3 0.3 0.9 136.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.6 0.1 4.8 0.7 92.9 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.3 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.2 2.6 0.0 1.7 6.3 0.5 27.2 0.0 0.0 0.1 57.1 1.0 3.5 0.1 204.5 114.0 0.0 0.5 5.1 36.9 2.4 2.4 0.0 0.0 30.0 0.5 0.0 0.4 0.3 0.1 1.0 0.4 0.4 0.0 37.7 0.0 0.0 9.4 0.6 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.9 0.0 0.1 0.6 0.0 9.9 230.8 258.5 82.5 293.2 244.3 187.3 91.8 173.6 149.5 71.4 136.4 179.3 72.2 6.4 2.2 0.0 1.1 6.6 2.4 1.1 0.6 3.5 2.1 21.5 9.3 1.5 0.7 0.0 2.1 0.8 1.0 0.0 1.9 6.4 3.6 0.6 23.9 71.8 12.5 10.7 0.0 0.4 1.1 78.6 0.5 1.0 0.0 29.7 163.9 1.6 72.7 1.7 0.0 0.2 6.1 32.4 9.6 14.3 237.9 18.7 16.0 0.0 9.8 128.7 1.0 0.0 0.0 0.4 0.0 363.8 1.2 4.9 0.0 0.1 1.7 4.4 355.0 49.6 79.6 4.6 3.5 1.4 3.8 1.4 1.4 141.8 0.0 1.7 GAPDH GAPD ENSG00000111640 "Glyceraldehyde-3-phosphate dehydrogenase" P04406 12 6534512-6538374 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Glycolysis, Immunity, Innate immunity, Translation regulation" "Oxidoreductase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 27580.7;tongue: 18892.5" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 10357.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "CAB005197, CAB016392, HPA040067, HPA061280, CAB079968" Supported Enhanced "Nuclear membrane,Vesicles,Plasma membrane,Cytosol" No No 1400000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "Nuclear membrane, Vesicles" "CAB005197: AB_641107, CAB016392: AB_627678, CAB079968: , HPA040067: AB_10965903, HPA061280: AB_2684463" "unprognostic (3.03e-1)" "unprognostic (2.62e-3)" "unprognostic (3.58e-2)" "unprognostic (4.20e-1)" "unprognostic (9.73e-3)" "unprognostic (1.77e-3)" "prognostic unfavorable (1.79e-6)" "unprognostic (2.89e-3)" "unprognostic (2.86e-1)" "unprognostic (2.06e-2)" "unprognostic (9.50e-3)" "unprognostic (4.52e-1)" "prognostic unfavorable (6.25e-10)" "unprognostic (2.33e-1)" "unprognostic (4.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.26e-2)" 1219.9 1815.8 2605.9 1191.3 2589.5 4608.5 1042.3 2869.0 3067.8 1163.8 2419.2 1720.0 1480.8 1080.9 769.9 2973.8 1042.8 1161.3 5572.8 2630.1 2880.0 2323.2 2557.9 1137.9 1388.3 2845.2 2861.3 1087.0 652.0 1616.0 1338.7 1190.6 2828.4 1241.0 1586.6 2386.8 1835.8 1238.7 27580.7 1775.5 1457.5 1424.4 2670.8 1208.5 1215.5 693.0 2985.1 1570.9 1022.1 18892.5 1861.0 1889.0 1672.9 2741.6 6063.0 10247.9 3109.5 4709.2 3026.2 5018.7 6516.0 4716.2 7218.1 7172.8 7491.2 7211.3 4091.6 7540.8 878.2 5947.4 4904.2 3359.8 3372.7 10829.1 5432.4 6263.1 3229.5 4224.9 5857.5 6279.2 3890.9 6710.2 3046.1 4089.0 3521.7 6553.0 7609.7 15565.8 7762.7 5052.4 2215.9 1484.1 8670.0 11849.8 7303.1 3247.3 10995.7 7254.7 3950.7 5849.8 5505.7 3512.8 7909.6 7115.9 2088.3 3331.0 4243.1 10206.4 5984.0 8874.7 1657.2 4311.2 4794.3 5049.0 5907.2 2717.1 7931.5 3178.4 2544.6 9374.4 10632.2 4050.5 8040.5 2575.4 4295.8 737.9 1325.8 2011.2 1171.4 1046.9 1364.8 1333.1 3253.6 652.5 757.6 886.9 1981.4 1227.8 1900.6 474.6 2126.1 6812.0 2605.9 2589.5 2869.0 3067.8 2630.1 2880.0 2845.2 2861.3 2828.4 2670.8 2985.1 2741.6 1036.7 237.2 259.5 228.2 1086.9 1818.8 2223.4 7367.5 4070.9 1157.6 1794.6 3689.2 40.4 1263.9 2213.7 1022.5 417.0 4237.7 1032.7 2579.6 3463.0 5198.9 759.8 770.1 702.4 1597.4 1324.3 1180.6 112.1 3794.5 10357.8 1127.1 1068.8 1021.8 562.3 2063.7 1242.9 1742.3 3895.3 2348.7 145.8 2351.2 2543.1 2586.7 2494.4 2257.7 889.4 2134.0 4220.8 86.2 3422.3 6177.9 1045.4 98.5 196.2 5681.8 3001.4 1026.9 2668.2 1714.0 5714.0 7286.7 864.3 1435.2 1150.4 1744.7 2827.8 429.9 476.2 3605.2 1600.7 4694.0 1514.9 1839.0 3140.9 2882.4 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GASK1B "C4orf18, DKFZp434L142, ENED, FAM198B, FLJ38155" ENSG00000164125 "Golgi associated kinase 1B" Q6UWH4 4 158124474-158173318 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 206.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.9;Cardiomyocytes: 33.8;Endothelial cells: 12.1;Fibroblasts: 14.5;Hofbauer cells: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "classical monocyte: 50.6;intermediate monocyte: 28.8;myeloid DC: 15.1;non-classical monocyte: 14.0" "Group enriched" "Detected in many" 41 "dendritic cells: 15.1;monocytes: 50.6" "Cell line enhanced" "Detected in many" "ASC diff: 77.0;ASC TERT1: 143.3;HSkMC: 166.4;HUVEC TERT2: 193.3;WM-115: 74.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007227 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA 13000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA007227: AB_1847689" "unprognostic (4.87e-2)" "unprognostic (7.79e-2)" "unprognostic (6.60e-3)" "unprognostic (9.42e-3)" "unprognostic (2.37e-2)" "unprognostic (7.47e-2)" "unprognostic (2.13e-2)" "unprognostic (7.49e-2)" "unprognostic (9.20e-3)" "unprognostic (1.71e-1)" "unprognostic (1.60e-1)" "unprognostic (1.89e-1)" "unprognostic (3.25e-3)" "unprognostic (3.74e-3)" "unprognostic (3.85e-2)" "unprognostic (1.14e-2)" "unprognostic (1.89e-2)" 73.9 206.2 29.0 39.8 29.2 2.8 47.3 21.8 23.3 47.0 11.9 23.4 13.3 77.7 21.8 17.2 19.4 37.1 77.9 28.7 29.6 9.5 8.6 14.1 11.2 51.7 33.0 140.3 14.2 11.5 2.8 29.0 26.9 23.6 23.3 0.8 23.6 30.0 12.4 7.3 18.5 70.2 34.1 20.8 11.8 10.4 35.5 5.7 17.7 16.7 6.8 43.2 9.2 33.0 12.5 9.9 6.1 1.1 77.0 143.3 11.4 3.1 2.4 0.6 3.7 13.3 4.9 0.1 0.3 5.0 5.1 0.2 70.7 18.9 1.8 0.1 0.2 1.0 0.0 37.0 51.4 0.6 0.3 166.4 4.6 24.2 2.6 8.0 193.3 0.0 13.0 0.0 35.7 0.8 0.0 0.2 0.4 43.4 0.2 0.1 0.5 0.2 0.0 27.5 0.4 0.1 0.0 27.8 8.2 33.4 5.4 0.3 9.3 16.0 17.1 9.6 6.1 0.0 0.1 44.8 2.5 0.3 74.3 0.1 50.6 0.0 0.1 28.8 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.7 0.1 14.0 0.6 0.0 17.8 29.0 29.2 21.8 23.3 28.7 29.6 51.7 33.0 26.9 34.1 35.5 33.0 22.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 1.2 14.5 0.0 0.0 0.0 0.0 0.0 0.0 67.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 GGTA1 "GGTA, GGTA1P, GLYT2" ENSG00000204136 "Glycoprotein alpha-galactosyltransferase 1 (inactive)" Q4G0N0 9 121444991-121499844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 133.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Endothelial cells: 2.2;granulocytes: 3.8;Macrophages: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 22.7;intermediate monocyte: 17.9;myeloid DC: 12.7;plasmacytoid DC: 27.5" "Group enriched" "Detected in many" 19 "dendritic cells: 27.5;monocytes: 22.7" "Group enriched" "Detected in some" 6 "AN3-CA: 4.3;HEL: 1.3;SH-SY5Y: 4.9" HPA023262 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "HPA023262: AB_1849651" "unprognostic (1.71e-1)" "unprognostic (9.98e-2)" "unprognostic (4.49e-2)" "prognostic favorable (5.33e-5)" "unprognostic (1.67e-2)" "unprognostic (2.85e-2)" "unprognostic (8.98e-2)" "unprognostic (1.34e-2)" "unprognostic (2.43e-1)" "unprognostic (1.29e-1)" "unprognostic (7.85e-2)" "unprognostic (1.63e-1)" "unprognostic (5.53e-3)" "unprognostic (9.24e-2)" "unprognostic (2.64e-2)" "unprognostic (1.44e-2)" "unprognostic (6.87e-2)" 33.4 18.5 15.4 10.1 18.9 68.2 40.4 12.7 19.9 17.2 14.4 14.9 12.0 10.7 7.4 24.2 10.1 23.1 18.7 16.4 15.3 5.7 15.0 21.9 25.7 13.9 15.2 7.6 5.0 4.8 41.7 13.7 6.5 15.4 0.5 133.2 15.3 5.0 13.6 16.1 12.5 14.1 40.4 8.7 4.1 16.0 9.9 5.1 13.4 10.4 21.4 14.9 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.7 0.0 0.0 17.9 0.0 0.7 0.0 0.0 12.7 0.0 0.0 0.0 1.2 0.1 0.4 27.5 0.0 7.2 15.4 18.9 12.7 19.9 16.4 15.3 13.9 15.2 13.7 14.1 16.0 14.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996609-33097202 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 857.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 22.0 36.1 12.1 27.8 13.0 21.9 20.5 12.5 14.8 33.4 16.0 43.5 43.0 21.9 103.6 15.4 28.2 32.0 15.5 12.5 14.8 46.0 48.2 42.7 25.8 14.3 12.9 21.4 30.8 59.4 18.5 53.8 15.4 23.2 45.6 14.9 25.3 29.3 7.7 15.8 31.0 30.6 12.4 24.4 35.5 13.5 13.5 17.5 52.8 10.8 23.0 31.8 16.2 15.1 37.4 63.6 39.8 48.3 241.9 123.7 857.2 59.1 157.6 73.7 95.1 91.3 86.5 17.9 50.9 120.9 53.9 35.1 38.1 75.5 53.7 104.9 33.0 69.9 35.3 47.4 124.3 50.5 69.9 144.9 70.2 67.0 39.2 144.1 116.5 24.7 64.3 67.0 81.8 44.6 29.6 31.6 26.4 78.0 27.0 24.7 26.4 86.6 78.4 54.4 12.0 40.3 75.0 120.2 74.4 69.3 80.3 130.2 67.7 46.8 32.2 65.2 50.1 53.2 87.9 5.9 99.6 71.2 36.7 43.9 146.2 86.4 29.2 125.8 40.4 37.9 34.3 31.8 166.5 35.6 17.9 21.8 56.6 26.0 92.1 35.1 77.1 91.9 12.1 13.0 12.5 14.8 12.5 14.8 14.3 12.9 15.4 12.4 13.5 15.1 8.7 19.2 25.3 39.2 18.6 6.0 13.6 60.1 10.8 11.3 11.5 7.5 9.1 34.3 43.3 27.6 6.2 100.1 14.1 41.9 27.4 53.5 24.8 18.7 16.0 17.4 16.9 20.6 46.7 35.4 55.3 29.2 26.0 27.1 26.6 20.6 19.6 39.7 79.5 5.0 46.0 23.5 40.7 43.9 13.9 5.0 15.2 41.7 14.2 23.4 64.6 16.5 10.3 27.2 24.2 28.1 43.4 21.1 19.8 9.9 36.2 33.1 31.0 16.2 13.1 12.9 16.3 1.0 6.6 10.1 3.4 49.1 18.7 51.0 32.0 12.1 GPR141 PGR13 ENSG00000187037 "G protein-coupled receptor 141" Q7Z602 7 37683796-37833788 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 27.9" "Cell type enhanced" "Detected in some" "dendritic cells: 8.9;granulocytes: 23.4;Langerhans cells: 8.2;monocytes: 7.5;NK-cells: 13.4;Oligodendrocytes: 14.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "classical monocyte: 13.0;eosinophil: 9.7;gdT-cell: 5.2;memory CD8 T-cell: 5.1;myeloid DC: 6.6;naive CD8 T-cell: 3.4;neutrophil: 12.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 13.2;HMC-1: 49.7;NB-4: 8.0;NTERA-2: 27.1;THP-1: 8.2;U-937: 21.9" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (4.91e-2)" "unprognostic (3.44e-1)" "unprognostic (3.26e-4)" "unprognostic (4.70e-3)" "unprognostic (8.67e-2)" "unprognostic (2.00e-2)" "unprognostic (3.01e-1)" "unprognostic (2.51e-2)" "unprognostic (7.93e-3)" "unprognostic (1.44e-1)" "unprognostic (1.51e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-3)" "unprognostic (1.39e-2)" "unprognostic (4.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.60e-1)" 1.4 0.4 0.6 4.1 1.5 27.9 0.6 1.2 0.7 1.3 0.9 1.2 0.8 0.7 0.4 1.5 0.5 2.2 0.3 0.3 1.3 0.3 0.7 1.8 1.9 3.2 1.2 0.1 0.2 0.3 0.1 2.4 1.9 0.4 1.7 0.0 0.3 0.3 0.2 0.9 1.2 1.5 1.5 3.0 0.8 0.8 1.8 1.4 0.3 0.6 1.8 3.7 0.2 3.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 13.2 1.0 0.0 0.0 0.3 49.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 8.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 21.9 0.0 0.0 13.0 9.7 5.2 0.9 0.0 0.0 1.2 5.1 6.6 0.0 0.5 3.4 12.3 0.8 0.1 0.2 0.0 4.3 0.6 1.5 1.2 0.7 0.3 1.3 3.2 1.2 1.9 1.5 1.8 3.0 0.0 3.2 3.0 0.3 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 8.9 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.1 0.0 0.1 23.4 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 5.4 8.2 1.3 0.0 5.7 0.0 1.9 7.5 0.0 13.4 1.0 14.4 0.0 0.0 0.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.6 0.0 0.1 0.3 2.3 0.0 0.0 0.0 GPX1 ENSG00000233276 "Glutathione peroxidase 1" P07203 3 49357176-49358353 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3273.8;Kupffer cells: 3971.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1534.3;granulocytes: 1010.7;monocytes: 1337.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011582, HPA044758" Approved Supported Cytosol NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB011582: AB_2112120, HPA044758: AB_2679076" "unprognostic (1.50e-2)" "unprognostic (4.34e-3)" "unprognostic (1.25e-1)" "prognostic favorable (7.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (6.73e-3)" "unprognostic (5.03e-2)" "unprognostic (3.40e-2)" "unprognostic (2.48e-1)" "unprognostic (5.46e-2)" "unprognostic (1.53e-1)" "unprognostic (7.64e-3)" "unprognostic (9.14e-3)" "unprognostic (3.16e-2)" "unprognostic (5.72e-3)" "unprognostic (7.64e-3)" 321.4 200.0 178.3 151.9 186.6 246.7 151.5 190.2 298.9 90.9 247.3 86.9 122.2 82.2 17.8 134.3 86.5 91.1 95.5 173.1 198.9 152.9 281.6 168.3 174.3 234.0 213.0 61.9 74.4 35.2 85.7 121.2 208.3 107.0 42.7 8.3 113.1 53.9 157.1 70.4 113.6 70.4 218.0 195.9 92.9 31.5 217.6 75.3 82.1 61.7 86.6 116.8 94.9 256.3 322.8 189.2 72.6 95.4 113.5 205.9 225.9 217.7 114.7 151.5 80.1 157.8 229.7 0.6 301.6 139.8 181.7 93.2 98.8 660.3 31.6 200.2 271.6 224.8 190.2 397.4 575.6 161.0 594.4 455.9 267.6 292.4 221.5 190.0 341.5 78.6 0.5 179.3 125.9 0.8 51.2 407.0 441.3 147.4 510.5 190.8 93.8 120.3 258.2 385.6 87.7 178.5 249.5 1.5 287.3 75.7 1.5 559.5 546.5 209.7 236.0 385.8 453.6 1.1 127.9 116.3 390.5 436.3 507.8 1010.7 1337.0 707.6 69.8 483.7 100.9 314.2 127.7 83.7 1093.1 276.8 118.4 116.2 136.4 107.4 275.8 1534.3 233.3 1401.2 178.3 186.6 190.2 298.9 173.1 198.9 234.0 213.0 208.3 218.0 217.6 256.3 0.0 109.0 323.5 6.2 148.1 249.7 432.8 985.0 92.2 32.1 0.0 0.0 0.0 220.2 616.7 0.0 10.4 499.9 491.5 229.5 0.0 0.0 300.7 0.0 0.0 227.8 251.3 364.1 12.8 0.0 830.3 131.0 73.4 0.0 480.6 0.0 585.7 888.1 3273.8 1.7 17.9 285.0 386.6 3971.6 965.7 1102.9 134.5 1305.5 273.9 41.2 828.6 63.4 138.0 8.0 7.6 0.0 179.0 67.0 82.4 481.0 349.9 0.0 490.0 14.6 210.4 150.6 151.8 12.7 169.4 112.1 154.1 278.8 112.2 0.0 367.3 517.0 GRN "CLN11, PCDGF, PGRN" ENSG00000030582 "Granulin precursor" P28799 17 44345246-44353106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 1420.7;Kupffer cells: 892.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 2057.5;intermediate monocyte: 1122.4;myeloid DC: 1534.2;neutrophil: 851.2;non-classical monocyte: 548.1;plasmacytoid DC: 1331.9" "Group enriched" "Detected in all" 9 "dendritic cells: 1534.2;granulocytes: 851.2;monocytes: 2057.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008763, CAB019394, HPA028747" Uncertain Enhanced Endosomes,Lysosomes "Secreted to blood" NA NA 138000000 110000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Lysosomes Endosomes "CAB019394: , HPA008763: AB_1850339, HPA028747: AB_10603767" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "unprognostic (8.38e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (7.41e-2)" "unprognostic (3.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.52e-1)" "unprognostic (6.34e-2)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" 158.9 123.2 61.5 160.4 67.2 478.5 120.7 67.7 97.3 156.7 73.9 189.8 130.9 108.3 134.0 534.0 87.1 157.3 153.0 61.0 69.7 167.4 118.9 309.5 183.2 81.0 71.5 73.8 108.9 87.8 84.4 183.2 87.6 111.7 110.3 12.5 262.9 100.6 60.6 189.7 179.0 91.9 71.8 349.8 127.9 59.4 94.3 67.8 127.7 45.9 107.8 150.0 198.3 97.3 119.3 197.5 52.7 159.5 443.2 231.8 181.2 147.3 447.5 231.6 309.8 86.3 294.0 364.0 299.4 217.6 312.9 185.3 68.6 334.5 75.8 55.8 186.8 38.4 93.8 175.2 245.5 61.6 493.6 332.4 450.5 188.1 106.0 391.2 269.8 64.3 75.1 51.3 148.8 183.1 32.8 172.8 44.3 110.5 334.0 97.7 180.8 433.0 248.2 145.9 54.7 74.7 201.0 92.7 360.9 138.0 209.4 229.0 340.7 437.6 104.6 300.5 97.8 116.3 313.9 122.3 268.1 149.6 124.2 215.1 2057.5 176.5 35.1 1122.4 27.8 174.0 37.1 31.1 1534.2 112.2 27.8 26.5 851.2 30.6 548.1 1331.9 55.4 1613.4 61.5 67.2 67.7 97.3 61.0 69.7 81.0 71.5 87.6 71.8 94.3 97.3 113.0 86.6 83.3 12.7 82.8 112.7 151.1 574.2 97.9 23.6 85.7 69.7 90.7 133.0 332.7 218.8 18.8 429.1 195.7 494.8 9.8 447.7 2.1 103.8 83.8 170.9 124.3 38.7 6.8 307.3 324.1 149.4 83.6 372.5 75.5 90.0 207.8 84.7 1420.7 47.1 6.6 214.6 146.5 892.0 360.8 6.8 60.9 699.2 208.1 20.6 501.6 58.9 20.6 11.1 11.8 285.3 581.7 57.2 65.8 70.7 312.1 120.5 70.0 11.8 85.5 45.4 83.3 25.1 72.2 255.5 96.5 640.0 30.8 89.6 274.5 175.6 GSTO1 "GSTTLp28, P28" ENSG00000148834 "Glutathione S-transferase omega 1" P78417 10 104235356-104267459 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 657.7" "Cell type enhanced" "Detected in all" "Hofbauer cells: 676.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 1106.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037603, HPA037604" Enhanced NA NA 120000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 51: Myeloid cells - Hemostasis" "HPA037603: AB_2675574, HPA037604: AB_10672283" "prognostic favorable (6.95e-4)" "unprognostic (9.23e-2)" "unprognostic (1.43e-2)" "unprognostic (6.83e-2)" "unprognostic (7.16e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (9.23e-3)" "unprognostic (4.57e-2)" "unprognostic (7.65e-2)" "unprognostic (2.13e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.86e-2)" "unprognostic (1.29e-1)" "unprognostic (5.51e-3)" "unprognostic (5.82e-2)" 95.0 145.4 119.1 102.8 123.1 191.6 89.9 121.3 166.7 90.1 118.0 92.7 167.6 72.0 96.2 79.3 75.4 84.8 277.4 117.3 124.8 154.4 657.7 154.7 93.1 121.3 127.1 83.1 80.5 129.7 102.9 113.6 122.7 80.3 94.8 38.2 75.6 89.6 148.4 63.8 165.2 86.9 122.2 107.1 93.3 14.9 128.8 124.8 82.9 122.5 77.4 109.6 82.6 136.4 287.7 194.5 142.9 249.3 201.4 385.1 62.8 358.3 640.7 237.9 257.2 247.2 292.8 254.2 152.8 245.6 296.8 158.8 97.0 329.2 244.5 128.4 233.7 186.6 122.1 542.7 359.7 241.5 294.5 291.5 136.7 346.3 414.5 331.3 464.1 231.2 394.4 153.4 511.4 159.3 188.3 330.0 130.4 308.1 134.8 136.0 94.9 108.1 358.4 185.1 72.1 88.6 117.6 81.0 1106.0 238.2 92.0 192.7 426.6 276.9 143.6 427.3 328.4 2.7 3.3 2.0 517.7 416.2 112.0 842.8 532.4 157.9 133.0 457.0 164.5 148.8 164.6 172.9 429.3 111.9 143.0 144.3 151.8 185.0 369.1 203.0 204.8 632.1 119.1 123.1 121.3 166.7 117.3 124.8 121.3 127.1 122.7 122.2 128.8 136.4 107.4 76.9 72.6 8.8 64.8 93.7 328.2 297.6 51.2 36.9 63.5 105.5 328.2 218.8 113.3 101.2 20.9 394.2 82.0 101.6 332.6 341.0 22.4 68.1 79.6 164.5 103.5 192.8 12.1 248.4 176.6 173.0 49.5 81.7 146.3 107.6 388.0 628.2 676.5 23.5 11.7 163.8 124.1 321.8 223.6 17.3 114.6 484.5 126.3 8.4 277.7 81.2 95.8 8.5 21.8 347.6 150.7 112.8 39.9 169.4 483.2 538.0 114.3 29.8 151.2 85.3 176.1 5.7 5.1 55.8 78.7 111.0 81.4 224.8 196.6 204.9 GSTP1 "FAEES3, GST3, GSTP" ENSG00000084207 "Glutathione S-transferase pi 1" P09211 11 67583742-67586656 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2087.9" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 4033.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 4998.3;OE19: 7810.3" "Low region specificity" "Detected in all" "HPA019779, HPA019869" Enhanced Supported Mitochondria,Cytosol No No 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Mitochondria, Cytosol" "HPA019779: AB_1849799, HPA019869: AB_1849801" "unprognostic (9.81e-2)" "unprognostic (6.52e-2)" "unprognostic (7.24e-2)" "unprognostic (2.72e-2)" "unprognostic (1.06e-2)" "unprognostic (1.30e-3)" "unprognostic (3.27e-1)" "unprognostic (4.98e-2)" "unprognostic (1.28e-1)" "unprognostic (5.16e-3)" "unprognostic (2.14e-3)" "unprognostic (9.37e-2)" "unprognostic (5.72e-2)" "unprognostic (7.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.72e-3)" "unprognostic (1.48e-1)" 290.5 276.2 346.8 232.1 370.3 601.3 288.7 358.9 425.7 641.9 695.8 329.6 394.6 331.9 280.3 2087.9 647.5 435.8 367.2 341.4 381.9 567.7 45.1 468.3 321.8 375.7 379.2 306.9 340.9 737.4 320.2 326.9 378.5 291.7 197.1 137.9 541.2 780.4 355.0 731.4 321.7 214.2 367.0 257.2 535.5 45.8 378.1 296.9 579.0 312.5 380.8 526.5 946.2 377.7 1202.5 1599.4 763.7 1198.9 577.8 645.2 705.3 511.3 678.1 761.2 589.3 2956.3 1225.0 3.3 1144.7 813.5 683.7 1707.8 2073.9 2248.5 214.4 848.0 765.3 59.9 1107.6 0.5 852.2 400.3 667.6 807.2 4998.3 609.9 583.3 560.9 1160.2 847.2 1318.2 321.8 605.7 4.3 918.2 1100.6 1475.2 7810.3 681.3 844.8 129.6 3.8 1236.8 3.6 260.6 754.3 719.1 230.9 2394.0 598.2 3.6 656.3 634.5 351.6 883.8 740.6 378.6 200.0 1353.9 447.1 400.0 652.4 747.8 56.0 3145.4 246.6 720.0 2470.8 271.9 509.2 322.4 597.7 3582.7 476.3 267.8 466.5 130.5 1443.8 1608.5 1435.1 363.3 3948.4 346.8 370.3 358.9 425.7 341.4 381.9 375.7 379.2 378.5 367.0 378.1 377.7 466.7 1153.8 872.3 25.5 296.8 865.6 1914.8 3813.8 767.2 170.0 628.7 838.3 297.3 987.9 2763.5 1230.4 33.3 2116.8 372.4 655.0 1805.9 1811.9 4.9 1381.0 589.0 431.4 368.2 166.3 6.8 1444.4 1703.9 710.5 781.9 1020.9 269.9 795.0 382.3 10.5 861.2 70.7 10.1 992.4 1930.7 597.9 1090.3 25.5 572.3 703.5 1531.5 27.2 2166.5 558.5 459.3 17.6 38.4 1412.1 948.9 400.2 591.6 2266.2 844.4 3495.5 3715.4 274.4 361.6 401.3 941.7 4.8 54.9 4033.7 1061.7 1645.5 342.5 527.8 1118.5 3418.6 H2AJ "FLJ10903, H2AFJ, MGC921" ENSG00000246705 "H2A.J histone" Q9BTM1 12 14774383-14778002 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 565.0" "Cell type enhanced" "Detected in some" "Adipocytes: 58.1;Cytotrophoblasts: 130.2;dendritic cells: 56.4;Extravillous trophoblasts: 124.3;Fibroblasts: 59.5;Hofbauer cells: 241.2;Syncytiotrophoblasts: 160.3" "Cancer enhanced" "Detected in all" "prostate cancer: 151.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 256.2;MCF7: 338.4;RT4: 239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (9.38e-2)" "unprognostic (8.49e-2)" "unprognostic (9.15e-2)" "unprognostic (7.06e-2)" "unprognostic (2.43e-3)" "unprognostic (4.70e-2)" "unprognostic (3.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.16e-1)" "unprognostic (1.14e-1)" "unprognostic (5.37e-2)" "unprognostic (4.05e-2)" "unprognostic (3.32e-3)" "unprognostic (3.43e-2)" "unprognostic (8.66e-3)" "unprognostic (5.22e-3)" "unprognostic (3.87e-3)" 236.7 186.0 29.1 33.8 34.1 60.4 223.6 33.7 40.9 123.7 37.9 126.6 55.4 105.6 20.9 155.7 106.6 36.0 125.5 27.7 31.3 115.7 82.7 129.6 29.6 37.1 32.5 63.6 182.3 21.1 34.2 57.7 35.7 275.8 29.3 5.3 166.8 35.0 91.4 198.4 85.2 25.1 33.4 94.8 111.1 565.0 33.1 34.2 85.0 24.8 18.2 122.8 124.9 38.7 107.9 256.2 10.0 0.0 112.2 73.8 163.2 78.9 43.4 31.3 30.4 50.9 172.4 0.1 48.7 38.6 0.2 100.7 6.2 60.1 8.5 5.7 4.6 4.3 92.6 43.8 160.5 0.1 39.0 97.0 64.5 43.3 40.0 12.7 63.0 0.0 0.1 0.1 15.9 338.4 0.7 28.7 16.0 77.8 58.0 42.4 0.0 21.0 51.0 239.0 3.0 1.0 99.8 122.3 0.4 34.6 187.0 32.6 63.1 0.3 29.6 46.2 15.6 25.0 39.4 0.4 8.6 0.3 25.4 84.0 127.6 29.3 51.3 76.4 46.3 16.8 49.6 38.0 117.2 21.7 34.9 38.2 46.6 61.2 69.4 58.2 78.1 72.1 29.1 34.1 33.7 40.9 27.7 31.3 37.1 32.5 35.7 33.4 33.1 38.7 58.1 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 0.0 0.0 0.0 0.0 130.2 56.4 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 124.3 59.5 0.0 0.0 0.0 0.0 0.0 0.0 241.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 0.0 0.0 160.3 6.5 0.0 0.0 0.0 HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 502.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 470000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" 105.0 125.3 57.7 31.1 60.7 46.3 94.9 65.0 69.6 72.6 59.1 108.4 115.0 61.8 30.7 90.1 60.1 32.4 330.2 52.8 61.9 99.0 156.7 66.9 35.3 64.4 62.2 77.8 101.4 95.0 57.4 39.2 64.2 60.2 76.1 14.9 77.9 33.4 502.5 95.7 106.2 57.4 61.8 68.4 93.8 49.0 62.4 46.7 59.5 300.7 58.5 79.1 73.6 67.2 105.7 88.1 58.4 90.8 221.1 139.9 51.5 80.6 84.7 78.5 67.7 114.7 104.1 71.7 50.2 138.4 78.6 66.8 103.4 152.6 72.5 139.1 103.6 103.3 86.2 197.9 73.3 132.2 69.2 142.7 101.6 112.4 109.3 82.8 127.7 70.4 140.2 133.2 101.1 128.2 63.4 137.7 50.1 77.5 134.1 52.9 128.5 143.7 90.3 125.3 41.9 85.1 94.6 104.6 102.4 44.5 52.2 125.8 127.1 48.8 70.7 69.9 58.0 44.8 86.5 113.4 77.6 150.2 56.2 22.5 84.0 33.5 31.8 92.3 39.1 40.5 36.8 38.7 80.8 31.2 42.6 40.1 20.9 38.8 86.1 31.3 50.9 89.9 57.7 60.7 65.0 69.6 52.8 61.9 64.4 62.2 64.2 61.8 62.4 67.2 122.4 89.8 99.0 47.0 101.2 89.0 137.5 139.9 97.3 35.6 89.7 96.4 349.9 82.9 128.0 77.3 52.1 182.0 95.1 242.1 131.0 120.8 39.2 73.3 121.1 99.1 91.4 155.9 22.8 108.5 94.7 96.1 100.4 85.5 139.9 140.3 84.3 185.1 163.0 20.2 28.2 156.5 89.5 136.8 106.0 74.3 92.6 145.0 81.8 12.2 170.7 65.4 93.7 30.7 37.4 90.0 195.6 84.2 90.4 76.2 527.4 182.5 84.8 62.3 52.6 129.9 109.6 147.9 54.9 136.5 103.3 129.2 100.5 154.7 216.7 104.4 HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290465 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 793.3;skeletal muscle: 950.6;tongue: 1097.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1167.5;Distal tubular cells: 520.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037539, HPA037540, HPA066099" Enhanced Supported Mitochondria No No 61000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA037539: AB_10671374, HPA037540: AB_2675531, HPA066099: AB_2685618" "unprognostic (5.15e-2)" "unprognostic (8.72e-2)" "unprognostic (8.21e-2)" "unprognostic (8.67e-2)" "unprognostic (7.70e-2)" "unprognostic (2.59e-2)" "unprognostic (7.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (2.03e-1)" "unprognostic (8.94e-2)" "prognostic favorable (1.37e-9)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (2.88e-1)" "unprognostic (9.68e-2)" 127.0 224.7 120.6 51.1 135.4 58.8 91.3 146.4 138.1 65.2 128.0 110.7 224.2 55.9 73.7 101.3 68.8 64.3 793.3 109.0 138.1 231.4 324.8 64.7 54.9 135.9 141.6 78.4 83.7 209.5 48.1 65.6 139.6 77.1 113.2 63.0 104.8 75.0 950.6 74.4 184.4 79.0 141.4 75.8 109.0 67.1 143.3 53.1 90.8 1097.1 62.5 89.2 64.1 152.8 108.2 83.2 56.6 102.2 342.1 190.1 57.9 89.0 134.6 89.0 86.8 100.5 101.7 53.9 60.8 145.3 100.1 82.8 95.2 124.8 109.2 121.1 83.1 123.6 44.9 194.2 145.9 100.6 90.0 183.7 201.6 92.7 149.0 151.0 168.2 81.0 105.2 83.9 189.5 78.0 57.1 190.7 39.8 160.2 89.0 61.7 188.3 103.2 183.3 148.9 27.2 93.7 151.7 169.8 239.5 68.5 105.4 177.9 118.0 83.5 86.9 79.3 65.1 62.6 101.1 94.7 95.5 158.4 84.4 95.7 168.1 66.4 45.2 150.3 57.6 65.5 61.3 56.6 154.2 49.7 55.8 51.3 72.7 88.2 123.3 51.8 94.7 135.6 120.6 135.4 146.4 138.1 109.0 138.1 135.9 141.6 139.6 141.4 143.3 152.8 106.5 48.1 36.5 63.0 48.3 62.1 136.5 183.3 49.5 29.3 49.5 52.3 1167.5 104.4 107.7 97.5 56.3 227.9 42.4 129.5 520.4 124.0 93.4 59.5 49.0 75.2 74.9 85.2 32.7 57.2 75.2 79.5 53.0 60.2 62.8 94.2 69.9 277.6 139.6 13.5 33.0 93.4 114.0 98.1 67.4 99.7 56.5 78.1 88.9 27.2 110.2 65.0 32.0 35.2 47.5 58.4 134.8 62.8 37.1 60.5 376.0 321.1 73.5 80.0 72.3 72.9 80.7 120.4 49.4 53.8 54.7 186.6 45.2 194.0 113.5 110.3 HDHD5 CECR5 ENSG00000069998 "Haloacid dehalogenase like hydrolase domain containing 5" Q9BXW7 22 17137511-17165287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 43.0;Ductal cells: 35.2;Extravillous trophoblasts: 42.2;Granulosa cells: 37.0;Hofbauer cells: 42.3;Proximal tubular cells: 41.1;Theca cells: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005548 Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA005548: AB_1078497" "unprognostic (4.04e-2)" "unprognostic (5.04e-2)" "unprognostic (4.54e-3)" "unprognostic (6.61e-2)" "unprognostic (1.20e-1)" "unprognostic (5.71e-2)" "unprognostic (1.04e-3)" "unprognostic (7.35e-2)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (5.76e-2)" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (7.07e-3)" "unprognostic (1.71e-1)" "unprognostic (1.20e-2)" "unprognostic (7.21e-3)" 17.4 29.7 15.0 13.2 15.3 16.5 17.3 15.4 15.7 12.9 16.7 21.5 26.5 14.6 6.8 21.7 13.6 9.8 45.0 15.4 14.8 19.8 40.5 12.6 14.5 15.4 14.9 12.2 20.9 17.5 11.6 8.1 14.6 15.5 14.1 5.7 18.6 10.0 46.9 23.0 17.2 11.4 14.8 19.3 19.9 15.9 15.9 13.6 10.1 55.7 12.0 16.5 14.1 15.0 64.0 41.5 30.5 41.5 17.7 10.8 38.8 17.9 19.6 47.1 50.2 61.1 23.3 103.9 29.3 21.6 23.0 44.0 38.7 42.0 21.8 31.6 56.7 0.0 30.7 0.0 29.4 47.6 23.5 26.1 51.1 21.0 23.1 26.4 33.3 67.4 31.0 26.2 24.9 62.1 84.2 97.2 46.6 97.9 36.7 47.4 45.8 26.3 32.2 34.7 61.4 46.5 34.9 49.9 54.3 23.9 50.1 58.5 29.1 39.7 29.4 28.2 31.3 41.3 48.5 77.8 32.0 0.1 34.2 12.3 86.2 4.7 28.4 56.7 35.6 24.6 26.4 25.8 74.5 23.6 34.3 29.3 4.5 30.7 31.4 30.9 29.7 48.0 15.0 15.3 15.4 15.7 15.4 14.8 15.4 14.9 14.6 14.8 15.9 15.0 21.5 6.4 2.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 23.9 22.4 0.0 0.0 5.0 5.5 0.0 26.5 9.3 0.0 43.0 35.2 0.0 8.4 14.9 9.2 0.0 0.0 0.0 28.2 42.2 7.7 0.0 11.5 5.1 37.0 0.0 0.0 42.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 5.2 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.5 0.0 0.0 41.1 1.5 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 15.7 3.4 55.8 0.0 0.0 HEXB ENSG00000049860 "Hexosaminidase subunit beta" P07686 5 74640023-74722647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 466.5;Hofbauer cells: 340.2;Syncytiotrophoblasts: 493.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 746.0;GAMG: 646.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055409, HPA056010" Enhanced "Intracellular and membrane" NA NA 40000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA055409: AB_2682808, HPA056010: AB_2683008" "unprognostic (3.45e-1)" "unprognostic (5.84e-2)" "unprognostic (1.85e-2)" "unprognostic (8.72e-2)" "unprognostic (1.12e-2)" "unprognostic (6.44e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (2.21e-1)" "unprognostic (5.01e-2)" "unprognostic (1.58e-3)" "unprognostic (6.45e-2)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (1.31e-2)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" 92.2 72.0 22.1 59.7 25.3 59.9 83.0 22.3 32.5 97.6 39.4 105.0 99.0 71.5 321.4 38.5 66.7 99.0 84.3 23.1 26.2 81.6 137.5 111.3 47.0 23.8 22.9 62.4 103.6 94.2 46.6 319.4 24.7 98.7 116.9 33.6 123.4 54.0 43.3 54.3 75.4 76.1 23.2 64.7 88.4 19.6 28.2 29.1 89.6 38.4 40.4 94.6 64.1 30.4 147.3 111.0 39.4 131.8 746.0 232.3 122.3 173.5 590.4 175.0 375.2 130.6 194.5 0.0 133.0 152.2 646.3 115.2 43.2 185.2 228.7 79.2 72.6 19.1 101.4 101.5 216.5 16.2 152.3 206.7 108.0 180.7 121.3 275.9 204.5 47.3 54.3 236.9 194.9 145.7 19.8 36.6 36.8 142.7 47.8 43.9 56.2 191.8 119.8 130.4 24.5 30.4 134.2 92.6 180.0 68.8 99.1 108.6 118.5 112.1 26.6 207.8 165.6 102.6 191.3 0.9 257.9 143.6 209.8 86.2 343.2 99.1 69.3 129.9 80.7 45.2 56.1 64.0 310.8 28.1 52.6 51.3 125.2 42.4 82.5 93.4 73.2 269.0 22.1 25.3 22.3 32.5 23.1 26.2 23.8 22.9 24.7 23.2 28.2 30.4 49.6 41.7 38.4 5.9 31.5 44.0 82.8 103.2 21.6 10.2 26.3 27.6 19.8 82.9 63.8 29.5 8.4 466.5 32.8 68.2 19.6 151.3 1.3 21.0 21.4 56.2 22.8 23.1 32.2 125.6 175.4 107.2 33.6 26.9 69.8 19.8 74.3 70.1 340.2 10.1 24.3 56.7 107.8 127.3 134.3 3.4 85.1 168.8 72.9 17.8 114.2 35.4 29.9 22.6 13.3 65.8 54.8 72.2 71.5 74.2 99.5 79.6 36.3 16.3 46.0 32.6 49.5 0.3 1.4 23.8 32.5 493.6 35.3 31.4 81.8 71.0 HLA-C "D6S204, HLA-JY3, PSORS1" ENSG00000204525 "Major histocompatibility complex, class I, C" P10321 6 31268749-31272130 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1445.7" "Cell type enhanced" "Detected in all" "NK-cells: 3899.1;Proximal enterocytes: 3582.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 760.0;EFO-21: 795.5;RPTEC TERT1: 462.7;U-266/70: 481.6;U-266/84: 401.0;U-698: 289.3" "Intracellular and membrane" NA NA 240000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.17e-1)" "unprognostic (3.38e-1)" "unprognostic (3.05e-2)" "unprognostic (4.42e-2)" "unprognostic (1.56e-1)" "unprognostic (2.08e-1)" "unprognostic (1.51e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-3)" "unprognostic (3.23e-3)" "unprognostic (1.17e-1)" "unprognostic (2.39e-1)" "unprognostic (2.34e-1)" "unprognostic (2.00e-1)" "unprognostic (8.12e-2)" "unprognostic (1.87e-2)" "unprognostic (7.16e-2)" 538.6 417.5 0.7 274.6 2.4 122.3 507.4 0.8 0.9 464.4 1.5 594.3 1.6 434.8 259.5 277.6 411.7 103.9 424.3 0.3 1.1 561.0 485.7 1078.3 334.0 1.6 0.9 266.3 245.3 0.2 269.6 34.5 0.9 344.2 27.7 13.7 389.5 0.4 190.6 449.6 750.0 51.0 1.3 1445.7 419.4 62.3 1.2 2.4 382.9 0.3 0.7 372.7 377.5 0.8 760.0 1.1 0.0 0.0 120.1 94.1 1.7 3.1 0.9 1.1 2.3 0.9 0.0 0.4 795.5 190.8 208.7 0.5 0.0 188.1 0.0 1.4 170.4 0.8 8.1 0.1 0.8 0.5 0.5 80.5 0.2 0.5 0.0 272.4 0.0 92.5 0.4 0.0 0.0 0.0 7.8 4.8 0.5 0.0 0.8 1.9 0.3 1.9 462.7 0.0 0.9 1.5 0.2 0.1 2.2 0.3 0.3 3.3 0.6 196.4 65.8 2.3 2.5 481.6 401.0 289.3 0.3 8.2 0.2 1.9 2.8 2.3 0.7 0.8 0.6 0.4 0.4 0.6 0.4 0.4 0.4 0.5 2.8 0.8 0.3 0.1 0.9 46.1 0.7 2.4 0.8 0.9 0.3 1.1 1.6 0.9 0.9 1.3 1.2 0.8 1903.4 227.6 328.1 13.1 1576.5 729.1 757.8 1082.3 236.8 33.4 457.0 342.8 61.2 807.8 662.7 483.7 10.4 39.5 2429.1 1994.0 84.1 1966.4 25.6 233.7 343.8 1466.2 482.2 301.2 3.9 1511.3 1010.7 608.5 648.8 557.2 344.1 256.3 1390.0 469.2 1579.0 99.3 5.8 1375.7 923.7 2050.7 1492.7 32.1 507.3 1595.9 836.0 76.8 2570.1 207.3 3899.1 18.6 3.8 1272.7 2195.7 333.6 2482.6 1038.0 3582.3 232.5 548.5 24.0 1203.0 336.7 558.8 142.0 43.5 192.6 651.7 121.6 2212.1 786.8 1003.1 1160.6 HNMT ENSG00000150540 "Histamine N-methyltransferase" P50135 2 137964020-138016364 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 245.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 299.3;Kupffer cells: 263.7;Proximal tubular cells: 268.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 21 "classical monocyte: 110.9;intermediate monocyte: 89.8;myeloid DC: 68.3;non-classical monocyte: 52.2" "Group enriched" "Detected in many" 23 "dendritic cells: 68.3;monocytes: 110.9" "Cell line enhanced" "Detected in many" "Hep G2: 227.2;HSkMC: 87.9;RT4: 117.1;SuSa: 107.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035480, HPA035481, HPA073754" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA 130000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" Centrosome "HPA035480: AB_2674645, HPA035481: AB_10672094, HPA073754: " "unprognostic (1.32e-1)" "unprognostic (3.53e-1)" "unprognostic (5.44e-2)" "unprognostic (2.09e-2)" "unprognostic (2.81e-1)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.02e-2)" "unprognostic (5.69e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.41e-4)" "unprognostic (5.24e-2)" "unprognostic (1.34e-2)" "unprognostic (1.76e-2)" "unprognostic (5.34e-2)" "unprognostic (1.21e-1)" "prognostic favorable (4.68e-4)" 70.4 18.2 13.0 41.7 13.3 12.6 62.3 13.1 18.8 57.3 19.2 53.9 29.3 62.8 27.1 17.5 34.5 68.7 21.7 15.6 19.1 109.7 245.9 49.0 35.1 16.0 15.3 91.0 29.0 40.2 9.5 46.8 18.1 37.0 56.4 6.1 30.5 44.3 5.9 17.4 29.1 33.1 16.1 37.5 29.1 10.3 14.5 8.2 14.6 11.9 16.4 49.7 24.5 22.2 0.7 0.9 5.6 14.6 61.9 64.6 0.4 3.9 6.2 0.4 2.3 29.7 15.7 0.9 50.2 17.0 0.8 1.1 11.9 0.0 0.1 0.7 4.9 0.2 44.5 227.2 28.0 0.3 0.6 87.9 0.1 21.5 0.0 4.7 15.9 0.1 0.5 0.7 47.4 3.7 0.0 0.5 28.1 39.3 5.6 0.5 1.5 0.2 67.9 117.1 0.1 0.8 22.1 28.4 0.1 107.9 1.0 53.2 4.8 4.8 11.8 6.2 16.3 0.4 0.3 0.7 20.9 27.8 3.3 1.3 110.9 0.7 0.5 89.8 0.3 1.8 0.2 0.2 68.3 0.5 0.3 0.4 3.9 0.5 52.2 1.5 0.7 32.6 13.0 13.3 13.1 18.8 15.6 19.1 16.0 15.3 18.1 16.1 14.5 22.2 15.5 28.9 44.1 9.4 5.0 35.6 81.5 64.6 30.7 0.7 78.1 65.4 2.2 133.0 88.9 60.7 0.0 54.9 2.6 59.4 123.3 122.1 1.5 28.3 50.6 9.4 16.4 16.8 16.8 48.0 81.6 54.2 20.9 115.3 0.0 17.4 19.2 165.7 299.3 0.0 13.8 67.8 24.4 263.7 97.2 4.2 131.4 127.4 56.9 31.9 122.0 25.5 4.1 45.8 14.3 71.0 108.6 105.3 0.2 39.8 31.9 268.3 38.4 0.8 78.9 55.2 55.7 0.5 0.9 33.2 25.9 37.6 4.0 43.9 83.5 126.1 HOMER3 HOMER-3 ENSG00000051128 "Homer scaffold protein 3" Q9NSC5 19 18929201-18941261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 125.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 76.4;Muller glia cells: 72.6;Proximal tubular cells: 84.2;Theca cells: 322.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 15.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 353.6;THP-1: 420.0;U-266/84: 375.4" "Region enriched" "Detected in all" 6 "cerebellum: 189.2" "Low region specificity" "Detected in all" "CAB032656, HPA040999, CAB079015" Enhanced Supported Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane, Cytoplasmic bodies" "CAB032656: AB_2120801, CAB079015: , HPA040999: AB_2677242" "unprognostic (3.41e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.24e-5)" "unprognostic (1.19e-1)" "unprognostic (2.06e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.07e-1)" "unprognostic (8.88e-2)" "unprognostic (5.78e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (5.99e-2)" "unprognostic (3.76e-2)" "unprognostic (2.33e-1)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" 33.1 29.6 33.3 9.9 41.9 22.3 26.2 76.9 44.6 31.7 41.1 27.0 7.0 24.6 6.4 15.3 16.7 16.5 25.0 40.4 35.1 52.2 6.1 25.6 7.9 42.3 40.9 20.1 12.4 37.5 8.6 14.7 42.8 21.9 6.0 5.9 27.6 9.4 114.5 35.4 14.4 10.6 39.4 125.1 17.0 9.2 41.6 7.4 49.3 18.6 3.8 29.7 26.0 45.5 112.1 28.5 53.1 44.4 48.3 48.6 26.2 108.1 94.9 106.4 53.4 14.6 41.8 0.9 49.9 122.1 76.1 68.6 18.4 140.4 58.9 4.0 11.0 0.1 9.7 27.5 44.9 21.5 1.7 39.3 89.4 59.0 79.1 113.0 130.3 7.9 3.2 28.6 78.1 30.3 1.9 353.6 27.3 6.1 115.5 55.2 16.2 53.4 38.2 28.3 0.2 44.8 26.6 31.2 78.5 10.2 14.0 420.0 105.3 94.0 42.0 114.5 132.2 274.2 375.4 93.6 148.0 270.6 69.8 0.1 15.0 2.9 0.1 5.3 0.0 2.3 0.8 0.3 1.3 2.7 0.1 0.0 5.8 0.0 1.6 0.2 0.8 4.2 33.3 41.9 76.9 44.6 40.4 35.1 42.3 40.9 42.8 39.4 41.6 45.5 21.7 3.2 0.0 9.4 9.3 11.9 22.4 24.4 6.8 2.2 14.3 22.5 4.1 2.8 8.0 12.9 0.0 1.0 0.6 0.1 11.7 22.9 2.0 4.3 18.7 38.0 1.8 0.4 0.3 13.6 2.4 20.5 0.0 6.3 10.2 34.8 21.8 0.7 76.4 1.7 3.9 0.9 22.4 16.2 7.6 1.7 13.7 32.2 12.4 1.9 8.3 72.6 0.0 1.0 13.4 42.0 0.0 10.9 13.8 25.2 0.0 84.2 3.6 4.1 0.0 14.4 27.8 4.7 6.7 4.2 14.5 1.1 2.5 322.4 0.3 21.4 HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 16.4;Kupffer cells: 41.5;Macrophages: 20.2;monocytes: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.5" "Group enriched" "Detected in many" 4 "granulocytes: 18.5;monocytes: 27.2" "Cell line enhanced" "Detected in many" "Karpas-707: 39.8;OE19: 40.1;TIME: 25.8" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" No No 6500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" 3.4 4.5 0.8 6.6 0.9 2.3 1.0 0.6 1.7 2.4 0.4 5.9 2.1 2.7 0.2 9.9 3.9 2.7 0.8 0.9 0.9 1.6 2.4 3.2 4.5 1.8 1.0 4.5 0.8 5.6 1.2 2.1 1.3 0.6 6.4 0.2 9.7 0.6 0.3 5.3 2.8 1.9 1.8 6.0 2.0 5.7 2.7 2.0 0.7 0.3 3.9 3.0 3.3 3.6 13.5 0.6 0.1 1.7 3.2 0.9 0.1 1.5 8.2 3.6 16.5 0.0 11.0 0.4 2.3 4.2 20.8 12.3 16.8 2.5 6.5 1.4 1.7 4.2 9.0 0.2 1.4 2.5 8.4 1.8 5.1 2.4 15.4 1.4 18.1 2.4 0.1 39.8 1.5 2.8 0.2 0.3 0.7 40.1 2.6 0.0 0.4 0.6 10.2 0.3 9.3 0.0 17.7 9.8 1.4 2.6 1.5 3.8 25.8 1.5 4.6 1.4 1.7 0.5 6.2 0.2 9.9 11.4 2.7 0.4 27.2 0.0 1.4 10.1 1.0 0.2 2.7 1.0 3.0 0.3 1.7 1.6 18.5 2.3 1.5 0.1 5.2 7.9 0.8 0.9 0.6 1.7 0.9 0.9 1.8 1.0 1.3 1.8 2.7 3.6 0.3 6.4 4.4 0.0 0.7 3.4 3.0 3.3 2.8 0.0 0.3 0.5 0.6 0.0 5.6 1.8 0.0 0.5 2.4 10.1 0.0 1.9 0.6 2.3 3.7 1.0 6.6 2.7 0.8 1.3 2.9 1.4 4.1 13.2 0.0 0.4 2.9 0.6 16.4 0.0 3.8 2.8 0.0 41.5 3.0 0.3 0.6 20.2 0.0 7.5 33.9 0.0 3.1 0.0 0.1 1.1 6.7 0.0 0.7 1.7 4.1 0.0 2.8 0.0 0.0 0.1 1.2 0.2 1.0 4.0 3.7 1.5 6.2 1.4 4.6 3.7 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 536.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 320.2;Granulosa cells: 257.5;Hepatocytes: 328.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 768.1;RT4: 524.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 16000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559" "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" 150.8 230.8 24.0 37.5 23.9 10.7 63.0 24.6 30.9 67.9 40.8 124.9 179.4 22.9 164.9 92.2 36.6 69.5 25.3 23.5 26.1 122.0 536.3 49.8 33.3 26.4 25.7 84.4 39.9 42.0 16.7 82.5 25.9 214.6 131.2 35.0 59.3 79.1 25.7 23.6 117.4 43.8 25.5 40.1 113.6 57.0 30.0 21.8 45.5 28.1 29.8 153.1 39.9 30.6 66.5 109.6 152.5 63.3 275.1 191.4 86.7 26.3 122.3 44.2 107.3 176.1 159.1 13.1 168.8 84.4 181.6 101.4 112.4 130.7 43.0 8.8 41.7 56.7 87.3 768.1 367.3 37.0 54.7 169.5 278.0 102.7 74.2 69.8 126.1 37.2 58.1 44.5 68.9 42.8 26.3 66.2 284.5 479.7 43.9 25.2 54.8 37.8 206.3 524.0 25.9 45.2 100.5 99.7 351.7 161.2 37.9 111.0 81.1 45.2 44.1 65.3 29.6 20.8 34.5 16.9 148.2 226.7 37.0 12.4 70.1 11.0 9.1 32.3 10.6 10.6 8.2 10.9 50.9 10.1 6.7 7.8 13.8 17.2 15.5 18.8 15.1 29.9 24.0 23.9 24.6 30.9 23.5 26.1 26.4 25.7 25.9 25.5 30.0 30.6 13.9 12.8 49.5 39.2 20.2 12.4 18.8 60.5 52.3 19.5 61.8 31.5 21.8 45.8 69.1 29.5 25.0 320.2 23.7 106.8 21.5 31.1 13.8 31.0 23.4 22.0 58.4 30.3 16.6 86.5 178.8 29.6 76.0 108.8 14.0 257.5 39.7 328.2 175.3 11.8 16.2 98.4 57.0 130.2 23.8 11.2 24.5 71.7 26.6 19.7 47.8 25.4 18.6 66.4 20.0 44.8 55.5 29.3 13.7 53.2 181.2 108.5 21.9 56.6 13.1 7.8 23.6 8.0 26.2 82.4 14.9 95.6 19.8 127.1 129.3 46.7 IL17RA "CD217, CDw217, hIL-17R, IL-17RA, IL17R" ENSG00000177663 "Interleukin 17 receptor A" Q96F46 22 17084954-17115694 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.9;Kupffer cells: 81.4;Macrophages: 61.4;monocytes: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HL-60: 59.9;NB-4: 52.5;THP-1: 74.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB024996 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 62000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB024996: " "unprognostic (1.92e-1)" "unprognostic (3.15e-1)" "unprognostic (1.65e-2)" "unprognostic (9.83e-2)" "unprognostic (7.66e-2)" "unprognostic (5.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-2)" "unprognostic (8.52e-2)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (1.96e-2)" "prognostic favorable (8.35e-4)" "unprognostic (2.16e-2)" "unprognostic (1.27e-1)" "unprognostic (6.51e-3)" 9.1 5.6 5.5 9.6 11.3 31.8 6.9 5.7 7.5 5.4 6.8 4.7 3.8 5.4 5.0 5.2 6.0 3.6 4.6 6.3 5.5 3.7 5.7 10.0 6.9 9.8 7.3 4.5 5.2 3.9 3.8 3.5 8.9 5.0 3.4 1.5 5.2 2.8 1.8 6.9 6.2 5.3 7.7 16.6 5.6 2.0 7.7 15.4 4.2 2.6 5.6 4.6 4.7 9.6 7.9 4.5 4.1 5.1 8.0 4.6 5.1 11.5 7.4 5.3 6.8 4.4 5.1 7.1 4.6 11.6 6.9 12.4 5.6 5.4 3.7 11.6 6.6 0.0 2.6 2.8 9.2 59.9 17.8 6.8 7.9 4.7 3.7 5.2 5.7 5.6 3.0 7.3 5.5 6.7 7.2 52.5 2.2 10.1 4.3 1.6 0.8 1.3 5.1 5.8 2.8 0.1 8.0 6.7 5.7 4.6 5.3 74.7 15.9 4.1 5.8 6.1 4.3 5.8 3.4 3.3 6.0 28.3 4.5 8.5 7.4 7.2 1.1 3.4 0.9 0.5 1.5 1.2 3.9 0.4 2.4 1.8 16.5 1.5 3.5 1.8 1.0 2.6 5.5 11.3 5.7 7.5 6.3 5.5 9.8 7.3 8.9 7.7 7.7 9.6 14.0 12.8 14.1 2.9 13.8 8.8 6.6 10.2 10.8 3.9 7.2 5.8 6.1 10.0 8.6 5.5 8.4 6.1 18.7 23.6 0.0 8.7 4.0 7.2 8.1 13.7 13.2 9.2 8.3 12.6 11.9 13.6 29.0 9.7 7.6 58.9 17.5 11.1 34.0 3.3 6.4 13.9 6.1 81.4 16.2 2.1 9.0 61.4 8.8 41.2 114.2 4.3 28.8 12.5 11.4 12.2 12.4 4.5 10.3 9.1 14.7 3.4 8.0 2.9 13.1 10.4 10.0 3.0 13.4 9.0 6.8 6.4 25.4 8.1 12.4 9.6 IL17RC IL17-RL ENSG00000163702 "Interleukin 17 receptor C" Q8NAC3 3 9917074-9933630 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.7;myeloid DC: 2.1" "Group enriched" "Detected in many" 18 "dendritic cells: 2.1;monocytes: 1.7" "Cell line enhanced" "Detected in many" "ASC diff: 71.2;ASC TERT1: 43.6;HSkMC: 40.7;T-47d: 41.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019885, CAB026255" Approved "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "CAB026255: , HPA019885: AB_1851664" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.38e-4)" "unprognostic (2.58e-2)" "unprognostic (1.45e-3)" "unprognostic (8.60e-2)" "unprognostic (7.11e-2)" "unprognostic (1.38e-2)" "unprognostic (5.27e-2)" "unprognostic (4.30e-2)" "unprognostic (5.98e-2)" "unprognostic (9.35e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.48e-1)" "unprognostic (2.83e-1)" 17.5 32.2 5.5 4.2 5.5 3.8 18.8 5.0 7.1 16.6 6.0 21.4 15.0 15.0 4.9 23.6 14.8 7.4 19.9 5.7 6.6 15.7 63.7 9.2 1.8 6.2 5.9 12.9 15.3 17.0 27.9 2.9 4.9 31.3 4.7 1.1 23.7 12.6 16.9 32.2 15.5 6.9 6.6 5.9 16.8 1.7 7.0 1.9 13.9 15.7 2.4 17.9 19.4 5.0 7.3 4.6 1.5 4.5 71.2 43.6 10.8 10.0 23.4 12.3 19.5 1.6 19.9 0.0 11.8 15.8 8.7 5.1 2.0 10.7 4.1 4.7 6.0 1.9 13.6 6.6 22.0 0.1 0.0 40.7 8.7 14.9 3.3 5.7 10.6 0.0 0.8 9.1 9.8 11.3 0.2 0.4 0.9 2.6 31.4 4.5 5.1 2.6 9.1 4.1 4.0 6.4 6.1 13.7 10.8 0.4 41.2 0.8 8.9 13.4 6.4 5.9 6.7 0.1 0.3 0.0 21.0 0.9 9.8 0.0 1.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 5.5 5.5 5.0 7.1 5.7 6.6 6.2 5.9 4.9 6.6 7.0 5.0 10.1 0.0 0.5 18.9 2.0 10.8 18.6 11.2 12.5 2.1 30.2 24.1 3.4 18.6 11.7 1.8 0.0 5.8 2.6 22.4 3.9 15.1 0.5 8.0 8.7 7.8 14.4 6.5 3.8 21.1 4.7 15.7 15.8 10.0 0.0 14.0 11.4 43.9 11.0 1.7 4.8 25.3 16.2 6.0 7.8 1.4 19.0 6.0 14.2 4.7 3.4 25.5 1.0 7.1 0.9 13.2 29.8 17.0 1.7 25.7 53.2 17.7 6.9 1.6 19.7 12.8 12.4 0.8 0.5 13.3 19.9 2.9 2.1 11.9 20.0 16.6 IQSEC2 "BRAG1, IQ-ArfGEF, KIAA0522, MRX1, MRX18, MRX78" ENSG00000124313 "IQ motif and Sec7 domain ArfGEF 2" Q5JU85 X 53225828-53321350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 54.0;Late spermatids: 41.6;Proximal enterocytes: 42.1;Proximal tubular cells: 52.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 10.4;plasmacytoid DC: 10.6" "Group enriched" "Detected in many" 16 "dendritic cells: 10.6;monocytes: 10.4" "Cell line enhanced" "Detected in many" "A549: 47.3;GAMG: 58.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003973, HPA076533" Approved "Vesicles,Lipid droplets" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 47: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Lipid droplets" "HPA003973: AB_2280343, HPA076533: " "unprognostic (1.85e-1)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (1.32e-1)" "unprognostic (4.66e-3)" "unprognostic (6.02e-2)" "unprognostic (2.80e-1)" "unprognostic (3.78e-2)" "unprognostic (2.82e-1)" "unprognostic (9.05e-2)" "unprognostic (1.