Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCD2 "ALDL1, ALDR, ALDRP" ENSG00000173208 "ATP binding cassette subfamily D member 2" Q9UBJ2 12 39550033-39619803 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.7;brain: 8.9" "Cell type enhanced" "Detected in some" "Astrocytes: 71.5;Bipolar cells: 57.2;Excitatory neurons: 33.2;Inhibitory neurons: 34.2" "Cancer enriched" "Detected in single" 7 "glioma: 1.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in single" 4 "T-cells: 4.2" "Group enriched" "Detected in some" 6 "ASC diff: 11.6;HDLM-2: 16.9;Karpas-707: 29.0;SH-SY5Y: 17.3;U-266/70: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.26e-3)" "unprognostic (4.06e-4)" "unprognostic (9.27e-2)" "unprognostic (1.15e-2)" "unprognostic (2.06e-1)" "unprognostic (7.31e-5)" "unprognostic (3.42e-2)" "unprognostic (2.90e-2)" "unprognostic (8.06e-3)" "unprognostic (3.43e-2)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-4)" "unprognostic (5.04e-2)" "unprognostic (8.04e-2)" "unprognostic (1.13e-1)" "unprognostic (6.74e-2)" 15.7 1.7 1.5 1.7 2.2 0.2 2.8 8.9 5.2 5.3 0.0 0.7 0.5 2.7 0.2 0.4 2.7 0.5 4.2 2.1 2.1 0.5 0.1 0.5 2.8 2.2 3.3 0.1 0.1 0.0 0.5 0.0 2.4 0.4 0.7 5.9 2.6 0.6 0.1 0.1 0.7 2.6 1.3 1.6 0.7 0.2 3.6 1.4 0.2 0.3 1.6 0.9 0.6 1.4 0.0 0.0 0.1 0.0 11.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 16.9 0.0 0.1 0.0 0.0 0.6 0.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 9.8 1.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 1.2 0.5 2.8 3.7 0.1 0.3 3.2 4.2 0.1 0.9 0.0 0.6 3.6 1.2 1.5 2.2 8.9 5.2 2.1 2.1 2.2 3.3 2.4 1.3 3.6 1.4 0.4 0.0 0.0 71.5 2.6 0.0 0.0 0.0 0.0 57.2 0.3 0.3 10.9 0.0 0.0 0.0 6.2 0.0 3.8 0.1 0.0 0.0 0.3 0.2 0.5 0.2 0.0 0.0 33.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.1 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.5 1.1 2.2 0.0 13.0 1.3 0.0 0.0 0.7 5.9 0.0 0.0 0.9 2.4 2.3 0.0 0.4 2.5 0.2 0.1 0.0 0.0 0.0 7.8 0.6 0.1 0.0 ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12, lysophospholipase" Q8N2K0 20 25294742-25390835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease variant, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 315.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA026866: AB_1844446" "prognostic unfavorable (3.81e-5)" "prognostic favorable (1.30e-5)" "unprognostic (1.32e-1)" "unprognostic (8.74e-2)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (7.18e-4)" "unprognostic (8.51e-2)" "unprognostic (7.91e-3)" "unprognostic (2.08e-1)" "unprognostic (4.08e-2)" "unprognostic (8.46e-2)" "unprognostic (1.36e-3)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.11e-3)" 29.5 33.0 55.7 27.4 67.3 26.5 26.9 70.0 64.7 32.1 35.9 37.0 47.0 25.3 133.1 50.0 24.8 33.4 30.5 77.3 58.2 45.5 29.8 32.6 30.8 70.9 64.6 30.6 117.8 55.3 42.1 29.6 73.3 35.5 36.4 30.8 36.9 39.9 13.3 52.4 52.8 23.6 66.0 22.0 55.0 19.2 71.8 23.4 80.8 14.8 41.5 37.2 35.1 96.9 67.2 148.3 41.6 50.9 79.6 47.1 93.3 97.0 84.5 73.7 84.6 90.1 93.0 21.8 53.3 77.0 155.1 116.5 44.4 56.8 62.8 22.7 41.9 33.3 46.8 128.4 59.3 33.3 71.6 58.7 42.0 85.4 44.1 95.7 33.2 37.8 25.8 315.3 72.8 142.5 51.8 31.0 29.4 77.8 96.8 39.2 95.3 195.0 43.4 145.7 46.6 39.7 75.4 198.9 133.8 72.3 67.4 47.6 44.6 98.3 63.0 57.1 54.0 38.8 36.1 33.4 61.8 38.7 57.3 15.8 18.8 17.3 9.9 17.0 7.5 3.8 10.2 13.7 17.9 5.1 8.9 8.9 3.6 15.4 17.7 17.0 10.4 8.6 55.7 67.3 70.0 64.7 77.3 58.2 70.9 64.6 73.3 66.0 71.8 96.9 20.7 6.4 6.5 19.2 13.8 17.7 32.0 9.8 19.4 34.5 19.6 19.7 16.6 30.0 13.7 27.6 10.4 91.6 22.2 97.0 27.4 33.7 53.0 24.9 18.1 17.5 34.0 14.5 37.7 34.3 95.2 22.9 35.2 28.3 10.2 26.9 15.0 19.5 114.1 42.1 46.0 28.9 20.3 37.8 43.8 107.1 16.1 62.4 33.8 42.2 58.7 44.1 23.7 50.8 67.5 22.9 77.7 20.7 39.3 31.6 126.7 24.6 13.1 23.3 26.3 13.8 19.5 19.9 37.7 27.2 18.3 130.8 18.0 19.6 33.3 35.2 AC004997.1 ENSG00000248751 "Novel protein" 22 30285238-30299482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 1.3;Karpas-707: 1.0;LHCN-M2: 1.0" HPA073183 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "HPA073183: " "unprognostic (2.09e-1)" "unprognostic (1.68e-2)" "unprognostic (1.01e-2)" "unprognostic (2.64e-2)" "unprognostic (3.83e-2)" "unprognostic (7.25e-3)" "unprognostic (1.17e-1)" "unprognostic (1.30e-3)" "unprognostic (1.18e-2)" "unprognostic (2.46e-1)" "unprognostic (9.84e-2)" "unprognostic (1.92e-1)" "unprognostic (1.83e-5)" "unprognostic (7.90e-2)" "unprognostic (7.28e-2)" "unprognostic (4.96e-3)" "unprognostic (1.02e-2)" 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.3 0.2 0.1 0.3 0.1 0.1 0.0 0.3 0.1 0.2 0.0 0.1 0.3 0.2 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.3 0.0 0.2 0.0 0.1 0.3 0.0 0.3 0.4 0.3 0.2 0.0 0.1 0.0 0.2 0.0 0.7 0.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 1.0 0.0 0.4 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.3 0.0 0.0 0.4 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.2 0.4 0.5 0.4 0.1 0.2 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.6 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC005726.1 ENSG00000258472 "Novel protein" 17 28455752-28614185 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 13.2;Club cells: 5.6;granulocytes: 6.3;Proximal tubular cells: 20.4;Respiratory ciliated cells: 5.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.0" HPA046590 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" Nucleoplasm "HPA046590: AB_2679710" "unprognostic (1.26e-2)" "unprognostic (1.82e-1)" "unprognostic (6.04e-3)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (7.25e-2)" "unprognostic (5.96e-2)" "unprognostic (4.58e-2)" "unprognostic (9.22e-3)" "unprognostic (3.17e-3)" "unprognostic (1.49e-4)" "unprognostic (1.25e-1)" "unprognostic (2.65e-1)" "unprognostic (7.50e-2)" "unprognostic (3.79e-4)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 9.6 13.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.3 2.4 0.0 0.0 5.6 3.7 0.0 1.7 0.5 0.0 1.9 1.2 0.0 1.7 2.4 1.4 0.0 0.0 0.0 2.0 0.8 1.6 0.0 3.2 6.3 2.6 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 20.4 5.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.3 1.1 1.2 0.0 0.0 AC005833.1 ENSG00000255639 "Novel protein" 12 4649101-4774184 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.1;tongue: 18.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA012638, HPA042268, HPA073212" Supported Approved Nucleoplasm,Mitochondria No NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Mitochondria" "HPA012638: AB_2294503, HPA042268: AB_2677922, HPA073212: AB_2686581" "unprognostic (9.01e-2)" "unprognostic (1.36e-2)" "unprognostic (5.11e-2)" "unprognostic (2.54e-1)" "unprognostic (3.41e-1)" "unprognostic (1.55e-1)" "unprognostic (1.10e-1)" "unprognostic (1.31e-1)" "unprognostic (6.29e-3)" "unprognostic (2.94e-2)" "unprognostic (3.24e-1)" "unprognostic (4.16e-1)" 2.1 1.3 1.1 3.8 1.4 2.0 2.6 1.3 1.6 1.9 0.9 14.6 14.2 1.2 1.0 2.2 1.7 1.3 7.0 1.2 1.3 6.8 6.4 1.4 1.7 1.3 1.3 1.0 0.5 7.0 1.9 1.4 1.8 23.1 0.7 2.5 2.4 2.2 1.0 14.5 3.2 1.3 1.3 2.6 3.4 1.3 2.9 1.6 18.4 3.4 2.8 1.5 4.4 7.0 5.1 3.4 3.4 3.5 11.8 3.7 5.2 10.4 8.6 13.6 7.6 8.8 1.0 5.7 6.5 6.0 9.3 6.4 11.9 8.9 5.0 10.0 7.4 8.9 7.1 9.6 3.0 5.0 6.0 5.6 10.2 4.0 10.6 5.9 7.0 19.9 7.8 5.0 3.6 3.3 16.5 10.2 2.2 6.5 9.6 6.0 8.6 8.2 2.7 2.3 5.3 9.5 4.6 11.7 1.8 3.0 5.1 4.7 9.5 2.5 8.3 1.3 4.6 10.6 3.5 4.5 4.5 3.6 7.4 2.6 5.2 7.4 5.9 6.0 4.9 5.7 9.6 3.9 4.1 4.0 0.3 5.6 6.9 8.7 6.7 14.7 1.1 1.4 1.3 1.6 1.2 1.3 1.3 1.3 1.4 1.3 1.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC009070.1 ENSG00000286221 "Novel protein" 16 80828736-81006894 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.4" "Low region specificity" "Detected in all" NA NA "Cluster 2: Karpas-707 - Immune response" 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC090517.4 ENSG00000285253 "Zinc finger protein 280D" 15 56652488-56918571 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 1.5;Alveolar cells type 1: 3.2;Alveolar cells type 2: 1.5;Distal tubular cells: 3.9;Endometrial stromal cells: 2.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/84: 6.9" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" 1.6 1.2 1.5 1.2 2.9 1.0 1.5 1.6 2.0 1.9 0.0 1.2 1.1 2.1 1.0 1.1 1.6 1.4 1.7 1.3 2.5 1.6 1.2 1.3 1.1 2.1 2.2 2.4 3.7 1.5 1.5 2.2 1.4 1.3 1.8 4.3 1.4 2.0 0.9 1.3 1.9 1.4 1.4 1.4 2.5 2.2 2.6 2.3 2.3 0.8 1.1 4.6 1.5 4.0 1.3 1.1 2.6 1.7 1.1 1.1 1.4 1.3 0.9 0.9 1.8 0.3 2.1 1.5 1.2 1.3 0.5 1.3 1.0 2.4 0.0 2.2 1.6 0.1 1.0 0.4 2.3 1.7 0.7 1.2 1.3 1.0 2.5 0.4 3.3 6.1 1.7 0.4 1.2 0.3 1.1 1.2 0.5 3.3 0.3 0.5 1.8 0.3 1.9 3.3 2.0 1.2 2.0 2.5 2.7 3.5 1.8 0.4 3.1 1.7 0.4 2.7 6.9 0.2 1.8 2.9 2.5 0.0 1.5 0.7 1.2 1.6 1.8 0.8 1.2 1.1 1.2 0.9 0.5 1.1 0.1 1.2 0.7 0.3 0.7 0.8 1.5 2.9 1.6 2.0 1.3 2.5 2.1 2.2 2.2 1.4 2.2 4.6 1.5 3.2 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.9 0.6 0.0 0.8 2.2 0.4 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 AC093827.5 ENSG00000285458 "Novel protein" 4 86886472-86936178 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 3.1;Distal tubular cells: 5.9;Respiratory ciliated cells: 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 5.1" HPA057434 Uncertain Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Focal adhesion sites" Cytosol "HPA057434: AB_2683438" 1.3 1.2 2.2 0.7 2.5 1.1 1.9 3.6 3.3 1.2 1.3 0.9 1.0 1.1 2.0 1.3 1.0 0.8 2.7 2.6 2.2 1.7 0.7 1.0 0.5 2.0 2.0 1.1 0.9 1.6 0.9 2.1 1.4 1.2 2.0 1.4 0.9 3.4 2.8 1.0 1.0 1.0 0.9 1.3 1.9 2.1 0.6 2.2 3.7 0.4 0.9 3.6 1.6 1.0 0.4 0.7 1.5 1.3 0.6 1.5 1.6 0.5 0.7 0.7 2.6 0.2 1.3 1.0 1.2 1.1 0.7 0.9 0.6 1.2 0.6 1.2 1.3 0.7 0.8 2.1 0.8 0.9 2.3 0.5 1.7 0.8 0.4 0.6 0.9 5.1 0.3 0.5 0.9 0.7 1.0 1.6 0.5 1.6 0.6 1.3 1.5 1.1 0.5 0.8 1.1 1.0 1.3 0.7 2.0 1.3 0.6 1.1 1.5 0.5 0.7 2.3 1.1 2.3 0.9 1.0 0.6 0.3 0.3 0.3 0.3 0.3 0.5 0.3 0.2 0.3 0.3 0.3 0.3 0.6 0.4 0.4 0.2 0.5 0.1 0.1 2.2 2.5 3.6 3.3 2.6 2.2 2.0 2.0 2.1 1.0 2.1 3.6 0.7 12.8 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 5.9 0.4 0.0 1.1 0.6 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.6 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 2.2 8.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 AC105206.4 ENSG00000288677 "Novel protein" 8 22130604-22130708 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 2.4;salivary gland: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 5.1;U-2 OS: 3.4" NA NA "Cluster 2: Karpas-707 - Immune response" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACHE YT ENSG00000087085 "Acetylcholinesterase (Cartwright blood group)" P22303 7 100889994-100896974 "Blood group antigen proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter degradation" "Blood group antigen, Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 98.2;skeletal muscle: 163.2;tongue: 48.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 86.2;Erythroid cells: 37.7;Exocrine glandular cells: 39.7;Horizontal cells: 55.5;Paneth cells: 118.3;Proximal enterocytes: 45.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.9;CACO-2: 13.0;K-562: 13.9;Karpas-707: 19.7;U-2 OS: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027098 Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 990000 "Cluster 80: Striated muscle - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "HPA027098: AB_2672111" "unprognostic (2.23e-1)" "unprognostic (9.44e-2)" "unprognostic (2.71e-2)" "unprognostic (5.80e-3)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.49e-1)" "unprognostic (2.54e-1)" "unprognostic (1.36e-2)" "unprognostic (2.48e-2)" "unprognostic (8.92e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.88e-5)" "unprognostic (2.95e-1)" "unprognostic (2.59e-2)" "unprognostic (9.28e-2)" "unprognostic (8.38e-2)" 1.4 4.7 20.9 2.2 16.8 7.9 2.0 37.1 32.5 5.0 0.0 7.6 4.9 2.6 0.2 2.3 3.2 1.3 12.5 8.0 98.2 8.8 4.1 4.4 3.5 66.1 54.2 4.6 4.3 4.7 8.3 0.7 72.7 8.1 1.8 5.7 7.1 1.6 163.2 1.3 9.1 0.5 26.2 3.5 2.4 3.9 58.1 3.6 2.3 48.0 1.5 1.4 3.7 10.5 0.0 0.2 0.2 0.2 0.3 0.0 7.9 0.3 0.0 0.1 0.2 13.0 0.1 0.0 0.6 0.0 1.2 0.6 2.0 0.1 0.0 4.6 0.5 0.2 0.1 0.2 0.1 0.0 0.4 0.5 0.1 0.1 0.0 0.0 0.0 0.1 13.9 19.7 0.1 4.3 0.0 0.2 1.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.8 1.5 0.1 0.8 0.0 2.9 0.0 0.0 0.2 0.5 6.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.9 16.8 37.1 32.5 8.0 98.2 66.1 54.2 72.7 26.2 58.1 10.5 0.5 0.0 0.0 3.3 0.5 0.8 20.9 0.9 6.2 13.5 2.9 1.1 6.4 5.7 0.4 0.0 0.0 8.2 0.9 86.2 0.0 10.5 0.0 0.5 1.5 2.1 3.5 37.7 4.7 39.7 2.6 3.0 1.5 2.4 0.0 7.4 2.2 0.4 0.8 55.5 9.7 12.0 0.0 0.3 6.6 0.4 0.6 1.7 1.8 1.0 4.6 11.4 0.0 8.5 0.8 20.1 118.3 0.7 1.8 20.4 45.6 1.1 0.1 6.8 0.0 13.5 4.9 4.1 8.0 1.7 1.0 7.1 0.6 1.4 4.6 15.2 ADA2 "ADGF, CECR1, IDGFL" ENSG00000093072 "Adenosine deaminase 2" Q9NZK5 22 17178790-17258235 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 106.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.6;Glandular and luminal cells: 22.0;Hofbauer cells: 57.6;Macrophages: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.7;EFO-21: 21.4;HUVEC TERT2: 24.0;Karpas-707: 44.9;MOLT-4: 38.9;U-266/70: 23.8;U-937: 39.6" "Low region specificity" "Detected in all" HPA007888 Uncertain "Secreted to blood" NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA007888: AB_1078495" "unprognostic (1.03e-3)" "unprognostic (2.00e-3)" "unprognostic (6.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-2)" "unprognostic (7.01e-3)" "unprognostic (4.48e-2)" "unprognostic (3.09e-3)" "unprognostic (3.80e-2)" "prognostic favorable (9.26e-4)" "prognostic favorable (8.91e-4)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (4.86e-3)" "unprognostic (1.96e-2)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" 14.0 11.3 8.3 39.4 9.9 22.8 17.6 10.6 7.9 22.0 20.5 28.3 18.1 19.9 2.7 12.0 51.5 32.1 39.6 7.8 10.9 14.5 21.1 54.9 47.3 16.3 11.4 12.1 13.9 5.4 22.5 15.2 14.7 15.4 34.3 11.0 15.6 17.1 3.4 4.7 26.1 23.4 13.7 106.3 19.6 18.4 12.9 53.7 16.9 4.3 60.7 34.7 6.5 21.1 0.0 0.0 6.4 0.0 0.2 0.8 0.3 2.3 0.1 0.0 0.0 0.0 23.7 6.0 21.4 7.2 0.0 0.5 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.1 4.0 0.3 0.3 11.3 0.1 0.0 0.1 0.1 24.0 9.0 0.1 44.9 0.9 0.0 38.9 1.1 17.8 0.0 0.1 1.2 0.0 6.5 0.0 9.3 10.9 0.1 0.1 0.0 0.0 19.1 0.2 9.7 3.0 0.1 0.2 0.0 0.0 23.8 2.3 1.7 0.0 39.6 0.0 17.5 212.9 11.3 34.6 204.9 26.8 25.8 27.4 34.1 139.1 19.7 31.6 32.4 10.5 44.9 176.1 57.4 17.2 170.7 8.3 9.9 10.6 7.9 7.8 10.9 16.3 11.4 14.7 13.7 12.9 21.1 8.7 0.0 16.8 0.0 7.2 0.0 0.0 0.0 0.0 0.0 5.1 4.2 0.0 0.0 11.2 5.5 0.0 0.4 13.7 0.0 7.9 1.7 0.0 27.6 6.6 2.2 0.0 0.0 0.0 5.2 0.9 2.1 0.0 22.0 5.1 12.6 0.0 0.0 57.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 12.4 0.0 0.0 3.1 15.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.8 8.2 3.1 0.0 0.0 ADAM22 MDC2 ENSG00000008277 "ADAM metallopeptidase domain 22" Q9P0K1 7 87934143-88202889 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 77.2" "Group enriched" "Detected in many" 4 "Excitatory neurons: 286.7;Inhibitory neurons: 304.9;Oligodendrocyte precursor cells: 184.0;Oligodendrocytes: 125.6" "Cancer enhanced" "Detected in many" "glioma: 4.0" "Region enhanced" "Detected in all" "cerebellum: 77.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 81.8;SH-SY5Y: 76.9;U-266/84: 33.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050325, CAB079064" Supported Approved "Cell Junctions" "Intracellular and membrane" NA NA 180000 "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "CAB079064: , HPA050325: AB_2681087" "unprognostic (1.20e-2)" "unprognostic (8.61e-2)" "unprognostic (3.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.89e-2)" "unprognostic (3.09e-1)" "unprognostic (7.84e-3)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-1)" "unprognostic (3.47e-2)" "unprognostic (4.13e-2)" "unprognostic (2.77e-1)" "unprognostic (1.61e-4)" "unprognostic (4.70e-2)" 2.0 9.1 7.2 0.9 9.2 0.9 1.3 77.2 30.6 6.0 0.0 1.5 0.6 4.6 8.5 0.8 2.4 2.5 2.1 12.2 8.9 3.8 0.2 1.2 2.2 14.4 5.6 3.9 1.0 2.1 3.4 0.3 14.7 11.0 1.4 10.3 0.7 5.1 2.5 1.0 1.1 3.5 2.7 2.0 0.6 1.9 13.8 2.5 3.2 1.2 1.1 1.6 2.6 12.3 2.5 0.7 4.8 5.8 1.4 0.3 3.5 0.1 0.5 0.4 0.5 5.1 8.3 7.4 2.0 0.0 3.5 0.2 7.0 0.1 0.1 20.5 9.0 5.6 5.4 1.5 0.1 6.9 0.1 0.7 0.0 0.1 0.3 6.3 0.5 8.1 0.2 81.8 0.2 6.7 8.9 1.4 11.6 0.6 2.6 5.2 18.8 10.7 0.1 4.1 25.9 76.9 4.1 0.1 0.8 3.7 3.5 0.8 0.1 4.8 3.3 0.9 3.6 18.8 33.2 5.9 4.1 14.2 7.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.0 0.0 7.2 9.2 77.2 30.6 12.2 8.9 14.4 5.6 14.7 2.7 13.8 12.3 2.4 0.0 2.0 45.7 1.1 0.5 1.7 0.0 2.8 28.4 0.5 0.6 3.1 0.0 0.6 1.8 22.9 0.4 1.9 0.3 1.9 0.0 7.8 2.2 6.9 1.5 1.2 1.3 286.7 0.0 0.1 4.8 1.1 3.3 0.0 0.7 0.7 0.0 0.1 15.2 304.9 0.6 0.0 0.3 0.6 1.5 2.5 0.2 1.8 18.7 0.0 1.4 2.1 184.0 125.6 0.0 3.1 2.6 0.9 0.4 0.3 1.0 0.8 10.9 0.0 2.9 3.2 0.8 1.9 0.4 0.4 0.0 2.2 3.7 1.3 0.3 ADAMTS20 GON-1 ENSG00000173157 "ADAM metallopeptidase with thrombospondin type 1 motif 20" P59510 12 43353866-43552203 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 3.1" "Group enriched" "Detected in some" 4 "Bipolar cells: 5.1;Inhibitory neurons: 16.1;Oligodendrocyte precursor cells: 11.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "medulla oblongata: 2.8;pons: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 3.6;NB-4: 1.6;NTERA-2: 2.8;SuSa: 2.2;U-266/70: 4.0;U-266/84: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027608, HPA027609" Uncertain "Secreted to extracellular matrix" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA027608: AB_10600098, HPA027609: AB_10599024" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (1.91e-2)" "unprognostic (2.04e-1)" "unprognostic (9.61e-2)" "unprognostic (3.29e-1)" "unprognostic (6.67e-2)" "unprognostic (2.26e-1)" "unprognostic (1.05e-4)" "unprognostic (7.42e-2)" "unprognostic (2.02e-1)" "unprognostic (9.81e-3)" "unprognostic (2.57e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.5 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.1 0.0 0.0 1.6 2.8 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.2 0.7 0.0 0.0 0.0 0.3 0.0 0.0 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 2.8 0.1 3.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ADGRE1 "EMR1, TM7LN3" ENSG00000174837 "Adhesion G protein-coupled receptor E1" Q14246 19 6887566-6940459 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 6.8;lymphoid tissue: 14.8" "Group enriched" "Detected in some" 6 "Kupffer cells: 31.5;Macrophages: 13.2;monocytes: 13.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "basophil: 166.4;eosinophil: 324.9" "Group enriched" "Detected in many" 18 "granulocytes: 324.9;monocytes: 105.0" "Cell line enhanced" "Detected in some" "A549: 7.9;BJ hTERT+: 10.5;GAMG: 10.9;HDLM-2: 26.5;HMC-1: 18.1;Karpas-707: 22.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA052809 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA052809: AB_2681959" "unprognostic (2.06e-2)" "unprognostic (3.45e-1)" "unprognostic (1.32e-1)" "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (6.93e-5)" "unprognostic (6.77e-2)" "unprognostic (1.18e-1)" "unprognostic (5.75e-2)" "unprognostic (1.09e-1)" "unprognostic (2.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.37e-7)" "unprognostic (6.69e-2)" "unprognostic (3.33e-4)" "unprognostic (1.11e-2)" "unprognostic (1.35e-1)" 1.9 0.1 0.3 7.3 0.3 6.8 0.2 0.2 0.7 0.1 0.4 0.9 2.9 0.2 1.1 0.1 0.2 1.0 0.2 0.2 0.7 0.3 2.6 4.6 1.5 1.3 0.9 0.0 0.1 0.2 0.1 1.3 0.7 0.2 0.7 0.0 0.2 0.1 0.1 0.0 2.9 1.9 0.5 14.8 1.0 0.9 0.3 3.4 0.1 0.1 1.5 4.0 0.0 0.9 2.8 7.9 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.2 0.2 0.0 0.0 10.9 0.0 0.0 0.0 0.0 26.5 0.0 0.1 0.0 0.0 0.0 0.6 18.1 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 22.3 0.0 0.2 0.7 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.4 0.3 0.4 0.2 1.1 4.2 0.1 5.1 5.2 0.0 166.4 21.1 324.9 0.1 58.6 0.3 0.1 7.2 0.9 12.0 0.1 8.9 0.6 7.9 0.9 105.0 0.5 2.2 10.0 0.3 0.3 0.2 0.7 0.2 0.7 1.3 0.9 0.7 0.5 0.3 0.9 0.0 3.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.8 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.3 1.8 0.0 0.6 0.0 0.0 31.5 0.0 0.4 0.0 13.2 0.0 0.0 13.2 0.0 1.0 0.5 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 1.3 0.0 0.0 0.1 0.8 0.1 0.0 0.1 ADIPOR2 "ACDCR2, PAQR2" ENSG00000006831 "Adiponectin receptor 2" Q86V24 12 1688574-1788674 "Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 321.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043737 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA043737: AB_10964205" "unprognostic (1.52e-1)" "unprognostic (2.11e-1)" "unprognostic (2.44e-1)" "unprognostic (3.37e-2)" "unprognostic (2.73e-1)" "unprognostic (1.34e-1)" "unprognostic (5.33e-2)" "unprognostic (7.66e-3)" "unprognostic (4.86e-2)" "unprognostic (1.61e-1)" "unprognostic (5.34e-3)" "unprognostic (2.29e-2)" "unprognostic (1.18e-2)" "unprognostic (1.15e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (5.85e-2)" 55.1 72.3 36.6 10.6 49.8 9.6 44.2 46.4 48.7 25.8 28.3 32.2 22.2 24.4 8.1 45.2 23.3 9.7 33.3 35.3 40.6 22.4 79.6 44.6 9.8 50.9 46.9 25.1 31.1 16.9 26.1 13.0 49.5 20.7 17.7 13.1 22.2 11.9 42.9 31.9 32.7 12.0 41.6 19.9 44.7 27.7 44.5 12.8 28.0 19.9 12.6 21.4 29.3 67.0 34.3 28.0 23.1 21.4 21.4 25.6 30.9 24.6 28.4 31.5 44.5 42.1 51.6 24.1 7.8 23.0 56.7 26.1 34.7 35.8 44.9 62.7 28.7 47.3 22.7 30.3 21.2 36.1 29.3 22.6 35.5 39.8 45.6 28.7 23.1 25.8 31.7 50.9 23.7 48.8 23.6 32.8 46.3 28.4 14.8 19.5 43.7 18.3 31.4 19.9 6.9 16.4 22.7 43.8 51.5 39.7 24.6 46.5 23.2 17.8 37.5 28.6 36.2 12.3 16.5 39.5 21.7 32.3 24.7 0.7 0.7 1.8 0.9 0.7 0.7 0.5 0.5 0.8 0.5 0.5 0.6 0.7 0.9 0.6 0.6 0.9 0.7 0.3 36.6 49.8 46.4 48.7 35.3 40.6 50.9 46.9 49.5 41.6 44.5 67.0 81.5 12.8 32.4 39.2 21.8 23.7 25.0 26.6 22.8 11.3 29.9 20.3 22.3 31.5 36.6 14.7 18.8 13.9 32.4 91.4 11.7 22.6 56.3 17.8 15.4 41.1 37.5 38.1 35.7 31.4 42.2 21.1 61.7 30.2 36.3 28.8 28.9 113.4 18.2 18.5 41.3 49.0 32.6 27.3 18.9 77.0 15.8 32.6 26.6 124.6 27.0 32.5 27.8 32.2 321.0 39.6 49.4 22.6 30.2 27.8 41.5 10.8 21.7 16.0 6.6 21.3 25.7 45.0 42.2 29.7 34.4 29.3 26.1 39.6 33.5 29.8 ADPRH ARH1 ENSG00000144843 "ADP-ribosylarginine hydrolase" P54922 3 119579268-119589945 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 14.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 23.9;HEL: 17.1;HMC-1: 18.5;Karpas-707: 25.3;U-266/70: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001701, HPA036961" Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Nuclear membrane" Nucleoplasm "CAB001701: , HPA036961: AB_2675405" "prognostic favorable (2.42e-4)" "unprognostic (2.29e-1)" "unprognostic (4.77e-1)" "unprognostic (2.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.65e-1)" "unprognostic (3.06e-2)" "unprognostic (2.63e-1)" "unprognostic (4.24e-2)" "unprognostic (3.31e-3)" "unprognostic (1.88e-1)" "unprognostic (1.71e-1)" "unprognostic (6.04e-2)" "unprognostic (2.60e-3)" "unprognostic (8.87e-2)" "unprognostic (2.03e-1)" "unprognostic (4.35e-2)" 10.6 6.2 3.0 7.3 3.3 3.4 7.9 3.3 4.2 6.9 9.2 5.5 2.3 6.0 4.9 4.0 4.2 6.9 8.5 2.9 3.5 4.9 3.1 13.5 11.0 4.6 3.4 1.9 6.7 8.0 2.0 11.3 4.4 6.1 4.1 6.6 5.1 9.3 11.8 2.6 5.4 9.2 4.2 11.9 3.9 2.4 4.6 5.9 5.8 9.9 13.0 6.5 3.4 4.9 2.4 3.0 0.7 0.0 2.4 2.7 0.0 2.1 0.4 1.8 2.3 0.9 2.0 0.6 0.9 3.2 0.1 0.2 2.0 0.0 1.7 23.9 0.2 17.1 0.4 0.0 3.9 0.1 18.5 4.0 0.1 0.9 0.1 0.8 7.3 0.0 1.6 25.3 11.0 0.7 0.0 4.1 6.9 0.2 5.8 0.0 8.2 1.1 1.0 0.9 0.5 0.1 0.0 0.1 6.4 1.0 4.4 10.6 6.0 0.0 1.1 4.6 0.4 24.5 5.8 0.1 3.0 0.0 4.6 13.9 18.7 19.1 0.8 17.2 0.8 11.0 1.9 1.7 11.2 6.8 0.2 0.7 0.6 5.3 13.9 9.8 14.3 7.5 3.0 3.3 3.3 4.2 2.9 3.5 4.6 3.4 4.4 4.2 4.6 4.9 12.6 9.6 8.6 0.3 5.0 0.8 0.7 0.4 0.0 0.5 1.5 1.9 4.7 2.8 2.7 3.7 4.2 5.8 5.0 0.3 1.9 3.6 0.7 0.2 0.9 9.9 0.0 2.7 0.1 3.2 3.8 2.1 2.6 0.5 10.8 2.5 7.1 1.6 9.4 0.0 0.2 0.2 2.0 12.2 11.1 0.5 0.3 14.8 1.8 4.7 10.2 0.8 4.1 0.0 0.6 2.1 0.5 3.0 3.9 0.7 0.0 1.3 2.1 4.3 0.0 3.6 3.9 0.4 0.6 0.1 0.9 11.8 1.2 0.7 0.2 0.2 AGA ASRG ENSG00000038002 Aspartylglucosaminidase P20933 4 177430774-177442437 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 77.5;Karpas-707: 111.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031415, HPA031417" Enhanced "Intracellular and membrane" NA NA 36000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA031415: AB_10603578, HPA031417: AB_10670967" "unprognostic (8.76e-2)" "unprognostic (1.56e-1)" "unprognostic (2.22e-3)" "unprognostic (2.11e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (8.61e-4)" "prognostic unfavorable (1.99e-4)" "unprognostic (3.79e-1)" "unprognostic (6.44e-2)" "unprognostic (4.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.09e-1)" "unprognostic (7.49e-2)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (7.42e-2)" "unprognostic (1.47e-2)" 9.4 13.3 8.1 9.1 10.4 15.4 21.1 9.8 12.0 9.2 16.2 13.1 9.6 8.6 30.2 15.9 8.4 13.1 7.5 8.4 9.9 15.3 18.7 11.6 12.2 11.4 9.1 10.2 15.1 17.1 6.1 8.4 11.4 11.8 13.1 6.6 14.9 9.8 9.0 20.6 12.4 9.5 9.5 10.3 16.2 13.2 8.6 11.1 15.8 5.8 15.6 10.9 8.2 13.7 5.4 11.9 13.3 18.8 14.9 13.2 9.0 39.5 77.5 20.1 24.8 6.2 26.2 26.9 7.2 30.0 9.7 6.5 11.3 13.0 39.4 17.3 7.5 11.2 11.9 17.3 10.0 19.6 7.4 9.6 22.5 14.7 6.5 18.0 18.7 11.4 10.3 111.6 8.0 14.6 15.9 12.0 5.2 10.5 12.2 5.0 5.4 4.0 20.5 12.9 7.3 16.4 11.9 10.3 32.2 9.9 23.3 39.8 6.1 13.9 12.3 6.6 15.2 21.2 17.4 14.0 22.3 22.0 16.0 26.4 15.3 23.9 15.6 27.5 17.9 13.9 16.6 18.8 14.8 12.9 14.8 21.3 3.3 12.7 35.8 15.8 17.8 15.1 8.1 10.4 9.8 12.0 8.4 9.9 11.4 9.1 11.4 9.5 8.6 13.7 12.6 12.8 13.5 2.6 20.5 24.0 17.4 26.9 12.5 3.9 19.8 16.9 7.5 15.7 21.7 14.7 2.1 26.3 17.6 8.4 5.9 28.2 13.6 8.9 8.5 10.9 5.4 7.8 3.7 31.3 32.0 16.0 13.7 12.5 14.0 13.9 8.2 23.5 23.1 6.7 2.3 18.2 14.2 15.4 23.3 9.2 11.1 15.9 39.2 2.8 23.8 19.1 11.3 3.5 19.3 21.4 9.1 9.8 48.8 13.4 15.1 22.1 10.5 4.8 0.0 8.4 14.1 35.8 36.6 23.7 27.3 22.7 22.5 14.1 13.6 17.7 AL022318.4 ENSG00000284554 "Novel protein" 22 39014363-39033276 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "lymphoid tissue: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "Karpas-707: 2.7" HPA055116 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "HPA055116: AB_2682701" 0.1 0.2 0.2 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.3 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.2 0.2 0.2 0.3 0.1 1.1 0.3 0.3 0.2 0.2 0.0 0.0 0.0 0.4 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.3 0.0 0.1 2.5 0.4 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 2.5 2.0 1.3 2.8 2.3 3.6 0.1 2.8 1.5 1.5 0.0 0.6 1.8 1.0 2.8 0.0 0.2 0.2 0.2 0.4 0.2 0.2 0.3 0.3 0.4 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL391987.2 ENSG00000204805 9 61861625-61863200 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 17.4;choroid plexus: 11.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "eosinophil: 1.8" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.8" "Cell line enhanced" "Detected in many" "Karpas-707: 16.4" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Karpas-707 - Immune response" 1.4 1.5 14.4 1.1 13.3 0.6 1.6 16.1 14.0 0.8 11.9 1.5 2.6 1.3 0.8 1.2 4.8 1.0 1.3 17.4 13.3 3.2 0.6 0.8 0.9 14.2 12.5 1.6 2.2 3.8 1.7 12.4 2.4 2.0 6.0 1.4 1.3 1.0 2.7 2.3 0.9 11.1 1.8 2.1 8.4 12.7 3.2 1.4 0.5 0.6 0.8 11.0 6.6 1.7 3.7 7.5 2.4 0.7 0.0 1.0 0.6 0.7 1.2 0.3 3.8 1.1 0.1 0.5 3.8 7.4 8.1 3.8 0.8 2.0 7.6 1.3 7.0 5.7 3.2 2.8 4.5 1.9 11.5 0.7 2.5 1.0 2.7 6.6 14.3 16.4 1.4 0.2 4.9 4.0 0.6 7.5 13.6 1.1 1.6 4.9 10.6 0.5 14.8 5.1 2.1 1.6 4.3 0.7 2.3 2.9 2.1 1.0 7.9 2.0 2.3 1.8 0.2 2.4 1.3 4.7 6.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 14.4 13.3 16.1 14.0 17.4 13.3 14.2 12.5 12.4 11.1 12.7 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL592183.1 ENSG00000273748 Unmapped 54224-83311 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 37.4;Ionocytes: 42.7;Langerhans cells: 34.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 103.6" "Low region specificity" "Detected in all" HPA049380 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA049380: AB_2680736" 33.2 24.0 7.9 24.4 13.5 27.7 30.0 17.6 22.3 21.4 8.4 28.3 32.5 55.2 69.3 32.3 22.3 70.8 30.7 9.5 16.5 37.4 21.6 13.2 69.3 9.8 9.5 30.7 24.3 15.1 26.4 12.3 22.6 25.8 49.2 30.2 32.8 20.5 39.0 21.5 20.2 8.8 26.5 29.0 15.3 9.4 18.5 49.1 6.8 42.7 18.9 16.7 60.5 5.9 1.2 33.2 36.7 44.3 7.3 43.9 35.0 23.8 39.4 2.9 44.2 35.5 17.4 11.2 21.1 31.7 8.9 0.9 28.5 73.5 30.9 31.7 10.4 15.5 0.9 47.7 47.9 49.5 5.0 9.2 21.5 60.4 15.2 28.5 64.8 103.6 15.6 2.0 34.3 27.9 4.8 5.0 3.8 46.7 6.6 18.9 31.7 27.8 4.9 45.7 3.4 14.0 5.5 13.6 10.0 30.9 15.5 7.4 3.5 5.5 8.2 56.7 91.6 19.1 42.8 8.7 11.9 9.2 2.5 7.3 3.5 3.0 4.9 8.1 4.7 4.6 2.7 6.8 5.7 5.7 2.4 4.8 5.2 4.2 4.8 3.4 7.9 13.5 17.6 22.3 9.5 16.5 9.8 9.5 12.3 8.8 9.4 16.7 3.0 6.4 9.5 0.0 5.6 14.8 20.0 37.4 0.6 2.5 3.5 8.4 0.0 5.7 16.9 3.7 2.1 2.2 1.7 0.7 7.9 4.0 0.2 2.1 1.9 7.4 1.2 4.8 0.0 1.3 0.7 5.6 0.0 1.2 16.4 1.7 6.4 1.8 2.5 0.0 0.0 3.4 42.7 12.9 34.4 0.5 5.0 4.1 17.8 0.0 2.8 5.0 1.0 0.0 0.0 2.2 1.3 7.2 2.0 4.8 1.5 3.3 18.2 5.2 13.1 7.8 6.7 0.3 1.6 1.1 12.4 1.9 8.2 1.0 3.4 11.9 AL627230.1 ENSG00000275493 9 67725914-67726255 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.4" "Cell line enhanced" "Detected in many" "K-562: 14.5;Karpas-707: 19.6;PC-3: 12.0;SCLC-21H: 17.1" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 2: Karpas-707 - Immune response" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (2.79e-3)" "unprognostic (2.78e-1)" "unprognostic (3.24e-2)" 1.2 0.9 2.9 1.4 2.3 1.3 0.4 9.5 9.3 0.4 1.0 1.1 2.1 1.5 0.0 3.6 2.5 1.9 1.1 10.3 0.3 1.6 0.1 0.8 0.9 0.8 0.3 1.6 4.8 0.2 1.0 0.9 1.1 0.5 1.9 2.2 0.0 0.4 3.7 2.1 0.2 0.2 0.8 1.6 4.1 1.8 0.2 1.3 0.0 0.0 0.9 0.8 2.9 2.3 1.4 5.6 1.6 0.5 0.0 0.8 0.0 0.0 0.9 0.0 2.5 0.7 0.4 0.0 3.9 4.4 6.4 1.6 0.0 1.5 1.1 1.7 10.2 2.4 2.1 0.4 4.2 0.6 6.1 0.0 0.0 1.2 0.6 6.8 14.5 19.6 0.0 0.5 2.9 0.4 0.2 1.8 12.0 0.9 3.8 2.1 2.1 0.3 17.1 4.5 5.0 2.2 1.5 0.5 0.0 0.4 1.7 2.6 6.5 3.7 2.2 0.5 0.1 3.8 1.5 5.8 5.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 2.9 2.3 9.5 9.3 10.3 0.3 0.8 0.3 0.9 0.2 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALG13 "CDG1S, CXorf45, FLJ23018, GLT28D1, MDS031, TDRD13, YGL047W" ENSG00000101901 "ALG13 UDP-N-acetylglucosaminyltransferase subunit" Q9NP73 X 111665811-111760649 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Glycosyltransferase, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002853, HPA005498" Approved Approved Vesicles,Cytosol NA NA 11000000 "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Vesicles Cytosol "HPA002853: AB_1078131, HPA005498: " "unprognostic (4.13e-1)" "unprognostic (1.80e-1)" "unprognostic (2.45e-2)" "unprognostic (1.51e-1)" "unprognostic (6.97e-2)" "unprognostic (6.14e-2)" "unprognostic (2.74e-1)" "unprognostic (6.55e-3)" "unprognostic (2.26e-2)" "unprognostic (3.39e-3)" "unprognostic (1.73e-2)" "unprognostic (4.62e-3)" "prognostic unfavorable (1.10e-6)" "unprognostic (1.19e-1)" "unprognostic (1.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.45e-2)" 15.1 17.9 10.5 18.8 11.7 16.6 18.3 11.5 19.0 17.2 12.3 18.2 13.7 16.1 20.5 14.7 15.4 16.4 13.2 10.2 13.8 21.0 23.8 13.8 23.4 12.6 12.1 15.8 14.7 23.4 17.9 14.1 13.3 17.7 19.4 11.8 15.6 13.4 9.2 19.4 17.3 17.5 11.4 18.5 15.5 17.4 11.8 17.3 18.2 9.9 20.1 21.3 14.7 16.6 22.3 24.4 21.8 13.8 13.8 19.6 12.3 17.7 18.3 22.4 27.5 24.9 23.1 19.5 33.0 24.7 46.5 12.6 26.1 12.5 23.5 14.4 17.6 10.7 26.1 28.4 20.3 19.5 40.5 23.6 22.8 18.0 38.6 23.3 24.8 21.8 23.9 53.5 22.5 55.8 16.4 17.6 19.9 66.3 33.6 12.8 13.9 26.7 36.6 34.0 13.1 19.1 25.2 15.2 16.3 21.7 13.6 18.5 16.7 19.2 9.7 24.9 34.4 25.8 47.1 31.5 20.5 25.5 15.2 39.5 15.8 16.6 9.5 16.3 9.3 10.6 10.6 9.2 18.5 12.1 13.0 10.8 3.0 4.6 12.9 9.5 14.6 9.6 10.5 11.7 11.5 19.0 10.2 13.8 12.6 12.1 13.3 11.4 11.8 16.6 50.9 16.0 30.8 33.6 127.9 35.2 65.8 53.5 33.6 15.1 33.9 31.6 18.7 22.8 36.0 18.4 10.4 27.3 73.9 39.2 45.0 37.4 21.1 48.2 31.1 37.4 26.5 27.1 64.7 52.1 39.1 34.6 37.2 47.9 109.8 15.7 28.2 28.4 42.5 11.8 57.4 49.0 46.8 39.2 52.3 9.4 21.5 56.1 28.4 83.4 41.8 16.0 29.9 41.7 77.5 58.0 55.6 16.1 60.4 46.9 38.5 55.5 35.3 16.5 26.3 38.7 46.2 32.6 22.4 26.5 35.4 48.7 71.1 28.8 32.8 64.6 ANKDD1A FLJ25870 ENSG00000166839 "Ankyrin repeat and death domain containing 1A" Q495B1 15 64911902-64958691 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 209.6;Leydig cells: 61.8;Peritubular cells: 78.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 24.1;RT4: 17.7;U-266/84: 25.4" "Low region specificity" "Detected in some" "Region enhanced" "Detected in all" "cerebellum: 13.8" HPA040757 Approved Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA040757: AB_10960566" "unprognostic (3.72e-4)" "unprognostic (1.86e-1)" "unprognostic (6.07e-3)" "unprognostic (3.25e-2)" "unprognostic (4.78e-1)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-3)" "unprognostic (5.11e-3)" "unprognostic (5.57e-2)" "unprognostic (4.37e-2)" "unprognostic (1.60e-1)" "unprognostic (3.15e-7)" "unprognostic (1.06e-1)" "unprognostic (1.98e-1)" "unprognostic (8.04e-3)" "unprognostic (1.64e-2)" 3.6 9.0 5.1 2.6 4.5 2.7 1.5 2.0 5.4 2.3 0.1 1.3 1.2 2.2 1.9 3.6 4.0 2.9 2.2 3.8 2.5 0.8 0.4 2.6 4.8 4.7 2.7 3.8 4.4 4.4 1.2 1.6 2.2 2.3 0.4 2.8 2.4 2.1 1.2 3.3 1.8 1.6 2.1 10.7 1.7 3.6 3.5 0.8 2.6 0.1 1.3 3.0 2.0 2.5 1.2 3.7 1.6 1.6 2.7 2.1 6.9 1.6 4.4 1.7 2.5 2.1 1.7 1.6 1.9 3.8 1.4 1.3 3.7 0.3 1.4 0.7 1.1 1.5 4.6 1.5 2.0 1.2 2.5 1.6 0.5 1.1 0.6 0.9 1.2 1.7 0.3 24.1 0.5 3.5 0.6 2.6 2.2 0.6 1.7 0.8 1.0 12.1 0.2 17.7 3.2 4.5 1.0 1.2 1.8 1.5 1.2 1.5 1.8 3.2 3.3 2.8 1.6 6.4 25.4 1.2 3.6 3.0 1.0 0.5 0.4 0.0 1.0 0.9 0.3 0.4 0.5 1.4 0.7 0.3 0.3 0.4 0.7 3.1 0.9 0.0 2.1 0.4 5.1 4.5 2.0 5.4 3.8 2.5 4.7 2.7 2.2 2.1 3.5 2.5 8.0 0.0 1.3 209.6 1.5 5.6 4.2 1.1 4.0 11.2 0.7 1.0 1.4 1.5 1.3 0.0 12.5 3.1 3.8 0.1 0.0 0.9 1.1 1.7 9.6 12.7 1.2 0.0 37.7 2.3 5.6 6.5 0.0 3.6 5.7 1.1 5.3 0.0 5.4 3.3 24.6 0.0 2.0 6.0 25.4 4.1 61.8 7.1 10.6 19.7 1.1 28.9 5.2 30.2 10.7 2.8 0.1 78.6 6.2 2.7 0.0 0.3 0.2 8.2 13.1 11.8 7.1 2.6 1.3 0.8 3.7 2.2 3.0 3.3 0.1 5.2 ANKRD12 "FLJ20053, GAC-1, KIAA0874" ENSG00000101745 "Ankyrin repeat domain 12" Q6UB98 18 9136228-9285985 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 106.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040705 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA040705: AB_10673301" "unprognostic (2.20e-1)" "unprognostic (1.14e-1)" "unprognostic (3.59e-1)" "unprognostic (1.37e-1)" "unprognostic (1.46e-1)" "unprognostic (3.41e-3)" "unprognostic (7.25e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.71e-4)" "unprognostic (1.24e-2)" "unprognostic (1.55e-1)" "unprognostic (3.38e-1)" "unprognostic (2.39e-2)" "unprognostic (4.62e-1)" "unprognostic (1.56e-1)" "unprognostic (3.03e-1)" "unprognostic (1.03e-2)" 15.8 9.3 17.1 20.5 21.4 20.5 13.7 59.9 26.0 11.1 2.2 13.0 12.9 11.8 9.5 14.4 6.2 14.6 11.9 13.9 18.4 13.0 13.8 11.5 22.4 11.2 13.4 14.1 11.9 10.5 5.9 14.1 13.2 12.2 12.0 29.8 12.3 10.6 26.7 20.2 13.4 9.1 10.4 19.9 14.5 27.7 15.8 11.4 16.4 12.3 18.5 13.5 8.0 32.3 10.1 6.7 9.0 6.0 14.2 14.5 7.3 15.3 14.2 5.4 7.4 6.1 7.6 13.9 8.7 10.6 16.4 9.1 6.8 6.0 14.5 14.8 8.1 6.4 4.7 9.0 10.5 15.0 19.7 7.6 13.1 7.7 12.4 12.2 9.2 8.0 14.7 106.4 13.2 5.7 10.1 10.2 3.4 24.7 6.8 9.0 12.6 51.1 7.1 15.8 20.9 7.7 15.0 7.4 11.1 8.0 9.2 12.4 19.9 39.5 18.1 32.1 14.4 30.8 52.0 25.9 19.4 7.9 15.2 102.0 26.4 85.1 42.4 24.1 47.9 63.6 54.9 42.0 19.2 56.2 55.9 43.4 157.3 30.4 37.2 60.6 44.0 18.3 17.1 21.4 59.9 26.0 13.9 18.4 11.2 13.4 13.2 10.4 15.8 32.3 235.1 278.9 261.5 198.5 246.9 108.2 205.9 83.3 116.7 301.0 87.5 108.5 138.6 94.4 137.7 68.0 523.3 46.3 267.2 163.1 19.6 99.7 204.9 144.3 91.9 136.8 92.7 90.7 172.1 83.5 41.1 126.8 64.2 292.9 187.2 76.3 121.7 74.0 67.8 286.0 218.1 90.4 107.8 99.7 126.2 230.9 134.8 149.3 90.7 161.1 178.2 125.5 244.1 184.5 347.4 93.0 147.1 141.4 210.1 196.8 126.1 37.0 88.5 315.4 111.7 173.2 150.0 239.5 152.8 70.9 96.0 78.1 298.3 63.0 71.0 170.7 ANKRD20A1 "ANKRD20A, DKFZp434A171" ENSG00000260691 "Ankyrin repeat domain 20 family member A1" Q5TYW2 9 67832765-67920552 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.3;testis: 4.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.8;Excitatory neurons: 14.8;Inhibitory neurons: 9.0;Oligodendrocyte precursor cells: 12.5;Spermatocytes: 10.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 8.7;U-266/70: 8.7;U-266/84: 5.6" "HPA043239, HPA046346, HPA046695, HPA047112, HPA047167, HPA047766, HPA049923, HPA051288, HPA051753" Uncertain Uncertain "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim" Cytosol "HPA043239: , HPA046346: AB_2679631, HPA046695: , HPA047112: , HPA047167: , HPA047766: , HPA049923: AB_2680954, HPA051288: AB_2681421, HPA051753: AB_2681592" "unprognostic (4.92e-1)" "unprognostic (4.31e-3)" "unprognostic (3.97e-1)" "unprognostic (2.30e-2)" "unprognostic (5.94e-2)" "unprognostic (2.26e-2)" "unprognostic (1.31e-1)" "unprognostic (1.35e-2)" "unprognostic (2.32e-2)" "unprognostic (7.17e-2)" "unprognostic (1.70e-1)" "unprognostic (5.45e-2)" 0.4 0.2 0.8 0.1 2.6 0.5 0.4 0.1 3.3 0.3 0.0 0.4 0.1 0.2 0.3 0.8 0.4 0.2 0.9 1.3 0.2 0.3 0.2 0.5 0.1 0.4 0.1 0.2 1.0 0.2 0.7 0.0 0.7 0.4 0.7 0.8 0.4 0.2 0.1 0.4 0.3 0.2 0.1 0.7 0.1 4.4 0.4 0.3 0.4 0.0 0.0 0.1 0.4 2.9 0.2 0.2 1.3 0.5 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.9 1.4 0.0 0.0 0.3 0.5 0.9 0.3 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.2 0.3 1.4 0.3 8.7 0.0 0.0 0.8 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.6 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.3 0.4 0.8 8.7 5.6 0.0 0.3 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 2.6 0.1 3.3 1.3 0.2 0.4 0.1 0.7 0.1 0.4 2.9 0.0 3.2 2.0 1.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.3 1.2 0.2 0.0 0.8 0.0 0.0 14.8 1.8 0.0 0.3 1.5 0.1 1.3 0.5 0.0 0.0 0.0 0.0 9.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.6 0.0 0.0 12.5 0.3 0.5 2.5 0.0 0.0 0.0 1.8 0.0 2.2 0.0 0.0 0.0 0.2 10.3 1.9 0.7 0.0 0.0 0.4 0.0 1.3 0.1 ANKRD20A3P ANKRD20A3 ENSG00000276203 "Ankyrin repeat domain 20 family member A3, pseudogene" Q5VUR7 9 66106815-66179474 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 2.0" "Cell type enriched" "Detected in single" 15 "Cardiomyocytes: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Karpas-707: 9.5;U-266/84: 3.7" "HPA043239, HPA047112, HPA047167, HPA047766, HPA051753" Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA043239: , HPA047112: , HPA047167: , HPA047766: , HPA051753: AB_2681592" "unprognostic (4.27e-2)" 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.7 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.4 0.2 0.1 0.0 0.1 0.1 0.0 0.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ANKRD20A4P ANKRD20A4 ENSG00000172014 "Ankyrin repeat domain 20 family member A4, pseudogene" Q4UJ75 9 64369394-64413142 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.6" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 9.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 1.0;Karpas-707: 1.4" "HPA043239, HPA047112, HPA047167, HPA047766, HPA051753" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA043239: , HPA047112: , HPA047167: , HPA047766: , HPA051753: AB_2681592" "unprognostic (3.40e-2)" "unprognostic (1.02e-1)" "unprognostic (2.69e-2)" "unprognostic (2.56e-1)" "unprognostic (9.24e-2)" "unprognostic (1.11e-2)" "unprognostic (3.97e-3)" "unprognostic (8.99e-2)" "unprognostic (2.88e-1)" "unprognostic (4.12e-1)" "unprognostic (4.01e-2)" "unprognostic (1.82e-2)" "unprognostic (1.16e-1)" "unprognostic (8.10e-2)" "unprognostic (5.84e-2)" 0.5 0.2 0.4 0.1 0.7 1.1 0.2 0.7 1.6 0.2 0.0 0.3 0.2 0.1 0.1 0.5 0.1 0.1 0.4 0.3 0.3 0.3 0.1 0.3 0.1 0.3 0.1 0.4 0.6 0.1 0.2 0.3 0.5 0.1 0.4 0.5 0.3 0.0 0.2 0.2 0.3 0.0 0.0 0.3 0.3 0.5 0.5 0.2 0.2 0.1 0.0 0.1 0.2 0.7 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.1 0.6 0.1 0.0 0.2 0.5 0.4 0.1 0.2 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.1 0.2 0.9 1.0 1.4 0.0 0.0 0.3 0.0 0.1 0.8 0.3 0.0 0.3 0.2 0.2 0.2 0.6 0.2 0.0 0.0 0.7 0.1 0.7 0.0 0.3 0.0 0.7 0.1 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.7 0.7 1.6 0.3 0.3 0.3 0.1 0.5 0.0 0.5 0.7 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 ANKRD23 "DARP, FLJ32449, MARP3" ENSG00000163126 "Ankyrin repeat domain 23" Q86SG2 2 96824526-96857934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "skeletal muscle: 1438.6;tongue: 448.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 5.0;Respiratory ciliated cells: 7.4;Rod photoreceptor cells: 5.2;Skeletal myocytes: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Karpas-707: 38.5" "Low region specificity" "Detected in many" HPA036201 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Actin filaments" "HPA036201: AB_10673347" "unprognostic (2.48e-1)" "unprognostic (7.83e-4)" "unprognostic (4.93e-4)" "unprognostic (1.21e-2)" "unprognostic (4.28e-1)" "unprognostic (3.28e-1)" "unprognostic (3.27e-2)" "unprognostic (6.66e-2)" "unprognostic (2.46e-2)" "unprognostic (3.59e-2)" "unprognostic (1.81e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-6)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.54e-1)" "unprognostic (2.70e-4)" 0.8 0.9 1.6 0.4 2.1 0.7 1.2 2.2 2.1 1.4 0.6 1.3 0.8 1.8 0.0 6.0 2.5 0.2 24.2 1.5 1.4 0.7 2.2 1.0 0.6 2.5 1.6 1.7 1.6 0.3 10.4 0.2 1.8 5.3 0.1 0.1 18.5 0.3 1438.6 2.5 1.3 0.2 1.5 2.3 0.7 0.7 1.9 0.6 1.1 448.6 0.4 1.2 1.1 2.3 0.5 0.7 0.4 0.8 0.0 0.2 1.1 0.3 0.1 0.2 0.1 0.1 0.2 0.4 0.2 0.1 0.3 0.3 0.3 0.3 0.2 1.1 1.0 0.5 0.8 0.2 0.1 0.8 1.8 0.3 0.3 0.6 0.0 0.2 0.1 1.5 0.9 38.5 0.3 0.9 0.5 0.8 0.4 0.1 0.3 1.4 0.0 5.0 0.2 0.9 1.4 0.2 0.3 0.7 0.0 0.2 1.1 0.0 0.3 0.5 0.6 0.7 0.1 1.7 0.7 0.3 0.4 1.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 2.1 2.2 2.1 1.5 1.4 2.5 1.6 1.8 1.5 1.9 2.3 1.1 0.0 1.1 2.0 0.5 0.8 0.5 0.4 0.6 2.6 0.8 2.3 5.0 0.0 1.5 0.0 2.1 0.4 2.1 0.9 0.0 0.3 3.3 1.3 1.9 0.8 0.0 0.4 2.8 1.1 0.2 1.3 0.5 0.7 1.3 1.1 1.4 1.2 0.2 1.7 2.7 1.0 0.0 0.6 0.3 1.8 1.5 0.6 0.0 1.0 0.2 1.1 1.0 0.5 2.9 0.1 0.3 3.0 0.4 0.3 0.6 0.2 7.4 5.2 0.0 6.1 1.6 1.3 0.4 0.4 1.3 0.3 1.1 0.7 0.9 0.2 ANKRD39 MGC41816 ENSG00000213337 "Ankyrin repeat domain 39" Q53RE8 2 96836611-96858016 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 263.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042678 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm Vesicles "HPA042678: AB_10794532" "unprognostic (6.26e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (2.26e-4)" "unprognostic (9.53e-2)" "unprognostic (2.28e-2)" "unprognostic (2.09e-1)" "unprognostic (4.03e-2)" "unprognostic (1.68e-1)" "unprognostic (9.25e-2)" "unprognostic (3.12e-3)" "prognostic favorable (6.12e-5)" "unprognostic (6.15e-2)" "prognostic unfavorable (6.78e-9)" "unprognostic (3.16e-1)" "unprognostic (1.14e-1)" "unprognostic (5.03e-2)" "prognostic favorable (5.21e-4)" 6.8 14.1 13.1 7.2 13.4 10.5 7.3 15.9 18.7 6.9 8.9 11.0 8.3 10.2 2.9 7.5 10.2 5.9 14.9 13.2 13.2 7.9 14.8 6.2 11.0 13.0 12.5 6.6 8.3 12.3 16.0 5.5 13.4 8.2 4.0 5.3 7.4 6.8 7.9 8.7 7.4 6.2 12.3 9.7 8.3 4.1 12.5 7.4 5.8 4.5 6.5 8.5 6.8 14.5 24.0 15.7 8.8 19.2 2.9 5.7 21.1 18.1 8.4 22.5 17.3 38.8 9.9 15.2 26.4 13.2 17.7 10.3 11.2 17.3 5.0 17.6 34.1 11.0 14.4 53.5 14.8 24.9 25.6 11.0 10.2 20.5 7.9 8.4 16.3 31.1 23.5 263.1 8.4 37.9 23.3 19.5 11.1 8.1 35.8 17.8 6.2 85.3 11.8 12.3 20.3 13.3 13.1 30.6 23.7 8.0 9.3 13.5 8.2 14.0 13.8 16.0 32.5 13.4 16.2 25.3 14.0 28.5 14.9 20.1 16.0 13.4 44.4 20.8 37.7 41.6 43.6 39.3 16.6 33.2 24.0 29.2 8.3 37.6 23.5 70.4 71.0 21.1 13.1 13.4 15.9 18.7 13.2 13.2 13.0 12.5 13.4 12.3 12.5 14.5 14.0 6.4 8.9 2.6 16.9 9.4 17.2 25.7 9.1 25.2 14.9 23.2 19.5 18.6 17.6 9.2 4.2 44.9 28.1 15.1 25.4 28.8 6.1 18.1 18.7 12.9 18.6 13.5 4.6 32.0 38.6 14.9 11.7 11.8 12.7 12.7 10.8 32.0 31.6 33.7 5.3 19.9 18.3 11.1 10.4 2.9 12.5 13.8 28.4 1.0 9.3 15.9 37.0 4.5 5.9 41.3 11.3 14.7 26.2 12.5 23.4 29.4 35.0 29.8 26.3 24.9 18.8 13.6 14.3 18.9 17.8 21.6 24.4 33.5 16.9 15.7 AP001267.5 ENSG00000285827 "Novel protein" 11 118401602-118482737 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Alveolar cells type 2: 24.1;Club cells: 14.9;granulocytes: 20.2;Respiratory ciliated cells: 13.8" "Region enhanced" "Detected in many" "cerebellum: 3.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA044629 Uncertain Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA044629: AB_2679028" 1.2 1.2 0.7 1.5 0.9 7.2 1.3 3.8 1.3 0.8 0.4 1.3 1.8 0.8 1.1 0.6 0.8 0.7 1.2 0.7 1.4 1.2 1.2 0.9 2.4 0.2 0.1 0.8 0.8 1.6 0.7 0.2 1.4 1.2 1.5 1.4 0.8 1.5 0.5 1.8 0.8 0.0 1.0 1.4 0.7 0.2 2.6 1.1 1.8 1.3 1.0 1.6 3.1 0.7 2.0 2.7 0.9 0.8 3.8 1.5 1.2 1.9 1.9 3.3 2.5 2.6 3.6 1.9 4.0 2.4 2.8 2.4 2.8 4.0 1.8 4.3 1.2 1.6 1.8 2.9 3.0 1.4 1.3 2.3 3.0 1.2 2.4 6.1 3.4 6.7 1.7 2.4 4.5 5.7 1.7 5.5 2.6 3.9 2.2 3.4 3.4 1.2 3.3 2.3 2.4 1.2 1.5 3.0 1.9 1.5 1.3 2.0 4.2 1.1 1.9 1.7 1.6 5.2 0.7 3.1 1.0 5.5 5.1 6.0 4.9 4.2 4.1 6.1 4.4 4.0 5.0 5.1 4.2 4.0 4.1 3.7 4.0 7.2 5.8 10.6 0.7 0.9 3.8 1.3 0.7 1.4 0.2 0.1 0.2 0.0 0.2 1.6 0.0 16.0 24.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 AP3D1 ADTD ENSG00000065000 "Adaptor related protein complex 3 subunit delta 1" O14617 19 2100988-2164468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074408 Approved Cytosol No No 28000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA074408: AB_2686686" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.24e-3)" "unprognostic (1.37e-1)" "unprognostic (6.35e-2)" "prognostic unfavorable (9.23e-4)" "unprognostic (4.24e-2)" "unprognostic (8.05e-2)" "unprognostic (5.70e-2)" "unprognostic (6.68e-3)" "unprognostic (9.37e-2)" "prognostic favorable (2.61e-6)" "unprognostic (8.11e-3)" "unprognostic (1.22e-1)" "unprognostic (6.25e-2)" "unprognostic (1.73e-2)" 30.0 40.7 39.0 36.3 39.0 27.6 28.8 29.4 55.1 29.5 39.4 36.2 35.8 35.1 16.6 38.2 32.5 28.0 43.7 45.0 39.8 35.8 40.9 31.1 37.2 39.4 43.3 29.8 63.9 40.0 56.4 33.4 48.0 31.3 22.5 29.6 48.0 34.0 61.1 30.0 35.4 32.8 26.0 34.8 37.7 44.9 38.9 33.2 43.9 40.3 27.6 34.3 25.5 34.5 114.8 117.5 68.5 105.0 85.7 71.8 83.9 90.3 87.9 94.2 85.2 134.8 61.8 61.7 51.0 134.1 115.7 76.4 99.2 109.7 61.1 89.9 94.6 80.5 74.7 106.3 149.9 88.4 102.5 89.5 72.3 98.1 141.6 79.7 92.6 44.2 84.2 210.9 84.1 84.4 85.6 46.8 102.8 78.2 74.2 90.3 75.0 83.4 70.7 162.7 97.4 81.1 82.3 85.7 154.2 62.5 83.2 101.0 121.7 89.7 37.7 123.4 106.7 176.5 184.6 78.6 122.5 57.4 91.5 0.2 3.3 2.9 3.5 3.6 5.6 2.4 3.4 4.1 3.9 2.9 2.7 3.4 3.4 5.5 3.0 7.5 2.1 2.2 39.0 39.0 29.4 55.1 45.0 39.8 39.4 43.3 48.0 26.0 38.9 34.5 29.5 60.9 61.7 41.4 35.5 20.3 41.3 20.3 36.5 66.6 39.5 26.5 77.7 44.3 34.1 40.5 35.5 55.3 32.5 79.5 21.5 53.3 70.7 34.4 36.9 37.1 47.8 42.9 24.1 74.2 71.9 38.2 69.8 48.9 17.1 38.9 29.6 49.2 66.9 48.8 30.2 68.8 18.3 38.4 30.2 68.6 37.9 43.4 39.2 18.7 31.7 55.5 29.9 21.1 28.3 67.7 54.0 38.0 67.6 65.5 52.6 36.0 30.3 43.9 19.7 37.8 33.6 105.3 129.5 38.0 23.3 78.0 36.9 39.6 56.8 59.4 APOBEC3B "FLJ21201, PHRBNL" ENSG00000179750 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3B" Q9UH17 22 38982347-38992804 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.4;intestine: 12.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 11.8;Ductal cells: 14.7;Erythroid cells: 14.1;Plasma cells: 26.2;Urothelial cells: 11.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 256.0;Karpas-707: 283.6" "HPA056980, HPA066719" Approved Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA056980: AB_2683298, HPA066719: AB_2685711" "unprognostic (2.92e-2)" "prognostic favorable (2.58e-5)" "unprognostic (4.29e-2)" "unprognostic (1.19e-1)" "unprognostic (2.50e-1)" "unprognostic (1.35e-1)" "unprognostic (1.69e-2)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (6.36e-2)" "unprognostic (1.08e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (8.47e-2)" "unprognostic (2.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.04e-1)" 0.9 1.2 0.1 5.7 0.1 28.4 2.0 0.1 0.2 1.2 0.1 12.1 7.3 1.0 0.4 3.0 0.7 1.1 0.8 0.1 0.1 2.7 1.1 1.9 5.9 0.1 0.1 0.7 3.3 1.2 0.2 1.6 0.1 0.4 12.0 0.3 2.8 0.2 0.4 2.1 4.3 1.4 0.1 6.4 4.1 0.3 0.2 2.5 1.3 0.2 8.6 7.6 1.5 0.2 256.0 28.0 10.5 68.1 1.5 6.0 18.6 23.0 19.7 43.0 56.5 54.7 46.6 3.0 20.4 22.9 63.0 108.2 1.3 4.5 43.1 92.1 2.5 72.5 5.6 14.0 0.7 61.7 43.0 2.3 0.5 45.1 2.2 8.9 17.0 0.0 41.6 283.6 68.1 6.9 0.2 35.3 0.3 24.6 25.2 1.8 105.0 95.6 9.1 42.2 1.8 0.0 0.0 0.3 16.0 1.8 33.0 18.1 10.2 48.0 81.9 7.5 0.7 62.8 18.0 0.3 34.4 68.2 100.7 0.4 1.0 0.0 0.2 4.9 0.0 7.2 0.5 0.3 0.6 3.1 0.0 0.3 1.4 1.7 1.7 0.0 2.8 3.5 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.0 1.7 0.0 2.2 5.4 3.2 11.8 0.6 0.0 1.5 0.5 0.3 0.0 8.1 0.0 0.0 1.0 0.4 4.6 0.0 14.7 0.0 5.9 0.6 0.2 0.0 14.1 0.0 1.8 1.8 0.8 3.1 5.3 0.0 0.8 0.4 0.0 2.1 0.0 0.0 0.4 10.2 1.2 6.3 0.0 0.0 2.3 7.2 0.0 1.4 0.0 0.0 0.0 0.0 6.0 9.9 0.0 26.2 1.4 0.4 0.3 9.3 0.0 0.0 0.0 0.9 0.0 0.0 4.2 3.3 0.8 0.5 0.1 1.6 11.4 APOBEC3C "APOBEC1L, ARDC2, ARDC4, ARP5, bK150C2.3, PBI" ENSG00000244509 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3C" Q9NRW3 22 39014257-39020352 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB033048, HPA071523" Approved Approved "Intermediate filaments" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Intermediate filaments" "CAB033048: AB_2057401, HPA071523: AB_2686409" "unprognostic (1.79e-3)" "prognostic favorable (1.08e-5)" "unprognostic (4.32e-3)" "unprognostic (3.20e-3)" "unprognostic (4.68e-2)" "unprognostic (2.13e-1)" "unprognostic (5.18e-2)" "unprognostic (2.55e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-3)" "unprognostic (7.40e-2)" "unprognostic (4.10e-2)" "prognostic unfavorable (8.91e-10)" "unprognostic (5.92e-2)" "unprognostic (1.11e-1)" "unprognostic (4.10e-1)" "unprognostic (3.52e-3)" 12.3 36.2 3.1 31.1 3.2 31.4 12.3 3.1 4.0 23.1 3.5 20.2 14.0 22.6 51.7 22.7 56.0 18.4 24.0 3.0 3.5 6.0 7.0 20.6 57.8 5.0 3.6 38.2 5.1 10.5 3.8 11.6 5.1 25.9 33.1 3.4 22.1 36.1 2.7 19.8 17.4 30.8 4.5 36.5 18.1 29.4 3.9 25.2 15.2 11.3 67.8 27.6 17.3 6.5 39.4 38.1 6.3 73.9 40.2 82.6 32.4 28.3 54.9 41.0 54.5 36.8 43.7 115.5 18.6 56.1 26.2 39.4 6.5 120.2 39.5 44.3 32.0 111.8 1.6 30.6 43.5 73.4 107.1 90.5 68.1 54.0 13.3 20.4 23.0 0.9 69.9 142.3 83.0 0.4 29.6 39.8 9.8 0.5 82.8 51.1 16.9 96.6 27.2 51.4 1.9 4.9 40.9 0.2 21.7 15.9 0.2 26.8 11.9 21.8 37.1 11.9 12.4 38.6 42.7 9.5 66.9 47.1 58.8 86.6 104.4 277.0 309.1 220.6 212.6 241.6 164.7 276.9 106.9 249.1 54.0 196.9 14.1 196.9 247.8 86.9 168.9 173.6 3.1 3.2 3.1 4.0 3.0 3.5 5.0 3.6 5.1 4.5 3.9 6.5 3.3 3.2 16.2 0.0 68.8 25.2 45.4 44.1 24.5 0.2 16.4 8.9 23.0 28.6 18.4 7.3 0.0 4.3 60.2 56.6 0.0 31.6 3.2 11.0 16.4 9.6 26.4 57.2 0.0 1.3 1.4 26.5 5.6 15.6 57.0 78.6 30.0 1.2 61.9 0.0 0.0 17.8 28.5 49.0 37.3 9.3 57.8 34.2 44.4 0.0 65.1 24.4 117.4 0.5 0.0 11.5 16.6 38.0 55.4 18.9 3.2 1.3 13.6 0.8 26.3 11.9 20.1 1.5 1.5 9.7 16.3 1.9 67.7 53.5 18.8 41.9 APOBEC3D "APOBEC3DE, APOBEC3E, ARP6" ENSG00000243811 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3D" Q96AK3 22 39021113-39033277 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.3" "Cell type enhanced" "Detected in many" "B-cells: 6.7;NK-cells: 9.2;Plasma cells: 6.4;T-cells: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 11.8;Karpas-707: 46.7" HPA055116 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA055116: AB_2682701" "prognostic favorable (2.51e-5)" "prognostic favorable (1.31e-4)" "unprognostic (2.69e-2)" "prognostic favorable (4.47e-4)" "unprognostic (2.62e-2)" "unprognostic (3.06e-2)" "unprognostic (2.46e-1)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (2.45e-2)" "unprognostic (4.50e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (3.76e-7)" "unprognostic (4.76e-2)" "unprognostic (6.00e-2)" "unprognostic (1.06e-2)" "prognostic favorable (3.01e-4)" 1.7 2.2 1.2 8.6 1.2 2.5 1.8 1.5 1.2 3.5 1.1 3.5 3.8 3.3 3.0 1.7 5.2 4.1 1.2 1.0 0.9 1.6 1.2 3.3 15.3 1.6 1.2 4.1 0.5 1.1 0.9 2.2 1.3 2.6 4.3 0.3 2.8 2.3 0.9 1.4 5.3 2.4 1.3 12.0 5.3 2.4 1.1 7.7 1.9 1.2 13.8 4.6 2.7 1.4 0.5 0.0 0.3 2.1 3.1 5.5 1.9 0.3 3.3 3.9 4.4 0.9 5.3 6.1 0.9 4.4 2.5 0.6 0.3 0.0 1.4 11.1 1.2 10.7 0.1 0.0 8.3 1.5 11.8 3.6 0.5 6.3 0.0 0.0 2.9 9.0 2.7 46.7 0.2 0.0 5.2 3.4 0.8 0.0 0.5 4.3 0.3 0.1 0.0 0.0 0.1 0.3 0.2 0.1 1.7 1.4 0.1 0.5 1.1 0.1 1.2 0.6 0.0 3.2 3.9 0.8 1.6 3.3 1.5 4.8 1.3 3.5 8.0 3.5 5.2 6.7 5.8 7.3 0.8 6.8 2.7 3.6 1.7 4.9 6.5 5.4 5.8 3.4 1.2 1.2 1.5 1.2 1.0 0.9 1.6 1.2 1.3 1.3 1.1 1.4 0.9 3.2 0.5 0.0 6.7 1.0 1.5 0.9 0.0 0.2 0.3 0.6 0.4 5.7 1.1 1.8 0.0 1.3 3.8 3.0 0.0 0.2 0.5 1.0 0.8 1.9 1.8 1.7 0.0 0.2 0.7 1.8 2.6 0.6 0.0 1.1 2.5 0.2 2.5 0.0 0.0 3.6 0.0 3.4 1.0 0.0 3.1 1.1 3.6 2.8 1.2 0.3 9.2 0.5 0.0 0.2 0.1 1.9 6.4 1.4 1.3 0.3 2.7 0.5 0.0 0.9 1.4 0.2 0.4 0.2 0.9 0.5 8.7 0.8 2.1 2.6 APOBEC3F "ARP8, BK150C2.4.MRNA, KA6" ENSG00000128394 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3F" Q8IUX4 22 39040604-39055972 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 19.9" HPA073637 Uncertain Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA073637: " "unprognostic (1.38e-3)" "unprognostic (1.28e-3)" "unprognostic (4.63e-2)" "unprognostic (1.63e-2)" "unprognostic (6.16e-2)" "unprognostic (3.51e-2)" "unprognostic (3.90e-2)" "unprognostic (1.42e-1)" "unprognostic (6.03e-2)" "unprognostic (1.34e-2)" "unprognostic (1.57e-1)" "unprognostic (1.88e-1)" "unprognostic (2.06e-3)" "unprognostic (9.36e-2)" "unprognostic (3.21e-2)" "unprognostic (1.49e-1)" "prognostic favorable (8.28e-4)" 2.2 6.3 2.2 9.2 2.1 3.3 2.5 2.2 2.7 4.0 3.4 3.5 3.7 4.1 6.3 2.4 8.3 3.5 5.5 2.0 2.2 3.4 2.9 3.4 15.7 3.1 2.6 8.8 3.0 5.2 3.4 2.2 2.8 4.8 2.8 1.1 4.9 5.2 0.6 1.6 3.8 4.5 2.3 11.9 4.8 8.2 2.5 5.3 3.0 1.3 14.5 4.5 3.2 2.9 4.9 4.2 1.8 6.2 4.9 7.1 2.2 4.2 6.9 8.8 14.0 3.9 9.1 12.9 4.1 8.9 7.7 6.5 1.7 6.0 3.8 11.7 5.3 16.5 0.5 2.5 8.6 3.6 7.0 9.5 3.0 5.0 1.5 5.1 8.5 3.5 1.3 19.9 4.8 3.9 4.0 2.7 0.8 0.5 0.7 6.1 0.7 2.5 8.1 6.6 0.9 1.5 4.7 1.2 2.5 3.5 4.7 1.9 2.3 2.0 5.0 0.4 2.0 3.4 1.7 0.5 5.6 1.9 3.1 3.2 4.7 9.4 8.5 9.1 9.8 27.7 5.6 9.0 6.0 34.2 3.4 5.6 3.1 14.6 14.5 4.6 8.4 7.4 2.2 2.1 2.2 2.7 2.0 2.2 3.1 2.6 2.8 2.3 2.5 2.9 1.6 0.0 0.5 0.0 9.8 0.9 4.9 6.3 2.2 0.0 2.1 2.2 5.9 8.6 4.2 0.0 0.0 2.0 7.6 0.8 1.9 7.4 2.4 4.8 3.8 2.6 1.2 2.1 0.1 3.9 1.4 2.9 2.6 3.6 2.5 11.0 3.6 1.6 5.9 0.0 0.0 2.2 4.1 2.2 1.4 5.2 5.0 2.8 5.4 2.8 5.3 2.2 8.2 0.5 0.0 4.8 3.6 6.4 9.6 4.5 0.5 5.3 4.6 0.2 0.0 1.0 2.6 0.3 0.4 1.6 0.9 1.6 5.4 7.8 1.5 5.9 APOBEC3G "bK150C2.7, CEM15, dJ494G10.1, FLJ12740, MDS019" ENSG00000239713 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3G" Q9HC16 22 39077067-39087743 "Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 45.9" "Cell type enhanced" "Detected in many" "dendritic cells: 145.4;monocytes: 69.1;NK-cells: 251.3;Plasma cells: 69.5;T-cells: 120.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 30.0;Daudi: 38.3;HDLM-2: 31.8;Karpas-707: 44.2" "HPA001812, HPA073637" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA001812: AB_1078175, HPA073637: " "prognostic favorable (4.78e-4)" "prognostic favorable (4.70e-4)" "unprognostic (8.18e-3)" "prognostic favorable (6.03e-5)" "unprognostic (2.37e-1)" "unprognostic (3.43e-1)" "unprognostic (7.77e-2)" "unprognostic (2.33e-1)" "unprognostic (4.23e-1)" "unprognostic (4.13e-3)" "unprognostic (9.13e-3)" "unprognostic (1.81e-1)" "prognostic unfavorable (8.66e-13)" "unprognostic (3.41e-2)" "unprognostic (5.83e-2)" "unprognostic (2.91e-2)" "prognostic favorable (6.30e-4)" 5.5 8.1 3.3 21.7 3.2 15.9 8.6 3.4 4.6 7.7 2.9 7.6 5.5 10.3 10.4 6.1 21.1 11.1 4.3 3.0 4.0 4.1 5.7 14.5 45.9 3.9 3.7 22.7 1.7 4.8 3.5 5.0 3.9 7.8 9.4 1.4 8.5 22.4 1.2 1.6 9.6 9.6 4.0 28.2 10.0 20.1 3.4 25.9 5.8 2.7 35.1 15.7 6.4 4.5 4.5 0.1 0.0 0.0 5.0 9.7 0.3 1.0 16.8 19.9 30.0 1.6 22.6 38.3 0.5 7.3 11.6 0.1 0.2 1.3 6.0 31.8 0.1 23.1 0.0 0.2 21.8 7.1 10.1 14.3 0.5 10.9 2.4 0.0 2.4 1.2 1.9 44.2 3.1 0.0 7.6 7.7 0.6 0.0 1.7 15.3 0.0 25.8 0.0 19.6 0.0 0.0 0.5 0.0 2.0 1.7 0.0 13.2 0.0 2.8 0.2 0.0 0.0 0.0 3.5 0.5 3.2 6.9 5.0 30.7 42.3 28.7 363.8 98.1 207.6 84.9 108.8 281.7 52.4 66.1 34.3 160.2 34.8 232.2 123.0 28.1 92.3 297.8 3.3 3.2 3.4 4.6 3.0 4.0 3.9 3.7 3.9 4.0 3.4 4.5 8.4 3.2 8.9 1.0 55.7 1.8 15.5 27.0 4.6 0.4 3.0 6.6 3.7 7.2 14.4 0.0 2.1 3.9 145.4 0.6 5.9 11.7 47.2 5.7 6.4 8.9 6.0 8.6 0.1 2.3 1.1 10.0 2.0 3.9 12.6 62.5 11.4 0.9 30.6 0.0 0.1 1.9 10.2 20.4 9.8 13.7 19.0 21.3 7.2 3.7 69.1 8.1 251.3 0.5 0.0 2.2 1.8 9.1 69.5 16.0 0.1 2.1 12.1 1.2 19.7 4.7 10.1 1.3 1.6 2.0 1.3 1.0 120.5 20.3 1.5 18.0 APOBEC3H ARP10 ENSG00000100298 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3H" Q6NTF7 22 39097224-39104067 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.6;dendritic cells: 9.6;Hofbauer cells: 4.9;monocytes: 10.5;NK-cells: 6.2;T-cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 9 "gdT-cell: 23.2;MAIT T-cell: 9.4;memory CD4 T-cell: 12.1;memory CD8 T-cell: 19.4;naive CD8 T-cell: 8.9;NK-cell: 19.7;T-reg: 11.9" "Group enriched" "Detected in many" 13 "NK-cells: 19.7;T-cells: 23.2" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HDLM-2: 2.7;Karpas-707: 6.9;U-266/70: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021492, HPA058565" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA021492: AB_10964888, HPA058565: " "unprognostic (7.09e-3)" "prognostic favorable (1.20e-4)" "unprognostic (1.05e-1)" "unprognostic (6.81e-4)" "unprognostic (3.40e-1)" "unprognostic (1.54e-3)" "unprognostic (2.30e-2)" "unprognostic (1.36e-2)" "unprognostic (2.17e-1)" "unprognostic (3.83e-2)" "unprognostic (5.07e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (8.73e-12)" "unprognostic (1.05e-1)" "unprognostic (1.03e-1)" "unprognostic (6.55e-3)" "prognostic favorable (8.43e-7)" 0.7 0.8 0.3 2.3 0.5 3.6 0.6 1.0 0.7 0.7 0.0 1.8 0.5 0.8 3.6 1.1 1.3 1.6 0.5 0.3 0.3 0.8 0.6 2.4 3.8 0.7 0.4 0.5 0.3 0.6 0.7 1.0 0.6 0.7 3.3 0.6 0.9 1.5 0.6 0.5 1.2 1.2 0.2 3.1 0.9 1.6 0.5 2.9 0.7 0.0 2.1 1.4 0.6 0.5 0.0 0.5 0.0 0.0 0.0 0.2 2.0 0.0 0.1 0.2 0.0 0.0 0.2 2.8 1.0 0.3 0.0 0.1 0.0 0.6 0.0 2.7 0.3 0.7 0.1 0.0 0.2 0.0 2.0 1.8 1.6 0.2 0.2 0.2 0.0 0.1 0.0 6.9 0.9 0.9 1.4 0.2 0.0 0.0 0.0 1.6 0.0 0.2 0.0 1.3 0.0 0.0 0.1 0.0 0.0 1.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 4.8 0.7 0.2 0.2 1.2 0.1 0.1 0.3 0.0 23.2 0.5 9.4 1.4 12.1 19.4 0.2 0.4 0.6 8.9 0.0 19.7 1.6 0.0 11.9 4.7 0.3 0.5 1.0 0.7 0.3 0.3 0.7 0.4 0.6 0.2 0.5 0.5 0.4 0.0 4.2 0.0 1.6 0.1 0.6 0.9 1.2 0.0 0.2 0.3 0.1 0.0 2.4 0.0 0.0 6.6 9.6 0.1 0.0 0.2 0.0 0.2 0.1 0.3 0.0 0.4 0.3 0.0 0.6 0.1 0.5 0.1 3.8 0.1 0.4 0.2 4.9 0.0 0.2 0.0 2.0 1.0 0.6 0.5 0.0 1.0 0.0 0.0 10.5 0.0 6.2 0.0 0.1 0.0 0.0 0.0 2.7 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.9 0.1 0.2 0.2 0.0 1.5 20.8 0.0 0.0 0.5 APOL3 "APOLIII, CG12-1" ENSG00000128284 "Apolipoprotein L3" O95236 22 36140330-36166177 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 59.1;Endothelial cells: 69.8;Hepatic stellate cells: 69.7;Kupffer cells: 38.7;NK-cells: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 34.1;ASC TERT1: 54.1;HDLM-2: 25.6;Karpas-707: 59.0" "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "prognostic favorable (6.82e-4)" "unprognostic (5.93e-3)" "unprognostic (6.79e-2)" "unprognostic (2.70e-2)" "unprognostic (2.22e-1)" "unprognostic (7.05e-2)" "unprognostic (6.30e-2)" "unprognostic (2.67e-1)" "unprognostic (8.94e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (7.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" 58.2 12.3 10.1 25.4 10.0 10.1 43.7 8.7 12.2 17.2 7.6 16.3 15.0 18.8 12.3 12.0 24.4 14.3 33.7 8.8 9.1 19.0 39.9 42.0 43.4 11.4 10.1 9.6 6.3 3.4 8.5 16.3 10.0 18.4 11.4 0.6 15.7 14.9 16.6 19.6 21.7 16.0 8.8 47.6 12.3 2.9 10.8 18.1 25.2 19.6 20.8 17.6 19.5 8.7 4.3 0.0 0.0 0.1 34.1 54.1 1.8 1.8 10.2 3.1 7.0 0.0 9.5 2.1 0.4 5.0 4.6 0.7 0.0 1.3 1.9 25.6 0.0 9.2 1.3 2.1 18.3 0.1 2.6 11.4 0.0 9.0 0.4 2.1 22.1 2.0 0.2 59.0 1.1 0.1 11.7 0.3 0.1 0.0 0.5 16.9 0.0 1.3 0.3 3.0 0.2 0.1 6.0 4.2 0.1 0.0 0.0 1.2 16.2 1.5 0.6 1.7 0.5 15.6 10.8 0.1 3.7 3.5 1.5 8.3 19.1 0.8 16.9 23.4 27.3 9.7 14.4 17.5 15.4 8.0 13.4 14.3 2.3 18.5 24.6 0.5 14.7 17.2 10.1 10.0 8.7 12.2 8.8 9.1 11.4 10.1 10.0 8.8 10.8 8.7 59.1 3.2 8.6 1.6 21.1 5.0 4.3 3.9 2.2 0.0 5.8 4.2 7.9 8.6 4.3 3.7 0.0 1.9 16.0 0.3 0.0 2.5 0.9 1.8 4.7 69.8 0.0 20.6 0.0 1.6 1.2 18.8 7.1 1.3 9.5 2.0 69.7 20.6 6.9 0.0 0.0 7.5 2.0 38.7 10.6 1.4 24.2 19.6 3.6 9.4 29.2 0.7 46.4 0.0 0.0 3.0 0.1 9.8 15.3 10.4 5.3 2.8 4.2 0.3 13.1 3.2 10.1 0.2 0.3 4.1 4.1 0.8 31.5 4.3 2.3 4.7 ARF6 ENSG00000165527 "ADP ribosylation factor 6" P62330 14 49893082-49897054 "Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 716.1;Suprabasal keratinocytes: 673.3;Urothelial cells: 703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002778, CAB079914" Approved Supported Cytosol NA NA 310000 "Cluster 44: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB002778: , CAB079914: AB_2539861" "unprognostic (1.21e-1)" "unprognostic (2.75e-3)" "unprognostic (1.80e-1)" "unprognostic (7.02e-2)" "unprognostic (2.85e-1)" "unprognostic (1.83e-1)" "unprognostic (4.12e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (3.10e-5)" "unprognostic (1.61e-1)" "unprognostic (1.67e-1)" "unprognostic (8.37e-3)" "unprognostic (1.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.49e-2)" 32.1 25.3 13.4 43.6 14.2 83.1 32.6 15.2 15.3 35.7 16.3 53.4 46.4 21.7 26.6 108.2 28.3 32.8 18.3 11.8 14.3 29.7 46.1 31.5 62.0 14.7 14.3 15.3 24.7 20.4 12.6 36.3 15.4 32.2 51.0 13.2 36.3 19.2 26.1 66.0 51.2 23.8 15.6 49.6 46.7 15.8 15.9 45.2 21.1 17.1 66.7 46.8 55.7 15.6 141.5 58.2 38.4 44.8 51.5 68.4 78.3 86.5 62.6 60.3 62.2 42.6 96.2 91.3 43.7 72.7 46.3 101.7 43.7 69.3 71.3 181.4 34.9 47.2 30.6 38.3 58.1 87.2 60.7 53.7 81.5 48.9 93.7 72.1 67.6 58.3 45.9 176.9 84.7 101.5 77.7 76.5 42.0 75.9 82.8 59.4 50.1 53.9 157.6 112.9 56.4 37.4 68.9 102.3 89.0 46.5 78.0 70.0 90.0 111.9 57.4 66.7 66.1 94.3 104.4 68.6 40.1 50.9 81.3 34.2 20.7 21.1 34.7 33.0 37.6 33.5 33.7 35.3 23.9 26.6 23.0 29.6 14.7 29.1 31.4 15.8 36.2 23.4 13.4 14.2 15.2 15.3 11.8 14.3 14.7 14.3 15.4 15.6 15.9 15.6 102.9 51.3 29.9 2.9 233.7 599.8 529.1 47.9 231.6 22.9 154.4 80.1 18.5 127.2 47.6 101.2 2.1 152.7 298.8 276.0 158.5 125.4 5.8 95.6 98.5 117.1 99.3 140.1 5.3 80.0 208.1 94.9 115.7 143.7 79.9 40.3 108.5 143.3 168.0 33.7 5.9 167.0 20.3 195.6 716.1 8.3 33.5 184.5 304.1 15.0 204.9 42.2 192.6 6.0 8.9 130.4 161.6 32.7 182.4 443.4 190.8 166.5 30.3 21.6 46.0 68.8 90.7 62.7 48.7 361.4 673.3 202.9 311.0 52.6 182.5 703.8 ARFGAP3 ARFGAP1 ENSG00000242247 "ADP ribosylation factor GTPase activating protein 3" Q9NP61 22 42796502-42858106 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000638 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Golgi apparatus" "HPA000638: AB_1078188" "unprognostic (3.29e-2)" "unprognostic (6.08e-2)" "unprognostic (3.22e-1)" "prognostic favorable (8.97e-6)" "unprognostic (5.83e-2)" "unprognostic (8.85e-3)" "unprognostic (5.00e-3)" "unprognostic (1.00e-1)" "unprognostic (2.05e-1)" "unprognostic (1.31e-1)" "unprognostic (9.06e-3)" "unprognostic (1.67e-1)" "unprognostic (1.87e-1)" "unprognostic (2.52e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.65e-4)" "unprognostic (1.73e-1)" 30.1 88.9 16.5 34.1 17.4 47.8 30.9 19.5 20.4 56.1 23.2 26.9 36.5 32.2 53.3 22.1 22.9 36.6 23.6 17.9 20.6 53.2 49.2 32.3 28.1 20.5 18.7 20.7 85.8 38.0 38.1 34.8 20.3 64.7 30.6 35.5 68.5 40.2 31.3 20.7 51.1 30.8 19.0 26.0 43.2 49.5 19.6 25.9 61.3 21.8 32.6 45.2 23.4 21.0 59.6 19.3 41.1 24.7 57.2 94.1 17.3 111.8 76.4 50.5 60.9 23.5 32.8 30.1 24.5 102.9 41.8 14.4 18.7 33.0 54.7 18.5 25.4 35.7 27.6 37.4 79.6 31.9 53.2 42.0 57.6 42.6 75.9 71.9 52.4 27.4 16.1 132.0 89.6 15.7 49.4 17.5 6.7 32.7 23.2 31.1 92.3 38.3 80.7 27.5 14.6 9.0 54.3 21.5 46.0 30.6 22.7 24.4 67.0 58.7 42.5 52.1 30.7 94.7 48.2 33.1 41.9 34.0 46.7 86.2 33.2 36.8 45.1 44.4 58.8 27.1 29.7 39.8 32.5 26.1 19.2 27.2 50.8 49.4 50.9 53.1 28.8 30.1 16.5 17.4 19.5 20.4 17.9 20.6 20.5 18.7 20.3 19.0 19.6 21.0 40.8 38.5 54.8 27.4 41.7 26.6 86.9 43.0 19.9 42.8 43.1 29.5 26.5 37.1 62.1 57.0 18.8 18.8 67.3 36.4 66.5 65.9 19.1 60.5 89.9 42.4 49.1 17.5 26.1 64.3 23.7 58.1 30.1 96.3 65.9 28.4 30.4 37.3 28.7 33.7 28.8 53.0 46.8 21.7 89.3 15.0 48.1 68.2 69.4 35.6 33.7 40.5 38.1 43.7 40.0 83.0 15.6 45.5 110.0 121.5 70.9 62.9 65.5 33.7 39.5 80.0 65.5 178.7 67.6 14.6 26.7 59.9 49.6 39.0 22.7 86.7 ARHGAP21 "ARHGAP10, KIAA1424" ENSG00000107863 "Rho GTPase activating protein 21" Q5T5U3 10 24583609-24723887 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 111.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 266.5;Oligodendrocyte precursor cells: 336.7;Oligodendrocytes: 827.