Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AC004080.3 ENSG00000257184 "HOXA10-HOXA9 readthrough" 7 27163535-27180013 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BJ: 1.3" "Region enriched" "Detected in single" 165 "spinal cord: 16.4" NA NA "Cluster 10: BJ & FHDF - ECM organization" "unprognostic (4.27e-1)" "unprognostic (4.63e-1)" "unprognostic (4.49e-1)" 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 1.3 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC055839.2 ENSG00000286190 "Uncharacterized LOC728392" 17 5499427-5501006 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 317.6;choroid plexus: 86.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 4.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.8" "Cell line enhanced" "Detected in many" "AF22: 42.8;BJ: 46.1;hTERT-RPE1: 41.9" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" 5.8 65.9 175.1 9.0 192.7 4.6 2.4 102.1 194.2 9.8 86.1 3.6 4.6 15.0 11.7 0.9 18.0 6.0 2.6 180.3 301.0 2.3 0.7 4.1 8.6 181.4 210.3 30.8 6.8 12.1 7.5 200.3 9.9 2.8 15.2 2.4 18.5 2.9 13.9 4.5 6.6 218.2 11.7 7.4 8.3 317.6 9.9 2.2 1.7 3.8 2.8 231.2 2.3 0.5 42.8 10.6 13.9 7.3 1.7 46.1 29.6 17.3 11.0 0.0 0.4 0.6 9.2 17.4 7.6 1.6 4.1 1.4 9.0 19.5 6.9 0.1 2.2 1.9 4.3 0.0 0.4 6.0 3.6 19.8 1.0 41.9 1.1 3.0 3.2 8.8 11.0 0.8 1.8 2.1 4.9 0.0 0.4 2.8 2.7 7.2 0.0 0.6 15.7 25.7 0.0 0.1 0.2 15.9 0.0 0.0 2.5 6.8 6.1 5.2 1.2 22.9 5.2 0.3 20.9 0.0 0.5 4.8 0.1 0.0 0.3 0.1 0.0 0.8 0.2 0.2 0.1 0.0 0.3 0.1 1.0 0.2 0.0 0.0 0.7 0.1 175.1 192.7 102.1 194.2 180.3 301.0 181.4 210.3 200.3 218.2 317.6 231.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC058822.1 ENSG00000282278 "Novel FIP1L1-PDGFRA fusion protein" 4 53377839-54295272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.7;BJ hTERT+: 10.2;fHDF/TERT166: 17.2;HSkMC: 9.8;U-138 MG: 5.4;U-2197: 7.7" HPA058202 Supported Nucleoplasm NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "HPA058202: AB_2683636" 0.9 0.0 1.0 2.0 1.5 0.0 0.0 0.4 1.7 0.3 1.5 0.4 0.5 0.3 0.0 1.3 0.1 0.4 1.6 0.9 0.7 0.3 0.3 0.8 0.0 1.6 0.7 1.2 0.8 0.0 0.0 1.2 1.3 0.2 0.0 0.8 0.0 0.0 0.3 0.0 1.0 0.9 0.5 0.2 0.8 2.2 0.5 0.1 0.0 2.0 0.1 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.8 4.7 0.0 1.5 10.2 0.0 0.1 0.9 0.0 0.0 0.0 17.2 0.0 0.0 1.5 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 9.8 0.0 3.8 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.1 5.4 0.1 7.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 1.5 0.4 1.7 0.9 0.7 1.6 0.7 1.3 0.5 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ACKR4 "CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1" ENSG00000129048 "Atypical chemokine receptor 4" Q9NPB9 3 132597270-132618967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Fibroblasts: 21.4;Proximal enterocytes: 19.1;Respiratory ciliated cells: 15.7" "Cancer enhanced" "Detected in many" "stomach cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "BJ hTERT+: 285.1" "Group enriched" "Detected in some" 7 "cerebellum: 4.7;pons and medulla: 1.5" "Low region specificity" "Detected in all" HPA054926 Approved Vesicles,Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Mitochondria" "HPA054926: " "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.62e-2)" "unprognostic (8.27e-2)" "unprognostic (5.17e-2)" "unprognostic (4.55e-3)" "unprognostic (8.93e-2)" "unprognostic (2.26e-1)" "unprognostic (4.85e-2)" "unprognostic (4.20e-3)" "unprognostic (1.03e-3)" "unprognostic (2.69e-3)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" 11.1 1.4 0.6 1.0 0.2 0.8 5.5 0.3 0.3 0.7 0.9 1.9 15.8 3.7 1.7 1.4 2.0 6.5 5.7 0.4 0.0 1.1 1.0 8.0 2.1 0.3 0.5 1.0 2.6 0.0 6.7 0.2 0.3 0.5 1.3 0.6 7.1 1.9 0.5 8.9 13.0 2.2 0.3 1.6 10.2 0.4 0.1 0.5 1.4 1.0 1.6 4.6 1.1 0.2 0.2 0.0 0.2 0.2 19.9 10.7 0.1 47.7 285.1 2.8 7.9 0.2 0.4 3.3 0.0 29.9 0.2 0.1 0.0 0.0 1.8 1.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 1.3 0.0 0.0 4.9 0.1 0.2 0.6 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 1.0 0.1 0.1 0.2 0.0 0.5 0.1 0.7 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.3 0.4 0.0 0.3 0.5 0.3 0.3 0.1 0.2 1.6 38.5 1.1 0.7 0.1 6.5 0.6 1.3 0.0 1.6 0.3 0.3 0.7 1.5 2.3 5.5 6.2 0.2 0.1 1.1 0.0 0.2 2.9 2.9 0.6 3.9 0.0 0.0 0.6 12.1 0.1 21.4 10.7 0.6 0.0 0.7 9.7 0.2 0.4 1.7 0.5 0.8 0.0 0.3 5.1 0.4 2.1 0.3 1.8 1.9 6.8 0.9 0.0 0.0 0.3 5.1 0.1 2.6 0.5 0.4 19.1 3.0 15.7 3.4 0.0 1.3 2.6 0.1 0.1 0.6 6.5 0.3 0.5 12.5 3.7 1.2 ACOX3 ENSG00000087008 "Acyl-CoA oxidase 3, pristanoyl" O15254 4 8366282-8440723 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035840, HPA035841" Uncertain Supported Peroxisomes NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Peroxisomes "HPA035840: AB_10696514, HPA035841: AB_10671940" "unprognostic (3.07e-2)" "unprognostic (5.51e-2)" "unprognostic (1.12e-1)" "prognostic favorable (2.16e-4)" "unprognostic (5.52e-2)" "unprognostic (1.81e-3)" "unprognostic (2.21e-1)" "unprognostic (3.37e-2)" "unprognostic (2.27e-1)" "unprognostic (4.43e-2)" "unprognostic (4.81e-1)" "unprognostic (1.39e-1)" "unprognostic (1.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.84e-1)" "unprognostic (1.69e-1)" "unprognostic (2.65e-1)" 7.7 8.8 5.8 6.4 5.2 4.4 12.2 3.8 7.2 9.5 5.9 8.4 8.9 5.6 4.3 26.6 6.6 5.9 16.2 5.3 4.9 6.5 14.9 7.2 6.6 5.9 4.6 7.5 12.0 7.1 4.5 8.4 4.7 10.5 6.3 3.8 15.4 8.4 6.4 12.5 8.9 11.4 4.2 5.3 10.1 2.9 5.0 4.6 8.5 5.6 8.5 10.1 13.7 7.1 8.9 9.6 10.5 14.1 11.0 18.7 17.2 11.1 15.1 18.5 16.1 4.8 11.7 11.9 11.7 22.8 25.0 5.4 4.6 14.4 14.3 4.1 4.5 5.2 8.2 14.8 18.3 10.7 9.4 18.9 12.1 16.7 6.5 13.3 22.1 13.1 7.0 10.6 16.1 8.2 11.4 15.6 5.9 11.3 16.4 11.8 17.3 14.3 11.2 12.4 5.1 11.7 14.2 7.2 7.3 8.6 7.2 14.9 21.7 18.2 5.9 7.5 11.8 7.9 5.6 5.4 23.2 13.1 11.8 0.1 13.2 3.3 6.1 15.2 6.3 5.4 7.1 7.8 17.8 4.9 6.5 6.7 3.1 9.5 14.4 21.4 10.4 9.4 5.8 5.2 3.8 7.2 5.3 4.9 5.9 4.6 4.7 4.2 5.0 7.1 6.2 6.4 5.9 14.7 4.8 4.5 7.6 12.3 8.6 8.2 11.6 7.6 9.4 10.0 9.8 11.0 33.3 23.9 7.7 10.9 3.9 17.3 4.4 13.1 4.2 5.6 1.8 3.0 13.2 13.7 9.3 6.6 10.2 10.0 0.0 21.7 4.6 14.2 10.2 1.7 14.2 4.9 14.2 4.1 4.4 3.3 6.8 5.3 5.4 6.5 7.6 3.8 2.1 12.5 14.5 16.9 7.4 11.3 5.6 9.1 18.3 8.2 11.2 18.6 0.0 3.8 6.9 2.4 2.3 14.1 5.8 74.6 6.0 6.0 7.5 11.4 ACTG1 "ACTG, DFNA20, DFNA26" ENSG00000184009 "Actin gamma 1" P63261 17 81509413-81523847 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, Mental retardation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 9107.1;Exocrine glandular cells: 8305.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041264, HPA041271" Approved NA NA 4900000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (3.95e-2)" "unprognostic (3.38e-1)" "prognostic favorable (2.41e-4)" "unprognostic (2.73e-2)" "unprognostic (1.16e-2)" "unprognostic (1.03e-1)" "unprognostic (1.29e-3)" "unprognostic (2.45e-3)" "unprognostic (3.47e-2)" "unprognostic (3.06e-2)" "unprognostic (4.54e-2)" "unprognostic (9.03e-2)" "unprognostic (1.51e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-2)" "unprognostic (1.25e-1)" "unprognostic (3.40e-3)" 1548.5 950.4 523.3 1325.4 549.3 1130.2 1158.2 582.8 628.6 1634.2 506.2 1258.5 994.5 1629.9 558.1 2422.2 1315.8 1179.5 666.3 548.5 677.3 905.8 762.8 1516.1 1696.9 652.8 592.5 2046.6 1693.4 608.2 824.5 922.4 629.8 723.8 662.3 293.9 1291.3 643.0 358.4 1455.8 1026.3 739.2 589.8 1034.8 1385.5 438.5 611.8 1347.8 1252.2 270.9 1292.7 1540.3 1571.3 709.7 3652.9 4010.4 4601.5 2275.7 813.0 2758.2 1601.3 4193.6 3154.7 3546.5 2675.5 3699.5 1690.3 2114.0 2566.1 4263.6 2867.3 2049.5 1722.7 3395.6 1727.7 3745.8 2549.8 1724.3 1784.6 3515.1 2165.8 1909.2 2003.4 3599.7 1366.0 3586.4 938.0 4516.4 5237.2 1343.4 331.2 2723.2 3288.0 2677.4 6305.5 2235.8 1970.8 2272.7 2122.3 3520.6 1537.3 1716.3 3385.4 2838.3 1234.4 1284.1 4804.4 969.0 5127.0 1530.7 2192.3 1908.9 5402.3 4755.5 1993.3 2802.6 7012.2 908.3 791.7 1505.4 3808.4 1910.5 2940.1 4240.1 1897.3 3013.3 2108.9 2333.9 2026.4 1297.8 1892.2 2024.3 3012.5 939.2 1391.8 1827.7 1532.7 1355.2 2939.2 1616.5 2980.5 5301.8 523.3 549.3 582.8 628.6 548.5 677.3 652.8 592.5 629.8 589.8 611.8 709.7 1602.0 974.4 558.2 107.1 1285.4 5276.1 9107.1 3827.4 2541.1 493.3 1477.5 1943.4 233.6 825.0 1924.3 1140.3 244.0 2002.6 1886.0 2460.0 1058.5 4368.6 293.0 1028.0 1501.0 1664.2 1914.5 567.0 59.0 8305.0 4361.7 1595.3 2440.4 1433.3 588.7 3067.7 1031.6 517.1 3219.5 267.5 65.7 2206.9 1957.2 1426.0 1807.7 258.5 1718.6 1840.3 1398.1 70.3 4004.3 3402.9 1971.2 78.4 111.9 7194.7 2426.5 1363.9 1369.6 3987.9 1673.2 566.6 950.0 571.1 1360.8 873.0 2277.1 756.5 995.7 3085.9 5371.9 2827.2 1823.7 2394.4 2187.5 6279.2 ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 524.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 364.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 210000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004303: AB_626633, HPA006035: AB_1078095" "unprognostic (4.40e-2)" "unprognostic (1.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (6.19e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (3.62e-1)" "unprognostic (3.23e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.08e-10)" "unprognostic (2.87e-2)" "unprognostic (2.00e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (8.00e-4)" 117.4 40.7 27.3 149.5 55.8 149.3 103.5 0.1 32.0 118.4 20.1 449.8 49.8 313.1 60.3 154.4 152.1 143.9 121.4 29.7 14.7 46.7 61.8 100.0 47.5 24.5 11.0 61.8 46.8 9.1 27.3 96.1 7.3 174.3 109.0 28.2 116.4 295.1 21.7 59.3 106.9 524.5 4.2 55.9 171.7 21.2 32.9 32.6 35.0 13.3 50.7 305.9 83.3 28.8 871.9 262.3 158.6 121.4 275.2 180.5 592.4 749.3 712.0 770.0 571.1 211.8 196.6 0.7 256.5 744.7 310.4 370.9 126.8 790.3 965.2 4.6 38.5 118.2 133.5 179.0 494.0 85.4 14.3 231.7 152.1 479.8 540.3 551.6 428.6 48.2 56.9 1.4 612.0 246.9 10.1 181.1 124.7 217.9 198.1 59.3 294.1 32.6 292.0 225.6 57.0 68.7 649.9 96.8 177.1 474.8 146.0 170.9 546.0 1085.2 432.8 126.9 662.5 113.8 47.8 3.9 314.4 115.7 584.4 64.6 67.5 137.1 5.7 28.8 7.1 0.1 22.7 12.4 45.5 0.2 103.9 92.2 364.2 4.5 8.9 2.0 9.6 89.2 27.3 55.8 0.1 32.0 29.7 14.7 24.5 11.0 7.3 4.2 32.9 28.8 44.7 38.5 25.1 19.6 4.0 119.3 154.9 137.4 82.0 74.7 88.6 157.6 60.3 51.5 36.0 42.3 246.0 155.3 3.0 17.2 3.9 186.8 34.0 65.8 112.8 135.5 38.5 21.9 102.7 144.9 351.8 88.9 34.1 90.2 7.6 15.9 129.5 96.6 79.5 18.5 29.7 57.3 59.0 100.9 82.1 10.7 35.8 96.4 30.2 34.7 105.1 6.0 4.1 9.0 4.3 203.7 28.0 245.6 0.6 132.6 2.4 15.3 47.8 80.8 177.5 30.0 270.6 19.4 18.4 51.8 59.8 66.9 22.7 20.9 47.0 67.1 ADAM19 MLTNB ENSG00000135074 "ADAM metallopeptidase domain 19" Q9H013 5 157395534-157575775 "Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 56.7;Cone photoreceptor cells: 62.6;Extravillous trophoblasts: 81.8;Langerhans cells: 49.3;monocytes: 83.5;Plasma cells: 53.8;Rod photoreceptor cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 128.3;eosinophil: 139.9;memory B-cell: 50.8;naive B-cell: 53.5;neutrophil: 70.5;plasmacytoid DC: 66.8" "Group enriched" "Detected in many" 5 "B-cells: 53.5;dendritic cells: 66.8;granulocytes: 139.9" "Cell line enhanced" "Detected in many" "HDLM-2: 109.7;U-251 MG: 206.5" "Low region specificity" "Detected in all" HPA055537 Approved Vesicles NA NA 17000 "Cluster 2: Granulocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Vesicles "HPA055537: AB_2797253" "unprognostic (4.71e-1)" "unprognostic (1.01e-1)" "unprognostic (1.77e-1)" "unprognostic (4.64e-2)" "unprognostic (1.81e-3)" "unprognostic (2.63e-1)" "unprognostic (2.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.76e-2)" "unprognostic (2.80e-1)" "unprognostic (1.42e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.90e-12)" "unprognostic (1.44e-1)" "unprognostic (4.38e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-2)" 4.9 3.6 2.6 24.0 3.3 7.7 2.7 5.3 4.6 4.9 0.4 22.8 5.8 8.0 2.6 5.1 7.4 8.9 24.7 3.1 3.8 2.1 9.6 13.2 29.0 5.1 4.5 3.5 0.9 0.1 1.8 13.1 4.7 7.6 6.7 22.6 1.9 6.3 6.5 1.4 18.7 16.3 3.1 22.6 9.6 1.6 4.5 7.4 4.2 2.8 30.2 18.8 5.2 3.9 38.8 6.0 11.5 0.1 0.8 0.7 73.7 45.0 16.0 27.5 20.5 19.9 30.7 19.9 2.4 23.4 5.7 32.4 1.8 2.9 24.9 109.7 1.1 0.1 3.3 2.7 6.5 0.1 0.0 5.2 0.1 21.5 4.3 32.7 31.5 0.0 5.7 2.8 59.4 0.0 0.0 0.1 12.3 0.0 19.3 0.6 65.9 16.8 2.9 0.6 5.2 3.5 0.0 15.9 2.3 45.3 0.2 0.6 48.7 29.6 31.7 6.8 206.5 11.8 0.4 69.6 6.7 0.1 13.5 128.3 13.1 139.9 1.5 1.2 3.5 50.8 14.4 3.3 4.2 53.5 0.4 0.4 70.5 0.4 0.1 66.8 16.6 9.2 2.6 3.3 5.3 4.6 3.1 3.8 5.1 4.5 4.7 3.1 4.5 3.9 1.5 6.4 0.6 2.0 56.7 2.2 0.1 1.2 0.0 37.7 0.5 0.4 5.6 0.0 0.7 3.7 62.6 1.1 22.0 0.1 0.0 0.5 4.1 0.5 6.8 5.6 0.0 1.7 24.2 1.5 81.8 6.5 0.5 0.2 0.0 0.3 4.2 7.5 1.7 15.2 21.2 0.1 0.0 9.0 49.3 1.3 5.6 12.4 1.8 10.3 83.5 2.4 1.0 13.0 28.7 2.2 0.1 7.9 53.8 0.2 0.0 0.1 0.1 43.9 6.6 12.3 13.3 0.0 1.1 2.5 1.4 8.3 24.0 1.7 0.3 0.2 ADAMTS6 ADAM-TS6 ENSG00000049192 "ADAM metallopeptidase with thrombospondin type 1 motif 6" Q9UKP5 5 65148738-65481920 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.6;Inhibitory neurons: 63.6;Microglial cells: 31.9;Oligodendrocyte precursor cells: 139.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.1;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Cell line enhanced" "Detected in many" "BJ: 12.6;HBF TERT88: 13.4;hTEC/SVTERT24-B: 12.6;hTERT-HME1: 14.9;TIME: 14.5;U-2197: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043441 Enhanced "Secreted to extracellular matrix" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043441: AB_2678484" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (2.70e-3)" "unprognostic (4.33e-2)" "unprognostic (1.03e-2)" "unprognostic (2.39e-2)" "unprognostic (8.24e-2)" "unprognostic (1.65e-2)" "unprognostic (4.77e-2)" "unprognostic (8.04e-2)" "unprognostic (1.56e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-6)" "unprognostic (3.23e-5)" "unprognostic (2.09e-1)" "unprognostic (3.02e-4)" "unprognostic (4.18e-3)" 0.5 0.1 0.2 0.6 0.2 0.0 0.3 0.2 0.3 0.3 0.5 0.3 0.1 1.1 0.7 0.2 0.6 1.4 0.3 0.2 0.6 0.2 0.0 0.5 0.4 0.3 0.4 0.3 0.0 0.0 0.1 1.9 0.3 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.6 0.6 0.3 0.7 0.3 0.5 0.3 0.2 0.1 0.1 0.3 0.7 0.3 0.2 2.7 0.0 0.6 0.6 0.0 2.0 0.0 12.6 7.4 7.7 9.0 0.0 0.3 0.0 0.1 4.8 5.3 0.5 0.1 2.4 13.4 2.0 0.0 0.2 5.1 0.3 0.4 0.0 0.7 0.9 0.0 12.6 14.9 3.7 6.9 1.3 0.0 0.0 4.8 0.0 0.7 0.0 0.1 0.3 0.1 0.4 2.6 0.0 0.0 0.0 0.3 0.5 0.2 0.0 0.0 1.6 0.0 0.1 14.5 3.0 4.5 16.2 10.2 0.1 0.0 0.0 3.4 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.4 2.1 0.1 0.2 0.0 1.3 0.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.6 0.3 0.4 0.3 0.3 0.3 0.2 11.3 0.0 0.0 4.9 16.1 0.3 0.0 0.6 0.6 13.9 0.3 0.5 1.8 1.5 0.1 3.7 0.0 34.6 3.2 0.2 0.0 1.4 15.2 8.5 7.4 13.3 0.0 0.0 16.7 0.0 4.7 5.5 0.0 25.7 1.3 18.7 8.9 0.3 2.4 0.0 63.6 0.5 2.0 0.3 1.0 8.0 12.2 3.2 0.0 31.9 0.3 17.4 1.0 139.7 2.1 2.6 0.0 18.0 2.5 0.1 0.1 1.0 0.1 1.1 6.6 5.1 10.5 6.1 8.9 0.3 0.0 14.2 5.1 2.2 0.6 0.0 ADRA1D "ADRA1, ADRA1A, ADRA1R" ENSG00000171873 "Adrenoceptor alpha 1D" P25100 20 4220630-4249287 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.6;cervix: 7.2" "Cell type enhanced" "Detected in some" "Endothelial cells: 1.2;Excitatory neurons: 2.1;Inhibitory neurons: 2.4;Oligodendrocyte precursor cells: 1.0;Smooth muscle cells: 2.4" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.7;BJ: 7.5;CAPAN-2: 3.3;fHDF/TERT166: 4.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038789 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA038789: AB_10673475" "unprognostic (5.37e-2)" "unprognostic (4.65e-1)" "unprognostic (8.73e-2)" "unprognostic (7.75e-11)" "unprognostic (7.83e-3)" "unprognostic (1.54e-2)" "unprognostic (7.62e-2)" "unprognostic (7.82e-4)" "unprognostic (4.41e-3)" "unprognostic (8.37e-2)" "unprognostic (6.09e-2)" "unprognostic (7.24e-3)" "unprognostic (7.71e-7)" "unprognostic (5.21e-3)" "unprognostic (2.76e-1)" "unprognostic (6.01e-3)" "unprognostic (3.32e-5)" 1.2 0.4 5.0 0.0 0.6 0.0 0.8 0.3 4.8 7.2 0.0 2.0 0.0 3.5 0.3 0.2 2.0 0.2 0.3 7.5 4.2 0.3 0.1 2.3 0.0 2.7 4.9 0.6 0.3 0.2 0.0 0.1 2.4 3.4 0.1 0.0 0.2 1.7 0.5 0.4 0.2 0.3 1.3 1.4 1.6 0.7 9.6 0.0 0.8 0.4 0.0 2.4 2.9 1.1 0.0 1.7 0.1 0.0 0.0 0.0 0.0 7.5 1.3 0.4 0.1 0.3 3.3 0.0 0.0 4.4 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.6 0.3 4.8 7.5 4.2 2.7 4.9 2.4 1.3 9.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 2.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.1 AFAP1 "AFAP, AFAP-110" ENSG00000196526 "Actin filament associated protein 1" Q8N556 4 7758714-7939926 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 170.5;Extravillous trophoblasts: 116.3;Inhibitory neurons: 117.2;Late spermatids: 373.8;Oligodendrocyte precursor cells: 125.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.9" "Group enriched" "Detected in many" 5 "granulocytes: 2.9;T-cells: 1.2" "Cell line enhanced" "Detected in many" "TIME: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015642, CAB024712" Enhanced Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" "Focal adhesion sites" "CAB024712: , HPA015642: AB_1844632" "unprognostic (1.12e-1)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (7.29e-2)" "unprognostic (2.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.00e-1)" "unprognostic (3.39e-2)" "unprognostic (3.40e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.44e-2)" 12.6 3.1 7.0 8.7 5.8 0.7 9.7 4.5 6.9 8.7 2.9 17.6 5.6 15.4 2.0 11.0 8.5 9.4 10.8 5.8 4.5 4.9 1.2 8.5 4.4 3.7 2.7 7.1 3.8 14.7 7.9 12.6 2.8 7.7 9.8 3.4 8.6 10.2 3.5 5.3 7.7 15.4 3.4 4.0 6.7 22.0 3.5 3.1 7.4 2.4 4.8 14.2 8.3 3.5 31.9 23.2 16.2 12.9 15.4 27.8 21.3 46.4 68.1 43.6 40.0 7.4 7.2 0.1 15.2 75.5 72.3 15.1 8.6 18.7 28.6 0.9 5.7 0.0 33.2 4.5 43.0 0.0 0.4 17.2 13.8 54.4 35.5 72.2 53.0 4.8 0.7 6.8 23.0 10.3 0.6 0.0 7.0 13.2 44.3 0.0 12.1 1.5 4.7 4.1 31.8 53.0 15.9 10.9 12.4 21.4 4.1 0.3 126.7 53.0 11.8 69.6 23.0 0.0 0.2 0.0 18.9 0.1 61.9 0.0 0.4 2.9 0.4 0.1 0.5 0.0 0.6 0.6 0.0 0.0 1.2 0.5 1.0 0.0 0.0 0.0 0.5 0.7 7.0 5.8 4.5 6.9 5.8 4.5 3.7 2.7 2.8 3.4 3.5 3.5 22.5 6.4 2.0 4.6 0.2 2.9 9.7 16.2 7.4 1.2 10.2 8.9 5.9 10.0 12.7 11.0 4.2 5.6 2.3 14.8 0.0 19.2 170.5 7.5 17.6 20.1 14.5 0.0 24.7 7.7 116.3 21.1 11.2 8.8 0.0 4.4 14.3 0.0 8.5 0.0 117.2 20.6 0.0 0.3 3.6 373.8 11.1 6.0 1.8 30.9 0.6 10.2 0.0 125.2 5.4 29.9 8.6 12.4 0.6 13.5 6.4 4.2 6.4 0.7 6.6 8.0 13.4 12.5 10.0 6.2 4.3 8.8 7.3 2.6 13.9 9.9 AHI1 "FLJ20069, JBTS3, ORF1" ENSG00000135541 "Abelson helper integration site 1" Q8N157 6 135283407-135498434 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation" "Developmental protein" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 1121.7;Excitatory neurons: 633.2;Inhibitory neurons: 655.2;Rod photoreceptor cells: 1631.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031698, HPA046684" Approved Approved Centrosome NA NA "Cluster 6: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Centrosome "HPA031698: AB_2673997, HPA046684: AB_2679752" "unprognostic (4.00e-2)" "unprognostic (2.86e-1)" "unprognostic (8.13e-2)" "unprognostic (1.02e-1)" "unprognostic (3.17e-2)" "unprognostic (2.18e-2)" "unprognostic (2.70e-3)" "unprognostic (2.11e-1)" "unprognostic (2.11e-1)" "unprognostic (4.58e-2)" "prognostic favorable (7.51e-5)" "unprognostic (2.81e-2)" "prognostic unfavorable (4.07e-9)" "unprognostic (2.49e-2)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" "unprognostic (6.19e-3)" 5.8 9.4 6.2 2.8 4.9 1.7 5.8 12.6 10.6 8.0 5.7 7.0 1.9 7.8 6.1 3.8 8.6 3.2 5.9 4.1 16.4 5.5 5.3 6.4 1.9 5.9 9.2 10.6 9.1 7.0 29.6 3.3 4.8 9.3 3.9 27.2 6.6 5.7 5.5 4.5 4.8 5.0 2.2 2.8 7.0 13.3 19.5 3.6 7.2 3.4 1.9 7.0 6.2 12.7 4.8 6.7 7.9 8.8 11.6 15.0 3.0 9.3 11.7 8.3 14.5 1.7 3.4 6.8 4.6 9.1 8.4 3.2 6.3 1.7 12.5 6.2 6.3 2.5 15.0 4.2 6.0 14.5 2.8 6.2 3.4 12.7 5.1 15.3 8.8 8.1 14.8 0.6 14.0 4.4 4.4 1.7 5.9 2.8 4.9 6.8 4.3 2.7 3.4 3.0 12.2 6.5 12.2 3.9 5.6 5.3 3.2 7.1 6.9 6.9 8.7 11.3 8.2 6.7 11.0 3.5 8.5 2.3 12.7 11.1 2.5 0.1 6.0 0.8 3.4 11.5 5.7 6.0 3.6 14.1 4.3 5.6 0.2 6.4 0.8 21.9 3.3 0.9 6.2 4.9 12.6 10.6 4.1 16.4 5.9 9.2 4.8 2.2 19.5 12.7 32.7 38.5 93.8 162.6 35.6 28.7 38.2 11.2 37.0 296.1 41.1 38.6 26.7 25.8 35.1 58.8 1121.7 25.8 64.0 43.9 13.7 29.5 327.4 92.7 65.1 43.8 101.8 10.7 633.2 44.4 18.2 66.8 61.7 50.7 58.3 49.8 21.0 17.5 13.3 329.7 655.2 52.4 24.4 6.5 19.3 375.4 67.7 20.7 32.0 89.9 9.0 93.4 11.3 171.9 272.1 22.5 43.1 65.1 36.6 30.5 7.1 13.6 65.2 1631.4 52.6 81.6 37.6 137.4 127.1 18.1 22.6 28.6 38.6 52.8 42.5 24.9 AK5 ENSG00000154027 "Adenylate kinase 5" Q9Y6K8 1 77282019-77559966 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 121.0" "Cell type enhanced" "Detected in many" "Early spermatids: 150.5;Excitatory neurons: 403.7;Inhibitory neurons: 167.3;Oligodendrocytes: 706.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 13.6;naive CD4 T-cell: 16.3" "Group enriched" "Detected in many" 12 "dendritic cells: 13.6;T-cells: 16.3" "Cell line enhanced" "Detected in many" "ASC TERT1: 93.7;BJ: 67.8;fHDF/TERT166: 77.5;LHCN-M2: 189.9;U-2 OS: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019128, HPA057255" Enhanced Supported "Centriolar satellite,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Centriolar satellite" "HPA019128: AB_1844682, HPA057255: AB_2683383" "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (1.13e-1)" "unprognostic (2.85e-2)" "unprognostic (1.03e-1)" "unprognostic (6.04e-2)" "unprognostic (2.20e-1)" "unprognostic (2.01e-2)" "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" "unprognostic (1.91e-2)" "prognostic favorable (3.88e-4)" "unprognostic (3.56e-3)" "unprognostic (6.17e-4)" "unprognostic (1.18e-1)" "unprognostic (5.96e-2)" "unprognostic (6.76e-2)" 1.0 1.6 75.9 1.5 101.2 3.9 18.9 19.4 115.0 1.3 0.8 2.6 1.0 0.7 0.6 1.0 1.0 1.0 1.0 121.0 31.5 1.4 0.1 0.4 2.3 27.2 30.2 0.5 1.6 0.7 3.4 1.2 25.6 2.3 1.0 3.0 3.0 2.1 0.3 2.0 1.0 0.8 31.0 2.1 2.4 9.4 31.7 0.8 1.1 0.8 1.5 0.7 0.7 81.1 0.2 3.6 2.9 0.1 34.8 93.7 1.2 67.8 14.4 10.8 4.6 0.5 1.7 0.6 0.5 77.5 4.4 0.4 0.2 0.0 5.5 2.6 0.7 0.5 1.2 0.4 1.8 0.6 0.2 11.6 0.5 2.1 4.3 37.9 31.5 0.3 0.9 0.7 189.9 0.7 0.0 0.6 3.9 18.4 24.5 1.7 7.1 1.6 29.3 1.1 15.3 3.5 0.2 0.2 4.4 0.3 0.3 0.5 7.9 26.1 58.4 1.6 2.2 15.2 14.7 0.3 5.2 3.5 9.8 1.2 0.8 0.1 3.8 0.2 0.5 0.9 3.6 1.9 13.6 0.9 16.3 9.1 0.6 0.2 0.2 1.5 1.7 2.3 75.9 101.2 19.4 115.0 121.0 31.5 27.2 30.2 25.6 31.0 31.7 81.1 0.7 0.0 0.0 10.7 0.4 0.3 0.4 0.0 1.2 1.3 54.0 27.3 1.1 0.0 0.0 1.8 0.0 1.9 5.6 0.3 7.9 0.3 150.5 1.1 0.1 1.3 12.0 0.8 403.7 0.6 56.3 1.5 1.1 1.7 0.0 0.0 0.4 0.0 2.4 13.5 167.3 0.3 0.0 0.0 0.6 29.2 1.2 0.4 3.6 41.2 1.9 0.0 47.4 60.8 706.6 0.1 1.1 0.7 0.1 2.9 0.0 7.8 0.0 0.3 0.0 1.2 6.3 10.2 91.0 0.0 0.3 2.9 4.2 0.1 0.2 0.1 AKAP6 "ADAP6, AKAP100, KIAA0311, mAKAP, PRKA6" ENSG00000151320 "A-kinase anchoring protein 6" Q13023 14 32329298-32837684 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.8;heart muscle: 54.6;skeletal muscle: 47.5;tongue: 50.7" "Group enriched" "Detected in many" 6 "Excitatory neurons: 601.6;Inhibitory neurons: 663.1;Oligodendrocyte precursor cells: 412.7;Oligodendrocytes: 1162.5" "Cancer enhanced" "Detected in many" "glioma: 2.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive B-cell: 3.5" "Lineage enriched" "Detected in single" 6 "B-cells: 3.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001983, HPA048741" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB001983: , HPA048741: AB_2680506" "unprognostic (1.99e-1)" "unprognostic (9.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.37e-1)" "unprognostic (2.52e-1)" "unprognostic (4.33e-2)" "unprognostic (1.41e-4)" "unprognostic (1.81e-3)" "unprognostic (1.93e-2)" "unprognostic (4.49e-3)" "unprognostic (1.24e-3)" "unprognostic (3.54e-1)" "unprognostic (3.33e-16)" "unprognostic (8.57e-2)" "unprognostic (1.27e-1)" "unprognostic (5.14e-3)" "unprognostic (1.79e-3)" 1.6 5.6 21.0 2.5 31.4 0.5 4.6 20.3 24.6 1.6 0.0 5.5 1.8 3.9 5.6 5.4 2.9 3.7 54.6 16.9 36.7 2.9 2.1 2.3 0.8 52.0 34.9 2.5 0.8 3.5 3.6 4.5 51.9 2.0 2.2 13.6 2.6 1.2 47.5 1.2 2.4 7.7 22.4 0.8 2.0 5.9 34.8 0.9 4.8 50.7 0.7 4.2 1.5 59.8 0.3 0.8 1.0 0.9 0.2 1.7 0.2 1.3 3.6 0.2 0.4 1.1 1.0 1.4 0.9 15.8 0.6 0.8 1.2 1.4 0.5 1.3 1.0 1.3 1.5 1.1 0.5 0.1 0.3 1.8 1.3 0.0 0.4 0.6 0.1 2.1 0.3 4.1 1.1 0.8 0.7 0.2 0.2 1.1 1.1 0.7 4.9 0.6 0.4 1.2 5.2 4.2 1.1 0.7 3.2 0.7 2.9 0.1 0.3 0.2 0.8 0.8 0.5 2.5 2.4 0.6 1.5 0.1 5.4 0.3 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.2 3.5 0.4 0.6 0.5 0.1 0.1 0.4 0.0 0.3 21.0 31.4 20.3 24.6 16.9 36.7 52.0 34.9 51.9 22.4 34.8 59.8 0.6 6.4 2.7 111.3 2.2 2.3 2.9 1.0 5.2 49.2 8.7 3.0 108.0 0.0 4.9 1.8 50.1 0.8 0.1 1.1 0.0 0.8 32.4 6.7 0.4 1.7 1.2 0.0 601.6 0.5 0.3 6.3 0.0 1.4 1.3 0.6 1.1 2.7 1.2 26.9 663.1 0.6 4.1 0.6 1.6 13.7 14.6 1.1 7.2 23.4 0.7 2.5 0.0 412.7 1162.5 0.3 0.1 33.1 2.0 1.1 1.9 1.5 23.6 21.5 19.7 25.8 14.3 25.9 1.3 1.1 1.6 0.4 0.6 3.4 0.9 0.9 AL035078.4 ENSG00000285283 "Novel protein" 11 31812391-32104665 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8.8;lymphoid tissue: 5.7;retina: 7.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 224.4;RH-30: 110.7;RT4: 139.0;TIME: 116.0" HPA038474 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Endoplasmic reticulum" "HPA038474: AB_10672595" 1.3 0.0 0.4 5.7 0.7 0.5 0.0 2.5 1.4 0.3 0.0 8.8 0.0 2.3 0.1 2.2 0.7 0.0 0.0 0.4 1.3 0.3 1.6 1.0 0.0 1.5 1.2 1.1 0.0 0.0 0.4 1.1 0.2 0.2 7.4 0.0 0.0 4.1 0.0 1.5 0.2 1.0 0.2 2.1 0.5 0.8 0.3 0.0 0.0 0.5 0.1 1.6 14.7 33.3 4.9 22.6 2.8 0.0 0.6 224.4 40.6 18.6 9.5 11.2 25.0 0.0 46.0 12.7 14.3 7.1 21.8 12.1 14.7 13.1 0.8 13.4 24.1 0.0 0.0 11.3 1.8 0.0 0.0 23.7 6.4 3.8 4.4 0.1 3.7 13.5 0.0 0.2 13.8 0.0 2.6 0.0 0.3 8.7 110.7 2.7 0.0 139.0 12.9 3.7 36.6 1.4 16.3 0.0 13.9 0.5 116.0 62.2 27.3 30.4 64.6 0.0 0.1 0.6 74.6 2.9 24.7 0.0 0.8 0.0 0.3 0.4 0.4 0.2 0.0 0.2 1.0 0.0 0.0 0.1 0.1 0.8 0.3 0.1 0.0 0.4 0.4 0.7 2.5 1.4 0.4 1.3 1.5 1.2 1.1 1.0 0.8 1.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL132671.2 ENSG00000282218 "Novel protein, GOPC-ROS1 readthrough" 6 117318211-117573571 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 15 "Alveolar cells type 2: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 36 "U-138 MG: 8.9" "Low region specificity" "Detected in all" HPA019477 Uncertain Approved "Golgi apparatus" NA NA "Cluster 10: BJ & FHDF - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus" "HPA019477: AB_1849890" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL139300.1 ENSG00000256500 "Novel protein" 14 103562962-103685924 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.7;tongue: 16.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;granulocytes: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA044617, HPA052450" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA044617: AB_2679024, HPA052450: AB_2681838" "unprognostic (1.56e-1)" 4.3 2.6 0.9 2.9 1.0 0.8 1.3 0.9 5.2 1.2 0.2 1.4 0.0 0.8 0.2 1.6 0.9 0.1 12.8 1.4 1.6 0.5 0.5 1.0 1.6 1.0 1.7 1.0 2.5 7.5 3.8 0.1 1.6 1.4 0.0 3.5 1.6 1.1 31.7 0.6 0.7 3.1 0.7 0.4 0.7 9.4 1.1 2.9 0.1 16.5 1.7 3.4 0.5 1.2 8.1 15.9 18.5 0.6 8.2 7.8 5.6 25.7 19.7 29.3 17.0 9.5 12.1 22.0 17.2 19.2 19.3 5.5 12.4 13.3 17.4 6.7 0.0 8.7 6.1 8.7 9.7 10.8 3.4 8.6 0.6 13.5 11.0 14.5 15.2 13.7 11.6 3.4 21.4 15.4 18.9 1.2 12.1 19.5 13.9 7.7 12.1 11.4 13.6 9.0 22.1 12.2 14.6 5.7 12.1 6.2 13.0 6.6 8.4 11.3 9.2 16.9 10.4 6.4 8.6 25.6 19.6 3.4 9.8 0.2 0.8 1.1 0.5 1.3 0.7 0.3 0.7 0.9 0.4 1.3 1.0 0.4 0.7 0.6 1.6 1.5 1.4 0.3 0.9 1.0 0.9 5.2 1.4 1.6 1.0 1.7 1.6 0.7 1.1 1.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 438.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 737.2;Oligodendrocyte precursor cells: 680.1;Oligodendrocytes: 981.1;Respiratory ciliated cells: 318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Cell line enhanced" "Detected in many" "hTERT-HME1: 393.4;U-138 MG: 473.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" NA NA 1600000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB002148: AB_442053, HPA010926: AB_1078449" "unprognostic (6.82e-2)" "unprognostic (2.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-2)" "unprognostic (1.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.15e-4)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (9.57e-2)" "unprognostic (7.76e-2)" 7.7 32.7 31.3 12.2 48.1 10.5 81.0 42.4 47.2 28.0 14.4 16.6 17.0 15.5 35.4 8.2 49.1 23.3 9.6 32.4 70.6 22.2 47.9 74.1 9.9 50.7 54.9 57.6 32.7 438.9 19.2 12.1 51.7 32.7 14.5 3.6 33.8 39.6 0.8 11.0 17.4 16.2 44.9 6.3 33.4 4.5 45.7 14.2 62.4 5.0 14.5 25.6 6.4 85.0 248.4 93.7 65.9 33.7 97.6 42.7 0.6 197.7 115.1 124.9 173.8 0.8 50.5 17.3 80.3 280.6 68.8 186.5 10.6 157.4 366.1 16.6 16.6 2.4 65.8 4.6 109.6 101.3 0.8 76.0 114.9 159.9 393.4 346.8 139.3 17.9 0.3 28.6 165.9 16.9 14.5 37.0 13.7 79.3 104.8 9.4 5.9 1.0 188.9 27.2 47.5 131.9 20.6 19.6 12.9 25.9 37.7 66.3 291.6 473.7 162.3 20.9 237.2 0.3 0.6 1.8 108.0 21.1 207.4 0.0 4.7 3.5 0.6 2.1 1.9 4.7 1.5 0.9 29.6 3.0 0.3 0.2 5.3 0.6 1.2 10.5 2.4 3.2 31.3 48.1 42.4 47.2 32.4 70.6 50.7 54.9 51.7 44.9 45.7 85.0 4.5 737.2 143.6 238.6 17.9 12.1 22.8 65.8 12.0 3.0 112.4 47.9 10.1 62.9 255.3 16.5 2.1 0.7 19.5 9.1 1.9 18.5 66.5 108.6 20.1 11.9 16.8 6.3 143.0 43.0 0.7 37.0 23.4 158.1 11.4 29.5 3.6 44.1 57.5 1.7 287.0 16.3 46.8 51.0 162.6 60.1 3.7 86.4 24.9 40.3 93.4 1.3 1.0 680.1 981.1 55.2 8.5 6.4 21.8 117.5 9.6 24.2 318.3 0.8 0.0 7.9 21.8 8.1 5.5 30.1 20.2 0.8 8.9 22.8 10.4 105.4 ALPK2 HAK ENSG00000198796 "Alpha kinase 2" Q86TB3 18 58481247-58629091 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "heart muscle: 41.9;skeletal muscle: 38.3;tongue: 33.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 120.4;Cone photoreceptor cells: 47.9;Early spermatids: 15.9;Late spermatids: 24.3;monocytes: 18.1" "Cancer enriched" "Detected in some" 6 "renal cancer: 7.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 51.2;BJ hTERT+: 31.0;fHDF/TERT166: 46.6;U-138 MG: 25.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027377, HPA027976, HPA028084, HPA029801" Uncertain Approved Cytosol NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA027377: AB_10600635, HPA027976: AB_10611246, HPA028084: AB_10601996, HPA029801: AB_10602006" "unprognostic (7.35e-2)" "unprognostic (4.91e-2)" "unprognostic (1.64e-1)" "unprognostic (4.60e-3)" "unprognostic (2.64e-1)" "unprognostic (8.27e-2)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (1.06e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.20e-5)" "unprognostic (5.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.73e-2)" "unprognostic (3.20e-2)" 0.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.8 0.3 0.0 0.9 41.9 0.4 0.0 9.2 4.5 0.1 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.2 2.1 0.3 0.0 38.3 0.5 1.0 0.1 0.0 0.5 1.7 1.1 0.0 3.5 0.0 33.2 4.4 1.5 0.0 0.0 0.0 13.7 0.9 0.0 0.4 3.4 0.3 51.2 31.0 21.2 18.1 3.4 0.0 0.0 5.2 46.6 2.9 0.0 0.0 0.0 21.5 11.5 0.0 0.0 4.4 1.8 2.7 0.0 0.0 3.0 0.0 6.4 0.2 0.7 0.0 0.0 0.0 0.4 13.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 11.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 8.3 0.0 0.0 0.0 25.3 11.2 3.5 8.7 20.9 19.2 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.2 0.1 4.8 120.4 0.0 0.0 0.0 47.9 0.0 0.1 0.0 1.9 1.5 15.9 0.0 2.3 0.9 0.0 0.0 1.0 0.7 0.0 8.9 0.0 0.1 0.0 4.0 0.4 3.0 0.7 1.7 0.7 0.0 0.0 0.3 3.0 24.3 0.3 2.4 0.0 0.0 18.1 2.6 0.0 0.0 0.8 0.2 2.3 0.0 0.6 0.0 0.3 13.6 0.0 0.9 0.0 3.8 1.7 1.1 0.1 0.0 0.9 0.1 0.3 0.0 0.0 0.0 AMPD2 SPG63 ENSG00000116337 "Adenosine monophosphate deaminase 2" Q01433 1 109616104-109632051 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Horizontal cells: 52.2;Macrophages: 52.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 19.4;eosinophil: 19.2;intermediate monocyte: 40.7;myeloid DC: 18.9;neutrophil: 61.1;non-classical monocyte: 44.6" "Group enriched" "Detected in all" 5 "dendritic cells: 18.9;granulocytes: 61.1;monocytes: 44.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027137, HPA045760" Approved Enhanced Cytosol NA NA 230000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Cytosol "HPA027137: AB_2672129, HPA045760: AB_2679443" "unprognostic (2.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.50e-1)" "unprognostic (1.43e-3)" "unprognostic (9.01e-2)" "unprognostic (5.25e-2)" "unprognostic (3.91e-3)" "unprognostic (1.71e-1)" "unprognostic (4.02e-1)" "unprognostic (1.23e-1)" "unprognostic (8.10e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.78e-10)" "unprognostic (9.16e-2)" "unprognostic (2.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" 9.3 17.5 31.2 12.0 41.6 28.6 7.4 22.9 34.7 13.1 36.6 7.5 10.7 11.5 4.1 7.2 13.1 8.8 7.2 34.8 37.0 10.5 16.2 13.4 7.6 34.7 31.7 17.5 10.0 9.4 45.8 7.6 33.6 10.8 4.1 10.5 9.2 12.0 3.3 8.5 10.8 7.1 27.9 19.0 8.6 4.3 39.3 4.9 10.6 1.5 5.9 7.5 11.4 29.0 20.6 22.5 20.5 20.1 18.0 18.7 8.6 25.6 57.2 24.9 25.0 19.1 7.0 10.5 21.8 39.1 16.0 11.3 15.8 20.0 13.4 13.0 20.7 46.0 15.6 19.3 24.9 15.7 45.7 23.3 13.2 32.5 24.1 28.2 26.7 17.0 17.4 13.0 16.0 23.2 26.7 29.0 20.6 17.1 22.9 18.6 15.8 17.3 24.2 8.7 19.3 22.4 17.4 19.8 24.6 5.7 10.4 16.2 16.7 27.7 39.0 33.7 25.4 48.4 28.4 12.1 50.8 25.9 35.1 0.5 19.4 19.2 5.3 40.7 8.0 5.3 5.2 4.9 18.9 2.7 6.4 5.1 61.1 4.3 44.6 2.6 4.0 12.3 31.2 41.6 22.9 34.7 34.8 37.0 34.7 31.7 33.6 27.9 39.3 29.0 3.6 3.2 5.5 13.7 9.4 8.9 5.4 5.0 9.1 41.0 8.8 11.4 3.2 12.8 5.4 0.0 62.6 4.9 10.0 4.2 7.9 9.8 3.5 4.4 9.4 7.1 17.5 5.0 13.3 11.2 8.6 12.6 14.3 5.5 3.8 11.0 6.1 20.5 10.8 52.2 17.6 9.6 2.0 42.1 42.0 1.3 13.1 52.5 5.4 6.5 16.1 10.5 6.2 12.1 10.6 10.3 3.0 21.4 11.1 11.1 6.1 4.5 4.2 7.2 13.1 8.8 10.6 4.2 3.8 7.9 8.1 2.6 15.4 8.5 10.7 4.0 ANKLE2 "KIAA0692, Lem4, LEMD7" ENSG00000176915 "Ankyrin repeat and LEM domain containing 2" Q86XL3 12 132725503-132761832 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 215.7;Urothelial cells: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003602, HPA074838" Uncertain Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum, Plasma membrane" "HPA003602: AB_1858349, HPA074838: " "unprognostic (4.43e-2)" "unprognostic (6.92e-2)" "unprognostic (7.97e-2)" "unprognostic (9.84e-3)" "unprognostic (1.97e-2)" "unprognostic (5.81e-2)" "prognostic unfavorable (3.97e-6)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (4.76e-2)" "unprognostic (6.10e-2)" "prognostic unfavorable (1.90e-8)" "unprognostic (1.42e-1)" "unprognostic (1.42e-1)" "unprognostic (6.92e-3)" "unprognostic (2.09e-1)" 30.0 37.6 12.4 27.0 13.3 38.4 27.8 15.2 16.6 25.4 21.9 23.8 17.8 24.9 19.0 33.6 25.2 17.4 22.0 13.8 14.1 21.8 22.9 31.3 31.6 12.3 12.4 27.1 24.6 17.9 23.1 20.4 12.3 23.9 16.1 12.3 26.1 15.6 29.3 36.9 33.3 21.9 12.0 37.9 24.1 55.7 14.3 26.2 23.3 18.3 31.2 25.0 27.6 13.2 50.7 46.4 47.3 29.5 26.9 42.1 59.1 60.2 44.7 59.0 45.0 53.2 33.6 39.5 30.7 53.1 39.5 59.2 41.8 54.8 56.2 17.0 51.6 50.1 84.0 25.2 29.9 54.6 34.0 39.1 54.9 56.2 41.3 108.8 42.8 32.0 46.1 15.1 61.2 36.4 51.1 89.4 40.1 24.8 43.9 58.0 31.1 16.7 42.6 64.9 57.9 35.6 77.7 32.4 27.1 44.1 56.9 39.1 61.5 70.5 50.9 38.0 68.1 27.9 29.5 47.9 54.7 35.8 40.5 0.9 1.2 4.4 1.8 1.1 2.4 2.7 2.6 2.8 1.7 2.8 2.4 2.0 0.7 2.7 1.3 1.7 2.6 0.7 12.4 13.3 15.2 16.6 13.8 14.1 12.3 12.4 12.3 12.0 14.3 13.2 38.0 73.7 31.2 18.3 43.2 67.3 92.0 38.2 32.5 32.3 31.2 27.1 24.6 27.1 51.3 31.3 45.9 29.2 41.1 33.8 1.9 33.2 109.1 58.6 52.4 36.3 20.8 23.1 21.0 32.7 35.5 35.7 35.2 119.2 18.4 38.3 22.9 12.9 20.1 32.0 17.8 18.0 24.4 19.7 47.6 24.5 25.1 35.5 33.8 16.9 40.6 21.9 47.4 18.1 18.4 101.9 24.8 28.2 47.6 116.9 18.8 8.5 32.3 39.7 26.3 39.2 40.5 215.7 61.8 44.8 72.9 36.5 44.7 31.6 24.0 168.7 ANKRD13A "ANKRD13, NY-REN-25" ENSG00000076513 "Ankyrin repeat domain 13A" Q8IZ07 12 109999186-110039763 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 160.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 205.4;HBF TERT88: 200.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039488, HPA043218" Enhanced Supported "Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA039488: AB_10673612, HPA043218: AB_2678367" "unprognostic (1.54e-1)" "unprognostic (3.94e-3)" "unprognostic (5.81e-1)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "prognostic favorable (7.70e-6)" "unprognostic (5.68e-2)" "unprognostic (1.31e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (9.71e-3)" "unprognostic (1.67e-1)" "unprognostic (2.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.13e-2)" "unprognostic (1.08e-1)" "unprognostic (5.29e-2)" 13.2 10.9 6.3 36.5 10.0 36.0 16.4 8.8 8.1 14.1 6.1 21.8 14.3 11.9 6.6 31.7 12.3 22.9 10.7 7.1 7.4 17.6 15.3 26.9 54.0 8.4 8.7 16.3 12.3 17.4 4.6 24.4 9.0 17.9 22.4 8.7 27.5 24.6 6.9 22.6 17.6 24.4 7.5 32.8 17.1 60.9 8.4 27.9 28.2 8.7 66.7 25.9 13.2 15.0 163.7 7.3 16.9 15.6 25.4 25.1 20.8 160.9 150.5 149.8 79.3 21.2 10.3 107.8 12.4 205.4 18.7 19.0 21.7 24.0 200.3 122.3 19.2 39.9 15.6 17.4 22.2 46.8 46.2 21.9 24.9 63.8 36.5 37.3 23.0 24.9 31.6 17.2 66.5 5.8 41.3 19.5 9.3 11.7 34.1 35.8 47.3 42.7 21.2 20.7 34.7 16.5 29.6 57.0 19.5 11.4 26.0 38.5 29.2 111.6 20.0 62.2 87.4 36.8 23.3 144.1 54.3 31.7 16.5 1.5 1.2 5.6 0.5 2.5 1.5 2.0 1.3 0.6 1.5 1.2 0.7 1.0 3.5 0.9 1.1 1.0 0.6 0.7 6.3 10.0 8.8 8.1 7.1 7.4 8.4 8.7 9.0 7.5 8.4 15.0 15.7 48.1 32.5 13.4 75.5 29.3 18.7 11.0 15.4 24.4 23.1 16.9 13.0 28.6 30.5 57.0 14.6 16.9 31.2 30.3 21.5 29.2 104.7 22.0 12.3 14.9 18.7 19.4 15.9 17.6 21.0 15.5 16.3 29.5 13.3 18.5 15.7 17.3 15.4 25.2 26.9 9.4 4.1 37.1 26.9 160.4 11.8 33.7 14.2 16.9 34.2 9.7 21.6 17.6 46.0 20.8 12.5 21.8 33.0 16.2 16.0 9.8 37.6 14.2 32.9 50.3 18.0 71.1 15.0 23.9 37.8 37.6 31.8 16.9 17.0 25.7 ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin actin binding protein" Q9NQW6 7 36389821-36453791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 266.0" "Group enriched" "Detected in many" 5 "Early spermatids: 156.4;Oligodendrocytes: 441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBF TERT88: 655.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Midbody "CAB033902: AB_2058302, CAB062547: AB_2665622, CAB068175: AB_2665623, HPA005680: AB_2667388, HPA050556: AB_2681175" "unprognostic (4.23e-2)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.67e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (5.97e-7)" "prognostic unfavorable (6.99e-5)" "unprognostic (2.69e-2)" "unprognostic (3.66e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (3.13e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.29e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (4.04e-3)" 1.2 0.7 59.8 5.2 134.5 36.4 2.0 125.1 72.7 1.8 18.4 6.0 4.4 1.8 0.2 10.4 0.9 2.1 0.8 59.3 83.6 0.4 1.2 1.4 6.7 162.3 106.5 0.9 0.6 0.2 0.2 8.9 160.2 0.9 8.0 0.3 1.7 0.4 0.3 13.6 4.3 14.9 99.2 1.2 4.8 12.4 102.3 16.0 0.8 0.3 9.5 3.2 3.2 266.0 476.1 96.5 79.3 61.0 10.7 26.9 85.6 292.5 169.3 344.4 256.0 66.4 142.7 23.9 82.1 148.6 182.8 237.0 63.4 170.7 655.4 16.1 46.0 32.7 104.8 55.8 1.7 47.3 36.7 6.0 7.7 225.3 147.2 40.8 109.3 31.2 69.6 48.8 284.4 71.0 40.0 54.8 88.5 71.9 102.3 29.1 238.2 15.9 76.5 76.5 33.5 39.5 154.1 175.8 26.1 109.6 119.0 53.6 104.5 214.2 239.0 127.6 346.6 20.1 34.2 43.2 72.9 74.9 460.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 59.8 134.5 125.1 72.7 59.3 83.6 162.3 106.5 160.2 99.2 102.3 266.0 0.4 0.0 1.1 2.3 1.0 14.1 1.9 8.3 7.4 0.0 1.9 2.0 0.6 0.0 3.2 0.0 0.0 13.8 1.1 2.8 0.0 0.7 156.4 18.9 3.2 1.9 0.0 35.3 3.4 0.2 23.2 6.9 10.2 12.8 0.0 15.4 1.1 0.5 9.8 0.0 5.7 3.4 6.1 1.6 5.9 53.3 1.2 2.7 0.0 0.0 0.0 0.0 0.0 1.5 441.3 0.6 0.1 0.0 8.8 1.6 0.8 0.3 10.4 0.0 0.0 0.4 5.2 20.0 17.7 27.1 9.2 2.9 2.6 1.7 6.0 3.3 ANO10 "FLJ10375, MGC47890, SCAR10, TMEM16K" ENSG00000160746 "Anoctamin 10" Q9NW15 3 43354859-43691594 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 123.3;Excitatory neurons: 77.4;Inhibitory neurons: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016624, HPA051569" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA016624: , HPA051569: AB_2681537" "unprognostic (1.51e-3)" "unprognostic (1.38e-2)" "prognostic favorable (6.70e-4)" "prognostic favorable (1.11e-4)" "unprognostic (4.23e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (7.99e-3)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.41e-6)" "unprognostic (9.83e-3)" "unprognostic (1.22e-1)" "unprognostic (5.19e-3)" "unprognostic (5.71e-2)" 26.6 14.1 17.6 15.1 18.6 33.0 21.8 23.9 20.9 22.3 18.4 39.4 61.1 21.6 13.6 25.3 13.9 19.4 12.7 18.1 21.1 29.9 14.1 16.9 7.6 22.7 22.9 13.9 15.2 23.7 13.9 18.1 23.2 14.2 33.7 10.1 28.6 20.2 15.5 32.0 54.7 28.0 19.6 9.1 13.5 13.0 19.8 7.1 24.5 11.6 9.7 18.1 21.5 24.1 30.6 23.6 26.1 27.4 101.1 53.5 31.2 87.7 141.1 42.0 54.4 16.2 27.5 3.1 27.4 114.8 43.1 16.3 20.6 47.0 52.6 33.6 14.2 39.4 28.7 17.7 43.9 7.2 31.1 50.5 36.3 53.6 71.8 79.4 100.3 18.7 30.8 24.9 95.2 20.8 7.8 5.2 31.3 23.7 28.6 6.3 18.7 10.2 85.5 31.4 6.4 19.4 34.4 27.0 19.8 45.3 59.5 14.5 84.7 66.2 24.4 70.2 40.7 15.7 22.9 1.1 60.2 14.6 44.2 7.4 19.0 1.4 6.7 11.1 3.8 2.7 4.6 4.5 13.1 2.5 3.9 6.0 32.8 9.7 12.7 2.3 5.4 7.0 17.6 18.6 23.9 20.9 18.1 21.1 22.7 22.9 23.2 19.6 19.8 24.1 24.3 6.4 3.2 70.2 4.1 5.6 5.8 6.9 8.0 8.0 18.2 8.4 5.2 8.6 13.2 14.7 0.0 14.4 3.7 38.5 123.3 21.6 2.9 11.8 23.6 17.8 9.6 11.8 77.4 17.8 19.5 10.6 10.2 31.2 2.5 6.8 23.6 10.7 11.6 10.1 97.9 23.8 10.2 9.6 5.3 5.2 5.6 9.1 14.2 69.3 9.2 17.1 5.2 71.4 46.4 11.7 22.1 10.1 2.6 4.4 58.4 19.0 4.0 3.6 6.6 19.1 15.7 17.1 23.6 8.7 6.1 17.1 5.8 6.2 26.9 4.8 AP3B1 "ADTB3A, HPS2" ENSG00000132842 "Adaptor related protein complex 3 subunit beta 1" O00203 5 78002326-78294698 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 231.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038737, HPA045458" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA 38000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Golgi apparatus" "HPA038737: AB_10670788, HPA045458: AB_2679333" "unprognostic (9.14e-2)" "unprognostic (2.02e-1)" "prognostic favorable (1.37e-5)" "unprognostic (8.17e-2)" "unprognostic (2.95e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-3)" "unprognostic (7.47e-3)" "unprognostic (4.51e-1)" "unprognostic (9.05e-3)" "unprognostic (1.01e-1)" "unprognostic (6.97e-2)" "prognostic favorable (7.97e-6)" "unprognostic (1.65e-1)" "unprognostic (1.35e-1)" "unprognostic (1.98e-1)" "unprognostic (3.39e-2)" 21.5 21.5 21.1 19.6 26.1 21.9 21.3 22.3 26.4 20.7 23.0 24.1 19.8 17.8 53.9 30.8 15.8 15.9 19.0 19.6 23.4 30.3 15.9 17.2 22.5 23.4 24.4 13.0 24.9 29.3 40.4 19.6 24.5 16.9 28.3 8.8 26.4 16.4 15.8 22.5 20.8 20.5 23.3 21.6 23.0 13.2 23.6 23.2 27.2 13.0 24.8 20.1 21.9 26.5 51.3 40.3 45.4 63.1 53.2 64.5 39.5 56.3 66.1 50.1 67.5 31.4 44.1 53.7 32.5 69.4 41.7 36.6 45.0 94.1 62.7 61.7 31.7 37.4 33.9 55.5 31.1 33.7 47.1 46.2 34.0 42.3 42.5 47.7 64.1 10.9 27.3 34.3 86.9 31.6 43.4 52.2 24.1 37.4 23.9 45.2 80.2 74.4 72.7 47.5 16.0 25.7 52.3 33.7 49.7 37.1 40.9 55.6 65.0 37.4 29.1 45.4 57.4 26.3 43.3 36.3 48.5 48.5 48.4 18.3 12.6 11.3 9.6 12.5 10.6 31.3 8.0 10.0 17.2 40.1 6.6 8.8 15.4 9.6 17.3 14.2 10.4 8.1 21.1 26.1 22.3 26.4 19.6 23.4 23.4 24.4 24.5 23.3 23.6 26.5 31.6 44.8 33.7 82.3 59.0 15.8 22.1 28.1 22.8 16.2 18.8 14.1 29.0 10.0 37.5 31.3 22.9 30.9 37.1 36.9 25.4 35.8 12.0 27.7 38.8 33.3 19.2 27.3 59.7 38.0 38.7 32.0 35.2 40.8 32.9 26.1 23.2 17.0 39.5 20.2 57.3 34.1 26.4 41.9 24.8 20.2 15.8 47.3 26.6 118.0 66.5 21.5 32.0 86.5 231.0 43.5 25.0 16.6 44.0 20.7 30.0 27.2 29.8 27.5 26.3 36.2 28.5 16.1 10.1 28.9 23.4 29.8 39.9 31.2 28.0 22.2 APBA1 "D9S411E, MINT1, X11" ENSG00000107282 "Amyloid beta precursor protein binding family A member 1" Q02410 9 69427532-69672371 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5" "Group enriched" "Detected in many" 7 "Astrocytes: 53.5;Excitatory neurons: 130.3;Horizontal cells: 69.0;Inhibitory neurons: 181.6;Microglial cells: 78.7;Oligodendrocyte precursor cells: 141.3;Oligodendrocytes: 106.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 7.2;BJ hTERT+: 6.0;HAP1: 17.2;SCLC-21H: 6.5;TIME: 7.8;U-138 MG: 6.9;U-266/70: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061287 Supported "Golgi apparatus" NA NA "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA061287: AB_2684467" "unprognostic (4.02e-2)" "unprognostic (4.64e-2)" "unprognostic (7.29e-2)" "unprognostic (8.94e-3)" "unprognostic (1.06e-1)" "unprognostic (1.53e-1)" "unprognostic (4.21e-3)" "unprognostic (8.49e-3)" "unprognostic (2.22e-1)" "unprognostic (2.33e-1)" "unprognostic (2.46e-5)" "unprognostic (1.60e-1)" "unprognostic (3.09e-2)" "unprognostic (4.99e-3)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (4.66e-3)" 2.9 1.2 14.1 0.7 13.1 0.0 2.5 0.0 16.5 3.6 0.0 2.9 0.6 4.1 0.1 1.8 2.5 1.3 3.0 16.0 9.5 2.2 11.9 1.4 0.6 15.1 13.8 5.3 1.9 6.8 6.3 1.4 16.1 1.9 1.9 3.2 2.9 1.1 2.0 3.9 1.8 0.8 0.0 3.8 2.0 2.8 7.9 0.2 2.0 0.6 0.3 2.8 3.6 0.9 0.0 0.0 0.6 0.0 3.1 2.2 0.1 7.2 6.0 0.1 0.1 0.0 0.0 0.0 3.2 3.0 0.0 0.1 17.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.9 0.3 0.0 0.0 2.9 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.0 2.5 6.5 4.2 0.4 0.9 0.1 0.2 0.0 0.0 7.8 6.9 0.8 0.0 0.5 7.1 3.3 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 13.1 0.0 16.5 16.0 9.5 15.1 13.8 16.1 0.0 7.9 0.9 1.0 0.0 0.0 53.5 0.0 1.8 1.2 0.2 0.0 15.4 2.0 2.2 4.9 0.0 0.2 0.0 4.2 0.8 0.0 3.7 0.0 0.1 0.3 0.9 1.7 1.4 4.2 0.0 130.3 0.0 0.6 1.7 0.0 1.0 0.0 1.3 3.3 5.8 3.1 69.0 181.6 1.6 0.0 3.7 1.4 0.6 2.5 1.4 0.0 78.7 1.0 3.2 0.0 141.3 106.2 0.2 0.4 10.9 0.0 0.6 0.0 0.4 0.1 9.1 0.0 1.6 2.3 1.1 1.3 0.5 2.4 0.4 0.5 6.0 1.2 0.4 APBB1 "Fe65, RIR" ENSG00000166313 "Amyloid beta precursor protein binding family B member 1" O00213 11 6395124-6419414 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 85.6" "Lineage enriched" "Detected in all" 5 "T-cells: 85.6" "Cell line enhanced" "Detected in many" "SCLC-21H: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038521, HPA038522" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA038521: AB_2676058, HPA038522: AB_2676059" "unprognostic (4.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.84e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (7.30e-2)" "unprognostic (3.22e-3)" "unprognostic (2.36e-1)" "prognostic favorable (1.86e-5)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-13)" "unprognostic (1.32e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (1.09e-2)" 18.1 23.8 101.7 11.9 119.4 2.7 18.0 116.6 121.1 39.5 65.1 43.3 7.0 43.5 4.3 14.9 38.3 11.4 42.0 123.3 105.3 21.5 3.8 22.5 13.9 123.9 106.0 39.2 16.3 21.4 61.3 8.6 135.0 23.7 4.7 23.3 13.4 25.9 42.3 12.2 19.2 33.2 109.4 13.8 19.4 12.7 112.1 28.9 19.1 54.0 11.1 31.2 23.5 152.9 0.0 14.9 50.6 22.8 26.7 27.4 0.2 24.6 41.7 41.2 51.4 26.4 10.3 0.0 3.6 44.3 36.9 0.5 44.4 7.5 19.4 27.8 33.7 0.3 9.3 0.9 19.3 0.2 9.9 24.8 1.9 19.4 2.9 35.3 51.7 1.2 1.1 0.7 15.3 0.5 0.5 0.1 18.3 0.8 15.5 0.2 2.0 0.2 1.7 0.2 68.1 37.6 3.6 3.0 15.9 15.2 2.1 3.4 22.8 4.2 24.8 27.5 5.0 13.8 6.8 2.0 21.1 0.0 14.3 8.4 1.7 0.3 23.2 1.5 25.2 6.7 32.5 30.2 1.7 16.2 85.6 51.7 1.6 16.5 0.6 0.3 48.7 29.9 101.7 119.4 116.6 121.1 123.3 105.3 123.9 106.0 135.0 109.4 112.1 152.9 9.6 19.2 5.4 22.9 7.5 5.0 12.1 3.6 12.0 45.8 6.6 5.7 50.5 11.5 5.4 5.5 22.9 0.4 4.6 1.1 25.4 18.2 5.6 7.6 9.5 13.9 19.3 4.0 47.1 4.2 0.7 15.2 4.6 2.3 1.3 10.8 15.7 3.3 1.2 40.4 44.8 1.2 0.0 1.9 4.0 13.1 9.6 1.8 8.8 7.5 3.2 24.7 9.2 49.3 102.3 8.0 1.7 19.2 1.4 8.3 0.4 21.6 17.3 20.1 6.6 10.0 17.3 6.9 13.7 3.2 2.8 0.8 20.1 7.0 1.3 5.4 APCDD1 B7323 ENSG00000154856 "APC down-regulated 1" Q8J025 18 10454635-10489949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 129.8" "Cell type enhanced" "Detected in many" "Astrocytes: 120.5;Cholangiocytes: 85.8;Endometrial stromal cells: 429.5;Melanocytes: 80.0;Oligodendrocyte precursor cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 32.0;BJ hTERT+: 70.4;HaCaT: 43.0;HHSteC: 18.9;HSkMC: 39.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (1.21e-1)" "unprognostic (2.85e-2)" "unprognostic (1.11e-1)" "prognostic favorable (6.39e-4)" "prognostic favorable (8.23e-4)" "unprognostic (5.61e-3)" "unprognostic (6.79e-3)" "unprognostic (1.24e-1)" "unprognostic (5.59e-3)" "unprognostic (2.59e-2)" "unprognostic (3.14e-1)" "unprognostic (7.77e-2)" "unprognostic (2.04e-3)" "unprognostic (1.77e-1)" "unprognostic (3.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" 52.5 14.2 33.4 6.9 31.1 0.4 31.4 30.4 34.3 35.6 17.0 12.8 3.5 32.7 15.6 27.7 32.6 21.9 32.0 39.5 33.0 6.2 1.4 13.2 1.2 33.0 36.9 33.0 8.9 3.4 3.2 26.9 29.8 33.3 13.2 1.6 10.6 14.1 7.3 129.8 14.5 10.6 26.6 4.1 23.8 2.7 33.8 2.2 5.3 18.5 4.7 36.6 35.5 29.6 0.0 0.0 32.0 0.0 5.4 0.0 0.1 2.4 70.4 3.1 4.9 0.1 0.1 0.0 0.0 13.0 0.0 43.0 0.3 0.0 3.3 0.0 1.6 0.1 0.2 0.7 18.9 0.0 0.0 39.3 1.4 6.1 0.0 0.0 0.5 0.0 0.0 0.1 3.1 2.1 1.8 0.5 5.2 15.3 0.0 0.9 0.0 1.2 0.0 0.4 0.8 0.3 0.0 0.0 3.6 2.0 0.0 0.4 0.0 3.8 0.0 0.0 0.3 0.4 0.0 0.1 0.2 0.0 4.8 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.2 33.4 31.1 30.4 34.3 39.5 33.0 33.0 36.9 29.8 26.6 33.8 29.6 3.1 0.0 12.6 120.5 0.4 65.6 3.6 3.6 11.4 4.1 14.1 20.4 4.2 85.8 2.7 3.7 0.0 2.4 1.7 0.1 0.0 11.2 0.7 28.7 429.5 47.1 3.6 0.0 0.2 0.4 0.4 64.4 0.5 10.9 1.3 0.4 1.8 0.2 1.3 0.0 2.1 1.1 2.0 0.3 35.0 0.8 8.7 3.3 80.0 67.5 1.3 0.2 0.0 110.1 15.3 0.2 0.0 37.6 1.6 11.7 0.1 0.1 5.9 2.2 26.3 18.7 28.1 0.3 1.4 13.1 53.8 1.0 4.2 1.3 1.4 4.5 APCDD1L FLJ90166 ENSG00000198768 "APC down-regulated 1 like" Q8NCL9 20 58459101-58515399 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "salivary gland: 19.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 9.1;Breast myoepithelial cells: 7.7;Fibroblasts: 3.6;Oligodendrocyte precursor cells: 6.0;Skeletal myocytes: 8.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 94.5;hTEC/SVTERT24-B: 32.7;HUVEC TERT2: 33.6;TIME: 56.1;U-87 MG: 36.5" "Not detected" "Not detected" HPA067015 Uncertain Uncertain Mitochondria No No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA067015: AB_2685764" "unprognostic (2.61e-1)" "unprognostic (8.26e-3)" "unprognostic (4.63e-3)" "unprognostic (1.35e-5)" "unprognostic (4.09e-3)" "unprognostic (9.73e-3)" "unprognostic (1.31e-3)" "unprognostic (1.06e-4)" "unprognostic (7.63e-4)" "unprognostic (2.14e-2)" "unprognostic (7.62e-3)" "unprognostic (2.16e-1)" "unprognostic (6.55e-13)" "unprognostic (5.01e-3)" "unprognostic (3.21e-1)" "unprognostic (2.24e-2)" "unprognostic (1.81e-3)" 0.4 0.4 0.2 0.2 0.0 0.0 4.8 0.5 0.1 1.7 0.0 1.0 0.1 1.8 0.0 0.5 0.0 0.7 1.4 0.1 0.0 2.9 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.4 0.1 0.0 0.5 0.6 0.0 19.2 1.3 0.6 0.8 0.4 0.6 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 4.4 0.6 0.0 0.0 0.0 0.0 0.0 0.4 3.1 0.0 16.8 0.1 1.9 1.4 0.0 5.6 0.0 0.0 94.5 0.5 1.1 0.0 3.3 3.3 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 2.6 0.0 32.7 0.5 6.8 33.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 56.1 12.6 0.9 0.0 16.5 0.0 0.0 0.0 36.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.0 0.1 0.0 0.3 0.4 0.0 0.0 9.1 7.7 0.9 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.7 0.0 0.0 3.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 6.0 0.5 0.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 8.4 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 APPL2 "DIP13B, FLJ10659" ENSG00000136044 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2" Q8NEU8 12 105173297-105236203 "Disease related genes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 171.2;Microglial cells: 112.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 177.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039688, HPA043925" Approved NA NA 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA039688: AB_2676626, HPA043925: AB_2678733" "unprognostic (3.46e-1)" "unprognostic (4.21e-1)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.54e-2)" "unprognostic (2.41e-2)" "unprognostic (6.66e-3)" "unprognostic (8.43e-2)" "unprognostic (5.50e-2)" "unprognostic (5.71e-3)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "prognostic favorable (7.65e-4)" "unprognostic (1.87e-1)" "unprognostic (9.71e-2)" "unprognostic (1.86e-1)" "unprognostic (9.32e-2)" 34.1 29.2 33.1 18.5 35.9 37.0 35.2 41.0 35.5 33.0 29.8 54.1 38.8 26.3 19.0 23.4 20.7 34.4 16.3 30.6 34.6 20.7 16.1 18.4 22.7 36.5 34.4 28.8 23.8 23.2 19.7 23.1 37.7 38.8 54.7 33.5 22.2 26.9 14.5 66.6 57.6 22.1 33.0 22.9 31.7 36.6 36.5 20.0 16.2 12.8 17.7 16.6 27.8 38.6 15.5 23.2 37.8 22.9 111.9 80.5 27.6 114.4 110.1 40.0 24.3 27.7 11.8 13.5 21.6 177.9 15.3 18.1 19.2 24.6 49.0 6.8 16.6 7.4 11.4 12.4 18.1 5.5 7.4 42.6 22.9 31.6 35.4 77.4 17.2 18.2 8.4 17.5 90.9 20.9 10.6 17.6 27.8 33.1 33.1 8.3 24.9 25.3 33.4 31.9 25.7 48.1 38.4 17.0 19.3 26.6 28.3 10.1 16.7 61.7 14.8 30.4 19.4 15.9 13.7 9.9 39.6 7.3 34.4 0.2 4.7 10.7 1.6 3.7 1.3 0.4 0.6 0.9 3.2 2.8 0.9 1.4 21.1 4.6 6.2 1.0 2.3 1.7 33.1 35.9 41.0 35.5 30.6 34.6 36.5 34.4 37.7 33.0 36.5 38.6 16.0 19.2 13.2 95.3 6.1 12.7 13.0 6.5 12.0 30.6 18.0 14.1 13.2 28.6 10.6 11.0 10.4 19.9 12.1 171.2 5.9 24.2 6.8 33.8 23.0 15.7 30.0 2.5 50.2 18.9 19.0 22.8 15.8 20.7 8.2 46.0 16.4 6.5 30.3 10.1 51.8 40.0 12.2 23.3 8.3 8.6 23.6 18.9 16.0 112.4 10.3 39.9 10.3 91.5 75.1 26.4 38.1 21.8 6.0 29.4 101.5 16.6 56.2 16.2 19.7 18.9 13.2 15.6 23.7 14.3 19.0 23.1 8.0 25.0 17.5 14.2 ARF4 ARF2 ENSG00000168374 "ADP ribosylation factor 4" P18085 3 57571363-57598220 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 3100000 "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-1)" "unprognostic (2.11e-2)" "unprognostic (8.22e-2)" "unprognostic (1.17e-1)" "unprognostic (2.32e-1)" "unprognostic (6.81e-2)" "prognostic unfavorable (7.29e-7)" "unprognostic (4.78e-1)" "unprognostic (1.14e-1)" "unprognostic (1.24e-2)" "unprognostic (1.76e-2)" "unprognostic (2.47e-2)" "unprognostic (4.22e-2)" "unprognostic (3.56e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.30e-4)" "unprognostic (4.98e-3)" 128.5 162.7 53.5 107.4 56.5 72.6 138.4 56.5 73.3 208.7 75.3 158.9 123.5 121.7 226.7 108.9 96.1 154.8 116.5 56.8 64.5 114.4 172.6 126.3 73.9 57.4 62.3 113.5 151.2 101.5 105.8 181.8 59.6 138.5 197.2 54.0 182.1 132.8 64.8 67.3 109.2 169.2 61.6 66.5 130.9 100.8 58.6 74.9 143.9 69.5 97.3 203.6 91.4 63.6 251.8 90.4 218.5 182.1 516.7 533.3 212.8 617.9 585.5 382.0 483.4 264.4 235.0 89.2 110.3 774.3 334.8 95.4 234.0 353.1 491.3 111.7 76.9 183.4 196.6 351.3 647.1 115.7 127.8 517.3 308.8 355.4 423.8 482.6 480.1 86.8 134.5 173.8 672.8 123.1 69.7 146.8 263.8 333.5 306.5 40.7 173.3 170.5 459.6 175.8 67.5 164.1 252.9 240.1 325.0 298.5 167.9 193.4 369.8 299.8 174.9 447.9 360.6 126.3 116.3 124.0 331.4 220.8 378.3 249.4 85.3 95.4 41.1 72.8 72.2 53.2 58.3 53.5 72.3 48.1 71.4 55.5 102.8 58.2 65.9 109.2 59.9 90.8 53.5 56.5 56.5 73.3 56.8 64.5 57.4 62.3 59.6 61.6 58.6 63.6 172.5 76.9 90.8 18.3 150.2 350.1 505.9 429.6 195.8 32.2 249.8 204.7 48.4 91.5 259.6 97.5 6.2 322.3 146.7 226.5 191.7 287.1 179.1 195.5 197.2 146.5 164.5 232.4 25.2 232.6 448.2 298.4 200.3 301.4 101.7 121.8 101.7 161.0 197.2 18.5 26.9 403.7 248.2 90.1 264.9 72.6 177.0 139.4 241.9 15.9 112.8 156.2 35.0 30.2 30.2 396.8 238.1 185.8 346.8 399.6 180.8 178.5 201.2 27.2 78.9 115.1 345.5 132.4 80.7 188.2 321.9 698.2 133.0 230.4 272.3 599.7 ARHGAP22 RhoGAP2 ENSG00000128805 "Rho GTPase activating protein 22" Q7Z5H3 10 48446036-48656265 "Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell type enhanced" "Detected in many" "Late spermatids: 122.7;Microglial cells: 227.7;Oligodendrocyte precursor cells: 141.8;Oligodendrocytes: 200.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 68.8;LHCN-M2: 64.8;TIME: 66.2;U-87 MG: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020696, HPA040391, HPA064439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB020696: , HPA040391: AB_2676957, HPA064439: AB_2685266" "unprognostic (1.87e-1)" "unprognostic (3.98e-2)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.07e-1)" "unprognostic (6.74e-3)" "unprognostic (4.81e-3)" "unprognostic (2.78e-1)" "unprognostic (1.66e-1)" "unprognostic (3.03e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.16e-8)" "unprognostic (7.40e-2)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (3.66e-2)" 2.6 1.9 12.0 3.0 15.7 1.4 1.6 17.6 14.5 1.6 7.7 2.0 0.6 1.1 0.7 1.4 1.8 1.8 4.4 11.9 12.7 1.3 0.8 2.0 2.7 22.6 17.0 4.8 1.7 0.9 2.0 0.8 20.1 3.3 1.0 0.4 2.0 1.1 1.9 2.2 1.6 1.4 16.9 2.8 1.2 4.8 17.0 2.8 6.6 1.6 2.2 2.1 2.2 22.2 6.2 1.4 0.4 0.0 5.1 20.8 4.3 31.9 15.1 3.0 4.1 7.0 0.9 0.0 1.2 13.1 2.1 12.4 0.4 11.2 5.4 0.6 11.5 18.2 0.2 0.1 2.7 2.0 2.0 5.0 11.2 37.1 3.0 68.8 20.6 0.0 17.4 3.0 64.8 0.2 0.2 0.1 7.2 0.0 0.5 0.1 0.0 7.9 6.5 0.7 1.1 6.4 1.5 0.1 0.6 0.6 0.4 0.3 66.2 30.1 0.4 3.8 23.8 0.0 0.0 0.0 82.5 0.3 4.9 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 12.0 15.7 17.6 14.5 11.9 12.7 22.6 17.0 20.1 16.9 17.0 22.2 0.9 0.0 1.7 4.2 2.9 3.4 4.1 6.8 4.6 1.1 0.8 3.0 2.9 1.5 2.9 0.0 2.1 11.6 3.2 0.2 0.0 2.8 53.6 0.7 1.6 2.4 0.0 10.9 51.7 4.4 0.7 6.5 0.5 1.0 0.0 4.4 1.8 0.0 10.3 0.0 29.8 0.3 2.0 7.6 14.2 122.7 2.8 15.6 1.8 227.7 14.8 1.8 0.0 141.8 200.8 2.5 0.0 6.0 0.5 1.9 0.0 0.2 3.8 1.4 0.0 1.6 4.2 1.6 4.3 0.4 0.6 1.0 0.7 10.6 0.1 0.6 ARHGAP29 PARG1 ENSG00000137962 "Rho GTPase activating protein 29" Q52LW3 1 94148988-94275068 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 440.8;Endothelial cells: 298.6;Prostatic glandular cells: 593.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 12 "monocytes: 1.1" "Cell line enhanced" "Detected in many" "A-431: 118.8;hTERT-HME1: 100.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026534 Approved Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Centrosome" "Plasma membrane, Cytosol" "HPA026534: AB_1844998" "unprognostic (2.49e-1)" "unprognostic (1.52e-3)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (8.53e-2)" "unprognostic (2.94e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.63e-4)" "unprognostic (4.42e-1)" "unprognostic (2.36e-2)" "unprognostic (3.81e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (4.61e-3)" 32.9 3.7 7.0 2.8 5.5 0.1 30.3 22.5 8.0 8.8 7.3 9.4 2.1 7.4 5.3 4.5 10.2 6.5 19.2 4.6 5.5 23.7 16.8 27.1 4.9 6.8 6.1 10.2 7.4 6.5 6.2 17.4 7.1 11.2 3.2 14.9 12.1 7.0 11.6 14.7 6.4 5.6 6.4 21.7 10.4 5.8 8.6 3.0 22.8 12.7 2.8 8.0 9.3 5.1 118.8 4.8 7.0 0.1 26.7 57.5 24.5 38.6 62.9 31.0 45.1 13.7 5.4 0.0 85.2 76.5 36.3 24.8 0.2 27.4 63.9 0.1 4.1 0.4 6.6 7.6 2.7 0.0 0.0 11.7 5.4 23.7 100.9 36.4 88.0 0.1 0.0 0.0 32.1 4.7 2.2 0.1 9.0 0.6 82.1 1.4 5.6 0.0 82.7 10.8 0.1 1.5 24.1 20.5 2.0 26.5 5.6 0.4 84.2 20.0 26.2 29.7 32.3 0.1 0.1 0.2 3.7 0.0 0.9 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 7.0 5.5 22.5 8.0 4.6 5.5 6.8 6.1 7.1 6.4 8.6 5.1 440.8 51.3 18.4 26.4 2.9 23.5 239.2 31.7 4.6 16.0 87.3 46.1 26.0 31.5 39.6 130.6 18.8 29.5 2.0 0.9 54.8 83.5 94.1 36.9 11.4 298.6 0.0 3.2 11.3 17.2 102.6 63.6 20.9 106.2 3.8 13.8 177.1 56.1 3.0 92.5 24.1 1.0 6.1 13.6 17.9 24.4 24.5 6.2 26.6 208.9 2.5 94.2 0.0 2.0 3.5 55.7 0.1 21.8 0.1 593.9 0.1 78.1 12.5 81.2 190.7 58.2 127.8 80.3 116.5 1.7 17.2 14.1 4.1 11.1 1.6 146.9 ARID5B "FLJ21150, MRF2" ENSG00000150347 "AT-rich interaction domain 5B" Q14865 10 61901684-62096944 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 87.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 968.2;Syncytiotrophoblasts: 920.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 115.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015037 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Cytosol" "HPA015037: AB_1845015" "unprognostic (3.31e-1)" "unprognostic (1.99e-2)" "unprognostic (2.94e-2)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (5.60e-2)" "unprognostic (1.50e-2)" "unprognostic (4.90e-2)" "unprognostic (3.90e-1)" "unprognostic (6.03e-2)" "unprognostic (1.97e-1)" "unprognostic (5.75e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (2.58e-1)" "unprognostic (1.94e-1)" "unprognostic (3.93e-2)" 50.0 8.1 2.9 21.2 5.8 6.9 34.3 3.2 11.3 37.2 20.7 17.5 10.2 39.0 4.6 20.2 20.6 39.3 18.3 4.4 1.6 21.4 8.3 18.3 18.8 7.8 6.9 17.5 6.2 13.3 10.0 21.0 11.4 18.3 11.7 4.1 15.8 10.2 87.2 18.1 14.2 42.5 0.9 16.9 11.5 6.9 9.0 13.1 7.8 11.9 16.7 30.9 19.6 9.7 2.2 0.9 6.0 14.7 13.0 34.0 1.2 42.9 115.2 29.9 23.3 52.7 2.3 3.9 10.1 41.4 4.3 14.3 20.6 6.5 36.0 13.7 6.1 2.1 10.4 13.5 23.9 0.6 25.2 43.3 3.4 17.6 20.2 26.2 3.9 7.5 1.9 5.7 9.9 7.7 14.4 1.1 1.1 10.2 13.5 17.7 9.8 1.1 20.1 23.9 3.3 4.4 19.2 10.6 12.8 13.1 8.7 0.7 3.3 16.5 22.0 25.1 10.9 0.4 0.0 11.4 14.3 0.8 5.4 9.6 1.2 0.8 13.3 2.8 1.8 37.5 19.7 11.8 2.2 41.2 12.8 8.4 2.2 12.3 8.2 1.0 30.9 5.4 2.9 5.8 3.2 11.3 4.4 1.6 7.8 6.9 11.4 0.9 9.0 9.7 86.2 131.4 70.7 54.5 199.8 968.2 453.9 111.3 105.9 54.4 112.8 96.6 72.8 27.1 96.3 51.5 0.0 187.8 89.1 7.5 99.7 56.1 31.7 164.7 231.0 134.1 36.4 5.2 167.8 14.6 150.7 343.6 21.4 457.7 24.6 37.6 119.2 7.4 51.0 74.0 181.9 18.7 22.4 44.1 162.4 20.1 151.6 43.6 138.7 34.7 39.0 17.2 58.7 74.4 155.8 41.1 25.2 60.5 234.5 193.7 5.4 304.8 38.4 3.6 131.5 496.3 463.9 8.2 5.8 65.7 477.8 920.4 178.2 24.3 41.7 233.9 ARL1 ARFL1 ENSG00000120805 "ADP ribosylation factor like GTPase 1" P40616 12 101393116-101407772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062656, HPA073012" Approved Supported "Golgi apparatus" NA NA 13000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 1: Thyroid gland - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA062656: AB_2684821, HPA073012: AB_2686564" "unprognostic (5.52e-2)" "unprognostic (1.90e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.61e-4)" "unprognostic (6.41e-2)" "unprognostic (3.15e-2)" "unprognostic (2.62e-3)" "unprognostic (1.69e-1)" "unprognostic (1.97e-1)" "unprognostic (4.82e-2)" "unprognostic (2.28e-1)" "unprognostic (4.54e-2)" "unprognostic (1.04e-2)" "unprognostic (1.21e-1)" "unprognostic (1.74e-1)" "unprognostic (6.22e-2)" "unprognostic (3.46e-2)" 46.4 66.0 25.3 40.0 27.0 16.5 62.5 26.6 31.6 86.5 41.8 56.6 48.0 51.3 71.2 49.1 50.1 43.6 65.5 27.1 33.6 76.6 68.6 36.6 33.2 30.1 29.3 65.2 44.6 92.6 59.1 51.5 31.9 73.4 60.5 48.7 73.9 69.1 51.9 27.8 43.2 59.7 28.5 28.9 57.5 32.8 28.0 32.8 84.7 56.7 48.7 53.0 35.9 27.7 64.9 61.2 58.8 51.6 162.0 161.5 77.8 129.2 155.2 85.9 81.9 71.4 46.9 58.4 77.3 150.7 76.4 44.3 67.1 88.6 98.0 47.0 51.5 54.9 32.9 110.7 120.2 63.7 40.2 97.7 77.1 85.6 135.7 146.1 93.1 39.7 74.1 33.5 113.3 76.1 55.4 63.4 56.6 93.9 82.5 40.8 58.8 67.1 130.5 128.6 38.8 25.5 62.1 80.5 104.2 82.6 136.0 43.5 70.4 65.1 37.3 88.5 56.4 55.5 59.5 58.9 93.3 47.4 71.5 50.4 25.3 18.2 21.8 30.7 32.5 30.1 25.8 28.4 32.8 28.8 25.6 20.1 2.5 23.7 34.2 39.6 34.1 24.6 25.3 27.0 26.6 31.6 27.1 33.6 30.1 29.3 31.9 28.5 28.0 27.7 57.0 41.7 46.7 13.4 39.4 51.2 71.4 175.5 38.7 42.1 65.1 64.4 75.2 41.5 119.1 69.9 18.8 102.6 30.5 42.3 125.2 97.0 90.2 54.8 68.4 44.6 47.5 24.6 14.5 64.3 119.4 88.4 36.2 60.6 37.4 37.4 36.8 50.2 65.8 32.0 19.5 125.6 75.3 27.7 31.9 31.8 78.6 31.6 55.2 6.5 39.6 81.9 25.7 12.5 15.8 62.1 52.2 71.1 79.3 117.2 70.4 131.3 100.0 48.9 46.0 51.2 75.7 134.6 86.1 46.2 55.4 135.3 28.8 54.6 65.7 100.1 ARMCX4 "CXorf35, GASP4, MGC40053" ENSG00000196440 "Armadillo repeat containing X-linked 4" Q5H9R4 X 101418287-101533459 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 66.6;Excitatory neurons: 59.1;Inhibitory neurons: 87.5;Microglial cells: 63.7;Oligodendrocyte precursor cells: 78.4;Oligodendrocytes: 75.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000429, HPA051930" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Vesicles "HPA000429: AB_1078210, HPA051930: AB_2681665" "unprognostic (1.92e-1)" "unprognostic (1.91e-1)" "unprognostic (1.07e-2)" "unprognostic (1.10e-2)" "unprognostic (6.91e-3)" "unprognostic (2.81e-3)" "unprognostic (7.28e-2)" "unprognostic (3.67e-4)" "unprognostic (2.33e-2)" "unprognostic (4.29e-1)" "prognostic favorable (8.20e-5)" "unprognostic (1.94e-2)" "unprognostic (1.40e-2)" "unprognostic (6.94e-3)" "unprognostic (1.69e-1)" "unprognostic (1.88e-1)" "unprognostic (4.92e-2)" 2.1 4.0 1.8 1.1 2.1 0.7 2.7 1.4 2.0 2.8 0.0 2.5 0.9 3.6 2.5 1.0 3.0 1.3 1.8 2.0 3.0 2.4 1.0 1.8 0.9 1.8 2.1 7.1 2.0 4.5 4.5 1.7 2.1 3.6 1.6 1.6 1.9 4.7 1.9 2.1 2.1 2.6 1.1 1.7 1.8 0.9 2.2 0.9 2.7 1.0 0.8 2.3 1.8 2.3 2.4 0.6 7.9 0.0 3.7 3.9 0.8 5.5 4.3 4.4 8.5 1.9 0.7 0.0 2.1 8.2 0.1 0.9 0.0 0.1 7.2 0.0 0.9 0.6 2.5 0.0 2.2 0.0 3.0 2.4 0.4 9.6 0.0 0.0 7.8 0.0 0.0 0.7 2.0 0.0 0.3 0.3 5.8 0.8 0.0 0.4 6.5 0.0 1.1 1.4 5.3 4.9 0.8 0.0 3.0 1.3 0.6 1.2 2.9 2.0 1.2 6.1 0.0 0.0 0.0 0.0 3.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.1 1.4 2.0 2.0 3.0 1.8 2.1 2.1 1.1 2.2 2.3 8.7 3.2 6.8 66.6 2.2 2.4 7.7 1.7 5.7 24.5 9.1 7.1 10.5 2.8 7.9 27.6 8.4 1.7 2.6 2.3 17.6 2.7 0.2 5.6 8.9 8.0 3.0 1.3 59.1 2.3 0.7 11.0 2.0 8.3 3.8 13.3 5.3 2.5 2.3 23.5 87.5 2.3 6.1 3.8 5.1 0.7 10.5 2.4 17.8 63.7 2.8 11.6 4.1 78.4 75.6 2.0 3.9 12.4 2.2 5.3 4.7 4.8 9.8 7.8 0.0 8.1 10.9 1.3 1.3 1.8 3.4 1.5 2.2 8.4 4.0 4.5 ARNT2 "bHLHe1, KIAA0307" ENSG00000172379 "Aryl hydrocarbon receptor nuclear translocator 2" Q9HBZ2 15 80404350-80597933 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 128.0" "Group enriched" "Detected in many" 4 "Astrocytes: 209.6;Excitatory neurons: 204.7;Inhibitory neurons: 301.5;Microglial cells: 98.4;Oligodendrocyte precursor cells: 232.7;Oligodendrocytes: 136.9" "Cancer enhanced" "Detected in all" "glioma: 27.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 28.4;BJ hTERT+ SV40 Large T+ RasG12V: 28.2;hTERT-RPE1: 29.7;LHCN-M2: 26.0;SK-MEL-30: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001056, CAB005081" Enhanced Supported Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB005081: AB_2243005, HPA001056: AB_1845042" "unprognostic (2.04e-3)" "unprognostic (8.32e-2)" "unprognostic (2.10e-1)" "unprognostic (1.95e-1)" "unprognostic (1.11e-1)" "unprognostic (5.65e-2)" "unprognostic (2.61e-2)" "unprognostic (1.48e-1)" "unprognostic (2.74e-2)" "unprognostic (3.00e-1)" "prognostic favorable (1.46e-6)" "unprognostic (2.20e-1)" "prognostic favorable (7.51e-4)" "unprognostic (2.53e-1)" "unprognostic (2.31e-1)" "unprognostic (3.39e-1)" "unprognostic (3.62e-2)" 2.2 2.1 94.4 2.1 100.6 0.4 1.4 47.8 111.7 5.6 29.8 5.8 1.7 5.9 8.2 2.0 5.3 2.5 4.1 128.0 64.2 21.7 0.4 5.0 2.3 61.8 70.5 10.7 3.4 6.4 11.5 1.1 53.6 5.5 2.1 8.1 1.2 5.0 9.7 2.1 2.7 3.9 60.2 3.5 4.1 9.9 84.0 2.2 7.0 6.0 3.0 4.3 2.0 66.7 0.4 16.1 28.4 0.0 0.1 3.6 0.1 12.2 17.3 13.9 28.2 0.0 0.0 0.0 3.0 14.7 7.2 0.4 10.5 0.6 17.7 0.0 2.9 0.5 0.0 1.0 0.9 0.0 7.2 13.2 0.5 6.1 0.3 29.7 0.0 0.0 0.0 0.1 26.0 14.0 0.0 0.0 5.7 0.0 0.2 0.0 0.3 0.0 6.0 20.5 14.9 20.6 1.5 0.2 30.8 1.8 0.6 0.0 0.0 22.2 4.4 0.6 14.7 0.0 0.0 0.0 8.4 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.4 100.6 47.8 111.7 128.0 64.2 61.8 70.5 53.6 60.2 84.0 66.7 0.1 0.0 2.3 209.6 0.0 1.3 1.2 1.5 4.0 17.0 3.2 3.4 7.6 2.8 4.7 3.7 8.4 0.2 0.1 0.2 13.7 6.0 36.7 8.5 2.7 1.8 22.9 0.0 204.7 0.2 3.6 2.7 3.1 4.4 2.5 5.7 0.4 0.0 0.2 1.7 301.5 2.6 8.2 0.0 1.6 39.8 0.6 0.4 7.2 98.4 0.1 5.9 2.1 232.7 136.9 2.4 2.3 3.0 0.0 2.2 0.3 1.0 1.6 9.3 6.6 2.6 2.5 2.1 3.0 0.5 0.3 2.7 0.6 1.9 1.3 1.4 ARPC5 "ARC16, dJ127C7.3, p16-Arc" ENSG00000162704 "Actin related protein 2/3 complex subunit 5" O15511 1 183620846-183635783 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022013, HPA031972" Approved Approved "Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA 3300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Plasma membrane, Cell Junctions, Cytosol" "HPA022013: AB_1845045, HPA031972: " "unprognostic (3.82e-1)" "unprognostic (8.78e-2)" "unprognostic (1.43e-1)" "unprognostic (2.36e-2)" "unprognostic (1.74e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (5.90e-3)" "unprognostic (3.84e-2)" "unprognostic (3.17e-3)" "unprognostic (1.14e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.21e-10)" "unprognostic (3.03e-2)" "unprognostic (4.66e-2)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" 86.1 49.2 17.4 148.2 22.5 69.1 48.8 23.7 23.8 46.5 13.0 104.7 99.5 69.5 15.7 77.8 52.0 52.9 35.7 20.0 22.3 39.0 64.3 103.1 158.9 35.2 22.8 30.6 51.7 29.9 19.7 108.2 29.7 46.0 68.9 8.0 45.9 35.9 18.7 42.6 117.4 78.9 24.0 120.8 88.6 38.4 24.1 130.5 46.0 22.5 131.3 75.9 51.8 37.8 313.4 167.7 141.0 98.1 114.0 161.5 338.7 419.7 317.9 176.3 143.0 150.9 215.9 284.9 463.9 241.7 114.6 211.2 101.1 141.6 93.9 413.6 87.1 172.9 212.6 132.6 185.2 254.8 325.0 197.6 148.2 215.7 170.3 201.2 213.7 196.1 133.3 229.1 233.9 125.6 238.5 67.9 133.7 238.5 63.0 219.2 126.3 278.6 97.3 158.7 61.1 164.7 435.8 186.1 167.3 147.1 185.2 222.5 480.9 259.0 134.5 293.8 410.1 270.1 321.8 196.2 204.5 179.6 204.6 1221.0 987.7 1563.7 395.7 1110.1 315.7 338.3 382.3 407.1 838.9 339.7 409.4 415.4 1852.1 392.6 1267.7 394.3 512.4 1913.3 17.4 22.5 23.7 23.8 20.0 22.3 35.2 22.8 29.7 24.0 24.1 37.8 148.7 375.0 188.9 8.1 163.3 249.1 178.3 275.9 91.0 34.2 79.9 118.9 30.2 150.2 197.6 82.8 14.6 475.1 227.4 283.5 166.3 344.3 35.5 78.8 211.4 186.7 202.0 90.0 21.6 280.2 734.2 166.2 87.1 119.8 258.8 147.7 181.7 87.4 608.5 38.7 13.8 146.6 238.0 556.3 740.8 24.2 125.9 558.5 254.3 20.6 635.1 56.7 423.3 7.5 51.5 381.6 234.5 183.6 132.1 182.6 213.6 152.0 95.2 25.4 243.3 83.9 286.8 151.9 137.3 161.5 244.9 199.5 234.4 144.4 155.4 234.6 ARSJ FLJ23548 ENSG00000180801 "Arylsulfatase family member J" Q5FYB0 4 113900284-113979727 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 35.3;Astrocytes: 44.1;Basal prostatic cells: 60.3;Prostatic glandular cells: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 46.4;HUVEC TERT2: 42.2;LHCN-M2: 42.8;TIME: 53.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036481, HPA036482" Uncertain Enhanced "Actin filaments" "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "HPA036481: AB_2675146, HPA036482: AB_10672356" "unprognostic (1.98e-1)" "unprognostic (1.55e-2)" "unprognostic (4.23e-1)" "unprognostic (5.31e-1)" "unprognostic (6.23e-2)" "prognostic unfavorable (6.08e-4)" "unprognostic (2.54e-2)" "unprognostic (2.49e-2)" "unprognostic (1.60e-1)" "unprognostic (1.04e-1)" "unprognostic (5.31e-2)" "unprognostic (2.20e-1)" "prognostic favorable (2.97e-6)" "unprognostic (2.26e-1)" "unprognostic (8.37e-2)" "unprognostic (1.30e-1)" "unprognostic (2.07e-2)" 1.8 1.3 1.5 1.3 1.1 0.0 1.0 5.0 1.4 4.5 0.2 2.4 0.6 2.0 0.9 3.1 2.8 3.6 2.5 1.2 0.9 2.7 1.7 3.3 0.6 0.9 1.1 2.0 1.1 3.0 0.7 4.3 0.7 3.9 3.3 0.6 5.8 2.2 0.2 0.7 0.7 2.2 0.6 0.2 3.5 0.1 1.9 1.5 0.7 0.6 0.3 3.8 2.1 1.1 2.7 5.3 0.6 0.0 10.1 20.5 0.0 46.4 35.5 29.0 11.3 1.3 3.4 0.0 5.7 22.6 10.3 5.0 0.2 11.7 36.2 0.0 2.1 0.0 4.2 0.0 30.6 0.0 0.0 12.7 11.5 19.7 40.0 20.5 42.2 0.0 0.0 0.0 42.8 0.4 0.0 0.0 1.5 0.0 8.4 0.0 5.1 0.0 38.0 0.0 0.0 1.7 3.1 0.5 2.2 7.5 0.2 0.0 53.6 33.3 8.7 5.0 22.3 0.0 0.0 0.0 16.2 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 5.0 1.4 1.2 0.9 0.9 1.1 0.7 0.6 1.9 1.1 0.7 35.3 9.8 44.1 0.2 2.9 60.3 23.7 15.9 0.2 4.7 2.9 1.3 11.5 10.8 25.8 0.0 0.3 0.1 7.0 0.0 9.2 0.0 6.2 21.1 4.3 23.4 0.0 27.1 0.9 0.2 13.6 4.6 8.2 0.0 0.0 4.2 1.2 0.5 1.7 1.5 17.3 16.2 0.3 1.6 0.3 2.5 0.3 3.6 7.5 0.0 6.8 1.0 3.0 0.5 5.2 5.0 1.5 0.0 49.6 0.1 4.1 4.6 0.2 0.0 8.6 10.5 0.1 0.3 16.9 1.1 0.4 0.6 3.3 4.1 25.6 ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 345.8;Late spermatids: 460.2;Oligodendrocyte precursor cells: 622.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.6" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.6;monocytes: 6.7" "Cell line enhanced" "Detected in all" "TIME: 167.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565" Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA 31000 "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome, Cytosol" "CAB037292: AB_476723, HPA011136: AB_2668438, HPA048565: AB_2680445" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.77e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.63e-8)" "prognostic unfavorable (3.56e-5)" "unprognostic (3.34e-1)" "unprognostic (5.27e-2)" "unprognostic (8.56e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (3.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.38e-2)" "unprognostic (1.22e-3)" 35.1 22.2 13.5 12.2 15.1 47.8 24.0 7.6 22.0 17.6 3.9 13.4 5.5 19.0 12.2 10.7 17.2 14.6 24.7 14.7 10.5 11.9 9.3 30.1 18.0 14.2 20.9 18.2 7.8 18.1 10.5 27.8 16.5 12.7 8.9 8.6 8.5 11.4 13.4 17.3 12.2 17.9 9.4 30.0 10.6 28.5 29.1 16.3 16.4 10.4 19.0 15.9 15.6 17.1 48.9 31.5 41.1 27.4 46.7 61.9 37.1 44.2 83.8 57.2 62.3 17.5 18.2 14.4 31.8 67.7 38.6 13.2 24.7 41.4 86.3 20.6 15.9 22.6 20.7 23.6 119.9 10.4 6.7 61.7 15.3 33.6 50.3 66.9 60.2 7.7 13.0 45.7 54.0 15.1 13.3 9.8 13.1 24.1 30.5 13.6 9.6 7.0 18.1 25.2 14.6 44.4 32.4 20.5 26.5 42.5 17.0 22.4 167.5 45.9 28.9 20.6 69.8 42.2 12.0 9.7 34.6 14.6 50.3 0.0 2.2 1.5 0.5 2.1 0.3 1.3 1.0 0.9 3.7 1.0 1.3 0.8 11.6 0.6 6.7 0.4 0.8 1.1 13.5 15.1 7.6 22.0 14.7 10.5 14.2 20.9 16.5 9.4 29.1 17.1 97.2 3.2 6.3 206.6 22.7 47.7 21.9 12.0 29.6 25.0 12.4 14.7 33.7 27.1 11.5 3.7 16.7 42.2 14.6 3.6 3.9 10.5 159.7 14.3 34.2 109.1 13.1 98.9 345.8 8.7 37.6 43.7 4.6 27.7 9.5 30.1 103.9 8.2 64.0 62.2 225.8 4.3 8.2 56.1 168.8 460.2 39.1 73.1 44.4 181.8 71.4 9.5 15.5 622.3 245.9 12.5 4.7 54.9 13.7 37.9 5.8 4.3 4.2 7.8 78.9 28.5 90.1 61.4 95.5 25.2 44.9 46.7 23.1 58.9 4.8 22.0 ASCC3 "ASC1p200, dJ121G13.4, dJ467N11.1, HELIC1, RNAH" ENSG00000112249 "Activating signal cointegrator 1 complex subunit 3" Q8N3C0 6 100508194-100881372 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 166.0;Inhibitory neurons: 166.2;Oligodendrocyte precursor cells: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031608, HPA031609, HPA031610" Enhanced Supported "Golgi apparatus,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Golgi apparatus" "HPA031608: AB_10599970, HPA031609: AB_10600777, HPA031610: AB_10611526" "unprognostic (6.79e-2)" "unprognostic (1.46e-2)" "unprognostic (2.96e-3)" "unprognostic (1.12e-1)" "unprognostic (9.70e-3)" "unprognostic (4.56e-2)" "unprognostic (1.50e-1)" "unprognostic (5.14e-2)" "unprognostic (4.02e-1)" "unprognostic (3.34e-1)" "unprognostic (5.08e-3)" "unprognostic (1.16e-1)" "unprognostic (9.91e-2)" "unprognostic (1.90e-1)" "unprognostic (1.56e-1)" "unprognostic (1.01e-1)" "unprognostic (1.55e-2)" 6.0 6.6 4.1 10.0 5.3 11.2 9.2 6.6 4.2 10.2 7.7 9.3 8.2 7.9 8.5 8.4 5.8 7.5 6.5 3.9 5.2 5.0 12.5 7.1 10.1 4.7 4.3 5.9 6.4 10.7 6.2 12.9 5.1 9.2 11.3 5.7 6.3 8.1 6.0 7.2 8.5 8.5 4.7 8.3 8.6 8.6 4.6 12.7 7.2 5.4 11.0 14.8 7.4 6.0 16.8 21.1 30.1 18.6 32.9 41.7 48.0 71.5 45.5 24.1 27.6 43.3 13.0 52.1 14.4 48.3 19.0 37.6 26.2 63.5 38.7 35.2 23.2 38.7 36.0 27.8 30.1 41.0 28.5 38.1 31.7 35.4 44.2 22.6 45.1 20.5 47.1 23.0 67.3 16.5 21.1 12.7 15.9 31.8 16.4 24.7 23.3 18.7 23.7 46.6 20.2 15.3 30.1 26.7 12.5 53.3 14.7 23.2 64.2 26.9 20.6 23.3 30.4 9.9 11.3 46.4 19.4 30.6 29.0 6.2 2.7 1.8 4.3 4.3 5.2 4.2 3.8 4.0 2.9 5.7 4.3 4.2 0.2 4.4 3.8 6.4 3.1 1.4 4.1 5.3 6.6 4.2 3.9 5.2 4.7 4.3 5.1 4.7 4.6 6.0 32.7 32.1 24.9 58.1 45.4 25.5 41.3 33.3 19.4 27.0 24.1 24.0 32.0 20.0 37.7 3.7 22.9 24.4 49.0 17.3 11.7 23.1 11.3 30.1 77.3 25.2 13.8 20.8 166.0 25.1 66.3 32.2 46.9 35.0 22.1 29.9 10.4 30.3 17.7 28.6 166.2 22.8 22.4 17.2 12.5 3.7 23.0 27.5 5.4 103.0 26.2 14.6 29.9 150.8 132.3 28.6 14.4 17.3 66.4 66.9 17.5 10.6 32.0 31.1 6.6 39.6 30.0 50.2 30.3 38.2 27.4 38.0 43.7 42.6 23.5 65.4 ATG7 "APG7L, DKFZp434N0735, GSA7" ENSG00000197548 "Autophagy related 7" O95352 3 11272309-11557665 "Predicted intracellular proteins, Transporters" "Autophagy, Biological rhythms, Protein transport, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 160.0;Excitatory neurons: 178.7;Inhibitory neurons: 176.4;Late spermatids: 119.1;Microglial cells: 132.1;Oligodendrocytes: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 60.1;classical monocyte: 136.6;eosinophil: 88.4;intermediate monocyte: 79.4;myeloid DC: 82.4;neutrophil: 107.4;non-classical monocyte: 60.8" "Group enriched" "Detected in all" 5 "dendritic cells: 82.4;granulocytes: 107.4;monocytes: 136.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007639, CAB018771" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 33000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Plasma membrane" "CAB018771: AB_2062165, HPA007639: AB_1845162" "unprognostic (3.97e-2)" "unprognostic (2.83e-2)" "prognostic favorable (9.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.79e-1)" "unprognostic (5.19e-2)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.82e-1)" "unprognostic (2.40e-1)" "unprognostic (1.80e-3)" "unprognostic (2.30e-2)" "unprognostic (2.67e-1)" "prognostic favorable (9.55e-4)" "unprognostic (1.61e-1)" "unprognostic (3.65e-2)" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" 16.8 13.5 11.2 25.0 13.1 47.6 18.0 7.3 21.8 14.5 17.0 17.3 13.0 14.9 16.7 16.7 18.7 16.6 10.8 12.4 9.5 13.7 13.2 20.9 23.9 15.0 15.0 12.2 10.9 21.2 7.5 21.0 13.1 11.6 19.2 10.3 12.2 11.9 13.0 18.0 13.8 20.0 12.4 16.4 14.4 22.5 15.4 13.1 13.0 13.5 25.0 20.3 12.0 21.3 48.5 37.1 16.7 9.2 28.0 36.7 80.4 44.5 56.8 43.1 49.9 16.0 42.5 22.1 26.5 39.2 45.1 14.5 18.3 62.0 73.8 19.8 23.5 16.0 33.6 19.6 36.9 46.8 50.8 38.0 28.2 83.6 52.0 45.4 60.5 14.0 24.1 17.9 60.6 31.3 13.7 21.3 13.0 22.2 47.9 17.1 19.6 19.9 32.5 34.2 14.6 14.5 31.6 26.4 17.5 20.1 28.8 44.7 42.5 36.0 25.7 23.6 63.2 11.1 31.8 38.1 57.8 43.1 49.9 60.1 136.6 88.4 15.9 79.4 12.3 13.0 12.9 15.1 82.4 12.3 11.7 13.7 107.4 21.3 60.8 14.7 12.4 56.8 11.2 13.1 7.3 21.8 12.4 9.5 15.0 15.0 13.1 12.4 15.4 21.3 6.4 0.0 9.8 160.0 11.4 11.1 7.3 21.6 9.6 18.1 7.4 3.6 4.2 4.3 12.5 7.3 18.8 16.5 7.9 8.3 7.9 12.3 44.2 10.6 9.5 14.6 11.4 9.5 178.7 12.9 16.8 11.0 10.7 13.2 14.7 12.4 19.6 9.0 57.6 20.2 176.4 7.6 22.4 25.8 12.1 119.1 10.2 28.8 3.6 132.1 30.6 8.1 13.4 99.0 137.2 17.4 7.3 9.8 10.8 6.4 8.4 6.8 16.5 12.5 6.6 11.7 10.6 22.4 11.9 9.8 7.7 19.2 10.1 9.9 7.6 7.4 ATP10A "ATP10C, ATPVA, ATPVC, KIAA0566" ENSG00000206190 "ATPase phospholipid transporting 10A (putative)" O60312 15 25677271-25865184 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0" "Cell type enriched" "Detected in many" 6 "Microglial cells: 216.4" "Cancer enhanced" "Detected in all" "melanoma: 7.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 23.0;fHDF/TERT166: 22.9;HMC-1: 19.4;SK-MEL-30: 21.9;U-2197: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041496, HPA042509" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041496: AB_2677513, HPA042509: AB_2678032" "unprognostic (3.70e-1)" "unprognostic (2.83e-2)" "unprognostic (2.30e-4)" "unprognostic (1.18e-1)" "unprognostic (9.46e-2)" "unprognostic (2.91e-2)" "unprognostic (2.67e-1)" "unprognostic (4.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" "unprognostic (4.89e-2)" "unprognostic (9.42e-2)" 6.5 8.7 13.7 2.7 9.3 2.5 5.3 6.0 8.9 2.0 0.7 3.2 0.8 1.5 0.1 1.9 2.3 3.7 2.0 5.9 5.8 5.8 0.6 7.1 1.8 9.9 9.7 1.1 1.4 3.5 2.1 1.7 9.5 2.2 0.8 0.1 7.9 0.6 0.6 2.5 3.0 2.8 5.9 1.5 3.2 4.3 15.0 1.1 2.5 0.7 1.1 2.5 1.4 4.9 0.0 5.7 1.3 0.0 2.2 2.8 0.0 23.0 9.3 6.1 9.9 0.0 0.0 0.0 1.6 22.9 0.0 0.0 9.3 1.2 0.4 0.0 0.2 0.0 0.0 0.1 0.1 0.0 19.4 0.9 0.0 0.6 0.0 2.5 0.0 1.2 0.0 0.0 3.3 0.0 1.2 0.0 1.5 0.0 1.5 4.4 4.6 2.8 9.9 0.0 0.0 0.1 0.0 0.0 21.9 0.0 7.4 1.2 0.0 8.9 0.2 12.7 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.3 0.5 0.1 0.0 0.7 0.6 0.0 1.2 0.0 1.0 0.1 0.3 13.7 9.3 6.0 8.9 5.9 5.8 9.9 9.7 9.5 5.9 15.0 4.9 0.3 32.1 8.6 2.0 0.8 1.0 0.0 2.7 0.6 0.2 2.6 1.8 1.7 1.5 5.3 0.0 0.0 0.0 11.1 0.1 0.0 0.5 23.2 2.8 2.8 4.2 0.0 0.0 4.5 0.0 0.1 5.0 3.1 7.9 15.2 0.0 0.4 0.1 2.5 0.0 2.1 0.2 0.0 2.5 5.2 21.8 4.1 4.5 17.8 216.4 2.3 0.0 14.4 1.5 2.7 0.8 0.0 17.7 1.7 0.7 0.0 0.1 4.2 0.1 0.0 4.7 9.1 0.4 1.2 0.0 0.4 0.0 8.6 0.1 0.0 0.0 ATP10D "ATPVD, KIAA1487" ENSG00000145246 "ATPase phospholipid transporting 10D (putative)" Q9P241 4 47485275-47593486 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 12 "basophil: 84.3" "Lineage enriched" "Detected in all" 12 "granulocytes: 84.3" "Cell line enhanced" "Detected in many" "HAP1: 41.6" "Low region specificity" "Detected in all" HPA050808 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Plasma membrane" "HPA050808: AB_2681242" "unprognostic (1.62e-1)" "unprognostic (2.97e-1)" "unprognostic (4.93e-2)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "unprognostic (4.23e-2)" "unprognostic (1.65e-2)" "unprognostic (8.05e-2)" "unprognostic (3.48e-2)" "unprognostic (3.54e-2)" "unprognostic (3.04e-1)" "unprognostic (2.43e-1)" "prognostic favorable (5.00e-8)" "unprognostic (3.97e-2)" "unprognostic (4.47e-3)" "unprognostic (1.11e-2)" "unprognostic (3.37e-2)" 4.9 6.0 2.6 5.0 2.9 1.3 4.2 1.9 2.7 7.0 15.9 3.7 3.9 7.4 7.2 10.2 4.7 7.4 4.2 1.8 4.1 10.2 2.4 6.1 6.2 3.1 3.7 8.1 4.5 10.4 3.1 14.9 2.9 4.6 3.8 4.1 3.4 6.4 1.0 9.9 4.5 9.7 2.4 10.0 5.1 2.0 5.0 4.5 9.1 2.7 7.9 7.3 6.5 2.9 2.6 1.8 4.0 2.8 11.1 12.0 0.7 17.9 21.5 8.4 15.1 9.4 15.4 8.1 6.5 29.1 14.3 4.6 41.6 15.0 12.9 3.2 3.2 6.5 2.8 0.5 9.8 2.1 3.9 10.3 11.2 16.4 10.9 27.5 14.4 4.0 0.1 4.3 23.2 1.0 4.4 1.2 1.4 0.0 2.2 4.9 9.0 0.1 15.0 3.1 2.6 4.9 8.4 2.1 5.2 8.7 3.8 2.1 21.9 20.7 4.1 1.9 7.8 1.9 1.5 0.0 10.2 11.9 6.8 84.3 3.1 0.4 1.1 5.0 1.9 2.7 0.5 0.8 4.0 6.7 0.1 0.9 1.5 2.3 6.9 2.4 0.8 1.6 2.6 2.9 1.9 2.7 1.8 4.1 3.1 3.7 2.9 2.4 5.0 2.9 22.9 9.6 7.5 39.2 27.8 19.2 9.2 21.9 23.9 12.2 6.7 8.4 4.9 4.3 8.5 16.5 31.3 48.5 17.1 1.6 1.9 5.5 4.4 4.8 29.5 16.1 9.6 4.0 25.7 4.6 11.0 22.4 14.3 7.0 2.5 21.3 18.2 6.6 13.0 13.5 42.8 4.6 18.3 21.7 7.9 1.5 62.1 17.7 7.2 47.8 15.7 21.9 15.5 52.3 24.1 2.7 3.4 25.2 23.0 5.7 1.9 9.2 6.2 9.2 26.3 12.8 23.6 0.6 2.8 35.4 27.0 176.8 15.5 51.7 4.1 8.1 ATP11C "ATPIG, ATPIQ" ENSG00000101974 "ATPase phospholipid transporting 11C" Q8NB49 X 139726346-139945276 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 49.8" "Cell type enhanced" "Detected in many" "Spermatocytes: 67.9" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030830 Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA030830: AB_10601336" "unprognostic (8.94e-2)" "unprognostic (1.00e-2)" "unprognostic (3.06e-2)" "unprognostic (3.42e-3)" "unprognostic (3.08e-1)" "unprognostic (3.46e-1)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (4.80e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (3.65e-2)" "unprognostic (9.75e-2)" "unprognostic (2.73e-1)" "unprognostic (5.18e-2)" 13.4 7.4 3.5 9.0 4.2 6.1 10.4 3.6 4.6 11.8 10.3 10.0 5.6 11.9 9.3 5.1 10.7 8.4 5.4 3.1 4.5 11.8 49.8 7.2 14.8 4.9 4.7 12.7 4.9 5.7 3.7 5.3 5.2 9.8 7.1 2.8 6.0 14.6 3.5 6.0 8.6 10.6 3.9 12.2 7.6 9.7 4.8 11.1 6.1 4.3 8.8 13.6 9.3 4.5 16.9 7.1 14.2 23.3 20.7 27.9 18.0 19.7 26.4 15.6 21.5 6.3 13.4 24.0 43.3 28.2 10.3 13.7 34.6 9.0 24.4 22.1 20.2 12.1 15.2 12.3 23.0 21.4 7.4 18.6 5.9 16.9 14.4 17.3 27.3 18.3 14.0 17.9 20.8 9.1 19.7 14.5 24.1 0.1 13.3 19.5 15.3 20.1 13.1 27.6 11.0 18.3 7.8 0.8 10.6 13.3 5.8 11.7 31.0 21.2 6.9 25.9 27.1 5.1 5.4 18.7 9.7 26.3 10.8 2.4 0.4 0.1 0.4 0.3 0.8 0.9 0.4 0.3 0.4 0.9 0.4 0.7 0.9 1.2 0.6 0.7 0.3 0.2 3.5 4.2 3.6 4.6 3.1 4.5 4.9 4.7 5.2 3.9 4.8 4.5 27.4 16.0 8.4 22.5 14.6 14.5 16.7 6.5 5.7 1.9 8.0 8.9 4.4 2.8 9.2 11.0 0.0 2.3 11.6 7.0 1.9 4.8 13.6 11.5 22.7 32.4 9.1 15.3 1.3 10.1 12.6 17.2 10.7 13.7 9.5 23.6 34.6 46.6 9.4 0.0 26.1 6.4 8.2 37.2 14.4 11.9 14.3 15.3 10.6 45.9 33.9 3.1 7.2 29.1 27.8 7.8 7.2 15.4 13.2 15.8 4.7 7.7 6.8 3.1 0.0 19.3 19.2 67.9 53.1 5.9 13.5 6.7 12.7 11.5 5.2 14.6 ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626787-203744081 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 175.3" "Cell type enhanced" "Detected in many" "Adipocytes: 171.6;Oligodendrocyte precursor cells: 199.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ: 200.0;BJ hTERT+: 276.4;fHDF/TERT166: 212.8;SuSa: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB016118: AB_2061729, HPA040431: AB_2676980" "unprognostic (7.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.60e-2)" "unprognostic (8.17e-2)" "unprognostic (2.53e-2)" "unprognostic (9.23e-3)" "unprognostic (8.68e-2)" "unprognostic (3.81e-2)" "unprognostic (9.74e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (3.52e-3)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-3)" 58.9 25.0 39.7 25.6 36.3 16.0 16.6 0.0 33.5 47.5 0.3 58.2 12.5 104.5 20.1 32.5 48.4 25.2 59.5 40.2 13.3 9.9 9.3 35.1 12.8 8.0 8.0 40.6 9.9 11.8 3.8 40.6 11.2 33.0 30.2 42.5 7.1 69.7 14.4 54.8 14.4 175.3 0.2 12.2 15.4 27.4 44.7 21.7 15.1 27.7 19.4 37.2 15.3 2.6 45.7 7.8 15.6 15.1 120.4 175.1 84.5 200.0 276.4 32.1 27.4 3.8 22.8 9.8 28.8 212.8 43.5 43.5 22.6 27.7 34.3 126.5 8.0 28.7 37.4 2.5 43.1 42.0 51.3 130.5 26.9 102.9 16.2 81.6 63.5 57.1 12.9 20.3 25.1 2.5 44.3 14.5 9.7 8.7 24.2 22.3 11.6 16.7 11.3 4.0 4.6 6.7 68.3 10.5 30.2 222.1 9.3 21.4 54.9 80.5 11.4 136.6 48.3 13.4 20.9 5.4 80.7 31.0 24.5 3.2 2.0 0.0 8.7 1.3 6.4 0.9 5.4 7.2 2.2 0.3 1.3 3.4 4.0 3.8 2.2 3.7 5.7 2.7 39.7 36.3 0.0 33.5 40.2 13.3 8.0 8.0 11.2 0.2 44.7 2.6 171.6 89.8 68.2 127.6 9.9 97.1 18.9 43.1 41.5 4.8 11.2 9.4 76.5 7.2 35.0 18.4 2.1 27.9 56.2 2.2 0.0 35.3 5.8 78.0 92.4 67.6 23.9 35.9 55.9 14.9 18.9 56.0 13.7 89.7 10.1 30.6 58.9 18.2 38.5 117.8 9.8 2.4 14.2 14.7 38.8 4.8 43.8 20.4 26.6 37.5 18.1 136.1 66.9 199.0 40.4 31.4 11.1 38.0 27.6 48.2 7.2 3.3 39.7 7.8 19.7 50.7 81.2 21.7 2.8 54.7 150.9 26.0 59.7 8.0 3.3 62.0 ATP6V1D "ATP6M, VATD, VMA8" ENSG00000100554 "ATPase H+ transporting V1 subunit D" Q9Y5K8 14 67294371-67360265 "Metabolic proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 365.9;Proximal tubular cells: 365.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031515, HPA057316" Enhanced Approved Nucleoplasm Yes No 19000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA031515: AB_10600785, HPA057316: AB_2683409" "unprognostic (1.10e-1)" "unprognostic (7.35e-2)" "unprognostic (1.59e-1)" "unprognostic (7.10e-3)" "unprognostic (1.52e-1)" "unprognostic (7.64e-2)" "unprognostic (7.78e-3)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (3.05e-2)" "unprognostic (1.13e-2)" "unprognostic (3.08e-2)" "prognostic favorable (7.60e-13)" "unprognostic (2.78e-1)" "unprognostic (3.18e-2)" "unprognostic (1.41e-2)" "unprognostic (1.44e-2)" 43.4 116.2 98.0 32.2 103.2 28.8 43.8 91.8 119.7 40.3 101.8 52.9 40.4 34.3 72.5 96.7 48.1 38.7 136.6 107.2 103.5 129.8 51.7 37.5 33.3 96.1 98.4 26.1 36.2 88.8 65.8 43.4 106.7 55.7 57.5 78.0 45.1 49.8 78.5 40.4 41.7 46.4 95.1 24.3 43.8 42.5 99.7 52.4 89.5 108.5 46.3 54.5 54.1 99.6 242.5 64.7 96.2 62.4 80.2 82.8 73.5 199.1 109.4 145.8 109.1 76.2 85.2 24.8 73.9 155.1 105.3 89.2 72.6 117.9 195.7 82.5 50.8 23.4 74.5 51.0 144.0 24.9 64.8 65.1 77.7 105.4 73.1 131.4 97.6 58.6 50.2 55.3 206.6 78.5 66.5 46.2 60.7 104.6 83.3 48.8 84.2 32.8 171.2 104.3 120.2 49.8 122.9 65.4 145.6 96.2 98.3 53.4 123.8 162.4 121.6 77.6 120.1 55.8 46.1 33.4 150.2 44.1 96.1 106.7 77.5 92.8 48.5 78.8 40.8 39.9 53.2 52.7 83.4 42.0 41.6 41.7 94.0 48.9 83.5 73.9 78.8 65.0 98.0 103.2 91.8 119.7 107.2 103.5 96.1 98.4 106.7 95.1 99.7 99.6 31.3 54.5 63.0 13.4 27.6 96.2 66.6 112.3 26.2 60.0 44.8 41.8 160.8 55.8 85.0 82.8 54.2 92.3 51.4 91.6 365.9 125.9 190.3 120.8 44.1 40.7 54.4 78.1 22.7 48.9 85.5 51.5 42.3 71.8 41.2 39.8 27.5 45.8 132.0 87.5 21.0 49.4 175.0 44.6 61.0 97.9 32.9 62.2 80.0 6.5 58.5 89.4 47.4 9.5 22.1 121.5 78.7 50.8 21.3 65.9 80.9 365.5 184.1 94.2 13.1 44.5 64.1 100.1 61.5 78.4 138.4 205.9 40.8 71.6 40.6 113.8 ATP6V1G3 "ATP6G3, Vma10" ENSG00000151418 "ATPase H+ transporting V1 subunit G3" Q96LB4 1 198523222-198540945 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "kidney: 59.3" "Cell type enriched" "Detected in some" 48 "Distal tubular cells: 444.1" "Cancer enriched" "Detected in single" 140 "renal cancer: 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;BJ hTERT+: 1.1;fHDF/TERT166: 4.4;hTERT-RPE1: 1.8;U-2197: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA028701 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "HPA028701: AB_10611681" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 59.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.8 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.5 1.1 0.8 0.3 0.0 0.0 0.0 0.2 4.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 0.0 0.0 0.0 0.0 444.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 ATXN10 "E46L, FLJ37990, SCA10" ENSG00000130638 "Ataxin 10" Q9UBB4 22 45671798-45845307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049531 Approved Supported "Plasma membrane,Cytosol" NA NA 40000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA049531: AB_2680806" "unprognostic (5.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (3.01e-2)" "unprognostic (7.50e-2)" "unprognostic (1.19e-3)" "unprognostic (3.18e-1)" "unprognostic (2.15e-2)" "unprognostic (5.07e-2)" "unprognostic (8.38e-2)" "unprognostic (3.51e-1)" "unprognostic (1.23e-2)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (7.48e-2)" "unprognostic (6.98e-2)" 40.9 59.5 42.2 34.7 46.1 41.9 41.7 35.3 56.8 50.6 26.9 43.7 23.8 50.0 39.0 46.4 56.1 39.6 74.5 50.2 49.6 53.5 64.8 38.2 48.3 37.6 40.1 57.7 57.4 64.9 56.1 48.8 42.1 46.5 36.3 55.1 41.6 40.9 70.6 34.9 27.8 50.2 42.5 34.2 34.4 57.3 46.5 65.9 63.0 59.3 51.6 51.1 45.8 44.5 163.4 84.9 156.2 95.0 70.5 107.6 85.4 181.0 194.3 128.1 139.4 42.9 106.4 169.3 73.2 184.5 66.4 94.4 114.3 121.3 137.7 32.8 119.4 78.9 141.7 79.8 101.9 213.1 56.4 109.0 82.9 66.5 103.1 153.1 96.3 76.2 58.7 89.8 197.2 69.6 116.7 95.6 104.2 90.8 64.0 166.2 60.7 135.9 162.6 152.3 86.9 136.6 113.5 67.2 129.2 119.8 101.4 111.9 87.6 127.5 47.7 46.0 61.4 87.8 57.3 136.8 79.5 88.5 138.5 80.5 99.9 91.8 69.0 121.7 92.3 72.1 68.0 84.3 163.9 72.6 74.4 71.9 4.7 86.2 138.5 58.1 70.8 120.2 42.2 46.1 35.3 56.8 50.2 49.6 37.6 40.1 42.1 42.5 46.5 44.5 38.1 35.3 33.3 127.3 50.6 50.5 124.2 156.0 68.9 66.3 45.4 50.0 94.2 65.8 76.7 58.8 20.9 101.9 32.3 17.1 68.4 91.1 69.2 53.7 53.7 44.4 60.3 63.1 148.6 69.5 106.3 70.7 34.1 49.8 39.9 93.5 36.4 54.9 72.2 70.7 157.9 35.4 79.3 49.0 36.5 40.6 57.5 48.3 24.9 103.0 67.9 79.3 27.8 186.5 168.1 51.6 24.0 75.6 53.3 115.2 18.6 66.9 67.6 53.6 46.0 45.1 54.6 133.8 108.3 65.1 41.5 52.3 47.8 102.2 44.5 102.0 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 147.2;Kupffer cells: 187.5;Langerhans cells: 185.5;Prostatic glandular cells: 123.4;Sertoli cells: 210.4;Smooth muscle cells: 171.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.1;plasmacytoid DC: 25.7" "Group enriched" "Detected in many" 12 "dendritic cells: 25.7;NK-cells: 11.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 501.2;U-251 MG: 540.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 72000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 43.6 18.8 17.5 15.5 22.6 1.7 26.6 19.7 17.7 36.1 12.4 42.5 11.7 34.4 8.7 17.6 25.4 22.4 26.7 16.6 18.8 9.8 15.0 25.9 6.2 26.8 20.6 24.7 6.3 10.7 7.3 34.2 22.1 19.2 12.6 5.8 10.6 24.6 9.4 20.0 19.0 37.1 20.9 37.7 21.4 18.6 24.0 7.2 16.6 11.3 5.0 32.5 25.2 21.9 408.0 160.0 9.7 1.3 34.6 34.7 0.5 314.5 280.2 450.9 278.2 8.5 185.5 0.2 124.7 501.2 235.3 33.3 0.4 211.8 384.8 0.7 0.3 0.0 100.4 6.3 125.0 0.3 0.3 26.4 3.8 266.7 409.5 254.8 169.8 0.1 15.8 0.5 284.6 0.5 0.2 0.4 4.1 1.0 76.3 0.2 165.3 0.3 202.3 0.2 0.1 0.1 81.5 0.6 1.8 57.4 0.9 7.2 351.8 317.8 214.6 307.7 540.8 0.5 0.9 1.0 211.5 0.5 241.8 1.5 0.3 0.2 0.1 0.4 0.2 0.1 0.3 0.1 6.0 0.1 0.3 0.3 0.3 11.1 0.2 25.7 0.4 0.3 17.5 22.6 19.7 17.7 16.6 18.8 26.8 20.6 22.1 20.9 24.0 21.9 13.5 9.6 3.6 35.9 1.9 41.7 88.3 10.3 3.4 0.5 2.3 14.2 8.6 1.5 4.4 5.5 0.0 4.2 0.8 0.1 0.0 6.9 8.7 6.0 45.8 17.7 0.0 0.0 0.8 0.2 2.1 147.2 1.5 5.4 0.0 17.3 11.0 1.2 28.8 1.7 1.1 0.1 2.0 187.5 185.5 5.5 61.5 61.4 26.6 30.9 3.1 26.8 0.0 11.1 0.5 14.5 0.1 79.7 0.8 123.4 0.3 0.1 2.8 1.2 210.4 38.1 171.1 1.9 2.0 1.2 29.1 11.5 3.6 2.5 0.1 28.0 B3GNT9 MGC4655 ENSG00000237172 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9" Q6UX72 16 67148104-67150998 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 12.9;Leydig cells: 11.5;Peritubular cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SiHa: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052743, HPA062734" Approved Approved "Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoli fibrillar center" "HPA052743: AB_2681934, HPA062734: AB_2684854" "unprognostic (2.56e-2)" "unprognostic (2.22e-1)" "unprognostic (2.34e-2)" "unprognostic (1.07e-1)" "unprognostic (6.58e-2)" "unprognostic (1.11e-1)" "unprognostic (1.32e-3)" "unprognostic (3.28e-2)" "unprognostic (3.01e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "unprognostic (2.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.51e-2)" "unprognostic (1.15e-1)" "unprognostic (4.96e-3)" "unprognostic (7.56e-3)" 7.7 8.4 7.1 4.2 8.0 0.2 5.7 7.5 6.8 15.0 8.4 7.6 3.2 13.4 7.3 5.2 13.7 6.8 13.8 7.1 8.0 7.4 2.5 9.0 2.9 8.7 9.7 15.0 3.5 21.8 20.5 7.9 8.7 11.8 3.3 1.4 9.0 14.8 1.9 5.9 5.6 7.8 9.3 5.6 6.1 6.0 7.7 1.5 18.7 2.1 2.5 11.7 8.9 11.1 4.9 8.8 0.7 0.9 27.7 28.6 1.0 22.5 36.2 14.4 18.5 4.0 0.8 0.6 1.5 34.9 6.0 11.1 0.3 1.0 7.8 7.6 3.2 0.7 9.7 3.5 22.3 0.6 0.5 23.7 8.3 14.0 0.4 35.8 2.0 0.5 1.0 2.7 22.6 2.6 2.6 1.2 5.4 3.8 7.7 7.4 12.9 4.4 2.3 6.0 5.0 11.2 50.9 0.2 0.8 4.3 1.3 3.9 4.6 25.6 1.1 25.9 10.2 3.2 2.4 0.8 31.9 1.3 12.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 7.1 8.0 7.5 6.8 7.1 8.0 8.7 9.7 8.7 9.3 7.7 11.1 1.2 6.4 5.0 1.0 1.2 3.2 2.8 2.4 9.6 1.6 3.2 2.3 2.6 5.7 2.4 3.7 0.0 0.3 0.1 0.4 0.0 1.3 5.3 2.5 7.6 2.0 2.4 0.0 0.4 1.7 0.5 12.9 2.6 2.2 0.0 3.0 6.4 0.1 1.8 0.0 1.3 0.9 2.0 0.6 3.3 6.9 11.5 0.4 1.8 0.0 0.1 0.9 0.0 1.0 2.3 0.9 0.1 13.5 4.7 2.4 0.1 0.9 4.2 0.3 6.6 3.2 6.6 4.4 2.8 2.7 4.1 0.8 1.5 2.9 0.8 1.3 B4GALT4 beta4Gal-T4 ENSG00000121578 "Beta-1,4-galactosyltransferase 4" O60513 3 119211732-119240946 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 76.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 123.6;Urothelial cells: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 125.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046819, HPA063546" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA046819: AB_2679824, HPA063546: AB_2685036" "unprognostic (4.07e-2)" "unprognostic (1.78e-2)" "unprognostic (3.27e-2)" "unprognostic (1.14e-3)" "unprognostic (4.59e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (6.30e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-1)" "unprognostic (6.10e-3)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" 12.4 9.1 6.8 10.7 8.4 20.1 11.1 6.5 8.1 16.4 8.7 30.6 28.6 14.8 76.0 17.7 21.8 33.2 12.9 7.0 6.9 24.1 16.6 9.9 9.9 6.9 6.7 18.4 19.5 15.1 18.2 25.7 6.9 13.7 35.2 9.9 12.2 14.7 6.3 14.1 32.5 13.6 7.0 9.4 29.3 8.3 7.5 7.4 16.4 6.5 11.5 37.6 10.5 7.2 60.1 100.3 12.8 9.8 36.0 31.1 65.3 125.8 54.4 54.4 56.2 65.4 18.3 11.8 23.9 61.3 32.2 78.6 20.7 15.0 59.9 23.5 6.8 15.1 20.3 31.7 25.3 8.9 15.7 21.2 21.4 23.0 19.3 21.6 5.8 8.0 11.2 11.7 25.5 18.4 5.3 10.7 17.6 34.0 27.2 4.9 11.8 4.7 31.2 60.3 10.9 24.0 29.4 14.6 27.9 28.2 30.2 5.7 4.9 27.3 24.0 15.2 13.5 27.2 21.5 16.1 23.5 10.1 23.5 20.1 4.1 8.3 13.3 5.2 7.3 4.2 7.3 7.9 5.5 3.2 13.6 7.1 2.5 14.8 5.0 3.4 2.7 5.7 6.8 8.4 6.5 8.1 7.0 6.9 6.9 6.7 6.9 7.0 7.5 7.2 8.5 0.0 9.4 7.2 17.1 10.7 22.2 48.9 12.0 10.8 14.9 12.4 9.2 61.5 69.1 7.3 4.2 36.2 46.0 43.2 1.9 30.7 2.1 40.1 16.9 8.4 13.8 7.8 11.9 33.2 123.6 24.0 36.2 74.5 13.3 35.0 3.9 10.8 14.4 18.5 11.1 78.7 16.2 9.8 14.8 2.4 14.9 14.9 14.2 6.5 10.9 22.2 39.1 10.6 10.2 40.5 50.2 28.2 27.4 30.7 59.3 22.6 52.6 10.2 19.7 13.9 16.9 1.7 8.4 14.0 10.5 52.3 23.1 20.0 23.6 171.6 BAG2 ENSG00000112208 "BAG cochaperone 2" O95816 6 57172326-57189833 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 73.3;Early spermatids: 152.3;Spermatocytes: 93.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018862, HPA019918" Enhanced Supported "Intermediate filaments,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "Intermediate filaments" "HPA018862: AB_2669957, HPA019918: AB_2670317" "unprognostic (3.93e-1)" "unprognostic (1.62e-1)" "unprognostic (2.60e-1)" "unprognostic (1.33e-1)" "unprognostic (5.63e-2)" "unprognostic (8.32e-3)" "prognostic unfavorable (6.72e-6)" "unprognostic (1.10e-1)" "unprognostic (7.79e-5)" "unprognostic (6.20e-3)" "unprognostic (4.71e-2)" "unprognostic (6.56e-2)" "unprognostic (6.07e-3)" "unprognostic (5.97e-3)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.26e-4)" "unprognostic (6.24e-3)" 3.7 4.4 2.5 6.6 2.7 1.5 1.7 2.8 4.0 11.4 3.0 32.6 2.1 25.1 3.9 7.2 9.1 7.3 9.1 2.5 2.7 2.8 4.1 5.0 2.7 2.3 2.7 8.5 1.6 0.4 2.0 7.6 2.4 11.2 4.5 4.9 1.0 15.9 9.2 1.3 6.5 29.0 2.3 1.1 7.8 6.4 2.6 1.3 4.6 6.5 2.1 22.5 5.9 3.0 17.2 9.3 3.9 13.8 9.4 26.9 10.9 27.2 25.8 19.2 18.2 12.1 8.6 5.7 25.3 43.2 15.7 3.1 22.5 2.4 18.3 18.3 16.4 16.7 13.3 27.5 14.5 14.8 3.7 13.1 1.2 15.8 14.6 11.4 15.2 13.0 34.1 7.9 19.1 1.3 10.5 12.4 14.8 0.3 9.6 9.5 10.9 11.4 23.2 2.8 4.9 4.4 12.2 0.9 10.1 17.8 2.1 12.7 20.8 10.9 17.9 23.2 27.4 5.3 5.5 12.5 9.7 5.8 1.0 0.1 0.2 0.5 1.9 0.2 2.2 3.5 1.7 1.9 0.9 3.0 3.4 2.9 0.1 2.1 0.0 0.3 2.0 1.1 2.5 2.7 2.8 4.0 2.5 2.7 2.3 2.7 2.4 2.3 2.6 3.0 2.4 3.2 3.7 4.6 16.7 2.4 4.6 5.0 1.8 6.9 4.1 2.7 40.0 0.0 3.8 3.7 12.5 73.3 8.0 0.6 1.9 11.6 152.3 11.0 35.5 3.1 1.8 12.2 8.1 3.7 18.2 46.2 3.1 4.2 4.5 25.6 2.2 15.8 15.8 10.1 10.0 0.3 14.2 2.6 6.6 35.9 31.1 5.1 7.2 5.6 9.1 8.2 3.1 10.6 10.6 5.4 1.3 38.7 13.0 6.2 0.4 33.9 9.1 16.9 6.6 32.1 31.0 93.5 9.8 1.3 3.8 18.9 12.2 30.6 1.3 2.1 BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 38.5;Bipolar cells: 13.8;Cardiomyocytes: 9.1;Excitatory neurons: 22.3;Smooth muscle cells: 25.8;Theca cells: 9.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 36.6;BJ hTERT+ SV40 Large T+: 28.0;BJ hTERT+ SV40 Large T+ RasG12V: 20.9;HBF TERT88: 26.5;U-138 MG: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009564, HPA031440, HPA056104" Enhanced Supported "Nuclear speckles,Mitochondria" "Secreted to blood" NA Yes 16000000 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Mitochondria" "CAB009564: AB_2064213, HPA031440: AB_2673883, HPA056104: AB_2683038" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" 0.4 0.5 1.9 0.2 2.4 0.2 0.2 3.3 5.3 0.6 0.1 0.4 0.3 0.2 3.3 0.6 0.1 0.7 3.6 8.2 1.9 0.6 0.1 2.0 0.1 3.3 2.1 0.5 0.4 0.0 1.2 1.6 2.5 2.0 0.1 0.7 0.3 1.8 0.4 0.9 0.1 0.1 0.4 0.1 0.3 0.6 1.6 0.3 1.0 0.0 0.1 2.1 0.6 0.8 2.9 12.2 0.3 0.0 3.7 2.2 0.0 36.6 7.9 28.0 20.9 0.1 4.0 0.0 3.7 11.8 0.5 1.4 0.1 0.2 26.5 0.2 0.1 0.0 3.5 0.0 17.4 0.2 0.2 9.2 4.2 6.8 3.7 18.1 1.3 0.1 0.0 0.1 4.8 0.0 0.0 0.0 4.0 0.1 2.9 0.0 2.0 0.0 4.5 0.0 0.2 1.1 7.8 0.1 0.1 1.7 0.2 0.0 11.0 37.6 6.9 14.4 9.2 0.5 0.1 0.0 14.1 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.4 3.3 5.3 8.2 1.9 3.3 2.1 2.5 0.4 1.6 0.8 0.2 38.5 0.5 1.6 0.0 0.6 0.4 0.5 1.8 13.8 0.5 0.9 9.1 0.0 0.4 1.8 4.2 0.4 0.0 0.1 0.0 0.8 1.8 0.3 0.3 0.2 0.0 0.0 22.3 0.0 0.5 6.1 0.0 0.1 1.3 1.9 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.4 1.5 0.3 0.9 1.8 0.0 0.0 0.2 0.0 2.0 2.2 0.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 1.8 0.0 1.8 25.8 3.7 0.8 2.3 0.0 0.7 0.0 9.3 0.1 0.1 BECN1 "ATG6, VPS30" ENSG00000126581 "Beclin 1" Q14457 17 42810134-42833350 "Predicted intracellular proteins" "Antiviral defense, Apoptosis, Autophagy, Cell cycle, Cell division, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003949, CAB010143, HPA028949" Supported Supported "Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "Nuclear bodies" "CAB010143: AB_626746, HPA003949: , HPA028949: AB_2672839" "unprognostic (1.97e-1)" "unprognostic (2.66e-2)" "unprognostic (9.97e-2)" "unprognostic (3.80e-3)" "unprognostic (1.46e-1)" "unprognostic (2.01e-2)" "unprognostic (5.16e-3)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.59e-2)" "unprognostic (4.33e-2)" "unprognostic (1.81e-1)" "unprognostic (2.34e-1)" "unprognostic (1.02e-1)" "unprognostic (4.63e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-2)" 45.3 41.4 26.9 41.8 27.7 50.7 43.9 27.4 37.8 35.7 30.9 70.3 56.6 31.5 47.7 49.5 36.1 34.4 58.9 28.5 29.1 47.9 43.7 39.6 47.9 27.4 27.9 26.7 39.5 41.7 20.5 26.2 27.8 42.3 64.8 26.5 36.0 41.3 95.8 36.4 50.1 44.4 28.4 39.8 53.0 24.2 28.3 41.4 36.7 77.6 56.2 49.2 29.7 28.5 47.4 79.0 27.9 48.7 95.7 56.8 54.9 95.1 104.2 69.5 73.8 61.4 61.9 68.9 69.3 118.9 70.0 52.7 48.9 85.3 123.4 105.0 59.4 58.0 74.9 105.5 71.4 111.0 114.3 76.8 99.1 69.4 66.0 61.8 90.2 75.4 50.5 67.1 86.4 40.1 66.1 61.1 29.0 88.5 40.6 56.3 100.6 69.3 74.1 88.6 33.5 34.9 52.0 43.5 100.7 61.4 72.0 92.9 121.6 82.8 38.8 57.0 99.7 103.8 84.8 57.4 84.3 54.0 106.7 154.1 133.2 122.1 103.1 152.1 105.1 112.6 114.4 111.6 120.2 123.7 96.4 100.2 191.0 107.8 144.2 75.7 180.1 171.8 26.9 27.7 27.4 37.8 28.5 29.1 27.4 27.9 27.8 28.4 28.3 28.5 43.7 38.5 46.1 11.8 38.7 29.7 26.7 40.1 39.3 12.3 38.3 22.7 6.0 30.0 39.1 12.9 10.4 23.5 37.8 59.5 58.7 46.2 18.2 35.0 28.3 33.9 28.3 36.2 12.1 69.6 32.3 23.1 42.3 31.5 43.1 20.5 31.4 46.2 38.8 21.9 11.7 60.2 30.5 65.4 36.8 11.9 21.5 43.1 42.7 3.7 67.2 26.9 50.4 5.5 9.8 53.6 45.4 26.7 51.2 37.8 49.1 40.3 51.7 13.4 26.3 25.6 36.0 31.6 14.9 44.9 37.6 38.0 39.8 33.8 51.1 46.7 BEND6 "bA203B9.1, C6orf65, FLJ30162" ENSG00000151917 "BEN domain containing 6" Q5SZJ8 6 56955107-57027346 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 30.9;retina: 11.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.6;Excitatory neurons: 87.3;Horizontal cells: 42.1;Inhibitory neurons: 118.6;Oligodendrocyte precursor cells: 49.8" "Cancer enriched" "Detected in many" 6 "glioma: 4.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 8.8" "Lineage enriched" "Detected in many" 6 "dendritic cells: 8.8" "Cell line enhanced" "Detected in many" "ASC TERT1: 28.8;fHDF/TERT166: 28.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031605, HPA052973" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA031605: AB_10602395, HPA052973: AB_2682002" "unprognostic (4.27e-1)" "unprognostic (7.05e-2)" "unprognostic (4.42e-2)" "unprognostic (1.18e-6)" "unprognostic (2.44e-1)" "unprognostic (2.10e-1)" "unprognostic (1.17e-1)" "unprognostic (1.77e-2)" "unprognostic (9.41e-3)" "unprognostic (1.57e-1)" "unprognostic (8.82e-2)" "unprognostic (1.94e-2)" "unprognostic (9.84e-6)" "unprognostic (9.27e-3)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.98e-3)" 1.2 2.1 12.1 1.5 14.2 0.7 0.6 30.5 30.9 4.0 2.9 1.4 0.5 2.8 0.7 1.2 1.0 3.8 2.4 12.6 16.0 0.6 0.2 0.6 0.9 19.5 16.0 2.0 0.4 0.7 1.7 2.0 20.4 2.4 1.5 11.8 0.5 2.4 3.9 1.0 0.7 3.6 12.1 0.8 0.8 1.0 15.7 1.1 0.8 0.6 0.8 2.8 1.7 21.7 5.4 2.2 1.3 0.6 17.6 28.8 4.9 16.1 15.6 7.1 8.2 0.2 2.4 0.1 5.2 28.7 9.9 0.7 1.8 0.8 8.7 2.4 1.0 3.6 7.5 0.4 4.7 10.3 0.2 12.7 4.5 9.8 4.3 11.9 4.7 13.3 4.6 9.2 14.3 5.5 6.2 2.5 4.4 0.3 1.3 0.1 0.2 2.6 2.6 5.4 6.1 6.2 10.8 1.3 1.4 6.1 0.3 5.9 6.1 21.5 0.7 14.5 3.6 12.6 15.2 4.3 12.6 6.5 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 8.8 0.0 0.1 12.1 14.2 30.5 30.9 12.6 16.0 19.5 16.0 20.4 12.1 15.7 21.7 0.4 0.0 0.0 16.6 0.3 0.9 0.2 0.2 0.0 82.6 0.2 1.1 3.6 0.0 0.7 0.0 4.2 0.5 10.8 0.0 0.0 0.2 0.6 0.5 11.9 0.2 0.0 0.0 87.3 0.4 1.6 5.6 0.0 0.5 0.0 13.5 1.1 0.0 0.1 42.1 118.6 0.0 0.0 0.0 4.0 0.8 1.8 1.1 3.6 13.1 0.3 4.9 0.0 49.8 22.9 0.6 0.0 3.0 0.0 0.4 0.0 1.0 0.0 4.8 0.0 8.7 2.7 0.7 5.8 0.2 1.0 0.0 0.1 4.4 0.0 0.1 BGN "DSPG1, SLRR1A" ENSG00000182492 Biglycan P21810 X 153494980-153509546 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 795.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 223.5;Peritubular cells: 782.7;Sertoli cells: 1485.7;Smooth muscle cells: 401.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 312.6;BJ hTERT+: 400.8;fHDF/TERT166: 568.9;HSkMC: 283.9;hTEC/SVTERT24-B: 235.2;HUVEC TERT2: 561.2;U-138 MG: 249.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003157, CAB003678" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 3300000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Endoplasmic reticulum" "CAB003678: AB_425325, HPA003157: AB_1078282" "unprognostic (1.74e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-3)" "unprognostic (3.60e-1)" "unprognostic (5.42e-2)" "unprognostic (3.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.22e-2)" "unprognostic (1.76e-3)" "unprognostic (1.30e-2)" "unprognostic (2.63e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (6.00e-8)" "unprognostic (7.05e-3)" "unprognostic (2.40e-2)" "unprognostic (5.66e-2)" "unprognostic (2.57e-3)" 165.8 213.0 54.1 93.1 57.6 0.3 118.0 51.2 91.5 371.0 69.5 69.3 22.0 234.4 83.7 45.8 143.7 326.1 795.8 56.1 48.7 396.5 347.9 477.3 42.4 50.6 50.8 94.9 67.9 26.6 144.1 199.1 53.2 184.2 24.8 1.1 107.7 135.5 32.4 118.9 48.8 213.2 45.5 352.1 51.6 69.9 64.6 15.9 250.0 46.7 35.9 126.8 180.0 65.4 0.0 0.0 29.7 0.1 31.5 70.5 1.1 312.6 400.8 56.7 18.6 39.5 0.0 0.0 56.9 568.9 2.0 0.1 0.0 0.0 10.2 0.0 0.0 0.0 0.6 3.9 27.0 0.0 0.2 283.9 2.2 235.2 10.7 29.0 561.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.0 1.5 0.3 0.2 0.0 0.1 0.0 0.6 0.4 0.0 0.0 1.1 11.8 1.3 0.0 120.0 249.5 2.3 1.0 1.5 0.9 0.1 0.0 0.1 0.3 114.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 57.6 51.2 91.5 56.1 48.7 50.6 50.8 53.2 45.5 64.6 65.4 30.5 3.2 5.6 5.9 0.6 104.1 1.3 7.3 5.7 0.2 1.2 5.6 16.1 4.3 2.5 9.2 0.0 15.5 0.7 0.0 1.9 2.7 1.8 1.4 28.3 45.2 0.0 5.3 0.1 0.2 50.0 180.0 7.7 1.1 3.8 8.4 223.5 1.6 4.4 3.3 0.1 0.0 0.0 4.0 43.6 13.5 147.9 3.0 35.6 25.3 2.0 0.1 0.0 20.6 0.0 1.2 0.0 782.7 0.0 3.0 0.0 0.8 1.6 0.2 1485.7 3.1 401.3 0.8 1.2 1.8 54.1 56.9 3.0 7.7 0.0 1.6 BIRC2 "API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48" ENSG00000110330 "Baculoviral IAP repeat containing 2" Q13490 11 102347211-102378670 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005513, CAB020661" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli fibrillar center, Cytosol" Nucleoplasm "CAB020661: , HPA005513: AB_1846746" "unprognostic (1.36e-1)" "unprognostic (3.29e-1)" "unprognostic (9.52e-3)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (7.02e-2)" "unprognostic (2.72e-2)" "unprognostic (1.04e-2)" "unprognostic (1.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.05e-2)" "unprognostic (3.02e-2)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (9.20e-2)" "unprognostic (5.00e-2)" "unprognostic (1.64e-2)" 23.2 27.6 18.4 25.8 19.6 36.4 28.2 20.0 23.4 27.5 22.5 27.2 23.6 25.7 30.2 18.1 19.7 24.8 23.6 17.9 19.9 28.8 44.3 22.6 34.5 19.7 19.4 21.8 33.7 20.4 18.8 29.4 19.8 21.4 26.0 22.2 21.1 16.1 29.7 18.2 25.2 21.6 20.1 26.7 23.5 24.6 18.8 50.6 22.2 32.9 27.1 30.4 20.4 24.9 34.0 24.7 37.3 29.3 46.1 63.3 23.9 128.3 48.8 71.9 43.4 30.9 81.7 37.1 123.5 59.2 40.3 36.7 24.5 33.8 85.7 50.0 12.6 37.2 17.6 37.8 46.9 22.9 23.0 40.8 64.4 41.2 52.3 66.2 50.1 22.2 34.4 0.2 131.0 10.9 24.3 20.1 18.1 40.1 23.7 11.9 48.4 24.9 55.4 38.5 15.5 20.3 44.7 26.9 40.7 56.7 42.5 27.3 82.7 150.7 34.4 46.2 84.2 14.9 21.9 25.0 32.6 28.2 112.5 97.2 43.3 104.4 22.9 42.2 18.9 15.7 21.5 21.3 33.8 15.1 27.4 27.7 67.6 34.3 46.7 20.4 33.2 27.5 18.4 19.6 20.0 23.4 17.9 19.9 19.7 19.4 19.8 20.1 18.8 24.9 61.8 41.7 41.1 17.0 52.6 67.2 109.2 53.6 39.9 24.4 52.3 52.8 58.6 67.2 49.5 64.4 29.2 38.4 77.9 85.7 43.0 49.8 20.8 63.2 54.0 51.0 48.5 80.0 22.4 73.7 27.8 55.9 28.5 85.7 62.7 43.7 59.3 182.1 41.5 20.2 21.7 54.3 46.8 84.3 71.5 11.2 36.4 71.1 51.6 26.2 81.2 34.3 55.6 21.6 33.1 54.5 71.1 29.0 49.2 75.0 82.1 110.1 56.6 31.0 26.3 45.7 48.9 44.7 42.4 28.4 62.8 35.2 57.1 36.4 44.2 82.5 BMP1 "BMP-1, PCOLC" ENSG00000168487 "Bone morphogenetic protein 1" P13497 8 22165140-22212326 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor, Hydrolase, Metalloprotease, Protease" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 69.3;Endometrial stromal cells: 52.8;Smooth muscle cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014572 Enhanced "Secreted to extracellular matrix" NA NA 9200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA014572: AB_1845390" "unprognostic (1.24e-1)" "unprognostic (8.01e-2)" "unprognostic (3.75e-2)" "unprognostic (5.89e-2)" "unprognostic (1.34e-2)" "unprognostic (6.76e-2)" "unprognostic (9.53e-2)" "unprognostic (2.64e-3)" "unprognostic (1.66e-1)" "unprognostic (9.75e-3)" "unprognostic (7.05e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.37e-9)" "unprognostic (2.11e-2)" "unprognostic (6.57e-2)" "unprognostic (1.50e-3)" "unprognostic (3.34e-2)" 11.7 17.4 3.8 6.3 4.6 1.4 9.0 4.7 4.4 15.6 4.9 8.1 4.8 12.7 3.9 7.0 11.8 9.8 5.9 4.3 3.9 7.7 14.7 8.3 1.7 5.0 4.1 5.9 4.4 3.4 3.4 27.3 4.1 9.6 5.3 0.6 3.7 6.1 3.4 6.2 5.9 14.4 4.3 5.0 4.3 2.4 4.2 1.5 10.0 3.1 1.8 10.4 10.3 4.4 15.2 20.4 7.4 30.2 47.8 41.8 23.2 54.1 50.1 33.8 27.6 5.1 27.4 3.7 32.0 56.9 18.9 51.2 5.1 27.8 6.5 3.6 6.9 6.7 24.5 7.9 31.7 2.9 14.3 49.8 26.5 25.2 11.4 78.3 31.4 5.2 7.1 10.6 19.6 4.6 1.4 3.0 4.7 17.0 8.3 6.4 8.2 15.2 26.7 4.1 2.8 10.6 52.5 3.1 13.4 20.4 5.0 8.3 41.4 17.0 18.4 32.3 23.9 4.0 2.2 0.6 23.8 10.1 28.0 0.0 0.4 0.0 0.6 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.2 0.0 0.1 3.8 4.6 4.7 4.4 4.3 3.9 5.0 4.1 4.1 4.3 4.2 4.4 12.5 6.4 69.3 5.5 0.8 6.2 5.2 22.6 4.0 2.6 5.0 6.1 4.9 2.8 6.7 5.5 0.0 3.3 3.2 31.9 0.0 25.1 0.7 3.1 52.8 14.1 3.0 0.8 3.5 8.2 9.5 28.7 1.1 5.7 15.2 13.9 14.6 20.1 4.3 1.7 2.7 6.2 0.0 3.4 6.1 1.1 10.2 5.4 10.6 4.7 1.0 2.2 3.1 6.6 6.7 15.3 18.6 10.9 2.8 4.7 13.2 4.1 2.2 1.1 26.3 6.4 43.7 1.5 4.0 6.5 5.3 24.4 3.3 34.2 10.7 8.0 BMPER "CRIM3, Cv2" ENSG00000164619 "BMP binding endothelial regulator" Q8N8U9 7 33904308-34156427 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Excitatory neurons: 286.9;Hepatic stellate cells: 117.8;Inhibitory neurons: 90.1;Oligodendrocyte precursor cells: 105.1" "Cancer enhanced" "Detected in some" "glioma: 2.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 14.5;fHDF/TERT166: 17.0;HBF TERT88: 17.2;HSkMC: 15.5;hTEC/SVTERT24-B: 14.9;U-138 MG: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.50e-2)" "unprognostic (2.68e-1)" "unprognostic (2.83e-2)" "unprognostic (3.19e-2)" "unprognostic (1.93e-1)" "unprognostic (1.96e-4)" "unprognostic (5.34e-3)" "unprognostic (3.10e-1)" "unprognostic (9.98e-3)" "unprognostic (3.50e-3)" "unprognostic (8.01e-4)" "unprognostic (1.96e-1)" "unprognostic (5.67e-5)" "unprognostic (2.54e-1)" "unprognostic (2.62e-1)" "unprognostic (2.06e-2)" "unprognostic (3.47e-3)" 3.1 0.5 0.7 3.9 0.9 0.0 1.8 1.4 1.5 3.8 0.0 1.2 0.6 1.6 2.2 0.6 1.3 0.8 1.5 0.9 0.3 0.2 5.1 5.1 0.5 0.6 0.4 2.1 0.1 0.1 1.7 5.5 0.9 3.5 0.8 0.3 0.8 0.2 1.8 0.2 2.3 1.0 0.5 0.2 4.0 0.4 0.3 0.3 0.4 3.7 0.0 1.5 1.4 0.8 0.0 0.6 0.0 0.0 14.5 7.9 0.0 10.8 4.1 8.1 6.9 0.0 0.0 0.0 0.0 17.0 4.1 6.3 0.0 0.0 17.2 0.0 0.4 0.0 0.0 0.0 1.6 0.0 0.0 15.5 0.0 14.9 0.1 0.8 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 2.1 0.8 0.0 0.0 22.5 1.1 9.2 0.0 0.7 0.0 0.0 8.4 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 1.4 1.5 0.9 0.3 0.6 0.4 0.9 0.5 0.3 0.8 1.1 0.0 0.0 29.0 0.2 0.0 0.6 0.3 0.0 0.4 0.2 0.0 4.6 0.0 0.0 0.0 6.2 0.5 0.0 0.0 0.0 0.1 1.9 0.2 3.2 1.3 4.2 2.7 286.9 0.0 0.5 14.3 0.0 0.4 0.0 1.5 117.8 0.3 0.1 0.0 90.1 0.1 0.0 2.8 0.0 1.0 0.0 0.3 0.0 18.7 0.0 0.2 0.0 105.1 9.8 0.0 0.0 1.2 0.0 1.1 0.0 0.0 0.0 0.5 0.0 5.0 2.1 1.3 5.8 0.1 0.1 0.1 0.2 0.3 0.1 0.3 BPNT2 "FLJ20421, gPAPP, IMPA3, IMPAD1" ENSG00000104331 "3'(2'), 5'-bisphosphate nucleotidase 2" Q9NX62 8 56957931-56993867 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 22.6;Cardiomyocytes: 53.8;Cytotrophoblasts: 18.0;dendritic cells: 16.2;Extravillous trophoblasts: 91.8;Hofbauer cells: 26.6;Syncytiotrophoblasts: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 480000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: AB_1079138" "unprognostic (1.62e-2)" "unprognostic (7.89e-3)" "unprognostic (6.58e-2)" "unprognostic (6.42e-2)" "unprognostic (2.00e-1)" "unprognostic (8.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (4.24e-3)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (1.68e-3)" "unprognostic (2.89e-1)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" 37.6 37.3 14.8 16.1 19.9 12.4 19.3 19.2 19.8 25.5 8.9 17.4 13.3 21.9 16.2 19.1 13.4 16.5 29.4 16.0 17.9 23.4 36.2 17.2 12.3 17.2 17.6 11.8 19.6 35.6 13.7 24.9 17.7 31.0 17.6 19.7 21.9 23.6 37.4 14.3 12.7 25.7 15.3 15.5 16.9 16.5 18.0 15.4 27.1 30.1 13.3 22.4 12.2 29.3 42.4 34.5 26.0 26.9 78.2 53.3 35.7 62.9 60.9 44.1 38.3 17.4 29.2 26.3 47.0 67.3 31.2 33.7 31.8 42.5 65.0 36.4 22.7 51.4 23.0 31.2 48.5 33.0 35.1 43.2 41.6 39.7 63.9 40.8 59.5 24.3 22.5 46.1 48.9 22.1 40.6 19.8 19.2 48.1 12.7 27.9 23.4 29.7 46.0 24.9 10.1 28.1 35.3 42.9 36.3 27.1 38.4 23.9 50.1 59.3 34.2 59.2 45.8 47.5 42.5 27.8 81.0 27.0 37.3 1.8 0.9 0.5 0.9 0.6 0.7 0.7 0.6 0.5 0.7 0.9 0.6 1.1 2.5 3.2 2.6 1.0 0.4 0.3 14.8 19.9 19.2 19.8 16.0 17.9 17.2 17.6 17.7 15.3 18.0 29.3 22.6 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.8 0.0 0.0 0.0 0.0 18.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 91.8 14.4 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 33.8 1.8 0.0 0.0 0.0 BZW1 "BZAP45, KIAA0005" ENSG00000082153 "Basic leucine zipper and W2 domains 1" Q7L1Q6 2 200810594-200827338 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 3845.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047288, HPA053272" Uncertain Approved Vesicles NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA047288: , HPA053272: " "unprognostic (2.45e-2)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.08e-3)" "unprognostic (1.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.31e-3)" "unprognostic (3.98e-3)" "prognostic unfavorable (5.10e-4)" "unprognostic (4.49e-3)" "unprognostic (7.93e-3)" "unprognostic (1.08e-3)" "unprognostic (8.97e-3)" "unprognostic (4.38e-2)" "unprognostic (3.04e-1)" "unprognostic (7.61e-2)" "unprognostic (8.03e-2)" "unprognostic (1.24e-1)" 130.6 129.1 30.3 97.5 33.0 219.6 88.7 37.7 40.9 65.5 49.2 98.4 64.6 66.6 58.4 120.8 53.4 93.1 56.4 33.9 36.9 88.5 227.0 73.5 97.9 36.5 36.7 62.3 62.6 72.4 30.7 105.2 35.3 99.6 90.6 45.8 61.2 61.7 101.7 47.9 71.4 80.1 39.1 62.8 69.0 170.9 42.1 123.0 74.4 75.2 109.4 164.6 61.4 45.4 296.6 230.1 309.4 187.1 305.2 353.3 221.6 425.2 501.8 281.2 244.5 360.7 195.3 142.5 144.7 339.7 186.1 159.8 284.9 512.6 521.8 154.6 151.3 370.8 453.9 280.1 244.5 420.9 199.6 205.3 233.5 373.2 398.9 244.6 495.4 132.3 328.5 234.0 379.3 236.6 387.9 201.3 392.4 120.1 575.4 293.1 333.4 148.6 256.1 435.2 188.9 218.7 325.5 120.9 226.1 255.5 126.6 216.7 555.0 416.8 242.9 255.2 276.6 286.1 428.6 377.8 341.2 209.3 312.1 236.7 140.7 168.5 177.9 173.4 207.2 102.0 126.0 167.5 162.6 87.1 112.4 156.7 117.0 218.5 195.1 75.5 171.5 294.6 30.3 33.0 37.7 40.9 33.9 36.9 36.5 36.7 35.3 39.1 42.1 45.4 207.3 86.6 108.1 31.3 148.5 198.5 318.5 310.7 125.7 37.1 159.0 89.8 18.1 82.9 290.3 90.1 18.8 115.4 263.2 127.5 138.9 250.2 927.0 108.3 145.3 149.0 96.7 72.8 28.7 233.1 164.3 181.2 72.4 150.0 196.9 72.7 99.2 262.4 114.1 58.9 32.1 113.3 183.1 88.6 194.0 3845.6 102.2 169.1 124.5 15.0 308.1 119.6 170.0 24.6 36.6 464.4 106.5 95.9 132.7 242.3 68.2 163.3 121.7 33.4 98.6 159.4 179.8 175.2 169.2 133.2 196.1 195.2 200.3 103.3 106.1 370.9 C10orf105 FLJ00245 ENSG00000214688 "Chromosome 10 open reading frame 105" Q8TEF2 10 71711701-71737824 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 34.6" "Group enriched" "Detected in some" 4 "Early spermatids: 8.7;Langerhans cells: 2.4;Late spermatids: 5.1;Melanocytes: 3.6" "Cancer enriched" "Detected in single" 9 "glioma: 0.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.8;non-classical monocyte: 2.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 5 "BJ hTERT+: 3.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (2.60e-3)" "unprognostic (6.76e-3)" "unprognostic (5.45e-1)" "unprognostic (4.14e-1)" "unprognostic (1.17e-1)" "unprognostic (1.37e-6)" "unprognostic (5.25e-2)" "unprognostic (2.10e-3)" "unprognostic (1.47e-1)" "unprognostic (8.08e-2)" "unprognostic (3.87e-2)" "unprognostic (1.35e-1)" "unprognostic (7.37e-2)" "unprognostic (4.64e-1)" "unprognostic (1.53e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" 0.6 0.0 14.4 0.7 15.0 0.5 0.1 13.8 7.7 0.2 4.2 0.1 0.2 0.1 0.0 0.1 0.4 0.2 0.2 9.2 19.4 0.0 0.1 0.5 1.1 27.3 34.6 0.5 0.0 0.0 0.1 0.1 19.2 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.2 0.0 17.3 2.8 0.1 1.4 22.5 0.5 0.0 0.1 0.4 0.1 0.2 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 2.1 0.0 0.0 0.1 14.4 15.0 13.8 7.7 9.2 19.4 27.3 34.6 19.2 17.3 22.5 13.6 0.4 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.4 5.1 0.0 0.7 3.6 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 C11orf87 "LOC399947, LOH11CR1A, NEURIM1" ENSG00000185742 "Chromosome 11 open reading frame 87" Q6NUJ2 11 109422190-109429167 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 15.3" "Group enriched" "Detected in some" 6 "Excitatory neurons: 52.4;Horizontal cells: 20.2;Inhibitory neurons: 33.3" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Region enhanced" "Detected in many" "cerebral cortex: 15.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 2.9;fHDF/TERT166: 11.7;SCLC-21H: 2.9" "Low region specificity" "Detected in all" HPA034656 Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA034656: AB_10600788" "unprognostic (5.42e-2)" "unprognostic (2.09e-1)" "unprognostic (2.28e-1)" "unprognostic (8.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.85e-1)" "unprognostic (1.63e-1)" "unprognostic (1.55e-2)" "unprognostic (1.62e-1)" "unprognostic (2.44e-2)" "unprognostic (2.45e-1)" "unprognostic (5.28e-5)" "unprognostic (8.38e-2)" "unprognostic (9.65e-2)" "unprognostic (2.72e-6)" 0.0 0.1 2.2 0.0 3.2 0.0 0.0 0.0 15.3 0.9 0.0 0.0 0.0 0.9 0.3 0.0 0.2 0.0 0.0 6.5 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.9 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.4 0.0 0.1 0.1 2.9 1.4 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.2 0.0 15.3 6.5 0.1 0.0 1.1 0.0 1.5 9.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 52.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 20.2 33.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 4.5 5.1 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C12orf75 "AGD3, OCC-1, OCC1" ENSG00000235162 "Chromosome 12 open reading frame 75" Q8TAD7 12 105235290-105396097 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 109.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 841.2;Ductal cells: 626.3;Endometrial ciliated cells: 579.1;Extravillous trophoblasts: 1228.2;Proximal tubular cells: 762.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 661.2" "Group enriched" "Detected in all" 6 "dendritic cells: 661.2;T-cells: 169.9" "Cell line enhanced" "Detected in all" "BJ: 877.8;BJ hTERT+: 517.0;fHDF/TERT166: 432.7;RPTEC TERT1: 425.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065311 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA065311: AB_2685463" "unprognostic (5.96e-2)" "unprognostic (3.85e-1)" "unprognostic (9.86e-2)" "unprognostic (1.02e-1)" "unprognostic (6.73e-2)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (8.61e-2)" "unprognostic (1.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.33e-1)" "unprognostic (7.00e-2)" "prognostic favorable (1.69e-5)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.00e-1)" "unprognostic (4.47e-3)" 12.2 7.3 4.3 8.9 4.7 11.3 11.6 9.4 7.2 31.3 2.1 24.9 9.2 18.5 6.1 8.7 20.9 38.2 2.5 4.1 8.8 58.5 2.0 7.5 14.7 5.3 5.5 6.6 33.8 20.1 3.5 9.3 4.9 41.2 22.0 2.8 4.2 109.3 32.0 9.5 8.8 6.7 6.5 6.3 49.9 26.6 8.8 10.8 2.9 11.8 19.1 5.0 27.0 5.4 43.6 66.6 16.5 14.9 61.2 117.3 30.3 877.8 517.0 194.2 109.4 133.2 3.6 12.2 348.9 432.7 31.7 70.4 36.6 50.3 212.9 241.1 65.0 38.8 17.7 26.5 7.7 29.8 37.7 49.6 12.0 66.4 73.8 113.0 26.1 69.9 1.9 58.8 192.4 14.4 115.3 262.5 39.6 15.8 153.3 21.6 44.3 11.2 425.3 4.3 73.5 18.4 36.9 7.7 16.2 45.2 22.6 7.1 44.2 201.7 77.2 77.0 118.1 34.9 57.6 58.8 44.5 9.7 55.3 39.0 0.7 1.2 165.5 0.5 80.4 19.7 69.2 169.9 23.3 16.2 19.8 102.4 3.5 69.4 1.6 661.2 144.1 88.3 4.3 4.7 9.4 7.2 4.1 8.8 5.3 5.5 4.9 6.5 8.8 5.4 12.8 3.2 2.8 1.6 61.2 100.2 65.9 21.9 38.7 4.5 32.2 26.9 1.1 271.7 20.9 187.6 4.2 35.3 519.5 469.8 841.2 626.3 152.3 579.1 32.6 14.8 333.2 15.8 2.7 222.3 1228.2 53.0 160.5 293.1 2.5 9.7 13.2 1.8 31.9 63.9 2.9 63.6 85.5 5.3 97.3 324.1 15.5 48.2 60.5 40.3 29.1 6.4 299.7 0.5 0.4 420.0 175.5 4.9 160.3 87.0 102.1 762.3 129.7 4.9 6.6 8.6 127.8 102.9 118.6 37.1 61.2 40.6 143.0 0.7 63.9 37.3 CALD1 "CDM, H-CAD, L-CAD" ENSG00000122786 "Caldesmon 1" Q05682 7 134744252-134970729 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 916.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1190.3;Leydig cells: 1745.0;Peritubular cells: 2005.6;Sertoli cells: 2294.3;Smooth muscle cells: 2549.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 736.3;fHDF/TERT166: 1202.8;U-138 MG: 733.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000006, HPA008066, HPA017330" Enhanced Enhanced "Plasma membrane,Actin filaments" Yes No 39000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments" "CAB000006: AB_2065456, HPA008066: AB_1078378, HPA017330: AB_1845917" "unprognostic (2.16e-2)" "unprognostic (1.19e-2)" "unprognostic (2.80e-3)" "unprognostic (3.05e-2)" "unprognostic (4.51e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.22e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (6.52e-3)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" 225.8 119.2 27.3 164.9 35.0 1.3 161.1 28.1 47.6 241.6 37.2 916.1 80.3 523.3 150.7 275.6 304.4 203.2 115.0 26.9 29.1 134.7 224.4 155.5 75.4 32.3 30.4 326.2 52.5 32.7 53.3 430.0 30.9 348.9 149.8 13.1 70.3 781.7 46.5 76.0 233.1 688.4 27.9 129.2 324.2 52.7 33.4 28.5 114.1 75.2 34.4 505.3 208.0 28.8 115.9 75.3 163.3 146.1 572.7 464.8 161.6 661.6 736.3 227.2 246.6 138.3 3.5 0.7 153.3 1202.8 148.1 26.9 106.0 202.3 308.4 1.5 38.9 4.0 87.8 94.7 375.6 1.5 0.8 360.9 153.6 252.8 147.4 343.6 193.0 0.0 0.6 1.6 338.7 0.3 0.6 3.2 197.7 0.1 25.6 1.4 146.6 2.3 46.9 32.2 29.0 72.1 235.3 31.7 90.0 491.0 7.2 1.4 508.5 733.2 130.0 143.8 230.3 0.9 1.1 1.3 259.0 0.8 573.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.9 0.2 0.0 0.0 0.0 2.9 27.3 35.0 28.1 47.6 26.9 29.1 32.3 30.4 30.9 27.9 33.4 28.8 400.6 22.4 17.6 43.1 7.3 420.4 379.6 218.8 164.4 172.0 115.5 466.1 456.5 228.8 33.5 44.1 6.2 202.7 5.0 0.3 23.5 392.6 61.0 89.4 1190.3 432.9 3.6 16.0 95.4 23.6 903.9 886.9 16.3 206.2 5.1 251.0 422.0 638.4 43.5 92.5 58.3 1.2 28.5 21.0 112.8 83.6 1745.0 38.8 336.2 94.6 8.4 140.6 6.2 98.5 158.8 146.0 0.2 2005.6 4.2 456.9 0.1 332.1 11.3 21.2 2294.3 326.1 2549.3 12.1 12.2 70.1 171.8 276.6 27.5 414.1 0.8 36.7 CALM2 "CAMII, PHKD" ENSG00000143933 "Calmodulin 2" P0DP24 2 47160083-47176921 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007790, HPA044999" Approved NA Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB007790: AB_562257, HPA044999: AB_2679177" "prognostic unfavorable (5.05e-4)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.84e-4)" "unprognostic (9.21e-2)" "unprognostic (2.04e-3)" "prognostic unfavorable (8.35e-5)" "unprognostic (1.63e-2)" "unprognostic (4.67e-3)" "unprognostic (1.79e-2)" "unprognostic (1.97e-2)" "unprognostic (1.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.18e-2)" "unprognostic (2.29e-2)" "prognostic favorable (1.94e-5)" "unprognostic (1.24e-1)" 509.3 652.1 1177.9 334.4 1219.1 240.3 686.1 1229.7 1745.6 420.1 988.8 683.9 549.8 507.6 551.1 366.8 526.5 390.8 443.0 1229.0 1219.0 445.7 493.1 505.6 427.9 1209.1 1192.8 416.1 213.3 332.3 441.3 468.9 1227.6 449.1 706.0 574.8 490.8 561.5 262.9 304.2 621.2 634.7 1209.4 643.0 390.4 508.8 1257.9 571.0 443.3 258.1 467.2 459.0 340.2 1411.8 2459.6 905.8 1062.2 459.7 579.4 679.5 655.8 2177.2 1504.3 1437.1 1240.1 958.1 923.2 956.1 979.5 1753.2 1030.4 624.7 878.3 855.6 1907.0 729.3 438.6 821.6 526.6 1409.6 779.5 996.3 686.2 381.2 825.0 1265.3 1347.0 1230.4 977.3 312.8 812.1 854.7 3485.7 635.9 1270.2 984.3 801.3 2961.6 488.6 314.3 1142.9 1021.9 1631.0 441.0 756.8 2016.6 726.5 756.0 1120.1 1144.3 573.7 556.7 1084.8 1060.8 1135.8 627.0 1703.6 648.8 529.1 1038.2 718.8 711.3 1357.7 944.7 447.6 776.8 139.7 844.1 177.2 285.6 203.4 213.2 354.0 182.1 173.7 201.6 417.9 277.1 761.4 445.6 227.4 496.5 1177.9 1219.1 1229.7 1745.6 1229.0 1219.0 1209.1 1192.8 1227.6 1209.4 1257.9 1411.8 597.4 1387.8 613.5 195.2 570.7 1780.5 1101.0 2616.3 524.8 654.3 844.4 572.9 639.6 581.9 1751.8 759.6 98.0 931.4 649.8 906.5 2304.8 1977.0 312.7 889.1 363.8 652.0 597.1 697.1 317.5 683.4 627.9 943.6 354.8 452.5 665.4 484.5 280.6 536.6 1267.1 341.6 179.0 1020.1 3352.8 867.1 1858.2 287.0 1055.3 911.0 1771.6 143.4 1167.2 2063.1 350.1 129.7 339.8 2584.9 1114.4 863.6 309.7 1016.8 1231.6 1020.2 3245.3 334.2 907.2 671.6 1882.0 2193.5 714.3 503.0 1663.1 255.3 669.1 615.4 771.1 1062.2 CALU ENSG00000128595 Calumenin O43852 7 128739292-128773400 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 504.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 2467.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006018 Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 21000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA006018: AB_1845934" "unprognostic (7.22e-3)" "unprognostic (1.16e-3)" "unprognostic (3.16e-1)" "unprognostic (8.86e-2)" "unprognostic (1.27e-1)" "unprognostic (9.52e-3)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.05e-3)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (2.75e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.30e-11)" "unprognostic (3.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.60e-5)" 115.8 56.6 20.6 137.9 22.7 22.8 66.2 22.8 28.5 133.5 54.7 97.5 37.6 113.6 61.1 60.4 57.1 92.7 236.9 24.5 23.5 45.1 74.2 68.5 38.8 24.1 22.2 54.8 52.6 85.0 28.8 211.8 24.2 113.0 81.3 19.6 67.7 150.1 82.1 29.9 40.0 328.4 22.3 47.5 62.5 39.8 33.2 31.0 77.1 117.1 45.2 160.1 48.2 26.6 257.8 207.4 486.6 152.7 1348.5 1229.5 270.9 1821.7 1378.1 577.5 770.7 238.6 388.3 100.0 351.5 2467.8 850.4 144.9 258.2 318.2 826.5 80.6 138.2 136.6 283.7 295.0 657.1 187.2 254.3 930.5 223.6 868.3 370.6 904.4 537.3 116.4 237.9 172.8 1131.8 141.0 130.2 95.5 305.2 247.0 197.3 122.9 333.3 164.5 243.5 132.7 44.3 238.2 595.4 481.5 753.1 932.2 106.2 145.6 799.8 1706.6 234.2 1350.8 754.6 306.8 385.7 224.8 1478.6 223.6 1857.2 21.7 38.8 23.5 28.3 41.4 27.9 23.7 19.5 22.0 33.4 16.6 17.1 20.0 4.5 26.2 35.7 32.9 23.4 31.2 20.6 22.7 22.8 28.5 24.5 23.5 24.1 22.2 24.2 22.3 33.2 26.6 67.3 22.4 38.5 25.5 29.9 81.3 68.1 82.0 31.3 28.2 51.7 42.7 247.0 25.8 62.7 25.8 18.8 116.8 25.0 14.4 17.6 69.5 11.4 37.5 186.3 104.0 19.7 42.3 37.7 60.5 504.7 198.8 37.2 72.8 59.6 62.6 113.2 54.2 136.9 28.6 47.0 55.9 22.4 58.9 70.7 9.3 100.3 44.6 120.9 27.2 26.3 32.4 21.6 31.2 32.2 71.5 11.4 118.8 140.9 110.6 12.6 17.7 57.2 12.8 59.2 64.9 162.8 27.1 41.9 30.9 76.9 243.0 30.9 69.7 26.1 90.5 CAP2 ENSG00000112186 "Cyclase associated actin cytoskeleton regulatory protein 2" P40123 6 17393505-17557790 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 577.1;tongue: 313.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.5;Excitatory neurons: 158.1;Inhibitory neurons: 137.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 26.1;basal ganglia: 40.9;cerebral cortex: 87.2;hippocampal formation: 50.2;white matter: 32.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 101.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050530, HPA054147" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA050530: AB_2681159, HPA054147: AB_2682400" "unprognostic (7.27e-2)" "unprognostic (5.71e-3)" "unprognostic (1.63e-2)" "unprognostic (1.55e-1)" "unprognostic (4.86e-1)" "unprognostic (2.23e-2)" "unprognostic (9.94e-2)" "unprognostic (3.58e-2)" "unprognostic (7.72e-2)" "unprognostic (1.65e-1)" "unprognostic (6.43e-2)" "unprognostic (2.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (1.47e-1)" "unprognostic (8.05e-2)" "unprognostic (1.75e-3)" 17.8 11.6 26.1 7.6 40.9 0.0 10.7 0.9 87.2 15.4 2.9 32.6 4.1 28.5 17.8 21.7 16.8 11.4 113.6 50.2 11.1 8.7 4.5 4.7 1.7 3.2 3.8 4.5 4.2 7.5 5.1 8.8 2.7 25.1 9.6 9.1 7.7 30.7 577.1 2.6 8.9 42.7 0.0 3.1 9.8 1.5 9.1 3.1 5.5 313.0 2.3 14.5 6.4 32.3 15.5 24.6 44.4 55.1 0.3 0.1 10.4 52.3 42.7 46.6 43.0 8.1 6.9 0.0 48.9 62.1 60.5 8.2 21.3 20.9 66.8 0.1 7.9 0.0 15.4 26.5 4.3 0.0 0.0 3.5 9.9 23.1 10.3 72.3 2.2 0.0 0.0 0.1 101.6 25.2 0.0 0.0 17.0 0.8 15.6 5.2 59.1 1.1 23.6 6.4 6.1 10.9 19.0 59.2 31.3 82.8 65.0 11.2 0.2 36.6 31.6 1.0 47.6 0.0 0.0 0.2 11.7 0.1 48.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 40.9 0.9 87.2 50.2 11.1 3.2 3.8 2.7 0.0 9.1 32.3 2.0 3.2 1.5 9.8 0.0 1.9 4.3 6.2 5.7 16.4 10.2 8.4 126.5 4.3 5.4 1.8 4.2 16.5 0.0 1.9 3.9 2.7 0.1 13.9 13.7 2.7 6.0 0.0 158.1 0.7 12.2 7.9 0.0 5.8 0.0 22.8 3.9 2.4 2.2 8.4 137.2 1.3 2.0 0.0 2.2 0.0 0.6 0.3 0.0 10.3 0.0 6.3 0.0 16.6 7.2 3.7 1.9 4.9 0.0 1.9 0.0 16.7 33.9 2.2 32.9 25.5 43.4 0.1 3.2 2.1 0.9 37.5 0.3 0.3 1.6 0.6 CAV1 CAV ENSG00000105974 "Caveolin 1" Q03135 7 116524994-116561179 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Cancer-related genes, Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2160.5;Alveolar cells type 1: 3557.7;Basal keratinocytes: 1375.3;Endothelial cells: 1024.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 14.6;memory B-cell: 5.1" "Group enriched" "Detected in many" 57 "B-cells: 5.1;granulocytes: 14.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 2140.5;BJ hTERT+: 2371.6;HBEC3-KT: 2333.7;LHCN-M2: 2372.1;U-138 MG: 1894.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 122.1" "CAB003791, HPA049326" Enhanced Supported "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB003791: AB_562068, HPA049326: AB_2680714" "unprognostic (5.98e-2)" "unprognostic (1.35e-3)" "unprognostic (3.35e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-3)" "unprognostic (2.35e-3)" "unprognostic (8.07e-2)" "prognostic unfavorable (7.17e-5)" "unprognostic (1.31e-1)" "unprognostic (2.25e-1)" "unprognostic (1.79e-3)" "unprognostic (7.92e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.65e-3)" "unprognostic (2.72e-1)" "unprognostic (7.40e-2)" "unprognostic (6.14e-3)" 621.1 17.4 12.7 44.7 15.3 0.6 284.5 14.3 21.6 267.0 11.8 298.8 32.3 190.9 72.5 135.1 152.5 148.2 276.5 12.2 13.9 18.4 26.6 592.0 30.3 15.1 13.4 137.4 24.6 21.4 6.8 449.2 14.6 110.3 93.6 31.4 58.0 175.5 102.9 104.9 89.4 274.2 14.3 199.1 120.8 25.8 16.1 25.2 168.4 184.6 20.3 202.0 124.1 16.2 458.7 344.3 9.5 3.7 1406.6 2140.5 20.6 1055.8 2371.6 566.0 591.2 3.0 652.4 0.1 365.8 1228.5 494.8 828.2 2.2 2333.7 840.3 36.0 19.5 0.4 128.7 0.3 196.9 0.1 2.1 736.9 481.6 805.7 536.0 539.0 1749.9 0.2 0.3 23.4 2372.1 45.2 0.5 0.8 33.7 1.2 173.9 5.2 25.2 251.0 317.0 2.0 1.0 0.6 328.3 20.1 52.3 137.8 1.6 3.9 1349.3 1894.8 212.4 730.6 298.9 96.8 15.8 1.9 758.4 0.9 701.0 14.6 0.0 0.0 0.0 0.0 0.0 5.1 0.1 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 12.7 15.3 14.3 21.6 12.2 13.9 15.1 13.4 14.6 14.3 16.1 16.2 2160.5 3557.7 123.0 0.0 15.8 1375.3 392.0 534.8 316.4 8.3 17.9 190.8 286.6 107.2 342.0 7.3 2.1 64.3 7.0 0.3 5.9 76.8 2.6 17.5 102.3 1024.0 1.8 16.0 0.4 0.7 449.5 326.8 1.5 21.3 13.9 6.3 450.5 5.2 15.0 0.0 0.5 7.0 20.3 11.0 187.1 13.4 377.2 10.7 439.4 19.7 3.7 249.0 0.0 1.0 1.3 43.1 0.1 565.4 56.2 512.7 0.7 0.3 30.6 7.7 558.8 152.4 751.4 2.1 5.7 39.4 610.9 117.0 16.7 59.7 2.4 93.3 CAVIN1 "cavin-1, CGL4, PTRF" ENSG00000177469 "Caveolae associated protein 1" Q6NZI2 17 42402449-42423256 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Transcription termination" "RNA-binding, rRNA-binding" "Congenital generalized lipodystrophy, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 575.1;Alveolar cells type 1: 429.5;Breast myoepithelial cells: 154.9;Cytotrophoblasts: 159.8;Endothelial cells: 217.4;Smooth muscle cells: 211.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 1105.9;fHDF/TERT166: 796.6;TIME: 920.9;U-138 MG: 912.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049838, HPA074213" Supported Supported "Vesicles,Plasma membrane" NA NA 440000 "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Vesicles "HPA049838: AB_2680907, HPA074213: AB_2686674" "unprognostic (1.59e-1)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.36e-4)" "unprognostic (1.56e-1)" "unprognostic (1.76e-3)" "unprognostic (6.33e-3)" "unprognostic (1.72e-1)" "unprognostic (1.04e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (7.18e-3)" "unprognostic (2.36e-1)" "unprognostic (3.44e-3)" "unprognostic (4.24e-3)" "unprognostic (3.21e-2)" "unprognostic (2.07e-3)" "prognostic unfavorable (5.87e-4)" 397.8 65.3 42.6 69.1 47.2 3.7 295.3 55.8 40.9 239.9 50.6 314.0 30.8 344.3 56.8 101.0 207.5 78.1 220.9 35.4 49.7 66.4 21.0 202.8 30.0 68.8 55.0 162.5 28.4 26.5 34.8 151.3 60.1 181.5 50.7 3.6 84.2 215.4 144.8 161.9 104.1 242.3 53.5 109.0 132.8 22.6 47.2 16.6 112.4 92.7 24.0 255.4 192.3 58.0 315.9 264.8 5.5 69.8 342.3 409.6 6.9 1105.9 477.8 432.2 340.5 134.6 20.1 0.5 216.3 796.6 177.4 509.7 46.8 331.6 351.0 1.1 9.5 137.5 154.8 66.1 215.8 0.3 1.2 283.0 120.5 340.8 115.8 230.2 592.3 0.4 95.5 1.3 187.9 5.0 7.4 1.6 25.8 48.1 1.8 0.6 173.3 0.6 186.1 1.6 0.4 2.0 371.9 6.4 91.7 145.2 29.8 2.0 920.9 912.0 429.5 330.9 407.9 0.8 0.9 1.6 270.7 0.5 104.8 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 42.6 47.2 55.8 40.9 35.4 49.7 68.8 55.0 60.1 53.5 47.2 58.0 575.1 429.5 117.