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.56e-2)" "unprognostic (1.75e-1)" "unprognostic (4.30e-2)" "prognostic favorable (2.38e-4)" 10.8 18.8 18.3 5.8 22.4 2.4 9.9 9.8 32.3 9.7 0.0 14.9 12.5 12.0 4.4 9.5 10.7 6.1 11.2 35.8 0.0 19.4 1.9 8.7 2.8 2.4 0.1 7.6 9.0 14.1 10.9 3.8 2.8 12.0 7.1 3.0 14.9 8.8 58.7 8.9 14.2 7.3 0.3 5.3 10.4 9.9 0.2 3.4 9.7 34.0 3.4 12.1 9.8 14.2 4.8 47.3 1.8 4.4 6.5 13.1 5.3 7.7 13.4 6.2 10.9 1.2 18.2 0.3 12.4 18.3 58.5 6.4 1.7 7.7 4.4 4.8 8.3 5.4 20.8 1.3 14.2 0.2 2.8 9.8 11.8 16.1 9.0 14.4 8.5 0.1 17.3 5.3 12.4 11.2 0.0 1.0 14.6 14.2 21.0 3.5 3.7 6.0 9.0 10.1 1.9 1.8 18.0 11.0 7.5 8.3 15.7 2.3 9.5 5.6 10.6 3.1 3.5 1.5 0.2 0.2 34.6 3.5 3.1 0.1 10.4 0.5 0.0 3.7 0.1 0.2 0.0 0.0 5.4 0.1 0.1 0.0 0.6 0.0 2.0 10.6 0.0 2.3 18.3 22.4 9.8 32.3 35.8 0.0 2.4 0.1 2.8 0.3 0.2 14.2 8.4 6.4 5.9 15.0 1.4 4.0 6.7 11.5 7.4 1.5 12.2 9.5 4.0 12.8 9.3 14.7 0.0 8.0 2.0 21.1 21.5 5.2 18.0 5.4 3.5 6.2 3.6 0.8 54.0 7.1 6.5 6.6 8.2 4.7 3.8 9.1 6.4 0.9 14.7 0.0 25.7 9.7 8.2 12.0 5.0 41.6 1.5 14.1 10.6 17.8 11.9 5.0 0.0 9.5 2.5 5.5 12.6 2.2 1.0 7.0 42.1 52.4 7.6 0.1 0.0 2.7 8.4 0.8 1.5 9.3 3.8 4.5 1.5 2.5 10.7 14.6 ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Group enriched" "Detected in many" 6 "dendritic cells: 417.6;Hofbauer cells: 652.4;Kupffer cells: 485.9;Langerhans cells: 259.1;Macrophages: 527.4;monocytes: 463.8;NK-cells: 959.9;T-cells: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "THP-1: 812.4;U-937: 615.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" 54.5 23.2 8.2 175.2 9.5 376.2 15.4 13.1 9.3 15.5 11.7 25.2 23.8 8.5 2.8 16.2 17.0 36.4 11.8 7.7 14.2 8.4 23.4 78.0 169.1 29.5 19.9 7.2 11.3 5.1 4.6 44.4 28.1 8.8 13.9 1.1 19.5 9.2 6.8 9.3 32.8 46.4 23.9 137.2 29.1 5.9 26.2 87.2 7.3 7.6 68.4 46.3 5.9 50.4 1.9 4.8 0.0 0.0 0.0 0.3 1.7 0.0 2.7 0.1 0.0 0.4 0.4 17.9 128.1 0.2 0.6 0.5 0.0 0.2 0.0 1.5 1.4 18.2 0.0 3.2 0.1 106.6 27.5 1.6 0.1 0.5 0.3 0.1 0.3 58.0 0.7 1.4 7.0 4.0 117.8 126.1 0.4 0.4 2.4 1.5 23.2 64.6 4.7 0.0 0.6 1.3 3.4 2.5 1.7 0.0 0.4 812.4 2.5 0.2 6.6 0.4 3.7 0.8 5.9 2.9 0.1 615.0 0.9 186.6 1848.8 1224.1 726.7 1144.9 326.6 86.1 349.7 506.5 1031.4 115.2 233.1 396.5 1386.1 585.5 1183.5 165.5 288.0 3034.2 8.2 9.5 13.1 9.3 7.7 14.2 29.5 19.9 28.1 23.9 26.2 50.4 7.1 16.0 29.6 0.3 81.7 5.5 0.5 9.6 0.6 0.0 4.1 6.5 4.0 14.3 18.6 5.5 0.0 4.0 417.6 0.3 0.0 3.4 1.0 0.6 0.5 16.8 0.0 19.6 0.5 0.4 4.8 5.3 2.6 0.7 24.1 8.2 9.7 8.6 652.4 0.0 0.3 0.2 2.0 485.9 259.1 2.8 0.6 527.4 5.4 27.2 463.8 0.4 959.9 0.0 0.2 0.6 0.1 1.5 50.5 0.6 1.8 4.2 3.6 0.8 6.6 2.1 3.2 0.2 1.0 0.9 5.1 5.6 254.5 0.0 0.3 0.7 ITIH1 "H1P, IATIH, ITIH" ENSG00000055957 "Inter-alpha-trypsin inhibitor heavy chain 1" P19827 3 52777595-52792068 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 782 "liver: 1504.9" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 1087.0" "Cancer enriched" "Detected in some" 598 "liver cancer: 329.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 5.3;Hep G2: 1.7;HL-60: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041639, HPA042049" Approved Approved Vesicles "Secreted to blood" NA NA 4490000 59000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA041639: AB_10796349, HPA042049: AB_10797379" "unprognostic (1.87e-4)" "unprognostic (1.31e-3)" "unprognostic (2.38e-1)" "unprognostic (8.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.64e-3)" "prognostic favorable (1.89e-5)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-2)" "unprognostic (4.53e-4)" "unprognostic (4.02e-3)" "unprognostic (5.70e-3)" "unprognostic (2.08e-1)" "unprognostic (2.24e-2)" 0.8 0.3 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.2 1504.9 0.1 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 1.9 0.4 0.4 0.0 0.4 0.0 0.1 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.1 0.0 29.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 18.5 1087.0 0.1 0.0 0.0 0.0 0.0 20.2 0.0 1.7 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.1 JPH4 "JPHL1, KIAA1831" ENSG00000092051 "Junctophilin 4" Q96JJ6 14 23568035-23578790 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.2;pituitary gland: 66.5" "Group enriched" "Detected in some" 13 "Bipolar cells: 191.4;Horizontal cells: 410.5" "Cancer enhanced" "Detected in some" "glioma: 6.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.8;myeloid DC: 3.2" "Group enriched" "Detected in many" 8 "dendritic cells: 3.2;monocytes: 2.8" "Group enriched" "Detected in some" 6 "SCLC-21H: 14.2;SH-SY5Y: 35.4;U-2 OS: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045022 Approved Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA045022: " "unprognostic (3.30e-2)" "unprognostic (1.91e-3)" "unprognostic (5.05e-3)" "unprognostic (7.41e-2)" "unprognostic (2.04e-1)" "unprognostic (1.84e-1)" "unprognostic (3.77e-3)" "unprognostic (5.98e-4)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (3.89e-3)" "unprognostic (1.15e-2)" "unprognostic (3.15e-2)" "unprognostic (2.10e-2)" "unprognostic (1.91e-1)" "unprognostic (2.13e-2)" "unprognostic (4.96e-3)" 1.5 11.7 83.7 1.0 88.5 0.2 1.0 25.2 126.2 8.4 0.0 1.7 0.8 24.3 5.2 0.4 13.7 0.5 0.3 115.4 29.3 3.0 0.3 2.5 1.0 14.5 11.0 13.6 0.5 1.8 66.5 0.5 11.2 12.3 0.6 12.5 0.3 36.8 0.2 0.9 1.3 12.9 7.2 2.6 0.9 1.4 31.7 0.3 0.4 0.5 0.6 1.6 6.6 57.2 0.0 0.0 0.7 3.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 4.4 0.0 0.2 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.7 14.2 35.4 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.3 2.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 83.7 88.5 25.2 126.2 115.4 29.3 14.5 11.0 11.2 7.2 31.7 57.2 0.3 0.0 0.6 0.7 0.0 0.0 0.2 0.0 0.0 191.4 0.2 0.1 1.3 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.3 0.3 5.7 1.7 1.8 0.0 22.1 0.0 0.0 1.4 0.0 0.1 5.1 1.2 1.8 0.0 2.0 410.5 18.3 0.2 0.0 1.3 9.3 0.2 10.8 0.9 0.0 0.0 0.1 1.6 0.0 15.6 0.4 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 7.7 13.1 0.1 2.3 0.5 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.8 KCTD12 "C13orf2, KIAA1778, PFET1" ENSG00000178695 "Potassium channel tetramerization domain containing 12" Q96CX2 13 76880175-76886405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 281.2;Endothelial cells: 192.2;Enteroendocrine cells: 386.7;Hofbauer cells: 218.9;Kupffer cells: 395.9;Macrophages: 221.3;monocytes: 206.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 3.9;myeloid DC: 3.7" "Group enriched" "Detected in many" 17 "dendritic cells: 3.7;granulocytes: 1.0;monocytes: 3.9" "Cell line enhanced" "Detected in many" "ASC diff: 111.4;HUVEC TERT2: 229.0;TIME: 186.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056987, HPA077376" Supported Approved Mitochondria NA NA 21000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA056987: , HPA077376: " "unprognostic (6.42e-2)" "unprognostic (2.67e-1)" "unprognostic (5.13e-1)" "unprognostic (1.04e-3)" "unprognostic (5.82e-2)" "unprognostic (3.98e-2)" "unprognostic (2.02e-1)" "unprognostic (1.32e-3)" "unprognostic (1.35e-2)" "unprognostic (1.90e-1)" "unprognostic (9.83e-3)" "unprognostic (1.23e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.11e-2)" "unprognostic (1.65e-2)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" 76.1 27.8 21.4 55.7 20.1 12.0 52.4 27.0 20.8 44.5 12.4 39.5 22.5 51.3 17.8 38.3 75.0 55.0 22.6 26.9 27.8 31.0 13.9 58.0 39.4 36.2 33.5 47.1 12.5 25.2 6.4 83.9 31.4 14.7 42.5 3.4 20.0 18.5 16.6 22.9 28.1 65.3 37.0 64.8 28.0 26.9 31.4 18.3 16.4 37.1 33.4 39.2 17.4 34.4 1.7 1.5 15.3 0.0 111.4 52.5 4.3 6.9 1.5 4.2 5.5 0.5 0.3 0.0 3.8 18.8 4.9 53.9 6.6 66.4 3.5 1.5 35.1 0.2 38.3 0.0 4.7 18.6 0.1 21.4 21.5 2.7 48.9 8.5 229.0 13.2 0.3 0.2 53.9 1.4 8.5 0.3 7.8 16.6 7.7 0.4 7.4 19.6 17.7 0.2 4.3 7.9 17.3 0.5 2.2 18.5 1.0 12.1 186.0 2.7 4.9 0.4 14.0 2.7 0.5 0.0 42.5 4.0 16.1 0.0 3.9 0.7 0.0 2.5 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 1.0 0.0 1.5 1.9 0.0 0.9 21.4 20.1 27.0 20.8 26.9 27.8 36.2 33.5 31.4 37.0 31.4 34.4 281.2 25.6 8.4 2.9 7.5 40.0 2.7 11.9 28.5 4.4 11.2 27.3 21.8 4.3 16.3 97.5 14.6 3.0 30.4 19.7 17.6 6.5 3.6 4.9 44.6 192.2 386.7 6.1 4.8 0.6 90.6 80.0 12.2 3.3 7.0 53.1 61.1 2.5 218.9 0.0 11.5 71.5 12.2 395.9 75.4 11.8 157.2 221.3 51.6 45.9 206.7 4.8 7.2 0.5 0.9 0.5 15.7 44.8 7.6 4.5 0.7 7.5 72.8 1.5 26.3 153.2 32.2 1.9 7.0 16.9 34.4 4.2 5.5 24.0 46.6 1.9 KLF10 "EGRA, TIEG, TIEG1" ENSG00000155090 "Kruppel like factor 10" Q13118 8 102648784-102655725 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 409.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (6.67e-2)" "unprognostic (1.29e-2)" "unprognostic (4.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.42e-3)" "unprognostic (7.76e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.61e-5)" "unprognostic (4.88e-1)" "unprognostic (2.74e-2)" "unprognostic (3.44e-2)" "unprognostic (3.77e-1)" "unprognostic (6.60e-3)" "unprognostic (3.27e-2)" "unprognostic (8.23e-2)" "unprognostic (7.51e-3)" "unprognostic (1.06e-1)" 65.4 28.8 6.1 25.4 7.2 152.8 40.3 4.9 14.3 37.6 8.2 58.4 28.3 40.7 17.0 39.6 42.4 64.9 33.5 7.8 6.8 40.0 95.7 71.3 22.6 6.3 6.8 25.0 126.2 15.2 16.4 71.1 6.0 45.4 46.1 11.4 32.0 33.3 158.9 72.1 26.2 60.3 6.1 34.9 41.1 26.7 6.4 45.6 30.0 122.9 22.3 46.4 27.4 6.2 22.3 32.4 17.3 15.7 30.4 66.3 30.8 43.0 22.9 26.8 12.8 17.3 42.2 35.5 38.2 39.1 49.4 24.0 10.0 106.5 35.4 20.3 17.4 27.6 24.4 15.9 24.7 16.3 41.3 94.5 105.2 36.8 42.1 62.1 60.0 6.8 18.2 68.3 87.2 36.2 17.8 28.3 13.5 58.5 78.8 7.2 59.7 34.0 38.8 67.6 25.4 27.6 64.0 26.3 35.0 25.0 25.4 19.1 67.0 55.9 39.5 65.3 44.0 61.6 51.7 32.6 52.1 20.1 32.2 17.2 52.5 14.3 16.5 48.2 9.0 17.1 12.5 17.2 57.2 5.8 3.1 12.7 5.3 15.6 26.0 10.1 18.4 34.7 6.1 7.2 4.9 14.3 7.8 6.8 6.3 6.8 6.0 6.1 6.4 6.2 195.5 141.1 74.9 1.0 49.2 137.1 167.6 117.3 409.8 3.5 115.9 119.6 117.9 40.0 56.6 44.1 6.2 52.3 41.7 74.6 9.8 58.3 8.5 110.1 121.6 134.7 94.2 11.2 6.7 43.3 87.7 147.7 46.4 183.3 100.1 34.9 94.2 53.5 61.1 8.4 0.6 49.2 93.6 73.1 185.6 10.4 66.5 117.6 76.5 7.5 83.7 7.7 8.2 0.5 0.5 42.7 41.2 29.3 51.4 136.7 35.5 43.8 50.7 2.6 26.3 157.1 124.1 18.7 30.7 222.9 164.8 72.7 47.8 40.6 48.1 58.8 LAMB2 "LAMS, NPHS5" ENSG00000172037 "Laminin subunit beta 2" P55268 3 49121114-49133118 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 151.8;Leydig cells: 146.3;Peritubular cells: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 299.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000053, HPA001895, HPA050033, CAB078160" Supported Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 25000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "CAB000053: AB_2313665, CAB078160: AB_2665799, HPA001895: AB_1079227, HPA050033: " "unprognostic (1.12e-2)" "unprognostic (4.40e-2)" "unprognostic (5.14e-3)" "unprognostic (1.10e-1)" "unprognostic (4.08e-1)" "unprognostic (4.01e-1)" "unprognostic (5.59e-2)" "unprognostic (6.80e-2)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (1.26e-1)" "unprognostic (4.96e-2)" "unprognostic (1.21e-3)" "unprognostic (1.78e-1)" "unprognostic (4.38e-2)" "unprognostic (6.20e-2)" "unprognostic (1.24e-2)" 75.2 73.2 12.8 18.2 14.2 2.6 58.2 15.1 14.9 68.0 47.7 63.1 24.6 72.7 25.5 31.9 63.8 62.2 169.1 13.1 14.5 41.3 31.7 55.1 16.9 20.0 14.8 94.4 32.7 104.7 15.4 99.0 15.4 50.4 18.0 11.7 40.3 81.0 67.5 40.9 32.5 80.2 14.1 29.8 48.4 21.4 17.3 6.7 60.2 70.0 12.8 52.2 55.9 13.5 15.7 38.7 34.4 122.0 196.3 201.5 31.1 131.9 161.8 73.8 75.7 18.3 52.0 0.2 44.4 299.0 38.3 49.3 30.0 47.6 52.3 0.1 9.5 6.9 63.4 32.1 132.5 0.3 0.3 176.9 69.4 61.6 62.1 184.3 75.9 0.0 4.1 0.1 61.4 30.3 0.1 0.3 15.1 20.7 32.0 0.2 16.6 0.5 53.5 19.1 0.2 20.4 74.9 42.9 68.3 57.5 93.4 0.9 126.9 82.2 34.9 28.5 35.4 0.1 0.4 0.4 39.1 0.3 57.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 14.2 15.1 14.9 13.1 14.5 20.0 14.8 15.4 14.1 17.3 13.5 83.7 118.6 53.5 26.1 2.4 31.2 13.9 33.6 33.0 1.7 39.4 40.5 151.8 37.1 43.6 55.2 6.2 11.3 0.9 3.6 5.9 26.4 3.5 15.4 24.4 77.8 0.0 0.4 0.2 9.4 6.4 120.1 50.4 27.2 1.3 88.9 94.9 49.9 10.4 8.4 0.4 3.1 32.6 10.1 31.1 12.3 146.3 7.5 42.7 15.9 3.5 46.7 2.1 1.0 0.6 14.1 14.9 140.7 0.5 10.2 16.4 28.6 11.2 2.6 118.3 80.8 92.3 4.3 8.6 14.2 24.4 9.4 3.8 27.6 5.6 9.3 LAMTOR1 "C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1" ENSG00000149357 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1" Q6IAA8 11 72085895-72103297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002997 Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus" "Vesicles, Plasma membrane" "HPA002997: AB_1845531" "unprognostic (7.32e-2)" "unprognostic (1.79e-1)" "unprognostic (3.94e-2)" "unprognostic (3.77e-2)" "unprognostic (2.30e-1)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.00e-1)" "unprognostic (2.18e-1)" "unprognostic (1.94e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-3)" "unprognostic (1.78e-3)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" 100.7 143.8 171.2 69.1 177.8 118.6 96.2 173.2 180.4 87.0 162.1 88.6 67.5 86.5 90.0 114.1 74.9 65.8 131.9 163.5 169.5 129.5 114.2 91.3 80.6 177.4 177.2 81.5 85.6 87.0 92.0 67.4 174.9 102.4 76.5 46.6 85.8 71.7 126.4 89.9 82.5 73.7 175.4 130.9 96.6 41.2 176.1 75.4 112.3 109.3 79.4 88.5 77.9 172.5 94.2 181.0 97.3 132.0 224.7 152.3 97.6 129.0 201.6 206.2 151.7 230.9 139.7 93.1 162.3 216.9 214.2 138.1 171.1 260.1 155.8 117.8 99.3 245.6 108.5 156.5 291.4 97.2 147.7 252.3 199.2 224.4 224.0 116.4 173.1 102.5 104.1 96.0 211.4 295.6 86.2 146.1 93.9 291.8 194.9 73.7 178.9 78.8 246.8 195.1 65.7 103.3 127.6 127.5 343.7 106.4 192.6 93.2 125.3 137.5 98.0 323.8 93.0 111.6 139.0 80.4 81.8 81.8 113.0 113.4 414.3 274.1 80.6 228.8 77.7 132.1 75.6 81.1 332.6 146.2 63.4 77.9 229.5 122.8 180.6 197.1 98.8 397.5 171.2 177.8 173.2 180.4 163.5 169.5 177.4 177.2 174.9 175.4 176.1 172.5 132.6 44.8 71.6 9.1 109.7 55.7 161.7 271.1 117.8 58.5 159.9 195.7 66.4 121.5 120.2 128.8 12.5 266.5 110.7 235.4 295.4 276.4 12.4 61.2 98.9 134.9 116.4 133.5 9.8 340.2 300.1 111.6 71.4 85.2 97.7 71.5 142.1 86.9 468.0 77.4 12.9 140.2 170.9 248.5 111.6 19.2 107.8 311.5 113.8 8.4 413.6 223.7 177.1 10.1 24.2 307.3 202.6 102.7 87.9 193.4 230.3 370.9 61.0 56.1 111.7 102.5 116.3 58.7 103.3 126.1 55.4 282.0 89.4 178.5 170.8 157.2 LAP3 "LAP, LAPEP, PEPS" ENSG00000002549 "Leucine aminopeptidase 3" P28838 4 17577198-17607972 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 230.6;Hofbauer cells: 262.1;Proximal tubular cells: 274.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029606, HPA029607" Enhanced Supported Nucleoplasm,Midbody,Cytosol Yes No 3500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Nucleoplasm, Midbody" "HPA029606: AB_10599288, HPA029607: AB_10611381" "unprognostic (2.10e-2)" "unprognostic (1.01e-1)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (2.87e-1)" "unprognostic (2.16e-1)" "unprognostic (1.55e-1)" "unprognostic (5.33e-2)" "unprognostic (1.44e-3)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (4.29e-3)" "unprognostic (1.73e-1)" "unprognostic (3.28e-2)" "unprognostic (3.06e-1)" "unprognostic (8.79e-2)" 92.8 52.6 33.0 131.4 34.8 59.2 60.3 39.0 42.9 30.7 31.4 60.3 78.3 34.4 25.4 44.6 45.4 67.3 65.0 31.8 36.3 106.3 190.4 100.6 150.4 46.3 37.7 24.0 30.9 61.0 22.1 70.9 42.2 36.7 62.0 20.0 67.7 31.0 68.1 40.3 61.3 76.2 45.6 94.1 55.3 43.8 41.9 56.8 46.4 63.8 94.3 82.8 25.3 42.9 51.7 44.4 41.6 39.4 80.5 97.9 0.4 79.6 89.1 282.3 340.3 81.4 96.1 202.0 51.7 61.6 167.9 31.3 157.7 56.3 106.7 77.7 45.2 112.1 47.3 107.6 94.1 102.3 69.2 100.0 35.3 92.7 48.6 32.3 99.7 52.2 110.6 139.9 67.6 55.6 91.9 139.5 87.1 96.3 83.9 139.8 39.8 102.7 73.5 59.6 61.4 50.2 72.9 44.4 161.1 57.3 37.9 39.1 65.2 71.3 48.5 76.1 140.6 127.7 208.8 172.7 96.3 167.2 70.8 43.1 200.6 44.7 33.7 210.0 31.0 32.7 31.2 36.3 204.6 23.5 26.7 28.3 28.1 54.0 158.1 116.6 60.2 135.8 33.0 34.8 39.0 42.9 31.8 36.3 46.3 37.7 42.2 45.6 41.9 42.9 230.6 28.9 49.6 10.7 34.4 22.0 26.1 60.1 21.6 8.1 53.5 41.7 48.9 18.6 44.1 27.6 2.1 35.9 68.3 44.2 117.4 68.6 100.5 67.3 45.7 129.7 16.3 31.7 6.4 109.2 54.7 42.0 29.6 40.7 64.1 29.4 71.0 95.5 262.1 6.7 9.6 35.6 42.7 92.1 50.5 31.7 23.0 141.9 42.7 18.7 195.0 103.8 28.8 9.5 21.2 53.3 31.8 35.0 71.2 26.9 52.4 274.0 92.5 15.4 32.9 31.3 57.8 95.7 13.7 32.5 22.9 55.7 42.4 80.7 45.6 27.1 LAPTM4A "HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp" ENSG00000068697 "Lysosomal protein transmembrane 4 alpha" Q15012 2 20032650-20051628 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 1393.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031402, HPA031404, HPA068554" Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "Plasma membrane" "HPA031402: AB_10669882, HPA031404: AB_10670293, HPA068554: AB_2686003" "unprognostic (2.01e-1)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (5.73e-1)" "unprognostic (6.04e-2)" "unprognostic (3.00e-2)" "unprognostic (1.53e-3)" "unprognostic (5.37e-2)" "unprognostic (1.27e-1)" "unprognostic (3.65e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (8.70e-2)" "unprognostic (1.05e-2)" "unprognostic (7.78e-3)" "unprognostic (2.18e-2)" "unprognostic (7.98e-3)" "unprognostic (2.36e-1)" 360.5 451.0 116.8 177.1 114.9 199.5 338.5 120.7 146.8 469.8 150.8 256.2 219.6 507.6 339.7 315.4 370.1 383.7 322.5 112.7 130.2 460.9 409.2 308.0 160.1 123.3 122.2 460.3 290.8 289.2 155.6 397.6 128.1 306.3 233.9 59.1 306.0 611.8 204.4 247.2 227.7 412.2 130.1 190.9 240.5 389.3 125.5 122.8 365.8 234.8 178.5 342.1 248.7 128.0 417.7 228.8 136.4 283.2 1393.4 1031.8 509.1 514.3 651.8 349.3 393.6 180.5 398.4 73.2 116.2 637.9 356.9 400.7 115.0 250.6 317.8 181.2 183.2 112.4 244.3 520.1 534.8 86.7 294.9 691.7 501.2 338.7 386.4 481.9 367.6 62.2 86.6 135.8 527.5 243.3 53.8 114.0 299.2 353.1 207.1 89.3 397.5 139.7 858.6 347.7 214.8 207.3 480.4 390.5 335.9 492.9 169.6 70.1 467.5 575.7 203.8 500.3 336.5 221.7 349.2 118.3 455.3 172.8 234.4 737.8 382.3 289.3 94.6 324.9 116.4 197.4 112.9 106.9 269.2 192.3 126.7 113.7 200.1 124.3 393.4 226.9 119.3 427.0 116.8 114.9 120.7 146.8 112.7 130.2 123.3 122.2 128.1 130.1 125.5 128.0 351.7 195.5 203.1 39.2 156.5 659.0 601.1 1210.5 339.2 24.4 330.3 306.1 211.7 380.3 727.7 553.6 12.5 224.4 109.8 174.8 162.4 539.4 1235.7 195.7 407.1 384.0 138.1 65.0 15.0 347.6 1035.3 896.8 111.6 286.0 521.9 445.7 331.3 519.4 311.3 20.2 14.3 203.6 767.0 299.3 716.0 1080.9 835.3 254.4 588.7 39.4 278.0 315.3 48.4 34.7 18.7 289.4 246.2 600.7 156.8 331.2 171.5 940.9 506.7 24.7 532.5 389.4 583.0 356.3 173.5 268.2 709.8 302.9 146.4 579.1 224.8 500.9 LGALS1 GBP ENSG00000100097 "Galectin 1" P09382 22 37675636-37679802 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3949.7;Langerhans cells: 4906.5;monocytes: 7118.4;Smooth muscle cells: 4703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 1649.6" "HPA000646, HPA000687, HPA001130, CAB002157" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" No Yes 10000000 20000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB002157: AB_563734, HPA000646: AB_1078935, HPA000687: AB_2756309, HPA001130: AB_2756311" "unprognostic (1.65e-1)" "unprognostic (8.13e-2)" "unprognostic (5.13e-2)" "prognostic favorable (2.36e-5)" "unprognostic (6.38e-2)" "unprognostic (2.67e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.22e-3)" "unprognostic (4.91e-3)" "unprognostic (2.51e-1)" "unprognostic (6.16e-3)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.18e-10)" "unprognostic (2.24e-2)" "unprognostic (8.13e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (5.10e-4)" 1921.2 778.5 482.4 523.8 520.7 324.7 1490.9 613.5 695.3 1805.7 465.2 1634.7 197.7 2270.1 196.8 387.4 1147.0 556.0 1397.4 457.7 549.0 362.4 277.4 920.2 176.7 694.5 576.1 1440.2 155.5 188.1 254.8 426.1 661.5 903.0 207.2 39.5 397.5 756.3 1172.9 472.8 475.3 1353.4 593.8 460.7 582.7 244.9 624.9 153.9 290.9 691.9 116.9 1059.7 1156.4 782.4 2850.9 1664.3 36.5 1440.9 3314.6 6505.1 32.7 6450.7 7619.4 4761.9 4716.9 189.6 368.3 3.3 649.1 6661.4 1609.2 296.3 58.8 4309.2 1663.3 2917.2 30.9 251.3 1606.3 791.1 2155.3 145.1 3167.7 4031.7 294.2 3785.7 1609.9 4271.1 5325.7 1.7 186.6 1163.4 3771.1 1287.6 5.2 2038.4 14.3 629.6 3914.9 5.4 2388.6 799.7 2000.0 6.4 5.5 843.4 1287.4 224.3 1644.5 66.7 1187.2 1689.0 7122.0 6224.0 3070.2 2788.9 3349.3 701.8 530.6 13.6 7291.9 762.0 2535.9 1086.5 3047.4 110.2 766.5 2320.4 113.6 567.7 694.9 754.2 3653.1 287.5 114.3 478.1 122.2 415.4 2556.7 899.2 1514.7 4667.0 482.4 520.7 613.5 695.3 457.7 549.0 694.5 576.1 661.5 593.8 624.9 782.4 1505.8 166.7 90.4 12.7 294.3 730.3 144.0 2796.6 49.5 10.0 144.2 477.9 986.3 74.4 213.4 163.7 6.2 88.0 466.5 49.9 17.6 690.2 30.9 183.0 3011.6 1063.6 3.0 74.9 7.5 90.4 1573.3 2540.4 28.1 230.3 540.0 172.2 653.2 614.1 3949.7 8.4 5.4 8.4 339.7 2159.0 4906.5 106.4 975.5 1700.0 2856.6 15.9 7118.4 278.0 588.1 4.0 17.1 233.5 6.1 1300.7 590.9 118.8 0.5 28.7 109.8 45.4 1650.1 1873.6 4703.8 33.8 13.1 18.2 588.0 151.5 767.5 197.2 11.6 57.0 LGALS2 HL14 ENSG00000100079 "Galectin 2" P05162 22 37570248-37582616 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 335.5;intestine: 198.0;kidney: 153.0;pancreas: 211.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 779.2;Distal enterocytes: 695.4;Langerhans cells: 982.8;Proximal enterocytes: 2724.7;Proximal tubular cells: 1764.8;Undifferentiated cells: 749.3" "Cancer enhanced" "Detected in all" "renal cancer: 54.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 27 "classical monocyte: 1464.7;intermediate monocyte: 553.8;myeloid DC: 1207.2" "Group enriched" "Detected in all" 50 "dendritic cells: 1207.2;monocytes: 1464.7" "Group enriched" "Detected in many" 4 "CACO-2: 109.4;Hep G2: 62.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA003536, CAB025198" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoplasm "CAB025198: , HPA003536: AB_1078936" "unprognostic (1.37e-3)" "unprognostic (4.11e-3)" "unprognostic (1.32e-3)" "unprognostic (4.32e-2)" "unprognostic (1.74e-1)" "unprognostic (2.91e-3)" "unprognostic (3.19e-1)" "unprognostic (9.92e-2)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.15e-2)" "unprognostic (5.19e-1)" "unprognostic (2.33e-3)" "unprognostic (1.80e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (1.21e-1)" 7.5 1.4 0.6 23.5 1.4 19.2 5.4 0.2 1.1 1.8 0.2 55.0 41.2 3.6 1.0 5.2 4.4 335.5 1.6 0.5 1.0 153.0 5.0 8.6 60.7 1.6 1.2 0.9 211.5 0.2 0.1 1.7 1.4 2.2 81.1 0.1 2.1 0.7 1.9 9.9 198.0 5.2 0.4 59.2 10.7 0.6 1.1 41.3 1.0 0.7 64.0 8.2 0.5 3.4 2.8 1.5 0.9 1.0 0.0 0.0 1.1 1.7 0.0 0.0 0.0 109.4 0.1 0.4 0.3 0.0 0.3 1.7 0.0 0.0 0.0 0.2 1.1 0.0 0.0 62.5 0.3 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 2.8 0.0 1.0 0.4 21.2 0.3 0.0 0.9 1.3 0.0 0.0 0.0 0.3 1.7 1.9 2.4 0.5 1.6 1.7 6.4 2.0 1.0 4.3 0.8 0.0 0.2 0.3 2.7 0.2 1.3 7.7 1464.7 8.7 1.8 553.8 3.3 9.9 1.8 2.1 1207.2 2.3 2.3 1.9 26.8 2.3 39.7 9.6 3.0 981.5 0.6 1.4 0.2 1.1 0.5 1.0 1.6 1.2 1.4 0.4 1.1 3.4 1.6 6.4 3.9 0.0 16.4 17.1 0.1 0.5 0.0 0.0 13.2 7.5 0.3 779.2 1.4 29.5 0.0 0.2 7.0 695.4 127.2 26.3 0.1 0.1 0.3 2.3 73.7 4.8 0.1 206.7 0.3 3.2 5.6 0.2 2.5 0.0 0.7 1.9 26.4 0.0 0.1 413.0 0.0 100.8 982.8 0.3 0.6 150.8 24.9 0.0 164.8 0.0 4.1 0.0 0.1 291.6 331.6 0.0 0.9 0.3 2724.7 1764.8 2.1 0.0 0.0 0.3 2.3 0.0 0.4 0.1 12.4 0.3 8.6 0.0 749.3 0.3 LGALS3 "GALIG, LGALS2, MAC-2" ENSG00000131981 "Galectin 3" P17931 14 55124110-55145423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Immunity, Innate immunity, mRNA processing, mRNA splicing" "IgE-binding protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1194.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4097.0;Paneth cells: 3445.9;Proximal enterocytes: 4397.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 651.4;intermediate monocyte: 544.6;myeloid DC: 397.8;non-classical monocyte: 441.2;T-reg: 251.9" "Group enriched" "Detected in all" 13 "dendritic cells: 397.8;monocytes: 651.4;T-cells: 251.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 1169.3;CAPAN-2: 968.0;OE19: 1613.0;SK-MEL-30: 2329.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003162, CAB005191, HPA076528" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1900000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005191: AB_2136784, HPA003162: AB_1078937, HPA076528: " "unprognostic (1.42e-1)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" "unprognostic (3.15e-1)" "unprognostic (2.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.73e-3)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-3)" "unprognostic (5.97e-2)" "unprognostic (8.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.96e-2)" "unprognostic (2.65e-3)" "unprognostic (7.60e-3)" 404.5 72.0 111.4 219.8 111.8 346.9 323.1 110.7 148.1 331.4 104.3 1194.1 691.9 162.3 53.8 437.8 223.1 273.0 246.2 110.3 109.4 120.0 27.3 356.1 84.5 118.6 111.9 251.4 79.9 19.8 60.6 141.2 108.6 143.1 875.4 68.3 358.6 177.4 78.6 473.1 853.4 158.8 110.4 61.9 340.7 63.5 125.2 53.0 72.3 105.6 114.1 300.8 273.5 114.0 298.6 96.5 3.3 2.5 581.2 1169.3 344.9 226.7 496.2 64.0 113.2 225.4 968.0 0.7 121.3 272.8 114.6 289.0 6.1 245.4 37.5 357.1 4.4 1.0 104.7 103.8 446.8 1.0 1.1 363.4 375.2 73.9 152.8 145.1 101.5 0.7 1.4 283.1 148.8 218.5 1.3 74.4 5.6 1613.0 271.1 0.7 11.3 22.4 604.8 434.2 7.8 22.6 529.0 0.9 2329.1 16.2 242.8 31.4 180.5 297.8 41.5 112.0 4.4 154.0 535.6 2.8 426.8 18.6 31.8 18.5 651.4 32.4 15.7 544.6 99.7 11.5 58.4 44.2 397.8 4.7 2.5 8.3 28.7 24.2 441.2 9.6 251.9 449.6 111.4 111.8 110.7 148.1 110.3 109.4 118.6 111.9 108.6 110.4 125.2 114.0 1157.4 721.1 359.8 33.3 42.0 631.3 624.1 1278.9 241.9 2.9 307.3 478.7 218.2 258.7 1463.3 119.5 0.0 766.1 38.8 4097.0 673.1 605.9 21.7 636.2 742.7 397.8 173.4 578.1 0.2 1057.8 1051.7 666.3 281.4 846.8 580.5 6.3 64.6 2.3 1137.4 1.7 0.5 1733.8 1778.1 287.8 844.6 44.4 555.7 651.2 848.4 14.0 639.1 300.1 9.2 2.0 0.3 1289.6 3445.9 384.0 77.4 708.4 4397.2 81.3 1506.5 14.7 144.7 220.2 521.0 11.5 6.6 524.8 797.6 483.8 119.5 2.9 1880.1 1139.7 LHFPL2 KIAA0206 ENSG00000145685 "LHFPL tetraspan subfamily member 2" Q6ZUX7 5 78485215-78770021 "Predicted membrane proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 121.9;Microglial cells: 209.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.9;plasmacytoid DC: 6.3" "Group enriched" "Detected in many" 9 "dendritic cells: 6.3;granulocytes: 7.9;monocytes: 3.9" "Cell line enhanced" "Detected in many" "GAMG: 116.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042402, HPA076743" Uncertain Approved "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA042402: AB_10794276, HPA076743: " "unprognostic (2.19e-2)" "unprognostic (3.86e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (4.45e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (3.44e-3)" "unprognostic (2.32e-1)" "unprognostic (8.43e-2)" "unprognostic (3.62e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.45e-7)" "unprognostic (3.40e-2)" "unprognostic (3.88e-2)" "unprognostic (1.34e-2)" "unprognostic (7.85e-2)" 18.2 18.8 10.9 19.6 11.5 18.4 20.5 12.0 13.4 14.0 15.3 17.7 23.8 18.0 18.9 6.3 9.1 22.6 12.2 10.1 11.1 3.1 6.4 19.7 15.2 17.2 13.7 18.5 11.4 10.4 5.7 14.8 14.9 11.4 17.5 5.5 19.3 24.7 2.7 5.7 21.2 22.0 14.6 4.3 14.8 9.1 18.5 14.8 9.1 4.1 14.4 36.3 10.3 18.7 9.8 36.1 10.6 14.1 63.0 18.0 32.7 11.0 28.0 18.7 32.5 12.8 28.4 24.4 4.8 21.7 116.4 16.6 10.2 11.8 30.6 0.2 9.1 24.3 7.2 21.6 46.5 0.1 0.2 20.7 46.6 57.3 88.4 29.6 44.8 0.9 0.2 17.8 42.9 5.2 0.1 1.4 11.8 7.9 10.3 4.7 15.0 6.8 7.1 42.6 2.0 14.4 17.9 6.6 62.5 22.3 3.9 3.0 29.8 21.7 11.8 60.1 33.2 0.7 0.1 34.1 57.5 0.2 39.7 7.9 3.9 4.0 0.0 1.4 0.1 0.6 0.0 0.0 0.9 0.6 0.0 0.0 0.7 0.0 0.5 6.3 0.1 1.3 10.9 11.5 12.0 13.4 10.1 11.1 17.2 13.7 14.9 14.6 18.5 18.7 13.5 3.2 3.4 20.2 5.7 8.7 7.3 5.2 0.6 6.6 18.2 15.6 3.7 1.5 7.6 7.3 0.0 4.0 20.3 34.8 0.0 9.1 1.5 7.5 26.3 21.4 2.4 10.7 15.8 12.9 2.6 38.1 10.7 14.6 0.0 121.9 35.3 1.4 60.1 3.3 7.9 16.3 6.1 40.4 14.7 1.7 19.3 36.3 10.6 209.9 5.5 5.4 0.0 55.3 4.6 17.0 16.1 33.4 3.3 10.4 29.8 0.7 3.9 2.2 6.6 19.1 13.1 0.7 1.7 1.4 4.8 7.3 1.3 22.1 10.0 12.4 LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401514-42427388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 834.5;breast: 524.7" "Cell type enhanced" "Detected in many" "Adipocytes: 76.1;Early spermatids: 127.8;Late spermatids: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "ASC diff: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006567, CAB017700" Enhanced Supported Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017700: AB_2135504, HPA006567: AB_2667618" "unprognostic (4.24e-2)" "unprognostic (2.46e-2)" "unprognostic (8.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-3)" "unprognostic (5.68e-2)" "unprognostic (2.84e-1)" "unprognostic (3.11e-1)" "unprognostic (9.44e-2)" "prognostic favorable (1.15e-4)" "unprognostic (1.52e-1)" "unprognostic (3.63e-10)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.76e-2)" "unprognostic (2.34e-3)" 834.5 45.1 22.7 7.7 71.7 5.0 524.7 77.2 41.5 5.1 0.6 10.9 5.3 6.4 1.2 8.6 5.8 3.7 32.5 23.8 42.6 7.7 1.5 3.7 7.3 100.3 73.9 4.9 6.2 4.7 6.9 2.9 90.0 7.1 1.4 2.0 17.2 2.6 19.7 23.6 24.4 2.6 44.0 14.4 8.5 68.6 57.1 6.9 9.6 23.3 3.7 14.2 7.7 116.9 12.7 9.6 6.0 2.3 136.8 1.3 0.1 5.8 3.1 9.2 8.5 2.3 4.6 20.6 6.3 1.8 4.5 5.6 3.7 11.5 1.0 4.0 6.1 5.8 5.3 0.2 2.7 0.1 13.9 1.2 10.7 1.5 2.1 1.3 2.6 8.5 2.7 12.8 1.2 0.1 14.8 0.5 0.8 9.7 2.7 12.2 1.1 6.9 2.6 13.1 8.5 8.8 5.1 5.7 5.6 0.3 1.5 7.5 4.7 2.5 7.8 1.1 5.3 9.7 8.5 15.6 6.3 0.7 8.7 11.0 8.6 3.8 2.5 4.7 2.3 3.4 3.2 3.7 3.6 4.5 2.8 2.5 1.5 3.6 2.7 2.9 3.0 3.1 22.7 71.7 77.2 41.5 23.8 42.6 100.3 73.9 90.0 44.0 57.1 116.9 76.1 0.0 3.3 4.2 8.1 4.1 12.1 2.4 4.6 11.0 4.8 2.9 2.5 0.0 2.0 1.8 10.4 0.1 4.8 1.3 1.9 8.0 127.8 0.9 3.4 10.2 0.0 5.3 4.6 2.7 0.1 2.0 3.6 1.5 0.0 6.6 17.9 0.0 0.6 8.4 6.7 2.0 6.1 2.2 2.4 236.5 3.1 0.8 5.4 4.7 0.9 4.0 6.2 6.0 37.9 1.8 0.7 1.5 3.0 6.7 18.4 1.5 0.8 13.9 0.0 7.2 2.1 39.4 13.1 2.5 2.4 0.0 5.1 5.2 2.9 10.7 LMNB1 ENSG00000113368 "Lamin B1" P20700 5 126776623-126837020 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.0;lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "Early spermatids: 92.5;Erythroid cells: 67.3;Extravillous trophoblasts: 68.2;granulocytes: 93.6;Late spermatids: 72.1;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005269, HPA050524, CAB079757, CAB079954" Supported Supported "Nuclear membrane" NA NA 2100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "CAB005269: AB_648156, CAB079757: AB_2665863, CAB079954: , HPA050524: AB_2681156" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" "unprognostic (4.96e-3)" "unprognostic (3.70e-2)" "unprognostic (1.61e-1)" "unprognostic (8.65e-3)" "prognostic unfavorable (3.08e-6)" "unprognostic (2.06e-2)" "unprognostic (6.62e-3)" "unprognostic (5.28e-2)" "unprognostic (2.13e-3)" "unprognostic (2.33e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.33e-2)" "unprognostic (2.06e-1)" "unprognostic (1.08e-1)" "unprognostic (2.55e-1)" 4.2 1.6 1.9 26.6 1.8 34.0 2.9 9.8 2.1 3.7 0.5 14.9 11.2 2.8 0.5 14.2 1.8 3.4 1.5 1.6 3.3 3.5 4.9 6.0 34.8 2.9 2.3 2.2 2.4 0.7 2.0 6.7 2.4 1.6 13.0 6.4 3.4 1.6 1.0 8.6 14.2 3.5 2.1 13.3 7.9 2.2 2.3 49.2 1.6 1.4 29.2 6.8 4.8 1.8 132.7 43.4 131.6 126.6 3.3 9.3 170.6 60.6 17.8 66.1 71.3 113.4 107.2 229.4 103.2 21.4 31.5 72.4 90.9 42.1 72.2 162.9 112.1 147.5 49.1 67.2 1.4 176.6 95.6 3.0 0.9 35.2 16.0 12.8 54.9 92.0 87.1 86.3 46.6 109.7 322.8 347.5 99.0 54.1 60.0 152.6 259.4 93.1 36.6 59.6 151.4 80.3 98.4 41.7 36.6 45.2 76.2 202.0 46.9 48.7 132.0 36.6 131.3 56.8 46.4 197.3 25.0 247.1 73.8 1.4 14.4 4.8 2.1 5.6 1.6 4.2 4.3 2.8 15.3 2.9 3.1 2.8 9.3 2.4 1.5 4.6 12.4 6.4 1.9 1.8 9.8 2.1 1.6 3.3 2.9 2.3 2.4 2.1 2.3 1.8 3.4 0.0 4.3 0.3 20.1 5.0 1.9 2.0 8.0 6.4 4.3 5.1 1.6 4.3 3.3 0.0 8.4 39.4 56.0 7.7 1.9 1.8 92.5 3.9 4.8 8.8 6.1 67.3 6.8 0.8 68.2 8.1 11.7 7.6 93.6 23.9 3.6 3.1 21.8 5.0 9.1 19.3 0.0 13.1 17.9 72.1 2.1 27.9 1.8 1.9 59.5 3.8 13.4 5.5 1.1 1.1 8.4 0.4 50.6 1.1 3.8 2.1 1.9 17.5 0.0 2.5 7.3 3.4 8.9 27.3 5.4 4.7 34.2 3.0 35.8 1.4 LRAT LCA14 ENSG00000121207 "Lecithin retinol acyltransferase" O95237 4 154626945-154753120 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "Acyltransferase, Transferase" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6" "Cell type enriched" "Detected in many" 6 "Granulosa cells: 104.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 11 "NTERA-2: 15.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA070726 Uncertain "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "Endoplasmic reticulum" "HPA070726: " "unprognostic (3.64e-3)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (4.75e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.65e-1)" "unprognostic (9.25e-2)" "unprognostic (1.03e-4)" "unprognostic (4.49e-6)" "unprognostic (6.11e-2)" "unprognostic (1.05e-1)" "unprognostic (3.98e-1)" 0.2 0.2 0.6 0.2 0.7 0.5 0.4 0.7 2.6 0.2 1.6 0.5 1.2 0.1 0.3 0.0 0.2 0.5 0.1 0.7 1.2 0.1 2.1 0.3 0.1 1.0 1.1 0.3 0.8 0.2 0.2 0.1 1.3 0.4 0.1 1.0 0.1 0.5 0.8 0.4 1.6 0.1 0.7 0.1 0.3 0.8 0.7 0.0 1.5 0.0 0.1 0.1 0.1 0.9 0.5 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.3 0.2 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 15.3 0.0 0.0 0.0 0.0 0.1 1.4 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.6 1.9 0.1 0.1 0.6 0.1 0.1 0.1 0.1 1.5 0.2 0.1 0.1 0.8 0.2 0.2 0.2 0.1 2.2 0.6 0.7 0.7 2.6 0.7 1.2 1.0 1.1 1.3 0.7 0.7 0.9 0.2 0.0 4.4 4.6 0.1 1.1 4.4 4.0 0.6 0.5 8.6 9.1 0.3 11.5 1.7 0.0 0.0 0.1 0.3 0.8 3.9 1.2 15.2 0.9 0.5 0.3 0.0 0.0 2.2 0.8 0.1 1.5 2.0 2.2 0.0 104.4 1.4 2.2 0.1 0.0 0.6 0.9 2.0 0.8 2.8 3.2 0.0 0.3 5.4 0.0 0.0 3.9 0.0 1.0 2.2 1.2 0.0 0.0 0.0 2.4 12.3 1.0 0.9 0.8 0.0 1.4 8.1 10.5 4.7 1.4 1.1 0.3 0.6 0.0 1.2 0.6 LRMDA "C10orf11, CDA017, OCA7" ENSG00000148655 "Leucine rich melanocyte differentiation associated" Q9H2I8 10 75431624-76560168 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation Albinism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 61.5;epididymis: 59.5" "Cell type enhanced" "Detected in many" "Adipocytes: 42.4;Distal tubular cells: 33.2;Endometrial ciliated cells: 27.8;Hofbauer cells: 56.9;Proximal tubular cells: 113.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 57.6;eosinophil: 22.1;intermediate monocyte: 28.8;myeloid DC: 67.5;non-classical monocyte: 17.1" "Group enriched" "Detected in many" 7 "dendritic cells: 67.5;granulocytes: 22.1;monocytes: 57.6" "Cell line enhanced" "Detected in many" "Hep G2: 46.3;HMC-1: 34.0;NB-4: 65.6;SK-MEL-30: 93.0;THP-1: 48.7;U-937: 43.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047446, HPA050419" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA047446: AB_2680050, HPA050419: AB_2756316" "unprognostic (1.04e-1)" "unprognostic (8.03e-2)" "unprognostic (2.40e-1)" "unprognostic (7.97e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.31e-1)" "unprognostic (8.57e-3)" "unprognostic (5.86e-2)" "unprognostic (6.80e-2)" "unprognostic (8.34e-2)" "unprognostic (1.26e-1)" "unprognostic (7.34e-3)" "unprognostic (7.26e-2)" "unprognostic (6.50e-2)" "unprognostic (4.98e-3)" "unprognostic (3.64e-2)" 16.1 61.5 8.0 5.4 8.6 27.5 10.3 7.7 7.7 12.0 4.7 8.1 5.8 6.4 59.5 7.5 9.7 10.2 13.3 7.8 8.4 20.6 35.8 12.8 5.2 11.5 9.6 13.0 24.9 20.6 10.1 12.7 11.8 10.7 7.2 2.4 9.2 10.0 2.7 3.1 4.5 9.0 10.2 10.5 16.8 3.7 10.9 4.1 18.6 4.8 5.1 11.4 4.5 11.5 0.3 5.7 0.2 0.1 2.9 3.5 0.1 0.7 0.0 0.3 0.5 7.6 13.4 0.0 25.8 0.0 0.1 0.3 0.0 0.0 0.1 0.5 1.6 1.6 2.9 46.3 1.1 9.4 34.0 1.4 1.0 0.6 0.1 5.5 0.8 0.1 0.0 1.4 0.1 1.0 0.1 65.6 0.3 3.9 2.2 0.1 0.2 0.1 0.6 8.3 0.3 0.4 8.1 0.0 93.0 0.2 0.5 48.7 0.9 0.3 3.1 2.4 5.3 0.4 0.2 0.2 22.6 43.6 11.3 6.4 57.6 22.1 0.1 28.8 0.3 0.1 0.0 0.0 67.5 0.1 0.1 0.1 3.2 7.1 17.1 0.5 0.2 18.9 8.0 8.6 7.7 7.7 7.8 8.4 11.5 9.6 11.8 10.2 10.9 11.5 42.4 22.4 19.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.1 5.7 0.0 0.0 3.7 12.9 0.0 1.1 0.8 0.0 33.2 16.6 0.0 27.8 2.5 13.2 0.0 0.0 0.0 15.8 0.8 4.5 0.0 10.0 7.6 16.1 0.0 0.0 56.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.1 0.0 0.0 113.4 6.6 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 1.2 0.6 25.7 0.0 0.0 LRP1 "A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A" ENSG00000123384 "LDL receptor related protein 1" Q07954 12 57128483-57213361 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Endocytosis "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 109.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 273.4;Hepatocytes: 188.4;Leydig cells: 233.3;Peritubular cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "classical monocyte: 4.3;intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 21 "dendritic cells: 1.6;monocytes: 4.3" "Cell line enhanced" "Detected in many" "ASC diff: 484.8;ASC TERT1: 488.4;fHDF/TERT166: 222.2;HSkMC: 318.5;hTERT-RPE1: 248.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004182, CAB018621, HPA022903" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 180000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB018621: AB_627893, HPA004182: AB_2667163, HPA022903: AB_10602426" "unprognostic (1.65e-1)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (5.00e-2)" "unprognostic (4.33e-2)" "unprognostic (3.98e-1)" "unprognostic (8.68e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-3)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.29e-5)" 109.2 14.1 21.3 29.0 36.3 8.2 40.0 30.2 19.7 32.3 8.0 24.1 23.2 36.9 6.2 19.3 30.3 31.5 35.5 16.7 21.9 5.7 35.0 34.0 4.9 46.0 31.5 71.0 10.7 7.8 10.2 39.8 27.9 13.8 11.2 9.9 20.3 20.2 13.0 20.4 18.4 28.9 27.1 13.6 15.1 7.3 48.9 5.6 17.6 23.5 2.7 25.5 29.3 27.6 7.7 14.5 30.4 24.2 484.8 488.4 91.2 85.3 109.0 27.5 26.7 26.9 12.4 0.4 10.4 222.2 6.0 33.6 5.3 8.7 9.7 0.7 1.3 0.4 17.9 56.4 66.5 0.5 14.6 318.5 3.1 61.8 7.2 248.7 1.7 1.1 0.4 1.3 87.2 1.7 0.2 0.4 34.8 11.0 8.8 3.2 171.0 1.6 1.9 2.2 1.4 16.4 19.0 0.6 13.2 42.0 2.9 1.2 1.2 96.0 35.0 53.9 5.2 1.1 0.1 0.2 167.4 0.1 18.7 0.0 4.3 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 1.6 21.3 36.3 30.2 19.7 16.7 21.9 46.0 31.5 27.9 27.1 48.9 27.6 24.6 12.8 8.4 113.6 3.2 24.0 11.9 28.7 19.9 29.2 4.9 19.3 14.8 15.7 14.7 1.8 0.0 87.5 1.1 81.7 0.0 7.4 1.9 9.7 111.4 13.0 4.2 0.8 39.3 1.8 53.0 273.4 49.5 4.2 6.3 36.9 11.0 188.4 73.8 8.4 41.6 14.1 6.1 145.3 28.6 8.4 233.3 102.9 28.4 89.9 48.8 154.7 1.0 173.4 6.6 14.7 27.2 184.3 4.4 5.5 86.0 2.1 15.1 7.3 39.5 129.7 77.0 1.6 2.4 35.4 16.1 125.9 4.2 11.4 25.0 12.3 LTBR "D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3" ENSG00000111321 "Lymphotoxin beta receptor" P36941 12 6375045-6391571 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 71.3;intermediate monocyte: 66.3;myeloid DC: 49.8;neutrophil: 45.0;non-classical monocyte: 50.1" "Group enriched" "Detected in many" 36 "dendritic cells: 49.8;granulocytes: 45.0;monocytes: 71.3" "Cell line enhanced" "Detected in many" "HHSteC: 393.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026202, HPA061617" Uncertain Supported "Golgi apparatus" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus" "CAB026202: , HPA061617: AB_2732666" "unprognostic (2.60e-2)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.23e-2)" "unprognostic (3.01e-2)" "unprognostic (3.24e-3)" "prognostic unfavorable (5.13e-4)" "unprognostic (2.08e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (3.66e-2)" "unprognostic (9.84e-3)" "unprognostic (6.91e-2)" "unprognostic (2.86e-1)" 67.6 64.4 13.9 36.4 14.6 11.7 60.3 14.7 15.9 65.8 18.0 72.7 48.6 68.1 20.7 81.3 49.6 48.3 37.2 13.3 15.8 55.1 135.8 66.0 14.6 19.6 17.3 46.3 78.7 54.9 26.3 48.6 18.8 61.9 34.3 1.9 61.5 44.0 26.3 75.1 51.1 62.6 17.4 44.8 67.7 13.3 18.1 11.7 57.2 23.5 18.0 65.8 65.1 17.0 98.2 130.3 0.0 41.1 245.9 183.7 89.9 67.9 153.1 98.8 101.1 62.0 148.7 0.1 39.5 145.7 0.5 112.2 0.5 140.5 38.9 0.0 0.2 58.1 53.2 36.6 393.1 4.1 94.6 270.8 255.2 70.7 197.1 102.6 91.2 0.0 55.5 0.5 115.0 93.5 0.4 29.3 1.2 155.7 74.4 0.0 6.6 0.2 149.2 112.2 0.7 0.5 63.6 122.9 143.6 5.0 20.5 105.3 58.0 34.6 39.6 129.0 72.1 0.0 0.4 0.1 14.6 35.9 129.5 5.4 71.3 0.5 0.2 66.3 0.0 0.1 0.1 0.1 49.8 0.1 0.3 0.2 45.0 1.5 50.1 11.8 0.1 27.2 13.9 14.6 14.7 15.9 13.3 15.8 19.6 17.3 18.8 17.4 18.1 17.0 47.0 60.9 68.9 2.9 3.6 39.0 87.2 46.4 72.3 4.1 33.9 35.9 15.5 45.8 60.7 31.3 0.0 31.3 12.4 78.3 9.8 52.2 0.7 23.8 48.6 49.3 52.0 15.8 0.5 99.8 43.6 50.5 89.7 45.2 29.7 30.1 50.7 66.5 48.7 0.0 0.5 57.1 34.6 77.3 34.6 5.1 52.8 50.8 23.2 14.0 43.1 9.6 11.3 5.5 1.1 69.5 82.3 39.9 3.3 110.7 136.9 30.1 42.8 1.6 26.3 33.1 42.0 1.6 0.9 78.9 61.7 37.5 4.9 28.0 63.4 97.6 LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10588.1;salivary gland: 21115.5;stomach 1: 8941.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3106.1;Kupffer cells: 2841.2;Langerhans cells: 4859.1;Macrophages: 4870.7;monocytes: 7063.0;Pancreatic endocrine cells: 3152.5" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25266.2;myeloid DC: 14438.7" "Group enriched" "Detected in all" 20 "dendritic cells: 14438.7;monocytes: 25266.2" "Cell line enriched" "Detected in many" 13 "OE19: 12130.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 1500000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" 95.8 27.8 3.5 802.1 4.0 10588.1 128.2 3.7 18.5 156.2 11.4 309.0 3605.0 65.7 4.2 106.3 33.9 1054.6 34.8 2.6 4.3 32.4 138.0 1355.2 739.7 8.0 7.3 20.4 63.1 13.8 7.2 91.3 12.2 40.2 273.8 4.4 21115.5 21.8 34.0 58.7 1322.2 123.9 5.4 621.0 8941.1 21.8 10.9 321.8 27.8 36.4 652.8 428.5 16.2 11.7 0.6 0.1 0.0 0.2 0.0 0.0 4.8 0.0 0.0 0.0 0.3 9.5 6.5 4.2 1.5 0.0 3.6 1.2 0.0 0.0 0.2 1.2 0.1 62.4 1.0 960.4 0.0 110.6 50.5 0.0 0.1 0.0 0.0 0.2 0.0 0.3 7.7 0.3 0.0 0.2 2.6 109.5 2.3 12130.8 0.2 1.6 1.4 16.7 0.3 0.5 0.8 3.6 0.5 0.1 0.5 0.7 0.0 489.0 0.6 0.0 2.6 2.3 0.9 2.6 1.1 1.2 0.1 518.5 0.0 443.4 25266.2 298.2 32.6 4798.4 52.3 100.5 20.1 22.7 14438.7 20.8 20.0 17.8 1007.7 108.1 880.1 301.2 31.1 25392.1 3.5 4.0 3.7 18.5 2.6 4.3 8.0 7.3 12.2 5.4 10.9 11.7 24.0 86.6 285.8 0.0 80.8 57.2 1.7 1.2 1.2 0.3 1205.7 32.3 0.2 734.9 51.1 27.6 0.0 5.6 39.6 32.1 0.0 55.1 1.9 2.6 1.9 25.1 12.5 264.6 0.2 547.3 9.4 26.8 3106.1 2.9 123.6 0.5 29.6 25.4 887.1 0.0 0.2 112.4 0.0 2841.2 4859.1 17.4 4.1 4870.7 53.4 0.0 7063.0 0.1 176.1 0.0 0.3 3152.5 600.5 2.2 9.0 2.7 41.8 6.6 33.8 1.0 39.5 7.4 9.9 0.7 3.9 1.5 38.2 8.5 50.6 0.3 111.4 38.3 MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 32.8;Plasma cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 201.8;intermediate monocyte: 178.8;myeloid DC: 158.8;non-classical monocyte: 138.4;plasmacytoid DC: 187.5" "Group enriched" "Detected in all" 5 "dendritic cells: 187.5;monocytes: 201.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" 35.8 21.4 5.3 54.6 6.4 83.6 24.8 6.6 5.9 19.6 18.5 30.3 31.0 21.8 9.0 19.8 19.9 28.4 16.0 4.9 7.4 17.3 23.7 46.8 52.1 10.3 6.7 16.7 39.7 16.6 9.9 24.6 9.5 20.5 22.6 1.6 35.2 14.9 12.1 28.9 33.6 20.2 8.9 70.1 32.7 6.4 9.7 23.1 16.3 9.4 39.3 35.6 16.7 12.4 52.4 26.3 26.4 31.3 85.8 57.3 74.0 37.9 79.2 33.1 32.4 21.3 21.4 56.9 44.9 30.4 9.4 40.1 13.6 25.6 15.7 28.5 41.6 19.8 13.6 34.9 43.5 131.6 130.2 68.5 49.2 18.5 23.3 35.6 31.7 21.1 25.6 41.9 17.8 40.9 17.9 74.2 21.9 26.2 32.8 40.8 36.1 28.8 38.9 59.8 8.2 25.5 37.7 32.0 63.0 15.8 49.4 80.0 42.0 44.8 18.4 44.0 36.2 55.4 65.5 28.0 30.4 127.5 51.2 12.2 201.8 29.7 31.9 178.8 35.4 32.9 28.9 29.0 158.8 26.4 15.4 15.9 29.4 13.2 138.4 187.5 30.7 150.3 5.3 6.4 6.6 5.9 4.9 7.4 10.3 6.7 9.5 8.9 9.7 12.4 1.6 6.4 7.5 8.5 25.1 3.6 2.0 2.7 14.2 2.6 1.9 1.0 0.9 2.8 2.0 1.8 0.0 2.5 20.5 2.0 1.9 1.7 3.7 1.4 2.5 3.1 1.8 9.4 7.8 2.3 2.8 7.2 20.9 1.3 1.3 3.4 1.8 0.8 8.4 0.0 6.4 0.9 0.0 15.4 24.7 11.1 3.7 32.8 1.8 17.8 11.0 1.5 9.2 3.5 13.4 1.5 2.5 4.5 78.1 2.5 3.8 1.5 3.9 4.0 13.1 2.3 2.0 0.6 1.6 11.5 3.3 2.7 9.4 2.7 2.0 2.0 MARVELD1 "bA548K23.8, FLJ22343, FLJ23440, GB14, MGC4415, MRVLDC1" ENSG00000155254 "MARVEL domain containing 1" Q9BSK0 10 97713173-97718150 "Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.2;intermediate monocyte: 2.7;myeloid DC: 3.1" "Group enriched" "Detected in many" 18 "dendritic cells: 3.1;monocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 141.