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036610, HPA057861" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Cell Junctions, Actin filaments" "Plasma membrane" "HPA036610: AB_10669910, HPA057861: AB_2683546" "unprognostic (7.65e-2)" "unprognostic (1.61e-2)" "unprognostic (1.88e-1)" "unprognostic (5.84e-2)" "unprognostic (2.69e-1)" "unprognostic (3.59e-1)" "unprognostic (1.12e-3)" "unprognostic (5.35e-2)" "unprognostic (9.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-3)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" "unprognostic (1.53e-1)" "unprognostic (3.32e-1)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" 28.4 18.0 44.3 10.3 77.7 7.2 16.1 56.7 58.1 19.7 0.0 16.6 12.9 19.9 8.6 10.8 17.5 17.9 21.2 49.1 48.3 11.0 13.1 21.7 5.3 76.3 63.1 31.9 14.9 14.6 12.1 16.6 66.7 10.8 18.5 41.3 24.5 11.5 17.7 6.8 16.3 17.8 48.4 8.9 27.1 14.6 58.0 11.4 12.8 23.0 6.0 13.8 9.0 111.2 59.0 25.1 60.9 52.3 42.2 59.1 21.6 41.6 26.6 24.5 34.0 18.4 36.8 10.9 14.0 64.3 37.7 38.1 31.6 40.4 35.9 38.0 20.5 64.9 54.7 13.8 25.5 0.0 9.9 24.4 45.0 32.1 34.4 36.9 42.3 16.1 27.9 96.3 50.0 11.6 30.2 2.3 9.7 20.8 13.6 7.0 21.4 6.2 17.2 10.2 10.5 10.9 27.9 16.0 32.6 18.1 16.3 9.1 47.8 35.3 22.7 40.0 30.6 11.0 20.3 7.8 36.2 11.4 24.7 0.9 0.2 0.4 0.1 0.4 0.1 0.0 0.2 0.3 0.3 0.0 0.6 0.3 0.0 0.2 0.2 0.4 0.4 0.2 44.3 77.7 56.7 58.1 49.1 48.3 76.3 63.1 66.7 48.4 58.0 111.2 47.9 86.6 33.1 246.8 6.5 29.6 13.2 23.6 14.8 144.0 17.5 26.0 37.4 24.3 45.0 5.5 68.8 23.8 6.9 44.6 1.9 21.4 5.0 36.2 148.7 34.9 16.2 15.2 266.5 27.6 21.0 73.0 82.0 54.2 17.1 135.8 26.0 20.9 14.6 132.9 153.8 28.3 14.2 32.8 31.8 8.3 92.9 38.9 19.6 171.4 11.0 194.0 2.1 336.7 827.4 37.1 34.6 59.5 15.2 27.4 21.9 6.5 30.3 53.5 26.3 60.4 43.2 27.4 35.6 18.1 20.2 12.6 11.8 62.2 29.0 29.5 ARHGAP26 "GRAF, KIAA0621, OPHN1L, OPHN1L1" ENSG00000145819 "Rho GTPase activating protein 26" Q9UNA1 5 142770377-143229011 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 237.3;Excitatory neurons: 611.6;Inhibitory neurons: 261.5;Late spermatids: 153.3;Microglial cells: 326.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "neutrophil: 24.7;NK-cell: 9.8" "Group enriched" "Detected in many" 4 "granulocytes: 24.7;NK-cells: 9.8" "Cell line enhanced" "Detected in many" "Karpas-707: 85.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035106, HPA035107" Enhanced Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA035106: AB_2674465, HPA035107: AB_10669855" "prognostic favorable (2.05e-4)" "prognostic favorable (1.36e-4)" "prognostic favorable (6.95e-4)" "prognostic favorable (5.93e-6)" "unprognostic (1.19e-1)" "unprognostic (1.93e-2)" "unprognostic (4.19e-3)" "unprognostic (5.93e-2)" "unprognostic (2.22e-1)" "unprognostic (9.43e-3)" "unprognostic (7.19e-3)" "unprognostic (8.65e-2)" "unprognostic (3.21e-3)" "unprognostic (5.67e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-2)" "prognostic favorable (2.88e-6)" 11.0 4.5 10.9 17.7 6.5 36.4 11.3 19.3 17.0 11.9 0.6 12.9 12.0 7.7 9.1 6.4 15.5 14.2 15.0 10.8 3.4 8.9 6.8 19.0 6.4 0.5 2.7 3.0 4.9 3.9 12.2 20.9 0.3 7.4 12.7 17.2 12.8 4.2 12.6 7.4 11.3 9.7 2.3 16.7 15.2 15.4 10.1 13.8 8.3 10.5 12.2 12.2 5.8 9.9 16.4 29.1 8.0 7.6 12.3 12.7 12.4 2.2 2.4 7.6 12.1 44.9 33.0 2.0 16.1 4.9 21.5 7.5 4.1 15.3 8.7 33.8 4.6 0.1 5.3 26.9 7.8 22.6 2.9 4.7 23.0 12.8 31.0 5.6 10.2 9.9 0.6 85.4 2.4 2.3 12.9 9.2 4.3 23.2 7.7 5.2 12.5 36.5 20.4 25.6 3.4 4.7 3.8 4.4 7.1 6.5 2.4 6.2 21.0 4.1 5.8 0.4 8.1 4.0 14.0 0.4 10.7 21.3 5.6 4.0 3.9 2.3 3.8 2.5 1.7 0.5 0.8 2.4 3.0 0.4 0.3 1.1 24.7 9.8 1.6 0.7 0.3 1.8 10.9 6.5 19.3 17.0 10.8 3.4 0.5 2.7 0.3 2.3 10.1 9.9 39.4 16.0 22.5 237.3 5.8 6.9 13.8 13.2 5.7 15.9 20.7 17.0 37.6 21.5 14.1 0.0 8.4 1.3 41.6 38.7 0.0 17.9 77.2 17.9 4.0 32.5 3.6 11.8 611.6 21.1 0.6 13.6 39.8 55.6 26.6 6.4 40.0 6.5 26.4 75.7 261.5 26.4 0.0 48.0 44.9 153.3 6.5 51.6 10.6 326.0 47.3 7.5 40.2 30.7 29.8 21.1 27.8 14.3 14.5 29.3 27.9 5.8 16.1 52.6 46.0 27.6 17.7 2.6 8.7 7.5 5.5 1.9 29.3 50.5 26.8 36.2 ARHGEF12 "KIAA0382, LARG" ENSG00000196914 "Rho guanine nucleotide exchange factor 12" Q9NZN5 11 120336413-120489937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018911, CAB025581" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "CAB025581: , HPA018911: AB_1845003" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (6.91e-3)" "unprognostic (1.28e-1)" "unprognostic (7.28e-2)" "unprognostic (5.39e-2)" "unprognostic (1.56e-1)" "unprognostic (5.55e-2)" "unprognostic (4.79e-2)" "unprognostic (7.77e-2)" "unprognostic (4.34e-3)" "unprognostic (4.78e-2)" "prognostic favorable (5.43e-6)" "unprognostic (1.29e-1)" "unprognostic (4.38e-2)" "unprognostic (2.13e-1)" "unprognostic (1.48e-1)" 25.6 30.6 27.2 14.3 26.9 11.4 31.9 26.8 32.1 32.9 26.4 27.6 25.0 27.8 25.4 27.6 29.3 28.4 40.3 30.9 23.0 67.4 66.4 36.7 11.9 17.8 25.6 25.2 26.1 68.4 14.6 42.9 17.3 26.5 29.1 47.7 25.0 30.9 32.2 49.5 25.5 30.3 20.1 21.5 32.2 9.7 35.9 13.5 51.5 31.8 18.7 28.7 22.0 19.3 38.1 31.6 41.9 39.8 55.0 54.5 16.7 43.8 49.8 26.1 33.1 37.5 27.2 3.2 51.7 79.8 46.6 27.5 54.1 56.0 51.3 31.1 25.8 61.8 34.0 29.2 49.2 0.1 43.7 52.4 39.7 57.8 63.8 58.0 80.7 32.7 52.4 122.5 67.0 26.6 0.1 0.1 11.4 49.3 26.1 13.4 47.4 11.9 65.1 66.1 30.0 36.4 61.5 51.0 16.2 25.0 43.1 5.1 80.1 57.2 24.2 37.6 32.4 35.1 15.4 20.2 23.6 7.9 44.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 27.2 26.9 26.8 32.1 30.9 23.0 17.8 25.6 17.3 20.1 35.9 19.3 86.2 73.7 88.4 274.9 8.6 90.5 69.1 47.2 42.1 134.6 55.1 26.9 87.6 68.6 57.8 97.5 185.6 16.7 11.5 59.7 35.2 45.6 6.4 61.4 55.7 94.0 37.8 69.7 239.0 50.9 10.4 44.0 34.7 140.3 11.4 44.9 85.6 118.3 7.3 90.9 192.4 39.6 18.3 31.2 25.6 14.8 29.8 18.2 51.6 118.0 8.7 41.0 13.4 143.2 55.0 53.5 52.1 33.4 9.3 85.6 48.1 76.3 48.7 80.9 26.3 58.4 60.3 16.3 13.8 55.3 85.1 28.7 16.1 43.1 41.3 99.1 ARL5A ARL5 ENSG00000162980 "ADP ribosylation factor like GTPase 5A" Q9Y689 2 151788984-151828492 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 88.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 88.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027002 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA027002: AB_10601685" "unprognostic (1.12e-2)" "unprognostic (2.17e-1)" "unprognostic (1.27e-1)" "unprognostic (9.36e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (1.28e-2)" "unprognostic (6.04e-2)" "unprognostic (4.59e-2)" "unprognostic (4.61e-3)" "unprognostic (2.47e-1)" "unprognostic (1.40e-1)" "unprognostic (2.95e-3)" "unprognostic (2.97e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-2)" "unprognostic (2.55e-1)" 20.4 20.9 13.1 13.1 14.9 11.8 19.7 17.1 12.4 14.7 12.1 17.6 22.1 14.1 7.3 23.9 14.6 17.2 35.8 12.8 18.5 25.1 22.4 20.0 20.3 18.5 14.7 15.3 15.9 17.9 7.5 23.6 17.3 17.2 16.6 17.6 15.5 13.6 32.5 28.8 20.5 18.0 17.7 14.6 17.7 6.3 14.4 17.5 29.6 36.5 24.6 18.3 11.2 18.8 20.2 20.2 29.0 25.7 20.9 35.6 39.1 34.7 26.8 24.8 30.0 59.5 24.7 66.9 36.4 37.2 18.6 12.8 34.6 26.7 40.0 40.4 31.6 73.6 21.9 77.8 28.8 74.0 39.5 27.9 39.3 34.0 36.4 33.3 34.7 41.1 55.7 78.0 26.5 23.4 63.1 29.3 36.8 24.7 21.5 28.5 40.1 27.6 35.7 33.6 13.0 27.0 21.1 21.8 29.5 34.3 17.0 44.0 28.5 19.6 24.1 18.8 37.7 39.3 47.6 64.6 34.7 50.4 34.7 88.3 7.9 8.9 6.9 6.1 6.5 11.0 6.1 8.6 11.2 15.2 6.6 5.1 3.8 7.4 4.7 6.7 7.9 4.5 13.1 14.9 17.1 12.4 12.8 18.5 18.5 14.7 17.3 17.7 14.4 18.8 18.1 57.7 38.6 28.7 104.3 138.7 122.6 120.7 64.3 62.6 24.4 12.6 109.8 91.5 60.6 14.7 14.6 84.3 46.2 44.3 45.0 55.3 11.9 15.3 17.2 62.9 75.6 66.3 29.8 59.9 153.1 79.6 51.5 12.1 48.2 17.9 77.8 76.6 128.0 116.1 31.9 64.3 126.1 135.8 154.7 13.8 74.6 82.9 81.8 51.5 97.5 64.1 132.8 34.7 23.8 52.6 44.1 82.4 160.7 167.4 166.8 42.9 60.3 61.9 72.3 85.9 60.4 72.6 65.0 103.9 163.7 143.0 63.6 9.2 72.7 135.9 ARR3 ARRX ENSG00000120500 "Arrestin 3" P36575 X 70268305-70281840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 170 "retina: 392.2" "Cell type enriched" "Detected in some" 8 "Cone photoreceptor cells: 1538.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA063129 Enhanced Approved "Golgi apparatus" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA063129: AB_2732696" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.70e-2)" "unprognostic (5.37e-2)" "unprognostic (2.82e-1)" "unprognostic (1.37e-2)" "unprognostic (2.06e-2)" "unprognostic (1.22e-1)" "unprognostic (1.35e-2)" "unprognostic (8.09e-2)" "unprognostic (1.33e-1)" "unprognostic (4.02e-3)" "unprognostic (2.77e-7)" "unprognostic (8.64e-2)" "unprognostic (6.53e-2)" "unprognostic (6.06e-2)" "unprognostic (1.43e-1)" 0.2 0.3 0.1 0.5 0.2 0.5 0.0 0.0 0.1 0.0 0.6 0.3 0.6 0.3 0.0 0.2 0.1 0.4 0.4 0.1 0.1 0.1 0.0 0.2 0.9 0.4 0.3 0.3 0.4 0.0 0.0 0.3 0.3 0.3 0.2 392.2 0.3 0.0 0.3 2.3 0.9 0.0 0.1 0.5 0.4 0.2 0.3 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.1 0.2 1.2 0.8 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.2 0.4 0.5 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.5 1.2 0.1 0.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.4 0.1 2.2 0.0 0.2 0.4 0.2 0.3 0.2 0.2 0.4 0.2 0.0 0.0 0.5 0.1 0.3 0.2 0.0 0.0 0.7 0.0 0.1 0.9 0.5 0.7 0.5 0.0 0.5 0.3 0.3 0.5 0.7 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.4 0.3 0.3 0.1 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 46.7 0.0 0.0 0.3 0.0 0.0 0.0 1538.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.2 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 68.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 172.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ARSA ENSG00000100299 "Arylsulfatase A" P15289 22 50622754-50628173 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 127.5;Plasma cells: 132.0;Proximal enterocytes: 93.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 80.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005554, CAB025183" Enhanced Uncertain "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 5600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" Cytosol "CAB025183: , HPA005554: AB_1078220" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (4.07e-2)" "prognostic favorable (2.96e-5)" "unprognostic (4.66e-2)" "unprognostic (4.40e-1)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.61e-2)" "unprognostic (2.16e-1)" "unprognostic (4.47e-2)" "unprognostic (2.76e-1)" "unprognostic (9.90e-2)" "unprognostic (1.41e-2)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (7.73e-3)" 28.8 25.1 14.4 15.6 18.0 18.4 27.2 16.8 21.8 21.3 27.5 31.3 30.8 22.4 8.6 28.1 25.1 15.7 33.0 14.9 15.2 31.4 42.8 29.1 19.8 20.0 15.9 11.3 46.7 11.7 34.7 10.9 19.1 28.9 8.2 4.4 39.6 16.2 25.3 17.5 33.8 6.5 16.3 44.5 30.3 54.0 19.4 9.8 32.3 5.1 9.5 23.9 24.7 21.0 8.5 11.0 5.3 10.9 41.8 21.8 13.5 13.0 15.9 5.7 9.3 3.3 12.9 5.3 8.2 22.9 10.8 12.8 1.2 12.3 1.0 2.7 8.0 3.4 14.3 12.5 28.3 5.2 32.7 26.0 24.4 9.5 6.3 19.9 12.8 11.5 3.5 80.4 12.1 9.6 4.6 5.8 1.7 9.0 11.2 4.0 0.4 26.7 9.9 13.5 2.5 8.2 18.2 17.2 10.1 5.1 7.7 6.6 22.1 3.8 15.1 14.9 4.1 18.4 1.9 4.5 11.7 4.3 13.6 10.4 27.7 36.1 17.3 33.3 15.1 10.4 12.4 14.2 22.7 12.5 7.3 10.0 60.4 8.9 43.2 32.1 18.2 16.3 14.4 18.0 16.8 21.8 14.9 15.2 20.0 15.9 19.1 16.3 19.4 21.0 22.8 6.4 12.9 24.5 22.2 4.7 14.0 23.8 18.8 5.3 18.9 13.1 8.0 27.1 15.5 12.9 4.2 11.5 14.0 85.4 1.9 29.4 62.4 24.4 10.3 13.4 36.7 9.7 9.4 21.3 19.9 19.6 41.3 21.3 6.3 15.3 8.2 28.6 36.8 6.7 8.6 30.6 14.2 29.0 9.5 127.5 10.8 29.2 17.8 10.3 28.7 10.3 8.2 8.0 11.9 24.2 75.2 6.0 132.0 10.8 93.9 22.7 21.2 7.2 0.0 6.6 9.9 48.3 4.1 18.3 5.5 13.3 17.2 7.2 25.0 16.1 ASPHD2 FLJ39838 ENSG00000128203 "Aspartate beta-hydroxylase domain containing 2" Q6ICH7 22 26429260-26445015 "Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;skin 1: 11.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.8;Early spermatids: 25.3;Late spermatids: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.3" "Group enriched" "Detected in many" 4 "dendritic cells: 2.4;monocytes: 5.3" "Cell line enhanced" "Detected in many" "Karpas-707: 21.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000820 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "HPA000820: AB_1078231" "unprognostic (1.12e-1)" "unprognostic (1.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.71e-1)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "unprognostic (2.02e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-2)" "unprognostic (8.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.06e-5)" "unprognostic (6.55e-2)" "unprognostic (9.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.11e-2)" 0.7 0.6 8.0 2.5 16.9 1.5 0.6 10.4 9.0 1.5 0.6 2.0 1.2 1.2 6.2 1.5 0.5 1.1 0.4 8.3 7.0 6.1 0.3 0.9 4.4 4.1 4.3 0.6 0.5 1.7 6.6 1.1 5.5 1.1 2.0 5.6 1.0 0.7 0.4 11.1 1.6 0.7 3.1 2.8 8.2 1.9 6.4 1.3 2.0 0.1 3.3 2.3 1.1 5.8 1.6 0.9 4.1 6.5 0.6 0.3 2.2 2.1 4.5 4.3 6.2 0.0 0.4 1.4 0.5 2.0 4.3 1.9 4.5 7.2 2.3 9.7 6.1 0.3 0.0 0.3 4.1 2.4 1.1 0.7 3.4 2.2 3.0 4.7 4.6 3.6 1.7 21.9 1.3 0.4 1.8 1.0 4.0 8.5 0.9 12.2 2.3 3.7 6.0 0.6 11.0 4.8 2.1 0.3 2.4 2.2 0.2 3.5 4.3 2.7 13.4 0.6 4.4 6.3 1.7 2.8 4.1 8.6 1.8 0.0 1.2 0.5 0.3 3.3 0.9 0.9 0.7 0.7 2.1 0.9 0.4 0.4 0.3 0.0 5.3 2.4 0.4 0.4 8.0 16.9 10.4 9.0 8.3 7.0 4.1 4.3 5.5 3.1 6.4 5.8 0.3 0.0 1.1 4.2 5.1 1.8 1.4 2.1 0.0 24.8 0.9 0.9 0.6 1.5 0.9 0.0 10.4 0.3 6.8 3.3 0.0 1.2 25.3 0.7 0.5 1.1 0.0 0.0 14.1 0.7 13.2 1.3 8.2 1.5 0.0 0.9 1.1 0.1 1.5 6.7 9.7 4.3 2.0 2.8 5.7 25.1 0.9 4.1 1.8 1.0 5.3 2.4 2.1 4.5 1.1 5.9 0.8 0.7 12.1 4.6 0.1 0.7 0.8 11.3 0.0 0.4 0.7 1.1 3.3 0.6 1.1 1.1 2.8 0.4 2.0 4.2 ATP23 "KUB3, XRCC6BP1" ENSG00000166896 "ATP23 metallopeptidase and ATP synthase assembly factor homolog" Q9Y6H3 12 57906039-57959148 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 12.7;Cytotrophoblasts: 14.4;Distal tubular cells: 17.6;Extravillous trophoblasts: 15.2;Proximal tubular cells: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Cell line enhanced" "Detected in some" "A549: 1.0;Karpas-707: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035804, HPA043204" Uncertain Enhanced "Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "Cell Junctions, Cytosol" "HPA035804: AB_10601026, HPA043204: AB_2678361" "unprognostic (2.56e-1)" "unprognostic (1.31e-2)" "unprognostic (8.82e-2)" "unprognostic (2.92e-2)" "unprognostic (2.30e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (5.28e-2)" "unprognostic (5.41e-3)" "unprognostic (1.03e-2)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (4.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-1)" 7.5 4.9 0.6 0.4 0.5 0.1 5.6 0.6 0.9 4.1 0.5 8.1 0.2 3.1 0.0 5.6 3.2 0.0 4.6 1.0 0.3 4.0 5.2 2.6 0.1 0.4 0.2 3.1 5.9 0.0 2.8 0.1 0.4 3.3 0.0 0.5 3.6 0.0 12.4 4.4 4.3 0.0 0.3 3.2 4.2 27.8 0.5 0.0 3.5 0.0 0.1 4.7 4.0 0.3 0.6 1.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.9 0.2 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.6 2.6 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.8 0.1 0.0 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.0 0.4 0.0 0.0 0.4 0.0 0.6 0.1 0.2 0.0 0.2 0.2 0.2 0.2 0.1 0.3 0.0 0.3 0.2 0.2 1.6 0.1 0.1 0.1 0.1 0.0 0.6 0.5 0.6 0.9 1.0 0.3 0.4 0.2 0.4 0.3 0.5 0.3 8.0 0.0 9.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 7.4 12.7 0.0 0.0 1.8 3.7 0.0 14.4 4.2 0.0 17.6 6.1 0.0 5.6 4.9 2.8 0.0 0.0 0.0 10.7 15.2 2.3 0.0 6.0 11.4 6.8 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.9 0.0 0.0 26.1 0.7 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 3.0 9.5 0.0 0.0 ATP6V0A1 "a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1" ENSG00000033627 "ATPase H+ transporting V0 subunit a1" Q93050 17 42458844-42522582 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 130.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 294.0;Rod photoreceptor cells: 403.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022144 Enhanced Approved "Nuclear speckles,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "Nuclear speckles, Cytosol" "HPA022144: AB_1845189" "unprognostic (3.93e-2)" "unprognostic (2.02e-1)" "unprognostic (4.35e-2)" "unprognostic (2.22e-2)" "unprognostic (1.60e-2)" "unprognostic (8.69e-2)" "unprognostic (1.84e-2)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.85e-1)" "prognostic favorable (2.05e-4)" "unprognostic (3.25e-1)" "prognostic favorable (1.28e-4)" "unprognostic (3.07e-1)" "unprognostic (3.68e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (6.90e-4)" 17.7 28.2 30.6 18.0 35.2 21.5 16.3 16.8 42.7 13.4 0.0 22.1 34.6 20.9 19.6 17.4 17.1 22.7 18.9 43.6 44.1 37.4 21.0 24.1 13.1 25.6 26.2 20.0 17.4 86.0 39.0 21.2 34.6 17.4 20.5 130.7 13.5 18.6 59.3 28.1 24.3 21.5 12.1 21.8 16.3 18.7 30.9 15.2 30.3 25.3 14.9 11.9 12.8 27.2 18.4 37.0 22.1 40.1 36.5 31.7 12.9 12.7 23.3 26.4 34.2 23.9 39.9 3.4 22.6 26.2 36.2 38.7 34.5 21.5 30.4 28.3 36.2 29.2 27.3 19.0 22.7 12.8 50.9 23.5 30.3 42.4 18.0 32.6 18.9 13.2 108.0 111.3 39.7 15.8 5.1 11.3 14.3 23.9 0.4 0.2 23.0 51.2 30.2 14.4 60.9 32.0 19.7 17.7 37.1 28.8 43.0 19.0 11.4 22.3 0.9 33.0 15.3 45.0 66.1 6.8 29.7 0.2 26.5 21.6 14.5 11.2 1.0 4.4 1.6 4.7 0.7 0.2 12.2 7.3 1.2 0.9 18.7 0.1 3.3 6.2 3.7 6.6 30.6 35.2 16.8 42.7 43.6 44.1 25.6 26.2 34.6 12.1 30.9 27.2 20.0 19.2 48.0 47.0 23.0 19.8 56.7 15.7 32.5 164.8 15.7 16.5 21.1 28.6 18.3 14.7 294.0 34.3 16.7 46.2 11.7 16.3 4.0 32.8 27.4 22.2 84.9 45.8 125.0 18.5 15.7 31.0 23.4 74.0 24.1 74.5 16.4 37.8 53.8 95.9 112.3 27.3 12.2 37.8 29.2 3.9 17.4 42.8 40.9 38.4 17.7 59.3 3.1 61.3 80.5 24.2 37.6 23.7 13.8 32.7 56.9 32.5 11.4 403.4 6.6 39.4 32.3 38.8 18.2 21.7 20.2 99.9 6.9 35.0 24.5 14.9 ATP7A MNK ENSG00000165240 "ATPase copper transporting alpha" Q04656 X 77910656-78050395 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ionocytes: 61.1;Microglial cells: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012887, HPA048107" Approved Supported "Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA012887: AB_1845205, HPA048107: AB_2680266" "unprognostic (3.14e-2)" "unprognostic (3.48e-1)" "unprognostic (4.90e-2)" "unprognostic (1.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-3)" "unprognostic (2.59e-2)" "unprognostic (3.17e-2)" "unprognostic (2.47e-1)" "unprognostic (2.30e-2)" "unprognostic (1.14e-1)" "prognostic favorable (8.38e-4)" "unprognostic (1.06e-1)" "unprognostic (2.16e-1)" "unprognostic (3.69e-1)" "unprognostic (2.52e-1)" 3.0 4.3 1.2 3.6 1.7 5.9 6.3 2.3 2.1 3.9 1.6 3.4 3.9 3.6 5.0 4.9 3.5 3.6 2.5 1.3 2.1 4.4 2.3 4.5 4.1 2.1 2.1 3.6 2.4 7.3 2.5 4.0 3.8 5.3 3.4 3.0 5.1 3.4 1.8 11.1 3.4 3.2 1.1 4.7 5.5 1.6 1.6 4.7 4.6 2.9 4.6 3.9 2.8 2.9 3.2 8.3 5.4 5.5 5.0 5.3 0.9 4.8 6.6 2.8 5.7 1.0 3.6 4.7 6.9 4.8 3.3 3.8 7.1 3.9 5.2 7.0 4.8 2.4 7.8 0.8 6.3 4.1 4.1 5.6 1.6 5.9 1.8 6.5 7.3 4.7 19.6 17.4 5.2 2.8 4.6 1.4 1.5 11.2 1.7 3.7 9.0 15.8 4.6 8.8 1.6 20.4 11.9 2.8 6.0 3.3 2.2 1.3 9.4 3.7 3.6 5.2 1.9 5.6 10.7 5.2 6.0 2.5 5.7 7.1 1.5 4.5 1.8 1.5 0.9 1.8 1.2 1.2 1.0 1.4 1.4 2.1 8.1 1.2 1.9 1.0 0.4 1.0 1.2 1.7 2.3 2.1 1.3 2.1 2.1 2.1 3.8 1.1 1.6 2.9 14.3 0.0 8.4 15.7 12.6 7.4 5.1 5.8 13.1 6.4 17.3 10.0 5.1 1.5 8.2 9.2 4.2 2.0 15.0 4.5 1.9 5.6 0.5 5.3 9.2 9.7 4.8 22.5 11.1 13.6 2.2 9.4 20.4 8.8 9.5 6.4 14.6 3.6 14.3 1.7 12.5 4.8 61.1 11.7 6.7 1.1 7.2 12.6 19.6 44.0 5.5 4.4 11.3 37.7 35.0 6.2 4.1 9.8 10.5 4.8 4.1 5.5 10.2 4.1 32.9 10.3 8.7 1.8 5.4 20.5 16.6 2.2 13.8 6.7 5.2 6.6 ATP8B3 ATPIK ENSG00000130270 "ATPase phospholipid transporting 8B3" O60423 19 1782075-1812276 "Enzymes, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 5.9;testis: 21.9" "Cell type enhanced" "Detected in many" "Early spermatids: 9.5;Late spermatids: 11.7;Spermatocytes: 20.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 12.5;Karpas-707: 22.4;U-266/70: 18.5" "Low region specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (6.50e-2)" "unprognostic (1.81e-2)" "unprognostic (1.02e-1)" "unprognostic (6.05e-5)" "unprognostic (6.66e-2)" "unprognostic (7.91e-2)" "unprognostic (1.86e-2)" "unprognostic (2.66e-2)" "unprognostic (2.42e-1)" "unprognostic (2.55e-3)" "unprognostic (1.28e-2)" "unprognostic (6.15e-3)" "prognostic unfavorable (4.80e-9)" "unprognostic (8.05e-2)" "unprognostic (3.20e-1)" "unprognostic (3.19e-2)" "unprognostic (1.19e-1)" 0.5 1.9 0.4 0.6 0.3 5.9 0.4 0.3 0.4 0.6 0.3 0.3 0.3 1.2 0.3 0.4 0.4 0.2 0.2 0.3 0.4 0.2 0.6 0.5 0.7 0.4 0.3 0.5 0.2 0.1 0.3 0.3 0.5 0.3 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.8 0.4 3.3 0.2 21.9 0.5 2.3 0.5 0.3 0.8 0.4 0.6 0.3 0.8 6.3 0.7 0.9 0.7 0.6 0.0 2.5 3.7 2.4 2.2 0.1 2.5 2.7 2.7 1.9 0.3 0.2 0.5 0.1 1.1 2.7 0.1 0.8 3.2 1.2 0.2 1.7 12.5 0.3 0.2 0.0 2.5 3.7 0.6 8.0 2.1 22.4 4.0 0.3 1.7 5.0 0.2 0.3 2.9 2.7 0.5 0.3 3.4 0.1 0.0 0.8 0.7 0.0 0.4 0.6 0.7 8.0 5.9 0.1 4.7 0.9 2.6 18.5 9.8 0.7 4.7 8.0 3.1 0.0 0.9 0.8 0.8 3.1 0.3 0.0 0.5 0.5 0.5 0.0 0.2 0.7 0.3 1.1 0.9 0.2 1.3 0.6 0.4 0.3 0.3 0.4 0.3 0.4 0.4 0.3 0.5 0.4 0.5 0.3 1.5 0.0 0.6 1.0 0.5 0.8 0.5 0.9 4.6 2.4 1.0 1.8 1.6 4.3 0.3 0.0 2.1 0.1 1.2 0.1 0.0 1.0 9.5 3.9 1.8 2.1 0.0 0.8 0.6 0.2 1.2 2.0 0.5 5.1 1.3 3.9 4.6 0.8 1.4 0.0 0.5 0.1 0.0 4.1 1.9 11.7 0.3 2.0 1.8 1.0 1.1 0.7 2.1 0.5 0.2 0.2 0.0 0.4 0.9 0.3 0.5 0.1 0.2 0.7 0.0 0.3 0.7 20.9 3.7 2.5 1.4 0.4 2.7 4.2 0.1 0.2 ATP9B ATPIIB ENSG00000166377 "ATPase phospholipid transporting 9B (putative)" O43861 18 79069285-79378287 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 128.2;Alveolar cells type 2: 156.2;Excitatory neurons: 126.0;Inhibitory neurons: 115.0;Oligodendrocyte precursor cells: 114.6;Oligodendrocytes: 157.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029364 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA029364: AB_10602595" "unprognostic (2.84e-3)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (6.51e-3)" "unprognostic (7.32e-2)" "unprognostic (7.66e-4)" "unprognostic (2.45e-2)" "unprognostic (7.43e-2)" "unprognostic (2.55e-2)" "unprognostic (8.21e-2)" "unprognostic (1.61e-1)" "unprognostic (2.93e-1)" "unprognostic (1.92e-3)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.05e-2)" "unprognostic (1.09e-2)" 8.7 8.1 11.3 8.4 17.7 30.6 9.1 31.9 24.9 8.3 10.9 8.6 6.2 11.1 9.9 9.7 9.2 8.5 7.2 15.2 9.6 10.9 16.2 10.3 9.3 6.0 3.7 14.1 9.2 15.2 4.8 9.6 7.5 10.8 9.7 22.6 10.3 8.1 10.4 11.8 7.6 8.0 2.6 8.8 10.3 19.1 6.6 9.3 12.4 5.8 7.2 7.6 5.5 35.1 25.0 11.7 15.9 17.5 7.9 13.4 12.3 12.1 7.9 6.9 5.8 12.3 15.9 12.5 20.4 8.7 6.5 10.1 13.0 6.7 11.2 19.6 5.6 14.8 13.7 9.0 10.6 27.1 15.1 10.7 8.3 11.1 6.9 10.3 9.7 15.0 14.3 31.7 9.7 20.0 17.5 10.5 23.3 14.5 14.1 16.8 13.2 17.3 9.7 19.6 11.7 12.5 13.3 14.6 8.4 27.2 16.8 15.9 17.4 14.6 24.2 6.6 8.0 16.0 27.5 27.8 8.7 17.6 15.5 11.7 8.7 7.1 6.0 7.5 6.9 6.6 6.7 5.9 6.3 7.0 8.5 6.5 9.8 6.8 13.6 6.0 6.0 5.7 11.3 17.7 31.9 24.9 15.2 9.6 6.0 3.7 7.5 2.6 6.6 35.1 14.3 128.2 156.2 91.1 19.6 5.7 8.5 5.4 14.8 35.7 9.6 8.8 10.1 14.3 55.6 9.2 41.7 7.0 20.6 8.4 1.9 6.1 26.7 8.4 20.5 17.6 12.0 5.5 126.0 5.6 3.9 19.2 30.1 11.8 43.6 21.5 11.4 7.7 14.1 42.1 115.0 8.6 2.0 15.7 9.9 45.3 15.8 25.7 7.2 85.3 11.4 13.2 14.4 114.6 157.2 7.9 10.2 11.3 20.3 6.1 5.9 4.0 95.6 38.1 6.6 17.8 13.0 40.1 25.0 9.3 7.2 7.7 27.3 18.0 10.1 8.0 ATXN7 "ADCAII, OPCA3, SCA7, SGF73" ENSG00000163635 "Ataxin 7" O15265 3 63863155-64003462 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 102.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 15.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034989 Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA034989: AB_10602596" "unprognostic (1.51e-2)" "unprognostic (2.44e-1)" "unprognostic (5.98e-2)" "unprognostic (2.18e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.22e-4)" "unprognostic (9.65e-2)" "unprognostic (2.76e-2)" "unprognostic (2.46e-1)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "unprognostic (9.77e-3)" "unprognostic (2.56e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "unprognostic (3.45e-2)" 7.5 6.3 4.5 11.4 4.1 24.4 7.1 4.9 4.4 7.4 0.2 6.9 8.0 8.6 4.7 8.7 6.3 9.6 5.8 3.1 3.7 7.1 8.4 9.0 12.7 3.4 3.3 8.0 21.0 10.9 2.3 8.3 2.7 6.7 8.8 16.3 7.8 5.2 7.1 9.3 9.2 7.9 0.7 10.6 8.4 15.0 3.1 16.5 7.5 8.7 11.7 7.4 4.4 3.2 8.4 5.7 8.1 7.2 8.5 11.3 9.5 6.5 9.0 11.1 10.5 8.9 8.7 12.5 3.1 9.0 12.5 6.5 9.6 9.1 11.9 22.8 4.9 16.1 10.7 4.2 6.4 8.5 17.7 7.9 9.0 15.7 17.7 9.0 8.4 13.3 6.3 26.2 7.7 25.8 12.7 6.8 5.5 5.7 3.0 9.1 7.1 10.1 6.1 11.0 3.1 5.6 13.2 9.4 10.8 6.4 5.1 12.2 11.9 11.4 12.0 12.7 12.9 12.9 13.2 10.3 10.3 11.6 9.4 15.8 1.1 2.1 3.7 1.0 3.3 1.0 6.2 4.0 0.8 2.4 6.2 4.1 4.5 3.5 0.7 1.5 6.2 1.3 4.5 4.1 4.9 4.4 3.1 3.7 3.4 3.3 2.7 0.7 3.1 3.2 2.4 9.6 9.1 34.6 17.0 43.6 24.9 17.6 29.6 73.2 3.4 1.7 10.5 35.8 17.9 5.5 102.2 14.1 21.5 38.3 0.0 2.8 17.1 3.3 1.5 16.1 26.4 29.5 81.2 4.2 13.6 16.6 18.8 3.5 14.7 1.2 26.7 22.8 14.2 25.2 67.0 19.7 24.4 34.6 30.3 9.5 12.8 20.1 12.4 64.6 33.5 24.5 54.6 60.3 46.7 2.5 28.5 13.2 14.8 26.1 28.1 0.7 27.4 70.8 0.0 39.2 15.6 14.8 15.6 25.6 46.2 61.2 41.5 1.6 20.1 38.6 AVPR1A AVPR1 ENSG00000166148 "Arginine vasopressin receptor 1A" P37288 12 63142759-63151201 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 56.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 24.1;Hepatocytes: 62.7;Sertoli cells: 78.9;Smooth muscle cells: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "ASC diff: 5.6;Karpas-707: 13.1;U-266/84: 9.8" "Group enriched" "Detected in some" 5 "basal ganglia: 7.0;hypothalamus: 3.8" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (1.49e-1)" "unprognostic (2.82e-1)" "unprognostic (9.90e-3)" "unprognostic (2.90e-1)" "unprognostic (1.59e-1)" "unprognostic (1.43e-3)" "unprognostic (3.79e-2)" "unprognostic (2.60e-1)" "unprognostic (3.58e-6)" "unprognostic (1.45e-1)" "unprognostic (7.29e-2)" "unprognostic (1.55e-1)" "unprognostic (1.38e-3)" "unprognostic (4.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.77e-2)" "unprognostic (4.66e-4)" 17.2 56.6 0.4 1.4 0.2 0.0 9.0 0.0 0.3 9.1 1.4 1.7 0.7 10.9 1.1 3.0 4.8 6.1 2.0 0.3 0.5 4.6 20.9 0.5 1.2 0.5 0.2 1.3 2.3 2.2 0.5 0.3 0.2 2.3 1.2 1.4 1.1 4.2 2.0 1.8 0.9 12.2 0.1 0.8 1.7 0.6 0.8 1.4 10.4 3.5 0.6 2.5 2.6 0.2 0.1 0.2 0.6 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.3 0.3 0.5 0.5 0.2 0.2 0.1 0.8 0.2 14.1 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.6 0.3 0.2 0.3 3.4 1.5 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.4 3.1 24.1 4.5 0.0 2.7 0.1 0.0 0.5 2.7 0.5 1.6 0.0 0.2 0.7 62.7 0.2 0.0 1.0 0.0 0.0 1.3 0.3 0.0 2.8 1.4 0.0 0.0 0.0 7.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 78.9 2.9 100.9 0.2 0.2 0.0 0.3 0.1 0.6 2.1 0.0 0.3 BACH1 "BACH-1, BTBD24" ENSG00000156273 "BTB domain and CNC homolog 1" O14867 21 29194071-29630751 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.4" "Cell type enhanced" "Detected in all" "Early spermatids: 164.4;Late spermatids: 422.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 150.2" "Group enriched" "Detected in all" 4 "granulocytes: 150.2;monocytes: 51.1" "Cell line enhanced" "Detected in all" "Karpas-707: 129.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034949 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA034949: AB_2674376" "unprognostic (1.57e-1)" "unprognostic (8.08e-3)" "unprognostic (2.64e-1)" "unprognostic (2.33e-2)" "unprognostic (6.00e-2)" "unprognostic (2.99e-1)" "unprognostic (9.84e-3)" "unprognostic (1.20e-3)" "unprognostic (5.76e-2)" "unprognostic (5.79e-3)" "prognostic unfavorable (3.11e-5)" "unprognostic (5.63e-2)" "prognostic unfavorable (7.14e-4)" "unprognostic (2.59e-1)" "unprognostic (1.60e-1)" "unprognostic (4.19e-2)" "unprognostic (8.70e-2)" 15.8 12.1 12.3 27.8 13.3 89.4 13.3 27.6 16.0 18.1 9.9 13.4 17.4 19.8 9.7 23.0 9.1 26.1 13.2 10.5 19.5 16.0 30.5 21.4 16.9 23.0 28.4 11.6 17.2 8.3 3.3 50.6 31.0 13.3 13.2 12.0 17.4 8.6 26.3 23.3 17.4 15.9 14.2 20.7 13.5 27.3 16.6 14.2 12.6 12.8 14.8 29.8 13.1 12.3 21.5 8.6 26.1 6.8 20.2 57.7 16.3 23.0 55.0 21.8 24.3 18.1 28.9 25.5 18.0 21.1 22.7 11.1 15.7 30.9 38.6 21.3 13.3 78.7 18.9 18.6 26.8 22.8 28.1 30.3 46.4 42.8 63.4 25.7 11.7 13.9 40.6 129.7 30.2 7.6 19.5 13.0 40.3 8.4 8.9 19.8 61.8 33.1 11.5 16.8 10.8 12.2 12.6 23.5 29.0 26.0 17.1 27.1 29.6 21.3 29.4 23.1 11.8 74.9 51.9 26.9 17.3 27.8 64.9 72.4 51.1 38.6 5.0 40.1 4.1 10.3 8.3 4.3 24.9 13.7 11.9 6.0 150.2 7.1 46.0 6.0 14.8 15.3 12.3 13.3 27.6 16.0 10.5 19.5 23.0 28.4 31.0 14.2 16.6 12.3 31.9 28.9 15.3 12.1 90.6 59.0 53.2 17.9 19.4 16.6 18.3 15.1 20.7 15.7 23.1 14.7 18.8 13.7 33.0 30.7 7.9 19.8 164.4 32.2 45.9 26.0 30.9 33.0 5.1 16.6 15.7 31.3 30.5 64.1 48.6 13.6 22.1 20.9 22.0 13.5 36.9 24.7 12.2 57.1 113.8 422.4 13.4 113.8 21.4 68.4 109.1 10.2 24.7 33.7 25.0 28.2 38.2 14.3 87.8 50.7 25.5 12.8 15.7 12.6 32.9 54.7 36.6 31.5 28.4 34.7 58.1 39.7 31.3 17.4 11.7 48.4 BAZ2A "KIAA0314, TIP5, WALp3" ENSG00000076108 "Bromodomain adjacent to zinc finger domain 2A" Q9UIF9 12 56595596-56636816 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005782, HPA063806" Enhanced "Nuclear speckles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA005782: AB_10601089, HPA063806: AB_2685128" "unprognostic (1.70e-1)" "unprognostic (1.75e-2)" "unprognostic (5.76e-2)" "unprognostic (1.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (3.72e-2)" "unprognostic (3.10e-1)" "unprognostic (6.45e-2)" "unprognostic (9.64e-2)" "unprognostic (3.00e-2)" "unprognostic (3.77e-2)" "unprognostic (1.73e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-2)" "unprognostic (3.43e-1)" 29.1 23.9 10.3 30.8 13.3 65.9 27.2 22.9 18.7 29.3 19.1 27.0 25.5 25.4 22.9 30.9 24.9 20.9 21.1 10.3 20.0 19.8 21.7 35.9 33.4 17.2 13.0 36.3 30.8 33.4 27.7 35.4 14.6 23.3 26.6 48.8 25.7 21.0 28.2 29.9 31.1 23.1 5.5 35.3 26.2 47.4 19.0 50.6 27.3 32.0 30.6 24.8 30.6 19.8 50.3 45.6 61.9 52.5 35.3 35.4 66.5 32.6 44.2 46.9 34.1 56.2 59.3 69.2 49.2 38.6 44.3 41.5 70.6 46.3 40.6 48.1 37.1 80.8 35.5 28.8 38.5 47.1 60.2 31.0 43.8 40.2 55.7 50.8 46.3 28.4 87.7 94.1 26.3 30.7 40.2 30.9 54.9 32.7 34.6 33.9 45.0 48.3 32.6 48.8 41.0 33.8 54.8 57.0 30.0 66.0 65.6 41.7 65.2 24.3 49.1 30.0 23.0 46.0 48.4 65.1 22.5 33.4 34.6 12.1 7.6 5.6 4.8 6.2 4.2 6.8 3.8 3.7 3.0 6.0 3.1 2.7 28.6 17.2 15.5 11.7 3.6 3.0 10.3 13.3 22.9 18.7 10.3 20.0 17.2 13.0 14.6 5.5 19.0 19.8 47.6 67.3 61.3 29.4 74.7 50.9 43.2 35.3 60.3 70.5 43.3 26.7 26.4 30.0 36.9 25.8 137.6 48.0 62.8 71.6 7.9 32.0 66.8 29.4 33.7 50.1 44.8 53.4 29.3 28.7 37.2 35.6 34.1 41.7 43.6 34.8 53.9 32.5 24.3 32.0 27.4 39.6 26.4 62.1 65.6 73.7 60.6 38.5 39.2 40.3 80.1 24.4 116.4 25.6 33.2 34.8 39.4 57.6 78.0 65.1 44.7 12.6 34.4 67.3 85.5 44.9 44.0 134.1 131.2 59.5 61.8 95.6 58.0 41.6 34.8 67.6 BCHE "CHE1, CHE2, E1" ENSG00000114200 Butyrylcholinesterase P06276 3 165772904-165837462 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 525.1" "Group enriched" "Detected in many" 9 "Hepatocytes: 420.3;Oligodendrocyte precursor cells: 210.1" "Group enriched" "Detected in many" 6 "glioma: 24.0;liver cancer: 13.7;melanoma: 18.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "Karpas-707: 785.6" "Low region specificity" "Detected in all" HPA001560 Approved "Secreted to blood" NA NA 9400000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "HPA001560: AB_1078271" "unprognostic (4.74e-2)" "unprognostic (2.00e-1)" "unprognostic (9.21e-4)" "unprognostic (8.19e-8)" "unprognostic (2.66e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.44e-1)" "unprognostic (5.04e-2)" "unprognostic (6.15e-2)" "unprognostic (9.59e-2)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" "unprognostic (3.18e-3)" "unprognostic (4.46e-5)" "unprognostic (2.17e-2)" "unprognostic (5.92e-2)" "unprognostic (4.26e-4)" 30.4 11.6 9.3 2.7 7.4 0.0 4.7 7.5 12.0 22.0 5.0 36.1 4.7 41.0 24.3 25.8 36.2 6.0 9.7 7.9 7.3 4.9 525.1 10.9 0.2 7.9 9.4 3.7 2.3 0.1 1.8 0.0 7.8 12.5 16.1 8.8 1.9 32.3 2.7 8.7 10.6 29.7 7.4 5.9 3.5 1.3 12.2 2.9 1.3 5.1 0.1 11.3 5.1 9.4 0.0 2.1 82.1 0.1 0.2 0.0 0.1 0.0 1.5 0.6 7.3 0.0 0.1 0.3 30.7 0.0 0.0 0.5 5.7 0.4 5.8 0.4 0.8 0.0 0.0 0.0 6.3 0.2 0.4 23.5 1.4 0.0 8.1 25.3 3.6 30.0 0.0 785.6 0.0 0.0 0.0 0.1 2.1 0.0 0.8 0.0 28.4 67.3 0.7 0.0 0.0 0.8 0.1 0.0 46.5 0.0 34.0 0.2 0.0 19.3 0.5 0.0 8.3 3.5 0.0 1.6 8.2 0.2 84.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 7.4 7.5 12.0 7.9 7.3 7.9 9.4 7.8 7.4 12.2 9.4 5.8 0.0 0.0 1.0 0.7 5.5 0.9 0.0 1.8 1.4 0.0 0.1 9.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.6 0.0 0.7 3.4 0.0 8.0 3.0 0.0 0.0 22.0 0.5 0.0 0.0 0.2 8.9 420.3 0.1 1.7 10.5 0.4 0.0 4.7 1.5 8.7 2.1 0.3 19.6 3.7 0.0 31.7 0.0 210.1 16.1 0.0 0.0 0.0 0.0 0.2 0.0 3.7 0.0 1.2 0.0 0.8 6.5 0.3 0.3 0.6 3.4 0.0 1.1 0.1 0.0 0.1 BCLAF3 CXorf23 ENSG00000173681 "BCLAF1 and THRAP3 family member 3" A2AJT9 X 19912860-19970298 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Alveolar cells type 2: 17.0;Granulosa cells: 12.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027215 Approved Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA027215: AB_1847358" "unprognostic (2.46e-1)" "unprognostic (1.96e-1)" "unprognostic (3.15e-1)" "unprognostic (2.24e-1)" "unprognostic (2.27e-2)" "unprognostic (2.48e-2)" "unprognostic (3.72e-2)" "prognostic favorable (5.42e-4)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (1.43e-1)" "unprognostic (4.83e-2)" "unprognostic (2.03e-2)" "unprognostic (2.21e-1)" "unprognostic (9.38e-2)" "unprognostic (2.30e-2)" "prognostic favorable (5.56e-4)" 4.6 3.0 3.5 3.8 4.0 3.6 5.2 10.2 3.8 4.7 2.0 5.2 3.4 5.5 8.3 3.5 4.0 4.2 3.4 4.0 3.1 4.3 2.7 4.5 4.3 3.4 3.4 5.0 3.4 5.7 3.4 3.3 3.6 5.0 5.9 6.4 3.4 5.1 4.5 6.0 4.4 4.0 2.6 4.1 3.9 2.6 5.0 5.3 4.7 5.2 4.2 4.2 4.1 5.0 4.8 3.8 5.1 8.7 4.5 6.3 2.8 4.4 3.7 2.8 3.9 3.4 5.0 4.9 2.6 5.2 4.9 3.5 4.6 3.3 5.3 3.2 3.7 3.1 4.3 3.4 6.3 4.4 5.3 5.7 5.0 3.1 4.2 6.5 3.2 3.9 2.3 11.5 3.2 3.6 3.1 2.9 4.5 4.5 4.8 1.3 5.1 6.7 7.3 4.7 3.1 4.8 5.6 4.6 4.5 9.5 5.5 3.9 6.0 4.7 2.3 11.4 3.3 3.6 3.0 4.0 4.0 2.4 4.1 1.8 0.3 0.6 0.4 0.4 0.5 0.4 0.3 0.4 0.2 0.8 0.3 0.4 1.5 0.4 0.4 0.7 0.2 0.1 3.5 4.0 10.2 3.8 4.0 3.1 3.4 3.4 3.6 2.6 5.0 5.0 10.8 16.0 17.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 8.8 8.1 0.0 0.0 7.4 9.2 0.0 4.5 8.9 0.0 1.9 6.1 0.0 8.2 9.4 3.4 0.0 0.0 0.0 3.6 3.5 5.0 0.0 10.9 6.3 12.2 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 6.1 0.0 0.0 3.6 0.0 0.0 6.2 4.4 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 4.5 3.9 7.4 0.0 0.0 BEX5 NGFRAP1L1 ENSG00000184515 "Brain expressed X-linked 5" Q5H9J7 X 102153708-102155977 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 124.0;pituitary gland: 77.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 171.6;Distal tubular cells: 137.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 45.7;thyroid cancer: 14.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 6.2;MAIT T-cell: 15.5;memory CD4 T-cell: 11.6;memory CD8 T-cell: 8.1;naive CD4 T-cell: 16.4;naive CD8 T-cell: 10.1;NK-cell: 10.1;T-reg: 11.9" "Group enriched" "Detected in many" 6 "NK-cells: 10.1;T-cells: 16.4" "Group enriched" "Detected in some" 4 "HAP1: 16.4;Karpas-707: 61.9" "Low region specificity" "Detected in all" HPA059058 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA059058: AB_2683894" "unprognostic (1.88e-2)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (2.63e-3)" "unprognostic (5.03e-2)" "unprognostic (1.94e-1)" "unprognostic (5.25e-2)" "prognostic favorable (3.09e-4)" "unprognostic (1.23e-1)" "unprognostic (2.83e-2)" "unprognostic (4.97e-3)" "unprognostic (4.63e-2)" "prognostic favorable (1.97e-4)" "unprognostic (3.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.26e-2)" "unprognostic (2.48e-2)" 3.2 15.6 73.5 3.7 73.2 2.1 7.7 56.0 124.0 4.3 45.0 5.1 4.0 6.3 33.3 1.9 5.0 13.0 5.6 73.4 116.1 20.4 3.5 13.6 4.9 73.0 72.1 13.7 26.3 33.7 77.5 0.0 79.7 6.6 6.1 30.8 7.6 3.7 0.5 3.4 3.3 3.4 59.5 4.4 8.2 13.1 84.0 1.1 25.8 0.5 7.8 2.1 3.4 75.2 0.0 0.0 0.0 0.0 0.6 0.0 2.3 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.9 0.0 0.3 1.4 16.4 0.3 0.0 0.0 0.8 5.5 0.0 0.0 0.1 0.0 2.5 0.0 0.2 0.0 2.4 0.4 0.1 6.0 2.5 61.9 0.3 7.1 0.4 0.1 7.3 0.0 2.6 0.0 0.0 0.2 5.8 0.0 8.9 0.9 0.1 0.1 0.0 1.2 1.6 0.0 6.0 0.4 4.2 0.5 0.0 7.1 4.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 6.2 0.0 15.5 2.1 11.6 8.1 0.1 0.9 16.4 10.1 0.0 10.1 0.0 0.8 11.9 2.9 73.5 73.2 56.0 124.0 73.4 116.1 73.0 72.1 79.7 59.5 84.0 75.2 9.0 3.2 5.6 4.2 12.2 14.9 24.2 0.1 10.2 53.2 25.9 32.1 19.4 171.6 7.4 38.6 0.0 0.0 13.4 2.1 137.0 16.5 1.3 6.7 0.7 16.3 35.9 1.7 18.1 22.8 0.1 5.8 2.6 8.4 22.8 25.1 26.7 18.2 0.3 57.2 14.0 31.9 0.0 0.8 6.2 7.0 2.5 1.3 30.2 6.5 6.0 55.5 7.2 6.6 3.5 8.5 2.5 0.4 24.5 16.4 0.5 23.2 6.8 25.4 0.0 8.8 2.3 2.1 1.2 4.3 11.2 0.0 13.4 21.5 6.2 11.0 BNC2 "BSN2, FLJ20043" ENSG00000173068 "Basonuclin 2" Q6ZN30 9 16409503-16870843 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 26.9;ovary: 31.7;smooth muscle: 31.7" "Cell type enhanced" "Detected in many" "Astrocytes: 46.7;Leydig cells: 90.1;Microglial cells: 230.5;Peritubular cells: 67.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "gdT-cell: 2.5" "Lineage enriched" "Detected in single" 5 "T-cells: 2.5" "Cell line enhanced" "Detected in many" "HSkMC: 31.9;Karpas-707: 40.4;RPMI-8226: 28.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA018525, HPA059419" Approved Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA018525: AB_1845402, HPA059419: AB_2732637" "unprognostic (2.68e-1)" "unprognostic (2.89e-1)" "unprognostic (3.64e-2)" "unprognostic (1.14e-2)" "unprognostic (1.56e-2)" "unprognostic (5.07e-2)" "unprognostic (2.81e-2)" "unprognostic (2.50e-1)" "unprognostic (1.94e-2)" "unprognostic (6.05e-2)" "unprognostic (5.99e-2)" "unprognostic (3.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.36e-2)" "unprognostic (1.62e-1)" "unprognostic (6.74e-2)" "unprognostic (1.14e-3)" 5.6 1.0 1.4 3.7 2.5 0.7 3.3 2.3 4.4 12.1 8.2 10.1 1.3 26.9 2.1 4.6 18.4 7.2 2.9 2.6 2.7 6.4 0.3 3.1 0.8 4.7 6.0 31.7 0.5 2.9 1.7 3.4 3.9 3.7 3.0 0.8 1.3 4.8 3.5 3.4 3.3 31.7 3.5 0.7 3.0 6.9 4.7 2.5 2.1 1.9 1.1 6.3 5.8 4.9 0.3 1.7 1.2 0.1 17.5 21.1 2.7 11.4 19.5 7.8 6.4 0.1 0.0 0.0 3.7 7.8 5.8 0.1 5.1 0.0 7.9 0.2 2.0 0.1 5.3 0.0 13.4 0.1 0.5 31.9 0.0 16.6 0.1 13.7 18.0 0.0 0.0 40.4 11.1 0.0 0.0 2.8 6.6 0.1 10.2 0.0 12.5 28.0 6.0 0.3 0.2 1.0 0.1 0.1 18.6 8.3 0.1 0.0 17.7 18.6 13.5 15.1 20.9 0.2 0.0 0.1 7.6 2.5 2.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 1.5 1.4 2.5 2.3 4.4 2.6 2.7 4.7 6.0 3.9 3.5 4.7 4.9 5.5 0.0 2.2 46.7 0.0 10.1 0.6 0.0 33.6 8.2 0.2 0.4 4.8 0.0 0.6 0.0 0.0 3.2 10.7 0.1 0.0 1.0 7.2 2.2 9.1 10.5 0.0 0.0 1.6 0.4 1.2 38.6 3.1 2.0 22.2 25.1 10.4 0.3 7.3 0.0 1.9 1.1 6.1 1.6 2.3 4.5 90.1 4.2 10.6 230.5 0.1 2.6 30.9 1.0 1.6 0.1 0.0 67.7 3.9 0.7 5.7 35.5 0.7 0.3 6.6 31.5 5.1 0.9 13.5 5.7 5.5 1.2 3.1 36.5 1.8 0.1 BSCL2 "GNG3LG, seipin, SPG17" ENSG00000168000 "BSCL2 lipid droplet biogenesis associated, seipin" Q96G97 11 62690275-62709845 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid degradation, Lipid metabolism" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 292.1;pituitary gland: 237.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 35.9;Late spermatids: 53.1;Plasma cells: 86.3;Spermatocytes: 32.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 242.1;RPMI-8226: 176.1;SCLC-21H: 181.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042394 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA042394: AB_10794047" "unprognostic (7.78e-2)" "unprognostic (8.74e-2)" "unprognostic (1.24e-1)" "unprognostic (8.17e-2)" "unprognostic (3.08e-2)" "unprognostic (2.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (9.30e-2)" "unprognostic (4.44e-2)" "unprognostic (5.13e-3)" "unprognostic (2.41e-1)" "prognostic favorable (7.55e-5)" "unprognostic (3.56e-1)" "unprognostic (1.69e-1)" "unprognostic (1.70e-1)" "unprognostic (1.96e-1)" 24.9 88.1 126.6 7.4 133.2 12.0 26.2 75.0 155.6 38.2 85.4 24.3 10.8 28.4 156.7 24.1 63.7 21.5 18.7 134.9 292.1 50.8 39.3 26.7 15.3 138.1 139.0 32.7 79.4 61.7 237.0 10.0 203.4 35.4 13.3 52.6 66.1 30.3 30.9 25.1 17.2 13.7 83.1 16.2 37.1 190.3 169.3 14.4 37.9 15.5 8.9 17.5 26.1 89.9 18.0 61.7 49.6 83.8 130.8 41.5 7.2 7.2 34.4 13.6 14.5 9.6 26.3 11.9 16.5 25.2 11.8 62.1 5.2 21.8 7.0 30.7 5.0 10.9 33.4 7.8 27.7 9.7 13.5 27.8 16.6 26.9 10.9 19.7 10.8 33.0 7.8 242.1 19.8 44.0 11.4 21.8 132.4 13.9 13.0 21.3 4.2 176.1 65.0 2.4 181.2 29.4 28.2 13.9 25.3 5.7 41.3 15.3 6.5 16.5 3.7 24.5 4.2 32.2 72.5 16.6 82.4 3.2 14.5 26.6 59.2 34.6 24.7 46.2 27.4 27.5 25.5 26.1 42.4 29.7 25.7 27.0 14.2 41.0 40.3 54.3 33.1 43.3 126.6 133.2 75.0 155.6 134.9 292.1 138.1 139.0 203.4 83.1 169.3 89.9 0.8 16.0 5.6 0.0 7.1 1.7 1.0 1.4 35.9 2.5 3.6 2.2 0.2 1.5 1.6 3.7 0.0 2.4 0.9 1.7 3.9 2.0 25.5 4.8 1.5 2.9 0.0 8.8 0.0 1.1 1.9 9.2 20.4 1.5 2.5 0.7 1.4 2.1 1.9 3.3 0.0 1.6 6.1 2.5 3.1 53.1 2.5 6.2 12.4 0.0 0.7 0.8 1.0 0.0 0.0 0.5 1.6 3.0 86.3 0.9 2.5 6.0 23.9 1.2 6.6 1.2 4.1 32.6 18.1 24.7 4.0 1.5 6.5 0.7 1.2 0.5 BST2 "CD317, tetherin" ENSG00000130303 "Bone marrow stromal cell antigen 2" Q10589 19 17402939-17405630 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, B-cell activation, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 694.2" "Cell type enhanced" "Detected in many" "Adipocytes: 1193.2;Hepatic stellate cells: 455.8;Theca cells: 490.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 615.0;Karpas-707: 603.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA017060, HPA073472" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 260000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles" "HPA017060: AB_1845467, HPA073472: " "prognostic favorable (6.69e-4)" "unprognostic (1.75e-1)" "unprognostic (8.42e-3)" "unprognostic (8.93e-3)" "unprognostic (4.87e-2)" "unprognostic (2.25e-1)" "unprognostic (2.26e-1)" "unprognostic (1.07e-1)" "unprognostic (3.25e-1)" "unprognostic (6.46e-2)" "unprognostic (6.56e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.56e-9)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.08e-1)" "unprognostic (2.46e-2)" 226.0 509.8 86.7 95.6 87.6 103.7 152.9 84.0 125.7 93.4 81.7 94.1 47.4 58.7 59.5 40.3 248.0 109.4 111.2 85.1 84.5 160.1 227.8 141.4 128.0 101.5 85.9 694.2 26.3 13.8 56.8 203.0 88.4 88.6 33.3 2.0 77.7 105.2 46.1 24.8 109.1 76.0 97.0 238.5 84.1 35.4 91.1 123.5 54.0 50.8 65.8 82.9 88.6 90.8 327.0 0.5 0.9 145.6 0.0 1.0 49.6 1.3 24.9 459.5 615.0 150.5 286.1 252.2 338.2 197.6 14.6 1.3 212.9 23.9 14.3 279.1 1.8 3.6 525.7 149.8 256.7 120.1 304.7 1.3 0.0 153.0 0.1 4.4 119.0 6.0 146.3 603.4 0.0 89.5 57.7 208.6 158.0 0.1 407.9 105.5 0.8 530.7 110.1 1.5 0.6 1.4 325.5 12.3 410.5 12.3 243.1 166.3 1.5 1.9 11.4 0.5 3.3 308.3 439.3 168.0 1.3 470.8 2.2 229.7 345.3 125.3 171.4 385.5 163.0 115.2 143.2 160.0 283.8 146.5 114.8 132.6 113.3 353.2 359.3 421.7 143.3 367.9 86.7 87.6 84.0 125.7 85.1 84.5 101.5 85.9 88.4 97.0 91.1 90.8 1193.2 57.7 13.6 4.9 90.7 33.1 19.6 255.7 48.9 0.2 86.2 168.5 7.0 50.1 68.5 49.7 0.0 7.8 184.2 1.5 37.2 18.7 10.7 27.8 11.2 420.2 1.2 74.0 0.0 1.2 61.5 152.4 14.8 50.1 227.8 260.9 455.8 211.1 388.9 0.0 0.0 2.8 28.5 189.4 187.6 12.0 346.7 220.4 74.7 32.8 214.5 1.3 211.2 0.5 0.3 3.3 4.8 419.4 192.8 10.3 3.7 1.3 27.4 2.1 164.3 30.7 146.3 1.3 1.2 15.5 26.1 13.1 135.8 490.6 5.0 28.6 BTG4 "APRO3, PC3B" ENSG00000137707 "BTG anti-proliferation factor 4" Q9NY30 11 111467526-111512354 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 26.4" "Group enriched" "Detected in some" 6 "Early spermatids: 61.3;Late spermatids: 80.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.3;Karpas-707: 4.5;U-266/70: 3.1;U-266/84: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA057157 Approved "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum, Golgi apparatus" "HPA057157: AB_2683354" "unprognostic (1.58e-1)" "unprognostic (2.68e-3)" "unprognostic (3.20e-2)" "unprognostic (2.80e-4)" "unprognostic (1.42e-2)" "unprognostic (3.14e-1)" "unprognostic (9.39e-2)" "unprognostic (1.31e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 5.2 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.2 0.2 0.0 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 26.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.1 0.2 3.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.5 0.0 4.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.0 0.2 3.1 1.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 0.7 1.0 0.5 0.4 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.3 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 80.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 10.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BTN2A2 "BT2.2, BTF2, BTN2.2" ENSG00000124508 "Butyrophilin subfamily 2 member A2" Q8WVV5 6 26383096-26394874 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 30.3;Plasma cells: 30.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 72.8;U-266/70: 58.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA051504 Uncertain Approved Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "HPA051504: AB_2681510" "prognostic favorable (1.01e-4)" "unprognostic (4.93e-3)" "unprognostic (1.37e-2)" "unprognostic (6.78e-2)" "unprognostic (9.26e-2)" "unprognostic (2.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.04e-3)" "unprognostic (1.01e-1)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (1.93e-1)" "unprognostic (1.73e-2)" "unprognostic (3.45e-1)" "unprognostic (6.54e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-3)" 7.2 13.5 5.4 21.9 6.9 4.3 8.7 14.4 6.0 7.9 21.2 8.0 7.2 10.2 7.5 5.1 8.4 8.5 4.9 6.8 5.9 7.5 6.1 16.2 32.1 7.5 6.9 10.4 5.2 17.5 5.7 4.0 7.8 8.3 10.5 2.9 12.1 6.8 2.8 11.0 11.3 10.9 6.5 21.8 10.4 6.1 6.2 15.2 7.5 4.2 36.6 8.2 6.9 6.9 10.6 6.6 13.2 14.2 4.4 6.8 0.9 11.4 29.7 17.4 30.0 4.2 4.1 9.6 12.1 20.5 14.1 9.5 10.7 8.7 23.1 29.9 17.9 15.0 13.2 8.4 9.1 3.4 5.1 14.5 2.7 33.5 11.3 20.7 16.3 18.5 12.3 72.8 7.9 4.6 12.1 4.4 5.0 0.4 6.6 28.1 18.7 29.8 12.7 5.9 12.6 17.6 7.4 2.8 31.1 7.5 13.5 6.6 19.5 6.4 7.3 5.6 17.7 58.9 38.8 16.9 6.4 13.4 16.3 2.1 13.7 2.4 6.1 14.6 5.8 24.1 5.0 5.7 23.9 29.4 4.1 5.1 12.4 8.7 6.3 9.7 10.3 7.9 5.4 6.9 14.4 6.0 6.8 5.9 7.5 6.9 7.8 6.5 6.2 6.9 8.1 9.6 12.6 0.0 30.3 3.8 7.3 6.5 6.2 0.6 5.2 5.1 2.5 2.8 8.5 3.7 0.0 2.3 15.0 0.6 0.0 8.6 0.4 8.8 4.5 13.1 1.8 3.6 0.0 5.6 0.8 5.0 3.6 7.5 19.6 9.6 6.1 3.8 8.4 0.0 0.0 7.8 12.2 16.0 24.2 0.6 6.5 17.1 7.2 0.0 15.4 14.3 7.2 0.0 0.0 8.3 0.8 4.9 30.7 6.4 2.6 2.3 10.2 0.7 0.0 5.0 4.4 0.3 1.5 4.5 4.5 1.0 10.0 10.6 2.1 4.2 C16orf86 FLJ41802 ENSG00000159761 "Chromosome 16 open reading frame 86" Q6ZW13 16 67666814-67668757 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 39.8" "Group enriched" "Detected in many" 4 "Early spermatids: 136.7;Spermatocytes: 100.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HSkMC: 3.3;T-47d: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA073475 Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA073475: AB_2686607" "unprognostic (1.01e-2)" "unprognostic (1.38e-2)" "unprognostic (6.33e-2)" "unprognostic (5.20e-2)" "unprognostic (2.16e-1)" "unprognostic (9.68e-3)" "unprognostic (1.33e-1)" "unprognostic (2.87e-2)" "unprognostic (4.05e-1)" "unprognostic (8.35e-3)" "prognostic favorable (1.47e-4)" "unprognostic (1.59e-1)" "prognostic favorable (2.12e-7)" "unprognostic (1.34e-1)" "unprognostic (4.22e-1)" "unprognostic (5.92e-2)" "unprognostic (3.05e-1)" 3.5 2.7 2.3 0.9 2.3 0.6 3.4 2.0 2.8 3.0 2.1 4.1 0.3 3.5 0.3 1.4 3.5 2.2 3.2 1.9 2.5 4.3 2.2 2.0 1.5 2.6 2.4 2.1 2.4 2.6 2.4 1.1 2.4 2.4 0.5 0.7 1.7 1.5 4.6 1.7 1.8 0.5 2.2 2.4 1.9 39.8 2.3 1.9 2.6 2.7 0.5 3.3 2.1 2.7 0.1 0.3 0.6 0.2 0.9 0.8 0.6 0.8 1.8 0.4 0.6 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.0 1.7 0.0 0.9 3.3 0.0 0.5 0.1 0.6 0.7 1.2 0.1 2.0 0.9 0.0 0.1 0.4 0.3 0.3 0.0 1.3 0.0 1.5 1.8 0.1 0.4 0.2 0.0 0.0 0.0 0.1 2.1 0.3 0.0 0.1 0.0 0.4 0.0 0.3 0.6 0.6 0.7 0.1 0.1 1.1 2.3 3.0 0.7 0.7 1.2 1.9 1.8 1.0 3.8 3.6 0.5 1.1 0.8 0.8 0.7 7.4 1.2 1.8 2.3 2.3 2.0 2.8 1.9 2.5 2.6 2.4 2.4 2.2 2.3 2.7 6.2 0.0 3.7 5.5 5.8 1.5 2.4 2.6 3.4 7.5 3.6 4.1 1.9 4.3 2.7 5.5 6.2 1.5 5.2 0.3 7.9 3.3 136.7 1.3 3.5 4.8 3.0 0.8 1.1 0.7 0.4 5.6 0.0 0.9 11.4 2.6 5.7 3.1 6.2 5.0 1.9 0.8 2.0 6.0 4.7 25.7 5.6 5.9 3.6 4.7 5.4 13.5 5.2 2.0 2.3 0.9 0.2 7.5 4.5 0.7 0.2 17.8 1.7 8.4 0.0 5.4 4.0 100.9 3.0 1.1 1.6 0.8 2.5 9.2 0.3 0.9 C17orf49 "BAP18, HEPIS, MGC49942" ENSG00000258315 "Chromosome 17 open reading frame 49" Q8IXM2 17 7014495-7017525 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 62.0;Smooth muscle cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA022961, HPA024457" Supported Uncertain Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA022961: AB_1845592, HPA024457: AB_1845593" "unprognostic (1.48e-2)" "unprognostic (1.67e-3)" "unprognostic (9.09e-2)" "unprognostic (5.15e-2)" "unprognostic (4.54e-1)" "unprognostic (3.27e-2)" "unprognostic (2.38e-1)" "unprognostic (7.62e-2)" "unprognostic (2.27e-2)" "unprognostic (4.06e-2)" "unprognostic (2.25e-2)" "unprognostic (1.49e-2)" "unprognostic (1.06e-9)" "unprognostic (5.68e-2)" "unprognostic (1.74e-1)" "unprognostic (1.41e-2)" "unprognostic (4.62e-2)" 62.3 42.6 54.9 61.5 54.6 122.1 55.5 55.6 60.4 42.1 49.3 37.8 34.9 36.0 53.1 52.8 49.3 38.2 53.1 53.7 55.4 47.2 47.1 55.3 97.5 54.6 54.0 35.6 50.8 37.7 40.1 36.9 54.1 35.3 42.3 39.2 42.2 26.8 69.6 63.1 37.0 34.0 54.6 73.0 35.5 28.2 57.2 97.6 52.9 55.1 105.4 53.9 39.5 55.9 68.2 88.3 136.8 106.6 95.4 134.5 47.0 36.1 58.7 70.8 57.5 43.6 54.5 64.6 97.1 86.8 23.0 55.1 34.5 69.8 53.7 227.6 91.6 58.4 27.9 85.3 71.6 37.7 74.8 85.4 92.4 52.9 106.0 50.7 112.0 51.6 21.9 179.3 87.5 77.7 62.3 125.1 45.9 77.1 51.2 38.3 40.0 95.1 80.9 44.6 37.2 105.3 63.4 32.3 67.5 49.1 41.0 47.9 61.7 40.8 50.3 69.7 93.5 63.8 39.5 22.5 63.6 55.6 59.9 259.3 159.7 157.7 190.8 225.8 122.3 238.7 195.9 193.8 251.3 221.0 128.9 143.0 148.1 391.4 177.4 346.7 215.3 193.1 54.9 54.6 55.6 60.4 53.7 55.4 54.6 54.0 54.1 54.6 57.2 55.9 9.6 3.2 10.3 0.0 18.2 10.5 5.9 8.2 13.1 1.2 8.9 11.2 1.1 2.8 7.2 1.8 0.0 10.9 18.1 8.2 17.6 17.7 0.2 2.3 4.1 12.3 30.6 8.6 0.0 23.1 16.5 6.0 2.6 4.2 18.9 3.1 9.3 2.1 11.1 0.0 0.0 12.5 14.2 7.8 32.3 1.4 4.1 12.0 24.9 0.0 62.0 2.1 16.5 0.0 0.0 24.2 14.3 1.5 14.1 6.6 8.8 6.0 4.1 3.5 6.6 6.1 41.9 5.4 18.5 11.9 11.8 10.4 17.6 3.3 14.0 6.2 C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945672 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 477.9" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 142.4;Hepatocytes: 380.3;Hofbauer cells: 282.7;Kupffer cells: 99.3" "Cancer enriched" "Detected in all" 9 "liver cancer: 100.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "intermediate monocyte: 21.1;non-classical monocyte: 25.9" "Lineage enriched" "Detected in single" 35 "monocytes: 25.9" "Cell line enriched" "Detected in some" 5 "Karpas-707: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB016775 Supported "Secreted to blood" NA NA 34000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB016775: " "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (1.49e-3)" "unprognostic (7.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.36e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-1)" "unprognostic (2.59e-3)" "unprognostic (3.27e-2)" "unprognostic (3.15e-3)" "prognostic unfavorable (2.64e-7)" "unprognostic (2.05e-1)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.55e-2)" 42.6 12.1 0.8 27.6 1.0 3.2 11.7 0.9 1.4 8.1 1.7 14.3 16.7 7.0 1.3 7.6 12.0 23.0 8.5 0.7 1.1 23.2 477.9 80.0 27.8 3.0 2.6 5.3 1.9 0.9 3.8 48.4 3.0 5.4 13.0 0.4 9.1 0.9 2.1 5.8 30.2 23.6 2.1 46.3 12.0 4.1 3.7 5.5 3.3 2.7 12.5 23.6 5.3 2.1 0.3 0.1 0.1 0.6 0.1 0.0 6.8 0.5 0.3 0.4 0.3 0.4 0.3 0.6 3.5 1.0 0.6 0.5 0.1 0.0 0.3 0.2 0.4 0.3 0.4 52.8 1.1 0.1 0.7 2.7 0.3 0.6 0.1 0.6 0.0 0.7 0.5 284.0 0.0 0.0 0.4 0.5 0.3 0.1 0.0 0.2 16.5 3.0 0.0 0.1 0.3 0.3 2.6 0.3 0.2 0.3 0.2 9.5 0.2 0.2 0.7 0.5 0.1 0.9 31.6 2.7 0.8 0.9 0.1 0.1 5.6 0.0 0.1 21.1 0.1 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.5 0.1 25.9 0.0 0.0 2.2 0.8 1.0 0.9 1.4 0.7 1.1 3.0 2.6 3.0 2.1 3.7 2.1 2.1 25.6 142.4 2.6 1.9 3.3 1.1 2.0 0.6 1.4 1.3 1.3 0.6 25.8 11.2 1.8 0.0 2.1 0.1 1.8 0.0 0.6 0.3 1.5 18.7 1.9 2.4 10.7 6.6 2.7 2.7 19.8 3.1 1.3 3.8 0.2 21.0 380.3 282.7 1.7 6.3 11.3 0.0 99.3 5.0 1.3 6.8 32.6 3.6 7.5 7.3 0.1 0.0 1.0 1.7 4.5 33.1 1.2 0.4 4.0 55.2 35.7 9.4 0.9 0.0 5.6 3.5 0.8 1.4 0.7 2.8 4.0 2.0 0.5 15.8 4.5 C21orf91 "C21orf14, C21orf38, CSSG1, EURL, YG81" ENSG00000154642 "Chromosome 21 open reading frame 91" Q9NYK6 21 17788974-17819386 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.0" "Cell type enhanced" "Detected in many" "Early spermatids: 345.8;Late spermatids: 98.6;Oligodendrocytes: 103.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 111.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 107.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018288, HPA049030" Approved Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Microtubules "Cytokinetic bridge" "HPA018288: AB_1845710, HPA049030: AB_2680605" "unprognostic (3.28e-1)" "unprognostic (3.41e-2)" "unprognostic (3.12e-2)" "unprognostic (4.51e-2)" "unprognostic (6.19e-2)" "unprognostic (1.11e-3)" "unprognostic (2.42e-1)" "unprognostic (8.81e-3)" "unprognostic (2.79e-1)" "unprognostic (1.97e-1)" "unprognostic (3.25e-1)" "unprognostic (5.49e-2)" "unprognostic (1.24e-2)" "unprognostic (6.80e-2)" "unprognostic (1.59e-1)" "unprognostic (6.49e-2)" "unprognostic (9.90e-3)" 6.3 4.8 11.5 9.8 26.7 8.2 8.2 22.0 16.3 6.2 4.4 4.7 5.1 9.2 4.3 8.3 6.7 6.0 5.4 13.3 15.5 5.3 8.7 7.9 15.4 26.0 21.2 8.0 2.8 4.9 2.7 13.5 26.6 5.3 5.2 5.7 5.0 3.6 2.7 18.9 5.5 7.6 20.9 9.8 6.3 24.4 20.7 19.2 5.7 5.5 13.0 8.3 4.1 59.0 7.2 1.2 15.6 0.1 3.9 7.3 6.9 10.4 18.6 10.1 8.9 6.5 3.7 25.2 5.1 4.2 14.1 5.7 17.1 13.4 8.7 27.5 9.2 16.9 13.2 4.1 8.8 20.6 9.2 5.3 14.6 13.3 21.5 7.1 2.8 10.3 12.1 107.9 7.7 4.5 28.8 6.1 16.4 1.7 5.7 21.9 29.9 10.2 6.8 12.0 6.2 14.4 13.1 10.1 47.2 7.0 6.1 11.6 4.8 44.2 13.8 0.2 6.8 28.6 37.7 21.5 3.5 18.9 17.3 111.1 11.2 56.8 20.9 11.9 29.8 14.0 19.3 22.7 13.9 11.7 14.9 19.7 24.9 20.7 12.2 3.5 36.9 12.0 11.5 26.7 22.0 16.3 13.3 15.5 26.0 21.2 26.6 20.9 20.7 59.0 20.2 19.2 11.1 1.6 26.4 27.9 10.1 57.9 63.2 12.6 14.4 10.4 7.4 4.3 27.1 5.5 16.7 17.3 18.8 4.4 1.9 4.8 345.8 14.5 13.8 21.3 10.7 5.5 0.8 6.9 12.2 12.0 9.2 14.4 39.9 11.3 7.5 6.8 5.8 15.2 0.8 5.0 18.3 7.2 14.0 98.6 23.6 9.7 21.4 3.7 30.7 3.5 48.4 7.5 103.4 4.4 5.9 17.0 27.6 11.0 3.4 6.4 19.3 13.0 6.6 20.1 12.1 38.7 24.1 21.4 27.6 80.2 38.9 22.1 3.8 7.7 C2orf42 FLJ20558 ENSG00000115998 "Chromosome 2 open reading frame 42" Q9NWW7 2 70149885-70248615 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 59.0" "Cell type enhanced" "Detected in many" "Early spermatids: 262.9;Late spermatids: 98.5;Spermatocytes: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031840, HPA031841, HPA031842" Enhanced Enhanced Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA031840: AB_2674066, HPA031841: AB_10601124, HPA031842: AB_2674068" "unprognostic (8.49e-2)" "unprognostic (2.09e-1)" "unprognostic (2.52e-1)" "unprognostic (1.03e-1)" "unprognostic (1.51e-1)" "unprognostic (3.41e-1)" "unprognostic (1.92e-1)" "unprognostic (2.20e-3)" "unprognostic (2.26e-1)" "unprognostic (3.73e-1)" "prognostic favorable (5.94e-5)" "unprognostic (4.66e-2)" "unprognostic (9.41e-2)" "unprognostic (2.11e-2)" "unprognostic (1.43e-1)" "unprognostic (2.84e-1)" "unprognostic (2.49e-3)" 6.5 7.3 11.2 5.9 12.7 4.8 6.4 16.3 12.5 7.8 10.6 6.5 4.4 8.5 10.9 6.4 11.2 7.5 5.8 10.4 11.7 8.4 15.4 6.0 12.4 10.8 11.5 10.2 6.7 11.5 7.8 8.0 11.5 6.7 5.2 7.5 6.4 7.2 6.7 6.7 6.3 7.5 10.9 8.8 6.1 59.0 11.9 10.1 8.2 8.4 11.6 8.2 6.2 16.1 5.9 9.6 8.9 8.1 17.9 10.4 10.1 13.9 9.4 11.0 9.4 7.8 5.1 7.5 7.9 8.3 18.0 8.0 9.4 7.9 12.2 13.1 8.3 8.8 6.8 7.7 15.9 7.3 8.6 12.5 14.1 10.5 13.3 12.0 10.8 9.4 7.5 27.6 14.7 4.6 9.4 10.7 6.4 9.9 10.6 8.8 12.1 13.8 9.0 6.8 7.4 7.5 7.5 11.6 14.4 6.2 5.2 8.9 8.5 9.8 6.7 9.1 11.4 15.1 16.2 7.5 7.6 11.8 8.9 2.3 7.7 9.9 12.1 7.2 15.5 14.2 12.2 14.7 7.9 13.0 13.9 14.9 8.3 21.9 7.8 7.0 15.5 10.9 11.2 12.7 16.3 12.5 10.4 11.7 10.8 11.5 11.5 10.9 11.9 16.1 4.0 0.0 2.2 7.8 8.9 2.5 3.4 3.7 5.7 5.8 4.0 5.0 2.8 1.5 2.8 5.5 0.0 8.8 6.1 4.2 7.9 4.5 262.9 3.8 3.3 3.6 1.2 4.0 9.2 2.4 4.0 4.4 3.6 2.8 2.5 5.0 6.4 6.9 4.3 0.0 8.9 2.1 2.0 4.7 3.1 98.5 7.5 3.6 3.6 2.8 3.1 9.0 9.2 8.0 12.3 2.0 3.1 7.9 8.4 2.9 3.3 6.4 6.6 4.1 0.0 4.2 3.8 63.1 12.0 3.5 4.3 9.6 5.3 4.3 2.5 2.0 C4B "C4B1, C4B3, C4F, CH, CO4, CPAMD3" ENSG00000224389 "Complement C4B (Chido blood group)" P0C0L5 6 32014795-32035418 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 221.5;liver: 385.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 103.9;Cardiomyocytes: 71.8;Club cells: 22.9;Fibroblasts: 53.9" "Cancer enhanced" "Detected in many" "liver cancer: 33.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 129.8" "HPA046356, HPA048287, HPA050103" Approved "Secreted to blood" NA NA 120000000000 "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (1.29e-1)" "unprognostic (2.99e-2)" "unprognostic (5.50e-3)" "unprognostic (1.30e-1)" "unprognostic (8.09e-2)" "unprognostic (6.24e-2)" "unprognostic (6.09e-2)" "unprognostic (1.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.12e-1)" "unprognostic (6.24e-2)" "unprognostic (6.86e-2)" "unprognostic (1.04e-1)" "unprognostic (3.12e-2)" "unprognostic (1.30e-1)" "unprognostic (3.99e-3)" "unprognostic (1.11e-2)" 29.7 221.5 4.0 0.4 2.5 0.6 15.9 2.5 2.3 10.3 2.4 27.3 2.0 16.6 0.0 2.2 24.0 5.9 22.7 3.2 13.3 39.8 385.2 13.6 2.7 7.1 12.4 56.5 25.1 1.1 20.1 1.6 7.7 10.2 6.0 2.5 21.0 1.2 1.3 1.1 16.6 9.7 9.9 16.3 10.3 3.1 11.8 7.5 49.1 0.2 4.3 18.5 3.7 11.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 21.0 7.8 0.5 0.0 26.2 0.1 0.0 0.0 2.6 0.0 0.0 0.0 129.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.5 2.5 2.3 3.2 13.3 7.1 12.4 7.7 9.9 11.8 11.6 0.0 3.2 103.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 71.8 1.5 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.6 0.0 0.0 0.0 0.2 0.0 53.9 0.0 0.0 1.3 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.1 0.0 0.5 8.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CADPS2 CAPS2 ENSG00000081803 "Calcium dependent secretion activator 2" Q86UW7 7 122318411-122886759 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 96.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 682.7;Microglial cells: 180.8;Oligodendrocyte precursor cells: 111.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 96.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 43.5;Karpas-707: 56.3;OE19: 63.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 159.9" HPA056398 Approved Nucleoplasm,Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "HPA056398: AB_2683117" "unprognostic (1.93e-1)" "unprognostic (5.05e-2)" "unprognostic (1.91e-1)" "unprognostic (3.67e-3)" "unprognostic (8.69e-3)" "unprognostic (9.13e-2)" "unprognostic (1.19e-1)" "unprognostic (1.33e-1)" "unprognostic (4.07e-1)" "unprognostic (4.33e-2)" "unprognostic (3.93e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.01e-7)" "unprognostic (9.93e-2)" "unprognostic (1.37e-1)" "unprognostic (2.71e-2)" "unprognostic (3.45e-2)" 10.3 21.1 9.2 4.5 16.3 0.1 18.3 96.2 30.9 29.8 5.8 10.7 12.6 35.0 30.3 4.5 11.0 15.6 10.2 14.2 14.4 38.3 13.2 18.0 3.5 4.9 40.1 9.9 26.0 12.0 13.8 6.0 7.9 19.4 10.7 7.2 48.3 18.5 2.4 4.0 10.0 21.7 6.2 6.7 20.0 4.0 17.4 4.9 18.3 7.8 3.8 9.3 8.5 18.7 0.0 0.1 3.4 0.0 5.1 5.2 0.3 0.5 13.5 2.9 13.4 0.1 12.6 0.0 0.0 6.4 0.4 0.1 0.4 1.9 1.3 0.0 11.1 4.4 0.1 25.1 16.9 0.0 0.2 5.5 2.4 2.3 1.7 11.8 43.5 0.0 0.0 56.3 0.2 30.9 0.0 0.1 12.6 63.6 21.4 0.0 0.0 23.2 0.6 14.3 20.5 0.0 0.6 24.4 1.2 3.2 9.5 0.1 12.5 4.7 3.1 0.1 8.9 16.8 0.7 0.0 18.1 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 16.3 96.2 30.9 14.2 14.4 4.9 40.1 7.9 6.2 17.4 18.7 29.3 9.6 43.9 85.2 3.1 2.2 7.9 7.3 10.2 0.6 36.7 22.4 12.9 11.5 14.4 40.5 0.0 0.4 0.5 4.3 17.6 4.4 8.5 4.8 13.5 24.7 4.8 0.0 682.7 11.1 0.5 13.0 42.3 11.2 1.3 10.1 14.3 12.5 0.4 3.3 14.2 13.2 10.2 3.1 1.4 6.8 9.6 0.6 3.6 180.8 0.0 27.2 0.0 111.1 11.0 4.8 3.7 10.1 15.7 13.4 5.7 7.9 9.4 1.5 0.0 6.9 6.2 0.7 4.2 6.2 1.4 0.3 0.7 11.3 8.0 8.5 CALN1 CABP8 ENSG00000183166 "Calneuron 1" Q9BXU9 7 71779491-72447151 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 11.3;brain: 44.3;lymphoid tissue: 24.7" "Cell type enhanced" "Detected in some" "Astrocytes: 88.8;Excitatory neurons: 130.6;Inhibitory neurons: 212.7;Oligodendrocyte precursor cells: 44.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Karpas-707: 44.5" "Low region specificity" "Detected in all" "HPA036278, HPA036708" Approved Uncertain "Vesicles,Plasma membrane" No No "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Plasma membrane" "HPA036278: AB_10673125, HPA036708: " "unprognostic (6.38e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-1)" "unprognostic (1.32e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-2)" "unprognostic (3.67e-4)" "unprognostic (3.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.57e-2)" "unprognostic (1.41e-1)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" "unprognostic (3.53e-2)" "unprognostic (1.23e-2)" "unprognostic (7.72e-4)" "unprognostic (2.99e-1)" 0.1 11.3 12.2 0.0 18.5 0.6 0.2 44.3 15.0 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 25.4 40.6 0.0 0.2 0.0 0.0 27.9 17.0 0.1 1.0 0.0 0.5 0.0 30.2 0.2 0.1 1.9 0.0 1.1 0.0 3.5 0.0 0.0 15.2 0.0 0.0 3.2 8.3 24.7 0.1 0.0 0.0 0.0 3.2 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 44.5 0.0 0.0 0.1 0.0 6.0 0.0 0.0 7.1 0.0 0.8 0.0 0.0 6.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 7.2 0.1 0.0 7.0 7.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 18.5 44.3 15.0 25.4 40.6 27.9 17.0 30.2 15.2 8.3 26.5 0.0 0.0 0.0 88.8 0.0 2.3 0.4 0.0 0.0 3.8 0.0 0.6 5.6 5.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.8 0.1 0.1 0.3 0.0 2.1 130.6 0.0 0.0 0.2 0.0 0.4 0.0 0.0 1.4 0.4 0.1 0.0 212.7 1.5 0.0 0.3 0.7 7.0 0.0 0.1 0.0 14.0 0.0 0.2 1.0 44.7 15.7 0.0 0.1 0.7 0.0 0.2 0.0 0.1 0.0 0.8 0.0 6.1 0.2 8.8 12.8 0.0 9.8 0.1 0.2 0.2 0.1 0.1 CARS1 CARS ENSG00000110619 "Cysteinyl-tRNA synthetase 1" P49589 11 3000922-3057613 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 10.3;Cardiomyocytes: 8.8;Cytotrophoblasts: 22.2;Extravillous trophoblasts: 40.7;Hofbauer cells: 22.0;Syncytiotrophoblasts: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737" Enhanced Enhanced Cytosol NA NA 200000 "Cluster 14: Monocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB075734: AB_2665740, CAB075735: AB_2665741, CAB075736: AB_2665742, CAB075737: AB_2665743, HPA002383: AB_1078399, HPA002384: AB_1846033" "unprognostic (9.10e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-3)" "unprognostic (1.43e-1)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (8.00e-2)" "unprognostic (5.51e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "unprognostic (3.46e-1)" 22.1 17.4 8.1 12.0 8.5 7.3 19.9 8.7 21.6 13.6 8.4 21.8 12.0 15.9 7.5 19.2 12.8 10.3 13.3 8.2 9.8 13.7 21.1 17.5 12.7 9.6 9.9 8.9 32.8 9.6 18.6 10.3 10.6 12.7 12.8 5.3 20.6 6.8 31.7 23.8 17.4 16.0 9.7 17.2 23.5 16.8 9.9 14.6 17.3 14.7 17.8 18.1 14.9 11.5 29.2 14.0 17.8 55.6 67.3 61.4 16.2 70.0 78.6 46.7 84.1 34.2 64.7 43.1 20.1 88.2 0.0 68.7 58.3 78.6 64.0 123.7 13.5 24.4 23.7 25.8 161.1 50.9 50.2 102.2 64.1 40.1 46.8 0.0 62.3 103.6 42.2 147.0 47.1 41.9 35.7 0.0 65.2 97.9 25.0 17.2 29.7 54.9 0.0 46.1 39.0 49.7 17.1 48.1 80.1 13.3 0.0 0.1 21.8 19.5 18.2 48.2 0.2 107.8 106.8 27.2 0.1 26.6 40.3 16.3 18.6 13.5 20.9 15.4 17.4 10.9 18.3 18.6 19.4 8.5 9.9 16.0 25.4 23.7 37.9 7.5 27.0 19.2 8.1 8.5 8.7 21.6 8.2 9.8 9.6 9.9 10.6 9.7 9.9 11.5 10.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 22.2 8.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 40.7 3.7 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 32.3 1.4 0.0 0.0 0.0 CASP3 "apopain, CPP32, CPP32B, Yama" ENSG00000164305 "Caspase 3" P42574 4 184627696-184649509 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 118.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 571.0;eosinophil: 408.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 571.0" "Cell line enhanced" "Detected in all" "Karpas-707: 259.