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 55.4 154.9 0.0 0.0 50.8 23.9 0.0 159.8 3.4 0.0 3.9 45.6 0.0 11.7 130.4 217.4 0.0 0.0 0.0 4.4 11.3 114.2 0.0 16.9 63.1 116.3 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.5 0.0 0.0 0.5 0.0 0.0 1.1 3.6 0.0 0.0 0.0 211.7 0.0 0.0 0.0 0.0 77.2 4.5 6.6 0.0 0.0 CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.1;Rod photoreceptor cells: 38.2;Theca cells: 78.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "BJ: 101.2;BJ hTERT+: 103.2;BJ hTERT+ SV40 Large T+ RasG12V: 96.4;HBF TERT88: 113.3;hTERT-HME1: 153.2;LHCN-M2: 176.9;TIME: 93.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Supported "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" 4.1 10.2 2.7 1.2 3.4 0.5 1.8 2.2 3.0 10.5 0.7 16.7 1.1 6.9 0.5 2.8 8.3 1.3 2.1 6.5 1.1 3.3 5.7 9.9 1.3 0.2 1.9 33.5 1.1 2.9 0.4 0.5 0.3 2.4 2.8 1.1 0.6 4.0 15.3 3.0 2.5 3.2 0.2 0.5 1.6 0.6 3.7 1.2 0.9 0.9 0.7 0.8 1.3 1.5 20.6 1.9 0.0 0.2 15.1 47.2 30.7 101.2 103.2 73.5 96.4 0.3 0.3 0.4 0.2 40.6 16.7 2.3 0.2 65.5 113.3 0.4 0.3 0.2 0.4 0.3 35.1 0.3 0.2 32.0 2.9 57.0 153.2 31.2 3.6 0.3 0.2 0.5 176.9 0.6 0.1 0.2 0.3 0.0 0.6 0.1 0.2 0.2 3.9 2.0 0.4 0.7 0.3 0.2 0.9 7.2 0.3 0.5 93.3 0.2 10.0 15.3 0.3 0.3 0.3 0.2 5.0 0.3 2.4 9.2 0.2 0.5 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.5 0.4 0.1 0.2 0.1 0.1 2.7 3.4 2.2 3.0 6.5 1.1 0.2 1.9 0.3 0.2 3.7 1.5 1.5 3.2 1.3 3.9 0.2 4.6 2.0 1.0 2.2 6.4 0.8 0.4 1.6 2.8 1.9 0.0 8.4 1.0 0.2 0.2 0.0 0.2 0.8 8.8 5.1 2.2 0.0 0.0 56.1 0.2 1.3 14.5 0.0 0.6 1.3 6.8 9.7 0.2 0.4 15.2 15.1 0.0 0.0 1.0 8.9 1.1 9.6 0.5 7.2 1.0 0.2 2.4 0.0 0.5 0.7 0.3 0.0 0.4 0.1 1.5 0.1 0.1 0.9 38.2 0.0 1.6 5.9 0.4 0.9 0.2 4.3 0.8 1.2 78.0 0.1 0.9 CCDC102B "ACY1L, AN, C18orf14, FLJ23594, HsT1731" ENSG00000150636 "Coiled-coil domain containing 102B" Q68D86 18 68715209-69055189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 28.4" "Cell type enhanced" "Detected in many" "Astrocytes: 72.8;Early spermatids: 138.2;Excitatory neurons: 80.8;Late spermatids: 83.3;Oligodendrocytes: 90.1;Sertoli cells: 78.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 9.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 9.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 14.2;BJ hTERT+: 29.0;fHDF/TERT166: 26.2;HSkMC: 15.4;Karpas-707: 10.2" "HPA040623, HPA048194" Approved Approved Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Cytosol "HPA040623: AB_10805715, HPA048194: AB_2680309" "unprognostic (3.92e-2)" "unprognostic (1.62e-1)" "unprognostic (5.58e-2)" "unprognostic (9.50e-3)" "unprognostic (7.13e-2)" "unprognostic (3.50e-1)" "unprognostic (7.87e-3)" "unprognostic (1.36e-1)" "unprognostic (5.59e-2)" "unprognostic (8.62e-3)" "unprognostic (1.95e-1)" "unprognostic (6.04e-2)" "prognostic unfavorable (2.90e-6)" "unprognostic (2.21e-2)" "unprognostic (2.12e-2)" "unprognostic (8.00e-3)" "unprognostic (3.13e-3)" 7.1 2.9 1.5 3.7 1.8 0.7 2.7 0.6 3.5 2.8 0.0 3.8 1.5 1.7 1.1 3.4 1.8 13.6 3.2 1.3 2.0 4.3 1.7 14.3 8.6 2.6 1.6 0.9 1.5 2.6 0.9 28.4 3.1 1.2 4.5 2.2 1.3 1.3 0.6 1.0 2.6 3.7 2.0 2.2 3.6 2.0 2.3 1.5 5.2 1.1 2.0 10.6 1.5 3.6 0.0 0.0 4.0 0.3 3.6 14.2 0.2 0.8 29.0 0.3 0.5 0.1 0.4 0.1 0.6 26.2 0.5 0.4 0.1 0.2 0.4 1.2 0.4 0.8 0.0 1.3 7.0 0.1 0.4 15.4 0.6 0.4 3.5 0.6 0.2 2.0 0.0 10.2 2.4 0.0 0.6 0.3 0.8 0.2 0.5 1.3 0.2 0.5 0.1 0.0 1.7 1.5 0.1 0.0 0.1 1.6 0.3 1.3 4.0 0.6 0.2 0.2 0.3 4.4 0.3 0.8 2.1 1.7 2.5 0.0 0.1 0.3 1.0 0.2 0.9 0.5 0.6 0.8 0.2 0.6 1.8 1.1 0.0 1.0 0.2 9.1 0.3 0.3 1.5 1.8 0.6 3.5 1.3 2.0 2.6 1.6 3.1 2.0 2.3 3.6 11.5 0.0 2.2 72.8 4.4 0.6 0.8 0.8 0.6 6.4 2.7 2.9 10.0 0.0 2.1 3.7 6.2 0.8 12.4 0.4 5.9 0.7 138.2 2.9 6.7 6.8 0.0 3.0 80.8 1.8 0.6 15.3 0.0 1.1 2.5 5.7 8.6 0.8 3.2 6.7 33.6 0.2 0.0 1.9 1.8 83.3 32.3 3.3 0.0 44.0 2.1 11.9 7.2 36.2 90.1 0.2 2.6 9.1 2.2 0.4 0.3 5.3 1.5 13.4 78.9 3.8 37.3 1.9 5.7 0.7 0.6 0.3 3.8 3.7 0.4 0.6 CCDC14 "DKFZp434L1050, FLJ12892" ENSG00000175455 "Coiled-coil domain containing 14" Q49A88 3 123897305-123961408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035278, HPA035279" Uncertain Enhanced "Centriolar satellite" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite" "HPA035278: AB_2674548, HPA035279: AB_10601253" "unprognostic (7.41e-3)" "unprognostic (5.18e-2)" "unprognostic (1.86e-1)" "unprognostic (1.41e-1)" "unprognostic (9.45e-2)" "prognostic favorable (5.27e-4)" "prognostic unfavorable (4.82e-4)" "unprognostic (6.83e-2)" "unprognostic (5.50e-2)" "unprognostic (2.12e-1)" "unprognostic (3.76e-1)" "prognostic unfavorable (4.76e-4)" "prognostic unfavorable (3.50e-8)" "unprognostic (2.14e-2)" "unprognostic (2.86e-1)" "unprognostic (9.37e-2)" "prognostic favorable (2.72e-5)" 11.8 9.6 5.3 12.8 8.5 36.6 21.4 6.4 7.5 17.1 4.6 22.5 12.8 22.1 35.5 10.0 14.5 13.6 8.6 5.1 8.7 14.4 15.3 13.7 16.6 8.8 7.5 17.4 16.8 5.6 13.7 10.6 9.0 16.3 34.8 43.2 14.9 7.9 6.2 23.8 15.4 14.2 7.7 12.4 13.9 23.7 10.1 20.5 13.2 2.9 15.0 12.0 12.4 10.0 42.6 22.5 72.1 28.0 10.6 16.1 34.0 79.9 26.2 41.6 45.2 17.5 28.5 12.4 19.9 19.1 30.1 44.5 27.1 14.8 55.9 10.5 20.0 49.9 50.7 17.7 9.0 31.2 29.9 15.1 9.7 20.7 21.9 49.0 19.7 48.9 25.8 21.0 28.1 18.3 26.4 17.3 22.2 19.0 28.0 47.2 29.0 15.2 23.3 34.1 25.4 28.3 45.2 13.0 33.4 46.5 27.5 31.2 22.9 91.1 45.8 28.5 26.5 20.0 15.8 32.8 32.2 25.6 31.5 1.1 0.6 1.3 1.4 0.9 1.0 0.8 1.2 1.2 0.3 0.7 1.3 1.1 0.1 2.5 0.2 1.8 2.6 0.7 5.3 8.5 6.4 7.5 5.1 8.7 8.8 7.5 9.0 7.7 10.1 10.0 22.1 22.4 71.5 72.8 21.3 21.9 36.4 31.2 25.6 35.9 48.9 37.7 14.6 38.6 29.4 36.8 60.5 27.5 27.6 67.9 0.0 26.1 38.6 33.7 44.0 23.8 89.7 72.1 83.8 13.8 22.9 32.3 26.0 29.9 25.9 67.9 28.5 22.3 20.9 28.6 67.7 85.6 67.1 19.7 29.9 17.3 32.6 21.0 24.9 41.2 20.1 18.6 49.4 91.0 77.1 22.8 63.7 31.2 25.3 20.4 41.6 12.6 18.9 75.5 19.7 39.2 29.4 144.0 49.6 18.2 16.1 11.6 30.3 33.5 77.7 22.9 CCDC50 "C3orf6, DFNA44, Ymer" ENSG00000152492 "Coiled-coil domain containing 50" Q8IVM0 3 191329085-191398659 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 363.7;Oligodendrocyte precursor cells: 365.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 630.7" "Lineage enriched" "Detected in all" 5 "dendritic cells: 630.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001336 Approved Supported Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA001336: AB_1078421" "unprognostic (5.01e-2)" "unprognostic (1.44e-1)" "unprognostic (7.84e-2)" "unprognostic (8.77e-3)" "unprognostic (1.73e-2)" "unprognostic (8.29e-2)" "prognostic unfavorable (2.48e-5)" "unprognostic (3.03e-2)" "unprognostic (2.51e-2)" "unprognostic (4.48e-2)" "unprognostic (3.17e-3)" "unprognostic (2.05e-2)" "unprognostic (7.79e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-2)" "unprognostic (7.57e-2)" "unprognostic (4.19e-1)" 63.2 28.3 19.6 34.3 20.7 10.3 30.6 21.5 19.1 24.1 18.8 26.9 24.2 33.0 24.8 27.9 24.3 34.8 39.7 17.6 23.3 32.4 56.5 31.6 42.2 24.1 22.0 46.2 35.1 27.6 13.5 34.9 24.1 26.2 25.4 11.8 23.7 33.3 19.0 18.4 25.8 48.1 23.2 45.0 24.3 29.6 21.3 17.7 27.4 26.1 41.0 36.7 18.6 24.7 74.9 24.5 93.6 24.7 82.3 72.1 32.3 135.4 135.2 95.4 95.0 52.6 28.9 14.6 163.0 76.8 70.6 83.6 75.6 60.5 141.9 109.0 37.8 10.0 31.7 60.3 120.8 36.8 37.8 58.2 79.3 75.6 169.7 82.2 148.7 0.0 33.9 77.3 85.4 26.0 0.2 23.1 33.2 7.6 103.0 56.3 51.9 73.1 104.3 31.9 21.8 33.2 48.2 51.6 95.8 67.3 35.6 32.9 153.3 93.4 78.4 68.4 176.3 118.6 54.9 0.9 50.5 0.1 76.9 0.1 22.1 2.1 5.9 20.8 2.4 128.5 6.1 3.9 44.3 76.5 1.3 1.5 2.2 24.0 12.1 630.7 22.1 18.0 19.6 20.7 21.5 19.1 17.6 23.3 24.1 22.0 24.1 23.2 21.3 24.7 143.5 25.6 54.5 40.5 134.5 46.9 52.5 30.7 30.7 27.2 32.5 37.5 48.4 58.6 34.7 51.5 27.1 28.1 363.7 44.1 31.3 120.4 183.0 97.3 58.1 134.0 22.8 11.2 15.8 78.5 36.3 66.6 41.8 79.0 2.5 58.5 175.6 79.5 84.4 25.2 41.3 33.8 38.7 59.4 78.3 92.1 69.3 61.4 53.4 98.4 101.4 32.1 5.2 365.4 28.9 174.7 33.9 75.6 102.7 69.8 37.6 71.8 26.3 14.4 59.2 74.1 65.7 73.2 26.6 24.0 32.5 33.5 22.4 49.5 33.7 62.4 CCDC81 "FLJ16339, FLJ23514" ENSG00000149201 "Coiled-coil domain containing 81" Q6ZN84 11 86374736-86423109 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 10.2;fallopian tube: 27.4" "Cell type enhanced" "Detected in many" "Early spermatids: 37.5;Endometrial ciliated cells: 72.7;Extravillous trophoblasts: 35.8;Respiratory ciliated cells: 38.4" "Cancer enhanced" "Detected in single" "testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 3.4;BJ hTERT+: 1.8;HBF TERT88: 1.9;SuSa: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.02e-1)" "unprognostic (6.06e-2)" "unprognostic (1.19e-2)" "unprognostic (2.30e-1)" "unprognostic (1.53e-1)" "unprognostic (6.76e-2)" "unprognostic (7.00e-3)" "unprognostic (8.54e-3)" "unprognostic (1.46e-3)" "unprognostic (2.82e-1)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (8.14e-4)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" "unprognostic (2.27e-1)" "unprognostic (6.62e-2)" 0.7 0.3 1.5 0.2 1.4 0.2 0.4 1.8 1.4 1.9 10.2 0.5 0.0 1.6 0.5 0.2 27.4 0.4 0.4 1.8 2.3 0.4 0.3 1.4 0.4 4.0 5.5 0.8 0.2 0.1 1.8 0.6 3.9 0.7 0.2 1.0 0.2 0.7 0.8 0.4 0.3 1.1 3.5 0.4 0.4 5.8 2.0 0.8 0.7 0.1 0.3 0.6 0.5 2.4 0.0 0.1 1.1 0.0 0.3 0.1 0.4 3.4 1.8 0.5 0.4 0.4 0.3 0.2 1.3 0.6 0.1 0.2 0.6 0.1 1.9 0.2 0.2 0.3 0.1 0.3 0.1 0.2 0.3 0.0 0.6 0.9 0.3 0.6 0.6 0.2 0.2 0.0 0.4 0.5 0.4 1.0 0.1 0.5 0.0 0.2 0.1 0.3 0.2 0.0 0.1 0.2 0.1 0.2 0.0 2.1 0.2 0.4 0.1 0.8 0.4 0.8 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.4 1.8 1.4 1.8 2.3 4.0 5.5 3.9 3.5 2.0 2.4 0.1 3.2 0.5 4.6 0.0 0.3 0.2 1.0 0.0 1.8 0.7 0.6 1.1 0.0 5.2 0.0 0.0 4.0 0.2 0.1 0.0 0.1 37.5 72.7 1.0 0.4 0.0 0.0 2.3 0.0 35.8 1.0 0.0 1.3 0.0 0.3 1.8 0.0 2.1 0.0 3.8 0.0 2.0 0.6 0.7 5.1 1.5 0.5 0.0 1.0 0.6 0.4 0.0 2.5 3.5 0.0 0.1 0.7 0.0 0.6 0.1 0.1 38.4 1.0 13.1 0.7 0.9 5.8 0.3 0.0 0.6 2.7 0.2 1.0 0.1 0.2 CCDC85A KIAA1912 ENSG00000055813 "Coiled-coil domain containing 85A" Q96PX6 2 56183990-56386172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3" "Cell type enhanced" "Detected in some" "Adipocytes: 57.7;Excitatory neurons: 228.7;Inhibitory neurons: 160.5;Microglial cells: 60.0" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 45.9;fHDF/TERT166: 74.5;U-266/70: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043106, HPA057020" Uncertain "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043106: AB_10794770, HPA057020: AB_2683311" "unprognostic (2.29e-1)" "unprognostic (1.28e-1)" "unprognostic (6.87e-2)" "unprognostic (3.66e-2)" "unprognostic (7.87e-2)" "unprognostic (7.62e-2)" "unprognostic (3.07e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (1.53e-2)" "unprognostic (2.57e-1)" "unprognostic (6.55e-5)" "unprognostic (3.28e-2)" "unprognostic (1.00e-1)" "unprognostic (2.88e-2)" "unprognostic (1.83e-2)" 12.5 0.6 5.4 0.6 7.4 0.0 3.5 1.2 8.0 2.5 0.0 0.7 0.3 6.3 0.8 0.7 2.1 1.2 4.5 6.9 7.2 1.0 0.1 5.5 0.5 17.3 6.5 0.5 0.7 1.3 0.2 10.0 7.0 2.0 0.7 4.0 1.2 2.7 5.4 1.7 0.4 4.7 11.8 0.7 0.5 0.4 5.1 0.6 9.1 7.5 0.6 0.7 0.7 15.2 0.0 0.8 0.1 0.0 13.9 0.8 0.0 11.6 1.1 9.8 0.9 0.0 0.1 45.9 1.7 74.5 0.0 2.0 0.0 0.0 5.6 0.0 0.3 0.0 0.6 0.0 0.7 0.0 0.1 3.3 0.3 0.0 1.2 5.5 9.7 0.0 0.0 6.1 1.3 0.2 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 1.7 1.3 0.0 0.3 0.1 0.0 2.1 5.3 0.0 15.3 7.9 2.3 0.1 0.9 32.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 7.4 1.2 8.0 6.9 7.2 17.3 6.5 7.0 11.8 5.1 15.2 57.7 25.6 0.6 15.3 0.8 3.3 0.5 0.0 0.0 7.8 0.6 0.5 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 0.3 3.6 0.2 1.9 14.8 1.2 0.0 228.7 0.4 0.1 3.7 0.0 0.5 0.0 0.2 8.6 0.0 2.3 0.0 160.5 0.2 0.0 0.3 2.0 11.9 0.3 0.3 5.4 60.0 0.0 0.7 0.0 33.7 7.2 0.7 0.1 0.0 0.1 0.3 0.0 0.3 0.0 1.5 0.0 10.0 2.7 0.2 0.8 0.1 1.3 0.1 0.1 3.6 0.9 0.3 CCIN "BTBD20, KBTBD14" ENSG00000185972 Calicin Q13939 9 36169388-36171334 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "testis: 74.7" "Group enriched" "Detected in some" 87 "Early spermatids: 913.7;Late spermatids: 247.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.5;BJ: 3.9;fHDF/TERT166: 4.7;hTEC/SVTERT24-B: 5.8;TIME: 7.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (5.10e-2)" "unprognostic (9.26e-3)" "unprognostic (6.27e-2)" "unprognostic (8.26e-6)" "unprognostic (1.78e-2)" "unprognostic (5.38e-2)" "unprognostic (1.57e-2)" "unprognostic (7.74e-3)" "unprognostic (5.43e-3)" "unprognostic (4.49e-2)" "unprognostic (1.77e-1)" "unprognostic (1.36e-1)" "unprognostic (5.98e-5)" "unprognostic (3.27e-3)" "unprognostic (7.86e-2)" "unprognostic (1.07e-1)" "unprognostic (2.43e-3)" 0.4 0.4 0.5 0.3 0.5 1.4 0.2 0.2 0.7 0.6 0.0 0.2 0.0 1.2 0.1 0.1 0.2 0.5 0.1 0.6 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.1 1.9 0.1 0.0 0.1 74.7 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.1 1.0 2.5 3.9 0.4 0.1 0.1 0.0 0.0 0.0 1.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 1.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 7.9 0.0 1.2 0.2 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.2 0.7 0.6 0.0 0.1 0.0 0.1 0.1 0.2 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 913.7 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.8 247.8 3.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.7 0.4 4.5 3.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 CCL11 "eotaxin, MGC22554, SCYA11" ENSG00000172156 "C-C motif chemokine ligand 11" P51671 17 34285742-34288334 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.7;lymphoid tissue: 31.4;stomach 1: 35.1;urinary bladder: 41.0" "Cell type enriched" "Detected in some" 15 "Fibroblasts: 38.9" "Cancer enhanced" "Detected in many" "stomach cancer: 12.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "BJ hTERT+: 9.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 88500 "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.61e-2)" "unprognostic (1.45e-1)" "prognostic favorable (8.70e-4)" "unprognostic (8.18e-2)" "prognostic favorable (1.99e-4)" "unprognostic (9.91e-2)" "unprognostic (8.09e-2)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (1.45e-1)" "unprognostic (9.64e-8)" "unprognostic (2.66e-2)" "unprognostic (1.05e-3)" "unprognostic (1.61e-1)" "unprognostic (2.72e-2)" 3.8 0.8 0.0 31.4 0.0 0.0 0.2 0.0 0.0 3.6 0.0 41.7 33.2 1.7 0.0 12.4 0.7 4.8 16.7 0.0 0.0 5.8 0.6 9.1 0.0 0.0 0.0 0.3 2.8 1.7 1.0 0.0 0.0 2.6 14.7 0.0 0.1 0.9 0.0 0.0 35.8 20.5 0.0 2.8 35.1 0.0 0.0 0.3 0.0 0.0 0.7 41.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 9.7 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.1 1.9 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.0 0.1 CCL7 "FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7" ENSG00000108688 "C-C motif chemokine ligand 7" P80098 17 34270221-34272242 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "bone marrow: 25.9" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 56.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 6 "thalamus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.5;BJ hTERT+ SV40 Large T+: 2.3;BJ hTERT+ SV40 Large T+ RasG12V: 2.8;HSkMC: 3.3" "Not detected" "Not detected" "Secreted to blood" NA NA 29700 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (7.66e-2)" "unprognostic (1.05e-2)" "unprognostic (8.53e-2)" "unprognostic (4.65e-2)" "unprognostic (2.54e-2)" "unprognostic (9.54e-2)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (2.63e-2)" "unprognostic (2.27e-3)" "unprognostic (7.04e-2)" "unprognostic (1.99e-8)" "unprognostic (2.83e-1)" "unprognostic (8.74e-2)" "unprognostic (3.74e-1)" "unprognostic (1.79e-2)" 0.8 0.2 0.0 2.5 0.0 25.9 0.1 0.0 0.3 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.7 0.3 0.0 0.0 0.5 0.2 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.0 2.3 0.3 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 11.5 2.3 2.8 0.0 0.0 0.0 0.4 0.8 0.0 1.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 3.3 0.0 0.9 0.0 0.0 1.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 CCN1 "CYR61, GIG1, IGFBP10" ENSG00000142871 "Cellular communication network factor 1" O00622 1 85580761-85584589 "Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Growth factor binding, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 256.5;Cardiomyocytes: 107.6;Cytotrophoblasts: 258.1;Extravillous trophoblasts: 529.9;Fibroblasts: 296.2;Syncytiotrophoblasts: 131.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebral cortex: 25.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 431.8;BJ hTERT+ SV40 Large T+: 422.0;EFO-21: 410.9;SiHa: 551.2;TIME: 541.3;U-251 MG: 642.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029853 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA029853: AB_10611822" "unprognostic (6.09e-2)" "unprognostic (3.25e-2)" "unprognostic (9.97e-2)" "unprognostic (8.90e-2)" "unprognostic (1.80e-2)" "unprognostic (3.91e-2)" "unprognostic (3.47e-2)" "unprognostic (1.56e-2)" "unprognostic (2.59e-1)" "unprognostic (9.95e-2)" "unprognostic (1.35e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.04e-3)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (3.74e-3)" 571.1 99.7 1.0 28.2 3.9 0.2 313.4 1.0 25.0 255.7 9.6 197.1 5.1 273.6 0.1 48.7 472.4 64.8 400.6 3.7 0.0 212.8 200.5 407.8 3.8 4.9 3.8 123.1 70.7 14.8 56.0 29.8 3.1 157.3 1.7 1.1 94.2 2.9 97.8 197.1 102.0 141.7 0.0 131.2 201.7 20.1 5.1 11.1 268.1 17.3 0.0 264.4 150.8 3.6 159.3 5.2 0.7 1.0 47.4 90.6 77.4 431.8 216.6 422.0 264.6 24.1 4.3 0.0 410.9 185.5 82.8 36.3 15.9 33.4 164.4 0.7 6.9 0.3 6.8 0.7 245.2 3.7 0.2 39.9 6.9 121.2 50.1 13.4 366.0 0.1 1.6 0.0 150.3 0.8 0.3 0.7 24.9 1.8 42.2 0.4 94.9 0.7 166.0 2.5 0.4 4.0 551.2 17.7 62.1 4.9 16.5 0.8 541.3 272.3 213.3 82.2 642.6 0.3 0.7 1.8 1.9 0.2 73.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.9 1.0 25.0 3.7 0.0 4.9 3.8 3.1 0.0 5.1 3.6 256.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.6 0.0 0.0 0.0 0.0 258.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 529.9 296.2 0.0 0.0 0.0 0.0 0.0 0.0 40.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 89.1 0.0 0.0 0.0 0.0 131.3 0.0 0.0 0.0 0.0 CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.5;Langerhans cells: 259.6;Melanocytes: 200.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 607.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA034986: AB_10602207, HPA061792: AB_2732670" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-3)" "unprognostic (7.30e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-1)" "unprognostic (4.53e-2)" 55.2 10.3 4.4 21.9 5.4 86.5 38.8 0.4 24.8 50.5 22.2 42.4 6.1 92.7 10.7 21.1 24.3 21.2 59.6 7.2 6.9 24.4 9.0 29.3 25.5 2.8 3.9 23.8 27.2 8.3 6.8 26.3 5.9 93.4 20.6 15.4 14.6 107.0 57.7 15.1 17.3 96.4 2.2 26.8 14.4 41.9 5.5 36.2 15.9 22.0 23.4 45.4 20.3 3.3 100.2 38.0 21.6 1.2 80.6 42.2 33.8 84.2 221.1 127.5 92.2 69.8 39.3 17.6 66.5 198.9 39.2 47.1 27.1 99.6 129.4 68.2 9.5 31.6 37.5 0.0 156.1 7.1 1.8 129.6 91.7 110.1 243.2 206.6 75.6 7.0 5.0 13.8 607.0 0.8 3.4 59.3 44.1 1.2 23.5 2.8 163.8 9.3 93.1 47.4 23.7 69.9 41.6 29.7 50.2 37.7 9.9 58.8 57.5 152.3 40.0 40.2 86.9 27.0 37.9 5.9 63.1 48.4 215.4 54.6 88.2 6.9 69.4 56.7 74.6 24.9 44.5 60.2 30.9 11.0 14.3 37.3 189.4 38.3 119.5 0.9 35.8 61.5 4.4 5.4 0.4 24.8 7.2 6.9 2.8 3.9 5.9 2.2 5.5 3.3 233.5 6.4 50.4 1.6 50.3 37.1 137.3 81.4 5.7 12.3 31.9 40.1 97.5 12.8 28.9 31.3 35.5 30.8 63.8 7.8 9.8 20.8 51.7 49.6 24.4 113.9 41.2 14.5 15.6 15.9 68.2 29.7 14.3 33.6 129.6 9.2 83.2 1.5 12.2 101.0 34.9 59.6 32.6 44.1 259.6 158.0 15.2 86.0 200.9 9.4 78.6 27.5 106.1 4.0 0.5 24.9 3.0 126.7 43.4 32.7 1.1 5.0 73.3 13.2 0.0 29.2 29.4 67.2 13.6 3.1 13.5 12.0 97.7 1.4 6.0 38.5 CDH11 "CAD11, OB" ENSG00000140937 "Cadherin 11" P55287 16 64943753-65126112 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 178.2;placenta: 122.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.0;Endometrial stromal cells: 125.0;Excitatory neurons: 122.2;Fibroblasts: 102.2;Microglial cells: 145.2;Oligodendrocyte precursor cells: 158.3;Oligodendrocytes: 106.3;Theca cells: 160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 246.5;BJ hTERT+: 139.3;fHDF/TERT166: 332.3;HSkMC: 217.4;PC-3: 291.2;U-2197: 194.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013072 Enhanced NA Yes 4800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB013072: AB_2533068" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (6.75e-2)" "prognostic unfavorable (2.48e-9)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (1.26e-1)" "unprognostic (5.07e-3)" 15.1 8.6 12.4 25.7 27.9 0.3 10.7 10.8 15.8 57.7 13.8 11.4 7.0 52.8 9.5 7.4 12.5 58.6 10.2 19.2 21.4 10.2 1.8 45.6 17.5 17.1 24.1 178.2 3.4 2.6 10.4 122.2 17.3 20.0 12.2 14.0 12.7 24.3 2.6 10.9 8.9 54.3 21.1 89.3 11.8 8.0 19.3 3.7 8.1 3.1 13.0 47.6 13.6 21.4 0.2 0.0 51.4 0.1 35.7 77.5 0.3 246.5 139.3 61.0 34.5 4.6 0.2 0.0 0.0 332.3 0.0 0.1 0.1 1.7 43.4 0.0 2.1 0.0 1.4 0.0 29.7 0.0 14.4 217.4 0.1 74.7 14.9 0.0 17.4 0.0 0.0 0.0 33.1 0.3 0.1 0.3 19.2 37.4 291.2 0.8 38.0 0.0 0.0 0.0 0.8 36.0 0.1 0.3 0.2 64.5 0.3 0.1 0.0 124.4 17.2 194.0 70.1 0.0 0.0 0.1 21.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 27.9 10.8 15.8 19.2 21.4 17.1 24.1 17.3 21.1 19.3 21.4 11.4 3.2 0.0 93.0 0.1 3.8 1.0 7.9 0.0 19.9 1.0 7.4 3.1 1.5 3.3 0.0 0.0 2.6 0.2 0.1 0.0 0.1 2.7 3.9 125.0 17.8 0.0 2.7 122.2 0.0 2.3 102.2 0.5 2.7 0.0 60.0 68.9 0.0 4.7 0.0 67.6 0.6 0.0 0.6 6.9 4.2 52.5 0.9 5.4 145.2 0.0 41.9 0.0 158.3 106.3 0.8 0.0 77.5 0.0 1.6 0.0 1.4 0.4 2.1 26.3 12.8 38.0 1.7 1.1 0.5 3.1 5.6 1.1 160.2 0.3 0.5 CDH2 "CD325, CDHN, NCAD" ENSG00000170558 "Cadherin 2" P19022 18 27932879-28177946 "CD markers, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 196.0" "Cell type enhanced" "Detected in many" "Astrocytes: 217.7;Cardiomyocytes: 368.8;Excitatory neurons: 311.2;Granulosa cells: 312.5;Inhibitory neurons: 198.2;Muller glia cells: 157.9;Oligodendrocyte precursor cells: 267.9" "Cancer enhanced" "Detected in all" "glioma: 39.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.7;neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Cell line enhanced" "Detected in many" "AF22: 278.2;BJ: 230.7;fHDF/TERT166: 459.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000141, CAB018580, HPA058574, CAB078686" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 160000000 "Cluster 10: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB000141: , CAB018580: AB_626778, CAB078686: AB_2665849, HPA058574: AB_2683760" "unprognostic (9.42e-2)" "unprognostic (2.69e-3)" "unprognostic (9.07e-3)" "unprognostic (5.45e-2)" "unprognostic (1.14e-1)" "unprognostic (9.30e-2)" "unprognostic (3.97e-2)" "unprognostic (2.53e-3)" "unprognostic (6.70e-3)" "unprognostic (1.00e-2)" "unprognostic (7.53e-2)" "unprognostic (3.51e-2)" "unprognostic (3.02e-2)" "unprognostic (1.93e-3)" "unprognostic (6.69e-2)" "unprognostic (1.33e-1)" "unprognostic (2.59e-3)" 0.6 66.5 27.4 2.6 29.0 0.2 0.3 20.6 31.6 6.6 7.9 4.8 0.8 6.2 1.1 0.4 10.5 3.1 196.0 30.0 31.6 18.1 57.2 1.0 1.9 21.7 26.3 6.7 0.9 29.8 8.1 0.4 20.1 2.4 1.1 60.3 0.4 10.8 0.4 0.3 1.4 6.8 24.1 13.5 5.9 44.4 33.3 3.8 6.2 2.2 1.6 1.1 2.7 22.7 0.3 25.8 278.2 0.3 48.1 7.8 0.2 230.7 72.0 94.9 80.8 0.1 0.4 0.0 128.3 459.1 46.0 36.7 50.0 0.2 130.4 0.4 35.8 0.0 66.8 86.7 48.0 0.0 0.1 4.6 0.4 198.6 37.4 212.9 84.0 15.4 0.0 0.1 77.8 0.0 59.4 0.1 43.8 0.1 30.5 0.2 37.1 45.6 0.1 9.9 83.4 144.4 0.1 0.2 26.8 116.8 0.3 0.5 11.6 206.6 63.6 2.9 181.6 0.2 0.3 0.3 40.6 0.2 163.0 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 27.4 29.0 20.6 31.6 30.0 31.6 21.7 26.3 20.1 24.1 33.3 22.7 0.8 0.0 0.6 217.7 1.2 0.3 0.0 3.4 0.0 38.7 1.6 0.4 368.8 67.2 1.2 11.0 150.1 0.1 0.0 0.0 0.0 12.9 53.2 1.4 15.2 9.8 0.0 6.1 311.2 0.4 0.0 16.7 0.0 2.6 0.0 312.5 12.5 125.3 0.3 3.3 198.2 0.0 2.0 2.2 0.4 17.7 2.1 1.2 3.6 106.8 0.1 157.9 0.0 267.9 138.6 19.2 0.0 12.8 0.0 0.1 0.0 47.5 1.7 99.9 6.6 0.4 45.8 4.8 24.1 0.0 0.0 0.3 0.6 1.6 0.0 0.1 CDX1 ENSG00000113722 "Caudal type homeobox 1" P47902 5 150166778-150184558 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "intestine: 131.3" "Group enriched" "Detected in some" 4 "Distal enterocytes: 349.6;Intestinal goblet cells: 193.4;Paneth cells: 295.0;Proximal enterocytes: 196.8;Undifferentiated cells: 312.5" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 125.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ hTERT+: 6.7;SuSa: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA055196 Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055196: AB_2682734" "unprognostic (2.50e-3)" "unprognostic (3.90e-1)" "unprognostic (1.65e-2)" "unprognostic (1.09e-2)" "unprognostic (5.89e-2)" "unprognostic (1.54e-2)" "unprognostic (2.07e-2)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (7.20e-2)" "unprognostic (1.59e-1)" "unprognostic (2.96e-1)" "unprognostic (1.83e-7)" "unprognostic (2.10e-1)" "unprognostic (4.25e-1)" "unprognostic (5.42e-3)" "unprognostic (2.16e-3)" 0.3 0.0 0.1 9.6 0.1 0.0 0.7 0.1 0.4 0.7 0.1 131.3 63.9 0.5 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 1.2 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.1 124.4 0.0 0.1 0.5 0.0 0.3 94.5 5.2 0.1 0.1 0.5 2.4 0.2 0.1 0.1 0.0 1.7 0.2 0.4 0.2 0.0 0.0 0.0 0.0 1.0 0.5 0.2 0.0 6.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.2 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 349.6 0.0 0.0 0.1 0.0 0.5 0.1 59.5 0.0 0.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 193.4 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 295.0 1.5 0.0 0.0 196.8 0.2 0.0 0.0 0.0 0.0 1.6 2.8 15.3 0.0 0.3 0.1 0.8 0.1 312.5 0.0 CEMIP "HYBID, IR2155535, KIAA1199, TMEM2L" ENSG00000103888 "Cell migration inducing hyaluronidase 1" Q8WUJ3 15 80779343-80951776 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 25.3;endometrium 1: 31.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 62.5;Inhibitory neurons: 40.0;Microglial cells: 101.2" "Cancer enhanced" "Detected in all" "colorectal cancer: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 204.1;BJ hTERT+: 321.8;fHDF/TERT166: 258.7;HSkMC: 169.3;hTERT-RPE1: 187.6;U-138 MG: 90.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 1700000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.14e-3)" "unprognostic (6.80e-2)" "unprognostic (5.95e-2)" "unprognostic (3.15e-3)" "unprognostic (3.49e-3)" "unprognostic (6.80e-2)" "unprognostic (5.47e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (1.53e-1)" "unprognostic (7.24e-2)" "unprognostic (1.36e-1)" "unprognostic (5.27e-10)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.65e-4)" 5.7 1.7 1.6 11.2 8.8 1.5 0.8 5.5 11.1 13.3 25.3 1.3 0.8 31.9 6.9 6.4 6.2 2.1 1.9 2.4 3.5 0.9 0.8 15.0 9.5 3.0 1.7 4.7 1.0 1.5 8.0 2.6 2.4 2.0 1.8 4.1 1.9 1.6 0.4 5.9 1.6 0.6 5.1 1.8 0.9 2.9 4.4 0.3 3.9 0.0 4.7 14.0 2.6 3.1 0.7 7.7 1.5 1.1 0.5 2.8 0.9 204.1 321.8 5.4 4.1 2.4 1.0 1.0 0.6 258.7 0.9 4.9 0.0 0.7 1.1 0.6 1.9 0.7 1.3 17.1 1.9 0.5 1.0 169.3 0.2 39.6 0.2 187.6 0.0 1.0 1.0 0.8 4.8 4.7 0.7 0.5 1.0 68.9 9.2 1.2 0.3 0.9 0.0 3.5 12.7 0.4 3.5 0.5 17.7 2.7 1.0 0.4 1.0 90.6 0.9 6.8 3.5 0.8 0.7 1.2 9.6 1.8 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.6 8.8 5.5 11.1 2.4 3.5 3.0 1.7 2.4 5.1 4.4 3.1 0.1 0.0 1.5 2.9 0.1 0.0 0.3 0.0 11.4 2.9 0.0 0.1 1.2 0.0 4.3 0.0 6.2 0.2 0.0 1.1 0.0 0.1 1.0 0.7 4.3 1.6 4.8 0.0 62.5 0.4 0.2 4.3 0.0 7.0 1.3 0.1 0.4 0.0 0.4 3.3 40.0 0.5 0.0 0.0 0.0 0.6 0.3 0.9 0.0 101.2 0.0 0.4 0.0 6.6 8.2 0.7 0.1 0.0 0.1 2.7 0.0 0.1 0.0 3.0 0.0 0.4 0.8 0.2 0.7 1.0 0.0 0.3 0.1 0.1 0.8 0.9 CENPT "C16orf56, CENP-T, FLJ13111" ENSG00000102901 "Centromere protein T" Q96BT3 16 67828157-67847811 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Spermatocytes: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041220, HPA058036" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear bodies" Nucleoplasm "HPA041220: AB_2677367, HPA058036: AB_2683585" "unprognostic (9.84e-2)" "unprognostic (2.86e-2)" "unprognostic (3.04e-2)" "unprognostic (8.77e-2)" "unprognostic (3.14e-2)" "unprognostic (6.66e-3)" "unprognostic (1.18e-2)" "unprognostic (2.81e-1)" "unprognostic (8.04e-2)" "unprognostic (3.15e-2)" "prognostic favorable (2.96e-4)" "unprognostic (6.64e-3)" "prognostic unfavorable (1.57e-7)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (9.23e-2)" "unprognostic (9.74e-3)" 7.0 5.6 7.2 3.1 7.1 5.3 6.4 7.4 10.0 7.9 5.7 8.1 2.4 7.0 1.4 6.6 7.3 1.8 8.0 7.4 7.8 6.3 5.3 6.3 3.6 7.5 7.3 7.7 9.6 4.9 4.3 4.2 7.6 6.5 2.0 0.8 5.8 4.3 8.2 24.8 6.3 4.7 6.8 5.5 7.4 19.6 7.3 4.4 5.1 5.6 2.3 7.3 6.9 7.2 7.6 7.4 10.0 10.2 8.1 7.8 14.7 29.5 13.6 30.2 24.1 7.9 5.6 3.3 7.1 19.8 5.3 12.4 7.5 13.2 10.3 5.3 9.5 1.2 3.2 11.3 5.1 0.6 6.9 8.5 7.7 20.7 4.4 4.4 12.3 8.1 19.3 3.6 14.5 11.9 9.8 10.7 13.5 5.9 7.1 13.4 4.5 17.6 11.2 3.1 3.9 6.8 22.2 4.6 5.8 6.3 6.1 10.0 9.7 4.3 7.4 6.6 7.0 7.0 5.8 19.4 3.3 6.1 7.4 1.4 7.2 6.3 6.5 6.6 7.0 4.9 6.0 8.2 6.0 6.1 5.3 7.0 3.4 5.4 4.3 6.0 8.5 5.1 7.2 7.1 7.4 10.0 7.4 7.8 7.5 7.3 7.6 6.8 7.3 7.2 21.0 16.0 11.3 10.4 17.4 21.0 20.2 24.4 12.5 24.9 20.3 19.3 8.2 14.3 17.2 20.2 8.4 31.5 25.4 27.5 5.9 19.0 52.2 8.8 17.8 19.7 13.1 30.3 16.9 14.2 25.0 23.0 34.1 11.2 8.2 20.9 17.5 9.4 15.2 25.2 12.3 11.3 24.4 8.5 17.8 47.9 24.2 17.9 17.8 7.5 9.8 13.7 21.6 12.1 8.4 19.7 17.8 22.2 26.9 11.1 16.3 10.3 12.2 10.5 26.3 19.9 25.1 89.8 33.5 12.8 19.5 30.1 22.6 24.3 13.7 13.6 CEP89 "CCDC123, FLJ14640" ENSG00000121289 "Centrosomal protein 89" Q96ST8 19 32875925-32971991 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039382, HPA040056" Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane" "HPA039382: AB_2676479, HPA040056: AB_10671048" "unprognostic (4.23e-2)" "unprognostic (7.50e-3)" "unprognostic (1.97e-1)" "unprognostic (1.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.78e-5)" "unprognostic (1.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.04e-2)" "unprognostic (1.80e-2)" "unprognostic (4.00e-2)" "unprognostic (1.74e-1)" "unprognostic (4.48e-2)" "unprognostic (6.53e-2)" "unprognostic (3.03e-1)" "unprognostic (2.47e-2)" 6.0 6.0 6.3 5.3 6.7 4.7 6.4 7.7 6.4 9.1 7.7 8.9 4.0 9.8 6.7 6.3 8.9 5.1 6.2 6.6 6.9 8.6 3.3 5.7 6.0 5.8 5.6 10.1 6.1 7.0 9.3 5.3 4.7 12.5 4.4 7.4 6.7 5.9 5.9 6.6 6.7 6.9 4.0 6.4 6.2 4.2 7.3 6.2 7.5 4.3 4.3 8.0 6.8 6.0 19.1 25.7 17.1 14.7 9.1 11.0 9.9 14.7 9.8 25.5 19.4 9.3 11.2 7.6 7.8 15.1 14.4 10.5 16.9 11.9 17.6 20.2 10.4 5.9 18.5 8.9 7.2 8.3 5.7 13.3 16.2 24.1 16.2 10.4 19.5 10.4 9.2 11.0 12.3 14.2 9.4 6.4 7.3 10.4 8.0 10.4 9.2 6.6 11.9 10.3 24.1 17.7 15.1 10.3 8.8 10.3 7.7 6.7 12.6 18.4 16.1 16.0 15.3 5.3 9.1 7.0 15.8 7.8 14.0 12.8 3.1 1.6 2.7 4.6 4.9 3.3 2.9 2.4 1.8 5.7 2.8 3.3 3.7 2.1 2.4 3.7 3.4 1.7 6.3 6.7 7.7 6.4 6.6 6.9 5.8 5.6 4.7 4.0 7.3 6.0 12.7 28.9 16.0 17.3 9.5 5.1 11.5 14.5 8.0 16.3 11.7 11.8 17.5 10.0 19.0 20.2 18.8 9.3 9.6 8.0 11.7 19.1 15.1 49.2 24.9 14.8 9.7 13.3 17.2 16.6 11.2 17.7 10.7 17.3 17.1 21.1 14.6 5.6 11.8 20.2 13.6 9.7 8.2 5.3 5.1 8.5 16.1 8.9 5.4 14.0 9.8 9.6 10.3 9.5 15.9 15.1 5.2 12.8 5.4 6.7 9.9 16.3 48.3 38.6 0.0 17.5 16.1 20.3 13.8 7.5 4.5 4.2 9.0 12.7 8.6 6.6 CFAP299 C4orf22 ENSG00000197826 "Cilia and flagella associated protein 299" Q6V702 4 80335730-80963750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "fallopian tube: 19.8;testis: 27.4" "Cell type enriched" "Detected in some" 54 "Endometrial ciliated cells: 54.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.4;BJ: 1.6;hTERT-RPE1: 2.5;LHCN-M2: 1.0;SCLC-21H: 1.1;U-251 MG: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043383 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA043383: AB_10797140" "unprognostic (4.77e-4)" "unprognostic (1.52e-1)" "unprognostic (4.06e-2)" "unprognostic (1.45e-2)" "unprognostic (7.24e-2)" "unprognostic (3.27e-1)" "unprognostic (6.93e-2)" "unprognostic (5.90e-2)" "unprognostic (2.67e-3)" "unprognostic (1.47e-1)" "unprognostic (2.79e-1)" "unprognostic (1.79e-2)" "unprognostic (4.61e-2)" 0.1 0.0 0.9 0.0 1.0 0.0 0.1 1.4 0.5 0.7 2.6 0.1 0.1 0.2 0.0 0.0 19.8 0.1 0.0 1.0 1.0 0.3 0.0 1.4 0.1 5.3 3.7 0.1 0.0 0.0 0.1 0.0 2.3 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 27.4 1.2 0.1 0.6 0.0 0.0 0.0 0.0 1.1 1.4 0.0 0.0 0.0 0.1 0.7 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 1.0 1.4 0.5 1.0 1.0 5.3 3.7 2.3 3.5 1.2 1.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 54.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 CFL1 CFL ENSG00000172757 "Cofilin 1" P23528 11 65823022-65862026 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013086, CAB033687, CAB037077, HPA053761" Approved Supported Cytosol NA NA 290000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "CAB013086: AB_2533565, CAB033687: AB_1121774, CAB037077: AB_1078547, HPA053761: AB_2682251" "unprognostic (1.14e-1)" "unprognostic (2.37e-2)" "unprognostic (7.69e-3)" "unprognostic (4.32e-3)" "unprognostic (3.14e-2)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (1.59e-3)" "unprognostic (2.52e-1)" "unprognostic (5.88e-3)" "unprognostic (6.57e-3)" "unprognostic (2.09e-1)" "unprognostic (6.19e-3)" "unprognostic (1.72e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (2.06e-1)" 609.5 435.4 578.8 932.7 598.8 1322.1 514.5 590.1 661.2 451.5 475.3 1145.1 1169.2 713.1 343.2 706.0 481.5 413.6 501.9 637.3 599.8 612.5 471.0 683.4 987.6 626.4 571.5 344.7 264.6 301.8 340.6 479.2 622.1 440.6 990.3 208.9 453.1 457.6 261.9 503.1 1120.7 847.3 608.3 775.2 633.8 267.4 632.2 939.6 370.9 230.6 1100.5 682.9 471.2 695.4 2284.3 1783.6 1908.5 1529.8 1142.6 1157.0 1031.6 2309.7 1942.4 2457.5 1460.7 1012.4 1815.2 1700.8 1755.3 2925.7 1780.5 1623.2 1389.2 2103.8 1824.9 1869.0 718.2 2185.8 1271.2 1162.1 1222.6 1890.2 2854.6 1339.3 1412.4 2166.7 1108.0 1494.0 2663.1 1099.4 1037.6 1648.5 2635.7 2133.0 2739.4 2965.4 2095.8 1985.4 1432.7 2050.3 941.1 2181.9 1847.8 1468.6 952.7 2106.6 1250.6 1733.6 1682.2 1053.4 2104.1 1427.8 2330.5 2087.3 1603.5 2672.6 2194.0 1193.1 2065.2 2251.0 2146.2 1161.7 2004.4 1690.2 2720.0 2973.1 2534.0 2955.4 1964.6 1561.4 1992.5 2296.2 3343.8 1527.0 1459.3 1905.2 2946.2 1961.1 3255.3 2558.6 2696.1 6842.2 578.8 598.8 590.1 661.2 637.3 599.8 626.4 571.5 622.1 608.3 632.2 695.4 805.5 246.8 223.0 24.5 890.8 1349.3 1253.3 1197.1 598.8 198.5 655.2 646.0 74.8 459.0 595.7 520.5 58.4 1239.8 1439.8 2052.9 892.1 2114.0 459.4 376.6 648.1 918.4 779.0 557.7 38.8 1965.0 2470.6 579.0 642.8 603.3 598.2 527.4 698.2 436.3 2911.0 203.6 30.3 1448.8 891.1 1185.5 1706.6 373.2 352.2 1474.2 985.4 38.4 2903.8 478.3 2075.2 22.6 62.0 3082.4 1894.7 502.9 639.1 991.2 2279.4 1246.5 295.5 118.0 420.7 448.2 1184.3 177.4 412.8 703.8 1267.4 1732.4 1276.2 621.7 1315.3 1383.3 CFL2 NEM7 ENSG00000165410 "Cofilin 2" Q9Y281 14 34709113-34714823 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 372.8;skeletal muscle: 719.9;tongue: 686.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 522.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037078, HPA045599" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 47000000 "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB037078: AB_259128, HPA045599: AB_2679383" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.02e-2)" "unprognostic (2.80e-3)" "unprognostic (3.82e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-1)" "unprognostic (2.92e-2)" "unprognostic (2.48e-2)" "unprognostic (1.27e-1)" "unprognostic (1.65e-2)" "unprognostic (3.13e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (2.16e-5)" 48.7 52.5 71.7 28.6 98.7 18.1 24.6 90.3 116.1 39.8 53.9 92.5 14.3 73.4 19.5 69.0 42.6 24.1 372.8 69.4 85.0 31.4 125.9 24.9 10.7 85.7 83.6 41.2 9.4 24.4 10.9 35.3 88.7 75.4 28.1 41.0 17.1 107.3 719.9 8.2 24.0 115.0 74.7 12.7 36.1 21.7 81.2 10.4 29.4 686.4 9.9 56.8 24.3 130.5 87.1 77.7 49.5 32.0 51.1 185.6 27.9 146.6 170.5 145.6 151.4 61.9 38.5 30.6 58.5 245.2 104.9 17.1 107.4 32.5 268.6 4.2 45.0 6.6 87.4 144.5 81.6 8.2 5.3 139.3 12.4 122.2 67.7 96.8 145.9 4.5 9.9 26.8 186.9 25.5 6.3 4.3 16.3 15.4 118.9 5.4 158.1 4.7 55.1 17.7 10.3 41.7 96.6 21.5 51.2 36.2 47.8 7.5 124.6 140.9 93.0 66.1 72.9 34.3 22.8 11.7 51.7 11.4 34.5 1.8 1.0 1.3 1.9 1.0 3.1 4.9 2.2 2.1 1.6 3.0 1.7 1.8 0.3 1.8 0.4 1.6 2.1 0.9 71.7 98.7 90.3 116.1 69.4 85.0 85.7 83.6 88.7 74.7 81.2 130.5 39.6 105.8 41.6 6.2 17.0 20.0 88.6 31.3 23.9 62.8 19.6 16.6 522.2 22.8 26.3 22.0 20.9 32.2 11.5 0.9 60.7 45.2 2.6 40.3 60.5 45.1 9.5 11.4 9.6 39.7 60.5 69.9 6.1 56.2 5.7 25.8 47.2 112.0 15.6 77.4 14.2 2.4 57.0 15.7 14.4 10.1 57.2 10.6 30.2 11.2 5.7 112.9 15.5 8.0 93.8 24.7 4.0 98.6 60.4 84.0 1.0 101.9 24.7 57.8 32.9 83.9 115.8 49.3 51.9 16.1 19.5 21.3 21.1 47.9 4.6 58.5 CH25H ENSG00000138135 "Cholesterol 25-hydroxylase" O95992 10 89205629-89207317 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.3" "Cell type enhanced" "Detected in many" "Adipocytes: 125.9;Basal squamous epithelial cells: 224.3;Macrophages: 47.3;Microglial cells: 40.3;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 8.8;ASC TERT1: 4.4;fHDF/TERT166: 32.8;HSkMC: 8.2" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "spinal cord: 6.3" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "unprognostic (6.07e-3)" "unprognostic (2.96e-3)" "unprognostic (1.57e-1)" "unprognostic (5.11e-2)" "unprognostic (2.17e-2)" "unprognostic (2.02e-1)" "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "unprognostic (8.65e-3)" "unprognostic (7.74e-2)" "unprognostic (4.76e-2)" "unprognostic (2.62e-5)" "unprognostic (2.47e-2)" "unprognostic (1.40e-1)" "unprognostic (2.32e-2)" "unprognostic (2.29e-2)" 21.5 5.1 4.3 7.0 5.0 3.1 7.4 6.5 6.6 3.5 4.4 3.6 3.2 1.3 12.6 14.7 6.0 14.6 4.5 4.2 8.4 7.8 3.6 17.2 4.0 18.4 9.5 2.1 1.6 1.1 9.0 4.2 11.4 4.1 5.5 0.4 2.1 1.3 1.8 3.0 5.6 5.5 8.6 2.0 5.8 0.1 6.0 35.3 2.8 1.0 3.7 18.5 2.1 8.2 0.0 0.0 0.0 0.0 8.8 4.4 0.0 0.1 3.1 0.8 0.9 0.0 0.0 0.0 1.1 32.8 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.8 0.0 0.0 8.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 4.2 0.0 0.2 0.0 0.1 0.0 0.0 3.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.0 6.5 6.6 4.2 8.4 18.4 9.5 11.4 8.6 6.0 8.2 125.9 3.2 3.4 0.3 1.8 6.9 4.4 11.7 224.3 0.0 6.4 1.0 0.6 0.0 10.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 1.5 0.9 23.6 0.0 0.0 2.9 0.0 0.2 33.4 2.0 3.1 1.3 0.0 2.5 0.0 10.2 1.7 0.5 0.0 2.0 12.9 8.2 0.0 0.3 47.3 7.2 40.3 0.0 0.6 0.0 0.0 0.4 0.1 0.0 0.7 4.4 1.0 0.0 0.0 4.5 0.5 6.6 3.6 59.3 0.0 0.0 30.8 6.7 0.1 11.6 0.5 0.0 6.2 CHMP6 "FLJ11749, VPS20" ENSG00000176108 "Charged multivesicular body protein 6" Q96FZ7 17 80991598-81009517 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023001, HPA024460" Approved NA NA 17000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023001: AB_1848689, HPA024460: AB_1848691" "unprognostic (6.05e-3)" "unprognostic (2.25e-2)" "unprognostic (7.21e-3)" "unprognostic (2.26e-1)" "unprognostic (3.54e-2)" "unprognostic (3.41e-1)" "unprognostic (5.96e-2)" "unprognostic (1.74e-1)" "unprognostic (9.29e-2)" "unprognostic (1.46e-1)" "prognostic favorable (9.99e-4)" "unprognostic (5.67e-2)" "unprognostic (3.74e-2)" "unprognostic (1.57e-1)" "unprognostic (1.61e-1)" "unprognostic (2.00e-2)" "unprognostic (2.40e-3)" 18.9 18.1 13.4 13.5 13.0 8.9 19.2 12.9 13.8 21.3 10.8 21.4 13.2 19.9 9.5 24.7 16.2 8.8 24.4 12.9 10.9 21.4 35.4 17.8 14.1 14.5 12.6 15.6 19.2 19.1 16.2 13.6 13.2 19.9 15.6 18.5 17.2 12.6 45.1 22.0 18.9 17.2 12.4 25.6 17.6 10.5 12.3 17.1 18.2 29.2 14.7 18.7 18.0 15.6 27.6 43.5 32.1 19.5 16.8 17.2 22.2 26.6 29.8 44.2 32.3 10.9 14.8 28.0 20.7 42.2 27.4 18.5 7.0 30.5 31.3 13.5 23.8 23.1 9.0 38.0 25.0 28.1 28.0 18.4 20.7 27.5 29.7 27.5 62.4 28.1 24.4 22.9 23.0 25.8 34.9 28.8 10.4 7.4 26.9 27.3 28.5 19.0 25.2 37.1 10.5 31.9 19.9 30.8 29.9 25.6 27.5 21.4 35.7 61.1 34.5 18.1 36.3 13.8 3.6 14.4 26.1 17.0 29.0 66.9 40.6 84.1 37.2 42.7 23.9 26.2 22.4 30.5 32.5 19.8 24.6 22.0 25.9 43.7 52.6 30.9 19.0 39.2 13.4 13.0 12.9 13.8 12.9 10.9 14.5 12.6 13.2 12.4 12.3 15.6 19.1 6.4 9.3 5.9 12.8 6.1 8.9 16.3 8.0 20.2 14.7 16.6 1.0 17.2 14.5 14.7 4.2 39.9 20.1 36.8 13.7 37.4 1.5 8.2 11.2 17.4 21.1 8.8 1.7 43.9 31.6 16.6 20.4 9.9 21.0 23.8 18.2 17.3 41.6 10.1 1.9 19.7 18.3 24.2 6.5 2.5 10.2 20.1 16.0 1.0 37.1 26.7 35.0 3.0 4.4 33.9 35.5 12.8 11.5 9.5 36.7 23.2 8.6 44.3 13.1 15.8 14.1 9.0 12.2 14.0 5.8 50.3 16.7 18.9 22.2 8.8 CHN1 "ARHGAP2, CHN, DURS2, n-chimerin, RhoGAP2" ENSG00000128656 "Chimerin 1" P15882 2 174798809-175005381 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 772.6" "Cell type enhanced" "Detected in many" "Astrocytes: 195.2;Excitatory neurons: 596.4;Inhibitory neurons: 111.7;Microglial cells: 97.4;Oligodendrocyte precursor cells: 149.8" "Cancer enhanced" "Detected in all" "glioma: 18.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 6.5;memory CD8 T-cell: 2.1;T-reg: 8.0" "Lineage enriched" "Detected in single" 18 "T-cells: 8.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 186.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036111 Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA036111: AB_10671241" "unprognostic (3.18e-3)" "unprognostic (4.19e-2)" "unprognostic (9.69e-2)" "unprognostic (3.42e-3)" "unprognostic (1.92e-1)" "unprognostic (2.65e-2)" "unprognostic (7.45e-2)" "unprognostic (9.14e-2)" "unprognostic (3.71e-2)" "unprognostic (1.34e-2)" "unprognostic (5.29e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (7.31e-3)" "unprognostic (4.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.46e-2)" 11.8 13.3 368.6 7.3 445.9 0.8 10.5 194.0 772.6 9.2 170.6 10.2 3.3 7.9 38.3 6.9 6.5 11.1 15.1 492.6 241.5 4.7 2.1 19.6 21.5 210.2 225.4 5.8 4.2 43.4 36.3 38.6 210.5 17.0 5.1 39.5 3.2 9.6 2.7 3.8 7.5 13.1 192.4 5.5 7.1 21.3 239.1 3.1 10.2 3.7 18.7 8.7 6.7 422.8 0.4 17.4 57.6 16.3 14.7 67.4 0.4 45.6 186.7 65.1 97.0 0.3 5.4 0.5 1.6 71.8 39.9 2.0 68.0 1.9 30.3 1.3 32.9 11.1 20.1 3.8 34.4 6.4 1.7 53.6 1.9 31.6 11.1 16.1 33.6 30.0 0.7 1.9 57.2 11.8 29.3 2.5 71.7 2.6 23.7 8.2 70.3 0.8 0.9 0.6 71.3 76.3 41.3 0.5 7.3 36.0 3.2 2.2 10.1 26.8 3.9 9.8 20.6 6.4 33.7 0.7 6.7 0.4 6.6 0.4 0.1 0.1 0.3 0.1 0.8 0.2 6.5 2.1 0.0 0.1 1.3 0.4 0.4 0.2 0.2 0.3 8.0 1.0 368.6 445.9 194.0 772.6 492.6 241.5 210.2 225.4 210.5 192.4 239.1 422.8 15.4 3.2 1.9 195.2 1.6 4.5 0.3 0.0 0.0 85.1 7.3 1.4 6.2 1.5 2.6 3.7 27.1 1.2 0.5 0.1 0.0 0.3 24.1 5.3 5.6 17.9 2.4 0.0 596.4 0.6 1.1 28.4 2.0 3.6 0.0 5.1 10.4 0.5 2.7 77.4 111.7 0.0 0.0 0.0 4.0 23.2 3.1 0.9 7.2 97.4 0.0 59.1 0.0 149.8 88.1 0.6 0.0 5.3 1.3 0.6 0.0 0.3 1.0 14.1 13.1 23.8 27.3 17.8 23.6 0.1 3.7 2.1 12.5 5.1 0.2 0.3 CHRM2 ENSG00000181072 "Cholinergic receptor muscarinic 2" P08172 7 136868652-137020255 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 36.1;intestine: 21.2" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 59.9;Excitatory neurons: 49.4;Inhibitory neurons: 119.2" "Cancer enhanced" "Detected in single" "stomach cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 86.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022338, HPA029795" Approved NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022338: , HPA029795: AB_10601357" "unprognostic (3.51e-2)" "unprognostic (3.73e-4)" "unprognostic (5.77e-2)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.00e-1)" "unprognostic (2.69e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-1)" "unprognostic (1.35e-3)" 0.1 0.2 2.8 1.3 2.0 0.1 0.0 0.1 2.3 0.3 0.0 21.2 0.7 0.4 0.0 0.3 0.3 10.7 36.1 0.1 2.5 0.0 1.1 0.8 0.0 9.3 5.4 0.2 0.1 0.0 0.0 1.4 9.1 0.2 3.5 0.8 0.0 0.0 0.0 0.1 4.4 9.7 1.8 0.0 5.9 0.6 6.8 0.1 0.0 0.0 0.0 8.9 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 17.6 0.2 0.0 0.0 0.0 0.0 0.0 86.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.0 0.1 2.3 0.1 2.5 9.3 5.4 9.1 1.8 6.8 1.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 59.9 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.2 0.2 0.0 0.0 49.4 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 119.2 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 CIDEA CIDE-A ENSG00000176194 "Cell death inducing DFFA like effector a" O60543 18 12254361-12277595 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 18 "adipose tissue: 221.3;breast: 108.0" "Cell type enriched" "Detected in some" 78 "Breast glandular cells: 330.6" "Cancer enhanced" "Detected in some" "breast cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "hTEC/SVTERT24-B: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "unprognostic (2.96e-2)" "unprognostic (2.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (8.93e-3)" "unprognostic (3.20e-2)" "unprognostic (7.00e-2)" "unprognostic (3.72e-2)" "unprognostic (1.91e-3)" "unprognostic (3.17e-2)" "unprognostic (7.67e-3)" "unprognostic (1.96e-1)" 221.3 3.7 2.3 0.2 3.2 0.0 108.0 2.8 5.2 3.5 1.7 1.5 0.0 0.0 0.0 4.8 0.0 1.2 1.9 2.7 1.8 0.2 0.2 0.0 0.3 2.4 2.2 0.0 0.9 0.0 0.0 0.0 2.7 0.1 0.9 0.1 4.3 0.0 1.0 9.3 2.1 0.2 2.2 0.0 1.0 0.1 2.0 0.2 0.5 4.6 0.2 1.1 5.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.2 2.8 5.2 2.7 1.8 2.4 2.2 2.7 2.2 2.0 3.0 1.9 0.0 0.0 0.7 0.5 0.1 0.1 0.3 0.0 0.2 330.6 3.8 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 1.0 0.0 0.2 0.3 0.0 0.0 3.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.2 0.6 0.6 1.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.4 0.3 0.7 1.0 0.0 0.3 0.5 0.0 0.8 CITED2 MRG1 ENSG00000164442 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2" Q99967 6 139371807-139374648 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Stress response, Transcription, Transcription regulation" "Activator, Developmental protein, Repressor" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 685.3;Plasma cells: 619.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 27.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 618.3;fHDF/TERT166: 1070.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016157, CAB069879" Supported Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "CAB016157: AB_668099, CAB069879: AB_10003446" "unprognostic (7.42e-2)" "unprognostic (2.06e-2)" "unprognostic (1.56e-2)" "unprognostic (8.34e-2)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-2)" "unprognostic (1.13e-1)" "unprognostic (4.05e-2)" "unprognostic (1.11e-2)" "unprognostic (3.61e-3)" "unprognostic (1.00e-2)" "prognostic favorable (3.40e-4)" "prognostic unfavorable (3.33e-4)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" "unprognostic (2.03e-1)" 177.7 107.4 3.8 49.8 2.2 313.6 117.5 29.3 24.0 60.5 5.4 88.0 36.7 188.0 38.7 75.5 207.7 32.6 70.9 1.9 9.3 70.7 203.4 134.0 37.9 8.5 6.5 270.3 74.7 179.0 17.7 104.1 8.3 44.2 42.5 36.4 120.5 42.8 107.6 131.7 65.3 81.9 0.9 136.5 69.5 22.0 19.4 25.1 227.7 24.9 30.4 37.9 64.0 0.7 23.7 13.7 46.7 138.2 191.8 203.7 175.6 618.3 456.0 274.7 255.7 122.5 35.2 17.0 88.5 1070.3 58.5 28.0 14.2 14.5 192.4 467.0 45.8 346.9 76.0 10.1 157.1 103.1 36.5 164.6 64.4 121.3 91.4 177.9 51.2 10.1 132.9 80.1 359.2 51.0 17.5 128.3 43.8 15.0 21.2 24.7 34.2 152.3 131.7 52.5 51.8 0.8 45.2 167.6 21.2 106.8 72.3 348.3 283.6 219.9 69.5 66.4 35.0 23.4 22.6 26.3 68.0 86.9 15.8 3.1 8.2 27.7 3.4 4.6 5.0 1.2 5.4 4.9 3.6 3.1 4.7 2.4 4.0 3.0 6.6 1.6 3.6 3.3 3.8 2.2 29.3 24.0 1.9 9.3 8.5 6.5 8.3 0.9 19.4 0.7 157.1 115.4 272.8 3.6 138.8 35.8 111.5 12.7 347.8 30.6 164.4 180.0 114.1 80.1 36.5 103.0 12.5 173.1 156.5 159.6 185.9 20.5 1.5 122.6 131.7 68.9 99.7 274.3 6.9 14.9 685.3 200.3 121.8 262.3 46.9 133.9 61.1 65.5 372.6 30.3 22.2 111.6 20.3 124.4 67.7 7.7 99.4 188.9 83.6 9.4 44.2 51.9 55.6 1.0 1.3 23.1 97.7 60.9 619.4 46.6 88.8 121.0 27.4 52.5 98.6 107.9 179.1 1.8 20.8 200.8 33.8 269.3 291.8 272.9 112.6 38.4 CKAP4 "CLIMP-63, ERGIC-63, P63" ENSG00000136026 "Cytoskeleton associated protein 4" Q07065 12 106237881-106304279 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 198.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 106.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 106.8" "Cell line enhanced" "Detected in many" "BJ: 549.7;BJ hTERT+: 687.6;fHDF/TERT166: 834.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000278, HPA000792" Enhanced NA NA 560000 "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "HPA000278: AB_1078527, HPA000792: AB_1078526" "unprognostic (5.25e-2)" "unprognostic (1.47e-1)" "unprognostic (1.91e-1)" "unprognostic (7.13e-2)" "unprognostic (2.44e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (6.61e-5)" "prognostic unfavorable (5.61e-4)" "unprognostic (5.02e-2)" "unprognostic (9.66e-3)" "unprognostic (1.95e-1)" "unprognostic (6.23e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.20e-3)" "unprognostic (6.97e-2)" "unprognostic (1.29e-2)" "unprognostic (3.66e-2)" 26.6 40.0 14.7 34.7 16.1 100.5 21.8 14.2 15.4 49.5 27.9 42.9 19.3 40.6 59.2 71.3 31.2 26.3 40.0 14.2 17.4 21.3 30.4 33.5 10.5 18.1 16.1 30.6 41.1 26.1 20.2 51.8 17.2 37.6 45.8 18.8 57.5 36.9 14.5 39.4 19.0 46.7 15.6 25.1 52.3 9.9 19.6 7.8 19.8 13.5 22.8 51.4 40.5 18.4 86.8 106.7 126.5 138.3 240.6 212.5 73.2 549.7 687.6 262.7 300.1 45.6 19.4 5.6 98.0 834.0 89.3 153.1 93.5 83.5 187.5 3.0 54.1 0.1 56.5 89.9 179.2 0.4 1.7 205.5 111.9 223.5 159.9 331.9 311.7 6.5 0.6 11.0 253.0 29.1 4.4 3.1 73.8 45.6 127.9 40.1 91.0 7.5 80.5 76.9 41.5 46.0 98.0 65.9 54.4 112.9 73.9 39.3 268.9 205.8 112.2 86.3 157.9 29.0 0.3 60.2 148.5 10.9 184.5 106.8 18.8 22.5 1.1 6.8 1.6 9.5 1.7 1.0 5.8 4.1 2.2 2.0 30.1 0.2 11.3 0.2 0.5 7.1 14.7 16.1 14.2 15.4 14.2 17.4 18.1 16.1 17.2 15.6 19.6 18.4 17.7 22.4 26.5 9.1 26.3 54.8 37.9 63.2 56.3 11.8 37.6 34.4 43.2 35.8 33.4 23.9 10.4 26.9 2.8 43.0 5.9 37.8 1.1 38.6 103.1 33.8 41.4 1.3 5.8 87.7 107.0 92.9 51.5 139.9 19.1 62.8 43.2 52.3 20.1 47.1 11.2 198.7 16.2 31.8 16.8 2.7 68.3 33.1 33.8 8.4 59.9 23.4 2.1 7.5 1.6 52.4 22.9 61.3 144.5 92.0 3.9 9.2 13.3 23.3 13.1 45.1 52.3 4.9 12.6 122.3 71.9 26.4 6.7 73.3 69.0 46.7 CLIC4 "CLIC4L, DKFZP566G223, H1, huH1, P64H1" ENSG00000169504 "Chloride intracellular channel 4" Q9Y696 1 24745382-24844321 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 346.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 13.4;naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008019, HPA060804" Enhanced Supported "Plasma membrane,Centrosome" NA NA 5800000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Centrosome" "HPA008019: AB_1846946, HPA060804: AB_2684370" "unprognostic (7.35e-3)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.54e-2)" "unprognostic (7.60e-2)" "unprognostic (2.92e-2)" "unprognostic (9.48e-2)" "unprognostic (6.78e-3)" "unprognostic (1.63e-2)" "unprognostic (5.50e-2)" "unprognostic (4.03e-3)" "unprognostic (1.98e-2)" "unprognostic (7.01e-2)" "prognostic favorable (1.48e-5)" "unprognostic (2.75e-3)" "unprognostic (2.17e-1)" "unprognostic (1.22e-2)" "unprognostic (3.82e-3)" 154.0 58.6 51.8 97.7 70.2 32.3 88.1 61.8 82.7 165.4 39.4 136.3 32.4 201.5 84.6 119.3 103.0 106.5 197.2 50.8 66.5 256.8 72.3 114.6 51.0 73.6 68.0 46.0 49.7 29.3 14.1 120.6 67.0 112.8 66.8 53.1 49.4 152.8 30.7 33.6 54.2 280.4 62.4 43.1 80.0 34.2 88.9 59.6 47.6 53.2 56.4 156.1 73.4 91.4 219.3 25.3 222.7 176.8 299.1 645.6 116.7 561.0 571.4 253.9 304.2 48.3 114.1 129.8 320.1 799.2 77.0 76.8 155.0 151.5 635.7 33.3 64.9 50.0 60.8 88.3 417.3 17.5 6.3 299.3 256.8 363.0 365.1 417.3 427.0 76.0 40.4 138.2 739.0 38.4 34.8 28.5 212.6 50.4 101.8 83.5 247.3 51.5 260.0 58.4 38.9 101.3 144.7 68.4 453.7 228.3 60.0 116.1 601.0 452.2 168.8 199.4 230.1 75.4 111.7 108.6 333.8 151.1 140.5 0.8 5.4 2.5 0.4 4.4 0.0 13.4 0.3 0.2 5.6 11.9 0.1 0.2 1.2 0.0 4.0 1.7 0.0 3.5 51.8 70.2 61.8 82.7 50.8 66.5 73.6 68.0 67.0 62.4 88.9 91.4 178.7 16.0 30.5 24.8 50.8 61.6 50.4 79.8 37.0 3.7 49.9 33.0 172.5 21.5 35.2 14.7 10.4 71.5 2.2 18.1 41.1 39.2 44.9 20.9 103.0 177.1 9.6 40.8 1.5 43.1 211.4 120.5 21.4 53.6 40.0 10.2 88.5 34.4 39.3 1.7 4.2 22.6 20.3 28.2 100.2 27.3 28.6 52.6 129.9 75.9 50.8 13.0 4.1 41.7 196.9 54.7 10.6 87.6 171.2 114.5 0.1 346.1 16.7 26.5 46.0 87.9 162.5 44.0 29.1 29.3 52.0 177.0 8.1 46.5 2.6 49.1 CLMP "ACAM, ASAM, FLJ22415" ENSG00000166250 "CXADR like membrane protein" Q9H6B4 11 123069872-123195248 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 63.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 75.7;Fibroblasts: 95.1;Inhibitory neurons: 31.9;Peritubular cells: 57.9;Skeletal myocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 124.8;BJ: 171.8;BJ hTERT+: 160.3;fHDF/TERT166: 126.6;hTEC/SVTERT24-B: 129.1;hTERT-HME1: 155.6;U-138 MG: 232.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.63e-2)" "unprognostic (6.65e-3)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (3.46e-2)" "unprognostic (9.42e-3)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (9.66e-3)" "unprognostic (3.25e-2)" "unprognostic (4.02e-3)" "unprognostic (3.87e-2)" "unprognostic (9.78e-8)" "unprognostic (3.88e-3)" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "unprognostic (1.69e-2)" 63.2 6.5 0.9 14.7 0.8 0.4 24.5 7.8 2.7 20.5 3.6 41.1 7.3 30.3 4.3 10.1 18.4 23.1 12.9 5.3 0.4 6.0 0.4 8.1 7.4 4.2 2.1 9.1 2.0 0.2 1.9 26.3 1.8 7.4 10.6 0.9 5.4 8.5 1.7 6.5 17.3 36.3 2.0 8.1 16.0 2.6 2.1 0.8 2.4 3.4 5.0 16.7 14.0 5.2 3.0 3.3 7.5 15.2 124.8 108.1 45.5 171.8 160.3 23.9 43.8 7.4 0.2 0.0 0.4 126.6 82.4 0.1 0.3 45.5 27.3 0.9 0.3 0.0 7.1 0.1 40.7 0.0 0.1 61.0 30.6 129.1 155.6 59.7 11.7 0.1 0.0 0.4 33.3 0.1 0.0 0.2 17.4 0.0 20.2 0.1 2.5 0.1 12.6 0.0 20.5 50.3 0.0 0.4 0.1 3.2 0.6 0.0 43.3 232.7 2.3 96.0 21.6 0.1 0.0 0.1 63.1 0.0 7.5 0.3 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.9 0.8 7.8 2.7 5.3 0.4 4.2 2.1 1.8 2.0 2.1 5.2 2.3 0.0 3.9 2.0 0.2 1.5 0.3 2.4 0.0 3.8 1.2 14.6 5.1 0.0 0.4 0.0 0.0 9.8 0.3 0.1 0.0 1.9 0.7 2.4 75.7 1.4 6.7 0.0 26.5 1.3 20.4 95.1 0.0 1.4 0.0 5.3 2.2 0.0 3.6 1.7 31.9 0.5 0.0 0.0 1.9 0.7 20.8 0.9 0.0 4.7 0.0 0.5 0.0 1.0 3.6 0.9 0.0 57.9 0.6 2.0 0.1 0.1 0.2 1.1 0.0 65.0 8.5 0.1 0.1 0.4 1.0 10.4 1.1 2.2 0.3 0.5 CLOCK "bHLHe8, KAT13D, KIAA0334" ENSG00000134852 "Clock circadian regulator" O15516 4 55427903-55546909 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001867, HPA027565" Supported Enhanced Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Nucleoplasm Vesicles "HPA001867: AB_1078537, HPA027565: AB_1846975" "unprognostic (1.30e-2)" "unprognostic (9.02e-2)" "unprognostic (4.25e-3)" "unprognostic (2.48e-1)" "unprognostic (3.94e-2)" "unprognostic (2.00e-2)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (4.52e-2)" "unprognostic (4.32e-2)" "unprognostic (3.01e-2)" "unprognostic (5.96e-2)" "unprognostic (4.07e-2)" "unprognostic (8.31e-2)" "unprognostic (1.69e-1)" "unprognostic (5.18e-2)" "unprognostic (7.16e-2)" 5.5 6.1 3.7 4.2 4.2 1.3 5.9 8.9 5.4 8.0 5.5 5.1 4.9 6.9 5.7 9.2 5.3 4.3 7.5 4.7 5.3 6.5 5.5 4.6 2.9 2.8 3.7 6.2 5.1 10.3 5.5 5.5 3.3 6.2 5.7 11.6 4.6 6.1 9.8 6.8 5.6 7.1 3.8 4.5 6.9 14.1 3.8 3.0 10.1 9.2 3.7 5.6 6.8 5.0 20.0 9.1 7.5 11.6 11.8 11.5 3.6 18.7 16.4 12.9 12.7 5.1 14.8 5.1 9.9 22.8 10.3 15.9 9.5 15.4 23.2 6.9 3.1 4.4 9.4 6.7 10.3 7.0 4.7 6.7 15.8 18.8 18.7 10.4 13.1 4.6 10.1 10.1 21.3 10.6 4.0 4.1 5.0 16.3 9.4 2.5 8.7 3.3 11.0 10.9 7.6 6.2 13.5 16.7 8.9 6.2 5.7 4.2 17.1 18.4 19.5 6.0 26.6 9.1 7.5 3.1 15.6 5.8 14.6 0.0 0.7 0.2 0.7 0.7 1.3 0.4 0.9 0.8 1.1 0.7 0.4 0.6 0.2 0.9 0.7 0.5 0.9 0.4 3.7 4.2 8.9 5.4 4.7 5.3 2.8 3.7 3.3 3.8 3.8 5.0 32.2 41.7 27.7 49.3 15.2 31.1 21.8 28.5 27.9 63.4 21.5 14.9 55.2 14.3 27.4 14.7 43.8 11.3 11.9 21.5 1.9 13.6 34.5 34.2 39.9 32.1 39.7 3.8 95.9 16.5 6.8 28.0 25.0 32.0 3.8 16.6 28.9 27.7 11.6 33.7 114.6 18.5 18.3 17.0 26.1 16.9 23.9 16.9 10.6 70.3 14.0 26.7 19.6 82.0 93.1 28.3 13.2 36.1 18.5 34.0 29.6 19.7 25.2 41.4 13.1 36.5 28.2 64.9 72.5 55.1 37.5 5.2 14.0 21.7 15.6 51.6 CNN1 "Sm-Calp, SMCC" ENSG00000130176 "Calponin 1" P51911 19 11538767-11550323 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 1872.4;intestine: 2657.3;smooth muscle: 2207.8" "Group enriched" "Detected in many" 5 "Breast myoepithelial cells: 191.0;Early spermatids: 335.0;Late spermatids: 554.6;Peritubular cells: 221.2;Smooth muscle cells: 180.9" "Cancer enhanced" "Detected in all" "prostate cancer: 142.1;stomach cancer: 103.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 91.5;BJ hTERT+: 34.9;BJ hTERT+ SV40 Large T+: 48.0;BJ hTERT+ SV40 Large T+ RasG12V: 64.6;HBF TERT88: 71.2;K-562: 35.8;SuSa: 72.5;U-2 OS: 34.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000007, HPA014263" Enhanced Approved "Actin filaments" No No "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Actin filaments" "CAB000007: AB_2082148, HPA014263: AB_1847039" "unprognostic (4.98e-3)" "unprognostic (1.01e-1)" "unprognostic (3.04e-3)" "unprognostic (1.95e-1)" "unprognostic (2.47e-1)" "unprognostic (4.20e-1)" "unprognostic (5.10e-3)" "unprognostic (1.76e-1)" "unprognostic (1.35e-1)" "unprognostic (7.06e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (5.43e-6)" "unprognostic (1.70e-2)" "unprognostic (1.07e-1)" "unprognostic (2.78e-3)" "unprognostic (6.11e-3)" 115.6 58.4 6.4 160.6 8.3 0.0 89.7 5.7 14.2 366.9 7.5 2657.3 136.3 1872.4 177.0 677.5 655.6 234.3 274.1 6.8 8.5 42.9 10.6 98.7 7.3 6.1 6.8 114.1 24.2 3.0 9.0 28.4 6.3 676.0 326.4 0.7 61.6 1585.7 21.8 57.8 431.3 2207.8 6.1 22.1 673.7 91.4 7.5 2.6 38.5 11.7 0.9 1386.6 305.7 6.3 0.1 1.3 5.9 1.0 0.6 0.2 3.2 91.5 34.9 48.0 64.6 27.9 0.0 0.4 2.7 26.1 4.4 0.3 0.0 0.0 71.2 0.0 0.2 0.1 0.1 2.3 2.5 0.0 0.4 3.0 0.1 28.7 0.1 1.6 0.0 0.0 35.8 0.0 0.0 0.0 0.3 3.8 2.9 0.0 0.7 0.2 0.6 3.8 0.0 0.0 0.1 1.3 0.1 0.2 0.2 72.5 0.1 0.1 0.4 0.4 34.6 1.2 1.2 0.1 0.4 0.1 3.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 6.4 8.3 5.7 14.2 6.8 8.5 6.1 6.8 6.3 6.1 7.5 6.3 2.4 0.0 0.0 0.0 0.2 4.8 4.1 1.6 0.6 0.0 4.2 191.0 51.4 0.0 0.3 1.8 0.0 0.8 0.7 0.0 0.0 14.5 335.0 3.1 20.7 2.4 0.0 0.0 0.5 0.4 1.0 21.5 0.5 0.7 0.0 0.5 6.8 0.0 2.3 0.0 0.3 0.0 0.0 0.0 9.4 554.6 8.4 0.9 3.6 2.8 0.6 0.5 0.0 0.0 0.1 0.9 0.0 221.2 0.0 4.0 0.0 0.4 0.4 0.0 39.5 1.1 180.9 8.3 19.5 0.4 7.1 0.7 1.1 0.7 0.0 1.1 CNN2 ENSG00000064666 "Calponin 2" Q99439 19 1026586-1039068 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 274.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049095 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA 8400000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 58: T-cells - T-cell receptor" Cytosol "Nucleoplasm, Actin filaments" "HPA049095: AB_2680627" "unprognostic (2.52e-2)" "unprognostic (2.69e-1)" "unprognostic (1.74e-1)" "unprognostic (4.49e-2)" "unprognostic (3.89e-1)" "unprognostic (5.31e-2)" "unprognostic (1.33e-1)" "unprognostic (2.56e-1)" "unprognostic (4.58e-2)" "unprognostic (6.56e-2)" "unprognostic (3.60e-2)" "unprognostic (3.33e-2)" "prognostic unfavorable (4.70e-7)" "unprognostic (1.28e-2)" "unprognostic (1.87e-1)" "unprognostic (2.50e-1)" "unprognostic (1.54e-1)" 76.7 22.1 6.3 149.8 7.9 208.8 82.1 9.0 11.2 88.2 30.3 64.1 25.6 118.0 20.0 131.7 88.7 78.8 60.2 6.1 6.7 65.0 42.9 152.2 184.2 9.5 7.7 164.7 69.2 8.6 22.4 37.8 9.6 84.1 33.6 7.5 89.4 68.4 8.1 76.5 64.8 56.0 7.9 154.0 75.1 12.1 9.0 52.2 79.0 7.7 169.9 86.4 79.7 13.3 230.7 75.6 206.9 257.3 104.5 196.9 162.6 204.3 221.8 249.2 192.5 263.0 191.8 151.2 203.9 367.9 58.9 221.3 123.9 324.1 164.7 104.7 10.6 109.6 122.0 205.9 415.0 97.4 230.1 337.2 150.9 158.1 118.5 405.6 142.9 110.1 64.0 225.2 206.0 44.0 8.9 91.5 256.2 184.0 35.0 52.8 72.5 170.9 247.5 265.9 0.5 14.8 252.6 34.3 27.5 149.6 247.6 163.6 349.4 134.8 140.0 210.0 208.9 105.2 86.8 297.8 79.6 117.7 220.9 560.2 142.2 631.5 243.1 180.6 393.5 231.0 301.6 324.2 217.5 201.9 250.1 252.0 845.4 213.8 209.4 96.7 347.3 393.3 6.3 7.9 9.0 11.2 6.1 6.7 9.5 7.7 9.6 7.9 9.0 13.3 10.3 60.9 60.6 0.0 140.4 97.6 274.2 142.9 178.2 1.2 36.5 66.4 6.1 15.7 78.4 36.8 10.4 12.0 66.4 47.0 62.6 63.6 0.5 29.1 52.9 26.3 15.4 44.1 0.1 138.6 99.8 50.4 49.5 40.0 59.5 44.3 37.9 29.8 54.9 0.0 0.1 51.2 42.7 87.9 103.1 1.8 8.1 90.7 14.2 2.8 129.9 0.9 91.6 0.0 0.6 186.9 27.1 76.8 85.8 60.9 3.3 5.9 37.8 7.5 32.9 10.4 70.6 1.7 3.8 135.0 87.8 11.4 160.8 1.7 32.1 170.9 CNTN3 "BIG-1, PANG" ENSG00000113805 "Contactin 3" Q9P232 3 74262568-74521140 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.1" "Group enriched" "Detected in many" 7 "Excitatory neurons: 274.0;Inhibitory neurons: 195.1;Oligodendrocyte precursor cells: 228.7" "Cancer enhanced" "Detected in many" "prostate cancer: 2.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BJ: 7.1;fHDF/TERT166: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003341 Approved "Intracellular and membrane" NA NA 130000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA003341: AB_1078556" "unprognostic (1.66e-2)" "unprognostic (1.86e-1)" "unprognostic (2.35e-3)" "unprognostic (9.86e-2)" "unprognostic (1.82e-2)" "unprognostic (1.94e-5)" "unprognostic (4.25e-2)" "unprognostic (2.13e-3)" "unprognostic (8.42e-2)" "unprognostic (3.85e-2)" "unprognostic (1.50e-1)" "unprognostic (7.25e-2)" "unprognostic (9.30e-7)" "unprognostic (4.23e-2)" "unprognostic (1.63e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-2)" 2.7 3.0 5.0 0.4 6.4 0.0 1.4 0.0 10.1 2.4 0.7 3.2 0.4 0.9 1.7 0.4 7.6 2.0 2.1 6.2 0.7 3.7 3.1 0.8 0.1 1.3 3.0 1.3 2.0 0.2 4.0 0.1 1.9 5.8 2.8 1.3 0.8 4.2 0.2 0.8 0.5 0.4 0.0 1.8 1.4 0.7 1.3 0.9 1.6 0.2 0.5 4.3 0.5 1.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 7.1 0.0 1.1 0.3 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 2.4 0.0 1.4 0.0 0.1 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 6.4 0.0 10.1 6.2 0.7 1.3 3.0 1.9 0.0 1.3 1.0 0.2 3.2 1.7 21.9 0.0 0.6 0.8 0.3 0.0 6.2 2.2 1.3 3.5 10.0 4.2 9.2 0.0 0.0 0.0 3.3 1.9 1.9 2.9 32.7 1.8 0.7 1.2 0.0 274.0 0.5 0.0 4.5 0.0 10.8 0.0 0.4 5.7 6.6 0.1 21.9 195.1 6.4 0.0 0.0 2.1 1.8 0.0 0.1 0.0 3.7 0.0 0.2 0.0 228.7 9.8 0.9 3.9 0.0 0.0 4.0 0.6 7.4 4.8 0.9 0.0 2.3 0.9 0.1 1.1 0.0 0.3 0.0 0.5 0.1 7.1 1.9 CNTNAP1 "Caspr, CNTNAP, NRXN4, p190" ENSG00000108797 "Contactin associated protein 1" P78357 17 42682531-42699993 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.7" "Cell type enhanced" "Detected in many" "Astrocytes: 11.4;Bipolar cells: 15.6;Endometrial stromal cells: 15.5;Excitatory neurons: 45.6;Inhibitory neurons: 37.7" "Cancer enhanced" "Detected in all" "glioma: 10.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 43.5;TIME: 68.5;U-138 MG: 76.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011772 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA011772: AB_1079541" "unprognostic (4.04e-2)" "unprognostic (3.69e-1)" "unprognostic (2.37e-3)" "unprognostic (1.89e-1)" "unprognostic (5.02e-3)" "unprognostic (1.13e-1)" "unprognostic (3.19e-3)" "unprognostic (1.19e-1)" "unprognostic (2.59e-1)" "unprognostic (9.76e-3)" "unprognostic (1.99e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.16e-14)" "unprognostic (9.52e-3)" "unprognostic (2.27e-2)" "unprognostic (3.11e-2)" "unprognostic (7.37e-3)" 7.1 3.6 27.5 5.6 30.8 0.6 5.0 13.5 46.7 12.0 0.0 23.8 1.8 21.8 6.1 2.2 14.0 6.3 8.2 29.5 15.7 6.4 1.5 6.9 2.4 21.6 15.4 15.7 11.5 0.6 19.3 4.5 19.1 7.2 3.9 11.3 2.9 6.5 3.7 2.2 6.0 25.9 8.1 4.9 9.8 3.3 18.8 1.2 4.9 2.5 2.4 8.0 8.5 29.4 4.1 5.4 13.2 4.2 20.0 40.4 0.8 25.6 43.5 18.2 16.5 0.5 1.0 0.1 1.3 27.7 18.6 4.8 6.4 2.0 14.2 9.0 2.1 0.0 24.0 6.4 9.8 0.2 0.4 39.7 0.1 17.5 3.5 29.1 23.3 0.2 1.2 7.6 7.1 0.7 0.1 3.8 4.7 0.3 5.5 0.7 1.4 2.0 4.8 0.0 2.4 7.7 7.6 0.1 4.7 12.0 4.1 2.3 68.5 76.2 12.5 18.0 7.0 8.5 5.7 0.2 21.4 1.7 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 27.5 30.8 13.5 46.7 29.5 15.7 21.6 15.4 19.1 8.1 18.8 29.4 1.0 0.0 4.1 11.4 0.5 0.5 0.2 0.4 1.2 15.6 0.2 0.1 1.3 0.0 0.7 0.0 4.2 0.0 0.1 0.1 0.0 0.0 0.9 3.2 15.5 1.2 0.0 0.0 45.6 0.0 0.0 4.2 0.5 1.0 0.0 0.1 1.8 0.0 0.1 1.7 37.7 0.1 0.0 0.0 0.8 0.3 1.5 0.2 0.0 6.5 0.8 0.9 0.0 7.5 5.2 0.1 0.1 0.7 0.4 0.3 0.0 0.1 1.6 3.0 6.6 1.1 6.3 1.4 1.1 0.3 0.3 0.3 0.6 0.2 0.1 0.2 COL10A1 ENSG00000123500 "Collagen type X alpha 1 chain" Q03692 6 116118909-116158747 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.5;choroid plexus: 39.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 26.6;Inhibitory neurons: 6.3;Microglial cells: 8.4;Oligodendrocytes: 27.9" "Cancer enhanced" "Detected in many" "breast cancer: 42.8;pancreatic cancer: 51.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTEC/SVTERT24-B: 39.7" "Low region specificity" "Detected in many" HPA053268 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA053268: " "unprognostic (3.83e-2)" "unprognostic (6.81e-2)" "unprognostic (7.20e-2)" "unprognostic (7.45e-3)" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (3.84e-2)" "unprognostic (1.49e-1)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" "unprognostic (4.37e-2)" "unprognostic (7.03e-2)" "unprognostic (1.38e-11)" "unprognostic (2.16e-3)" "unprognostic (7.22e-2)" "unprognostic (3.60e-1)" "unprognostic (2.06e-3)" 0.3 0.0 2.2 0.2 8.6 0.3 0.3 4.6 4.5 1.2 39.9 0.2 0.0 0.3 0.0 0.0 0.0 8.9 0.3 1.3 3.3 0.4 0.2 2.8 0.6 7.7 5.6 3.9 3.3 2.5 0.4 0.1 7.1 1.9 0.1 0.9 2.6 0.8 0.1 0.4 0.1 0.5 4.3 2.5 0.1 0.2 6.3 0.1 0.7 0.0 1.9 0.2 0.1 15.5 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.2 2.9 0.4 6.0 0.1 0.0 0.1 0.0 1.0 0.0 0.7 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.8 0.0 39.7 0.0 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.2 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.0 6.3 0.1 0.4 0.5 0.0 0.0 0.1 0.6 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 8.6 4.6 4.5 1.3 3.3 7.7 5.6 7.1 4.3 6.3 15.5 2.6 0.0 0.6 3.9 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.1 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.4 26.6 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 6.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.4 0.0 2.2 0.0 2.5 27.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.2 5.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 COL12A1 COL12A1L ENSG00000111799 "Collagen type XII alpha 1 chain" Q99715 6 75084326-75206267 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Endometrial stromal cells: 44.3;Excitatory neurons: 52.9;Fibroblasts: 99.7;Leydig cells: 60.3;Sertoli cells: 46.0;Smooth muscle cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "fHDF/TERT166: 1432.1;SiHa: 846.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 29.1" "HPA009143, HPA010021" Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 9100000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "HPA009143: AB_1847095, HPA010021: " "unprognostic (2.60e-2)" "unprognostic (2.80e-3)" "unprognostic (7.92e-2)" "unprognostic (8.27e-3)" "unprognostic (1.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (3.47e-3)" "unprognostic (1.38e-1)" "unprognostic (4.30e-1)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "prognostic unfavorable (1.69e-9)" "unprognostic (1.03e-3)" "unprognostic (1.81e-1)" "unprognostic (3.16e-3)" "unprognostic (1.92e-2)" 105.1 15.7 2.2 16.0 1.9 0.0 65.4 0.8 2.7 112.8 0.4 74.9 8.7 124.5 5.5 36.2 42.2 20.9 25.5 1.0 1.2 25.9 3.5 24.6 7.2 1.8 4.8 123.2 5.9 5.0 4.8 1.8 0.6 20.8 17.2 0.4 16.1 42.4 14.4 48.9 40.6 72.1 0.6 11.4 18.1 4.6 2.0 5.5 19.3 12.5 4.2 26.3 45.8 0.8 0.2 2.2 11.5 0.2 270.2 162.0 28.3 275.4 229.3 186.2 257.3 27.5 0.7 0.0 27.7 1432.1 3.9 59.2 0.5 28.7 174.6 0.2 1.4 0.2 101.1 0.1 97.9 0.3 0.2 234.9 5.0 42.2 50.6 173.6 32.0 0.1 0.0 0.0 29.4 0.2 0.1 0.2 6.4 0.0 15.3 0.1 23.1 0.2 8.9 14.4 0.0 0.0 846.1 21.2 0.3 15.5 131.8 0.5 0.2 78.5 97.0 41.5 91.4 0.1 0.1 0.4 26.4 0.3 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 0.8 2.7 1.0 1.2 1.8 4.8 0.6 0.6 2.0 0.8 14.2 76.9 5.1 2.3 0.0 20.6 0.6 12.7 5.2 0.4 4.7 7.1 4.1 0.0 4.7 3.7 0.0 0.6 0.0 0.0 0.0 1.4 24.1 6.3 44.3 11.0 0.0 0.0 52.9 4.6 1.3 99.7 2.6 14.1 1.3 0.1 3.3 0.0 0.8 0.0 32.4 0.0 0.0 0.3 18.4 14.7 60.3 1.8 21.4 38.4 0.0 0.0 0.0 19.6 1.2 6.7 0.0 13.2 0.1 1.7 0.0 0.9 1.7 0.0 46.0 20.0 48.6 0.3 0.6 0.6 13.1 0.7 2.5 1.4 0.1 0.3 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1831.7;gallbladder: 1378.0;smooth muscle: 1416.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 774.5;Fibroblasts: 2148.2;Glandular and luminal cells: 592.2;Leydig cells: 991.9;Peritubular cells: 501.0;Smooth muscle cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3899.2;ASC TERT1: 4637.0;BJ: 3995.6;BJ hTERT+: 2901.2;fHDF/TERT166: 13615.1;HSkMC: 4058.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 133.7" "CAB032650, HPA059738" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 27000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA059738: AB_2684116" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" 514.8 52.4 6.8 266.2 9.3 2.0 314.5 7.1 17.4 1831.7 18.1 175.7 61.1 411.2 61.6 263.2 206.6 1378.0 275.4 6.0 6.8 40.8 27.4 229.5 91.6 8.7 6.7 297.2 57.1 32.5 33.5 624.6 7.9 196.2 141.8 1.6 60.2 232.3 51.6 424.6 103.2 1416.9 8.8 69.3 89.1 136.6 15.6 32.8 86.4 102.1 60.1 805.6 295.2 8.2 0.1 0.0 22.8 1488.5 3899.2 4637.0 1.3 3995.6 2901.2 642.6 850.5 0.0 2.8 0.3 2.7 13615.1 0.0 0.6 2.2 1.5 160.9 0.1 0.2 0.1 0.0 0.0 1018.6 1.1 0.5 4058.4 0.1 507.9 2.4 0.3 0.5 0.0 0.3 0.3 551.0 0.0 0.6 1.5 2.5 0.0 6.3 0.5 0.8 0.8 0.1 0.0 12.9 1.4 0.3 1.0 0.1 296.0 2.1 0.1 15.9 1626.3 0.8 1022.7 115.5 1.2 0.1 0.4 408.6 0.5 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 9.3 7.1 17.4 6.0 6.8 8.7 6.7 7.9 8.8 15.6 8.2 112.9 3.2 12.9 1.0 0.8 223.1 0.7 9.3 4.6 0.2 7.2 8.6 21.7 0.0 3.3 1.8 0.0 31.5 2.5 0.0 0.0 3.0 8.4 183.2 774.5 57.2 0.0 0.0 0.0 0.2 31.7 2148.2 26.5 592.2 10.1 16.4 258.8 1.9 116.9 0.0 0.1 0.0 0.0 1.0 394.5 45.1 991.9 16.7 238.3 97.4 2.6 3.2 0.0 0.0 0.2 5.2 0.0 501.0 4.5 1.0 0.0 0.5 0.8 0.4 302.4 249.9 770.7 9.9 4.5 6.2 187.4 70.7 30.6 214.8 0.0 0.8 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 186.0;Excitatory neurons: 185.2;Fibroblasts: 145.7;Skeletal myocytes: 76.4;Smooth muscle cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 447.8;BJ hTERT+ SV40 Large T+ RasG12V: 382.4;fHDF/TERT166: 430.3;HSkMC: 340.2;SuSa: 373.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" 61.0 4.8 2.3 42.5 5.7 0.2 25.7 0.0 15.6 83.4 3.1 48.7 10.0 43.4 32.7 23.6 21.2 81.9 19.5 17.6 0.8 6.3 12.4 26.1 9.3 2.0 17.4 25.2 7.1 7.5 7.3 111.5 3.8 14.8 25.4 1.6 7.4 12.8 7.8 12.9 22.8 98.3 1.9 10.0 21.5 6.8 1.0 4.7 9.8 26.8 10.3 57.3 29.7 2.5 0.4 93.5 143.9 67.5 212.0 285.3 0.8 213.7 242.3 447.8 382.4 63.2 0.7 0.2 2.2 430.3 23.2 1.6 4.1 2.3 153.3 0.9 1.3 1.0 2.1 0.6 282.6 0.6 0.4 340.2 7.8 129.8 45.3 92.2 108.5 0.9 0.5 0.4 109.1 2.4 0.3 0.3 20.9 0.9 124.3 0.5 33.9 0.4 0.5 24.9 2.0 1.4 5.2 2.5 5.2 373.0 2.1 0.2 91.6 212.8 22.9 52.6 44.6 0.8 0.4 0.6 32.2 0.1 235.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 15.6 17.6 0.8 2.0 17.4 3.8 1.9 1.0 2.5 36.7 0.0 1.5 29.7 0.3 26.1 0.2 7.2 6.2 1.3 1.6 3.7 2.8 0.0 0.7 1.8 0.0 4.6 0.2 0.5 1.9 0.6 0.7 22.4 186.0 9.1 38.7 0.0 185.2 0.7 3.9 145.7 0.5 5.1 0.0 4.2 25.7 7.4 6.6 0.0 23.8 0.2 4.1 0.3 27.4 1.7 48.7 1.4 21.4 25.3 0.6 0.7 0.0 21.6 10.9 1.1 0.1 19.5 0.4 0.3 0.1 1.0 1.9 0.8 46.0 76.4 116.0 3.9 1.8 2.0 18.8 6.2 2.8 27.4 0.0 0.4 COL8A1 "C3orf7, MGC9568" ENSG00000144810 "Collagen type VIII alpha 1 chain" P27658 3 99638475-99799226 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Fibroblasts: 53.3;Hepatic stellate cells: 102.8;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 1098.3;hTERT-RPE1: 431.9;LHCN-M2: 313.0;TIME: 471.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053107 Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053107: AB_2682046" "unprognostic (3.13e-2)" "unprognostic (2.92e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-3)" "unprognostic (2.49e-1)" "unprognostic (2.31e-2)" "unprognostic (4.83e-2)" "unprognostic (2.62e-2)" "unprognostic (4.79e-2)" "unprognostic (3.58e-2)" "unprognostic (3.71e-1)" "prognostic unfavorable (9.39e-8)" "unprognostic (2.98e-3)" "unprognostic (1.72e-1)" "unprognostic (1.38e-2)" "unprognostic (1.32e-3)" 33.0 7.0 1.7 5.8 2.9 0.0 5.7 1.8 2.6 3.8 4.4 12.4 1.0 5.2 2.7 11.1 9.1 10.8 39.1 1.3 3.0 5.9 0.9 32.8 0.9 3.1 3.9 9.2 1.2 17.9 11.3 4.2 3.4 12.7 6.9 0.5 7.0 12.0 2.3 3.2 3.7 31.5 2.7 1.0 5.3 0.5 2.6 0.4 27.5 7.8 0.5 25.0 5.4 2.5 0.1 0.4 3.0 0.3 142.2 236.4 0.2 68.5 45.7 69.6 138.6 0.0 0.3 0.1 5.9 1098.3 1.9 0.1 0.4 88.2 157.8 0.1 0.2 0.1 7.9 0.0 26.8 0.0 0.1 142.8 3.2 52.6 82.9 431.9 129.4 0.0 0.1 0.2 313.0 0.0 0.0 0.0 2.6 0.0 0.9 0.0 0.0 0.0 144.3 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.1 0.2 471.5 31.0 24.1 1.6 34.2 0.1 0.0 0.1 58.4 0.0 241.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 1.8 2.6 1.3 3.0 3.1 3.9 3.4 2.7 2.6 2.5 4.4 246.8 22.1 0.0 0.4 0.8 0.5 2.8 14.8 0.4 1.8 5.2 4.9 4.3 3.9 9.2 0.0 0.1 0.9 0.0 0.0 0.1 1.3 0.2 2.6 14.1 0.0 0.0 1.9 0.0 0.3 53.3 2.0 0.3 5.1 0.2 102.8 0.8 0.1 0.0 0.7 0.0 0.0 1.9 2.3 1.0 2.1 0.8 1.8 4.7 0.2 0.7 2.1 9.0 0.6 0.1 0.0 9.4 0.5 0.2 0.0 1.6 1.0 0.6 0.0 1.9 51.6 0.3 0.3 1.0 0.6 0.4 0.9 0.1 0.0 0.5 COL8A2 "FECD, FECD1, PPCD, PPCD2" ENSG00000171812 "Collagen type VIII alpha 2 chain" P25067 1 36095239-36125222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 10.2;Cardiomyocytes: 13.5;Fibroblasts: 13.4;Macrophages: 6.8;Melanocytes: 7.2;Microglial cells: 8.4;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 5.8;fHDF/TERT166: 4.3;HHSteC: 14.1;hTERT-RPE1: 18.2;THP-1: 4.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.6" HPA049788 Uncertain Uncertain "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA049788: AB_2680882" "unprognostic (9.98e-2)" "unprognostic (3.26e-2)" "unprognostic (2.51e-2)" "unprognostic (8.41e-3)" "unprognostic (8.76e-2)" "prognostic favorable (9.44e-4)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (3.50e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.35e-5)" "unprognostic (1.08e-2)" "unprognostic (6.77e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-3)" 5.2 1.2 2.5 4.4 2.2 0.5 5.6 6.1 2.4 9.0 18.3 5.9 1.4 5.7 1.6 5.8 4.2 4.8 5.4 2.3 2.9 1.1 0.6 4.6 3.1 9.0 4.2 3.3 0.8 0.7 4.0 12.8 7.1 6.1 2.0 0.4 7.4 11.4 0.6 5.5 2.4 3.7 6.1 8.5 9.1 0.9 4.2 4.9 7.5 2.1 3.5 13.3 5.9 5.7 0.0 0.0 0.0 0.0 0.5 1.0 0.1 5.8 1.7 1.6 0.9 0.2 0.1 0.0 0.8 4.3 0.0 0.3 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.1 14.1 0.0 0.0 1.7 0.1 0.7 0.0 18.2 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.4 0.1 0.1 0.0 0.5 0.5 0.5 0.0 0.2 0.4 0.0 4.7 0.1 2.3 0.3 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.5 2.2 6.1 2.4 2.3 2.9 9.0 4.2 7.1 6.1 4.2 5.7 0.6 0.0 1.8 0.3 0.0 2.2 2.2 1.8 0.0 0.1 1.3 10.2 13.5 0.0 0.7 0.0 0.0 0.4 1.4 0.0 0.0 0.4 0.1 0.2 0.2 0.7 0.0 0.0 0.2 0.2 0.3 13.4 0.5 0.3 2.5 0.5 1.1 0.0 6.2 0.0 0.4 0.0 0.0 2.0 2.7 0.2 3.1 6.8 7.2 8.4 1.2 0.3 0.0 0.5 0.1 0.6 0.0 6.0 0.1 5.3 0.0 0.0 0.2 0.2 6.6 0.7 1.4 0.0 0.3 0.1 1.3 0.8 1.2 0.3 0.0 0.4 COMP "EDM1, EPD1, MED, PSACH, THBS5" ENSG00000105664 "Cartilage oligomeric matrix protein" P49747 19 18782773-18791305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cell adhesion" Heparin-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 77.6;heart muscle: 65.3;skin 1: 80.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 19.3;Early spermatids: 37.0;Fibroblasts: 32.0;Glandular and luminal cells: 32.0;Late spermatids: 75.3;Spermatocytes: 16.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 859.6" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA077555 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA077555: " "unprognostic (1.26e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (9.08e-5)" "prognostic unfavorable (2.04e-4)" "unprognostic (8.05e-2)" "unprognostic (8.45e-2)" "unprognostic (3.62e-2)" "unprognostic (5.12e-2)" "unprognostic (1.65e-1)" "unprognostic (1.55e-2)" "unprognostic (2.18e-2)" "unprognostic (3.85e-1)" "prognostic unfavorable (1.52e-6)" "unprognostic (5.96e-3)" "unprognostic (1.44e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (6.95e-4)" 77.6 0.2 0.0 1.1 0.2 0.0 11.0 1.3 0.2 7.5 0.0 2.3 0.0 4.6 7.6 9.5 1.2 16.1 65.3 0.0 0.0 5.2 0.3 8.0 3.6 0.3 0.1 0.4 2.8 2.2 0.4 8.2 0.1 10.2 0.0 0.0 14.1 6.7 18.0 80.6 0.9 12.1 0.3 0.3 2.5 14.9 0.0 0.1 10.3 0.6 0.3 6.5 22.7 0.1 0.0 0.0 0.0 0.0 178.4 0.4 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 859.6 0.0 0.2 1.2 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.3 0.0 0.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.2 0.0 0.0 0.3 0.1 0.1 0.3 0.0 0.1 0.1 3.2 0.5 0.0 0.0 11.5 0.6 19.3 0.0 1.4 0.3 0.3 0.8 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 37.0 2.8 3.7 1.0 0.0 0.0 0.1 0.2 0.2 32.0 0.0 32.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 1.3 0.0 0.0 10.7 75.3 0.9 0.7 10.6 0.0 0.1 1.6 0.0 0.0 0.1 0.2 0.0 0.7 0.0 0.3 0.0 0.0 0.7 0.4 6.6 2.4 4.2 16.8 1.6 0.0 7.1 0.5 1.0 0.0 0.2 0.3 COPA HEP-COP ENSG00000122218 "COPI coat complex subunit alpha" P53621 1 160288594-160343273 "Disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" Hormone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028024 Supported Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" NA NA 150000 "Cluster 18: Basophils - Vesicular transport" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA028024: AB_10603787" "unprognostic (1.59e-2)" "prognostic unfavorable (6.54e-4)" "unprognostic (2.77e-2)" "unprognostic (2.34e-2)" "unprognostic (3.54e-2)" "unprognostic (5.41e-3)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.42e-2)" "unprognostic (3.14e-1)" "unprognostic (2.21e-1)" "unprognostic (5.03e-2)" "unprognostic (3.10e-1)" "unprognostic (2.05e-2)" "unprognostic (8.70e-2)" "unprognostic (2.03e-1)" "unprognostic (4.94e-2)" "unprognostic (1.39e-1)" 47.7 43.1 46.6 38.5 48.9 30.0 42.0 57.2 57.1 52.9 67.4 42.3 53.7 46.7 55.1 38.3 41.2 38.6 55.1 48.6 53.7 48.6 55.0 47.0 36.1 57.9 51.0 46.9 49.9 51.8 59.8 48.3 60.0 43.5 47.9 26.2 57.6 39.4 59.1 40.0 49.0 50.0 53.9 42.7 43.5 24.4 51.1 37.6 60.1 38.2 38.9 41.3 37.9 66.4 91.0 68.5 70.1 66.9 164.9 154.7 78.6 116.5 144.3 103.1 138.7 72.0 60.5 64.4 73.3 194.0 57.7 86.0 92.0 81.3 126.5 68.6 64.3 76.8 95.2 79.0 115.1 94.1 74.5 134.8 49.1 140.0 128.9 126.3 126.4 64.4 71.9 69.7 124.4 43.6 49.3 53.3 80.1 97.3 79.0 49.2 89.2 118.9 94.3 94.7 62.1 84.3 157.3 109.2 148.0 115.0 140.4 133.9 162.8 84.3 54.1 108.2 80.2 106.8 76.3 106.6 104.2 51.3 122.8 48.1 39.0 25.4 18.6 36.7 25.5 17.8 16.7 21.3 40.4 14.2 14.3 17.9 10.9 26.7 36.2 17.8 22.9 35.5 46.6 48.9 57.2 57.1 48.6 53.7 57.9 51.0 60.0 53.9 51.1 66.4 53.6 76.9 54.7 44.7 66.4 28.2 35.5 41.6 29.6 52.4 53.0 41.3 51.8 42.9 49.7 40.5 81.3 41.0 83.2 66.8 13.7 49.9 14.7 50.7 68.1 50.4 55.3 37.0 77.6 49.6 63.3 66.2 65.2 64.3 45.6 63.0 52.8 71.1 51.2 45.4 73.8 83.8 30.5 93.7 58.0 6.4 71.1 84.3 26.6 67.5 75.0 41.0 38.1 65.9 178.9 55.5 48.1 56.8 115.9 52.9 98.9 41.4 66.2 53.7 39.5 57.6 52.4 37.6 25.7 35.8 31.8 69.2 58.3 58.1 66.6 61.2 COPB2 "beta'-COP, betaprime-COP" ENSG00000184432 "COPI coat complex subunit beta 2" P35606 3 139353946-139389736 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036867, HPA058180" Approved Approved "Endoplasmic reticulum,Golgi apparatus" NA NA 63000 "Cluster 18: Basophils - Vesicular transport" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "Golgi apparatus" "HPA036867: AB_10672271, HPA058180: AB_2683630" "unprognostic (3.37e-2)" "unprognostic (2.04e-1)" "unprognostic (9.38e-2)" "unprognostic (6.93e-2)" "unprognostic (1.31e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (2.41e-7)" "unprognostic (5.59e-2)" "unprognostic (2.14e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (8.11e-2)" "unprognostic (1.51e-2)" "unprognostic (6.44e-2)" "unprognostic (1.14e-1)" "unprognostic (6.05e-2)" "unprognostic (4.95e-2)" 46.7 58.2 17.9 50.5 19.7 22.3 60.4 20.4 21.0 76.5 35.9 62.5 57.4 48.5 62.5 55.0 47.5 48.4 47.9 17.4 21.8 52.9 71.1 44.3 44.8 20.5 18.9 38.9 89.7 68.2 60.0 68.9 20.4 72.2 71.7 37.0 71.1 57.0 33.5 37.4 53.4 63.5 20.8 42.8 60.7 35.0 20.2 54.4 64.3 31.2 61.5 56.2 42.2 25.0 192.1 84.0 111.2 99.0 247.2 214.9 96.8 223.9 235.9 158.2 204.7 143.4 83.5 90.2 203.0 287.1 145.1 110.9 136.2 141.0 210.6 139.0 85.2 138.2 114.9 152.3 152.7 121.9 139.7 160.1 114.7 132.2 138.5 178.6 161.6 76.5 86.7 105.7 199.4 138.6 59.4 59.7 102.2 215.0 99.5 75.8 93.6 149.5 141.2 133.4 85.2 61.7 254.6 212.0 147.2 168.6 193.2 123.2 185.1 90.3 66.4 122.8 83.7 148.0 80.8 129.7 115.2 61.0 138.0 74.4 49.8 52.0 36.0 56.3 35.8 35.3 31.0 37.6 57.7 23.8 24.2 31.1 45.0 44.1 57.2 30.2 38.1 44.2 17.9 19.7 20.4 21.0 17.4 21.8 20.5 18.9 20.4 20.8 20.2 25.0 36.6 57.7 46.6 18.3 45.8 19.6 39.5 61.2 29.6 38.0 41.3 29.3 58.5 32.9 74.5 20.2 31.3 83.3 34.9 52.4 41.1 83.4 40.8 64.9 62.9 45.2 63.9 51.1 25.1 82.1 76.1 66.6 75.4 54.8 45.0 50.4 36.4 48.5 52.7 42.1 25.5 86.7 46.8 34.6 21.3 8.6 54.7 42.8 21.4 13.1 60.1 62.0 29.9 20.1 30.8 79.7 34.8 50.0 118.6 46.6 46.9 42.4 108.6 51.1 19.7 47.3 69.6 83.1 45.6 36.5 14.9 133.1 37.5 74.4 44.7 52.9 COPZ2 MGC23008 ENSG00000005243 "COPI coat complex subunit zeta 2" Q9P299 17 48026167-48038030 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 49.8;Endometrial stromal cells: 63.8;Fibroblasts: 77.7;Leydig cells: 50.4;Smooth muscle cells: 49.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 167.4;ASC TERT1: 185.6;BJ: 127.1;BJ hTERT+: 133.1;fHDF/TERT166: 271.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055999 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA055999: AB_2683003" "unprognostic (2.66e-1)" "unprognostic (9.32e-2)" "unprognostic (2.18e-2)" "unprognostic (1.46e-1)" "unprognostic (6.28e-2)" "unprognostic (1.12e-1)" "unprognostic (2.77e-2)" "unprognostic (1.59e-1)" "unprognostic (9.34e-2)" "unprognostic (2.49e-1)" "unprognostic (7.02e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (3.45e-9)" "unprognostic (7.42e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (2.89e-6)" "prognostic unfavorable (4.66e-4)" 71.7 28.6 11.8 11.7 12.6 1.0 46.4 13.0 19.1 41.8 22.8 57.0 6.2 38.3 21.4 15.9 32.6 22.9 57.1 12.4 16.4 19.2 33.2 22.1 5.8 15.3 12.5 13.6 19.7 24.3 14.8 22.5 15.1 34.2 14.7 5.1 23.4 36.8 90.8 35.3 18.2 45.6 14.0 11.7 27.1 11.6 13.1 4.9 32.1 48.6 6.9 37.3 33.1 15.7 38.7 7.5 4.1 0.0 167.4 185.6 0.0 127.1 133.1 35.0 38.6 0.0 4.4 0.0 28.3 271.6 0.0 39.5 0.0 0.5 34.9 1.7 0.1 13.6 21.3 0.1 68.4 0.0 0.8 111.7 16.0 26.2 3.5 41.1 5.3 0.3 0.1 0.8 86.9 18.1 0.4 0.0 0.2 2.6 2.5 0.0 0.0 6.1 2.4 0.0 0.2 5.7 24.6 0.0 28.3 1.0 6.0 4.2 34.4 91.5 14.5 72.9 0.5 91.6 11.1 1.3 99.3 0.0 13.1 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.1 11.8 12.6 13.0 19.1 12.4 16.4 15.3 12.5 15.1 14.0 13.1 15.7 31.6 9.6 2.2 8.1 2.6 49.8 16.7 9.4 9.1 1.2 7.3 30.1 37.1 0.0 1.4 7.3 0.0 1.0 7.5 0.4 11.7 1.0 7.0 2.1 63.8 15.6 0.0 0.0 1.4 5.1 1.2 77.7 0.0 1.5 1.3 2.7 16.4 39.0 6.9 0.0 1.7 2.3 2.0 4.4 28.4 21.1 50.4 3.4 28.4 7.5 0.8 34.8 4.1 2.5 7.6 2.5 0.0 41.8 3.5 6.0 0.1 19.1 0.6 1.3 6.6 21.6 49.2 14.1 3.7 3.1 26.0 2.3 3.7 8.5 0.4 11.7 CORO1C "coronin-3, HCRNN4" ENSG00000110880 "Coronin 1C" Q9ULV4 12 108645109-108731526 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041737 Approved NA NA 13000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA041737: AB_10804115" "unprognostic (2.86e-1)" "unprognostic (2.82e-2)" "unprognostic (2.83e-1)" "unprognostic (3.96e-1)" "unprognostic (6.50e-3)" "unprognostic (1.32e-2)" "prognostic unfavorable (5.59e-5)" "unprognostic (2.49e-2)" "unprognostic (9.84e-2)" "unprognostic (2.41e-1)" "unprognostic (1.07e-2)" "unprognostic (3.96e-1)" "unprognostic (1.67e-3)" "unprognostic (2.93e-2)" "unprognostic (8.33e-2)" "unprognostic (3.39e-3)" "unprognostic (4.90e-3)" 68.5 30.6 36.1 49.7 36.1 52.5 36.6 28.1 36.8 49.9 22.1 116.6 28.9 96.1 24.1 67.7 55.9 54.4 33.7 41.3 39.1 25.8 49.1 76.4 31.6 43.9 37.1 30.4 13.0 36.4 22.0 48.2 39.0 35.8 53.3 10.5 24.6 67.3 30.0 52.1 42.9 142.9 38.3 26.1 45.0 22.5 40.8 47.4 14.2 23.6 33.6 71.5 44.7 53.4 188.2 207.2 274.3 140.8 137.3 186.5 117.3 347.8 372.0 443.2 353.6 245.8 81.5 10.6 88.8 547.9 173.2 85.4 153.3 255.1 558.1 82.8 71.4 313.8 95.3 192.7 123.8 76.6 154.1 173.7 120.3 501.0 376.9 262.3 234.1 51.8 157.0 101.0 473.6 68.4 34.7 90.5 70.5 68.7 197.9 53.3 158.6 121.9 176.0 122.5 75.0 66.3 115.6 16.0 156.6 173.0 83.0 58.0 263.7 316.1 165.1 297.7 296.8 99.4 245.7 232.8 246.3 64.0 215.5 42.3 70.7 32.0 7.4 78.1 3.5 24.6 2.9 4.5 75.7 19.1 1.0 3.3 81.9 12.6 75.2 75.9 7.5 44.7 36.1 36.1 28.1 36.8 41.3 39.1 43.9 37.1 39.0 38.3 40.8 53.4 24.5 54.5 20.7 18.3 27.8 138.0 168.2 47.7 66.0 7.1 18.2 14.1 19.0 18.6 34.6 12.9 2.1 28.4 39.1 41.3 3.9 59.7 58.9 33.6 47.2 51.9 30.9 25.5 32.8 22.7 125.3 38.4 20.4 39.1 41.8 43.3 17.2 49.8 122.2 15.2 39.7 23.4 16.2 71.0 181.4 56.4 22.4 108.8 90.7 37.5 81.7 6.7 8.2 46.3 42.6 76.9 29.8 58.6 31.6 92.8 19.0 30.1 10.5 5.3 13.1 42.8 53.2 26.8 22.9 60.6 167.8 46.8 12.0 9.9 30.7 93.2 CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 81.3;intestine: 75.4" "Cell type enhanced" "Detected in many" "Early spermatids: 106.8;Late spermatids: 202.5;Oligodendrocytes: 35.6;Peritubular cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "BJ: 18.4;fHDF/TERT166: 71.8;SuSa: 28.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" NA NA 62000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA048375: AB_2680377" "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" 29.1 6.4 3.9 5.9 7.2 0.0 20.8 9.2 2.6 5.8 81.3 75.4 6.2 10.2 59.8 18.4 16.0 11.2 18.0 3.5 7.2 11.2 2.4 7.0 2.7 16.1 10.7 16.7 5.2 2.5 10.9 1.2 11.6 15.1 7.0 0.5 9.3 12.7 3.8 7.3 14.9 56.9 20.0 16.8 19.9 9.6 10.4 7.8 15.0 7.9 6.6 28.3 9.2 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.4 0.7 1.1 0.1 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 28.0 0.5 0.0 0.0 0.1 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 7.2 9.2 2.6 3.5 7.2 16.1 10.7 11.6 20.0 10.4 18.3 22.3 0.0 0.6 0.3 0.1 2.2 0.0 0.2 6.2 0.0 0.3 0.4 2.4 0.0 0.0 1.8 0.0 8.3 0.1 0.2 1.9 0.4 106.8 0.2 0.2 26.1 0.0 0.0 5.0 0.2 0.3 23.0 1.1 0.3 0.0 0.1 16.8 0.0 0.3 1.7 0.5 0.7 0.0 0.0 2.7 202.5 10.8 0.6 3.6 0.0 0.0 0.0 0.0 1.0 35.6 0.1 0.1 79.0 1.4 0.0 0.4 0.0 0.0 0.1 0.0 1.6 2.0 1.3 1.9 0.6 2.0 5.1 0.2 0.0 2.7 0.2 CREB3 "Luman, LZIP, sLZIP" ENSG00000107175 "CAMP responsive element binding protein 3" O43889 9 35732598-35736999 "Predicted membrane proteins, Transcription factors" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 173.7;Late spermatids: 413.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030978 Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA030978: AB_2673683" "unprognostic (1.73e-3)" "unprognostic (9.72e-2)" "unprognostic (9.32e-2)" "unprognostic (5.62e-3)" "unprognostic (3.61e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (4.29e-2)" "unprognostic (4.63e-2)" "prognostic favorable (5.40e-4)" "unprognostic (1.13e-1)" "unprognostic (1.65e-1)" "prognostic favorable (3.77e-5)" "unprognostic (1.48e-1)" "unprognostic (1.61e-1)" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" 26.8 45.5 41.4 16.5 42.2 7.6 26.6 38.9 47.1 29.1 37.5 38.9 14.5 34.1 37.4 16.3 28.6 20.8 27.7 39.8 43.6 29.4 26.4 24.9 14.4 43.0 43.0 26.1 32.6 29.9 38.3 20.6 43.4 37.0 23.1 23.4 31.9 38.6 24.1 18.1 22.6 35.7 41.6 20.3 36.1 44.7 42.4 16.1 26.6 20.0 19.2 32.1 21.4 40.3 39.2 35.6 36.9 30.0 77.5 48.8 22.6 64.1 111.6 69.8 73.1 45.8 19.4 10.5 28.5 108.0 87.8 15.7 25.0 52.7 53.7 37.9 14.5 8.7 44.1 24.8 97.3 16.0 19.2 42.8 45.2 72.0 73.4 66.8 42.6 19.1 11.9 24.7 81.7 22.3 22.3 8.5 19.5 30.9 39.1 18.3 15.3 15.1 69.5 25.2 15.3 21.3 22.6 23.6 17.1 34.6 39.1 7.1 46.4 52.0 27.1 35.6 44.2 12.2 13.2 15.1 55.1 7.4 55.6 24.6 33.5 11.6 26.1 32.8 31.2 28.4 26.1 29.9 37.8 20.0 20.2 18.1 12.8 28.2 29.0 31.4 27.1 28.0 41.4 42.2 38.9 47.1 39.8 43.6 43.0 43.0 43.4 41.6 42.4 40.3 24.4 28.9 17.8 3.9 27.0 35.8 55.4 62.9 20.5 29.2 35.5 27.9 13.2 30.0 43.5 16.5 12.5 49.0 29.5 50.0 33.2 89.0 173.7 26.3 19.4 33.0 26.4 3.8 4.6 70.3 54.9 34.9 25.0 25.9 32.3 20.6 25.7 23.7 35.9 5.0 5.6 67.6 32.6 16.8 59.3 413.5 30.1 22.5 49.8 1.9 42.4 50.6 38.1 3.0 5.4 72.4 42.1 42.2 53.1 65.5 71.3 62.2 56.0 18.5 32.9 22.2 47.9 73.3 32.7 11.9 22.7 61.0 24.2 22.6 29.0 46.8 CREB3L1 OASIS ENSG00000157613 "CAMP responsive element binding protein 3 like 1" Q96BA8 11 46277662-46321409 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 133.9;salivary gland: 83.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 89.2;Gastric mucus-secreting cells: 105.0;Glandular and luminal cells: 120.5;Intestinal goblet cells: 280.5" "Cancer enhanced" "Detected in all" "prostate cancer: 87.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 134.3;BJ hTERT+: 130.7;BJ hTERT+ SV40 Large T+: 120.6;fHDF/TERT166: 321.8;OE19: 129.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA024069, CAB026151" Enhanced NA NA "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB026151: , HPA024069: AB_1854750" "unprognostic (2.46e-2)" "unprognostic (2.80e-1)" "unprognostic (1.34e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.66e-3)" "unprognostic (2.93e-1)" "unprognostic (5.41e-2)" "unprognostic (2.75e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (1.54e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.97e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (1.12e-2)" 8.6 15.1 4.3 8.0 3.3 0.1 10.7 0.9 4.2 43.2 2.1 41.2 27.7 20.4 2.4 3.2 5.2 25.0 15.6 7.2 3.4 2.8 1.1 14.8 0.7 1.9 5.1 9.3 133.9 2.3 10.7 26.7 4.1 42.3 43.3 0.1 83.0 26.8 4.4 5.6 30.6 13.3 1.1 3.2 68.0 3.9 8.4 1.0 4.5 4.2 4.7 21.4 15.3 2.4 0.9 0.8 1.3 26.1 81.9 77.9 0.6 134.3 130.7 120.6 83.3 13.7 0.3 0.0 0.7 321.8 8.3 0.0 1.6 0.4 66.6 0.1 1.5 2.0 0.8 0.0 113.5 0.0 1.9 75.2 0.0 68.6 2.5 109.0 1.0 0.5 11.2 0.0 102.5 0.0 0.1 0.4 17.0 129.0 13.7 0.1 18.0 0.2 0.2 0.0 0.0 0.2 0.9 3.4 0.2 23.3 0.1 4.9 0.0 62.7 18.3 48.6 83.4 0.1 0.1 0.0 75.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 3.3 0.9 4.2 7.2 3.4 1.9 5.1 4.1 1.1 8.4 2.4 10.3 0.0 46.4 0.3 0.6 1.5 44.4 2.6 0.0 0.0 52.0 5.1 15.9 25.8 10.0 29.5 0.0 1.2 0.1 56.8 3.9 42.0 2.1 37.2 24.1 9.0 9.1 0.0 2.1 89.2 2.3 49.4 105.0 120.5 4.5 1.9 3.3 0.0 1.9 0.0 1.0 280.5 6.1 0.0 3.5 6.6 83.6 1.0 10.6 2.8 2.0 0.0 0.0 19.6 0.1 49.2 59.8 44.4 0.2 40.4 9.5 0.7 3.6 0.0 0.0 0.7 29.3 1.0 1.5 0.6 2.3 3.4 1.8 10.7 57.7 51.3 CRIM1 S52 ENSG00000150938 "Cysteine rich transmembrane BMP regulator 1" Q9NZV1 2 36355778-36551135 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 163.8" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Hepatic stellate cells: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 466.5;fHDF/TERT166: 462.5;TIME: 651.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000556 Enhanced "Intracellular and membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA000556: AB_1078567" "unprognostic (2.15e-1)" "unprognostic (5.41e-2)" "unprognostic (6.39e-2)" "unprognostic (3.17e-3)" "unprognostic (3.88e-2)" "unprognostic (3.44e-2)" "unprognostic (1.88e-1)" "unprognostic (6.25e-2)" "unprognostic (2.32e-1)" "unprognostic (4.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.26e-1)" "prognostic favorable (9.51e-4)" "unprognostic (1.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (6.67e-2)" 88.3 14.6 27.0 18.8 28.1 3.5 58.9 9.4 23.5 26.7 51.4 28.7 14.9 26.6 16.7 30.5 34.4 32.2 34.5 20.3 28.8 70.0 16.0 50.1 14.8 23.5 21.9 36.9 23.5 29.2 7.4 163.8 21.2 25.8 23.2 29.5 31.1 32.6 50.1 27.2 18.2 35.7 22.1 47.1 17.5 12.4 36.1 9.9 33.8 36.5 8.7 38.9 22.2 17.1 100.9 75.4 15.2 17.5 69.1 78.0 125.0 466.5 244.7 255.4 133.4 95.3 34.2 0.2 297.9 462.5 166.1 42.8 11.4 75.2 206.5 1.1 8.7 3.2 96.7 55.5 221.5 2.2 0.6 110.1 55.2 102.4 182.4 238.4 361.9 1.9 4.7 0.7 271.6 9.2 0.2 1.2 11.9 5.2 22.1 5.4 19.6 15.5 159.8 41.1 1.8 0.2 81.5 26.4 3.4 56.2 72.3 2.0 651.1 321.7 116.1 40.4 229.1 25.5 0.5 0.9 94.7 0.4 100.8 1.4 0.1 0.5 0.6 0.0 0.4 0.3 0.2 0.3 0.1 0.2 0.0 0.3 0.2 0.4 0.6 2.1 0.2 0.0 27.0 28.1 9.4 23.5 20.3 28.8 23.5 21.9 21.2 22.1 36.1 17.1 262.9 12.8 43.3 100.2 5.4 66.0 38.5 30.1 43.9 12.0 55.6 72.9 34.4 47.1 26.5 132.4 2.1 111.9 27.1 49.5 3.9 33.5 1.0 37.1 27.7 159.8 31.8 10.7 85.1 2.6 40.6 41.0 10.2 75.9 1.3 27.4 207.1 3.6 27.7 0.0 57.5 37.7 36.7 7.7 32.5 2.0 19.0 8.2 39.2 135.9 7.1 18.5 6.2 65.9 17.2 26.5 30.9 19.9 6.9 75.5 11.5 38.4 28.9 42.5 46.0 18.4 164.6 2.1 9.4 22.0 30.1 173.5 17.1 5.7 33.2 58.3 CSF2 "GM-CSF, GMCSF" ENSG00000164400 "Colony stimulating factor 2" P04141 5 132073789-132076170 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lung: 2.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 11.4;Basal respiratory cells: 11.3;dendritic cells: 17.7;Ductal cells: 18.3;Pancreatic endocrine cells: 24.9;T-cells: 28.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "NK-cell: 6.2" "Lineage enriched" "Detected in single" 12 "NK-cells: 6.2" "Cell line enriched" "Detected in some" 4 "BJ hTERT+: 91.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA057404, HPA062006" Enhanced Vesicles "Secreted to blood" NA NA 23900 "Cluster 15: NK-cells - Transcription" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA057404: AB_2683428, HPA062006: AB_2684654" "unprognostic (7.29e-2)" "unprognostic (2.49e-3)" "unprognostic (8.77e-2)" "unprognostic (2.09e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" "unprognostic (2.56e-1)" "unprognostic (1.47e-2)" "unprognostic (2.64e-1)" "unprognostic (3.68e-3)" "unprognostic (1.87e-8)" "unprognostic (4.81e-2)" "unprognostic (1.22e-1)" "unprognostic (9.07e-2)" "unprognostic (2.06e-2)" 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 2.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 9.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 91.3 0.1 5.1 0.0 7.4 0.0 1.5 0.0 5.3 0.2 0.0 6.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 20.8 13.8 2.5 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.3 3.8 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.2 11.4 0.0 0.3 1.5 0.1 11.3 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 17.7 0.1 0.0 18.3 0.0 0.3 0.2 4.8 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.7 1.0 0.0 0.0 0.6 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.6 0.0 28.6 0.0 0.0 1.1 CSNK2B "Ckb1, Ckb2" ENSG00000204435 "Casein kinase 2 beta" P67870 6 31665227-31670343 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004349, HPA005944, CAB013087, CAB016059" Approved NA NA 83000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "CAB004349: AB_626791, CAB013087: AB_2533571, CAB016059: AB_626792, HPA005944: AB_1847290" "unprognostic (1.61e-1)" "unprognostic (3.21e-2)" "unprognostic (8.88e-2)" "unprognostic (1.55e-3)" "unprognostic (9.51e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-3)" "unprognostic (1.60e-1)" "unprognostic (7.52e-2)" "unprognostic (1.62e-3)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (5.88e-2)" "unprognostic (1.72e-1)" "unprognostic (9.67e-2)" "unprognostic (3.72e-2)" 155.8 157.4 15.8 31.9 24.6 62.2 150.2 17.6 54.1 147.9 16.8 142.2 27.8 126.7 183.7 166.6 130.1 33.1 178.9 15.9 16.4 172.1 163.7 133.0 72.5 16.3 17.5 161.2 142.3 69.3 130.0 68.2 17.8 120.3 50.4 41.4 131.9 57.6 232.0 294.2 126.5 66.3 15.4 146.0 146.7 257.9 17.1 56.5 132.4 94.8 30.1 126.2 139.8 17.4 0.9 95.5 2.5 164.9 97.4 158.0 120.8 200.9 350.2 407.6 377.9 0.2 129.3 302.5 127.9 196.8 146.0 0.1 1.0 374.5 409.4 153.1 322.6 4.3 0.6 1.1 260.0 341.5 0.9 257.8 1.5 0.8 0.2 0.2 4.7 208.3 1.7 1.7 0.8 2.9 237.1 2.2 102.0 240.0 0.0 221.1 2.3 247.7 222.3 136.5 1.2 243.0 1.8 0.9 175.8 101.0 7.4 1.3 118.8 210.3 203.9 198.0 1.3 167.3 285.9 267.6 122.3 1.6 196.1 87.3 114.8 121.8 80.1 125.9 80.5 113.7 81.7 85.1 111.0 99.1 71.4 61.9 95.2 90.8 83.2 131.7 113.4 95.0 15.8 24.6 17.6 54.1 15.9 16.4 16.3 17.5 17.8 15.4 17.1 17.4 114.3 51.3 67.0 11.1 124.4 186.1 125.1 196.1 138.9 56.8 135.5 196.3 91.3 105.8 116.5 101.2 12.5 211.8 106.4 185.6 270.1 184.7 452.7 75.1 71.7 122.7 125.7 103.5 14.1 175.2 252.7 118.3 93.3 68.2 129.5 102.3 125.7 126.6 296.2 48.8 14.3 175.4 138.4 204.4 218.5 270.7 153.7 146.2 152.9 8.4 181.1 168.3 121.5 14.6 19.1 182.9 248.1 125.3 152.1 154.3 283.1 397.5 91.3 47.8 138.1 107.9 152.2 485.6 186.5 142.7 186.3 282.1 111.5 116.8 184.3 150.6 CSRP1 "CSRP, CYRP, D1S181E" ENSG00000159176 "Cysteine and glycine rich protein 1" P21291 1 201483530-201509456 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 2743.3;seminal vesicle: 2571.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 341.2;Breast myoepithelial cells: 737.5;Extravillous trophoblasts: 388.5;Smooth muscle cells: 419.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045617 Uncertain NA NA 11000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA045617: AB_2679391" "unprognostic (7.08e-2)" "unprognostic (1.59e-2)" "unprognostic (4.86e-2)" "unprognostic (9.89e-3)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.61e-4)" "unprognostic (2.87e-1)" "unprognostic (1.45e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (9.24e-2)" "unprognostic (2.58e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.96e-3)" 344.5 127.2 713.6 224.5 871.4 41.0 321.8 742.5 717.3 542.4 467.6 2743.3 180.6 1904.4 308.4 884.1 1025.6 152.7 194.2 647.3 735.1 192.5 114.7 386.0 64.9 840.1 837.4 319.0 114.6 188.0 117.0 118.3 719.0 947.2 432.0 24.2 250.1 2571.3 64.0 219.8 503.6 2009.6 713.5 165.6 748.3 44.2 848.5 48.0 186.4 53.8 65.7 1494.5 469.1 766.6 83.0 195.3 52.0 116.4 83.2 107.7 273.6 605.7 514.3 455.3 360.9 211.1 57.7 78.7 36.1 325.0 96.7 144.7 32.7 120.3 321.2 169.5 29.3 90.7 220.1 30.7 387.4 72.1 10.2 99.3 105.3 373.0 163.1 253.1 508.1 34.9 4.5 71.9 302.1 232.9 46.6 11.8 0.8 99.0 73.2 18.3 304.9 266.8 212.6 129.7 27.1 22.5 238.0 503.8 163.9 25.6 87.0 74.3 610.6 303.7 195.7 206.6 250.6 40.5 82.6 30.6 303.5 137.6 202.6 75.5 49.8 65.6 37.4 49.3 36.9 25.0 35.8 34.9 65.0 18.1 20.5 25.2 5.0 34.3 54.2 5.2 54.1 46.5 713.6 871.4 742.5 717.3 647.3 735.1 840.1 837.4 719.0 713.5 848.5 766.6 151.8 38.5 47.8 86.5 21.8 49.2 341.2 24.6 207.7 3.4 123.7 737.5 24.8 21.5 36.9 47.8 0.0 88.8 23.3 96.6 49.0 165.1 21.5 30.1 73.6 86.9 57.9 19.1 2.4 171.7 388.5 86.7 36.7 38.9 27.9 13.9 91.1 28.3 66.0 0.0 2.1 80.0 14.2 29.1 55.8 44.9 41.0 37.0 126.3 10.3 73.5 137.4 15.5 6.6 114.8 140.5 71.4 292.3 61.5 113.8 97.2 28.4 25.2 3.1 144.7 37.7 419.9 2.4 3.2 75.3 34.9 160.9 31.2 30.4 69.7 103.6 CTIF KIAA0427 ENSG00000134030 "Cap binding complex dependent translation initiation factor" O43310 18 48539031-48863217 "Predicted intracellular proteins, Transporters" "Nonsense-mediated mRNA decay, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 94.7;Excitatory neurons: 76.4;Inhibitory neurons: 80.6;Oligodendrocyte precursor cells: 75.9;Oligodendrocytes: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016865, HPA024801" Uncertain Supported Cytosol NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "HPA016865: AB_1852311, HPA024801: AB_1852312" "unprognostic (5.84e-2)" "unprognostic (5.86e-2)" "unprognostic (2.27e-2)" "unprognostic (1.23e-2)" "unprognostic (2.06e-1)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (8.86e-2)" "unprognostic (1.95e-3)" "unprognostic (2.77e-3)" "unprognostic (1.35e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.95e-1)" "unprognostic (1.99e-1)" "unprognostic (2.34e-3)" "unprognostic (7.33e-3)" 35.3 20.0 15.7 3.3 13.9 2.0 24.3 10.7 23.2 14.0 0.0 26.0 2.5 21.5 2.6 11.4 16.3 7.5 24.8 16.0 15.5 11.1 24.8 14.3 1.3 20.7 17.4 28.0 9.8 4.6 12.4 4.3 23.3 13.9 1.6 7.4 11.0 5.4 15.8 14.0 9.9 7.0 9.1 6.7 19.6 7.3 19.0 1.4 10.7 4.3 1.0 26.1 12.6 16.7 3.2 3.4 4.5 5.8 11.3 6.0 2.5 15.9 13.2 12.4 11.2 3.5 1.9 0.0 3.5 22.0 5.2 6.7 3.3 9.0 5.3 0.0 2.7 1.4 7.9 8.4 21.6 2.6 4.5 8.4 14.5 7.8 13.8 8.9 8.9 4.1 4.0 9.8 8.0 1.7 0.9 2.0 2.2 3.4 2.8 1.6 5.2 4.2 3.7 4.3 9.6 9.7 5.6 6.0 4.5 3.8 3.8 3.1 18.1 11.4 10.5 3.4 2.9 3.3 4.2 0.0 10.1 1.6 5.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 13.9 10.7 23.2 16.0 15.5 20.7 17.4 23.3 9.1 19.0 16.7 7.3 35.3 3.7 94.7 1.9 3.3 2.1 3.5 2.8 25.6 11.2 8.4 16.0 5.7 5.6 7.3 16.7 1.9 0.8 4.6 7.9 5.1 11.1 1.7 7.7 8.5 3.5 0.4 76.4 4.8 2.8 13.1 7.1 3.6 4.5 19.5 7.5 23.0 4.2 11.8 80.6 3.5 4.1 6.4 2.7 19.3 25.1 5.0 3.6 30.0 1.5 3.6 3.1 75.9 59.7 5.7 2.7 50.8 4.8 3.0 5.9 5.8 4.7 8.8 6.6 8.8 9.4 2.3 1.8 3.5 2.3 1.2 0.7 34.7 3.3 3.3 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88265069-88359684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 900.7;Club cells: 471.8;Hofbauer cells: 1100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" No No 19000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB025364: , HPA066610: AB_2685694, HPA068434: AB_2685989" "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (9.30e-5)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-2)" "unprognostic (3.35e-1)" "prognostic favorable (4.80e-4)" "unprognostic (2.93e-1)" "unprognostic (4.35e-2)" "unprognostic (8.10e-2)" "unprognostic (4.07e-2)" 173.2 60.7 9.9 185.1 9.6 71.7 63.4 11.1 24.9 77.9 14.2 143.1 121.0 43.9 28.5 63.3 54.0 182.0 38.5 9.5 10.1 234.7 82.0 272.6 243.7 14.0 11.9 22.1 52.2 42.4 39.3 253.3 13.3 26.0 191.5 3.7 131.6 28.9 18.8 29.6 128.8 88.9 11.5 197.2 73.6 22.8 19.5 63.7 43.6 31.9 140.6 176.3 43.3 21.3 80.3 75.9 27.6 69.9 103.7 286.1 218.4 626.5 1078.4 372.8 270.3 194.7 361.3 117.3 278.9 365.2 84.3 133.6 50.4 269.2 341.9 204.7 82.8 144.5 188.0 233.5 140.2 188.9 108.7 419.1 198.8 284.5 697.4 302.1 377.6 122.3 155.3 145.4 54.8 14.8 89.1 295.1 172.2 551.5 244.9 113.6 30.7 227.0 451.3 106.6 8.8 66.8 81.2 114.9 80.6 185.4 27.9 152.7 149.3 23.5 190.5 156.8 364.6 61.9 81.0 122.9 56.8 435.8 122.4 85.5 203.8 309.7 230.1 415.6 194.9 47.2 99.6 198.2 209.9 26.3 49.5 115.3 215.0 200.5 582.9 425.0 162.7 243.3 9.9 9.6 11.1 24.9 9.5 10.1 14.0 11.9 13.3 11.5 19.5 21.3 78.6 22.4 88.1 0.3 40.8 30.1 7.3 900.7 33.6 1.5 15.9 14.6 4.4 52.9 471.8 40.5 0.0 414.1 330.6 37.9 29.4 29.8 1.6 13.4 135.6 94.8 11.4 29.7 3.0 90.6 159.2 114.4 39.8 21.2 75.3 25.5 26.4 15.8 1100.6 0.0 8.2 19.4 158.7 344.7 200.7 7.9 198.5 391.7 48.0 61.8 185.4 0.5 299.7 13.6 0.4 44.8 72.3 25.6 78.5 8.5 20.2 166.4 93.7 0.8 59.2 4.4 150.8 3.0 11.1 43.3 27.1 227.3 170.6 286.7 44.9 16.1 CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58985686-59008238 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1078.9;Langerhans cells: 983.5;Macrophages: 652.3;monocytes: 723.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 542.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "CAB025114: , HPA049876: AB_2680927, HPA053504: AB_2682172" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" 178.1 117.8 18.9 208.8 21.8 99.8 137.0 20.5 32.0 92.1 59.6 173.8 215.4 87.3 13.4 53.1 88.9 89.4 152.6 15.3 33.9 125.6 356.4 233.3 271.5 31.6 23.5 71.0 89.4 91.8 112.5 118.7 27.9 87.8 77.1 4.1 181.0 66.3 58.7 58.5 226.0 97.9 26.2 234.4 88.2 24.6 47.2 57.1 122.3 54.6 91.3 146.3 69.0 45.4 205.4 139.8 1.1 1.1 114.2 124.2 106.5 291.0 225.4 187.4 152.3 231.6 324.6 96.5 213.9 542.1 0.5 160.1 51.4 257.5 30.2 362.1 13.6 80.3 169.0 0.8 137.3 9.0 331.0 130.9 127.8 83.1 62.4 34.8 281.3 1.1 74.0 48.7 90.0 1.1 1.3 70.6 11.5 43.5 158.2 2.9 0.4 135.7 86.3 25.5 2.7 1.7 222.4 258.4 0.8 19.5 131.9 148.4 420.5 1.4 161.8 209.0 2.0 253.7 172.0 18.2 2.8 207.9 0.4 1.2 1.5 1.6 0.6 1.4 0.4 1.1 0.6 0.4 1.1 1.4 0.7 0.8 1.6 0.5 2.9 1.8 0.3 0.7 18.9 21.8 20.5 32.0 15.3 33.9 31.6 23.5 27.9 26.2 47.2 45.4 132.1 16.0 5.3 5.9 119.8 50.3 64.5 33.8 24.5 6.7 67.4 99.6 21.7 62.9 14.1 71.7 0.0 38.2 104.8 303.6 23.5 176.0 3.5 52.9 47.7 82.2 27.1 63.3 5.3 42.4 104.8 71.5 19.4 71.3 10.8 68.4 62.8 363.0 1078.9 11.8 3.0 56.6 26.4 334.0 983.5 6.0 13.1 652.3 101.4 23.4 723.6 58.6 21.6 2.5 2.5 82.6 217.5 13.9 96.3 50.6 339.8 90.0 18.8 5.0 46.0 67.5 74.5 3.7 4.8 14.5 41.5 41.3 33.4 3.3 99.7 52.7 CUL4B ENSG00000158290 "Cullin 4B" Q13620 X 120505920-120604074 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Ubl conjugation pathway" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 106.9;Late spermatids: 169.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003046, HPA011880, CAB017786, HPA058979" Enhanced Enhanced Nucleoplasm NA NA 18000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "CAB017786: , HPA003046: , HPA011880: AB_1847340, HPA058979: AB_2683868" "unprognostic (2.34e-2)" "unprognostic (2.74e-2)" "unprognostic (2.69e-2)" "unprognostic (7.73e-3)" "unprognostic (9.66e-2)" "unprognostic (3.91e-1)" "unprognostic (3.88e-3)" "unprognostic (8.99e-2)" "unprognostic (8.12e-3)" "unprognostic (3.20e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-1)" "unprognostic (2.87e-3)" "unprognostic (3.83e-2)" "unprognostic (1.35e-1)" "unprognostic (6.82e-2)" "unprognostic (2.84e-1)" 18.7 20.5 15.3 14.4 16.5 9.8 20.0 18.2 19.3 24.6 15.7 20.0 12.3 18.7 27.3 23.4 19.6 15.5 15.5 16.0 19.2 18.1 19.5 14.5 20.5 14.4 16.4 25.2 17.0 24.2 26.9 15.5 15.7 18.2 13.5 19.9 15.1 22.5 10.0 15.2 15.4 15.6 13.7 17.7 15.5 28.0 16.2 25.3 15.8 12.5 21.8 18.2 20.3 16.1 41.9 37.3 28.7 31.4 129.5 57.0 22.4 89.8 104.1 71.3 69.4 30.4 110.6 40.1 35.5 206.8 127.7 29.9 61.1 27.7 84.8 26.1 26.6 20.5 42.1 25.9 50.6 22.6 28.1 65.6 22.2 45.1 37.5 134.8 133.2 22.6 33.6 31.7 78.4 24.5 30.7 19.0 45.4 52.6 39.5 23.4 27.1 43.4 23.2 19.5 32.9 27.4 74.2 36.8 36.5 35.0 28.8 20.9 177.6 57.1 30.5 76.3 88.6 21.2 50.0 52.2 59.9 28.2 55.2 6.6 3.8 8.1 5.6 3.1 6.1 5.7 5.2 5.2 4.4 4.4 6.0 6.2 14.4 4.4 2.4 7.0 6.9 4.1 15.3 16.5 18.2 19.3 16.0 19.2 14.4 16.4 15.7 13.7 16.2 16.1 18.7 22.4 14.4 11.8 15.5 15.2 9.6 12.9 12.5 15.7 17.3 14.7 14.6 8.6 11.7 14.7 14.6 10.1 19.9 14.7 13.7 10.1 106.9 12.4 15.6 18.2 24.6 13.3 18.4 8.9 25.0 21.2 14.3 15.8 14.0 20.5 40.7 16.4 17.5 25.2 20.9 13.9 8.2 30.5 13.9 169.3 21.5 18.4 12.4 14.0 17.6 15.0 7.2 23.1 21.0 16.7 7.3 21.4 18.9 9.5 11.0 14.4 17.8 14.1 13.1 17.0 16.6 12.6 13.9 23.0 13.8 10.0 14.1 21.7 12.7 9.5 CXCL8 "3-10C, AMCF-I, b-ENAP, GCP-1, GCP1, IL-8, IL8, K60, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8, TSG-1" ENSG00000169429 "C-X-C motif chemokine ligand 8" P10145 4 73740541-73743716 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 3301.3" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13262.1;Macrophages: 3685.4;Prostatic glandular cells: 8869.1;Urothelial cells: 13149.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 9 "cerebral cortex: 136.1" "Immune cell enriched" "Detected in some" 451 "neutrophil: 483.0" "Lineage enriched" "Detected in single" 788 "granulocytes: 483.0" "Group enriched" "Detected in many" 5 "BJ hTERT+: 4072.6;GAMG: 1080.2" "Not detected" "Not detected" HPA057179 Supported Approved "Golgi apparatus" "Secreted to blood" NA NA 7260 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA057179: AB_2683362" "unprognostic (3.42e-1)" "prognostic unfavorable (1.18e-5)" "unprognostic (3.91e-3)" "unprognostic (8.49e-2)" "unprognostic (3.29e-2)" "unprognostic (3.03e-3)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.37e-3)" "unprognostic (3.19e-1)" "unprognostic (4.46e-1)" "unprognostic (7.19e-3)" "unprognostic (7.16e-2)" "prognostic unfavorable (3.13e-6)" "unprognostic (4.73e-2)" "unprognostic (8.57e-2)" "unprognostic (1.64e-2)" "unprognostic (6.15e-2)" 67.9 13.5 1.8 209.9 2.8 3301.3 3.6 1.7 136.1 54.5 7.6 10.6 3.6 41.0 0.2 3.7 8.9 177.2 33.8 1.7 1.6 10.8 77.7 91.2 1.2 2.1 1.6 6.0 16.1 1.8 3.2 41.1 15.1 9.6 7.3 0.9 25.4 1.5 1.3 3.2 4.9 12.7 1.9 10.3 8.8 0.7 4.9 15.2 3.4 8.1 8.7 456.7 4.0 1.9 2.7 1.4 0.0 0.1 3.9 19.4 0.2 25.7 4072.6 35.9 117.0 0.2 13.0 0.2 547.6 1.3 1080.2 48.2 0.0 1.0 562.3 1.8 0.2 0.9 0.4 6.5 6.8 41.0 2.5 12.4 1.7 119.0 2.9 12.9 124.9 0.0 1.4 0.8 0.7 0.0 0.0 55.7 0.0 14.7 20.3 0.3 0.5 0.9 317.3 17.2 0.1 0.0 1.9 0.1 61.1 0.8 0.1 5.6 308.3 56.8 5.1 15.1 55.0 0.4 0.7 1.7 252.5 30.9 88.2 1.0 0.6 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 483.0 0.0 0.0 0.0 0.0 0.1 1.8 2.8 1.7 136.1 1.7 1.6 2.1 1.6 15.1 1.9 4.9 1.9 28.6 51.3 254.1 0.0 26.4 0.0 13262.1 0.0 164.4 0.5 40.2 15.4 23.8 127.2 426.5 0.0 0.0 4.3 17.7 14.4 0.0 1695.0 3.2 717.6 257.1 712.2 19.1 8.0 0.0 260.7 5.2 1475.1 54.0 1708.7 51.2 0.5 15.7 3.6 367.1 0.0 0.0 26.4 0.0 543.0 0.0 1.9 0.6 3685.4 0.0 0.0 1178.5 0.5 0.0 0.0 0.0 584.9 0.3 0.4 27.3 8869.1 0.9 1.0 178.6 1.1 39.5 44.3 263.0 0.3 2.5 124.9 0.0 21.3 138.8 0.0 18.5 13149.4 CYB5R2 ENSG00000166394 "Cytochrome b5 reductase 2" Q6BCY4 11 7665100-7677222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 139.2;testis: 133.6" "Cell type enhanced" "Detected in many" "Early spermatids: 268.0;Late spermatids: 601.1;Spermatocytes: 115.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 6.1;memory B-cell: 10.6;naive B-cell: 2.8" "Group enriched" "Detected in many" 9 "B-cells: 10.6;granulocytes: 6.1" "Cell line enhanced" "Detected in many" "BJ hTERT+: 125.1;BJ hTERT+ SV40 Large T+: 65.9;BJ hTERT+ SV40 Large T+ RasG12V: 59.4;HBF TERT88: 52.0;NTERA-2: 69.8;WM-115: 96.3" "Low region specificity" "Detected in single" "HPA038962, HPA061707" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" Nucleoplasm "HPA038962: AB_10675954, HPA061707: AB_2732668" "unprognostic (1.47e-1)" "unprognostic (2.56e-2)" "unprognostic (8.90e-3)" "unprognostic (4.41e-2)" "unprognostic (4.13e-3)" "unprognostic (1.60e-2)" "unprognostic (4.02e-2)" "unprognostic (2.48e-1)" "unprognostic (3.41e-2)" "unprognostic (1.30e-2)" "unprognostic (2.64e-3)" "unprognostic (1.10e-1)" "unprognostic (4.78e-2)" "unprognostic (1.40e-1)" "unprognostic (8.16e-2)" "unprognostic (1.70e-1)" "unprognostic (7.01e-2)" 8.8 3.6 17.2 5.7 23.1 4.1 15.6 18.7 25.3 15.6 13.2 4.6 2.4 22.8 25.5 19.6 10.1 6.8 4.7 18.2 19.7 5.9 5.1 11.5 2.7 19.5 22.5 29.3 4.3 29.0 1.3 13.8 19.2 19.5 5.3 139.2 35.7 22.3 1.7 51.1 4.3 13.2 16.9 3.0 5.6 133.6 21.8 0.9 5.1 1.7 10.5 13.3 17.7 28.0 7.1 3.6 1.5 0.0 0.3 1.7 22.8 43.9 125.1 65.9 59.4 0.7 9.4 0.2 10.3 22.7 20.2 0.8 0.1 0.3 52.0 0.1 0.2 0.0 3.8 0.9 35.0 0.4 6.6 17.7 1.4 0.3 3.7 0.1 5.6 0.0 6.9 0.1 0.5 0.0 0.0 0.1 69.8 7.4 3.4 34.1 0.1 0.0 0.0 4.4 0.0 0.7 0.3 28.0 1.9 11.1 4.8 9.4 0.0 6.1 0.1 0.3 3.4 0.2 0.0 10.7 0.5 0.0 96.3 0.0 0.9 6.1 0.0 0.5 0.0 10.6 0.1 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.6 17.2 23.1 18.7 25.3 18.2 19.7 19.5 22.5 19.2 16.9 21.8 28.0 0.6 22.4 5.1 0.0 2.3 7.0 8.4 12.3 8.6 1.3 8.8 12.8 3.0 1.5 6.3 3.7 20.9 5.3 0.1 0.6 0.0 1.4 268.0 5.5 11.2 1.7 0.0 0.0 0.0 4.7 20.0 8.1 1.5 14.3 2.5 0.5 0.4 1.8 2.5 0.0 0.1 1.8 6.1 0.0 0.5 601.1 4.7 1.5 5.4 1.9 0.5 0.8 0.0 0.5 8.5 6.0 1.4 6.0 2.9 11.2 0.3 0.4 10.2 35.2 13.1 2.3 7.5 115.6 9.8 12.8 10.1 4.5 0.2 1.8 1.8 11.4 DAB2 DOC-2 ENSG00000153071 "DAB adaptor protein 2" P98082 5 39371675-39462300 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Endocytosis, Protein transport, Transport, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 179.1;placenta: 226.6" "Group enriched" "Detected in many" 5 "Hofbauer cells: 1756.4;Proximal tubular cells: 1653.7;Syncytiotrophoblasts: 1324.5" "Cancer enhanced" "Detected in all" "renal cancer: 52.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "plasmacytoid DC: 48.7" "Lineage enriched" "Detected in many" 8 "dendritic cells: 48.7" "Cell line enhanced" "Detected in many" "ASC diff: 220.1;ASC TERT1: 234.5;fHDF/TERT166: 356.8;TIME: 211.1;U-138 MG: 237.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009314, HPA028888" Enhanced Enhanced "Nucleoli fibrillar center,Vesicles,Plasma membrane" NA NA 130000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "Nucleoli fibrillar center" "CAB009314: AB_638976, HPA028888: AB_2672814" "unprognostic (1.24e-1)" "unprognostic (7.28e-2)" "unprognostic (2.16e-1)" "unprognostic (1.25e-1)" "unprognostic (5.37e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (7.38e-6)" "unprognostic (3.11e-1)" "unprognostic (2.82e-1)" "unprognostic (2.78e-2)" "unprognostic (1.50e-1)" "unprognostic (1.87e-1)" "unprognostic (3.16e-2)" "prognostic unfavorable (9.67e-4)" "unprognostic (1.27e-2)" "unprognostic (2.24e-1)" "unprognostic (1.20e-1)" 76.9 113.6 7.3 33.1 8.3 4.1 48.2 13.4 13.1 48.4 26.2 33.2 13.5 32.5 116.8 16.8 21.6 50.1 20.0 7.5 7.7 179.1 27.3 53.3 33.2 14.6 10.0 34.0 22.8 10.1 7.9 226.6 12.6 13.0 54.5 11.6 24.2 19.8 11.4 21.2 25.6 47.8 7.8 58.5 16.6 10.6 20.1 20.9 23.5 16.4 19.0 44.6 20.6 10.8 0.2 8.3 12.9 27.9 220.1 234.5 16.0 145.7 149.5 56.3 92.5 108.1 0.5 0.1 8.8 356.8 54.8 0.3 2.0 5.2 78.9 0.2 4.2 19.9 191.1 35.5 52.4 0.2 24.3 146.5 0.2 91.7 16.5 87.2 172.4 9.9 0.0 5.0 95.2 0.6 2.1 0.3 8.9 4.1 15.8 5.4 32.7 0.0 37.8 3.2 0.1 0.4 17.4 9.3 79.2 20.4 0.6 4.9 211.1 237.9 26.1 27.7 11.9 0.2 0.1 0.3 82.6 18.1 31.5 5.8 2.3 0.5 2.1 4.6 0.1 0.1 0.3 1.4 6.3 0.2 0.2 1.7 3.2 1.7 1.3 48.7 0.4 12.7 7.3 8.3 13.4 13.1 7.5 7.7 14.6 10.0 12.6 7.8 20.1 10.8 100.2 38.5 42.2 0.0 14.5 14.5 1.2 15.3 3.4 1.1 38.3 26.7 55.1 70.1 9.9 95.6 70.9 170.8 83.8 29.6 197.6 75.7 1.4 31.7 161.0 116.9 9.7 10.1 11.0 2.0 20.1 139.5 3.6 36.4 25.3 50.6 187.4 3.7 1756.4 8.4 2.8 7.6 2.0 175.2 77.9 4.5 122.4 287.4 12.4 92.8 10.9 81.5 63.8 27.2 0.3 6.5 10.2 64.3 1.4 7.0 33.8 1653.7 7.5 3.5 6.6 62.4 50.4 0.5 4.8 3.5 13.4 1324.5 13.4 104.8 27.5 1.3 DAP ENSG00000112977 "Death associated protein" P51397 5 10679230-10761234 "Predicted intracellular proteins" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 193.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA029456 Uncertain Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Vesicles, Mitochondria" Nucleoplasm "HPA029456: AB_10601262" "unprognostic (2.70e-2)" "unprognostic (3.48e-1)" "unprognostic (2.25e-1)" "unprognostic (1.88e-2)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (4.05e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-3)" "unprognostic (3.50e-1)" "unprognostic (1.91e-2)" "unprognostic (3.03e-3)" "unprognostic (2.11e-1)" "unprognostic (2.39e-1)" "unprognostic (8.58e-3)" "unprognostic (2.04e-2)" 54.5 103.7 34.8 47.0 33.6 44.5 69.0 30.6 38.8 75.1 91.0 65.8 93.8 59.0 68.6 39.0 63.1 83.3 60.9 35.4 32.9 99.0 161.8 64.9 45.6 39.9 37.1 75.0 241.4 82.9 80.9 64.1 33.1 76.7 69.1 13.8 129.4 92.2 9.4 46.9 87.0 63.6 34.7 46.3 106.3 27.3 36.6 41.2 92.9 14.7 50.8 87.9 49.0 32.5 107.3 76.3 92.6 86.3 169.6 203.6 102.8 255.3 394.4 189.5 217.8 54.7 88.9 46.3 163.8 318.4 119.6 20.6 58.3 151.7 205.1 245.3 42.5 62.2 137.9 136.0 159.7 117.7 44.6 105.4 51.9 124.5 223.3 109.1 358.4 51.1 73.5 152.5 188.2 85.0 63.1 74.9 33.7 143.9 172.9 86.0 40.9 76.8 250.1 195.2 62.7 84.3 261.2 105.2 69.6 70.6 83.4 170.4 177.4 116.8 125.9 78.1 137.6 85.1 118.6 68.3 115.4 225.3 179.3 40.7 78.0 45.0 32.7 70.7 38.5 39.8 33.6 29.0 76.8 25.9 24.4 24.4 63.4 33.1 72.1 62.3 39.3 62.2 34.8 33.6 30.6 38.8 35.4 32.9 39.9 37.1 33.1 34.7 36.6 32.5 29.0 16.0 44.7 8.5 36.7 19.2 62.6 14.1 19.9 8.9 90.4 39.2 12.3 72.9 27.3 53.3 6.2 66.2 42.3 75.6 133.1 97.3 13.3 45.0 31.7 38.4 44.3 23.4 5.5 193.0 98.5 45.1 61.7 58.1 35.0 68.9 41.0 109.1 52.3 5.0 7.8 115.3 10.2 49.9 34.2 33.4 29.8 56.5 28.4 35.6 44.2 29.8 32.0 22.6 6.2 124.8 69.0 34.3 74.8 78.6 133.5 100.5 15.1 8.1 0.0 18.6 41.8 30.7 7.1 15.7 18.2 101.0 24.1 43.0 70.4 108.8 DAPK3 "ZIP, ZIPK" ENSG00000167657 "Death associated protein kinase 3" O43293 19 3958453-3971123 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Translation regulation" "Activator, Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028569 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" Cytosol Nucleoplasm "HPA028569: AB_10794319" "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.34e-3)" "prognostic favorable (2.01e-5)" "unprognostic (1.83e-1)" "unprognostic (2.37e-1)" "unprognostic (7.72e-3)" "unprognostic (2.16e-1)" "unprognostic (2.46e-2)" "unprognostic (4.95e-2)" "unprognostic (1.84e-3)" "unprognostic (7.64e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" 49.9 25.4 15.0 29.0 15.2 18.9 47.2 14.3 27.9 58.3 18.9 92.2 30.9 85.0 8.2 37.0 55.4 36.0 106.2 16.8 13.9 27.6 30.4 72.5 21.2 16.2 15.4 48.4 36.4 19.0 38.5 31.9 18.8 53.3 11.0 9.0 41.3 39.3 113.6 51.2 44.4 36.6 11.9 29.6 61.4 42.6 17.4 15.4 31.0 21.1 11.3 59.5 45.3 17.3 79.2 61.1 37.5 47.6 27.5 30.9 57.8 106.0 84.5 84.7 55.5 113.4 23.3 43.4 50.8 93.8 59.6 61.7 36.9 60.3 30.7 64.0 61.2 17.5 76.7 65.9 87.2 42.7 63.1 70.6 73.6 77.0 44.0 50.8 71.2 29.2 56.3 73.2 52.5 51.0 42.4 31.9 58.5 31.8 48.6 52.5 55.3 40.5 51.0 60.9 59.1 41.1 71.4 84.9 61.1 43.8 61.4 33.1 134.8 108.3 49.3 98.1 134.5 81.1 72.4 50.7 86.3 44.0 59.0 32.5 18.0 32.5 23.0 20.3 16.7 15.9 17.8 21.6 16.2 16.6 13.1 12.9 29.8 24.3 14.3 18.6 23.6 14.6 15.0 15.2 14.3 27.9 16.8 13.9 16.2 15.4 18.8 11.9 17.4 17.3 24.1 25.6 10.5 6.5 17.0 100.7 99.7 84.1 27.9 15.2 23.9 15.6 29.2 24.3 35.0 11.0 2.1 50.5 14.5 69.2 17.6 90.3 40.3 27.9 28.2 38.3 27.4 7.0 9.6 88.2 79.1 27.8 40.8 37.5 20.3 24.8 21.4 7.9 22.9 11.8 7.1 48.2 48.8 13.6 22.8 23.6 22.7 16.6 37.4 8.4 25.7 12.8 30.9 6.0 6.7 117.7 49.9 22.6 13.3 46.1 59.6 14.3 18.8 10.7 32.9 19.9 53.0 34.6 15.7 24.4 71.7 93.2 15.1 26.2 29.7 46.3 DBNL "ABP1, HIP-55, SH3P7" ENSG00000136279 "Drebrin like" Q9UJU6 7 44044640-44069456 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Endocytosis, Immunity, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 338.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020265, HPA027735" Enhanced Supported "Vesicles,Plasma membrane" NA NA 3500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Plasma membrane" "HPA020265: AB_1850723, HPA027735: AB_10603790" "unprognostic (9.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (2.25e-1)" "unprognostic (6.18e-3)" "unprognostic (1.83e-1)" "unprognostic (5.88e-2)" "unprognostic (8.92e-2)" "unprognostic (5.76e-3)" "unprognostic (5.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-1)" "unprognostic (1.46e-1)" "unprognostic (9.51e-2)" 58.1 51.6 44.2 62.8 45.1 76.6 51.3 41.7 50.4 72.4 39.9 54.6 34.7 56.0 20.2 189.0 47.8 47.2 49.2 45.8 45.2 50.7 51.1 57.8 99.6 46.2 44.8 38.0 44.3 38.4 47.8 34.9 48.4 57.0 30.6 9.4 57.5 38.0 34.3 59.9 64.7 44.8 44.3 119.5 54.7 20.8 44.6 64.8 47.6 16.4 89.1 60.3 92.0 43.4 57.6 89.1 60.5 56.6 77.0 49.7 46.0 95.9 93.6 111.5 91.5 90.0 82.5 132.3 70.0 126.1 133.6 101.9 35.6 130.6 40.7 70.6 38.9 51.9 73.8 52.4 78.5 75.8 70.3 46.6 53.3 107.1 35.2 71.5 74.1 83.9 63.8 49.3 105.5 91.5 136.5 85.3 43.1 72.9 73.0 69.4 48.1 64.5 69.8 90.5 65.6 89.8 69.6 121.5 24.4 43.8 94.0 99.4 121.1 82.7 75.5 49.5 113.6 102.7 49.4 81.2 78.3 83.2 183.8 263.3 377.1 295.0 190.3 422.7 148.3 253.9 138.0 155.0 362.5 261.7 136.5 145.1 357.4 192.4 437.9 376.6 183.1 558.8 44.2 45.1 41.7 50.4 45.8 45.2 46.2 44.8 48.4 44.3 44.6 43.4 49.9 44.8 36.2 10.7 105.4 17.6 34.1 62.9 19.4 33.0 26.7 24.0 30.6 25.8 42.2 31.3 35.5 78.9 101.6 58.5 45.0 87.0 10.3 30.7 39.3 44.8 37.8 45.8 7.4 73.2 146.4 39.3 54.6 50.7 65.9 42.3 32.5 22.5 176.0 40.4 6.7 50.0 38.7 129.6 48.6 10.6 37.0 113.4 55.2 7.5 338.3 42.5 112.3 5.5 11.4 105.9 74.0 33.8 50.2 31.5 49.0 33.6 21.6 38.6 6.6 29.0 54.6 24.4 12.8 64.4 26.7 87.3 69.5 51.9 44.0 51.1 DCAF6 "IQWD1, PC326" ENSG00000143164 "DDB1 and CUL4 associated factor 6" Q58WW2 1 167935783-168075843 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 641.3;tongue: 470.8" "Cell type enhanced" "Detected in all" "Early spermatids: 438.6;Excitatory neurons: 243.8;Late spermatids: 700.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054305 Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Focal adhesion sites" "HPA054305: AB_2682444" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-1)" "unprognostic (2.31e-1)" "unprognostic (2.20e-1)" "unprognostic (1.19e-1)" "unprognostic (5.42e-2)" "unprognostic (1.81e-1)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (1.74e-1)" "unprognostic (3.20e-2)" "unprognostic (9.21e-2)" "unprognostic (7.06e-2)" "unprognostic (6.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" 29.1 45.9 12.8 16.2 17.5 24.6 29.3 9.3 22.4 32.9 22.1 36.8 21.7 24.7 19.5 29.7 25.6 27.5 129.9 20.5 7.0 28.6 95.1 25.4 17.7 5.6 8.8 25.3 20.9 34.5 19.9 27.3 5.8 35.4 29.3 21.3 28.8 25.3 641.3 21.9 21.5 33.8 5.7 18.5 28.2 82.6 12.3 24.4 23.5 470.8 21.4 28.1 20.1 14.0 64.8 30.0 16.4 27.0 52.7 74.3 57.4 64.9 95.3 44.5 65.7 50.4 53.1 52.8 36.9 83.3 21.4 47.4 25.8 47.9 62.4 30.2 27.6 56.5 42.8 36.4 42.4 25.7 26.1 53.2 47.4 42.3 35.0 67.4 49.1 16.9 64.8 42.9 66.3 14.8 28.9 23.3 10.6 36.0 33.1 21.9 34.0 41.7 110.6 30.9 24.2 19.2 51.8 47.0 36.6 33.9 80.8 31.3 70.3 44.6 27.5 44.0 27.3 45.4 39.3 41.3 59.9 21.6 18.6 5.4 5.5 10.4 4.9 7.5 5.2 4.8 3.9 4.3 6.0 3.3 3.5 4.6 5.7 3.7 12.0 3.6 4.8 4.0 12.8 17.5 9.3 22.4 20.5 7.0 5.6 8.8 5.8 5.7 12.3 14.0 22.9 57.7 43.3 81.3 22.5 57.9 30.5 32.1 33.0 14.7 26.7 19.3 216.3 48.6 43.4 25.8 22.9 75.7 19.7 28.1 17.6 33.0 438.6 39.3 24.1 25.3 21.1 111.9 243.8 19.3 32.4 42.7 39.3 35.5 19.6 73.0 23.6 95.4 19.6 5.0 90.0 27.9 26.4 44.0 38.3 700.1 57.5 23.6 37.4 70.3 113.0 15.9 18.6 108.6 71.0 21.2 26.7 48.5 31.1 35.6 35.7 34.9 52.3 18.4 32.9 29.1 30.6 108.3 64.1 34.6 39.8 81.3 22.2 81.5 33.0 29.0 DCBLD1 "dJ94G16.1, MGC46341" ENSG00000164465 "Discoidin, CUB and LCCL domain containing 1" Q8N8Z6 6 117453817-117569858 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059667 Approved Approved Cytosol NA NA 22000000 "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA059667: AB_2684099" "unprognostic (1.00e-1)" "prognostic unfavorable (6.44e-5)" "unprognostic (1.08e-1)" "unprognostic (3.23e-3)" "unprognostic (2.47e-1)" "unprognostic (2.29e-3)" "unprognostic (1.53e-2)" "unprognostic (5.94e-3)" "unprognostic (3.74e-2)" "unprognostic (8.99e-2)" "unprognostic (5.69e-3)" "unprognostic (6.33e-2)" "prognostic unfavorable (8.57e-8)" "unprognostic (6.99e-2)" "unprognostic (4.72e-2)" "unprognostic (7.44e-2)" "unprognostic (1.36e-1)" 8.3 3.5 3.7 6.0 4.6 0.6 5.7 3.5 4.9 9.1 2.6 6.6 6.5 5.1 3.3 5.4 2.5 9.1 6.0 5.5 2.7 4.8 9.6 9.9 3.4 3.5 3.6 1.9 6.3 6.8 8.3 8.7 3.7 2.6 6.1 1.0 4.8 2.8 5.5 2.9 8.1 3.8 3.4 3.8 7.6 5.6 3.0 1.2 5.9 5.1 2.5 6.3 5.8 4.3 8.0 17.9 6.3 7.0 10.8 13.5 17.9 45.1 58.1 36.9 27.8 37.9 16.7 0.0 21.8 19.1 45.9 17.9 12.1 19.9 38.7 3.5 9.4 6.8 18.5 62.3 46.7 10.0 5.7 15.4 45.5 33.6 31.4 42.5 52.3 6.7 14.8 6.7 48.9 6.4 0.1 6.7 4.7 21.4 7.4 0.0 1.3 4.7 8.2 9.4 19.0 0.3 33.0 3.6 5.3 9.0 4.7 13.1 38.9 0.0 44.1 12.6 19.8 18.9 5.4 5.3 18.7 9.6 16.5 0.0 0.2 0.0 0.6 0.2 0.1 0.0 0.8 1.2 0.2 0.0 1.0 1.3 0.0 0.4 0.1 0.4 0.9 0.5 3.7 4.6 3.5 4.9 5.5 2.7 3.5 3.6 3.7 3.4 3.0 4.3 16.0 16.0 18.8 5.2 3.0 5.2 3.7 12.3 0.6 8.4 4.8 3.6 5.3 12.8 14.4 5.5 6.2 31.5 4.9 9.5 1.9 7.0 33.0 5.3 15.1 11.0 4.2 3.2 20.8 4.8 6.1 6.6 13.7 7.9 1.3 13.9 17.2 9.6 5.8 5.0 3.3 8.5 6.1 7.0 15.0 10.9 0.9 5.8 8.8 13.1 2.5 1.1 6.2 12.1 11.6 10.4 7.7 0.4 1.6 3.0 11.1 2.7 5.7 3.5 13.1 5.1 27.6 2.2 10.6 6.8 6.0 18.2 5.1 2.1 11.1 5.4 DCLK2 "DCAMKL2, DCDC3, DCDC3B, DCK2, MGC45428" ENSG00000170390 "Doublecortin like kinase 2" Q8N568 4 150078445-150257438 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.0" "Group enriched" "Detected in many" 6 "Astrocytes: 501.1;Excitatory neurons: 189.8;Inhibitory neurons: 173.2;Oligodendrocyte precursor cells: 172.4" "Cancer enriched" "Detected in many" 17 "glioma: 53.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 23.6;BJ: 11.8;BJ hTERT+: 24.9;fHDF/TERT166: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015770 Enhanced Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA015770: AB_1847509" "unprognostic (7.37e-2)" "unprognostic (1.56e-3)" "unprognostic (9.30e-2)" "unprognostic (1.49e-2)" "unprognostic (4.06e-1)" "unprognostic (6.24e-3)" "unprognostic (1.90e-1)" "unprognostic (7.38e-3)" "unprognostic (2.18e-1)" "prognostic favorable (3.25e-4)" "prognostic favorable (2.48e-4)" "unprognostic (6.87e-2)" "unprognostic (3.93e-3)" "unprognostic (3.74e-3)" "unprognostic (4.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.45e-2)" 1.7 2.8 45.8 0.9 42.0 0.5 1.4 34.6 43.6 2.0 7.7 5.6 1.4 2.7 2.0 1.5 1.9 2.5 12.2 59.0 41.2 2.3 0.6 2.1 0.4 41.2 46.6 2.9 2.2 0.6 8.3 1.5 38.4 2.7 2.0 18.4 0.8 2.0 1.2 1.0 2.2 4.7 46.6 1.2 2.3 2.8 42.7 0.2 2.6 1.4 0.3 2.6 1.3 46.8 1.2 4.2 23.6 3.7 0.0 1.1 0.4 11.8 24.9 3.5 0.9 0.1 0.0 0.0 0.4 11.0 3.6 0.1 3.5 0.0 4.4 5.1 2.1 0.0 7.0 0.0 5.0 0.7 0.7 0.6 0.0 2.2 0.2 2.2 1.2 0.6 0.0 0.1 2.5 0.2 0.4 0.0 0.5 0.3 1.6 0.0 2.8 1.0 0.1 1.0 9.2 9.1 4.7 3.4 1.0 2.0 0.0 0.1 2.1 3.3 1.3 2.2 1.3 1.1 0.0 0.1 3.1 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 45.8 42.0 34.6 43.6 59.0 41.2 41.2 46.6 38.4 46.6 42.7 46.8 10.7 0.0 0.0 501.1 0.6 0.5 0.1 0.0 0.6 26.2 2.8 2.2 10.5 1.5 0.7 3.7 16.7 0.0 0.0 0.8 0.0 0.4 0.1 0.4 4.6 7.6 3.0 0.0 189.8 0.7 0.0 3.4 1.1 0.5 4.5 5.7 7.5 0.0 1.6 35.3 173.2 0.3 0.0 0.6 3.4 0.3 1.8 0.7 5.4 43.1 0.2 31.2 0.0 172.4 37.6 0.1 0.4 3.8 0.3 0.6 0.0 0.4 0.1 9.6 13.1 5.6 9.2 0.1 2.0 0.1 0.6 0.3 0.9 6.6 1.4 0.2 DCTN1 ENSG00000204843 "Dynactin subunit 1" Q14203 2 74361154-74392087 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Amyotrophic lateral sclerosis, Cancer-related genes, Neurodegeneration, Neuropathy, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009108, HPA034635, HPA071875" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB009108: AB_2090601, HPA034635: AB_2674256, HPA071875: " "unprognostic (1.14e-1)" "unprognostic (7.19e-2)" "unprognostic (1.33e-3)" "unprognostic (4.08e-2)" "unprognostic (1.20e-1)" "unprognostic (2.67e-1)" "unprognostic (4.61e-3)" "unprognostic (2.11e-2)" "unprognostic (2.79e-1)" "unprognostic (3.73e-3)" "unprognostic (1.87e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.34e-7)" "unprognostic (5.41e-2)" "unprognostic (3.11e-1)" "unprognostic (7.86e-3)" "unprognostic (1.12e-3)" 43.3 40.0 90.5 27.0 94.7 23.7 37.4 76.4 113.2 44.3 20.8 51.3 22.2 51.4 17.0 42.6 38.7 28.2 82.6 99.9 80.1 27.6 18.2 36.0 22.8 110.9 85.1 39.2 28.6 118.0 61.2 32.6 112.6 30.0 25.5 43.5 56.3 38.0 87.6 44.2 32.2 49.9 76.0 26.5 39.5 51.3 101.9 34.7 31.3 63.4 24.6 47.6 39.0 116.2 65.0 74.7 68.4 71.9 122.5 90.7 55.2 102.0 105.2 127.0 89.9 99.9 48.6 88.8 40.8 213.0 70.1 63.5 84.3 129.5 96.1 111.2 85.0 92.5 55.6 84.7 94.4 50.7 109.3 109.6 62.0 138.3 82.3 86.9 110.3 79.4 40.3 61.4 97.3 55.6 92.8 52.5 74.0 78.6 78.3 82.3 120.1 63.8 70.2 39.6 83.3 74.1 57.1 67.7 60.6 59.0 43.5 36.5 84.3 115.0 82.7 50.0 77.2 37.8 32.7 78.9 107.6 81.4 82.5 8.3 11.3 12.7 14.4 13.0 11.7 10.1 8.2 10.8 11.2 6.8 5.6 6.3 9.2 9.2 15.6 8.8 7.7 16.5 90.5 94.7 76.4 113.2 99.9 80.1 110.9 85.1 112.6 76.0 101.9 116.2 28.6 32.1 25.4 9.8 23.2 10.1 10.3 19.1 25.6 27.2 19.6 17.8 56.4 18.6 20.0 29.5 25.0 29.8 19.4 41.0 19.6 22.5 7.3 21.5 32.8 26.6 16.7 27.3 28.4 19.9 27.1 25.1 49.5 27.8 29.2 30.8 29.6 19.9 28.8 90.9 26.7 31.8 24.4 21.0 11.3 9.3 44.7 21.2 16.0 8.4 27.3 14.9 23.7 12.1 29.7 26.6 33.6 51.9 24.7 9.6 34.2 19.6 19.4 45.5 19.7 28.3 30.0 40.6 38.5 29.0 11.8 25.2 20.0 33.9 24.9 10.7 DDAH1 DDAH ENSG00000153904 "Dimethylarginine dimethylaminohydrolase 1" O94760 1 85318481-85578363 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 131.8;kidney: 124.8" "Cell type enhanced" "Detected in many" "Astrocytes: 364.4;Excitatory neurons: 197.4;Oligodendrocyte precursor cells: 182.4;Proximal tubular cells: 283.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 239.4;LHCN-M2: 179.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006308, HPA071064" Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA 350000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" Nucleoli "HPA006308: AB_1847532, HPA071064: " "unprognostic (1.44e-2)" "unprognostic (2.43e-1)" "prognostic favorable (5.99e-4)" "unprognostic (6.82e-2)" "unprognostic (1.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.55e-1)" "unprognostic (3.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.02e-2)" "unprognostic (3.62e-2)" "unprognostic (1.56e-1)" "prognostic favorable (5.21e-6)" "unprognostic (5.37e-2)" "unprognostic (9.06e-2)" "unprognostic (5.81e-2)" "unprognostic (1.56e-2)" 10.3 28.6 95.9 12.8 100.9 0.6 18.8 61.5 131.8 22.4 73.4 45.1 40.1 10.8 76.5 12.6 36.5 25.5 17.4 102.0 77.3 124.8 79.5 26.4 2.6 58.6 84.8 2.9 27.5 21.1 6.3 11.6 62.6 28.5 45.3 34.6 17.7 18.6 30.4 5.6 39.7 16.5 59.5 10.6 29.7 19.1 106.6 1.0 28.9 14.0 2.0 19.2 2.6 80.3 63.1 7.6 36.0 6.9 84.1 78.0 9.2 155.9 120.0 63.6 75.6 89.9 16.5 0.1 39.2 239.4 38.3 17.8 79.7 15.0 93.0 0.3 29.5 0.2 22.3 31.8 40.9 57.6 3.2 60.5 2.0 50.4 24.9 85.5 75.9 0.0 0.1 6.0 179.7 7.5 3.0 0.3 25.5 124.6 22.6 0.0 63.1 0.9 113.4 46.3 59.2 115.0 18.0 56.3 9.1 38.7 29.6 4.9 107.7 31.6 27.0 11.7 57.8 0.0 0.1 0.2 1.6 0.1 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.9 100.9 61.5 131.8 102.0 77.3 58.6 84.8 62.6 59.5 106.6 80.3 14.1 35.3 43.4 364.4 2.6 13.8 4.6 6.8 5.7 4.5 31.2 13.8 11.8 61.5 13.6 69.9 4.2 2.7 0.4 75.3 125.2 15.9 22.5 36.9 9.8 7.5 34.2 2.7 197.4 31.2 0.9 13.9 47.9 24.2 0.0 59.3 8.2 102.8 1.1 0.0 51.0 86.9 8.2 2.2 5.5 25.6 15.8 2.4 12.4 23.4 0.6 68.4 0.0 182.4 9.6 44.5 69.4 74.9 0.0 33.6 68.7 283.3 36.5 9.4 13.1 15.3 18.6 4.6 5.4 32.6 14.3 0.8 2.5 13.5 106.7 8.3 DDB2 "DDBB, FLJ34321, UV-DDB2, XPE" ENSG00000134574 "Damage specific DNA binding protein 2" Q92466 11 47214465-47239217 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;monocytes: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025912, HPA058406" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cell Junctions" "CAB025912: , HPA058406: AB_2683708" "prognostic favorable (7.29e-4)" "prognostic favorable (1.58e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.20e-4)" "unprognostic (4.29e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-2)" "unprognostic (6.18e-2)" "unprognostic (2.25e-1)" "unprognostic (3.58e-3)" "unprognostic (3.53e-1)" "unprognostic (1.94e-1)" "unprognostic (4.57e-3)" "unprognostic (1.21e-2)" "unprognostic (4.25e-2)" "unprognostic (9.82e-3)" "unprognostic (1.07e-1)" 13.2 22.5 2.6 8.2 3.2 11.6 13.5 3.4 3.6 12.5 3.4 12.8 7.6 12.7 11.7 24.8 17.6 12.5 6.8 2.5 2.4 4.4 27.0 12.2 14.7 3.4 2.7 11.6 14.4 4.8 4.7 6.8 3.5 9.7 14.9 2.3 14.4 11.7 6.2 46.7 10.2 13.9 2.7 11.3 9.5 4.5 3.2 23.5 5.5 6.9 17.0 11.2 14.1 3.6 23.7 62.3 25.9 19.3 16.6 32.7 29.9 26.0 58.8 32.0 37.1 10.1 14.1 56.6 5.3 23.2 23.6 40.8 14.6 51.8 15.7 14.5 27.5 13.3 55.7 46.7 15.8 15.9 34.4 43.4 58.0 15.9 35.2 10.2 94.2 14.7 3.5 27.0 52.7 44.4 60.4 7.7 8.4 31.1 22.3 30.3 5.6 30.6 13.5 22.7 13.2 16.7 31.2 8.7 8.1 30.8 56.1 5.5 41.2 96.8 44.1 21.3 12.6 27.6 22.4 12.5 37.0 20.2 35.9 9.8 12.8 20.2 19.3 18.4 18.8 18.3 20.1 18.8 10.4 14.5 14.8 15.7 3.7 14.1 15.8 0.3 47.7 15.9 2.6 3.2 3.4 3.6 2.5 2.4 3.4 2.7 3.5 2.7 3.2 3.6 13.8 16.0 22.2 7.8 25.1 38.9 39.7 28.1 75.1 5.0 18.0 25.8 7.8 11.5 16.3 5.5 10.4 3.6 21.3 11.1 9.8 12.5 1.5 5.2 8.1 19.5 7.7 19.1 6.6 13.8 9.0 16.0 18.3 9.5 22.8 31.2 15.0 16.6 17.5 1.7 1.4 12.6 16.2 17.5 12.8 2.1 19.0 16.8 19.6 24.4 135.5 9.6 35.0 1.0 10.6 19.9 9.8 10.5 34.1 8.9 15.7 7.7 13.9 12.8 0.0 12.1 14.0 3.1 8.6 34.5 30.3 1.5 34.3 25.4 16.5 26.5 DENND2B "HTS1, p126, ST5" ENSG00000166444 "DENN domain containing 2B" P78524 11 8693351-8910951 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 3.2;Cardiomyocytes: 6.2;Cytotrophoblasts: 3.7;Extravillous trophoblasts: 1.8;Fibroblasts: 7.1;Hofbauer cells: 5.8;Smooth muscle cells: 5.7;Syncytiotrophoblasts: 2.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "non-classical monocyte: 2.9" "Lineage enriched" "Detected in single" 4 "monocytes: 2.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 95.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046796 Approved Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA046796: AB_2679812" "unprognostic (1.88e-3)" "unprognostic (2.18e-2)" "unprognostic (2.19e-1)" "unprognostic (1.88e-2)" "unprognostic (4.17e-2)" "unprognostic (2.46e-1)" "unprognostic (6.42e-2)" "unprognostic (1.17e-1)" "unprognostic (1.72e-1)" "unprognostic (5.56e-2)" "unprognostic (3.67e-2)" "unprognostic (1.28e-1)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (1.60e-1)" "unprognostic (1.54e-1)" 26.3 60.0 22.0 19.2 20.4 3.4 26.6 26.6 23.2 72.7 38.2 85.4 28.8 130.3 33.2 62.7 104.6 34.6 35.0 19.1 22.3 29.4 27.4 28.8 12.1 29.7 32.6 69.2 27.5 15.4 21.5 26.4 18.3 45.4 26.7 36.5 37.5 62.9 21.9 22.2 30.3 117.2 21.3 59.7 56.9 41.0 28.0 17.5 36.6 11.1 15.1 65.0 50.4 17.1 32.6 4.9 51.8 9.0 16.8 17.6 2.5 28.9 95.8 27.5 25.4 6.8 34.0 1.0 17.2 52.7 12.1 32.2 10.0 41.7 10.8 4.4 12.7 0.0 16.7 22.8 26.9 0.2 0.2 60.8 11.6 15.6 20.1 56.0 5.5 5.0 6.7 2.8 45.4 3.5 1.8 1.5 7.9 32.2 7.7 1.1 31.5 2.0 37.5 23.4 9.8 31.7 25.7 32.1 19.8 17.7 5.4 1.1 14.9 15.8 24.7 50.6 22.8 8.0 15.5 0.2 24.1 0.2 30.4 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.6 0.4 0.0 0.0 0.4 0.0 2.9 0.0 0.1 0.4 22.0 20.4 26.6 23.2 19.1 22.3 29.7 32.6 18.3 21.3 28.0 17.1 3.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 3.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.8 7.1 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 DIAPH3 "AN, AUNA1, DRF3, FLJ34705, NSDAN" ENSG00000139734 "Diaphanous related formin 3" Q9NSV4 13 59665583-60163928 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.1;testis: 18.9" "Cell type enriched" "Detected in many" 5 "Early spermatids: 414.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032151 Supported "Plasma membrane,Microtubules" NA Yes "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Microtubules" "HPA032151: AB_2674181" "unprognostic (3.78e-2)" "unprognostic (1.28e-2)" "prognostic favorable (9.04e-4)" "prognostic unfavorable (4.18e-4)" "unprognostic (2.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.27e-4)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.74e-2)" "unprognostic (2.19e-1)" "unprognostic (5.22e-5)" "unprognostic (3.59e-3)" "unprognostic (5.31e-5)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "unprognostic (2.74e-3)" 0.4 0.1 0.1 1.7 0.2 7.1 0.8 0.3 0.3 0.3 0.2 1.9 1.9 0.6 0.0 2.