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (3.28e-2)" "unprognostic (2.11e-2)" "unprognostic (1.26e-3)" "unprognostic (3.05e-2)" "unprognostic (1.36e-3)" "unprognostic (8.82e-2)" "unprognostic (7.40e-3)" "prognostic unfavorable (5.85e-5)" "unprognostic (1.54e-2)" "unprognostic (7.44e-3)" "unprognostic (3.40e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (8.89e-7)" "unprognostic (3.92e-3)" "unprognostic (7.02e-2)" "unprognostic (1.50e-1)" "unprognostic (3.86e-3)" 35.9 8.9 4.7 12.6 5.4 5.2 26.7 4.5 5.5 56.8 24.5 57.1 7.7 60.0 16.7 19.7 48.1 20.4 24.8 4.6 7.5 12.4 5.6 29.7 6.9 6.4 5.7 40.5 7.0 11.3 20.0 25.0 5.5 44.3 24.5 2.0 19.1 48.5 6.1 30.8 22.3 47.7 5.8 16.0 23.7 6.8 6.6 5.3 15.9 7.0 6.0 46.5 41.3 5.9 42.0 30.7 26.1 99.9 97.8 94.0 27.0 56.4 141.3 51.6 34.5 13.5 70.4 0.0 44.5 105.1 7.3 50.3 22.4 53.5 25.9 3.2 28.0 20.3 24.6 0.0 40.9 28.6 0.0 82.7 137.5 33.2 38.3 95.3 65.0 17.6 5.7 0.1 57.7 24.1 3.8 9.9 19.5 4.5 30.6 26.1 22.4 7.0 27.4 8.9 16.9 17.8 34.0 0.3 59.7 16.0 13.4 33.7 65.8 51.9 21.2 50.7 21.4 0.0 3.1 0.1 26.5 0.1 40.2 0.0 3.2 0.0 0.0 2.7 0.1 0.0 0.0 0.1 3.1 0.0 0.0 0.1 0.0 0.0 0.7 0.8 0.0 1.0 4.7 5.4 4.5 5.5 4.6 7.5 6.4 5.7 5.5 5.8 6.6 5.9 7.0 9.6 6.3 10.7 0.9 7.6 31.4 13.4 9.6 2.5 7.1 21.0 4.4 11.5 5.7 12.9 6.2 10.5 0.1 31.9 0.0 8.3 0.7 3.1 32.3 10.5 3.0 4.6 2.3 0.9 21.0 29.9 2.0 6.3 2.5 86.6 12.8 0.6 12.9 0.0 2.8 28.9 4.1 32.6 13.4 2.9 23.0 15.6 12.4 7.5 11.7 13.7 0.0 2.5 0.6 1.9 7.0 38.7 0.3 4.0 2.0 0.2 0.7 3.2 0.0 10.0 31.9 0.3 1.6 1.0 5.4 3.4 1.2 13.1 9.4 6.9 MCEMP1 "C19orf59, MGC132456" ENSG00000183019 "Mast cell expressed membrane protein 1" Q8IX19 19 7676628-7679826 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 65.9;lung: 74.2;lymphoid tissue: 35.1" "Cell type enriched" "Detected in some" 4 "Macrophages: 147.5" "Cancer enhanced" "Detected in many" "lung cancer: 3.7" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Group enriched" "Detected in some" 5 "classical monocyte: 102.1;neutrophil: 45.9" "Group enriched" "Detected in many" 5 "granulocytes: 45.9;monocytes: 102.1" "Group enriched" "Detected in some" 6 "THP-1: 53.7;U-937: 166.6" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected" "Not detected" HPA014731 Enhanced Supported "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA014731: AB_1845619" "unprognostic (4.84e-2)" "unprognostic (9.81e-4)" "unprognostic (2.41e-1)" "unprognostic (4.36e-2)" "unprognostic (8.85e-3)" "unprognostic (2.62e-3)" "unprognostic (5.57e-3)" "unprognostic (1.42e-1)" "unprognostic (2.19e-1)" "unprognostic (4.36e-2)" "unprognostic (1.77e-2)" "unprognostic (3.50e-1)" "unprognostic (2.69e-5)" "unprognostic (1.15e-2)" "unprognostic (7.37e-2)" "unprognostic (1.93e-2)" "unprognostic (7.95e-2)" 4.0 0.5 0.0 19.7 0.0 65.9 0.5 0.0 2.1 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.7 0.6 1.3 0.0 0.0 0.7 1.5 74.2 0.1 0.0 0.0 0.2 0.7 0.0 0.2 1.8 0.9 0.5 0.1 0.0 0.8 0.0 0.3 0.1 0.6 5.1 0.0 35.1 0.9 0.2 0.7 0.9 0.4 1.5 0.1 4.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 1.4 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 53.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 166.6 0.0 0.0 102.1 2.8 0.2 6.0 0.0 0.0 0.3 0.0 14.9 0.0 0.0 0.3 45.9 0.6 0.4 0.9 0.2 38.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.9 0.0 0.7 0.0 0.4 19.2 34.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 11.2 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.0 0.0 2.2 0.0 3.6 0.0 0.0 1.0 2.9 0.0 0.0 7.6 0.0 0.0 0.3 28.8 0.0 0.0 0.0 0.0 28.3 0.0 0.1 0.0 147.5 0.0 0.0 26.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.2 5.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.8 2.9 0.0 0.0 0.1 MFSD2A "FLJ14490, MFSD2" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 96.9;liver: 162.0;skin 1: 87.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 136.2;Hepatocytes: 299.6;Proximal enterocytes: 235.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 12 "dendritic cells: 24.3;monocytes: 13.2" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 52.0;THP-1: 169.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Plasma membrane, Cytoplasmic bodies" "HPA043107: AB_10794387" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (6.92e-2)" "unprognostic (2.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (9.26e-2)" "unprognostic (4.11e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.33e-4)" 6.3 1.4 34.0 3.4 31.7 8.4 13.4 34.8 36.0 4.8 22.2 7.2 14.6 8.5 96.9 12.5 3.5 2.3 1.4 30.9 33.4 5.8 162.0 36.1 2.3 38.5 33.8 2.2 0.6 0.7 8.0 17.1 38.6 2.4 5.0 2.6 4.0 79.2 0.5 87.8 32.0 3.5 32.8 1.5 1.9 33.9 37.2 1.6 7.5 0.1 3.6 20.2 14.1 33.1 6.2 2.7 12.5 18.9 8.7 1.6 0.0 5.9 11.2 12.8 15.1 0.8 3.4 38.0 3.4 3.0 8.8 15.0 12.4 21.8 9.8 4.9 6.0 4.6 0.1 0.1 28.8 6.8 21.8 9.7 13.3 52.0 21.5 2.3 3.1 11.5 0.0 9.5 5.7 0.8 10.6 10.4 10.1 21.4 4.7 7.4 18.5 8.7 2.1 17.9 4.4 6.7 4.5 31.7 3.0 1.1 1.5 169.8 2.0 2.7 5.3 9.5 24.9 1.8 3.5 8.5 28.9 26.0 9.2 0.0 13.2 1.4 0.1 6.6 0.2 1.5 0.1 0.2 14.7 0.2 0.0 0.1 0.7 0.2 1.2 24.3 0.0 3.6 34.0 31.7 34.8 36.0 30.9 33.4 38.5 33.8 38.6 32.8 37.2 33.1 0.5 19.2 136.2 3.3 6.3 52.8 21.2 40.0 51.2 2.0 6.3 2.3 0.6 12.8 30.8 16.5 0.0 0.5 5.7 62.2 0.0 3.4 1.0 25.8 5.5 22.9 1.2 5.7 1.5 24.8 7.6 9.7 24.5 61.8 17.2 0.1 7.1 299.6 6.7 0.0 1.3 34.5 12.2 9.8 43.3 2.7 0.6 16.1 0.0 38.4 5.5 38.8 0.0 0.0 1.6 27.2 39.3 0.4 5.0 13.9 235.1 6.1 33.9 2.7 0.0 5.0 3.3 1.0 1.3 49.3 54.8 52.5 3.3 0.1 20.7 26.6 MGST1 "GST12, MGST-I" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1096.9;adrenal gland: 1137.3;liver: 3104.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1205.9;Club cells: 1308.7;Hepatocytes: 4345.6;Proximal tubular cells: 1265.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 170.2;myeloid DC: 123.5" "Group enriched" "Detected in many" 13 "dendritic cells: 123.5;monocytes: 170.2" "Cell line enhanced" "Detected in many" "ASC diff: 5391.4;ASC TERT1: 2078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 19000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favorable (1.97e-4)" "unprognostic (4.19e-1)" 1096.9 1137.3 139.2 76.1 143.9 79.3 574.8 131.4 200.7 69.7 111.9 315.5 128.9 32.7 43.9 195.3 78.4 200.8 135.1 133.9 165.4 392.9 3104.7 177.2 3.5 156.5 155.7 11.4 131.3 0.8 52.6 14.2 166.6 161.2 212.8 7.0 155.3 55.8 25.5 88.8 119.5 44.7 146.4 7.3 131.4 20.2 147.5 14.0 272.3 43.3 7.7 267.9 114.7 132.9 1.4 495.2 115.6 139.4 5391.4 2078.4 1.5 408.5 418.5 220.6 339.1 186.0 838.6 0.4 48.5 535.8 694.2 2.4 317.0 663.5 202.9 1.1 41.4 175.7 256.6 664.8 1252.0 350.4 1.2 1375.9 714.7 671.2 710.5 540.4 393.1 0.1 126.7 0.6 486.3 101.2 0.3 137.0 987.6 0.7 391.2 0.4 69.3 229.3 503.3 982.1 21.8 17.1 645.8 411.8 17.5 630.1 442.5 190.8 248.0 226.1 30.5 447.3 541.1 0.6 1.7 1.5 748.1 538.5 7.1 11.3 170.2 1.8 0.1 26.3 0.5 1.0 0.2 0.1 123.5 0.0 0.1 0.1 5.9 0.2 5.9 34.1 1.1 55.9 139.2 143.9 131.4 200.7 133.9 165.4 156.5 155.7 166.6 146.4 147.5 132.9 39.6 266.0 651.3 130.2 14.0 25.6 130.2 1205.9 91.0 0.0 383.8 262.6 5.1 574.7 1308.7 71.7 0.0 2.9 9.8 288.1 181.9 26.9 25.4 299.9 198.2 19.6 45.6 92.8 4.4 434.1 218.1 404.5 153.9 947.9 34.1 26.3 67.5 4345.6 160.2 0.0 0.5 280.5 740.6 176.4 52.0 17.9 33.2 75.7 39.2 6.5 224.4 1.0 5.2 1.0 0.8 322.7 175.0 113.2 6.0 467.2 209.5 1265.6 526.1 1.3 0.0 11.3 124.3 0.7 2.3 510.3 17.6 7.9 22.1 152.4 534.1 883.3 MILR1 "Allergin-1, C17orf60, MCA-32" ENSG00000271605 "Mast cell immunoglobulin like receptor 1" Q7Z6M3 17 64449037-64468643 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.3" "Cell type enhanced" "Detected in many" "dendritic cells: 40.5;granulocytes: 34.8;Hofbauer cells: 78.5;Kupffer cells: 33.3;Macrophages: 30.1;Microglial cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 85.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 47.4;CAPAN-2: 120.3;Daudi: 60.4;REH: 45.6;U-698: 63.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014347 Enhanced NA NA 50000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "HPA014347: AB_2732408" "unprognostic (8.40e-2)" "unprognostic (9.77e-2)" "unprognostic (9.28e-3)" "unprognostic (3.27e-1)" "unprognostic (1.17e-1)" "unprognostic (1.21e-2)" "unprognostic (1.27e-2)" "unprognostic (1.22e-1)" "unprognostic (3.25e-1)" "unprognostic (3.31e-2)" "unprognostic (5.99e-3)" "unprognostic (4.78e-2)" "prognostic unfavorable (5.07e-6)" "unprognostic (2.51e-2)" "unprognostic (7.12e-3)" "unprognostic (1.09e-1)" "unprognostic (5.99e-2)" 8.4 5.0 3.7 25.3 4.1 17.8 5.0 3.6 5.1 7.3 4.3 4.9 4.7 3.4 4.3 3.0 2.7 8.1 4.7 3.9 4.0 2.7 4.0 9.4 24.3 7.3 5.5 3.0 1.8 1.8 1.8 16.3 6.9 2.8 8.4 0.8 3.4 2.4 1.3 1.8 5.9 8.3 5.5 17.0 3.0 2.4 6.7 4.3 2.7 0.7 21.3 8.9 2.1 9.5 7.2 1.7 0.2 0.3 4.5 47.4 0.6 0.1 5.2 0.9 10.3 0.1 120.3 60.4 2.6 0.5 23.2 1.4 0.0 2.0 3.1 0.0 0.1 1.5 1.2 0.0 1.0 4.0 37.2 4.4 0.3 13.7 2.1 5.8 4.5 0.5 4.4 6.9 29.2 0.0 0.7 8.7 0.4 0.8 8.6 45.6 8.1 27.1 1.8 0.4 0.2 0.1 3.9 0.4 8.2 0.0 0.4 35.0 16.0 0.3 1.5 0.1 2.9 0.4 0.1 63.6 30.3 7.2 0.0 85.0 47.3 2.8 0.9 40.2 0.7 25.9 0.6 0.6 30.6 16.7 0.7 0.8 14.0 1.5 27.8 53.9 0.6 14.5 3.7 4.1 3.6 5.1 3.9 4.0 7.3 5.5 6.9 5.5 6.7 9.5 3.0 0.0 0.5 0.3 7.5 0.5 2.7 2.7 0.6 0.4 3.1 1.9 0.7 1.5 2.1 0.0 0.0 0.7 40.5 1.1 0.0 0.1 0.7 1.4 2.3 2.7 4.9 1.7 0.5 0.0 2.4 6.1 0.5 2.1 34.8 2.8 1.8 0.1 78.5 0.0 0.5 0.7 2.0 33.3 13.9 0.4 4.1 30.1 0.0 43.1 10.1 0.5 4.1 1.5 0.5 0.0 1.4 1.5 1.2 2.4 0.2 0.0 0.2 1.4 0.0 14.9 3.0 0.3 0.4 0.2 1.7 1.2 1.5 0.1 1.9 2.4 MPO ENSG00000005381 Myeloperoxidase P05164 17 58269855-58280935 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "bone marrow: 4023.1" "Cell type enriched" "Detected in some" 30 "Erythroid cells: 87.4" "Cancer enhanced" "Detected in single" "stomach cancer: 1.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 6.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 94 "HL-60: 3517.4;NB-4: 4589.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000059, HPA021147, HPA061464" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" No NA 576000000 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles Nucleoplasm "CAB000059: AB_2335676, HPA021147: AB_1854083, HPA061464: AB_2684531" "unprognostic (1.91e-1)" "unprognostic (9.08e-2)" "unprognostic (4.62e-2)" "unprognostic (2.90e-2)" "unprognostic (2.13e-3)" "unprognostic (2.78e-1)" "unprognostic (3.23e-1)" "unprognostic (2.91e-1)" "unprognostic (2.56e-1)" "unprognostic (1.68e-1)" "unprognostic (6.92e-2)" "unprognostic (8.34e-3)" "unprognostic (4.91e-2)" "unprognostic (3.07e-3)" "unprognostic (2.83e-1)" "unprognostic (1.14e-2)" "unprognostic (8.05e-2)" 0.5 0.4 0.8 0.6 0.6 4023.1 0.3 0.6 1.1 0.0 0.3 0.2 0.0 0.2 1.1 0.1 0.1 0.3 1.1 0.8 0.7 0.2 1.8 8.4 1.7 0.9 1.0 0.1 0.1 0.0 1.5 1.4 0.9 0.2 0.2 0.4 66.3 0.1 1.1 4.3 0.2 0.3 0.8 21.7 0.1 0.4 0.8 10.9 0.3 0.3 0.2 0.5 0.1 0.7 0.4 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 3517.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4589.9 0.0 0.0 0.0 5.3 3.2 0.6 0.0 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 4.0 0.0 0.0 6.2 0.0 0.0 3.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.4 0.0 0.6 0.0 0.1 7.5 0.8 0.6 0.6 1.1 0.8 0.7 0.9 1.0 0.9 0.8 0.8 0.7 0.0 0.0 0.5 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.9 0.0 0.5 0.1 0.0 0.1 0.0 87.4 0.3 0.2 0.9 0.7 0.0 0.0 0.0 0.0 0.7 0.3 0.9 0.0 0.2 0.0 0.0 1.2 0.0 1.3 0.0 2.9 0.0 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.1 0.3 0.1 0.0 0.1 0.6 0.0 0.0 0.0 MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 580.8;Hofbauer cells: 376.8;Kupffer cells: 1649.6;Langerhans cells: 470.0;Macrophages: 675.9;monocytes: 429.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cell line enriched" "Detected in some" 8 "THP-1: 47.9" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" 72.6 42.3 10.7 57.5 10.9 33.5 40.0 10.8 22.5 28.1 14.7 41.0 27.8 14.3 9.6 25.7 16.8 61.4 22.8 10.0 11.8 11.5 108.6 56.4 109.1 15.8 13.7 12.3 7.8 8.7 9.8 65.2 14.8 12.4 54.9 1.4 16.0 18.3 5.3 7.3 45.1 52.6 12.4 121.5 24.5 7.8 13.6 32.2 10.0 17.7 47.6 59.9 8.6 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.1 0.0 406.4 1095.3 8.2 1.6 345.6 3.4 9.6 2.2 1.4 638.8 1.5 1.0 1.0 72.8 2.1 24.4 454.4 1.9 752.8 10.7 10.9 10.8 22.5 10.0 11.8 15.8 13.7 14.8 12.4 13.6 17.6 5.3 6.4 22.9 0.0 16.1 9.3 0.6 0.0 1.2 0.3 2.2 8.0 3.3 17.2 2.5 3.7 0.0 2.0 220.6 0.3 0.0 0.0 2.2 0.4 0.2 12.8 0.0 43.9 0.1 0.0 2.7 4.3 2.6 0.2 13.9 0.1 580.8 20.5 376.8 0.0 0.1 0.1 0.0 1649.6 470.0 5.1 1.5 675.9 14.2 40.3 429.2 0.0 11.3 0.5 0.1 0.0 1.2 0.0 2.0 0.2 0.0 0.5 1.5 0.6 46.0 3.0 4.4 0.5 1.1 2.4 8.0 2.1 10.4 0.1 0.2 0.3 MTMR14 "C3orf29, FLJ22405, FLJ90311, hEDTP, hJumpy" ENSG00000163719 "Myotubularin related protein 14" Q8NCE2 3 9649433-9702393 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054063 Approved "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "HPA054063: AB_2682365" "unprognostic (9.50e-2)" "unprognostic (5.60e-3)" "unprognostic (9.28e-2)" "unprognostic (1.31e-1)" "unprognostic (8.81e-3)" "unprognostic (2.34e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (2.42e-1)" "unprognostic (2.00e-1)" "unprognostic (3.51e-3)" "unprognostic (7.04e-2)" "unprognostic (1.37e-1)" "prognostic favorable (2.74e-4)" "unprognostic (1.25e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-1)" "unprognostic (1.01e-3)" 18.3 18.0 15.7 22.1 16.4 56.0 15.5 15.6 15.7 12.4 28.1 18.5 17.7 12.7 11.2 15.9 13.5 13.4 34.4 14.8 16.3 18.4 19.5 21.6 37.3 16.4 16.0 13.9 11.8 14.9 10.2 20.1 16.8 12.1 18.4 9.2 13.9 10.7 45.3 19.8 17.9 13.4 15.9 27.8 16.5 16.9 16.6 24.4 15.3 35.6 41.6 18.3 12.7 18.8 18.9 29.1 19.1 11.1 25.6 17.1 106.4 15.0 28.6 29.3 33.6 22.1 27.7 38.2 16.0 24.2 37.8 11.3 23.4 34.2 24.7 34.5 32.5 40.0 24.4 31.9 45.6 35.3 70.6 31.9 22.9 36.9 38.4 19.9 33.2 28.6 25.0 34.0 20.5 60.4 26.1 28.9 31.3 28.2 23.8 27.0 23.1 41.1 26.4 32.6 10.2 28.7 16.7 21.6 29.3 26.0 28.9 57.3 26.0 13.7 21.5 24.9 21.5 37.0 63.3 49.6 31.0 44.0 18.2 116.9 139.9 107.1 44.7 148.1 44.5 76.5 43.3 45.5 177.8 63.4 39.6 40.6 87.7 58.0 145.1 97.2 55.5 113.7 15.7 16.4 15.6 15.7 14.8 16.3 16.4 16.0 16.8 15.9 16.6 18.8 19.3 16.0 6.4 21.5 41.7 10.8 12.2 22.6 8.0 0.0 13.2 12.1 23.8 18.6 14.8 9.2 0.0 47.6 34.2 22.0 29.4 38.3 13.8 10.4 10.5 20.0 12.5 24.8 12.2 28.2 39.0 13.0 27.0 19.6 19.7 15.0 26.4 16.7 67.7 0.0 10.3 14.6 22.4 65.3 28.3 12.8 13.1 55.8 12.4 28.1 68.4 0.0 22.6 9.5 19.9 41.9 25.9 13.2 25.0 15.2 33.2 37.3 10.1 0.0 6.6 15.2 14.0 39.0 40.0 14.7 18.0 64.7 27.0 40.5 16.8 12.7 MYCL "bHLHe38, LMYC, MYCL1" ENSG00000116990 "MYCL proto-oncogene, bHLH transcription factor" P12524 1 39895426-39902256 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 67.8;skin 1: 41.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.9;Hepatocytes: 24.3;Intestinal goblet cells: 25.0;monocytes: 27.4;Squamous epithelial cells: 34.2;Urothelial cells: 27.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 28.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 17.3;intermediate monocyte: 8.2;myeloid DC: 18.7;plasmacytoid DC: 22.8" "Group enriched" "Detected in many" 72 "dendritic cells: 22.8;monocytes: 17.3" "Group enriched" "Detected in many" 7 "U-266/70: 444.0;U-266/84: 364.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA063132, HPA074515" Enhanced "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Mitotic chromosome" "HPA063132: AB_2684946, HPA074515: " "unprognostic (7.45e-2)" "unprognostic (6.91e-2)" "unprognostic (7.36e-2)" "unprognostic (1.83e-3)" "unprognostic (1.61e-2)" "unprognostic (2.92e-3)" "unprognostic (6.72e-3)" "prognostic favorable (4.49e-4)" "unprognostic (1.24e-1)" "unprognostic (1.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.12e-1)" "unprognostic (5.01e-3)" "unprognostic (2.75e-2)" "unprognostic (5.21e-2)" "unprognostic (1.53e-2)" "unprognostic (5.80e-2)" 0.8 0.3 1.8 4.7 2.0 0.6 3.3 1.2 2.0 5.2 1.8 6.1 4.8 0.9 7.2 22.1 3.1 1.5 0.5 2.2 1.7 1.5 11.4 3.3 6.4 1.5 1.5 0.3 67.8 0.3 2.9 6.7 1.6 4.2 6.7 0.2 6.4 7.5 0.5 41.5 5.7 1.1 1.9 7.6 6.2 1.3 2.0 6.5 5.3 0.5 9.5 15.9 12.8 1.6 1.2 0.4 14.4 3.5 0.2 0.1 31.8 0.5 0.2 1.0 0.7 0.4 0.8 2.2 1.4 0.1 0.4 3.3 10.4 2.7 0.8 2.0 4.9 0.5 0.3 0.5 0.4 0.3 7.5 1.0 12.1 0.4 1.3 0.2 1.2 5.4 3.2 0.4 0.6 1.2 0.2 0.3 13.4 2.2 0.4 1.3 15.5 2.9 1.1 58.0 2.5 3.1 1.4 2.1 0.8 5.5 3.7 18.7 0.0 0.0 4.6 6.2 0.5 444.0 364.6 1.0 0.1 2.3 0.3 0.0 17.3 0.0 0.0 8.2 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.2 0.0 3.4 22.8 0.0 6.7 1.8 2.0 1.2 2.0 2.2 1.7 1.5 1.5 1.6 1.9 2.0 1.6 0.4 0.0 1.1 0.0 0.8 6.6 10.0 2.1 13.1 0.4 3.8 6.0 3.7 0.0 5.5 9.2 0.0 34.9 20.1 13.4 0.0 1.5 0.1 5.1 0.6 0.5 17.3 0.0 0.2 5.8 15.4 0.9 5.1 6.3 0.0 0.0 1.4 24.3 5.1 0.0 0.3 25.0 8.2 8.3 13.1 0.4 0.0 10.6 1.8 0.0 27.4 0.8 0.0 1.0 0.0 2.9 6.5 0.0 3.6 5.3 6.4 0.1 4.9 0.1 0.0 1.4 0.7 0.0 1.2 34.2 11.8 17.5 0.3 0.0 10.8 27.1 MYO7A "DFNA11, DFNB2, NSRD2, USH1B" ENSG00000137474 "Myosin VIIA" Q13402 11 77128246-77215241 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Leber congenital amaurosis, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 41.9;choroid plexus: 53.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 47.9;Cytotrophoblasts: 42.3;Hofbauer cells: 30.1;Kupffer cells: 17.8;Rod photoreceptor cells: 31.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.6;intermediate monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 2.6" "Cell line enhanced" "Detected in some" "BEWO: 11.8;CACO-2: 9.0;RH-30: 19.5;RPMI-8226: 13.8;SK-BR-3: 10.5;U-937: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB034059 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "CAB034059: AB_2148626" "unprognostic (1.14e-3)" "unprognostic (2.58e-2)" "unprognostic (2.94e-2)" "unprognostic (1.61e-1)" "unprognostic (9.66e-2)" "unprognostic (4.02e-3)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-1)" "unprognostic (1.32e-1)" "unprognostic (3.65e-2)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.31e-1)" "unprognostic (1.14e-1)" "unprognostic (1.10e-2)" "unprognostic (3.03e-2)" 5.2 41.9 2.5 3.0 2.9 1.0 3.1 2.2 2.7 1.9 53.2 2.8 2.2 1.5 1.2 1.0 2.7 2.8 2.5 4.0 8.6 4.3 23.3 2.3 2.9 5.0 8.3 5.2 5.4 0.5 19.1 16.0 8.4 2.4 1.2 27.4 1.5 0.8 1.4 0.8 2.8 2.2 3.5 15.8 2.2 24.5 5.1 1.4 2.0 0.7 1.1 2.0 1.6 4.4 0.0 1.3 0.2 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 9.0 2.0 0.0 2.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 1.7 0.0 0.3 5.7 0.2 0.4 0.0 0.1 0.0 0.0 0.5 0.0 3.9 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.6 1.2 0.3 0.0 19.5 13.8 0.0 0.3 2.9 0.9 0.1 10.5 0.1 2.2 1.3 1.3 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 2.6 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.8 2.5 2.9 2.2 2.7 4.0 8.6 5.0 8.3 8.4 3.5 5.1 4.4 1.7 0.0 0.0 0.0 0.2 0.3 0.3 0.0 0.0 14.2 0.5 0.5 4.4 4.3 0.0 0.0 47.9 42.3 0.3 0.2 0.0 0.6 1.9 0.1 0.5 2.2 1.2 0.0 0.7 1.7 10.5 1.4 5.6 0.3 0.0 0.8 16.4 16.1 30.1 0.0 0.8 0.7 0.0 17.8 0.9 6.4 3.1 7.3 0.0 6.5 0.8 17.0 0.0 3.0 0.1 0.7 0.2 0.4 0.1 0.1 1.7 2.7 0.1 31.4 0.0 5.2 0.3 0.4 0.6 0.1 0.3 16.1 1.4 3.2 0.6 0.2 N4BP2L1 CG018 ENSG00000139597 "NEDD4 binding protein 2 like 1" Q5TBK1 13 32400723-32428311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 23.8;JURKAT: 22.2;NB-4: 61.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038971, HPA057219" Approved Approved Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA038971: AB_10673408, HPA057219: " "unprognostic (2.66e-3)" "unprognostic (2.38e-3)" "unprognostic (3.63e-2)" "unprognostic (5.32e-2)" "unprognostic (5.09e-2)" "unprognostic (3.40e-2)" "prognostic favorable (3.11e-4)" "unprognostic (6.91e-3)" "unprognostic (2.30e-1)" "unprognostic (9.37e-2)" "unprognostic (2.30e-2)" "unprognostic (1.20e-3)" "unprognostic (4.56e-2)" "unprognostic (1.04e-1)" "unprognostic (2.30e-1)" "unprognostic (3.29e-2)" "unprognostic (2.57e-3)" 24.8 11.9 34.0 14.9 33.8 49.5 26.9 32.9 41.1 23.7 32.3 20.3 15.6 19.5 16.1 11.2 26.3 12.6 12.4 34.2 36.2 15.4 85.6 30.2 26.6 29.0 31.1 45.2 20.3 8.6 37.1 13.5 28.4 21.7 14.6 7.9 12.4 11.6 13.8 27.5 21.1 13.0 28.9 30.1 13.8 4.4 37.2 32.0 17.0 9.7 17.9 16.6 20.5 32.7 0.9 0.3 1.3 0.5 5.0 4.0 0.4 0.6 2.2 1.2 2.0 3.8 5.1 10.3 1.4 1.1 3.7 0.1 3.7 0.3 1.6 15.5 2.3 23.8 1.4 11.4 7.8 9.0 1.4 2.8 0.8 1.0 1.0 9.0 0.8 22.2 0.0 18.3 1.0 0.8 18.6 61.4 1.9 0.0 0.5 17.5 0.6 8.8 4.9 1.8 3.4 4.2 3.7 0.1 1.7 2.4 0.5 16.8 0.4 0.5 0.3 0.3 0.1 10.4 6.6 0.5 0.6 3.4 0.7 59.0 49.3 13.9 18.0 47.2 15.9 28.6 17.5 22.4 43.7 33.0 23.9 20.8 12.5 32.1 34.4 56.0 27.9 36.7 34.0 33.8 32.9 41.1 34.2 36.2 29.0 31.1 28.4 28.9 37.2 32.7 46.1 44.8 27.6 53.2 51.4 30.1 29.6 8.7 23.9 10.6 26.6 22.6 4.3 17.2 16.5 5.5 0.0 22.3 74.8 5.5 9.8 15.0 22.5 23.0 5.7 36.1 37.9 25.5 71.7 8.5 1.1 26.2 6.1 4.8 8.8 16.0 21.0 67.2 22.5 0.0 60.4 9.2 24.4 46.6 102.7 22.7 27.4 54.6 30.2 40.3 110.2 7.2 47.4 72.9 43.4 4.4 12.5 22.2 38.4 24.5 25.8 9.8 8.1 2.2 78.9 48.9 40.4 1.4 2.8 15.2 35.4 10.4 44.0 2.5 12.9 16.5 NAGK GNK ENSG00000124357 "N-acetylglucosamine kinase" Q9UJ70 2 71064344-71079808 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 216.9;Syncytiotrophoblasts: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 391.8;granulocytes: 288.7;monocytes: 594.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035206, HPA035207" Enhanced Approved Nucleoplasm,Cytosol NA NA 1000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol Nucleoplasm "HPA035206: AB_2674517, HPA035207: AB_10602031" "unprognostic (6.15e-2)" "unprognostic (4.23e-3)" "unprognostic (2.97e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (2.44e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.65e-3)" "unprognostic (2.18e-2)" "unprognostic (2.31e-1)" "unprognostic (9.99e-2)" "unprognostic (4.32e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (4.35e-4)" "unprognostic (8.60e-2)" "unprognostic (1.45e-2)" "unprognostic (5.50e-3)" "unprognostic (2.13e-2)" 41.2 36.0 47.0 61.2 48.0 21.9 35.1 49.5 52.1 57.5 47.0 37.7 21.0 33.6 40.6 156.2 29.0 44.1 31.4 46.9 52.9 35.1 42.8 39.6 79.6 50.9 50.4 31.0 42.2 80.7 42.3 44.3 53.7 30.0 34.2 16.5 75.0 37.9 26.6 63.0 33.6 50.1 48.3 88.9 33.9 50.2 49.0 60.8 27.4 32.3 98.4 71.7 59.7 52.1 55.9 39.2 22.6 25.8 114.2 67.5 98.3 119.0 65.5 95.6 86.8 54.3 29.5 30.3 29.3 107.4 113.5 25.7 22.4 43.9 62.7 44.9 16.4 17.0 12.6 37.5 91.6 10.5 37.7 60.7 49.6 101.8 16.4 68.3 107.7 31.7 8.1 34.8 143.4 52.2 28.6 40.2 28.7 53.5 38.4 22.1 64.2 15.8 65.5 91.4 25.1 13.0 35.2 62.1 45.1 50.7 30.4 13.9 66.0 99.0 37.8 36.9 44.8 23.0 24.8 18.0 69.6 31.5 54.5 86.6 594.1 245.1 36.9 526.5 39.2 102.5 44.2 37.0 391.8 103.7 36.7 30.0 288.7 65.3 378.2 318.5 54.7 466.2 47.0 48.0 49.5 52.1 46.9 52.9 50.9 50.4 53.7 48.3 49.0 52.1 22.9 38.5 34.2 15.0 48.6 26.9 28.4 60.8 19.4 46.1 27.4 27.6 18.0 17.2 56.9 38.6 22.9 146.0 67.4 13.9 41.1 66.1 151.3 22.5 26.1 31.7 23.4 12.8 11.5 45.7 144.0 35.6 15.8 24.9 51.9 31.1 30.0 12.9 216.9 47.1 15.2 20.4 28.5 121.8 67.5 33.0 30.1 106.0 39.2 26.2 118.6 45.4 17.5 17.1 24.0 59.1 32.3 37.6 51.2 15.5 23.3 64.7 35.2 55.6 19.7 31.8 37.4 68.0 25.6 39.9 41.6 318.8 29.1 32.2 16.2 34.7 NAIP "BIRC1, NLRB1" ENSG00000249437 "NLR family apoptosis inhibitory protein" Q13075 5 70968166-71025339 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 31.6" "Cell type enhanced" "Detected in many" "Kupffer cells: 138.4;Macrophages: 97.4;Microglial cells: 113.4;Oligodendrocytes: 177.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 8.4;myeloid DC: 5.3" "Group enriched" "Detected in many" 16 "dendritic cells: 5.3;granulocytes: 4.4;monocytes: 8.4" "Cell line enhanced" "Detected in some" "MOLT-4: 3.9;SiHa: 2.1;T-47d: 2.3" HPA042438 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA042438: AB_10796578" "unprognostic (9.03e-2)" "unprognostic (6.03e-2)" "unprognostic (1.31e-1)" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "unprognostic (1.12e-3)" "unprognostic (1.12e-1)" "unprognostic (2.23e-2)" "unprognostic (4.36e-2)" "unprognostic (1.86e-1)" "unprognostic (2.54e-2)" "unprognostic (5.13e-1)" "unprognostic (1.69e-3)" "unprognostic (1.17e-1)" "unprognostic (1.18e-2)" "unprognostic (1.38e-1)" "unprognostic (9.96e-2)" 5.5 2.7 1.1 2.7 0.8 1.6 3.4 1.8 1.7 3.0 1.0 3.2 0.3 2.1 0.8 1.4 4.5 1.1 2.9 1.0 0.8 2.7 3.4 6.8 2.4 0.8 0.5 2.9 3.3 0.2 1.4 0.6 1.0 2.2 0.5 2.1 1.8 0.5 1.0 2.2 4.6 0.8 0.5 31.6 2.8 4.1 1.2 0.4 3.6 0.0 0.2 3.0 2.7 1.0 0.0 0.0 0.6 0.3 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.5 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.4 0.5 0.7 0.1 0.8 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.3 0.4 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.2 0.1 0.4 0.0 2.1 0.0 0.1 0.4 2.3 0.0 0.0 0.6 0.2 0.1 0.0 0.5 0.0 0.3 0.1 0.1 0.4 0.2 8.4 0.0 0.2 2.0 0.1 0.0 0.0 0.1 5.3 0.2 0.2 0.1 4.4 0.3 0.4 0.3 0.1 2.5 1.1 0.8 1.8 1.7 1.0 0.8 0.8 0.5 1.0 0.5 1.2 1.0 8.5 19.2 9.7 60.7 9.4 3.6 2.4 2.2 2.8 16.2 10.2 4.6 3.2 11.5 8.2 5.5 22.9 3.7 7.3 4.1 0.0 1.9 44.0 10.0 15.1 11.1 10.7 18.3 50.2 2.3 2.4 8.2 14.3 10.9 5.1 15.8 9.3 7.3 69.3 16.8 46.4 5.6 2.0 138.4 16.4 11.6 10.8 97.4 1.8 113.4 44.2 6.7 4.1 67.8 177.5 1.6 2.5 7.2 9.8 2.3 1.6 1.3 6.9 38.4 6.6 12.8 5.5 13.7 4.4 3.6 3.8 2.9 8.5 6.0 4.0 1.5 NARS1 NARS ENSG00000134440 "Asparaginyl-tRNA synthetase 1" O43776 18 57600656-57622213 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 221.3;Cytotrophoblasts: 116.0;Extravillous trophoblasts: 85.2;Hofbauer cells: 117.4;Syncytiotrophoblasts: 158.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034257, HPA040017" Enhanced Supported Cytosol NA NA 76000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB034257: AB_2151043, HPA040017: AB_2676801" "unprognostic (9.85e-2)" "unprognostic (1.88e-1)" "unprognostic (3.86e-3)" "unprognostic (1.68e-1)" "unprognostic (2.61e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.23e-7)" "unprognostic (1.78e-1)" "unprognostic (1.48e-1)" "unprognostic (1.62e-2)" "unprognostic (1.98e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.73e-7)" "unprognostic (1.24e-2)" "unprognostic (1.30e-1)" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" 67.2 65.9 51.7 62.1 53.8 48.8 68.3 58.8 77.7 57.5 60.1 108.7 87.3 52.7 66.5 64.2 58.5 56.0 94.8 53.4 60.4 135.1 75.5 51.7 52.8 59.6 55.6 45.4 63.1 125.3 33.2 56.1 58.5 68.4 99.5 68.2 68.8 65.4 127.2 49.6 72.0 65.5 55.9 46.8 79.4 32.7 63.7 59.1 95.0 130.6 67.3 78.0 41.9 60.1 215.1 133.2 129.6 199.1 172.8 130.7 202.5 302.5 161.7 179.2 215.4 100.3 97.0 270.7 136.2 208.7 172.1 241.7 211.0 191.6 259.0 127.5 75.5 217.8 105.4 171.8 299.9 433.0 212.5 146.0 331.2 233.8 245.8 130.6 154.6 169.4 246.5 201.6 200.9 86.2 172.4 111.9 189.6 145.1 118.6 139.8 154.5 229.9 340.3 224.4 140.9 147.6 153.1 184.0 309.4 137.3 108.8 242.6 179.7 190.5 127.7 78.8 215.8 449.1 559.2 260.3 175.1 285.7 227.7 50.9 108.5 38.8 41.8 92.6 50.9 52.6 43.3 44.7 71.7 51.4 58.2 52.6 34.4 43.6 76.8 64.0 49.4 74.9 51.7 53.8 58.8 77.7 53.4 60.4 59.6 55.6 58.5 55.9 63.7 60.1 26.2 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 221.3 0.0 0.0 0.0 0.0 116.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 85.2 23.1 0.0 0.0 0.0 0.0 0.0 0.0 117.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 158.6 3.5 0.0 0.0 0.0 NCEH1 "AADACL1, KIAA1363, NCEH" ENSG00000144959 "Neutral cholesterol ester hydrolase 1" Q6PIU2 3 172630249-172711218 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.2;Pancreatic endocrine cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 287.7;LHCN-M2: 133.1;U-251 MG: 132.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026888, HPA043873" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" No No "Cluster 25: Monocytes - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA026888: AB_10601557, HPA043873: " "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (5.74e-2)" "unprognostic (1.27e-1)" "unprognostic (6.88e-3)" "unprognostic (5.41e-2)" "unprognostic (3.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (5.29e-2)" "unprognostic (2.96e-2)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (2.81e-2)" "unprognostic (2.28e-1)" 3.8 16.2 8.7 8.7 15.8 8.3 5.6 2.3 27.5 4.3 0.0 11.6 4.2 4.6 3.2 3.9 3.4 6.9 14.2 12.5 4.3 21.5 4.9 19.9 14.3 9.3 4.9 1.5 4.7 8.0 3.2 6.7 9.6 6.7 12.0 19.6 10.3 4.4 6.1 1.4 4.8 3.4 3.5 11.2 12.8 1.6 7.8 4.9 4.5 7.4 11.2 8.5 2.1 6.9 98.1 55.3 1.9 3.0 3.3 3.4 7.8 71.8 47.5 46.5 27.2 14.0 287.7 8.1 105.4 43.4 44.4 19.2 2.0 35.1 107.0 27.1 4.5 5.6 8.5 10.8 3.9 14.8 19.9 1.7 3.5 32.3 47.5 43.6 31.5 4.4 1.4 6.9 133.1 8.0 2.5 5.1 2.6 27.4 43.5 2.3 5.2 10.0 83.0 12.6 1.6 0.8 43.6 45.2 9.6 3.1 15.4 6.8 86.9 71.3 10.7 34.1 132.0 8.2 16.4 6.8 53.3 14.1 55.4 6.8 17.9 0.7 2.6 11.6 1.7 3.3 1.6 1.9 12.8 2.2 1.6 2.0 0.6 3.4 7.8 0.7 1.7 6.4 8.7 15.8 2.3 27.5 12.5 4.3 9.3 4.9 9.6 3.5 7.8 6.9 6.6 48.1 17.9 35.9 6.6 6.8 18.3 5.2 1.8 14.8 11.5 3.7 31.6 22.8 20.1 16.5 22.9 9.0 4.7 43.0 3.9 64.1 7.5 41.2 6.4 8.5 7.8 50.5 83.2 31.0 5.2 6.6 25.0 64.1 5.1 5.5 6.8 2.4 49.7 5.0 68.2 11.5 4.1 42.8 15.2 4.1 0.9 32.8 5.4 22.5 12.2 5.4 3.1 15.6 5.4 72.9 13.0 2.6 2.9 30.6 7.3 24.6 27.4 20.5 6.6 8.6 7.0 0.0 1.1 4.3 3.4 10.5 4.6 9.3 7.8 27.3 NDUFB1 "CI-MNLL, MNLL" ENSG00000183648 "NADH:ubiquinone oxidoreductase subunit B1" O75438 14 92116122-92121917 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2435.4;Hepatocytes: 1690.0;Proximal tubular cells: 1614.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063737 Supported Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "Nuclear speckles" "HPA063737: AB_2685109" "unprognostic (1.12e-2)" "unprognostic (1.31e-3)" "unprognostic (6.70e-2)" "unprognostic (2.67e-2)" "unprognostic (1.28e-1)" "unprognostic (2.54e-2)" "unprognostic (6.91e-2)" "unprognostic (3.74e-3)" "unprognostic (5.35e-3)" "unprognostic (4.55e-3)" "unprognostic (1.18e-2)" "unprognostic (4.15e-2)" "prognostic favorable (1.31e-5)" "unprognostic (7.35e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.05e-3)" 260.8 396.4 370.4 109.0 381.4 167.4 231.8 388.5 588.6 178.3 409.2 313.4 165.7 164.9 178.3 281.5 177.1 61.2 1221.5 381.0 401.1 512.7 503.2 182.3 118.4 379.8 374.6 162.7 206.3 373.5 314.7 61.1 383.2 221.5 122.4 260.9 233.5 59.5 862.6 153.6 225.9 69.4 381.2 214.0 292.4 112.3 376.4 230.6 250.4 1053.8 106.1 192.1 202.4 391.0 198.3 388.3 332.5 208.4 219.1 160.7 143.0 243.2 143.7 147.5 135.4 236.9 341.0 187.0 215.7 151.3 205.8 249.6 198.4 212.3 133.9 280.8 425.1 361.3 665.8 308.5 178.2 290.4 196.4 202.5 132.0 159.5 140.7 334.8 136.7 353.7 199.0 370.1 211.8 759.0 286.6 250.0 166.4 779.6 492.1 253.3 309.7 274.2 397.7 491.3 210.8 152.8 486.6 289.7 338.3 277.7 432.0 435.0 291.8 89.3 173.0 181.3 161.7 288.4 477.2 422.0 278.4 208.5 187.9 456.1 566.8 447.5 247.4 409.6 288.5 373.7 361.5 286.0 508.6 306.8 355.4 343.9 721.3 296.6 386.6 604.6 438.9 653.6 370.4 381.4 388.5 588.6 381.0 401.1 379.8 374.6 383.2 381.2 376.4 391.0 158.5 166.7 227.4 11.4 187.4 128.7 102.1 334.5 96.8 84.6 328.2 353.6 2435.4 467.5 237.0 389.9 39.6 260.3 170.4 627.2 1166.1 245.4 175.8 326.0 208.6 188.2 317.4 256.1 18.4 427.7 118.8 203.6 189.6 225.8 215.8 96.2 397.3 1690.0 422.3 55.5 21.7 515.9 268.5 619.8 179.3 57.3 262.5 281.7 332.6 10.3 478.1 223.3 241.0 11.1 15.0 294.4 628.7 241.1 201.6 97.9 845.2 1614.3 337.6 183.3 223.5 172.4 188.2 138.8 151.5 204.5 176.2 205.8 163.7 97.4 540.6 116.3 NEK3 "HSPK36, MGC29949" ENSG00000136098 "NIMA related kinase 3" P51956 13 52132639-52159861 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 87.0;Spermatocytes: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019062, HPA043230" Enhanced Approved Microtubules NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" Microtubules "HPA019062: AB_2670037, HPA043230: AB_2678374" "unprognostic (8.97e-2)" "unprognostic (2.54e-2)" "unprognostic (8.12e-2)" "unprognostic (1.84e-1)" "unprognostic (2.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.31e-1)" "unprognostic (1.31e-1)" "unprognostic (4.30e-3)" "unprognostic (1.16e-3)" "unprognostic (1.70e-2)" "unprognostic (1.17e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (4.15e-2)" "unprognostic (5.34e-2)" 12.4 3.8 13.7 6.2 18.5 8.6 10.6 12.5 21.8 10.8 11.2 16.2 9.3 9.9 6.9 4.2 8.7 7.4 7.8 12.9 14.2 10.1 7.3 9.0 5.0 18.2 17.8 8.2 8.3 3.8 5.2 17.4 17.3 8.2 16.8 4.7 7.0 5.0 6.0 7.2 12.7 8.6 12.9 8.0 6.7 18.1 19.9 3.2 6.3 3.3 5.4 8.3 7.4 26.3 0.3 2.7 20.2 11.4 6.2 10.8 0.3 6.5 6.2 7.6 8.3 8.6 11.1 0.0 0.4 8.4 6.3 1.5 0.4 4.8 4.8 15.1 11.8 1.9 2.7 23.0 7.6 19.4 10.9 7.2 9.5 4.2 17.6 5.6 13.5 1.0 3.1 7.1 9.0 5.1 1.1 23.4 19.7 4.4 0.5 0.5 1.7 7.6 11.4 1.9 2.2 14.0 2.9 6.4 12.8 19.6 2.5 26.3 12.2 1.0 5.9 6.0 6.7 7.5 2.5 13.1 1.8 6.8 10.8 7.1 6.3 5.1 1.6 5.8 1.0 3.6 1.9 1.0 6.7 1.9 1.4 0.4 0.4 1.6 1.2 5.8 2.9 1.4 13.7 18.5 12.5 21.8 12.9 14.2 18.2 17.8 17.3 12.9 19.9 26.3 28.8 6.4 6.5 9.1 5.9 2.8 4.4 2.8 5.7 3.9 5.5 6.7 7.7 5.7 5.8 7.3 0.0 13.0 8.3 20.1 13.7 7.9 11.5 9.8 14.0 22.7 6.0 3.4 0.6 17.3 14.4 8.7 10.2 11.0 10.1 11.6 18.2 7.4 19.1 3.3 3.4 13.7 6.1 12.4 8.1 4.6 7.2 10.4 12.4 18.7 25.4 3.0 7.2 9.0 87.0 15.6 17.9 6.8 6.0 3.3 22.4 6.8 7.1 5.8 0.0 7.1 9.0 49.7 25.5 3.5 3.4 4.8 4.0 3.9 20.1 5.2 NETO2 "FLJ10430, NEOT2" ENSG00000171208 "Neuropilin and tolloid like 2" Q8NC67 16 47077703-47143945 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;lymphoid tissue: 22.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 96.5;Inhibitory neurons: 176.6;Oligodendrocyte precursor cells: 79.4;Theca cells: 98.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013180 Uncertain Approved "Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA013180: AB_1854383" "unprognostic (2.67e-2)" "unprognostic (3.46e-2)" "unprognostic (3.90e-1)" "unprognostic (1.51e-3)" "unprognostic (2.25e-1)" "unprognostic (5.26e-3)" "unprognostic (1.10e-2)" "unprognostic (5.73e-2)" "unprognostic (1.92e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (3.98e-1)" "prognostic unfavorable (5.53e-6)" "unprognostic (3.48e-2)" "unprognostic (1.66e-1)" "unprognostic (6.79e-2)" "unprognostic (1.32e-1)" 2.7 7.2 6.1 6.4 19.8 2.4 2.8 3.6 9.3 1.6 1.0 8.5 1.6 2.2 0.6 6.1 0.8 4.8 2.6 4.1 8.3 2.7 0.7 5.9 6.3 6.9 0.8 1.6 2.5 10.7 1.2 3.4 6.4 1.1 2.4 7.5 2.7 1.2 4.4 1.8 2.8 1.6 1.7 22.7 2.2 8.0 3.5 5.4 8.8 2.2 6.2 4.9 2.9 4.2 86.8 94.4 133.9 0.3 19.3 111.6 22.2 84.0 13.2 72.9 39.3 19.9 54.0 21.3 50.4 18.0 70.2 37.9 86.4 83.6 89.0 0.3 55.7 17.2 32.8 21.3 23.9 55.8 43.7 67.9 54.7 29.5 41.2 70.5 49.2 50.5 25.9 25.7 47.4 23.5 31.9 30.4 64.7 25.8 68.8 0.1 26.2 43.0 51.4 18.3 87.8 63.5 110.9 8.6 12.5 21.8 1.7 40.3 24.1 0.1 0.3 0.1 0.5 27.5 24.7 47.6 58.9 38.9 59.6 0.3 0.9 0.0 0.0 0.5 0.3 0.2 0.3 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.5 0.1 6.1 19.8 3.6 9.3 4.1 8.3 6.9 0.8 6.4 1.7 3.5 4.2 4.9 0.0 4.5 4.6 6.5 7.8 0.6 10.4 13.1 2.2 5.2 8.9 1.3 0.0 3.6 0.0 0.0 1.4 2.1 15.9 0.0 0.4 3.1 2.1 4.0 10.6 10.8 0.4 96.5 3.1 0.5 4.9 1.5 0.9 2.5 18.0 2.9 0.4 6.6 0.0 176.6 2.6 6.1 11.4 14.6 5.7 0.6 16.6 3.6 8.4 7.3 39.9 1.0 79.4 3.1 1.3 1.5 0.0 13.7 4.9 2.9 0.1 2.4 1.6 6.6 5.3 3.6 17.9 22.2 18.8 3.3 0.8 5.2 98.7 2.8 1.4 NFE2L2 NRF2 ENSG00000116044 "Nuclear factor, erythroid 2 like 2" Q16236 2 177227595-177392697 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002990, CAB020317, HPA043438" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane" Cytosol "CAB020317: , HPA002990: AB_1079476, HPA043438: AB_2678482" "unprognostic (2.11e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.41e-1)" "unprognostic (5.95e-2)" "unprognostic (3.90e-1)" "unprognostic (5.27e-2)" "unprognostic (9.58e-2)" "unprognostic (3.48e-2)" "unprognostic (9.86e-2)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "prognostic favorable (2.26e-4)" "unprognostic (1.97e-2)" "unprognostic (1.61e-1)" "unprognostic (1.26e-1)" "unprognostic (9.77e-3)" 87.0 73.6 64.8 65.4 83.9 58.9 78.3 74.9 86.7 83.2 78.7 83.4 100.1 92.6 97.2 257.0 88.5 97.7 77.6 66.5 71.6 143.5 176.6 88.5 50.4 82.0 77.5 137.3 47.3 60.4 58.4 80.4 84.5 72.7 85.8 68.2 79.7 90.5 64.4 162.3 82.9 91.8 70.4 69.0 176.9 65.2 75.7 68.2 130.4 65.9 93.8 160.7 108.7 91.8 53.1 57.3 52.2 56.4 181.4 190.2 61.7 91.8 124.9 81.4 90.5 75.9 97.9 52.8 93.8 102.8 148.4 96.9 65.1 136.7 111.5 40.8 41.1 65.9 95.9 156.3 231.2 39.3 60.6 134.0 314.5 115.5 169.3 184.4 80.9 39.7 72.7 91.4 111.8 49.8 42.3 101.9 58.8 277.2 58.9 34.0 46.5 54.6 120.9 182.1 69.0 45.0 202.9 64.8 216.6 147.8 49.1 105.0 119.9 80.4 54.5 89.5 54.7 70.1 44.7 43.1 81.6 43.3 159.4 130.6 89.3 55.4 55.2 84.3 62.9 61.8 64.0 57.0 100.4 51.9 101.2 66.8 103.2 68.1 83.0 38.8 66.6 66.0 64.8 83.9 74.9 86.7 66.5 71.6 82.0 77.5 84.5 70.4 75.7 91.8 193.3 157.0 93.5 66.3 143.3 295.8 241.8 448.4 306.7 61.3 90.0 113.7 67.9 117.2 247.0 154.5 16.7 113.2 249.1 120.7 393.2 154.5 81.4 238.1 126.9 139.6 75.6 58.0 25.3 170.8 34.5 206.6 170.7 279.9 212.7 141.5 120.0 93.2 88.1 57.2 26.6 73.5 321.4 111.6 569.9 39.0 287.7 266.0 96.0 88.1 170.6 191.4 55.6 63.8 113.0 128.3 91.8 214.0 118.8 150.5 94.9 85.0 205.9 48.4 39.5 211.8 152.4 66.1 32.1 617.9 315.4 186.2 150.6 153.5 119.6 225.2 NIBAN2 "bA356B19.6, C9orf88, DKFZP434H0820, FAM129B, FLJ13518, FLJ22151, FLJ22298, MINERVA" ENSG00000136830 "Niban apoptosis regulator 2" Q96TA1 9 127505339-127578989 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 606.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 73.6;Extravillous trophoblasts: 40.5;Hofbauer cells: 23.0;Syncytiotrophoblasts: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021284, HPA021417, HPA023261, HPA024312" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA021284: AB_1848373, HPA021417: AB_1848374, HPA023261: AB_1848375, HPA024312: AB_1848376" "unprognostic (3.05e-3)" "unprognostic (9.47e-2)" "unprognostic (1.14e-3)" "unprognostic (4.07e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-1)" "unprognostic (3.14e-2)" "unprognostic (2.57e-3)" "unprognostic (1.40e-1)" "unprognostic (1.68e-2)" "unprognostic (1.17e-3)" "unprognostic (6.45e-2)" "unprognostic (3.75e-2)" "unprognostic (1.24e-2)" "unprognostic (1.31e-1)" "unprognostic (8.40e-2)" "unprognostic (8.20e-3)" 48.7 107.5 26.7 36.6 24.7 27.3 42.0 25.2 24.5 96.0 45.3 74.6 50.8 38.9 12.6 606.7 39.4 39.6 39.4 22.7 35.0 72.3 16.7 121.9 6.6 48.9 34.3 31.6 142.6 26.2 34.0 84.8 36.3 66.5 30.3 2.7 142.1 32.2 13.6 111.3 53.9 22.0 39.7 32.2 83.3 11.0 34.7 5.6 110.6 11.3 53.6 68.4 189.6 31.9 134.0 149.8 29.9 39.3 87.9 170.1 138.2 259.1 238.5 140.1 86.4 48.2 143.7 0.4 100.4 295.5 172.9 217.5 25.9 192.2 45.9 25.2 27.5 22.8 218.9 50.4 173.1 1.0 62.0 187.3 118.3 231.4 80.8 256.8 213.6 8.4 43.5 1.2 269.8 157.3 1.6 37.6 30.9 228.0 194.4 16.0 99.9 70.1 120.5 105.6 47.4 22.1 212.3 149.0 93.4 42.1 98.2 7.5 279.9 143.1 62.4 182.2 218.0 2.5 5.1 0.6 403.3 21.6 271.1 0.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 26.7 24.7 25.2 24.5 22.7 35.0 48.9 34.3 36.3 39.7 34.7 31.9 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 73.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 40.5 4.2 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 120.9 0.1 0.0 0.0 0.0 NIPSNAP2 GBAS ENSG00000146729 "Nipsnap homolog 2" O75323 7 55951793-56000181 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 266.5;skeletal muscle: 645.5;tongue: 784.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 226.9;Endometrial ciliated cells: 107.5;Proximal tubular cells: 106.8" "Cancer enhanced" "Detected in all" "glioma: 73.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 301.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063084 Enhanced Supported Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA063084: AB_2684938" "unprognostic (6.88e-2)" "unprognostic (6.53e-3)" "unprognostic (8.20e-3)" "unprognostic (4.95e-2)" "unprognostic (5.79e-2)" "unprognostic (1.53e-3)" "unprognostic (5.95e-3)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" "unprognostic (6.38e-3)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "prognostic favorable (3.02e-8)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (6.65e-3)" "unprognostic (3.59e-1)" 61.2 70.3 46.0 25.4 48.4 39.2 59.0 47.2 56.9 45.4 50.8 56.0 31.4 41.1 36.6 49.0 50.4 27.5 266.5 45.1 49.5 63.8 14.5 36.9 26.4 45.2 48.7 34.7 49.2 70.4 27.1 31.0 47.1 53.4 53.8 27.6 79.2 55.9 645.5 21.9 32.4 46.6 49.0 26.1 46.5 20.5 50.0 40.1 86.5 784.2 28.7 40.8 26.0 47.6 301.3 52.3 67.5 112.6 38.7 65.8 33.1 24.7 58.2 69.7 53.5 36.5 64.9 43.8 40.5 46.6 67.5 39.1 51.4 52.2 68.7 27.9 75.4 31.1 27.6 46.9 54.6 68.0 30.2 60.3 78.4 23.8 64.5 79.1 74.6 62.2 56.2 41.9 54.8 13.4 68.1 70.4 66.7 66.5 52.3 68.0 31.3 90.8 94.6 46.7 71.7 80.8 56.2 67.0 78.3 53.0 129.9 72.3 43.9 31.7 47.4 11.3 52.0 34.1 30.9 81.2 35.1 41.9 95.7 48.2 86.6 39.1 22.6 86.4 27.2 37.7 28.8 23.8 91.7 37.0 34.2 25.2 15.3 41.9 69.1 38.1 37.9 72.4 46.0 48.4 47.2 56.9 45.1 49.5 45.2 48.7 47.1 49.0 50.0 47.6 45.4 51.3 57.7 0.0 10.3 0.0 0.0 0.0 0.0 0.0 80.4 63.8 0.0 0.0 43.3 62.5 0.0 76.0 20.1 0.0 226.9 74.8 0.0 107.5 56.1 22.1 0.0 0.0 0.0 57.2 56.4 23.4 0.0 57.6 16.4 64.7 0.0 0.0 88.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.6 0.0 0.0 39.8 0.0 0.0 0.0 0.0 46.2 0.0 0.0 5.2 0.0 0.0 106.8 88.2 0.0 0.0 0.0 26.7 0.0 0.0 0.0 0.0 51.4 12.3 74.0 0.0 0.0 NOD2 "BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, PSORAS1" ENSG00000167207 "Nucleotide binding oligomerization domain containing 2" Q9HC29 16 50693588-50734041 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.6;esophagus: 11.7;skin 1: 14.4;vagina: 12.3" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 8.3;Kupffer cells: 9.0;Langerhans cells: 22.5;Macrophages: 15.2;monocytes: 15.6;Suprabasal keratinocytes: 15.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 23.0;eosinophil: 6.0;intermediate monocyte: 13.1;myeloid DC: 21.3;neutrophil: 10.5;non-classical monocyte: 9.0" "Group enriched" "Detected in many" 5 "dendritic cells: 21.3;granulocytes: 10.5;monocytes: 23.0" "Cell line enhanced" "Detected in some" "HMC-1: 11.6;T-47d: 5.8;THP-1: 7.3;U-266/70: 15.9;U-266/84: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041985, HPA054494" Enhanced Approved "Golgi apparatus,Cytosol" No NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Cytosol" "HPA041985: AB_2677780, HPA054494: AB_2682505" "unprognostic (1.01e-1)" "unprognostic (4.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.02e-3)" "unprognostic (9.91e-3)" "unprognostic (5.84e-2)" "unprognostic (5.90e-3)" "unprognostic (1.23e-1)" "unprognostic (4.17e-1)" "unprognostic (3.88e-2)" "unprognostic (6.94e-3)" "unprognostic (1.48e-2)" "unprognostic (2.31e-9)" "unprognostic (4.38e-2)" "unprognostic (1.08e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-1)" 1.5 0.5 0.5 5.9 0.2 13.6 1.5 0.2 1.0 5.6 0.7 0.9 1.5 0.6 0.3 11.7 0.9 1.3 0.7 0.2 0.4 0.6 1.7 4.3 2.7 1.0 0.9 0.4 0.3 0.2 0.4 1.2 0.7 0.9 0.9 0.0 4.3 0.4 0.6 14.4 1.3 1.8 0.7 4.4 1.4 0.5 1.4 0.8 0.4 0.3 2.3 1.6 12.3 0.8 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 11.6 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.8 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.1 0.0 1.5 0.0 0.0 5.8 7.3 0.0 0.0 0.0 0.0 0.0 15.9 7.2 0.0 0.3 0.1 0.0 3.0 23.0 6.0 0.4 13.1 0.7 0.1 1.3 1.4 21.3 0.0 0.1 0.5 10.5 3.4 9.0 1.0 0.9 11.1 0.5 0.2 0.2 1.0 0.2 0.4 1.0 0.9 0.7 0.7 1.4 0.8 0.2 0.0 3.7 0.0 1.9 5.9 0.3 1.2 0.0 0.0 1.4 1.1 0.4 1.5 2.3 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 5.6 0.8 0.6 1.2 0.8 0.1 0.0 0.0 0.4 0.0 8.3 1.3 0.5 0.0 0.5 2.5 0.0 0.1 0.0 2.0 9.0 22.5 0.0 0.0 15.2 1.8 1.9 15.6 0.0 1.0 0.0 0.2 0.0 0.0 0.4 4.3 0.4 0.0 0.1 1.0 0.0 0.0 0.1 0.4 0.1 0.4 6.1 15.5 0.3 2.3 0.1 0.1 0.3 NOL3 "ARC, CARD2, MYP, NOP30" ENSG00000140939 "Nucleolar protein 3" O60936 16 67170154-67175735 "Disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "T-47d: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009208 Enhanced Supported Nucleoplasm,Cytosol NA NA 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "CAB009208: AB_634091" "unprognostic (2.83e-2)" "unprognostic (1.63e-2)" "unprognostic (3.34e-3)" "unprognostic (1.07e-1)" "unprognostic (2.70e-3)" "unprognostic (2.83e-1)" "prognostic unfavorable (6.43e-5)" "unprognostic (5.74e-2)" "unprognostic (4.07e-2)" "unprognostic (1.83e-1)" "unprognostic (2.15e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (2.41e-4)" "unprognostic (1.39e-2)" "unprognostic (3.65e-2)" "unprognostic (3.90e-2)" "unprognostic (1.48e-2)" 34.4 77.5 36.1 3.8 37.1 0.7 35.4 36.7 36.2 37.1 30.7 32.5 6.7 27.8 11.4 48.6 35.4 10.2 99.3 32.9 35.0 33.0 52.0 28.9 3.1 43.9 36.2 29.3 50.6 37.7 60.2 11.6 39.6 70.1 7.6 28.6 51.1 13.8 142.2 79.2 18.1 8.0 35.4 15.9 28.2 7.6 36.9 2.8 35.6 97.5 4.1 38.7 39.8 38.1 14.9 23.9 3.9 22.1 19.2 14.5 22.0 11.8 12.5 12.6 7.4 5.2 38.2 0.3 38.0 13.8 3.3 24.3 5.4 18.3 3.0 13.4 8.3 0.6 19.8 7.8 12.0 1.3 2.9 8.9 33.1 9.9 7.0 35.9 5.3 5.2 5.5 15.3 24.0 38.7 0.3 1.9 3.7 13.5 58.1 13.3 8.3 29.8 21.5 4.5 31.1 16.6 49.5 35.3 5.7 5.1 75.5 4.0 12.4 16.5 14.1 16.3 10.3 22.1 7.5 4.2 46.4 3.7 5.7 0.0 3.5 0.0 0.1 0.3 0.0 0.0 1.7 0.1 1.1 0.0 0.0 0.2 0.8 0.4 0.1 1.1 0.0 1.3 36.1 37.1 36.7 36.2 32.9 35.0 43.9 36.2 39.6 35.4 36.9 38.1 5.1 28.9 33.6 19.2 2.7 13.8 27.6 70.6 21.6 18.5 29.3 32.6 51.2 35.8 28.8 3.7 16.7 8.1 0.8 18.2 15.6 61.3 1.2 8.6 14.0 10.1 22.3 0.0 5.0 34.7 11.3 13.8 11.2 16.4 2.5 7.6 13.2 30.9 11.4 55.5 7.6 23.7 38.7 4.1 4.5 0.7 25.1 3.4 21.4 4.7 14.6 36.3 1.0 4.0 11.3 44.2 11.4 30.1 10.4 28.5 15.5 26.2 21.3 47.9 13.1 38.7 32.3 0.3 1.2 16.4 19.7 11.1 3.2 3.6 16.4 31.6 NPLOC4 "FLJ20657, KIAA1499, NPL4" ENSG00000182446 "NPL4 homolog, ubiquitin recognition factor" Q8TAT6 17 81556887-81648465 "Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 164.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 20.