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000091, HPA002643, CAB008381" Enhanced Approved Nucleoplasm,Mitochondria NA NA 94000 "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Mitochondria Nucleoplasm "CAB000091: , CAB008381: AB_590737, HPA002643: AB_1846048" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "prognostic favorable (2.24e-4)" "unprognostic (2.29e-3)" "unprognostic (3.58e-2)" "unprognostic (9.57e-3)" "unprognostic (5.86e-2)" "unprognostic (3.56e-2)" "unprognostic (1.12e-2)" "unprognostic (1.70e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.41e-2)" "unprognostic (5.74e-3)" "unprognostic (1.30e-1)" "unprognostic (4.05e-3)" 16.3 12.1 11.3 26.6 10.9 32.8 16.3 18.6 11.4 12.7 10.0 34.2 54.1 12.7 12.9 27.7 9.2 19.9 14.7 10.8 12.2 8.5 22.0 12.8 43.4 10.8 11.5 8.9 13.4 9.0 8.8 26.1 11.4 11.3 33.9 12.7 13.2 10.6 13.9 16.1 41.8 15.3 11.6 23.0 31.2 9.3 11.3 39.0 10.6 14.1 41.9 24.4 12.0 13.0 31.0 16.7 65.3 31.6 39.4 52.2 37.6 90.2 67.7 61.9 35.4 30.7 25.2 42.4 13.9 44.1 29.2 25.5 52.1 32.1 69.7 109.9 28.7 68.2 12.9 71.4 47.3 55.9 62.3 71.7 38.3 39.3 31.4 44.4 77.6 43.1 57.2 259.8 64.5 13.2 89.1 51.8 65.1 33.7 20.9 63.6 30.8 41.2 52.9 49.3 37.1 40.5 39.1 35.1 52.1 64.3 19.2 35.9 54.1 28.2 25.9 21.1 42.4 118.9 121.6 29.2 34.2 38.5 40.9 571.0 26.1 408.6 32.1 43.3 34.4 26.0 29.5 46.3 33.3 18.6 22.2 32.8 35.6 62.0 71.0 26.5 64.1 47.5 11.3 10.9 18.6 11.4 10.8 12.2 10.8 11.5 11.4 11.6 11.3 13.0 28.6 19.2 15.8 26.4 32.3 48.7 22.2 34.1 35.9 18.6 21.7 17.0 17.5 5.7 36.3 12.9 0.0 46.9 54.8 37.4 13.7 18.4 9.6 24.9 17.1 26.6 18.0 62.3 9.6 23.7 33.6 19.5 24.5 24.9 17.7 24.8 21.0 15.3 23.9 13.5 12.6 37.6 44.7 27.0 17.4 4.0 7.5 33.3 30.2 13.1 41.5 15.4 37.0 11.1 18.4 25.0 18.8 7.5 118.6 20.1 26.6 8.4 30.4 11.3 13.1 19.0 20.8 7.9 16.4 34.6 28.6 51.4 43.8 23.1 24.4 36.7 CASP6 MCH2 ENSG00000138794 "Caspase 6" P55212 4 109688622-109703583 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 40.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003775, HPA011337, HPA024303" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 9: Intestine - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol Nucleoplasm "CAB003775: AB_562064, HPA011337: AB_1846053, HPA024303: AB_1846052" "unprognostic (1.07e-1)" "unprognostic (1.91e-1)" "prognostic favorable (2.64e-5)" "unprognostic (1.45e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-1)" "unprognostic (3.03e-3)" "unprognostic (9.87e-2)" "unprognostic (2.73e-2)" "unprognostic (2.59e-3)" "unprognostic (1.15e-2)" "unprognostic (6.78e-2)" "unprognostic (2.44e-1)" "unprognostic (8.74e-3)" "unprognostic (2.18e-1)" "unprognostic (2.41e-1)" "prognostic favorable (9.93e-4)" 6.5 6.7 3.9 8.4 4.0 10.8 10.5 4.3 5.4 7.6 4.0 35.3 40.8 7.7 5.1 7.4 7.6 9.3 5.6 3.8 4.0 11.5 18.1 7.8 9.6 3.7 3.7 8.3 13.3 4.8 4.2 4.8 3.8 9.1 31.5 3.0 8.6 6.5 3.3 10.7 36.8 7.4 3.8 8.0 15.8 1.8 3.7 11.5 8.5 2.4 7.7 8.1 7.0 4.3 26.6 8.4 16.5 14.8 11.0 11.2 24.3 15.3 9.2 12.4 13.4 13.8 50.3 2.7 16.4 14.7 17.3 12.1 19.7 21.8 8.4 43.5 13.0 22.8 7.1 12.9 9.4 23.5 15.7 12.6 15.1 12.4 2.8 17.1 22.9 30.1 29.9 76.1 19.2 13.7 62.0 14.4 12.7 17.1 16.1 20.5 10.8 13.3 39.6 24.8 17.2 13.2 15.0 25.7 8.8 19.6 11.0 8.0 20.3 12.8 14.6 6.6 16.7 11.4 23.0 2.8 17.1 26.9 7.1 16.3 6.9 8.9 6.3 6.9 7.0 6.1 23.8 12.3 8.8 8.6 28.0 16.1 1.4 7.5 11.2 11.6 24.8 9.4 3.9 4.0 4.3 5.4 3.8 4.0 3.7 3.7 3.8 3.8 3.7 4.3 10.5 16.0 14.6 5.2 7.7 10.8 10.2 26.7 12.0 6.9 23.6 16.0 4.1 28.6 23.2 20.2 6.2 20.9 7.6 54.0 9.8 40.8 2.6 19.8 9.5 12.2 59.2 19.7 6.4 46.4 41.1 13.4 18.3 23.3 10.1 112.3 9.7 20.4 19.8 0.0 7.3 53.9 32.6 8.7 9.3 1.7 12.8 14.5 1.8 2.8 17.9 16.0 6.2 5.5 5.8 45.9 52.5 9.8 8.8 7.4 71.7 35.7 18.6 1.3 6.6 7.6 12.3 1.9 8.6 10.8 11.6 5.7 17.5 12.4 74.2 8.0 CBLN3 ENSG00000139899 "Cerebellin 3 precursor" Q6UW01 14 24426545-24430954 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 93.9" "Cell type enhanced" "Detected in some" "dendritic cells: 3.0;Theca cells: 5.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 11 "cerebellum: 93.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 13.4;HDLM-2: 17.2;HSkMC: 23.3;Karpas-707: 18.3;U-266/70: 12.8" "Region enriched" "Detected in many" 25 "cerebellum: 429.5" "Region enriched" "Detected in many" 42 "cerebellum: 446.5" HPA041266 Enhanced Supported Approved Nucleoplasm "Secreted in brain" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA041266: AB_10674430" "unprognostic (5.02e-2)" "unprognostic (3.26e-1)" "unprognostic (1.43e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (4.39e-4)" "unprognostic (5.39e-3)" "unprognostic (1.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.16e-2)" "unprognostic (9.76e-2)" "unprognostic (6.20e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (6.20e-6)" "unprognostic (2.75e-2)" "unprognostic (2.63e-1)" "unprognostic (1.72e-1)" "unprognostic (9.02e-2)" 7.3 17.1 2.7 8.3 3.0 0.6 4.7 93.9 7.0 4.6 2.1 4.2 2.1 2.7 7.4 2.9 4.0 5.6 3.7 2.4 3.3 4.4 6.0 4.8 13.7 3.9 5.8 10.1 2.0 2.9 4.2 3.7 8.4 4.5 2.1 0.5 4.3 3.1 1.8 3.5 5.4 2.2 3.2 13.7 3.3 5.1 3.4 3.9 4.5 0.6 9.1 4.9 4.6 4.8 1.5 1.3 0.7 2.5 6.2 13.4 0.4 5.5 11.1 2.1 2.7 0.7 2.6 2.4 1.2 3.4 2.4 0.3 0.8 2.9 1.4 17.2 0.6 0.0 5.2 1.1 3.3 0.4 0.9 23.3 1.3 2.7 2.1 8.8 1.9 1.0 0.7 18.3 2.8 0.8 0.0 0.7 0.1 1.5 1.5 0.0 0.0 1.8 1.2 0.5 0.9 0.5 0.5 0.1 0.8 0.3 0.8 0.6 8.7 7.7 1.5 3.2 0.3 12.8 3.2 2.7 0.4 1.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.0 93.9 7.0 2.4 3.3 3.9 5.8 8.4 3.2 3.4 4.8 1.4 0.0 0.0 0.0 2.6 0.4 0.6 1.5 0.0 0.0 0.8 1.0 0.5 0.0 0.4 0.0 0.0 0.9 3.0 0.8 0.0 1.1 0.0 0.3 2.0 0.8 0.0 0.4 0.3 1.1 0.6 2.6 0.0 0.5 0.0 0.9 0.0 0.2 0.9 0.0 0.1 0.5 0.0 0.3 0.4 0.3 2.5 0.7 0.0 1.0 2.6 1.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 0.5 0.9 0.8 1.4 0.2 0.0 0.7 1.4 0.0 0.2 0.2 0.6 0.8 0.2 5.7 0.6 0.6 CCDC159 ENSG00000183401 "Coiled-coil domain containing 159" P0C7I6 19 11344684-11354944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 275.7;Late spermatids: 277.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 33.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047126, HPA054655" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA047126: AB_10961722, HPA054655: AB_2682558" "unprognostic (1.46e-1)" "unprognostic (3.05e-3)" "unprognostic (2.35e-3)" "prognostic favorable (1.87e-7)" "unprognostic (5.02e-2)" "unprognostic (1.06e-3)" "unprognostic (9.23e-3)" "unprognostic (2.40e-2)" "unprognostic (6.68e-2)" "prognostic favorable (9.46e-4)" "prognostic favorable (1.42e-4)" "unprognostic (2.89e-1)" "unprognostic (3.97e-2)" "unprognostic (5.09e-2)" "unprognostic (2.46e-1)" "unprognostic (3.00e-2)" "prognostic favorable (8.62e-4)" 15.7 43.4 29.3 17.3 33.8 32.6 18.2 28.9 41.0 30.0 29.2 25.8 22.9 22.5 24.9 18.2 24.0 20.6 21.8 32.3 31.3 25.9 36.0 22.8 20.9 34.4 31.3 31.3 23.3 39.5 33.5 9.3 33.4 45.1 11.8 12.4 21.6 18.5 6.1 19.0 24.0 13.8 27.4 41.8 26.2 43.2 34.2 12.4 30.4 6.7 14.5 24.2 21.7 38.1 3.7 3.2 2.6 8.0 10.3 14.8 2.7 5.8 6.0 6.7 8.9 1.0 3.8 3.0 14.7 11.0 2.0 3.0 1.5 9.2 4.1 15.0 2.2 7.2 2.5 3.9 17.9 2.8 10.4 17.8 24.0 4.9 6.5 7.1 19.2 5.3 6.5 33.6 3.4 4.5 4.5 6.0 1.4 5.0 11.5 4.8 0.0 19.6 6.1 5.3 1.1 4.3 5.9 6.6 11.0 4.6 9.8 11.9 12.8 5.3 1.6 9.3 5.5 30.8 8.0 6.2 7.2 14.7 7.9 51.5 52.8 38.5 21.5 46.3 21.1 16.0 14.6 20.2 31.6 20.4 13.2 10.4 25.3 30.2 33.8 8.4 31.5 23.5 29.3 33.8 28.9 41.0 32.3 31.3 34.4 31.3 33.4 27.4 34.2 38.1 10.7 16.0 13.6 7.5 14.5 7.5 15.4 14.9 10.8 11.3 12.5 8.9 9.8 12.8 16.7 18.4 41.7 5.1 12.4 13.0 25.4 8.2 275.7 9.0 8.8 10.3 10.8 4.6 4.5 9.5 5.5 8.1 30.5 10.0 34.2 11.5 12.8 10.9 23.3 6.7 3.0 12.5 10.2 26.7 14.8 277.4 11.5 20.3 12.4 2.8 28.9 16.6 39.1 2.0 10.2 8.7 24.0 13.5 15.0 16.6 29.2 38.6 16.9 27.9 0.0 5.2 8.4 4.7 3.9 11.0 8.1 6.0 17.9 20.1 9.5 19.7 CCDC88A "APE, FLJ10392, GIV, GRDN, HkRP1, KIAA1212" ENSG00000115355 "Coiled-coil domain containing 88A" Q3V6T2 2 55287842-55419895 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, DNA replication, Neurogenesis" "Guanine-nucleotide releasing factor" "Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.9" "Cell type enhanced" "Detected in many" "Early spermatids: 634.4;Late spermatids: 699.8;Oligodendrocytes: 754.9;Spermatocytes: 429.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 7.4;classical monocyte: 7.2;intermediate monocyte: 7.0;myeloid DC: 11.3;non-classical monocyte: 6.8;plasmacytoid DC: 23.9" "Group enriched" "Detected in all" 7 "dendritic cells: 23.9;granulocytes: 7.4;monocytes: 7.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038101, HPA038102" Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA038101: AB_10670654, HPA038102: AB_2675833" "unprognostic (1.20e-1)" "unprognostic (2.86e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.06e-4)" "unprognostic (1.91e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (4.86e-4)" "unprognostic (8.51e-2)" "unprognostic (1.59e-1)" "unprognostic (1.35e-1)" "unprognostic (3.18e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.98e-8)" "unprognostic (1.42e-2)" "unprognostic (2.61e-1)" "unprognostic (5.74e-3)" "unprognostic (8.96e-3)" 11.4 9.7 48.4 14.0 65.3 15.6 8.4 53.2 77.6 8.7 29.6 9.6 3.8 9.8 3.3 5.4 7.5 7.7 9.2 48.8 54.4 4.7 8.4 14.5 17.2 54.8 60.8 9.3 10.7 3.4 13.2 8.3 57.7 5.9 5.2 26.3 6.7 5.4 7.3 4.2 7.1 9.3 48.8 13.3 6.5 47.3 62.6 18.8 5.8 9.6 15.1 9.6 6.2 80.9 22.8 19.7 45.2 18.3 29.4 24.3 4.0 32.3 30.1 18.9 20.6 2.1 12.0 60.2 19.5 32.6 28.9 0.4 28.9 19.3 46.8 69.8 16.8 41.4 21.7 28.6 12.6 70.7 26.8 15.8 3.8 44.6 28.6 27.1 50.3 48.1 44.9 95.9 51.9 0.2 33.5 41.1 37.4 0.3 24.8 39.7 71.1 0.3 22.9 12.1 23.5 34.8 57.4 0.1 28.9 26.2 1.1 20.2 34.9 54.4 36.5 36.6 39.6 28.8 24.0 25.8 38.0 56.2 23.7 7.4 7.2 2.1 1.4 7.0 0.8 1.8 0.6 1.1 11.3 0.6 0.7 0.6 0.6 1.2 6.8 23.9 0.3 2.1 48.4 65.3 53.2 77.6 48.8 54.4 54.8 60.8 57.7 48.8 62.6 80.9 35.6 12.8 27.9 197.9 25.5 8.4 7.4 11.2 9.1 225.1 7.2 11.9 52.8 4.3 12.8 5.5 37.5 6.5 90.5 0.2 1.9 4.2 634.4 8.0 58.8 41.0 10.8 51.3 317.1 16.8 18.4 38.1 9.2 3.1 152.8 64.4 22.1 18.5 110.8 79.1 318.9 0.0 4.1 142.0 126.7 699.8 29.8 184.2 16.0 129.3 236.1 109.8 11.3 296.6 754.9 31.1 0.2 28.6 114.7 2.9 0.0 8.1 10.1 61.9 32.9 45.1 55.4 429.0 95.5 5.9 6.5 2.3 22.4 82.3 0.1 2.8 CCDC97 "FLJ40267, MGC20255" ENSG00000142039 "Coiled-coil domain containing 97" Q96F63 19 41310172-41324873 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043320, HPA043572" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Plasma membrane, Cytosol" "HPA043320: AB_10964344, HPA043572: AB_10962488" "unprognostic (9.25e-3)" "unprognostic (7.26e-2)" "unprognostic (1.68e-1)" "unprognostic (5.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-2)" "prognostic unfavorable (1.09e-4)" "unprognostic (8.40e-2)" "unprognostic (1.91e-2)" "unprognostic (2.44e-1)" "unprognostic (5.93e-3)" "unprognostic (4.51e-2)" "unprognostic (2.16e-1)" "unprognostic (2.96e-1)" "unprognostic (4.08e-1)" "unprognostic (7.92e-2)" "unprognostic (1.65e-2)" 14.6 12.9 19.0 17.8 21.3 23.0 14.3 17.7 17.7 20.3 14.4 14.0 14.2 17.3 23.4 20.2 21.9 12.3 15.6 16.5 18.2 12.0 11.8 14.3 23.8 23.5 20.2 24.0 17.7 15.8 13.7 10.5 19.9 16.2 11.2 10.7 18.0 14.6 30.6 20.2 16.6 14.2 18.1 20.0 15.7 32.1 20.4 21.9 16.3 20.5 22.2 14.8 17.2 20.5 25.2 54.1 28.2 32.9 36.2 28.7 20.3 16.6 13.4 25.7 21.9 32.4 23.6 23.9 17.4 13.9 17.3 16.7 38.8 33.1 19.5 44.1 37.6 21.9 25.5 21.5 27.5 36.6 45.3 28.1 41.7 30.0 25.0 21.1 18.0 25.8 28.5 44.4 24.9 18.3 33.6 8.9 13.2 30.5 19.3 37.5 22.4 17.5 23.7 47.3 25.1 22.2 37.0 40.3 16.5 18.6 27.5 27.6 21.6 22.1 22.0 11.5 27.8 45.3 42.2 22.7 21.0 26.7 30.0 9.4 7.2 8.5 12.0 7.6 13.4 9.1 8.1 8.7 5.8 10.0 8.7 7.8 11.9 10.4 12.6 6.3 7.2 8.1 19.0 21.3 17.7 17.7 16.5 18.2 23.5 20.2 19.9 18.1 20.4 20.5 7.3 12.8 6.7 5.2 22.3 4.6 11.4 11.3 6.2 11.8 11.2 8.8 6.7 7.2 8.9 9.2 12.5 11.1 23.9 13.5 7.9 13.1 3.7 9.3 8.6 8.4 11.5 7.8 4.1 26.1 4.5 10.0 15.3 9.8 16.5 11.2 9.7 6.5 15.3 10.1 4.7 12.1 18.3 10.0 7.9 8.4 12.8 12.3 1.8 3.7 16.1 7.1 25.7 1.0 6.6 20.5 5.9 11.3 18.6 10.0 16.7 9.3 12.2 8.5 0.0 13.1 8.5 22.5 12.9 10.8 5.8 18.3 20.1 7.2 10.7 13.3 CCND2 ENSG00000118971 "Cyclin D2" P30279 12 4269771-4305353 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 354.3;Granulosa cells: 438.5;Langerhans cells: 255.3;Plasma cells: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 152.4;HBEC3-KT: 136.6;HDLM-2: 238.8;Karpas-707: 287.9;RH-30: 202.7;RPMI-8226: 114.2" "HPA049138, HPA054196" Approved Enhanced Nucleoplasm Yes Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA049138: AB_2680650, HPA054196: AB_2682412" "unprognostic (2.98e-3)" "unprognostic (1.15e-1)" "unprognostic (7.21e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (4.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.01e-3)" "unprognostic (3.16e-2)" "unprognostic (1.66e-2)" "prognostic favorable (2.52e-4)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (8.23e-2)" "unprognostic (4.52e-1)" "prognostic favorable (9.76e-5)" "unprognostic (7.06e-2)" 20.0 52.6 5.4 8.7 12.9 20.3 13.0 0.0 13.5 26.9 0.0 40.8 17.4 26.1 7.5 12.2 22.1 2.7 51.9 14.4 1.1 9.7 1.9 17.2 5.3 9.6 0.2 14.2 24.5 9.9 23.5 12.9 2.7 20.7 10.4 0.7 10.8 9.1 1.8 12.6 25.9 9.8 7.8 19.7 12.7 4.0 0.0 3.2 20.3 0.0 5.1 26.5 19.9 4.5 0.0 0.0 152.4 0.0 10.1 0.4 0.0 0.0 0.0 0.0 0.0 62.8 0.0 0.0 0.4 0.0 0.0 16.2 0.1 136.6 0.0 238.8 2.5 0.7 0.0 0.0 0.0 57.0 12.6 23.8 2.4 0.0 97.0 0.0 0.0 0.8 17.0 287.9 6.8 0.0 0.0 52.8 50.8 0.0 0.0 0.0 202.7 114.2 0.0 8.1 0.0 0.0 0.0 0.0 0.0 89.6 0.0 0.0 4.2 0.0 39.3 0.0 0.0 1.4 60.7 0.0 0.0 32.3 0.0 6.6 0.4 4.7 11.1 0.0 17.1 3.1 16.3 13.8 0.4 1.7 10.4 12.1 1.1 9.4 0.0 1.1 13.6 6.8 5.4 12.9 0.0 13.5 14.4 1.1 9.6 0.2 2.7 7.8 0.0 4.5 23.9 60.9 46.6 10.1 82.9 106.8 23.9 73.4 174.2 7.6 3.4 41.8 354.3 2.8 37.4 12.9 0.0 4.0 128.7 37.5 0.0 3.1 0.8 3.3 110.8 35.7 64.8 37.2 54.1 68.3 2.7 123.6 4.6 3.6 55.8 438.5 19.6 2.2 13.0 3.3 55.2 147.7 12.2 11.9 255.3 3.3 52.5 39.3 39.2 19.7 9.8 170.0 89.6 55.3 4.0 20.7 49.4 124.1 371.2 35.8 34.4 1.4 10.3 6.5 26.3 21.4 112.6 0.8 5.1 50.9 39.6 6.3 122.6 41.5 159.7 8.4 CCPG1 "CPR8, KIAA1254" ENSG00000260916 "Cell cycle progression 1" Q9ULG6 15 55340032-55408510 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 279.2;neutrophil: 296.6" "Group enriched" "Detected in all" 7 "granulocytes: 296.6;monocytes: 84.2" "Cell line enhanced" "Detected in many" "HHSteC: 223.9;Karpas-707: 337.4;U-266/84: 259.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009432, HPA026861" Approved Approved "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Endoplasmic reticulum" "HPA009432: AB_2668242, HPA026861: AB_1846192" "unprognostic (3.14e-2)" "unprognostic (2.94e-2)" "unprognostic (3.03e-1)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (1.40e-2)" "unprognostic (8.34e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-2)" "unprognostic (2.61e-2)" "prognostic unfavorable (5.07e-4)" "prognostic unfavorable (5.02e-5)" "unprognostic (1.15e-1)" "unprognostic (1.71e-2)" "unprognostic (1.72e-2)" 38.9 37.8 24.0 23.7 27.7 63.8 34.1 23.1 28.4 61.1 36.8 33.3 24.3 26.7 36.1 20.1 22.0 53.8 56.2 24.7 26.9 51.5 66.9 39.3 22.2 18.4 17.3 22.9 84.8 73.3 32.3 27.4 17.7 41.0 33.2 48.2 77.1 42.3 53.0 13.5 25.6 33.5 17.2 28.7 47.5 29.6 27.3 12.2 84.4 35.3 24.2 29.9 9.7 22.9 13.9 47.7 10.9 24.4 173.6 59.3 15.5 30.0 56.4 17.2 26.1 14.4 23.5 20.8 99.5 97.5 33.6 18.7 9.5 25.1 14.4 55.5 14.2 28.1 58.4 12.8 223.9 39.6 84.2 49.5 59.8 35.6 34.4 143.3 65.2 0.8 47.7 337.4 55.1 17.9 0.2 19.3 6.5 54.4 11.8 6.2 17.4 84.8 36.1 10.1 14.0 21.5 35.3 19.5 151.4 35.0 31.0 85.1 65.7 50.8 11.1 38.9 20.4 65.2 259.6 13.0 95.6 77.2 41.0 220.8 59.4 279.2 26.8 50.7 22.5 18.1 16.6 20.7 27.6 13.4 13.9 20.0 296.6 25.7 84.2 4.7 23.0 32.9 24.0 27.7 23.1 28.4 24.7 26.9 18.4 17.3 17.7 17.2 27.3 22.9 92.3 115.4 118.1 0.0 44.6 15.4 30.3 99.2 13.6 68.7 40.2 40.1 14.4 50.1 136.5 88.3 93.8 29.3 42.9 43.7 5.9 60.9 136.2 49.6 41.0 60.1 16.7 25.2 0.0 145.3 23.2 78.6 33.1 62.3 39.1 30.0 76.1 96.1 51.0 85.8 0.0 28.8 114.0 55.9 25.2 216.1 56.5 71.7 48.0 0.0 89.8 72.6 38.1 0.0 0.0 67.6 45.1 116.6 180.8 42.6 29.5 36.7 123.8 128.0 52.6 80.2 48.1 43.3 41.1 11.8 16.6 24.6 41.8 70.0 16.2 21.8 CCR1 "CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1" ENSG00000163823 "C-C motif chemokine receptor 1" P32246 3 46201711-46208313 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.5" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 81.2;Hofbauer cells: 117.4;Kupffer cells: 171.9;Macrophages: 74.2;monocytes: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 330.3;RPMI-8226: 158.5;U-266/70: 57.7;U-266/84: 183.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.95e-1)" "unprognostic (2.17e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (4.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.09e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (1.08e-1)" "unprognostic (5.52e-3)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" 21.0 4.7 2.1 42.5 2.3 24.8 4.0 2.4 3.1 2.5 2.6 5.6 7.3 2.5 1.6 3.4 2.8 11.7 2.4 1.9 2.6 4.9 17.2 18.7 10.9 5.2 3.2 2.1 3.1 1.9 0.9 26.4 4.5 1.6 7.3 0.3 2.1 2.6 1.3 0.6 6.6 15.5 4.7 30.8 4.9 1.7 4.9 5.7 1.0 3.3 10.2 16.7 0.7 7.4 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.3 0.7 1.5 0.1 0.4 0.0 3.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 6.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 330.3 0.0 0.2 0.2 13.0 0.0 0.0 0.0 0.1 0.0 158.5 0.0 5.6 0.0 0.0 0.0 0.4 1.3 0.9 0.2 35.5 0.0 0.8 0.0 0.0 0.2 57.7 183.7 0.1 29.1 26.5 0.4 82.5 125.1 25.8 10.5 76.2 50.1 2.9 0.1 8.5 53.9 0.2 0.1 1.4 113.4 84.5 51.3 18.9 0.1 50.6 2.1 2.3 2.4 3.1 1.9 2.6 5.2 3.2 4.5 4.7 4.9 7.4 0.3 3.2 3.0 0.0 2.0 0.9 0.0 0.0 0.6 0.0 0.1 0.5 0.6 0.0 1.3 0.0 0.0 1.3 15.9 0.0 1.9 0.0 0.4 0.1 0.6 1.6 0.0 1.7 0.0 0.0 81.2 2.4 0.0 0.0 3.8 0.0 1.4 1.2 117.4 0.0 0.0 0.0 0.0 171.9 23.5 0.1 0.0 74.2 5.4 9.4 51.5 0.2 7.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 3.2 1.5 0.2 0.0 0.4 0.5 0.0 0.2 0.2 1.7 2.9 6.0 0.0 0.0 0.0 CCR5 "CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22" ENSG00000160791 "C-C motif chemokine receptor 5" P51681 3 46370854-46376206 "CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.0" "Cell type enhanced" "Detected in some" "Kupffer cells: 5.5;Langerhans cells: 32.6;Macrophages: 12.8;T-cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 39.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "JURKAT: 1.4;Karpas-707: 6.8;U-266/84: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (4.32e-3)" "unprognostic (1.94e-3)" "unprognostic (1.89e-3)" "prognostic favorable (7.42e-5)" "unprognostic (1.80e-2)" "prognostic favorable (9.33e-5)" "unprognostic (3.38e-3)" "unprognostic (9.90e-3)" "unprognostic (7.65e-2)" "unprognostic (6.22e-2)" "unprognostic (1.36e-1)" "unprognostic (5.34e-2)" "unprognostic (1.14e-3)" "unprognostic (8.34e-2)" "unprognostic (4.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.42e-2)" 1.8 2.0 0.5 15.0 0.6 1.3 2.4 0.6 0.7 2.1 1.0 3.3 4.1 1.4 1.0 1.4 1.7 5.0 1.1 0.4 0.8 1.0 3.4 7.4 14.4 1.6 0.9 1.7 0.6 0.6 0.4 0.7 1.3 1.9 3.9 0.1 2.9 1.0 0.3 1.1 5.8 3.2 1.2 9.4 6.8 0.8 1.2 4.2 0.8 0.2 9.4 4.8 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 6.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 3.1 0.0 0.0 0.1 0.0 12.0 2.2 0.0 11.0 3.8 39.7 0.5 4.7 16.1 9.5 0.0 0.4 4.1 0.5 6.3 0.0 9.0 8.0 3.2 0.5 0.6 0.6 0.7 0.4 0.8 1.6 0.9 1.3 1.2 1.2 2.4 0.3 0.0 1.7 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.3 1.5 0.0 1.3 0.0 1.4 0.3 4.7 0.0 0.0 0.0 0.0 5.5 32.6 0.0 0.0 12.8 3.6 1.9 1.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 13.1 0.1 0.0 0.1 CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in some" "B-cells: 53.6;Hofbauer cells: 78.6;Kupffer cells: 23.5;Macrophages: 17.5;monocytes: 13.8;Plasma cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.0;naive B-cell: 78.9" "Group enriched" "Detected in many" 25 "B-cells: 78.9;dendritic cells: 23.5;monocytes: 34.5" "Group enriched" "Detected in some" 10 "Daudi: 45.2;Karpas-707: 41.1;U-266/70: 33.1;U-266/84: 49.0;U-698: 12.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: AB_1078450" "unprognostic (9.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.81e-3)" "unprognostic (5.85e-3)" "unprognostic (2.25e-2)" "unprognostic (4.04e-3)" "unprognostic (1.09e-1)" "unprognostic (4.95e-2)" "unprognostic (5.83e-2)" "unprognostic (3.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" 1.6 0.7 0.7 9.7 0.7 2.4 6.7 0.6 1.2 0.5 0.4 2.1 2.0 0.5 0.2 0.4 0.4 1.6 0.4 0.8 0.7 0.3 2.5 1.6 23.2 1.5 1.5 0.2 0.3 0.2 0.1 3.2 2.0 0.5 2.7 0.3 1.1 0.4 0.1 0.2 3.9 1.8 1.0 12.9 2.2 0.4 1.8 2.5 0.3 0.2 23.3 3.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.6 0.2 33.1 49.0 12.3 0.0 2.7 0.0 0.3 11.8 0.9 0.0 20.4 0.0 77.0 0.1 0.1 22.1 78.9 0.0 0.0 0.9 1.8 34.5 23.5 0.1 8.5 0.7 0.7 0.6 1.2 0.8 0.7 1.5 1.5 2.0 1.0 1.8 2.1 0.1 0.0 0.5 0.3 53.6 0.4 0.1 0.0 0.0 0.1 1.8 1.1 0.7 1.5 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 2.2 0.1 0.0 0.6 0.0 1.7 0.0 0.2 0.3 0.4 0.0 0.1 2.5 0.0 0.0 0.3 78.6 0.0 0.0 0.0 0.0 23.5 8.0 1.0 0.0 17.5 0.0 1.9 13.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 39.6 0.0 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 2.2 0.0 0.1 0.1 CD28 ENSG00000178562 "CD28 molecule" P10747 2 203706475-203738912 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 30.8;placenta: 14.8" "Group enriched" "Detected in some" 5 "Hofbauer cells: 34.1;T-cells: 52.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 101.9" "Lineage enriched" "Detected in many" 7 "T-cells: 101.9" "Group enriched" "Detected in some" 14 "Karpas-707: 360.6;RPMI-8226: 173.2;U-266/70: 294.1;U-266/84: 283.7" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "Not detected" "Not detected" HPA070003 Enhanced NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA070003: AB_2686226" "unprognostic (5.54e-2)" "unprognostic (2.16e-4)" "unprognostic (1.90e-3)" "unprognostic (2.49e-3)" "unprognostic (3.44e-2)" "unprognostic (6.07e-5)" "unprognostic (9.09e-2)" "unprognostic (4.66e-2)" "unprognostic (3.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-1)" "unprognostic (1.68e-1)" "unprognostic (5.78e-5)" "unprognostic (4.77e-2)" "unprognostic (2.93e-2)" "unprognostic (7.79e-2)" "unprognostic (8.96e-2)" 4.0 0.3 0.0 14.9 0.1 3.3 0.8 0.1 0.1 1.1 0.9 1.7 1.1 0.7 0.3 0.9 0.5 4.1 0.6 0.1 0.1 0.5 1.3 1.9 28.0 0.1 0.0 0.3 0.5 0.2 0.1 14.8 0.1 1.0 1.9 0.1 0.6 0.8 0.3 0.3 3.0 1.4 0.1 7.2 2.5 0.7 0.2 30.8 0.5 0.1 18.6 4.6 0.3 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.1 0.7 2.0 0.0 360.6 0.2 0.0 19.9 0.0 0.1 0.0 0.0 0.1 0.3 173.2 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.1 0.3 294.1 283.7 2.9 0.3 0.1 0.0 1.7 0.6 1.0 8.3 0.5 50.6 0.3 54.5 26.1 0.1 0.3 48.1 18.6 13.8 0.2 0.5 0.2 101.9 14.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.5 0.0 1.3 0.0 2.4 2.9 0.1 0.0 0.6 0.0 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.2 3.2 0.1 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.3 1.0 2.0 0.1 1.3 0.0 0.0 0.1 34.1 0.0 0.0 0.0 0.0 0.8 5.3 0.2 0.0 4.4 0.0 1.0 1.5 0.0 2.1 0.0 0.1 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.1 0.2 1.6 0.1 52.6 0.0 0.0 0.0 CDC20B FLJ37927 ENSG00000164287 "Cell division cycle 20B" Q86Y33 5 55112971-55173177 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 2.1;kidney: 1.1;testis: 2.6" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 18.8;Ionocytes: 12.2;Respiratory ciliated cells: 24.5" "Cancer enhanced" "Detected in some" "endometrial cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA053900 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 2: Karpas-707 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA053900: AB_2682299" "unprognostic (7.39e-3)" "unprognostic (1.02e-1)" "unprognostic (8.19e-2)" "unprognostic (1.78e-3)" "unprognostic (9.94e-2)" "unprognostic (1.59e-2)" "unprognostic (3.12e-1)" "unprognostic (1.59e-2)" "unprognostic (5.60e-2)" "unprognostic (7.84e-3)" "unprognostic (2.83e-2)" "unprognostic (3.06e-1)" "unprognostic (5.15e-4)" "unprognostic (1.99e-2)" "unprognostic (2.27e-1)" "unprognostic (6.10e-2)" "unprognostic (1.29e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 2.1 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.2 0.0 0.3 2.4 1.2 0.0 0.9 2.3 0.5 0.0 2.1 0.0 0.0 0.1 0.2 1.6 0.0 0.1 0.3 18.8 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.7 3.6 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 2.5 12.2 0.6 4.1 0.0 0.0 0.7 1.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 3.7 0.9 2.7 0.8 24.5 0.0 0.0 0.5 0.5 1.3 0.8 0.7 0.1 0.1 0.3 0.1 0.7 0.1 CDK14 "PFTAIRE1, PFTK1" ENSG00000058091 "Cyclin dependent kinase 14" O94921 7 90466424-91210590 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 545.4;Horizontal cells: 173.3;Inhibitory neurons: 426.8;Oligodendrocyte precursor cells: 320.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 9.0;memory B-cell: 8.5;naive B-cell: 4.8;neutrophil: 4.8" "Group enriched" "Detected in many" 10 "B-cells: 8.5;granulocytes: 9.0" "Cell line enhanced" "Detected in many" "Karpas-707: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015267 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA015267: AB_1855249" "prognostic favorable (5.86e-4)" "unprognostic (3.96e-1)" "unprognostic (1.91e-2)" "unprognostic (2.09e-3)" "unprognostic (1.18e-1)" "unprognostic (3.45e-1)" "unprognostic (1.72e-1)" "unprognostic (4.48e-2)" "unprognostic (3.60e-2)" "unprognostic (3.09e-2)" "unprognostic (2.77e-3)" "unprognostic (2.91e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (7.79e-4)" "unprognostic (2.46e-1)" "unprognostic (2.86e-1)" "unprognostic (4.39e-3)" 10.1 4.4 9.7 7.8 12.8 7.1 8.6 11.6 31.2 10.1 0.0 5.9 2.7 8.5 3.1 3.1 12.2 12.2 11.9 18.5 7.9 20.7 13.4 9.6 12.4 7.8 17.9 14.5 15.1 3.0 9.2 6.1 7.8 11.2 3.3 17.4 8.3 6.7 4.6 2.5 3.8 7.6 6.4 8.2 8.0 7.9 19.2 5.5 13.3 7.2 12.9 5.7 5.2 20.5 18.0 0.2 35.0 4.5 31.9 32.0 8.0 14.7 14.0 8.8 9.5 0.4 8.6 58.9 1.8 14.6 13.1 5.2 1.8 20.7 16.9 0.1 8.3 0.0 11.2 0.4 14.7 18.3 0.3 22.7 5.3 26.5 9.4 14.7 11.6 0.4 0.3 78.4 18.4 0.1 0.1 7.3 21.8 0.1 9.6 49.3 47.4 50.2 4.6 4.9 7.7 21.9 37.3 0.2 0.7 15.4 4.7 9.2 28.4 37.8 48.5 32.1 23.0 43.1 36.3 41.9 14.6 23.8 37.9 9.0 0.3 0.5 0.0 0.6 0.0 8.5 0.0 0.0 0.8 4.8 0.0 0.0 4.8 0.1 0.5 0.1 0.2 0.5 9.7 12.8 11.6 31.2 18.5 7.9 7.8 17.9 7.8 6.4 19.2 20.5 11.0 19.2 5.1 118.2 37.4 0.8 7.7 6.0 2.2 6.9 7.0 8.9 18.3 12.8 9.1 11.0 0.0 0.2 0.2 0.4 7.9 9.8 53.9 1.7 13.4 2.8 1.8 4.0 545.4 6.7 0.1 16.1 4.1 1.5 0.0 11.2 1.4 11.3 3.7 173.3 426.8 0.3 4.1 3.4 4.9 46.4 15.5 7.0 5.4 66.5 1.7 9.4 0.0 320.7 32.9 13.4 1.3 15.8 78.1 12.8 0.1 22.7 3.9 9.7 0.0 6.3 15.9 5.4 6.6 1.2 1.3 0.0 1.9 6.5 0.3 4.2 CDKN1B "KIP1, P27KIP1" ENSG00000111276 "Cyclin dependent kinase inhibitor 1B" P46527 12 12715058-12722369 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 182.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003691, CAB021888, HPA059086" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "CAB003691: AB_425362, CAB021888: , HPA059086: AB_2683900" "unprognostic (5.67e-2)" "unprognostic (9.76e-2)" "prognostic favorable (5.15e-4)" "unprognostic (6.90e-3)" "unprognostic (5.84e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (4.04e-2)" "unprognostic (1.11e-1)" "unprognostic (2.85e-3)" "unprognostic (9.23e-3)" "unprognostic (2.96e-1)" "prognostic unfavorable (8.39e-4)" "unprognostic (1.23e-1)" "unprognostic (8.68e-2)" "unprognostic (2.88e-1)" "unprognostic (1.15e-1)" 53.4 44.7 53.6 40.1 70.6 68.1 50.2 73.4 81.3 55.3 43.1 43.9 44.5 41.0 24.5 29.1 47.3 24.6 32.9 47.9 58.9 30.2 35.2 38.9 55.3 58.6 58.3 66.1 23.9 34.4 24.4 41.0 61.2 35.9 32.5 55.3 36.3 33.4 81.4 45.4 40.7 24.8 55.1 55.1 30.0 25.8 58.3 71.8 33.7 63.4 39.9 32.0 44.5 91.2 37.1 16.6 94.5 16.6 32.0 18.0 46.1 31.5 53.8 46.0 56.4 47.7 40.4 0.3 12.5 19.6 16.6 34.2 44.9 16.7 41.1 62.4 31.5 28.8 46.5 53.2 42.5 24.5 18.6 19.8 35.3 15.2 44.0 107.8 27.8 54.5 31.5 101.6 16.6 45.9 32.7 35.3 38.0 32.1 16.8 25.2 30.9 63.1 22.5 38.6 35.6 58.4 48.9 34.8 65.8 33.7 18.6 54.6 19.1 22.6 34.9 20.7 33.3 86.1 59.4 33.2 28.2 36.6 22.5 6.2 3.8 8.6 5.9 3.5 6.1 6.8 7.7 7.2 3.6 5.0 8.0 6.1 20.9 7.3 5.5 3.9 12.3 4.0 53.6 70.6 73.4 81.3 47.9 58.9 58.6 58.3 61.2 55.1 58.3 91.2 64.2 44.8 29.3 6.2 126.2 52.6 20.7 21.0 115.5 45.6 39.5 30.1 39.1 21.5 27.1 9.2 27.1 42.9 92.5 32.3 15.6 10.8 70.0 31.2 35.8 51.1 45.7 70.5 8.1 9.3 47.6 39.3 25.5 34.3 31.0 21.3 47.2 30.7 26.8 10.1 13.4 41.4 24.4 55.3 66.0 67.7 55.9 65.1 74.7 23.4 31.6 182.9 60.8 6.0 29.5 10.1 21.3 26.7 121.2 30.3 33.4 16.9 36.4 29.4 92.1 20.2 53.5 7.7 10.8 102.3 52.6 39.0 166.1 20.9 41.9 22.7 CENPU "CENP-50, CENP-U, KLIP1, MLF1IP, PBIP1" ENSG00000151725 "Centromere protein U" Q71F23 4 184694085-184734130 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.6;testis: 29.5" "Cell type enhanced" "Detected in many" "Early spermatids: 489.7;Late spermatids: 900.3;Spermatocytes: 490.2;Spermatogonia: 215.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 20.7;eosinophil: 14.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 20.7" "Cell line enhanced" "Detected in many" "Karpas-707: 157.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022048 Supported "Nucleoplasm,Centriolar satellite" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centriolar satellite" "HPA022048: AB_1853985" "unprognostic (1.47e-1)" "unprognostic (9.88e-2)" "unprognostic (5.02e-2)" "unprognostic (2.37e-1)" "unprognostic (9.45e-2)" "unprognostic (4.97e-2)" "unprognostic (4.39e-3)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.67e-3)" "unprognostic (3.34e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.11e-9)" "unprognostic (2.19e-2)" "unprognostic (7.40e-3)" "unprognostic (4.46e-2)" "unprognostic (2.74e-1)" 1.5 1.1 0.1 5.4 0.3 62.6 5.7 0.6 0.3 2.4 0.1 7.8 5.1 1.5 0.7 10.5 0.9 1.1 1.5 0.2 0.2 0.7 3.7 1.7 16.2 0.2 0.2 0.6 1.0 1.4 0.2 4.8 0.6 1.3 8.0 1.5 2.7 0.4 0.9 15.3 5.4 2.7 0.2 2.3 3.7 29.5 0.4 12.8 1.3 0.1 13.6 2.1 3.9 0.5 57.8 17.1 67.9 35.8 4.3 6.4 37.6 40.8 19.4 32.2 21.2 24.8 32.1 45.9 3.8 18.7 20.2 23.0 52.4 33.2 30.6 23.4 23.0 50.4 17.5 12.6 0.7 71.1 29.3 2.7 2.1 33.3 8.4 9.4 32.1 53.9 44.1 157.3 51.1 38.2 111.4 53.0 33.8 12.7 21.5 74.5 24.3 15.6 17.1 26.7 52.0 49.0 31.4 39.4 23.9 25.0 44.1 50.2 20.9 23.8 31.3 23.5 39.7 26.5 29.5 37.6 37.2 55.4 94.5 20.7 0.7 14.2 0.5 2.0 0.4 0.9 0.7 0.8 0.4 0.9 0.6 0.8 0.1 3.5 2.8 1.9 2.5 0.6 0.1 0.3 0.6 0.3 0.2 0.2 0.2 0.2 0.6 0.2 0.4 0.5 1.4 9.6 3.2 0.3 6.5 13.9 6.0 11.5 3.4 0.9 11.5 7.9 2.3 4.3 8.7 1.8 0.0 31.5 5.4 8.9 3.9 4.8 489.7 9.5 4.0 3.8 0.0 115.7 0.4 2.5 48.4 7.3 9.2 6.6 8.9 27.1 1.1 0.9 21.6 0.0 0.4 10.0 10.2 5.1 7.3 900.3 9.0 15.3 0.0 1.0 5.3 0.2 4.1 0.5 1.9 3.0 1.0 6.8 28.3 2.6 0.9 0.7 5.6 1.4 19.7 2.0 7.2 490.2 215.1 29.1 21.5 7.5 6.3 4.4 18.1 11.6 CEP120 "CCDC100, FLJ36090" ENSG00000168944 "Centrosomal protein 120" Q8N960 5 123344890-123423592 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028823, HPA051556" Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" "HPA028823: AB_10601355, HPA051556: AB_2681533" "unprognostic (3.65e-1)" "unprognostic (9.94e-2)" "unprognostic (3.69e-2)" "unprognostic (1.49e-1)" "unprognostic (1.10e-1)" "unprognostic (2.97e-2)" "unprognostic (4.41e-1)" "unprognostic (1.15e-1)" "unprognostic (2.83e-2)" "unprognostic (5.74e-2)" "unprognostic (1.82e-2)" "unprognostic (1.51e-1)" "unprognostic (4.94e-3)" "unprognostic (1.05e-1)" "unprognostic (1.69e-1)" "unprognostic (9.44e-3)" "unprognostic (1.58e-1)" 8.3 7.1 1.6 7.1 1.9 3.0 7.2 2.0 2.6 8.8 2.1 7.2 4.9 9.3 3.6 4.5 9.4 7.2 6.2 2.1 2.1 7.0 7.9 7.3 9.6 2.0 2.1 15.5 6.3 7.6 6.5 6.0 1.9 6.9 5.1 11.6 5.2 7.7 4.4 4.1 7.3 8.0 1.7 9.1 5.1 13.8 1.9 14.1 8.2 6.2 10.9 6.7 6.1 2.3 8.5 7.7 10.6 12.7 11.9 13.7 9.1 11.4 14.1 10.8 19.3 5.7 7.2 11.9 9.7 6.7 17.6 5.3 9.2 10.0 18.5 27.1 4.1 6.2 2.7 6.9 12.8 7.0 11.1 11.5 12.3 14.8 19.3 9.2 9.7 9.8 6.0 20.5 12.6 3.0 13.3 2.8 5.8 3.8 7.1 7.2 15.5 8.9 5.8 2.9 11.3 8.1 9.1 4.0 13.8 12.4 5.8 16.3 8.3 11.7 9.5 5.8 13.7 12.4 11.5 8.3 10.8 14.2 12.3 0.8 0.2 0.6 0.4 0.4 0.5 0.7 1.0 0.7 0.3 0.3 0.6 1.0 0.1 0.3 0.1 0.0 1.7 0.4 1.6 1.9 2.0 2.6 2.1 2.1 2.0 2.1 1.9 1.7 1.9 2.3 15.1 12.8 10.3 8.8 24.5 5.9 4.1 5.0 15.4 10.2 6.3 4.8 10.0 1.5 10.3 7.3 29.2 4.3 12.4 4.2 1.9 2.8 9.4 12.4 7.8 10.8 2.4 7.2 22.8 4.7 4.3 10.8 9.7 5.7 2.5 20.9 4.6 7.2 5.6 8.4 28.2 3.9 4.1 12.0 4.3 6.4 11.8 9.9 8.8 29.0 9.4 7.6 7.2 19.1 24.2 4.2 3.1 13.9 19.1 3.1 7.1 3.3 26.2 17.4 6.6 10.3 8.9 17.4 9.9 6.3 1.8 2.3 23.0 8.2 3.9 3.2 CHD2 "DKFZp547I1315, DKFZp686E01200, DKFZp781D1727, FLJ38614" ENSG00000173575 "Chromodomain helicase DNA binding protein 2" O14647 15 92900189-93027996 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060744, HPA060960" Enhanced Enhanced Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA060744: AB_2684353, HPA060960: AB_2684398" "unprognostic (1.65e-2)" "unprognostic (2.43e-1)" "unprognostic (2.14e-2)" "unprognostic (5.98e-2)" "unprognostic (2.12e-2)" "unprognostic (3.10e-2)" "unprognostic (2.67e-2)" "unprognostic (7.85e-2)" "unprognostic (7.51e-3)" "unprognostic (1.14e-1)" "unprognostic (2.84e-1)" "unprognostic (1.79e-2)" "unprognostic (4.64e-2)" "unprognostic (1.16e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-1)" "unprognostic (1.70e-2)" 13.9 12.3 22.7 20.7 25.5 73.5 20.4 42.0 32.7 15.7 32.0 15.2 14.8 19.4 29.1 14.6 16.2 15.6 12.0 21.3 24.7 16.9 15.4 21.6 26.4 29.0 23.3 26.1 19.6 18.2 16.6 20.5 24.5 20.4 14.8 30.8 21.2 13.4 17.4 18.8 18.7 13.3 22.1 23.3 17.7 20.8 25.9 27.0 26.3 14.7 25.4 13.7 16.1 27.6 21.3 11.6 30.6 13.6 17.9 45.3 23.0 19.4 20.0 13.0 16.1 14.5 27.4 5.2 16.1 17.3 22.1 31.1 17.6 19.5 18.0 0.1 10.6 25.3 26.1 12.9 24.6 27.1 19.0 28.7 23.0 15.5 31.1 26.8 22.4 36.7 26.8 57.1 19.9 13.1 14.2 14.0 19.5 10.5 12.6 19.9 27.6 28.4 13.3 28.5 16.8 18.1 34.2 12.3 25.9 30.6 14.1 22.6 36.2 10.7 13.9 9.3 12.8 53.4 23.2 21.6 15.9 15.9 9.4 35.9 10.8 27.7 22.1 6.6 21.8 48.7 21.5 20.5 7.4 39.6 30.1 22.1 53.7 20.6 13.4 27.9 24.9 10.9 22.7 25.5 42.0 32.7 21.3 24.7 29.0 23.3 24.5 22.1 25.9 27.6 59.3 70.5 176.3 182.2 137.8 164.3 112.3 102.3 153.7 71.4 62.6 46.5 42.3 37.1 137.3 46.0 91.8 30.7 116.3 59.6 3.9 36.1 56.5 96.9 61.7 58.6 59.3 65.4 161.5 38.3 28.5 64.5 96.4 189.8 99.3 70.7 25.0 34.9 24.8 57.2 146.2 54.9 91.6 55.1 297.4 39.2 34.8 89.5 96.0 119.9 50.7 34.2 48.4 140.8 155.9 64.2 61.6 37.6 133.0 110.0 39.9 11.5 93.9 82.2 32.9 52.7 64.4 15.3 14.7 125.2 180.7 60.5 153.2 42.9 51.5 143.6 CHIC1 BRX ENSG00000204116 "Cysteine rich hydrophobic domain 1" Q5VXU3 X 73563200-73687102 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 47.0;Excitatory neurons: 62.7;Inhibitory neurons: 59.6;Microglial cells: 29.0;Oligodendrocyte precursor cells: 66.9;Oligodendrocytes: 76.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA052062" Uncertain Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles, Vesicles" Cytosol "HPA026782: AB_1846654, HPA052062: AB_2681714" "unprognostic (9.85e-3)" "unprognostic (3.91e-2)" "unprognostic (3.10e-2)" "unprognostic (9.95e-2)" "unprognostic (6.22e-2)" "unprognostic (1.91e-1)" "unprognostic (1.57e-1)" "unprognostic (1.36e-2)" "unprognostic (2.43e-1)" "unprognostic (1.25e-1)" "unprognostic (4.42e-3)" "unprognostic (2.65e-1)" "prognostic favorable (2.75e-4)" "unprognostic (1.37e-2)" "unprognostic (2.19e-1)" "unprognostic (3.51e-1)" "unprognostic (2.76e-2)" 2.9 7.0 4.4 3.0 4.8 0.6 3.7 4.6 8.5 7.1 2.4 5.2 2.3 5.6 3.8 2.4 4.2 4.6 5.4 5.7 6.1 6.3 1.5 2.7 3.9 5.9 4.6 5.7 2.2 5.9 5.6 2.1 6.0 4.8 4.2 5.4 2.8 5.1 2.6 3.0 3.4 5.4 4.9 4.1 2.5 1.5 5.8 2.8 6.5 5.2 3.5 4.2 3.4 5.1 4.6 4.7 2.3 3.0 6.5 8.7 0.0 5.1 6.8 4.1 4.9 3.1 5.8 2.1 6.9 4.6 8.1 1.4 3.3 2.5 9.0 5.3 4.1 3.2 4.0 0.0 4.2 0.0 6.0 6.1 2.9 7.7 4.1 5.2 5.9 2.1 0.8 20.3 8.1 0.7 1.9 0.0 7.3 0.0 4.6 1.8 5.9 1.3 5.1 2.3 1.3 1.9 5.8 2.7 6.3 3.9 2.3 1.3 6.9 4.7 4.6 9.4 3.1 5.7 15.3 0.0 6.9 3.4 3.7 0.2 0.0 0.0 0.4 0.0 0.7 0.2 0.3 0.4 0.0 0.2 0.3 0.4 0.0 0.3 0.0 0.0 0.3 0.1 4.4 4.8 4.6 8.5 5.7 6.1 5.9 4.6 6.0 4.9 5.8 5.1 8.3 3.2 9.1 47.0 9.4 2.7 4.6 2.7 4.6 10.0 4.2 3.6 12.7 5.7 4.1 3.7 6.2 0.2 7.5 2.1 0.0 3.5 4.1 10.9 5.6 9.4 0.0 4.4 62.7 3.5 0.0 8.2 1.5 7.3 5.1 5.3 5.3 1.6 1.6 13.5 59.6 7.5 2.0 2.2 1.8 1.8 3.1 2.3 5.4 29.0 1.6 5.7 8.2 66.9 76.1 2.4 6.1 9.1 6.7 5.4 1.4 11.4 3.9 7.5 0.0 8.3 5.0 2.0 2.4 2.4 4.5 0.0 8.8 5.9 3.4 4.6 CHSY1 "CSS1, KIAA0990" ENSG00000131873 "Chondroitin sulfate synthase 1" Q86X52 15 101175727-101252048 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (7.28e-2)" "unprognostic (6.39e-2)" "unprognostic (9.24e-2)" "unprognostic (1.55e-1)" "unprognostic (7.60e-2)" "unprognostic (9.51e-3)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (1.77e-1)" "unprognostic (1.32e-2)" "unprognostic (5.97e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.33e-5)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" 27.5 18.6 10.3 18.5 9.8 23.0 21.7 9.0 11.8 19.5 14.4 7.7 6.0 17.3 9.5 10.8 14.9 22.7 20.1 9.2 10.3 13.7 10.0 23.6 11.6 14.2 13.8 19.7 7.3 7.4 8.5 46.7 11.9 14.4 8.2 7.0 10.1 11.4 6.5 15.0 7.7 20.0 11.5 13.9 10.4 8.7 12.5 10.5 10.0 7.4 10.3 34.8 14.0 9.8 9.1 11.2 36.8 18.7 18.9 25.0 24.5 21.8 19.2 25.8 26.2 9.7 7.1 22.0 12.7 36.3 16.8 24.7 24.5 27.7 28.2 24.6 12.4 43.4 12.2 11.4 23.3 66.9 42.9 23.2 22.8 22.3 20.1 29.3 30.8 9.7 16.2 216.3 19.7 7.9 9.2 46.3 42.5 17.7 7.9 20.6 36.9 32.8 18.1 17.7 6.4 34.6 23.0 11.1 40.8 29.8 12.6 81.6 26.2 41.9 24.1 20.0 46.5 38.2 94.5 12.7 32.5 62.2 32.0 0.0 1.3 2.9 1.5 0.8 1.7 0.9 0.9 1.6 0.8 1.0 0.5 1.0 4.9 0.7 0.9 0.5 1.8 0.6 10.3 9.8 9.0 11.8 9.2 10.3 14.2 13.8 11.9 11.5 12.5 9.8 55.0 0.0 15.7 27.7 11.4 57.9 20.7 10.1 20.5 10.7 41.9 29.8 9.3 5.7 9.4 16.5 6.2 6.1 14.6 1.6 1.9 5.3 1.2 10.0 33.4 45.8 3.0 12.0 34.2 2.2 28.8 40.0 5.1 13.8 25.9 51.9 60.0 5.4 16.6 38.7 36.1 3.6 10.2 17.8 37.1 2.5 55.0 41.2 26.6 59.0 10.2 9.2 10.3 21.1 24.2 5.5 2.5 47.0 9.3 19.3 1.2 2.4 8.1 7.5 46.0 47.9 53.5 3.9 7.5 10.5 62.5 13.8 15.2 23.0 3.9 10.2 CIART "BC017397, C1orf51, CHRONO" ENSG00000159208 "Circadian associated repressor of transcription" Q8N365 1 150282543-150287093 "Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 30.7;Bipolar cells: 43.1;Cone photoreceptor cells: 102.2;Muller glia cells: 28.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.2;memory CD4 T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 26.4;Karpas-707: 36.8;U-266/84: 29.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027515, HPA054349" Enhanced Approved Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA027515: AB_10600757, HPA054349: AB_2682457" "unprognostic (1.77e-1)" "unprognostic (5.63e-2)" "unprognostic (4.15e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (4.42e-1)" "unprognostic (5.99e-3)" "unprognostic (2.29e-2)" "unprognostic (1.47e-1)" "unprognostic (1.31e-1)" "unprognostic (1.89e-1)" "unprognostic (4.54e-2)" "unprognostic (1.01e-2)" "unprognostic (1.16e-1)" "unprognostic (1.45e-1)" "unprognostic (1.64e-1)" "unprognostic (2.34e-2)" 6.9 13.5 15.1 3.1 22.2 0.4 7.5 20.1 19.9 6.7 17.8 22.8 3.3 9.6 9.3 8.2 10.2 4.5 29.4 15.4 15.8 10.1 13.7 5.8 2.6 13.3 14.8 10.1 5.0 32.0 17.7 2.7 13.7 9.4 2.8 22.2 17.8 23.9 54.2 40.5 6.4 9.0 13.2 2.8 13.8 9.8 16.7 2.0 19.0 46.4 3.5 11.8 8.3 14.1 0.2 1.0 6.7 3.4 3.0 1.3 6.6 4.8 11.8 6.2 8.2 1.8 26.4 0.1 8.3 10.4 14.1 4.5 0.2 4.8 9.3 0.1 0.6 0.2 0.4 0.1 10.5 1.6 3.7 4.0 7.1 15.8 3.2 14.4 1.2 0.1 0.2 36.8 3.6 21.8 0.0 0.8 8.9 4.9 19.9 1.1 0.0 0.3 6.2 1.0 4.1 1.5 7.9 0.7 14.6 1.7 6.7 0.6 2.1 17.3 0.2 0.7 10.5 8.2 29.6 0.2 16.0 0.1 10.5 0.0 0.0 0.0 0.1 0.0 1.2 0.0 1.4 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.1 15.1 22.2 20.1 19.9 15.4 15.8 13.3 14.8 13.7 13.2 16.7 14.1 2.8 0.0 1.5 5.5 0.6 0.0 5.5 0.0 30.7 43.1 5.5 7.7 7.3 4.3 1.3 0.0 102.2 0.2 0.6 0.4 9.8 3.2 0.6 2.9 2.5 3.0 2.4 0.0 3.1 1.5 0.1 4.8 3.6 2.1 0.0 3.5 0.7 4.2 1.3 6.7 3.9 0.9 0.0 0.3 0.0 1.4 5.3 1.9 0.0 0.0 1.0 28.2 0.0 1.5 1.1 4.1 1.2 9.4 0.2 4.4 7.7 3.9 0.7 18.1 0.0 4.6 4.5 7.2 10.9 11.2 0.0 0.0 0.9 4.1 0.7 2.7 CIC KIAA0306 ENSG00000079432 "Capicua transcriptional repressor" Q96RK0 19 42268537-42295797 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026388, HPA044341, HPA064725" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Vesicles "CAB026388: , HPA044341: AB_2678901, HPA064725: AB_2685335" "unprognostic (2.02e-2)" "unprognostic (4.08e-1)" "unprognostic (1.41e-2)" "unprognostic (3.54e-3)" "unprognostic (3.67e-1)" "unprognostic (4.17e-3)" "unprognostic (1.49e-1)" "unprognostic (2.06e-1)" "unprognostic (4.87e-1)" "unprognostic (1.85e-2)" "unprognostic (1.72e-3)" "unprognostic (3.10e-1)" "unprognostic (4.23e-2)" "unprognostic (1.00e-1)" "unprognostic (2.38e-1)" "unprognostic (1.88e-2)" "unprognostic (1.56e-1)" 41.9 41.5 43.3 23.4 36.1 31.8 42.7 40.7 47.4 53.8 2.3 45.6 15.6 62.3 8.7 34.3 49.1 16.1 35.4 36.3 27.7 41.7 44.6 40.8 24.2 39.5 27.8 70.1 39.4 12.2 58.7 12.6 35.7 40.5 5.8 13.5 35.4 18.7 45.2 47.2 36.9 16.0 17.4 46.9 38.6 74.6 29.4 21.0 44.3 15.3 13.5 39.6 37.5 32.5 31.8 56.7 26.4 34.4 16.6 30.7 10.7 22.8 22.5 22.9 20.9 18.5 21.4 26.7 20.8 21.8 19.6 16.6 14.6 38.9 7.6 61.9 19.6 22.2 44.7 23.0 20.1 11.8 50.9 36.7 25.5 24.4 15.5 24.8 19.2 15.9 21.8 52.5 13.3 31.9 25.1 25.6 16.2 12.6 5.8 21.5 21.2 14.3 20.5 25.3 33.6 27.1 23.7 15.7 21.6 8.3 18.3 25.8 27.5 52.0 43.7 15.9 33.2 41.0 29.8 18.1 37.9 19.4 32.6 0.0 0.5 0.1 0.7 0.8 0.5 0.5 0.3 0.5 0.5 0.6 0.2 0.4 1.1 0.2 0.6 0.6 0.1 0.6 43.3 36.1 40.7 47.4 36.3 27.7 39.5 27.8 35.7 17.4 29.4 32.5 27.8 0.0 3.0 15.7 13.7 25.9 12.8 16.2 27.9 38.3 20.7 16.9 7.8 21.5 7.1 9.2 20.9 6.9 9.1 14.2 3.9 13.4 5.1 14.6 14.9 20.3 14.8 8.4 8.0 15.3 5.1 11.2 17.9 22.3 12.0 11.1 13.9 19.2 11.9 42.1 9.0 10.1 10.2 18.0 23.6 3.3 21.8 15.3 24.9 7.5 13.0 18.4 8.2 4.0 10.3 16.9 11.2 18.0 10.4 11.3 10.6 6.2 8.0 18.8 26.3 19.9 17.6 19.4 20.2 16.5 19.5 13.0 13.2 14.2 10.6 11.9 CLCN3 "ClC-3, CLC3" ENSG00000109572 "Chloride voltage-gated channel 3" P51790 4 169612633-169723673 "Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044723 Approved Supported Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA044723: AB_10959733" "unprognostic (1.92e-1)" "unprognostic (3.92e-2)" "unprognostic (1.95e-3)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (2.25e-1)" "unprognostic (3.32e-1)" "unprognostic (1.79e-1)" "unprognostic (5.40e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.49e-2)" "unprognostic (2.49e-1)" "unprognostic (1.45e-1)" "unprognostic (6.38e-3)" 21.1 34.5 20.1 20.6 28.7 12.3 31.9 29.1 30.2 23.9 20.5 47.5 30.1 18.7 29.4 40.7 26.4 38.0 35.3 22.8 30.5 36.4 25.7 21.2 17.3 32.3 41.0 23.1 41.0 37.2 18.2 24.1 32.1 32.7 52.6 78.3 78.0 21.8 24.7 29.1 29.8 17.8 32.3 16.7 41.2 33.3 26.5 21.0 37.0 22.1 24.5 37.4 17.1 42.0 32.6 33.2 48.7 62.1 96.1 80.8 24.0 42.9 53.5 28.3 34.3 23.7 72.2 40.0 26.1 35.9 32.7 27.2 61.2 26.6 46.9 35.9 24.4 33.8 50.6 27.3 65.8 41.0 54.2 56.6 59.7 50.5 49.5 117.4 51.7 55.2 85.1 88.0 49.7 11.8 56.2 9.4 20.0 56.2 22.4 25.0 21.5 31.6 58.1 66.6 51.9 51.5 38.4 40.9 66.9 39.3 27.9 19.2 43.5 22.5 25.3 36.5 33.7 39.3 64.3 35.5 67.6 15.4 60.8 3.8 4.1 2.9 5.0 4.8 6.5 5.0 3.7 4.7 5.7 3.8 5.7 5.2 2.9 4.5 4.0 7.1 4.7 4.7 20.1 28.7 29.1 30.2 22.8 30.5 32.3 41.0 32.1 32.3 26.5 42.0 35.5 32.1 26.2 58.8 30.7 11.3 25.7 21.5 20.5 90.3 54.6 27.9 66.5 42.9 25.3 62.5 131.3 23.8 23.1 118.3 7.9 37.2 88.1 46.9 35.9 35.2 66.9 83.1 102.4 44.3 18.7 29.5 51.5 51.8 113.0 32.3 38.6 39.3 18.6 60.6 126.1 64.2 20.3 32.9 9.8 67.4 24.5 47.8 32.0 44.0 17.1 136.7 28.8 139.7 141.5 31.9 55.3 21.1 21.4 45.3 37.1 17.9 67.8 115.1 6.6 34.6 21.5 17.2 15.5 42.8 26.1 71.1 21.0 67.0 65.4 34.0 CLEC7A "CD369, CLECSF12, dectin-1, hDectin-1, SCARE2" ENSG00000172243 "C-type lectin domain containing 7A" Q9BXN2 12 10116777-10130258 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 84.0;lung: 30.9;lymphoid tissue: 44.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.2;Kupffer cells: 415.2;Langerhans cells: 291.5;Macrophages: 255.5;monocytes: 186.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 249.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 16 "Karpas-707: 192.2;U-266/84: 168.1" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.79e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.03e-2)" "unprognostic (5.49e-2)" "unprognostic (5.19e-2)" "unprognostic (5.88e-3)" "unprognostic (2.10e-1)" "unprognostic (9.87e-2)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.83e-2)" "unprognostic (3.89e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" 9.9 5.9 2.2 44.5 2.0 84.0 4.5 2.6 3.7 3.5 3.3 7.5 5.6 3.2 3.7 9.7 5.8 11.1 5.7 1.9 3.3 3.5 11.0 30.9 14.4 5.0 2.7 2.4 2.9 2.0 2.7 7.3 4.0 3.3 7.3 1.7 7.3 3.2 1.3 3.8 8.6 8.7 3.6 34.2 4.6 1.5 3.8 10.0 2.6 2.0 11.9 9.1 4.8 6.1 0.3 0.4 0.1 0.2 0.0 0.0 1.1 0.0 0.5 0.2 0.1 0.1 0.4 0.1 0.1 0.0 1.1 0.6 0.0 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.9 0.7 0.1 0.8 0.1 0.0 0.2 0.1 0.2 0.0 192.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 4.3 0.0 5.2 0.3 0.2 0.3 0.6 0.0 1.4 0.4 0.1 0.3 0.1 0.2 0.2 0.2 11.4 168.1 0.1 0.3 1.0 0.2 1.4 122.9 2.2 0.3 137.2 0.5 0.3 0.3 0.2 60.6 0.3 0.3 0.2 249.6 0.4 148.1 1.0 0.4 40.4 2.2 2.0 2.6 3.7 1.9 3.3 5.0 2.7 4.0 3.6 3.8 6.1 2.0 12.8 15.1 0.3 5.9 3.7 0.2 0.9 8.6 0.0 3.1 2.8 0.9 0.0 9.7 0.0 0.0 1.5 2.1 0.2 0.0 0.1 1.7 0.2 0.1 9.3 0.0 0.0 0.1 0.0 14.1 2.4 0.0 0.1 6.3 0.0 6.1 2.1 87.2 0.0 0.1 0.0 4.1 415.2 291.5 2.2 0.3 255.5 3.6 27.2 186.1 0.0 8.2 0.0 0.0 0.0 1.1 0.0 1.1 0.1 0.0 1.3 2.4 0.4 13.1 1.1 1.0 0.1 0.5 13.2 3.0 5.3 4.1 0.0 0.0 0.5 CLK1 ENSG00000013441 "CDC like kinase 1" P49759 2 200853009-200864744 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033141, HPA062405" Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear membrane" "CAB033141: AB_1121713, HPA062405: AB_2684753" "unprognostic (9.79e-2)" "unprognostic (2.05e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (9.19e-2)" "unprognostic (4.50e-3)" "unprognostic (1.52e-1)" "unprognostic (2.77e-3)" "unprognostic (1.78e-2)" "unprognostic (2.09e-2)" "unprognostic (1.09e-2)" "unprognostic (5.63e-3)" "unprognostic (2.03e-3)" "unprognostic (9.66e-2)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "prognostic favorable (2.28e-4)" 89.6 82.7 132.9 25.4 137.1 178.0 72.2 140.9 201.6 118.5 136.2 78.3 20.8 65.8 51.1 58.5 85.5 56.5 83.9 133.9 137.7 83.3 84.4 90.3 55.9 138.1 133.4 140.3 63.6 29.0 82.3 64.8 138.6 109.7 24.2 133.8 68.9 49.6 80.4 62.5 51.6 30.9 135.2 113.0 53.2 28.1 134.1 76.0 92.5 71.4 42.0 77.8 112.8 176.0 17.9 13.5 22.6 6.5 24.4 26.1 17.1 19.2 26.8 19.3 25.5 24.6 11.8 5.5 13.1 11.4 11.1 19.7 27.9 8.8 38.2 27.3 24.0 18.1 35.9 30.7 14.7 19.5 31.1 12.3 39.9 23.4 41.8 20.6 11.4 9.5 23.3 77.1 27.0 12.3 23.0 58.4 13.9 11.4 29.8 24.8 25.7 31.8 13.0 11.2 22.0 17.8 16.4 6.1 32.7 12.9 5.3 13.2 19.5 21.4 14.8 21.5 22.0 46.8 20.9 13.7 14.2 15.4 14.9 40.0 7.2 18.6 14.5 5.0 17.3 17.4 15.7 15.8 4.8 11.7 15.6 12.9 16.9 9.5 6.0 11.1 17.2 10.4 132.9 137.1 140.9 201.6 133.9 137.7 138.1 133.4 138.6 135.2 134.1 176.0 122.1 44.8 85.4 112.0 164.2 168.8 263.0 73.6 114.4 59.0 112.9 97.0 96.6 41.5 87.1 27.6 100.1 46.7 213.5 110.9 19.6 31.4 2.3 111.2 108.8 113.6 134.3 87.5 51.7 26.9 56.6 142.5 81.1 173.6 136.9 77.9 82.1 43.3 58.5 52.2 53.6 124.2 50.8 100.5 285.8 9.4 92.9 192.3 154.7 62.8 56.2 54.6 76.2 58.3 169.0 32.0 117.7 75.6 169.0 133.3 88.2 14.9 70.1 99.6 111.7 97.8 128.4 33.1 27.7 117.0 151.7 90.3 261.2 43.0 88.6 184.2 CNBD1 FLJ35802 ENSG00000176571 "Cyclic nucleotide binding domain containing 1" Q8NA66 8 86866415-87615219 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 6.6" "Group enriched" "Detected in some" 33 "Early spermatids: 155.4;Late spermatids: 92.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Karpas-707: 4.4;U-266/70: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025037, HPA027469, HPA027786" Uncertain "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA025037: AB_10794318, HPA027469: AB_10599492, HPA027786: AB_10600231" "unprognostic (1.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 155.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 92.3 1.2 0.0 0.0 1.0 0.0 0.0 0.0 2.0 2.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CNDP2 "CN2, CPGL, FLJ10830, HsT2298, PEPA" ENSG00000133313 "Carnosine dipeptidase 2" Q96KP4 18 74495816-74523454 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 334.7;Proximal enterocytes: 629.1;Proximal tubular cells: 487.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 458.7;RPMI-8226: 616.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026196, HPA036898, HPA036899" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 2600000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "CAB026196: , HPA036898: AB_2675370, HPA036899: AB_2675371" "unprognostic (2.81e-2)" "unprognostic (9.96e-2)" "unprognostic (3.28e-1)" "unprognostic (1.19e-3)" "unprognostic (2.57e-2)" "unprognostic (5.06e-2)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.49e-1)" "unprognostic (9.31e-2)" "unprognostic (1.56e-3)" "unprognostic (1.15e-1)" "prognostic favorable (3.50e-6)" "unprognostic (2.37e-3)" "unprognostic (4.65e-3)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" 54.8 40.7 125.3 75.0 147.0 25.1 60.4 139.4 156.9 136.8 113.0 83.6 190.1 44.2 122.8 78.4 140.8 94.4 63.7 123.7 133.2 327.3 261.1 82.3 86.3 143.1 137.4 34.4 100.7 58.5 48.0 75.4 144.7 122.5 79.5 42.1 57.4 101.7 26.6 47.0 255.0 37.9 140.4 137.0 103.5 20.9 143.9 52.5 159.1 22.4 82.2 94.5 47.4 157.6 64.6 85.0 60.5 57.4 72.2 42.5 252.3 66.0 61.7 88.3 87.4 49.6 67.1 80.3 81.4 72.1 69.0 95.0 92.7 124.9 62.7 121.3 36.7 80.2 42.1 79.6 104.6 158.7 119.3 64.5 93.9 76.4 136.6 50.1 78.3 94.6 86.3 458.7 59.1 71.6 84.9 75.6 91.0 42.4 50.3 91.3 69.4 616.6 346.1 264.1 65.3 34.2 51.6 360.2 91.6 143.0 151.5 64.0 82.5 93.9 79.5 21.2 45.2 85.5 380.6 108.1 63.6 113.8 80.2 37.1 115.4 49.0 77.6 166.3 84.4 102.4 61.6 72.2 185.1 110.5 65.5 72.4 15.9 124.6 174.1 161.3 94.5 135.7 125.3 147.0 139.4 156.9 123.7 133.2 143.1 137.4 144.7 140.4 143.9 157.6 39.2 73.7 62.7 16.6 55.7 9.2 40.3 48.6 12.5 33.6 76.5 36.4 26.9 77.2 56.8 119.5 16.7 157.9 47.8 99.0 187.9 168.1 3.3 187.7 49.7 49.6 65.3 23.3 8.8 154.7 130.9 23.5 63.7 334.7 12.0 34.0 40.0 119.8 216.3 43.7 10.8 82.9 75.3 122.9 24.9 4.1 18.6 79.0 17.8 13.1 90.8 86.6 55.6 15.6 51.7 108.9 103.5 16.6 44.4 65.2 629.1 487.6 73.3 31.6 13.1 15.2 22.3 8.3 7.2 27.1 9.7 109.0 38.2 32.8 99.8 53.8 COBLL1 KIAA0977 ENSG00000082438 "Cordon-bleu WH2 repeat protein like 1" Q53SF7 2 164653624-164843679 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 107.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 218.8;Cone photoreceptor cells: 250.2;Microglial cells: 351.3;Syncytiotrophoblasts: 331.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "memory B-cell: 15.0;naive B-cell: 9.4;plasmacytoid DC: 8.1" "Group enriched" "Detected in many" 13 "B-cells: 15.0;dendritic cells: 8.1" "Cell line enhanced" "Detected in many" "Karpas-707: 62.6;RPTEC TERT1: 63.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044933, HPA053344" Enhanced Approved "Cell Junctions" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Cell Junctions" "HPA044933: AB_2679148, HPA053344: AB_2682123" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.38e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-1)" "unprognostic (4.49e-3)" "unprognostic (1.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.76e-2)" "unprognostic (3.65e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.27e-13)" "unprognostic (1.56e-1)" "unprognostic (1.52e-1)" "unprognostic (2.47e-1)" "unprognostic (1.42e-1)" 35.1 51.4 9.5 7.4 8.5 4.1 13.8 6.4 9.2 10.1 28.7 8.0 10.7 4.6 15.6 32.6 4.8 12.3 7.2 6.6 7.1 68.8 107.6 18.2 12.8 8.9 7.9 12.5 43.7 10.9 5.0 50.9 9.4 27.4 7.8 56.8 17.9 28.0 3.3 16.9 7.8 7.4 6.8 9.9 30.0 2.0 12.8 4.8 18.4 7.2 16.2 22.6 16.4 6.3 10.7 2.2 5.9 0.0 7.1 1.3 11.9 34.0 13.3 4.7 5.6 8.9 4.3 1.0 6.9 3.2 5.0 38.4 26.2 21.3 5.6 2.9 10.7 10.5 9.5 36.3 10.2 0.0 0.0 1.8 19.8 1.0 27.6 5.8 21.1 1.3 0.0 62.6 7.5 12.5 0.3 0.1 2.9 25.9 12.8 1.3 22.4 10.4 63.1 36.0 14.4 5.8 16.1 14.7 4.6 11.4 10.7 0.0 9.5 11.3 9.7 3.8 8.3 24.3 10.0 3.6 4.7 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.8 0.0 8.1 0.0 0.4 9.5 8.5 6.4 9.2 6.6 7.1 8.9 7.9 9.4 6.8 12.8 6.3 56.4 70.5 66.5 7.5 102.5 97.3 54.3 14.5 30.7 21.6 22.4 22.4 9.3 30.0 26.0 218.8 250.2 52.1 40.8 11.3 62.6 25.5 0.1 24.6 12.2 47.1 22.2 22.5 23.7 33.8 71.3 35.0 53.5 19.5 34.1 9.0 6.1 127.9 8.7 3.3 30.9 11.0 24.4 3.9 9.0 1.3 14.6 3.7 19.6 351.3 0.7 144.5 0.0 5.0 1.6 29.8 4.9 7.9 154.8 46.0 12.6 28.6 12.4 190.2 46.0 8.6 71.2 0.6 2.7 69.0 70.3 331.4 8.3 8.0 10.0 75.6 COX7B2 ENSG00000170516 "Cytochrome c oxidase subunit 7B2" Q8TF08 4 46734827-46909245 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 70 "testis: 85.8" "Group enriched" "Detected in some" 9 "Early spermatids: 519.2;Late spermatids: 211.0;Spermatocytes: 391.5" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "Karpas-707: 33.9" "Low region specificity" "Detected in many" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 36: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (2.82e-1)" "unprognostic (2.42e-1)" 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 85.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 33.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.9 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 519.2 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 211.0 9.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 391.5 38.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CPEB3 KIAA0940 ENSG00000107864 "Cytoplasmic polyadenylation element binding protein 3" Q8NE35 10 92046692-92291078 "Predicted intracellular proteins" "Translation regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 32.2" "Cell type enhanced" "Detected in many" "Astrocytes: 176.0;Early spermatids: 226.2;Excitatory neurons: 233.7;Inhibitory neurons: 286.9;Late spermatids: 408.9;Oligodendrocyte precursor cells: 148.8;Oligodendrocytes: 128.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 12.1;U-266/70: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070942 Approved "Nucleoplasm,Plasma membrane,Midbody,Cytosol" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Plasma membrane, Midbody" "HPA070942: " "unprognostic (4.90e-2)" "unprognostic (2.12e-2)" "unprognostic (3.00e-1)" "unprognostic (5.66e-2)" "unprognostic (1.92e-1)" "unprognostic (2.95e-5)" "prognostic favorable (5.06e-5)" "unprognostic (4.09e-4)" "unprognostic (2.73e-1)" "unprognostic (2.40e-1)" "unprognostic (1.47e-2)" "unprognostic (2.42e-2)" "prognostic favorable (3.84e-9)" "unprognostic (3.33e-2)" "unprognostic (7.42e-2)" "unprognostic (1.36e-2)" "unprognostic (1.40e-1)" 1.9 3.9 6.1 1.8 7.2 1.7 3.2 6.2 17.3 2.5 2.1 2.3 3.1 1.9 4.5 4.6 1.8 2.0 5.1 6.4 4.3 4.6 32.2 2.2 1.9 10.4 5.6 3.5 3.5 3.2 4.0 1.6 11.0 4.2 2.6 7.1 7.5 2.4 19.7 4.0 3.0 2.0 1.4 2.6 2.8 12.9 4.4 1.5 6.5 9.5 2.1 1.9 3.1 7.0 0.9 0.2 0.3 1.9 0.5 0.5 0.7 0.8 0.6 1.2 0.9 0.6 1.9 1.1 1.0 0.3 0.5 2.5 0.9 0.6 0.7 1.1 0.9 1.4 1.3 0.8 1.4 0.6 1.4 0.4 1.5 0.6 2.4 1.0 1.1 1.3 0.9 12.1 0.5 0.7 0.9 0.8 0.2 1.3 0.9 1.1 1.6 2.1 1.2 0.4 1.4 0.5 0.8 2.2 1.6 1.0 2.7 1.6 0.8 0.6 0.6 0.4 0.7 6.3 1.7 1.1 0.3 2.2 0.1 2.6 0.4 0.8 0.2 0.5 0.2 0.7 0.1 0.3 0.3 0.1 0.1 0.1 0.5 0.2 0.6 0.2 0.1 0.2 6.1 7.2 6.2 17.3 6.4 4.3 10.4 5.6 11.0 1.4 4.4 7.0 6.1 6.4 7.0 176.0 6.2 8.8 4.0 4.0 7.4 26.0 20.5 10.7 25.3 5.7 4.4 12.9 50.1 2.1 3.0 11.3 5.9 3.2 226.2 9.0 3.0 7.1 19.8 3.6 233.7 2.6 1.6 5.5 4.1 10.8 3.8 4.1 12.5 75.2 4.8 30.3 286.9 9.9 8.2 23.9 3.4 408.9 5.9 10.3 5.4 87.1 8.9 3.2 4.1 148.8 128.6 3.2 4.0 7.9 4.2 10.7 10.1 5.0 8.7 24.7 0.0 4.4 4.1 13.2 7.2 22.0 13.9 1.2 3.3 3.4 5.9 6.5 CT45A10 ENSG00000269586 "Cancer/testis antigen family 45 member A10" P0DMU9 X 135881063-135889086 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 9.2" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 47.9" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 85.4;K-562: 26.9;Karpas-707: 94.7;U-266/84: 88.6" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA044735: AB_2679065, HPA044757: AB_2679075, HPA046872: AB_2679849, HPA046987: AB_2679893" "unprognostic (3.55e-1)" "unprognostic (7.08e-3)" "unprognostic (2.08e-1)" 0.0 0.0 0.6 0.1 0.6 0.0 0.0 0.4 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.0 0.0 0.1 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 9.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 85.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 94.7 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.4 0.0 0.0 18.5 88.6 0.1 10.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.4 1.2 1.3 0.4 1.5 0.6 2.0 0.6 1.3 0.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 47.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CTSO CTSO1 ENSG00000256043 "Cathepsin O" P43234 4 155921580-155953912 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 37.1;HSkMC: 44.6;Karpas-707: 85.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002041 Approved "Intracellular and membrane" NA NA 25000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA002041: AB_1078408" "unprognostic (3.96e-3)" "unprognostic (1.62e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (9.10e-3)" "unprognostic (2.55e-1)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (6.62e-2)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.55e-2)" "unprognostic (4.87e-3)" "unprognostic (4.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" 19.1 31.5 8.0 17.8 8.0 5.0 31.9 6.2 11.8 36.7 7.9 19.6 32.8 37.2 36.1 16.7 36.9 40.7 20.2 7.8 7.6 34.5 98.8 36.8 24.5 7.1 7.5 28.0 19.9 24.5 9.6 41.2 6.9 29.8 23.2 5.2 22.1 32.2 6.7 10.0 34.0 30.7 7.0 39.7 15.5 9.4 7.4 14.1 34.5 17.8 17.9 28.0 15.4 7.6 0.8 0.6 4.1 3.7 17.3 37.1 0.2 1.6 18.3 3.3 5.7 0.4 14.4 0.2 1.2 6.8 1.2 0.1 0.2 0.1 2.6 1.6 0.1 0.4 0.5 0.2 18.1 1.4 0.2 44.6 3.5 2.2 1.8 25.6 3.5 0.7 0.3 85.8 11.7 0.7 1.1 0.4 0.7 0.6 0.7 4.8 0.5 1.0 16.8 7.5 0.5 4.3 2.4 9.3 2.3 2.0 4.2 2.6 3.0 13.3 0.7 0.4 2.3 8.3 0.2 0.2 24.4 0.3 18.6 5.3 0.9 0.6 1.2 0.7 3.0 1.2 1.4 0.8 0.4 1.5 1.6 2.0 0.7 3.0 0.9 1.0 3.3 1.4 8.0 8.0 6.2 11.8 7.8 7.6 7.1 7.5 6.9 7.0 7.4 7.6 29.3 38.5 20.8 15.0 19.9 10.5 13.1 11.3 12.0 10.4 20.1 13.0 5.0 44.3 14.3 25.8 2.1 20.5 19.6 15.6 13.7 24.6 0.4 20.9 34.6 28.2 6.7 8.6 1.7 20.7 7.7 51.5 8.6 27.3 8.8 25.0 43.2 58.1 16.3 5.0 1.7 7.9 8.2 29.2 23.7 1.5 30.4 21.4 30.2 7.5 26.5 17.0 22.6 36.7 5.4 12.7 6.3 25.2 7.0 17.5 21.1 10.7 14.5 1.9 19.7 34.0 24.6 0.3 2.1 5.9 9.1 10.5 14.5 14.3 6.6 9.5 CYP20A1 CYP-M ENSG00000119004 "Cytochrome P450 family 20 subfamily A member 1" Q6UW02 2 203238977-203306026 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055872, HPA058461" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions,Actin filaments" No No "Cluster 24: B-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions, Actin filaments" Nucleoplasm "HPA055872: AB_2682951, HPA058461: AB_2683725" "unprognostic (4.72e-2)" "unprognostic (2.06e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.06e-2)" "unprognostic (5.21e-2)" "unprognostic (2.58e-2)" "unprognostic (4.21e-2)" "unprognostic (2.62e-2)" "unprognostic (4.53e-2)" "unprognostic (4.42e-2)" "unprognostic (7.64e-3)" "unprognostic (9.39e-2)" "unprognostic (2.18e-1)" "unprognostic (1.23e-2)" "unprognostic (1.95e-3)" 3.1 3.2 3.1 2.1 4.3 2.2 2.4 4.1 3.4 2.7 4.2 3.6 2.1 2.3 2.4 2.4 1.9 3.2 1.7 2.7 3.0 6.1 4.6 3.5 3.9 4.5 3.8 3.8 3.1 2.9 0.9 3.4 3.8 3.5 3.2 1.7 2.3 2.1 2.6 3.8 2.6 3.2 2.9 3.7 3.7 2.9 4.2 2.2 8.0 1.3 2.9 3.2 1.0 5.7 2.8 4.7 2.9 2.9 12.1 2.9 2.5 5.0 3.3 2.4 1.7 9.1 5.2 1.9 3.8 4.8 4.4 4.0 1.9 2.7 4.6 2.9 1.0 6.1 3.0 3.5 7.2 6.4 3.3 5.5 2.2 5.7 4.9 2.1 6.4 2.8 8.0 9.9 5.1 4.2 4.3 3.7 7.7 2.3 4.2 3.5 3.7 4.5 3.2 9.2 2.0 2.2 0.4 4.0 5.5 3.3 2.7 4.8 8.5 8.4 2.5 4.0 4.1 5.2 4.4 2.3 6.4 2.8 3.6 5.7 5.2 2.1 6.5 5.6 7.1 6.1 8.0 5.9 2.3 9.6 5.9 3.5 3.0 4.9 6.5 7.4 8.0 4.3 3.1 4.3 4.1 3.4 2.7 3.0 4.5 3.8 3.8 2.9 4.2 5.7 41.2 16.0 33.2 24.2 55.5 12.4 41.6 20.2 29.6 42.0 17.1 17.8 33.6 50.1 33.8 16.5 58.4 33.4 55.8 40.3 11.7 18.3 96.6 24.2 33.6 40.5 45.4 45.5 12.1 20.3 23.0 49.0 53.0 23.7 29.1 65.4 88.2 50.4 37.9 50.5 20.5 33.0 22.4 38.1 22.5 21.9 123.0 35.8 7.2 34.7 44.5 32.4 74.2 24.1 39.1 15.2 30.6 83.8 51.7 33.6 30.8 26.2 23.5 70.5 65.7 76.6 45.7 104.5 64.1 25.4 13.4 40.8 54.4 59.7 32.8 28.7 CYP2R1 ENSG00000186104 "Cytochrome P450 family 2 subfamily R member 1" Q6VVX0 11 14877440-14892231 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 176.3;Late spermatids: 106.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 26.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042949 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA042949: AB_2678237" "unprognostic (1.62e-2)" "unprognostic (1.82e-2)" "unprognostic (5.90e-2)" "unprognostic (1.63e-3)" "unprognostic (2.67e-1)" "unprognostic (2.19e-1)" "unprognostic (3.23e-2)" "unprognostic (7.73e-2)" "unprognostic (1.70e-1)" "unprognostic (3.90e-2)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.01e-1)" "unprognostic (1.81e-1)" "unprognostic (1.46e-1)" "unprognostic (1.44e-2)" 2.5 1.8 1.6 3.1 1.9 3.0 4.1 4.9 2.4 2.6 0.5 3.7 4.6 2.2 3.2 4.6 1.8 1.6 2.2 1.6 2.1 1.8 2.2 2.5 3.0 1.7 1.5 2.0 5.2 1.5 2.6 1.0 1.8 2.8 3.3 3.3 4.5 1.4 2.8 6.9 4.4 1.5 1.5 3.0 5.0 4.3 1.6 2.4 1.9 1.6 2.9 3.0 3.3 2.3 6.1 3.7 3.6 1.5 1.5 2.5 0.0 2.1 1.1 1.2 1.3 4.3 6.8 7.6 1.6 0.4 4.7 0.0 1.2 2.8 0.5 6.3 5.8 3.4 4.7 0.3 5.4 5.9 3.4 2.4 10.6 0.0 4.4 1.1 1.4 9.3 5.1 26.0 0.8 1.6 6.5 11.9 3.4 4.4 3.5 4.6 2.6 11.6 1.4 0.7 3.0 4.7 4.5 5.4 5.2 2.3 4.0 2.2 3.8 3.6 4.4 2.2 2.7 12.8 16.1 9.0 5.0 7.6 3.3 2.4 2.0 1.6 3.0 1.9 4.7 1.6 2.5 1.9 1.7 2.8 3.5 3.0 0.3 2.1 2.3 2.0 3.6 1.2 1.6 1.9 4.9 2.4 1.6 2.1 1.7 1.5 1.8 1.5 1.6 2.3 4.4 12.8 4.8 8.5 15.4 5.9 13.9 9.3 12.5 1.9 7.0 5.8 4.3 8.6 7.4 5.5 6.2 0.3 9.8 10.1 5.9 8.1 176.3 1.9 3.3 6.7 6.7 4.6 13.1 16.9 0.2 4.4 14.8 3.9 3.8 7.8 5.0 6.0 5.9 1.7 18.4 5.5 0.0 7.6 12.6 106.7 2.1 7.7 14.2 13.1 6.1 5.0 13.4 14.6 13.3 11.3 2.9 4.1 11.9 6.4 12.6 6.2 2.8 5.0 13.1 3.2 4.9 23.8 20.2 20.4 6.7 0.0 16.4 6.7 8.8 6.1 DBF4 "ASK, chif, DBF4A, ZDBF1" ENSG00000006634 "DBF4 zinc finger" Q9UBU7 7 87876216-87909553 "Predicted intracellular proteins" "Cell cycle, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 15.1" "Group enriched" "Detected in all" 4 "Early spermatids: 468.6;Spermatocytes: 569.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042923 Supported "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 10: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA042923: AB_2678222" "unprognostic (2.48e-1)" "unprognostic (8.32e-2)" "unprognostic (1.15e-2)" "unprognostic (4.86e-3)" "unprognostic (2.81e-2)" "unprognostic (3.63e-1)" "prognostic unfavorable (4.45e-6)" "unprognostic (1.05e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (1.46e-3)" "unprognostic (1.05e-3)" "unprognostic (2.78e-3)" "prognostic unfavorable (6.42e-7)" "unprognostic (1.98e-2)" "unprognostic (2.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" 0.1 0.2 0.2 0.2 0.4 0.6 0.2 0.7 0.4 0.2 0.1 0.2 0.2 0.2 0.3 0.1 0.1 0.4 0.1 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.1 0.2 0.3 0.0 0.1 0.3 0.2 15.1 0.2 0.6 0.3 0.0 0.5 0.1 0.1 0.3 0.9 0.8 2.0 2.5 0.4 0.4 0.5 1.0 0.2 1.0 2.1 1.4 0.6 2.1 0.6 0.6 1.7 0.9 2.2 0.5 1.0 1.6 1.3 1.3 1.0 0.4 0.1 1.7 1.0 0.4 0.6 1.2 1.0 0.3 0.9 1.9 1.2 4.2 1.4 1.7 2.8 2.0 2.0 2.1 1.9 0.7 3.1 2.5 0.8 0.1 3.0 1.8 1.2 2.2 1.0 1.6 0.9 1.6 0.1 1.2 1.4 3.1 2.0 2.3 5.2 2.1 0.8 3.1 2.5 1.0 0.1 0.1 0.3 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.2 0.3 0.2 0.2 0.0 0.2 0.4 0.1 0.2 0.4 0.7 0.4 0.2 0.1 0.2 0.2 0.2 0.1 0.2 0.3 13.3 3.2 12.6 5.5 38.4 15.6 16.4 10.7 12.0 6.6 13.0 16.8 3.7 2.8 7.7 9.2 12.5 19.6 59.2 9.7 3.9 8.3 468.6 12.1 23.6 11.1 14.9 40.8 14.7 14.7 36.4 12.4 14.3 17.7 31.0 19.4 6.4 6.5 16.1 3.3 9.1 20.6 16.2 9.1 15.5 116.0 15.5 20.8 12.4 2.8 11.0 2.1 24.7 6.0 6.7 14.1 8.5 9.4 48.9 18.4 4.2 5.8 10.2 16.6 13.1 9.7 11.4 569.4 74.6 20.5 12.6 9.6 44.4 13.5 22.3 11.7 DCAF8L1 WDR42B ENSG00000226372 "DDB1 and CUL4 associated factor 8 like 1" A6NGE4 X 27977992-27981449 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 3.0" "Group enriched" "Detected in some" 23 "Spermatocytes: 8.0;Spermatogonia: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "Karpas-707: 18.7" HPA043787 Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA043787: AB_10961430" "unprognostic (1.40e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DCD "AIDD, DCD-1, DSEP, HCAP, PIF" ENSG00000161634 Dermcidin P81605 12 54644589-54648493 "Plasma proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 2476.8" "Cell type enriched" "Detected in some" 355 "Melanocytes: 8167.8" "Cancer enriched" "Detected in some" 9 "breast cancer: 91.