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 1.2 2.4 0.2 0.3 0.1 0.2 0.1 0.0 3.5 0.2 0.1 2.1 0.0 0.5 0.0 0.0 1.3 1.6 2.6 0.1 0.5 1.6 18.9 0.3 5.4 0.1 0.0 2.4 0.6 0.7 0.2 47.7 15.6 15.8 9.1 2.7 7.1 26.9 65.0 28.7 64.2 55.6 41.7 31.4 15.9 5.2 33.4 16.7 31.7 26.0 25.5 96.9 18.0 17.9 22.7 37.6 9.5 4.1 31.2 17.4 2.8 0.6 39.2 26.3 16.3 29.2 14.0 17.8 21.9 61.8 6.9 28.0 10.2 14.7 22.5 8.9 18.8 38.9 12.9 19.9 9.6 8.3 14.3 33.2 22.8 9.5 33.8 16.7 16.8 29.3 40.5 25.9 13.7 54.5 14.7 17.1 24.4 10.9 15.2 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.3 0.3 0.1 0.2 0.2 0.3 0.2 0.1 0.3 0.2 0.6 54.5 3.4 39.8 1.9 3.7 0.8 2.1 2.8 0.0 3.9 1.5 1.0 2.8 1.8 0.0 0.0 21.1 1.1 3.8 5.9 1.3 414.4 2.5 3.5 2.1 0.0 26.7 5.6 4.0 30.7 5.8 9.7 9.3 0.0 78.8 1.8 0.4 6.1 0.0 3.3 2.6 2.0 1.0 1.2 56.0 0.6 1.5 0.0 5.6 0.1 3.5 2.1 19.1 1.8 1.5 0.2 0.0 18.9 0.4 1.1 5.4 0.2 0.0 0.0 0.0 7.9 39.2 17.8 11.6 1.1 7.3 2.2 2.8 5.6 1.5 DIPK1A "FAM69A, FLJ23493" ENSG00000154511 "Divergent protein kinase domain 1A" Q5T7M9 1 92832737-92961522 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 30.6;Syncytiotrophoblasts: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015718, HPA017281" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 15: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Nucleoplasm "HPA015718: AB_1848405, HPA017281: AB_1848406" "prognostic favorable (8.96e-4)" "unprognostic (1.00e-1)" "unprognostic (6.17e-2)" "unprognostic (1.50e-3)" "unprognostic (1.43e-1)" "unprognostic (3.77e-3)" "unprognostic (3.63e-3)" "unprognostic (1.08e-1)" "unprognostic (1.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.19e-1)" "unprognostic (5.04e-2)" "prognostic unfavorable (1.45e-7)" "unprognostic (1.26e-2)" "unprognostic (5.99e-2)" "unprognostic (2.57e-1)" "unprognostic (1.66e-2)" 18.8 4.2 20.2 14.5 23.3 10.0 9.9 22.3 29.5 7.8 14.6 15.2 11.7 15.7 4.7 12.0 9.5 14.6 6.7 20.4 21.2 7.9 32.8 6.0 14.9 21.7 20.6 7.5 4.5 15.1 3.9 16.9 22.3 11.8 15.9 8.3 7.5 13.8 11.3 7.4 11.0 25.5 23.1 10.6 11.9 8.6 20.9 16.1 8.0 7.5 12.2 14.8 6.2 31.0 11.2 12.6 4.6 11.5 17.6 33.5 5.9 33.9 69.0 18.6 37.8 6.7 2.3 38.3 6.0 62.1 38.0 13.6 0.9 25.3 30.5 15.7 12.2 1.2 9.2 17.1 6.3 3.4 2.1 19.6 19.8 40.8 9.7 31.8 0.3 22.7 13.4 37.7 24.1 4.0 12.4 3.1 8.6 18.4 4.6 11.4 36.2 11.5 2.6 11.2 11.8 9.5 9.7 9.2 12.7 10.6 4.3 1.1 1.3 22.1 17.0 43.0 12.0 57.7 60.2 44.0 10.4 2.2 2.0 0.1 1.8 0.1 19.3 0.9 15.5 43.4 22.3 15.5 8.6 26.9 25.6 22.2 0.5 24.2 0.6 14.1 21.9 12.3 20.2 23.3 22.3 29.5 20.4 21.2 21.7 20.6 22.3 23.1 20.9 31.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 30.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 5.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 25.3 0.7 0.0 0.0 0.0 DKK1 "DKK-1, SK" ENSG00000107984 "Dickkopf WNT signaling pathway inhibitor 1" O94907 10 52314281-52318042 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 34.0;placenta: 48.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 486.2;Endometrial stromal cells: 337.6;Pancreatic endocrine cells: 194.6;Prostatic glandular cells: 992.9;Urothelial cells: 320.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 1141.1;BJ hTERT+: 620.0;CACO-2: 1011.3;fHDF/TERT166: 1590.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in other tissues" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.65e-2)" "unprognostic (4.21e-2)" "unprognostic (7.09e-2)" "unprognostic (7.99e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.35e-8)" "unprognostic (7.93e-2)" "prognostic unfavorable (7.80e-6)" "unprognostic (1.54e-1)" "unprognostic (6.87e-2)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.81e-1)" "unprognostic (1.68e-1)" "unprognostic (7.47e-3)" "unprognostic (4.05e-1)" "unprognostic (1.19e-1)" "unprognostic (2.06e-2)" 22.0 0.3 0.6 0.3 0.8 0.0 5.6 1.1 0.9 34.0 0.4 0.3 0.1 1.8 0.0 7.9 0.4 3.9 0.7 0.5 1.5 0.6 0.2 1.2 0.4 0.6 1.6 1.0 0.2 0.1 0.1 48.9 0.8 4.8 0.1 7.0 2.3 1.9 0.3 16.5 0.2 0.2 0.7 0.8 1.2 0.2 1.7 0.0 0.3 0.0 0.5 21.9 10.6 0.6 315.3 215.8 0.1 32.4 149.6 30.4 0.1 1141.1 620.0 383.8 202.5 1011.3 64.2 0.0 1.6 1590.5 93.5 245.1 0.3 130.7 361.3 0.1 0.7 0.0 4.4 26.2 31.8 0.0 0.1 30.3 16.0 83.0 488.3 19.8 35.8 0.0 0.0 0.1 255.8 135.7 0.0 0.1 0.2 13.7 543.9 0.2 34.8 0.0 148.6 25.6 0.2 342.4 102.8 1.1 17.7 0.4 1.1 0.9 78.9 0.2 0.2 338.5 211.9 0.1 0.3 0.1 4.6 0.1 37.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.1 0.9 0.5 1.5 0.6 1.6 0.8 0.7 1.7 0.6 1.9 25.6 0.0 0.0 1.0 5.4 486.2 28.5 0.0 0.2 0.8 6.9 1.1 0.0 15.2 0.0 0.0 4.6 0.0 0.9 0.0 10.7 1.2 11.0 337.6 8.5 0.0 0.0 1.2 4.1 4.0 91.5 2.6 8.1 4.5 0.0 1.1 0.0 9.3 0.0 2.2 2.4 6.1 0.0 1.6 0.6 0.0 4.9 0.0 1.0 0.0 6.1 0.0 1.5 0.2 194.6 5.0 0.0 1.3 992.9 0.4 0.0 9.8 0.4 0.0 0.0 10.6 0.4 2.2 1.4 3.1 8.3 2.8 0.0 1.0 320.0 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DLGAP4 "DAP4, KIAA0964, SAPAP4" ENSG00000080845 "DLG associated protein 4" Q9Y2H0 20 36306336-36528637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 213.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054105, HPA056378" Approved Approved "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA054105: AB_2682381, HPA056378: " "unprognostic (1.11e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-2)" "prognostic unfavorable (2.24e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.73e-6)" "unprognostic (1.23e-1)" "prognostic favorable (9.88e-5)" "unprognostic (1.28e-1)" "unprognostic (2.18e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.07e-1)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" 55.4 47.5 39.0 23.5 31.4 7.5 40.3 2.8 45.9 51.7 2.6 71.4 21.2 64.5 12.5 31.7 45.2 26.4 58.4 39.3 12.3 34.3 37.3 60.5 16.6 5.4 18.1 48.4 47.8 13.8 36.4 26.5 10.5 44.7 15.0 25.4 37.8 30.6 130.8 86.8 37.1 42.5 2.8 32.9 36.5 29.3 29.1 14.7 43.3 45.9 14.8 56.2 46.6 20.6 49.9 44.2 53.0 44.1 49.0 79.9 53.2 73.2 66.5 70.0 48.2 67.4 30.9 14.0 38.5 103.3 61.9 46.7 14.3 75.1 51.8 22.5 5.2 31.8 22.7 46.2 70.9 12.9 26.5 52.9 57.0 83.1 57.6 54.2 69.7 19.5 22.5 37.2 53.6 37.0 26.3 49.0 23.2 36.2 93.4 26.1 14.0 19.4 33.0 24.3 34.8 47.9 48.0 96.0 60.0 53.7 55.3 22.3 71.2 212.1 64.6 92.6 40.9 12.7 9.8 15.1 84.9 16.2 85.4 2.7 16.5 26.9 15.0 17.3 11.9 19.5 13.5 10.7 14.5 20.8 10.1 8.1 23.6 9.6 17.9 17.4 11.9 12.6 39.0 31.4 2.8 45.9 39.3 12.3 5.4 18.1 10.5 2.8 29.1 20.6 30.4 16.0 20.5 34.0 25.2 66.4 53.8 30.6 9.1 34.9 30.2 21.0 27.9 22.8 22.9 12.9 8.4 23.1 23.7 27.2 7.9 53.0 69.9 25.9 47.7 36.6 63.3 4.4 77.9 55.7 52.3 40.1 23.4 29.4 12.6 35.7 27.8 17.5 27.2 74.0 93.4 35.0 20.3 22.4 54.4 213.4 29.8 23.9 10.6 37.5 47.5 38.7 21.6 81.4 13.2 84.4 25.0 26.4 8.9 72.9 25.8 20.4 28.3 29.5 72.3 28.8 51.0 13.7 30.3 13.2 71.7 55.1 20.7 29.8 20.6 52.3 DNMBP "ARHGEF36, KIAA1010, Tuba" ENSG00000107554 "Dynamin binding protein" Q6XZF7 10 99875577-100009947 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037878, HPA058216" Uncertain Approved "Nucleoli,Nuclear bodies,Golgi apparatus,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Nucleoli, Golgi apparatus, Cytosol" "Nuclear bodies" "HPA037878: AB_10675622, HPA058216: AB_2683640" "unprognostic (3.25e-1)" "unprognostic (8.19e-2)" "unprognostic (1.86e-1)" "prognostic favorable (4.95e-6)" "unprognostic (3.92e-2)" "unprognostic (4.13e-1)" "unprognostic (9.79e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.02e-1)" "unprognostic (8.67e-3)" "unprognostic (4.03e-2)" "unprognostic (5.07e-3)" "unprognostic (6.52e-2)" "unprognostic (4.95e-2)" "unprognostic (1.28e-1)" "prognostic favorable (6.15e-4)" 13.6 6.0 3.6 5.5 3.7 10.3 10.2 6.2 5.3 15.8 8.6 17.7 22.5 9.6 12.5 10.2 11.3 11.0 7.5 4.7 4.2 20.6 13.1 8.4 4.6 3.7 3.6 11.5 17.6 31.7 3.9 10.5 3.8 8.9 20.7 15.8 8.4 12.8 13.4 27.4 27.2 8.8 3.0 7.7 23.8 6.9 5.2 20.1 8.1 11.1 5.2 19.8 17.7 3.1 25.7 20.7 18.4 29.2 32.9 27.4 4.4 45.2 43.6 21.5 20.7 14.2 38.0 26.6 18.9 34.9 11.8 19.9 21.6 26.1 29.9 1.4 6.7 3.8 23.7 10.0 17.1 2.6 1.8 13.0 5.7 26.6 23.4 75.5 52.1 8.5 3.6 0.0 44.1 3.2 4.5 5.1 17.7 18.0 12.3 5.5 18.7 1.4 36.6 21.9 3.1 4.2 7.4 1.9 5.7 25.3 1.5 2.4 63.4 16.0 15.3 13.1 29.8 2.1 1.7 36.3 15.2 8.4 12.2 0.0 0.8 0.2 0.7 1.2 0.7 1.2 0.1 0.4 0.3 1.9 0.1 0.3 0.7 2.1 1.2 0.3 0.0 0.6 3.6 3.7 6.2 5.3 4.7 4.2 3.7 3.6 3.8 3.0 5.2 3.1 6.8 9.6 11.0 11.1 14.8 35.1 7.2 5.0 5.2 6.3 9.3 6.3 6.1 12.8 11.2 12.9 35.5 7.7 4.4 36.7 3.9 7.5 1.0 27.0 11.0 12.6 3.6 0.0 15.9 14.3 1.4 17.6 26.0 43.9 2.5 4.1 11.4 12.8 4.7 13.5 24.8 25.0 6.1 10.7 9.6 3.2 13.7 20.5 3.6 23.4 3.3 4.3 0.0 10.6 2.6 19.3 23.6 9.1 6.1 4.0 36.5 3.7 19.9 26.6 0.0 4.3 6.9 4.2 9.3 9.0 45.6 3.7 4.3 15.0 28.4 21.8 DOCK10 "KIAA0694, ZIZ3" ENSG00000135905 "Dedicator of cytokinesis 10" Q96BY6 2 224765090-225042468 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.1;lymphoid tissue: 32.1" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1806.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 45.5;GAMG: 73.4;HDLM-2: 52.7;TIME: 48.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058106 Enhanced Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA058106: AB_2683606" "unprognostic (6.95e-2)" "unprognostic (1.41e-2)" "unprognostic (1.05e-2)" "unprognostic (2.03e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-3)" "unprognostic (1.19e-1)" "unprognostic (6.92e-2)" "unprognostic (3.44e-2)" "unprognostic (3.80e-1)" "unprognostic (3.22e-3)" "unprognostic (3.39e-1)" "unprognostic (1.24e-2)" "unprognostic (1.01e-1)" "unprognostic (2.99e-2)" "unprognostic (2.54e-1)" "unprognostic (7.72e-2)" 4.5 8.2 22.6 18.8 49.2 10.2 3.8 33.7 33.4 8.7 9.7 6.3 4.1 3.2 1.1 3.2 2.4 6.3 1.6 28.7 35.1 3.2 5.5 7.6 27.8 45.5 38.4 17.7 1.7 2.0 1.0 2.3 48.9 1.6 6.5 5.7 2.5 1.7 1.2 5.0 12.5 4.3 32.0 29.8 6.7 2.2 37.9 32.1 2.7 0.8 19.9 6.4 4.4 83.1 0.0 21.4 6.7 0.0 8.5 17.9 0.0 45.5 36.8 21.3 15.8 0.0 0.0 0.6 0.1 28.9 73.4 0.5 0.0 0.1 16.9 52.7 0.0 0.6 4.5 0.0 0.3 4.4 2.1 4.3 0.4 31.0 12.0 8.3 21.4 7.0 0.1 42.1 36.4 2.1 8.0 6.1 2.6 0.0 5.0 10.5 9.8 6.2 1.1 0.1 0.4 5.5 0.0 0.0 4.8 1.2 1.4 20.0 48.2 22.8 5.7 10.9 15.6 0.0 0.0 0.0 32.2 29.6 10.1 3.0 3.3 0.2 6.5 9.2 6.6 7.2 10.9 9.1 6.9 4.5 10.5 9.3 0.1 14.3 11.8 2.8 8.4 4.5 22.6 49.2 33.7 33.4 28.7 35.1 45.5 38.4 48.9 32.0 37.9 83.1 3.7 3.2 9.1 4.2 47.1 4.7 0.6 0.3 8.0 7.9 0.8 4.3 1.2 0.0 2.5 5.5 0.0 0.3 39.5 0.8 1.9 0.1 3.2 0.2 2.3 3.2 2.4 5.5 8.0 0.0 0.2 4.9 5.1 0.5 36.7 64.0 2.5 1.4 30.6 97.6 244.2 3.8 0.0 54.2 39.7 2.8 0.6 51.0 8.8 201.4 38.3 1.2 38.1 400.6 1806.0 0.2 0.3 0.0 43.5 0.5 0.2 0.3 2.6 1.8 13.1 2.5 18.9 0.3 1.1 2.1 4.1 0.8 75.1 31.4 2.5 0.7 DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.5" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1712.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB033241: AB_2094323, HPA045210: AB_2679256" "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" 22.2 13.2 7.2 22.6 12.8 10.3 16.7 5.7 10.4 18.8 2.4 11.9 21.9 14.9 8.4 17.1 14.3 25.7 8.9 7.4 12.9 12.6 68.5 29.6 16.6 12.4 9.4 24.0 11.8 9.2 6.2 4.5 12.1 9.9 10.1 3.3 15.0 13.4 5.8 7.1 19.4 18.2 6.9 24.7 8.4 3.7 12.9 17.0 10.3 10.1 12.0 18.2 14.2 24.4 22.2 6.2 7.8 0.2 42.4 72.5 0.1 35.2 31.9 32.1 23.6 0.0 9.2 11.7 50.6 32.9 5.1 5.2 0.0 8.3 58.7 11.6 7.3 10.0 11.1 0.2 18.8 4.5 0.6 57.5 3.0 25.7 29.3 67.7 26.8 6.8 0.4 36.4 17.0 0.0 23.6 6.4 0.9 0.2 7.5 0.1 37.1 18.6 39.4 0.1 11.1 8.8 30.1 2.5 0.3 0.8 0.0 10.2 30.9 69.2 5.0 56.4 70.6 3.0 0.1 0.2 10.2 12.6 56.2 18.2 61.1 4.1 11.6 29.5 14.8 2.2 13.3 11.0 32.7 4.9 12.5 11.1 59.8 13.3 27.1 0.9 15.8 21.9 7.2 12.8 5.7 10.4 7.4 12.9 12.4 9.4 12.1 6.9 12.9 24.4 25.5 16.0 39.1 23.8 15.4 7.6 8.8 9.4 18.8 2.5 8.4 8.3 5.3 40.0 11.5 7.3 0.0 0.2 19.2 3.3 5.9 2.5 7.0 1.5 15.2 14.7 3.0 13.3 258.6 6.4 0.2 30.0 10.7 1.7 9.5 4.5 17.2 54.2 17.1 0.0 30.5 5.5 6.1 130.4 27.0 4.0 33.5 73.7 3.6 105.9 98.1 4.8 27.8 34.2 1712.3 5.3 2.1 18.8 17.0 4.9 21.0 6.6 8.6 0.1 13.1 16.0 17.7 1.2 3.1 19.7 5.5 0.1 31.4 5.1 6.8 9.3 DRAM1 "DRAM, FLJ11259" ENSG00000136048 "DNA damage regulated autophagy modulator 1" Q8N682 12 101877580-102012130 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 94.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 321.8;Early spermatids: 145.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "BJ hTERT+: 532.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (8.82e-2)" "unprognostic (1.80e-1)" "unprognostic (7.19e-2)" "prognostic favorable (6.52e-8)" "unprognostic (1.15e-2)" "unprognostic (2.35e-3)" "unprognostic (1.29e-3)" "unprognostic (1.23e-2)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "unprognostic (6.17e-3)" "unprognostic (5.02e-2)" "prognostic unfavorable (3.91e-4)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (3.58e-2)" "unprognostic (2.07e-2)" 14.9 15.4 3.5 18.9 3.9 36.9 11.3 5.0 4.2 8.9 7.5 10.2 7.0 10.2 5.3 10.7 9.4 16.8 8.3 3.6 4.5 23.7 7.8 94.1 18.2 4.3 3.4 7.3 8.4 6.1 5.9 20.1 3.7 9.1 9.4 4.3 11.1 7.2 4.7 9.0 9.3 12.6 3.2 11.4 15.7 4.9 4.7 9.3 7.4 5.4 10.5 37.2 7.9 5.5 10.6 20.5 7.4 2.3 93.4 21.4 40.4 77.2 532.4 76.2 118.3 6.9 19.8 1.9 8.5 128.2 29.4 15.5 1.9 32.2 104.8 11.3 6.2 2.6 17.5 27.2 43.1 3.0 5.5 25.5 14.0 26.8 28.7 65.1 41.5 2.4 9.5 3.6 20.0 8.3 1.8 9.0 5.1 26.3 4.9 3.4 5.4 1.9 80.9 49.4 1.4 1.6 42.8 4.8 20.5 20.3 14.9 11.7 25.3 53.3 9.5 9.3 14.2 10.7 5.3 1.4 17.9 26.8 14.2 10.2 9.0 6.0 1.6 10.2 2.0 2.7 1.3 1.8 3.1 1.4 0.9 1.1 8.6 3.3 5.8 0.8 1.9 2.8 3.5 3.9 5.0 4.2 3.6 4.5 4.3 3.4 3.7 3.2 4.7 5.5 17.2 54.5 321.8 4.9 10.7 20.9 21.5 42.4 28.5 1.6 12.8 8.0 4.3 10.0 25.2 29.5 0.0 28.1 5.0 1.3 1.9 11.4 145.0 12.7 30.8 16.5 0.0 11.3 0.5 21.4 30.9 30.5 10.2 15.6 24.1 3.2 10.0 2.0 60.6 0.0 4.7 1.6 14.2 40.5 31.1 80.6 14.0 51.9 8.8 3.7 24.6 3.2 5.2 10.1 0.6 21.7 0.3 10.5 30.9 34.2 0.3 23.4 7.4 0.2 13.1 14.4 9.9 1.2 4.5 3.2 6.1 22.0 6.4 7.3 1.2 22.1 DSEL "C18orf4, DE-epi2, FLJ11477, NCAG1" ENSG00000171451 "Dermatan sulfate epimerase like" Q8IZU8 18 67506587-67516720 "Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 86.4;Extravillous trophoblasts: 72.5;Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 104.2;Theca cells: 83.9" "Cancer enhanced" "Detected in many" "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.7;BJ hTERT+: 43.0;fHDF/TERT166: 38.9;LHCN-M2: 92.1;U-138 MG: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060942 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA060942: AB_2684392" "unprognostic (2.49e-1)" "unprognostic (5.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.19e-5)" "unprognostic (1.56e-1)" "unprognostic (2.71e-1)" "unprognostic (2.40e-3)" "unprognostic (7.11e-2)" "unprognostic (4.91e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.47e-1)" "unprognostic (7.95e-3)" "unprognostic (3.25e-2)" "unprognostic (1.24e-1)" "unprognostic (9.70e-3)" "unprognostic (1.16e-4)" 4.0 1.3 5.1 1.3 8.5 0.3 2.6 7.3 4.7 5.1 0.7 2.2 0.6 2.6 1.6 1.1 3.3 4.0 2.2 5.1 6.4 4.3 3.5 2.7 0.5 9.5 7.4 3.6 1.5 3.2 0.3 6.1 8.8 2.0 1.3 0.8 0.8 2.1 0.7 1.2 1.1 3.6 5.9 2.0 1.2 1.3 7.0 0.8 1.0 1.8 0.3 1.7 1.4 11.7 0.0 0.3 8.7 0.1 16.5 24.3 0.9 70.7 43.0 19.2 8.3 0.1 0.2 0.0 0.1 38.9 4.7 0.4 1.7 3.5 18.5 0.0 0.1 0.0 8.5 0.1 14.6 0.0 0.1 25.3 5.1 11.7 26.0 6.8 3.8 0.0 0.0 1.1 92.1 0.0 0.0 0.0 1.3 0.0 3.7 0.8 19.3 0.1 8.7 0.1 3.1 4.0 4.8 0.2 0.0 3.7 0.1 0.0 6.2 95.6 2.4 6.2 8.6 0.3 0.0 0.0 20.0 0.0 8.1 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 5.1 8.5 7.3 4.7 5.1 6.4 9.5 7.4 8.8 5.9 7.0 11.7 15.9 6.4 16.2 3.3 2.6 11.6 9.9 8.6 19.4 10.1 14.5 12.3 13.3 47.1 5.2 11.0 4.2 2.8 1.4 1.0 0.0 9.7 1.8 3.9 86.4 10.9 6.6 0.0 10.3 2.3 72.5 44.3 8.2 4.2 4.5 9.5 13.2 15.6 2.6 3.3 25.5 1.1 0.0 2.2 9.3 1.7 24.5 3.5 7.2 2.8 0.0 12.6 1.0 112.6 104.2 6.6 0.1 36.9 0.3 8.5 0.4 26.4 1.3 4.2 13.1 43.3 20.9 31.6 21.9 7.1 13.2 8.9 4.9 83.9 0.7 5.2 DUSP14 "MKP-L, MKP6" ENSG00000276023 "Dual specificity phosphatase 14" O95147 17 37489891-37513501 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 44.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 179.7;Basal prostatic cells: 239.3;Cytotrophoblasts: 162.8;Endometrial ciliated cells: 146.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HBF TERT88: 36.4;SuSa: 24.9;WM-115: 37.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019911 Approved Approved Nucleoplasm,Cytosol NA Yes 79000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "HPA019911: AB_1847888" "unprognostic (1.32e-1)" "unprognostic (3.06e-1)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (4.60e-1)" "unprognostic (3.22e-2)" "unprognostic (3.43e-3)" "unprognostic (2.02e-3)" "unprognostic (2.18e-1)" "unprognostic (2.59e-1)" "unprognostic (7.02e-3)" "unprognostic (3.81e-1)" "prognostic unfavorable (6.97e-9)" "unprognostic (7.93e-2)" "unprognostic (1.97e-1)" "unprognostic (1.73e-1)" "unprognostic (1.41e-3)" 15.3 14.2 10.9 1.3 11.2 0.3 12.4 11.2 17.0 12.8 10.9 10.3 0.0 9.5 5.5 17.4 7.5 1.2 14.1 11.0 10.9 8.7 15.2 8.6 0.4 11.9 11.1 5.6 6.6 1.0 14.5 0.9 10.6 6.4 1.0 9.9 13.1 0.3 11.0 44.1 5.5 0.8 10.4 2.8 7.6 13.7 10.8 4.4 23.1 4.4 2.7 7.2 17.1 10.7 2.6 0.2 4.9 2.1 0.1 0.6 2.1 10.4 7.8 14.3 15.6 1.2 17.9 0.2 0.9 7.6 0.2 2.8 0.2 6.1 36.4 0.2 0.7 0.0 1.6 6.2 1.5 0.5 3.0 8.5 5.5 4.8 2.5 10.2 0.3 0.2 0.6 3.1 11.4 0.4 9.7 1.7 0.3 3.8 0.0 2.5 0.6 2.5 17.5 2.4 1.9 0.3 0.5 17.6 4.1 24.9 0.8 3.9 1.4 10.8 5.8 0.1 5.8 0.1 0.3 0.1 0.1 0.0 37.5 1.1 0.0 0.7 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.7 1.6 0.0 0.2 0.0 0.0 0.2 10.9 11.2 11.2 17.0 11.0 10.9 11.9 11.1 10.6 10.4 10.8 10.7 15.0 6.4 5.4 2.9 8.3 179.7 239.3 74.8 129.1 6.8 42.6 46.0 15.0 4.3 39.6 7.3 8.4 162.8 16.6 0.3 29.4 34.8 36.4 146.9 18.5 21.7 2.4 11.4 12.0 15.1 82.1 30.2 3.1 85.3 87.0 10.6 14.6 15.7 19.7 15.2 5.3 1.2 36.7 2.8 34.8 52.5 13.7 5.9 62.2 4.7 25.3 16.1 15.5 3.0 3.3 74.8 2.9 6.0 9.9 64.9 0.1 16.9 61.3 24.5 0.0 13.2 45.2 26.0 33.4 44.0 92.6 67.9 18.2 26.3 1.1 67.0 E2F7 ENSG00000165891 "E2F transcription factor 7" Q96AV8 12 77021248-77065569 "Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;lymphoid tissue: 8.3" "Cell type enhanced" "Detected in many" "Early spermatids: 46.9;Endometrial ciliated cells: 17.2;Late spermatids: 70.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "midbrain: 5.8;pons: 6.4;thalamus: 11.3" HPA064866 Supported "Nuclear speckles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA064866: AB_2685374" "unprognostic (1.21e-1)" "unprognostic (8.92e-2)" "unprognostic (7.39e-2)" "unprognostic (7.27e-2)" "unprognostic (1.54e-1)" "unprognostic (3.80e-2)" "unprognostic (6.14e-5)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (3.57e-2)" "unprognostic (5.67e-5)" "unprognostic (1.42e-1)" "unprognostic (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.00e-1)" "unprognostic (2.51e-1)" 0.2 0.1 0.2 1.1 0.2 5.0 0.2 0.0 0.3 0.3 0.3 0.9 0.7 0.2 0.0 1.4 0.6 0.7 0.2 0.2 0.2 0.1 0.2 0.3 1.5 0.7 0.8 0.1 0.2 0.1 0.5 1.0 0.4 0.2 1.5 0.2 0.2 0.1 0.0 1.1 0.8 0.3 0.6 0.3 0.6 2.9 0.2 8.3 0.1 0.1 1.6 0.6 0.5 0.2 20.1 9.4 25.7 10.1 0.8 2.5 31.1 27.6 29.8 14.2 17.0 12.8 6.6 11.2 5.4 5.5 29.5 15.1 15.5 29.8 27.1 4.4 10.4 9.8 27.3 7.3 5.9 8.5 8.8 0.8 7.7 37.4 22.9 8.3 14.2 19.0 10.4 8.9 29.5 10.1 31.9 0.1 18.1 6.7 21.9 23.0 22.2 6.2 3.5 16.8 16.3 10.7 22.9 7.9 6.5 10.9 12.6 8.7 39.3 53.5 26.8 23.0 36.7 9.5 5.8 7.1 19.3 3.8 34.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.4 0.0 0.2 0.2 0.0 0.3 0.2 0.2 0.7 0.8 0.4 0.6 0.2 0.2 0.1 0.0 0.5 2.3 0.5 0.3 1.0 1.4 4.6 0.0 0.6 0.9 2.1 0.0 2.2 0.0 0.0 1.8 0.4 1.5 0.0 0.3 46.9 17.2 0.8 1.5 0.0 7.4 0.4 1.1 3.1 0.8 6.1 3.1 4.5 6.3 0.0 0.0 0.9 0.0 0.2 1.2 2.0 0.3 1.2 70.2 0.3 1.3 0.0 3.7 0.0 1.6 0.0 0.5 0.0 12.0 0.1 0.7 6.9 1.7 0.0 0.0 3.1 0.1 0.0 0.0 1.2 1.2 2.1 6.3 0.6 0.3 0.8 0.4 2.1 4.3 ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 113.3;Fibroblasts: 118.6;Melanocytes: 74.7;Pancreatic endocrine cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 402.1;BJ hTERT+: 293.1;fHDF/TERT166: 279.6;hTEC/SVTERT24-B: 195.6;LHCN-M2: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" 49.3 15.4 7.6 11.8 8.5 0.8 27.1 7.3 14.7 293.8 6.1 17.7 9.4 51.2 484.1 1370.5 20.1 76.5 81.3 8.1 8.3 15.9 61.2 26.3 1.2 17.4 8.9 8.9 4.1 3.5 12.7 44.6 15.4 15.5 18.1 0.9 223.9 14.0 7.0 70.0 12.4 32.6 8.9 11.5 12.4 2.7 9.4 1.3 11.1 7.8 135.0 24.4 360.1 10.7 35.4 3.5 12.6 0.2 73.9 402.1 11.4 126.9 293.1 76.2 99.5 1.9 19.1 0.6 1.3 279.6 8.8 71.5 0.2 15.0 79.3 0.6 0.7 5.7 4.1 0.7 20.4 0.3 125.5 35.7 0.9 195.6 7.2 112.8 21.3 0.7 27.7 0.8 215.2 0.1 0.4 4.2 1.4 147.8 4.1 2.0 92.7 0.5 2.8 0.1 0.8 0.4 28.8 0.9 106.4 5.8 0.3 34.0 5.8 159.3 23.9 18.3 27.9 0.5 1.1 1.5 84.6 11.7 22.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.6 8.5 7.3 14.7 8.1 8.3 17.4 8.9 15.4 8.9 9.4 10.7 9.1 0.0 1.1 2.9 0.6 14.7 1.9 6.9 0.0 0.7 0.5 0.6 1.8 7.2 7.9 3.7 0.0 2.2 0.6 1.0 0.0 6.2 0.3 3.1 113.3 15.7 0.0 0.0 12.1 4.3 40.9 118.6 7.7 2.5 10.2 1.0 42.5 1.0 17.0 1.7 10.9 1.4 18.3 2.2 22.8 0.3 9.9 10.8 74.7 2.8 0.1 0.5 0.0 1.0 4.4 70.2 1.1 22.2 0.4 1.5 0.1 0.1 0.4 1.2 13.1 4.1 32.3 0.7 0.6 28.1 19.0 10.9 2.1 5.0 0.5 6.9 EFEMP2 "FBLN4, UPH1" ENSG00000172638 "EGF containing fibulin extracellular matrix protein 2" O95967 11 65866441-65873592 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 122.8;Leydig cells: 93.5;Muller glia cells: 84.8;Peritubular cells: 107.2;Smooth muscle cells: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 125.8;BJ hTERT+: 159.7;fHDF/TERT166: 232.6;HSkMC: 155.3;hTERT-RPE1: 159.1;LHCN-M2: 134.5;U-138 MG: 114.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023270 Approved "Secreted to extracellular matrix" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA023270: AB_1848019" "unprognostic (3.13e-1)" "unprognostic (2.15e-3)" "unprognostic (3.23e-2)" "unprognostic (5.11e-2)" "unprognostic (8.57e-3)" "unprognostic (1.50e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.89e-2)" "unprognostic (9.12e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (8.33e-3)" "unprognostic (6.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.58e-2)" 38.4 18.0 19.8 13.8 21.1 2.8 29.5 18.8 26.7 46.6 22.1 39.6 9.3 55.2 8.3 12.8 35.8 33.5 61.6 19.1 20.4 26.8 7.0 32.1 9.1 24.9 20.0 47.0 19.9 26.8 15.2 22.4 21.4 31.1 6.5 5.9 17.4 35.2 21.2 14.9 16.2 32.3 20.3 16.1 20.6 8.2 21.4 5.6 39.1 22.0 5.0 33.1 30.7 19.1 0.5 0.2 2.1 47.3 54.3 108.0 0.8 125.8 159.7 48.1 44.8 0.0 4.3 0.7 9.3 232.6 0.7 0.9 0.0 1.3 12.1 5.4 0.1 1.1 3.2 8.0 89.1 0.0 0.4 155.3 0.4 18.9 1.0 159.1 28.5 1.0 0.3 8.0 134.5 0.4 0.2 20.7 1.6 0.2 0.6 0.4 0.3 3.2 1.6 0.6 0.7 14.1 0.2 1.3 1.5 6.6 1.5 10.0 64.6 114.2 24.7 52.6 0.6 10.9 0.7 0.3 42.6 0.8 19.7 0.0 0.1 0.5 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.7 0.0 0.0 0.0 0.2 19.8 21.1 18.8 26.7 19.1 20.4 24.9 20.0 21.4 20.3 21.4 19.1 30.8 35.3 7.4 29.0 1.5 13.5 38.9 33.9 8.6 7.7 10.2 27.6 46.0 15.7 11.4 18.4 0.0 2.4 2.3 0.3 7.9 28.7 15.6 3.4 57.1 27.9 0.0 0.4 1.1 0.2 3.9 122.8 2.6 4.1 0.0 74.3 42.8 1.8 9.8 6.7 2.9 0.3 4.1 3.5 19.1 33.3 93.5 3.0 24.9 9.4 0.7 84.8 2.1 9.5 1.6 2.6 0.1 107.2 1.4 30.1 0.2 21.2 9.0 4.8 39.5 41.1 113.2 35.9 3.3 1.1 10.1 5.9 2.4 78.5 0.3 14.2 EGFL6 MAEG ENSG00000198759 "EGF like domain multiple 6" Q8IUX8 X 13569601-13633575 "Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "placenta: 645.2" "Cell type enriched" "Detected in many" 8 "Fibroblasts: 214.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 4.3;NTERA-2: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001838 Enhanced "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA001838: AB_2666457" "unprognostic (1.66e-1)" "unprognostic (1.32e-2)" "unprognostic (9.15e-3)" "unprognostic (3.76e-3)" "unprognostic (1.77e-2)" "prognostic favorable (9.73e-4)" "unprognostic (4.13e-3)" "unprognostic (1.37e-1)" "unprognostic (5.19e-3)" "prognostic favorable (4.95e-4)" "unprognostic (2.39e-3)" "unprognostic (1.81e-1)" "unprognostic (1.14e-9)" "unprognostic (7.10e-2)" "unprognostic (3.21e-2)" "unprognostic (1.70e-1)" "unprognostic (1.82e-3)" 20.1 0.0 0.4 0.6 0.5 0.0 3.2 0.1 0.3 1.0 0.1 0.2 0.5 1.8 0.0 4.3 2.2 1.1 0.3 0.3 1.2 0.7 0.0 25.6 0.3 0.9 1.3 0.3 1.2 0.6 2.6 645.2 0.4 1.1 0.3 2.3 0.4 0.1 0.0 0.5 0.4 0.5 1.6 0.3 1.3 0.3 0.4 0.2 0.3 1.6 1.6 10.7 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.1 0.3 0.3 1.2 0.9 1.3 0.4 1.6 0.4 0.2 1.3 0.0 2.0 0.0 0.0 1.0 1.2 22.0 1.2 6.3 0.1 0.5 0.4 0.0 11.9 0.0 0.0 12.4 0.0 0.5 0.0 0.0 0.3 4.2 5.6 6.0 0.0 0.0 0.3 0.0 9.8 214.7 0.0 3.7 0.0 0.0 0.0 0.0 17.3 0.0 2.0 0.1 4.1 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.4 1.0 0.0 0.0 23.9 0.1 1.1 14.9 0.4 26.4 0.9 4.9 0.1 3.7 EGFLAM "AGRINL, AGRNL, FLJ39155, PIKA" ENSG00000164318 "EGF like, fibronectin type III and laminin G domains" Q63HQ2 5 38258409-38465480 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 121.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 120.9;Early spermatids: 50.7;Late spermatids: 49.1;Leydig cells: 155.4;Sertoli cells: 85.5;Smooth muscle cells: 70.9" "Cancer enhanced" "Detected in all" "testis cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 10.2;HBEC3-KT: 12.6;hTERT-HME1: 16.4;HUVEC TERT2: 16.1;LHCN-M2: 37.0;U-2 OS: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066577 Approved "Secreted - unknown location" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA066577: " "unprognostic (2.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.38e-3)" "unprognostic (1.08e-2)" "unprognostic (3.63e-3)" "unprognostic (6.31e-2)" "unprognostic (2.83e-1)" "unprognostic (2.08e-2)" "unprognostic (1.71e-3)" "unprognostic (1.12e-1)" "unprognostic (5.80e-2)" "prognostic unfavorable (4.47e-5)" "unprognostic (7.02e-6)" "unprognostic (2.60e-1)" "unprognostic (9.90e-2)" "unprognostic (1.04e-2)" 41.7 19.8 2.0 2.8 2.5 0.2 47.1 1.9 2.3 15.6 3.5 6.1 1.9 5.6 6.8 4.0 8.2 4.9 26.2 1.5 2.4 6.9 4.7 2.9 14.2 3.2 4.2 23.7 3.1 4.0 5.8 51.6 3.6 14.2 3.2 66.7 6.9 20.6 72.0 5.9 4.7 6.7 1.6 9.8 3.4 15.0 3.6 20.4 9.0 121.2 9.1 7.7 13.0 2.5 3.2 0.0 6.5 0.2 0.8 0.2 0.0 2.9 0.0 0.5 0.1 0.0 0.0 0.1 10.2 0.1 0.1 0.0 0.0 12.6 0.0 0.0 1.6 0.0 6.1 0.0 2.8 0.0 0.1 5.4 0.0 0.1 16.4 0.0 16.1 0.0 0.0 0.0 37.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.3 3.9 0.0 3.7 0.1 1.3 0.0 0.2 0.0 0.1 15.6 0.6 0.2 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.5 1.9 2.3 1.5 2.4 3.2 4.2 3.6 1.6 3.6 2.5 11.4 0.0 0.0 0.3 0.0 2.7 0.3 0.0 0.0 1.3 2.4 9.8 2.6 0.0 0.0 0.0 120.9 0.3 0.4 0.0 3.9 0.5 50.7 0.2 3.2 5.4 0.0 0.0 0.6 1.0 0.5 17.8 0.0 0.3 0.0 1.6 1.4 0.0 0.7 0.0 0.9 0.0 0.0 0.0 4.2 49.1 155.4 0.6 5.4 1.9 0.0 3.4 0.0 1.0 0.1 1.3 0.0 30.9 0.0 0.2 0.0 6.5 0.0 33.1 85.5 22.0 70.9 9.8 3.3 0.3 2.0 0.5 0.4 23.5 0.0 0.3 EHD2 PAST2 ENSG00000024422 "EH domain containing 2" Q9NZN4 19 47713422-47743134 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 161.9;Leydig cells: 99.1;Peritubular cells: 107.2;Sertoli cells: 236.7;Smooth muscle cells: 139.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 312.2;BJ: 238.5;fHDF/TERT166: 258.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047394, HPA049890, HPA049986, HPA066751" Approved Supported "Plasma membrane" NA NA 1500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "HPA047394: AB_2680026, HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713" "unprognostic (1.50e-1)" "unprognostic (2.11e-2)" "unprognostic (3.16e-3)" "unprognostic (1.54e-1)" "unprognostic (3.33e-2)" "unprognostic (5.42e-3)" "unprognostic (3.36e-2)" "unprognostic (1.33e-2)" "unprognostic (2.70e-3)" "prognostic unfavorable (8.75e-4)" "unprognostic (5.49e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (6.59e-3)" "unprognostic (6.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.06e-3)" 195.0 59.9 18.4 32.8 17.6 0.4 133.9 16.5 21.2 110.3 11.9 116.1 14.3 119.9 13.2 53.5 75.4 31.2 85.9 15.9 17.1 24.4 14.4 102.8 9.1 23.3 19.3 68.3 28.2 6.2 12.6 50.3 20.0 62.2 14.7 3.0 34.2 51.1 39.6 54.7 54.5 79.6 17.2 40.3 56.3 11.2 24.1 5.1 49.5 28.2 8.3 112.3 88.8 15.8 62.7 142.7 0.1 1.7 312.2 236.0 0.2 238.5 114.0 86.0 70.0 9.3 31.2 0.0 0.3 258.6 20.3 78.1 1.5 126.5 51.9 0.1 0.8 8.4 78.4 0.7 197.0 0.0 16.6 230.1 109.5 72.5 70.6 113.7 168.4 0.7 26.6 0.2 91.7 11.4 13.3 0.7 1.8 9.2 25.9 1.4 10.0 0.2 69.5 2.9 0.1 0.8 212.5 8.2 6.2 19.1 20.2 4.3 192.6 128.0 27.8 112.5 52.2 0.2 0.2 0.2 119.3 3.3 27.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 18.4 17.6 16.5 21.2 15.9 17.1 23.3 19.3 20.0 17.2 24.1 15.8 161.9 60.9 20.6 10.7 0.3 20.3 29.4 31.0 12.5 5.5 7.3 10.8 11.6 10.0 22.5 5.5 0.0 1.1 0.8 0.1 0.0 21.2 0.6 3.4 60.5 75.4 0.0 8.6 4.0 14.1 1.6 55.8 5.1 4.5 2.5 24.7 48.9 3.1 1.9 0.0 0.9 0.0 2.0 1.3 8.8 4.3 99.1 1.6 8.8 7.5 0.6 1.8 0.0 3.5 0.3 31.1 0.0 107.2 0.1 28.8 0.0 0.1 5.5 0.8 236.7 24.8 139.4 0.9 3.0 15.8 13.5 1.5 1.5 27.2 0.0 33.4 EHD3 PAST3 ENSG00000013016 "EH domain containing 3" Q9NZN3 2 31234152-31269451 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.7;esophagus: 43.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 24.3;Hepatic stellate cells: 120.3;Syncytiotrophoblasts: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 20.8;naive B-cell: 5.6" "Lineage enriched" "Detected in many" 7 "B-cells: 20.8" "Cell line enhanced" "Detected in many" "BJ: 79.7;BJ hTERT+: 192.2;HEL: 77.4;U-266/70: 48.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA066751" Approved Approved "Plasma membrane" NA NA 15000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713" "unprognostic (3.44e-1)" "unprognostic (8.88e-2)" "unprognostic (2.21e-1)" "unprognostic (3.79e-2)" "unprognostic (3.70e-2)" "unprognostic (1.89e-1)" "unprognostic (5.49e-2)" "unprognostic (1.21e-1)" "unprognostic (3.74e-2)" "unprognostic (9.72e-2)" "unprognostic (9.92e-3)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (4.88e-3)" "unprognostic (9.41e-2)" "unprognostic (4.79e-3)" "unprognostic (4.92e-3)" 2.5 9.1 20.5 5.9 29.5 1.9 3.2 10.5 38.7 5.5 1.1 2.5 1.6 4.4 3.0 43.9 4.5 3.4 15.9 29.5 18.5 20.0 11.0 5.7 6.8 11.7 17.8 2.5 1.3 21.1 9.1 11.7 13.9 5.5 1.7 9.0 5.9 4.4 2.3 3.1 3.7 4.6 9.6 7.3 2.2 1.3 31.1 2.7 3.2 5.1 11.1 6.6 6.0 26.2 1.8 8.4 4.5 3.9 7.5 11.3 0.7 79.7 192.2 7.5 6.9 0.0 0.9 0.6 2.9 26.0 6.5 0.8 0.2 5.2 5.3 3.2 7.1 77.4 0.4 0.0 25.7 0.0 0.2 18.1 2.3 7.3 3.0 20.0 0.1 0.2 0.3 0.4 5.6 12.6 1.0 0.1 17.7 0.0 4.3 2.8 0.3 1.8 5.8 8.9 2.2 12.1 0.8 1.3 0.0 14.1 1.2 0.0 0.0 5.8 5.4 0.3 6.5 48.7 6.5 0.1 14.8 0.0 12.4 0.6 0.5 0.5 2.1 1.0 1.1 20.8 1.0 1.4 0.5 5.6 0.9 0.5 1.2 0.8 2.8 0.0 0.5 10.2 20.5 29.5 10.5 38.7 29.5 18.5 11.7 17.8 13.9 9.6 31.1 26.2 1.9 0.0 0.0 2.6 16.2 0.8 1.8 1.7 10.2 9.7 0.6 6.2 24.3 5.7 0.9 0.0 0.0 4.1 0.6 0.0 0.0 0.5 0.1 0.7 2.3 8.4 1.8 6.1 17.1 0.2 8.4 3.3 1.1 0.5 0.0 0.4 120.3 5.0 1.7 0.0 11.1 0.1 0.0 16.1 0.4 0.0 1.2 5.9 0.0 4.7 1.1 9.0 0.0 22.6 5.4 0.2 0.1 3.0 5.8 2.6 0.0 0.2 0.4 5.9 19.7 3.0 7.0 0.6 2.7 10.7 0.9 43.9 1.4 0.7 0.1 4.7 EMC1 KIAA0090 ENSG00000127463 "ER membrane protein complex subunit 1" Q8N766 1 19215660-19251527 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 63.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048904 Approved NA NA 14000 "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA048904: AB_2680552" "unprognostic (9.46e-3)" "unprognostic (1.91e-3)" "unprognostic (1.75e-2)" "unprognostic (4.11e-3)" "unprognostic (2.05e-1)" "unprognostic (5.31e-3)" "prognostic unfavorable (8.56e-6)" "unprognostic (5.98e-2)" "unprognostic (1.69e-1)" "unprognostic (1.08e-1)" "unprognostic (4.96e-2)" "unprognostic (2.50e-1)" "unprognostic (3.02e-2)" "unprognostic (1.61e-1)" "unprognostic (1.54e-1)" "unprognostic (6.19e-2)" "prognostic unfavorable (1.43e-4)" 15.4 11.2 10.1 11.7 11.6 9.2 11.1 11.7 14.0 12.2 2.1 12.8 8.7 12.2 13.1 10.7 12.0 8.2 12.5 11.8 16.0 10.8 15.5 12.0 9.0 8.3 9.5 14.1 10.6 16.3 10.0 24.0 11.3 13.2 14.1 51.9 10.7 11.0 19.9 11.6 9.1 18.9 5.1 9.7 11.0 13.1 12.4 9.4 14.0 14.3 10.5 11.7 9.8 8.8 41.1 36.5 40.3 105.4 63.6 49.3 78.3 65.1 60.8 88.3 86.8 38.4 92.5 36.5 84.1 100.6 57.1 45.4 56.7 73.0 102.1 31.0 29.6 44.0 46.3 45.5 46.2 56.9 50.7 52.7 46.4 104.6 86.2 82.2 75.6 31.2 55.1 53.7 69.1 23.5 23.3 27.9 24.4 47.2 33.9 34.4 49.7 64.2 35.8 18.8 49.6 33.9 71.5 37.0 54.6 47.2 40.5 35.3 67.3 79.5 51.7 61.2 75.2 29.7 67.0 46.3 75.4 73.5 108.4 5.2 12.7 3.1 8.1 9.6 9.0 6.2 8.1 9.2 12.6 7.0 8.0 8.0 0.5 21.7 12.8 6.1 6.2 9.1 10.1 11.6 11.7 14.0 11.8 16.0 8.3 9.5 11.3 5.1 12.4 8.8 13.0 16.0 14.6 8.1 12.4 11.6 10.1 16.9 8.0 20.3 11.2 11.7 15.7 11.5 10.5 22.0 10.4 40.4 9.9 11.4 0.0 14.3 1.2 10.0 18.0 16.1 19.7 6.9 12.9 8.5 41.0 19.2 9.7 15.0 8.2 23.2 14.3 25.6 19.4 15.2 14.5 11.4 14.2 12.3 7.3 2.6 14.9 11.5 10.6 8.4 12.0 19.0 4.1 15.1 10.9 10.6 9.4 14.3 14.5 10.3 6.4 9.0 7.8 63.4 6.6 20.1 13.5 12.9 19.3 13.0 9.2 36.0 8.9 18.6 12.7 6.7 ENTPD7 "FLJ30978, LALP1" ENSG00000198018 "Ectonucleoside triphosphate diphosphohydrolase 7" Q9NQZ7 10 99659509-99711241 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 14.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 17.5;Urothelial cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014351 Uncertain Approved Nucleoplasm NA NA 65000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA014351: AB_1848183" "unprognostic (1.82e-1)" "unprognostic (7.26e-2)" "unprognostic (1.11e-2)" "unprognostic (6.01e-3)" "unprognostic (6.22e-2)" "unprognostic (3.32e-3)" "unprognostic (9.35e-2)" "unprognostic (3.77e-3)" "unprognostic (3.83e-2)" "unprognostic (1.74e-1)" "unprognostic (1.66e-2)" "unprognostic (1.39e-1)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "unprognostic (1.22e-1)" "unprognostic (2.99e-2)" "unprognostic (3.39e-1)" 1.8 3.7 0.4 4.2 0.5 7.0 2.2 1.7 0.7 3.2 3.9 3.7 14.6 2.1 2.2 4.4 1.8 4.5 1.3 0.7 0.2 2.7 6.3 1.9 2.2 0.3 0.4 1.0 6.9 2.9 1.7 6.5 0.2 2.7 3.8 2.7 2.9 2.3 0.5 2.9 14.6 2.7 0.3 2.1 3.9 1.4 0.3 1.6 2.2 0.4 2.7 10.2 2.6 0.5 5.4 5.9 8.0 14.4 4.0 3.6 8.4 10.0 19.1 11.4 9.2 11.1 5.2 4.8 5.4 14.0 3.6 13.6 6.0 4.0 9.6 2.3 5.6 4.0 4.4 11.2 5.8 13.4 7.8 3.5 6.7 14.1 15.3 14.1 11.8 5.1 6.1 4.7 4.8 4.6 2.6 3.9 4.7 6.0 2.4 0.3 6.2 2.4 15.8 16.7 3.4 6.9 6.7 2.7 9.5 5.4 7.1 5.9 8.5 11.0 6.2 7.0 8.4 4.7 7.3 4.1 11.0 4.4 2.7 0.3 0.6 0.9 0.6 0.7 0.5 0.2 0.3 0.5 1.3 0.1 0.4 0.3 0.5 0.8 0.4 2.3 0.2 0.3 0.4 0.5 1.7 0.7 0.7 0.2 0.3 0.4 0.2 0.3 0.3 0.5 1.2 0.0 0.0 2.9 1.3 8.2 17.5 4.6 10.8 0.7 2.0 1.1 0.8 1.5 2.2 5.5 2.1 6.3 3.2 3.7 0.0 2.3 1.5 6.0 2.8 1.7 5.4 1.3 9.5 5.0 5.3 2.4 9.2 5.3 0.0 0.7 0.7 4.7 1.9 0.0 7.9 4.2 0.0 0.6 2.7 2.7 0.9 2.6 0.0 6.5 4.9 0.4 0.0 10.1 3.2 4.5 3.1 0.7 7.6 2.6 11.4 1.3 3.6 1.9 0.0 1.1 1.7 1.2 0.8 6.9 7.4 5.1 1.2 3.9 2.4 23.6 EPG5 "hEPG5, KIAA1632" ENSG00000152223 "Ectopic P-granules autophagy protein 5 homolog" Q9HCE0 18 45847609-45967329 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 53.1;Oligodendrocytes: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "LHCN-M2: 55.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031689 Uncertain Approved "Nuclear speckles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "HPA031689: AB_10609997" "unprognostic (3.43e-1)" "unprognostic (1.20e-1)" "unprognostic (8.11e-2)" "unprognostic (6.84e-2)" "unprognostic (2.20e-2)" "unprognostic (4.59e-2)" "unprognostic (5.58e-2)" "unprognostic (1.02e-1)" "unprognostic (4.66e-1)" "unprognostic (4.87e-1)" "unprognostic (1.15e-2)" "unprognostic (7.50e-2)" "prognostic favorable (4.04e-5)" "unprognostic (5.71e-2)" "unprognostic (1.35e-1)" "unprognostic (4.05e-1)" "unprognostic (1.18e-1)" 6.6 6.8 5.8 4.4 6.0 13.8 6.8 6.3 6.2 7.1 5.1 5.8 3.2 6.1 5.8 7.1 6.0 3.2 8.4 6.2 5.3 6.6 6.0 8.8 5.7 5.1 8.1 8.9 6.3 6.9 7.6 4.5 5.3 5.9 4.0 8.6 6.0 3.7 8.6 10.1 6.0 4.1 4.5 9.5 5.6 4.8 5.8 8.4 9.3 6.7 5.9 5.4 6.6 6.3 5.3 4.1 4.1 3.0 13.8 16.6 4.1 33.2 13.7 18.7 19.4 1.2 3.9 5.4 2.0 25.0 22.5 4.9 5.5 6.6 23.7 4.5 2.3 4.2 4.7 4.2 13.1 7.2 10.4 11.2 6.0 20.6 14.0 16.5 9.4 4.7 3.7 2.8 55.8 3.7 3.2 6.9 2.0 1.9 2.5 3.0 5.1 3.8 8.8 7.3 4.4 3.4 5.9 2.4 7.0 5.8 3.4 5.1 23.0 23.2 4.9 3.4 9.2 5.7 4.3 3.0 9.9 6.2 7.7 0.4 0.7 0.7 1.5 0.7 1.4 0.4 0.9 0.8 0.5 0.6 0.7 0.9 0.8 0.4 0.6 0.6 0.5 0.3 5.8 6.0 6.3 6.2 6.2 5.3 5.1 8.1 5.3 4.5 5.8 6.3 8.8 19.2 10.5 24.5 9.0 10.3 4.6 6.8 8.0 16.7 11.9 8.3 17.1 10.0 7.4 11.0 25.0 7.6 15.7 5.8 1.9 6.5 4.6 9.0 9.8 9.3 8.3 11.4 53.1 3.6 4.4 7.8 6.1 16.9 7.0 14.4 13.6 10.3 12.2 13.5 46.5 6.9 6.1 16.0 6.2 3.0 12.5 11.5 14.2 40.3 16.6 6.5 27.8 40.2 51.4 7.8 6.5 11.7 10.0 9.1 6.2 8.3 10.5 17.4 13.1 9.8 6.7 8.4 7.1 5.9 13.2 9.0 15.4 9.8 6.5 9.4 ERCC2 "EM9, MAG, MGC102762, MGC126218, MGC126219, XPD" ENSG00000104884 "ERCC excision repair 2, TFIIH core complex helicase subunit" P18074 19 45349837-45370918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 34.1;Spermatocytes: 30.5;Theca cells: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005375, HPA038057, HPA069266" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "CAB005375: AB_2100152, HPA038057: AB_2675810, HPA069266: AB_2686104" "unprognostic (1.10e-1)" "unprognostic (5.48e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-3)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (1.06e-1)" "prognostic favorable (3.26e-4)" "unprognostic (3.36e-2)" "unprognostic (2.44e-3)" "unprognostic (1.94e-1)" "unprognostic (5.47e-1)" "unprognostic (8.99e-2)" "unprognostic (3.45e-2)" 6.8 13.0 10.5 6.9 10.3 4.8 6.5 8.4 11.7 7.5 8.4 7.5 4.9 9.7 3.2 6.3 8.0 4.1 7.0 10.8 9.3 7.6 9.0 5.8 5.8 10.6 9.9 7.8 7.7 7.7 9.7 4.5 9.6 6.7 4.0 3.1 7.3 6.7 11.7 7.2 6.6 6.9 8.1 8.1 7.5 13.9 10.1 5.3 8.4 6.3 5.2 7.5 5.9 8.9 28.0 13.3 27.1 38.4 16.3 19.4 15.2 38.8 27.4 50.2 40.2 32.6 18.6 10.0 21.6 39.9 19.1 14.0 19.1 32.9 18.5 24.4 31.8 16.9 26.8 35.4 33.3 27.1 28.4 22.4 5.6 55.8 31.9 28.2 29.1 28.8 41.8 10.9 34.8 14.7 16.1 17.9 12.7 27.2 24.6 30.3 19.4 8.3 14.0 24.9 15.8 17.1 34.2 23.9 13.6 20.6 22.8 35.4 37.9 46.4 25.3 19.9 88.0 24.9 15.8 14.2 13.8 16.4 21.2 0.0 17.2 6.5 9.1 18.0 11.9 9.1 8.9 8.9 21.8 6.5 8.2 8.7 0.5 15.6 14.9 10.4 9.8 12.1 10.5 10.3 8.4 11.7 10.8 9.3 10.6 9.9 9.6 8.1 10.1 8.9 4.2 6.4 3.4 6.2 5.8 6.2 5.5 8.6 4.6 0.0 6.1 4.3 6.7 8.6 8.7 5.5 0.0 10.5 4.1 5.9 13.7 10.7 4.7 3.3 4.5 5.5 7.2 5.5 2.9 8.2 12.1 6.8 6.1 3.8 0.0 34.1 7.9 12.3 11.5 0.0 3.1 8.5 4.1 8.2 4.2 2.8 6.5 6.3 3.6 1.0 4.2 0.0 5.2 5.0 1.4 8.1 3.1 7.9 7.5 4.2 4.1 13.0 7.5 0.0 0.0 3.5 9.9 30.5 13.1 5.1 5.7 4.8 4.7 29.1 8.8 3.2 ERLEC1 "C2orf30, CL25084, ERLECTIN, XTP3-B, XTP3TPB" ENSG00000068912 "Endoplasmic reticulum lectin 1" Q96DZ1 2 53787044-53818819 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 394.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031501, HPA031502, HPA031503" Enhanced "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "HPA031501: AB_10600104, HPA031502: AB_10602174, HPA031503: AB_10670425" "unprognostic (1.27e-2)" "unprognostic (3.36e-3)" "unprognostic (3.17e-1)" "unprognostic (1.97e-3)" "unprognostic (1.08e-2)" "unprognostic (1.86e-1)" "unprognostic (3.27e-3)" "unprognostic (3.79e-1)" "unprognostic (1.29e-1)" "unprognostic (2.95e-2)" "unprognostic (1.82e-1)" "unprognostic (1.92e-1)" "unprognostic (4.71e-2)" "unprognostic (1.47e-1)" "unprognostic (8.13e-2)" "unprognostic (2.33e-2)" "unprognostic (3.92e-2)" 38.4 51.0 30.2 31.3 32.1 33.8 48.7 29.3 41.9 66.4 39.3 45.8 37.7 40.9 93.9 26.1 36.2 41.0 45.2 32.9 39.2 38.1 43.4 44.1 32.4 28.7 31.1 38.0 67.1 57.3 59.4 56.6 31.5 72.8 50.2 54.5 54.0 55.9 32.1 20.1 34.0 38.5 30.1 33.1 55.3 42.4 31.5 28.1 72.5 39.5 41.2 44.7 27.2 34.4 42.1 47.3 44.4 27.4 123.3 111.3 65.5 100.5 109.1 49.0 51.4 31.3 55.7 29.4 94.5 106.3 86.3 29.7 29.2 42.3 62.1 67.0 38.7 36.1 29.1 93.8 84.4 60.2 63.9 70.5 69.4 51.6 83.3 99.4 58.1 28.6 39.0 115.8 73.6 35.3 27.7 48.0 34.1 67.1 30.4 24.9 53.1 82.7 57.7 39.3 26.5 46.3 36.6 79.0 64.6 50.3 38.0 45.9 63.3 53.9 47.2 44.0 60.3 170.1 120.3 16.5 88.2 35.8 64.5 77.0 25.1 30.7 41.4 27.8 45.8 36.8 36.3 39.9 28.0 28.6 33.9 39.0 9.6 45.4 33.3 40.1 36.6 41.5 30.2 32.1 29.3 41.9 32.9 39.2 28.7 31.1 31.5 30.1 31.5 34.4 57.2 89.8 116.7 22.2 86.3 25.1 42.5 88.0 34.1 77.0 76.3 54.6 83.5 52.9 93.5 66.2 31.3 100.2 60.9 43.4 33.2 76.1 168.4 67.7 77.5 63.8 55.1 23.1 24.0 115.7 105.8 99.7 54.6 101.7 74.1 36.6 68.6 81.8 60.1 95.9 28.5 169.7 107.8 39.7 31.5 117.9 88.3 41.7 80.0 17.8 61.7 79.7 72.1 20.6 25.3 90.2 42.8 84.2 394.0 113.4 32.3 51.4 118.2 68.6 52.6 55.6 109.5 146.1 65.3 40.3 33.4 183.6 57.0 48.3 57.1 67.5 ESPNL FLJ42568 ENSG00000144488 "Espin like" Q6ZVH7 2 238100340-238133287 "Predicted intracellular proteins" Hearing Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;intestine: 3.5" "Cell type enhanced" "Detected in some" "B-cells: 1.8;Cardiomyocytes: 2.5;Granulosa cells: 2.0;Muller glia cells: 1.4;Proximal tubular cells: 3.4;Skeletal myocytes: 1.6;Theca cells: 2.2" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 12 "cerebellum: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.8;Daudi: 2.6;fHDF/TERT166: 2.3;HHSteC: 2.6;THP-1: 1.8;U-87 MG: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA055103 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA055103: AB_2682694" "unprognostic (8.04e-2)" "unprognostic (1.29e-1)" "unprognostic (2.34e-2)" "unprognostic (1.18e-3)" "unprognostic (1.51e-2)" "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (3.20e-1)" "unprognostic (1.79e-1)" "unprognostic (2.18e-1)" "unprognostic (2.95e-1)" "unprognostic (2.24e-1)" "unprognostic (3.94e-6)" "unprognostic (3.49e-2)" "unprognostic (8.52e-2)" "unprognostic (1.08e-1)" "unprognostic (5.67e-2)" 0.4 0.3 0.4 0.1 0.2 0.0 0.4 5.0 0.2 0.8 0.9 0.8 0.3 1.0 0.0 0.2 1.5 0.1 0.7 0.4 0.3 0.3 1.6 0.2 0.5 0.2 0.3 2.2 0.3 0.0 2.1 0.1 0.4 0.6 0.0 0.0 0.0 0.8 0.2 0.2 3.5 0.4 0.0 1.1 0.2 0.4 0.2 0.3 1.0 0.0 0.2 0.6 0.4 0.3 0.0 0.0 0.0 1.8 0.3 0.6 0.3 1.0 0.4 0.8 0.8 0.0 0.0 2.6 1.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.9 2.6 0.0 0.5 0.9 0.0 0.1 0.0 0.0 0.0 0.8 0.8 0.0 1.0 0.0 0.0 1.1 0.1 0.0 0.0 0.8 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 5.0 0.2 0.4 0.3 0.2 0.3 0.4 0.0 0.2 0.3 0.1 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.6 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.0 2.0 0.0 0.5 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.3 0.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 1.6 0.3 0.0 0.6 0.0 0.0 0.0 0.4 2.2 0.0 0.0 EVA1A "FAM176A, FLJ13391, TMEM166" ENSG00000115363 "Eva-1 homolog A, regulator of programmed cell death" Q9H8M9 2 75469302-75569722 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 191.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Cytotrophoblasts: 43.3;Hepatocytes: 78.1;Proximal tubular cells: 77.3;Syncytiotrophoblasts: 124.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 85.7;U-138 MG: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008055 Approved Supported "Vesicles,Plasma membrane" NA Yes "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Plasma membrane" "HPA008055: AB_1080308" "unprognostic (2.72e-1)" "unprognostic (2.61e-2)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.60e-2)" "unprognostic (5.02e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.67e-4)" "unprognostic (7.33e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.80e-4)" "unprognostic (8.19e-2)" "unprognostic (4.37e-2)" "unprognostic (2.43e-2)" "unprognostic (9.07e-2)" 1.1 0.5 0.2 1.1 0.9 0.1 3.4 0.6 0.5 9.8 0.2 0.7 1.7 2.8 9.6 0.4 3.7 1.2 1.6 0.2 0.3 20.0 191.6 20.7 0.4 1.1 0.5 0.5 23.8 7.6 1.1 17.3 0.9 0.9 0.7 0.5 8.9 2.2 1.2 2.7 1.8 2.0 0.7 10.8 0.6 2.9 0.8 5.1 1.8 1.6 0.3 0.8 0.8 0.8 1.0 14.5 1.5 0.4 3.1 21.2 1.4 68.0 45.3 59.2 30.1 0.5 1.2 0.1 6.3 85.7 54.2 9.4 1.7 14.4 36.8 0.0 1.1 0.0 2.5 45.7 2.2 0.0 0.1 15.0 8.3 73.2 33.3 59.0 37.2 0.0 0.0 0.0 46.1 0.0 0.1 0.0 3.3 0.2 23.5 7.9 0.1 0.0 32.5 0.5 0.9 1.6 6.2 0.4 53.7 2.2 0.2 0.3 31.0 110.3 46.3 2.0 71.9 0.7 0.1 0.3 62.5 0.0 59.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.6 0.5 0.2 0.3 1.1 0.5 0.9 0.7 0.8 0.8 6.1 41.7 35.4 1.0 0.9 2.8 13.7 14.3 3.4 1.2 11.7 12.3 0.3 1.5 23.0 11.0 0.0 43.3 0.4 0.1 27.4 30.5 12.2 13.3 1.4 4.8 1.8 0.0 1.1 16.1 25.9 4.7 0.0 11.4 0.0 0.0 2.2 78.1 3.5 0.0 0.9 1.1 4.1 0.8 1.2 9.4 0.3 0.6 28.4 2.8 0.1 0.0 0.0 1.5 0.9 9.7 0.0 0.7 0.0 12.3 0.5 77.3 1.7 0.1 0.0 2.2 9.0 2.2 0.9 1.1 0.9 124.8 1.1 0.0 1.6 10.5 EXOC7 "BLOM4, EXO70, Exo70p, KIAA1067, YJL085W" ENSG00000182473 "Exocyst complex component 7" Q9UPT5 17 76081016-76121576 "Human disease related genes, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022840, HPA022842" Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol "Vesicles, Plasma membrane" "HPA022840: AB_1848316, HPA022842: AB_1848317" "unprognostic (5.20e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (3.49e-2)" "unprognostic (2.37e-2)" "unprognostic (1.88e-1)" "unprognostic (1.30e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (7.39e-3)" "unprognostic (1.53e-2)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (1.05e-1)" "unprognostic (1.18e-1)" 40.4 31.4 36.0 32.7 37.0 53.2 31.2 31.4 36.7 39.3 34.1 40.1 32.5 40.1 33.1 52.3 52.3 35.4 47.2 36.8 35.5 31.9 30.2 35.9 32.7 35.4 34.3 49.6 41.1 61.2 41.0 35.3 36.5 48.1 27.9 24.7 50.6 43.1 43.0 37.0 34.7 43.5 31.9 32.4 30.3 24.9 36.4 43.5 43.0 41.4 32.3 44.3 30.1 34.8 65.6 79.4 71.9 58.5 66.6 47.0 74.5 58.9 77.6 103.9 74.7 67.5 43.0 33.7 42.0 103.0 65.6 52.7 43.9 57.1 69.0 29.3 59.1 55.8 64.0 72.3 46.4 62.9 55.7 66.1 44.3 80.5 39.2 73.5 116.9 59.8 38.1 33.7 65.6 59.8 102.1 27.8 37.8 49.5 83.4 54.0 123.3 34.6 59.7 133.6 38.9 91.4 66.5 48.6 44.6 68.8 79.7 51.0 77.5 111.3 66.3 74.1 65.8 46.0 18.2 31.2 66.4 28.0 59.0 55.1 41.1 66.1 35.5 57.4 24.4 26.7 26.9 30.4 28.9 26.9 27.7 23.9 46.2 36.4 79.7 12.3 32.0 44.9 36.0 37.0 31.4 36.7 36.8 35.5 35.4 34.3 36.5 31.9 36.4 34.8 31.0 19.2 35.0 36.6 37.7 19.8 40.1 40.8 31.3 87.6 30.2 28.8 7.5 28.6 41.4 40.5 143.9 51.5 37.5 47.6 33.2 38.3 22.4 35.1 25.8 27.1 48.9 48.6 26.2 37.1 29.0 31.6 27.0 34.4 41.1 65.0 30.7 27.0 37.7 67.3 31.1 43.8 54.9 29.6 21.3 52.2 37.3 26.9 24.9 15.0 36.8 52.1 56.7 44.2 35.0 44.6 41.4 38.4 15.7 41.5 62.8 35.3 43.7 108.8 46.0 27.8 49.5 32.1 16.6 20.3 19.9 71.1 35.8 56.6 29.8 44.8 EXOG "ENDOGL1, ENDOGL2, ENGL, ENGL-a, ENGL-b" ENSG00000157036 "Exo/endonuclease G" Q9Y2C4 3 38496127-38542161 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 59.8;Rod photoreceptor cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012531, HPA071050" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA012531: AB_2732403, HPA071050: " "unprognostic (2.88e-1)" "unprognostic (5.81e-3)" "unprognostic (3.55e-3)" "unprognostic (2.77e-1)" "unprognostic (8.32e-3)" "unprognostic (8.90e-3)" "unprognostic (4.78e-4)" "unprognostic (3.59e-2)" "unprognostic (3.99e-2)" "unprognostic (3.10e-2)" "prognostic favorable (1.92e-5)" "prognostic unfavorable (4.90e-4)" "unprognostic (6.51e-2)" "unprognostic (1.64e-2)" "unprognostic (4.79e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" 3.9 5.1 5.5 4.0 5.4 3.9 3.4 7.9 7.0 5.2 3.4 4.9 2.0 4.7 3.5 2.6 3.8 3.5 12.9 5.9 5.1 3.7 3.4 3.8 6.0 5.1 5.7 3.9 3.9 3.3 5.6 2.9 4.5 4.8 3.2 5.3 3.2 3.6 3.2 1.9 4.4 4.5 4.1 5.5 3.6 3.9 5.9 5.0 4.5 3.2 4.7 4.4 3.5 6.4 4.3 7.6 8.7 7.6 5.7 8.4 3.5 13.9 8.7 11.6 12.9 6.8 4.3 15.1 3.5 5.5 3.3 4.3 11.0 4.7 9.8 17.5 10.2 11.4 12.7 7.6 7.0 12.7 9.5 6.4 5.2 10.3 5.4 5.5 16.2 8.6 5.2 9.9 18.2 2.9 8.6 4.2 8.3 3.7 9.8 5.8 4.6 6.7 6.0 5.5 4.0 2.0 8.5 2.1 3.8 3.9 2.9 6.1 13.3 9.5 7.2 10.8 11.2 5.7 10.3 13.3 7.4 10.9 7.1 0.9 10.0 4.5 26.6 9.8 23.8 60.3 25.8 26.4 7.2 47.1 25.9 25.2 0.6 27.8 11.6 14.4 12.9 5.5 5.5 5.4 7.9 7.0 5.9 5.1 5.1 5.7 4.5 4.1 5.9 6.4 9.8 6.4 4.5 15.3 24.9 2.9 6.5 13.4 8.0 49.9 4.4 3.7 33.0 7.2 5.8 11.0 56.3 12.3 23.8 5.4 0.0 8.5 3.7 3.2 9.7 12.9 16.9 13.7 23.5 5.3 2.1 10.8 4.6 3.6 1.3 14.0 9.7 5.7 7.0 40.4 29.1 7.5 10.2 8.3 6.2 3.7 27.1 6.0 12.4 15.0 16.0 13.0 59.8 31.7 23.5 6.4 7.4 17.7 19.1 5.5 4.3 4.0 8.0 78.3 13.1 11.6 9.5 36.5 28.0 4.6 1.0 1.9 22.9 14.0 9.7 6.3 EXT1 "LGCR, LGS, ttv" ENSG00000182197 "Exostosin glycosyltransferase 1" Q16394 8 117794490-118111826 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Hereditary multiple exostoses, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 229.6;Inhibitory neurons: 421.4;Microglial cells: 144.3;Oligodendrocyte precursor cells: 162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 95.5;fHDF/TERT166: 82.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044394 Uncertain NA Yes 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044394: AB_10963838" "unprognostic (1.29e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (2.73e-2)" "unprognostic (2.02e-3)" "unprognostic (2.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.70e-1)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (6.58e-2)" "unprognostic (1.27e-2)" "unprognostic (9.84e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.85e-1)" 5.1 4.2 2.0 5.2 2.5 1.1 4.3 2.3 2.3 7.6 3.9 7.7 14.1 4.9 2.9 5.5 3.8 5.8 7.0 3.4 1.3 3.8 13.3 7.9 3.0 1.1 2.1 5.0 5.5 3.3 1.8 11.1 1.0 5.0 8.2 2.7 3.2 7.7 1.5 7.8 11.7 6.1 1.4 5.1 5.3 2.4 1.2 3.0 5.2 2.4 3.8 11.8 4.2 1.9 29.3 8.5 13.5 5.5 22.8 23.0 5.9 51.5 95.5 40.9 39.4 10.0 3.1 0.5 24.8 82.1 24.0 19.8 5.0 31.4 55.7 12.5 9.9 1.5 5.9 6.5 10.0 0.0 1.6 10.8 10.8 38.8 38.5 47.7 28.1 2.9 0.9 7.4 18.7 3.2 1.8 0.2 4.6 13.7 10.1 0.0 4.1 1.3 23.1 7.6 4.5 4.0 8.0 3.9 9.2 32.6 5.3 0.5 32.0 35.2 28.7 32.0 15.8 5.5 5.1 2.4 36.5 0.0 9.2 0.1 0.4 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.3 0.1 2.0 2.5 2.3 2.3 3.4 1.3 1.1 2.1 1.0 1.4 1.2 1.9 21.1 19.2 6.0 127.3 3.0 54.8 23.0 27.7 10.2 23.6 7.8 10.8 6.5 24.3 13.7 7.3 14.6 6.5 5.1 49.2 0.0 37.3 1.8 17.7 37.1 25.9 4.8 1.7 229.6 20.1 3.9 32.6 11.7 18.2 7.0 108.3 16.8 32.9 2.5 10.1 421.4 25.5 4.1 37.9 13.9 2.7 17.4 9.6 19.6 144.3 8.1 5.9 4.1 162.8 101.8 27.4 16.1 36.1 5.3 19.3 44.9 4.9 14.2 22.4 0.0 17.1 36.4 0.6 5.1 12.6 47.3 12.2 4.2 35.0 26.3 26.8 EXT2 SOTV ENSG00000151348 "Exostosin glycosyltransferase 2" Q93063 11 44095673-44251962 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, Hereditary multiple exostoses, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078409 Supported "Golgi apparatus" NA NA 39000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA078409: AB_2686884" "unprognostic (5.87e-2)" "unprognostic (3.05e-3)" "unprognostic (3.48e-2)" "unprognostic (3.94e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.77e-3)" "unprognostic (2.22e-2)" "unprognostic (1.97e-1)" "unprognostic (2.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.70e-2)" "prognostic unfavorable (5.36e-6)" "unprognostic (7.07e-3)" "unprognostic (2.97e-1)" "unprognostic (3.85e-1)" "unprognostic (1.36e-2)" 33.5 22.8 14.4 22.1 15.4 11.2 29.3 15.4 16.3 36.1 17.5 29.1 26.5 43.1 33.3 20.1 33.7 28.1 27.3 15.6 18.1 26.5 26.9 27.9 16.0 15.5 16.0 33.5 26.5 28.9 20.1 61.9 15.5 29.8 28.7 20.9 26.7 30.2 16.2 25.8 31.0 49.3 14.7 21.6 23.8 21.6 19.4 15.2 27.6 18.4 17.3 29.7 28.5 16.1 57.9 71.6 38.3 121.5 170.4 124.2 60.8 181.1 198.0 93.1 125.1 51.2 36.5 40.4 82.1 188.8 98.5 90.0 41.0 114.0 110.0 83.2 71.5 38.4 33.7 39.7 67.5 37.5 76.6 97.7 73.4 56.3 86.6 108.8 132.7 34.8 50.0 63.9 68.4 40.3 25.9 22.3 43.8 67.1 70.9 32.3 116.1 21.1 53.9 49.1 30.9 35.5 118.1 41.4 28.1 67.0 69.8 37.2 137.8 127.4 90.6 133.1 111.4 33.4 46.0 30.4 84.7 27.9 140.0 15.2 17.5 19.4 20.9 17.7 23.5 9.0 16.5 19.3 21.3 8.8 15.4 15.2 3.4 26.3 12.8 7.4 14.2 15.5 14.4 15.4 15.4 16.3 15.6 18.1 15.5 16.0 15.5 14.7 19.4 16.1 24.5 16.0 10.6 41.4 8.7 15.2 17.3 22.0 10.8 11.5 11.0 11.4 10.2 8.6 13.5 12.9 14.6 34.3 10.6 21.1 5.9 33.5 43.2 7.9 17.1 19.2 1.8 6.7 64.3 23.7 37.0 32.3 7.7 11.5 6.3 22.7 22.9 18.3 18.3 13.5 63.3 12.9 12.2 10.8 7.2 23.0 27.4 10.4 5.4 28.1 10.2 17.4 7.2 50.3 51.8 24.0 14.9 28.6 7.0 23.6 31.6 8.2 8.1 15.0 19.7 15.8 20.7 51.2 24.4 10.2 12.6 35.3 9.2 12.2 15.0 15.3 F2RL2 PAR3 ENSG00000164220 "Coagulation factor II thrombin receptor like 2" O00254 5 76615482-76623413 "G-protein coupled receptors, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.9;gallbladder: 6.8" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 2.3;Fibroblasts: 3.9;Hepatic stellate cells: 10.0;Rod photoreceptor cells: 5.5" "Cancer enhanced" "Detected in many" "breast cancer: 9.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "basophil: 10.4" "Lineage enriched" "Detected in many" 9 "granulocytes: 10.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 53.5;HBF TERT88: 33.8;HEL: 78.4;hTEC/SVTERT24-B: 34.8;hTERT-RPE1: 73.2;U-138 MG: 54.0;WM-115: 69.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (1.35e-3)" "unprognostic (5.71e-3)" "prognostic favorable (4.69e-4)" "unprognostic (6.71e-2)" "unprognostic (4.16e-3)" "unprognostic (3.56e-2)" "unprognostic (9.71e-2)" "unprognostic (8.49e-2)" "unprognostic (3.78e-2)" "unprognostic (1.43e-1)" "unprognostic (1.14e-1)" "unprognostic (3.20e-1)" "unprognostic (2.24e-8)" "unprognostic (7.64e-2)" "unprognostic (8.98e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" 0.3 0.4 1.2 1.8 1.5 0.3 3.8 4.4 0.2 1.3 0.1 3.5 1.6 2.3 0.1 0.8 0.3 6.8 1.8 0.2 4.4 0.3 2.0 0.6 0.1 3.9 4.7 0.1 1.0 0.3 0.4 0.2 2.9 0.3 1.7 5.0 3.7 0.1 0.0 2.3 2.3 3.8 2.3 0.3 1.3 0.0 6.9 0.8 0.2 0.5 0.3 1.0 0.3 0.5 0.0 2.0 0.2 0.2 2.3 12.1 0.0 31.3 53.5 8.3 30.0 0.0 0.1 0.0 1.8 0.2 24.8 0.1 0.0 0.2 33.8 0.0 0.1 78.4 0.7 0.2 4.7 0.1 0.1 6.7 0.2 34.8 0.1 73.2 2.9 0.2 0.0 0.1 3.0 0.0 0.0 0.0 2.8 0.0 0.3 0.0 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 54.0 16.2 2.4 0.4 2.7 0.0 0.0 6.4 0.0 69.8 10.4 0.4 0.1 0.7 0.2 0.6 0.1 0.7 0.4 0.1 0.1 0.3 0.7 0.9 1.1 0.1 1.1 0.9 0.0 1.2 1.5 4.4 0.2 0.2 4.4 3.9 4.7 2.9 2.3 6.9 0.5 0.0 0.0 0.0 0.3 0.3 0.9 0.1 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.0 1.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 2.3 1.0 0.0 0.0 0.2 0.0 0.0 3.9 1.1 0.3 0.0 0.0 10.0 0.3 0.1 0.0 0.3 0.0 0.0 1.2 1.1 0.0 0.0 0.3 0.0 0.0 0.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.5 0.0 0.0 0.1 0.6 0.0 0.9 0.0 0.0 0.1 FAM114A1 Noxp20 ENSG00000197712 "Family with sequence similarity 114 member A1" Q8IWE2 4 38867677-38945739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 2.6;granulocytes: 2.4;monocytes: 3.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 204.7;BJ hTERT+: 244.1;fHDF/TERT166: 273.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067948, HPA069104, HPA069701" Uncertain Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" No No 96000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" Nucleoplasm "HPA067948: AB_2685931, HPA069104: AB_2686087, HPA069701: AB_2686175" "unprognostic (2.13e-3)" "unprognostic (4.68e-2)" "unprognostic (1.94e-1)" "unprognostic (4.66e-2)" "unprognostic (9.40e-3)" "unprognostic (6.77e-2)" "unprognostic (2.54e-1)" "unprognostic (2.31e-2)" "unprognostic (4.88e-2)" "unprognostic (1.55e-1)" "unprognostic (3.06e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.63e-6)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-2)" "unprognostic (3.44e-3)" 28.4 48.1 7.9 23.6 11.8 2.0 20.2 7.8 9.2 48.4 23.7 34.6 22.9 29.2 17.8 35.1 19.5 36.4 23.7 9.9 11.4 11.8 54.2 21.2 8.9 13.7 12.5 41.5 25.6 22.4 18.5 35.6 11.2 35.5 33.7 3.1 61.2 27.8 16.6 15.6 24.4 61.7 9.0 8.8 34.4 12.5 12.1 4.3 17.6 22.7 19.5 35.6 26.4 13.4 43.5 30.7 18.5 21.9 197.4 204.7 6.1 167.9 244.1 69.7 105.8 8.1 33.0 0.0 23.0 273.8 118.8 11.9 0.1 53.7 80.1 0.2 4.6 3.1 30.3 40.6 70.6 0.1 5.8 122.1 17.0 101.2 23.3 157.2 101.4 0.1 3.4 0.2 102.9 11.0 0.1 2.3 3.8 18.3 15.6 0.8 90.9 3.2 23.4 8.7 0.7 9.4 33.8 0.7 33.8 42.8 20.8 3.8 156.3 75.4 34.8 95.3 39.5 0.7 0.2 0.3 123.3 3.3 63.0 0.6 3.2 0.0 0.1 3.6 0.0 0.4 0.1 0.1 2.6 0.1 0.1 0.1 2.4 0.0 1.4 0.3 0.0 0.9 7.9 11.8 7.8 9.2 9.9 11.4 13.7 12.5 11.2 9.0 12.1 13.4 28.1 16.0 13.2 5.9 2.2 12.2 47.4 43.7 15.4 0.3 29.9 21.2 17.2 14.3 56.0 7.3 0.0 2.2 0.2 46.8 9.8 45.6 1.0 17.5 88.6 35.2 15.7 3.6 1.0 61.0 47.0 94.9 35.7 39.1 1.3 30.4 31.1 68.3 16.1 0.0 1.8 78.7 83.4 7.2 15.0 6.3 110.9 8.7 21.4 17.8 6.4 12.2 0.0 14.6 31.0 47.6 41.6 116.2 8.5 92.6 39.0 11.7 47.8 1.2 19.7 49.4 44.3 1.2 5.5 23.6 10.2 3.4 3.1 94.1 32.0 82.7 FAM126A "DRCTNNB1A, HCC, HYCC1, hyccin" ENSG00000122591 "Family with sequence similarity 126 member A" Q9BYI3 7 22889371-23014130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 133.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042873 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042873: AB_2678207" "unprognostic (7.94e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (1.96e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-4)" "unprognostic (1.35e-1)" "unprognostic (9.76e-3)" "unprognostic (1.30e-2)" "unprognostic (7.23e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (6.04e-7)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.87e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (9.03e-4)" 14.9 4.7 5.0 8.5 6.9 4.2 12.2 4.4 6.5 9.7 7.9 9.7 9.4 8.7 1.4 12.2 6.7 11.4 10.5 12.1 4.5 4.7 8.5 13.7 11.5 5.0 5.9 6.6 6.2 2.3 5.0 14.8 5.4 5.9 4.4 4.9 6.8 4.8 25.0 4.9 6.9 11.5 4.5 11.8 4.6 12.0 6.3 4.2 6.6 15.3 9.2 9.4 11.2 7.8 22.4 12.4 63.6 22.3 61.3 100.9 10.6 103.0 101.8 41.6 63.9 19.8 10.6 13.3 15.9 82.6 87.2 7.7 44.3 14.7 72.6 6.6 22.4 14.7 18.1 13.0 48.0 19.3 15.7 41.1 9.2 85.0 61.3 83.4 42.5 7.5 30.4 58.6 77.5 7.9 10.8 24.2 63.0 0.1 22.9 15.7 63.5 9.5 13.1 11.2 10.4 0.1 38.1 0.4 19.2 52.5 8.2 20.4 51.0 150.0 18.3 71.8 37.4 67.2 30.6 60.9 91.1 12.5 112.6 4.7 2.9 13.7 1.4 7.8 1.3 6.4 2.6 1.3 3.9 7.4 0.9 1.5 0.3 2.1 9.8 1.6 4.0 2.5 5.0 6.9 4.4 6.5 12.1 4.5 5.0 5.9 5.4 4.5 6.3 7.8 27.8 3.2 15.1 19.6 29.1 25.5 5.1 8.3 15.9 60.3 5.4 32.4 21.9 2.8 4.2 3.7 2.1 11.8 28.8 0.5 0.0 6.8 49.0 12.5 22.4 31.4 7.7 19.8 13.6 4.8 15.5 42.9 2.6 11.3 8.2 8.6 26.0 17.7 15.2 16.8 13.6 3.0 2.0 25.1 55.2 22.4 20.2 31.5 35.6 47.8 24.0 6.8 11.3 23.6 133.2 3.6 1.4 19.5 26.4 4.7 8.3 5.7 2.4 4.6 19.7 24.0 31.7 72.2 11.1 35.0 24.0 6.0 20.6 12.2 4.7 6.5 FAM160B1 "bA106M7.3, KIAA1600" ENSG00000151553 "Family with sequence similarity 160 member B1" Q5W0V3 10 114821744-114899832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 53.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043624 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA043624: AB_10797145" "unprognostic (2.61e-1)" "unprognostic (2.47e-2)" "unprognostic (2.62e-1)" "unprognostic (8.45e-3)" "unprognostic (6.43e-2)" "unprognostic (9.87e-3)" "unprognostic (7.98e-2)" "unprognostic (3.01e-1)" "unprognostic (2.29e-1)" "unprognostic (2.45e-1)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.02e-6)" "unprognostic (3.41e-3)" "unprognostic (3.35e-1)" "unprognostic (2.10e-1)" "unprognostic (1.25e-2)" 15.0 11.7 8.7 10.0 8.4 53.3 11.9 6.1 8.4 12.1 6.1 10.7 12.7 16.0 10.0 7.3 12.3 10.5 14.2 7.8 6.5 7.9 19.0 11.6 12.6 5.6 6.5 14.3 9.8 11.9 7.4 14.9 6.1 10.5 8.1 11.5 8.5 11.3 20.3 8.6 13.2 16.9 5.3 11.4 10.1 18.8 6.9 11.2 11.7 12.3 9.6 11.9 10.0 5.2 16.7 8.9 9.6 14.3 22.9 26.0 11.2 29.7 28.8 16.8 13.4 3.1 6.3 9.9 9.1 27.2 4.3 11.0 4.7 11.9 19.8 36.2 10.2 3.9 16.5 7.2 16.7 10.6 12.8 20.4 11.3 12.5 20.2 36.0 22.9 20.0 5.6 24.4 31.7 7.7 19.0 10.5 6.3 4.8 6.6 16.3 16.3 6.6 11.3 9.9 2.1 8.6 13.2 13.6 15.5 11.3 5.4 6.0 23.1 10.4 6.6 30.7 10.4 10.0 3.0 11.2 13.4 26.0 10.0 19.9 3.2 4.7 5.4 2.4 4.0 3.7 7.4 9.2 3.6 3.6 4.0 5.5 15.2 4.9 2.8 3.7 10.5 2.7 8.7 8.4 6.1 8.4 7.8 6.5 5.6 6.5 6.1 5.3 6.9 5.2 25.9 16.0 8.1 20.5 10.9 7.0 7.9 8.0 14.8 13.9 9.4 6.7 19.5 4.3 8.4 3.7 12.5 12.7 14.1 9.0 1.9 10.2 26.7 12.0 26.2 19.8 7.8 9.9 26.5 9.6 10.2 19.2 23.0 16.8 2.5 29.6 23.9 31.3 6.3 10.1 27.4 9.2 4.1 15.6 6.8 36.0 28.6 11.3 3.6 25.3 11.4 8.3 25.7 28.1 13.8 15.1 3.7 22.2 20.1 19.5 20.8 6.6 8.7 16.9 6.6 13.2 14.4 14.9 6.4 8.9 4.8 12.6 17.5 15.0 5.8 14.8 FAM160B2 "FLJ21801, RAI16" ENSG00000158863 "Family with sequence similarity 160 member B2" Q86V87 8 22089150-22104911 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025040 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm Cytosol "HPA025040: AB_1856049" "unprognostic (3.45e-1)" "unprognostic (2.08e-3)" "unprognostic (1.60e-1)" "unprognostic (8.85e-3)" "unprognostic (2.28e-2)" "prognostic favorable (4.56e-4)" "unprognostic (2.35e-2)" "unprognostic (4.82e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-2)" "unprognostic (8.38e-3)" "unprognostic (7.67e-3)" "unprognostic (3.38e-2)" "unprognostic (6.30e-2)" "unprognostic (1.08e-2)" "unprognostic (1.25e-1)" "unprognostic (2.75e-3)" 13.9 11.5 4.5 3.9 4.1 3.6 15.8 3.5 5.5 12.5 3.5 16.2 5.8 12.3 4.9 13.6 12.7 5.6 21.7 3.6 3.5 14.6 10.5 10.6 6.3 4.8 4.2 10.0 22.3 8.2 13.2 5.2 4.1 14.6 2.5 3.0 16.7 10.6 17.7 14.0 13.5 6.9 3.7 11.4 17.4 6.1 4.8 4.2 15.4 7.2 2.2 16.2 12.0 4.6 4.4 8.7 4.3 6.8 9.2 8.1 7.8 8.0 13.6 8.6 5.8 3.9 4.7 4.9 7.7 19.7 7.8 6.3 3.3 9.3 1.9 4.1 4.2 7.3 2.8 2.2 12.4 1.9 5.7 13.6 6.9 6.6 4.4 8.9 9.1 8.8 4.6 3.3 8.3 8.0 5.0 2.9 2.1 8.0 3.8 5.1 3.7 2.5 7.4 8.9 1.8 5.8 4.6 6.6 5.2 4.5 4.3 3.2 10.3 8.4 7.2 8.0 4.6 3.5 0.9 0.9 9.0 3.1 9.7 0.0 0.4 0.1 0.8 0.2 0.5 0.7 0.5 0.6 0.2 0.5 0.4 0.7 0.0 0.4 0.4 0.2 0.0 0.7 4.5 4.1 3.5 5.5 3.6 3.5 4.8 4.2 4.1 3.7 4.8 4.6 16.4 12.8 17.2 17.0 11.6 5.9 10.1 9.9 12.5 22.0 16.4 13.5 26.1 12.8 8.8 12.9 27.1 8.5 10.1 15.5 0.0 9.7 3.7 8.9 14.5 16.8 13.2 1.3 12.3 15.0 15.5 12.5 23.0 11.8 7.0 19.1 16.8 13.6 7.4 23.5 12.0 10.8 0.0 9.4 4.7 2.5 10.8 8.2 1.8 8.4 4.4 8.7 9.2 12.1 11.0 17.1 17.1 5.7 6.3 15.1 14.7 5.0 10.8 23.8 0.0 11.0 14.7 1.5 7.0 16.1 7.5 14.9 11.2 9.6 9.9 12.4 FAM162B "bA86F4.2, C6orf189" ENSG00000183807 "Family with sequence similarity 162 member B" Q5T6X4 6 116752197-116765719 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 65.2" "Group enriched" "Detected in some" 4 "Adipocytes: 34.6;Sertoli cells: 65.7;Smooth muscle cells: 105.1" "Cancer enriched" "Detected in many" 18 "testis cancer: 32.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 8.7;BJ hTERT+: 23.5;BJ hTERT+ SV40 Large T+ RasG12V: 22.1;HHSteC: 6.3;HSkMC: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036112, HPA060342" Enhanced NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA036112: AB_10696649, HPA060342: AB_2684258" "unprognostic (1.81e-1)" "unprognostic (5.65e-3)" "unprognostic (1.54e-1)" "unprognostic (3.38e-1)" "unprognostic (5.45e-2)" "unprognostic (1.86e-5)" "unprognostic (8.29e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-2)" "unprognostic (2.44e-2)" "unprognostic (7.32e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.22e-2)" "unprognostic (1.72e-1)" "unprognostic (2.73e-3)" "unprognostic (4.34e-2)" 14.7 14.9 3.3 0.8 4.4 0.0 10.9 1.9 7.0 13.2 2.5 3.3 0.9 5.8 7.5 4.4 10.1 5.2 9.1 4.6 2.7 4.5 0.9 17.9 1.5 3.0 2.5 5.7 1.7 3.7 6.6 65.2 2.7 6.2 2.1 0.2 8.2 13.4 5.4 3.0 2.3 3.7 2.7 0.1 3.5 2.5 2.8 1.8 9.7 10.6 1.2 7.9 9.9 4.7 0.0 0.0 0.0 0.0 2.3 0.1 0.0 8.7 23.5 3.7 22.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.4 1.9 7.0 4.6 2.7 3.0 2.5 2.7 2.7 2.8 4.7 34.6 0.0 0.0 1.3 0.0 1.3 0.1 0.0 1.2 0.0 0.9 0.8 0.9 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 16.9 0.7 15.7 13.7 0.0 0.0 14.8 0.0 0.2 14.1 0.0 0.4 0.0 0.1 3.6 0.0 0.5 0.0 6.9 0.0 0.0 0.0 2.1 2.2 2.1 0.7 1.8 3.7 0.0 0.0 0.0 6.6 0.5 0.2 0.0 5.3 0.0 0.2 0.0 0.1 0.0 0.1 65.7 2.2 105.1 10.3 5.9 0.6 0.9 0.5 2.3 0.1 0.0 0.0 FAM214B "bA182N22.6, FLJ11560, KIAA1539" ENSG00000005238 "Family with sequence similarity 214 member B" Q7L5A3 9 35104112-35116341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 54.1;Late spermatids: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.3" "Group enriched" "Detected in many" 5 "dendritic cells: 4.8;granulocytes: 16.3;monocytes: 10.2" "Cell line enhanced" "Detected in many" "TIME: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048831, HPA055751" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Nucleoli fibrillar center" "HPA048831: AB_2680535, HPA055751: AB_2682906" "unprognostic (2.91e-3)" "unprognostic (1.56e-1)" "unprognostic (2.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.10e-1)" "unprognostic (2.26e-1)" "unprognostic (7.22e-3)" "unprognostic (1.04e-1)" "unprognostic (1.06e-1)" "unprognostic (7.72e-3)" "unprognostic (2.38e-2)" "unprognostic (1.70e-2)" "unprognostic (1.02e-2)" "unprognostic (2.92e-1)" "unprognostic (1.31e-1)" "unprognostic (1.10e-2)" "unprognostic (8.15e-2)" 13.9 14.9 26.7 12.2 27.4 38.8 10.6 27.2 29.4 11.8 20.7 15.2 10.2 10.6 7.0 29.7 8.9 11.7 19.7 26.0 26.9 14.9 11.3 21.7 6.8 30.8 29.0 8.0 6.8 11.2 15.8 9.9 29.6 13.0 10.5 4.3 11.6 9.7 14.2 15.0 11.2 11.0 27.4 27.6 11.7 8.5 30.8 5.9 11.7 11.5 7.0 12.3 14.4 28.3 6.4 5.2 14.2 10.3 11.0 16.9 3.0 31.2 27.9 17.0 10.9 3.6 4.4 1.6 9.0 50.5 44.0 2.8 2.4 10.0 11.0 8.3 0.6 7.9 12.6 3.4 11.2 2.2 33.4 12.1 17.4 19.9 12.5 39.3 33.1 7.9 4.4 6.3 36.0 1.8 3.1 9.8 2.7 4.8 7.8 3.5 2.4 1.9 22.3 1.4 1.0 9.3 4.9 3.5 16.6 14.8 4.6 5.3 56.0 23.8 11.5 11.5 11.5 4.0 4.1 0.8 37.5 4.0 26.7 5.0 5.9 5.7 2.1 7.7 0.7 0.5 1.3 1.5 4.8 0.2 0.5 0.9 16.3 2.1 10.2 1.2 0.8 3.4 26.7 27.4 27.2 29.4 26.0 26.9 30.8 29.0 29.6 27.4 30.8 28.3 10.8 0.0 3.9 17.9 3.1 8.4 4.4 11.7 11.4 3.3 8.6 5.2 8.6 2.8 6.2 16.5 14.6 2.8 7.9 43.0 3.9 11.3 12.7 5.5 7.0 11.3 5.4 54.1 5.8 12.5 9.6 6.9 9.2 7.8 8.8 3.8 18.2 6.7 14.9 0.0 5.4 12.3 12.2 28.2 21.3 77.0 3.4 32.5 16.0 4.7 26.2 8.4 16.5 2.5 14.4 40.0 19.8 7.9 3.5 6.9 14.1 11.7 4.4 3.6 6.6 7.3 9.2 3.0 6.5 23.6 14.5 4.2 7.5 5.3 14.0 9.3 FAM98A DKFZP564F0522 ENSG00000119812 "Family with sequence similarity 98 member A" Q8NCA5 2 33583660-33599382 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036250, HPA036251" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "HPA036250: AB_2675020, HPA036251: AB_10673124" "unprognostic (7.25e-2)" "unprognostic (9.92e-2)" "unprognostic (1.59e-2)" "unprognostic (1.40e-1)" "unprognostic (1.51e-1)" "unprognostic (2.42e-2)" "prognostic unfavorable (4.86e-7)" "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (3.51e-1)" "unprognostic (2.02e-2)" "unprognostic (2.38e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (8.18e-5)" "unprognostic (6.01e-2)" 29.2 21.5 21.4 20.5 26.5 7.2 16.3 28.6 30.4 21.7 27.9 20.7 13.6 19.1 19.3 19.9 12.2 15.7 40.6 30.8 25.7 27.4 25.5 11.5 18.4 25.1 24.5 16.5 14.6 51.2 20.5 20.6 29.5 23.0 17.1 17.2 28.0 16.7 61.3 14.9 12.1 36.4 27.7 14.3 19.8 49.4 26.4 17.4 19.2 62.4 22.6 27.5 12.9 39.7 93.4 47.2 25.5 43.9 99.4 108.3 41.9 224.1 81.6 62.3 80.2 49.8 18.8 144.5 41.3 101.8 55.3 41.3 84.8 60.8 84.2 67.7 56.3 119.7 46.9 69.3 47.2 95.5 44.7 56.1 42.2 83.9 52.1 63.5 83.3 15.5 84.4 43.8 108.7 46.1 53.3 28.5 64.4 83.2 59.9 41.1 82.5 51.9 65.0 72.2 45.6 26.1 60.0 89.5 27.0 40.7 36.2 15.6 135.7 39.5 66.1 82.9 89.2 80.2 106.6 142.4 91.2 68.2 56.8 1.3 4.1 2.3 6.4 7.2 6.9 10.7 5.4 5.8 6.1 5.5 6.9 5.7 0.1 4.0 4.6 3.5 9.0 4.1 21.4 26.5 28.6 30.4 30.8 25.7 25.1 24.5 29.5 27.7 26.4 39.7 19.0 22.4 11.5 6.8 17.4 20.4 19.0 12.2 18.8 16.8 15.0 14.0 74.6 11.5 19.8 7.3 2.1 25.5 9.8 6.9 25.4 20.3 14.9 16.7 29.9 21.1 5.4 12.8 22.8 29.2 33.2 31.9 17.9 18.9 2.5 44.4 17.2 23.4 16.4 47.1 15.7 15.1 8.2 7.7 11.8 13.8 22.4 8.7 8.8 6.5 5.9 17.4 16.5 9.0 36.1 26.0 8.7 21.8 40.3 22.6 9.3 46.2 16.5 15.7 0.0 21.7 27.1 41.5 40.1 26.1 20.5 40.0 13.7 54.9 12.1 23.4 FAT1 "CDHF7, CDHR8, FAT" ENSG00000083857 "FAT atypical cadherin 1" Q14517 4 186587794-186726722 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 119.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 285.7;LHCN-M2: 206.7" "Low region specificity" "Detected in all" "HPA001869, HPA023882" Enhanced "Intracellular and membrane" NA NA 4600000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA001869: AB_1078818, HPA023882: AB_1848429" "unprognostic (1.98e-1)" "unprognostic (4.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.86e-1)" "unprognostic (1.53e-2)" "unprognostic (5.82e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.15e-3)" "unprognostic (6.80e-2)" "unprognostic (3.57e-2)" "unprognostic (8.03e-3)" "unprognostic (9.41e-2)" "unprognostic (6.25e-3)" "unprognostic (4.27e-2)" 20.1 1.3 14.5 7.2 20.2 0.8 21.9 31.1 12.4 20.0 119.2 35.0 25.9 23.4 16.0 13.3 9.8 23.5 24.8 14.3 27.0 22.1 10.0 12.9 2.4 40.1 42.3 10.4 12.6 11.4 9.7 17.0 24.4 21.4 31.4 3.4 18.7 24.2 3.5 17.5 24.2 25.7 22.1 2.2 16.8 9.7 22.2 6.0 14.6 3.9 4.4 32.0 11.0 22.0 22.2 83.5 80.9 0.3 79.1 94.5 19.9 110.9 181.9 52.8 33.5 50.0 49.0 0.0 26.0 285.7 34.1 40.4 32.0 136.7 71.6 0.2 13.2 0.0 30.5 50.8 39.4 37.3 29.2 34.5 48.4 98.7 63.5 72.4 1.1 44.8 0.6 0.0 206.7 27.1 66.2 0.1 18.1 42.2 13.9 0.3 22.3 1.8 79.2 79.0 8.6 32.3 19.2 32.2 12.7 54.9 0.3 13.3 23.8 149.8 57.9 2.0 69.8 0.4 0.2 0.5 34.1 0.1 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 20.2 31.1 12.4 14.3 27.0 40.1 42.3 24.4 22.1 22.2 22.0 6.1 16.0 6.7 55.2 0.3 85.0 27.2 115.4 27.3 5.2 26.5 27.6 27.6 38.6 40.7 53.3 0.0 1.6 0.2 71.2 5.9 25.2 0.7 25.7 17.2 5.0 14.5 0.0 5.8 26.5 3.6 28.8 54.0 29.6 16.5 75.0 1.1 26.1 0.4 0.0 30.3 56.4 18.3 0.8 7.3 0.9 14.6 1.7 12.4 5.6 0.0 4.5 0.0 14.1 12.4 30.3 30.0 37.2 0.2 55.8 78.2 26.7 37.0 0.4 39.5 23.1 65.1 1.5 10.4 10.2 46.9 1.6 1.9 11.7 45.1 38.9 FCHSD1 FLJ00007 ENSG00000197948 "FCH and double SH3 domains 1" Q86WN1 5 141639302-141651418 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 50.8" "Cell type enhanced" "Detected in many" "Horizontal cells: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043795 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm Cytosol "HPA043795: AB_10963435" "prognostic favorable (8.62e-4)" "unprognostic (4.08e-2)" "unprognostic (6.17e-2)" "unprognostic (5.28e-2)" "unprognostic (3.50e-3)" "unprognostic (8.56e-3)" "unprognostic (5.34e-2)" "unprognostic (9.61e-3)" "unprognostic (2.17e-2)" "unprognostic (2.66e-2)" "unprognostic (1.88e-3)" "unprognostic (1.50e-2)" "prognostic unfavorable (6.19e-6)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.77e-4)" "unprognostic (4.12e-3)" "prognostic favorable (1.21e-4)" 8.3 6.7 4.0 19.6 5.2 19.7 8.8 5.7 5.3 16.0 2.8 9.2 11.1 12.5 3.4 9.0 11.0 11.3 5.6 3.1 7.5 7.5 2.8 10.7 23.0 7.2 6.0 17.4 7.7 50.8 13.1 6.7 7.6 10.5 5.2 3.6 11.2 6.3 1.9 21.3 17.2 6.1 3.7 22.2 11.7 3.9 7.1 11.0 11.1 1.9 16.9 11.7 14.3 7.3 13.5 8.3 11.0 23.1 9.2 11.5 19.3 28.5 14.5 25.1 39.3 15.7 28.1 5.6 14.0 22.1 4.0 7.5 3.5 15.8 11.2 23.9 6.0 11.7 12.9 5.8 7.0 3.7 38.1 14.2 12.3 19.8 6.4 21.1 14.6 0.4 7.4 10.3 2.9 11.8 3.0 7.1 3.2 4.7 7.6 0.1 0.1 5.5 8.6 19.8 1.2 12.2 0.5 10.6 16.5 8.3 12.9 11.0 29.8 0.4 6.9 10.3 12.1 12.2 4.4 2.9 21.8 13.1 12.2 5.8 1.2 4.0 4.3 1.3 3.3 3.3 2.4 4.6 1.2 1.7 2.2 3.1 6.5 1.6 2.1 1.2 3.5 2.4 4.0 5.2 5.7 5.3 3.1 7.5 7.2 6.0 7.6 3.7 7.1 7.3 4.0 0.0 2.2 5.5 11.6 2.7 3.7 4.7 9.6 4.9 3.5 4.1 0.6 2.8 3.6 3.7 12.5 1.1 11.4 6.3 0.0 4.7 7.1 1.8 2.9 3.8 4.2 1.3 1.7 6.5 4.3 5.3 9.2 3.4 8.9 4.9 3.9 0.6 5.6 53.8 3.9 4.6 8.2 1.9 1.9 6.6 4.1 5.6 3.6 4.7 3.5 1.9 15.5 0.5 8.6 7.4 3.4 3.8 8.2 2.4 4.3 0.7 3.6 1.7 6.6 2.4 3.8 2.3 4.0 4.4 2.8 1.4 14.4 3.5 2.6 2.3 FCRLB "FCRL2, FCRLM2, FCRLY, FLJ31052, FREB-2" ENSG00000162746 "Fc receptor like B" Q6BAA4 1 161721563-161728143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 7.5;NK-cells: 11.3;Proximal tubular cells: 14.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 7.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.8;Daudi: 6.0;fHDF/TERT166: 8.8;HMC-1: 7.4;PC-3: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" CAB026139 Uncertain Supported Cytosol "Intracellular and membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB026139: " "unprognostic (1.87e-1)" "unprognostic (1.20e-4)" "unprognostic (5.77e-3)" "unprognostic (7.49e-3)" "unprognostic (1.73e-3)" "unprognostic (2.95e-1)" "unprognostic (2.98e-2)" "unprognostic (1.18e-3)" "unprognostic (1.89e-1)" "unprognostic (3.59e-2)" "unprognostic (1.39e-1)" "unprognostic (1.60e-1)" "unprognostic (1.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.27e-1)" "unprognostic (9.92e-3)" "unprognostic (3.14e-2)" 0.2 0.1 0.5 0.7 0.4 0.0 0.1 0.5 0.7 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.4 0.7 0.3 0.1 0.9 0.5 0.5 0.1 0.2 0.1 0.0 0.1 0.6 0.1 0.1 0.1 0.3 0.9 0.0 0.2 0.1 0.0 0.4 0.3 0.1 0.1 0.4 0.0 0.1 0.0 1.8 0.2 0.1 0.6 0.6 0.1 0.0 0.3 0.4 0.6 0.0 3.7 4.8 1.2 1.2 0.1 0.1 6.0 0.2 8.8 0.2 0.0 0.2 0.3 3.1 0.1 0.3 0.2 0.1 0.1 0.2 0.0 7.4 1.1 0.0 2.1 0.1 0.3 1.1 0.0 0.3 0.3 0.1 0.3 0.0 2.1 0.1 0.0 4.4 0.0 0.4 0.2 0.1 0.2 0.0 0.0 0.0 0.1 1.9 0.2 0.0 0.0 0.6 1.3 0.6 1.3 0.7 0.0 0.0 2.3 2.5 0.4 0.6 6.4 0.1 1.8 1.8 0.0 0.6 3.4 1.1 1.0 0.4 4.7 0.5 0.8 1.0 3.7 0.2 0.0 0.0 0.5 0.5 0.4 0.5 0.7 0.5 0.4 0.5 0.5 0.6 0.4 0.4 0.6 2.8 0.0 0.0 0.3 2.9 1.1 1.1 1.0 0.6 0.2 1.5 1.5 1.5 0.0 1.2 3.7 0.0 2.1 3.9 0.1 5.9 1.3 0.1 0.3 1.3 2.3 1.2 5.3 0.9 1.1 5.6 1.1 0.0 0.4 0.0 1.2 7.5 1.2 1.4 0.0 1.2 0.0 0.0 1.9 1.2 0.2 0.0 3.4 1.8 0.0 0.7 3.4 11.3 0.0 0.3 1.0 0.1 0.4 3.0 0.6 0.0 14.7 0.7 0.7 0.0 0.2 1.6 2.7 1.4 1.3 0.4 0.8 2.4 2.2 0.0 1.1 FEZ2 ENSG00000171055 "Fasciculation and elongation protein zeta 2" Q9UHY8 2 36531805-36646087 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035978 Uncertain Approved "Nucleoli,Nucleoli rim,Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" "Golgi apparatus, Cytosol" "HPA035978: AB_10672235" "unprognostic (1.42e-1)" "unprognostic (5.02e-3)" "unprognostic (2.89e-1)" "unprognostic (1.15e-2)" "unprognostic (2.91e-2)" "unprognostic (1.94e-3)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.09e-1)" "unprognostic (7.05e-2)" "unprognostic (2.42e-1)" "unprognostic (1.09e-1)" "unprognostic (1.28e-1)" "unprognostic (6.65e-2)" "unprognostic (7.82e-3)" "unprognostic (7.07e-2)" "unprognostic (3.47e-2)" "unprognostic (1.82e-1)" 53.0 39.1 48.2 21.0 51.6 16.5 35.9 48.2 68.6 26.9 42.8 34.5 22.1 33.1 18.9 31.7 23.8 23.6 46.7 49.2 48.4 33.6 29.4 27.1 24.3 49.5 46.3 27.6 10.8 20.3 14.2 46.8 48.2 23.5 27.9 26.5 17.1 32.5 108.1 17.0 28.5 41.1 50.1 30.3 21.9 20.8 49.6 18.2 23.9 78.5 19.5 29.1 24.3 56.3 64.9 37.1 49.4 22.3 91.3 122.1 39.5 157.1 76.5 90.7 56.0 24.6 21.5 39.1 94.7 199.2 41.0 25.1 42.4 54.3 98.5 9.3 24.7 31.7 12.2 43.5 44.4 32.9 8.5 119.9 44.2 57.8 69.6 61.2 131.0 9.5 35.4 12.0 170.2 22.7 19.6 27.5 27.1 33.9 57.8 16.9 44.3 14.0 72.9 57.6 1.9 45.7 38.7 31.9 37.8 51.7 11.3 39.1 161.2 59.7 32.9 33.4 92.9 9.8 11.5 26.6 58.9 22.4 84.8 2.5 3.5 5.1 1.7 3.4 1.0 1.6 1.3 1.0 3.5 1.0 1.5 0.7 4.2 3.2 2.3 15.6 1.4 0.8 48.2 51.6 48.2 68.6 49.2 48.4 49.5 46.3 48.2 50.1 49.6 56.3 109.4 54.5 37.5 25.8 23.7 31.4 94.7 45.5 41.5 52.5 31.7 33.1 43.1 17.2 70.2 58.8 45.9 96.4 61.1 57.6 56.7 80.3 5.6 38.4 44.7 100.9 24.0 15.3 45.4 30.6 87.6 50.7 27.0 64.3 24.1 66.0 97.5 37.2 93.7 21.9 22.9 28.8 38.7 88.1 65.4 10.7 54.3 64.6 56.9 45.0 56.0 97.1 35.0 23.1 50.5 74.4 41.4 66.2 17.9 99.1 65.6 45.1 35.9 36.3 59.2 64.0 51.2 12.1 34.9 24.0 32.1 180.1 24.2 47.2 37.7 140.6 FGF1 "AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1" ENSG00000113578 "Fibroblast growth factor 1" P05230 5 142592178-142698070 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 295.2;choroid plexus: 125.8" "Cell type enhanced" "Detected in many" "Astrocytes: 75.1;Cardiomyocytes: 62.4;Muller glia cells: 69.4;Oligodendrocytes: 119.8" "Cancer enriched" "Detected in many" 12 "glioma: 33.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.6;BJ hTERT+: 33.0;BJ hTERT+ SV40 Large T+: 35.9;BJ hTERT+ SV40 Large T+ RasG12V: 45.0;HBF TERT88: 64.3;hTEC/SVTERT24-B: 45.4;LHCN-M2: 30.6;U-2 OS: 33.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003265, CAB017519" Enhanced Supported Nucleoplasm "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB017519: AB_629473, HPA003265: AB_1848522" "unprognostic (1.25e-2)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (2.55e-2)" "unprognostic (3.52e-1)" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.63e-1)" "unprognostic (1.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.54e-1)" "prognostic favorable (2.59e-5)" "unprognostic (3.72e-4)" "unprognostic (2.49e-1)" "prognostic favorable (3.45e-5)" "unprognostic (3.01e-4)" 17.9 3.3 206.3 1.6 259.3 1.1 12.5 213.9 295.2 1.3 125.8 2.4 1.0 3.1 7.9 2.0 1.7 2.5 50.2 183.5 245.5 66.5 1.7 2.8 1.2 236.2 237.7 0.9 0.8 4.3 6.5 2.1 259.9 1.8 1.3 18.8 7.3 2.3 2.2 1.7 1.2 2.5 225.4 6.9 0.8 2.0 244.3 1.5 5.6 7.8 2.0 1.2 1.0 272.8 5.6 0.3 0.3 1.5 1.1 3.3 1.8 44.6 33.0 35.9 45.0 0.2 0.2 1.3 3.1 15.4 2.1 0.7 0.0 3.5 64.3 0.2 0.0 0.0 0.8 0.4 0.6 0.0 0.4 1.6 1.1 45.4 2.7 9.7 0.0 0.2 0.0 1.6 30.6 0.7 0.1 0.9 1.4 0.1 1.4 0.2 1.5 0.6 1.5 0.2 1.1 2.3 0.1 0.9 0.6 8.0 0.0 0.2 1.1 5.8 33.0 0.8 21.3 0.8 0.4 0.3 8.2 0.3 1.6 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.3 0.3 0.0 0.1 0.2 0.1 0.0 206.3 259.3 213.9 295.2 183.5 245.5 236.2 237.7 259.9 225.4 244.3 272.8 1.4 0.0 0.0 75.1 0.1 0.4 5.0 5.7 7.4 3.5 1.2 25.4 62.4 0.0 2.1 20.2 16.7 1.1 0.1 0.0 0.0 1.1 0.4 0.0 0.7 4.8 0.0 0.0 13.0 0.0 0.5 4.7 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 14.6 0.0 12.2 0.0 0.0 1.4 0.0 0.2 3.6 29.0 0.0 69.4 0.0 15.1 119.8 0.6 0.0 0.4 0.0 5.3 0.0 0.3 0.1 11.6 6.6 0.5 23.4 0.1 0.1 0.6 0.0 0.8 0.4 0.0 0.0 0.7 FGF2 FGFB ENSG00000138685 "Fibroblast growth factor 2" P09038 4 122826708-122898236 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 33.7;Astrocytes: 111.0;Endometrial stromal cells: 40.6;Fibroblasts: 77.1;Oligodendrocyte precursor cells: 42.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 243.8;BJ hTERT+: 148.4;fHDF/TERT166: 278.2;hTERT-HME1: 147.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000125, HPA065502" Enhanced Supported "Nucleoplasm,Nuclear bodies" "Secreted in other tissues" NA NA 92500 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear bodies" "CAB000125: , HPA065502: " "unprognostic (1.53e-2)" "unprognostic (3.12e-1)" "unprognostic (1.08e-1)" "unprognostic (7.42e-2)" "unprognostic (2.10e-1)" "unprognostic (3.33e-1)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (2.82e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (9.85e-4)" "unprognostic (3.37e-1)" "unprognostic (4.61e-3)" "unprognostic (2.36e-1)" "unprognostic (1.81e-1)" "unprognostic (4.45e-2)" "unprognostic (3.45e-3)" 24.3 2.6 14.8 5.3 16.1 0.1 9.5 12.2 14.7 8.7 14.2 14.1 1.7 14.2 4.5 4.7 8.0 7.1 5.0 12.2 18.8 4.0 2.0 8.3 1.8 18.6 20.5 12.6 1.5 4.7 3.2 6.4 15.6 7.6 4.0 3.4 3.5 8.7 1.4 1.9 3.7 12.6 16.8 1.1 6.2 1.9 18.3 1.6 2.4 4.8 1.8 14.8 6.1 13.3 4.7 14.1 7.8 30.5 18.8 31.1 0.0 243.8 148.4 104.3 60.2 0.2 0.4 0.0 20.5 278.2 81.8 0.7 8.1 0.5 104.3 12.3 3.3 0.0 28.7 0.2 55.3 1.4 0.1 16.8 1.7 103.6 147.6 52.0 11.8 0.0 6.9 8.4 27.4 0.1 0.1 0.2 21.6 0.1 5.4 0.0 3.9 0.1 33.0 0.0 4.4 4.0 48.4 0.1 2.0 44.7 0.1 0.5 10.6 85.7 12.2 32.0 20.0 8.6 10.3 0.0 24.7 0.1 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 16.1 12.2 14.7 12.2 18.8 18.6 20.5 15.6 16.8 18.3 13.3 33.7 6.4 0.0 111.0 0.3 1.7 1.6 0.8 2.8 4.6 4.5 8.9 4.7 0.0 1.3 7.3 0.0 2.7 0.4 0.0 3.9 8.2 10.9 1.5 40.6 11.5 1.8 0.4 1.8 1.0 0.1 77.1 0.0 1.6 0.0 5.7 17.2 1.3 0.5 0.0 6.6 0.0 0.0 0.0 2.4 3.8 9.9 1.7 5.4 15.9 0.6 9.3 0.0 42.3 5.8 11.0 0.0 8.2 1.6 16.0 0.0 0.6 0.0 2.0 0.0 15.2 14.2 4.7 1.1 0.3 1.3 4.8 0.5 0.1 0.0 2.0 FGF5 ENSG00000138675 "Fibroblast growth factor 5" P12034 4 80266599-80336680 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.7;gallbladder: 3.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Excitatory neurons: 9.4;Microglial cells: 1.9;Proximal tubular cells: 4.1" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 11.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 64.1;BJ hTERT+: 120.0;fHDF/TERT166: 88.0;HBF TERT88: 88.0;LHCN-M2: 81.1;U-138 MG: 109.5;U-251 MG: 55.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB010313, HPA042442" Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010313: AB_2102677, HPA042442: AB_2678001" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (8.49e-4)" "unprognostic (1.10e-1)" "unprognostic (2.91e-1)" "unprognostic (2.80e-3)" "unprognostic (6.87e-4)" "unprognostic (2.53e-1)" "unprognostic (1.69e-1)" "unprognostic (3.57e-3)" "unprognostic (1.17e-2)" "unprognostic (3.33e-16)" "unprognostic (3.02e-3)" "unprognostic (3.14e-1)" "unprognostic (2.83e-2)" 0.0 0.0 0.2 0.6 0.0 0.1 0.0 11.7 1.2 0.0 0.0 1.4 0.1 0.1 0.0 0.1 0.0 3.4 0.1 0.6 0.0 0.8 0.0 0.0 0.0 2.7 0.2 0.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.1 1.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.1 6.1 21.8 0.0 64.1 120.0 16.5 12.2 0.0 0.1 0.0 0.0 88.0 1.2 0.1 0.1 22.5 88.0 0.0 1.1 0.2 0.1 0.0 1.7 0.6 0.0 6.3 0.0 48.6 23.0 27.9 5.7 0.0 0.0 0.2 81.1 0.0 0.1 0.3 0.1 0.0 2.1 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.8 0.0 0.0 0.2 20.9 109.5 4.6 5.4 55.0 0.0 0.0 0.1 6.3 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 11.7 1.2 0.6 0.0 2.7 0.2 3.0 0.0 0.5 0.5 0.0 0.0 1.1 0.3 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.6 0.0 0.1 0.0 0.0 0.0 9.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 4.1 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 FHL1 "bA535K18.1, FHL1B, FLH1A, KYO-T, MGC111107, SLIM1, XMPMA" ENSG00000022267 "Four and a half LIM domains 1" Q13642 X 136146702-136211359 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 11467.1;tongue: 9770.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1145.1;Early spermatids: 373.8;Late spermatids: 1206.9" "Cancer enhanced" "Detected in all" "renal cancer: 88.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 36.1" "Group enriched" "Detected in many" 4 "dendritic cells: 19.4;NK-cells: 36.1;T-cells: 18.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 303.7;fHDF/TERT166: 258.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001040, HPA001391, CAB020817" Enhanced Supported "Plasma membrane,Cytosol" NA NA 12000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "CAB020817: , HPA001040: AB_1848541, HPA001391: AB_1848542" "unprognostic (2.16e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.61e-3)" "unprognostic (1.76e-2)" "unprognostic (2.51e-2)" "unprognostic (9.34e-2)" "unprognostic (7.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (1.72e-1)" "unprognostic (6.17e-3)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.05e-3)" "prognostic unfavorable (2.11e-4)" 938.4 65.8 120.8 75.5 117.2 11.7 441.8 95.9 126.3 315.5 85.8 672.0 83.2 464.6 107.7 538.1 281.6 127.6 1462.3 130.8 144.9 45.2 43.1 285.6 41.7 103.9 125.4 102.8 39.4 196.5 92.9 106.6 115.9 408.8 161.4 76.2 161.3 541.1 11467.1 101.3 235.5 486.5 114.8 43.0 368.4 60.2 130.1 25.1 310.1 9770.8 32.1 469.6 253.1 102.9 0.4 44.3 60.7 57.8 127.2 52.3 1.5 183.7 303.7 34.8 81.3 0.3 12.7 0.7 55.8 258.8 95.0 0.5 119.2 148.0 28.2 0.4 136.7 0.7 34.4 0.0 121.6 0.3 26.8 96.6 24.4 41.2 128.7 14.1 36.6 34.5 0.1 26.0 81.9 2.5 26.1 1.6 19.1 0.2 52.2 69.8 2.6 38.2 1.1 0.1 43.5 63.8 6.6 0.2 12.4 24.1 0.3 2.4 102.5 150.2 71.0 5.9 44.7 6.8 16.0 1.1 11.9 1.4 18.2 0.1 0.7 0.0 5.2 0.1 13.8 5.8 18.2 7.2 3.1 3.6 12.0 4.0 1.2 36.1 0.0 19.4 2.2 11.1 120.8 117.2 95.9 126.3 130.8 144.9 103.9 125.4 115.9 114.8 130.1 102.9 203.0 48.1 11.7 32.0 8.1 56.5 26.9 15.1 14.2 36.2 1.4 8.3 1145.1 0.0 4.9 11.0 8.4 0.6 8.6 0.5 1.9 3.0 373.8 4.3 32.3 61.1 13.8 17.9 70.2 0.2 1.1 236.0 2.0 2.0 15.8 41.0 113.6 6.1 4.3 99.3 55.6 0.8 0.0 5.1 47.0 1206.9 123.9 35.6 32.0 16.9 7.4 209.6 2.1 35.2 8.2 0.6 7.6 152.4 15.5 20.1 0.6 11.6 4.8 19.4 105.2 248.1 235.7 7.4 88.6 2.7 44.8 2.7 15.5 9.6 2.0 2.6 FILIP1L "DOC-1, GIP130" ENSG00000168386 "Filamin A interacting protein 1 like" Q4L180 3 99830141-100114513 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 210.1;Early spermatids: 376.7;Sertoli cells: 256.4;Skeletal myocytes: 184.2;Smooth muscle cells: 351.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Group enriched" "Detected in many" 4 "dendritic cells: 2.1;monocytes: 2.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 84.2;HDLM-2: 79.9;TIME: 145.8" "Region enriched" "Detected in many" 7 "olfactory bulb: 18.0" "Low region specificity" "Detected in all" HPA043133 Approved Approved "Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA043133: AB_10793991" "unprognostic (9.14e-2)" "unprognostic (2.16e-1)" "unprognostic (7.73e-2)" "unprognostic (5.25e-2)" "unprognostic (6.68e-2)" "unprognostic (1.06e-2)" "unprognostic (4.40e-2)" "unprognostic (1.29e-1)" "unprognostic (2.08e-2)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (3.32e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (2.46e-2)" "unprognostic (9.44e-2)" "unprognostic (5.30e-2)" "unprognostic (1.82e-3)" 77.1 21.7 4.9 52.4 6.3 0.8 32.6 4.8 6.6 63.8 4.0 57.7 28.4 117.6 23.8 56.0 31.2 90.9 54.8 6.2 4.4 24.0 28.1 30.7 30.1 9.6 4.2 76.4 35.5 17.5 3.9 43.9 9.7 67.9 29.8 4.7 9.3 54.3 140.4 16.8 41.2 151.7 3.7 42.9 46.7 22.0 3.6 11.9 20.1 161.5 22.3 101.5 21.9 4.0 59.0 0.0 22.3 0.1 35.8 30.2 2.0 29.4 58.8 50.2 56.5 17.8 0.2 0.2 5.0 84.2 13.2 7.1 0.0 14.4 59.0 79.9 0.6 4.8 0.2 23.3 17.8 1.4 0.0 24.2 5.1 5.6 0.0 32.0 22.8 0.0 3.8 0.5 7.7 0.1 5.2 1.2 1.3 3.1 0.0 0.1 26.1 0.7 33.5 1.0 2.0 3.7 0.4 0.4 0.1 11.7 0.0 10.5 145.8 8.8 0.2 1.9 15.5 4.2 0.2 0.3 6.5 0.4 0.0 0.2 0.4 0.0 0.1 1.0 0.0 0.6 0.1 0.1 2.1 0.6 0.0 0.1 0.2 0.4 2.9 0.4 0.1 0.3 4.9 6.3 4.8 6.6 6.2 4.4 9.6 4.2 9.7 3.7 3.6 4.0 92.9 16.0 23.1 9.4 4.1 27.8 56.7 7.9 2.2 11.8 12.3 6.5 145.7 35.8 2.3 5.5 8.4 1.1 1.8 2.1 1.9 210.1 376.7 2.3 60.5 77.2 3.0 0.0 42.0 109.3 0.7 145.2 21.9 2.4 34.8 16.3 41.0 0.7 3.2 106.0 25.8 5.7 6.1 36.3 98.9 180.2 83.0 86.1 17.8 25.3 17.7 0.9 0.0 22.1 21.6 43.7 0.2 104.2 3.0 5.1 5.4 2.6 1.9 6.0 256.4 184.2 351.9 40.1 2.5 1.5 22.7 3.1 8.8 41.8 3.2 3.5 FKBP10 "FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FKBP prolyl isomerase 10" Q96AY3 17 41812680-41823213 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 79.1;Fibroblasts: 100.0;Sertoli cells: 59.2;Smooth muscle cells: 65.3;Theca cells: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 551.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" 39.4 39.5 20.9 27.1 22.2 0.5 33.5 21.7 26.1 64.0 22.0 29.1 7.6 61.5 16.9 13.9 50.9 46.0 45.6 20.3 22.1 17.7 7.8 37.8 10.9 24.6 21.6 58.4 15.1 48.5 56.7 60.7 22.2 32.6 10.8 6.0 14.7 30.8 7.6 20.4 19.1 55.6 21.9 14.3 18.5 9.0 24.2 4.9 34.9 9.3 4.4 42.2 39.1 21.6 0.7 119.6 110.7 363.3 379.3 441.7 92.0 490.4 497.4 185.6 159.0 62.1 4.8 0.3 6.6 551.9 45.9 0.8 66.7 133.4 77.9 33.0 99.9 48.6 132.1 181.0 411.4 0.0 0.6 476.1 0.5 150.3 115.5 352.6 158.8 0.0 1.9 16.7 157.0 163.2 0.3 0.1 85.4 258.0 38.3 9.9 125.2 15.7 31.7 0.1 26.7 92.1 0.7 349.3 166.0 137.4 54.1 3.1 181.0 219.0 111.5 145.8 76.0 0.8 0.2 0.3 299.7 0.0 213.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.9 22.2 21.7 26.1 20.3 22.1 24.6 21.6 22.2 21.9 24.2 21.6 14.9 0.0 4.8 38.2 0.2 8.5 11.5 2.7 1.2 0.6 10.8 13.2 2.3 1.5 1.4 0.0 0.0 6.1 0.2 0.1 0.0 8.7 0.7 3.0 79.1 34.9 0.0 0.0 0.3 4.7 30.8 100.0 1.5 4.6 0.0 32.9 30.4 0.0 4.7 15.2 0.3 1.3 0.0 0.0 9.7 2.9 46.9 1.5 16.0 15.0 0.0 32.0 0.0 17.1 0.1 2.2 0.1 44.8 0.5 8.2 0.0 0.0 0.1 1.1 59.2 35.2 65.3 0.9 7.6 0.5 5.1 11.9 2.1 54.0 0.6 1.6 FLNC "ABP-280, ABPL, FLN2" ENSG00000128591 "Filamin C" Q14315 7 128830406-128859274 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 635.2;skeletal muscle: 1384.8;tongue: 442.6" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 1892.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 393.6;fHDF/TERT166: 180.2;hTEC/SVTERT24-B: 190.6;U-2 OS: 163.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006135, HPA071007" Enhanced Supported "Plasma membrane,Cytosol" NA NA 26000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA006135: AB_1848602, HPA071007: " "unprognostic (1.25e-1)" "unprognostic (7.38e-2)" "unprognostic (4.47e-2)" "unprognostic (1.40e-2)" "prognostic unfavorable (2.80e-4)" "unprognostic (1.64e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (2.17e-5)" "unprognostic (1.03e-3)" "unprognostic (2.35e-2)" "unprognostic (1.35e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (5.68e-3)" "unprognostic (1.15e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (3.73e-5)" 13.1 3.4 5.8 25.9 11.5 0.0 5.9 11.5 9.9 16.9 3.0 215.4 9.4 96.6 4.6 40.3 35.4 13.8 635.2 5.9 16.7 2.8 1.1 12.5 0.6 52.1 11.1 9.4 2.1 3.2 1.6 2.4 29.9 71.1 9.8 0.5 16.5 100.7 1384.8 8.9 40.3 114.4 51.7 0.7 65.6 2.2 19.1 0.3 4.3 442.6 0.2 162.7 21.3 49.8 0.1 0.8 4.2 0.1 34.4 41.2 4.1 393.6 73.6 109.2 52.3 124.0 1.0 0.1 64.7 180.2 44.9 0.1 23.7 0.9 64.4 0.2 13.1 0.1 20.2 0.1 43.2 0.0 0.2 78.0 0.1 190.6 0.1 44.2 69.0 0.3 49.0 0.2 75.8 0.0 0.0 1.5 64.5 0.1 22.6 0.1 127.5 1.0 0.1 0.0 2.1 7.0 0.7 0.1 0.3 88.0 0.4 1.6 144.6 38.2 163.5 10.1 0.2 0.1 0.0 0.3 129.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 11.5 11.5 9.9 5.9 16.7 52.1 11.1 29.9 51.7 19.1 49.8 3.6 3.2 0.5 0.7 0.0 3.7 0.3 0.1 1.2 0.6 0.3 1.3 1892.3 0.0 1.9 1.8 0.0 0.4 0.2 0.5 0.0 0.7 0.4 1.8 5.0 31.4 0.0 0.0 0.2 0.2 3.0 31.6 0.0 2.9 0.0 0.6 1.8 0.0 0.9 0.0 1.1 0.3 0.0 0.0 6.9 0.9 5.3 0.5 5.4 0.0 0.0 0.1 0.0 0.0 5.8 2.6 0.1 10.5 1.2 2.7 0.0 1.1 0.0 0.2 0.0 71.8 38.1 0.3 1.0 0.2 4.5 1.9 1.0 0.1 0.2 1.0 FMN2 ENSG00000155816 "Formin 2" Q9NZ56 1 240014348-240475187 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, Protein transport, Stress response, Transport" "Actin-binding, Developmental protein" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.0;parathyroid gland: 19.7;retina: 16.7" "Cell type enhanced" "Detected in many" "Astrocytes: 758.1;Excitatory neurons: 537.5;Horizontal cells: 124.5;Inhibitory neurons: 366.7;Oligodendrocyte precursor cells: 154.3" "Group enriched" "Detected in some" 8 "glioma: 5.9;testis cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.8;BJ hTERT+: 39.4;fHDF/TERT166: 73.8;LHCN-M2: 87.9;U-138 MG: 48.9;WM-115: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050649 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Actin filaments" "HPA050649: AB_2681202" "unprognostic (1.55e-2)" "unprognostic (8.21e-2)" "unprognostic (4.01e-2)" "unprognostic (8.06e-2)" "unprognostic (2.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.97e-3)" "unprognostic (2.11e-2)" "unprognostic (2.93e-1)" "unprognostic (3.92e-2)" "unprognostic (3.35e-3)" "unprognostic (4.08e-1)" "unprognostic (1.11e-2)" "unprognostic (8.03e-3)" "unprognostic (9.78e-2)" "unprognostic (3.10e-2)" "unprognostic (1.40e-3)" 1.2 5.1 27.6 0.2 29.6 0.0 0.5 11.8 46.0 0.4 0.0 6.8 0.2 1.4 0.9 0.7 1.9 1.2 0.1 28.4 20.9 3.6 0.0 0.3 0.0 21.2 29.7 2.4 1.0 19.7 9.0 0.2 14.4 1.6 1.6 16.7 0.3 2.6 0.1 0.2 0.9 1.7 16.0 0.2 0.7 2.2 39.0 0.0 0.5 0.2 0.1 0.3 0.3 30.9 0.0 2.1 6.6 0.0 20.2 15.3 0.0 70.8 39.4 31.0 16.3 0.0 0.0 0.0 0.0 73.8 1.2 0.0 1.3 0.0 28.8 0.0 5.8 0.0 0.7 0.0 0.1 0.0 0.0 1.7 0.0 8.5 1.9 17.0 0.0 0.0 0.0 0.0 87.9 0.0 0.0 0.1 2.3 0.0 2.2 0.0 0.2 0.0 0.0 0.0 12.0 10.6 0.0 0.1 0.3 0.2 2.1 0.1 0.3 48.9 0.2 16.0 18.2 0.0 0.0 0.0 10.4 0.0 69.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.6 29.6 11.8 46.0 28.4 20.9 21.2 29.7 14.4 16.0 39.0 30.9 0.0 0.0 0.0 758.1 0.0 0.1 0.0 0.0 0.0 30.6 0.2 0.3 1.6 0.0 0.0 1.8 50.1 0.1 0.0 4.7 0.0 0.0 15.2 4.3 0.7 0.5 12.1 0.0 537.5 0.0 0.1 1.4 0.0 1.1 0.0 0.8 2.9 0.1 0.1 124.5 366.7 0.5 0.0 0.6 0.6 3.0 0.3 0.1 1.8 31.9 0.0 2.3 0.0 154.3 17.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.3 1.8 4.4 0.0 0.0 0.5 0.0 3.1 1.6 0.0 FNDC3A "bA203I16.5, FNDC3, KIAA0970" ENSG00000102531 "Fibronectin type III domain containing 3A" Q9Y2H6 13 48975912-49209779 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008927, HPA012555, HPA012825" Approved Approved "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Golgi apparatus, Centrosome" Cytosol "HPA008927: AB_1078899, HPA012555: , HPA012825: AB_1848985" "unprognostic (1.54e-1)" "unprognostic (1.34e-3)" "unprognostic (8.83e-2)" "unprognostic (1.04e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (2.91e-2)" "unprognostic (5.71e-2)" "unprognostic (6.17e-2)" "unprognostic (3.16e-2)" "unprognostic (1.87e-2)" "unprognostic (4.03e-2)" "prognostic favorable (4.25e-4)" "unprognostic (8.93e-3)" "unprognostic (1.03e-1)" "unprognostic (9.60e-2)" "unprognostic (6.14e-2)" 17.8 39.9 15.2 18.7 18.6 17.0 26.3 12.7 16.4 35.2 13.6 23.3 27.5 32.1 38.8 13.1 26.5 26.8 14.0 15.3 39.4 29.7 66.9 21.6 16.7 16.7 19.6 35.4 43.1 27.7 30.8 44.1 17.4 22.1 24.0 21.9 36.8 33.9 10.1 11.4 23.8 26.0 15.5 22.6 28.8 30.4 31.9 21.3 51.2 13.1 18.9 25.6 14.1 17.9 11.6 13.1 47.1 12.4 58.3 73.0 9.2 53.3 70.8 50.2 36.3 17.9 27.7 8.8 9.7 40.5 21.8 12.4 28.4 18.1 72.6 22.1 21.9 14.3 36.9 33.2 35.3 13.4 2.3 37.7 24.8 44.7 51.4 47.1 52.6 11.9 18.0 21.0 55.4 4.7 13.3 26.7 23.2 25.0 11.0 12.6 18.8 16.4 42.4 21.2 17.8 29.4 20.1 17.8 38.8 29.8 9.6 26.0 41.7 26.1 17.9 24.3 38.3 25.4 14.4 8.1 19.6 16.9 27.4 1.9 3.0 1.9 2.5 2.0 3.6 3.3 2.9 2.2 1.9 2.2 3.7 3.3 4.5 2.1 4.0 4.0 2.6 1.7 15.2 18.6 12.7 16.4 15.3 39.4 16.7 19.6 17.4 15.5 31.9 17.9 46.7 54.5 49.0 88.2 36.2 18.4 37.4 17.5 44.3 52.0 33.4 25.5 27.1 27.1 28.9 36.8 37.5 13.2 36.4 21.6 13.7 30.6 45.9 42.1 74.3 42.4 43.5 17.9 159.5 36.2 38.2 58.0 57.6 56.4 31.6 38.8 32.9 74.2 25.4 35.3 170.8 37.4 18.3 31.8 24.4 13.1 33.8 45.5 37.4 112.4 27.0 52.7 24.7 177.9 178.2 25.5 29.0 39.5 165.9 44.2 37.8 48.0 35.6 42.5 6.6 48.0 50.8 89.8 33.7 20.3 11.9 32.3 30.9 46.4 24.7 26.4 FOXF1 "FKHL5, FREAC1" ENSG00000103241 "Forkhead box F1" Q12946 16 86510527-86515422 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 61.2;urinary bladder: 49.9" "Group enriched" "Detected in some" 4 "Endothelial cells: 17.1;Fibroblasts: 46.3;Smooth muscle cells: 18.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ: 12.8;BJ hTERT+: 27.9;HHSteC: 26.5;U-2197: 11.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028886 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA028886: AB_10601652" "unprognostic (7.91e-2)" "unprognostic (3.02e-3)" "unprognostic (1.23e-1)" "unprognostic (4.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.62e-3)" "unprognostic (2.37e-2)" "unprognostic (1.08e-1)" "unprognostic (8.22e-2)" "unprognostic (6.07e-3)" "unprognostic (1.06e-1)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (4.89e-2)" "unprognostic (4.20e-2)" "unprognostic (7.11e-2)" "unprognostic (2.44e-1)" 3.6 0.2 6.0 10.2 5.3 0.0 1.2 4.8 5.4 16.2 2.9 61.2 8.9 2.7 1.1 10.1 1.8 15.0 0.8 4.5 4.8 2.1 3.2 34.1 3.2 5.9 5.2 0.7 1.3 1.1 0.4 23.1 6.0 25.8 10.8 0.2 1.2 5.4 0.2 0.3 21.2 11.7 5.1 0.6 26.3 0.7 7.0 0.1 5.4 1.4 1.5 49.9 11.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 27.9 3.8 1.3 0.0 0.1 0.0 0.0 1.2 2.6 0.0 2.2 0.0 3.3 0.0 1.5 0.0 2.1 0.0 26.5 0.0 2.3 2.8 0.0 4.5 0.5 0.4 4.7 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 4.4 0.8 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.6 0.1 0.0 0.0 0.0 1.9 11.9 0.0 0.0 0.0 0.0 2.5 0.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 5.3 4.8 5.4 4.5 4.8 5.9 5.2 6.0 5.1 7.0 5.1 2.0 0.0 0.6 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.4 0.3 17.1 0.0 0.0 0.0 0.0 0.4 46.3 1.1 0.2 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.3 0.2 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.0 0.0 0.0 0.0 0.4 0.0 0.1 18.7 0.0 1.3 0.6 0.3 1.2 0.1 0.1 0.0 0.6 FOXF2 "FKHL6, FREAC2" ENSG00000137273 "Forkhead box F2" Q12947 6 1389576-1395603 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.2" "Cell type enhanced" "Detected in some" "Endothelial cells: 5.2;Fibroblasts: 7.9;Microglial cells: 19.7;Smooth muscle cells: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 70.4;HEK 293: 24.3;U-2197: 28.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.14e-2)" "unprognostic (2.03e-1)" "unprognostic (8.33e-2)" "unprognostic (1.68e-1)" "unprognostic (5.39e-2)" "unprognostic (3.32e-2)" "unprognostic (8.12e-2)" "unprognostic (1.11e-1)" "unprognostic (9.89e-3)" "unprognostic (2.53e-1)" "unprognostic (4.50e-2)" "unprognostic (8.76e-2)" "unprognostic (8.75e-7)" "unprognostic (1.03e-1)" "unprognostic (4.74e-2)" "unprognostic (2.08e-2)" "unprognostic (8.29e-2)" 1.8 0.4 8.1 1.8 6.0 0.0 2.4 5.5 10.3 1.0 5.1 40.2 6.0 0.2 0.8 9.6 0.5 1.5 0.7 6.1 5.2 0.2 0.1 17.8 0.4 10.1 6.0 0.1 1.0 0.6 7.6 9.1 10.0 10.8 9.3 0.1 1.3 0.6 1.0 1.4 18.7 3.5 5.1 0.0 17.8 0.9 7.1 0.0 3.7 3.5 1.8 11.1 2.1 6.9 1.6 3.4 1.0 0.8 3.2 4.9 0.1 15.6 70.4 6.3 2.9 0.3 0.0 0.0 3.3 4.6 6.8 11.9 12.2 0.6 2.8 0.0 24.3 0.0 5.7 0.0 6.1 0.0 0.4 0.8 5.0 0.0 5.9 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.1 0.1 0.0 0.0 0.0 6.9 0.2 0.0 3.7 0.0 5.2 1.3 0.0 0.2 0.0 5.8 11.0 28.7 2.8 0.3 0.0 0.0 0.0 4.7 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 6.0 5.5 10.3 6.1 5.2 10.1 6.0 10.0 5.1 7.1 6.9 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.0 5.2 0.0 0.0 1.1 0.0 1.5 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.4 2.5 0.1 1.8 19.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.6 5.5 0.2 1.5 0.3 0.1 0.1 0.1 0.0 0.0 0.0 FRMD6 "C14orf31, EX1, MGC17921, willin" ENSG00000139926 "FERM domain containing 6" Q96NE9 14 51489100-51730727 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 160.6;Early spermatids: 219.1;Late spermatids: 473.0;Suprabasal keratinocytes: 137.5;Urothelial cells: 130.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 351.1;fHDF/TERT166: 765.6;U-138 MG: 290.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001297 Uncertain Supported Approved Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA001297: AB_1078913" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-1)" "unprognostic (2.64e-2)" "unprognostic (8.05e-2)" "unprognostic (8.19e-2)" "unprognostic (3.55e-3)" "unprognostic (1.28e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.66e-4)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.28e-4)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.18e-1)" "unprognostic (2.11e-2)" "unprognostic (1.20e-2)" 12.1 13.4 5.2 9.5 5.2 1.2 27.1 12.6 6.7 28.1 8.4 16.0 5.2 53.6 11.3 59.8 13.4 33.0 7.3 6.4 4.5 4.2 10.4 8.6 5.5 5.7 8.1 25.9 5.0 2.4 3.4 14.1 4.9 27.7 10.8 1.5 21.5 30.7 7.4 43.2 7.5 46.8 5.4 12.0 7.2 31.0 5.8 12.6 6.6 6.8 12.7 31.5 30.1 5.6 71.4 14.1 20.1 42.1 40.1 67.6 8.8 351.1 163.2 169.5 146.0 51.9 16.4 1.9 10.6 765.6 47.6 82.8 5.7 113.8 200.3 1.1 8.6 0.3 7.6 2.2 46.8 0.2 4.2 58.8 40.9 152.0 200.5 77.8 52.6 3.7 0.7 24.6 181.8 12.2 7.1 0.2 3.9 0.2 27.4 0.8 79.1 0.7 33.4 113.7 4.1 44.9 27.8 3.9 31.3 37.7 3.0 1.0 242.6 290.7 97.6 73.3 73.5 18.9 17.3 0.2 19.3 0.3 114.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.1 0.0 0.0 0.1 5.2 5.2 12.6 6.7 6.4 4.5 5.7 8.1 4.9 5.4 5.8 5.6 6.9 3.2 1.5 34.6 0.8 111.4 160.6 42.4 41.5 0.4 40.5 49.4 2.9 8.6 11.6 0.0 0.0 40.1 1.5 0.0 0.0 16.9 219.1 2.0 41.1 14.4 0.0 2.5 45.2 2.9 4.8 57.8 1.1 3.6 1.3 0.9 9.3 4.2 3.8 0.0 22.5 0.3 10.2 0.3 21.1 473.0 17.7 1.5 32.0 68.4 0.7 8.2 0.0 74.9 5.9 64.0 0.0 22.2 3.7 52.0 0.1 0.4 2.7 0.5 6.6 24.5 28.0 10.2 9.8 115.7 137.5 39.0 3.3 0.9 0.1 130.7 FSTL1 "FRP, FSL1, OCC-1, OCC1, tsc36" ENSG00000163430 "Follistatin like 1" Q12841 3 120392293-120450993 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 352.1;Fibroblasts: 521.9;Leydig cells: 327.4;Peritubular cells: 270.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 12.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 12.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 1782.4;BJ: 2156.3;fHDF/TERT166: 2692.9;HBF TERT88: 1741.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035251, HPA040815" Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 34000000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA035251: AB_10601906, HPA040815: AB_2732489" "unprognostic (2.60e-1)" "unprognostic (1.59e-3)" "unprognostic (8.84e-2)" "unprognostic (4.54e-3)" "unprognostic (4.10e-2)" "unprognostic (1.35e-1)" "unprognostic (9.88e-2)" "unprognostic (3.05e-2)" "unprognostic (1.19e-2)" "unprognostic (3.88e-2)" "unprognostic (3.54e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (4.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.05e-2)" "unprognostic (4.47e-3)" 432.4 134.3 20.5 116.3 18.1 2.2 166.1 22.8 22.7 279.9 83.0 156.4 37.1 157.5 50.8 126.1 150.6 257.0 242.7 20.6 22.8 45.4 35.7 120.7 50.3 28.5 44.6 90.3 37.3 35.5 25.7 442.0 23.1 188.3 90.4 29.8 59.3 184.4 31.8 64.2 69.1 409.6 22.7 63.1 68.6 33.5 22.7 24.2 78.8 89.8 38.8 260.4 104.3 20.6 81.0 21.2 222.9 91.8 1304.4 1782.4 1.3 2156.3 1208.9 1374.5 1211.0 0.1 178.5 0.8 178.8 2692.9 112.8 20.5 68.6 270.0 1741.5 1.1 32.5 0.4 159.8 0.3 286.0 1.2 0.9 1362.7 8.5 884.5 192.7 612.1 811.6 11.2 0.5 0.3 227.6 0.5 22.6 2.0 181.3 0.4 181.9 0.7 92.7 1.0 150.4 1.7 39.2 93.5 764.6 13.6 76.5 462.6 23.5 6.2 986.8 507.4 479.8 268.0 323.8 1.0 1.1 2.3 177.4 0.9 67.0 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 2.6 20.5 18.1 22.8 22.7 20.6 22.8 28.5 44.6 23.1 22.7 22.7 20.6 76.9 64.1 9.4 56.5 1.1 64.1 31.9 36.4 10.2 2.3 25.6 24.6 127.5 8.6 42.5 23.9 0.0 114.4 2.5 0.9 0.0 62.6 2.3 44.4 176.7 111.4 3.0 3.6 9.6 5.8 352.1 521.9 3.1 23.0 1.3 66.5 142.5 17.4 20.6 1.7 16.2 0.2 8.2 10.8 91.6 9.8 327.4 11.5 110.3 30.0 9.9 116.1 0.0 9.5 0.9 117.8 0.7 270.8 0.9 108.4 0.0 5.5 74.9 4.3 59.2 62.5 129.3 1.5 4.4 2.2 48.2 54.7 7.1 47.5 0.9 65.3 FUT11 MGC33202 ENSG00000196968 "Fucosyltransferase 11" Q495W5 10 73772276-73780251 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 171.6;Late spermatids: 234.7;NK-cells: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014033 Approved Approved "Nuclear membrane,Golgi apparatus" "Intracellular and membrane" NA NA 1200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Nuclear membrane" "Golgi apparatus" "HPA014033: AB_1849192" "prognostic unfavorable (6.78e-4)" "prognostic unfavorable (2.39e-6)" "unprognostic (1.47e-2)" "unprognostic (2.42e-3)" "unprognostic (3.27e-1)" "unprognostic (7.64e-2)" "unprognostic (2.29e-2)" "unprognostic (3.50e-3)" "unprognostic (1.51e-1)" "unprognostic (9.30e-2)" "unprognostic (9.77e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.67e-4)" "unprognostic (2.59e-2)" "unprognostic (1.71e-1)" "unprognostic (3.61e-1)" "unprognostic (2.66e-2)" 9.4 5.1 2.5 6.8 3.2 6.4 5.2 4.4 2.8 8.9 1.8 4.5 3.1 6.0 3.2 7.0 4.7 9.0 9.4 2.1 3.8 4.7 5.1 8.7 6.4 4.9 4.8 6.3 4.1 3.7 3.1 17.4 4.1 4.3 3.8 10.0 4.1 6.4 4.1 4.5 3.7 8.3 4.1 10.2 4.9 10.2 5.0 4.3 7.0 4.8 6.2 7.0 4.8 4.9 26.4 14.2 9.9 20.8 19.2 22.2 2.9 13.1 31.3 16.3 31.7 4.7 13.8 6.1 9.3 21.7 5.5 10.9 5.2 13.3 18.1 14.4 10.9 8.1 11.4 7.6 7.5 11.6 24.5 14.8 3.0 15.5 15.9 50.3 30.1 2.7 8.1 10.5 16.4 3.2 2.0 6.0 4.7 2.5 35.1 2.8 6.1 7.2 5.9 4.7 3.0 9.6 11.5 12.0 7.5 8.4 8.2 5.0 31.3 21.1 9.0 10.6 16.4 13.8 5.1 1.4 29.6 10.2 7.0 5.4 1.4 1.4 20.0 1.6 14.2 2.1 5.9 14.3 1.7 1.8 4.3 8.9 0.3 10.9 1.8 3.5 2.6 6.9 2.5 3.2 4.4 2.8 2.1 3.8 4.9 4.8 4.1 4.1 5.0 4.9 22.4 16.0 13.1 6.2 12.1 13.6 5.6 22.7 5.2 14.6 6.1 6.1 12.2 7.2 9.8 11.0 14.6 10.7 23.1 4.9 0.0 13.3 171.6 6.7 12.0 28.0 4.8 15.8 6.0 6.8 25.2 15.8 2.6 10.5 14.0 7.1 38.2 5.2 12.5 20.2 5.7 4.6 2.0 18.1 16.7 234.7 16.1 11.0 17.8 11.2 11.4 8.3 69.0 5.0 6.5 10.3 5.2 14.7 10.2 8.9 2.6 3.4 9.8 13.0 6.6 14.3 11.7 20.7 19.0 5.5 11.5 9.7 19.9 6.8 3.1 6.4 FZD2 ENSG00000180340 "Frizzled class receptor 2" Q14332 17 44557484-44561262 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 10.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Kupffer cells: 9.8;Leydig cells: 23.3;Peritubular cells: 18.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;myeloid DC: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;monocytes: 1.1" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 53.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057667 Uncertain Approved "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "Cell Junctions" "HPA057667: AB_2683497" "unprognostic (6.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.04e-2)" "unprognostic (8.83e-3)" "unprognostic (2.04e-1)" "unprognostic (5.29e-3)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (9.45e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-2)" "unprognostic (1.86e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-2)" "unprognostic (6.35e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-3)" 1.5 1.6 1.0 1.4 1.5 0.2 1.3 0.9 1.2 5.9 10.5 1.8 0.9 5.3 1.3 0.9 3.8 1.8 2.8 1.1 1.3 2.8 0.2 2.9 0.8 1.3 1.9 3.3 1.5 2.1 1.1 3.6 2.0 1.7 0.4 0.7 1.0 1.9 0.4 0.6 1.6 1.5 1.3 2.1 1.2 1.5 1.4 0.3 2.4 0.7 0.7 2.0 2.5 1.6 12.9 37.7 38.3 13.8 8.7 6.4 0.4 39.5 30.4 53.4 38.2 28.4 6.2 0.0 8.9 13.9 13.1 5.5 3.6 2.8 30.2 2.9 7.2 1.7 6.6 0.1 7.7 0.2 7.5 10.7 2.8 9.6 8.8 40.8 1.8 4.9 2.5 0.3 20.9 5.9 6.7 3.6 26.8 0.1 6.7 18.1 8.6 1.9 7.7 0.6 3.8 10.9 5.2 1.1 2.3 32.4 14.6 8.4 0.7 24.1 17.5 4.4 22.6 0.8 0.7 3.0 4.0 2.4 11.3 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.2 1.0 1.5 0.9 1.2 1.1 1.3 1.3 1.9 2.0 1.3 1.4 1.6 0.5 19.2 0.0 1.6 0.6 0.6 0.3 0.9 0.0 0.0 0.9 2.9 1.9 0.0 0.2 1.8 0.0 1.6 1.8 0.0 0.0 0.3 0.6 1.1 8.4 0.7 1.2 1.3 0.0 1.8 0.5 5.9 0.0 1.5 0.0 1.4 0.7 0.0 4.8 0.0 0.0 0.3 0.0 9.8 6.0 0.4 23.3 5.6 0.0 6.5 6.2 6.0 0.0 0.0 0.2 0.7 0.0 18.0 0.3 0.1 0.0 0.3 0.2 0.4 0.0 0.4 5.3 0.3 1.2 0.3 0.4 2.3 0.2 2.4 0.0 0.0 FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202033855-202038441 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 30.9;Breast myoepithelial cells: 37.0;Cardiomyocytes: 21.1;Fibroblasts: 23.5;Proximal enterocytes: 21.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 30.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 42.8;BJ hTERT+: 48.4;CAPAN-2: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA059979: , HPA069165: AB_2686096, HPA076183: " "unprognostic (3.44e-2)" "unprognostic (6.89e-2)" "unprognostic (9.30e-3)" "unprognostic (2.44e-3)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.71e-5)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-3)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.16e-2)" "unprognostic (2.05e-3)" 10.2 3.0 4.9 5.6 4.7 0.4 15.5 30.2 4.3 13.2 6.3 36.7 6.9 18.4 14.1 9.4 16.8 6.3 14.4 8.8 5.0 8.2 1.2 5.3 3.9 5.2 4.9 25.0 1.7 1.1 9.3 5.7 5.5 19.2 5.5 1.3 21.7 23.5 26.7 10.9 10.8 11.1 4.9 1.9 5.9 2.1 4.5 1.1 5.1 9.5 3.8 27.1 15.3 5.6 10.3 5.2 33.2 10.8 10.6 7.9 14.8 42.8 48.4 11.9 13.9 32.2 62.7 0.1 25.1 26.2 7.9 10.6 6.0 1.3 13.7 5.4 8.6 1.1 2.1 2.7 7.2 2.1 2.1 7.6 1.0 6.4 3.7 9.5 0.0 0.7 2.9 2.6 9.8 4.2 0.0 5.7 36.6 2.0 3.5 4.2 6.4 1.1 1.9 6.1 5.5 12.6 5.4 0.4 6.8 26.7 3.8 2.5 0.1 23.8 8.8 15.0 5.4 2.7 2.2 0.1 4.9 0.5 16.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.7 30.2 4.3 8.8 5.0 5.2 4.9 5.5 4.9 4.5 5.6 3.5 0.0 8.1 3.6 2.0 10.3 8.3 1.9 14.8 0.0 30.9 37.0 21.1 1.5 0.3 1.8 0.0 0.5 2.0 4.7 1.9 1.6 0.1 1.5 2.0 1.7 1.2 0.0 1.5 0.2 1.1 23.5 2.6 3.6 1.3 7.5 0.7 0.7 1.5 0.0 0.2 9.9 0.0 0.8 5.7 0.5 5.3 2.0 3.6 0.0 0.1 7.5 0.0 0.0 0.1 0.6 2.1 4.9 1.7 6.9 21.3 0.1 0.9 0.6 6.6 13.5 16.3 1.6 2.9 11.4 9.8 0.8 2.5 0.5 7.6 1.8 GADD45B "DKFZP566B133, GADD45BETA, MYD118" ENSG00000099860 "Growth arrest and DNA damage inducible beta" O75293 19 2476122-2478259 "Predicted intracellular proteins" "Apoptosis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1997.9;Breast myoepithelial cells: 1851.8;Smooth muscle cells: 1753.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 16.3" HPA029816 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA029816: AB_10601325" "unprognostic (1.32e-1)" "unprognostic (4.51e-2)" "unprognostic (3.94e-3)" "unprognostic (5.06e-2)" "unprognostic (1.53e-2)" "unprognostic (3.09e-2)" "unprognostic (2.46e-3)" "unprognostic (2.02e-3)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" "unprognostic (2.95e-1)" "unprognostic (2.79e-1)" "unprognostic (4.37e-2)" "unprognostic (1.09e-3)" "unprognostic (3.90e-2)" "unprognostic (8.27e-3)" "unprognostic (6.00e-2)" 343.5 75.9 45.3 41.4 52.8 321.4 217.4 51.4 63.8 104.8 55.0 205.1 17.2 83.4 3.3 53.9 190.0 91.4 372.7 45.1 57.8 245.6 408.9 343.2 33.1 56.3 55.5 159.2 92.6 49.2 174.1 45.1 54.9 90.8 9.9 57.1 72.6 28.5 84.1 144.8 67.9 27.3 55.0 75.9 187.3 17.1 59.7 65.9 209.2 30.8 12.7 103.9 100.0 49.5 62.1 12.2 1.4 8.1 44.1 33.6 3.8 61.7 17.7 47.6 24.4 17.1 23.3 29.1 40.7 30.7 17.1 33.8 3.2 20.5 11.5 22.5 11.0 3.2 13.9 6.6 74.3 6.7 19.7 54.8 13.1 14.3 70.2 51.3 19.0 3.1 1.6 76.9 49.5 19.9 7.7 33.0 7.3 6.2 25.7 28.5 22.0 46.6 21.7 11.0 0.6 0.6 68.7 50.6 20.9 26.2 26.9 49.5 78.8 47.2 43.2 34.0 77.9 34.3 27.9 12.5 11.5 20.0 15.7 32.1 33.5 131.2 58.1 40.8 52.3 21.0 40.7 45.2 32.9 30.2 35.5 47.9 92.5 43.3 33.5 36.9 54.6 35.3 45.3 52.8 51.4 63.8 45.1 57.8 56.3 55.5 54.9 55.0 59.7 49.5 1997.9 423.1 571.3 24.5 450.9 341.7 805.4 147.3 376.2 11.9 666.3 1851.8 952.6 173.0 226.3 51.5 6.2 93.0 988.3 213.7 191.7 374.3 1.6 614.2 539.7 800.0 85.3 8.6 3.0 209.8 54.0 1143.0 400.1 1122.9 786.6 53.9 138.8 126.1 430.9 13.5 1.5 164.4 282.8 174.8 1169.6 4.7 74.0 863.0 517.6 1.9 157.1 269.8 33.0 0.5 0.9 292.5 309.0 29.3 416.8 823.3 294.3 142.1 211.4 34.2 177.5 818.8 1753.4 1.4 7.8 399.0 308.9 144.2 514.7 128.4 98.8 301.3 GALNT5 GalNAc-T5 ENSG00000136542 "Polypeptide N-acetylgalactosaminyltransferase 5" Q7Z7M9 2 157257705-157318491 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.5;lung: 10.2;stomach 1: 12.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.0;Distal enterocytes: 48.3;Intestinal goblet cells: 75.5;Pancreatic endocrine cells: 53.5;Prostatic glandular cells: 40.1;Urothelial cells: 115.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "cerebellum: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 45.3;BJ: 29.8;BJ hTERT+: 53.5;fHDF/TERT166: 64.5;HaCaT: 51.8;K-562: 30.7;LHCN-M2: 52.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008963, HPA009035" Approved Approved "Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA 1300000 "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Cytosol" "Nucleoli, Vesicles" "HPA008963: AB_1078942, HPA009035: AB_1078943" "unprognostic (6.34e-3)" "unprognostic (9.31e-2)" "unprognostic (2.11e-2)" "unprognostic (9.89e-2)" "unprognostic (3.19e-2)" "unprognostic (2.46e-2)" "unprognostic (4.63e-3)" "unprognostic (1.88e-1)" "unprognostic (1.09e-1)" "unprognostic (6.93e-2)" "unprognostic (4.01e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (6.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (9.48e-3)" 0.1 0.0 0.0 0.7 0.0 0.6 1.1 4.0 0.3 1.1 5.2 10.6 2.2 0.1 0.1 4.5 0.0 2.7 0.4 0.4 0.0 0.0 0.0 10.2 0.0 0.1 0.1 0.1 0.0 0.1 0.6 0.0 0.2 0.7 13.5 0.1 8.2 0.1 0.0 0.3 4.1 0.4 0.0 0.1 12.8 0.1 0.1 0.1 0.1 0.1 1.7 4.5 4.6 0.2 45.3 4.8 0.0 0.0 2.0 17.0 0.0 29.8 53.5 0.5 1.1 1.9 24.4 0.0 0.1 64.5 0.0 51.8 0.9 10.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 0.2 0.0 0.9 0.0 0.0 0.0 30.7 0.0 52.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 25.4 0.3 0.6 0.1 0.0 0.1 0.0 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.3 0.4 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.1 157.0 36.1 0.0 0.1 0.8 13.3 20.2 6.2 0.0 0.5 2.8 0.5 2.8 32.9 0.0 0.0 0.0 0.2 48.3 0.0 1.2 6.9 1.2 0.0 0.6 2.4 5.2 0.8 3.2 0.0 2.1 35.7 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 75.5 6.1 0.0 0.7 0.5 0.0 0.3 3.6 0.0 1.6 0.0 0.0 0.0 0.1 53.5 26.4 0.0 1.4 40.1 3.1 0.2 10.0 0.0 0.0 0.5 1.2 2.6 0.5 4.5 0.1 0.0 0.3 0.0 22.7 115.1 GAS6 "AXLLG, AXSF, DKFZp666G247, FLJ34709" ENSG00000183087 "Growth arrest specific 6" Q14393 13 113820549-113864076 "Predicted secreted proteins" "Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 348.3;Sertoli cells: 322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 70.7" "Lineage enriched" "Detected in many" 50 "dendritic cells: 70.7" "Cell line enhanced" "Detected in many" "BJ: 347.0;BJ hTERT+: 494.0;HSkMC: 281.3;RPMI-8226: 493.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008275, HPA056080" Approved Approved "Centriolar satellite,Cytosol" "Secreted to blood" NA NA 8900000 3600000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Centriolar satellite" "HPA008275: AB_1849497, HPA056080: AB_2683032" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.97e-3)" "unprognostic (1.37e-1)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (2.09e-2)" "unprognostic (2.92e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.55e-1)" "unprognostic (4.81e-3)" "unprognostic (1.97e-1)" "unprognostic (2.16e-2)" "unprognostic (9.00e-2)" "prognostic unfavorable (8.93e-6)" 124.2 32.5 26.7 18.8 28.7 3.6 77.4 33.9 32.0 244.4 59.3 67.8 48.7 171.7 13.8 63.2 161.3 58.9 169.1 24.1 34.6 72.7 37.1 97.3 22.5 37.4 36.1 118.0 49.9 58.5 58.4 51.6 38.5 100.9 25.2 6.3 84.4 63.8 99.2 101.4 47.8 57.9 30.8 29.4 70.0 60.1 34.1 39.6 101.2 67.5 10.6 127.0 172.0 25.2 151.3 6.6 4.4 3.8 169.5 94.0 18.4 347.0 494.0 141.3 168.4 9.6 71.0 1.4 11.4 157.2 24.9 139.1 2.4 77.7 35.6 0.2 20.1 1.1 11.1 1.0 120.8 1.0 2.1 281.3 44.9 39.1 39.0 243.2 5.3 2.3 2.6 79.9 231.9 7.4 0.8 1.5 9.5 24.0 9.9 4.5 0.1 493.5 51.9 1.9 23.5 21.3 38.3 1.3 0.4 23.8 45.9 119.4 81.7 36.9 45.0 4.4 100.5 0.1 8.0 1.5 41.9 3.6 5.8 0.0 1.4 0.0 0.0 1.1 0.0 0.1 0.2 0.0 11.3 0.1 0.0 0.0 0.0 0.1 0.3 70.7 0.0 1.4 26.7 28.7 33.9 32.0 24.1 34.6 37.4 36.1 38.5 30.8 34.1 25.2 133.2 198.7 25.9 23.2 20.8 84.4 94.7 18.5 70.0 38.0 17.9 114.3 86.8 50.1 23.4 31.3 0.0 1.8 59.1 92.4 27.4 45.7 5.1 35.2 33.1 71.9 10.3 5.3 26.2 6.7 1.9 152.7 19.9 32.3 8.2 154.7 159.9 21.6 101.6 348.3 31.9 69.5 8.2 22.3 100.4 8.9 92.2 48.6 122.7 41.2 9.8 32.7 0.0 3.0 7.5 24.1 58.6 59.5 147.4 30.5 84.1 0.6 15.5 12.5 322.1 22.9 121.1 5.3 17.6 27.6 71.9 2.9 4.7 214.8 151.4 31.1 GBP3 FLJ10961 ENSG00000117226 "Guanylate binding protein 3" Q9H0R5 1 89006679-89022894 "Predicted intracellular proteins" "Antiviral defense, Immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 78.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 127.2;Pancreatic endocrine cells: 106.7;Proximal enterocytes: 133.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 80.9;BJ hTERT+ SV40 Large T+ RasG12V: 56.3;LHCN-M2: 71.3" HPA045657 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA045657: AB_10961631" "unprognostic (1.14e-2)" "unprognostic (2.23e-1)" "unprognostic (6.30e-2)" "unprognostic (1.25e-1)" "unprognostic (4.06e-2)" "unprognostic (2.02e-1)" "unprognostic (2.18e-1)" "unprognostic (4.39e-2)" "unprognostic (3.47e-1)" "unprognostic (7.44e-2)" "unprognostic (4.42e-2)" "unprognostic (1.98e-1)" "unprognostic (1.86e-2)" "unprognostic (1.66e-2)" "unprognostic (9.70e-3)" "unprognostic (3.06e-2)" "unprognostic (5.06e-3)" 8.4 9.2 3.5 10.9 3.8 1.6 12.8 3.3 6.3 7.2 2.9 39.1 78.3 8.9 10.0 6.1 15.3 10.8 5.1 3.3 4.7 13.9 14.9 22.8 14.5 5.4 4.2 8.2 5.9 4.1 4.2 13.8 4.4 10.3 27.4 0.6 11.8 20.2 1.8 7.2 59.8 9.3 4.1 16.1 31.7 2.3 4.1 10.0 9.7 4.2 8.6 27.4 7.7 5.0 26.4 1.6 0.0 0.0 24.5 28.6 4.3 44.4 80.9 41.5 56.3 0.0 2.0 1.9 8.5 40.4 24.0 10.9 0.0 29.5 40.2 0.6 0.0 2.5 4.0 0.5 20.8 9.0 0.1 22.3 5.7 31.1 11.0 28.3 13.9 4.2 0.0 5.8 71.3 0.0 6.5 1.1 0.2 14.3 20.0 2.0 4.8 3.1 41.6 49.1 0.0 0.2 14.0 7.9 0.0 0.8 0.1 2.6 17.2 44.6 3.1 0.4 4.8 7.6 2.6 0.1 0.4 0.2 11.4 0.1 6.0 0.3 11.8 7.0 10.5 3.6 10.5 9.8 6.5 2.8 6.5 9.7 3.1 6.9 13.3 0.4 8.6 5.6 3.5 3.8 3.3 6.3 3.3 4.7 5.4 4.2 4.4 4.1 4.1 5.0 20.7 6.4 18.1 2.9 7.3 6.9 25.7 19.4 6.8 0.1 11.5 7.4 1.4 35.8 24.8 22.0 0.0 7.6 12.4 127.2 13.7 59.4 0.1 46.7 15.0 21.2 9.1 5.7 0.3 61.6 8.2 12.5 27.0 35.0 4.5 5.6 22.5 10.6 5.0 0.0 0.2 34.8 14.2 12.0 5.8 1.5 9.9 18.0 0.0 2.8 21.1 0.7 28.8 0.5 0.1 106.7 71.4 15.4 13.6 17.5 133.3 32.8 69.3 0.2 19.7 3.9 8.0 0.5 0.2 5.9 4.8 2.2 21.8 10.9 28.8 37.2 GFRA1 "GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1" ENSG00000151892 "GDNF family receptor alpha 1" P56159 10 116056925-116273284 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 40.5;Breast glandular cells: 33.1;Fibroblasts: 51.2;Hepatocytes: 42.2;Oligodendrocyte precursor cells: 91.0;Skeletal myocytes: 100.1" "Cancer enriched" "Detected in many" 11 "breast cancer: 40.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 44.7;BJ hTERT+ SV40 Large T+ RasG12V: 77.2;EFO-21: 46.5;fHDF/TERT166: 89.3;HBF TERT88: 63.2;MCF7: 59.5;U-251 MG: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043829 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 140000 "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA043829: AB_2678689" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (7.60e-2)" "unprognostic (1.06e-3)" "unprognostic (4.10e-2)" "unprognostic (6.95e-3)" "unprognostic (2.35e-3)" "unprognostic (1.48e-3)" "unprognostic (3.16e-1)" "unprognostic (2.06e-3)" "unprognostic (1.31e-2)" "unprognostic (2.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.20e-3)" "unprognostic (1.69e-1)" "unprognostic (2.27e-2)" "unprognostic (3.64e-2)" 10.9 3.4 7.2 4.2 14.9 0.0 23.2 2.6 9.5 9.9 0.3 18.3 1.7 4.9 20.5 6.9 17.2 5.6 4.8 9.7 18.0 6.0 16.0 2.8 4.0 7.8 28.5 4.5 6.6 2.7 3.2 0.0 7.2 4.5 3.9 3.2 6.0 5.4 4.3 7.2 8.2 4.8 6.2 3.9 8.2 3.1 7.6 4.1 2.8 13.9 6.4 7.0 9.2 6.1 0.1 3.7 12.2 0.0 0.0 0.1 0.0 7.9 0.4 44.7 77.2 0.0 0.0 0.0 46.5 89.3 0.0 0.0 0.1 0.0 63.2 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 2.5 0.0 11.5 0.0 3.9 0.0 9.1 0.0 0.0 5.6 59.5 7.6 0.0 5.0 0.0 0.0 0.0 1.9 0.0 5.0 0.0 1.6 0.1 0.0 0.0 0.1 2.1 0.4 0.0 0.4 0.0 0.4 0.1 53.5 0.0 0.0 0.1 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 14.9 2.6 9.5 9.7 18.0 7.8 28.5 7.2 6.2 7.6 6.1 6.1 0.0 0.0 40.5 0.5 5.7 0.0 0.0 1.8 4.1 33.1 11.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 13.2 0.0 0.2 3.2 6.0 0.0 5.1 13.5 0.0 51.2 3.1 0.0 6.3 0.1 0.4 42.2 0.0 0.0 6.6 0.0 0.0 1.0 9.6 12.8 8.1 1.0 5.4 1.9 0.0 12.6 0.0 91.0 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.9 0.0 0.5 0.0 100.1 16.7 0.1 10.4 0.7 4.5 0.0 0.7 0.1 0.0 0.2 GLIPR1 "GliPR, RTVP1" ENSG00000139278 "GLI pathogenesis related 1" P48060 12 75480753-75503863 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 216.3;Extravillous trophoblasts: 384.2;Hofbauer cells: 242.4;Kupffer cells: 273.9;Langerhans cells: 393.2;Macrophages: 259.6;monocytes: 220.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 189.3;U-138 MG: 363.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011014 Approved "Intracellular and membrane" NA NA 64000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA011014: AB_1849714" "unprognostic (2.32e-3)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (3.31e-1)" "unprognostic (2.32e-3)" "unprognostic (4.09e-1)" "unprognostic (7.58e-2)" "unprognostic (3.10e-1)" "unprognostic (7.23e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.69e-9)" "unprognostic (9.06e-3)" "unprognostic (5.08e-2)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" 17.2 16.9 2.0 47.0 1.7 18.3 11.5 1.5 5.6 15.6 3.8 11.4 6.6 32.6 6.0 7.9 17.9 33.5 9.2 2.3 2.8 5.6 12.5 22.1 32.7 4.0 3.3 13.7 3.7 2.3 3.9 25.8 3.9 9.2 12.6 1.7 9.7 17.1 3.1 3.4 14.1 39.9 3.4 36.4 10.8 4.8 4.2 19.8 5.4 7.3 32.3 35.0 6.7 8.4 7.2 7.0 5.9 0.6 22.0 46.2 0.9 93.0 97.5 76.8 55.7 3.8 2.7 23.9 19.1 101.7 67.6 1.2 0.2 38.6 124.7 38.0 1.6 1.2 8.4 6.1 25.1 8.4 1.3 43.0 14.1 189.3 41.4 123.1 62.0 1.7 1.7 29.0 144.7 0.1 4.0 20.2 0.6 0.2 2.8 1.0 4.5 0.8 8.1 1.6 0.2 0.2 38.5 0.3 0.2 12.5 0.9 6.7 102.6 363.8 35.4 39.2 144.1 5.1 0.8 2.1 144.4 9.9 5.6 25.3 352.7 40.9 115.0 232.6 77.2 73.9 80.5 90.7 240.2 90.2 24.3 50.4 462.1 20.4 265.6 202.1 91.2 265.0 2.0 1.7 1.5 5.6 2.3 2.8 4.0 3.3 3.9 3.4 4.2 8.4 6.5 12.8 16.0 2.0 121.6 13.6 189.2 23.0 4.0 2.9 15.5 19.9 0.9 5.7 10.0 3.7 4.2 4.8 216.3 0.3 0.0 102.8 14.3 11.3 119.4 7.0 3.5 11.8 13.3 83.9 384.2 46.1 2.0 16.4 10.1 0.8 10.4 4.4 242.4 6.7 14.6 0.4 4.1 273.9 393.2 5.9 14.3 259.6 16.0 28.1 220.9 1.4 123.6 2.5 1.5 90.9 2.5 53.8 66.8 106.5 0.1 1.5 10.6 3.2 13.1 8.1 50.2 7.9 1.0 4.6 9.8 16.8 161.9 26.7 0.6 42.8 GMFB GMF ENSG00000197045 "Glia maturation factor beta" P60983 14 54474484-54489026 "Plasma proteins, Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 90.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002954 Approved Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA002954: AB_1078997" "unprognostic (7.93e-2)" "unprognostic (7.69e-3)" "unprognostic (4.81e-3)" "unprognostic (2.99e-2)" "unprognostic (1.12e-2)" "unprognostic (2.06e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.48e-2)" "unprognostic (1.90e-1)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "prognostic favorable (9.48e-5)" "unprognostic (1.80e-1)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (9.09e-2)" 25.2 21.8 62.8 23.5 68.8 28.8 26.0 61.6 90.4 18.6 39.8 35.0 33.5 19.3 14.0 15.8 14.2 16.5 17.2 61.4 75.6 33.6 25.8 24.2 25.3 73.0 64.5 16.1 12.8 20.1 12.3 26.5 71.4 14.8 35.2 18.4 10.7 12.9 7.0 13.7 29.5 18.2 84.0 18.4 19.0 11.1 71.9 16.2 21.9 10.2 24.4 22.3 11.4 85.3 92.7 36.9 71.8 53.2 75.8 94.5 53.9 93.2 67.9 66.2 82.1 42.6 79.4 85.2 42.4 92.0 39.5 33.4 73.7 64.0 104.4 30.9 25.4 42.5 37.4 39.9 64.7 59.9 35.5 72.0 58.8 57.1 56.0 67.9 60.8 38.4 31.4 28.8 106.1 45.7 36.8 22.9 46.4 52.1 38.9 36.9 84.7 24.4 84.4 86.3 42.4 65.5 64.6 54.4 71.4 59.0 59.8 46.4 48.1 94.9 71.9 48.7 58.4 10.4 19.4 52.0 80.0 36.3 61.5 6.8 10.2 9.1 5.0 13.3 7.0 6.6 5.9 5.1 12.6 7.8 6.2 6.6 16.1 8.0 14.0 4.4 8.5 6.2 62.8 68.8 61.6 90.4 61.4 75.6 73.0 64.5 71.4 84.0 71.9 85.3 23.3 25.6 16.2 8.1 39.3 59.9 50.2 33.6 48.9 18.4 28.0 18.0 17.3 20.0 22.6 25.8 4.2 39.3 33.7 61.8 21.5 38.7 27.3 21.5 29.5 22.2 29.9 14.5 16.8 23.3 84.5 35.1 23.9 36.1 21.6 25.4 16.8 24.5 45.4 21.9 13.6 33.6 26.4 34.6 36.4 7.5 20.2 43.0 46.2 8.4 37.8 25.7 25.7 14.1 16.5 37.3 32.1 15.8 16.9 56.0 26.0 60.5 16.4 15.4 13.1 77.0 54.5 16.0 11.4 33.5 43.8 58.3 26.2 18.8 36.2 56.2 GNA11 "FBH, FBH2, FHH2, HHC2" ENSG00000088256 "G protein subunit alpha 11" P29992 19 3094362-3123999 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Transducer "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 330.6;Proximal enterocytes: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048886 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" "HPA048886: AB_2680544" "unprognostic (4.64e-3)" "unprognostic (2.21e-1)" "unprognostic (3.12e-1)" "unprognostic (2.23e-2)" "unprognostic (1.30e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.56e-2)" "unprognostic (1.40e-1)" "unprognostic (6.26e-2)" "unprognostic (7.85e-3)" "unprognostic (2.43e-1)" "prognostic favorable (1.48e-11)" "unprognostic (1.05e-2)" "unprognostic (1.01e-1)" "unprognostic (2.47e-1)" "unprognostic (3.02e-1)" 33.5 32.5 36.4 16.2 31.2 8.3 32.6 53.8 35.3 31.7 18.9 66.7 117.5 42.4 12.7 28.7 44.5 20.0 51.7 33.5 27.3 40.4 26.2 34.7 7.5 30.3 29.6 32.5 33.9 26.3 29.8 22.3 28.6 40.4 38.7 11.0 33.3 47.1 54.2 34.4 139.3 28.7 26.6 21.4 34.9 50.6 31.3 8.5 32.9 39.2 7.0 38.8 27.0 31.1 56.1 31.2 27.9 48.5 41.7 28.4 30.9 53.8 53.7 71.8 57.8 41.7 27.3 12.0 29.2 76.4 43.6 39.0 37.8 42.7 44.3 30.1 21.9 3.3 35.7 23.6 42.2 3.8 11.8 36.9 36.8 48.4 29.2 36.9 57.8 3.4 27.8 1.9 49.1 25.8 3.0 14.4 20.5 38.4 29.4 23.2 26.4 11.9 33.8 40.8 66.0 40.7 38.3 45.2 27.2 18.9 33.3 7.9 50.0 45.7 33.3 85.4 73.5 1.3 3.9 7.9 33.0 2.9 52.3 2.5 1.4 0.3 0.7 0.7 0.8 0.9 0.5 0.6 0.2 1.1 1.2 0.9 5.1 0.5 1.5 2.3 0.1 0.3 36.4 31.2 53.8 35.3 33.5 27.3 30.3 29.6 28.6 26.6 31.3 31.1 62.3 32.1 24.1 5.2 3.5 32.6 9.5 15.4 13.6 22.7 43.2 47.9 17.8 35.8 12.6 27.6 37.5 13.2 2.4 330.6 7.9 21.4 45.2 26.9 23.0 33.9 54.6 5.2 8.8 25.4 13.5 25.3 29.6 26.1 4.5 24.1 58.2 28.5 9.0 45.4 11.3 84.1 26.4 9.1 16.4 20.0 50.1 5.1 23.2 11.2 1.1 29.0 0.0 7.1 14.1 36.1 96.0 80.5 1.2 16.0 323.0 18.9 35.4 15.8 19.7 28.5 30.5 23.7 8.9 20.6 41.2 20.4 2.0 22.1 94.9 13.4 GNPTAB "GNPTA, KIAA1208, MGC4170" ENSG00000111670 "N-acetylglucosamine-1-phosphate transferase subunits alpha and beta" Q3T906 12 101745499-101830959 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Cancer-related genes, Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 192.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014558, HPA042343" Approved Supported "Golgi apparatus" NA NA 160000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "HPA014558: AB_2732409, HPA042343: " "unprognostic (6.72e-2)" "unprognostic (1.66e-1)" "unprognostic (8.71e-3)" "prognostic favorable (8.48e-4)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (2.73e-1)" "unprognostic (8.57e-2)" "unprognostic (3.73e-2)" "unprognostic (1.09e-2)" "unprognostic (2.28e-2)" "unprognostic (2.00e-1)" "unprognostic (6.86e-2)" "unprognostic (3.44e-1)" "unprognostic (1.02e-1)" "unprognostic (5.44e-2)" "unprognostic (4.98e-2)" 11.9 7.9 18.8 16.2 22.2 23.9 16.4 14.4 20.0 17.4 2.7 29.6 14.2 11.8 6.2 15.6 8.8 14.8 21.5 22.7 10.8 14.5 9.4 27.0 20.6 8.5 11.1 7.2 11.3 23.0 8.4 14.8 9.7 20.1 30.3 13.0 54.3 13.0 16.4 25.1 16.2 15.9 8.9 19.0 21.3 10.4 12.4 34.1 13.9 25.9 17.8 19.3 12.0 13.3 18.2 17.5 6.4 10.9 52.3 24.8 19.6 25.4 52.3 24.7 32.2 13.5 12.4 38.1 17.9 35.1 20.1 23.2 29.8 32.8 38.4 18.1 15.6 16.3 15.4 19.3 9.7 15.0 31.7 19.3 17.7 23.5 13.8 61.4 44.0 30.0 25.9 11.0 23.4 27.8 45.6 21.0 22.0 22.6 12.5 10.6 32.6 51.2 39.5 46.8 13.6 11.2 42.3 29.7 60.7 23.5 30.6 9.8 43.6 23.1 12.5 19.6 14.4 30.0 32.9 21.5 26.4 21.8 14.6 8.6 3.8 4.4 18.8 3.6 6.2 3.0 4.0 10.3 7.1 4.9 5.1 7.9 1.4 17.0 4.6 6.9 3.3 3.7 18.8 22.2 14.4 20.0 22.7 10.8 8.5 11.1 9.7 8.9 12.4 13.3 25.3 60.9 65.0 35.9 42.1 16.8 32.9 16.2 17.1 23.6 25.2 18.9 43.5 18.6 27.8 22.0 25.0 25.7 107.3 68.3 7.9 10.3 0.6 25.3 23.7 21.1 18.0 19.5 84.5 15.1 15.0 18.9 33.1 61.6 122.8 24.6 10.4 9.7 46.7 8.4 83.8 29.6 24.4 46.7 17.6 3.8 17.1 41.2 42.7 30.0 43.5 26.9 192.6 135.2 19.8 15.7 129.3 12.8 63.9 28.1 17.7 13.8 10.0 37.0 0.0 18.6 14.9 12.4 33.0 26.7 14.3 8.8 63.4 30.6 49.7 46.5 GOLGA2 "GM130, golgin-95" ENSG00000167110 "Golgin A2" Q08379 9 128255829-128275995 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015421, HPA021178, HPA021230, HPA021799" Enhanced Enhanced "Golgi apparatus" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "CAB015421: AB_831377, HPA021178: AB_1849837, HPA021230: AB_1849839, HPA021799: AB_1849841" "unprognostic (2.88e-2)" "unprognostic (2.73e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (3.70e-2)" "unprognostic (4.34e-2)" "unprognostic (1.84e-1)" "unprognostic (3.20e-1)" "unprognostic (2.83e-1)" "unprognostic (1.58e-1)" "unprognostic (3.50e-1)" "unprognostic (4.07e-1)" "unprognostic (2.21e-2)" "prognostic favorable (9.77e-5)" "unprognostic (3.92e-2)" "unprognostic (6.44e-2)" "unprognostic (4.84e-2)" "unprognostic (4.27e-2)" 51.8 44.2 31.5 31.3 31.8 33.4 49.6 30.4 31.5 73.5 44.1 48.2 28.9 57.0 59.7 75.0 49.9 42.2 63.9 30.9 36.2 42.3 50.3 47.3 24.5 34.0 36.3 57.4 65.3 77.4 122.4 56.9 36.7 54.4 44.5 31.4 65.1 54.9 57.2 73.4 38.0 58.1 28.7 33.4 51.7 35.8 33.0 23.3 53.3 51.1 32.1 48.6 66.3 31.8 49.1 48.1 52.8 54.9 130.4 148.3 46.3 93.6 129.2 79.4 71.1 60.7 44.7 23.1 34.4 154.3 84.4 94.4 30.3 47.4 74.2 34.1 28.9 25.5 114.0 48.3 85.2 38.2 71.4 95.4 74.0 79.1 81.9 124.9 64.3 55.1 83.8 58.6 77.6 99.8 33.0 33.9 16.2 92.0 86.2 32.9 58.1 40.0 63.4 42.5 29.3 34.9 62.5 52.1 43.2 53.3 117.0 32.2 86.3 102.9 51.8 66.9 50.8 40.7 51.1 29.7 89.8 20.0 65.6 32.4 6.6 12.2 6.2 5.3 3.8 6.0 4.1 3.4 2.7 7.3 4.4 6.1 30.2 7.4 8.2 13.2 3.6 2.9 31.5 31.8 30.4 31.5 30.9 36.2 34.0 36.3 36.7 28.7 33.0 31.8 33.9 44.8 66.8 20.9 27.0 31.7 27.7 45.1 41.5 68.0 53.8 34.8 88.1 45.8 57.8 42.3 41.7 37.9 32.6 69.6 43.0 47.6 41.5 62.9 82.2 35.5 46.1 18.7 15.1 60.8 35.6 67.1 59.7 94.3 65.9 33.6 44.6 72.3 28.3 25.2 20.4 90.9 40.7 24.9 23.1 7.7 68.3 34.2 24.9 10.3 19.5 33.4 28.8 15.6 15.5 57.7 45.1 64.7 55.6 43.7 42.6 35.4 73.2 51.7 13.1 59.6 43.3 99.5 51.1 71.4 45.5 102.3 28.1 29.5 42.6 44.2 GOLGA3 "GCP170, golgin-160, MEA-2" ENSG00000090615 "Golgin A3" Q08378 12 132768914-132829078 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 110.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039809, HPA040044" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus" Nucleoplasm "HPA039809: AB_10962348, HPA040044: AB_10981600" "unprognostic (1.93e-1)" "unprognostic (7.91e-2)" "unprognostic (6.80e-2)" "unprognostic (1.41e-1)" "unprognostic (2.56e-2)" "unprognostic (4.08e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (1.10e-1)" "unprognostic (7.69e-2)" "unprognostic (1.55e-2)" "prognostic favorable (3.87e-4)" "unprognostic (2.99e-1)" "prognostic unfavorable (6.47e-5)" "unprognostic (1.40e-2)" "unprognostic (1.45e-1)" "unprognostic (2.01e-2)" "unprognostic (1.20e-1)" 12.4 12.3 19.2 12.5 18.8 13.7 11.6 14.8 20.2 15.9 20.6 15.8 7.9 14.7 9.2 16.2 12.8 8.7 13.7 19.1 18.6 9.7 14.0 13.5 12.8 18.6 19.1 17.0 19.6 7.8 26.9 10.5 20.1 14.7 11.7 26.3 17.3 10.8 14.7 15.4 13.6 12.3 13.3 15.1 15.1 11.6 20.5 17.7 12.5 8.6 11.1 14.5 14.3 17.4 19.7 39.1 13.4 23.2 42.2 28.7 25.9 34.1 23.3 23.8 20.9 40.7 8.7 25.6 16.8 45.4 17.1 19.7 16.3 19.6 14.1 6.4 17.3 27.6 44.6 26.0 25.9 29.5 36.2 23.4 22.8 26.8 26.6 23.4 22.7 19.1 27.1 9.8 21.0 30.2 27.0 26.7 14.0 15.1 24.8 21.8 14.1 10.9 13.4 47.1 16.1 10.5 27.0 22.9 14.6 15.2 31.1 22.2 38.7 23.5 17.6 26.8 21.9 31.0 32.0 40.4 28.8 16.3 28.7 3.2 2.0 2.6 3.4 2.9 3.1 2.5 2.6 3.3 2.3 3.4 2.7 2.9 1.5 3.9 2.3 3.9 3.6 2.0 19.2 18.8 14.8 20.2 19.1 18.6 18.6 19.1 20.1 13.3 20.5 17.4 22.9 44.8 40.6 25.8 22.0 21.7 12.7 17.0 13.1 26.0 21.2 16.1 35.4 8.6 26.8 14.7 100.1 13.4 20.6 63.0 7.9 15.2 23.8 21.8 46.9 24.8 22.2 16.4 40.2 27.8 24.2 29.0 48.9 47.5 12.0 33.3 14.6 24.1 16.0 18.5 41.1 50.2 10.2 15.1 16.4 34.6 25.7 18.2 17.8 21.5 18.4 20.1 23.7 22.6 33.3 31.5 27.1 22.6 54.2 32.3 17.9 8.6 26.4 110.6 6.6 32.1 27.7 25.1 24.8 19.0 33.1 23.1 21.7 24.6 32.5 29.4 GOLIM4 "GIMPC, GOLPH4, GPP130, P138" ENSG00000173905 "Golgi integral membrane protein 4" O00461 3 168008689-168095924 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 370.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 10.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001677, HPA002315" Enhanced Enhanced "Golgi apparatus" NA NA 1000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA001677: AB_1079017, HPA002315: AB_1079018" "unprognostic (6.88e-2)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (6.27e-2)" "unprognostic (2.11e-1)" "unprognostic (4.76e-2)" "unprognostic (2.44e-1)" "unprognostic (5.17e-2)" "unprognostic (1.39e-1)" "unprognostic (6.46e-2)" "unprognostic (1.10e-1)" "unprognostic (6.31e-2)" "unprognostic (1.84e-3)" "unprognostic (9.03e-2)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-3)" 24.8 12.6 25.4 21.4 23.0 9.0 12.9 24.7 32.1 16.8 13.9 53.4 65.8 21.9 8.9 15.7 15.7 28.5 54.6 27.7 34.8 31.3 59.2 29.1 11.3 39.5 29.5 19.9 11.9 12.8 9.6 22.4 40.1 15.2 51.1 53.0 17.3 13.6 32.4 9.3 85.2 26.6 35.1 23.0 24.3 9.0 27.5 6.5 19.0 30.7 9.5 16.8 10.7 33.6 23.7 34.5 47.8 30.4 79.7 58.6 14.5 135.8 72.4 36.3 33.2 38.7 28.4 51.6 159.1 82.4 58.4 42.5 44.4 39.9 54.9 81.3 57.0 83.8 100.2 48.1 32.1 80.5 45.8 61.5 20.9 33.4 32.8 32.2 42.1 0.0 43.7 146.2 41.9 39.2 0.1 21.8 46.9 44.2 36.6 0.1 48.1 72.2 20.6 8.5 42.9 55.5 83.5 25.1 28.4 31.7 30.9 36.1 79.0 114.9 44.2 81.3 110.1 56.4 43.4 109.4 57.1 47.4 52.4 3.2 2.5 10.8 0.6 2.8 0.2 1.2 0.1 0.5 3.3 2.0 0.0 0.2 0.0 5.5 2.3 4.0 0.0 0.7 25.4 23.0 24.7 32.1 27.7 34.8 39.5 29.5 40.1 35.1 27.5 33.6 74.9 48.1 124.8 141.0 11.1 41.4 24.4 18.3 41.5 16.2 21.3 20.6 157.3 67.2 23.3 36.8 37.5 11.4 33.5 184.5 17.6 21.8 1.7 20.6 51.5 70.9 63.3 33.9 18.1 29.6 17.2 119.2 34.1 30.9 58.3 23.3 45.3 178.8 39.1 16.8 84.2 136.5 12.2 50.7 57.5 3.3 39.7 42.2 37.4 38.4 22.0 370.3 14.4 145.8 44.7 23.6 181.2 51.1 28.9 26.0 195.2 31.6 9.2 62.8 46.0 108.2 82.5 5.5 37.6 20.1 35.9 5.5 16.5 20.4 167.6 8.4 GPAT2 CT123 ENSG00000186281 "Glycerol-3-phosphate acyltransferase 2, mitochondrial" Q6NUI2 2 96021946-96039451 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Breast glandular cells: 84.5;Sertoli cells: 98.6;Smooth muscle cells: 30.3;Spermatocytes: 64.4;Spermatogonia: 45.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 8.2;BJ hTERT+ SV40 Large T+: 19.6;BJ hTERT+ SV40 Large T+ RasG12V: 11.6;OE19: 13.9;U-2 OS: 10.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036841 Uncertain Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" Mitochondria "HPA036841: AB_10601479" "unprognostic (1.42e-2)" "unprognostic (2.39e-2)" "unprognostic (6.69e-2)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (2.38e-3)" "unprognostic (4.99e-2)" "unprognostic (3.28e-2)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (5.96e-2)" "unprognostic (4.67e-2)" "unprognostic (7.43e-6)" "unprognostic (2.11e-1)" "unprognostic (7.68e-2)" "unprognostic (3.49e-1)" "unprognostic (3.65e-1)" 5.8 0.8 1.5 1.4 1.7 1.2 4.5 1.4 1.7 2.4 3.3 1.8 0.2 1.5 3.1 0.8 1.6 1.6 7.4 1.2 1.3 1.6 1.0 1.3 2.4 1.7 1.6 1.2 1.6 0.1 0.6 1.4 2.0 1.1 1.0 0.2 2.2 2.8 2.1 1.1 2.2 1.6 1.3 4.6 2.1 7.6 2.4 0.8 1.7 3.0 1.9 2.0 1.4 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 19.6 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.4 0.0 2.8 0.0 0.0 0.3 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 1.0 0.7 1.0 1.6 0.5 0.7 0.4 2.4 0.3 1.1 0.0 0.1 1.0 0.0 0.5 0.6 1.5 1.7 1.4 1.7 1.2 1.3 1.7 1.6 2.0 1.3 2.4 2.1 12.9 0.0 1.1 0.3 3.5 1.0 1.1 0.7 0.6 0.7 84.5 3.4 1.3 1.5 0.5 1.8 0.0 0.1 1.7 3.1 1.9 2.2 1.9 0.1 0.5 6.5 0.0 0.8 1.0 2.0 0.6 3.3 1.5 0.5 1.3 0.2 10.8 0.0 2.4 8.4 0.4 0.6 0.0 0.8 2.1 5.3 0.6 1.5 1.8 1.9 0.7 1.0 1.0 0.0 1.4 0.8 1.3 0.0 3.6 0.4 0.0 0.2 0.2 0.4 98.6 3.2 30.3 64.4 45.3 0.4 0.1 0.1 2.2 0.3 2.1 1.8 GPR176 Gm1012 ENSG00000166073 "G protein-coupled receptor 176" Q14439 15 39799008-39920266 "G-protein coupled receptors, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 22.3;Excitatory neurons: 32.0;Inhibitory neurons: 56.8;Oligodendrocyte precursor cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 276.1;fHDF/TERT166: 186.5;U-138 MG: 119.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039943, HPA039979" Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA039943: AB_10697711, HPA039979: AB_2676782" "unprognostic (4.02e-2)" "unprognostic (2.65e-1)" "unprognostic (1.99e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (1.04e-2)" "unprognostic (2.75e-2)" "unprognostic (1.38e-3)" "unprognostic (9.32e-2)" "unprognostic (3.23e-2)" "unprognostic (2.74e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (9.38e-7)" "prognostic unfavorable (6.84e-5)" "unprognostic (2.23e-1)" "unprognostic (1.95e-1)" "unprognostic (3.26e-2)" 13.2 6.1 10.0 4.1 10.6 0.3 6.6 11.2 10.5 6.8 1.1 3.9 2.0 5.6 2.0 1.7 4.4 7.0 4.2 10.1 10.4 3.9 1.9 7.5 6.3 9.7 8.8 1.8 1.6 1.9 5.0 2.4 12.3 7.1 2.3 6.3 2.9 3.6 1.7 3.5 3.4 4.6 6.0 4.1 2.2 7.2 8.8 2.1 5.0 1.1 5.8 6.4 5.3 5.9 52.3 2.6 3.2 0.6 36.9 64.6 0.0 108.3 276.1 64.3 99.5 3.7 8.3 0.7 8.7 186.5 37.1 1.6 7.7 8.4 100.7 1.7 11.2 7.7 7.7 0.1 41.1 0.0 0.4 50.7 1.0 56.7 47.6 65.7 24.6 2.4 1.0 1.1 91.8 2.1 0.1 0.0 3.2 0.4 9.3 2.7 32.3 0.3 1.6 0.6 12.0 47.8 27.9 0.0 4.4 0.7 9.0 0.5 31.8 119.5 33.9 7.2 40.7 1.1 3.6 0.1 24.9 0.0 47.