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021560, HPA023295" Enhanced Supported Nucleoplasm,Cytosol NA NA 30000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA021560: AB_1854586, HPA023295: AB_1854587" "unprognostic (3.17e-1)" "unprognostic (2.98e-1)" "unprognostic (1.78e-1)" "unprognostic (1.00e-3)" "unprognostic (8.72e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (1.16e-5)" "unprognostic (1.06e-2)" "unprognostic (4.42e-1)" "unprognostic (2.97e-1)" "unprognostic (4.15e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (6.95e-7)" "unprognostic (1.01e-1)" "unprognostic (6.98e-2)" "unprognostic (6.51e-2)" "unprognostic (1.72e-1)" 37.3 46.6 27.2 32.4 27.6 41.7 32.0 22.2 28.3 30.4 27.1 35.2 24.5 35.3 23.5 51.5 28.8 23.3 58.4 26.6 31.2 42.2 54.8 37.9 33.2 31.8 27.2 25.9 36.7 29.7 33.2 27.1 28.5 33.3 21.3 20.1 32.4 22.7 164.3 42.1 34.4 29.3 24.1 42.8 36.8 42.8 28.7 33.4 28.4 55.5 28.8 33.2 31.7 32.8 91.9 118.6 46.2 72.1 56.0 46.0 57.2 74.2 82.3 120.4 110.6 90.7 80.2 67.2 57.9 87.7 87.8 72.5 46.0 62.6 104.5 43.0 60.8 77.5 95.5 81.5 53.4 83.4 95.4 45.8 59.1 113.2 40.1 57.7 124.8 62.0 84.1 99.1 73.6 59.5 113.0 45.2 54.3 45.5 74.0 73.6 73.8 54.4 43.6 86.8 61.6 70.6 92.6 127.4 85.7 87.1 100.1 60.9 89.6 156.1 108.1 86.1 121.4 74.8 57.9 84.0 124.6 55.2 102.9 4.1 20.0 4.4 4.6 4.9 2.8 4.7 3.1 3.7 6.3 3.3 2.8 3.7 5.6 2.8 3.1 4.8 3.2 10.0 27.2 27.6 22.2 28.3 26.6 31.2 31.8 27.2 28.5 24.1 28.7 32.8 19.2 12.8 18.1 24.8 15.3 17.6 16.2 12.7 7.4 24.3 19.5 16.1 44.5 11.5 18.5 20.2 29.2 19.5 22.2 38.9 1.9 19.0 96.2 32.8 19.6 22.2 30.5 20.6 38.0 37.4 21.3 15.9 26.0 38.8 3.8 29.2 27.1 54.3 19.1 20.2 36.4 17.2 8.2 27.3 18.7 79.6 17.7 22.8 12.4 19.7 28.7 19.6 14.4 23.1 38.6 47.2 22.8 12.8 16.5 28.4 22.2 27.9 21.5 33.5 19.7 22.3 18.5 29.7 23.9 15.7 24.2 37.1 16.9 19.3 18.9 28.7 NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Group enriched" "Detected in many" 17 "Excitatory neurons: 1466.4;Inhibitory neurons: 411.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 55.3" "Lineage enriched" "Detected in many" 5 "monocytes: 55.3" "Cell line enhanced" "Detected in many" "A549: 132.5;BJ: 91.3;fHDF/TERT166: 98.1;GAMG: 95.4;U-2197: 84.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA010964: AB_1854641" "unprognostic (5.76e-3)" "unprognostic (8.60e-2)" "unprognostic (1.96e-4)" "unprognostic (2.67e-1)" "unprognostic (1.94e-4)" "unprognostic (4.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" "unprognostic (5.65e-2)" "unprognostic (7.99e-2)" "unprognostic (8.49e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (5.40e-2)" "unprognostic (7.83e-2)" 0.5 1.2 3.5 6.1 3.2 1.4 5.7 8.7 13.2 8.0 3.2 3.2 2.9 1.2 0.6 2.8 1.1 2.3 1.9 0.4 12.7 8.6 17.0 3.7 0.4 35.4 8.0 1.9 0.7 0.6 3.8 0.2 35.3 2.6 3.2 11.6 2.6 1.0 0.1 4.9 2.5 1.0 2.7 1.6 2.5 5.3 2.6 0.8 9.9 0.0 2.1 9.4 3.4 8.2 0.4 132.5 1.8 0.0 0.9 2.5 0.2 91.3 60.0 65.3 55.8 0.0 2.9 0.0 16.4 98.1 95.4 76.7 0.3 34.5 69.4 0.2 0.7 1.3 1.8 2.0 0.4 0.1 0.2 1.3 3.4 81.1 74.6 5.7 41.2 0.1 0.0 0.7 24.4 0.1 0.0 0.1 2.5 0.0 0.0 0.1 0.9 0.0 52.9 3.6 3.4 4.0 7.5 0.0 0.1 5.0 0.0 0.3 34.7 50.7 15.8 84.4 53.6 0.1 0.0 0.9 28.2 0.1 6.6 0.2 55.3 0.9 0.2 4.7 0.2 0.1 0.1 0.0 12.1 0.1 0.0 0.0 2.0 0.2 0.2 0.2 0.0 14.2 3.5 3.2 8.7 13.2 0.4 12.7 35.4 8.0 35.3 2.7 2.6 8.2 0.1 38.5 2.7 29.7 0.8 26.0 48.0 5.1 21.1 11.0 4.3 18.2 2.0 8.6 7.9 3.7 8.4 0.0 1.3 0.0 9.8 1.8 41.5 0.1 1.9 5.7 0.0 0.0 1466.4 0.2 0.0 10.5 0.0 0.2 1.3 3.2 7.1 5.3 0.5 28.6 411.8 0.0 2.0 10.2 1.9 23.5 0.3 22.1 1.8 36.5 49.2 5.0 0.0 54.3 19.2 0.9 0.0 0.4 0.0 42.9 0.0 18.7 2.4 3.1 0.0 0.1 9.3 11.3 5.0 3.2 6.1 0.0 0.6 0.0 0.0 6.5 OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 396.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.9;Fibroblasts: 135.9;Hepatocytes: 218.8;Muller glia cells: 279.4;Theca cells: 149.0;Urothelial cells: 192.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 115.5;Hep G2: 190.1;NB-4: 139.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA047412: AB_10960631" "unprognostic (1.59e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.11e-1)" "unprognostic (3.98e-3)" "unprognostic (5.09e-2)" "unprognostic (3.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.12e-2)" "unprognostic (7.15e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" 66.0 91.5 47.7 18.0 56.8 10.8 42.6 35.8 57.1 66.7 40.5 61.9 47.7 54.2 16.0 22.8 54.6 34.5 55.1 48.1 36.5 51.4 396.6 19.2 5.8 39.0 37.8 61.0 74.1 6.7 27.4 8.1 37.1 33.5 36.5 30.7 53.9 13.7 13.2 12.0 57.3 29.1 35.9 54.4 33.5 3.7 45.0 4.6 25.9 12.2 3.7 42.6 40.4 44.6 24.9 7.5 30.9 14.4 47.8 53.4 1.7 47.7 53.8 20.5 30.0 7.5 37.3 0.0 115.5 35.6 33.7 25.7 8.9 13.2 8.2 18.7 21.1 21.1 4.7 190.1 42.4 46.7 7.9 66.8 7.9 19.8 54.8 39.9 59.7 12.7 14.0 22.7 5.0 9.4 0.3 139.9 11.6 7.3 40.8 11.8 0.9 23.7 31.8 13.4 1.5 10.0 14.0 15.2 40.2 8.6 4.8 74.7 32.7 39.3 14.7 40.8 4.6 0.8 0.7 0.4 30.3 76.2 14.1 0.0 3.3 0.0 0.1 1.6 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.2 0.1 0.0 0.3 0.5 0.1 0.8 47.7 56.8 35.8 57.1 48.1 36.5 39.0 37.8 37.1 35.9 45.0 44.6 19.4 0.0 0.6 102.2 3.7 9.4 33.6 7.3 12.5 3.2 6.0 7.0 5.5 34.3 3.5 71.7 2.1 2.1 1.1 135.9 27.4 14.8 0.2 4.7 70.9 40.0 22.8 12.8 0.6 28.7 5.5 135.9 11.7 12.2 1.3 2.6 12.5 218.8 6.0 0.0 2.3 56.5 4.1 11.5 20.9 1.1 16.8 11.0 16.0 23.4 10.2 279.4 0.0 5.5 11.0 28.2 56.5 4.5 14.5 31.3 111.1 79.3 0.4 10.6 52.6 8.6 40.8 0.7 6.9 11.3 10.2 6.2 3.1 149.0 45.8 192.5 ODF3B FAP123 ENSG00000177989 "Outer dense fiber of sperm tails 3B" A8MYP8 22 50529710-50532580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 88.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 455.4;Late spermatids: 807.7;Respiratory ciliated cells: 417.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 92.0;intermediate monocyte: 75.6;myeloid DC: 55.5;neutrophil: 56.2;non-classical monocyte: 53.6" "Group enriched" "Detected in many" 16 "dendritic cells: 55.5;granulocytes: 56.2;monocytes: 92.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.5;Karpas-707: 40.8;U-266/70: 57.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA062837 Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 29: U-266 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA062837: AB_2684877" "unprognostic (4.30e-3)" "unprognostic (1.45e-2)" "unprognostic (5.98e-2)" "prognostic favorable (2.84e-4)" "unprognostic (2.60e-2)" "prognostic favorable (4.89e-4)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "unprognostic (5.24e-2)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (2.65e-5)" "unprognostic (2.72e-1)" "unprognostic (1.51e-2)" "unprognostic (6.10e-2)" "unprognostic (3.61e-2)" 21.9 6.0 6.3 26.8 4.0 13.3 24.3 6.6 4.4 13.8 22.3 8.4 6.9 6.1 0.9 14.4 88.8 9.8 18.6 8.4 11.8 16.4 32.4 36.4 14.0 32.7 35.3 2.1 9.0 3.9 7.9 6.8 16.0 19.9 1.6 0.0 46.5 5.5 5.4 13.5 12.3 2.1 17.0 24.1 12.2 16.3 11.9 5.9 21.9 1.7 4.2 6.8 11.3 6.4 2.9 1.8 0.3 0.7 0.0 3.6 1.7 0.1 0.6 0.1 1.8 3.2 13.5 1.0 3.4 0.1 0.5 8.1 0.0 0.0 0.0 1.4 0.9 0.6 2.5 2.4 10.0 0.0 6.5 2.1 1.7 0.0 0.0 1.0 0.2 1.0 0.8 40.8 0.0 0.0 0.0 1.5 0.2 0.8 1.9 1.5 0.2 7.2 0.0 0.0 0.2 11.6 1.3 1.6 0.2 0.2 1.2 2.0 1.0 0.3 1.1 0.8 0.2 57.9 5.9 0.9 1.3 0.2 1.0 10.1 92.0 11.3 0.6 75.6 0.9 4.2 1.6 1.1 55.5 2.2 1.0 0.6 56.2 0.1 53.6 5.3 2.3 28.6 6.3 4.0 6.6 4.4 8.4 11.8 32.7 35.3 16.0 17.0 11.9 6.4 73.3 19.2 52.9 0.0 32.3 24.1 21.9 70.0 61.5 0.2 63.8 61.8 5.3 24.3 66.5 3.7 0.0 3.4 8.9 8.6 0.0 76.7 144.5 455.4 8.9 33.0 20.4 0.4 0.0 74.8 39.6 29.1 27.5 22.0 6.3 0.0 21.0 30.2 36.2 0.0 0.1 23.6 46.8 66.0 33.2 807.7 5.3 82.5 17.8 1.0 113.8 0.0 7.2 0.0 0.0 35.0 29.4 3.4 73.3 30.4 53.0 16.9 417.1 0.1 0.0 36.0 27.6 10.0 3.7 46.4 36.1 5.5 11.4 0.0 9.2 33.7 OPLAH "5-Opase, OPLA" ENSG00000178814 "5-oxoprolinase, ATP-hydrolysing" O14841 8 144051266-144063965 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 66.5" "Group enriched" "Detected in many" 4 "Early spermatids: 115.7;Late spermatids: 231.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.1" "Group enriched" "Detected in many" 9 "granulocytes: 1.1;monocytes: 1.1" "Cell line enhanced" "Detected in many" "AN3-CA: 33.9;BEWO: 21.0;Hep G2: 18.8;PC-3: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026562, HPA028260, HPA052429" Uncertain Approved "Nucleoli fibrillar center" NA NA 34000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "HPA026562: AB_1854804, HPA028260: AB_10601383, HPA052429: AB_2681830" "unprognostic (7.89e-2)" "unprognostic (3.08e-2)" "unprognostic (1.69e-1)" "unprognostic (9.09e-2)" "unprognostic (2.21e-2)" "unprognostic (3.87e-3)" "unprognostic (2.04e-2)" "unprognostic (9.37e-2)" "unprognostic (2.90e-1)" "unprognostic (1.26e-1)" "unprognostic (6.82e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.53e-6)" "unprognostic (4.03e-3)" "unprognostic (4.33e-1)" "unprognostic (3.54e-2)" "unprognostic (8.24e-2)" 9.2 14.8 3.3 1.9 5.6 2.7 8.6 8.1 3.7 6.4 5.7 15.0 13.8 4.8 0.6 15.6 4.2 2.5 35.1 2.9 2.7 15.8 34.3 6.4 0.8 12.2 5.6 5.7 10.0 6.7 3.2 1.3 12.5 8.9 2.2 0.3 11.2 5.7 34.2 13.3 12.2 1.1 3.9 9.1 19.7 66.5 5.3 0.3 5.9 15.4 0.5 4.8 9.5 6.5 4.2 4.2 0.4 33.9 1.5 3.1 21.0 2.1 1.3 1.2 0.7 8.1 7.8 0.0 6.8 3.8 0.0 5.5 1.0 3.1 0.1 1.1 0.0 1.4 7.0 18.8 10.5 0.1 0.0 4.4 13.8 1.4 0.0 0.0 0.2 5.8 5.1 0.0 0.0 4.8 0.3 3.3 2.8 6.5 26.2 0.4 0.0 5.6 3.6 5.1 1.2 0.1 0.0 1.4 0.1 0.4 8.8 4.6 0.2 0.0 5.5 0.0 1.4 1.1 1.5 1.1 0.5 1.1 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.4 3.3 5.6 8.1 3.7 2.9 2.7 12.2 5.6 12.5 3.9 5.3 6.5 1.1 3.2 3.2 9.1 0.8 2.0 2.8 4.4 3.4 1.1 6.1 6.1 2.9 7.2 4.7 9.2 0.0 1.7 0.2 37.6 11.7 3.8 115.7 2.6 2.7 1.1 1.2 0.0 0.2 2.7 2.7 2.7 18.3 5.5 0.0 6.0 2.2 25.1 2.4 0.0 0.3 10.0 4.1 6.0 0.5 231.7 2.5 3.4 0.0 1.0 2.1 4.3 0.0 0.5 2.6 3.6 13.1 3.8 0.6 1.9 23.8 13.3 2.2 0.1 0.0 3.6 2.2 3.1 2.3 7.2 1.8 2.5 0.6 10.2 18.2 3.0 OSCAR ENSG00000170909 "Osteoclast associated Ig-like receptor" Q8IYS5 19 54094668-54102692 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 13.6;lung: 28.4;lymphoid tissue: 29.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 35.6;Kupffer cells: 27.8;Macrophages: 42.9;monocytes: 66.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 36 "classical monocyte: 43.0;eosinophil: 26.6;intermediate monocyte: 28.8;myeloid DC: 20.3;neutrophil: 40.0;non-classical monocyte: 27.0" "Group enriched" "Detected in many" 79 "dendritic cells: 20.3;granulocytes: 40.0;monocytes: 43.0" "Cell line enhanced" "Detected in some" "EFO-21: 13.9;HHSteC: 9.4;hTERT-HME1: 5.0;NB-4: 5.9;U-937: 17.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073996 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 84000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA073996: " "unprognostic (9.09e-2)" "unprognostic (6.79e-3)" "unprognostic (8.47e-3)" "unprognostic (2.14e-1)" "unprognostic (2.12e-2)" "unprognostic (9.04e-2)" "unprognostic (1.39e-1)" "unprognostic (3.86e-1)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.05e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.71e-5)" "unprognostic (1.84e-1)" "unprognostic (2.88e-2)" "unprognostic (9.69e-2)" "unprognostic (4.28e-2)" 3.7 1.8 0.9 2.3 0.7 13.6 1.8 0.1 1.6 2.2 0.0 1.5 0.0 1.3 0.0 1.5 3.2 1.3 1.9 0.1 0.7 1.5 2.4 28.4 0.3 1.3 0.7 1.1 1.3 0.1 1.0 0.6 0.9 1.7 0.3 0.0 2.2 0.3 0.5 2.1 1.6 1.7 0.7 29.8 1.2 0.9 0.8 0.2 1.1 0.6 0.6 2.2 2.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.3 0.0 13.9 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 9.4 0.6 0.0 0.0 0.2 0.6 5.0 0.8 0.0 0.0 0.0 0.4 0.1 0.1 0.0 5.9 0.3 0.1 1.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.8 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.6 0.5 17.9 0.0 0.0 43.0 26.6 0.3 28.8 0.1 0.0 0.2 0.4 20.3 0.0 0.1 0.0 40.0 0.0 27.0 0.8 0.2 16.8 0.9 0.7 0.1 1.6 0.1 0.7 1.3 0.7 0.9 0.7 0.8 1.7 0.2 3.2 5.9 0.3 0.3 0.8 0.6 0.7 0.6 0.0 0.7 0.4 0.3 1.5 2.1 0.0 0.0 0.3 0.6 0.1 0.0 0.3 0.0 0.1 0.3 0.9 0.0 1.7 1.9 0.0 0.4 0.6 0.0 0.1 1.3 0.3 0.0 0.0 35.6 0.0 1.0 0.3 0.0 27.8 11.6 0.2 0.0 42.9 0.0 1.0 66.4 0.0 1.0 0.0 0.3 0.4 0.0 0.0 0.4 0.3 0.1 0.2 3.7 0.4 0.0 0.2 0.1 0.6 0.5 0.4 0.1 0.3 0.7 0.4 0.1 0.3 OTULINL "FAM105A, FLJ11127, NET20" ENSG00000145569 "OTU deubiquitinase with linear linkage specificity like" Q9NUU6 5 14581792-14616180 "Enzymes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 29.5;dendritic cells: 36.7;Endometrial stromal cells: 16.6;Hofbauer cells: 100.7;Macrophages: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 17.7;HMC-1: 55.6;OE19: 16.1;THP-1: 16.9;U-937: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046638 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoli, Cytosol" "HPA046638: AB_2679731" "unprognostic (1.47e-1)" "unprognostic (6.64e-3)" "unprognostic (1.92e-2)" "unprognostic (1.15e-3)" "unprognostic (6.26e-2)" "unprognostic (1.13e-3)" "unprognostic (2.33e-2)" "unprognostic (2.27e-2)" "unprognostic (6.44e-2)" "unprognostic (2.42e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.13e-1)" "unprognostic (1.33e-2)" "unprognostic (2.38e-2)" "prognostic unfavorable (7.62e-4)" "unprognostic (3.14e-1)" "unprognostic (8.79e-3)" 3.1 2.7 1.2 6.8 1.1 30.3 4.1 1.3 1.6 3.8 4.8 12.3 6.6 1.5 1.4 1.7 1.4 2.7 0.9 1.1 1.8 3.6 1.4 13.1 5.4 2.3 1.5 2.0 7.6 1.2 2.5 4.2 2.1 8.3 13.3 0.5 1.4 10.0 0.4 1.7 9.4 2.5 2.4 7.9 3.3 2.5 1.9 3.4 2.8 0.8 3.6 5.2 3.1 3.6 0.0 0.8 1.6 0.0 0.3 0.0 6.9 2.0 1.8 0.5 1.0 2.8 1.7 0.1 1.1 0.9 2.8 0.1 3.7 1.6 0.7 1.1 4.9 4.6 17.7 0.4 1.7 0.1 55.6 0.1 0.3 0.2 0.0 0.0 0.1 2.9 0.0 7.1 0.2 1.4 0.0 1.7 2.5 16.1 11.9 0.5 0.7 2.0 0.0 13.9 6.0 7.0 0.9 0.6 0.0 1.7 0.6 16.9 0.0 0.9 4.4 0.4 1.6 0.0 0.0 0.1 1.0 27.2 0.4 0.2 33.4 0.3 5.5 16.2 7.3 0.1 6.7 7.2 33.8 0.1 9.0 9.1 8.6 19.2 12.7 25.0 12.8 24.6 1.2 1.1 1.3 1.6 1.1 1.8 2.3 1.5 2.1 2.4 1.9 3.6 10.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 7.4 7.9 0.0 0.0 0.0 29.5 0.0 0.9 36.7 0.0 1.9 0.4 0.0 0.9 16.6 1.1 0.0 0.0 0.0 6.2 2.2 1.4 0.0 1.2 0.0 0.5 0.0 0.0 100.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.3 0.0 0.0 12.9 0.0 0.0 0.0 0.0 1.2 0.0 0.0 4.4 0.0 0.0 3.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.4 8.8 0.2 0.0 0.0 PBLD "FLJ14767, MAWBP, MAWDBP" ENSG00000108187 "Phenazine biosynthesis like protein domain containing" P30039 10 68282660-68333049 "Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 171.5;kidney: 270.0;liver: 335.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 97.5;Distal tubular cells: 109.5;Hepatocytes: 216.9;Proximal enterocytes: 380.2;Proximal tubular cells: 426.5" "Cancer enhanced" "Detected in all" "liver cancer: 16.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA038035, HPA038036" Enhanced Approved Vesicles NA NA 1100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA038035: AB_10672470, HPA038036: AB_10675625" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (6.14e-2)" "unprognostic (8.83e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" "prognostic favorable (1.44e-4)" "unprognostic (8.25e-2)" "unprognostic (3.62e-2)" "unprognostic (3.36e-3)" "unprognostic (1.19e-1)" "unprognostic (6.26e-3)" "unprognostic (3.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.07e-2)" "unprognostic (8.28e-2)" "unprognostic (6.68e-2)" 8.9 11.2 2.9 8.4 5.5 9.3 4.5 5.3 5.3 3.9 4.2 33.2 171.5 5.9 3.8 3.4 7.2 9.4 6.2 3.0 4.6 270.0 335.2 3.9 5.5 4.9 4.1 3.6 63.0 5.6 2.3 4.2 4.2 5.6 27.6 8.7 4.5 5.1 5.6 5.6 146.4 5.0 3.0 4.6 54.8 3.8 4.4 2.1 5.5 3.1 2.2 5.4 2.1 8.9 3.8 7.5 7.1 4.9 6.4 3.6 3.3 15.1 9.5 5.6 5.8 6.9 9.5 4.2 5.6 10.6 2.3 5.8 3.3 3.9 4.8 2.0 5.4 3.3 9.3 6.4 3.0 5.0 3.3 6.4 4.0 3.4 4.2 10.1 3.5 4.0 3.1 9.2 8.9 5.9 4.7 8.7 2.1 3.0 3.2 8.0 9.4 7.1 11.3 5.4 4.1 5.5 10.1 5.8 7.0 2.0 20.0 5.9 10.9 5.5 3.9 2.7 2.5 5.5 4.3 6.3 6.6 2.7 1.4 2.6 2.8 1.5 0.4 1.4 0.8 0.8 0.6 0.4 2.8 0.6 1.1 0.7 3.3 1.8 0.9 1.2 1.1 1.2 2.9 5.5 5.3 5.3 3.0 4.6 4.9 4.1 4.2 3.0 4.4 8.9 1.6 3.2 4.2 3.6 4.5 1.9 1.7 2.2 1.2 5.0 6.2 2.8 3.5 24.3 4.3 55.2 10.4 3.9 3.7 97.5 109.5 8.8 1.2 17.9 5.7 3.4 7.2 6.6 1.8 31.8 2.0 3.2 33.1 6.5 1.3 8.2 6.4 216.9 3.1 10.1 2.8 42.6 2.0 10.4 4.4 0.4 4.1 5.5 1.8 3.7 5.0 5.5 3.1 3.0 7.5 12.5 46.4 3.0 1.5 2.0 380.2 426.5 12.9 17.2 0.0 2.0 6.6 1.6 1.4 1.8 0.6 3.1 2.8 9.6 57.3 3.0 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 201.9;Late spermatids: 53.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 60.9 23.7 35.7 2.9 35.5 3.5 28.4 36.6 35.8 3.7 17.5 4.7 6.5 3.8 1.8 9.3 3.2 2.8 4.3 32.4 41.0 23.3 148.0 2.6 1.3 43.4 40.1 5.1 4.9 18.2 8.6 4.4 37.6 7.2 2.8 2.4 35.3 9.3 12.1 4.7 7.7 1.4 37.8 1.5 9.1 10.7 49.0 2.0 4.6 6.6 2.0 2.9 4.4 37.0 6.1 19.3 6.5 17.2 25.4 8.9 6.6 3.4 15.5 6.9 7.5 8.8 6.0 0.0 7.4 6.0 9.6 6.8 7.7 39.5 1.5 2.8 11.0 10.3 57.4 41.2 21.0 0.1 10.8 40.2 10.1 5.8 12.4 4.4 5.7 14.3 17.4 0.0 2.1 44.6 9.2 4.6 12.0 15.1 16.2 8.3 13.0 3.2 5.7 1.9 15.2 21.0 33.6 18.0 15.5 4.8 14.6 2.7 6.3 7.8 6.6 8.8 4.7 3.5 4.8 0.1 7.7 5.7 6.7 0.0 1.3 0.0 0.5 0.3 0.5 0.0 0.1 0.5 0.9 0.2 0.9 0.5 0.1 0.1 0.1 0.3 0.5 0.7 35.7 35.5 36.6 35.8 32.4 41.0 43.4 40.1 37.6 37.8 49.0 37.0 0.9 0.0 3.0 26.4 1.4 1.3 1.6 9.1 2.8 5.6 4.8 5.8 4.4 11.5 3.0 3.7 2.1 17.4 0.6 27.6 1.9 3.1 18.4 2.3 7.1 1.5 9.0 28.0 18.5 1.8 4.2 3.2 5.6 3.0 8.9 16.0 4.6 201.9 12.3 0.0 18.6 5.0 0.0 7.0 1.8 53.2 0.6 1.8 5.4 7.5 18.9 9.4 2.1 10.1 16.7 2.3 8.5 4.1 0.1 3.1 23.6 39.0 1.5 4.8 0.0 2.2 2.2 11.2 4.7 4.1 0.6 25.4 1.2 6.0 6.4 1.3 PDGFRL PRLTS ENSG00000104213 "Platelet derived growth factor receptor like" Q15198 8 17576433-17644071 "Disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Fibroblasts: 186.2;Leydig cells: 74.6;Peritubular cells: 70.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 189.4;BJ hTERT+: 159.1;HSkMC: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052801 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA052801: AB_2681956" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (5.10e-2)" "unprognostic (1.59e-2)" "unprognostic (7.39e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "unprognostic (3.86e-1)" "unprognostic (7.46e-2)" "unprognostic (1.63e-1)" "unprognostic (6.72e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (4.47e-3)" "unprognostic (6.00e-3)" 34.1 4.2 2.5 3.9 3.5 0.2 51.9 2.8 3.0 27.8 1.9 9.0 0.9 15.8 10.3 3.0 23.3 13.4 11.1 2.3 2.3 1.3 0.7 4.7 1.2 2.7 2.6 42.9 6.9 9.0 7.4 9.0 2.5 5.4 3.1 0.6 13.1 6.7 18.4 11.0 2.6 26.0 2.4 0.8 6.2 6.5 2.9 3.8 33.0 38.0 2.0 6.5 12.0 3.3 0.0 17.7 1.0 189.4 5.6 2.5 13.8 4.6 159.1 7.5 31.3 1.0 0.2 0.0 0.9 2.5 24.7 0.0 11.6 0.9 3.7 0.2 14.5 0.0 5.3 4.1 14.6 0.0 0.0 86.9 0.1 9.2 0.1 0.0 13.0 1.6 0.0 2.4 1.1 12.5 0.2 0.4 9.9 0.7 3.6 0.0 0.2 0.4 1.0 11.4 0.6 1.2 1.4 1.7 3.3 11.4 0.6 0.0 2.6 0.2 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.5 2.8 3.0 2.3 2.3 2.7 2.6 2.5 2.4 2.9 3.3 15.5 0.0 3.6 2.3 0.3 13.3 0.5 4.3 0.6 0.6 2.9 3.3 4.5 1.5 2.8 0.0 0.0 14.9 0.7 0.4 0.0 4.1 36.0 2.4 5.4 4.1 1.2 0.0 1.1 7.1 19.9 186.2 0.5 4.7 0.0 0.3 1.4 0.2 3.5 0.0 3.5 1.3 2.0 0.0 14.6 6.7 74.6 1.6 10.6 1.9 1.6 1.4 0.0 3.0 1.3 3.1 0.1 70.7 0.2 1.9 0.4 0.1 0.2 0.4 0.0 8.0 10.7 0.8 1.9 0.6 9.9 9.7 1.7 1.5 0.4 0.5 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 4700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 17.9 23.6 0.3 15.2 0.3 17.9 13.8 0.2 1.4 14.5 2.7 20.1 13.9 12.4 30.2 6.1 14.0 19.6 9.9 0.6 0.8 14.5 80.2 17.7 11.1 0.5 0.6 11.5 26.6 10.7 12.7 47.4 0.4 32.3 25.0 4.2 13.7 7.9 4.2 8.8 12.8 17.0 0.3 10.1 33.4 15.3 0.9 4.5 30.8 4.3 12.0 17.9 9.5 0.7 24.0 14.6 17.7 21.5 80.3 71.9 95.0 44.9 74.5 24.5 66.9 47.8 21.6 0.0 57.6 69.9 15.7 12.5 7.8 27.4 25.7 1.1 8.8 10.4 3.9 56.7 33.2 26.5 1.4 62.3 40.2 16.6 34.5 26.1 84.0 10.1 13.6 60.4 16.9 29.6 7.2 31.3 13.1 54.5 15.6 6.7 13.0 67.5 20.7 13.9 19.3 11.4 22.0 24.0 40.4 28.7 21.4 32.3 47.2 6.2 19.5 29.4 12.3 18.1 5.0 10.8 20.2 21.0 21.5 0.0 9.3 0.3 1.4 2.4 2.3 3.5 1.0 0.8 5.5 1.1 0.6 0.6 0.2 0.5 0.5 12.8 0.0 2.3 0.3 0.3 0.2 1.4 0.6 0.8 0.5 0.6 0.4 0.3 0.9 0.7 17.2 19.2 30.7 2.6 5.6 5.0 6.0 6.4 3.4 13.1 6.9 4.7 2.7 35.8 11.3 5.5 39.6 41.8 3.1 5.4 0.0 32.2 1.6 5.4 13.1 24.3 8.4 5.5 9.6 28.6 133.6 20.7 30.5 21.1 3.8 7.3 37.5 50.1 12.1 0.0 7.1 36.9 0.0 7.8 5.5 2.0 24.2 4.4 8.8 5.6 5.0 2.3 0.0 1.0 2.5 11.9 7.6 22.2 40.1 18.1 3.5 5.3 6.4 28.4 13.1 3.6 17.6 1.3 1.5 3.4 4.1 50.2 3.1 23.3 15.1 4.5 PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.0;Inhibitory neurons: 142.2;Langerhans cells: 210.4;Microglial cells: 179.9;Oligodendrocyte precursor cells: 543.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Cell line enhanced" "Detected in many" "ASC diff: 54.5;hTEC/SVTERT24-B: 86.1;LHCN-M2: 57.3;REH: 62.3;RH-30: 90.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" 31.2 29.5 18.8 13.9 20.8 2.9 25.8 9.0 21.2 30.2 9.0 37.6 5.5 22.9 8.9 12.0 33.9 12.7 17.0 20.6 15.5 5.6 62.2 24.4 4.4 14.8 30.5 31.0 13.8 1.5 8.8 26.1 13.6 19.2 21.5 3.8 10.2 14.8 13.1 20.0 25.1 16.7 11.8 20.3 25.5 5.5 21.4 3.4 16.6 20.8 3.6 30.9 27.0 13.8 0.0 1.9 0.0 0.0 54.5 10.5 0.1 9.2 34.7 5.8 7.1 0.7 0.0 0.0 0.2 13.0 18.0 1.7 0.0 1.7 7.8 0.0 0.0 0.0 4.0 0.1 22.3 0.0 0.1 19.8 15.5 86.1 14.0 16.1 0.0 0.0 0.0 0.1 57.3 0.1 0.1 0.0 0.9 7.6 5.2 62.3 90.7 0.1 1.1 0.0 1.8 2.3 19.4 1.8 0.1 0.7 0.2 0.0 0.0 22.3 8.3 21.1 8.8 0.1 0.0 0.0 29.3 0.1 3.7 0.0 71.1 0.0 0.0 79.4 0.4 0.2 0.0 0.2 83.6 0.0 0.0 0.0 1.5 0.0 16.7 0.4 0.3 28.4 18.8 20.8 9.0 21.2 20.6 15.5 14.8 30.5 13.6 11.8 21.4 13.8 4.0 6.4 70.9 53.8 1.6 15.6 6.1 13.5 6.8 5.7 0.9 1.7 2.6 8.6 11.1 0.0 0.0 1.9 0.2 75.7 0.0 2.5 0.1 1.4 37.8 4.1 4.9 0.4 121.0 4.0 31.5 107.3 1.1 4.4 6.3 7.8 4.2 135.0 3.3 0.0 142.2 11.9 4.1 42.5 210.4 1.9 88.0 50.1 21.4 179.9 35.2 14.0 1.0 543.4 3.5 1.6 24.2 75.2 0.5 21.9 39.5 0.3 2.5 1.3 0.0 4.8 8.7 0.4 2.1 1.4 14.5 4.8 2.4 41.0 36.0 1.4 PKM "OIP3, PK3, PKM2, THBP1" ENSG00000067225 "Pyruvate kinase M1/2" P14618 15 72199029-72231822 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Translation regulation" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 4207.6;tongue: 2900.8" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 2065.2;Late spermatids: 1763.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019421, HPA029501" Uncertain Enhanced Cytosol No No 310000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "CAB019421: AB_2252325, HPA029501: AB_10602118" "unprognostic (8.73e-3)" "unprognostic (4.63e-3)" "unprognostic (1.68e-2)" "unprognostic (3.09e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (1.30e-4)" "prognostic unfavorable (2.74e-6)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.51e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (5.17e-5)" "unprognostic (3.16e-1)" "unprognostic (3.22e-1)" "unprognostic (7.85e-2)" "unprognostic (3.17e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-2)" 190.5 600.9 539.0 341.4 552.3 439.0 190.5 586.8 629.9 406.8 755.0 225.0 170.8 202.8 205.7 658.3 240.0 212.0 779.6 549.1 561.6 549.5 32.2 236.9 284.1 640.0 559.1 169.4 112.6 269.6 224.1 168.6 636.2 252.6 206.2 1266.7 389.8 291.6 4207.6 350.5 218.0 298.9 522.3 239.2 228.6 235.1 677.1 203.5 174.6 2900.8 429.2 578.5 374.9 530.6 1584.6 3937.1 788.9 938.8 914.3 1009.4 638.7 1684.6 3878.2 2619.1 2623.6 1094.4 1931.2 1184.5 1627.3 3157.6 1937.8 2253.9 2480.9 3383.2 2051.7 2134.0 1126.5 727.7 1809.1 929.7 637.1 955.2 1525.1 926.4 1559.2 2025.1 810.9 3403.0 1558.6 587.3 182.8 933.3 4267.0 965.1 359.4 419.6 966.2 2438.6 1433.3 1046.5 2560.0 2301.7 3557.2 1973.8 804.4 871.5 2226.3 1344.7 1755.4 1291.4 932.0 675.7 1247.3 3003.7 1622.0 2928.7 3110.3 1170.0 1762.1 1037.2 3720.5 1534.4 3002.3 131.9 836.3 138.6 192.6 466.7 187.9 205.2 254.1 190.4 685.6 142.9 215.8 162.5 100.7 108.4 380.1 140.5 334.0 1261.7 539.0 552.3 586.8 629.9 549.1 561.6 640.0 559.1 636.2 522.3 677.1 530.6 95.9 118.6 88.1 107.7 169.6 565.5 708.9 2065.2 307.9 480.7 157.8 174.7 313.2 87.2 759.4 829.4 369.1 566.1 100.2 358.9 802.2 1395.6 315.0 169.2 77.3 207.7 282.2 44.8 90.2 597.0 1416.7 220.1 138.1 188.0 206.7 144.0 73.2 4.3 750.0 1065.0 97.6 166.8 925.7 297.7 532.9 1763.1 157.2 558.8 355.8 38.4 1255.0 784.1 78.2 53.3 33.4 1213.2 264.5 268.1 209.9 431.4 389.1 208.7 396.9 708.6 124.9 160.9 398.2 43.4 98.6 341.6 389.0 575.7 192.7 157.4 380.7 860.7 PLA2G7 "LDL-PLA2, PAFAH" ENSG00000146070 "Phospholipase A2 group VII" Q13093 6 46704201-46735693 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Asthma, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.2;placenta: 23.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 372.2;Macrophages: 140.9" "Cancer enhanced" "Detected in all" "prostate cancer: 37.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 43.4" "Group enriched" "Detected in many" 49 "dendritic cells: 14.1;monocytes: 43.4" "Cell line enhanced" "Detected in some" "NTERA-2: 1.7;PC-3: 3.4;RT4: 1.6;U-2 OS: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 7380000 290000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.63e-3)" "unprognostic (2.82e-3)" "unprognostic (8.69e-2)" "unprognostic (3.00e-1)" "unprognostic (1.47e-1)" "unprognostic (6.26e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-2)" "unprognostic (5.33e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "unprognostic (9.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" 4.5 3.1 1.6 22.9 3.6 2.8 2.6 2.7 4.5 2.5 0.4 7.5 4.1 4.8 1.1 0.6 1.9 6.0 0.6 2.6 1.4 0.3 6.9 7.2 26.8 3.9 2.6 1.1 0.8 21.0 2.1 23.3 4.2 13.1 10.3 0.6 1.4 2.6 0.4 3.6 3.3 2.8 2.6 27.2 2.9 0.9 8.9 4.9 20.2 0.0 10.0 11.1 0.3 7.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.9 0.7 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 3.4 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.4 0.4 0.4 0.0 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.3 43.4 0.3 0.1 9.2 0.3 0.3 0.0 0.0 14.1 0.0 0.0 0.1 0.5 0.0 0.5 0.3 0.0 11.9 1.6 3.6 2.7 4.5 2.6 1.4 3.9 2.6 4.2 2.6 8.9 7.4 0.5 0.0 1.3 0.3 3.6 0.8 4.4 0.0 0.0 0.2 0.3 4.3 0.3 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.6 0.1 1.6 50.3 0.6 3.5 0.0 7.1 0.0 5.1 1.8 0.0 1.5 0.0 0.0 0.0 0.0 372.2 1.7 4.8 0.3 0.0 24.6 4.9 0.1 0.0 140.9 10.6 11.2 29.3 0.3 0.0 6.0 0.3 0.3 0.0 0.0 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.9 0.6 0.1 0.0 0.1 0.1 3.1 0.8 8.9 0.2 3.8 PLBD1 FLJ22662 ENSG00000121316 "Phospholipase B domain containing 1" Q6P4A8 12 14503661-14567883 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 187.7;Hofbauer cells: 105.6;Kupffer cells: 109.4;Macrophages: 116.3;monocytes: 192.8;Paneth cells: 105.9" "Cancer enhanced" "Detected in all" "testis cancer: 113.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 662.9;intermediate monocyte: 204.4;myeloid DC: 357.3;neutrophil: 443.8" "Group enriched" "Detected in all" 135 "dendritic cells: 357.3;granulocytes: 443.8;monocytes: 662.9" "Cell line enhanced" "Detected in many" "AN3-CA: 48.6;BEWO: 98.4;CAPAN-2: 245.6;MCF7: 46.3" "Not detected" "Not detected" HPA040303 Enhanced "Intracellular and membrane" NA NA 3400000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA040303: AB_2676922" "unprognostic (9.13e-3)" "unprognostic (5.77e-2)" "unprognostic (2.29e-1)" "unprognostic (7.87e-2)" "unprognostic (1.71e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (4.80e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.12e-1)" "unprognostic (3.03e-3)" "unprognostic (3.47e-1)" "unprognostic (1.97e-1)" "unprognostic (4.99e-2)" "unprognostic (5.44e-2)" 29.4 5.6 2.1 33.7 2.5 285.9 27.8 2.4 3.7 22.4 25.9 58.8 28.2 13.5 10.6 56.3 16.6 33.1 32.6 2.1 2.4 26.3 10.6 64.0 9.2 3.5 3.2 4.4 30.0 3.2 3.4 35.9 3.2 10.2 79.2 0.8 11.9 15.3 9.9 24.8 42.6 28.1 3.1 25.2 36.6 10.0 2.8 7.8 6.1 17.2 32.7 58.5 29.6 4.8 7.1 5.0 0.5 48.6 0.3 0.0 98.4 0.2 0.0 3.0 2.4 14.1 245.6 0.0 1.4 1.0 0.4 9.4 0.0 0.0 0.5 0.0 0.1 0.0 6.4 0.0 3.8 0.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 21.2 0.0 1.1 46.3 0.1 0.2 16.5 0.7 0.3 0.1 0.1 0.5 0.7 28.9 0.0 0.4 30.2 14.8 1.9 26.5 9.0 9.6 0.0 0.5 0.4 0.0 0.6 8.7 23.7 0.2 0.0 0.1 0.4 0.4 662.9 5.8 1.0 204.4 0.6 3.6 0.5 0.4 357.3 0.8 0.7 0.7 443.8 1.7 73.5 4.1 0.9 423.2 2.1 2.5 2.4 3.7 2.1 2.4 3.5 3.2 3.2 3.1 2.8 4.8 15.5 9.6 8.6 0.3 2.9 6.8 8.8 4.9 6.8 0.0 11.9 6.6 16.5 30.0 20.4 33.1 0.0 94.5 1.5 67.8 11.7 13.1 51.8 2.5 9.1 7.2 9.1 1.7 1.6 46.5 187.7 59.6 13.3 0.9 5.1 5.9 4.6 2.9 105.6 0.0 0.9 31.3 6.1 109.4 68.6 5.8 26.1 116.3 5.4 7.5 192.8 1.6 1.0 1.5 0.2 28.6 105.9 27.8 3.6 3.8 52.8 15.7 19.0 0.2 0.0 12.0 10.4 17.4 12.0 17.8 19.9 70.3 1.6 6.1 75.2 30.1 PLP2 "A4, A4-LSB, MGC126187" ENSG00000102007 "Proteolipid protein 2" Q04941 X 49171898-49175235 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 496.5;Exocrine glandular cells: 496.6;Pancreatic endocrine cells: 550.1;Suprabasal keratinocytes: 504.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042415 Approved NA NA 250000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA042415: AB_10796907" "unprognostic (1.40e-1)" "unprognostic (6.67e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (3.32e-5)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (1.04e-3)" "unprognostic (4.14e-2)" "unprognostic (2.58e-2)" "unprognostic (9.99e-2)" "unprognostic (1.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.55e-10)" "unprognostic (1.66e-1)" "unprognostic (1.25e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 105.1 195.8 17.3 87.6 17.6 358.6 99.8 19.8 21.3 173.6 27.0 164.1 71.0 162.0 42.7 381.7 124.4 53.2 121.0 17.3 24.4 61.3 36.6 118.6 59.9 22.7 21.9 110.3 250.8 37.5 97.4 60.8 20.4 97.8 130.5 6.2 119.3 104.7 99.0 390.6 96.2 156.6 20.2 79.1 114.6 23.3 21.7 77.9 46.8 53.3 148.0 182.8 264.3 19.7 539.1 312.8 0.4 1.0 131.6 388.9 1.6 278.2 223.5 339.9 255.4 115.2 248.4 193.5 68.1 209.2 340.7 444.1 260.5 517.4 214.5 490.2 104.2 71.4 421.1 3.1 210.0 136.0 304.2 174.7 505.6 443.5 516.5 317.6 260.9 63.0 55.1 239.6 249.2 346.0 14.9 346.2 3.3 263.6 456.2 48.9 300.1 563.8 464.6 355.1 69.4 120.6 394.4 155.6 244.4 2.6 340.6 77.0 293.7 194.4 185.4 344.6 472.4 102.2 100.6 50.9 461.3 359.7 464.4 486.8 287.7 148.7 59.9 99.8 100.7 226.4 214.3 112.8 298.5 144.8 107.8 93.4 320.0 70.5 63.7 694.2 265.8 235.8 17.3 17.6 19.8 21.3 17.3 24.4 22.7 21.9 20.4 20.2 21.7 19.7 49.3 73.7 38.2 1.0 160.8 439.7 306.0 496.5 167.9 0.4 67.8 115.4 33.3 57.2 101.9 80.9 0.0 2.7 232.0 134.6 21.5 379.6 16.4 71.8 27.8 63.7 111.7 43.1 0.6 496.6 27.2 110.4 71.9 51.1 88.7 15.4 55.3 12.8 157.5 0.0 0.7 254.9 138.4 130.3 210.5 20.3 169.9 133.3 224.1 4.7 146.4 18.9 35.0 0.0 0.6 550.1 200.3 60.9 148.5 219.5 141.8 9.4 92.9 1.1 124.9 76.1 128.7 4.2 1.4 401.0 504.9 6.4 162.7 29.6 285.2 334.1 PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 319.8;BJ hTERT+ SV40 Large T+ RasG12V: 418.6;HHSteC: 292.9;SK-MEL-30: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB070421: AB_11153452, HPA068923: AB_2686059" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (5.34e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (3.35e-1)" "unprognostic (5.22e-2)" "unprognostic (7.73e-3)" "unprognostic (9.19e-3)" "unprognostic (6.93e-3)" "unprognostic (3.07e-3)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.26e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" 60.6 23.0 11.4 86.7 12.5 64.4 45.9 12.7 17.6 25.9 11.9 65.0 39.8 28.2 31.0 47.9 40.0 66.1 24.3 12.1 13.5 71.9 49.2 49.3 40.6 17.4 14.2 34.9 38.3 16.8 15.4 56.3 15.3 23.7 59.5 9.8 49.1 49.6 10.8 13.6 45.4 41.9 16.2 64.5 44.0 17.1 14.7 30.0 27.8 17.6 39.4 68.1 29.5 14.0 106.2 41.5 26.4 12.1 40.9 65.0 40.5 32.6 88.4 319.8 418.6 34.0 88.1 8.4 75.6 20.6 245.9 86.2 21.2 32.7 56.6 32.9 21.6 66.1 12.5 25.2 292.9 40.3 35.4 106.3 53.3 36.6 182.3 52.6 49.4 19.1 44.7 104.0 66.9 41.0 30.6 16.1 25.8 71.6 37.6 27.4 28.1 2.9 95.9 29.6 16.3 0.0 42.6 20.9 569.9 35.8 20.7 46.8 30.6 26.9 22.7 59.1 55.8 79.2 15.6 0.4 27.0 29.0 23.3 41.1 157.6 44.3 20.8 159.6 30.0 25.2 13.5 18.5 105.8 19.7 9.3 13.9 100.0 57.8 94.8 28.5 8.3 79.3 11.4 12.5 12.7 17.6 12.1 13.5 17.4 14.2 15.3 16.2 14.7 14.0 191.4 35.3 43.0 12.7 28.2 37.0 106.5 92.1 26.2 0.7 36.0 22.6 7.3 124.4 110.4 95.6 0.0 53.7 25.4 134.2 74.3 291.6 2.0 56.1 24.5 135.2 33.1 18.3 7.1 217.4 114.1 74.8 47.9 58.2 28.4 60.5 100.6 29.7 139.9 0.0 9.0 71.5 79.3 86.2 162.9 6.8 114.9 185.5 48.0 35.6 72.3 64.3 32.0 7.1 0.3 157.6 110.3 45.9 18.2 79.6 40.7 75.0 133.5 1.6 39.5 63.4 59.2 1.5 2.4 21.8 28.6 44.5 25.9 42.6 69.4 211.9 PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Microglial cells: 1508.4;Oligodendrocytes: 470.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.5;intermediate monocyte: 33.4;myeloid DC: 36.0;neutrophil: 81.6;non-classical monocyte: 37.3" "Group enriched" "Detected in many" 13 "dendritic cells: 36.0;granulocytes: 81.6;monocytes: 57.5" "Cell line enhanced" "Detected in some" "HHSteC: 19.4;U-2197: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 720000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies" "HPA017268: AB_10965928, HPA070793: AB_2686313" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (3.05e-1)" "unprognostic (3.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-2)" "unprognostic (1.57e-1)" "unprognostic (5.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (5.44e-2)" "unprognostic (3.91e-3)" "unprognostic (8.71e-2)" "unprognostic (3.35e-1)" "unprognostic (2.66e-2)" 12.4 9.4 13.3 7.3 14.1 5.2 11.5 9.6 13.3 12.7 16.8 5.3 4.2 10.7 3.5 7.5 10.1 17.4 10.2 11.3 25.6 10.7 3.1 17.1 2.4 18.0 17.3 9.4 3.6 16.2 3.3 4.7 19.2 7.6 4.6 18.2 6.2 7.7 5.0 15.5 7.1 16.2 16.2 9.4 3.8 5.9 22.3 2.5 6.8 10.0 2.8 8.5 8.9 29.1 0.0 0.0 5.8 0.0 0.0 0.0 6.7 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 7.7 2.2 1.8 0.0 0.0 0.7 2.8 8.6 0.4 19.4 0.0 0.0 7.7 0.6 0.0 2.3 8.9 0.0 0.0 0.1 1.7 0.9 1.1 0.6 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.4 0.2 2.4 0.4 0.0 1.8 0.8 0.9 0.0 7.6 3.9 45.9 0.0 0.1 0.0 0.0 3.5 0.1 0.0 10.7 57.5 11.8 1.3 33.4 2.7 0.0 0.0 0.3 36.0 0.0 0.0 0.0 81.6 4.4 37.3 1.6 0.0 17.7 13.3 14.1 9.6 13.3 11.3 25.6 18.0 17.3 19.2 16.2 22.3 29.1 101.4 16.0 8.9 131.9 2.6 36.8 23.8 12.3 41.5 44.2 14.4 45.3 10.9 15.7 10.9 5.5 8.4 0.9 2.9 7.1 0.0 6.9 2.9 16.5 7.6 45.3 3.0 10.5 190.9 0.0 8.1 97.2 1.1 19.4 31.6 80.9 82.1 4.2 94.3 1.7 59.9 27.3 8.2 91.3 46.3 2.1 19.3 147.7 7.2 1508.4 94.5 25.5 5.2 158.3 470.2 1.0 16.6 57.2 3.8 5.5 16.0 22.2 3.0 73.6 19.7 110.1 12.7 1.6 1.2 35.5 38.1 1.2 4.2 71.4 8.8 11.7 PLXND1 KIAA0620 ENSG00000004399 "Plexin D1" Q9Y4D7 3 129555214-129606676 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 107.3;Endothelial cells: 102.1;Hepatic stellate cells: 132.1;Hofbauer cells: 81.5;Kupffer cells: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 10.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 392.3;HSkMC: 286.1;HUVEC TERT2: 346.1;TIME: 414.4" "Group enriched" "Detected in all" 4 "amygdala: 36.6;basal ganglia: 33.1;cerebral cortex: 27.4;hippocampal formation: 26.3" "Low region specificity" "Detected in all" CAB020819 Approved NA NA 120000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB020819: " "unprognostic (8.97e-3)" "unprognostic (1.95e-1)" "unprognostic (6.30e-2)" "unprognostic (8.35e-2)" "unprognostic (1.28e-2)" "unprognostic (3.00e-3)" "unprognostic (6.35e-2)" "unprognostic (4.51e-2)" "unprognostic (3.69e-1)" "unprognostic (3.02e-3)" "unprognostic (3.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (5.93e-7)" "unprognostic (1.30e-1)" "unprognostic (3.21e-2)" "unprognostic (3.17e-2)" "unprognostic (1.00e-2)" 72.6 22.1 32.0 37.4 38.1 26.5 47.4 36.2 35.6 58.4 26.1 19.5 6.0 33.5 17.6 21.5 35.0 39.4 39.8 29.3 34.2 24.7 18.3 67.5 34.7 48.7 43.5 16.3 13.9 18.0 11.1 112.4 43.8 19.0 16.9 3.5 13.3 27.0 12.9 19.5 20.9 52.6 38.8 33.6 15.8 10.8 49.0 62.7 29.5 39.8 23.2 37.1 26.8 43.2 10.0 57.7 47.4 16.3 392.3 167.9 98.4 42.8 123.1 25.5 29.5 13.4 8.1 2.1 179.9 152.9 13.2 0.6 25.9 0.6 7.5 1.9 3.2 40.7 30.2 61.4 44.8 13.5 11.0 286.1 1.7 26.4 2.8 36.6 346.1 2.1 14.5 1.5 34.8 31.0 2.4 44.2 11.8 2.4 8.0 47.4 32.0 51.8 10.2 2.3 27.6 1.1 11.0 3.5 15.9 107.6 15.5 59.7 414.4 21.5 28.5 0.6 32.4 1.9 2.2 19.9 7.5 29.2 19.0 0.0 10.7 0.0 1.7 5.1 6.8 0.0 1.2 1.4 2.9 0.0 0.0 0.1 0.2 3.1 5.2 3.6 0.0 1.7 32.0 38.1 36.2 35.6 29.3 34.2 48.7 43.5 43.8 38.8 49.0 43.2 107.3 3.2 27.2 12.4 3.6 8.0 0.4 2.1 0.6 0.1 7.6 3.4 10.6 5.7 3.1 0.0 0.0 7.1 16.9 0.2 0.0 1.4 1.4 3.7 52.5 102.1 13.1 12.6 10.4 3.5 16.4 19.5 5.6 6.2 22.2 1.3 132.1 7.7 81.5 0.0 0.6 3.2 6.1 75.6 31.8 1.8 38.8 41.7 8.8 27.2 29.4 6.5 10.3 0.5 27.7 2.7 0.1 13.9 12.9 0.5 0.0 0.3 1.2 0.3 32.9 14.4 37.1 0.6 4.0 1.5 4.4 5.3 14.4 49.5 0.5 0.6 POTEF "A26C1B, POTE2alpha, POTEACTIN" ENSG00000196604 "POTE ankyrin domain family member F" A5A3E0 2 130073535-130129222 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 1.6;testis: 1.7" "Cell type enhanced" "Detected in some" "Melanocytes: 1.8;NK-cells: 1.0;Smooth muscle cells: 1.3;Spermatocytes: 2.2;Spermatogonia: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.7;BEWO: 2.0;CACO-2: 2.3;MCF7: 1.8;U-2 OS: 5.6;U-266/70: 2.7" "HPA041264, HPA041271, HPA043260" Uncertain NA NA 1900000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA041264: AB_2677383, HPA041271: AB_2677386, HPA043260: AB_2678396" "unprognostic (1.36e-1)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (2.98e-1)" "unprognostic (1.01e-1)" "unprognostic (1.18e-2)" "unprognostic (8.13e-3)" "unprognostic (1.44e-2)" "unprognostic (2.90e-2)" "unprognostic (1.16e-1)" "unprognostic (3.38e-1)" "unprognostic (2.23e-1)" "unprognostic (3.50e-1)" "unprognostic (1.02e-1)" "unprognostic (4.48e-1)" "unprognostic (1.05e-2)" "unprognostic (9.35e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 2.7 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.8 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.1 2.7 0.8 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 1.6 0.1 0.2 0.0 0.0 0.2 1.6 0.9 0.5 0.5 1.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.3 2.2 1.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40072710-40097260 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 251.9;Kupffer cells: 315.8;Langerhans cells: 328.8;Macrophages: 271.3;monocytes: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 1254.3;eosinophil: 624.2;intermediate monocyte: 1006.3;myeloid DC: 1091.1;neutrophil: 683.9;non-classical monocyte: 815.7" "Group enriched" "Detected in all" 4 "dendritic cells: 1091.1;granulocytes: 683.9;monocytes: 1254.3" "Cell line enhanced" "Detected in all" "SK-BR-3: 1082.7;THP-1: 1449.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 240000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" 69.8 59.4 92.9 92.7 95.6 117.5 95.7 100.4 135.9 70.1 106.1 50.5 32.1 72.7 60.1 45.1 55.4 57.1 45.3 93.6 101.2 75.8 54.1 128.5 93.9 97.0 96.7 68.6 42.6 79.2 39.0 74.8 99.6 73.4 58.8 89.4 56.8 63.2 21.3 40.3 39.2 95.3 101.6 177.0 45.1 37.6 99.1 78.0 60.0 37.1 75.1 79.1 34.7 113.5 115.6 62.5 93.7 81.0 106.5 92.1 209.8 68.4 127.9 153.0 183.3 350.1 270.5 140.1 118.1 65.2 112.2 209.5 154.9 112.7 163.6 186.4 151.4 100.3 127.2 155.5 137.5 233.7 158.9 103.1 107.5 108.7 126.4 79.7 190.9 108.8 167.7 247.0 80.6 168.1 109.8 88.3 258.3 163.9 93.8 116.0 263.7 226.1 89.2 152.0 114.1 96.9 247.9 1082.7 298.6 111.7 199.3 1449.6 85.2 100.7 147.1 70.7 174.9 161.2 383.8 133.9 109.4 408.7 155.5 85.7 1254.3 624.2 122.2 1006.3 137.9 118.8 171.5 131.3 1091.1 118.6 227.0 168.3 683.9 100.3 815.7 101.8 204.1 1586.9 92.9 95.6 100.4 135.9 93.6 101.2 97.0 96.7 99.6 101.6 99.1 113.5 45.2 28.9 47.7 19.9 33.3 39.6 77.1 30.8 34.7 46.6 55.3 37.5 15.7 41.5 40.0 38.6 16.7 51.7 28.9 4.7 5.9 59.0 64.8 13.8 46.4 49.6 19.9 40.1 28.4 42.1 66.5 56.6 14.8 18.2 84.9 34.6 47.5 9.3 251.9 25.2 39.2 8.1 20.3 315.8 328.8 87.6 31.4 271.3 67.6 31.9 227.2 120.3 28.8 27.6 22.7 22.2 6.0 39.5 34.2 42.4 3.2 18.5 32.3 37.0 19.7 30.5 49.3 17.5 33.0 19.1 27.3 41.2 43.5 39.4 11.4 35.6 PRDX3 "AOP-1, AOP1, MER5, SP-22" ENSG00000165672 "Peroxiredoxin 3" P30048 10 119167720-119178812 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1060.4;Proximal tubular cells: 937.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008656, HPA041488, CAB079909" Enhanced Supported Mitochondria NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB008656: AB_1620979, CAB079909: AB_2809998, HPA041488: AB_2677508" "unprognostic (8.29e-2)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (1.72e-3)" "unprognostic (4.62e-3)" "unprognostic (2.40e-1)" "unprognostic (2.06e-1)" "unprognostic (3.65e-2)" "unprognostic (1.29e-2)" "unprognostic (9.48e-2)" "unprognostic (6.03e-3)" "unprognostic (2.77e-1)" "unprognostic (2.77e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" 165.7 335.3 92.4 96.0 92.6 82.3 138.3 101.3 116.0 103.4 139.2 133.3 137.8 87.0 120.8 83.3 116.7 88.0 278.2 95.2 104.5 385.7 571.2 74.9 108.4 97.2 97.1 74.9 96.2 223.8 60.0 126.3 99.0 126.7 139.8 52.5 132.1 131.7 376.0 38.0 132.1 130.0 100.4 76.3 97.5 48.3 98.6 98.3 176.7 402.7 104.0 112.8 65.1 102.7 350.6 392.2 234.1 267.3 241.7 259.8 145.9 244.8 414.8 364.5 380.7 303.4 339.9 407.2 208.8 290.8 173.4 155.5 391.5 296.1 408.8 401.5 411.4 183.7 149.7 542.4 252.5 347.8 212.7 306.8 186.4 292.1 269.7 261.2 268.6 245.2 230.0 82.5 338.7 140.2 265.1 292.7 218.9 264.0 229.3 276.5 339.7 281.5 623.8 164.6 103.0 149.2 259.8 346.1 332.2 201.0 179.6 411.5 190.5 118.3 178.1 170.9 323.1 128.0 200.7 327.0 185.7 507.4 107.3 144.4 429.1 246.9 110.5 369.5 142.7 179.9 145.6 134.6 382.1 149.8 149.5 134.0 239.9 132.8 333.9 214.8 205.7 510.2 92.4 92.6 101.3 116.0 95.2 104.5 97.2 97.1 99.0 100.4 98.6 102.7 61.4 48.1 74.5 14.4 65.1 69.8 117.8 274.0 81.4 27.5 145.2 105.2 236.5 131.5 119.0 147.1 10.4 328.4 50.6 84.5 1060.4 124.5 5.0 105.1 76.0 78.3 110.9 132.8 15.4 75.1 212.0 100.8 116.7 77.3 52.6 131.0 73.2 390.0 247.6 40.4 15.4 132.5 221.8 164.2 96.0 10.5 77.3 127.9 133.4 10.3 158.4 76.9 39.1 12.5 18.8 63.8 99.3 101.2 153.7 95.1 176.1 937.8 163.4 24.8 72.3 63.1 105.3 11.2 23.2 146.4 52.6 155.0 56.1 440.0 207.0 119.6 PRPF19 "hPSO4, NMP200, PRP19, PSO4, SNEV, UBOX4" ENSG00000110107 "Pre-mRNA processing factor 19" Q9UMS4 11 60890547-60906585 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012448, HPA038051, HPA059070" Supported Enhanced "Nuclear speckles" NA NA 71000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB012448: AB_2170868, HPA038051: AB_2675807, HPA059070: AB_2683896" "unprognostic (5.73e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (4.11e-8)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (9.37e-3)" "unprognostic (9.53e-2)" "unprognostic (1.54e-1)" "unprognostic (6.70e-2)" "unprognostic (9.62e-2)" "unprognostic (7.12e-2)" "unprognostic (9.04e-2)" "unprognostic (3.41e-3)" 46.1 70.6 89.8 49.8 87.9 67.0 48.8 73.7 100.2 57.4 60.2 54.5 42.9 55.4 34.2 81.7 57.3 29.4 47.9 91.3 94.1 50.4 77.2 34.6 64.1 92.0 80.7 66.6 69.4 79.8 79.3 42.9 92.9 62.1 51.8 46.1 56.5 48.2 75.2 80.3 49.5 47.9 75.6 54.3 54.3 30.5 81.1 78.5 43.4 38.9 73.7 58.7 55.9 84.5 197.5 147.0 161.8 116.2 92.7 80.8 155.6 102.4 137.5 200.2 149.0 162.7 141.1 280.5 145.2 98.2 120.2 179.0 229.2 184.6 153.4 207.0 153.4 232.4 111.3 184.9 134.2 308.6 161.1 86.3 137.0 154.4 171.9 58.7 158.7 167.4 248.2 155.3 99.5 270.6 328.9 249.5 292.6 150.5 197.7 285.8 165.5 227.5 101.7 127.5 142.3 172.9 126.6 208.3 178.0 73.1 225.8 170.2 101.9 89.6 147.2 161.8 171.2 147.2 223.3 287.9 111.6 208.6 138.6 4.2 7.8 2.0 2.4 3.8 1.7 0.9 1.8 1.7 3.6 2.4 2.2 2.0 0.5 1.8 2.3 3.9 1.7 1.0 89.8 87.9 73.7 100.2 91.3 94.1 92.0 80.7 92.9 75.6 81.1 84.5 15.8 19.2 23.7 10.1 26.7 42.1 35.2 40.2 33.0 32.0 24.6 19.4 17.6 20.0 28.6 27.6 10.4 94.7 16.2 20.4 27.4 48.5 21.6 21.4 19.7 27.3 39.0 45.2 19.8 51.6 90.2 24.9 23.4 28.4 22.8 25.4 20.0 46.1 46.3 62.2 22.2 40.0 32.6 23.0 21.6 3.6 37.0 19.3 26.6 11.2 41.2 25.4 21.6 10.1 11.8 33.4 27.7 38.7 31.9 40.4 27.8 27.9 17.8 25.3 46.0 22.4 22.6 25.2 38.0 37.4 41.6 40.6 24.8 24.8 55.1 26.3 PRR16 DSC54 ENSG00000184838 "Proline rich 16" Q569H4 5 120464300-120687332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 30.4" "Group enriched" "Detected in many" 9 "Excitatory neurons: 171.6;Inhibitory neurons: 188.9" "Cancer enriched" "Detected in many" 5 "prostate cancer: 13.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 77.3;BJ hTERT+: 83.9;fHDF/TERT166: 102.1;HSkMC: 62.5;hTERT-RPE1: 103.0;LHCN-M2: 97.9;U-138 MG: 117.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049254 Approved Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Midbody, Cytosol" "HPA049254: AB_2680693" "unprognostic (1.71e-1)" "unprognostic (3.87e-2)" "unprognostic (3.45e-1)" "unprognostic (1.20e-1)" "unprognostic (6.61e-2)" "unprognostic (7.07e-2)" "unprognostic (1.53e-1)" "unprognostic (2.42e-2)" "unprognostic (8.33e-2)" "unprognostic (4.40e-2)" "unprognostic (2.76e-2)" "unprognostic (2.06e-1)" "unprognostic (2.54e-8)" "unprognostic (3.05e-2)" "unprognostic (9.13e-2)" "unprognostic (2.65e-1)" "unprognostic (2.38e-3)" 11.0 2.8 2.0 5.2 2.1 0.2 7.9 6.1 3.5 14.9 0.0 5.1 1.7 11.8 1.5 1.8 7.0 5.7 12.7 2.2 5.1 3.0 0.9 9.8 1.1 3.4 1.8 5.6 2.0 1.1 1.7 9.7 3.2 9.3 4.5 7.0 2.6 2.4 26.4 4.0 5.0 8.2 0.7 2.5 4.0 2.4 2.3 0.7 4.4 30.4 0.9 9.5 10.0 1.4 3.7 0.0 8.0 0.0 22.2 77.3 0.0 37.0 83.9 51.5 39.1 0.0 0.2 0.0 0.0 102.1 9.3 0.0 8.1 0.9 53.8 0.0 1.9 0.0 1.2 0.0 21.5 0.2 0.1 62.5 8.9 15.4 48.0 103.0 1.7 0.0 0.1 0.1 97.9 0.0 0.0 0.0 0.9 0.0 1.4 0.0 6.2 0.0 4.3 0.0 0.3 16.1 0.1 0.0 1.1 6.1 0.1 0.1 0.5 117.9 13.3 3.8 19.4 0.3 0.0 0.0 6.7 0.2 4.1 0.1 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.3 2.0 2.1 6.1 3.5 2.2 5.1 3.4 1.8 3.2 0.7 2.3 1.4 1.4 0.0 0.0 14.0 0.4 1.3 6.2 0.0 0.0 7.5 1.5 1.9 3.2 0.0 0.0 0.0 14.6 0.1 0.1 0.0 0.0 0.1 16.8 0.9 18.9 0.8 0.0 0.0 171.6 0.0 0.0 13.5 0.0 0.8 0.0 0.2 0.4 0.0 0.5 15.2 188.9 0.0 0.0 1.8 2.7 11.6 2.8 1.0 1.8 9.4 0.1 2.6 0.0 7.5 3.9 0.2 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.7 0.0 1.4 9.6 0.9 1.4 0.5 0.6 0.5 0.4 3.1 0.0 0.7 PSRC1 DDA3 ENSG00000134222 "Proline and serine rich coiled-coil 1" Q6PGN9 1 109279556-109283186 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 101.5;choroid plexus: 47.9;retina: 41.