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "Karpas-707: 1.0" HPA063967 Enhanced "Secreted in other tissues" NA NA 410000000 "Cluster 42: Non-specific - Transcription" "Cluster 61: Skin - Cornification" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA063967: AB_2685163" "unprognostic (3.55e-2)" "unprognostic (1.61e-1)" 100.2 0.4 3.5 0.3 3.3 1.1 354.3 3.4 5.4 0.3 3.8 0.7 0.2 0.7 0.9 0.5 0.2 0.8 1.3 3.5 3.3 0.2 0.9 0.6 0.2 3.3 3.6 0.4 1.0 0.0 0.5 0.1 3.5 0.4 0.2 0.5 0.5 0.1 14.0 2476.8 0.7 0.1 3.0 0.4 0.7 1.1 3.2 0.3 0.5 0.0 0.2 0.2 0.7 4.1 0.2 0.3 0.4 0.4 0.3 0.4 0.4 0.5 0.1 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.4 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.5 0.2 0.0 0.2 0.1 0.3 0.2 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.1 1.9 0.4 0.5 0.4 0.3 0.6 0.5 0.4 0.3 0.2 0.4 0.5 0.5 1.1 0.9 0.7 0.5 0.6 0.2 3.5 3.3 3.4 5.4 3.5 3.3 3.3 3.6 3.5 3.0 3.2 4.1 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.1 0.0 0.0 8167.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.4 0.2 0.0 23.0 0.0 1.0 0.0 0.0 0.0 DCDC2C ENSG00000214866 "Doublecortin domain containing 2C" A8MYV0 2 3703575-3848008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.1" "Group enriched" "Detected in some" 7 "Early spermatids: 171.3;Late spermatids: 59.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA045848 Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA045848: AB_10961120" "unprognostic (2.63e-2)" "unprognostic (1.81e-1)" "unprognostic (3.81e-3)" "unprognostic (6.98e-2)" 0.1 0.0 0.6 0.0 0.5 0.4 0.1 0.9 0.9 0.0 1.2 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.5 0.5 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.4 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.2 4.1 0.6 0.2 0.1 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.9 0.9 0.5 0.5 0.1 0.1 0.2 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 171.3 0.0 0.4 2.3 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 59.9 5.6 0.1 0.0 15.9 0.0 0.0 0.0 0.0 0.2 0.3 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 DCST2 FLJ32934 ENSG00000163354 "DC-STAMP domain containing 2" Q5T1A1 1 155018520-155033781 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 8.5;skin 1: 4.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 16.7;Early spermatids: 53.7;Extravillous trophoblasts: 13.0;Late spermatids: 31.5;Rod photoreceptor cells: 16.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.1;Karpas-707: 1.1;U-266/70: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (8.08e-2)" "unprognostic (5.67e-2)" "unprognostic (6.04e-4)" "unprognostic (1.63e-2)" "unprognostic (3.34e-2)" "unprognostic (1.88e-3)" "unprognostic (8.25e-2)" "unprognostic (2.65e-2)" "unprognostic (2.94e-1)" "unprognostic (1.76e-1)" "unprognostic (1.94e-1)" "unprognostic (8.92e-2)" "unprognostic (2.78e-10)" "unprognostic (6.95e-3)" "unprognostic (9.05e-2)" "unprognostic (1.40e-1)" "unprognostic (5.60e-3)" 0.6 0.3 0.1 0.1 0.2 0.2 1.2 0.2 0.4 1.5 0.1 0.6 1.3 0.5 0.6 0.8 0.8 0.1 0.3 0.1 0.2 0.4 0.6 0.3 0.3 0.2 0.2 0.5 0.3 0.0 0.2 0.2 0.3 1.3 0.4 8.5 1.4 0.6 0.2 4.6 0.9 0.2 0.2 0.2 0.5 3.7 0.2 0.3 0.5 0.0 0.2 0.3 1.5 0.3 0.1 0.1 0.5 0.5 0.2 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.9 0.0 0.1 0.3 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.3 0.2 0.2 0.4 0.6 0.0 0.0 0.0 0.3 0.0 0.0 1.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.4 0.1 0.2 0.2 0.2 0.3 0.2 0.2 0.3 1.0 0.0 0.0 2.6 0.1 0.9 0.8 0.9 0.0 1.2 1.2 1.9 0.3 1.5 0.4 0.0 16.7 0.5 0.0 0.9 0.0 0.1 53.7 2.1 0.2 0.6 0.0 0.0 0.5 0.2 13.0 0.5 0.0 1.1 0.0 0.2 0.4 0.1 0.5 1.7 0.5 1.4 0.0 0.3 0.3 31.5 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.5 0.5 0.2 0.4 0.7 0.1 0.4 1.9 0.4 3.1 16.6 0.0 0.0 0.5 2.2 1.9 0.6 1.3 0.8 0.1 0.1 0.9 0.5 DCTD ENSG00000129187 "DCMP deaminase" P32321 4 182890060-182917936 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035894 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cytosol" "HPA035894: AB_10673488" "unprognostic (1.26e-1)" "unprognostic (9.80e-3)" "unprognostic (3.15e-2)" "unprognostic (3.78e-3)" "unprognostic (3.13e-3)" "unprognostic (2.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.59e-3)" "unprognostic (2.62e-2)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (1.20e-1)" "prognostic favorable (1.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.59e-1)" "unprognostic (3.89e-2)" "unprognostic (1.12e-1)" 50.8 83.8 39.0 41.6 40.3 29.5 46.7 40.1 44.8 48.9 51.1 41.4 33.1 47.8 29.7 61.2 49.0 54.7 40.6 39.8 43.6 48.9 79.8 41.2 45.2 43.0 42.8 65.8 54.9 61.8 46.9 36.7 40.2 39.9 40.9 25.1 44.6 41.7 41.7 39.3 36.3 46.4 43.8 50.3 54.1 21.8 42.6 42.2 100.8 32.9 49.6 50.1 45.6 46.0 97.8 87.4 88.4 81.3 129.6 176.7 115.0 184.1 163.0 128.7 79.7 89.2 183.0 33.5 44.3 179.9 87.1 47.3 65.5 114.9 117.1 163.8 50.4 155.9 50.4 109.1 139.5 153.3 93.3 149.8 120.8 113.6 117.8 129.6 112.2 73.1 157.4 324.5 175.6 71.5 100.1 94.7 70.0 39.8 79.3 107.3 62.2 65.8 107.9 115.1 86.7 54.3 86.7 73.8 87.4 81.2 56.7 78.8 131.7 105.7 81.7 52.0 142.0 124.5 72.9 42.8 117.4 98.5 127.1 68.6 47.9 45.2 61.0 58.8 76.8 71.0 52.6 62.7 55.0 48.6 51.6 54.6 3.3 73.7 60.2 42.4 50.6 55.6 39.0 40.3 40.1 44.8 39.8 43.6 43.0 42.8 40.2 43.8 42.6 46.0 31.6 12.8 19.5 8.8 31.7 25.4 34.4 35.4 37.5 4.9 39.4 34.2 24.3 38.6 21.5 33.1 4.2 19.0 26.6 16.8 37.2 68.8 7.0 19.7 41.6 30.9 14.5 27.1 10.7 54.5 26.8 42.3 15.8 22.3 22.8 36.2 30.0 45.2 53.8 3.3 11.7 28.5 18.3 38.8 32.1 18.0 44.1 29.4 26.6 9.4 34.8 37.4 25.7 3.0 3.1 75.5 18.5 35.3 27.6 46.1 19.3 45.8 18.7 5.5 32.9 25.8 34.6 10.2 15.4 54.5 23.0 7.3 27.6 42.4 31.3 42.3 DENND1B "C1orf218, FAM31B, FLJ20054, MGC27044" ENSG00000213047 "DENN domain containing 1B" Q6P3S1 1 197504748-197775696 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 101.3;Inhibitory neurons: 138.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042586 Uncertain Supported "Nuclear speckles,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nuclear speckles" "HPA042586: AB_2678064" "unprognostic (8.79e-2)" "unprognostic (1.58e-1)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.39e-1)" "unprognostic (7.13e-3)" "unprognostic (2.69e-1)" "unprognostic (9.54e-2)" "unprognostic (7.79e-3)" "unprognostic (3.99e-2)" "unprognostic (3.13e-2)" "unprognostic (5.36e-2)" "unprognostic (6.11e-2)" "unprognostic (5.61e-3)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.35e-2)" 2.0 2.7 2.4 3.8 8.3 5.6 5.7 3.9 3.0 3.1 1.5 6.0 5.7 2.1 4.0 4.4 2.0 3.4 5.8 2.1 4.4 5.6 5.0 4.3 6.5 2.9 5.3 4.0 5.8 5.9 2.5 1.5 3.6 3.8 5.7 5.9 4.5 3.2 3.9 1.9 6.9 1.9 1.9 4.3 4.8 2.2 4.5 6.6 6.0 5.9 6.5 4.0 2.8 2.6 7.2 1.8 2.0 3.4 0.9 5.0 3.0 5.4 3.7 3.3 2.0 1.9 4.5 13.0 2.7 8.3 1.9 3.6 3.2 3.9 2.9 10.0 3.4 4.7 3.7 0.9 2.7 15.5 5.6 1.7 5.2 1.3 3.6 10.0 1.4 7.4 3.6 19.6 3.3 1.3 8.3 7.9 0.7 1.8 1.7 5.1 1.7 10.3 7.9 6.6 3.4 5.3 8.3 5.5 1.5 3.1 2.3 13.4 4.0 0.4 3.1 0.2 3.2 9.8 0.0 6.4 3.4 6.2 6.2 2.3 0.1 1.1 0.9 0.3 0.4 1.2 0.6 1.4 0.7 0.3 0.3 0.6 0.4 2.7 0.3 0.9 1.8 0.3 2.4 8.3 3.9 3.0 2.1 4.4 2.9 5.3 3.6 1.9 4.5 2.6 9.1 41.7 16.2 46.4 24.1 8.4 23.6 9.2 12.0 18.3 28.9 11.9 28.3 15.7 17.3 14.7 25.0 10.4 22.1 65.5 17.6 9.7 26.8 7.9 5.7 6.5 14.4 8.0 101.3 23.1 9.7 10.9 20.9 17.1 64.7 12.8 9.3 15.3 18.9 5.0 138.5 27.4 4.1 18.9 82.4 26.8 23.9 30.0 16.0 42.2 15.8 8.6 28.8 75.4 5.8 22.5 54.5 13.2 50.7 21.9 59.9 16.4 9.6 14.0 0.0 13.9 6.3 8.1 13.9 22.9 12.1 7.4 42.5 5.7 27.9 53.5 DGKE "DAGK6, DGK" ENSG00000153933 "Diacylglycerol kinase epsilon" P52429 17 56834107-56869567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 34.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 181.1;Cone photoreceptor cells: 189.7;Inhibitory neurons: 90.0;Rod photoreceptor cells: 165.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 84.8;MOLT-4: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017167 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "HPA017167: AB_1847638" "unprognostic (1.19e-2)" "unprognostic (2.11e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.92e-5)" "unprognostic (4.20e-2)" "unprognostic (4.87e-2)" "unprognostic (3.37e-1)" "unprognostic (4.27e-2)" "unprognostic (1.19e-3)" "unprognostic (4.75e-2)" "unprognostic (6.07e-3)" "unprognostic (2.68e-1)" "unprognostic (2.55e-2)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-1)" "unprognostic (3.69e-3)" 4.1 2.2 5.4 4.5 6.9 3.1 3.0 9.4 7.4 4.9 7.7 4.9 2.6 6.5 4.2 2.6 4.8 4.6 2.9 5.8 8.1 2.6 2.8 5.2 5.0 3.3 4.7 3.5 3.9 4.1 6.2 2.7 3.4 4.1 3.3 34.5 2.5 3.3 1.2 1.9 4.4 4.3 2.7 6.9 3.7 6.5 6.9 9.8 4.0 2.2 4.3 3.8 4.2 5.8 3.5 3.3 3.0 0.3 0.6 1.0 1.4 5.8 4.7 3.9 4.5 7.7 4.2 5.1 7.0 3.1 1.9 4.2 7.2 3.2 7.8 16.5 9.5 6.6 8.9 5.1 3.3 12.7 8.9 1.9 4.0 4.1 8.0 3.6 5.4 14.7 5.5 84.8 4.8 5.1 30.3 7.1 2.3 4.6 10.0 9.4 12.4 12.2 3.9 7.6 4.7 3.2 4.7 2.5 0.2 1.9 5.3 6.0 5.0 1.1 5.4 1.7 0.9 11.3 25.3 3.4 3.3 7.3 0.3 0.1 0.2 0.0 1.0 0.1 0.7 0.9 0.6 0.7 0.2 0.3 0.7 0.9 0.3 0.7 0.2 0.8 1.7 0.3 5.4 6.9 9.4 7.4 5.8 8.1 3.3 4.7 3.4 2.7 6.9 5.8 51.2 3.2 6.0 10.4 11.3 8.9 13.5 3.1 21.6 181.1 5.0 6.3 6.3 10.0 4.0 16.5 189.7 6.6 16.3 5.6 0.0 7.4 18.3 9.0 9.9 30.6 11.3 2.1 66.0 4.7 3.0 6.9 9.7 19.3 0.0 13.1 29.3 4.0 2.2 8.4 90.0 7.7 8.2 5.0 9.3 9.2 4.4 7.4 3.6 32.8 6.3 18.6 14.4 32.6 14.4 6.0 6.4 5.3 15.1 21.3 1.9 0.1 2.8 165.4 6.6 11.8 10.7 28.5 20.7 9.7 6.7 3.4 18.9 5.7 5.8 13.4 DGLUCY "C14orf159, FLJ39975" ENSG00000133943 "D-glutamate cyclase" Q7Z3D6 14 91060333-91225632 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 163.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;Collecting duct cells: 29.5;Cytotrophoblasts: 30.9;Endometrial ciliated cells: 29.4;Granulosa cells: 49.8;Hofbauer cells: 31.7;Theca cells: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 200.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041423, HPA052932" Approved Supported Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA041423: AB_10795540, HPA052932: AB_2681991" "unprognostic (5.02e-2)" "unprognostic (1.01e-2)" "unprognostic (1.56e-1)" "prognostic favorable (4.28e-4)" "unprognostic (1.28e-1)" "unprognostic (2.26e-1)" "unprognostic (3.58e-2)" "prognostic favorable (9.48e-5)" "unprognostic (3.56e-1)" "prognostic favorable (7.28e-4)" "unprognostic (2.30e-1)" "unprognostic (1.74e-1)" "prognostic favorable (3.77e-15)" "unprognostic (1.50e-1)" "unprognostic (9.51e-2)" "unprognostic (2.75e-2)" "unprognostic (2.57e-3)" 23.9 32.2 38.5 21.4 46.0 21.7 16.7 53.5 49.2 25.0 76.1 33.5 25.1 26.0 17.2 28.4 38.6 22.6 122.3 36.6 39.8 35.6 24.9 25.0 21.6 45.5 51.3 22.9 16.8 47.9 21.5 16.6 42.1 22.8 30.4 8.3 32.2 34.1 143.0 25.6 23.7 32.0 38.0 33.6 38.1 19.0 45.4 27.3 30.1 163.6 19.9 31.9 20.2 45.2 6.2 16.4 8.0 20.1 32.8 30.6 21.0 6.6 17.7 19.3 19.6 10.9 46.7 41.3 46.0 18.8 24.9 18.0 23.0 24.7 7.9 22.8 9.5 27.7 9.1 13.8 47.8 28.5 38.2 47.5 10.5 10.6 4.0 25.3 34.6 22.8 14.0 54.4 18.4 1.4 22.7 27.0 16.4 0.8 1.4 38.2 15.7 30.9 32.7 25.9 22.4 11.2 10.4 17.8 7.3 8.4 32.0 24.5 24.7 5.7 4.8 17.1 5.9 30.9 23.8 14.0 29.6 36.8 3.8 67.5 48.8 30.8 30.1 69.4 30.3 34.0 19.3 24.5 72.9 22.4 15.9 20.0 200.5 21.0 60.7 22.0 45.2 29.0 38.5 46.0 53.5 49.2 36.6 39.8 45.5 51.3 42.1 38.0 45.4 45.2 19.2 28.9 16.4 0.0 4.3 0.0 0.0 0.0 0.0 0.0 11.5 13.2 0.0 0.0 5.6 29.5 0.0 30.9 12.5 0.0 21.5 17.6 0.0 29.4 14.8 6.2 0.0 0.0 0.0 5.8 15.8 7.4 0.0 25.0 7.6 49.8 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 7.2 0.0 0.0 0.0 0.0 6.3 0.0 0.0 2.7 0.0 0.0 17.0 5.1 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 16.8 8.7 35.6 0.0 0.0 DMAC2L "ATP5S, ATPW, HSU79253" ENSG00000125375 "Distal membrane arm assembly complex 2 like" Q99766 14 50312324-50335558 "Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 60.5;Cytotrophoblasts: 36.6;Extravillous trophoblasts: 24.6;Hofbauer cells: 28.5;Syncytiotrophoblasts: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062690 Approved Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Mitochondria" "HPA062690: AB_2684836" "unprognostic (2.24e-2)" "unprognostic (3.44e-3)" "unprognostic (7.85e-2)" "unprognostic (1.71e-1)" "unprognostic (8.53e-3)" "unprognostic (2.92e-2)" "unprognostic (2.21e-1)" "prognostic favorable (5.53e-4)" "unprognostic (5.73e-2)" "unprognostic (2.98e-1)" "unprognostic (1.02e-3)" "unprognostic (1.91e-1)" "prognostic favorable (2.37e-8)" "unprognostic (5.64e-2)" "unprognostic (1.67e-1)" "unprognostic (1.72e-1)" "unprognostic (2.95e-1)" 8.0 5.6 3.9 5.5 6.2 13.5 8.6 4.1 5.7 6.9 3.0 6.8 10.3 6.3 7.1 10.0 5.2 6.9 10.0 3.4 4.3 8.0 7.5 5.4 8.6 5.4 4.9 4.7 10.8 8.8 3.8 3.7 5.1 6.2 6.3 10.1 6.7 5.0 15.7 10.8 7.3 3.8 4.7 5.9 6.3 15.4 4.2 6.3 12.9 8.9 7.6 7.2 4.2 9.7 18.8 6.7 8.5 5.6 7.2 11.8 18.8 5.9 8.5 11.4 13.3 9.5 10.4 21.1 5.9 8.8 5.4 10.9 2.3 6.3 6.8 10.9 5.0 9.1 5.4 22.5 5.6 20.6 17.6 12.0 11.3 3.5 6.5 3.0 8.9 14.3 5.4 25.9 8.0 14.2 5.2 7.7 6.2 14.0 7.7 10.2 9.6 8.7 9.1 20.4 11.2 9.1 6.9 14.5 13.4 3.1 18.6 10.4 4.2 11.3 15.4 5.3 7.4 13.2 12.4 12.2 3.4 10.2 10.4 20.5 13.1 19.8 14.3 15.6 12.4 19.3 11.7 13.5 9.9 17.1 13.8 15.4 2.5 12.3 20.4 19.0 14.5 12.5 3.9 6.2 4.1 5.7 3.4 4.3 5.4 4.9 5.1 4.7 4.2 9.7 9.4 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.5 0.0 0.0 0.0 0.0 36.6 12.5 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 24.6 6.3 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 41.7 1.9 0.0 0.0 0.0 DNAAF1 "CILD13, DAU1, FLJ25330, LRRC50, ODA7, swt" ENSG00000154099 "Dynein axonemal assembly factor 1" Q8NEP3 16 84145287-84178767 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 22.7;testis: 45.3" "Cell type enhanced" "Detected in many" "Early spermatids: 116.2;Endometrial ciliated cells: 311.3;Plasma cells: 225.4;Respiratory ciliated cells: 494.5;Spermatocytes: 116.2" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 3.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.3" "Group enriched" "Detected in many" 4 "granulocytes: 2.3;T-cells: 1.0" "Cell line enhanced" "Detected in some" "Hep G2: 1.7;Karpas-707: 4.9;PC-3: 1.4;SK-BR-3: 1.4;U-266/70: 4.0;U-266/84: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041166, HPA074239" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "Nuclear speckles" "HPA041166: AB_10794190, HPA074239: AB_2732250" "unprognostic (5.25e-3)" "unprognostic (2.40e-2)" "unprognostic (2.77e-2)" "prognostic favorable (2.14e-4)" "unprognostic (1.42e-1)" "unprognostic (9.99e-2)" "unprognostic (1.25e-1)" "unprognostic (4.48e-2)" "unprognostic (7.71e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-5)" "unprognostic (2.70e-2)" "unprognostic (4.61e-3)" "unprognostic (1.77e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-4)" "unprognostic (7.51e-4)" 0.3 0.7 1.4 0.1 1.2 1.2 0.3 1.1 1.9 2.2 9.7 0.3 0.0 0.5 1.4 0.4 22.7 0.0 0.4 1.6 1.5 1.0 0.8 3.5 0.0 4.1 7.3 0.4 0.3 0.3 2.4 0.2 4.3 0.2 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.0 3.0 0.7 0.2 45.3 1.6 0.0 1.6 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 4.0 2.8 0.4 0.1 0.0 0.0 1.3 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 2.3 0.3 0.1 0.4 1.0 0.3 1.4 1.2 1.1 1.9 1.6 1.5 4.1 7.3 4.3 3.0 1.6 1.3 1.1 0.0 12.4 1.6 5.7 0.6 1.5 9.6 0.0 1.4 4.5 1.5 0.7 1.5 67.2 3.7 54.2 0.2 0.5 0.1 0.0 1.3 116.2 311.3 4.4 1.9 0.0 0.0 9.6 0.4 0.4 2.4 0.5 14.6 3.8 2.6 2.2 0.6 1.9 0.0 5.2 0.0 18.3 7.0 1.5 26.7 1.2 21.6 87.2 0.0 0.8 2.4 1.0 0.5 0.6 0.9 0.0 0.4 225.4 1.4 0.0 1.7 494.5 51.0 0.0 1.6 7.3 116.2 17.0 0.2 0.3 0.4 4.5 1.2 0.3 0.9 DNAJB1 "Hsp40, HSPF1, RSPH16B, Sis1" ENSG00000132002 "DnaJ heat shock protein family (Hsp40) member B1" P25685 19 14514769-14560391 "Cancer-related genes, Predicted intracellular proteins" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1705.1" "Cell type enhanced" "Detected in all" "Langerhans cells: 1392.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 1705.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017450, HPA063247" Enhanced Supported Nucleoplasm NA Yes 23000 "Cluster 20: T-cells - T-cell receptor" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB017450: AB_10631418, HPA063247: AB_2684971" "unprognostic (3.75e-2)" "unprognostic (2.23e-1)" "unprognostic (1.46e-1)" "unprognostic (2.12e-1)" "unprognostic (1.60e-1)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.74e-2)" "unprognostic (3.83e-1)" "unprognostic (1.85e-1)" "unprognostic (7.91e-3)" "unprognostic (2.17e-1)" "prognostic favorable (5.96e-4)" "unprognostic (2.20e-2)" "unprognostic (4.44e-2)" "unprognostic (2.00e-2)" "unprognostic (6.77e-2)" 206.0 216.1 228.5 40.9 241.7 133.8 62.0 320.9 1705.1 188.1 259.4 86.7 35.2 54.0 40.8 439.9 75.3 183.7 182.8 243.8 240.2 245.0 230.3 286.0 42.0 250.4 251.8 231.9 89.8 66.4 148.4 123.4 285.4 73.9 48.4 81.2 109.7 127.1 51.2 128.5 62.7 54.5 240.6 104.5 149.1 149.4 241.8 107.3 97.2 208.0 76.5 133.6 257.7 323.4 192.5 212.5 80.8 81.7 146.8 114.1 45.6 125.9 99.9 210.4 158.8 126.3 106.7 54.8 135.4 121.0 135.5 144.9 169.1 96.7 150.3 55.0 76.1 86.7 115.0 275.6 94.6 57.9 78.5 61.0 237.5 85.3 73.4 114.7 71.6 35.7 131.2 471.6 123.6 130.5 102.2 60.1 80.4 285.9 228.3 73.7 106.3 121.7 101.8 62.4 67.0 51.1 121.1 233.7 127.1 90.8 60.3 60.6 64.7 156.4 98.0 184.1 264.8 193.5 141.7 65.7 114.4 109.2 151.1 68.8 92.4 116.2 171.6 159.0 184.8 93.7 244.5 214.9 76.0 92.0 281.6 219.9 137.6 125.1 172.2 45.1 270.9 322.6 228.5 241.7 320.9 1705.1 243.8 240.2 250.4 251.8 285.4 240.6 241.8 323.4 750.2 157.0 95.4 32.3 248.7 425.8 1142.1 148.0 719.3 60.9 468.8 476.4 367.1 72.9 118.6 23.9 118.9 135.6 214.2 459.6 41.1 132.8 491.8 374.8 339.3 397.3 407.3 60.0 10.2 162.6 199.3 661.2 408.7 552.8 339.4 100.2 86.7 59.9 158.1 52.2 8.9 420.1 81.4 85.1 1392.1 475.3 63.3 559.3 503.4 23.4 31.3 160.7 25.7 3.0 16.5 123.8 380.7 36.9 697.0 461.1 117.3 59.1 138.0 164.7 26.3 398.9 673.3 290.2 53.4 1186.0 478.9 274.9 948.4 104.8 393.7 606.2 DNAJC1 "DNAJL1, ERdj1, MTJ1" ENSG00000136770 "DnaJ heat shock protein family (Hsp40) member C1" Q96KC8 10 21756548-22003769 "Predicted membrane proteins, Transcription factors" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013432 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Endoplasmic reticulum" "HPA013432: AB_1847797" "unprognostic (7.00e-2)" "unprognostic (9.81e-2)" "unprognostic (3.61e-1)" "unprognostic (5.12e-2)" "unprognostic (5.51e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (1.96e-5)" "unprognostic (3.81e-2)" "unprognostic (1.21e-1)" "unprognostic (3.46e-2)" "unprognostic (1.09e-1)" "unprognostic (9.36e-2)" "prognostic favorable (2.33e-4)" "unprognostic (4.44e-3)" "unprognostic (4.88e-2)" "unprognostic (1.45e-2)" "unprognostic (2.22e-2)" 17.6 16.9 9.9 16.3 11.2 18.3 20.0 10.6 13.1 17.8 15.0 20.6 28.3 15.5 13.4 16.3 14.2 17.7 15.8 9.0 12.9 23.0 36.9 24.0 15.6 12.1 11.1 14.0 38.5 45.6 19.6 19.9 12.4 23.7 18.7 7.1 40.7 16.3 12.7 14.3 22.4 15.8 11.5 15.2 28.6 9.4 11.3 13.1 29.0 11.2 13.0 26.5 15.2 12.7 38.5 24.5 53.9 20.1 49.3 34.9 23.4 50.9 22.1 20.8 32.7 33.8 33.1 16.9 21.9 31.2 31.2 36.1 12.3 25.7 11.5 88.6 41.1 40.3 18.8 20.3 119.5 3.0 16.5 35.8 46.5 24.7 28.3 30.4 27.8 16.4 42.7 93.6 23.8 39.2 9.6 12.9 7.1 33.2 20.3 13.8 18.8 62.3 29.1 9.1 11.3 17.1 37.7 62.2 38.1 58.7 19.8 42.8 42.7 20.3 43.5 34.4 29.3 29.8 10.0 11.7 30.3 126.1 12.3 11.8 16.6 7.0 36.2 16.6 36.5 8.4 20.2 29.1 15.3 12.3 12.9 16.5 9.3 34.2 30.9 39.6 15.8 15.0 9.9 11.2 10.6 13.1 9.0 12.9 12.1 11.1 12.4 11.5 11.3 12.7 56.4 35.3 26.9 73.4 46.7 38.7 64.8 26.6 30.1 27.9 67.9 76.1 16.9 57.2 31.0 31.3 45.9 16.7 92.9 52.4 27.4 73.6 47.6 40.9 74.6 54.7 38.3 49.0 134.4 74.2 92.6 67.4 59.7 58.3 41.8 14.3 52.8 84.5 55.0 38.7 77.1 75.8 28.5 43.7 52.5 19.6 94.8 44.2 67.6 112.4 46.9 37.4 99.9 91.5 137.7 80.6 49.2 67.0 202.7 71.2 57.9 80.1 23.9 149.1 59.2 49.3 56.7 232.2 109.5 45.3 44.2 35.3 81.5 41.0 55.8 71.9 DPYSL2 "CRMP2, DHPRP2, DRP-2, DRP2" ENSG00000092964 "Dihydropyrimidinase like 2" Q16555 8 26514031-26658178 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 549.9" "Cell type enhanced" "Detected in all" "Adipocytes: 362.9;Oligodendrocytes: 367.2" "Cancer enhanced" "Detected in all" "glioma: 89.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 65.8;intermediate monocyte: 74.5;myeloid DC: 71.2;non-classical monocyte: 48.8;plasmacytoid DC: 42.2" "Group enriched" "Detected in all" 5 "dendritic cells: 71.2;monocytes: 74.5" "Cell line enhanced" "Detected in many" "ASC diff: 263.7;Karpas-707: 279.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002381, CAB018719" Supported Supported "Plasma membrane,Cytosol" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "CAB018719: AB_2085366, HPA002381: AB_1847244" "unprognostic (2.88e-2)" "unprognostic (1.01e-2)" "unprognostic (9.51e-2)" "unprognostic (3.16e-3)" "unprognostic (8.23e-2)" "unprognostic (1.68e-2)" "unprognostic (1.51e-1)" "unprognostic (9.95e-3)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (1.79e-2)" "unprognostic (4.13e-2)" "unprognostic (5.58e-2)" "unprognostic (9.32e-3)" "unprognostic (1.23e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (5.41e-5)" 60.0 34.8 252.6 22.5 348.0 3.5 48.0 332.4 266.7 25.3 0.0 44.8 10.4 24.9 11.4 18.3 29.6 29.4 58.6 276.1 263.2 21.3 17.6 78.2 17.4 362.4 296.0 40.8 11.0 7.1 22.1 43.7 389.9 19.7 19.0 64.0 18.5 14.9 19.2 25.8 27.6 32.9 257.9 33.6 21.5 11.2 305.0 19.3 22.5 25.8 20.1 35.6 26.9 549.9 22.0 104.1 100.2 53.9 263.7 120.6 9.8 41.9 97.0 39.2 50.6 41.0 31.0 32.7 29.7 131.7 78.8 20.9 106.6 42.0 37.1 74.2 9.2 37.0 36.9 57.9 168.5 8.0 14.5 150.8 59.5 107.1 61.9 125.5 80.0 24.9 1.1 279.1 39.9 13.9 64.3 8.1 78.8 69.9 20.0 84.3 40.3 21.8 66.2 25.0 45.6 95.8 51.0 0.5 28.6 65.7 7.8 14.8 145.0 88.2 34.8 74.3 18.5 39.1 43.3 24.8 127.7 48.1 46.0 1.3 65.8 0.6 9.1 74.5 3.3 8.5 8.1 6.2 71.2 4.4 4.0 5.2 1.7 11.3 48.8 42.2 13.3 30.3 252.6 348.0 332.4 266.7 276.1 263.2 362.4 296.0 389.9 257.9 305.0 549.9 362.9 131.4 71.7 193.9 11.5 40.4 1.0 13.2 2.2 111.4 44.4 58.4 105.0 84.4 19.4 22.0 31.3 15.1 64.8 4.5 3.9 21.4 3.1 41.6 154.3 154.6 60.7 22.3 191.9 2.0 9.1 144.9 6.1 33.6 20.8 33.0 211.3 22.8 51.1 141.3 157.0 87.0 4.1 223.5 192.3 10.6 109.0 111.1 120.9 81.5 163.5 165.2 22.6 102.1 367.2 12.6 6.2 89.5 6.5 1.1 4.7 24.4 10.5 38.6 138.1 51.8 110.6 3.8 17.0 1.6 33.8 4.5 14.8 16.8 12.1 1.2 DYNAP "C18orf26, FLJ39106" ENSG00000178690 "Dynactin associated protein" Q8N1N2 18 54587757-54599493 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "esophagus: 29.3" "Cell type enriched" "Detected in single" 4 "Squamous epithelial cells: 1.7" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 12.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA011148 Uncertain NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA011148: AB_1845609" "unprognostic (9.88e-2)" "unprognostic (2.51e-2)" "unprognostic (1.75e-3)" "unprognostic (1.45e-1)" "unprognostic (8.09e-3)" 0.8 0.4 1.7 0.6 1.3 2.2 0.6 2.2 2.4 0.6 0.0 0.6 0.6 1.0 2.1 29.3 0.5 0.6 1.0 1.4 1.8 0.9 0.8 0.5 1.1 0.9 0.4 0.8 0.4 0.3 0.0 0.4 1.2 0.3 0.7 2.6 1.9 0.5 0.8 1.1 0.5 0.8 0.1 2.4 0.4 1.0 1.5 0.3 0.5 0.4 1.9 0.3 0.2 2.4 0.5 0.2 1.3 0.6 0.6 1.4 1.3 0.3 0.5 1.0 1.0 0.7 0.5 0.7 0.5 0.6 1.1 0.5 0.9 0.0 0.5 0.2 0.2 0.2 0.9 0.4 0.5 0.7 0.6 0.6 0.1 0.9 0.3 0.3 0.2 0.6 1.0 12.9 0.1 0.2 0.5 0.4 2.0 0.2 0.3 0.5 1.5 0.6 0.3 0.7 0.5 0.7 0.2 0.3 2.4 0.9 0.4 0.8 2.2 0.4 2.4 0.5 0.4 0.5 0.4 1.0 0.6 0.3 0.3 0.3 0.3 0.6 0.2 0.3 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.1 0.8 0.2 0.8 0.2 0.0 0.0 1.7 1.3 2.2 2.4 1.4 1.8 0.9 0.4 1.2 0.1 1.5 2.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 EFCAB13 "C17orf57, FLJ40342" ENSG00000178852 "EF-hand calcium binding domain 13" Q8IY85 17 47323290-47441312 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 20.5" "Group enriched" "Detected in many" 4 "Early spermatids: 169.8;Late spermatids: 185.7;Spermatocytes: 64.1" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002501, HPA021633, HPA023249, HPA026561" Uncertain Enhanced "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "Nuclear speckles" "CAB002501: AB_564092, HPA021633: AB_1845594, HPA023249: AB_1845595, HPA026561: AB_1845596" "unprognostic (1.66e-1)" "unprognostic (3.48e-1)" "unprognostic (1.24e-2)" "unprognostic (2.40e-2)" "unprognostic (6.71e-2)" "unprognostic (3.04e-2)" "unprognostic (3.04e-1)" "unprognostic (1.40e-1)" "unprognostic (7.43e-2)" "unprognostic (8.79e-3)" "unprognostic (8.75e-2)" "unprognostic (1.75e-2)" "unprognostic (1.46e-5)" "unprognostic (1.68e-1)" "unprognostic (1.61e-1)" "unprognostic (8.10e-2)" "unprognostic (1.90e-3)" 3.2 2.6 1.3 3.2 2.3 3.9 4.2 3.7 2.0 3.8 0.9 2.9 4.8 6.0 4.0 1.6 3.5 2.9 2.5 1.1 2.9 5.4 3.5 3.1 4.5 2.9 2.5 3.8 1.8 3.2 2.5 3.6 3.3 2.7 3.3 3.9 2.3 1.9 0.8 2.2 3.3 2.4 1.7 4.4 3.6 20.5 2.8 1.8 14.2 0.4 3.2 2.6 2.4 4.3 0.9 3.7 1.5 0.2 1.8 6.4 2.8 2.1 0.4 0.6 1.0 1.7 5.2 0.3 5.8 0.7 0.0 1.0 0.0 0.4 3.5 0.1 0.5 4.9 3.4 0.5 1.8 3.8 0.5 1.2 1.7 2.4 0.0 4.4 4.1 3.8 1.5 9.0 2.2 0.1 1.7 2.1 0.8 2.6 2.9 4.5 1.1 1.8 8.3 3.0 1.1 0.5 1.1 0.1 2.5 1.1 6.0 4.5 1.5 0.2 1.1 0.3 1.0 9.4 6.9 0.9 5.5 7.3 3.8 2.8 1.0 0.3 0.5 0.6 0.4 2.2 0.4 0.3 0.5 2.6 1.2 0.7 0.0 0.5 0.4 0.3 0.1 0.3 1.3 2.3 3.7 2.0 1.1 2.9 2.9 2.5 3.3 1.7 2.8 4.3 5.3 9.6 2.2 7.2 7.9 0.8 1.8 0.9 0.6 2.5 2.3 2.4 6.2 1.5 1.3 0.0 0.0 0.3 1.3 0.4 0.0 1.0 169.8 1.9 2.5 6.0 3.0 1.3 8.0 0.9 0.1 4.1 2.6 5.4 6.3 1.3 4.6 0.5 1.9 3.3 10.1 0.4 2.0 2.9 2.0 185.7 1.8 2.6 0.0 32.8 2.7 1.0 0.0 13.0 19.5 1.1 0.3 3.8 1.4 1.1 1.2 1.6 3.3 2.9 0.0 3.2 4.0 64.1 24.5 0.0 0.6 0.0 2.3 1.2 0.7 1.3 EHD1 "FLJ42622, FLJ44618, H-PAST, HPAST1, PAST1" ENSG00000110047 "EH domain containing 1" Q9H4M9 11 64851642-64888296 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 151.6;testis: 159.9" "Group enriched" "Detected in all" 10 "Early spermatids: 1033.0;Late spermatids: 1950.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA066751, HPA067747" Approved Supported "Plasma membrane" NA NA 10000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713, HPA067747: AB_2685896" "unprognostic (1.51e-1)" "unprognostic (3.21e-1)" "unprognostic (6.35e-3)" "unprognostic (2.43e-1)" "unprognostic (1.62e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.81e-5)" "unprognostic (1.46e-3)" "unprognostic (9.10e-3)" "unprognostic (9.44e-2)" "unprognostic (2.11e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (6.37e-2)" "unprognostic (9.88e-2)" "unprognostic (2.74e-1)" "unprognostic (2.59e-2)" 39.7 25.4 21.5 59.7 26.6 151.6 21.8 38.6 32.6 26.2 18.2 32.3 33.8 28.1 8.4 26.0 27.0 25.0 39.3 24.9 26.8 31.2 22.0 44.7 65.6 32.7 28.2 13.6 11.1 8.9 7.0 35.4 29.9 18.8 14.5 3.0 16.6 20.9 32.1 34.4 38.5 28.3 31.0 74.4 29.3 159.9 30.5 28.9 19.3 31.5 50.3 55.3 23.0 33.4 109.4 74.1 26.2 28.9 31.2 50.2 15.4 108.2 97.4 89.5 51.8 96.5 66.2 142.0 37.8 129.9 76.5 86.6 27.3 108.9 34.5 89.5 15.2 94.8 37.1 49.1 36.8 30.9 24.6 22.8 22.9 138.7 43.2 40.6 89.8 27.6 39.6 243.8 68.7 57.8 62.5 51.4 17.5 27.5 95.9 24.8 83.5 49.9 84.5 35.7 18.6 16.6 60.8 109.3 48.6 29.5 149.2 21.8 127.9 39.6 35.4 106.0 52.6 100.2 48.5 112.1 103.3 40.1 22.0 18.0 13.9 99.6 39.0 16.1 39.2 24.0 27.3 33.8 7.2 18.2 16.2 23.1 57.1 25.4 33.7 8.7 31.8 30.7 21.5 26.6 38.6 32.6 24.9 26.8 32.7 28.2 29.9 31.0 30.5 33.4 31.2 76.9 30.3 4.2 46.0 67.3 52.8 39.4 17.6 3.8 28.8 24.8 29.2 18.6 22.9 14.7 2.1 88.6 76.5 75.9 7.9 29.4 1033.0 41.9 24.4 29.3 6.6 19.8 1.7 40.8 24.5 32.4 25.5 54.9 93.8 37.2 10.4 10.9 32.2 5.0 3.5 27.7 12.2 37.4 61.0 1950.6 30.1 79.6 26.6 1.9 34.3 5.9 78.2 2.5 12.2 101.5 47.7 27.1 50.8 28.2 38.9 41.9 16.5 2.8 78.9 47.9 53.5 55.0 27.4 19.9 49.2 137.0 71.7 19.8 22.1 42.7 EIF4E3 MGC39820 ENSG00000163412 "Eukaryotic translation initiation factor 4E family member 3" Q8N5X7 3 71675414-71754773 "Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 14.7" "Group enriched" "Detected in many" 7 "granulocytes: 14.7;monocytes: 4.2;T-cells: 5.7" "Cell line enhanced" "Detected in many" "HDLM-2: 28.0;Karpas-707: 36.3;U-937: 50.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058649, HPA076465" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoli fibrillar center" "HPA058649: AB_2683785, HPA076465: " "unprognostic (3.16e-3)" "unprognostic (7.60e-3)" "unprognostic (4.28e-2)" "unprognostic (1.67e-2)" "unprognostic (1.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.31e-2)" "prognostic favorable (6.63e-4)" "unprognostic (3.10e-2)" "prognostic favorable (4.64e-5)" "unprognostic (3.16e-2)" "unprognostic (4.58e-2)" "prognostic favorable (6.99e-5)" "unprognostic (3.09e-1)" "unprognostic (1.85e-1)" "unprognostic (3.64e-2)" "unprognostic (1.83e-2)" 27.5 12.0 13.5 12.7 17.5 26.6 13.9 10.7 18.3 11.5 1.7 18.0 14.2 14.5 9.8 19.6 15.7 10.6 29.9 17.5 12.3 13.9 11.7 16.1 12.7 8.7 10.0 22.7 15.9 24.5 9.8 6.3 8.1 16.0 17.0 8.2 14.3 18.2 61.8 9.7 18.6 17.3 10.6 17.7 12.7 5.6 15.7 15.8 17.4 54.5 10.9 15.1 9.9 15.5 0.6 2.5 2.4 7.8 2.3 5.9 3.0 2.1 2.3 2.1 1.2 1.3 1.2 0.0 5.1 2.0 13.4 2.8 8.6 12.1 1.7 28.0 2.7 0.0 0.2 0.2 8.2 4.3 4.6 5.3 7.5 0.6 6.4 1.1 6.7 4.9 0.9 36.3 0.4 9.4 3.9 1.0 18.9 0.9 4.3 2.1 9.4 1.2 25.9 13.3 4.8 12.9 14.4 3.1 0.3 7.4 13.6 0.2 1.8 1.2 5.9 16.6 2.0 25.2 25.0 0.0 0.9 50.3 4.8 2.0 4.2 6.1 2.1 1.8 3.2 0.2 2.9 3.5 0.9 0.1 2.1 2.5 14.7 1.1 2.6 0.0 5.7 1.7 13.5 17.5 10.7 18.3 17.5 12.3 8.7 10.0 8.1 10.6 15.7 15.5 16.6 28.9 14.5 5.5 1.9 10.1 10.3 2.0 5.2 9.4 14.5 10.3 39.3 11.5 7.4 11.0 0.0 3.7 20.3 41.0 3.9 5.2 1.0 8.6 19.0 11.0 9.1 1.7 37.0 5.8 3.0 12.5 7.1 35.2 7.0 6.4 17.5 7.3 3.9 1.7 32.0 10.8 2.0 19.5 6.2 1.7 12.8 15.8 3.6 11.2 31.2 13.0 17.5 11.6 11.9 8.6 17.1 9.4 10.9 12.2 40.0 14.9 8.1 0.5 0.0 11.5 14.1 0.6 1.3 8.3 13.5 1.5 20.8 2.6 10.1 9.5 ENPP6 MGC33971 ENSG00000164303 "Ectonucleotide pyrophosphatase/phosphodiesterase 6" Q6UWR7 4 184088706-184221230 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.4;kidney: 30.6;ovary: 12.5" "Cell type enhanced" "Detected in some" "Oligodendrocytes: 119.9;Peritubular cells: 35.3;Proximal tubular cells: 31.3;Theca cells: 23.9" "Cancer enriched" "Detected in some" 5 "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 3.2;SH-SY5Y: 3.6;U-266/70: 2.9;U-266/84: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042740, HPA069197" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 290000 "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA042740: AB_10793984, HPA069197: " "unprognostic (4.81e-4)" "unprognostic (1.47e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.56e-1)" "unprognostic (6.69e-3)" "unprognostic (3.07e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "unprognostic (7.60e-3)" "unprognostic (3.04e-2)" "unprognostic (1.72e-1)" "unprognostic (2.98e-2)" "unprognostic (2.82e-1)" "unprognostic (3.93e-3)" "unprognostic (2.01e-1)" 0.2 0.3 2.7 0.8 11.8 0.9 0.8 14.2 5.5 0.2 2.3 1.0 1.7 0.2 6.1 1.0 0.3 0.5 0.2 2.7 6.1 30.6 0.1 0.3 0.9 20.4 9.6 12.5 0.0 0.0 4.2 0.1 18.1 2.2 1.0 0.1 0.7 6.1 0.2 0.1 2.2 0.1 12.5 1.0 1.2 2.4 11.1 1.9 0.1 1.3 2.8 0.6 0.3 29.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 2.7 11.8 14.2 5.5 2.7 6.1 20.4 9.6 18.1 12.5 11.1 29.4 0.5 0.0 0.0 5.9 0.1 0.0 0.2 0.9 0.6 0.0 0.1 0.5 0.9 0.0 0.4 1.8 0.0 0.0 0.0 0.0 3.9 1.1 1.0 0.0 0.0 0.5 0.0 0.0 4.3 0.2 0.0 8.7 0.0 0.0 5.7 0.0 0.0 0.4 0.2 0.0 1.5 0.0 0.0 0.6 0.0 0.4 4.1 0.6 1.8 4.7 1.1 0.0 0.0 6.6 119.9 0.0 0.0 35.3 0.5 0.1 0.0 31.3 0.2 0.0 0.0 5.1 0.6 0.1 1.6 0.0 0.0 0.0 0.3 23.9 0.0 0.3 ENTPD1 "ATPDase, CD39, NTPDase-1, SPG64" ENSG00000138185 "Ectonucleoside triphosphate diphosphohydrolase 1" P49961 10 95711779-95877266 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 74.1;Kupffer cells: 110.4;Langerhans cells: 161.3;Microglial cells: 217.4;monocytes: 112.2;Plasma cells: 80.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 17.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 102.2" "Group enriched" "Detected in all" 4 "dendritic cells: 31.9;granulocytes: 102.2;monocytes: 41.0" "Group enriched" "Detected in many" 7 "HDLM-2: 147.5;Karpas-707: 135.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002494, HPA014067, CAB079986" Enhanced Uncertain Microtubules NA NA 19000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Microtubules "CAB002494: AB_563557, CAB079986: , HPA014067: AB_1848178" "unprognostic (1.14e-1)" "unprognostic (1.01e-2)" "unprognostic (3.11e-1)" "unprognostic (5.67e-2)" "unprognostic (9.68e-3)" "unprognostic (3.45e-3)" "unprognostic (6.31e-2)" "unprognostic (5.26e-3)" "unprognostic (2.73e-1)" "unprognostic (1.28e-2)" "unprognostic (6.40e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (5.33e-5)" "unprognostic (9.79e-2)" "unprognostic (2.30e-1)" "prognostic favorable (7.89e-4)" "unprognostic (5.09e-2)" 11.8 8.3 5.9 24.7 5.5 27.5 10.8 5.0 6.3 17.5 5.0 14.3 9.3 28.0 19.3 19.2 14.0 27.7 8.5 5.3 6.3 7.6 5.4 16.1 20.2 7.1 6.5 5.5 2.8 3.4 3.9 11.4 7.7 11.2 12.8 6.8 6.0 18.1 4.0 6.3 11.7 49.7 6.2 21.5 7.3 4.5 7.5 6.8 20.0 8.7 25.6 30.6 11.0 6.3 1.4 2.7 5.4 7.1 0.1 0.1 5.0 4.5 1.2 0.0 0.0 4.0 1.6 8.2 3.1 0.0 5.3 2.2 0.0 0.0 0.0 147.5 5.2 7.2 4.0 4.3 0.0 12.5 4.1 0.1 0.0 0.6 0.0 2.4 18.2 2.0 5.3 135.4 0.1 4.4 4.7 5.8 5.9 3.6 2.8 15.3 2.4 4.4 1.7 2.2 5.1 6.2 3.6 3.7 3.9 3.6 5.5 5.9 3.9 3.9 2.8 3.8 5.3 21.6 7.2 0.6 4.3 13.9 2.7 0.7 41.0 102.2 0.6 27.2 1.1 13.7 1.6 1.1 31.9 11.4 0.6 0.6 49.4 1.5 6.7 2.1 13.1 15.5 5.9 5.5 5.0 6.3 5.3 6.3 7.1 6.5 7.7 6.2 7.5 6.3 19.6 0.0 1.1 74.1 40.9 8.9 0.3 0.0 0.6 1.4 0.8 1.5 10.1 0.0 0.7 1.8 2.1 0.6 3.7 0.3 1.9 0.0 10.3 0.6 3.6 60.6 0.0 4.4 2.8 2.0 1.9 15.7 6.1 0.6 3.8 0.3 31.4 0.8 26.6 0.0 5.2 0.1 0.0 110.4 161.3 7.3 0.6 62.1 16.0 217.4 112.2 0.4 0.0 20.6 5.0 0.2 1.2 3.0 80.1 0.5 0.1 0.3 0.8 0.8 6.6 1.0 22.7 10.1 4.4 0.8 11.2 15.7 26.9 15.1 1.0 0.5 EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 114.7;Hepatic stellate cells: 66.8;Hofbauer cells: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" 6.5 17.5 6.0 1.4 6.3 22.4 5.0 6.7 8.2 7.1 7.7 2.7 1.4 3.3 13.6 1.3 6.7 2.3 9.7 6.3 6.0 21.6 10.7 6.4 2.2 6.1 6.1 3.1 11.8 23.2 8.2 8.0 6.4 4.6 1.7 3.3 3.3 7.3 2.3 1.6 2.3 1.8 6.0 11.9 7.8 1.8 6.2 1.7 30.2 1.5 1.6 3.1 3.7 6.3 3.7 1.2 3.6 4.2 5.3 3.4 2.1 2.2 7.0 3.6 4.5 1.3 1.4 2.5 4.0 4.1 5.0 0.9 2.8 1.4 4.1 2.1 1.6 14.3 1.3 2.1 3.8 2.9 5.5 2.4 0.5 4.8 3.3 8.5 8.5 5.3 12.5 12.0 4.1 3.3 2.7 3.5 1.9 2.0 9.6 7.2 6.3 5.6 3.4 1.9 1.4 11.0 1.5 2.0 6.4 3.7 3.6 4.9 3.5 1.9 2.6 6.6 2.1 6.0 4.7 2.8 10.5 2.9 2.1 9.3 3.7 3.0 1.7 4.6 3.6 2.0 3.4 2.5 2.1 1.2 3.7 2.2 10.2 0.8 7.3 0.1 3.3 2.4 6.0 6.3 6.7 8.2 6.3 6.0 6.1 6.1 6.4 6.0 6.2 6.3 6.1 19.2 18.8 24.8 11.5 2.3 4.0 2.0 2.8 3.8 3.6 6.1 6.5 5.7 3.1 20.2 0.0 2.2 5.2 1.3 3.9 2.2 0.8 9.9 6.8 13.5 8.4 114.7 2.2 3.3 12.2 9.8 15.3 13.9 26.6 1.2 66.8 3.5 42.4 1.7 3.0 3.5 2.0 17.0 4.0 0.6 2.8 15.4 8.8 7.5 4.6 7.9 11.3 1.0 1.6 3.1 0.4 4.1 3.8 1.8 0.2 1.0 2.9 2.5 19.7 3.8 18.5 5.1 7.7 1.6 1.0 3.0 9.6 2.6 1.8 1.2 ERC2 "CAST, CAST1, ELKSL, KIAA0378, SPBC110, Spc110" ENSG00000187672 "ELKS/RAB6-interacting/CAST family member 2" O15083 3 55508311-56468467 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 11.7" "Group enriched" "Detected in some" 5 "Excitatory neurons: 818.5;Inhibitory neurons: 674.8;Oligodendrocyte precursor cells: 304.6" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Group enriched" "Detected in many" 32 "amygdala: 7.9;basal ganglia: 11.7;cerebral cortex: 11.1;hippocampal formation: 7.6;white matter: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.4;HUVEC TERT2: 2.1;Karpas-707: 7.9;SH-SY5Y: 2.0;U-266/70: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073739 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA073739: AB_2732240" "unprognostic (2.13e-2)" "unprognostic (1.39e-1)" "unprognostic (9.10e-2)" "unprognostic (1.93e-2)" "unprognostic (2.62e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-3)" "unprognostic (4.50e-2)" "unprognostic (2.95e-2)" "unprognostic (1.22e-1)" "unprognostic (3.06e-2)" "unprognostic (2.69e-1)" "unprognostic (1.75e-2)" "unprognostic (1.46e-2)" "unprognostic (1.24e-2)" "unprognostic (4.49e-2)" "unprognostic (9.09e-2)" 0.0 0.3 7.9 0.0 11.7 0.0 0.1 0.0 11.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 7.6 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.8 0.2 0.0 1.7 0.1 0.0 0.3 0.0 2.6 0.2 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 3.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 2.1 0.0 0.0 7.9 0.0 0.8 0.0 0.0 1.7 0.0 0.2 0.0 0.1 0.0 1.6 0.0 0.9 2.0 0.0 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.7 0.0 0.2 6.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 11.7 0.0 11.1 7.6 0.0 0.0 0.2 0.0 0.0 0.0 3.1 0.1 3.2 0.5 22.9 0.0 0.1 0.2 0.0 1.2 11.3 0.4 0.5 3.4 0.0 1.3 0.0 25.0 0.0 0.0 0.0 0.0 0.4 6.2 0.4 0.3 0.5 0.0 0.0 818.5 0.6 0.1 0.6 0.0 1.2 0.0 0.9 0.0 0.0 0.7 5.0 674.8 0.0 0.0 0.0 0.0 2.5 1.5 0.2 0.0 30.9 0.0 1.3 0.0 304.6 102.4 1.6 0.0 0.7 0.0 0.8 0.0 0.6 1.5 10.8 0.0 0.1 0.1 1.5 2.9 0.4 0.1 0.0 0.0 1.2 0.0 0.3 ERO1B "ERO1-L(beta), Ero1beta, ERO1LB" ENSG00000086619 "Endoplasmic reticulum oxidoreductase 1 beta" Q86YB8 1 236215101-236281958 "Predicted intracellular proteins" "Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 153.9" "Cell type enhanced" "Detected in many" "dendritic cells: 72.8;Early spermatids: 133.4;Spermatocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.4" "Group enriched" "Detected in all" 5 "dendritic cells: 6.0;granulocytes: 15.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028085 Enhanced "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA028085: AB_10601214" "unprognostic (1.16e-1)" "unprognostic (1.33e-3)" "unprognostic (1.00e-1)" "unprognostic (1.41e-1)" "unprognostic (1.07e-1)" "unprognostic (9.80e-2)" "unprognostic (2.49e-2)" "prognostic favorable (7.53e-5)" "unprognostic (1.73e-2)" "unprognostic (2.85e-2)" "unprognostic (4.65e-2)" "unprognostic (5.90e-2)" "unprognostic (8.26e-3)" "unprognostic (7.87e-2)" "unprognostic (3.37e-1)" "unprognostic (2.22e-3)" "unprognostic (8.09e-3)" 5.8 5.5 4.2 5.6 4.1 7.3 7.7 8.5 5.1 5.1 4.3 5.1 10.2 5.1 21.3 2.8 4.9 9.1 4.9 4.5 4.8 8.3 18.8 5.2 7.0 3.7 3.6 6.4 153.9 14.8 9.7 5.2 3.4 5.8 3.2 17.3 8.0 5.4 3.3 3.3 5.4 5.0 2.9 8.3 46.8 28.3 3.1 5.7 27.2 3.9 6.3 4.7 4.0 5.1 2.0 2.3 3.9 3.4 3.0 1.8 4.5 3.1 2.9 2.2 1.7 0.7 2.2 5.5 8.2 4.8 8.3 1.0 1.8 2.8 3.0 5.8 11.1 1.6 0.3 2.1 7.9 2.1 0.9 3.5 5.6 3.8 7.3 4.5 2.6 5.0 0.8 14.2 2.7 1.1 0.9 0.9 1.5 0.3 0.7 11.3 2.6 1.5 4.0 4.7 7.8 4.6 10.2 3.3 8.7 2.0 7.9 9.5 2.5 3.2 2.8 3.2 4.2 9.3 0.6 3.4 4.3 3.1 5.0 15.4 1.5 3.0 2.2 1.6 1.9 1.5 1.2 1.5 1.6 2.1 1.7 1.7 3.1 1.1 0.7 6.0 1.2 0.8 4.2 4.1 8.5 5.1 4.5 4.8 3.7 3.6 3.4 2.9 3.1 5.1 33.4 9.6 9.4 0.0 47.8 0.0 17.9 0.0 45.5 20.7 27.9 23.7 0.0 27.1 3.1 16.5 14.6 12.7 72.8 0.2 1.9 5.3 133.4 1.7 13.2 12.8 14.6 5.5 0.0 16.9 5.1 16.9 32.1 3.9 5.1 9.6 17.5 26.4 6.9 25.2 0.0 5.3 0.0 21.5 0.0 25.6 19.3 34.5 0.0 0.0 11.9 12.2 29.9 0.0 0.0 9.9 0.2 11.3 69.5 18.4 2.7 7.7 1.5 55.4 0.0 36.0 15.1 94.3 14.9 13.6 0.0 22.6 43.8 2.8 1.8 11.0 ETFDH ETFQO ENSG00000171503 "Electron transfer flavoprotein dehydrogenase" Q16134 4 158672125-158709623 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Disease variant, FDA approved drug targets, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 196.4;tongue: 186.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 146.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041978 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA041978: AB_10795605" "unprognostic (7.19e-2)" "unprognostic (2.28e-1)" "unprognostic (2.90e-2)" "unprognostic (5.92e-3)" "unprognostic (1.91e-1)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (7.17e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (1.71e-2)" "unprognostic (5.76e-2)" "prognostic favorable (5.76e-10)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (8.85e-3)" "unprognostic (1.74e-1)" 34.6 38.0 13.3 10.7 14.8 9.4 16.0 13.9 15.1 10.2 25.5 32.6 63.7 10.4 8.4 25.0 9.3 11.1 93.3 12.8 14.5 46.5 196.4 9.2 8.7 12.3 13.8 10.8 20.4 32.8 9.8 13.0 12.8 13.7 26.9 15.8 21.8 13.2 111.0 18.7 51.4 14.8 12.5 9.5 26.9 11.2 15.0 9.4 13.2 186.9 14.3 12.9 12.8 15.1 13.2 9.2 12.2 21.4 47.2 28.8 6.6 21.3 19.4 13.9 14.3 3.7 24.6 27.8 4.6 24.1 15.8 13.8 22.1 20.9 19.2 51.5 20.3 26.5 17.3 8.0 20.8 24.0 23.4 26.5 23.8 15.8 12.8 20.8 27.3 20.7 15.6 53.8 22.2 14.7 22.7 11.0 5.0 33.2 19.4 18.4 4.3 21.9 21.2 10.6 18.7 8.0 21.0 39.5 21.8 10.0 30.4 17.6 13.6 11.9 6.7 18.5 12.2 31.3 42.1 20.3 24.6 19.2 13.5 3.7 21.5 41.5 10.1 22.6 12.7 10.3 9.8 10.4 18.3 9.6 11.6 9.9 7.8 10.5 20.9 13.1 16.1 9.5 13.3 14.8 13.9 15.1 12.8 14.5 12.3 13.8 12.8 12.5 15.0 15.1 18.1 12.8 10.3 55.2 18.5 33.0 46.0 27.2 29.6 29.2 12.6 13.8 146.6 14.3 22.8 18.4 64.6 24.9 18.0 34.4 29.4 14.4 4.2 12.5 12.5 17.7 18.0 30.7 43.2 11.7 9.9 23.9 44.4 14.2 5.1 19.2 12.8 85.7 13.4 25.2 71.9 22.5 30.5 14.4 15.8 4.7 23.0 13.3 8.8 15.0 12.2 13.9 10.3 55.8 58.0 11.7 29.4 23.7 30.1 21.3 58.3 26.8 13.1 43.9 32.9 27.4 30.4 43.2 29.8 32.7 36.9 43.0 19.7 15.7 26.2 38.7 EXOC8 "EXO84, Exo84p, SEC84" ENSG00000116903 "Exocyst complex component 8" Q8IYI6 1 231332753-231337852 "Human disease related genes, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027438 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA027438: AB_1848318" "unprognostic (3.85e-2)" "unprognostic (6.52e-2)" "unprognostic (1.11e-1)" "unprognostic (2.05e-2)" "unprognostic (4.83e-2)" "unprognostic (5.82e-2)" "unprognostic (4.85e-2)" "unprognostic (1.55e-1)" "unprognostic (2.34e-1)" "unprognostic (2.69e-1)" "unprognostic (2.09e-2)" "unprognostic (1.74e-1)" "unprognostic (8.39e-2)" "unprognostic (1.77e-1)" "unprognostic (3.79e-2)" "unprognostic (2.21e-2)" "unprognostic (1.04e-1)" 6.1 5.4 3.0 7.9 3.1 16.9 6.7 4.8 3.9 5.2 2.9 5.0 5.9 4.5 4.8 5.5 4.8 5.0 5.2 3.3 4.2 5.9 6.2 5.9 9.2 3.1 2.7 7.0 6.3 8.7 2.9 6.5 3.4 5.5 4.7 7.5 5.4 3.8 14.1 5.9 6.3 4.4 2.5 8.3 6.8 4.1 3.7 7.4 8.4 9.8 9.1 5.3 3.7 3.7 8.2 9.0 5.4 5.4 13.9 11.2 13.0 10.0 8.4 7.4 7.0 8.6 8.1 9.4 8.6 10.1 6.6 13.2 7.9 10.8 8.1 12.2 19.0 5.7 11.8 5.5 7.8 10.1 15.2 11.3 11.7 11.0 10.4 8.7 9.2 9.6 10.6 21.9 12.0 4.3 9.4 6.2 8.2 10.4 7.6 6.1 8.3 12.0 9.3 9.5 7.1 7.6 10.1 13.1 10.1 4.3 12.5 14.5 12.6 9.9 7.0 13.3 17.7 16.2 9.9 10.1 11.3 8.9 12.7 1.7 0.7 1.3 0.4 0.8 0.5 0.4 0.6 0.5 0.5 0.5 0.7 1.2 2.2 0.8 1.6 0.7 0.6 0.5 3.0 3.1 4.8 3.9 3.3 4.2 3.1 2.7 3.4 2.5 3.7 3.7 10.0 9.6 9.8 2.0 10.9 18.5 5.6 4.0 8.0 4.3 8.1 5.5 8.9 11.5 8.3 9.2 6.2 4.6 10.4 6.7 1.9 3.3 1.6 8.1 9.0 9.3 4.8 7.4 5.3 3.5 2.8 8.2 14.3 10.4 2.5 4.3 6.8 9.6 5.8 3.3 5.9 3.7 2.0 13.3 7.1 1.1 4.1 7.6 3.6 3.7 5.7 5.8 5.2 2.5 6.6 5.0 1.2 5.7 7.9 6.0 6.9 5.2 5.6 12.3 0.0 8.4 5.2 5.1 5.0 11.0 14.8 9.3 10.0 4.6 4.2 8.6 EYS "bA166P24.2, bA307F22.3, bA74E24.1, C6orf178, C6orf179, C6orf180, dJ1018A4.2, dJ303F19.1, EGFL10, EGFL11, RP25, SPAM" ENSG00000188107 "Eyes shut homolog" Q5T1H1 6 63719980-65707226 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "retina: 24.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 316.9;Early spermatids: 87.3;Inhibitory neurons: 83.8;Late spermatids: 45.7;Rod photoreceptor cells: 140.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "Karpas-707: 1.5;SCLC-21H: 1.1" "Secreted in other tissues" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (2.92e-2)" "unprognostic (1.90e-2)" "unprognostic (1.64e-1)" "unprognostic (1.47e-2)" "unprognostic (2.16e-3)" "unprognostic (1.96e-1)" "unprognostic (1.82e-1)" "unprognostic (6.38e-2)" "unprognostic (3.67e-1)" "unprognostic (1.97e-1)" "unprognostic (2.04e-1)" "unprognostic (2.18e-1)" "unprognostic (2.61e-4)" "unprognostic (1.89e-1)" "unprognostic (8.41e-2)" "unprognostic (6.38e-3)" "unprognostic (1.11e-1)" 0.6 0.0 0.3 0.0 0.4 0.3 0.2 0.6 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.1 0.0 0.1 0.0 0.1 0.1 0.5 0.1 0.6 24.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 1.5 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.3 0.3 0.4 0.6 0.6 0.4 0.0 0.4 0.1 0.5 0.0 0.1 0.3 0.1 0.0 1.8 3.9 0.5 0.3 0.7 0.1 0.6 8.3 0.1 0.0 2.1 0.0 0.7 1.8 316.9 0.8 0.2 0.0 0.0 0.4 87.3 1.0 1.0 0.7 20.3 0.0 22.0 0.4 0.4 0.7 0.0 2.1 2.5 0.0 0.0 0.3 0.1 10.1 83.8 0.4 0.0 0.0 0.6 45.7 0.9 0.2 0.0 3.7 0.1 4.0 0.0 5.5 12.9 0.3 0.0 0.7 0.1 0.2 0.1 0.3 0.1 140.2 0.0 1.5 0.3 2.6 1.3 0.4 0.1 1.1 0.6 0.3 0.2 0.2 FAM171B "FLJ34104, KIAA1946" ENSG00000144369 "Family with sequence similarity 171 member B" Q6P995 2 186694060-186765959 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8" "Group enriched" "Detected in many" 5 "Astrocytes: 258.6;Bipolar cells: 141.4;Excitatory neurons: 126.5;Inhibitory neurons: 114.2;Oligodendrocyte precursor cells: 102.1;Oligodendrocytes: 78.5" "Cancer enriched" "Detected in many" 5 "glioma: 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 43.7;U-138 MG: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010639, HPA013434" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA010639: AB_1852447, HPA013434: AB_2262499" "unprognostic (2.52e-1)" "unprognostic (7.75e-3)" "unprognostic (1.27e-1)" "unprognostic (1.04e-2)" "unprognostic (4.03e-2)" "unprognostic (9.43e-2)" "unprognostic (6.78e-3)" "unprognostic (2.68e-1)" "unprognostic (1.88e-2)" "unprognostic (1.52e-1)" "unprognostic (4.24e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (9.51e-7)" "unprognostic (4.63e-3)" "unprognostic (1.52e-1)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.03e-4)" 2.9 14.4 36.1 1.5 52.2 0.5 3.4 8.3 54.8 6.6 0.0 1.8 1.0 7.5 2.1 1.9 2.7 4.9 1.4 52.8 33.0 1.2 0.3 1.4 1.2 15.0 16.9 10.2 1.0 7.6 10.7 3.3 17.6 2.7 2.0 24.1 23.0 2.3 0.7 3.7 1.4 4.4 17.2 1.5 2.0 0.9 28.3 2.8 2.2 3.6 1.1 2.2 2.2 30.1 4.2 4.9 7.2 22.6 20.9 15.7 0.1 4.5 8.0 5.5 7.8 13.6 21.9 0.0 1.6 12.9 9.3 0.5 9.9 4.3 7.8 0.0 5.7 5.1 2.1 0.0 1.6 1.5 1.7 20.2 1.8 4.2 3.4 7.1 12.1 3.9 0.0 43.7 10.5 2.9 3.0 0.0 9.6 0.0 4.9 0.0 13.9 1.0 8.5 15.8 22.4 12.2 2.3 1.4 6.1 4.2 1.7 1.0 7.1 29.7 3.9 0.5 2.9 11.5 12.0 0.0 9.2 0.0 4.2 0.2 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.4 0.2 0.2 0.0 0.0 36.1 52.2 8.3 54.8 52.8 33.0 15.0 16.9 17.6 17.2 28.3 30.1 9.1 0.0 0.0 258.6 0.1 8.9 2.8 1.2 4.0 141.4 10.7 5.7 0.8 5.7 5.7 0.0 14.6 11.4 0.5 0.0 0.0 1.0 1.3 1.5 13.0 14.4 4.8 1.3 126.5 0.4 0.8 14.1 2.6 4.7 0.0 0.8 6.8 0.1 2.0 23.5 114.2 0.0 4.1 0.3 2.8 4.0 7.8 1.0 3.6 18.7 0.7 16.2 0.0 102.1 78.5 0.7 0.0 13.9 0.2 1.4 0.0 0.2 2.6 17.0 0.0 8.6 4.5 0.4 1.5 0.6 5.3 8.2 0.9 2.6 0.0 1.1 FAM227A ENSG00000184949 "Family with sequence similarity 227 member A" F5H4B4 22 38578120-38656629 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 7.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6;Early spermatids: 87.3;Endometrial ciliated cells: 72.4;Late spermatids: 57.0;Respiratory ciliated cells: 115.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HDLM-2: 10.4;Karpas-707: 17.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003077 Uncertain Uncertain Nucleoplasm NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 2: Karpas-707 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA003077: AB_1079264" "unprognostic (7.52e-2)" "unprognostic (3.06e-2)" "unprognostic (1.63e-1)" "unprognostic (8.14e-2)" "unprognostic (5.85e-2)" "unprognostic (2.91e-3)" "unprognostic (4.79e-5)" "unprognostic (5.91e-2)" "unprognostic (3.04e-2)" "unprognostic (4.04e-2)" "unprognostic (1.85e-2)" "unprognostic (4.62e-2)" "unprognostic (6.46e-6)" "unprognostic (3.74e-1)" "unprognostic (3.47e-2)" "unprognostic (2.65e-3)" "unprognostic (1.35e-2)" 0.1 0.6 1.3 0.2 1.2 0.5 0.8 0.9 1.2 1.2 7.5 0.4 0.2 0.7 1.9 0.1 3.8 0.3 0.3 1.5 1.4 1.1 0.1 1.1 0.2 2.5 3.1 0.7 0.4 0.6 4.3 0.1 1.5 0.6 0.2 3.5 0.4 0.4 0.1 0.8 0.1 0.3 1.4 0.1 0.3 4.1 1.4 0.2 1.3 0.0 0.1 0.3 0.3 0.9 0.4 0.9 1.4 1.7 0.4 1.0 0.3 0.2 0.2 0.3 0.2 0.1 0.9 0.1 0.4 0.2 0.4 0.9 0.5 0.2 0.4 10.4 0.9 0.1 2.9 0.2 0.2 0.4 0.4 0.5 0.6 1.0 0.4 1.5 0.2 1.6 0.4 17.3 0.1 0.5 0.4 0.5 0.7 0.2 0.5 1.0 0.1 0.6 0.9 0.3 2.0 0.5 1.4 0.1 0.2 0.5 1.1 0.1 0.3 0.4 0.4 0.4 0.1 1.8 0.8 0.1 0.6 0.2 0.2 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 1.3 1.2 0.9 1.2 1.5 1.4 2.5 3.1 1.5 1.4 1.4 0.9 0.3 3.2 2.6 20.9 0.0 2.4 3.2 3.7 0.0 6.8 4.1 3.8 2.1 2.8 9.0 5.5 39.6 0.3 0.2 0.3 0.0 3.8 87.3 72.4 5.9 1.6 4.8 0.8 15.5 2.5 0.3 2.6 0.0 4.1 0.0 8.5 0.4 0.3 0.2 5.0 11.1 0.7 4.1 0.6 1.2 57.0 2.1 0.6 0.0 2.8 0.3 9.5 1.0 1.5 2.3 2.3 0.2 1.2 0.1 2.1 0.0 1.4 115.2 30.4 0.0 4.6 2.8 16.4 12.9 0.0 3.4 0.1 1.4 9.5 1.2 1.7 FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88990531-89017059 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 114.7" "Group enriched" "Detected in all" 5 "granulocytes: 114.7;T-cells: 96.2" "Cell line enhanced" "Detected in many" "HDLM-2: 83.4;Karpas-707: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11900000 420000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: AB_10601378" "unprognostic (6.84e-2)" "unprognostic (2.88e-3)" "unprognostic (8.38e-3)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (9.56e-2)" "unprognostic (7.00e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.32e-2)" "unprognostic (4.95e-3)" "unprognostic (1.65e-1)" 14.1 26.3 3.6 17.0 3.6 20.8 10.9 2.9 4.7 12.7 2.8 16.4 7.0 12.8 10.3 10.8 14.8 15.7 7.5 3.6 3.7 7.2 23.3 21.7 18.9 4.6 3.1 20.1 3.7 2.7 3.7 10.4 4.0 8.9 23.3 3.3 6.5 9.3 2.3 9.4 9.2 15.0 3.5 11.2 4.4 2.6 3.9 14.4 7.3 2.6 15.6 12.9 10.2 4.3 22.7 8.2 5.4 13.9 37.0 51.3 0.0 51.8 50.2 1.7 9.1 0.1 23.4 4.7 19.0 52.1 9.6 4.0 1.0 44.8 3.2 83.4 8.7 0.4 5.2 14.7 31.6 3.4 1.6 69.2 38.7 31.4 66.0 24.5 4.7 17.8 0.0 109.0 44.0 1.4 6.4 3.4 0.6 0.2 1.8 1.4 0.5 5.0 60.7 7.3 0.4 0.2 7.7 0.0 0.8 7.0 13.9 1.0 9.5 15.8 9.0 15.2 12.3 45.3 5.3 0.4 11.8 10.2 4.5 43.1 9.4 30.9 9.9 12.3 13.8 7.5 27.6 19.6 11.5 4.0 3.1 10.0 114.7 3.1 22.1 0.2 96.2 12.8 3.6 3.6 2.9 4.7 3.6 3.7 4.6 3.1 4.0 3.5 3.9 4.3 10.3 57.7 13.8 40.1 12.8 45.9 109.7 53.1 39.9 0.0 5.5 9.5 3.5 12.8 27.5 9.2 0.0 0.4 16.3 24.9 0.0 6.3 11.3 9.2 22.3 8.9 8.4 9.5 8.8 4.3 0.2 35.4 8.6 15.5 3.8 4.9 2.2 19.3 5.5 1.7 2.8 14.4 8.2 7.0 31.7 4.9 19.0 17.7 12.4 17.8 20.9 14.5 10.3 8.0 0.7 6.5 8.7 13.9 32.2 46.0 15.6 14.4 26.3 0.7 6.6 26.8 29.1 11.3 1.1 28.5 43.9 0.4 48.4 11.8 24.4 30.0 FBXL14 "Fbl14, MGC40195" ENSG00000171823 "F-box and leucine rich repeat protein 14" Q8N1E6 12 1565993-1594581 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 47.4;Late spermatids: 103.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 43.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053889 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" Cytosol "HPA053889: AB_2682293" "unprognostic (8.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.82e-1)" "unprognostic (4.00e-1)" "unprognostic (2.66e-1)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-3)" "unprognostic (3.77e-1)" "unprognostic (1.27e-1)" "unprognostic (5.90e-2)" "unprognostic (8.98e-2)" "prognostic favorable (9.04e-6)" "unprognostic (5.60e-3)" "unprognostic (1.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.12e-3)" 5.2 4.3 7.9 5.9 10.6 5.8 4.6 8.7 21.4 3.6 2.4 8.4 4.9 4.5 1.6 6.0 5.7 4.8 5.2 10.6 7.8 4.6 3.9 5.7 7.5 7.8 8.1 4.7 11.3 7.1 8.7 4.2 8.3 3.7 3.5 4.2 6.2 4.0 3.3 3.4 6.2 2.1 7.4 6.4 9.7 21.1 9.0 8.3 6.4 2.5 3.3 4.7 4.3 8.6 11.8 16.3 4.8 8.4 4.0 4.1 14.3 2.6 4.7 2.4 2.7 17.1 14.8 15.8 3.1 2.9 4.0 8.1 3.9 6.0 0.4 27.2 19.0 19.6 4.7 5.5 5.3 15.0 14.4 6.5 2.7 4.4 3.7 4.3 4.3 13.4 8.3 43.2 2.9 12.4 15.9 7.4 21.2 6.4 6.7 13.5 7.8 9.9 3.8 10.3 9.2 9.1 6.3 9.5 9.8 4.9 7.5 12.1 6.4 5.3 17.5 6.8 9.5 5.3 6.1 19.7 11.3 8.7 8.2 0.7 0.1 0.0 0.1 0.1 0.1 0.2 0.4 0.4 0.2 1.7 0.4 0.2 0.3 0.6 0.2 0.2 1.6 0.1 7.9 10.6 8.7 21.4 10.6 7.8 7.8 8.1 8.3 7.4 9.0 8.6 1.9 0.0 0.0 11.4 1.1 0.0 0.3 0.5 1.8 4.2 1.1 0.9 0.9 0.0 0.3 0.0 0.0 0.2 0.5 1.6 0.0 0.2 47.4 1.7 0.8 2.3 0.0 0.4 12.3 0.5 0.1 1.3 1.5 0.9 0.0 0.5 2.9 1.1 0.6 10.1 13.4 0.7 2.0 0.8 0.8 103.7 0.3 1.2 0.0 12.2 0.8 2.7 0.0 10.6 17.1 0.1 0.7 1.5 1.8 0.8 1.4 0.8 1.0 3.0 0.0 1.7 1.1 10.4 0.5 2.9 0.0 0.1 1.8 0.9 1.2 0.3 FBXO16 FBX16 ENSG00000214050 "F-box protein 16" Q8IX29 8 28348287-28490278 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 18.4;pituitary gland: 17.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Excitatory neurons: 44.4;Inhibitory neurons: 43.6;Rod photoreceptor cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 9.6" "Lineage enriched" "Detected in single" 10 "dendritic cells: 9.6" "Cell line enhanced" "Detected in many" "AF22: 20.3;Karpas-707: 22.4" "Low region specificity" "Detected in all" "HPA058676, HPA076472" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Plasma membrane, Cytosol" "HPA058676: AB_2683795, HPA076472: " "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" "unprognostic (3.37e-3)" "unprognostic (5.56e-3)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (2.55e-3)" "unprognostic (4.95e-3)" "unprognostic (6.49e-2)" "prognostic favorable (6.70e-5)" "unprognostic (3.41e-3)" "unprognostic (4.90e-2)" "unprognostic (7.15e-2)" "unprognostic (1.71e-2)" "unprognostic (4.85e-2)" "unprognostic (2.72e-2)" "unprognostic (2.07e-1)" 0.5 1.8 3.9 0.9 5.0 2.2 2.6 6.8 7.0 4.1 2.9 1.6 2.0 1.1 18.4 0.7 4.4 1.4 1.4 4.6 3.9 3.2 6.0 1.5 1.4 1.1 1.7 0.7 4.7 7.1 17.3 0.6 2.0 3.5 2.0 14.3 3.4 5.1 1.1 0.4 2.9 0.7 0.3 1.2 2.2 4.2 3.5 0.6 7.0 0.9 2.8 1.2 0.7 4.3 16.5 2.9 20.3 7.5 0.5 0.0 0.3 0.2 0.5 3.0 5.5 3.1 4.6 5.8 7.2 0.1 8.1 5.1 2.3 3.5 3.0 2.6 3.6 2.7 0.3 1.7 0.0 3.5 1.9 0.2 10.8 0.7 3.2 1.5 0.0 5.6 1.1 22.4 1.0 5.7 0.5 5.0 3.9 2.2 4.5 0.2 4.5 8.2 3.9 2.4 13.1 5.4 0.4 3.3 9.5 3.5 13.8 5.9 0.6 1.6 5.8 3.2 3.0 5.2 5.0 5.2 6.8 0.7 3.5 0.3 0.1 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.7 0.2 0.1 0.2 0.9 0.0 0.1 9.6 0.2 0.1 3.9 5.0 6.8 7.0 4.6 3.9 1.1 1.7 2.0 0.3 3.5 4.3 0.0 3.2 4.1 7.5 1.7 0.1 3.0 10.9 5.2 8.2 3.9 3.4 2.1 8.6 7.9 3.7 35.5 0.6 0.0 0.5 7.9 5.3 12.1 13.5 1.3 0.2 10.2 0.0 44.4 4.6 0.4 0.9 1.5 6.4 0.0 1.9 0.4 1.9 2.7 5.0 43.6 3.9 4.1 0.8 2.3 12.4 1.2 0.4 0.0 2.8 0.0 9.3 0.0 23.6 3.2 3.1 0.4 0.7 11.1 1.7 0.2 4.7 23.4 48.6 0.0 0.5 1.8 10.5 5.6 1.2 0.0 0.0 0.5 4.2 1.0 1.7 FBXO39 "CT144, Fbx39, MGC35179" ENSG00000177294 "F-box protein 39" Q8N4B4 17 6776215-6797101 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "testis: 30.3" "Group enriched" "Detected in some" 160 "Early spermatids: 346.2;Late spermatids: 553.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.16e-1)" "unprognostic (6.73e-2)" "unprognostic (1.69e-2)" "unprognostic (1.78e-2)" "unprognostic (2.15e-2)" "unprognostic (7.19e-2)" "unprognostic (7.93e-2)" "unprognostic (2.89e-1)" "unprognostic (3.30e-2)" "unprognostic (1.18e-1)" "unprognostic (1.72e-3)" "unprognostic (2.36e-1)" "unprognostic (3.73e-9)" "unprognostic (5.11e-2)" "unprognostic (2.67e-1)" "unprognostic (5.93e-2)" "unprognostic (3.79e-2)" 0.3 0.0 0.2 0.0 0.2 0.2 0.2 0.1 0.5 0.5 0.1 0.1 0.1 0.2 0.2 0.2 0.3 0.2 0.1 0.2 0.2 0.1 0.8 0.2 0.1 0.4 0.2 1.0 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 30.3 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.5 0.2 0.2 0.4 0.2 0.2 0.3 0.2 0.1 0.7 0.0 0.0 1.3 0.0 0.0 0.0 0.5 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.2 0.1 0.2 0.5 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 553.7 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 FBXO48 ENSG00000204923 "F-box protein 48" Q5FWF7 2 68459422-68467294 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Alveolar cells type 2: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA049775, HPA054782" Uncertain Approved "Nuclear bodies" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 54: Non-specific - Microtubule organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nuclear bodies" "HPA049775: AB_2680874, HPA054782: AB_2682599" "unprognostic (2.90e-1)" "unprognostic (2.62e-2)" "unprognostic (2.25e-1)" "unprognostic (2.75e-3)" "unprognostic (6.56e-3)" "unprognostic (2.90e-3)" "unprognostic (2.30e-1)" "unprognostic (4.74e-2)" "unprognostic (6.01e-3)" "unprognostic (3.92e-2)" "unprognostic (3.81e-2)" "unprognostic (2.33e-1)" "unprognostic (2.09e-2)" "unprognostic (6.42e-3)" "unprognostic (1.23e-1)" "unprognostic (3.39e-3)" "unprognostic (1.89e-2)" 1.1 1.2 1.3 1.4 1.8 0.7 1.3 1.5 1.5 1.1 1.2 1.1 1.8 0.8 1.1 1.1 0.7 0.8 0.7 1.3 1.2 1.4 2.0 1.0 1.7 1.5 1.4 1.7 0.8 1.3 0.5 1.2 1.7 0.8 1.2 3.0 1.3 0.7 3.1 2.5 1.5 0.6 1.2 1.8 1.3 1.0 1.7 1.2 1.1 1.8 1.8 0.7 0.9 2.7 2.1 0.7 1.3 0.9 1.6 1.8 0.9 1.5 1.8 1.4 1.6 1.0 0.9 2.6 1.0 0.7 1.9 1.1 1.2 1.2 2.7 3.5 1.3 1.3 0.7 0.5 0.7 0.6 1.5 0.8 2.1 2.0 1.7 0.7 0.6 4.3 0.6 4.9 1.1 0.4 1.5 1.9 0.7 1.4 1.0 1.3 2.3 1.7 1.1 0.6 1.3 0.9 0.7 0.3 1.7 1.1 0.4 0.6 0.6 1.6 1.5 2.0 1.6 3.9 2.5 1.1 1.0 1.1 1.2 2.6 0.7 0.9 1.0 0.7 1.0 0.9 1.7 1.0 0.4 1.0 1.2 1.2 1.4 1.0 1.3 0.9 2.1 0.6 1.3 1.8 1.5 1.5 1.3 1.2 1.5 1.4 1.7 1.2 1.7 2.7 9.1 32.1 52.0 1.3 6.4 7.1 5.0 3.1 9.1 3.9 7.7 10.4 11.7 7.2 16.3 5.5 2.1 4.2 4.5 7.1 11.7 3.2 1.7 4.0 3.1 8.2 3.0 4.0 0.8 3.3 3.5 6.8 3.1 4.1 12.6 2.1 5.3 7.1 4.1 3.3 0.8 6.2 0.0 5.1 6.6 1.0 4.1 8.7 1.8 0.0 2.5 2.2 2.1 1.5 1.7 3.1 2.7 1.5 5.8 3.4 7.4 9.2 12.9 5.7 0.0 5.5 3.9 18.0 11.1 6.7 8.0 1.6 8.1 2.8 3.5 3.9 FGD3 "FLJ00004, ZFYVE5" ENSG00000127084 "FYVE, RhoGEF and PH domain containing 3" Q5JSP0 9 92947523-93036236 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.4;lymphoid tissue: 32.4" "Cell type enhanced" "Detected in many" "dendritic cells: 41.8;Early spermatids: 66.1;Late spermatids: 99.0;NK-cells: 69.0;T-cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 43.9;Karpas-707: 61.4;RT4: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA020963, HPA021018" Approved Approved Nucleoplasm,Cytosol NA NA 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA020963: AB_2670542, HPA021018: AB_2670564" "unprognostic (5.66e-3)" "prognostic favorable (5.51e-4)" "unprognostic (5.05e-3)" "unprognostic (1.75e-2)" "unprognostic (1.14e-1)" "prognostic favorable (2.23e-7)" "unprognostic (2.26e-1)" "unprognostic (1.03e-2)" "unprognostic (2.61e-2)" "unprognostic (2.55e-1)" "unprognostic (2.68e-2)" "unprognostic (2.32e-1)" "unprognostic (8.56e-2)" "unprognostic (3.96e-1)" "unprognostic (1.60e-1)" "unprognostic (9.66e-2)" "unprognostic (1.22e-2)" 4.7 1.3 1.8 21.9 1.6 39.4 3.5 1.8 4.9 1.5 2.5 3.0 3.1 1.1 0.4 2.4 2.1 4.6 2.0 1.6 2.7 4.9 2.0 10.2 30.8 3.4 2.6 1.4 7.6 0.4 0.7 3.5 3.5 1.7 2.3 0.0 4.9 1.5 1.1 3.2 11.3 2.7 2.7 29.5 4.3 6.5 3.5 32.4 3.3 2.2 17.6 8.1 3.5 4.0 13.3 0.2 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 16.0 9.1 11.3 0.6 0.0 0.1 8.4 0.6 0.0 0.0 19.7 0.1 17.4 0.1 0.6 0.0 4.8 43.9 0.0 0.3 0.0 0.0 0.0 0.0 18.8 0.7 61.4 0.0 22.8 20.7 20.4 0.4 4.3 1.1 20.1 0.0 16.3 0.1 33.5 1.2 0.4 0.0 14.4 0.4 0.4 5.8 21.4 0.0 0.0 0.6 0.1 0.1 6.2 6.6 5.4 3.1 10.3 0.0 142.9 50.6 139.6 49.5 63.4 49.9 28.6 51.4 46.6 37.5 36.9 50.1 44.7 178.2 39.1 99.2 16.8 48.4 74.0 1.8 1.6 1.8 4.9 1.6 2.7 3.4 2.6 3.5 2.7 3.5 4.0 1.7 22.4 9.2 0.0 25.3 0.8 0.6 0.4 0.6 0.1 5.8 1.8 2.5 4.3 2.3 9.2 0.0 2.9 41.8 0.4 0.0 7.2 66.1 1.2 0.2 2.1 1.8 11.8 0.6 0.2 3.2 0.9 0.0 0.6 19.6 3.7 1.8 0.8 15.5 0.0 1.6 0.6 0.0 22.3 6.2 99.0 0.3 20.7 1.8 12.2 20.1 0.4 69.0 5.0 0.5 0.4 0.1 0.4 15.8 0.1 0.0 0.7 0.3 3.9 0.0 0.3 0.8 1.6 2.4 0.5 1.0 4.5 47.3 0.1 0.4 0.5 FOXO3 "AF6q21, FKHRL1, FOXO2, FOXO3A" ENSG00000118689 "Forkhead box O3" O43524 6 108559835-108684774 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 94.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004074, HPA063104" Supported Enhanced Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB004074: AB_2106672, HPA063104: AB_2684941" "unprognostic (3.42e-2)" "unprognostic (3.76e-2)" "unprognostic (4.28e-2)" "unprognostic (1.96e-2)" "unprognostic (6.68e-2)" "unprognostic (4.63e-2)" "unprognostic (4.08e-3)" "unprognostic (1.73e-1)" "unprognostic (3.81e-2)" "unprognostic (5.18e-2)" "unprognostic (1.98e-2)" "unprognostic (1.75e-1)" "unprognostic (2.54e-2)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "unprognostic (5.81e-2)" "unprognostic (5.68e-2)" 46.7 11.4 14.7 13.4 15.1 68.5 43.1 34.0 19.6 28.1 19.3 21.7 12.4 23.5 15.3 35.4 25.4 28.2 18.6 14.3 9.8 16.3 23.1 30.3 12.8 17.4 15.5 43.0 86.9 30.2 8.6 21.3 13.3 20.0 17.0 28.7 25.1 11.5 84.1 30.6 16.9 21.1 11.5 18.8 22.2 11.9 17.1 18.5 18.0 51.4 15.8 23.2 27.4 17.0 21.6 6.8 9.1 20.4 41.2 48.4 16.1 17.0 17.7 13.5 19.9 11.9 19.5 11.7 14.8 20.0 22.3 15.0 12.1 20.8 20.4 12.9 18.3 32.5 6.2 9.8 47.4 8.6 24.8 56.0 43.2 29.3 40.4 19.8 10.3 10.2 21.8 94.5 26.9 12.2 9.4 12.6 6.1 10.1 11.6 12.1 32.4 48.7 30.7 16.5 23.4 59.9 12.7 11.8 16.6 18.1 12.1 27.7 18.3 24.9 12.9 13.8 20.6 0.9 16.8 13.5 13.4 16.2 16.4 7.8 2.8 6.1 3.2 1.5 3.8 0.8 1.7 2.6 1.7 1.7 1.4 2.0 15.6 3.7 5.3 2.7 1.9 1.1 14.7 15.1 34.0 19.6 14.3 9.8 17.4 15.5 13.3 11.5 17.1 17.0 88.2 44.8 46.0 112.6 41.2 67.7 73.3 34.4 91.6 63.4 64.1 46.9 31.6 71.4 44.4 25.8 70.9 25.4 41.4 86.9 17.6 50.4 19.9 91.2 41.8 55.6 66.9 246.9 102.7 30.9 36.9 105.8 46.9 105.6 15.2 46.2 84.6 77.7 46.4 52.2 99.9 55.0 20.3 85.2 83.3 17.7 106.6 96.6 56.9 160.2 55.9 78.9 22.6 108.6 133.2 73.3 44.2 100.4 83.3 122.2 28.3 21.1 57.7 68.6 32.9 236.6 81.6 9.1 17.8 61.1 46.5 41.2 37.6 30.6 34.5 184.2 FSTL5 "DKFZp566D234, KIAA1263" ENSG00000168843 "Follistatin like 5" Q8N475 4 161383897-162164004 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 68.6;retina: 94.8" "Group enriched" "Detected in some" 4 "Bipolar cells: 306.0;Cone photoreceptor cells: 462.9;Excitatory neurons: 184.7;Inhibitory neurons: 517.7;Rod photoreceptor cells: 139.6" "Cancer enriched" "Detected in single" 6 "melanoma: 1.7" "Region enriched" "Detected in all" 5 "cerebellum: 68.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 75.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 57.3" "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (4.90e-2)" "unprognostic (4.46e-1)" "unprognostic (1.52e-2)" "unprognostic (2.03e-1)" "unprognostic (3.66e-2)" "unprognostic (2.99e-2)" "unprognostic (3.00e-1)" "unprognostic (2.05e-2)" "unprognostic (1.10e-1)" "unprognostic (3.39e-2)" "unprognostic (1.61e-1)" "unprognostic (1.08e-10)" "unprognostic (8.45e-4)" "unprognostic (1.53e-1)" "unprognostic (1.52e-1)" "unprognostic (6.60e-3)" 0.0 6.0 7.4 0.0 6.9 0.0 0.0 68.6 3.7 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.1 15.2 0.0 0.0 0.0 0.0 12.7 9.9 0.0 0.3 0.0 1.2 0.1 14.4 0.0 0.1 94.8 0.0 0.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.6 9.6 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 2.1 0.0 0.9 0.0 0.0 0.0 12.4 0.1 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 75.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 10.8 0.0 0.0 0.7 0.1 0.0 0.3 0.1 0.0 0.0 16.2 0.0 6.2 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 6.9 68.6 3.7 3.1 15.2 12.7 9.9 14.4 6.2 9.6 5.1 0.0 0.0 0.0 47.7 0.0 0.3 0.0 0.0 0.0 306.0 0.0 0.0 0.1 0.0 0.0 0.0 462.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.8 0.0 0.0 184.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 28.6 517.7 0.0 0.0 0.3 0.3 4.5 0.6 0.0 1.8 7.5 0.0 20.7 0.0 8.0 75.3 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.0 139.6 0.0 0.0 0.0 0.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FXYD5 OIT2 ENSG00000089327 "FXYD domain containing ion transport regulator 5" Q96DB9 19 35154730-35169881 "Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 462.9;Hofbauer cells: 430.3;Langerhans cells: 492.1;Pancreatic endocrine cells: 585.0;T-cells: 459.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010817 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "HPA010817: AB_1849214" "unprognostic (3.97e-3)" "unprognostic (5.49e-2)" "unprognostic (6.37e-3)" "unprognostic (3.01e-1)" "unprognostic (2.50e-3)" "unprognostic (4.39e-3)" "unprognostic (4.68e-2)" "unprognostic (1.56e-3)" "unprognostic (3.85e-1)" "unprognostic (5.66e-3)" "unprognostic (4.78e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.71e-9)" "unprognostic (6.07e-2)" "unprognostic (7.88e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" 203.1 39.2 30.8 130.8 31.0 275.2 171.1 31.9 47.2 226.2 36.9 59.0 28.6 75.5 20.1 116.1 103.6 68.8 82.3 29.9 36.6 42.0 40.2 148.5 187.4 43.4 34.7 28.6 28.0 17.2 39.8 91.7 37.9 68.8 43.3 3.5 70.3 46.5 28.6 85.8 106.6 59.8 35.4 238.3 67.9 9.2 40.0 85.0 59.2 32.6 187.8 104.8 183.8 39.9 932.2 216.7 0.2 0.9 310.5 390.2 213.6 521.7 686.4 362.8 269.3 61.9 263.6 212.9 139.3 632.2 130.3 212.3 132.5 321.3 231.4 265.7 87.9 397.7 111.8 0.5 244.3 228.6 378.0 233.6 141.6 265.3 452.2 213.2 348.5 58.0 380.0 989.0 229.5 1.5 27.4 95.1 66.4 853.4 126.0 127.6 45.0 272.7 134.0 5.2 38.8 0.3 287.1 148.6 316.6 115.0 78.0 180.4 494.8 443.6 170.0 487.7 40.2 1.5 16.2 54.4 675.9 524.8 694.4 644.0 596.4 111.1 451.5 628.4 422.0 602.8 756.5 467.4 718.7 545.6 489.2 405.6 140.1 840.8 636.9 325.0 894.6 934.1 30.8 31.0 31.9 47.2 29.9 36.6 43.4 34.7 37.9 35.4 40.0 39.9 291.0 3.2 13.4 0.0 330.7 107.1 73.4 106.3 54.1 0.6 80.2 51.2 5.2 32.9 27.8 99.3 0.0 18.9 349.7 2.9 0.0 156.1 1.7 3.4 63.5 276.5 10.7 111.2 2.2 197.3 462.9 93.1 71.9 2.2 361.5 0.3 323.8 6.1 430.3 0.0 0.4 8.2 4.1 385.9 492.1 4.6 6.5 403.9 209.9 10.3 243.7 0.4 260.6 1.0 0.1 585.0 7.8 0.7 302.5 72.2 0.2 4.4 5.5 0.4 65.7 5.7 107.6 1.6 8.1 24.0 69.2 50.9 459.5 0.7 10.0 100.3 GABRA3 ENSG00000011677 "Gamma-aminobutyric acid type A receptor subunit alpha3" P34903 X 152166234-152451315 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 15.5;choroid plexus: 16.3;retina: 9.