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 10.6 11.2 10.5 10.1 10.4 9.7 8.8 12.3 6.0 8.8 5.9 3.0 0.0 0.0 8.5 0.9 1.8 0.2 0.8 0.0 1.1 0.4 0.6 0.9 1.5 0.1 0.0 0.0 0.0 0.3 0.1 0.0 9.3 22.3 0.1 3.1 1.8 0.0 0.0 32.0 3.9 0.0 3.4 0.0 0.2 0.0 0.1 0.7 0.1 0.1 1.7 56.8 0.0 0.0 0.0 1.8 13.5 1.2 0.7 1.8 3.7 0.0 14.9 0.0 40.7 1.4 12.0 0.0 1.2 3.1 3.0 0.0 1.2 0.0 1.1 13.1 3.8 15.2 2.9 3.8 0.5 1.0 0.0 0.4 0.8 0.0 0.1 GPRASP2 "FLJ37327, GASP2" ENSG00000158301 "G protein-coupled receptor associated sorting protein 2" Q96D09 X 102712176-102717733 "Disease related genes, Predicted intracellular proteins" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 19.6;Cardiomyocytes: 16.4;Horizontal cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017438 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Nucleoplasm "HPA017438: AB_1849504" "unprognostic (8.74e-3)" "unprognostic (1.99e-1)" "unprognostic (2.47e-2)" "unprognostic (5.14e-3)" "unprognostic (4.60e-2)" "unprognostic (5.06e-2)" "unprognostic (1.12e-1)" "unprognostic (1.89e-2)" "unprognostic (2.99e-1)" "unprognostic (1.06e-1)" "prognostic favorable (5.71e-4)" "unprognostic (1.42e-1)" "prognostic favorable (4.60e-6)" "unprognostic (1.19e-2)" "unprognostic (9.03e-2)" "unprognostic (8.05e-2)" "prognostic unfavorable (6.63e-5)" 5.1 15.0 19.1 2.1 18.9 0.4 7.8 10.6 22.3 13.6 6.7 7.5 1.7 17.7 9.0 4.2 10.7 5.1 14.5 18.6 31.4 10.2 6.8 5.0 1.8 13.8 15.0 30.1 9.3 14.9 20.0 3.7 15.8 12.5 3.1 12.7 9.2 11.8 7.5 5.8 3.2 10.3 12.8 4.2 4.0 4.7 24.8 4.5 15.2 6.5 1.7 6.4 6.5 13.4 0.6 6.8 17.8 13.8 5.5 6.5 1.3 10.3 9.3 8.7 16.9 2.3 3.1 0.0 3.5 10.8 4.3 2.4 21.5 5.6 11.0 0.0 8.3 0.9 2.0 0.5 4.0 1.7 1.2 6.9 5.8 9.7 0.4 10.1 6.2 1.7 2.7 0.7 10.6 3.2 4.9 0.7 8.9 2.2 9.3 6.4 2.9 0.0 5.4 2.5 3.9 12.2 10.4 2.0 1.5 5.4 5.7 3.6 5.6 6.1 12.9 12.5 9.9 0.3 0.4 0.0 8.2 1.1 3.5 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.3 0.4 0.2 0.1 1.4 0.6 0.0 0.8 0.0 0.5 0.5 0.4 19.1 18.9 10.6 22.3 18.6 31.4 13.8 15.0 15.8 12.8 24.8 13.4 4.3 0.0 1.5 0.0 0.5 2.3 5.1 2.1 4.0 19.6 3.5 4.1 16.4 7.2 3.6 5.5 2.1 6.2 0.3 0.6 9.8 1.6 0.5 0.7 4.1 4.3 3.0 0.0 0.0 0.9 0.5 6.6 0.0 0.6 0.0 13.2 8.2 7.3 0.9 16.8 0.0 1.4 2.0 0.6 0.8 1.1 12.2 0.6 0.0 0.0 0.5 12.2 0.0 0.0 0.0 1.1 1.8 12.4 0.0 3.2 0.3 10.8 0.8 6.8 6.6 8.9 4.9 13.4 9.1 2.4 3.0 2.2 0.7 8.0 1.1 1.5 GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 62.7;Extravillous trophoblasts: 218.9;Fibroblasts: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 254.4;fHDF/TERT166: 246.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: AB_2675269" "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (5.13e-9)" "prognostic unfavorable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" 13.3 6.1 1.2 12.5 1.2 0.1 12.6 1.2 1.6 37.1 6.9 7.3 2.9 21.1 21.9 6.2 14.3 17.0 11.2 1.0 1.7 6.5 2.2 6.9 3.8 1.5 1.1 27.3 4.6 9.3 2.4 39.7 1.4 10.2 8.4 1.3 7.2 15.8 1.5 5.0 4.1 27.2 1.5 4.0 5.6 5.6 1.2 1.3 22.3 6.3 3.0 17.8 9.8 3.6 37.2 39.0 75.3 77.0 180.7 223.9 36.6 179.8 254.4 97.0 192.7 3.2 82.1 0.0 199.0 246.4 86.5 28.2 46.0 51.5 131.5 0.5 17.3 2.1 49.1 6.9 64.4 0.0 0.0 157.5 60.8 68.3 35.5 126.5 122.7 0.0 1.1 0.1 137.4 14.4 0.0 0.0 32.6 1.0 42.8 0.1 40.2 0.0 65.9 1.3 0.1 1.4 56.6 4.6 68.0 80.8 56.6 3.4 102.7 63.6 65.6 84.5 102.3 0.1 0.5 0.5 103.0 0.1 118.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 1.6 1.0 1.7 1.5 1.1 1.4 1.5 1.2 3.6 10.9 0.0 1.1 0.3 0.3 7.1 6.0 38.3 9.1 0.2 8.9 6.1 4.3 0.0 33.3 25.8 0.0 49.5 0.2 0.5 5.9 13.7 0.4 6.5 62.7 18.6 0.0 0.0 0.1 38.8 218.9 76.6 2.6 4.9 4.5 30.9 19.2 0.2 10.2 0.0 0.1 4.7 4.1 0.0 6.9 0.6 51.3 1.1 24.9 5.6 1.1 7.9 0.0 0.0 0.1 15.8 0.3 39.9 1.4 2.6 0.1 0.5 36.5 0.3 13.1 20.1 38.2 0.1 0.4 3.1 6.1 13.3 1.8 29.9 0.9 2.4 GRAMD2B "FLJ21313, GRAMD3, NS3TP2" ENSG00000155324 "GRAM domain containing 2B" Q96HH9 5 126360132-126496494 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 73.2;Club cells: 45.8;Endometrial ciliated cells: 51.8;Endometrial stromal cells: 49.0;Extravillous trophoblasts: 46.5;Glandular and luminal cells: 153.2;Respiratory ciliated cells: 48.8;Syncytiotrophoblasts: 58.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.9;MAIT T-cell: 2.8;memory CD4 T-cell: 1.6;memory CD8 T-cell: 2.3;myeloid DC: 1.7;naive CD4 T-cell: 3.0;naive CD8 T-cell: 1.8;NK-cell: 1.1;plasmacytoid DC: 4.3;T-reg: 2.4" "Group enriched" "Detected in many" 6 "dendritic cells: 4.3;NK-cells: 1.1;T-cells: 3.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 114.1;CAPAN-2: 73.6;fHDF/TERT166: 75.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009678, HPA010095" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Cytosol "Nucleoplasm, Golgi apparatus" "HPA009678: AB_2112580, HPA010095: AB_1849952" "unprognostic (2.34e-1)" "unprognostic (4.01e-1)" "unprognostic (4.63e-2)" "unprognostic (3.42e-2)" "unprognostic (6.82e-2)" "unprognostic (1.95e-2)" "unprognostic (6.76e-2)" "unprognostic (3.84e-2)" "unprognostic (9.90e-2)" "unprognostic (7.42e-2)" "unprognostic (2.09e-2)" "unprognostic (3.78e-1)" "unprognostic (2.20e-3)" "unprognostic (3.56e-3)" "unprognostic (2.39e-1)" "unprognostic (9.24e-2)" "unprognostic (1.12e-2)" 12.8 16.0 56.5 6.9 57.1 1.6 38.7 54.1 55.1 32.2 47.7 28.6 29.6 29.4 15.5 8.9 34.3 10.9 11.7 49.4 54.6 32.9 24.4 11.3 7.4 61.3 64.7 30.3 8.9 8.7 10.0 24.7 55.2 16.9 29.8 6.6 23.1 23.7 3.8 27.3 36.0 22.1 64.9 6.1 16.4 4.1 54.0 13.2 40.4 5.6 11.2 13.8 16.3 60.5 66.1 3.7 3.0 14.6 62.4 21.5 19.4 71.2 114.1 28.7 37.2 2.6 73.6 0.0 26.4 75.4 0.7 17.5 0.9 27.6 30.9 6.1 4.8 3.1 8.2 3.9 14.2 0.0 2.3 34.6 10.4 29.2 9.4 36.4 0.2 0.0 0.0 0.0 50.7 6.7 0.0 0.9 3.1 13.7 4.6 1.3 17.6 14.3 38.8 69.1 1.1 0.1 11.9 6.0 21.2 12.8 22.9 4.2 6.6 6.6 2.1 11.6 12.7 3.9 3.5 0.1 1.4 0.0 19.2 0.2 0.4 0.0 2.9 0.4 2.8 0.5 1.6 2.3 1.7 0.2 3.0 1.8 0.3 1.1 0.3 4.3 2.4 1.2 56.5 57.1 54.1 55.1 49.4 54.6 61.3 64.7 55.2 64.9 54.0 60.5 10.2 16.0 17.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 25.5 73.2 0.0 0.0 45.8 40.5 0.0 32.3 10.0 0.0 23.5 14.1 0.0 51.8 49.0 3.2 0.0 0.0 0.0 8.7 46.5 8.7 0.0 153.2 3.8 4.9 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 2.8 0.0 0.0 18.3 48.8 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 58.6 4.7 2.8 0.0 0.0 GREM1 "CKTSF1B1, CRAC1, DAND2, DRM, gremlin, HMPS" ENSG00000166923 "Gremlin 1, DAN family BMP antagonist" O60565 15 32718004-32745106 "Disease related genes, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 113.0;smooth muscle: 68.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 66.2;Granulosa cells: 121.1;Oligodendrocytes: 40.5;Skeletal myocytes: 181.4" "Cancer enhanced" "Detected in many" "stomach cancer: 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 294.7;BJ hTERT+: 468.5;BJ hTERT+ SV40 Large T+ RasG12V: 286.8;fHDF/TERT166: 957.0;hTEC/SVTERT24-B: 227.8" "Group enriched" "Detected in many" 5 "hippocampal formation: 3.2;olfactory bulb: 10.9" "Low region specificity" "Detected in many" HPA007526 Uncertain "Secreted to blood" NA NA 242000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA007526: AB_1849971" "unprognostic (4.74e-2)" "unprognostic (2.78e-1)" "unprognostic (4.63e-2)" "unprognostic (6.80e-2)" "unprognostic (3.58e-1)" "unprognostic (1.72e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (5.33e-2)" "unprognostic (2.32e-1)" "unprognostic (7.20e-3)" "unprognostic (2.79e-1)" "unprognostic (2.13e-11)" "unprognostic (1.77e-2)" "unprognostic (6.60e-2)" "unprognostic (3.29e-2)" "unprognostic (1.16e-3)" 32.7 0.5 1.4 6.5 3.6 0.2 5.5 1.1 2.4 44.7 0.0 36.1 2.6 9.6 0.0 13.6 1.1 113.0 1.3 1.5 1.3 1.2 1.1 2.2 1.1 3.1 3.0 0.3 2.2 0.0 0.2 0.3 1.8 8.2 26.7 0.1 0.6 3.8 0.6 7.6 52.3 68.2 1.1 0.8 36.8 0.5 3.8 0.0 2.3 0.0 1.7 21.7 50.4 6.1 0.0 3.5 0.0 0.0 11.1 12.5 0.0 294.7 468.5 112.5 286.8 0.3 0.0 0.0 0.0 957.0 0.0 0.0 0.0 0.0 109.7 0.0 0.1 0.0 0.1 0.0 3.3 0.0 0.0 3.1 0.0 227.8 0.1 70.6 0.0 0.0 0.0 0.0 143.4 0.1 0.0 0.0 1.2 0.0 0.9 0.0 20.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.0 57.7 0.0 0.1 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 3.6 1.1 2.4 1.5 1.3 3.1 3.0 1.8 1.1 3.8 6.1 0.7 0.0 0.0 0.3 0.4 6.6 6.5 0.0 0.6 2.1 1.7 0.9 3.4 0.0 0.0 66.2 2.1 0.2 0.7 0.4 0.0 0.4 0.2 0.6 2.3 1.9 0.0 0.0 2.5 0.0 0.1 17.7 0.0 0.7 0.0 121.1 0.7 1.2 1.0 1.7 0.5 0.6 0.0 0.3 12.8 0.0 0.0 2.3 3.6 0.0 2.7 0.3 0.0 1.5 40.5 0.3 0.0 0.4 0.2 9.9 0.1 0.3 0.0 1.3 0.0 181.4 16.1 0.1 1.4 0.3 4.5 0.3 2.1 0.1 0.1 6.5 GREM2 "CKTSF1B2, DAND3, FLJ21195, Prdc" ENSG00000180875 "Gremlin 2, DAN family BMP antagonist" Q9H772 1 240489573-240612155 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Heparin-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 31.4;liver: 26.3" "Cell type enriched" "Detected in many" 9 "Syncytiotrophoblasts: 298.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 32.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB009920 Approved "Secreted to blood" NA NA 12000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB009920: AB_2279266" "unprognostic (2.01e-1)" "unprognostic (2.49e-1)" "unprognostic (7.41e-2)" "unprognostic (7.58e-3)" "unprognostic (2.82e-3)" "unprognostic (1.34e-1)" "unprognostic (8.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.31e-2)" "unprognostic (6.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.97e-2)" "unprognostic (3.07e-8)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.38e-2)" 0.8 1.7 2.1 9.7 2.9 0.1 3.4 0.1 6.1 0.9 0.0 17.1 10.8 9.6 2.2 17.1 1.4 31.4 0.0 1.3 1.8 2.3 26.3 1.2 0.2 2.1 1.7 6.6 0.2 22.9 2.1 4.0 1.9 2.6 20.1 5.8 4.2 1.8 7.3 3.6 14.9 6.4 1.3 3.2 9.3 0.3 2.8 0.3 0.5 0.7 0.2 3.8 0.5 2.0 0.0 0.0 0.1 0.0 1.9 2.4 0.0 6.1 6.5 0.0 0.0 0.0 0.0 0.0 0.0 32.3 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 2.2 0.0 2.8 1.3 0.0 0.0 3.9 0.5 0.8 0.4 1.0 0.0 0.0 3.3 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 2.9 0.1 6.1 1.3 1.8 2.1 1.7 1.9 1.3 2.8 2.0 0.2 0.0 0.0 0.3 0.2 4.7 0.0 0.0 0.6 20.8 14.0 0.1 0.6 0.0 0.0 0.0 12.5 7.4 0.6 0.6 0.0 0.0 0.0 2.3 1.2 0.6 1.2 0.0 28.6 0.0 1.7 17.4 0.0 13.7 0.0 0.1 0.7 20.4 1.5 0.0 30.5 0.1 0.0 0.3 6.2 0.2 0.0 0.2 1.8 3.7 0.0 0.4 1.0 1.5 1.2 0.1 0.1 4.5 0.1 0.6 0.0 0.0 0.7 6.7 0.0 0.2 1.4 2.4 2.7 0.6 3.7 298.0 1.6 2.3 0.6 0.1 GRIA3 "GluA3, GLUR3, GLURC, MRX94" ENSG00000125675 "Glutamate ionotropic receptor AMPA type subunit 3" P42263 X 123184153-123490915 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.6;retina: 17.8" "Group enriched" "Detected in some" 5 "Excitatory neurons: 468.4;Horizontal cells: 198.5;Inhibitory neurons: 396.3;Oligodendrocyte precursor cells: 385.0" "Cancer enriched" "Detected in some" 11 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 23.8;BJ hTERT+: 34.5;fHDF/TERT166: 45.9;U-2197: 15.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058659, HPA073344" Enhanced "Intracellular and membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA058659: AB_2683791, HPA073344: " "unprognostic (2.14e-2)" "unprognostic (6.00e-2)" "unprognostic (2.02e-2)" "unprognostic (2.94e-3)" "unprognostic (5.09e-2)" "unprognostic (4.29e-4)" "unprognostic (2.42e-1)" "unprognostic (6.74e-2)" "unprognostic (1.44e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-3)" "unprognostic (1.31e-1)" "unprognostic (3.78e-3)" "unprognostic (8.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" 0.8 10.3 20.0 0.3 25.3 0.1 1.4 1.3 31.6 6.7 0.0 0.7 0.3 2.1 3.6 0.4 1.5 1.2 2.0 29.0 4.0 2.5 7.7 0.3 0.5 1.9 3.4 4.1 1.7 0.0 1.0 0.4 1.4 1.7 0.8 17.8 0.2 1.9 0.2 0.5 0.5 1.9 4.5 0.1 2.0 0.7 6.4 0.2 0.2 0.1 0.8 0.6 2.8 20.9 0.0 0.0 0.0 0.0 2.2 0.4 0.0 23.8 34.5 0.4 0.9 0.0 0.0 0.0 0.0 45.9 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 6.6 0.0 15.1 0.2 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 25.3 1.3 31.6 29.0 4.0 1.9 3.4 1.4 4.5 6.4 20.9 0.1 0.0 0.0 27.4 0.0 0.3 0.0 0.8 0.6 13.6 0.2 0.0 1.6 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.1 0.3 8.7 0.3 0.0 0.0 468.4 0.2 0.1 6.4 1.1 0.2 0.0 0.1 0.4 6.1 0.1 198.5 396.3 0.0 0.0 0.0 1.5 0.3 9.3 0.2 1.8 14.0 0.0 1.9 0.0 385.0 67.6 0.3 0.0 4.1 0.0 0.4 0.0 6.2 0.1 3.8 0.0 0.2 4.5 0.0 0.1 0.0 1.0 0.1 0.1 0.7 0.0 0.0 GRIK2 "GluK2, GLUR6, MRT6" ENSG00000164418 "Glutamate ionotropic receptor kainate type subunit 2" Q13002 6 101181257-102070083 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "brain: 93.3" "Group enriched" "Detected in some" 26 "Excitatory neurons: 724.6;Inhibitory neurons: 2376.0;Oligodendrocyte precursor cells: 1234.0" "Cancer enriched" "Detected in some" 5 "glioma: 3.9" "Region enhanced" "Detected in all" "cerebellum: 93.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 16.4;BJ hTERT+: 26.6;fHDF/TERT166: 20.8;HAP1: 10.2;SiHa: 11.1;WM-115: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014395, HPA014623, CAB022463" Approved "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022463: , HPA014395: AB_1850303, HPA014623: AB_1850305" "unprognostic (1.43e-3)" "unprognostic (1.26e-2)" "unprognostic (3.99e-2)" "unprognostic (3.20e-1)" "unprognostic (1.92e-1)" "unprognostic (3.48e-2)" "unprognostic (2.57e-1)" "unprognostic (4.32e-2)" "unprognostic (8.46e-2)" "unprognostic (9.19e-2)" "unprognostic (4.01e-2)" "unprognostic (1.36e-1)" "unprognostic (1.34e-5)" "unprognostic (1.94e-3)" "unprognostic (7.78e-2)" "unprognostic (1.09e-2)" "unprognostic (8.68e-4)" 0.2 1.8 18.7 0.4 20.3 0.3 0.2 93.3 25.2 1.4 0.0 0.5 0.6 0.4 1.1 0.4 0.3 0.5 4.5 20.7 28.4 0.8 0.1 0.1 0.1 1.0 6.8 0.4 2.6 0.0 1.6 2.4 7.9 0.9 0.4 4.2 0.7 1.2 0.9 1.6 0.6 0.3 1.6 0.4 0.3 0.7 19.8 0.0 3.4 0.1 0.0 0.5 0.4 7.6 0.1 0.1 3.1 0.2 3.6 0.1 0.0 16.4 26.6 0.8 0.5 0.0 0.3 0.1 0.0 20.8 0.0 5.1 10.2 0.0 0.3 0.0 0.0 1.7 8.5 0.0 0.9 0.0 0.2 0.3 0.0 0.0 1.0 2.3 0.0 0.0 0.0 0.4 6.2 0.0 0.0 0.2 2.7 0.0 0.2 0.1 0.4 0.1 0.7 0.0 3.3 7.0 11.1 0.0 0.5 0.5 0.0 0.8 0.0 2.1 0.5 0.1 1.3 0.1 0.0 0.1 1.5 0.0 24.6 0.5 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.0 0.0 18.7 20.3 93.3 25.2 20.7 28.4 1.0 6.8 7.9 1.6 19.8 7.6 0.2 0.0 0.5 54.9 0.0 0.6 1.0 0.1 0.6 11.4 0.1 0.0 5.9 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 3.8 3.4 1.9 0.4 1.8 0.0 724.6 0.6 0.0 1.8 0.0 0.5 0.0 13.0 0.0 0.0 0.1 0.0 2376.0 0.0 0.0 0.0 0.0 7.7 0.3 0.1 1.8 38.4 0.0 0.5 0.0 1234.0 40.5 0.1 1.1 0.4 0.0 0.8 0.1 0.0 2.2 1.1 0.0 0.7 4.6 0.0 0.5 0.1 0.6 0.0 0.0 4.3 0.1 0.9 GRIN2A "GluN2A, NMDAR2A" ENSG00000183454 "Glutamate ionotropic receptor NMDA type subunit 2A" Q12879 16 9753404-10182928 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 31.7" "Group enriched" "Detected in some" 13 "Excitatory neurons: 839.8;Inhibitory neurons: 904.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 31.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;fHDF/TERT166: 4.4;hTERT-RPE1: 1.4;RPMI-8226: 1.8;U-138 MG: 4.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022725 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022725: " "unprognostic (6.43e-2)" "unprognostic (2.47e-1)" "unprognostic (5.97e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-2)" "unprognostic (1.59e-2)" "unprognostic (1.62e-1)" "unprognostic (2.10e-1)" "unprognostic (2.08e-1)" "unprognostic (5.39e-2)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (3.75e-3)" "unprognostic (4.79e-3)" "unprognostic (2.05e-1)" "unprognostic (3.92e-3)" "unprognostic (3.33e-2)" 0.3 0.3 4.7 0.0 8.4 0.0 0.1 0.0 31.7 0.3 0.0 0.2 0.3 0.3 2.5 1.1 2.1 0.1 3.0 20.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.2 2.2 0.2 0.3 0.0 0.5 0.2 0.4 0.0 0.0 0.4 2.1 0.1 0.6 0.2 0.2 0.2 0.1 0.4 10.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.3 1.1 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 8.4 0.0 31.7 20.0 0.0 0.0 0.0 0.0 0.0 0.1 10.3 0.2 0.0 0.0 16.0 0.0 1.9 2.2 0.5 3.4 10.3 0.3 0.0 18.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 2.1 17.2 0.3 0.1 0.5 0.0 0.0 839.8 0.2 0.0 2.7 0.0 0.7 0.0 3.3 0.0 0.3 0.1 1.7 904.7 0.0 0.0 0.3 0.4 15.1 0.9 0.1 0.0 15.9 0.0 15.6 0.0 27.6 65.8 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 13.9 0.0 0.0 5.4 8.2 10.0 0.2 0.4 0.0 0.0 0.0 0.1 0.3 GRP ENSG00000134443 "Gastrin releasing peptide" P07492 18 59220158-59230774 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;stomach 1: 12.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 24.4;Early spermatids: 15.5;Ionocytes: 6.1;Late spermatids: 12.2;Sertoli cells: 6.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.6" "Region enriched" "Detected in all" 4 "midbrain: 26.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BJ hTERT+: 5.1;fHDF/TERT166: 6.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 24.9" "Secreted in other tissues" NA NA 340000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.91e-2)" "unprognostic (1.85e-1)" "unprognostic (2.30e-3)" "unprognostic (3.21e-2)" "unprognostic (7.86e-3)" "unprognostic (3.01e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-1)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (1.79e-1)" "unprognostic (5.86e-4)" "unprognostic (2.65e-4)" "unprognostic (9.94e-2)" "unprognostic (6.99e-2)" "unprognostic (5.16e-2)" 0.3 0.2 3.2 0.2 2.6 0.0 2.6 1.3 5.0 0.1 2.8 2.1 0.1 0.3 0.3 0.0 0.0 0.3 0.0 6.1 6.0 0.4 0.0 9.0 0.0 3.0 26.1 0.0 1.2 7.0 3.9 0.0 2.4 2.7 0.1 0.5 0.0 0.1 0.0 0.4 0.7 1.2 2.6 0.3 12.3 2.4 3.5 0.1 6.1 0.0 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.2 0.0 0.0 0.0 0.4 0.0 6.6 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.6 1.3 5.0 6.1 6.0 3.0 26.1 2.4 2.6 3.5 1.6 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.2 0.0 0.0 0.4 24.4 0.1 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 2.0 0.5 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.3 12.2 0.3 0.1 0.0 4.7 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.1 6.6 0.0 0.2 1.2 0.9 0.0 0.0 0.0 0.3 0.0 0.0 4.2 GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109711780-109775428 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 929.9" "Group enriched" "Detected in many" 4 "Fibroblasts: 59.0;Leydig cells: 143.5;Muller glia cells: 213.3;Peritubular cells: 127.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.9" "Group enriched" "Detected in some" 5 "fHDF/TERT166: 21.6;HHSteC: 10.3;HSkMC: 10.9" "HPA055972, HPA055973" Approved Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (1.46e-2)" "unprognostic (8.64e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (5.34e-3)" "unprognostic (8.09e-2)" "unprognostic (9.64e-4)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (3.74e-2)" "unprognostic (4.39e-2)" "unprognostic (3.03e-3)" "unprognostic (1.40e-1)" 21.7 6.4 60.3 4.6 65.3 0.5 929.9 60.4 71.1 72.5 62.9 13.9 2.3 35.1 32.9 11.6 62.0 25.8 17.0 61.4 54.5 5.5 3.9 18.0 5.0 57.2 55.4 213.9 4.7 0.2 9.4 0.8 56.7 27.9 7.8 12.4 7.9 32.6 3.9 12.2 10.3 26.5 60.1 7.7 13.2 11.4 53.5 6.4 9.1 14.0 6.5 27.9 47.6 58.6 0.0 0.0 0.0 0.0 1.7 1.6 0.4 1.3 0.0 0.3 0.2 0.0 0.0 0.1 0.0 21.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.8 0.0 0.0 10.3 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.6 0.0 3.9 0.9 0.7 60.3 65.3 60.4 71.1 61.4 54.5 57.2 55.4 56.7 60.1 53.5 58.6 2.5 0.0 0.5 32.3 0.0 6.6 0.9 0.2 0.0 2.0 0.5 0.8 0.9 1.5 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.0 9.0 0.3 12.3 2.2 0.0 2.1 0.1 0.0 0.1 59.0 1.1 0.3 0.0 0.6 5.7 0.0 0.3 0.0 0.5 0.1 0.0 0.6 9.3 15.1 143.5 0.6 10.6 1.9 0.0 213.3 0.0 2.0 0.3 0.0 0.0 127.2 0.1 0.1 0.1 0.0 0.0 6.8 26.3 2.3 9.4 2.0 1.8 1.0 6.5 0.0 2.8 2.4 0.1 0.6 GUCD1 "C22orf13, LLN4, MGC1842" ENSG00000138867 "Guanylyl cyclase domain containing 1" Q96NT3 22 24540423-24555935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 161.3;Proximal enterocytes: 149.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022786 Approved Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA022786: AB_1845711" "unprognostic (1.58e-1)" "prognostic favorable (6.84e-4)" "unprognostic (2.83e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.51e-2)" "unprognostic (1.61e-1)" "unprognostic (3.96e-2)" "unprognostic (1.89e-1)" "prognostic favorable (7.26e-4)" "unprognostic (1.28e-1)" "unprognostic (3.55e-2)" "unprognostic (1.76e-2)" "unprognostic (4.36e-2)" "unprognostic (8.63e-2)" "unprognostic (1.59e-1)" "unprognostic (3.01e-2)" 36.9 27.5 19.3 25.3 22.0 89.9 29.2 20.5 18.9 19.6 17.7 37.5 67.5 19.1 16.7 25.2 21.1 25.4 62.0 17.0 19.8 43.0 93.9 34.3 34.6 23.4 23.4 19.4 37.1 24.1 12.3 21.6 21.3 31.0 36.2 10.9 25.0 20.2 96.4 27.6 59.6 23.1 22.1 30.4 37.1 18.8 23.1 27.9 16.6 117.6 36.9 26.8 19.8 22.2 40.8 37.1 30.9 38.5 62.5 58.4 25.7 38.7 59.5 63.3 61.0 56.9 30.2 72.1 26.0 50.9 39.3 51.2 35.2 43.3 33.6 74.2 45.4 31.3 36.1 51.3 50.6 83.2 63.2 59.6 33.9 64.0 29.0 38.7 67.5 35.9 32.3 75.6 48.4 47.2 49.2 34.1 31.0 95.3 30.6 57.2 52.0 73.1 49.8 44.9 33.8 33.2 47.2 60.6 33.3 23.6 49.6 56.7 48.7 143.4 59.8 44.5 34.6 70.1 53.8 50.8 57.9 45.3 49.9 20.2 14.9 52.5 7.4 14.8 8.5 37.0 7.1 7.7 13.7 42.6 6.7 7.6 15.2 7.5 14.5 9.7 7.6 13.8 19.3 22.0 20.5 18.9 17.0 19.8 23.4 23.4 21.3 22.1 23.1 22.2 20.5 16.0 33.9 6.8 41.5 12.4 11.8 13.9 21.1 5.3 25.9 18.3 51.2 78.6 13.3 5.5 6.2 18.6 21.2 99.7 52.8 27.1 15.8 13.4 13.6 16.4 19.8 86.1 2.3 66.0 20.1 17.5 35.7 17.9 15.2 19.5 18.5 161.3 27.1 3.3 3.0 52.3 16.2 23.5 12.0 8.6 19.0 21.0 17.8 2.8 28.6 18.2 18.6 5.5 7.5 48.1 72.4 16.1 17.5 32.1 149.6 84.9 9.7 13.2 26.3 12.4 16.7 24.3 32.0 18.7 11.1 16.3 14.6 28.9 36.7 18.9 GYS1 "GSY, GYS" ENSG00000104812 "Glycogen synthase 1" P13807 19 48968130-48993310 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 118.5;skeletal muscle: 319.4;tongue: 201.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007793, HPA041598" Enhanced Approved Microtubules,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Microtubules, Cytosol" "CAB007793: AB_562291, HPA041598: AB_2677571" "unprognostic (3.37e-1)" "unprognostic (3.07e-1)" "unprognostic (1.02e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (6.83e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (3.30e-2)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.46e-4)" "unprognostic (4.04e-2)" "unprognostic (6.76e-2)" "unprognostic (5.87e-3)" "unprognostic (3.81e-2)" 32.4 26.3 17.9 16.2 18.8 46.0 23.7 26.4 23.3 17.1 22.2 21.7 15.3 18.8 8.9 38.2 18.7 10.1 118.5 19.7 17.6 21.8 14.9 16.0 15.5 22.2 20.9 19.7 13.6 15.7 15.5 11.3 19.6 27.4 14.7 19.2 22.2 15.5 319.4 20.7 19.9 16.7 16.4 18.5 23.2 6.1 20.2 14.7 15.9 201.6 14.4 24.3 23.2 18.3 67.3 26.3 19.0 26.3 43.2 16.9 37.6 45.5 31.7 46.8 54.3 25.8 21.3 28.0 27.0 44.7 12.4 46.6 32.0 57.7 40.6 17.4 46.5 23.1 33.3 23.1 24.3 25.4 15.9 41.8 27.2 30.2 25.4 40.5 39.8 28.8 16.4 36.1 59.4 25.4 31.8 21.9 10.2 29.0 29.8 26.6 33.2 27.5 46.7 70.6 11.8 16.4 40.5 52.1 10.4 25.2 27.7 26.1 31.0 57.1 22.0 26.1 50.5 29.8 33.1 13.5 58.3 22.2 13.1 7.7 9.4 6.6 7.0 5.3 8.6 5.2 6.0 6.5 13.4 3.9 4.7 4.4 3.7 10.6 8.0 7.2 8.6 7.1 17.9 18.8 26.4 23.3 19.7 17.6 22.2 20.9 19.6 16.4 20.2 18.3 3.5 0.0 14.2 21.9 5.9 5.1 3.7 11.7 11.4 4.2 7.3 5.5 67.9 2.8 5.8 0.0 16.7 7.6 6.8 13.2 0.0 8.1 0.3 6.9 8.9 7.1 7.2 4.8 14.7 6.9 31.7 5.0 12.8 11.9 4.5 6.7 9.7 5.2 8.3 0.0 16.6 9.2 4.1 7.0 5.7 0.7 5.3 7.2 7.2 4.7 9.8 3.3 10.3 8.5 6.9 11.8 8.2 5.7 9.7 5.4 9.2 6.0 6.2 11.7 0.0 5.0 7.3 1.3 2.9 15.3 4.1 4.0 5.2 3.8 11.7 3.3 HAS2 ENSG00000170961 "Hyaluronan synthase 2" Q92819 8 121612116-121641440 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 22.7;urinary bladder: 20.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 54.1;Fibroblasts: 62.1;Langerhans cells: 28.9;Melanocytes: 30.2;Smooth muscle cells: 30.7;Urothelial cells: 89.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HBF TERT88: 157.8;hTEC/SVTERT24-B: 153.8;LHCN-M2: 206.5;U-138 MG: 396.9;U-251 MG: 123.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052060 Approved "Nuclear speckles" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA052060: AB_2681712" "unprognostic (7.01e-2)" "unprognostic (1.34e-2)" "unprognostic (4.07e-2)" "unprognostic (4.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.91e-2)" "unprognostic (5.33e-2)" "unprognostic (2.57e-3)" "unprognostic (3.44e-2)" "unprognostic (1.34e-1)" "unprognostic (8.19e-3)" "unprognostic (1.24e-1)" "unprognostic (1.66e-7)" "unprognostic (1.47e-3)" "unprognostic (3.67e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-3)" 22.7 0.3 0.6 9.0 0.5 0.1 5.3 0.6 0.5 0.7 0.1 4.1 2.8 0.8 1.2 1.6 1.7 7.8 4.0 0.5 1.5 1.1 2.9 3.7 1.6 1.6 2.1 0.2 0.9 0.2 0.3 2.3 1.3 1.1 5.6 0.0 1.0 0.2 0.5 2.3 5.2 3.9 1.1 0.1 2.0 1.8 1.3 0.8 0.7 0.9 0.9 20.5 0.6 0.9 0.3 2.8 0.0 0.4 4.7 11.8 0.0 23.5 17.3 29.9 51.2 0.2 0.4 0.1 0.0 20.8 0.0 4.2 0.0 0.0 157.8 0.1 0.6 0.0 0.6 0.0 19.9 0.0 0.0 31.0 0.0 153.8 14.1 0.7 0.0 0.0 0.0 0.0 206.5 0.3 0.0 0.0 0.4 0.0 3.4 0.0 26.6 0.0 0.0 2.0 0.0 0.4 10.0 0.0 5.6 9.0 0.2 0.3 0.0 396.9 1.4 37.7 123.7 0.0 0.0 0.0 8.5 0.1 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.6 0.5 0.5 1.5 1.6 2.1 1.3 1.1 1.3 0.9 2.2 0.0 0.0 0.0 0.0 16.3 54.1 1.8 0.6 0.0 0.1 0.4 1.2 0.0 0.2 3.7 0.0 0.2 0.2 1.6 0.0 0.9 19.0 0.1 3.5 7.2 1.2 0.0 0.1 0.0 0.0 62.1 1.1 0.1 13.4 0.0 0.7 0.0 0.3 0.0 0.2 2.3 0.0 0.0 28.9 3.4 1.8 0.7 30.2 0.0 0.0 0.0 0.0 16.1 0.2 1.6 1.9 0.0 0.0 11.0 0.0 0.1 0.0 0.0 0.0 6.9 30.7 0.3 0.1 0.6 11.9 0.1 1.5 0.0 3.9 89.3 HDAC5 "FLJ90614, KIAA0600, NY-CO-9" ENSG00000108840 "Histone deacetylase 5" Q9UQL6 17 44076746-44123702 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 118.9;Syncytiotrophoblasts: 218.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019400, HPA030991" Approved Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear speckles" "Golgi apparatus, Cytosol" "CAB019400: AB_2116626, HPA030991: AB_10795286" "unprognostic (1.30e-2)" "prognostic favorable (6.14e-4)" "unprognostic (6.65e-2)" "unprognostic (8.06e-2)" "unprognostic (3.49e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (8.80e-3)" "unprognostic (3.80e-2)" "unprognostic (2.37e-2)" "unprognostic (4.91e-3)" "unprognostic (4.30e-1)" "prognostic favorable (3.30e-5)" "unprognostic (1.51e-2)" "unprognostic (3.11e-1)" "unprognostic (6.00e-2)" "unprognostic (1.76e-2)" 30.8 24.7 39.3 10.9 33.5 20.7 28.8 48.8 48.5 40.6 3.3 36.3 11.6 33.2 15.5 45.1 34.1 15.9 53.5 40.4 31.6 24.8 17.4 33.6 14.0 37.6 41.1 45.0 22.5 31.5 48.1 22.6 35.1 29.2 7.3 24.3 22.9 15.1 77.5 71.3 22.9 14.8 22.4 26.4 24.0 19.7 40.0 10.4 30.8 28.6 11.6 29.2 37.0 50.3 8.7 5.5 14.9 3.5 28.2 21.7 53.6 22.8 56.1 11.3 18.1 12.3 9.1 13.5 9.0 54.4 16.5 6.9 17.6 9.8 4.7 21.2 28.7 26.3 18.6 28.6 12.2 8.7 35.7 31.2 16.5 12.8 15.8 19.0 9.3 10.6 20.0 26.5 65.5 6.7 14.3 26.2 16.4 6.7 13.0 54.7 41.6 35.4 1.2 3.8 38.6 20.3 6.7 27.6 31.2 21.8 39.3 49.6 5.1 27.8 17.5 6.6 11.7 43.6 39.7 16.2 16.0 10.7 13.4 11.6 9.2 9.7 5.4 13.5 3.8 7.2 4.3 5.4 11.1 7.5 4.5 4.0 20.9 4.5 16.8 9.7 4.1 7.3 39.3 33.5 48.8 48.5 40.4 31.6 37.6 41.1 35.1 22.4 40.0 50.3 24.0 12.8 13.7 11.1 20.4 29.2 32.3 9.0 26.2 87.8 23.8 21.3 27.1 30.0 11.9 20.2 118.9 21.9 19.6 22.4 21.5 17.2 20.2 17.1 10.7 22.1 46.0 9.3 18.9 8.7 53.1 24.1 10.2 25.1 12.6 47.0 24.3 9.3 22.7 82.4 31.0 14.9 6.1 18.5 17.8 10.0 48.4 29.8 14.2 12.2 16.5 18.9 11.3 14.1 26.2 11.5 16.5 43.6 14.2 41.2 21.5 7.3 12.4 60.4 65.7 31.8 40.1 4.2 32.7 28.1 32.8 218.1 17.0 29.9 11.3 25.3 HDLBP "HBP, VGL" ENSG00000115677 "High density lipoprotein binding protein" Q00341 2 241227264-241317061 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004189, CAB026457" Enhanced Supported Cytosol NA NA 95000 "Cluster 14: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB026457: , HPA004189: AB_1079044" "unprognostic (2.57e-2)" "unprognostic (1.13e-2)" "unprognostic (2.13e-2)" "unprognostic (1.51e-1)" "unprognostic (4.46e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.58e-5)" "unprognostic (1.70e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-2)" "unprognostic (4.39e-3)" "unprognostic (3.92e-2)" "unprognostic (9.48e-3)" "unprognostic (2.47e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (6.39e-5)" "prognostic unfavorable (4.12e-4)" 159.7 135.7 54.9 114.0 62.4 105.4 150.9 54.7 55.0 204.1 169.6 181.9 136.2 138.5 180.0 194.2 212.9 156.1 160.3 59.3 55.3 135.1 247.7 112.8 81.2 67.6 65.4 151.4 603.8 164.1 141.6 176.1 62.1 182.0 171.1 66.8 446.8 143.0 367.6 118.6 136.0 171.8 60.2 79.2 231.6 226.5 78.0 74.7 191.3 365.8 111.1 158.6 98.6 76.0 310.0 239.5 237.4 383.7 587.9 715.3 362.6 736.7 719.9 319.7 451.3 233.1 299.2 93.2 88.1 1039.3 334.0 235.2 356.9 465.8 528.2 150.4 236.0 323.0 305.1 535.7 566.7 233.0 251.4 528.8 369.1 466.0 515.9 500.4 448.1 140.9 310.1 120.0 511.9 309.5 120.4 106.1 237.9 290.4 161.2 111.7 511.9 175.5 255.1 380.1 208.4 223.5 332.3 334.5 278.4 304.2 262.6 201.8 585.4 402.1 255.1 551.5 325.3 136.2 130.8 166.5 488.1 161.1 371.8 26.0 39.3 17.4 15.6 41.0 20.3 19.6 17.7 18.8 41.3 12.7 15.5 15.1 22.0 19.2 58.1 26.4 18.1 27.5 54.9 62.4 54.7 55.0 59.3 55.3 67.6 65.4 62.1 60.2 78.0 76.0 53.9 76.9 102.7 38.5 60.6 70.2 117.4 80.4 150.2 41.0 125.3 98.8 220.5 71.4 124.9 75.4 43.8 133.9 34.7 176.2 135.0 106.7 111.0 152.8 178.3 80.8 96.5 72.6 44.5 122.1 166.5 156.3 203.4 168.2 68.4 199.3 86.7 199.3 94.6 69.0 45.9 291.1 30.5 70.3 66.4 398.0 148.8 75.1 56.9 46.9 77.8 53.5 20.6 46.3 58.1 116.5 118.4 174.9 354.7 203.9 136.3 117.9 163.3 40.0 65.7 126.5 117.0 132.1 120.7 192.4 77.6 215.5 50.7 134.0 163.2 156.1 HEG1 "HEG, KIAA1237" ENSG00000173706 "Heart development protein with EGF like domains 1" Q9ULI3 3 124965710-125055997 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 90.1;Cardiomyocytes: 90.5;Cone photoreceptor cells: 264.8;Endothelial cells: 121.5;Hepatic stellate cells: 130.3;Microglial cells: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 174.1;HHSteC: 241.5;hTERT-RPE1: 351.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010952, HPA011559" Approved Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 510000000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA010952: AB_2668389, HPA011559: AB_1850580" "unprognostic (1.10e-1)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.48e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (9.80e-2)" "unprognostic (1.69e-1)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (1.11e-2)" "unprognostic (4.99e-2)" "unprognostic (6.20e-3)" "prognostic unfavorable (1.16e-4)" 30.1 9.9 19.3 19.2 23.2 1.9 14.8 27.0 15.0 20.8 28.3 11.9 8.0 19.2 6.2 16.1 13.2 38.9 67.3 14.3 22.7 15.2 7.5 55.1 16.5 32.0 28.1 12.4 31.6 16.1 3.6 33.4 28.6 13.9 12.2 46.8 7.7 14.6 14.3 5.2 9.4 25.4 27.3 17.9 9.8 13.5 30.3 8.6 52.2 24.2 15.7 30.0 10.1 30.6 7.0 7.1 54.7 4.2 73.2 58.7 21.1 64.9 90.1 72.6 83.5 58.5 1.0 2.8 43.8 174.1 52.3 15.3 7.4 31.6 97.9 6.5 3.7 1.3 42.3 8.4 241.5 1.8 80.6 77.8 10.1 87.4 21.5 351.3 69.3 5.0 0.1 1.0 25.7 1.3 2.8 0.1 10.1 0.1 5.5 4.8 41.0 0.2 14.6 1.2 1.0 5.6 134.8 10.6 6.4 55.1 24.2 4.3 93.9 37.7 41.3 150.5 29.1 6.9 19.7 0.4 76.8 6.5 82.4 1.1 0.1 0.0 1.9 1.7 1.1 0.5 0.6 1.7 0.4 0.3 1.2 0.8 0.0 3.9 1.9 0.4 0.2 0.5 19.3 23.2 27.0 15.0 14.3 22.7 32.0 28.1 28.6 27.3 30.3 30.6 90.1 86.6 5.8 28.7 4.9 5.0 8.0 25.4 6.8 6.1 2.4 5.7 90.5 7.2 6.5 27.6 264.8 1.8 19.2 0.5 0.0 32.0 7.0 4.0 20.1 121.5 0.0 6.1 0.9 6.4 65.3 44.8 1.1 2.2 26.6 24.9 130.3 3.5 6.8 1.7 14.9 0.5 4.1 18.4 7.3 9.4 5.0 7.1 7.2 92.8 4.0 6.0 35.0 13.0 57.6 6.4 0.1 13.9 8.6 5.2 0.8 1.3 1.0 66.8 0.0 24.0 28.7 1.0 1.1 2.7 4.4 3.3 14.2 3.1 0.1 1.3 HERC3 KIAA0032 ENSG00000287542 "HECT and RLD domain containing E3 ubiquitin protein ligase 3" 4 88523810-88708450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.5;Excitatory neurons: 73.2;Inhibitory neurons: 101.6;Oligodendrocytes: 113.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA039170 Uncertain Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA039170: AB_10673414" 1.0 0.9 1.4 1.4 1.2 2.1 1.3 1.9 1.6 2.1 2.1 1.2 0.8 0.9 0.9 1.5 0.8 0.8 2.4 0.9 1.5 1.5 1.3 1.2 1.4 1.8 1.3 1.1 0.6 5.0 1.1 1.8 2.5 1.6 8.5 1.7 1.8 0.9 1.5 0.7 0.9 1.0 1.7 1.2 0.4 1.3 2.1 1.5 1.9 2.1 1.2 1.4 1.9 0.0 0.3 0.5 0.6 4.5 0.5 1.4 4.1 1.8 1.5 0.4 1.4 2.3 0.3 4.6 1.0 0.3 0.0 1.3 1.9 0.4 0.5 1.6 0.1 0.5 0.6 3.4 2.2 1.8 1.9 1.7 5.1 0.9 3.0 0.6 0.7 0.9 3.6 0.0 1.7 0.3 0.0 0.4 0.3 1.8 1.6 0.9 2.3 0.0 0.4 0.7 0.5 0.6 0.8 0.6 0.3 0.5 3.3 1.8 0.7 0.3 2.1 1.4 0.0 0.7 1.5 1.4 0.9 0.0 0.5 0.3 0.3 0.4 0.4 0.3 0.5 0.3 0.6 0.1 0.7 0.8 0.9 0.4 0.7 0.0 0.8 0.4 1.4 1.2 1.9 1.6 0.9 1.5 1.8 1.3 1.8 1.0 1.3 1.4 8.6 6.4 6.9 35.9 15.5 35.9 10.6 7.6 9.6 23.9 11.3 3.8 0.0 5.7 5.5 9.2 110.5 0.0 11.0 14.6 1.9 4.1 3.6 5.2 7.0 7.3 27.6 8.2 73.2 9.1 0.0 8.1 9.2 9.5 15.8 3.4 7.9 13.5 0.0 32.0 101.6 8.9 8.2 22.3 22.0 3.0 8.4 17.9 14.2 68.4 14.1 14.0 8.2 57.3 113.9 10.9 8.2 13.2 12.3 11.6 10.5 9.2 7.2 70.0 6.6 11.1 8.5 3.5 6.7 16.3 50.7 0.0 16.7 4.9 6.1 11.2 HERC4 "DKFZP564G092, KIAA1593" ENSG00000148634 "HECT and RLD domain containing E3 ubiquitin protein ligase 4" Q5GLZ8 10 67921899-68075301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 174.9;Oligodendrocytes: 209.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 201.4;fHDF/TERT166: 226.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045453, HPA070301" Uncertain Supported "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Nucleoli fibrillar center" "HPA045453: AB_10961917, HPA070301: AB_2686247" "unprognostic (3.66e-2)" "unprognostic (6.31e-2)" "unprognostic (1.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.42e-1)" "unprognostic (4.23e-2)" "unprognostic (3.51e-2)" "unprognostic (1.01e-3)" "unprognostic (3.54e-1)" "unprognostic (8.57e-2)" "unprognostic (4.94e-3)" "unprognostic (2.25e-2)" "prognostic unfavorable (3.86e-5)" "unprognostic (1.17e-1)" "unprognostic (2.40e-1)" "unprognostic (3.98e-1)" "unprognostic (2.31e-2)" 13.9 19.6 18.2 14.4 18.9 10.9 14.3 19.5 23.5 15.2 15.3 14.1 13.8 14.9 14.0 14.5 13.4 13.3 13.6 20.6 22.4 13.7 16.6 13.9 21.0 19.4 19.7 15.3 11.1 12.0 14.1 16.5 19.4 12.2 15.9 13.9 11.5 11.4 13.5 13.4 14.6 15.6 18.1 18.2 11.6 14.2 21.1 15.2 13.1 12.3 19.4 16.2 14.3 26.7 75.4 30.4 16.7 28.5 47.5 63.9 15.5 201.4 125.5 75.5 47.6 17.5 35.3 29.7 14.3 226.7 40.6 40.9 21.1 28.9 102.0 17.6 9.2 13.7 51.3 12.2 22.6 17.3 21.3 30.2 33.8 39.3 34.4 89.1 47.5 15.0 14.9 14.3 117.4 35.2 11.3 19.9 9.9 15.8 49.0 15.3 7.6 8.2 32.3 23.7 8.7 9.4 66.1 26.4 26.5 37.6 15.4 20.1 65.0 38.2 17.5 94.7 31.9 8.7 11.2 17.8 67.7 32.3 13.6 10.8 5.0 6.6 3.9 4.1 5.0 3.4 4.1 4.5 5.7 3.4 4.1 4.2 6.7 5.2 4.1 1.6 5.6 3.7 18.2 18.9 19.5 23.5 20.6 22.4 19.4 19.7 19.4 18.1 21.1 26.7 29.8 48.1 29.3 127.0 41.0 50.3 33.7 27.2 26.2 50.1 29.1 16.6 23.0 14.3 24.1 18.4 43.8 29.3 38.7 78.7 7.9 19.5 66.4 44.3 45.4 30.9 22.1 32.4 170.2 12.2 40.8 30.3 34.1 70.9 30.4 31.3 28.5 24.5 23.6 53.8 148.8 29.9 26.4 42.9 23.3 47.4 26.8 30.9 17.8 149.9 36.0 18.9 40.2 174.9 209.2 38.6 52.3 19.2 17.4 42.6 37.8 24.9 25.5 45.8 6.6 33.2 28.1 25.2 12.4 23.4 60.9 15.6 40.9 38.5 21.9 48.5 HHIPL1 KIAA1822 ENSG00000182218 "HHIP like 1" Q96JK4 14 99645129-99680569 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.7" "Cell type enhanced" "Detected in some" "Astrocytes: 33.3;Bipolar cells: 10.5;Excitatory neurons: 8.3;Inhibitory neurons: 12.2;Muller glia cells: 13.1;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.1;fHDF/TERT166: 5.6;SiHa: 3.7;THP-1: 3.9" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA 120000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (6.16e-2)" "unprognostic (3.44e-2)" "unprognostic (3.43e-2)" "unprognostic (1.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (2.75e-2)" "unprognostic (4.70e-3)" "unprognostic (6.68e-2)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.35e-3)" "unprognostic (8.49e-6)" "unprognostic (2.52e-2)" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (7.12e-6)" 1.6 0.3 7.0 1.1 8.7 0.1 0.8 4.1 8.4 1.5 3.0 2.0 0.5 2.5 0.4 0.8 1.3 1.2 1.6 7.2 4.6 0.7 0.6 0.7 1.0 4.9 4.7 1.0 0.2 0.3 0.9 0.6 4.5 1.7 0.3 2.1 0.8 0.9 0.3 0.5 0.9 1.8 4.0 0.9 0.8 0.4 6.3 0.1 0.5 0.4 0.6 1.3 1.1 4.2 0.0 0.2 0.4 0.1 0.1 0.0 1.7 1.6 0.4 0.3 0.1 0.1 0.5 0.1 3.1 5.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.0 0.0 0.9 0.1 1.2 0.2 0.1 1.4 0.1 0.0 0.1 0.9 0.2 0.0 0.2 1.2 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.6 3.7 0.0 0.0 0.6 0.0 3.9 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 8.7 4.1 8.4 7.2 4.6 4.9 4.7 4.5 4.0 6.3 4.2 1.6 0.0 0.0 33.3 0.1 0.0 0.0 0.0 0.0 10.5 0.3 0.8 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 2.0 1.7 0.0 0.0 8.3 0.0 0.1 2.6 0.0 0.0 0.0 0.9 0.7 0.3 1.9 0.0 12.2 0.0 0.0 2.1 0.7 0.2 0.3 0.3 3.6 6.5 0.0 13.1 0.0 13.0 6.2 0.0 1.4 1.9 0.0 0.1 0.1 0.0 0.0 1.7 0.0 0.9 0.9 0.3 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.1 HIC1 "ZBTB29, ZNF901" ENSG00000177374 "HIC ZBTB transcriptional repressor 1" Q14526 17 2054154-2063241 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding, Repressor" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 38.6;Fibroblasts: 44.3;Leydig cells: 57.5;Peritubular cells: 48.2;Sertoli cells: 46.0;Smooth muscle cells: 30.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.9" "Lineage enhanced" "Detected in single" "granulocytes: 1.9" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.9;BJ: 11.9;HSkMC: 7.1;TIME: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043372 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043372: AB_10795614" "unprognostic (1.93e-1)" "unprognostic (9.27e-2)" "unprognostic (6.63e-2)" "unprognostic (4.27e-3)" "unprognostic (2.06e-1)" "unprognostic (1.87e-2)" "unprognostic (3.08e-1)" "unprognostic (6.45e-2)" "unprognostic (8.58e-2)" "unprognostic (2.06e-2)" "unprognostic (1.73e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (9.36e-6)" "unprognostic (2.20e-2)" "unprognostic (3.92e-2)" "unprognostic (1.00e-1)" "unprognostic (5.14e-2)" 24.5 8.6 5.0 5.7 4.0 1.3 16.5 3.4 3.8 23.9 2.8 16.1 6.5 27.0 1.5 5.7 21.5 4.4 23.4 3.0 3.1 12.4 5.9 15.2 2.1 5.7 4.5 30.0 3.8 0.9 19.7 1.4 4.1 20.1 1.7 0.5 5.2 4.5 8.5 5.3 11.7 3.2 3.9 8.9 9.8 4.9 5.6 2.3 12.6 1.2 0.5 17.9 13.9 2.4 0.6 0.7 0.8 0.6 4.7 6.9 1.4 11.9 6.4 1.6 2.3 0.6 0.3 0.1 0.2 6.2 0.6 1.1 0.7 0.2 0.5 0.4 1.5 0.3 0.8 0.3 4.0 0.2 0.5 7.1 0.8 2.4 0.1 3.3 6.2 0.6 1.8 2.8 0.4 0.0 0.1 0.4 0.2 0.0 0.4 0.7 0.3 0.3 0.2 0.4 0.4 0.7 0.2 0.1 0.0 0.2 0.0 0.1 12.4 4.3 0.1 4.2 6.2 0.4 0.4 0.2 0.4 0.4 1.1 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.0 4.0 3.4 3.8 3.0 3.1 5.7 4.5 4.1 3.9 5.6 2.4 25.6 0.0 1.8 1.0 3.9 4.0 2.1 1.5 1.2 2.1 1.9 1.8 5.8 0.0 1.0 1.8 0.0 0.1 19.2 0.1 0.0 0.5 0.5 2.0 38.6 26.9 1.8 0.4 0.2 1.1 0.7 44.3 1.1 1.6 2.5 0.2 23.9 0.3 0.5 0.0 0.3 0.1 2.0 8.5 6.0 1.6 57.5 15.5 3.6 6.5 0.2 0.3 12.3 0.0 0.0 0.2 0.1 48.2 2.3 1.1 0.2 0.1 1.0 1.6 46.0 12.5 30.1 0.8 2.9 1.1 4.1 0.1 13.0 13.3 0.0 2.6 HSPB3 HSPL27 ENSG00000169271 "Heat shock protein family B (small) member 3" Q12988 5 54455699-54456377 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "heart muscle: 406.9;skeletal muscle: 217.2;tongue: 218.9" "Cell type enriched" "Detected in some" 18 "Cardiomyocytes: 398.1" "Cancer enriched" "Detected in many" 6 "head and neck cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 86.3;fHDF/TERT166: 39.1;HSkMC: 16.3;LHCN-M2: 12.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA062124 Supported "Nuclear speckles" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA062124: AB_2684690" "unprognostic (1.44e-1)" "unprognostic (2.21e-1)" "unprognostic (1.78e-3)" "unprognostic (3.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.13e-1)" "unprognostic (4.41e-3)" "unprognostic (6.42e-2)" "unprognostic (1.85e-1)" "unprognostic (2.70e-2)" "unprognostic (2.73e-1)" "unprognostic (2.82e-2)" "unprognostic (7.15e-2)" 1.4 0.2 4.6 0.1 5.6 0.2 2.1 4.0 7.5 0.9 4.1 5.2 0.2 7.5 0.4 16.5 3.0 0.2 406.9 6.3 7.2 0.4 0.1 2.8 0.0 4.1 4.0 1.0 0.1 0.0 3.6 0.1 4.4 8.6 2.1 1.6 6.7 0.8 217.2 2.2 0.9 10.4 4.1 0.7 0.9 1.8 4.1 0.7 0.3 218.9 0.0 3.7 0.8 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 86.3 0.1 0.1 0.4 0.0 0.0 0.3 39.1 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.0 16.3 5.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 5.6 4.0 7.5 6.3 7.2 4.1 4.0 4.4 4.1 4.1 6.4 0.0 0.0 0.0 0.3 0.0 6.4 0.4 3.2 0.0 0.1 0.0 0.0 398.1 0.0 0.3 0.0 0.0 0.1 0.0 10.5 0.0 0.0 0.1 0.7 0.2 3.5 0.0 0.0 4.3 0.0 0.0 14.4 0.0 1.3 0.0 0.1 0.0 0.0 0.1 1.7 6.5 0.0 0.0 0.0 4.9 0.4 0.6 0.2 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 6.6 21.3 7.2 0.4 0.0 0.0 5.3 0.1 0.2 0.1 0.3 0.3 HSPB7 cvHSP ENSG00000173641 "Heat shock protein family B (small) member 7" Q9UBY9 1 16014028-16019594 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 4135.3;skeletal muscle: 2417.8;tongue: 1229.5" "Cell type enriched" "Detected in some" 32 "Cardiomyocytes: 2389.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "fHDF/TERT166: 315.1" "Not detected" "Not detected" HPA027639 Approved Approved Nucleoplasm NA NA 130000 "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA027639: AB_10601756" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (1.28e-3)" "unprognostic (7.44e-3)" "unprognostic (8.35e-2)" "prognostic unfavorable (5.29e-4)" "unprognostic (1.02e-1)" "unprognostic (5.32e-2)" "unprognostic (2.47e-3)" "unprognostic (3.19e-3)" "unprognostic (6.94e-2)" "unprognostic (1.55e-1)" "unprognostic (1.20e-2)" "unprognostic (1.18e-2)" "unprognostic (1.51e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (1.26e-4)" 306.8 123.4 3.9 32.1 4.4 0.2 119.7 8.8 5.1 49.6 8.6 138.3 5.1 179.5 7.5 44.2 64.8 18.7 4135.3 4.1 5.6 38.5 3.2 22.1 1.7 13.1 7.9 25.4 9.2 38.8 5.3 7.1 12.0 43.0 8.0 3.1 35.1 24.4 2417.8 19.3 34.0 189.2 5.3 4.5 71.4 20.2 4.7 0.6 14.1 1229.5 0.7 99.2 30.5 6.7 0.0 0.0 0.0 1.5 70.7 3.2 1.8 18.4 1.1 0.0 0.2 0.0 0.1 0.0 0.0 315.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 3.4 0.0 0.0 2.1 0.0 0.0 0.0 7.9 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.6 0.1 0.1 0.0 0.1 5.3 3.3 0.0 0.0 0.0 1.3 0.0 11.8 0.0 1.3 0.1 1.1 0.0 14.1 0.6 1.9 0.0 10.3 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.4 8.8 5.1 4.1 5.6 13.1 7.9 12.0 5.3 4.7 6.7 0.5 0.0 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.8 0.2 0.4 2389.7 0.0 0.0 3.7 0.0 2.8 0.0 0.0 13.7 1.4 55.5 0.1 0.7 26.6 0.0 0.0 0.0 0.2 1.4 46.3 0.0 0.1 0.0 0.4 0.0 0.0 1.6 1.7 0.1 0.0 0.0 0.0 4.6 74.2 14.3 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.2 0.0 0.0 6.8 0.0 0.5 0.0 0.2 0.0 0.6 0.0 20.2 42.6 1.9 0.9 0.1 2.6 3.3 0.5 3.0 0.0 0.1 IBSP "BSP, BSP-II, SP-II" ENSG00000029559 "Integrin binding sialoprotein" P21815 4 87799554-87812435 "Cancer-related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;pituitary gland: 2.0" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 5.8" "Group enriched" "Detected in many" 4 "breast cancer: 3.8;glioma: 12.2" "Region enhanced" "Detected in single" "thalamus: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-138 MG: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.53e-2)" "unprognostic (3.55e-2)" "unprognostic (1.49e-2)" "unprognostic (3.93e-1)" "unprognostic (3.75e-2)" "unprognostic (9.48e-3)" "unprognostic (1.03e-3)" "unprognostic (4.07e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-11)" "unprognostic (6.20e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-3)" "unprognostic (2.11e-1)" 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 2.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.5 0.7 0.7 0.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IGFBP3 "BP-53, IBP3" ENSG00000146674 "Insulin like growth factor binding protein 3" P17936 7 45912245-45921874 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 1864.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 457.7;Basal respiratory cells: 777.7;Extravillous trophoblasts: 2064.1;Fibroblasts: 463.4;Urothelial cells: 809.9" "Cancer enhanced" "Detected in all" "renal cancer: 377.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 54.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 54.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 8578.6;U-2197: 3469.4;U-87 MG: 1774.2" "Low region specificity" "Detected in all" CAB010360 Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3250000000 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB010360: AB_2233528" "unprognostic (4.46e-3)" "unprognostic (4.84e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.30e-1)" "unprognostic (1.15e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (8.14e-3)" "unprognostic (3.31e-2)" "unprognostic (2.03e-1)" "unprognostic (9.67e-3)" "unprognostic (2.80e-1)" "prognostic unfavorable (5.07e-7)" "unprognostic (2.36e-2)" "unprognostic (4.14e-2)" "unprognostic (2.37e-3)" "unprognostic (2.63e-1)" 350.6 16.2 15.6 28.5 20.2 1.2 278.2 12.2 24.1 291.8 18.9 96.7 67.8 547.3 43.1 28.2 130.9 44.6 284.6 16.5 22.5 65.9 721.3 37.5 68.3 20.7 13.7 233.1 14.4 28.0 98.1 1864.4 21.0 87.4 58.4 11.9 46.2 81.1 57.9 176.5 77.9 198.1 12.8 191.0 81.7 10.8 16.5 18.2 40.8 73.3 67.4 369.7 165.3 15.9 199.6 59.5 113.1 1.0 83.9 34.7 0.9 850.6 153.8 71.9 38.8 0.2 157.4 0.2 263.2 8578.6 35.6 466.5 1.5 3.4 29.2 0.6 0.1 0.3 20.8 0.2 21.9 0.4 1.6 285.7 12.8 15.1 53.8 112.3 0.7 0.0 0.1 3.2 26.8 1.2 1.3 1.4 7.8 1.8 10.9 0.8 0.4 81.4 53.2 423.6 13.6 32.7 293.9 11.4 15.3 250.6 1.5 0.7 0.5 815.4 1.7 3469.4 49.3 11.6 0.7 1.1 1774.2 0.3 282.1 0.0 0.0 0.0 10.1 0.0 8.0 0.0 10.9 10.7 0.0 0.0 4.9 8.1 0.1 0.0 0.0 54.5 0.8 4.5 15.6 20.2 12.2 24.1 16.5 22.5 20.7 13.7 21.0 12.8 16.5 15.9 260.4 3.2 3.9 0.7 1.9 457.7 148.9 777.7 8.0 2.8 12.6 30.4 12.6 8.6 409.7 228.1 0.0 94.1 10.0 0.7 11.7 145.6 1.3 32.3 220.1 168.0 273.7 5.3 2.5 2.0 2064.1 463.4 1.5 31.3 1.3 12.2 182.0 2.6 80.9 0.0 5.6 8.4 57.0 7.2 21.9 3.5 288.3 3.5 16.0 1.9 7.2 0.6 0.0 0.5 0.2 19.0 2.5 6.8 1.0 212.1 0.8 1.0 136.0 0.5 0.0 12.6 124.6 0.8 1.4 9.3 244.6 154.2 9.3 3.6 2.0 809.9 IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695549 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1492.5;ovary: 1323.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 1104.1;Ionocytes: 980.6;Leydig cells: 1828.2;Peritubular cells: 981.7;Sertoli cells: 1275.3;Skeletal myocytes: 2750.9;Smooth muscle cells: 1376.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 831.3;BJ hTERT+: 2192.6;T-47d: 531.7;U-138 MG: 710.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059827, HPA070407" Supported Approved "Nuclear bodies,Golgi apparatus,Vesicles" "Secreted to blood" NA NA 110000000 380000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "Nuclear bodies" "HPA059827: AB_2732640, HPA070407: " "unprognostic (7.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (1.12e-1)" "unprognostic (2.41e-2)" "unprognostic (4.04e-2)" "unprognostic (9.62e-3)" "unprognostic (1.55e-1)" "unprognostic (3.28e-2)" "unprognostic (1.91e-3)" 375.1 221.8 35.6 178.2 35.1 0.7 354.6 21.9 30.9 1492.5 46.9 232.3 35.0 837.7 121.3 166.4 953.0 129.3 155.0 50.4 41.8 479.1 34.2 78.2 71.3 36.3 37.9 1323.4 30.7 30.7 272.8 290.7 31.5 241.4 66.2 105.4 111.0 121.8 470.9 129.0 139.3 621.2 28.1 38.7 323.5 28.8 43.8 95.0 326.2 292.9 45.9 259.2 382.9 62.4 0.0 0.0 210.6 0.9 237.1 7.5 0.8 831.3 2192.6 108.8 10.4 0.0 1.0 0.1 3.3 2.3 0.0 0.1 26.2 0.0 5.6 0.1 8.2 218.1 4.4 0.2 103.1 0.1 1.8 33.1 0.0 14.7 0.1 24.8 0.1 0.2 0.7 0.1 0.5 70.9 0.9 1.2 2.3 0.0 3.4 0.3 0.8 1.2 70.3 249.1 14.5 8.5 14.6 100.4 0.0 12.8 531.7 0.1 80.3 710.2 42.2 109.3 41.0 0.7 0.1 0.1 1.4 0.1 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.6 35.1 21.9 30.9 50.4 41.8 36.3 37.9 31.5 28.1 43.8 62.4 237.3 3.2 4.4 40.1 20.6 102.5 13.5 211.0 25.0 8.7 73.9 199.9 92.0 5.7 251.6 112.2 6.2 3.9 1.7 0.0 5.9 10.3 8.4 140.2 250.7 120.8 0.0 0.0 6.0 0.0 4.5 1104.1 30.5 128.5 2.5 11.4 49.6 1.4 8.7 3.3 13.7 0.0 980.6 0.6 189.7 39.9 1828.2 18.4 101.4 29.0 0.6 674.4 0.0 5.5 0.4 2.2 0.0 981.7 5.5 17.0 0.0 1.1 120.9 18.7 1275.3 2750.9 1376.0 2.2 3.0 17.7 67.9 5.6 18.4 124.7 0.1 16.8 IKBIP "FLJ31051, IKIP" ENSG00000166130 "IKBKB interacting protein" Q70UQ0 12 98613405-98645113 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 28.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 28.1" "Cell line enhanced" "Detected in all" "BJ: 206.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038677, HPA038678, HPA061541" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA038677: AB_2676146, HPA038678: AB_10672723, HPA061541: AB_2684555" "unprognostic (3.06e-1)" "unprognostic (1.06e-3)" "unprognostic (2.13e-1)" "unprognostic (4.34e-2)" "unprognostic (1.94e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (4.00e-5)" "unprognostic (6.28e-3)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (7.37e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.60e-9)" "unprognostic (7.37e-2)" "unprognostic (1.66e-1)" "unprognostic (3.46e-1)" "unprognostic (3.16e-2)" 14.0 7.1 2.3 15.3 2.8 5.1 10.1 2.3 3.1 12.6 5.0 6.6 4.1 10.3 5.8 4.8 6.7 12.9 9.3 2.3 2.9 8.3 10.3 11.0 12.6 3.2 2.7 5.9 5.8 4.2 7.7 26.8 3.2 6.8 7.0 1.2 6.1 7.4 2.6 3.1 5.7 16.0 2.9 11.8 5.6 4.6 3.1 11.6 9.3 4.8 9.6 17.1 7.4 3.7 13.0 39.8 43.5 28.4 102.8 105.8 39.4 206.0 124.7 53.3 67.2 8.8 12.4 42.4 35.5 128.7 37.1 26.7 17.5 80.5 90.1 12.4 26.7 16.2 23.9 59.8 39.3 30.2 31.1 81.1 16.6 62.4 54.5 95.3 75.3 7.8 25.5 16.0 133.3 11.8 14.0 68.7 16.9 10.2 33.5 11.9 64.0 21.7 88.9 14.6 6.6 20.8 58.9 4.1 34.1 73.6 13.1 37.0 71.6 115.7 41.3 50.5 53.9 17.2 20.1 31.8 33.3 27.2 85.1 11.4 6.4 19.3 2.8 4.9 3.3 5.9 1.8 2.9 5.4 3.8 2.0 2.0 28.1 5.0 5.7 3.7 2.6 1.8 2.3 2.8 2.3 3.1 2.3 2.9 3.2 2.7 3.2 2.9 3.1 3.7 44.9 12.8 15.7 1.6 34.4 7.6 15.5 55.6 21.6 2.8 7.9 22.4 3.0 0.0 18.7 3.7 4.2 35.5 32.5 2.3 11.7 10.5 2.8 7.9 47.4 47.7 0.0 19.8 5.9 5.8 65.3 47.0 2.6 4.4 20.8 32.7 44.3 8.4 45.7 3.3 3.3 4.8 12.2 31.2 34.1 3.6 30.7 35.4 14.2 14.0 40.4 2.0 37.0 11.6 2.2 5.1 3.1 17.0 74.8 7.6 1.0 10.1 6.3 2.6 39.5 27.8 46.8 32.1 16.0 9.0 7.2 10.1 23.6 25.3 2.9 6.5 IL11 "AGIF, IL-11" ENSG00000095752 "Interleukin 11" P20809 19 55364382-55370463 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Pancreatic endocrine cells: 64.4;Smooth muscle cells: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 50.9;BJ hTERT+: 60.0;HBF TERT88: 39.0;hTEC/SVTERT24-B: 47.9;U-251 MG: 187.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 34800 "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (6.60e-3)" "unprognostic (7.23e-3)" "unprognostic (1.12e-1)" "unprognostic (3.18e-3)" "unprognostic (3.32e-3)" "unprognostic (6.33e-2)" "unprognostic (1.04e-2)" "unprognostic (7.84e-5)" "unprognostic (2.47e-1)" "unprognostic (2.52e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (4.83e-2)" "unprognostic (4.07e-8)" "unprognostic (1.23e-1)" "unprognostic (1.41e-1)" "unprognostic (3.82e-3)" "unprognostic (3.08e-2)" 0.7 0.2 1.1 3.6 0.6 0.9 0.3 2.2 1.3 0.3 0.3 1.0 0.2 2.9 0.3 1.2 0.2 2.8 0.5 0.6 2.6 4.7 0.2 1.2 0.0 3.3 2.6 0.4 0.3 0.0 4.4 1.1 2.6 2.7 0.1 0.5 0.6 0.6 0.0 1.5 0.5 0.3 1.3 0.3 3.7 1.7 2.9 0.3 0.1 0.0 0.1 2.4 0.5 0.5 2.3 1.4 0.5 0.9 0.0 0.0 0.5 50.9 60.0 26.6 35.2 1.2 1.3 0.7 2.5 5.1 14.4 3.0 0.3 1.4 39.0 2.4 1.7 0.2 4.3 3.8 3.1 0.0 0.3 0.3 1.5 47.9 0.3 12.4 0.0 0.2 0.4 1.8 3.4 1.5 0.1 0.4 1.2 2.1 4.2 0.2 16.9 0.3 0.4 0.5 2.9 2.0 6.8 1.2 1.4 6.8 0.8 0.3 0.7 16.1 20.0 0.2 187.4 1.0 2.5 0.4 33.9 0.4 8.9 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 1.1 0.6 2.2 1.3 0.6 2.6 3.3 2.6 2.6 1.3 2.9 0.5 0.3 0.0 0.5 0.3 0.3 3.2 0.6 4.4 1.2 1.7 0.4 1.8 1.1 0.0 0.6 0.0 0.0 0.2 0.0 0.3 0.0 12.7 0.9 3.6 1.8 0.5 0.0 0.0 0.6 2.8 1.2 12.7 0.0 5.6 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.1 0.0 0.0 0.3 0.0 0.0 0.6 1.8 0.0 1.0 0.2 0.0 0.0 0.1 64.4 1.2 1.5 0.0 1.3 0.0 0.2 0.4 0.6 0.0 0.4 51.8 0.4 1.6 0.5 0.6 0.3 0.2 0.0 0.3 0.9 IL19 "IL-10C, IL-19, MDA1, NG.1, ZMDA1" ENSG00000142224 "Interleukin 19" Q9UHD0 1 206770764-206842979 "Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 20.0;salivary gland: 6.9" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 11.3;Breast glandular cells: 3.2;Club cells: 9.6;Endometrial ciliated cells: 2.9;Glandular and luminal cells: 5.2;Ionocytes: 4.1" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "BJ hTERT+: 9.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 172000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (6.21e-2)" "unprognostic (3.84e-2)" "unprognostic (3.55e-1)" "unprognostic (2.17e-2)" "unprognostic (2.48e-5)" "unprognostic (1.07e-1)" "unprognostic (8.72e-3)" "unprognostic (8.42e-2)" "unprognostic (2.04e-3)" "unprognostic (9.17e-2)" "unprognostic (7.20e-2)" "unprognostic (4.91e-2)" "unprognostic (2.78e-1)" 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 20.0 0.0 0.1 0.0 0.3 0.0 1.8 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.1 6.9 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.2 0.3 0.2 0.1 0.0 0.4 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.0 11.3 0.0 0.0 3.2 0.0 0.1 0.0 9.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.9 0.7 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 4.1 0.0 1.2 0.2 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 IL24 "C49A, FISP, IL-24, IL10B, mda-7, Mob-5, ST16" ENSG00000162892 "Interleukin 24" Q13007 1 206897443-206904139 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 15.2;lymphoid tissue: 25.5;urinary bladder: 14.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.8;Basal prostatic cells: 2.9;Fibroblasts: 11.6;Smooth muscle cells: 7.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 9.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 10 "B-cells: 5.4;T-cells: 3.6" "Cell line enriched" "Detected in some" 9 "BJ hTERT+: 172.7" "Not detected" "Not detected" "Not detected" "Not detected" CAB025972 Uncertain "Secreted to blood" NA NA 140000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB025972: " "prognostic favorable (5.09e-4)" "unprognostic (3.79e-1)" "unprognostic (2.89e-2)" "unprognostic (4.09e-3)" "unprognostic (3.98e-1)" "unprognostic (2.68e-1)" "unprognostic (2.85e-2)" "unprognostic (2.20e-2)" "unprognostic (3.98e-1)" "unprognostic (3.35e-2)" "unprognostic (8.04e-2)" "unprognostic (7.63e-2)" "unprognostic (3.43e-4)" "unprognostic (5.41e-2)" "unprognostic (1.29e-1)" "unprognostic (7.91e-2)" "unprognostic (3.33e-2)" 3.5 0.1 0.1 3.6 0.1 1.5 0.7 0.1 0.2 0.4 0.2 1.3 0.0 1.0 0.0 0.9 1.0 1.3 0.8 0.1 0.3 0.8 1.2 1.8 5.8 0.2 0.4 0.2 0.2 0.0 0.5 0.9 0.3 1.0 0.0 0.0 1.1 0.0 3.8 0.2 15.2 0.1 0.1 25.5 0.6 0.1 0.3 0.0 1.0 0.0 0.2 14.6 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 172.7 0.0 0.4 0.0 0.5 0.2 0.1 0.0 3.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.2 2.5 18.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 16.7 0.7 0.0 0.0 0.0 2.3 1.2 7.4 0.5 2.5 0.8 0.3 1.4 0.0 0.2 0.0 0.0 0.0 0.8 0.0 1.9 5.4 1.7 2.7 0.0 5.0 3.6 2.9 0.4 0.4 0.0 0.0 1.9 0.8 0.1 0.1 0.1 0.2 0.1 0.3 0.2 0.4 0.3 0.1 0.3 0.1 0.2 0.0 1.3 0.0 1.8 6.8 2.9 0.5 0.0 0.0 0.4 0.3 1.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.1 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.2 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 7.9 0.0 0.0 0.0 1.3 0.0 0.6 0.0 0.1 0.7 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 30000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: AB_2680391" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favorable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 108.0 77.2 49.8 85.1 52.4 43.7 91.8 51.7 50.6 151.6 55.0 398.2 66.4 359.1 81.8 115.5 164.2 88.0 175.9 47.4 50.7 78.8 65.9 107.9 72.4 51.8 50.6 101.0 89.3 73.2 47.1 98.8 50.9 182.7 116.8 28.3 69.5 412.2 90.8 61.5 117.4 364.7 51.1 95.5 149.7 26.5 53.7 45.8 72.0 92.0 70.5 226.7 118.8 51.9 127.8 94.4 148.9 51.8 224.8 159.4 67.2 182.2 360.0 211.9 256.0 102.7 145.7 47.0 47.0 304.1 206.9 99.5 84.4 155.6 213.0 83.5 74.3 69.1 84.9 82.8 150.8 55.9 74.7 153.2 72.8 143.8 108.9 217.7 206.9 40.5 63.7 55.0 282.8 97.1 49.4 97.4 94.3 107.5 110.8 51.0 77.8 50.5 160.3 100.8 25.6 57.4 86.0 118.4 103.6 144.0 82.2 62.2 238.8 263.9 118.0 111.1 90.7 38.9 25.9 67.1 195.6 82.8 125.3 314.9 260.0 417.6 127.3 258.1 124.9 96.9 114.4 122.3 242.7 92.9 70.2 88.5 165.5 257.8 254.8 98.5 142.8 402.8 49.8 52.4 51.7 50.6 47.4 50.7 51.8 50.6 50.9 51.1 53.7 51.9 79.5 44.8 17.9 24.2 33.6 50.5 73.7 100.6 24.5 21.5 43.1 68.2 0.5 70.1 49.7 57.0 8.4 119.8 46.0 71.9 58.7 136.1 64.6 33.2 78.1 69.4 37.9 53.7 14.6 125.0 177.7 83.2 50.4 52.5 30.4 41.6 76.4 31.4 127.4 8.4 17.1 50.1 69.2 51.5 97.7 143.7 71.4 115.9 85.4 30.9 143.0 54.3 77.2 15.6 15.3 117.1 60.0 147.4 35.1 42.0 74.5 98.6 31.0 32.9 157.8 53.3 165.8 31.7 17.1 32.3 43.2 110.0 49.3 65.0 50.1 43.9 INHBA ENSG00000122641 "Inhibin subunit beta A" P08476 7 41667168-41705834 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 21.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 94.4;Langerhans cells: 68.0;Leydig cells: 137.6;Smooth muscle cells: 218.3;Syncytiotrophoblasts: 178.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 75.9;hTEC/SVTERT24-B: 227.0;hTERT-HME1: 92.9;hTERT-RPE1: 139.2;TIME: 120.1;U-138 MG: 174.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 210000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (4.11e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (4.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.18e-2)" "prognostic unfavorable (4.34e-4)" "unprognostic (2.05e-2)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.44e-1)" "unprognostic (1.31e-1)" "unprognostic (1.23e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (7.91e-8)" "unprognostic (6.22e-3)" "unprognostic (1.11e-2)" "unprognostic (3.25e-2)" "unprognostic (3.18e-3)" 2.3 1.5 2.1 5.1 2.0 10.4 0.9 2.3 7.8 1.5 0.7 1.0 0.8 17.3 3.7 2.1 1.2 21.6 5.4 8.7 3.3 2.8 9.5 11.0 1.2 4.3 8.1 6.8 0.6 0.5 0.5 10.9 3.4 3.2 0.6 2.3 5.4 5.0 0.5 2.0 0.5 4.3 4.5 0.5 0.8 1.7 3.0 0.2 1.2 4.6 0.4 10.3 1.1 3.4 4.2 0.0 0.4 0.1 3.3 7.1 0.0 18.2 1.9 9.9 3.3 0.0 0.4 0.0 1.1 6.9 11.6 15.3 0.0 75.9 9.6 5.1 0.0 0.0 0.0 0.0 13.9 0.0 0.2 7.0 4.2 227.0 92.9 139.2 8.2 0.0 0.5 0.0 23.0 0.2 0.0 0.3 1.5 0.0 10.5 0.0 0.0 0.0 0.0 0.1 0.1 5.7 11.1 0.6 0.0 6.2 0.1 0.2 120.1 174.7 49.7 18.9 19.0 0.0 0.0 0.0 6.7 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 2.1 2.0 2.3 7.8 8.7 3.3 4.3 8.1 3.4 4.5 3.0 3.4 0.7 3.2 15.7 0.0 0.9 17.3 10.8 13.5 2.2 0.1 3.5 6.5 6.0 0.0 4.4 0.0 0.0 1.4 0.3 0.1 0.0 23.6 0.6 1.4 4.1 5.9 0.0 0.0 2.4 2.0 4.6 42.0 0.0 2.6 7.6 94.4 0.7 18.5 1.5 0.0 0.2 0.2 4.1 1.4 68.0 5.9 137.6 55.8 14.2 0.0 27.0 16.1 0.0 4.0 0.3 11.1 0.1 23.3 0.0 12.5 0.0 0.1 2.8 1.3 0.0 4.9 218.3 0.7 0.3 1.4 8.9 178.4 1.7 18.8 0.2 2.3 INSYN2B "C5orf57, FAM196B" ENSG00000204767 "Inhibitory synaptic factor family member 2B" A6NMK8 5 169861303-169980495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.5;breast: 6.9;salivary gland: 5.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "renal cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 38.0;HUVEC TERT2: 23.2;U-138 MG: 66.3;U-251 MG: 25.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047227 Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA047227: AB_2679992" "unprognostic (5.30e-2)" "unprognostic (9.76e-3)" "unprognostic (1.60e-1)" "unprognostic (2.16e-1)" "unprognostic (2.32e-1)" "unprognostic (1.92e-1)" "unprognostic (1.26e-3)" "unprognostic (2.31e-2)" "unprognostic (1.98e-2)" "unprognostic (3.31e-5)" "unprognostic (5.16e-1)" "unprognostic (1.19e-2)" "unprognostic (1.48e-2)" "unprognostic (2.37e-1)" "unprognostic (6.38e-2)" "unprognostic (3.73e-3)" 0.3 0.5 3.4 0.4 6.5 0.2 6.9 3.5 4.6 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 3.5 4.1 0.4 0.1 0.1 0.0 5.3 5.7 1.8 0.0 0.0 0.1 0.0 4.8 0.6 0.0 0.4 5.2 0.0 0.0 0.3 0.0 0.2 4.7 1.4 0.0 0.1 5.4 0.2 0.8 0.0 0.0 0.0 0.0 5.8 0.2 0.3 1.7 0.1 11.4 3.5 0.0 7.8 3.3 5.1 4.3 0.0 0.0 0.0 15.6 38.0 11.7 0.0 0.1 12.3 10.9 0.0 0.0 0.0 2.7 0.0 2.2 0.0 0.0 1.1 0.0 7.0 6.8 12.4 23.2 0.0 0.0 0.1 16.3 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 14.2 66.3 0.8 1.9 25.3 0.0 0.0 0.0 10.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.4 6.5 3.5 4.6 3.5 4.1 5.3 5.7 4.8 4.7 5.4 5.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IP6K1 "IHPK1, KIAA0263" ENSG00000176095 "Inositol hexakisphosphate kinase 1" Q92551 3 49724294-49786542 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040825 Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA040825: AB_10960426" "unprognostic (6.18e-2)" "unprognostic (1.33e-1)" "unprognostic (3.58e-2)" "unprognostic (4.71e-2)" "unprognostic (1.99e-1)" "prognostic favorable (2.08e-4)" "unprognostic (9.97e-3)" "unprognostic (8.45e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "prognostic favorable (6.85e-4)" "unprognostic (1.29e-2)" "prognostic favorable (5.77e-5)" "unprognostic (8.75e-2)" "unprognostic (1.67e-1)" "unprognostic (9.24e-2)" "unprognostic (1.64e-2)" 17.9 20.2 32.4 12.1 33.6 12.5 17.2 27.6 34.9 21.5 17.2 24.1 12.1 25.6 12.2 20.0 19.4 12.9 15.8 35.9 27.7 21.3 14.6 17.5 13.3 26.4 28.2 25.5 19.8 22.8 21.5 16.4 27.4 18.1 11.3 18.3 17.4 17.2 12.6 23.1 17.8 16.9 24.5 21.9 18.5 32.2 30.7 17.2 16.2 11.4 13.2 19.1 16.0 29.0 20.6 24.5 27.9 33.1 28.6 21.8 22.5 26.6 27.8 42.7 37.3 31.9 20.9 17.3 16.8 29.7 28.8 14.9 39.8 24.2 24.0 35.6 30.6 40.5 36.1 21.8 31.4 25.0 26.7 25.6 29.4 46.4 27.8 24.0 36.1 20.3 26.7 20.3 21.4 18.2 30.6 25.6 30.2 16.1 37.6 19.1 19.8 35.7 27.7 30.8 15.0 29.8 33.4 21.8 30.6 16.0 17.6 36.2 32.8 23.9 23.6 33.1 31.0 24.3 35.6 18.8 21.9 28.4 24.9 4.7 7.3 12.1 11.7 5.4 11.4 6.0 10.4 12.8 5.6 8.4 12.6 12.7 33.3 10.3 7.0 4.1 11.8 9.5 32.4 33.6 27.6 34.9 35.9 27.7 26.4 28.2 27.4 24.5 30.7 29.0 17.1 25.6 12.3 24.5 25.0 15.6 14.7 7.4 11.4 38.4 19.7 15.0 8.8 18.6 10.1 12.9 89.6 19.2 27.6 22.0 5.9 14.5 88.2 24.9 19.9 19.0 27.6 24.2 42.3 13.0 16.1 14.7 14.8 17.3 19.7 19.6 19.6 12.2 12.8 30.3 46.6 14.1 10.2 15.0 14.2 23.7 21.1 17.8 19.6 31.9 15.9 19.6 35.0 43.7 39.8 19.2 8.8 16.6 28.9 19.6 14.6 12.5 21.8 78.3 19.7 16.2 18.3 24.6 21.9 13.7 18.8 27.5 27.6 30.5 12.8 20.4 IPO5 "IMB3, KPNB3, MGC2068, Pse1, RANBP5" ENSG00000065150 "Importin 5" O00410 13 97953658-98024296 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 209.8" "Group enriched" "Detected in all" 11 "Early spermatids: 1152.2;Late spermatids: 2185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009110, HPA040983, HPA056548" Approved Supported Nucleoplasm,Cytosol NA NA 790000 "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "CAB009110: AB_2264985, HPA040983: AB_2677236, HPA056548: AB_2683169" "unprognostic (5.20e-2)" "unprognostic (6.94e-2)" "unprognostic (9.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.96e-3)" "unprognostic (2.16e-3)" "unprognostic (2.19e-2)" "unprognostic (5.27e-3)" "unprognostic (6.19e-2)" "unprognostic (2.51e-1)" "unprognostic (1.45e-1)" "unprognostic (1.06e-1)" "unprognostic (9.64e-2)" "unprognostic (1.82e-1)" "unprognostic (2.40e-1)" "unprognostic (1.66e-1)" "unprognostic (2.73e-1)" 53.0 27.4 20.2 37.8 26.8 37.6 44.9 20.3 31.9 46.3 14.9 36.9 23.9 45.2 27.3 41.7 45.1 30.1 60.5 28.2 20.0 44.4 42.6 28.6 42.9 20.9 20.0 76.4 63.3 36.8 17.1 36.1 20.5 35.4 40.0 41.4 31.5 47.1 135.1 25.8 24.9 57.9 21.7 30.0 31.8 209.8 18.6 48.5 55.3 115.6 54.8 45.6 23.7 29.2 168.9 111.8 205.0 188.7 136.4 344.0 124.7 241.8 190.3 334.3 235.7 231.4 127.0 485.4 82.3 294.2 75.4 142.5 430.0 166.6 456.6 123.6 135.8 265.1 197.4 183.0 97.4 287.3 90.8 194.5 107.6 271.9 225.4 142.3 193.3 147.0 186.3 63.9 288.1 46.8 219.2 78.4 206.0 253.3 132.3 277.9 232.5 143.4 79.6 109.3 151.0 123.5 123.8 143.6 90.9 247.2 109.5 156.9 137.4 224.0 111.8 113.6 223.3 84.2 102.9 146.8 230.4 179.6 156.9 0.5 5.0 1.3 7.0 8.2 12.3 7.8 8.3 9.1 11.7 7.6 11.5 9.7 0.4 11.4 5.8 5.7 9.3 6.8 20.2 26.8 20.3 31.9 28.2 20.0 20.9 20.0 20.5 21.7 18.6 29.2 27.0 19.2 27.8 27.7 27.0 41.4 45.9 24.3 44.3 32.9 29.9 22.4 76.6 40.0 22.3 22.0 6.2 41.0 19.9 14.5 27.4 31.8 1152.2 24.9 37.5 39.5 35.3 72.8 53.4 42.3 47.5 45.1 21.4 29.3 14.5 75.6 32.9 44.2 23.9 63.9 39.5 24.8 18.3 33.3 31.6 2185.2 52.8 24.7 26.6 14.0 28.4 44.3 16.5 27.6 36.1 35.3 11.9 44.0 46.5 79.4 9.5 42.7 20.7 22.6 26.3 63.7 49.0 142.9 57.8 40.7 36.9 32.3 23.6 47.2 41.1 39.7 IQCJ-SCHIP1 ENSG00000283154 "IQCJ-SCHIP1 readthrough" B3KU38 3 158962235-159897366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 165.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 7.3;Basal squamous epithelial cells: 12.5;Bipolar cells: 11.5;Excitatory neurons: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA003243, HPA003445" Approved Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA003243: AB_1079877, HPA003445: AB_1079875" 22.0 5.1 82.3 9.7 90.6 2.2 15.4 84.9 165.9 9.2 56.6 49.8 4.5 19.6 6.3 15.4 18.2 12.5 57.2 83.9 73.9 17.8 14.3 19.6 2.2 93.5 88.0 4.4 2.7 1.1 7.3 23.6 92.0 17.7 6.8 14.2 6.5 20.4 27.6 5.7 12.8 25.9 81.5 4.3 18.3 4.7 87.2 2.5 5.7 3.2 1.8 35.8 10.8 110.5 87.9 14.8 28.9 34.4 6.6 6.3 25.1 73.6 17.3 59.4 40.5 55.6 20.9 4.4 46.4 24.6 22.6 34.8 11.3 24.9 48.5 72.7 27.6 0.1 31.2 2.8 7.7 4.2 0.5 6.5 20.8 26.5 31.1 49.3 44.5 4.9 0.0 0.3 27.7 3.9 0.3 0.0 24.2 7.0 31.9 10.2 58.4 0.0 57.6 4.7 5.8 26.8 39.8 16.7 21.8 32.9 9.8 0.8 37.6 34.0 47.5 22.9 101.5 0.3 0.5 0.4 19.1 12.4 92.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 82.3 90.6 84.9 165.9 83.9 73.9 93.5 88.0 92.0 81.5 87.2 110.5 4.7 6.4 0.0 1.0 0.1 1.5 7.3 0.8 12.5 11.5 0.3 0.9 0.6 0.0 1.4 1.8 6.2 0.0 0.1 0.3 0.0 0.9 2.0 2.1 0.8 5.7 0.0 0.0 11.3 0.6 0.0 3.1 0.0 2.3 2.5 0.0 1.8 0.6 0.0 0.0 4.7 0.2 0.0 0.3 1.2 0.6 0.3 1.2 0.0 0.0 0.6 0.5 0.0 0.0 0.6 1.2 0.0 1.2 0.0 1.3 0.0 4.2 2.4 0.6 0.0 2.5 5.4 0.1 0.4 3.5 0.9 0.0 0.5 0.0 0.2 1.6 ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.6" "Cell type enhanced" "Detected in many" "Adipocytes: 264.1;Endothelial cells: 120.5;Hepatocytes: 110.5;Sertoli cells: 98.6;Smooth muscle cells: 143.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.5;HHSteC: 4.5;SH-SY5Y: 1.7;WM-115: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain NA NA 6300000 "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042555: AB_10794281" "unprognostic (1.48e-1)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.13e-3)" "unprognostic (2.06e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-2)" 13.9 22.4 0.6 1.0 0.8 0.0 10.2 0.7 0.9 5.1 0.4 36.6 1.1 16.3 2.5 5.7 9.9 2.2 10.6 0.5 0.8 11.0 17.1 22.1 0.8 0.8 0.8 3.6 3.1 2.1 2.3 5.8 0.8 12.6 2.7 0.1 2.3 7.2 4.6 2.3 12.5 5.8 0.8 27.9 16.6 0.8 0.8 0.2 9.7 2.5 0.4 17.9 5.1 0.9 0.0 0.0 0.3 0.0 1.4 0.4 0.1 0.3 1.3 0.3 0.7 0.7 0.0 0.0 0.1 4.5 0.5 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.3 0.3 4.5 0.0 0.0 0.7 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 1.7 0.5 0.0 0.0 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.7 0.9 0.5 0.8 0.8 0.8 0.8 0.8 0.8 0.9 264.1 54.5 26.8 2.9 1.7 3.2 4.7 1.5 2.8 1.8 3.6 13.8 12.6 5.7 8.7 5.5 2.1 1.5 2.9 5.5 1.9 3.0 21.3 7.7 41.8 120.5 16.4 5.3 3.6 5.4 16.8 40.2 6.1 22.1 10.1 1.0 77.1 110.5 2.2 0.0 19.5 14.0 0.0 7.2 8.2 6.1 9.3 5.6 7.2 63.7 9.1 0.4 0.0 1.5 4.2 19.6 7.7 8.2 2.9 3.2 6.5 15.1 6.3 2.0 98.6 18.6 143.9 0.9 1.1 0.5 3.1 3.4 46.0 13.6 14.0 2.3 ITGA11 HsT18964 ENSG00000137809 "Integrin subunit alpha 11" Q9UKX5 15 68296532-68432163 "Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 26.3;endometrium 1: 53.1;smooth muscle: 25.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 13.8;Excitatory neurons: 13.4;Fibroblasts: 30.1;Microglial cells: 18.7;Peritubular cells: 13.5;Sertoli cells: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "fHDF/TERT166: 119.5;hTERT-RPE1: 174.5;U-138 MG: 80.6;WM-115: 45.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 7.3;spinal cord: 2.1" HPA051813 Uncertain NA NA 260000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA051813: AB_2681622" "unprognostic (4.85e-2)" "unprognostic (3.51e-1)" "unprognostic (6.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.87e-2)" "unprognostic (3.07e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-2)" "unprognostic (9.29e-3)" "unprognostic (6.63e-2)" "unprognostic (5.68e-3)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.22e-7)" "unprognostic (8.38e-3)" "unprognostic (2.28e-4)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" 6.5 3.4 0.2 1.1 1.5 0.2 3.2 0.7 1.1 26.3 0.4 2.1 0.8 53.1 13.5 1.5 12.0 2.4 12.7 0.2 0.3 6.5 0.7 1.7 0.5 0.2 0.2 4.6 0.8 0.4 1.8 1.5 0.1 5.2 1.3 0.4 1.2 7.4 2.1 2.7 1.6 25.0 0.1 3.2 1.6 0.9 0.1 0.2 2.0 2.4 0.1 3.9 8.2 0.5 0.0 0.2 0.4 0.9 3.7 0.1 0.1 7.9 15.1 1.6 0.5 0.1 0.2 0.1 0.6 119.5 2.1 0.2 0.0 0.0 0.4 0.0 0.2 0.5 6.8 0.0 10.8 0.2 7.0 1.5 0.0 3.1 0.3 174.5 0.0 0.1 0.2 0.3 20.9 0.1 0.1 0.4 0.7 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.2 0.1 5.5 0.1 0.1 18.5 0.1 0.5 5.0 80.6 0.7 2.1 0.1 0.2 0.0 0.1 13.5 0.2 45.4 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 1.5 0.7 1.1 0.2 0.3 0.2 0.2 0.1 0.1 0.1 0.5 2.9 0.0 0.0 0.3 0.3 0.8 0.5 0.0 0.6 3.9 1.0 7.0 13.8 0.0 0.0 1.8 0.0 0.0 0.3 0.1 1.9 0.3 0.3 0.2 0.8 1.1 0.0 0.0 13.4 0.0 0.1 30.1 1.5 0.3 0.0 0.2 2.2 0.5 0.3 0.0 0.7 0.0 0.0 0.6 1.2 0.5 6.8 0.6 0.0 18.7 0.0 0.3 0.0 0.0 0.5 0.2 0.0 13.5 0.2 0.3 0.1 0.3 0.0 1.6 19.7 2.7 5.4 0.0 0.2 0.2 0.4 0.1 0.6 0.2 0.0 0.3 ITGB1 "CD29, FNRB, GPIIA, MDF2, MSK12" ENSG00000150093 "Integrin subunit beta 1" P05556 10 32887273-33005792 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1206.9;Pancreatic endocrine cells: 1393.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 2711.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003434, HPA059297, HPA069003" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Focal adhesion sites" NA NA 270000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Focal adhesion sites" "Endoplasmic reticulum" "CAB003434: AB_303570, HPA059297: AB_2732634, HPA069003: AB_2732125" "unprognostic (3.07e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.67e-2)" "unprognostic (4.36e-1)" "unprognostic (1.20e-2)" "unprognostic (3.87e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.22e-1)" "unprognostic (2.36e-3)" "unprognostic (3.68e-3)" "unprognostic (2.42e-1)" "unprognostic (1.02e-3)" "unprognostic (1.25e-2)" "unprognostic (2.23e-1)" "unprognostic (2.48e-1)" "unprognostic (3.08e-2)" 491.9 179.3 61.5 241.5 78.2 81.5 216.2 75.0 90.9 259.2 68.3 265.3 147.4 330.4 171.7 168.6 172.0 347.4 390.3 60.2 74.3 180.4 287.1 233.6 118.0 88.4 80.6 157.1 135.3 145.4 59.8 459.5 88.9 248.1 223.6 27.7 130.7 427.7 157.9 92.2 150.8 710.0 76.6 204.7 160.1 91.2 86.4 77.5 161.5 194.5 106.2 357.4 119.1 88.9 638.0 907.0 495.4 559.6 1183.4 1019.5 398.1 2063.9 1239.6 999.0 903.9 215.9 1478.2 164.5 354.1 1830.9 638.0 438.9 149.1 1204.1 1122.0 163.1 112.7 195.8 416.3 253.6 826.4 48.3 195.5 1027.7 658.2 1040.8 426.0 2711.1 1263.6 81.0 136.6 76.5 1700.8 109.0 80.1 46.7 107.4 200.6 428.2 52.0 357.0 30.9 1454.8 186.2 108.0 271.4 649.9 114.6 498.2 813.7 153.9 175.0 1362.6 1280.0 712.2 904.2 719.7 64.7 14.8 91.2 956.6 198.2 518.5 7.5 35.1 16.1 83.4 69.8 22.8 109.6 191.8 138.7 33.9 40.3 24.9 68.4 9.0 90.3 108.2 11.4 266.8 117.2 61.5 78.2 75.0 90.9 60.2 74.3 88.4 80.6 88.9 76.6 86.4 88.9 631.5 342.9 143.8 26.4 118.0 546.7 435.5 531.6 208.3 32.8 147.1 307.5 210.8 241.6 268.1 226.2 31.3 210.3 217.8 179.8 13.7 1206.9 6.6 194.6 437.9 421.1 193.3 153.0 37.2 411.3 515.2 374.7 95.8 406.5 88.7 561.8 375.9 268.1 179.8 38.7 52.4 97.4 213.6 170.1 206.7 18.3 254.5 217.8 343.3 67.5 119.4 72.0 111.2 42.7 66.8 1393.7 128.5 601.8 181.2 412.5 75.6 68.7 171.5 45.5 637.7 236.3 724.0 10.1 76.0 84.4 170.5 219.7 211.3 225.6 127.0 296.1 ITGBL1 "OSCP, TIED" ENSG00000198542 "Integrin subunit beta like 1" O95965 13 101452593-101720856 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 76.1;Skeletal myocytes: 93.0" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 208.3;ASC TERT1: 138.7;fHDF/TERT166: 345.3;LHCN-M2: 311.8" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 56.9" "Secreted - unknown location" NA NA 37000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.70e-1)" "unprognostic (2.12e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.12e-4)" "unprognostic (1.45e-1)" "unprognostic (3.18e-1)" "unprognostic (2.54e-1)" "unprognostic (1.86e-1)" "unprognostic (8.84e-2)" "unprognostic (2.16e-2)" "unprognostic (9.50e-2)" "unprognostic (1.13e-5)" "unprognostic (1.44e-2)" "unprognostic (2.55e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.70e-4)" 16.9 9.2 1.8 0.7 1.8 0.1 18.0 2.6 2.3 23.8 2.5 1.5 0.5 2.0 0.5 9.7 4.9 38.3 18.3 1.9 3.6 2.7 7.7 25.4 1.3 3.9 2.3 5.3 7.9 5.6 10.3 33.4 4.3 4.0 2.5 0.1 11.7 4.4 4.5 13.2 0.5 4.1 3.5 4.0 7.2 2.5 2.2 0.9 8.4 14.9 4.3 17.8 10.0 6.5 4.2 0.3 0.0 0.0 208.3 138.7 0.0 65.8 67.7 29.3 18.7 0.0 2.4 0.0 0.3 345.3 13.9 70.9 0.0 24.1 46.0 0.0 0.0 21.3 0.6 0.0 21.7 0.0 0.0 59.3 1.5 16.8 46.6 55.3 76.8 0.0 1.5 0.7 311.8 0.0 0.0 0.0 0.0 0.0 24.0 0.1 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 8.8 24.0 33.2 27.3 0.1 8.3 0.0 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 2.6 2.3 1.9 3.6 3.9 2.3 4.3 3.5 2.2 6.5 1.9 3.2 0.5 5.5 0.1 4.0 0.1 1.3 0.6 1.8 4.2 19.0 0.5 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.5 4.5 0.5 7.7 1.2 0.0 0.0 3.6 0.2 0.8 76.1 5.6 1.1 0.0 0.0 8.6 0.5 0.7 5.0 6.7 0.0 0.0 0.0 4.7 2.1 0.0 0.8 5.4 13.1 0.0 0.5 0.0 2.0 5.0 1.1 0.0 8.2 0.6 0.2 0.0 0.1 0.0 0.7 0.0 93.0 4.8 11.6 8.4 0.7 2.4 0.8 0.4 1.2 0.0 0.2 KATNAL1 MGC2599 ENSG00000102781 "Katanin catalytic subunit A1 like 1" Q9BW62 13 30202630-30307551 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 144.3;Excitatory neurons: 80.6;Oligodendrocytes: 78.5;Spermatocytes: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 63.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046205 Uncertain Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA046205: AB_10965325" "unprognostic (3.34e-1)" "unprognostic (6.44e-3)" "unprognostic (2.08e-2)" "unprognostic (6.91e-2)" "unprognostic (2.53e-1)" "unprognostic (1.52e-1)" "unprognostic (1.57e-2)" "unprognostic (2.84e-2)" "unprognostic (3.43e-1)" "unprognostic (4.68e-3)" "unprognostic (4.54e-2)" "unprognostic (2.17e-2)" "unprognostic (1.84e-3)" "unprognostic (7.41e-2)" "unprognostic (6.42e-2)" "unprognostic (5.12e-2)" "unprognostic (1.83e-3)" 8.7 3.8 7.0 5.0 8.8 6.5 4.7 7.5 8.9 9.7 0.0 8.7 1.4 9.3 2.7 5.8 4.8 3.8 17.9 8.0 8.1 4.0 3.9 4.9 6.5 7.2 6.4 4.2 1.9 2.2 2.9 3.0 7.0 4.5 4.1 7.9 2.2 5.9 5.1 2.6 2.8 15.0 7.5 3.3 2.8 20.8 8.4 9.2 3.0 6.6 7.1 5.0 5.2 11.8 11.7 9.6 16.5 8.8 12.3 26.0 0.4 47.5 15.2 24.9 19.4 1.9 11.6 18.8 5.5 63.7 31.3 3.2 11.8 12.2 37.5 16.3 4.4 13.4 11.2 4.4 6.5 6.7 8.7 10.1 6.0 28.0 6.8 23.3 26.4 10.2 7.3 8.1 30.8 2.4 15.2 6.1 7.1 0.2 6.1 16.8 19.4 1.9 8.8 0.8 6.8 14.3 12.6 2.6 9.0 13.6 4.1 4.1 24.2 21.8 32.7 12.1 19.3 4.2 8.2 25.8 8.7 6.5 32.1 1.5 0.7 2.9 4.4 0.4 2.1 1.9 3.4 4.4 1.9 4.5 0.8 1.8 0.2 7.7 0.9 5.5 5.8 1.2 7.0 8.8 7.5 8.9 8.0 8.1 7.2 6.4 7.0 7.5 8.4 11.8 12.9 9.6 1.8 30.3 7.2 5.9 3.9 4.7 6.2 10.2 4.0 5.6 41.4 2.8 2.3 5.5 27.1 0.4 6.6 0.3 3.9 6.5 144.3 10.3 26.5 9.3 10.2 16.4 80.6 1.5 0.8 12.3 1.5 3.6 10.1 10.3 7.9 10.6 2.9 21.9 34.5 1.0 0.0 2.8 8.9 50.7 9.0 5.9 17.8 21.5 21.9 9.6 13.4 29.1 78.5 5.7 0.0 5.3 6.4 1.9 0.3 8.4 14.7 18.7 6.6 11.9 13.7 59.0 24.6 5.2 5.7 0.3 9.8 19.2 0.7 1.7 KCNMA1 "KCa1.1, mSLO1, SLO" ENSG00000156113 "Potassium calcium-activated channel subfamily M alpha 1" Q12791 10 76869601-77638369 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 138.7" "Cell type enhanced" "Detected in many" "Astrocytes: 471.1;Bipolar cells: 409.8;Excitatory neurons: 1023.7;Inhibitory neurons: 635.9;Oligodendrocyte precursor cells: 708.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4;non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 2.4" "Cell line enhanced" "Detected in many" "BJ: 100.8;hTERT-HME1: 115.3;PC-3: 159.6;U-138 MG: 112.6;U-87 MG: 109.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054648 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA054648: AB_2682556" "unprognostic (1.25e-1)" "unprognostic (2.23e-2)" "unprognostic (1.86e-2)" "unprognostic (5.29e-2)" "unprognostic (9.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" "unprognostic (2.81e-2)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" "unprognostic (4.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.26e-2)" "unprognostic (1.42e-2)" "unprognostic (5.19e-2)" "unprognostic (1.42e-2)" "unprognostic (3.99e-3)" 10.9 12.6 36.2 8.9 38.0 1.0 15.8 1.0 45.0 54.4 4.2 118.2 7.3 138.7 31.4 33.7 47.8 22.4 3.7 36.4 10.1 11.4 19.2 9.6 7.8 4.8 15.2 13.9 8.0 0.2 26.9 4.8 5.7 48.3 21.1 40.2 42.8 76.1 96.6 5.0 23.3 92.8 1.0 24.1 33.6 5.8 15.6 2.1 3.0 18.7 3.5 44.3 24.6 28.4 0.3 30.3 0.1 0.3 4.6 24.8 0.3 100.8 89.2 23.9 11.8 6.7 0.6 0.0 0.7 75.9 56.8 0.2 0.0 59.0 14.6 60.9 0.6 0.0 0.0 0.0 45.0 0.0 0.4 17.4 10.7 38.3 115.3 84.0 9.8 0.5 0.0 0.0 42.6 1.2 1.9 0.2 1.8 0.2 159.6 0.1 3.6 0.1 15.3 0.2 9.1 1.1 0.0 2.5 0.1 11.9 12.2 0.1 65.4 112.6 12.7 20.6 90.0 0.0 0.2 0.0 109.8 0.1 45.1 0.0 0.1 0.0 0.0 2.4 0.0 0.7 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.1 36.2 38.0 1.0 45.0 36.4 10.1 4.8 15.2 5.7 1.0 15.6 28.4 0.9 0.0 4.3 471.1 2.8 2.0 71.7 5.7 17.6 409.8 30.4 43.9 3.5 5.7 4.8 1.8 60.5 0.3 0.5 2.8 29.4 3.3 74.4 20.9 17.9 3.4 4.9 0.0 1023.7 10.7 0.2 16.2 0.5 29.7 0.0 1.9 2.5 27.3 10.8 6.7 635.9 59.6 46.8 106.0 3.9 63.1 3.7 36.7 48.0 133.0 4.0 52.3 0.0 708.2 33.9 8.7 1.4 1.2 8.7 64.0 1.4 0.9 0.1 17.2 6.6 20.6 19.2 3.4 2.5 7.7 0.3 0.3 0.7 177.2 1.7 2.4 KCNQ5 Kv7.5 ENSG00000185760 "Potassium voltage-gated channel subfamily Q member 5" Q9NR82 6 72621792-73198853 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 28.3;skeletal muscle: 21.1;tongue: 12.2" "Group enriched" "Detected in some" 30 "Excitatory neurons: 2136.7;Inhibitory neurons: 862.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 28.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 34.9;HEL: 23.2;HL-60: 31.5;U-251 MG: 23.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016655 Approved Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA016655: AB_1855557" "unprognostic (4.91e-2)" "unprognostic (1.42e-1)" "unprognostic (4.96e-2)" "unprognostic (3.78e-2)" "unprognostic (2.69e-1)" "unprognostic (2.18e-2)" "unprognostic (3.57e-2)" "unprognostic (1.43e-1)" "unprognostic (6.09e-2)" "unprognostic (8.55e-2)" "unprognostic (7.96e-2)" "unprognostic (1.05e-1)" "unprognostic (6.77e-2)" "unprognostic (1.08e-2)" "unprognostic (2.62e-1)" "unprognostic (8.16e-2)" "unprognostic (1.39e-3)" 0.1 1.6 1.2 1.3 7.5 5.1 0.4 0.0 28.3 0.4 0.0 0.4 0.2 0.1 0.0 0.9 0.3 0.3 0.2 4.3 0.0 0.1 0.2 0.3 2.2 17.4 1.0 0.1 0.1 0.0 0.2 0.4 19.4 1.3 0.3 0.2 1.2 0.9 21.1 0.1 0.7 0.3 0.0 1.1 0.3 1.2 0.0 1.7 4.7 12.2 2.0 0.9 0.6 4.6 4.4 1.1 0.0 0.2 0.0 1.5 0.0 34.9 5.2 5.1 4.3 0.0 0.0 21.2 0.0 11.9 0.4 0.7 0.1 2.1 6.1 0.3 7.2 23.2 0.1 0.0 0.9 31.5 0.0 0.3 0.8 14.5 14.9 3.3 0.0 0.0 1.4 14.2 10.2 0.1 0.0 13.5 1.3 0.0 7.1 0.0 1.1 14.4 1.9 0.0 5.8 2.7 0.0 0.1 13.7 0.2 4.3 2.3 0.0 21.0 9.2 0.1 23.4 14.8 0.4 9.3 0.2 14.9 1.2 0.3 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.4 0.1 0.3 0.3 0.3 0.0 0.6 0.0 0.0 0.0 0.0 1.2 7.5 0.0 28.3 4.3 0.0 17.4 1.0 19.4 0.0 0.0 4.6 0.0 0.0 0.0 38.8 7.6 0.3 3.6 0.7 5.2 0.3 0.4 0.5 3.6 0.0 0.1 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 5.5 2136.7 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 862.4 0.0 0.0 0.0 1.5 1.6 0.0 0.2 1.8 49.6 0.0 0.1 1.0 30.2 26.7 0.0 0.0 0.0 7.6 5.7 0.0 0.0 0.0 0.2 0.0 6.0 0.8 0.5 0.5 0.8 0.3 0.3 2.8 0.0 0.0 0.7 KDELR3 ENSG00000100196 "KDEL endoplasmic reticulum protein retention receptor 3" O43731 22 38468078-38483447 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 73.2;Fibroblasts: 54.7;Intestinal goblet cells: 70.6;Proximal enterocytes: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 267.0;BJ: 180.5;BJ hTERT+: 182.0;fHDF/TERT166: 289.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043477, HPA076405" Uncertain Supported "Endoplasmic reticulum" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA043477: AB_10962952, HPA076405: AB_2686797" "unprognostic (1.76e-1)" "unprognostic (3.77e-2)" "unprognostic (1.81e-1)" "unprognostic (1.20e-2)" "unprognostic (2.90e-1)" "unprognostic (2.05e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (2.26e-1)" "unprognostic (1.91e-1)" "unprognostic (1.23e-1)" "unprognostic (9.25e-3)" "unprognostic (2.45e-1)" "prognostic unfavorable (6.05e-10)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (8.24e-2)" "unprognostic (2.07e-2)" 13.4 4.4 0.9 7.6 1.3 2.0 12.2 2.9 2.1 31.1 8.7 18.1 15.4 7.5 29.5 4.8 7.4 19.6 15.7 1.3 0.9 8.5 12.6 10.3 3.2 1.5 1.7 3.5 15.9 12.1 14.2 16.0 1.1 19.7 22.5 3.1 34.4 10.9 2.1 4.1 18.5 15.5 1.3 2.5 35.0 3.9 1.1 1.7 6.3 3.7 7.2 12.5 4.4 1.5 35.8 11.1 8.7 37.2 142.7 267.0 6.4 180.5 182.0 42.7 105.3 22.1 45.1 0.3 38.2 289.3 15.2 5.1 8.9 10.7 51.0 0.4 21.8 2.5 8.7 55.2 62.9 0.4 24.1 99.9 8.0 53.9 5.7 60.1 52.4 0.3 9.0 0.1 70.7 56.8 0.1 1.3 2.1 150.2 33.2 0.2 2.4 11.8 51.5 4.8 0.7 4.6 46.7 2.7 22.9 3.6 13.3 2.4 41.5 45.8 29.0 160.3 18.0 1.7 0.6 0.2 73.5 0.1 65.0 0.0 0.0 0.0 0.2 0.0 0.8 0.3 0.2 0.1 0.0 0.1 0.2 0.2 0.2 0.0 0.0 1.6 0.2 0.1 0.9 1.3 2.9 2.1 1.3 0.9 1.5 1.7 1.1 1.3 1.1 1.5 14.5 0.0 4.8 0.3 4.5 7.6 5.7 7.5 1.2 1.3 10.0 4.2 2.5 8.6 10.0 14.7 2.1 5.1 0.3 9.1 7.9 19.0 0.2 8.0 19.4 10.2 4.9 0.8 0.7 31.6 73.2 54.7 24.5 11.0 1.3 6.9 14.6 5.3 4.7 0.0 0.5 70.6 0.0 0.9 14.5 0.6 32.6 1.1 16.0 1.9 1.0 6.3 0.0 0.0 0.4 31.5 4.9 16.1 12.8 16.3 40.1 0.8 9.2 1.4 0.0 1.7 20.5 0.5 2.4 1.6 7.1 8.2 2.3 4.2 11.1 7.8 KIRREL3 "KIAA1867, KIRRE, NEPH2" ENSG00000149571 "Kirre like nephrin family adhesion molecule 3" Q8IZU9 11 126423358-127003460 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 21.5" "Group enriched" "Detected in some" 16 "Excitatory neurons: 274.4;Inhibitory neurons: 482.6;Oligodendrocytes: 390.3" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 8.3" "Lineage enriched" "Detected in single" 12 "dendritic cells: 8.3" "Cell line enhanced" "Detected in some" "BJ: 25.2;BJ hTERT+: 14.7;BJ hTERT+ SV40 Large T+: 9.3;BJ hTERT+ SV40 Large T+ RasG12V: 9.7;fHDF/TERT166: 18.3;U-138 MG: 11.3;U-251 MG: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053324 Enhanced "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA053324: " "unprognostic (1.92e-1)" "unprognostic (5.29e-2)" "unprognostic (1.06e-1)" "unprognostic (4.72e-2)" "unprognostic (2.50e-2)" "unprognostic (1.09e-1)" "unprognostic (4.49e-3)" "unprognostic (6.23e-3)" "unprognostic (4.08e-2)" "unprognostic (1.76e-1)" "unprognostic (7.05e-3)" "unprognostic (3.81e-2)" "unprognostic (4.06e-6)" "unprognostic (9.91e-3)" "unprognostic (1.15e-1)" "unprognostic (2.76e-2)" "unprognostic (2.92e-1)" 0.2 1.4 17.3 0.5 21.5 0.3 0.1 4.9 19.9 0.6 0.0 3.8 0.4 0.1 0.0 0.4 0.1 0.2 2.1 15.5 8.5 0.2 0.1 0.0 0.6 12.2 14.6 0.5 0.2 0.0 0.1 0.3 7.6 0.3 0.4 2.5 1.4 1.1 0.0 0.1 0.8 0.5 14.0 2.5 0.6 0.2 16.0 0.0 0.1 0.2 0.4 0.6 0.3 17.8 0.4 3.0 0.2 0.0 0.0 0.1 0.2 25.2 14.7 9.3 9.7 0.0 0.1 0.0 0.1 18.3 0.1 0.1 0.0 0.0 5.7 0.1 0.0 0.1 0.4 0.0 0.0 0.3 0.7 0.0 0.0 1.8 0.0 4.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 6.1 0.2 0.4 0.5 0.0 0.0 1.3 0.0 0.1 2.8 0.2 0.1 0.2 0.0 0.0 0.1 0.4 0.0 11.3 7.8 4.5 14.1 0.0 0.0 0.0 0.1 0.0 5.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.3 0.0 0.0 17.3 21.5 4.9 19.9 15.5 8.5 12.2 14.6 7.6 14.0 16.0 17.8 0.0 0.0 0.0 9.1 0.0 0.0 0.1 0.2 0.0 17.3 0.1 0.1 2.2 1.5 0.4 0.0 0.0 0.0 5.4 0.9 0.0 0.1 5.2 0.0 0.1 0.2 0.0 0.0 274.4 0.0 0.0 0.5 0.0 0.1 1.3 0.3 0.4 0.0 0.0 0.0 482.6 0.4 2.0 0.0 0.3 12.9 0.0 0.2 1.8 18.7 0.1 0.5 0.0 23.1 390.3 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.2 0.3 0.1 0.3 0.0 0.1 0.0 0.2 0.2 0.2 0.1 KISS1 ENSG00000170498 "KiSS-1 metastasis suppressor" Q15726 1 204190341-204196491 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "placenta: 233.1" "Cell type enriched" "Detected in many" 26 "Syncytiotrophoblasts: 1336.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.2" "Region enriched" "Detected in some" 6 "hypothalamus: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "BJ: 145.5;U-2 OS: 59.4" "Not detected" "Not detected" "CAB017775, HPA035542" Enhanced Approved Vesicles "Secreted in female reproductive system" NA NA 860000 "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "CAB017775: , HPA035542: AB_2674677" "unprognostic (9.64e-2)" "unprognostic (1.78e-2)" "unprognostic (1.86e-2)" "unprognostic (1.18e-2)" "unprognostic (3.89e-1)" "unprognostic (6.87e-2)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (1.63e-1)" "unprognostic (8.98e-12)" "unprognostic (2.25e-1)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "prognostic favorable (6.29e-6)" 0.0 0.0 0.4 0.0 0.8 0.0 0.1 0.6 0.6 0.3 0.8 0.2 0.9 0.2 0.0 0.1 0.1 0.0 0.1 0.4 10.7 2.4 4.3 1.3 0.0 1.8 0.3 0.0 1.0 0.0 3.1 233.1 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.1 1.3 0.2 0.2 2.0 3.2 5.2 1.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.4 145.5 1.8 2.5 0.7 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.9 0.2 0.0 0.2 0.1 0.0 0.0 0.9 0.2 0.1 0.0 0.7 0.0 0.8 0.2 0.3 0.0 0.1 59.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.6 0.6 0.4 10.7 1.8 0.3 0.4 0.2 1.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 4.0 7.5 0.0 1.0 1.2 0.6 0.0 1.5 2.2 0.0 0.0 9.3 0.0 1.5 0.0 11.3 40.2 0.2 0.0 1.4 0.0 0.0 0.1 4.9 6.9 1.9 4.1 0.5 0.0 0.4 0.7 2.8 15.1 0.0 0.0 0.6 0.0 0.0 0.0 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.5 0.0 0.1 50.1 17.0 1.4 0.4 0.0 0.0 0.0 7.1 0.6 1.1 0.0 0.0 1336.6 0.1 0.1 2.1 14.3 KLC1 "hKLC1B, hKLC1G, hKLC1J, hKLC1N, hKLC1P, hKLC1R, hKLC1S, KLC, KNS2, KNS2A" ENSG00000126214 "Kinesin light chain 1" Q07866 14 103561896-103714249 "Predicted intracellular proteins" "Host-virus interaction" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 397.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009798, HPA044617, HPA052450" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 14000 "Cluster 26: Non-specific - Mitochondria" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009798: AB_2280879, HPA044617: AB_2679024, HPA052450: AB_2681838" "unprognostic (6.93e-3)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (7.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.19e-1)" "unprognostic (1.21e-3)" "unprognostic (2.67e-2)" "unprognostic (9.21e-2)" "unprognostic (5.62e-2)" "prognostic favorable (6.75e-4)" "unprognostic (6.84e-3)" "prognostic unfavorable (7.17e-4)" "unprognostic (6.58e-2)" "unprognostic (8.69e-2)" "unprognostic (4.05e-1)" "unprognostic (1.49e-1)" 70.8 49.4 282.9 42.2 302.0 50.3 63.0 273.5 358.7 74.8 220.4 89.9 26.2 71.5 43.9 66.0 65.0 38.4 100.0 310.6 299.8 35.6 29.9 66.0 44.2 378.9 305.0 62.8 43.0 48.5 86.7 45.9 397.0 47.1 34.3 158.6 54.2 47.1 123.4 68.2 48.7 58.0 300.0 49.0 53.9 45.6 301.7 40.2 48.6 71.5 47.4 66.5 69.8 304.0 57.0 74.2 138.6 76.3 92.6 102.8 65.5 129.5 105.4 118.6 81.7 64.0 60.8 75.8 65.2 139.3 53.2 93.0 85.8 69.6 112.0 89.9 43.9 41.6 92.8 66.1 106.8 83.4 79.5 73.4 109.3 89.6 112.1 126.5 104.2 52.8 63.5 83.7 104.4 94.6 56.9 74.0 45.6 90.1 140.4 53.0 60.6 38.2 74.7 122.5 165.1 93.5 105.7 52.7 90.2 85.9 47.9 40.1 152.7 88.4 43.5 123.1 74.1 65.9 50.0 83.3 101.7 47.7 97.0 5.5 4.6 9.8 7.3 4.6 6.6 5.0 6.5 7.8 5.1 6.8 5.7 5.0 5.0 3.1 6.5 7.6 7.0 2.9 282.9 302.0 273.5 358.7 310.6 299.8 378.9 305.0 397.0 300.0 301.7 304.0 45.2 44.8 32.6 92.4 24.3 26.0 45.1 30.1 13.6 140.8 18.7 19.7 39.3 15.7 21.5 20.2 52.1 22.6 29.5 17.9 9.8 42.9 8.0 30.8 41.8 45.5 44.9 13.2 84.1 30.7 30.6 37.4 27.0 43.2 33.6 31.5 39.3 18.9 30.5 138.0 80.8 24.3 28.5 19.9 23.8 17.0 38.5 24.4 39.2 73.1 36.3 45.4 20.6 57.3 89.8 71.2 17.3 48.2 26.2 46.6 15.8 5.1 23.8 106.1 26.3 46.4 46.8 64.8 83.3 20.1 17.6 42.1 30.8 17.1 17.5 38.4 KLF17 "FLJ40160, Zfp393, ZNF393" ENSG00000171872 "Kruppel like factor 17" Q5JT82 1 44118821-44135140 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 8.3" "Cell type enhanced" "Detected in some" "Early spermatids: 160.6;Late spermatids: 45.3;Oligodendrocyte precursor cells: 29.1" "Cancer enriched" "Detected in single" 25 "testis cancer: 4.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 1.5;BJ hTERT+ SV40 Large T+ RasG12V: 1.2;HBF TERT88: 1.5;U-138 MG: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA024629 Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "HPA024629: AB_1668927" "unprognostic (1.73e-2)" "unprognostic (1.18e-4)" "unprognostic (4.02e-4)" "unprognostic (2.38e-1)" "unprognostic (4.64e-2)" "unprognostic (5.17e-2)" "unprognostic (1.58e-2)" "unprognostic (1.88e-1)" "unprognostic (9.70e-3)" "unprognostic (5.30e-3)" "unprognostic (8.35e-2)" "unprognostic (5.54e-2)" "unprognostic (6.60e-2)" "unprognostic (8.04e-3)" 0.0 0.6 0.1 0.2 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.4 0.0 0.7 0.1 0.5 0.3 0.2 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 1.1 0.1 0.0 0.1 8.3 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 1.5 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 2.6 0.3 0.1 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 160.6 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 45.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 29.1 4.9 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 1.3 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 KRT33B "Ha-3II, KRTHA3B" ENSG00000131738 "Keratin 33B" Q14525 17 41363498-41369813 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "skin 1: 82.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 2.9;Ionocytes: 2.0" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "BJ: 4.3;BJ hTERT+ SV40 Large T+ RasG12V: 1.1" HPA055194 Supported NA NA 350000000 "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA055194: AB_2682733" "unprognostic (3.34e-2)" "unprognostic (5.19e-2)" "unprognostic (3.04e-1)" "unprognostic (1.55e-2)" "unprognostic (6.28e-2)" 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 82.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 KRT34 "Ha-4, KRTHA4" ENSG00000131737 "Keratin 34" O76011 17 41377650-41382403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skin 1: 66.6" "Group enriched" "Detected in some" 8 "Early spermatids: 5.4;Late spermatids: 15.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "BJ: 201.8" "Not detected" "Not detected" "HPA055194, HPA072208" Enhanced Approved Nucleoplasm,Vesicles NA NA 170000000 "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA055194: AB_2682733, HPA072208: AB_2686494" "unprognostic (2.52e-1)" "unprognostic (2.14e-1)" "unprognostic (9.03e-2)" "unprognostic (2.94e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.86e-3)" "unprognostic (5.12e-7)" "unprognostic (3.84e-2)" 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 66.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 1.1 1.8 0.0 1.6 0.0 0.0 0.0 0.1 1.9 0.0 201.8 8.8 23.5 46.4 0.0 0.1 0.0 0.0 25.1 0.1 0.0 0.0 0.0 42.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 8.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 6.1 26.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.3 0.1 0.0 0.3 0.0 0.0 KRTAP1-5 KAP1.5 ENSG00000221852 "Keratin associated protein 1-5" Q9BYS1 17 41026026-41027208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "skin 1: 79.0" "Group enriched" "Detected in some" 8 "Basal prostatic cells: 4.1;Syncytiotrophoblasts: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 3.9;BJ: 17.1;fHDF/TERT166: 10.6;HDLM-2: 6.5;U-138 MG: 4.6;U-87 MG: 3.4" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (1.76e-1)" "unprognostic (2.96e-2)" "unprognostic (2.24e-2)" "unprognostic (2.55e-1)" "unprognostic (1.90e-1)" "unprognostic (9.98e-2)" "unprognostic (1.80e-2)" "unprognostic (5.60e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 79.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.7 0.0 0.1 0.0 0.2 KRTAP2-3 KAP2.3 ENSG00000212724 "Keratin associated protein 2-3" P0C7H8 17 41059240-41060114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 104 "skin 1: 20.6" "Cell type enhanced" "Detected in some" "Ductal cells: 104.8;Endometrial ciliated cells: 22.0;Glandular and luminal cells: 35.5;Pancreatic endocrine cells: 10.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 36.8;fHDF/TERT166: 22.2;HBF TERT88: 31.9;LHCN-M2: 41.0;U-2 OS: 15.9" HPA059203 Supported NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "HPA059203: AB_2683947" "unprognostic (2.22e-1)" "unprognostic (2.58e-2)" "unprognostic (3.79e-3)" "unprognostic (3.25e-3)" "unprognostic (2.78e-2)" "unprognostic (6.91e-2)" "unprognostic (1.38e-1)" "unprognostic (6.41e-4)" "unprognostic (7.83e-6)" "unprognostic (1.71e-1)" "unprognostic (9.36e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.1 0.0 36.8 1.2 9.0 7.6 0.4 0.3 0.0 0.0 22.2 2.2 0.1 0.0 0.6 31.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.3 0.5 0.6 0.0 0.0 0.0 0.0 41.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.2 0.0 5.4 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 15.9 1.0 1.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.5 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 104.8 0.0 22.0 1.6 0.4 0.0 0.0 0.0 0.6 0.4 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 LAMB2 "LAMS, NPHS5" ENSG00000172037 "Laminin subunit beta 2" P55268 3 49121114-49133118 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 151.8;Leydig cells: 146.3;Peritubular cells: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 299.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000053, HPA001895, HPA050033, CAB078160" Supported Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 25000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "CAB000053: AB_2313665, CAB078160: AB_2665799, HPA001895: AB_1079227, HPA050033: " "unprognostic (1.12e-2)" "unprognostic (4.40e-2)" "unprognostic (5.14e-3)" "unprognostic (1.10e-1)" "unprognostic (4.08e-1)" "unprognostic (4.01e-1)" "unprognostic (5.59e-2)" "unprognostic (6.80e-2)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (1.26e-1)" "unprognostic (4.96e-2)" "unprognostic (1.21e-3)" "unprognostic (1.78e-1)" "unprognostic (4.38e-2)" "unprognostic (6.20e-2)" "unprognostic (1.24e-2)" 75.2 73.2 12.8 18.2 14.2 2.6 58.2 15.1 14.9 68.0 47.7 63.1 24.6 72.7 25.5 31.9 63.8 62.2 169.1 13.1 14.5 41.3 31.7 55.1 16.9 20.0 14.8 94.4 32.7 104.7 15.4 99.0 15.4 50.4 18.0 11.7 40.3 81.0 67.5 40.9 32.5 80.2 14.1 29.8 48.4 21.4 17.3 6.7 60.2 70.0 12.8 52.2 55.9 13.5 15.7 38.7 34.4 122.0 196.3 201.5 31.1 131.9 161.8 73.8 75.7 18.3 52.0 0.2 44.4 299.0 38.3 49.3 30.0 47.6 52.3 0.1 9.5 6.9 63.4 32.1 132.5 0.3 0.3 176.9 69.4 61.6 62.1 184.3 75.9 0.0 4.1 0.1 61.4 30.3 0.1 0.3 15.1 20.7 32.0 0.2 16.6 0.5 53.5 19.1 0.2 20.4 74.9 42.9 68.3 57.5 93.4 0.9 126.9 82.2 34.9 28.5 35.4 0.1 0.4 0.4 39.1 0.3 57.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 14.2 15.1 14.9 13.1 14.5 20.0 14.8 15.4 14.1 17.3 13.5 83.7 118.6 53.5 26.1 2.4 31.2 13.9 33.6 33.0 1.7 39.4 40.5 151.8 37.1 43.6 55.2 6.2 11.3 0.9 3.6 5.9 26.4 3.5 15.4 24.4 77.8 0.0 0.4 0.2 9.4 6.4 120.1 50.4 27.2 1.3 88.9 94.9 49.9 10.4 8.4 0.4 3.1 32.6 10.1 31.1 12.3 146.3 7.5 42.7 15.9 3.5 46.7 2.1 1.0 0.6 14.1 14.9 140.7 0.5 10.2 16.4 28.6 11.2 2.6 118.3 80.8 92.3 4.3 8.6 14.2 24.4 9.4 3.8 27.6 5.6 9.3 LASP1 "Lasp-1, MLN50" ENSG00000002834 "LIM and SH3 protein 1" Q14847 17 38869859-38921770 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 591.7;Proximal enterocytes: 292.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012072, CAB022049" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 9400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Focal adhesion sites" "CAB022049: , HPA012072: AB_1852714" "unprognostic (1.23e-1)" "unprognostic (2.09e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.47e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-1)" "unprognostic (9.60e-2)" "unprognostic (9.87e-3)" "unprognostic (1.01e-1)" "unprognostic (9.65e-3)" "unprognostic (1.29e-3)" "unprognostic (3.95e-2)" "unprognostic (1.60e-3)" "unprognostic (4.53e-2)" 86.4 38.0 60.8 75.9 56.7 126.4 55.5 45.5 56.7 46.9 48.6 93.0 131.9 43.8 32.3 45.9 46.0 56.8 40.3 56.1 61.0 55.9 76.4 68.6 76.1 56.2 63.5 48.5 59.0 25.5 33.0 81.4 59.0 30.9 92.3 26.8 44.8 33.9 23.7 44.4 168.8 51.2 52.9 74.3 96.2 23.9 67.4 74.1 34.9 27.7 78.2 53.2 37.3 50.1 214.1 441.0 124.1 111.0 182.8 196.9 218.7 267.8 257.8 274.5 198.5 134.3 225.8 98.8 214.1 417.3 154.9 332.4 58.5 204.1 239.6 71.6 31.6 47.5 124.2 235.8 173.0 110.4 134.1 176.3 69.6 234.6 66.1 170.7 188.0 59.0 81.9 30.3 389.4 72.0 127.1 163.6 63.0 189.9 109.4 70.7 67.6 123.8 332.7 187.9 19.0 45.4 159.3 160.5 134.7 233.5 255.7 128.2 331.4 160.0 233.0 189.7 162.0 79.7 115.8 75.2 170.2 96.7 197.2 21.8 31.4 35.0 30.7 33.1 20.3 11.7 15.2 20.4 27.3 10.8 12.7 19.8 67.0 34.2 42.1 20.5 21.4 32.5 60.8 56.7 45.5 56.7 56.1 61.0 56.2 63.5 59.0 52.9 67.4 50.1 54.5 41.7 27.6 17.6 41.8 41.8 21.5 26.0 51.8 66.4 82.4 43.2 1.1 55.8 30.4 73.5 10.4 7.5 69.5 225.2 17.6 65.7 89.6 27.5 31.7 54.3 86.5 21.0 16.4 76.5 59.1 50.1 119.3 46.4 52.0 37.4 64.6 115.4 83.9 26.9 16.0 101.9 28.5 127.7 73.0 591.7 51.9 71.9 35.6 24.4 94.3 22.2 164.8 11.1 4.4 111.0 116.4 39.9 32.8 24.2 292.7 72.9 57.3 23.1 65.7 65.4 53.4 2.9 5.7 62.2 28.4 6.4 63.4 19.2 97.8 31.8 LAYN "FLJ30977, FLJ31092" ENSG00000204381 Layilin Q6UX15 11 111540280-111561745 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Prostatic glandular cells: 233.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "myeloid DC: 11.2;T-reg: 13.4" "Group enriched" "Detected in many" 123 "dendritic cells: 11.2;T-cells: 13.4" "Cell line enhanced" "Detected in many" "BJ: 150.7;BJ hTERT+: 153.7;BJ hTERT+ SV40 Large T+ RasG12V: 96.7;fHDF/TERT166: 95.1;HSkMC: 88.8;hTERT-RPE1: 94.0;U-138 MG: 108.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040087 Approved Approved Cytosol NA NA 340000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA040087: AB_10793927" "unprognostic (2.27e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-3)" "unprognostic (1.96e-1)" "unprognostic (3.90e-2)" "unprognostic (1.83e-2)" "unprognostic (5.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.38e-1)" "unprognostic (7.75e-3)" "unprognostic (4.47e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-2)" "unprognostic (5.01e-2)" "unprognostic (1.65e-1)" "unprognostic (2.91e-2)" "unprognostic (1.35e-2)" 10.7 2.0 15.6 5.7 21.4 1.0 8.5 15.7 19.6 15.6 13.7 29.2 3.8 15.8 10.1 4.7 17.7 17.0 7.0 16.6 17.1 5.7 0.9 11.3 7.1 17.4 19.7 39.1 2.0 6.4 6.2 14.1 16.3 14.6 3.3 0.8 5.5 17.0 6.1 2.6 10.6 22.5 14.2 8.2 13.1 4.4 18.0 10.3 27.4 6.1 5.0 8.8 12.2 23.7 0.4 3.9 0.8 0.0 25.4 48.0 7.6 150.7 153.7 71.0 96.7 0.2 0.1 0.0 1.4 95.1 18.7 3.2 9.9 0.7 74.2 0.2 0.5 0.8 0.0 0.2 41.7 0.0 0.2 88.8 0.0 30.8 0.2 94.0 0.9 0.0 0.0 0.1 29.4 0.0 0.1 0.1 4.8 0.0 0.0 0.0 11.4 0.2 0.6 0.0 4.9 18.9 0.5 0.2 0.4 34.9 0.1 0.7 0.6 108.8 81.2 1.0 74.3 0.0 0.0 0.2 14.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 11.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 13.4 0.4 15.6 21.4 15.7 19.6 16.6 17.1 17.4 19.7 16.3 14.2 18.0 23.7 22.2 19.2 2.8 0.3 0.3 2.2 48.8 44.8 0.6 0.4 0.7 15.0 2.7 2.8 23.3 0.0 0.0 1.6 2.6 0.0 0.0 6.5 2.5 3.9 7.7 50.9 0.0 2.7 0.3 0.2 2.1 13.1 0.0 0.9 1.3 9.6 6.8 0.1 0.7 0.0 1.4 0.0 6.1 0.6 13.6 1.8 22.7 1.2 0.0 2.8 0.6 0.2 0.0 4.0 30.1 0.8 0.0 55.3 2.8 233.0 0.0 0.2 32.0 0.2 32.9 2.6 17.3 0.1 2.3 0.1 2.3 0.5 14.5 11.2 0.0 50.3 LBH ENSG00000213626 "LBH regulator of WNT signaling pathway" Q53QV2 2 30231534-30323730 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 210.6;Pancreatic endocrine cells: 298.9;Smooth muscle cells: 435.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 112.4;MAIT T-cell: 110.2;memory B-cell: 92.0;memory CD4 T-cell: 83.8;memory CD8 T-cell: 86.1;naive B-cell: 123.0;naive CD4 T-cell: 140.2;naive CD8 T-cell: 124.6;T-reg: 89.2" "Group enriched" "Detected in all" 7 "B-cells: 123.0;T-cells: 140.2" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 302.4;hTERT-RPE1: 150.6;U-2 OS: 95.1" "Low region specificity" "Detected in all" HPA034669 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA034669: AB_10600820" "unprognostic (2.13e-2)" "unprognostic (2.34e-2)" "unprognostic (1.78e-1)" "unprognostic (4.77e-3)" "unprognostic (1.23e-3)" "unprognostic (1.57e-1)" "unprognostic (2.69e-1)" "unprognostic (3.65e-3)" "unprognostic (1.93e-1)" "unprognostic (3.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.60e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.25e-2)" "unprognostic (7.91e-3)" "unprognostic (1.67e-1)" 35.2 10.3 8.4 57.4 7.9 28.6 32.0 13.7 22.4 45.6 18.4 27.4 14.4 83.0 27.0 17.0 41.7 44.9 119.3 15.2 33.9 39.3 15.0 130.7 117.8 23.0 17.4 63.3 14.4 84.8 16.7 54.5 18.4 27.3 18.1 70.8 63.9 26.3 14.3 30.3 41.2 48.2 11.2 83.5 22.8 9.8 14.4 125.7 68.9 20.4 100.9 35.5 22.7 11.8 0.1 11.4 14.0 2.5 3.6 2.2 1.1 14.5 19.1 3.8 0.6 59.4 15.2 28.6 33.3 302.4 3.8 19.5 81.1 0.8 0.6 41.3 3.4 4.6 12.2 0.2 10.9 0.4 4.0 13.0 1.1 5.0 0.3 150.6 0.7 19.0 14.6 0.2 14.2 0.2 32.3 0.4 84.6 2.6 0.6 33.1 75.4 9.7 2.6 5.0 3.9 10.0 23.7 2.3 1.0 49.7 0.1 1.2 18.9 26.8 95.1 52.0 1.8 53.8 3.3 2.7 11.9 1.8 8.4 0.7 0.7 1.1 112.4 1.2 110.2 92.0 83.8 86.1 0.8 123.0 140.2 124.6 4.0 18.9 3.2 12.1 89.2 110.4 8.4 7.9 13.7 22.4 15.2 33.9 23.0 17.4 18.4 11.2 14.4 11.8 46.9 109.0 20.0 0.7 167.3 12.4 64.5 51.7 16.5 41.2 13.0 125.0 65.1 12.8 40.8 25.8 210.6 18.3 152.2 6.0 13.7 85.4 39.4 110.5 18.0 81.8 23.8 85.9 2.2 56.9 10.8 54.7 23.4 45.2 15.8 2.3 23.6 1.2 33.2 8.4 16.4 9.3 30.5 10.0 23.1 144.5 10.5 14.3 23.2 14.0 6.7 13.1 163.7 9.5 0.7 298.9 8.7 26.7 26.3 95.3 0.7 21.7 67.8 45.4 177.5 36.3 435.6 0.7 6.6 9.1 10.7 9.3 205.3 8.8 6.3 56.8 LCE1F LEP6 ENSG00000240386 "Late cornified envelope 1F" Q5T754 1 152776372-152776728 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "skin 1: 209.8" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 18.3" "Group enriched" "Detected in some" 13 "head and neck cancer: 5.5;melanoma: 14.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ hTERT+: 6.5;hTERT-HME1: 3.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.21e-1)" "unprognostic (8.43e-2)" 0.0 0.0 0.0 0.0 0.0 0.2 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 209.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 LCE2A LEP9 ENSG00000187173 "Late cornified envelope 2A" Q5TA79 1 152698345-152699442 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 118.2" "Cell type enriched" "Detected in single" 4 "Melanocytes: 1.8" "Cancer enriched" "Detected in some" 5 "melanoma: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 5.6;SK-MEL-30: 2.0;U-2197: 1.4" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (3.45e-2)" "unprognostic (6.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 118.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.9 0.0 1.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 LCE3A LEP13 ENSG00000185962 "Late cornified envelope 3A" Q5TA76 1 152622834-152623103 "Predicted intracellular proteins" Keratinization Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 107.7" "Cell type enhanced" "Detected in some" "Early spermatids: 3.2;Late spermatids: 1.5;Skeletal myocytes: 12.4;Spermatocytes: 1.6;Spermatogonia: 2.1" "Group enriched" "Detected in some" 9 "head and neck cancer: 26.6;melanoma: 9.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.4;LHCN-M2: 1.5;U-138 MG: 1.7" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (7.47e-2)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 107.7 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LETM2 "FLJ25409, SLC55A2" ENSG00000165046 "Leucine zipper and EF-hand containing transmembrane protein 2" Q2VYF4 8 38386207-38409527 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 23.8" "Cell type enhanced" "Detected in many" "Early spermatids: 76.9;Late spermatids: 57.6;Pancreatic endocrine cells: 48.6;Spermatocytes: 54.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 21.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 21.5" "Cell line enhanced" "Detected in many" "HBEC3-KT: 25.2;hTERT-HME1: 26.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 24.0" HPA025032 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear bodies, Cytosol" "HPA025032: AB_1852808" "unprognostic (3.37e-2)" "unprognostic (2.73e-1)" "unprognostic (3.14e-1)" "unprognostic (2.05e-2)" "unprognostic (2.27e-4)" "unprognostic (3.20e-2)" "unprognostic (3.96e-2)" "unprognostic (1.43e-1)" "unprognostic (8.27e-2)" "unprognostic (3.80e-2)" "unprognostic (1.39e-1)" "unprognostic (1.35e-1)" "unprognostic (3.40e-2)" "unprognostic (4.09e-3)" "unprognostic (2.49e-1)" "unprognostic (1.16e-1)" "unprognostic (9.25e-2)" 1.2 1.0 3.4 1.1 3.6 5.3 0.7 5.7 4.9 1.6 2.9 0.7 0.8 1.4 1.1 1.1 1.4 1.2 0.8 3.2 2.8 2.3 0.7 2.0 1.3 2.3 2.9 2.1 0.7 1.6 1.3 1.8 3.1 1.1 0.8 4.2 0.4 0.8 0.2 1.1 0.5 0.6 2.0 1.6 2.7 23.8 2.6 2.4 1.0 0.3 1.4 1.9 0.6 4.2 21.2 4.5 3.0 2.9 2.3 7.0 2.5 7.5 9.2 10.6 6.2 1.5 8.3 2.8 16.5 1.5 3.1 2.2 5.9 25.2 11.7 1.2 2.9 3.2 2.3 4.2 2.7 0.7 2.8 1.7 7.2 11.7 26.9 5.9 10.7 3.4 2.6 3.9 9.3 4.2 7.5 1.8 0.8 1.6 18.2 2.9 4.8 1.6 16.8 1.1 2.4 2.3 2.5 0.4 0.9 1.8 2.4 1.2 20.0 3.3 22.5 7.4 1.7 2.6 1.6 2.0 5.6 3.3 2.5 1.3 4.1 0.7 0.9 1.6 2.0 1.5 0.9 1.5 1.7 1.8 1.7 1.7 21.5 1.4 5.0 0.7 5.2 1.3 3.4 3.6 5.7 4.9 3.2 2.8 2.3 2.9 3.1 2.0 2.6 4.2 3.0 3.2 6.4 2.3 10.3 0.5 13.9 7.6 6.8 6.6 2.1 3.3 1.8 4.3 3.2 5.5 6.2 2.6 10.1 1.4 1.9 4.0 76.9 21.8 7.1 4.2 0.0 0.8 3.6 20.5 7.9 5.0 16.8 20.5 9.5 1.1 1.4 0.0 1.4 6.7 7.3 1.9 2.0 2.2 2.3 57.6 2.1 3.6 1.8 1.0 2.0 3.6 1.0 1.5 1.6 48.6 0.1 1.5 4.5 2.9 0.3 3.0 4.9 8.4 0.0 4.5 3.3 54.8 3.3 2.5 0.9 8.1 9.1 1.5 1.3 4.5 LGALS1 GBP ENSG00000100097 "Galectin 1" P09382 22 37675636-37679802 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3949.7;Langerhans cells: 4906.5;monocytes: 7118.4;Smooth muscle cells: 4703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 1649.6" "HPA000646, HPA000687, HPA001130, CAB002157" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" No Yes 10000000 20000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB002157: AB_563734, HPA000646: AB_1078935, HPA000687: AB_2756309, HPA001130: AB_2756311" "unprognostic (1.65e-1)" "unprognostic (8.13e-2)" "unprognostic (5.13e-2)" "prognostic favorable (2.36e-5)" "unprognostic (6.38e-2)" "unprognostic (2.67e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.22e-3)" "unprognostic (4.91e-3)" "unprognostic (2.51e-1)" "unprognostic (6.16e-3)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.18e-10)" "unprognostic (2.24e-2)" "unprognostic (8.13e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (5.10e-4)" 1921.2 778.5 482.4 523.8 520.7 324.7 1490.9 613.5 695.3 1805.7 465.2 1634.7 197.7 2270.1 196.8 387.4 1147.0 556.0 1397.4 457.7 549.0 362.4 277.4 920.2 176.7 694.5 576.1 1440.2 155.5 188.1 254.8 426.1 661.5 903.0 207.2 39.5 397.5 756.3 1172.9 472.8 475.3 1353.4 593.8 460.7 582.7 244.9 624.9 153.9 290.9 691.9 116.9 1059.7 1156.4 782.4 2850.9 1664.3 36.5 1440.9 3314.6 6505.1 32.7 6450.7 7619.4 4761.9 4716.9 189.6 368.3 3.3 649.1 6661.4 1609.2 296.3 58.8 4309.2 1663.3 2917.2 30.9 251.3 1606.3 791.1 2155.3 145.1 3167.7 4031.7 294.2 3785.7 1609.9 4271.1 5325.7 1.7 186.6 1163.4 3771.1 1287.6 5.2 2038.4 14.3 629.6 3914.9 5.4 2388.6 799.7 2000.0 6.4 5.5 843.4 1287.4 224.3 1644.5 66.7 1187.2 1689.0 7122.0 6224.0 3070.2 2788.9 3349.3 701.8 530.6 13.6 7291.9 762.0 2535.9 1086.5 3047.4 110.2 766.5 2320.4 113.6 567.7 694.9 754.2 3653.1 287.5 114.3 478.1 122.2 415.4 2556.7 899.2 1514.7 4667.0 482.4 520.7 613.5 695.3 457.7 549.0 694.5 576.1 661.5 593.8 624.9 782.4 1505.8 166.7 90.4 12.7 294.3 730.3 144.0 2796.6 49.5 10.0 144.2 477.9 986.3 74.4 213.4 163.7 6.2 88.0 466.5 49.9 17.6 690.2 30.9 183.0 3011.6 1063.6 3.0 74.9 7.5 90.4 1573.3 2540.4 28.1 230.3 540.0 172.2 653.2 614.1 3949.7 8.4 5.4 8.4 339.7 2159.0 4906.5 106.4 975.5 1700.0 2856.6 15.9 7118.4 278.0 588.1 4.0 17.1 233.5 6.1 1300.7 590.9 118.8 0.5 28.7 109.8 45.4 1650.1 1873.6 4703.8 33.8 13.1 18.2 588.0 151.5 767.5 197.2 11.6 57.0 LHX9 ENSG00000143355 "LIM homeobox 9" Q9NQ69 1 197911902-197935478 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.2;ovary: 9.2" "Group enriched" "Detected in some" 6 "Leydig cells: 157.5;Peritubular cells: 50.4" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 17.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "fHDF/TERT166: 272.7" "Group enriched" "Detected in many" 4 "hippocampal formation: 6.3;midbrain: 17.3;thalamus: 12.2" "Group enriched" "Detected in many" 5 "midbrain: 16.8;pons: 6.7;thalamus: 14.5" HPA009695 Uncertain Approved Nucleoplasm NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA009695: AB_1079251" "unprognostic (8.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.38e-4)" "unprognostic (1.43e-1)" "unprognostic (5.68e-3)" "unprognostic (3.55e-1)" "unprognostic (1.12e-2)" "unprognostic (5.52e-2)" "unprognostic (2.63e-2)" "unprognostic (3.26e-2)" "unprognostic (5.15e-2)" "unprognostic (2.62e-3)" "unprognostic (6.35e-3)" "unprognostic (1.42e-1)" "unprognostic (1.88e-1)" 0.1 0.0 2.5 0.0 0.4 0.0 0.0 0.6 0.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 4.1 0.0 0.4 1.4 0.0 1.8 17.2 9.2 0.0 0.0 0.0 0.0 2.5 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.2 15.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 27.4 4.3 7.2 0.6 0.0 0.0 0.0 0.1 272.7 0.1 0.0 6.7 0.0 2.3 0.0 0.5 0.0 7.6 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 2.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.6 0.1 8.1 7.7 3.1 0.0 0.0 0.0 0.0 6.7 0.0 2.4 1.3 11.7 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.4 0.6 0.7 0.6 4.1 1.8 17.2 2.5 0.6 15.4 1.4 0.0 3.2 15.4 0.0 0.0 0.0 0.1 0.0 0.0 5.2 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.1 1.9 0.1 1.1 1.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 157.5 0.2 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 50.4 0.0 0.0 0.0 0.2 0.7 0.4 0.0 0.0 0.5 2.5 0.9 0.0 0.0 0.1 0.1 0.1 0.2 0.1 LIMA1 EPLIN ENSG00000050405 "LIM domain and actin binding 1" Q9UHB6 12 50175788-50283546 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 553.9;Basal prostatic cells: 646.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 523.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023871, HPA052645" Enhanced Enhanced "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 90000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "Focal adhesion sites, Cytosol" "HPA023871: AB_1852875, HPA052645: AB_2681898" "unprognostic (6.22e-2)" "unprognostic (9.39e-3)" "unprognostic (8.13e-2)" "unprognostic (1.42e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (1.76e-6)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (1.28e-3)" "unprognostic (6.27e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.12e-2)" "unprognostic (9.26e-3)" "unprognostic (1.46e-1)" "unprognostic (1.43e-1)" 122.2 47.1 11.9 39.9 13.6 4.2 89.4 40.3 16.4 63.3 12.3 125.6 112.1 56.8 33.2 37.1 47.9 69.3 31.9 11.7 13.1 48.7 20.7 62.5 32.6 15.4 13.8 38.6 31.1 31.0 24.0 50.6 17.3 45.7 130.5 32.2 47.2 42.2 21.9 47.3 121.8 48.6 13.3 40.8 96.8 16.2 13.1 38.1 33.3 28.3 33.8 96.7 53.2 16.3 154.3 4.5 47.2 69.7 211.9 211.0 177.7 377.2 264.4 296.9 235.8 57.7 220.2 6.8 34.1 523.4 99.7 170.8 42.8 348.7 258.1 98.1 45.1 64.2 16.2 20.5 135.3 23.2 87.5 142.2 100.8 104.6 297.8 89.0 106.2 28.3 45.6 30.3 96.9 26.5 29.0 7.1 24.3 81.0 20.5 28.7 115.2 2.4 68.7 180.3 35.2 75.4 51.5 102.7 166.6 50.0 49.0 14.1 166.7 126.5 98.0 118.4 62.1 16.5 2.0 28.0 137.6 25.3 55.6 0.2 0.2 1.5 6.6 1.1 2.6 0.2 8.2 8.1 4.9 0.6 3.3 6.0 0.1 5.9 2.7 1.2 15.3 3.0 11.9 13.6 40.3 16.4 11.7 13.1 15.4 13.8 17.3 13.3 13.1 16.3 123.2 44.8 91.2 13.4 4.8 553.9 646.1 175.4 283.4 14.6 62.2 73.0 7.3 61.5 179.1 119.5 160.6 128.1 15.5 413.7 15.6 145.6 67.1 75.7 183.9 91.8 122.8 17.5 12.9 307.6 376.9 170.9 126.9 132.6 24.7 15.9 117.8 19.8 34.4 6.7 30.1 138.0 187.2 11.7 59.3 11.7 75.5 19.3 90.7 41.2 9.9 22.7 28.8 78.9 48.4 219.0 244.5 77.5 6.9 221.6 214.8 22.3 67.8 95.4 65.7 54.9 118.0 30.8 10.4 100.0 291.5 64.0 33.3 62.4 244.3 385.1 LIMS2 "PINCH-2, PINCH2" ENSG00000072163 "LIM zinc finger domain containing 2" Q7Z4I7 2 127638381-127681786 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 510.1" "Cell type enhanced" "Detected in many" "Adipocytes: 109.4;Cardiomyocytes: 91.7;Endothelial cells: 105.1;Granulosa cells: 134.1;Hepatic stellate cells: 134.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 22.5" "Group enriched" "Detected in many" 13 "B-cells: 22.5;T-cells: 10.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 27.0;fHDF/TERT166: 31.2;HHSteC: 32.7;MOLT-4: 40.2;TIME: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058340 Enhanced Supported "Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Focal adhesion sites" "HPA058340: AB_2683683" "unprognostic (2.51e-2)" "unprognostic (1.25e-1)" "unprognostic (5.82e-3)" "unprognostic (4.51e-2)" "unprognostic (9.25e-2)" "unprognostic (3.49e-1)" "prognostic favorable (6.53e-7)" "unprognostic (3.98e-2)" "unprognostic (3.73e-1)" "unprognostic (2.29e-1)" "unprognostic (3.78e-2)" "unprognostic (8.86e-2)" "unprognostic (3.33e-1)" "unprognostic (4.60e-3)" "unprognostic (3.64e-2)" "unprognostic (1.77e-1)" "unprognostic (4.00e-2)" 104.6 21.6 29.4 17.9 27.9 0.4 93.9 24.9 32.3 104.4 25.1 510.1 15.8 261.4 16.9 42.1 139.5 25.7 266.4 25.6 24.1 72.7 46.6 114.3 12.9 28.7 27.2 29.0 14.1 6.4 15.6 27.7 29.3 132.1 15.2 0.6 27.1 98.8 33.4 32.8 95.7 81.9 24.3 121.8 123.1 12.0 32.2 13.1 51.6 26.8 5.4 220.5 85.1 24.0 0.8 1.6 0.5 0.0 4.6 1.0 0.3 19.1 27.0 20.2 18.1 4.7 0.1 0.1 10.3 31.2 1.1 0.1 0.3 0.0 4.2 0.0 0.8 0.0 11.9 3.6 32.7 0.0 0.0 0.2 0.0 7.0 0.2 10.7 12.9 15.3 0.0 0.0 10.0 0.0 40.2 1.0 1.3 0.0 2.4 9.0 1.7 1.0 1.3 0.0 0.1 0.2 3.0 1.7 0.7 6.7 0.7 0.0 83.7 0.1 12.9 15.2 0.1 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.2 0.0 0.1 0.3 0.0 15.2 5.3 1.1 0.2 22.5 10.7 4.4 0.3 0.0 0.2 1.2 8.0 2.5 29.4 27.9 24.9 32.3 25.6 24.1 28.7 27.2 29.3 24.3 32.2 24.0 109.4 22.4 6.1 0.3 10.1 9.4 0.3 0.2 1.2 0.2 1.9 17.1 91.7 4.3 1.3 0.0 0.0 0.6 0.8 0.1 0.0 1.2 1.3 2.9 5.3 105.1 0.0 5.7 0.4 0.2 12.4 22.5 1.1 0.9 2.5 134.1 134.6 16.3 1.0 0.0 0.3 0.0 0.0 6.5 13.0 3.1 19.9 1.7 10.6 30.9 0.0 0.3 0.0 4.0 0.3 0.5 0.0 49.7 1.7 0.3 0.0 0.5 0.8 0.9 26.3 4.2 35.4 0.8 2.1 0.6 6.7 1.0 2.3 1.8 0.0 0.3 LIMS4 LIMS3L ENSG00000256671 "LIM zinc finger domain containing 4" P0CW20 2 110446640-110473075 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 1.5;Glandular and luminal cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.0;hTEC/SVTERT24-B: 1.8;HUVEC TERT2: 1.0;U-138 MG: 1.9" HPA058455 Uncertain Uncertain "Focal adhesion sites,Cytosol" NA NA "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Cytosol "Focal adhesion sites" "HPA058455: AB_2683723" "unprognostic (2.12e-1)" 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.8 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.3 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 LMAN1 "ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60" ENSG00000074695 "Lectin, mannose binding 1" P49257 18 59327823-59359265 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 502.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002320, CAB037163" Supported Supported "Endoplasmic reticulum,Vesicles" NA NA 18000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Endoplasmic reticulum" "CAB037163: AB_532237, HPA002320: AB_1079256" "unprognostic (5.64e-2)" "unprognostic (8.96e-3)" "unprognostic (4.20e-3)" "unprognostic (1.61e-1)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (1.65e-1)" "unprognostic (5.40e-3)" "unprognostic (1.16e-1)" "unprognostic (2.03e-1)" "unprognostic (2.40e-2)" "unprognostic (1.06e-1)" "unprognostic (5.79e-2)" "unprognostic (4.28e-2)" "unprognostic (5.37e-3)" "unprognostic (7.05e-2)" "unprognostic (3.71e-3)" 36.0 43.3 14.8 39.4 16.4 21.7 43.8 16.9 19.4 66.0 20.1 34.1 45.7 46.1 52.9 31.1 48.8 31.9 42.6 13.8 19.4 64.5 181.1 33.6 28.4 17.1 16.0 43.3 53.1 74.3 32.7 54.8 17.4 58.4 39.3 40.0 69.0 43.7 33.3 20.3 49.1 37.7 16.2 27.4 59.3 21.2 16.0 32.1 86.5 41.1 34.8 40.1 21.2 20.4 90.6 52.7 55.1 46.4 125.6 215.6 110.7 159.6 227.9 105.7 140.5 52.7 85.2 16.0 110.7 191.0 75.7 108.1 79.0 90.5 191.0 61.7 50.4 52.5 65.4 109.5 148.9 183.6 77.0 144.7 106.8 102.5 208.1 198.1 108.1 54.3 89.7 173.6 104.2 24.5 53.5 37.9 37.8 45.8 64.5 60.0 100.1 176.0 58.9 67.6 37.5 40.9 80.6 78.0 91.6 76.8 57.8 70.8 89.8 170.5 59.9 55.2 94.0 131.6 71.3 76.2 179.1 96.0 142.6 6.0 2.5 0.7 7.3 3.7 10.0 7.1 7.9 7.7 3.5 5.1 7.5 7.7 0.3 10.0 2.1 8.8 9.6 4.0 14.8 16.4 16.9 19.4 13.8 19.4 17.1 16.0 17.4 16.2 16.0 20.4 120.0 102.5 97.1 15.0 104.0 69.8 120.3 213.5 84.8 39.2 104.5 97.2 134.6 71.4 171.2 80.9 106.3 149.3 86.7 32.8 21.5 130.6 28.1 117.5 203.7 97.7 51.6 49.6 17.2 84.6 304.8 162.4 106.0 200.7 33.6 96.9 75.0 394.0 80.2 58.9 22.1 181.4 107.8 41.9 40.1 10.3 110.6 52.5 67.6 22.5 53.5 76.8 54.6 20.1 33.5 71.6 45.5 85.4 502.1 214.1 95.5 75.6 164.7 66.7 65.7 95.4 142.3 47.2 65.1 80.7 57.0 231.2 69.5 149.6 89.7 129.5 LMO7 "FBX20, FBXO20, KIAA0858" ENSG00000136153 "LIM domain 7" Q8WWI1 13 75620434-75859870 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 248.8" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 1682.7;Urothelial cells: 435.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 177 "amygdala: 12.6;basal ganglia: 19.9;cerebral cortex: 25.6;hippocampal formation: 14.9;white matter: 15.4" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 13.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 343.4;fHDF/TERT166: 568.2;LHCN-M2: 525.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 20.8;basal ganglia: 32.8;cerebral cortex: 26.6;hippocampal formation: 33.8" "HPA020923, HPA050184" Enhanced Supported "Actin filaments,Cytosol" NA NA 8200 "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" Cytosol "HPA020923: AB_1852963, HPA050184: AB_2681045" "unprognostic (2.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.75e-2)" "unprognostic (1.44e-1)" "unprognostic (1.57e-2)" "unprognostic (1.97e-1)" "unprognostic (1.52e-2)" "unprognostic (3.42e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.14e-1)" "prognostic favorable (7.75e-12)" "unprognostic (2.49e-1)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (8.33e-2)" 4.4 5.3 12.6 10.6 19.9 4.1 9.3 0.0 25.6 12.8 4.8 47.4 66.3 5.7 12.1 153.7 14.5 43.3 248.8 14.9 0.0 44.1 61.9 178.7 11.0 0.0 0.0 18.6 25.5 11.8 6.4 41.3 0.0 27.3 32.5 4.8 32.4 15.1 143.5 21.1 79.7 7.9 0.0 5.0 62.7 18.2 0.0 56.8 53.5 99.5 37.1 24.5 38.4 15.4 77.8 43.6 1.7 1.3 86.5 61.4 14.9 343.4 168.3 85.4 91.6 107.4 97.8 6.6 25.7 568.2 21.2 73.5 18.9 16.6 97.8 105.4 4.5 47.8 229.2 102.2 25.0 15.3 24.0 42.0 31.1 37.0 42.3 207.9 36.2 14.7 1.7 0.5 525.9 30.4 11.6 6.4 2.2 119.6 65.0 7.2 159.5 1.6 36.0 18.1 5.4 11.6 62.2 10.8 13.8 8.6 14.0 11.3 55.6 208.7 38.7 25.4 84.9 22.6 18.4 27.8 61.6 17.0 97.0 4.5 0.2 2.7 0.6 0.5 0.9 1.1 3.2 1.0 0.4 2.3 13.6 8.6 0.1 0.6 0.4 1.1 1.4 2.6 12.6 19.9 0.0 25.6 14.9 0.0 0.0 0.0 0.0 0.0 0.0 15.4 1.5 1682.7 279.7 22.2 4.3 24.0 74.7 59.9 72.8 6.8 10.5 13.2 362.6 51.5 317.2 62.5 2.1 45.5 3.6 378.5 15.6 81.5 6.2 92.0 19.0 9.0 71.2 3.6 162.3 37.8 8.7 38.0 276.3 244.4 20.3 9.5 6.1 72.7 6.0 6.7 82.5 96.6 67.1 3.5 4.4 8.0 42.0 6.4 16.0 39.4 2.8 1.9 3.1 30.7 48.4 228.8 351.2 42.5 2.1 344.9 213.8 15.5 199.5 10.5 13.1 27.2 18.1 11.2 6.3 100.9 45.3 17.0 12.9 2.5 75.2 435.7 LMOD1 "1D, 64kD, D1" ENSG00000163431 "Leiomodin 1" P29536 1 201896456-201946588 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 513.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 135.5;Leydig cells: 125.6;Peritubular cells: 275.3;Rod photoreceptor cells: 70.2;Sertoli cells: 197.2;Smooth muscle cells: 224.3" "Cancer enhanced" "Detected in all" "prostate cancer: 43.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 15.8;BJ: 21.3;BJ hTERT+: 34.4;fHDF/TERT166: 17.4;HSkMC: 14.5;hTERT-RPE1: 54.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028325, HPA028435, HPA030097" Enhanced Approved Cytosol No No "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA028325: AB_10600300, HPA028435: AB_10602180, HPA030097: AB_10601223" "unprognostic (3.84e-2)" "unprognostic (5.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.27e-1)" "unprognostic (5.64e-1)" "unprognostic (6.35e-2)" "prognostic favorable (2.52e-5)" "unprognostic (1.27e-1)" "unprognostic (6.10e-2)" "unprognostic (1.73e-2)" "unprognostic (3.51e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.30e-2)" "unprognostic (2.72e-1)" "unprognostic (4.44e-3)" "unprognostic (1.15e-2)" 157.7 52.5 7.8 28.5 9.7 0.0 75.4 5.7 9.1 161.9 5.5 513.9 25.1 309.5 49.7 135.8 194.7 85.5 31.7 6.2 8.0 11.8 5.1 44.3 7.3 13.6 6.5 72.2 8.4 18.2 5.8 35.3 6.8 165.2 46.9 48.0 21.2 242.5 137.5 43.2 115.5 206.6 5.4 18.5 218.6 17.9 9.1 2.5 39.8 45.7 1.6 368.7 111.9 7.2 0.0 0.1 0.4 1.2 15.8 2.0 1.3 21.3 34.4 1.3 1.5 0.1 0.2 0.0 0.7 17.4 0.2 0.3 0.5 0.0 0.4 0.0 1.4 0.0 0.1 0.0 1.5 0.1 0.1 14.5 0.0 1.0 0.0 54.4 0.1 0.0 0.2 0.2 0.7 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.5 0.1 0.4 0.1 0.3 0.0 0.5 0.4 9.5 0.7 0.0 0.0 0.1 0.8 0.3 0.0 0.7 0.6 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 9.7 5.7 9.1 6.2 8.0 13.6 6.5 6.8 5.4 9.1 7.2 16.1 0.0 1.1 8.5 0.3 1.3 1.0 0.3 0.0 4.8 1.6 40.8 25.1 0.0 0.0 0.0 135.5 1.7 0.0 0.1 0.0 0.0 2.1 2.6 64.5 5.8 0.0 0.0 0.5 0.6 0.3 20.4 0.5 1.2 0.0 0.7 9.3 0.4 1.0 3.3 1.0 0.0 0.0 0.0 2.3 8.2 125.6 0.9 3.6 3.7 0.0 7.3 0.0 4.0 1.0 0.0 0.0 275.3 0.0 0.9 0.0 0.1 0.9 70.2 197.2 5.2 224.3 1.2 0.5 0.8 2.3 1.2 1.3 2.1 0.0 0.4 LNPK "KIAA1715, LNP, LNP1, Ul" ENSG00000144320 "Lunapark, ER junction formation factor" Q9C0E8 2 175923882-176002839 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 19.3;Endometrial stromal cells: 24.6;Hofbauer cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 159.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014205 Approved Supported "Nucleoplasm,Endoplasmic reticulum" NA NA 15000 "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" Nucleoplasm "HPA014205: AB_2234186" "unprognostic (4.93e-2)" "unprognostic (3.35e-2)" "unprognostic (1.20e-1)" "unprognostic (7.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-2)" "unprognostic (8.73e-2)" "unprognostic (1.27e-1)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (3.13e-1)" "unprognostic (4.17e-3)" "unprognostic (1.63e-1)" "unprognostic (9.27e-2)" "unprognostic (2.35e-3)" "unprognostic (3.43e-2)" 13.5 8.9 6.3 7.7 10.1 30.1 9.8 10.2 8.7 12.0 4.2 12.0 7.6 8.6 6.2 13.1 6.3 7.7 12.2 7.6 13.2 8.2 14.4 6.7 7.2 11.3 9.2 10.7 5.5 15.6 6.0 6.1 14.1 10.1 10.2 24.1 6.4 8.2 34.1 12.1 7.5 9.6 11.3 5.9 7.8 24.5 9.3 14.0 8.8 26.8 7.9 7.6 9.2 19.0 24.5 12.3 28.3 40.1 58.5 36.1 14.3 70.8 33.7 32.2 45.1 17.0 28.2 24.4 39.4 31.5 42.3 26.5 26.9 18.9 44.6 37.5 27.4 27.6 14.8 15.2 13.8 47.2 32.9 29.9 17.5 31.4 15.4 26.4 6.0 19.3 28.9 31.5 44.9 16.0 31.4 18.8 9.2 24.9 23.4 31.3 28.6 18.0 13.6 22.2 32.6 32.9 31.3 17.5 24.1 26.6 26.2 15.4 9.2 159.0 23.6 53.9 33.7 18.5 36.6 20.3 49.4 15.2 30.4 3.7 4.2 7.9 4.9 4.8 5.8 4.3 4.2 5.4 3.9 3.3 4.2 6.7 3.4 6.5 4.5 4.4 7.8 3.4 6.3 10.1 10.2 8.7 7.6 13.2 11.3 9.2 14.1 11.3 9.3 19.0 10.8 19.2 13.6 0.0 4.4 0.0 0.0 0.0 0.0 0.0 19.3 15.0 0.0 0.0 6.2 16.5 0.0 5.7 14.5 0.0 5.9 14.0 0.0 10.1 24.6 3.5 0.0 0.0 0.0 9.6 17.3 12.8 0.0 12.7 11.4 10.6 0.0 0.0 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 3.3 0.0 0.0 9.1 8.7 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 8.3 7.2 12.0 0.0 0.0 LOX ENSG00000113083 "Lysyl oxidase" P28300 5 122063195-122078413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 27.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 67.1;Club cells: 38.4;Early spermatids: 41.9;Endometrial stromal cells: 34.0;Extravillous trophoblasts: 44.2;Fibroblasts: 79.1;Peritubular cells: 39.1;Smooth muscle cells: 32.7" "Cancer enhanced" "Detected in all" "renal cancer: 39.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 777.3;fHDF/TERT166: 1790.7;HSkMC: 356.3;U-138 MG: 475.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043930 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 550000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA043930: AB_2678736" "unprognostic (5.10e-2)" "unprognostic (1.03e-2)" "unprognostic (6.99e-3)" "unprognostic (3.64e-2)" "unprognostic (9.86e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.42e-3)" "unprognostic (3.06e-3)" "unprognostic (8.92e-2)" "unprognostic (3.21e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (3.93e-8)" "unprognostic (1.11e-3)" "unprognostic (9.92e-2)" "unprognostic (4.31e-2)" "prognostic unfavorable (3.32e-4)" 27.9 2.4 0.4 6.8 0.4 0.2 17.6 0.5 0.9 10.8 0.8 4.2 3.8 6.2 1.7 5.6 8.9 18.8 23.9 0.3 0.4 4.5 2.1 13.6 3.3 1.3 1.4 5.4 3.3 0.9 1.2 8.1 0.8 4.1 4.5 1.1 3.2 2.6 1.9 12.4 3.7 10.0 1.2 2.6 4.4 1.4 0.5 0.9 6.9 2.1 1.4 14.1 4.8 1.0 0.8 0.2 2.0 0.9 168.7 185.2 0.1 777.3 205.3 73.2 246.4 0.5 0.3 0.1 16.5 1790.7 3.7 0.2 4.5 3.5 196.4 0.1 2.0 0.0 16.3 9.3 203.4 0.4 0.1 356.3 4.4 137.6 7.4 329.3 95.3 0.1 0.0 0.1 83.6 0.0 0.1 0.3 6.4 0.1 1.9 0.1 7.4 0.9 4.9 0.5 0.5 4.2 72.1 0.1 12.9 29.8 0.6 0.6 6.8 475.5 23.2 272.8 9.3 0.0 0.1 0.2 207.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.3 0.4 1.3 1.4 0.8 1.2 0.5 1.0 20.0 9.6 1.1 0.0 0.2 7.8 1.9 67.1 0.0 0.6 1.3 1.1 2.1 0.0 38.4 0.0 0.0 0.8 0.1 0.0 0.0 7.2 41.9 8.4 34.0 9.4 0.0 0.0 0.3 0.6 44.2 79.1 0.0 6.6 0.0 0.1 10.8 0.5 2.2 1.7 2.0 0.0 2.0 0.8 21.6 5.0 14.0 1.3 5.4 1.9 0.6 0.0 0.0 0.0 0.0 1.3 0.0 39.1 0.3 2.8 0.0 0.1 8.3 1.7 19.7 1.1 32.7 0.8 0.6 1.8 10.7 4.8 1.1 0.4 0.1 0.9 LOXL1 "LOL, LOXL" ENSG00000129038 "Lysyl oxidase like 1" Q08397 15 73925989-73952137 "Disease related genes, Plasma proteins, Predicted secreted proteins" Oxidoreductase Glaucoma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.3;Extravillous trophoblasts: 145.8;Fibroblasts: 76.0;Smooth muscle cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 3.4" "Lineage enriched" "Detected in single" 34 "T-cells: 3.4" "Cell line enhanced" "Detected in many" "BJ: 66.5;BJ hTERT+: 75.2;hTERT-RPE1: 73.7;U-87 MG: 61.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042111, HPA063583" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 280000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA042111: AB_10794412, HPA063583: AB_2685050" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (3.05e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.52e-5)" "unprognostic (7.95e-2)" "unprognostic (2.49e-1)" "unprognostic (2.44e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.63e-1)" "unprognostic (9.83e-2)" "unprognostic (1.14e-3)" "unprognostic (4.51e-2)" "unprognostic (5.81e-2)" "unprognostic (1.41e-2)" "unprognostic (9.76e-2)" 12.4 3.1 1.4 5.4 0.8 0.8 6.8 0.2 1.4 12.7 12.3 10.2 1.9 16.0 1.4 4.7 8.3 5.0 27.9 1.7 1.9 8.7 1.5 10.1 4.4 1.4 1.7 8.0 3.3 2.2 9.2 8.0 1.1 15.3 1.4 0.0 7.6 11.9 3.8 6.4 5.6 4.9 0.8 3.2 7.8 2.4 1.9 0.9 5.2 1.9 2.3 16.6 14.8 0.6 3.3 0.0 0.9 0.0 45.6 54.8 2.2 66.5 75.2 27.6 48.7 1.3 1.7 0.0 12.1 49.1 6.9 19.9 0.3 0.2 6.5 0.0 4.3 0.2 2.0 0.3 6.2 0.0 0.1 45.0 0.0 20.8 0.2 73.7 1.0 1.2 0.0 0.3 33.3 2.4 0.4 1.3 6.3 4.4 45.1 0.0 38.7 0.6 2.5 12.0 5.5 0.0 2.0 0.4 0.0 6.5 0.4 0.0 4.9 53.8 47.0 42.8 25.8 0.2 0.0 0.0 61.9 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.9 0.0 1.3 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 3.4 0.2 1.4 0.8 0.2 1.4 1.7 1.9 1.4 1.7 1.1 0.8 1.9 0.6 4.1 0.0 0.6 3.3 0.1 5.9 7.6 6.0 4.0 0.9 2.3 4.8 92.3 2.8 0.9 9.2 0.0 2.2 0.6 0.1 3.9 5.2 1.7 9.2 8.0 4.1 3.5 0.0 0.5 1.3 145.8 76.0 8.6 9.3 1.3 5.5 12.1 0.1 6.6 0.0 0.4 0.6 2.0 0.0 6.2 1.3 9.9 0.9 10.6 0.0 0.1 6.4 0.0 1.5 0.3 12.2 0.1 21.1 0.1 4.8 0.4 2.5 1.2 0.4 0.0 6.0 32.7 8.9 4.9 2.4 3.4 5.1 3.4 0.3 1.1 5.0 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 41.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 26.9;Endometrial stromal cells: 26.9;Endothelial cells: 33.1;Extravillous trophoblasts: 22.0;Fibroblasts: 22.9;Hepatic stellate cells: 19.6;Sertoli cells: 26.3;Smooth muscle cells: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 935.5;BJ hTERT+ SV40 Large T+ RasG12V: 517.3;fHDF/TERT166: 602.7;TIME: 510.7;U-87 MG: 905.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 30.4 3.3 1.9 15.9 2.7 1.2 18.8 4.7 3.0 10.6 0.8 25.3 9.3 12.0 0.9 3.8 4.9 8.0 10.7 1.8 3.2 6.1 3.9 8.3 11.7 7.7 8.1 12.9 6.5 2.5 2.6 36.2 7.0 7.5 5.4 3.0 4.1 13.0 4.5 5.4 10.3 41.3 4.5 5.0 9.0 2.3 4.5 1.8 5.2 2.6 9.5 12.0 7.3 3.7 58.2 147.7 42.7 35.8 112.4 183.8 19.4 935.5 295.9 415.6 517.3 1.1 4.4 10.7 7.5 602.7 193.2 47.6 2.1 79.0 215.3 1.8 8.5 0.9 19.4 1.0 226.8 0.5 3.8 164.6 3.9 155.0 20.8 274.0 350.7 2.4 0.5 2.0 138.1 32.3 0.6 1.4 29.1 0.4 24.5 1.9 36.7 0.4 120.1 0.3 0.9 13.7 122.9 6.1 8.6 131.3 0.8 1.2 510.7 384.6 103.3 163.8 127.3 4.1 0.8 29.9 905.4 1.4 413.5 0.1 0.2 0.8 0.4 0.1 0.2 0.4 0.1 0.3 0.1 0.1 0.2 0.6 0.3 0.1 0.2 0.2 0.1 0.2 1.9 2.7 4.7 3.0 1.8 3.2 7.7 8.1 7.0 4.5 4.5 3.7 12.9 0.0 3.0 6.8 0.6 2.5 0.3 26.9 0.6 1.5 0.6 9.7 2.6 1.5 4.1 0.0 0.0 2.7 0.4 0.0 0.0 1.9 0.6 1.7 26.9 33.1 0.0 0.0 8.1 1.5 22.0 22.9 1.5 2.1 0.0 2.0 19.6 0.2 1.3 1.7 3.2 0.1 0.0 0.3 5.7 0.4 0.9 0.9 3.6 6.5 0.0 1.2 0.0 7.1 11.9 2.3 0.1 0.4 0.9 0.6 0.2 0.2 1.6 3.2 26.3 2.7 48.1 1.3 1.6 0.5 3.1 1.0 1.0 3.1 0.4 0.2 LRP12 "FLJ12929, ST7" ENSG00000147650 "LDL receptor related protein 12" Q9Y561 8 104489231-104589258 "Disease related genes, Human disease related genes, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 42.7;Excitatory neurons: 78.7;Inhibitory neurons: 53.7;Oligodendrocyte precursor cells: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "basophil: 47.0" "Lineage enriched" "Detected in many" 32 "granulocytes: 47.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017245 Uncertain Approved "Nucleoli fibrillar center,Plasma membrane,Mitochondria" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center, Plasma membrane, Mitochondria" "HPA017245: AB_1857532" "unprognostic (2.17e-1)" "unprognostic (6.80e-2)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.07e-1)" "unprognostic (2.15e-3)" "unprognostic (4.87e-4)" "unprognostic (2.96e-2)" "unprognostic (3.96e-1)" "unprognostic (4.59e-2)" "unprognostic (1.32e-1)" "unprognostic (3.39e-2)" "unprognostic (9.89e-2)" "unprognostic (7.56e-3)" "unprognostic (4.88e-2)" "unprognostic (1.45e-1)" "unprognostic (4.05e-3)" 5.7 4.7 5.1 3.9 8.8 2.2 4.3 4.7 9.4 6.4 3.1 4.8 3.1 16.5 4.0 4.1 5.8 7.5 13.6 13.8 5.3 6.5 1.5 4.6 1.6 1.8 2.3 6.1 4.5 10.0 3.1 5.3 1.1 6.5 4.8 6.1 3.8 5.9 9.3 3.1 3.0 18.5 2.4 3.7 2.8 4.9 3.1 12.9 6.8 17.2 2.3 7.6 3.2 3.9 18.5 10.6 21.1 37.1 23.4 18.4 4.7 51.5 51.3 17.6 24.6 2.4 17.7 0.0 20.2 49.0 21.2 8.1 8.6 22.0 37.7 34.3 8.2 28.7 4.7 0.8 14.4 0.4 22.1 24.8 15.4 29.5 23.7 63.4 9.1 21.9 6.2 0.0 63.9 3.0 26.5 0.6 5.3 1.6 18.2 2.1 20.5 4.0 13.9 0.8 27.0 16.4 16.4 0.7 44.6 15.8 5.0 5.6 25.7 48.1 31.0 15.7 33.6 23.8 20.2 0.2 25.9 0.0 53.9 47.0 0.3 5.8 0.2 0.8 1.4 0.0 1.0 0.1 0.1 0.0 0.2 0.2 0.2 0.8 0.5 0.4 0.1 0.4 5.1 8.8 4.7 9.4 13.8 5.3 1.8 2.3 1.1 2.4 3.1 3.9 4.4 16.0 2.2 42.7 0.2 11.5 6.3 12.3 10.8 17.5 3.9 4.3 11.7 7.2 5.2 14.7 6.2 0.2 1.7 2.0 0.0 4.6 4.3 4.4 16.4 5.9 14.4 2.5 78.7 4.5 0.5 12.6 1.5 5.5 8.2 10.9 4.2 0.8 5.3 28.6 53.7 2.5 10.2 7.9 14.3 2.7 8.7 8.2 7.2 9.4 6.1 3.1 1.0 64.3 25.2 5.1 0.3 9.1 0.1 7.7 1.5 3.8 5.3 8.3 6.6 8.2 11.3 8.5 12.0 3.2 10.9 0.3 3.9 4.5 2.3 5.2 LRRC15 LIB ENSG00000172061 "Leucine rich repeat containing 15" Q8TF66 3 194355249-194369743 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.9;skin 1: 7.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.9;Endothelial cells: 1.0;Fibroblasts: 2.3;Hepatic stellate cells: 1.8;Langerhans cells: 3.0;Suprabasal keratinocytes: 1.4" "Cancer enhanced" "Detected in many" "breast cancer: 25.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "fHDF/TERT166: 120.6;U-87 MG: 62.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA035503 Uncertain Approved "Vesicles,Plasma membrane" NA NA 1700000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA035503: AB_10961253" "unprognostic (3.20e-2)" "unprognostic (1.45e-2)" "unprognostic (3.11e-1)" "unprognostic (6.30e-2)" "unprognostic (1.19e-2)" "unprognostic (2.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (3.53e-2)" "unprognostic (3.97e-2)" "unprognostic (1.88e-3)" "unprognostic (1.22e-8)" "unprognostic (5.81e-2)" "unprognostic (1.11e-1)" "unprognostic (5.62e-3)" "unprognostic (7.54e-3)" 1.1 0.1 0.0 1.3 0.0 0.0 3.7 0.0 0.0 2.9 0.0 1.7 0.5 1.9 0.0 0.5 1.1 1.6 0.2 0.0 0.0 0.0 0.1 2.0 0.8 0.0 0.1 0.2 0.1 0.1 0.0 2.2 0.0 0.1 3.0 0.0 1.0 0.0 0.1 7.3 0.4 0.6 0.0 1.3 1.5 0.0 0.1 0.2 1.3 0.2 4.9 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.7 0.1 0.1 0.4 0.0 0.0 1.0 120.6 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 22.5 3.7 3.0 0.0 0.0 0.0 0.0 62.7 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 LRRC2 ENSG00000163827 "Leucine rich repeat containing 2" Q9BYS8 3 46515385-46580099 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 45.3;skeletal muscle: 165.0;tongue: 94.1" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 198.4" "Cancer enhanced" "Detected in some" "thyroid cancer: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 7.2;HEL: 4.2;LHCN-M2: 4.1;TIME: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039138, HPA064844" Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Nuclear bodies, Cytosol" "HPA039138: AB_10795461, HPA064844: " "unprognostic (1.32e-4)" "unprognostic (3.44e-3)" "unprognostic (2.29e-2)" "unprognostic (3.