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 30.1;Oligodendrocytes: 95.2;Peritubular cells: 44.8;Rod photoreceptor cells: 71.0" "Cancer enriched" "Detected in all" 4 "glioma: 50.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 12.0" "Group enriched" "Detected in many" 11 "dendritic cells: 5.4;granulocytes: 7.1;monocytes: 12.0" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 3.5;cerebral cortex: 7.7;hippocampal formation: 5.7;white matter: 3.4" "Low region specificity" "Detected in all" HPA056561 Supported Nucleoplasm,Cytosol NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Nucleoplasm "HPA056561: AB_2683175" "unprognostic (1.14e-1)" "unprognostic (1.65e-1)" "unprognostic (1.42e-3)" "unprognostic (6.78e-3)" "unprognostic (2.17e-1)" "unprognostic (4.76e-2)" "prognostic unfavorable (1.36e-9)" "unprognostic (3.51e-2)" "unprognostic (6.21e-2)" "unprognostic (4.88e-3)" "unprognostic (1.76e-2)" "unprognostic (1.92e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.43e-2)" "unprognostic (2.08e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-1)" 2.0 1.9 64.7 3.8 84.0 7.9 2.4 76.5 84.1 5.1 47.9 3.9 4.3 3.1 2.6 7.6 3.5 3.0 3.0 69.7 71.2 2.7 4.5 5.3 3.6 78.0 79.9 3.3 1.5 3.2 4.2 4.0 83.0 5.5 2.7 41.6 2.4 4.5 0.9 5.2 4.5 3.9 67.9 3.9 3.4 13.3 74.1 14.2 2.3 0.9 4.3 3.2 5.8 101.5 56.0 28.2 112.9 55.1 4.4 8.7 31.0 43.1 34.7 57.6 55.1 43.7 22.7 28.2 15.4 21.4 27.1 38.9 61.4 35.4 48.1 11.0 29.6 17.7 40.5 36.2 5.0 19.0 19.3 10.0 3.3 22.8 16.2 21.5 28.7 32.9 40.9 12.5 46.8 50.5 29.2 12.9 46.9 25.4 31.8 44.4 108.7 9.5 19.6 14.4 47.2 27.3 24.3 36.8 43.6 40.8 22.3 18.0 14.9 35.4 57.9 25.1 72.5 9.7 6.9 9.8 28.6 44.9 100.9 0.0 12.0 1.9 0.6 4.8 0.4 0.0 0.7 0.2 5.4 0.0 0.4 0.3 7.1 0.3 2.7 0.0 0.7 3.4 64.7 84.0 76.5 84.1 69.7 71.2 78.0 79.9 83.0 67.9 74.1 101.5 0.7 0.0 3.9 9.8 0.5 2.0 1.8 2.3 0.6 6.7 2.1 5.6 1.3 1.5 0.5 1.8 25.0 17.6 1.0 2.0 0.0 0.9 1.1 0.5 3.2 2.3 0.0 0.8 19.3 0.9 30.1 4.4 0.5 1.1 1.3 12.9 2.9 1.2 10.9 3.3 3.8 3.9 4.1 4.4 1.8 2.6 5.9 4.9 1.8 2.8 2.2 10.0 0.0 18.1 95.2 0.5 0.6 44.8 0.6 1.0 0.6 2.9 0.9 71.0 0.0 5.5 4.7 5.0 1.5 6.5 1.1 2.9 1.5 1.1 5.4 1.3 PTTG1IP "C21orf1, C21orf3, PBF" ENSG00000183255 "PTTG1 interacting protein" P53801 21 44849585-44873903 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034146, HPA061827" Uncertain Supported Nucleoplasm NA Yes 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB034146: AB_1568894, HPA061827: AB_2684620" "unprognostic (1.78e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (5.24e-3)" "unprognostic (3.18e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-2)" "unprognostic (3.59e-2)" "unprognostic (1.22e-2)" "unprognostic (1.98e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (9.30e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (5.40e-4)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.90e-1)" 127.8 131.8 147.6 98.4 158.9 92.0 114.0 150.8 146.8 131.1 131.1 132.7 123.2 132.4 118.5 89.1 109.4 141.8 164.3 138.1 168.7 157.6 130.5 160.5 75.3 178.8 152.9 110.7 85.6 84.1 68.8 180.1 169.9 108.5 111.5 29.7 118.3 151.4 70.7 88.9 127.3 145.0 152.0 97.7 169.9 66.9 175.3 57.9 127.4 63.2 62.0 139.6 93.3 157.5 245.3 134.6 155.3 148.2 300.6 174.8 127.0 212.9 309.8 174.1 166.6 290.0 323.9 32.9 789.8 344.4 417.0 109.8 73.0 140.2 161.1 56.3 81.0 254.3 80.0 260.1 293.8 97.6 83.5 269.9 225.1 189.1 130.8 346.3 376.6 88.6 131.7 83.1 539.5 106.0 71.0 99.5 166.8 352.9 169.8 70.4 158.4 162.0 735.6 82.7 117.2 182.0 240.0 262.5 482.0 188.7 203.7 163.7 511.8 216.9 126.5 170.6 340.0 78.5 79.4 42.2 146.7 220.6 199.8 336.2 181.2 109.1 48.4 146.7 79.5 25.5 62.7 51.3 203.3 23.6 59.7 41.0 248.8 67.3 167.0 92.5 87.3 223.7 147.6 158.9 150.8 146.8 138.1 168.7 178.8 152.9 169.9 152.0 175.3 157.5 140.9 394.2 169.6 39.8 28.0 50.7 84.1 181.3 61.5 14.6 102.0 96.8 173.0 75.8 248.9 145.3 6.2 218.6 56.8 321.4 49.0 323.0 51.5 115.0 115.0 191.6 79.3 37.8 8.5 120.6 72.7 117.1 140.6 187.7 81.5 181.3 124.2 102.2 109.3 11.8 10.7 89.1 130.2 88.0 69.6 98.7 72.1 136.3 87.2 22.5 91.1 78.8 51.5 20.1 31.9 294.3 255.2 98.9 36.4 112.8 268.1 71.2 192.3 15.2 65.7 61.1 127.9 73.7 43.4 92.4 42.9 366.7 45.6 54.6 100.3 169.9 QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 1616.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1918.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 2600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA056243: AB_2683077" "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" 84.8 84.9 35.8 52.1 39.4 115.5 53.2 42.7 47.3 81.7 41.1 100.1 67.5 75.2 70.2 178.4 82.3 150.3 244.9 41.5 43.4 73.8 81.7 200.0 16.3 50.0 40.7 196.1 136.3 21.0 60.2 158.9 43.2 92.3 80.9 15.2 105.6 57.5 91.2 58.6 85.7 60.0 44.0 61.9 178.3 172.9 42.6 12.1 31.9 46.0 19.6 174.1 108.7 57.7 441.4 62.0 14.8 181.0 179.1 367.8 712.5 456.5 456.6 381.6 267.1 7.3 137.7 6.8 276.7 367.8 52.6 93.7 17.6 123.5 185.0 26.4 28.0 14.1 33.6 19.4 1918.6 48.6 129.2 197.9 55.5 408.0 484.3 499.9 569.4 32.1 20.2 66.3 255.3 76.4 10.4 89.7 49.4 302.6 174.6 19.7 33.0 11.8 63.1 123.6 51.9 52.6 133.8 179.8 91.9 32.2 33.0 226.3 678.3 473.8 187.5 322.0 392.9 48.3 84.4 12.2 180.9 153.9 146.0 16.2 53.1 20.6 14.0 29.9 10.2 5.4 9.1 9.6 39.2 3.2 8.1 8.0 40.2 16.9 28.6 8.0 11.5 28.6 35.8 39.4 42.7 47.3 41.5 43.4 50.0 40.7 43.2 44.0 42.6 57.7 36.6 57.7 101.6 8.5 7.7 13.8 27.4 81.2 7.4 11.5 86.2 47.9 48.3 51.5 112.5 71.7 25.0 19.5 10.7 138.1 0.0 230.4 49.2 49.2 19.4 41.7 46.2 6.9 17.2 130.1 1616.7 78.0 136.6 80.4 25.4 27.1 89.3 4.3 68.6 6.7 17.0 185.7 132.2 45.2 35.3 20.1 177.7 48.9 44.4 8.4 49.7 53.5 10.3 24.6 23.9 249.8 165.6 71.1 12.8 35.7 9.0 9.1 47.8 6.7 32.9 13.6 31.3 30.2 32.7 10.2 9.9 154.3 13.9 13.9 89.9 68.0 RAB20 FLJ20429 ENSG00000139832 "RAB20, member RAS oncogene family" Q9NX57 13 110523066-110561722 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 91.3;Hofbauer cells: 105.0;Kupffer cells: 92.1;Macrophages: 100.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 60.9;SK-BR-3: 85.7;T-47d: 54.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA002882, HPA052111, HPA068647" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "HPA002882: , HPA052111: AB_2681732, HPA068647: AB_2686013" "unprognostic (5.59e-3)" "unprognostic (1.30e-1)" "unprognostic (3.48e-1)" "unprognostic (1.42e-3)" "unprognostic (1.30e-1)" "unprognostic (3.82e-2)" "unprognostic (1.14e-2)" "unprognostic (5.99e-2)" "unprognostic (9.43e-2)" "unprognostic (2.06e-2)" "unprognostic (9.41e-2)" "unprognostic (2.65e-1)" "prognostic favorable (8.57e-4)" "unprognostic (6.96e-2)" "unprognostic (4.32e-2)" "unprognostic (2.28e-2)" "prognostic favorable (4.48e-4)" 31.1 55.4 5.7 21.7 5.5 25.3 23.4 5.6 7.9 11.7 9.6 20.7 27.6 6.9 4.8 4.6 11.5 18.0 21.4 5.2 7.0 26.1 51.4 30.7 16.4 7.0 6.0 20.5 24.2 6.2 9.7 22.8 6.8 12.1 14.3 2.6 10.7 5.0 5.8 4.6 25.3 7.6 6.6 44.5 28.6 10.6 7.4 3.9 22.0 2.3 5.1 20.6 6.7 8.4 20.1 2.9 1.9 3.8 12.4 3.3 31.3 1.7 6.2 8.1 12.5 47.9 39.9 0.0 13.9 1.7 10.8 7.5 3.8 12.3 4.2 22.5 3.0 19.8 3.6 22.6 7.8 2.8 5.7 6.9 2.0 4.2 1.2 6.3 3.1 3.3 3.8 0.0 1.8 24.0 0.1 29.0 4.0 60.9 8.5 1.9 0.1 9.0 14.2 26.3 0.5 2.1 3.8 85.7 27.4 6.2 54.4 30.5 2.3 2.0 4.2 0.2 2.7 0.1 0.0 0.2 27.7 38.9 4.2 7.8 35.5 7.1 1.0 33.3 1.3 3.5 2.8 0.9 15.8 2.8 6.5 2.3 26.3 0.0 26.6 0.8 0.9 11.2 5.7 5.5 5.6 7.9 5.2 7.0 7.0 6.0 6.8 6.6 7.4 8.4 18.6 19.2 20.4 4.2 10.6 4.5 10.9 14.1 10.8 0.2 12.8 13.0 5.0 48.6 16.2 25.8 0.0 34.6 1.8 31.1 31.3 60.3 1.6 20.7 2.6 10.3 18.0 0.0 0.4 67.9 91.3 11.5 15.3 23.2 21.0 41.1 53.6 34.5 105.0 0.0 0.4 23.9 28.5 92.1 19.9 1.6 3.7 100.5 7.2 8.4 16.2 7.4 0.0 4.5 0.1 36.4 17.2 6.4 0.4 8.0 48.1 68.9 20.4 2.0 13.1 6.2 26.2 1.0 13.2 1.9 3.0 20.0 3.6 7.2 24.0 11.1 RAB31 Rab22B ENSG00000168461 "RAB31, member RAS oncogene family" Q13636 18 9708275-9862551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 180.9;Kupffer cells: 283.8;Langerhans cells: 208.9;Macrophages: 221.6;monocytes: 193.2;Oligodendrocyte precursor cells: 184.0;Syncytiotrophoblasts: 186.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 137.9" "Group enriched" "Detected in many" 8 "dendritic cells: 44.9;granulocytes: 137.9;monocytes: 51.6" "Cell line enhanced" "Detected in many" "GAMG: 175.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019717 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "HPA019717: AB_10601493" "unprognostic (4.61e-2)" "unprognostic (1.65e-2)" "unprognostic (8.53e-2)" "unprognostic (1.13e-1)" "unprognostic (1.23e-2)" "unprognostic (5.70e-2)" "unprognostic (3.07e-2)" "unprognostic (5.99e-2)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (1.71e-2)" "unprognostic (1.75e-1)" "unprognostic (6.26e-2)" "unprognostic (3.98e-3)" "unprognostic (8.71e-3)" "unprognostic (1.61e-1)" "unprognostic (6.34e-2)" 35.0 104.8 83.1 42.2 90.5 59.7 22.2 89.1 92.6 85.2 67.7 45.8 11.1 56.2 9.4 31.8 28.8 45.6 20.9 75.9 93.1 16.3 10.5 58.9 22.4 96.6 95.1 44.2 7.0 8.6 10.0 56.5 96.8 21.3 17.7 12.6 13.7 48.7 5.4 12.9 23.7 85.8 91.5 31.3 31.7 42.6 99.3 9.8 25.9 10.5 22.6 54.5 35.2 92.1 2.7 14.4 105.0 0.2 136.7 70.5 74.6 25.4 71.0 18.2 15.8 4.1 14.4 0.1 16.6 99.7 175.3 9.9 25.9 32.6 21.1 6.5 14.6 89.3 104.4 1.8 158.0 7.4 94.2 76.5 6.6 42.1 32.5 78.0 47.4 0.0 22.2 0.4 42.6 11.9 0.1 11.5 22.2 1.2 6.3 0.1 11.5 3.7 13.9 0.3 2.0 6.8 96.4 60.7 34.7 87.5 6.9 48.4 51.9 112.9 56.4 78.3 37.5 19.4 5.7 0.1 153.7 0.1 47.1 137.9 51.6 21.3 0.1 47.2 0.1 9.8 0.2 0.1 44.9 6.7 0.1 0.1 74.4 4.3 50.2 5.2 0.2 19.5 83.1 90.5 89.1 92.6 75.9 93.1 96.6 95.1 96.8 91.5 99.3 92.1 10.0 176.3 33.3 91.4 32.4 15.8 17.7 30.8 23.3 3.2 13.2 12.6 10.6 12.8 51.2 11.0 0.0 180.9 11.0 8.7 7.9 7.9 5.4 10.2 86.0 33.1 0.0 2.5 8.1 19.6 19.0 55.5 5.6 6.2 7.6 72.9 30.0 1.9 157.0 151.4 19.6 0.6 8.2 283.8 208.9 10.9 17.7 221.6 7.2 75.9 193.2 21.5 4.1 184.0 7.0 19.4 1.4 117.4 12.0 27.3 0.0 4.0 47.0 3.9 39.5 14.0 87.3 1.7 4.2 14.5 16.1 186.6 5.1 36.3 0.3 38.8 RAB32 ENSG00000118508 "RAB32, member RAS oncogene family" Q13637 6 146543833-146554953 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 175.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 232.6;Kupffer cells: 254.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 86.5" "Group enriched" "Detected in many" 42 "dendritic cells: 42.5;granulocytes: 86.5;monocytes: 46.8" "Low cell line specificity" "Detected in many" HPA025731 Approved Approved Cytosol NA NA 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA025731: AB_1856001" "unprognostic (3.07e-1)" "unprognostic (5.32e-2)" "prognostic favorable (1.56e-4)" "prognostic unfavorable (6.51e-4)" "unprognostic (1.26e-1)" "unprognostic (2.34e-3)" "prognostic unfavorable (1.08e-7)" "unprognostic (2.64e-2)" "unprognostic (9.71e-2)" "unprognostic (3.38e-2)" "unprognostic (2.80e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.54e-1)" "unprognostic (6.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.67e-1)" 35.0 16.5 7.5 29.7 7.8 175.1 27.0 8.6 11.0 19.0 9.2 38.3 17.4 26.5 14.6 11.6 20.8 24.1 17.9 7.1 8.2 21.3 50.2 32.1 22.3 9.9 8.2 13.0 12.2 8.3 5.0 14.8 8.9 14.5 37.7 2.2 18.1 16.9 4.6 20.2 18.4 46.5 9.2 54.1 19.4 33.3 8.8 22.5 11.0 8.3 15.2 28.6 15.4 11.7 65.5 34.5 38.7 65.3 58.0 98.5 0.1 123.3 138.4 167.7 276.7 21.2 31.6 0.1 43.9 132.2 183.5 84.2 2.4 80.4 225.2 0.4 29.1 82.4 78.3 77.3 252.1 114.2 115.9 87.6 133.1 95.8 135.3 86.7 110.5 0.0 15.8 0.4 92.8 15.8 52.0 61.8 5.0 0.0 65.2 0.0 41.5 0.9 65.6 45.2 0.1 50.6 144.7 17.6 219.3 34.3 33.7 91.7 88.0 50.2 67.7 133.1 152.6 0.2 9.4 0.4 115.1 86.0 69.3 86.5 46.8 8.2 0.0 21.2 0.0 0.0 0.0 0.1 42.5 0.0 0.1 0.0 16.5 1.3 15.4 2.2 0.0 14.4 7.5 7.8 8.6 11.0 7.1 8.2 9.9 8.2 8.9 9.2 8.8 11.7 30.8 48.1 9.4 2.9 4.1 53.5 95.3 92.6 17.6 1.4 29.0 38.9 2.0 52.9 36.8 11.0 4.2 2.2 3.4 64.1 25.4 164.4 96.9 8.5 40.3 34.3 60.1 14.9 2.3 105.7 6.9 51.5 18.3 12.4 57.8 27.7 27.5 75.4 232.6 0.0 1.3 31.3 22.4 254.6 101.7 156.7 24.5 146.7 168.9 24.4 147.2 9.0 2.1 4.0 4.6 154.3 46.3 25.6 0.5 99.6 33.3 83.2 9.5 1.4 19.7 46.1 46.3 70.9 14.2 2.5 19.0 3.1 7.0 33.1 62.5 65.6 RAB9A RAB9 ENSG00000123595 "RAB9A, member RAS oncogene family" P51151 X 13689128-13710504 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 345.3;Syncytiotrophoblasts: 370.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003094, CAB016411" Supported Uncertain Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "CAB016411: AB_630176, HPA003094: AB_1079736" "unprognostic (3.40e-2)" "unprognostic (1.36e-2)" "unprognostic (3.56e-3)" "unprognostic (3.08e-2)" "unprognostic (1.62e-1)" "unprognostic (2.56e-2)" "unprognostic (1.79e-2)" "unprognostic (1.45e-1)" "unprognostic (8.77e-2)" "unprognostic (8.23e-2)" "unprognostic (1.27e-2)" "unprognostic (4.88e-2)" "prognostic favorable (3.35e-5)" "unprognostic (3.93e-2)" "unprognostic (3.19e-1)" "unprognostic (1.46e-1)" "unprognostic (2.68e-2)" 28.9 51.7 24.2 18.4 27.2 56.0 32.8 28.3 28.2 31.4 21.8 28.4 14.9 29.4 21.3 29.7 21.5 22.8 20.7 23.4 26.0 30.3 24.9 24.9 25.1 28.0 25.3 28.2 33.2 38.1 15.5 28.7 28.7 20.2 25.0 21.7 37.0 18.9 19.7 37.0 19.1 22.1 28.5 22.0 21.4 7.6 25.0 16.5 21.1 16.5 31.7 27.4 27.9 32.1 34.8 18.1 22.9 54.5 75.1 59.7 20.4 19.0 66.4 28.5 41.2 19.6 37.7 31.3 45.7 29.9 68.1 34.8 34.4 40.4 27.8 69.6 53.4 9.9 36.6 22.9 45.0 17.7 25.8 64.6 69.5 35.8 38.2 45.7 26.8 17.3 19.5 44.8 30.9 23.9 16.8 28.8 24.7 24.0 34.1 22.7 24.2 94.7 78.8 31.7 18.8 13.2 40.3 56.3 69.3 56.8 31.4 18.5 21.1 21.5 11.2 76.9 11.6 35.4 66.4 12.8 21.5 15.1 21.5 34.1 37.7 17.5 38.1 25.3 29.9 20.0 20.7 31.9 26.5 14.2 15.3 26.3 22.5 31.0 24.1 29.1 18.0 22.0 24.2 27.2 28.3 28.2 23.4 26.0 28.0 25.3 28.7 28.5 25.0 32.1 25.4 48.1 27.3 19.9 35.0 64.7 69.0 73.4 29.6 8.7 35.9 39.0 16.6 42.9 64.1 33.1 0.0 83.6 121.0 85.3 80.3 135.0 0.6 78.8 46.2 23.7 24.5 27.8 11.1 64.0 60.5 39.2 23.4 105.8 45.1 13.5 14.3 19.2 54.9 15.2 13.7 32.2 52.9 45.0 104.9 2.2 37.6 46.7 56.9 6.5 345.3 50.9 68.0 33.7 36.6 81.1 103.1 40.3 53.8 93.1 30.7 68.9 42.8 9.4 13.1 28.1 37.2 9.7 17.7 44.5 83.4 370.4 75.6 51.4 26.6 111.8 RASSF4 "AD037, MGC44914" ENSG00000107551 "Ras association domain family member 4" Q9H2L5 10 44959407-44995891 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 77.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.0;monocytes: 258.7;Muller glia cells: 260.3;Proximal tubular cells: 128.0;Skeletal myocytes: 186.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 84.8;intermediate monocyte: 63.9;myeloid DC: 84.2;non-classical monocyte: 37.9" "Group enriched" "Detected in many" 10 "dendritic cells: 84.2;monocytes: 84.8" "Cell line enhanced" "Detected in many" "Karpas-707: 64.3;RH-30: 162.7;RPMI-8226: 54.9;U-937: 85.4;WM-115: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038834, HPA077069" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA038834: AB_10795576, HPA077069: " "unprognostic (1.83e-1)" "unprognostic (8.21e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (5.14e-2)" "unprognostic (3.15e-2)" "unprognostic (2.18e-2)" "unprognostic (8.81e-2)" "unprognostic (4.83e-2)" "unprognostic (8.75e-3)" "unprognostic (4.20e-1)" "unprognostic (4.11e-3)" "unprognostic (4.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.42e-1)" "unprognostic (6.20e-2)" 35.3 7.1 57.4 21.7 67.9 8.3 22.7 64.3 58.6 6.5 43.8 18.5 13.6 3.0 8.6 4.7 6.0 10.8 44.8 53.9 58.9 77.3 17.1 11.9 19.7 63.4 64.0 3.6 39.5 5.0 13.0 12.7 65.9 7.9 6.0 26.9 16.7 10.9 14.8 4.8 13.8 8.7 55.8 20.1 9.4 9.0 65.3 10.4 40.7 17.6 9.1 11.4 7.0 69.7 1.4 0.3 6.0 11.4 17.9 1.0 4.1 0.7 1.1 2.0 3.5 5.0 0.6 0.1 2.3 0.8 3.9 0.0 2.6 2.8 2.8 37.8 0.0 0.1 0.2 39.7 19.0 2.6 0.0 13.1 0.0 1.9 0.2 10.9 3.0 1.6 0.0 64.3 2.9 0.0 3.0 43.1 1.2 0.2 1.2 8.1 162.7 54.9 0.4 1.2 1.0 0.8 0.0 0.5 2.0 10.7 1.1 32.4 0.0 0.4 3.6 3.0 6.5 0.7 0.7 0.1 18.9 85.4 54.8 0.0 84.8 0.1 8.7 63.9 0.2 0.0 0.6 3.7 84.2 0.0 0.6 2.6 3.0 6.9 37.9 2.2 0.3 48.9 57.4 67.9 64.3 58.6 53.9 58.9 63.4 64.0 65.9 55.8 65.3 69.7 8.9 19.2 17.2 77.4 3.7 3.7 1.4 3.2 1.2 22.5 9.7 7.0 47.9 37.1 13.1 16.5 4.2 1.2 20.3 10.1 17.6 45.3 1.4 6.4 13.7 9.2 11.5 0.0 17.0 3.8 1.2 28.6 1.5 14.8 1.3 4.2 6.1 20.1 157.0 37.0 33.6 7.4 12.2 84.7 94.3 4.4 10.5 91.0 8.8 35.6 258.7 260.3 54.6 37.7 38.2 4.0 11.3 2.2 4.1 1.0 45.0 128.0 5.9 13.3 26.3 186.4 25.9 0.6 1.9 0.8 1.7 2.6 8.0 4.9 15.0 0.7 RBMS2 SCR3 ENSG00000076067 "RNA binding motif single stranded interacting protein 2" Q15434 12 56521820-56596193 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039225, HPA058784" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA039225: AB_10963056, HPA058784: AB_2683819" "unprognostic (1.35e-1)" "unprognostic (5.31e-2)" "unprognostic (2.61e-1)" "unprognostic (5.29e-2)" "unprognostic (9.09e-2)" "unprognostic (3.19e-3)" "unprognostic (4.78e-2)" "unprognostic (1.89e-2)" "unprognostic (7.01e-2)" "unprognostic (2.80e-1)" "unprognostic (2.86e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.22e-4)" "unprognostic (2.67e-2)" "unprognostic (4.73e-2)" "unprognostic (4.06e-3)" "unprognostic (2.63e-2)" 19.4 7.1 12.5 5.7 11.5 3.6 17.4 9.3 13.1 14.7 15.1 12.9 4.7 13.7 9.3 8.2 13.7 9.5 15.6 9.2 10.0 14.7 3.4 37.3 3.2 14.5 11.7 12.6 7.0 8.6 6.1 23.5 13.4 11.2 8.8 6.0 10.1 8.7 8.4 8.3 9.0 12.1 9.8 10.5 8.5 4.3 15.2 3.5 18.3 10.8 3.9 10.3 13.9 11.7 28.8 24.3 10.5 14.9 23.7 22.7 9.3 34.8 37.0 26.9 23.9 18.7 50.2 0.2 42.1 36.6 11.1 20.4 7.8 57.8 30.1 8.3 6.7 3.7 19.0 4.8 15.4 3.8 6.5 20.9 13.9 28.1 33.5 31.4 51.1 6.1 1.8 6.5 47.0 3.7 4.1 4.9 6.2 0.0 7.5 2.4 11.5 0.3 34.1 6.4 0.8 6.9 39.6 14.9 5.1 22.2 16.0 6.3 78.2 16.7 35.8 9.5 8.4 6.1 2.5 1.7 6.1 0.9 23.6 0.6 4.7 1.6 0.8 1.3 0.9 0.3 0.3 1.2 2.7 0.5 0.9 0.6 1.6 1.0 0.3 0.6 0.5 0.8 12.5 11.5 9.3 13.1 9.2 10.0 14.5 11.7 13.4 9.8 15.2 11.7 74.4 41.7 20.5 34.6 1.5 3.7 9.7 6.8 11.4 4.2 11.4 9.4 7.9 12.8 14.2 12.9 10.4 19.8 7.0 19.7 1.9 23.6 12.6 16.4 16.9 47.9 5.4 3.2 7.2 16.9 38.5 16.9 6.1 21.8 8.2 10.4 52.1 1.0 10.5 8.4 10.0 5.9 4.1 22.7 5.5 24.2 17.4 11.2 0.0 53.4 6.2 5.4 4.1 30.7 9.6 37.8 11.5 24.8 0.8 13.4 1.6 13.4 6.8 1.7 26.3 11.2 15.5 0.9 1.8 5.4 2.0 23.7 2.5 8.7 7.0 17.3 RBP7 CRBPIV ENSG00000162444 "Retinol binding protein 7" Q96R05 1 9997206-10016021 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 401.0;breast: 394.6" "Cell type enriched" "Detected in many" 7 "Adipocytes: 3631.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 311.5;neutrophil: 344.7" "Group enriched" "Detected in many" 31 "granulocytes: 344.7;monocytes: 311.5" "Group enriched" "Detected in some" 4 "EFO-21: 13.0;SK-MEL-30: 9.8;T-47d: 34.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA034749 Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Cytosol" "HPA034749: AB_10602084" "unprognostic (1.93e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (9.59e-2)" "unprognostic (2.31e-1)" "unprognostic (6.28e-2)" "unprognostic (1.39e-2)" "unprognostic (1.85e-1)" "unprognostic (1.05e-3)" "unprognostic (2.24e-1)" "unprognostic (1.46e-2)" "unprognostic (7.90e-2)" "unprognostic (5.07e-2)" "unprognostic (2.38e-2)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (1.61e-2)" 401.0 15.0 20.7 8.9 27.0 28.6 394.6 23.8 38.3 22.6 23.4 15.0 2.6 20.4 4.2 34.4 14.7 51.6 86.6 20.4 22.4 72.9 9.6 8.8 8.3 23.7 24.0 12.7 11.9 68.9 16.7 15.9 23.7 18.6 4.4 5.0 22.3 8.1 16.0 35.4 11.5 14.9 23.5 112.1 17.2 9.2 22.4 12.6 36.2 24.9 5.6 23.6 27.9 36.4 0.0 0.6 0.3 0.0 0.0 0.5 0.0 0.0 0.0 2.5 0.9 2.5 3.2 0.0 13.0 1.3 0.0 0.0 0.1 1.0 4.4 0.0 2.8 0.0 0.1 1.3 1.6 0.0 0.0 0.0 2.0 2.1 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 3.4 0.0 0.0 0.0 0.7 0.0 0.2 0.5 2.6 0.2 9.8 3.5 34.8 2.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 311.5 2.8 0.4 138.4 0.2 0.1 0.0 0.1 10.6 0.2 0.2 0.1 344.7 0.0 68.3 2.0 0.7 96.8 20.7 27.0 23.8 38.3 20.4 22.4 23.7 24.0 23.7 23.5 22.4 36.4 3631.8 0.0 1.3 0.7 9.5 20.6 9.5 2.6 9.1 0.2 43.0 73.9 22.9 10.0 1.2 1.8 0.0 5.0 16.2 0.1 23.5 2.0 3.2 2.5 15.8 349.2 0.0 5.7 0.4 2.8 1.9 36.1 0.0 4.8 3.8 7.1 69.7 3.7 63.7 0.0 0.4 0.4 2.0 502.5 14.1 6.1 6.2 42.5 21.4 1.0 149.7 2.1 3.1 0.0 13.4 2.7 0.1 0.7 2.7 20.7 0.0 1.4 0.9 1.5 0.0 3.9 20.5 1.8 2.8 26.2 17.6 6.2 3.8 3.6 0.6 6.3 RCBTB2 CHC1L ENSG00000136161 "RCC1 and BTB domain containing protein 2" O95199 13 48488963-48533256 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 9 "MOLT-4: 278.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040242 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Golgi apparatus" "HPA040242: AB_10795362" "unprognostic (2.86e-1)" "unprognostic (5.93e-2)" "unprognostic (8.47e-2)" "unprognostic (9.47e-3)" "unprognostic (1.60e-1)" "unprognostic (1.86e-3)" "unprognostic (1.29e-1)" "unprognostic (5.40e-3)" "unprognostic (8.28e-3)" "unprognostic (1.20e-1)" "unprognostic (4.85e-2)" "unprognostic (3.60e-1)" "prognostic favorable (2.45e-4)" "unprognostic (1.06e-2)" "unprognostic (8.31e-2)" "unprognostic (4.75e-2)" "unprognostic (1.98e-1)" 12.9 11.1 10.0 12.9 11.2 5.2 10.8 11.1 13.9 15.6 17.4 8.9 5.3 15.0 12.3 13.0 12.9 12.3 12.5 9.5 13.2 16.6 9.5 10.5 11.3 11.9 11.7 19.9 6.8 6.6 13.4 17.7 12.5 13.5 8.0 8.3 23.3 19.9 7.0 5.4 7.2 13.7 13.0 17.4 8.8 7.1 10.8 11.8 27.5 10.8 10.7 11.5 12.4 14.4 1.5 1.2 22.0 1.4 17.1 15.1 0.0 6.8 8.4 4.0 3.0 0.8 1.4 4.7 5.0 10.7 2.7 3.1 3.2 2.8 4.6 5.7 4.3 12.2 3.2 1.2 6.6 5.6 7.4 15.6 6.5 5.3 2.6 9.2 12.3 29.8 0.9 7.1 14.6 0.5 278.7 15.6 12.3 0.5 3.7 23.9 2.2 20.3 7.5 3.7 5.1 4.3 5.3 1.1 8.7 9.1 0.5 14.2 10.3 4.6 2.0 1.2 2.7 0.3 0.4 5.7 2.7 12.5 9.1 4.6 39.8 4.6 14.0 28.8 8.7 1.1 11.4 14.2 27.1 1.1 6.6 10.2 55.0 15.5 27.9 0.5 15.5 20.5 10.0 11.2 11.1 13.9 9.5 13.2 11.9 11.7 12.5 13.0 10.8 14.4 23.1 3.2 3.3 9.1 5.5 6.1 11.6 9.5 21.1 1.9 4.9 9.3 16.1 4.3 9.8 5.5 2.1 1.4 20.7 1.3 7.9 1.2 9.0 5.1 6.6 19.7 8.3 6.1 12.3 0.8 1.4 11.6 2.6 5.0 8.8 9.9 24.7 5.2 25.0 1.7 17.0 2.2 2.0 26.6 24.4 8.1 9.3 30.6 8.8 66.5 38.3 33.7 24.7 6.6 13.2 1.3 1.6 14.3 17.4 6.0 0.7 11.2 6.9 4.9 13.1 14.9 14.1 9.6 4.4 12.6 5.7 1.0 24.0 11.9 2.4 6.7 RETN "ADSF, FIZZ3, RETN1" ENSG00000104918 Resistin Q9HD89 19 7669049-7670455 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Hormone "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 247.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 118.2;Kupffer cells: 47.0;Macrophages: 90.4;monocytes: 58.2" "Group enriched" "Detected in many" 4 "lung cancer: 2.6;pancreatic cancer: 4.8;thyroid cancer: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "classical monocyte: 170.4;intermediate monocyte: 91.7;myeloid DC: 118.7;non-classical monocyte: 47.4" "Group enriched" "Detected in many" 11 "dendritic cells: 118.7;monocytes: 170.4" "Group enriched" "Detected in some" 11 "NB-4: 524.3;U-937: 243.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 5120000 1200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.61e-2)" "unprognostic (6.20e-3)" "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (5.19e-4)" "unprognostic (1.53e-4)" "unprognostic (7.34e-2)" "unprognostic (3.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (4.02e-1)" "unprognostic (7.16e-5)" "unprognostic (4.23e-2)" "unprognostic (2.26e-1)" "unprognostic (8.91e-2)" "unprognostic (1.20e-1)" 3.4 1.0 0.1 5.2 0.1 247.2 1.4 0.0 0.9 0.6 0.0 0.8 6.1 0.7 0.0 0.5 2.4 0.3 2.3 0.4 0.1 1.7 3.3 34.0 0.1 0.1 0.1 0.4 0.9 0.1 0.5 1.1 0.1 1.0 0.2 0.0 1.1 0.0 0.6 0.7 0.7 4.3 0.0 53.3 1.0 0.2 0.0 4.0 0.8 0.0 0.0 0.6 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.7 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.9 524.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 243.2 0.0 0.1 170.4 0.1 0.4 91.7 1.2 0.0 1.9 1.5 118.7 0.1 4.4 9.0 13.6 0.3 47.4 4.5 0.0 64.3 0.1 0.1 0.0 0.9 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 12.8 9.9 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 1.1 0.6 0.0 0.0 3.8 0.0 0.4 0.1 118.2 0.0 0.0 0.0 0.0 47.0 8.7 0.2 0.0 90.4 0.0 0.0 58.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 2.2 0.0 0.0 0.1 RFPL4A "RFPL4, RNF210" ENSG00000223638 "Ret finger protein like 4A" A6NLU0 19 55759014-55763175 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.4;liver: 3.4;testis: 1.6" "Cell type enhanced" "Detected in some" "Early spermatids: 1.1;Langerhans cells: 1.4" "Cancer enriched" "Detected in single" 6 "testis cancer: 0.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7" "Group enriched" "Detected in many" 4 "dendritic cells: 3.1;monocytes: 9.7" "Cell line enriched" "Detected in some" 20 "U-2 OS: 68.4" HPA046368 Uncertain Approved Centrosome,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 9: U-2 OS - Unknown function" "Cluster 41: Macrophages - Immune response" "Centrosome, Cytosol" "HPA046368: AB_2679640" "unprognostic (3.74e-1)" "unprognostic (2.96e-2)" "unprognostic (9.20e-2)" 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 3.4 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.2 1.6 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.3 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 68.4 0.0 0.2 0.4 0.4 0.2 0.0 0.0 0.0 0.0 9.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 1.4 0.0 0.7 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.1 0.3 0.0 0.0 0.0 0.0 RFPL4AL1 RNF210B ENSG00000229292 "Ret finger protein like 4A like 1" F8VTS6 19 55769118-55773420 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.5" "Group enriched" "Detected in many" 5 "dendritic cells: 1.3;monocytes: 3.5" "Cell line enriched" "Detected in some" 19 "U-2 OS: 40.2" HPA046368 Uncertain Approved Centrosome,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 9: U-2 OS - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Centrosome, Cytosol" "HPA046368: AB_2679640" "unprognostic (8.87e-2)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RILP FLJ31193 ENSG00000167705 "Rab interacting lysosomal protein" Q96NA2 17 1646145-1649866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 60.5;skeletal muscle: 48.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.4;Proximal enterocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.5;eosinophil: 1.0;intermediate monocyte: 1.2;myeloid DC: 2.4;neutrophil: 3.3;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.3;monocytes: 3.5" "Cell line enhanced" "Detected in many" "HEL: 40.6;HMC-1: 19.5;K-562: 15.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA 18000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" "prognostic favorable (7.97e-4)" "unprognostic (7.93e-2)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-2)" "unprognostic (8.84e-3)" "unprognostic (1.61e-1)" "unprognostic (2.64e-1)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "prognostic favorable (8.51e-5)" "unprognostic (2.26e-1)" "unprognostic (4.73e-2)" "unprognostic (1.00e-1)" "prognostic favorable (7.12e-4)" 17.4 18.0 3.4 0.8 3.3 8.1 15.6 3.2 5.1 5.0 10.7 15.5 10.5 5.9 0.6 5.4 6.9 1.1 60.5 3.1 3.3 15.3 29.1 13.1 1.0 3.7 3.4 3.2 10.4 1.8 4.5 0.8 3.4 6.0 1.4 0.4 11.5 1.2 48.1 6.3 13.0 0.9 2.9 15.1 13.5 3.2 3.8 0.3 29.6 8.3 0.4 11.3 5.1 3.2 2.3 1.6 0.2 1.7 1.1 2.7 7.7 1.5 1.0 1.6 0.9 3.6 0.5 0.4 5.2 1.2 0.5 5.5 0.2 0.2 0.3 0.2 3.6 40.6 0.5 4.6 1.7 0.3 19.5 2.2 0.7 0.4 0.0 0.8 1.4 0.3 15.8 0.4 0.5 2.2 1.4 3.1 0.4 0.4 8.1 5.8 0.0 1.1 0.0 1.3 0.1 0.6 0.8 1.0 2.0 0.2 1.0 0.3 7.8 0.5 1.0 1.9 1.5 0.3 0.5 0.0 3.0 1.8 0.3 0.3 3.5 1.0 0.1 1.2 0.1 0.3 0.2 0.1 2.4 0.0 0.2 0.0 3.3 0.5 0.2 1.3 0.1 0.7 3.4 3.3 3.2 5.1 3.1 3.3 3.7 3.4 3.4 2.9 3.8 3.2 42.6 19.2 17.7 3.3 3.2 8.8 13.3 7.5 2.8 1.6 11.1 13.1 59.9 17.2 8.9 7.3 0.0 15.8 12.1 101.4 50.9 29.2 0.1 3.2 5.1 21.9 3.0 65.9 3.1 25.4 9.4 12.9 24.5 5.1 0.0 2.1 26.0 30.6 57.1 3.3 2.4 27.6 8.2 35.2 34.3 2.6 6.8 34.1 14.2 5.6 28.1 9.9 5.2 2.0 1.3 20.2 59.7 8.2 10.3 8.4 84.9 20.8 3.1 1.3 13.1 8.3 9.2 0.6 12.2 7.4 8.2 34.6 5.2 9.4 28.7 21.0 RNASE4 RAB1 ENSG00000258818 "Ribonuclease A family member 4" P34096 14 20684560-20701216 "Plasma proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 478.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 67.3;Gastric mucus-secreting cells: 47.4;Hepatocytes: 55.8;Intestinal goblet cells: 110.0" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 92.6;ASC TERT1: 107.2;Hep G2: 136.9;HSkMC: 63.1;OE19: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 61000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 27: Mucus-secreting cells - Mucin production" "unprognostic (1.07e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-2)" "unprognostic (3.18e-4)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "prognostic favorable (9.62e-5)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (6.88e-2)" "unprognostic (3.71e-2)" "unprognostic (1.29e-1)" "unprognostic (3.46e-1)" "unprognostic (2.54e-2)" "unprognostic (1.57e-1)" "unprognostic (9.16e-2)" "unprognostic (4.27e-2)" 106.4 7.8 5.5 8.9 5.7 1.2 96.6 5.4 8.3 95.6 8.5 56.5 22.0 59.2 37.0 20.1 77.3 55.6 44.1 5.5 8.1 40.3 478.8 40.3 12.2 6.9 6.6 111.7 41.0 14.7 12.5 5.7 6.9 76.7 65.2 4.7 74.8 45.8 14.1 47.4 41.9 25.9 6.7 11.8 84.7 10.6 5.3 5.8 26.5 31.5 10.6 65.3 75.9 7.8 2.7 12.1 2.6 0.1 92.6 107.2 0.5 10.5 23.8 1.4 4.5 3.4 4.1 0.1 2.9 24.6 6.2 2.5 1.4 2.6 1.7 17.2 1.8 0.3 2.9 136.9 10.2 1.3 0.6 63.1 5.8 1.6 10.3 34.6 12.6 4.2 0.1 12.2 6.9 1.5 1.0 0.2 0.5 92.3 10.3 0.6 2.1 3.6 2.9 2.4 0.1 0.5 5.0 2.3 2.6 4.2 3.4 0.2 13.3 3.0 1.7 4.1 0.3 2.6 3.5 0.4 4.7 1.3 2.7 0.2 24.1 0.1 0.8 1.2 1.0 5.3 1.5 0.6 13.8 4.9 0.3 0.6 0.6 0.6 0.1 3.3 3.3 8.4 5.5 5.7 5.4 8.3 5.5 8.1 6.9 6.6 6.9 6.7 5.3 7.8 1.8 38.5 19.1 2.0 3.4 2.8 1.7 2.5 11.4 0.0 9.9 2.5 0.2 28.6 4.7 3.7 0.0 0.2 0.3 30.4 0.0 34.4 0.2 0.1 0.8 4.0 67.3 8.4 0.1 22.2 0.4 39.2 47.4 0.8 1.3 0.3 5.0 55.8 1.6 0.0 0.2 110.0 2.0 6.2 4.0 0.3 12.5 3.6 3.6 1.9 2.7 1.3 1.0 0.0 0.9 12.8 33.2 4.1 5.9 1.7 41.7 10.2 11.6 0.3 0.0 2.6 8.1 0.2 0.1 10.2 4.1 0.4 0.8 0.1 39.6 1.5 RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 108.0;dendritic cells: 221.7;Hofbauer cells: 207.9;Kupffer cells: 551.2;Langerhans cells: 198.4;Macrophages: 270.3;monocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 65.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" 25.2 29.5 8.0 59.6 7.5 27.5 24.0 7.8 13.6 31.6 10.0 27.7 17.3 10.6 78.4 16.0 11.3 47.7 11.7 7.3 10.9 12.2 21.1 29.6 110.5 13.6 10.1 9.9 8.4 9.0 4.3 44.8 11.9 7.9 34.0 1.8 11.2 17.2 2.0 8.6 33.4 23.6 10.8 62.1 14.9 4.5 12.6 43.8 5.5 6.0 84.5 43.3 5.1 19.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 2.1 2.1 0.0 0.0 0.0 0.0 0.0 1.7 4.7 0.6 0.2 0.0 0.0 1.9 4.6 0.0 0.0 0.0 0.2 0.0 65.6 1.1 0.7 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 441.1 537.3 12.8 5.3 124.8 12.0 324.7 13.6 5.6 513.3 410.3 6.4 1.0 199.0 36.7 2.0 1238.8 1.1 329.8 8.0 7.5 7.8 13.6 7.3 10.9 13.6 10.1 11.9 10.8 12.6 19.5 1.6 6.4 7.5 0.0 108.0 4.5 0.2 0.0 1.8 0.0 1.4 2.8 0.6 14.3 1.2 0.0 0.0 1.1 221.7 2.6 0.0 0.0 0.8 0.1 0.0 3.8 0.0 12.0 0.0 0.0 1.6 1.4 1.1 0.2 0.0 0.0 8.6 3.3 207.9 0.0 0.0 0.5 2.0 551.2 198.4 4.8 2.8 270.3 21.4 1.9 115.8 0.0 9.2 0.0 0.0 0.0 12.6 0.7 52.4 0.2 0.4 0.5 0.2 0.4 13.1 0.6 0.6 0.1 0.7 0.6 3.8 2.2 7.8 0.0 3.4 1.2 ROGDI FLJ22386 ENSG00000067836 "Rogdi atypical leucine zipper" Q9GZN7 16 4796968-4802880 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amelogenesis imperfecta, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 105.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 179.2;Rod photoreceptor cells: 149.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 74.6;intermediate monocyte: 62.7;myeloid DC: 61.5;non-classical monocyte: 61.8;plasmacytoid DC: 34.5" "Group enriched" "Detected in all" 6 "dendritic cells: 61.5;monocytes: 74.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041000 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 56: Bipolar cells - Visual perception" "HPA041000: AB_10794077" "unprognostic (1.74e-3)" "unprognostic (1.98e-3)" "unprognostic (1.25e-1)" "unprognostic (1.01e-2)" "unprognostic (1.68e-1)" "unprognostic (1.95e-1)" "unprognostic (3.13e-1)" "unprognostic (3.79e-3)" "unprognostic (3.22e-2)" "unprognostic (1.21e-1)" "prognostic favorable (9.71e-4)" "unprognostic (5.24e-2)" "prognostic favorable (2.67e-5)" "unprognostic (1.71e-1)" "unprognostic (7.16e-2)" "unprognostic (2.17e-1)" "unprognostic (3.08e-2)" 7.5 24.1 82.9 11.6 84.5 78.0 7.3 81.3 105.6 8.8 64.3 17.6 24.8 7.5 6.6 18.1 14.5 14.4 44.2 91.4 83.9 19.3 19.7 15.5 8.6 84.0 84.9 5.9 22.9 26.4 18.2 7.9 80.9 19.0 7.6 61.9 25.3 16.6 63.1 6.5 21.4 11.3 79.4 15.6 21.1 8.2 96.8 10.1 4.6 32.9 8.7 11.2 6.4 97.6 13.5 18.8 9.5 42.4 12.2 6.2 36.4 9.4 4.6 8.2 3.6 12.5 15.3 5.9 15.1 19.9 5.3 26.7 9.9 28.7 3.2 4.8 13.3 8.0 28.9 28.1 19.8 10.4 6.5 8.3 11.7 12.4 8.3 21.6 14.5 11.5 5.7 3.5 14.1 74.9 9.4 51.0 15.3 15.4 14.2 30.1 26.1 30.1 19.8 18.1 55.3 24.5 38.6 42.4 9.9 11.9 50.9 40.8 22.3 7.3 17.0 52.5 6.5 14.2 17.0 5.2 8.6 40.0 6.5 10.5 74.6 8.1 2.1 62.7 6.6 2.5 5.4 4.9 61.5 2.8 4.7 5.5 6.7 6.7 61.8 34.5 6.1 38.0 82.9 84.5 81.3 105.6 91.4 83.9 84.0 84.9 80.9 79.4 96.8 97.6 7.0 19.2 7.8 17.3 6.7 5.1 28.0 84.4 32.5 179.2 23.0 22.5 58.1 21.5 36.7 27.6 110.5 46.9 11.5 23.4 39.2 22.2 30.3 17.6 8.5 12.0 52.0 38.7 33.2 16.0 73.4 15.9 11.7 7.2 5.7 9.8 24.3 19.7 64.8 25.2 19.2 29.7 69.2 28.7 29.0 57.0 6.8 31.0 12.4 10.3 77.0 102.5 6.2 7.5 90.2 13.5 23.7 19.2 4.6 12.7 65.7 80.8 21.3 149.7 6.6 8.2 15.3 6.5 20.7 24.8 5.8 30.6 9.5 64.7 23.1 22.3 RPH3A "exophilin-1, KIAA0985, rabphilin" ENSG00000089169 "Rabphilin 3A" Q9Y2J0 12 112570380-112898881 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 85.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 24.5;Excitatory neurons: 71.6;Inhibitory neurons: 100.6" "Cancer enriched" "Detected in some" 5 "glioma: 4.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 6.3" "Group enriched" "Detected in many" 5 "granulocytes: 2.3;monocytes: 6.3" "Cell line enhanced" "Detected in many" "RPMI-8226: 7.4;SH-SY5Y: 16.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002475 Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA002475: AB_1079837" "unprognostic (5.50e-2)" "unprognostic (3.19e-1)" "unprognostic (3.72e-3)" "unprognostic (5.90e-2)" "unprognostic (7.72e-3)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (1.96e-1)" "unprognostic (6.39e-2)" "unprognostic (6.75e-2)" "unprognostic (3.73e-2)" "unprognostic (1.42e-1)" "unprognostic (5.85e-2)" "unprognostic (3.92e-2)" "unprognostic (2.08e-2)" "unprognostic (2.70e-2)" "unprognostic (7.46e-2)" 0.5 3.6 15.0 1.5 23.9 20.7 0.8 23.8 85.5 0.3 0.0 0.8 1.0 1.3 2.4 0.9 0.6 1.9 0.6 16.8 14.4 0.6 0.8 0.5 3.4 27.2 24.0 0.8 2.4 0.2 0.4 1.3 7.7 0.7 1.2 9.7 0.9 0.4 0.6 2.1 1.1 1.3 17.3 1.8 0.6 1.4 50.1 0.6 1.1 0.4 1.9 0.8 0.2 46.0 0.7 0.3 0.7 1.2 0.3 0.5 2.0 0.0 0.4 0.5 0.1 0.6 1.0 1.1 0.3 0.0 0.6 2.0 0.3 0.5 0.9 0.4 1.4 1.9 3.2 2.1 0.4 1.1 1.8 0.6 0.2 1.3 1.0 0.7 0.0 0.3 0.1 2.7 1.8 0.7 0.6 1.5 1.1 0.2 1.1 0.0 0.9 7.4 0.0 1.5 0.9 16.5 0.2 0.1 0.1 1.6 0.7 0.1 0.1 1.6 1.2 1.5 0.9 1.2 0.3 1.1 1.0 0.8 0.4 1.2 6.3 0.2 0.2 3.0 0.1 0.3 0.1 0.2 0.6 0.8 0.2 0.3 2.3 0.5 4.6 0.2 0.0 1.8 15.0 23.9 23.8 85.5 16.8 14.4 27.2 24.0 7.7 17.3 50.1 46.0 0.0 0.0 0.0 5.5 0.2 0.0 0.0 0.0 0.0 24.5 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.2 0.0 0.0 71.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 100.6 0.0 0.0 1.2 0.0 7.2 0.0 3.2 0.0 2.8 5.8 1.2 0.0 12.5 3.8 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RPL26L1 RPL26P1 ENSG00000037241 "Ribosomal protein L26 like 1" Q9UNX3 5 172958729-172969771 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 408.0;Spermatocytes: 316.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030449 Approved Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA030449: AB_10602125" "unprognostic (3.02e-1)" "unprognostic (1.41e-1)" "unprognostic (3.39e-2)" "unprognostic (4.12e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (2.04e-3)" "unprognostic (2.45e-1)" "unprognostic (7.51e-2)" "unprognostic (5.86e-3)" "unprognostic (3.18e-1)" "unprognostic (1.06e-1)" "unprognostic (7.17e-2)" "unprognostic (2.55e-1)" "unprognostic (1.90e-1)" "unprognostic (1.14e-1)" "unprognostic (2.14e-3)" 27.4 45.8 28.0 28.9 29.2 39.1 27.3 29.7 39.1 23.5 26.4 24.5 25.2 28.5 37.7 37.5 26.6 22.1 37.8 31.0 29.8 43.7 47.9 22.1 34.4 29.3 28.9 25.7 24.9 34.5 30.3 23.8 30.6 25.5 26.2 17.9 24.6 28.9 37.8 21.3 21.9 26.0 28.1 26.8 26.2 91.2 29.3 34.0 29.5 28.1 29.0 30.4 25.4 29.1 129.8 114.7 101.9 140.8 68.9 72.3 131.7 120.6 70.6 170.5 151.1 141.1 135.3 96.6 301.5 166.6 181.6 82.1 170.1 239.8 156.4 124.1 220.9 71.6 122.8 174.5 135.1 105.7 60.8 91.0 99.2 176.1 122.3 69.1 99.2 93.6 100.3 79.0 123.1 286.6 129.5 165.6 65.2 59.7 180.5 93.3 157.5 128.4 101.0 80.1 102.0 62.7 110.6 100.2 167.6 64.7 122.8 111.5 105.4 193.2 109.0 114.3 92.5 70.3 119.0 182.3 152.6 130.2 117.6 25.4 86.6 39.9 33.1 80.5 42.7 50.4 40.4 46.1 99.5 38.1 32.9 42.0 42.9 39.5 72.2 68.1 55.8 55.7 28.0 29.2 29.7 39.1 31.0 29.8 29.3 28.9 30.6 28.1 29.3 29.1 41.5 41.7 32.8 4.6 29.8 48.8 56.9 191.3 32.5 18.8 50.2 61.8 45.5 41.5 82.7 58.8 18.8 111.6 28.7 36.2 181.9 119.0 408.0 98.4 70.0 47.7 40.2 49.2 4.5 113.0 124.5 45.3 29.6 70.6 26.6 60.2 41.4 132.1 115.0 15.2 5.2 48.6 93.6 48.6 51.9 79.9 37.9 45.6 51.6 2.8 93.5 61.7 49.4 2.0 5.0 138.0 38.6 41.0 59.2 67.9 48.2 216.2 92.4 20.2 19.7 35.6 56.1 316.7 178.6 70.5 52.8 78.9 28.9 81.1 59.1 57.7 RTN1 NSP ENSG00000139970 "Reticulon 1" Q16799 14 59595976-59870776 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 160.6;pituitary gland: 60.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 495.8;Horizontal cells: 240.6;Inhibitory neurons: 394.3;Oligodendrocyte precursor cells: 188.0;Oligodendrocytes: 247.7" "Cancer enhanced" "Detected in many" "glioma: 19.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.9;intermediate monocyte: 3.1;myeloid DC: 5.4" "Group enriched" "Detected in many" 14 "dendritic cells: 5.4;monocytes: 3.1" "Group enriched" "Detected in some" 4 "HEL: 61.7;SCLC-21H: 71.8;SH-SY5Y: 115.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002745, HPA040945, HPA044249" Enhanced Supported "Nuclear bodies,Endoplasmic reticulum" NA NA 150000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" "Nuclear bodies" "CAB002745: , HPA040945: AB_2677217, HPA044249: AB_2678874" "unprognostic (9.40e-3)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (2.61e-1)" "unprognostic (4.24e-2)" "unprognostic (3.04e-3)" "unprognostic (8.67e-2)" "unprognostic (1.23e-2)" "unprognostic (2.49e-1)" "unprognostic (2.79e-1)" "prognostic favorable (3.69e-4)" "unprognostic (5.79e-2)" "unprognostic (2.23e-1)" "unprognostic (4.00e-2)" "unprognostic (1.75e-1)" "unprognostic (6.71e-2)" "unprognostic (1.62e-2)" 11.1 12.0 111.1 9.3 127.5 0.4 7.2 57.0 134.7 2.2 0.0 7.6 2.5 1.3 0.4 1.6 12.8 5.5 0.9 133.0 160.6 1.6 1.0 6.4 2.7 37.5 24.9 0.7 4.0 17.4 60.1 2.4 46.7 6.4 2.8 34.1 3.4 1.9 0.8 3.2 4.1 2.4 10.8 18.3 3.9 2.3 68.3 1.0 2.5 0.7 1.8 1.9 3.6 50.2 0.0 0.0 0.7 1.0 2.9 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.9 0.1 0.4 0.0 2.1 61.7 0.0 0.0 3.4 0.1 0.2 0.0 0.1 0.0 2.1 0.0 0.5 0.4 0.0 0.3 0.7 0.3 0.0 0.0 4.9 0.0 0.0 0.0 0.6 0.1 0.0 0.0 71.8 115.1 14.9 0.0 0.0 0.2 0.0 0.0 0.0 9.9 2.8 0.1 5.6 0.0 0.0 0.0 19.4 4.4 0.7 0.0 2.9 0.0 0.0 3.1 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.7 111.1 127.5 57.0 134.7 133.0 160.6 37.5 24.9 46.7 10.8 68.3 50.2 1.0 0.0 1.1 64.3 0.5 4.8 0.4 0.0 0.0 34.1 11.4 4.3 1.0 1.5 0.6 0.0 25.0 1.2 1.4 0.8 0.0 0.0 16.2 23.5 0.3 2.9 54.2 0.8 495.8 0.0 5.0 1.5 5.6 0.4 0.0 0.2 0.0 0.5 17.8 240.6 394.3 3.6 0.0 14.4 59.7 21.4 2.8 23.8 10.6 87.1 22.8 14.3 0.0 188.0 247.7 1.4 0.1 1.2 0.1 5.8 0.8 0.9 0.7 33.3 0.0 10.7 2.5 2.3 3.8 0.2 6.5 2.5 0.7 0.1 0.5 0.3 RXFP2 "GPR106, GREAT, INSL3R, LGR8, RXFPR2" ENSG00000133105 "Relaxin family peptide receptor 2" Q8WXD0 13 31739526-31803389 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 7 "Early spermatids: 8.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "classical monocyte: 1.7" "Lineage enriched" "Detected in single" 18 "monocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "basal ganglia: 2.6" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (1.77e-2)" 0.1 0.5 0.0 0.0 0.7 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.2 0.3 0.2 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 S1PR3 "EDG-3, EDG3" ENSG00000213694 "Sphingosine-1-phosphate receptor 3" "Q99500, Q6ZRZ4" 9 88990863-89005155 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 55.5;Sertoli cells: 65.7;Smooth muscle cells: 35.0;Theca cells: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "classical monocyte: 7.0" "Lineage enriched" "Detected in single" 18 "monocytes: 7.0" "Cell line enhanced" "Detected in many" "AF22: 116.0;ASC diff: 157.9;ASC TERT1: 158.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "prognostic favorable (5.91e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.91e-3)" "unprognostic (2.02e-1)" "unprognostic (4.41e-2)" "unprognostic (2.77e-2)" "unprognostic (5.22e-2)" "unprognostic (1.94e-2)" "unprognostic (3.15e-1)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.91e-6)" "unprognostic (4.43e-2)" "unprognostic (1.48e-2)" "unprognostic (3.93e-2)" "unprognostic (1.37e-1)" 18.3 25.0 5.8 10.6 6.4 3.2 11.2 6.9 6.7 32.2 10.7 14.8 4.5 17.2 6.2 17.6 26.0 14.2 17.5 6.3 11.2 36.9 6.1 8.9 11.4 16.1 9.8 5.1 11.7 1.7 17.0 15.1 7.7 20.1 3.4 4.2 3.9 11.9 4.4 3.1 10.7 36.0 8.4 13.2 12.5 2.2 12.4 4.7 4.8 8.2 9.4 20.4 20.9 13.2 0.5 17.7 116.0 6.0 157.9 158.7 0.1 24.8 61.4 17.0 17.0 0.2 0.0 0.0 0.3 37.2 16.6 0.2 0.3 18.0 11.5 0.0 1.2 0.0 23.3 0.1 13.7 8.1 0.1 28.6 1.0 22.2 4.0 13.2 29.9 17.0 2.1 0.1 4.7 17.1 14.3 8.7 11.2 0.8 6.2 1.5 0.0 0.1 0.3 7.1 1.5 8.1 23.4 5.7 0.0 22.8 2.7 7.4 60.3 25.4 10.3 27.8 4.1 0.0 0.1 0.0 36.8 7.1 9.1 0.3 7.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 2.1 5.8 6.4 6.9 6.7 6.3 11.2 16.1 9.8 7.7 8.4 12.4 13.2 3.0 0.0 1.7 3.6 0.0 10.1 9.5 1.8 2.8 1.0 9.9 3.7 9.2 1.5 1.7 1.8 2.1 17.9 0.1 0.0 0.0 0.3 0.0 2.1 55.5 10.6 0.0 0.0 0.5 0.5 1.3 21.5 0.5 2.4 0.0 3.8 1.8 1.6 2.4 3.3 1.7 0.0 0.0 1.8 4.0 0.5 3.7 4.4 0.0 7.5 6.9 7.1 0.0 0.0 0.2 0.9 0.0 6.8 0.2 7.0 0.0 1.4 2.9 1.6 65.7 16.1 35.0 0.0 1.2 1.5 3.3 5.5 2.2 65.8 0.0 6.4 SAP30 ENSG00000164105 "Sin3A associated protein 30" O75446 4 173369969-173377532 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 77.2;Macrophages: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022627, HPA059012" Enhanced Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB022627: , HPA059012: AB_2683880" "unprognostic (1.53e-1)" "unprognostic (3.67e-2)" "unprognostic (3.26e-1)" "unprognostic (1.39e-1)" "unprognostic (5.83e-2)" "unprognostic (8.71e-2)" "prognostic unfavorable (1.24e-6)" "unprognostic (4.95e-2)" "unprognostic (7.23e-2)" "unprognostic (3.93e-2)" "unprognostic (4.48e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (3.97e-1)" "unprognostic (5.70e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" 17.4 12.9 17.4 13.3 19.7 23.4 12.8 18.4 21.6 13.9 16.1 25.6 9.5 13.2 9.6 9.9 16.9 8.6 20.4 17.0 18.2 6.2 9.0 12.8 8.0 19.3 18.2 14.6 7.3 4.5 8.1 7.1 19.2 11.4 7.0 16.3 11.6 9.7 10.5 8.5 12.5 12.4 18.7 15.7 18.4 24.7 17.6 10.3 10.6 7.4 6.6 19.5 12.6 25.3 49.0 16.3 46.3 45.2 29.0 17.9 10.1 22.5 19.3 24.7 30.4 7.0 19.4 43.9 10.3 26.3 31.1 12.0 37.8 19.1 18.9 49.6 35.9 58.7 39.6 20.0 27.5 34.0 35.9 29.8 9.2 21.1 21.2 34.7 29.3 31.5 30.8 181.4 32.2 20.9 48.4 38.0 20.5 21.7 31.3 38.9 16.5 31.6 15.1 7.8 37.5 79.1 31.8 31.9 14.9 11.8 13.5 20.0 29.1 17.6 23.9 41.4 52.8 101.5 39.1 41.8 56.8 81.6 51.2 0.4 1.3 0.0 0.6 0.7 0.2 0.1 0.3 0.4 1.0 0.2 0.0 0.2 0.5 0.0 0.4 0.0 0.4 0.2 17.4 19.7 18.4 21.6 17.0 18.2 19.3 18.2 19.2 18.7 17.6 25.3 42.1 0.0 2.3 11.1 7.2 51.7 6.6 3.9 16.5 26.2 25.5 29.3 28.9 4.3 3.7 7.3 22.9 2.1 22.5 4.8 0.0 2.2 23.1 23.6 34.3 27.3 19.7 20.2 12.5 3.5 9.3 19.9 19.4 7.4 7.0 13.5 14.6 9.0 9.3 25.2 14.6 10.5 0.0 77.2 13.8 6.2 10.2 77.0 33.8 3.7 15.2 57.7 2.1 7.1 15.4 2.4 2.7 6.4 17.6 8.6 6.4 6.2 9.9 46.3 52.6 12.5 31.7 63.7 15.2 16.1 53.0 1.2 27.0 12.3 11.1 4.1 SAT2 SSAT2 ENSG00000141504 "Spermidine/spermine N1-acetyltransferase family member 2" Q96F10 17 7626234-7627876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 139.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 1060.0;Proximal tubular cells: 1313.