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 70.3;Hofbauer cells: 16.2;Inhibitory neurons: 22.2;Oligodendrocyte precursor cells: 58.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 16.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 9.9;HMC-1: 8.4;Karpas-707: 14.4;PC-3: 8.4;U-266/70: 7.7;U-266/84: 13.6;U-87 MG: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000839, HPA029363" Approved Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA000839: AB_1078929, HPA029363: " "unprognostic (9.63e-3)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.18e-2)" "unprognostic (7.07e-2)" "unprognostic (5.42e-2)" "unprognostic (2.34e-6)" "unprognostic (1.24e-1)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" "unprognostic (2.63e-2)" "unprognostic (1.73e-1)" "unprognostic (7.29e-6)" "unprognostic (7.42e-3)" "unprognostic (6.20e-2)" "unprognostic (8.13e-2)" 0.0 0.0 10.0 0.0 13.7 0.0 0.0 0.0 13.2 0.9 16.3 0.1 0.1 0.3 0.0 0.4 0.0 0.0 0.0 9.6 15.5 0.0 0.0 0.0 0.0 0.9 4.0 0.0 0.0 0.0 0.6 2.9 3.0 0.1 0.0 9.0 0.1 0.6 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.7 11.2 0.0 0.0 0.0 0.1 0.4 0.2 2.7 0.0 0.8 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 14.4 0.0 0.0 0.0 0.0 2.6 6.4 8.4 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.0 5.3 0.4 0.3 0.1 1.3 0.1 5.3 7.0 0.3 1.6 7.7 13.6 0.0 8.4 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 13.7 0.0 13.2 9.6 15.5 0.9 4.0 3.0 0.6 11.2 2.7 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 0.6 1.2 0.0 0.0 0.3 0.0 0.0 0.0 2.1 3.2 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.1 0.0 0.0 70.3 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 16.2 1.7 22.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 3.0 0.0 58.3 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 1.2 0.9 0.0 1.9 0.0 0.0 0.0 0.5 GADL1 ENSG00000144644 "Glutamate decarboxylase like 1" Q6ZQY3 3 30726200-30894765 "Enzymes, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "skeletal muscle: 25.8;tongue: 11.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.4;Club cells: 1.3;Collecting duct cells: 1.8;Fibroblasts: 5.9;Late spermatids: 1.8;Skeletal myocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 4.7;TIME: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039160, HPA040229" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA039160: AB_10796222, HPA040229: AB_10796118" "unprognostic (4.96e-2)" "unprognostic (1.30e-2)" "unprognostic (9.83e-2)" "unprognostic (1.39e-2)" "unprognostic (5.60e-2)" "unprognostic (7.32e-2)" "unprognostic (5.05e-3)" "unprognostic (8.37e-2)" "unprognostic (1.23e-2)" "unprognostic (2.02e-3)" "unprognostic (1.63e-1)" "unprognostic (1.98e-5)" "unprognostic (8.81e-2)" "unprognostic (4.54e-2)" "unprognostic (4.39e-1)" "unprognostic (1.06e-1)" 0.3 0.4 2.2 0.4 2.1 1.2 0.4 2.6 2.5 0.1 0.1 0.2 0.2 0.3 0.6 0.6 0.2 0.3 0.6 1.8 0.8 0.7 0.3 0.3 0.4 0.9 0.5 0.6 0.4 0.2 0.2 0.3 0.9 0.6 0.2 1.7 0.4 0.1 25.8 0.9 0.2 0.2 0.1 0.6 0.3 0.5 1.0 0.1 0.9 11.3 0.3 0.2 0.0 2.3 0.4 0.0 0.2 0.4 0.3 0.1 0.5 0.2 0.1 0.0 0.0 0.5 0.5 0.4 0.2 0.0 0.2 0.3 4.7 0.1 0.1 0.6 0.1 0.5 0.8 0.2 0.0 0.3 1.3 0.1 0.1 0.2 0.1 0.4 0.1 0.3 0.5 1.7 0.2 0.3 0.2 0.5 0.5 0.1 0.1 0.7 0.9 0.4 0.2 0.6 0.5 0.3 0.2 0.3 1.3 0.3 0.4 0.3 2.4 0.6 0.5 0.8 0.2 0.6 0.3 0.3 0.2 0.2 0.6 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.0 2.2 2.1 2.6 2.5 1.8 0.8 0.9 0.5 0.9 0.1 1.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.6 0.0 1.3 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.3 0.0 0.0 0.5 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.3 1.8 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.6 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" Q9NY28 12 4720400-4851927 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 31.3;testis: 13.5" "Group enriched" "Detected in some" 6 "Early spermatids: 95.2;Intestinal goblet cells: 47.0;Late spermatids: 150.2" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.2;glioma: 1.8;pancreatic cancer: 0.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 23.4;U-266/84: 7.6" "Not detected" "Not detected" "HPA012638, HPA073461" Supported Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA No "Cluster 22: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA012638: AB_2294503, HPA073461: AB_2686604" "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (1.75e-2)" "unprognostic (6.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (5.76e-2)" "unprognostic (8.06e-5)" "unprognostic (1.16e-2)" "unprognostic (6.67e-5)" "unprognostic (5.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-2)" 0.4 0.6 3.2 1.8 3.3 0.0 0.6 2.7 5.1 0.5 2.0 14.0 5.7 0.3 0.1 0.1 0.6 0.0 2.5 3.2 2.8 0.4 0.2 0.3 0.2 3.4 3.2 0.7 0.2 0.0 2.8 0.1 3.3 0.4 31.3 0.2 0.4 0.3 0.1 0.2 12.6 0.8 2.9 0.5 0.5 13.5 3.3 0.0 0.2 0.0 0.0 0.4 0.3 4.1 0.0 0.0 0.5 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 23.4 0.0 0.0 0.0 0.1 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 3.2 3.3 2.7 5.1 3.2 2.8 3.4 3.2 3.3 2.9 3.3 4.1 0.1 6.4 0.5 1.3 0.5 0.0 0.0 0.1 0.6 2.1 0.1 2.3 4.5 0.0 0.0 0.0 0.0 0.0 1.5 1.8 0.0 0.0 95.2 0.5 0.1 0.5 6.6 0.0 1.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 47.0 0.0 0.0 0.0 150.2 1.5 0.1 0.0 3.7 0.2 0.5 0.0 15.1 7.4 0.2 0.6 2.6 0.0 0.1 1.0 1.0 0.0 0.6 6.6 0.7 0.1 12.3 8.3 0.0 0.0 0.0 0.8 0.3 2.2 0.0 GAS2 ENSG00000148935 "Growth arrest specific 2" O43903 11 22625509-22813055 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell shape, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 39.7" "Group enriched" "Detected in some" 4 "Astrocytes: 39.8;Excitatory neurons: 114.9;Inhibitory neurons: 141.9;Oligodendrocytes: 83.9" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Hep G2: 43.2;JURKAT: 24.0;Karpas-707: 85.2;SCLC-21H: 24.8;U-266/84: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058904 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" Yes NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "HPA058904: AB_2683850" "unprognostic (5.48e-3)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (1.16e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.30e-5)" "prognostic favorable (6.13e-4)" "unprognostic (5.85e-2)" "unprognostic (4.22e-2)" "unprognostic (7.94e-2)" "unprognostic (3.58e-2)" 0.4 0.8 2.1 0.3 1.9 0.1 0.8 4.5 5.4 0.9 0.0 0.7 1.8 0.8 0.0 0.7 1.2 1.6 3.5 0.7 2.2 5.4 39.7 1.0 1.0 6.2 7.5 2.0 9.6 0.1 2.5 0.4 6.3 1.0 0.4 2.2 1.5 0.6 4.6 0.8 1.6 0.3 3.3 1.3 2.6 0.8 6.1 8.2 0.8 1.8 0.7 1.0 0.7 6.1 0.0 0.1 1.7 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.7 0.4 0.2 0.0 43.2 0.5 0.1 0.3 0.1 0.1 0.0 0.2 0.3 0.0 24.0 1.6 85.2 0.0 0.4 0.3 0.1 0.3 2.4 0.0 0.9 0.5 4.4 0.0 1.1 24.8 1.3 0.0 0.0 0.5 0.2 0.1 0.0 1.8 0.0 0.4 1.1 0.0 1.1 30.7 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 1.9 4.5 5.4 0.7 2.2 6.2 7.5 6.3 3.3 6.1 6.1 0.1 0.0 0.0 39.8 0.4 0.1 0.4 0.1 0.6 1.9 0.4 0.1 12.7 10.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 2.3 1.3 0.1 0.4 0.0 0.0 114.9 3.3 0.0 1.0 3.1 0.7 0.0 0.2 0.7 22.9 0.0 0.0 141.9 0.6 0.0 0.0 0.0 5.4 0.6 0.0 0.0 9.4 0.2 0.2 0.0 18.6 83.9 1.6 1.4 0.0 0.5 0.1 0.1 3.2 4.0 1.2 0.0 0.3 0.8 0.4 1.1 0.6 0.0 0.0 0.4 0.1 0.9 0.3 GGH ENSG00000137563 "Gamma-glutamyl hydrolase" Q92820 8 63014881-63039407 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 125.7;liver: 188.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 510.3;Early spermatids: 471.0;Extravillous trophoblasts: 273.4;Proximal tubular cells: 340.8;Syncytiotrophoblasts: 754.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 30.6" "Lineage enriched" "Detected in all" 5 "dendritic cells: 30.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019296, HPA025226" Approved "Intracellular and membrane" NA NA 1200000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB019296: , HPA025226: AB_1849645" "unprognostic (9.29e-2)" "unprognostic (1.22e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.99e-7)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (1.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.11e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-2)" "unprognostic (9.62e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (6.50e-2)" 9.8 5.4 11.1 14.2 11.1 43.7 16.5 10.7 14.3 5.9 13.1 54.3 11.3 6.3 4.4 20.7 3.5 4.3 3.1 11.1 12.3 125.7 188.6 8.0 10.9 13.3 11.1 3.1 9.9 13.1 1.9 54.9 13.7 4.4 74.4 2.1 13.0 3.7 2.1 27.2 9.9 11.6 10.1 5.5 8.2 33.9 14.4 17.8 2.4 3.2 22.5 8.5 10.8 11.1 110.5 97.6 97.4 15.7 94.1 39.6 69.6 64.3 105.1 94.2 137.7 144.5 183.8 69.8 18.0 77.1 166.8 87.2 97.2 101.9 138.9 139.0 71.6 112.3 50.3 105.1 17.6 53.5 65.9 29.1 29.2 93.9 50.7 59.4 116.1 66.9 62.4 255.2 177.3 64.3 28.8 71.1 51.0 231.6 86.0 77.6 95.2 98.1 75.8 40.3 38.6 69.9 91.8 103.6 98.5 91.6 116.6 65.8 65.5 104.2 115.6 99.4 111.3 112.6 127.2 88.3 158.0 0.1 185.0 0.0 2.1 2.3 1.1 1.7 0.8 6.5 1.5 1.7 0.9 2.7 1.8 1.9 3.0 4.4 2.0 30.6 2.7 1.9 11.1 11.1 10.7 14.3 11.1 12.3 13.3 11.1 13.7 10.1 14.4 11.1 13.1 16.0 7.3 11.1 26.1 30.2 23.2 66.6 9.1 2.0 14.9 21.0 3.2 17.2 31.1 22.0 0.0 510.3 11.7 49.2 37.2 19.7 471.0 5.4 11.5 13.1 13.2 62.5 11.5 7.4 273.4 27.2 11.7 7.6 10.8 21.4 13.6 219.5 72.4 0.0 8.7 70.7 44.7 21.0 15.5 154.2 5.9 12.0 24.9 1.0 32.1 23.1 2.1 3.5 2.9 4.3 23.7 8.2 106.9 10.5 4.3 340.8 18.3 1.3 26.3 12.8 20.4 80.3 133.0 35.9 43.0 754.5 8.5 9.3 102.0 23.1 GHRL "ghrelin, MTLRP, obestatin" ENSG00000157017 "Ghrelin and obestatin prepropeptide" Q9UBU3 3 10285666-10292947 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "stomach 1: 356.1" "Cell type enriched" "Detected in many" 52 "Gastric mucus-secreting cells: 1123.8" "Cancer enhanced" "Detected in some" "stomach cancer: 3.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 17.5;classical monocyte: 11.0;eosinophil: 12.4;myeloid DC: 41.8;neutrophil: 25.7;plasmacytoid DC: 28.5" "Group enriched" "Detected in many" 6 "dendritic cells: 41.8;granulocytes: 25.7;monocytes: 11.0" "Cell line enhanced" "Detected in many" "Karpas-707: 14.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA014246, CAB022731" Enhanced "Secreted to blood" NA NA 2580000 350000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB022731: , HPA014246: AB_1849659" "unprognostic (1.74e-2)" "unprognostic (3.01e-4)" "unprognostic (3.75e-1)" "unprognostic (1.05e-2)" "unprognostic (2.94e-2)" "unprognostic (1.60e-3)" "unprognostic (2.12e-1)" "unprognostic (1.06e-3)" "unprognostic (3.85e-1)" "unprognostic (5.45e-3)" "unprognostic (1.54e-3)" "unprognostic (2.71e-2)" "unprognostic (1.64e-3)" "unprognostic (4.52e-2)" "unprognostic (8.56e-2)" "unprognostic (2.14e-1)" "unprognostic (1.79e-4)" 0.5 0.5 3.5 3.1 4.1 4.4 1.5 4.0 7.6 0.5 3.0 2.2 19.0 0.7 4.8 1.8 0.7 2.3 1.3 3.3 2.8 0.9 1.4 1.0 7.4 3.2 2.8 1.3 4.1 0.7 0.7 0.5 3.5 1.0 0.6 2.0 1.4 0.3 2.0 2.1 3.1 0.9 2.0 2.5 356.1 1.1 2.7 1.3 1.3 0.2 3.1 1.4 0.5 2.9 0.6 0.2 2.6 2.0 1.8 0.0 4.8 2.4 0.0 0.7 0.2 2.9 0.5 1.5 0.9 0.1 2.1 0.4 0.0 0.6 0.0 0.4 2.9 3.1 2.1 6.3 0.0 3.2 5.3 0.3 0.0 0.0 0.1 0.2 0.5 1.9 1.3 14.4 0.0 0.7 1.2 4.3 1.3 0.5 5.3 0.8 0.2 0.8 0.0 2.4 1.9 0.3 1.6 1.1 0.1 1.7 1.1 3.8 2.6 1.2 0.7 1.1 1.7 1.7 2.6 2.9 0.4 3.5 0.5 17.5 11.0 12.4 0.2 5.5 0.1 2.1 0.2 0.0 41.8 1.0 0.3 0.1 25.7 4.4 0.4 28.5 0.2 3.8 3.5 4.1 4.0 7.6 3.3 2.8 3.2 2.8 3.5 2.0 2.7 2.9 0.6 0.0 1.1 1.3 4.9 1.3 4.6 0.2 0.0 7.8 0.8 0.6 0.3 0.0 0.2 1.8 10.4 1.7 10.5 0.5 0.0 1.0 0.3 0.2 0.7 1.5 0.0 0.0 1.0 1.3 1.5 1.0 1123.8 0.8 0.0 0.6 1.8 0.1 1.8 3.3 0.6 0.1 0.0 3.8 8.8 1.0 0.3 5.7 1.8 2.8 7.4 2.2 21.6 0.0 0.7 0.9 0.1 0.4 0.7 4.9 1.5 0.2 0.2 9.1 6.6 4.0 0.9 1.7 1.3 0.0 0.6 0.3 4.0 0.7 0.8 2.2 GLRA3 ENSG00000145451 "Glycine receptor alpha 3" O75311 4 174636920-174829247 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 10.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 25.3;Early spermatids: 24.7;Excitatory neurons: 52.4;Inhibitory neurons: 11.2;Late spermatids: 22.8" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.75e-3)" "unprognostic (3.14e-1)" "unprognostic (1.78e-2)" "unprognostic (1.36e-1)" "unprognostic (9.02e-2)" "unprognostic (3.82e-2)" "unprognostic (2.37e-1)" "unprognostic (1.22e-1)" "unprognostic (1.12e-2)" "unprognostic (4.26e-2)" "unprognostic (1.64e-5)" "unprognostic (4.61e-4)" "unprognostic (2.24e-1)" "unprognostic (1.15e-2)" 0.0 0.8 4.2 0.0 3.4 0.0 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.5 0.0 0.0 0.0 0.2 0.8 3.6 0.0 0.4 0.0 0.6 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.5 10.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.2 3.4 0.0 3.0 2.6 4.5 0.8 3.6 0.6 0.9 10.5 0.0 0.0 0.0 0.6 1.3 1.6 0.0 1.3 0.0 0.0 5.0 25.3 0.3 2.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 0.1 0.4 0.0 0.0 52.4 0.0 0.0 1.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 22.8 0.0 0.1 0.0 2.8 0.0 0.2 0.0 1.0 1.0 0.2 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.6 0.0 1.0 0.3 0.7 1.6 0.1 0.1 0.0 0.3 0.0 0.0 0.4 GPATCH11 "CCDC75, CENP-Y, CENPY, FLJ38348" ENSG00000152133 "G-patch domain containing 11" Q8N954 2 37084451-37099244 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038231, HPA038232" Enhanced Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA038231: AB_2675904, HPA038232: AB_10675788" "unprognostic (1.28e-2)" "unprognostic (1.58e-1)" "unprognostic (2.45e-1)" "unprognostic (1.80e-1)" "unprognostic (3.88e-2)" "unprognostic (2.23e-2)" "unprognostic (4.58e-3)" "unprognostic (2.40e-2)" "unprognostic (2.44e-2)" "unprognostic (4.39e-2)" "unprognostic (1.16e-1)" "unprognostic (1.26e-1)" "unprognostic (8.64e-3)" "unprognostic (4.31e-2)" "unprognostic (4.44e-2)" "unprognostic (3.40e-2)" "unprognostic (7.16e-2)" 23.0 6.3 7.5 7.8 8.5 10.0 6.9 8.8 9.9 7.0 6.0 4.5 4.8 4.8 3.7 5.1 3.7 4.4 5.4 7.7 8.8 5.5 5.7 6.3 12.7 8.3 8.0 5.9 3.0 5.5 3.5 5.7 8.5 4.0 4.9 21.0 3.7 4.1 2.4 5.9 5.0 4.3 8.5 8.0 4.8 11.6 8.0 10.3 6.4 5.4 11.7 5.2 3.1 10.4 12.5 7.4 12.4 9.7 25.7 11.9 13.2 22.1 8.9 13.1 10.7 9.4 5.2 14.4 12.1 8.3 11.4 8.8 14.8 5.3 19.5 24.7 16.1 26.3 9.8 9.6 8.3 31.7 27.5 7.8 9.4 18.0 10.1 8.6 11.6 9.0 25.0 65.8 15.4 6.3 20.6 17.4 5.3 20.5 10.3 16.9 26.4 40.7 5.7 5.3 14.9 13.9 11.6 7.4 11.2 9.9 7.6 14.6 12.9 23.7 13.1 17.4 24.7 25.6 28.2 21.6 16.9 26.2 21.3 5.9 2.4 2.2 4.4 2.0 4.4 8.7 3.2 3.7 3.6 6.8 3.4 3.5 0.8 6.7 0.7 12.2 2.6 1.5 7.5 8.5 8.8 9.9 7.7 8.8 8.3 8.0 8.5 8.5 8.0 10.4 14.7 12.8 8.1 3.9 23.3 4.2 2.7 5.7 7.4 24.3 6.2 7.0 14.1 8.6 5.0 11.0 25.0 8.8 48.7 12.1 11.7 9.3 32.9 12.6 20.0 12.8 3.0 22.1 14.3 14.1 30.5 12.2 8.6 13.9 12.0 8.7 17.9 15.0 13.4 13.5 12.1 9.1 6.1 18.8 15.0 10.5 16.1 21.1 3.6 5.6 12.7 28.9 22.6 10.6 12.5 14.8 4.9 22.2 23.2 1.6 9.7 13.2 11.5 52.7 13.1 13.4 21.7 75.5 43.6 7.8 5.4 3.8 16.8 13.7 6.0 2.0 GPBP1 DKFZp761C169 ENSG00000062194 "GC-rich promoter binding protein 1" Q86WP2 5 57173948-57264679 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 622.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037773 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cytosol" "Plasma membrane" "HPA037773: AB_10671721" "unprognostic (1.53e-1)" "unprognostic (2.23e-2)" "unprognostic (1.57e-1)" "unprognostic (3.49e-1)" "unprognostic (8.30e-2)" "unprognostic (9.68e-3)" "unprognostic (1.24e-2)" "unprognostic (3.19e-2)" "unprognostic (6.85e-3)" "unprognostic (3.70e-1)" "unprognostic (5.93e-2)" "unprognostic (5.48e-2)" "unprognostic (3.75e-2)" "unprognostic (1.65e-1)" "unprognostic (4.89e-2)" "unprognostic (2.57e-1)" "prognostic favorable (4.15e-5)" 39.2 48.6 67.6 37.8 72.0 66.0 55.7 87.7 87.8 46.5 63.6 38.9 31.2 42.6 48.0 36.9 47.0 36.6 39.8 66.0 67.8 48.0 44.0 43.5 57.8 66.2 68.0 65.1 35.7 50.1 41.7 43.3 66.8 42.1 36.9 83.7 42.6 36.5 59.0 38.2 40.3 32.7 68.5 48.1 37.6 75.2 67.3 69.0 51.5 56.5 53.0 43.9 38.0 85.4 56.4 45.3 83.7 70.1 53.8 51.6 75.9 42.9 72.4 68.6 88.4 73.0 63.2 74.2 48.0 44.0 84.9 37.5 71.9 48.6 86.8 41.7 48.1 61.9 49.6 61.5 62.9 45.2 60.8 43.6 74.8 56.1 78.1 65.8 56.7 59.5 62.3 117.6 56.4 72.3 70.3 78.6 51.2 28.2 31.3 75.4 68.5 72.7 53.7 58.7 72.7 56.0 62.1 53.4 69.6 54.3 104.9 75.8 37.3 25.0 50.2 35.1 62.0 90.0 79.6 81.6 40.7 66.7 46.9 93.8 38.2 76.4 59.6 41.0 76.3 71.5 72.1 72.6 43.7 61.9 78.5 73.8 73.2 79.5 45.5 29.8 84.9 68.8 67.6 72.0 87.7 87.8 66.0 67.8 66.2 68.0 66.8 68.5 67.3 85.4 132.9 60.9 88.3 129.3 272.2 227.5 241.1 102.6 206.1 139.8 146.1 87.9 89.0 65.8 121.9 84.6 148.0 99.0 246.9 149.6 99.7 76.5 249.9 246.6 134.0 123.1 107.7 82.7 106.4 55.9 74.3 143.2 115.2 267.8 142.8 119.0 68.2 47.0 56.2 134.6 96.4 103.3 118.0 70.3 622.0 102.4 133.9 162.8 188.5 112.4 160.7 95.7 178.2 168.9 221.6 70.5 176.3 91.4 261.6 246.5 87.9 72.6 154.6 199.0 52.6 129.7 139.9 379.3 279.6 195.6 237.7 161.7 285.2 107.0 102.0 304.1 GPIHBP1 "GPI-HBP1, LOC338328" ENSG00000277494 "Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1" Q8IV16 8 143213218-143217170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.7;breast: 54.5" "Cell type enriched" "Detected in some" 4 "Adipocytes: 356.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Karpas-707: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066302 Enhanced "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA066302: AB_2685654" "unprognostic (2.05e-1)" "unprognostic (3.11e-2)" "unprognostic (1.71e-3)" "unprognostic (2.43e-3)" "unprognostic (1.58e-1)" "unprognostic (9.50e-2)" "unprognostic (1.75e-3)" "unprognostic (8.01e-2)" "unprognostic (2.04e-1)" "unprognostic (1.30e-1)" "unprognostic (9.31e-2)" "unprognostic (8.69e-2)" "unprognostic (5.06e-3)" "unprognostic (9.65e-3)" "unprognostic (1.41e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-3)" 90.7 4.9 12.9 0.4 23.7 0.1 54.5 22.7 27.2 8.7 7.5 5.3 0.6 11.4 0.2 3.5 11.7 6.5 38.6 13.3 17.9 11.0 1.6 27.4 2.4 35.8 20.8 6.6 1.8 1.1 3.4 6.5 32.9 3.9 0.5 0.1 4.1 1.6 30.2 7.4 3.7 2.4 18.0 19.3 4.1 2.0 22.8 1.9 5.5 29.7 1.0 10.5 7.9 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 23.7 22.7 27.2 13.3 17.9 35.8 20.8 32.9 18.0 22.8 53.5 356.5 0.0 3.2 0.0 0.5 1.5 0.1 0.0 1.2 0.0 1.0 0.6 4.3 0.0 0.6 0.0 0.0 0.0 1.3 0.0 1.9 0.0 0.1 0.0 0.0 77.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 1.3 0.0 35.7 0.4 0.0 0.0 0.1 0.0 0.0 0.8 2.1 0.6 1.5 0.4 0.0 8.4 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 5.4 3.0 0.0 0.7 0.2 1.1 0.0 0.4 1.1 0.0 0.2 GPR132 G2A ENSG00000183484 "G protein-coupled receptor 132" Q9UNW8 14 105049395-105065445 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.0;lymphoid tissue: 7.8" "Cell type enhanced" "Detected in some" "B-cells: 23.6;Langerhans cells: 45.5;Macrophages: 30.2;monocytes: 19.1;NK-cells: 15.5;T-cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "HDLM-2: 26.9;Karpas-707: 26.6;THP-1: 8.2" "HPA029694, HPA029695" Supported NA NA "Cluster 34: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA029694: AB_10600213, HPA029695: AB_10601984" "unprognostic (2.71e-3)" "prognostic favorable (3.21e-4)" "unprognostic (1.68e-2)" "unprognostic (1.07e-3)" "unprognostic (1.16e-1)" "prognostic favorable (6.44e-4)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (3.35e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (4.18e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (6.71e-2)" "unprognostic (4.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.72e-1)" 2.1 0.7 0.9 7.0 0.7 8.0 0.9 0.7 0.9 0.9 1.0 1.3 1.0 0.6 0.4 0.8 1.6 1.4 0.8 0.8 1.0 5.4 0.5 2.7 7.7 1.6 1.1 0.3 0.7 0.3 0.5 1.5 1.2 0.8 0.9 0.3 0.9 0.3 0.5 2.6 4.3 0.8 1.0 7.8 1.7 0.3 1.2 1.9 4.6 0.6 4.5 2.4 1.1 1.3 0.0 0.1 0.1 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.5 3.5 0.6 0.0 0.0 0.7 0.0 0.0 0.0 26.9 0.3 0.6 0.1 0.0 0.1 2.1 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 26.6 0.0 0.8 0.0 2.7 0.1 0.0 0.0 2.1 0.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 8.2 0.4 0.1 0.1 0.0 0.3 0.7 2.6 0.3 0.0 2.4 0.0 9.6 6.0 5.5 6.1 7.7 5.9 4.2 4.8 5.5 5.7 4.5 4.8 5.3 4.7 5.8 9.1 3.1 3.6 5.0 0.9 0.7 0.7 0.9 0.8 1.0 1.6 1.1 1.2 1.0 1.2 1.3 0.6 0.0 1.9 0.7 23.6 1.7 0.1 1.0 0.0 0.0 0.3 0.3 0.8 0.0 0.7 1.8 0.0 0.1 12.2 0.0 1.9 0.4 0.0 2.2 0.8 0.9 0.0 4.0 0.7 0.6 0.3 0.4 1.1 5.2 12.7 0.0 0.0 0.0 3.9 0.0 0.6 0.0 0.0 7.1 45.5 0.2 0.0 30.2 5.4 7.5 19.1 0.0 15.5 0.0 0.1 1.2 0.0 0.0 11.7 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 1.6 0.0 20.7 0.0 0.0 0.9 GPR55 ENSG00000135898 "G protein-coupled receptor 55" Q9Y2T6 2 230907318-230961066 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;lymphoid tissue: 4.4;testis: 4.7" "Cell type enhanced" "Detected in some" "B-cells: 2.1;Enteroendocrine cells: 1.8;Excitatory neurons: 2.3;Langerhans cells: 3.1;Plasma cells: 2.4;T-cells: 4.2" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 4 "basal ganglia: 4.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "Karpas-707: 32.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (9.88e-4)" "unprognostic (2.60e-2)" "unprognostic (2.27e-1)" "unprognostic (4.24e-3)" "unprognostic (5.93e-2)" "unprognostic (1.12e-4)" "unprognostic (3.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "unprognostic (4.37e-2)" "unprognostic (3.18e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (2.42e-2)" "unprognostic (4.26e-1)" 0.2 0.0 0.3 1.8 4.6 0.2 0.5 0.0 0.5 0.1 0.0 0.8 1.3 0.1 0.0 0.5 0.1 0.5 0.1 0.3 0.4 0.0 0.2 0.5 2.9 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 1.0 0.2 0.0 0.4 2.2 0.1 0.0 4.1 0.7 4.7 1.0 1.9 0.1 0.0 4.4 0.9 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 2.1 0.0 0.6 0.0 0.0 0.0 0.0 6.5 0.0 0.2 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.8 32.0 0.0 0.0 0.2 0.9 0.7 0.0 1.0 0.1 0.0 3.1 0.0 0.0 1.2 0.0 0.0 0.0 6.0 0.0 0.0 2.3 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.3 0.1 1.9 0.1 0.9 0.2 0.9 0.1 0.7 1.3 1.7 0.3 4.6 0.0 0.5 0.3 0.4 0.1 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.3 2.1 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.8 0.0 0.0 0.1 1.8 0.0 2.3 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.4 0.0 0.1 0.0 0.1 1.4 0.0 0.3 3.1 0.9 0.0 1.2 0.0 1.0 0.9 0.0 1.0 0.5 0.1 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.2 0.1 0.2 0.1 GPR63 "PSP24(beta), PSP24B" ENSG00000112218 "G protein-coupled receptor 63" Q9BZJ6 6 96794125-96837477 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Early spermatids: 31.4;Excitatory neurons: 46.2;Granulosa cells: 31.2;Inhibitory neurons: 20.3;Late spermatids: 35.2;Spermatocytes: 24.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 8.8;HHSteC: 13.5;Karpas-707: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039103 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane, Cytosol" "HPA039103: AB_10672841" "unprognostic (8.22e-2)" "unprognostic (2.77e-1)" "unprognostic (1.71e-2)" "unprognostic (1.02e-2)" "unprognostic (1.83e-1)" "unprognostic (1.33e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (3.39e-1)" "unprognostic (2.53e-2)" "unprognostic (7.29e-3)" "unprognostic (3.00e-1)" "unprognostic (2.03e-3)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-2)" 0.5 0.9 1.4 0.7 3.5 0.1 0.4 0.7 2.7 1.5 2.7 1.2 1.5 0.5 0.3 0.5 0.7 0.7 0.5 1.5 0.1 0.3 0.0 0.3 0.1 1.6 0.6 1.0 1.4 1.0 0.9 0.7 2.0 0.9 1.8 0.2 0.4 0.5 0.2 0.4 1.1 0.6 0.0 0.3 1.1 2.4 0.9 0.6 0.6 0.1 0.2 0.8 1.4 1.8 0.0 0.1 1.6 0.4 2.3 0.8 0.4 1.0 0.0 0.0 0.2 0.2 1.2 0.1 0.0 0.1 1.3 1.2 5.4 2.5 0.0 8.8 4.1 5.2 0.4 0.0 13.5 3.3 0.6 2.5 0.4 0.0 3.7 0.3 0.0 7.6 3.8 20.8 0.5 0.4 2.5 0.0 5.4 0.0 0.7 0.0 1.9 4.3 0.3 0.2 2.4 1.5 0.3 3.3 0.6 1.7 1.3 0.7 0.0 1.4 2.1 0.2 2.0 1.6 0.9 0.1 0.8 2.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.0 1.4 3.5 0.7 2.7 1.5 0.1 1.6 0.6 2.0 0.0 0.9 1.8 0.6 0.0 0.0 2.3 0.2 1.9 0.7 0.3 4.0 1.5 0.6 0.9 0.7 2.8 0.1 1.8 0.0 0.2 0.3 0.1 0.0 0.4 31.4 0.1 0.5 0.7 3.0 0.4 46.2 0.9 0.7 2.5 1.1 0.1 0.0 31.2 1.1 0.0 0.2 0.0 20.3 0.5 0.0 0.0 8.9 35.2 3.4 0.4 1.8 9.4 0.1 0.2 0.0 11.6 4.8 0.4 0.1 4.9 1.0 1.1 0.1 0.2 0.0 0.2 0.0 0.4 2.2 24.6 10.5 1.9 0.3 0.1 0.4 2.1 0.5 0.3 GPRC5D ENSG00000111291 "G protein-coupled receptor class C group 5 member D" Q9NZD1 12 12940775-12952147 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "skin 1: 47.8" "Cell type enhanced" "Detected in some" "Early spermatids: 6.8;Gastric mucus-secreting cells: 5.6;Late spermatids: 6.2;Melanocytes: 5.4;Plasma cells: 16.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "memory B-cell: 21.9;naive B-cell: 7.5" "Lineage enriched" "Detected in many" 14 "B-cells: 21.9" "Group enriched" "Detected in many" 9 "Karpas-707: 84.5;RPMI-8226: 85.9;U-266/84: 25.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA071909 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 61: Skin - Cornification" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA071909: AB_2686470" "unprognostic (4.27e-2)" "unprognostic (8.58e-2)" "unprognostic (4.68e-2)" "unprognostic (2.02e-1)" "unprognostic (4.34e-2)" "prognostic favorable (5.09e-4)" "unprognostic (3.00e-5)" "unprognostic (4.06e-2)" "unprognostic (3.06e-2)" "unprognostic (5.53e-2)" "unprognostic (7.01e-2)" "unprognostic (2.27e-2)" "unprognostic (8.33e-3)" "unprognostic (9.54e-2)" "unprognostic (1.83e-1)" "unprognostic (1.11e-2)" "unprognostic (6.63e-2)" 0.9 0.6 0.2 0.4 0.4 0.6 3.0 0.1 0.2 1.2 2.0 2.7 1.8 0.2 0.0 2.5 0.3 0.8 0.8 0.2 0.4 0.6 1.0 7.2 0.7 1.1 1.2 0.5 2.1 0.0 1.5 0.3 0.5 1.2 2.3 0.3 4.5 0.0 0.2 47.8 2.7 0.0 0.3 1.6 2.3 2.7 0.6 0.1 1.2 0.0 1.1 0.7 1.0 0.3 1.3 1.4 0.0 1.5 0.0 0.0 3.3 0.4 0.0 0.0 0.3 1.3 3.2 0.1 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 7.6 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 4.1 84.5 0.2 3.1 0.0 0.0 0.8 3.9 0.1 0.1 0.0 85.9 0.0 3.4 2.6 0.5 1.9 1.4 0.0 3.5 0.0 0.0 2.3 0.0 3.9 0.1 0.0 4.4 25.2 1.1 0.0 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 21.9 0.2 0.0 0.1 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.2 0.4 0.1 0.2 0.2 0.4 1.1 1.2 0.5 0.3 0.6 0.3 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.1 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 5.6 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.3 0.0 6.2 0.0 0.1 5.4 1.9 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 GPRIN3 "FLJ42625, GRIN3" ENSG00000185477 "GPRIN family member 3" Q6ZVF9 4 89236383-89307800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 78.7;Macrophages: 53.9;Sertoli cells: 78.9;T-cells: 76.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Karpas-707: 102.6;RPMI-8226: 27.7;SCLC-21H: 27.2;U-266/70: 15.9;U-266/84: 13.2" "Region enhanced" "Detected in many" "basal ganglia: 16.2" "HPA043148, HPA057666, HPA059092" Enhanced Approved Nucleoplasm,Nucleoli No NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoli Nucleoplasm "HPA043148: AB_2678341, HPA057666: AB_2683496, HPA059092: AB_2683902" "unprognostic (9.05e-2)" "unprognostic (4.92e-2)" "prognostic favorable (7.22e-5)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (1.07e-3)" "unprognostic (3.36e-1)" "unprognostic (1.98e-1)" "unprognostic (1.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.34e-3)" "unprognostic (3.13e-1)" "prognostic favorable (8.33e-4)" "unprognostic (1.91e-1)" "unprognostic (5.35e-2)" "unprognostic (3.93e-1)" "unprognostic (7.82e-4)" 2.7 1.2 4.1 9.0 9.5 7.8 1.4 17.8 3.1 2.2 0.9 5.3 6.2 1.4 0.7 0.9 0.9 3.5 4.0 2.2 7.3 3.9 2.0 6.9 10.2 4.3 6.5 3.2 5.1 0.6 2.9 1.0 4.5 0.8 7.1 3.5 1.5 0.6 1.0 0.6 5.3 1.4 4.1 7.1 3.6 0.4 5.0 2.8 1.3 3.2 7.9 2.7 1.0 5.9 0.0 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.8 0.1 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 102.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.7 0.0 27.7 0.3 0.1 27.2 0.6 0.0 0.1 1.1 1.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 15.9 13.2 0.1 0.5 0.0 0.0 0.0 0.3 0.0 2.8 1.0 3.8 0.2 2.7 2.2 0.9 0.0 1.1 1.1 0.0 1.9 1.5 0.0 3.4 1.0 4.1 9.5 17.8 3.1 2.2 7.3 4.3 6.5 4.5 4.1 5.0 5.9 11.1 0.0 22.6 10.1 6.7 1.1 0.9 0.1 0.0 12.2 1.6 1.7 20.3 8.6 5.0 3.7 0.0 0.2 51.2 17.4 1.9 2.0 0.2 5.8 3.4 11.7 78.7 6.5 21.7 9.4 0.1 3.0 15.8 15.0 7.6 12.2 1.8 0.4 18.7 26.9 32.7 38.0 0.0 28.2 29.0 0.0 0.3 53.9 1.8 41.2 7.4 1.0 23.7 26.2 0.5 1.3 11.0 1.2 48.6 0.3 16.3 1.9 0.7 10.8 78.9 3.3 32.7 0.1 0.8 0.3 1.0 0.3 76.9 0.7 26.2 0.5 GRK6 GPRK6 ENSG00000198055 "G protein-coupled receptor kinase 6" P43250 5 177403204-177442901 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 134.1" "Cell type enhanced" "Detected in many" "Late spermatids: 90.6;NK-cells: 123.6;Plasma cells: 112.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015327, HPA018903" Approved Approved Mitochondria NA NA 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Mitochondria "HPA015327: AB_1850334, HPA018903: AB_1850335" "unprognostic (1.06e-1)" "unprognostic (3.39e-2)" "unprognostic (4.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.66e-6)" "unprognostic (2.63e-1)" "unprognostic (6.45e-2)" "unprognostic (8.96e-2)" "prognostic favorable (1.22e-4)" "unprognostic (1.74e-2)" "unprognostic (1.99e-2)" "unprognostic (1.83e-3)" "unprognostic (1.15e-1)" "unprognostic (4.00e-2)" "unprognostic (3.47e-1)" 14.0 10.8 12.6 36.7 12.3 134.1 12.7 8.1 16.0 11.3 9.2 19.7 18.5 14.8 2.4 21.5 13.3 12.4 13.3 12.7 9.6 11.0 13.6 21.8 61.6 13.3 10.5 11.1 13.3 5.5 10.5 6.8 11.1 15.8 8.8 2.2 17.9 7.4 15.7 15.5 29.1 9.2 8.9 63.3 15.9 22.3 10.7 35.9 10.2 6.2 30.2 16.6 13.2 13.9 41.1 44.2 15.7 67.8 4.6 7.4 66.4 29.4 15.1 36.2 35.5 103.0 34.1 48.7 44.0 15.6 53.5 29.1 24.3 67.0 14.3 133.9 77.3 43.5 36.2 36.0 24.1 58.6 52.8 11.7 16.1 36.2 21.4 8.8 20.5 87.8 45.6 170.9 11.2 117.4 61.3 61.4 26.7 20.4 48.1 57.1 25.5 71.2 10.7 32.9 36.0 48.6 24.3 42.5 56.8 7.1 32.6 63.4 26.3 29.6 43.8 31.2 75.1 48.8 64.2 40.7 20.0 95.0 29.2 12.7 20.9 74.5 23.6 36.5 17.0 19.3 19.6 21.9 11.9 19.5 20.3 18.0 50.6 40.3 51.9 12.5 26.4 22.6 12.6 12.3 8.1 16.0 12.7 9.6 13.3 10.5 11.1 8.9 10.7 13.9 9.2 0.0 2.2 2.6 71.7 23.7 60.3 4.9 5.7 10.5 14.7 17.3 3.0 10.0 4.6 3.7 6.2 13.9 70.8 18.2 15.6 6.0 37.2 7.4 8.2 6.6 11.4 41.7 3.7 8.3 12.6 9.7 16.8 6.4 14.7 13.9 10.0 6.5 20.4 16.8 3.5 14.3 4.1 29.8 18.8 90.6 6.2 41.2 14.2 2.8 26.4 9.0 123.6 2.0 3.3 10.3 14.0 5.3 112.2 61.1 11.8 8.5 2.0 8.6 13.1 8.4 10.7 3.9 4.2 11.9 20.3 12.7 66.5 12.1 17.1 56.6 GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 213.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" NA NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA036322: AB_10670796, HPA036323: AB_2675059" "unprognostic (1.54e-2)" "unprognostic (6.49e-2)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (7.00e-3)" "unprognostic (1.91e-1)" "unprognostic (3.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.98e-1)" "unprognostic (5.06e-1)" "unprognostic (1.45e-1)" 28.4 18.2 11.0 22.3 12.3 84.2 80.9 12.0 16.1 26.7 14.3 38.2 36.1 26.2 41.8 16.4 24.6 27.6 19.6 10.7 11.5 25.1 104.0 35.7 25.6 13.2 12.2 19.9 33.6 30.3 12.6 48.2 13.2 20.2 41.9 9.7 32.9 21.2 10.9 18.8 29.8 19.1 11.9 34.0 38.1 19.5 13.0 22.7 27.7 14.4 24.0 27.3 15.4 13.5 67.0 26.5 25.2 56.3 80.9 49.1 35.3 21.3 56.8 45.0 42.1 37.0 67.8 30.9 32.3 26.8 24.1 27.5 16.5 25.1 26.8 27.3 34.1 41.5 40.9 27.3 39.7 89.6 67.1 33.4 26.7 26.3 33.3 54.5 39.3 18.0 63.2 213.5 30.5 50.3 34.2 92.0 17.9 103.0 21.0 34.4 55.9 172.4 29.4 42.8 36.2 32.7 55.6 129.1 72.3 29.9 71.1 88.8 28.5 55.3 49.3 21.8 53.6 119.6 151.9 50.0 41.0 116.3 68.3 26.0 80.1 65.7 32.0 103.0 28.4 27.7 24.7 28.4 80.5 22.6 16.8 19.5 13.2 46.6 93.5 34.2 34.5 51.4 11.0 12.3 12.0 16.1 10.7 11.5 13.2 12.2 13.2 11.9 13.0 13.5 53.1 51.3 58.7 10.1 33.0 18.0 32.0 51.9 29.0 12.2 26.1 19.9 12.2 48.6 48.9 29.5 8.4 81.9 32.6 52.2 5.9 41.1 59.1 28.9 26.5 39.7 43.0 47.1 12.3 30.3 61.2 49.5 49.5 49.4 36.8 38.3 37.9 72.7 126.4 16.8 10.6 51.6 30.5 88.1 33.2 46.7 43.2 78.0 39.2 14.0 44.8 28.0 20.6 8.5 14.2 29.4 49.5 28.6 87.5 25.3 50.6 26.8 43.2 20.1 26.3 27.1 26.0 49.6 31.0 16.0 14.8 66.9 32.2 24.4 44.3 29.6 HECA "dJ225E12.1, HDC, HDCL, hHDC" ENSG00000112406 "Hdc homolog, cell cycle regulator" Q9UBI9 6 139135080-139180802 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 125.8;Langerhans cells: 153.3;Suprabasal keratinocytes: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012581, HPA042313" Uncertain Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA012581: , HPA042313: AB_10796903" "unprognostic (2.98e-2)" "unprognostic (2.39e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-1)" "unprognostic (7.31e-2)" "unprognostic (3.38e-3)" "unprognostic (4.29e-2)" "unprognostic (3.27e-1)" "unprognostic (7.39e-2)" "unprognostic (2.00e-2)" "unprognostic (5.77e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (8.09e-4)" "unprognostic (3.47e-1)" "unprognostic (2.59e-1)" "unprognostic (4.72e-3)" "unprognostic (5.77e-2)" 17.2 8.7 10.5 21.5 10.4 39.2 14.2 10.1 13.8 13.8 7.8 12.7 16.5 13.4 6.4 19.3 12.6 13.1 17.4 12.1 11.3 6.4 10.8 19.2 28.8 10.7 11.1 16.7 9.9 9.7 7.0 10.9 12.6 9.5 12.4 3.9 17.9 8.1 20.3 26.1 17.6 13.8 11.9 27.5 12.0 9.5 12.4 31.6 9.6 15.8 25.8 14.2 15.9 14.1 4.8 1.0 9.2 10.5 20.8 19.0 6.8 8.6 14.4 3.8 8.8 1.9 5.3 20.9 12.2 17.9 9.1 7.9 5.6 7.8 7.0 32.9 11.9 10.5 4.6 0.3 6.5 18.6 9.2 21.7 18.8 8.3 10.1 10.4 12.9 13.8 4.5 27.5 7.1 4.9 9.0 15.1 1.7 4.2 1.7 14.0 9.3 10.6 3.3 15.2 8.8 2.6 7.1 19.1 5.5 10.2 4.4 24.4 16.4 6.7 6.3 15.2 7.5 16.4 13.1 18.8 2.4 10.7 3.8 7.0 1.3 2.0 2.8 1.8 3.5 1.5 4.3 3.8 1.0 1.9 4.1 4.1 5.0 1.5 5.5 1.1 3.9 1.4 10.5 10.4 10.1 13.8 12.1 11.3 10.7 11.1 12.6 11.9 12.4 14.1 35.6 6.4 13.9 10.1 38.2 125.8 22.4 15.9 38.7 1.8 29.1 14.4 41.9 8.6 11.6 11.0 2.1 7.3 70.2 53.4 0.0 7.0 12.0 37.8 18.5 34.9 13.1 22.5 20.4 9.8 6.2 22.3 11.7 53.4 13.3 11.7 36.8 13.0 19.1 1.7 23.2 25.5 16.2 84.3 153.3 12.4 15.5 65.7 44.4 38.4 25.7 6.6 29.9 13.0 10.9 14.7 28.4 19.5 48.8 42.4 34.8 4.7 12.3 2.7 52.6 26.4 23.7 12.6 6.7 33.7 142.2 17.4 76.7 10.8 17.2 59.1 HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699010-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 311.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 23.8;Fibroblasts: 95.8;Hepatic stellate cells: 25.0;Muller glia cells: 36.2;Smooth muscle cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 94.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.0" "Cell line enhanced" "Detected in some" "ASC TERT1: 171.6;HHSteC: 135.8;HL-60: 82.4;hTEC/SVTERT24-B: 87.4;Karpas-707: 240.7;U-87 MG: 62.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved "Secreted to blood" NA NA 4110000 14000 "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 2: Karpas-707 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "CAB010333: AB_647965, HPA040360: AB_2676939, HPA044088: AB_2678804" "unprognostic (5.24e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (7.45e-5)" "unprognostic (1.66e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-1)" "unprognostic (5.29e-2)" "prognostic unfavorable (5.59e-4)" "unprognostic (7.90e-3)" "unprognostic (2.92e-2)" "unprognostic (1.14e-2)" "unprognostic (2.06e-2)" 7.9 19.8 1.6 6.3 3.3 12.3 5.2 1.5 7.8 7.2 1.8 4.4 2.6 8.1 3.6 2.9 5.4 16.6 4.7 2.9 3.6 11.8 30.3 19.5 2.2 3.6 2.3 1.8 2.1 2.1 2.4 311.9 4.3 7.2 3.4 14.2 2.4 6.4 0.8 0.9 2.3 7.1 1.8 6.5 3.9 2.4 2.9 1.5 5.6 3.9 1.5 10.4 6.3 3.3 0.0 0.0 0.1 0.0 21.6 171.6 0.1 0.7 33.4 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.1 6.0 0.0 0.0 135.8 82.4 0.4 41.4 0.0 87.4 0.3 0.0 2.2 0.0 0.1 240.7 0.6 0.0 0.0 56.4 0.0 0.0 0.2 0.8 0.0 7.5 0.0 0.0 0.2 9.3 0.0 0.1 0.0 0.2 0.0 3.5 0.4 2.0 0.0 0.1 0.0 0.1 0.0 0.0 62.6 16.9 0.1 94.0 15.2 3.9 0.0 18.7 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 3.2 0.0 17.3 1.0 0.0 4.3 1.6 3.3 1.5 7.8 2.9 3.6 3.6 2.3 4.3 1.8 2.9 3.3 6.2 0.0 4.1 16.3 0.0 1.0 0.2 0.0 1.8 0.2 0.3 0.5 1.3 1.5 0.6 0.0 0.0 5.6 0.0 0.0 0.0 0.0 15.2 1.0 23.8 6.2 0.0 2.1 0.3 0.0 4.9 95.8 0.5 0.9 1.3 0.0 25.0 0.5 18.4 0.0 22.4 0.0 0.0 12.5 1.9 2.3 18.3 14.0 1.8 7.5 10.5 36.2 1.0 0.0 0.1 0.0 0.0 10.9 0.3 0.4 0.0 0.0 0.0 0.7 13.1 0.9 26.2 0.2 0.3 0.3 0.1 12.0 0.6 1.3 0.0 0.4 HHLA2 "B7-H5, B7-H7, B7H7, B7y" ENSG00000114455 "HERV-H LTR-associating 2" Q9UM44 3 108296490-108378285 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 129.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 274.7;Paneth cells: 64.2;Proximal enterocytes: 186.8" "Group enriched" "Detected in many" 12 "colorectal cancer: 9.2;lung cancer: 5.0;pancreatic cancer: 5.1;renal cancer: 16.6;stomach cancer: 6.2" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 1.7;HDLM-2: 4.0;Karpas-707: 2.8" "Low region specificity" "Detected in all" HPA055478 Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055478: AB_2682830" "unprognostic (1.12e-2)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (3.11e-1)" "unprognostic (2.30e-1)" "unprognostic (1.59e-2)" "unprognostic (8.14e-5)" "unprognostic (1.76e-1)" "unprognostic (2.28e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-3)" "unprognostic (1.24e-1)" "unprognostic (1.62e-3)" "unprognostic (1.47e-1)" "unprognostic (2.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.66e-2)" 0.4 0.2 0.5 5.6 0.4 1.1 0.2 0.7 1.3 0.0 0.0 87.9 86.8 0.3 0.8 0.5 3.7 29.2 0.2 0.6 0.7 7.6 0.1 5.7 0.6 0.7 0.3 0.1 2.9 0.1 0.2 0.1 0.6 0.2 83.0 1.2 0.2 0.3 0.5 0.3 129.9 2.0 0.2 0.3 9.4 3.3 0.6 0.4 0.2 0.0 0.3 0.0 0.0 0.8 0.2 0.3 0.2 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.2 1.7 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.0 0.0 4.0 0.1 0.1 1.4 0.2 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 2.8 0.0 0.2 0.4 1.5 0.5 0.2 0.3 0.3 0.1 0.8 0.0 0.1 0.7 0.7 0.7 0.0 0.1 0.5 0.1 0.2 0.1 0.1 0.7 0.2 0.2 1.3 0.7 0.3 0.0 0.4 0.1 0.5 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.1 1.8 0.1 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.2 0.5 0.4 0.7 1.3 0.6 0.7 0.7 0.3 0.6 0.2 0.6 0.8 0.0 0.0 2.0 0.7 0.4 0.0 0.1 0.7 0.0 0.0 0.7 0.3 0.2 27.1 1.6 0.0 0.0 0.0 0.0 274.7 0.0 8.5 3.3 3.2 0.0 0.3 1.8 0.0 1.3 37.6 0.1 0.3 2.6 0.1 2.5 0.0 0.0 0.0 0.1 0.0 0.5 12.5 2.0 0.0 0.7 4.2 0.3 0.3 0.0 0.0 1.1 0.0 0.0 0.5 0.9 35.7 64.2 0.0 0.0 0.1 186.8 20.4 19.4 0.0 0.0 0.1 0.1 0.7 0.3 0.0 0.0 0.1 0.5 0.0 17.7 0.1 HIGD1C Gm921 ENSG00000214511 "HIG1 hypoxia inducible domain family member 1C" A8MV81 12 50953922-50970506 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.9" "Cell type enhanced" "Detected in some" "Astrocytes: 6.2;Early spermatids: 8.2;Excitatory neurons: 3.3;Inhibitory neurons: 4.0;Oligodendrocyte precursor cells: 7.1;Oligodendrocytes: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.2;Karpas-707: 1.6" "Region enriched" "Detected in single" 10 "hypothalamus: 1.0" "Low region specificity" "Detected in all" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.81e-1)" "unprognostic (3.10e-1)" "unprognostic (1.01e-1)" "unprognostic (4.21e-1)" "unprognostic (2.70e-1)" "unprognostic (5.49e-1)" "unprognostic (2.99e-1)" 0.4 0.3 0.3 0.0 1.1 0.0 0.1 2.9 1.2 0.3 0.6 0.2 0.0 0.2 0.0 0.1 0.5 0.5 0.0 0.4 0.4 0.2 1.1 0.6 0.7 0.9 0.8 0.4 1.0 0.5 0.1 0.0 1.0 0.1 0.3 0.2 0.4 0.2 0.3 0.6 0.3 0.3 0.3 0.3 0.5 1.7 0.7 0.4 1.0 0.2 0.3 0.3 0.0 2.1 0.0 0.0 0.1 0.5 0.0 0.5 1.2 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.1 2.9 1.2 0.4 0.4 0.9 0.8 1.0 0.3 0.7 2.1 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 1.9 0.0 0.0 0.0 7.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 HIGD2A "MGC2198, RCF1B" ENSG00000146066 "HIG1 hypoxia inducible domain family member 2A" Q9BW72 5 176388751-176389761 "Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042715 Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 32: Non-specific - Translation" Mitochondria Cytosol "HPA042715: AB_2678127" "unprognostic (9.24e-2)" "unprognostic (6.31e-3)" "unprognostic (7.96e-2)" "unprognostic (3.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.94e-2)" "prognostic unfavorable (9.47e-4)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (1.98e-2)" "unprognostic (3.11e-3)" "unprognostic (9.56e-2)" "unprognostic (2.39e-2)" "unprognostic (1.45e-1)" "unprognostic (8.09e-2)" "unprognostic (1.78e-1)" "unprognostic (9.65e-2)" 146.1 175.6 143.3 87.0 146.2 133.1 113.5 147.2 175.0 104.7 168.0 199.4 118.9 111.7 51.3 130.0 105.0 80.5 318.7 139.8 146.0 182.7 163.3 95.7 132.9 143.9 142.2 118.7 108.7 204.9 125.1 54.6 141.6 127.9 96.3 45.5 163.2 92.7 422.5 140.8 136.6 68.1 145.3 129.3 148.6 66.0 149.0 110.7 114.0 297.9 92.7 152.3 105.2 145.7 104.9 166.6 99.0 172.6 98.5 186.4 262.2 66.6 109.7 164.7 206.4 176.0 202.2 183.3 149.9 107.1 214.2 127.3 146.2 260.6 65.9 424.0 234.0 92.6 161.7 244.7 137.4 149.7 230.1 238.2 213.2 93.7 113.3 126.3 141.7 146.5 104.0 341.5 124.0 315.9 165.3 178.1 124.8 195.5 181.7 157.1 75.6 324.7 265.5 158.7 107.9 141.5 71.4 295.2 310.5 100.7 173.3 233.7 96.8 118.5 124.7 110.2 142.5 165.2 216.6 158.4 150.5 254.1 77.5 284.2 743.6 219.8 391.2 975.8 389.5 618.1 540.1 452.6 930.0 496.0 488.1 464.2 124.6 308.0 1024.9 616.8 621.8 971.3 143.3 146.2 147.2 175.0 139.8 146.0 143.9 142.2 141.6 145.3 149.0 145.7 100.4 73.7 78.6 0.0 212.5 232.2 332.8 358.0 272.0 60.5 225.5 288.5 145.3 174.5 191.0 182.1 12.5 223.0 184.2 415.6 534.1 204.5 83.9 140.0 120.6 110.9 266.6 90.8 0.0 237.3 185.4 129.1 142.2 124.2 130.0 157.0 120.3 217.0 378.7 65.6 0.0 450.7 219.7 458.8 345.2 56.8 140.1 292.1 257.9 0.0 449.7 138.1 230.7 0.0 0.0 110.0 493.0 85.0 184.2 292.6 313.8 542.8 142.3 47.7 118.3 145.9 138.8 96.7 79.4 301.8 225.0 280.2 223.7 182.1 385.3 532.4 HIVEP3 "FLJ16752, KBP-1, KBP1, KIAA1555, KRC, Schnurri-3, SHN3, ZAS3, ZNF40C" ENSG00000127124 "HIVEP zinc finger 3" Q5T1R4 1 41506365-42035925 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.6" "Group enriched" "Detected in many" 5 "Astrocytes: 83.9;Excitatory neurons: 219.6;Inhibitory neurons: 271.9;Microglial cells: 163.9;Oligodendrocyte precursor cells: 83.9;Oligodendrocytes: 196.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HDLM-2: 18.8;hTEC/SVTERT24-B: 9.5;Karpas-707: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005728 Approved Supported Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA005728: AB_10612117" "unprognostic (2.87e-3)" "unprognostic (2.38e-2)" "unprognostic (4.65e-2)" "unprognostic (2.56e-1)" "unprognostic (1.55e-2)" "unprognostic (6.50e-2)" "unprognostic (2.70e-3)" "unprognostic (3.73e-1)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "unprognostic (2.07e-8)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" 1.6 0.6 0.8 2.1 2.1 1.6 1.4 1.4 1.6 0.4 0.0 0.5 0.4 0.4 0.3 1.9 0.5 0.7 0.8 2.0 0.0 1.0 0.3 1.9 1.7 0.7 0.4 0.5 0.8 0.4 2.1 0.6 1.0 1.4 0.5 0.6 1.6 0.3 0.6 4.6 0.6 0.8 0.1 1.1 0.7 0.3 0.5 6.6 1.5 0.4 2.1 1.8 0.5 0.3 1.9 0.6 0.2 1.8 2.2 1.0 0.0 0.9 0.2 2.3 4.0 0.1 0.3 4.0 0.6 1.0 1.5 2.7 0.4 0.4 3.1 18.8 0.5 0.2 0.9 0.0 0.4 0.3 0.3 5.6 0.4 9.5 1.1 0.6 0.5 1.3 0.0 11.0 1.8 1.2 3.0 0.8 0.6 0.6 2.3 2.0 2.9 2.2 1.5 0.4 2.0 0.6 2.6 0.7 0.5 1.1 0.9 3.4 3.4 2.0 2.2 0.6 4.6 3.3 1.4 2.6 8.1 0.2 7.5 0.0 0.5 0.0 0.6 1.1 0.1 0.1 0.2 0.3 0.4 0.4 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.4 0.8 2.1 1.4 1.6 2.0 0.0 0.7 0.4 1.0 0.1 0.5 0.3 5.9 6.4 10.5 83.9 9.6 23.7 26.5 4.3 17.6 16.4 15.1 11.0 6.9 5.7 8.2 1.8 2.1 0.4 17.6 3.5 1.9 3.1 9.9 1.2 7.7 7.5 3.6 4.4 219.6 2.7 4.4 11.1 1.5 2.8 1.3 0.2 11.4 2.5 6.2 25.2 271.9 1.2 2.0 6.5 17.3 31.9 8.7 15.0 5.4 163.9 9.1 16.0 27.8 83.9 196.0 3.1 0.1 4.1 3.3 15.5 1.9 3.2 1.1 3.5 6.6 23.9 7.4 11.3 8.6 23.7 8.7 0.8 14.5 10.0 0.9 11.1 HLCS HCS ENSG00000159267 "Holocarboxylase synthetase" P50747 21 36748626-36990236 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 86.2;Inhibitory neurons: 99.7;Oligodendrocyte precursor cells: 79.9;Oligodendrocytes: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017379 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA017379: AB_1850768" "prognostic unfavorable (7.72e-4)" "unprognostic (2.41e-1)" "unprognostic (3.93e-2)" "unprognostic (2.05e-1)" "unprognostic (2.75e-1)" "unprognostic (1.44e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-1)" "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-1)" "unprognostic (7.44e-2)" "unprognostic (2.43e-1)" "unprognostic (2.55e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-3)" "unprognostic (3.02e-1)" 5.0 5.1 4.9 4.2 5.5 3.3 7.4 9.1 5.8 5.1 9.4 4.7 4.2 4.0 7.0 6.1 5.3 4.2 3.7 6.3 5.4 6.4 10.6 4.9 3.7 5.9 4.6 3.8 7.6 10.6 8.8 4.1 6.3 8.9 4.4 6.1 8.5 6.6 13.3 2.8 4.9 4.5 4.1 3.1 5.7 5.7 5.4 3.3 10.7 6.2 4.3 5.4 2.8 5.5 23.8 10.4 13.0 9.6 14.8 13.7 13.3 13.0 12.7 7.1 7.0 10.8 11.0 10.6 6.4 21.4 13.0 8.2 5.9 11.6 5.5 21.0 9.2 16.4 9.6 6.7 14.9 8.6 11.0 10.2 17.0 10.6 23.6 15.5 9.0 12.0 19.7 31.9 17.4 14.2 4.6 5.4 21.8 16.7 11.3 7.1 7.5 11.2 10.8 24.8 8.3 9.9 16.7 8.8 14.8 10.0 16.2 9.1 10.5 9.1 2.7 8.9 7.8 25.6 19.8 7.1 14.6 11.1 10.7 1.9 0.8 0.8 3.6 2.0 2.9 1.2 1.9 2.3 0.8 1.3 2.4 2.2 1.2 4.8 5.1 1.9 1.6 1.8 4.9 5.5 9.1 5.8 6.3 5.4 5.9 4.6 6.3 4.1 5.4 5.5 3.0 9.6 12.5 46.4 4.1 3.3 9.2 5.3 6.8 12.8 9.4 7.4 4.5 8.6 8.4 12.9 22.9 8.9 5.1 3.5 7.9 7.8 5.6 8.0 8.0 3.8 6.0 7.4 86.2 8.1 5.4 5.1 9.7 8.0 5.7 7.9 4.2 18.5 4.6 18.5 99.7 5.2 4.1 5.1 2.1 4.3 4.4 4.0 0.0 45.9 3.2 5.6 8.2 79.9 80.1 9.0 2.9 7.2 4.2 7.8 8.0 6.1 9.2 14.2 0.0 9.0 6.8 5.2 11.5 8.7 4.0 5.1 5.5 11.1 5.4 6.9 HMGN5 NSBP1 ENSG00000198157 "High mobility group nucleosome binding domain 5" P82970 X 81113699-81201913 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 107.4" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 113.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 209.6;Karpas-707: 298.5" "Low region specificity" "Detected in all" "HPA000511, HPA076238" Approved Supported Nucleoplasm,Mitochondria NA NA 41000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Mitochondria "HPA000511: AB_1079505, HPA076238: " "unprognostic (1.49e-2)" "unprognostic (1.44e-1)" "unprognostic (3.72e-2)" "unprognostic (1.55e-1)" "unprognostic (1.07e-1)" "unprognostic (3.98e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "unprognostic (9.63e-3)" "prognostic favorable (6.60e-4)" "unprognostic (2.78e-3)" "unprognostic (1.16e-1)" "unprognostic (2.32e-3)" "unprognostic (3.06e-2)" "unprognostic (1.07e-1)" "unprognostic (6.53e-2)" "unprognostic (1.08e-1)" 13.2 24.6 31.6 6.1 31.8 34.0 14.5 28.8 60.6 12.7 27.7 16.6 23.0 17.2 65.2 14.8 17.5 11.0 10.2 29.3 32.3 27.6 23.0 8.7 5.3 35.3 32.5 20.4 12.7 20.3 29.7 4.8 32.6 15.4 16.3 7.3 13.0 19.4 9.4 12.0 21.5 10.8 32.1 12.9 13.8 107.4 32.7 30.7 17.9 8.7 6.6 12.1 11.6 33.1 1.1 9.6 26.4 130.0 22.2 6.8 5.5 7.4 11.5 2.2 3.2 3.1 49.6 209.6 22.7 3.1 2.1 8.9 158.6 19.2 4.8 123.5 62.9 87.6 97.0 1.6 2.6 147.9 83.1 5.6 4.9 8.1 7.9 7.3 10.4 132.2 118.2 298.5 13.3 4.4 135.2 51.8 117.9 29.5 34.5 5.1 110.1 98.3 32.0 3.5 1.1 3.1 0.9 2.9 9.1 22.6 16.3 34.6 12.2 4.2 33.5 20.4 28.5 20.7 9.4 33.8 12.4 57.5 7.4 1.3 3.1 1.2 7.5 1.6 6.6 3.8 4.4 4.0 5.2 6.0 8.7 7.6 1.4 3.4 2.2 10.0 1.7 2.9 31.6 31.8 28.8 60.6 29.3 32.3 35.3 32.5 32.6 32.1 32.7 33.1 18.1 9.6 16.4 19.9 9.0 15.9 27.6 12.8 17.6 3.5 18.9 17.5 11.1 27.1 16.2 46.0 0.0 0.6 6.4 22.7 68.4 12.8 24.5 44.0 11.0 18.1 17.4 64.8 11.6 18.7 0.4 15.4 16.8 31.1 13.3 39.4 22.1 87.2 15.7 1.7 16.5 34.2 28.5 11.3 10.8 79.7 29.5 10.2 8.8 13.1 2.9 25.8 7.2 25.6 8.5 7.1 19.6 41.0 9.6 15.0 27.4 113.6 55.9 1.7 46.0 13.3 19.6 18.9 8.7 32.8 14.9 0.4 8.3 31.0 45.0 24.4 HNRNPLL HNRPLL ENSG00000143889 "Heterogeneous nuclear ribonucleoprotein L like" Q8WVV9 2 38561969-38603586 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 155.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046084 Approved Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Mitochondria, Cytosol" "HPA046084: AB_10960895" "unprognostic (2.27e-2)" "unprognostic (1.75e-1)" "unprognostic (3.63e-2)" "unprognostic (5.18e-1)" "unprognostic (2.10e-3)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.22e-4)" "unprognostic (1.52e-2)" "unprognostic (1.52e-1)" "unprognostic (1.80e-1)" "unprognostic (4.20e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (2.25e-1)" "unprognostic (2.28e-1)" "unprognostic (1.26e-1)" "unprognostic (9.30e-2)" 16.0 16.4 16.3 12.5 20.7 51.7 14.7 19.3 21.3 16.2 12.9 16.1 15.5 18.2 13.9 10.2 16.7 14.1 12.8 28.6 8.3 11.1 10.8 16.4 12.5 5.9 8.1 16.9 15.9 16.8 9.2 13.1 7.2 13.9 11.8 26.6 12.8 15.0 13.8 11.4 12.7 12.8 7.8 12.0 15.7 22.6 9.3 31.0 17.7 11.9 9.6 15.2 12.8 15.8 36.7 16.9 48.2 28.4 22.9 21.6 30.1 33.8 27.5 28.8 24.1 19.0 20.7 0.5 29.5 30.4 30.9 23.0 30.7 25.4 29.6 54.6 26.8 26.7 32.3 48.6 21.6 49.9 26.4 16.9 19.6 24.0 26.5 28.5 30.6 23.9 45.9 79.7 34.3 17.2 54.9 27.2 48.4 35.2 30.6 10.6 33.9 18.1 25.0 47.2 32.9 36.9 29.8 25.8 26.0 26.7 21.8 21.6 32.0 21.5 32.1 23.8 28.1 43.4 46.9 0.3 18.5 12.2 26.8 10.6 6.3 9.7 10.3 3.2 17.9 0.4 24.2 18.9 12.0 1.9 7.2 4.6 4.2 6.8 1.2 0.2 38.5 5.8 16.3 20.7 19.3 21.3 28.6 8.3 5.9 8.1 7.2 7.8 9.3 15.8 17.0 19.2 23.4 26.8 5.5 28.7 35.2 16.5 33.0 13.3 18.0 15.2 18.8 8.6 18.8 27.6 8.4 26.2 6.4 13.9 19.6 22.4 155.6 18.1 18.8 20.1 14.4 22.5 68.6 24.3 28.9 26.0 32.1 11.6 9.5 26.3 22.5 7.4 24.4 6.7 40.1 15.4 6.1 15.0 90.2 48.7 27.7 23.1 39.2 37.5 24.5 22.3 2.1 48.7 28.4 21.2 14.2 52.3 23.0 23.6 16.6 18.6 14.5 11.7 39.5 22.6 28.4 91.1 28.8 19.4 21.3 22.2 48.0 22.3 18.8 21.4 HOATZ "C11orf88, FLJ46266" ENSG00000183644 "HOATZ cilia and flagella associated protein" Q6PI97 11 111514785-111537031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 32.5;fallopian tube: 88.9;testis: 29.2" "Cell type enriched" "Detected in single" 28 "Cardiomyocytes: 5.8" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;Karpas-707: 1.7;SuSa: 1.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 8.9" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 2: Karpas-707 - Immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (2.25e-1)" "unprognostic (3.07e-5)" "unprognostic (3.85e-4)" "unprognostic (4.16e-2)" "unprognostic (4.44e-5)" "unprognostic (2.56e-3)" "unprognostic (6.91e-2)" "unprognostic (5.49e-3)" "unprognostic (2.86e-1)" "unprognostic (9.96e-3)" "unprognostic (2.70e-1)" "unprognostic (4.40e-2)" "unprognostic (6.80e-3)" "unprognostic (7.57e-2)" "unprognostic (6.22e-2)" "unprognostic (8.45e-2)" "unprognostic (1.11e-1)" 0.0 0.0 2.1 0.1 2.2 0.1 0.0 1.0 0.5 6.9 32.5 0.0 0.2 3.1 0.4 0.0 88.9 0.2 0.0 2.2 2.7 0.0 0.0 11.6 0.1 9.7 12.4 0.1 0.0 0.0 0.4 0.3 7.6 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.0 6.7 0.2 0.1 29.2 2.1 0.1 0.8 0.0 0.0 0.0 0.0 5.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.3 0.0 0.0 0.2 0.2 0.1 0.3 0.9 0.1 0.0 0.1 0.1 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 2.1 2.2 1.0 0.5 2.2 2.7 9.7 12.4 7.6 6.7 2.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HOMER2 "CPD, Cupidin, DFNA68, HOMER-2, HOMER-2A, HOMER-2B, Vesl-2" ENSG00000103942 "Homer scaffold protein 2" Q9NSB8 15 82836946-82986153 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 226.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 215.9;Endometrial ciliated cells: 184.4;Glandular and luminal cells: 151.9" "Cancer enhanced" "Detected in many" "prostate cancer: 15.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 52.7;Karpas-707: 92.6;SCLC-21H: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040134, CAB079014" Uncertain Supported Supported Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol "CAB079014: , HPA040134: AB_10795272" "unprognostic (7.34e-2)" "unprognostic (3.58e-2)" "unprognostic (5.75e-4)" "unprognostic (3.31e-3)" "unprognostic (4.85e-2)" "unprognostic (1.24e-1)" "unprognostic (1.04e-2)" "unprognostic (7.13e-3)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (2.75e-1)" "unprognostic (8.16e-4)" "unprognostic (2.30e-1)" "unprognostic (3.21e-2)" "unprognostic (1.26e-1)" "unprognostic (4.45e-3)" 1.5 6.3 6.5 1.1 7.6 4.6 26.9 8.2 12.8 23.1 69.8 3.2 8.5 8.4 33.7 21.2 25.9 12.8 21.9 16.2 7.8 7.2 46.4 5.3 1.3 5.7 4.6 2.6 226.2 5.1 7.7 0.6 5.7 57.7 1.0 6.4 71.2 4.6 108.7 45.0 1.3 1.4 4.1 4.8 55.4 6.1 6.0 3.0 28.9 55.9 3.6 1.3 11.7 8.0 16.6 6.9 7.2 18.9 0.2 0.1 1.1 1.1 0.0 1.7 0.6 1.2 11.5 0.1 8.8 8.4 8.3 9.1 52.7 24.9 1.2 45.1 33.5 10.6 0.4 8.3 0.7 0.4 32.6 1.8 37.4 0.6 2.1 1.9 0.0 20.6 0.4 92.6 7.0 48.4 3.2 1.1 11.4 1.4 5.1 2.2 11.5 5.5 25.3 20.1 50.8 13.1 18.6 14.1 17.6 5.2 17.1 3.5 0.2 17.2 31.7 1.3 15.3 11.8 5.9 1.8 29.0 0.4 6.4 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.3 0.1 0.0 0.4 0.0 0.0 0.5 0.2 0.3 6.5 7.6 8.2 12.8 16.2 7.8 5.7 4.6 5.7 4.1 6.0 8.0 1.9 16.0 10.1 24.8 3.8 4.6 56.1 7.2 10.2 15.0 39.7 20.4 23.0 215.9 14.6 11.0 18.8 1.1 4.4 0.3 7.9 29.6 1.9 184.4 15.4 12.4 3.0 8.2 24.8 76.5 0.4 3.6 14.3 151.9 0.0 11.9 1.4 59.6 13.3 20.2 35.1 0.4 0.0 3.2 73.9 4.0 1.8 9.2 37.4 7.5 7.9 18.5 1.0 6.6 11.8 25.9 0.1 0.7 4.1 81.5 0.7 12.1 4.0 5.1 0.0 7.8 4.8 5.5 16.6 19.4 6.0 0.7 3.1 4.1 0.4 30.5 HPS1 "BLOC3S1, HPS" ENSG00000107521 "HPS1 biogenesis of lysosomal organelles complex 3 subunit 1" Q92902 10 98416198-98446935 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Guanine-nucleotide releasing factor" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061260 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA061260: AB_2684459" "unprognostic (1.31e-1)" "prognostic favorable (3.37e-5)" "unprognostic (8.95e-2)" "prognostic favorable (2.93e-5)" "prognostic unfavorable (6.54e-4)" "unprognostic (2.19e-1)" "unprognostic (9.38e-3)" "prognostic favorable (1.26e-4)" "unprognostic (2.39e-1)" "unprognostic (2.44e-3)" "unprognostic (5.64e-3)" "unprognostic (2.24e-1)" "unprognostic (1.76e-1)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "unprognostic (3.06e-2)" "unprognostic (8.30e-3)" 16.8 22.2 12.9 13.4 12.7 37.2 15.3 12.0 15.2 15.6 14.5 18.7 18.4 14.1 6.2 14.1 13.9 13.9 13.2 13.4 12.7 16.3 19.9 16.4 21.3 13.5 12.9 12.3 21.8 6.2 13.4 8.9 13.3 16.1 9.1 2.1 20.4 10.4 7.3 16.2 24.4 7.9 12.6 25.2 18.4 12.8 14.2 10.7 12.7 3.3 12.1 16.3 14.1 12.4 16.9 15.3 1.2 20.6 16.6 19.6 9.4 13.4 43.4 14.3 22.0 10.5 14.7 17.4 16.6 16.3 19.8 20.1 7.7 7.6 6.5 31.4 17.4 27.1 10.0 20.5 37.7 22.0 50.6 21.9 21.1 15.3 19.5 16.7 18.1 11.3 12.0 29.5 15.1 24.0 8.0 18.4 4.2 11.8 9.4 12.8 0.0 12.7 16.6 19.0 3.2 12.3 9.7 7.2 27.6 7.9 16.9 23.5 28.9 10.8 13.8 23.8 14.5 17.3 12.3 12.9 33.0 35.4 12.6 20.2 19.3 36.5 11.3 27.5 11.4 12.4 8.9 10.3 22.6 12.4 6.1 7.4 13.5 16.9 27.4 16.0 14.6 13.6 12.9 12.7 12.0 15.2 13.4 12.7 13.5 12.9 13.3 12.6 14.2 12.4 16.8 19.2 23.8 17.6 49.9 22.3 48.2 40.8 46.1 3.7 40.5 43.9 24.2 28.6 30.2 23.9 2.1 28.3 33.7 72.0 19.6 50.7 33.5 12.4 18.3 18.5 27.1 83.9 11.4 50.3 29.7 27.9 43.8 14.1 29.8 11.6 28.9 26.6 80.6 0.0 14.1 37.5 22.4 62.6 48.7 56.8 27.7 57.4 35.6 12.2 78.6 17.8 60.8 5.5 18.1 60.5 83.0 26.7 43.7 47.7 80.7 59.3 14.7 3.1 13.1 22.3 22.4 28.6 9.5 33.3 18.0 24.6 39.7 41.3 33.1 69.2 HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 16.4;Kupffer cells: 41.5;Macrophages: 20.2;monocytes: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.5" "Group enriched" "Detected in many" 4 "granulocytes: 18.5;monocytes: 27.2" "Cell line enhanced" "Detected in many" "Karpas-707: 39.8;OE19: 40.1;TIME: 25.8" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" No No 6500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" 3.4 4.5 0.8 6.6 0.9 2.3 1.0 0.6 1.7 2.4 0.4 5.9 2.1 2.7 0.2 9.9 3.9 2.7 0.8 0.9 0.9 1.6 2.4 3.2 4.5 1.8 1.0 4.5 0.8 5.6 1.2 2.1 1.3 0.6 6.4 0.2 9.7 0.6 0.3 5.3 2.8 1.9 1.8 6.0 2.0 5.7 2.7 2.0 0.7 0.3 3.9 3.0 3.3 3.6 13.5 0.6 0.1 1.7 3.2 0.9 0.1 1.5 8.2 3.6 16.5 0.0 11.0 0.4 2.3 4.2 20.8 12.3 16.8 2.5 6.5 1.4 1.7 4.2 9.0 0.2 1.4 2.5 8.4 1.8 5.1 2.4 15.4 1.4 18.1 2.4 0.1 39.8 1.5 2.8 0.2 0.3 0.7 40.1 2.6 0.0 0.4 0.6 10.2 0.3 9.3 0.0 17.7 9.8 1.4 2.6 1.5 3.8 25.8 1.5 4.6 1.4 1.7 0.5 6.2 0.2 9.9 11.4 2.7 0.4 27.2 0.0 1.4 10.1 1.0 0.2 2.7 1.0 3.0 0.3 1.7 1.6 18.5 2.3 1.5 0.1 5.2 7.9 0.8 0.9 0.6 1.7 0.9 0.9 1.8 1.0 1.3 1.8 2.7 3.6 0.3 6.4 4.4 0.0 0.7 3.4 3.0 3.3 2.8 0.0 0.3 0.5 0.6 0.0 5.6 1.8 0.0 0.5 2.4 10.1 0.0 1.9 0.6 2.3 3.7 1.0 6.6 2.7 0.8 1.3 2.9 1.4 4.1 13.2 0.0 0.4 2.9 0.6 16.4 0.0 3.8 2.8 0.0 41.5 3.0 0.3 0.6 20.2 0.0 7.5 33.9 0.0 3.1 0.0 0.1 1.1 6.7 0.0 0.7 1.7 4.1 0.0 2.8 0.0 0.0 0.1 1.2 0.2 1.0 4.0 3.7 1.5 6.2 1.4 4.6 3.7 HSD17B14 "DHRS10, retSDR3, SDR47C1" ENSG00000087076 "Hydroxysteroid 17-beta dehydrogenase 14" Q9BPX1 19 48813018-48836510 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 78.2;Hofbauer cells: 149.9;Proximal tubular cells: 434.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 3.7;NK-cells: 4.7;T-cells: 3.1" "Cell line enhanced" "Detected in many" "GAMG: 53.9;HHSteC: 49.5;hTERT-RPE1: 37.9;Karpas-707: 50.7;RT4: 40.5" "Not detected" "Not detected" HPA021467 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA021467: AB_1847652" "unprognostic (2.03e-1)" "unprognostic (7.94e-3)" "prognostic unfavorable (4.39e-5)" "unprognostic (4.32e-2)" "unprognostic (8.03e-2)" "unprognostic (1.47e-1)" "unprognostic (7.54e-2)" "unprognostic (7.76e-3)" "unprognostic (2.71e-1)" "unprognostic (4.04e-1)" "prognostic favorable (2.87e-5)" "unprognostic (4.56e-1)" "unprognostic (5.50e-3)" "unprognostic (9.05e-3)" "unprognostic (1.01e-1)" "unprognostic (5.51e-2)" "unprognostic (1.81e-2)" 9.2 39.5 38.1 3.2 36.3 1.2 11.2 42.8 47.7 34.1 72.5 10.5 3.3 31.6 5.6 4.2 22.7 11.6 8.1 37.2 38.2 58.2 78.8 13.1 8.0 35.6 41.2 56.2 6.2 46.7 24.1 7.3 35.3 15.0 1.9 10.0 6.4 9.2 1.3 7.7 8.2 8.5 35.8 8.7 8.6 4.8 43.6 9.6 25.3 2.2 3.8 15.8 14.6 37.0 0.1 14.0 14.1 2.4 15.8 2.6 0.3 2.6 19.9 1.1 1.2 13.4 0.2 8.0 14.2 0.6 53.9 0.1 1.3 0.1 1.3 0.5 1.0 4.1 0.3 1.8 49.5 0.0 20.9 19.0 0.5 1.2 0.5 37.9 18.1 4.8 0.1 50.7 0.1 0.5 1.1 0.4 1.2 8.2 9.3 7.9 0.1 1.5 0.0 40.5 3.5 9.0 0.0 1.8 10.9 6.0 0.4 0.5 0.0 0.3 5.2 0.5 0.1 8.9 18.9 0.6 11.9 1.2 0.1 0.0 0.0 0.0 0.9 0.0 1.5 3.7 1.5 0.7 0.0 2.5 3.1 2.3 0.0 4.7 0.0 0.5 0.5 0.8 38.1 36.3 42.8 47.7 37.2 38.2 35.6 41.2 35.3 35.8 43.6 37.0 3.3 3.2 11.5 21.5 6.0 2.5 3.6 1.7 0.0 5.5 1.3 5.0 2.0 1.5 4.4 7.3 0.0 1.4 0.3 0.0 78.2 1.9 0.4 0.3 3.5 8.2 13.2 5.3 5.0 1.1 3.0 14.1 2.0 0.7 7.0 7.4 28.5 32.0 149.9 11.8 5.0 0.3 8.2 13.4 9.5 1.4 4.1 17.3 21.4 6.5 8.0 53.5 1.0 4.5 0.8 2.6 0.0 7.2 0.1 3.8 2.2 434.5 0.7 1.6 0.0 2.4 2.9 5.6 15.7 0.3 1.8 2.2 2.8 7.5 0.2 2.9 HSPA13 STCH ENSG00000155304 "Heat shock protein family A (Hsp70) member 13" P48723 21 14371115-14383484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 231.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014797 Approved "Intracellular and membrane" NA NA 3300000 "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA014797: AB_1857567" "unprognostic (2.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (5.77e-3)" "unprognostic (1.06e-1)" "unprognostic (1.72e-1)" "unprognostic (2.85e-3)" "unprognostic (1.41e-2)" "unprognostic (7.86e-2)" "unprognostic (1.64e-1)" "unprognostic (2.46e-1)" "unprognostic (5.62e-2)" "unprognostic (1.52e-2)" "unprognostic (1.65e-1)" "unprognostic (2.29e-1)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" 13.5 24.0 12.3 17.7 14.3 23.5 15.7 11.1 16.0 19.1 8.4 12.4 10.0 21.9 26.4 9.1 8.5 12.3 13.8 13.9 21.1 16.3 13.3 12.9 15.8 12.6 14.0 16.4 9.3 24.0 17.3 22.8 17.0 15.4 12.6 23.3 9.4 16.9 3.4 3.8 10.0 19.2 13.8 15.1 12.7 22.7 16.7 16.9 27.7 8.0 17.4 18.4 5.0 13.4 21.2 17.0 65.7 38.2 46.6 37.4 41.8 58.6 68.9 47.8 54.5 16.1 22.8 36.7 40.3 42.4 71.1 9.1 30.8 20.1 79.6 38.5 24.0 35.8 16.4 30.4 119.5 58.8 44.0 33.4 64.4 68.4 117.0 60.5 40.6 32.6 30.5 231.9 52.7 21.2 39.6 17.9 49.0 9.9 23.2 36.6 57.8 81.2 25.1 8.1 15.0 36.7 43.6 22.6 84.6 33.4 31.1 38.7 40.7 62.1 51.7 49.3 43.4 87.5 70.5 29.2 69.9 37.2 79.5 23.1 4.8 4.9 6.6 5.4 11.4 7.1 7.0 7.1 5.5 3.7 7.7 7.4 1.9 12.1 4.9 8.3 6.0 6.1 12.3 14.3 11.1 16.0 13.9 21.1 12.6 14.0 17.0 13.8 16.7 13.4 14.0 9.6 14.1 11.4 29.7 12.7 14.7 16.9 20.5 41.0 15.6 8.6 14.6 4.3 10.8 3.7 14.6 22.1 25.1 5.1 0.0 8.6 6.8 6.6 31.4 14.6 14.9 26.7 21.0 10.4 31.1 26.4 5.6 15.1 19.0 21.2 12.5 11.8 14.5 60.6 28.2 8.1 4.1 15.8 28.9 2.8 9.9 16.7 23.2 12.2 8.6 34.8 8.2 31.7 15.5 9.3 3.7 19.2 131.4 15.2 2.9 7.5 7.8 21.9 13.1 23.6 25.0 40.2 12.7 12.9 10.2 64.2 24.6 11.9 4.1 13.6 HSPA1B HSP70-2 ENSG00000204388 "Heat shock protein family A (Hsp70) member 1B" P0DMV9 6 31827738-31830254 "Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 3007.4;Urothelial cells: 1619.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 204.3" "CAB008640, HPA052504" Approved Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cytosol" Nucleoplasm "CAB008640: AB_1617331, HPA052504: AB_2681854" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (4.23e-3)" "unprognostic (3.23e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (2.76e-3)" "unprognostic (9.50e-2)" "unprognostic (3.45e-1)" "unprognostic (4.42e-2)" "unprognostic (6.92e-2)" "unprognostic (4.88e-2)" "unprognostic (5.74e-2)" "unprognostic (1.15e-1)" "unprognostic (9.17e-3)" "unprognostic (4.69e-2)" "unprognostic (5.99e-2)" 526.3 340.1 0.7 0.4 1.3 0.0 126.0 1.6 5.6 475.3 0.6 361.2 0.0 154.0 9.1 375.2 231.5 2.3 718.3 1.1 1.9 555.5 685.4 845.3 0.0 0.8 1.0 682.2 336.5 3.3 438.2 0.0 1.2 303.6 0.5 2.6 94.8 0.3 159.9 299.0 139.1 0.0 0.4 274.7 372.0 93.8 1.5 0.0 289.9 0.0 0.0 415.3 503.3 1.2 0.4 24.1 0.4 0.2 1.1 0.0 0.3 0.2 0.0 0.0 0.0 1.0 0.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 0.0 0.0 15.4 0.0 0.5 2.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 204.3 0.0 3.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.5 0.0 1.7 0.0 1.6 0.0 0.0 0.3 3.2 0.0 0.4 41.5 0.4 0.4 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 1.3 1.6 5.6 1.1 1.9 0.8 1.0 1.2 0.4 1.5 1.2 563.2 112.2 75.0 140.7 242.7 239.2 3007.4 63.2 630.0 44.6 509.4 403.9 512.3 40.0 73.7 69.9 131.3 82.7 82.8 542.8 19.6 45.5 1.9 434.9 380.2 446.2 318.6 57.9 2.7 15.6 140.8 585.8 595.8 710.4 346.8 14.1 25.7 17.7 142.0 47.1 2.8 426.3 61.1 84.4 1140.4 9.8 220.6 627.1 642.1 126.5 17.7 192.4 1.0 5.5 61.8 21.4 524.1 54.9 967.0 584.2 159.1 38.3 75.0 144.2 105.2 226.4 846.5 15.2 46.4 904.0 221.9 259.7 604.6 116.7 400.5 1619.4 HSPA6 HSP70B' ENSG00000173110 "Heat shock protein family A (Hsp70) member 6" P17066 1 161524540-161526894 "Plasma proteins, Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 242.2;lung: 94.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 335.3;Langerhans cells: 478.8;Macrophages: 213.7;Prostatic glandular cells: 180.1;Smooth muscle cells: 235.6;T-cells: 391.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 8 "cerebral cortex: 242.2" "Immune cell enriched" "Detected in many" 7 "neutrophil: 317.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 317.9" "Cell line enriched" "Detected in some" 7 "Karpas-707: 50.7" "Low region specificity" "Detected in all" "CAB017452, HPA028549, HPA052504" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles Nucleoplasm "CAB017452: AB_10618032, HPA028549: AB_10601817, HPA052504: AB_2681854" "unprognostic (3.90e-2)" "unprognostic (2.05e-1)" "unprognostic (5.87e-2)" "unprognostic (2.59e-1)" "unprognostic (2.40e-1)" "unprognostic (6.36e-3)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.61e-2)" "unprognostic (1.29e-1)" "unprognostic (1.93e-1)" "unprognostic (1.68e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (1.98e-5)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-2)" "unprognostic (2.04e-1)" 26.2 15.7 11.3 9.9 16.3 3.6 3.6 22.1 242.2 2.9 24.7 9.3 1.7 1.7 0.7 7.3 3.8 8.7 31.7 12.9 12.4 27.2 33.0 94.4 2.3 15.1 12.4 46.8 5.9 1.1 23.8 20.5 28.7 3.3 1.7 1.8 3.3 5.0 3.8 8.4 5.1 2.3 13.8 63.5 34.5 2.4 15.5 1.3 12.8 3.6 1.7 18.5 10.9 20.1 0.8 1.5 0.0 0.3 0.0 1.1 1.0 0.6 0.5 0.2 0.4 0.5 0.7 0.2 2.2 0.2 0.8 0.4 0.5 0.4 0.3 0.5 0.1 0.3 1.4 0.0 0.0 0.1 3.3 0.2 1.0 0.5 0.0 0.0 0.0 0.2 0.6 50.7 0.0 0.0 0.3 1.3 0.1 0.3 5.4 0.0 0.1 0.7 0.0 0.3 0.1 0.0 0.2 0.9 3.1 0.1 0.4 0.7 0.2 0.1 0.5 0.4 3.6 6.9 0.4 0.0 1.3 1.3 2.3 6.5 35.1 13.4 6.4 44.1 1.0 0.2 0.7 3.4 12.2 0.0 0.0 1.6 317.9 8.3 37.7 0.2 0.0 11.8 11.3 16.3 22.1 242.2 12.9 12.4 15.1 12.4 28.7 13.8 15.5 20.1 14.0 9.6 9.3 0.3 23.8 29.3 335.3 4.4 5.2 42.5 8.7 36.2 11.1 0.0 12.2 5.5 127.2 1.8 12.8 25.3 0.0 0.4 3.2 16.2 16.4 36.7 71.0 24.0 0.0 0.0 11.2 98.8 30.1 26.2 2.5 0.0 3.9 0.3 76.0 10.1 0.0 71.0 4.1 47.8 478.8 1.1 5.6 213.7 103.2 1.0 15.8 36.1 5.2 0.0 0.1 0.3 16.5 0.0 104.1 180.1 0.0 1.5 17.1 36.9 0.0 11.1 235.6 2.9 0.6 16.5 21.7 18.3 391.3 3.6 67.3 92.7 ICAM1 "BB2, CD54" ENSG00000090339 "Intercellular adhesion molecule 1" P05362 19 10271093-10286615 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 219.3;urinary bladder: 215.