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.44e-1)" "unprognostic (7.38e-3)" "unprognostic (1.61e-1)" "unprognostic (7.42e-2)" "unprognostic (1.45e-1)" "unprognostic (3.72e-3)" "unprognostic (2.17e-1)" "unprognostic (2.23e-2)" "unprognostic (1.09e-1)" "unprognostic (2.53e-1)" "unprognostic (1.96e-2)" "unprognostic (1.24e-1)" 2.4 0.7 1.5 0.7 3.6 0.8 1.9 1.1 2.8 3.5 0.2 1.9 0.7 4.8 2.4 1.4 2.4 3.0 45.3 2.7 0.1 4.5 5.6 1.2 0.5 0.4 0.4 5.2 1.1 0.9 1.2 0.9 0.3 2.1 1.6 0.3 2.2 0.3 165.0 1.9 0.8 4.0 0.2 2.8 1.8 0.8 0.1 3.2 22.1 94.1 0.7 2.3 2.0 1.4 0.1 0.0 0.1 0.1 0.6 1.4 0.1 0.5 1.0 0.3 0.5 0.0 0.1 0.2 0.1 7.2 0.0 0.1 2.5 0.0 0.9 0.3 0.0 4.2 0.3 0.0 0.1 0.1 0.0 0.1 0.0 2.8 0.0 2.3 0.1 0.5 0.0 0.2 4.1 0.0 0.5 0.1 1.0 0.3 0.1 0.1 0.0 0.2 0.0 0.2 0.3 0.8 0.5 0.1 1.0 0.7 0.1 0.5 3.2 0.1 0.3 1.6 1.1 0.2 0.2 1.9 0.1 0.1 0.9 0.6 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.1 0.5 0.2 0.1 0.1 0.5 0.1 1.5 3.6 1.1 2.8 2.7 0.1 0.4 0.4 0.3 0.2 0.1 1.4 1.6 9.6 1.1 2.0 0.2 1.9 1.1 0.6 0.6 0.1 0.8 1.3 198.4 7.2 0.0 1.8 0.0 0.1 0.0 0.2 9.8 0.6 2.3 0.3 1.6 4.0 3.0 0.0 12.5 1.0 0.0 11.9 3.1 0.4 10.2 2.5 5.0 10.2 2.0 0.0 11.2 1.8 0.0 0.8 5.7 2.9 0.6 0.6 10.6 3.7 0.0 0.4 0.0 3.5 0.7 1.0 0.4 0.0 3.0 0.6 0.0 0.8 0.7 0.2 0.0 32.7 2.6 0.6 0.7 0.0 2.4 0.1 2.1 7.9 1.9 0.4 LRRFIP2 HUFI-2 ENSG00000093167 "LRR binding FLII interacting protein 2" Q9Y608 3 37052626-37183689 "Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 516.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035956, HPA042023" Uncertain Approved "Plasma membrane,Actin filaments" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA035956: AB_10671238, HPA042023: AB_2677802" "unprognostic (2.03e-3)" "prognostic favorable (6.31e-4)" "unprognostic (1.16e-2)" "unprognostic (7.90e-2)" "unprognostic (2.48e-1)" "unprognostic (2.97e-1)" "unprognostic (5.41e-2)" "unprognostic (1.82e-1)" "unprognostic (3.09e-2)" "unprognostic (2.56e-2)" "unprognostic (4.99e-3)" "unprognostic (1.98e-1)" "unprognostic (4.13e-3)" "unprognostic (2.62e-1)" "unprognostic (1.37e-1)" "unprognostic (4.84e-3)" "unprognostic (3.76e-2)" 23.4 24.0 43.7 20.1 46.9 44.3 22.3 43.6 49.0 46.0 33.6 38.3 35.4 31.8 19.7 52.6 25.8 22.0 75.8 38.8 44.4 24.0 48.5 27.0 18.1 43.4 42.0 27.4 19.2 33.3 18.6 20.8 44.8 41.0 34.2 36.0 28.5 24.3 97.9 37.0 36.2 31.5 41.0 45.0 26.5 71.8 46.4 18.8 27.5 45.3 23.2 24.2 40.9 60.9 56.6 30.8 34.9 27.7 45.5 69.3 30.5 149.9 148.2 82.6 94.3 29.0 25.3 22.2 24.0 145.4 40.8 28.8 25.8 74.2 134.3 49.7 20.2 39.8 44.0 28.6 64.8 31.9 23.3 31.1 52.1 107.8 110.4 45.8 58.2 34.0 32.3 37.8 69.5 14.4 27.2 17.0 23.0 23.0 39.2 13.0 99.2 22.6 58.4 21.7 12.6 19.9 57.9 53.0 49.4 28.0 30.6 32.6 56.5 63.1 42.6 93.4 71.5 29.1 57.1 33.9 37.1 28.1 91.4 20.5 21.4 33.8 8.8 14.9 11.3 9.7 9.3 9.5 14.1 8.5 6.8 8.3 19.2 16.9 26.9 7.9 13.0 11.7 43.7 46.9 43.6 49.0 38.8 44.4 43.4 42.0 44.8 41.0 46.4 60.9 47.8 28.9 36.5 98.6 29.1 136.1 143.0 41.3 113.8 36.3 64.7 53.2 123.1 38.6 53.7 23.9 29.2 29.2 28.7 117.2 64.6 89.8 516.2 78.9 44.0 59.9 54.0 60.0 169.8 94.3 46.1 57.4 37.8 127.3 52.6 29.4 56.7 58.8 24.9 122.8 197.7 45.6 28.5 35.6 128.3 330.7 42.3 48.2 74.7 62.8 67.7 51.9 30.9 130.7 309.0 109.9 90.1 57.6 45.8 325.6 125.8 46.1 36.2 51.9 39.5 32.4 72.8 159.9 73.4 139.3 170.5 39.3 34.1 90.0 66.0 303.2 LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 966.4;Fibroblasts: 2136.1;Leydig cells: 401.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 1991.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" 161.5 133.5 0.6 68.1 0.7 0.3 153.2 0.6 5.6 199.8 4.2 85.0 56.1 301.0 88.3 75.7 59.2 739.0 183.8 0.7 0.9 85.0 34.6 211.4 41.3 0.9 0.8 92.9 72.9 26.3 5.3 535.9 0.8 115.2 133.0 5.7 14.3 67.4 9.6 20.0 90.6 354.5 0.7 4.8 47.1 17.5 1.3 13.4 30.8 73.0 80.3 486.0 39.2 0.8 0.0 0.3 6.9 0.0 237.4 115.9 0.7 400.8 1991.0 16.0 24.3 0.0 0.1 0.0 0.0 339.9 0.0 0.6 0.0 0.0 5.4 0.0 0.0 0.0 21.5 0.0 183.7 0.6 0.1 160.5 0.0 33.7 1.0 0.9 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.6 1.2 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.3 14.9 0.1 0.0 10.8 16.3 0.0 0.0 0.0 17.0 4.5 14.3 0.0 0.2 0.0 0.0 8.8 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.6 5.6 0.7 0.9 0.9 0.8 0.8 0.7 1.3 0.8 77.5 12.8 30.9 0.0 0.6 97.6 1.2 0.8 3.4 0.2 9.4 8.6 15.2 0.0 5.0 0.0 2.1 44.9 4.0 0.1 0.0 0.7 3.5 27.0 966.4 27.2 0.0 0.0 0.0 0.0 38.9 2136.1 8.6 15.2 18.3 0.0 55.0 0.3 63.6 0.0 0.2 0.3 0.0 0.3 143.5 8.7 401.7 9.5 117.4 16.9 1.0 86.9 0.0 0.0 0.0 2.1 0.0 44.8 6.3 4.9 0.4 0.3 0.8 3.0 0.0 39.1 165.5 0.2 0.9 5.9 100.2 84.0 14.5 27.4 0.0 4.1 LYPD6 MGC52057 ENSG00000187123 "LY6/PLAUR domain containing 6" Q86Y78 2 149329985-149474138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;placenta: 15.7" "Cell type enhanced" "Detected in many" "Astrocytes: 40.8;Early spermatids: 59.7;Inhibitory neurons: 65.9;Late spermatids: 230.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 37.6;fHDF/TERT166: 48.2;HBF TERT88: 25.0;LHCN-M2: 46.2;RT4: 39.9" "Low region specificity" "Detected in all" HPA042805 Enhanced Approved Cytosol "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA042805: AB_10794159" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (7.23e-3)" "unprognostic (1.64e-2)" "unprognostic (3.25e-1)" "unprognostic (6.49e-3)" "unprognostic (6.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.73e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.14e-3)" "unprognostic (6.75e-2)" "unprognostic (7.33e-4)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.72e-4)" 1.4 0.3 8.0 0.6 4.6 0.0 9.3 4.5 5.5 0.9 1.2 1.5 1.7 2.1 0.1 0.5 1.6 11.1 0.6 4.7 9.8 2.0 0.3 0.2 0.2 6.8 24.0 0.6 1.9 1.4 0.3 15.7 6.7 1.4 2.5 7.0 0.2 1.3 0.1 0.6 1.4 2.9 5.6 0.6 3.9 6.8 16.1 0.3 0.2 0.1 1.3 2.6 0.4 4.2 0.2 0.0 6.8 37.6 0.0 0.1 0.5 15.0 6.6 18.9 11.7 0.2 3.0 0.0 0.8 48.2 9.1 3.8 5.3 0.1 25.0 0.0 1.7 0.1 9.6 0.0 0.2 0.0 0.0 0.0 0.4 0.0 11.0 0.4 0.3 0.0 0.0 0.0 46.2 6.7 0.0 3.6 5.4 3.2 4.3 0.0 20.1 0.0 2.3 39.9 1.5 6.7 10.1 11.2 1.2 12.2 1.5 0.8 0.0 0.4 5.7 0.5 8.2 0.0 0.0 0.0 3.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 4.6 4.5 5.5 4.7 9.8 6.8 24.0 6.7 5.6 16.1 4.2 0.1 0.0 0.0 40.8 0.0 0.1 0.6 1.0 1.2 2.7 11.7 6.6 0.4 10.0 2.0 0.0 0.0 0.0 0.0 0.4 3.9 2.6 59.7 1.7 0.4 0.9 0.0 0.0 0.3 0.9 0.2 1.4 10.7 2.5 0.0 0.7 0.4 0.0 0.3 0.0 65.9 2.8 0.0 0.0 0.0 230.4 3.1 0.0 0.0 1.0 0.0 4.1 0.0 13.6 1.0 4.5 0.4 0.4 0.1 2.1 1.7 0.0 0.8 3.4 0.0 0.1 0.2 1.0 5.2 0.7 0.0 0.3 0.1 0.0 2.0 1.7 LYPD6B "CT116, LYPD7" ENSG00000150556 "LY6/PLAUR domain containing 6B" Q8NI32 2 149038107-149215262 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 95.5" "Cell type enhanced" "Detected in many" "Early spermatids: 245.7;Gastric mucus-secreting cells: 87.7;Inhibitory neurons: 77.8;Late spermatids: 118.5;Suprabasal keratinocytes: 69.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 13.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.8" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 64.8;LHCN-M2: 102.3;NB-4: 34.7;RT4: 54.7;SK-BR-3: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049239 Uncertain "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "HPA049239: AB_2680688" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (3.12e-3)" "unprognostic (1.64e-1)" "unprognostic (3.37e-1)" "unprognostic (2.01e-2)" "unprognostic (6.27e-2)" "unprognostic (3.64e-2)" "unprognostic (7.95e-3)" "unprognostic (2.59e-2)" "unprognostic (4.40e-2)" "unprognostic (1.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (1.32e-3)" 0.3 0.2 3.5 0.4 2.5 0.2 16.4 1.6 5.3 2.8 1.6 1.7 2.6 0.9 1.2 4.1 23.4 37.3 0.0 4.3 4.1 20.5 0.9 1.7 0.4 2.3 7.3 0.4 12.3 16.1 0.4 0.8 3.0 11.1 3.3 1.0 5.8 15.2 0.2 95.5 1.2 0.3 1.9 2.8 41.3 34.1 8.0 0.3 0.2 0.0 1.9 14.2 6.3 2.1 1.4 0.0 0.0 1.5 0.0 0.1 0.1 8.0 1.5 6.6 2.5 1.0 0.0 0.0 0.0 64.8 0.0 14.0 1.5 1.3 20.6 0.0 7.4 0.0 1.9 0.0 0.2 0.0 0.1 0.6 21.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 102.3 24.3 0.0 34.7 2.0 14.6 0.3 0.0 0.4 4.3 3.2 54.7 3.9 0.1 0.4 32.1 0.0 6.3 4.8 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.8 13.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.5 2.5 1.6 5.3 4.3 4.1 2.3 7.3 3.0 1.9 8.0 2.1 0.5 0.0 2.0 2.3 5.5 29.8 21.0 30.6 6.2 0.0 23.4 17.1 1.4 42.9 23.9 46.0 0.0 0.1 0.1 4.0 7.9 12.4 245.7 5.2 0.3 1.0 2.4 2.7 4.6 19.1 0.7 0.8 87.7 5.7 0.0 0.4 0.0 0.1 0.1 0.0 77.8 3.9 8.2 0.0 2.8 118.5 2.1 0.4 5.4 0.0 0.6 0.0 0.0 0.0 0.4 30.9 6.0 0.0 4.5 40.6 5.7 0.2 21.4 0.0 0.0 0.0 1.3 4.2 1.7 3.5 69.0 0.3 1.1 0.0 3.5 53.7 MACIR "C5orf30, FLJ25291" ENSG00000181751 "Macrophage immunometabolism regulator" Q96GV9 5 103258763-103278660 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Inflammatory response, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 33.6" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 37.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 37.6" "Cell line enhanced" "Detected in many" "BJ: 177.1;fHDF/TERT166: 108.5;U-138 MG: 115.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043434 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA043434: AB_2678480" "unprognostic (1.18e-1)" "unprognostic (1.49e-1)" "unprognostic (6.59e-3)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.85e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (1.78e-5)" "unprognostic (1.15e-1)" "unprognostic (3.85e-2)" "unprognostic (8.76e-2)" "unprognostic (4.36e-2)" "unprognostic (1.88e-1)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (2.29e-1)" "unprognostic (5.23e-2)" "unprognostic (1.83e-2)" 8.0 4.1 21.6 4.4 24.3 31.4 9.9 22.0 33.6 3.5 17.8 22.6 9.6 2.2 3.1 4.8 6.1 8.1 4.0 24.2 20.5 5.8 1.0 3.8 2.7 22.5 23.0 4.6 8.0 11.3 4.0 7.6 22.0 6.5 21.7 20.8 3.2 5.0 8.4 5.9 11.7 3.4 22.5 4.3 13.2 5.9 24.4 4.1 5.2 3.4 2.5 2.8 2.7 32.9 10.6 22.2 21.8 12.9 12.0 14.2 13.9 177.1 50.1 21.4 19.5 1.4 23.2 0.1 17.1 108.5 12.6 12.2 12.6 15.1 33.5 30.1 20.6 18.0 28.3 7.1 6.1 9.1 11.4 10.9 19.5 8.7 17.1 38.3 12.8 13.2 9.1 24.2 24.8 13.5 5.2 13.2 14.9 5.7 13.6 26.4 14.5 38.7 9.2 10.1 23.0 21.2 6.3 11.7 45.2 15.4 24.3 10.3 33.6 115.6 9.5 24.8 29.9 13.6 22.6 19.6 14.5 5.1 45.7 37.6 3.6 6.2 3.4 3.2 2.9 4.1 2.8 3.6 3.5 2.0 2.5 2.4 3.2 7.3 3.7 2.0 7.3 3.0 21.6 24.3 22.0 33.6 24.2 20.5 22.5 23.0 22.0 22.5 24.4 32.9 2.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 22.5 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 103.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 21.5 0.5 0.0 0.0 0.0 MAGED1 "DLXIN-1, NRAGE" ENSG00000179222 "MAGE family member D1" Q9Y5V3 X 51803007-51902354 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 335.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 534.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043645 Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA043645: AB_2678597" "unprognostic (5.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.29e-2)" "unprognostic (1.39e-2)" "unprognostic (3.92e-2)" "unprognostic (1.37e-1)" "unprognostic (4.04e-3)" "unprognostic (2.04e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (3.15e-3)" "unprognostic (1.42e-1)" "unprognostic (6.10e-3)" "unprognostic (2.14e-3)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.71e-3)" 32.4 125.4 69.8 37.7 73.1 16.7 38.0 34.7 71.1 99.7 99.2 40.0 32.4 57.3 102.4 26.6 64.7 58.8 70.2 70.7 108.8 43.0 71.5 40.4 29.2 57.4 66.2 62.5 80.2 76.8 157.0 116.2 76.3 71.7 39.6 37.1 85.3 89.0 46.8 29.9 32.3 77.6 62.0 35.4 54.6 56.5 84.7 49.0 73.7 39.1 31.6 45.4 35.5 49.7 21.3 76.2 238.5 205.8 184.3 330.4 128.1 281.2 357.7 152.5 240.0 157.3 71.0 29.9 53.6 534.9 54.4 15.6 215.5 99.6 113.2 31.8 83.1 20.3 0.4 205.7 140.9 75.8 35.8 312.2 35.0 128.6 29.1 267.7 184.8 77.1 31.5 57.6 310.5 194.8 87.7 25.4 187.6 69.4 154.3 88.4 154.2 4.1 156.7 37.4 60.9 340.1 0.0 80.6 41.9 232.0 145.6 18.8 185.6 66.1 166.5 234.7 31.8 37.5 59.5 60.3 257.9 6.9 175.1 1.5 4.4 3.1 21.1 6.0 18.7 17.2 13.7 18.5 13.2 19.4 17.1 20.5 1.3 16.3 6.1 55.8 21.1 14.3 69.8 73.1 34.7 71.1 70.7 108.8 57.4 66.2 76.3 62.0 84.7 49.7 12.2 76.9 34.5 85.8 17.1 11.5 20.4 48.1 12.5 33.2 41.9 27.9 53.4 32.9 63.8 35.0 8.4 335.2 17.1 18.6 29.4 47.9 2.5 35.6 73.4 24.5 57.1 13.9 97.5 49.9 171.5 69.5 34.7 54.3 17.7 60.7 39.7 62.5 114.6 45.4 138.5 74.4 54.9 9.2 6.8 10.0 43.2 6.3 24.9 42.2 4.9 39.7 13.4 101.6 55.0 33.5 13.5 57.6 72.6 20.2 15.9 33.2 48.3 12.5 13.1 28.2 50.0 5.7 5.9 12.4 8.2 185.7 11.9 169.9 25.2 18.8 MAP2K3 "MAPKK3, MEK3, MKK3, PRKMK3" ENSG00000034152 "Mitogen-activated protein kinase kinase 3" P46734 17 21284672-21315232 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 212.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 325.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018548 Approved Supported Nucleoplasm,Cytosol NA NA 28000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "CAB018548: AB_631927" "unprognostic (2.31e-1)" "unprognostic (6.39e-2)" "unprognostic (4.63e-2)" "unprognostic (3.68e-1)" "unprognostic (3.54e-3)" "unprognostic (1.60e-1)" "unprognostic (2.97e-2)" "unprognostic (1.35e-2)" "unprognostic (5.25e-3)" "unprognostic (1.88e-2)" "unprognostic (3.16e-2)" "unprognostic (2.18e-2)" "unprognostic (1.33e-1)" "unprognostic (6.48e-2)" "unprognostic (1.22e-2)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" 47.3 32.5 12.9 35.3 12.1 212.4 30.7 17.6 23.2 22.7 22.6 33.1 49.0 17.1 14.5 62.7 29.9 40.0 66.7 11.5 14.4 45.7 95.7 67.5 34.0 13.6 14.3 12.6 33.6 17.9 37.1 28.9 14.2 28.9 24.1 6.0 45.3 16.5 132.7 53.1 41.0 22.5 14.3 60.4 42.8 6.2 15.8 20.9 24.0 74.6 41.1 54.1 33.4 17.0 75.5 73.9 9.7 44.5 57.7 36.6 36.3 113.0 121.8 88.3 80.5 82.9 46.6 68.1 44.7 178.3 74.2 72.4 31.0 100.5 62.1 69.5 56.9 39.2 42.0 76.1 18.2 51.9 76.7 28.5 28.2 120.6 35.9 27.7 40.0 38.6 7.7 33.2 74.7 74.1 25.5 49.3 28.1 134.1 42.3 53.0 62.2 50.0 50.5 77.4 26.3 9.4 41.7 45.9 82.0 95.7 22.5 17.7 36.8 83.0 68.4 90.1 73.9 39.8 21.8 88.1 80.2 44.3 44.1 54.1 49.3 77.8 35.9 72.1 31.1 33.3 29.1 33.6 49.6 25.5 17.9 24.1 145.6 15.3 104.7 35.4 44.5 35.6 12.9 12.1 17.6 23.2 11.5 14.4 13.6 14.3 14.2 14.3 15.8 17.0 44.2 38.5 53.6 2.6 51.5 258.0 188.4 57.0 97.9 7.1 69.3 51.3 21.9 44.3 50.5 22.0 4.2 73.3 117.4 109.1 74.3 99.1 1.5 130.5 44.8 49.4 120.4 325.0 7.2 79.8 82.0 43.7 68.3 237.8 94.0 11.5 22.1 73.1 49.0 18.5 8.0 77.0 28.5 59.4 278.7 1.8 12.2 118.1 87.2 4.7 48.3 17.3 35.0 5.5 2.0 129.1 135.3 16.6 85.2 158.7 60.8 44.2 40.4 7.4 0.0 61.9 42.4 1.1 5.3 97.3 218.1 67.0 62.6 10.5 58.5 255.7 MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268015 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 261.9;tongue: 279.7" "Cell type enhanced" "Detected in many" "Adipocytes: 57.5;Alveolar cells type 2: 57.7;Cytotrophoblasts: 52.6;Endometrial stromal cells: 96.7;Granulosa cells: 100.7;Smooth muscle cells: 83.2;Theca cells: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 15.5" "Group enriched" "Detected in many" 5 "dendritic cells: 15.5;monocytes: 9.4" "Cell line enhanced" "Detected in many" "U-138 MG: 176.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA017205: AB_1858933" "unprognostic (2.90e-2)" "unprognostic (9.99e-3)" "unprognostic (4.63e-3)" "unprognostic (1.98e-1)" "unprognostic (7.63e-2)" "unprognostic (5.02e-2)" "unprognostic (2.34e-2)" "unprognostic (3.89e-3)" "unprognostic (2.83e-2)" "unprognostic (9.27e-2)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.41e-6)" "unprognostic (2.34e-1)" "unprognostic (1.86e-1)" "unprognostic (2.23e-1)" "unprognostic (1.19e-2)" 71.0 11.4 9.5 20.5 9.7 4.7 21.4 10.3 8.5 44.9 15.7 65.8 13.0 76.4 18.6 50.0 48.0 31.4 195.7 9.3 12.1 7.5 25.2 22.5 9.8 13.8 14.7 69.5 11.7 49.3 3.8 27.6 11.2 44.0 20.9 2.5 12.4 57.1 261.9 14.1 19.2 75.0 11.1 12.5 31.5 10.6 12.5 11.5 16.4 279.7 10.2 56.1 21.2 9.4 34.6 28.6 22.0 29.1 62.7 92.5 13.8 121.9 94.7 55.9 59.6 19.5 22.2 26.5 31.2 122.5 48.8 22.9 33.1 64.6 124.2 52.0 22.0 43.3 30.5 4.1 24.8 39.3 43.8 74.7 27.2 105.2 164.2 46.3 37.5 28.5 19.8 4.9 36.8 14.8 24.8 19.0 12.2 28.9 16.0 36.2 45.0 0.1 13.6 19.6 12.9 12.4 47.0 11.3 19.7 35.6 12.9 20.9 37.9 176.3 71.4 53.1 27.9 0.1 0.1 5.5 126.2 10.6 18.9 0.2 9.4 0.0 1.0 8.3 1.0 1.6 0.8 1.7 15.5 2.5 0.0 0.8 2.6 0.5 8.2 0.3 0.8 3.4 9.5 9.7 10.3 8.5 9.3 12.1 13.8 14.7 11.2 11.1 12.5 9.4 57.5 38.5 57.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 20.0 44.4 0.0 0.0 7.4 11.0 0.0 52.6 2.3 0.0 1.9 43.9 0.0 36.7 96.7 14.1 0.0 0.0 0.0 27.6 21.9 36.5 0.0 35.6 5.1 100.7 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 15.5 0.0 0.0 0.0 0.0 38.6 0.0 0.0 1.4 0.0 0.0 1.9 13.1 0.0 0.0 0.0 83.2 0.0 0.0 0.0 0.0 21.6 3.6 70.5 0.0 0.0 MAP4K5 "GCKR, KHS, KHS1" ENSG00000012983 "Mitogen-activated protein kinase kinase kinase kinase 5" Q9Y4K4 14 50418501-50561126 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 332.7;Oligodendrocytes: 707.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 66.7;eosinophil: 26.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 66.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036696, HPA078030" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane" "HPA036696: AB_10672362, HPA078030: " "unprognostic (1.39e-1)" "unprognostic (1.00e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (4.41e-2)" "unprognostic (1.43e-1)" "unprognostic (8.58e-3)" "unprognostic (4.13e-2)" "unprognostic (6.31e-2)" "unprognostic (2.24e-2)" "unprognostic (1.53e-3)" "unprognostic (7.34e-2)" "unprognostic (1.78e-2)" "unprognostic (3.71e-2)" "unprognostic (1.40e-1)" "unprognostic (9.58e-3)" "unprognostic (2.02e-2)" 20.5 12.8 16.2 13.2 31.1 22.1 22.2 20.7 21.5 30.6 3.9 20.8 13.1 33.4 12.9 20.5 19.0 21.5 10.9 18.3 23.9 11.9 10.0 17.1 12.4 28.4 22.0 32.4 14.2 14.8 11.8 19.8 24.8 17.9 16.6 18.6 18.0 21.1 12.3 28.5 14.7 24.7 17.6 15.7 16.8 7.9 23.8 11.6 17.0 14.2 13.2 20.2 23.8 58.1 51.7 15.2 36.5 31.5 33.0 34.5 35.6 59.2 53.0 39.4 34.9 19.3 35.2 35.3 34.3 54.6 20.9 36.1 34.3 31.9 59.7 29.4 24.8 21.7 27.1 17.5 27.9 19.6 33.0 25.2 25.7 34.8 36.1 63.0 52.6 31.7 20.8 22.5 58.6 19.4 26.6 18.7 17.7 16.6 29.5 31.8 55.4 13.5 39.2 39.5 11.7 26.5 33.5 23.0 23.4 29.3 25.8 14.7 53.8 50.9 35.7 35.2 28.2 16.3 18.0 23.6 19.2 13.5 37.2 66.7 2.8 26.3 6.7 3.3 3.8 6.1 4.2 5.9 3.0 9.7 4.4 4.6 1.0 10.1 2.2 4.9 1.0 1.9 16.2 31.1 20.7 21.5 18.3 23.9 28.4 22.0 24.8 17.6 23.8 58.1 40.5 41.7 20.8 135.2 29.9 70.0 42.9 21.4 56.3 56.7 32.6 26.5 10.5 30.0 27.4 27.6 47.9 11.4 30.6 27.5 19.6 29.5 3.7 25.7 52.2 40.4 23.4 46.7 144.2 20.9 19.5 50.1 43.8 49.1 29.8 37.8 38.6 9.0 8.1 33.7 144.1 16.4 8.2 12.3 24.8 3.7 42.6 25.1 23.2 101.2 18.3 19.5 18.6 332.7 707.2 25.9 20.2 51.1 27.0 57.4 10.9 12.0 25.6 33.1 13.1 49.7 41.7 10.6 14.1 54.9 86.1 6.6 31.5 22.4 18.6 61.7 MAP7D1 "FLJ10350, FLJ39022, PARCC1, RPRC1" ENSG00000116871 "MAP7 domain containing 1" Q3KQU3 1 36155579-36180849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 286.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028075 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "HPA028075: AB_10603778" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (5.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.52e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.49e-6)" "unprognostic (6.00e-3)" "unprognostic (2.05e-1)" "unprognostic (3.57e-2)" "unprognostic (1.88e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (8.56e-6)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (9.32e-3)" 67.9 23.2 41.7 41.5 60.7 36.2 47.1 50.7 52.2 38.9 0.4 84.1 18.9 50.0 3.9 48.8 34.8 28.8 122.4 40.8 43.5 21.8 7.7 53.2 25.0 74.7 58.2 24.8 14.7 12.5 36.5 24.0 78.4 39.5 9.4 13.0 33.5 28.2 286.0 71.6 31.4 34.0 23.3 33.5 39.3 12.6 67.3 22.6 33.1 106.5 17.6 62.1 41.2 96.2 104.8 60.3 92.7 58.9 55.6 41.9 68.3 102.3 102.8 105.4 92.5 33.9 104.6 43.8 85.7 93.5 57.7 112.3 38.3 139.1 34.4 74.9 34.4 29.7 42.5 13.2 87.3 44.0 73.3 73.4 38.6 142.6 87.8 81.5 72.9 59.8 29.1 65.3 59.3 21.0 81.6 37.2 84.7 14.7 33.5 83.8 68.4 41.5 53.0 35.7 35.7 68.6 58.7 32.3 79.6 49.7 21.6 30.9 138.3 123.6 94.4 105.5 140.6 64.4 20.6 52.5 105.8 29.7 75.9 0.1 0.4 0.4 0.3 0.2 0.4 0.0 0.2 0.2 0.2 0.1 0.5 0.2 1.4 0.1 0.1 0.2 0.1 0.0 41.7 60.7 50.7 52.2 40.8 43.5 74.7 58.2 78.4 23.3 67.3 96.2 40.6 44.8 14.4 12.1 26.5 143.1 147.3 18.4 47.8 35.4 44.0 26.3 172.6 17.2 17.9 23.9 10.4 48.3 58.2 39.9 17.6 43.3 36.9 32.1 38.6 46.7 10.1 16.2 17.4 27.4 111.3 48.0 29.6 60.1 12.7 56.3 30.7 9.7 69.9 48.8 35.1 14.9 10.2 40.6 125.3 77.1 30.7 65.1 32.0 9.4 35.9 32.3 75.2 9.5 62.3 66.1 29.2 47.8 53.2 98.5 63.0 14.3 10.0 39.8 19.7 51.6 55.8 17.6 16.1 62.7 141.8 130.2 59.8 17.0 19.5 157.6 MAP7D3 FLJ12649 ENSG00000129680 "MAP7 domain containing 3" Q8IWC1 X 136213220-136256482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 264.2;Late spermatids: 288.5;Spermatogonia: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035598, HPA058101" Approved Uncertain Centrosome,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Centrosome Cytosol "HPA035598: AB_10671108, HPA058101: AB_2683604" "unprognostic (2.89e-1)" "unprognostic (1.23e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (9.00e-5)" "unprognostic (8.83e-3)" "unprognostic (3.77e-3)" "unprognostic (4.16e-5)" "unprognostic (5.35e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" "unprognostic (4.20e-2)" "unprognostic (9.91e-2)" "prognostic unfavorable (7.91e-4)" "unprognostic (2.04e-1)" "unprognostic (1.01e-2)" "prognostic unfavorable (5.38e-5)" 18.1 4.5 1.4 5.8 1.5 5.0 11.4 1.2 1.8 7.4 2.9 8.3 2.2 9.7 6.1 6.1 13.2 6.0 8.7 1.2 1.7 3.7 4.1 5.9 6.6 1.8 1.6 16.8 2.1 5.8 4.7 7.1 2.0 3.7 3.3 1.5 3.0 4.1 11.5 4.5 5.6 8.8 1.5 6.3 5.0 15.8 1.8 5.3 8.2 9.1 5.0 7.7 6.4 1.9 33.6 11.8 8.7 15.0 19.3 20.1 12.1 31.6 17.4 25.3 34.6 11.7 16.5 17.3 50.0 27.9 26.8 15.7 25.6 16.9 33.5 15.9 25.6 10.3 18.0 0.0 21.0 25.2 10.2 41.1 9.5 26.0 32.0 14.2 20.0 28.1 9.0 26.1 18.8 20.9 30.4 10.2 12.4 8.1 0.3 29.5 23.5 8.4 0.8 5.1 6.1 13.0 18.4 6.7 11.4 14.5 0.1 11.5 60.3 26.9 15.5 34.6 40.6 17.8 22.7 19.3 18.5 42.3 13.0 6.6 3.5 1.1 5.2 4.2 6.5 7.5 4.9 5.8 4.4 6.4 5.2 4.1 0.7 6.6 7.9 4.6 3.8 2.9 1.4 1.5 1.2 1.8 1.2 1.7 1.8 1.6 2.0 1.5 1.8 1.9 36.6 16.0 6.7 4.2 18.5 7.1 7.2 15.4 14.8 0.7 5.1 9.1 41.5 11.5 8.7 18.4 0.0 10.3 13.8 3.7 1.9 8.6 264.2 13.7 47.3 24.9 5.4 12.6 1.9 14.7 103.4 46.5 2.0 5.1 35.5 15.2 50.7 30.4 15.4 20.2 1.0 2.8 8.2 17.3 7.8 288.5 63.3 15.0 7.2 5.6 23.4 12.2 22.6 1.5 3.6 13.0 14.1 47.8 10.0 13.5 0.7 54.6 6.5 2.9 39.5 29.8 61.5 53.2 106.9 5.3 4.8 13.4 18.6 15.9 3.3 2.4 MARCHF4 "KIAA1399, MARCH-IV, MARCH4, RNF174" ENSG00000144583 "Membrane associated ring-CH-type finger 4" Q9P2E8 2 216257865-216372483 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 4.4;pituitary gland: 6.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 69.0;fHDF/TERT166: 43.8;TIME: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA014348 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA014348: AB_1853578" "unprognostic (4.84e-2)" "unprognostic (1.02e-4)" "unprognostic (1.63e-1)" "unprognostic (5.42e-2)" "unprognostic (3.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (6.49e-2)" "unprognostic (5.55e-3)" "unprognostic (1.07e-1)" "unprognostic (6.81e-5)" "unprognostic (4.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.23e-1)" "unprognostic (1.09e-3)" 0.0 0.7 2.6 0.0 3.9 0.0 0.0 0.0 4.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.6 0.0 0.0 3.1 2.2 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.4 0.0 6.2 0.6 1.1 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.2 0.0 2.7 0.0 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 12.5 2.5 0.0 0.0 0.2 1.6 0.0 69.0 23.2 14.5 5.1 0.1 1.0 0.0 10.5 43.8 24.2 0.1 0.0 26.7 14.1 0.0 0.0 5.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 13.3 19.6 9.3 19.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.4 1.9 0.1 0.0 0.0 2.2 0.0 0.0 32.7 22.7 23.9 0.1 18.6 0.0 0.0 0.0 5.2 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.9 0.0 4.4 3.1 2.2 0.5 4.1 1.1 2.7 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 120.0;heart muscle: 116.1;liver: 183.4" "Cell type enhanced" "Detected in some" "Astrocytes: 28.1;Cardiomyocytes: 38.1;Cholangiocytes: 20.0;Endometrial stromal cells: 30.6;Fibroblasts: 16.4;Hepatic stellate cells: 23.2;Hepatocytes: 65.8" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BJ: 133.3;BJ hTERT+: 498.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" No NA 8670000000 1900000000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" 6.3 3.6 9.4 1.3 9.4 0.0 2.8 12.9 7.0 120.0 4.9 57.5 1.9 88.4 3.3 11.1 17.7 5.1 116.1 10.4 27.0 4.8 183.4 6.0 1.0 19.2 16.5 2.7 0.2 0.3 1.0 9.0 15.3 46.0 5.6 0.0 2.3 52.2 37.5 6.3 7.5 44.4 22.2 0.8 1.6 0.5 14.6 0.2 3.2 18.9 4.3 9.9 61.5 32.0 0.0 0.0 0.3 0.4 15.7 17.3 0.1 133.3 498.3 1.8 0.9 0.0 0.0 0.1 0.0 40.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 2.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.2 0.0 0.0 5.4 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 9.4 12.9 7.0 10.4 27.0 19.2 16.5 15.3 22.2 14.6 32.0 1.1 0.0 1.8 28.1 0.2 2.9 0.1 0.2 0.0 0.0 0.0 0.0 38.1 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.9 0.7 30.6 2.0 0.0 0.0 0.2 0.0 0.3 16.4 0.0 0.7 0.0 0.2 23.2 65.8 0.4 0.0 0.9 0.0 0.0 1.9 3.7 7.5 2.5 0.3 1.8 1.0 0.0 0.0 0.0 10.1 0.2 0.0 0.0 0.7 0.1 0.1 0.0 2.4 0.0 0.0 0.0 5.4 4.5 0.0 0.0 0.2 1.7 0.1 0.5 5.1 0.0 0.1 MAST2 "KIAA0807, MAST205" ENSG00000086015 "Microtubule associated serine/threonine kinase 2" Q6P0Q8 1 45786987-46036122 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 170.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 66.9;Inhibitory neurons: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039722, HPA040155" Approved Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA039722: AB_10795294, HPA040155: AB_10793957" "unprognostic (7.80e-2)" "unprognostic (3.02e-2)" "unprognostic (5.77e-2)" "unprognostic (1.52e-1)" "unprognostic (3.82e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (4.31e-8)" "unprognostic (8.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (6.85e-13)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.90e-1)" 18.3 11.8 16.2 11.0 15.5 8.0 18.7 15.4 17.5 57.4 7.3 39.1 21.9 43.5 12.8 14.7 31.2 19.0 65.3 15.2 19.4 12.2 18.9 17.8 8.9 19.7 27.7 51.9 9.2 13.9 27.0 8.6 26.4 40.0 25.3 24.0 18.4 15.4 170.6 14.6 30.7 26.3 14.6 7.2 24.0 56.3 18.3 5.8 13.2 73.1 11.1 46.9 28.8 15.7 31.7 25.1 24.7 19.2 30.7 41.4 27.6 32.2 22.8 29.4 32.6 29.4 10.1 48.8 15.2 38.6 59.9 15.7 30.1 18.8 30.4 23.7 16.4 22.2 29.2 27.4 28.4 12.0 27.3 34.1 23.7 49.8 37.0 35.2 27.5 12.5 17.3 14.6 34.2 21.9 17.7 12.5 20.4 21.2 28.2 25.6 40.7 9.4 16.1 16.8 34.0 20.6 38.0 50.4 16.3 26.9 22.8 11.9 27.9 55.7 36.8 30.1 33.0 19.5 18.9 17.5 38.0 16.0 24.2 0.0 0.3 0.4 0.3 0.2 0.4 0.0 0.2 0.4 0.6 0.1 0.1 0.2 0.0 0.5 1.5 0.0 0.0 0.2 16.2 15.5 15.4 17.5 15.2 19.4 19.7 27.7 26.4 14.6 18.3 15.7 5.5 0.0 2.0 32.0 2.3 4.2 4.1 3.0 8.0 15.8 8.2 6.7 46.5 4.3 5.5 3.7 54.2 6.1 2.4 66.9 1.9 4.6 38.0 4.4 17.0 7.3 12.1 6.5 45.4 6.3 4.8 12.0 12.8 7.8 0.0 13.0 3.6 6.6 6.2 5.0 86.6 24.6 0.0 2.8 7.8 57.7 9.0 5.3 7.2 30.9 2.5 3.7 7.2 52.3 52.5 8.3 33.9 10.1 5.5 10.7 50.2 5.7 3.1 12.8 6.6 11.7 9.0 28.0 13.2 6.3 2.7 5.5 3.5 12.4 22.4 7.4 MBNL1 "EXP, EXP35, EXP40, EXP42, KIAA0428, MBNL" ENSG00000152601 "Muscleblind like splicing regulator 1" Q9NR56 3 152243828-152465780 "Disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 537.7;Oligodendrocytes: 471.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016398, HPA035098" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "CAB016398: AB_784435, HPA035098: AB_2674461" "unprognostic (5.46e-3)" "unprognostic (6.01e-3)" "unprognostic (1.94e-3)" "unprognostic (1.99e-1)" "unprognostic (3.44e-2)" "unprognostic (5.82e-3)" "unprognostic (2.75e-2)" "unprognostic (9.49e-3)" "unprognostic (5.18e-2)" "unprognostic (1.70e-2)" "unprognostic (2.78e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (7.53e-3)" "unprognostic (6.15e-2)" "unprognostic (1.77e-1)" "unprognostic (2.98e-1)" 116.4 35.8 18.2 105.0 24.9 90.4 48.1 22.9 22.3 76.9 18.9 69.0 43.6 68.0 30.1 65.3 38.4 75.2 63.2 18.7 23.0 31.5 47.6 78.1 138.4 25.5 20.1 45.1 24.3 26.5 11.8 29.9 26.0 55.1 71.1 17.7 32.3 66.0 188.8 61.5 58.3 116.5 25.0 92.3 40.5 14.9 25.2 108.4 31.8 131.0 135.1 78.4 32.7 32.5 133.8 107.8 17.3 38.9 132.5 135.8 12.7 163.3 131.5 105.6 87.8 48.0 76.3 136.3 81.3 230.8 32.8 59.7 32.1 94.5 155.0 106.9 43.7 149.3 52.2 22.7 73.8 180.5 104.5 63.8 50.2 121.9 94.0 80.8 219.5 54.1 77.3 180.5 103.6 45.9 169.0 66.0 7.2 38.9 85.4 170.5 53.0 171.6 53.7 66.3 13.8 15.7 71.1 38.2 69.8 6.2 53.1 270.5 186.6 143.6 55.1 96.4 142.7 186.9 115.9 154.6 83.8 220.6 79.1 95.3 53.7 90.1 79.4 61.7 84.4 56.2 64.5 66.5 70.1 49.7 80.6 70.7 78.4 79.6 54.7 24.9 62.6 104.3 18.2 24.9 22.9 22.3 18.7 23.0 25.5 20.1 26.0 25.0 25.2 32.5 175.5 150.6 193.7 179.2 252.1 213.6 49.0 25.9 156.0 28.5 51.8 48.0 179.8 52.9 89.5 38.6 64.6 26.1 266.0 164.7 21.5 36.0 2.6 64.0 92.2 142.9 47.3 160.2 258.6 63.6 9.2 122.9 78.0 68.5 162.6 31.5 90.0 91.5 60.9 32.0 185.5 68.8 14.2 216.4 195.5 9.7 89.5 235.0 103.2 537.7 249.4 18.2 230.7 224.7 471.9 57.3 90.3 71.5 181.3 61.2 121.4 42.2 63.1 84.1 98.6 102.7 145.6 4.3 12.7 149.4 243.6 14.8 340.1 46.8 80.7 50.1 MC4R ENSG00000166603 "Melanocortin 4 receptor" P32245 18 60371062-60372775 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 3.5;fallopian tube: 3.0;retina: 3.9" "Cell type enriched" "Detected in some" 7 "Bipolar cells: 7.3" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 70 "fHDF/TERT166: 94.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 10.2" HPA016719 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "HPA016719: AB_1853617" "unprognostic (2.29e-1)" "unprognostic (5.31e-3)" "unprognostic (5.78e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (3.33e-1)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (2.49e-2)" "unprognostic (2.30e-1)" "unprognostic (2.59e-1)" 0.0 0.2 2.2 0.0 2.4 0.0 0.2 0.1 1.7 0.0 0.0 0.0 0.1 0.0 0.3 0.0 3.0 0.0 0.0 1.8 3.5 0.0 0.0 0.0 0.0 1.0 1.5 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.1 2.7 0.3 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 94.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 0.1 1.7 1.8 3.5 1.0 1.5 0.7 0.4 2.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MC5R ENSG00000176136 "Melanocortin 5 receptor" P33032 18 13824149-13827323 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.4;lymphoid tissue: 1.0" "Cell type enriched" "Detected in single" 17 "Squamous epithelial cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-138 MG: 1.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA042365, HPA058088" Approved Supported "Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA042365: AB_2677961, HPA058088: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (7.10e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-1)" 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 MCF2 "ARHGEF21, DBL" ENSG00000101977 "MCF.2 cell line derived transforming sequence" P10911 X 139581770-139708227 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 29.5;seminal vesicle: 17.0;testis: 18.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 98.0;Excitatory neurons: 27.8;Inhibitory neurons: 36.2;Oligodendrocyte precursor cells: 20.6;Theca cells: 22.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "U-251 MG: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.42e-1)" "unprognostic (2.18e-2)" "unprognostic (1.46e-2)" "unprognostic (5.11e-4)" "unprognostic (8.95e-2)" "unprognostic (3.99e-2)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "unprognostic (1.80e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-2)" "unprognostic (7.77e-2)" "unprognostic (2.33e-3)" "unprognostic (3.68e-2)" "unprognostic (2.92e-2)" "unprognostic (4.62e-4)" "unprognostic (4.02e-2)" 0.2 29.5 5.8 0.4 4.5 0.7 0.1 6.4 8.8 0.0 1.7 0.1 0.0 0.1 12.3 0.0 0.8 0.7 1.0 4.4 7.0 1.5 0.2 0.1 0.6 9.1 7.4 10.2 0.2 0.0 3.4 0.0 9.7 1.2 0.0 9.2 1.0 17.0 0.1 0.1 0.3 0.0 5.5 1.1 0.2 18.6 14.1 0.5 1.1 0.2 0.1 0.2 0.1 5.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.5 3.1 0.0 0.5 0.6 2.5 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.3 0.6 37.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.8 4.5 6.4 8.8 4.4 7.0 9.1 7.4 9.7 5.5 14.1 5.9 0.2 0.0 0.0 3.6 0.3 0.1 0.3 0.2 0.6 2.2 0.6 0.4 1.8 0.0 0.0 0.0 98.0 0.0 0.3 0.1 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.0 27.8 0.0 0.0 0.7 0.0 0.1 0.0 2.2 0.4 0.2 0.1 0.0 36.2 0.0 0.0 0.6 0.3 2.5 1.2 0.2 0.0 4.7 1.4 1.0 4.1 20.6 7.6 0.1 0.0 8.2 0.1 0.4 0.0 0.6 0.0 2.4 0.0 0.1 0.4 0.6 0.8 0.1 0.0 0.0 0.3 22.8 0.0 0.2 MCFD2 "F5F8D, LMAN1IP, SDNSF" ENSG00000180398 "Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit" Q8NI22 2 46901870-46941855 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 253.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022410, HPA034593" Supported "Intracellular and membrane" NA NA 1200000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "CAB022410: , HPA034593: AB_2674239" "unprognostic (1.16e-2)" "unprognostic (5.71e-3)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (2.50e-1)" "unprognostic (2.87e-2)" "unprognostic (3.98e-2)" "unprognostic (3.10e-2)" "unprognostic (3.93e-2)" "unprognostic (8.32e-2)" "unprognostic (1.56e-3)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.64e-4)" 52.0 155.5 41.3 35.6 43.1 34.7 55.1 38.1 40.3 50.4 69.5 32.2 32.5 54.5 42.1 45.9 41.9 44.9 42.3 41.3 46.8 59.4 111.8 45.0 32.1 33.5 41.3 79.2 104.1 52.5 38.7 70.1 41.6 54.0 26.9 83.3 149.7 82.9 83.3 26.0 33.4 52.5 28.0 44.6 33.9 30.9 48.6 30.8 121.0 84.6 34.2 41.2 29.2 34.7 147.7 86.9 74.7 59.7 151.5 215.1 115.4 248.4 254.1 129.4 116.8 116.9 109.4 96.4 297.7 294.7 154.3 81.8 67.0 127.0 207.7 64.5 67.2 101.9 87.1 182.5 236.5 94.8 158.6 163.2 77.8 206.7 178.7 247.9 210.8 28.0 199.3 56.0 266.8 48.7 56.9 67.6 63.9 102.3 84.1 68.3 133.2 106.7 80.3 59.3 23.9 62.2 93.1 46.9 116.0 86.3 33.1 80.6 341.1 298.3 130.5 97.0 164.2 42.0 43.8 76.4 320.2 88.0 100.8 27.2 21.4 29.7 9.6 23.3 12.2 12.5 10.9 10.2 18.4 12.8 14.3 9.8 12.0 9.9 18.3 16.9 9.7 14.0 41.3 43.1 38.1 40.3 41.3 46.8 33.5 41.3 41.6 28.0 48.6 34.7 50.8 105.8 89.1 16.6 29.6 48.2 56.5 65.3 36.5 69.3 64.4 48.5 70.3 38.6 68.8 47.8 39.6 75.5 25.4 26.6 21.5 88.6 144.3 76.4 60.2 64.7 26.8 28.2 19.6 178.5 64.5 70.1 20.4 69.9 50.5 44.1 53.9 155.1 54.5 38.7 23.8 28.5 18.3 40.5 31.3 113.7 62.7 39.2 12.4 7.5 33.8 253.2 12.3 16.1 16.2 152.7 23.1 59.5 43.8 82.4 42.2 41.3 69.6 51.3 65.7 63.9 55.4 48.9 32.6 39.6 44.9 102.1 23.4 74.3 22.8 75.8 MEIS1 ENSG00000143995 "Meis homeobox 1" O00470 2 66433452-66573869 "Disease related genes, Predicted intracellular proteins, Transcription factors" Transcription "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.5;Endometrial stromal cells: 117.2;Horizontal cells: 82.4;Oligodendrocytes: 227.5;Rod photoreceptor cells: 121.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.6;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 43.5;HeLa: 29.3;HHSteC: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011521, HPA056000, HPA058641" Approved Supported Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 51: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "CAB011521: AB_776272, HPA056000: AB_2683004, HPA058641: AB_2683784" "unprognostic (6.84e-2)" "unprognostic (1.08e-1)" "unprognostic (3.43e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-1)" "prognostic favorable (2.70e-5)" "unprognostic (2.45e-2)" "unprognostic (7.78e-3)" "unprognostic (2.36e-2)" "unprognostic (5.91e-2)" "unprognostic (1.07e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (6.52e-2)" "unprognostic (9.71e-2)" "unprognostic (4.13e-2)" "unprognostic (2.01e-2)" 21.8 52.0 7.0 12.0 10.4 2.5 13.1 33.1 8.7 89.8 4.0 72.2 5.7 84.0 23.0 23.0 82.7 15.7 13.8 4.1 8.0 9.5 3.8 34.1 2.3 14.0 10.5 43.6 45.0 6.9 1.6 15.3 18.1 33.8 12.2 43.0 39.0 35.4 5.6 11.7 19.7 50.0 11.3 18.4 31.7 2.9 8.8 4.7 5.8 3.4 6.9 39.2 55.9 19.4 0.3 1.6 12.4 2.7 16.3 10.9 1.6 17.0 43.5 14.4 15.2 1.5 12.3 0.0 4.2 13.5 0.8 2.0 7.7 7.5 14.1 0.0 6.9 20.3 29.3 3.1 31.3 0.0 5.8 9.6 8.8 6.0 2.4 11.5 6.7 3.3 1.8 0.0 0.6 0.7 1.8 0.4 0.3 1.6 1.8 0.0 3.3 3.6 1.2 4.0 3.8 26.2 3.0 1.0 1.3 9.4 1.3 2.5 2.1 3.1 4.8 2.3 4.8 3.4 1.1 0.1 2.3 18.2 0.8 0.8 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.5 1.6 0.0 1.3 0.1 2.1 7.0 10.4 33.1 8.7 4.1 8.0 14.0 10.5 18.1 11.3 8.8 19.4 0.6 0.0 0.5 55.5 0.2 3.2 11.9 10.1 15.4 19.8 2.5 1.4 18.7 1.5 8.3 0.0 110.5 5.7 0.4 2.1 0.0 21.6 10.3 36.8 117.2 4.4 1.2 5.9 6.5 17.5 1.6 19.4 7.1 27.9 0.0 0.2 16.1 1.8 2.2 82.4 5.8 0.7 10.2 1.4 1.9 14.1 34.5 10.3 3.6 15.9 0.5 21.4 1.0 54.3 227.5 20.1 67.3 28.2 0.0 2.4 0.6 3.2 6.8 121.0 19.7 6.7 12.5 2.7 2.0 17.9 2.3 1.9 2.0 6.3 1.2 18.8 MEIS3 "DKFZp547H236, MRG2" ENSG00000105419 "Meis homeobox 3" Q99687 19 47403124-47419527 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.3;endometrium 1: 77.3" "Cell type enhanced" "Detected in many" "Early spermatids: 22.4;Endometrial stromal cells: 23.5;Excitatory neurons: 39.1;Horizontal cells: 45.4;Late spermatids: 57.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 76.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046699 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA046699: AB_2616456" "unprognostic (3.27e-3)" "unprognostic (2.98e-1)" "unprognostic (2.13e-2)" "unprognostic (4.49e-1)" "unprognostic (3.16e-1)" "unprognostic (4.67e-2)" "unprognostic (2.12e-2)" "unprognostic (5.93e-3)" "unprognostic (1.21e-1)" "unprognostic (2.73e-2)" "unprognostic (1.58e-2)" "unprognostic (9.76e-2)" "prognostic unfavorable (1.78e-6)" "unprognostic (9.29e-3)" "unprognostic (9.21e-3)" "unprognostic (4.36e-2)" "unprognostic (3.80e-3)" 13.1 6.9 68.8 9.0 64.3 0.0 16.3 20.5 102.3 41.7 15.7 18.7 6.6 77.3 2.3 10.8 51.8 11.2 10.2 69.2 50.4 7.5 2.0 8.1 2.9 19.8 22.4 21.8 4.2 6.6 17.2 13.7 21.6 18.9 3.9 8.0 6.9 10.9 2.5 6.0 14.1 38.9 16.3 6.7 6.3 12.2 36.4 1.2 6.2 2.7 1.6 17.1 15.7 46.8 1.0 33.4 76.3 0.3 42.0 36.4 1.3 33.1 53.8 27.5 47.5 3.0 5.3 0.3 3.8 58.2 22.6 3.8 8.1 9.6 8.8 50.4 11.3 0.0 12.7 0.3 26.4 0.6 65.0 26.5 1.9 10.5 5.6 9.5 0.0 0.0 0.8 7.7 3.0 32.2 0.0 0.4 22.1 1.0 1.9 0.1 5.8 0.8 1.8 2.4 3.1 59.9 29.3 2.6 14.4 30.5 1.8 9.8 0.0 20.2 49.3 15.1 4.7 0.1 0.0 0.1 56.3 3.2 41.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.8 64.3 20.5 102.3 69.2 50.4 19.8 22.4 21.6 16.3 36.4 46.8 1.7 0.0 3.2 2.3 0.0 0.8 1.2 0.6 0.0 10.0 8.7 4.6 1.4 0.0 1.9 3.7 6.2 0.2 0.1 0.0 0.0 0.1 22.4 0.7 23.5 0.9 0.0 0.0 39.1 0.0 0.4 11.1 0.5 1.6 0.0 0.3 1.4 0.1 0.7 45.4 11.2 0.0 0.0 0.0 1.9 57.4 11.5 0.4 7.2 4.7 0.0 17.0 0.0 13.0 2.0 0.1 0.0 4.1 0.3 4.0 0.0 0.0 1.5 2.9 13.1 0.9 11.8 3.1 4.8 0.1 1.0 0.8 1.2 0.9 0.0 0.9 MGLL "HU-K5, MAGL, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-128052190 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 565.4;Distal enterocytes: 398.7;Pancreatic endocrine cells: 535.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 84.7;plasmacytoid DC: 89.8" "Group enriched" "Detected in all" 14 "dendritic cells: 89.8;granulocytes: 36.0;monocytes: 84.7" "Cell line enhanced" "Detected in many" "BJ: 209.1;BJ hTERT+: 238.6;LHCN-M2: 191.3;RPTEC TERT1: 170.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011348, HPA011993, HPA011994" Enhanced Enhanced Nucleoplasm NA NA 100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA011348: AB_2668490, HPA011993: AB_1853914, HPA011994: AB_1853916" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" "unprognostic (8.19e-2)" "unprognostic (1.15e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.83e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (2.51e-1)" "unprognostic (2.11e-3)" 174.8 16.1 100.8 22.9 91.0 18.9 92.0 87.2 123.4 26.8 48.0 81.9 36.9 17.7 9.9 139.9 34.3 44.8 101.9 96.9 75.9 71.0 106.9 72.0 13.5 72.5 86.6 6.1 7.8 3.6 12.5 41.6 70.9 25.8 60.4 6.2 102.1 27.5 66.0 38.1 50.3 27.8 63.0 44.9 38.2 6.2 107.2 10.0 18.9 64.9 21.3 42.5 39.4 88.6 52.4 46.2 0.1 0.5 76.8 90.0 6.2 209.1 238.6 45.3 72.2 1.2 21.0 14.0 56.9 71.3 13.7 2.1 0.4 27.9 25.2 23.5 0.9 1.6 31.4 0.4 27.7 0.3 1.7 34.2 16.1 85.0 92.4 25.6 97.5 1.0 0.3 3.0 191.3 5.6 0.5 0.9 0.5 33.6 71.5 0.2 24.6 109.4 170.4 5.9 26.5 2.1 36.3 70.4 12.6 2.0 3.5 2.1 125.9 49.5 14.8 121.0 29.1 0.5 0.4 43.4 102.4 3.4 156.6 20.6 8.3 36.0 0.5 84.7 2.8 4.9 0.5 1.1 9.2 0.5 0.2 0.2 1.5 2.0 57.2 89.8 0.0 17.1 100.8 91.0 87.2 123.4 96.9 75.9 72.5 86.6 70.9 63.0 107.2 88.6 565.4 195.5 108.6 83.2 8.5 22.8 11.9 14.1 5.7 22.8 25.2 19.9 53.7 118.7 32.2 42.3 0.0 84.6 16.1 398.7 168.3 99.4 4.1 100.0 36.4 207.7 88.6 30.7 39.0 160.7 154.6 71.5 47.9 132.1 8.8 0.1 17.2 148.7 123.9 0.0 48.9 239.1 63.1 32.8 86.3 5.8 32.6 77.8 21.4 52.5 235.2 54.5 2.1 43.2 5.8 535.2 201.0 69.6 36.2 18.5 134.2 102.0 48.0 7.8 85.5 22.3 141.4 0.7 1.7 64.7 22.3 72.7 9.3 1.1 74.0 6.0 MICAL2 KIAA0750 ENSG00000133816 "Microtubule associated monooxygenase, calponin and LIM domain containing 2" O94851 11 12094008-12359144 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 193.5;Inhibitory neurons: 108.8;Late spermatids: 192.7;Peritubular cells: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 8.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-138 MG: 109.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030437, HPA039895, HPA040438" Approved Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Cytosol" "Nucleoplasm, Plasma membrane" "HPA030437: AB_10601873, HPA039895: AB_2676731, HPA040438: AB_10672896" "unprognostic (2.68e-2)" "unprognostic (1.77e-2)" "unprognostic (5.77e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (6.88e-4)" "unprognostic (2.20e-2)" "unprognostic (3.60e-2)" "unprognostic (9.32e-2)" "unprognostic (2.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.15e-2)" "unprognostic (6.47e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (4.61e-2)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" "unprognostic (1.67e-1)" 4.7 3.8 13.9 12.2 13.6 11.6 2.5 61.6 38.1 6.9 42.6 18.8 9.8 12.3 7.2 18.6 7.4 10.0 42.2 37.8 0.0 2.3 2.9 17.5 3.3 0.0 0.0 3.9 4.1 1.0 0.2 7.3 0.0 2.9 16.3 4.0 0.8 9.6 16.8 14.0 10.8 30.8 0.0 3.3 6.7 32.5 0.0 1.9 6.1 4.1 2.5 12.4 0.3 19.9 29.1 9.7 0.4 2.7 2.3 6.8 14.2 32.1 53.7 16.2 28.3 24.3 23.3 0.2 8.4 25.3 47.7 25.0 4.0 65.1 41.6 35.9 4.8 27.5 4.1 0.9 12.8 5.3 2.7 12.7 11.1 76.0 54.6 25.3 46.9 1.6 43.5 0.8 22.9 1.2 0.3 1.6 1.2 13.6 9.8 0.3 15.2 14.2 2.1 35.5 14.3 0.8 8.6 38.6 2.9 9.9 4.5 2.3 42.6 109.6 35.0 17.4 39.6 0.9 2.6 1.5 64.3 5.2 1.4 0.1 4.2 0.5 1.3 0.7 1.5 0.1 0.8 0.4 3.4 0.2 0.0 0.4 8.9 2.2 0.4 0.9 0.7 1.5 13.9 13.6 61.6 38.1 37.8 0.0 0.0 0.0 0.0 0.0 0.0 19.9 3.2 41.7 37.1 7.2 1.2 10.1 11.8 4.5 4.0 5.7 4.2 5.3 32.2 7.2 8.5 3.7 0.0 2.6 11.2 66.5 0.0 10.2 74.4 7.8 8.9 9.2 22.6 35.6 193.5 14.3 12.6 9.0 12.2 11.4 1.3 1.4 12.8 19.6 3.4 0.0 108.8 10.6 6.1 10.1 5.6 192.7 21.1 11.1 5.4 4.7 21.6 0.5 8.2 6.6 17.5 42.5 24.0 112.8 2.1 8.9 18.3 0.9 5.5 1.6 13.1 1.9 29.4 1.2 1.3 1.7 9.5 2.3 10.8 0.7 14.5 11.9 MINAR1 "KIAA1024, UBTOR" ENSG00000169330 "Membrane integral NOTCH2 associated receptor 1" Q9UPX6 15 79432336-79472304 "Predicted membrane proteins" Angiogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 10.3;brain: 4.7;retina: 6.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "melanoma: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-138 MG: 8.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011545 Uncertain Approved "Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Golgi apparatus" "HPA011545: AB_1852361" "unprognostic (5.45e-5)" "unprognostic (3.26e-1)" "unprognostic (4.56e-3)" "unprognostic (2.12e-2)" "unprognostic (1.74e-1)" "unprognostic (6.82e-2)" "unprognostic (4.49e-2)" "unprognostic (5.66e-2)" "unprognostic (2.90e-1)" "unprognostic (3.16e-1)" "unprognostic (1.96e-1)" "unprognostic (4.45e-2)" "unprognostic (6.66e-13)" "unprognostic (7.08e-2)" "unprognostic (2.73e-2)" "unprognostic (3.19e-3)" "unprognostic (1.19e-1)" 0.1 10.3 1.0 0.1 0.8 0.4 0.3 4.7 0.7 0.3 0.2 0.2 0.0 0.2 0.3 0.2 0.1 0.3 0.1 0.6 1.6 0.1 0.0 0.1 0.4 3.2 3.5 0.1 2.1 0.0 0.7 0.2 3.4 0.7 0.2 6.8 2.8 0.1 0.1 0.2 0.2 0.1 1.5 0.3 0.3 0.2 1.8 0.2 0.2 0.0 0.2 0.1 0.2 1.1 0.3 0.2 0.4 0.5 1.1 0.9 0.4 0.5 0.8 0.4 0.4 0.0 0.3 0.7 0.1 0.8 0.5 0.2 0.9 0.1 0.3 0.8 1.0 1.9 0.5 0.0 0.6 2.7 0.9 0.4 0.2 0.7 0.1 0.8 0.4 0.8 0.1 0.0 0.1 0.0 0.3 1.0 0.4 0.4 0.4 0.4 0.1 0.4 0.1 0.0 1.8 1.0 0.2 1.6 1.0 0.7 0.2 1.3 0.3 8.7 0.3 0.0 1.9 1.1 1.4 0.3 0.9 1.5 1.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.8 4.7 0.7 0.6 1.6 3.2 3.5 3.4 1.5 1.8 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MKX "C10orf48, IRXL1, MGC39616" ENSG00000150051 "Mohawk homeobox" Q8IYA7 10 27672874-27746060 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 11.1;prostate: 15.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 39.1;Granulosa cells: 11.1;Inhibitory neurons: 15.7;Peritubular cells: 7.2;Respiratory ciliated cells: 7.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 51.3;BJ hTERT+: 29.4;BJ hTERT+ SV40 Large T+: 33.1;BJ hTERT+ SV40 Large T+ RasG12V: 22.6;fHDF/TERT166: 148.4;SiHa: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA006927 Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear speckles" "HPA006927: AB_1853981" "unprognostic (2.04e-1)" "unprognostic (2.59e-2)" "unprognostic (1.17e-1)" "unprognostic (3.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.23e-2)" "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (8.37e-2)" "unprognostic (2.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.41e-1)" "unprognostic (1.09e-2)" "unprognostic (7.62e-2)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (6.38e-3)" 2.7 2.2 1.1 0.7 1.5 0.0 1.1 5.1 8.5 2.8 0.0 3.3 0.2 1.2 2.3 1.0 5.2 1.3 0.4 1.0 3.9 0.2 1.2 0.7 0.2 5.0 3.8 11.1 0.5 1.3 4.9 0.0 4.9 15.7 0.9 0.3 0.3 5.3 0.3 0.6 0.3 0.6 4.4 0.4 2.0 0.8 0.9 0.0 3.3 0.0 0.0 4.2 0.9 3.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 51.3 29.4 33.1 22.6 0.2 0.1 0.0 0.1 148.4 1.3 0.0 0.4 0.0 8.8 0.0 3.3 0.0 9.1 0.1 1.3 0.0 0.0 1.4 2.2 0.0 0.1 0.0 0.0 3.3 0.0 6.3 0.8 0.0 0.2 0.0 0.7 0.0 4.3 0.0 0.7 0.0 0.0 0.0 0.5 0.0 21.4 0.0 0.0 0.2 3.6 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.5 5.1 8.5 1.0 3.9 5.0 3.8 4.9 4.4 0.9 3.6 0.0 0.0 1.9 4.6 0.1 0.0 0.0 0.2 0.6 0.3 0.0 0.1 1.9 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.5 0.1 0.1 0.0 0.0 39.1 0.2 0.0 2.2 0.0 0.1 0.0 11.1 0.0 0.8 0.0 0.0 15.7 0.0 0.0 0.0 0.8 2.1 0.0 0.0 0.0 3.7 0.0 0.2 0.0 0.5 1.2 0.1 0.0 7.2 0.1 0.1 0.0 0.1 7.3 0.1 0.0 0.0 1.0 0.1 0.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770502-102780628 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "endometrium 1: 265.4" "Cell type enriched" "Detected in some" 38 "Basal respiratory cells: 3913.2" "Group enriched" "Detected in many" 4 "cervical cancer: 47.8;head and neck cancer: 102.2;lung cancer: 42.3" "Region enhanced" "Detected in single" "thalamus: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 11.8;HUVEC TERT2: 15.1;SCLC-21H: 4.7" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 765000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB002159: AB_564103" "unprognostic (8.76e-2)" "unprognostic (3.38e-1)" "unprognostic (1.98e-3)" "unprognostic (2.72e-3)" "unprognostic (7.17e-3)" "unprognostic (1.52e-2)" "unprognostic (5.67e-8)" "unprognostic (2.08e-3)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (1.67e-2)" "unprognostic (2.67e-1)" "unprognostic (6.99e-5)" "unprognostic (2.66e-2)" "unprognostic (7.98e-2)" "unprognostic (5.46e-2)" "prognostic favorable (7.12e-4)" 0.1 0.0 0.1 7.7 0.0 0.1 0.1 0.0 0.8 1.2 0.0 0.4 1.1 265.4 0.0 0.2 0.0 1.3 0.0 0.2 0.3 0.1 1.0 2.0 0.1 0.1 0.3 0.2 0.2 0.0 0.0 1.3 0.3 1.4 0.2 0.0 1.6 0.0 0.0 0.1 0.8 0.2 0.0 0.0 2.9 0.5 1.9 0.6 0.0 0.2 0.7 4.4 3.2 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.2 11.8 0.6 0.1 0.1 0.3 0.0 0.0 3.3 1.8 0.2 2.7 0.0 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.5 0.0 15.1 0.0 0.7 0.0 0.0 0.0 0.0 0.3 2.8 0.5 1.6 0.0 0.0 0.0 0.0 0.6 4.7 0.0 2.4 0.0 0.0 0.8 0.0 0.0 1.9 3.5 1.2 0.4 0.5 0.0 0.0 0.1 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.2 0.3 0.1 0.3 0.3 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.8 51.3 3913.2 0.0 0.0 0.7 0.0 0.1 0.0 85.4 29.5 0.0 0.0 0.0 0.4 0.0 34.0 6.1 6.4 2.5 9.0 0.0 0.0 0.0 14.6 0.0 6.3 0.0 12.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 9.5 1.3 0.0 0.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 102.5 0.1 0.0 0.0 42.5 0.0 0.1 29.3 0.0 0.0 0.0 11.7 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 8.2 MMP12 HME ENSG00000262406 "Matrix metallopeptidase 12" P39900 11 102862736-102874982 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.7;lymphoid tissue: 40.4;urinary bladder: 16.0" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 303.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "BJ: 3.3;fHDF/TERT166: 11.4;hTEC/SVTERT24-B: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.69e-2)" "unprognostic (7.31e-2)" "unprognostic (1.52e-2)" "unprognostic (1.52e-3)" "unprognostic (5.45e-2)" "unprognostic (3.05e-6)" "unprognostic (1.08e-2)" "unprognostic (4.66e-2)" "unprognostic (1.73e-1)" "unprognostic (6.92e-2)" 0.5 0.0 0.0 40.4 0.1 0.0 0.4 0.0 0.0 0.1 0.0 13.5 6.8 0.6 0.0 0.4 0.0 2.6 0.0 0.0 0.3 0.9 0.1 0.6 7.0 0.1 0.1 0.0 0.1 0.0 0.0 7.4 0.1 1.3 15.7 0.0 2.4 0.0 0.0 0.5 7.8 2.2 0.1 3.7 3.5 0.0 0.1 3.9 0.0 0.0 19.4 16.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 11.4 0.1 0.4 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 3.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 18.6 303.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.5 0.1 0.0 0.0 2.2 MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843609 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.7;salivary gland: 286.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 20.4;Basal respiratory cells: 25.8;Early spermatids: 24.2;Extravillous trophoblasts: 13.4;Fibroblasts: 17.9;Prostatic glandular cells: 11.9;Smooth muscle cells: 10.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Region enriched" "Detected in some" 4 "thalamus: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "BJ: 1545.7;BJ hTERT+: 4229.3;fHDF/TERT166: 1846.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 3.2" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA 2540000 460000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" 90.7 0.1 0.3 20.1 0.4 0.0 36.6 0.2 1.6 0.3 0.1 6.1 2.4 38.1 0.2 0.8 0.2 1.9 0.2 0.4 1.6 0.4 1.6 0.3 0.0 0.4 0.4 0.1 0.3 0.1 0.9 0.4 0.3 2.2 2.3 0.0 286.1 2.2 39.6 63.7 4.5 1.6 0.3 0.0 10.5 0.1 7.3 0.1 2.6 0.4 1.3 13.9 0.5 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1545.7 4229.3 27.0 8.7 0.1 0.2 0.0 0.0 1846.6 96.9 0.0 0.1 0.1 45.1 0.0 0.0 0.0 0.0 1.0 0.7 0.0 0.0 4.6 0.2 122.0 5.3 0.0 0.0 0.0 0.2 0.3 4.7 0.0 0.0 0.0 0.2 0.4 0.9 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.9 0.0 0.3 0.0 140.5 13.1 1.6 0.5 0.0 0.0 0.2 56.8 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.6 0.4 1.6 0.4 0.4 0.3 0.3 7.3 0.3 0.0 3.2 0.0 0.0 0.0 8.4 20.4 25.8 0.0 0.0 0.1 0.1 0.3 4.3 7.6 0.0 0.0 0.1 0.0 0.0 0.0 0.8 24.2 0.0 0.3 0.5 0.0 0.0 0.2 1.4 13.4 17.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.1 0.0 2.2 1.2 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.5 4.0 0.0 0.0 11.9 1.0 0.9 0.1 0.0 0.0 1.8 10.2 0.0 1.8 0.0 3.4 0.3 0.6 0.0 0.8 7.4 MRC2 "CD280, CLEC13E, ENDO180, KIAA0709" ENSG00000011028 "Mannose receptor C type 2" Q9UBG0 17 62627670-62693597 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 93.9;Endometrial stromal cells: 65.2;Fibroblasts: 141.6;Late spermatids: 82.8;Leydig cells: 71.7;Peritubular cells: 102.3;Theca cells: 71.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 210.9;fHDF/TERT166: 164.9;HSkMC: 148.6;hTERT-RPE1: 150.6;U-138 MG: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041991 Enhanced NA NA 36000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041991: AB_10794166" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (4.45e-2)" "unprognostic (2.59e-2)" "unprognostic (4.29e-2)" "unprognostic (2.67e-2)" "unprognostic (6.21e-2)" "unprognostic (1.80e-1)" "unprognostic (7.39e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (7.70e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (5.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" 24.5 8.6 4.8 13.7 7.9 5.3 16.2 5.6 5.3 39.3 22.5 12.3 6.6 31.3 9.6 21.2 26.3 32.4 45.2 4.3 5.1 18.1 2.8 35.0 4.5 9.3 9.1 45.8 7.5 1.2 17.4 9.6 8.9 25.7 3.2 0.7 9.0 20.8 12.2 28.8 10.9 21.3 9.9 16.3 9.0 16.2 6.0 4.5 7.0 6.5 2.0 17.9 28.2 11.2 0.1 35.1 23.3 29.7 64.1 115.4 3.1 210.9 138.8 34.3 40.8 2.1 0.4 0.0 15.2 164.9 15.1 17.8 4.0 19.0 8.8 26.7 5.4 17.6 27.2 0.0 97.2 22.9 0.2 148.6 9.5 29.6 3.4 150.6 15.4 10.6 9.3 0.0 47.8 6.3 6.6 70.6 4.9 0.0 2.4 22.3 15.4 0.2 3.2 0.4 2.9 52.2 14.1 0.4 0.3 14.3 0.6 97.1 68.5 216.6 83.9 36.2 43.6 0.2 0.0 0.0 66.8 22.6 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.8 7.9 5.6 5.3 4.3 5.1 9.3 9.1 8.9 9.9 6.0 11.2 8.6 3.2 35.9 5.9 0.4 11.3 5.8 20.7 25.0 11.1 1.6 11.4 4.4 0.0 2.3 1.8 0.0 0.7 0.6 0.1 0.0 0.3 93.9 22.6 65.2 5.2 0.0 28.4 3.3 0.2 2.7 141.6 2.0 2.9 2.5 13.8 5.3 0.0 6.8 0.0 0.9 0.1 0.0 9.2 11.1 82.8 71.7 7.0 5.4 57.1 0.6 0.8 1.0 3.5 0.9 0.6 0.0 102.3 0.3 2.1 0.0 0.0 1.4 0.6 0.0 31.4 23.3 11.7 9.3 34.6 7.7 1.9 2.7 71.0 0.2 1.4 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MTAP "c86fus, MSAP" ENSG00000099810 "Methylthioadenosine phosphorylase" Q13126 9 21802636-21937651 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046915, CAB080036, CAB080037" Approved Supported Nucleoplasm,Cytosol NA NA 3000000 "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "CAB080036: AB_11128130, CAB080037: AB_11129069, HPA046915: AB_2679862" "unprognostic (1.40e-2)" "unprognostic (1.83e-1)" "unprognostic (2.21e-1)" "unprognostic (2.58e-3)" "unprognostic (2.78e-1)" "unprognostic (6.16e-2)" "prognostic unfavorable (4.68e-4)" "unprognostic (9.47e-2)" "unprognostic (2.03e-1)" "unprognostic (8.63e-2)" "unprognostic (4.76e-3)" "unprognostic (4.27e-2)" "unprognostic (6.28e-3)" "unprognostic (2.18e-1)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-1)" 5.9 6.5 4.1 5.4 4.8 5.8 8.5 4.2 5.7 7.8 7.6 6.7 4.8 8.8 7.1 8.8 7.1 4.9 7.0 3.8 4.0 6.9 10.9 5.8 6.3 5.0 4.5 12.1 6.6 8.4 2.8 8.9 5.1 7.2 8.0 3.9 6.5 7.0 4.5 7.0 5.9 9.0 4.0 7.3 7.2 2.9 5.4 6.8 7.2 5.4 7.3 10.1 7.4 6.0 30.4 1.0 23.0 19.0 19.4 19.0 28.3 42.3 21.0 21.9 24.3 21.7 14.6 15.3 13.4 21.1 16.3 15.2 24.4 59.5 36.8 0.3 19.8 0.3 56.8 28.8 18.6 24.5 26.3 23.5 0.1 38.6 42.6 24.4 22.6 0.5 0.3 20.1 21.9 3.1 26.8 0.7 27.5 14.7 35.2 0.4 18.0 26.0 18.3 0.4 14.4 15.3 14.4 17.1 21.1 17.9 10.9 0.6 23.8 0.3 15.7 0.2 34.4 13.7 25.5 30.0 0.2 24.3 12.0 1.2 5.6 0.2 3.6 4.5 6.1 5.9 5.3 4.2 6.9 8.4 4.6 4.2 0.7 6.7 2.9 6.3 3.2 2.7 4.1 4.8 4.2 5.7 3.8 4.0 5.0 4.5 5.1 4.0 5.4 6.0 18.8 22.4 19.8 26.1 16.3 14.1 58.4 22.4 16.5 0.0 20.2 23.9 22.4 24.3 27.9 14.7 0.0 52.3 11.4 6.8 15.6 38.6 77.9 28.8 28.5 14.9 9.6 19.1 14.8 28.0 80.0 18.7 15.3 40.6 10.8 30.0 17.5 22.2 27.1 0.0 9.1 14.3 30.5 25.5 11.1 14.8 14.9 15.1 10.6 48.7 15.0 0.0 10.3 40.7 32.9 41.5 6.8 14.7 13.7 45.0 9.2 19.5 19.1 0.0 13.1 20.6 23.1 1.3 13.9 35.1 13.1 22.6 15.1 33.0 20.7 62.9 MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.5;Collecting duct cells: 31.3;Exocrine glandular cells: 60.7;Fibroblasts: 56.0;Pancreatic endocrine cells: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 31.4;BJ hTERT+: 125.8;fHDF/TERT166: 59.8;HaCaT: 52.4;HSkMC: 24.7" "Low region specificity" "Detected in all" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" NA NA 2600000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" 12.0 10.3 0.2 9.4 0.3 0.0 13.5 0.0 0.4 35.0 0.0 7.5 4.4 6.8 2.7 9.4 3.0 8.0 11.1 0.2 0.1 5.3 4.5 5.3 1.6 0.3 0.3 2.9 16.1 1.7 0.9 5.8 0.2 7.3 10.4 0.0 6.1 10.4 1.5 29.6 4.6 15.9 0.5 3.6 10.3 0.1 1.2 5.7 9.8 5.1 3.7 19.9 7.2 0.1 0.0 0.0 0.8 0.0 0.2 31.4 0.0 19.6 125.8 0.2 0.2 0.0 0.6 0.0 1.7 59.8 0.2 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.7 5.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.1 0.3 0.3 0.2 0.5 1.2 0.1 10.3 0.0 0.0 0.0 0.0 38.5 7.1 10.5 20.5 0.0 2.0 4.6 1.9 0.0 3.7 31.3 0.0 0.1 0.3 0.9 0.0 2.2 0.0 1.0 8.4 4.6 0.0 0.0 0.7 60.7 0.7 56.0 0.0 1.6 0.0 0.0 10.8 0.1 0.3 0.0 1.1 0.0 0.0 0.3 16.9 0.0 0.0 0.3 17.8 4.7 0.6 0.0 0.0 0.5 0.2 42.8 0.0 1.5 0.1 0.2 0.1 0.1 1.0 0.2 0.0 7.3 9.8 0.0 0.0 5.5 21.7 0.3 1.1 0.9 0.4 2.0 MXRA8 DKFZp586E2023 ENSG00000162576 "Matrix remodeling associated 8" Q9BRK3 1 1352689-1361777 "Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 149.5;Extravillous trophoblasts: 259.9;Fibroblasts: 183.3;Leydig cells: 176.1;Peritubular cells: 183.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "naive CD8 T-cell: 6.4" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 46.0;BJ: 143.6;BJ hTERT+: 66.9;fHDF/TERT166: 71.9;HSkMC: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053958, HPA055780" Uncertain Approved Nucleoli NA NA 760000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli "HPA053958: AB_2682322, HPA055780: AB_2682918" "unprognostic (1.39e-1)" "unprognostic (2.85e-1)" "unprognostic (7.31e-3)" "unprognostic (1.26e-2)" "unprognostic (1.94e-3)" "unprognostic (2.61e-1)" "unprognostic (6.75e-2)" "unprognostic (2.03e-1)" "unprognostic (4.22e-2)" "unprognostic (5.38e-2)" "unprognostic (2.97e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.43e-6)" "prognostic unfavorable (9.93e-4)" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.87e-4)" 103.6 11.7 2.9 8.2 2.5 0.6 70.0 1.1 2.9 100.4 1.7 58.2 6.3 117.2 2.6 17.6 57.4 19.4 42.8 4.0 2.4 26.4 7.4 53.9 2.5 5.9 4.5 81.9 8.7 1.1 21.7 11.6 2.6 39.0 1.7 0.8 32.4 11.4 16.6 41.6 29.5 6.4 2.3 26.4 28.9 14.7 3.2 0.6 46.6 5.0 0.8 52.8 59.3 3.0 4.1 0.8 1.2 1.0 16.5 46.0 42.3 143.6 66.9 16.6 19.9 8.0 3.3 1.7 0.6 71.9 0.1 3.0 1.0 0.0 3.2 3.2 1.3 1.2 3.1 12.8 43.4 0.2 1.6 54.8 0.0 6.2 0.0 32.4 0.0 0.9 17.3 1.4 21.5 0.4 0.4 0.5 14.0 0.3 4.7 0.6 0.3 0.4 0.0 0.7 3.2 8.9 0.5 1.4 0.1 10.4 11.1 0.7 1.3 0.7 23.1 21.8 0.6 3.3 0.3 0.2 5.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 6.4 0.0 0.0 0.0 0.0 0.0 0.2 2.9 2.5 1.1 2.9 4.0 2.4 5.9 4.5 2.6 2.3 3.2 3.0 22.2 3.2 0.0 7.5 0.5 10.7 1.1 0.7 2.2 0.7 7.0 47.9 3.5 0.0 0.0 9.2 0.0 9.5 1.1 0.0 0.0 5.7 1.7 4.3 149.5 5.1 0.0 0.0 0.3 0.0 259.9 183.3 2.6 3.7 0.0 0.5 6.4 0.1 9.3 0.0 0.4 0.0 0.0 0.0 19.7 11.4 176.1 1.7 10.6 6.5 0.7 50.7 0.0 0.0 0.1 1.1 0.0 183.6 1.4 0.6 0.0 1.4 0.0 1.5 13.1 65.8 74.7 0.7 5.4 1.3 10.5 29.4 2.2 0.8 0.0 0.3 MYADM ENSG00000179820 "Myeloid associated differentiation marker" Q96S97 19 53864763-53876435 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 207.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056301 Approved "Nuclear speckles" NA NA 27000 "Cluster 52: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "HPA056301: " "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (2.94e-1)" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.97e-2)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (7.71e-7)" "unprognostic (2.28e-3)" "unprognostic (1.29e-1)" "unprognostic (2.37e-2)" "unprognostic (6.14e-3)" 179.4 25.7 21.5 66.5 20.2 196.3 82.4 3.1 21.6 97.4 24.6 155.6 48.9 248.6 22.2 76.8 146.5 124.6 92.3 16.7 22.2 19.8 46.4 110.7 37.2 16.9 24.7 73.4 101.1 31.1 17.9 89.6 13.7 75.0 39.9 3.6 48.8 100.9 36.7 45.2 63.8 180.9 6.4 42.5 79.5 28.4 17.3 37.1 57.8 21.1 15.2 104.6 64.8 18.8 28.8 231.6 29.2 23.3 96.2 66.0 45.3 145.9 105.9 57.0 58.7 94.4 84.1 2.6 53.7 187.4 61.6 56.4 14.6 56.7 48.5 34.9 34.2 38.0 35.8 75.6 219.2 78.4 131.3 72.3 12.7 73.4 10.5 93.4 52.0 14.9 41.5 68.7 36.4 32.0 21.4 60.9 27.9 104.3 65.3 82.1 31.0 13.3 63.8 3.0 0.4 43.8 1.2 44.6 14.1 58.4 44.4 66.8 105.5 125.8 44.5 17.0 66.2 44.7 29.9 0.6 78.4 37.1 2.1 74.3 48.1 165.5 20.9 27.1 19.6 5.4 13.4 15.2 59.5 7.1 12.5 11.0 207.4 17.8 23.5 22.3 5.4 20.0 21.5 20.2 3.1 21.6 16.7 22.2 16.9 24.7 13.7 6.4 17.3 18.8 125.9 163.5 59.1 2.9 138.9 103.0 173.3 73.1 96.8 4.1 141.0 105.8 67.1 97.2 91.5 20.2 4.2 46.2 143.3 43.8 0.0 106.6 2.7 97.0 164.1 117.2 202.4 35.7 9.1 51.8 243.9 279.7 83.1 195.5 347.6 27.0 182.8 18.5 73.5 10.1 8.3 203.9 24.4 120.4 217.2 2.2 90.1 180.3 60.5 11.2 68.0 4.0 19.6 7.1 13.9 71.4 54.7 116.6 189.9 56.6 2.7 0.5 57.0 1.4 151.2 340.1 199.0 35.9 14.5 19.7 59.8 49.5 221.5 20.5 93.8 75.0 MYBL1 "A-myb, AMYB" ENSG00000185697 "MYB proto-oncogene like 1" P10243 8 66562175-66614247 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.1;testis: 11.8" "Group enriched" "Detected in many" 6 "dendritic cells: 127.3;NK-cells: 107.1;Plasma cells: 40.2;Spermatocytes: 35.8;T-cells: 89.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.9;MAIT T-cell: 1.3" "Lineage enhanced" "Detected in single" "T-cells: 1.9" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 82.5;BJ hTERT+ SV40 Large T+ RasG12V: 69.4;Daudi: 87.7;HBF TERT88: 113.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008791 Uncertain Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA008791: AB_1078540" "unprognostic (1.11e-1)" "unprognostic (2.47e-2)" "unprognostic (2.57e-1)" "unprognostic (7.23e-4)" "unprognostic (2.26e-1)" "unprognostic (1.89e-2)" "unprognostic (6.67e-3)" "unprognostic (2.38e-1)" "unprognostic (1.25e-1)" "unprognostic (3.78e-2)" "unprognostic (1.13e-2)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.03e-8)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (5.87e-2)" 1.0 0.7 1.1 6.1 2.2 2.5 1.7 2.0 1.7 0.7 0.3 1.0 1.3 1.1 0.5 0.7 0.8 2.3 3.4 1.0 1.3 0.4 2.0 2.3 20.1 2.9 1.7 0.6 0.2 0.4 0.4 0.9 3.2 1.2 1.4 5.9 0.5 1.6 0.9 1.2 1.9 2.3 1.9 7.6 1.3 11.8 1.6 2.5 0.6 0.8 16.1 1.1 0.8 3.7 35.4 11.9 3.7 10.1 1.0 2.1 2.6 47.7 21.8 82.5 69.4 1.6 34.9 87.7 4.2 40.4 31.0 10.0 3.5 4.0 113.0 10.6 5.5 1.8 13.4 1.6 0.2 0.8 3.4 0.7 0.4 22.7 19.0 14.8 2.7 6.4 0.4 28.3 51.0 3.1 5.8 1.3 2.8 3.3 15.8 1.9 14.1 2.2 19.4 1.2 8.2 3.3 8.4 3.0 8.6 5.6 50.6 2.3 14.5 49.4 11.3 11.1 44.2 8.2 12.1 25.7 13.0 5.3 20.0 0.0 0.0 0.0 1.9 0.0 1.3 0.0 0.3 0.8 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.1 1.1 2.2 2.0 1.7 1.0 1.3 2.9 1.7 3.2 1.9 1.6 3.7 3.0 0.0 2.3 3.3 4.0 1.8 0.4 0.3 1.8 10.4 4.7 6.6 9.1 2.8 0.1 0.0 2.1 2.0 127.3 0.5 0.0 0.5 3.9 0.8 2.4 1.7 0.0 6.6 3.9 0.0 0.7 2.7 3.1 1.4 0.0 5.6 4.2 0.9 0.7 5.0 2.7 0.4 0.0 1.6 3.2 4.2 0.9 5.1 1.8 8.4 1.6 10.3 107.1 5.5 12.4 0.2 1.1 0.0 40.2 0.3 0.0 0.5 1.5 9.1 0.0 2.5 4.5 35.8 6.8 3.2 0.4 1.5 89.1 1.4 0.8 0.3 MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281280-36387967 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 1343.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Nuclear bodies,Plasma membrane,Actin filaments,Cytosol" No No 410000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments" "Nuclear bodies, Cytosol" "CAB015386: AB_784698, HPA001644: AB_1079439, HPA064783: AB_2732721" "unprognostic (1.38e-1)" "unprognostic (9.12e-2)" "unprognostic (4.21e-2)" "unprognostic (6.34e-2)" "unprognostic (1.49e-1)" "unprognostic (3.90e-2)" "unprognostic (9.56e-2)" "unprognostic (8.28e-2)" "unprognostic (5.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (9.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.62e-1)" "unprognostic (2.59e-2)" 295.9 95.5 42.3 181.1 42.1 245.9 231.5 40.6 54.7 181.2 65.5 192.6 107.0 356.4 39.3 153.8 182.2 134.5 161.1 50.8 39.4 140.7 101.6 286.2 161.7 52.7 51.7 121.1 160.3 55.0 52.6 166.5 48.1 131.8 89.8 9.7 177.2 98.4 84.0 160.6 163.5 174.1 48.8 232.5 135.8 38.2 52.1 125.1 141.2 46.3 104.1 168.8 166.8 48.2 612.2 277.0 86.2 74.2 156.8 195.1 437.3 398.4 507.5 554.6 413.2 302.1 170.3 156.9 230.1 666.1 265.0 412.7 125.2 779.4 559.6 356.1 120.9 302.6 294.3 259.9 481.1 346.9 463.8 233.0 234.7 751.9 626.4 540.3 461.8 113.2 67.3 205.8 448.9 161.9 124.4 204.0 51.7 171.1 169.2 233.3 267.3 146.7 314.5 581.5 129.6 53.0 559.7 217.0 251.6 218.5 162.4 177.1 1343.7 1222.6 370.3 237.5 731.5 135.2 114.7 129.0 463.2 172.3 363.1 72.6 25.2 64.7 32.4 19.8 28.4 13.4 23.5 26.4 17.2 11.9 18.3 20.4 41.2 9.0 26.5 8.0 26.3 54.5 42.3 42.1 40.6 54.7 50.8 39.4 52.7 51.7 48.1 48.8 52.1 48.2 303.9 118.6 87.1 12.7 108.4 144.0 182.4 123.1 72.8 2.6 90.5 89.4 62.6 80.1 89.7 92.0 2.1 87.0 151.7 359.8 7.9 309.4 35.8 89.7 121.6 258.7 73.8 51.9 42.5 245.8 193.1 82.9 123.8 194.7 93.1 117.1 132.8 102.8 100.4 82.4 6.7 131.0 59.0 119.6 124.2 37.4 68.0 168.8 85.4 61.8 196.6 11.9 137.0 7.5 33.3 344.6 186.8 211.4 125.9 184.4 159.8 27.5 51.5 5.3 203.8 39.9 275.2 6.9 10.4 133.6 135.1 46.4 213.2 141.3 139.5 134.3 MYL12A "MLCB, MRCL3, MRLC3, MYL2B" ENSG00000101608 "Myosin light chain 12A" P19105 18 3247481-3256236 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 4234.5;skeletal muscle: 3072.7;tongue: 2082.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 6094.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004503, HPA039262, HPA045244, HPA059197" Supported NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB004503: AB_2282358, HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (2.14e-3)" "unprognostic (5.30e-2)" "unprognostic (1.80e-1)" "unprognostic (5.31e-2)" "unprognostic (3.03e-2)" "unprognostic (7.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.57e-3)" "unprognostic (2.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.49e-3)" "unprognostic (2.30e-1)" "unprognostic (9.86e-2)" "unprognostic (1.30e-1)" "unprognostic (4.98e-2)" "unprognostic (4.58e-3)" "unprognostic (7.13e-2)" 492.0 246.2 83.6 358.2 86.6 455.0 423.8 91.2 123.7 311.2 114.1 448.8 315.2 258.1 267.0 410.9 274.7 354.6 4234.5 81.0 97.2 427.9 462.3 564.8 562.8 101.2 89.5 191.4 228.8 364.4 106.9 445.4 101.7 247.4 486.6 50.7 282.4 245.6 3072.7 280.7 332.6 317.3 97.0 566.3 369.0 106.8 93.5 461.6 314.3 2082.4 601.6 408.3 240.5 96.8 467.6 298.1 580.7 257.3 701.6 691.8 386.7 1045.3 1176.5 827.9 895.4 440.7 543.5 224.6 263.9 1412.9 627.3 192.7 360.9 601.0 736.0 326.9 129.4 236.6 297.2 360.0 1118.3 658.7 401.0 1129.5 803.3 698.0 420.0 799.7 1332.7 272.6 292.6 694.7 1748.4 793.6 282.9 571.7 253.3 496.5 199.3 167.0 341.1 384.7 1827.8 680.1 86.7 211.5 840.9 333.1 674.0 541.8 233.8 918.2 1717.0 212.6 508.4 635.5 828.0 166.9 278.8 351.6 665.5 249.5 798.1 3164.3 1120.8 2382.2 2287.2 1192.8 2280.2 1588.6 2106.9 2315.1 1639.0 1353.6 1901.6 2215.8 1785.1 1629.3 1464.6 2487.8 2068.3 4517.7 83.6 86.6 91.2 123.7 81.0 97.2 101.2 89.5 101.7 97.0 93.5 96.8 1206.6 737.2 291.0 4.6 530.9 635.9 973.5 1804.3 259.6 29.4 294.8 396.4 6094.3 449.0 949.8 511.3 12.5 748.1 1090.0 1033.5 471.6 1335.5 32.4 570.0 312.1 938.8 105.4 244.9 1.7 1487.7 1168.6 453.0 318.5 662.3 521.0 301.7 870.6 272.5 844.2 57.2 2.9 570.4 889.0 605.3 992.8 32.8 334.6 924.2 442.9 26.2 1616.2 92.6 1388.3 4.0 9.0 2236.5 977.2 396.5 207.4 817.8 758.0 757.7 673.1 42.4 571.9 378.7 757.0 78.9 166.5 262.6 545.1 666.0 1078.8 303.7 429.6 698.2 MYL6 "ESMLC, MLC1SM, MLC3NM" ENSG00000092841 "Myosin light chain 6" P60660 12 56158346-56163496 "Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046859, HPA063034" Approved NA NA 60000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA046859: AB_2679842, HPA063034: AB_2684927" "unprognostic (1.10e-1)" "unprognostic (4.99e-2)" "unprognostic (1.89e-1)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" "unprognostic (1.89e-1)" "unprognostic (3.73e-2)" "unprognostic (3.53e-1)" "unprognostic (2.00e-1)" "unprognostic (3.51e-3)" "unprognostic (4.11e-2)" "unprognostic (2.04e-1)" "unprognostic (2.86e-2)" "unprognostic (8.33e-3)" "unprognostic (1.71e-1)" "unprognostic (7.90e-2)" "unprognostic (2.01e-1)" 2247.0 1427.5 830.7 1207.0 830.7 1756.5 1977.9 864.2 962.6 1767.3 901.0 5900.2 1027.9 2971.8 1635.0 1777.8 2197.9 905.8 1153.9 809.9 863.8 1915.8 1172.0 1946.7 882.9 900.5 874.9 1155.2 1032.8 1466.7 747.7 1441.7 869.2 2037.5 2360.3 927.1 1167.6 2912.2 411.1 1090.1 1867.5 4209.9 858.5 1547.8 2128.0 494.6 899.3 1151.3 1316.7 578.7 1404.7 3041.7 1685.0 869.9 1924.9 1739.1 3199.3 958.8 2063.5 2065.5 1755.8 4056.4 4162.8 5469.7 3191.3 2738.5 1720.0 735.0 2274.3 5778.4 1417.7 1222.8 1995.9 2846.0 3556.8 1423.1 666.5 1311.5 2481.7 1536.9 1512.2 913.8 2304.1 2389.9 2013.5 3242.3 1263.1 4706.8 4854.4 867.2 708.1 2121.5 4585.6 2052.1 1291.6 1402.8 1629.5 1071.6 1746.1 1027.3 1265.3 932.9 5125.1 2361.7 1169.2 862.9 4456.0 1380.0 760.4 2312.4 2148.7 2383.0 5212.3 1486.3 1011.6 2077.3 2746.8 635.3 1150.3 867.7 1953.3 1168.9 1578.1 11449.4 4509.8 13302.4 3191.2 5016.0 2404.9 2844.7 2828.6 2994.0 4747.3 2558.5 2020.7 2528.3 8440.7 2233.9 6531.2 5167.0 4209.8 14776.8 830.7 830.7 864.2 962.6 809.9 863.8 900.5 874.9 869.2 858.5 899.3 869.9 2044.5 1733.9 1161.8 16.0 704.4 2114.0 2470.4 2988.3 746.1 278.4 896.3 1394.8 672.8 946.5 2016.5 1475.0 316.9 1704.4 1144.5 2568.2 2406.5 4126.7 292.4 1134.2 1714.2 1628.1 1017.3 857.4 15.6 4820.4 2604.5 1264.0 871.6 1676.6 994.3 1307.8 1328.6 887.8 3370.3 80.8 19.8 1572.3 1845.3 1148.3 2472.8 910.7 1064.0 1872.2 1469.2 39.4 4426.3 820.8 1195.7 17.6 31.3 6222.1 2715.8 2775.1 892.8 1762.1 3007.9 2956.9 1870.9 763.7 1735.5 685.8 3305.2 76.2 115.0 1139.6 2066.1 1929.9 1191.9 1039.1 1406.1 2558.6 MYL9 "LC20, MLC2, MRLC1, MYRL2" ENSG00000101335 "Myosin light chain 9" P24844 20 36541497-36551447 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 8015.9" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 860.2;Cardiomyocytes: 1856.1;Peritubular cells: 1891.9;Sertoli cells: 2143.1;Smooth muscle cells: 2525.7;Theca cells: 881.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 783.3;BJ: 1047.3;fHDF/TERT166: 844.3;hTERT-RPE1: 645.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 76.1" "HPA039262, HPA045244, HPA059197" Supported NA NA 34000000 "Cluster 52: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (1.15e-1)" "unprognostic (5.05e-2)" "unprognostic (2.67e-3)" "unprognostic (5.38e-2)" "unprognostic (7.17e-2)" "unprognostic (5.06e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" "unprognostic (9.06e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (7.92e-7)" "unprognostic (1.90e-2)" "unprognostic (8.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.92e-2)" 944.6 948.6 61.6 347.0 76.7 5.2 649.5 63.3 132.2 1083.0 104.6 8015.9 270.5 2897.3 238.2 999.8 1643.3 364.3 2294.5 61.4 63.1 352.2 116.6 617.9 56.4 66.3 66.3 717.2 82.0 45.4 91.2 160.3 66.1 2347.4 345.8 22.8 200.7 2248.7 164.3 289.2 1287.7 2107.8 62.0 274.3 1946.4 260.7 66.5 27.4 431.7 111.4 23.2 4176.1 943.6 63.3 79.4 1.3 60.3 1.2 783.3 298.6 264.5 1047.3 450.9 541.3 349.9 612.3 9.1 0.2 535.6 844.3 120.6 29.4 0.2 2.4 125.7 0.9 0.2 16.7 114.4 57.3 500.4 0.4 17.7 420.8 54.4 359.9 1.6 645.9 19.2 0.0 2.4 28.0 461.7 0.2 0.3 7.8 24.0 16.1 5.6 0.4 0.0 5.8 4.6 5.8 0.6 4.1 11.1 26.6 0.6 257.5 232.9 15.6 137.0 510.9 220.1 75.5 1.0 0.8 4.0 2.3 194.3 0.8 0.6 0.0 0.1 2.2 0.0 0.0 0.0 0.9 0.0 0.1 0.3 0.2 0.0 0.0 1.9 0.2 0.0 0.4 0.0 7.2 61.6 76.7 63.3 132.2 61.4 63.1 66.3 66.3 66.1 62.0 66.5 63.3 325.3 394.2 52.3 0.0 6.6 60.7 320.2 167.1 21.6 1.4 36.8 860.2 1856.1 24.3 50.8 90.1 0.0 37.0 6.3 0.1 27.4 310.3 9.3 13.1 419.9 179.7 0.0 5.7 0.2 116.0 78.3 410.4 10.2 9.3 15.2 234.3 169.9 2.7 32.0 1.7 0.1 1.2 14.2 5.0 76.6 55.4 331.8 111.7 72.9 30.9 19.4 230.4 6.2 0.0 0.5 47.9 2.5 1891.9 6.4 156.9 105.5 42.1 31.8 6.1 2143.1 65.9 2525.7 16.3 9.5 6.5 53.4 26.8 14.7 881.1 2.0 61.9 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 1700.3;smooth muscle: 2137.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 728.5;Hepatocytes: 208.7;Peritubular cells: 690.5;Sertoli cells: 276.1;Smooth muscle cells: 448.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 200.0;BJ hTERT+: 298.2;fHDF/TERT166: 260.2;hTERT-RPE1: 202.7;RPTEC TERT1: 291.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 1500000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" 143.6 57.4 37.6 188.7 64.8 3.3 163.4 72.1 42.4 281.3 14.1 551.5 110.9 669.2 232.9 420.6 289.8 250.4 33.6 33.6 46.7 64.4 67.2 85.2 33.6 104.6 64.8 95.9 15.3 11.6 2.6 70.2 99.3 907.6 299.1 13.6 140.1 1700.3 10.0 20.1 125.1 2137.7 55.6 89.5 122.7 50.5 52.2 8.0 22.2 14.9 19.1 505.7 84.8 112.1 14.4 38.4 10.8 7.8 10.8 1.9 4.7 200.0 298.2 137.3 92.1 8.1 7.4 0.6 42.5 260.2 67.0 4.8 5.2 1.8 149.0 0.2 0.7 102.4 0.9 28.9 56.1 0.6 9.8 36.9 3.5 24.4 34.4 202.7 8.9 1.3 1.2 0.5 90.9 1.7 0.2 2.5 12.0 0.5 5.1 13.5 6.8 36.7 291.9 8.5 1.4 6.4 21.8 1.9 3.1 25.0 1.0 0.3 33.4 39.5 13.9 10.3 30.7 3.4 4.2 0.3 104.0 1.0 9.6 7.4 1.6 0.4 0.1 0.2 0.0 0.2 0.0 0.0 3.5 0.1 0.2 0.1 5.0 0.0 0.0 3.3 0.2 20.9 37.6 64.8 72.1 42.4 33.6 46.7 104.6 64.8 99.3 55.6 52.2 112.1 45.9 16.0 38.3 43.4 2.5 20.5 27.2 24.8 1.2 2.9 19.9 728.5 25.2 37.1 5.7 27.6 125.1 0.8 3.5 88.1 3.9 6.0 40.7 45.9 46.6 56.9 11.4 3.2 25.2 3.9 0.8 40.1 3.1 54.4 2.5 3.2 45.3 208.7 4.9 3.3 3.4 3.9 8.2 7.9 37.0 33.8 104.7 20.8 19.6 8.4 1.2 4.7 0.0 5.5 37.0 4.0 18.7 690.5 3.3 8.6 14.2 17.2 17.6 19.9 276.1 5.6 448.7 4.7 4.6 1.3 20.2 2.5 3.2 4.5 4.2 3.7 MYO1C myr2 ENSG00000197879 "Myosin IC" O00159 17 1464186-1492686 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001768, HPA005924, CAB037023" Enhanced Enhanced "Nuclear bodies,Plasma membrane" NA NA 3800000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Plasma membrane" "CAB037023: AB_477180, HPA001768: AB_1854252, HPA005924: AB_2667469" "unprognostic (3.60e-1)" "unprognostic (4.71e-3)" "unprognostic (2.89e-1)" "unprognostic (2.96e-3)" "unprognostic (1.38e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-2)" "unprognostic (1.99e-2)" "unprognostic (5.02e-2)" "unprognostic (4.66e-2)" "unprognostic (4.93e-2)" "unprognostic (3.47e-2)" 169.3 27.0 12.4 34.4 11.8 4.9 115.9 13.3 12.7 77.4 17.1 104.9 47.4 97.1 21.5 64.7 66.4 46.1 97.5 10.2 14.7 56.8 39.5 87.2 24.1 14.8 11.2 43.6 69.3 34.3 22.9 56.9 14.6 69.9 41.7 2.1 91.7 58.2 49.5 57.7 65.6 65.7 11.9 30.8 76.3 17.1 13.7 21.3 60.6 35.8 25.1 86.3 67.8 10.8 169.8 182.1 19.3 79.5 88.8 87.6 74.2 168.6 138.9 108.7 91.0 122.3 90.7 16.9 118.7 261.1 72.7 139.9 29.2 117.2 56.3 75.2 74.5 16.2 96.4 46.2 131.7 1.6 81.5 68.7 57.3 100.2 57.3 99.5 141.7 10.5 13.1 13.7 93.5 129.5 1.9 1.4 12.4 105.8 34.0 6.9 26.4 30.7 100.5 86.9 7.8 43.0 105.9 152.6 67.4 47.5 125.3 8.7 187.9 156.6 119.1 77.7 147.8 10.7 9.1 7.2 124.7 4.1 138.8 0.1 0.9 0.0 0.9 2.0 0.4 4.8 2.1 0.9 1.1 3.8 0.7 0.4 0.5 0.0 1.7 1.0 1.9 1.5 12.4 11.8 13.3 12.7 10.2 14.7 14.8 11.2 14.6 11.9 13.7 10.8 133.7 125.0 35.9 5.5 20.8 39.8 38.2 27.8 31.9 4.1 44.0 33.0 75.4 48.6 36.3 86.5 0.0 57.8 2.5 159.0 21.5 62.3 17.4 26.3 44.4 78.0 39.5 13.5 2.5 52.0 28.4 51.8 66.3 75.5 12.0 25.4 83.6 38.5 20.0 5.0 3.8 111.8 14.2 14.5 43.4 11.4 42.3 16.7 64.0 15.0 20.3 5.6 0.0 2.5 1.0 92.8 88.7 48.5 12.8 64.7 92.8 15.4 12.9 2.1 118.3 37.7 90.6 9.4 7.5 39.5 42.6 47.6 10.0 10.6 88.1 39.2 MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 47.3;Endometrial stromal cells: 48.5;Peritubular cells: 100.8;Sertoli cells: 26.3;Smooth muscle cells: 32.9" "Cancer enhanced" "Detected in some" "stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 6.5;BJ hTERT+: 6.4;HBF TERT88: 10.4;hTEC/SVTERT24-B: 11.7;REH: 8.4;SuSa: 12.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB046485: AB_10600720, HPA071528: , HPA072582: " "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-2)" "unprognostic (5.33e-2)" "unprognostic (2.15e-4)" "unprognostic (2.71e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (4.83e-2)" "unprognostic (1.01e-4)" "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.91e-2)" 3.2 1.0 0.4 4.3 0.7 0.0 1.2 0.3 0.8 9.4 1.6 24.2 2.6 13.0 2.4 13.1 8.5 4.6 14.2 0.4 0.4 0.7 0.2 2.7 0.1 0.5 0.5 4.4 0.3 0.1 0.2 3.4 0.8 8.8 4.9 0.0 0.2 20.7 0.5 1.3 5.1 15.8 0.5 0.6 6.1 2.1 0.8 0.1 0.7 0.8 0.1 17.2 4.4 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 6.4 2.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.8 0.4 0.4 0.5 0.5 0.8 0.5 0.8 0.4 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 47.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.0 48.5 1.2 7.8 0.0 1.2 0.2 0.1 3.6 0.0 1.0 0.0 8.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 1.0 0.5 0.6 0.2 0.0 9.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 100.8 0.0 0.1 0.0 0.1 0.0 0.0 26.3 0.2 32.9 0.3 0.8 0.1 0.9 0.5 0.4 6.0 0.0 0.1 MYPN MYOP ENSG00000138347 Myopalladin Q86TC9 10 68106117-68212017 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 64.1;skeletal muscle: 283.6;tongue: 172.8" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 114.2" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 0.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 1.4" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.4" "Cell line enhanced" "Detected in many" "BJ: 39.8;fHDF/TERT166: 112.3;HBF TERT88: 25.6;LHCN-M2: 47.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA036299, HPA061494" Enhanced Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 41: Basophils - Cellular respiration" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Vesicles" Cytosol "HPA036299: , HPA061494: AB_2684539" "unprognostic (4.75e-2)" "unprognostic (2.20e-1)" "unprognostic (8.14e-3)" "unprognostic (8.62e-3)" "unprognostic (3.91e-1)" "unprognostic (3.36e-3)" "unprognostic (4.62e-2)" "unprognostic (3.86e-2)" "unprognostic (2.82e-1)" "unprognostic (2.26e-3)" "unprognostic (3.94e-3)" "unprognostic (3.10e-1)" "unprognostic (2.88e-8)" "unprognostic (4.63e-5)" "unprognostic (9.94e-2)" "unprognostic (2.01e-1)" "unprognostic (3.47e-1)" 0.1 0.3 0.2 0.2 0.1 0.6 0.1 0.5 0.2 0.0 0.0 0.3 0.1 0.1 0.1 2.2 0.0 0.1 64.1 0.8 0.8 0.0 0.0 0.0 0.2 0.6 0.2 0.1 0.6 0.0 0.0 0.1 0.1 1.7 0.1 1.7 2.7 0.0 283.6 0.1 0.1 0.2 0.0 0.1 0.8 0.9 0.0 0.1 0.0 172.8 0.0 0.1 0.0 0.3 2.9 1.3 0.0 0.0 0.7 4.1 0.1 39.8 19.7 14.4 5.4 0.0 0.1 0.1 0.0 112.3 20.5 0.7 0.0 0.2 25.6 0.4 0.0 0.0 14.6 0.0 0.3 0.0 0.1 1.6 0.0 7.9 0.9 3.6 0.4 0.0 0.0 0.2 47.6 8.6 0.0 0.1 0.0 0.0 1.3 0.0 2.2 0.0 0.1 0.1 0.1 0.0 5.7 0.9 0.2 0.1 0.0 0.0 1.1 0.7 0.2 4.1 0.1 0.1 0.0 0.0 4.6 0.1 4.2 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.2 0.8 0.8 0.6 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 0.2 0.0 114.2 0.0 0.0 0.0 25.0 0.0 0.0 1.8 0.0 0.0 1.0 1.5 0.1 0.7 0.0 0.0 0.5 0.2 0.0 1.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 0.4 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.1 NAA30 "C14orf35, FLJ35355, MAK3, Mak3p, NAT12" ENSG00000139977 "N-alpha-acetyltransferase 30, NatC catalytic subunit" Q147X3 14 57390544-57415906 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 107.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057824 Uncertain Supported Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA057824: AB_2683539" "unprognostic (5.13e-2)" "unprognostic (7.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (6.31e-2)" "unprognostic (1.84e-2)" "unprognostic (5.44e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.25e-8)" "unprognostic (1.77e-1)" "unprognostic (1.67e-1)" "unprognostic (5.75e-3)" "unprognostic (1.63e-1)" 9.6 7.7 9.7 7.2 11.3 15.0 9.6 10.6 11.8 7.8 6.5 8.4 9.9 9.1 7.1 11.3 7.4 7.1 14.2 11.6 11.6 12.4 16.7 6.4 9.0 8.6 9.3 14.9 9.0 12.5 5.7 13.4 9.2 10.1 7.9 12.0 8.0 10.1 31.8 8.3 8.7 10.1 9.3 8.3 7.0 18.5 12.4 9.0 10.6 27.3 9.1 8.2 6.0 9.4 19.4 18.2 10.2 16.7 16.8 21.9 17.1 22.1 21.3 16.5 15.0 16.5 13.9 14.1 19.0 18.4 12.5 20.1 18.5 14.3 27.4 24.7 9.4 11.4 10.1 14.5 17.5 23.1 12.8 15.0 20.7 15.0 24.9 18.4 25.8 17.3 11.3 13.6 22.1 22.1 19.5 13.4 11.0 17.8 20.0 15.3 29.4 11.0 16.9 17.4 21.8 11.5 18.7 18.3 23.0 18.2 23.6 11.9 22.7 25.7 27.0 14.2 14.3 10.1 13.2 16.9 17.1 11.5 18.7 0.8 0.4 0.2 1.2 0.9 1.2 1.0 1.1 1.8 0.3 1.1 1.2 1.2 0.2 2.4 2.8 0.6 1.7 0.4 9.7 11.3 10.6 11.8 11.6 11.6 8.6 9.3 9.2 9.3 12.4 9.4 11.8 9.6 6.3 10.1 16.7 41.0 11.8 8.6 25.0 13.5 16.5 10.9 34.9 17.2 8.0 3.7 18.8 18.3 20.1 11.6 9.8 12.5 107.1 9.0 13.1 17.0 21.0 9.0 20.3 11.6 15.6 13.1 12.8 10.8 7.0 14.9 11.0 25.5 9.9 10.1 20.3 13.7 6.1 13.2 12.1 37.6 13.7 8.2 23.2 10.3 9.9 13.3 8.2 16.6 18.9 14.5 13.8 13.5 18.1 18.9 13.6 17.9 9.5 15.3 19.7 13.3 15.4 69.2 20.5 25.5 41.2 22.2 17.0 13.3 12.6 16.7 NAV3 "KIAA0938, POMFIL1" ENSG00000067798 "Neuron navigator 3" Q8IVL0 12 77324641-78213010 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3;ovary: 18.3" "Group enriched" "Detected in many" 6 "Astrocytes: 882.1;Excitatory neurons: 1473.6;Inhibitory neurons: 753.8;Microglial cells: 534.0;Oligodendrocyte precursor cells: 786.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 9.7;basal ganglia: 15.0;cerebral cortex: 17.3;hippocampal formation: 13.6;white matter: 10.3" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.0;THP-1: 41.8;U-138 MG: 30.8;WM-115: 38.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032111, HPA061392" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane" Cytosol "HPA032111: AB_10603881, HPA061392: " "unprognostic (3.51e-1)" "unprognostic (6.72e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (2.14e-1)" "unprognostic (2.78e-1)" "unprognostic (3.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.06e-2)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (5.68e-7)" "unprognostic (6.86e-3)" "unprognostic (1.23e-1)" "unprognostic (1.58e-2)" "unprognostic (2.29e-3)" 3.8 4.8 9.7 1.0 15.0 0.5 4.0 0.9 17.3 1.2 0.0 1.7 0.3 2.0 2.9 1.9 2.2 5.1 1.9 13.6 0.0 0.4 1.0 3.3 0.6 0.7 0.4 18.3 0.5 0.4 3.1 2.2 0.0 2.1 0.8 5.2 0.9 2.5 1.3 2.6 0.6 2.5 1.4 8.0 0.8 2.8 1.6 1.9 1.2 3.4 0.4 3.3 1.7 10.3 3.5 8.7 0.6 0.2 8.5 18.1 0.3 26.5 20.9 10.7 5.3 1.7 0.6 0.2 1.9 22.0 7.2 2.5 7.8 4.0 19.3 0.1 0.2 0.2 3.9 0.2 6.7 0.1 0.2 6.2 0.2 47.0 11.1 9.3 16.4 0.1 0.0 0.1 26.2 0.5 0.2 12.0 2.7 0.3 2.1 1.0 2.1 0.0 1.7 0.1 0.6 0.0 1.6 0.3 3.5 0.8 0.1 41.8 14.1 30.8 8.1 12.0 18.2 1.2 0.0 0.7 8.8 0.5 38.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 9.7 15.0 0.9 17.3 13.6 0.0 0.7 0.4 0.0 1.4 1.6 10.3 11.1 19.2 10.0 882.1 0.0 3.6 8.4 0.2 0.0 5.0 3.8 3.8 3.4 0.0 7.5 0.0 0.0 0.1 0.0 0.2 0.0 4.2 10.4 4.2 8.2 5.6 16.4 0.0 1473.6 1.6 0.1 18.7 0.5 10.3 11.4 0.8 3.9 0.0 7.3 50.5 753.8 0.0 0.0 0.0 3.7 4.7 23.9 1.4 12.4 534.0 0.1 18.3 0.0 786.1 144.1 19.2 0.0 7.5 1.2 18.0 0.0 0.3 8.7 2.0 0.0 28.8 5.3 0.3 0.8 0.2 1.4 0.3 1.3 73.7 0.0 2.9 NBPF3 AE2 ENSG00000142794 "NBPF member 3" Q9H094 1 21440128-21485005 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 9.8" "Cell type enhanced" "Detected in many" "Early spermatids: 33.8;Excitatory neurons: 17.6;Inhibitory neurons: 18.4;Oligodendrocyte precursor cells: 29.1;Oligodendrocytes: 17.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 12.0;HHSteC: 12.0" "HPA042595, HPA043692, HPA044023, HPA046971, HPA058050" Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA042595: , HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (5.49e-2)" "unprognostic (1.19e-2)" "unprognostic (5.09e-3)" "unprognostic (2.57e-2)" "unprognostic (3.11e-1)" "unprognostic (2.01e-1)" "unprognostic (2.82e-2)" "unprognostic (2.10e-1)" "unprognostic (2.22e-3)" "unprognostic (1.09e-1)" "unprognostic (3.11e-3)" "unprognostic (1.63e-1)" "unprognostic (5.31e-5)" "unprognostic (8.35e-2)" "unprognostic (1.23e-2)" "unprognostic (2.69e-2)" "unprognostic (1.66e-2)" 1.4 2.0 1.4 0.7 1.4 0.7 1.7 1.4 2.1 1.8 1.3 1.9 0.1 0.9 1.3 1.2 1.3 0.1 1.1 1.3 1.3 2.1 1.6 0.8 0.9 1.5 1.3 1.5 1.4 1.4 2.2 1.6 1.3 1.5 0.9 1.5 1.5 0.9 0.7 1.7 1.6 1.0 1.3 1.5 2.0 9.8 1.4 1.1 1.7 0.0 1.4 1.5 1.1 1.3 1.6 1.6 0.0 4.3 2.9 1.1 4.9 3.7 12.0 3.3 2.9 2.9 4.3 3.0 1.2 6.9 0.8 0.2 2.2 2.6 0.3 1.7 3.0 2.3 0.2 0.9 12.0 1.1 1.3 0.8 0.8 3.1 0.1 1.2 0.4 0.0 0.2 0.6 0.4 5.3 0.0 2.6 0.7 2.1 3.3 0.0 0.0 2.4 0.3 1.5 3.4 3.7 5.2 1.0 3.5 1.0 1.3 1.7 3.5 1.1 2.2 4.6 1.1 0.0 1.8 4.7 0.3 2.2 1.4 0.0 0.2 1.0 1.7 0.3 2.4 0.4 0.7 1.4 0.1 0.2 1.2 1.6 0.1 0.7 0.0 0.0 0.8 0.9 1.4 1.4 1.4 2.1 1.3 1.3 1.5 1.3 1.3 1.3 1.4 1.3 1.6 0.0 3.7 14.0 1.9 1.3 2.8 1.2 2.8 1.8 3.8 2.8 2.9 1.5 1.3 1.8 6.2 3.7 2.7 0.8 0.0 1.2 33.8 1.9 1.5 2.3 0.0 2.1 17.6 2.5 1.1 3.4 4.1 3.2 2.5 1.8 3.6 1.1 0.9 0.0 18.4 2.8 4.1 1.6 6.7 4.3 2.8 3.0 0.0 6.5 1.9 1.0 0.0 29.1 17.2 2.4 0.2 1.9 0.9 1.6 1.4 2.2 5.9 2.0 0.0 2.8 2.3 15.7 8.0 2.2 3.0 2.5 3.4 4.0 1.1 2.2 NDEL1 "MITAP1, NDE1L1, NDE2, NUDEL" ENSG00000166579 "NudE neurodevelopment protein 1 like 1" Q9GZM8 17 8413131-8490411 "Predicted intracellular proteins" "Differentiation, Neurogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 134.5;Suprabasal keratinocytes: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 175.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017916 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "HPA017916: AB_1854337" "unprognostic (6.34e-2)" "unprognostic (4.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.35e-3)" "unprognostic (6.98e-3)" "unprognostic (1.70e-2)" "unprognostic (3.10e-1)" "unprognostic (7.77e-3)" "unprognostic (1.18e-1)" "unprognostic (1.66e-1)" "unprognostic (2.95e-3)" "unprognostic (4.66e-2)" "unprognostic (5.89e-2)" "unprognostic (6.73e-3)" "unprognostic (8.82e-2)" "unprognostic (1.01e-1)" "unprognostic (7.63e-3)" 42.8 60.3 18.2 37.0 23.1 109.8 33.2 19.4 26.2 36.6 17.6 30.9 18.4 29.2 20.3 54.7 32.1 40.7 30.0 23.8 20.9 19.8 43.9 44.4 23.2 18.0 19.2 46.6 27.8 18.0 35.0 39.9 20.9 25.5 23.1 25.3 32.5 22.3 43.6 91.3 24.8 26.7 15.3 29.0 25.8 26.4 20.6 24.4 23.2 31.1 26.8 37.8 39.8 23.5 41.9 36.6 34.2 29.4 50.9 61.9 28.1 87.2 72.6 61.4 64.0 32.0 22.2 24.0 28.9 97.1 34.8 47.7 30.9 34.6 62.9 40.1 50.1 48.0 59.8 38.7 54.5 18.4 98.4 41.2 66.7 52.8 60.0 44.7 49.8 37.0 29.0 27.6 54.1 17.9 27.2 15.7 14.9 26.2 20.4 28.2 26.9 19.8 27.7 23.6 16.2 17.8 52.9 25.4 29.4 36.0 17.3 12.6 65.6 48.7 18.4 45.4 48.4 19.3 42.5 19.3 61.0 27.4 50.3 85.5 28.3 98.2 35.1 27.6 37.0 25.5 31.3 34.8 23.9 26.1 30.4 27.9 175.0 32.8 24.7 20.6 36.5 36.3 18.2 23.1 19.4 26.2 23.8 20.9 18.0 19.2 20.9 15.3 20.6 23.5 48.4 12.8 20.9 12.1 33.8 79.0 55.3 18.3 27.3 13.9 24.1 20.4 17.5 12.8 18.1 12.9 20.9 18.9 39.7 36.8 9.8 13.6 86.8 34.8 21.5 26.4 4.2 37.5 27.0 12.2 37.1 26.4 47.9 63.5 80.5 13.3 18.5 12.8 14.1 8.4 22.0 37.1 20.3 13.2 74.0 134.5 12.8 40.8 32.0 18.7 13.2 8.8 19.6 14.6 19.6 24.0 42.6 14.7 38.2 36.0 21.8 5.8 11.3 14.1 6.6 24.7 40.1 8.3 10.0 25.0 136.7 57.3 40.1 11.8 17.6 73.4 NECTIN3 "CD113, CDw113, DKFZP566B0846, nectin-3, PPR3, PVRL3, PVRR3" ENSG00000177707 "Nectin cell adhesion molecule 3" Q9NQS3 3 111070071-111275563 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 54.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Syncytiotrophoblasts: 117.3;Theca cells: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 117.4;TIME: 170.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009869, HPA011038" Approved Approved "Cell Junctions,Cytosol" NA NA 41000000 "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "Cell Junctions" "CAB009869: AB_2284699, HPA011038: AB_1079719" "unprognostic (3.76e-2)" "unprognostic (3.81e-3)" "unprognostic (1.74e-1)" "unprognostic (1.97e-2)" "unprognostic (1.02e-1)" "unprognostic (9.77e-2)" "unprognostic (3.26e-3)" "unprognostic (3.77e-1)" "unprognostic (7.58e-2)" "unprognostic (3.94e-2)" "unprognostic (5.33e-2)" "unprognostic (7.04e-2)" "prognostic favorable (9.82e-7)" "unprognostic (2.01e-1)" "unprognostic (1.97e-1)" "unprognostic (2.67e-1)" "unprognostic (1.05e-1)" 8.9 4.8 3.9 4.7 6.0 0.2 4.3 6.2 7.5 7.3 0.0 23.0 32.9 7.6 1.5 4.6 9.7 8.2 5.3 6.6 5.0 12.0 29.4 10.4 3.0 10.8 5.6 16.1 7.1 4.6 1.1 22.7 6.7 11.7 23.1 7.3 5.6 8.4 1.7 1.4 21.2 13.6 7.3 3.9 24.6 54.7 12.4 1.5 42.5 7.1 3.1 6.0 3.0 8.8 0.2 36.2 117.4 7.7 45.7 85.3 7.2 78.6 82.7 47.8 39.7 33.4 16.7 0.0 25.4 112.4 26.6 0.6 33.2 11.4 87.4 0.9 8.8 0.1 12.1 2.4 77.2 5.9 1.1 43.6 4.6 31.7 30.3 42.5 40.8 1.5 0.0 30.2 104.2 0.2 7.8 0.0 33.0 11.0 12.9 0.0 58.2 0.2 26.9 19.2 2.9 20.8 1.6 0.0 15.7 38.9 1.3 0.5 170.4 58.8 24.9 11.1 47.2 17.2 0.0 0.2 37.9 0.1 56.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 6.0 6.2 7.5 6.6 5.0 10.8 5.6 6.7 7.3 12.4 8.8 8.3 25.6 11.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.6 3.0 0.0 0.0 3.1 12.9 0.0 3.9 4.5 0.0 0.0 6.5 0.0 9.0 11.4 4.4 0.0 0.0 0.0 18.9 9.4 9.5 0.0 13.7 1.3 6.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 2.8 0.0 0.0 7.1 0.7 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 117.3 5.3 31.5 0.0 0.0 NEDD1 "GCP-WD, TUBGCP7" ENSG00000139350 "NEDD1 gamma-tubulin ring complex targeting factor" Q8NHV4 12 96907224-96953780 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 255.8;Late spermatids: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 133.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038591 Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Centrosome" "HPA038591: AB_10674688" "unprognostic (7.93e-2)" "unprognostic (3.18e-1)" "unprognostic (7.00e-2)" "unprognostic (1.19e-2)" "unprognostic (2.21e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (1.94e-4)" "prognostic unfavorable (3.70e-4)" "unprognostic (1.81e-2)" "unprognostic (9.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.56e-1)" "unprognostic (2.46e-3)" "unprognostic (7.29e-2)" "unprognostic (2.28e-1)" "unprognostic (1.34e-1)" "unprognostic (5.59e-2)" 9.1 5.8 3.4 9.7 4.3 15.2 12.8 4.0 3.9 9.9 7.7 8.3 7.1 12.7 6.4 10.0 9.1 7.5 9.2 3.1 4.7 8.9 6.3 8.8 15.4 5.0 4.5 9.8 7.1 14.9 3.8 11.0 4.7 10.6 9.7 7.2 6.8 8.2 38.0 8.2 6.9 13.1 4.8 13.4 7.2 23.6 3.7 22.5 10.5 25.6 15.2 9.6 6.1 6.3 39.4 25.8 43.3 26.8 21.1 19.0 30.7 133.1 47.0 60.5 51.7 17.0 14.2 24.1 12.6 107.7 28.8 34.5 29.5 31.0 80.7 46.7 26.2 30.2 16.1 15.1 17.5 41.8 26.2 14.1 24.9 37.2 28.3 39.8 30.0 41.0 17.8 17.3 43.9 16.3 76.1 19.0 23.8 20.6 80.8 40.0 43.7 24.0 25.0 25.7 13.4 23.6 37.4 20.9 23.7 33.5 28.2 14.6 21.5 38.0 28.8 27.2 31.9 17.0 22.0 32.3 11.7 20.9 46.7 14.1 8.5 25.6 13.8 13.8 15.8 11.1 15.4 15.0 7.4 10.4 15.7 12.5 6.3 19.9 10.2 5.7 17.8 9.4 3.4 4.3 4.0 3.9 3.1 4.7 5.0 4.5 4.7 4.8 3.7 6.3 18.8 9.6 11.5 11.4 19.1 19.4 28.1 7.3 13.1 8.0 10.4 6.9 10.5 21.5 11.9 16.5 0.0 8.2 20.5 6.3 9.8 9.8 255.8 15.3 10.0 14.6 6.1 34.1 3.7 8.2 13.9 13.3 8.6 9.7 16.5 9.3 15.0 4.8 8.6 18.5 3.0 7.5 4.1 8.1 9.2 92.0 12.5 9.4 7.2 15.9 7.5 11.5 17.5 9.0 15.1 8.3 8.3 10.1 13.3 49.6 4.7 11.2 21.8 8.4 19.7 13.9 13.6 34.3 26.0 12.0 14.1 4.0 24.6 9.8 8.0 18.3 NEK10 FLJ32685 ENSG00000163491 "NIMA related kinase 10" Q6ZWH5 3 27110085-27369460 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 36.6;tongue: 20.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 123.5;Endometrial ciliated cells: 59.3;Excitatory neurons: 131.4;Inhibitory neurons: 130.2;Late spermatids: 61.7;Respiratory ciliated cells: 104.2" "Cancer enriched" "Detected in single" 5 "breast cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 6.0;LHCN-M2: 8.2;U-2 OS: 6.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038941 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Vesicles Nucleoplasm "HPA038941: AB_10673600" "prognostic favorable (4.20e-4)" "unprognostic (2.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.15e-2)" "unprognostic (3.37e-2)" "unprognostic (3.02e-1)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-1)" "unprognostic (1.93e-2)" "unprognostic (2.20e-3)" "unprognostic (1.37e-1)" "unprognostic (7.67e-2)" "unprognostic (1.33e-2)" "unprognostic (1.38e-2)" "unprognostic (1.57e-3)" "unprognostic (2.14e-1)" 0.2 0.3 3.0 0.3 5.3 0.3 14.0 0.0 9.4 1.4 3.3 2.0 2.5 0.8 8.3 1.8 11.0 1.4 3.3 9.6 5.0 1.7 2.5 2.4 0.5 3.3 5.7 0.7 0.7 0.4 3.4 0.1 2.7 1.7 0.5 6.2 0.3 1.2 12.4 0.3 0.8 0.3 2.3 0.4 1.0 36.6 6.1 0.5 0.7 20.0 0.6 1.2 0.2 0.9 0.8 1.6 0.8 0.9 0.6 1.5 0.3 6.0 0.9 1.6 1.4 0.0 0.4 0.5 1.4 2.5 1.1 0.1 0.4 0.4 1.7 1.1 0.6 0.1 3.4 2.9 0.1 0.3 0.8 1.8 0.4 2.5 0.1 2.0 1.1 3.4 0.1 0.6 8.2 0.1 0.6 0.4 0.5 0.2 0.2 0.8 0.3 0.2 3.0 0.5 0.1 0.2 0.9 0.3 0.4 0.5 4.8 0.3 0.7 4.3 6.8 0.2 0.6 0.2 0.2 0.4 3.6 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 5.3 0.0 9.4 9.6 5.0 3.3 5.7 2.7 2.3 6.1 0.9 1.5 6.4 0.0 11.4 0.3 0.3 0.3 3.2 0.0 14.5 25.8 7.4 12.9 4.3 9.3 1.8 87.6 0.0 0.8 0.2 0.0 0.4 123.5 59.3 1.3 2.4 0.0 0.0 131.4 0.0 0.3 3.1 0.0 7.7 0.0 1.1 0.7 1.3 0.2 0.0 130.2 0.4 12.2 1.0 0.8 61.7 1.8 1.1 0.0 32.8 0.1 1.0 1.0 20.6 12.9 0.2 2.7 1.2 0.1 1.9 2.1 0.3 104.2 19.1 0.0 14.9 2.4 32.2 2.2 0.1 0.4 0.0 1.1 3.7 0.6 0.4 NEK7 ENSG00000151414 "NIMA related kinase 7" Q8TDX7 1 198156994-198322420 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 140.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 172.6;Oligodendrocyte precursor cells: 131.2;Oligodendrocytes: 153.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 554.5;fHDF/TERT166: 753.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015520, HPA018193" Approved Supported Nucleoplasm Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA015520: AB_1854371, HPA018193: AB_1854372" "unprognostic (2.08e-1)" "unprognostic (2.98e-2)" "unprognostic (1.65e-1)" "unprognostic (5.38e-2)" "unprognostic (4.26e-2)" "unprognostic (3.00e-2)" "unprognostic (2.14e-2)" "unprognostic (5.47e-2)" "unprognostic (4.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.46e-3)" "unprognostic (2.82e-1)" "unprognostic (1.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.74e-1)" "unprognostic (2.05e-2)" "unprognostic (1.56e-1)" 63.8 49.9 48.3 29.3 58.7 11.1 27.7 45.9 53.3 26.1 35.7 30.0 21.1 26.6 19.7 31.2 22.3 27.2 140.4 39.5 56.1 29.3 30.0 41.6 30.8 61.1 51.3 29.6 20.3 25.1 12.3 42.1 60.0 27.1 23.3 19.6 22.3 36.5 56.6 14.9 25.3 32.2 59.7 32.1 20.1 13.7 49.1 27.7 26.8 63.7 23.6 30.9 20.1 64.2 47.8 12.3 14.8 6.0 37.5 42.6 17.4 554.5 227.6 218.7 102.9 23.0 46.2 17.1 39.4 753.3 12.6 29.0 22.7 30.3 220.8 56.0 32.7 23.6 48.7 9.6 45.3 40.2 46.3 26.7 25.3 144.8 43.5 82.2 42.4 140.0 18.8 41.2 102.3 15.1 34.7 23.4 8.4 37.5 9.9 18.5 36.5 30.7 37.3 24.5 9.5 17.0 92.1 53.0 63.5 20.6 38.8 36.0 95.7 61.8 52.0 178.6 58.9 29.3 28.5 11.8 26.9 36.3 48.7 1.8 2.2 3.3 2.9 1.8 12.8 1.4 3.2 4.1 2.0 1.9 2.7 3.1 6.0 3.6 1.6 1.3 6.0 1.4 48.3 58.7 45.9 53.3 39.5 56.1 61.1 51.3 60.0 59.7 49.1 64.2 34.3 28.9 30.7 78.0 32.4 51.4 15.0 10.2 33.6 8.2 22.8 18.2 172.6 10.0 18.7 18.4 14.6 15.0 32.9 25.8 11.7 10.6 2.8 21.6 20.9 29.3 19.8 32.6 17.0 19.6 15.9 30.0 18.8 19.6 8.8 11.8 40.4 23.5 17.5 3.3 34.6 19.5 8.2 49.5 51.6 3.3 29.2 35.5 30.2 124.6 29.0 11.4 15.5 131.2 153.5 50.1 19.3 38.4 28.5 30.6 25.1 16.6 27.9 24.2 19.7 28.1 35.9 7.7 6.0 29.2 49.2 64.3 41.6 28.7 15.6 33.1 NF2 "ACN, BANF, merlin, SCH" ENSG00000186575 "Neurofibromin 2" P35240 22 29603556-29698598 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 77.1;Late spermatids: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003097, CAB005385" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB005385: AB_2298548, HPA003097: AB_1079473" "unprognostic (3.27e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.14e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.61e-1)" "unprognostic (3.67e-2)" "unprognostic (2.16e-2)" "unprognostic (2.01e-3)" "unprognostic (4.66e-1)" "prognostic favorable (2.89e-5)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (9.62e-2)" 8.8 13.6 19.7 8.4 17.2 8.0 7.6 13.6 28.7 8.9 10.7 10.8 6.2 11.1 6.2 13.4 8.6 5.3 21.4 27.3 13.9 17.2 10.5 9.3 6.4 14.4 18.1 8.5 12.7 27.4 9.5 4.6 14.3 9.9 5.4 7.3 8.5 6.7 22.8 10.2 8.8 8.0 14.3 9.9 10.0 20.9 17.6 9.3 11.1 19.1 7.1 9.3 7.7 16.6 75.8 36.7 12.2 74.3 21.5 22.0 7.7 57.3 37.9 74.1 53.7 32.7 18.4 21.1 50.4 69.9 48.9 27.1 25.1 37.8 52.0 31.9 12.5 26.8 24.4 26.4 22.4 35.1 28.6 20.1 16.4 53.3 51.0 21.8 47.7 13.7 12.0 18.7 64.5 35.1 21.4 16.6 8.3 16.9 20.4 24.2 56.8 18.8 68.5 37.3 17.0 11.6 36.0 24.5 14.0 9.4 14.9 15.4 92.7 101.1 109.6 44.8 112.5 30.0 26.7 25.5 27.0 14.5 68.5 10.0 10.0 4.2 15.5 14.7 13.1 8.3 11.5 10.4 15.1 8.6 9.7 9.2 2.3 13.2 21.0 10.2 10.7 12.2 19.7 17.2 13.6 28.7 27.3 13.9 14.4 18.1 14.3 14.3 17.6 16.6 8.1 6.4 20.1 14.7 9.4 14.1 11.6 9.8 8.6 16.3 14.5 9.0 23.1 18.6 10.0 14.7 10.4 11.7 12.7 9.0 21.5 40.0 77.1 14.5 17.7 13.2 13.1 13.9 27.5 24.9 6.7 12.5 7.7 15.2 22.9 12.2 11.7 14.4 13.5 30.3 27.1 7.9 6.1 14.7 7.5 121.4 7.2 10.2 8.8 18.7 8.6 19.1 14.4 17.6 16.7 40.1 14.5 12.4 14.7 13.6 10.5 30.1 8.6 9.6 6.6 13.7 15.6 29.5 8.1 15.5 14.3 3.8 12.9 17.4 11.2 9.5 NFASC "FLJ46866, KIAA0756, NF, NRCAML" ENSG00000163531 Neurofascin O94856 1 204828651-205022822 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 151.0;Excitatory neurons: 148.4;Horizontal cells: 220.4;Inhibitory neurons: 139.0;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 226.6;Rod photoreceptor cells: 195.5" "Cancer enriched" "Detected in many" 5 "glioma: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 27.6;fHDF/TERT166: 50.3;hTERT-RPE1: 24.0;SCLC-21H: 22.8;U-138 MG: 62.7;U-87 MG: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008832 Enhanced NA NA 2200000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "HPA008832: AB_1854411" "unprognostic (1.71e-1)" "unprognostic (1.07e-1)" "unprognostic (2.62e-1)" "unprognostic (3.39e-2)" "unprognostic (6.65e-2)" "unprognostic (1.18e-2)" "unprognostic (3.71e-3)" "unprognostic (3.37e-1)" "unprognostic (6.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.21e-5)" "unprognostic (3.76e-1)" "prognostic unfavorable (2.93e-5)" "unprognostic (1.56e-3)" "unprognostic (1.91e-1)" "unprognostic (6.90e-2)" "unprognostic (5.26e-3)" 5.2 7.5 7.8 3.7 31.5 0.1 3.2 8.4 15.2 5.0 0.0 8.6 4.5 8.3 9.0 10.0 12.1 5.9 15.3 10.7 5.6 9.8 1.9 5.0 2.3 13.1 14.1 10.1 5.9 1.0 5.6 10.6 7.8 7.5 5.9 22.6 2.1 16.3 3.0 4.3 5.0 14.2 3.9 6.5 4.4 1.5 35.6 0.6 2.9 3.8 2.9 9.4 7.7 50.1 0.0 0.1 3.1 0.1 0.4 1.0 0.1 27.6 0.0 19.9 5.9 0.2 0.1 0.0 0.1 50.3 18.5 13.4 0.6 0.8 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 12.7 0.7 24.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 7.0 0.9 0.3 0.0 2.3 0.0 0.0 0.0 22.8 1.3 0.0 1.5 0.0 2.0 0.3 0.0 0.0 62.7 13.5 0.1 0.0 0.0 0.0 0.0 31.3 0.0 16.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 31.5 8.4 15.2 10.7 5.6 13.1 14.1 7.8 3.9 35.6 50.1 2.5 0.0 0.6 64.3 0.0 2.2 1.5 1.9 0.6 151.0 1.7 10.5 23.9 1.5 1.5 0.0 12.5 0.5 0.0 0.3 0.0 0.2 7.3 0.5 0.4 7.6 37.8 0.0 148.4 0.0 0.5 14.2 1.1 0.1 0.0 0.1 3.3 1.7 0.4 220.4 139.0 6.0 0.0 0.6 1.9 17.9 6.5 0.4 1.8 15.0 0.0 14.2 0.0 87.9 226.6 0.5 0.5 5.7 0.0 1.1 0.0 1.5 5.9 195.5 52.6 2.3 49.9 1.7 3.9 5.5 4.7 0.7 0.3 0.7 1.0 0.8 NFAT5 "KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP" ENSG00000102908 "Nuclear factor of activated T cells 5" O94916 16 69565094-69704666 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 281.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SiHa: 22.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057304, HPA069711" Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 10: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA057304: AB_2683407, HPA069711: AB_2686180" "unprognostic (2.71e-1)" "unprognostic (1.50e-2)" "unprognostic (1.77e-1)" "unprognostic (3.57e-2)" "unprognostic (5.65e-3)" "unprognostic (2.08e-1)" "unprognostic (2.97e-2)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (3.56e-2)" "unprognostic (4.05e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.08e-4)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (6.32e-2)" "unprognostic (9.42e-2)" 2.3 3.1 0.6 2.8 1.2 5.6 2.1 0.5 3.7 3.7 0.0 2.0 0.7 3.3 0.7 2.9 1.9 1.5 2.0 1.4 2.2 2.6 2.3 3.1 1.1 0.0 0.6 2.5 1.6 4.0 2.0 4.2 0.0 2.3 1.5 4.2 3.7 2.4 2.7 3.5 1.9 1.8 0.0 2.5 2.3 1.4 3.0 2.2 3.6 4.8 1.4 2.7 3.1 0.0 8.4 10.1 4.8 5.0 5.8 6.0 6.4 7.2 8.6 6.6 4.2 4.5 4.2 4.5 5.8 5.8 3.4 7.3 3.9 3.1 4.2 2.9 3.2 2.6 2.8 6.2 3.4 3.5 5.5 3.5 1.1 6.4 5.9 5.4 5.5 2.3 7.2 1.1 3.3 3.2 2.8 1.7 2.5 1.1 2.5 4.5 2.2 1.7 2.5 8.0 3.1 0.9 22.2 1.3 2.6 4.1 3.3 1.3 13.1 5.7 5.6 4.8 2.2 4.6 4.9 7.3 5.1 3.4 3.6 0.4 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.3 0.1 0.2 0.1 0.0 0.9 0.0 0.2 0.5 0.1 0.0 0.6 1.2 0.5 3.7 1.4 2.2 0.0 0.6 0.0 0.0 3.0 0.0 65.0 48.1 49.7 236.7 55.7 148.1 94.8 42.5 155.4 51.8 61.6 42.9 9.2 30.0 43.3 145.3 85.5 60.6 69.4 27.8 5.9 17.8 7.2 93.7 87.8 93.6 24.5 27.3 281.8 12.7 15.9 60.9 38.2 158.3 19.7 31.0 52.8 28.3 17.6 60.6 189.3 29.1 28.5 21.7 169.5 6.9 59.4 58.2 58.7 172.4 37.4 45.7 36.0 177.4 167.2 23.7 29.3 54.9 50.2 83.1 24.7 14.6 31.8 62.4 26.3 72.0 51.4 84.5 48.8 77.9 140.1 50.9 57.4 43.1 20.8 105.7 NFATC4 NFAT3 ENSG00000100968 "Nuclear factor of activated T cells 4" Q14934 14 24365673-24379604 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 58.8;Endometrial stromal cells: 28.3;Fibroblasts: 22.8;Sertoli cells: 26.3;Smooth muscle cells: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 36.8;BJ hTERT+: 49.5;hTERT-RPE1: 42.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA031641, CAB032859, HPA076526" Uncertain Supported "Nuclear speckles,Cytosol" No No "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles, Cytosol" "CAB032859: AB_1128521, HPA031641: AB_10600826, HPA076526: AB_2686805" "unprognostic (3.51e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.84e-4)" "unprognostic (8.08e-2)" "unprognostic (1.67e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.39e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (1.81e-6)" "unprognostic (1.47e-2)" "unprognostic (1.07e-1)" "unprognostic (1.35e-1)" "unprognostic (4.19e-2)" 48.4 54.9 9.1 6.0 9.4 0.6 47.2 8.6 10.5 126.0 9.0 71.9 4.5 82.1 13.7 22.2 82.6 17.8 30.2 9.0 9.3 35.5 5.6 30.2 4.8 10.3 9.4 142.7 13.8 9.0 37.9 18.2 8.8 51.5 5.0 2.8 20.5 16.2 9.0 25.0 29.9 18.8 8.2 17.7 35.5 42.7 9.7 1.7 50.4 2.5 3.6 66.2 65.9 8.5 0.0 0.1 17.8 0.0 25.4 36.8 0.1 17.3 49.5 23.0 20.0 0.0 14.6 14.9 0.5 25.0 1.6 0.0 7.1 0.3 13.9 0.0 0.6 11.3 20.6 0.0 12.3 0.0 0.0 26.8 0.3 13.9 0.1 42.5 18.2 4.7 3.7 0.0 4.5 0.8 0.0 1.7 2.3 1.0 0.1 1.1 1.6 2.0 0.0 0.2 2.9 11.9 0.0 3.3 5.7 8.7 10.3 4.5 10.3 21.3 4.4 20.5 0.0 10.4 1.6 11.0 4.4 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 9.4 8.6 10.5 9.0 9.3 10.3 9.4 8.8 8.2 9.7 8.5 4.1 3.2 8.1 58.8 1.1 4.5 0.9 1.9 0.6 1.3 3.3 2.8 7.8 0.0 4.8 0.0 0.0 0.6 0.0 0.8 0.0 2.8 4.4 2.5 28.3 4.6 7.7 0.0 0.1 0.2 0.6 22.8 3.6 6.4 0.0 4.1 1.4 0.2 0.6 0.0 0.2 3.4 10.2 0.0 6.8 6.5 17.4 0.4 7.2 13.1 0.0 7.6 0.0 1.0 0.2 0.6 0.3 7.5 0.2 0.8 0.4 0.2 2.1 1.5 26.3 4.3 27.1 12.5 2.9 1.0 3.4 0.5 0.9 6.0 1.6 2.3 NIBAN2 "bA356B19.6, C9orf88, DKFZP434H0820, FAM129B, FLJ13518, FLJ22151, FLJ22298, MINERVA" ENSG00000136830 "Niban apoptosis regulator 2" Q96TA1 9 127505339-127578989 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 606.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 73.6;Extravillous trophoblasts: 40.5;Hofbauer cells: 23.0;Syncytiotrophoblasts: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021284, HPA021417, HPA023261, HPA024312" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA021284: AB_1848373, HPA021417: AB_1848374, HPA023261: AB_1848375, HPA024312: AB_1848376" "unprognostic (3.05e-3)" "unprognostic (9.47e-2)" "unprognostic (1.14e-3)" "unprognostic (4.07e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-1)" "unprognostic (3.14e-2)" "unprognostic (2.57e-3)" "unprognostic (1.40e-1)" "unprognostic (1.68e-2)" "unprognostic (1.17e-3)" "unprognostic (6.45e-2)" "unprognostic (3.75e-2)" "unprognostic (1.24e-2)" "unprognostic (1.31e-1)" "unprognostic (8.40e-2)" "unprognostic (8.20e-3)" 48.7 107.5 26.7 36.6 24.7 27.3 42.0 25.2 24.5 96.0 45.3 74.6 50.8 38.9 12.6 606.7 39.4 39.6 39.4 22.7 35.0 72.3 16.7 121.9 6.6 48.9 34.3 31.6 142.6 26.2 34.0 84.8 36.3 66.5 30.3 2.7 142.1 32.2 13.6 111.3 53.9 22.0 39.7 32.2 83.3 11.0 34.7 5.6 110.6 11.3 53.6 68.4 189.6 31.9 134.0 149.8 29.9 39.3 87.9 170.1 138.2 259.1 238.5 140.1 86.4 48.2 143.7 0.4 100.4 295.5 172.9 217.5 25.9 192.2 45.9 25.2 27.5 22.8 218.9 50.4 173.1 1.0 62.0 187.3 118.3 231.4 80.8 256.8 213.6 8.4 43.5 1.2 269.8 157.3 1.6 37.6 30.9 228.0 194.4 16.0 99.9 70.1 120.5 105.6 47.4 22.1 212.3 149.0 93.4 42.1 98.2 7.5 279.9 143.1 62.4 182.2 218.0 2.5 5.1 0.6 403.3 21.6 271.1 0.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 26.7 24.7 25.2 24.5 22.7 35.0 48.9 34.3 36.3 39.7 34.7 31.9 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 73.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 40.5 4.2 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 120.9 0.1 0.0 0.0 0.0 NIPAL3 "DJ462O23.2, NPAL3" ENSG00000001461 "NIPA like domain containing 3" Q6P499 1 24415802-24472976 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 88.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.5;Oligodendrocytes: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039978 Approved Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA039978: AB_10697712" "unprognostic (9.36e-2)" "unprognostic (7.63e-2)" "unprognostic (2.88e-2)" "unprognostic (1.19e-2)" "unprognostic (5.96e-2)" "unprognostic (5.38e-2)" "unprognostic (3.72e-3)" "unprognostic (3.60e-2)" "unprognostic (2.43e-1)" "unprognostic (6.66e-2)" "unprognostic (2.79e-1)" "unprognostic (3.14e-1)" "prognostic favorable (3.03e-7)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (3.95e-4)" "unprognostic (2.85e-1)" 8.4 7.4 49.6 8.4 67.3 8.4 12.9 67.7 58.5 9.6 25.8 13.8 11.3 6.2 11.7 15.9 14.6 8.9 12.8 43.6 58.1 13.8 3.5 13.9 11.6 61.8 58.6 7.2 17.1 21.9 7.3 3.5 65.0 55.9 14.4 27.7 15.2 7.6 5.9 14.0 12.7 12.3 56.1 7.8 14.8 4.9 65.0 13.2 29.2 11.9 13.1 8.0 10.4 88.5 32.4 12.1 1.1 4.2 18.9 20.7 4.5 101.8 71.7 35.0 26.2 4.5 36.4 15.4 30.2 55.2 7.3 31.5 12.5 37.1 37.3 29.5 38.1 16.0 18.5 5.4 17.7 14.2 14.4 20.7 36.1 22.3 75.7 34.8 12.2 27.5 9.5 9.7 22.4 7.2 11.5 6.6 8.3 15.4 34.0 5.5 0.1 17.1 41.6 10.1 44.6 4.3 13.1 19.5 26.9 8.6 26.0 10.6 17.9 31.5 6.7 10.9 22.9 29.4 24.1 5.4 21.4 26.8 28.8 16.9 5.8 7.9 16.7 5.7 16.9 22.1 28.8 22.5 11.2 20.1 38.9 24.8 2.5 15.6 4.2 14.6 31.8 16.0 49.6 67.3 67.7 58.5 43.6 58.1 61.8 58.6 65.0 56.1 65.0 88.5 17.1 48.1 27.5 8.8 15.4 9.2 13.5 25.7 14.8 50.3 15.9 12.2 25.9 15.7 24.7 40.5 110.5 3.8 32.1 25.0 3.9 13.1 3.6 11.0 3.5 10.2 18.7 26.1 29.3 15.5 4.7 7.4 16.8 18.3 13.3 10.5 9.3 3.8 4.5 13.5 32.2 16.7 16.2 7.0 7.8 8.0 4.1 5.5 14.2 10.3 8.6 18.7 23.7 24.6 91.8 22.6 22.6 5.3 16.0 34.5 33.2 4.5 16.5 53.6 0.0 4.4 5.9 2.6 6.0 20.0 16.3 4.2 25.3 8.2 17.2 20.9 NKX2-6 "CSX2, NKX4-2" ENSG00000180053 "NK2 homeobox 6" A6NCS4 8 23701740-23706756 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "salivary gland: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTEC/SVTERT24-B: 5.6;JURKAT: 2.1;LHCN-M2: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA025288 Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA025288: " "unprognostic (1.86e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 2.1 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NLRP10 "CLR11.1, NALP10, NOD8, PAN5, Pynod" ENSG00000182261 "NLR family pyrin domain containing 10" Q86W26 11 7957537-7965426 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skin 1: 6.3" "Cell type enriched" "Detected in single" 5 "Microglial cells: 1.0" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 22.3;BJ: 5.9;HBF TERT88: 7.7;LHCN-M2: 3.7" "Region enhanced" "Detected in some" "olfactory bulb: 2.1" "HPA039498, HPA040101" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" Nucleoplasm "Nuclear membrane" "HPA039498: AB_10795679, HPA040101: AB_10795519" "unprognostic (4.06e-1)" "unprognostic (4.34e-1)" "unprognostic (9.78e-3)" "unprognostic (2.87e-2)" 0.0 0.0 0.1 0.0 0.0 0.1 1.4 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.3 0.0 0.0 0.1 0.0 0.3 0.1 5.9 2.8 1.3 2.8 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 1.0 7.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.3 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.9 2.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 NPLOC4 "FLJ20657, KIAA1499, NPL4" ENSG00000182446 "NPL4 homolog, ubiquitin recognition factor" Q8TAT6 17 81556887-81648465 "Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 164.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 20.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021560, HPA023295" Enhanced Supported Nucleoplasm,Cytosol NA NA 30000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA021560: AB_1854586, HPA023295: AB_1854587" "unprognostic (3.17e-1)" "unprognostic (2.98e-1)" "unprognostic (1.78e-1)" "unprognostic (1.00e-3)" "unprognostic (8.72e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (1.16e-5)" "unprognostic (1.06e-2)" "unprognostic (4.42e-1)" "unprognostic (2.97e-1)" "unprognostic (4.15e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (6.95e-7)" "unprognostic (1.01e-1)" "unprognostic (6.98e-2)" "unprognostic (6.51e-2)" "unprognostic (1.72e-1)" 37.3 46.6 27.2 32.4 27.6 41.7 32.0 22.2 28.3 30.4 27.1 35.2 24.5 35.3 23.5 51.5 28.8 23.3 58.4 26.6 31.2 42.2 54.8 37.9 33.2 31.8 27.2 25.9 36.7 29.7 33.2 27.1 28.5 33.3 21.3 20.1 32.4 22.7 164.3 42.1 34.4 29.3 24.1 42.8 36.8 42.8 28.7 33.4 28.4 55.5 28.8 33.2 31.7 32.8 91.9 118.6 46.2 72.1 56.0 46.0 57.2 74.2 82.3 120.4 110.6 90.7 80.2 67.2 57.9 87.7 87.8 72.5 46.0 62.6 104.5 43.0 60.8 77.5 95.5 81.5 53.4 83.4 95.4 45.8 59.1 113.2 40.1 57.7 124.8 62.0 84.1 99.1 73.6 59.5 113.0 45.2 54.3 45.5 74.0 73.6 73.8 54.4 43.6 86.8 61.6 70.6 92.6 127.4 85.7 87.1 100.1 60.9 89.6 156.1 108.1 86.1 121.4 74.8 57.9 84.0 124.6 55.2 102.9 4.1 20.0 4.4 4.6 4.9 2.8 4.7 3.1 3.7 6.3 3.3 2.8 3.7 5.6 2.8 3.1 4.8 3.2 10.0 27.2 27.6 22.2 28.3 26.6 31.2 31.8 27.2 28.5 24.1 28.7 32.8 19.2 12.8 18.1 24.8 15.3 17.6 16.2 12.7 7.4 24.3 19.5 16.1 44.5 11.5 18.5 20.2 29.2 19.5 22.2 38.9 1.9 19.0 96.2 32.8 19.6 22.2 30.5 20.6 38.0 37.4 21.3 15.9 26.0 38.8 3.8 29.2 27.1 54.3 19.1 20.2 36.4 17.2 8.2 27.3 18.7 79.6 17.7 22.8 12.4 19.7 28.7 19.6 14.4 23.1 38.6 47.2 22.8 12.8 16.5 28.4 22.2 27.9 21.5 33.5 19.7 22.3 18.5 29.7 23.9 15.7 24.2 37.1 16.9 19.3 18.9 28.7 NR3C1 "GR, GRL" ENSG00000113580 "Nuclear receptor subfamily 3 group C member 1" P04150 5 143277931-143435512 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Receptor, RNA-binding" "Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 411.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004248, CAB010435" Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" Mitochondria "CAB010435: AB_2155784, HPA004248: AB_1078976" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.43e-2)" "unprognostic (2.74e-1)" "unprognostic (4.19e-1)" "unprognostic (1.39e-1)" "unprognostic (2.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.15e-1)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.72e-6)" "unprognostic (9.06e-3)" "unprognostic (1.02e-1)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" 35.3 11.8 15.2 22.6 18.1 49.4 25.5 34.0 24.7 19.7 18.2 13.7 19.2 18.8 13.6 25.7 18.8 21.1 24.2 14.9 25.0 19.2 39.8 31.9 25.6 18.1 14.9 21.1 14.7 33.8 16.2 46.9 16.1 19.7 14.5 9.5 16.1 20.0 45.0 20.4 18.0 23.8 15.0 24.5 16.0 11.1 21.6 40.0 25.6 40.1 27.3 18.2 16.0 28.5 30.4 60.6 4.4 0.1 38.2 42.3 5.2 46.5 55.3 39.3 45.1 4.5 39.7 26.8 20.8 68.6 46.0 28.1 0.3 36.6 48.3 15.2 21.0 6.9 77.0 13.5 35.7 28.1 20.6 30.8 46.3 64.7 62.5 49.0 15.0 12.1 10.3 98.8 35.1 10.9 16.7 20.0 11.9 5.1 13.0 6.0 41.4 58.0 11.5 2.1 8.0 6.1 81.3 11.7 19.4 4.9 5.3 39.8 35.8 94.7 18.7 45.7 35.9 20.1 19.7 41.5 49.7 28.5 33.6 67.4 21.3 38.9 18.3 24.2 15.1 15.9 18.6 17.9 28.5 22.3 17.8 17.2 68.4 23.1 23.6 25.9 12.8 17.3 15.2 18.1 34.0 24.7 14.9 25.0 18.1 14.9 16.1 15.0 21.6 28.5 152.3 67.3 69.1 71.2 134.1 58.8 35.9 37.9 79.6 13.1 39.0 55.8 43.4 57.2 41.2 25.8 16.7 48.9 158.3 22.9 17.6 30.8 165.6 8.1 30.1 82.3 28.1 55.9 411.4 33.3 39.5 112.2 23.9 10.4 89.3 7.5 63.5 193.9 53.2 37.0 169.5 4.1 10.2 66.3 99.2 144.1 63.0 97.4 53.4 241.7 87.6 34.6 83.4 240.3 237.5 35.9 17.9 71.5 115.1 46.2 25.3 67.9 37.9 65.0 151.2 181.9 105.0 24.5 40.1 57.4 56.3 36.5 204.5 12.6 12.9 14.3 NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Group enriched" "Detected in many" 17 "Excitatory neurons: 1466.4;Inhibitory neurons: 411.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 55.3" "Lineage enriched" "Detected in many" 5 "monocytes: 55.3" "Cell line enhanced" "Detected in many" "A549: 132.5;BJ: 91.3;fHDF/TERT166: 98.1;GAMG: 95.4;U-2197: 84.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA010964: AB_1854641" "unprognostic (5.76e-3)" "unprognostic (8.60e-2)" "unprognostic (1.96e-4)" "unprognostic (2.67e-1)" "unprognostic (1.94e-4)" "unprognostic (4.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" "unprognostic (5.65e-2)" "unprognostic (7.99e-2)" "unprognostic (8.49e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (5.40e-2)" "unprognostic (7.83e-2)" 0.5 1.2 3.5 6.1 3.2 1.4 5.7 8.7 13.2 8.0 3.2 3.2 2.9 1.2 0.6 2.8 1.1 2.3 1.9 0.4 12.7 8.6 17.0 3.7 0.4 35.4 8.0 1.9 0.7 0.6 3.8 0.2 35.3 2.6 3.2 11.6 2.6 1.0 0.1 4.9 2.5 1.0 2.7 1.6 2.5 5.3 2.6 0.8 9.9 0.0 2.1 9.4 3.4 8.2 0.4 132.5 1.8 0.0 0.9 2.5 0.2 91.3 60.0 65.3 55.8 0.0 2.9 0.0 16.4 98.1 95.4 76.7 0.3 34.5 69.4 0.2 0.7 1.3 1.8 2.0 0.4 0.1 0.2 1.3 3.4 81.1 74.6 5.7 41.2 0.1 0.0 0.7 24.4 0.1 0.0 0.1 2.5 0.0 0.0 0.1 0.9 0.0 52.9 3.6 3.4 4.0 7.5 0.0 0.1 5.0 0.0 0.3 34.7 50.7 15.8 84.4 53.6 0.1 0.0 0.9 28.2 0.1 6.6 0.2 55.3 0.9 0.2 4.7 0.2 0.1 0.1 0.0 12.1 0.1 0.0 0.0 2.0 0.2 0.2 0.2 0.0 14.2 3.5 3.2 8.7 13.2 0.4 12.7 35.4 8.0 35.3 2.7 2.6 8.2 0.1 38.5 2.7 29.7 0.8 26.0 48.0 5.1 21.1 11.0 4.3 18.2 2.0 8.6 7.9 3.7 8.4 0.0 1.3 0.0 9.8 1.8 41.5 0.1 1.9 5.7 0.0 0.0 1466.4 0.2 0.0 10.5 0.0 0.2 1.3 3.2 7.1 5.3 0.5 28.6 411.8 0.0 2.0 10.2 1.9 23.5 0.3 22.1 1.8 36.5 49.2 5.0 0.0 54.3 19.2 0.9 0.0 0.4 0.0 42.9 0.0 18.7 2.4 3.1 0.0 0.1 9.3 11.3 5.0 3.2 6.1 0.0 0.6 0.0 0.0 6.5 NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 366.0;Endothelial cells: 174.4;Hepatic stellate cells: 184.6;Sertoli cells: 282.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 48.6" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.3" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 444.6;hTERT-RPE1: 371.6;TIME: 369.5;U-87 MG: 425.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved "Secreted in other tissues" NA NA 780000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004511: AB_2282634, HPA030278: AB_10601976" "unprognostic (3.19e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (1.50e-2)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (6.17e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.87e-4)" "prognostic unfavorable (1.22e-5)" "unprognostic (3.83e-2)" "unprognostic (5.48e-2)" "unprognostic (7.79e-2)" 125.2 42.3 9.3 43.3 9.4 3.7 62.2 0.0 26.0 36.9 13.3 26.6 21.3 51.6 35.7 19.7 34.5 54.1 80.8 48.6 9.1 52.7 53.1 63.7 23.7 4.0 3.9 43.0 33.0 24.4 9.0 133.7 2.1 21.3 23.6 11.6 19.3 38.4 55.9 22.1 21.0 55.9 5.7 66.7 18.6 12.9 13.4 18.2 49.7 46.6 12.4 35.3 20.0 10.7 57.4 217.8 11.1 1.1 204.8 224.7 1.3 224.4 216.2 109.6 118.2 28.9 132.4 1.1 26.6 444.6 116.8 15.8 13.8 65.2 89.3 0.7 11.2 0.6 24.5 48.7 74.3 20.8 1.6 277.3 11.2 261.7 116.8 371.6 304.0 1.4 0.7 1.4 221.3 96.8 1.4 3.9 5.5 11.9 204.2 9.6 24.8 1.2 109.7 1.3 5.1 2.7 23.0 17.5 0.9 9.2 1.0 3.3 369.5 156.4 36.9 193.0 153.8 0.7 1.1 0.7 425.2 26.4 143.5 0.4 2.5 0.5 0.6 0.4 1.0 0.7 0.7 0.6 2.3 0.6 0.6 0.6 0.4 1.2 0.3 39.3 0.6 0.9 9.3 9.4 0.0 26.0 48.6 9.1 4.0 3.9 2.1 5.7 13.4 10.7 366.0 0.0 20.2 80.3 4.3 15.7 10.6 5.5 7.4 10.5 4.2 5.5 67.6 28.6 13.0 18.4 4.2 61.5 29.4 0.6 1.9 57.9 1.3 11.3 116.9 174.4 4.2 3.2 105.4 18.9 13.4 58.5 6.6 11.0 7.6 62.3 184.6 12.5 135.4 0.0 14.4 1.8 16.2 62.7 33.3 5.5 42.3 46.0 12.4 78.7 5.8 3.4 0.0 11.6 2.3 15.4 0.0 21.1 1.6 4.1 3.0 59.8 5.4 0.9 282.7 13.1 117.9 0.2 1.3 2.7 10.5 67.2 3.8 61.1 1.5 3.3 NTN4 ENSG00000074527 "Netrin 4" Q9HB63 12 95657807-95791189 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 181.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 198.6;Hepatic stellate cells: 369.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "MAIT T-cell: 1.6" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 513.8;hTERT-HME1: 205.8;PC-3: 189.6;TIME: 289.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA049832 Approved "Secreted to extracellular matrix" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA049832: AB_2680905" "unprognostic (3.08e-1)" "unprognostic (2.17e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (2.11e-2)" "unprognostic (1.42e-1)" "unprognostic (1.67e-1)" "unprognostic (3.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (2.85e-1)" "prognostic favorable (8.12e-9)" "unprognostic (3.52e-2)" "unprognostic (7.08e-2)" "unprognostic (1.93e-1)" "prognostic favorable (6.67e-5)" 24.4 17.3 6.4 5.7 7.5 0.1 72.9 4.4 10.5 26.5 12.0 16.5 12.0 12.7 15.3 15.6 34.4 22.4 66.8 8.9 5.7 107.6 26.7 70.2 2.9 5.9 8.7 86.1 62.5 13.3 7.6 11.9 5.7 42.4 18.1 0.6 32.6 59.1 12.6 8.8 17.5 15.0 6.1 181.5 48.7 12.1 6.2 6.2 14.4 19.9 6.5 49.5 14.4 8.7 26.7 71.3 2.0 0.1 28.5 45.0 3.0 49.7 513.8 67.1 78.2 56.1 48.8 0.0 3.5 105.3 88.1 42.2 0.6 15.3 34.0 0.0 4.3 2.3 12.7 11.1 1.7 0.0 0.1 1.1 43.5 75.0 205.8 72.9 133.3 0.4 0.0 0.1 25.4 20.0 0.2 0.3 1.1 7.9 189.6 0.2 0.6 0.1 64.8 133.4 0.3 0.6 60.5 77.1 1.3 2.3 22.2 0.1 289.3 25.9 9.5 101.3 5.2 0.1 0.1 0.0 5.9 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 7.5 4.4 10.5 8.9 5.7 5.9 8.7 5.7 6.1 6.2 8.7 31.9 41.7 123.2 6.2 3.8 4.7 120.5 15.2 39.3 1.8 77.6 55.4 44.8 44.3 30.8 198.6 0.0 6.2 1.3 4.4 5.9 36.7 10.3 36.4 3.2 35.5 0.0 2.7 28.1 28.0 3.6 33.7 23.0 28.1 1.3 25.9 369.5 10.2 0.4 0.0 70.6 37.2 4.1 26.3 3.7 3.8 2.1 2.6 7.2 20.6 0.6 0.3 0.0 112.6 1.8 36.7 4.0 3.4 0.9 108.9 1.5 84.3 38.0 0.2 26.3 119.0 73.9 1.9 0.6 5.9 2.3 1.6 3.3 1.4 6.4 127.0 NTRK3 TRKC ENSG00000140538 "Neurotrophic receptor tyrosine kinase 3" Q16288 15 87859751-88256768 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.8" "Cell type enhanced" "Detected in many" "Astrocytes: 239.3;Early spermatids: 119.6;Excitatory neurons: 360.0;Inhibitory neurons: 277.8;Late spermatids: 148.9;Microglial cells: 177.1;Oligodendrocyte precursor cells: 499.6" "Group enriched" "Detected in some" 4 "glioma: 2.5;testis cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "U-138 MG: 100.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009233, HPA027484, HPA048065" Approved Supported "Nuclear membrane,Nucleoli,Nucleoli rim" NA NA 19000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim" "Nuclear membrane" "CAB009233: AB_632555, HPA027484: AB_2672297, HPA048065: AB_2680245" "unprognostic (1.27e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.65e-1)" "unprognostic (3.34e-1)" "unprognostic (3.18e-2)" "unprognostic (2.23e-2)" "unprognostic (2.34e-1)" "unprognostic (3.91e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-3)" "unprognostic (6.45e-3)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (2.49e-3)" 12.8 3.7 31.3 0.8 33.2 0.1 7.8 30.7 34.3 12.8 0.0 3.4 0.5 10.4 3.2 1.3 15.0 1.6 5.8 38.8 25.8 5.1 1.0 5.3 1.2 21.5 19.6 7.2 1.0 0.1 12.2 1.0 22.1 9.0 2.0 5.2 6.8 4.3 1.8 4.8 2.2 3.7 10.9 2.5 3.2 9.8 33.4 1.2 3.0 1.9 2.0 8.7 7.4 21.5 0.0 13.1 2.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 2.5 0.0 0.0 0.0 2.6 0.1 0.1 0.1 0.7 0.1 0.0 0.0 0.0 0.9 0.1 0.1 0.0 100.6 1.8 0.0 1.3 0.0 0.0 0.0 3.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.3 33.2 30.7 34.3 38.8 25.8 21.5 19.6 22.1 10.9 33.4 21.5 0.5 0.0 0.0 239.3 0.0 0.5 6.4 0.0 0.0 53.8 3.7 6.0 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 119.6 0.4 25.0 1.2 0.0 0.0 360.0 0.0 0.0 5.7 0.0 0.5 0.0 0.0 2.2 0.0 1.0 1.7 277.8 0.0 0.0 0.0 0.6 148.9 3.4 0.6 0.0 177.1 0.0 8.6 0.0 499.6 7.4 0.0 0.0 27.4 0.0 1.3 0.0 0.1 0.0 3.7 52.6 20.3 40.9 11.0 3.7 0.0 0.1 0.1 0.2 0.0 0.0 0.7 OPCML "IGLON1, OBCAM, OPCM" ENSG00000183715 "Opioid binding protein/cell adhesion molecule like" Q14982 11 132414977-133532519 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 39.2;parathyroid gland: 10.3;retina: 11.6" "Group enriched" "Detected in some" 34 "Excitatory neurons: 2120.9;Inhibitory neurons: 1900.4;Oligodendrocyte precursor cells: 3173.2" "Cancer enriched" "Detected in some" 4 "glioma: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "BJ: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 7100000 "Cluster 6: Brain - Smell perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.59e-1)" "unprognostic (2.26e-2)" "unprognostic (3.70e-2)" "unprognostic (3.31e-4)" "unprognostic (8.23e-2)" "unprognostic (3.53e-2)" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (8.46e-3)" "unprognostic (2.59e-2)" "unprognostic (2.80e-1)" "unprognostic (4.73e-2)" "unprognostic (1.11e-2)" "unprognostic (1.13e-2)" "unprognostic (1.76e-1)" "unprognostic (9.71e-2)" "unprognostic (2.19e-1)" 0.2 0.4 13.2 0.1 16.6 0.0 0.1 22.3 39.2 0.4 0.0 0.1 0.1 0.6 0.1 0.4 0.5 0.2 0.3 18.4 3.1 1.4 0.0 0.0 0.0 0.0 5.1 0.3 0.0 10.3 1.3 0.0 0.0 0.1 0.1 11.6 0.2 0.6 0.1 0.1 0.1 0.5 0.2 0.7 0.2 0.4 9.6 0.0 0.1 0.3 0.0 0.1 0.1 13.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 9.4 0.0 1.4 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 16.6 22.3 39.2 18.4 3.1 0.0 5.1 0.0 0.2 9.6 13.4 0.0 0.0 0.0 25.5 0.0 0.1 0.0 0.0 0.0 40.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 6.7 0.0 0.0 0.4 0.0 0.0 2120.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 1.7 1900.4 0.0 0.0 0.3 0.4 14.9 0.0 0.1 0.0 69.3 0.0 1.3 0.0 3173.2 30.3 0.0 0.0 1.2 0.0 0.0 0.0 0.6 0.0 4.2 6.6 0.0 1.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772485-128775794 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "retina: 41.0" "Cell type enriched" "Detected in some" 12 "Cone photoreceptor cells: 41.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "LHCN-M2: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013562, HPA014083" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytokinetic bridge,Cytosol" Yes NA "Cluster 79: Retina - Phototransduction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Cytokinetic bridge, Cytosol" "HPA013562: AB_2668850, HPA014083: AB_2668938" "unprognostic (2.88e-1)" "unprognostic (5.17e-2)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (8.50e-5)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (3.79e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (5.98e-8)" "unprognostic (2.53e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (9.33e-4)" 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 41.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OXTR ENSG00000180914 "Oxytocin receptor" P30559 3 8750381-8769628 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 14.7;breast: 54.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 122.6;Excitatory neurons: 25.8;Oligodendrocyte precursor cells: 21.1;Respiratory ciliated cells: 57.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 421.2;BJ hTERT+: 127.9;BJ hTERT+ SV40 Large T+: 119.4;fHDF/TERT166: 424.5;HBF TERT88: 92.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.18e-1)" "unprognostic (7.94e-2)" "unprognostic (4.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.02e-2)" "unprognostic (2.02e-1)" "unprognostic (1.46e-2)" "unprognostic (2.56e-3)" "unprognostic (2.12e-1)" "unprognostic (3.42e-1)" "unprognostic (2.76e-1)" "unprognostic (3.80e-2)" "unprognostic (4.24e-4)" "unprognostic (8.25e-2)" "unprognostic (4.60e-2)" "unprognostic (2.71e-1)" "unprognostic (1.84e-1)" 0.4 0.2 4.0 0.1 8.1 0.6 54.1 3.3 4.1 0.5 0.3 0.2 0.1 3.5 0.3 1.6 3.0 0.3 0.5 3.1 13.7 0.5 0.2 0.9 0.2 14.7 12.4 3.1 0.1 0.1 0.3 0.5 6.6 0.8 0.1 2.7 0.2 0.8 0.2 0.2 0.2 0.5 12.0 0.3 0.2 0.3 13.7 0.3 0.3 0.1 0.1 0.8 0.2 3.7 1.1 4.6 2.5 0.5 0.5 1.2 0.8 421.2 127.9 119.4 63.4 0.6 11.3 0.3 0.9 424.5 1.7 0.9 2.0 0.9 92.4 3.9 2.1 1.1 1.9 0.7 2.2 1.0 1.0 0.7 0.5 1.7 0.9 36.1 0.2 1.3 0.2 0.8 67.5 0.3 0.9 3.3 2.7 1.4 18.7 0.9 1.6 25.5 4.5 0.4 0.7 0.8 0.7 0.9 0.2 8.1 0.3 0.6 0.6 5.9 1.5 1.2 1.2 0.7 1.2 0.2 0.6 1.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 4.0 8.1 3.3 4.1 3.1 13.7 14.7 12.4 6.6 12.0 13.7 3.7 1.3 9.6 1.1 3.3 0.3 0.4 0.6 1.0 0.0 0.8 2.3 122.6 1.5 1.5 6.5 0.0 0.0 0.2 0.4 0.3 0.0 2.7 1.4 4.7 0.6 0.7 0.0 0.0 25.8 0.0 0.1 2.0 0.0 0.9 0.0 4.3 1.4 0.0 0.2 0.0 14.0 0.0 2.0 0.0 0.0 2.0 0.0 3.1 0.0 5.6 0.1 7.9 0.0 21.1 15.4 1.2 0.1 0.4 0.2 2.2 0.0 0.1 57.1 0.2 0.0 2.0 16.9 1.0 1.8 0.0 0.1 0.0 0.3 3.1 0.1 0.3 P3H1 "GROS1, LEPRE1, LEPRECAN, MGC117314" ENSG00000117385 "Prolyl 3-hydroxylase 1" Q32P28 1 42746335-42767084 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Extravillous trophoblasts: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 193.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012113, HPA016980" Approved Approved Nucleoli,Vesicles "Intracellular and membrane" NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles Nucleoli "HPA012113: AB_2668626, HPA016980: AB_2669498" "unprognostic (3.24e-1)" "unprognostic (1.04e-1)" "unprognostic (9.37e-2)" "unprognostic (4.57e-1)" "unprognostic (2.03e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.95e-7)" "unprognostic (5.41e-2)" "unprognostic (2.70e-3)" "unprognostic (9.16e-2)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" "unprognostic (2.67e-2)" "unprognostic (1.60e-3)" 12.4 11.1 3.6 8.7 3.5 6.1 10.2 3.6 4.4 13.4 7.3 8.3 2.4 13.8 6.1 4.4 9.8 12.0 9.1 3.8 3.8 7.2 13.3 11.6 5.1 5.2 3.5 12.8 6.8 5.9 15.5 37.4 3.8 7.5 5.4 1.3 6.7 5.9 3.0 7.6 7.4 20.3 3.4 11.5 6.7 15.2 3.8 7.6 7.6 3.9 5.1 12.3 8.5 3.6 8.7 22.3 48.7 115.0 112.8 85.4 20.1 101.8 131.9 71.9 121.7 11.3 18.8 13.0 79.7 193.0 29.2 7.8 20.9 25.9 49.2 19.5 26.3 30.5 32.2 32.6 65.2 30.9 34.0 73.8 17.4 72.6 30.9 102.4 102.9 18.3 17.5 16.1 49.0 4.7 20.6 17.8 53.1 4.7 16.0 19.9 71.9 17.7 38.2 4.9 10.2 17.3 62.5 1.7 45.8 85.2 3.7 127.0 85.1 53.8 47.2 43.4 41.2 14.5 17.5 11.9 61.5 41.5 77.0 5.0 18.9 16.8 8.3 20.4 8.8 4.1 6.3 7.0 23.6 3.3 5.1 5.3 1.8 17.8 26.3 10.9 12.4 9.3 3.6 3.5 3.6 4.4 3.8 3.8 5.2 3.5 3.8 3.4 3.8 3.6 13.7 3.2 2.3 5.9 10.5 0.0 6.4 0.0 6.2 10.2 4.5 6.5 5.0 7.2 0.6 11.0 25.0 47.9 11.1 0.4 0.0 11.5 17.1 3.2 30.1 16.4 6.1 11.3 12.9 7.6 56.6 34.4 3.6 4.4 1.3 28.8 16.8 11.3 17.6 15.2 10.8 2.5 0.0 8.7 0.0 10.8 19.3 11.7 0.0 9.4 10.5 3.5 6.2 9.5 6.9 7.4 2.0 16.1 11.2 3.4 1.7 1.9 0.7 22.1 0.0 17.2 22.3 30.6 18.8 3.5 0.0 17.5 9.6 27.0 1.9 4.5 P3H3 "GRCB, HSU47926, LEPREL2" ENSG00000110811 "Prolyl 3-hydroxylase 3" Q8IVL6 12 6828407-6839847 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 19.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 47.2;Cone photoreceptor cells: 100.1;Horizontal cells: 43.7;Leydig cells: 49.7;Peritubular cells: 38.4;Rod photoreceptor cells: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 39.6;hTERT-RPE1: 27.3;NTERA-2: 27.5;U-251 MG: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043695 Approved Approved "Nucleoli,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 740000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Nucleoli "HPA043695: AB_10797146" "unprognostic (2.54e-1)" "unprognostic (6.66e-2)" "unprognostic (1.14e-1)" "unprognostic (3.34e-2)" "unprognostic (5.76e-2)" "unprognostic (6.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.92e-1)" "unprognostic (6.90e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.64e-4)" "unprognostic (2.58e-2)" "unprognostic (9.67e-2)" "unprognostic (2.27e-1)" "unprognostic (7.77e-3)" 3.5 2.6 1.2 1.5 0.7 0.3 3.9 3.7 2.7 11.9 5.6 5.4 0.8 19.2 0.5 1.6 9.9 1.7 4.5 1.1 1.2 2.0 0.6 3.7 0.3 1.3 0.2 12.4 2.9 4.5 15.4 1.3 0.3 6.0 0.3 4.1 6.5 3.7 0.8 3.0 2.8 3.8 0.2 1.3 3.8 1.2 0.9 0.1 4.3 0.3 0.3 7.8 6.4 0.5 0.0 1.6 7.1 14.0 8.4 10.2 0.3 39.6 22.4 12.2 13.5 0.6 0.0 0.0 0.5 14.9 0.5 0.0 4.4 0.4 2.7 0.1 18.8 1.0 4.2 1.9 5.9 1.0 0.0 11.1 0.4 6.0 3.3 27.3 13.1 1.2 3.7 0.0 5.7 0.0 0.1 0.4 27.5 0.0 1.1 0.0 6.9 0.2 0.6 0.0 2.8 10.5 0.1 0.0 4.8 3.4 0.2 0.2 23.2 12.0 17.5 18.6 27.7 0.1 0.3 0.3 10.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 3.7 2.7 1.1 1.2 1.3 0.2 0.3 0.2 0.9 0.5 2.3 0.0 0.0 3.3 0.5 0.0 4.9 0.0 2.2 47.2 5.3 5.5 11.1 1.5 1.8 5.5 100.1 0.5 0.1 0.1 1.9 1.4 0.9 0.9 19.6 3.9 1.2 0.0 13.1 2.7 0.5 24.1 2.0 0.4 0.0 0.8 7.9 0.0 1.4 43.7 13.7 2.7 0.0 0.0 0.0 2.2 49.7 0.5 0.0 2.8 1.1 5.3 0.0 5.5 1.3 1.3 0.1 38.4 3.1 5.1 0.4 0.4 1.5 28.8 6.6 7.8 11.9 0.7 0.8 0.8 0.0 1.0 0.9 3.2 0.6 1.5 P4HA1 "C-P4Halpha(I), P4HA" ENSG00000122884 "Prolyl 4-hydroxylase subunit alpha 1" P13674 10 73007217-73096974 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 494.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007599, HPA026593" Enhanced Supported "Endoplasmic reticulum,Vesicles,Mitochondria" "Intracellular and membrane" Yes No 60000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "Vesicles, Mitochondria" "HPA007599: AB_1854891, HPA026593: AB_1854892" "prognostic unfavorable (9.01e-4)" "prognostic unfavorable (3.19e-5)" "unprognostic (2.76e-3)" "unprognostic (3.04e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (2.30e-1)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.28e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.15e-2)" "prognostic unfavorable (9.40e-9)" "unprognostic (3.14e-1)" "unprognostic (4.22e-2)" "unprognostic (1.02e-2)" "unprognostic (5.75e-2)" 28.1 26.0 25.7 20.8 26.4 15.5 26.3 29.6 58.5 31.9 34.7 16.3 11.0 27.0 18.9 10.1 41.1 26.3 38.7 26.5 27.1 35.8 72.8 27.8 16.2 32.9 30.0 34.9 17.5 17.0 11.6 65.3 33.0 20.0 17.4 33.3 13.0 18.4 110.9 17.4 14.4 28.5 30.2 19.6 19.8 19.3 30.1 12.9 13.9 54.0 14.6 29.6 18.2 39.0 84.0 21.2 60.1 117.6 181.2 138.3 50.1 239.9 215.8 90.8 215.8 35.6 63.6 28.4 89.7 239.0 55.1 92.5 38.3 87.7 197.1 36.5 14.5 24.4 18.6 42.5 75.3 45.1 16.4 84.5 50.3 77.7 101.6 494.2 43.5 23.8 38.3 14.7 79.3 22.4 17.9 42.9 21.6 38.9 92.3 16.4 40.2 52.4 51.0 35.6 5.5 33.7 49.2 143.2 58.3 135.0 21.9 41.9 41.9 110.5 44.8 31.3 56.9 81.8 31.3 13.7 198.1 64.5 54.9 1.1 18.8 14.9 6.7 23.5 8.7 8.2 8.1 7.9 20.7 9.2 5.9 6.1 10.4 5.2 25.7 16.6 10.7 9.1 25.7 26.4 29.6 58.5 26.5 27.1 32.9 30.0 33.0 30.2 30.1 39.0 29.0 6.4 28.4 87.1 31.7 36.3 33.0 138.0 22.2 13.5 23.8 15.7 42.0 7.2 69.2 23.9 27.1 31.5 24.9 25.1 0.0 33.1 16.8 85.6 89.2 25.9 10.3 7.2 48.8 19.5 116.4 67.7 14.3 131.4 40.5 16.9 20.0 29.8 43.9 11.8 41.6 9.5 46.8 54.1 75.7 8.1 51.9 51.5 44.4 62.8 39.0 34.0 6.2 86.5 44.8 36.6 27.1 47.0 32.9 24.9 13.5 25.1 94.6 17.2 39.5 37.0 44.7 61.7 34.0 9.8 23.9 33.2 27.7 31.1 7.0 17.6 P4HA2 C-P4Halpha(II) ENSG00000072682 "Prolyl 4-hydroxylase subunit alpha 2" O15460 5 132190147-132295315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 115.6;Endometrial stromal cells: 96.9;Skeletal myocytes: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HHSteC: 324.2;U-87 MG: 323.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA016997, HPA027824, CAB062557" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" No No 13000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum, Vesicles" "CAB062557: AB_2665641, HPA016997: AB_2669501, HPA027824: AB_2672402" "unprognostic (1.30e-3)" "prognostic unfavorable (1.24e-5)" "unprognostic (2.56e-3)" "unprognostic (1.28e-3)" "unprognostic (2.08e-3)" "unprognostic (1.62e-3)" "unprognostic (1.16e-3)" "unprognostic (1.93e-3)" "unprognostic (2.83e-2)" "unprognostic (1.92e-1)" "unprognostic (8.98e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (2.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.12e-4)" 17.4 11.7 11.9 16.1 12.1 2.4 12.3 11.4 28.4 29.5 42.2 28.7 22.6 31.1 76.7 19.6 29.6 19.9 40.6 14.4 17.2 80.0 10.5 31.5 2.5 11.4 14.3 8.6 70.7 10.9 19.9 35.1 19.1 10.8 32.7 7.8 32.5 17.1 13.0 16.7 26.8 52.6 10.0 8.7 20.5 9.7 16.8 11.3 20.7 22.9 8.3 22.9 22.3 12.2 57.0 34.9 11.2 57.2 149.2 173.7 61.1 261.9 223.7 108.9 265.0 78.9 50.3 1.5 71.8 283.3 120.5 70.2 33.2 136.5 172.7 41.5 11.9 0.6 48.1 49.0 324.2 0.0 33.9 104.6 193.1 128.8 117.4 162.7 59.1 0.1 21.2 3.6 134.0 23.2 0.2 0.5 3.0 53.7 27.2 0.9 3.6 9.8 31.1 11.0 5.4 15.8 67.7 22.3 47.9 84.1 28.4 3.7 88.9 171.7 63.5 51.0 57.1 24.4 28.1 11.8 323.4 0.4 48.3 0.0 0.4 0.0 0.8 0.3 0.7 0.0 0.4 0.1 0.2 0.0 0.0 0.1 1.0 0.9 0.0 0.3 0.0 0.2 11.9 12.1 11.4 28.4 14.4 17.2 11.4 14.3 19.1 10.0 16.8 12.2 13.0 35.3 10.3 7.5 1.1 16.8 43.6 115.6 23.9 11.6 9.5 9.5 13.3 8.6 36.9 11.0 22.9 2.6 0.3 43.2 5.9 68.3 1.4 26.7 96.9 12.2 15.0 0.0 7.7 71.8 70.2 61.6 12.8 28.0 5.7 11.1 9.3 7.8 7.6 0.0 7.7 18.6 32.6 1.3 5.5 2.0 8.1 4.4 30.2 2.8 2.6 6.8 0.0 1.5 1.2 81.9 41.0 5.3 3.0 19.6 41.4 44.6 71.9 5.2 26.3 109.4 47.6 23.0 29.1 6.8 9.8 7.5 4.8 10.4 13.8 15.3 PACS1 "FLJ10209, KIAA1175" ENSG00000175115 "Phosphofurin acidic cluster sorting protein 1" Q6VY07 11 66070272-66244744 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 113.