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022136, HPA057096" Enhanced NA NA 11000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA022136: AB_1856592, HPA057096: AB_2683334" "unprognostic (2.61e-2)" "unprognostic (1.27e-2)" "unprognostic (3.23e-2)" "prognostic favorable (8.76e-6)" "unprognostic (2.18e-2)" "unprognostic (2.32e-1)" "unprognostic (7.20e-2)" "prognostic favorable (6.71e-4)" "unprognostic (4.14e-2)" "unprognostic (2.75e-1)" "prognostic favorable (6.05e-5)" "unprognostic (1.83e-1)" "unprognostic (6.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.86e-1)" "unprognostic (1.50e-1)" "unprognostic (3.12e-2)" 28.3 102.8 27.7 9.6 28.4 11.3 26.8 28.7 37.5 26.2 32.9 30.5 92.7 25.2 25.1 17.2 26.1 15.8 33.5 27.9 29.2 97.6 139.8 19.0 9.5 28.4 28.5 44.5 47.4 36.0 30.4 8.6 28.3 27.4 15.4 21.1 27.0 16.4 31.8 19.0 65.5 17.1 28.9 29.1 33.4 17.1 29.2 8.0 28.2 20.5 11.8 22.6 19.8 28.8 17.9 27.3 24.1 44.9 37.5 43.6 3.0 12.2 44.3 27.2 33.8 9.3 8.9 3.3 6.8 11.9 30.4 15.3 15.4 11.1 18.0 5.1 41.9 3.6 15.8 49.2 45.3 0.1 12.3 54.6 28.3 16.2 11.9 36.6 39.9 3.5 2.5 5.3 28.8 1.6 0.3 4.1 9.9 10.2 16.6 6.6 11.8 4.2 42.8 20.6 2.6 22.4 11.4 23.4 26.3 21.4 15.5 3.3 17.3 13.2 8.5 0.3 19.3 9.9 9.6 0.7 44.5 5.2 19.7 7.6 41.9 9.5 14.2 28.3 16.7 13.6 12.0 14.6 30.7 12.7 17.8 12.7 2.7 12.4 14.9 14.0 19.5 22.5 27.7 28.4 28.7 37.5 27.9 29.2 28.4 28.5 28.3 28.9 29.2 28.8 70.3 44.8 121.2 76.4 76.2 82.6 90.6 83.2 134.3 121.9 124.1 140.8 62.8 257.4 82.6 80.9 68.8 70.8 68.7 80.4 422.6 135.9 19.4 66.9 79.0 69.8 132.7 25.9 86.2 66.2 33.7 97.3 43.3 59.2 62.1 181.4 114.5 289.0 165.3 129.5 64.6 116.4 124.1 142.7 165.1 28.0 181.7 110.7 94.3 25.3 103.4 156.9 49.4 32.6 36.9 92.8 129.1 119.2 92.9 108.6 1060.0 1313.7 83.9 148.6 72.3 91.2 92.2 30.4 7.8 79.6 56.1 79.2 67.0 321.2 116.8 103.9 SERPINB1 "anti-elastase, EI, ELANH2, PI2" ENSG00000021355 "Serpin family B member 1" P30740 6 2832332-2841959 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 466.8;esophagus: 478.3" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 1424.3;Pancreatic endocrine cells: 1067.8;Urothelial cells: 984.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.3;OE19: 162.5;U-937: 144.9" "Low region specificity" "Detected in all" "HPA018871, HPA018882, HPA052642" Enhanced Supported "Cytoplasmic bodies" "Secreted to blood" NA NA 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cytoplasmic bodies" "HPA018871: AB_1856724, HPA018882: , HPA052642: AB_2681896" "unprognostic (1.13e-2)" "unprognostic (1.93e-1)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (5.14e-3)" "unprognostic (9.67e-2)" "unprognostic (3.59e-3)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (1.88e-2)" "unprognostic (1.08e-3)" "unprognostic (9.07e-2)" "unprognostic (1.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" 36.6 54.4 10.7 69.7 14.4 466.8 25.0 11.1 14.0 55.6 17.3 77.7 140.4 15.6 22.2 478.3 35.8 57.4 26.8 10.7 12.7 33.2 32.1 81.7 51.3 15.1 13.0 18.1 232.1 29.8 32.9 27.0 14.6 15.9 87.5 13.4 99.6 16.9 54.2 15.8 107.3 24.9 13.6 67.4 97.9 7.1 13.7 31.9 30.7 22.9 122.8 88.6 112.4 14.8 42.9 49.7 2.7 0.3 10.6 21.8 41.2 11.8 36.1 14.5 26.1 47.1 125.3 0.3 86.6 26.6 15.6 26.8 4.8 11.4 11.1 59.4 7.5 76.6 16.0 37.0 37.2 13.5 46.2 26.8 18.4 7.3 3.3 7.2 48.7 0.0 27.1 9.9 13.4 19.9 1.7 35.4 4.5 162.5 22.1 3.9 0.5 44.4 51.0 9.3 8.8 4.8 28.8 11.2 64.2 5.9 5.6 43.2 29.1 4.6 10.4 10.2 3.6 0.1 2.2 0.5 17.4 144.9 2.4 118.0 207.1 109.4 53.3 103.7 45.8 43.5 48.1 48.4 150.4 32.3 47.4 50.6 182.3 85.1 82.8 48.6 58.5 175.8 10.7 14.4 11.1 14.0 10.7 12.7 15.1 13.0 14.6 13.6 13.7 14.8 79.9 240.4 269.9 0.7 90.7 35.1 165.1 699.1 38.1 4.2 55.0 51.2 17.6 72.9 420.9 46.0 2.1 124.5 120.8 264.1 56.7 490.3 1.7 210.6 28.7 118.9 96.3 176.3 0.9 1424.3 149.1 89.1 345.1 104.5 452.2 32.1 124.9 20.2 183.0 10.1 0.9 263.1 109.9 332.7 308.2 3.5 34.8 387.3 71.2 15.9 589.7 48.3 139.0 4.5 6.6 1067.8 308.4 27.8 65.2 147.5 333.7 81.3 343.8 17.2 13.1 109.7 67.2 2.0 11.2 461.5 38.1 99.7 112.9 59.2 242.6 984.3 SGMS2 "MGC26963, SMS2" ENSG00000164023 "Sphingomyelin synthase 2" Q8NHU3 4 107824563-107915047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 126.6;Basal prostatic cells: 167.4;Endometrial ciliated cells: 172.1;Glandular and luminal cells: 147.8;Urothelial cells: 159.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 3.7;eosinophil: 2.4;intermediate monocyte: 1.5;myeloid DC: 4.2;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 35 "dendritic cells: 4.2;granulocytes: 2.4;monocytes: 3.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015076 Supported NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA015076: AB_1857298" "unprognostic (7.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.36e-2)" "unprognostic (1.87e-2)" "unprognostic (7.88e-3)" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (1.32e-1)" "unprognostic (4.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.82e-3)" "unprognostic (3.26e-1)" "prognostic favorable (1.37e-4)" "unprognostic (6.18e-2)" "unprognostic (5.63e-2)" "unprognostic (8.71e-2)" "unprognostic (5.22e-3)" 8.6 3.0 5.2 9.0 15.3 4.6 5.2 10.1 7.8 12.7 36.7 12.3 19.5 8.8 4.6 16.4 12.5 39.6 9.1 3.3 6.5 14.5 20.4 27.8 1.1 13.9 14.3 1.1 11.7 3.6 4.7 5.1 13.0 9.6 10.6 0.8 9.2 4.6 2.5 3.6 16.5 29.1 10.2 1.1 13.8 9.6 10.6 0.8 18.0 3.4 2.9 13.9 4.2 21.6 20.8 7.7 1.1 5.8 12.9 29.9 0.4 25.0 18.8 11.6 12.1 3.5 42.1 1.5 9.7 40.0 10.1 7.6 14.5 22.1 20.7 5.9 5.7 0.9 16.5 1.2 14.8 14.2 0.1 10.4 15.1 22.7 27.4 24.2 26.1 0.3 0.2 0.5 18.6 6.9 0.5 0.1 0.7 12.1 8.6 0.5 9.9 2.9 30.7 10.0 2.0 0.1 19.1 26.9 3.3 3.0 14.5 0.4 44.7 13.9 21.9 20.1 11.7 1.4 0.5 0.8 18.7 3.4 5.9 0.0 3.7 2.4 0.0 1.5 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.3 0.0 1.4 0.0 0.0 1.0 5.2 15.3 10.1 7.8 3.3 6.5 13.9 14.3 13.0 10.2 10.6 21.6 3.4 86.6 126.6 7.2 1.0 56.0 167.4 12.8 18.2 0.5 20.9 10.4 17.8 28.6 88.0 16.5 0.0 1.0 2.9 32.3 3.9 19.8 71.4 172.1 13.5 10.7 8.9 0.0 8.0 19.5 0.9 26.6 58.1 147.8 10.1 2.8 11.4 25.0 5.5 1.7 10.0 26.0 14.2 22.1 43.0 11.1 2.5 28.2 8.8 1.9 23.3 0.2 2.1 0.5 18.5 37.9 60.5 0.4 0.4 96.9 33.5 12.4 104.0 0.1 0.0 46.1 22.0 0.9 3.1 38.1 72.9 13.8 3.3 0.1 21.8 159.7 SHROOM1 "APXL2, KIAA1960" ENSG00000164403 "Shroom family member 1" Q2M3G4 5 132822141-132830659 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 116.9;prostate: 73.9;urinary bladder: 62.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.0;Hepatocytes: 79.2;Proximal enterocytes: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 24.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037690, HPA037691" Uncertain Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA037690: AB_2675613, HPA037691: AB_2675614" "unprognostic (2.50e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (2.66e-1)" "unprognostic (1.45e-2)" "unprognostic (3.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.33e-2)" "unprognostic (3.74e-1)" "unprognostic (3.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.22e-2)" "unprognostic (2.91e-2)" "unprognostic (2.88e-2)" "unprognostic (2.26e-3)" 9.3 2.4 25.2 2.6 32.0 0.2 8.2 28.9 26.9 12.6 10.4 20.5 6.1 11.3 2.1 5.1 8.4 6.7 7.6 20.2 23.6 10.7 116.9 10.5 0.6 42.1 30.9 5.6 16.2 4.9 6.8 11.8 33.3 73.9 11.1 3.4 7.0 15.2 1.7 1.5 16.6 3.9 26.1 2.3 10.9 1.7 31.2 0.6 6.9 1.3 0.5 62.4 9.3 55.7 8.6 5.1 0.9 0.8 1.4 4.0 9.0 9.1 7.7 7.0 7.8 11.2 5.7 1.5 12.5 4.9 3.8 0.8 3.1 5.7 4.3 9.5 11.0 0.3 8.7 10.5 4.1 0.7 3.1 1.7 3.0 4.9 3.0 4.8 4.8 0.1 7.3 8.1 6.1 4.8 0.2 4.0 1.4 6.7 8.1 0.5 0.0 0.8 1.2 24.4 5.7 1.5 8.8 0.7 4.9 4.5 5.2 2.9 4.5 8.1 11.7 1.1 11.5 9.2 6.8 0.1 7.9 0.0 2.5 0.2 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 25.2 32.0 28.9 26.9 20.2 23.6 42.1 30.9 33.3 26.1 31.2 55.7 18.3 25.6 22.3 18.9 1.8 1.3 15.4 2.3 3.4 3.7 9.3 5.5 2.2 30.0 11.3 9.2 10.4 6.8 1.0 135.0 1.9 6.0 0.9 7.1 17.3 18.1 22.8 2.7 3.0 10.7 4.8 6.1 33.6 15.1 8.2 9.0 25.0 79.2 6.6 16.8 1.0 28.6 0.0 8.7 5.5 1.1 4.7 4.6 0.0 23.4 8.1 19.9 3.1 6.6 37.5 7.1 53.6 4.9 3.6 31.6 65.5 3.5 9.1 13.3 26.3 2.8 5.1 7.6 5.1 1.8 2.0 2.9 2.5 1.4 35.5 17.3 SHTN1 "KIAA1598, shootin-1, shootin1" ENSG00000187164 "Shootin 1" A0MZ66 10 116881477-117126586 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 128.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "classical monocyte: 19.7;intermediate monocyte: 12.9;myeloid DC: 19.3;non-classical monocyte: 6.6;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 42 "dendritic cells: 19.3;monocytes: 19.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037942, HPA037943" Enhanced Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA037942: AB_2675748, HPA037943: AB_10671637" "unprognostic (1.00e-1)" "unprognostic (2.50e-2)" "unprognostic (6.77e-3)" "unprognostic (2.81e-1)" "unprognostic (7.85e-2)" "unprognostic (1.61e-1)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.56e-1)" "unprognostic (1.35e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (2.17e-2)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.08e-6)" 1.9 4.0 63.2 4.5 94.5 0.7 4.9 42.7 54.1 2.9 10.0 4.3 4.1 2.4 4.6 3.1 2.9 3.8 1.6 46.9 73.9 4.7 7.6 6.2 2.9 77.5 70.1 3.9 12.2 8.0 6.2 3.1 69.5 4.2 5.2 10.6 6.7 1.4 0.3 5.6 4.8 2.0 48.6 4.5 5.7 6.4 79.5 2.7 7.5 0.8 2.3 2.1 2.1 128.1 24.2 13.4 1.3 2.8 0.0 0.0 12.8 2.0 5.3 4.0 7.6 15.1 15.5 0.0 4.0 7.4 11.8 12.2 10.6 8.9 4.1 0.0 11.0 0.0 14.5 8.9 1.7 4.3 3.7 0.5 7.5 4.0 7.5 10.3 9.7 6.4 6.7 0.1 2.8 9.6 0.0 0.1 5.0 4.8 8.9 0.0 17.5 5.4 10.3 3.3 14.5 5.7 16.0 23.3 13.8 15.7 18.4 3.8 17.0 1.4 9.4 0.1 11.7 2.4 0.1 0.0 7.1 0.0 7.2 0.0 19.7 0.2 0.0 12.9 0.0 0.0 0.1 0.0 19.3 0.0 0.1 0.0 0.4 0.0 6.6 12.9 0.4 5.6 63.2 94.5 42.7 54.1 46.9 73.9 77.5 70.1 69.5 48.6 79.5 128.1 1.4 76.9 35.7 0.0 2.0 0.0 18.9 0.0 15.4 92.3 31.8 15.9 4.9 35.8 23.5 23.9 62.6 42.1 24.7 10.6 21.5 46.4 7.5 43.4 10.6 5.1 17.0 1.7 0.0 53.2 30.9 11.2 36.7 81.1 2.5 23.6 1.8 50.5 37.3 48.8 0.0 15.5 0.0 83.6 0.0 11.7 11.1 77.2 0.0 0.0 90.3 13.8 1.0 0.0 0.0 46.2 42.5 5.3 0.8 25.2 21.2 58.4 18.2 59.4 13.1 18.2 5.0 22.0 39.6 20.5 0.0 20.0 3.1 28.4 15.7 15.4 SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 11 "Hofbauer cells: 78.6;Kupffer cells: 93.4;Macrophages: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Cell line enriched" "Detected in single" 19 "THP-1: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" NA NA 260000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" 23.0 13.7 2.0 7.7 2.9 12.3 8.6 1.9 6.5 1.8 7.5 10.2 5.1 2.0 1.8 2.2 7.0 8.5 6.4 1.8 2.2 3.9 8.4 16.7 12.7 10.2 3.3 2.7 1.6 0.5 2.3 18.8 10.9 1.9 6.6 0.3 5.4 1.2 3.7 3.0 11.2 7.7 5.0 18.9 5.1 2.5 10.9 3.6 3.7 2.6 1.9 7.6 3.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 2.0 2.9 1.9 6.5 1.8 2.2 10.2 3.3 10.9 5.0 10.9 3.9 0.5 3.2 4.4 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.0 0.3 2.4 0.0 0.6 0.0 2.1 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.2 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.3 0.0 0.0 93.4 6.3 0.1 0.0 42.6 0.0 3.7 2.1 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 1.4 1.0 0.0 0.1 0.6 0.6 1.9 0.4 0.0 0.0 0.0 SIGLEC15 "CD33L3, HsT1361" ENSG00000197046 "Sialic acid binding Ig like lectin 15" Q6ZMC9 18 45825675-45844094 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 1.7;intestine: 3.0;urinary bladder: 1.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 3.6;Hofbauer cells: 10.1;Macrophages: 3.7;Pancreatic endocrine cells: 3.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "classical monocyte: 3.0;myeloid DC: 1.0" "Group enriched" "Detected in many" 21 "dendritic cells: 1.0;monocytes: 3.0" "Cell line enriched" "Detected in some" 5 "U-87 MG: 124.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053509 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA053509: " "unprognostic (3.89e-3)" "unprognostic (1.87e-2)" "unprognostic (1.77e-1)" "unprognostic (7.18e-3)" "unprognostic (2.27e-1)" "unprognostic (8.07e-2)" "unprognostic (5.91e-2)" "unprognostic (2.71e-1)" "unprognostic (9.63e-2)" "unprognostic (1.06e-1)" "unprognostic (1.77e-2)" "unprognostic (7.65e-2)" "unprognostic (6.55e-2)" "unprognostic (1.42e-1)" "unprognostic (6.06e-2)" "unprognostic (4.40e-2)" "prognostic favorable (9.14e-5)" 0.0 0.4 0.1 0.3 0.4 0.0 1.7 0.6 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 3.0 0.0 0.0 1.0 1.3 0.0 0.0 0.2 0.0 0.0 0.6 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.9 0.3 1.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.1 0.0 2.3 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.4 10.9 2.1 0.3 0.0 22.7 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 5.5 0.0 0.1 1.3 0.0 0.0 0.0 124.2 2.9 0.2 0.0 3.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.4 0.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.9 1.3 0.0 0.0 1.0 3.6 0.9 0.8 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.5 0.4 0.2 1.0 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.7 0.0 0.0 2.2 0.4 10.1 1.7 0.1 0.2 0.0 1.6 2.5 0.0 0.0 3.7 0.0 0.0 1.6 0.0 1.0 0.0 0.0 3.5 0.1 0.0 0.0 1.1 1.2 0.1 0.0 1.0 0.0 1.5 0.4 1.2 0.1 0.0 0.3 0.0 0.3 0.0 0.1 2.8 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SIL1 "BAP, MSS, ULG5" ENSG00000120725 "SIL1 nucleotide exchange factor" Q9H173 5 138946724-139293557 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011949 Enhanced "Intracellular and membrane" NA NA 710000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "HPA011949: AB_1856875" "unprognostic (1.06e-1)" "unprognostic (9.01e-2)" "unprognostic (2.04e-1)" "prognostic favorable (4.34e-4)" "prognostic unfavorable (4.27e-4)" "unprognostic (9.12e-3)" "unprognostic (3.60e-1)" "unprognostic (2.45e-1)" "unprognostic (1.33e-1)" "unprognostic (6.91e-2)" "unprognostic (2.31e-2)" "unprognostic (9.46e-2)" "unprognostic (3.21e-3)" "unprognostic (1.59e-1)" "unprognostic (1.65e-1)" "unprognostic (6.79e-2)" "unprognostic (1.22e-2)" 26.4 46.4 9.0 19.7 10.6 24.1 21.6 8.5 11.8 21.7 17.9 20.0 24.6 21.7 32.5 16.5 19.2 23.2 29.5 9.2 9.3 20.9 54.9 22.6 14.1 10.6 9.9 19.1 67.7 33.7 28.5 28.7 10.5 23.9 12.8 5.7 36.7 25.8 41.4 23.2 16.4 17.2 8.2 17.3 29.5 49.8 11.3 9.0 36.2 18.0 10.0 20.6 16.2 10.3 33.7 34.9 11.3 56.2 84.0 48.3 65.0 54.0 58.2 26.6 57.3 36.9 78.9 12.4 89.7 74.2 32.2 29.8 12.0 76.0 15.8 33.7 20.7 16.4 23.9 40.9 67.2 4.9 72.6 60.7 73.1 46.4 79.0 42.7 40.5 15.4 8.7 131.3 32.2 52.1 12.4 15.1 2.4 38.6 4.2 8.9 7.8 92.7 38.9 17.7 19.5 13.0 46.3 44.3 74.5 24.8 38.4 30.6 30.6 46.8 10.9 17.9 23.6 56.3 31.6 8.2 34.3 38.1 39.9 18.1 47.7 19.4 17.4 52.4 10.9 20.1 12.1 16.8 51.3 14.7 12.1 15.1 5.7 22.1 42.3 37.3 11.7 27.1 9.0 10.6 8.5 11.8 9.2 9.3 10.6 9.9 10.5 8.2 11.3 10.3 22.5 19.2 47.0 51.6 32.5 22.0 33.4 61.6 15.4 9.0 33.8 21.6 30.3 38.6 48.1 42.3 37.5 121.2 19.0 41.5 11.7 61.8 109.1 25.5 37.0 21.9 33.5 7.6 75.7 81.7 104.2 46.3 38.7 32.1 60.3 29.2 29.3 143.8 70.3 25.2 73.7 64.3 52.9 33.9 21.0 195.7 28.6 36.7 48.0 49.6 113.8 15.2 17.5 66.4 57.6 46.2 34.9 22.2 114.5 32.1 51.1 46.5 51.6 26.6 19.7 21.4 27.7 96.9 61.8 13.0 23.9 153.6 16.9 60.3 43.0 30.1 SLC11A1 "LSH, NRAMP, NRAMP1" ENSG00000018280 "Solute carrier family 11 member 1" P49279 2 218382029-218396894 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 78.6;lymphoid tissue: 46.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 108.0;Kupffer cells: 166.8;Macrophages: 209.4;monocytes: 101.2" "Cancer enhanced" "Detected in many" "glioma: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 6.1;intermediate monocyte: 4.5;myeloid DC: 1.9;neutrophil: 4.1;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 11 "dendritic cells: 1.9;granulocytes: 4.1;monocytes: 6.1" "Cell line enhanced" "Detected in some" "HEL: 1.2;HMC-1: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA029590, HPA050378, HPA068540" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria Nucleoli "HPA029590: AB_10794613, HPA050378: , HPA068540: " "unprognostic (2.64e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-2)" "unprognostic (2.34e-2)" "unprognostic (1.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.04e-3)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" "unprognostic (7.29e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.58e-8)" "unprognostic (9.55e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-2)" 14.1 8.5 3.5 7.1 4.3 6.7 4.9 3.9 11.1 2.7 4.7 3.5 0.2 2.2 0.1 1.6 7.4 1.0 8.0 3.3 5.0 3.4 5.1 78.6 0.2 7.4 5.2 1.7 3.2 0.3 3.1 2.7 6.9 3.2 0.0 0.6 3.2 0.1 1.7 1.5 2.2 1.9 5.2 46.6 3.0 0.9 17.3 0.3 2.7 1.3 0.0 7.2 2.4 7.4 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.2 0.2 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.0 0.4 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 6.1 0.6 0.3 4.5 0.2 0.1 0.2 0.1 1.9 0.2 0.3 0.2 4.1 0.2 6.0 0.2 0.2 2.0 3.5 4.3 3.9 11.1 3.3 5.0 7.4 5.2 6.9 5.2 17.3 7.4 1.5 22.4 38.5 1.6 4.1 0.9 4.3 1.9 1.2 3.1 4.5 4.6 8.6 2.8 13.8 9.2 0.0 1.8 3.1 1.8 9.8 1.3 1.8 6.1 2.3 17.0 1.2 1.7 1.3 2.1 7.8 5.8 2.0 2.8 25.3 0.9 6.8 7.3 108.0 1.7 0.9 4.0 6.1 166.8 6.3 0.5 2.1 209.4 1.8 4.7 101.2 12.9 10.3 0.5 1.4 0.4 1.6 0.7 5.6 3.9 2.5 11.7 11.0 3.3 19.7 2.9 4.2 0.8 1.8 2.1 1.0 8.1 6.7 3.3 2.9 3.3 SLC1A3 "EA6, EAAT1, GLAST" ENSG00000079215 "Solute carrier family 1 member 3" P43003 5 36596588-36688334 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 10 "brain: 776.8;choroid plexus: 400.6;retina: 221.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1735.2;Microglial cells: 332.6;Muller glia cells: 472.6;Oligodendrocyte precursor cells: 237.7;Oligodendrocytes: 249.0" "Cancer enriched" "Detected in all" 21 "glioma: 168.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 1.5;intermediate monocyte: 1.2;myeloid DC: 1.6" "Group enriched" "Detected in many" 16 "dendritic cells: 1.6;monocytes: 1.5" "Cell line enhanced" "Detected in many" "AF22: 50.0;CACO-2: 112.6;HaCaT: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002573, HPA037467, HPA037468" Enhanced Supported Approved Nucleoli,Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Vesicles" "CAB002573: AB_564088, HPA037467: AB_10795027, HPA037468: AB_10671371" "unprognostic (1.23e-1)" "unprognostic (2.15e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (7.70e-2)" "unprognostic (3.89e-3)" "unprognostic (2.36e-1)" "unprognostic (1.24e-1)" "unprognostic (2.84e-2)" "unprognostic (4.17e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.17e-2)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" 30.7 16.4 500.4 7.4 544.2 3.3 17.7 549.4 776.8 8.7 400.6 3.0 0.5 1.6 1.1 10.5 6.0 8.0 45.4 514.6 502.5 2.2 3.8 10.2 17.4 477.6 510.1 12.6 5.0 2.2 18.1 20.3 502.4 3.2 1.1 221.1 4.7 4.7 14.1 6.0 3.2 4.1 495.4 9.3 2.2 1.2 532.8 3.6 3.4 9.2 5.4 7.0 5.3 494.9 1.3 0.2 50.0 5.3 5.9 14.3 37.7 0.3 0.0 2.4 4.9 112.6 5.6 0.0 27.8 2.3 1.0 71.4 16.9 9.1 2.2 1.8 33.0 0.0 0.5 0.0 2.5 1.3 0.6 26.9 34.5 14.4 5.3 1.8 0.0 1.1 0.0 0.2 8.7 0.2 0.1 0.1 6.0 0.1 5.9 0.0 0.5 0.0 0.1 3.1 4.7 0.0 5.1 14.6 2.1 24.4 0.2 3.1 0.0 6.2 10.3 0.1 20.7 0.0 0.0 0.3 21.7 37.7 12.6 0.0 1.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 500.4 544.2 549.4 776.8 514.6 502.5 477.6 510.1 502.4 495.4 532.8 494.9 1.1 3.2 0.5 1735.2 0.7 10.7 14.3 19.0 83.1 7.1 3.7 3.4 36.0 0.0 3.1 0.0 2.1 32.9 0.1 0.0 0.0 0.8 0.7 16.3 1.2 8.9 0.0 0.8 2.6 0.0 15.9 7.8 2.0 11.7 0.0 0.2 1.1 0.5 41.2 3.3 4.7 0.0 0.0 77.6 5.9 4.1 4.4 59.6 7.2 332.6 3.3 472.6 0.0 237.7 249.0 0.3 0.0 0.0 0.7 5.2 0.0 0.0 5.3 19.1 6.6 2.6 3.1 0.3 0.3 32.7 7.1 9.2 1.0 20.7 0.0 3.6 SLC22A16 "CT2, FLIPT2, OAT6, OKB1" ENSG00000004809 "Solute carrier family 22 member 16" Q86VW1 6 110424687-110476641 "Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 20.5;testis: 21.4" "Group enriched" "Detected in some" 10 "Early spermatids: 34.9;Erythroid cells: 60.4;Late spermatids: 31.8;Spermatocytes: 43.1" "Cancer enriched" "Detected in single" 5 "endometrial cancer: 0.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.7;classical monocyte: 6.9" "Group enriched" "Detected in many" 56 "dendritic cells: 4.0;granulocytes: 5.7;monocytes: 6.9" "Group enriched" "Detected in some" 18 "NB-4: 16.9;REH: 14.6;THP-1: 53.1;U-937: 30.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036902 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA036902: AB_10672274" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (5.11e-3)" "unprognostic (2.19e-3)" "unprognostic (2.70e-4)" "unprognostic (1.45e-1)" "unprognostic (8.15e-2)" "unprognostic (6.93e-2)" "unprognostic (1.48e-2)" "unprognostic (4.98e-2)" "unprognostic (1.02e-3)" "unprognostic (2.49e-1)" "unprognostic (2.61e-6)" "unprognostic (5.78e-4)" "unprognostic (2.72e-2)" "unprognostic (2.74e-2)" "unprognostic (2.65e-2)" 0.3 0.0 0.1 0.6 0.2 20.5 0.1 0.2 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.2 0.2 0.0 0.0 3.8 0.0 0.5 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.8 0.2 0.5 0.0 21.4 0.1 1.2 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 53.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 30.9 0.0 5.7 6.9 1.3 0.0 1.5 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.5 0.1 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.3 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.9 0.4 0.1 0.0 0.0 60.4 0.1 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 1.8 0.5 31.8 1.5 1.1 0.0 0.0 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.3 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 43.1 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 SLC22A18AS "BWR1B, BWSCR1B, ORCTL2S, p27-BWR1B, SLC22A1LS" ENSG00000254827 "Solute carrier family 22 member 18 antisense" Q8N1D0 11 2887344-2903575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 17.7;kidney: 11.1;liver: 14.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 163.3;Paneth cells: 124.4;Proximal enterocytes: 75.7;Proximal tubular cells: 104.0;Syncytiotrophoblasts: 80.7;Undifferentiated cells: 48.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 7.0" "Group enriched" "Detected in many" 8 "dendritic cells: 3.9;granulocytes: 4.0;monocytes: 7.0" "Cell line enhanced" "Detected in some" "A549: 9.4;CAPAN-2: 9.4;MCF7: 18.8;OE19: 8.4;SK-MEL-30: 35.8;WM-115: 14.8" HPA068288 Enhanced Approved Nucleoplasm No NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA068288: AB_2685969" "unprognostic (1.43e-1)" "unprognostic (9.21e-2)" "unprognostic (3.36e-1)" "unprognostic (8.05e-2)" "unprognostic (1.33e-3)" "unprognostic (3.16e-2)" "unprognostic (5.14e-3)" "unprognostic (9.76e-2)" "unprognostic (1.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.10e-2)" "unprognostic (1.48e-2)" "unprognostic (9.52e-2)" "unprognostic (1.77e-1)" "unprognostic (2.39e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" 3.2 0.6 0.5 2.2 0.6 0.2 0.7 0.5 1.7 0.7 0.5 17.7 13.4 0.8 0.4 1.2 0.4 1.7 0.3 0.6 1.0 11.1 14.9 0.6 0.4 0.9 0.9 0.4 0.3 0.0 0.3 2.3 1.1 0.8 10.2 0.3 1.8 0.1 0.1 1.1 9.7 0.7 0.8 0.7 1.6 0.5 0.8 0.1 0.3 0.0 0.1 0.7 0.9 1.1 1.2 9.4 0.3 0.5 0.0 0.0 0.9 0.5 0.4 0.0 0.2 2.2 9.4 0.0 0.8 0.0 0.6 0.5 0.0 0.3 0.0 0.4 0.1 0.0 0.8 5.8 0.7 0.0 0.1 0.1 0.3 0.0 0.6 0.4 0.3 0.5 0.0 0.9 0.0 18.8 0.0 0.4 0.2 8.4 0.3 0.3 0.0 1.0 0.8 0.0 0.1 0.3 0.9 0.4 35.8 0.2 0.0 0.9 1.9 0.0 0.7 0.3 0.2 0.0 0.0 0.2 0.2 2.6 14.8 4.0 7.0 1.2 0.2 3.9 0.1 0.0 0.1 0.2 3.9 0.0 0.0 0.1 1.6 0.4 2.9 0.0 0.6 2.4 0.5 0.6 0.5 1.7 0.6 1.0 0.9 0.9 1.1 0.8 0.8 1.1 0.6 0.0 0.5 0.0 1.3 0.5 1.1 6.3 1.2 0.0 1.2 0.9 0.4 1.5 2.7 7.3 0.0 19.5 0.4 163.3 9.8 1.7 0.1 0.1 0.3 0.7 9.1 3.2 0.4 0.8 9.8 1.4 2.6 0.5 1.3 0.0 2.9 22.7 17.7 0.0 0.1 26.2 6.1 6.3 5.5 0.2 0.3 6.4 3.6 0.0 4.6 0.0 0.0 0.0 0.1 2.4 124.4 0.0 0.0 1.0 75.7 104.0 1.0 0.0 0.0 0.0 0.6 0.1 0.4 2.1 1.1 80.7 0.9 0.8 48.5 2.5 SLC27A1 "ACSVL5, FATP, FATP1, FLJ00336, MGC71751" ENSG00000130304 "Solute carrier family 27 member 1" Q6PCB7 19 17468769-17506168 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Oligodendrocytes: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 27.7;SK-MEL-30: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076520 Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Mitochondria, Cytosol" "HPA076520: AB_2732311" "unprognostic (1.48e-3)" "unprognostic (3.03e-2)" "unprognostic (5.72e-3)" "unprognostic (5.84e-2)" "unprognostic (2.16e-3)" "unprognostic (4.36e-2)" "unprognostic (8.56e-2)" "unprognostic (3.36e-2)" "unprognostic (9.03e-2)" "unprognostic (1.85e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "prognostic favorable (4.70e-4)" "unprognostic (5.01e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" 18.5 24.2 32.9 4.5 41.5 1.5 19.3 37.3 39.0 22.0 45.9 15.2 3.6 13.1 2.9 8.5 17.0 8.2 29.0 32.0 32.8 10.9 7.9 10.4 4.7 41.1 40.3 33.0 14.4 17.7 19.3 6.2 38.6 23.2 1.8 4.0 24.1 10.3 24.9 14.4 7.6 3.9 34.4 10.5 13.7 17.5 35.9 2.2 16.8 12.4 1.6 13.9 14.0 46.7 6.2 3.0 4.1 9.8 27.7 15.2 3.5 4.4 11.2 4.8 7.2 0.5 18.2 2.1 8.1 7.2 4.3 7.3 0.4 6.8 1.3 2.4 1.4 1.2 0.5 2.3 5.4 0.5 6.4 14.1 4.6 4.8 1.9 19.7 3.3 3.9 0.8 1.3 3.2 2.5 3.3 4.9 1.2 6.0 5.2 4.7 3.2 1.4 3.2 1.8 1.4 2.9 3.0 1.5 47.8 2.5 5.2 1.6 2.1 9.4 6.1 7.5 3.0 4.0 3.1 0.7 9.6 5.3 6.7 0.0 9.2 0.2 1.4 4.0 2.6 0.4 1.0 1.7 6.3 0.3 1.3 1.7 0.0 1.6 1.8 6.5 0.7 4.6 32.9 41.5 37.3 39.0 32.0 32.8 41.1 40.3 38.6 34.4 35.9 46.7 19.7 3.2 11.9 84.5 1.8 6.6 14.1 12.7 10.2 8.4 15.5 26.9 19.5 11.5 11.1 9.2 27.1 4.3 8.3 1.2 1.9 11.1 1.1 8.4 6.9 7.8 5.4 0.8 16.1 4.8 15.6 10.4 9.2 4.9 2.5 8.4 10.4 8.1 26.1 6.7 23.9 3.0 6.1 22.4 4.0 2.5 21.5 13.4 8.8 15.0 14.7 11.6 4.1 37.2 67.5 5.2 0.6 11.7 1.7 12.0 0.1 3.6 16.1 17.7 6.6 10.9 7.3 9.1 5.8 5.0 4.5 2.3 4.9 13.8 2.2 8.7 SLC2A9 "Glut9, GLUTX, URATv1" ENSG00000109667 "Solute carrier family 2 member 9" Q9NRM0 4 9771153-10054936 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 29.3;liver: 21.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 27.4;Proximal tubular cells: 72.6" "Cancer enhanced" "Detected in many" "renal cancer: 6.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 36.9;myeloid DC: 30.5" "Group enriched" "Detected in many" 30 "dendritic cells: 30.5;monocytes: 36.9" "Cell line enhanced" "Detected in some" "HBEC3-KT: 48.1;Hep G2: 23.6;hTCEpi: 19.9;THP-1: 20.5;U-937: 13.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA066229, HPA075669" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA066229: AB_2685639, HPA075669: " "unprognostic (3.21e-1)" "unprognostic (8.99e-3)" "unprognostic (1.25e-2)" "unprognostic (2.01e-1)" "unprognostic (2.14e-2)" "unprognostic (2.56e-2)" "unprognostic (8.94e-2)" "unprognostic (6.94e-2)" "unprognostic (2.86e-2)" "unprognostic (1.28e-2)" "unprognostic (3.16e-1)" "unprognostic (2.23e-1)" "prognostic favorable (1.32e-11)" "unprognostic (1.01e-1)" "unprognostic (3.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.20e-1)" 1.6 2.6 1.0 2.0 1.2 2.1 4.2 1.3 1.2 2.5 2.7 1.8 10.7 1.4 2.4 5.2 3.5 2.4 2.3 1.1 1.6 29.3 21.4 4.2 2.0 2.3 1.5 1.6 1.0 2.4 1.4 7.6 2.0 3.5 1.6 1.2 16.6 18.8 0.5 2.2 8.4 2.0 1.8 1.8 1.0 0.7 2.0 4.2 2.7 0.5 1.4 6.4 4.0 3.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.1 0.0 0.3 2.4 0.0 3.5 0.7 0.0 7.3 0.0 48.1 0.0 8.2 0.3 0.0 0.0 23.6 1.6 0.1 6.3 3.4 19.9 0.0 4.8 0.0 0.1 0.8 0.0 0.1 0.1 0.0 0.3 2.4 0.0 0.4 0.1 1.5 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 20.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.5 0.1 0.0 36.9 0.9 0.3 7.6 0.3 0.3 0.3 0.1 30.5 0.1 0.2 0.1 1.1 0.2 0.9 12.2 0.2 9.1 1.0 1.2 1.3 1.2 1.1 1.6 2.3 1.5 2.0 1.8 2.0 3.0 1.4 0.0 0.0 8.1 1.3 0.9 13.4 27.4 6.2 0.0 4.6 6.1 2.4 0.0 5.7 3.7 2.1 18.7 0.5 1.7 3.9 0.5 5.1 4.1 2.1 1.5 0.0 1.3 4.4 1.1 1.8 1.6 1.1 11.5 1.3 0.5 2.2 5.2 10.3 0.0 5.6 0.9 10.2 8.7 3.7 3.4 0.0 8.8 0.0 15.9 4.4 1.2 1.0 10.6 1.1 0.6 0.5 0.4 0.3 2.0 8.1 72.6 3.0 0.4 0.0 4.6 1.6 1.1 1.9 5.4 0.6 8.5 0.9 0.7 2.5 7.7 SLC35A1 "CMPST, hCST" ENSG00000164414 "Solute carrier family 35 member A1" P78382 6 87470623-87512336 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 103.0;Inhibitory neurons: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "unprognostic (3.04e-2)" "unprognostic (1.93e-1)" "unprognostic (6.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.82e-1)" "unprognostic (4.07e-2)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (1.58e-2)" "unprognostic (3.01e-3)" "unprognostic (7.26e-2)" "unprognostic (3.85e-1)" "prognostic unfavorable (2.70e-6)" "unprognostic (2.85e-1)" "unprognostic (8.51e-2)" "unprognostic (5.48e-2)" "unprognostic (1.04e-1)" 16.4 24.0 24.6 15.6 25.4 11.2 30.9 28.3 31.6 27.8 28.5 39.6 18.8 24.9 22.1 13.9 20.2 19.5 16.0 26.0 25.5 21.2 32.9 37.6 17.9 24.3 24.1 23.1 15.8 23.7 18.9 19.7 24.4 36.8 47.6 14.4 31.6 16.5 13.8 24.9 21.5 22.0 24.5 19.0 29.2 13.2 24.9 16.3 16.9 15.7 16.3 21.5 16.7 25.4 4.8 11.5 20.4 24.1 54.4 49.3 16.4 13.9 12.2 11.4 15.6 9.9 86.0 17.6 16.8 17.3 31.7 18.5 24.8 11.3 14.6 25.3 18.4 20.0 14.7 17.8 35.7 26.3 13.3 25.3 26.6 13.5 26.1 26.8 27.5 25.5 26.1 28.4 17.0 44.6 7.3 39.6 11.0 60.4 18.6 22.4 19.9 19.0 35.6 20.4 13.3 14.6 25.7 47.4 23.2 23.3 42.2 53.0 26.0 16.4 11.1 18.2 11.3 21.1 32.7 6.5 13.7 46.2 23.7 52.1 54.1 22.8 17.5 42.8 27.1 17.8 18.7 21.5 46.9 16.7 23.7 22.3 13.2 17.5 44.2 17.3 26.8 36.9 24.6 25.4 28.3 31.6 26.0 25.5 24.3 24.1 24.4 24.5 24.9 25.4 14.7 44.8 33.6 19.2 11.7 14.8 18.1 37.1 18.8 6.2 23.6 16.6 6.2 20.0 25.5 16.5 12.5 25.0 16.1 27.1 7.9 10.1 10.6 6.3 9.9 15.8 15.0 8.2 103.0 8.9 19.7 19.2 13.3 6.8 21.6 14.2 42.8 20.7 15.6 11.8 87.2 73.5 48.8 28.2 11.1 7.1 16.4 15.8 21.4 24.4 27.4 17.3 16.5 42.3 26.9 11.5 19.0 19.2 9.4 17.5 14.5 11.3 25.4 7.0 19.7 8.9 16.9 9.6 14.2 9.0 14.8 27.5 14.9 12.5 32.7 8.9 SLC39A11 C17orf26 ENSG00000133195 "Solute carrier family 39 member 11" Q8N1S5 17 72645949-73092712 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 205.3;Excitatory neurons: 107.7;Oligodendrocytes: 360.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 217.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021455 Approved Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA021455: AB_2670710" "unprognostic (2.29e-2)" "unprognostic (2.75e-1)" "unprognostic (1.25e-1)" "unprognostic (2.19e-1)" "unprognostic (1.61e-1)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.44e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-1)" "unprognostic (3.45e-3)" "unprognostic (2.30e-1)" "unprognostic (1.57e-3)" "unprognostic (5.26e-2)" "unprognostic (1.17e-1)" "unprognostic (4.96e-3)" "unprognostic (3.85e-2)" 12.6 7.8 14.0 10.8 27.8 21.2 17.4 22.5 17.2 14.9 9.5 24.0 20.3 5.5 15.7 15.5 9.1 11.0 4.9 14.1 17.9 13.4 39.4 10.9 8.8 25.7 23.7 3.4 29.3 4.7 2.9 8.7 24.0 7.7 24.1 2.3 30.3 8.0 4.5 14.2 22.8 7.3 16.9 7.9 48.2 6.8 23.9 5.5 36.1 3.5 12.4 12.5 9.3 35.3 20.5 36.8 4.3 17.2 30.7 24.8 24.4 21.6 19.0 9.7 13.0 13.7 90.7 25.4 21.5 22.1 15.4 17.2 6.2 10.9 14.8 27.6 12.8 23.8 9.9 16.3 18.3 25.4 217.5 21.2 20.3 20.1 11.6 10.6 10.1 13.1 12.6 31.0 12.4 28.9 16.3 55.1 3.5 62.4 15.6 10.9 16.3 21.5 16.0 20.9 10.2 13.8 11.6 84.7 12.7 16.8 58.4 34.9 8.5 19.0 17.7 16.3 13.4 24.9 12.2 17.9 30.8 50.6 11.1 19.3 39.9 26.0 16.7 40.4 10.9 16.7 12.5 12.5 37.9 9.8 8.8 12.1 6.6 22.6 33.1 26.8 17.1 18.1 14.0 27.8 22.5 17.2 14.1 17.9 25.7 23.7 24.0 16.9 23.9 35.3 4.9 0.0 6.3 205.3 7.6 4.5 5.3 5.6 10.2 2.6 13.7 5.5 2.3 4.3 8.6 3.7 0.0 5.6 6.9 15.8 0.0 9.4 18.5 5.6 3.6 4.0 8.4 9.9 107.7 14.1 17.4 4.7 29.0 9.5 29.9 7.9 3.6 30.1 26.3 5.0 32.1 79.0 10.2 21.0 5.6 66.7 4.1 14.4 10.6 64.6 19.6 4.1 8.2 22.6 360.3 9.1 20.5 3.4 15.1 6.0 24.8 11.5 7.8 1.6 13.1 2.6 7.1 2.0 2.9 10.3 4.4 4.9 5.4 4.4 18.3 7.5 SLC46A2 "Ly110, TSCOT" ENSG00000119457 "Solute carrier family 46 member 2" Q9BY10 9 112878920-112890876 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 16.5;lung: 10.4;lymphoid tissue: 16.0;skin 1: 24.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 39.8;Endometrial ciliated cells: 15.8;Glandular and luminal cells: 6.9;Kupffer cells: 11.8;monocytes: 12.4" "Cancer enhanced" "Detected in some" "lung cancer: 1.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 24.6;intermediate monocyte: 12.1" "Lineage enriched" "Detected in many" 5 "monocytes: 24.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020098 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 11: Alveolar cells - Smell perception" "HPA020098: AB_2670363" "unprognostic (1.26e-1)" "unprognostic (5.15e-3)" "unprognostic (1.10e-2)" "unprognostic (1.53e-3)" "unprognostic (3.57e-3)" "unprognostic (2.10e-2)" "unprognostic (4.56e-1)" "unprognostic (2.18e-1)" "unprognostic (8.10e-2)" "unprognostic (1.50e-3)" "unprognostic (3.50e-1)" "unprognostic (1.38e-1)" "unprognostic (1.77e-2)" "unprognostic (2.37e-1)" "unprognostic (2.71e-2)" "unprognostic (1.83e-1)" "unprognostic (7.82e-2)" 0.1 0.0 0.1 0.6 0.1 0.1 0.9 0.5 0.2 16.5 0.0 0.0 0.0 3.0 4.7 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 10.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 1.5 0.0 24.1 0.0 0.4 0.0 0.9 0.0 0.6 0.5 16.0 0.0 0.0 0.1 3.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.1 12.1 0.1 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.0 10.1 0.2 0.0 6.6 0.1 0.1 0.5 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.5 0.3 0.0 0.0 39.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.7 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 15.8 0.8 0.3 0.0 0.0 0.9 0.0 0.0 0.2 0.0 6.9 0.0 0.0 0.4 0.1 2.1 0.0 0.4 0.0 0.0 11.8 1.8 4.4 0.0 4.1 0.0 0.0 12.4 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 SLC49A3 "FLJ22269, LP2561, MFSD7" ENSG00000169026 "Solute carrier family 49 member 3" Q6UXD7 4 681829-689271 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 12.8;Breast glandular cells: 14.6;Collecting duct cells: 14.7;Ductal cells: 19.2;Extravillous trophoblasts: 33.9;Hofbauer cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 8.7;CAPAN-2: 5.8;SK-BR-3: 8.2;T-47d: 25.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043593 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" "HPA043593: AB_10959611" "unprognostic (1.10e-2)" "unprognostic (1.91e-1)" "unprognostic (8.77e-2)" "unprognostic (4.70e-2)" "unprognostic (9.40e-2)" "unprognostic (1.84e-3)" "unprognostic (2.22e-1)" "unprognostic (1.56e-2)" "unprognostic (1.83e-1)" "unprognostic (2.56e-1)" "unprognostic (9.22e-2)" "unprognostic (2.08e-1)" "prognostic favorable (2.66e-5)" "unprognostic (8.35e-2)" "unprognostic (4.92e-2)" "unprognostic (7.48e-2)" "unprognostic (1.11e-1)" 8.2 3.2 2.4 4.4 2.1 3.5 9.0 2.7 3.0 4.5 3.5 4.2 5.9 3.4 4.2 4.4 3.3 3.7 8.3 1.7 2.3 8.3 5.8 8.1 3.0 3.2 2.2 1.2 4.8 4.6 1.9 2.7 3.0 5.0 2.3 12.6 8.4 2.1 3.0 10.2 5.9 2.1 2.7 8.5 8.4 8.9 3.5 0.6 8.5 1.9 1.7 4.3 4.9 2.9 0.1 0.1 2.7 1.9 1.9 3.7 8.7 1.0 0.0 0.7 0.6 0.4 5.8 0.1 0.2 4.5 0.4 0.2 0.0 0.0 0.2 0.6 0.6 1.6 0.7 0.2 0.8 0.0 1.2 2.5 0.0 3.4 0.0 0.0 1.3 0.3 0.4 0.5 0.0 0.1 0.1 0.7 0.3 0.4 0.5 0.0 0.3 0.6 0.0 0.3 0.9 0.7 0.0 8.2 0.5 0.5 25.8 1.6 0.3 0.8 0.3 0.4 0.3 2.8 1.6 0.1 0.3 0.7 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.4 0.2 0.0 0.1 0.3 2.4 2.1 2.7 3.0 1.7 2.3 3.2 2.2 3.0 2.7 3.5 2.9 12.8 3.2 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.6 8.4 0.0 0.0 1.8 14.7 0.0 0.7 3.1 0.0 1.9 19.2 0.0 2.1 6.0 4.3 0.0 0.0 0.0 0.4 33.9 4.3 0.0 4.1 0.0 0.8 0.0 0.0 35.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 3.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 4.9 0.7 0.5 0.0 0.0 SMARCD3 "BAF60C, CRACD3, Rsc6p" ENSG00000082014 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3" Q6STE5 7 151238764-151277896 "Metabolic proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 126.4;skeletal muscle: 129.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 67.5;Peritubular cells: 88.4;Sertoli cells: 65.7" "Cancer enhanced" "Detected in all" "glioma: 28.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.5" "Group enriched" "Detected in many" 6 "dendritic cells: 1.6;granulocytes: 1.9;monocytes: 5.5" "Cell line enhanced" "Detected in many" "AN3-CA: 69.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063955, HPA065517" Uncertain Enhanced Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 47: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA063955: AB_2685159, HPA065517: AB_2685500" "unprognostic (1.23e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.38e-3)" "unprognostic (4.67e-1)" "unprognostic (1.41e-3)" "unprognostic (2.24e-2)" "unprognostic (3.52e-2)" "unprognostic (1.63e-1)" "unprognostic (3.50e-1)" "unprognostic (2.08e-3)" "unprognostic (9.18e-2)" "unprognostic (1.02e-1)" "unprognostic (2.05e-3)" "unprognostic (1.34e-1)" "unprognostic (3.35e-3)" "unprognostic (1.29e-1)" 20.7 40.3 104.0 5.0 101.9 7.1 22.1 70.7 126.4 25.0 59.8 25.2 3.0 22.8 14.7 8.4 30.6 14.6 78.9 105.3 90.4 18.8 2.8 18.8 4.6 79.5 89.8 37.6 14.3 27.2 42.2 5.7 83.2 27.7 3.8 10.0 14.3 23.2 129.0 11.5 11.0 13.4 72.4 9.2 18.3 17.4 99.9 1.9 18.1 69.4 2.5 22.7 18.2 84.8 0.8 6.1 19.6 69.3 30.0 13.3 1.6 13.3 13.0 7.5 4.3 4.5 4.2 7.7 4.7 20.4 3.0 1.3 15.7 1.3 3.0 2.4 10.2 0.0 4.5 1.4 25.9 0.4 12.5 31.8 1.8 2.4 0.2 32.7 1.5 19.5 16.4 2.5 39.5 8.3 1.3 10.3 6.1 2.0 2.5 0.5 31.7 0.3 6.6 0.0 11.2 22.6 12.4 2.1 9.5 3.1 2.0 19.7 2.6 6.1 7.7 15.7 4.9 16.1 0.0 6.5 14.2 17.6 21.6 0.4 5.5 0.0 0.1 1.3 0.1 0.1 0.5 0.0 1.6 0.0 0.3 0.5 1.9 0.0 0.2 0.0 0.4 1.3 104.0 101.9 70.7 126.4 105.3 90.4 79.5 89.8 83.2 72.4 99.9 84.8 7.5 6.4 21.7 33.6 0.7 10.7 38.3 3.1 47.8 15.2 28.5 29.6 67.5 21.5 4.6 11.0 4.2 0.4 1.2 0.2 31.3 24.8 2.5 3.9 24.4 5.2 3.5 1.3 16.7 2.6 0.5 28.0 1.5 3.4 2.5 44.3 2.9 0.5 3.6 11.8 23.9 0.3 0.0 17.0 5.7 14.0 50.7 16.0 7.2 8.4 19.7 23.7 0.0 16.1 7.4 2.8 0.1 88.4 0.1 14.6 0.0 2.1 4.7 5.7 65.7 40.9 56.9 1.7 20.0 1.5 4.7 1.1 4.7 22.8 0.2 9.0 SMIM4 C3orf78 ENSG00000168273 "Small integral membrane protein 4" Q8WVI0 3 52534013-52579237 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 121.9;skeletal muscle: 130.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 252.4;Distal tubular cells: 213.2;Proximal tubular cells: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047771 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA047771: AB_2680150" "unprognostic (3.76e-3)" "unprognostic (3.19e-2)" "unprognostic (4.54e-2)" "unprognostic (4.89e-1)" "unprognostic (2.40e-1)" "unprognostic (1.48e-2)" "unprognostic (9.89e-2)" "prognostic favorable (1.78e-5)" "unprognostic (3.25e-2)" "unprognostic (4.25e-2)" "prognostic favorable (5.00e-4)" "unprognostic (6.35e-2)" "prognostic favorable (1.63e-4)" "unprognostic (8.72e-3)" "unprognostic (2.28e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-2)" 22.6 121.9 14.6 12.9 15.3 7.4 22.1 21.8 20.5 16.0 20.5 19.1 12.3 14.3 10.4 16.3 14.5 3.7 100.3 15.3 15.5 37.3 20.2 20.3 10.5 15.6 18.2 41.5 25.7 31.6 56.4 6.1 16.9 26.2 10.4 13.9 28.9 13.6 130.3 20.1 15.0 5.0 15.0 15.8 20.4 17.3 15.4 6.6 48.6 50.2 8.7 20.2 13.3 18.0 58.7 19.0 22.9 58.5 26.5 13.7 47.0 25.9 12.0 29.2 25.3 24.6 15.4 25.1 11.6 10.9 29.4 30.2 7.6 20.9 11.8 16.9 60.1 23.6 58.2 50.2 40.1 28.4 31.6 29.6 12.7 24.6 17.7 15.8 26.8 27.0 31.9 36.4 19.9 25.4 26.4 39.4 39.1 31.9 42.4 18.1 22.2 50.1 17.0 25.2 24.9 31.4 50.6 16.5 52.6 12.9 17.0 23.6 24.0 16.0 53.1 76.4 53.5 42.3 50.6 57.3 87.9 52.2 22.5 8.1 44.1 17.3 19.1 35.8 18.8 24.6 27.3 23.9 49.7 22.7 29.1 27.0 1.6 22.5 15.2 26.5 29.6 20.0 14.6 15.3 21.8 20.5 15.3 15.5 15.6 18.2 16.9 15.0 15.4 18.0 35.4 48.1 46.3 1.3 30.3 27.1 37.3 52.2 41.5 17.6 80.9 84.1 252.4 60.1 63.1 53.3 12.5 42.9 26.6 58.3 213.2 52.9 21.9 71.9 30.6 32.8 79.3 22.1 1.9 86.1 24.7 36.0 34.1 48.9 59.5 16.9 55.6 160.4 116.4 3.3 2.1 62.9 30.5 80.8 46.7 15.1 65.0 51.1 37.4 0.0 28.5 102.8 15.5 2.5 3.2 57.8 39.9 101.2 19.7 19.7 89.5 215.6 52.1 15.3 46.0 22.8 56.8 9.8 14.2 34.8 34.5 27.6 25.8 44.3 73.5 23.6 SNCG "BCSG1, persyn, SR" ENSG00000173267 "Synuclein gamma" O76070 10 86958599-86963258 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 268.3;brain: 411.2" "Cell type enhanced" "Detected in many" "Adipocytes: 164.9;Breast myoepithelial cells: 156.1;Endothelial cells: 143.3;Hepatic stellate cells: 206.0;Smooth muscle cells: 234.3;Urothelial cells: 358.3" "Group enriched" "Detected in all" 8 "ovarian cancer: 84.1;urothelial cancer: 301.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 748.2;RT4: 483.5;T-47d: 151.7;TIME: 160.9" "Region enhanced" "Detected in all" "pons and medulla: 279.9" "Low region specificity" "Detected in many" "CAB001452, HPA014404, CAB040581, CAB080022" Enhanced Supported NA NA 23000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB001452: AB_564020, CAB040581: , CAB080022: , HPA014404: AB_1857715" "unprognostic (2.06e-1)" "unprognostic (2.58e-1)" "unprognostic (6.87e-3)" "unprognostic (1.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (4.76e-3)" "unprognostic (8.99e-2)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-3)" "unprognostic (3.75e-1)" "prognostic unfavorable (2.29e-8)" "prognostic unfavorable (7.15e-4)" "unprognostic (2.35e-1)" "unprognostic (2.36e-2)" "unprognostic (3.77e-3)" 208.2 268.3 215.6 11.9 150.8 0.0 98.1 199.9 313.3 33.3 44.0 27.0 9.2 22.9 15.1 25.4 64.5 12.7 31.7 190.2 387.7 22.3 4.3 13.9 11.6 411.2 276.4 42.1 5.3 3.3 11.1 11.9 357.8 36.6 4.9 52.7 22.9 101.6 14.6 28.6 18.8 10.1 155.3 64.2 16.4 5.4 304.7 9.0 20.3 13.7 25.6 204.8 38.9 148.8 2.6 6.8 0.7 1.1 0.3 3.9 0.7 0.8 0.0 0.0 0.0 1.1 748.2 0.0 22.6 1.4 0.0 71.0 0.0 3.4 0.0 0.1 1.4 3.6 109.6 2.0 1.4 0.0 1.8 2.8 55.5 0.0 0.6 0.2 49.8 0.0 5.3 0.0 0.0 0.6 0.2 0.4 11.3 0.0 0.4 0.0 0.4 0.3 0.2 483.5 0.1 0.0 6.5 8.7 0.9 1.0 151.7 0.3 160.9 1.1 3.7 0.3 0.0 0.2 0.0 0.0 0.8 3.6 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 215.6 150.8 199.9 313.3 190.2 387.7 411.2 276.4 357.8 155.3 304.7 148.8 164.9 0.0 0.0 7.5 1.5 28.8 65.9 16.3 11.4 32.2 61.1 156.1 1.9 8.6 14.6 55.2 6.2 19.4 2.8 0.1 125.2 3.6 0.6 0.4 0.8 143.3 0.0 2.7 9.9 1.1 0.6 14.2 0.5 0.6 0.0 0.1 206.0 0.8 5.5 87.5 28.0 0.0 20.3 1.8 27.3 3.7 59.0 2.2 23.2 6.5 0.9 66.4 0.0 4.5 7.5 4.7 2.2 9.8 0.0 14.2 0.3 1.3 2.4 109.3 92.1 2.5 234.3 0.6 0.7 2.6 19.7 6.2 2.7 16.9 0.0 358.3 SNX30 ATG24A ENSG00000148158 "Sorting nexin family member 30" Q5VWJ9 9 112750760-112881671 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 77.9;Oligodendrocytes: 91.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019346 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli, Cytosol" "HPA019346: AB_2286395" "unprognostic (1.67e-2)" "unprognostic (1.38e-1)" "unprognostic (1.08e-1)" "unprognostic (3.61e-1)" "unprognostic (3.61e-1)" "unprognostic (3.69e-1)" "unprognostic (8.05e-3)" "unprognostic (2.04e-3)" "unprognostic (4.48e-2)" "unprognostic (3.59e-3)" "unprognostic (3.39e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.01e-7)" "unprognostic (4.48e-3)" "unprognostic (1.18e-1)" "unprognostic (7.51e-2)" "unprognostic (1.41e-2)" 3.5 3.6 8.0 7.3 16.5 8.4 6.8 9.7 12.3 9.1 0.0 10.2 7.1 5.5 3.4 3.8 3.1 4.7 3.0 7.9 13.5 21.2 4.6 21.3 8.6 14.5 12.9 5.7 4.6 5.2 3.0 4.5 12.2 3.4 10.3 4.0 5.0 3.5 2.0 4.8 8.2 6.5 8.6 7.0 4.2 11.9 16.1 3.8 2.6 2.1 8.1 4.0 3.2 25.8 8.2 5.0 8.5 6.8 10.5 9.6 7.2 6.9 14.2 5.7 5.4 18.1 1.9 13.6 5.7 17.9 10.2 9.6 10.4 4.1 8.8 4.4 4.9 4.2 4.6 7.3 7.5 4.2 7.2 7.8 5.6 8.8 6.5 14.4 4.9 3.4 6.7 7.5 7.8 5.7 2.8 4.9 9.4 13.2 5.2 5.9 19.9 3.5 11.1 14.2 12.6 4.0 9.0 12.3 17.6 8.7 9.2 7.4 5.6 8.4 9.0 25.0 5.9 19.6 19.5 6.3 10.8 3.9 16.9 0.0 2.0 0.6 0.2 0.7 0.6 0.0 0.3 0.4 1.6 0.2 0.2 0.2 0.2 0.3 0.8 0.2 0.6 0.7 8.0 16.5 9.7 12.3 7.9 13.5 14.5 12.9 12.2 8.6 16.1 25.8 4.4 6.4 77.9 11.4 3.5 8.2 2.0 3.1 7.4 5.9 10.5 5.5 4.3 2.8 7.6 5.5 10.4 0.6 3.6 26.2 5.9 2.6 9.1 16.2 7.5 4.8 4.8 6.6 39.0 3.2 2.1 5.3 5.6 20.1 7.0 15.6 8.9 7.7 13.4 8.4 24.1 10.8 2.0 22.4 17.0 8.1 5.6 19.8 21.4 36.5 22.3 2.4 2.1 22.6 91.2 4.4 20.3 7.9 5.8 2.5 11.9 34.2 2.3 3.1 0.0 4.7 2.8 6.6 10.0 7.3 11.1 0.4 5.7 3.7 9.6 6.3 SOAT1 "ACAT, SOAT, STAT" ENSG00000057252 "Sterol O-acyltransferase 1" P35610 1 179293714-179358680 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "adrenal gland: 165.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009533, HPA047171" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum" "CAB009533: AB_633499, HPA047171: AB_2679967" "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.81e-3)" "unprognostic (7.81e-3)" "unprognostic (3.29e-1)" "unprognostic (9.00e-2)" "unprognostic (9.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.45e-3)" "unprognostic (7.02e-3)" "unprognostic (4.67e-3)" "unprognostic (9.64e-2)" "unprognostic (4.67e-2)" "unprognostic (1.82e-1)" 14.6 165.3 4.2 18.1 5.7 17.5 8.2 5.5 6.6 13.7 9.0 13.0 12.2 11.7 6.6 4.8 17.9 20.5 5.4 3.3 6.8 12.7 14.1 20.9 15.1 10.1 6.1 10.7 27.0 13.4 6.3 19.1 8.0 27.7 14.8 10.3 39.4 9.3 4.0 5.7 12.7 16.5 8.0 15.1 16.3 11.0 6.7 8.1 9.2 3.7 13.1 11.7 4.5 12.8 74.6 34.1 27.7 41.0 104.7 56.6 147.3 35.1 61.7 76.2 88.3 35.2 82.6 42.0 53.9 64.4 92.6 26.8 88.6 20.9 81.8 48.0 18.2 19.5 26.7 36.9 42.9 33.5 7.5 45.4 13.3 89.2 75.8 32.1 33.3 50.5 42.7 21.0 120.0 15.9 35.9 10.8 13.4 11.8 11.2 44.4 35.8 24.4 66.1 45.9 8.4 21.5 54.3 22.9 20.1 32.3 24.0 22.8 31.9 89.8 43.1 99.5 78.2 29.4 115.3 35.5 35.7 17.9 170.6 55.4 53.4 1.6 26.4 34.2 25.0 12.9 24.0 24.8 48.9 10.4 23.0 23.3 39.3 37.9 23.7 8.8 33.2 32.5 4.2 5.7 5.5 6.6 3.3 6.8 10.1 6.1 8.0 8.0 6.7 12.8 14.9 22.4 33.4 11.4 16.0 9.9 10.1 11.3 8.0 7.3 7.2 4.6 8.5 30.0 14.5 20.2 14.6 17.6 21.2 16.0 1.9 42.5 29.5 34.9 32.8 16.0 59.9 9.0 12.1 25.0 51.6 21.3 18.3 34.5 14.0 9.2 15.4 24.2 70.3 6.7 15.0 25.5 22.4 77.4 41.9 14.5 32.6 74.9 23.2 29.0 55.4 7.6 19.6 10.6 7.3 20.3 13.3 25.9 17.7 26.7 8.7 14.9 46.2 14.5 26.3 9.2 13.5 6.8 9.7 5.0 5.3 8.8 24.8 44.3 15.5 8.5 SPG21 "ABHD21, ACP33, BM-019, GL010, MAST" ENSG00000090487 "SPG21 abhydrolase domain containing, maspardin" Q9NZD8 15 64963022-64990310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 181.