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 612.2;Alveolar cells type 2: 561.6;Endothelial cells: 240.8;Langerhans cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 158.3;Karpas-707: 459.7;RPMI-8226: 148.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002126, CAB002142, HPA004877" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA 87900000 2200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Vesicles, Cytosol" "CAB002142: AB_563596, HPA002126: AB_1078470, HPA004877: AB_1846317" "prognostic favorable (7.09e-4)" "unprognostic (1.88e-1)" "unprognostic (1.94e-1)" "unprognostic (2.63e-2)" "unprognostic (3.25e-3)" "unprognostic (3.05e-1)" "unprognostic (1.45e-2)" "unprognostic (3.48e-1)" "unprognostic (3.18e-2)" "unprognostic (1.09e-2)" "unprognostic (1.49e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.32e-6)" "unprognostic (2.77e-1)" "unprognostic (2.16e-2)" "unprognostic (2.25e-1)" "unprognostic (3.70e-3)" 87.9 23.6 9.1 44.6 9.6 117.1 32.4 7.9 12.0 11.2 9.9 17.7 16.8 23.9 3.5 11.0 26.2 56.4 39.1 8.8 9.9 43.9 67.1 219.3 38.3 12.3 8.7 13.0 11.1 8.3 9.3 27.8 10.2 22.2 18.1 10.5 18.0 6.3 15.1 17.9 22.6 23.4 10.0 55.9 21.5 5.6 15.4 28.4 30.8 12.8 32.9 215.3 12.5 10.2 46.3 0.5 7.9 0.2 2.0 4.4 9.7 8.6 91.6 21.8 62.0 14.0 49.8 39.6 130.3 3.8 99.3 8.9 1.7 0.4 45.6 123.8 0.1 3.8 1.4 62.0 158.3 1.3 23.9 55.7 4.0 13.7 20.3 2.0 10.7 4.9 15.0 459.7 1.5 3.3 0.5 34.9 3.1 0.5 24.7 1.0 0.2 148.5 36.8 0.3 0.3 1.1 61.2 3.3 94.5 3.7 6.9 2.8 34.3 22.3 1.9 12.3 0.8 137.4 142.7 25.5 35.1 26.3 32.6 5.0 28.3 5.2 5.3 25.8 9.8 3.8 4.0 6.3 24.7 1.5 1.9 3.8 40.8 15.2 17.0 14.1 6.1 20.8 9.1 9.6 7.9 12.0 8.8 9.9 12.3 8.7 10.2 10.0 15.4 10.2 150.3 612.2 561.6 0.3 31.7 85.3 22.2 62.6 28.5 0.0 50.2 24.9 1.1 21.5 133.5 3.7 0.0 1.1 28.9 2.9 0.0 176.8 2.0 14.1 15.5 240.8 2.4 1.3 0.5 98.7 3.3 136.6 13.7 29.8 139.8 0.1 48.2 12.1 86.7 0.0 0.4 0.7 32.6 53.6 232.6 1.3 4.7 168.3 76.5 7.5 101.9 4.6 5.2 0.5 0.2 113.7 0.3 1.5 57.6 27.1 0.3 15.0 83.2 0.4 6.6 38.2 57.6 0.8 1.6 4.3 69.3 1.2 28.8 0.5 1.6 14.1 ICAM3 "CD50, CDW50, ICAM-R" ENSG00000076662 "Intercellular adhesion molecule 3" P32942 19 10333776-10339661 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 206.5;liver: 73.2;lymphoid tissue: 85.8" "Cell type enhanced" "Detected in many" "B-cells: 151.9;dendritic cells: 164.6;Hepatocytes: 168.8;NK-cells: 313.1;Plasma cells: 137.2;T-cells: 183.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1948.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 1948.5" "Cell line enhanced" "Detected in many" "Karpas-707: 324.6;NB-4: 222.3;RPMI-8226: 257.6;U-266/84: 188.8;U-937: 179.0" "Not detected" "Not detected" "CAB002498, HPA049820" Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA 390000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "Nucleoplasm, Nuclear membrane" "CAB002498: AB_563593, HPA049820: AB_2680897" "unprognostic (6.85e-4)" "unprognostic (5.28e-3)" "unprognostic (3.09e-3)" "unprognostic (1.57e-2)" "unprognostic (5.34e-3)" "unprognostic (5.79e-6)" "unprognostic (5.05e-3)" "unprognostic (3.73e-2)" "unprognostic (1.73e-3)" "unprognostic (7.93e-2)" "unprognostic (3.45e-2)" "unprognostic (2.54e-1)" "unprognostic (5.62e-4)" "unprognostic (1.13e-1)" "unprognostic (1.06e-2)" "unprognostic (3.43e-1)" "unprognostic (1.84e-1)" 18.9 7.4 4.8 50.4 4.6 206.5 10.0 4.5 6.4 4.9 4.4 16.1 15.1 3.6 2.8 7.6 6.2 9.0 18.1 4.5 4.6 11.9 73.2 16.0 72.2 4.9 5.0 2.9 15.2 2.9 1.0 4.6 5.0 6.8 11.0 0.9 15.2 2.9 18.0 4.3 28.1 4.4 5.2 85.8 19.5 2.1 5.2 48.6 6.8 11.9 50.6 14.1 4.4 4.6 12.4 5.8 4.2 13.1 6.8 5.3 7.3 7.5 5.1 5.9 5.2 5.3 8.1 0.2 24.9 6.2 0.1 5.4 0.2 5.5 2.0 106.2 3.7 23.8 5.4 22.6 3.4 96.7 102.1 4.8 4.4 7.0 2.6 6.4 2.9 57.1 13.0 324.6 6.9 24.0 13.9 222.3 3.2 31.7 38.3 11.1 2.7 257.6 6.2 11.2 1.3 5.6 6.5 20.4 17.3 1.9 17.7 23.9 4.6 28.0 3.0 31.2 7.6 20.7 188.8 37.3 20.2 179.0 22.1 193.6 395.4 872.4 362.7 287.8 436.2 280.1 343.0 331.7 327.5 271.7 301.5 283.9 1948.5 380.1 417.4 52.9 436.3 614.5 4.8 4.6 4.5 6.4 4.5 4.6 4.9 5.0 5.0 5.2 5.2 4.6 22.6 3.2 29.7 0.7 151.9 8.2 6.5 7.0 10.2 0.3 23.1 20.6 0.1 21.5 9.8 5.5 0.0 12.0 164.6 49.1 62.6 16.9 7.7 10.7 9.4 19.2 5.4 37.4 0.2 35.4 24.7 10.2 16.8 9.9 30.4 5.5 31.1 168.8 24.0 1.7 0.1 33.2 4.1 70.0 50.4 10.0 6.2 52.9 55.2 1.0 127.7 6.4 313.1 0.0 0.1 23.2 43.8 4.1 137.2 12.3 79.9 54.4 9.0 1.2 0.0 7.3 10.7 5.7 0.7 8.3 8.4 4.7 183.3 5.4 36.4 10.2 IFI27L1 FAM14B ENSG00000165948 "Interferon alpha inducible protein 27 like 1" Q96BM0 14 94081301-94103846 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 97.6" "Cell type enhanced" "Detected in all" "Early spermatids: 328.4;Late spermatids: 160.8;Theca cells: 125.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 16.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 202.4" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (7.89e-3)" "unprognostic (1.47e-1)" "unprognostic (6.31e-2)" "unprognostic (8.54e-3)" "unprognostic (2.53e-1)" "unprognostic (4.81e-2)" "unprognostic (1.84e-2)" "unprognostic (2.63e-1)" "unprognostic (3.68e-1)" "unprognostic (7.63e-3)" "unprognostic (2.50e-1)" "unprognostic (2.00e-1)" "unprognostic (3.90e-2)" "unprognostic (3.50e-2)" "unprognostic (1.71e-1)" "unprognostic (5.93e-3)" "unprognostic (2.92e-1)" 15.7 51.0 28.6 6.6 28.3 20.0 13.1 28.6 31.6 11.3 33.4 14.0 11.9 10.2 23.0 11.5 11.3 9.5 17.1 28.4 30.5 14.3 10.6 13.9 6.8 29.6 30.0 28.5 9.5 12.8 13.3 4.5 30.2 7.5 13.8 17.2 11.8 7.2 20.1 13.1 12.6 9.6 28.6 12.6 16.5 97.6 30.2 12.9 9.2 14.4 10.2 6.6 11.0 29.8 16.8 16.3 23.9 23.7 29.6 27.2 10.9 20.2 21.8 19.5 47.0 5.5 38.1 16.1 31.5 16.5 20.4 17.7 3.5 12.0 13.9 43.0 20.0 14.1 34.4 10.9 14.4 16.9 15.6 25.3 14.0 22.0 15.6 33.0 15.7 70.8 28.8 202.4 32.3 14.6 18.5 16.0 8.1 32.3 13.9 33.6 21.1 25.4 23.4 3.1 20.7 11.3 35.1 15.8 29.4 16.0 22.4 27.3 17.4 9.6 7.4 19.0 15.2 43.6 46.3 24.4 31.4 18.4 12.3 16.2 1.6 2.3 2.3 1.8 2.1 2.4 4.0 3.2 1.5 2.8 2.7 3.3 0.8 3.9 1.6 4.6 5.4 1.6 28.6 28.3 28.6 31.6 28.4 30.5 29.6 30.0 30.2 28.6 30.2 29.8 28.7 28.9 13.7 15.7 15.3 17.1 22.9 34.4 18.2 17.9 20.7 21.5 18.8 14.3 23.0 20.2 10.4 19.3 11.1 53.5 27.4 27.4 328.4 33.7 14.4 20.1 15.5 12.8 4.6 26.7 14.0 26.5 23.4 18.8 5.7 72.2 30.4 14.3 35.7 13.5 5.5 59.4 44.7 10.0 12.2 160.8 42.6 11.8 26.6 3.7 5.5 44.6 14.4 6.0 7.5 26.2 43.5 57.2 44.7 13.6 88.1 33.5 20.0 30.1 13.1 11.7 17.6 30.0 39.0 21.6 14.2 7.1 14.0 125.3 31.6 23.8 IFI27L2 "FAM14A, TLH29" ENSG00000119632 "Interferon alpha inducible protein 27 like 2" Q9H2X8 14 94127779-94130253 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 446.8" HPA049588 Approved Nucleoli,Cytosol "Intracellular and membrane" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Nucleoli "HPA049588: " "unprognostic (9.70e-3)" "unprognostic (2.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.76e-1)" "unprognostic (2.45e-1)" "unprognostic (2.80e-2)" "unprognostic (7.46e-3)" "unprognostic (4.76e-2)" "unprognostic (4.69e-2)" "unprognostic (1.58e-2)" "unprognostic (4.79e-3)" "unprognostic (3.96e-2)" "unprognostic (8.13e-2)" "unprognostic (2.03e-1)" "unprognostic (3.88e-1)" "unprognostic (5.09e-2)" "unprognostic (3.52e-2)" 47.8 114.5 148.9 42.4 157.0 46.6 43.1 159.2 207.3 76.4 142.8 57.3 22.5 51.5 14.5 73.9 54.1 46.4 108.2 149.3 169.0 68.2 10.2 60.0 57.9 162.6 152.7 78.8 27.8 55.0 83.3 10.7 162.3 35.8 20.4 51.6 26.7 21.6 8.8 52.5 52.8 25.6 160.9 72.2 35.5 31.1 160.1 46.9 35.1 9.9 50.5 41.6 72.1 171.9 61.5 39.3 10.8 90.8 70.1 166.5 7.6 118.1 129.9 92.3 99.6 12.1 28.0 29.0 128.3 134.2 59.1 81.6 8.8 150.5 36.8 185.4 3.0 44.0 41.0 4.6 98.5 53.2 116.7 163.1 55.8 50.5 39.0 162.6 49.1 108.5 3.8 446.8 107.5 128.3 32.3 33.9 16.4 41.9 49.2 1.9 40.2 42.2 137.8 25.2 24.1 28.7 3.8 0.0 78.4 22.9 146.4 87.6 65.9 61.5 35.0 79.5 30.1 171.8 164.4 10.4 201.7 124.1 39.2 167.4 238.3 48.0 153.4 167.9 99.4 214.2 140.6 168.4 184.2 201.3 104.2 134.9 37.6 44.3 121.5 153.5 203.5 217.4 148.9 157.0 159.2 207.3 149.3 169.0 162.6 152.7 162.3 160.9 160.1 171.9 86.5 38.5 50.9 10.1 71.8 92.8 73.1 218.3 111.0 27.2 47.9 103.6 162.8 50.1 55.8 178.4 20.9 2.3 79.3 58.2 178.1 159.2 8.2 78.1 113.7 70.1 99.6 20.6 1.6 29.1 2.7 133.0 43.8 11.6 90.7 64.8 121.1 4.2 190.8 23.5 3.6 193.8 57.0 163.7 107.6 31.1 183.0 119.1 236.5 0.0 134.7 181.0 137.0 5.5 13.9 68.1 150.2 115.5 104.4 23.7 125.6 113.3 61.8 113.3 124.9 70.4 87.7 8.3 22.1 105.2 66.9 2.9 92.2 92.7 82.8 55.9 IFITM5 "BRIL, DSPA1, fragilis4, Hrmp1" ENSG00000206013 "Interferon induced transmembrane protein 5" A6NNB3 11 298200-299526 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Mineral balance" "Developmental protein" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 4.9;pancreas: 7.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 8 "cerebral cortex: 4.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039258 Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Cytosol" "HPA039258: AB_10673608" "unprognostic (9.84e-2)" "unprognostic (2.15e-1)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (7.46e-2)" "unprognostic (4.20e-2)" "unprognostic (4.42e-2)" "unprognostic (8.31e-2)" "unprognostic (7.99e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (4.90e-2)" 0.1 0.0 0.0 0.1 0.0 0.7 0.2 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.1 0.1 0.1 0.0 7.3 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNAR1 "IFNAR, IFRC" ENSG00000142166 "Interferon alpha and beta receptor subunit 1" P17181 21 33324429-33359864 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029226 Approved NA NA 170000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA029226: AB_2672954" "unprognostic (2.42e-3)" "unprognostic (2.95e-1)" "unprognostic (3.01e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (3.02e-1)" "unprognostic (4.69e-2)" "unprognostic (1.28e-1)" "unprognostic (2.31e-2)" "unprognostic (2.38e-1)" "unprognostic (9.38e-3)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (8.45e-2)" "unprognostic (3.06e-2)" 40.8 22.3 14.3 36.4 14.6 30.8 32.3 15.7 15.2 26.3 9.6 28.9 26.7 22.4 23.2 25.2 23.8 30.2 21.2 15.0 16.2 32.0 76.6 29.7 28.8 17.4 15.6 23.5 29.2 40.5 7.7 49.5 16.9 27.2 30.5 23.6 30.2 24.1 32.7 20.5 27.4 24.0 15.7 33.5 31.6 20.9 17.5 33.1 41.2 24.8 29.7 39.8 9.0 18.6 47.3 24.4 27.4 24.2 55.8 80.8 23.7 44.6 74.2 32.9 36.1 31.7 57.2 42.4 35.4 49.4 36.3 28.4 23.3 37.0 43.8 33.8 26.0 62.8 29.0 20.2 33.9 50.8 43.3 58.2 38.4 43.6 37.7 39.4 63.1 40.3 67.6 198.2 56.5 22.8 38.7 22.2 24.9 46.6 25.6 29.5 75.0 62.4 33.7 44.0 22.5 24.1 50.5 42.4 39.3 20.8 58.2 36.8 61.3 39.3 24.7 58.2 28.2 102.3 132.7 43.2 66.3 64.4 50.5 77.3 45.4 27.7 23.6 64.0 23.1 56.2 31.5 28.6 37.4 57.0 37.0 29.0 166.7 28.0 80.3 54.3 41.2 35.2 14.3 14.6 15.7 15.2 15.0 16.2 17.4 15.6 16.9 15.7 17.5 18.6 101.2 109.0 45.8 17.6 69.3 45.8 57.0 72.3 18.8 51.9 42.5 29.7 33.5 34.3 78.8 44.1 29.2 28.1 43.8 25.3 21.5 73.0 17.7 37.9 58.4 75.5 26.9 27.1 26.3 90.5 92.4 61.1 35.7 44.5 39.2 30.3 53.9 81.3 69.2 58.9 29.4 28.9 46.8 82.1 47.5 10.7 32.6 77.6 37.4 30.9 86.8 34.3 42.2 34.2 27.2 64.7 25.5 30.9 137.3 63.9 37.6 28.7 59.6 30.0 19.7 54.9 44.9 38.5 17.5 21.5 44.9 20.1 38.3 25.1 27.5 72.2 IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 629.4" "Cell type enriched" "Detected in some" 335 "Plasma cells: 13473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory B-cell: 52.8;naive B-cell: 27.8" "Lineage enriched" "Detected in many" 9 "B-cells: 52.8" "Cell line enriched" "Detected in some" 11 "Karpas-707: 148.5" "Immunoglobulin genes" NA NA 2600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-2)" "unprognostic (3.81e-3)" "unprognostic (2.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.41e-3)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (5.60e-2)" "unprognostic (3.07e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.67e-7)" "unprognostic (7.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-1)" "unprognostic (3.26e-1)" 10.6 59.3 0.0 207.8 0.0 36.4 46.7 0.0 0.5 41.6 0.3 193.3 218.5 4.8 15.3 45.5 6.5 85.4 3.2 0.0 0.1 8.2 8.9 40.9 171.8 0.2 0.0 8.4 7.0 0.3 0.6 0.1 0.1 6.0 223.2 0.0 120.6 23.5 0.6 0.9 140.9 11.2 0.0 246.6 189.1 0.4 0.1 57.8 24.2 0.0 629.4 92.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 14.1 1.0 148.5 0.0 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.7 0.7 0.0 0.0 10.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.7 0.0 2.8 1.4 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 52.8 0.6 0.2 0.0 27.8 1.6 0.5 0.0 0.0 0.0 5.8 1.7 6.1 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13473.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 4.5 0.0 0.0 0.0 IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 465.8;lymphoid tissue: 1426.6;stomach 1: 707.9" "Cell type enriched" "Detected in some" 333 "Plasma cells: 9414.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory B-cell: 66.7;naive B-cell: 67.3" "Lineage enriched" "Detected in many" 22 "B-cells: 67.3" "Cell line enriched" "Detected in some" 5 "Karpas-707: 8.8" "Immunoglobulin genes" NA NA 700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (6.62e-3)" "prognostic favorable (1.41e-4)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.63e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" 16.9 5.0 0.0 183.0 0.2 112.8 106.0 0.0 0.5 45.0 0.2 465.8 266.6 7.5 2.5 27.9 10.7 65.0 5.8 0.0 0.1 20.9 16.4 83.9 188.0 0.5 0.2 13.8 9.3 1.0 1.1 0.3 0.7 9.4 296.3 0.0 201.4 8.8 0.4 2.9 177.0 17.4 0.3 351.0 707.9 2.3 0.0 121.5 27.6 0.0 1426.6 249.3 12.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.6 0.4 0.0 0.1 1.2 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.4 0.6 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 66.7 0.0 0.0 0.1 67.3 0.1 0.1 3.0 0.0 0.0 0.0 0.0 10.5 0.0 0.2 0.0 0.5 0.0 0.1 0.5 0.2 0.7 0.3 0.0 0.4 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.1 27.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9414.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 IGHV4-4 ENSG00000276775 "Immunoglobulin heavy variable 4-4" A0A075B6R2 14 106011922-106012420 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 567.7;urinary bladder: 768.4" "Cell type enriched" "Detected in some" 285 "Plasma cells: 2624.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 10 "midbrain: 4.8" "Group enriched" "Detected in some" 23 "memory B-cell: 56.6;naive B-cell: 31.2" "Lineage enriched" "Detected in many" 30 "B-cells: 56.6" "Cell line enriched" "Detected in some" 18 "Karpas-707: 34.5" "Immunoglobulin genes" NA NA 3800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.60e-6)" "unprognostic (2.24e-1)" "unprognostic (6.27e-2)" "unprognostic (1.30e-1)" "unprognostic (2.10e-1)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (3.16e-1)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.05e-1)" 9.4 2.5 0.0 131.4 0.0 17.8 63.6 0.0 0.2 37.5 0.1 205.2 159.9 3.8 0.8 59.8 53.4 104.9 0.9 0.0 0.1 5.5 6.6 36.9 173.2 0.3 4.8 10.0 6.0 0.4 0.4 0.0 0.1 4.0 140.2 0.0 78.2 15.0 0.3 3.8 78.6 13.4 0.4 186.4 175.0 1.6 0.1 31.8 16.7 0.0 567.7 768.4 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 34.5 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 56.6 0.2 0.2 0.0 31.2 0.6 0.0 0.0 0.0 0.0 1.9 0.6 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.3 4.8 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2624.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 IGHV7-4-1 ENSG00000282122 "Immunoglobulin heavy variable 7-4-1" A0A0J9YVY3 14 106025145-106025630 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.4;lymphoid tissue: 133.9" "Cell type enriched" "Detected in some" 4 "Plasma cells: 4.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 109 "memory B-cell: 8.3;naive B-cell: 13.5" "Lineage enriched" "Detected in single" 136 "B-cells: 13.5" "Cell line enriched" "Detected in some" 5 "Karpas-707: 5.4" "Immunoglobulin genes" NA NA 560000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" 3.9 2.9 0.3 58.3 0.0 39.0 21.1 0.0 0.6 7.7 0.2 60.8 8.3 0.5 0.0 4.7 0.8 3.1 0.8 0.0 0.0 2.1 2.8 49.1 7.5 0.0 0.0 0.9 0.7 0.0 0.2 0.0 0.0 2.6 97.4 0.0 42.2 8.7 0.3 0.2 42.9 0.2 0.1 68.5 24.2 0.2 0.0 45.6 5.9 0.0 133.9 10.4 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLC7 ENSG00000211685 "Immunoglobulin lambda constant 7" 22 22922594-22923034 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 88.1;lymphoid tissue: 107.7;salivary gland: 70.1;stomach 1: 113.1" "Cell type enriched" "Detected in some" 10 "B-cells: 109.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 341 "memory B-cell: 128.8;naive B-cell: 133.0" "Lineage enriched" "Detected in single" 346 "B-cells: 133.0" "Cell line enriched" "Detected in some" 913 "Karpas-707: 122629.0" "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.20e-3)" "unprognostic (5.94e-2)" "unprognostic (3.91e-1)" "unprognostic (2.16e-2)" "prognostic favorable (2.03e-4)" "unprognostic (2.11e-1)" "unprognostic (9.60e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (2.74e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (1.61e-6)" "unprognostic (2.86e-1)" "unprognostic (2.14e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-2)" 5.6 4.7 0.0 27.9 0.0 19.9 15.6 0.0 0.4 5.1 0.0 54.1 88.1 4.4 0.5 8.4 4.3 10.7 1.4 0.0 0.5 2.3 3.5 8.3 40.8 0.3 0.0 2.5 1.7 0.1 0.2 0.0 0.2 4.4 23.1 0.0 70.1 0.6 0.1 0.2 23.1 0.9 0.0 107.7 113.1 0.8 0.1 20.0 5.7 0.0 104.2 19.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 112.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122629.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.7 3.0 0.6 111.2 0.0 47.3 0.3 0.1 0.0 0.0 0.1 0.0 128.8 0.0 0.0 0.1 133.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 25.5 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 109.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.5 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1542.6;lymphoid tissue: 2926.9" "Cell type enriched" "Detected in some" 85 "Plasma cells: 7693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1402.5;naive B-cell: 850.1" "Lineage enriched" "Detected in many" 46 "B-cells: 1402.5" "Cell line enhanced" "Detected in some" "Karpas-707: 75.0;U-266/70: 20.9;U-266/84: 15.3" "Immunoglobulin genes" NA NA 980000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.76e-3)" "unprognostic (6.86e-2)" "unprognostic (3.46e-3)" "unprognostic (7.67e-3)" "unprognostic (2.82e-3)" "prognostic favorable (4.74e-5)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (9.19e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (3.93e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (2.27e-1)" 33.6 7.3 0.6 344.7 0.3 157.3 447.8 0.1 2.7 27.7 0.8 1455.8 1542.6 18.4 0.5 212.0 30.0 191.3 44.6 0.2 0.7 22.4 41.1 179.8 680.1 1.5 0.2 30.5 22.4 0.6 2.1 0.5 1.1 17.0 868.3 0.0 425.0 36.0 1.7 2.9 713.8 21.3 0.6 637.7 876.1 75.4 0.5 286.4 62.2 0.0 2926.9 661.1 14.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 3.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 75.0 0.0 0.0 0.9 4.6 1.1 0.0 0.0 0.8 2.8 8.3 0.0 0.0 2.9 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 1.1 0.3 1.6 20.9 15.3 0.0 0.3 1.1 0.0 1.2 1.0 0.7 11.5 0.2 1.4 1402.5 1.5 5.9 0.9 850.1 1.0 4.6 30.2 11.1 0.8 0.9 0.8 149.8 0.6 0.3 0.1 2.7 0.2 0.7 1.5 0.2 1.1 0.6 0.5 2.2 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 15.8 0.0 0.0 0.0 1.4 11.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7693.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 691.1;lymphoid tissue: 1598.0;stomach 1: 672.8" "Cell type enriched" "Detected in some" 132 "Plasma cells: 12487.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 369 "memory B-cell: 2072.7;naive B-cell: 2596.0" "Lineage enriched" "Detected in all" 410 "B-cells: 2596.0" "Cell line enriched" "Detected in some" 10 "Karpas-707: 85411.7" "Immunoglobulin genes" NA NA 540000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" 16.0 38.9 0.7 306.7 0.3 103.6 184.7 0.1 1.5 45.2 0.6 634.1 691.1 16.2 1.3 78.7 25.5 66.8 19.9 0.2 0.1 18.6 26.2 160.8 623.2 1.0 0.1 16.3 8.2 0.6 1.7 0.6 0.4 10.8 457.1 0.0 356.7 38.1 0.5 2.1 517.3 16.1 0.3 530.5 672.8 5.9 0.2 277.6 39.1 0.4 1598.0 274.5 11.9 0.3 0.8 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 65.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 82.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 85411.7 0.0 0.0 2.2 4.2 0.5 0.0 0.0 0.7 1.9 8843.9 0.0 0.0 2.1 4.5 0.0 4.7 0.0 0.0 1.9 0.0 1.0 0.0 1.1 3.4 0.7 213.9 81.1 0.5 92.6 0.2 35.5 1.8 3.1 1.0 1.6 0.9 1.3 2072.7 1.6 0.8 2.6 2596.0 0.6 0.9 6.3 1.6 1.7 0.9 1.3 231.7 0.7 0.3 0.1 1.5 0.2 0.1 1.0 0.1 0.4 0.3 0.2 0.3 0.0 0.0 0.0 0.0 94.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.7 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 39.5 0.0 0.2 0.0 IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6" "Cell type enhanced" "Detected in some" "dendritic cells: 35.1;Kupffer cells: 13.9;NK-cells: 69.0;Plasma cells: 15.3;T-cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 18.8;HDLM-2: 35.2;Karpas-707: 57.8;U-698: 15.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" 2.1 1.2 1.0 15.2 1.8 9.3 0.9 1.0 2.1 1.0 1.7 3.1 4.5 0.7 0.8 1.6 0.8 3.5 0.7 1.1 1.1 0.9 2.2 5.8 24.6 2.5 1.5 0.6 0.5 1.3 0.5 1.6 2.3 0.8 2.9 0.5 1.7 0.6 0.7 1.6 7.0 1.9 1.1 16.2 4.1 0.8 2.3 6.6 0.7 0.2 14.1 4.0 0.5 3.7 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.1 0.5 1.0 0.3 2.2 18.8 0.1 0.2 0.7 0.3 0.0 0.0 0.0 35.2 0.2 2.2 0.6 0.3 1.0 0.9 3.1 0.1 0.0 0.5 0.0 0.2 0.1 5.1 0.3 57.8 0.0 0.2 9.7 0.3 0.1 0.1 0.0 6.7 0.1 0.8 0.0 0.1 0.4 0.0 0.2 0.2 0.2 0.1 0.4 9.7 0.4 0.5 0.4 0.2 0.2 6.6 11.0 15.2 0.6 12.1 1.1 8.5 12.5 9.2 50.9 34.7 64.0 11.5 34.8 41.7 14.7 9.1 19.3 34.0 14.7 40.9 34.0 8.1 53.0 24.3 1.0 1.8 1.0 2.1 1.1 1.1 2.5 1.5 2.3 1.1 2.3 3.7 0.5 0.0 3.0 0.3 9.6 0.3 2.1 0.1 0.6 0.0 0.3 0.5 1.0 1.5 0.6 0.0 0.0 0.2 35.1 0.1 0.0 0.0 0.5 0.5 0.2 0.5 0.0 5.2 0.8 0.0 0.8 0.7 3.1 0.7 4.5 0.0 0.4 0.1 6.4 0.0 0.4 0.0 0.0 13.9 4.0 0.0 0.0 11.7 0.0 3.7 11.9 0.0 69.0 0.0 2.6 0.1 0.0 0.0 15.3 0.5 0.4 0.2 0.2 0.0 0.0 0.7 0.3 0.4 0.1 0.0 0.9 0.1 31.5 0.0 0.2 1.3 IL17A "CTLA8, IL-17, IL-17A, IL17" ENSG00000112115 "Interleukin 17A" Q16552 6 52186375-52190638 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enriched" "Detected in single" 14 "T-cells: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "Karpas-707: 2.7;U-266/84: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA052258 Uncertain "Secreted to blood" NA NA 9920 "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA052258: " "unprognostic (5.55e-1)" "unprognostic (2.18e-4)" "unprognostic (3.05e-4)" "unprognostic (1.41e-2)" "unprognostic (2.22e-2)" 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.2 IL2RG "CD132, CIDX, IMD4, SCIDX1" ENSG00000147168 "Interleukin 2 receptor subunit gamma" P31785 X 71107404-71112108 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 118.0;lymphoid tissue: 346.4" "Cell type enhanced" "Detected in many" "B-cells: 186.1;dendritic cells: 199.0;Distal enterocytes: 202.0;NK-cells: 310.0;Paneth cells: 133.2;Plasma cells: 221.2;T-cells: 289.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "Karpas-707: 2316.2" "HPA046641, HPA049691" Enhanced Approved Vesicles NA NA 13000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" Vesicles "HPA046641: AB_2679733, HPA049691: AB_2680851" "unprognostic (2.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.73e-4)" "unprognostic (8.25e-2)" "unprognostic (1.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.91e-3)" "unprognostic (1.23e-2)" "unprognostic (4.36e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.28e-7)" "unprognostic (1.73e-1)" "unprognostic (4.69e-2)" "unprognostic (4.89e-2)" "unprognostic (9.54e-2)" 12.8 6.2 2.7 132.2 2.4 87.3 14.1 2.5 6.3 10.2 4.0 98.9 50.4 7.5 7.5 15.1 6.8 28.2 4.6 2.3 2.8 7.1 20.6 51.7 235.6 3.6 2.7 4.9 4.1 1.9 1.5 16.9 4.2 7.8 118.0 0.5 19.0 5.9 2.6 15.4 82.8 12.3 3.1 119.4 41.4 2.2 3.0 346.4 5.8 6.3 306.9 46.4 5.5 3.8 1.2 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.0 4.7 9.1 187.3 13.5 0.0 0.7 1.7 0.4 0.0 0.0 160.3 0.2 23.6 0.3 0.3 0.2 99.3 4.0 0.0 0.0 0.0 0.1 0.1 0.0 220.5 43.3 2316.2 0.0 0.0 356.4 193.7 0.4 0.9 0.1 79.5 0.8 20.0 0.0 0.7 0.2 0.3 2.3 0.1 0.5 0.0 0.0 3.5 0.4 0.0 1.0 0.0 0.5 132.1 242.2 119.6 2.1 397.4 0.9 540.5 102.2 169.7 1204.7 239.5 1179.9 604.7 1086.3 1250.7 243.5 603.0 742.0 943.1 773.0 1190.3 177.0 368.9 1422.2 1494.0 2.7 2.4 2.5 6.3 2.3 2.8 3.6 2.7 4.2 3.1 3.0 3.8 3.3 3.2 11.2 0.0 186.1 8.2 8.1 13.1 1.2 0.0 1.5 1.7 0.9 4.3 4.2 0.0 0.0 0.5 199.0 202.0 0.0 1.2 0.1 0.8 0.7 5.8 77.7 27.1 0.0 2.3 0.3 4.2 13.7 0.7 39.3 0.4 6.1 2.1 31.1 0.0 0.0 24.5 4.1 25.2 116.7 0.0 0.0 45.4 42.7 1.0 91.1 0.1 310.0 0.0 0.1 28.0 133.2 0.4 221.2 4.3 88.8 1.1 2.3 0.4 0.0 1.3 2.6 0.0 0.1 1.8 6.8 0.3 289.5 0.0 18.6 8.9 IL32 "NK4, TAIF, TAIFb, TAIFd" ENSG00000008517 "Interleukin 32" P24001 16 3065297-3082192 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 829.3;pancreas: 674.4" "Cell type enhanced" "Detected in many" "Ductal cells: 1696.0;Exocrine glandular cells: 1490.0;Pancreatic endocrine cells: 2546.1;Proximal enterocytes: 4916.6;Proximal tubular cells: 4315.8;T-cells: 1711.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 4625.7" "Lineage enriched" "Detected in all" 8 "T-cells: 4625.7" "Cell line enhanced" "Detected in many" "CACO-2: 514.7;CAPAN-2: 328.6;HDLM-2: 707.9;Hep G2: 504.3;Karpas-707: 404.6;MOLT-4: 319.9;RH-30: 348.0;U-937: 314.5" "HPA029397, CAB030029" Uncertain "Secreted to blood" NA NA 46100 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB030029: AB_1089175, HPA029397: AB_10612120" "unprognostic (2.00e-2)" "unprognostic (2.89e-2)" "unprognostic (2.86e-1)" "prognostic favorable (1.33e-4)" "unprognostic (2.95e-2)" "unprognostic (1.32e-1)" "unprognostic (8.02e-2)" "unprognostic (2.58e-2)" "unprognostic (1.73e-3)" "unprognostic (2.19e-2)" "unprognostic (3.32e-3)" "unprognostic (3.51e-1)" "unprognostic (3.30e-2)" "unprognostic (8.08e-2)" "unprognostic (3.86e-2)" "unprognostic (3.16e-2)" "unprognostic (4.29e-3)" 91.1 36.7 21.3 206.7 21.0 49.1 58.7 20.3 27.6 19.2 19.0 206.5 339.8 30.4 13.5 45.5 20.6 117.4 180.6 19.1 20.0 418.8 829.3 271.5 402.7 24.0 20.4 22.3 674.4 10.2 17.7 62.8 23.0 54.2 142.7 1.0 87.1 42.2 543.7 26.9 558.9 88.4 21.2 440.7 87.4 19.2 24.8 198.0 84.3 328.6 200.2 118.8 23.1 21.3 254.1 10.7 1.2 0.3 0.5 28.4 19.5 12.4 31.3 14.9 24.8 514.7 328.6 0.6 59.8 7.0 92.1 10.7 1.0 29.6 18.0 707.9 2.7 1.2 49.8 504.3 55.7 1.4 20.5 34.2 3.4 12.9 54.9 12.1 60.0 7.9 0.7 404.6 19.5 1.7 319.9 8.2 7.2 3.2 7.6 0.7 348.0 34.4 239.3 16.7 0.7 3.9 109.9 7.4 1.9 50.9 7.2 4.0 161.6 56.9 67.2 3.1 36.5 4.7 10.7 1.6 1.1 314.5 29.7 30.8 10.9 12.7 2570.7 9.1 2584.2 9.3 2337.1 2483.4 9.2 7.8 884.8 1712.5 46.9 553.7 11.3 13.4 4625.7 2238.1 21.3 21.0 20.3 27.6 19.1 20.0 24.0 20.4 23.0 21.2 24.8 21.3 334.4 198.7 64.9 0.0 81.7 59.5 68.0 462.2 12.0 0.4 50.3 44.3 5.6 221.6 119.6 119.5 0.0 9.0 550.3 1038.3 252.4 1696.0 0.2 46.5 36.7 286.4 135.1 64.6 0.1 1490.0 14.1 136.7 118.3 53.7 52.6 1.5 68.6 124.1 4.2 0.0 0.1 273.1 244.1 40.5 116.1 1.9 35.1 60.7 65.8 5.6 225.8 0.0 518.0 0.0 0.1 2546.1 1004.5 45.9 81.7 101.2 4916.6 4315.8 55.1 0.6 19.7 278.5 117.4 5.8 1.3 7.1 51.6 6.6 1711.8 27.8 182.2 105.7 IL4I1 FIG1 ENSG00000104951 "Interleukin 4 induced 1" Q96RQ9 19 49889654-49929539 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 18.3;testis: 26.8" "Group enriched" "Detected in many" 5 "Langerhans cells: 295.1;monocytes: 682.5" "Cancer enhanced" "Detected in all" "ovarian cancer: 35.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 103.4" "Group enriched" "Detected in many" 6 "monocytes: 36.8;T-cells: 103.4" "Cell line enhanced" "Detected in many" "EFO-21: 34.3;HDLM-2: 62.4;Karpas-707: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045598 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cytosol" "HPA045598: AB_10969138" "unprognostic (6.23e-2)" "unprognostic (1.32e-2)" "unprognostic (8.39e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.61e-2)" "unprognostic (3.74e-3)" "unprognostic (7.03e-2)" "unprognostic (2.52e-2)" "unprognostic (3.84e-3)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.23e-10)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" "unprognostic (6.44e-2)" "unprognostic (2.11e-3)" 1.6 0.6 0.4 18.3 0.6 4.2 0.9 0.8 0.6 1.1 0.7 1.7 4.1 1.6 0.2 0.6 3.9 2.0 0.5 0.6 0.5 4.8 1.2 2.4 9.3 1.7 0.9 0.4 0.7 0.2 0.6 1.9 1.8 0.8 1.4 0.1 0.9 0.5 0.3 1.3 2.7 1.5 1.0 4.1 3.1 26.8 1.2 3.4 0.5 0.2 6.7 4.5 0.5 2.3 1.0 1.2 0.8 0.7 0.0 0.8 0.3 0.5 2.0 1.4 2.1 0.7 1.9 3.5 34.3 0.4 2.9 0.5 0.4 0.0 0.2 62.4 0.2 1.6 0.1 0.5 0.1 1.2 12.3 1.0 0.4 0.6 0.1 0.4 2.6 0.4 0.4 47.3 0.1 0.4 0.7 2.1 0.4 0.9 0.1 1.0 0.9 3.6 2.5 3.2 0.7 0.8 0.5 0.9 0.5 0.2 0.4 2.8 2.9 7.1 1.0 0.1 1.0 4.1 9.7 2.0 1.0 0.5 0.7 0.3 22.0 0.3 6.4 36.8 103.4 0.4 13.2 11.5 11.6 0.2 0.3 0.1 0.5 1.3 5.3 1.3 0.7 8.8 0.4 0.6 0.8 0.6 0.6 0.5 1.7 0.9 1.8 1.0 1.2 2.3 0.8 0.0 0.0 0.0 3.6 9.7 0.6 9.8 0.0 0.1 1.2 1.3 0.5 0.0 5.5 3.7 0.0 0.4 1.0 0.2 0.0 3.5 75.4 2.9 0.6 6.7 0.0 0.0 0.4 4.0 0.7 1.3 0.5 2.1 1.3 0.1 1.1 0.2 97.4 0.0 0.4 0.3 6.1 3.0 295.1 18.4 0.3 38.8 3.6 1.9 682.5 0.1 1.0 0.0 0.4 0.5 0.1 0.4 0.7 1.4 0.3 2.7 1.6 0.2 0.0 0.2 2.5 45.2 3.6 0.4 8.2 0.8 6.3 0.0 0.2 2.1 ING2 "ING1L, p33ING2" ENSG00000168556 "Inhibitor of growth family member 2" Q9H160 4 183505058-183512429 "Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019486, HPA021517" Supported Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA019486: AB_1851780, HPA021517: AB_10601914" "prognostic favorable (5.43e-4)" "unprognostic (1.04e-1)" "unprognostic (2.81e-1)" "unprognostic (3.74e-2)" "unprognostic (3.89e-3)" "unprognostic (4.56e-2)" "prognostic unfavorable (8.87e-4)" "unprognostic (7.47e-3)" "unprognostic (2.27e-1)" "unprognostic (1.09e-3)" "unprognostic (1.65e-2)" "unprognostic (1.97e-1)" "unprognostic (2.30e-3)" "unprognostic (6.19e-2)" "unprognostic (4.43e-1)" "unprognostic (5.52e-2)" "unprognostic (7.82e-2)" 9.5 42.3 5.2 5.2 5.8 21.7 8.7 6.8 6.8 7.2 5.5 9.4 10.6 5.2 10.2 14.6 8.8 8.9 7.5 5.0 9.6 12.2 10.5 8.6 5.9 6.4 6.4 37.4 15.8 6.1 23.3 6.1 6.0 8.7 6.7 8.6 10.7 4.5 26.1 12.1 14.3 4.6 4.6 9.1 11.5 33.3 8.0 12.5 9.3 14.8 6.7 11.4 9.9 5.3 19.1 11.4 15.5 12.3 28.1 16.4 12.7 20.1 17.4 15.6 13.3 10.4 20.2 13.5 5.2 14.7 12.7 8.3 10.4 15.6 19.8 10.4 7.6 23.4 11.4 13.5 8.5 19.3 25.1 12.7 14.3 17.0 7.1 12.8 7.5 13.0 13.2 49.8 11.5 18.8 24.7 19.6 12.5 5.5 11.1 10.3 8.6 22.5 18.8 8.7 15.3 11.5 13.3 17.6 5.3 10.0 8.3 13.9 6.4 10.5 16.5 7.2 13.0 10.7 8.6 9.1 19.3 14.3 7.6 15.2 6.3 19.7 3.2 6.6 5.0 11.9 6.3 5.7 7.8 8.4 8.8 7.6 6.4 3.8 8.5 7.6 5.4 3.7 5.2 5.8 6.8 6.8 5.0 9.6 6.4 6.4 6.0 4.6 8.0 5.3 18.7 6.4 21.0 6.2 20.1 49.3 20.5 20.7 105.9 25.7 36.3 41.8 12.1 25.8 18.2 16.5 12.5 26.1 18.8 32.7 74.3 20.9 68.4 93.0 26.3 21.7 18.6 26.7 7.1 34.9 94.9 29.1 11.7 82.9 40.0 85.4 15.4 24.1 30.0 25.2 5.3 24.2 16.2 24.2 43.3 35.2 82.6 27.3 26.6 1.0 13.9 40.5 6.2 3.5 5.1 33.3 28.3 53.8 19.5 34.2 112.9 47.8 39.8 23.6 19.7 23.7 28.0 95.3 74.9 71.6 46.2 21.2 25.6 50.4 23.0 39.3 INPP4A INPP4 ENSG00000040933 "Inositol polyphosphate-4-phosphatase type I A" Q96PE3 2 98444854-98594392 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 150.5;Inhibitory neurons: 124.4;Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 67.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001628 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Nuclear membrane" "HPA001628: AB_10961254" "unprognostic (3.45e-1)" "unprognostic (2.39e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.70e-6)" "unprognostic (1.58e-1)" "unprognostic (3.10e-2)" "unprognostic (1.15e-3)" "unprognostic (9.44e-2)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (9.65e-2)" "unprognostic (3.70e-2)" "unprognostic (2.90e-2)" "unprognostic (4.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (1.97e-2)" 8.7 8.2 15.9 13.2 19.5 12.7 6.1 18.8 22.0 7.0 1.0 11.3 7.3 7.5 5.2 7.7 6.6 9.9 10.5 15.9 9.9 5.2 4.1 9.6 17.2 9.2 3.5 7.0 6.6 8.9 7.7 8.1 9.2 6.0 7.9 10.7 5.6 6.3 8.4 4.1 8.8 9.8 4.7 16.7 7.3 5.9 5.9 20.3 5.9 11.6 12.5 10.8 5.5 10.1 12.7 11.0 18.2 14.8 10.4 11.1 19.2 10.0 9.4 10.9 11.3 14.6 11.5 7.8 13.3 15.4 14.0 12.6 12.6 11.1 8.5 27.7 10.9 9.5 9.7 6.5 8.8 17.3 34.3 9.9 9.9 10.6 9.0 9.5 15.1 44.9 8.5 67.4 8.3 16.2 26.3 16.8 17.6 7.4 11.3 12.0 12.5 51.9 5.6 41.6 12.8 15.7 12.1 10.1 9.5 18.7 4.8 13.8 14.3 12.7 17.9 10.1 7.5 50.2 31.1 5.8 10.5 16.2 11.5 1.1 1.0 2.3 2.8 2.2 3.3 0.4 1.6 1.8 1.1 0.1 2.2 2.5 1.1 3.2 3.4 3.3 0.9 1.0 15.9 19.5 18.8 22.0 15.9 9.9 9.2 3.5 9.2 4.7 5.9 10.1 14.6 6.4 13.1 50.9 11.2 8.0 6.4 2.8 9.1 49.7 5.3 4.2 12.6 2.8 7.8 5.5 8.4 10.2 64.6 4.1 3.9 4.0 13.5 6.2 9.1 14.2 5.4 7.2 150.5 1.5 8.7 9.9 6.6 6.3 0.0 22.4 14.3 3.4 10.5 33.7 124.4 5.6 4.1 36.4 18.4 10.9 9.3 25.3 10.6 73.1 26.8 8.4 71.1 55.8 26.1 3.8 2.5 12.0 48.6 5.9 1.2 3.3 5.1 14.1 6.6 9.9 12.4 8.6 14.0 5.2 6.1 9.4 48.3 9.4 3.6 6.8 INSIG1 "CL-6, MGC1405" ENSG00000186480 "Insulin induced gene 1" O15503 7 155297776-155310235 "Plasma proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 563.4" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 4121.3" "Cancer enriched" "Detected in all" 5 "liver cancer: 142.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "intermediate monocyte: 272.8;non-classical monocyte: 500.8" "Lineage enriched" "Detected in all" 6 "monocytes: 500.8" "Cell line enhanced" "Detected in many" "Karpas-707: 1228.9;RPMI-8226: 605.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071524 Uncertain Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA071524: " "unprognostic (8.11e-2)" "unprognostic (3.22e-1)" "unprognostic (2.91e-1)" "unprognostic (1.47e-1)" "unprognostic (9.23e-2)" "unprognostic (3.83e-2)" "unprognostic (2.05e-2)" "unprognostic (3.06e-1)" "unprognostic (1.60e-2)" "unprognostic (1.52e-1)" "unprognostic (4.64e-2)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.62e-4)" "unprognostic (4.97e-2)" 79.2 37.3 25.3 35.4 36.9 45.5 37.4 47.1 39.1 25.5 58.0 29.8 53.0 19.5 31.8 40.1 17.6 31.6 21.0 30.2 40.9 45.6 563.4 43.2 30.9 61.1 51.7 24.0 111.7 17.4 18.9 34.2 62.8 62.6 26.4 40.5 70.9 11.3 9.0 42.5 35.2 20.3 36.6 19.0 61.1 34.4 36.5 40.4 12.5 12.0 25.3 36.7 23.3 86.3 158.9 29.0 76.8 48.1 200.6 265.5 41.9 12.5 179.1 36.9 242.6 18.1 225.2 104.0 35.7 98.2 282.2 83.9 53.1 92.6 43.3 32.3 155.5 28.6 51.7 0.0 99.0 49.3 448.7 165.6 50.4 281.8 25.8 27.3 49.8 202.8 53.2 1228.9 47.9 82.2 238.7 128.6 80.0 30.4 20.4 43.5 0.2 605.1 291.6 77.8 57.2 45.5 41.6 29.9 67.8 28.7 29.0 162.0 56.3 40.5 11.8 77.2 33.3 296.8 57.4 93.3 177.6 187.2 38.2 21.3 29.7 13.4 49.3 272.8 25.5 46.5 32.8 41.9 78.5 60.2 32.6 36.7 62.6 27.5 500.8 44.7 77.0 85.2 25.3 36.9 47.1 39.1 30.2 40.9 61.1 51.7 62.8 36.6 36.5 86.3 91.4 41.7 121.5 39.8 100.5 140.2 59.4 148.2 74.6 16.5 58.0 31.6 43.6 35.8 114.4 40.5 10.4 47.7 79.0 129.1 17.6 52.0 21.2 30.8 11.6 135.6 126.8 38.3 11.1 140.4 189.0 120.4 57.6 67.4 60.4 18.1 33.2 828.9 46.9 38.7 16.9 91.5 185.1 63.6 4121.3 9.7 15.8 381.0 247.3 7.5 29.6 88.7 34.0 17.1 61.8 53.6 86.6 18.4 100.1 180.4 29.1 9.4 68.3 18.1 19.7 36.3 62.0 33.6 45.0 135.8 155.3 130.4 108.2 20.6 48.0 158.5 INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294414 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 9.8;granulocytes: 5.9;monocytes: 12.5" "Cell line enhanced" "Detected in many" "Karpas-707: 54.9;U-266/70: 40.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" NA Yes 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA036302: AB_2675048, HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" 13.0 22.6 12.5 2.8 16.8 5.6 13.0 17.3 12.8 14.6 18.8 15.0 10.0 18.4 6.3 4.1 16.9 8.2 26.3 10.0 12.2 21.8 33.0 7.2 2.3 18.3 16.3 39.9 64.2 13.0 16.3 7.4 18.7 15.2 10.4 6.5 16.9 9.9 23.5 11.5 12.2 11.5 14.1 48.2 12.5 5.4 16.6 2.7 14.5 13.3 3.5 12.3 9.2 22.5 6.2 3.2 3.6 5.7 18.8 6.1 11.1 3.5 2.9 1.6 1.6 8.4 7.0 9.0 8.2 6.8 4.0 1.6 8.9 1.4 1.2 0.0 6.4 0.0 2.3 22.6 8.2 4.3 6.7 10.0 4.5 0.2 4.9 4.2 3.8 4.8 9.5 54.9 1.8 3.2 3.1 7.8 3.3 3.8 5.2 29.0 2.1 7.6 0.1 27.8 6.6 5.2 6.5 3.8 3.3 6.4 1.4 21.6 3.6 3.4 2.1 8.2 5.1 40.4 23.9 20.2 4.3 7.3 0.0 2.7 8.6 5.9 0.2 8.8 0.3 0.8 0.3 0.1 9.8 1.1 0.7 0.1 1.9 1.0 12.5 8.2 0.0 1.6 12.5 16.8 17.3 12.8 10.0 12.2 18.3 16.3 18.7 14.1 16.6 22.5 75.6 48.1 34.7 64.9 10.6 64.9 63.6 34.7 8.0 40.4 134.0 76.2 92.1 137.2 83.3 62.5 79.2 17.8 6.7 124.1 15.6 55.1 4.7 26.8 106.8 123.9 163.6 25.0 68.3 78.7 53.7 43.7 20.4 42.1 3.8 168.4 255.2 246.0 9.2 38.7 100.8 97.3 32.6 49.0 31.1 9.0 96.3 35.0 51.6 62.8 24.2 31.6 0.0 62.8 183.5 50.7 68.8 245.3 21.8 107.9 122.9 114.1 65.3 23.6 59.2 37.6 44.2 5.2 3.6 3.2 68.8 38.3 4.7 81.4 65.2 130.0 IQCF6 ENSG00000214686 "IQ motif containing F6" A8MYZ5 3 51778561-51779241 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "testis: 21.5" "Group enriched" "Detected in some" 218 "Early spermatids: 379.2;Late spermatids: 188.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 1.0;U-937: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.98e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 21.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 379.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 188.6 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IRF2 ENSG00000168310 "Interferon regulatory factor 2" P14316 4 184387729-184474550 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 163.6;Karpas-707: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030813, CAB032306, HPA057327" Supported Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Cell Junctions, Cytosol" "CAB032306: AB_2249157, HPA030813: AB_10600718, HPA057327: AB_2683410" "prognostic favorable (6.95e-5)" "unprognostic (1.69e-3)" "unprognostic (5.43e-2)" "unprognostic (1.59e-3)" "unprognostic (2.70e-2)" "unprognostic (1.46e-1)" "unprognostic (2.48e-2)" "unprognostic (4.05e-2)" "unprognostic (8.37e-3)" "unprognostic (2.90e-2)" "unprognostic (4.00e-2)" "unprognostic (2.35e-1)" "unprognostic (6.87e-3)" "unprognostic (8.55e-3)" "unprognostic (5.25e-2)" "prognostic favorable (8.34e-5)" "unprognostic (1.31e-3)" 25.1 30.1 18.2 47.8 23.4 18.0 21.9 22.1 19.3 25.6 21.4 27.8 31.1 21.8 22.7 26.7 25.3 24.9 19.5 17.5 21.9 18.5 37.4 27.6 62.5 25.3 22.1 28.1 14.8 20.2 12.3 28.9 25.2 20.6 28.7 9.3 29.1 21.2 28.1 19.4 33.3 23.2 21.7 54.9 31.5 6.1 23.5 49.8 21.7 23.8 52.2 35.6 22.5 29.6 20.3 14.9 17.5 12.0 37.4 37.9 10.5 14.4 44.8 34.8 36.0 4.2 37.9 12.2 7.4 21.7 28.4 18.3 12.0 27.4 22.1 163.6 6.6 34.4 7.9 26.8 37.1 21.1 27.7 41.2 24.8 19.8 50.1 29.8 26.7 14.5 6.9 165.3 14.6 14.1 40.6 25.8 4.0 18.5 10.7 52.7 6.9 55.1 26.6 30.4 7.5 11.6 20.4 16.8 31.3 7.3 13.0 18.9 22.0 9.9 10.7 11.3 12.8 47.3 40.6 11.0 20.9 20.3 17.8 106.7 95.7 175.8 76.4 126.3 77.9 104.9 74.5 82.2 79.6 107.7 78.8 78.8 407.6 94.8 145.7 20.2 111.7 100.3 18.2 23.4 22.1 19.3 17.5 21.9 25.3 22.1 25.2 21.7 23.5 29.6 58.9 38.5 24.5 53.5 68.9 49.1 50.5 60.4 45.5 13.1 25.8 27.3 21.9 27.1 36.0 25.8 6.2 31.3 48.8 40.3 37.2 30.9 0.2 53.4 40.2 42.9 30.6 62.7 23.8 30.1 16.2 35.8 34.1 63.2 26.6 23.1 38.2 37.6 48.5 20.2 27.8 29.5 44.7 90.3 53.5 3.0 37.3 65.9 19.6 41.2 144.0 23.4 70.0 43.7 77.1 28.7 38.9 53.0 63.4 72.9 42.1 46.1 58.7 8.4 39.5 25.4 44.8 0.6 2.4 49.5 44.5 26.7 56.3 37.7 22.8 70.9 IRF2BPL "C14orf4, EAP1, KIAA1865" ENSG00000119669 "Interferon regulatory factor 2 binding protein like" Q9H1B7 14 77024543-77028708 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050862, HPA061333" Approved Enhanced Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA050862: AB_2681258, HPA061333: AB_2684481" "unprognostic (5.58e-2)" "unprognostic (6.48e-2)" "unprognostic (1.99e-3)" "prognostic unfavorable (5.52e-4)" "unprognostic (8.78e-3)" "unprognostic (1.57e-2)" "unprognostic (2.70e-1)" "unprognostic (1.81e-1)" "unprognostic (5.74e-2)" "unprognostic (2.53e-2)" "unprognostic (2.51e-3)" "unprognostic (5.39e-2)" "unprognostic (1.03e-3)" "unprognostic (2.55e-1)" "unprognostic (9.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" 26.1 25.3 12.2 9.2 13.9 5.6 28.5 13.4 12.0 20.1 12.8 32.4 6.9 25.8 5.1 13.3 33.7 6.5 22.6 14.1 21.1 28.7 19.1 20.9 6.2 15.2 14.8 32.4 17.5 19.8 22.6 7.9 10.9 18.4 3.3 7.3 19.2 10.1 16.8 25.2 15.1 8.0 12.6 19.0 18.8 13.5 19.0 9.7 18.7 4.2 3.3 26.4 18.2 9.4 15.4 13.2 32.2 36.3 9.6 8.8 45.8 15.9 13.0 4.4 5.9 6.2 24.8 5.4 11.3 13.6 12.4 23.6 5.6 11.8 3.7 25.8 19.1 6.9 13.0 8.5 12.5 1.9 29.7 11.8 9.1 7.8 6.8 34.8 6.0 10.9 10.4 59.4 5.7 42.2 21.0 14.5 14.5 6.6 68.2 4.4 9.1 13.0 15.6 22.4 24.9 36.0 22.5 23.2 42.5 8.6 16.1 3.4 10.4 20.2 19.5 6.8 10.3 22.9 26.3 9.0 31.3 4.7 25.8 1.7 1.4 1.3 2.8 1.9 2.7 1.4 2.5 2.6 1.3 1.6 2.0 2.3 9.0 5.9 2.3 10.7 2.6 0.8 12.2 13.9 13.4 12.0 14.1 21.1 15.2 14.8 10.9 12.6 19.0 9.4 71.4 22.4 14.3 5.9 40.2 73.7 32.5 22.5 115.5 57.1 54.6 41.5 19.5 32.9 11.6 64.4 29.2 22.8 58.9 10.8 37.2 19.6 1.3 25.3 26.0 44.0 47.6 10.8 8.2 19.0 49.7 47.8 12.2 25.6 26.6 15.2 55.6 60.5 33.3 10.1 8.6 14.7 16.2 54.7 78.9 4.0 30.1 26.6 35.6 9.4 10.0 57.8 38.1 8.5 4.8 17.8 7.0 34.3 21.1 30.0 6.7 23.1 13.8 10.4 39.5 56.4 83.2 1.6 50.5 54.2 50.6 46.0 39.0 27.5 12.8 20.6 IRF4 "LSIRF, MUM1" ENSG00000137265 "Interferon regulatory factor 4" Q15306 6 391752-411443 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.2;cervix: 19.0;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in some" "B-cells: 57.2;dendritic cells: 66.8;Langerhans cells: 109.7;Melanocytes: 44.4;monocytes: 56.1;Plasma cells: 235.6" "Cancer enriched" "Detected in many" 9 "melanoma: 27.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 10.4;myeloid DC: 10.6;naive B-cell: 10.8;plasmacytoid DC: 12.1;T-reg: 5.8" "Group enriched" "Detected in many" 5 "B-cells: 10.8;dendritic cells: 12.1;T-cells: 5.8" "Cell line enhanced" "Detected in some" "HDLM-2: 221.4;Karpas-707: 197.8;RPMI-8226: 200.0;U-266/70: 177.2;U-266/84: 141.3;WM-115: 109.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA002038, HPA002698, CAB013508" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB013508: , HPA002038: AB_1079148, HPA002698: AB_1851893" "prognostic favorable (6.44e-4)" "unprognostic (1.88e-3)" "unprognostic (1.00e-3)" "unprognostic (1.72e-4)" "unprognostic (2.74e-1)" "prognostic favorable (1.64e-6)" "unprognostic (4.72e-2)" "unprognostic (1.05e-1)" "unprognostic (1.89e-2)" "unprognostic (5.74e-4)" "unprognostic (8.51e-2)" "unprognostic (1.12e-1)" "unprognostic (9.18e-7)" "unprognostic (2.38e-1)" "unprognostic (6.24e-2)" "unprognostic (2.90e-1)" "unprognostic (3.65e-2)" 3.1 0.4 0.1 15.9 0.1 29.2 3.2 0.1 0.2 19.0 0.2 6.9 7.6 1.5 0.3 0.9 0.7 2.5 1.0 0.1 0.1 0.4 2.4 2.2 23.2 0.3 0.1 0.6 0.1 0.0 0.3 0.1 0.2 0.5 6.8 0.0 4.5 0.4 0.2 6.8 10.2 0.7 0.2 17.4 7.2 1.1 0.1 7.0 1.1 0.1 26.1 6.3 2.4 0.2 0.4 0.0 0.0 0.0 22.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 221.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 197.8 0.0 0.0 0.1 0.1 1.2 0.0 0.0 26.1 0.0 200.0 0.0 0.0 0.4 0.0 0.0 0.2 32.0 0.6 0.1 0.3 0.0 0.0 0.1 0.0 0.3 177.2 141.3 58.4 0.2 0.0 109.0 0.1 1.8 0.0 0.6 1.5 0.0 10.4 1.0 1.0 10.6 10.8 1.7 0.7 0.0 0.3 1.5 12.1 5.8 1.5 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.2 0.2 0.1 0.2 0.8 0.0 5.3 0.0 57.2 8.3 0.1 0.0 0.0 0.0 0.6 1.5 1.2 1.5 0.0 0.0 0.0 0.0 66.8 0.2 0.0 0.1 0.0 0.3 0.9 0.6 0.0 0.0 0.1 0.7 0.0 1.8 1.5 0.4 0.0 0.0 1.1 0.5 0.3 0.0 0.1 0.1 0.0 0.6 109.7 0.2 3.4 21.7 44.4 0.0 56.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 235.6 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 1.0 0.4 4.3 0.1 29.8 0.0 0.1 0.1 ITGB7 ENSG00000139626 "Integrin subunit beta 7" P26010 12 53191323-53207282 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.0" "Cell type enhanced" "Detected in many" "B-cells: 45.1;dendritic cells: 62.3;NK-cells: 134.9;Plasma cells: 115.9;T-cells: 62.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 99 "Karpas-707: 4821.4;RPMI-8226: 3980.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA042277 Approved "Plasma membrane,Cytosol" NA NA 130000 "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA042277: AB_10793877" "unprognostic (5.34e-2)" "unprognostic (4.47e-2)" "unprognostic (2.80e-3)" "unprognostic (1.40e-2)" "unprognostic (6.57e-4)" "unprognostic (3.51e-5)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (3.58e-1)" "unprognostic (2.18e-1)" "unprognostic (9.63e-3)" "unprognostic (3.36e-1)" "unprognostic (1.02e-2)" "unprognostic (2.16e-1)" "unprognostic (6.95e-2)" "unprognostic (9.34e-2)" "unprognostic (2.47e-4)" 1.6 1.4 1.7 20.0 1.8 15.5 1.9 1.7 2.2 2.7 2.0 9.7 11.7 1.6 2.8 6.4 2.9 3.9 0.8 1.5 2.0 4.7 5.3 6.6 29.2 2.3 1.8 0.7 1.2 0.7 1.3 0.5 2.0 1.7 9.5 1.0 4.1 2.3 0.7 11.9 17.3 2.4 1.9 30.0 8.2 0.6 2.8 8.6 3.1 0.6 26.5 6.2 2.9 2.1 0.1 0.0 0.0 0.3 0.1 0.7 1.4 0.5 0.0 0.0 0.5 0.0 2.1 44.5 0.8 0.0 0.0 9.4 0.0 0.3 0.0 16.5 0.0 1.5 0.0 0.0 0.0 1.0 18.5 1.0 1.8 0.2 0.1 0.6 0.0 2.2 0.4 4821.4 0.0 1.6 0.9 7.0 0.3 41.7 0.1 1.8 0.0 3980.8 0.0 1.2 1.9 0.6 0.1 1.8 0.5 0.0 0.8 10.4 0.0 0.3 0.6 0.9 0.0 8.9 17.9 3.8 3.8 2.6 1.6 80.7 5.6 97.7 52.0 1.4 38.2 28.1 51.8 63.0 44.5 29.8 44.5 44.4 1.5 23.7 0.4 11.9 71.8 17.3 1.7 1.8 1.7 2.2 1.5 2.0 2.3 1.8 2.0 1.9 2.8 2.1 1.0 3.2 5.5 1.3 45.1 2.2 0.3 1.7 3.4 0.1 1.3 1.0 0.5 2.8 1.3 7.3 4.2 0.1 62.3 0.6 7.9 0.3 0.0 1.2 0.4 0.9 0.0 2.1 0.0 0.5 0.1 1.3 2.6 2.4 29.2 0.1 0.4 2.2 13.3 0.0 0.1 0.5 0.0 3.7 10.3 0.3 0.0 17.3 7.2 1.9 13.3 7.0 134.9 0.0 0.5 0.9 1.7 0.0 115.9 0.2 0.0 7.6 0.2 0.8 0.0 1.0 8.2 0.2 1.4 3.3 3.7 0.1 62.5 0.1 1.2 1.4 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.1" "Cell type enhanced" "Detected in many" "B-cells: 27.8;dendritic cells: 20.1;Macrophages: 17.9;NK-cells: 18.6;Plasma cells: 18.4;T-cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 35.7;HEL: 15.9;HMC-1: 15.5;Karpas-707: 40.2;U-266/70: 15.4;U-266/84: 24.7;U-937: 24.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cytosol" "HPA070314: AB_2686251" "unprognostic (5.59e-3)" "prognostic favorable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.7 2.5 4.0 36.3 4.4 18.6 4.0 3.9 5.6 3.3 3.7 4.0 3.0 2.2 2.4 2.8 5.3 4.8 3.2 4.1 6.7 6.2 2.9 13.1 40.5 7.3 6.1 15.5 1.8 1.9 3.1 5.7 6.4 4.4 3.1 0.6 3.5 1.9 0.7 1.7 15.4 3.5 5.5 55.1 4.6 2.6 6.6 11.3 4.9 0.9 29.7 7.4 3.1 6.1 0.2 0.6 0.5 1.8 0.6 2.4 0.4 0.8 0.0 0.1 0.1 0.0 1.6 0.7 3.3 0.7 0.4 0.2 0.0 0.4 0.0 35.7 0.0 15.9 0.1 1.5 1.2 0.0 15.5 8.4 0.5 0.1 0.0 0.1 0.3 3.6 0.1 40.2 0.0 0.7 6.5 0.0 0.3 0.9 1.3 8.2 0.0 0.7 0.8 0.0 0.0 0.6 0.2 0.4 0.1 0.2 3.5 2.4 0.7 0.0 0.7 0.0 0.0 15.4 24.7 4.3 0.1 24.2 0.3 2.0 7.5 0.3 17.8 14.6 20.2 9.4 21.1 18.6 6.8 10.3 20.2 18.5 25.1 13.4 14.2 5.5 18.0 12.4 4.0 4.4 3.9 5.6 4.1 6.7 7.3 6.1 6.4 5.5 6.6 6.1 5.5 0.0 4.6 2.3 27.8 0.8 0.6 0.5 0.6 0.6 0.5 0.8 1.9 0.0 1.0 1.8 0.0 1.1 20.1 0.0 0.0 0.5 1.0 0.3 2.1 8.0 0.0 6.1 4.3 0.4 0.8 4.6 2.0 0.4 5.1 0.8 9.7 0.4 14.5 0.0 2.6 0.0 0.0 9.2 1.9 2.0 12.5 17.9 3.6 4.7 16.6 0.9 18.6 0.0 0.4 0.5 0.0 14.7 18.4 0.5 0.0 0.3 0.9 0.7 6.6 0.3 2.9 0.3 0.7 0.3 1.0 1.4 37.7 14.8 0.1 0.6 JAKMIP2 "JAMIP2, KIAA0555" ENSG00000176049 "Janus kinase and microtubule interacting protein 2" Q96AA8 5 147585438-147782775 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.8" "Group enriched" "Detected in many" 6 "Astrocytes: 195.5;Excitatory neurons: 250.7;Horizontal cells: 85.8;Inhibitory neurons: 229.4;Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 198.5" "Cancer enriched" "Detected in some" 6 "glioma: 4.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 7.3;MAIT T-cell: 5.3;memory CD4 T-cell: 2.8;memory CD8 T-cell: 5.5;naive CD8 T-cell: 4.6;NK-cell: 7.0" "Group enriched" "Detected in many" 6 "NK-cells: 7.0;T-cells: 7.3" "Cell line enhanced" "Detected in many" "AF22: 19.9;Karpas-707: 47.5;RH-30: 47.8;RPMI-8226: 16.0;SCLC-21H: 22.4;SH-SY5Y: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046929, HPA065023" Approved Supported "Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA046929: AB_2679867, HPA065023: AB_2685407" "unprognostic (3.69e-2)" "unprognostic (4.22e-3)" "unprognostic (9.92e-2)" "unprognostic (3.58e-2)" "unprognostic (1.63e-1)" "unprognostic (3.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.71e-2)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.21e-4)" "unprognostic (1.28e-1)" "unprognostic (5.20e-8)" "unprognostic (1.54e-3)" "unprognostic (1.30e-1)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" 0.2 3.3 11.4 1.0 12.5 0.5 0.1 24.8 14.3 0.5 0.1 2.2 0.4 1.0 0.2 1.3 0.1 1.4 0.4 11.4 12.1 0.3 2.6 2.0 0.9 11.7 11.8 0.1 0.8 1.0 8.3 0.1 12.4 0.6 0.5 5.3 0.2 0.4 0.0 0.3 0.6 1.5 10.4 0.8 1.8 2.9 13.0 7.0 0.1 1.6 0.9 0.7 0.2 16.6 0.0 0.0 19.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 8.1 0.0 0.0 4.8 0.1 0.0 0.0 0.0 3.1 6.9 2.0 0.0 0.0 0.3 0.0 5.7 2.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 47.5 0.0 0.1 5.1 0.0 11.4 0.1 0.1 2.0 47.8 16.0 0.0 0.1 22.4 15.4 0.0 0.3 0.1 2.5 0.0 0.0 0.0 3.5 4.0 0.0 1.1 3.3 2.0 4.6 8.9 0.0 0.0 0.0 0.0 0.4 7.3 0.0 5.3 0.7 2.8 5.5 0.1 0.3 0.7 4.6 0.5 7.0 0.2 1.1 1.3 1.5 11.4 12.5 24.8 14.3 11.4 12.1 11.7 11.8 12.4 10.4 13.0 16.6 0.2 0.0 1.5 195.5 1.5 0.0 0.0 0.0 0.0 23.2 0.0 0.1 0.7 0.0 1.3 0.0 2.1 0.0 13.3 0.0 0.0 0.8 11.3 0.2 0.5 0.3 1.2 3.0 250.7 0.0 0.0 1.2 0.5 0.1 29.1 10.3 0.7 3.1 1.3 85.8 229.4 0.8 0.0 0.9 0.0 8.4 0.0 4.2 0.0 11.2 0.4 24.4 23.7 159.3 198.5 0.2 0.0 0.0 3.1 0.0 0.1 0.1 1.5 7.9 0.0 0.4 0.7 7.8 2.0 0.1 0.1 0.3 13.8 18.9 0.0 0.3 JAZF1 "DKFZp761K2222, TIP27, ZNF802" ENSG00000153814 "JAZF zinc finger 1" Q86VZ6 7 27830573-28180795 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Lipid metabolism, Transcription, Transcription regulation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 83.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 160.1;Excitatory neurons: 316.6;Inhibitory neurons: 306.3;Microglial cells: 168.6;Oligodendrocyte precursor cells: 241.3;Oligodendrocytes: 262.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 25.6" "Group enriched" "Detected in all" 4 "dendritic cells: 13.7;granulocytes: 25.6" "Cell line enhanced" "Detected in many" "Karpas-707: 53.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019271, HPA066967" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli fibrillar center" "CAB019271: , HPA066967: AB_2685758" "unprognostic (1.19e-1)" "unprognostic (2.14e-1)" "unprognostic (2.18e-2)" "unprognostic (7.48e-2)" "unprognostic (9.08e-2)" "unprognostic (1.14e-1)" "unprognostic (2.74e-1)" "unprognostic (8.88e-2)" "unprognostic (2.50e-1)" "unprognostic (1.44e-1)" "unprognostic (8.27e-3)" "unprognostic (2.32e-2)" "unprognostic (1.26e-2)" "unprognostic (7.18e-3)" "unprognostic (2.10e-1)" "unprognostic (1.95e-1)" "unprognostic (1.01e-2)" 15.4 83.8 11.1 10.9 12.4 24.4 11.7 11.5 16.5 62.4 12.4 32.8 3.4 41.8 21.3 10.1 16.4 12.4 22.4 13.2 15.3 5.1 15.7 10.1 14.6 7.3 8.3 13.9 6.6 6.3 13.4 16.1 9.1 29.5 8.3 7.8 4.6 35.2 6.9 7.1 8.3 38.6 8.1 14.6 8.3 18.8 17.4 11.5 14.9 6.9 15.9 19.2 27.3 10.0 1.4 0.8 4.8 1.0 35.6 42.9 0.0 11.1 28.6 18.4 22.8 0.1 7.6 33.7 22.6 23.5 12.5 0.7 6.3 8.5 15.0 5.1 10.2 12.2 7.7 0.0 24.2 4.8 3.1 19.4 10.2 13.8 8.9 14.1 11.8 2.2 0.3 53.2 10.3 1.4 1.3 17.5 10.0 0.2 7.7 3.6 2.2 10.1 6.7 0.3 3.0 4.7 9.2 0.3 12.0 14.0 3.5 6.1 11.7 29.0 11.0 8.0 12.9 9.2 2.9 12.5 9.2 12.5 16.2 25.6 3.9 6.9 4.8 3.3 1.3 2.8 1.3 3.2 3.7 3.7 0.5 3.0 1.5 4.1 3.5 13.7 3.2 3.1 11.1 12.4 11.5 16.5 13.2 15.3 7.3 8.3 9.1 8.1 17.4 10.0 10.2 3.2 7.0 57.8 33.4 14.7 3.0 3.8 3.4 6.7 3.5 4.8 25.3 10.0 3.0 1.8 6.2 0.5 37.9 1.3 7.9 14.8 122.1 28.3 160.1 14.5 5.4 115.6 316.6 2.3 1.4 24.6 9.2 18.6 24.1 12.6 3.6 5.5 9.4 16.8 306.3 0.6 2.0 25.7 45.6 89.8 55.0 28.0 23.2 168.6 35.5 4.4 40.2 241.3 262.5 5.3 0.4 34.6 8.7 2.7 0.0 2.4 12.7 4.7 13.1 9.9 15.3 8.7 16.5 3.4 11.2 1.4 25.3 1.6 0.3 1.5 JMY "FLJ37870, WHAMM2" ENSG00000152409 "Junction mediating and regulatory protein, p53 cofactor" Q8N9B5 5 79236131-79327211 "Predicted intracellular proteins" "DNA damage, DNA repair" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 25.2;Karpas-707: 43.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037508, HPA043308" Uncertain Uncertain Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA037508: , HPA043308: AB_10806502" "unprognostic (1.87e-2)" "unprognostic (2.12e-3)" "unprognostic (4.28e-1)" "unprognostic (1.79e-1)" "unprognostic (4.30e-2)" "unprognostic (5.28e-3)" "unprognostic (2.10e-2)" "unprognostic (1.16e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "prognostic favorable (3.03e-5)" "unprognostic (7.21e-2)" "unprognostic (3.22e-1)" "unprognostic (1.85e-1)" "unprognostic (4.15e-1)" 4.5 5.0 5.7 3.4 6.7 10.3 5.8 8.3 7.8 7.3 4.5 10.9 3.2 11.8 7.1 4.9 5.3 4.7 5.0 5.8 5.3 6.4 5.2 4.0 4.2 5.8 5.7 13.3 9.4 11.4 4.8 3.2 6.3 6.4 4.3 11.8 7.4 5.8 8.9 6.7 4.4 7.2 4.9 4.9 5.1 7.3 6.6 5.5 10.2 7.7 4.1 6.0 5.6 7.3 3.8 3.6 2.7 7.1 7.4 6.7 9.5 3.5 9.1 3.2 5.1 1.7 4.1 2.6 25.2 4.0 3.7 4.1 9.6 4.7 5.1 11.5 8.8 5.2 5.9 3.6 11.3 2.3 3.3 6.4 12.3 1.5 13.9 6.6 4.0 6.9 3.2 43.7 2.7 5.0 5.0 4.9 4.5 0.8 2.4 4.9 8.7 11.2 6.9 3.9 10.7 5.8 4.5 4.9 8.3 4.5 4.0 4.8 4.2 1.4 2.4 0.8 2.3 12.3 11.5 2.6 2.8 2.3 2.3 0.0 0.1 0.0 0.3 0.1 0.2 0.2 0.3 0.3 0.0 0.1 0.4 0.3 0.1 0.9 0.0 0.2 0.3 0.0 5.7 6.7 8.3 7.8 5.8 5.3 5.8 5.7 6.3 4.9 6.6 7.3 18.9 9.6 14.9 35.6 36.7 29.8 11.3 11.0 24.5 35.7 14.9 13.7 40.7 15.7 17.4 16.5 43.8 6.4 49.8 6.1 1.9 8.1 35.6 36.3 35.2 16.7 23.9 18.7 55.5 9.8 5.4 24.6 15.8 53.9 8.2 28.8 8.6 15.4 4.4 40.4 53.6 8.3 10.2 9.3 21.0 21.5 24.2 35.8 23.2 15.9 5.2 20.5 9.2 47.7 42.5 10.7 7.6 35.7 85.2 21.4 6.8 7.8 24.9 40.8 13.1 29.6 27.7 37.1 39.2 19.8 39.8 20.2 56.5 34.6 7.6 17.6 KCNA2 "HK4, Kv1.2" ENSG00000177301 "Potassium voltage-gated channel subfamily A member 2" P16389 1 110519837-110631474 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 81.3" "Group enriched" "Detected in some" 4 "Astrocytes: 49.9;Excitatory neurons: 36.7;Inhibitory neurons: 37.1;Muller glia cells: 19.8;Oligodendrocyte precursor cells: 36.2" "Cancer enhanced" "Detected in some" "glioma: 1.2;testis cancer: 1.0" "Region enhanced" "Detected in many" "cerebral cortex: 81.3" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Lineage enriched" "Detected in single" 8 "T-cells: 1.3" "Cell line enhanced" "Detected in some" "Karpas-707: 4.8;SCLC-21H: 1.4;U-2 OS: 1.2;U-266/70: 1.9;U-266/84: 3.1;WM-115: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001976 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB001976: " "unprognostic (1.84e-2)" "unprognostic (9.70e-3)" "unprognostic (1.97e-1)" "unprognostic (2.98e-1)" "unprognostic (7.17e-3)" "unprognostic (6.68e-3)" "unprognostic (5.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.29e-1)" "unprognostic (4.50e-3)" "unprognostic (3.08e-3)" "unprognostic (2.93e-4)" "unprognostic (2.15e-1)" "unprognostic (3.55e-1)" "unprognostic (6.41e-2)" "unprognostic (2.83e-1)" 1.3 0.3 5.0 0.7 7.4 0.0 0.6 11.1 81.3 0.2 0.0 1.6 0.4 0.1 0.3 0.4 0.1 0.3 0.7 4.5 12.5 0.1 0.0 0.1 0.6 28.0 7.5 0.1 0.8 0.0 2.1 0.0 32.0 0.5 0.5 9.6 0.5 0.8 1.0 0.5 0.6 0.4 0.1 0.3 0.7 0.9 27.1 3.0 2.3 2.1 1.5 0.3 0.3 20.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.7 0.0 0.0 1.4 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.9 3.1 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 5.0 7.4 11.1 81.3 4.5 12.5 28.0 7.5 32.0 0.1 27.1 20.7 0.1 0.0 0.0 49.9 0.2 0.0 0.0 0.0 0.0 7.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.5 0.2 0.0 0.0 36.7 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 37.1 0.0 0.0 0.0 0.0 1.1 0.0 0.9 0.0 8.4 0.0 19.8 0.0 36.2 6.8 0.0 0.0 5.3 1.6 0.0 0.0 0.0 0.0 4.2 0.0 0.4 1.0 0.0 2.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 KCNA3 "HLK3, HPCN3, Kv1.3, MK3" ENSG00000177272 "Potassium voltage-gated channel subfamily A member 3" P22001 1 110672465-110674940 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 25.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 13.1;Inhibitory neurons: 60.2;Plasma cells: 61.6;T-cells: 20.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 4.9;T-cells: 14.3" "Cell line enhanced" "Detected in some" "HDLM-2: 23.1;Karpas-707: 45.6;U-266/70: 32.6;U-266/84: 31.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016625 Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "HPA016625: AB_2669407" "unprognostic (2.17e-2)" "unprognostic (5.07e-3)" "unprognostic (3.92e-3)" "unprognostic (1.20e-2)" "unprognostic (2.35e-1)" "unprognostic (1.76e-5)" "unprognostic (1.70e-4)" "unprognostic (8.48e-2)" "unprognostic (1.49e-2)" "unprognostic (5.92e-4)" "unprognostic (1.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.13e-2)" "unprognostic (2.99e-2)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" 0.5 0.9 3.4 6.4 2.0 4.6 0.9 1.1 4.9 1.1 0.0 2.4 2.5 0.5 0.0 0.5 0.3 1.3 0.4 5.0 7.2 0.2 0.8 5.9 9.4 1.1 3.3 0.7 0.4 0.4 0.4 0.7 5.0 0.5 1.9 0.6 1.4 0.2 0.1 0.2 2.6 0.6 0.2 6.0 4.3 0.5 3.3 25.4 0.7 0.1 7.6 2.6 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 45.6 0.0 0.0 10.0 0.0 0.9 0.0 0.0 0.0 0.0 9.6 0.0 0.0 6.3 0.5 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.7 0.0 0.0 32.6 31.9 11.6 0.0 2.7 0.0 0.0 1.1 0.0 8.9 0.0 10.0 2.8 13.4 14.3 1.4 4.9 10.4 7.9 0.0 1.3 0.1 0.6 13.4 4.4 3.4 2.0 1.1 4.9 5.0 7.2 1.1 3.3 5.0 0.2 3.3 0.0 0.2 0.0 1.9 1.3 11.5 0.4 0.0 0.0 0.0 2.5 0.1 0.0 0.6 0.0 0.0 1.8 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.3 13.1 0.0 0.0 0.7 1.5 0.0 0.0 0.0 1.8 0.0 0.4 0.0 60.2 0.0 0.0 1.6 2.4 0.0 0.0 3.1 3.6 2.8 2.4 0.3 3.1 7.5 1.3 0.0 0.0 0.0 61.6 0.0 0.0 0.1 0.0 0.2 6.6 0.0 0.1 4.3 0.9 0.1 0.6 0.0 20.3 0.0 0.0 0.1 KCTD20 "C6orf69, dJ108K11.3, MGC14254" ENSG00000112078 "Potassium channel tetramerization domain containing 20" Q7Z5Y7 6 36442767-36491143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 126.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030092 Approved Approved "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "Nuclear speckles" "HPA030092: AB_10601437" "unprognostic (2.17e-1)" "unprognostic (2.02e-1)" "unprognostic (5.20e-3)" "unprognostic (2.43e-2)" "unprognostic (1.00e-3)" "unprognostic (5.03e-3)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.63e-1)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.22e-1)" "unprognostic (8.05e-2)" "prognostic unfavorable (8.02e-4)" "unprognostic (1.18e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (9.31e-4)" "unprognostic (2.94e-2)" 41.6 25.9 15.3 28.1 16.7 27.7 21.3 16.0 16.4 23.7 14.8 21.5 14.3 25.7 15.4 28.1 19.5 28.9 18.0 15.6 19.5 16.0 31.2 22.0 27.6 18.6 19.4 22.8 12.8 14.6 11.9 26.0 18.6 19.3 18.1 10.9 14.6 21.0 20.7 29.6 15.7 31.5 16.3 25.3 14.7 10.3 17.0 34.8 14.3 18.9 29.5 28.6 17.6 17.5 36.7 16.9 47.0 90.4 62.8 41.3 23.4 43.7 60.4 46.9 52.2 43.6 20.8 124.3 38.2 72.4 26.8 33.3 62.3 31.4 77.3 90.3 34.9 70.3 26.0 46.5 29.9 68.9 46.8 41.1 32.5 36.1 23.0 31.2 48.7 64.1 112.8 68.2 44.9 33.1 78.5 26.6 17.5 29.1 15.3 78.0 53.4 68.8 25.5 40.6 11.4 65.9 38.4 38.6 116.6 46.6 53.5 68.1 56.4 126.2 43.4 37.5 55.0 53.0 132.9 87.8 21.7 93.7 131.4 29.7 17.4 11.4 8.1 15.1 9.4 6.8 6.5 6.8 16.3 5.6 6.5 6.6 12.5 7.8 8.9 9.0 8.6 13.9 15.3 16.7 16.0 16.4 15.6 19.5 18.6 19.4 18.6 16.3 17.0 17.5 38.3 38.5 23.7 21.9 28.6 50.1 19.6 15.2 24.5 22.4 23.7 23.9 15.9 28.6 22.2 16.5 10.4 26.3 45.4 14.0 1.9 18.2 0.7 20.0 33.8 38.3 15.1 64.6 23.3 14.2 18.9 38.9 23.9 24.6 53.8 40.8 44.6 45.6 26.7 15.2 23.3 15.5 12.2 51.3 126.3 2.3 31.7 61.4 33.8 27.2 58.4 18.1 30.9 22.6 26.5 19.5 16.3 53.4 48.7 18.9 18.8 19.0 22.5 10.5 19.7 35.8 42.7 8.1 27.2 27.6 63.4 23.0 39.6 23.8 16.1 32.2 KLHL2 MAV ENSG00000109466 "Kelch like family member 2" O95198 4 165207561-165323156 "Predicted intracellular proteins" "Ubl conjugation pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 78.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 125.4;Oligodendrocytes: 144.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051637 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Vesicles "HPA051637: " "unprognostic (1.14e-1)" "unprognostic (8.11e-2)" "unprognostic (1.46e-1)" "unprognostic (8.31e-3)" "unprognostic (1.46e-1)" "unprognostic (1.56e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-3)" "unprognostic (4.42e-2)" "unprognostic (2.06e-1)" "unprognostic (4.67e-1)" "unprognostic (4.88e-2)" "prognostic favorable (3.77e-4)" "unprognostic (4.21e-2)" "unprognostic (1.83e-1)" "unprognostic (2.30e-2)" "unprognostic (1.81e-1)" 11.8 11.8 35.3 12.1 50.9 21.4 13.0 26.7 55.8 5.9 14.3 7.2 5.3 7.7 13.5 19.7 9.9 10.7 5.5 78.4 34.7 15.4 27.1 14.2 11.2 33.2 35.7 4.1 7.8 9.5 16.3 7.7 30.8 8.2 6.7 8.8 20.0 10.0 4.7 6.4 6.5 10.7 33.3 14.6 8.3 6.1 35.5 6.3 12.3 6.8 9.5 15.2 8.8 45.2 16.1 14.7 9.8 10.1 14.1 12.9 10.2 21.3 16.7 10.7 11.7 8.9 11.5 16.3 5.1 10.9 19.2 10.5 16.1 10.4 13.9 27.2 6.0 14.1 12.8 12.9 12.9 14.2 19.3 10.7 30.5 9.8 37.1 18.5 25.9 6.1 6.4 33.0 16.1 6.0 0.4 4.0 6.0 8.9 6.5 5.6 7.0 5.1 18.1 14.9 49.1 8.1 13.5 4.5 13.0 18.1 3.3 15.1 37.0 8.4 17.6 9.6 14.0 21.5 16.3 13.2 10.1 9.7 16.9 1.8 0.9 1.3 0.5 1.0 0.3 0.3 0.3 0.3 0.8 0.8 0.9 1.0 7.2 0.3 1.2 0.4 0.5 0.4 35.3 50.9 26.7 55.8 78.4 34.7 33.2 35.7 30.8 33.3 35.5 45.2 19.0 6.4 17.9 33.3 10.7 6.0 13.1 8.0 4.6 8.9 13.2 10.9 4.7 8.6 9.7 22.0 14.6 4.3 8.3 7.5 27.4 8.7 1.9 8.3 6.6 14.6 15.5 2.1 125.4 12.9 9.4 5.2 8.2 13.5 9.5 4.0 25.7 35.6 8.3 32.0 33.0 6.2 8.2 42.5 13.9 1.7 4.1 22.7 5.4 39.4 13.5 5.8 1.0 43.2 144.5 9.6 7.4 4.5 6.3 11.9 5.4 19.0 10.9 7.3 0.0 11.9 7.2 3.3 7.4 7.7 7.5 3.7 9.2 3.9 3.9 20.1 KLHL28 "BTBD5, FLJ20081" ENSG00000179454 "Kelch like family member 28" Q9NXS3 14 44924324-45042322 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 27.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000988 Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA000988: AB_1845480" "unprognostic (8.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (7.84e-3)" "unprognostic (9.20e-2)" "unprognostic (4.36e-3)" "unprognostic (4.92e-2)" "unprognostic (2.66e-1)" "unprognostic (2.14e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (4.68e-2)" "unprognostic (7.55e-2)" "unprognostic (4.34e-1)" "unprognostic (1.75e-2)" "unprognostic (6.53e-2)" 4.6 4.8 2.6 6.5 3.4 27.0 5.7 9.0 3.6 5.2 3.3 5.0 5.1 5.3 5.0 6.5 5.4 5.5 4.1 2.9 3.9 4.6 6.4 5.6 8.7 3.2 2.9 7.8 3.8 4.2 3.0 5.6 3.5 5.5 6.0 8.1 4.3 3.9 4.7 5.1 5.0 5.8 3.3 5.8 5.0 7.3 3.3 9.2 7.6 8.0 7.4 5.6 3.5 6.4 4.5 6.7 8.6 5.6 7.7 6.8 6.5 5.8 6.4 8.4 7.1 3.0 6.8 6.6 6.2 10.1 2.2 7.6 7.7 6.1 9.2 12.3 4.2 5.7 6.9 3.4 6.9 9.2 12.0 5.3 8.6 5.4 8.6 4.8 6.8 10.2 5.1 16.0 4.9 6.5 7.4 4.7 5.3 5.0 6.3 6.3 9.6 3.7 4.8 8.0 9.8 6.0 7.5 5.0 8.1 5.5 9.4 3.9 8.7 7.5 8.6 5.3 3.3 9.4 11.0 9.2 2.6 4.1 4.6 31.5 7.3 18.3 17.0 10.2 31.5 14.9 17.0 18.0 6.4 13.0 20.0 17.2 16.8 20.3 11.2 8.7 14.2 6.9 2.6 3.4 9.0 3.6 2.9 3.9 3.2 2.9 3.5 3.3 3.3 6.4 15.7 16.0 9.4 17.0 30.1 24.5 16.4 20.1 27.9 24.8 12.9 10.4 12.1 11.5 17.6 18.4 35.5 7.7 27.5 14.9 7.9 10.0 40.2 20.0 13.6 15.4 13.9 27.8 32.6 5.6 8.3 18.0 17.3 9.7 19.0 10.2 16.8 13.1 9.2 15.2 30.0 12.1 6.1 15.8 23.6 62.8 21.8 19.1 23.2 16.9 15.7 23.2 23.7 36.7 40.4 10.3 12.7 17.7 27.0 12.6 13.1 8.5 32.3 23.4 13.1 14.6 19.8 10.8 5.1 19.4 30.1 14.1 38.6 7.7 9.5 15.8 KRT36 KRTHA6 ENSG00000126337 "Keratin 36" O76013 17 41486136-41492546 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 3.5;skin 1: 1.7" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 1.8;Late spermatids: 2.1;Prostatic glandular cells: 1.0;Spermatogonia: 2.4;Squamous epithelial cells: 2.0" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "Karpas-707: 3.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA 180000000 "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (4.39e-2)" "unprognostic (2.24e-3)" "unprognostic (9.85e-2)" "unprognostic (4.66e-1)" "unprognostic (1.70e-2)" "unprognostic (3.19e-2)" "unprognostic (1.34e-1)" "unprognostic (5.36e-2)" "unprognostic (2.25e-1)" "unprognostic (1.81e-1)" "unprognostic (7.19e-2)" "unprognostic (8.24e-2)" "unprognostic (8.50e-2)" "unprognostic (3.74e-1)" "unprognostic (6.66e-2)" "unprognostic (1.49e-1)" "unprognostic (7.11e-2)" 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.7 0.1 0.0 0.0 0.4 0.0 0.2 0.1 3.5 0.0 0.0 1.7 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.3 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.3 0.1 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.8 0.0 2.1 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.4 2.0 0.0 0.0 0.0 0.1 0.2 0.9 LAMP5 "BAD-LAMP, C20orf103, dJ1119D9.3, UNC-46" ENSG00000125869 "Lysosomal associated membrane protein family member 5" Q9UJQ1 20 9514358-9530524 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 96.6;retina: 29.6" "Cell type enhanced" "Detected in many" "dendritic cells: 78.4;Granulosa cells: 22.2;Horizontal cells: 60.6;Inhibitory neurons: 38.9;Theca cells: 23.