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038914 Approved Approved Microtubules,Cytosol NA NA 17000 "Cluster 46: Basophils - DNA binding" "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Microtubules, Cytosol" "HPA038914: AB_10672831" "unprognostic (7.03e-2)" "unprognostic (3.43e-2)" "unprognostic (9.35e-3)" "unprognostic (1.40e-1)" "unprognostic (3.49e-2)" "unprognostic (1.46e-1)" "unprognostic (3.80e-3)" "unprognostic (1.40e-2)" "unprognostic (3.55e-2)" "unprognostic (1.10e-1)" "unprognostic (2.17e-2)" "unprognostic (3.55e-2)" "unprognostic (1.01e-1)" "unprognostic (2.37e-3)" "unprognostic (5.31e-2)" "unprognostic (5.23e-2)" "unprognostic (3.46e-1)" 30.6 24.0 26.4 33.7 28.4 26.0 26.4 28.4 29.0 30.4 11.0 29.7 13.3 26.7 17.7 32.1 22.2 23.6 45.4 27.2 18.5 28.0 11.4 30.2 49.8 18.2 20.4 32.4 26.8 18.7 21.6 18.9 17.1 34.6 10.2 35.1 92.8 22.2 22.4 27.6 25.6 30.3 13.0 34.9 24.9 42.2 20.7 35.1 34.0 17.2 46.2 33.9 29.6 18.8 44.1 45.6 21.1 13.3 38.5 46.1 23.7 59.3 41.9 40.6 25.2 28.4 34.3 27.6 38.2 102.5 37.7 27.9 15.6 42.7 54.4 43.7 18.3 45.0 41.7 41.2 45.8 6.5 34.6 46.8 19.8 37.0 47.2 78.1 39.8 18.2 16.7 52.2 44.7 83.3 48.1 16.8 9.8 12.0 21.2 31.6 21.5 47.9 28.9 43.4 29.8 33.6 61.5 34.5 29.1 33.9 39.7 8.3 54.4 52.2 23.1 71.9 25.6 26.2 19.1 7.4 45.0 10.4 26.0 3.7 1.3 2.8 3.4 1.0 2.2 2.9 3.1 2.9 1.3 4.8 3.5 3.1 7.4 2.0 2.9 0.8 4.0 3.0 26.4 28.4 28.4 29.0 27.2 18.5 18.2 20.4 17.1 13.0 20.7 18.8 19.9 3.2 3.0 93.7 41.3 10.1 17.6 8.8 16.5 31.4 16.5 16.3 16.9 8.6 12.1 12.9 50.1 8.1 31.9 2.8 5.9 20.5 17.0 11.1 17.3 18.2 6.1 14.1 113.5 62.7 10.9 15.8 13.7 16.3 23.5 80.3 26.0 4.6 13.1 92.5 90.0 2.2 6.1 14.5 14.7 27.6 18.6 22.7 10.6 96.5 33.4 13.9 38.1 87.4 49.2 54.7 1.2 18.0 13.5 23.3 1.0 13.1 11.8 41.2 13.1 12.3 16.5 20.6 21.8 16.5 9.9 5.7 36.3 16.5 3.6 17.0 PAM "PAL, PHM" ENSG00000145730 "Peptidylglycine alpha-amidating monooxygenase" P19021 5 102753981-103031105 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1560.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1406.5;Enteroendocrine cells: 321.4;Inhibitory neurons: 487.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 529.9;fHDF/TERT166: 714.5;hTERT-RPE1: 562.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026119, HPA042260" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA 98000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus, Cytosol" "CAB026119: , HPA042260: AB_2677919" "unprognostic (4.30e-3)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.63e-4)" "unprognostic (4.23e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (7.58e-2)" "unprognostic (6.62e-2)" "unprognostic (2.71e-1)" "unprognostic (9.91e-2)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.08e-1)" "unprognostic (9.79e-2)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" 119.3 202.5 71.6 34.6 81.4 10.1 99.0 50.7 82.5 595.0 96.2 125.1 52.6 140.9 678.2 69.4 87.6 97.3 1560.4 75.2 179.9 116.0 20.1 88.3 27.7 86.5 99.8 136.4 104.4 257.8 137.0 60.0 170.9 91.6 80.4 37.6 205.4 236.5 155.3 66.9 52.1 157.9 55.7 52.5 131.6 22.4 106.0 17.9 95.1 159.4 30.5 103.3 116.1 50.0 111.3 16.3 195.9 87.2 529.9 314.8 78.0 307.6 457.0 89.1 268.9 53.5 143.2 0.1 65.0 714.5 125.7 36.8 11.0 135.3 244.0 13.5 44.7 22.9 60.0 17.7 80.3 7.4 23.9 173.4 57.3 65.6 49.2 562.6 186.8 8.9 0.9 15.0 255.6 22.9 0.1 3.2 35.3 19.7 59.3 8.5 108.9 62.4 346.1 13.0 92.3 63.9 131.2 8.3 83.3 114.0 34.0 7.3 144.9 280.8 72.4 133.3 93.4 33.1 8.6 0.4 322.3 30.8 247.6 4.2 8.0 0.2 20.7 1.5 14.9 0.8 12.3 15.6 3.1 0.4 4.1 6.8 16.6 26.3 3.4 1.6 19.9 10.8 71.6 81.4 50.7 82.5 75.2 179.9 86.5 99.8 170.9 55.7 106.0 50.0 45.7 54.5 39.3 47.0 3.9 28.2 12.0 26.1 12.0 19.1 27.5 12.1 1406.5 0.0 30.4 60.7 2.1 1.6 12.6 13.7 7.9 12.6 8.8 47.6 48.6 63.5 321.4 3.4 229.2 21.5 40.6 220.4 26.0 83.0 9.5 68.3 74.6 3.5 5.9 8.4 487.7 13.8 18.3 10.3 48.3 8.1 60.3 9.3 37.4 192.0 9.5 11.6 22.6 154.8 9.3 30.6 6.3 58.6 12.1 26.4 4.8 43.8 19.2 3.8 19.7 36.4 44.9 2.6 5.6 8.0 23.7 6.7 16.6 19.3 6.3 18.2 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 240.4;Distal enterocytes: 202.4;Hepatocytes: 111.5;Proximal enterocytes: 181.3;Theca cells: 96.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Cell line enhanced" "Detected in many" "BJ: 189.8;fHDF/TERT166: 473.2;HHSteC: 196.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" 33.3 135.2 6.3 26.6 7.0 2.0 20.9 6.2 9.5 17.8 6.2 79.9 29.5 8.5 3.1 10.2 12.4 20.7 11.6 5.8 6.2 23.8 77.0 70.4 11.0 6.9 6.6 27.5 26.1 2.1 3.0 58.5 7.5 6.7 64.3 2.3 16.4 3.4 4.7 3.5 61.8 16.7 6.8 8.5 9.2 11.7 8.0 3.0 21.3 8.7 14.8 16.6 11.5 7.2 19.9 20.0 6.4 0.3 129.4 164.8 0.3 189.8 157.7 110.4 79.9 1.0 4.1 0.1 9.8 473.2 3.5 8.5 13.9 13.3 125.2 0.2 10.0 8.8 13.4 0.1 196.5 0.2 3.8 58.7 0.3 63.7 5.2 135.6 94.2 1.4 0.0 89.4 79.2 74.1 0.1 0.7 7.4 4.8 24.1 0.4 0.1 0.4 117.5 8.7 0.9 1.6 92.5 3.3 1.1 12.6 13.5 5.3 120.0 38.2 22.5 131.5 13.9 0.3 1.0 0.3 18.3 0.2 0.2 0.0 1.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 7.7 0.0 0.0 0.8 6.3 7.0 6.2 9.5 5.8 6.2 6.9 6.6 7.5 6.8 8.0 7.2 49.5 240.4 38.2 3.6 2.6 2.3 0.9 18.0 1.8 0.2 11.5 4.7 4.4 8.6 13.8 9.2 0.0 0.5 0.8 202.4 13.7 6.4 1.2 2.6 18.7 23.2 12.6 5.2 22.2 30.2 0.8 36.1 15.3 11.6 0.0 20.3 36.0 111.5 11.5 0.0 27.6 26.5 4.1 29.8 50.7 0.8 17.4 51.0 1.8 30.0 5.2 1.3 0.0 21.6 1.0 19.4 46.1 5.3 3.1 2.1 181.3 9.8 3.4 0.0 13.1 1.0 20.4 1.2 0.7 1.1 1.3 1.4 1.7 96.4 74.3 1.1 PARP3 "ADPRT3, ADPRTL3, ARTD3, hPARP-3, IRT1, pADPRT-3" ENSG00000041880 "Poly(ADP-ribose) polymerase family member 3" Q9Y6F1 3 51942345-51948867 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020984, HPA067657" Supported Supported "Nucleoplasm,Nuclear bodies" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nuclear bodies" "HPA020984: , HPA067657: AB_2685881" "prognostic favorable (6.39e-5)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (2.85e-2)" "unprognostic (7.31e-2)" "unprognostic (1.56e-1)" "unprognostic (4.13e-1)" "unprognostic (3.53e-2)" "unprognostic (2.26e-1)" "unprognostic (2.01e-1)" "unprognostic (7.44e-3)" "unprognostic (4.30e-1)" "prognostic favorable (1.25e-8)" "unprognostic (5.63e-2)" "unprognostic (1.77e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-3)" 16.0 33.4 12.7 9.9 13.5 3.1 15.3 12.9 14.6 9.6 14.4 17.1 28.1 11.4 5.9 10.4 11.2 11.3 13.6 11.6 14.2 21.2 29.2 13.4 10.9 13.8 14.9 8.9 4.4 35.8 10.9 5.9 13.7 14.6 10.2 4.7 14.5 15.5 15.8 7.5 25.2 9.3 12.9 14.8 16.4 5.4 14.9 8.2 19.6 17.6 8.0 15.4 10.8 12.4 10.0 6.6 2.0 17.3 17.8 30.0 4.8 15.4 29.0 23.1 24.9 3.9 28.1 14.1 4.5 29.4 12.6 1.6 5.0 14.5 9.1 34.8 1.2 7.8 15.1 13.2 18.8 5.3 10.9 24.4 12.4 16.2 9.1 35.7 10.8 10.2 3.5 14.7 19.9 3.4 4.6 12.5 2.4 4.2 16.4 7.3 2.8 13.9 14.0 13.5 2.0 6.4 16.3 4.8 10.7 1.4 6.5 5.9 24.0 42.5 9.9 7.4 10.4 22.5 26.0 6.0 27.2 14.4 13.6 0.0 1.6 1.2 2.4 3.0 2.2 6.3 2.6 1.8 2.6 2.5 3.6 3.5 0.1 5.7 1.6 0.9 3.2 1.8 12.7 13.5 12.9 14.6 11.6 14.2 13.8 14.9 13.7 12.9 14.9 12.4 5.3 6.4 10.0 6.2 8.1 2.7 10.6 15.9 21.1 2.0 8.6 8.9 7.4 8.6 8.6 0.0 0.0 0.6 2.1 13.1 7.9 9.7 7.8 2.4 3.8 5.3 3.0 1.7 2.6 6.3 0.4 4.7 17.3 2.7 4.5 0.8 2.5 9.5 3.7 0.0 3.0 11.3 6.1 3.2 2.2 15.3 4.7 3.7 7.2 3.7 5.0 3.8 0.0 1.0 1.8 11.5 6.5 1.5 4.9 4.3 33.4 20.6 9.5 2.1 6.6 4.1 5.7 3.4 3.3 7.8 1.4 0.5 5.9 1.6 13.8 9.3 PARVA "FLJ10793, FLJ12254, MXRA2" ENSG00000197702 "Parvin alpha" Q9NVD7 11 12377563-12535356 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cell shape, Chemotaxis, Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 229.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005964 Approved Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA 7300000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Actin filaments, Focal adhesion sites" Cytosol "HPA005964: AB_1079569" "unprognostic (3.87e-2)" "unprognostic (7.38e-2)" "unprognostic (3.30e-2)" "prognostic favorable (1.76e-4)" "unprognostic (7.37e-3)" "unprognostic (1.38e-2)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.76e-2)" "unprognostic (2.80e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-2)" "unprognostic (6.73e-2)" "unprognostic (6.58e-3)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.82e-2)" 61.8 17.6 9.3 22.7 9.0 0.1 40.9 7.2 10.1 53.9 16.5 92.4 17.5 71.8 16.7 42.8 38.8 31.9 34.3 9.8 11.6 23.0 16.9 28.8 6.4 11.0 7.3 31.9 36.0 16.9 11.7 35.9 8.4 50.6 38.4 8.9 20.9 68.9 8.1 14.0 26.1 95.5 11.3 11.3 42.5 6.8 8.6 4.6 17.9 11.7 9.1 55.0 28.2 11.0 34.0 33.1 30.2 39.4 147.8 110.6 69.1 126.5 130.1 87.7 81.6 24.7 51.8 0.0 41.1 229.5 9.9 20.7 0.4 66.4 104.0 0.6 14.9 0.1 42.4 18.7 114.7 0.1 0.9 91.3 22.3 37.1 57.4 107.5 110.9 0.0 0.1 0.3 131.8 20.4 0.0 0.2 14.2 20.2 26.4 0.0 75.2 0.2 44.9 32.8 4.8 0.1 97.6 39.1 65.5 66.9 18.4 0.9 138.2 105.1 43.8 57.2 35.4 0.1 0.1 0.2 58.5 0.1 118.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 9.0 7.2 10.1 9.8 11.6 11.0 7.3 8.4 11.3 8.6 11.0 37.0 99.3 33.0 47.3 1.1 13.8 25.0 29.3 20.5 4.3 24.4 24.8 45.1 18.6 27.0 27.6 0.0 39.9 0.7 39.6 39.2 56.1 0.9 26.9 62.5 33.3 27.1 0.0 31.4 67.1 92.2 59.1 24.5 35.9 5.1 34.8 39.7 19.1 6.5 0.0 34.9 26.2 18.3 1.8 8.8 2.5 41.0 2.0 46.2 36.5 1.0 25.3 0.0 30.7 1.0 51.7 25.4 51.9 0.2 33.5 23.1 38.1 54.8 2.5 52.6 32.6 60.6 1.1 3.4 20.2 8.9 19.0 2.3 25.1 32.4 25.1 PCDHB16 "KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a" ENSG00000272674 "Protocadherin beta 16" Q9NRJ7 5 141182387-141186226 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 14.9;Endometrial stromal cells: 10.0;Fibroblasts: 7.3;Horizontal cells: 8.4;Skeletal myocytes: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 19.4;LHCN-M2: 10.5;U-138 MG: 39.3;U-2197: 11.1;U-87 MG: 9.9" "Low region specificity" "Detected in all" HPA014668 Approved "Vesicles,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA014668: AB_1855055" "unprognostic (3.44e-3)" "unprognostic (4.03e-2)" "unprognostic (8.14e-2)" "unprognostic (8.60e-2)" "unprognostic (2.78e-2)" "unprognostic (1.36e-2)" "unprognostic (1.17e-1)" "unprognostic (4.03e-2)" "unprognostic (3.13e-2)" "unprognostic (7.55e-3)" "unprognostic (3.49e-2)" "unprognostic (9.57e-2)" "unprognostic (3.55e-2)" "unprognostic (7.49e-3)" "unprognostic (2.00e-2)" "unprognostic (7.92e-3)" "unprognostic (2.83e-3)" 3.1 1.9 1.2 1.2 0.9 0.2 2.4 2.1 1.8 2.6 0.0 1.6 0.5 4.5 4.8 0.7 2.2 2.0 2.5 1.6 0.8 2.0 1.0 2.4 0.6 2.0 1.0 6.7 1.9 4.3 2.3 1.2 1.2 1.7 0.9 2.2 1.8 0.9 1.0 1.3 0.9 2.7 1.5 1.1 0.9 1.4 1.3 0.4 1.7 3.3 0.2 1.6 1.5 2.2 0.1 0.3 1.0 19.4 7.8 5.2 0.6 0.8 3.8 0.0 0.3 0.1 0.3 0.0 5.0 0.9 2.1 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.2 0.1 0.1 0.0 0.0 3.3 0.1 0.2 0.1 2.0 10.5 0.4 0.0 0.1 1.5 0.0 0.2 0.1 2.8 0.0 0.6 0.2 0.7 2.6 0.3 0.6 3.9 0.5 7.9 0.0 0.6 39.3 1.7 11.1 2.7 0.1 0.1 0.0 9.9 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 1.2 0.9 2.1 1.8 1.6 0.8 2.0 1.0 1.2 1.5 1.3 2.2 6.4 3.2 1.5 0.0 0.0 0.8 0.1 1.0 0.0 14.9 1.2 2.4 1.9 5.7 0.6 1.8 0.0 0.0 0.0 0.0 1.9 0.8 1.2 0.6 10.0 4.8 1.8 0.0 0.0 4.7 0.0 7.3 0.5 0.4 0.0 0.2 2.2 0.1 0.1 8.4 0.0 0.0 4.1 0.3 0.9 1.5 4.7 0.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.7 0.0 5.7 0.1 0.1 0.0 0.7 0.2 1.6 0.0 7.6 5.9 2.9 0.3 0.5 1.4 0.0 0.2 0.4 0.0 0.0 PCDHGA12 "CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12" ENSG00000253159 "Protocadherin gamma subfamily A, 12" O60330 5 141430507-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enhanced" "Detected in some" "Adipocytes: 2.2;Bipolar cells: 3.8;Cardiomyocytes: 1.6;Endometrial stromal cells: 2.3;Endothelial cells: 2.2;Fibroblasts: 3.2;Skeletal myocytes: 2.0" "Group enriched" "Detected in many" 5 "glioma: 1.7;melanoma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cell line enhanced" "Detected in some" "BJ: 9.3;BJ hTERT+: 15.4;fHDF/TERT166: 23.3;HHSteC: 7.2;HSkMC: 16.5;TIME: 7.5" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 21000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.17e-3)" "unprognostic (2.71e-2)" "unprognostic (1.04e-2)" "unprognostic (2.67e-1)" "unprognostic (2.74e-1)" "unprognostic (5.06e-2)" "unprognostic (1.99e-1)" "unprognostic (9.01e-3)" "unprognostic (1.19e-1)" "unprognostic (4.65e-4)" "unprognostic (2.98e-1)" "unprognostic (3.02e-1)" "unprognostic (1.28e-4)" "unprognostic (8.30e-3)" "unprognostic (1.57e-1)" "unprognostic (2.42e-1)" "unprognostic (6.85e-3)" 3.0 4.3 5.3 0.8 6.8 0.0 1.5 5.5 3.7 2.0 0.8 1.3 0.2 2.6 0.4 1.0 1.9 3.9 4.2 5.1 8.4 1.0 0.7 3.1 0.4 10.0 4.2 1.9 1.1 0.3 1.4 2.2 4.5 1.0 0.3 1.4 0.9 1.5 1.3 1.7 0.8 1.7 5.5 1.2 1.0 0.3 5.2 0.9 1.6 1.1 0.4 1.2 2.0 4.6 0.0 0.0 0.1 1.9 0.8 1.4 0.1 9.3 15.4 0.0 0.0 0.0 0.0 0.5 0.0 23.3 0.1 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.2 0.0 0.0 16.5 0.0 4.5 0.0 0.0 5.4 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 2.6 7.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.3 6.8 5.5 3.7 5.1 8.4 10.0 4.2 4.5 5.5 5.2 4.6 2.2 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 3.8 0.2 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.3 2.2 0.0 0.0 0.0 0.2 0.0 3.2 1.1 0.1 0.0 0.1 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.7 0.0 2.0 1.0 0.0 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 PCDHGB4 "CDH20, FIB2, PCDH-GAMMA-B4" ENSG00000253953 "Protocadherin gamma subfamily B, 4" Q9UN71 5 141387698-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Horizontal cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 43.3;SuSa: 15.5;TIME: 22.7" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.33e-1)" "unprognostic (1.83e-3)" "unprognostic (2.91e-1)" "unprognostic (1.18e-1)" "unprognostic (1.23e-2)" "unprognostic (9.25e-3)" "unprognostic (2.20e-1)" "unprognostic (1.25e-2)" "unprognostic (1.99e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (2.70e-2)" "unprognostic (2.62e-1)" "unprognostic (1.13e-1)" "unprognostic (3.27e-2)" 1.3 1.1 1.3 0.4 1.5 0.0 0.9 4.4 1.4 1.5 1.8 1.1 0.2 1.6 1.5 0.7 1.3 0.5 1.5 2.0 3.2 1.4 1.6 1.1 0.1 2.0 2.0 2.4 1.0 1.9 1.2 3.0 1.5 1.2 0.4 1.4 1.6 1.4 1.0 1.7 0.5 1.0 1.4 0.4 0.4 0.5 2.5 0.7 1.7 0.8 0.2 1.0 1.1 1.5 0.0 1.1 11.1 0.1 6.9 8.5 1.3 10.8 43.3 4.4 3.0 0.0 0.0 0.4 8.3 0.3 0.2 3.3 0.0 0.0 4.6 0.0 0.0 0.0 0.2 2.4 2.8 0.0 0.0 8.4 0.1 4.1 0.0 0.1 6.7 0.0 0.4 0.1 0.0 0.0 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.4 0.0 15.5 5.6 4.2 22.7 6.0 1.8 0.3 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 1.5 4.4 1.4 2.0 3.2 2.0 2.0 1.5 1.4 2.5 1.5 0.2 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.6 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 PCNX4 "C14orf135, PCNXL4" ENSG00000126773 "Pecanex 4" Q63HM2 14 60091911-60169133 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 42.8;Endometrial ciliated cells: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002076, HPA003390" Uncertain Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA002076: AB_1078322, HPA003390: AB_2066703" "unprognostic (2.00e-1)" "unprognostic (1.45e-1)" "unprognostic (1.89e-1)" "unprognostic (9.87e-2)" "unprognostic (2.18e-1)" "unprognostic (2.94e-1)" "unprognostic (3.83e-3)" "unprognostic (2.01e-1)" "unprognostic (1.54e-1)" "unprognostic (3.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.81e-1)" "prognostic favorable (6.84e-5)" "unprognostic (2.13e-1)" "unprognostic (2.08e-1)" "unprognostic (4.14e-2)" "unprognostic (8.59e-2)" 7.8 9.2 4.1 6.3 4.8 7.4 8.1 7.0 4.4 10.1 12.1 6.3 5.0 12.5 7.1 5.6 13.1 8.3 11.1 3.9 6.1 12.3 6.7 7.2 7.1 5.0 6.0 16.3 6.5 11.4 11.9 8.5 4.7 11.7 6.7 18.2 7.1 8.5 12.3 7.4 6.1 10.2 4.9 7.4 6.2 11.0 5.7 11.6 9.7 5.7 7.0 6.6 7.8 6.2 85.2 14.3 25.2 17.3 19.2 22.2 11.1 28.5 44.1 31.2 38.3 15.0 26.1 14.8 11.6 23.7 26.0 11.1 16.6 16.2 51.7 20.8 7.9 25.0 10.1 9.7 39.7 25.0 17.7 18.5 10.2 23.0 38.3 24.3 14.9 34.8 12.5 21.2 48.2 11.5 35.9 8.0 12.7 9.7 17.4 20.9 31.8 6.4 15.8 11.7 17.9 21.8 25.5 9.2 18.2 13.4 22.7 11.1 30.7 66.4 52.8 16.7 20.5 7.1 7.4 19.6 26.1 8.5 33.2 3.4 4.1 3.3 4.8 4.3 6.5 4.1 3.4 4.2 4.4 2.8 3.7 4.4 2.1 8.4 5.2 4.4 3.8 3.4 4.1 4.8 7.0 4.4 3.9 6.1 5.0 6.0 4.7 4.9 5.7 6.2 22.3 16.0 29.9 0.0 18.2 0.0 0.0 0.0 0.0 0.0 19.9 17.5 0.0 0.0 19.2 25.8 0.0 18.3 42.8 0.0 17.6 18.4 0.0 82.0 37.4 14.0 0.0 0.0 0.0 13.1 8.3 13.6 0.0 27.0 15.2 33.9 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 10.3 0.0 0.0 0.0 0.0 20.4 0.0 0.0 18.5 0.0 0.0 14.4 34.2 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 19.4 14.5 33.8 0.0 0.0 PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 17.9;Langerhans cells: 13.1;Microglial cells: 12.2;monocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 71.4;BJ hTERT+: 111.6;HDLM-2: 88.1;TIME: 49.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" 4.4 0.8 0.4 6.9 0.6 0.3 4.3 0.5 0.5 2.5 0.3 1.7 0.7 2.2 1.2 2.0 2.4 3.4 2.7 0.4 0.8 1.2 4.2 7.1 10.4 1.1 0.6 1.6 0.6 0.4 0.2 4.8 1.1 1.0 2.1 0.0 1.3 1.4 1.5 1.4 1.5 3.1 0.9 15.1 1.4 0.6 0.7 5.0 1.0 2.2 6.2 4.2 2.2 1.3 6.0 0.0 0.0 0.0 4.7 5.4 0.1 71.4 111.6 33.7 40.4 0.0 0.3 0.0 0.2 29.2 4.8 0.5 0.1 9.7 33.3 88.1 0.0 0.0 0.0 0.0 26.5 0.0 0.0 5.0 0.1 15.8 18.5 9.7 22.4 0.0 0.0 8.5 41.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.7 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.0 0.1 49.7 24.0 1.4 11.8 20.1 1.2 0.1 0.1 13.6 0.0 3.0 1.5 0.3 0.0 0.5 1.4 0.6 0.2 0.7 0.3 0.3 0.1 0.0 0.3 0.7 0.0 0.1 0.0 1.1 0.3 0.4 0.6 0.5 0.5 0.4 0.8 1.1 0.6 1.1 0.9 0.7 1.3 6.1 6.4 0.5 1.6 0.4 1.0 0.1 0.7 1.8 0.0 0.2 1.5 0.1 0.0 0.7 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.0 1.6 0.2 17.9 6.7 0.5 0.0 3.8 0.2 6.8 0.0 2.9 0.0 1.4 0.0 0.0 5.3 13.1 0.0 5.9 2.5 1.8 12.2 26.4 0.0 0.0 1.0 2.4 3.7 0.0 2.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 2.2 3.1 0.0 0.0 0.3 1.0 0.8 1.1 0.1 0.0 0.1 PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32428131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 68.9;heart muscle: 58.5" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 1071.4" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.4;fHDF/TERT166: 148.3;hTERT-RPE1: 44.9;U-251 MG: 77.9;WM-115: 105.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052375 Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA052375: AB_2681802" "unprognostic (1.29e-2)" "unprognostic (2.20e-5)" "unprognostic (1.68e-2)" "unprognostic (1.20e-3)" "unprognostic (2.29e-1)" "unprognostic (5.65e-2)" "unprognostic (4.06e-3)" "unprognostic (2.75e-1)" "unprognostic (6.79e-3)" "unprognostic (6.49e-2)" "unprognostic (3.88e-5)" "unprognostic (7.03e-2)" "unprognostic (3.09e-3)" "unprognostic (5.76e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-3)" 2.4 1.8 19.2 2.5 43.0 0.0 4.3 21.4 39.9 0.7 0.0 3.0 1.4 2.4 6.0 6.4 10.5 1.5 58.5 18.9 24.2 4.2 0.1 4.9 0.6 29.4 27.9 3.8 2.6 0.3 1.3 3.2 27.7 2.0 1.8 7.4 1.8 3.2 0.6 0.4 3.3 5.0 16.4 0.6 4.0 3.8 28.6 1.6 3.1 4.0 0.1 9.8 1.4 68.9 0.3 5.8 15.5 0.0 0.6 0.4 0.2 44.4 18.3 20.8 17.1 0.0 0.0 0.0 0.2 148.3 0.0 1.2 0.0 0.0 27.1 0.0 0.0 1.3 1.4 0.0 0.1 0.0 31.9 1.9 0.0 4.3 0.2 44.9 7.1 0.0 0.1 0.1 1.7 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 0.0 22.5 0.0 6.8 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.2 22.8 8.6 0.4 77.9 0.4 0.0 0.0 2.4 0.5 105.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 43.0 21.4 39.9 18.9 24.2 29.4 27.9 27.7 16.4 28.6 68.9 1.2 0.0 0.0 7.5 0.1 0.0 0.7 0.1 1.2 69.5 2.8 17.1 136.0 0.0 0.7 1.8 52.1 0.0 0.1 0.0 0.0 4.8 53.4 0.2 0.1 3.9 0.0 0.0 70.8 0.4 0.0 8.7 0.0 0.4 8.8 0.2 0.0 0.0 0.1 3.3 169.2 0.0 59.0 0.0 0.2 50.3 0.3 0.5 0.0 15.9 0.0 0.9 0.0 196.6 1071.4 0.2 0.0 0.4 0.1 0.2 0.0 0.0 2.2 4.7 0.0 0.9 9.4 1.3 1.2 0.2 0.0 0.0 0.1 1.2 0.0 0.0 PDE5A ENSG00000138735 "Phosphodiesterase 5A" O76074 4 119494397-119628804 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 66.1;Inhibitory neurons: 58.3;Oligodendrocyte precursor cells: 56.8;Peritubular cells: 104.9;Smooth muscle cells: 80.9" "Group enriched" "Detected in all" 4 "prostate cancer: 7.0;thyroid cancer: 27.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 47.5;HHSteC: 65.9;hTERT-RPE1: 24.6" "Region enhanced" "Detected in all" "cerebellum: 18.2" "Low region specificity" "Detected in all" "HPA004729, HPA012873" Approved Approved Cytosol NA NA 850000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA004729: AB_1079588, HPA012873: AB_1855124" "unprognostic (6.95e-2)" "prognostic favorable (5.20e-4)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (7.36e-2)" "unprognostic (2.58e-2)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.16e-2)" "unprognostic (1.52e-2)" "unprognostic (8.98e-2)" "unprognostic (8.71e-3)" "prognostic unfavorable (1.17e-4)" 15.4 11.3 0.9 10.9 3.5 2.1 9.6 4.9 3.7 32.7 12.6 37.0 15.5 14.4 41.5 41.3 22.9 10.4 12.8 1.4 3.6 5.9 1.5 22.1 6.4 4.9 8.2 5.4 12.4 8.3 3.5 13.2 5.2 59.8 25.9 9.6 9.8 49.8 6.9 5.0 18.9 11.4 0.0 5.8 9.6 9.4 3.4 3.7 16.8 5.6 3.5 14.6 15.8 1.9 16.7 0.8 11.0 1.2 3.7 5.5 1.9 10.7 47.5 0.5 1.0 1.0 1.3 1.6 0.5 13.4 3.0 5.8 3.5 1.7 1.3 0.4 7.4 18.5 2.6 0.9 65.9 3.9 1.7 6.1 3.3 1.1 0.1 24.6 1.4 3.7 2.0 2.9 1.6 0.9 5.0 0.6 2.3 1.8 2.8 0.7 5.9 4.3 4.1 4.9 4.3 8.8 13.0 15.3 1.3 8.1 2.7 2.1 2.5 6.2 5.2 3.4 1.5 4.1 2.0 1.5 5.9 1.0 0.9 0.0 0.0 0.0 0.1 0.0 0.5 0.4 0.3 0.1 0.0 0.3 0.1 0.2 0.4 0.2 0.1 0.1 0.1 1.2 0.9 3.5 4.9 3.7 1.4 3.6 4.9 8.2 5.2 0.0 3.4 1.9 7.8 6.4 3.9 19.9 1.3 3.4 2.8 1.1 5.7 8.1 11.0 8.4 5.5 14.3 3.7 1.8 14.6 0.4 0.9 15.5 0.0 15.8 30.6 5.0 12.6 7.8 2.4 0.0 66.1 2.9 0.3 28.1 1.1 3.9 1.3 1.6 0.7 0.9 0.3 5.0 58.3 9.5 2.0 0.0 3.5 11.5 20.8 11.3 5.4 40.3 1.3 28.5 2.1 56.8 41.1 3.9 10.3 104.9 1.4 3.6 7.9 0.5 0.8 5.8 19.7 5.5 80.9 5.4 6.3 3.5 2.4 0.3 1.7 7.0 11.1 2.6 PDGFC "fallotein, SCDGF" ENSG00000145431 "Platelet derived growth factor C" Q9NRA1 4 156760454-156971799 "Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 98.6;Granulosa cells: 124.1;Microglial cells: 85.3;Oligodendrocyte precursor cells: 233.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 60.0;hTERT-RPE1: 56.8;U-138 MG: 41.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009134 Approved Supported "Plasma membrane,Cytosol" "Secreted to blood" NA NA 37000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "HPA009134: AB_10601981" "unprognostic (3.12e-1)" "unprognostic (1.91e-2)" "unprognostic (5.79e-2)" "unprognostic (3.67e-2)" "unprognostic (3.97e-1)" "unprognostic (3.41e-2)" "unprognostic (8.78e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (8.12e-2)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" "prognostic favorable (1.35e-5)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.25e-1)" "unprognostic (1.19e-2)" "prognostic unfavorable (3.17e-4)" 4.8 4.0 0.9 1.3 1.0 0.6 7.5 0.4 1.0 9.2 0.7 2.3 2.0 9.9 2.1 3.3 6.7 4.8 2.6 1.0 0.8 5.5 5.1 3.1 1.1 0.8 0.7 7.7 4.3 20.3 0.4 4.5 0.7 8.7 2.0 0.7 8.4 7.0 1.2 1.6 2.8 9.4 0.9 1.3 2.8 0.9 1.1 2.0 6.5 1.2 1.0 3.2 1.2 1.0 2.5 3.7 38.6 25.4 7.0 13.4 1.0 21.5 21.5 12.0 16.1 2.2 9.4 0.0 3.8 60.0 9.2 2.6 10.8 13.4 16.5 0.0 5.0 25.5 3.2 2.4 18.3 3.9 0.3 14.2 6.6 30.6 21.7 56.8 6.0 0.1 0.1 0.1 30.2 0.1 0.0 0.0 0.4 0.0 1.7 0.0 8.1 0.0 22.5 0.9 0.0 0.0 0.0 0.2 0.4 6.0 3.1 1.3 28.3 41.7 0.4 10.9 17.3 0.0 0.0 0.0 16.1 0.0 1.6 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.9 1.0 0.4 1.0 1.0 0.8 0.8 0.7 0.7 0.9 1.1 1.0 2.4 6.4 14.2 98.6 0.7 49.6 22.7 12.4 25.0 2.0 14.7 13.6 16.8 58.6 7.8 12.9 0.0 0.6 3.4 0.5 0.0 15.4 30.5 6.9 15.0 7.3 0.0 5.5 64.4 7.1 0.3 18.6 8.2 11.4 1.3 124.1 10.0 15.9 13.0 0.0 32.1 2.1 4.1 34.4 21.6 23.8 5.3 32.1 10.6 85.3 14.2 6.3 0.0 233.2 3.0 18.0 0.5 23.0 1.4 8.7 2.4 18.6 3.5 0.5 6.6 34.8 18.2 0.7 2.9 3.4 13.5 0.5 0.9 13.8 2.1 4.8 PDLIM2 ENSG00000120913 "PDZ and LIM domain 2" Q96JY6 8 22578279-22598025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 793.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "white matter: 429.2" "Low region specificity" "Detected in many" HPA003880 Approved Supported "Actin filaments,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Actin filaments, Focal adhesion sites" "HPA003880: AB_1855149" "unprognostic (1.04e-1)" "unprognostic (3.53e-2)" "unprognostic (1.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-3)" "unprognostic (9.33e-2)" "unprognostic (3.69e-2)" "unprognostic (4.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.22e-3)" "unprognostic (1.52e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.37e-7)" "unprognostic (6.14e-2)" "unprognostic (8.17e-2)" "unprognostic (3.47e-2)" "unprognostic (3.08e-3)" 66.0 31.6 40.6 31.9 42.2 23.7 51.0 51.0 56.6 85.1 42.6 86.9 60.9 80.2 9.8 131.4 56.0 52.8 51.4 36.9 43.9 77.7 59.4 88.8 54.4 56.6 52.9 49.6 53.7 9.8 35.3 40.5 59.4 45.5 11.2 2.0 48.6 30.9 201.9 153.1 64.3 23.2 49.9 232.0 38.8 12.2 49.9 20.4 27.4 60.9 24.4 57.5 91.7 54.8 90.3 54.5 36.2 63.9 69.9 118.5 40.9 139.1 102.4 97.6 98.5 62.4 14.7 36.9 38.4 126.4 18.1 44.7 20.5 95.0 19.0 0.1 14.1 11.6 35.2 46.1 88.2 13.0 85.9 127.2 11.6 48.2 13.2 76.8 54.2 20.2 3.3 23.4 67.4 46.5 16.7 15.4 29.8 37.8 5.5 13.3 6.9 3.9 17.3 18.3 11.3 26.9 29.1 78.1 128.7 21.3 27.5 25.8 68.2 105.7 108.6 127.9 64.8 0.4 0.8 12.5 109.0 51.3 79.6 78.2 48.0 162.3 47.0 64.4 42.2 25.0 35.5 46.9 38.4 27.6 23.8 35.4 101.6 28.1 63.8 24.7 40.7 34.6 40.6 42.2 51.0 56.6 36.9 43.9 56.6 52.9 59.4 49.9 49.9 54.8 85.8 76.9 13.1 5.5 45.0 95.1 12.9 48.1 39.9 3.0 34.0 42.5 10.2 18.6 34.2 18.4 0.0 73.1 70.9 92.0 15.6 24.9 1.0 8.8 94.0 48.7 1.2 10.5 3.2 26.1 115.1 98.9 7.7 13.8 27.3 25.7 86.4 49.4 59.0 3.3 2.3 12.6 20.3 59.1 73.8 3.4 132.0 37.9 48.0 8.4 42.5 33.1 122.6 7.1 3.9 93.2 126.1 218.2 6.8 52.7 217.6 146.3 5.2 3.6 59.2 27.1 108.3 0.7 6.3 39.7 100.7 793.0 71.6 21.0 15.0 30.6 PDLIM7 ENIGMA ENSG00000196923 "PDZ and LIM domain 7" Q9NR12 5 177483394-177497606 "Predicted intracellular proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 570.3;skeletal muscle: 661.5" "Cell type enhanced" "Detected in many" "Ductal cells: 164.8;Exocrine glandular cells: 242.1;Pancreatic endocrine cells: 320.1;Peritubular cells: 223.0;Sertoli cells: 164.3;Smooth muscle cells: 157.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 177.1;eosinophil: 121.2;neutrophil: 438.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 438.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018794, HPA048815" Approved Enhanced "Actin filaments,Focal adhesion sites" NA NA 1700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Actin filaments, Focal adhesion sites" "HPA018794: AB_1855155, HPA048815: AB_2680530" "unprognostic (7.70e-3)" "unprognostic (3.75e-2)" "unprognostic (9.27e-3)" "prognostic unfavorable (5.45e-4)" "unprognostic (1.40e-1)" "unprognostic (3.48e-2)" "unprognostic (9.18e-3)" "prognostic unfavorable (4.07e-4)" "unprognostic (5.01e-2)" "unprognostic (3.10e-1)" "unprognostic (7.24e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (6.19e-10)" "unprognostic (6.72e-3)" "unprognostic (3.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.68e-2)" 74.3 26.7 23.0 74.5 27.2 50.3 58.2 18.8 39.8 183.7 30.2 570.3 31.5 489.5 28.8 64.5 236.0 45.0 79.9 22.3 27.6 52.8 16.0 84.7 15.1 23.9 23.4 94.2 15.1 9.6 66.3 33.2 24.9 245.3 24.9 5.7 42.3 200.7 661.5 38.0 111.7 177.6 20.8 84.5 156.1 37.6 28.5 11.5 37.1 70.5 7.6 315.4 125.0 20.5 115.8 25.8 120.7 89.4 32.5 59.9 118.9 232.4 132.8 128.9 89.0 50.9 109.6 20.4 220.4 156.4 69.5 59.5 19.7 160.6 30.3 27.5 27.6 73.6 92.2 52.6 83.6 38.8 237.3 132.0 29.1 115.6 51.5 191.9 85.4 18.3 52.4 15.3 102.5 103.9 7.0 88.6 75.7 23.2 108.8 144.4 101.3 14.0 89.1 29.6 17.5 35.8 91.5 16.9 44.6 39.9 24.3 31.3 292.9 153.8 168.1 60.5 211.7 4.0 4.7 24.1 73.3 44.2 35.7 177.1 46.7 121.2 5.3 22.9 6.3 9.6 3.1 7.2 26.7 5.3 3.0 4.0 438.7 2.3 29.3 1.9 7.0 23.9 23.0 27.2 18.8 39.8 22.3 27.6 23.9 23.4 24.9 20.8 28.5 20.5 36.6 0.0 0.6 11.1 7.5 14.5 47.1 106.8 6.2 6.3 7.6 65.3 21.0 4.3 20.9 25.8 14.6 12.5 4.4 5.5 25.4 164.8 27.0 7.5 44.8 51.0 3.5 9.4 13.9 242.1 53.3 65.0 9.7 7.3 17.2 18.6 51.0 1.6 64.0 8.4 7.4 2.1 36.7 16.6 18.3 49.3 44.7 44.9 10.6 5.6 31.0 16.2 1.0 2.0 1.7 320.1 33.6 223.0 3.2 30.4 1.0 15.7 13.2 22.6 164.3 24.6 157.7 11.6 38.7 12.2 15.8 14.1 10.8 18.2 3.1 25.3 PEA15 "HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15" ENSG00000162734 "Proliferation and apoptosis adaptor protein 15" Q15121 1 160205380-160215376 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1106.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 246.3;monocytes: 267.6;Muller glia cells: 315.8" "Cancer enhanced" "Detected in all" "glioma: 466.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 78.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028356, HPA070820" Enhanced Supported Nucleoplasm,Cytosol NA NA 300000 "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol Nucleoplasm "HPA028356: AB_10602814, HPA070820: AB_2732166" "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (1.64e-2)" "unprognostic (1.99e-3)" "unprognostic (6.10e-2)" "unprognostic (4.57e-1)" "unprognostic (1.25e-1)" "unprognostic (6.31e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (6.53e-7)" "unprognostic (2.60e-2)" "unprognostic (1.39e-1)" "unprognostic (2.82e-3)" "unprognostic (1.24e-1)" 190.2 82.2 863.3 121.7 900.6 16.6 142.7 908.1 949.4 110.1 612.5 146.5 31.7 124.5 83.4 119.2 104.2 88.2 241.9 884.6 939.2 112.0 41.2 147.9 75.5 1028.2 1010.2 80.4 39.6 85.4 80.0 102.3 981.5 112.2 58.5 461.4 80.8 119.4 61.1 105.6 64.8 194.6 933.0 103.2 75.8 80.5 915.2 40.7 83.5 84.5 96.9 133.4 110.2 1106.4 139.2 46.8 190.5 82.5 344.5 191.5 63.6 593.2 503.3 471.6 328.5 103.7 72.3 63.4 210.9 729.4 226.6 146.4 71.5 181.7 365.3 34.4 40.2 52.4 32.5 26.7 423.9 17.8 62.0 161.8 100.7 260.2 328.5 259.6 360.7 45.7 55.1 111.8 640.6 68.3 21.0 41.1 127.0 160.9 134.3 34.4 200.6 43.8 173.0 71.0 38.0 100.0 310.4 207.6 179.9 409.4 128.1 122.6 487.7 311.3 246.4 234.4 254.5 88.1 59.5 118.7 287.1 33.2 450.8 1.3 39.3 5.2 8.4 78.2 6.5 18.9 6.2 6.9 56.7 13.5 3.8 4.2 1.8 7.9 38.7 25.0 7.9 14.9 863.3 900.6 908.1 949.4 884.6 939.2 1028.2 1010.2 981.5 933.0 915.2 1106.4 137.8 16.0 29.9 40.5 38.6 80.2 124.2 21.8 33.6 172.1 76.9 60.2 246.3 11.5 24.7 5.5 73.0 21.8 13.7 12.7 29.4 74.7 65.4 36.4 33.7 125.1 12.0 7.4 24.8 46.3 61.1 81.5 17.9 85.9 31.1 17.2 89.3 6.5 63.3 92.5 19.1 12.0 8.2 42.6 234.6 55.4 66.8 68.9 74.7 14.0 267.6 315.8 8.2 12.1 48.3 102.5 4.7 109.9 14.8 119.4 5.4 18.3 13.8 129.2 46.0 69.4 78.3 16.5 4.1 42.7 73.3 45.3 19.4 18.5 12.8 178.8 PEAK1 "KIAA2002, sgk269" ENSG00000173517 "Pseudopodium enriched atypical kinase 1" Q9H792 15 77100656-77420144 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Excitatory neurons: 162.1;Oligodendrocyte precursor cells: 513.2;Oligodendrocytes: 338.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.8" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.8" "Cell line enhanced" "Detected in all" "TIME: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026313, HPA026517" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "HPA026313: AB_1856801, HPA026517: AB_1856802" "unprognostic (1.15e-1)" "unprognostic (2.89e-1)" "unprognostic (1.05e-1)" "unprognostic (4.20e-1)" "unprognostic (6.26e-2)" "unprognostic (8.82e-2)" "unprognostic (6.63e-3)" "unprognostic (1.90e-1)" "unprognostic (2.42e-2)" "unprognostic (6.00e-3)" "unprognostic (1.06e-1)" "unprognostic (9.75e-2)" "unprognostic (2.25e-3)" "unprognostic (5.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.33e-1)" "unprognostic (5.65e-3)" 13.8 4.4 8.9 5.8 13.3 9.1 9.5 5.5 8.8 11.3 1.0 7.8 5.9 7.4 6.4 5.2 5.7 10.0 16.2 8.2 8.4 5.0 3.8 18.0 6.8 6.4 7.8 7.5 4.8 5.4 2.9 16.7 5.8 6.0 8.1 13.7 5.5 7.3 6.7 6.7 7.3 9.9 4.9 29.4 4.9 9.9 11.8 4.7 6.3 8.5 4.7 9.0 7.5 11.7 5.4 7.8 18.1 4.3 33.4 35.7 6.3 28.6 19.7 14.9 14.9 6.3 4.7 4.1 5.0 41.4 5.7 2.6 14.6 4.5 16.9 4.2 7.6 7.7 12.2 3.8 12.2 4.6 3.9 27.6 4.3 28.8 4.8 16.3 42.3 6.6 10.0 4.0 16.1 2.2 2.6 4.9 8.4 3.7 2.1 5.3 10.8 3.0 4.4 9.6 4.0 4.9 11.2 2.3 18.6 19.7 1.7 3.2 52.1 31.5 15.2 13.2 12.2 6.3 9.5 5.9 5.5 10.5 17.3 0.1 0.2 0.4 0.2 0.0 0.4 0.3 0.0 0.0 0.1 0.2 0.1 0.1 0.1 1.8 0.1 0.2 0.0 0.2 8.9 13.3 5.5 8.8 8.2 8.4 6.4 7.8 5.8 4.9 11.8 11.7 48.3 147.4 46.8 101.9 12.6 21.9 7.5 5.6 2.2 18.4 6.1 5.8 46.9 10.0 29.2 1.8 12.5 3.1 12.3 23.9 0.0 6.9 15.1 22.9 19.5 41.2 3.0 10.8 162.1 5.4 2.0 35.6 15.8 10.1 17.7 6.3 31.8 6.0 18.9 20.2 84.4 11.9 2.0 21.3 34.7 13.6 19.9 20.2 12.4 124.6 8.5 28.1 10.3 513.2 338.1 9.8 10.7 16.1 7.0 8.3 15.7 3.7 41.6 20.1 13.1 23.0 37.7 13.6 13.7 5.8 18.0 6.3 8.2 22.6 12.3 7.2 PFDN1 PFD1 ENSG00000113068 "Prefoldin subunit 1" O60925 5 140245035-140303113 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006499 Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" Nucleoli "HPA006499: AB_1079596" "unprognostic (2.73e-1)" "unprognostic (1.48e-1)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (6.11e-2)" "unprognostic (5.66e-3)" "prognostic unfavorable (8.81e-5)" "unprognostic (2.12e-2)" "unprognostic (2.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (4.10e-1)" "unprognostic (8.60e-3)" "unprognostic (2.53e-1)" "unprognostic (3.53e-2)" "unprognostic (3.00e-1)" 74.1 50.9 73.9 37.7 75.6 60.2 50.0 82.2 88.4 41.4 70.8 59.2 40.2 50.8 54.3 52.3 41.9 35.7 93.3 77.2 79.7 61.6 38.5 46.9 46.1 82.9 77.2 37.2 34.7 52.8 39.4 50.8 80.5 44.8 42.9 35.1 45.4 43.7 149.0 46.2 39.8 61.4 79.1 36.6 40.7 29.9 79.3 51.5 42.4 86.4 51.6 45.9 40.9 81.2 172.4 79.6 137.7 80.9 89.7 91.8 133.8 229.6 114.9 174.6 192.6 172.1 107.9 114.9 224.1 124.3 180.0 62.6 102.0 228.7 204.2 122.6 102.9 102.4 76.5 113.0 105.1 213.5 76.4 98.2 119.8 148.5 156.3 112.6 196.0 132.8 93.7 73.1 149.8 78.5 146.0 147.6 92.0 70.3 119.2 101.3 195.9 86.3 197.1 77.9 78.2 81.8 172.1 148.6 136.8 128.5 102.1 122.3 249.1 121.8 119.6 71.9 208.0 70.3 198.6 299.2 122.5 138.5 144.1 149.5 84.7 130.3 86.2 131.1 91.8 106.0 98.6 100.4 100.5 97.9 97.3 88.4 14.0 114.7 130.3 93.0 129.3 115.5 73.9 75.6 82.2 88.4 77.2 79.7 82.9 77.2 80.5 79.1 79.3 81.2 87.9 67.3 33.0 16.3 57.4 38.0 65.9 96.2 30.7 42.5 50.1 57.3 81.3 52.9 62.1 66.2 45.9 116.1 53.1 56.6 123.3 121.9 3.9 58.0 56.6 73.8 46.6 62.9 31.2 101.7 86.6 55.4 35.2 70.9 54.4 53.6 72.1 56.9 85.4 25.2 29.3 43.6 48.8 61.1 37.7 12.9 52.2 63.4 74.7 37.5 90.4 84.9 71.1 24.1 39.3 128.9 55.1 52.3 35.5 45.4 80.9 147.3 45.3 42.9 65.7 39.6 63.7 23.7 61.8 40.8 34.9 85.6 45.2 42.9 47.3 63.6 PGA5 ENSG00000256713 "Pepsinogen A5" P0DJD9 11 61241175-61251444 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2014 "stomach 1: 39870.8" "Cell type enriched" "Detected in some" 77 "Exocrine glandular cells: 4383.1" "Cancer enriched" "Detected in some" 12 "stomach cancer: 15.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 29 "classical monocyte: 1.8;intermediate monocyte: 4.3;non-classical monocyte: 2.4" "Lineage enriched" "Detected in single" 44 "monocytes: 4.3" "Cell line enriched" "Detected in some" 19 "BJ hTERT+: 28.8" HPA046875 Supported "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "HPA046875: AB_2679851" "unprognostic (1.36e-3)" "unprognostic (2.98e-2)" "unprognostic (5.83e-3)" "unprognostic (2.11e-1)" "unprognostic (4.22e-1)" "unprognostic (4.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "unprognostic (7.10e-2)" 19.7 4.4 0.3 1.1 0.3 0.0 4.5 0.1 0.6 4.0 0.0 6.2 0.6 1.9 0.0 7.0 5.1 0.1 3.5 0.7 0.0 2.4 7.0 5.4 0.0 0.1 0.0 2.6 8.2 0.0 3.8 0.5 0.1 1.8 0.1 1.5 2.5 0.5 1.9 2.1 2.1 0.9 0.0 3.9 39870.8 2.3 0.0 0.2 3.1 0.2 0.1 2.3 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.3 0.3 0.3 0.1 0.6 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 4383.1 0.0 0.1 56.6 0.0 0.0 0.2 0.0 0.0 6.7 0.0 0.0 0.0 0.0 5.1 0.0 1.6 0.9 1.3 0.0 0.0 1.0 25.1 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PGAM1 "PGAM-B, PGAMA" ENSG00000171314 "Phosphoglycerate mutase 1" P18669 10 97426191-97433444 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 791.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042528, HPA060483" Approved Supported Nucleoplasm NA NA 120000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "HPA042528: AB_2678039, HPA060483: AB_2684292" "prognostic unfavorable (2.04e-4)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.64e-1)" "unprognostic (5.64e-2)" "unprognostic (1.16e-1)" "unprognostic (9.47e-3)" "unprognostic (7.60e-3)" "unprognostic (1.74e-3)" "unprognostic (3.22e-1)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "unprognostic (2.48e-2)" "unprognostic (1.48e-1)" "unprognostic (5.74e-2)" "unprognostic (4.94e-2)" "unprognostic (1.19e-1)" "unprognostic (2.61e-3)" 149.0 294.7 228.7 153.6 249.7 180.0 122.1 252.9 265.0 184.3 275.1 162.9 151.5 153.7 98.6 436.7 117.2 106.6 275.7 256.1 266.0 167.6 182.5 121.7 165.7 241.7 242.7 133.3 81.8 191.3 150.8 156.6 280.9 107.3 141.9 420.7 164.7 156.5 56.5 206.9 141.4 177.9 228.3 139.6 133.2 87.5 278.8 124.9 86.9 70.2 229.7 186.6 233.3 224.7 1160.6 538.9 364.0 697.9 336.7 307.7 494.1 722.4 938.4 830.2 1148.3 589.4 335.4 609.1 482.7 619.2 333.4 706.8 639.8 1051.4 998.1 567.2 611.7 393.6 386.4 667.5 248.4 570.0 503.9 303.2 422.5 552.7 408.7 1118.9 610.8 447.2 262.0 334.0 884.8 478.3 514.7 697.8 559.0 331.8 637.8 384.2 333.6 484.0 646.0 431.1 79.1 370.1 388.6 229.2 381.2 564.9 625.0 472.9 463.8 441.5 385.2 394.8 844.0 499.0 593.1 556.1 1023.3 937.5 209.3 242.5 433.5 572.7 217.0 366.6 192.3 134.8 183.8 216.9 309.7 114.7 117.5 164.9 312.6 149.4 422.7 110.5 265.6 580.2 228.7 249.7 252.9 265.0 256.1 266.0 241.7 242.7 280.9 228.3 278.8 224.7 92.9 44.8 44.4 23.8 122.2 187.0 173.1 394.2 124.1 403.5 77.8 76.7 22.9 85.8 140.8 106.7 77.2 495.8 122.3 233.9 358.1 321.8 15.1 50.2 113.7 145.9 48.1 71.1 29.4 205.8 791.9 146.0 68.8 72.0 103.4 109.5 96.8 193.7 395.1 387.0 35.7 116.7 152.5 170.0 129.1 27.0 149.5 174.6 131.6 16.9 376.9 404.4 174.0 14.1 19.9 295.7 132.9 234.3 254.9 175.2 283.0 274.8 72.1 300.5 203.8 73.1 199.9 38.0 114.7 253.3 204.7 372.6 138.0 257.8 176.4 269.6 PGM3 "AGM1, DKFZP434B187, PAGM" ENSG00000013375 "Phosphoglucomutase 3" O95394 6 83161150-83193936 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004998, HPA029759, HPA029760" Enhanced Approved Nucleoplasm,Cytosol NA NA 220000 "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Cytosol" "CAB004998: AB_425591, HPA029759: AB_10600305, HPA029760: AB_10601109" "prognostic unfavorable (8.78e-4)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.45e-2)" "unprognostic (3.03e-2)" "unprognostic (1.51e-2)" "unprognostic (4.04e-2)" "unprognostic (1.09e-3)" "unprognostic (6.72e-3)" "unprognostic (3.11e-1)" "prognostic favorable (9.96e-4)" "unprognostic (4.00e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.39e-7)" "unprognostic (2.21e-1)" "unprognostic (7.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.22e-3)" 23.6 21.0 12.0 18.1 12.9 9.3 18.0 20.2 15.2 24.4 19.6 18.0 15.8 17.1 34.5 12.3 13.4 24.6 14.3 9.7 10.5 13.6 38.3 16.8 11.2 10.9 10.2 22.7 46.1 13.3 28.2 47.5 13.1 51.0 23.4 26.8 35.8 20.3 6.7 10.9 18.2 18.5 6.6 11.5 24.9 32.3 11.1 8.2 25.6 8.6 15.2 19.0 12.3 15.9 35.1 23.4 41.8 51.0 68.9 72.9 48.9 118.1 82.9 55.2 83.3 60.1 16.1 18.3 24.7 112.3 53.0 20.1 38.4 49.5 104.6 14.6 37.8 22.7 41.9 105.0 77.6 22.6 11.2 46.2 40.1 96.6 120.0 55.5 64.6 12.1 74.9 19.6 61.0 39.1 3.7 14.7 18.8 31.8 31.6 16.2 92.5 11.3 42.0 36.0 16.9 26.3 34.8 28.5 20.9 61.8 27.0 25.5 94.2 38.3 21.2 74.9 60.5 36.5 16.1 13.0 29.7 17.7 58.4 10.8 4.1 2.7 2.6 3.5 3.9 4.6 2.8 3.4 3.6 2.5 4.5 4.7 1.8 3.5 4.5 4.2 2.1 2.3 12.0 12.9 20.2 15.2 9.7 10.5 10.9 10.2 13.1 6.6 11.1 15.9 14.3 28.9 27.7 14.4 13.0 15.8 29.2 28.5 5.7 16.4 19.9 15.0 6.8 15.7 36.1 11.0 10.4 32.4 12.7 15.9 7.9 31.7 67.7 17.0 35.1 13.8 16.1 6.9 25.1 49.6 71.1 46.1 23.9 36.4 5.1 25.4 14.3 32.6 17.6 8.4 29.4 35.5 18.3 6.0 8.7 20.9 33.5 8.6 10.6 15.9 10.1 25.9 2.1 41.2 36.8 37.9 19.7 18.4 44.1 56.5 16.1 23.2 22.2 21.1 6.6 22.1 26.6 75.5 34.2 11.6 15.6 64.4 10.1 12.2 17.6 25.6 PHACTR2 "C6orf56, KIAA0680" ENSG00000112419 "Phosphatase and actin regulator 2" O75167 6 143536845-143831185 "Predicted intracellular proteins" "Actin-binding, Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "choroid plexus: 164.2;placenta: 83.8" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 214.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 82.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031719, HPA031720, HPA031725" Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA031719: AB_10696055, HPA031720: AB_10670553, HPA031725: AB_10610279" "unprognostic (3.25e-3)" "unprognostic (1.07e-1)" "unprognostic (4.39e-2)" "unprognostic (5.25e-2)" "unprognostic (1.90e-2)" "unprognostic (8.38e-2)" "unprognostic (3.19e-2)" "unprognostic (9.92e-2)" "unprognostic (7.46e-2)" "unprognostic (3.61e-2)" "unprognostic (2.49e-1)" "unprognostic (2.80e-1)" "prognostic favorable (1.99e-4)" "unprognostic (3.60e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-2)" "unprognostic (1.17e-1)" 11.6 25.4 7.0 7.8 9.0 7.6 5.5 4.3 5.7 8.1 164.2 8.5 7.5 9.9 3.6 22.0 5.7 8.4 12.4 10.0 4.9 5.9 7.9 15.7 7.8 12.3 10.3 6.5 4.9 13.1 4.0 83.8 15.1 10.3 8.5 2.7 6.0 6.9 4.5 2.7 6.1 9.8 3.5 13.5 12.0 6.5 16.5 2.7 15.5 7.3 6.7 7.6 6.4 4.5 21.9 13.5 3.6 26.6 3.7 8.0 15.3 18.0 27.2 7.7 9.6 23.9 9.5 1.2 47.5 51.7 5.4 6.5 2.0 17.9 9.1 18.1 8.5 35.5 14.7 14.0 6.1 9.1 10.5 11.2 9.8 7.7 24.9 11.8 47.0 6.7 10.2 0.1 12.4 24.0 1.3 2.1 26.8 7.7 3.8 3.3 26.3 0.2 9.3 19.2 5.2 5.2 20.0 26.1 0.3 13.4 9.8 13.1 82.2 34.9 18.2 15.2 11.8 0.2 0.1 0.3 8.6 9.5 3.2 6.0 3.5 6.7 3.3 2.5 12.3 0.4 4.0 4.4 3.3 0.2 2.4 1.6 1.8 3.5 2.7 3.2 5.5 1.9 7.0 9.0 4.3 5.7 10.0 4.9 12.3 10.3 15.1 3.5 16.5 4.5 160.9 214.7 94.5 41.4 11.7 24.2 16.0 19.5 47.3 37.0 14.2 13.8 71.8 32.9 73.2 22.0 2.1 84.7 27.5 58.9 13.7 30.5 10.1 49.6 43.7 158.6 21.6 32.8 55.2 22.5 49.8 144.8 54.6 64.7 38.7 34.9 157.1 27.6 35.4 101.0 133.8 19.2 24.4 121.1 40.2 23.2 103.2 52.5 24.9 77.8 71.7 10.3 15.5 5.5 20.9 49.4 22.3 120.0 10.6 63.3 20.2 24.8 51.1 3.0 98.6 95.9 83.5 3.1 2.3 33.0 17.2 52.5 51.3 127.9 26.3 30.9 PHF13 MGC43399 ENSG00000116273 "PHD finger protein 13" Q86YI8 1 6613731-6624030 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026830 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA026830: AB_1855288" "unprognostic (6.59e-3)" "unprognostic (7.71e-2)" "unprognostic (2.62e-2)" "unprognostic (9.17e-2)" "unprognostic (1.65e-1)" "unprognostic (8.41e-2)" "prognostic unfavorable (6.86e-4)" "unprognostic (9.84e-3)" "unprognostic (2.62e-1)" "unprognostic (1.59e-1)" "unprognostic (8.73e-3)" "unprognostic (1.40e-2)" "unprognostic (1.68e-3)" "unprognostic (1.58e-1)" "unprognostic (3.86e-2)" "unprognostic (6.68e-2)" "unprognostic (1.05e-1)" 11.5 8.9 7.9 4.7 7.6 9.5 11.4 7.0 8.5 18.5 7.2 16.5 5.2 17.1 10.1 15.1 15.2 10.5 8.3 8.0 8.6 7.7 12.3 10.0 6.2 8.4 8.0 14.1 10.0 9.8 9.9 7.9 7.4 11.4 3.4 6.2 9.6 10.5 10.0 14.4 7.7 8.0 7.4 7.0 9.6 34.0 9.4 8.7 8.8 6.9 5.8 12.3 14.4 8.8 19.2 8.9 25.8 31.8 13.0 17.7 15.1 29.0 21.2 22.5 20.4 17.7 18.2 17.2 11.1 22.2 13.9 15.9 17.1 18.6 22.1 22.9 22.3 26.3 14.3 15.1 13.6 7.0 16.9 19.8 7.9 21.6 10.1 24.9 14.0 16.0 31.7 12.1 19.4 21.3 16.4 19.8 19.1 10.1 15.3 27.7 20.3 9.3 12.2 9.8 18.3 22.7 12.4 21.5 19.1 17.7 17.2 13.4 14.9 39.1 19.1 16.3 14.3 25.2 26.1 29.0 21.6 18.0 8.5 2.3 1.3 4.6 2.4 1.2 3.6 1.5 3.0 2.3 1.3 1.4 2.0 2.4 4.1 2.8 2.0 1.2 2.5 2.3 7.9 7.6 7.0 8.5 8.0 8.6 8.4 8.0 7.4 7.4 9.4 8.8 11.8 3.2 5.0 8.5 8.9 37.5 18.0 7.8 62.0 7.2 23.9 14.7 5.6 5.7 4.5 3.7 0.0 11.4 8.1 4.3 9.8 6.2 7.9 11.5 17.6 10.2 7.8 12.0 3.0 3.7 12.2 15.1 4.6 14.3 5.1 9.6 8.2 9.5 4.3 18.5 3.9 4.2 2.0 4.1 19.1 7.4 10.5 5.0 16.0 1.9 4.5 10.6 1.0 3.0 5.0 5.8 2.2 7.9 8.0 17.5 3.6 4.6 5.4 6.0 26.3 12.1 15.1 14.7 33.2 41.1 40.2 21.2 9.5 8.4 2.8 12.0 PHLPP2 "KIAA0931, PHLPPL, PPM3B" ENSG00000040199 "PH domain and leucine rich repeat protein phosphatase 2" Q6ZVD8 16 71637835-71724701 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.0;retina: 32.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 104.3;Distal enterocytes: 75.5;Excitatory neurons: 69.5;Proximal enterocytes: 73.7;Rod photoreceptor cells: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040761, HPA041837, HPA048598" Approved Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoplasm, Cytokinetic bridge, Mitotic spindle" "HPA040761: , HPA041837: , HPA048598: AB_2680459" "unprognostic (5.67e-2)" "unprognostic (2.00e-1)" "unprognostic (2.29e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.22e-1)" "unprognostic (3.43e-1)" "unprognostic (1.97e-4)" "unprognostic (3.08e-2)" "unprognostic (8.85e-3)" "unprognostic (6.41e-2)" "unprognostic (4.92e-2)" "unprognostic (8.46e-3)" "unprognostic (8.27e-2)" 4.2 2.8 6.6 2.8 7.5 6.5 2.7 5.8 7.4 3.5 0.1 11.7 11.1 3.7 2.9 1.4 3.2 2.4 2.8 7.8 4.8 3.4 3.0 3.1 3.5 4.6 3.9 4.2 3.1 4.5 4.0 2.7 4.7 2.7 12.2 32.2 1.7 3.4 1.9 1.8 22.0 4.5 0.6 2.5 2.4 6.8 5.3 1.9 6.6 2.6 3.2 3.3 2.4 5.1 6.0 7.8 8.3 9.3 6.5 7.8 4.8 8.8 8.0 12.5 10.1 7.2 1.9 11.8 3.4 14.6 9.0 12.4 12.1 4.5 16.1 4.2 6.5 3.3 7.3 4.8 5.1 2.9 5.0 5.8 2.5 17.7 5.7 5.2 4.7 4.1 3.0 3.2 8.7 12.7 3.9 2.3 6.5 1.9 2.1 6.3 7.3 3.9 5.9 4.5 7.2 3.8 18.9 5.1 3.1 6.4 6.3 1.6 6.5 12.5 9.0 5.3 7.4 7.1 5.4 11.9 7.7 2.3 2.8 0.2 0.1 0.0 0.2 0.1 0.2 0.5 0.1 0.3 0.1 0.3 0.2 0.2 0.2 0.7 0.1 0.5 0.3 0.1 6.6 7.5 5.8 7.4 7.8 4.8 4.6 3.9 4.7 0.6 5.3 5.1 4.0 9.6 2.2 26.1 7.4 9.3 5.1 3.5 7.4 20.6 6.9 5.6 3.3 0.0 3.6 3.7 104.3 4.3 3.8 75.5 0.0 2.7 12.0 2.9 6.1 5.3 6.0 22.9 69.5 2.3 0.4 7.7 1.1 5.1 10.2 11.3 2.9 4.1 1.5 23.5 45.9 6.7 4.1 7.0 12.7 6.3 5.3 2.7 14.2 10.3 3.2 6.5 1.0 30.7 32.7 2.5 31.4 5.3 4.0 8.2 73.7 5.1 3.1 68.6 6.6 7.8 7.9 31.6 20.4 1.9 9.1 1.4 4.9 1.7 9.2 2.2 PHTF2 DKFZp434D166 ENSG00000006576 "Putative homeodomain transcription factor 2" Q8N3S3 7 77798792-77957503 "Predicted membrane proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 112.7;tongue: 57.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 109.1;Inhibitory neurons: 94.6;Oligodendrocyte precursor cells: 91.5;Oligodendrocytes: 144.4" "Cancer enhanced" "Detected in all" "testis cancer: 16.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 25.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012312 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA012312: AB_2668649" "unprognostic (1.96e-1)" "unprognostic (2.60e-3)" "unprognostic (4.04e-1)" "unprognostic (1.44e-1)" "unprognostic (5.70e-2)" "unprognostic (1.99e-3)" "unprognostic (5.36e-3)" "unprognostic (2.81e-2)" "unprognostic (1.63e-2)" "unprognostic (1.41e-2)" "unprognostic (3.86e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (3.09e-7)" "unprognostic (8.28e-3)" "unprognostic (2.28e-1)" "prognostic unfavorable (2.78e-4)" "unprognostic (5.53e-2)" 7.9 4.8 3.7 13.1 4.6 12.3 7.1 5.0 6.3 8.7 2.7 6.0 4.0 8.7 5.2 8.6 5.4 10.7 13.0 4.6 3.8 5.7 6.3 7.6 18.1 4.1 3.2 8.2 4.5 26.3 4.6 11.0 3.7 6.7 6.6 7.2 5.0 8.0 112.7 6.8 8.0 11.9 3.9 12.8 4.4 10.0 3.9 9.1 6.5 57.7 17.6 11.7 5.8 7.2 34.6 15.5 20.9 42.6 17.8 19.5 17.3 59.6 54.1 34.9 39.3 26.6 27.3 31.0 4.8 46.4 37.8 27.9 30.1 15.5 49.3 20.9 24.0 12.7 16.7 7.8 19.3 16.9 33.5 11.6 14.5 20.4 30.4 22.4 12.6 17.1 21.0 53.1 37.7 21.7 14.0 10.9 18.9 9.6 18.2 13.8 42.3 25.4 9.6 45.9 20.0 27.9 33.4 37.5 21.9 30.5 39.7 13.0 12.9 59.7 31.9 34.0 35.5 24.9 31.1 38.3 18.9 26.7 52.5 14.1 2.7 4.6 1.8 11.7 3.7 8.2 5.6 1.7 2.8 5.3 1.7 1.8 1.6 5.1 25.4 1.2 8.2 2.7 3.7 4.6 5.0 6.3 4.6 3.8 4.1 3.2 3.7 3.9 3.9 7.2 12.8 6.4 15.2 31.6 54.0 15.9 20.9 9.0 21.1 8.7 13.2 10.0 23.8 14.3 10.8 7.3 12.5 13.7 18.4 8.9 0.0 4.4 27.4 8.1 20.9 9.6 5.4 8.4 109.1 6.7 8.6 18.3 7.7 12.5 39.2 26.7 18.9 5.7 11.7 3.3 94.6 6.6 22.4 32.7 32.6 4.5 12.2 39.7 10.6 47.8 11.1 4.7 10.3 91.5 144.4 5.7 5.6 13.5 34.8 9.0 2.3 2.2 9.7 9.0 13.1 15.1 15.3 47.6 39.2 14.4 17.8 14.8 54.2 14.7 4.8 21.5 PIP5K1A ENSG00000143398 "Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha" Q99755 1 151197949-151249536 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029366 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "HPA029366: AB_10602116" "unprognostic (1.05e-1)" "unprognostic (2.36e-2)" "unprognostic (8.64e-2)" "unprognostic (7.94e-3)" "unprognostic (1.17e-1)" "unprognostic (3.28e-2)" "unprognostic (1.26e-2)" "unprognostic (3.01e-1)" "unprognostic (8.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.16e-7)" "unprognostic (1.44e-1)" "unprognostic (8.14e-2)" "unprognostic (2.93e-1)" "unprognostic (1.59e-1)" 20.1 19.1 16.0 16.1 17.3 9.7 19.5 17.8 19.2 18.9 20.8 17.2 16.2 18.8 21.1 20.4 18.9 19.7 19.8 16.8 17.3 21.9 18.6 21.8 18.7 15.1 15.7 18.7 13.6 23.0 21.5 25.9 14.7 16.7 15.1 30.1 16.9 14.1 29.2 21.0 16.9 20.3 14.2 19.0 16.6 35.1 16.9 24.7 18.4 25.4 20.1 20.5 17.4 18.4 49.3 37.4 57.7 67.6 37.5 38.8 56.7 63.5 89.3 116.6 103.7 68.7 46.8 43.9 66.8 67.9 52.7 42.0 75.7 42.6 101.2 68.8 54.0 36.0 48.4 33.9 70.1 64.9 43.8 51.1 40.3 72.7 90.7 52.1 48.8 69.4 35.6 36.7 60.4 69.9 63.6 32.4 86.0 38.2 58.3 60.5 50.7 34.1 61.2 27.1 38.6 49.4 87.1 66.6 57.4 96.4 69.2 59.4 47.4 46.6 64.7 42.6 77.0 50.5 93.6 99.3 44.7 18.6 56.6 0.1 3.9 5.7 3.7 4.7 2.8 6.6 3.3 4.1 6.4 3.0 3.7 2.9 8.9 3.9 3.8 6.7 3.1 4.7 16.0 17.3 17.8 19.2 16.8 17.3 15.1 15.7 14.7 14.2 16.9 18.4 11.6 32.1 12.2 43.8 21.3 66.2 23.2 17.0 39.9 34.1 31.3 22.0 18.4 17.2 15.3 31.3 98.0 25.9 18.3 12.7 9.8 13.5 4.9 64.0 26.2 15.6 6.0 12.4 59.6 8.7 29.3 19.8 19.4 71.0 12.0 19.9 14.3 14.3 12.8 26.9 51.2 9.7 18.3 10.7 29.5 4.8 13.4 14.9 12.4 44.0 12.2 12.5 9.2 54.8 64.0 19.4 8.9 10.9 16.8 20.9 21.0 10.1 18.4 43.0 13.1 17.4 20.9 52.1 24.6 38.4 50.0 63.5 15.9 18.4 10.7 39.4 PKD2 "Pc-2, PC2, PKD4, TRPP2" ENSG00000118762 "Polycystin 2, transient receptor potential cation channel" Q13563 4 88007635-88077777 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Potassium transport, Transport, Wnt signaling pathway" "Calcium channel, Ion channel, Potassium channel, Voltage-gated channel" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 129.1;Inhibitory neurons: 148.6;Microglial cells: 95.5;Oligodendrocyte precursor cells: 178.9;Oligodendrocytes: 219.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 137.2;BJ hTERT+: 207.1;fHDF/TERT166: 166.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004544, HPA015794, HPA055297" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" Cytosol "CAB004544: AB_672377, HPA015794: AB_1855437, HPA055297: " "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (1.22e-1)" "unprognostic (6.83e-2)" "unprognostic (9.71e-2)" "unprognostic (1.97e-1)" "unprognostic (3.17e-2)" "unprognostic (1.88e-1)" "unprognostic (8.64e-2)" "unprognostic (1.08e-1)" "unprognostic (6.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.17e-3)" "unprognostic (3.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.12e-2)" "unprognostic (2.51e-1)" 30.7 24.2 9.6 13.9 12.2 10.7 18.6 10.0 12.0 40.0 7.3 32.5 10.7 61.1 14.7 12.7 39.3 26.9 19.7 9.0 8.9 48.6 15.0 22.2 11.5 10.4 11.2 47.7 14.8 27.9 9.0 24.5 10.0 23.3 13.2 14.0 9.7 39.2 5.8 10.3 14.8 53.7 9.1 10.9 20.0 10.3 11.9 7.6 16.4 11.7 8.7 20.6 18.4 14.6 7.4 40.8 44.9 23.2 101.8 67.6 13.3 137.2 207.1 62.9 62.2 2.0 12.8 4.0 29.3 166.4 24.0 9.1 8.1 20.4 54.5 21.2 7.1 6.6 21.8 4.3 56.5 16.2 12.9 56.4 9.1 49.4 26.4 85.6 28.8 7.6 0.9 10.9 55.5 14.4 11.4 7.7 23.4 5.3 6.7 21.5 26.8 6.0 55.6 17.2 9.0 20.1 25.5 1.2 32.5 45.0 9.7 12.1 44.7 59.1 12.9 16.8 18.8 8.7 2.9 4.4 35.2 2.5 55.3 1.4 0.1 0.2 0.2 0.2 0.4 0.1 0.2 0.1 0.0 0.1 0.2 0.1 0.2 0.3 0.1 0.4 0.1 0.1 9.6 12.2 10.0 12.0 9.0 8.9 10.4 11.2 10.0 9.1 11.9 14.6 14.8 3.2 6.3 59.4 3.5 7.4 5.3 7.4 23.3 16.7 7.4 11.3 7.1 18.6 7.2 69.9 10.4 10.4 2.7 0.6 0.0 14.0 0.3 10.3 41.7 19.2 6.7 13.5 129.1 3.8 3.4 42.0 2.0 11.1 1.3 12.7 21.4 10.6 12.2 26.9 148.6 3.4 4.1 5.0 6.8 1.1 23.0 9.8 23.2 95.5 9.5 17.3 4.1 178.9 219.4 2.2 4.6 50.8 3.1 6.5 3.9 17.0 12.3 1.9 26.3 53.0 31.5 0.8 3.8 13.3 6.7 2.7 6.1 11.5 2.8 3.4 PKIG ENSG00000168734 "CAMP-dependent protein kinase inhibitor gamma" Q9Y2B9 20 44531785-44624247 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 233.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "memory B-cell: 370.6;naive B-cell: 377.4" "Lineage enriched" "Detected in all" 11 "B-cells: 377.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 540.5;HSkMC: 211.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042703, HPA063690" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA042703: AB_10797018, HPA063690: AB_2685091" "unprognostic (3.15e-2)" "unprognostic (5.65e-2)" "unprognostic (8.07e-2)" "unprognostic (1.44e-3)" "unprognostic (3.16e-1)" "unprognostic (9.49e-2)" "unprognostic (3.96e-2)" "unprognostic (6.46e-3)" "unprognostic (1.16e-1)" "unprognostic (1.38e-1)" "prognostic favorable (4.90e-5)" "unprognostic (6.26e-2)" "unprognostic (9.08e-2)" "unprognostic (1.19e-2)" "unprognostic (1.35e-2)" "unprognostic (4.22e-1)" "unprognostic (3.96e-2)" 90.3 76.6 77.4 59.0 80.0 20.7 74.2 70.9 95.6 105.2 78.0 189.1 30.3 111.4 37.8 76.4 101.7 73.8 289.9 82.7 82.5 104.5 44.5 162.9 49.4 80.9 77.0 57.5 32.3 66.8 69.1 82.3 72.5 102.4 31.5 26.9 45.9 75.3 104.8 31.4 72.2 92.6 73.1 42.7 81.8 68.3 83.4 19.3 68.4 91.1 46.7 169.0 68.9 73.4 27.8 27.9 44.7 28.8 67.0 135.7 6.2 66.0 540.5 73.6 55.4 64.7 12.5 108.3 52.7 58.5 61.2 10.6 9.0 14.4 23.9 54.8 16.3 16.7 4.1 45.7 61.7 2.1 1.1 211.7 28.5 35.8 7.9 36.4 167.5 29.3 13.4 2.6 6.8 35.0 17.2 27.5 23.7 0.2 39.4 2.8 1.2 2.6 40.7 5.5 18.0 58.7 16.9 7.9 45.6 19.3 21.0 13.6 108.5 99.9 44.2 44.8 32.3 13.9 41.9 76.3 49.5 1.9 43.8 2.9 1.8 0.7 1.5 1.7 1.3 370.6 1.9 1.8 9.1 377.4 5.4 8.8 2.2 4.4 1.6 35.8 1.0 17.8 77.4 80.0 70.9 95.6 82.7 82.5 80.9 77.0 72.5 73.1 83.4 73.4 93.3 9.6 6.1 26.8 82.9 25.2 14.4 20.3 10.2 24.6 37.6 45.1 233.6 24.3 15.7 46.0 20.9 15.1 6.2 44.2 127.2 70.6 110.1 104.2 91.5 122.3 44.2 34.9 65.9 30.8 17.8 93.2 5.1 18.5 47.5 27.8 65.0 37.8 8.2 10.1 42.7 15.7 32.6 3.8 20.4 40.1 73.0 14.2 49.8 22.5 8.1 94.1 3.1 25.6 25.4 39.1 46.9 61.3 11.8 11.6 19.3 156.6 78.3 28.7 118.3 19.5 153.0 155.9 27.4 5.3 30.0 36.7 8.5 80.8 29.1 10.2 PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 58.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 116.0;Horizontal cells: 38.7;Kupffer cells: 37.1;Syncytiotrophoblasts: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (3.47e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-3)" "unprognostic (6.84e-3)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.12e-3)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.84e-2)" "unprognostic (2.56e-1)" "unprognostic (9.29e-2)" "unprognostic (2.45e-3)" "unprognostic (2.98e-2)" "unprognostic (5.40e-3)" "unprognostic (6.28e-2)" "unprognostic (3.47e-2)" 15.1 11.5 12.9 7.6 12.5 7.0 9.8 12.8 18.1 6.6 9.2 8.0 6.9 6.2 8.7 6.2 7.4 9.3 35.5 13.1 14.2 33.4 17.3 17.5 13.6 13.1 14.1 7.7 7.4 11.4 11.4 27.3 14.6 8.1 5.9 4.4 9.1 5.7 58.3 13.9 6.5 8.8 12.4 20.3 8.4 10.8 15.9 11.7 13.2 22.4 5.1 8.8 6.4 16.1 10.0 10.0 7.9 25.5 36.7 26.8 19.0 24.6 31.6 35.7 30.2 26.1 18.6 17.4 31.2 34.1 28.5 15.2 8.5 10.4 15.9 6.0 16.4 5.0 10.4 19.0 19.6 4.6 25.0 19.0 11.2 35.2 5.5 44.6 22.5 8.9 7.9 9.8 23.0 21.3 7.2 14.5 5.1 9.4 12.1 9.9 11.3 55.3 17.7 8.7 3.0 5.1 31.2 9.6 19.2 6.6 25.2 23.7 18.8 31.5 15.0 41.1 16.5 34.6 33.5 22.1 28.6 13.8 12.0 19.6 24.1 16.0 4.7 27.5 4.8 5.0 5.2 7.0 14.1 5.3 6.5 5.5 1.0 2.3 32.4 12.2 5.1 14.6 12.9 12.5 12.8 18.1 13.1 14.2 13.1 14.1 14.6 12.4 15.9 16.1 4.4 6.4 3.3 3.6 3.0 4.8 2.4 6.8 2.8 12.1 7.0 6.0 22.5 1.5 5.1 9.2 8.4 20.9 4.9 8.1 5.9 10.1 1.9 4.3 4.8 5.9 0.0 1.7 7.0 7.2 7.6 8.2 8.6 9.0 15.2 6.6 9.3 13.7 116.0 38.7 6.7 8.5 2.0 37.1 6.8 6.1 2.1 21.4 12.4 10.3 7.7 4.4 3.1 5.5 3.9 6.3 5.0 1.5 2.6 2.6 3.0 19.5 2.7 6.1 0.0 5.5 6.7 3.4 2.8 4.1 3.4 50.8 3.9 3.1 4.1 2.0 PLAUR "CD87, UPAR, URKR" ENSG00000011422 "Plasminogen activator, urokinase receptor" Q03405 19 43646095-43670547 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "bone marrow: 688.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 820.7;Langerhans cells: 1833.9;Macrophages: 864.3;Urothelial cells: 2274.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1172.3" "Group enriched" "Detected in all" 4 "granulocytes: 1172.3;monocytes: 550.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 311.7;U-251 MG: 413.1;U-87 MG: 346.9;WM-115: 346.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050843, CAB073533" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA 4100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB073533: , HPA050843: AB_2681255" "unprognostic (9.28e-2)" "unprognostic (9.65e-3)" "unprognostic (1.39e-1)" "unprognostic (1.29e-3)" "unprognostic (3.59e-3)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "prognostic unfavorable (2.33e-5)" "unprognostic (8.08e-3)" "unprognostic (4.30e-2)" "unprognostic (2.29e-3)" "unprognostic (5.30e-2)" "prognostic unfavorable (7.83e-9)" "unprognostic (4.99e-2)" "unprognostic (1.66e-1)" "unprognostic (5.45e-2)" "unprognostic (9.33e-2)" 52.1 10.4 7.5 81.7 9.8 688.4 14.5 11.2 32.4 30.9 10.3 26.7 10.0 30.2 4.8 11.6 22.8 78.1 23.0 8.1 10.4 18.2 19.8 69.5 10.6 12.2 9.8 14.9 13.6 5.4 9.1 35.9 13.3 11.5 20.1 2.8 21.7 5.8 3.6 7.8 10.6 26.2 9.7 20.4 28.4 3.1 24.8 10.2 9.5 4.7 8.6 109.7 15.8 13.8 83.9 31.0 26.1 1.9 23.4 83.3 16.2 180.7 189.6 114.6 141.4 2.4 95.1 2.4 43.0 116.9 66.8 35.2 7.0 46.4 127.9 5.3 5.3 15.8 44.7 3.9 30.6 18.8 195.2 87.4 9.0 311.7 46.5 160.6 129.0 19.1 16.4 2.2 107.7 6.1 21.0 55.3 8.7 156.1 64.7 24.0 17.4 5.6 35.9 3.8 1.3 22.2 82.0 17.4 25.0 12.6 3.2 59.4 129.7 230.0 121.1 109.8 413.1 3.0 9.0 0.6 346.9 36.0 346.5 87.7 476.5 745.5 6.8 427.9 8.3 2.7 8.9 5.7 213.6 1.4 3.2 4.0 1172.3 6.7 550.7 69.3 3.6 253.9 7.5 9.8 11.2 32.4 8.1 10.4 12.2 9.8 13.3 9.7 24.8 13.8 23.1 73.7 76.6 2.3 15.5 105.2 820.7 274.2 72.3 0.7 45.8 22.5 4.5 24.3 151.9 20.2 0.0 6.5 17.4 314.5 1.9 219.3 0.9 188.1 68.0 64.9 14.8 5.2 2.5 106.5 58.8 145.4 156.0 519.1 305.2 4.2 19.2 1.7 428.9 10.1 3.3 85.3 22.4 155.4 1833.9 2.0 6.8 864.3 72.9 5.6 52.1 1.2 4.1 1.5 0.9 558.8 435.5 4.1 14.5 479.4 12.7 2.7 52.7 0.7 6.6 38.5 90.0 1.2 4.7 202.6 63.1 13.1 33.2 3.1 29.3 2274.4 PLEKHG4 "ARHGEF44, DKFZP434I216, SCA4" ENSG00000196155 "Pleckstrin homology and RhoGEF domain containing G4" Q58EX7 16 67277510-67289499 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 42.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 13.6;Granulosa cells: 13.3;Spermatocytes: 33.2;Spermatogonia: 21.5;Theca cells: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 3.3" "Not detected" "Not detected" HPA055696 Approved "Cell Junctions" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Cell Junctions" "HPA055696: AB_2682889" "unprognostic (2.63e-1)" "unprognostic (1.98e-3)" "unprognostic (1.16e-1)" "unprognostic (9.90e-2)" "unprognostic (3.40e-1)" "unprognostic (6.34e-2)" "unprognostic (1.50e-1)" "unprognostic (7.88e-2)" "unprognostic (6.88e-2)" "unprognostic (4.06e-3)" "unprognostic (4.48e-2)" "unprognostic (7.92e-2)" "prognostic unfavorable (6.72e-9)" "unprognostic (1.85e-1)" "unprognostic (6.78e-2)" "unprognostic (9.35e-3)" "unprognostic (5.01e-2)" 7.9 4.6 1.8 3.2 2.6 1.5 9.5 2.6 1.9 6.2 1.3 4.5 4.1 6.0 1.2 4.8 4.0 4.3 1.4 1.8 2.2 3.2 0.4 4.5 4.4 2.8 2.7 17.4 5.8 1.8 3.3 5.1 2.7 2.9 3.0 1.7 6.1 1.7 1.7 9.0 4.4 2.9 2.4 8.4 2.7 42.3 2.6 4.2 4.3 1.9 3.0 3.2 5.7 3.8 6.1 11.4 0.7 6.7 5.7 53.7 8.7 13.9 18.6 13.8 22.7 32.9 5.4 17.1 39.5 13.0 4.7 0.2 8.4 0.8 9.9 3.0 4.5 33.8 30.8 8.2 17.5 20.3 26.2 40.5 6.6 46.3 0.5 11.6 27.5 54.6 27.6 0.4 0.2 4.7 26.0 6.8 5.1 5.0 12.0 0.1 0.1 17.6 6.5 1.4 3.6 20.4 46.9 3.6 19.7 2.1 2.6 14.4 41.9 6.7 24.0 48.8 0.4 39.3 43.0 16.3 27.8 0.6 8.4 0.0 0.0 0.0 0.2 0.2 0.4 0.1 0.2 0.3 0.1 0.0 0.5 0.3 0.0 0.1 0.1 1.1 0.4 0.3 1.8 2.6 2.6 1.9 1.8 2.2 2.8 2.7 2.7 2.4 2.6 3.8 2.7 3.2 2.6 1.0 0.7 2.8 0.6 0.9 3.4 0.8 9.5 13.6 4.2 1.5 3.3 1.8 0.0 0.4 3.1 1.5 0.0 0.9 1.4 0.6 4.1 1.9 1.2 0.8 0.6 0.4 0.4 6.6 1.1 0.6 3.8 13.3 1.4 0.1 0.8 0.0 0.9 2.7 0.0 1.0 0.5 2.7 6.2 0.9 0.0 3.7 0.2 3.2 1.0 0.0 3.6 1.1 2.5 1.5 0.6 1.2 1.2 0.1 1.0 6.5 6.6 4.0 2.4 33.2 21.5 2.0 1.3 0.3 2.7 17.6 4.1 0.5 PLOD1 "LH1, LLH, PLOD" ENSG00000083444 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" Q02809 1 11934205-11975538 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 236.8;Sertoli cells: 105.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049137, HPA055799" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles Nucleoplasm "HPA049137: AB_2680649, HPA055799: AB_2682924" "unprognostic (1.00e-1)" "unprognostic (2.69e-3)" "unprognostic (9.21e-3)" "unprognostic (5.43e-2)" "unprognostic (7.53e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (4.15e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.91e-12)" "unprognostic (2.79e-1)" "unprognostic (7.12e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.43e-4)" 58.1 34.6 46.3 35.2 51.2 16.1 41.2 48.6 56.6 65.4 46.4 47.3 37.7 65.0 30.5 21.3 51.1 42.0 71.2 44.5 47.4 45.5 78.1 44.4 15.4 49.6 50.8 54.4 39.0 36.9 29.6 83.8 52.4 34.7 23.2 10.6 75.9 40.6 40.5 27.2 35.6 78.4 44.8 31.5 35.5 11.6 52.2 7.9 34.9 41.6 12.9 42.4 36.0 53.1 112.5 91.4 51.3 239.7 343.4 190.6 39.0 330.4 436.1 170.4 287.1 105.2 71.5 63.1 339.5 367.3 125.9 93.4 75.6 115.6 115.6 66.2 78.3 34.0 136.6 137.3 212.5 21.9 162.7 234.0 59.7 206.2 81.9 573.3 305.0 14.8 97.6 30.9 180.2 71.1 5.7 58.6 22.9 115.4 131.6 25.8 100.0 141.0 98.7 24.3 19.2 77.7 137.3 97.4 164.8 80.4 48.3 55.9 298.7 190.1 141.6 236.3 161.9 71.4 123.7 38.7 425.1 75.5 316.8 0.0 40.3 2.0 17.3 34.4 3.1 1.7 3.0 8.4 32.7 3.4 1.2 6.4 35.5 5.4 32.3 4.9 2.0 22.6 46.3 51.2 48.6 56.6 44.5 47.4 49.6 50.8 52.4 44.8 52.2 53.1 19.4 0.0 7.9 9.4 3.7 7.0 8.0 22.8 8.0 5.7 17.9 17.5 18.3 8.6 8.6 11.0 2.1 39.7 8.7 14.8 3.9 30.3 1.0 11.0 62.2 33.9 8.4 3.0 4.2 9.8 236.8 47.5 17.3 24.8 0.0 20.4 36.8 37.1 46.3 6.7 5.8 12.5 4.1 26.5 8.3 2.4 44.4 16.3 10.6 15.9 17.9 7.9 15.5 3.0 9.8 22.4 15.4 24.5 19.4 8.0 41.5 16.7 4.5 3.1 105.2 77.2 47.3 0.5 3.3 7.4 5.1 33.7 5.5 37.1 16.6 3.9 PLOD2 LH2 ENSG00000152952 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" O00469 3 146069440-146163653 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 130.9;Basal respiratory cells: 115.1;Distal enterocytes: 143.7;Extravillous trophoblasts: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBF TERT88: 636.0;hTERT-RPE1: 723.8;U-87 MG: 566.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025898, HPA069126" Approved Uncertain Nucleoli,Cytosol "Intracellular and membrane" NA NA 21000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "CAB025898: , HPA069126: " "unprognostic (8.68e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (2.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (1.29e-3)" "prognostic unfavorable (7.64e-10)" "prognostic unfavorable (1.42e-4)" "unprognostic (2.97e-2)" "unprognostic (3.36e-2)" "unprognostic (6.27e-3)" "unprognostic (2.24e-1)" "prognostic unfavorable (4.99e-11)" "prognostic unfavorable (2.83e-4)" "unprognostic (6.07e-2)" "unprognostic (4.06e-2)" "unprognostic (4.41e-3)" 63.1 20.1 13.4 35.6 14.5 1.1 18.6 15.1 17.2 10.2 19.4 36.2 42.2 23.5 13.4 18.2 11.4 41.5 22.1 13.3 15.1 26.1 57.3 12.9 3.8 23.1 18.1 20.5 18.7 16.5 7.9 80.6 16.3 13.2 29.9 56.6 9.5 16.2 3.0 3.9 35.0 46.8 17.8 5.4 20.1 8.5 20.6 10.5 90.0 3.9 5.5 25.7 10.0 17.6 134.5 94.3 29.0 9.5 102.5 109.6 73.2 465.5 141.6 247.7 463.0 7.2 13.4 0.0 88.8 79.5 113.1 27.8 34.0 400.5 636.0 0.6 53.5 33.3 84.3 66.9 262.5 0.1 0.6 192.9 56.5 215.2 104.1 723.8 347.7 0.1 45.1 1.8 441.6 48.8 0.3 0.6 18.5 0.3 40.0 0.2 19.2 0.6 105.0 6.5 14.5 0.5 370.3 39.4 39.9 135.1 107.5 4.2 440.4 304.2 92.2 97.8 280.7 138.9 20.9 0.5 566.5 0.4 55.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 13.4 14.5 15.1 17.2 13.3 15.1 23.1 18.1 16.3 17.8 20.6 17.6 29.1 16.0 11.4 130.9 0.4 7.0 6.4 115.1 30.1 17.1 23.7 10.2 14.3 44.3 47.0 27.6 35.5 9.2 0.3 143.7 9.8 64.5 0.5 35.4 13.8 24.3 19.8 4.6 22.8 53.1 130.6 68.1 19.9 38.7 0.0 42.7 21.0 65.2 5.1 0.0 46.4 19.5 22.4 1.0 2.5 1.2 13.1 3.0 14.2 21.5 0.7 53.8 0.0 64.3 6.0 82.4 48.8 4.9 1.3 8.9 50.5 8.2 33.0 24.7 19.7 36.9 47.2 11.0 18.0 27.5 5.5 18.7 1.0 24.5 25.1 5.6 PLPPR4 "KIAA0455, LPPR4, PHP1, PRG-1" ENSG00000117600 "Phospholipid phosphatase related 4" Q7Z2D5 1 99263953-99309590 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 23.5" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 10.9;Horizontal cells: 30.3;Muller glia cells: 21.4;Smooth muscle cells: 7.0" "Group enriched" "Detected in many" 4 "glioma: 7.2;melanoma: 2.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 14.1;BJ hTERT+ SV40 Large T+ RasG12V: 6.3;fHDF/TERT166: 6.0;SH-SY5Y: 11.4;U-138 MG: 6.7;U-87 MG: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (4.32e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-2)" "unprognostic (1.67e-2)" "unprognostic (2.95e-2)" "unprognostic (1.00e-2)" "unprognostic (1.17e-2)" "unprognostic (9.09e-2)" "unprognostic (9.70e-3)" "unprognostic (3.36e-2)" "unprognostic (2.21e-1)" "unprognostic (7.25e-12)" "unprognostic (1.67e-5)" "unprognostic (3.47e-1)" "unprognostic (1.34e-2)" "unprognostic (1.16e-3)" 1.5 0.5 8.4 0.2 13.1 0.0 0.7 0.0 16.6 1.8 0.0 0.3 0.3 0.4 0.3 1.5 0.3 3.0 0.3 23.5 2.1 0.3 0.0 1.4 0.4 0.0 0.1 0.0 0.5 0.3 2.1 0.8 0.0 0.1 0.3 3.8 0.3 0.2 0.1 1.7 0.5 0.7 0.0 0.3 0.3 2.9 5.5 0.3 0.6 0.2 0.6 3.4 0.3 1.4 0.0 0.0 0.0 2.3 0.2 0.0 0.0 3.2 14.1 3.6 6.3 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.1 0.0 0.1 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.4 13.1 0.0 16.6 23.5 2.1 0.0 0.1 0.0 0.0 5.5 1.4 4.3 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 4.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.4 10.9 2.5 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 30.3 0.0 0.0 0.0 0.0 0.0 0.4 5.3 0.2 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 1.3 0.7 4.5 0.0 0.0 7.0 1.2 0.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 PLS3 T-plastin ENSG00000102024 "Plastin 3" P13797 X 115561174-115650861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 209.3;Alveolar cells type 1: 211.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "NK-cell: 3.7;plasmacytoid DC: 12.2" "Group enriched" "Detected in many" 6 "dendritic cells: 12.2;NK-cells: 3.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020433, HPA076083" Approved Approved "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA020433: AB_2670440, HPA076083: AB_2686773" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "unprognostic (6.10e-2)" "unprognostic (4.37e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (6.07e-5)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (5.15e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.72e-4)" "prognostic unfavorable (7.04e-4)" 120.8 32.4 33.2 36.3 40.6 1.4 71.4 44.3 43.6 83.7 22.1 46.4 21.8 120.5 76.2 117.8 68.3 83.1 57.9 30.7 34.9 113.2 202.0 139.8 24.2 43.5 40.1 101.5 31.4 12.7 11.7 78.4 42.2 43.6 31.8 11.9 46.8 103.2 31.4 119.5 25.0 119.4 38.4 99.8 37.7 22.3 39.5 27.2 175.0 48.8 41.9 75.4 88.5 47.9 206.2 207.1 176.8 51.5 174.3 161.7 269.3 208.2 233.1 194.5 233.9 225.0 167.2 0.8 590.0 171.9 140.6 256.7 190.5 339.1 314.2 2.9 235.8 19.4 234.6 95.0 157.5 0.1 9.6 103.1 159.5 302.7 211.1 315.3 429.5 16.8 0.5 0.3 188.9 59.7 0.4 2.3 234.6 88.0 243.2 0.4 117.8 4.9 233.1 109.1 0.6 36.9 436.8 107.9 89.7 253.7 60.2 3.0 474.3 314.5 53.9 324.6 422.8 7.8 30.5 4.2 137.6 0.8 133.4 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.1 0.4 0.0 0.1 0.0 0.1 3.7 0.0 12.2 1.4 0.2 33.2 40.6 44.3 43.6 30.7 34.9 43.5 40.1 42.2 38.4 39.5 47.9 209.3 211.5 88.6 26.8 2.0 124.9 121.4 79.6 48.9 0.2 5.6 25.4 17.9 24.3 79.4 99.3 0.0 4.0 1.6 3.5 13.7 59.0 8.4 33.0 39.4 130.5 13.2 4.4 12.3 53.8 105.3 74.3 31.1 64.1 0.0 60.5 64.2 92.1 3.9 0.0 47.6 6.9 38.7 5.0 21.7 8.0 51.9 3.0 56.9 40.3 0.6 26.4 0.0 1.5 97.9 68.6 6.5 82.8 1.6 80.7 2.2 22.0 31.2 1.5 52.6 19.8 132.3 1.2 17.7 65.5 134.1 4.5 3.6 131.1 11.1 100.6 PMAIP1 "APR, NOXA" ENSG00000141682 "Phorbol-12-myristate-13-acetate-induced protein 1" Q13794 18 59899996-59904305 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 803.1;Endometrial ciliated cells: 463.6;Glandular and luminal cells: 529.8;Squamous epithelial cells: 474.5;Suprabasal keratinocytes: 691.2;Urothelial cells: 569.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 169.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 169.8" "Cell line enhanced" "Detected in many" "GAMG: 207.5;U-138 MG: 202.1" HPA051063 Uncertain Uncertain Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "HPA051063: AB_2681330" "unprognostic (1.35e-3)" "unprognostic (5.02e-2)" "unprognostic (5.57e-2)" "unprognostic (4.88e-2)" "unprognostic (6.65e-3)" "unprognostic (3.76e-2)" "unprognostic (2.00e-3)" "unprognostic (1.26e-2)" "unprognostic (4.41e-2)" "unprognostic (6.12e-2)" "unprognostic (8.47e-3)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.53e-1)" "unprognostic (7.68e-2)" "unprognostic (8.74e-2)" "unprognostic (1.09e-1)" 2.0 0.7 2.8 8.0 2.7 88.1 3.9 2.6 5.1 6.5 3.0 2.5 3.7 5.4 0.2 13.7 2.9 8.0 0.9 2.6 2.8 2.3 2.1 3.8 14.7 2.8 2.7 0.7 1.2 14.8 16.7 13.4 3.0 3.6 3.4 2.0 3.6 1.3 1.5 24.1 3.9 1.9 2.7 4.6 2.5 3.1 3.7 12.1 2.1 1.5 14.2 17.3 7.9 2.4 26.6 17.4 5.2 1.6 8.8 69.0 19.8 125.4 84.1 71.5 70.7 1.7 32.5 104.6 17.0 23.5 207.5 38.4 21.0 11.8 70.4 33.7 154.5 19.4 26.0 4.6 87.6 67.1 28.2 28.7 30.8 93.8 48.5 26.1 24.0 46.7 26.7 17.5 24.1 2.6 53.8 20.1 151.7 2.7 32.7 54.1 28.8 39.1 41.9 24.2 39.7 32.7 6.1 3.2 71.5 56.1 5.3 54.6 90.6 202.1 54.0 10.3 141.4 2.8 0.3 92.1 16.8 37.6 48.5 169.8 16.7 103.6 10.9 26.2 9.6 33.8 5.0 6.8 12.1 25.0 4.1 5.9 53.5 6.3 32.1 10.2 25.2 15.1 2.8 2.7 2.6 5.1 2.6 2.8 2.8 2.7 3.0 2.7 3.7 2.4 29.2 32.1 25.7 0.7 175.3 803.1 316.2 236.4 415.4 0.2 111.8 82.0 4.7 12.8 129.6 3.7 2.1 120.3 125.3 141.1 0.0 54.7 0.8 463.6 48.8 48.5 133.4 5.5 0.0 67.0 14.7 32.9 168.2 529.8 31.8 11.8 7.9 0.5 89.5 0.0 0.0 146.8 181.0 37.2 363.3 1.1 0.9 140.6 74.7 7.5 142.4 0.3 34.0 0.0 0.2 100.1 123.6 1.2 63.1 265.7 94.7 0.5 101.5 0.7 0.0 10.8 32.0 0.3 19.8 474.5 691.2 315.2 117.0 19.8 122.2 569.2 PMM1 Sec53 ENSG00000100417 "Phosphomannomutase 1" Q92871 22 41576900-41589871 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030712, HPA074950" Uncertain Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA030712: AB_10669600, HPA074950: " "unprognostic (2.66e-1)" "prognostic favorable (5.92e-4)" "unprognostic (3.25e-2)" "prognostic favorable (6.09e-6)" "unprognostic (1.25e-1)" "unprognostic (2.85e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "unprognostic (1.78e-1)" "prognostic favorable (2.05e-4)" "unprognostic (6.56e-3)" "unprognostic (5.76e-3)" "unprognostic (2.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "unprognostic (2.70e-1)" 47.0 51.7 49.0 12.0 50.4 26.2 39.0 47.0 65.0 34.4 41.2 33.6 37.7 26.9 19.2 73.7 34.7 18.8 26.5 49.5 52.1 59.4 64.2 33.8 17.5 46.9 47.2 48.1 45.0 15.4 19.5 14.2 51.2 26.5 20.3 13.6 23.3 20.2 16.2 33.2 33.8 19.9 47.8 13.7 65.7 32.6 49.8 14.3 13.8 11.4 16.8 31.7 28.0 49.7 16.0 29.0 19.6 42.5 54.3 84.0 23.0 61.7 69.8 56.0 61.0 23.0 15.3 14.9 20.3 74.4 40.0 23.4 25.8 40.0 31.1 31.2 38.6 3.8 34.8 49.2 85.8 22.6 23.8 70.4 38.2 58.3 24.2 61.9 9.3 23.8 16.9 51.9 76.5 42.0 17.1 32.5 6.2 75.1 38.2 13.1 20.7 30.7 24.0 17.1 5.8 11.2 50.5 18.1 75.2 15.2 20.3 24.4 7.5 63.2 34.3 59.4 32.8 33.2 34.0 24.3 70.3 18.8 38.7 21.0 22.0 44.8 27.7 18.5 22.3 17.8 27.6 22.8 23.2 20.5 29.4 21.1 28.8 13.4 22.9 9.2 49.4 18.8 49.0 50.4 47.0 65.0 49.5 52.1 46.9 47.2 51.2 47.8 49.8 49.7 7.8 35.3 106.4 16.3 15.0 14.8 10.2 22.5 20.5 16.7 22.8 29.3 12.4 82.9 25.8 35.0 6.2 57.1 10.0 104.8 107.6 31.8 17.1 77.7 34.2 6.9 48.7 19.3 14.9 11.0 91.1 33.3 36.2 51.4 3.8 60.9 8.9 83.5 34.5 28.6 10.9 58.1 14.2 14.4 13.5 15.3 28.0 16.3 44.4 3.7 21.9 67.1 16.5 4.0 7.1 10.8 117.0 30.5 17.7 8.5 176.1 138.5 34.8 22.6 39.5 18.9 36.9 72.6 10.9 23.1 14.1 65.3 21.0 37.9 55.3 8.2 POFUT2 "C21orf80, FUT13, KIAA0958" ENSG00000186866 "Protein O-fucosyltransferase 2" Q9Y2G5 21 45263928-45287898 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 95.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044297 Uncertain "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA044297: AB_10965176" "unprognostic (1.32e-2)" "unprognostic (1.65e-3)" "prognostic unfavorable (4.55e-7)" "unprognostic (1.49e-2)" "unprognostic (4.09e-3)" "unprognostic (5.03e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (2.62e-1)" "unprognostic (2.15e-1)" "unprognostic (4.16e-2)" "unprognostic (4.20e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.66e-12)" "unprognostic (1.56e-2)" "unprognostic (2.53e-1)" "unprognostic (3.91e-3)" "unprognostic (5.25e-2)" 15.7 20.7 9.4 8.5 9.6 14.0 14.1 9.5 10.9 20.2 21.2 17.3 9.7 16.1 8.9 8.6 20.4 10.3 16.6 9.6 13.8 19.6 20.5 16.1 7.7 11.9 12.1 27.7 19.0 8.2 31.4 16.8 11.8 19.1 6.3 8.6 14.5 10.3 7.8 8.6 15.0 12.0 9.6 16.9 15.3 17.6 13.7 5.3 22.2 5.1 6.5 15.9 13.9 9.6 10.4 11.2 22.1 24.5 39.3 36.1 10.3 57.1 45.4 25.9 38.7 24.0 17.2 7.2 41.9 95.1 58.5 10.4 13.1 22.9 27.9 12.1 15.2 14.4 17.4 18.8 45.4 10.7 18.4 25.6 14.7 32.4 17.7 84.5 25.6 9.5 13.5 11.6 27.4 10.7 5.3 17.7 27.6 17.3 15.7 10.8 6.6 9.1 14.4 9.4 9.6 14.0 33.6 20.3 21.1 24.6 14.8 15.4 28.5 19.5 19.0 30.2 25.8 27.7 15.4 5.5 39.9 13.2 30.8 0.3 0.3 0.8 0.3 0.3 0.5 0.2 0.3 0.2 0.1 0.2 0.4 0.4 0.5 0.3 0.3 0.4 0.3 0.3 9.4 9.6 9.5 10.9 9.6 13.8 11.9 12.1 11.8 9.6 13.7 9.6 12.4 6.4 9.6 19.6 10.7 6.6 7.0 6.8 6.2 6.9 11.8 9.5 8.7 11.5 7.0 12.9 10.4 9.0 14.7 7.4 3.9 7.6 34.9 29.4 17.5 8.7 10.1 7.4 6.8 6.2 13.5 19.8 13.3 15.9 7.0 20.4 10.0 8.6 6.9 5.0 9.9 14.7 4.1 4.8 8.8 51.2 14.6 8.1 8.8 7.5 8.0 10.2 3.1 11.1 7.6 8.0 7.5 13.9 12.4 7.3 6.6 3.9 30.6 14.5 0.0 14.5 17.5 20.1 5.2 4.5 4.0 13.5 12.3 12.2 7.8 7.9 POLK "DINB1, DINP, POLQ" ENSG00000122008 "DNA polymerase kappa" Q9UBT6 5 75511756-75601144 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 236.8;Oligodendrocytes: 159.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012035, HPA057303, HPA068117, HPA069375" Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA012035: AB_2668606, HPA057303: AB_2683406, HPA068117: AB_2685957, HPA069375: AB_2686131" "unprognostic (9.66e-2)" "unprognostic (5.29e-2)" "unprognostic (5.37e-2)" "unprognostic (2.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.66e-1)" "unprognostic (1.73e-2)" "unprognostic (7.76e-2)" "unprognostic (1.65e-2)" "unprognostic (6.29e-3)" "unprognostic (2.42e-1)" "unprognostic (5.93e-2)" "unprognostic (1.80e-2)" "unprognostic (9.96e-3)" "unprognostic (1.58e-1)" "unprognostic (9.64e-2)" "unprognostic (2.02e-1)" 4.7 4.3 2.3 3.7 5.0 2.7 5.4 7.0 4.5 6.8 1.9 3.2 2.4 6.3 4.6 3.4 4.0 3.7 4.6 3.1 5.4 4.7 4.9 4.9 4.0 5.6 4.2 6.0 4.3 5.5 3.2 6.3 5.7 4.3 3.1 5.2 4.2 3.9 4.6 4.1 3.1 4.1 3.6 5.6 3.7 3.1 4.7 3.9 7.6 3.3 3.6 3.2 3.9 10.5 6.7 6.7 4.1 5.3 5.3 10.5 3.5 12.5 8.8 9.5 9.8 4.3 5.2 6.9 10.0 8.3 6.2 2.5 3.8 4.3 11.4 7.6 4.5 6.3 5.7 2.1 10.1 4.0 4.9 5.0 5.1 7.7 5.3 7.6 8.0 4.4 5.6 3.9 9.1 0.5 7.9 3.2 1.5 0.7 3.9 3.3 10.6 4.8 5.7 2.2 4.1 4.6 9.4 2.5 3.4 2.8 3.7 3.8 10.4 6.9 3.6 3.3 7.2 4.5 4.4 6.0 4.6 6.2 12.2 5.8 5.3 2.7 2.4 6.0 2.0 5.1 2.6 3.0 4.8 4.1 3.2 2.2 4.6 3.9 11.5 5.8 3.4 2.0 2.3 5.0 7.0 4.5 3.1 5.4 5.6 4.2 5.7 3.6 4.7 10.5 45.8 32.1 44.6 65.6 36.3 14.7 21.8 22.1 20.5 32.9 19.5 15.0 21.8 24.3 26.1 29.5 20.9 17.3 37.5 8.3 23.5 20.3 236.8 19.5 32.1 34.4 14.9 29.2 63.5 15.8 13.0 33.7 17.3 21.0 51.9 33.8 57.1 25.0 21.8 65.6 60.0 11.3 24.4 39.2 25.0 58.7 37.6 33.3 23.2 73.1 55.8 19.6 25.7 84.4 159.6 19.1 15.1 38.4 26.4 14.6 17.8 21.2 20.8 38.8 6.6 38.5 27.8 61.3 23.6 14.5 12.9 6.7 27.6 48.8 12.2 11.6 POLR3H "C25, KIAA1665, RPC8" ENSG00000100413 "RNA polymerase III subunit H" Q9Y535 22 41525799-41544606 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 163.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046787 Approved Supported Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Centrosome" "HPA046787: AB_2679806" "unprognostic (1.55e-1)" "unprognostic (6.74e-2)" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (9.57e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.05e-2)" "unprognostic (1.33e-2)" "unprognostic (5.43e-2)" "prognostic favorable (5.41e-4)" "unprognostic (6.40e-2)" "unprognostic (1.54e-1)" "unprognostic (2.94e-2)" "unprognostic (1.49e-1)" "unprognostic (4.00e-2)" "unprognostic (1.70e-1)" 16.6 21.0 40.4 8.5 38.9 5.4 15.1 38.0 49.5 11.0 33.3 13.4 4.8 14.0 9.0 16.4 15.8 7.9 18.3 39.5 38.6 13.5 26.7 14.2 10.0 41.1 41.7 18.5 12.2 11.9 18.2 6.5 38.1 15.4 5.2 7.0 11.5 10.7 13.8 12.1 9.7 11.7 40.1 10.9 13.4 16.2 41.3 8.0 14.1 9.0 7.7 14.2 9.8 39.4 36.4 23.8 21.4 32.7 23.0 20.9 14.8 30.5 27.3 49.0 39.3 47.9 12.0 30.8 21.9 49.9 27.8 17.8 39.8 48.1 30.6 26.3 50.1 18.4 37.1 23.7 23.9 75.3 30.8 26.3 30.8 64.9 17.4 18.8 23.5 29.3 39.5 19.9 28.0 34.4 19.3 20.1 15.6 49.8 28.1 30.0 16.9 32.6 22.9 21.7 21.2 12.5 37.0 39.7 19.3 13.7 15.6 21.1 22.7 29.8 30.7 49.8 39.8 16.7 28.6 46.6 49.5 26.8 28.9 0.1 12.5 0.2 8.8 18.3 12.6 16.6 8.7 10.4 14.2 13.9 11.6 9.7 0.6 5.4 18.6 13.3 5.8 9.9 40.4 38.9 38.0 49.5 39.5 38.6 41.1 41.7 38.1 40.1 41.3 39.4 6.1 0.0 32.0 15.7 14.8 17.7 12.0 19.0 13.6 18.8 24.9 23.4 6.4 14.3 19.8 16.5 16.7 32.9 7.9 5.0 46.9 30.4 42.6 12.7 15.4 10.3 14.3 19.1 10.0 29.6 30.9 14.8 13.3 8.9 11.4 13.1 9.7 33.3 30.5 21.9 7.1 4.8 14.2 9.5 11.0 163.9 16.8 10.2 24.9 1.9 19.6 24.1 18.6 2.0 6.7 27.6 6.6 20.3 21.8 16.8 4.1 40.7 12.7 20.9 0.0 17.9 16.8 51.6 50.9 21.2 25.6 17.9 10.3 21.2 9.5 11.8 PPP1R12A "M130, MBS, MYPT1" ENSG00000058272 "Protein phosphatase 1 regulatory subunit 12A" O14974 12 79773563-79935460 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 353.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041296, HPA071956" Approved Supported "Actin filaments,Cytosol" NA NA 270000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments, Cytosol" "HPA041296: AB_2677394, HPA071956: AB_2732192" "unprognostic (3.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-1)" "unprognostic (5.60e-3)" "unprognostic (6.19e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (1.61e-1)" "unprognostic (9.69e-3)" "unprognostic (1.85e-1)" "unprognostic (2.04e-2)" "unprognostic (1.04e-1)" "unprognostic (2.44e-3)" "unprognostic (5.50e-2)" "unprognostic (1.95e-1)" "unprognostic (2.45e-1)" "unprognostic (1.38e-1)" 31.5 18.6 21.2 32.3 26.6 57.5 21.7 25.3 65.3 34.1 15.0 73.3 22.8 66.2 31.1 71.2 40.9 36.6 28.0 27.7 20.3 18.2 14.2 24.6 31.9 14.3 14.5 27.4 11.0 18.5 11.2 41.6 14.2 67.6 35.4 14.6 19.0 84.8 20.5 17.6 27.6 83.7 14.1 30.8 29.2 23.5 20.7 34.3 24.9 27.2 27.8 64.5 27.7 27.0 42.9 36.5 49.3 28.5 36.8 36.2 45.8 84.0 46.5 53.1 35.2 34.9 20.7 36.9 33.4 113.8 21.4 33.4 38.6 32.9 63.8 51.3 24.3 98.2 40.5 24.1 29.1 64.8 59.5 30.7 24.3 53.6 49.1 60.1 37.2 36.7 41.1 43.0 57.0 27.7 71.4 34.3 39.1 18.8 25.2 57.9 54.4 27.8 31.4 66.6 23.8 17.9 66.3 23.2 28.5 45.1 32.4 30.9 56.8 56.3 29.9 40.1 48.2 28.3 27.8 48.6 19.2 36.3 49.3 155.1 44.4 197.4 62.8 47.5 56.5 56.8 59.7 66.8 41.8 52.8 47.3 61.3 187.2 98.2 70.4 35.3 69.6 46.3 21.2 26.6 25.3 65.3 27.7 20.3 14.3 14.5 14.2 14.1 20.7 27.0 108.4 76.9 65.9 168.5 79.7 84.5 69.0 59.1 57.5 82.2 30.7 69.0 127.4 32.9 61.5 53.3 35.5 66.7 113.4 44.9 15.6 50.9 111.3 47.5 113.6 93.6 44.9 66.3 240.4 40.0 82.0 82.4 42.8 81.2 121.4 66.6 55.0 27.5 78.0 102.6 135.4 37.7 44.7 57.5 100.8 64.2 86.3 92.8 60.5 132.1 112.0 52.2 120.5 353.9 132.9 55.9 42.7 147.4 60.7 52.0 34.3 26.3 41.0 61.4 210.4 74.6 332.7 133.4 89.8 50.9 81.1 83.7 119.7 81.5 41.3 63.6 PPP1R3C "PPP1R5, PTG" ENSG00000119938 "Protein phosphatase 1 regulatory subunit 3C" Q9UQK1 10 91628442-91633071 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 908.0;tongue: 448.5" "Group enriched" "Detected in many" 8 "Astrocytes: 201.8;Cardiomyocytes: 232.0;Hepatocytes: 64.2;Muller glia cells: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 41.9;HHSteC: 51.7;hTERT-RPE1: 85.4;LHCN-M2: 102.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027041 Uncertain NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027041: AB_1855649" "unprognostic (2.11e-1)" "unprognostic (1.86e-3)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.15e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-2)" "unprognostic (6.38e-2)" "unprognostic (1.85e-2)" "unprognostic (1.75e-3)" "unprognostic (5.63e-3)" "unprognostic (1.59e-2)" "unprognostic (5.48e-3)" "unprognostic (8.44e-3)" "unprognostic (4.86e-2)" "unprognostic (2.49e-1)" "unprognostic (4.61e-3)" 14.1 12.2 39.3 3.4 51.5 0.0 9.9 39.8 44.6 97.1 21.4 16.2 4.0 10.3 12.0 106.8 10.2 14.4 170.5 40.1 42.9 11.6 164.2 12.3 1.4 44.1 55.1 10.2 18.7 4.5 5.7 15.6 43.9 29.1 4.1 83.2 28.4 35.7 908.0 17.0 5.8 15.4 39.6 3.0 17.5 2.5 42.4 0.5 2.7 448.5 6.2 19.8 136.7 38.0 0.0 6.6 1.8 26.8 11.9 5.6 0.0 29.8 23.2 12.0 12.8 0.0 2.2 0.0 1.2 28.0 4.8 1.6 0.7 3.2 22.0 0.0 0.1 0.4 41.9 4.8 51.7 0.0 0.0 19.1 5.2 7.6 0.4 85.4 3.0 0.0 14.4 0.0 102.5 1.0 0.0 0.0 1.7 0.0 0.0 0.0 6.4 0.0 1.1 26.2 0.9 1.8 0.0 0.0 0.0 0.0 0.2 4.5 20.3 5.3 5.2 7.0 4.3 0.2 0.6 0.0 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.3 51.5 39.8 44.6 40.1 42.9 44.1 55.1 43.9 39.6 42.4 38.0 2.4 0.0 0.0 201.8 0.4 4.6 9.3 0.8 0.6 9.7 4.8 2.5 232.0 1.5 0.2 3.7 0.0 0.2 0.0 0.3 7.9 3.1 0.1 0.3 0.7 3.5 10.1 0.0 1.7 11.4 0.5 11.9 0.0 0.6 0.0 0.4 2.5 64.2 1.4 18.5 3.0 0.5 2.0 1.6 1.5 0.1 2.8 0.6 12.4 5.6 0.0 133.1 0.0 3.5 0.5 4.0 0.1 7.5 0.0 2.5 0.0 1.8 0.4 12.8 0.0 9.4 18.6 0.7 1.7 5.4 4.0 0.3 0.7 0.1 0.1 0.7 PPP2R3A "PPP2R3, PR130, PR72" ENSG00000073711 "Protein phosphatase 2 regulatory subunit B''alpha" Q06190 3 135965728-136147894 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 51.2;skeletal muscle: 180.5;tongue: 117.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.3;Oligodendrocytes: 201.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 37.4;BJ hTERT+: 35.3;RPTEC TERT1: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035829, HPA035830, HPA065338" Uncertain Approved "Golgi apparatus" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" "HPA035829: AB_10696513, HPA035830: AB_10670121, HPA065338: AB_2685475" "unprognostic (3.35e-1)" "unprognostic (2.37e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.71e-1)" "unprognostic (4.04e-1)" "unprognostic (1.44e-4)" "unprognostic (9.43e-2)" "unprognostic (1.27e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (8.92e-2)" "prognostic favorable (1.15e-5)" "unprognostic (4.55e-2)" "unprognostic (3.06e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (3.91e-4)" 3.1 3.4 3.3 2.3 7.2 0.2 7.1 4.3 5.0 5.2 3.9 8.0 2.0 7.7 5.1 8.3 4.1 5.0 51.2 4.2 4.9 22.0 1.1 3.9 0.6 5.7 5.5 5.6 3.4 11.7 1.8 2.8 5.3 5.9 5.4 2.6 8.9 6.5 180.5 18.9 2.3 9.6 4.3 1.1 7.4 7.2 6.0 0.6 3.1 117.6 1.2 4.5 4.0 13.7 37.4 2.0 10.3 5.0 8.1 10.2 11.9 28.5 35.3 13.2 16.3 2.4 2.4 0.1 10.7 29.3 9.5 4.7 4.3 10.0 28.3 0.1 1.4 1.6 1.0 0.1 5.8 0.0 1.4 9.3 8.5 16.8 7.8 13.3 12.8 1.0 1.0 0.1 19.2 6.2 0.3 0.2 7.2 0.4 6.9 0.1 15.1 0.1 46.2 1.4 0.7 5.7 4.7 5.7 10.9 9.2 9.1 0.5 8.4 13.7 7.5 18.8 12.7 0.4 1.0 0.1 10.1 0.8 4.9 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 3.3 7.2 4.3 5.0 4.2 4.9 5.7 5.5 5.3 4.3 6.0 13.7 7.9 28.9 27.6 51.6 2.8 26.4 19.5 7.1 19.4 5.7 19.9 15.5 115.3 8.6 10.0 55.2 0.0 10.9 6.7 25.3 21.5 20.6 8.4 9.9 19.0 11.4 13.1 0.4 35.2 9.9 15.4 14.8 21.9 16.1 3.8 15.7 8.6 2.9 2.5 3.3 47.2 6.9 6.1 2.4 9.8 10.7 24.5 3.2 28.4 13.1 9.6 8.9 2.1 72.4 201.1 17.2 10.6 18.4 1.5 17.8 21.7 40.1 8.1 2.6 6.6 29.0 14.0 10.1 18.6 15.3 33.2 10.4 3.4 6.7 8.9 15.6 PRKG1 "PGK, PKG, PKG1, PRKG1B, PRKGR1B" ENSG00000185532 "Protein kinase cGMP-dependent 1" Q13976 10 50990888-52298423 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 36.1" "Cell type enhanced" "Detected in many" "Astrocytes: 778.3;Excitatory neurons: 244.9;Inhibitory neurons: 473.0;Microglial cells: 188.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 36 "basophil: 7.3" "Lineage enriched" "Detected in single" 49 "granulocytes: 7.3" "Cell line enhanced" "Detected in many" "AN3-CA: 14.3;BJ hTERT+: 19.2;fHDF/TERT166: 16.1;U-138 MG: 11.2;U-87 MG: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007699, CAB009629" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "CAB009629: AB_2170663, HPA007699: AB_1079677" "unprognostic (3.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.44e-2)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (5.54e-1)" "unprognostic (2.23e-1)" "unprognostic (4.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (9.26e-2)" "unprognostic (5.50e-3)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (3.78e-4)" 7.0 8.3 6.4 2.7 7.2 0.6 3.1 1.4 6.9 10.3 12.4 5.5 2.4 10.3 3.5 5.2 5.2 7.0 14.1 6.6 10.7 3.8 1.7 6.8 1.2 5.1 4.6 4.2 1.7 9.6 1.3 10.1 3.2 6.4 5.3 3.6 4.0 8.1 25.8 1.0 3.4 14.6 5.3 2.5 3.3 1.8 12.2 1.5 7.0 36.1 0.9 5.4 4.2 2.7 0.1 0.2 1.7 14.3 6.5 6.0 0.1 5.4 19.2 2.1 2.6 0.1 0.9 0.3 0.0 16.1 2.0 0.1 0.0 0.1 1.7 0.0 5.0 1.0 0.3 0.0 5.5 0.0 0.1 8.1 0.1 4.8 0.1 0.6 0.0 0.0 0.0 0.1 5.3 0.1 0.0 0.0 4.1 0.0 2.5 0.0 3.9 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 2.0 0.1 0.0 0.0 11.2 1.9 5.9 3.7 1.5 0.8 0.0 10.0 0.0 2.5 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 6.4 7.2 1.4 6.9 6.6 10.7 5.1 4.6 3.2 5.3 12.2 2.7 10.5 16.0 10.8 778.3 0.3 0.9 1.7 0.0 7.4 5.9 2.8 9.4 31.4 0.0 0.0 3.7 0.0 1.0 0.3 2.9 0.0 2.4 56.0 0.4 14.7 7.1 0.0 3.4 244.9 3.6 1.2 24.2 0.5 0.5 4.5 0.1 5.0 0.0 0.4 0.0 473.0 4.2 0.0 0.0 2.2 53.0 32.6 5.3 3.6 188.3 0.0 23.6 0.0 24.6 8.0 4.8 14.1 39.5 0.1 0.5 3.2 0.2 0.9 1.3 39.5 3.9 69.9 0.9 0.9 1.6 0.6 2.2 0.2 7.9 3.6 1.0 PRR16 DSC54 ENSG00000184838 "Proline rich 16" Q569H4 5 120464300-120687332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 30.4" "Group enriched" "Detected in many" 9 "Excitatory neurons: 171.6;Inhibitory neurons: 188.9" "Cancer enriched" "Detected in many" 5 "prostate cancer: 13.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 77.3;BJ hTERT+: 83.9;fHDF/TERT166: 102.1;HSkMC: 62.5;hTERT-RPE1: 103.0;LHCN-M2: 97.9;U-138 MG: 117.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049254 Approved Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Midbody, Cytosol" "HPA049254: AB_2680693" "unprognostic (1.71e-1)" "unprognostic (3.87e-2)" "unprognostic (3.45e-1)" "unprognostic (1.20e-1)" "unprognostic (6.61e-2)" "unprognostic (7.07e-2)" "unprognostic (1.53e-1)" "unprognostic (2.42e-2)" "unprognostic (8.33e-2)" "unprognostic (4.40e-2)" "unprognostic (2.76e-2)" "unprognostic (2.06e-1)" "unprognostic (2.54e-8)" "unprognostic (3.05e-2)" "unprognostic (9.13e-2)" "unprognostic (2.65e-1)" "unprognostic (2.38e-3)" 11.0 2.8 2.0 5.2 2.1 0.2 7.9 6.1 3.5 14.9 0.0 5.1 1.7 11.8 1.5 1.8 7.0 5.7 12.7 2.2 5.1 3.0 0.9 9.8 1.1 3.4 1.8 5.6 2.0 1.1 1.7 9.7 3.2 9.3 4.5 7.0 2.6 2.4 26.4 4.0 5.0 8.2 0.7 2.5 4.0 2.4 2.3 0.7 4.4 30.4 0.9 9.5 10.0 1.4 3.7 0.0 8.0 0.0 22.2 77.3 0.0 37.0 83.9 51.5 39.1 0.0 0.2 0.0 0.0 102.1 9.3 0.0 8.1 0.9 53.8 0.0 1.9 0.0 1.2 0.0 21.5 0.2 0.1 62.5 8.9 15.4 48.0 103.0 1.7 0.0 0.1 0.1 97.9 0.0 0.0 0.0 0.9 0.0 1.4 0.0 6.2 0.0 4.3 0.0 0.3 16.1 0.1 0.0 1.1 6.1 0.1 0.1 0.5 117.9 13.3 3.8 19.4 0.3 0.0 0.0 6.7 0.2 4.1 0.1 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.3 2.0 2.1 6.1 3.5 2.2 5.1 3.4 1.8 3.2 0.7 2.3 1.4 1.4 0.0 0.0 14.0 0.4 1.3 6.2 0.0 0.0 7.5 1.5 1.9 3.2 0.0 0.0 0.0 14.6 0.1 0.1 0.0 0.0 0.1 16.8 0.9 18.9 0.8 0.0 0.0 171.6 0.0 0.0 13.5 0.0 0.8 0.0 0.2 0.4 0.0 0.5 15.2 188.9 0.0 0.0 1.8 2.7 11.6 2.8 1.0 1.8 9.4 0.1 2.6 0.0 7.5 3.9 0.2 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.7 0.0 1.4 9.6 0.9 1.4 0.5 0.6 0.5 0.4 3.1 0.0 0.7 PRRC1 FLJ32875 ENSG00000164244 "Proline rich coiled-coil 1" Q96M27 5 127517640-127555085 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039212 Supported Approved Vesicles NA NA 170000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA039212: AB_10794634" "prognostic unfavorable (9.35e-5)" "unprognostic (9.01e-2)" "unprognostic (5.26e-3)" "unprognostic (6.36e-2)" "unprognostic (2.95e-1)" "unprognostic (4.47e-2)" "unprognostic (4.21e-2)" "unprognostic (1.39e-1)" "unprognostic (6.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.74e-3)" "unprognostic (5.53e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-1)" "unprognostic (2.83e-1)" "unprognostic (3.45e-3)" "unprognostic (2.19e-1)" 17.3 18.7 7.0 18.1 8.1 21.2 24.2 8.3 9.3 27.5 12.4 23.5 25.3 22.0 23.4 20.2 15.9 17.1 14.5 6.5 7.6 21.4 26.7 18.2 17.9 7.9 8.0 22.3 32.1 30.4 19.1 27.0 8.6 21.1 27.2 11.5 25.6 18.0 12.9 19.2 24.4 22.4 7.8 16.2 24.0 13.2 7.5 19.5 26.6 10.2 20.9 19.4 17.3 9.9 30.3 30.5 44.5 34.0 58.8 75.1 51.9 52.3 58.4 45.7 71.8 52.4 34.6 33.6 53.2 83.6 34.4 26.9 35.0 64.8 70.6 46.7 24.4 29.3 29.1 45.6 33.8 27.4 36.9 51.5 46.7 48.5 56.3 41.9 49.4 31.6 25.5 40.2 53.4 34.2 53.9 29.4 25.5 43.5 39.5 20.5 58.9 43.8 36.4 37.6 32.4 25.0 41.0 44.1 40.1 40.6 47.2 35.3 58.9 41.8 31.2 49.3 37.2 33.5 26.8 43.6 49.3 42.9 42.0 18.7 11.7 9.4 18.6 13.5 22.6 15.4 15.1 16.0 15.6 11.2 16.5 14.9 3.6 12.7 13.5 10.4 13.0 12.3 7.0 8.1 8.3 9.3 6.5 7.6 7.9 8.0 8.6 7.8 7.5 9.9 16.3 35.3 25.5 9.8 17.8 14.7 14.0 37.2 22.8 12.8 24.1 15.0 12.5 27.1 40.6 27.6 14.6 25.5 14.0 38.2 13.7 30.5 3.8 16.2 33.6 22.8 15.6 12.4 13.5 30.9 42.2 30.8 28.5 23.2 15.8 28.7 26.0 37.3 21.7 8.4 13.5 50.2 28.5 20.2 7.6 4.8 34.5 14.7 19.6 15.9 17.8 10.7 22.6 18.6 25.1 31.8 25.1 30.1 38.0 26.6 34.1 28.0 30.0 12.7 13.1 18.8 26.4 13.6 21.2 18.2 18.6 31.6 19.3 21.7 33.6 26.0 PRRX2 "PMX2, PRX2" ENSG00000167157 "Paired related homeobox 2" Q99811 9 129665647-129722674 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.3;skin 1: 25.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 27.4;Early spermatids: 78.7;Fibroblasts: 44.2;Langerhans cells: 28.0;Smooth muscle cells: 21.2;Suprabasal keratinocytes: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 12.9;BJ: 28.7;BJ hTERT+: 20.3;fHDF/TERT166: 41.6;U-2197: 34.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 1.3" "HPA006607, HPA026808" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA006607: AB_2667623, HPA026808: AB_10603228" "unprognostic (4.02e-2)" "unprognostic (5.17e-2)" "unprognostic (7.65e-3)" "unprognostic (4.47e-3)" "unprognostic (2.77e-1)" "unprognostic (1.92e-1)" "unprognostic (2.16e-2)" "unprognostic (1.03e-2)" "unprognostic (8.58e-3)" "unprognostic (9.27e-2)" "unprognostic (1.22e-1)" "unprognostic (1.22e-1)" "unprognostic (1.94e-10)" "unprognostic (6.66e-2)" "unprognostic (4.48e-1)" "unprognostic (2.65e-2)" "unprognostic (9.47e-3)" 14.2 2.4 0.5 1.2 0.5 0.0 11.7 0.4 0.7 23.3 1.0 2.2 0.2 3.9 0.2 5.4 3.4 1.3 9.5 0.6 1.2 1.2 0.1 4.6 1.1 0.5 0.5 1.3 0.9 0.5 4.5 1.4 0.6 14.1 0.3 0.0 7.5 2.7 1.6 25.5 1.6 0.6 0.4 0.1 2.8 10.7 0.5 0.3 9.5 0.6 0.8 10.7 18.3 0.5 0.0 0.7 0.0 1.1 3.3 12.9 0.1 28.7 20.3 3.6 4.0 0.0 0.0 0.0 10.2 41.6 1.5 0.3 0.8 0.0 0.3 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.1 1.1 0.0 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.6 0.0 0.0 4.4 2.1 6.4 0.0 0.0 0.0 0.9 0.0 0.0 2.7 1.3 0.1 0.0 1.4 2.7 0.5 0.0 0.0 8.3 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.4 0.7 0.6 1.2 0.5 0.5 0.6 0.4 0.5 0.5 3.9 0.0 0.0 0.7 0.1 27.4 1.1 16.0 0.6 0.0 6.0 6.0 0.3 0.0 10.1 0.0 0.0 0.2 0.1 0.0 1.9 0.1 78.7 1.0 6.3 3.0 0.0 0.0 0.4 0.0 0.4 44.2 0.5 1.8 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 2.0 0.0 28.0 10.2 2.8 0.3 8.8 0.0 0.0 0.0 0.0 5.0 0.1 0.9 0.0 3.4 0.0 4.0 0.0 0.1 7.9 0.0 0.0 0.4 21.2 3.6 6.8 0.5 29.7 0.4 0.8 0.0 0.0 6.2 PSG4 ENSG00000243137 "Pregnancy specific beta-1-glycoprotein 4" Q00888 19 43192702-43207299 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "parathyroid gland: 55.6;placenta: 143.4" "Cell type enriched" "Detected in some" 38 "Syncytiotrophoblasts: 553.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "fHDF/TERT166: 552.6;U-2197: 147.3" HPA046327 Supported "Secreted in female reproductive system" NA NA 58000000 "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (4.29e-2)" "unprognostic (5.18e-2)" "unprognostic (9.49e-2)" "unprognostic (2.52e-2)" "unprognostic (3.63e-2)" "unprognostic (1.94e-1)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (7.75e-2)" "unprognostic (8.82e-3)" "unprognostic (1.03e-3)" "unprognostic (1.68e-2)" "unprognostic (2.85e-1)" "unprognostic (2.57e-1)" 0.1 0.1 0.1 0.0 0.1 0.0 1.1 0.9 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.5 55.6 0.1 143.4 0.0 0.2 0.0 0.0 1.2 0.2 0.0 3.3 0.0 1.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.8 0.0 1.8 0.1 0.7 0.3 0.0 2.7 0.0 1.9 552.6 4.6 0.0 0.2 0.4 5.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 8.2 53.6 3.6 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.4 0.0 0.0 0.0 7.1 0.9 14.5 0.0 0.0 4.4 2.1 5.5 147.3 0.1 0.2 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.3 0.0 1.5 0.4 0.5 0.3 0.0 0.3 0.0 0.0 4.7 0.0 0.0 0.0 14.3 0.1 0.1 0.2 0.1 0.0 0.0 1.0 0.0 11.9 0.4 0.0 2.7 0.0 0.1 0.0 0.0 2.0 0.0 1.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.5 0.3 0.7 0.0 0.0 0.0 2.7 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 553.7 0.0 0.0 0.0 0.3 PSG5 "FL-NCA-3, PSG" ENSG00000204941 "Pregnancy specific beta-1-glycoprotein 5" Q15238 19 43166256-43186536 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 63 "placenta: 111.8" "Cell type enriched" "Detected in some" 44 "Syncytiotrophoblasts: 724.4" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.5" "Region enhanced" "Detected in single" "cerebellum: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BJ: 427.9;fHDF/TERT166: 1485.4" HPA046327 Supported "Secreted in female reproductive system" NA NA 22000000 "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (1.59e-1)" "unprognostic (3.38e-2)" "unprognostic (4.69e-2)" "unprognostic (1.62e-2)" "unprognostic (2.18e-1)" "unprognostic (2.04e-1)" "unprognostic (1.75e-2)" "unprognostic (1.12e-2)" "unprognostic (2.62e-2)" "unprognostic (1.03e-1)" "unprognostic (7.92e-2)" 0.1 0.0 0.2 0.0 0.2 0.0 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.0 111.8 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.0 0.9 0.1 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.3 0.0 0.0 0.2 0.6 0.1 427.9 122.3 7.0 57.8 0.0 0.3 0.0 0.0 1485.4 1.8 16.4 0.1 0.0 65.8 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.1 0.8 0.0 1.1 7.8 2.3 0.0 0.0 0.0 0.0 0.6 1.6 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 10.2 0.0 0.0 0.1 0.5 1.6 54.9 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.7 0.4 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.3 0.0 1.2 0.0 0.1 0.1 0.0 0.5 1.8 0.0 14.2 0.0 0.1 0.0 6.0 0.8 0.0 0.0 0.2 0.0 0.0 3.3 0.0 16.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 3.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.5 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 724.4 0.0 0.1 0.0 0.1 PSMC3IP "GT198, Hop2, HUMGT198A, TBPIP" ENSG00000131470 "PSMC3 interacting protein" Q9P2W1 17 42572310-42577831 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA recombination, Meiosis" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 113.3;Spermatogonia: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA044439 Enhanced Supported Nucleoplasm NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA044439: AB_10964210" "unprognostic (2.98e-1)" "unprognostic (3.66e-1)" "unprognostic (1.33e-1)" "unprognostic (2.87e-1)" "unprognostic (6.59e-2)" "unprognostic (2.39e-2)" "unprognostic (1.28e-7)" "unprognostic (6.22e-2)" "unprognostic (6.14e-2)" "unprognostic (2.47e-1)" "unprognostic (7.26e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (9.41e-4)" "unprognostic (6.03e-2)" "unprognostic (3.68e-1)" "unprognostic (1.39e-2)" "unprognostic (1.82e-1)" 3.3 1.4 8.3 2.5 8.9 8.2 3.8 8.7 10.3 3.5 7.9 4.2 1.3 3.7 3.8 3.0 6.2 1.4 1.8 7.8 8.5 2.8 0.8 2.3 3.9 9.4 8.9 3.4 2.1 7.6 1.5 4.2 9.2 3.6 3.0 7.3 1.5 3.9 1.5 3.1 1.6 5.2 9.0 1.9 2.4 23.7 8.8 7.4 1.8 2.3 5.5 2.9 2.9 8.9 21.1 29.0 48.3 34.9 11.0 15.0 11.0 80.4 23.7 63.4 78.3 28.6 12.9 21.1 17.6 22.2 27.6 29.9 36.9 28.8 73.0 31.0 30.0 13.5 66.1 35.0 1.6 46.3 14.4 5.3 6.4 101.5 34.2 9.4 18.8 28.3 44.5 38.2 56.6 21.8 33.3 28.0 30.0 23.9 26.8 32.3 50.7 20.6 14.8 16.6 65.1 40.6 32.1 11.8 34.7 24.3 28.3 20.3 8.8 70.5 41.1 55.2 128.6 30.0 54.1 30.8 32.8 21.2 79.7 0.0 0.0 0.9 0.7 0.2 0.9 1.1 0.4 0.7 0.0 0.3 0.1 0.4 0.9 0.1 0.3 2.8 0.7 0.1 8.3 8.9 8.7 10.3 7.8 8.5 9.4 8.9 9.2 9.0 8.8 8.9 6.0 3.2 3.7 2.3 6.4 5.4 2.7 3.7 0.0 5.9 4.8 5.2 0.9 4.3 2.8 3.7 10.4 15.6 3.7 1.4 0.0 4.5 12.8 11.1 5.8 4.4 0.0 19.8 1.1 3.3 19.1 5.5 1.5 5.0 1.3 7.7 2.9 2.2 7.4 0.0 1.2 1.2 4.1 3.0 2.6 13.1 5.3 2.4 5.4 2.8 5.8 4.6 3.1 1.0 1.5 2.0 0.3 8.6 6.5 2.0 0.2 2.2 14.9 13.9 19.7 8.6 16.0 113.3 44.6 3.2 4.1 5.2 2.7 2.5 2.5 1.7 PSMD2 "MGC14274, P97, Rpn1, S2, TRAP2" ENSG00000175166 "Proteasome 26S subunit, non-ATPase 2" Q13200 3 184299198-184309050 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 332.9" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 349.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045192, HPA062363" Enhanced NA NA 430000 "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA045192: AB_10961324, HPA062363: " "unprognostic (1.06e-2)" "unprognostic (1.69e-2)" "unprognostic (6.82e-2)" "unprognostic (2.43e-2)" "unprognostic (2.96e-1)" "prognostic unfavorable (9.98e-4)" "prognostic unfavorable (6.63e-7)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.69e-1)" "unprognostic (4.68e-2)" "unprognostic (1.51e-2)" "unprognostic (1.32e-1)" "unprognostic (4.25e-3)" "unprognostic (1.53e-1)" "unprognostic (9.12e-2)" "unprognostic (1.13e-2)" "unprognostic (2.74e-3)" 64.1 102.6 65.0 61.9 67.6 77.8 53.3 68.3 71.7 58.4 65.1 73.2 49.4 69.1 45.5 84.3 53.5 41.3 116.3 67.6 73.7 62.7 68.8 59.3 57.9 74.8 81.1 50.3 48.0 82.9 58.8 58.4 84.6 52.2 63.2 46.9 60.6 59.8 332.9 79.7 55.8 76.7 68.9 59.1 63.4 101.9 73.2 73.4 55.3 183.3 77.1 64.5 58.8 65.2 800.0 248.6 194.3 328.7 226.2 129.6 238.8 478.3 363.6 580.3 327.6 349.1 163.4 251.5 643.4 393.8 467.1 254.3 290.3 516.4 725.0 383.6 234.1 268.4 229.6 211.9 123.7 191.9 211.8 147.3 156.8 549.5 339.0 219.1 353.6 188.9 201.1 226.9 476.0 310.7 199.4 110.1 279.4 290.8 438.1 217.6 287.8 262.9 240.4 248.7 174.5 134.7 376.2 321.3 174.7 208.4 446.5 145.1 463.6 361.2 383.9 293.3 1049.9 219.7 501.3 412.9 438.7 204.2 256.7 48.8 86.0 82.2 61.9 74.5 56.7 59.0 60.1 68.0 103.1 53.5 58.5 56.3 26.6 76.7 79.6 48.3 66.9 96.3 65.0 67.6 68.3 71.7 67.6 73.7 74.8 81.1 84.6 68.9 73.2 65.2 49.0 67.3 61.7 13.4 53.4 71.1 66.2 101.1 58.1 66.9 38.7 31.5 113.3 38.6 81.8 57.0 20.9 153.8 60.6 67.3 90.1 183.2 161.8 56.1 55.0 63.0 79.6 105.9 21.0 130.8 117.9 60.3 45.3 61.3 40.5 111.3 35.0 60.5 83.8 72.3 20.0 40.0 79.3 38.8 54.0 90.3 48.7 58.5 53.4 15.9 94.1 117.1 51.5 12.5 16.6 349.2 33.3 65.8 84.4 63.1 59.1 97.0 71.5 60.5 32.9 48.2 183.0 184.6 138.9 65.2 67.1 222.9 53.0 94.3 55.8 57.7 PTGS2 COX2 ENSG00000073756 "Prostaglandin-endoperoxide synthase 2" P35354 1 186671791-186680922 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 116.7;seminal vesicle: 127.4;urinary bladder: 162.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 342.9;Fibroblasts: 270.7;granulocytes: 347.6;Langerhans cells: 305.6;Macrophages: 173.1;Urothelial cells: 151.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "neutrophil: 11.7" "Lineage enriched" "Detected in single" 16 "granulocytes: 11.7" "Cell line enriched" "Detected in many" 4 "BJ hTERT+: 405.5" "Region enhanced" "Detected in many" "hippocampal formation: 15.1" "Low region specificity" "Detected in many" "CAB000113, HPA001335" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "CAB000113: , HPA001335: AB_1079712" "unprognostic (1.36e-3)" "unprognostic (9.97e-3)" "unprognostic (3.97e-2)" "unprognostic (3.31e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (5.96e-2)" "unprognostic (9.50e-2)" "unprognostic (9.03e-3)" "unprognostic (2.81e-1)" "unprognostic (3.24e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (8.04e-3)" "unprognostic (4.38e-2)" "unprognostic (8.89e-2)" "unprognostic (3.74e-2)" 17.0 7.9 1.4 13.9 2.5 116.7 3.0 1.1 4.1 62.2 2.7 14.9 2.6 8.9 0.7 6.9 5.1 31.6 11.7 1.9 1.4 10.2 8.0 34.3 8.9 2.0 1.6 2.6 2.2 5.6 3.1 8.4 1.5 25.0 9.9 0.3 1.2 127.4 0.4 1.6 3.6 12.2 1.9 2.8 14.8 0.2 1.8 5.2 3.2 6.5 0.6 162.5 2.2 2.6 0.0 21.8 0.1 0.0 2.5 2.1 0.0 93.4 405.5 0.6 3.6 15.0 17.2 0.0 0.0 0.1 2.5 12.2 0.0 7.6 1.3 0.0 0.0 0.8 2.2 0.0 13.2 0.0 0.2 0.8 2.7 11.3 28.7 1.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 5.5 1.5 0.0 1.0 0.0 0.9 2.7 0.0 0.1 1.5 19.3 0.6 13.5 0.6 0.2 0.0 0.0 27.7 0.4 2.3 0.0 0.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 11.7 0.0 0.4 0.0 0.0 0.0 1.4 2.5 1.1 4.1 1.9 1.4 2.0 1.6 1.5 1.9 1.8 2.6 5.2 342.9 77.7 0.0 7.4 118.8 59.1 72.8 12.5 0.0 2.6 12.8 2.5 0.0 79.7 0.0 0.0 0.2 4.2 0.3 0.0 0.8 0.2 50.0 9.9 31.1 1.2 3.6 3.8 0.2 0.3 270.7 2.0 98.9 347.6 3.8 13.6 0.2 12.1 0.0 1.0 1.0 8.2 21.0 305.6 0.0 0.0 173.1 35.6 3.7 3.4 0.1 0.0 0.0 0.1 4.9 0.1 0.0 2.0 122.6 0.2 0.3 13.1 0.3 0.0 1.8 12.8 0.1 0.4 3.3 28.4 0.5 10.8 3.7 1.2 151.6 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase non-receptor type 11" Q06124 12 112418351-112509918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli rim,Actin filaments,Cytosol" NA NA 74000 "Cluster 6: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Nucleoli rim" "Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 62.9 36.6 74.6 34.7 91.7 46.3 37.6 72.7 115.7 37.9 38.4 32.5 27.6 37.8 28.7 38.9 24.3 29.4 68.7 66.1 85.6 39.7 53.0 34.4 35.6 79.0 84.1 26.2 31.6 53.4 16.1 38.0 85.7 35.2 30.6 51.8 25.9 42.4 75.1 32.1 26.1 45.7 83.4 26.7 30.4 18.2 81.7 35.5 46.8 64.0 32.5 40.1 23.5 106.3 116.9 107.6 77.0 73.4 109.7 106.1 92.7 136.4 148.2 105.5 78.5 107.7 43.4 124.5 69.4 127.4 66.7 68.1 100.1 121.6 173.8 93.1 85.0 181.5 102.6 59.8 109.2 145.8 108.0 86.6 119.6 113.6 159.8 101.3 88.7 92.0 140.2 41.3 103.3 83.2 101.0 69.7 94.1 112.3 73.4 102.4 114.6 70.5 97.3 126.7 53.3 66.1 133.7 99.8 85.2 77.6 114.8 97.8 108.1 122.9 110.0 74.2 121.8 79.4 141.6 120.2 102.2 99.7 117.7 32.2 11.7 16.8 14.8 10.2 14.0 18.1 13.3 12.4 13.6 20.8 15.3 11.9 10.7 12.6 13.7 18.3 10.9 7.2 74.6 91.7 72.7 115.7 66.1 85.6 79.0 84.1 85.7 83.4 81.7 106.3 49.0 60.9 68.2 27.7 25.8 25.6 39.9 25.3 20.5 29.9 40.5 32.4 131.6 24.3 41.8 36.8 16.7 23.5 34.2 25.4 33.2 37.5 63.1 31.3 92.6 46.2 13.1 21.7 67.6 42.8 25.3 35.8 21.9 40.9 28.4 33.1 26.0 101.5 26.8 13.5 54.7 22.0 18.3 33.3 21.6 28.5 51.6 31.8 14.2 40.3 31.1 59.8 29.9 32.6 73.0 59.3 19.6 79.7 37.0 73.4 16.6 39.8 23.5 22.2 32.9 58.2 49.2 7.1 6.6 37.5 27.4 35.2 31.7 30.5 22.2 66.8 PTPN14 PEZ ENSG00000152104 "Protein tyrosine phosphatase non-receptor type 14" Q15678 1 214348700-214552449 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011469, HPA053864, CAB069441" Uncertain Supported Nucleoplasm NA NA "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB011469: AB_299202, CAB069441: , HPA053864: AB_2682281" "unprognostic (1.54e-1)" "unprognostic (8.19e-2)" "unprognostic (5.42e-5)" "unprognostic (1.42e-1)" "unprognostic (2.91e-1)" "unprognostic (5.97e-2)" "unprognostic (1.26e-1)" "unprognostic (1.58e-1)" "unprognostic (2.84e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.29e-4)" "unprognostic (7.43e-2)" "unprognostic (8.34e-3)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "unprognostic (4.81e-3)" 7.5 8.0 3.7 1.8 1.5 0.2 10.6 1.5 3.7 5.2 13.4 7.6 0.9 8.2 2.5 6.0 7.3 3.3 6.0 3.3 0.8 8.2 0.7 4.6 1.3 2.4 2.4 6.6 4.3 3.3 1.8 7.8 2.1 6.7 2.3 0.6 6.5 6.6 19.8 16.2 2.8 7.9 1.4 3.5 4.5 3.9 4.2 2.1 5.3 10.2 1.8 5.6 5.6 1.9 21.1 9.2 7.2 10.6 12.3 20.9 21.6 23.2 21.3 17.3 14.4 18.8 10.7 0.1 25.3 53.6 10.0 18.1 10.0 25.7 29.0 0.2 7.7 1.9 26.6 3.5 22.2 0.2 1.0 15.6 26.1 30.0 47.4 28.1 33.8 0.6 0.1 0.2 41.8 2.3 0.2 0.2 16.2 3.7 9.9 0.3 36.3 0.1 30.6 10.5 0.1 1.7 28.7 18.4 11.6 25.1 18.4 0.7 61.4 40.3 15.9 14.6 33.3 1.2 0.1 0.2 21.6 0.3 34.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 3.7 1.5 1.5 3.7 3.3 0.8 2.4 2.4 2.1 1.4 4.2 1.9 60.3 73.7 12.6 47.3 1.3 56.5 32.1 39.4 45.5 0.6 20.3 29.8 20.5 14.3 32.7 29.5 0.0 38.8 1.3 1.0 7.9 12.9 8.8 42.5 25.9 53.5 3.5 0.0 47.9 11.0 14.2 20.8 9.2 55.2 1.3 13.5 40.0 0.9 4.5 0.0 6.0 4.1 4.1 1.5 7.7 4.4 26.1 2.4 10.6 91.8 0.3 3.9 3.1 39.2 2.1 31.2 0.3 29.3 1.6 30.6 0.3 14.4 18.5 1.3 19.7 38.0 20.1 1.2 10.6 18.3 36.1 24.2 3.7 46.3 2.9 28.9 PVR "CD155, HVED, Necl-5, NECL5, PVS, Tage4" ENSG00000073008 "PVR cell adhesion molecule" P15151 19 44643798-44666162 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 4.5;intermediate monocyte: 4.5;myeloid DC: 3.8;non-classical monocyte: 5.5" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;monocytes: 5.5" "Cell line enhanced" "Detected in many" "TIME: 175.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012568, HPA064739" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Secreted - unknown location" NA NA 720000000 "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles, Plasma membrane" "HPA012568: AB_1846248, HPA064739: " "unprognostic (2.90e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.36e-1)" "unprognostic (2.34e-1)" "unprognostic (7.89e-2)" "unprognostic (2.45e-3)" "unprognostic (3.06e-2)" "prognostic unfavorable (9.30e-4)" "unprognostic (9.05e-3)" "unprognostic (1.69e-1)" "unprognostic (2.09e-3)" "unprognostic (2.64e-3)" "unprognostic (1.69e-1)" "unprognostic (4.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-3)" "prognostic unfavorable (2.75e-4)" 13.9 17.5 10.2 7.1 9.1 5.1 9.6 9.0 10.0 8.7 9.3 10.3 12.5 13.9 5.2 8.4 11.8 6.2 28.5 9.0 16.6 13.6 30.7 19.4 2.7 9.7 11.0 12.5 14.0 10.3 17.3 12.5 12.4 9.7 8.8 5.4 9.9 6.4 19.0 7.1 11.1 10.5 7.4 4.6 12.3 5.8 14.9 2.5 10.6 6.2 2.8 9.1 8.5 7.9 58.8 52.1 5.6 25.0 8.6 9.7 7.4 96.7 38.8 40.7 45.8 31.9 28.2 0.1 50.6 43.7 60.2 44.4 24.3 51.1 31.7 7.8 27.1 8.8 40.3 23.3 43.7 4.1 22.2 10.6 28.0 40.9 82.5 49.7 50.7 6.6 4.3 0.5 23.4 7.8 4.2 5.8 12.5 30.1 31.7 0.1 23.2 5.0 111.8 25.5 21.2 22.9 66.3 54.3 14.7 7.2 22.8 12.5 175.3 39.0 52.8 33.7 78.2 0.3 6.3 0.2 35.3 23.4 24.6 0.2 4.5 0.0 0.1 4.5 0.0 0.0 0.0 0.2 3.8 0.0 0.2 0.1 1.1 0.7 5.5 0.5 0.0 1.7 10.2 9.1 9.0 10.0 9.0 16.6 9.7 11.0 12.4 7.4 14.9 7.9 11.1 16.0 25.2 2.3 1.6 3.6 16.0 6.9 4.0 5.7 4.7 3.4 14.4 14.3 12.2 1.8 2.1 2.9 0.2 18.5 3.9 37.9 10.5 5.4 6.3 20.4 13.1 2.1 11.4 35.3 34.8 7.7 13.7 11.6 1.3 6.5 7.9 41.1 8.4 1.7 13.7 11.3 2.0 8.9 7.5 14.3 5.6 6.8 1.8 5.6 17.2 1.8 2.1 6.0 4.6 69.6 18.0 15.8 0.2 14.4 10.8 5.7 2.8 3.4 0.0 23.8 10.4 10.4 1.5 5.8 5.5 1.0 0.9 10.8 12.7 7.4 PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.1;Endometrial stromal cells: 99.4;Endothelial cells: 95.1;Hepatic stellate cells: 71.4;Skeletal myocytes: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 323.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA012375 Approved "Secreted to extracellular matrix" NA NA 9100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA012375: AB_1855965" "unprognostic (4.37e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (8.16e-3)" "unprognostic (1.91e-1)" "unprognostic (1.92e-2)" "unprognostic (3.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.34e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.18e-1)" "unprognostic (7.33e-3)" "unprognostic (5.54e-3)" 59.5 5.5 4.1 24.3 3.5 0.9 33.7 1.9 4.1 18.2 27.5 36.1 7.9 32.8 4.0 4.9 18.0 22.7 22.7 3.1 7.7 9.0 12.4 27.6 5.0 4.2 6.2 32.7 3.8 3.0 11.7 33.4 4.7 17.5 8.7 5.2 13.6 11.1 7.7 6.9 16.3 61.8 2.6 10.0 13.2 6.4 5.2 2.1 8.4 11.5 2.1 33.8 13.5 3.4 39.9 13.9 72.0 0.1 198.3 180.9 54.6 231.4 182.3 99.0 107.9 0.1 0.5 0.0 323.8 230.3 4.5 8.3 0.3 142.3 125.5 0.6 2.4 0.0 139.3 0.0 196.4 0.6 0.0 200.7 41.0 112.2 83.8 299.5 247.0 35.9 0.1 0.0 142.6 23.6 6.8 8.0 58.3 0.0 52.3 13.2 250.8 0.6 115.9 0.1 0.2 131.9 0.2 73.6 0.4 142.9 27.0 0.9 242.4 162.8 79.7 6.2 180.7 0.2 205.4 1.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.1 3.5 1.9 4.1 3.1 7.7 4.2 6.2 4.7 2.6 5.2 3.4 79.1 6.4 2.3 2.6 0.4 2.9 2.8 12.8 0.6 2.5 17.5 14.1 5.8 17.2 7.0 1.8 0.0 0.6 0.2 0.3 0.0 10.4 33.4 4.2 99.4 95.1 1.8 0.0 6.6 0.0 11.3 45.2 0.0 3.4 1.3 43.7 71.4 1.8 1.9 0.0 7.3 1.3 20.3 5.7 4.4 40.7 26.8 0.7 7.2 8.4 0.6 10.0 1.0 55.8 0.7 0.5 0.1 15.1 0.0 14.0 0.0 0.2 6.7 0.8 46.0 120.1 51.1 22.0 16.0 0.5 2.8 1.4 1.0 33.3 0.5 1.4 QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 1616.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1918.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 2600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA056243: AB_2683077" "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" 84.8 84.9 35.8 52.1 39.4 115.5 53.2 42.7 47.3 81.7 41.1 100.1 67.5 75.2 70.2 178.4 82.3 150.3 244.9 41.5 43.4 73.8 81.7 200.0 16.3 50.0 40.7 196.1 136.3 21.0 60.2 158.9 43.2 92.3 80.9 15.2 105.6 57.5 91.2 58.6 85.7 60.0 44.0 61.9 178.3 172.9 42.6 12.1 31.9 46.0 19.6 174.1 108.7 57.7 441.4 62.0 14.8 181.0 179.1 367.8 712.5 456.5 456.6 381.6 267.1 7.3 137.7 6.8 276.7 367.8 52.6 93.7 17.6 123.5 185.0 26.4 28.0 14.1 33.6 19.4 1918.6 48.6 129.2 197.9 55.5 408.0 484.3 499.9 569.4 32.1 20.2 66.3 255.3 76.4 10.4 89.7 49.4 302.6 174.6 19.7 33.0 11.8 63.1 123.6 51.9 52.6 133.8 179.8 91.9 32.2 33.0 226.3 678.3 473.8 187.5 322.0 392.9 48.3 84.4 12.2 180.9 153.9 146.0 16.2 53.1 20.6 14.0 29.9 10.2 5.4 9.1 9.6 39.2 3.2 8.1 8.0 40.2 16.9 28.6 8.0 11.5 28.6 35.8 39.4 42.7 47.3 41.5 43.4 50.0 40.7 43.2 44.0 42.6 57.7 36.6 57.7 101.6 8.5 7.7 13.8 27.4 81.2 7.4 11.5 86.2 47.9 48.3 51.5 112.5 71.7 25.0 19.5 10.7 138.1 0.0 230.4 49.2 49.2 19.4 41.7 46.2 6.9 17.2 130.1 1616.7 78.0 136.6 80.4 25.4 27.1 89.3 4.3 68.6 6.7 17.0 185.7 132.2 45.2 35.3 20.1 177.7 48.9 44.4 8.4 49.7 53.5 10.3 24.6 23.9 249.8 165.6 71.1 12.8 35.7 9.0 9.1 47.8 6.7 32.9 13.6 31.3 30.2 32.7 10.2 9.9 154.3 13.9 13.9 89.9 68.0 RAB3B ENSG00000169213 "RAB3B, member RAS oncogene family" P20337 1 51907956-51990700 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 31.0;pituitary gland: 10.6;prostate: 11.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Alveolar cells type 2: 103.2;Enteroendocrine cells: 293.8;Pancreatic endocrine cells: 92.8" "Group enriched" "Detected in many" 6 "prostate cancer: 19.4;testis cancer: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 125.8;BJ hTERT+: 48.4;fHDF/TERT166: 45.8;TIME: 97.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003159, CAB023293" Enhanced Approved "Cell Junctions" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Cell Junctions" "CAB023293: , HPA003159: AB_1856005" "unprognostic (1.10e-1)" "unprognostic (2.20e-3)" "unprognostic (5.43e-3)" "unprognostic (1.65e-2)" "unprognostic (1.82e-1)" "unprognostic (1.38e-2)" "unprognostic (1.20e-2)" "unprognostic (8.77e-3)" "unprognostic (2.79e-1)" "unprognostic (2.81e-1)" "unprognostic (2.42e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-2)" "unprognostic (2.02e-3)" "unprognostic (1.06e-1)" "unprognostic (1.05e-1)" "unprognostic (1.15e-2)" 0.0 3.0 11.3 0.6 8.6 0.2 0.7 2.9 14.9 0.0 0.0 1.6 0.7 0.1 0.2 0.0 0.2 1.3 0.0 10.9 23.0 0.5 0.7 0.0 0.1 11.4 17.5 1.5 1.0 0.0 10.6 1.6 31.0 11.0 2.3 1.7 0.2 0.1 0.5 1.9 0.9 0.3 2.3 0.1 1.2 0.3 19.5 0.2 0.0 0.0 0.1 0.1 0.1 3.4 1.8 8.5 1.2 1.3 0.2 2.3 0.2 125.8 48.4 24.8 12.0 10.4 3.7 0.6 2.0 45.8 3.6 0.1 15.4 13.0 41.7 0.0 1.1 0.1 0.6 3.4 2.1 0.0 0.1 1.1 0.4 41.1 9.4 15.4 7.8 1.1 0.4 0.4 27.9 0.3 0.1 0.1 19.9 2.4 1.2 0.3 0.2 0.2 4.0 0.8 4.3 1.1 0.1 0.3 0.1 24.6 0.2 0.3 97.9 24.0 8.8 0.5 41.5 0.2 0.6 0.4 21.9 0.1 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 11.3 8.6 2.9 14.9 10.9 23.0 11.4 17.5 31.0 2.3 19.5 3.4 1.4 147.4 103.2 0.3 1.1 2.4 6.2 0.3 0.0 5.0 2.2 3.4 0.7 12.8 27.9 0.0 2.1 0.5 0.4 2.0 3.9 4.0 2.4 1.5 1.3 8.2 293.8 0.0 6.6 18.4 0.3 13.9 3.6 1.4 7.6 27.9 0.7 2.7 0.3 0.0 48.1 14.7 14.2 1.3 1.2 1.3 0.6 3.7 1.8 1.0 1.0 31.2 1.0 1.5 1.5 92.8 1.4 1.2 2.3 18.8 1.4 0.2 29.5 3.7 0.0 4.1 4.8 10.4 4.3 0.0 1.4 4.0 3.3 1.1 1.6 2.7 RABGEF1 "rabex-5, RABEX5" ENSG00000154710 "RAB guanine nucleotide exchange factor 1" Q9UJ41 7 66682164-66811464 "Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 76.7" "Cell type enhanced" "Detected in many" "Astrocytes: 91.4;Excitatory neurons: 124.5;Inhibitory neurons: 151.1;Oligodendrocyte precursor cells: 100.5;Oligodendrocytes: 244.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001407 Supported Nucleoli,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Nucleoli "HPA001407: AB_1856024" "unprognostic (6.65e-2)" "unprognostic (6.44e-4)" "unprognostic (7.32e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (4.06e-5)" "unprognostic (3.77e-1)" "unprognostic (2.08e-2)" "unprognostic (1.41e-1)" "unprognostic (8.51e-2)" "unprognostic (3.32e-1)" "unprognostic (4.64e-4)" "unprognostic (6.45e-2)" "prognostic favorable (1.27e-4)" "unprognostic (1.43e-1)" "unprognostic (5.55e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" 16.2 14.1 15.0 11.2 14.9 76.7 13.0 14.9 18.8 13.1 15.6 10.7 8.0 11.5 10.0 19.6 8.8 14.2 9.8 15.2 16.1 11.5 14.8 10.5 11.5 15.6 14.7 12.0 9.7 14.8 4.4 13.2 15.3 12.0 11.9 49.8 8.6 17.3 13.0 23.9 9.2 12.4 14.3 9.4 10.5 25.1 15.5 13.2 15.9 13.3 16.9 19.1 14.1 17.6 47.5 10.2 10.0 16.9 32.1 45.2 10.4 40.9 52.8 42.6 40.2 12.2 28.5 22.4 13.9 60.7 28.2 17.7 16.8 22.3 59.0 14.9 11.2 12.5 14.6 11.8 25.5 21.5 16.9 22.2 28.5 54.9 60.4 33.2 11.3 13.7 21.6 13.9 42.9 19.2 13.2 27.7 15.0 20.2 19.3 12.2 20.1 14.7 37.4 19.5 12.2 17.8 16.8 37.5 19.6 15.6 19.4 12.3 14.0 65.8 12.2 42.4 32.0 19.8 28.7 25.1 31.6 23.0 18.6 18.3 6.5 7.8 7.4 5.7 8.1 9.1 6.3 8.9 6.1 12.5 6.3 6.3 11.8 13.8 12.9 8.1 5.1 6.4 15.0 14.9 14.9 18.8 15.2 16.1 15.6 14.7 15.3 14.3 15.5 17.6 7.3 12.8 12.8 91.4 11.5 4.1 11.4 3.2 10.2 9.9 11.5 7.7 4.8 4.3 10.9 5.5 16.7 3.8 13.2 10.0 11.7 5.4 5.4 13.6 12.5 5.7 18.0 3.0 124.5 5.5 3.8 14.6 8.6 22.0 14.0 8.8 5.7 8.0 4.8 8.4 151.1 4.3 2.0 15.2 5.0 2.8 5.9 19.9 1.8 60.9 6.2 5.5 7.2 100.5 244.1 18.1 13.4 9.4 15.2 13.4 4.4 5.5 11.9 18.9 0.0 10.6 8.5 8.4 6.5 8.3 6.7 13.5 9.5 7.0 5.5 12.3 RAD21L1 "dJ545L17.2, RAD21L" ENSG00000244588 "RAD21 cohesin complex component like 1" Q9H4I0 20 1226056-1296421 "Predicted intracellular proteins" "Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "testis: 11.5" "Group enriched" "Detected in some" 14 "Early spermatids: 110.9;Late spermatids: 109.4;Spermatocytes: 29.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.5;TIME: 1.5" "Low region specificity" "Detected in some" HPA053282 Approved NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "HPA053282: AB_2682099" "unprognostic (2.90e-1)" "unprognostic (3.35e-1)" "unprognostic (1.62e-4)" "unprognostic (2.04e-1)" "unprognostic (8.87e-4)" "unprognostic (1.15e-1)" "unprognostic (1.25e-1)" "unprognostic (1.84e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 1.5 0.8 0.3 0.0 0.0 0.0 0.1 0.2 0.6 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 110.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 109.4 0.6 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.4 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RANGAP1 "Fug1, KIAA1835, SD" ENSG00000100401 "Ran GTPase activating protein 1" P46060 22 41244779-41286187 "Plasma proteins, Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1717.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004293, HPA050110, HPA062034" Supported Enhanced "Nuclear membrane,Vesicles,Cytosol" Yes Yes 75000 "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" "Vesicles, Cytosol" "CAB004293: AB_2176987, HPA050110: AB_2681018, HPA062034: AB_2684667" "unprognostic (1.30e-2)" "unprognostic (3.16e-2)" "unprognostic (1.66e-1)" "unprognostic (7.97e-2)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.28e-3)" "unprognostic (8.09e-2)" "unprognostic (9.87e-2)" "unprognostic (5.84e-2)" "unprognostic (7.56e-2)" "unprognostic (7.07e-3)" "prognostic favorable (5.39e-4)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-1)" 27.5 72.9 78.2 26.0 86.0 48.1 29.6 70.8 102.3 34.4 47.7 29.2 18.1 24.9 12.0 79.8 23.6 17.2 45.1 79.5 85.2 43.9 88.0 41.6 30.6 102.7 77.9 32.5 60.9 12.7 57.4 22.8 105.1 39.3 13.2 32.7 38.0 17.6 43.0 96.9 30.6 17.5 68.7 42.3 39.6 178.1 82.0 40.4 34.4 14.2 31.8 34.7 45.4 109.1 228.0 112.2 75.9 77.3 38.8 31.4 85.9 194.5 103.8 182.8 98.4 135.9 71.9 118.0 154.0 137.4 94.8 203.0 135.5 145.4 125.2 95.7 199.2 103.3 115.0 107.9 46.7 171.6 72.5 30.0 69.5 132.2 123.4 67.6 102.1 45.0 127.7 83.3 111.9 186.1 96.3 130.0 84.5 217.6 127.6 118.8 73.4 126.0 72.5 123.7 66.6 44.1 139.1 117.7 71.7 74.6 72.2 64.4 146.5 141.7 138.5 78.6 154.6 60.1 92.8 124.2 99.3 119.3 82.0 2.7 7.6 6.9 8.1 9.0 9.5 5.9 8.2 7.8 5.6 6.4 7.4 5.9 2.0 5.9 12.9 5.9 9.5 8.2 78.2 86.0 70.8 102.3 79.5 85.2 102.7 77.9 105.1 68.7 82.0 109.1 10.9 3.2 20.9 8.5 15.0 23.1 22.2 10.9 18.2 16.0 22.4 16.9 19.6 25.8 9.6 9.2 14.6 22.7 20.3 22.9 3.9 33.3 270.7 21.0 14.7 16.1 25.0 16.6 28.3 20.3 35.3 13.3 25.5 25.1 6.3 74.4 8.9 21.8 16.6 15.2 20.8 19.1 16.2 13.9 20.9 1717.0 14.9 16.8 12.4 5.6 8.9 10.1 14.4 6.0 32.2 39.8 5.7 12.0 25.8 37.4 7.1 13.1 11.4 26.4 0.0 6.8 18.2 25.6 17.7 38.8 31.0 23.7 24.3 42.5 24.8 23.3 RAPH1 "ALS2CR18, ALS2CR9, KIAA1681" ENSG00000173166 "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1" Q70E73 2 203394345-203535335 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 84.0;Hepatic stellate cells: 103.5;Microglial cells: 92.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016744, HPA020027" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 69000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Nuclear bodies, Plasma membrane" Cytosol "HPA016744: AB_1844781, HPA020027: AB_1844782" "unprognostic (9.78e-2)" "unprognostic (9.05e-2)" "unprognostic (7.17e-4)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (8.32e-2)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.24e-4)" "unprognostic (1.92e-1)" "unprognostic (1.40e-2)" "unprognostic (5.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (2.79e-1)" 11.1 6.5 1.5 5.2 4.6 3.1 13.3 1.3 7.9 9.4 0.3 7.0 7.8 5.6 4.6 8.8 5.1 8.9 5.9 5.0 8.5 7.2 61.6 14.3 3.7 2.4 7.0 2.0 6.4 5.6 3.6 13.0 4.1 6.6 7.3 7.3 8.6 4.3 6.6 8.9 7.9 7.8 0.1 16.9 8.8 9.4 2.7 2.6 30.0 6.2 4.9 7.7 6.6 2.2 11.1 7.5 15.6 9.0 12.0 15.4 14.7 15.1 11.0 15.3 19.1 35.0 11.4 0.0 3.7 23.1 11.2 5.8 8.2 12.9 31.7 2.2 4.6 0.0 17.9 6.2 30.0 0.1 0.2 21.5 10.7 28.1 29.4 16.8 24.2 1.7 0.8 8.2 31.0 6.2 0.1 0.0 9.2 5.7 10.0 0.2 22.0 6.9 11.2 34.9 5.5 7.5 10.3 9.8 12.5 20.4 5.5 0.5 29.0 37.5 12.5 18.2 16.1 3.8 7.7 0.1 30.9 0.2 8.4 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.1 0.0 1.5 4.6 1.3 7.9 5.0 8.5 2.4 7.0 4.1 0.1 2.7 2.2 36.3 16.0 8.4 12.7 1.2 49.1 20.7 10.3 16.5 11.3 21.6 9.4 1.1 15.7 9.7 14.7 14.6 8.9 0.8 32.9 7.9 6.3 14.4 24.4 17.7 29.0 2.4 3.2 84.0 9.3 7.6 23.4 47.9 65.7 1.3 6.2 103.5 79.6 18.1 10.1 56.7 8.6 4.1 17.8 51.1 4.9 4.7 28.8 12.4 92.8 3.3 18.6 0.0 41.2 9.1 20.5 21.3 4.9 0.1 19.0 22.4 2.8 5.2 4.4 19.7 26.8 33.4 29.3 19.6 26.9 40.9 10.9 2.8 0.9 13.3 28.4 RASA2 GAP1M ENSG00000155903 "RAS p21 protein activator 2" Q15283 3 141487027-141615344 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 196.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035374, HPA035375" Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Vesicles "HPA035374: AB_10602122, HPA035375: AB_2674596" "unprognostic (1.85e-1)" "unprognostic (8.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.38e-2)" "unprognostic (1.18e-1)" "unprognostic (3.36e-3)" "unprognostic (9.62e-3)" "unprognostic (2.57e-1)" "unprognostic (1.38e-1)" "unprognostic (9.21e-2)" "unprognostic (4.23e-2)" "unprognostic (8.93e-2)" "prognostic unfavorable (7.62e-7)" "unprognostic (1.17e-1)" "unprognostic (2.56e-1)" "unprognostic (1.61e-1)" "prognostic favorable (4.34e-5)" 7.3 4.7 5.1 15.4 6.0 21.9 10.0 7.1 6.4 9.8 3.2 6.6 5.3 8.4 7.3 7.3 7.8 6.7 4.6 5.3 4.9 5.8 5.1 9.7 21.3 4.0 3.6 9.7 5.2 4.4 6.2 8.3 3.5 6.5 7.2 14.6 8.1 5.0 3.8 11.2 8.5 6.0 3.1 12.4 5.4 4.7 4.7 13.3 6.0 3.3 17.2 8.8 8.8 5.6 24.6 4.5 9.5 7.2 10.2 12.6 13.5 17.4 34.0 11.0 13.5 10.5 7.9 15.6 11.7 15.2 10.6 10.0 6.8 7.5 20.0 8.5 6.7 8.4 3.8 3.8 5.4 16.1 21.0 7.3 6.6 10.0 11.8 13.3 14.1 13.1 7.7 19.7 11.0 3.6 21.2 13.0 11.1 8.1 3.2 7.9 16.0 19.5 10.9 8.7 3.3 6.9 13.8 12.1 13.0 9.8 6.0 12.0 11.9 12.9 5.9 18.1 7.8 31.9 10.0 20.9 11.3 10.8 6.4 12.8 4.9 5.3 14.8 5.0 14.8 8.9 13.2 15.3 4.6 13.5 21.6 17.2 19.2 15.7 8.9 3.6 13.2 8.0 5.1 6.0 7.1 6.4 5.3 4.9 4.0 3.6 3.5 3.1 4.7 5.6 24.2 44.8 23.6 59.4 55.1 21.5 52.0 15.8 21.1 16.2 22.0 17.5 7.4 8.6 21.4 12.9 37.5 20.0 104.9 21.7 1.9 16.8 120.3 26.3 19.7 22.7 15.7 17.5 196.9 16.5 6.6 20.4 11.2 60.7 31.6 29.6 20.3 9.6 12.5 30.3 123.1 15.2 8.2 32.5 24.6 12.7 13.7 34.3 12.4 94.6 19.8 15.3 68.0 112.1 94.4 31.8 21.7 14.3 94.9 53.4 10.4 9.1 15.5 50.7 6.6 26.4 27.2 28.2 15.3 17.5 27.4 13.1 88.3 4.6 18.7 62.5 RASA4 "CAPRI, GAPL, KIAA0538" ENSG00000105808 "RAS p21 protein activator 4" O43374 7 102573807-102616756 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 254.9;tongue: 88.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 73.9;Enteroendocrine cells: 71.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 48.9" HPA043010 Uncertain Approved "Vesicles,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 56: Bipolar cells - Visual perception" Vesicles "Cell Junctions" "HPA043010: AB_2678267" "unprognostic (6.44e-2)" "unprognostic (3.64e-2)" "unprognostic (8.93e-3)" "unprognostic (1.69e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (3.44e-1)" "unprognostic (7.45e-2)" "unprognostic (2.92e-1)" "unprognostic (2.29e-1)" "unprognostic (4.62e-3)" "unprognostic (4.19e-2)" "unprognostic (4.81e-2)" "unprognostic (8.87e-3)" "unprognostic (2.47e-2)" "unprognostic (3.34e-1)" "unprognostic (1.18e-2)" 38.9 17.5 22.9 10.8 18.8 6.0 31.2 22.7 23.0 37.4 3.6 29.8 10.9 37.7 4.7 10.8 28.4 6.3 14.5 22.5 22.8 29.2 2.6 22.1 13.8 21.5 25.9 25.2 12.3 12.8 24.2 13.0 17.3 23.4 4.0 13.3 12.9 18.0 254.9 17.3 21.6 7.5 17.2 16.8 16.1 5.4 22.7 4.8 17.3 88.6 7.1 26.0 29.0 16.3 1.1 1.5 14.1 2.6 1.8 5.8 0.6 16.3 7.6 4.3 4.9 6.1 3.1 9.9 11.9 24.0 0.3 12.7 0.6 0.1 1.7 1.7 2.4 3.2 4.1 1.0 2.1 2.0 4.4 6.4 1.4 1.4 0.4 18.7 2.7 6.5 5.9 17.0 1.4 4.0 8.6 7.1 1.0 6.6 7.3 17.5 2.9 16.5 0.4 5.0 12.7 25.3 2.3 2.3 1.9 7.5 1.1 5.7 3.0 48.9 22.3 4.9 4.1 28.9 18.5 7.7 4.3 4.5 5.9 0.4 7.9 0.2 1.3 8.6 3.0 3.2 2.4 1.8 10.9 2.9 2.5 1.5 1.8 1.4 1.1 9.2 3.3 3.8 22.9 18.8 22.7 23.0 22.5 22.8 21.5 25.9 17.3 17.2 22.7 16.3 26.8 12.8 10.9 15.0 8.3 3.8 4.5 1.3 0.6 73.9 2.0 3.0 1.1 2.8 5.2 3.7 16.7 0.2 7.2 5.9 13.7 1.1 0.4 3.3 13.0 24.9 71.8 5.7 5.6 0.7 0.2 5.0 3.1 2.9 1.3 13.6 3.3 1.4 6.0 28.6 6.6 11.8 0.0 11.6 22.8 0.3 8.4 13.3 1.8 4.7 14.2 9.4 6.2 5.5 1.4 1.7 2.8 7.9 4.0 2.9 19.9 8.4 6.2 11.7 13.1 21.3 10.0 3.4 3.3 1.3 3.4 0.4 6.4 5.6 2.9 4.1 RASA4B ENSG00000170667 "RAS p21 protein activator 4B" C9J798 7 102479976-102517777 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "skeletal muscle: 130.9" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Bipolar cells: 3.3;Cardiomyocytes: 3.9;Gastric mucus-secreting cells: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.2;intermediate monocyte: 2.0;myeloid DC: 3.3;plasmacytoid DC: 2.1" "Group enriched" "Detected in many" 6 "dendritic cells: 3.3;monocytes: 2.2" "Cell line enhanced" "Detected in many" "SH-SY5Y: 15.1;U-138 MG: 17.0;U-2 OS: 14.9" "Low region specificity" "Detected in all" HPA043010 Uncertain Approved "Vesicles,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Vesicles "Cell Junctions" "HPA043010: AB_2678267" "unprognostic (1.05e-2)" "unprognostic (1.34e-2)" "unprognostic (1.03e-2)" "unprognostic (1.96e-1)" "unprognostic (1.42e-2)" "unprognostic (1.40e-1)" "unprognostic (4.15e-2)" "unprognostic (1.55e-1)" "unprognostic (2.10e-1)" "unprognostic (6.79e-2)" "unprognostic (3.08e-3)" "unprognostic (2.31e-1)" "unprognostic (5.44e-4)" "unprognostic (1.18e-2)" "unprognostic (3.77e-2)" "unprognostic (4.37e-3)" "unprognostic (1.10e-1)" 14.0 5.8 6.5 4.2 6.1 2.2 10.8 6.3 7.9 13.3 3.0 11.9 6.4 16.5 1.3 2.8 9.7 3.7 4.7 6.2 8.0 6.4 0.8 6.0 4.7 7.8 8.3 9.6 2.4 5.2 5.8 4.9 6.7 8.1 1.8 5.3 4.5 7.6 130.9 5.5 7.8 3.8 6.6 5.9 4.9 2.1 7.6 1.9 3.8 19.2 2.8 9.5 9.5 7.5 0.2 1.4 3.7 0.5 1.3 2.9 0.2 6.8 4.4 2.2 3.6 0.5 1.1 3.4 7.3 8.6 0.7 9.1 0.0 0.0 1.1 0.5 1.6 0.5 2.7 0.8 1.2 0.3 0.5 2.9 0.8 0.1 0.2 10.4 0.9 1.7 0.9 9.8 0.7 3.0 2.9 1.9 0.3 1.7 1.9 2.8 1.5 4.6 0.1 0.9 3.1 15.1 1.0 0.5 0.5 3.0 1.0 2.0 2.0 17.0 14.9 1.8 0.6 3.5 2.9 2.4 2.3 0.9 2.8 0.0 2.2 0.0 0.3 2.0 0.2 0.1 0.3 0.1 3.3 0.2 0.3 0.4 0.3 0.0 0.4 2.1 0.3 1.2 6.5 6.1 6.3 7.9 6.2 8.0 7.8 8.3 6.7 6.6 7.6 7.5 0.6 0.0 0.6 2.9 1.1 0.4 0.2 0.0 1.2 3.3 0.1 0.3 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.9 0.1 0.0 0.1 0.3 1.8 2.4 0.4 0.5 0.2 0.0 0.3 5.6 0.1 0.0 0.5 0.0 0.0 0.3 0.0 0.8 1.3 0.0 0.6 0.9 0.0 0.3 1.0 0.0 1.0 0.6 0.6 0.0 1.5 0.0 0.1 0.0 0.0 2.5 0.2 1.3 0.3 0.1 0.6 0.0 0.5 0.8 0.3 0.0 0.3 1.1 0.1 1.6 0.3 0.0 0.2 RBFOX2 "FOX-2, HNRBP2, HRNBP2, RBM9" ENSG00000100320 "RNA binding fox-1 homolog 2" O43251 22 35738736-36028824 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 378.7;Inhibitory neurons: 418.1;Oligodendrocyte precursor cells: 237.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006240, HPA006455, HPA075862" Approved Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA006240: AB_1079750, HPA006455: , HPA075862: " "unprognostic (3.17e-1)" "unprognostic (4.80e-2)" "unprognostic (9.30e-2)" "unprognostic (3.21e-3)" "unprognostic (3.42e-1)" "unprognostic (2.74e-2)" "unprognostic (2.28e-1)" "unprognostic (2.14e-1)" "unprognostic (1.42e-2)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-1)" "unprognostic (1.02e-1)" "unprognostic (5.78e-3)" "unprognostic (2.13e-2)" "unprognostic (1.53e-2)" "unprognostic (6.08e-2)" 28.4 21.9 16.4 12.3 21.7 0.2 27.0 38.8 41.9 49.0 0.0 59.2 11.7 67.5 21.6 34.7 40.4 25.2 37.0 24.3 11.7 18.7 25.8 25.6 5.9 6.9 3.3 63.0 18.7 26.2 27.5 32.6 5.2 31.4 21.4 15.5 23.7 29.7 77.1 23.7 23.4 52.7 1.1 9.9 28.9 25.7 7.3 10.0 28.5 44.3 8.5 43.1 36.5 17.8 46.2 27.4 110.3 64.8 62.4 111.2 36.8 89.9 123.6 67.1 72.0 60.1 21.3 28.2 41.2 108.9 41.9 46.5 40.2 41.7 95.9 19.2 36.6 16.7 26.5 22.3 18.8 4.4 11.6 77.3 53.1 59.6 73.3 64.8 86.8 7.0 13.7 3.9 80.3 14.0 4.5 2.7 40.5 19.7 42.0 7.6 92.0 7.9 50.1 47.5 34.1 106.0 110.3 15.5 31.0 57.0 16.9 6.8 105.5 96.4 54.4 54.7 41.2 2.8 9.4 38.3 42.7 6.8 51.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 16.4 21.7 38.8 41.9 24.3 11.7 6.9 3.3 5.2 1.1 7.3 17.8 34.3 67.3 38.5 189.4 1.0 37.1 50.6 57.3 57.5 20.8 31.4 34.5 62.2 31.5 40.4 27.6 0.0 69.9 0.9 17.9 35.2 53.0 24.8 17.8 60.8 45.9 57.0 0.8 378.7 32.1 89.1 67.8 15.8 25.0 2.5 30.6 40.7 26.0 10.5 117.8 418.1 24.7 18.3 1.3 14.7 9.4 79.6 1.8 16.0 183.6 2.6 16.9 0.0 237.2 130.0 77.4 10.7 93.3 1.4 57.4 22.5 18.7 20.9 6.7 52.6 74.5 93.3 42.2 25.6 31.0 33.8 29.0 2.5 48.2 23.8 61.1 RBMS2 SCR3 ENSG00000076067 "RNA binding motif single stranded interacting protein 2" Q15434 12 56521820-56596193 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039225, HPA058784" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA039225: AB_10963056, HPA058784: AB_2683819" "unprognostic (1.35e-1)" "unprognostic (5.31e-2)" "unprognostic (2.61e-1)" "unprognostic (5.29e-2)" "unprognostic (9.09e-2)" "unprognostic (3.19e-3)" "unprognostic (4.78e-2)" "unprognostic (1.89e-2)" "unprognostic (7.01e-2)" "unprognostic (2.80e-1)" "unprognostic (2.86e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.22e-4)" "unprognostic (2.67e-2)" "unprognostic (4.73e-2)" "unprognostic (4.06e-3)" "unprognostic (2.63e-2)" 19.4 7.1 12.5 5.7 11.5 3.6 17.4 9.3 13.1 14.7 15.1 12.9 4.7 13.7 9.3 8.2 13.7 9.5 15.6 9.2 10.0 14.7 3.4 37.3 3.2 14.5 11.7 12.6 7.0 8.6 6.1 23.5 13.4 11.2 8.8 6.0 10.1 8.7 8.4 8.3 9.0 12.1 9.8 10.5 8.5 4.3 15.2 3.5 18.3 10.8 3.9 10.3 13.9 11.7 28.8 24.3 10.5 14.9 23.7 22.7 9.3 34.8 37.0 26.9 23.9 18.7 50.2 0.2 42.1 36.6 11.1 20.4 7.8 57.8 30.1 8.3 6.7 3.7 19.0 4.8 15.4 3.8 6.5 20.9 13.9 28.1 33.5 31.4 51.1 6.1 1.8 6.5 47.0 3.7 4.1 4.9 6.2 0.0 7.5 2.4 11.5 0.3 34.1 6.4 0.8 6.9 39.6 14.9 5.1 22.2 16.0 6.3 78.2 16.7 35.8 9.5 8.4 6.1 2.5 1.7 6.1 0.9 23.6 0.6 4.7 1.6 0.8 1.3 0.9 0.3 0.3 1.2 2.7 0.5 0.9 0.6 1.6 1.0 0.3 0.6 0.5 0.8 12.5 11.5 9.3 13.1 9.2 10.0 14.5 11.7 13.4 9.8 15.2 11.7 74.4 41.7 20.5 34.6 1.5 3.7 9.7 6.8 11.4 4.2 11.4 9.4 7.9 12.8 14.2 12.9 10.4 19.8 7.0 19.7 1.9 23.6 12.6 16.4 16.9 47.9 5.4 3.2 7.2 16.9 38.5 16.9 6.1 21.8 8.2 10.4 52.1 1.0 10.5 8.4 10.0 5.9 4.1 22.7 5.5 24.2 17.4 11.2 0.0 53.4 6.2 5.4 4.1 30.7 9.6 37.8 11.5 24.8 0.8 13.4 1.6 13.4 6.8 1.7 26.3 11.2 15.5 0.9 1.8 5.4 2.0 23.7 2.5 8.7 7.0 17.3 RDX DFNB24 ENSG00000137710 Radixin P35241 11 109864295-110296712 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin capping, Actin-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 155.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, HPA000763, CAB037312" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 38000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Nucleoplasm "CAB037312: AB_261933, HPA000263: AB_1856043, HPA000763: AB_1856042" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (3.85e-1)" "unprognostic (2.74e-2)" "unprognostic (6.93e-2)" "unprognostic (9.82e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (3.91e-2)" "unprognostic (6.91e-2)" "unprognostic (1.32e-3)" "unprognostic (6.47e-2)" "unprognostic (4.14e-3)" "unprognostic (5.43e-2)" "unprognostic (4.40e-1)" "unprognostic (1.24e-1)" "unprognostic (1.08e-3)" 40.3 155.0 38.0 17.4 57.7 12.0 16.4 50.0 42.7 32.1 32.8 15.2 6.8 28.8 12.9 27.4 19.7 27.2 41.0 35.1 44.7 50.2 68.5 48.8 11.4 52.7 48.2 52.8 52.7 33.2 7.6 35.3 54.3 25.4 11.1 19.2 20.8 26.0 82.1 11.9 7.4 35.0 45.1 26.6 15.0 33.7 47.7 14.3 45.7 59.7 14.6 27.1 10.1 77.6 69.6 35.3 137.3 54.8 78.8 87.4 79.3 85.8 47.6 54.3 59.2 99.7 115.4 0.1 127.4 104.7 84.9 61.5 77.3 80.4 80.5 41.9 44.2 51.5 107.7 74.1 73.6 19.0 33.2 89.7 45.6 68.0 120.1 89.3 149.8 11.1 73.5 29.5 127.0 120.0 11.0 15.6 44.0 4.0 58.4 31.2 96.8 30.1 68.1 33.5 37.2 40.5 148.5 65.9 52.7 102.5 85.0 29.9 92.6 89.5 66.8 43.9 67.4 9.5 17.3 65.9 34.2 11.3 210.9 29.5 14.8 22.0 11.6 12.5 15.5 11.5 10.2 8.8 12.8 8.3 6.8 5.8 2.0 17.6 9.9 10.3 22.0 8.4 38.0 57.7 50.0 42.7 35.1 44.7 52.7 48.2 54.3 45.1 47.7 77.6 248.8 484.0 98.8 53.5 30.0 56.1 51.8 124.6 56.9 85.9 47.4 45.7 159.3 70.1 77.9 75.4 43.8 122.1 21.6 17.7 109.5 128.1 15.5 109.1 117.2 289.2 22.2 104.8 27.1 423.4 189.8 88.4 19.9 135.3 67.2 132.0 319.2 260.1 85.1 101.0 57.6 7.3 61.1 103.2 59.9 43.6 275.2 71.6 72.9 42.2 135.4 77.0 36.0 68.3 229.4 134.3 22.1 266.7 36.1 65.9 0.1 236.9 52.2 94.8 124.9 74.0 143.8 73.9 257.4 52.8 40.5 227.3 29.2 229.9 11.8 45.9 RELCH "FLJ33841, HsT3308, HsT885, KIAA1468" ENSG00000134444 "RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing" Q9P260 18 62187255-62310249 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 7.0;Cardiomyocytes: 9.4;Cytotrophoblasts: 6.5;dendritic cells: 8.2;Extravillous trophoblasts: 4.4;Hofbauer cells: 7.2;Plasma cells: 5.2;Syncytiotrophoblasts: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039708, HPA040038" Approved Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Centriolar satellite, Cytosol" "HPA039708: AB_10794753, HPA040038: AB_10793860" "unprognostic (1.33e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (4.03e-2)" "unprognostic (1.98e-3)" "unprognostic (2.44e-2)" "unprognostic (6.30e-2)" "unprognostic (3.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.36e-1)" "unprognostic (4.84e-3)" "unprognostic (2.47e-2)" "unprognostic (6.86e-2)" "unprognostic (3.54e-1)" "unprognostic (1.71e-2)" 8.3 8.8 8.7 9.6 10.8 14.2 11.9 11.1 10.0 11.8 7.2 11.5 9.5 8.5 11.8 25.4 7.7 7.9 7.5 9.7 9.3 9.6 7.9 8.0 11.8 7.9 7.6 8.2 8.3 10.3 11.0 8.1 8.2 12.1 14.4 16.3 12.5 8.8 6.8 20.6 10.8 6.2 7.6 11.2 12.7 5.3 8.8 10.8 9.5 5.9 13.2 10.0 16.2 9.4 9.7 8.7 10.4 10.0 10.8 12.7 11.1 17.0 14.1 15.0 16.5 4.5 8.8 6.6 8.6 15.1 9.8 19.7 14.9 10.2 18.3 6.0 9.3 5.6 9.7 10.4 9.6 10.8 7.4 9.4 12.3 12.8 7.8 12.3 10.3 6.2 4.2 6.5 15.9 5.7 6.7 9.3 6.0 6.5 7.3 8.2 13.0 7.9 17.1 19.1 14.7 7.8 10.2 14.9 8.9 13.4 7.7 11.6 12.9 15.9 5.0 6.9 8.6 19.0 3.7 6.4 11.2 11.4 13.0 1.4 1.0 1.2 1.1 0.8 0.8 0.8 1.0 1.0 1.0 0.9 1.1 1.3 1.7 1.1 0.7 0.7 1.3 0.6 8.7 10.8 11.1 10.0 9.7 9.3 7.9 7.6 8.2 7.6 8.8 9.4 7.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 6.5 8.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 4.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 6.6 1.1 0.0 0.0 0.0 RGCC "bA157L14.2, C13orf15, RGC-32, RGC32" ENSG00000102760 "Regulator of cell cycle" Q9H4X1 13 41457550-41470871 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 415.4;lung: 694.9" "Cell type enhanced" "Detected in many" "Adipocytes: 1286.2;Basal prostatic cells: 676.2;Langerhans cells: 590.1;Prostatic glandular cells: 1415.5;T-cells: 532.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 159.9;T-reg: 90.9" "Lineage enriched" "Detected in many" 15 "T-cells: 159.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 57.5;BJ hTERT+: 316.0;Daudi: 105.1;U-698: 111.