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040407, HPA040436" Approved Supported Vesicles,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA040407: AB_2676965, HPA040436: AB_10796454" "unprognostic (7.47e-2)" "unprognostic (2.94e-2)" "unprognostic (5.81e-2)" "unprognostic (2.98e-1)" "unprognostic (1.64e-1)" "unprognostic (5.40e-3)" "unprognostic (7.25e-2)" "unprognostic (1.43e-1)" "unprognostic (4.19e-2)" "unprognostic (8.07e-2)" "unprognostic (4.24e-3)" "unprognostic (1.15e-1)" "unprognostic (3.96e-1)" "unprognostic (1.55e-1)" "unprognostic (3.49e-1)" "unprognostic (2.57e-1)" "unprognostic (3.19e-1)" 56.6 61.7 48.4 50.8 54.1 69.4 68.8 51.5 52.9 60.4 66.0 61.6 52.1 60.2 150.1 46.1 73.4 54.7 54.4 47.8 50.3 85.3 113.1 61.9 56.9 52.1 50.2 55.3 54.7 72.1 47.1 66.3 52.7 49.8 59.3 38.6 45.7 59.0 74.3 58.5 46.6 64.5 51.1 52.6 60.1 35.0 52.6 57.7 83.1 42.4 58.8 61.2 47.8 59.4 87.0 127.0 62.8 119.5 158.7 155.7 78.0 52.8 179.7 103.2 119.8 57.4 131.1 99.1 80.6 124.8 153.1 113.3 182.1 124.5 97.8 41.0 58.5 85.7 81.7 104.0 200.7 82.2 72.7 107.0 139.3 82.1 154.2 100.7 125.6 112.2 72.7 78.3 127.8 124.1 75.8 71.5 69.6 193.9 66.3 78.2 67.3 174.6 107.1 103.6 76.7 68.6 62.7 131.4 124.9 123.3 89.9 140.9 61.5 87.1 90.6 125.4 80.6 55.6 101.8 58.2 112.8 215.1 75.1 9.9 138.2 15.5 14.1 84.2 13.1 39.0 13.8 14.7 76.9 37.6 19.9 10.9 181.4 15.7 69.8 25.1 17.5 52.3 48.4 54.1 51.5 52.9 47.8 50.3 52.1 50.2 52.7 51.1 52.6 59.4 29.4 9.6 56.3 11.1 67.7 74.9 81.8 70.6 66.6 16.2 62.7 39.4 32.1 61.5 51.5 71.7 37.5 202.9 33.6 42.7 137.0 97.1 6.0 32.9 36.9 56.9 64.8 54.3 13.1 74.1 92.2 67.5 46.9 34.3 28.5 37.5 38.2 121.6 153.9 20.2 13.7 58.2 61.1 158.7 145.4 13.2 86.6 128.5 80.0 16.9 123.2 24.8 64.9 5.5 19.6 62.3 93.5 89.9 66.2 145.2 121.1 202.3 57.9 18.9 39.5 93.4 39.5 35.4 51.3 75.4 82.8 186.5 46.5 35.5 69.5 123.5 SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 105.4;Muller glia cells: 165.1;Pancreatic endocrine cells: 101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 127.6;TIME: 108.9;U-251 MG: 142.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "olfactory bulb: 5.7" "HPA022829, HPA028761" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA022829: AB_1857438, HPA028761: AB_10600814" "unprognostic (1.04e-1)" "unprognostic (6.30e-2)" "unprognostic (1.09e-2)" "unprognostic (8.66e-2)" "unprognostic (2.25e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (9.32e-3)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (8.99e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.14e-6)" "unprognostic (1.39e-1)" "unprognostic (4.82e-2)" "unprognostic (8.29e-2)" "unprognostic (1.10e-3)" 18.9 4.1 4.0 10.5 3.0 17.3 18.0 2.1 3.9 11.0 2.3 7.0 1.9 6.7 3.9 23.8 9.4 11.9 17.5 2.9 3.9 21.4 3.8 24.3 8.1 4.0 4.1 4.3 14.4 4.8 4.9 2.5 4.5 7.3 1.1 8.4 19.9 1.5 3.2 15.6 7.0 3.2 2.3 5.0 6.7 5.8 8.5 3.5 10.6 0.8 4.1 11.3 13.1 3.9 36.9 3.7 15.2 0.8 7.6 7.0 15.8 82.6 54.0 67.8 40.8 19.4 3.9 1.8 7.4 61.0 28.9 7.7 11.7 105.4 16.4 1.6 6.2 0.5 28.3 127.6 16.6 1.3 2.9 13.6 2.1 105.9 41.3 28.8 66.0 3.7 17.3 0.2 13.5 46.6 3.5 0.6 0.9 8.2 29.7 2.5 4.1 2.8 3.7 0.5 2.0 3.6 8.3 0.9 74.4 9.1 3.0 5.1 108.9 105.8 20.8 82.3 142.1 1.7 0.4 1.6 80.5 6.5 16.1 1.5 1.9 0.0 0.7 0.9 0.2 0.0 0.1 0.2 0.5 0.1 0.0 0.1 0.2 0.0 0.2 4.8 0.0 0.8 4.0 3.0 2.1 3.9 2.9 3.9 4.0 4.1 4.5 2.3 8.5 3.9 22.0 0.0 0.0 1.0 2.8 12.6 57.0 18.6 2.8 1.5 31.1 29.1 5.3 47.1 6.6 1.8 0.0 1.2 9.1 1.0 0.0 105.4 0.2 15.3 13.5 51.2 0.0 22.3 0.5 12.7 16.9 27.5 3.1 60.7 7.0 0.4 4.2 0.2 30.1 33.7 1.6 2.4 6.1 8.9 45.4 1.4 3.7 39.9 12.4 1.0 61.5 165.1 3.1 0.0 0.1 101.8 1.2 19.9 3.5 68.9 0.8 2.5 2.0 3.9 0.0 17.3 54.3 0.0 9.5 6.7 10.7 1.4 4.2 0.8 0.4 27.0 SPOCK1 "SPOCK, testican-1, TIC1" ENSG00000152377 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1" Q08629 5 136975298-137598379 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 172.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 252.8;Inhibitory neurons: 349.9;Muller glia cells: 243.8;Oligodendrocyte precursor cells: 273.4;Oligodendrocytes: 913.1;Peritubular cells: 150.1" "Cancer enriched" "Detected in all" 7 "prostate cancer: 83.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 573.1;hTERT-RPE1: 1112.8;HUVEC TERT2: 594.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007450, HPA026770" Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA007450: AB_10603116, HPA026770: " "unprognostic (1.05e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (1.58e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.83e-3)" "prognostic unfavorable (9.08e-4)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.72e-4)" "unprognostic (9.09e-3)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.77e-5)" "prognostic unfavorable (9.40e-4)" "unprognostic (1.26e-1)" "unprognostic (2.21e-1)" "unprognostic (1.90e-2)" 29.7 41.4 67.9 4.1 116.3 0.3 19.0 129.2 99.5 25.6 9.9 24.9 1.2 44.2 34.3 6.1 18.6 18.6 54.2 100.5 50.9 24.3 0.2 2.9 0.6 80.7 84.5 4.8 5.5 13.7 9.9 9.3 89.8 65.6 3.2 48.7 7.6 25.5 17.5 9.3 4.6 30.7 78.4 8.5 9.1 21.7 102.6 7.5 9.4 7.1 0.4 11.4 21.7 172.9 4.6 0.9 299.4 0.4 573.1 116.0 0.4 100.6 90.0 207.7 115.9 0.0 0.6 0.4 0.2 206.7 53.3 4.4 1.4 70.3 65.3 17.8 0.6 0.2 16.7 0.0 4.0 0.0 0.4 203.8 28.5 128.6 23.2 1112.8 594.4 0.2 0.0 0.4 60.5 0.5 0.0 0.2 19.1 0.0 28.4 0.0 0.2 0.0 140.3 9.4 3.7 14.4 49.9 0.8 0.1 35.6 0.4 1.2 98.9 294.0 10.6 102.1 28.5 0.1 0.1 0.1 159.4 4.4 136.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 67.9 116.3 129.2 99.5 100.5 50.9 80.7 84.5 89.8 78.4 102.6 172.9 2.0 0.0 0.0 91.7 0.0 1.8 1.6 5.8 0.0 9.7 0.4 0.4 58.8 1.5 0.4 22.0 2.1 0.4 0.0 0.2 1.9 0.6 12.0 4.2 37.9 8.4 35.0 0.0 252.8 1.4 0.3 58.8 0.0 2.9 0.0 0.1 1.1 0.0 0.9 8.4 349.9 0.1 16.2 1.2 3.0 9.5 17.4 1.6 7.2 17.8 2.3 243.8 0.0 273.4 913.1 2.0 0.1 150.1 0.1 40.9 0.0 3.1 0.9 7.3 13.1 11.6 16.4 7.4 7.1 0.7 1.4 0.1 0.4 0.0 0.3 3.2 SPOCK3 testican-3 ENSG00000196104 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3" Q9BQ16 4 166733384-167234796 "Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 143.9;parathyroid gland: 175.0;prostate: 73.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 1010.6;Oligodendrocyte precursor cells: 399.1;Oligodendrocytes: 1851.1" "Cancer enhanced" "Detected in many" "prostate cancer: 7.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.2;myeloid DC: 1.8" "Group enriched" "Detected in many" 12 "dendritic cells: 1.8;monocytes: 1.2" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.2;hTERT-RPE1: 6.5;PC-3: 2.7;RH-30: 7.1;SCLC-21H: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.54e-2)" "unprognostic (8.69e-2)" "unprognostic (2.90e-3)" "unprognostic (1.20e-1)" "unprognostic (4.09e-4)" "unprognostic (3.75e-1)" "unprognostic (1.97e-2)" "unprognostic (1.44e-1)" "unprognostic (1.88e-1)" "unprognostic (3.94e-4)" "unprognostic (8.92e-2)" "unprognostic (4.18e-3)" "unprognostic (2.62e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-3)" "unprognostic (1.64e-1)" 0.3 24.7 51.4 0.6 87.2 0.1 0.3 73.0 97.3 0.9 18.7 0.9 0.8 2.9 18.8 0.2 1.1 0.3 0.3 48.4 63.8 0.2 0.4 0.4 0.5 83.2 64.9 17.4 0.7 175.0 0.3 0.0 79.4 73.9 0.5 14.3 0.3 34.9 0.2 0.0 1.3 2.8 72.8 0.4 0.7 0.5 68.4 0.3 0.2 24.0 0.3 1.7 0.2 143.9 0.0 1.6 0.2 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.4 0.1 0.2 0.0 1.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 6.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 2.7 0.0 7.1 0.4 0.0 1.1 2.8 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.5 51.4 87.2 73.0 97.3 48.4 63.8 83.2 64.9 79.4 72.8 68.4 143.9 0.0 0.0 0.0 12.7 0.1 0.0 1.5 8.1 0.0 43.7 0.0 0.0 1.6 0.0 10.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 15.0 0.0 0.2 1.6 0.0 1.3 106.7 0.0 0.1 15.7 2.0 0.0 1.3 3.2 0.0 0.0 0.1 15.2 1010.6 0.0 6.1 0.0 0.0 2.9 0.9 0.5 0.0 98.4 0.2 1.3 0.0 399.1 1851.1 0.1 0.0 0.4 0.0 3.3 0.0 0.1 6.7 6.3 0.0 0.0 2.5 0.5 0.7 0.0 0.0 0.1 0.0 55.4 0.0 0.8 SPR SDR38C1 ENSG00000116096 "Sepiapterin reductase" P35270 2 72887382-72892158 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 85.3;Exocrine glandular cells: 81.1;Proximal tubular cells: 91.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 8.3;intermediate monocyte: 2.4;myeloid DC: 8.9" "Group enriched" "Detected in many" 11 "dendritic cells: 8.9;monocytes: 8.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039505 Uncertain Supported Nucleoplasm,Cytosol NA NA 180000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "HPA039505: AB_10795466" "unprognostic (4.09e-1)" "unprognostic (1.22e-1)" "unprognostic (7.72e-3)" "unprognostic (1.97e-1)" "unprognostic (2.46e-2)" "unprognostic (1.06e-2)" "unprognostic (1.36e-1)" "unprognostic (1.47e-1)" "unprognostic (1.12e-1)" "unprognostic (9.79e-2)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (7.50e-3)" "unprognostic (2.87e-1)" "unprognostic (1.43e-3)" "unprognostic (1.95e-1)" 25.9 50.8 26.0 7.6 27.2 0.6 20.0 27.2 61.4 14.5 39.6 36.4 23.4 13.4 36.9 19.7 26.3 11.9 44.4 26.8 30.0 44.2 99.8 15.9 3.2 27.9 31.5 12.2 63.5 38.4 10.9 6.8 29.8 26.2 32.5 3.1 31.2 16.7 43.9 9.1 22.0 11.5 27.9 9.6 42.1 7.3 28.5 2.4 20.5 25.4 5.1 25.2 13.7 28.0 47.5 130.9 0.6 20.0 51.2 18.5 31.8 21.4 31.8 16.0 15.0 84.0 48.0 34.5 25.4 26.1 80.6 43.9 58.1 35.1 13.3 10.0 43.7 51.7 30.8 87.4 19.1 8.2 13.6 16.7 38.7 17.6 19.7 32.7 42.6 25.4 54.0 6.8 21.4 100.5 3.3 31.1 10.9 139.9 118.7 0.0 82.8 20.3 85.8 73.4 8.0 14.6 39.6 89.7 31.0 16.9 40.4 9.9 52.8 17.4 42.2 30.5 38.7 7.2 16.9 2.3 25.0 17.6 31.0 0.0 8.3 0.7 0.3 2.4 0.3 0.0 0.1 0.1 8.9 0.0 0.1 0.3 0.0 0.0 0.9 0.9 0.0 2.4 26.0 27.2 27.2 61.4 26.8 30.0 27.9 31.5 29.8 27.9 28.5 28.0 13.8 12.8 7.3 0.3 1.1 8.4 23.0 14.8 20.5 0.7 22.2 16.5 46.2 38.6 10.8 42.3 0.0 18.1 0.4 85.3 21.5 56.9 0.3 12.5 4.2 16.7 11.4 6.6 0.7 81.1 10.6 13.9 26.0 6.7 4.5 8.4 17.2 62.9 42.1 1.7 0.4 39.6 12.2 6.0 7.4 1.5 9.3 9.7 14.2 1.9 20.8 13.8 0.0 0.0 0.3 43.3 50.4 5.7 1.4 33.9 71.0 91.6 11.2 0.7 6.6 8.3 8.6 0.4 10.2 17.8 6.5 4.4 1.9 8.7 57.8 15.6 SPTLC1 "hLCB1, HSAN1, HSN1, LCB1, SPTI" ENSG00000090054 "Serine palmitoyltransferase long chain base subunit 1" O15269 9 92000087-92115413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010860, CAB018747, HPA063907" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "CAB018747: AB_2195864, HPA010860: AB_1080086, HPA063907: AB_2685148" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (3.51e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.06e-1)" "unprognostic (3.55e-3)" "unprognostic (8.37e-2)" "prognostic favorable (1.36e-6)" "unprognostic (1.13e-1)" "unprognostic (2.41e-2)" "unprognostic (4.28e-1)" "unprognostic (1.49e-1)" 35.6 32.6 24.0 27.3 27.0 23.3 44.1 26.0 34.2 43.1 28.6 42.3 34.7 40.4 41.3 54.3 36.7 34.1 21.5 24.3 26.6 42.8 23.4 33.6 25.7 27.8 27.5 43.8 26.5 48.0 17.3 42.4 28.0 32.9 44.1 19.8 31.3 28.1 14.2 41.3 37.9 31.4 27.9 26.3 37.1 26.5 25.6 25.9 53.0 18.6 34.4 37.2 34.7 31.6 73.0 48.8 46.8 41.6 120.0 92.0 78.4 74.7 94.2 65.3 66.3 31.5 150.7 38.6 45.1 93.9 78.3 198.4 49.7 68.1 73.0 39.8 36.1 36.7 32.7 51.7 80.5 65.5 49.9 82.6 92.6 68.0 74.8 72.3 62.5 43.5 83.8 46.6 91.1 69.6 34.7 47.6 67.5 97.4 57.9 39.4 58.7 33.3 84.1 37.9 35.0 37.2 104.4 81.1 61.3 62.4 39.2 54.2 72.3 58.8 48.0 73.9 56.8 33.2 44.4 23.9 74.2 39.3 79.4 32.4 33.1 20.2 16.7 36.1 17.0 15.4 18.0 17.4 30.6 15.5 21.4 16.6 33.3 18.5 34.2 18.4 25.7 25.5 24.0 27.0 26.0 34.2 24.3 26.6 27.8 27.5 28.0 27.9 25.6 31.6 40.7 38.5 38.3 27.7 22.1 10.6 13.6 14.5 26.2 6.9 33.2 20.6 4.1 4.3 25.9 36.8 14.6 12.7 24.4 8.0 9.8 53.4 94.8 34.7 42.5 23.1 2.4 7.2 35.3 56.4 15.6 32.3 13.7 47.4 24.6 26.9 6.1 4.3 11.0 6.7 32.5 7.2 12.2 5.7 10.3 26.1 6.2 24.6 12.4 20.6 22.0 13.7 7.2 36.7 52.1 60.8 7.1 6.0 26.2 9.8 11.7 28.5 28.0 8.7 13.1 12.1 23.5 35.3 25.9 27.6 9.1 21.8 21.9 33.2 6.9 14.5 SPTSSA "C14orf147, ssSPTa" ENSG00000165389 "Serine palmitoyltransferase small subunit A" Q969W0 14 34432788-34462240 "Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 405.2;Melanocytes: 435.8;Suprabasal keratinocytes: 443.8;Syncytiotrophoblasts: 512.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 180.0" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (6.24e-3)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (4.00e-1)" "unprognostic (3.19e-2)" "unprognostic (2.44e-2)" "unprognostic (6.64e-2)" "unprognostic (1.19e-1)" "unprognostic (1.24e-2)" "unprognostic (2.40e-1)" "unprognostic (3.25e-1)" "unprognostic (5.86e-2)" 25.1 71.1 13.5 21.1 13.6 5.7 39.3 13.8 17.9 21.0 13.8 38.4 20.8 16.9 25.6 25.3 21.4 27.1 16.2 12.6 15.8 23.5 46.9 33.6 12.2 18.6 15.4 20.1 13.9 18.2 13.3 28.8 17.0 22.5 36.0 15.3 34.2 24.7 24.4 22.2 21.9 27.3 15.1 13.2 20.5 7.1 14.6 8.5 19.8 19.0 13.0 30.6 26.0 16.2 67.4 38.3 37.6 14.0 61.6 42.8 44.4 44.1 27.2 34.1 41.0 31.3 39.4 56.0 38.8 25.1 25.0 28.2 34.1 37.5 53.7 29.7 21.1 35.2 74.0 153.7 48.5 46.5 19.9 39.8 58.9 25.2 40.8 26.4 40.9 15.7 25.6 58.3 30.4 71.0 19.2 47.0 28.9 32.2 47.4 24.8 180.0 41.2 42.8 29.5 24.6 32.6 100.9 87.7 71.3 29.4 39.9 50.0 43.4 26.8 17.5 27.7 33.4 48.1 34.1 41.0 18.0 40.8 30.4 21.5 36.9 4.9 5.4 29.9 5.3 8.3 4.9 5.3 19.6 7.1 5.1 6.2 2.0 20.8 25.5 7.0 5.3 21.5 13.5 13.6 13.8 17.9 12.6 15.8 18.6 15.4 17.0 15.1 14.6 16.2 51.0 144.2 123.5 14.4 33.1 405.2 166.6 192.0 217.9 40.9 165.5 63.1 33.2 70.1 108.9 88.3 10.4 265.8 31.5 189.6 154.6 257.7 1.3 62.2 165.4 65.5 49.7 66.1 11.2 96.8 126.2 100.9 34.7 100.6 32.4 24.1 50.3 79.1 78.3 40.4 13.5 74.9 120.1 67.1 127.6 2.7 45.7 56.5 435.8 15.0 71.0 43.8 18.6 14.1 30.5 71.0 102.4 60.2 70.9 118.3 75.0 96.7 30.8 31.2 46.0 78.5 98.6 1.9 6.1 167.7 443.8 512.4 33.8 82.9 107.6 153.5 STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Cell type enriched" "Detected in many" 4 "Hepatic stellate cells: 745.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Group enriched" "Detected in some" 46 "HUVEC TERT2: 103.1;NB-4: 146.9;TIME: 128.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" 194.2 160.4 41.0 50.4 42.9 13.8 84.5 41.4 58.3 54.4 62.8 87.7 29.6 45.3 8.5 29.2 79.3 25.8 74.6 41.9 44.4 85.6 102.1 104.7 12.9 50.0 48.4 32.2 32.2 5.0 52.0 55.4 53.7 57.6 31.0 0.6 45.7 16.0 25.9 24.0 95.1 33.8 43.0 439.5 53.2 21.0 65.3 6.8 55.1 4.6 8.2 105.7 48.6 47.8 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.2 0.2 0.6 0.0 0.0 1.8 0.1 0.0 0.1 0.0 103.1 0.1 0.3 0.1 0.0 0.0 0.0 146.9 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.0 0.0 128.8 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 9.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 41.0 42.9 41.4 58.3 41.9 44.4 50.0 48.4 53.7 43.0 65.3 47.8 31.3 0.0 3.8 0.0 5.5 6.0 0.6 0.0 1.8 1.0 1.5 2.7 2.4 11.5 0.0 3.7 0.0 1.7 1.9 0.0 0.0 0.0 0.5 0.4 0.5 43.0 1.2 21.5 0.3 0.0 2.0 3.3 0.5 0.3 18.3 0.0 745.0 19.7 130.7 0.0 0.3 0.0 0.0 185.4 30.3 2.9 4.4 147.0 12.4 30.0 21.9 0.5 2.1 0.5 0.1 0.0 0.0 20.3 2.0 0.2 0.0 0.8 0.0 0.1 19.7 2.0 1.4 0.9 2.2 1.5 4.8 2.2 2.3 0.5 0.0 0.2 STEAP3 "dudlin-2, STMP3, TSAP6" ENSG00000115107 "STEAP3 metalloreductase" Q658P3 2 119223831-119265652 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 189.5;parathyroid gland: 78.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.3;Exocrine glandular cells: 36.2;Hepatocytes: 91.6;Respiratory ciliated cells: 36.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.4;intermediate monocyte: 2.7;myeloid DC: 4.1;NK-cell: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 4.1;monocytes: 2.7;NK-cells: 1.3" "Cell line enhanced" "Detected in many" "U-87 MG: 149.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA050510 Approved Approved Nucleoli,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Nucleoli "HPA050510: AB_2681151" "unprognostic (6.51e-2)" "unprognostic (6.48e-2)" "unprognostic (4.89e-2)" "unprognostic (3.45e-2)" "unprognostic (1.94e-3)" "unprognostic (9.07e-2)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (9.75e-2)" "unprognostic (1.58e-3)" "unprognostic (5.08e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.82e-1)" "unprognostic (4.45e-1)" "unprognostic (9.37e-2)" "unprognostic (6.82e-2)" 9.1 6.3 4.3 3.9 3.7 16.9 14.5 7.1 4.6 16.7 10.6 9.5 22.1 3.6 5.3 15.8 7.7 2.3 9.5 7.0 7.5 6.9 189.5 9.1 0.9 14.4 9.4 4.4 27.1 78.9 13.8 11.3 12.8 11.8 6.9 0.7 34.3 7.5 29.9 9.0 10.9 3.1 7.6 1.8 22.5 1.9 7.2 2.2 5.4 12.5 3.1 7.0 7.2 12.7 21.8 25.6 0.0 8.7 12.1 112.9 22.1 6.8 7.4 13.1 11.8 19.5 29.0 0.1 49.9 38.5 94.1 35.9 11.1 22.4 14.9 0.1 35.9 42.1 22.2 38.8 30.0 10.5 7.7 67.3 38.7 78.0 27.7 89.8 11.4 0.0 20.9 4.2 37.6 20.6 0.1 6.2 34.2 33.3 52.7 0.2 14.7 18.5 16.2 54.1 41.9 7.7 18.8 64.1 4.9 4.9 12.7 13.7 49.6 81.2 46.8 17.4 37.4 0.1 0.1 0.2 149.1 26.2 17.2 0.0 2.4 0.4 0.1 2.7 0.0 0.4 0.0 0.0 4.1 0.1 0.0 0.0 0.0 1.3 0.4 0.2 0.0 1.0 4.3 3.7 7.1 4.6 7.0 7.5 14.4 9.4 12.8 7.6 7.2 12.7 9.1 0.0 7.9 2.3 1.0 2.0 7.4 11.9 8.0 0.6 15.5 10.7 6.2 2.8 16.2 0.0 0.0 33.3 0.2 12.2 0.0 8.1 0.2 8.1 1.9 6.2 1.8 29.5 1.3 36.2 4.1 3.6 23.4 5.7 3.8 3.5 1.4 91.6 10.9 0.0 1.0 6.0 8.2 5.9 3.8 0.7 1.8 6.1 0.0 1.9 1.4 0.1 0.0 0.5 0.0 20.8 7.7 7.5 0.1 8.3 11.8 1.5 36.1 0.1 6.6 4.1 3.3 0.6 0.2 19.5 1.4 23.7 0.4 13.1 11.6 8.9 STK32C "MGC23665, PKE, YANK3" ENSG00000165752 "Serine/threonine kinase 32C" Q86UX6 10 132207492-132331847 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 54.1" "Group enriched" "Detected in many" 4 "Early spermatids: 278.9;Late spermatids: 83.3;Spermatocytes: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 55.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017894 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "HPA017894: AB_1857591" "unprognostic (2.11e-1)" "unprognostic (8.40e-2)" "unprognostic (4.80e-3)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.65e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (1.68e-6)" "unprognostic (2.03e-1)" "unprognostic (7.79e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (5.31e-6)" "unprognostic (8.65e-2)" "unprognostic (3.20e-1)" "unprognostic (5.05e-2)" "unprognostic (1.36e-1)" 11.0 12.5 31.4 7.1 39.6 7.6 8.9 17.8 37.5 8.1 13.5 9.1 5.2 6.9 14.8 5.4 9.4 6.5 7.4 31.3 23.2 15.6 5.0 8.8 10.0 24.6 26.1 6.7 7.4 6.0 12.3 4.9 20.5 6.6 4.7 7.9 5.7 5.2 13.7 7.6 6.8 5.0 23.4 15.1 6.2 54.1 30.9 10.8 6.4 9.1 6.4 8.3 6.5 25.9 69.4 43.5 13.3 33.5 18.4 23.3 2.7 14.1 10.7 17.4 22.2 10.0 46.0 14.8 10.3 16.4 22.0 14.9 18.6 5.5 16.9 8.9 31.1 8.9 46.1 47.1 22.9 7.9 31.1 17.6 20.8 15.7 17.3 22.0 15.6 25.1 15.4 10.2 19.0 21.1 10.4 30.4 8.8 12.6 31.4 12.2 8.2 4.9 23.3 11.7 34.6 27.3 10.2 9.3 20.9 7.9 10.5 19.2 10.6 13.6 14.2 18.2 11.3 19.1 3.8 38.7 31.4 7.4 7.1 55.3 17.9 16.5 5.8 19.6 7.3 6.2 4.7 6.6 25.1 10.2 5.8 4.5 2.4 6.1 17.3 14.5 9.2 7.0 31.4 39.6 17.8 37.5 31.3 23.2 24.6 26.1 20.5 23.4 30.9 25.9 6.6 0.0 7.2 13.4 7.3 5.2 6.8 5.7 4.6 8.4 10.3 11.0 3.7 2.8 6.1 12.9 12.5 3.4 9.3 3.2 19.6 5.4 278.9 25.9 8.2 8.2 19.2 15.8 22.9 8.7 2.3 7.2 6.6 11.8 15.8 6.0 13.6 5.5 14.6 37.0 13.9 7.4 12.2 24.3 28.5 83.3 9.0 14.8 12.4 7.5 14.0 11.0 6.2 9.5 10.0 6.0 5.1 6.8 4.8 11.4 3.8 13.2 13.7 14.6 6.6 10.5 5.6 89.8 20.0 5.9 5.1 1.5 9.3 10.1 7.6 7.3 SULF2 "HSULF-2, KIAA1247, SULF-2" ENSG00000196562 "Sulfatase 2" Q8IWU5 20 47656348-47786616 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 205.8;Oligodendrocyte precursor cells: 247.8;Theca cells: 265.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "basophil: 27.2;classical monocyte: 19.6;intermediate monocyte: 17.2;myeloid DC: 21.3;neutrophil: 31.5;non-classical monocyte: 9.0;plasmacytoid DC: 27.1" "Group enriched" "Detected in many" 84 "dendritic cells: 27.1;granulocytes: 31.5;monocytes: 19.6" "Cell line enhanced" "Detected in many" "EFO-21: 338.0;HaCaT: 230.1;HBEC3-KT: 259.4;hTCEpi: 815.1;MCF7: 695.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002325 Approved "Intracellular and membrane" NA NA 340000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "HPA002325: AB_1080126" "unprognostic (4.06e-2)" "prognostic unfavorable (6.43e-5)" "unprognostic (4.39e-1)" "unprognostic (8.99e-2)" "unprognostic (2.65e-1)" "unprognostic (9.08e-2)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" "unprognostic (1.81e-2)" "unprognostic (3.04e-2)" "unprognostic (1.53e-3)" "unprognostic (1.85e-1)" "prognostic unfavorable (4.02e-4)" "unprognostic (7.83e-2)" "unprognostic (1.14e-1)" "unprognostic (1.09e-1)" "unprognostic (7.14e-3)" 57.5 12.4 25.8 42.7 30.3 11.5 43.5 21.0 30.7 113.3 20.5 48.0 29.4 152.6 9.8 77.5 73.5 64.3 35.6 45.8 41.4 57.2 38.7 16.5 27.8 56.8 51.1 139.3 9.8 7.1 40.4 26.3 57.1 23.3 43.9 13.6 34.0 22.4 14.7 32.7 26.9 86.5 22.3 15.1 20.6 21.3 30.1 18.2 42.7 22.5 25.1 36.6 62.6 22.6 0.5 20.6 93.4 0.1 19.2 2.3 8.5 16.3 0.0 1.7 2.9 36.7 48.7 3.7 338.0 17.0 5.5 230.1 27.2 259.4 0.7 0.4 20.0 0.0 24.2 82.7 17.4 0.1 4.9 104.1 815.1 1.7 11.2 0.2 18.4 0.0 0.0 151.5 1.9 695.2 0.0 1.4 18.8 0.0 209.0 0.2 0.2 39.8 198.6 1.1 8.2 2.1 32.9 0.3 0.1 122.1 1.3 2.6 17.8 0.0 2.1 0.2 22.5 5.4 1.7 1.6 0.4 0.1 2.8 27.2 19.6 2.2 0.0 17.2 0.2 0.3 0.0 0.1 21.3 0.2 0.0 0.0 31.5 0.1 9.0 27.1 0.0 6.2 25.8 30.3 21.0 30.7 45.8 41.4 56.8 51.1 57.1 22.3 30.1 22.6 62.7 9.6 7.2 2.0 21.9 10.5 7.6 25.4 18.8 8.5 14.0 8.3 8.6 20.0 9.0 16.5 0.0 12.0 34.9 38.4 0.0 5.3 2.7 19.7 205.8 59.2 27.4 7.8 10.3 2.2 10.1 37.0 10.2 30.6 1.3 28.1 62.2 19.0 5.2 35.3 10.8 7.6 16.2 20.6 46.2 6.7 28.9 44.4 10.6 12.2 85.8 8.8 6.2 247.8 1.1 4.9 62.0 76.3 6.2 9.9 3.5 14.1 2.7 6.2 0.0 4.1 13.7 1.2 3.5 24.7 8.4 16.4 11.2 265.0 25.8 12.3 SULT1A3 "STM, TL-PST" ENSG00000261052 "Sulfotransferase family 1A member 3" P0DMM9 16 30199228-30204310 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 237.2" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 129.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 61.3;intermediate monocyte: 53.2;myeloid DC: 33.7;non-classical monocyte: 25.0" "Group enriched" "Detected in all" 11 "dendritic cells: 33.7;monocytes: 61.3" "Cell line enhanced" "Detected in all" "CAPAN-2: 166.9;Hep G2: 303.6;Karpas-707: 239.4" "HPA049500, HPA051051" Supported NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA049500: AB_2680796, HPA051051: AB_2681327" "unprognostic (2.61e-1)" "unprognostic (1.72e-3)" "unprognostic (1.98e-3)" "unprognostic (4.98e-2)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (7.27e-2)" "unprognostic (2.09e-2)" "unprognostic (2.99e-2)" "unprognostic (2.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (9.18e-8)" "unprognostic (2.34e-2)" "unprognostic (2.51e-1)" "unprognostic (1.66e-1)" "unprognostic (9.48e-5)" 15.7 13.7 53.3 21.9 54.0 36.8 15.7 56.3 72.9 15.4 54.3 57.3 237.2 16.8 18.0 14.3 18.0 14.8 11.0 54.0 53.9 34.6 34.5 26.6 30.3 53.8 53.0 10.8 15.9 17.5 23.8 22.4 54.3 20.1 46.4 23.2 25.8 17.8 11.0 25.7 146.6 24.5 52.0 31.8 22.2 9.6 54.3 16.3 20.2 18.9 29.3 13.5 10.5 55.9 32.6 48.8 30.6 21.3 28.4 19.8 46.0 15.8 16.9 16.7 18.9 21.1 166.9 16.9 150.0 16.0 10.9 45.5 38.8 14.0 16.7 19.9 30.6 93.2 61.2 303.6 11.1 14.2 34.9 21.9 20.9 25.4 5.9 34.2 30.6 21.9 19.0 239.4 12.0 55.4 9.6 62.3 19.1 76.2 20.9 38.6 14.8 32.2 29.4 22.0 15.3 24.7 4.8 43.0 7.8 11.4 23.8 22.1 38.3 34.0 17.4 29.4 11.7 28.8 78.1 8.7 17.4 31.7 20.5 1.9 61.3 0.3 4.3 53.2 0.9 3.4 1.1 1.5 33.7 1.7 0.8 0.7 1.6 1.4 25.0 0.5 0.9 20.4 53.3 54.0 56.3 72.9 54.0 53.9 53.8 53.0 54.3 52.0 54.3 55.9 3.3 12.8 12.0 0.0 4.2 2.0 2.2 1.2 0.6 5.3 2.4 1.3 1.8 4.3 7.6 0.0 8.4 5.3 2.8 13.9 0.0 3.3 1.3 0.9 0.9 5.8 1.2 6.1 0.0 4.0 2.3 4.4 2.6 1.3 1.3 1.7 3.9 2.8 1.5 1.7 0.0 13.4 2.0 5.0 3.7 0.5 0.9 2.6 1.8 0.0 4.9 2.6 4.1 0.0 0.0 6.3 25.3 1.9 1.4 4.3 129.1 0.5 2.3 6.7 0.0 1.7 1.7 0.8 0.3 0.9 2.7 3.0 3.8 1.2 26.8 2.1 SUMF1 "FGE, UNQ3037" ENSG00000144455 "Sulfatase modifying factor 1" Q8NBK3 3 3700814-4467273 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 116.4;hTERT-RPE1: 117.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038025 Uncertain "Intracellular and membrane" NA NA 2800000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA038025: AB_10675624" "unprognostic (5.02e-2)" "unprognostic (2.30e-1)" "unprognostic (1.08e-1)" "unprognostic (8.99e-3)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (8.34e-3)" "unprognostic (3.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (2.65e-2)" "unprognostic (2.28e-1)" "prognostic favorable (4.79e-7)" "unprognostic (5.12e-2)" "unprognostic (2.58e-1)" "unprognostic (1.45e-1)" "unprognostic (7.86e-2)" 20.7 19.5 10.4 13.1 12.0 10.2 29.2 10.9 12.2 21.3 15.6 23.9 13.3 15.8 26.8 28.7 25.6 19.7 12.5 10.2 12.2 39.3 27.4 23.0 12.6 12.2 11.7 17.4 18.9 46.8 14.5 18.8 11.4 22.1 29.6 3.4 22.8 17.7 4.3 20.3 14.1 20.5 11.4 16.8 23.8 5.1 13.1 10.6 28.4 7.6 13.4 20.0 18.5 13.1 25.0 20.6 11.4 6.3 116.4 61.3 21.9 34.4 53.9 16.2 18.2 9.6 78.9 3.7 20.3 63.0 24.3 13.3 5.0 39.0 25.2 12.0 10.1 5.4 18.9 26.2 30.0 6.1 14.4 56.6 43.2 18.2 5.3 117.9 44.8 8.9 9.1 8.4 45.8 40.2 3.4 9.1 12.0 22.8 23.4 6.3 17.0 16.0 86.6 28.0 2.2 12.6 24.6 56.8 20.4 19.5 75.7 15.6 41.4 32.5 4.2 25.3 21.0 10.4 22.8 1.7 63.2 13.5 24.7 66.1 100.5 35.6 38.9 81.8 35.2 26.6 31.2 32.9 86.6 30.7 39.4 32.0 36.2 42.0 78.2 45.9 16.9 90.2 10.4 12.0 10.9 12.2 10.2 12.2 12.2 11.7 11.4 11.4 13.1 13.1 12.8 19.2 20.1 36.9 13.8 12.7 18.8 32.9 21.1 5.6 29.5 23.2 5.5 18.6 16.7 38.6 6.2 29.8 9.7 16.5 11.7 39.3 26.1 14.2 14.1 13.7 8.4 11.1 53.2 19.1 23.3 25.8 21.4 21.9 17.1 10.4 17.5 18.7 28.2 3.3 57.0 19.7 4.1 37.1 12.0 10.7 16.4 24.3 19.6 62.8 43.9 6.8 11.3 56.8 85.5 14.0 16.4 17.3 11.5 13.7 10.5 23.8 19.4 6.2 6.6 21.2 16.5 4.8 5.1 25.9 11.8 24.4 11.6 11.1 25.6 18.3 TBC1D2 "Armus, PARIS1, TBC1D2A" ENSG00000095383 "TBC1 domain family member 2" Q9BYX2 9 98199011-98255649 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Oligodendrocytes: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 77.0;HaCaT: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030871, HPA076521" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA030871: AB_10670046, HPA076521: " "unprognostic (2.32e-2)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (2.77e-4)" "unprognostic (1.86e-1)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (9.21e-3)" "unprognostic (6.40e-3)" "unprognostic (2.30e-1)" "unprognostic (6.07e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.30e-2)" "unprognostic (4.30e-1)" 8.8 5.3 11.1 5.7 16.0 13.1 7.8 12.3 26.0 10.8 8.5 8.6 12.6 4.4 1.5 37.4 5.5 4.0 3.7 10.6 12.9 6.4 19.8 32.0 3.8 14.9 14.9 2.9 3.0 3.5 4.4 7.2 16.4 12.0 4.4 3.4 14.7 6.1 4.3 24.3 10.1 2.8 11.4 9.4 7.0 3.4 23.3 3.0 8.1 1.4 4.9 11.7 17.3 23.9 77.0 10.8 0.5 2.5 8.2 15.9 24.3 33.2 18.4 23.8 19.6 6.9 32.8 1.3 24.7 19.6 5.2 98.1 0.7 36.8 8.3 2.6 1.4 0.7 38.0 5.4 37.6 1.7 2.9 21.7 59.8 23.6 58.7 41.5 8.6 2.1 2.4 1.0 19.0 9.9 0.4 4.6 1.6 7.4 6.2 1.2 4.8 0.2 36.0 46.7 0.9 1.4 11.3 24.4 3.4 1.7 8.1 2.6 51.7 28.8 8.6 4.8 13.6 1.6 1.5 0.6 29.0 2.9 3.2 2.1 27.5 8.4 2.5 15.3 1.8 1.2 3.8 2.2 10.0 0.8 1.6 1.9 11.9 1.2 12.3 1.3 5.5 10.8 11.1 16.0 12.3 26.0 10.6 12.9 14.9 14.9 16.4 11.4 23.3 23.9 2.9 57.7 12.5 5.2 2.4 8.3 18.5 30.4 21.6 3.3 2.7 5.6 0.7 4.3 23.3 3.7 0.0 21.5 0.9 16.2 3.9 3.3 1.8 4.6 3.7 5.0 7.7 0.4 4.6 3.2 10.9 2.4 6.1 10.3 0.0 0.6 1.1 6.1 32.0 1.7 5.4 12.6 18.3 16.2 1.8 1.2 1.8 18.3 3.6 4.7 7.5 4.4 3.1 12.1 64.9 14.4 10.7 0.7 1.7 9.2 16.4 3.2 10.8 2.4 0.0 1.8 3.4 2.1 3.0 29.8 10.9 17.4 2.4 0.7 5.7 17.1 TDRD9 "C14orf75, DKFZp434N0820, FLJ36164, NET54" ENSG00000156414 "Tudor domain containing 9" Q8NDG6 14 103928456-104052667 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "parathyroid gland: 30.6;testis: 40.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 43.2;Spermatocytes: 63.2;Spermatogonia: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 1.6" "Lineage enriched" "Detected in single" 6 "monocytes: 1.6" "Cell line enhanced" "Detected in some" "HDLM-2: 24.4;HeLa: 21.5;HMC-1: 94.2;RPTEC TERT1: 25.5;SK-MEL-30: 13.3" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (3.71e-1)" "unprognostic (3.02e-1)" "unprognostic (1.59e-1)" "unprognostic (1.89e-1)" "unprognostic (1.91e-1)" "unprognostic (1.55e-1)" "unprognostic (2.74e-1)" "unprognostic (3.74e-1)" "unprognostic (1.55e-1)" "unprognostic (1.61e-1)" "unprognostic (2.13e-4)" "unprognostic (1.60e-2)" "unprognostic (4.57e-3)" "unprognostic (8.97e-2)" "unprognostic (3.34e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.41e-2)" 0.4 0.5 0.9 0.6 0.8 1.7 0.5 1.3 0.9 0.4 1.2 0.3 0.1 0.4 0.4 0.2 0.9 0.9 0.6 0.8 0.8 2.1 0.3 1.0 0.5 1.7 1.0 0.2 0.5 30.6 1.0 0.5 2.0 0.3 0.2 3.5 0.3 0.5 0.1 0.1 0.3 0.5 1.1 3.0 0.8 40.7 1.1 0.3 5.4 0.5 0.5 0.4 0.2 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.4 0.0 0.0 21.5 0.0 0.0 0.0 94.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 25.5 0.0 8.7 0.0 0.0 0.6 13.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.8 1.3 0.9 0.8 0.8 1.7 1.0 2.0 1.1 1.1 1.3 0.9 6.4 2.0 2.3 0.0 0.0 0.1 0.1 0.0 4.3 1.0 0.4 12.4 0.0 0.7 0.0 4.2 0.0 0.5 0.0 1.9 0.6 13.1 43.2 1.5 0.9 0.0 1.3 9.1 0.0 0.0 0.7 0.0 3.7 0.0 0.3 0.4 0.1 1.9 6.7 4.6 0.0 2.0 1.8 0.0 7.3 0.9 1.5 0.0 2.8 2.9 0.6 0.0 1.0 4.6 0.5 0.0 2.2 0.3 0.5 0.0 2.5 0.2 2.3 6.6 0.9 0.8 63.2 38.6 0.0 0.0 0.0 0.3 11.7 0.0 0.1 TFEC "bHLHe34, TCFEC, TFECL" ENSG00000105967 "Transcription factor EC" O14948 7 115935148-116159896 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;kidney: 20.5;lymphoid tissue: 22.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 45.5;Kupffer cells: 56.3;Macrophages: 61.6;Microglial cells: 60.0;monocytes: 44.1;Proximal tubular cells: 77.8" "Cancer enhanced" "Detected in many" "renal cancer: 5.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 7.1;intermediate monocyte: 2.8;memory B-cell: 3.8;myeloid DC: 6.3;naive B-cell: 2.5;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 29 "B-cells: 3.8;dendritic cells: 6.3;monocytes: 7.1" "Cell line enhanced" "Detected in some" "HEL: 15.9;HUVEC TERT2: 11.0;THP-1: 21.5;TIME: 12.5;U-937: 24.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB032260, HPA063577" Approved Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB032260: AB_2202845, HPA063577: AB_2685047" "unprognostic (1.36e-1)" "unprognostic (1.08e-2)" "unprognostic (8.70e-2)" "unprognostic (1.91e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.26e-2)" "unprognostic (2.15e-1)" "unprognostic (6.54e-2)" "unprognostic (2.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.05e-3)" "unprognostic (2.92e-1)" "unprognostic (4.14e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-2)" 3.5 2.4 1.3 19.2 1.2 17.2 2.6 1.5 1.6 1.9 2.1 2.7 4.2 1.4 0.6 1.0 1.0 4.9 1.0 0.8 1.7 20.5 3.1 9.9 22.1 3.3 1.9 1.3 1.0 0.4 0.6 4.7 2.7 1.0 4.2 0.1 1.3 0.9 0.3 0.4 9.7 3.1 2.7 14.6 3.0 1.6 3.7 2.8 0.9 0.4 12.6 4.0 0.6 4.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 3.7 0.0 1.7 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 11.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 21.5 12.5 2.1 0.2 1.3 0.0 5.5 0.0 0.0 0.1 24.4 1.1 0.0 7.1 0.0 0.0 2.8 0.0 3.8 0.0 0.0 6.3 2.5 0.0 0.0 0.1 0.0 0.4 3.3 0.0 1.5 1.3 1.2 1.5 1.6 0.8 1.7 3.3 1.9 2.7 2.7 3.7 4.8 0.5 0.0 2.2 0.3 18.1 0.5 0.0 0.0 0.0 0.0 0.3 0.8 0.8 1.5 0.0 3.7 0.0 0.2 8.3 0.0 0.0 0.0 2.4 0.0 0.0 1.7 0.0 7.2 0.6 0.0 0.3 0.4 0.0 0.0 2.5 0.0 0.0 0.0 45.5 0.0 0.5 0.4 0.0 56.3 17.8 3.8 0.0 61.6 0.0 60.0 44.1 0.0 1.0 1.0 0.1 0.1 0.0 0.0 1.3 0.1 15.6 77.8 0.0 0.0 0.0 0.3 0.1 0.3 2.5 0.1 0.4 0.8 0.8 0.1 0.7 0.1 TGFBI "BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1" ENSG00000120708 "Transforming growth factor beta induced" Q15582 5 136028988-136063818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Sensory transduction, Vision" "Amyloidosis, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 457.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.8;Kupffer cells: 292.9;Langerhans cells: 251.2;Macrophages: 198.9;Pancreatic endocrine cells: 590.1;Smooth muscle cells: 326.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 77.3" "Group enriched" "Detected in many" 32 "classical monocyte: 252.3;intermediate monocyte: 149.1;myeloid DC: 156.9;non-classical monocyte: 121.4;plasmacytoid DC: 324.5" "Group enriched" "Detected in all" 46 "dendritic cells: 324.5;monocytes: 252.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 2857.3;GAMG: 2417.8;HSkMC: 2675.6;hTCEpi: 1915.6;LHCN-M2: 2269.4;U-2197: 1916.3;U-87 MG: 3667.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA008612, HPA017019" Enhanced "Secreted to blood" NA NA 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "HPA008612: AB_1857970, HPA017019: AB_2669511" "unprognostic (1.05e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.38e-3)" "prognostic favorable (1.17e-4)" "unprognostic (5.21e-3)" "unprognostic (5.53e-3)" "unprognostic (4.60e-2)" "unprognostic (8.71e-3)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.42e-3)" "unprognostic (2.26e-1)" "prognostic unfavorable (7.82e-10)" "unprognostic (8.81e-3)" "unprognostic (1.73e-2)" "unprognostic (3.42e-1)" "unprognostic (1.70e-3)" 133.2 55.3 9.5 164.0 10.4 25.9 112.2 10.0 25.5 51.8 51.9 92.8 48.2 59.7 41.6 28.7 59.7 146.1 95.5 10.4 11.5 124.0 132.1 89.7 66.2 15.8 11.9 25.4 22.4 18.4 77.6 457.6 15.7 69.5 84.4 2.8 68.3 58.9 34.8 314.1 65.3 291.0 12.2 121.1 67.4 7.6 77.3 57.7 40.4 41.7 44.4 138.9 39.0 14.0 102.2 405.6 0.8 3.8 1104.3 354.4 1.5 295.1 42.9 209.9 125.1 186.4 1276.3 0.1 181.6 2857.3 2417.8 498.0 1.0 981.4 208.0 2.3 0.1 0.1 451.6 501.3 718.9 0.7 3.9 2675.6 1915.6 77.9 93.1 827.5 188.1 0.2 0.2 3.8 2269.4 4.8 0.7 0.7 13.1 5.1 0.9 0.4 24.3 3.4 96.7 8.8 1.3 0.7 473.7 15.5 3.9 452.8 3.7 110.9 745.6 1419.3 59.8 1916.3 1139.6 0.3 0.7 1.9 3667.3 0.9 1077.5 1.6 252.3 1.0 0.9 149.1 1.0 1.0 1.0 2.0 156.9 0.4 0.3 1.0 5.3 6.2 121.4 324.5 0.5 108.5 9.5 10.4 10.0 25.5 10.4 11.5 15.8 11.9 15.7 12.2 77.3 14.0 12.4 3.2 21.4 0.0 6.3 119.4 4.8 141.8 4.6 0.4 1.9 5.5 8.9 4.3 21.8 1.8 0.0 9.9 146.5 1.3 0.0 67.5 2.4 2.3 57.9 16.4 3.5 8.8 0.4 112.6 8.5 113.5 0.5 1.7 5.1 0.0 21.0 25.7 251.8 1.7 0.0 7.8 6.1 292.9 251.2 1.9 10.2 198.9 49.8 4.7 151.1 0.3 6.2 0.0 0.0 590.1 0.0 2.2 1.9 1.0 0.1 2.7 8.5 0.2 26.3 156.8 326.1 0.2 0.9 1.9 55.7 19.4 8.5 10.8 0.9 2.5 TK2 SCA31 ENSG00000166548 "Thymidine kinase 2" O00142 16 66508003-66552544 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041162 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041162: AB_10961178" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.27e-3)" "unprognostic (3.94e-1)" "unprognostic (2.93e-1)" "unprognostic (1.10e-1)" "unprognostic (4.83e-2)" "unprognostic (3.35e-2)" "unprognostic (3.45e-1)" "unprognostic (3.59e-2)" "unprognostic (2.85e-1)" "prognostic favorable (2.18e-6)" "unprognostic (3.05e-2)" "unprognostic (1.74e-1)" "unprognostic (2.71e-1)" "unprognostic (7.05e-2)" 48.1 30.2 24.2 11.8 27.6 8.5 25.6 24.7 25.7 20.0 19.7 15.0 10.9 16.2 29.3 12.3 19.0 21.1 19.2 24.1 25.6 25.1 37.3 18.7 11.7 26.5 27.8 26.8 24.4 38.0 22.4 15.1 27.6 19.2 12.7 11.7 22.6 19.9 11.5 12.7 13.5 18.9 27.5 23.0 15.7 33.9 25.8 13.0 25.6 14.6 9.9 17.8 15.4 28.3 13.3 26.5 12.1 14.5 64.3 52.2 0.7 22.0 22.3 15.1 16.8 6.5 26.4 0.1 23.8 63.9 19.0 11.8 5.3 17.7 10.4 8.5 6.2 4.1 17.2 12.9 45.1 5.6 9.2 39.4 15.3 18.5 26.1 62.5 19.9 13.1 6.8 28.1 37.9 4.1 5.5 14.9 5.9 5.1 15.4 7.0 21.0 28.1 44.1 12.5 4.4 8.9 63.2 6.1 26.9 6.6 9.6 16.3 29.7 30.8 15.9 26.3 7.6 30.3 12.2 11.6 38.9 5.7 18.4 5.6 9.4 6.0 1.8 5.1 1.2 0.1 1.3 1.0 8.7 1.7 0.6 0.9 8.5 2.7 4.3 1.8 1.2 2.5 24.2 27.6 24.7 25.7 24.1 25.6 26.5 27.8 27.6 27.5 25.8 28.3 25.0 22.4 9.3 19.6 7.3 5.7 5.1 5.8 12.5 15.5 15.4 11.4 8.0 17.2 7.5 22.0 22.9 10.0 7.6 6.0 9.8 15.7 25.2 15.2 23.2 14.4 9.6 10.3 10.1 22.4 6.0 19.9 11.7 13.0 24.8 20.6 31.1 48.9 21.7 21.9 12.0 6.5 2.0 55.6 10.1 40.5 23.3 23.6 10.6 10.3 22.6 18.4 12.3 14.6 19.4 28.9 3.3 19.2 12.4 4.3 14.4 45.9 9.0 20.5 0.0 14.4 10.6 48.9 11.1 9.6 3.8 2.9 8.6 22.2 7.6 4.2 TKT ENSG00000163931 Transketolase P29401 3 53224712-53256052 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 667.0" "Cell type enhanced" "Detected in all" "Kupffer cells: 696.7;monocytes: 624.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 447.9;eosinophil: 274.4;intermediate monocyte: 199.0;myeloid DC: 203.8;neutrophil: 375.3;non-classical monocyte: 242.6" "Group enriched" "Detected in all" 9 "dendritic cells: 203.8;granulocytes: 375.3;monocytes: 447.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029480, HPA029481" Enhanced Enhanced Nucleoplasm NA NA 150000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA029480: AB_10599307, HPA029481: AB_10601895" "unprognostic (5.05e-2)" "unprognostic (3.34e-2)" "unprognostic (1.02e-2)" "unprognostic (1.77e-2)" "unprognostic (2.06e-1)" "unprognostic (1.02e-2)" "prognostic unfavorable (7.21e-6)" "unprognostic (6.78e-2)" "unprognostic (1.70e-1)" "unprognostic (4.73e-2)" "unprognostic (3.06e-3)" "unprognostic (1.36e-2)" "unprognostic (2.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.07e-1)" "unprognostic (3.29e-1)" "unprognostic (9.90e-3)" 152.2 93.2 78.0 66.2 80.0 667.0 71.9 93.2 82.3 59.7 60.5 73.2 84.2 44.7 19.2 168.5 53.7 97.2 27.4 72.3 96.9 68.2 58.1 93.4 69.2 89.2 89.9 87.7 154.0 41.4 45.6 61.2 93.8 48.8 48.8 21.7 54.9 50.9 12.8 47.0 58.1 51.6 77.4 99.8 66.1 20.2 87.9 82.9 116.1 15.2 67.4 130.9 85.5 97.2 313.0 1542.9 216.0 241.5 470.8 570.8 439.5 206.2 353.8 348.8 330.8 430.1 779.3 388.5 96.8 302.9 673.3 438.3 377.9 775.8 102.4 131.0 210.3 259.6 1022.2 655.2 573.9 321.4 168.1 416.0 437.5 418.5 213.7 949.2 444.9 323.8 188.3 164.7 144.5 381.6 338.6 358.1 737.1 603.0 367.9 201.1 98.5 726.2 550.3 520.2 139.6 103.7 383.4 605.3 365.1 656.7 188.8 437.4 335.9 107.2 164.2 320.0 401.9 94.5 190.3 235.7 234.4 321.0 203.8 51.5 447.9 274.4 17.8 199.0 22.8 39.7 25.8 20.6 203.8 21.1 26.6 20.7 375.3 30.8 242.6 34.4 36.7 312.4 78.0 80.0 93.2 82.3 72.3 96.9 89.2 89.9 93.8 77.4 87.9 97.2 79.5 134.6 125.6 46.7 92.1 79.4 384.6 325.3 287.4 41.0 99.3 80.5 14.9 75.8 149.5 62.5 29.2 349.0 69.7 139.1 80.3 197.7 6.5 87.4 79.6 81.8 52.6 150.3 16.9 269.8 249.8 80.2 168.7 95.5 62.7 123.6 75.0 83.4 256.0 37.0 23.9 149.6 142.4 696.7 110.5 8.9 157.2 333.3 76.5 17.8 624.4 88.8 46.4 17.1 39.3 193.6 81.4 106.8 109.4 337.7 141.5 219.1 99.2 46.3 52.6 35.9 102.1 16.8 30.6 409.3 67.1 413.6 78.8 427.2 276.7 413.6 TLR5 "FLJ10052, MGC126430, MGC126431, SLEB1, TIL3" ENSG00000187554 "Toll like receptor 5" O60602 1 223109404-223143248 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 20.2" "Cell type enhanced" "Detected in many" "Club cells: 23.3;Glandular and luminal cells: 25.6;Kupffer cells: 29.5;Microglial cells: 23.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 30.8;intermediate monocyte: 28.1;myeloid DC: 23.4;neutrophil: 25.3;non-classical monocyte: 12.4" "Group enriched" "Detected in many" 11 "dendritic cells: 23.4;granulocytes: 25.3;monocytes: 30.8" "Cell line enhanced" "Detected in some" "A-431: 2.1;HaCaT: 3.2;OE19: 1.8;SK-BR-3: 2.0;T-47d: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009013 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB009013: AB_2240732" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-2)" "unprognostic (3.81e-2)" "unprognostic (3.09e-2)" "unprognostic (6.83e-2)" "unprognostic (1.49e-2)" "unprognostic (2.71e-1)" "unprognostic (4.23e-3)" "unprognostic (1.46e-1)" "unprognostic (3.69e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (1.06e-3)" "unprognostic (5.60e-2)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" 3.5 1.9 2.6 4.7 2.2 0.5 8.6 2.5 2.4 6.0 2.3 2.0 1.6 2.1 2.6 4.9 5.1 4.5 1.7 2.3 2.7 4.1 1.6 6.2 4.3 3.7 3.5 20.2 4.0 4.4 0.7 3.4 3.6 3.3 2.1 0.7 10.3 2.4 1.4 2.0 2.1 2.6 3.1 2.9 4.1 1.8 3.4 2.5 1.9 1.6 5.0 4.0 2.4 5.0 2.1 0.2 0.3 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.2 0.0 3.2 0.0 0.2 0.2 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.2 0.1 0.8 0.4 0.0 0.0 0.3 0.5 0.1 1.1 1.8 0.0 0.0 0.0 0.1 0.9 0.4 0.8 0.3 0.6 2.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.3 0.2 0.0 30.8 0.4 0.2 28.1 0.4 0.2 1.5 0.4 23.4 0.1 2.3 0.7 25.3 0.4 12.4 0.3 1.2 10.9 2.6 2.2 2.5 2.4 2.3 2.7 3.7 3.5 3.6 3.1 3.4 5.0 1.0 3.2 17.0 0.0 0.2 0.5 5.8 18.9 4.6 0.1 10.6 5.3 1.7 14.3 23.3 22.0 2.1 1.5 0.3 0.4 3.9 5.9 4.6 13.6 2.0 2.1 1.2 0.0 0.5 3.8 0.3 7.7 3.1 25.6 2.5 4.6 0.7 0.7 18.1 0.0 1.0 0.6 6.1 29.5 3.1 5.7 9.3 22.4 3.6 23.4 14.4 1.4 0.0 1.5 0.1 2.4 0.1 8.6 0.1 3.0 0.5 0.1 11.0 0.2 0.0 4.2 4.1 5.4 5.5 15.9 1.6 0.8 1.7 4.1 1.5 6.3 TMEM150B "DRAM3, TMEM224, TTN2" ENSG00000180061 "Transmembrane protein 150B" A6NC51 19 55312801-55334048 "Predicted membrane proteins, Transporters" Autophagy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "intestine: 64.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 18.1;Kupffer cells: 11.8;monocytes: 8.0;Proximal enterocytes: 68.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.9;monocytes: 5.7" "Cell line enhanced" "Detected in some" "CACO-2: 8.3;HMC-1: 3.8;THP-1: 2.9;U-937: 18.1" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "unprognostic (5.76e-2)" "unprognostic (4.94e-2)" "unprognostic (5.33e-2)" "unprognostic (6.70e-2)" "unprognostic (5.51e-2)" "unprognostic (1.35e-1)" "unprognostic (5.35e-2)" "unprognostic (4.00e-2)" "unprognostic (4.74e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (6.14e-6)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (2.45e-1)" "unprognostic (1.18e-2)" 3.7 1.8 0.5 5.8 0.8 0.7 1.1 0.4 1.0 0.3 1.2 10.2 64.1 0.4 0.1 0.6 0.8 2.9 0.8 0.4 0.7 3.2 2.2 11.9 3.5 1.3 0.7 0.3 0.9 0.1 0.2 5.6 1.6 0.3 7.3 0.0 0.6 0.4 0.2 0.2 57.0 4.1 0.5 5.7 1.4 0.5 3.4 0.7 0.3 0.2 1.6 2.0 0.3 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.6 0.0 1.1 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.9 0.0 0.0 0.1 0.1 0.1 1.8 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 18.1 0.1 1.9 5.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.5 0.8 0.4 1.0 0.4 0.7 1.3 0.7 1.6 0.5 3.4 1.3 0.0 0.0 0.0 0.0 0.6 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.5 1.5 0.0 1.8 0.0 0.0 0.0 18.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.8 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.1 6.7 0.0 0.7 3.5 0.0 11.8 1.3 0.0 0.0 3.2 0.0 0.0 8.0 0.0 0.0 0.0 0.9 0.3 1.4 0.0 0.9 0.6 68.9 0.6 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 3.7 0.3 TMEM170B ENSG00000205269 "Transmembrane protein 170B" Q5T4T1 6 11537749-11583524 "Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.2" "Cell type enhanced" "Detected in many" "Astrocytes: 39.2;Excitatory neurons: 57.3;Inhibitory neurons: 52.3;Kupffer cells: 36.8;Macrophages: 31.5;monocytes: 45.8;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "THP-1: 22.1;U-937: 16.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055134 Uncertain Approved Centrosome NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Centrosome "HPA055134: AB_2682709" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.51e-1)" "unprognostic (2.71e-4)" "unprognostic (6.67e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (4.62e-3)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (2.45e-5)" "unprognostic (3.49e-1)" "unprognostic (1.26e-1)" "unprognostic (4.27e-2)" "unprognostic (1.36e-1)" "unprognostic (2.56e-4)" "unprognostic (3.97e-2)" 7.0 2.8 8.1 4.3 9.0 25.2 2.3 8.6 10.7 1.6 2.2 2.3 0.7 2.4 3.1 1.3 1.6 1.7 2.1 10.2 6.9 3.7 8.7 3.8 1.7 8.4 7.7 2.2 1.9 2.9 2.7 2.5 9.1 1.9 1.1 9.5 1.5 2.0 6.2 0.9 1.2 2.9 6.8 3.9 1.5 3.4 7.7 1.9 2.6 7.3 1.2 1.5 0.9 7.4 0.9 1.5 8.8 7.9 1.6 0.1 1.8 0.8 2.0 1.2 1.4 0.5 0.5 7.3 4.0 0.5 2.3 0.0 10.0 0.6 3.1 2.1 5.3 4.1 1.0 1.2 0.5 6.6 4.1 0.6 0.1 1.3 0.0 2.0 0.8 6.7 0.2 0.1 1.8 1.3 8.0 11.3 2.5 0.8 1.2 4.1 8.4 1.2 0.9 1.8 6.0 5.1 0.5 2.9 3.3 12.4 2.9 22.1 0.1 1.6 1.9 3.2 2.1 6.3 13.4 6.4 1.4 16.6 2.2 0.9 0.8 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.2 0.9 0.0 0.1 8.1 9.0 8.6 10.7 10.2 6.9 8.4 7.7 9.1 6.8 7.7 7.4 2.7 3.2 2.0 39.2 2.9 1.8 0.6 0.2 0.6 13.2 2.2 1.8 6.5 1.5 1.5 0.0 4.2 2.1 11.8 0.5 5.9 0.6 0.5 1.9 1.8 2.3 1.8 0.8 57.3 1.4 0.3 2.3 0.5 2.1 1.3 5.1 2.2 8.4 7.0 25.2 52.3 0.3 0.0 36.8 13.2 0.4 0.9 31.5 0.0 21.5 45.8 13.7 2.1 31.7 27.1 0.9 0.3 1.5 0.5 1.1 0.0 5.4 0.1 8.3 6.6 4.1 3.7 7.5 4.8 0.2 0.9 1.9 1.4 1.7 0.8 0.5 TMEM205 "MBC3205, UNQ501" ENSG00000105518 "Transmembrane protein 205" Q6UW68 19 11342776-11346518 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 405.8;Hepatocytes: 520.1;Late spermatids: 662.