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "plasmacytoid DC: 141.3" "Lineage enriched" "Detected in many" 31 "dendritic cells: 141.3" "Cell line enhanced" "Detected in some" "Karpas-707: 469.4;SH-SY5Y: 86.4;THP-1: 169.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004802, HPA070765" Enhanced Uncertain "Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Mitotic spindle, Centriolar satellite" "HPA004802: AB_10603682, HPA070765: AB_2686309" "unprognostic (2.78e-2)" "unprognostic (3.90e-3)" "unprognostic (5.73e-4)" "unprognostic (5.47e-2)" "unprognostic (7.89e-2)" "unprognostic (2.67e-1)" "unprognostic (3.80e-3)" "unprognostic (1.45e-1)" "unprognostic (1.54e-2)" "unprognostic (1.91e-1)" "unprognostic (1.94e-1)" "unprognostic (1.95e-1)" "prognostic unfavorable (6.46e-6)" "unprognostic (5.12e-3)" "unprognostic (3.74e-2)" "unprognostic (1.08e-2)" "unprognostic (4.49e-3)" 0.5 4.3 41.7 1.5 96.6 2.3 0.9 11.0 51.8 8.8 3.7 2.2 1.2 4.8 6.3 0.4 10.6 3.1 0.4 39.1 14.3 0.8 0.2 0.9 5.7 47.7 10.1 21.9 1.2 0.7 6.3 0.1 43.7 2.3 1.2 29.6 1.1 3.8 0.1 0.7 1.3 3.9 29.1 1.8 1.4 0.9 35.3 1.4 0.9 0.2 5.2 0.7 1.2 13.6 0.1 0.2 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 469.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 86.4 0.0 0.0 0.1 0.4 0.0 169.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 21.1 0.3 4.2 1.7 0.0 0.0 0.3 0.2 4.5 0.0 0.1 9.5 0.5 0.0 0.0 0.4 0.0 0.0 141.3 0.0 2.4 41.7 96.6 11.0 51.8 39.1 14.3 47.7 10.1 43.7 29.1 35.3 13.6 0.5 0.0 1.1 6.2 3.4 0.1 0.0 0.0 0.0 12.3 0.3 4.3 0.3 0.0 0.0 0.0 8.4 0.0 78.4 0.0 0.0 0.8 5.4 0.2 0.7 0.8 0.0 0.0 10.0 0.0 0.0 8.4 0.0 0.7 0.0 22.2 0.0 0.0 1.3 60.6 38.9 0.0 0.0 0.6 0.8 7.5 0.6 3.5 3.6 4.7 5.4 3.9 0.0 13.0 1.5 0.4 0.0 0.0 5.5 0.5 0.0 0.0 0.0 5.7 0.0 0.3 13.9 0.6 1.1 0.0 0.0 0.0 0.9 23.2 0.1 0.0 LDLRAP1 "ARH, ARH2, DKFZp586D0624, FHCB1, FHCB2, MGC34705" ENSG00000157978 "Low density lipoprotein receptor adaptor protein 1" Q5SW96 1 25543606-25568886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Atherosclerosis, Disease variant, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "NK-cells: 39.5;T-cells: 107.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003705, HPA050358" Uncertain Approved Microtubules NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Microtubules "CAB003705: AB_425923, HPA050358: AB_2681103" "unprognostic (2.52e-2)" "unprognostic (5.39e-3)" "unprognostic (7.49e-3)" "unprognostic (4.12e-2)" "unprognostic (1.40e-1)" "unprognostic (1.18e-2)" "unprognostic (1.70e-2)" "unprognostic (7.27e-3)" "unprognostic (4.79e-1)" "unprognostic (1.18e-1)" "unprognostic (1.20e-3)" "unprognostic (9.96e-2)" "unprognostic (6.49e-2)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (2.74e-2)" "unprognostic (4.24e-1)" 11.0 19.7 14.2 18.8 25.0 8.6 11.7 28.4 17.7 11.3 25.5 18.2 11.3 8.8 8.0 19.4 9.8 8.0 12.6 14.4 17.5 14.4 27.2 15.7 37.2 30.6 25.0 9.3 39.6 14.7 19.4 21.1 27.6 21.5 16.4 5.5 30.9 9.8 13.1 21.2 16.8 10.4 21.4 58.1 15.8 5.6 22.7 14.2 17.2 9.3 22.0 9.7 15.4 37.9 32.2 12.5 17.5 18.5 10.7 12.3 14.1 20.0 19.5 30.0 20.8 5.1 26.0 7.1 14.2 27.4 20.9 33.3 11.9 20.3 15.1 8.5 18.5 11.4 14.5 9.8 17.0 13.1 16.4 13.4 28.6 24.2 9.0 7.3 26.1 7.1 16.0 68.1 10.0 18.6 0.2 22.4 22.2 25.7 13.2 1.9 19.7 57.6 11.2 6.6 8.7 4.9 27.8 43.9 32.3 14.1 20.0 22.2 15.7 13.1 19.1 25.0 14.1 64.8 81.6 20.2 44.2 10.9 16.3 0.0 7.0 0.3 23.6 5.7 27.1 10.5 55.2 43.4 9.4 5.4 107.3 89.8 3.1 39.5 5.9 1.3 49.7 50.6 14.2 25.0 28.4 17.7 14.4 17.5 30.6 25.0 27.6 21.4 22.7 37.9 9.8 0.0 11.0 2.6 11.5 8.3 20.6 21.5 15.4 4.0 10.3 13.3 3.6 5.7 21.1 7.3 18.8 35.2 13.3 33.6 3.9 9.7 0.2 2.9 4.1 10.8 6.7 3.8 2.3 17.8 8.6 8.9 4.6 5.4 2.5 8.6 12.1 25.6 11.0 70.7 1.2 23.9 10.2 6.0 3.5 0.0 10.2 23.7 17.8 11.2 6.9 4.0 22.6 2.0 50.1 12.9 23.4 8.6 19.3 19.1 11.9 5.9 6.1 19.5 26.3 16.9 9.1 3.2 10.1 12.4 5.7 23.7 28.7 9.7 22.0 20.0 LILRB4 "CD85k, HM18, ILT3, LIR-5, LIR5" ENSG00000186818 "Leukocyte immunoglobulin like receptor B4" Q8NHJ6 19 54643889-54670359 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.7;lymphoid tissue: 18.8" "Cell type enhanced" "Detected in some" "dendritic cells: 76.9;Hofbauer cells: 127.6;Kupffer cells: 118.9;Macrophages: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 37.3" "Group enriched" "Detected in many" 44 "dendritic cells: 37.3;monocytes: 10.8" "Cell line enriched" "Detected in some" 32 "Karpas-707: 407.8" HPA052807 Approved NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052807: AB_2681958" "unprognostic (4.09e-2)" "unprognostic (5.75e-3)" "unprognostic (6.06e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.03e-2)" "unprognostic (3.53e-1)" "unprognostic (4.13e-2)" "unprognostic (1.52e-1)" "unprognostic (5.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.91e-2)" "unprognostic (1.08e-1)" "unprognostic (4.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.52e-2)" 8.6 4.6 2.2 10.9 2.5 2.0 3.6 2.7 4.2 1.1 2.2 4.1 1.6 0.9 0.3 1.0 4.0 1.7 2.3 2.2 2.8 2.2 2.9 13.7 11.4 3.8 3.2 0.7 1.6 0.1 2.2 1.4 3.5 1.9 2.3 0.1 3.6 0.3 0.5 0.5 6.3 0.7 3.2 18.8 1.7 0.3 3.0 0.6 2.4 0.0 2.1 6.1 0.8 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 407.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.4 12.8 0.0 0.2 0.0 0.4 0.0 7.8 0.0 0.0 10.8 0.0 0.2 0.0 0.0 11.7 0.5 0.0 0.0 0.1 0.1 8.9 37.3 0.0 3.8 2.2 2.5 2.7 4.2 2.2 2.8 3.8 3.2 3.5 3.2 3.0 3.3 0.6 0.0 4.1 0.0 13.4 0.4 0.0 0.0 0.0 0.2 0.3 1.7 1.0 1.5 1.3 0.0 0.0 0.3 76.9 0.1 0.0 0.0 0.2 0.0 0.0 4.2 0.0 7.8 0.1 0.0 0.9 0.5 0.0 0.0 1.3 0.0 2.2 0.8 127.6 0.0 0.2 0.0 0.0 118.9 12.6 0.6 0.0 104.0 1.8 14.0 29.3 0.2 1.0 0.0 0.0 0.1 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.2 6.6 0.2 0.1 0.0 0.4 0.1 0.1 0.8 2.2 0.0 0.2 0.1 LONRF1 "FLJ23749, RNF191" ENSG00000154359 "LON peptidase N-terminal domain and ring finger 1" Q17RB8 8 12721906-12756073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023584, HPA024814" Uncertain Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Centrosome "HPA023584: AB_1853233, HPA024814: AB_1853235" "unprognostic (2.59e-1)" "unprognostic (2.17e-3)" "unprognostic (1.35e-2)" "unprognostic (3.56e-1)" "unprognostic (9.09e-2)" "unprognostic (3.96e-3)" "unprognostic (3.13e-1)" "unprognostic (5.78e-2)" "unprognostic (2.74e-3)" "unprognostic (1.18e-1)" "unprognostic (5.83e-2)" "unprognostic (3.39e-1)" "unprognostic (5.46e-3)" "unprognostic (8.97e-2)" "unprognostic (8.90e-2)" "unprognostic (3.08e-3)" "unprognostic (1.15e-1)" 16.2 5.8 2.8 4.5 2.7 5.9 10.5 3.4 3.7 11.4 1.3 7.7 2.3 11.3 9.6 13.0 10.5 9.5 4.9 3.0 2.3 6.3 9.9 7.3 7.1 2.2 2.1 15.2 7.5 8.0 3.8 10.1 1.9 10.7 4.3 7.9 8.0 10.6 17.2 28.7 4.5 9.2 2.3 8.4 5.4 15.8 2.6 6.8 8.7 11.3 8.1 7.9 8.3 3.0 1.2 3.0 15.0 4.6 15.6 7.4 10.0 3.8 6.3 4.1 5.7 0.9 3.9 24.0 0.9 6.7 12.9 1.8 12.0 4.7 4.6 3.7 6.8 7.9 0.5 6.2 14.4 2.1 3.0 7.0 8.2 2.6 8.9 3.8 6.4 9.7 1.1 56.6 2.7 4.2 10.4 7.0 15.5 4.8 0.9 5.8 10.2 4.3 3.5 10.2 31.2 3.6 2.2 5.1 29.8 10.7 1.0 10.4 2.9 2.2 3.7 8.9 3.0 4.3 20.7 12.4 12.0 7.2 7.0 0.0 0.1 0.6 0.1 0.5 0.3 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 2.8 2.7 3.4 3.7 3.0 2.3 2.2 2.1 1.9 2.3 2.6 3.0 18.9 9.6 16.3 23.2 25.2 60.8 32.8 7.8 52.3 25.1 15.1 10.3 9.7 10.0 13.1 11.0 16.7 3.6 6.3 4.3 7.9 5.3 57.4 12.1 27.9 15.1 2.4 4.6 67.0 4.0 8.2 24.2 5.6 28.3 6.3 27.8 6.1 14.7 5.6 8.4 43.6 6.4 4.1 9.5 27.6 53.5 29.2 17.2 44.4 21.5 3.6 8.3 0.0 42.7 14.9 4.3 6.4 19.9 16.3 26.4 3.8 6.0 8.7 13.0 19.7 36.7 32.7 8.2 19.7 26.4 73.6 7.3 9.7 3.4 5.8 30.1 LRIF1 "C1orf103, FLJ11269, RIF1" ENSG00000121931 "Ligand dependent nuclear receptor interacting factor 1" Q5T3J3 1 110947190-110963965 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044515 Uncertain Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "Centriolar satellite" "HPA044515: AB_10796800" "unprognostic (5.06e-2)" "unprognostic (4.82e-2)" "unprognostic (4.74e-1)" "unprognostic (3.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.72e-1)" "unprognostic (1.27e-3)" "unprognostic (1.85e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.73e-4)" "unprognostic (5.14e-2)" "unprognostic (9.23e-3)" "unprognostic (3.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.48e-1)" "unprognostic (3.88e-2)" "unprognostic (2.70e-1)" 6.6 9.4 8.7 10.3 9.1 5.5 11.4 10.7 18.5 6.2 8.5 6.5 6.0 6.8 19.8 5.6 8.1 5.0 14.5 9.2 10.3 7.9 13.2 6.8 16.0 8.4 8.7 15.5 6.1 6.5 7.7 10.0 8.7 8.2 6.4 21.5 7.2 5.4 18.2 9.3 6.0 4.7 8.7 13.0 7.1 25.7 9.5 13.3 10.9 17.3 17.4 7.6 4.5 10.0 33.2 14.4 26.8 18.4 12.3 19.8 30.2 19.9 22.7 33.8 27.2 36.4 40.4 25.2 27.5 15.1 36.5 21.0 12.9 12.0 40.6 45.9 15.2 27.9 14.3 37.4 35.8 52.7 32.5 12.5 32.3 23.5 41.0 14.4 18.6 26.4 88.3 111.5 23.2 11.1 5.4 41.4 40.0 20.1 32.6 35.0 43.4 30.5 8.8 17.0 22.3 24.4 0.1 33.8 59.1 16.3 28.0 83.6 13.5 30.0 1.0 35.4 16.3 51.7 19.4 46.9 17.1 59.2 53.6 24.8 8.3 18.6 21.0 9.4 26.6 29.9 16.6 22.1 16.8 22.7 18.1 24.8 31.4 28.2 13.0 15.0 16.9 12.8 8.7 9.1 10.7 18.5 9.2 10.3 8.4 8.7 8.7 8.7 9.5 10.0 22.5 12.8 8.4 11.8 39.4 14.4 48.4 21.0 19.9 22.4 27.9 35.1 27.8 8.6 17.0 9.2 18.8 19.5 21.9 15.5 15.6 18.8 15.3 15.9 15.2 21.5 11.3 24.8 17.9 19.9 32.3 16.5 23.0 18.5 8.2 11.2 17.5 31.8 13.9 15.2 16.5 13.2 18.3 10.7 53.1 11.4 15.8 23.2 32.0 3.7 20.1 28.6 49.4 4.0 16.1 23.4 12.9 13.9 28.4 56.8 10.0 11.8 22.3 35.1 13.1 20.0 19.0 49.9 54.8 25.1 17.6 37.8 31.5 21.4 11.3 50.9 LRRTM4 FLJ12568 ENSG00000176204 "Leucine rich repeat transmembrane neuronal 4" Q86VH4 2 76747685-77593319 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 17.6;retina: 6.8" "Group enriched" "Detected in some" 16 "Excitatory neurons: 3972.6;Inhibitory neurons: 2310.6;Oligodendrocyte precursor cells: 3758.4" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 10 "Karpas-707: 125.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.00e-1)" "unprognostic (4.40e-2)" "unprognostic (3.13e-1)" "unprognostic (4.72e-4)" "unprognostic (7.20e-2)" "unprognostic (1.30e-1)" "unprognostic (1.27e-2)" "unprognostic (9.15e-2)" "unprognostic (3.93e-1)" "unprognostic (5.84e-2)" "unprognostic (4.22e-2)" "unprognostic (1.40e-1)" "unprognostic (2.64e-1)" "unprognostic (5.77e-3)" "unprognostic (3.54e-2)" "unprognostic (7.99e-2)" 0.4 0.6 5.8 0.3 11.4 1.7 0.2 0.1 17.6 0.4 0.0 0.5 0.8 0.4 1.5 0.8 0.2 0.7 0.1 13.5 1.6 0.2 1.3 0.8 0.4 0.2 4.1 0.6 0.5 0.0 1.0 0.9 1.2 0.6 0.5 6.8 0.9 1.5 1.6 0.8 0.5 0.3 0.0 0.5 0.6 0.3 0.0 0.1 0.7 0.3 0.2 0.3 0.5 14.5 1.4 1.7 0.9 0.8 0.0 0.0 0.9 0.3 0.0 0.0 0.0 2.1 0.5 1.0 2.2 0.8 0.7 0.8 0.2 0.0 0.3 0.8 2.5 0.5 4.8 3.1 0.4 1.3 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.5 125.8 0.0 2.8 0.5 0.7 12.2 0.2 1.2 0.5 0.1 2.6 0.0 4.1 3.7 1.4 0.8 0.7 0.8 2.0 1.4 0.9 0.0 2.9 3.7 0.1 0.2 0.0 2.4 0.1 2.8 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.5 0.2 0.1 0.0 0.1 0.0 5.8 11.4 0.1 17.6 13.5 1.6 0.2 4.1 1.2 0.0 0.0 14.5 0.0 0.0 0.5 208.6 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.3 0.3 0.0 0.0 0.0 4.2 0.1 0.0 0.0 0.0 0.0 1.1 0.4 0.2 0.4 0.0 0.0 3972.6 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.7 0.5 0.0 0.0 2310.6 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 84.3 0.0 2.8 0.0 3758.4 176.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.7 2.3 6.6 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 327.1;Leydig cells: 972.3;Peritubular cells: 624.4;Skeletal myocytes: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 120.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" 138.5 48.5 11.3 22.3 10.9 8.3 98.8 1.7 13.3 334.6 9.6 144.5 59.2 309.6 44.7 100.6 246.8 39.3 401.9 10.7 14.2 64.7 37.4 242.5 24.8 16.2 10.3 315.2 37.2 22.6 75.9 38.3 16.4 253.6 38.2 3.7 82.8 126.3 63.0 73.0 135.4 74.4 11.3 80.5 125.3 78.5 14.2 12.9 173.2 156.7 14.0 188.6 374.5 15.3 19.8 21.3 41.7 56.5 15.1 16.0 6.6 7.7 24.9 7.8 6.4 6.4 43.8 22.4 34.9 13.1 12.4 26.3 10.6 26.8 2.6 61.0 3.3 7.3 53.7 2.4 49.4 3.0 23.1 19.9 21.7 15.6 27.8 41.0 4.9 21.6 46.7 120.3 1.9 19.7 3.1 1.3 4.9 56.1 24.9 51.9 1.1 35.6 3.9 1.7 1.8 17.4 28.3 21.5 7.4 6.4 11.9 11.3 20.4 1.3 81.4 2.6 16.7 26.8 24.9 7.1 35.1 28.5 20.4 0.0 1.5 0.4 8.1 2.4 5.5 3.5 7.7 6.5 2.7 2.0 3.2 3.4 0.3 3.0 1.3 5.0 5.5 2.3 11.3 10.9 1.7 13.3 10.7 14.2 16.2 10.3 16.4 11.3 14.2 15.3 84.7 6.4 14.1 2.0 11.6 57.6 30.9 62.8 56.3 60.4 13.0 18.2 15.5 17.2 18.5 22.0 0.0 1.5 12.7 38.2 1.9 6.3 11.1 14.8 154.7 29.9 4.2 12.4 8.1 4.7 2.6 327.1 37.2 24.2 10.2 13.5 102.4 3.3 7.5 40.4 11.3 42.2 6.1 6.4 39.6 39.0 972.3 13.9 58.7 15.0 9.5 3.5 16.5 2.0 14.0 6.9 16.6 624.4 16.5 23.6 97.7 0.3 7.1 3.2 59.2 229.2 52.8 50.7 36.3 38.2 29.1 2.6 24.9 10.2 36.4 27.2 LY75 "CD205, CLEC13B, DEC-205" ENSG00000054219 "Lymphocyte antigen 75" O60449 2 159803355-159904756 "CD markers, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 78.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 27.8;monocytes: 96.5;Proximal enterocytes: 33.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 21.8;HDLM-2: 21.7;Karpas-707: 85.3;RT4: 30.1;THP-1: 22.3" "CAB001450, HPA049108, HPA054073" Enhanced Approved "Golgi apparatus" NA NA 1300000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus" "CAB001450: AB_563525, HPA049108: AB_2680635, HPA054073: AB_2682370" "unprognostic (7.29e-3)" "unprognostic (1.92e-3)" "unprognostic (3.15e-1)" "unprognostic (1.52e-2)" "unprognostic (4.60e-3)" "unprognostic (3.65e-2)" "unprognostic (8.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.80e-1)" "unprognostic (2.36e-1)" "unprognostic (8.74e-3)" "unprognostic (3.92e-1)" "prognostic unfavorable (2.39e-5)" "unprognostic (2.66e-1)" "unprognostic (4.89e-2)" "unprognostic (1.94e-2)" "prognostic favorable (3.86e-4)" 2.0 1.9 1.1 18.7 1.0 9.6 9.4 1.1 1.2 7.3 0.7 12.4 18.0 2.6 0.7 5.0 8.5 7.7 1.0 0.9 1.3 3.7 2.0 7.7 30.3 1.7 1.1 1.0 1.4 1.1 0.6 1.3 1.6 1.8 11.9 0.7 7.8 2.6 0.3 7.4 17.6 2.3 1.8 18.4 7.1 0.4 1.2 78.4 17.3 0.9 22.1 10.3 2.2 1.8 3.5 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 9.1 21.8 15.7 0.7 0.0 0.0 0.4 0.0 0.1 0.0 21.7 0.0 4.4 0.2 0.1 0.4 3.3 0.1 0.3 0.1 0.6 0.2 0.0 11.1 0.0 0.0 85.3 0.0 0.0 0.0 5.8 0.5 0.5 0.0 6.0 0.0 3.8 6.4 30.1 0.0 0.0 7.0 5.0 0.0 0.2 0.0 22.3 16.7 0.0 0.0 0.0 0.0 13.2 2.4 3.0 0.0 7.7 0.0 2.6 1.2 2.4 4.2 1.7 4.6 3.7 3.8 4.8 2.9 2.7 4.3 5.1 3.7 5.2 0.7 1.0 3.0 1.4 1.1 1.0 1.1 1.2 0.9 1.3 1.7 1.1 1.6 1.8 1.2 1.8 1.7 0.0 3.4 0.0 15.4 7.5 2.2 5.6 7.4 0.2 9.9 12.1 0.5 4.3 6.3 23.9 2.1 0.1 10.6 27.8 0.0 0.8 0.6 15.4 1.3 3.3 1.8 6.9 0.0 5.5 0.1 1.8 8.6 9.4 11.4 1.7 2.2 0.2 3.9 0.0 0.0 9.8 4.1 10.1 11.3 0.3 2.5 11.5 5.4 0.0 96.5 0.2 13.4 0.0 0.0 4.9 10.9 0.4 8.1 1.3 33.5 2.0 20.7 0.2 0.0 3.7 1.3 0.0 0.7 4.5 6.7 0.3 14.2 0.9 12.3 5.6 LY75-CD302 ENSG00000248672 "LY75-CD302 readthrough" 2 159771851-159904710 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.4;intestine: 1.8;lymphoid tissue: 2.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 1.1;Club cells: 1.3;granulocytes: 1.3;Microglial cells: 1.0;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 7.0;HDLM-2: 7.4;Karpas-707: 27.6;RT4: 11.7;TIME: 7.3" HPA049108 Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA049108: AB_2680635" "unprognostic (2.53e-1)" "unprognostic (1.55e-1)" "unprognostic (2.33e-1)" "unprognostic (1.86e-1)" "unprognostic (9.04e-2)" "unprognostic (1.68e-4)" "unprognostic (1.14e-1)" "unprognostic (2.24e-1)" "unprognostic (3.32e-1)" "unprognostic (4.47e-2)" "unprognostic (1.88e-1)" 0.1 0.0 0.1 2.3 0.0 2.4 0.7 0.2 0.1 0.3 0.0 1.2 1.8 0.2 0.0 0.0 0.4 0.4 0.2 0.0 0.2 0.2 0.1 1.2 0.7 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.0 1.2 0.2 0.0 0.0 0.0 0.0 1.4 0.1 0.2 0.6 0.3 0.1 0.2 1.9 0.6 0.0 0.4 0.3 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 7.0 3.5 1.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 7.4 0.0 4.3 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.4 0.0 0.0 3.3 0.0 0.0 27.6 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.1 0.0 11.7 0.0 0.0 3.2 0.7 0.0 0.1 0.0 1.2 7.3 0.0 0.0 0.0 0.0 2.4 0.5 0.8 0.0 1.7 0.0 2.5 2.9 3.4 1.1 3.1 1.6 0.9 1.0 1.3 7.3 1.0 1.1 0.9 5.5 0.6 1.4 1.6 1.3 2.4 0.1 0.0 0.2 0.1 0.0 0.2 0.5 0.1 0.3 0.2 0.2 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LY96 MD-2 ENSG00000154589 "Lymphocyte antigen 96" Q9Y6Y9 8 73991392-74029079 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 570.8;Kupffer cells: 544.6;Langerhans cells: 155.4;Macrophages: 198.5;monocytes: 136.0;Plasma cells: 172.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 627.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 627.0" "Cell line enhanced" "Detected in many" "GAMG: 75.1;Karpas-707: 184.9;RPMI-8226: 94.0;U-87 MG: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053060 Approved Vesicles "Secreted to blood" NA NA 250000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA053060: AB_2682029" "unprognostic (2.96e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-1)" "unprognostic (1.85e-1)" "unprognostic (1.64e-2)" "unprognostic (2.87e-1)" "unprognostic (2.12e-3)" "unprognostic (1.42e-1)" "unprognostic (8.29e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.38e-11)" "unprognostic (2.87e-2)" "unprognostic (1.29e-2)" "unprognostic (1.60e-2)" "unprognostic (5.90e-2)" 28.6 12.4 12.9 42.4 13.5 17.9 24.7 13.1 22.7 12.9 13.8 15.7 12.3 10.5 5.4 9.0 11.1 35.3 9.5 13.0 14.4 13.2 22.8 22.0 47.4 16.3 14.8 22.6 3.7 2.4 8.0 44.9 14.9 6.1 14.5 1.2 11.4 6.7 3.8 4.4 9.9 20.3 14.7 59.6 10.6 4.7 13.9 16.2 7.3 9.8 39.3 30.5 7.9 17.1 1.5 0.0 0.3 0.2 34.5 73.2 0.1 49.5 61.9 13.5 31.1 0.0 0.5 15.9 16.7 32.6 75.1 0.5 0.2 0.6 34.4 17.1 0.3 0.3 0.0 1.8 17.5 2.7 0.9 21.2 0.4 21.9 4.3 2.2 67.2 9.7 0.2 184.9 48.9 0.0 6.5 2.1 0.2 0.0 1.0 6.4 0.0 94.0 2.5 0.0 0.3 0.2 0.0 0.2 6.5 0.3 0.0 3.3 52.1 33.5 2.6 18.0 12.1 48.1 24.7 9.6 92.3 1.0 14.7 13.7 90.2 0.4 0.5 85.1 1.3 26.3 12.8 1.9 45.8 15.1 8.2 2.9 627.0 0.2 71.8 37.6 21.6 30.6 12.9 13.5 13.1 22.7 13.0 14.4 16.3 14.8 14.9 14.7 13.9 17.1 35.1 16.0 10.7 0.0 48.4 13.8 1.2 1.3 0.0 0.2 11.2 4.4 2.4 0.0 9.7 3.7 0.0 2.7 16.3 0.1 0.0 6.8 24.2 0.3 1.0 63.6 0.0 14.1 2.8 7.4 3.1 32.9 0.0 0.3 3.8 0.0 104.2 3.3 570.8 0.0 3.9 0.0 2.0 544.6 155.4 3.1 14.3 198.5 76.5 21.5 136.0 0.0 1.0 0.5 1.1 9.4 0.0 6.8 172.6 0.8 0.0 1.1 5.6 0.2 6.6 20.0 14.0 0.7 0.2 2.2 11.6 6.4 21.8 12.4 0.3 1.4 MACROD2 "C20orf133, dJ631M13.5" ENSG00000172264 "Mono-ADP ribosylhydrolase 2" A1Z1Q3 20 13995369-16053197 "Metabolic proteins, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 349.7;Excitatory neurons: 752.7;Inhibitory neurons: 1058.5;Oligodendrocyte precursor cells: 672.0;Oligodendrocytes: 301.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 8.9;naive B-cell: 13.2;neutrophil: 3.4" "Group enriched" "Detected in many" 5 "B-cells: 13.2;granulocytes: 3.4" "Cell line enhanced" "Detected in many" "EFO-21: 15.5;Karpas-707: 19.1;RT4: 8.4;SCLC-21H: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049076 Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 37: B-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli" "HPA049076: " "unprognostic (1.70e-1)" "unprognostic (7.36e-2)" "unprognostic (1.59e-1)" "unprognostic (5.68e-3)" "unprognostic (2.03e-1)" "unprognostic (1.63e-3)" "unprognostic (1.24e-1)" "unprognostic (2.32e-2)" "unprognostic (3.02e-1)" "unprognostic (2.96e-2)" "unprognostic (4.02e-1)" "unprognostic (7.83e-2)" "unprognostic (4.15e-5)" "unprognostic (9.80e-2)" "unprognostic (9.91e-3)" "unprognostic (3.23e-1)" "unprognostic (2.02e-2)" 1.9 3.1 3.9 2.2 8.4 1.2 2.8 2.3 4.7 3.1 0.1 1.3 0.7 5.0 2.3 1.4 7.3 2.8 1.1 4.8 2.8 3.9 1.8 10.9 4.0 3.3 3.6 2.9 2.9 2.5 2.2 1.1 3.7 4.7 1.3 4.9 1.3 9.9 1.5 2.7 0.9 4.0 2.1 5.0 2.3 5.1 7.3 1.8 2.6 0.6 5.3 4.5 1.2 4.3 1.0 0.4 3.0 1.2 0.8 0.7 0.5 0.3 2.1 1.2 0.7 0.4 0.7 2.0 15.5 1.4 2.6 1.5 0.3 0.7 1.9 1.0 0.9 1.2 1.2 2.4 3.4 0.3 0.3 1.9 1.3 0.0 0.5 1.1 1.1 0.2 1.4 19.1 3.1 0.5 0.5 0.8 0.9 7.1 0.6 1.2 0.5 4.0 2.2 8.4 10.6 1.9 1.6 0.2 0.6 1.1 1.0 1.8 0.7 1.4 3.2 0.3 0.0 0.7 0.3 2.1 0.9 1.0 1.7 0.1 0.5 0.5 0.2 1.2 0.2 8.9 0.2 0.2 0.4 13.2 0.2 0.3 3.4 0.1 1.6 0.2 0.0 0.5 3.9 8.4 2.3 4.7 4.8 2.8 3.3 3.6 3.7 2.1 7.3 4.3 1.6 51.3 203.8 349.7 18.3 4.5 49.8 1.4 5.2 94.0 7.6 6.9 5.9 11.5 37.5 12.9 39.6 7.1 0.1 1.8 9.8 11.9 35.4 8.6 2.5 3.0 1.2 0.4 752.7 1.6 0.4 4.6 9.2 6.7 1.3 7.6 7.1 4.8 0.9 8.4 1058.5 4.5 0.0 0.3 2.1 62.2 3.4 0.9 3.6 87.1 0.0 10.2 0.0 672.0 301.4 6.6 1.7 17.7 2.8 6.2 2.4 8.6 9.8 20.3 6.6 2.1 6.0 23.7 18.8 5.8 6.7 2.1 0.9 13.2 2.8 5.4 MAGEB18 MGC33889 ENSG00000176774 "MAGE family member B18" Q96M61 X 26138343-26140736 "Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Spermatocytes: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 28 "Karpas-707: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA046141 Enhanced NA NA "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA046141: AB_2679554" "unprognostic (1.66e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGI2 "ACVRIP1, AIP1, ARIP1, KIAA0705, MAGI-2" ENSG00000187391 "Membrane associated guanylate kinase, WW and PDZ domain containing 2" Q86UL8 7 78017055-79453667 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.1" "Group enriched" "Detected in many" 7 "Astrocytes: 1765.2;Excitatory neurons: 2453.9;Inhibitory neurons: 2438.2;Oligodendrocyte precursor cells: 1208.9;Oligodendrocytes: 4001.5" "Cancer enriched" "Detected in many" 5 "glioma: 7.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "Karpas-707: 81.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013650 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA013650: AB_1853501" "unprognostic (4.32e-2)" "unprognostic (2.41e-2)" "unprognostic (1.62e-1)" "unprognostic (1.70e-4)" "unprognostic (5.04e-2)" "unprognostic (3.33e-1)" "unprognostic (6.57e-2)" "unprognostic (1.03e-1)" "unprognostic (2.17e-1)" "unprognostic (8.80e-3)" "unprognostic (1.64e-2)" "unprognostic (5.06e-2)" "prognostic favorable (1.08e-4)" "unprognostic (4.34e-4)" "unprognostic (2.17e-1)" "unprognostic (2.23e-2)" "unprognostic (3.01e-2)" 4.0 5.9 11.9 1.1 16.4 0.8 3.1 0.0 27.1 4.3 0.0 3.8 1.8 4.1 3.6 2.1 3.9 3.0 2.6 14.1 0.0 5.3 1.4 2.8 0.7 0.7 1.3 8.2 3.3 12.5 6.9 1.2 0.0 8.5 1.6 11.6 1.6 8.1 1.9 1.3 2.0 2.5 0.0 1.9 2.2 3.6 10.8 0.6 6.5 2.3 0.4 4.4 3.0 17.0 0.1 0.6 19.5 0.3 4.0 6.2 0.3 3.5 6.4 0.7 1.0 0.1 0.3 0.1 0.1 2.2 2.6 0.3 1.1 0.1 0.9 1.0 0.8 0.3 0.5 1.1 5.8 0.5 1.0 4.7 0.3 0.4 0.2 3.6 0.9 0.7 0.6 81.9 1.7 0.8 0.2 0.4 4.3 0.7 0.2 0.3 0.2 1.4 0.2 0.3 2.9 4.9 0.8 0.3 1.9 2.9 0.4 0.6 1.1 2.8 1.0 7.6 0.5 0.4 0.0 0.2 1.8 0.1 1.2 0.8 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.2 0.9 0.2 0.2 0.3 0.1 0.0 11.9 16.4 0.0 27.1 14.1 0.0 0.7 1.3 0.0 0.0 10.8 17.0 7.9 9.6 12.5 1765.2 0.3 1.0 1.3 0.6 6.2 29.3 3.2 6.7 7.5 4.3 3.3 1.8 20.9 0.4 0.7 1.6 5.9 0.4 25.1 9.1 18.3 5.8 2.4 0.0 2453.9 1.0 0.1 11.0 0.5 4.5 0.0 11.6 2.2 2.0 0.2 47.1 2438.2 1.6 0.0 0.0 0.3 32.5 6.5 1.0 1.8 327.9 0.0 24.5 0.0 1208.9 4001.5 0.4 1.5 19.9 0.5 3.5 1.1 1.7 2.1 23.3 13.1 11.0 12.8 4.8 0.9 1.3 1.0 0.4 0.7 8.9 1.4 0.7 MAGT1 "DKFZp564K142, IAP, MRX95, OST3B, SLC58A1" ENSG00000102158 "Magnesium transporter 1" Q9H0U3 X 77825747-77895593 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 145.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049851 Approved "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA049851: AB_2680913" "prognostic unfavorable (1.30e-4)" "unprognostic (3.32e-1)" "unprognostic (6.47e-2)" "unprognostic (1.16e-1)" "unprognostic (2.39e-1)" "unprognostic (3.81e-3)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (8.98e-4)" "unprognostic (2.03e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.03e-1)" "unprognostic (1.60e-2)" "unprognostic (5.56e-3)" "unprognostic (1.14e-1)" "unprognostic (6.25e-3)" "unprognostic (1.66e-1)" 25.3 22.6 12.9 24.2 19.4 20.8 36.5 17.2 17.4 39.4 14.4 28.3 25.7 27.5 53.7 25.6 25.9 25.1 37.5 13.0 16.4 41.9 71.2 26.8 22.5 20.9 18.5 23.6 31.9 38.4 18.5 36.4 21.9 33.5 27.0 5.2 34.6 28.0 17.1 18.3 26.2 24.3 16.6 23.5 29.4 11.3 17.9 21.0 78.0 21.9 23.5 29.1 18.2 27.0 62.5 34.1 41.7 48.8 75.0 49.3 64.8 66.9 67.4 51.7 56.5 45.6 99.5 45.6 90.9 71.7 53.3 56.4 88.4 50.8 80.0 32.3 55.4 30.6 46.2 42.5 66.6 64.9 31.1 45.3 43.5 64.6 56.7 55.1 74.0 31.2 36.5 123.2 64.7 40.4 36.2 23.9 56.1 64.6 41.3 43.3 72.5 84.7 61.9 45.8 14.1 26.3 91.6 64.8 58.0 43.6 43.8 35.3 75.2 45.6 51.1 71.7 33.2 44.8 103.1 58.1 49.7 60.5 61.0 15.3 12.9 13.7 17.2 19.7 18.4 12.5 15.6 16.6 11.1 10.7 14.9 17.7 11.0 18.6 21.0 22.2 12.8 15.7 12.9 19.4 17.2 17.4 13.0 16.4 20.9 18.5 21.9 16.6 17.9 27.0 50.2 41.7 53.6 9.8 37.3 33.0 55.3 51.6 24.5 5.2 39.1 25.1 53.4 42.9 51.6 40.5 4.2 33.3 43.4 44.8 3.9 35.3 2.2 23.7 38.9 40.7 22.7 33.0 6.1 34.9 59.3 43.7 33.1 58.0 30.4 24.5 43.2 145.6 42.3 1.7 6.3 39.6 32.6 49.8 46.1 2.5 30.7 45.1 33.8 15.9 33.9 17.1 18.6 13.6 28.0 36.2 37.2 27.1 87.4 65.4 31.2 32.0 20.7 5.2 19.7 38.7 31.2 6.6 16.7 36.5 45.6 81.3 36.0 31.2 26.0 69.4 MALRD1 "bA265G8.2, C10orf112, Diet1" ENSG00000204740 "MAM and LDL receptor class A domain containing 1" Q5VYJ5 10 19048801-19790401 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "intestine: 31.1" "Group enriched" "Detected in some" 4 "Astrocytes: 37.9;Oligodendrocyte precursor cells: 76.4;Proximal enterocytes: 69.3" "Cancer enhanced" "Detected in some" "breast cancer: 0.9;stomach cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "Karpas-707: 44.2" "Not detected" "Not detected" "HPA035732, HPA038106, HPA046848" Uncertain Enhanced "Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "HPA035732: AB_2674756, HPA038106: AB_2675836, HPA046848: AB_2679837" "unprognostic (9.03e-3)" "unprognostic (1.38e-1)" "unprognostic (2.40e-2)" "unprognostic (4.05e-3)" "unprognostic (2.49e-1)" "unprognostic (3.77e-1)" "unprognostic (2.74e-2)" "unprognostic (5.57e-2)" "unprognostic (5.01e-1)" "unprognostic (1.00e-1)" "unprognostic (3.55e-1)" "unprognostic (7.69e-2)" "unprognostic (3.16e-2)" "unprognostic (9.80e-2)" "unprognostic (8.90e-2)" "unprognostic (3.13e-2)" "unprognostic (3.78e-4)" 0.5 0.7 1.9 0.2 1.9 0.4 0.6 1.0 1.6 0.7 1.3 0.5 30.6 0.6 2.2 0.2 0.2 0.4 1.4 1.8 2.1 1.5 0.1 0.9 0.1 1.5 1.7 1.2 0.1 0.0 1.5 0.4 1.5 0.6 0.1 0.3 0.1 0.3 0.6 0.2 31.1 0.4 1.7 0.2 0.3 2.1 1.9 1.9 0.5 0.1 0.0 0.6 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.8 0.0 2.6 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 44.2 0.0 4.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.9 1.9 1.0 1.6 1.8 2.1 1.5 1.7 1.5 1.7 1.9 1.5 0.0 0.0 1.8 37.9 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.6 1.6 0.0 0.0 0.0 0.0 0.8 1.3 0.0 1.9 0.1 7.9 0.1 0.3 0.1 0.0 4.2 11.6 0.0 0.8 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 11.0 9.5 0.0 0.0 0.3 1.8 0.0 0.0 0.0 5.6 0.0 1.4 0.0 76.4 4.9 0.0 13.8 0.7 0.0 0.2 69.3 0.2 0.0 0.0 0.0 0.1 0.2 9.0 4.1 0.1 0.1 0.3 0.0 1.9 9.7 0.0 MAN2A1 "GOLIM7, MANA2" ENSG00000112893 "Mannosidase alpha class 2A member 1" Q16706 5 109689927-109869625 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 107.8" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 2117.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022377, HPA026896" Enhanced Supported "Golgi apparatus" NA NA 110000000 "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "CAB022377: , HPA026896: AB_1853512" "unprognostic (1.62e-2)" "unprognostic (4.06e-2)" "unprognostic (1.25e-2)" "unprognostic (6.96e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (4.20e-2)" "unprognostic (3.91e-1)" "unprognostic (2.90e-2)" "unprognostic (4.73e-2)" "unprognostic (1.23e-1)" "unprognostic (6.77e-3)" "unprognostic (2.03e-2)" "unprognostic (1.20e-2)" "unprognostic (1.11e-3)" "unprognostic (5.31e-3)" 11.2 17.0 28.0 13.9 66.1 12.7 11.3 41.4 29.6 13.8 3.8 20.7 30.1 12.0 4.2 8.5 9.0 18.1 3.7 21.7 31.5 17.4 42.4 10.1 15.8 64.5 49.9 9.8 22.2 20.7 0.9 15.3 62.1 9.1 20.8 1.7 6.5 10.2 6.0 7.4 25.7 18.3 39.4 14.1 15.7 9.5 42.8 22.7 14.7 11.5 14.7 16.1 2.7 107.8 23.1 18.6 26.5 11.0 56.2 42.2 97.5 49.3 78.0 26.1 46.7 23.2 37.0 17.4 30.7 63.3 18.5 26.5 14.5 56.0 59.7 16.3 9.7 32.6 13.5 30.7 34.6 15.9 15.5 39.7 25.0 43.4 61.4 37.3 54.5 16.9 8.8 87.0 70.5 13.8 27.6 9.1 20.4 17.9 7.3 10.8 40.0 78.5 34.1 32.8 3.7 3.3 22.6 24.9 16.1 29.1 20.5 17.1 56.4 53.7 21.3 30.1 32.9 48.7 58.7 13.6 41.8 22.4 30.3 4.1 2.0 0.6 1.6 2.8 1.3 1.9 2.8 2.8 1.8 1.6 3.3 2.7 1.6 0.5 4.4 2.0 2.8 1.1 28.0 66.1 41.4 29.6 21.7 31.5 64.5 49.9 62.1 39.4 42.8 107.8 20.9 6.4 8.4 100.9 41.1 17.8 15.8 12.7 29.6 0.6 20.0 9.5 7.6 34.3 14.7 31.3 0.0 19.4 28.9 65.8 1.9 27.1 13.7 10.2 35.8 21.6 24.7 29.2 220.8 35.3 98.0 32.3 45.3 33.3 15.2 19.2 36.8 130.3 18.0 0.0 115.2 35.2 22.4 74.8 24.6 8.3 9.9 47.4 26.6 102.1 39.6 5.9 13.4 46.8 2117.7 28.8 28.4 6.8 84.0 39.8 60.6 24.7 12.1 0.2 19.7 52.6 16.5 16.5 19.9 33.6 23.7 23.7 34.7 14.2 49.6 24.2 MAP3K5 "ASK1, MAPKKK5, MEKK5" ENSG00000197442 "Mitogen-activated protein kinase kinase kinase 5" Q99683 6 136557046-136792477 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 88.1" "Cell type enhanced" "Detected in many" "Astrocytes: 383.6;Excitatory neurons: 170.4;Inhibitory neurons: 204.8;Microglial cells: 216.4;Oligodendrocyte precursor cells: 210.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007824, HPA063245" Supported Supported Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "CAB007824: AB_598175, HPA063245: AB_2684969" "unprognostic (1.37e-1)" "unprognostic (3.21e-2)" "unprognostic (2.85e-2)" "unprognostic (1.38e-1)" "unprognostic (3.19e-1)" "prognostic favorable (6.08e-4)" "unprognostic (8.76e-2)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.91e-4)" "unprognostic (3.97e-1)" "unprognostic (3.75e-2)" "unprognostic (1.37e-1)" "unprognostic (2.72e-1)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" 13.2 88.1 21.7 11.7 23.6 14.1 9.5 21.6 18.9 8.4 7.0 8.7 7.3 11.3 7.7 10.0 12.9 7.5 11.3 18.6 18.9 10.6 9.0 11.9 12.1 17.2 20.7 49.3 30.9 1.9 16.2 5.3 16.1 18.0 9.7 14.5 7.1 7.1 6.3 8.0 9.0 5.1 16.6 11.7 14.8 12.0 24.8 8.2 12.8 6.1 12.3 18.5 9.2 15.7 5.6 3.4 0.0 0.0 7.6 20.2 1.9 8.0 42.6 4.0 3.8 0.3 5.6 3.3 11.5 11.1 3.0 7.6 13.6 4.1 10.5 4.6 10.6 28.9 7.6 0.0 36.3 13.6 0.1 26.8 5.3 6.3 17.9 15.4 13.6 4.1 7.3 31.2 28.7 10.9 0.3 11.6 1.3 10.9 4.5 7.6 8.9 13.2 16.2 35.3 9.7 6.4 6.6 6.3 1.8 1.4 1.4 12.0 12.0 6.7 2.1 0.4 7.5 25.3 18.0 0.0 5.3 18.6 6.0 3.5 1.8 2.1 1.5 1.4 2.9 1.1 2.5 2.2 1.5 1.5 0.2 0.8 5.2 2.3 1.4 1.5 4.6 0.9 21.7 23.6 21.6 18.9 18.6 18.9 17.2 20.7 16.1 16.6 24.8 15.7 11.9 6.4 22.0 383.6 14.3 5.0 20.5 32.0 3.4 18.2 10.0 5.0 21.2 4.3 35.1 11.0 6.2 1.0 25.9 12.3 3.9 3.0 6.4 17.3 31.4 7.7 34.8 14.9 170.4 23.1 1.1 12.1 20.9 62.5 5.7 67.7 9.7 11.2 8.0 0.0 204.8 18.2 14.2 23.5 10.2 4.2 23.6 26.6 0.0 216.4 21.7 43.3 12.3 210.1 4.2 17.8 8.7 14.3 13.5 18.8 7.2 8.3 20.5 2.6 13.1 5.3 17.9 3.4 15.5 13.1 10.1 2.7 18.5 16.2 11.2 23.4 MBD2 ENSG00000134046 "Methyl-CpG binding domain protein 2" Q9UBB5 18 54151606-54224669 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 5.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037282, HPA067582, HPA067615" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB037282: AB_477234, HPA067582: AB_2685866, HPA067615: AB_2685872" "unprognostic (4.86e-2)" "unprognostic (7.21e-2)" "prognostic favorable (6.49e-4)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "unprognostic (2.47e-1)" "unprognostic (2.38e-3)" "unprognostic (2.35e-2)" "unprognostic (2.71e-2)" "unprognostic (2.36e-3)" "unprognostic (8.04e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (8.70e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-3)" "unprognostic (5.19e-2)" 26.9 10.5 6.5 19.2 8.9 20.3 19.9 9.5 9.4 16.0 6.5 17.3 12.0 11.3 15.8 29.5 11.3 11.5 14.9 6.8 8.9 16.7 16.9 16.4 32.1 7.6 8.3 11.4 17.4 16.5 9.2 18.8 7.7 13.4 16.4 14.3 19.4 15.1 15.4 25.4 15.5 11.9 7.0 21.2 13.9 31.5 7.9 20.1 31.0 16.8 35.2 21.0 20.1 8.2 29.1 13.2 23.2 11.7 27.3 23.0 22.5 26.5 33.9 30.6 26.6 8.5 15.8 68.7 13.1 42.1 13.5 45.1 20.1 36.6 33.4 50.2 11.1 10.2 20.4 18.3 28.2 32.7 17.7 20.2 40.3 23.5 34.1 20.3 35.9 20.7 8.0 62.0 28.0 14.0 33.1 18.1 24.2 11.3 17.2 21.8 13.9 27.9 44.5 29.9 25.6 10.8 21.0 21.1 14.7 30.3 10.9 16.3 31.2 31.1 14.1 10.9 24.4 65.1 38.3 52.5 27.4 27.4 19.0 0.0 1.4 0.7 0.6 2.6 0.9 0.7 0.7 1.0 0.8 1.3 0.3 0.6 1.2 0.2 5.0 0.7 1.5 0.4 6.5 8.9 9.5 9.4 6.8 8.9 7.6 8.3 7.7 7.0 7.9 8.2 71.1 28.9 21.0 30.3 44.9 49.3 37.3 21.2 13.1 19.3 46.0 35.3 35.8 24.3 23.0 33.1 16.7 14.3 57.6 51.2 7.9 26.3 1.9 62.1 48.9 38.0 16.3 22.7 42.5 58.4 49.4 32.7 21.9 103.3 8.2 32.0 32.2 25.2 30.3 21.9 38.3 35.9 10.2 142.6 38.7 4.8 25.1 82.2 26.6 43.1 69.3 45.9 8.2 32.2 49.5 54.3 28.0 26.4 53.7 51.5 35.7 23.5 30.0 27.0 26.3 39.0 35.2 6.5 6.1 54.6 62.5 18.3 47.7 43.0 38.7 79.5 MCF2L2 "ARHGEF22, KIAA0861" ENSG00000053524 "MCF.2 cell line derived transforming sequence-like 2" Q86YR7 3 183178043-183428778 "Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 33.5;retina: 28.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 79.0;Cone photoreceptor cells: 221.0;Early spermatids: 92.9;Excitatory neurons: 177.2;Inhibitory neurons: 149.9;Oligodendrocyte precursor cells: 185.5;Oligodendrocytes: 69.1;Rod photoreceptor cells: 124.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.6" "Lineage enriched" "Detected in single" 15 "T-cells: 1.6" "Cell line enhanced" "Detected in some" "HDLM-2: 6.0;Karpas-707: 5.0;REH: 3.4" "Low region specificity" "Detected in all" "HPA038946, HPA038947, HPA061485" Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Centriolar satellite, Cytosol" "HPA038946: AB_10670914, HPA038947: AB_10672655, HPA061485: " "unprognostic (2.17e-2)" "unprognostic (4.42e-1)" "unprognostic (3.08e-1)" "unprognostic (1.95e-3)" "unprognostic (1.98e-1)" "unprognostic (2.87e-2)" "unprognostic (3.70e-2)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (5.08e-2)" "unprognostic (4.80e-4)" "unprognostic (1.32e-1)" "unprognostic (8.75e-6)" "unprognostic (1.09e-1)" "unprognostic (5.47e-2)" "unprognostic (2.95e-1)" "unprognostic (1.78e-1)" 0.1 7.7 9.4 0.3 16.5 0.2 0.1 0.3 33.5 0.3 0.0 0.5 0.0 0.2 0.2 0.2 0.2 0.3 0.2 13.5 6.5 0.4 0.0 0.2 0.5 6.9 6.1 0.2 0.2 3.8 5.4 0.0 7.2 0.6 0.3 28.2 0.1 0.4 0.3 0.2 0.3 0.3 0.0 2.5 0.2 2.6 5.6 0.3 0.1 0.2 0.7 0.4 0.3 19.8 0.0 0.4 0.1 1.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.7 0.1 1.0 0.1 0.0 1.2 0.0 0.2 0.1 0.0 6.0 0.9 2.5 0.2 0.0 0.1 0.8 0.5 0.1 0.0 0.0 0.4 0.0 0.4 1.5 0.8 5.0 0.3 0.7 0.8 0.5 0.8 0.0 1.0 3.4 0.0 0.9 0.2 0.1 1.5 0.5 0.6 0.0 1.3 0.3 0.3 0.5 0.3 0.0 0.5 0.0 0.0 2.0 2.3 1.1 0.5 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.6 0.0 9.4 16.5 0.3 33.5 13.5 6.5 6.9 6.1 7.2 0.0 5.6 19.8 12.3 0.0 2.2 17.0 0.2 0.4 0.5 0.2 8.6 79.0 0.3 0.6 1.8 0.0 0.1 5.5 221.0 0.2 0.8 2.1 0.0 0.1 92.9 4.6 2.1 2.0 0.0 0.4 177.2 0.2 0.1 2.0 5.1 4.3 1.3 7.7 1.8 0.4 0.5 8.4 149.9 0.3 2.0 0.8 1.2 16.4 0.9 4.3 1.8 43.1 1.6 3.8 1.0 185.5 69.1 0.1 2.2 0.4 0.6 0.3 0.4 0.1 2.8 124.0 0.0 4.1 0.9 1.4 4.2 11.2 0.4 1.4 2.9 2.9 0.2 1.1 MED26 "CRSP7, CRSP70" ENSG00000105085 "Mediator complex subunit 26" O95402 19 16574907-16629062 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.9" "Cell type enhanced" "Detected in many" "Early spermatids: 65.4;Late spermatids: 67.4;Spermatocytes: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057997, HPA071835" Enhanced Approved Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA057997: AB_2732618, HPA071835: AB_2686455" "unprognostic (2.02e-2)" "prognostic favorable (2.46e-4)" "unprognostic (2.47e-2)" "unprognostic (2.57e-3)" "unprognostic (1.42e-1)" "unprognostic (3.60e-3)" "unprognostic (5.03e-2)" "unprognostic (3.77e-2)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.99e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (5.50e-5)" "unprognostic (9.43e-3)" "unprognostic (1.64e-1)" "unprognostic (5.14e-2)" "unprognostic (5.98e-3)" 4.5 3.8 4.4 3.8 4.0 11.0 4.1 5.1 4.7 4.0 4.0 4.1 2.4 4.3 1.8 5.2 3.2 2.3 3.2 5.0 5.1 2.8 3.7 4.0 4.9 5.2 4.7 4.7 3.9 3.5 3.6 3.2 4.7 4.2 1.9 2.0 4.5 2.4 6.9 6.4 3.6 2.5 3.6 4.7 3.6 35.9 4.5 4.4 3.1 3.2 4.6 3.9 4.6 4.2 11.1 4.2 3.8 8.3 4.8 3.8 11.1 6.3 4.4 6.7 6.0 6.3 6.5 17.6 6.5 4.0 2.1 8.2 5.9 6.3 4.6 13.0 12.2 6.9 4.2 5.1 4.7 7.9 6.3 4.6 6.1 5.7 5.9 4.0 3.6 9.1 11.5 20.7 4.2 11.1 8.4 7.4 9.0 5.2 13.4 8.7 5.8 19.3 4.0 4.3 10.0 5.4 5.5 5.3 6.4 2.7 3.9 10.3 4.5 8.5 6.8 10.4 8.5 14.3 12.6 14.4 6.0 10.4 5.0 0.7 0.1 0.1 0.5 0.3 0.1 0.4 0.0 0.2 0.2 0.7 0.3 0.0 0.3 0.4 0.1 1.4 0.7 0.1 4.4 4.0 5.1 4.7 5.0 5.1 5.2 4.7 4.7 3.6 4.5 4.2 13.7 3.2 12.7 11.4 11.8 14.1 5.0 3.8 11.4 4.2 14.3 12.2 1.1 2.8 3.0 5.5 10.4 6.2 15.8 5.9 3.9 4.4 65.4 12.9 7.7 6.1 2.4 5.0 8.6 4.0 11.1 7.0 5.6 16.6 1.3 5.8 4.2 5.6 5.0 5.0 7.6 4.7 2.0 8.5 10.7 67.4 6.5 9.9 1.8 1.9 4.9 6.0 4.1 7.1 8.5 6.0 3.0 3.8 15.9 6.7 3.6 2.0 3.5 6.4 0.0 17.7 8.0 54.1 19.4 11.5 10.7 16.8 11.0 6.1 5.1 8.7 MID2 "FXY2, MRX101, RNF60, TRIM1" ENSG00000080561 "Midline 2" Q9UJV3 X 107825755-107931637 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.5;Inhibitory neurons: 21.5;Urothelial cells: 11.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 6 "T-cells: 1.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 41.5;Karpas-707: 35.5;MCF7: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (8.28e-2)" "unprognostic (8.51e-2)" "unprognostic (3.69e-4)" "unprognostic (6.40e-3)" "unprognostic (1.16e-1)" "unprognostic (7.50e-2)" "unprognostic (3.87e-1)" "unprognostic (7.20e-2)" "unprognostic (1.09e-2)" "unprognostic (4.87e-2)" "unprognostic (2.00e-1)" "unprognostic (2.09e-1)" "unprognostic (3.19e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.07e-1)" "unprognostic (3.77e-1)" "unprognostic (5.97e-3)" 11.2 9.2 5.2 3.9 6.1 0.4 7.2 4.4 4.2 8.3 4.2 6.0 1.8 9.4 8.0 13.6 8.8 7.7 3.1 3.5 12.1 6.0 5.4 6.4 4.4 7.4 7.1 9.3 9.6 12.9 3.2 4.4 9.1 10.3 3.6 14.8 11.1 9.6 12.9 9.6 2.6 15.8 6.3 3.8 4.4 2.1 9.0 2.3 13.2 18.5 5.2 10.6 7.5 4.8 8.4 7.1 0.2 11.2 8.8 12.3 0.1 5.9 15.0 5.0 3.6 0.6 1.5 0.0 7.5 11.7 8.3 5.2 4.1 12.1 1.1 0.0 5.5 0.0 4.2 0.0 13.5 0.0 0.0 8.0 13.3 0.1 14.5 9.1 41.5 0.5 0.0 35.5 5.6 26.8 0.1 0.0 1.2 0.3 13.0 0.0 3.2 0.0 6.3 7.5 0.6 0.0 12.6 0.5 18.6 3.9 4.6 0.5 8.2 0.0 2.1 9.9 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.0 0.8 1.4 0.0 0.2 1.6 1.1 0.0 0.0 0.0 0.0 0.1 0.4 5.2 6.1 4.4 4.2 3.5 12.1 7.4 7.1 9.1 6.3 9.0 4.8 3.1 3.2 0.0 8.1 0.4 3.1 3.3 0.9 4.0 1.9 2.3 1.8 0.6 1.5 1.1 0.0 0.0 0.0 0.3 0.3 1.9 1.8 1.1 1.0 1.7 2.6 0.0 0.0 14.5 1.5 0.0 1.5 1.1 1.5 0.0 0.3 2.2 1.8 0.1 0.0 21.5 0.2 0.0 0.0 0.0 1.4 0.0 0.2 3.6 7.5 0.0 0.8 0.0 8.0 7.4 1.1 0.0 0.7 1.1 4.2 0.5 0.8 2.3 3.9 0.0 1.9 2.1 0.2 0.4 3.9 3.7 0.0 1.7 0.8 0.4 11.4 MINPP1 MIPP ENSG00000107789 "Multiple inositol-polyphosphate phosphatase 1" Q9UNW1 10 87504875-87553461 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Erythroid cells: 288.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026859 Approved "Intracellular and membrane" NA NA 370000000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA026859: AB_1853961" "unprognostic (9.15e-2)" "unprognostic (8.76e-3)" "unprognostic (2.08e-2)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" "unprognostic (5.20e-3)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (4.55e-1)" "unprognostic (2.07e-2)" "unprognostic (6.54e-2)" "unprognostic (6.50e-3)" "prognostic unfavorable (6.98e-5)" "unprognostic (2.43e-1)" "unprognostic (2.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.01e-2)" 8.5 21.3 6.6 7.2 6.7 31.1 9.4 6.9 9.1 8.8 9.4 12.6 17.6 7.0 10.0 3.6 8.5 8.4 5.8 6.8 8.0 17.5 29.1 8.3 7.7 6.4 6.8 8.8 11.9 9.0 8.1 18.9 6.4 11.7 12.9 11.9 6.9 7.6 4.9 9.1 13.6 7.6 6.9 6.9 8.5 7.9 7.7 8.1 11.6 5.7 7.0 8.6 5.7 7.4 18.6 28.1 28.1 40.9 46.4 38.1 23.2 29.5 51.1 28.8 38.3 15.0 35.5 16.4 27.0 35.9 19.4 28.2 29.9 27.1 33.2 37.1 35.7 41.1 10.4 55.7 34.6 18.0 36.0 33.7 34.7 32.6 19.5 52.5 37.0 14.3 24.5 75.9 34.4 13.8 11.9 25.6 20.0 14.2 20.2 0.0 15.8 11.0 38.5 10.4 10.2 31.5 28.1 5.9 51.5 31.5 16.7 14.7 32.4 18.3 21.9 22.1 28.7 24.5 27.1 4.2 29.3 26.8 13.7 10.5 10.8 4.9 11.5 13.8 10.1 8.7 10.8 13.0 14.3 8.2 10.2 11.4 0.7 11.7 12.5 8.2 17.3 10.5 6.6 6.7 6.9 9.1 6.8 8.0 6.4 6.8 6.4 6.9 7.7 7.4 11.7 6.4 12.8 9.1 8.1 2.8 8.3 25.5 8.0 14.4 9.0 4.3 4.9 15.7 16.2 7.3 2.1 20.4 4.9 14.0 5.9 17.2 15.9 7.1 13.4 10.5 13.1 288.9 18.3 16.7 19.2 17.9 7.1 6.7 24.7 17.8 16.4 58.3 12.9 10.1 20.8 25.5 20.3 16.0 5.8 4.0 9.3 8.7 10.6 7.5 11.7 11.1 10.3 25.6 19.1 10.5 17.2 8.2 18.6 6.8 17.1 26.0 19.0 14.8 0.0 4.8 11.1 10.6 12.1 4.0 3.4 8.1 8.2 13.7 11.6 4.4 MIOX ALDRL6 ENSG00000100253 "Myo-inositol oxygenase" Q9UGB7 22 50486784-50490648 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "kidney: 700.9" "Cell type enriched" "Detected in some" 10 "Proximal tubular cells: 4564.6" "Cancer enriched" "Detected in many" 16 "renal cancer: 56.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 24.9;Hep G2: 5.7;Karpas-707: 12.8;U-266/70: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039451, HPA039562" Enhanced NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039451: AB_2676513, HPA039562: AB_2676574" "unprognostic (2.11e-1)" "unprognostic (4.32e-2)" "unprognostic (2.22e-2)" "unprognostic (1.30e-2)" "unprognostic (9.83e-2)" "unprognostic (5.25e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-3)" "unprognostic (2.84e-1)" "unprognostic (4.72e-2)" "unprognostic (1.85e-2)" "unprognostic (9.83e-2)" "prognostic favorable (2.60e-6)" "unprognostic (1.77e-1)" "unprognostic (1.50e-1)" "unprognostic (1.36e-2)" "unprognostic (2.23e-2)" 0.2 0.1 0.1 0.3 0.2 0.2 0.0 0.8 0.5 0.0 0.2 0.8 0.2 0.0 0.2 0.1 0.0 5.3 0.0 0.2 0.2 700.9 0.4 0.0 0.7 0.2 0.2 0.0 1.2 0.0 0.1 0.1 0.3 0.5 0.0 0.1 0.3 0.1 0.0 0.3 0.2 0.0 0.1 0.2 1.1 0.2 0.2 0.2 14.7 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.3 0.2 0.1 2.0 0.2 0.0 0.0 0.1 0.1 0.2 0.1 0.6 0.4 0.0 0.2 0.2 0.0 0.0 24.9 0.0 0.2 0.4 5.7 2.8 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 1.1 0.1 12.8 0.0 1.2 0.0 0.1 0.2 0.5 0.4 0.1 0.1 0.1 2.6 0.1 0.1 0.3 0.0 0.0 0.6 0.5 0.1 1.4 0.0 0.0 0.5 0.1 0.1 7.8 0.7 0.3 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.8 0.5 0.2 0.2 0.2 0.2 0.3 0.1 0.2 0.3 0.2 0.0 1.7 0.0 13.0 0.8 0.9 0.1 0.0 0.6 0.7 0.8 0.1 1.5 0.0 99.3 0.0 0.0 0.3 0.3 424.6 0.0 0.0 0.1 0.2 0.2 1.2 0.0 0.0 0.9 0.1 0.3 0.0 0.2 0.0 0.1 0.4 0.3 0.1 0.0 0.0 0.9 0.0 0.0 1.6 0.0 0.0 23.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 4564.6 0.0 0.5 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.3 7.8 0.0 0.1 0.9 MRPL54 ENSG00000183617 "Mitochondrial ribosomal protein L54" Q6P161 19 3762682-3768575 "Predicted intracellular proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 427.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042117, HPA046767" Uncertain Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA042117: AB_2677856, HPA046767: AB_2679795" "unprognostic (2.09e-1)" "unprognostic (1.00e-3)" "unprognostic (3.81e-2)" "unprognostic (1.85e-3)" "unprognostic (1.00e-1)" "unprognostic (4.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.32e-3)" "unprognostic (7.19e-2)" "unprognostic (1.70e-2)" "unprognostic (2.22e-2)" "unprognostic (2.88e-2)" "unprognostic (1.34e-3)" "unprognostic (1.78e-1)" "unprognostic (2.26e-1)" "unprognostic (2.64e-2)" "unprognostic (6.54e-3)" 56.1 85.5 68.9 41.0 69.0 109.0 54.8 70.6 80.0 47.0 70.5 54.9 53.8 49.8 36.3 58.4 57.8 34.6 78.6 67.5 70.4 78.7 122.9 43.1 63.5 69.5 68.4 46.9 87.8 71.3 64.0 31.4 69.8 57.9 44.0 38.1 71.9 37.1 57.8 55.9 48.8 37.6 69.8 54.4 70.7 54.4 70.1 63.4 57.8 57.8 50.5 50.4 43.8 72.0 115.1 64.4 58.4 57.6 34.2 54.6 49.6 53.8 69.0 126.8 108.5 55.7 39.8 82.1 54.4 66.8 47.6 71.3 77.6 70.9 53.8 53.0 118.4 41.8 33.6 72.0 89.1 89.7 95.0 64.2 121.3 53.2 92.7 49.0 105.8 56.4 80.2 157.1 67.3 77.9 81.1 94.5 77.8 79.8 46.9 69.4 33.2 122.8 97.8 57.9 81.6 67.6 43.8 103.4 83.4 27.8 69.7 126.6 75.5 79.5 45.8 136.5 117.2 95.4 140.5 82.4 78.6 142.3 60.6 96.9 121.2 81.9 103.4 132.8 96.0 139.1 112.5 122.3 134.7 125.8 107.6 99.1 35.3 133.0 133.7 122.7 168.4 144.1 68.9 69.0 70.6 80.0 67.5 70.4 69.5 68.4 69.8 69.8 70.1 72.0 61.1 76.9 79.3 5.5 101.2 49.1 91.9 111.1 63.2 55.6 89.2 98.8 55.2 91.5 91.7 79.1 18.8 134.4 69.7 183.5 358.1 112.7 94.2 90.1 54.7 60.5 105.4 63.1 3.6 193.6 125.7 62.8 90.7 78.8 106.5 47.6 62.4 249.8 157.7 38.7 4.7 234.8 79.3 115.3 65.4 63.0 56.2 90.9 71.2 2.8 120.7 105.1 106.1 2.0 10.1 128.7 185.4 44.8 123.2 116.2 234.4 427.8 76.0 90.9 26.3 65.7 64.4 113.4 47.1 106.7 57.3 176.9 94.6 109.3 171.5 118.2 MUS81 "FLJ44872, SLX3" ENSG00000172732 "MUS81 structure-specific endonuclease subunit" Q96NY9 11 65857126-65867653 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 130.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059530 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoli fibrillar center" Nucleoplasm "HPA059530: AB_2684052" "unprognostic (2.34e-3)" "unprognostic (2.52e-1)" "unprognostic (8.68e-2)" "unprognostic (1.35e-1)" "unprognostic (6.31e-2)" "unprognostic (1.87e-1)" "prognostic unfavorable (6.05e-4)" "unprognostic (2.06e-1)" "unprognostic (7.18e-2)" "unprognostic (5.24e-2)" "unprognostic (9.64e-2)" "unprognostic (4.27e-2)" "unprognostic (1.05e-3)" "unprognostic (5.37e-2)" "unprognostic (2.98e-1)" "unprognostic (1.20e-1)" "unprognostic (8.86e-2)" 20.6 18.0 15.2 13.3 15.6 11.3 20.3 15.7 20.0 32.0 14.4 31.4 16.9 35.4 7.7 16.9 30.8 10.9 25.3 14.6 13.4 28.8 19.4 21.6 18.6 16.6 15.6 29.8 19.9 10.2 22.4 11.0 15.9 26.2 7.1 8.1 16.6 15.9 24.3 14.1 23.7 12.4 14.8 29.0 22.5 16.6 16.7 16.1 23.5 16.9 13.6 29.7 22.5 18.8 21.6 13.3 22.1 22.0 9.5 11.5 28.2 22.7 17.9 28.2 18.8 17.7 34.4 20.4 30.0 17.8 35.2 20.6 19.9 19.9 6.3 44.5 14.7 37.3 39.8 10.8 29.0 26.9 38.2 18.3 36.2 35.8 28.0 20.7 24.0 36.5 22.9 55.4 18.7 14.2 38.1 41.0 16.1 14.1 29.2 37.2 10.6 39.7 21.5 13.3 22.1 25.3 15.5 27.7 48.7 13.5 32.6 27.3 21.5 21.2 18.0 27.3 24.9 37.6 26.9 29.7 24.1 17.5 36.3 22.6 13.7 27.4 21.0 16.3 21.0 13.1 15.9 18.4 14.7 10.4 12.3 15.4 9.4 13.3 18.5 14.7 15.1 13.0 15.2 15.6 15.7 20.0 14.6 13.4 16.6 15.6 15.9 14.8 16.7 18.8 19.3 12.8 18.4 15.0 17.2 8.0 21.5 13.5 10.2 19.2 11.8 15.6 10.0 11.5 16.0 7.3 20.9 20.8 22.0 27.0 5.9 24.7 62.8 12.2 22.0 16.1 16.8 25.7 9.0 22.2 23.6 13.5 27.0 13.0 14.0 15.0 16.8 9.2 19.6 23.5 8.8 23.9 10.2 13.3 8.8 130.0 21.8 14.3 10.6 9.4 27.1 15.0 32.0 8.5 12.9 26.6 24.5 27.1 12.6 11.0 36.1 12.4 16.0 24.7 39.5 11.5 21.9 27.9 16.7 8.4 7.4 19.7 19.9 15.0 21.4 10.2 MYBPC2 "fsMyBP-C, MGC163408, MYBPCF" ENSG00000086967 "Myosin binding protein C2" Q14324 19 50432892-50466321 "Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "skeletal muscle: 4338.8;tongue: 1199.2" "Cell type enriched" "Detected in some" 29 "Skeletal myocytes: 56.9" "Cancer enriched" "Detected in some" 9 "head and neck cancer: 9.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "HDLM-2: 58.7;Karpas-707: 143.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042991 Enhanced NA NA 420000 "Cluster 37: B-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "HPA042991: AB_2678257" "unprognostic (6.48e-3)" "unprognostic (2.65e-3)" "unprognostic (6.25e-2)" "unprognostic (3.26e-3)" "unprognostic (1.91e-3)" "unprognostic (2.15e-2)" "unprognostic (6.22e-3)" "unprognostic (2.46e-1)" "unprognostic (5.38e-2)" "unprognostic (9.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (2.19e-8)" "unprognostic (1.85e-1)" "unprognostic (5.74e-2)" "unprognostic (2.73e-3)" "unprognostic (2.73e-1)" 0.3 0.0 0.2 1.1 0.2 0.3 0.4 0.2 0.4 0.0 0.1 0.4 0.0 0.0 0.0 4.2 0.1 0.0 0.3 0.2 0.4 0.3 0.1 0.2 1.1 0.4 0.4 0.1 0.3 212.6 0.2 0.0 0.5 6.7 0.2 0.0 12.5 0.0 4338.8 0.8 0.4 0.0 0.2 0.3 0.2 0.3 0.3 1.4 1.0 1199.2 1.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 58.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 143.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.4 0.2 0.4 0.4 0.4 0.5 0.2 0.3 0.1 0.0 0.0 0.5 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.1 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 56.9 0.5 0.2 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 MYDGF "C19orf10, IL-25, IL-27, IL25, IL27, IL27w, R33729_1, SF20" ENSG00000074842 "Myeloid derived growth factor" Q969H8 19 4641374-4670362 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 768.1;Plasma cells: 857.6;Syncytiotrophoblasts: 581.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 1043.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041872, HPA046744" Approved "Secreted to blood" NA NA 285000 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA041872: AB_2677718, HPA046744: AB_2679783" "unprognostic (3.14e-1)" "unprognostic (1.32e-2)" "unprognostic (1.73e-1)" "prognostic favorable (6.50e-7)" "unprognostic (4.14e-1)" "unprognostic (1.35e-1)" "unprognostic (1.08e-2)" "unprognostic (1.71e-1)" "unprognostic (5.11e-2)" "unprognostic (4.56e-2)" "unprognostic (8.19e-2)" "unprognostic (4.54e-2)" "prognostic unfavorable (4.99e-12)" "unprognostic (4.42e-1)" "unprognostic (3.24e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" 84.7 94.2 42.5 83.8 43.5 92.0 73.2 44.4 48.7 79.1 47.6 81.4 75.7 75.1 114.6 67.5 71.0 44.1 66.3 43.1 48.1 70.8 259.5 91.7 61.9 45.7 44.0 72.1 210.0 41.7 126.1 76.1 45.8 84.2 65.5 13.0 135.6 52.8 24.7 59.3 71.1 52.9 45.5 123.0 94.5 54.5 45.0 30.8 75.4 15.1 45.5 74.3 63.3 50.2 250.5 118.7 74.6 189.8 228.0 190.2 133.0 449.6 378.1 210.8 263.8 194.9 155.8 145.0 206.5 455.4 171.9 122.7 88.6 157.7 121.8 137.7 152.0 87.6 212.7 250.0 353.9 310.9 201.6 159.0 187.8 154.6 292.3 263.0 233.0 78.8 155.4 1043.7 194.9 134.4 83.9 174.1 94.5 235.3 417.1 80.0 126.3 701.0 169.1 114.2 114.1 117.0 151.0 189.1 227.5 64.2 111.4 366.6 268.9 162.8 135.1 449.2 325.9 505.8 229.6 122.2 401.8 405.8 260.1 156.8 216.6 82.6 148.7 232.2 151.6 123.6 118.7 121.1 264.0 101.0 99.8 107.0 13.8 151.5 209.0 426.0 96.3 225.2 42.5 43.5 44.4 48.7 43.1 48.1 45.7 44.0 45.8 45.5 45.0 50.2 134.4 44.8 68.1 4.6 185.1 0.0 160.1 0.0 46.1 31.0 153.8 133.9 6.6 110.1 18.6 77.3 4.2 284.0 135.6 39.8 43.0 355.9 8.7 65.9 168.2 131.9 31.5 55.3 7.3 351.1 768.1 177.0 92.8 158.8 16.4 135.8 126.7 207.3 415.6 26.9 9.6 96.2 0.0 118.8 0.0 12.8 140.5 155.4 0.0 9.4 250.8 51.3 116.4 8.0 10.6 401.8 71.3 91.0 857.6 342.0 182.9 86.8 9.5 32.7 92.1 92.7 157.1 183.2 125.1 64.4 0.0 581.6 84.9 145.5 101.0 260.7 MYO5A "GS1, MYH12, MYO5, MYR12" ENSG00000197535 "Myosin VA" Q9Y4I1 15 52307283-52529050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.1;parathyroid gland: 47.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 353.0;Inhibitory neurons: 241.0;Oligodendrocyte precursor cells: 330.8;Oligodendrocytes: 404.2" "Cancer enhanced" "Detected in all" "melanoma: 25.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 201.0;RPMI-8226: 140.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001356 Enhanced Approved "Focal adhesion sites,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites, Centriolar satellite" "HPA001356: AB_1079441" "unprognostic (1.54e-1)" "unprognostic (1.78e-1)" "unprognostic (6.95e-2)" "unprognostic (2.29e-2)" "unprognostic (1.97e-2)" "unprognostic (3.91e-2)" "unprognostic (2.30e-2)" "unprognostic (6.65e-2)" "unprognostic (7.89e-2)" "unprognostic (4.74e-2)" "unprognostic (9.36e-3)" "unprognostic (1.71e-1)" "unprognostic (5.63e-3)" "unprognostic (3.79e-3)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "prognostic unfavorable (4.22e-4)" 10.3 8.3 17.0 12.1 20.8 21.8 6.5 3.0 39.1 6.8 0.0 6.1 3.8 5.0 3.7 5.3 4.0 8.5 5.8 19.0 3.6 5.3 2.9 8.8 15.0 9.6 4.2 5.7 5.2 47.4 8.9 6.3 9.8 5.1 5.9 26.1 5.2 3.5 5.4 11.8 5.0 9.4 0.0 9.5 4.7 5.9 6.6 11.0 8.4 5.0 13.1 9.7 5.3 20.8 19.5 33.7 17.6 21.3 16.2 19.3 19.0 34.7 31.1 18.1 14.0 3.2 7.8 18.7 8.9 41.8 26.5 15.7 40.7 35.6 22.3 105.5 9.6 16.7 8.8 4.2 8.3 9.0 16.3 13.0 21.9 26.6 52.4 17.6 106.8 12.0 0.7 201.0 34.8 34.4 8.2 1.2 8.1 0.5 26.6 14.5 27.8 140.8 15.1 14.0 12.7 7.8 32.3 26.2 59.4 13.1 14.0 9.1 52.0 36.4 15.7 17.1 34.1 20.9 49.9 22.0 39.4 25.1 53.5 0.4 2.4 3.1 1.4 1.7 2.1 1.1 1.3 0.9 2.7 0.7 0.2 0.4 3.0 0.3 1.4 1.5 2.2 1.1 17.0 20.8 3.0 39.1 19.0 3.6 9.6 4.2 9.8 0.0 6.6 20.8 11.2 12.8 11.4 68.2 19.8 20.8 9.3 10.5 7.4 75.1 6.7 5.5 12.1 2.8 19.8 14.7 39.6 0.6 18.4 0.3 0.0 5.4 18.0 9.3 8.0 12.7 1.2 2.5 353.0 6.3 0.4 7.5 3.1 6.7 22.8 5.0 2.5 1.3 24.4 26.9 241.0 0.2 2.0 27.1 28.0 10.8 3.7 50.2 97.8 52.5 36.7 6.0 15.5 330.8 404.2 6.1 2.5 1.9 32.4 10.2 0.0 2.8 11.1 28.7 6.6 16.7 10.8 14.0 9.4 3.9 11.6 1.1 23.7 2.1 0.3 7.3 NABP1 "DKFZp667M1322, FLJ13624, FLJ22833, hSSB2, MGC111163, OBFC2A, SOSS-B2, SSB2" ENSG00000173559 "Nucleic acid binding protein 1" Q96AH0 2 191678068-191741097 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 36.7" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 452.0;Langerhans cells: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 76.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054978, HPA067802" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA054978: AB_2682660, HPA067802: AB_2685899" "unprognostic (5.43e-2)" "unprognostic (5.33e-2)" "unprognostic (2.80e-1)" "unprognostic (4.73e-2)" "unprognostic (1.48e-1)" "unprognostic (6.89e-2)" "unprognostic (8.07e-4)" "unprognostic (1.33e-1)" "unprognostic (2.89e-2)" "unprognostic (2.99e-1)" "unprognostic (2.82e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (8.20e-7)" "unprognostic (5.64e-2)" "unprognostic (7.50e-2)" "unprognostic (1.48e-1)" "unprognostic (6.02e-2)" 22.0 5.3 2.3 23.2 1.8 5.5 9.8 1.5 2.4 4.7 4.9 5.2 10.0 4.6 0.6 13.2 5.4 7.4 3.9 2.5 2.5 10.5 9.8 21.1 12.4 2.7 2.7 4.5 3.8 0.8 4.3 7.6 2.5 4.4 3.8 1.0 5.2 3.2 2.8 4.4 18.8 3.7 2.2 36.7 4.7 9.2 5.1 6.3 3.2 3.3 11.6 18.4 7.6 3.6 36.2 5.5 1.5 1.6 15.7 16.4 10.2 53.4 31.3 28.6 15.1 30.9 18.7 2.6 43.1 26.3 23.9 11.5 5.7 22.1 29.0 21.2 5.5 18.4 10.8 5.6 14.3 9.8 16.5 22.5 20.3 47.9 23.4 13.8 8.3 4.8 28.7 76.3 31.8 3.3 3.5 10.8 3.6 6.8 31.4 7.1 6.1 16.8 30.2 22.2 2.0 1.3 21.3 7.7 14.1 18.7 2.7 4.7 31.4 28.2 24.6 15.4 33.6 25.2 12.7 9.1 25.1 9.7 6.4 20.0 10.4 8.8 13.2 17.1 19.1 10.8 17.3 13.7 7.3 3.5 8.0 10.7 38.8 6.6 21.5 6.9 28.5 8.5 2.3 1.8 1.5 2.4 2.5 2.5 2.7 2.7 2.5 2.2 5.1 3.6 42.2 214.7 452.0 2.0 66.5 53.0 141.0 15.7 32.5 3.3 33.1 34.3 9.3 8.6 106.2 11.0 2.1 23.6 46.9 79.0 3.9 16.7 212.8 64.9 28.1 34.0 4.2 9.1 3.5 5.7 43.5 62.2 32.1 179.6 139.6 2.2 10.8 8.6 54.9 3.3 3.6 20.2 8.2 113.8 301.8 69.9 10.2 151.3 40.9 18.7 108.8 1.9 18.6 1.5 1.7 30.7 85.7 3.8 43.9 44.8 109.2 22.4 57.6 3.6 6.6 101.5 46.3 25.7 18.4 35.6 45.3 146.3 111.6 12.2 31.7 112.8 NBPF10 AG1 ENSG00000271425 "NBPF member 10" 1 146064711-146229000 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Alveolar cells type 2: 46.1;Basal keratinocytes: 57.0;Langerhans cells: 100.9;Suprabasal keratinocytes: 105.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Microtubules "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (2.05e-1)" "unprognostic (8.84e-2)" "unprognostic (5.84e-2)" "unprognostic (5.61e-3)" "unprognostic (1.06e-1)" "unprognostic (5.16e-3)" "unprognostic (3.26e-1)" "unprognostic (2.17e-1)" "unprognostic (9.49e-2)" "unprognostic (6.64e-5)" "unprognostic (1.60e-1)" "unprognostic (6.01e-2)" "unprognostic (1.11e-3)" "unprognostic (2.19e-1)" "unprognostic (1.61e-1)" "unprognostic (9.61e-2)" "unprognostic (6.68e-2)" 3.7 1.1 3.4 2.8 2.8 7.6 4.3 2.2 6.4 4.9 7.4 2.8 1.1 3.5 3.8 2.8 3.0 2.2 1.3 3.6 2.2 1.9 3.2 3.3 2.5 3.8 3.1 5.4 3.3 3.2 0.3 2.5 2.9 2.7 2.8 4.6 2.0 3.0 1.0 7.4 1.2 3.4 1.7 4.4 1.8 3.3 4.5 2.7 2.3 2.2 2.4 2.2 1.4 4.1 6.4 1.7 3.6 2.4 11.3 13.6 3.0 3.3 4.5 3.3 3.3 1.5 3.0 2.7 0.7 6.4 3.2 3.0 4.0 4.5 6.7 3.4 3.0 6.3 5.0 0.8 4.5 2.7 1.9 12.4 4.1 9.2 8.8 10.6 3.9 1.7 2.0 8.7 7.1 7.3 1.1 2.4 1.5 1.6 4.7 1.4 2.6 3.6 2.3 4.5 0.4 0.4 5.1 4.9 1.8 5.8 4.2 3.6 12.3 3.2 2.9 2.9 4.4 5.8 2.3 3.4 2.9 2.9 2.7 2.2 2.0 2.7 0.3 1.0 0.4 1.5 0.3 0.3 0.8 1.5 0.3 0.2 5.6 0.3 2.3 2.2 0.3 0.1 3.4 2.8 2.2 6.4 3.6 2.2 3.8 3.1 2.9 1.7 4.5 4.1 0.5 76.9 46.1 13.7 12.8 57.0 4.9 15.4 5.2 0.5 3.7 2.0 8.4 2.8 22.0 0.0 0.0 0.7 9.2 1.5 0.0 5.3 15.1 2.8 2.8 3.4 0.0 10.5 0.8 2.7 5.0 18.2 3.1 6.1 20.2 6.4 0.7 1.8 1.4 0.0 1.1 2.7 14.2 5.0 100.9 3.3 6.5 17.7 30.2 4.7 14.2 2.0 9.2 5.0 0.1 5.5 25.3 8.2 5.7 2.1 2.2 0.2 19.6 2.0 0.0 7.6 9.9 9.9 5.4 23.8 105.8 0.5 6.6 1.4 3.4 4.5 NECAP2 FLJ10420 ENSG00000157191 "NECAP endocytosis associated 2" Q9NVZ3 1 16440721-16460078 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 314.8;monocytes: 202.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028077 Approved Approved "Endoplasmic reticulum" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Endoplasmic reticulum" "HPA028077: AB_10601273" "unprognostic (6.92e-2)" "unprognostic (4.45e-2)" "unprognostic (1.11e-1)" "unprognostic (2.73e-2)" "unprognostic (1.28e-1)" "unprognostic (4.35e-1)" "prognostic unfavorable (6.13e-4)" "unprognostic (5.48e-2)" "unprognostic (1.57e-1)" "unprognostic (3.38e-1)" "unprognostic (6.72e-2)" "unprognostic (1.70e-1)" "unprognostic (4.36e-2)" "unprognostic (1.39e-1)" "unprognostic (2.17e-1)" "unprognostic (5.58e-2)" "unprognostic (2.58e-2)" 38.1 37.9 28.4 51.7 31.0 29.0 34.3 30.7 32.8 31.6 29.5 30.9 23.4 22.8 19.2 43.5 32.8 30.5 22.2 27.0 30.4 33.2 31.7 51.7 77.6 34.6 29.5 36.8 22.1 23.7 19.8 59.9 31.5 25.4 29.5 14.2 26.6 21.0 8.6 45.7 32.0 30.2 32.0 73.3 30.5 33.7 32.5 55.9 25.7 12.8 63.3 44.4 31.1 32.7 54.1 29.2 30.5 36.0 60.6 65.0 17.9 59.6 83.3 76.8 67.9 32.1 87.1 47.8 70.4 111.2 35.4 35.8 43.1 60.3 63.9 100.0 44.3 46.7 33.4 44.6 78.9 59.8 41.7 73.0 61.6 54.7 44.9 66.2 129.1 54.4 67.0 153.7 69.1 35.3 55.8 63.3 26.6 41.1 41.9 61.2 27.0 79.6 76.9 30.5 19.1 48.6 46.4 27.1 61.9 45.1 30.9 66.1 148.0 49.2 26.8 57.4 41.1 72.5 74.5 47.9 41.6 85.7 49.0 90.2 173.1 112.3 96.1 241.2 95.6 108.8 165.8 114.5 120.1 98.8 168.2 106.6 68.2 121.6 274.7 71.0 214.7 269.9 28.4 31.0 30.7 32.8 27.0 30.4 34.6 29.5 31.5 32.0 32.5 32.7 53.6 22.4 25.0 10.1 47.6 52.3 34.1 60.4 27.3 25.7 37.9 35.1 7.0 22.8 32.2 20.2 314.8 49.0 42.5 34.6 23.5 71.3 61.1 27.0 29.5 67.8 18.7 40.8 7.0 54.2 62.0 33.3 23.9 27.6 27.8 33.0 96.4 11.0 125.7 15.2 7.7 31.8 36.7 94.5 81.8 34.3 29.8 60.5 24.9 7.5 202.0 23.8 55.6 11.6 11.4 121.9 45.8 33.8 24.3 46.6 30.8 22.8 37.4 54.3 39.5 14.7 27.2 26.8 27.4 33.3 56.0 49.4 59.4 72.7 24.0 58.8 NEK1 "KIAA1901, NY-REN-55" ENSG00000137601 "NIMA related kinase 1" Q96PY6 4 169392809-169612627 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Ciliopathy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 162.6;Excitatory neurons: 126.3;Inhibitory neurons: 170.5;Oligodendrocytes: 196.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020873, HPA040413" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Centriolar satellite" "HPA020873: AB_10671583, HPA040413: AB_10671169" "unprognostic (4.10e-2)" "unprognostic (2.97e-1)" "unprognostic (1.59e-2)" "unprognostic (1.97e-1)" "unprognostic (6.98e-2)" "unprognostic (3.10e-1)" "unprognostic (3.95e-1)" "unprognostic (3.29e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (4.06e-3)" "unprognostic (2.21e-1)" "prognostic favorable (1.42e-4)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.10e-2)" "unprognostic (3.46e-1)" 6.0 6.1 5.1 4.9 6.8 4.2 5.2 7.1 5.3 7.6 2.7 4.0 3.2 7.3 2.8 4.6 9.3 6.1 6.9 3.5 8.8 5.9 4.2 4.6 5.3 7.5 7.7 9.4 4.0 6.5 2.9 4.3 7.6 6.7 4.4 8.7 4.2 6.0 3.3 2.3 3.5 6.6 7.6 5.1 4.9 11.8 5.3 6.8 7.9 4.6 4.6 5.6 2.8 7.7 5.8 2.5 10.0 11.0 15.5 17.1 3.3 11.9 10.6 9.3 8.8 3.3 6.7 15.4 2.2 10.4 9.0 1.9 9.7 10.1 10.5 16.9 6.5 10.3 10.4 3.9 9.0 10.6 7.9 13.7 5.9 9.5 16.7 19.1 9.3 14.5 18.6 28.2 12.1 3.7 13.6 4.6 3.3 3.6 6.0 8.4 6.5 4.9 9.7 6.8 11.0 12.5 8.6 4.2 8.1 7.7 5.3 4.6 11.2 6.0 5.4 6.2 8.1 11.3 18.6 11.6 9.7 5.1 10.7 5.1 0.9 0.9 1.9 1.5 2.2 2.0 1.5 1.2 0.7 2.0 2.2 2.3 0.6 1.1 0.7 1.6 1.6 0.7 5.1 6.8 7.1 5.3 3.5 8.8 7.5 7.7 7.6 7.6 5.3 7.7 12.2 12.8 16.4 162.6 34.2 9.6 15.8 12.1 21.1 21.8 11.3 12.7 37.2 4.3 17.8 18.4 29.2 20.8 17.0 6.4 17.6 10.4 109.7 67.2 21.6 13.2 7.2 26.7 126.3 6.2 8.6 25.0 17.3 23.7 18.3 20.1 9.7 7.8 10.7 18.5 170.5 5.6 20.3 7.0 7.4 48.2 23.6 14.5 5.4 53.4 6.6 26.1 15.5 115.1 196.1 8.9 4.0 31.6 23.2 6.9 5.3 9.6 68.4 24.9 13.1 32.8 25.5 67.9 37.3 21.3 6.3 29.6 22.0 26.0 6.3 9.2 NEMP1 "KIAA0286, TMEM194, TMEM194A" ENSG00000166881 "Nuclear envelope integral membrane protein 1" O14524 12 57055643-57088063 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014394 Uncertain Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA014394: AB_2204899" "unprognostic (9.24e-2)" "unprognostic (1.78e-1)" "unprognostic (1.18e-1)" "unprognostic (4.97e-2)" "unprognostic (1.43e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.93e-4)" "unprognostic (8.36e-2)" "unprognostic (2.42e-3)" "unprognostic (2.11e-1)" "unprognostic (1.64e-1)" "unprognostic (6.61e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.31e-2)" "unprognostic (9.51e-2)" "unprognostic (2.63e-2)" "unprognostic (7.05e-2)" 6.2 5.1 3.3 8.0 3.5 6.8 6.3 3.6 3.9 6.6 3.7 8.7 3.8 8.2 5.3 5.6 6.3 4.3 3.0 3.2 3.3 4.3 6.1 6.3 12.2 3.3 3.2 7.2 4.0 3.7 3.5 7.8 3.7 6.8 6.8 9.3 4.5 5.2 2.3 10.8 7.5 7.4 3.3 7.3 5.4 7.7 3.2 16.1 5.4 3.0 11.6 6.5 5.7 4.2 20.0 16.8 37.5 40.5 12.3 12.0 21.5 30.2 17.1 41.1 33.3 20.0 37.2 47.2 38.1 10.4 35.0 28.8 50.4 13.0 47.0 25.3 22.9 27.9 19.5 10.6 5.2 35.0 30.7 4.1 12.3 33.8 21.0 17.1 11.6 42.2 57.5 91.2 35.0 10.9 38.5 29.7 21.0 18.8 18.4 38.5 53.2 21.5 9.0 12.2 22.3 15.1 25.7 21.3 24.1 26.4 38.5 34.7 8.3 39.0 22.5 36.4 28.6 40.8 83.2 40.5 23.1 32.9 41.1 2.4 0.5 0.8 1.1 1.5 1.5 1.9 1.2 1.5 0.5 1.6 1.8 1.6 0.2 2.4 0.9 0.9 1.2 0.8 3.3 3.5 3.6 3.9 3.2 3.3 3.3 3.2 3.7 3.3 3.2 4.2 4.7 22.4 2.6 0.0 7.1 0.0 3.1 0.0 8.0 2.6 5.0 2.9 1.6 2.8 1.8 5.5 4.2 5.0 4.1 1.4 0.0 1.8 1.2 3.3 4.4 4.0 0.0 12.2 0.0 0.8 3.6 4.4 3.1 3.7 0.0 11.1 5.7 3.6 5.8 1.7 0.0 1.8 0.0 7.1 0.0 1.0 6.2 7.2 0.0 0.0 4.4 3.5 3.1 0.0 0.0 2.0 0.7 5.3 4.9 4.1 1.0 1.3 2.9 4.0 13.1 3.6 3.4 12.2 7.4 7.6 0.0 3.0 4.1 3.1 2.2 2.4 NEXMIF "KIAA2022, KIDLIA, MRX98, XPN" ENSG00000050030 "Neurite extension and migration factor" Q5QGS0 X 74732856-74925472 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.6;Breast glandular cells: 1.4;Club cells: 2.5;Hofbauer cells: 1.3;Respiratory ciliated cells: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HAP1: 3.7;Karpas-707: 5.9;SiHa: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000407 Uncertain Supported "Nucleoplasm,Midbody,Mitotic spindle,Cytosol" Yes NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Midbody, Mitotic spindle, Cytosol" "HPA000407: AB_2665984" "unprognostic (1.04e-3)" "unprognostic (6.07e-5)" "unprognostic (1.81e-2)" "unprognostic (2.07e-5)" "unprognostic (2.15e-1)" "unprognostic (2.18e-2)" "unprognostic (3.37e-1)" "unprognostic (1.74e-3)" "unprognostic (3.71e-1)" "unprognostic (1.79e-2)" "unprognostic (1.64e-3)" "unprognostic (8.25e-2)" "unprognostic (7.58e-3)" "unprognostic (1.37e-2)" "unprognostic (3.80e-2)" "unprognostic (2.79e-4)" "unprognostic (6.94e-4)" 0.1 0.9 3.0 0.1 3.1 0.0 0.3 1.0 2.5 0.4 0.0 0.8 0.1 0.5 0.2 0.3 0.3 0.1 0.0 2.6 6.7 0.7 0.0 0.1 0.1 0.3 0.7 0.4 1.5 1.8 1.7 0.1 0.5 0.9 0.3 1.0 0.4 0.6 0.0 0.3 0.4 0.7 0.2 0.1 0.6 0.2 4.8 0.0 0.4 0.1 0.1 0.2 0.2 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 5.9 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.1 1.0 2.5 2.6 6.7 0.3 0.7 0.5 0.2 4.8 0.7 0.3 0.0 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.6 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.9 0.1 0.4 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 2.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 NFKB2 "LYT-10, NF-kB2, p105, p49/p100, p52" ENSG00000077150 "Nuclear factor kappa B subunit 2" Q00653 10 102394110-102402524 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 122.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 168.0;Karpas-707: 157.