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035638, HPA063701" Enhanced Supported Nucleoplasm,Nucleoli "Intracellular and membrane" No No 910000 "Cluster 20: T-cells - T-cell receptor" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Nucleoli "HPA035638: AB_10670152, HPA063701: AB_2685096" "unprognostic (1.39e-3)" "unprognostic (4.61e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (2.28e-1)" "unprognostic (4.27e-2)" "unprognostic (2.85e-1)" "unprognostic (1.49e-3)" "unprognostic (1.49e-2)" "unprognostic (3.99e-2)" "unprognostic (1.57e-3)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.81e-2)" "unprognostic (3.04e-3)" "unprognostic (1.48e-1)" "unprognostic (2.30e-1)" "unprognostic (1.42e-3)" 197.6 21.5 186.3 27.7 226.9 415.4 132.6 218.8 236.7 36.1 148.2 34.7 16.9 43.6 7.6 18.6 31.1 42.2 145.9 195.8 196.6 56.9 25.0 694.9 38.1 209.1 204.8 9.1 41.3 48.1 35.3 150.7 205.3 61.5 9.2 5.7 111.5 19.0 47.3 58.0 29.1 33.5 186.7 37.0 37.8 24.8 198.2 70.5 144.0 61.8 21.0 47.5 39.6 241.0 1.1 0.5 34.9 0.0 6.7 57.5 1.4 0.8 316.0 0.2 1.2 44.8 0.7 105.1 0.9 4.0 0.1 1.0 1.2 2.1 0.4 11.1 5.1 0.0 7.9 3.5 3.3 3.7 1.2 4.5 6.7 1.2 43.1 0.6 36.1 24.0 8.3 0.1 1.0 0.3 24.0 2.3 0.5 4.7 0.8 0.1 0.0 0.1 0.3 0.0 1.3 0.4 0.3 0.0 0.7 3.0 0.9 20.1 24.6 0.2 3.8 2.2 0.4 0.2 0.1 111.9 0.3 2.4 0.8 0.0 0.8 0.1 5.6 0.5 5.6 5.3 46.5 14.7 6.1 10.7 159.9 35.0 0.6 0.4 0.1 1.8 90.9 10.2 186.3 226.9 218.8 236.7 195.8 196.6 209.1 204.8 205.3 186.7 198.2 241.0 1286.2 246.8 39.8 57.5 131.8 86.5 676.2 15.2 14.2 1.0 269.9 314.7 25.8 1.5 37.5 3.7 2.1 6.4 249.2 3.0 35.2 0.6 42.3 103.0 47.2 474.6 84.8 322.7 2.5 0.0 9.3 205.1 65.2 69.0 48.9 0.3 31.8 2.5 349.1 0.0 1.2 22.1 14.2 32.0 590.1 13.2 8.1 315.9 193.9 36.5 6.4 1.5 4.1 51.8 115.3 0.3 4.5 2.2 371.2 1415.5 0.1 0.8 33.7 3.1 124.9 45.4 116.0 155.3 5.0 11.2 65.1 11.1 532.4 43.8 7.8 159.7 RGMB "DRAGON, FLJ90406" ENSG00000174136 "Repulsive guidance molecule BMP co-receptor b" Q6NW40 5 98768650-98798643 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 63.9;Undifferentiated cells: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 3.3" "Group enriched" "Detected in many" 12 "B-cells: 1.6;T-cells: 3.3" "Cell line enhanced" "Detected in many" "BJ: 285.8;BJ hTERT+: 142.9;fHDF/TERT166: 178.0;HBF TERT88: 222.5;LHCN-M2: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016993 Approved Nucleoplasm NA NA 560000 "Cluster 32: T-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA016993: AB_1856216" "unprognostic (1.50e-2)" "unprognostic (3.77e-2)" "unprognostic (9.03e-2)" "unprognostic (8.92e-2)" "unprognostic (2.88e-1)" "unprognostic (5.27e-2)" "unprognostic (7.44e-2)" "unprognostic (1.60e-2)" "unprognostic (8.24e-2)" "unprognostic (2.19e-1)" "unprognostic (3.60e-3)" "unprognostic (9.00e-2)" "unprognostic (3.88e-2)" "unprognostic (3.90e-2)" "unprognostic (6.40e-2)" "unprognostic (4.20e-2)" "unprognostic (3.78e-3)" 8.8 7.7 14.8 7.2 18.4 0.3 9.1 11.4 17.4 9.3 5.7 20.5 21.4 9.2 6.0 11.8 11.1 7.5 10.2 17.4 15.1 4.7 6.0 8.1 3.7 12.9 16.0 21.8 11.2 9.3 11.4 5.5 27.1 20.7 33.3 3.8 21.8 13.9 24.8 33.8 26.2 10.9 12.2 6.0 41.7 10.5 22.3 2.6 11.5 16.1 4.5 10.8 9.5 14.9 7.3 5.2 87.8 8.1 26.2 44.5 9.1 285.8 142.9 138.5 97.6 4.4 3.5 4.2 10.2 178.0 9.7 7.5 10.4 26.0 222.5 12.5 10.2 0.0 7.1 4.9 12.6 0.9 0.1 37.1 9.4 71.1 28.2 37.6 26.3 13.6 0.0 3.5 167.1 8.1 0.1 0.1 6.0 3.3 14.0 11.4 50.7 7.9 5.4 8.4 35.6 18.0 3.9 9.4 14.1 4.4 7.5 0.4 57.4 86.7 14.2 54.1 133.5 6.0 9.1 5.8 31.9 0.1 19.1 0.0 0.0 0.2 0.1 0.0 0.7 1.1 1.5 0.6 0.0 1.6 3.3 1.5 0.1 0.1 0.0 0.0 2.4 0.8 14.8 18.4 11.4 17.4 17.4 15.1 12.9 16.0 27.1 12.2 22.3 14.9 8.6 16.0 4.1 7.5 12.7 31.0 15.3 6.0 44.3 5.7 17.8 12.4 14.3 7.2 5.3 9.2 16.7 4.5 0.4 12.8 1.9 5.0 63.9 10.2 12.7 10.3 21.8 0.0 20.8 5.3 6.2 19.1 18.8 18.0 0.0 4.0 9.3 8.2 2.1 0.0 23.6 44.6 4.1 1.0 7.2 16.9 9.0 2.4 12.4 5.6 0.7 1.7 0.0 35.2 6.6 8.4 16.3 7.2 1.7 16.1 11.9 1.6 6.1 4.0 0.0 20.3 13.1 7.4 17.5 27.0 24.4 1.8 2.9 5.4 88.9 17.4 RGS7 ENSG00000182901 "Regulator of G protein signaling 7" P49802 1 240775514-241357230 "Plasma proteins, Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.0;brain: 28.1;retina: 12.8" "Cell type enhanced" "Detected in some" "Astrocytes: 288.3;Excitatory neurons: 1353.2;Inhibitory neurons: 1095.0;Oligodendrocyte precursor cells: 615.8" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 6.2;HaCaT: 5.3;hTERT-HME1: 7.2;RH-30: 6.4;SH-SY5Y: 5.6;U-2 OS: 5.9;U-251 MG: 7.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017561 Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 6: Brain - Smell perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Mitochondria "CAB017561: AB_2285043" "unprognostic (6.48e-2)" "unprognostic (4.30e-2)" "unprognostic (4.67e-2)" "unprognostic (6.65e-2)" "unprognostic (7.84e-3)" "unprognostic (4.09e-2)" "unprognostic (1.49e-2)" "unprognostic (3.61e-1)" "unprognostic (1.42e-2)" "unprognostic (2.51e-4)" "unprognostic (3.54e-1)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.64e-2)" "unprognostic (2.28e-1)" 0.0 8.0 11.6 0.0 13.5 0.0 0.1 18.9 28.1 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.4 0.0 15.9 8.6 2.4 0.4 0.1 0.3 2.5 3.8 0.4 0.5 0.2 2.8 0.0 6.8 0.1 0.1 12.8 0.0 0.5 0.0 0.1 0.1 0.0 2.6 0.2 2.9 5.3 6.4 0.0 0.0 0.0 0.2 0.0 0.0 13.9 0.9 0.0 0.0 0.0 0.2 0.7 0.0 2.5 4.8 6.2 0.4 0.0 0.0 0.0 0.3 3.3 3.4 5.3 0.0 0.0 3.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.2 0.5 0.4 0.0 0.0 0.0 1.9 0.0 0.0 0.0 3.3 0.3 0.2 0.0 6.4 0.0 0.0 0.0 5.3 5.6 0.3 0.2 0.2 0.2 0.0 0.0 2.6 0.0 5.9 0.3 7.2 0.0 4.1 0.0 0.9 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 11.6 13.5 18.9 28.1 15.9 8.6 2.5 3.8 6.8 2.6 6.4 13.9 0.0 0.0 0.0 288.3 2.8 0.0 0.1 0.0 0.0 29.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.1 2.3 0.0 3.5 0.2 7.2 0.0 1353.2 0.0 0.0 0.5 1.5 0.1 0.0 10.0 0.4 0.4 0.1 62.2 1095.0 0.4 0.0 0.0 0.3 4.1 0.0 0.1 0.0 29.0 0.0 1.0 0.0 615.8 86.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.7 6.3 10.8 0.0 0.0 0.0 0.0 0.1 0.1 0.1 RHOA "ARH12, ARHA, Rho12, RHOH12" ENSG00000067560 "Ras homolog family member A" P61586 3 49359139-49412998 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Host-virus interaction" Hydrolase "Cancer-related genes, Disease variant, Ectodermal dysplasia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005052 Approved Supported "Plasma membrane,Cytosol" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB005052: AB_562216" "unprognostic (1.50e-1)" "unprognostic (3.38e-1)" "prognostic favorable (3.08e-4)" "unprognostic (8.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.39e-1)" "unprognostic (8.83e-2)" "unprognostic (9.44e-3)" "unprognostic (2.21e-2)" "unprognostic (4.29e-2)" "prognostic favorable (3.21e-6)" "unprognostic (5.14e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (4.52e-2)" 452.4 315.0 234.6 357.9 258.6 473.4 360.0 257.1 274.1 310.4 237.4 351.9 274.6 293.8 298.6 362.6 269.2 267.1 269.6 220.8 271.2 286.9 274.5 430.9 396.3 282.9 245.8 297.2 225.3 269.4 164.3 396.8 287.2 244.5 369.3 113.3 238.0 315.6 331.0 281.3 281.0 416.9 259.3 329.1 292.1 154.1 257.5 387.7 326.3 298.5 454.9 358.2 273.6 292.5 470.4 406.1 500.9 512.7 569.9 858.9 370.8 930.1 735.7 790.3 722.4 347.6 527.4 721.8 251.6 1404.1 448.8 259.5 560.4 630.6 817.6 505.7 323.3 678.8 488.0 416.0 604.2 647.9 472.8 668.2 437.8 643.2 508.1 799.7 1038.0 391.9 361.1 437.9 967.5 254.3 717.3 739.0 441.4 548.2 497.1 325.5 451.4 610.5 701.9 559.6 167.7 387.3 599.0 464.5 495.4 499.4 301.7 819.6 972.1 558.4 483.2 737.2 725.7 388.0 775.6 754.8 567.9 691.6 678.3 716.9 1105.5 1160.5 480.1 1358.8 423.8 432.7 415.6 479.6 806.9 379.3 314.5 397.1 1282.7 440.9 1398.1 645.5 554.9 1884.8 234.6 258.6 257.1 274.1 220.8 271.2 282.9 245.8 287.2 259.3 257.5 292.5 502.8 387.8 265.2 20.5 374.6 270.9 260.0 236.1 251.6 47.1 239.4 223.1 141.1 178.7 220.9 180.3 6.2 355.8 373.1 447.2 340.4 339.5 48.2 174.2 243.7 413.8 234.4 319.3 26.1 347.8 709.8 386.2 313.9 201.0 257.3 141.6 312.7 173.2 760.0 82.4 27.0 344.9 191.2 771.9 495.8 55.6 335.2 683.7 327.3 52.5 710.0 219.9 389.3 24.6 51.4 398.0 354.6 407.7 375.7 334.1 341.3 350.8 201.1 40.8 276.1 354.1 450.1 264.4 253.6 390.8 279.6 525.2 359.5 299.1 347.7 371.4 RIC8A "synembryn, synembryn-A" ENSG00000177963 "RIC8 guanine nucleotide exchange factor A" Q9NPQ8 11 207511-215113 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041491, CAB046012" Approved Approved "Plasma membrane,Cytosol" NA NA 10000 "Cluster 44: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Plasma membrane" "CAB046012: AB_11129402, HPA041491: AB_2677510" "unprognostic (3.93e-2)" "unprognostic (8.69e-2)" "unprognostic (1.62e-1)" "prognostic favorable (8.60e-4)" "unprognostic (1.61e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.11e-6)" "unprognostic (2.13e-3)" "unprognostic (8.70e-2)" "unprognostic (7.68e-2)" "unprognostic (1.56e-1)" "unprognostic (8.35e-2)" "unprognostic (2.63e-3)" "unprognostic (5.35e-2)" "unprognostic (2.57e-1)" "unprognostic (2.14e-1)" "unprognostic (1.60e-1)" 39.2 39.6 43.0 34.8 43.6 40.6 37.4 42.1 48.5 41.2 46.6 46.3 29.5 44.2 41.8 43.1 41.1 30.6 42.9 45.4 43.7 36.5 37.8 37.6 37.6 43.5 44.4 39.7 39.3 34.2 38.1 34.1 44.2 39.0 30.8 24.8 34.4 40.3 32.8 39.5 38.1 49.4 43.4 41.6 38.1 44.0 44.0 41.6 33.7 28.3 41.8 45.9 36.6 45.0 176.3 83.9 66.8 66.7 89.7 73.4 46.3 124.1 99.2 166.0 114.2 72.6 121.1 69.6 50.5 189.0 125.7 93.4 76.4 131.4 92.0 84.5 76.7 39.4 59.5 67.8 72.3 66.5 125.8 80.6 114.3 103.2 92.6 85.2 82.8 72.8 68.7 66.0 129.3 71.1 79.6 52.6 61.1 74.0 103.0 74.0 66.0 47.5 96.9 45.6 69.2 62.2 96.3 107.1 67.1 63.9 76.1 52.8 93.4 109.2 96.5 40.4 117.3 72.6 117.6 67.8 107.7 59.5 83.5 72.9 41.1 88.3 79.0 49.7 78.2 64.4 70.1 69.0 43.7 55.1 59.9 60.6 59.9 73.0 61.0 35.8 65.0 86.6 43.0 43.6 42.1 48.5 45.4 43.7 43.5 44.4 44.2 43.4 44.0 45.0 30.9 16.0 21.1 10.7 28.7 17.7 20.5 38.6 17.1 28.1 22.5 27.2 23.5 28.6 25.5 25.8 10.4 41.4 46.5 26.3 27.4 53.1 20.2 15.9 24.3 27.2 20.3 27.4 9.4 44.2 60.0 30.4 23.0 19.7 17.7 28.8 27.8 17.1 46.8 32.0 8.4 19.2 30.5 27.4 11.5 17.3 30.7 27.5 28.4 11.2 38.9 43.4 30.9 5.0 7.8 71.6 25.5 39.9 35.2 26.5 29.9 23.0 20.8 33.1 19.7 20.7 35.4 93.2 62.5 20.9 19.5 32.4 34.8 30.2 25.0 17.0 RIPOR1 "FAM65A, FLJ13725" ENSG00000039523 "RHO family interacting cell polarization regulator 1" Q6ZS17 16 67518418-67546788 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 49.2;Endothelial cells: 23.6;Hofbauer cells: 30.0;Pancreatic endocrine cells: 37.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 11.2;eosinophil: 9.3;intermediate monocyte: 15.6;memory B-cell: 15.8;myeloid DC: 10.2;naive B-cell: 9.4;neutrophil: 6.6;non-classical monocyte: 15.1;plasmacytoid DC: 14.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005923 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus, Cytosol" "HPA005923: AB_1078809" "unprognostic (7.41e-2)" "unprognostic (2.07e-2)" "unprognostic (1.56e-3)" "unprognostic (3.71e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.10e-2)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.38e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.82e-8)" "unprognostic (8.51e-2)" "unprognostic (3.52e-2)" "unprognostic (1.19e-1)" "unprognostic (7.46e-2)" 44.4 28.1 27.6 23.4 30.6 27.2 37.7 26.4 38.6 39.9 7.5 36.0 8.8 45.2 6.0 18.5 36.2 21.5 53.6 33.6 16.3 67.6 16.7 55.8 20.8 26.6 17.1 33.2 30.1 20.6 26.5 29.8 25.4 30.6 7.4 43.8 22.8 20.2 34.9 21.4 32.7 25.2 12.3 61.2 25.9 18.6 21.5 10.8 36.4 22.3 17.5 37.1 30.4 18.6 44.0 36.6 16.1 25.3 40.0 35.7 35.7 45.7 44.9 51.6 43.0 75.7 31.5 6.0 62.4 78.8 26.0 24.4 32.7 41.3 33.2 19.3 17.0 57.9 53.6 17.4 44.7 4.6 28.0 35.5 18.8 69.7 47.1 36.8 55.2 10.2 6.5 6.4 38.7 47.7 13.8 14.4 4.4 8.5 29.1 46.8 29.0 31.2 39.0 22.1 12.1 31.9 85.1 13.8 28.6 15.9 30.2 10.7 96.8 58.3 34.2 49.8 32.2 9.0 6.8 17.8 38.8 11.1 31.7 0.1 11.2 9.3 1.2 15.6 1.8 15.8 1.0 0.5 10.2 9.4 0.7 0.7 6.6 1.7 15.1 14.4 0.8 6.0 27.6 30.6 26.4 38.6 33.6 16.3 26.6 17.1 25.4 12.3 21.5 18.6 49.2 16.0 16.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 12.1 8.8 0.0 0.0 1.8 7.3 0.0 0.8 3.7 0.0 0.0 15.8 0.0 9.3 17.9 23.6 0.0 0.0 0.0 12.5 1.3 6.9 0.0 18.5 10.1 7.9 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 37.0 0.0 0.0 2.3 0.0 0.0 5.8 2.2 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 2.1 2.3 16.6 0.0 0.0 RND3 "ARHE, Rho8, RhoE" ENSG00000115963 "Rho family GTPase 3" P61587 2 150468195-150539011 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 155.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1633.3;Endometrial stromal cells: 521.7;Suprabasal keratinocytes: 924.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 680.9;BJ hTERT+: 1331.5;hTERT-HME1: 650.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060504 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA060504: AB_2684295" "unprognostic (8.03e-2)" "unprognostic (3.04e-2)" "unprognostic (2.36e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-2)" "unprognostic (4.69e-2)" "unprognostic (1.64e-1)" "unprognostic (2.70e-3)" "unprognostic (4.23e-2)" "unprognostic (6.59e-2)" "unprognostic (1.27e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (1.78e-4)" "unprognostic (1.47e-1)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (2.03e-2)" 58.0 50.0 12.1 27.8 8.6 1.2 99.2 8.6 9.2 47.8 8.1 27.2 16.8 45.2 7.3 155.4 14.0 59.9 23.6 8.8 10.2 14.6 131.9 23.2 11.4 8.5 8.4 8.4 16.2 1.9 7.8 46.4 18.4 46.0 27.1 5.2 28.9 37.7 14.4 50.5 19.9 62.3 7.1 39.5 20.2 4.7 14.2 8.2 7.4 14.0 24.5 108.8 44.1 7.0 46.5 27.5 49.2 93.8 137.1 65.7 0.4 680.9 1331.5 335.0 189.1 34.8 31.4 0.0 42.5 277.8 173.1 108.2 1.9 43.9 268.5 0.0 20.4 0.0 35.1 1.1 391.2 0.1 0.5 46.2 78.6 344.9 650.7 62.9 65.4 0.4 0.0 158.2 145.0 27.5 0.3 0.3 15.4 47.5 42.3 0.1 37.7 21.5 74.5 80.7 15.0 46.4 71.5 29.3 37.2 35.9 33.3 1.1 67.4 296.3 55.3 137.8 73.8 35.7 0.4 0.4 234.2 0.1 209.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 8.6 8.6 9.2 8.8 10.2 8.5 8.4 18.4 7.1 14.2 7.0 81.3 38.5 5.8 2.0 0.4 1633.3 231.2 304.7 368.2 40.5 131.9 218.1 95.6 45.8 192.5 9.2 14.6 71.7 1.8 359.8 3.9 63.4 1.9 389.9 521.7 46.3 32.8 5.3 0.6 14.6 12.8 353.4 56.6 400.3 4.5 0.6 26.4 129.3 12.2 1.7 35.3 130.5 97.6 76.8 83.0 2.2 10.5 12.0 136.9 15.0 0.0 9.6 0.0 0.5 0.5 107.4 249.5 10.5 4.6 102.4 174.8 3.9 157.0 2.7 19.7 182.0 166.8 0.9 3.4 458.0 924.7 91.1 10.9 36.8 117.5 262.9 RPN1 OST1 ENSG00000163902 "Ribophorin I" P04843 3 128619969-128681075 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 424.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009748, HPA026828, HPA051520" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA 730000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" Cytosol "CAB009748: AB_2182230, HPA026828: AB_10610418, HPA051520: AB_2681521" "unprognostic (4.83e-2)" "unprognostic (5.92e-2)" "unprognostic (1.10e-1)" "unprognostic (7.67e-2)" "unprognostic (2.36e-1)" "unprognostic (2.12e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.71e-1)" "unprognostic (2.43e-1)" "unprognostic (2.28e-2)" "unprognostic (4.58e-3)" "unprognostic (2.87e-1)" "unprognostic (7.68e-2)" "unprognostic (7.86e-2)" "unprognostic (1.52e-2)" "unprognostic (1.44e-1)" "unprognostic (9.74e-2)" 97.9 88.3 56.7 94.5 65.5 97.1 105.5 69.0 63.3 142.0 96.2 124.0 97.1 92.0 352.4 76.6 124.8 90.5 82.6 56.1 71.4 119.5 226.3 112.7 76.8 72.7 65.8 80.8 118.8 143.8 83.7 139.8 69.4 100.2 134.3 46.9 120.4 113.9 89.2 63.5 94.5 111.6 66.7 85.2 115.0 90.9 68.1 86.0 177.7 77.7 102.4 117.2 64.0 77.9 358.5 190.9 156.2 289.8 412.7 273.1 351.3 300.0 393.2 391.4 452.1 399.4 328.2 221.9 274.8 437.3 363.2 349.7 255.4 268.2 374.7 158.8 160.3 392.7 127.9 332.3 454.3 322.5 198.2 229.5 307.3 258.4 377.5 260.9 308.6 164.2 164.2 289.6 260.4 327.8 179.7 353.0 198.1 476.6 170.2 193.6 209.4 540.6 272.7 212.0 238.6 137.4 246.3 253.6 313.6 199.0 271.0 329.0 203.2 200.9 154.7 297.0 226.9 306.1 259.9 234.4 329.4 235.9 296.9 178.0 171.6 137.6 129.3 147.0 154.7 91.5 104.7 117.7 159.5 60.7 63.8 99.3 233.2 90.3 159.3 192.4 114.2 250.8 56.7 65.5 69.0 63.3 56.1 71.4 72.7 65.8 69.4 66.7 68.1 77.9 82.9 60.9 74.1 13.1 72.4 49.5 83.6 102.8 55.2 13.0 53.7 26.9 42.4 51.5 91.6 112.2 8.4 113.7 59.1 126.0 15.6 111.5 19.1 85.3 73.9 72.4 43.3 63.5 11.7 93.3 199.1 91.7 113.2 126.8 43.7 40.2 96.0 180.0 135.7 20.2 16.3 158.4 73.2 154.1 70.8 29.5 94.1 87.6 58.7 11.2 77.0 30.3 39.1 18.1 21.3 104.0 83.1 64.3 424.1 93.3 109.1 90.7 110.2 13.2 46.0 43.9 53.7 65.9 62.6 67.0 53.4 156.7 65.8 54.0 130.2 78.9 RTN4 "ASY, KIAA0886, NOGO, NSP-CL" ENSG00000115310 "Reticulon 4" Q9NQC3 2 54972187-55112621 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 3547.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 95.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1801.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005388, HPA023977" Supported Enhanced "Endoplasmic reticulum" NA NA 3400000 "Cluster 38: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "CAB005388: AB_2285559, HPA023977: AB_2671391" "unprognostic (1.31e-2)" "unprognostic (1.71e-3)" "unprognostic (6.76e-2)" "unprognostic (1.28e-3)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.00e-4)" "unprognostic (5.79e-2)" "unprognostic (1.84e-3)" "unprognostic (2.47e-1)" "unprognostic (1.97e-1)" "unprognostic (3.91e-3)" "unprognostic (4.38e-1)" "unprognostic (4.41e-2)" "unprognostic (1.29e-2)" "unprognostic (4.99e-2)" "unprognostic (1.27e-1)" "unprognostic (4.91e-2)" 586.2 302.7 376.3 150.9 461.9 115.4 253.1 465.9 534.3 118.0 297.1 186.9 236.2 153.9 176.5 217.9 130.0 196.8 166.0 411.8 431.6 442.5 551.9 211.8 83.6 498.6 456.5 132.0 122.7 236.7 84.0 177.3 524.8 223.9 179.2 640.6 127.1 183.4 996.0 252.9 292.5 246.4 440.8 110.3 124.0 78.6 453.2 87.1 130.7 777.9 88.2 291.2 147.9 591.2 402.9 285.3 273.3 71.7 908.4 845.0 153.2 1301.6 1097.4 393.5 365.7 235.5 371.7 87.1 673.8 889.9 657.7 355.6 181.5 524.4 596.2 248.3 139.4 120.3 159.6 376.6 1801.9 218.1 59.7 638.5 490.8 540.3 1041.9 792.3 751.3 215.6 249.8 195.0 1724.1 117.8 268.3 222.0 245.9 86.8 252.0 118.5 360.3 180.0 924.0 475.9 179.2 211.3 297.7 173.3 378.1 465.1 147.2 165.1 1074.9 764.8 326.1 304.8 756.5 118.0 103.4 56.1 778.7 247.9 630.1 95.8 9.5 27.5 9.2 11.6 7.6 6.8 14.7 8.2 9.2 3.8 24.1 10.2 15.6 41.1 19.0 13.7 37.6 9.9 376.3 461.9 465.9 534.3 411.8 431.6 498.6 456.5 524.8 440.8 453.2 591.2 451.4 176.3 203.4 201.4 102.3 1062.1 1456.6 367.0 225.9 644.6 297.6 260.6 182.0 243.1 251.0 676.8 379.5 529.6 173.6 408.6 291.6 559.7 459.7 316.6 264.6 308.0 222.1 98.2 454.5 323.4 611.9 421.9 98.4 324.7 150.4 161.5 181.3 633.4 669.1 425.7 370.4 280.5 231.9 339.0 578.4 266.6 167.4 371.7 341.5 215.5 396.4 3547.4 137.0 249.3 1334.3 571.2 309.7 226.1 81.6 921.4 897.1 678.3 233.6 540.0 216.9 420.5 324.6 382.7 90.1 247.1 1059.3 362.0 145.5 100.1 238.1 1226.5 RUSC2 KIAA0375 ENSG00000198853 "RUN and SH3 domain containing 2" Q8N2Y8 9 35490111-35561898 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 33.6;Excitatory neurons: 61.5;Inhibitory neurons: 63.5;Microglial cells: 43.1;Oligodendrocyte precursor cells: 52.3;Oligodendrocytes: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "TIME: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021297 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 47: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA021297: AB_1856510" "unprognostic (4.67e-1)" "unprognostic (1.04e-1)" "unprognostic (1.22e-2)" "unprognostic (1.32e-3)" "unprognostic (3.46e-1)" "unprognostic (2.36e-1)" "unprognostic (1.24e-2)" "unprognostic (6.13e-2)" "unprognostic (3.88e-1)" "unprognostic (1.66e-2)" "unprognostic (1.45e-2)" "unprognostic (6.62e-3)" "unprognostic (2.46e-2)" "unprognostic (4.56e-2)" "unprognostic (2.01e-1)" "unprognostic (2.94e-2)" "unprognostic (9.38e-3)" 21.0 17.9 28.0 5.9 30.6 5.8 16.7 17.9 40.2 22.0 3.0 34.3 5.1 22.1 5.6 12.5 18.7 9.3 25.9 29.7 17.3 17.6 11.9 16.8 2.8 19.5 16.4 18.9 13.0 7.0 21.7 8.0 19.9 18.5 3.9 12.2 12.2 15.3 45.2 12.9 9.3 15.1 11.4 12.1 14.8 22.4 19.7 1.5 18.1 36.1 2.0 32.3 16.1 30.5 12.2 18.4 6.6 6.4 17.6 15.9 7.3 35.5 21.7 16.3 14.4 5.4 4.8 0.0 11.8 29.5 44.3 2.4 6.0 11.1 7.2 0.0 5.2 2.2 30.7 4.2 25.5 0.0 31.3 13.9 5.9 28.4 28.2 26.4 17.5 4.9 5.2 0.1 27.5 3.6 1.1 0.8 5.0 0.1 8.4 7.4 4.6 0.1 10.4 1.3 1.6 11.1 8.3 16.6 6.7 9.2 10.4 4.3 49.3 25.1 17.0 22.3 18.4 0.3 0.6 0.0 24.8 6.9 17.1 3.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 28.0 30.6 17.9 40.2 29.7 17.3 19.5 16.4 19.9 11.4 19.7 30.5 7.7 6.4 4.8 33.6 0.0 2.7 3.6 1.6 4.6 15.2 2.2 3.2 6.1 8.6 2.4 7.3 14.6 0.8 0.2 0.1 1.9 7.8 8.7 1.4 4.4 10.4 0.0 1.3 61.5 6.7 6.1 7.8 1.1 3.2 5.7 3.0 5.3 2.1 2.4 13.5 63.5 0.2 0.0 2.2 3.2 3.5 8.7 2.6 5.4 43.1 0.4 6.9 0.0 52.3 38.7 8.4 0.0 7.5 0.3 4.3 0.4 3.1 3.0 7.5 0.0 5.0 10.0 9.5 2.6 0.8 1.7 0.7 0.4 1.3 0.7 1.4 S100A4 "18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98" ENSG00000196154 "S100 calcium binding protein A4" P26447 1 153543613-153550136 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 2708.8;Langerhans cells: 5952.7;Macrophages: 2786.0;monocytes: 3172.6;NK-cells: 2130.8;Skeletal myocytes: 2034.0;T-cells: 2111.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 2614.3;ASC diff: 3300.1;BJ hTERT+: 6738.6;fHDF/TERT166: 4819.1;RPMI-8226: 2700.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.6" "CAB002618, HPA007486, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 9600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB002618: , CAB027387: , CAB058698: AB_2665603, CAB068227: AB_2665602, CAB068228: AB_2665601, HPA007486: , HPA007973: AB_1079858" "unprognostic (1.56e-1)" "unprognostic (6.10e-2)" "unprognostic (2.84e-2)" "unprognostic (8.20e-2)" "unprognostic (6.21e-2)" "prognostic favorable (4.03e-5)" "unprognostic (8.35e-2)" "unprognostic (4.81e-2)" "unprognostic (1.50e-1)" "unprognostic (2.20e-1)" "unprognostic (2.78e-2)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.05e-1)" "unprognostic (3.05e-1)" "unprognostic (2.76e-2)" "unprognostic (3.16e-2)" 982.3 77.1 25.5 353.9 26.2 1090.8 561.9 27.5 53.1 566.3 32.0 301.7 91.7 177.8 124.5 224.0 217.6 167.6 268.5 24.7 27.4 247.0 64.3 874.2 221.0 31.7 26.4 51.0 53.8 18.1 24.8 182.9 29.8 223.7 331.5 10.0 245.4 155.8 163.0 371.5 234.3 297.7 27.8 443.0 133.3 32.2 33.7 112.6 191.9 424.6 315.4 391.6 455.2 34.1 11.8 2614.3 13.2 77.0 3300.1 2410.9 3.7 1664.4 6738.6 32.1 148.4 20.0 180.3 0.8 299.7 4819.1 3.5 65.3 8.8 20.9 23.6 405.2 2.3 1186.8 529.0 59.4 4.3 106.9 1924.6 364.2 21.5 62.2 13.0 4.9 2.6 0.7 9.9 4.2 2468.1 10.6 3.8 1273.9 7.2 189.7 1050.4 64.1 3.7 2700.2 103.5 71.3 108.5 11.6 24.9 1286.6 9.4 412.5 77.1 1493.7 3.1 8.5 13.7 2159.5 9.3 82.8 647.5 14.3 6.1 1367.9 127.2 2789.7 13536.2 1408.0 5800.5 9099.6 6077.0 761.6 5167.7 4700.0 9268.4 282.5 882.4 2641.3 12129.7 837.1 11862.4 1626.0 7406.7 24075.8 25.5 26.2 27.5 53.1 24.7 27.4 31.7 26.4 29.8 27.8 33.7 34.1 226.0 490.4 398.4 0.0 266.1 772.9 19.5 159.0 93.9 0.7 44.9 65.9 14.9 35.8 273.8 893.8 0.0 52.4 1345.4 8.9 111.6 21.9 7.3 53.0 473.0 209.1 4.8 730.9 0.0 23.5 255.5 1378.8 54.0 41.9 1395.8 0.6 96.4 18.6 1966.1 45.4 0.0 10.0 345.8 2708.8 5952.7 24.0 235.8 2786.0 1193.5 12.2 3172.6 3.6 2130.8 0.0 0.1 35.7 17.0 45.9 266.5 12.9 3.2 19.7 154.9 2.3 151.2 2034.0 1309.6 1.9 5.5 77.6 694.0 53.4 2111.1 32.5 11.3 73.1 SACS "ARSACS, DKFZp686B15167, DNAJC29, KIAA0730, PPP1R138, SPAX6" ENSG00000151835 "Sacsin molecular chaperone" Q9NZJ4 13 23328826-23433740 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 70.5;Excitatory neurons: 86.3;Inhibitory neurons: 108.2;Oligodendrocyte precursor cells: 76.4;Oligodendrocytes: 111.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017714 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB017714: " "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.02e-3)" "prognostic unfavorable (9.04e-4)" "unprognostic (1.26e-2)" "unprognostic (1.66e-1)" "unprognostic (2.05e-3)" "unprognostic (2.59e-2)" "unprognostic (2.49e-1)" "unprognostic (4.14e-2)" "unprognostic (5.05e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.21e-6)" "unprognostic (2.84e-1)" "unprognostic (4.06e-2)" "unprognostic (3.67e-2)" "unprognostic (7.65e-4)" 4.8 4.4 4.7 4.0 10.0 5.6 4.3 7.2 16.1 4.8 0.0 8.0 0.9 6.2 2.7 3.7 5.8 2.2 8.7 7.6 3.0 3.2 2.2 4.8 4.3 8.4 5.2 4.7 4.8 15.2 6.8 1.3 9.4 7.6 1.5 4.6 6.6 2.3 14.0 2.4 5.0 4.9 2.0 8.5 5.1 6.8 10.3 4.2 2.6 13.1 3.6 9.9 4.4 11.4 8.1 10.5 21.3 6.5 6.5 24.3 3.1 18.1 23.2 6.9 5.7 5.0 4.2 5.5 7.4 38.8 9.0 1.6 30.7 10.8 22.5 12.9 12.6 20.7 8.1 7.4 4.8 38.1 7.9 7.8 2.5 44.3 21.2 9.7 23.1 17.0 12.1 2.6 31.6 3.8 13.6 14.6 17.5 2.8 8.2 16.0 38.7 16.7 12.0 0.9 15.4 14.8 10.0 3.6 7.8 9.7 1.9 10.0 49.8 21.1 17.4 11.5 34.6 5.0 5.7 13.3 10.1 13.2 18.7 0.0 0.1 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.4 0.7 0.2 0.3 0.0 0.3 0.0 0.3 0.7 0.1 4.7 10.0 7.2 16.1 7.6 3.0 8.4 5.2 9.4 2.0 10.3 11.4 10.3 0.0 1.3 70.5 14.5 6.1 5.4 2.0 6.8 16.5 8.2 8.0 21.3 1.5 1.4 1.8 0.0 0.4 15.3 0.2 0.0 9.0 13.1 5.6 28.1 11.6 1.2 9.7 86.3 10.4 1.5 17.4 3.1 3.3 2.5 18.8 3.6 0.7 3.4 25.2 108.2 0.4 2.0 4.9 19.4 11.6 4.1 8.1 8.8 19.7 3.9 13.6 6.2 76.4 111.0 16.7 0.2 5.3 12.9 8.1 0.0 1.3 1.2 5.3 13.1 45.6 20.9 20.5 9.5 5.3 5.1 0.0 18.1 20.0 0.8 2.9 SAMD4A "DKFZP434H0350, hSmaug1, KIAA1053, SAMD4, Smaug, SMG, SMGA" ENSG00000020577 "Sterile alpha motif domain containing 4A" Q9UPU9 14 54566117-54793315 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 94.3;testis: 107.9" "Group enriched" "Detected in many" 4 "Early spermatids: 1176.0;Late spermatids: 2275.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043061, HPA065309" Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" Cytosol "HPA043061: AB_2678299, HPA065309: AB_2685462" "unprognostic (1.46e-1)" "unprognostic (8.10e-3)" "unprognostic (9.66e-3)" "unprognostic (1.18e-4)" "unprognostic (2.79e-1)" "unprognostic (6.37e-2)" "unprognostic (1.46e-1)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (1.09e-2)" "unprognostic (2.83e-2)" "unprognostic (8.27e-2)" "unprognostic (5.41e-2)" "unprognostic (1.51e-1)" 16.6 4.2 27.4 8.9 33.1 0.4 13.1 42.3 24.9 13.0 14.1 37.6 3.2 26.1 4.0 6.7 12.0 6.0 47.8 22.6 40.3 12.4 16.6 21.2 4.6 79.0 46.2 4.5 6.2 3.8 6.1 9.2 69.4 14.5 4.8 2.6 7.0 9.4 94.3 8.9 10.4 17.1 64.1 7.1 10.9 107.9 41.8 1.1 7.0 39.3 3.1 17.7 12.8 60.8 32.9 2.9 6.7 3.4 14.0 21.3 11.7 27.4 41.4 22.3 22.0 36.8 7.8 1.8 14.0 41.7 8.8 22.6 6.6 14.2 32.8 16.5 2.8 0.0 4.0 7.7 7.7 0.0 0.2 12.6 5.3 15.9 23.4 6.5 17.1 0.0 2.6 0.0 11.0 2.4 0.4 0.1 3.1 0.2 7.5 0.9 13.5 0.1 11.0 10.8 1.0 10.7 4.0 5.2 15.9 13.8 21.0 0.3 37.1 26.6 41.1 6.6 8.7 0.1 0.1 0.0 7.5 0.6 8.4 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 27.4 33.1 42.3 24.9 22.6 40.3 79.0 46.2 69.4 64.1 41.8 60.8 16.0 25.6 1.5 170.1 7.4 39.6 47.0 12.0 1.2 2.4 6.2 6.1 278.5 14.3 9.9 18.4 8.4 10.5 1.6 4.4 3.9 9.9 1176.0 13.7 45.3 30.9 6.0 5.7 64.6 8.0 1.8 47.3 1.5 29.3 22.8 0.8 10.8 62.6 11.6 10.1 173.7 1.5 6.1 15.3 28.9 2275.7 14.6 13.0 24.9 72.1 12.8 1.5 1.0 380.5 140.7 19.8 5.5 23.7 0.3 55.1 5.6 22.9 4.0 5.4 13.1 79.7 37.1 17.1 7.6 0.4 24.3 1.9 5.7 0.3 1.7 44.5 SCN8A "CerIII, CIAT, MED, NaCh6, Nav1.6, PN4" ENSG00000196876 "Sodium voltage-gated channel alpha subunit 8" Q9UQD0 12 51590266-51812864 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 35.0" "Group enriched" "Detected in many" 8 "Excitatory neurons: 336.7;Inhibitory neurons: 280.1;Oligodendrocyte precursor cells: 104.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 35.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.7;ASC TERT1: 13.5;WM-115: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022169, HPA043937, HPA073590" Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Vesicles, Cell Junctions" "CAB022169: , HPA043937: , HPA073590: " "unprognostic (2.96e-2)" "unprognostic (8.49e-2)" "unprognostic (6.93e-2)" "unprognostic (3.52e-6)" "unprognostic (8.13e-2)" "unprognostic (1.51e-2)" "unprognostic (1.16e-1)" "unprognostic (7.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.16e-1)" "unprognostic (4.73e-4)" "unprognostic (1.69e-2)" "unprognostic (1.29e-5)" "unprognostic (4.38e-1)" "unprognostic (1.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.75e-2)" 0.2 1.0 5.6 0.4 8.9 0.7 0.5 2.5 35.0 0.4 0.0 0.7 0.2 0.4 0.7 0.1 0.2 0.9 0.1 11.4 0.2 0.9 2.6 0.1 0.4 4.2 0.0 0.5 1.6 0.5 6.7 0.1 3.8 0.6 0.9 7.9 0.6 0.2 0.3 0.3 0.2 0.1 0.0 0.6 1.0 1.7 2.4 0.5 0.5 0.1 0.2 0.2 0.2 11.5 1.7 1.3 13.7 0.2 1.8 13.5 0.3 8.0 12.5 9.1 8.5 2.8 1.6 0.4 1.9 9.9 4.4 0.1 2.3 0.0 10.5 1.6 0.8 0.1 0.3 0.3 0.1 0.2 1.1 1.8 0.0 6.5 1.4 3.4 9.8 3.5 0.2 0.2 5.5 1.0 2.5 0.2 4.9 0.9 4.8 0.1 0.7 0.0 0.0 0.5 5.6 2.2 4.5 2.1 0.3 2.1 0.4 0.2 2.8 8.9 6.3 3.3 5.2 0.2 0.1 0.0 1.8 1.9 13.0 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.0 0.0 5.6 8.9 2.5 35.0 11.4 0.2 4.2 0.0 3.8 0.0 2.4 11.5 1.2 0.0 0.0 27.1 0.0 0.0 0.5 0.0 3.4 16.7 2.6 1.8 1.4 1.5 0.0 0.0 10.4 0.0 0.3 1.0 0.0 0.5 0.6 0.0 0.7 1.3 11.4 0.0 336.7 0.5 0.0 0.1 3.1 0.0 0.0 0.7 1.1 4.3 0.0 5.0 280.1 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 20.6 0.0 4.7 0.0 104.5 14.2 0.7 0.5 0.7 0.0 0.4 0.0 0.7 0.0 11.2 0.0 0.4 0.3 3.8 10.2 0.1 0.0 0.0 0.3 0.0 0.9 0.3 SCN9A "ETHA, Nav1.7, NE-NA, NENA, PN1" ENSG00000169432 "Sodium voltage-gated channel alpha subunit 9" Q15858 2 166195185-166376001 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 21.9" "Cell type enhanced" "Detected in many" "dendritic cells: 43.2;Hofbauer cells: 67.5;Inhibitory neurons: 48.2;Langerhans cells: 42.8;Oligodendrocyte precursor cells: 133.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.6" "Cell line enhanced" "Detected in many" "BJ: 23.0;BJ hTERT+: 16.8;HHSteC: 19.0;hTERT-RPE1: 15.6" "Region enriched" "Detected in many" 5 "hypothalamus: 9.3" "Low region specificity" "Detected in many" "CAB013679, HPA061843" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB013679: , HPA061843: AB_2684625" "unprognostic (2.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (8.98e-5)" "unprognostic (1.47e-3)" "unprognostic (9.43e-3)" "unprognostic (2.28e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.64e-1)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.69e-3)" "unprognostic (6.74e-2)" "unprognostic (2.46e-2)" "unprognostic (2.46e-1)" 1.7 1.7 5.3 0.9 4.2 2.0 0.6 0.1 3.4 0.6 0.0 3.2 0.5 0.2 0.1 0.5 0.4 1.2 0.4 2.9 21.9 1.7 3.9 2.0 0.6 8.2 19.4 0.3 2.0 0.1 1.5 4.3 12.0 0.3 3.1 0.7 0.4 0.4 0.2 0.7 1.8 2.4 2.2 3.1 0.4 5.1 18.2 1.6 0.3 0.6 0.4 0.5 0.5 1.7 0.0 2.5 0.1 0.0 9.6 7.9 0.0 23.0 16.8 5.2 1.7 0.5 0.1 0.0 0.0 2.8 0.2 0.1 6.5 0.6 8.6 0.0 2.1 1.7 1.8 1.9 19.0 0.1 0.0 0.6 0.2 9.1 1.7 15.6 1.1 1.2 6.1 6.6 0.8 0.0 3.6 0.0 1.9 0.1 0.6 0.8 3.3 9.0 2.4 9.5 1.0 9.5 0.0 0.1 0.3 4.8 0.3 0.0 0.1 0.0 1.5 0.1 0.4 0.1 0.1 0.0 3.2 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.9 0.5 0.1 23.6 0.0 0.1 5.3 4.2 0.1 3.4 2.9 21.9 8.2 19.4 12.0 2.2 18.2 1.7 0.9 12.8 23.8 0.7 1.3 1.0 0.4 0.5 0.6 0.6 0.8 0.9 2.5 8.6 4.4 5.5 0.0 0.3 43.2 9.0 3.9 23.4 2.5 0.1 0.1 5.7 33.0 4.2 15.8 31.5 0.3 2.0 0.0 0.1 3.8 18.1 13.6 9.5 67.5 0.0 48.2 19.3 10.2 1.9 42.8 3.2 1.2 11.3 3.6 2.8 1.0 2.3 0.0 133.7 0.4 12.7 7.8 0.0 1.2 0.3 14.7 11.5 2.2 0.2 0.0 7.8 1.6 1.3 0.4 0.5 0.4 1.1 0.9 4.4 12.9 0.2 SEC24D KIAA0755 ENSG00000150961 "SEC24 homolog D, COPII coat complex component" O94855 4 118722823-118838683 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 118.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041626, HPA053486" Approved Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA041626: AB_10796348, HPA053486: AB_2682166" "unprognostic (9.06e-2)" "unprognostic (3.11e-1)" "unprognostic (3.23e-2)" "unprognostic (8.60e-3)" "unprognostic (1.05e-1)" "unprognostic (1.92e-1)" "unprognostic (1.93e-1)" "unprognostic (2.58e-1)" "unprognostic (9.39e-2)" "unprognostic (3.23e-1)" "unprognostic (1.22e-1)" "unprognostic (6.85e-2)" "prognostic unfavorable (3.42e-6)" "unprognostic (1.09e-3)" "unprognostic (5.64e-2)" "unprognostic (4.30e-3)" "unprognostic (1.37e-1)" 21.1 13.3 2.7 27.2 3.3 17.6 19.4 1.1 4.4 49.0 4.5 24.4 37.5 26.4 36.9 12.4 20.7 31.9 20.1 5.5 4.6 9.5 52.0 22.9 18.4 1.3 2.3 15.3 35.8 10.2 23.3 36.8 1.6 22.0 32.3 1.6 22.9 26.4 5.8 9.9 40.8 41.3 0.6 18.0 29.6 18.4 2.8 14.6 35.6 6.1 21.9 28.9 16.7 2.6 29.6 15.4 35.3 28.6 98.0 130.2 24.8 124.5 136.8 62.1 73.5 16.9 21.3 23.2 17.3 198.7 32.1 10.0 19.4 39.2 66.8 19.4 10.5 25.7 22.8 70.6 99.8 68.6 46.0 77.9 21.6 54.9 89.2 110.3 103.9 15.8 6.7 69.1 98.5 20.6 33.2 20.4 33.3 66.5 24.8 20.1 25.8 41.2 55.6 14.7 20.9 41.8 17.8 89.1 15.3 50.9 12.6 53.9 113.9 48.0 15.3 69.7 28.6 53.1 21.1 38.6 104.5 42.8 68.5 5.8 5.6 16.3 3.1 6.0 6.3 1.7 3.2 4.4 5.8 1.5 2.1 2.7 4.8 5.0 7.4 2.9 4.7 2.6 2.7 3.3 1.1 4.4 5.5 4.6 1.3 2.3 1.6 0.6 2.8 2.6 13.0 3.2 15.3 4.9 19.4 21.0 15.2 19.4 25.6 4.5 19.0 10.2 5.9 17.2 25.5 14.7 0.0 24.3 24.2 18.2 0.0 10.3 101.3 17.4 61.3 23.2 41.3 6.1 57.4 25.3 54.2 49.7 37.2 39.4 8.2 14.2 21.8 70.0 28.1 1.7 6.5 81.0 12.2 34.0 54.4 84.6 45.7 25.1 17.8 48.7 18.3 1.3 13.4 37.7 3.7 13.0 13.6 38.4 118.8 30.7 48.1 4.2 23.0 2.9 26.3 17.5 38.7 14.5 9.7 10.4 17.6 45.0 16.3 34.2 19.1 40.1 SEC31A "ABP125, ABP130, KIAA0905, SEC31L1" ENSG00000138674 "SEC31 homolog A, COPII coat complex component" O94979 4 82818509-82901166 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005457 Approved Supported Vesicles,Cytosol NA NA 40000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cytosol" "HPA005457: AB_1079896" "unprognostic (3.50e-2)" "unprognostic (2.28e-3)" "unprognostic (2.55e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavorable (3.32e-4)" "unprognostic (6.14e-3)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "unprognostic (4.21e-3)" "unprognostic (3.62e-1)" "unprognostic (1.64e-1)" "unprognostic (5.53e-3)" "unprognostic (2.92e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.69e-4)" 98.7 103.3 52.2 78.4 54.3 119.4 111.4 62.4 70.1 145.5 94.9 107.1 124.2 119.7 162.1 92.6 90.9 122.1 110.7 54.0 61.4 133.6 174.8 96.2 88.2 58.4 58.7 152.8 192.6 116.4 108.4 143.2 58.7 113.4 127.2 87.9 134.0 111.3 96.8 107.8 111.0 131.5 50.9 76.5 110.1 77.8 54.4 93.8 168.0 85.6 102.1 113.1 94.1 63.9 146.2 65.2 183.6 130.4 318.9 394.5 133.3 264.8 295.4 146.0 179.2 113.2 182.3 188.3 113.7 532.2 84.6 68.1 183.3 176.2 200.4 193.4 72.7 115.3 110.5 302.1 316.4 124.4 140.7 380.5 217.7 223.5 254.3 251.2 240.5 83.8 178.4 181.1 264.2 128.6 164.9 99.6 126.1 154.0 58.3 121.2 100.1 140.3 237.2 83.0 118.6 131.2 105.7 180.7 174.9 184.8 142.1 137.8 248.2 190.7 98.9 169.0 168.8 135.1 62.4 256.7 190.6 147.8 224.2 84.3 66.9 51.2 65.1 74.0 80.5 60.0 57.6 64.3 73.3 50.0 56.9 54.6 19.2 89.9 83.1 61.1 52.7 71.8 52.2 54.3 62.4 70.1 54.0 61.4 58.4 58.7 58.7 50.9 54.4 63.9 62.6 105.8 85.3 50.9 58.1 60.5 60.5 64.1 56.9 52.3 54.5 43.7 85.5 51.5 109.8 47.8 54.2 57.3 61.0 62.8 27.4 65.8 30.6 90.1 164.6 65.0 38.3 41.2 61.0 71.2 85.3 125.2 100.9 119.7 75.2 241.0 65.0 94.0 45.9 42.1 60.0 99.4 50.8 51.2 55.3 19.3 139.1 63.8 51.6 67.5 60.4 36.5 38.1 74.9 72.6 67.5 46.3 126.0 152.2 76.3 121.0 65.9 100.5 66.9 52.6 86.5 98.9 30.3 34.6 62.2 74.2 81.5 55.4 78.9 54.9 101.1 SEC61A1 ENSG00000058262 "SEC61 translocon subunit alpha 1" P61619 3 128051641-128071683 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022076 Supported "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "CAB022076: " "unprognostic (1.84e-1)" "unprognostic (8.00e-2)" "unprognostic (8.21e-2)" "prognostic favorable (7.82e-4)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (2.84e-2)" "unprognostic (4.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.85e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (6.84e-9)" "unprognostic (2.73e-2)" "unprognostic (3.18e-2)" "unprognostic (8.33e-2)" "unprognostic (2.51e-2)" 82.1 100.7 31.3 88.3 33.4 79.5 75.3 33.5 34.7 144.5 52.4 90.7 81.9 88.9 128.9 88.7 78.1 81.7 74.2 32.3 39.6 64.6 134.8 93.3 60.2 40.9 37.6 67.3 272.1 111.7 93.5 112.8 36.0 90.0 90.0 37.0 176.3 97.0 70.5 66.9 75.8 110.7 36.6 73.7 105.5 38.8 46.6 61.4 104.8 59.3 80.6 97.0 68.7 35.8 272.8 136.5 132.0 240.3 367.9 317.3 256.9 426.9 470.8 349.0 371.2 259.1 186.9 184.7 259.5 534.8 266.2 232.6 209.0 291.3 334.2 168.1 126.2 213.5 143.5 273.6 542.9 264.1 225.9 348.1 345.4 329.3 422.4 265.0 314.3 122.2 136.9 415.3 412.8 237.7 135.1 87.5 184.6 231.6 202.8 144.2 125.5 349.8 181.4 229.3 155.8 162.4 216.0 193.5 270.7 152.0 184.2 215.1 327.3 278.3 164.7 333.7 201.4 386.6 210.6 265.8 456.3 166.2 369.1 160.3 88.6 67.0 89.0 79.6 120.0 43.8 62.9 78.2 82.6 26.1 38.8 46.2 22.5 65.0 84.2 114.0 45.1 116.9 31.3 33.4 33.5 34.7 32.3 39.6 40.9 37.6 36.0 36.6 46.6 35.8 31.9 32.1 33.1 18.6 46.6 37.0 25.7 44.4 30.7 17.0 63.5 41.3 15.0 37.1 43.3 49.7 35.5 64.3 59.2 107.2 3.9 81.0 42.2 28.2 72.9 45.9 73.6 19.5 12.6 154.5 136.3 57.4 77.5 68.6 26.0 55.6 49.6 118.2 75.9 26.9 18.5 150.8 38.7 34.8 32.1 25.7 41.0 38.2 33.8 26.2 32.1 22.4 28.8 19.1 17.2 104.9 50.2 43.6 192.8 69.6 63.5 26.8 31.0 15.5 32.9 25.6 47.2 12.3 18.4 42.5 29.5 127.9 32.4 52.6 100.4 44.6 SELENOM "SELM, SEPM" ENSG00000198832 "Selenoprotein M" Q8WWX9 22 31104772-31120069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 373.6;Breast myoepithelial cells: 436.2;Collecting duct cells: 309.0;Distal tubular cells: 309.1;Endometrial stromal cells: 349.5;Exocrine glandular cells: 586.6;Smooth muscle cells: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 154.8;T-cells: 233.0" "Cell line enhanced" "Detected in many" "BJ: 152.2;BJ hTERT+: 143.8;HHSteC: 183.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008667, HPA019601" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 170000 "Cluster 20: T-cells - T-cell receptor" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "CAB008667: AB_1622762, HPA019601: AB_1856666" "unprognostic (5.29e-3)" "unprognostic (1.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.59e-3)" "unprognostic (1.45e-1)" "unprognostic (1.60e-2)" "unprognostic (1.60e-1)" "unprognostic (3.51e-3)" "unprognostic (8.31e-2)" "prognostic unfavorable (2.55e-6)" "unprognostic (1.32e-2)" "unprognostic (3.80e-1)" "unprognostic (5.20e-2)" "unprognostic (3.19e-2)" 241.8 95.4 126.7 55.7 126.7 2.9 239.8 127.3 170.7 458.8 189.9 575.4 37.2 600.2 14.8 86.1 437.8 28.6 227.2 130.0 149.3 162.5 36.7 157.5 25.9 137.1 138.6 262.4 154.3 94.7 241.1 32.2 131.0 339.6 16.4 8.1 198.8 140.1 109.9 114.8 193.9 85.3 139.6 97.6 285.6 42.1 142.1 10.2 225.8 18.6 15.3 462.3 290.7 132.3 12.8 25.7 7.4 42.7 68.8 80.5 82.2 152.2 143.8 69.2 50.0 0.8 2.0 1.6 30.9 89.9 31.2 1.2 6.9 9.2 4.7 7.0 25.6 2.7 7.8 13.3 183.7 0.0 13.1 78.5 27.1 33.1 12.6 33.1 9.0 2.2 2.4 14.7 17.9 6.6 0.5 1.4 9.6 11.8 27.3 0.1 0.1 18.1 11.1 0.1 16.2 35.7 47.3 41.6 0.7 2.5 57.5 0.9 30.9 20.8 59.0 77.8 0.1 13.2 6.5 1.0 83.1 0.2 13.8 18.3 10.5 5.1 105.3 19.9 137.9 154.8 174.5 127.0 6.4 129.5 233.0 137.8 8.2 39.1 40.1 2.5 179.0 102.6 126.7 126.7 127.3 170.7 130.0 149.3 137.1 138.6 131.0 139.6 142.1 132.3 168.6 54.5 126.5 0.0 38.8 0.0 0.0 0.0 0.0 0.0 373.6 436.2 0.0 0.0 32.2 309.0 0.0 11.7 23.2 0.0 309.1 101.2 0.0 22.8 349.5 61.8 0.0 0.0 0.0 586.6 149.5 161.3 0.0 18.1 30.3 30.8 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 42.9 0.0 0.0 0.0 0.0 166.2 0.0 0.0 22.3 0.0 0.0 152.5 20.4 0.0 0.0 0.0 225.6 0.0 0.0 0.0 0.0 23.4 24.8 30.5 0.0 0.0 SEMA3A "coll-1, Hsema-I, SEMA1, SEMAD, SemD" ENSG00000075213 "Semaphorin 3A" Q14563 7 83955777-84492724 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.6" "Cell type enhanced" "Detected in many" "Astrocytes: 58.4;Cone photoreceptor cells: 45.9;Excitatory neurons: 89.7;Rod photoreceptor cells: 66.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.5" "Lineage enriched" "Detected in single" 16 "monocytes: 1.5" "Cell line enhanced" "Detected in many" "AF22: 129.3;BJ: 102.9;fHDF/TERT166: 112.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029447, HPA052235" Approved Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA 1600000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA029447: AB_10602302, HPA052235: AB_2681770" "unprognostic (1.20e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (1.51e-1)" "unprognostic (5.82e-2)" "unprognostic (1.37e-2)" "unprognostic (5.98e-3)" "unprognostic (2.92e-3)" "unprognostic (6.05e-3)" "unprognostic (1.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.46e-1)" "unprognostic (4.44e-2)" "unprognostic (6.18e-12)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.61e-2)" "unprognostic (1.47e-4)" 6.8 0.2 3.8 3.8 5.8 0.1 1.5 0.6 3.0 4.4 0.0 9.8 1.4 1.0 2.2 5.8 1.6 5.6 2.5 2.0 0.7 0.4 0.4 2.3 3.3 3.8 0.2 0.4 0.4 0.5 2.1 10.4 4.6 2.9 5.7 22.6 0.4 0.4 0.1 1.1 2.4 4.7 0.6 3.8 2.0 1.2 0.3 0.5 1.7 0.5 1.6 5.4 0.6 4.4 11.8 32.8 129.3 0.1 3.8 3.1 8.4 102.9 60.0 8.5 5.3 11.4 30.7 0.0 4.8 112.0 1.1 57.0 0.3 24.6 11.8 0.0 4.2 0.0 6.0 0.0 3.3 2.6 0.0 3.9 0.0 18.1 4.4 26.2 32.1 0.1 0.1 0.2 3.4 0.6 0.0 0.0 48.6 0.5 11.6 2.3 55.3 3.4 18.5 0.8 9.8 5.2 0.8 0.2 1.1 20.7 0.6 1.1 18.3 11.2 11.6 32.6 15.1 7.6 5.5 0.0 11.5 4.5 22.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 3.8 5.8 0.6 3.0 2.0 0.7 3.8 0.2 4.6 0.6 0.3 4.4 1.0 3.2 1.7 58.4 0.0 0.9 0.0 15.4 0.0 15.1 0.2 0.3 6.0 0.0 22.4 0.0 45.9 0.4 0.3 0.1 0.0 0.1 0.2 2.0 0.7 7.3 0.0 0.0 89.7 2.0 0.2 9.3 0.0 9.0 1.3 3.5 1.8 0.1 1.0 3.3 10.0 0.0 2.0 0.3 2.7 0.2 2.5 0.5 1.8 7.5 0.0 19.6 0.0 9.5 5.8 5.5 0.0 0.0 0.0 0.3 0.0 0.0 15.6 66.3 0.0 1.5 2.1 1.7 1.9 0.4 1.3 0.3 1.1 18.6 0.0 0.2 SEPTIN10 "FLJ11619, SEPT10" ENSG00000186522 "Septin 10" Q9P0V9 2 109542799-109614143 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 56.4;Cardiomyocytes: 21.8;Cytotrophoblasts: 15.1;Extravillous trophoblasts: 59.4;Fibroblasts: 15.5;Hofbauer cells: 19.6;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 3.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047860, HPA056304, HPA060310" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA047860: AB_2680187, HPA056304: AB_2683094, HPA060310: AB_2684249" "unprognostic (1.84e-1)" "unprognostic (4.29e-3)" "unprognostic (1.94e-2)" "unprognostic (3.18e-2)" "unprognostic (6.34e-2)" "unprognostic (3.41e-2)" "unprognostic (2.02e-3)" "unprognostic (1.80e-2)" "unprognostic (9.67e-2)" "unprognostic (8.61e-2)" "unprognostic (1.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.58e-2)" "unprognostic (3.05e-3)" "unprognostic (2.72e-1)" "unprognostic (2.55e-1)" "unprognostic (9.12e-2)" 57.0 24.2 16.1 22.6 29.5 0.7 52.9 29.8 20.3 41.5 58.7 52.0 22.3 44.5 21.7 88.4 33.4 41.8 41.7 15.1 24.2 43.4 66.5 60.4 18.4 46.8 29.5 46.7 20.3 26.9 9.5 50.4 41.6 40.6 39.8 13.6 34.7 42.2 28.5 73.4 24.3 58.0 31.9 36.3 30.5 76.9 26.1 19.9 43.3 39.0 22.8 55.1 43.2 44.5 104.7 27.7 99.6 64.1 78.1 145.8 61.1 166.5 290.6 114.8 133.3 52.2 59.0 0.0 82.2 130.4 72.2 47.7 42.8 105.2 151.6 199.4 31.2 0.2 38.5 75.3 58.7 0.2 13.4 91.5 46.9 103.5 135.1 123.9 154.3 0.0 2.7 0.4 141.5 9.9 0.1 10.3 74.4 61.3 53.7 0.1 80.9 17.4 95.7 136.8 29.6 61.8 97.8 2.1 77.0 115.2 26.5 1.2 158.5 120.1 85.1 46.9 69.6 61.4 36.0 0.9 106.7 2.3 148.1 0.0 2.4 0.0 0.1 1.6 0.1 0.8 1.5 0.4 0.6 0.3 0.7 0.2 0.1 0.0 1.0 0.0 3.5 0.8 16.1 29.5 29.8 20.3 15.1 24.2 46.8 29.5 41.6 31.9 26.1 44.5 56.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 15.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 59.4 15.5 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 7.5 0.1 0.0 0.0 0.0 SEPTIN11 "FLJ10849, SEPT11" ENSG00000138758 "Septin 11" Q9NVA2 4 76949751-77040384 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 90.1;Extravillous trophoblasts: 266.8;Fibroblasts: 40.1;Hofbauer cells: 52.0;Syncytiotrophoblasts: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 495.8;fHDF/TERT166: 604.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003459, HPA005665" Approved Approved Cytosol NA NA 2800000 "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA003459: AB_1856696, HPA005665: AB_1079910" "unprognostic (1.69e-1)" "unprognostic (2.93e-1)" "unprognostic (3.39e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (1.79e-1)" "unprognostic (6.04e-3)" "unprognostic (1.58e-2)" "unprognostic (2.58e-2)" "unprognostic (5.85e-2)" "prognostic favorable (2.40e-4)" "unprognostic (5.70e-3)" "unprognostic (6.84e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" 84.8 13.0 34.6 27.5 46.5 7.9 39.3 24.3 51.4 40.4 0.0 50.1 21.8 33.8 18.0 22.5 17.4 45.4 30.8 40.5 13.7 52.4 33.9 40.5 24.1 5.2 8.5 20.0 22.3 17.3 11.3 84.1 4.5 21.0 40.4 22.3 11.6 26.1 26.0 13.3 35.3 40.6 0.0 25.6 25.2 7.8 16.6 12.7 21.1 18.3 22.8 39.3 21.5 50.6 87.6 34.9 328.1 293.8 192.8 152.9 94.6 495.8 382.7 110.6 154.5 64.3 62.9 2.0 100.9 604.4 51.9 36.6 109.8 73.8 171.2 114.0 36.7 171.2 44.6 47.1 168.0 93.0 69.7 195.5 34.4 160.2 59.8 87.7 169.0 34.3 72.0 46.6 331.2 50.4 122.8 3.3 111.1 71.4 18.1 142.6 372.8 10.1 62.6 94.0 112.1 83.6 96.2 54.4 77.9 209.9 49.5 37.3 184.4 368.7 109.4 182.8 93.1 28.5 24.3 1.1 140.5 10.0 76.4 12.2 2.4 32.5 8.1 2.2 5.0 3.6 9.2 11.2 7.8 6.7 3.5 9.4 0.6 38.4 7.4 20.8 5.8 6.6 34.6 46.5 24.3 51.4 40.5 13.7 5.2 8.5 4.5 0.0 16.6 50.6 33.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 90.1 24.6 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 266.8 40.1 0.0 0.0 0.0 0.0 0.0 0.0 52.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.0 0.0 0.0 60.5 5.6 0.0 0.0 0.0 SERPINB8 "CAP2, PI8" ENSG00000166401 "Serpin family B member 8" P50452 18 63970029-64019779 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 58.8" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 120.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB034300 Enhanced Approved Nucleoplasm,Cytosol NA NA 920000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB034300: AB_2186486" "unprognostic (8.49e-2)" "unprognostic (4.87e-2)" "unprognostic (4.10e-3)" "unprognostic (2.86e-2)" "unprognostic (1.52e-2)" "unprognostic (7.71e-2)" "unprognostic (4.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.58e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (8.73e-2)" "unprognostic (3.48e-2)" "unprognostic (1.25e-1)" "unprognostic (1.90e-1)" 10.8 9.5 2.6 15.8 3.2 30.3 9.5 3.4 3.6 9.3 3.5 8.6 6.3 4.7 1.5 30.1 4.4 18.1 5.7 2.8 3.9 9.0 37.8 12.1 13.4 5.2 4.0 4.2 7.1 2.7 3.7 7.2 4.8 4.6 9.7 2.3 10.8 3.3 3.0 58.8 8.8 7.3 4.3 7.8 7.1 2.7 4.6 6.5 5.3 2.3 18.3 23.7 17.1 4.5 24.2 4.8 4.0 28.8 13.9 19.7 2.0 75.6 72.9 46.8 46.4 1.0 10.8 0.4 27.2 45.6 23.3 38.3 0.8 48.2 66.3 33.4 0.9 0.0 8.7 2.5 32.1 120.0 10.0 19.1 41.3 63.6 20.9 30.3 51.4 5.1 0.7 13.4 32.9 2.1 2.1 13.5 1.7 3.8 23.6 1.7 10.5 2.1 21.4 27.1 2.3 2.4 15.0 2.3 28.8 3.3 0.8 45.4 79.2 71.0 15.4 8.8 31.1 5.9 1.0 0.1 72.5 69.2 63.0 2.7 44.2 2.0 7.6 34.2 6.8 7.1 6.3 4.7 53.8 9.9 3.3 5.2 12.4 4.6 18.1 28.8 8.9 11.2 2.6 3.2 3.4 3.6 2.8 3.9 5.2 4.0 4.8 4.3 4.6 4.5 6.0 3.2 8.3 0.3 9.1 41.0 25.9 38.9 5.7 0.4 5.5 3.8 1.2 8.6 25.5 0.0 0.0 4.9 13.4 12.3 0.0 30.0 1.3 7.6 3.3 8.7 1.8 3.0 1.8 19.2 5.6 8.6 8.2 16.3 4.5 0.9 7.5 9.6 15.3 0.0 1.3 3.5 12.2 24.8 35.1 1.1 0.9 35.9 16.0 1.0 29.0 1.6 5.2 1.5 2.9 42.2 10.7 0.0 3.5 13.0 8.5 2.9 12.9 0.3 0.0 12.3 9.8 1.7 2.3 18.2 48.4 31.3 8.2 1.4 5.0 33.3 SERTAD2 "KIAA0127, Sei-2, TRIP-Br2" ENSG00000179833 "SERTA domain containing 2" Q14140 2 64631621-64751005 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 85.7" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 177.6;Basal squamous epithelial cells: 153.1;Suprabasal keratinocytes: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019021, HPA020904" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA019021: AB_1856740, HPA020904: AB_1856741" "unprognostic (1.40e-2)" "unprognostic (7.41e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (4.03e-4)" "unprognostic (2.15e-2)" "unprognostic (8.15e-2)" "unprognostic (3.39e-3)" "unprognostic (1.06e-1)" "unprognostic (9.55e-2)" "unprognostic (5.95e-3)" "unprognostic (1.98e-3)" "unprognostic (7.04e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.21e-3)" "unprognostic (6.78e-2)" "unprognostic (4.98e-2)" "unprognostic (3.84e-1)" 14.1 6.7 4.3 13.8 5.8 85.7 9.4 5.3 5.5 12.7 3.8 8.5 6.2 8.6 7.9 22.8 6.9 9.4 10.3 5.0 4.5 7.5 14.6 9.7 19.2 6.3 5.9 13.5 6.6 10.7 3.6 12.6 5.8 9.3 8.7 15.6 11.7 8.5 8.6 18.8 9.0 8.1 5.4 19.3 9.2 7.2 5.3 35.3 8.1 9.6 27.3 15.9 16.8 7.1 30.9 9.0 16.5 16.6 13.9 35.2 18.9 24.2 23.2 14.1 13.2 23.1 23.0 26.0 13.0 39.8 19.6 12.0 10.9 14.8 29.6 2.5 16.4 17.2 8.8 16.8 3.1 15.3 8.4 24.0 19.1 32.2 20.9 21.1 8.6 12.7 10.9 14.1 33.2 7.4 16.5 16.7 9.0 16.9 23.6 14.3 28.2 10.2 19.1 28.0 19.1 7.5 17.1 11.9 31.5 15.3 7.9 12.1 26.1 75.7 39.1 44.8 19.9 24.0 9.8 29.6 28.0 27.7 30.3 1.3 1.6 2.3 0.9 1.5 0.5 2.5 0.9 1.0 1.5 2.5 2.2 1.6 2.0 1.5 1.8 4.9 0.5 0.9 4.3 5.8 5.3 5.5 5.0 4.5 6.3 5.9 5.8 5.4 5.3 7.1 25.6 6.4 23.6 22.9 40.8 177.6 40.9 22.5 153.1 24.8 28.7 28.6 26.4 32.9 25.9 9.2 18.8 38.6 33.0 31.6 1.9 12.8 51.2 57.8 18.5 35.4 11.3 26.5 27.3 10.0 42.8 35.1 17.3 97.7 8.8 4.8 25.4 24.1 23.6 10.1 19.8 17.1 18.3 39.3 84.7 35.4 17.1 43.6 39.2 38.4 27.4 20.0 14.4 19.6 35.5 20.7 45.4 10.5 28.1 43.9 11.6 9.5 24.9 24.3 13.1 26.8 31.0 10.8 6.7 135.4 148.3 60.1 25.5 3.7 13.3 71.5 SETD7 "KIAA1717, KMT7, SET7, SET7/9, Set9" ENSG00000145391 "SET domain containing 7, histone lysine methyltransferase" Q8WTS6 4 139495941-139606699 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058111 Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA058111: AB_2683607" "prognostic unfavorable (8.28e-4)" "unprognostic (7.07e-2)" "unprognostic (4.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.92e-1)" "unprognostic (4.82e-2)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.71e-2)" "unprognostic (9.10e-2)" "unprognostic (6.44e-2)" "unprognostic (7.75e-2)" "unprognostic (1.37e-1)" "unprognostic (6.16e-3)" "unprognostic (1.17e-1)" "unprognostic (6.92e-2)" "unprognostic (6.56e-3)" 44.7 18.5 17.8 15.1 17.7 9.7 27.3 19.3 17.3 40.5 21.2 23.5 7.3 33.0 12.6 28.1 18.8 26.7 41.0 16.6 19.4 10.1 50.1 19.2 11.7 25.0 20.3 19.6 21.9 34.7 8.8 19.1 24.7 35.1 15.3 11.5 16.2 20.6 106.6 22.7 12.1 34.8 24.6 17.0 20.1 14.4 24.5 10.1 14.1 73.7 15.9 23.4 18.2 29.2 28.4 37.2 13.0 7.8 77.1 65.9 29.6 65.7 67.3 32.4 27.1 22.7 37.2 68.0 25.5 110.5 22.4 13.9 44.3 51.3 52.4 32.8 33.0 8.9 45.5 0.8 38.4 31.9 12.9 57.7 58.6 52.1 54.6 41.2 41.7 27.8 5.5 96.1 42.3 46.8 21.0 4.6 6.4 40.8 23.9 19.7 48.4 37.3 31.5 25.3 55.3 18.5 44.7 63.5 15.3 12.6 25.3 28.0 68.8 57.1 40.7 68.6 55.2 89.6 86.8 42.2 65.9 31.1 28.0 0.5 3.9 0.2 0.3 2.0 2.7 1.0 1.1 1.1 4.4 1.2 0.4 0.2 0.9 0.2 3.2 2.1 3.7 1.2 17.8 17.7 19.3 17.3 16.6 19.4 25.0 20.3 24.7 24.6 24.5 29.2 28.7 6.4 18.8 17.3 8.9 17.2 14.5 14.1 12.5 5.4 24.0 14.7 43.1 20.0 15.0 9.2 12.5 26.2 4.2 4.1 0.0 22.7 1.3 3.5 35.9 29.4 1.2 3.6 21.1 21.2 16.7 39.8 16.8 7.5 2.5 2.9 37.1 70.6 20.4 8.4 42.4 13.6 18.3 31.0 20.9 4.3 23.0 19.5 10.6 19.7 19.0 15.0 0.0 36.2 29.2 22.4 4.1 28.2 13.2 38.4 1.3 4.5 14.0 12.9 19.7 35.2 23.3 3.7 2.7 17.9 22.0 46.1 9.8 9.5 11.7 20.4 SGCG "A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE" ENSG00000102683 "Sarcoglycan gamma" Q13326 13 23180979-23325162 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 118.8;skeletal muscle: 158.0;tongue: 144.1" "Cell type enriched" "Detected in some" 10 "Cardiomyocytes: 134.3" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 4 "cerebral cortex: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 66.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA007476 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA007476: AB_1079946" "unprognostic (5.19e-2)" "unprognostic (8.28e-2)" "unprognostic (5.15e-3)" "unprognostic (1.64e-4)" "unprognostic (3.00e-3)" "unprognostic (3.61e-2)" "unprognostic (8.14e-3)" "unprognostic (1.46e-1)" "unprognostic (2.29e-1)" "unprognostic (4.49e-1)" "unprognostic (6.05e-2)" "unprognostic (2.23e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (2.98e-3)" "unprognostic (1.07e-1)" 14.3 0.6 0.0 0.1 0.1 0.0 2.2 0.0 1.9 0.4 0.0 1.1 0.1 0.1 8.0 3.3 1.1 0.8 118.8 0.1 0.0 0.3 0.0 4.8 0.0 0.3 0.0 0.2 0.1 2.1 0.3 0.0 0.2 3.2 0.6 0.3 4.3 0.4 158.0 3.4 0.6 0.1 0.0 0.1 0.9 1.5 0.2 0.1 0.1 144.1 0.1 3.0 1.4 0.4 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 66.6 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.2 0.0 0.2 0.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.4 0.0 0.1 0.0 0.2 0.4 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.1 0.0 0.3 0.0 0.2 0.0 0.2 0.4 0.2 0.0 0.0 0.3 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.1 134.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 1.3 0.0 0.0 12.5 0.0 0.0 11.2 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 1.6 0.0 0.0 0.0 3.4 3.0 7.5 0.2 5.4 1.0 0.0 0.0 0.0 0.5 1.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 1.2 3.8 13.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 SGIP1 DKFZp761D221 ENSG00000118473 "SH3GL interacting endocytic adaptor 1" Q9BQI5 1 66533383-66751139 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 131.4" "Group enriched" "Detected in many" 4 "Astrocytes: 390.1;Cone photoreceptor cells: 350.3;Excitatory neurons: 323.3;Inhibitory neurons: 401.5;Oligodendrocyte precursor cells: 482.0;Oligodendrocytes: 363.6;Rod photoreceptor cells: 344.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 29.9;BJ hTERT+: 38.0;fHDF/TERT166: 24.5;hTERT-RPE1: 15.8;RPTEC TERT1: 27.5;SH-SY5Y: 15.3;U-138 MG: 27.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017963 Approved Approved Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA017963: AB_10964882" "unprognostic (1.74e-2)" "unprognostic (2.77e-1)" "unprognostic (2.86e-1)" "unprognostic (1.07e-1)" "unprognostic (1.74e-1)" "unprognostic (9.04e-2)" "unprognostic (9.51e-2)" "unprognostic (7.64e-2)" "unprognostic (1.86e-1)" "unprognostic (1.61e-1)" "unprognostic (1.83e-1)" "unprognostic (1.95e-1)" "unprognostic (3.48e-7)" "unprognostic (1.77e-2)" "unprognostic (1.29e-1)" "unprognostic (4.25e-2)" "unprognostic (9.63e-2)" 7.4 4.3 12.2 1.9 15.5 0.2 2.7 6.3 17.4 10.4 0.0 3.1 1.6 10.6 4.6 2.7 3.8 4.6 5.0 15.3 5.8 18.0 0.7 8.3 0.7 5.1 5.7 1.6 0.5 0.2 7.7 1.9 5.3 5.8 1.5 131.4 1.7 5.0 2.5 1.6 2.0 3.8 1.6 0.3 3.3 4.4 5.5 0.7 8.9 1.2 0.4 2.7 5.4 10.1 0.0 0.0 0.0 0.0 0.9 5.5 0.0 29.9 38.0 2.3 3.4 0.0 0.0 0.0 0.1 24.5 0.2 0.0 0.0 0.1 4.3 0.0 0.0 1.1 0.4 0.0 6.5 0.0 0.0 4.1 0.0 2.3 0.0 15.8 11.3 0.2 0.0 0.0 13.8 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 27.5 0.0 0.7 15.3 0.0 0.0 0.0 0.6 0.0 1.1 1.9 27.3 0.0 0.7 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 15.5 6.3 17.4 15.3 5.8 5.1 5.7 5.3 1.6 5.5 10.1 5.0 0.0 0.0 390.1 0.1 1.0 0.3 0.4 0.0 89.8 0.2 4.7 2.5 2.8 0.0 9.2 350.3 0.1 0.0 0.1 7.9 0.5 0.6 2.9 7.8 13.8 0.0 0.0 323.3 0.0 0.0 15.8 0.5 5.7 10.1 0.0 0.4 0.2 0.2 74.0 401.5 0.0 0.0 0.0 1.1 1.2 2.1 0.4 10.6 48.7 0.0 49.4 0.0 482.0 363.6 0.0 0.0 11.3 0.8 0.8 0.0 0.2 0.0 344.1 13.1 3.2 32.2 0.2 0.4 0.1 1.0 0.3 0.5 0.0 0.1 0.3 SH2D4A "FLJ20967, PPP1R38, SH2A" ENSG00000104611 "SH2 domain containing 4A" Q9H788 8 19313693-19396218 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 87.7;Pancreatic endocrine cells: 99.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 181.7;OE19: 102.5;U-2197: 130.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001871, HPA001919" Enhanced Enhanced Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA001871: AB_1079949, HPA001919: AB_1079947" "unprognostic (9.08e-2)" "unprognostic (8.40e-3)" "unprognostic (4.04e-3)" "unprognostic (2.72e-3)" "unprognostic (3.51e-2)" "unprognostic (4.07e-3)" "unprognostic (2.25e-1)" "unprognostic (2.68e-1)" "unprognostic (1.67e-1)" "unprognostic (2.70e-2)" "unprognostic (8.84e-3)" "unprognostic (2.81e-1)" "prognostic favorable (6.02e-8)" "unprognostic (1.67e-2)" "unprognostic (2.18e-1)" "unprognostic (3.51e-3)" "unprognostic (4.11e-2)" 5.0 8.8 1.6 4.1 1.4 0.1 6.2 1.2 2.0 13.6 1.9 13.6 12.7 4.0 1.7 20.4 9.1 11.1 3.1 1.6 1.5 12.6 39.1 15.8 1.0 1.6 1.6 36.9 13.1 18.2 1.4 17.7 1.9 7.4 10.8 9.6 24.0 10.1 0.6 7.2 12.6 2.0 1.3 3.3 29.9 2.2 1.5 1.3 16.8 1.6 7.4 18.3 10.5 2.0 60.5 67.3 0.2 0.1 6.5 8.0 44.9 73.9 36.6 70.7 68.3 55.7 53.4 0.0 17.4 181.7 11.2 30.5 2.7 20.0 73.6 0.2 1.0 0.0 40.7 8.6 38.3 1.6 0.3 7.8 24.5 48.4 8.8 42.5 0.3 0.0 0.1 0.1 12.0 27.2 0.1 0.7 15.8 102.5 25.4 0.1 0.0 19.5 19.5 62.6 4.1 0.1 66.0 70.6 0.2 10.4 13.3 5.3 1.2 22.9 0.1 130.8 22.4 0.0 0.7 0.2 23.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.2 0.0 1.8 0.1 0.0 0.0 0.1 0.0 1.6 1.4 1.2 2.0 1.6 1.5 1.6 1.6 1.9 1.3 1.5 2.0 8.5 64.1 33.9 6.5 0.9 1.5 15.0 22.2 5.2 2.2 9.4 5.6 2.0 34.3 26.2 46.0 27.1 87.7 0.3 20.1 43.0 50.3 25.3 30.9 6.0 5.4 3.0 0.0 1.5 67.0 69.4 11.7 67.8 34.4 1.3 43.3 2.5 45.5 37.7 1.7 1.0 24.8 54.9 8.5 1.6 53.5 6.2 6.3 0.0 1.9 0.6 3.5 0.0 11.1 0.3 99.1 8.3 11.3 0.4 14.6 20.5 10.9 46.9 36.2 19.7 3.0 6.5 0.5 2.8 31.9 2.6 30.6 1.0 52.0 26.3 31.2 SH3BP4 ENSG00000130147 "SH3 domain binding protein 4" Q9P0V3 2 234952017-235055714 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 83.5" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.0;plasmacytoid DC: 3.1" "Lineage enhanced" "Detected in single" "dendritic cells: 3.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037533, HPA037534" Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" "HPA037533: AB_10672903, HPA037534: AB_2675528" "unprognostic (2.16e-3)" "unprognostic (1.43e-1)" "unprognostic (2.83e-2)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (5.38e-1)" "unprognostic (2.73e-2)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (3.89e-2)" "unprognostic (1.61e-1)" "unprognostic (4.30e-1)" "prognostic favorable (2.07e-6)" "unprognostic (2.86e-2)" "unprognostic (5.08e-2)" "unprognostic (6.91e-2)" "unprognostic (1.17e-2)" 12.4 9.0 17.8 5.7 21.8 1.1 35.3 21.7 15.9 20.8 20.4 13.8 17.2 12.5 14.5 7.7 17.5 19.0 10.2 14.5 16.2 18.3 26.1 13.2 2.2 21.3 21.1 22.5 61.3 5.8 4.0 18.2 20.5 20.3 13.7 2.4 83.5 16.8 9.5 16.6 11.1 13.6 15.8 5.6 25.6 10.2 19.7 4.7 11.1 9.4 3.8 9.4 7.5 28.1 49.3 30.6 77.7 5.8 33.8 22.4 35.2 70.2 66.6 54.6 48.8 23.5 28.8 0.0 19.0 140.4 126.8 26.1 22.6 47.2 64.8 0.2 10.3 0.0 39.5 64.1 55.8 0.0 0.1 43.9 69.9 76.6 41.4 52.4 58.7 0.1 0.4 0.2 81.4 37.8 0.1 0.2 42.5 56.2 16.8 0.0 16.0 9.3 50.0 9.9 47.9 19.3 15.8 101.4 42.7 55.2 11.9 0.2 47.2 59.8 52.2 47.1 45.7 0.0 0.1 0.2 55.6 0.1 89.2 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.1 17.8 21.8 21.7 15.9 14.5 16.2 21.3 21.1 20.5 15.8 19.7 28.1 23.5 3.2 9.1 4.2 1.0 14.8 50.2 15.6 14.2 2.3 37.3 18.0 6.6 18.6 22.5 7.3 6.2 8.7 3.9 6.0 9.8 24.7 3.4 21.4 10.9 22.9 6.6 1.3 0.7 24.8 29.9 11.7 14.8 29.2 1.3 10.0 17.2 26.8 2.1 3.3 1.4 9.1 16.2 1.4 13.1 4.9 8.1 10.9 24.9 20.6 2.6 1.3 0.0 18.1 52.4 39.6 6.3 9.4 0.2 96.9 0.8 1.9 20.7 0.7 0.0 1.9 12.4 0.8 2.8 8.8 11.1 37.1 0.5 5.5 18.0 30.4 SH3BP5L KIAA1720 ENSG00000175137 "SH3 binding domain protein 5 like" Q7L8J4 1 248810446-248825915 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 7.7;eosinophil: 4.1;neutrophil: 4.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038067, HPA038068" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA038067: AB_2675814, HPA038068: AB_10670651" "unprognostic (2.48e-1)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (4.41e-1)" "unprognostic (2.78e-1)" "unprognostic (2.27e-3)" "unprognostic (1.99e-3)" "unprognostic (5.84e-2)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (2.87e-3)" "unprognostic (1.50e-2)" "unprognostic (1.13e-1)" "unprognostic (2.05e-2)" "unprognostic (1.55e-1)" "unprognostic (4.99e-2)" "unprognostic (4.66e-2)" 9.6 10.5 18.0 10.1 18.7 9.0 7.7 17.3 21.0 8.8 13.9 12.2 13.5 10.5 7.8 15.8 10.0 8.0 14.1 19.4 15.8 9.5 10.5 9.2 11.3 17.0 16.7 8.6 10.0 12.0 5.9 11.4 16.9 9.1 7.3 5.3 11.9 11.6 30.6 18.4 12.4 9.9 15.8 12.3 9.9 9.5 17.1 13.8 8.1 17.8 10.2 9.0 9.1 18.3 23.2 14.7 18.5 21.2 25.7 17.1 24.6 51.1 17.4 29.2 21.8 14.3 20.0 11.6 29.7 44.1 7.3 24.6 17.9 22.1 15.0 25.4 6.3 18.6 16.4 11.9 15.8 20.4 21.9 14.4 23.4 33.0 12.9 20.7 19.6 21.4 33.0 12.0 20.2 7.9 19.7 16.5 32.4 25.5 36.9 21.9 13.0 23.5 20.5 10.6 21.1 29.2 15.6 19.3 17.9 14.0 21.0 42.4 27.5 36.9 15.7 14.7 80.2 30.5 34.3 10.5 26.8 23.5 15.4 7.7 1.2 4.1 0.7 0.8 0.7 0.6 1.0 0.6 1.1 0.6 0.3 0.3 4.6 0.3 0.3 0.4 0.2 0.8 18.0 18.7 17.3 21.0 19.4 15.8 17.0 16.7 16.9 15.8 17.1 18.3 5.2 0.0 2.0 5.9 4.3 4.6 2.1 2.9 4.0 8.3 6.1 5.0 9.4 1.5 2.3 11.0 0.0 9.6 4.7 15.1 1.9 8.8 1.3 10.5 5.4 6.0 7.7 6.9 6.5 6.0 5.2 4.9 7.7 6.1 0.0 9.0 6.1 10.0 6.0 8.4 5.7 8.4 2.0 5.3 4.5 1.0 4.4 5.6 3.6 3.7 7.1 4.7 6.2 6.0 6.4 10.6 8.1 5.7 5.4 3.0 13.8 9.2 5.1 3.5 0.0 3.7 5.8 8.8 7.0 7.0 4.7 11.4 6.3 5.4 7.3 3.3 SH3RF1 "KIAA1494, POSH, RNF142, SH3MD2" ENSG00000154447 "SH3 domain containing ring finger 1" Q7Z6J0 4 169094259-169270956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 146.3;Oligodendrocytes: 213.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.2;myeloid DC: 2.5;non-classical monocyte: 6.7" "Group enriched" "Detected in many" 15 "dendritic cells: 2.5;monocytes: 6.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074783 Approved Supported "Vesicles,Intermediate filaments" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "Intermediate filaments" "HPA074783: AB_2732268" "unprognostic (4.14e-1)" "unprognostic (4.67e-2)" "unprognostic (1.23e-1)" "unprognostic (7.83e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "unprognostic (1.29e-1)" "unprognostic (2.65e-1)" "unprognostic (8.44e-2)" "unprognostic (9.58e-2)" "unprognostic (4.77e-3)" "unprognostic (7.88e-2)" "prognostic favorable (5.51e-8)" "unprognostic (4.43e-2)" "unprognostic (1.63e-1)" "unprognostic (5.99e-2)" "unprognostic (1.77e-1)" 9.8 3.7 8.7 4.4 10.0 3.4 8.2 7.6 13.1 5.7 5.9 15.1 13.8 4.3 5.7 5.9 5.6 11.9 5.7 18.2 8.6 12.2 8.0 9.4 3.3 8.8 9.7 8.5 10.4 3.7 3.7 7.4 9.4 14.3 13.6 2.4 15.8 8.4 9.4 5.1 13.1 4.0 8.2 3.9 24.7 6.1 9.5 2.0 19.9 10.0 3.2 9.3 4.4 13.0 15.2 12.2 11.0 31.9 11.5 14.3 14.1 40.5 19.7 30.0 13.8 12.5 17.8 0.0 1.9 43.1 8.1 9.8 8.9 16.2 32.4 0.1 5.2 8.7 27.4 6.5 26.0 3.1 0.3 8.5 8.6 25.7 19.9 37.3 18.7 3.3 0.1 0.0 27.8 6.0 3.1 2.9 5.6 19.2 10.5 4.5 3.6 0.6 13.6 11.8 8.3 9.9 10.4 15.7 4.2 4.7 5.2 1.3 17.1 14.2 11.0 23.6 14.7 1.1 0.0 0.1 16.0 3.0 17.3 0.0 1.0 0.0 0.0 4.2 0.0 0.3 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.2 6.7 0.2 0.0 0.6 8.7 10.0 7.6 13.1 18.2 8.6 8.8 9.7 9.4 8.2 9.5 13.0 28.0 64.1 37.7 146.3 3.4 34.3 48.3 11.9 13.6 3.5 21.1 15.6 11.2 44.3 34.4 27.6 0.0 12.7 0.4 69.3 11.7 42.2 5.5 28.5 14.2 13.0 31.3 2.1 54.9 63.7 22.1 16.5 65.7 46.5 10.2 5.6 11.4 12.4 7.4 0.0 54.9 27.1 12.2 9.3 5.3 3.5 12.2 11.1 3.6 52.5 3.9 11.3 0.0 89.5 213.0 68.4 37.2 12.0 2.4 63.2 28.9 18.4 31.7 1.2 65.7 24.1 36.9 5.4 10.7 9.4 12.6 13.1 1.7 6.5 34.4 72.0 SHOX "GCFX, PHOG, SHOXY, SS" ENSG00000185960 "Short stature homeobox" O15266 X 624344-659411 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 7.6" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 2.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "midbrain: 7.6;pons: 7.5" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 4 "BJ: 18.5;BJ hTERT+: 8.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "midbrain: 2.7;thalamus: 3.8" "HPA035141, HPA060931" Enhanced Nucleoplasm,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA035141: AB_2674489, HPA060931: AB_2684388" "unprognostic (7.51e-3)" "unprognostic (1.99e-1)" "unprognostic (3.08e-2)" "unprognostic (2.23e-1)" "unprognostic (4.00e-1)" "unprognostic (6.82e-2)" "unprognostic (2.45e-2)" "unprognostic (2.34e-1)" "unprognostic (9.24e-2)" "unprognostic (9.95e-2)" "unprognostic (5.67e-6)" "unprognostic (1.99e-1)" "unprognostic (1.71e-1)" "unprognostic (9.14e-2)" "unprognostic (1.38e-1)" 0.7 0.4 0.2 0.3 0.3 0.9 0.2 1.4 0.6 0.0 0.0 0.2 0.6 0.1 0.3 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.1 0.3 1.2 7.6 0.1 0.3 0.2 0.0 0.1 7.5 0.3 0.2 0.4 0.6 0.0 1.2 0.4 0.4 0.1 0.1 0.7 0.2 0.1 1.4 0.0 0.3 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.1 0.1 0.2 0.1 3.0 18.5 8.4 2.7 2.9 0.3 0.2 0.2 0.1 0.4 0.7 0.2 0.2 0.0 0.9 0.1 0.1 0.1 1.4 0.1 0.1 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.8 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.0 0.2 0.2 0.0 0.2 0.2 0.0 0.1 0.1 0.1 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.1 0.8 0.0 0.2 0.1 0.1 0.0 2.9 0.6 0.6 0.4 0.3 0.4 0.5 0.3 0.3 0.1 0.7 0.4 0.5 1.7 0.7 0.6 0.6 0.3 0.3 0.2 0.3 1.4 0.6 0.2 0.2 1.2 7.6 7.5 0.1 1.4 1.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 SIM1 bHLHe14 ENSG00000112246 "SIM bHLH transcription factor 1" P81133 6 100385009-100464921 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.4;kidney: 9.9;skeletal muscle: 3.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 20.2;Distal tubular cells: 7.9;Ductal cells: 4.5;Skeletal myocytes: 7.6" "Cancer enhanced" "Detected in single" "renal cancer: 1.8" "Group enriched" "Detected in some" 5 "hypothalamus: 4.4;midbrain: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.7;BJ: 16.4;BJ hTERT+: 23.7;BJ hTERT+ SV40 Large T+: 7.2;HDLM-2: 7.3;RPTEC TERT1: 18.4" "Region enriched" "Detected in single" 8 "hypothalamus: 5.2" "Region enhanced" "Detected in some" "hypothalamus: 3.1" HPA024385 Approved "Nuclear speckles" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "Nuclear speckles" "HPA024385: AB_1856879" "unprognostic (1.04e-1)" "unprognostic (4.34e-3)" "unprognostic (2.24e-1)" "unprognostic (1.51e-1)" "unprognostic (4.34e-1)" "unprognostic (1.38e-1)" "unprognostic (2.85e-1)" "unprognostic (4.64e-2)" "unprognostic (3.76e-2)" "prognostic favorable (5.32e-7)" "unprognostic (1.00e-1)" "unprognostic (1.19e-1)" 1.7 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 4.4 9.9 0.3 0.0 0.0 0.0 1.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.5 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.5 9.7 0.0 16.4 23.7 7.2 6.7 0.0 0.0 0.0 0.0 5.2 1.5 0.0 0.0 0.0 6.1 7.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 18.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 4.4 0.0 1.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 20.2 0.0 0.1 0.0 0.0 7.9 4.5 1.8 0.1 0.1 0.1 1.8 0.0 0.1 1.2 0.1 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 7.6 0.3 1.5 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.1 SLC16A2 "AHDS, DXS128, MCT7, MCT8, MRX22, XPCT" ENSG00000147100 "Solute carrier family 16 member 2" P36021 X 74421493-74533917 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.7" "Cell type enhanced" "Detected in many" "Astrocytes: 22.2;Hepatocytes: 63.7;Inhibitory neurons: 21.6;Oligodendrocyte precursor cells: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 83.9;GAMG: 70.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072719 Approved "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA072719: AB_2686552" "prognostic unfavorable (8.88e-5)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-3)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (1.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" "unprognostic (5.67e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (2.15e-2)" "unprognostic (1.89e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (3.16e-4)" 13.8 24.7 4.6 4.8 5.8 0.0 5.4 1.7 5.7 9.4 1.2 7.0 3.3 10.3 1.7 2.9 9.3 6.0 10.4 7.7 4.9 7.9 40.7 7.5 0.9 5.6 3.9 12.8 5.5 11.7 9.8 9.2 1.8 6.2 1.8 1.1 5.0 5.8 2.7 2.5 3.1 6.9 3.5 1.2 4.7 0.9 8.1 5.7 12.6 3.7 1.8 6.6 6.2 3.0 8.4 10.4 7.2 43.1 20.8 11.1 0.0 83.9 29.7 38.2 20.6 0.1 0.9 0.0 1.3 37.5 70.8 1.7 1.1 40.2 22.1 6.1 3.6 0.0 0.0 0.0 1.5 0.0 0.0 16.5 9.5 19.3 23.3 14.6 0.1 0.1 0.0 0.0 9.1 0.0 0.5 2.7 27.2 0.0 7.8 17.4 19.9 0.0 18.0 0.1 1.9 12.0 9.6 50.2 0.3 2.5 0.6 1.1 0.0 32.5 8.8 35.7 41.9 0.0 0.0 0.0 34.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 1.7 5.7 7.7 4.9 5.6 3.9 1.8 3.5 8.1 3.0 5.6 0.0 0.6 22.2 0.2 0.8 4.3 2.4 0.6 5.7 4.3 3.4 4.5 8.6 2.9 3.7 0.0 5.7 0.1 0.0 3.9 4.3 0.1 0.3 9.8 6.1 8.4 0.0 14.5 2.4 4.9 11.8 0.5 0.5 2.5 1.7 3.6 63.7 1.0 3.3 21.6 0.3 0.0 1.3 0.8 1.2 15.2 0.1 3.6 15.9 0.6 6.2 0.0 23.1 7.1 4.6 0.0 20.7 0.1 5.1 0.4 4.7 2.4 1.5 13.1 9.7 5.6 0.1 0.1 0.9 1.3 2.1 0.4 1.4 0.2 4.9 SLC22A4 "DFNB60, MGC34546, OCTN1" ENSG00000197208 "Solute carrier family 22 member 4" Q9H015 5 132294394-132344190 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.7" "Group enriched" "Detected in many" 5 "Erythroid cells: 57.0;Proximal enterocytes: 25.6;Respiratory ciliated cells: 78.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 36.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 59.1;U-138 MG: 24.4" "Region enhanced" "Detected in all" "cerebellum: 64.5" "Low region specificity" "Detected in all" "CAB015468, HPA036974" Approved Approved Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "CAB015468: , HPA036974: AB_2732474" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (8.42e-3)" "unprognostic (6.17e-2)" "unprognostic (6.22e-3)" "unprognostic (4.17e-3)" "unprognostic (3.33e-1)" "unprognostic (1.30e-1)" "unprognostic (9.79e-2)" "unprognostic (1.95e-3)" "unprognostic (7.82e-2)" "unprognostic (1.74e-2)" "unprognostic (2.31e-3)" "unprognostic (1.20e-1)" "unprognostic (1.95e-2)" "unprognostic (4.06e-2)" 1.9 3.0 2.1 2.9 1.9 20.7 2.2 3.7 1.8 1.5 1.1 2.0 3.5 1.4 1.4 0.4 11.3 1.9 1.9 1.9 3.6 7.1 0.8 2.9 0.3 4.0 3.7 2.1 0.6 2.6 2.6 1.0 3.4 4.0 2.2 2.2 1.7 1.4 7.2 1.3 9.1 1.0 3.6 5.1 1.4 0.6 3.4 0.4 0.7 2.7 0.2 1.4 0.9 2.9 1.9 3.0 0.2 0.7 1.3 1.0 0.9 12.9 59.1 9.7 10.1 1.1 3.3 0.6 3.6 7.6 7.2 3.2 0.0 2.1 6.8 2.6 0.3 0.1 5.6 0.2 1.0 4.1 0.0 2.3 0.4 5.3 4.9 3.5 4.3 0.3 5.3 6.7 7.6 1.1 0.0 9.5 0.3 0.3 3.2 0.0 0.8 0.4 1.5 0.2 0.8 0.4 14.0 0.9 0.4 0.4 0.6 2.4 5.2 24.4 2.4 9.7 3.3 0.0 2.7 0.0 7.2 4.7 2.9 0.0 5.6 5.8 0.0 1.3 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 36.2 0.0 0.4 0.3 0.0 1.2 2.1 1.9 3.7 1.8 1.9 3.6 4.0 3.7 3.4 3.6 3.4 2.9 1.1 3.2 0.0 5.5 0.1 0.8 1.0 3.8 1.8 2.0 1.9 1.3 0.8 1.5 10.0 0.0 0.0 1.0 0.1 8.8 0.0 3.2 0.0 4.7 1.8 3.8 1.2 57.0 7.2 0.4 2.3 3.1 0.5 2.2 0.0 0.6 1.4 0.0 4.0 3.3 8.0 0.8 4.1 0.8 0.8 0.3 0.6 3.7 0.0 1.9 2.2 1.6 0.0 4.5 2.3 1.9 1.7 0.0 0.1 1.7 25.6 8.6 78.5 0.4 0.0 9.3 1.8 0.3 0.4 0.2 0.4 2.5 0.2 0.1 1.0 0.9 SLC38A11 "AVT2, FLJ39822" ENSG00000169507 "Solute carrier family 38 member 11" Q08AI6 2 164896186-164955525 "Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 28.7;epididymis: 38.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 28.6;Enteroendocrine cells: 174.1;Excitatory neurons: 53.4;Sertoli cells: 72.3;Smooth muscle cells: 39.8" "Cancer enriched" "Detected in many" 5 "prostate cancer: 7.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 28 "memory B-cell: 1.6;naive B-cell: 3.9" "Lineage enriched" "Detected in single" 39 "B-cells: 3.9" "Cell line enriched" "Detected in some" 9 "BJ hTERT+: 249.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043432 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA043432: AB_10793948" "unprognostic (1.52e-1)" "unprognostic (2.59e-1)" "unprognostic (4.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" "unprognostic (6.28e-3)" "unprognostic (3.53e-2)" "unprognostic (2.41e-1)" "unprognostic (2.12e-1)" "unprognostic (1.15e-3)" "unprognostic (1.99e-1)" "prognostic favorable (2.00e-8)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "unprognostic (2.43e-2)" "unprognostic (2.36e-2)" 2.0 4.0 6.0 1.5 6.4 0.1 0.8 3.8 11.2 2.6 28.7 1.5 6.0 1.7 38.6 1.0 0.8 17.7 1.3 6.2 3.9 7.9 2.6 0.4 2.0 3.9 4.2 0.3 2.2 1.3 3.3 0.3 4.3 10.8 2.7 0.3 0.6 16.9 0.9 0.6 2.7 2.0 3.5 8.1 11.7 0.2 5.8 0.3 2.1 4.0 1.3 1.5 1.1 6.3 0.0 0.6 0.0 0.0 0.0 0.0 0.1 28.9 249.7 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.1 0.0 5.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.0 6.4 3.8 11.2 6.2 3.9 3.9 4.2 4.3 3.5 5.8 6.3 0.9 0.0 0.0 6.2 7.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.9 28.6 0.0 3.7 0.0 0.7 2.7 0.5 0.0 3.2 2.1 0.1 0.5 2.7 174.1 2.7 53.4 0.6 0.6 0.3 5.1 0.1 0.0 0.0 0.4 3.7 0.0 0.0 2.9 6.4 0.0 0.0 0.3 1.2 0.0 0.0 0.0 17.8 0.0 0.1 0.0 0.5 1.2 0.8 2.3 0.0 0.0 3.2 1.0 2.0 0.0 0.1 72.3 0.5 39.8 0.1 0.0 0.2 0.3 1.5 0.9 4.4 0.7 0.2 SLC8A1 NCX1 ENSG00000183023 "Solute carrier family 8 member A1" P32418 2 40097270-40611053 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 117.5" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 743.1;Excitatory neurons: 1267.5;Inhibitory neurons: 631.3;Microglial cells: 574.3;Oligodendrocyte precursor cells: 753.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.2" "Group enriched" "Detected in many" 6 "granulocytes: 44.2;monocytes: 11.5" "Cell line enhanced" "Detected in many" "BJ: 28.9;fHDF/TERT166: 70.4;hTERT-HME1: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022694, HPA070007" Uncertain Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane" "CAB022694: , HPA070007: AB_2686227" "unprognostic (2.46e-1)" "unprognostic (1.33e-2)" "unprognostic (1.42e-2)" "unprognostic (7.57e-6)" "unprognostic (1.56e-1)" "unprognostic (3.94e-1)" "unprognostic (2.28e-2)" "unprognostic (4.60e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.66e-2)" "unprognostic (7.04e-3)" "unprognostic (3.93e-2)" "unprognostic (5.46e-2)" "unprognostic (6.77e-2)" 6.1 4.0 25.7 7.2 25.8 2.0 1.6 0.0 28.0 4.7 0.0 9.6 5.0 19.7 5.6 5.9 5.6 6.5 117.5 30.6 11.0 17.5 3.1 5.8 3.3 1.5 19.8 2.5 1.8 0.7 0.8 11.2 0.7 18.8 4.8 5.9 1.0 27.1 0.3 1.5 5.5 23.4 2.7 7.3 3.5 0.7 19.5 2.0 0.8 0.9 1.5 8.9 2.5 24.1 3.0 2.2 2.1 0.2 3.1 6.4 0.0 28.9 11.1 9.4 6.1 0.0 4.7 0.1 2.2 70.4 10.1 1.1 0.5 4.8 9.5 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.5 3.7 0.0 10.8 19.8 4.3 0.7 0.0 0.0 0.4 12.1 0.0 0.9 0.1 1.4 0.3 4.0 7.8 14.8 0.0 3.3 0.4 3.2 0.6 0.0 0.0 0.0 9.7 0.1 0.6 9.8 8.8 0.3 0.0 3.1 1.6 0.0 0.0 1.4 1.7 1.4 0.0 8.3 0.0 0.0 9.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 44.2 0.0 11.5 0.3 0.0 1.1 25.7 25.8 0.0 28.0 30.6 11.0 1.5 19.8 0.7 2.7 19.5 24.1 10.3 3.2 2.8 39.5 3.6 1.3 0.0 0.2 1.2 79.1 0.5 5.8 743.1 2.8 0.6 35.0 4.2 0.5 0.3 0.0 0.0 0.0 1.1 2.3 52.8 15.1 0.0 3.0 1267.5 0.0 1.6 26.6 1.5 3.0 0.0 0.2 12.1 0.3 29.3 0.0 631.3 2.5 0.0 78.0 26.7 1.4 0.0 88.8 1.8 574.3 42.7 32.0 1.0 753.0 20.5 0.1 3.8 8.2 0.7 0.2 24.7 0.5 0.0 7.2 13.1 1.4 46.6 0.2 1.2 0.5 3.1 1.1 1.2 0.7 2.5 0.1 SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 256.7;Inhibitory neurons: 544.9;Oligodendrocytes: 157.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.0;BJ hTERT+: 200.8;BJ hTERT+ SV40 Large T+: 97.8;fHDF/TERT166: 117.8;HBF TERT88: 112.0;HEK 293: 88.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" 8.0 24.9 3.2 3.3 6.4 0.0 9.4 0.0 14.0 24.0 11.7 11.5 2.4 16.4 9.9 5.8 13.1 9.4 7.8 6.6 20.5 12.3 2.0 34.9 1.8 7.9 3.1 4.3 2.8 1.5 8.8 25.2 4.5 12.6 5.4 13.2 6.1 15.7 2.9 3.8 4.8 24.9 0.4 14.2 9.0 1.3 17.6 2.4 9.2 5.1 1.2 13.1 13.9 2.4 0.1 0.0 54.6 0.0 37.8 34.8 1.7 98.0 200.8 97.8 36.9 0.4 0.1 0.0 3.4 117.8 0.2 1.2 15.7 7.9 112.0 0.2 88.3 0.0 0.4 0.0 7.2 0.9 0.0 8.5 0.0 63.6 18.6 2.1 35.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 1.7 0.0 6.3 61.2 0.5 0.0 1.0 0.1 3.5 0.8 0.0 0.2 0.4 1.9 0.2 0.2 2.0 34.9 5.0 35.0 54.2 0.0 0.1 0.0 0.9 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 6.4 0.0 14.0 6.6 20.5 7.9 3.1 4.5 0.4 17.6 2.4 1.6 0.0 9.0 10.1 0.0 8.0 2.0 0.1 0.6 47.6 1.0 0.6 5.2 1.5 1.3 0.0 0.0 1.1 0.0 0.6 1.9 1.7 0.6 6.4 1.9 2.0 1.2 0.0 256.7 0.5 1.2 58.8 0.0 7.1 2.5 1.3 4.2 0.2 1.9 0.0 544.9 0.0 0.0 1.0 9.7 1.7 26.4 0.7 8.8 31.9 0.0 1.3 0.0 43.7 157.9 0.2 0.0 26.7 0.1 3.7 0.0 11.5 7.4 2.1 6.6 3.2 6.4 0.2 1.7 1.2 6.7 2.1 1.1 20.3 0.1 1.9 SMAD4 "DPC4, MADH4" ENSG00000141646 "SMAD family member 4" Q13485 18 51028394-51085045 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019154 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" Centrosome "HPA019154: AB_1853480" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (4.83e-2)" "unprognostic (1.17e-2)" "unprognostic (4.05e-1)" "unprognostic (7.29e-3)" "unprognostic (9.00e-2)" "unprognostic (4.01e-2)" "unprognostic (2.51e-2)" "unprognostic (1.03e-3)" "unprognostic (4.40e-2)" "prognostic favorable (1.92e-5)" "unprognostic (2.62e-2)" "unprognostic (4.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" 16.4 11.8 9.0 10.9 10.3 10.6 17.2 21.7 10.5 18.5 11.2 14.9 11.9 20.6 9.8 15.7 16.3 12.8 14.1 11.7 10.0 16.1 19.1 13.1 12.7 9.0 8.2 24.0 21.4 19.9 11.3 18.9 9.4 21.8 14.3 18.3 14.0 18.0 24.9 14.6 12.1 18.9 8.0 13.9 15.2 14.2 11.9 17.7 21.4 24.9 14.5 13.5 13.1 13.8 16.4 22.5 59.4 16.6 23.9 36.6 31.4 27.7 32.2 39.4 49.6 13.0 3.8 25.9 7.8 25.6 19.6 24.9 33.6 13.2 40.7 19.3 14.8 20.6 20.5 15.9 23.7 34.8 13.1 16.6 21.9 19.1 27.8 37.0 28.7 14.0 21.9 25.8 23.5 9.0 18.8 10.0 31.2 9.1 14.3 23.3 30.6 26.9 18.2 7.4 34.4 20.3 27.0 5.0 18.8 24.8 13.3 19.4 20.0 34.5 13.3 8.8 19.7 30.6 28.6 26.2 21.2 12.8 22.6 0.3 0.6 0.6 1.0 0.4 1.1 0.7 1.0 0.8 1.2 0.9 1.2 1.5 1.0 1.0 0.4 1.0 1.4 0.5 9.0 10.3 21.7 10.5 11.7 10.0 9.0 8.2 9.4 8.0 11.9 13.8 32.5 22.4 29.1 55.2 21.0 25.6 20.9 15.1 18.8 17.1 27.3 20.4 38.8 24.3 19.3 22.0 20.9 20.7 24.0 22.7 11.7 16.9 10.6 30.4 36.6 26.2 39.6 12.4 37.0 12.5 20.6 30.3 28.5 35.2 4.5 132.4 28.5 44.1 15.1 15.2 39.0 32.1 16.2 28.5 20.9 16.2 33.2 21.1 28.4 49.6 16.9 20.4 17.5 41.2 72.5 20.1 21.0 30.5 24.8 36.3 26.7 22.6 22.4 20.0 26.3 32.2 34.2 17.2 18.8 20.9 27.3 12.6 20.1 22.1 24.5 29.7 SMG9 "C19orf61, FLJ12886" ENSG00000105771 "SMG9 nonsense mediated mRNA decay factor" Q9H0W8 19 43727983-43754962 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 103.2;Late spermatids: 329.5;Syncytiotrophoblasts: 95.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041763, HPA042096" Uncertain Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" "Plasma membrane" "HPA041763: AB_2677659, HPA042096: AB_2677845" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (7.41e-2)" "unprognostic (6.46e-2)" "unprognostic (2.71e-1)" "unprognostic (1.55e-2)" "prognostic unfavorable (2.15e-5)" "unprognostic (2.71e-1)" "unprognostic (4.11e-2)" "unprognostic (9.24e-3)" "unprognostic (3.88e-2)" "unprognostic (8.76e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (8.00e-2)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "prognostic favorable (8.09e-4)" 9.0 11.7 10.3 10.9 10.8 8.4 8.7 10.9 13.5 10.6 5.9 9.0 8.0 9.0 7.7 9.2 7.7 6.8 7.7 10.2 10.6 7.7 6.6 10.0 13.0 13.1 11.6 7.8 5.8 8.8 9.4 10.1 13.6 11.5 6.2 5.9 12.0 6.9 7.5 10.7 10.0 8.1 9.5 13.5 8.7 33.8 11.6 11.8 8.3 7.1 12.0 10.0 9.9 14.9 25.3 27.2 19.5 12.5 13.4 18.9 13.1 35.1 20.8 38.4 28.7 19.4 32.5 27.4 16.9 24.1 13.2 10.7 22.9 19.7 24.9 21.1 13.2 49.2 20.5 12.9 15.6 37.4 25.9 10.1 16.6 27.9 29.6 32.1 15.8 25.0 37.7 23.6 18.0 17.9 39.9 10.6 9.4 48.0 18.2 21.2 16.1 12.3 20.4 20.4 32.4 15.9 36.7 27.4 21.3 15.4 16.6 20.5 19.2 59.7 35.4 22.3 27.1 11.5 26.8 33.4 17.9 28.4 49.7 1.0 5.3 3.3 5.1 7.7 4.5 7.4 5.1 4.3 6.9 5.3 6.7 4.5 1.3 4.2 11.7 6.1 4.1 11.3 10.3 10.8 10.9 13.5 10.2 10.6 13.1 11.6 13.6 9.5 11.6 14.9 7.7 32.1 8.3 20.9 13.7 9.3 15.0 16.8 11.4 13.2 10.0 11.0 4.4 4.3 9.0 9.2 4.2 49.5 11.3 9.5 1.9 12.2 103.2 5.5 7.0 12.0 4.2 7.8 19.5 8.7 15.8 11.4 15.8 8.9 9.5 12.1 11.0 3.3 21.4 13.5 23.0 11.3 8.2 10.3 9.2 329.5 13.1 12.1 10.6 11.2 16.2 6.0 4.1 16.1 29.6 13.6 9.2 12.0 11.2 15.9 8.5 6.8 8.4 9.2 6.6 11.2 8.5 42.6 16.2 8.4 7.1 95.4 9.3 11.8 12.2 11.1 SMURF2 ENSG00000108854 "SMAD specific E3 ubiquitin protein ligase 2" Q9HAU4 17 64542282-64662307 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ: 221.1;HBF TERT88: 157.4;LHCN-M2: 164.1;TIME: 207.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071508 Enhanced Supported "Nuclear speckles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA071508: AB_2686406" "unprognostic (1.21e-1)" "unprognostic (2.07e-2)" "unprognostic (1.59e-2)" "unprognostic (3.24e-1)" "unprognostic (6.19e-2)" "unprognostic (7.33e-2)" "unprognostic (2.67e-2)" "unprognostic (1.50e-1)" "unprognostic (7.94e-2)" "unprognostic (1.09e-2)" "unprognostic (5.46e-3)" "unprognostic (2.54e-1)" "unprognostic (5.55e-2)" "unprognostic (1.98e-2)" "unprognostic (7.82e-2)" "unprognostic (2.20e-2)" "unprognostic (1.41e-1)" 6.8 4.3 3.3 6.2 3.9 5.9 5.2 5.3 3.4 7.3 3.4 5.3 6.9 5.9 2.3 4.4 5.8 7.1 4.1 3.1 3.3 7.0 3.8 10.5 5.0 4.6 2.7 4.8 6.5 6.3 3.4 13.3 2.8 7.4 4.8 12.5 6.2 5.2 3.0 5.0 10.1 6.1 3.2 5.4 7.8 13.0 3.6 7.8 8.3 6.2 6.5 7.5 3.2 3.8 67.0 17.8 15.3 9.1 11.0 41.5 7.6 221.1 103.2 88.2 73.4 10.4 45.5 8.6 14.5 38.8 29.9 15.2 16.0 37.2 157.4 4.3 12.9 9.1 10.9 11.8 12.0 12.2 5.5 11.8 16.1 109.5 48.5 52.7 97.0 11.9 13.0 7.5 164.1 13.2 28.3 4.8 9.9 8.8 23.8 6.1 38.4 5.2 20.1 11.1 16.0 17.9 14.4 5.8 10.0 24.6 11.7 8.4 207.6 93.8 44.4 39.2 139.6 10.4 11.7 13.9 23.7 7.3 28.4 1.0 0.6 1.4 1.0 0.4 1.1 0.7 0.8 1.1 0.7 0.9 0.9 0.9 1.4 2.7 0.3 0.6 0.2 0.5 3.3 3.9 5.3 3.4 3.1 3.3 4.6 2.7 2.8 3.2 3.6 3.8 40.2 32.1 26.0 96.3 18.6 43.8 30.8 10.0 25.0 26.4 23.3 18.7 10.3 7.2 16.1 9.2 43.8 13.2 35.4 13.8 9.8 18.1 29.0 29.0 37.2 39.3 17.9 2.5 46.1 10.0 3.6 28.1 12.2 39.7 13.3 21.4 38.2 5.1 13.6 26.9 40.9 11.2 10.2 17.3 25.5 9.2 12.5 22.8 21.4 101.2 13.2 21.4 20.6 101.0 52.8 26.5 24.7 12.0 18.0 25.2 28.0 9.6 14.4 46.7 0.0 37.4 23.3 37.1 21.3 13.7 39.8 7.3 33.5 16.2 13.8 24.6 SOCS5 "CIS6, Cish5, CISH6, KIAA0671, SOCS-5" ENSG00000171150 "Suppressor of cytokine signaling 5" O75159 2 46698952-46780245 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ hTERT+: 121.0;fHDF/TERT166: 121.9;U-138 MG: 80.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020884, CAB025510" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "CAB025510: , HPA020884: AB_1857356" "unprognostic (1.69e-1)" "unprognostic (1.98e-2)" "unprognostic (5.71e-2)" "unprognostic (1.64e-2)" "unprognostic (2.20e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.28e-4)" "unprognostic (4.52e-2)" "unprognostic (9.13e-2)" "prognostic unfavorable (7.53e-4)" "unprognostic (2.10e-3)" "unprognostic (3.01e-1)" "unprognostic (1.47e-3)" "unprognostic (8.29e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" 12.0 10.2 7.6 6.3 7.7 7.7 13.0 15.9 9.6 13.0 7.5 9.7 5.2 14.1 9.1 8.5 9.3 11.3 11.3 8.1 7.6 9.2 6.7 8.7 6.7 8.3 8.3 23.2 6.2 14.2 5.6 7.3 8.5 9.9 6.6 12.7 8.7 12.4 9.0 7.5 6.7 13.9 8.5 9.0 6.6 10.3 8.2 7.6 9.9 16.0 6.7 9.3 8.5 8.6 14.5 10.8 9.3 13.8 29.9 42.3 11.4 66.5 121.0 31.5 18.6 10.3 6.9 7.5 12.7 121.9 9.7 7.1 9.9 10.8 41.2 7.3 9.4 11.8 10.0 13.2 18.4 6.9 12.7 33.9 15.8 26.7 10.7 35.8 11.0 3.0 10.2 8.1 21.5 5.3 5.9 12.0 10.4 15.1 8.7 7.8 15.9 9.5 13.2 11.1 7.3 19.8 16.4 10.7 13.0 8.9 4.4 10.3 12.8 80.0 17.7 26.9 13.2 9.7 6.4 6.5 36.9 13.7 25.5 0.5 0.4 2.5 0.9 0.4 1.1 1.8 0.5 0.6 0.5 3.0 1.1 1.5 0.4 1.0 1.7 0.5 1.0 0.7 7.6 7.7 15.9 9.6 8.1 7.6 8.3 8.3 8.5 8.5 8.2 8.6 17.2 3.2 6.1 18.9 11.3 16.6 7.2 8.3 16.5 12.8 15.1 12.2 14.2 18.6 8.0 3.7 22.9 3.7 6.2 11.0 5.9 7.3 12.3 9.9 29.2 24.3 10.8 6.1 43.4 6.8 2.5 18.8 10.2 12.0 17.1 17.4 17.2 7.9 4.5 18.5 51.5 7.1 2.0 8.4 15.2 8.1 17.4 7.7 7.2 18.7 8.4 9.7 6.2 38.2 25.4 6.8 8.8 17.0 7.0 11.0 5.1 7.3 5.3 5.5 13.1 13.8 20.1 13.3 18.8 9.9 14.5 2.7 7.0 7.3 5.6 7.8 SOCS6 "CIS4, Cish4, HSPC060, SOCS4, SSI4, STAI4, STATI4" ENSG00000170677 "Suppressor of cytokine signaling 6" O14544 18 70289045-70330199 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.6;myeloid DC: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010189 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Cytosol "CAB010189: AB_661195" "unprognostic (1.76e-3)" "unprognostic (6.83e-3)" "unprognostic (8.90e-3)" "unprognostic (4.52e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-1)" "unprognostic (2.07e-1)" "unprognostic (7.93e-2)" "unprognostic (5.83e-2)" "unprognostic (1.75e-1)" "unprognostic (6.90e-2)" "unprognostic (8.19e-2)" "prognostic favorable (1.02e-4)" "unprognostic (1.02e-1)" "unprognostic (1.52e-1)" "unprognostic (4.11e-2)" "unprognostic (1.80e-2)" 7.9 8.0 8.3 6.0 10.2 13.1 14.0 11.7 8.1 15.2 5.8 16.2 15.6 11.8 6.9 15.0 12.3 13.5 11.0 7.8 7.6 9.3 28.3 9.7 3.4 14.8 10.2 10.9 13.0 14.1 4.1 13.9 14.4 8.4 14.4 5.6 11.3 7.9 12.8 7.1 22.8 10.9 13.2 4.1 14.0 5.7 17.5 3.2 11.6 13.4 5.6 8.3 8.0 19.3 19.2 41.6 17.4 12.0 16.1 18.9 19.4 40.3 24.5 24.0 18.0 15.6 31.7 2.1 3.6 37.7 29.0 22.2 12.8 13.2 23.3 0.0 7.8 14.4 14.3 24.1 19.1 7.9 15.6 15.3 15.4 20.9 17.4 23.9 12.2 1.7 8.7 9.6 16.5 9.3 6.8 5.8 11.2 12.2 17.7 8.0 16.8 3.5 14.9 15.6 8.0 20.0 20.9 22.8 18.9 12.4 6.8 13.6 15.1 26.3 13.3 5.5 16.5 0.0 0.0 5.2 29.3 0.6 18.1 0.0 3.6 2.9 0.2 0.7 0.1 0.3 0.4 0.0 3.9 0.0 0.6 0.3 0.0 1.0 0.0 0.3 0.0 1.2 8.3 10.2 11.7 8.1 7.8 7.6 14.8 10.2 14.4 13.2 17.5 19.3 15.0 25.6 17.0 8.1 1.2 11.7 13.7 13.3 12.0 12.9 26.6 14.7 22.4 21.5 30.1 11.0 6.2 28.0 2.1 61.0 11.7 18.4 1.3 23.5 23.5 13.9 29.4 3.8 17.0 18.5 15.6 13.7 21.4 34.6 31.0 9.1 13.6 32.4 25.7 37.0 17.5 31.0 10.2 7.7 11.1 2.8 11.5 19.2 26.6 86.2 10.1 7.8 5.2 28.6 32.1 30.5 30.5 12.8 0.9 17.4 36.8 25.6 21.8 4.7 0.0 14.9 12.5 1.3 11.0 20.5 11.9 68.4 2.1 4.4 26.7 34.6 SOGA1 "C20orf117, dJ132F21.1, FLJ44670, KIAA0889, SOGA" ENSG00000149639 "Suppressor of glucose, autophagy associated 1" O94964 20 36777447-36863538 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 63.9" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 54.8;Oligodendrocytes: 50.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043992 Approved Approved Nucleoli,Cytosol "Secreted to blood" NA Yes "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli, Cytosol" "HPA043992: AB_2678762" "unprognostic (2.34e-2)" "unprognostic (1.35e-1)" "unprognostic (6.58e-2)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.48e-1)" "unprognostic (2.27e-3)" "unprognostic (1.37e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (1.09e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (4.49e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (4.45e-3)" 6.6 14.2 13.4 3.6 18.1 1.1 6.2 63.9 16.4 9.5 0.0 12.3 1.9 10.9 3.8 7.0 9.6 4.8 9.5 12.8 14.4 7.8 0.9 6.2 2.5 14.6 15.0 10.4 2.8 7.3 4.9 6.2 12.6 9.0 2.8 4.5 4.7 8.8 2.4 8.6 5.8 8.4 8.8 4.6 6.4 7.9 15.1 2.9 12.2 3.9 3.1 11.2 7.4 21.9 13.4 18.0 21.5 23.2 12.2 11.2 5.6 11.6 12.5 16.1 9.5 7.3 2.1 6.0 4.2 20.4 14.0 17.8 17.3 10.8 16.8 0.9 3.4 9.7 18.5 9.7 6.4 2.1 9.0 6.3 13.0 15.4 10.9 7.0 10.6 6.5 6.9 1.2 17.8 13.0 6.9 5.1 5.5 1.3 13.8 16.1 19.9 2.3 9.5 4.0 25.5 15.9 24.1 26.1 7.5 9.4 33.3 14.4 16.3 40.2 7.7 19.9 25.7 2.4 0.6 5.8 17.1 2.8 26.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 13.4 18.1 63.9 16.4 12.8 14.4 14.6 15.0 12.6 8.8 15.1 21.9 16.5 0.0 1.8 18.9 4.4 12.6 5.4 6.3 13.6 26.3 9.6 8.9 16.1 5.7 6.7 20.2 37.5 15.6 11.3 1.7 1.9 3.8 0.9 8.6 20.5 14.5 6.0 1.3 19.9 1.5 10.2 12.0 0.5 21.9 10.8 33.0 10.4 0.6 10.0 23.5 30.3 1.5 0.0 7.6 10.7 2.4 12.2 8.1 5.4 21.5 4.5 17.8 0.0 54.8 50.9 1.4 2.4 18.8 1.8 6.0 2.1 1.5 3.9 3.8 13.1 23.2 16.9 0.5 1.3 13.7 16.1 3.3 1.4 14.0 3.0 2.9 SPDL1 "CCDC99, FLJ20364, hSpindly" ENSG00000040275 "Spindle apparatus coiled-coil protein 1" Q96EA4 5 169583636-169604778 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.5" "Cell type enhanced" "Detected in many" "Granulosa cells: 38.4;Spermatocytes: 112.9;Spermatogonia: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA044700, HPA048146" Enhanced Approved Cytosol NA Yes "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA044700: AB_2679052, HPA048146: AB_2680284" "unprognostic (2.61e-2)" "unprognostic (1.94e-1)" "unprognostic (8.59e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (4.24e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.48e-6)" "unprognostic (2.63e-3)" "unprognostic (5.70e-3)" "unprognostic (8.27e-3)" "prognostic unfavorable (1.19e-5)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.81e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.93e-1)" 3.9 3.6 5.5 9.4 6.0 10.9 5.5 6.1 7.2 3.4 3.4 5.4 5.7 6.2 3.8 5.8 4.4 4.5 3.4 4.7 5.6 4.8 3.2 4.0 14.9 6.0 5.5 6.7 2.5 5.0 2.4 8.4 6.1 3.3 5.7 3.4 3.2 3.1 5.3 5.5 5.3 7.4 7.1 6.6 5.3 35.5 5.4 21.5 4.3 5.9 14.0 4.8 3.8 7.2 57.0 69.2 67.4 47.6 17.6 18.5 59.1 181.1 22.9 128.1 119.0 89.6 38.8 54.3 116.9 147.0 90.3 39.3 56.8 76.0 139.6 58.1 65.2 59.6 117.0 36.2 8.3 66.9 51.3 9.2 6.2 62.2 34.0 29.0 59.9 60.5 41.3 39.3 142.4 58.5 54.1 28.2 50.1 28.9 63.2 64.8 67.6 38.5 89.7 19.8 43.7 31.4 84.9 23.6 34.5 46.9 27.0 44.9 46.3 146.6 46.8 43.4 140.0 30.1 69.2 69.1 35.4 61.9 50.2 4.0 2.7 3.8 8.4 3.6 8.9 11.2 7.9 8.9 2.8 12.7 10.8 9.1 0.5 8.4 6.2 19.7 8.6 4.1 5.5 6.0 6.1 7.2 4.7 5.6 6.0 5.5 6.1 7.1 5.4 7.2 6.1 3.2 6.3 3.9 8.7 4.0 1.7 4.8 4.6 6.9 6.2 7.5 7.1 2.8 7.0 1.8 0.0 14.1 9.8 3.6 5.9 6.6 9.6 5.3 8.0 6.5 1.8 22.3 6.2 4.8 26.1 7.7 12.2 4.9 8.8 38.4 13.2 3.2 12.2 3.3 6.5 3.2 2.0 4.7 3.6 11.1 4.4 4.7 3.6 2.8 5.0 7.4 13.4 5.0 6.8 6.6 1.9 6.4 10.2 1.6 0.5 8.2 4.1 4.4 6.6 6.4 9.9 112.9 59.2 5.8 4.4 4.9 5.2 9.6 7.4 2.5 SPECC1L "CYTSA, KIAA0376" ENSG00000100014 "Sperm antigen with calponin homology and coiled-coil domains 1 like" Q69YQ0 22 24270817-24417739 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA070614 Uncertain Supported "Actin filaments" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Actin filaments" "HPA070614: AB_2686287" "unprognostic (3.54e-1)" "unprognostic (4.93e-3)" "unprognostic (1.62e-1)" "unprognostic (5.88e-2)" "unprognostic (3.74e-2)" "unprognostic (1.28e-1)" "unprognostic (2.54e-1)" "unprognostic (7.82e-3)" "unprognostic (4.98e-2)" "unprognostic (1.72e-3)" "prognostic favorable (7.92e-4)" "unprognostic (3.15e-3)" "unprognostic (6.20e-3)" "unprognostic (1.40e-1)" "unprognostic (3.71e-1)" "unprognostic (5.79e-3)" "unprognostic (1.41e-1)" 13.0 13.1 12.3 12.4 12.8 13.3 13.8 34.0 13.5 16.6 17.7 15.8 7.8 15.9 9.7 17.5 15.5 12.5 18.6 10.8 15.7 14.6 14.4 17.2 12.5 18.1 16.2 22.0 13.3 17.3 14.6 10.1 18.9 20.1 16.9 10.7 16.2 15.1 12.7 9.2 11.6 19.0 15.8 11.1 11.5 31.9 16.6 14.5 24.0 13.1 13.8 14.9 13.0 13.7 31.1 22.8 42.9 23.7 40.1 39.2 14.5 43.1 34.1 36.8 36.4 25.5 8.4 44.9 10.3 39.5 29.0 27.0 39.2 24.2 43.4 26.1 21.1 28.5 12.9 23.4 26.7 51.2 27.0 33.1 19.2 32.8 34.2 28.8 44.0 18.9 24.5 19.0 39.3 17.3 26.6 18.5 20.7 22.5 17.1 24.0 43.3 16.1 18.4 23.3 37.2 38.3 36.5 27.5 23.8 37.1 18.3 14.4 46.3 77.2 43.7 19.3 29.3 22.7 23.4 20.0 22.6 19.0 29.2 3.9 2.4 4.8 3.3 3.5 2.5 2.8 2.2 1.6 2.3 3.1 2.7 2.9 3.2 1.3 1.6 3.7 1.6 1.9 12.3 12.8 34.0 13.5 10.8 15.7 18.1 16.2 18.9 15.8 16.6 13.7 11.6 16.0 21.3 0.0 10.4 3.6 2.7 5.0 10.2 8.4 13.8 9.4 13.7 14.3 9.1 12.9 10.4 7.3 7.9 32.8 1.9 6.7 26.9 8.3 14.9 12.0 14.4 7.6 0.0 7.4 3.2 11.4 8.2 9.8 16.5 13.4 15.7 11.4 7.3 10.1 0.0 12.2 14.2 7.3 2.2 93.7 16.1 6.9 14.2 0.0 14.8 6.4 9.2 0.0 0.0 9.0 15.0 13.5 10.7 5.7 8.9 6.1 11.9 8.5 13.1 11.3 12.5 24.1 28.5 9.8 3.1 5.9 9.3 7.6 8.0 3.8 SPG21 "ABHD21, ACP33, BM-019, GL010, MAST" ENSG00000090487 "SPG21 abhydrolase domain containing, maspardin" Q9NZD8 15 64963022-64990310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 181.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040407, HPA040436" Approved Supported Vesicles,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA040407: AB_2676965, HPA040436: AB_10796454" "unprognostic (7.47e-2)" "unprognostic (2.94e-2)" "unprognostic (5.81e-2)" "unprognostic (2.98e-1)" "unprognostic (1.64e-1)" "unprognostic (5.40e-3)" "unprognostic (7.25e-2)" "unprognostic (1.43e-1)" "unprognostic (4.19e-2)" "unprognostic (8.07e-2)" "unprognostic (4.24e-3)" "unprognostic (1.15e-1)" "unprognostic (3.96e-1)" "unprognostic (1.55e-1)" "unprognostic (3.49e-1)" "unprognostic (2.57e-1)" "unprognostic (3.19e-1)" 56.6 61.7 48.4 50.8 54.1 69.4 68.8 51.5 52.9 60.4 66.0 61.6 52.1 60.2 150.1 46.1 73.4 54.7 54.4 47.8 50.3 85.3 113.1 61.9 56.9 52.1 50.2 55.3 54.7 72.1 47.1 66.3 52.7 49.8 59.3 38.6 45.7 59.0 74.3 58.5 46.6 64.5 51.1 52.6 60.1 35.0 52.6 57.7 83.1 42.4 58.8 61.2 47.8 59.4 87.0 127.0 62.8 119.5 158.7 155.7 78.0 52.8 179.7 103.2 119.8 57.4 131.1 99.1 80.6 124.8 153.1 113.3 182.1 124.5 97.8 41.0 58.5 85.7 81.7 104.0 200.7 82.2 72.7 107.0 139.3 82.1 154.2 100.7 125.6 112.2 72.7 78.3 127.8 124.1 75.8 71.5 69.6 193.9 66.3 78.2 67.3 174.6 107.1 103.6 76.7 68.6 62.7 131.4 124.9 123.3 89.9 140.9 61.5 87.1 90.6 125.4 80.6 55.6 101.8 58.2 112.8 215.1 75.1 9.9 138.2 15.5 14.1 84.2 13.1 39.0 13.8 14.7 76.9 37.6 19.9 10.9 181.4 15.7 69.8 25.1 17.5 52.3 48.4 54.1 51.5 52.9 47.8 50.3 52.1 50.2 52.7 51.1 52.6 59.4 29.4 9.6 56.3 11.1 67.7 74.9 81.8 70.6 66.6 16.2 62.7 39.4 32.1 61.5 51.5 71.7 37.5 202.9 33.6 42.7 137.0 97.1 6.0 32.9 36.9 56.9 64.8 54.3 13.1 74.1 92.2 67.5 46.9 34.3 28.5 37.5 38.2 121.6 153.9 20.2 13.7 58.2 61.1 158.7 145.4 13.2 86.6 128.5 80.0 16.9 123.2 24.8 64.9 5.5 19.6 62.3 93.5 89.9 66.2 145.2 121.1 202.3 57.9 18.9 39.5 93.4 39.5 35.4 51.3 75.4 82.8 186.5 46.5 35.5 69.5 123.5 SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 105.4;Muller glia cells: 165.1;Pancreatic endocrine cells: 101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 127.6;TIME: 108.9;U-251 MG: 142.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "olfactory bulb: 5.7" "HPA022829, HPA028761" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA022829: AB_1857438, HPA028761: AB_10600814" "unprognostic (1.04e-1)" "unprognostic (6.30e-2)" "unprognostic (1.09e-2)" "unprognostic (8.66e-2)" "unprognostic (2.25e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (9.32e-3)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (8.99e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.14e-6)" "unprognostic (1.39e-1)" "unprognostic (4.82e-2)" "unprognostic (8.29e-2)" "unprognostic (1.10e-3)" 18.9 4.1 4.0 10.5 3.0 17.3 18.0 2.1 3.9 11.0 2.3 7.0 1.9 6.7 3.9 23.8 9.4 11.9 17.5 2.9 3.9 21.4 3.8 24.3 8.1 4.0 4.1 4.3 14.4 4.8 4.9 2.5 4.5 7.3 1.1 8.4 19.9 1.5 3.2 15.6 7.0 3.2 2.3 5.0 6.7 5.8 8.5 3.5 10.6 0.8 4.1 11.3 13.1 3.9 36.9 3.7 15.2 0.8 7.6 7.0 15.8 82.6 54.0 67.8 40.8 19.4 3.9 1.8 7.4 61.0 28.9 7.7 11.7 105.4 16.4 1.6 6.2 0.5 28.3 127.6 16.6 1.3 2.9 13.6 2.1 105.9 41.3 28.8 66.0 3.7 17.3 0.2 13.5 46.6 3.5 0.6 0.9 8.2 29.7 2.5 4.1 2.8 3.7 0.5 2.0 3.6 8.3 0.9 74.4 9.1 3.0 5.1 108.9 105.8 20.8 82.3 142.1 1.7 0.4 1.6 80.5 6.5 16.1 1.5 1.9 0.0 0.7 0.9 0.2 0.0 0.1 0.2 0.5 0.1 0.0 0.1 0.2 0.0 0.2 4.8 0.0 0.8 4.0 3.0 2.1 3.9 2.9 3.9 4.0 4.1 4.5 2.3 8.5 3.9 22.0 0.0 0.0 1.0 2.8 12.6 57.0 18.6 2.8 1.5 31.1 29.1 5.3 47.1 6.6 1.8 0.0 1.2 9.1 1.0 0.0 105.4 0.2 15.3 13.5 51.2 0.0 22.3 0.5 12.7 16.9 27.5 3.1 60.7 7.0 0.4 4.2 0.2 30.1 33.7 1.6 2.4 6.1 8.9 45.4 1.4 3.7 39.9 12.4 1.0 61.5 165.1 3.1 0.0 0.1 101.8 1.2 19.9 3.5 68.9 0.8 2.5 2.0 3.9 0.0 17.3 54.3 0.0 9.5 6.7 10.7 1.4 4.2 0.8 0.4 27.0 SPHKAP SKIP ENSG00000153820 "SPHK1 interactor, AKAP domain containing" Q2M3C7 2 227979955-228181687 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "brain: 78.3;heart muscle: 29.1" "Group enriched" "Detected in some" 8 "Cardiomyocytes: 82.2;Excitatory neurons: 67.7;Granulosa cells: 33.6;Inhibitory neurons: 128.6" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "cerebellum: 78.3;cerebral cortex: 49.3;hippocampal formation: 41.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "BJ hTERT+: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042499, HPA048168" Enhanced NA NA "Cluster 6: Brain - Smell perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042499: AB_2678027, HPA048168: AB_2680296" "unprognostic (4.91e-3)" "unprognostic (6.46e-2)" "unprognostic (1.33e-1)" "unprognostic (2.59e-2)" "unprognostic (2.95e-2)" "unprognostic (2.09e-1)" "unprognostic (1.01e-3)" 0.0 0.1 10.6 0.0 8.8 0.0 0.8 78.3 49.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.1 41.1 4.2 0.0 0.0 0.1 0.0 6.8 13.3 2.1 0.0 0.0 0.0 0.0 7.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.2 11.2 0.3 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 45.9 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 8.8 78.3 49.3 41.1 4.2 6.8 13.3 7.1 4.2 11.2 3.3 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 7.2 2.6 3.0 82.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 67.7 0.0 0.0 2.1 0.0 0.0 0.0 33.6 0.0 0.0 0.0 0.0 128.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 9.5 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 SPOCD1 "FLJ25348, PPP1R146" ENSG00000134668 "SPOC domain containing 1" Q6ZMY3 1 31790422-31816051 "Predicted intracellular proteins" "Differentiation, RNA-mediated gene silencing, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;testis: 9.7;urinary bladder: 9.5" "Cell type enhanced" "Detected in some" "Hofbauer cells: 13.2;Pancreatic endocrine cells: 30.9;Smooth muscle cells: 10.4;Spermatogonia: 13.1;Urothelial cells: 48.6" "Group enriched" "Detected in many" 7 "glioma: 13.9;urothelial cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 49.9;hTEC/SVTERT24-B: 51.5;RT4: 89.2;TIME: 46.2;U-87 MG: 84.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031713, HPA031714, HPA031715" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Nucleoplasm, Nucleoli" "HPA031713: AB_10604099, HPA031714: AB_2674007, HPA031715: AB_2674008" "unprognostic (7.78e-2)" "unprognostic (2.58e-2)" "unprognostic (1.85e-3)" "unprognostic (2.70e-3)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (2.15e-3)" "unprognostic (2.60e-2)" "unprognostic (3.51e-1)" "unprognostic (2.18e-1)" "unprognostic (3.01e-2)" "unprognostic (3.00e-1)" "unprognostic (0.00e+0)" "unprognostic (1.97e-1)" "unprognostic (1.06e-1)" "unprognostic (1.54e-2)" "prognostic favorable (4.05e-5)" 3.0 0.4 1.1 3.1 1.8 0.1 1.6 1.1 4.0 3.0 2.5 0.4 0.9 2.2 0.3 0.3 1.1 0.9 0.2 1.2 1.8 0.5 0.1 7.3 0.1 7.6 2.9 0.3 0.0 0.0 1.5 0.3 4.2 1.6 0.5 0.0 0.3 0.1 0.1 0.3 0.9 1.4 1.6 1.9 0.9 9.7 11.8 0.2 0.3 0.0 0.0 9.5 0.9 3.1 29.8 0.8 0.1 0.1 0.5 4.0 1.4 37.7 49.9 35.8 23.7 0.5 1.7 0.5 5.0 42.7 14.7 3.9 0.0 0.7 11.2 0.1 0.1 0.0 5.8 0.2 1.7 0.0 0.6 17.7 0.6 51.5 1.7 28.9 24.4 2.0 0.7 0.6 21.5 0.1 0.2 0.0 0.7 0.4 0.8 0.0 3.8 0.0 0.1 89.2 0.0 0.0 0.9 0.2 2.6 1.2 21.6 0.0 46.2 37.4 3.9 24.6 14.3 0.2 0.3 0.1 84.6 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.1 1.1 1.8 1.1 4.0 1.2 1.8 7.6 2.9 4.2 1.6 11.8 3.1 0.2 0.0 3.7 0.3 0.0 0.1 6.5 4.5 0.0 0.0 0.3 0.1 0.5 0.0 1.7 0.0 0.0 0.2 0.0 0.0 0.0 8.3 0.3 1.7 0.6 2.3 1.8 0.0 0.4 9.8 0.6 1.0 0.0 5.9 1.3 0.2 0.4 0.0 13.2 0.0 0.1 0.0 0.0 0.6 0.2 0.5 0.0 5.7 0.0 0.0 0.1 0.0 0.0 0.0 1.6 30.9 0.0 0.4 0.1 2.5 0.0 0.1 0.3 0.0 0.0 5.1 10.4 0.0 13.1 0.0 0.0 0.3 0.4 0.1 0.0 48.6 SSTR1 ENSG00000139874 "Somatostatin receptor 1" P30872 14 38207904-38213067 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0;intestine: 13.8;stomach 1: 21.7" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 18.1;Gastric mucus-secreting cells: 16.8;Hepatic stellate cells: 27.1;Oligodendrocyte precursor cells: 24.1;Paneth cells: 10.7;Proximal enterocytes: 11.8" "Cancer enhanced" "Detected in many" "prostate cancer: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 118.9;BJ hTERT+: 32.5;BJ hTERT+ SV40 Large T+: 21.4;fHDF/TERT166: 70.7;HeLa: 26.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003207, HPA031506" Approved Uncertain Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA003207: , HPA031506: AB_2673913" "unprognostic (1.40e-1)" "unprognostic (1.37e-1)" "unprognostic (3.36e-1)" "unprognostic (2.50e-3)" "unprognostic (4.34e-2)" "unprognostic (9.90e-2)" "unprognostic (3.66e-3)" "unprognostic (1.91e-1)" "unprognostic (6.16e-3)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (9.19e-2)" "prognostic favorable (4.28e-4)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" "unprognostic (3.28e-2)" 1.0 0.3 3.9 0.3 8.8 0.0 0.9 0.5 8.7 0.8 0.0 3.5 13.8 1.0 0.4 0.3 0.9 0.4 1.0 10.0 10.0 2.0 6.8 5.2 0.0 4.7 7.0 0.8 3.6 0.0 0.9 2.6 5.6 1.0 2.3 0.3 0.3 0.4 0.7 0.3 8.2 0.5 1.4 0.6 21.7 0.1 6.1 0.0 0.3 0.9 0.0 1.8 0.7 1.7 0.0 0.0 0.0 0.0 0.3 0.2 0.0 118.9 32.5 21.4 1.8 1.2 0.0 0.0 0.0 70.7 0.0 0.2 0.0 0.0 15.4 0.0 0.0 0.0 26.7 0.1 6.3 0.0 0.0 0.2 0.0 0.0 0.3 0.4 1.5 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.1 9.6 0.2 0.0 0.0 0.1 4.7 0.0 3.4 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 8.8 0.5 8.7 10.0 10.0 4.7 7.0 5.6 1.4 6.1 1.7 1.7 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 1.5 0.2 0.0 0.8 2.8 0.0 1.8 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 2.4 18.1 0.0 3.9 0.8 0.0 1.0 16.8 0.0 0.0 0.0 27.1 7.2 0.0 0.0 5.5 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 24.1 0.3 0.2 10.7 0.0 0.1 0.1 11.8 1.9 0.0 0.1 0.0 1.0 0.6 0.0 0.1 0.1 0.1 0.1 0.0 0.2 6.2 0.0 ST6GALNAC5 "MGC3184, SIAT7E, ST6GalNAcV" ENSG00000117069 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5" Q9BVH7 1 76867480-77067546 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 480.3;Inhibitory neurons: 417.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.9" "Region enhanced" "Detected in many" "cerebral cortex: 5.9;hippocampal formation: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.7;fHDF/TERT166: 5.4;HaCaT: 2.7;SH-SY5Y: 4.1;U-2 OS: 4.4;U-251 MG: 2.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 51.3" "HPA065593, HPA070354" Uncertain Approved Vesicles "Intracellular and membrane" NA Yes 180000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA065593: AB_2685515, HPA070354: AB_2686260" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (1.72e-1)" "unprognostic (1.49e-2)" "unprognostic (2.82e-2)" "unprognostic (2.04e-2)" "unprognostic (4.67e-2)" "unprognostic (2.72e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-1)" "unprognostic (1.61e-2)" "unprognostic (1.58e-1)" "unprognostic (2.10e-2)" "unprognostic (5.90e-3)" "unprognostic (9.66e-2)" "unprognostic (6.88e-2)" "unprognostic (1.69e-2)" 0.1 3.0 1.5 1.5 1.1 0.0 1.2 0.0 5.9 0.7 0.0 1.8 0.2 0.1 0.0 1.0 1.9 2.2 0.5 5.5 0.0 0.1 0.0 3.6 0.4 0.0 0.0 1.6 0.1 0.0 1.9 0.1 0.0 1.0 0.6 3.2 0.5 0.3 0.0 0.2 0.9 3.0 0.0 0.2 1.5 0.3 0.0 0.0 0.0 0.0 0.3 1.6 0.6 0.0 1.2 0.0 4.7 0.0 0.0 0.0 0.0 0.4 1.5 1.1 0.4 0.0 0.1 0.0 0.0 5.4 0.0 2.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.3 0.4 0.0 0.0 1.1 4.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 4.4 0.0 2.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 5.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.5 0.5 35.6 0.1 0.0 0.0 0.1 0.0 20.7 2.8 1.7 1.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.2 1.9 0.4 0.0 0.0 480.3 0.0 0.1 0.8 0.0 0.2 1.3 0.9 0.0 0.0 0.1 0.0 417.3 0.2 0.0 0.0 0.0 2.3 0.6 0.1 0.0 8.4 0.0 0.7 0.0 10.6 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 1.3 0.0 0.2 0.4 0.1 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.1 STAG1 "SA-1, SA1, SCC3A" ENSG00000118007 "Stromal antigen 1" Q8WVM7 3 136336236-136752403 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 166.8;Microglial cells: 231.4;Oligodendrocyte precursor cells: 223.2;Oligodendrocytes: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035015, HPA058653" Supported Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA035015: AB_10603117, HPA058653: AB_2683787" "unprognostic (1.82e-1)" "unprognostic (1.11e-2)" "unprognostic (1.41e-1)" "unprognostic (5.37e-2)" "unprognostic (4.05e-2)" "unprognostic (1.92e-1)" "unprognostic (4.62e-2)" "unprognostic (5.26e-2)" "unprognostic (1.74e-1)" "unprognostic (7.22e-3)" "unprognostic (1.29e-2)" "unprognostic (1.71e-1)" "unprognostic (5.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.58e-1)" "unprognostic (5.97e-2)" "unprognostic (2.83e-2)" 13.7 9.1 7.6 12.3 8.8 15.7 15.6 17.0 8.3 16.9 9.9 13.5 9.6 19.3 10.6 10.8 13.5 10.3 10.5 6.5 8.7 12.0 10.8 11.2 14.7 9.3 7.8 21.9 12.4 13.7 5.0 17.6 9.0 10.8 14.4 13.2 11.6 12.1 15.0 13.7 11.0 16.1 8.8 11.8 10.0 8.9 7.8 22.5 15.8 15.8 15.9 12.0 11.5 11.2 34.6 17.6 29.1 25.1 21.5 36.8 15.7 37.9 48.4 35.0 33.0 30.2 14.9 26.9 23.3 39.7 28.1 23.4 31.6 17.3 47.4 33.2 14.9 28.8 25.1 16.7 16.3 50.6 27.7 23.4 19.3 25.6 28.6 20.3 27.5 28.8 18.7 52.7 22.3 29.5 33.6 16.4 19.0 23.7 13.9 29.6 31.6 35.7 19.1 24.5 14.2 22.8 40.8 16.0 17.5 15.0 22.9 21.2 23.3 40.1 29.0 36.0 33.9 39.1 28.9 59.5 24.6 17.0 26.2 4.0 3.0 4.6 4.4 3.0 4.6 6.4 3.7 4.0 2.8 4.4 4.1 3.3 8.7 5.5 3.5 4.5 4.8 2.1 7.6 8.8 17.0 8.3 6.5 8.7 9.3 7.8 9.0 8.8 7.8 11.2 44.5 25.6 24.2 95.6 42.4 40.0 31.4 18.7 38.7 43.8 24.8 26.7 10.8 22.8 23.5 16.5 39.6 29.3 39.5 42.1 11.7 20.7 2.8 23.7 59.5 34.1 18.7 29.7 161.8 22.2 26.7 33.8 23.9 39.6 22.2 30.3 31.4 21.5 18.6 28.6 166.8 27.9 8.2 16.9 22.0 4.8 49.4 25.1 16.0 231.4 27.2 25.6 42.2 223.2 188.4 27.4 17.5 32.4 53.1 27.2 24.2 13.2 14.5 68.1 26.3 67.1 36.2 54.8 50.5 27.5 36.7 31.7 39.2 16.0 23.4 24.3 STAMBPL1 "ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2, FLJ31524, KIAA1373" ENSG00000138134 "STAM binding protein like 1" Q96FJ0 10 88879734-88975153 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.8" "Cell type enhanced" "Detected in many" "Early spermatids: 54.3;Excitatory neurons: 60.5;Microglial cells: 32.8;Spermatocytes: 40.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040202 Uncertain Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA040202: AB_10805708" "unprognostic (2.73e-1)" "unprognostic (1.95e-1)" "unprognostic (7.56e-2)" "unprognostic (4.25e-2)" "unprognostic (6.46e-2)" "unprognostic (6.27e-2)" "unprognostic (1.68e-2)" "unprognostic (1.05e-2)" "unprognostic (4.67e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.08e-5)" "unprognostic (4.41e-2)" "unprognostic (4.06e-2)" "unprognostic (1.50e-1)" "unprognostic (4.40e-3)" 3.9 23.8 5.5 10.4 6.5 5.3 2.5 2.6 9.0 2.7 0.0 8.7 6.4 4.2 0.9 4.4 2.2 4.1 8.0 6.2 1.4 1.8 1.8 3.6 16.2 1.1 0.5 12.7 2.3 3.4 5.5 1.2 2.6 1.7 9.7 4.4 1.4 1.1 0.7 3.7 7.3 3.0 1.9 7.2 5.1 18.0 0.5 7.1 1.2 1.5 12.2 6.4 2.5 5.6 14.8 16.5 1.0 0.6 14.4 27.7 0.0 31.5 28.9 19.0 16.3 0.3 25.6 18.6 2.3 15.6 12.3 6.4 4.1 4.5 17.9 16.3 10.8 4.6 10.4 0.9 10.3 20.2 5.7 10.6 1.4 31.6 9.6 18.4 0.6 20.9 0.0 7.3 50.0 3.0 34.2 21.5 6.6 13.3 14.1 3.4 13.0 3.8 6.5 4.7 9.6 11.9 3.7 1.1 37.5 3.6 2.3 4.1 4.9 17.0 12.4 20.7 19.9 17.7 19.7 17.2 18.2 19.4 16.9 9.5 1.0 8.1 10.7 1.1 14.1 17.7 15.5 13.7 1.7 14.9 16.6 10.0 1.4 23.6 0.5 27.9 28.3 8.0 5.5 6.5 2.6 9.0 6.2 1.4 1.1 0.5 2.6 1.9 0.5 5.6 2.3 0.0 4.5 10.7 16.7 9.6 5.3 1.4 1.2 3.6 2.3 1.4 8.6 0.0 0.2 5.5 0.0 0.1 18.8 7.6 0.0 1.3 54.3 1.9 6.5 1.8 9.1 3.4 60.5 1.8 0.1 7.7 3.1 1.4 5.1 7.4 1.8 2.4 3.7 6.7 26.2 9.3 4.1 1.3 9.6 20.7 7.2 3.1 0.0 32.8 1.0 9.3 12.3 26.2 1.9 1.9 2.8 1.5 14.2 1.9 7.9 0.8 5.0 0.4 0.0 20.4 6.4 40.2 2.5 5.9 11.4 0.1 17.6 14.9 14.2 2.9 STX12 "STX13, STX14" ENSG00000117758 "Syntaxin 12" Q86Y82 1 27773219-27824443 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041038, HPA055300" Approved Enhanced "Nucleoplasm,Golgi apparatus,Vesicles" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA041038: AB_10794261, HPA055300: AB_2682778" "unprognostic (3.47e-1)" "unprognostic (1.27e-1)" "unprognostic (1.60e-1)" "unprognostic (8.16e-3)" "unprognostic (2.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.26e-2)" "unprognostic (3.52e-1)" "unprognostic (1.14e-2)" "unprognostic (2.78e-2)" "unprognostic (9.35e-2)" "unprognostic (3.55e-1)" "unprognostic (1.91e-2)" "unprognostic (8.43e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "unprognostic (2.24e-1)" 64.2 30.1 38.1 26.6 39.0 10.8 37.0 40.8 45.6 28.8 25.4 30.7 36.3 30.9 62.9 39.2 23.9 39.8 20.9 37.3 41.7 35.2 29.1 50.0 25.6 42.0 45.3 22.1 30.3 46.5 26.6 33.3 43.6 30.7 32.5 43.2 26.9 32.1 21.4 27.0 32.8 35.9 42.2 30.5 65.5 13.4 38.4 17.3 94.7 27.1 22.2 39.1 23.4 44.6 23.2 10.9 28.8 19.0 53.9 65.0 14.8 47.9 70.3 43.1 48.5 13.5 29.5 25.2 49.6 64.6 18.5 19.0 19.2 23.9 42.9 22.2 22.8 14.4 12.0 13.7 42.2 16.1 29.0 61.3 28.7 60.6 34.5 35.3 70.3 14.3 19.1 24.6 47.7 8.5 13.7 12.3 12.1 34.3 15.3 8.7 23.1 15.5 38.1 37.5 32.3 17.6 22.4 19.3 35.2 23.3 13.1 14.0 76.2 21.9 12.5 50.0 16.6 14.5 11.2 14.3 35.1 24.1 31.2 24.6 35.7 13.7 6.1 39.4 10.6 13.6 7.3 9.7 25.2 10.8 8.1 6.8 16.5 9.2 40.6 12.4 7.9 17.4 38.1 39.0 40.8 45.6 37.3 41.7 42.0 45.3 43.6 42.2 38.4 44.6 93.0 54.5 36.3 25.1 43.6 109.4 97.2 30.7 51.2 46.2 42.0 25.7 18.9 30.0 40.8 57.0 31.3 30.0 28.3 82.8 37.2 51.9 2.0 34.7 33.1 71.1 41.3 17.7 70.9 58.4 33.5 53.2 108.6 49.4 22.8 26.7 47.8 20.4 50.6 26.9 65.7 29.5 14.2 91.4 77.7 4.2 36.1 62.3 53.4 56.2 41.3 67.9 36.0 34.7 59.1 68.4 58.6 47.4 33.9 74.9 51.3 69.7 27.4 51.2 39.5 45.7 57.5 20.0 20.1 69.9 99.2 78.0 31.6 54.0 29.9 99.9 STX1B "STX1B1, STX1B2" ENSG00000099365 "Syntaxin 1B" P61266 16 30989256-31010638 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 137.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 36.8;Horizontal cells: 38.7;Inhibitory neurons: 31.1;Late spermatids: 13.8" "Cancer enriched" "Detected in some" 7 "glioma: 5.1" "Region enhanced" "Detected in many" "cerebral cortex: 137.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 9.0;hTEC/SVTERT24-B: 11.1;hTERT-RPE1: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079008" Supported Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "Nuclear membrane" "CAB079008: , HPA069176: AB_2686098" "unprognostic (1.43e-3)" "unprognostic (5.27e-2)" "unprognostic (2.40e-4)" "unprognostic (3.90e-3)" "unprognostic (3.98e-2)" "unprognostic (1.90e-2)" "unprognostic (2.21e-3)" "unprognostic (2.53e-2)" "unprognostic (1.72e-1)" "unprognostic (3.72e-3)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (1.02e-3)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (7.93e-2)" "unprognostic (1.57e-2)" 1.5 1.0 7.0 1.1 13.1 0.4 1.7 20.0 137.2 1.7 0.0 2.5 0.5 3.0 3.3 1.2 1.7 0.3 1.6 15.9 5.2 1.3 5.9 0.5 1.7 51.2 5.5 1.7 0.9 0.2 6.5 0.2 42.9 1.7 0.4 10.2 1.0 1.8 0.5 3.3 1.8 1.6 0.0 1.8 0.9 4.6 5.8 0.5 0.7 0.1 1.5 0.7 1.3 52.8 0.1 3.0 4.7 0.7 0.5 0.2 0.1 4.2 6.4 5.1 9.0 0.0 3.4 0.7 0.2 5.6 0.1 0.7 2.1 0.6 6.1 2.6 0.4 0.4 2.7 2.4 0.4 0.2 2.9 1.6 0.1 11.1 1.0 20.4 0.0 1.0 0.5 0.2 5.5 1.3 2.0 0.2 2.3 0.0 0.3 7.1 0.2 0.2 0.4 0.0 6.3 4.0 0.5 0.2 0.0 0.7 0.8 0.1 0.8 3.0 2.4 0.4 0.2 0.3 0.2 0.3 3.3 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 13.1 20.0 137.2 15.9 5.2 51.2 5.5 42.9 0.0 5.8 52.8 0.4 0.0 0.0 7.2 0.6 0.8 0.1 0.2 0.6 10.7 0.4 0.6 1.2 0.0 0.0 0.0 2.1 0.0 0.2 0.1 0.0 0.3 6.9 0.1 0.5 0.8 0.0 0.4 36.8 0.4 0.0 0.7 0.0 0.1 0.0 2.5 1.1 5.9 0.6 38.7 31.1 0.2 0.0 0.6 1.1 13.8 0.3 0.3 0.0 4.7 0.7 1.8 0.0 9.0 5.5 0.2 0.0 1.9 0.0 0.2 0.9 2.1 0.0 3.2 0.0 0.8 0.7 4.6 1.3 0.2 0.6 0.8 0.4 0.1 0.3 0.0 STX2 "EPIM, EPM, STX2A, STX2B, STX2C" ENSG00000111450 "Syntaxin 2" P32856 12 130789600-130839266 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 152.2;Endometrial ciliated cells: 86.4;Late spermatids: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079007" Uncertain Supported Approved "Nuclear membrane,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Vesicles "Nuclear membrane" "CAB079007: , HPA069176: AB_2686098" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (8.29e-2)" "unprognostic (2.22e-1)" "unprognostic (3.38e-2)" "unprognostic (9.85e-2)" "unprognostic (2.11e-2)" "unprognostic (4.16e-2)" "unprognostic (2.83e-1)" "unprognostic (7.62e-2)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.15e-5)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.63e-2)" "unprognostic (3.41e-3)" 17.7 11.0 11.2 9.1 11.7 6.4 12.0 12.3 13.4 15.1 24.7 21.2 4.2 14.3 9.8 6.0 16.3 9.9 17.0 12.2 12.1 14.4 13.3 17.8 8.6 15.5 12.3 15.3 10.9 5.9 14.6 13.2 14.5 8.4 6.8 16.7 5.0 10.6 6.7 5.1 11.4 17.2 13.0 12.4 11.4 17.0 11.8 6.9 12.4 7.9 6.2 14.5 10.7 16.3 9.6 18.3 26.8 22.4 27.8 63.2 2.8 44.2 35.8 50.8 35.7 5.5 6.6 11.7 6.6 50.5 16.4 2.8 24.4 6.6 54.9 18.7 9.2 6.4 15.9 15.7 30.6 9.2 15.5 23.4 8.3 24.9 20.1 48.2 27.6 12.7 25.7 11.2 46.2 5.6 13.3 10.6 17.9 2.9 28.2 13.7 18.9 7.0 28.7 2.1 24.3 25.4 20.4 1.8 18.1 23.4 6.1 6.4 36.5 30.1 20.3 33.1 19.6 8.1 6.7 7.9 35.0 10.8 24.4 1.0 0.4 0.6 0.5 0.5 0.5 0.5 0.6 0.5 0.3 0.3 0.6 0.6 0.4 0.2 0.2 0.3 0.4 0.2 11.2 11.7 12.3 13.4 12.2 12.1 15.5 12.3 14.5 13.0 11.8 16.3 35.3 22.4 14.8 20.5 6.2 3.4 1.2 2.1 3.4 5.6 2.1 3.0 17.2 11.5 6.9 29.5 0.0 1.8 12.3 0.4 9.8 19.1 152.2 86.4 40.0 22.4 6.7 32.4 33.6 7.4 7.1 26.5 2.6 7.6 1.3 10.9 17.9 19.0 11.5 0.0 17.6 0.7 2.0 11.5 12.3 114.4 28.0 15.1 14.2 23.4 10.3 12.3 6.2 15.1 24.3 14.5 0.1 24.5 10.2 2.0 0.1 17.6 33.9 31.4 13.1 26.1 29.6 42.0 34.2 1.7 1.4 0.8 14.2 11.7 0.6 0.5 STXBP6 "amisyn, HSPC156" ENSG00000168952 "Syntaxin binding protein 6" Q8NFX7 14 24809656-25050297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 128.6;Inhibitory neurons: 180.6;Oligodendrocytes: 188.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 48.6;Daudi: 50.7;HBF TERT88: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003552, HPA074869" Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA003552: AB_10603343, HPA074869: " "unprognostic (1.52e-1)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (1.20e-2)" "unprognostic (9.01e-2)" "unprognostic (2.28e-2)" "unprognostic (1.05e-1)" "unprognostic (2.37e-2)" "unprognostic (1.69e-1)" "unprognostic (6.46e-3)" "unprognostic (1.51e-1)" "unprognostic (6.73e-3)" "unprognostic (5.10e-3)" "unprognostic (1.16e-1)" "unprognostic (1.43e-1)" "unprognostic (1.36e-1)" "unprognostic (1.48e-3)" 7.3 0.8 18.5 3.8 19.6 0.2 5.0 16.2 27.7 13.5 0.6 11.9 12.3 7.5 38.1 6.0 7.0 11.0 24.7 18.9 21.6 3.6 4.3 26.3 1.6 23.9 23.6 2.8 39.5 23.0 1.0 42.8 17.8 12.7 14.8 2.1 15.0 9.5 4.4 15.0 18.5 5.1 11.4 0.7 9.8 4.4 42.1 7.8 18.0 7.6 5.5 12.3 2.6 19.1 0.1 1.0 2.0 0.5 12.9 22.3 0.2 15.1 40.2 35.5 37.5 48.6 0.3 50.7 0.1 42.6 0.0 0.1 0.0 0.1 64.1 27.2 3.2 12.1 0.4 37.0 9.4 0.9 6.3 3.3 0.0 0.0 0.2 2.0 0.0 1.4 0.5 16.9 34.2 9.7 0.2 0.1 6.6 25.4 0.0 0.0 28.1 0.4 0.0 2.8 2.3 0.1 0.1 7.8 42.6 4.3 0.5 0.7 0.0 6.4 17.2 41.2 2.1 5.1 6.0 2.4 21.8 0.3 24.2 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.2 18.5 19.6 16.2 27.7 18.9 21.6 23.9 23.6 17.8 11.4 42.1 19.1 50.3 51.3 7.7 128.6 0.4 67.7 48.4 0.1 20.5 0.6 2.9 3.3 27.4 64.3 3.4 20.2 0.0 1.4 1.7 12.6 0.0 47.9 20.4 38.8 4.9 35.8 40.7 8.6 72.9 98.7 1.5 44.9 20.4 72.8 42.6 0.8 36.8 5.8 20.1 0.0 180.6 64.6 2.0 1.0 11.0 4.6 1.5 2.9 110.3 113.4 2.0 2.7 0.0 113.6 188.1 39.9 49.6 1.2 3.1 73.9 71.8 9.6 0.0 0.5 0.0 16.4 6.5 12.6 19.7 4.1 48.2 4.0 3.2 0.0 51.7 16.4 SULF1 "hSulf-1, KIAA1077, SULF-1" ENSG00000137573 "Sulfatase 1" Q8IWU6 8 69466624-69660915 "Predicted intracellular proteins" Apoptosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 180.3" "Cell type enhanced" "Detected in many" "Early spermatids: 214.2;Fibroblasts: 52.8;Inhibitory neurons: 63.0;Late spermatids: 101.4;Muller glia cells: 162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 315.4;BJ hTERT+: 420.2;fHDF/TERT166: 520.0;U-2197: 126.1;WM-115: 175.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054728 Supported "Intracellular and membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "HPA054728: AB_2682586" "unprognostic (2.89e-2)" "unprognostic (5.07e-2)" "unprognostic (3.87e-2)" "unprognostic (5.30e-2)" "unprognostic (3.60e-2)" "unprognostic (7.62e-2)" "unprognostic (3.77e-2)" "unprognostic (2.93e-2)" "unprognostic (3.58e-1)" "unprognostic (1.45e-1)" "unprognostic (3.69e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (8.91e-3)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (2.69e-2)" 24.1 2.6 8.1 24.4 6.4 0.0 8.0 2.2 2.7 14.5 180.3 36.4 10.0 28.7 14.2 18.3 11.3 30.6 14.2 6.4 7.4 9.9 1.8 9.7 6.3 1.9 18.2 14.2 3.5 1.4 9.7 4.2 5.8 50.8 20.6 60.0 4.3 41.9 2.2 2.6 14.1 72.6 3.4 2.2 4.0 2.2 18.6 2.2 19.9 11.2 4.8 32.1 9.5 3.0 0.0 0.0 57.3 0.0 6.2 27.3 0.4 315.4 420.2 10.9 1.7 0.0 1.2 0.5 0.2 520.0 0.0 0.4 0.8 0.5 2.1 0.0 1.1 0.0 1.0 0.0 1.5 0.1 0.5 35.6 3.7 18.2 6.7 15.2 1.4 0.0 0.0 0.6 8.5 1.3 0.0 0.0 6.5 0.0 0.4 0.0 23.2 0.9 0.0 0.0 1.1 0.0 0.0 0.5 0.0 22.6 76.7 0.0 0.0 29.0 0.8 126.1 0.0 0.1 0.0 0.1 0.1 0.1 175.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 6.4 2.2 2.7 6.4 7.4 1.9 18.2 5.8 3.4 18.6 3.0 10.6 9.6 6.2 3.9 0.1 0.9 2.7 7.8 26.2 1.8 1.3 13.7 4.3 2.8 13.5 5.5 0.0 0.3 0.0 0.0 0.0 0.3 214.2 1.0 30.5 13.5 1.2 2.7 9.6 0.0 0.0 52.8 0.0 1.0 0.0 0.1 15.4 0.5 0.3 0.0 63.0 0.3 0.0 0.6 1.3 101.4 6.5 0.8 0.0 1.0 0.0 162.8 0.0 3.5 0.6 0.7 0.1 1.9 0.0 1.4 0.0 0.1 5.5 6.5 0.0 5.2 42.4 1.6 1.4 2.5 0.3 0.3 0.3 0.1 0.0 0.4 SURF4 "ERV29, FLJ22993, MGC102753" ENSG00000148248 "Surfeit 4" O15260 9 133361450-133376166 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 325.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064613 Approved Supported "Nuclear membrane,Endoplasmic reticulum,Golgi apparatus,Cytosol" NA Yes 65000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA064613: AB_2685299" "prognostic unfavorable (5.85e-4)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.47e-5)" "prognostic unfavorable (8.11e-4)" "unprognostic (1.10e-3)" "unprognostic (3.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.30e-3)" "unprognostic (1.23e-1)" "unprognostic (9.76e-3)" "unprognostic (7.58e-3)" "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (4.29e-3)" 97.0 106.4 20.3 38.8 22.5 66.5 76.5 22.1 23.4 70.5 27.9 72.1 79.2 78.5 40.6 77.6 71.1 39.0 74.1 21.5 22.3 67.1 223.8 84.2 29.6 23.6 22.2 61.0 150.4 35.4 88.6 55.4 22.2 69.2 37.9 14.0 86.4 39.5 60.1 63.2 82.2 43.4 22.9 59.6 88.5 49.4 25.8 27.8 68.2 23.3 31.4 62.7 59.4 25.9 59.8 96.4 65.3 90.3 134.8 140.2 127.4 184.1 178.4 127.0 124.7 145.9 84.8 41.1 70.6 254.2 122.9 152.7 75.7 94.4 97.0 86.5 46.3 72.1 87.1 156.5 156.2 124.8 94.1 150.4 85.8 109.3 120.2 101.6 118.6 62.9 89.0 109.8 164.5 131.8 60.1 115.4 72.7 162.8 96.2 41.2 89.9 156.5 100.4 56.3 53.8 65.5 136.4 100.4 95.2 61.5 106.6 75.8 127.5 179.4 64.5 137.3 119.6 56.1 86.4 46.4 166.7 66.6 137.5 43.9 40.8 36.2 51.9 32.8 56.9 15.1 36.3 48.4 32.9 12.1 22.0 34.6 28.4 29.4 31.7 38.9 46.9 68.8 20.3 22.5 22.1 23.4 21.5 22.3 23.6 22.2 22.2 22.9 25.8 25.9 53.5 44.8 48.1 18.9 43.0 60.8 65.8 72.5 46.1 21.9 55.5 43.2 42.6 31.5 47.5 35.0 39.6 167.9 80.4 106.9 19.6 95.7 38.6 28.6 72.8 54.8 75.2 31.1 23.2 118.1 254.4 84.8 78.5 67.7 24.7 49.5 47.5 207.3 85.9 33.7 15.6 107.9 30.5 52.3 50.5 19.7 68.3 50.8 40.9 17.8 53.7 53.3 52.5 22.6 23.8 115.1 65.5 53.0 114.8 106.8 151.3 48.5 23.2 26.9 78.9 51.9 80.6 84.4 47.3 46.1 62.4 325.2 90.5 81.8 81.2 84.2 SYDE1 "7h3, FLJ13511, SYD1" ENSG00000105137 "Synapse defective Rho GTPase homolog 1" Q6ZW31 19 15107401-15114985 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 140.3;Peritubular cells: 42.2;Sertoli cells: 85.5;Syncytiotrophoblasts: 134.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 107.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013328 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA013328: AB_1848705" "unprognostic (9.99e-2)" "unprognostic (3.73e-2)" "unprognostic (8.17e-3)" "unprognostic (1.65e-2)" "unprognostic (6.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.07e-2)" "unprognostic (2.46e-2)" "unprognostic (2.96e-1)" "unprognostic (5.01e-3)" "unprognostic (1.43e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (5.63e-7)" "unprognostic (1.82e-2)" "unprognostic (7.57e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.27e-4)" 23.3 12.6 7.8 5.7 8.0 0.0 17.6 7.4 7.8 27.6 15.7 28.6 3.8 32.9 4.6 6.6 23.2 5.7 20.8 6.9 7.2 16.3 4.9 18.1 3.5 9.7 8.0 23.5 6.0 2.5 6.7 15.4 7.9 18.2 2.5 1.4 6.1 11.5 5.4 8.6 11.7 10.8 7.8 12.9 13.5 4.7 8.5 0.9 12.4 3.8 1.4 23.9 18.8 7.3 11.2 17.4 9.0 23.9 19.9 18.2 7.1 46.9 33.7 44.4 37.5 4.1 7.0 0.0 30.3 46.5 15.2 7.0 7.0 8.1 24.6 0.3 8.0 1.6 34.2 7.6 37.7 0.1 0.1 32.1 5.9 26.6 12.0 26.8 8.2 0.0 0.0 0.1 33.6 5.9 0.0 0.0 14.7 0.3 17.3 0.0 22.4 0.2 11.1 1.8 0.3 17.8 25.9 15.9 31.6 8.7 1.9 1.2 17.5 107.3 32.8 49.6 50.4 0.1 0.3 0.2 29.3 0.1 46.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 8.0 7.4 7.8 6.9 7.2 9.7 8.0 7.9 7.8 8.5 7.3 18.6 3.2 1.1 3.6 0.2 2.4 0.8 1.2 1.8 0.3 0.9 3.2 4.1 1.5 0.8 1.8 0.0 7.6 0.0 0.0 0.0 4.7 10.0 0.7 13.6 15.2 0.0 0.0 0.0 0.4 140.3 16.2 0.0 0.5 0.0 12.8 20.0 0.3 3.4 1.7 0.0 0.0 0.0 1.0 2.7 19.3 29.5 0.6 14.2 6.5 0.0 20.0 0.0 1.0 0.2 1.7 0.0 42.2 0.0 0.5 0.0 6.1 0.1 0.8 85.5 10.7 30.8 3.1 0.6 0.3 2.6 134.5 0.4 7.5 0.0 0.2 SYNC "SYNC1, SYNCOILIN" ENSG00000162520 "Syncoilin, intermediate filament protein" Q9H7C4 1 32679906-32703596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 106.8;smooth muscle: 54.1;tongue: 73.4" "Cell type enhanced" "Detected in many" "Horizontal cells: 74.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 121.0;U-138 MG: 113.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA028311, HPA063549" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA028311: AB_2672554, HPA063549: " "unprognostic (3.99e-1)" "unprognostic (6.04e-3)" "unprognostic (2.02e-2)" "unprognostic (7.60e-3)" "unprognostic (1.99e-2)" "unprognostic (5.07e-2)" "unprognostic (5.05e-2)" "unprognostic (5.44e-3)" "unprognostic (1.71e-1)" "unprognostic (1.79e-2)" "unprognostic (5.04e-2)" "unprognostic (3.71e-1)" "unprognostic (1.32e-4)" "unprognostic (1.56e-2)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (8.15e-4)" 10.5 8.5 6.4 15.6 6.1 0.7 5.4 6.7 6.6 9.7 6.1 11.6 6.5 10.9 4.9 17.9 7.4 9.5 17.3 5.8 7.9 2.4 2.2 10.5 6.4 8.3 8.7 3.7 2.6 4.7 0.7 2.5 7.9 13.1 8.7 0.4 9.6 14.6 106.8 2.5 7.3 54.1 9.0 6.2 9.0 9.7 7.4 1.1 4.5 73.4 1.7 12.3 2.9 8.2 8.7 7.0 11.2 19.3 19.4 30.5 6.6 41.9 81.5 28.7 19.6 1.2 24.8 23.9 13.0 121.0 43.4 5.8 1.0 0.7 16.2 12.4 0.8 26.1 22.6 18.0 16.4 33.0 12.0 46.6 2.9 31.6 1.1 86.1 9.0 17.2 19.6 26.2 24.3 4.2 32.0 8.9 5.9 11.2 9.6 34.5 36.5 12.7 32.6 14.2 18.1 1.7 57.1 17.6 21.7 22.2 16.0 10.4 14.4 113.0 19.4 69.4 18.8 11.4 21.1 30.2 39.0 10.4 98.3 5.9 7.7 6.1 6.1 9.6 8.1 6.9 6.9 6.4 9.7 5.2 6.2 7.0 0.9 9.1 9.5 12.3 7.9 12.0 6.4 6.1 6.7 6.6 5.8 7.9 8.3 8.7 7.9 9.0 7.4 8.2 10.6 9.6 9.8 15.7 15.1 22.0 14.2 14.5 8.0 50.2 20.6 7.0 1.0 20.0 14.1 9.2 39.6 9.4 20.7 8.3 5.9 11.7 11.2 12.9 25.0 13.1 7.3 16.0 12.2 5.4 9.3 17.1 0.5 16.3 22.2 12.4 22.9 19.1 5.4 74.0 13.2 8.4 8.2 17.7 23.2 14.8 41.7 7.3 33.8 7.5 11.4 20.0 34.0 15.1 11.6 7.9 7.9 64.3 5.7 16.0 10.7 10.1 6.0 53.9 19.7 16.6 12.8 32.8 36.0 7.2 22.3 5.1 15.3 9.4 12.6 9.4 SYT14 "FLJ34198, sytXIV" ENSG00000143469 "Synaptotagmin 14" Q8NB59 1 209900923-210171389 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 7.0;retina: 1.9;testis: 3.2;thyroid gland: 5.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 208.7;Inhibitory neurons: 213.9;Oligodendrocyte precursor cells: 152.8;Oligodendrocytes: 197.6" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.9" "Region enriched" "Detected in some" 4 "cerebellum: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.7;GAMG: 6.7;hTERT-HME1: 4.7;SCLC-21H: 6.5;U-138 MG: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036963 Supported Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA036963: AB_10670378" "unprognostic (1.38e-4)" "unprognostic (8.62e-3)" "unprognostic (1.93e-1)" "unprognostic (3.90e-4)" "unprognostic (1.97e-1)" "unprognostic (4.43e-5)" "unprognostic (1.92e-1)" "unprognostic (1.88e-2)" "unprognostic (6.85e-2)" "unprognostic (1.56e-2)" "unprognostic (3.81e-1)" "unprognostic (4.85e-3)" "unprognostic (2.30e-4)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-3)" 0.0 0.7 0.4 0.0 0.6 0.0 0.0 7.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.2 0.0 0.6 0.0 0.4 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 0.2 0.0 5.0 0.0 0.0 0.0 0.0 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 9.7 2.2 1.2 0.0 0.0 0.0 0.0 0.1 6.7 3.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 4.7 1.1 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.0 0.0 0.0 1.9 6.5 2.0 0.0 0.0 3.6 0.8 0.0 0.0 1.6 6.4 3.2 0.0 0.9 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 7.0 1.0 0.4 0.3 0.4 0.2 0.4 0.1 0.2 1.6 0.0 0.0 0.0 30.3 0.0 0.0 0.1 0.0 0.0 30.1 0.2 0.0 2.2 0.0 0.0 0.0 27.1 0.0 0.0 0.0 3.9 0.3 17.0 11.6 2.9 0.2 0.0 0.0 208.7 0.6 0.0 0.2 0.0 29.3 0.0 0.9 0.0 0.0 0.0 52.2 213.9 0.0 0.0 0.0 0.0 5.0 0.6 0.2 0.0 3.7 0.0 1.6 0.0 152.8 197.6 0.3 0.0 0.0 0.0 0.7 0.0 0.4 0.0 29.4 0.0 0.9 0.2 6.0 16.8 0.0 0.0 0.0 0.1 0.7 0.0 0.2 TAGLN "DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10" ENSG00000149591 Transgelin Q01995 11 117199370-117207464 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 9628.1;intestine: 11712.2" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 2508.6;Peritubular cells: 2306.4;Sertoli cells: 2866.2;Smooth muscle cells: 4563.9" "Cancer enhanced" "Detected in all" "prostate cancer: 279.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 41.6;non-classical monocyte: 63.1" "Lineage enriched" "Detected in many" 12 "monocytes: 63.1" "Cell line enhanced" "Detected in all" "BJ: 1913.4;BJ hTERT+ SV40 Large T+: 1641.8;CACO-2: 1531.4;EFO-21: 2145.6;fHDF/TERT166: 2094.4;hTERT-RPE1: 1499.7;LHCN-M2: 1377.1;U-138 MG: 1598.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001447, HPA019467" Enhanced Approved Microtubules,Mitochondria,Cytosol No No 6300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Microtubules, Mitochondria" Cytosol "CAB001447: AB_564012, HPA019467: AB_1857245" "unprognostic (1.36e-2)" "unprognostic (1.06e-1)" "unprognostic (3.57e-3)" "unprognostic (1.91e-1)" "unprognostic (6.58e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (4.43e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.12e-7)" "unprognostic (9.58e-3)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" "unprognostic (2.52e-3)" 2235.7 512.7 118.5 963.9 144.4 12.1 1680.5 126.1 215.9 3611.3 172.5 11712.2 451.2 9628.1 693.9 1954.6 4610.6 893.8 1583.5 119.6 120.4 774.5 302.8 1258.6 245.5 137.0 127.0 1643.4 218.6 65.3 254.6 348.0 129.2 4624.1 1154.6 22.9 461.8 6383.6 356.4 619.8 1948.4 7108.7 127.2 532.0 3148.4 202.5 138.2 52.2 723.2 152.4 59.9 5521.7 2331.2 130.0 17.5 5.5 293.3 8.2 140.0 123.8 226.7 1913.4 788.1 1641.8 609.0 1531.4 28.4 3.2 2145.6 2094.4 1.7 46.1 4.4 16.8 543.3 6.8 4.4 5.0 66.9 130.2 708.7 1.7 5.2 304.6 57.5 267.1 36.1 1499.7 3.3 4.5 3.3 6.7 1377.1 4.5 1.7 15.8 84.6 18.8 2.1 2.7 23.1 12.0 4.4 25.8 1.9 9.6 29.9 11.0 1.5 807.6 9.2 5.1 182.0 1598.8 276.9 14.4 86.6 8.9 8.8 21.7 9.1 7.7 6.2 1.8 2.7 0.1 0.3 41.6 0.5 3.6 0.1 0.0 3.2 5.1 0.2 0.1 0.3 0.0 63.1 1.6 0.5 2.1 118.5 144.4 126.1 215.9 119.6 120.4 137.0 127.0 129.2 127.2 138.2 130.0 264.8 38.5 6.1 4.6 10.3 63.9 453.4 248.6 10.8 9.9 74.0 2508.6 1.3 4.3 22.5 40.5 18.8 57.0 8.6 3.1 0.0 577.8 3.3 14.6 455.5 260.3 3.0 2.7 4.5 74.5 35.3 464.4 41.3 12.8 1.3 32.4 639.7 8.9 41.5 1.7 6.5 18.3 24.4 23.1 91.8 23.9 48.4 33.8 96.0 37.5 8.1 4.9 2.1 3.0 11.9 38.4 4.5 2306.4 3.2 414.0 12.1 2.2 23.0 9.9 2866.2 177.6 4563.9 6.0 13.7 8.6 60.9 32.2 15.1 8.3 3.1 62.0 TAGLN2 "HA1756, KIAA0120" ENSG00000158710 "Transgelin 2" P37802 1 159918107-159925507 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2404.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA001925 Approved Approved "Actin filaments,Cytosol" "Intracellular and membrane" NA NA 270000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Actin filaments" "HPA001925: AB_1857756" "prognostic unfavorable (2.06e-5)" "unprognostic (2.56e-1)" "unprognostic (4.05e-2)" "unprognostic (1.27e-1)" "unprognostic (3.69e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (7.07e-5)" "unprognostic (4.61e-2)" "unprognostic (1.50e-1)" "unprognostic (3.21e-1)" "unprognostic (3.56e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.92e-10)" "unprognostic (1.81e-1)" "unprognostic (9.22e-2)" "unprognostic (3.95e-2)" "unprognostic (2.50e-2)" 401.9 154.7 103.7 356.0 103.2 437.3 355.4 106.3 115.0 266.6 94.9 337.4 314.3 220.5 94.9 494.0 231.9 282.6 351.1 101.1 152.7 307.9 254.4 687.7 321.1 141.7 117.6 170.9 284.7 81.0 100.0 378.2 122.9 208.5 307.9 46.1 388.7 205.2 83.4 418.2 356.3 254.4 125.2 479.7 698.8 127.0 125.9 309.6 210.2 139.6 386.4 436.1 350.0 114.9 1382.3 723.7 22.3 8.3 266.8 646.6 835.4 760.0 872.6 1635.2 799.8 786.6 1049.3 862.0 628.0 954.9 495.0 1054.3 378.1 1039.9 978.8 974.3 355.5 1140.7 651.8 50.0 322.7 808.2 1221.4 667.4 776.9 1030.4 504.3 1134.7 1029.0 260.3 494.8 578.9 586.1 563.0 378.1 601.2 619.3 947.6 1457.7 2.9 391.7 1275.3 376.6 527.7 340.7 325.6 900.7 1435.1 410.3 1190.6 756.5 814.2 1147.3 955.1 1134.4 876.9 2078.0 230.8 110.6 525.0 1238.3 541.3 603.8 1458.4 742.0 3160.6 558.9 449.7 499.9 866.5 620.0 544.6 1177.7 680.2 321.6 360.3 3746.8 817.6 356.9 1966.4 756.1 2257.9 103.7 103.2 106.3 115.0 101.1 152.7 141.7 117.6 122.9 125.2 125.9 114.9 617.1 179.5 130.5 0.3 507.8 549.1 330.6 454.3 307.9 31.6 257.0 201.8 12.8 121.5 221.4 183.9 18.8 497.4 567.6 371.0 74.3 1273.4 54.3 289.4 145.9 509.6 317.8 197.6 0.1 1206.9 2404.5 405.2 545.3 242.7 418.8 32.0 265.2 64.1 443.7 3.3 0.6 445.5 284.8 285.9 952.4 85.9 118.7 651.5 334.4 16.9 911.4 66.3 186.4 0.5 1.6 877.4 263.2 63.9 393.4 337.5 324.2 208.2 275.9 25.6 184.1 358.3 324.3 14.3 20.7 494.1 572.5 230.4 393.6 136.7 271.7 405.9 TBC1D15 "DKFZp761D0223, FLJ12085" ENSG00000121749 "TBC1 domain family member 15" Q8TC07 12 71839707-71927248 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013388, HPA015592" Supported Supported Mitochondria,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Mitochondria, Cytosol" "HPA013388: AB_2199233, HPA015592: AB_1857789" "unprognostic (3.87e-2)" "prognostic favorable (7.06e-4)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (4.63e-2)" "unprognostic (6.13e-3)" "unprognostic (2.96e-2)" "unprognostic (3.10e-1)" "unprognostic (2.61e-1)" "unprognostic (1.02e-2)" "unprognostic (4.07e-2)" "unprognostic (2.18e-1)" "prognostic favorable (5.34e-4)" "unprognostic (5.73e-2)" "unprognostic (4.34e-2)" "unprognostic (2.31e-1)" "unprognostic (2.78e-1)" 28.4 25.9 9.9 15.7 13.2 42.2 25.4 11.8 17.0 21.0 8.4 15.5 15.5 21.3 13.0 16.3 15.1 21.6 15.3 9.4 11.1 22.6 30.6 21.4 22.5 13.2 12.4 22.3 23.8 23.0 14.3 23.4 13.2 17.8 14.9 14.1 22.6 13.0 43.4 18.1 17.8 18.3 11.3 21.8 17.2 18.5 10.5 24.9 27.9 25.5 19.8 17.8 14.9 18.5 21.0 20.3 17.1 18.4 35.2 38.8 25.6 20.8 58.5 30.6 39.7 13.9 18.4 26.9 14.0 21.6 21.9 13.7 22.3 15.7 32.6 23.1 18.0 23.5 17.0 12.3 29.9 33.1 17.1 35.0 20.5 23.1 39.3 39.7 26.9 25.7 27.9 16.0 25.4 15.3 24.9 25.3 37.4 19.2 17.4 17.9 19.1 29.3 23.3 18.6 18.9 17.3 29.5 25.9 26.2 23.7 26.5 23.1 25.3 23.9 10.6 26.5 14.4 38.1 36.1 35.5 14.3 22.6 21.8 2.6 5.7 7.8 6.1 5.5 6.8 4.3 7.5 5.8 5.1 4.2 9.5 8.6 11.7 5.7 8.1 2.8 10.8 5.4 9.9 13.2 11.8 17.0 9.4 11.1 13.2 12.4 13.2 11.3 10.5 18.5 83.4 48.1 69.3 42.4 34.7 58.6 33.6 23.8 25.6 33.7 30.2 25.5 24.8 24.3 38.5 18.4 10.4 20.4 43.1 18.3 13.7 29.3 160.8 38.1 40.4 53.3 13.8 27.8 60.3 25.5 15.5 44.5 17.3 82.0 34.1 30.8 79.2 35.6 24.0 52.2 57.7 22.0 20.3 54.2 41.8 26.7 34.8 46.0 32.0 35.6 27.5 29.9 16.5 45.2 85.7 25.1 11.0 32.7 33.9 39.9 21.5 39.8 49.8 25.6 19.7 58.2 35.7 76.9 24.5 18.1 68.5 38.3 39.2 38.8 15.0 37.1 TBC1D23 FLJ11046 ENSG00000036054 "TBC1 domain family member 23" Q9NUY8 3 100260992-100325251 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038151, HPA038152" Approved Enhanced "Golgi apparatus" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA038151: AB_10672405, HPA038152: AB_10672620" "unprognostic (9.23e-3)" "unprognostic (6.01e-2)" "unprognostic (2.77e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (1.79e-2)" "unprognostic (6.18e-2)" "unprognostic (7.87e-3)" "unprognostic (6.16e-2)" "unprognostic (7.92e-2)" "unprognostic (2.02e-2)" "unprognostic (2.98e-3)" "unprognostic (3.66e-3)" "unprognostic (1.14e-1)" "unprognostic (1.83e-1)" "unprognostic (1.51e-1)" "unprognostic (5.64e-2)" "unprognostic (2.32e-1)" 15.1 17.4 4.8 12.7 7.0 23.0 14.8 10.8 6.7 13.5 5.0 15.1 17.9 14.3 10.2 16.2 9.3 13.9 14.3 5.9 6.4 17.1 22.7 12.6 12.5 6.6 5.4 16.2 18.2 17.9 5.1 21.6 7.1 11.7 15.5 16.8 15.2 9.9 17.2 13.5 18.4 14.1 7.0 12.5 15.2 17.1 6.7 14.4 14.1 15.3 15.5 15.6 8.2 10.9 72.9 15.0 17.4 9.8 34.4 44.3 17.5 40.4 45.7 46.6 53.6 28.6 13.3 18.3 20.6 46.9 26.0 25.5 64.5 29.4 72.4 9.0 15.1 49.9 16.6 19.3 33.9 23.2 39.1 35.9 23.7 23.3 38.1 39.0 25.2 14.1 41.0 26.8 30.1 16.3 17.9 11.4 20.3 26.2 27.8 14.8 37.9 21.6 27.3 16.3 24.8 13.5 23.4 18.4 29.8 22.7 19.6 22.0 24.1 32.9 30.9 15.5 26.9 25.6 28.1 31.8 42.1 21.2 27.4 27.8 17.8 22.7 12.2 20.5 12.4 12.0 11.7 10.7 18.7 12.7 10.3 10.9 10.2 21.8 24.8 8.2 17.4 17.4 4.8 7.0 10.8 6.7 5.9 6.4 6.6 5.4 7.1 7.0 6.7 10.9 24.0 41.7 12.6 19.6 24.5 31.5 18.6 14.8 16.5 18.6 17.9 11.7 26.1 11.5 20.5 12.9 14.6 20.1 19.1 24.8 31.3 26.8 46.8 17.5 28.4 22.5 7.2 54.1 50.9 29.5 19.3 31.9 13.7 31.7 29.8 19.0 13.9 19.0 13.9 35.3 42.4 17.5 18.3 17.1 20.2 44.2 20.5 21.9 24.9 48.7 14.0 18.7 12.3 41.7 56.4 36.1 16.9 14.3 34.5 22.3 21.1 19.9 19.3 30.2 13.1 27.6 25.9 20.8 15.2 20.4 38.8 65.8 21.1 21.8 14.3 30.2 TBX3 "TBX3-ISO, UMS, XHL" ENSG00000135111 "T-box transcription factor 3" O15119 12 114670255-114684175 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 178.4" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 613.9" "Cancer enhanced" "Detected in all" "prostate cancer: 49.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 103.0;BJ hTERT+: 97.3;RT4: 129.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005799, HPA075876" Supported Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA005799: AB_1857817, HPA075876: " "unprognostic (3.27e-1)" "unprognostic (2.64e-1)" "unprognostic (2.84e-1)" "unprognostic (1.11e-1)" "unprognostic (3.40e-2)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (2.99e-2)" "unprognostic (9.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (3.06e-1)" "unprognostic (3.64e-3)" "unprognostic (1.09e-3)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "prognostic favorable (3.28e-4)" 13.3 178.4 5.1 2.5 4.7 0.0 34.1 3.9 5.7 37.5 2.9 7.4 37.6 32.8 44.6 2.8 24.0 4.5 13.2 3.8 14.9 12.9 31.3 32.8 1.4 4.6 4.4 44.2 2.9 1.0 12.9 41.3 4.8 80.4 3.7 1.8 18.9 53.2 10.4 14.9 30.3 10.0 3.8 7.0 6.0 1.3 6.6 1.3 50.0 16.5 1.7 53.9 34.2 3.7 2.4 18.2 0.0 0.0 26.1 35.6 40.1 103.0 97.3 39.0 38.3 16.3 4.4 0.0 1.6 18.0 2.4 4.7 8.4 3.6 47.7 0.0 12.3 0.0 4.8 48.1 8.4 0.0 0.0 16.0 2.4 13.1 26.8 0.0 0.5 0.0 3.8 0.0 3.4 1.6 0.0 0.5 0.2 53.0 5.4 0.0 0.0 2.6 0.0 129.3 6.6 19.4 14.6 6.6 3.6 44.6 5.1 0.2 0.0 11.9 7.7 6.8 33.9 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.7 3.9 5.7 3.8 14.9 4.6 4.4 4.8 3.8 6.6 3.7 48.9 0.0 1.9 0.3 1.8 9.8 85.2 5.8 7.4 14.3 110.3 80.5 12.5 0.0 1.1 35.0 4.2 60.7 0.7 12.0 0.0 0.6 1.5 3.3 144.7 38.6 4.9 0.0 0.0 0.0 7.0 41.3 5.1 3.8 0.0 3.9 1.1 40.2 6.1 1.7 0.0 23.9 4.1 0.9 4.6 2.8 5.3 2.9 3.6 14.0 0.0 1.9 0.0 0.0 0.0 0.3 22.4 6.0 0.0 72.4 37.9 0.1 0.4 2.0 39.5 27.2 58.2 0.1 3.8 3.2 9.8 613.9 2.0 112.0 12.1 69.1 TBX5 HOS ENSG00000089225 "T-box transcription factor 5" Q99593 12 114353911-114408442 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 88.1;lung: 20.8;placenta: 28.7" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 104.7" "Cancer enhanced" "Detected in some" "lung cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 18.9;BJ hTERT+: 41.5;BJ hTERT+ SV40 Large T+: 9.2;BJ hTERT+ SV40 Large T+ RasG12V: 12.2;HAP1: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008786, HPA064683" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA008786: AB_10601720, HPA064683: AB_2685320" "unprognostic (3.09e-2)" "unprognostic (1.53e-1)" "unprognostic (3.79e-2)" "unprognostic (2.75e-1)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-7)" "unprognostic (2.29e-2)" "unprognostic (1.68e-2)" "unprognostic (7.34e-2)" "unprognostic (4.38e-3)" 3.4 0.0 0.1 0.0 0.0 0.0 4.4 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 88.1 0.9 0.0 0.0 0.0 20.8 0.6 0.3 0.1 0.0 0.0 1.3 0.0 28.7 0.3 3.4 0.0 0.3 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 5.