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041504 Approved Approved "Nucleoplasm,Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "Nucleoplasm, Nuclear membrane" "HPA041504: AB_10795595" "unprognostic (2.54e-2)" "unprognostic (2.60e-2)" "unprognostic (7.19e-2)" "unprognostic (1.57e-2)" "unprognostic (6.83e-2)" "unprognostic (1.80e-1)" "unprognostic (5.04e-3)" "unprognostic (3.77e-2)" "unprognostic (1.01e-2)" "unprognostic (5.56e-3)" "unprognostic (2.70e-2)" "unprognostic (1.19e-1)" "unprognostic (8.10e-2)" "unprognostic (5.78e-2)" "unprognostic (8.18e-2)" "unprognostic (1.20e-1)" "unprognostic (1.45e-1)" 70.3 177.5 111.5 36.8 113.2 55.2 76.0 110.7 142.9 92.8 135.4 73.8 62.3 69.5 92.6 53.7 85.2 61.1 119.7 117.2 122.4 139.2 276.9 73.9 38.9 112.8 113.1 86.8 155.0 210.0 97.4 53.6 114.0 93.2 36.4 25.9 92.4 78.7 122.2 74.3 57.2 42.2 113.6 62.6 86.3 78.8 113.6 39.3 132.1 66.0 34.1 92.4 64.0 122.7 95.5 229.7 28.5 96.2 54.1 64.5 52.6 35.2 80.9 75.9 59.4 70.0 29.5 84.7 209.3 71.6 74.5 95.6 40.5 106.6 50.5 100.7 39.2 23.0 76.5 117.7 135.9 38.9 69.8 61.3 106.7 48.7 81.0 78.5 92.3 79.9 70.4 349.8 47.0 238.8 58.6 108.9 49.9 123.0 174.5 54.3 43.4 225.9 186.9 169.0 50.2 76.7 37.3 151.1 88.1 33.1 132.2 111.3 54.0 94.3 36.2 104.4 80.2 207.0 225.3 51.5 90.4 172.2 74.0 31.8 336.5 36.7 67.2 150.0 67.9 112.7 54.7 58.5 208.2 95.8 43.9 52.2 52.6 55.8 91.0 150.9 73.7 175.8 111.5 113.2 110.7 142.9 117.2 122.4 112.8 113.1 114.0 113.6 113.6 122.7 80.5 67.3 70.5 40.1 44.1 51.5 135.9 281.3 62.0 32.5 113.3 134.4 68.5 175.8 202.3 152.6 12.5 123.7 27.7 53.7 60.7 159.2 405.8 63.2 65.8 72.4 117.6 14.5 30.8 162.7 83.0 76.4 26.0 97.0 29.2 45.4 69.3 520.1 94.4 26.9 27.3 81.4 136.3 67.5 50.0 662.3 80.8 61.2 96.0 5.6 62.1 91.9 19.6 17.6 22.2 97.7 68.6 68.1 70.7 136.7 104.1 224.6 69.3 33.1 46.0 76.3 70.9 38.1 15.6 46.4 54.0 96.7 29.8 101.6 79.3 130.9 TMEM45A "DERP7, FLJ10134" ENSG00000181458 "Transmembrane protein 45A" Q9NWC5 3 100492619-100577444 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skin 1: 475.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 425.3;Club cells: 841.5;Early spermatids: 207.3;Suprabasal keratinocytes: 254.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 406.9;ASC TERT1: 118.3;HSkMC: 125.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA062101 Uncertain Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "HPA062101: AB_2684682" "unprognostic (5.92e-3)" "unprognostic (5.44e-2)" "unprognostic (2.11e-1)" "unprognostic (1.43e-3)" "unprognostic (7.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (2.37e-1)" "unprognostic (2.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.18e-11)" "unprognostic (1.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.02e-5)" "unprognostic (2.68e-2)" 19.4 18.1 1.4 11.7 3.3 2.0 42.8 1.7 2.5 38.4 2.3 10.3 3.6 18.3 3.2 16.5 20.9 18.9 21.9 1.5 1.8 3.7 99.0 13.1 2.6 1.9 1.9 11.9 23.3 2.7 22.9 40.9 1.8 9.1 6.6 1.7 26.9 6.3 3.2 475.1 6.4 25.4 1.7 5.0 7.0 13.3 1.9 1.6 9.1 2.5 50.7 19.5 79.5 2.1 28.6 2.0 2.7 9.6 406.9 118.3 0.3 66.9 62.0 9.4 84.8 2.5 0.6 0.0 32.6 44.1 24.6 31.9 2.4 13.0 23.4 7.2 8.4 23.9 9.3 8.0 25.7 0.4 1.5 125.4 7.4 17.1 25.4 39.0 3.5 0.0 0.6 3.2 22.6 0.3 0.1 0.7 3.2 0.0 16.8 0.0 23.3 0.4 0.6 1.0 2.9 19.4 16.4 8.5 7.3 18.2 0.8 13.6 9.3 62.9 44.3 0.5 15.2 53.8 32.9 0.1 49.7 1.9 42.6 0.0 0.9 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.0 0.6 1.4 3.3 1.7 2.5 1.5 1.8 1.9 1.9 1.8 1.7 1.9 2.1 1.6 60.9 61.4 0.7 3.0 94.6 5.4 425.3 9.6 3.2 19.1 8.9 2.5 1.5 841.5 0.0 0.0 2.6 0.4 0.2 0.0 7.5 207.3 3.0 79.1 8.9 1.2 1.3 0.8 14.9 46.3 56.3 2.0 2.0 65.0 10.7 15.0 137.1 5.8 8.4 2.4 2.0 63.1 6.5 25.4 25.4 16.1 6.6 23.2 13.1 1.1 3.5 0.0 16.1 11.8 6.5 2.6 27.8 26.8 3.1 0.3 0.2 121.0 0.9 6.6 22.8 56.6 1.5 3.3 5.4 254.9 7.5 6.4 26.7 0.1 4.4 TNFSF13 "APRIL, CD256" ENSG00000161955 "TNF superfamily member 13" O75888 17 7558292-7561608 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 141.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 10.4;Basal squamous epithelial cells: 8.0;Erythroid cells: 5.9;Gastric mucus-secreting cells: 11.2;Macrophages: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 438.1;intermediate monocyte: 420.9" "Group enriched" "Detected in all" 12 "dendritic cells: 283.5;granulocytes: 158.9;monocytes: 438.1" "Cell line enhanced" "Detected in many" "EFO-21: 43.6;RPMI-8226: 39.9;RPTEC TERT1: 110.6;U-937: 44.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004863 Uncertain "Secreted to blood" NA NA 6770000 35000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "HPA004863: AB_1078187" "unprognostic (2.46e-2)" "unprognostic (2.20e-1)" "unprognostic (3.42e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (3.57e-1)" "unprognostic (3.32e-2)" "unprognostic (3.70e-2)" "unprognostic (3.75e-1)" "unprognostic (1.15e-1)" "unprognostic (6.95e-2)" "unprognostic (2.65e-1)" "prognostic favorable (1.30e-9)" "unprognostic (4.69e-2)" "unprognostic (1.42e-2)" "unprognostic (3.46e-1)" "unprognostic (3.38e-2)" 27.7 31.6 39.5 37.7 43.7 48.4 29.5 39.7 47.3 33.5 66.7 45.9 74.7 13.3 19.2 12.5 31.8 54.1 18.0 35.3 37.6 55.6 16.2 100.7 33.1 44.8 43.3 24.8 41.1 18.0 19.7 14.7 41.1 22.6 41.9 13.0 141.9 32.1 5.3 10.5 39.5 24.8 40.0 30.6 54.0 4.6 44.8 14.1 27.0 10.1 24.5 26.0 15.5 38.8 20.8 8.3 2.8 5.5 3.2 1.7 3.4 3.7 2.7 1.5 1.3 4.6 12.8 9.1 43.6 3.8 5.2 13.1 0.1 3.6 1.6 16.2 7.0 5.9 18.2 9.7 6.7 5.1 5.9 3.6 3.6 1.0 5.7 8.8 4.7 6.5 4.6 3.5 1.3 3.1 2.3 16.6 2.7 20.3 6.0 16.5 3.4 39.9 110.6 13.5 5.1 4.9 7.2 18.8 2.5 4.1 25.2 12.4 2.4 4.8 5.8 2.1 8.1 0.8 2.8 2.4 1.9 44.1 9.5 75.2 438.1 158.9 0.9 420.9 0.8 13.7 0.5 0.7 283.5 25.0 2.4 1.5 56.9 7.9 265.4 130.8 0.9 257.1 39.5 43.7 39.7 47.3 35.3 37.6 44.8 43.3 41.1 40.0 44.8 38.8 0.2 6.4 10.4 0.0 2.1 0.0 0.2 0.2 8.0 0.1 0.4 0.1 0.0 0.0 2.0 1.8 0.0 0.0 0.1 1.0 0.0 0.4 0.0 0.2 0.1 0.0 1.2 5.9 0.0 0.2 0.0 2.9 11.2 0.4 2.5 0.1 0.0 0.0 0.4 0.0 0.0 0.6 0.0 1.2 0.0 0.0 0.0 19.5 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.2 0.7 0.3 1.5 0.2 0.0 0.1 0.2 0.0 0.0 2.6 0.0 0.0 0.8 0.1 0.6 0.2 TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.5;Kupffer cells: 141.1;Langerhans cells: 246.7;Macrophages: 170.4;monocytes: 509.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 505.4" "Group enriched" "Detected in all" 11 "dendritic cells: 206.4;granulocytes: 505.4;monocytes: 350.9" "Cell line enriched" "Detected in some" 7 "U-937: 167.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 393000 790000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (6.48e-2)" "unprognostic (3.05e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (2.61e-2)" "unprognostic (7.99e-2)" "unprognostic (8.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.53e-11)" "unprognostic (1.23e-1)" "unprognostic (4.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" 8.2 5.3 2.8 25.9 2.6 20.1 4.7 2.7 4.1 2.2 5.8 5.5 10.7 1.4 1.5 4.8 2.4 12.4 3.8 2.7 3.1 1.5 5.3 10.9 20.9 6.3 3.0 1.1 1.5 0.7 1.0 9.0 4.2 1.7 8.4 0.4 3.3 1.2 1.4 1.9 6.4 5.0 4.6 15.9 5.0 1.2 3.5 5.3 3.0 1.6 17.7 11.1 2.1 5.2 0.1 0.4 0.1 0.1 0.7 0.8 0.2 0.3 0.8 0.6 2.1 0.1 1.7 0.3 0.2 0.2 0.3 0.1 0.0 0.1 0.1 11.6 0.0 0.9 0.4 0.0 0.4 10.2 0.3 2.0 0.4 0.2 0.1 0.4 0.1 0.1 0.1 0.6 1.2 0.0 0.1 5.3 0.1 1.1 0.0 0.0 0.2 0.0 0.6 0.3 1.3 0.3 0.0 0.0 0.4 0.2 0.1 22.3 0.2 0.3 0.0 0.0 0.4 10.0 0.3 0.1 10.3 167.0 1.7 12.6 350.9 100.1 5.4 272.3 31.5 4.4 21.5 4.4 206.4 7.1 9.9 3.4 505.4 5.0 234.1 77.8 19.4 165.8 2.8 2.6 2.7 4.1 2.7 3.1 6.3 3.0 4.2 4.6 3.5 5.2 3.1 16.0 12.9 6.2 7.0 7.1 0.7 1.3 1.2 0.9 2.4 3.2 0.6 10.0 4.2 5.5 0.0 0.5 40.6 0.6 1.9 2.3 1.2 0.4 0.7 3.6 1.2 14.5 18.1 32.5 1.1 29.6 3.1 0.5 5.1 0.9 3.9 2.8 87.5 0.0 11.2 0.9 0.0 141.1 246.7 0.6 5.3 170.4 8.8 15.0 509.4 0.2 5.2 55.3 5.1 1.7 0.5 1.9 1.5 2.7 2.2 1.3 2.0 0.3 6.6 1.4 4.1 0.1 0.7 0.5 4.7 1.1 10.5 1.2 1.8 3.1 TNFSF15 "MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A" ENSG00000181634 "TNF superfamily member 15" O95150 9 114784652-114806039 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 25.6;Basal squamous epithelial cells: 14.8;Endometrial ciliated cells: 15.7;Glandular and luminal cells: 28.9;Squamous epithelial cells: 13.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 13.2;hTEC/SVTERT24-B: 8.6;HUVEC TERT2: 16.7;OE19: 16.0;RT4: 16.5;TIME: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012948, HPA046522" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Secreted to blood" NA NA 1110000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA012948: AB_1858024, HPA046522: AB_2679683" "unprognostic (3.41e-1)" "unprognostic (2.06e-2)" "unprognostic (3.76e-1)" "unprognostic (1.52e-2)" "unprognostic (3.26e-2)" "unprognostic (1.67e-2)" "unprognostic (1.64e-1)" "unprognostic (2.29e-2)" "unprognostic (5.40e-2)" "unprognostic (1.38e-1)" "unprognostic (7.78e-2)" "unprognostic (2.09e-1)" "unprognostic (8.64e-5)" "unprognostic (1.97e-2)" "unprognostic (1.87e-3)" "unprognostic (1.68e-3)" "unprognostic (4.46e-3)" 0.8 0.7 0.1 2.5 0.2 0.1 0.9 0.1 0.5 1.5 0.1 2.3 9.5 1.0 0.9 1.2 0.9 1.9 0.0 0.1 0.2 4.5 0.2 4.1 0.8 0.3 0.1 0.1 0.1 0.8 0.1 4.4 0.2 4.1 2.0 0.0 4.8 1.9 0.1 0.6 3.5 2.0 0.0 0.5 2.9 0.1 0.2 0.6 0.9 0.0 1.0 4.7 0.7 0.4 0.5 4.4 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.1 0.2 3.0 1.6 0.0 0.0 0.5 13.2 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 8.6 0.0 0.0 16.7 0.0 0.0 0.9 0.4 0.6 0.0 0.0 0.3 16.0 0.0 0.0 0.1 0.0 0.1 16.5 0.1 0.0 0.0 0.7 0.0 5.6 1.2 0.0 7.7 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.1 0.5 0.1 0.2 0.3 0.1 0.2 0.0 0.2 0.4 0.2 12.8 12.1 0.0 0.1 0.5 7.7 25.6 14.8 0.3 3.7 3.7 0.6 1.5 4.9 7.3 0.0 0.7 0.4 8.0 0.0 4.9 0.7 15.7 2.9 0.3 0.0 0.0 0.1 2.0 0.2 1.2 8.2 28.9 0.0 0.0 0.0 0.0 2.3 0.0 0.7 2.4 2.0 0.3 5.1 0.1 0.0 5.0 0.0 0.0 5.3 0.1 0.0 0.0 0.1 1.3 0.5 0.4 1.2 4.9 8.9 9.3 1.0 0.3 0.0 0.4 3.0 0.0 0.0 13.7 0.6 0.3 1.0 0.1 7.4 6.5 TPP1 "CLN2, LPIC, SCAR7, TPP-1" ENSG00000166340 "Tripeptidyl peptidase 1" O14773 11 6612768-6619448 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 261.6;Kupffer cells: 376.5;Macrophages: 219.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037709, HPA044868" Enhanced "Intracellular and membrane" NA NA 9500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA037709: AB_10672913, HPA044868: AB_2679122" "unprognostic (8.27e-3)" "unprognostic (5.85e-2)" "unprognostic (7.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (2.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.54e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (4.46e-4)" "unprognostic (3.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-2)" 74.7 145.9 71.0 74.6 81.0 111.7 44.3 80.3 81.4 53.8 120.1 59.1 59.9 74.0 43.1 39.5 47.1 65.1 56.3 70.6 78.4 71.6 92.7 81.5 77.7 85.2 82.6 49.7 36.2 54.2 63.6 94.2 81.0 38.9 59.7 48.5 42.5 57.5 31.4 39.5 73.3 92.0 74.7 135.0 48.4 20.0 83.3 47.4 45.7 39.0 60.9 68.4 42.8 90.4 26.1 48.1 25.9 50.5 309.9 160.1 21.8 50.9 220.7 36.9 62.0 20.1 122.5 37.4 32.6 136.6 220.2 85.8 48.3 68.7 57.9 37.3 27.6 32.2 23.8 54.9 210.9 45.8 182.6 231.8 104.5 45.9 102.6 240.4 158.8 32.9 59.8 124.6 110.4 30.2 16.6 52.4 18.0 61.5 57.1 36.1 21.6 77.0 62.8 38.2 4.5 20.4 52.6 44.6 91.0 76.5 30.8 79.7 188.0 119.7 33.1 101.1 19.8 92.3 95.3 14.0 139.8 101.7 64.5 67.0 167.1 38.2 39.9 171.2 30.0 35.1 31.4 41.0 185.9 37.0 20.1 27.2 27.5 29.1 125.1 93.1 60.3 138.8 71.0 81.0 80.3 81.4 70.6 78.4 85.2 82.6 81.0 74.7 83.3 90.4 32.0 25.6 37.3 31.6 53.0 23.7 28.4 29.8 13.1 24.8 21.1 23.9 41.8 50.1 26.8 16.5 12.5 35.4 71.0 55.2 5.9 42.2 11.8 13.3 30.2 40.7 16.7 37.5 12.5 13.4 45.3 40.3 16.3 24.8 62.2 25.6 75.7 81.0 261.6 15.2 12.4 31.3 26.4 376.5 126.5 11.2 27.1 219.8 90.7 15.9 156.0 37.9 49.4 8.0 21.9 17.4 44.1 26.4 26.4 23.5 99.7 51.6 14.5 23.8 6.6 19.0 20.3 0.8 1.1 27.6 20.0 88.0 42.2 24.6 32.5 26.5 TREX1 "AGS1, DRN3" ENSG00000213689 "Three prime repair exonuclease 1" Q9NSU2 3 48465811-48467645 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Exonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease variant, Neurodegeneration, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 53.6;Club cells: 24.5;Ionocytes: 40.7;Langerhans cells: 22.6;Melanocytes: 24.9;Respiratory ciliated cells: 29.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 67.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035437, HPA046721" Supported Supported Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA035437: AB_10672092, HPA046721: AB_2732531" 9.9 14.3 32.7 16.5 33.4 28.7 12.2 33.2 42.1 13.8 39.8 12.4 11.1 7.7 11.4 19.2 15.5 13.8 10.7 33.0 32.7 12.2 12.8 13.8 26.6 33.0 34.2 7.4 13.1 11.3 20.6 8.4 34.3 16.6 9.9 1.9 36.5 15.4 9.7 26.4 12.0 7.0 33.8 25.0 13.7 4.0 33.5 18.1 8.4 13.8 18.1 13.1 10.4 33.7 19.2 18.1 13.3 10.3 18.1 17.5 0.0 6.7 29.5 46.9 67.5 0.3 21.8 23.8 11.7 24.4 44.8 21.4 0.9 27.2 6.7 19.9 1.6 13.5 58.1 0.5 20.1 12.8 9.3 16.2 2.5 25.9 9.8 9.8 20.4 16.9 0.0 32.6 20.7 0.4 17.3 8.6 0.1 11.0 11.2 14.4 4.9 43.2 13.4 3.8 0.1 8.1 21.8 29.6 15.4 0.9 0.8 20.3 22.2 8.5 9.2 21.8 14.2 26.4 16.9 10.4 21.5 25.4 7.5 7.7 142.3 11.0 32.6 119.2 18.7 86.8 43.0 31.4 125.9 87.5 40.3 33.8 82.2 30.9 94.6 99.1 43.3 78.6 32.7 33.4 33.2 42.1 33.0 32.7 33.0 34.2 34.3 33.8 33.5 33.7 0.0 0.0 0.5 6.8 2.1 9.1 0.0 53.6 0.6 0.0 0.0 0.0 6.3 0.0 24.5 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 4.6 0.0 1.7 2.3 0.0 0.0 4.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.8 40.7 0.0 22.6 0.0 0.0 2.0 24.9 5.6 0.0 0.0 0.0 1.0 5.9 0.0 1.1 0.0 3.9 0.0 0.0 0.0 29.9 0.0 0.0 0.0 4.2 0.0 0.0 2.7 13.9 0.0 2.6 0.0 1.5 0.0 TRPM4 FLJ20041 ENSG00000130529 "Transient receptor potential cation channel subfamily M member 4" Q8TD43 19 49157741-49211836 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.2;Hepatocytes: 81.7;Intestinal goblet cells: 114.8;Paneth cells: 77.1;Undifferentiated cells: 88.9" "Cancer enriched" "Detected in all" 4 "prostate cancer: 85.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 3.3;granulocytes: 2.8;monocytes: 4.3" "Cell line enhanced" "Detected in many" "OE19: 32.7;RT4: 60.8;SK-BR-3: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041169 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA041169: AB_2677343" "unprognostic (8.20e-3)" "unprognostic (1.41e-1)" "unprognostic (7.86e-2)" "prognostic favorable (2.88e-7)" "unprognostic (1.62e-2)" "unprognostic (9.78e-2)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (3.33e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.53e-7)" "unprognostic (8.46e-3)" "unprognostic (2.16e-1)" "unprognostic (5.70e-2)" "unprognostic (1.00e-2)" 10.8 6.1 5.8 6.1 5.4 4.6 13.5 8.5 7.0 11.5 4.8 46.1 25.3 9.9 2.5 13.1 9.2 7.4 23.0 5.9 4.5 22.8 15.4 16.0 1.8 6.2 7.4 3.3 10.1 3.7 5.6 5.3 6.9 35.7 12.9 1.3 27.3 6.2 14.0 26.6 22.9 3.4 4.2 5.5 20.6 5.4 6.6 1.0 17.3 5.3 1.9 13.7 14.4 5.1 11.9 9.0 2.1 9.5 7.7 6.6 6.6 10.0 6.0 2.7 3.7 6.1 18.7 0.4 2.7 6.8 3.6 15.7 1.3 3.0 1.0 0.2 3.4 1.9 4.0 3.7 6.6 0.3 11.7 9.3 13.6 5.3 2.6 3.3 4.6 1.0 4.9 2.1 6.9 17.4 0.8 0.9 1.0 32.7 13.3 4.1 2.0 0.6 4.6 60.8 0.8 2.2 4.1 38.6 2.2 0.7 22.6 3.7 11.8 14.4 7.8 7.9 0.2 3.9 4.3 0.4 7.9 7.4 5.3 2.2 4.3 0.7 0.3 2.5 0.2 0.5 0.2 0.2 3.3 0.5 0.3 0.3 2.8 0.5 1.0 3.1 0.2 1.4 5.8 5.4 8.5 7.0 5.9 4.5 6.2 7.4 6.9 4.2 6.6 5.1 12.8 32.1 2.6 9.8 3.5 12.5 15.3 9.9 9.1 2.0 19.0 14.6 16.7 17.2 12.3 14.7 0.0 6.6 0.2 179.2 19.6 7.9 2.9 17.5 8.2 11.7 21.7 0.0 5.4 18.5 6.8 6.0 71.4 36.2 5.7 2.9 11.4 81.7 19.9 0.0 8.5 114.8 14.2 9.8 19.0 3.1 6.8 8.5 39.2 9.4 12.8 6.7 0.0 3.5 0.9 32.9 77.1 7.2 7.6 35.5 55.3 3.8 8.9 2.6 32.9 2.2 8.5 6.1 15.7 8.4 11.5 3.4 1.9 4.1 88.9 33.1 TRPS1 "GC79, LGCR" ENSG00000104447 "Transcriptional repressor GATA binding 1" Q9UHF7 8 115408496-115809673 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 60.8" "Cell type enhanced" "Detected in many" "Astrocytes: 758.7;Breast glandular cells: 243.2;Oligodendrocyte precursor cells: 280.5;Oligodendrocytes: 294.0" "Cancer enriched" "Detected in many" 8 "breast cancer: 49.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 4.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 47.4;SK-BR-3: 78.1;T-47d: 244.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060380, HPA071767" Enhanced Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA060380: AB_2684270, HPA071767: AB_2732185" "unprognostic (4.34e-2)" "unprognostic (4.65e-2)" "unprognostic (1.73e-2)" "unprognostic (2.57e-1)" "unprognostic (1.87e-1)" "prognostic favorable (9.42e-4)" "unprognostic (2.23e-3)" "unprognostic (2.08e-1)" "unprognostic (9.31e-2)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (3.02e-1)" "unprognostic (2.17e-2)" "unprognostic (1.93e-2)" "unprognostic (1.64e-1)" "unprognostic (1.78e-2)" "unprognostic (3.07e-3)" 4.4 3.1 15.5 5.7 14.3 7.6 60.8 10.5 14.7 10.9 10.1 5.9 0.9 9.9 3.4 14.2 5.5 10.0 3.8 17.0 13.5 5.4 2.1 4.7 4.9 32.5 31.5 5.2 1.1 5.3 2.6 2.8 24.2 9.4 2.7 4.1 12.0 8.4 2.6 10.6 2.1 10.6 18.4 4.2 2.7 12.5 27.5 2.4 5.7 3.3 4.0 5.1 14.1 16.3 3.1 0.6 5.9 0.3 5.4 19.8 0.6 4.9 11.3 3.1 5.2 0.5 4.9 2.4 0.0 12.7 2.6 0.1 22.9 4.3 3.5 0.3 6.9 0.1 10.3 0.2 7.2 0.0 0.3 9.5 4.4 8.6 15.8 8.9 2.7 0.3 1.1 37.7 6.0 47.4 0.2 0.0 1.1 1.1 4.8 0.2 0.2 30.0 4.9 0.3 5.2 3.9 2.5 78.1 3.2 2.8 244.8 2.1 0.2 13.7 6.9 4.0 9.7 10.1 0.3 4.5 14.4 0.0 9.2 0.0 4.5 0.0 0.9 1.9 0.9 0.5 1.0 1.0 1.7 0.8 0.9 0.9 0.8 1.0 1.4 0.6 0.5 0.8 15.5 14.3 10.5 14.7 17.0 13.5 32.5 31.5 24.2 18.4 27.5 16.3 10.0 6.4 3.0 758.7 13.3 9.4 20.0 10.3 34.1 9.2 243.2 125.1 4.6 2.8 9.2 18.4 43.8 0.1 18.7 0.1 11.7 2.9 95.0 58.5 35.7 7.5 0.0 5.5 128.3 2.9 0.2 26.8 4.6 63.5 12.7 0.3 3.6 1.1 16.5 0.0 148.2 0.0 8.2 55.2 104.1 163.2 25.1 55.5 21.4 171.4 32.5 10.6 5.2 280.5 294.0 2.7 0.0 28.2 10.1 16.9 0.0 23.7 8.9 35.9 6.6 60.2 28.2 1.8 8.3 73.6 12.5 0.3 25.6 19.5 0.0 11.2 TRPV4 "CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC" ENSG00000111199 "Transient receptor potential cation channel subfamily V member 4" Q9HBA0 12 109783087-109833406 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Charcot-Marie-Tooth disease, Disease variant, Dwarfism, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 50.8;salivary gland: 19.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 17.1;Cholangiocytes: 20.0;Cytotrophoblasts: 20.0;Kupffer cells: 19.6;Respiratory ciliated cells: 28.2;Syncytiotrophoblasts: 21.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 5 "hippocampal formation: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 7.9;BJ hTERT+: 9.5;EFO-21: 7.2;HaCaT: 14.2;HUVEC TERT2: 8.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007150 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA007150: AB_1080393" "unprognostic (2.98e-2)" "unprognostic (1.12e-2)" "unprognostic (2.33e-2)" "unprognostic (4.20e-3)" "unprognostic (6.25e-3)" "unprognostic (1.09e-2)" "unprognostic (7.95e-2)" "unprognostic (2.03e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "prognostic favorable (4.12e-5)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" 1.0 0.8 0.2 0.9 0.3 0.1 1.9 0.7 0.5 2.0 50.8 0.4 0.7 0.6 0.4 10.3 4.7 1.4 0.8 4.2 0.2 14.7 8.6 2.2 0.8 0.5 0.4 0.3 4.4 0.3 2.1 5.2 0.3 6.8 0.3 0.0 19.2 0.8 0.1 7.5 0.4 0.7 0.2 2.8 0.7 0.8 0.8 0.1 0.9 0.0 0.9 1.8 2.2 0.4 2.4 0.2 0.0 0.0 2.0 1.2 7.9 4.2 9.5 1.2 0.3 0.0 6.4 0.0 7.2 5.8 0.0 14.2 1.0 0.0 0.4 0.0 1.8 0.0 0.1 3.7 0.6 0.0 0.0 3.4 2.0 2.7 0.0 0.6 8.7 0.0 0.5 0.0 0.4 5.3 0.0 0.0 1.5 0.0 0.0 0.0 0.5 0.0 0.0 4.9 0.0 0.0 0.3 0.6 2.6 3.5 1.1 0.2 4.5 0.0 2.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.5 4.2 0.2 0.5 0.4 0.3 0.2 0.8 0.4 0.1 0.0 0.0 0.0 0.7 3.3 8.1 17.1 7.4 0.0 5.1 5.5 1.0 20.0 12.0 11.0 0.0 20.0 0.4 0.0 3.9 2.5 0.2 3.2 1.0 1.4 0.0 0.0 0.3 9.3 5.3 1.2 2.0 1.2 0.0 0.9 0.7 7.7 4.0 0.0 0.4 0.0 6.1 19.6 0.7 0.2 0.9 2.6 7.2 1.9 0.8 0.0 0.0 1.0 0.3 2.0 0.0 0.0 0.0 4.6 0.0 12.5 28.2 0.0 0.0 0.1 1.1 0.3 1.1 4.5 3.8 21.1 0.3 0.2 0.0 3.3 TSPAN4 "NAG-2, TETRASPAN, TM4SF7, TSPAN-4" ENSG00000214063 "Tetraspanin 4" O14817 11 842812-867116 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 194.2;Fibroblasts: 168.7;Hofbauer cells: 240.6;Leydig cells: 172.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 146.4;intermediate monocyte: 143.5;myeloid DC: 101.2;NK-cell: 95.6;non-classical monocyte: 39.9" "Group enriched" "Detected in all" 10 "dendritic cells: 101.2;monocytes: 146.4;NK-cells: 95.6" "Low cell line specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 142.8" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (6.39e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.88e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (1.24e-1)" "unprognostic (6.13e-2)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (9.49e-2)" "unprognostic (2.41e-2)" "unprognostic (1.29e-2)" "unprognostic (2.61e-2)" "unprognostic (2.41e-2)" "unprognostic (1.18e-1)" 129.1 37.1 15.8 29.6 14.7 11.8 102.0 17.9 18.7 90.9 44.1 60.3 13.7 84.2 9.2 26.1 85.8 54.1 57.6 15.6 17.4 60.8 37.6 101.4 46.3 17.1 16.7 91.3 32.5 17.6 24.2 61.6 15.6 52.9 10.5 2.5 34.2 33.7 25.7 56.3 43.3 27.5 15.5 85.0 37.0 16.8 18.2 13.2 79.9 22.9 12.7 66.8 71.8 12.9 30.7 238.7 40.8 73.6 61.2 121.4 27.5 153.0 182.5 118.4 81.3 49.5 37.5 2.3 60.4 221.3 68.2 11.3 14.5 145.6 22.2 20.4 17.4 32.5 75.7 71.6 201.4 10.4 38.9 211.5 26.1 42.8 129.0 116.1 78.5 12.5 13.5 184.5 115.8 64.6 7.0 13.0 52.3 39.2 172.7 24.2 29.1 55.4 138.3 2.0 48.0 28.6 75.8 83.6 162.1 17.4 118.5 7.7 116.0 134.2 53.4 27.3 52.2 10.2 1.5 4.5 138.5 11.1 121.8 0.1 146.4 0.1 7.4 143.5 4.6 6.9 3.7 7.2 101.2 5.4 6.2 11.7 3.4 95.6 39.9 7.0 3.6 65.2 15.8 14.7 17.9 18.7 15.6 17.4 17.1 16.7 15.6 15.5 18.2 12.9 194.2 105.8 68.5 6.5 5.6 47.5 22.2 78.8 13.6 9.5 19.4 38.6 9.5 74.4 24.6 31.3 4.2 39.5 8.1 1.7 7.9 82.6 2.1 5.9 43.2 117.3 0.0 12.0 0.6 16.7 31.9 168.7 5.6 10.8 37.2 62.8 97.5 28.2 240.6 13.5 2.9 2.6 4.1 109.9 71.5 7.3 172.7 70.3 147.7 11.2 19.2 43.8 8.2 2.5 0.3 61.3 0.3 95.2 9.3 15.7 0.3 34.7 5.8 6.7 59.2 23.9 67.5 4.7 31.5 6.1 32.8 16.8 10.2 44.7 1.1 6.1 TSPO "BZRP, DBI, IBP, MBR, mDRC, PBR, pk18, PKBS" ENSG00000100300 "Translocator protein" "B1AH88, P30536" 22 43151547-43163242 "Cancer-related genes, FDA approved drug targets, Predicted membrane proteins" "Lipid transport, Transport" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 690.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1429.2;Pancreatic endocrine cells: 1442.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 516.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011232, HPA046260, HPA072304" Uncertain Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "Vesicles, Cytosol" "CAB011232: , HPA046260: , HPA072304: " "unprognostic (5.29e-3)" "unprognostic (1.41e-1)" "unprognostic (3.31e-1)" "unprognostic (4.02e-3)" "unprognostic (3.95e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.16e-1)" "unprognostic (1.17e-1)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-2)" "unprognostic (3.03e-1)" "unprognostic (1.04e-1)" "unprognostic (2.34e-3)" 249.3 164.5 42.3 65.3 46.3 488.7 204.3 50.9 61.1 217.3 45.8 189.7 73.6 91.8 8.7 690.1 108.5 39.4 174.7 39.9 51.0 120.5 81.9 181.5 44.3 61.9 48.8 72.3 93.4 22.4 50.8 30.5 57.4 126.6 33.9 4.2 244.9 28.9 84.0 388.0 116.9 26.6 58.0 206.9 216.9 21.4 59.5 22.2 77.4 27.5 39.9 135.7 355.5 69.0 300.0 143.3 10.2 134.4 54.7 175.3 10.8 216.6 107.0 109.4 115.7 28.8 222.4 0.3 147.8 175.7 52.2 242.2 27.9 171.7 13.9 49.5 111.4 28.9 150.4 10.1 193.4 66.4 145.0 137.5 276.4 65.9 58.2 125.8 262.9 0.2 24.0 53.6 114.2 244.5 1.1 188.5 11.6 154.0 355.7 67.0 0.0 516.2 139.3 173.8 14.0 65.4 103.9 200.4 263.5 0.1 76.3 256.6 269.7 132.6 96.9 135.5 92.9 21.7 4.1 2.7 170.0 218.3 171.4 656.8 1678.5 931.0 314.7 1051.6 247.7 199.2 429.9 309.2 1170.2 266.9 325.9 264.3 1052.3 365.0 713.1 209.0 539.5 1585.6 42.3 46.3 50.9 61.1 39.9 51.0 61.9 48.8 57.4 58.0 59.5 69.0 225.5 160.3 140.0 3.6 88.9 366.8 392.3 1429.2 554.3 2.8 269.3 360.2 92.1 323.1 555.7 206.0 2.1 10.0 140.3 680.7 369.8 578.5 2.4 170.8 143.6 220.4 194.9 239.9 0.3 586.4 284.9 205.1 440.9 309.5 268.6 124.3 187.1 110.5 758.5 3.3 0.8 636.8 478.1 644.7 524.7 11.7 82.6 611.6 723.9 10.3 776.9 180.5 207.0 6.0 20.1 1442.1 705.9 157.6 76.3 526.2 471.9 180.7 283.2 19.4 105.2 108.2 197.8 2.8 4.5 1067.4 536.0 20.0 180.0 30.5 664.1 786.1 TXNRD2 "SELZ, TR, TR3, TRXR2" ENSG00000184470 "Thioredoxin reductase 2" Q9NNW7 22 19875517-19941820 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2 OS: 139.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002007, HPA003323" Supported Approved Mitochondria,Cytosol NA NA 2800000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 47: Cytotrophoblasts - Unknown function" "Mitochondria, Cytosol" "CAB002007: , HPA003323: AB_1080396" "unprognostic (3.17e-2)" "unprognostic (8.72e-2)" "unprognostic (4.30e-1)" "unprognostic (9.71e-3)" "unprognostic (7.25e-2)" "unprognostic (6.35e-2)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (2.83e-1)" "unprognostic (4.94e-3)" "unprognostic (2.49e-1)" "prognostic favorable (1.10e-7)" "unprognostic (2.47e-1)" "unprognostic (5.99e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" 10.5 44.4 11.9 8.9 12.0 14.5 12.3 18.1 19.3 11.7 21.2 14.9 10.3 10.6 6.2 10.2 10.6 6.2 30.0 12.9 11.9 24.8 65.4 13.6 9.1 11.8 12.1 16.5 15.9 13.5 14.4 9.8 11.5 26.8 4.6 4.4 15.4 8.2 23.0 10.9 12.0 5.1 11.3 16.9 26.4 14.6 12.4 4.9 15.2 16.1 6.1 11.8 10.4 11.8 19.4 39.2 3.5 14.9 6.9 9.6 8.8 18.8 21.1 31.8 23.4 36.7 19.4 10.9 43.2 19.0 32.7 33.2 17.8 25.2 12.1 21.6 46.5 18.8 34.4 22.4 12.9 21.1 8.4 9.2 18.5 16.2 13.8 12.9 91.3 2.2 106.4 17.4 24.8 47.1 7.2 30.1 17.7 46.9 27.6 10.5 85.2 10.0 19.3 21.0 19.1 16.4 32.0 39.9 21.8 5.8 33.7 27.6 52.2 23.0 139.5 19.8 38.4 17.6 14.0 6.9 22.4 15.5 30.3 2.7 10.5 5.8 3.5 8.2 2.6 3.9 3.0 3.2 7.8 2.6 3.9 3.2 0.9 3.8 7.9 2.9 2.1 4.6 11.9 12.0 18.1 19.3 12.9 11.9 11.8 12.1 11.5 11.3 12.4 11.8 5.6 16.0 23.6 11.1 10.3 4.2 23.1 15.1 3.4 22.1 11.4 9.1 16.7 15.7 15.7 20.2 10.4 60.7 8.8 14.7 58.7 22.0 26.4 9.8 8.4 14.4 1.2 33.1 9.2 32.0 24.3 12.4 23.4 10.0 1.3 27.6 8.9 49.5 25.9 10.1 8.5 16.9 20.3 22.0 7.8 18.2 15.5 14.6 5.4 10.3 27.2 18.7 10.3 8.5 7.2 22.3 13.9 9.1 12.2 17.8 15.6 52.0 16.6 11.0 6.6 11.3 13.3 10.9 14.0 6.4 5.3 42.0 11.4 36.4 16.4 15.7 UBR4 "KIAA0462, KIAA1307, RBAF600, ZUBR1" ENSG00000127481 "Ubiquitin protein ligase E3 component n-recognin 4" Q5T4S7 1 19074510-19210266 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" "Calmodulin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 271.0;Suprabasal keratinocytes: 252.9;Urothelial cells: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013394, HPA021046" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA 15000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Centrosome, Cytosol" "HPA013394: , HPA021046: AB_1858578" "unprognostic (1.37e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (2.02e-1)" "unprognostic (8.78e-2)" "unprognostic (9.77e-2)" "unprognostic (1.14e-3)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (9.14e-3)" "unprognostic (7.48e-2)" "unprognostic (2.53e-1)" "unprognostic (7.68e-3)" "unprognostic (4.30e-1)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.52e-1)" 56.2 62.8 48.2 23.0 46.0 79.8 49.8 38.7 48.4 57.4 47.6 69.6 20.9 61.7 35.7 55.4 52.3 29.6 58.7 45.8 46.0 74.7 82.7 71.9 25.7 51.5 46.4 75.3 53.5 35.5 70.7 27.5 54.9 67.2 22.7 44.6 48.0 27.0 129.1 161.9 59.7 26.0 35.2 62.8 70.6 105.3 45.9 34.6 56.5 45.0 25.7 90.0 59.2 44.7 61.4 60.7 53.5 39.7 97.6 50.0 46.2 46.5 48.8 49.5 44.7 97.2 51.3 36.6 42.3 61.7 43.3 40.8 42.3 46.3 46.0 30.6 37.5 83.8 63.3 64.1 68.6 51.9 53.4 45.0 57.9 100.8 96.3 48.1 54.9 63.7 58.5 32.9 47.6 43.6 24.7 62.9 43.5 124.3 33.6 34.0 41.7 31.0 44.7 35.2 37.7 37.4 55.0 31.1 39.9 48.6 21.7 40.4 85.9 57.4 36.1 69.0 52.8 38.8 25.2 41.5 39.3 79.3 50.3 39.8 28.7 4.7 4.9 5.9 4.2 7.4 4.4 2.9 14.2 4.0 3.9 3.7 15.4 4.4 2.1 6.5 3.4 8.3 48.2 46.0 38.7 48.4 45.8 46.0 51.5 46.4 54.9 35.2 45.9 44.7 28.1 35.3 37.6 85.5 30.3 271.0 124.6 28.9 28.5 57.5 22.1 23.9 19.1 37.1 30.4 31.3 152.2 24.7 34.2 31.6 13.7 41.3 21.4 39.8 32.0 30.8 17.5 48.4 58.9 40.9 17.0 32.2 44.9 50.4 19.6 32.9 31.1 94.1 63.2 79.1 61.8 29.2 12.2 43.0 48.7 28.7 30.7 46.4 49.8 34.7 64.4 28.8 21.6 51.8 44.5 61.0 16.7 35.7 26.4 59.1 57.9 135.6 39.1 48.5 19.7 28.3 30.1 44.8 21.0 28.0 252.9 33.9 32.7 34.5 20.1 236.5 UBXN11 "SOC, SOCI, UBXD5" ENSG00000158062 "UBX domain protein 11" Q5T124 1 26281328-26318363 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 131.1;Late spermatids: 327.4;Respiratory ciliated cells: 121.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 93.2;intermediate monocyte: 82.6;myeloid DC: 48.4;non-classical monocyte: 72.2" "Group enriched" "Detected in all" 4 "dendritic cells: 48.4;monocytes: 93.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028600, HPA031357" Approved Approved Nucleoli,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli, Cytosol" "HPA028600: AB_10604001, HPA031357: AB_2673840" "unprognostic (1.78e-3)" "prognostic favorable (2.54e-5)" "unprognostic (8.18e-2)" "prognostic favorable (1.90e-4)" "unprognostic (2.53e-1)" "prognostic favorable (4.90e-4)" "prognostic unfavorable (5.90e-6)" "unprognostic (8.41e-2)" "unprognostic (2.70e-1)" "unprognostic (4.41e-2)" "unprognostic (1.79e-3)" "unprognostic (1.89e-2)" "unprognostic (5.59e-3)" "unprognostic (5.00e-2)" "unprognostic (2.20e-1)" "unprognostic (3.25e-1)" "unprognostic (1.31e-2)" 10.5 10.8 23.2 9.5 25.2 19.3 10.6 17.8 35.1 11.6 45.1 8.4 3.4 9.5 14.7 6.2 31.2 5.1 11.0 26.8 23.9 19.1 7.8 17.7 8.0 25.3 27.9 13.4 11.1 8.0 31.3 4.3 22.0 11.5 2.7 15.0 9.4 6.5 5.6 7.6 8.0 4.1 24.3 21.8 8.8 48.4 25.0 6.8 25.1 3.4 3.9 8.5 7.5 20.1 26.4 11.7 5.7 11.6 4.1 3.1 19.7 5.7 8.8 15.6 11.3 4.6 22.8 15.3 8.5 3.6 10.3 14.0 3.5 9.3 3.9 7.7 13.6 2.6 18.1 11.5 7.2 11.2 5.0 4.7 9.9 26.3 6.7 4.9 4.3 11.1 10.2 10.3 5.4 11.8 6.4 5.4 11.5 7.4 8.8 13.1 4.2 13.8 8.7 3.8 26.9 6.3 14.1 13.1 10.2 2.9 10.3 10.7 4.2 8.9 13.4 13.4 8.7 9.7 29.8 17.7 11.0 15.4 7.5 2.2 93.2 4.6 9.0 82.6 11.4 12.7 13.6 10.8 48.4 16.2 15.2 9.7 6.8 6.1 72.2 7.5 12.5 41.7 23.2 25.2 17.8 35.1 26.8 23.9 25.3 27.9 22.0 24.3 25.0 20.1 4.3 0.0 1.1 5.5 18.8 21.4 15.7 23.4 5.2 11.9 13.2 15.5 1.3 5.7 16.2 23.9 22.9 9.9 10.0 5.5 13.7 14.7 131.1 78.6 9.2 5.1 9.0 6.7 7.0 8.7 20.8 10.0 17.9 8.3 10.2 11.9 6.1 3.0 20.9 23.5 5.1 5.9 18.3 62.4 35.3 327.4 12.8 59.9 10.6 2.8 41.9 24.2 12.3 2.0 1.6 7.6 2.5 10.1 9.5 9.8 1.2 26.7 121.2 54.9 19.7 6.6 11.5 26.1 24.0 5.1 13.4 7.3 23.7 8.7 8.3 12.1 UQCRC1 "D3S3191, QCR1, UQCR1" ENSG00000010256 "Ubiquinol-cytochrome c reductase core protein 1" P31930 3 48599002-48610976 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 766.7;tongue: 882.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 662.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002815, HPA003525, CAB033782" Enhanced Supported Mitochondria NA NA 250000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB033782: AB_2213631, HPA002815: AB_1080486, HPA003525: AB_1080484" "unprognostic (1.29e-1)" "unprognostic (3.15e-3)" "unprognostic (6.91e-3)" "unprognostic (1.06e-1)" "unprognostic (1.66e-1)" "unprognostic (9.91e-2)" "unprognostic (8.53e-2)" "unprognostic (1.99e-1)" "unprognostic (3.11e-2)" "unprognostic (9.14e-2)" "unprognostic (3.37e-1)" "unprognostic (7.20e-2)" "prognostic favorable (2.35e-10)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "unprognostic (1.02e-1)" "unprognostic (6.72e-2)" 66.0 58.2 93.7 46.9 97.1 62.4 55.0 117.3 110.1 50.7 127.2 156.9 156.3 35.5 50.4 78.9 66.2 33.9 387.7 96.7 115.0 131.3 149.0 42.1 42.8 111.0 101.7 36.1 87.4 192.2 30.6 56.0 114.6 51.8 129.6 52.9 105.9 77.5 766.7 78.6 125.4 62.8 99.3 41.0 103.3 52.1 111.6 72.7 48.4 882.7 58.0 63.5 40.0 101.4 118.2 169.6 136.7 145.0 147.5 117.0 225.2 129.4 206.1 196.5 178.9 272.8 107.1 193.4 94.4 143.2 274.1 123.6 171.6 280.9 91.7 138.3 173.8 214.7 186.7 317.1 186.9 164.4 152.2 150.9 293.6 183.2 274.6 167.5 172.5 173.7 110.5 107.1 152.5 192.0 156.7 241.6 157.6 229.6 324.2 103.4 138.1 273.5 235.8 178.7 84.4 107.5 182.8 218.7 211.8 92.0 163.1 178.0 112.5 107.7 153.7 179.5 272.4 124.8 121.4 136.5 192.7 233.9 319.0 251.3 643.7 325.4 204.7 665.7 193.7 260.0 203.5 206.1 593.3 227.7 177.1 175.2 158.2 194.4 608.0 235.0 258.1 988.2 93.7 97.1 117.3 110.1 96.7 115.0 111.0 101.7 114.6 99.3 111.6 101.4 31.5 57.7 50.4 17.3 59.0 117.6 164.6 339.4 103.6 41.9 59.3 46.1 662.2 140.2 139.2 121.4 29.2 334.4 28.0 550.2 365.9 163.7 155.0 64.0 41.6 53.4 144.5 80.6 16.9 166.3 311.1 78.2 167.7 61.5 82.4 72.5 49.6 188.0 238.2 40.4 22.0 319.6 223.8 118.1 85.4 331.9 58.4 107.7 119.2 12.2 129.1 67.1 51.5 14.6 12.5 163.5 333.3 70.7 117.6 78.4 553.4 398.4 104.7 65.0 59.2 61.2 153.0 110.3 74.7 173.0 105.4 336.7 50.8 172.1 416.8 153.4 VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 975.7;Granulosa cells: 1131.8;Kupffer cells: 547.3;Macrophages: 605.6;monocytes: 948.1;Oligodendrocyte precursor cells: 1644.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 20 "dendritic cells: 88.9;monocytes: 240.0" "Cell line enhanced" "Detected in many" "AF22: 300.5;HSkMC: 199.5;hTERT-RPE1: 959.0;RPTEC TERT1: 381.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" 42.0 23.9 18.6 74.9 20.8 32.6 15.6 24.2 23.0 29.4 5.2 11.3 3.8 17.8 1.8 3.8 8.6 30.5 45.0 25.7 27.8 6.5 2.7 34.4 2.3 36.1 19.3 2.1 3.1 2.4 2.1 73.5 31.3 6.8 10.7 0.2 7.6 4.2 3.9 11.2 5.7 48.0 28.9 13.9 7.7 4.8 44.9 2.7 6.6 6.8 1.9 48.3 7.2 42.7 0.2 5.6 300.5 0.1 119.8 81.5 0.1 2.3 6.2 2.1 1.5 3.1 0.2 0.0 45.2 111.5 3.9 0.0 0.4 0.4 1.7 0.1 9.8 2.1 0.0 2.3 5.5 0.1 0.0 199.5 0.1 127.6 1.2 959.0 0.1 0.0 0.0 0.1 64.6 0.0 0.5 0.0 51.1 0.0 10.3 0.0 63.0 0.1 381.0 0.0 3.6 15.5 0.0 0.0 0.2 33.2 0.2 0.5 116.5 90.6 0.5 168.3 179.0 0.0 0.1 0.2 41.8 0.1 16.4 8.3 240.0 0.5 0.5 31.3 0.3 0.2 0.1 0.1 88.9 0.1 0.1 0.0 3.9 0.5 3.5 1.7 0.0 94.0 18.6 20.8 24.2 23.0 25.7 27.8 36.1 19.3 31.3 28.9 44.9 42.7 23.4 19.2 19.8 128.9 5.5 38.6 10.6 14.9 1.2 0.0 1.8 1.9 8.2 44.3 17.5 25.8 0.0 5.9 7.4 0.0 0.0 1.9 3.0 64.4 975.7 29.9 0.0 5.2 1.5 0.7 7.0 348.1 3.6 241.3 12.6 1131.8 16.8 3.6 25.6 0.0 30.7 0.2 0.0 547.3 83.1 2.5 18.6 605.6 44.4 20.6 948.1 0.0 13.4 1644.7 1.5 32.3 1.1 117.8 2.5 2.5 0.0 1.8 16.2 0.0 0.0 11.0 80.6 0.9 1.2 1.1 28.7 11.5 12.7 1.6 0.3 0.9 VIM ENSG00000026025 Vimentin P08670 10 17228241-17237593 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 4879.0;Langerhans cells: 4893.1;Leydig cells: 5013.2;Muller glia cells: 8977.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 18287.8;fHDF/TERT166: 10084.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000080, HPA001762, CAB058687" Enhanced Supported "Intermediate filaments" NA NA 35000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Intermediate filaments" "CAB000080: AB_2304493, CAB058687: AB_2665570, HPA001762: AB_1080568" "unprognostic (1.02e-1)" "unprognostic (2.58e-1)" "unprognostic (2.87e-2)" "prognostic favorable (9.75e-6)" "unprognostic (3.81e-2)" "unprognostic (2.52e-1)" "unprognostic (3.21e-1)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" "unprognostic (2.05e-1)" "unprognostic (9.29e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.87e-3)" "unprognostic (7.32e-2)" "unprognostic (1.82e-1)" "unprognostic (9.47e-3)" 3467.6 423.1 349.3 610.6 369.5 1455.5 2362.8 289.1 527.4 1816.3 568.1 923.2 218.4 1226.5 400.0 451.5 1458.7 960.2 1364.3 337.5 404.6 473.6 192.8 1133.2 806.2 667.4 328.2 3690.8 370.0 224.8 574.5 1030.0 443.7 570.0 400.8 731.0 628.5 551.8 363.7 1126.8 674.7 1109.3 414.6 819.9 522.8 251.7 472.7 412.2 1391.1 555.8 744.7 983.5 1366.6 425.5 21.2 1119.0 1981.0 3180.7 6407.4 18287.8 3.0 5238.5 3458.9 3859.2 3421.5 8.5 70.4 2.9 273.2 10084.4 1804.7 8.4 283.8 147.0 3734.1 3567.5 387.2 563.2 523.5 0.3 1967.3 301.1 222.8 6746.8 6.5 5712.0 3213.4 9020.8 6366.3 372.4 889.3 1575.4 6939.5 4.5 736.6 911.2 632.4 1.4 1394.0 564.8 2745.9 95.7 3925.3 0.8 8.1 946.6 1.4 6.9 5447.5 1133.1 8.6 341.8 5459.0 3819.8 1644.5 3244.7 6311.5 1754.4 953.7 130.4 5775.4 28.9 3726.3 667.8 751.8 215.2 219.5 469.3 278.7 176.3 357.0 285.0 866.0 117.5 217.1 217.2 409.3 99.2 471.2 342.3 481.5 615.4 349.3 369.5 289.1 527.4 337.5 404.6 667.4 328.2 443.7 414.6 472.7 425.5 3211.7 157.0 349.4 53.5 605.8 725.8 21.6 361.2 58.1 74.2 108.8 539.1 109.5 94.4 157.3 108.5 50.1 22.1 1110.1 9.1 5.9 198.8 58.1 922.9 2314.1 2923.2 309.1 236.5 0.4 569.0 45.8 3443.0 101.4 693.7 2776.4 4879.0 2195.6 19.2 3541.4 33.7 0.3 1.8 16.2 2841.2 4893.1 131.6 5013.2 3177.8 3082.5 85.3 3893.1 8977.0 259.5 1.0 0.4 525.9 1.5 2336.6 2097.2 79.5 3.1 181.6 90.7 284.1 1420.0 3171.9 3714.2 55.1 27.5 39.4 473.0 52.7 1566.3 1791.1 6.2 28.9 VNN1 Tiff66 ENSG00000112299 "Vanin 1" O95497 6 132680849-132714055 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "gallbladder: 89.2;intestine: 136.3;liver: 218.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 50.1;Ductal cells: 244.2;Hepatocytes: 70.6;Pancreatic endocrine cells: 98.0;Proximal enterocytes: 61.7" "Cancer enhanced" "Detected in many" "liver cancer: 41.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "classical monocyte: 13.7;non-classical monocyte: 11.9" "Group enriched" "Detected in many" 80 "dendritic cells: 5.0;granulocytes: 8.5;monocytes: 13.7" "Cell line enhanced" "Detected in some" "A-431: 2.5;CAPAN-2: 2.5;EFO-21: 8.7;HBEC3-KT: 2.3;LHCN-M2: 2.5" "Region enhanced" "Detected in single" "white matter: 2.4" "Not detected" "Not detected" "HPA046103, HPA064145" Approved Approved Vesicles "Intracellular and membrane" NA NA 980000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA046103: , HPA064145: AB_2685197" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (9.95e-2)" "unprognostic (1.35e-3)" "unprognostic (6.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (4.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (2.26e-2)" "unprognostic (4.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.34e-1)" 2.7 0.6 0.3 3.1 0.6 9.4 1.1 0.5 1.5 1.0 0.0 6.2 136.3 8.9 0.2 0.6 2.6 89.2 0.6 0.2 0.3 21.7 218.7 4.7 2.5 0.6 0.3 0.3 1.4 0.1 0.1 2.7 1.2 0.3 1.8 1.0 2.3 0.2 0.3 0.9 79.5 0.9 0.2 10.1 1.5 0.5 0.5 0.6 0.4 1.1 2.5 1.6 0.7 0.9 2.5 0.0 0.3 0.1 0.0 0.7 0.5 0.2 0.2 0.0 0.0 0.0 2.5 0.1 8.7 0.0 0.4 0.0 0.0 2.3 0.6 0.0 0.0 0.1 0.1 1.4 1.3 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.1 1.1 0.5 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.6 0.0 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.3 3.0 13.7 0.0 0.0 8.0 0.0 0.0 0.0 0.0 5.0 0.1 0.0 0.0 8.5 0.0 11.9 0.2 0.0 3.8 0.3 0.6 0.5 1.5 0.2 0.3 0.6 0.3 1.2 0.2 0.5 0.9 0.0 0.0 3.0 0.0 0.3 1.3 0.2 14.9 0.0 0.0 1.2 0.4 0.2 50.1 11.4 1.8 0.0 0.1 0.2 12.5 0.0 244.2 0.0 7.6 4.1 0.2 0.0 0.0 0.0 19.4 0.1 0.3 4.6 39.6 0.0 0.0 1.1 70.6 18.1 0.0 0.0 11.2 22.4 12.0 3.9 0.0 0.0 23.1 0.0 0.0 17.6 0.0 0.0 0.0 0.0 98.0 1.6 0.0 0.5 6.6 61.7 21.9 16.0 0.0 0.0 0.4 1.1 0.1 0.0 0.1 0.1 0.1 0.5 0.0 2.0 14.7 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 WDR49 FLJ33620 ENSG00000174776 "WD repeat domain 49" Q8IV35 3 167478684-167653983 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 31.3;choroid plexus: 29.3;fallopian tube: 10.0" "Group enriched" "Detected in some" 5 "Astrocytes: 79.0;Endometrial ciliated cells: 43.4;Respiratory ciliated cells: 47.7" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 2.7;myeloid DC: 2.2;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 24 "dendritic cells: 2.9;monocytes: 2.7" "Cell line enhanced" "Detected in some" "AF22: 2.7;NTERA-2: 3.0;THP-1: 14.5;U-937: 7.8" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 9.5" "HPA036225, HPA036226" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nuclear bodies" Cytosol "HPA036225: AB_10696652, HPA036226: AB_2675007" "unprognostic (1.68e-3)" "unprognostic (1.24e-3)" "unprognostic (2.48e-2)" "unprognostic (1.96e-1)" "unprognostic (5.67e-2)" "unprognostic (5.11e-3)" "unprognostic (1.66e-1)" "unprognostic (6.02e-2)" "unprognostic (9.28e-3)" "unprognostic (1.34e-1)" "unprognostic (4.60e-9)" "unprognostic (1.79e-4)" "unprognostic (3.50e-2)" "unprognostic (3.57e-2)" "unprognostic (2.07e-1)" 0.1 0.1 10.2 0.4 8.2 2.0 0.1 16.6 3.4 0.3 29.3 0.1 2.0 0.4 0.0 0.9 10.0 0.2 2.1 7.0 15.6 0.3 0.0 1.9 0.3 30.1 27.0 0.1 0.3 0.0 0.5 0.0 23.8 0.2 0.1 0.0 0.2 0.0 0.0 0.1 4.6 0.1 31.3 0.4 0.2 0.6 15.5 0.4 0.0 0.2 0.3 0.2 0.2 23.4 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.8 0.0 0.0 2.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.5 10.2 8.2 16.6 3.4 7.0 15.6 30.1 27.0 23.8 31.3 15.5 23.4 0.2 0.0 0.6 79.0 0.1 0.0 0.9 1.7 9.1 0.0 0.1 0.1 1.1 0.0 10.9 0.0 0.0 0.0 1.6 0.1 0.0 0.1 2.4 43.4 0.3 0.2 0.0 1.7 4.5 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 4.1 1.6 2.5 0.8 0.0 1.8 0.0 0.0 4.0 0.0 0.0 2.5 3.0 0.0 0.0 0.0 0.1 0.4 3.3 0.0 47.7 0.0 6.6 0.3 0.6 0.1 0.2 1.0 0.1 0.0 0.1 0.0 0.2 0.8 ZCCHC24 "C10orf56, FLJ90798, Z3CXXC8" ENSG00000165424 "Zinc finger CCHC-type containing 24" Q8N2G6 10 79382325-79445624 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 148.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 66.0;Hepatic stellate cells: 64.2;Hepatocytes: 59.2;Leydig cells: 68.6;Oligodendrocyte precursor cells: 184.5;Oligodendrocytes: 130.6;Peritubular cells: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 135.0;ASC TERT1: 115.1;BJ hTERT+: 91.6;HSkMC: 120.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038348 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria Nucleoplasm "HPA038348: AB_10669538" "unprognostic (3.47e-3)" "unprognostic (8.70e-3)" "unprognostic (3.35e-1)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (7.28e-2)" "unprognostic (2.17e-2)" "unprognostic (2.25e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (3.76e-4)" "unprognostic (4.77e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (5.35e-6)" "unprognostic (1.84e-2)" "unprognostic (5.52e-2)" "unprognostic (2.85e-2)" "unprognostic (2.95e-3)" 40.4 11.9 119.7 13.8 147.7 2.6 32.5 112.0 109.7 42.3 44.8 67.7 6.2 42.8 8.9 14.0 34.1 23.8 35.7 89.4 101.0 8.7 33.1 22.7 7.5 134.9 145.8 26.4 8.4 4.0 9.4 16.1 120.3 32.2 8.9 3.7 12.0 27.2 58.0 13.7 18.2 36.1 119.7 10.9 25.5 8.9 136.8 2.7 18.4 26.5 4.3 43.2 22.9 148.0 3.3 3.1 10.4 9.0 135.0 115.1 2.5 24.6 91.6 14.2 16.5 2.6 0.1 0.1 13.1 49.5 5.0 0.3 1.7 0.6 11.9 6.2 6.5 1.3 7.2 3.1 35.1 3.8 2.0 120.5 1.3 12.8 3.5 42.1 2.9 0.9 4.8 5.3 12.3 1.1 0.1 14.9 2.5 0.6 30.1 0.6 12.3 2.2 1.7 4.0 0.3 12.9 7.7 0.9 31.5 9.7 3.5 7.0 2.0 13.6 12.4 37.4 8.5 9.2 6.5 0.1 27.9 4.9 49.4 0.0 0.6 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.1 0.1 119.7 147.7 112.0 109.7 89.4 101.0 134.9 145.8 120.3 119.7 136.8 148.0 36.2 0.0 2.6 29.0 1.4 7.6 1.4 1.5 1.8 0.1 5.6 5.7 20.2 5.7 1.2 0.0 0.0 0.6 4.5 0.3 0.0 0.8 2.0 2.3 66.0 29.5 0.0 4.4 0.3 0.8 0.9 40.9 5.1 2.6 1.3 4.1 64.2 59.2 10.7 0.0 0.5 0.4 0.0 17.1 14.5 4.8 68.6 7.4 16.0 30.0 5.6 16.7 1.0 184.5 130.6 0.9 0.1 65.5 5.0 2.9 0.0 1.8 1.2 1.1 13.1 38.7 24.0 0.7 1.7 1.4 4.5 1.5 3.6 8.9 0.1 1.3 ZDHHC20 "DHHC20, FLJ25952" ENSG00000180776 "Zinc finger DHHC-type palmitoyltransferase 20" Q5W0Z9 13 21372571-21459370 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 434.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014483, HPA014702" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA014483: AB_1859000, HPA014702: AB_1859001" "unprognostic (1.31e-1)" "unprognostic (2.16e-3)" "unprognostic (7.31e-3)" "unprognostic (8.89e-2)" "unprognostic (3.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-1)" "unprognostic (1.24e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (6.55e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.76e-2)" "unprognostic (7.65e-2)" "unprognostic (6.15e-2)" "unprognostic (1.13e-2)" 10.9 9.2 15.2 17.6 52.9 30.0 11.5 51.8 23.3 16.2 0.0 16.9 19.3 13.8 9.6 30.2 10.9 17.1 7.9 12.0 27.0 6.7 9.8 17.0 18.0 70.8 40.7 9.7 9.0 8.9 4.4 18.8 60.3 15.1 16.1 5.6 8.5 12.2 4.0 22.1 19.0 15.2 35.1 16.1 39.5 31.7 40.7 22.6 16.4 9.4 19.5 22.9 9.3 95.0 32.9 16.4 27.7 18.1 24.5 26.7 68.3 35.6 36.3 23.3 20.6 33.8 102.5 34.8 19.3 44.7 23.8 52.7 30.5 26.5 44.8 40.0 20.4 61.8 11.7 19.6 14.1 43.3 25.8 24.2 19.4 23.6 16.2 30.0 37.6 45.9 17.3 14.9 35.3 27.2 62.0 17.2 22.9 87.3 18.0 49.8 49.1 12.7 28.9 59.7 25.2 11.4 46.0 28.7 19.3 28.6 27.0 21.8 62.6 25.0 24.0 41.7 27.4 15.6 19.9 37.7 18.2 23.6 73.1 12.6 16.2 3.8 10.1 14.9 9.3 4.6 8.7 8.7 8.4 3.4 8.1 8.4 3.0 11.2 13.8 4.1 10.4 13.5 15.2 52.9 51.8 23.3 12.0 27.0 70.8 40.7 60.3 35.1 40.7 95.0 27.6 51.3 31.5 29.0 19.9 1.0 7.8 1.4 18.2 7.4 21.9 13.7 7.4 14.3 20.7 11.0 8.4 20.7 34.7 35.5 0.0 8.5 91.3 23.4 25.2 25.7 24.0 8.4 69.1 12.2 20.9 13.6 53.0 34.5 14.0 16.1 20.0 20.8 21.7 18.5 80.0 29.1 2.0 92.5 3.2 81.2 15.5 49.0 1.8 46.9 48.4 3.7 30.9 54.8 434.3 22.8 25.5 10.9 18.1 14.5 30.3 6.3 11.7 9.5 19.7 12.7 11.6 10.4 14.1 28.1 1.6 44.6 28.4 9.7 25.1 25.6