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 18.9 41.5 9.2 12.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 16.3 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.9 0.0 0.3 0.1 0.3 0.0 0.0 0.2 2.9 0.0 0.6 1.6 0.0 0.1 0.0 0.0 0.0 4.5 0.1 0.1 104.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.1 0.0 0.0 0.0 2.1 0.3 0.0 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 7.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 TCTA ENSG00000145022 "T cell leukemia translocation altered" P57738 3 49412206-49416475 "Disease related genes, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007342 Approved Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "HPA007342: AB_2202399" "unprognostic (5.58e-2)" "unprognostic (4.33e-2)" "unprognostic (6.86e-2)" "unprognostic (5.71e-3)" "unprognostic (2.17e-2)" "unprognostic (3.35e-2)" "unprognostic (2.18e-1)" "prognostic favorable (6.76e-4)" "unprognostic (3.74e-1)" "unprognostic (3.38e-3)" "unprognostic (1.82e-3)" "unprognostic (1.03e-1)" "prognostic favorable (5.00e-15)" "unprognostic (1.68e-1)" "unprognostic (1.96e-1)" "unprognostic (3.43e-1)" "unprognostic (6.41e-3)" 21.7 48.0 49.1 13.1 52.3 12.3 21.5 50.1 52.9 23.2 47.0 24.7 18.9 23.1 60.6 15.6 26.1 16.6 22.6 48.4 50.6 51.0 41.9 23.5 15.8 51.6 51.6 27.1 24.1 39.8 48.8 14.5 52.3 34.5 28.8 14.0 21.8 25.1 19.6 14.2 23.1 21.8 48.8 25.9 23.3 15.7 52.1 20.1 45.3 13.8 16.0 25.4 15.9 51.5 12.8 15.5 9.8 14.8 42.5 18.5 12.9 26.0 19.2 25.8 21.6 9.1 13.6 15.2 18.6 61.5 29.6 14.4 19.3 26.2 21.0 22.9 13.4 25.4 19.6 11.9 25.8 10.9 31.9 40.2 26.8 28.7 22.9 24.7 27.0 12.0 9.4 33.8 63.8 11.7 13.4 9.8 8.0 24.1 35.5 8.1 10.6 36.0 44.5 16.7 26.3 8.7 30.9 33.8 28.6 19.7 28.8 10.2 24.5 19.3 11.9 40.4 9.8 18.4 26.1 10.4 45.4 19.3 27.2 20.4 17.8 23.2 19.1 34.2 11.1 12.0 12.0 14.7 10.1 13.7 14.9 15.5 20.1 23.0 47.5 15.6 17.8 22.4 49.1 52.3 50.1 52.9 48.4 50.6 51.6 51.6 52.3 48.8 52.1 51.5 15.5 25.6 15.6 8.8 19.3 2.7 10.0 10.3 14.2 10.2 19.9 18.0 14.1 20.0 12.9 27.6 12.5 25.9 20.5 34.0 46.9 15.3 8.0 15.5 15.0 14.7 17.5 9.0 12.3 11.6 11.5 17.6 53.5 17.0 5.7 7.1 11.4 31.8 24.8 10.1 11.0 19.1 20.3 18.6 6.0 14.3 15.5 19.2 14.2 11.2 15.5 26.3 26.8 11.1 16.8 15.1 28.6 16.1 13.2 13.4 34.9 50.3 22.8 11.3 6.6 13.7 16.6 8.2 6.1 10.4 4.5 20.0 21.6 22.1 16.6 7.9 TEAD1 "AA, TCF13, TEF-1" ENSG00000187079 "TEA domain transcription factor 1" P28347 11 12674421-12944737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 230.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057339, HPA062471" Enhanced Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA057339: AB_2683413, HPA062471: AB_2684773" "unprognostic (1.00e-1)" "unprognostic (2.53e-2)" "unprognostic (8.84e-2)" "unprognostic (9.93e-3)" "unprognostic (2.05e-2)" "unprognostic (4.50e-1)" "unprognostic (1.50e-1)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" "unprognostic (4.40e-3)" "unprognostic (8.39e-2)" "unprognostic (4.76e-2)" "unprognostic (1.41e-2)" "unprognostic (7.08e-3)" "unprognostic (2.52e-1)" "unprognostic (3.14e-1)" "unprognostic (2.18e-2)" 29.5 12.1 11.1 8.2 11.6 0.0 17.8 8.6 8.5 23.4 30.6 36.1 7.7 26.4 7.1 29.8 19.2 18.5 31.3 14.5 14.8 17.2 13.6 15.9 4.2 15.1 12.3 21.9 15.2 27.1 14.4 33.3 10.5 18.8 13.0 10.5 10.2 20.1 67.5 13.2 11.9 27.2 13.3 7.3 16.4 8.6 15.6 4.2 17.8 72.6 5.6 33.9 14.7 12.9 62.8 52.1 43.9 58.7 59.9 62.1 65.4 89.2 76.2 71.6 69.7 53.8 54.5 0.4 23.0 120.9 32.3 37.0 53.7 35.9 115.5 0.2 17.6 0.0 107.3 18.1 55.8 0.0 4.7 51.8 18.3 50.4 68.2 58.6 15.2 3.9 26.0 0.2 111.2 13.1 0.1 0.6 17.2 14.5 23.5 0.3 64.8 33.2 48.2 37.2 26.9 31.2 90.9 43.1 59.0 63.8 20.0 4.4 32.0 107.8 76.2 84.9 59.5 8.6 17.3 12.0 41.6 0.2 69.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 11.6 8.6 8.5 14.5 14.8 15.1 12.3 10.5 13.3 15.6 12.9 37.9 89.8 21.7 230.8 0.4 99.3 32.2 19.3 39.9 12.9 16.4 20.2 75.0 31.5 33.1 49.7 12.5 24.1 0.2 11.0 1.9 16.6 6.5 80.8 97.4 33.3 46.7 0.0 101.8 12.8 52.4 46.5 18.8 142.9 0.0 57.7 25.7 39.8 3.7 1.7 108.4 13.5 10.2 1.9 16.0 7.2 23.6 1.9 24.9 91.8 0.0 31.2 0.0 121.2 69.7 34.8 8.1 24.0 1.4 69.4 6.7 29.8 53.8 17.5 6.6 73.5 46.7 3.0 22.3 29.9 54.8 12.3 2.0 45.5 10.4 54.6 TENM2 "KIAA1127, ODZ2, Ten-M2, TEN2" ENSG00000145934 "Teneurin transmembrane protein 2" Q9NT68 5 167284799-168264157 "Predicted membrane proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 9.8;heart muscle: 35.1" "Group enriched" "Detected in many" 5 "Astrocytes: 512.9;Excitatory neurons: 706.2;Inhibitory neurons: 965.9" "Cancer enriched" "Detected in many" 6 "head and neck cancer: 15.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 66.1;HBEC3-KT: 43.0;HDLM-2: 43.3;U-138 MG: 74.6;U-2 OS: 64.0;U-251 MG: 50.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038018, HPA038420, HPA068691" Uncertain Approved Nucleoli No No 11000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli "HPA038018: , HPA038420: AB_10674682, HPA068691: AB_2686019" "unprognostic (6.00e-2)" "unprognostic (1.50e-1)" "unprognostic (2.94e-2)" "unprognostic (9.16e-3)" "unprognostic (3.88e-3)" "unprognostic (3.81e-3)" "unprognostic (5.81e-2)" "unprognostic (2.41e-1)" "unprognostic (4.62e-2)" "unprognostic (2.10e-2)" "unprognostic (3.68e-3)" "unprognostic (4.34e-2)" "unprognostic (4.69e-5)" "unprognostic (3.47e-2)" "unprognostic (1.03e-1)" "unprognostic (5.16e-4)" "prognostic unfavorable (7.52e-4)" 0.1 0.5 2.9 0.0 4.7 0.0 1.9 0.0 9.8 1.3 0.0 0.2 0.4 0.0 0.5 1.9 0.1 0.4 35.1 6.0 1.2 0.8 1.3 0.2 0.0 0.6 0.1 0.7 0.1 0.0 0.7 0.0 1.6 2.2 0.1 4.1 0.5 1.0 0.0 3.2 0.2 0.0 0.0 0.0 0.1 1.3 4.3 2.2 0.4 0.5 1.0 0.1 2.0 0.0 0.1 0.0 13.4 0.0 0.0 0.4 0.0 1.9 0.0 0.7 1.8 0.0 0.0 0.0 0.0 66.1 1.7 0.0 0.0 43.0 0.8 43.3 0.0 0.0 0.2 0.0 2.0 0.0 0.0 3.0 7.4 0.3 5.3 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.3 9.8 0.2 0.0 0.0 6.6 0.0 0.1 0.0 0.1 2.4 3.8 0.1 0.0 74.6 64.0 0.1 50.0 0.0 0.0 0.0 7.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 4.7 0.0 9.8 6.0 1.2 0.6 0.1 1.6 0.0 4.3 0.0 0.5 0.0 0.0 512.9 0.0 14.8 1.1 20.3 33.6 15.5 0.3 13.0 144.0 0.0 1.4 0.0 18.8 0.0 0.0 1.0 0.0 3.4 23.5 0.1 0.3 1.7 0.0 0.0 706.2 0.2 0.0 2.2 0.0 0.2 1.3 1.6 0.4 5.1 0.1 121.1 965.9 0.7 0.0 0.0 1.2 18.2 4.4 0.2 1.8 36.5 0.0 2.3 0.0 21.6 12.8 0.0 0.0 61.7 0.0 1.4 0.3 0.0 0.6 1.8 0.0 0.4 1.5 1.2 1.1 1.4 1.7 0.0 0.1 0.0 0.4 0.1 TGFB1 "CED, DPD1, TGFB, TGFbeta" ENSG00000105329 "Transforming growth factor beta 1" 19 41301587-41353922 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 438.3;Extravillous trophoblasts: 452.1;Macrophages: 188.8;NK-cells: 223.5;T-cells: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000361, HPA073356" Approved Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 1290000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" Cytosol "CAB000361: AB_2201910, HPA073356: " "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (3.29e-2)" "unprognostic (4.90e-2)" "unprognostic (3.75e-3)" "prognostic unfavorable (3.38e-4)" "unprognostic (8.51e-3)" "unprognostic (5.63e-3)" "unprognostic (2.47e-2)" "unprognostic (5.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.88e-1)" "prognostic unfavorable (1.19e-8)" "unprognostic (1.65e-3)" "unprognostic (2.79e-2)" "unprognostic (6.39e-2)" "unprognostic (4.86e-3)" 39.8 28.6 10.8 39.7 10.7 82.9 25.4 11.8 9.4 53.2 9.5 31.0 14.4 45.9 7.4 52.2 27.7 18.1 35.8 9.5 15.5 35.8 14.7 63.4 34.0 24.5 14.9 17.4 14.3 11.5 18.0 32.1 17.6 31.6 8.4 0.6 21.2 19.8 8.1 29.3 37.8 21.8 18.4 88.9 20.1 8.1 19.4 16.7 20.2 8.3 25.7 44.1 45.3 17.7 57.7 87.6 3.4 0.3 41.7 35.3 10.0 81.9 64.4 25.2 15.4 40.4 30.1 57.0 88.6 110.5 26.8 30.1 17.8 54.6 11.1 76.6 17.9 199.0 18.0 50.4 47.7 54.9 119.6 45.0 17.5 50.5 32.7 138.7 135.2 21.1 108.0 116.8 27.9 42.1 43.1 79.6 9.4 12.0 52.7 44.4 13.1 85.4 46.8 20.3 0.3 6.5 23.9 0.1 15.1 32.5 1.9 36.3 170.3 96.4 77.2 20.7 91.2 74.4 31.7 36.3 90.3 106.4 16.4 1.1 0.8 3.9 0.7 1.2 0.6 0.2 0.3 0.4 0.5 0.3 0.2 0.3 2.4 0.3 0.8 0.9 0.3 0.9 10.8 10.7 11.8 9.4 9.5 15.5 24.5 14.9 17.6 18.4 19.4 17.7 55.0 0.0 0.0 3.3 120.6 44.4 36.5 64.8 38.7 0.2 14.4 9.7 2.3 4.3 17.2 16.5 0.0 5.4 438.3 1.4 0.0 12.8 1.0 5.7 18.2 63.1 0.0 28.0 1.6 17.1 452.1 34.3 14.3 5.0 64.9 20.0 71.4 2.7 141.2 0.0 2.1 1.4 22.4 136.1 158.6 1.8 12.2 188.8 23.2 30.0 105.8 0.3 223.5 0.0 0.6 45.1 16.4 18.0 156.5 32.9 0.4 9.0 9.7 0.7 39.5 13.9 78.6 3.1 8.0 40.3 18.9 55.7 221.9 4.1 0.8 31.1 TGFB1I1 "ARA55, Hic-5, TSC-5" ENSG00000140682 "Transforming growth factor beta 1 induced transcript 1" O43294 16 31471585-31477960 "Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 265.6;intestine: 264.4" "Cell type enhanced" "Detected in many" "Leydig cells: 92.2;Peritubular cells: 179.0;Sertoli cells: 223.5;Smooth muscle cells: 176.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 9.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 100.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB020844 Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 800000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" Cytosol "CAB020844: " "unprognostic (5.80e-2)" "unprognostic (3.09e-2)" "unprognostic (5.34e-2)" "unprognostic (1.18e-1)" "unprognostic (6.64e-2)" "unprognostic (9.52e-2)" "unprognostic (1.89e-1)" "unprognostic (4.95e-2)" "unprognostic (4.19e-2)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.06e-8)" "unprognostic (1.06e-2)" "unprognostic (6.57e-2)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.73e-5)" 65.5 17.0 4.8 22.7 5.1 1.0 52.8 4.6 6.9 119.0 4.4 264.4 14.5 265.6 12.4 38.2 143.2 14.4 48.5 4.6 4.7 26.6 9.7 54.7 4.8 5.6 4.6 78.6 8.2 8.6 8.2 19.7 5.0 87.6 23.9 0.7 21.0 80.8 13.1 28.5 61.7 106.1 4.7 33.0 78.5 10.2 5.1 1.4 26.8 10.5 4.9 171.1 73.6 4.4 13.3 16.6 25.9 0.0 25.4 46.1 0.3 70.8 64.8 43.6 30.1 6.6 4.5 0.0 65.1 62.3 29.1 20.6 6.0 13.3 56.4 0.1 0.3 17.5 29.1 3.7 67.4 0.0 19.8 31.1 18.7 27.5 16.3 100.0 29.2 0.0 1.5 0.0 51.9 0.1 0.0 1.6 1.4 1.4 16.2 0.0 30.9 0.1 12.5 6.6 0.0 19.0 27.5 0.2 14.1 20.9 0.1 1.7 82.4 79.8 19.2 21.4 31.8 0.1 0.1 0.2 34.9 0.8 49.6 9.5 0.0 0.1 0.2 0.0 0.3 0.9 0.9 0.1 0.0 0.2 0.1 0.6 0.2 0.0 0.0 0.3 1.6 1.3 4.8 5.1 4.6 6.9 4.6 4.7 5.6 4.6 5.0 4.7 5.1 4.4 76.9 6.4 4.8 0.0 0.4 12.6 23.9 34.8 14.8 0.4 4.1 71.5 13.4 5.7 3.4 7.3 0.0 1.2 1.5 1.8 7.9 33.3 1.2 3.6 76.2 48.8 0.0 11.0 0.1 22.5 1.2 64.4 4.6 2.9 6.3 35.3 29.6 0.3 14.6 0.0 0.1 4.7 0.0 0.3 15.4 3.3 92.2 9.3 40.9 2.8 4.2 7.0 0.0 3.5 0.1 28.4 2.2 179.0 1.4 20.1 13.3 19.7 1.1 1.4 223.5 17.4 176.0 1.5 3.6 1.9 11.2 1.8 2.6 20.3 5.3 4.6 THOC5 "C22orf19, Fmip, fSAP79, KIAA0983, PK1.3" ENSG00000100296 "THO complex 5" Q13769 22 29505879-29555216 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 125.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048402 Supported Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA048402: AB_2680387" "unprognostic (1.16e-1)" "unprognostic (3.05e-1)" "unprognostic (7.77e-2)" "unprognostic (2.27e-2)" "unprognostic (7.20e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (3.76e-6)" "unprognostic (6.34e-2)" "unprognostic (5.54e-2)" "unprognostic (2.55e-1)" "unprognostic (2.45e-1)" "unprognostic (8.81e-2)" "prognostic unfavorable (3.65e-4)" "unprognostic (9.53e-2)" "unprognostic (1.24e-1)" "unprognostic (1.24e-1)" "unprognostic (2.97e-1)" 19.3 11.6 5.4 14.2 7.2 19.0 17.2 9.2 10.1 24.4 3.5 37.5 11.4 31.9 13.6 18.5 20.3 17.2 29.2 6.4 7.3 13.4 13.5 14.7 15.3 8.6 7.1 21.5 14.5 14.1 9.3 11.2 9.6 18.2 13.8 11.1 11.9 20.9 43.7 13.8 17.5 29.3 5.0 15.0 20.3 19.8 7.2 14.7 11.3 40.9 15.1 28.7 17.6 9.6 43.0 28.7 25.8 77.5 47.7 38.1 32.7 79.3 46.7 68.8 68.0 46.8 18.8 26.4 30.2 63.4 40.9 37.8 36.5 42.4 67.0 30.5 38.5 43.6 40.8 53.0 32.5 100.1 35.8 40.6 39.2 67.8 52.1 56.0 51.2 25.9 50.2 26.3 43.3 47.7 31.2 31.1 53.6 36.7 22.1 45.3 62.1 32.7 25.2 32.4 52.6 84.5 44.1 34.8 49.3 33.9 19.7 35.0 35.5 120.6 69.8 28.7 52.0 41.2 42.7 64.9 40.2 40.9 52.5 6.7 15.6 39.4 14.1 19.5 14.1 12.6 11.6 10.3 17.2 10.1 12.1 11.3 42.8 10.6 24.4 4.1 18.3 13.0 5.4 7.2 9.2 10.1 6.4 7.3 8.6 7.1 9.6 5.0 7.2 9.6 8.5 22.4 12.6 7.2 11.1 5.4 7.8 9.5 4.0 10.8 10.7 16.3 17.0 4.3 8.9 3.7 20.9 21.3 9.5 8.2 13.7 20.0 43.6 7.0 11.0 10.1 9.0 16.6 9.5 14.7 22.6 12.1 9.7 6.5 11.4 15.9 7.9 8.6 14.2 8.4 11.0 5.6 6.1 11.7 5.7 125.7 12.8 9.6 8.8 2.8 16.9 7.3 18.6 6.6 6.6 17.4 6.4 12.8 10.4 8.9 18.7 17.9 9.2 25.1 0.0 10.9 19.5 39.2 23.5 9.4 6.1 17.4 11.1 17.9 9.4 5.6 THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 286.8;smooth muscle: 304.7;urinary bladder: 216.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.6;Excitatory neurons: 116.0;Fibroblasts: 201.9;Inhibitory neurons: 104.1;Muller glia cells: 108.1;Proximal tubular cells: 199.9;Smooth muscle cells: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 461.3;BJ: 738.4;BJ hTERT+: 832.5;fHDF/TERT166: 1330.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB068243: AB_2665687, CAB068244: AB_2665688, HPA003733: AB_1846340" "unprognostic (9.98e-2)" "unprognostic (2.71e-1)" "unprognostic (5.13e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.43e-2)" "unprognostic (1.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-3)" "unprognostic (3.38e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (2.40e-6)" "unprognostic (1.75e-2)" "unprognostic (1.90e-2)" "unprognostic (3.03e-2)" "unprognostic (1.14e-2)" 90.6 16.4 97.9 78.6 114.8 0.2 25.6 12.9 286.8 78.9 0.0 35.4 10.2 58.6 27.8 29.4 23.1 101.0 12.9 135.4 73.3 142.2 7.4 21.6 40.4 83.6 37.0 9.2 14.8 39.4 18.1 62.0 60.8 15.5 41.8 25.3 8.5 47.0 3.4 13.9 14.5 304.7 35.4 21.9 17.4 11.4 43.6 73.2 37.9 8.3 35.6 216.7 21.7 108.7 0.7 3.9 108.5 0.1 461.3 331.5 0.3 738.4 832.5 263.6 289.3 0.2 0.2 0.4 0.1 1330.6 121.9 0.9 4.3 1.1 200.7 65.1 0.0 41.5 14.4 0.0 142.7 0.0 0.2 247.5 0.0 335.6 11.6 355.2 0.3 22.6 0.0 0.6 206.5 0.1 0.6 0.1 173.9 0.0 1.4 0.5 50.7 0.3 0.1 0.2 18.1 47.9 0.1 0.4 0.2 32.9 1.0 2.1 0.0 368.6 120.9 107.3 110.1 0.3 19.7 0.4 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.9 114.8 12.9 286.8 135.4 73.3 83.6 37.0 60.8 35.4 43.6 108.7 68.2 0.0 1.8 17.3 2.1 17.7 0.3 1.7 0.0 27.2 1.6 40.0 0.9 0.0 0.0 9.2 0.0 1.9 0.2 0.0 21.5 0.9 1.0 5.1 141.6 69.2 0.0 0.0 116.0 0.0 2.6 201.9 1.5 3.2 1.3 0.0 17.5 0.1 4.0 32.0 104.1 0.0 0.0 0.0 25.0 2.7 96.3 2.7 17.8 21.5 0.0 108.1 0.0 64.3 22.7 0.4 0.0 77.5 0.1 0.3 0.0 199.9 0.0 27.5 32.9 9.3 226.6 0.3 0.6 0.2 17.6 4.0 4.5 6.2 0.0 0.6 TIMP3 SFD ENSG00000100234 "TIMP metallopeptidase inhibitor 3" P35625 22 32801705-32863041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1663.5;Fibroblasts: 967.5;Leydig cells: 1398.6;Peritubular cells: 1934.1;Sertoli cells: 2327.1;Smooth muscle cells: 1116.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 502.6;BJ: 1173.0;BJ hTERT+: 514.7;fHDF/TERT166: 1073.7;WM-115: 893.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068391 Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "HPA068391: " "unprognostic (4.98e-2)" "unprognostic (1.77e-3)" "unprognostic (1.60e-1)" "unprognostic (8.53e-4)" "unprognostic (1.67e-2)" "unprognostic (1.05e-2)" "unprognostic (7.01e-2)" "unprognostic (3.22e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (1.90e-5)" "unprognostic (3.92e-1)" "unprognostic (1.95e-1)" "prognostic favorable (1.50e-4)" "unprognostic (2.66e-3)" "unprognostic (1.44e-2)" "unprognostic (2.55e-3)" "unprognostic (3.11e-2)" 805.5 288.7 71.7 41.4 74.9 1.1 556.9 68.7 72.6 376.1 221.0 190.4 30.5 393.3 230.4 168.1 373.9 153.5 532.8 64.3 79.2 248.0 92.0 625.1 69.5 83.2 86.7 116.2 81.1 139.5 139.1 999.5 76.0 178.8 81.2 31.7 178.7 341.1 128.1 170.3 122.1 379.6 70.3 187.2 152.1 64.1 106.2 41.1 340.1 325.9 28.8 197.4 261.1 59.5 19.6 0.0 16.9 2.7 502.6 280.6 1.0 1173.0 514.7 94.1 110.8 20.5 0.3 0.1 28.1 1073.7 3.6 18.3 3.2 48.4 135.0 0.1 14.3 147.4 23.5 52.4 197.4 0.1 59.7 47.4 120.4 166.9 9.5 3.4 0.0 0.0 0.1 0.9 44.6 1.2 0.4 5.0 2.5 0.0 0.8 0.1 3.4 0.4 2.1 97.0 12.5 16.8 24.1 0.5 322.9 266.6 0.7 1.3 0.0 7.9 25.2 245.9 19.1 0.2 0.4 0.4 232.3 0.2 893.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.7 74.9 68.7 72.6 64.3 79.2 83.2 86.7 76.0 70.3 106.2 59.5 1663.5 365.4 35.9 101.9 5.3 77.4 766.2 49.5 10.2 4.0 31.2 177.2 279.9 14.3 22.2 51.5 4.2 492.2 4.6 0.3 3.9 2.5 14.9 27.9 747.6 677.3 1.8 35.3 26.1 0.7 433.7 967.5 21.4 23.9 89.2 11.4 743.9 102.0 109.2 3.3 15.7 0.0 24.4 39.3 95.0 57.7 1398.6 28.6 76.5 116.2 0.7 146.6 0.0 52.3 0.8 0.9 0.0 1934.1 9.5 159.5 0.0 15.5 8.5 5.5 2327.1 339.2 1116.6 6.2 7.0 14.3 56.4 809.0 21.5 4.8 0.7 163.4 TLE4 "E(spl), ESG, GRG4" ENSG00000106829 "TLE family member 4, transcriptional corepressor" Q04727 9 79571773-79726882 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 108.0" "Cell type enhanced" "Detected in all" "Early spermatids: 818.9;Late spermatids: 1315.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 99.9;BJ hTERT+: 98.7;BJ hTERT+ SV40 Large T+: 89.4;fHDF/TERT166: 154.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065357 Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA065357: AB_2685479" "unprognostic (6.68e-2)" "unprognostic (8.50e-3)" "unprognostic (2.13e-3)" "unprognostic (2.92e-1)" "unprognostic (1.91e-1)" "unprognostic (9.79e-2)" "unprognostic (1.24e-2)" "unprognostic (4.83e-1)" "unprognostic (2.83e-1)" "unprognostic (1.62e-1)" "unprognostic (9.94e-3)" "unprognostic (1.04e-1)" "prognostic favorable (6.94e-4)" "unprognostic (1.49e-1)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" 9.3 15.7 18.4 16.4 45.2 67.9 8.7 22.3 27.4 9.6 20.2 9.9 8.4 14.3 5.9 17.6 12.9 16.6 8.0 27.5 21.6 6.9 5.6 12.5 15.9 31.7 21.4 32.3 6.4 10.6 24.2 19.7 32.2 5.6 10.5 24.7 10.9 8.4 23.1 18.9 11.3 14.5 26.1 18.5 14.1 108.0 25.4 27.8 10.4 10.3 19.9 18.7 12.8 64.0 0.0 19.0 70.7 0.5 11.4 9.6 21.2 99.9 98.7 89.4 34.4 2.8 10.3 7.4 0.2 154.3 13.7 20.8 5.0 18.3 39.2 38.2 30.8 0.0 9.1 0.4 13.8 21.4 13.0 11.3 12.6 26.1 5.2 25.2 23.9 14.0 1.5 21.3 28.6 0.7 29.4 9.4 22.5 11.9 4.8 25.7 35.9 7.4 5.5 2.7 28.5 41.5 14.7 1.9 0.1 32.8 0.0 25.1 36.4 34.8 0.1 0.8 5.0 14.4 25.0 10.9 12.3 18.0 16.6 24.2 4.4 17.1 4.8 6.3 5.9 1.3 2.5 3.6 2.9 1.7 1.5 2.5 11.7 3.2 4.9 1.0 0.8 2.6 18.4 45.2 22.3 27.4 27.5 21.6 31.7 21.4 32.2 26.1 25.4 64.0 108.9 6.4 19.4 77.4 91.9 121.0 57.2 50.6 167.4 76.8 76.0 92.8 15.9 84.4 45.6 14.7 127.2 77.2 228.1 163.5 3.9 13.4 818.9 262.0 230.0 59.7 25.2 22.3 150.8 22.0 67.1 71.4 137.1 158.7 21.0 34.8 53.2 14.1 51.1 218.7 33.3 117.3 61.1 167.9 70.4 1315.5 105.6 101.7 42.7 77.8 75.3 31.0 88.6 301.6 381.0 31.7 207.6 46.6 152.7 37.8 122.0 18.1 50.4 290.2 72.3 280.7 83.9 38.3 146.0 140.0 90.8 65.0 141.0 86.8 96.0 99.9 TLN1 "ILWEQ, TLN" ENSG00000137076 "Talin 1" Q9Y490 9 35696948-35732195 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 323.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002006, HPA004748" Supported Supported "Plasma membrane,Focal adhesion sites,Centriolar satellite,Cytosol" NA NA 1300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites, Cytosol" "Plasma membrane, Centriolar satellite" "CAB002006: , HPA004748: AB_1857760" "unprognostic (9.71e-2)" "unprognostic (2.02e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (1.96e-1)" "unprognostic (5.55e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-2)" "unprognostic (5.07e-2)" "unprognostic (1.94e-1)" "unprognostic (6.46e-2)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "prognostic favorable (7.21e-4)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (7.83e-2)" "unprognostic (8.83e-3)" 125.7 62.7 31.1 84.7 42.1 79.2 79.4 39.3 31.1 80.0 43.1 196.2 36.5 151.8 25.3 78.0 102.9 53.2 81.2 26.2 34.9 47.3 42.3 91.8 63.1 50.8 41.9 66.0 33.1 41.6 36.7 70.4 49.7 72.6 41.4 7.7 42.5 111.4 70.9 46.7 77.9 145.4 41.5 89.7 91.8 23.3 44.9 61.1 49.0 55.8 52.7 147.7 66.3 44.6 63.4 103.8 62.7 86.9 210.8 158.7 71.4 171.2 186.8 162.9 146.4 86.3 27.4 76.5 55.5 319.0 103.0 33.3 74.2 106.9 118.3 172.8 48.0 173.0 132.1 77.4 130.6 105.8 276.2 193.4 50.2 240.1 112.7 223.7 253.4 64.7 60.2 76.0 218.5 27.8 71.5 27.8 51.3 28.4 78.8 95.0 36.6 44.8 81.4 49.8 14.1 59.6 83.7 46.3 53.4 56.5 39.3 72.6 308.5 257.8 99.6 80.0 140.6 26.2 27.6 51.7 199.9 55.9 238.4 6.0 5.9 7.3 5.4 6.1 4.4 2.6 3.1 4.1 4.3 2.3 1.4 3.1 10.0 4.1 8.1 5.4 2.3 6.9 31.1 42.1 39.3 31.1 26.2 34.9 50.8 41.9 49.7 41.5 44.9 44.6 123.2 109.0 66.9 11.4 99.8 40.1 69.4 43.5 42.7 11.7 40.3 61.3 134.1 31.5 55.7 53.3 10.4 44.3 186.3 43.8 23.5 94.3 47.2 36.0 156.9 106.8 34.1 127.0 7.7 61.9 82.6 103.9 51.0 73.0 206.6 72.0 93.9 54.7 112.4 15.2 7.6 29.0 26.4 196.9 91.0 26.4 99.4 323.4 23.2 21.5 174.1 33.0 288.4 4.5 9.1 107.7 33.2 128.6 61.4 58.4 40.6 62.8 34.3 17.6 203.8 126.5 267.9 32.0 28.5 47.4 26.6 58.8 143.8 89.4 28.9 46.4 TMED2 "P24A, p24b1, p24beta1, RNP24" ENSG00000086598 "Transmembrane p24 trafficking protein 2" Q15363 12 123584533-123598582 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014060 Approved Supported Vesicles NA NA 82000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA014060: AB_1856389" "unprognostic (6.36e-2)" "unprognostic (3.38e-3)" "unprognostic (5.41e-3)" "unprognostic (1.75e-2)" "unprognostic (2.98e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.57e-3)" "unprognostic (2.20e-2)" "unprognostic (4.31e-2)" "unprognostic (9.76e-3)" "unprognostic (1.03e-2)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.35e-7)" "unprognostic (2.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (9.87e-2)" 106.0 97.1 40.7 92.6 43.5 122.1 136.1 44.2 50.8 155.6 59.5 132.5 123.7 102.5 203.3 111.9 102.3 96.1 116.5 40.5 45.3 102.8 271.1 85.4 72.7 46.6 46.6 101.5 229.1 99.3 65.0 125.4 46.9 140.5 140.7 56.9 227.6 102.2 131.0 74.8 110.5 102.1 46.0 63.2 133.8 58.5 44.2 69.1 197.6 112.1 95.2 118.6 71.4 53.8 237.7 204.9 133.4 232.2 295.7 260.2 317.5 401.2 318.5 246.8 194.2 209.9 198.9 199.3 210.7 398.7 169.4 228.1 181.8 214.5 257.3 155.2 169.3 217.3 114.0 267.6 559.5 296.9 178.1 220.5 349.2 212.6 286.0 352.7 234.7 133.5 223.1 132.9 255.6 175.1 159.8 242.7 192.9 201.0 206.6 164.8 216.8 235.7 303.9 349.1 166.5 143.1 267.3 263.6 273.7 160.0 450.2 237.2 226.2 210.1 132.4 204.9 227.5 292.3 290.7 167.6 248.3 192.9 254.2 249.7 143.2 145.9 157.0 147.5 198.8 111.8 137.0 148.4 158.6 102.5 110.3 129.4 111.1 148.5 141.3 242.5 140.1 142.2 40.7 43.5 44.2 50.8 40.5 45.3 46.6 46.6 46.9 46.0 44.2 53.8 97.1 48.1 71.5 9.1 148.8 417.4 290.3 348.5 207.1 50.1 258.8 98.0 167.2 213.1 233.2 154.5 20.9 281.5 166.9 169.6 117.4 325.1 12.2 89.2 136.5 142.0 170.7 76.3 20.0 249.6 678.6 242.7 156.5 136.8 92.6 88.4 143.5 538.8 215.8 48.8 20.3 352.4 321.4 141.7 414.3 13.9 181.4 128.5 378.8 17.8 129.8 124.1 195.7 19.6 27.5 224.9 158.5 153.4 521.0 486.3 178.1 163.0 142.1 54.7 164.3 112.6 193.5 165.9 150.6 289.8 498.8 451.9 154.3 125.0 263.9 389.2 TMED7-TICAM2 ENSG00000251201 "TMED7-TICAM2 readthrough" 5 115578642-115626161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Astrocytes: 2.9;Excitatory neurons: 4.8;Inhibitory neurons: 5.1;Microglial cells: 4.7;Oligodendrocyte precursor cells: 5.5;Oligodendrocytes: 13.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA008960 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008960: AB_1080280" "unprognostic (7.37e-6)" "unprognostic (5.18e-4)" "unprognostic (2.84e-2)" "unprognostic (8.53e-2)" "unprognostic (5.16e-2)" "unprognostic (5.79e-3)" "unprognostic (1.47e-3)" "unprognostic (6.56e-5)" "unprognostic (1.03e-1)" "unprognostic (8.25e-2)" "unprognostic (3.91e-3)" "unprognostic (1.20e-1)" "unprognostic (8.61e-5)" "unprognostic (1.25e-1)" "unprognostic (5.19e-2)" "unprognostic (2.32e-2)" "unprognostic (6.42e-2)" 1.9 2.6 1.2 2.9 1.3 1.0 1.6 1.5 2.6 3.2 0.7 1.9 1.8 1.7 1.8 1.2 1.6 1.7 0.8 1.0 1.3 2.1 2.5 2.0 1.8 1.7 1.5 1.3 1.5 1.7 0.4 4.1 1.7 2.0 1.9 2.8 1.3 3.0 0.4 0.4 2.0 2.6 1.6 2.6 2.3 0.9 1.5 1.9 2.0 1.0 2.7 2.6 0.4 2.0 4.1 2.9 2.7 10.9 16.2 30.7 10.2 19.0 14.9 11.2 19.9 2.5 9.6 1.1 8.4 21.4 7.7 8.1 1.8 11.4 22.1 9.4 2.1 0.7 1.5 0.3 12.1 2.2 5.5 15.1 9.9 12.5 12.8 19.6 7.0 1.6 1.4 3.3 13.7 4.6 1.7 0.5 0.4 9.6 4.4 1.4 4.6 1.3 9.2 2.2 2.1 3.1 8.8 0.9 15.6 11.1 1.5 3.1 11.8 10.4 11.3 9.8 16.8 5.7 4.5 1.2 11.1 3.1 8.2 1.8 3.4 1.3 0.5 3.9 1.1 0.4 0.4 0.6 3.4 0.3 0.4 0.4 1.1 0.6 3.1 0.5 0.8 1.3 1.2 1.3 1.5 2.6 1.0 1.3 1.7 1.5 1.7 1.6 1.5 2.0 0.0 3.2 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 4.8 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 5.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 4.7 1.1 0.0 0.0 5.5 13.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.2 TMEM117 DKFZp434K2435 ENSG00000139173 "Transmembrane protein 117" Q9H0C3 12 43835967-44389762 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 65.6;Excitatory neurons: 220.2;Inhibitory neurons: 190.3;Microglial cells: 80.6;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 152.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046223 Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046223: AB_10960636" "unprognostic (1.37e-2)" "unprognostic (2.99e-1)" "unprognostic (4.32e-1)" "unprognostic (2.39e-2)" "unprognostic (3.57e-2)" "unprognostic (7.08e-2)" "unprognostic (3.07e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (3.94e-4)" "unprognostic (2.89e-1)" "unprognostic (6.26e-2)" "unprognostic (1.99e-3)" "unprognostic (1.74e-2)" "unprognostic (2.30e-2)" "unprognostic (2.65e-1)" "unprognostic (9.20e-3)" "unprognostic (3.80e-1)" 1.8 1.9 0.9 1.2 1.4 0.1 2.7 1.5 2.1 3.8 8.8 3.4 6.0 4.0 2.6 5.8 2.3 3.5 4.2 1.3 1.3 2.2 2.1 1.1 1.4 2.4 1.5 2.5 3.7 4.1 1.7 3.0 2.8 3.5 3.5 2.3 2.1 5.2 3.3 4.0 4.2 4.0 1.4 0.7 2.1 2.4 1.3 0.9 2.3 3.3 2.3 4.1 3.8 2.6 1.2 0.4 4.0 6.7 4.5 9.6 0.1 12.6 6.2 2.3 2.7 10.0 4.3 4.5 0.9 9.0 0.6 6.4 2.6 2.8 1.7 1.9 7.4 1.2 2.5 4.0 1.3 1.8 4.7 5.0 9.9 1.3 0.7 9.2 0.4 0.5 2.2 1.9 4.4 1.1 0.0 1.1 0.8 0.0 2.4 3.0 4.5 1.8 4.5 2.7 0.6 6.1 4.8 1.5 10.2 1.6 0.3 4.7 1.5 3.4 1.1 1.8 3.3 3.4 3.9 2.6 1.7 2.0 1.2 0.0 0.0 0.0 1.2 0.0 1.7 1.0 0.3 1.2 0.0 0.9 0.5 0.6 0.0 0.4 0.0 0.1 0.2 0.4 0.9 1.4 1.5 2.1 1.3 1.3 2.4 1.5 2.8 1.4 1.3 2.6 3.2 0.0 1.3 65.6 8.4 6.5 4.8 3.4 9.6 3.9 2.4 2.8 5.4 2.8 2.5 7.3 4.2 15.0 2.8 6.9 3.9 2.8 25.8 3.9 5.5 2.1 0.0 1.7 220.2 3.0 2.7 3.8 18.3 6.0 2.5 6.0 4.2 2.7 5.6 5.0 190.3 4.2 12.2 3.8 2.5 9.5 6.2 2.1 12.4 80.6 0.1 3.4 3.1 123.1 152.4 2.5 19.2 6.4 11.2 2.1 13.8 1.3 2.7 5.2 0.0 2.2 3.8 1.4 5.5 17.7 12.1 11.5 5.1 2.3 5.0 4.9 TMEM200A "KIAA1913, TTMC" ENSG00000164484 "Transmembrane protein 200A" Q86VY9 6 130366017-130443067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.5;Distal enterocytes: 23.3;Endometrial stromal cells: 18.6;Enteroendocrine cells: 24.6;Granulosa cells: 49.9" "Cancer enhanced" "Detected in many" "renal cancer: 7.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.0" "Cell line enhanced" "Detected in many" "HBF TERT88: 40.8;hTEC/SVTERT24-B: 67.1;hTERT-RPE1: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014396 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA014396: AB_2204904" "unprognostic (1.07e-1)" "unprognostic (4.89e-2)" "unprognostic (2.33e-1)" "unprognostic (4.19e-2)" "unprognostic (7.62e-2)" "unprognostic (2.35e-1)" "unprognostic (3.28e-2)" "unprognostic (2.91e-1)" "unprognostic (7.25e-2)" "unprognostic (9.29e-2)" "unprognostic (3.10e-1)" "unprognostic (2.27e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.27e-3)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (1.91e-3)" 5.7 17.1 1.7 3.9 2.5 0.1 5.9 0.1 2.2 11.1 0.0 11.1 7.3 39.3 5.3 1.2 12.9 6.4 0.6 4.5 2.7 13.6 0.4 6.8 3.8 0.9 4.6 15.6 1.5 0.8 5.3 3.3 1.5 2.7 22.3 11.2 1.6 1.4 0.6 2.0 8.3 18.7 0.8 1.0 6.3 2.7 3.8 4.7 5.6 0.4 3.4 5.6 3.5 0.8 0.1 0.1 0.2 0.0 11.7 14.6 0.1 10.6 13.0 11.1 19.6 16.6 0.0 0.0 0.0 22.3 2.5 2.5 1.0 0.0 40.8 15.5 0.0 0.0 0.0 0.8 5.3 0.3 0.0 16.7 0.0 67.1 13.3 33.5 0.4 0.3 0.0 1.5 5.2 0.0 0.0 0.1 8.4 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 13.4 12.5 4.0 1.1 1.9 8.2 0.0 0.0 7.4 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.5 0.2 0.8 0.4 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.1 1.7 2.5 0.1 2.2 4.5 2.7 0.9 4.6 1.5 0.8 3.8 0.8 0.5 0.0 0.5 1.3 0.2 2.0 0.1 0.1 1.2 26.5 0.5 0.4 0.6 0.0 0.0 0.0 0.0 0.5 0.4 23.3 0.0 0.0 2.0 5.2 18.6 0.8 24.6 2.7 7.1 0.0 1.7 3.6 2.0 0.7 0.0 49.9 0.0 0.0 0.2 13.5 4.3 1.6 0.0 0.0 0.9 1.8 5.9 0.3 1.8 1.9 0.0 0.5 0.0 1.0 0.3 0.1 6.0 10.5 3.3 0.0 4.6 9.9 0.0 2.1 0.0 0.8 8.4 3.3 2.6 0.1 1.4 0.5 5.8 11.3 4.0 0.1 TMEM200B TTMB ENSG00000253304 "Transmembrane protein 200B" Q69YZ2 1 29119429-29123903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 60.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 8.8;Fibroblasts: 6.1;Leydig cells: 12.8;Melanocytes: 8.8;Peritubular cells: 15.1;Sertoli cells: 6.6;Smooth muscle cells: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 28.2;BJ hTERT+ SV40 Large T+: 26.7;BJ hTERT+ SV40 Large T+ RasG12V: 29.5;fHDF/TERT166: 29.0;HBF TERT88: 25.3" "Low region specificity" "Detected in all" HPA055254 Uncertain NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA055254: AB_2682760" "unprognostic (2.55e-1)" "unprognostic (2.12e-2)" "unprognostic (8.25e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-3)" "unprognostic (6.84e-2)" "unprognostic (1.91e-1)" "unprognostic (1.52e-2)" "unprognostic (6.25e-2)" "unprognostic (1.33e-1)" "unprognostic (6.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.24e-2)" "unprognostic (1.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-3)" 16.8 4.4 2.0 4.0 6.3 0.0 11.8 6.9 3.3 47.2 6.6 29.5 2.3 60.6 7.8 5.6 21.5 7.3 7.0 1.9 2.4 9.4 8.4 10.5 1.2 2.2 2.1 33.3 2.5 26.1 3.6 6.5 2.2 24.6 4.1 0.3 4.1 39.7 2.2 5.8 9.2 35.1 2.0 6.4 6.4 13.3 2.6 1.0 5.0 2.6 1.3 20.9 24.3 2.1 21.0 0.0 3.4 0.0 28.2 23.4 1.1 14.4 22.6 26.7 29.5 1.1 2.3 0.0 3.5 29.0 9.8 0.4 2.3 0.0 25.3 0.1 0.9 0.1 5.7 1.8 19.6 0.0 0.1 12.5 2.7 20.1 3.9 1.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.3 1.9 0.0 5.8 0.0 0.0 0.0 0.3 0.1 0.0 1.7 20.7 0.0 0.1 9.5 0.0 0.0 0.0 9.4 0.4 19.9 0.4 0.0 0.0 0.0 11.6 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 6.3 6.9 3.3 1.9 2.4 2.2 2.1 2.2 2.0 2.6 2.1 2.0 3.2 0.6 0.7 0.2 1.9 0.4 0.2 2.8 0.8 0.6 1.8 1.0 1.5 0.7 0.0 2.1 0.1 0.2 0.1 0.0 0.0 0.1 1.0 8.8 1.3 0.0 0.0 0.3 0.0 0.5 6.1 0.0 0.6 0.0 0.0 1.1 1.2 0.1 0.0 0.1 0.0 0.0 0.0 1.2 2.4 12.8 0.1 8.8 1.9 0.1 0.1 0.0 0.0 0.1 0.0 0.1 15.1 0.0 0.3 0.0 5.9 0.4 1.9 6.6 1.1 9.5 0.3 0.6 0.2 0.6 0.5 0.4 0.0 0.0 0.3 TMEM214 FLJ20254 ENSG00000119777 "Transmembrane protein 214" Q6NUQ4 2 27032910-27041694 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034551 Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Golgi apparatus, Cytosol" "HPA034551: AB_10602481" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.10e-1)" "unprognostic (4.12e-3)" "unprognostic (1.90e-2)" "unprognostic (2.42e-2)" "prognostic unfavorable (4.96e-4)" "unprognostic (1.96e-1)" "unprognostic (3.70e-1)" "unprognostic (2.40e-1)" "unprognostic (1.96e-1)" "unprognostic (2.74e-2)" "prognostic unfavorable (2.39e-10)" "unprognostic (1.54e-2)" "unprognostic (1.97e-2)" "unprognostic (2.04e-1)" "unprognostic (2.92e-2)" 45.8 39.0 14.7 30.8 15.8 23.1 43.2 15.3 17.3 45.0 28.7 38.3 30.5 43.7 66.2 31.5 37.5 30.7 36.7 14.8 17.0 30.0 46.5 37.7 25.1 19.1 18.7 41.4 79.9 56.0 60.4 45.8 18.3 37.9 41.7 8.8 83.6 44.4 35.7 37.8 33.6 45.1 15.6 37.4 40.8 19.5 17.8 21.7 42.3 21.3 34.4 36.7 33.9 14.9 82.4 53.5 32.2 68.2 102.8 103.7 69.4 105.9 142.4 76.0 85.2 53.0 67.3 37.6 52.4 156.6 59.7 57.6 39.3 74.9 61.0 36.3 44.1 49.9 41.4 109.8 128.1 45.7 82.5 90.4 52.7 66.8 112.0 58.6 83.5 24.3 46.0 75.3 85.9 59.6 23.3 34.1 23.1 110.0 42.8 31.3 58.5 91.0 57.1 57.0 27.8 32.3 49.4 83.3 38.2 31.0 45.9 27.0 72.4 55.2 52.8 57.0 60.4 100.9 73.3 59.2 71.1 56.8 77.9 5.7 3.5 2.8 3.9 3.8 5.0 2.5 3.0 2.8 2.8 2.8 1.5 2.1 0.6 5.6 2.2 5.0 2.6 2.5 14.7 15.8 15.3 17.3 14.8 17.0 19.1 18.7 18.3 15.6 17.8 14.9 15.8 3.2 20.1 3.9 18.5 7.6 9.6 10.4 3.4 9.3 19.8 11.0 8.2 21.5 15.0 14.7 10.4 43.6 15.0 37.5 1.9 24.7 6.4 11.3 25.4 17.5 17.9 18.5 4.8 34.6 62.9 26.9 33.1 23.8 14.5 17.0 32.5 28.9 27.3 6.7 4.4 37.6 10.2 18.9 12.8 7.8 32.6 11.7 5.4 6.5 14.6 6.9 14.4 4.0 3.8 21.7 22.3 20.3 63.0 20.8 25.4 10.4 11.0 8.4 26.3 11.6 19.6 24.4 12.7 8.4 9.2 71.7 12.0 17.6 27.6 15.8 TMEM26 "Em:AC068892.1, MGC35010" ENSG00000196932 "Transmembrane protein 26" Q6ZUK4 10 61406642-61453381 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.2;Endometrial stromal cells: 5.4;Excitatory neurons: 5.3;Hepatic stellate cells: 4.6;Inhibitory neurons: 4.8;Kupffer cells: 12.2;Late spermatids: 5.6;Theca cells: 15.0" "Group enriched" "Detected in some" 4 "breast cancer: 2.5;endometrial cancer: 1.0;prostate cancer: 1.8;renal cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.7;fHDF/TERT166: 1.1;HSkMC: 2.0;HUVEC TERT2: 1.5;MOLT-4: 2.3" "Region enhanced" "Detected in some" "hypothalamus: 2.3" "Low region specificity" "Detected in all" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.21e-3)" "unprognostic (2.84e-1)" "unprognostic (7.34e-2)" "unprognostic (7.83e-2)" "unprognostic (1.38e-3)" "unprognostic (1.30e-1)" "unprognostic (7.56e-2)" "unprognostic (3.69e-2)" "unprognostic (3.13e-1)" "unprognostic (9.41e-2)" "unprognostic (5.38e-2)" "unprognostic (5.24e-2)" "unprognostic (2.29e-5)" "unprognostic (2.55e-2)" "unprognostic (1.51e-2)" "unprognostic (8.53e-2)" "unprognostic (1.95e-1)" 0.5 0.5 1.3 0.9 1.4 0.1 5.2 0.3 1.1 2.3 0.2 0.7 1.4 4.0 0.1 0.5 0.4 1.0 0.2 1.1 0.8 2.2 2.5 1.4 0.7 0.8 1.0 0.5 0.0 1.4 0.2 1.5 0.4 2.6 0.9 0.0 0.0 2.4 0.8 0.0 0.8 2.0 0.5 8.8 0.2 3.6 1.5 2.1 0.4 0.2 0.2 0.7 0.5 0.7 0.0 0.0 0.1 0.0 0.1 0.8 0.1 0.0 4.7 0.4 0.6 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.0 0.0 0.5 0.0 0.5 1.5 0.5 0.0 0.0 0.1 0.0 2.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.4 0.3 1.1 1.1 0.8 0.8 1.0 0.4 0.5 1.5 0.7 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 2.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 0.7 5.4 1.7 0.0 0.0 5.3 0.0 0.0 1.4 0.0 1.6 0.0 0.1 4.6 0.2 0.3 0.0 4.8 0.0 0.0 12.2 0.0 5.6 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.2 0.0 1.7 0.0 0.0 0.0 0.1 1.2 0.5 0.2 0.0 0.1 0.0 0.1 15.0 0.0 0.0 TMEM263 "C12orf23, MGC17943" ENSG00000151135 "Transmembrane protein 263" Q8WUH6 12 106955719-106978778 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014453, HPA042339" Uncertain Approved Vesicles NA NA 14000 "Cluster 40: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA014453: , HPA042339: AB_10795503" "unprognostic (2.56e-2)" "unprognostic (1.41e-1)" "unprognostic (8.99e-2)" "unprognostic (5.65e-2)" "unprognostic (3.90e-1)" "unprognostic (3.46e-2)" "prognostic unfavorable (7.84e-4)" "unprognostic (4.66e-2)" "unprognostic (6.01e-2)" "unprognostic (3.11e-2)" "unprognostic (7.07e-2)" "unprognostic (1.19e-1)" "unprognostic (3.05e-3)" "unprognostic (3.49e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.53e-1)" 20.6 27.1 14.5 20.4 15.6 7.4 22.3 14.2 18.2 41.6 21.8 17.8 17.3 28.3 33.4 9.5 16.2 30.4 28.6 15.5 22.1 29.4 44.6 15.3 21.1 13.2 17.1 29.3 23.4 20.7 37.5 43.2 16.5 28.5 19.2 16.8 21.0 21.6 11.5 8.6 15.3 29.9 13.3 16.4 30.9 19.4 21.4 31.0 33.6 14.2 19.7 22.1 13.9 13.5 32.7 28.2 54.1 37.4 125.8 141.6 23.5 123.1 114.0 59.0 74.6 30.1 14.0 3.2 37.5 174.3 33.3 14.9 34.4 48.6 80.9 61.5 38.0 45.5 41.0 65.0 65.1 2.4 28.3 98.6 23.1 63.9 53.8 137.3 73.4 35.1 22.1 12.1 83.6 26.7 35.4 21.4 17.7 21.1 60.3 77.1 41.3 7.9 60.7 27.3 28.2 38.6 67.3 31.2 51.2 41.9 36.5 13.7 86.7 50.6 30.7 66.9 31.6 50.8 31.5 30.3 39.2 7.7 79.4 11.7 1.4 1.6 15.8 1.6 18.3 15.7 15.2 13.7 4.3 16.8 26.8 24.9 1.0 19.8 0.6 14.8 17.4 13.9 14.5 15.6 14.2 18.2 15.5 22.1 13.2 17.1 16.5 13.3 21.4 13.5 31.6 9.6 23.6 12.1 33.5 0.0 52.0 0.0 53.5 24.4 47.7 25.8 55.4 22.8 11.2 23.9 31.3 40.4 54.3 12.4 92.0 19.2 34.8 19.9 75.7 26.4 28.8 10.9 15.4 33.0 72.6 61.5 50.0 32.4 29.9 33.7 33.2 44.4 13.5 11.8 16.5 65.1 0.0 6.7 0.0 37.2 47.2 10.4 0.0 22.5 9.6 34.1 22.6 24.1 8.4 17.3 13.2 43.6 68.3 48.6 23.0 47.7 12.4 21.0 26.3 39.1 41.7 51.2 22.5 12.7 0.0 36.0 36.3 30.6 16.4 44.2 TMEM39A "FLJ10902, SUSR2" ENSG00000176142 "Transmembrane protein 39A" Q9NV64 3 119428949-119468830 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039140 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Vesicles "HPA039140: AB_10673303" "unprognostic (2.16e-1)" "unprognostic (8.75e-2)" "unprognostic (4.25e-2)" "unprognostic (6.86e-2)" "unprognostic (1.56e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (9.68e-2)" "unprognostic (6.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.00e-5)" "unprognostic (4.07e-1)" "unprognostic (2.52e-2)" "unprognostic (1.88e-1)" "unprognostic (6.41e-2)" 12.4 10.5 2.2 14.4 4.3 12.9 10.2 4.1 3.5 19.5 10.9 9.0 10.0 13.2 10.9 9.0 11.7 12.6 11.1 2.2 3.1 6.4 13.0 12.4 10.0 4.0 3.4 13.1 28.4 12.8 15.4 18.1 4.3 9.1 9.3 5.0 13.3 14.3 7.2 8.8 8.0 9.7 3.1 9.2 9.8 7.8 4.7 12.1 16.6 11.9 13.6 14.4 10.5 6.2 28.3 15.1 24.1 17.4 56.1 54.2 24.1 26.4 54.3 37.2 50.0 26.1 21.2 12.0 27.4 28.7 37.9 28.7 29.3 12.1 38.0 12.6 11.2 15.5 13.5 25.4 37.9 27.1 23.4 29.7 20.5 25.9 61.5 37.5 23.6 18.5 16.1 35.5 19.6 14.1 13.7 7.0 20.5 29.8 31.5 16.5 11.3 25.7 9.2 10.7 10.7 15.8 26.6 15.2 33.4 17.3 14.8 23.8 18.5 20.2 17.2 13.8 17.3 39.5 12.5 28.5 27.6 18.2 26.8 12.7 10.9 7.3 11.7 5.8 11.9 7.7 7.1 9.6 12.3 9.0 5.6 6.1 3.8 11.9 4.6 17.3 8.9 9.4 2.2 4.3 4.1 3.5 2.2 3.1 4.0 3.4 4.3 3.1 4.7 6.2 8.5 9.6 15.8 9.8 14.3 22.8 16.0 21.8 8.6 4.7 14.6 10.8 10.8 7.2 16.2 7.3 6.2 26.5 24.7 7.4 5.9 11.6 22.8 8.2 26.3 10.8 10.8 9.0 12.4 14.2 57.6 28.9 13.3 17.9 1.3 13.5 7.9 12.0 13.3 1.7 14.0 18.3 6.1 15.0 54.9 6.8 17.1 17.8 10.6 12.2 31.0 3.9 9.2 25.1 21.8 10.2 6.6 13.2 57.8 20.6 8.0 3.0 14.9 6.4 6.6 15.9 25.2 26.1 18.5 9.6 21.7 59.8 17.4 9.4 11.1 20.4 TMEM47 "BCMP1, DKFZp564E153, DKFZP761J17121, TM4SF10, VAB-9" ENSG00000147027 "Transmembrane protein 47" Q9BQJ4 X 34627075-34657285 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 110.7;Astrocytes: 85.5;Leydig cells: 74.3;Muller glia cells: 148.0;Peritubular cells: 92.9;Sertoli cells: 92.1;Skeletal myocytes: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 112.6;fHDF/TERT166: 348.1;RPTEC TERT1: 83.6;U-2197: 74.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046658 Approved Approved "Nuclear membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear membrane" "HPA046658: AB_2679742" "unprognostic (1.50e-1)" "unprognostic (1.44e-1)" "unprognostic (5.97e-2)" "unprognostic (1.35e-1)" "unprognostic (1.52e-1)" "unprognostic (3.82e-2)" "unprognostic (6.74e-3)" "unprognostic (7.29e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.67e-2)" "unprognostic (4.23e-2)" "unprognostic (1.36e-1)" "prognostic favorable (4.05e-6)" "unprognostic (2.69e-2)" "unprognostic (7.19e-2)" "unprognostic (2.76e-1)" "unprognostic (9.94e-2)" 40.0 20.8 34.8 8.5 38.3 0.0 18.8 27.1 39.5 46.7 41.6 25.9 8.6 45.7 33.4 34.6 35.1 28.6 36.1 30.8 35.8 27.7 24.8 21.9 6.2 36.5 38.7 21.7 11.3 5.6 6.6 1.2 33.7 32.9 14.9 17.8 29.6 45.6 23.8 6.3 11.5 51.0 37.8 7.5 13.8 4.9 39.5 3.1 20.2 31.1 4.2 36.2 20.1 33.4 0.0 1.7 50.7 21.4 43.8 33.1 0.0 112.6 0.3 21.8 18.7 0.1 0.0 0.0 9.2 348.1 0.0 0.1 14.5 4.0 32.0 0.0 9.9 0.0 13.2 0.0 25.3 0.0 0.0 30.0 0.1 8.9 9.7 38.9 24.8 0.0 0.0 0.0 41.6 0.9 0.0 0.0 6.0 0.6 0.3 0.0 25.3 0.0 83.6 33.0 0.5 0.0 0.1 1.3 0.0 5.4 0.2 0.0 0.9 44.0 4.4 74.4 4.8 0.0 0.0 0.0 18.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 38.3 27.1 39.5 30.8 35.8 36.5 38.7 33.7 37.8 39.5 33.4 110.7 19.2 0.6 85.5 0.1 8.2 15.9 0.9 1.8 8.3 10.8 12.7 27.7 10.0 1.5 16.5 6.2 0.0 0.6 0.0 7.9 0.8 0.4 7.6 4.6 29.8 0.0 0.0 4.3 5.3 0.2 48.3 1.1 6.2 2.5 0.7 46.4 17.5 0.1 30.3 25.6 0.0 0.0 0.8 11.7 3.8 74.3 1.2 65.8 13.1 0.0 148.0 0.0 5.0 2.2 3.0 0.0 92.9 0.1 14.3 0.0 13.4 2.0 7.3 92.1 84.7 67.1 0.3 2.1 1.9 5.3 0.1 0.7 0.8 0.0 12.1 TMEM50A SMP1 ENSG00000183726 "Transmembrane protein 50A" O95807 1 25338317-25362361 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065192 Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Actin filaments, Cytosol" "HPA065192: AB_2685429" "unprognostic (2.41e-2)" "unprognostic (2.74e-1)" "unprognostic (5.17e-3)" "prognostic favorable (8.64e-5)" "unprognostic (1.45e-1)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.34e-4)" "unprognostic (7.39e-2)" "unprognostic (7.92e-3)" "unprognostic (2.53e-1)" "unprognostic (1.02e-2)" "unprognostic (2.44e-2)" "unprognostic (2.39e-3)" "unprognostic (6.66e-2)" "unprognostic (2.91e-1)" "unprognostic (3.91e-3)" "unprognostic (3.44e-2)" 47.2 63.0 43.9 44.5 47.8 41.8 55.5 45.3 55.8 47.0 43.7 58.5 49.6 35.7 53.0 36.5 38.4 45.7 44.2 45.0 44.4 55.0 33.4 58.1 52.2 46.5 44.4 26.2 32.6 49.5 14.6 57.7 46.4 54.4 65.7 45.4 81.5 52.7 16.9 41.1 55.4 46.0 47.2 46.9 49.5 16.1 45.5 47.1 47.0 26.5 47.3 55.1 29.8 50.4 43.3 44.6 74.3 42.3 132.9 119.8 28.1 89.0 123.6 143.4 159.5 36.5 110.9 50.2 47.9 274.6 55.7 62.6 56.3 61.9 161.2 126.1 81.4 104.7 47.5 55.2 96.5 82.4 80.3 128.0 91.4 106.1 60.5 69.7 107.0 50.8 73.1 79.5 140.9 30.6 53.2 90.2 90.6 73.7 37.1 45.7 85.3 88.9 148.8 30.9 64.5 42.3 89.0 64.2 72.2 69.3 32.7 52.0 171.0 86.5 36.6 144.9 36.8 52.3 61.5 45.0 117.1 117.2 50.3 275.5 76.9 109.8 87.9 94.7 91.9 49.6 77.2 91.1 55.9 40.9 55.1 76.6 159.2 80.5 117.3 51.9 95.4 106.3 43.9 47.8 45.3 55.8 45.0 44.4 46.5 44.4 46.4 47.2 45.5 50.4 244.8 144.2 84.2 21.2 107.9 253.4 184.5 392.3 146.8 43.9 162.0 164.8 105.6 102.9 212.7 169.2 27.1 108.9 191.0 175.6 50.9 300.3 25.4 136.4 119.3 203.3 83.0 93.6 31.6 215.6 312.5 198.1 91.3 180.8 126.6 58.2 152.0 68.3 227.1 25.2 27.3 170.7 309.3 162.4 245.1 12.7 151.9 223.8 199.3 16.9 253.8 102.0 154.5 28.1 48.8 315.3 164.8 98.9 168.2 340.6 120.0 113.1 205.1 41.7 210.4 71.6 200.6 94.7 47.0 166.8 317.7 181.6 180.9 116.9 106.9 274.3 TMEM87B FLJ14681 ENSG00000153214 "Transmembrane protein 87B" Q96K49 2 112055269-112119318 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 89.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035183 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus, Vesicles" "HPA035183: AB_10600829" "unprognostic (3.19e-1)" "prognostic unfavorable (3.78e-4)" "unprognostic (1.26e-2)" "unprognostic (1.79e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (4.28e-4)" "prognostic unfavorable (4.72e-4)" "unprognostic (4.20e-3)" "unprognostic (1.85e-1)" "unprognostic (6.07e-2)" "unprognostic (2.87e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.32e-1)" "unprognostic (5.35e-2)" "unprognostic (1.05e-1)" "unprognostic (3.25e-3)" 10.5 12.2 6.8 14.7 6.6 7.9 20.1 6.1 8.0 12.9 6.9 28.4 28.6 11.0 18.5 10.5 8.4 12.1 5.0 5.9 7.1 7.9 7.4 11.7 15.4 7.5 10.0 6.0 11.3 12.9 9.2 15.1 8.0 30.7 27.8 6.9 15.4 15.9 3.1 13.7 30.5 13.4 7.1 15.5 22.8 5.0 8.3 9.7 15.0 4.2 14.6 17.1 9.0 6.9 21.7 6.4 5.9 25.8 24.9 32.6 21.4 35.5 46.8 21.9 26.7 16.6 28.6 20.9 18.2 47.3 30.2 34.9 3.8 21.6 28.7 12.8 4.1 27.5 4.6 15.2 24.7 19.6 28.9 22.3 25.9 28.0 22.0 21.4 23.6 9.6 16.9 13.1 31.8 13.7 9.3 10.8 4.8 35.0 16.4 7.6 8.9 17.0 20.3 30.2 4.6 6.4 15.4 38.6 34.6 15.5 20.4 14.7 26.6 22.3 6.8 17.6 7.8 10.6 18.1 12.9 25.9 10.1 16.3 5.4 3.0 2.6 3.2 5.2 5.6 5.9 6.9 4.4 2.7 4.9 6.2 3.6 1.8 3.5 6.7 2.7 7.4 3.6 6.8 6.6 6.1 8.0 5.9 7.1 7.5 10.0 8.0 7.1 8.3 6.9 18.3 28.9 13.9 18.9 23.3 12.2 14.5 20.9 39.9 5.0 32.9 14.4 4.6 20.0 21.6 18.4 2.1 15.9 12.3 59.5 0.0 42.9 18.7 14.4 26.5 19.9 17.4 6.3 18.4 89.3 25.5 17.5 46.4 24.9 13.3 14.5 35.7 10.1 21.7 6.7 16.4 53.6 12.2 37.7 10.9 24.5 9.9 22.7 3.6 30.0 20.9 4.0 6.2 21.6 23.1 69.7 47.1 3.0 21.6 28.9 44.9 4.7 17.9 7.9 0.0 5.4 17.2 4.9 5.6 29.9 12.8 29.1 20.5 11.8 38.2 23.9 TMTC3 "FLJ90492, SMILE" ENSG00000139324 "Transmembrane O-mannosyltransferase targeting cadherins 3" Q6ZXV5 12 88142296-88199887 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transferase "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038550 Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038550: AB_10672715" "unprognostic (1.05e-1)" "unprognostic (6.16e-2)" "unprognostic (1.50e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (5.28e-2)" "unprognostic (3.62e-3)" "unprognostic (1.71e-2)" "unprognostic (1.46e-1)" "unprognostic (4.44e-1)" "unprognostic (8.07e-3)" "unprognostic (2.56e-2)" "unprognostic (2.28e-1)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" 5.9 4.4 3.6 3.8 3.8 1.7 6.7 5.8 4.7 5.6 2.1 4.5 5.4 6.4 5.2 9.1 3.9 5.7 3.8 3.9 4.6 8.1 9.0 5.2 2.9 3.4 3.9 5.3 3.2 6.2 2.8 10.2 4.1 7.4 4.7 7.9 3.8 6.3 1.7 12.5 4.4 9.2 3.2 3.9 3.8 4.1 3.6 4.0 6.3 4.3 4.5 6.8 4.7 4.1 13.2 14.0 12.6 11.9 28.8 25.4 22.5 28.1 26.6 15.8 16.9 20.3 9.2 4.1 5.0 25.8 9.6 28.9 13.5 22.4 26.5 2.4 10.2 4.0 9.5 9.3 15.0 4.3 2.5 21.7 12.0 30.5 12.0 16.2 24.9 3.4 8.9 1.4 17.8 7.9 3.0 5.5 9.7 5.0 7.3 2.6 27.4 4.1 13.7 21.3 10.7 10.6 22.8 16.1 7.3 13.3 25.9 4.3 26.4 21.8 12.0 19.4 13.7 4.5 6.3 4.7 6.8 5.0 16.5 7.4 1.3 2.3 1.8 1.1 2.2 2.3 2.0 1.4 0.9 1.8 2.4 2.0 1.3 1.2 1.6 0.9 1.7 0.7 3.6 3.8 5.8 4.7 3.9 4.6 3.4 3.9 4.1 3.2 3.6 4.1 15.9 12.8 8.2 19.6 6.9 34.2 24.4 29.1 24.5 12.5 11.4 8.1 11.1 5.7 20.0 7.3 27.1 29.6 3.5 6.7 3.9 14.5 26.8 23.7 22.2 16.9 3.6 9.5 51.6 10.8 18.2 23.8 8.6 21.9 9.5 12.4 15.7 19.2 8.2 13.5 46.8 5.9 75.3 5.9 6.0 18.2 20.2 3.7 8.8 20.6 2.8 8.3 2.1 28.1 42.4 12.4 4.9 19.5 4.6 18.0 7.3 13.9 34.9 23.4 19.7 17.1 22.3 12.0 8.7 32.6 40.5 17.8 5.2 14.1 7.1 14.4 TMX3 "FLJ20793, KIAA1830, PDIA13, TXNDC10" ENSG00000166479 "Thioredoxin related transmembrane protein 3" Q96JJ7 18 68673688-68715108 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014157 Uncertain "Intracellular and membrane" NA NA 36000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA014157: AB_1858469" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.14e-2)" "unprognostic (9.47e-2)" "unprognostic (6.82e-2)" "unprognostic (7.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (5.20e-2)" "unprognostic (9.83e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.69e-2)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" 22.7 16.2 11.7 24.1 13.0 14.1 19.2 14.2 15.4 15.0 9.9 12.7 18.2 16.6 20.4 14.1 13.8 16.5 20.8 13.5 13.2 14.6 16.2 19.5 27.9 11.1 11.2 13.0 11.9 15.9 9.6 19.8 12.1 17.7 16.3 26.0 10.6 13.0 11.0 16.7 18.8 21.0 11.4 22.6 14.0 11.4 12.1 23.3 17.7 21.0 22.7 20.1 11.2 11.5 11.1 17.4 32.9 25.9 66.6 70.7 24.5 85.7 91.0 61.0 67.7 8.4 31.9 31.4 16.6 125.4 25.9 40.8 21.9 42.9 92.8 30.3 19.6 28.8 27.4 14.7 70.6 62.0 45.7 56.5 27.1 66.2 59.2 61.8 78.4 27.0 18.9 42.5 73.1 6.9 33.3 19.6 13.9 9.1 28.2 30.7 65.5 38.5 51.7 24.2 31.5 24.5 42.0 26.7 31.8 32.4 17.6 52.1 76.4 108.4 30.0 24.7 63.6 28.4 30.4 29.4 65.5 50.1 81.3 2.2 2.9 2.4 3.8 4.7 5.5 3.1 3.9 3.6 4.7 2.1 4.3 4.4 0.7 4.9 3.3 6.4 4.4 2.7 11.7 13.0 14.2 15.4 13.5 13.2 11.1 11.2 12.1 11.4 12.1 11.5 31.4 28.9 27.8 36.2 25.0 20.3 17.2 17.6 12.0 29.1 21.0 15.6 25.1 10.0 18.8 16.5 18.8 15.0 44.3 10.6 1.9 15.2 8.9 18.7 38.5 27.3 18.0 17.0 77.9 10.2 20.8 34.5 13.3 25.6 20.3 24.2 34.2 26.6 18.6 26.9 45.6 13.8 14.2 23.3 26.8 3.3 24.2 23.9 24.9 32.8 18.2 20.5 20.6 49.8 53.1 15.4 15.4 16.6 29.8 19.4 17.5 8.0 28.8 32.5 39.5 23.6 32.0 23.8 28.3 21.7 24.3 12.4 23.3 22.9 9.4 16.6 TNFRSF11B "OCIF, OPG, TR1" ENSG00000164761 "TNF receptor superfamily member 11b" O00300 8 118923557-118951885 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 29.9;thyroid gland: 101.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 134.3;Collecting duct cells: 73.5;Ductal cells: 32.7;Proximal tubular cells: 117.3" "Cancer enhanced" "Detected in all" "renal cancer: 22.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 40 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 40 "dendritic cells: 3.9" "Group enriched" "Detected in many" 4 "BJ: 546.7;BJ hTERT+: 2013.0" "Low region specificity" "Detected in all" CAB034939 Approved "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "CAB034939: " "unprognostic (1.39e-2)" "prognostic unfavorable (6.22e-4)" "unprognostic (5.27e-2)" "unprognostic (2.33e-2)" "unprognostic (4.27e-3)" "unprognostic (1.10e-3)" "unprognostic (1.21e-3)" "unprognostic (5.50e-2)" "unprognostic (9.94e-2)" "unprognostic (6.32e-2)" "unprognostic (3.53e-2)" "unprognostic (2.43e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.32e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (3.88e-4)" 3.3 3.3 2.6 5.3 3.1 0.0 2.6 2.6 4.1 1.1 3.5 2.5 1.4 10.2 0.5 0.4 1.4 5.8 9.4 2.5 2.7 29.9 14.2 9.4 7.0 5.0 3.0 0.3 1.8 0.5 1.8 4.9 3.3 1.6 3.5 0.3 1.4 1.0 0.4 0.5 2.2 2.6 3.1 2.6 1.2 0.1 3.0 1.3 101.8 0.8 2.9 10.7 0.3 3.8 0.0 0.9 8.6 0.0 27.5 5.3 0.0 546.7 2013.0 25.9 7.2 6.3 1.1 0.0 143.7 302.4 0.0 5.6 0.0 0.0 13.2 0.1 0.0 0.0 23.1 0.0 3.6 0.0 0.0 2.9 0.0 26.7 0.0 10.9 0.3 0.0 0.0 0.0 73.8 13.6 0.0 0.1 0.9 2.6 3.3 0.0 1.0 0.0 23.6 0.0 1.3 0.0 4.8 0.2 0.0 0.3 0.0 0.1 1.2 16.9 8.6 10.1 1.2 0.6 0.0 0.1 2.3 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 2.6 3.1 2.6 4.1 2.5 2.7 5.0 3.0 3.3 3.1 3.0 3.8 2.1 3.2 0.0 7.2 0.7 2.2 0.6 1.4 0.0 0.2 134.3 4.1 3.8 22.8 1.0 73.5 0.0 0.0 0.2 2.5 9.8 32.7 0.1 0.6 1.4 7.4 9.5 0.0 0.8 1.3 0.2 9.4 0.0 1.7 0.0 0.0 4.6 2.0 0.5 0.0 0.3 9.2 2.0 0.3 3.9 0.3 0.3 1.1 0.0 0.0 8.3 1.2 0.0 3.0 0.3 9.2 0.8 0.0 0.0 6.8 1.1 117.3 0.1 0.1 0.0 0.4 4.3 0.1 0.3 0.0 1.1 0.0 0.4 0.0 2.8 0.3 TNFSF12-TNFSF13 TWE-PRIL ENSG00000248871 "TNFSF12-TNFSF13 readthrough" 17 7549099-7561601 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 9.1;choroid plexus: 5.7" "Group enriched" "Detected in some" 17 "Alveolar cells type 2: 3.7;Club cells: 3.7;granulocytes: 3.8;Macrophages: 4.5;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 7.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.7;fHDF/TERT166: 1.3;HUVEC TERT2: 1.1;U-138 MG: 1.7;U-251 MG: 1.7" "Low region specificity" "Detected in all" "HPA004863, HPA035984, HPA052967" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA004863: AB_1078187, HPA035984: , HPA052967: AB_2682000" "unprognostic (1.59e-1)" "unprognostic (1.48e-1)" "unprognostic (2.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "unprognostic (3.04e-1)" "unprognostic (2.19e-1)" "unprognostic (1.05e-2)" "unprognostic (1.40e-1)" "unprognostic (8.96e-3)" "unprognostic (1.38e-2)" "unprognostic (2.05e-1)" "unprognostic (8.23e-2)" 4.0 1.3 4.7 0.7 4.7 0.7 1.8 4.5 9.1 0.7 5.7 1.4 0.2 0.4 0.0 0.3 0.4 0.1 2.3 4.5 5.0 2.3 0.7 4.6 1.0 5.1 5.1 0.4 0.5 0.1 0.4 0.2 4.7 0.7 0.0 0.1 0.6 0.2 0.7 0.8 0.8 0.3 4.6 3.1 0.7 0.1 5.0 0.2 0.4 0.0 0.5 1.1 0.3 4.8 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.5 1.7 0.6 0.9 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.5 0.0 0.0 0.0 0.5 1.7 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.0 0.2 0.4 2.4 7.2 0.2 4.5 0.3 0.7 0.5 0.3 1.8 1.5 0.3 0.1 0.3 0.2 0.2 0.9 1.0 1.4 4.7 4.7 4.5 9.1 4.5 5.0 5.1 5.1 4.7 4.6 5.0 4.8 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TOR1A "DQ2, DYT1" ENSG00000136827 "Torsin family 1 member A" O14656 9 129812942-129824244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012473, HPA051195" Approved Supported "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 20000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Vesicles" "CAB012473: AB_2240792, HPA051195: AB_2681382" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.95e-1)" "unprognostic (1.86e-3)" "unprognostic (3.67e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.10e-2)" "unprognostic (1.41e-1)" "unprognostic (4.10e-2)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (3.39e-1)" "unprognostic (1.91e-1)" "unprognostic (1.77e-1)" "unprognostic (1.99e-1)" 21.2 24.2 14.3 20.7 14.8 34.5 19.6 14.7 17.7 18.6 14.2 20.7 16.6 20.3 19.9 14.3 17.2 20.6 16.8 15.7 15.9 20.5 35.9 19.4 22.9 13.6 14.0 17.2 19.5 19.4 14.3 23.5 14.0 21.3 22.3 9.8 17.0 23.1 16.4 17.8 18.8 25.4 14.1 18.8 18.1 9.2 15.4 26.3 23.8 14.9 19.0 28.6 15.6 14.8 33.7 49.5 35.9 41.5 53.1 51.3 47.4 76.7 94.5 67.0 57.2 32.3 48.2 41.0 44.0 99.7 46.0 77.2 34.7 50.8 54.7 65.7 32.9 36.9 49.8 32.3 66.9 82.1 65.5 69.8 50.7 63.5 45.6 61.5 73.2 65.3 66.5 32.3 74.6 84.3 58.9 79.3 53.8 39.2 55.6 30.5 56.5 41.9 54.9 42.4 27.0 47.6 79.3 30.7 43.3 40.1 61.6 63.4 65.1 66.1 37.7 49.6 59.6 36.6 87.0 37.7 49.0 46.9 54.3 95.5 72.8 141.3 57.4 68.5 48.1 45.5 48.4 52.1 61.4 33.5 40.9 42.4 72.7 68.6 58.3 56.5 59.1 78.9 14.3 14.8 14.7 17.7 15.7 15.9 13.6 14.0 14.0 14.1 15.4 14.8 25.0 9.6 11.8 5.5 17.5 17.6 16.6 39.5 12.0 11.2 16.5 15.9 9.9 18.6 24.4 14.7 2.1 47.9 39.3 18.7 15.6 42.1 0.7 12.5 18.8 24.2 19.2 30.5 6.3 49.9 65.7 25.0 13.7 15.0 22.2 23.4 16.1 22.7 45.2 21.9 6.4 17.8 26.4 19.1 22.4 1.3 12.8 27.9 14.2 3.7 47.6 18.5 35.0 9.5 6.6 40.1 18.9 15.4 23.7 24.7 21.0 17.0 14.9 9.2 32.9 15.2 24.3 7.3 10.1 9.3 18.5 53.4 25.5 23.4 15.4 19.6 TPGS2 "C18orf10, DKFZP586M1523, HsT3006" ENSG00000134779 "Tubulin polyglutamylase complex subunit 2" Q68CL5 18 36777647-36829216 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 499.2;Late spermatids: 1012.6;Spermatocytes: 318.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 266.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040596, HPA040617" Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA040596: AB_10796458, HPA040617: AB_10794037" "unprognostic (6.51e-3)" "prognostic favorable (4.09e-4)" "unprognostic (5.82e-2)" "unprognostic (1.18e-1)" "unprognostic (5.05e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (1.24e-5)" "unprognostic (3.78e-2)" "unprognostic (2.36e-1)" "prognostic favorable (1.93e-5)" "unprognostic (2.50e-2)" "unprognostic (1.33e-3)" "unprognostic (7.19e-3)" "unprognostic (2.51e-2)" "prognostic favorable (7.74e-4)" "unprognostic (4.03e-2)" "unprognostic (5.28e-2)" 44.8 52.7 65.8 29.5 70.4 70.2 40.2 68.8 71.3 44.8 169.7 40.1 27.2 37.4 32.5 56.8 54.7 43.5 58.9 71.4 82.7 46.2 27.2 48.6 38.8 80.9 89.1 67.6 35.2 41.1 23.0 35.4 92.2 34.2 41.0 58.4 32.6 34.8 16.4 46.4 34.5 48.4 65.3 24.9 31.9 202.9 68.6 101.3 49.6 22.1 64.6 54.1 37.7 69.9 142.4 109.6 208.8 183.2 102.3 111.0 87.6 152.7 207.6 210.6 252.9 53.2 99.6 138.8 104.0 307.5 133.5 138.1 173.9 215.3 246.9 182.2 59.0 97.2 186.5 145.8 104.9 126.5 83.1 148.9 110.0 188.0 96.6 202.5 253.6 142.1 143.1 100.0 279.9 84.0 202.2 74.0 126.8 62.8 70.9 149.4 192.8 169.6 235.3 136.8 146.5 160.3 229.8 59.4 67.6 181.4 114.1 120.6 143.0 210.6 78.1 30.3 123.6 126.5 129.4 164.4 170.3 101.3 120.9 266.1 44.0 89.5 44.2 50.3 44.4 44.7 51.4 46.2 45.1 31.5 38.5 43.5 13.5 52.3 61.0 35.8 94.3 52.8 65.8 70.4 68.8 71.3 71.4 82.7 80.9 89.1 92.2 65.3 68.6 69.9 26.2 44.8 34.7 9.4 23.7 28.9 39.3 87.8 25.6 21.5 38.2 42.5 19.7 54.3 64.1 25.8 8.4 81.2 25.6 13.9 72.4 123.2 499.2 68.8 27.1 32.0 19.8 125.8 27.1 77.2 144.5 41.3 25.0 50.7 19.0 41.6 36.8 21.7 85.8 8.4 30.9 24.5 69.2 29.9 32.4 1012.6 36.7 27.2 32.0 13.1 58.9 35.7 43.3 11.1 23.0 92.4 23.9 49.2 29.2 18.9 34.6 47.8 77.5 22.8 32.9 21.2 39.5 318.9 131.1 48.4 39.9 31.3 27.3 76.5 43.2 43.2 TPI1 ENSG00000111669 "Triosephosphate isomerase 1" P60174 12 6867119-6870948 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Glycolysis" "Isomerase, Lyase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2470.8;tongue: 2005.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050924, HPA053568" Uncertain Approved Nucleoplasm,Vesicles NA NA 170000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Vesicles "HPA050924: AB_2681276, HPA053568: AB_2682193" "unprognostic (2.85e-1)" "unprognostic (5.58e-3)" "unprognostic (1.65e-1)" "unprognostic (1.62e-2)" "unprognostic (6.94e-2)" "unprognostic (2.31e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (4.14e-3)" "unprognostic (7.49e-2)" "unprognostic (2.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (6.54e-4)" "unprognostic (7.04e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" 340.4 588.6 446.2 269.7 480.2 334.8 274.5 476.5 541.9 314.1 446.9 425.6 421.0 240.5 220.2 764.4 248.2 216.8 819.8 481.0 462.0 609.0 536.1 308.6 253.9 459.2 460.4 269.9 238.1 496.4 236.8 287.2 467.2 272.1 435.3 625.0 377.6 273.3 2470.8 410.1 404.5 301.5 429.7 291.4 329.0 239.8 503.5 200.3 269.1 2005.8 410.4 363.8 440.6 454.4 1556.8 1350.5 706.1 1094.6 666.5 696.6 1236.3 1097.5 1184.9 1999.1 2407.5 1409.9 823.0 903.4 212.7 1069.7 1042.4 748.8 1671.0 1812.3 2189.4 1196.4 1265.1 1172.0 924.4 926.2 496.8 1351.5 924.0 764.0 739.7 1537.8 1305.0 2816.1 1233.3 451.0 615.0 336.5 1554.5 1130.0 709.6 1119.5 1741.0 1302.3 855.9 413.5 1156.1 930.7 1261.4 1061.1 497.2 830.0 953.3 977.8 542.7 1452.6 224.4 1003.2 778.2 1068.0 914.6 703.1 1631.7 653.4 285.7 1327.8 2153.1 821.2 784.9 1708.8 2304.1 2375.2 824.6 2402.3 845.7 863.3 820.0 808.0 2656.1 800.9 570.5 703.0 934.3 1387.7 2165.7 482.0 1106.3 4679.5 446.2 480.2 476.5 541.9 481.0 462.0 459.2 460.4 467.2 429.7 503.5 454.4 311.5 134.6 204.2 34.6 290.6 684.8 553.8 1756.4 414.9 284.6 294.3 303.3 552.5 391.7 673.0 389.9 110.5 1017.0 278.2 850.3 1508.5 1361.5 203.0 280.8 307.0 352.0 425.5 243.3 38.4 786.5 1824.0 386.5 408.3 343.9 362.8 364.8 276.6 547.3 937.3 297.8 33.7 567.2 1151.5 386.7 750.4 683.5 279.0 482.8 674.1 18.7 1129.8 739.6 312.0 17.1 26.7 1081.5 889.4 263.3 427.9 556.2 1595.9 1642.7 401.2 298.0 197.2 270.5 551.3 14.9 79.0 690.4 615.9 1530.4 352.9 869.2 827.0 652.5 TPM2 "AMCD1, DA1, NEM4" ENSG00000198467 "Tropomyosin 2" P07951 9 35681992-35690056 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 39012.3;tongue: 16773.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1066.2;Peritubular cells: 2072.1;Sertoli cells: 2222.0;Smooth muscle cells: 2341.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 812 "plasmacytoid DC: 398.6" "Lineage enriched" "Detected in single" 920 "dendritic cells: 398.6" "Cell line enhanced" "Detected in many" "BJ: 2309.6;fHDF/TERT166: 1289.0;hTERT-RPE1: 1399.1" "HPA047089, HPA053624" Approved NA NA 140000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (5.56e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (2.64e-4)" "unprognostic (3.34e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-2)" "unprognostic (1.18e-3)" "unprognostic (6.56e-3)" "unprognostic (2.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.51e-10)" "unprognostic (1.43e-2)" "unprognostic (8.33e-2)" "unprognostic (5.52e-2)" "unprognostic (1.41e-2)" 331.1 285.0 88.0 411.0 89.8 16.7 260.8 92.5 117.3 651.3 127.3 3498.4 217.7 1928.1 201.9 1018.0 849.7 442.4 788.5 84.8 81.1 144.0 41.0 283.1 62.2 86.1 79.2 388.4 73.7 24.1 82.6 142.3 80.5 1219.0 238.0 8.0 393.6 1988.7 39012.3 148.5 636.2 2340.8 78.6 140.1 1252.6 82.9 83.3 26.3 138.9 16773.7 21.2 1630.1 454.9 79.8 375.4 291.2 213.9 33.6 335.4 893.3 129.3 2309.6 934.4 983.0 667.9 12.2 24.2 0.4 213.0 1289.0 144.6 9.2 3.7 291.2 457.0 716.2 10.8 9.1 1054.1 11.8 540.2 2.3 102.7 1067.7 44.9 738.8 0.4 1399.1 235.7 25.3 5.6 0.8 1052.1 15.3 2.7 29.1 269.6 1.5 17.0 18.5 391.5 3.0 31.1 7.2 3.8 13.3 470.0 7.9 18.2 273.8 6.8 27.7 30.0 16.5 585.7 11.6 730.6 0.6 2.7 2.9 34.0 6.5 29.2 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.3 0.4 0.0 0.1 0.0 0.4 0.2 0.0 398.6 0.0 2.1 88.0 89.8 92.5 117.3 84.8 81.1 86.1 79.2 80.5 78.6 83.3 79.8 110.0 3.2 4.1 10.4 5.9 57.1 81.2 274.1 24.5 0.8 29.9 1066.2 619.5 4.3 42.1 7.3 0.0 12.1 116.7 1.4 0.0 21.4 4.3 20.3 488.3 80.3 2.4 4.0 2.5 5.7 104.8 332.6 99.4 18.7 2.5 142.0 181.3 1.4 32.4 1.7 4.6 1.9 48.8 3.1 77.9 32.4 283.0 24.2 67.6 9.4 6.5 11.7 1.0 3.0 0.4 8.4 0.1 2072.1 2.9 169.8 0.4 1.3 23.5 0.9 2222.0 594.8 2341.4 2.5 27.3 6.7 42.8 14.6 16.0 106.7 2.8 28.7 TRHDE "PAP-II, PGPEP2, TRH-DE" ENSG00000072657 "Thyrotropin releasing hormone degrading enzyme" Q9UKU6 12 72087266-72670758 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.6;pancreas: 10.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 216.9;Inhibitory neurons: 292.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.9" "Group enriched" "Detected in many" 5 "basal ganglia: 4.9;cerebellum: 4.4;cerebral cortex: 2.5;hippocampal formation: 7.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 30.3;BJ hTERT+: 29.1;EFO-21: 15.3;HBF TERT88: 10.3;hTERT-RPE1: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 7300000 "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.56e-2)" "unprognostic (4.06e-3)" "unprognostic (6.01e-2)" "unprognostic (1.44e-6)" "unprognostic (1.77e-1)" "unprognostic (6.37e-2)" "unprognostic (7.79e-2)" "unprognostic (6.96e-2)" "unprognostic (3.99e-2)" "unprognostic (1.48e-1)" "unprognostic (5.14e-4)" "unprognostic (2.40e-1)" "prognostic favorable (1.53e-7)" "unprognostic (2.55e-2)" "unprognostic (2.48e-1)" "unprognostic (8.91e-3)" "unprognostic (2.94e-2)" 3.6 0.9 0.1 0.3 4.9 0.4 0.8 4.4 2.5 3.7 0.0 1.1 2.4 1.2 0.6 0.2 1.1 0.8 0.8 7.6 0.0 5.1 0.5 1.4 0.1 0.0 0.9 3.2 10.3 0.0 0.1 0.1 0.0 1.3 0.5 0.8 0.8 2.8 0.2 0.2 2.1 0.4 0.0 2.5 0.3 0.7 0.0 0.1 0.0 0.4 0.3 1.2 2.3 0.0 3.6 0.0 0.6 0.0 1.6 0.0 9.5 30.3 29.1 2.9 1.9 0.0 0.0 0.0 15.3 4.3 3.0 0.4 5.4 0.0 10.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 2.3 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 8.7 0.0 0.0 0.0 9.5 6.7 2.9 0.1 0.0 0.0 0.0 0.5 0.0 5.7 0.0 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.9 4.4 2.5 7.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.5 2.9 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.9 1.5 0.0 1.8 0.0 0.1 0.0 7.1 3.9 0.0 35.9 0.1 0.4 0.2 0.0 0.0 216.9 2.6 0.4 4.7 0.0 0.3 0.0 0.1 0.4 1.4 0.2 0.0 292.7 3.5 0.0 0.0 0.0 62.8 29.5 0.7 0.0 2.8 0.0 0.4 0.0 38.2 4.0 2.2 3.9 13.5 0.0 0.2 15.8 9.1 0.7 0.6 0.0 37.4 0.6 0.2 0.7 0.0 0.0 0.1 0.1 0.2 1.6 0.1 TRIOBP "DFNB28, HRIHFB2122, KIAA1662, TAP68, Tara" ENSG00000100106 "TRIO and F-actin binding protein" Q9H2D6 22 37697048-37776556 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003747, HPA019769" Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA003747: AB_1858328, HPA019769: AB_1858329" "unprognostic (2.94e-1)" "prognostic favorable (4.29e-4)" "unprognostic (2.79e-1)" "unprognostic (4.57e-2)" "unprognostic (8.22e-2)" "unprognostic (7.44e-3)" "unprognostic (3.77e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (5.56e-2)" "unprognostic (2.40e-1)" "unprognostic (1.99e-1)" "unprognostic (4.38e-3)" "unprognostic (1.31e-1)" "unprognostic (2.81e-1)" "unprognostic (3.20e-2)" "unprognostic (1.67e-2)" 56.3 46.5 15.4 27.3 16.6 25.7 50.8 14.7 14.9 73.1 22.1 70.6 23.9 71.8 12.8 78.5 66.1 27.8 74.6 12.8 13.2 37.2 21.6 51.6 17.4 20.0 17.2 55.7 32.7 31.1 16.9 44.2 16.5 45.3 17.0 4.8 44.3 33.3 24.3 32.0 38.0 31.0 16.6 53.1 53.6 26.1 16.9 16.7 48.2 14.3 12.5 66.5 65.7 17.3 65.9 53.1 33.2 26.4 73.1 118.1 47.5 113.0 111.9 57.7 42.1 11.8 44.8 24.5 30.4 69.6 31.6 52.7 9.2 63.7 18.1 39.6 29.1 6.8 41.6 22.4 75.5 32.1 28.9 47.1 29.8 52.0 24.5 125.3 71.9 20.6 6.4 34.6 45.5 39.3 14.4 23.1 20.2 65.4 63.2 25.1 23.9 17.2 41.0 52.8 16.2 25.4 50.9 46.5 59.7 32.8 25.4 23.0 151.9 87.2 38.6 60.6 27.0 30.4 9.1 15.4 82.7 13.0 104.3 7.7 7.6 12.2 1.8 7.5 0.6 1.3 1.5 1.8 4.1 2.4 1.2 1.8 18.2 1.9 12.5 1.9 2.5 2.0 15.4 16.6 14.7 14.9 12.8 13.2 20.0 17.2 16.5 16.6 16.9 17.3 102.0 19.2 29.7 17.9 10.7 6.2 48.3 18.3 18.8 22.8 40.1 45.1 65.2 62.9 23.3 58.8 2.1 105.7 14.7 63.8 15.6 42.7 30.3 32.6 107.0 91.6 22.9 28.2 4.7 51.6 34.2 65.5 58.1 34.2 6.3 128.1 124.6 17.1 42.7 16.8 4.6 52.1 6.1 56.0 7.5 10.6 113.1 31.2 14.2 27.2 32.0 29.6 8.2 7.5 14.0 62.8 46.9 92.2 9.5 41.9 24.8 15.8 23.9 7.3 52.6 17.7 31.8 49.8 23.4 57.2 6.1 116.0 12.7 22.5 40.6 57.9 TRMT9B "C8orf79, FLJ36980, hTRM9L, KIAA1456, TRM9L" ENSG00000250305 "TRNA methyltransferase 9B (putative)" Q9P272 8 12945642-13031503 "Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 118.6;choroid plexus: 375.5" "Cell type enhanced" "Detected in some" "Club cells: 9.9;Collecting duct cells: 14.7;Distal tubular cells: 11.7;Endometrial ciliated cells: 35.1;Glandular and luminal cells: 18.7;Respiratory ciliated cells: 14.6" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.2" "Region enriched" "Detected in all" 5 "cerebellum: 118.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.0;BJ: 8.7;fHDF/TERT166: 11.9;RPTEC TERT1: 4.0;SCLC-21H: 4.3;U-266/84: 4.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 31.1" HPA024673 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA024673: AB_1845788" "unprognostic (9.85e-3)" "unprognostic (1.20e-1)" "unprognostic (5.54e-4)" "unprognostic (1.06e-2)" "unprognostic (4.08e-2)" "unprognostic (1.31e-2)" "unprognostic (1.64e-1)" "unprognostic (1.44e-1)" "unprognostic (1.93e-1)" "unprognostic (8.89e-2)" "unprognostic (1.96e-2)" "unprognostic (1.88e-1)" "prognostic favorable (2.77e-7)" "unprognostic (2.22e-1)" "unprognostic (4.63e-2)" "unprognostic (4.27e-3)" "unprognostic (3.34e-2)" 1.3 0.4 6.1 0.6 6.8 0.3 2.3 118.6 7.9 1.7 375.5 1.6 0.7 1.0 0.9 0.9 2.0 1.6 6.3 25.2 6.3 3.5 2.2 1.7 0.4 5.4 7.2 0.3 2.2 1.6 1.4 0.4 11.5 1.2 1.2 24.5 2.6 1.0 3.2 3.2 1.2 0.4 4.8 1.5 1.1 1.2 17.5 0.2 33.7 1.6 0.3 0.9 0.8 5.0 0.1 0.0 6.0 0.0 0.0 0.0 1.4 8.7 2.0 1.2 0.6 0.0 0.1 0.1 0.4 11.9 1.1 0.2 0.1 0.2 1.2 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.6 0.2 3.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.3 0.0 0.1 0.7 0.1 0.0 1.0 0.0 0.1 4.0 0.1 4.3 0.1 0.0 0.0 0.1 1.9 0.1 0.0 0.0 0.1 0.8 0.8 0.1 0.2 4.4 0.0 0.0 0.0 1.5 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 6.1 6.8 118.6 7.9 25.2 6.3 5.4 7.2 11.5 4.8 17.5 5.0 6.2 6.4 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.1 6.7 0.0 0.0 9.9 14.7 0.0 1.0 0.2 0.0 11.7 2.3 0.0 35.1 6.4 2.1 0.0 0.0 0.0 1.1 0.2 1.8 0.0 18.7 1.3 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.3 14.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 TRPC4 "HTRP4, TRP4" ENSG00000133107 "Transient receptor potential cation channel subfamily C member 4" Q9UBN4 13 37632063-37869802 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 11.9;seminal vesicle: 9.0;smooth muscle: 12.6" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 133.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.7;BJ: 20.2;BJ hTERT+ SV40 Large T+: 9.1;fHDF/TERT166: 19.6;U-2197: 9.3" "Region enhanced" "Detected in many" "basal ganglia: 43.1" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (4.52e-4)" "unprognostic (9.99e-2)" "unprognostic (5.42e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-1)" "unprognostic (2.57e-1)" "unprognostic (3.28e-1)" "unprognostic (1.60e-1)" "unprognostic (5.10e-2)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (3.95e-2)" "unprognostic (1.07e-6)" "unprognostic (3.73e-3)" "unprognostic (1.93e-2)" "unprognostic (3.24e-1)" "unprognostic (1.43e-2)" 0.8 0.4 2.9 0.8 7.1 0.0 0.3 0.0 3.5 2.5 0.0 3.1 0.4 11.9 0.8 0.1 1.3 3.3 1.2 4.7 5.4 1.8 0.2 3.4 0.1 0.9 2.6 2.7 1.3 0.2 0.2 1.3 0.6 6.7 0.6 0.2 0.2 9.0 0.2 0.1 1.0 12.6 0.6 0.2 2.0 0.1 2.5 0.0 0.7 0.2 0.0 1.6 1.6 1.2 0.0 0.0 8.7 0.0 1.2 2.6 0.0 20.2 2.9 9.1 4.4 0.0 0.3 0.0 0.0 19.6 3.1 0.0 0.1 0.0 4.2 0.0 0.1 0.0 0.4 0.0 3.1 0.0 0.0 1.3 0.0 2.6 0.0 1.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.2 0.1 9.3 1.8 4.7 1.2 0.0 1.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 7.1 0.0 3.5 4.7 5.4 0.9 2.6 0.6 0.6 2.5 1.2 0.3 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.3 12.3 0.6 0.0 0.0 32.0 0.0 0.0 3.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 133.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 15.0 0.0 0.0 0.0 2.5 1.4 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.2 7.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 TSPAN5 "NET-4, TM4SF9, Tspan-5" ENSG00000168785 "Tetraspanin 5" P62079 4 98470367-98658611 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 175.4;Excitatory neurons: 362.2;Inhibitory neurons: 248.3;Microglial cells: 195.8;Oligodendrocytes: 587.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 37 "B-cells: 3.0;NK-cells: 3.8;T-cells: 6.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 120.8;BJ hTERT+: 121.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (2.29e-1)" "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" "unprognostic (2.00e-3)" "unprognostic (2.65e-1)" "unprognostic (2.44e-3)" "unprognostic (1.41e-2)" "unprognostic (1.54e-2)" "unprognostic (9.27e-2)" "unprognostic (1.79e-1)" "unprognostic (3.30e-3)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.83e-5)" "prognostic unfavorable (8.56e-4)" "unprognostic (2.15e-1)" "unprognostic (3.23e-3)" "unprognostic (1.23e-1)" 2.7 1.2 32.5 3.8 37.2 10.4 15.4 62.0 42.7 13.5 21.6 6.4 1.5 19.9 29.2 12.9 7.2 5.0 3.2 41.4 33.5 5.1 0.6 4.3 6.7 32.8 30.8 46.4 0.9 4.0 5.1 7.9 34.5 5.3 3.8 28.1 10.8 8.7 3.8 20.0 3.0 16.4 32.4 9.9 8.9 12.6 33.7 8.5 18.5 3.2 9.2 8.8 9.7 47.4 27.8 10.8 11.0 0.7 41.2 120.8 3.7 111.9 121.4 39.4 48.3 9.6 14.6 0.0 1.1 40.2 21.6 7.0 9.6 52.6 87.7 34.3 5.2 16.9 1.5 0.4 42.5 9.5 0.9 70.1 1.6 72.5 89.1 60.5 64.5 11.3 6.6 29.1 95.3 0.7 29.1 0.1 7.2 23.8 49.2 8.8 10.5 4.2 3.5 8.1 77.5 14.8 2.0 35.4 0.2 3.7 1.2 1.4 66.4 82.7 37.4 29.8 39.9 20.0 31.8 0.0 32.4 22.5 28.8 0.0 0.0 0.0 3.3 0.0 3.6 1.3 4.7 4.7 0.1 3.0 2.4 1.6 0.1 3.8 0.0 0.0 6.0 1.1 32.5 37.2 62.0 42.7 41.4 33.5 32.8 30.8 34.5 32.4 33.7 47.4 4.6 22.4 9.1 129.3 5.6 22.0 24.8 9.1 10.8 63.9 30.9 26.0 2.3 0.0 9.3 29.5 27.1 1.0 17.2 1.4 5.9 2.3 69.6 8.5 45.9 19.7 80.9 175.4 362.2 7.1 0.9 26.0 10.2 15.1 2.5 11.6 8.2 0.9 2.3 111.0 248.3 4.6 20.3 3.4 15.4 91.4 46.0 7.1 28.4 195.8 0.3 21.5 39.1 94.5 587.2 25.3 0.5 17.0 9.3 45.9 0.4 0.6 3.7 41.9 6.6 9.7 13.1 10.1 4.1 33.0 57.7 2.9 31.4 79.7 3.8 44.8 TSPYL4 "dJ486I3.2, KIAA0721" ENSG00000187189 "TSPY like 4" Q9UJ04 6 116249964-116254075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA044863 Approved NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA044863: AB_10962578" "unprognostic (5.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.79e-1)" "unprognostic (1.65e-3)" "unprognostic (1.67e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (1.80e-2)" "unprognostic (3.34e-1)" "unprognostic (7.41e-3)" "prognostic favorable (8.46e-5)" "unprognostic (1.30e-1)" "prognostic favorable (5.13e-7)" "unprognostic (3.34e-3)" "unprognostic (2.57e-1)" "unprognostic (3.61e-1)" "unprognostic (5.38e-2)" 8.2 35.4 57.5 7.5 61.8 10.4 14.0 56.2 109.7 17.1 15.5 12.3 5.8 21.5 18.0 11.6 21.0 10.6 20.4 62.8 72.8 14.9 9.0 10.2 10.3 44.9 55.9 25.4 12.2 28.7 28.4 10.7 60.0 22.4 8.1 30.1 9.6 18.5 5.1 10.5 9.3 15.4 43.1 11.0 15.3 14.8 69.5 17.7 14.3 7.8 9.2 11.8 11.9 48.5 6.2 3.4 47.6 39.7 19.2 16.4 8.9 24.3 16.4 30.6 18.2 9.6 5.9 5.0 9.0 37.5 16.1 13.6 20.7 21.6 45.8 20.7 7.0 10.1 18.8 22.7 15.1 19.1 6.4 16.0 10.0 23.7 12.0 23.9 21.0 28.0 15.7 16.4 25.7 19.2 36.9 11.7 11.5 2.1 8.1 20.9 2.6 4.9 9.2 9.0 55.9 37.6 21.6 9.0 4.3 16.9 16.3 10.5 24.4 25.4 21.3 14.6 14.1 6.6 8.2 0.8 11.7 12.5 16.2 0.5 2.1 2.5 3.2 1.8 3.8 2.4 3.9 3.3 1.9 3.0 4.1 3.1 2.8 3.8 2.8 3.1 3.6 4.0 57.5 61.8 56.2 109.7 62.8 72.8 44.9 55.9 60.0 43.1 69.5 48.5 7.0 3.2 7.7 11.8 9.2 4.8 11.9 4.9 30.1 21.4 11.8 13.2 44.2 11.5 7.2 11.0 20.9 3.3 13.0 3.2 19.6 5.4 20.3 30.8 31.9 11.5 31.7 6.1 16.2 7.4 2.0 13.3 8.6 25.8 11.4 27.5 11.7 3.7 3.6 40.4 16.8 5.8 6.1 6.8 3.5 6.7 10.2 8.8 5.4 7.5 5.9 20.7 6.2 4.5 8.5 7.1 2.5 10.9 7.3 7.0 0.7 6.4 27.5 28.7 0.0 14.8 16.8 20.1 3.6 14.1 5.3 3.4 11.9 18.9 4.5 8.0 TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 190.2;Extravillous trophoblasts: 494.3;Pancreatic endocrine cells: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.3" "Group enriched" "Detected in many" 6 "B-cells: 58.7;dendritic cells: 157.3" "Cell line enhanced" "Detected in many" "TIME: 821.6" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 10.3" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 52000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.40e-2)" "unprognostic (8.28e-3)" "unprognostic (1.22e-2)" "unprognostic (5.20e-3)" "unprognostic (8.42e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-2)" "unprognostic (4.95e-2)" "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (5.83e-3)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (9.69e-4)" 197.9 37.9 12.3 82.1 11.7 34.8 134.6 14.7 14.6 106.5 28.6 193.6 31.4 173.5 24.9 217.5 121.2 66.4 166.2 11.8 13.7 66.0 40.8 92.9 31.6 19.2 16.3 81.2 52.7 5.6 33.1 59.7 15.1 84.2 28.8 3.6 69.6 91.3 37.3 78.2 75.8 151.9 14.1 34.0 89.1 28.3 18.4 12.2 52.2 20.2 31.3 129.9 124.2 12.5 211.8 142.3 149.5 76.1 149.0 208.8 108.1 648.5 424.2 492.0 459.1 113.0 65.2 1.3 281.7 440.8 148.6 99.5 84.7 653.6 380.6 1.8 46.1 32.3 159.2 73.6 151.0 2.7 59.5 219.1 146.0 429.4 222.7 148.8 366.1 12.5 159.7 2.5 432.5 216.1 0.8 162.4 79.1 3.3 70.0 1.6 260.0 2.2 99.7 5.8 19.3 27.2 360.3 34.8 113.9 153.7 76.5 203.8 821.6 600.0 510.6 565.7 574.2 11.5 3.8 3.8 458.9 46.9 219.8 2.0 19.4 0.3 0.6 7.6 0.3 42.0 0.1 0.2 25.5 58.7 0.2 0.3 0.4 0.9 7.5 157.3 0.2 13.2 12.3 11.7 14.7 14.6 11.8 13.7 19.2 16.3 15.1 14.1 18.4 12.5 67.0 83.3 7.9 0.7 16.1 69.6 42.7 151.4 16.5 1.2 30.4 44.8 54.3 8.6 37.4 7.3 0.0 53.8 23.6 0.6 1.9 167.6 190.2 6.4 76.9 128.9 0.0 12.2 0.8 104.9 494.3 112.8 1.5 7.1 45.6 7.4 82.5 0.4 69.4 0.0 0.6 0.4 42.7 13.2 85.2 114.9 70.2 36.5 33.8 12.2 65.9 0.2 0.0 0.5 0.4 221.1 0.1 91.4 1.0 51.5 0.1 1.2 18.2 1.6 26.3 89.2 130.5 4.3 6.3 55.7 66.9 22.2 3.6 9.5 0.5 65.2 TUSC3 "MagT2, MGC13453, MRT22, MRT7, N33, OST3A, SLC58A2" ENSG00000104723 "Tumor suppressor candidate 3" Q13454 8 15417215-15766649 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 472.9;Extravillous trophoblasts: 321.8;Syncytiotrophoblasts: 783.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049851, HPA049974" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA049851: AB_2680913, HPA049974: AB_2680976" "unprognostic (3.31e-2)" "unprognostic (7.17e-2)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (4.46e-1)" "unprognostic (2.34e-1)" "unprognostic (7.15e-3)" "unprognostic (5.02e-2)" "unprognostic (7.39e-2)" "unprognostic (4.79e-2)" "unprognostic (1.59e-3)" "unprognostic (4.81e-1)" "unprognostic (1.60e-3)" "unprognostic (5.99e-3)" "unprognostic (1.17e-1)" "prognostic favorable (7.86e-4)" "unprognostic (1.55e-1)" 23.3 68.8 18.7 8.4 18.4 0.1 28.3 22.3 17.1 25.0 46.6 14.5 9.3 31.9 100.8 11.8 57.6 16.7 34.9 17.1 48.2 25.2 6.9 18.4 6.8 8.9 11.6 73.6 35.0 54.0 69.6 80.5 8.9 46.4 15.5 40.9 12.1 29.7 4.5 8.2 8.2 32.5 7.7 5.3 10.8 23.2 21.0 7.5 9.5 5.7 5.6 34.0 13.0 8.0 52.1 38.4 104.3 96.7 125.2 126.7 0.2 74.9 168.8 85.2 139.3 0.1 0.1 0.7 24.5 105.9 92.4 39.3 37.5 76.1 116.0 0.1 49.8 0.0 30.1 6.0 51.9 0.2 5.6 111.8 22.8 121.0 43.1 113.7 6.9 15.9 70.9 15.6 123.2 41.2 20.6 0.4 49.2 0.0 33.5 24.8 88.7 0.3 108.3 127.1 40.7 74.6 0.0 40.6 56.5 76.2 49.8 0.2 29.0 71.9 71.3 31.3 36.5 0.0 10.0 0.4 1.2 0.0 102.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 18.4 22.3 17.1 17.1 48.2 8.9 11.6 8.9 7.7 21.0 8.0 88.6 0.0 10.3 13.4 0.6 9.9 61.1 123.5 63.7 50.4 40.0 52.1 47.5 18.6 47.0 79.1 8.4 472.9 0.9 2.1 17.6 179.0 11.5 100.8 48.6 36.2 95.7 0.0 141.0 12.2 321.8 53.4 7.7 35.0 1.3 39.3 7.5 0.0 41.8 32.0 155.3 26.3 95.6 0.0 6.3 7.6 34.8 1.5 24.9 24.4 1.6 35.9 0.0 61.3 3.9 23.8 4.1 23.0 2.6 63.8 0.0 23.7 172.4 28.1 39.5 2.0 49.7 60.9 47.4 26.2 4.1 783.8 1.6 46.6 7.8 51.4 TWF1 "A6, PTK9" ENSG00000151239 "Twinfilin actin binding protein 1" Q12792 12 43793723-43806328 "Disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018116 Approved Supported Cytosol NA NA 75000 "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA018116: AB_1855899" "unprognostic (3.06e-1)" "unprognostic (1.95e-2)" "prognostic favorable (8.29e-4)" "unprognostic (7.39e-3)" "unprognostic (2.35e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (5.19e-2)" "unprognostic (1.13e-2)" "unprognostic (7.30e-2)" "unprognostic (3.11e-3)" "unprognostic (2.51e-1)" "unprognostic (8.48e-2)" "unprognostic (1.03e-1)" "unprognostic (2.19e-1)" "unprognostic (2.95e-1)" "unprognostic (2.62e-1)" 45.2 40.2 27.9 39.0 33.0 46.2 49.4 30.6 38.9 54.8 27.2 65.9 68.7 39.9 48.5 93.8 45.3 48.7 13.1 26.5 32.5 51.2 53.9 24.9 30.5 32.5 30.9 27.1 39.0 39.9 23.9 35.0 32.6 46.0 65.7 32.5 42.5 73.5 5.8 36.7 67.8 46.6 31.8 20.2 46.1 20.1 30.8 24.4 73.1 11.7 34.2 74.6 38.0 37.2 121.3 88.5 45.1 55.5 115.8 132.5 109.3 165.3 136.1 131.7 99.2 143.3 165.2 32.5 150.0 159.6 77.3 79.8 62.6 118.2 186.1 11.3 72.5 30.2 68.6 67.7 93.9 35.0 37.6 91.0 94.4 136.8 152.0 167.5 117.0 16.1 33.4 35.9 207.4 64.8 16.8 24.1 27.5 0.0 142.7 14.1 51.1 36.8 175.9 149.1 33.3 50.0 138.2 123.7 121.7 62.8 116.2 34.4 113.0 161.5 107.1 130.8 139.8 31.1 32.9 44.4 148.8 89.0 62.6 10.2 2.6 5.7 5.1 4.1 5.9 6.1 6.0 6.6 4.1 3.0 5.9 6.7 4.4 12.1 4.4 2.7 6.6 3.2 27.9 33.0 30.6 38.9 26.5 32.5 32.5 30.9 32.6 31.8 30.8 37.2 40.7 12.8 33.8 6.2 24.7 41.7 33.3 32.6 42.1 22.7 43.9 30.6 6.0 30.0 40.3 35.0 20.9 41.5 36.2 92.8 41.1 50.9 20.6 70.9 40.3 32.0 44.9 7.8 10.1 79.7 58.0 32.4 53.0 53.6 5.1 27.7 24.3 28.7 26.9 20.2 10.3 45.2 48.8 30.0 20.9 10.8 26.8 24.7 35.6 8.4 17.7 33.5 14.4 10.1 15.7 74.9 77.4 32.0 34.0 57.5 66.3 68.7 53.5 32.9 26.3 25.4 41.7 11.7 22.1 95.0 51.1 85.0 25.8 39.6 61.8 74.9 TWIST2 "bHLHa39, Dermo-1, DERMO1" ENSG00000233608 "Twist family bHLH transcription factor 2" Q8WVJ9 2 238848032-238910534 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 95.4;Fibroblasts: 58.9;Leydig cells: 48.1;Peritubular cells: 39.1;Theca cells: 23.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 24 "eosinophil: 4.6" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "ASC diff: 80.0;ASC TERT1: 50.5;BJ: 69.3;BJ hTERT+: 212.4;fHDF/TERT166: 97.4;U-2197: 81.3" "Low region specificity" "Detected in single" HPA062870 Supported Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Nucleoli "HPA062870: AB_2684888" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.83e-2)" "unprognostic (4.06e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-2)" "unprognostic (2.33e-1)" "unprognostic (2.24e-1)" "unprognostic (1.17e-1)" "unprognostic (2.40e-9)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.98e-2)" "unprognostic (4.48e-2)" 59.7 4.0 0.3 1.4 0.3 0.4 43.3 0.3 0.5 83.0 0.6 22.9 0.3 31.3 0.7 10.1 30.4 1.7 10.8 0.4 0.3 1.8 0.7 9.3 0.3 0.4 0.8 39.9 1.8 0.1 8.3 3.1 0.4 25.7 1.1 0.0 7.9 3.7 1.8 33.5 8.9 2.9 0.4 2.3 10.3 1.9 0.3 0.1 8.2 1.0 0.4 21.3 54.2 0.5 0.1 4.5 0.4 0.0 80.0 50.5 0.1 69.3 212.4 31.0 46.4 0.0 0.0 0.0 2.1 97.4 2.5 0.5 0.7 5.4 22.5 0.0 7.3 0.0 4.0 0.2 13.7 0.0 1.6 11.8 2.9 15.0 12.5 3.7 4.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.7 0.0 0.9 11.8 1.2 2.2 81.3 0.8 0.0 0.0 0.0 0.3 2.1 4.3 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.4 0.3 0.4 0.8 0.4 0.4 0.3 0.5 2.5 0.0 2.6 0.0 0.1 2.0 16.0 0.0 7.4 0.0 0.5 0.4 0.6 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.4 3.6 95.4 1.3 0.0 0.0 4.4 0.0 1.9 58.9 0.0 2.1 1.3 0.5 2.9 0.1 2.2 0.0 0.2 0.0 0.0 0.0 3.6 1.2 48.1 0.8 1.8 12.2 0.4 0.0 8.2 0.5 0.1 0.1 0.0 39.1 0.0 20.5 0.0 0.0 0.0 0.0 0.0 1.1 9.6 0.5 3.3 0.2 1.7 1.6 1.6 23.2 0.0 3.7 TWSG1 TSG ENSG00000128791 "Twisted gastrulation BMP signaling modulator 1" Q9GZX9 18 9334767-9402420 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 141.2;Peritubular cells: 95.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014898 Uncertain Supported Centrosome,Cytosol "Secreted - unknown location" No No 3500000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Centrosome, Cytosol" "HPA014898: AB_1858467" "unprognostic (2.55e-1)" "unprognostic (3.17e-2)" "unprognostic (7.31e-2)" "unprognostic (8.95e-3)" "unprognostic (2.92e-3)" "unprognostic (1.83e-1)" "unprognostic (8.29e-2)" "unprognostic (5.88e-2)" "unprognostic (6.33e-2)" "unprognostic (1.05e-2)" "unprognostic (3.10e-2)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (4.36e-2)" "unprognostic (8.73e-2)" "unprognostic (1.79e-1)" "unprognostic (1.32e-2)" 23.7 19.5 7.7 16.7 9.6 8.2 17.5 9.2 12.2 40.6 12.7 22.1 11.1 51.3 45.8 26.1 30.5 36.3 18.6 7.4 9.2 36.3 10.0 19.7 11.8 10.5 9.4 32.3 9.7 33.2 9.8 24.8 10.4 43.0 22.4 5.7 11.1 64.6 5.7 12.9 12.5 80.1 9.7 13.6 14.9 11.8 8.9 7.0 34.9 16.5 14.9 34.7 16.2 11.0 57.3 19.9 57.6 28.6 111.2 99.7 26.6 107.2 132.4 57.6 81.9 21.2 73.5 8.2 52.7 142.5 37.4 19.5 57.1 42.4 105.3 22.0 15.4 14.7 15.9 10.8 98.7 10.8 29.4 102.0 34.1 48.3 23.3 78.7 90.8 7.8 22.7 14.6 149.2 17.0 11.9 13.2 18.9 33.6 16.1 20.7 58.7 5.0 65.7 75.2 7.4 20.0 83.3 23.1 22.9 23.9 26.1 25.0 75.6 104.9 52.4 99.5 67.5 21.2 20.1 15.1 64.5 14.9 37.9 8.3 2.7 4.0 4.3 1.5 2.8 2.1 2.0 4.5 5.5 1.6 2.3 4.8 1.2 2.9 0.5 5.3 1.0 2.1 7.7 9.6 9.2 12.2 7.4 9.2 10.5 9.4 10.4 9.7 8.9 11.0 9.0 25.6 18.4 13.1 8.1 39.6 21.3 18.5 51.2 4.8 18.5 11.6 7.8 10.0 21.0 75.4 0.0 6.3 12.1 12.1 1.9 9.1 141.2 13.3 38.6 18.1 6.0 9.9 28.0 7.6 18.3 61.9 10.2 23.4 6.3 31.6 17.2 7.5 16.0 3.3 31.0 8.2 57.0 9.4 30.1 30.7 37.6 12.2 23.2 17.8 15.3 16.1 7.2 29.1 31.6 9.2 10.7 95.2 17.8 46.3 1.3 12.6 12.4 5.0 72.3 28.9 56.6 24.6 9.6 26.6 26.9 4.7 10.1 20.4 12.2 27.1 TXNDC9 APACD ENSG00000115514 "Thioredoxin domain containing 9" O14530 2 99318982-99340702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031844, HPA031845, HPA031846" Approved Enhanced Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA031844: AB_10600838, HPA031845: AB_10670968, HPA031846: AB_10669916" "unprognostic (3.63e-3)" "unprognostic (4.26e-2)" "unprognostic (7.28e-2)" "unprognostic (3.12e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (9.63e-7)" "unprognostic (2.06e-2)" "unprognostic (9.09e-2)" "unprognostic (1.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.32e-1)" "unprognostic (2.47e-3)" "unprognostic (2.03e-1)" "unprognostic (1.14e-1)" "unprognostic (1.29e-1)" 18.7 17.9 10.0 21.3 10.8 17.5 28.7 11.0 13.2 19.3 10.4 24.6 18.4 16.6 25.9 26.1 18.1 18.6 28.6 10.8 11.7 28.8 27.2 20.1 29.2 11.6 11.5 10.7 10.9 15.4 11.3 23.5 11.9 19.6 26.3 11.0 15.1 16.1 18.2 19.0 17.6 24.4 11.8 18.6 18.5 17.8 10.9 26.1 24.8 16.2 34.0 24.9 14.1 12.5 78.3 27.6 55.0 27.7 55.8 57.8 65.8 83.1 79.5 88.5 85.0 71.1 55.5 58.0 66.9 72.6 77.0 52.7 55.2 88.2 102.6 44.0 53.5 60.4 34.5 77.0 54.2 71.8 44.2 53.0 76.7 74.3 53.8 46.1 101.9 32.1 73.0 51.1 103.7 41.5 43.4 63.6 43.4 46.4 68.7 32.5 53.0 56.4 123.9 62.6 37.1 31.5 41.7 56.2 93.7 69.8 64.3 60.9 69.4 65.1 62.7 40.6 62.6 21.2 37.1 65.6 51.9 76.8 58.6 110.6 54.1 61.1 56.7 60.5 70.2 69.1 66.6 64.4 60.3 57.6 61.9 62.5 53.5 77.7 82.6 60.9 91.2 87.0 10.0 10.8 11.0 13.2 10.8 11.7 11.6 11.5 11.9 11.8 10.9 12.5 46.6 9.6 13.4 8.8 33.4 35.2 29.7 137.1 25.0 11.3 21.5 26.3 27.6 25.8 67.0 36.8 8.4 75.7 31.3 26.2 84.1 79.8 75.7 37.3 29.9 46.2 20.9 47.8 13.3 69.4 82.5 29.2 22.4 25.5 17.7 21.0 38.2 24.4 56.9 13.5 12.8 25.7 91.6 25.4 31.3 21.1 27.7 30.2 26.6 4.7 55.5 26.9 44.3 12.5 16.7 84.5 21.6 23.3 31.8 24.0 21.9 121.5 72.8 19.8 26.3 17.8 89.3 52.8 42.7 29.4 38.9 81.3 35.1 40.1 26.6 21.9 TXNRD1 "GRIM-12, Trxr1, TXNR" ENSG00000198431 "Thioredoxin reductase 1" Q16881 12 104215779-104350307 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 459.7;Prostatic glandular cells: 557.4;Urothelial cells: 488.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 1452.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001395, CAB004607, CAB015834, HPA043871" Approved Supported Nucleoplasm NA NA 6100000 "Cluster 46: Basophils - DNA binding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB004607: AB_628405, CAB015834: , HPA001395: AB_1858377, HPA043871: AB_2678709" "unprognostic (2.52e-2)" "unprognostic (1.16e-1)" "unprognostic (5.48e-2)" "unprognostic (1.01e-1)" "unprognostic (3.15e-1)" "unprognostic (1.94e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.18e-2)" "unprognostic (8.80e-2)" 47.1 148.1 22.5 40.6 21.1 64.7 28.0 20.9 22.6 28.0 37.3 50.9 58.4 47.9 21.0 30.7 39.0 55.9 65.8 21.1 29.8 37.9 46.5 63.0 34.4 55.2 26.7 34.1 19.0 33.8 21.2 39.1 33.3 41.0 45.6 20.1 20.8 60.6 67.8 12.4 39.4 51.6 22.9 27.8 52.1 37.8 24.6 42.8 30.4 64.0 34.1 141.6 30.1 25.7 228.4 1032.6 118.1 111.3 553.5 308.0 409.8 412.4 259.3 182.7 186.8 110.5 329.4 169.3 187.0 1452.6 682.1 77.7 235.7 158.6 214.1 82.7 101.8 143.1 765.8 468.0 885.7 226.3 149.9 176.9 159.8 403.7 128.1 557.1 634.0 227.9 200.5 77.5 276.8 109.1 233.4 102.7 114.4 453.0 1053.1 227.3 82.1 146.5 211.2 123.1 182.6 110.6 333.3 519.1 325.2 222.6 123.2 131.4 854.5 89.3 183.7 201.3 341.2 84.8 179.9 254.5 186.8 122.5 538.0 109.4 29.9 69.7 23.6 39.0 26.9 21.3 21.6 23.9 39.5 14.5 19.1 16.7 102.6 24.4 48.4 25.2 19.8 27.6 22.5 21.1 20.9 22.6 21.1 29.8 55.2 26.7 33.3 22.9 24.6 25.7 26.0 64.1 67.5 50.3 27.6 104.0 459.7 41.3 40.9 28.1 19.4 16.3 66.2 32.9 79.3 16.5 22.9 26.1 40.4 93.4 41.1 79.6 45.0 100.9 36.8 116.2 20.4 46.3 48.2 80.7 34.3 90.1 69.8 119.6 53.2 35.2 49.2 68.2 42.0 28.6 56.7 18.8 44.7 43.5 100.5 19.1 68.0 62.2 19.6 49.6 51.9 24.8 26.8 29.1 55.3 197.7 40.5 29.3 28.4 557.4 24.6 37.5 105.5 20.9 0.0 43.4 84.0 14.4 33.8 24.3 72.9 51.3 28.5 98.4 33.0 488.0 UACA "FLJ10128, KIAA1561" ENSG00000137831 "Uveal autoantigen with coiled-coil domains and ankyrin repeats" Q9BZF9 15 70654554-70763558 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 142.0" "Cell type enhanced" "Detected in many" "Adipocytes: 293.0;Cardiomyocytes: 175.1;Endothelial cells: 177.4;Microglial cells: 184.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 244.5;BJ hTERT+: 148.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041412, HPA043503, HPA056006" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA041412: AB_10966708, HPA043503: AB_2678517, HPA056006: " "unprognostic (1.58e-1)" "unprognostic (1.05e-1)" "unprognostic (2.56e-2)" "unprognostic (1.54e-1)" "unprognostic (2.79e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (2.80e-1)" "prognostic unfavorable (7.01e-5)" "unprognostic (4.95e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.14e-3)" "unprognostic (1.45e-1)" "unprognostic (2.42e-2)" "prognostic unfavorable (1.03e-4)" 37.7 17.9 10.5 7.8 13.1 1.0 33.0 11.0 12.9 25.1 24.2 14.6 22.2 22.1 21.5 28.9 21.6 32.2 28.0 9.4 11.8 30.8 17.3 30.7 8.0 13.3 12.8 31.2 12.7 12.5 11.5 28.6 13.0 21.6 15.4 11.9 25.3 18.4 142.0 19.4 22.3 16.0 12.1 30.0 15.9 16.1 14.2 4.6 35.6 106.0 6.7 13.2 25.4 14.7 42.7 34.8 15.2 20.2 29.9 127.9 0.1 244.5 148.4 62.7 53.8 58.5 61.5 29.2 65.6 61.4 18.4 48.1 34.4 19.4 78.3 0.1 15.3 16.4 27.9 12.3 38.8 0.4 6.0 60.8 10.7 37.1 28.1 103.3 67.7 6.9 4.1 0.1 78.7 14.0 0.1 2.6 12.7 19.3 18.0 0.0 109.6 0.2 30.3 14.4 4.0 7.6 46.5 7.1 48.9 30.3 13.4 4.9 130.5 3.6 24.8 20.6 39.1 2.3 8.8 0.2 31.4 4.4 27.4 0.1 0.9 0.0 0.0 1.7 0.0 0.5 0.0 0.0 0.8 1.2 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.3 10.5 13.1 11.0 12.9 9.4 11.8 13.3 12.8 13.0 12.1 14.2 14.7 293.0 6.4 6.4 31.6 5.4 11.3 14.6 13.7 10.2 6.3 22.2 33.3 175.1 18.6 19.2 49.7 4.2 1.0 2.1 66.5 3.9 49.0 21.0 75.3 46.3 177.4 9.1 3.0 0.9 48.7 1.9 81.6 33.6 53.0 15.2 34.9 47.5 18.8 9.6 25.2 0.7 33.1 6.1 24.3 8.6 15.2 125.2 15.8 30.2 184.6 9.5 49.4 2.1 6.0 62.0 78.8 35.7 141.1 0.8 21.8 45.3 5.0 61.9 4.2 52.6 53.5 96.2 46.4 35.2 16.4 13.1 1.0 2.9 62.7 24.2 10.9 UBL3 "DKFZP434K151, FLJ32018, HCG-1, PNSC1" ENSG00000122042 "Ubiquitin like 3" O95164 13 29764371-29850617 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 350.5;Late spermatids: 316.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBF TERT88: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053772, HPA058781" Uncertain Approved Centrosome NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Centrosome "HPA053772: AB_2682258, HPA058781: AB_2683818" "unprognostic (2.83e-2)" "unprognostic (5.48e-2)" "unprognostic (3.20e-1)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (2.20e-1)" "unprognostic (3.22e-1)" "unprognostic (3.22e-2)" "unprognostic (3.63e-1)" "unprognostic (2.02e-2)" "unprognostic (1.86e-1)" "unprognostic (1.59e-1)" "prognostic favorable (4.23e-4)" "unprognostic (8.49e-2)" "unprognostic (1.96e-1)" "unprognostic (5.01e-2)" "unprognostic (2.84e-1)" 23.3 20.7 39.6 17.8 49.6 22.2 29.3 58.0 47.1 38.3 25.9 28.6 27.7 42.4 25.6 42.9 27.1 31.5 20.5 38.5 52.3 35.1 41.7 36.9 19.3 51.5 54.8 30.7 55.8 30.0 17.1 22.6 49.0 22.5 27.7 47.2 29.2 22.7 29.7 24.1 29.0 30.7 53.8 25.2 72.8 22.4 47.3 21.5 40.4 35.5 19.0 19.5 23.6 61.3 12.5 7.8 23.9 14.5 33.0 31.7 25.3 101.2 59.2 42.5 34.0 18.6 27.7 10.9 22.3 101.3 19.7 12.2 11.0 15.1 121.0 17.3 13.5 11.5 9.9 15.0 10.4 17.0 14.8 18.8 48.2 22.4 14.3 36.7 15.5 12.9 5.8 7.7 18.1 84.5 12.8 14.3 14.3 29.3 11.1 14.5 30.8 12.5 28.2 14.7 27.8 13.9 14.3 49.0 106.8 50.6 26.4 28.6 13.4 54.7 13.6 30.3 13.8 17.7 7.4 8.2 19.4 14.4 37.0 10.4 11.2 10.0 10.7 11.4 5.0 2.9 13.5 10.5 10.9 4.1 7.6 9.5 11.2 6.9 13.0 5.1 34.7 9.1 39.6 49.6 58.0 47.1 38.5 52.3 51.5 54.8 49.0 53.8 47.3 61.3 60.7 192.3 46.2 58.4 47.0 77.0 99.6 30.6 57.5 166.8 47.3 29.6 35.6 70.1 63.3 36.8 77.2 17.2 55.2 81.8 92.0 36.7 350.5 113.7 66.4 44.0 60.6 8.6 77.2 37.3 87.9 73.0 154.5 103.6 14.5 16.4 35.0 58.0 39.1 95.9 95.1 58.8 42.7 60.0 92.1 316.1 34.8 69.4 97.8 91.8 56.6 174.9 38.1 97.0 214.1 60.9 34.8 33.1 58.3 65.9 45.1 50.8 80.4 67.9 19.7 91.0 49.6 72.5 24.5 55.2 80.0 29.6 56.8 76.5 43.8 104.0 UBL4B FLJ25690 ENSG00000186150 "Ubiquitin like 4B" Q8N7F7 1 110112443-110113947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 43 "testis: 104.9" "Cell type enriched" "Detected in some" 4 "Late spermatids: 6512.1" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 20.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031364 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA031364: AB_10604000" "unprognostic (2.92e-1)" "unprognostic (3.48e-2)" "unprognostic (3.53e-1)" "unprognostic (9.81e-2)" "unprognostic (1.65e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-2)" "unprognostic (3.43e-2)" "unprognostic (6.87e-3)" "unprognostic (4.46e-1)" "unprognostic (2.20e-9)" "unprognostic (3.29e-2)" "unprognostic (7.39e-2)" "unprognostic (1.59e-4)" "unprognostic (3.90e-2)" 0.3 0.0 0.9 0.0 0.8 0.0 0.6 0.4 1.1 0.1 2.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.1 0.5 1.6 0.1 0.0 0.0 1.1 0.0 0.4 0.2 0.0 0.1 0.4 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.0 104.9 2.4 0.0 0.0 0.7 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 20.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.8 0.4 1.1 0.6 1.2 0.5 1.6 0.4 0.3 2.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1490.4 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6512.1 29.2 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 22.2 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.5 0.0 51.6 18.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 UBXN4 "KIAA0242, UBXD2, UBXDC1" ENSG00000144224 "UBX domain protein 4" Q92575 2 135741734-135785056 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 863.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036325 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA036325: AB_10669788" "unprognostic (1.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (1.47e-1)" "unprognostic (1.54e-1)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (2.91e-1)" "unprognostic (5.40e-2)" "unprognostic (2.94e-2)" "unprognostic (2.63e-2)" "unprognostic (1.93e-1)" "unprognostic (1.83e-2)" "unprognostic (4.44e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-2)" "unprognostic (5.14e-3)" 51.9 55.6 33.3 58.4 38.3 65.4 57.4 37.4 38.0 62.3 44.7 57.1 69.8 56.0 71.1 44.4 49.0 57.2 44.3 31.5 33.8 64.2 93.8 47.2 59.5 40.2 36.8 52.6 73.4 83.5 19.6 63.0 40.1 64.6 60.2 85.6 71.8 47.8 55.1 56.0 67.9 43.9 35.9 55.7 64.6 57.7 33.7 76.6 76.1 52.7 59.8 60.5 25.1 47.6 136.2 34.6 85.1 66.2 106.9 107.0 95.5 106.6 106.3 87.0 77.4 65.3 91.8 84.0 149.4 105.1 46.6 98.3 50.7 68.4 103.5 115.5 62.8 80.5 60.7 98.6 99.4 85.2 70.7 81.6 66.6 86.7 85.8 118.2 110.5 66.2 74.4 116.1 95.3 64.1 109.9 61.3 64.3 70.6 70.9 87.9 100.5 146.5 112.2 97.7 77.4 50.2 97.2 64.1 64.4 77.1 68.0 78.2 101.8 78.4 40.1 82.5 58.4 108.7 72.2 76.2 99.0 59.3 75.5 62.9 35.8 59.1 46.5 42.3 42.6 45.9 42.5 42.5 35.8 42.6 41.4 41.0 73.7 48.4 52.2 56.6 52.3 35.9 33.3 38.3 37.4 38.0 31.5 33.8 40.2 36.8 40.1 35.9 33.7 47.6 178.1 208.3 171.4 56.2 177.4 175.1 283.0 318.5 160.5 172.3 164.1 153.3 150.8 134.4 264.1 126.9 223.1 238.2 140.8 168.9 90.1 254.6 863.9 209.3 223.1 151.7 186.6 129.8 85.2 195.8 214.0 197.4 129.5 240.6 176.9 151.5 113.2 225.7 138.8 97.6 78.4 246.9 183.1 88.6 125.2 325.1 172.7 139.9 92.5 60.9 158.8 162.2 122.6 71.9 105.3 190.7 166.7 143.7 300.3 344.1 183.0 156.8 286.7 349.8 105.2 159.3 173.9 446.1 248.4 176.1 183.6 379.4 171.6 271.6 186.0 303.7 UGGT2 "FLJ10873, FLJ11485, HUGT2, MGC117360, MGC150689, MGC87276, UGCGL2" ENSG00000102595 "UDP-glucose glycoprotein glucosyltransferase 2" Q9NYU1 13 95801580-96053482 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 112.0;Excitatory neurons: 215.1;Inhibitory neurons: 169.6;Oligodendrocyte precursor cells: 209.1;Oligodendrocytes: 207.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.9;eosinophil: 2.6;intermediate monocyte: 6.2;myeloid DC: 3.6;non-classical monocyte: 6.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047955 Uncertain "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA047955: AB_2680222" "unprognostic (5.32e-2)" "unprognostic (2.56e-1)" "unprognostic (2.51e-2)" "unprognostic (1.83e-1)" "unprognostic (9.33e-2)" "unprognostic (8.70e-2)" "prognostic unfavorable (9.99e-4)" "prognostic unfavorable (5.47e-4)" "unprognostic (1.55e-1)" "unprognostic (9.21e-2)" "unprognostic (7.75e-3)" "unprognostic (6.27e-2)" "unprognostic (5.65e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (9.61e-2)" "unprognostic (1.61e-2)" 11.8 6.9 5.1 5.1 6.3 3.8 9.3 1.1 9.1 8.2 6.3 6.9 5.4 10.3 16.0 4.0 7.8 6.0 8.7 5.7 4.3 7.5 8.3 6.7 3.0 3.6 2.9 7.8 10.7 7.6 8.8 11.2 3.5 7.4 6.2 7.8 8.0 7.3 4.0 4.8 4.6 10.0 2.8 3.8 7.8 12.0 3.5 1.2 11.4 4.3 2.6 8.2 6.0 8.1 20.3 9.6 19.8 10.2 32.5 34.4 16.0 32.5 25.2 15.6 26.6 14.6 17.2 7.0 11.8 22.0 11.4 12.4 7.0 7.0 22.9 0.2 8.6 9.0 19.1 9.6 19.0 25.4 20.9 20.6 7.4 5.9 18.7 28.8 14.2 0.1 5.8 11.5 22.1 6.0 0.2 10.9 8.4 15.1 5.8 0.1 14.4 10.5 13.6 19.4 4.1 15.3 18.6 18.4 13.2 26.9 16.4 12.1 23.1 15.7 10.2 17.6 17.1 16.1 8.3 8.8 40.9 13.3 21.2 0.4 5.9 2.6 0.1 6.2 0.0 1.2 0.1 0.1 3.6 0.4 0.1 0.1 0.4 1.1 6.0 0.3 0.0 1.9 5.1 6.3 1.1 9.1 5.7 4.3 3.6 2.9 3.5 2.8 3.5 8.1 22.2 16.0 19.9 112.0 3.9 4.0 10.3 10.6 10.2 19.5 11.0 13.1 13.1 7.2 16.3 14.7 31.3 18.3 0.5 5.8 0.0 13.9 44.7 13.2 34.3 17.7 4.8 7.8 215.1 18.9 17.3 32.4 12.2 20.9 18.3 22.4 12.8 8.6 7.5 18.5 169.6 7.1 8.2 7.1 11.9 15.4 22.1 8.5 3.6 76.8 6.8 11.8 0.0 209.1 207.3 18.6 5.2 16.6 9.8 9.9 4.0 5.6 15.1 17.1 32.9 28.2 32.3 38.1 26.3 8.0 3.1 13.8 1.6 19.5 7.8 7.5 UHMK1 "KIS, Kist" ENSG00000152332 "U2AF homology motif kinase 1" Q8TAS1 1 162497251-162529631 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077624 Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA No "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" Vesicles "HPA077624: " "unprognostic (6.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.08e-2)" "unprognostic (8.16e-2)" "unprognostic (9.63e-2)" "unprognostic (1.82e-1)" "unprognostic (7.81e-3)" "unprognostic (9.10e-2)" "unprognostic (3.11e-1)" "unprognostic (3.44e-2)" "unprognostic (9.08e-2)" "unprognostic (8.77e-2)" "unprognostic (4.66e-2)" 26.8 23.3 21.2 23.3 24.6 40.3 19.3 18.1 21.2 15.1 16.6 19.2 19.1 11.7 14.1 13.3 14.4 13.7 11.6 26.0 28.3 31.2 38.1 17.5 30.8 24.9 28.5 11.9 11.0 27.8 7.8 17.1 28.3 16.2 19.6 10.5 13.5 18.5 25.8 11.9 23.4 10.8 19.8 25.4 20.0 12.2 26.1 24.6 19.4 25.9 28.9 18.1 10.5 19.4 61.9 28.4 14.6 35.8 40.7 31.9 32.7 79.7 43.2 63.9 45.7 18.6 37.8 50.2 67.8 60.0 31.2 34.9 28.2 44.1 102.4 69.1 20.4 49.8 34.3 16.9 31.3 73.4 55.5 33.0 45.8 63.2 59.9 44.6 37.4 34.2 44.1 67.7 111.4 26.0 39.3 19.4 19.4 46.1 37.8 24.9 64.9 41.9 42.6 62.8 26.4 24.3 70.5 64.6 52.2 19.9 56.0 81.0 58.5 72.7 41.0 50.8 112.6 69.2 103.5 58.0 60.5 35.3 67.3 3.6 2.0 2.4 4.8 5.3 4.9 3.2 3.5 4.0 2.3 3.6 3.5 4.0 1.3 3.7 6.1 2.6 3.1 2.6 21.2 24.6 18.1 21.2 26.0 28.3 24.9 28.5 28.3 19.8 26.1 19.4 37.6 19.2 41.2 20.9 75.6 29.4 33.7 38.5 34.7 24.4 39.4 20.2 35.1 40.0 53.8 53.3 12.5 26.2 81.0 53.9 56.7 27.6 55.6 35.1 35.7 33.4 33.5 51.6 37.0 23.2 38.1 25.5 43.3 44.4 45.7 23.3 31.1 85.1 30.0 23.5 27.4 34.1 48.8 73.5 47.5 58.4 21.5 60.0 28.4 33.7 58.0 14.6 74.2 20.6 29.5 40.4 33.0 19.5 47.2 59.9 60.8 62.2 50.9 23.0 0.0 29.2 27.8 25.1 29.6 45.2 24.6 22.4 69.4 31.4 39.3 58.3 USP53 KIAA1350 ENSG00000145390 "Ubiquitin specific peptidase 53" Q70EK8 4 119212587-119295517 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 586.8;Microglial cells: 269.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 327.9;SK-MEL-30: 102.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035844, HPA035845" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA035844: AB_10669532, HPA035845: AB_2674817" "unprognostic (9.33e-2)" "unprognostic (1.49e-2)" "prognostic favorable (3.15e-6)" "unprognostic (4.37e-3)" "unprognostic (4.82e-2)" "unprognostic (5.03e-2)" "unprognostic (1.55e-1)" "unprognostic (9.54e-2)" "unprognostic (1.77e-1)" "unprognostic (9.81e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.54e-6)" "prognostic favorable (3.58e-8)" "unprognostic (9.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.58e-1)" "unprognostic (3.70e-2)" 37.8 14.4 5.6 5.7 5.8 0.9 25.3 6.1 6.2 18.5 11.8 16.3 5.7 13.1 13.1 17.0 30.6 10.2 24.0 4.9 7.3 19.9 7.3 29.4 12.4 9.4 8.1 9.4 24.6 8.1 10.3 10.5 7.3 9.2 16.1 3.4 12.7 11.5 33.5 11.7 9.7 10.2 6.5 7.2 15.1 7.8 8.6 5.4 10.5 51.7 8.0 12.7 12.0 5.5 11.4 6.8 2.4 0.0 60.5 60.4 13.6 70.6 327.9 6.2 8.1 7.4 10.4 46.1 2.5 21.1 12.1 5.5 5.5 5.3 16.1 6.1 4.5 3.1 5.2 2.6 47.2 3.9 0.7 20.3 15.0 21.9 31.0 11.7 29.8 3.0 7.3 1.7 8.4 2.5 2.9 5.2 6.7 7.0 3.8 0.9 11.4 9.2 16.4 7.2 3.8 3.0 3.9 27.5 102.4 13.3 7.0 2.7 32.3 2.0 7.0 26.3 6.4 3.3 5.2 7.8 31.4 1.7 7.9 1.3 0.0 0.0 0.4 0.0 0.5 0.7 1.0 0.8 0.1 0.7 1.9 1.0 0.2 0.9 0.0 0.3 0.9 0.3 5.6 5.8 6.1 6.2 4.9 7.3 9.4 8.1 7.3 6.5 8.6 5.5 27.6 35.3 44.5 80.6 18.5 61.8 73.6 21.2 48.3 17.8 74.1 46.6 99.0 32.9 33.9 119.5 29.2 48.4 15.1 207.8 45.0 33.4 5.6 167.2 45.9 35.7 34.6 4.8 32.4 62.7 17.3 86.0 41.8 586.8 70.8 19.8 23.9 30.5 9.3 25.2 32.5 80.4 52.9 21.3 76.4 7.3 19.0 36.5 14.2 269.8 45.6 25.0 12.3 11.6 11.9 110.6 214.5 10.9 18.6 138.6 46.0 20.1 27.3 31.5 6.6 91.8 32.9 18.0 4.0 62.6 42.3 49.8 26.8 14.8 62.6 124.8 USP9Y "AZFA, DFFRY" ENSG00000114374 "Ubiquitin specific peptidase 9 Y-linked" O00507 Y 12537650-12860839 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Excitatory neurons: 89.5;Inhibitory neurons: 69.5" "Cancer enhanced" "Detected in many" "prostate cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 21.5;RT4: 17.4" "Not detected" "Not detected" HPA057687 Uncertain Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057687: " "unprognostic (2.63e-1)" "unprognostic (8.97e-2)" "unprognostic (1.10e-5)" "unprognostic (8.46e-3)" "unprognostic (4.93e-2)" "unprognostic (2.53e-2)" "unprognostic (2.77e-1)" "unprognostic (3.17e-2)" "unprognostic (1.71e-1)" "unprognostic (4.05e-2)" "unprognostic (1.41e-4)" "unprognostic (2.28e-1)" "unprognostic (1.19e-2)" "unprognostic (1.42e-1)" 3.6 5.2 1.3 1.7 1.4 2.6 3.3 2.8 5.2 0.0 2.5 4.5 1.7 0.0 7.2 5.2 0.0 4.6 5.5 1.3 1.4 7.1 3.0 5.2 2.2 1.2 1.1 0.0 6.0 3.5 8.8 2.3 1.3 9.7 4.9 12.9 4.9 7.0 5.2 3.2 4.4 0.0 1.0 5.1 3.9 4.2 1.4 0.0 5.7 9.7 5.6 4.5 0.0 2.4 0.0 4.7 0.0 0.0 0.0 0.0 5.3 14.2 14.6 7.2 8.5 0.0 0.0 7.7 0.0 12.2 0.0 0.0 0.0 0.0 8.6 8.1 0.0 7.3 0.0 9.5 5.8 0.0 0.0 9.7 8.9 0.0 0.0 0.0 0.0 3.0 0.0 0.0 12.2 0.0 9.8 0.0 4.6 0.0 0.0 0.0 3.5 2.1 21.5 17.4 7.2 0.0 0.0 0.0 4.4 12.5 0.0 0.2 10.6 9.5 0.0 0.0 7.0 0.0 9.7 15.1 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.9 0.4 0.7 0.5 0.1 0.7 0.8 0.5 0.0 0.1 0.0 0.6 0.6 0.0 1.3 1.4 2.8 5.2 1.3 1.4 1.2 1.1 1.3 1.0 1.4 2.4 0.0 25.6 23.5 29.4 11.0 11.7 8.5 9.5 18.2 23.6 0.0 0.0 26.5 7.2 12.6 20.2 64.6 6.3 5.3 0.3 1.9 6.9 0.5 0.0 0.0 5.8 0.0 5.9 89.5 0.0 1.7 8.1 6.6 0.0 2.5 0.0 6.1 2.3 3.1 26.9 69.5 1.1 8.2 5.6 9.3 1.1 12.5 3.6 3.6 31.9 3.6 8.8 14.4 28.6 17.4 2.3 0.0 15.4 4.1 13.2 0.7 6.3 19.9 23.1 0.0 5.2 4.4 2.8 2.6 20.6 11.6 3.4 14.7 0.0 1.5 11.9 VCL ENSG00000035403 Vinculin P18206 10 73995193-74121363 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 339.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 568.3;hTERT-RPE1: 547.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002131, CAB002453, HPA063777" Enhanced Enhanced "Focal adhesion sites" NA NA 750000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Focal adhesion sites" "CAB002453: AB_564057, HPA002131: AB_1080570, HPA063777: AB_2685121" "unprognostic (8.49e-2)" "unprognostic (1.61e-2)" "unprognostic (3.14e-1)" "unprognostic (6.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.62e-3)" "unprognostic (2.72e-3)" "unprognostic (2.67e-3)" "unprognostic (3.42e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (1.29e-1)" "unprognostic (3.68e-2)" "unprognostic (4.03e-2)" "unprognostic (4.02e-2)" "unprognostic (1.89e-1)" "unprognostic (1.37e-3)" 85.8 19.1 9.9 52.2 10.6 41.5 45.3 8.4 11.3 73.9 33.4 180.3 35.3 167.6 45.9 92.2 75.9 69.4 132.2 10.5 11.3 37.2 24.1 68.7 18.7 10.3 10.3 45.2 40.3 51.3 13.8 88.6 13.3 131.7 73.1 12.5 31.6 151.9 136.9 37.9 52.7 224.7 9.9 41.9 63.5 41.3 12.1 12.8 39.6 144.1 23.9 135.7 56.3 8.4 147.2 97.0 174.2 123.8 213.2 246.2 95.8 188.5 568.3 126.3 141.9 88.4 124.0 6.5 153.1 331.6 86.3 183.3 115.7 95.0 132.5 12.3 49.6 69.4 92.2 37.2 116.5 14.1 101.8 205.0 25.0 171.5 154.8 547.4 171.0 11.6 50.7 14.3 213.1 25.2 2.0 16.6 82.8 69.9 342.4 24.0 90.9 18.6 180.4 185.8 6.5 25.8 104.7 117.2 53.9 152.8 54.5 21.2 230.9 136.9 57.0 67.0 179.4 2.6 6.0 28.4 160.0 38.9 39.7 15.0 13.6 36.2 14.9 17.1 10.4 5.6 7.1 7.8 20.7 2.3 2.6 5.3 11.2 4.4 19.0 8.0 1.9 28.3 9.9 10.6 8.4 11.3 10.5 11.3 10.3 10.3 13.3 9.9 12.1 8.4 68.0 99.3 39.7 56.5 13.4 114.7 161.4 68.4 30.7 13.4 39.4 58.5 339.5 37.1 79.8 42.3 85.5 51.5 46.7 91.2 3.9 60.8 5.0 98.2 152.6 60.4 38.3 5.9 63.2 61.6 78.6 74.4 66.3 149.1 35.4 45.5 56.7 34.4 23.6 16.8 47.5 44.5 22.4 31.9 51.0 7.5 50.1 77.9 26.6 55.3 44.7 9.7 61.8 18.6 4.6 125.5 48.3 76.8 8.0 100.1 13.7 14.8 37.7 34.5 105.2 49.6 179.9 18.6 13.7 45.6 93.1 39.7 18.3 44.5 48.7 94.8 VCX3B VCX-C ENSG00000205642 "Variable charge X-linked 3B" Q9H321 X 8464830-8466510 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 64 "testis: 32.8" "Group enriched" "Detected in some" 8 "Spermatocytes: 902.7;Spermatogonia: 1055.5" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "U-138 MG: 18.6" "HPA044996, HPA049357" Supported NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA044996: AB_2679174, HPA049357: AB_2680727" "unprognostic (1.60e-1)" "unprognostic (1.25e-1)" "unprognostic (1.67e-1)" "unprognostic (7.51e-2)" "unprognostic (2.07e-1)" "unprognostic (4.19e-3)" "unprognostic (4.41e-2)" "unprognostic (3.06e-2)" "unprognostic (1.99e-1)" "unprognostic (3.58e-2)" 0.1 0.2 0.2 0.0 0.3 0.0 0.2 0.2 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.2 0.3 0.2 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.5 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.1 0.1 32.8 0.3 0.0 0.4 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 18.6 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.4 0.3 0.2 0.3 0.2 0.3 0.2 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.2 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 75.7 0.1 0.1 0.9 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 1.7 0.2 0.0 0.0 0.0 0.0 54.4 8.1 1.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.1 111.7 0.0 0.1 902.7 1055.5 0.0 0.3 0.1 0.0 0.1 0.0 0.0 VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 39.3;Endothelial cells: 22.0;Leydig cells: 13.7;Microglial cells: 36.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 146.5;HBF TERT88: 114.4;hTEC/SVTERT24-B: 116.5;LHCN-M2: 129.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 7.0" "Secreted to blood" NA NA 383000 340000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" 25.0 6.9 2.6 4.2 2.5 0.2 16.7 2.7 2.8 9.7 2.1 4.7 2.4 7.3 1.8 4.0 8.5 6.8 12.7 2.4 2.4 6.7 4.2 16.8 8.0 3.1 2.8 5.9 1.8 2.7 1.5 19.3 2.9 5.1 3.3 1.2 7.4 5.0 3.1 5.1 6.8 6.6 2.6 3.9 3.2 1.4 3.7 1.1 27.7 4.1 3.4 10.3 7.6 2.5 5.9 2.8 1.8 0.0 25.5 25.3 0.0 146.5 87.3 79.2 62.5 0.0 0.7 0.0 0.0 82.7 33.1 4.4 1.3 54.8 114.4 0.1 2.8 0.0 3.8 0.0 13.9 0.0 0.0 27.0 2.5 116.5 80.5 79.3 49.7 0.0 0.0 0.0 129.9 2.1 0.0 0.0 1.3 0.0 47.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 2.3 3.3 0.1 0.7 0.7 0.2 24.2 83.6 9.2 20.8 42.1 0.2 0.0 0.0 34.9 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 2.5 2.7 2.8 2.4 2.4 3.1 2.8 2.9 2.6 3.7 2.5 39.3 3.2 0.0 10.1 0.1 2.4 1.3 3.2 0.0 1.0 3.2 1.7 1.5 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 3.1 8.3 10.9 22.0 0.0 0.0 2.0 0.0 0.0 9.1 0.0 11.0 0.0 8.5 10.0 0.0 0.3 1.7 2.0 0.0 4.1 0.3 2.2 1.2 13.7 0.4 3.6 36.5 0.0 3.4 0.0 1.5 0.6 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.2 0.0 1.9 11.7 0.2 2.0 0.3 2.0 0.0 0.2 1.9 0.0 3.6 VIT ENSG00000205221 Vitrin Q6UXI7 2 36696690-36814792 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.4;tongue: 41.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 68.3;Fibroblasts: 58.8;Granulosa cells: 45.1;Leydig cells: 115.2;Skeletal myocytes: 45.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 10 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "ASC diff: 33.6;ASC TERT1: 65.2;BJ: 32.9;fHDF/TERT166: 112.3;SuSa: 62.2;THP-1: 35.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.34e-4)" "unprognostic (4.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.20e-1)" "unprognostic (7.78e-3)" "unprognostic (8.32e-2)" "unprognostic (1.81e-1)" "unprognostic (3.08e-1)" "unprognostic (3.35e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (3.66e-6)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (3.62e-3)" "unprognostic (1.41e-2)" 35.4 0.9 0.2 0.5 0.5 0.9 15.4 0.8 0.9 6.0 0.4 3.9 0.4 1.0 0.6 8.7 7.9 2.3 18.6 0.3 0.1 0.2 0.0 1.2 2.3 0.1 0.1 28.7 1.0 0.6 3.1 2.2 0.1 7.0 1.5 0.0 11.6 2.3 12.5 12.7 2.7 0.2 0.0 0.1 4.7 3.0 0.3 1.0 8.9 41.1 2.2 15.0 14.6 0.2 0.0 0.0 0.0 0.0 33.6 65.2 0.0 32.9 7.7 10.4 4.3 0.0 0.0 0.0 0.0 112.3 0.1 0.2 6.2 0.0 6.9 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.3 1.6 0.0 0.0 0.0 2.5 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.7 0.0 62.2 0.0 35.6 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 2.5 2.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.5 0.8 0.9 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.2 4.1 0.0 0.0 0.7 0.0 4.2 0.9 0.0 68.3 0.0 0.2 10.0 3.2 0.0 0.0 0.0 0.0 10.6 0.9 0.3 0.0 0.0 1.2 0.4 0.4 1.1 0.0 0.0 1.8 0.0 11.0 58.8 0.0 0.0 0.0 45.1 0.4 0.0 1.1 0.0 0.7 0.4 0.0 0.0 3.5 2.7 115.2 0.5 7.2 20.6 0.0 0.0 4.1 0.5 0.3 0.0 0.1 23.3 0.8 0.1 0.0 0.0 0.0 0.0 6.6 45.2 6.1 1.1 0.6 1.6 3.4 4.2 1.1 0.1 0.3 0.2 WDR1 ENSG00000071127 "WD repeat domain 1" O75083 4 10074339-10116949 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1232.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020804, HPA036434, HPA070293" Approved Supported "Plasma membrane,Cell Junctions" NA NA 63000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cell Junctions" "CAB020804: , HPA036434: AB_2675121, HPA070293: AB_2732152" "unprognostic (1.35e-1)" "unprognostic (6.64e-2)" "unprognostic (5.31e-2)" "unprognostic (1.32e-3)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (2.63e-3)" "unprognostic (6.83e-3)" "unprognostic (1.69e-1)" "unprognostic (9.00e-3)" "unprognostic (2.52e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.73e-5)" "unprognostic (1.11e-1)" "unprognostic (3.56e-1)" "unprognostic (3.46e-2)" "unprognostic (4.83e-3)" 133.7 77.7 60.2 194.5 58.1 150.9 107.8 56.8 65.4 147.1 104.2 200.8 149.1 261.1 91.0 165.1 179.5 117.4 134.2 69.7 69.7 119.4 84.2 142.8 174.6 68.4 69.7 120.5 63.7 89.6 58.4 105.4 68.6 124.5 141.5 93.0 124.9 173.7 94.8 110.4 148.3 214.6 63.1 110.0 131.7 131.9 62.6 188.0 109.8 89.5 149.6 203.0 139.3 68.8 249.5 246.9 213.2 179.4 160.1 265.9 336.9 612.9 561.7 542.9 423.1 296.4 303.3 173.6 193.3 744.4 579.3 158.8 237.3 451.0 582.4 270.7 82.8 494.1 244.6 213.8 377.9 159.4 538.6 256.7 228.4 552.9 276.3 418.7 599.3 301.6 151.6 273.3 540.7 142.8 700.1 229.0 253.4 200.7 250.4 327.8 197.7 146.7 344.9 394.7 72.4 80.5 265.6 141.3 257.3 282.9 120.1 173.9 909.9 415.7 174.6 345.7 548.0 173.4 296.4 225.5 439.7 240.4 522.9 177.4 115.7 213.6 172.3 195.9 134.4 81.6 143.8 173.0 141.4 61.1 145.6 156.9 201.5 129.0 246.9 154.5 214.9 298.4 60.2 58.1 56.8 65.4 69.7 69.7 68.4 69.7 68.6 63.1 62.6 68.8 66.5 35.3 52.9 10.1 77.0 145.3 204.6 103.5 46.7 22.0 65.9 68.7 62.9 52.9 87.4 104.8 41.7 172.5 126.7 347.1 86.1 282.5 500.8 72.2 63.8 103.6 109.2 56.8 4.7 211.3 302.4 68.7 118.3 111.7 82.4 78.7 84.3 71.8 249.2 33.7 8.4 152.6 138.4 159.4 135.8 1232.1 46.9 174.9 80.0 15.0 303.7 82.6 147.2 11.6 9.6 322.8 244.4 92.2 78.3 150.7 169.0 113.1 73.5 28.0 98.6 46.1 168.1 81.6 64.3 74.9 137.0 231.6 132.2 77.2 172.8 193.6 WDR44 "DKFZp686L20145, RAB11BP, RPH11, SYM-4" ENSG00000131725 "WD repeat domain 44" Q5JSH3 X 118346073-118449961 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038084, HPA046719" Approved Supported "Golgi apparatus" NA NA 1800000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "HPA038084: AB_10675626, HPA046719: AB_2679772" "unprognostic (1.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.34e-1)" "unprognostic (2.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (2.40e-1)" "unprognostic (1.04e-1)" "unprognostic (4.56e-1)" "unprognostic (1.52e-1)" "unprognostic (6.09e-2)" "unprognostic (1.91e-1)" "unprognostic (1.88e-2)" "unprognostic (1.46e-1)" "unprognostic (1.08e-1)" "unprognostic (4.98e-2)" "unprognostic (5.52e-2)" 8.4 7.3 6.6 8.2 8.9 6.0 6.3 7.9 7.6 8.0 2.5 6.8 8.3 7.8 6.7 11.3 5.8 11.8 8.3 7.1 6.9 6.0 12.8 7.9 9.4 6.0 6.5 7.6 6.7 10.1 5.2 7.2 6.1 7.5 6.2 8.4 5.6 10.5 9.7 5.1 7.7 10.4 5.7 8.1 8.6 9.8 7.2 10.6 6.9 8.9 9.2 10.0 6.9 10.1 16.4 9.4 10.0 5.8 16.7 13.6 5.5 25.2 17.6 17.9 25.2 6.4 18.4 4.6 14.4 18.1 15.1 12.6 19.7 12.0 20.6 18.6 8.8 18.5 23.3 4.2 11.5 11.7 12.4 8.1 12.6 17.0 11.4 18.2 16.1 8.5 14.8 15.8 17.3 8.0 9.2 6.9 18.1 12.3 15.1 7.2 8.6 7.2 14.6 10.3 4.3 6.7 23.9 8.3 7.9 17.7 7.4 8.3 20.5 13.3 5.1 18.2 14.4 5.9 10.0 6.5 11.2 13.7 9.1 8.0 3.2 7.3 5.4 4.9 5.5 3.6 4.4 5.4 5.1 3.2 5.1 5.6 2.0 7.2 5.5 3.7 7.1 4.0 6.6 8.9 7.9 7.6 7.1 6.9 6.0 6.5 6.1 5.7 7.2 10.1 14.3 22.4 15.0 18.3 11.0 14.8 7.2 6.3 9.1 8.9 7.6 6.3 11.4 10.0 6.2 12.9 10.4 2.3 9.9 9.6 1.9 5.2 0.4 10.9 10.8 12.0 1.2 5.0 35.2 5.3 2.2 11.1 14.3 17.8 8.8 9.8 5.7 16.7 8.6 1.7 41.2 5.2 4.1 13.6 17.7 1.3 7.2 17.2 7.2 40.3 10.3 7.5 11.3 35.2 89.6 11.0 5.8 11.3 12.1 10.2 6.2 4.2 9.1 7.0 26.3 9.3 11.1 17.5 17.6 12.3 9.2 1.2 14.7 5.7 4.6 7.4 WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780610-42797066 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.0;kidney: 37.6;prostate: 11.6" "Cell type enriched" "Detected in some" 4 "Distal tubular cells: 160.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 32.6;K-562: 36.8;TIME: 34.1;WM-115: 23.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" 1.3 0.0 0.7 1.1 0.9 0.0 2.8 0.8 3.3 0.6 0.3 9.8 1.9 0.2 0.7 8.9 0.4 0.0 0.1 1.7 1.1 37.6 0.2 0.1 0.1 1.1 0.7 4.3 0.2 0.0 1.2 0.0 0.7 11.6 11.0 0.6 1.8 1.1 0.0 0.5 3.7 0.4 0.6 0.1 3.4 0.2 1.0 0.0 0.0 0.3 0.1 0.2 0.4 1.0 2.1 1.2 0.6 0.0 0.7 0.2 4.8 11.9 4.8 4.5 1.3 0.7 1.0 0.6 6.8 32.6 1.2 0.0 0.2 0.3 8.6 0.6 1.8 0.1 0.0 4.7 7.4 0.3 0.7 3.9 1.4 6.4 2.1 2.1 0.3 0.4 36.8 1.3 0.0 1.0 0.0 1.1 0.3 2.0 8.2 0.6 1.2 0.0 0.0 0.5 0.0 0.2 0.1 0.2 1.7 4.1 2.4 2.7 34.1 0.3 3.1 0.5 0.4 6.2 5.3 1.2 0.0 2.1 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.8 3.3 1.7 1.1 1.1 0.7 0.7 0.6 1.0 1.0 0.2 0.0 0.6 0.0 0.5 0.0 0.2 0.0 0.6 0.2 7.1 4.1 1.0 1.5 0.6 7.3 0.0 0.0 0.3 8.0 160.4 0.0 0.0 5.1 1.1 0.2 13.1 0.0 0.2 0.2 0.2 0.1 3.1 6.7 4.5 0.1 0.7 0.0 0.0 0.0 0.2 40.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3.2 0.4 0.0 3.6 0.9 1.0 2.9 0.5 0.0 0.2 0.5 0.8 0.8 12.1 0.4 0.0 0.2 0.0 13.1 0.3 WNT5A hWNT5A ENSG00000114251 "Wnt family member 5A" P41221 3 55465715-55490539 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 27.4;salivary gland: 34.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Basal squamous epithelial cells: 34.7;Club cells: 31.3;Endometrial stromal cells: 101.6;Oligodendrocyte precursor cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 227.2;BJ hTERT+: 315.4;HeLa: 242.1;SiHa: 354.2;U-87 MG: 248.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (2.34e-3)" "unprognostic (1.35e-1)" "prognostic favorable (2.94e-5)" "unprognostic (1.37e-1)" "unprognostic (3.45e-3)" "unprognostic (1.14e-1)" "unprognostic (2.16e-2)" "unprognostic (3.91e-2)" "unprognostic (5.89e-2)" "unprognostic (9.58e-2)" "unprognostic (8.34e-3)" "unprognostic (1.10e-1)" "unprognostic (4.81e-3)" "unprognostic (9.70e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-3)" "unprognostic (3.63e-2)" 2.3 0.8 1.9 3.1 1.9 0.1 4.9 1.7 1.8 5.7 0.6 3.1 3.5 27.4 3.1 16.9 6.7 7.2 1.6 2.5 3.2 2.7 2.6 4.9 2.2 3.9 4.3 9.1 4.3 1.0 1.8 10.8 3.0 4.6 3.2 1.2 34.4 8.3 2.0 2.4 3.8 5.9 3.8 4.0 3.5 1.8 3.1 2.4 2.8 1.7 5.1 18.7 12.1 5.4 0.0 0.4 20.8 0.2 15.8 37.7 0.0 227.2 315.4 46.3 80.4 1.3 0.0 6.6 0.6 132.2 19.5 0.2 10.0 0.2 48.2 0.0 6.2 6.4 242.1 0.1 35.1 0.0 0.4 25.0 5.9 139.2 7.6 22.5 0.1 0.2 0.0 109.5 113.3 0.0 0.1 0.1 11.1 0.5 13.6 0.0 14.1 1.0 6.2 7.6 0.0 1.0 354.2 43.1 0.0 18.0 0.1 0.0 0.0 76.1 13.2 70.0 18.2 25.8 0.0 2.4 248.5 0.3 35.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.9 1.7 1.8 2.5 3.2 3.9 4.3 3.0 3.8 3.1 5.4 1.1 51.3 23.2 4.2 0.0 1.5 1.6 1.4 34.7 13.2 12.1 4.4 4.3 0.0 31.3 12.9 0.0 3.0 0.0 0.2 0.0 0.2 15.8 13.3 101.6 4.3 0.0 0.0 3.0 0.2 0.6 19.9 0.0 13.9 2.5 8.5 1.1 2.6 1.3 0.0 9.0 0.3 10.2 2.4 1.3 4.2 19.6 2.6 0.0 5.6 4.2 1.6 0.0 31.2 0.1 0.4 2.5 30.1 0.1 0.9 2.3 1.0 1.9 1.4 0.0 1.6 7.7 0.1 1.1 17.5 1.6 1.5 1.5 6.5 1.6 9.6 WNT5B ENSG00000111186 "Wnt family member 5B" Q9H1J7 12 1529891-1647212 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 32.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 25.6;Microglial cells: 19.7;Muller glia cells: 40.4;Urothelial cells: 16.2" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;eosinophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 231.4;BJ hTERT+: 143.5;BJ hTERT+ SV40 Large T+: 165.4;BJ hTERT+ SV40 Large T+ RasG12V: 136.4;fHDF/TERT166: 162.6;HBF TERT88: 144.1;hTEC/SVTERT24-B: 144.8;U-138 MG: 142.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061991 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA061991: " "unprognostic (7.44e-2)" "unprognostic (5.59e-2)" "unprognostic (8.14e-2)" "unprognostic (3.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (5.53e-3)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (4.08e-2)" "unprognostic (2.16e-2)" "unprognostic (1.49e-3)" "unprognostic (1.90e-1)" "unprognostic (2.93e-2)" "unprognostic (2.77e-1)" "unprognostic (2.71e-2)" 3.0 2.3 3.6 4.1 4.1 0.5 3.0 2.8 3.7 5.5 1.8 24.6 4.3 7.2 5.0 14.9 6.2 2.8 4.0 2.8 5.3 1.9 4.6 3.0 2.6 4.7 3.9 8.2 1.5 9.0 11.2 3.9 4.6 32.4 5.8 5.4 15.7 20.0 1.4 5.3 5.0 5.4 3.9 5.2 6.4 1.8 4.2 3.7 2.0 6.7 3.0 13.9 9.7 3.1 0.3 0.1 1.4 0.2 34.6 61.2 0.0 231.4 143.5 165.4 136.4 8.7 0.9 2.9 0.4 162.6 111.1 3.5 3.3 0.0 144.1 55.0 7.9 12.8 0.0 0.0 8.5 0.2 0.1 51.3 3.3 144.8 41.3 66.6 0.0 0.1 9.5 51.9 39.4 0.1 0.0 0.3 5.7 0.2 0.5 0.0 2.3 4.0 2.0 0.0 1.0 3.2 4.9 0.5 0.2 17.7 0.2 0.9 0.0 142.4 5.9 56.7 119.7 13.9 2.2 0.7 13.9 0.0 1.5 0.0 1.8 1.5 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 3.6 4.1 2.8 3.7 2.8 5.3 4.7 3.9 4.6 3.9 4.2 3.1 0.9 0.0 0.6 7.5 1.5 0.9 11.0 1.9 25.6 1.8 0.7 6.5 2.2 0.0 3.3 0.0 0.0 1.0 0.2 2.4 0.0 1.1 0.2 1.7 10.4 1.4 0.0 0.0 6.9 0.7 1.1 8.0 0.5 2.7 0.0 0.3 0.4 1.7 5.3 0.0 7.9 1.9 2.0 2.1 2.9 0.5 2.1 2.7 3.6 19.7 4.1 40.4 0.0 4.0 5.6 2.8 5.0 2.6 4.5 8.8 1.0 0.2 4.3 2.7 6.6 7.9 4.3 0.7 5.7 7.7 1.3 0.7 0.2 0.0 1.7 16.2 YIPF5 "FinGER5, SMAP-5" ENSG00000145817 "Yip1 domain family member 5" Q969M3 5 144158162-144170714 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 236.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042338, HPA073622" Supported Supported "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Golgi apparatus, Vesicles" Nucleoplasm "HPA042338: AB_2677953, HPA073622: AB_2686618" "prognostic unfavorable (7.83e-5)" "unprognostic (1.13e-3)" "unprognostic (1.95e-2)" "unprognostic (8.35e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.12e-5)" "prognostic unfavorable (3.26e-5)" "unprognostic (2.89e-2)" "unprognostic (1.99e-1)" "unprognostic (3.64e-2)" "unprognostic (1.20e-3)" "unprognostic (4.79e-2)" "unprognostic (8.79e-2)" "unprognostic (1.69e-1)" "unprognostic (1.24e-2)" "unprognostic (5.11e-2)" "unprognostic (6.49e-2)" 22.2 20.4 8.3 17.7 9.8 21.0 24.1 9.8 11.0 24.7 16.3 25.8 30.5 20.2 21.2 28.6 20.3 21.4 18.1 9.5 12.5 25.4 31.7 20.3 18.9 9.7 10.3 20.6 32.0 25.7 17.0 30.2 11.5 18.3 26.0 20.6 26.2 19.2 9.3 17.7 27.3 28.5 10.3 15.5 22.7 20.9 10.3 16.1 22.6 14.5 23.9 24.0 14.3 12.0 43.2 28.2 36.0 28.6 84.4 90.5 32.9 143.6 96.9 63.2 101.5 45.3 44.0 23.5 67.3 156.9 72.5 38.7 34.7 70.5 84.8 32.9 30.2 17.4 44.9 46.7 68.0 39.3 27.7 69.1 64.3 56.8 46.3 108.9 61.0 25.6 18.8 38.5 86.4 22.5 19.4 22.2 23.3 27.5 30.7 20.3 53.4 39.3 39.4 37.7 24.4 30.0 49.7 26.4 66.5 36.2 54.9 25.5 236.7 74.0 35.8 72.5 57.2 34.7 61.8 29.9 70.7 36.9 55.2 48.9 34.5 48.7 47.2 47.4 53.1 37.9 47.1 52.4 41.2 36.4 49.0 46.3 26.0 41.0 44.7 45.0 62.8 40.6 8.3 9.8 9.8 11.0 9.5 12.5 9.7 10.3 11.5 10.3 10.3 12.0 43.5 38.5 27.4 8.5 35.6 29.4 24.5 49.4 26.2 40.6 33.4 29.6 21.8 31.5 35.9 20.2 33.3 56.7 40.5 33.0 31.3 43.7 14.9 31.4 49.8 44.1 14.8 20.0 19.7 68.3 77.1 51.9 33.6 31.2 36.8 34.1 30.4 34.7 36.5 33.7 16.9 50.1 22.4 34.0 24.4 7.3 35.4 28.7 30.2 6.5 38.3 54.9 27.8 13.6 16.2 60.5 35.5 33.8 70.0 23.4 56.0 36.1 50.6 53.8 39.5 31.8 45.4 83.9 56.0 33.4 26.0 67.5 42.0 41.1 27.4 24.5 YWHAH YWHA1 ENSG00000128245 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta" Q04917 22 31944522-31957603 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 501.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025918 Uncertain NA NA 42000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "CAB025918: " "unprognostic (3.77e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-2)" "unprognostic (1.86e-2)" "unprognostic (1.13e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (1.59e-5)" "unprognostic (8.62e-2)" "unprognostic (1.63e-1)" "unprognostic (4.51e-2)" "unprognostic (3.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.40e-1)" "unprognostic (1.59e-1)" "unprognostic (5.60e-2)" "unprognostic (7.00e-2)" "unprognostic (6.81e-2)" 104.9 82.7 244.8 87.2 309.8 86.8 76.6 96.2 501.2 54.6 4.6 106.3 64.8 68.7 92.8 60.4 73.1 82.4 78.1 386.6 217.9 77.6 61.4 112.2 68.3 156.7 109.2 53.0 69.6 29.5 64.4 100.0 145.9 57.8 111.1 114.1 59.4 70.9 68.7 65.0 68.9 131.0 74.1 57.9 109.3 16.2 118.1 70.4 62.0 54.8 82.4 89.9 58.3 229.8 344.5 142.4 180.8 91.8 112.7 107.0 97.0 321.9 172.0 208.1 228.6 157.8 124.2 202.8 76.6 329.4 116.6 169.1 208.7 183.7 271.4 177.0 157.7 118.7 108.2 156.8 108.5 391.4 132.8 84.9 113.0 176.9 135.6 137.3 201.3 76.9 171.5 155.6 249.6 148.5 121.0 189.8 185.2 197.1 150.8 173.7 201.2 115.1 216.5 153.1 323.5 104.4 184.2 134.7 124.7 245.9 78.2 119.3 248.4 206.0 190.1 138.2 216.6 80.7 130.5 257.7 137.3 162.0 170.9 11.9 19.8 22.0 7.6 16.8 11.1 12.4 9.4 10.8 22.9 13.0 3.7 4.9 11.6 25.4 18.4 6.2 19.5 14.0 244.8 309.8 96.2 501.2 386.6 217.9 156.7 109.2 145.9 74.1 118.1 229.8 259.0 51.3 21.7 27.1 106.6 334.1 223.5 27.3 125.2 54.8 123.6 79.0 51.2 125.8 26.5 126.9 22.9 171.7 53.0 242.8 232.8 148.0 3.9 180.0 81.1 211.7 75.4 269.8 132.0 160.6 145.4 118.8 139.1 153.0 40.0 33.4 120.3 72.1 245.6 53.8 62.9 125.4 34.6 155.6 269.8 13.7 61.2 397.6 300.6 66.5 102.1 80.1 44.3 22.1 42.0 203.3 115.7 80.9 120.4 240.7 93.4 125.5 52.5 73.7 157.8 55.8 197.1 23.3 35.5 164.1 340.0 34.8 95.2 25.7 116.1 191.8 ZBTB20 "DKFZp566F123, DPZF, ODA-8S, ZNF288" ENSG00000181722 "Zinc finger and BTB domain containing 20" Q9HC78 3 114314500-115147288 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 66.5" "Cell type enhanced" "Detected in many" "Astrocytes: 1998.0;Microglial cells: 855.4;Oligodendrocyte precursor cells: 1908.5;Oligodendrocytes: 2090.4" "Cancer enhanced" "Detected in some" "stomach cancer: 1.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015551, HPA016815" Approved Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear bodies" "HPA015551: AB_2669217, HPA016815: AB_1858947" "unprognostic (1.79e-1)" "unprognostic (1.50e-2)" "unprognostic (5.51e-2)" "unprognostic (2.33e-3)" "unprognostic (5.72e-3)" "unprognostic (3.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (1.13e-1)" "unprognostic (2.68e-1)" "unprognostic (7.51e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-3)" "unprognostic (6.94e-2)" "unprognostic (1.41e-1)" "unprognostic (7.83e-3)" "unprognostic (1.81e-1)" 4.1 3.9 24.5 1.1 43.8 2.5 3.4 66.5 43.7 3.4 5.7 1.7 0.8 3.6 9.6 1.2 2.4 2.3 3.5 65.9 30.9 5.2 5.4 1.8 1.8 43.8 42.6 6.8 3.4 2.3 1.4 1.0 32.9 5.4 1.4 8.5 3.0 4.9 7.9 2.3 0.8 2.9 29.9 2.5 1.7 15.8 39.4 1.9 5.0 8.9 1.7 1.6 0.7 41.1 1.4 2.7 1.0 2.8 4.2 1.8 0.0 1.3 2.5 0.8 0.6 1.7 0.5 0.4 3.7 3.2 0.8 0.0 4.0 0.6 0.7 0.3 0.1 0.4 1.7 1.3 0.8 0.1 0.0 1.8 0.2 1.4 0.4 2.4 0.8 0.2 0.1 0.6 4.4 0.0 0.1 0.1 0.3 0.0 0.1 0.1 3.4 0.0 2.9 0.0 0.3 0.7 0.5 0.0 0.9 0.1 0.0 0.3 4.8 1.0 3.5 0.2 1.8 0.9 0.0 0.1 1.7 0.2 1.3 9.7 1.5 6.4 6.8 2.3 4.6 20.4 6.4 6.4 1.9 11.3 8.3 6.8 3.5 5.3 4.6 4.9 3.6 3.5 24.5 43.8 66.5 43.7 65.9 30.9 43.8 42.6 32.9 29.9 39.4 41.1 278.1 160.3 122.6 1998.0 115.4 25.7 38.2 11.3 22.2 123.6 103.7 81.8 48.5 108.7 25.2 294.3 60.5 0.2 56.1 10.3 49.0 231.4 450.3 109.8 628.3 106.4 31.8 20.4 72.3 82.9 0.6 174.5 36.7 170.5 80.6 194.5 56.0 106.0 4.3 80.8 462.3 14.5 40.7 20.4 28.5 111.1 105.6 36.0 32.0 855.4 29.3 127.7 36.0 1908.5 2090.4 107.8 10.5 120.7 58.4 28.0 19.2 198.4 36.4 108.6 85.5 301.2 124.6 6.9 8.7 14.2 18.5 0.5 67.4 140.7 17.2 25.0 ZC3H7B "DKFZp434K0920, FLJ13787, KIAA1031, RoXaN" ENSG00000100403 "Zinc finger CCCH-type containing 7B" Q9UGR2 22 41301525-41360147 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001784, HPA076092" Uncertain Supported Cytosol NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "HPA001784: AB_1080637, HPA076092: " "unprognostic (1.71e-1)" "unprognostic (1.68e-1)" "unprognostic (3.49e-2)" "unprognostic (3.53e-2)" "unprognostic (3.35e-2)" "unprognostic (5.66e-2)" "unprognostic (3.73e-2)" "unprognostic (7.92e-2)" "unprognostic (7.12e-2)" "unprognostic (7.73e-2)" "unprognostic (1.39e-2)" "unprognostic (3.19e-1)" "prognostic favorable (5.43e-7)" "unprognostic (1.43e-2)" "unprognostic (2.92e-2)" "unprognostic (4.81e-2)" "unprognostic (2.89e-1)" 29.5 42.9 37.5 20.2 37.1 16.0 22.9 31.9 43.4 25.6 15.1 25.8 24.3 31.1 13.5 20.3 27.2 17.2 26.1 34.1 38.7 31.4 42.1 26.9 21.4 56.0 35.7 41.3 30.9 44.5 30.5 18.5 58.8 26.0 13.2 17.9 44.9 26.7 24.9 20.0 25.9 20.7 30.2 25.6 24.8 11.6 37.2 25.2 45.9 19.1 15.2 23.5 19.7 36.0 59.0 32.2 42.0 25.6 37.6 33.9 49.1 65.8 69.6 53.8 42.1 35.3 23.8 33.1 79.1 92.0 30.1 39.1 35.7 61.8 27.4 76.0 58.9 29.6 40.2 45.4 50.4 57.4 24.9 42.7 34.6 46.3 56.4 45.7 58.9 25.7 60.4 17.9 46.0 59.1 45.4 29.7 30.3 44.2 24.1 68.7 26.4 37.8 45.9 41.5 27.1 20.3 60.5 36.6 31.5 29.0 24.1 38.1 119.0 52.5 54.4 16.3 40.8 30.8 18.4 33.2 44.0 28.0 46.1 0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.1 0.0 0.3 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.0 37.5 37.1 31.9 43.4 34.1 38.7 56.0 35.7 58.8 30.2 37.2 36.0 15.4 12.8 22.2 14.4 13.1 7.1 12.7 13.4 10.2 22.4 18.2 15.6 10.1 20.0 15.7 22.0 18.8 9.0 11.3 13.5 7.9 14.0 0.9 14.2 25.8 17.9 33.6 7.8 20.1 13.3 9.0 16.4 11.2 16.9 8.2 59.0 19.2 44.0 12.0 42.1 20.6 14.6 26.4 12.9 9.8 3.1 33.2 8.2 12.4 13.1 15.2 9.8 20.6 19.1 17.6 18.8 8.1 29.0 7.4 21.2 23.0 18.5 11.7 22.2 19.7 23.1 18.0 2.0 4.9 8.9 5.8 6.2 11.1 46.9 17.1 14.8 ZFY ZNF911 ENSG00000067646 "Zinc finger protein Y-linked" P08048 Y 2935281-2982506 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 35.7;Late spermatids: 88.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001748, HPA071863" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" Nucleoplasm Nucleoli "HPA001748: AB_1080650, HPA071863: AB_2686463" "unprognostic (1.07e-1)" "unprognostic (7.43e-2)" "prognostic favorable (3.58e-5)" "unprognostic (1.07e-1)" "unprognostic (7.52e-2)" "unprognostic (2.75e-2)" "unprognostic (2.94e-2)" "unprognostic (1.04e-1)" "unprognostic (8.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.91e-1)" "unprognostic (2.54e-2)" 2.6 1.7 0.6 2.5 0.8 8.0 2.1 3.3 2.1 0.0 1.0 2.3 2.7 0.0 3.0 4.6 0.0 3.1 1.9 0.6 1.0 1.7 4.4 1.7 1.3 0.8 0.9 0.0 2.6 1.9 1.6 3.8 0.9 5.0 5.0 2.3 2.7 4.0 3.4 1.8 4.2 0.0 0.7 2.2 2.5 7.2 0.6 0.0 2.8 7.4 3.7 3.2 0.0 1.2 0.0 5.9 0.0 0.0 0.0 0.0 9.3 13.6 13.5 11.5 10.7 0.0 0.0 10.0 0.0 14.6 0.0 0.0 0.0 0.0 14.7 15.5 0.0 19.2 0.2 7.6 9.6 0.0 0.0 10.6 9.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 12.8 0.0 8.5 0.0 4.9 0.0 0.0 0.0 8.1 5.2 7.6 17.7 9.8 0.0 0.0 0.0 13.4 6.4 0.0 6.5 11.7 11.3 0.0 0.1 7.3 6.7 0.0 17.5 1.8 0.0 0.0 0.0 2.7 2.2 2.3 1.8 3.1 2.0 2.5 1.3 2.8 2.4 2.7 1.4 1.5 2.9 1.5 2.0 1.6 1.8 0.6 0.8 3.3 2.1 0.6 1.0 0.8 0.9 0.9 0.7 0.6 1.2 0.0 9.6 10.5 7.2 14.7 11.1 10.6 6.8 10.2 12.4 0.0 0.0 7.6 7.2 10.3 1.8 8.4 5.0 8.0 1.0 0.0 4.4 35.7 0.0 0.0 5.8 1.8 11.1 14.1 0.0 2.8 7.8 11.7 0.0 7.0 0.0 10.0 3.7 3.4 13.5 11.3 1.9 2.0 11.3 12.6 88.9 9.9 10.5 3.6 6.5 8.0 12.1 18.6 7.5 6.7 1.3 0.0 10.9 12.2 11.7 1.9 3.3 7.5 8.6 13.1 6.5 5.9 20.3 7.7 12.8 9.5 3.7 12.7 0.1 2.4 12.0 ZHX3 "KIAA0395, TIX1" ENSG00000174306 "Zinc fingers and homeoboxes 3" Q9H4I2 20 41178448-41317672 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 370.5;Early spermatids: 106.3;Excitatory neurons: 99.0;Inhibitory neurons: 96.5;Oligodendrocyte precursor cells: 139.7;Oligodendrocytes: 142.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046498 Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA046498: AB_2679676" "unprognostic (6.26e-2)" "unprognostic (1.41e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.40e-2)" "unprognostic (4.50e-2)" "unprognostic (2.29e-1)" "unprognostic (3.88e-1)" "unprognostic (3.42e-1)" "unprognostic (7.25e-3)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.53e-5)" "unprognostic (3.06e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (7.52e-4)" "prognostic unfavorable (1.84e-5)" 14.4 15.4 33.8 6.5 32.8 3.4 13.3 31.6 27.4 11.6 16.4 19.8 8.6 15.8 5.7 13.6 15.7 8.4 12.2 30.2 27.7 26.4 17.2 11.6 4.5 37.6 32.1 16.3 11.9 15.4 7.8 4.9 29.9 10.6 8.0 10.8 5.7 11.9 28.5 11.0 11.4 12.1 29.4 4.3 15.5 35.0 36.0 7.0 19.0 20.1 4.8 18.1 11.0 28.6 22.5 6.3 6.6 14.2 52.6 56.3 7.6 31.0 35.4 28.3 19.1 11.4 2.9 15.6 14.7 58.5 7.6 7.0 7.9 39.2 30.0 4.3 7.1 6.6 8.6 8.8 21.6 7.6 7.9 34.6 18.7 21.3 27.3 19.2 12.3 11.7 6.2 10.6 38.3 45.0 11.9 4.5 2.9 10.4 23.0 5.8 18.6 6.2 38.6 6.7 23.0 8.3 20.7 12.0 7.4 5.7 11.6 10.5 19.9 70.2 10.8 25.0 15.5 12.2 8.0 6.9 28.9 11.0 11.4 0.1 0.1 0.4 0.2 0.1 0.4 0.6 0.2 0.1 0.2 0.6 0.4 0.3 0.1 0.6 0.2 0.1 0.2 0.1 33.8 32.8 31.6 27.4 30.2 27.7 37.6 32.1 29.9 29.4 36.0 28.6 29.8 19.2 16.4 370.5 4.7 2.9 3.9 2.6 2.8 19.5 6.3 4.7 12.7 17.2 5.8 22.0 4.2 0.6 3.8 5.5 11.7 3.7 106.3 12.3 33.2 15.1 14.9 3.8 99.0 2.7 2.7 20.5 6.6 26.3 1.3 3.7 16.4 31.6 3.0 40.4 96.5 5.6 4.1 3.5 1.7 32.3 18.6 3.5 1.8 52.5 1.9 28.6 1.0 139.7 142.4 4.6 1.3 24.5 2.7 2.6 12.6 27.0 3.2 7.1 26.3 41.2 10.9 11.0 5.2 6.3 3.7 0.4 2.7 19.7 4.7 2.3 ZNF148 "BERF-1, BFCOL1, HT-BETA, pHZ-52, ZBP-89, ZFP148" ENSG00000163848 "Zinc finger protein 148" Q9UQR1 3 125225669-125375325 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001656, CAB017486" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Golgi apparatus" "CAB017486: AB_794260, HPA001656: AB_1079995" "unprognostic (2.40e-1)" "unprognostic (1.12e-2)" "unprognostic (5.03e-2)" "unprognostic (3.94e-2)" "unprognostic (5.94e-3)" "unprognostic (5.66e-2)" "unprognostic (1.24e-2)" "unprognostic (2.36e-1)" "unprognostic (1.69e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (2.88e-4)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (3.63e-2)" "unprognostic (2.72e-1)" 8.9 7.5 5.6 9.4 8.9 7.9 12.1 12.9 7.8 12.6 0.0 10.8 7.6 13.9 10.2 10.3 12.4 9.5 15.5 4.5 16.4 12.9 11.7 10.3 12.3 4.2 6.5 17.4 9.5 15.8 4.7 9.7 4.2 11.1 11.5 13.1 10.0 11.1 11.1 5.8 8.9 13.7 2.3 11.9 9.8 10.5 14.5 16.9 30.0 12.0 14.4 10.6 6.1 8.3 30.6 19.8 21.1 18.9 18.4 19.7 16.0 27.2 31.5 29.9 28.4 19.1 16.6 24.4 18.5 40.3 24.1 24.4 23.2 20.5 42.4 10.9 8.9 30.1 23.3 9.8 13.6 20.9 29.1 16.1 21.0 28.0 29.4 19.7 20.7 17.7 15.0 20.2 22.3 23.9 26.1 7.7 13.6 20.6 16.8 18.6 23.2 13.9 17.1 33.6 18.2 15.3 36.2 18.2 29.7 11.7 22.7 20.8 26.6 22.6 24.1 28.5 17.5 17.4 21.5 36.6 16.9 13.1 21.3 4.4 15.3 32.0 21.8 14.5 22.5 24.5 19.2 20.9 13.0 22.2 27.9 22.0 51.4 33.2 23.4 11.3 19.6 20.1 5.6 8.9 12.9 7.8 4.5 16.4 4.2 6.5 4.2 2.3 14.5 8.3 54.7 93.0 41.3 92.7 56.7 35.6 26.0 36.2 48.9 68.0 37.0 35.7 75.2 24.3 43.0 33.1 39.6 28.7 53.7 34.7 25.4 37.5 82.0 28.8 54.3 51.6 47.9 32.0 166.7 37.4 24.3 44.5 31.1 38.1 50.6 75.7 37.9 41.0 31.1 75.7 170.3 34.4 26.4 37.1 21.2 135.2 48.1 41.2 17.8 143.4 50.1 45.7 59.8 154.3 151.4 33.7 25.6 59.0 35.8 36.6 28.2 43.9 27.5 39.4 32.9 63.4 60.7 24.4 24.2 32.5 38.4 31.6 52.0 42.0 33.6 35.6 ZNF23 "KOX16, Zfp612, ZNF359, ZNF612" ENSG00000167377 "Zinc finger protein 23" P17027 16 71447597-71463095 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 15.0;Excitatory neurons: 10.0;Inhibitory neurons: 11.2;Oligodendrocyte precursor cells: 13.0;Oligodendrocytes: 16.0;Respiratory ciliated cells: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023534 Uncertain Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "HPA023534: AB_1859140" "unprognostic (8.49e-2)" "unprognostic (1.46e-2)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (3.98e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (9.89e-3)" "unprognostic (2.12e-1)" "unprognostic (8.37e-3)" "unprognostic (2.19e-2)" "unprognostic (2.62e-3)" "unprognostic (3.65e-1)" "unprognostic (6.94e-2)" "unprognostic (9.59e-2)" "unprognostic (6.04e-2)" 5.5 4.3 8.6 5.3 8.4 4.4 6.2 8.8 9.9 5.8 8.9 5.6 2.8 6.9 8.0 4.2 7.1 3.6 5.1 8.6 8.5 5.6 5.4 5.4 6.2 8.4 8.3 8.2 4.6 5.4 14.3 4.7 8.1 5.3 5.7 16.9 4.3 5.8 6.5 5.8 5.0 6.9 8.2 5.7 4.1 6.9 8.6 4.9 7.5 7.1 6.0 4.2 3.5 9.8 7.8 4.7 12.0 8.8 7.6 6.6 7.8 17.1 15.9 11.7 8.6 6.1 7.6 15.1 4.2 13.1 11.4 4.7 7.9 10.2 13.7 4.0 5.2 6.7 5.0 6.5 9.2 12.3 5.7 10.7 9.0 12.1 18.6 10.9 4.1 7.9 11.1 2.9 12.5 13.0 6.4 6.0 13.4 4.0 3.9 3.3 5.3 4.6 7.7 6.4 9.9 12.8 5.5 3.9 5.3 7.5 5.1 6.4 11.5 21.2 7.2 5.9 10.7 6.5 10.6 19.8 16.0 6.2 13.2 0.8 0.8 0.5 1.9 1.8 1.8 1.3 1.0 2.1 1.1 2.7 2.1 1.5 0.0 2.6 1.0 1.9 1.9 0.9 8.6 8.4 8.8 9.9 8.6 8.5 8.4 8.3 8.1 8.2 8.6 9.8 0.6 6.4 2.3 15.0 2.6 0.3 0.3 0.2 2.8 2.6 0.7 0.6 0.4 0.0 3.2 0.0 6.2 0.2 0.4 0.5 1.9 2.0 0.2 1.0 1.0 1.1 0.0 7.8 10.0 1.0 0.3 0.9 1.5 0.5 2.5 1.3 1.1 0.5 0.4 3.3 11.2 1.0 0.0 0.3 0.3 0.0 0.6 0.5 0.0 6.5 0.4 1.4 2.1 13.0 16.0 1.5 1.4 0.0 1.5 0.3 0.7 0.3 9.2 3.3 0.0 0.7 0.9 1.5 1.4 2.3 0.0 0.0 1.4 0.5 1.5 0.1 ZNF883 ENSG00000285447 "Zinc finger protein 883" P0CG24 9 112997120-113050043 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 1.3;retina: 1.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 38.2;Distal tubular cells: 21.5;Inhibitory neurons: 25.0;Oligodendrocyte precursor cells: 35.2;Rod photoreceptor cells: 40.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "fHDF/TERT166: 1.0" "Low region specificity" "Detected in all" NA NA "Cluster 10: BJ & FHDF - ECM organization" "Cluster 56: Bipolar cells - Visual perception" 0.1 0.0 0.4 0.0 0.4 0.1 0.0 0.4 0.8 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.6 0.8 0.1 0.1 0.0 0.0 0.6 0.1 0.0 1.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.8 0.2 0.2 0.6 0.8 0.6 0.1 0.4 1.3 1.0 0.0 0.0 19.9 0.7 0.4 0.6 1.2 4.0 38.2 6.0 8.4 9.9 0.0 0.7 3.7 16.7 0.0 0.6 0.0 21.5 8.7 2.0 0.5 5.5 1.3 1.2 1.3 16.7 0.2 0.0 1.6 4.6 0.9 0.0 7.9 3.6 0.0 0.0 16.8 25.0 0.4 0.0 0.6 0.6 2.4 0.3 0.6 0.0 1.9 0.5 14.6 2.1 35.2 17.1 0.1 0.1 4.9 0.0 0.6 0.0 3.7 0.3 40.5 0.0 1.5 2.6 4.2 10.2 8.9 0.6 0.0 0.7 11.8 0.8 1.1 ZP4 ZPB ENSG00000116996 "Zona pellucida glycoprotein 4" Q12836 1 237877864-237890922 "Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "BJ hTERT+: 3.2" "Not detected" "Not detected" HPA008547 Supported "Secreted in female reproductive system" NA NA "Cluster 10: BJ & FHDF - ECM organization" "HPA008547: AB_1080766" "unprognostic (7.12e-2)" "unprognostic (2.70e-1)" "unprognostic (4.59e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0