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008422, CAB022098, HPA023900" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol Nucleoplasm "CAB022098: , HPA008422: AB_1854434, HPA023900: AB_1854435" "unprognostic (1.10e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (1.53e-2)" "unprognostic (8.08e-3)" "unprognostic (2.15e-1)" "unprognostic (2.38e-3)" "unprognostic (3.98e-2)" "prognostic favorable (8.45e-5)" "unprognostic (4.04e-1)" "unprognostic (8.34e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.69e-12)" "unprognostic (2.37e-3)" "unprognostic (1.63e-1)" "unprognostic (4.90e-2)" "unprognostic (1.56e-1)" 26.5 21.0 7.6 44.4 7.4 69.3 19.6 7.1 9.2 22.9 8.5 39.1 15.5 21.6 2.3 17.7 20.4 18.5 20.6 7.2 7.2 34.6 28.2 41.0 40.7 8.5 7.5 21.4 24.1 6.1 10.8 14.7 8.0 29.0 6.8 1.1 21.3 9.1 18.4 20.0 26.5 12.2 7.5 50.6 22.7 10.0 8.4 16.9 20.1 7.6 25.7 37.0 19.1 8.0 67.9 48.6 7.7 31.7 11.1 16.6 19.3 18.5 61.0 19.6 25.9 28.6 55.2 32.9 43.5 11.9 48.8 40.9 20.5 28.2 6.8 168.0 11.2 7.0 11.7 15.9 30.1 5.1 45.5 22.0 14.6 34.1 32.3 26.5 7.8 16.1 7.6 157.8 7.4 26.4 7.1 22.7 10.3 15.7 16.6 16.8 24.5 27.0 34.3 22.1 1.7 8.2 16.2 36.7 26.3 7.2 29.3 16.4 21.2 19.0 28.9 25.4 47.0 113.1 105.0 32.6 31.1 14.8 10.9 0.0 1.3 0.0 0.7 0.9 0.7 2.6 0.8 0.7 0.7 2.1 0.8 0.8 5.6 0.8 2.1 0.6 1.1 0.5 7.6 7.4 7.1 9.2 7.2 7.2 8.5 7.5 8.0 7.5 8.4 8.0 20.8 9.6 8.8 3.3 88.3 43.5 59.3 41.2 34.7 2.2 17.1 14.5 3.1 25.8 29.9 18.4 16.7 6.3 39.0 33.3 5.9 33.2 1.1 33.7 14.4 26.1 16.3 0.4 0.1 21.0 15.8 26.0 80.0 52.0 71.8 5.5 11.7 3.7 20.9 0.0 0.1 30.4 22.4 19.4 122.9 1.7 7.5 52.5 30.2 1.9 75.1 3.9 12.3 1.5 0.7 44.9 37.4 4.9 49.1 49.3 33.2 8.6 19.9 5.3 0.0 36.4 43.6 4.7 11.1 17.5 44.6 23.1 54.6 8.8 17.9 45.6 NKAIN2 "FAM77B, TCBA1" ENSG00000188580 "Sodium/potassium transporting ATPase interacting 2" Q5VXU1 6 123803865-124825640 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "brain: 56.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1721.6;Inhibitory neurons: 636.4;Oligodendrocytes: 2869.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "BEWO: 2.1;Daudi: 3.0;HEL: 6.4;Karpas-707: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045860 Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA045860: AB_10983192" "unprognostic (3.09e-2)" "unprognostic (1.06e-2)" "unprognostic (2.33e-2)" "unprognostic (4.53e-3)" "unprognostic (5.67e-2)" "unprognostic (1.01e-1)" "unprognostic (1.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.19e-1)" "unprognostic (5.41e-3)" "unprognostic (2.02e-3)" "unprognostic (2.61e-1)" "unprognostic (5.95e-3)" "unprognostic (3.63e-3)" "unprognostic (1.77e-1)" "unprognostic (1.66e-1)" "unprognostic (1.63e-1)" 0.9 0.4 24.2 0.1 33.6 0.7 0.3 30.1 39.3 0.3 9.8 1.0 0.0 0.1 0.3 0.2 0.3 0.2 1.1 29.2 25.3 0.1 0.2 0.2 0.2 40.7 28.0 0.1 0.1 0.0 1.8 0.1 37.4 0.2 0.1 6.6 0.3 0.2 2.9 0.1 0.3 0.3 34.8 0.1 0.2 0.4 28.8 0.5 0.1 3.4 0.2 0.5 0.3 56.8 0.0 0.0 1.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 6.4 0.0 0.0 0.4 0.0 0.0 1.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 10.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.2 33.6 30.1 39.3 29.2 25.3 40.7 28.0 37.4 34.8 28.8 56.8 0.5 0.0 0.0 97.3 0.0 0.1 0.0 0.2 0.0 3.0 0.0 0.1 1.3 0.0 0.1 0.0 2.1 0.2 0.0 0.0 0.0 0.1 1.7 0.2 0.1 0.3 1.8 2.1 1721.6 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.1 47.1 636.4 0.1 0.0 0.0 0.0 0.0 0.3 1.0 0.0 47.8 0.0 15.8 0.0 19.1 2869.5 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.2 1.1 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 NLRP1 "CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1" ENSG00000091592 "NLR family pyrin domain containing 1" Q9C000 17 5499427-5619424 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 561.7;Muller glia cells: 151.8" "Cancer enhanced" "Detected in all" "glioma: 20.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 55.4;Karpas-707: 90.9;U-266/70: 45.0" "CAB009189, HPA064431" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Cytosol" "CAB009189: , HPA064431: AB_2685262" "unprognostic (4.40e-2)" "unprognostic (1.02e-1)" "unprognostic (3.16e-2)" "unprognostic (3.65e-2)" "unprognostic (4.00e-2)" "unprognostic (1.23e-3)" "unprognostic (4.13e-2)" "unprognostic (1.50e-2)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "prognostic favorable (7.57e-4)" "unprognostic (2.99e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (6.69e-2)" "unprognostic (1.26e-1)" "unprognostic (1.26e-1)" "unprognostic (1.34e-2)" 27.9 4.0 3.6 27.8 3.7 25.0 22.1 3.2 5.3 22.9 3.5 10.8 5.8 13.8 1.8 16.2 14.4 13.4 15.7 2.9 3.7 9.4 5.3 26.9 38.1 5.5 3.8 5.8 3.2 1.8 4.1 12.1 5.5 13.2 7.8 0.3 10.8 9.0 7.7 50.8 31.1 9.7 3.7 56.3 6.9 6.1 4.0 15.1 21.8 7.7 32.4 15.8 27.7 4.1 14.2 0.0 0.0 0.0 8.6 10.2 1.8 6.9 6.3 2.6 5.7 0.2 5.5 5.3 20.8 7.6 1.1 6.5 0.0 23.4 4.0 55.4 0.0 1.4 4.8 0.5 7.1 0.0 1.6 6.6 14.5 20.7 13.7 10.4 25.6 1.1 13.0 90.9 11.8 0.0 0.1 4.6 0.0 0.0 0.3 6.0 4.0 23.0 0.0 4.8 0.7 0.0 0.0 0.2 0.4 0.6 0.0 0.5 25.2 5.3 3.0 3.2 1.1 45.0 15.9 4.1 8.7 0.6 0.3 18.3 7.1 5.0 5.9 4.9 6.6 4.4 5.1 6.3 5.0 4.9 5.5 5.2 18.9 4.2 8.6 0.5 7.7 4.6 3.6 3.7 3.2 5.3 2.9 3.7 5.5 3.8 5.5 3.7 4.0 4.1 46.4 0.0 7.8 1.3 29.0 17.7 7.1 8.0 15.4 60.6 2.7 6.2 4.9 2.8 10.4 7.3 4.2 0.8 30.3 0.3 3.9 0.4 561.7 4.9 18.0 26.9 77.9 3.6 2.9 0.0 1.1 31.6 3.6 1.0 3.8 7.8 44.6 0.6 7.0 85.8 1.5 1.2 0.0 23.0 24.3 93.4 25.4 26.2 7.2 56.2 27.0 151.8 26.8 1.5 0.8 7.0 0.0 28.2 25.9 2.0 0.0 0.4 12.7 11.6 6.6 33.1 17.3 25.0 11.0 10.7 24.9 1.5 37.6 3.6 0.2 8.0 NMRK1 "bA235O14.2, C9orf95, FLJ20559, NRK1" ENSG00000106733 "Nicotinamide riboside kinase 1" Q9NWW6 9 75060573-75088217 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 68.6;Karpas-707: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049795 Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" Centrosome "HPA049795: AB_2680886" "unprognostic (1.12e-1)" "unprognostic (4.13e-2)" "unprognostic (3.58e-2)" "prognostic favorable (3.70e-6)" "unprognostic (3.56e-2)" "unprognostic (2.35e-1)" "unprognostic (5.20e-3)" "unprognostic (2.21e-2)" "unprognostic (3.27e-2)" "unprognostic (2.43e-1)" "unprognostic (2.06e-2)" "unprognostic (1.78e-1)" "prognostic favorable (5.60e-4)" "unprognostic (9.25e-2)" "unprognostic (1.76e-1)" "unprognostic (5.28e-2)" "unprognostic (5.64e-2)" 22.1 11.5 14.6 14.3 15.0 12.6 20.2 17.0 18.9 21.8 15.4 15.3 17.8 11.2 18.5 39.5 16.4 14.1 15.5 15.2 15.4 32.5 53.7 21.7 17.5 14.9 14.8 22.7 45.1 64.1 19.8 14.8 15.2 23.7 13.0 8.8 31.2 13.6 27.2 23.2 22.4 8.8 14.8 31.1 26.0 9.7 14.4 17.3 25.6 13.4 20.0 18.8 25.6 15.2 11.7 2.7 3.2 7.9 21.4 28.0 18.1 17.0 22.4 3.5 5.8 0.1 29.8 6.8 10.0 13.8 7.2 18.5 3.8 9.4 10.0 68.6 3.5 5.1 5.6 5.7 20.3 4.8 0.8 22.5 23.5 6.3 11.8 20.8 25.1 10.8 0.5 79.0 24.6 8.4 4.3 4.3 3.9 40.2 10.0 1.6 29.7 42.1 28.9 19.5 2.2 0.5 7.3 6.4 9.0 19.2 18.4 4.5 20.6 13.5 2.9 12.9 4.6 37.5 31.4 4.1 23.1 4.9 13.8 16.4 5.4 9.3 25.1 5.1 30.5 13.4 43.7 29.2 6.1 9.1 39.4 30.2 9.8 17.2 14.5 17.2 31.6 18.1 14.6 15.0 17.0 18.9 15.2 15.4 14.9 14.8 15.2 14.8 14.4 15.2 42.2 38.5 21.7 11.8 22.6 21.0 36.4 38.2 38.7 8.4 33.4 37.5 15.5 21.5 27.9 23.9 8.4 53.3 43.7 32.8 52.8 30.5 17.8 42.4 16.8 33.4 4.2 10.3 26.2 35.5 75.7 22.7 49.5 37.4 1.3 8.3 55.3 45.2 62.4 11.8 20.6 34.8 22.4 32.5 9.6 30.8 23.6 22.9 26.6 14.0 67.6 15.2 43.3 13.6 23.9 21.5 26.1 12.4 68.8 23.4 83.8 92.1 30.5 8.3 13.1 24.5 15.0 10.7 8.3 50.9 27.0 45.6 48.8 22.2 25.0 32.6 NPAS4 "bHLHe79, Le-PAS, NXF, PASD10" ENSG00000174576 "Neuronal PAS domain protein 4" Q8IUM7 11 66421004-66426707 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 170.4" "Group enriched" "Detected in some" 4 "Bipolar cells: 10.2;Horizontal cells: 11.8;Rod photoreceptor cells: 5.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 13 "cerebellum: 170.4;cerebral cortex: 55.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 4.9;cerebellum: 5.0;cerebral cortex: 7.5;hippocampal formation: 4.6;olfactory bulb: 3.8" HPA039255 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA039255: AB_10674282" "unprognostic (7.81e-2)" "unprognostic (9.93e-2)" "unprognostic (1.55e-2)" "unprognostic (1.24e-1)" "unprognostic (2.51e-1)" "unprognostic (1.78e-3)" "unprognostic (4.97e-1)" "unprognostic (7.84e-2)" "unprognostic (1.85e-2)" "unprognostic (3.29e-2)" "unprognostic (3.96e-2)" "unprognostic (1.12e-3)" "unprognostic (1.58e-1)" "unprognostic (1.37e-1)" "unprognostic (4.24e-1)" "unprognostic (3.21e-2)" 0.2 0.2 0.8 0.4 2.9 0.0 0.1 170.4 55.3 0.8 0.5 2.7 0.1 3.3 0.1 0.3 1.3 0.1 0.2 4.2 8.6 0.1 0.1 0.1 0.0 2.2 1.6 0.3 0.3 0.0 19.3 0.0 3.6 1.2 0.1 0.1 0.1 0.7 0.0 0.1 0.5 1.3 0.1 0.0 1.1 0.1 1.2 0.0 0.1 0.2 0.0 1.1 0.5 4.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.9 170.4 55.3 4.2 8.6 2.2 1.6 3.6 0.1 1.2 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.2 0.1 0.4 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.8 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 52.3;placenta: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Cytotrophoblasts: 123.1;Hofbauer cells: 481.5;Kupffer cells: 148.8;Microglial cells: 125.5;Proximal tubular cells: 141.0;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 423.2" "Group enriched" "Detected in many" 34 "granulocytes: 423.2;monocytes: 128.4" "Cell line enhanced" "Detected in many" "HEL: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 12.7 5.8 16.7 19.2 20.8 18.9 5.5 19.3 22.9 4.3 11.1 6.9 2.8 1.7 29.9 10.0 3.3 13.0 2.6 12.7 15.6 52.3 20.8 14.5 32.5 19.6 20.1 1.4 2.8 3.3 1.7 45.2 18.9 2.3 9.1 1.9 4.2 6.2 1.7 8.4 4.4 7.5 15.8 28.7 5.0 5.1 27.0 6.2 2.6 2.8 14.7 15.5 5.1 22.0 3.4 0.6 1.0 0.0 2.8 2.8 0.9 1.1 2.1 1.2 0.6 0.0 1.4 9.0 1.5 0.0 0.0 1.3 1.9 2.4 0.3 0.0 1.5 14.2 0.4 0.1 1.5 5.4 8.1 2.2 9.1 0.2 0.0 0.1 0.1 10.1 10.9 13.8 2.1 1.1 0.3 3.5 11.0 7.0 1.1 1.4 0.7 11.0 0.2 7.4 3.1 4.6 5.0 0.3 4.7 1.1 2.9 8.7 0.2 1.1 2.4 0.7 0.1 9.8 12.7 9.0 2.4 9.5 3.6 25.5 128.4 104.1 5.5 118.2 4.8 1.8 4.5 4.9 7.6 6.3 3.5 4.9 423.2 0.3 96.6 1.5 8.1 65.4 16.7 20.8 19.3 22.9 12.7 15.6 19.6 20.1 18.9 15.8 27.0 22.0 2.9 0.0 5.5 170.1 4.9 6.1 4.0 8.6 1.8 7.6 1.5 4.4 2.9 2.8 4.8 7.3 2.1 123.1 2.2 2.3 19.6 1.2 19.1 0.4 0.6 3.5 1.8 45.5 7.5 2.4 6.1 2.5 3.1 0.2 5.7 0.5 72.8 3.9 481.5 6.7 13.5 1.4 6.1 148.8 11.5 27.0 0.9 91.7 10.6 125.5 40.1 2.8 5.2 22.1 21.0 1.3 0.3 0.4 0.7 1.6 0.9 141.0 1.7 2.8 0.0 1.7 1.7 16.5 8.9 16.5 7.1 107.4 3.1 3.4 1.6 4.3 NR1D1 "ear-1, hRev, Rev-ErbAalpha, REVERBA, REVERBalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092793-40100589 "Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 325.5" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 95.5;Suprabasal keratinocytes: 81.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.5" "Group enriched" "Detected in many" 6 "monocytes: 5.5;T-cells: 18.5" "Cell line enhanced" "Detected in all" "Karpas-707: 60.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007935 Uncertain Supported "Nuclear bodies" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies" "HPA007935: AB_10601277" "unprognostic (1.38e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.53e-1)" "unprognostic (2.24e-2)" "unprognostic (1.05e-1)" "unprognostic (4.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.93e-3)" "unprognostic (9.93e-3)" "unprognostic (2.73e-1)" "unprognostic (9.15e-3)" "unprognostic (4.54e-3)" "unprognostic (2.49e-1)" "unprognostic (3.09e-1)" "unprognostic (1.34e-1)" 72.3 53.7 23.5 6.3 27.0 5.4 63.1 52.9 49.7 109.6 10.6 53.3 14.3 35.8 4.5 42.5 27.7 7.1 60.8 24.9 17.2 38.0 43.2 49.2 9.3 18.1 20.9 71.3 24.3 9.0 32.0 6.0 15.9 40.5 4.0 50.4 52.9 16.3 99.0 325.5 23.0 7.5 12.9 11.6 31.5 12.5 34.0 6.3 32.1 38.1 5.4 42.5 96.5 25.2 5.5 7.8 1.6 6.2 9.0 6.2 2.2 11.9 19.5 3.9 4.9 5.1 19.5 6.7 6.9 13.8 12.9 15.4 4.1 18.0 2.9 5.6 4.1 4.8 7.9 13.5 14.6 7.2 6.9 13.5 12.8 13.3 28.2 12.6 4.9 7.7 7.2 60.6 3.8 3.8 10.7 6.1 3.0 10.8 12.3 7.5 2.2 20.7 5.4 4.9 5.1 2.9 7.6 9.7 12.4 2.7 4.6 5.8 4.7 17.2 16.7 14.1 9.5 21.5 35.7 2.6 23.4 4.0 13.6 0.0 0.5 0.0 4.4 2.0 18.5 1.7 5.5 6.4 1.1 2.1 4.8 3.5 0.2 1.0 5.5 1.4 8.0 1.8 23.5 27.0 52.9 49.7 24.9 17.2 18.1 20.9 15.9 12.9 34.0 25.2 16.4 3.2 2.0 17.3 5.7 64.5 47.5 20.5 67.2 71.4 9.4 15.1 5.7 8.6 11.9 1.8 4.2 2.6 4.9 26.0 7.9 16.1 2.3 25.4 30.6 18.6 8.3 3.6 7.1 11.8 1.2 26.5 31.1 64.2 2.5 2.7 6.8 31.8 2.5 42.1 6.2 7.2 8.2 3.4 19.4 1.5 21.8 7.7 19.6 8.4 1.2 39.0 5.2 5.0 1.2 26.0 14.7 38.7 10.5 35.4 58.8 7.9 5.0 29.7 6.6 9.6 19.4 2.0 11.1 95.5 81.1 2.3 11.9 13.7 6.0 28.7 NTN5 ENSG00000142233 "Netrin 5" Q8WTR8 19 48661407-48673081 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pituitary gland: 5.1" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Bipolar cells: 5.4;Early spermatids: 9.2;Horizontal cells: 8.4;Late spermatids: 11.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.2" "Region enhanced" "Detected in some" "cerebral cortex: 3.5" "Region enriched" "Detected in single" 5 "cerebellum: 4.8" "Secreted in brain" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (8.20e-3)" "unprognostic (5.54e-2)" "unprognostic (5.26e-6)" "unprognostic (4.48e-2)" "unprognostic (2.23e-1)" "unprognostic (4.33e-2)" "unprognostic (3.18e-2)" "unprognostic (1.73e-2)" "unprognostic (2.89e-3)" "unprognostic (9.40e-3)" "unprognostic (1.74e-3)" "unprognostic (4.60e-1)" "unprognostic (5.11e-2)" "unprognostic (1.60e-3)" "unprognostic (3.51e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-3)" 0.3 0.4 2.0 0.2 2.2 0.3 1.2 1.6 2.8 1.4 0.6 0.6 0.2 1.0 0.5 0.5 3.2 0.7 0.3 1.9 1.4 0.8 0.4 0.4 0.8 1.9 1.8 2.3 0.4 0.5 5.1 0.0 1.5 2.8 0.0 1.2 1.0 0.8 0.2 1.2 0.6 0.1 1.7 0.9 0.3 0.6 1.8 0.6 1.9 0.1 0.3 0.4 0.8 2.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.3 0.5 0.2 0.0 0.0 0.6 0.0 0.2 0.9 0.1 0.0 0.0 0.3 0.2 0.4 0.0 1.2 0.0 0.3 0.3 0.2 0.0 0.0 0.6 0.1 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.2 1.6 2.8 1.9 1.4 1.9 1.8 1.5 1.7 1.8 2.2 1.1 0.0 0.0 4.6 0.1 0.5 0.4 0.1 0.0 5.4 0.8 1.9 0.3 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.1 9.2 0.5 1.3 0.6 0.0 0.0 1.1 0.0 0.0 0.4 0.0 1.0 0.0 2.3 0.4 0.1 0.1 8.4 0.6 0.1 0.0 0.0 0.4 11.8 0.6 0.1 1.8 1.0 0.0 1.6 1.0 0.0 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 2.8 0.0 0.7 0.4 3.1 0.2 0.1 0.1 0.1 0.2 3.1 0.0 0.2 NXPE3 "FAM55C, MGC15606" ENSG00000144815 "Neurexophilin and PC-esterase domain family member 3" Q969Y0 3 101779202-101828231 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.2;tongue: 50.5" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 177.7;Plasma cells: 59.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 92.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036259 Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 12000 "Cluster 20: T-cells - T-cell receptor" "Cluster 80: Striated muscle - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "HPA036259: AB_10671838" "unprognostic (3.30e-1)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" "unprognostic (4.42e-5)" "unprognostic (4.98e-2)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (7.42e-2)" "unprognostic (1.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.57e-3)" "unprognostic (3.43e-1)" "prognostic unfavorable (7.76e-6)" "unprognostic (2.89e-1)" "unprognostic (5.23e-2)" "unprognostic (1.77e-1)" "unprognostic (8.75e-3)" 7.8 6.4 13.6 11.7 23.2 12.5 6.0 20.1 18.7 7.6 1.3 5.3 3.5 8.1 3.3 6.1 7.4 6.5 18.4 12.4 21.0 3.3 3.5 9.4 16.7 21.6 21.3 7.1 2.5 20.7 6.8 6.7 24.2 8.3 4.6 11.3 3.5 9.8 73.2 2.0 5.0 10.6 16.5 12.5 5.0 7.4 23.7 13.1 5.9 50.5 14.2 7.2 4.5 34.8 19.8 29.9 25.1 9.2 26.6 26.9 5.7 21.7 27.2 25.4 36.6 7.0 2.0 29.3 62.6 24.4 30.4 4.1 28.3 23.2 31.2 36.7 8.9 22.7 19.0 19.3 35.0 19.4 19.9 15.6 3.9 21.1 7.8 33.1 27.8 27.3 4.7 92.0 42.5 10.6 26.2 4.6 14.6 1.0 18.6 11.5 30.7 12.7 18.8 5.1 19.6 23.4 9.3 2.2 16.7 14.9 4.3 27.2 24.5 28.0 33.7 3.3 23.0 43.0 47.5 34.0 23.9 83.7 5.4 8.0 16.5 20.1 14.6 13.0 10.0 10.8 16.0 15.2 14.2 6.4 21.6 17.6 8.6 8.9 12.7 8.8 20.8 14.1 13.6 23.2 20.1 18.7 12.4 21.0 21.6 21.3 24.2 16.5 23.7 34.8 24.1 25.6 5.1 11.4 19.2 3.7 2.2 2.3 6.2 26.1 9.8 9.0 49.4 4.3 2.3 0.0 8.4 0.7 12.8 1.0 0.0 2.6 1.4 2.9 11.8 17.2 7.2 0.0 34.1 2.6 1.6 10.0 1.5 1.9 13.3 46.0 40.4 1.8 6.8 48.8 35.2 0.6 4.1 19.1 10.0 1.8 9.3 11.0 7.2 9.4 26.3 22.7 23.7 44.2 177.7 2.9 0.1 7.5 59.6 1.0 0.8 0.8 3.1 17.1 19.7 14.9 8.3 11.8 15.1 3.8 3.0 0.7 16.2 20.0 0.9 1.1 NXPH1 ENSG00000122584 "Neurexophilin 1" P58417 7 8433609-8752961 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "adrenal gland: 42.0;brain: 25.5" "Group enriched" "Detected in some" 40 "Inhibitory neurons: 1486.5;Oligodendrocyte precursor cells: 1500.4" "Group enriched" "Detected in some" 62 "breast cancer: 2.3;glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Karpas-707: 10.9;WM-115: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.84e-2)" "unprognostic (1.30e-1)" "unprognostic (3.74e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-2)" "unprognostic (1.46e-4)" "unprognostic (1.47e-1)" "unprognostic (3.01e-2)" "unprognostic (5.32e-1)" "unprognostic (9.46e-2)" 0.1 42.0 9.6 0.0 11.0 0.0 0.4 4.0 8.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 13.9 0.0 0.0 0.0 0.0 13.4 25.5 0.0 0.0 0.0 1.5 0.0 12.1 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 24.9 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 11.0 4.0 8.7 8.6 13.9 13.4 25.5 12.1 6.3 24.9 5.5 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1486.5 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 36.5 0.0 0.6 0.0 1500.4 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.1 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OGT "FLJ23071, HRNT1, MGC22921, O-GLCNAC, OGT1" ENSG00000147162 "O-linked N-acetylglucosamine (GlcNAc) transferase" O15294 X 71533104-71575892 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Chromatin regulator, Glycosyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030751, HPA030752, HPA030753, HPA030754, CAB034099" Approved Supported "Nucleoplasm,Plasma membrane" Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Plasma membrane" "CAB034099: AB_2157067, HPA030751: AB_10600217, HPA030752: AB_10601445, HPA030753: AB_2673594, HPA030754: AB_2673595" "unprognostic (1.37e-1)" "unprognostic (2.20e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (3.40e-2)" "prognostic favorable (1.97e-4)" "unprognostic (9.56e-3)" "unprognostic (1.96e-3)" "unprognostic (5.58e-2)" "unprognostic (2.29e-1)" "unprognostic (1.06e-1)" "unprognostic (9.74e-3)" "prognostic unfavorable (2.36e-6)" "unprognostic (2.99e-3)" "unprognostic (2.28e-1)" "unprognostic (8.03e-3)" "prognostic favorable (6.85e-7)" 59.3 55.9 39.7 38.3 42.4 61.5 62.7 43.3 51.6 72.7 40.1 62.5 30.6 56.0 62.2 52.8 76.4 26.4 55.5 43.9 35.5 61.6 45.8 70.7 71.9 36.1 35.8 85.5 102.4 24.3 46.9 26.4 37.9 75.4 39.6 36.9 64.1 27.1 62.8 68.6 86.4 24.5 36.1 122.8 67.4 19.0 36.2 57.2 70.7 39.2 57.8 55.7 67.4 44.3 40.5 37.0 47.1 41.5 49.6 45.6 31.6 30.3 54.3 32.1 49.1 39.3 45.4 47.9 20.7 37.3 33.3 49.1 52.0 29.5 39.4 41.1 53.4 30.4 98.6 28.5 37.6 62.9 48.1 43.6 59.2 35.1 65.7 55.5 30.5 100.7 31.1 160.4 31.1 34.3 48.9 75.2 31.6 35.5 49.8 47.8 52.7 62.1 50.0 45.9 24.1 21.2 46.9 30.9 30.2 35.5 22.8 42.4 35.5 34.6 27.9 36.6 17.9 43.5 33.5 56.5 24.4 65.0 21.6 2.8 4.6 2.0 7.5 5.7 6.8 7.4 6.3 6.2 6.1 6.2 7.2 7.4 1.9 10.4 5.7 6.2 6.2 5.6 39.7 42.4 43.3 51.6 43.9 35.5 36.1 35.8 37.9 36.1 36.2 44.3 31.1 35.3 85.2 52.9 67.2 88.1 37.9 23.5 58.6 26.5 49.6 34.0 42.8 20.0 31.1 49.7 8.4 15.8 130.7 31.1 9.8 14.4 2.4 32.1 49.8 39.8 34.9 51.3 110.7 14.4 8.5 47.5 54.6 53.3 27.8 26.4 45.7 27.5 16.1 40.4 94.6 37.3 22.4 60.9 69.7 4.8 53.4 45.8 35.6 71.2 51.6 11.3 51.5 92.0 97.9 17.6 34.9 29.7 147.2 53.8 34.8 15.1 28.0 21.8 32.9 44.8 42.2 2.5 6.1 63.3 84.1 10.9 82.1 62.0 34.0 50.8 OR1D2 "OLFR1, OR17-4" ENSG00000184166 "Olfactory receptor family 1 subfamily D member 2" P34982 17 3088484-3104422 "G-protein coupled receptors, Predicted membrane proteins" "Chemotaxis, Fertilization, Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9" "Cell type enriched" "Detected in single" 13 "granulocytes: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" NA NA "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 60: Granulocytes - Receptor signaling" 0.5 0.4 2.6 0.5 2.7 1.5 0.5 3.0 3.9 0.2 1.3 0.2 0.4 0.4 1.0 0.2 0.5 0.5 0.4 2.4 2.8 0.7 0.7 0.4 0.8 2.3 1.6 0.7 0.3 0.2 0.0 0.4 2.3 0.5 0.4 2.4 0.6 0.3 0.6 1.1 0.4 0.2 0.9 0.8 0.4 0.6 2.6 0.4 1.3 0.3 0.5 0.3 0.0 3.5 0.4 0.3 0.5 0.7 0.2 0.2 1.1 0.3 0.1 0.2 0.3 1.4 0.6 0.6 0.7 0.3 0.8 0.7 0.2 0.1 0.3 0.7 0.6 1.8 1.0 0.2 0.2 0.6 1.2 0.1 0.4 0.2 0.1 0.5 0.2 0.6 0.7 1.9 0.1 0.5 0.4 1.1 0.7 0.2 0.1 0.4 0.3 0.5 0.4 0.8 1.0 0.5 0.4 0.2 0.4 1.3 0.6 0.6 0.5 0.5 1.3 0.4 0.3 0.9 0.5 0.5 0.4 0.5 0.7 0.2 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.6 0.1 0.1 0.1 0.0 0.0 2.6 2.7 3.0 3.9 2.4 2.8 2.3 1.6 2.3 0.9 2.6 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 OR4C6 ENSG00000181903 "Olfactory receptor family 4 subfamily C member 6" Q8NH72 11 55662201-55666195 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 4.2;Karpas-707: 4.4" NA NA "Cluster 2: Karpas-707 - Immune response" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR6B1 OR7-3 ENSG00000221813 "Olfactory receptor family 6 subfamily B member 1" O95007 7 144000320-144008793 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.5" "Not detected" "Not detected" HPA053164 Uncertain NA NA "Cluster 2: Karpas-707 - Immune response" "HPA053164: AB_2682065" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR6C70 ENSG00000184954 "Olfactory receptor family 6 subfamily C member 70" A6NIJ9 12 55469200-55470138 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.3;Inhibitory neurons: 1.1;Oligodendrocyte precursor cells: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "Karpas-707: 2.3" NA NA "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OTUB2 "C14orf137, FLJ21916, MGC3102" ENSG00000089723 "OTU deubiquitinase, ubiquitin aldehyde binding 2" Q96DC9 14 94026340-94048930 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 7.3;testis: 14.4" "Group enriched" "Detected in many" 8 "Early spermatids: 641.1;Late spermatids: 1415.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 16.5;Karpas-707: 18.0;OE19: 18.1;RPTEC TERT1: 11.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002329, HPA075090" Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "HPA002329: AB_1079537, HPA075090: AB_2686734" "unprognostic (6.80e-3)" "unprognostic (1.39e-3)" "unprognostic (3.68e-3)" "unprognostic (4.82e-3)" "unprognostic (1.66e-1)" "unprognostic (2.20e-1)" "unprognostic (2.30e-3)" "unprognostic (1.18e-2)" "unprognostic (2.55e-1)" "unprognostic (3.09e-3)" "unprognostic (2.80e-2)" "unprognostic (1.16e-2)" "unprognostic (6.25e-3)" "unprognostic (1.15e-1)" "unprognostic (2.06e-2)" "unprognostic (1.02e-4)" "unprognostic (3.16e-1)" 0.3 0.6 1.2 0.2 1.1 0.2 0.8 1.3 1.3 1.3 0.1 0.5 0.3 0.8 0.3 3.8 0.6 0.4 0.1 1.0 0.8 0.6 0.8 0.4 0.3 0.1 1.3 0.7 0.7 1.9 0.2 1.8 0.1 0.6 0.8 0.6 0.7 0.2 0.1 7.3 0.3 0.3 0.1 0.2 0.5 14.4 2.5 0.1 0.2 0.0 0.8 0.9 1.5 0.5 1.3 3.7 2.4 2.3 0.9 0.7 2.6 0.5 0.3 1.4 2.1 0.8 5.9 0.3 2.2 0.6 16.5 0.3 3.2 1.7 1.1 0.9 1.5 0.1 0.4 3.9 1.3 0.0 0.6 0.6 2.1 0.5 0.9 1.8 1.6 3.3 0.1 18.0 0.7 1.3 0.1 0.4 0.7 18.1 3.1 0.1 0.2 1.0 11.2 1.7 1.8 1.3 0.7 0.8 1.9 1.6 6.3 0.8 1.7 0.9 2.8 0.7 1.0 3.0 2.2 0.0 1.7 0.9 1.4 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 1.2 1.1 1.3 1.3 1.0 0.8 0.1 1.3 0.1 0.1 2.5 0.5 0.5 0.0 0.5 0.7 0.2 0.1 0.7 4.0 0.6 1.5 1.1 1.1 0.5 0.0 2.4 0.0 0.0 4.2 0.1 1.9 1.9 4.3 641.1 6.4 2.8 0.9 0.0 2.7 1.9 1.6 1.5 0.6 4.6 24.8 0.0 2.2 0.4 0.9 1.4 0.0 1.3 1.4 2.0 1.2 1.3 1415.3 6.8 2.4 0.0 0.0 0.4 0.5 0.0 0.5 0.6 5.2 1.3 3.4 0.1 0.3 0.5 1.5 1.8 1.4 6.6 0.6 0.6 9.2 4.3 2.0 2.3 117.5 1.0 2.2 1.0 2.4 OTUD7B "CEZANNE, ZA20D1" ENSG00000264522 "OTU deubiquitinase 7B" Q6GQQ9 1 149937812-150010726 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 43.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Oligodendrocytes: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027045, HPA076357" Supported Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA027045: AB_1854847, HPA076357: " "unprognostic (2.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.90e-1)" "prognostic favorable (7.47e-4)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.23e-3)" "unprognostic (1.46e-2)" "prognostic favorable (5.09e-5)" "unprognostic (4.90e-2)" "unprognostic (7.72e-2)" "unprognostic (8.94e-2)" "unprognostic (3.37e-2)" "unprognostic (1.67e-2)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (1.58e-2)" 11.7 7.7 21.0 3.8 39.2 1.1 7.8 28.7 18.5 9.9 6.8 7.6 6.2 10.5 3.8 7.7 9.3 4.8 7.1 15.3 22.1 5.6 10.7 7.3 1.9 41.4 37.2 10.9 6.1 10.9 3.4 7.1 35.5 6.6 7.1 10.1 7.8 7.5 18.6 5.8 6.2 10.8 27.9 3.6 6.7 12.7 31.7 2.1 6.7 16.2 3.2 6.3 5.2 43.0 17.2 13.5 9.3 15.6 12.0 11.1 8.8 11.8 17.3 14.0 9.6 10.0 13.6 0.2 7.5 21.7 6.3 13.4 13.2 13.1 14.6 16.5 6.7 6.6 18.9 6.8 12.8 7.6 6.9 12.4 9.9 23.7 20.6 10.9 11.5 2.0 18.4 18.1 10.1 17.5 1.3 2.1 11.9 12.8 13.1 1.8 12.9 4.4 5.4 23.2 6.0 11.4 20.8 15.2 18.5 12.1 12.6 4.0 13.9 14.4 13.2 9.8 14.0 19.1 20.0 2.0 12.8 2.2 24.1 2.0 0.0 0.4 0.7 0.0 0.5 0.1 0.3 0.4 0.0 0.1 0.2 0.3 0.3 0.4 0.0 0.1 0.1 0.0 21.0 39.2 28.7 18.5 15.3 22.1 41.4 37.2 35.5 27.9 31.7 43.0 10.2 35.3 11.7 56.8 3.0 15.9 22.7 8.7 13.1 28.0 18.3 9.3 22.2 12.8 15.3 11.0 106.3 23.5 5.1 41.1 7.9 14.5 63.4 21.8 17.8 16.7 17.4 14.9 20.6 11.1 11.6 14.8 21.4 40.2 0.0 22.0 20.3 33.0 3.1 23.5 24.6 15.8 8.2 0.8 5.9 79.4 14.6 2.4 37.4 22.5 4.3 23.6 15.5 33.2 176.8 20.6 21.3 23.0 4.7 20.2 17.1 11.5 17.4 66.9 0.0 19.8 17.9 11.1 7.2 11.8 16.6 21.2 7.5 11.1 11.1 34.0 OXR1 TLDC3 ENSG00000164830 "Oxidation resistance 1" Q8N573 8 106270144-106752694 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 1458.0;Inhibitory neurons: 1366.9;Late spermatids: 405.5;Microglial cells: 496.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027375, HPA027380, HPA027395" Enhanced Approved Vesicles NA NA 12000 "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA027375: AB_10600087, HPA027380: AB_10601569, HPA027395: AB_10601554" "unprognostic (8.16e-3)" "unprognostic (1.39e-1)" "unprognostic (5.52e-2)" "unprognostic (3.12e-1)" "unprognostic (4.84e-2)" "unprognostic (2.84e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-1)" "unprognostic (2.82e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (6.59e-2)" "prognostic favorable (5.82e-5)" "unprognostic (1.89e-1)" "unprognostic (1.32e-1)" "unprognostic (2.58e-1)" "unprognostic (2.86e-1)" 28.7 57.7 19.2 11.1 27.8 18.6 29.0 14.0 50.3 30.6 0.0 20.1 14.2 27.7 54.5 28.7 22.4 22.1 30.5 25.7 4.3 29.7 38.3 20.0 14.4 19.2 6.4 27.0 17.1 23.9 12.2 17.0 21.3 21.1 21.7 79.5 48.6 47.6 52.1 27.4 12.2 21.7 1.8 19.5 27.3 56.1 10.7 22.2 21.3 59.6 16.4 23.7 17.9 22.2 29.5 11.0 32.3 6.5 41.2 51.4 15.0 23.7 28.3 21.6 27.5 9.7 35.6 29.6 26.8 25.6 13.2 20.4 18.5 21.2 37.3 24.9 20.0 39.8 15.3 18.0 25.5 12.8 22.8 30.3 32.1 23.7 34.9 30.0 24.7 24.2 20.3 106.5 24.6 26.2 38.3 17.3 4.2 43.5 19.4 9.9 25.7 55.7 24.0 36.8 19.4 6.0 10.5 7.3 25.8 14.1 34.1 21.2 18.4 24.6 17.1 22.6 15.6 19.7 13.3 12.1 29.2 3.7 30.9 38.1 9.3 17.8 3.9 17.6 6.5 11.4 6.7 6.2 11.2 7.9 16.0 7.1 4.7 11.0 19.4 7.9 5.2 7.8 19.2 27.8 14.0 50.3 25.7 4.3 19.2 6.4 21.3 1.8 10.7 22.2 54.9 67.3 25.5 125.0 47.1 67.6 57.2 42.6 60.9 89.8 36.7 33.5 58.2 15.7 37.3 35.0 58.4 32.6 44.1 44.3 33.2 16.6 231.2 75.3 32.1 41.8 27.5 19.5 1458.0 17.0 20.0 41.3 39.8 65.3 30.4 29.1 44.6 34.5 19.5 26.9 1366.9 28.2 34.6 33.0 41.4 405.5 34.2 36.3 24.9 496.5 41.1 55.6 22.6 294.0 142.6 23.6 24.9 48.9 73.7 60.4 16.5 16.4 53.5 125.8 19.7 46.4 41.6 140.4 51.6 56.7 75.6 71.1 26.5 33.5 26.4 86.1 P2RY10 P2Y10 ENSG00000078589 "P2Y receptor family member 10" O00398 X 78945332-78963727 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4" "Cell type enhanced" "Detected in some" "B-cells: 79.3;granulocytes: 29.2;Langerhans cells: 38.5;monocytes: 32.5;Plasma cells: 32.6;T-cells: 55.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "basophil: 256.1" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "Karpas-707: 121.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036757, HPA065766" Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA036757: AB_10696786, HPA065766: AB_2685556" "unprognostic (3.02e-3)" "unprognostic (1.47e-3)" "unprognostic (1.50e-6)" "unprognostic (6.62e-3)" "unprognostic (1.19e-1)" "unprognostic (1.13e-4)" "unprognostic (3.33e-2)" "unprognostic (8.30e-2)" "unprognostic (1.13e-2)" "unprognostic (4.13e-3)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (2.23e-1)" "unprognostic (6.54e-2)" "unprognostic (3.85e-2)" "unprognostic (3.99e-2)" 0.8 0.5 0.4 14.6 0.5 8.2 0.9 1.4 1.1 1.0 0.0 2.7 3.1 0.8 0.3 1.1 0.4 3.2 0.4 0.4 0.1 0.4 1.6 2.4 27.4 0.2 0.0 0.4 1.5 0.0 0.1 0.3 0.2 1.3 3.6 0.6 1.2 0.2 0.2 0.6 6.4 0.7 0.0 16.6 3.9 0.3 0.2 10.3 0.6 0.1 25.8 5.4 0.4 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 14.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.3 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 121.8 0.0 0.1 0.2 0.2 0.2 0.0 0.2 0.2 0.2 9.9 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.2 0.1 0.0 26.5 0.1 1.4 0.2 0.3 0.1 256.1 0.2 158.1 12.6 0.9 11.4 73.1 28.0 25.5 4.0 74.1 25.7 19.5 27.9 18.1 10.9 2.8 41.7 13.2 0.4 0.5 1.4 1.1 0.4 0.1 0.2 0.0 0.2 0.0 0.2 0.5 0.7 0.0 1.7 0.0 79.3 1.8 0.0 0.0 0.0 0.0 0.3 0.3 1.2 0.0 0.6 0.0 0.0 0.0 15.0 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.4 0.0 0.8 0.5 0.1 29.2 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.6 38.5 0.0 0.0 3.6 8.8 0.0 32.5 0.0 9.2 0.0 0.0 0.0 0.0 0.0 32.6 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 2.0 0.0 55.1 0.0 0.0 0.3 PAPSS1 "ATPSK1, PAPSS" ENSG00000138801 "3'-phosphoadenosine 5'-phosphosulfate synthase 1" O43252 4 107590276-107720234 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 444.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 321.8;eosinophil: 359.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 359.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049781 Approved Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No 13000 "Cluster 2: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA049781: AB_2680879" "unprognostic (1.36e-2)" "unprognostic (5.03e-2)" "prognostic favorable (9.14e-4)" "prognostic favorable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.70e-5)" "unprognostic (1.58e-2)" "unprognostic (1.05e-1)" "unprognostic (8.92e-2)" "unprognostic (1.42e-1)" "unprognostic (5.76e-2)" "unprognostic (6.23e-3)" "unprognostic (1.29e-1)" "unprognostic (1.72e-1)" "unprognostic (1.61e-2)" "unprognostic (1.38e-1)" 26.3 14.2 36.8 30.8 43.9 26.0 49.9 46.4 50.0 49.6 26.5 20.4 16.0 47.1 43.0 36.2 48.4 26.4 15.9 41.9 40.8 31.7 10.3 44.4 32.9 53.2 41.4 29.2 49.3 26.9 15.8 17.2 51.8 41.1 24.7 22.3 66.0 25.9 6.1 49.7 15.8 33.6 51.1 17.4 62.8 17.0 41.8 35.4 20.3 9.9 51.7 31.7 23.7 66.3 33.6 29.7 49.1 62.1 59.1 74.0 39.6 42.4 77.2 39.4 53.1 45.7 46.7 51.3 26.0 76.1 30.4 40.7 46.8 81.6 50.5 124.2 35.5 60.4 62.6 103.0 32.3 93.0 99.8 61.7 41.2 45.7 37.1 95.2 88.7 63.9 13.6 97.0 111.6 50.7 77.3 28.2 52.6 35.3 33.1 62.4 78.0 15.0 59.6 45.6 55.5 81.4 42.9 63.3 51.9 61.9 37.9 14.1 52.9 49.3 51.0 33.6 35.4 76.9 57.2 48.7 60.1 69.3 79.2 321.8 49.9 359.8 15.6 56.2 18.8 44.8 21.2 18.0 51.4 26.4 13.2 14.9 55.5 27.6 60.8 9.8 39.9 36.7 36.8 43.9 46.4 50.0 41.9 40.8 53.2 41.4 51.8 51.1 41.8 66.3 19.7 96.1 20.2 41.4 25.4 32.0 36.3 73.2 33.6 19.9 48.4 41.5 7.4 50.1 92.3 57.0 10.4 20.6 7.0 10.5 17.6 36.8 6.2 124.2 84.6 25.1 23.4 15.3 112.2 44.7 48.7 35.2 62.2 444.3 42.5 25.0 20.3 10.2 55.1 30.3 64.7 17.5 32.6 46.5 27.8 6.7 18.0 53.5 60.5 29.0 37.4 35.0 10.3 100.0 150.3 33.6 9.1 25.6 86.4 29.1 6.9 28.8 110.0 13.3 26.3 45.2 29.1 19.6 14.7 62.9 40.9 8.9 22.2 19.2 14.8 29.4 PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.9;Distal enterocytes: 398.3;Intestinal goblet cells: 109.7;Paneth cells: 132.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 15 "B-cells: 8.1;dendritic cells: 4.0" "Cell line enhanced" "Detected in many" "ASC diff: 44.6;Karpas-707: 44.9;U-266/70: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" 45.1 51.8 4.1 27.7 5.4 0.4 29.3 0.0 19.3 43.3 2.1 91.3 7.0 34.7 14.0 13.5 23.3 28.6 103.6 10.4 26.0 55.9 1.3 33.7 18.2 1.3 3.9 19.6 34.1 73.1 41.0 40.7 21.2 83.8 113.4 6.0 39.4 64.5 21.0 11.1 15.7 48.2 0.0 15.3 13.4 12.0 4.1 17.3 123.7 18.1 20.9 44.9 25.0 0.0 1.1 1.9 1.7 0.0 44.6 0.3 0.2 0.0 0.2 0.0 0.0 3.9 0.3 0.0 0.2 0.0 0.1 0.1 15.1 0.0 0.0 0.2 3.3 0.0 0.0 0.0 7.4 0.0 1.3 1.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 44.9 0.8 0.5 5.2 0.2 4.3 0.0 2.7 0.0 4.1 11.8 0.2 9.5 2.8 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.0 2.7 2.9 0.3 4.2 49.8 5.1 12.9 4.7 0.0 0.7 0.0 0.1 0.0 0.0 0.3 0.0 8.1 0.0 0.0 4.0 5.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.5 4.1 5.4 0.0 19.3 10.4 26.0 1.3 3.9 21.2 0.0 4.1 0.0 44.8 16.0 84.1 2.9 11.6 3.2 27.2 6.5 4.0 7.0 4.0 3.4 181.9 31.5 10.4 0.0 0.0 0.3 0.1 398.3 3.9 0.5 10.1 3.0 73.5 6.4 19.9 2.7 51.3 49.2 0.7 13.2 2.0 2.8 1.3 61.9 2.9 0.0 1.5 0.0 77.8 109.7 14.2 0.3 34.7 28.6 36.7 4.9 8.8 1.0 0.7 0.1 0.0 6.0 3.6 23.5 132.1 74.4 42.9 32.6 2.5 27.7 7.2 1.7 46.0 5.4 61.5 1.6 3.2 0.3 1.8 0.8 1.9 14.9 81.6 9.1 PBXIP1 HPIP ENSG00000163346 "PBX homeobox interacting protein 1" Q96AQ6 1 154944076-154956123 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 176.0;Muller glia cells: 221.4;Theca cells: 153.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 183.9;NK-cells: 56.9;T-cells: 197.4" "Cell line enriched" "Detected in all" 7 "Karpas-707: 1100.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006949 Approved Approved Vesicles,Cytosol NA NA 26000 "Cluster 13: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Vesicles Cytosol "HPA006949: AB_1079572" "unprognostic (6.17e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (8.94e-2)" "unprognostic (2.16e-1)" "prognostic favorable (7.19e-4)" "unprognostic (1.62e-1)" "prognostic favorable (8.99e-4)" "unprognostic (1.21e-1)" "unprognostic (2.46e-1)" "prognostic favorable (2.64e-4)" "unprognostic (1.20e-2)" "prognostic favorable (9.22e-6)" "unprognostic (3.89e-1)" "unprognostic (4.15e-1)" "unprognostic (2.26e-1)" "unprognostic (1.26e-3)" 57.7 122.5 169.3 58.4 180.3 35.1 45.9 159.8 158.8 74.5 296.1 124.5 55.4 81.7 39.0 46.0 68.8 52.8 67.7 144.4 173.6 56.9 29.7 49.0 69.4 208.2 189.7 115.3 34.0 102.4 168.9 33.3 168.5 63.6 29.7 38.9 53.0 95.3 139.7 37.2 90.7 52.4 171.7 82.2 82.7 58.1 210.4 80.8 85.9 100.5 59.1 79.2 50.5 161.2 7.3 19.1 29.9 20.0 101.3 31.5 22.0 25.1 55.3 11.9 23.5 5.6 24.9 31.3 79.1 30.5 17.0 26.8 7.3 16.1 8.3 16.9 11.7 7.1 26.2 20.1 46.9 8.6 83.6 48.0 26.2 15.1 3.0 137.7 45.4 23.6 4.2 1100.7 29.8 11.1 17.6 27.5 11.4 19.3 14.4 20.2 43.1 69.7 32.9 14.1 4.9 37.6 32.5 10.2 26.7 56.1 31.0 36.6 42.9 11.8 8.6 7.6 7.8 149.4 133.9 7.7 42.2 12.4 9.6 129.4 10.3 183.9 41.9 14.8 116.3 36.0 112.4 66.9 9.1 23.6 72.9 46.2 95.2 56.9 29.7 16.2 197.4 61.5 169.3 180.3 159.8 158.8 144.4 173.6 208.2 189.7 168.5 171.7 210.4 161.2 24.5 67.3 77.9 56.8 43.0 10.1 24.0 22.4 13.1 23.8 17.6 19.7 38.5 38.6 31.1 42.3 16.7 19.5 48.2 21.0 0.0 46.0 142.1 12.9 25.9 23.8 83.7 22.3 1.5 18.5 24.0 35.9 19.9 10.5 51.9 30.3 28.9 19.4 14.7 1.7 1.2 20.9 69.2 20.2 13.8 176.0 64.3 16.8 26.6 7.5 25.5 221.4 39.1 3.5 1.6 22.4 29.3 129.1 49.0 10.5 56.0 9.9 23.9 8.8 52.6 83.9 50.6 8.8 13.9 6.3 11.5 27.1 116.2 153.3 15.9 13.9 PCBP2 "hnRNP-E2, HNRNPE2, HNRPE2" ENSG00000197111 "Poly(rC) binding protein 2" Q15366 12 53452102-53481162 "Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Viral RNA replication" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038356, HPA073145" Approved Supported Nucleoplasm,Cytosol NA NA 970000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA038356: AB_10697248, HPA073145: " "unprognostic (1.44e-1)" "unprognostic (2.08e-1)" "unprognostic (9.89e-2)" "unprognostic (2.92e-3)" "unprognostic (4.34e-3)" "unprognostic (2.69e-2)" "prognostic unfavorable (1.82e-5)" "unprognostic (2.52e-1)" "unprognostic (2.05e-2)" "prognostic favorable (8.23e-4)" "unprognostic (3.53e-2)" "unprognostic (2.12e-1)" "unprognostic (2.04e-1)" "unprognostic (9.84e-2)" "unprognostic (3.35e-1)" "unprognostic (1.99e-1)" "unprognostic (8.20e-2)" 467.6 429.4 213.6 263.0 232.5 863.1 396.1 260.1 240.3 385.9 238.8 318.2 334.8 345.0 366.4 314.4 407.8 301.5 340.3 197.9 232.9 534.9 509.0 350.9 380.4 228.2 223.5 507.3 501.5 437.3 220.7 299.7 232.8 265.5 325.5 665.2 322.1 264.5 481.1 416.6 324.5 333.8 227.4 323.8 390.4 363.6 228.8 543.6 414.9 401.7 455.6 313.3 323.5 263.2 527.6 809.2 755.8 614.7 1068.5 809.3 582.3 547.0 722.3 844.6 605.4 951.9 760.5 916.9 518.6 796.7 398.6 501.2 830.1 720.1 830.0 579.1 617.4 917.3 597.0 946.0 1071.1 922.5 592.1 937.8 593.9 719.6 1147.1 1451.3 819.3 583.5 810.8 1621.9 762.9 1444.3 856.8 1030.1 975.1 447.8 559.7 690.0 686.4 1098.4 667.5 814.6 742.4 655.6 736.2 656.2 553.9 767.2 918.2 791.8 615.9 443.9 614.0 412.7 561.7 908.2 666.0 840.7 523.9 572.6 494.4 19.1 34.5 25.9 27.7 34.0 44.6 38.1 42.3 35.7 41.6 34.3 48.1 41.8 30.8 23.9 33.3 57.2 52.3 30.1 213.6 232.5 260.1 240.3 197.9 232.9 228.2 223.5 232.8 227.4 228.8 263.2 306.1 115.4 179.2 64.9 433.6 390.7 302.9 352.6 569.1 88.0 361.5 389.9 73.7 253.1 193.0 296.1 110.5 329.2 313.6 242.9 493.1 233.0 68.3 264.2 289.3 285.1 206.5 525.1 54.6 240.0 365.1 285.8 326.2 298.1 155.0 360.3 283.4 302.2 368.2 102.6 58.1 279.1 223.8 437.6 473.8 65.6 309.1 376.0 233.1 74.0 476.5 152.9 292.5 58.8 101.4 250.8 266.5 229.0 483.8 256.3 446.8 714.4 159.5 188.3 190.7 346.6 435.1 292.8 183.4 511.3 382.3 443.3 341.6 240.4 325.7 345.0 PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 4 "Adipocytes: 38.5;Endothelial cells: 40.0;Hepatic stellate cells: 41.0;Hofbauer cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 25.9;Karpas-707: 66.5;U-937: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" 13.4 5.0 0.8 2.5 0.9 0.5 4.9 2.5 1.7 2.7 1.2 2.0 2.0 2.8 0.4 2.1 2.1 4.0 10.8 0.6 0.8 6.0 4.0 15.5 2.6 0.5 0.3 1.7 1.4 2.9 3.6 30.2 0.6 1.9 1.3 1.6 1.4 2.3 4.0 1.7 2.1 5.2 0.3 18.6 2.0 1.1 1.4 0.8 6.5 5.1 1.0 3.2 1.9 0.3 0.1 0.1 1.9 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 5.0 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.6 1.4 0.2 0.1 0.2 0.5 0.2 0.0 0.0 0.4 0.0 0.4 25.9 0.3 0.0 66.5 0.0 0.4 0.1 0.3 0.5 0.0 0.3 0.5 0.2 3.0 0.0 0.1 0.3 0.7 0.1 0.1 0.3 0.2 0.0 1.8 1.8 0.6 0.1 0.9 0.1 0.4 0.4 0.1 0.4 11.7 2.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.8 0.9 2.5 1.7 0.6 0.8 0.5 0.3 0.6 0.3 1.4 0.3 38.5 0.0 1.1 0.0 0.5 0.6 0.0 0.0 1.2 1.3 0.1 0.1 4.0 0.0 0.0 0.0 2.1 0.3 0.3 0.0 3.9 0.1 1.7 0.1 0.1 40.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.1 1.3 0.0 41.0 0.5 34.6 0.0 0.2 0.0 0.0 8.5 0.3 2.5 0.0 1.5 1.8 6.5 0.3 0.5 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.2 0.3 0.5 0.2 1.4 0.0 0.2 PCMTD1 FLJ10883 ENSG00000168300 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1" Q96MG8 8 51817575-51899186 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025696, HPA061444" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA025696: AB_1855077, HPA061444: AB_2684519" "unprognostic (3.16e-2)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (2.79e-1)" "unprognostic (1.41e-1)" "unprognostic (6.73e-3)" "unprognostic (2.58e-2)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.66e-1)" "unprognostic (2.18e-2)" "unprognostic (8.38e-2)" "unprognostic (3.73e-1)" "unprognostic (2.48e-2)" "unprognostic (1.13e-1)" "unprognostic (3.11e-3)" "unprognostic (3.11e-3)" 36.5 35.2 18.2 23.3 20.2 16.8 38.2 25.2 21.9 33.8 23.2 38.8 25.9 35.3 47.5 28.0 30.8 29.0 35.5 16.4 19.9 38.3 30.4 28.3 28.8 19.1 19.2 42.6 73.9 77.9 25.5 26.3 19.9 36.1 25.8 25.4 57.6 32.0 83.4 33.5 26.8 28.3 18.9 46.3 29.5 14.9 18.9 35.1 53.3 67.1 27.3 32.6 31.0 21.6 11.7 5.7 24.3 5.4 34.1 28.4 14.0 13.4 22.8 5.5 9.0 3.1 23.6 12.0 18.0 17.3 8.4 27.2 4.7 15.8 9.3 11.9 8.5 12.6 11.7 8.3 43.9 5.2 12.4 30.4 31.7 6.9 17.4 35.8 24.4 16.0 9.5 36.0 12.0 4.2 24.5 13.7 8.9 16.7 3.0 8.0 4.5 13.8 24.7 21.7 16.2 15.0 10.9 14.8 17.1 18.5 14.2 7.6 22.2 6.8 5.9 8.8 5.2 21.6 15.6 3.9 16.4 11.4 7.0 18.7 8.4 23.2 8.6 11.0 10.4 13.1 11.5 9.4 8.1 13.0 13.5 12.4 29.4 21.6 12.7 14.7 13.2 9.1 18.2 20.2 25.2 21.9 16.4 19.9 19.1 19.2 19.9 18.9 18.9 21.6 98.4 115.4 68.1 78.7 78.1 54.0 66.0 49.7 58.6 80.7 66.7 61.0 92.7 48.6 52.0 84.6 10.4 38.1 80.7 28.7 64.6 32.9 4.7 66.6 63.9 79.3 46.7 51.4 144.7 39.8 37.2 79.2 45.9 92.2 53.0 107.2 76.4 37.1 25.1 58.9 159.7 39.0 61.1 51.8 56.8 10.4 104.1 62.7 71.2 144.3 52.5 120.8 55.6 106.1 122.3 43.8 32.2 120.0 101.8 98.0 45.5 92.8 56.7 24.0 39.5 73.2 68.2 16.4 24.2 38.3 59.2 68.5 62.1 87.6 30.9 94.6 PHF21A "BHC80, BM-006, KIAA1696" ENSG00000135365 "PHD finger protein 21A" Q96BD5 11 45929319-46121454 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 172.4;Excitatory neurons: 171.0;Inhibitory neurons: 140.0;Microglial cells: 138.7;Oligodendrocyte precursor cells: 250.3;Oligodendrocytes: 231.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 34.9;neutrophil: 31.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 34.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023253, HPA023580" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA023253: , HPA023580: AB_10962727" "unprognostic (5.30e-3)" "unprognostic (8.93e-2)" "prognostic unfavorable (6.15e-4)" "unprognostic (1.93e-2)" "unprognostic (1.05e-1)" "unprognostic (2.44e-2)" "prognostic unfavorable (1.66e-6)" "unprognostic (2.20e-2)" "unprognostic (3.10e-1)" "unprognostic (5.35e-2)" "unprognostic (1.25e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (2.59e-8)" "unprognostic (1.89e-1)" "unprognostic (1.97e-1)" "unprognostic (9.53e-2)" "unprognostic (1.21e-1)" 13.1 17.4 18.5 20.5 25.1 28.8 11.0 39.1 23.8 12.9 5.4 18.5 7.0 17.2 10.7 11.4 12.9 12.6 17.4 13.2 20.7 7.9 8.0 17.3 16.8 17.0 17.9 24.1 8.6 16.5 12.8 13.1 15.8 12.1 9.5 16.7 9.9 11.3 15.3 13.5 10.4 16.7 12.0 17.4 10.0 23.7 26.8 17.8 12.8 12.8 14.8 14.0 11.6 27.3 7.3 19.1 36.8 35.6 14.8 22.5 4.9 14.6 25.4 12.3 20.5 3.7 11.2 30.4 10.3 14.2 19.3 8.2 22.0 9.4 12.4 34.0 15.3 17.2 19.9 7.7 17.6 12.5 25.9 20.6 21.3 7.1 20.2 30.2 18.4 21.1 21.0 48.2 14.5 6.9 13.6 20.6 31.9 9.3 11.3 22.8 18.2 10.4 12.6 12.2 24.1 31.7 21.6 10.9 16.0 23.6 19.7 23.5 18.8 20.2 16.3 16.9 12.0 52.5 46.2 20.8 16.1 13.6 16.3 34.9 7.8 4.1 6.1 3.9 5.1 5.0 4.7 5.4 4.3 4.2 2.8 4.8 31.3 5.6 7.2 2.9 6.0 4.1 18.5 25.1 39.1 23.8 13.2 20.7 17.0 17.9 15.8 12.0 26.8 27.3 13.9 12.8 17.7 172.4 25.2 10.3 8.8 11.2 22.2 25.5 11.8 12.1 25.7 10.0 10.5 3.7 27.1 4.3 26.1 4.8 1.9 10.0 9.0 10.3 26.8 15.0 23.4 18.7 171.0 6.3 3.4 18.3 12.8 11.1 16.5 30.1 12.5 5.5 10.0 15.2 140.0 6.8 4.1 25.4 12.4 8.2 26.1 23.9 10.6 138.7 35.6 7.9 37.0 250.3 231.3 5.5 6.5 14.7 21.8 7.6 5.6 3.9 15.4 23.3 13.1 18.6 18.8 16.9 16.9 19.0 8.8 4.2 19.5 19.2 6.2 5.7 PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960768-49964072 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 408.4;Syncytiotrophoblasts: 389.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 20.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 163.3;SK-BR-3: 144.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA068758: AB_2686026" "unprognostic (3.67e-2)" "unprognostic (7.69e-3)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.09e-4)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (3.92e-3)" "unprognostic (7.27e-3)" 97.8 48.4 25.9 31.3 31.3 114.3 80.2 32.8 38.1 49.2 26.9 55.1 23.8 40.8 12.7 80.8 54.0 25.8 68.7 25.2 32.6 113.3 92.9 107.1 28.2 40.6 36.1 35.7 73.1 21.6 51.3 21.3 38.0 87.3 10.4 3.1 93.5 22.6 112.0 116.4 51.6 9.9 30.3 80.7 118.1 33.9 35.2 19.0 54.9 35.0 13.0 71.0 68.6 39.9 26.8 17.7 11.6 21.9 9.0 6.7 65.5 16.5 26.7 19.4 14.0 29.5 22.3 47.3 20.1 4.6 39.1 22.5 22.3 12.6 6.9 35.8 92.1 19.5 46.3 36.0 41.8 42.5 36.0 12.8 41.0 11.9 20.2 10.5 63.5 31.7 27.0 163.3 5.9 60.6 21.7 76.4 24.2 28.1 27.8 100.3 19.2 57.6 10.6 20.3 41.1 28.6 32.2 144.7 109.2 10.7 19.0 56.4 16.8 12.1 51.5 19.8 27.1 82.2 56.9 41.4 30.1 24.1 33.2 0.0 4.0 0.1 2.2 4.1 2.5 4.3 5.0 4.4 3.1 7.5 4.8 1.9 20.7 1.7 5.2 7.0 5.8 2.7 25.9 31.3 32.8 38.1 25.2 32.6 40.6 36.1 38.0 30.3 35.2 39.9 120.2 64.1 85.9 6.5 107.7 227.3 236.8 79.1 96.8 31.5 99.2 67.3 32.8 121.5 72.8 80.9 2.1 56.9 79.5 57.9 84.1 50.9 5.1 114.2 76.3 167.7 97.7 10.8 10.2 54.5 346.5 69.0 202.3 170.5 69.3 16.8 98.6 45.9 69.7 62.2 6.7 101.7 81.4 41.1 408.4 4.8 32.3 134.8 108.5 6.5 35.8 14.0 11.3 6.6 20.5 71.0 94.6 11.3 95.1 298.4 58.1 88.5 40.9 16.5 26.3 39.4 57.3 26.1 37.7 95.3 204.7 389.9 90.4 11.6 79.0 266.0 PIP4K2A "PIP5K2A, PIP5KIIA, PIP5KIIalpha" ENSG00000150867 "Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha" P48426 10 22534854-22714578 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 498.1" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1585.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065440, HPA068771" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 4900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Plasma membrane, Cytosol" "HPA065440: AB_2685490, HPA068771: AB_2686030" "unprognostic (1.11e-1)" "unprognostic (2.71e-3)" "unprognostic (1.57e-3)" "unprognostic (4.20e-3)" "unprognostic (1.55e-1)" "unprognostic (8.80e-3)" "unprognostic (1.56e-3)" "unprognostic (7.32e-2)" "unprognostic (1.68e-1)" "unprognostic (7.08e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.46e-4)" "unprognostic (1.52e-3)" "unprognostic (2.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.92e-3)" 28.4 15.5 162.5 47.8 329.4 44.8 15.0 239.0 239.9 26.5 49.8 17.8 13.2 21.1 11.8 19.8 15.2 32.9 13.5 169.7 193.6 16.5 18.6 25.9 81.2 260.6 273.4 8.8 10.9 24.8 8.5 23.7 271.7 9.3 19.1 15.3 7.8 13.0 5.1 8.3 20.6 31.5 171.8 62.6 19.3 12.5 233.3 60.4 12.8 10.9 88.5 24.1 10.5 498.1 30.2 29.2 33.4 10.8 52.3 70.6 25.3 55.0 58.1 29.1 35.7 27.6 47.2 63.2 19.4 111.0 63.7 10.4 29.2 15.4 29.2 140.5 30.4 118.7 21.6 60.9 92.5 23.1 89.1 35.6 13.7 39.7 38.2 44.6 43.7 83.5 67.4 119.1 54.5 12.5 92.3 20.5 13.7 14.5 20.7 36.9 47.8 86.3 43.0 5.8 6.1 13.9 17.7 9.0 86.4 37.6 7.6 39.1 53.0 22.3 32.8 41.7 33.9 75.1 46.3 45.0 60.5 68.3 17.6 72.6 32.6 104.0 119.5 57.9 164.0 52.1 94.2 139.9 43.7 33.1 62.8 118.2 40.5 144.2 67.3 44.8 75.9 183.4 162.5 329.4 239.0 239.9 169.7 193.6 260.6 273.4 271.7 171.8 233.3 498.1 22.5 3.2 6.7 84.9 43.2 17.6 4.0 2.0 3.4 5.7 12.9 5.5 8.1 14.3 5.6 18.4 2.1 8.6 196.9 3.4 11.7 9.7 22.9 7.4 15.7 29.2 4.9 236.9 65.6 10.7 5.4 19.6 6.6 24.8 22.8 13.4 62.4 8.7 31.8 13.5 62.0 2.9 0.0 98.6 80.0 34.5 16.8 82.8 104.9 142.4 81.3 5.0 159.6 167.9 1585.0 22.1 3.7 10.1 36.4 7.1 1.0 15.6 2.2 9.1 19.7 14.1 30.6 6.1 7.9 3.3 16.9 12.4 130.7 8.5 2.8 6.6 PIP5KL1 "bA203J24.5, MGC46424" ENSG00000167103 "Phosphatidylinositol-4-phosphate 5-kinase like 1" Q5T9C9 9 127920881-127930785 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 22.6;Late spermatids: 24.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Karpas-707: 45.5;RPMI-8226: 31.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA056240 Uncertain Supported Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA056240: AB_2683075" "unprognostic (2.15e-2)" "unprognostic (3.06e-1)" "unprognostic (1.23e-3)" "unprognostic (8.51e-5)" "unprognostic (1.44e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-1)" "unprognostic (6.29e-2)" "unprognostic (5.20e-2)" "unprognostic (5.50e-2)" "unprognostic (2.49e-2)" "unprognostic (1.57e-3)" "unprognostic (9.95e-8)" "unprognostic (1.87e-1)" "unprognostic (7.21e-2)" "unprognostic (6.05e-2)" "unprognostic (1.59e-1)" 0.6 0.2 1.0 0.0 1.0 0.6 1.7 1.6 1.8 2.3 0.2 1.0 0.1 1.3 0.2 3.2 1.7 0.3 0.2 0.9 1.0 1.3 0.2 1.9 0.1 2.1 0.8 0.9 1.3 2.9 3.8 0.6 2.4 3.1 0.0 0.2 3.2 1.4 0.1 3.9 0.5 0.3 0.7 0.6 1.4 2.5 1.3 0.1 1.7 0.0 0.2 1.0 3.6 1.0 0.0 0.7 0.7 0.8 0.8 1.9 4.1 0.8 0.8 0.2 0.2 0.3 5.5 0.5 1.6 3.7 1.6 1.7 0.0 4.1 0.2 0.3 2.7 0.0 1.4 0.1 1.3 0.0 0.2 2.1 2.6 0.6 0.0 1.3 0.0 3.7 0.0 45.5 0.0 4.0 0.0 1.6 0.4 1.7 0.6 0.4 0.1 31.5 0.0 0.1 1.4 2.7 0.3 1.0 0.0 0.4 1.7 2.2 0.6 0.5 1.3 0.9 0.1 4.0 2.8 1.0 8.0 0.6 0.5 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 1.0 1.6 1.8 0.9 1.0 2.1 0.8 2.4 0.7 1.3 1.0 0.5 0.0 9.3 0.3 1.1 2.2 4.7 5.1 8.6 0.7 3.2 4.7 0.5 0.0 2.0 5.5 0.0 0.9 1.5 0.6 1.9 1.4 22.6 2.3 3.5 0.8 0.0 3.2 0.9 1.5 4.4 0.9 7.7 4.1 0.0 1.7 0.4 0.3 0.3 5.0 1.7 0.4 2.0 0.3 0.6 24.6 0.9 0.3 0.0 0.0 0.2 1.9 0.0 0.0 0.1 1.2 0.1 0.4 2.0 2.9 0.1 0.1 7.4 0.8 0.0 1.0 1.3 1.8 2.2 2.3 1.1 3.1 0.9 1.2 0.7 2.1 PLCL1 "PLC-L, PLCE, PLCL, PPP1R127, PRIP" ENSG00000115896 "Phospholipase C like 1 (inactive)" Q15111 2 197804593-198572581 "Metabolic proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.3;tongue: 40.8" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 2062.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 6 "T-cells: 1.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.7;K-562: 15.6;Karpas-707: 10.7;MOLT-4: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031849 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA031849: AB_10602192" "unprognostic (7.77e-3)" "unprognostic (2.57e-1)" "unprognostic (2.09e-1)" "unprognostic (5.18e-3)" "unprognostic (4.40e-2)" "unprognostic (7.14e-2)" "unprognostic (2.05e-1)" "unprognostic (4.42e-3)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" "unprognostic (3.02e-2)" "unprognostic (7.42e-2)" "prognostic favorable (3.91e-7)" "unprognostic (1.07e-4)" "unprognostic (6.74e-2)" "unprognostic (1.68e-1)" "unprognostic (3.20e-2)" 4.0 4.1 15.6 2.7 40.5 1.6 2.4 32.5 21.4 4.5 9.5 4.0 0.6 14.8 3.1 3.6 3.3 3.0 32.4 13.8 30.8 31.5 0.5 3.2 3.4 42.6 37.4 7.0 1.6 14.8 2.1 7.9 39.2 10.5 1.3 4.0 2.3 7.1 30.8 0.9 1.8 6.0 22.6 1.9 2.2 1.7 27.7 17.2 3.3 40.8 2.6 4.1 1.9 65.3 0.0 0.0 0.1 0.0 1.6 0.4 0.0 0.4 0.2 0.1 0.1 0.0 0.1 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 1.5 0.0 0.2 0.0 1.8 4.2 0.0 0.0 0.0 0.0 8.7 2.9 15.6 10.7 0.1 0.4 11.4 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.2 0.0 1.6 0.9 1.8 0.0 2.5 0.8 0.2 0.0 0.7 0.2 0.0 0.0 0.1 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 1.4 0.0 15.6 40.5 32.5 21.4 13.8 30.8 42.6 37.4 39.2 22.6 27.7 65.3 7.0 19.2 4.4 44.4 0.9 1.3 0.8 0.0 0.6 14.8 2.0 1.8 159.0 1.5 1.9 14.7 0.0 0.1 0.8 1.8 58.7 0.9 15.5 2.0 102.7 5.4 1.8 0.0 201.0 0.4 0.0 6.0 1.1 1.9 6.3 3.8 0.4 0.0 3.1 15.2 160.9 0.0 2.0 4.1 2.0 3.8 1.8 4.6 0.0 49.6 2.9 2.7 0.0 181.5 2062.6 0.2 0.0 7.9 3.8 0.6 0.6 52.4 2.2 1.2 32.9 5.4 31.8 1.0 1.8 0.2 1.3 0.1 8.2 1.6 0.1 0.3 PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.2" "Cell type enhanced" "Detected in many" "Adipocytes: 91.2;Astrocytes: 98.6;Endothelial cells: 58.4;Microglial cells: 131.2;Oligodendrocytes: 168.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "memory B-cell: 23.9;naive B-cell: 22.9" "Lineage enriched" "Detected in single" 31 "B-cells: 23.9" "Cell line enhanced" "Detected in many" "AF22: 17.6;HAP1: 26.4;Karpas-707: 23.4;U-698: 16.6" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA027128: AB_2672124, HPA027319: AB_10600306, HPA028270: AB_10611388" "unprognostic (2.93e-1)" "unprognostic (3.44e-1)" "unprognostic (3.04e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-3)" "unprognostic (3.63e-1)" "unprognostic (4.30e-2)" "unprognostic (3.83e-1)" "unprognostic (2.15e-2)" 15.1 1.6 9.8 9.4 12.3 2.4 13.7 15.5 8.9 7.5 3.9 5.9 4.9 5.6 10.8 9.4 8.7 7.9 6.9 5.8 8.7 7.7 4.9 10.4 14.7 19.5 16.2 3.1 2.7 6.7 3.6 14.2 18.3 2.7 5.9 4.7 3.5 4.9 3.5 7.4 6.6 5.6 18.2 31.2 4.5 6.3 19.1 22.4 5.7 5.0 13.9 9.1 5.3 21.5 0.0 0.2 17.6 0.1 0.0 0.0 12.6 0.0 0.0 0.0 0.0 10.1 4.4 7.2 6.8 0.0 1.6 2.5 26.4 2.4 0.0 11.4 2.9 0.4 1.4 0.0 0.0 0.0 1.9 1.1 6.7 0.0 0.2 0.0 11.0 5.9 0.0 23.4 0.0 0.3 2.3 0.1 1.3 7.0 0.7 1.2 0.0 0.0 5.1 11.9 0.5 0.1 0.1 3.1 2.2 1.9 0.0 0.1 11.2 0.1 2.4 0.0 4.9 0.0 0.0 16.6 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.7 23.9 0.4 0.6 0.0 22.9 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.7 9.8 12.3 15.5 8.9 5.8 8.7 19.5 16.2 18.3 18.2 19.1 21.5 91.2 0.0 6.2 98.6 50.3 4.2 0.5 5.5 2.8 0.9 2.0 3.3 2.1 1.5 6.8 7.3 0.0 5.5 0.7 7.2 3.9 2.6 3.8 20.7 6.2 58.4 5.4 5.0 12.8 1.1 1.6 11.8 7.1 19.2 0.0 7.9 35.0 4.3 0.6 0.0 5.8 8.2 8.2 5.9 3.8 1.6 0.3 2.0 5.4 131.2 4.7 11.3 0.0 14.1 168.5 9.4 12.4 0.4 5.2 1.1 3.9 3.6 9.6 0.7 0.0 2.0 3.0 0.7 1.5 6.2 3.7 2.9 5.1 1.1 5.5 3.6 PLOD3 LH3 ENSG00000106397 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" O60568 7 101205977-101218420 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "melanoma: 115.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 20.3;monocytes: 22.5;T-cells: 12.6" "Cell line enhanced" "Detected in all" "Karpas-707: 695.6;WM-115: 680.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001236 Uncertain "Secreted to extracellular matrix" NA NA 1600000 "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA001236: AB_1855474" "unprognostic (1.15e-1)" "prognostic unfavorable (1.91e-5)" "prognostic unfavorable (3.26e-4)" "unprognostic (1.39e-1)" "unprognostic (2.76e-3)" "unprognostic (1.04e-2)" "unprognostic (6.26e-3)" "unprognostic (1.11e-3)" "unprognostic (8.00e-3)" "unprognostic (1.18e-2)" "unprognostic (4.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.21e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (8.52e-3)" "unprognostic (9.87e-2)" 41.9 27.3 43.6 22.9 53.2 19.6 32.8 54.9 58.5 33.3 46.8 37.8 25.7 38.9 11.7 12.2 32.5 18.8 42.6 43.6 46.3 36.3 54.1 37.5 14.6 61.1 52.3 26.3 41.8 21.5 27.1 35.0 58.9 24.2 15.3 3.9 19.4 18.6 15.3 19.1 35.9 26.0 49.4 35.3 30.0 12.9 51.7 8.0 25.3 11.8 7.5 35.2 25.2 71.9 71.7 62.4 27.1 168.2 116.2 83.9 51.4 125.5 135.9 122.7 88.6 98.0 89.0 5.6 140.2 211.4 100.7 83.0 50.0 72.0 31.2 37.8 23.8 7.2 70.7 97.3 157.6 31.5 57.4 90.8 67.6 71.6 55.4 120.2 110.9 4.6 68.4 695.6 84.2 194.5 3.4 72.1 53.5 120.5 94.9 21.8 35.1 108.3 42.0 19.1 21.2 116.0 81.1 116.2 288.1 66.8 21.9 105.2 100.5 188.1 94.9 228.1 155.0 38.5 75.9 5.2 112.4 74.2 680.2 0.0 18.1 4.4 12.6 21.8 10.9 3.7 9.3 8.3 16.5 2.2 4.1 4.5 1.8 3.6 22.5 20.3 6.7 9.5 43.6 53.2 54.9 58.5 43.6 46.3 61.1 52.3 58.9 49.4 51.7 71.9 34.1 22.4 8.7 11.1 9.7 8.9 10.8 18.9 8.0 5.7 8.1 9.1 16.1 21.5 8.7 25.8 14.6 20.4 22.0 37.6 1.9 40.2 0.6 10.8 29.9 28.5 16.2 19.1 11.9 31.6 71.6 34.2 17.9 20.5 19.7 25.9 26.7 18.3 50.1 8.4 10.8 18.0 4.1 23.3 18.3 2.1 26.1 23.2 62.2 4.7 18.9 7.7 12.3 10.1 33.4 36.1 37.8 14.7 19.7 8.0 45.8 8.8 9.3 7.3 19.7 14.3 29.8 8.9 12.4 1.9 4.8 18.9 12.5 18.4 27.3 5.2 PM20D1 "Cps1, FLJ32569" ENSG00000162877 "Peptidase M20 domain containing 1" Q6GTS8 1 205828025-205850132 "Enzymes, Predicted secreted proteins" "Hydrolase, Lyase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pancreas: 78.0;skin 1: 33.8" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 20.9;Gastric mucus-secreting cells: 7.1;Proximal tubular cells: 7.1" "Cancer enriched" "Detected in some" 32 "urothelial cancer: 30.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 2.2" "Lineage enriched" "Detected in single" 6 "T-cells: 2.2" "Cell line enriched" "Detected in single" 9 "Karpas-707: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to digestive system" NA NA 3300000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.30e-1)" "unprognostic (4.07e-2)" "unprognostic (4.83e-1)" "unprognostic (4.08e-3)" "unprognostic (1.17e-3)" "unprognostic (3.11e-1)" "unprognostic (1.20e-1)" "unprognostic (5.50e-2)" "unprognostic (5.81e-2)" "unprognostic (4.57e-2)" "unprognostic (7.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (1.68e-2)" 0.8 0.0 0.2 0.1 0.2 0.0 1.2 0.0 0.3 0.1 1.2 0.1 0.1 0.1 0.5 0.0 0.4 0.0 0.3 0.2 0.3 6.3 0.2 0.2 1.1 0.3 0.3 0.3 78.0 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.0 0.0 33.8 0.1 0.0 0.2 1.0 2.9 0.0 0.3 0.1 0.1 0.0 0.4 2.2 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.3 0.0 0.5 0.1 0.4 1.3 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 2.2 0.3 0.2 0.2 0.0 0.3 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.3 0.8 0.0 0.0 1.6 1.1 0.0 0.0 0.0 0.6 0.5 0.0 0.0 1.5 0.0 0.0 0.0 2.1 0.0 0.9 0.1 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.4 3.2 20.9 0.3 0.5 7.1 0.0 0.0 0.0 0.7 0.3 0.1 0.0 3.5 0.2 0.0 1.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.0 1.5 1.5 0.6 0.0 0.0 1.8 0.2 0.0 7.1 0.0 0.8 0.0 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.9 2.4 0.0 0.1 PMVK "HUMPMKI, PMK, PMKA" ENSG00000163344 "Phosphomevalonate kinase" Q15126 1 154924740-154936719 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 266.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029900 Approved NA NA 15000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA029900: AB_10601390" "unprognostic (2.52e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.31e-1)" "unprognostic (1.81e-2)" "unprognostic (8.13e-2)" "unprognostic (5.47e-2)" "unprognostic (8.22e-2)" "prognostic favorable (9.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "prognostic favorable (4.96e-4)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" 39.9 56.4 99.0 29.8 100.1 15.3 35.0 97.9 108.9 33.4 95.0 39.9 45.9 25.9 17.7 77.7 37.2 17.2 63.1 93.9 96.4 53.8 91.9 30.1 34.6 98.6 97.4 35.8 41.6 58.2 60.3 23.7 96.0 32.4 22.2 19.8 34.0 27.1 79.1 69.2 44.2 27.7 96.4 45.7 40.5 26.6 102.3 27.9 31.5 47.4 36.8 31.9 37.9 99.8 51.8 72.9 46.7 72.5 43.6 30.9 48.5 40.5 29.3 38.9 37.0 30.6 101.0 75.1 75.9 49.3 40.5 49.4 65.3 63.9 17.8 103.3 28.9 34.1 104.1 29.0 40.0 51.4 29.3 36.3 58.7 70.2 49.6 19.5 40.0 65.9 36.8 221.7 41.3 108.3 40.8 51.0 41.0 121.7 95.0 60.3 29.8 171.1 66.1 38.4 37.7 91.1 44.1 75.7 51.9 35.0 146.7 91.1 32.7 35.8 29.2 84.4 62.1 174.0 153.2 131.8 58.9 83.9 46.7 28.0 80.9 91.8 68.2 205.6 110.1 114.8 93.1 70.6 93.6 111.1 59.1 59.1 6.9 59.7 219.4 96.5 134.3 80.0 99.0 100.1 97.9 108.9 93.9 96.4 98.6 97.4 96.0 96.4 102.3 99.8 22.7 57.7 37.5 9.4 42.2 69.8 105.9 95.8 51.8 38.5 67.1 68.3 57.3 78.6 42.2 53.3 8.4 235.7 31.5 65.0 266.1 69.6 9.0 45.0 28.5 29.8 66.4 35.6 5.1 71.3 108.1 45.1 46.9 44.2 22.2 49.8 39.3 146.9 141.0 37.0 7.0 78.9 67.1 67.9 49.5 13.5 42.6 47.8 65.8 3.7 49.5 119.1 41.2 8.0 11.8 61.7 61.7 47.8 58.8 53.7 219.3 246.1 22.1 27.4 32.9 46.0 48.4 51.3 51.3 81.0 90.5 227.7 45.1 162.6 79.9 76.2 POT1 "DKFZp586D211, hPot1" ENSG00000128513 "Protection of telomeres 1" Q9NUX5 7 124822386-124929983 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 41.5;Oligodendrocytes: 66.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068538 Supported Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA068538: AB_2686001" "unprognostic (1.39e-3)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (5.71e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.38e-3)" "unprognostic (7.88e-2)" "unprognostic (2.26e-2)" "unprognostic (1.51e-1)" "unprognostic (2.48e-2)" "unprognostic (9.89e-2)" "unprognostic (1.42e-1)" "unprognostic (2.92e-1)" "unprognostic (1.75e-2)" "unprognostic (4.77e-3)" "unprognostic (7.42e-2)" 5.6 5.7 3.2 5.7 3.8 4.1 10.4 3.7 3.6 7.9 4.0 5.6 4.5 9.5 6.1 4.5 8.1 6.0 6.2 3.2 4.2 9.7 9.9 6.1 8.8 3.9 3.4 10.1 5.3 9.8 6.4 6.9 4.1 7.1 6.4 9.9 3.9 6.7 3.2 4.1 4.2 7.2 3.8 8.1 5.8 13.8 3.2 13.0 12.9 4.4 9.6 7.7 4.5 6.1 24.0 6.9 14.0 9.9 9.2 16.2 10.3 12.1 14.9 14.3 19.7 7.3 25.9 24.4 8.5 11.1 23.6 9.5 14.8 15.0 21.7 21.4 17.5 18.9 10.3 3.2 15.4 22.6 12.4 13.1 13.6 12.8 21.8 14.5 16.6 10.1 38.1 51.9 15.0 4.1 29.8 12.5 17.4 13.2 14.1 19.1 14.0 27.5 9.9 9.8 13.9 16.6 18.7 19.8 15.6 20.3 8.0 12.3 8.4 14.3 5.5 19.1 17.1 23.2 27.0 39.8 20.4 23.6 22.7 0.6 2.2 1.0 2.3 2.3 4.3 3.2 2.6 3.0 2.5 2.5 4.3 3.0 0.4 3.7 1.8 2.2 2.8 1.9 3.2 3.8 3.7 3.6 3.2 4.2 3.9 3.4 4.1 3.8 3.2 6.1 9.7 6.4 4.1 36.9 10.1 4.6 6.7 5.5 13.1 9.2 7.1 7.1 8.8 8.6 3.6 12.9 10.4 7.0 8.0 1.5 19.6 5.0 19.3 4.3 6.9 7.1 9.0 16.0 34.7 4.5 8.0 6.9 8.2 4.2 3.8 9.4 7.1 10.5 6.3 8.4 41.5 4.0 2.0 10.9 7.0 8.3 8.7 8.7 16.0 24.4 5.6 12.6 4.1 37.2 66.8 3.8 1.7 4.5 7.6 2.8 0.8 11.2 4.9 10.0 0.0 5.4 6.3 35.2 14.4 7.6 2.6 4.5 8.5 4.8 4.9 3.5 POU6F1 "BRN5, MPOU, TCFB1" ENSG00000184271 "POU class 6 homeobox 1" 12 51186936-51217708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 20.9;Excitatory neurons: 22.2;Inhibitory neurons: 29.4;Oligodendrocyte precursor cells: 21.1;Oligodendrocytes: 23.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047021, HPA050411" Enhanced Supported "Nuclear bodies,Actin filaments" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies" "Actin filaments" "HPA047021: AB_2679905, HPA050411: AB_2681119" "unprognostic (4.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.48e-3)" "unprognostic (1.45e-2)" "unprognostic (2.72e-1)" "unprognostic (6.58e-2)" "unprognostic (9.70e-2)" "unprognostic (7.11e-3)" "unprognostic (4.45e-1)" "unprognostic (2.05e-1)" "prognostic favorable (6.61e-4)" "unprognostic (2.48e-2)" "unprognostic (9.36e-2)" "unprognostic (2.09e-3)" "unprognostic (1.74e-1)" "unprognostic (2.02e-1)" "unprognostic (2.33e-1)" 2.0 1.5 0.3 1.2 1.3 0.4 1.7 3.6 6.0 3.1 0.0 2.4 0.6 2.5 0.1 0.7 2.2 1.2 1.1 1.4 0.0 1.2 0.5 1.8 0.8 0.0 0.0 3.2 1.3 0.8 2.6 0.6 0.0 2.1 0.2 1.3 2.1 1.4 4.0 1.4 1.5 1.5 0.0 1.5 1.3 0.3 0.3 0.2 2.3 1.3 0.5 1.7 1.7 0.0 0.3 0.8 1.0 1.4 0.3 1.2 0.5 0.5 0.6 0.6 0.7 0.1 0.5 1.8 0.2 0.4 0.3 0.0 1.2 0.0 0.0 2.8 1.8 0.5 1.1 0.0 1.0 0.4 2.4 0.6 0.5 1.0 0.1 1.4 2.0 0.7 0.7 4.9 0.3 0.0 0.2 0.7 1.8 0.0 0.0 0.5 0.6 0.0 0.3 0.0 1.3 2.2 1.2 0.0 2.3 0.5 0.5 1.7 1.5 1.1 0.9 0.3 1.3 3.2 2.8 0.2 1.0 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 3.6 6.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4.5 6.4 2.8 20.9 2.1 3.1 1.3 0.4 0.0 10.0 2.3 1.3 3.1 1.5 1.7 7.3 4.2 0.6 1.1 0.1 1.9 0.8 5.3 0.9 1.7 4.8 0.0 2.7 22.2 2.0 0.2 3.2 0.5 1.6 5.1 2.4 3.6 1.2 0.3 1.7 29.4 0.3 4.1 2.2 3.9 3.7 5.9 1.1 1.8 8.4 1.7 3.7 0.0 21.1 23.6 1.6 0.2 6.8 0.7 1.8 0.0 0.7 2.7 7.9 0.0 3.8 4.1 0.1 0.7 0.5 2.8 0.4 1.8 0.2 0.6 0.7 PPCDC "FLJ14585, MDS018" ENSG00000138621 "Phosphopantothenoylcysteine decarboxylase" Q96CD2 15 75023586-75117462 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 71.4;granulocytes: 153.5;monocytes: 71.6" "Cell line enhanced" "Detected in all" "Karpas-707: 133.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045667 Approved Approved Cytosol NA NA 25000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA045667: AB_2679412" "unprognostic (8.66e-2)" "unprognostic (1.07e-3)" "unprognostic (6.03e-2)" "unprognostic (2.57e-2)" "unprognostic (2.95e-2)" "unprognostic (6.53e-2)" "unprognostic (1.76e-2)" "unprognostic (8.40e-2)" "unprognostic (1.72e-1)" "unprognostic (1.53e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (1.60e-2)" "unprognostic (7.67e-2)" "unprognostic (1.73e-1)" "unprognostic (3.43e-1)" "unprognostic (2.13e-3)" 11.1 19.1 7.4 10.8 8.8 19.7 10.9 8.3 8.4 9.7 8.7 11.5 9.7 8.3 9.8 19.0 10.8 8.4 8.5 6.9 8.0 17.2 13.1 10.8 16.4 9.2 8.8 9.0 16.5 21.3 9.3 9.2 8.5 13.0 9.4 7.6 13.9 7.6 11.9 9.0 9.9 5.4 8.0 18.8 11.3 9.7 8.6 12.1 11.2 5.9 12.3 11.2 10.0 10.3 15.6 28.8 11.8 9.2 7.0 6.4 10.1 15.5 7.0 20.3 15.9 16.9 41.2 17.7 26.8 7.8 12.5 15.9 19.2 25.6 10.4 62.6 23.4 31.1 18.8 18.3 19.9 18.3 38.7 8.6 16.7 21.0 32.3 8.2 16.6 25.8 21.3 133.2 14.8 30.0 10.9 28.1 18.9 32.9 13.4 18.2 23.0 38.3 15.3 22.2 28.3 8.3 22.9 31.3 34.6 13.4 38.7 23.4 9.4 20.6 14.4 10.5 27.6 40.5 29.3 30.1 12.7 45.9 23.7 47.2 23.1 153.5 11.6 65.6 19.4 15.7 10.6 13.0 17.6 8.6 11.7 14.5 139.7 18.5 71.6 71.4 12.7 15.8 7.4 8.8 8.3 8.4 6.9 8.0 9.2 8.8 8.5 8.0 8.6 10.3 10.2 16.0 5.2 2.9 10.5 3.8 6.1 8.5 8.6 2.8 9.6 8.8 4.2 4.3 9.7 9.2 0.0 17.5 16.0 19.7 25.4 17.3 1.0 8.2 4.3 10.7 4.2 11.6 1.4 15.3 13.6 7.4 14.8 8.3 12.0 9.9 10.4 5.3 20.0 8.4 1.7 10.9 12.2 15.7 6.7 2.5 4.4 15.5 14.2 2.8 20.0 4.7 8.2 2.5 4.6 18.0 38.1 5.3 33.9 6.5 10.5 19.0 12.2 10.7 6.6 6.3 8.7 6.9 15.7 10.8 4.0 10.9 9.7 11.3 11.7 13.6 PQBP1 "MRX2, MRX55, MRXS3, MRXS8, RENS1, SHS" ENSG00000102103 "Polyglutamine binding protein 1" O60828 X 48890197-48903143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001880 Supported Enhanced "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" "HPA001880: AB_1079671" "unprognostic (7.25e-2)" "prognostic favorable (1.48e-4)" "unprognostic (5.98e-2)" "unprognostic (2.09e-2)" "unprognostic (2.73e-2)" "unprognostic (1.52e-1)" "unprognostic (1.78e-2)" "unprognostic (1.09e-2)" "unprognostic (1.10e-1)" "unprognostic (7.48e-2)" "unprognostic (4.33e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.68e-7)" "unprognostic (2.68e-1)" "unprognostic (2.52e-3)" "unprognostic (3.97e-2)" "unprognostic (5.70e-3)" 38.8 50.6 35.5 25.6 36.9 46.0 39.3 38.1 44.2 47.9 31.1 50.0 39.2 42.5 22.7 48.6 41.0 24.2 43.0 36.7 40.2 41.7 61.0 35.6 31.1 38.8 37.3 58.4 62.8 28.1 50.5 18.2 38.6 42.2 20.4 21.5 43.2 28.3 65.0 52.0 42.2 25.3 38.4 45.2 52.1 13.8 39.0 38.6 38.6 32.3 29.0 39.2 43.2 40.0 100.6 124.3 64.5 63.2 58.2 40.8 48.8 57.3 67.1 116.8 70.7 146.3 45.0 91.8 46.2 40.0 88.1 79.9 110.6 42.6 43.5 80.8 95.2 78.1 94.6 109.5 55.9 95.5 69.8 50.7 81.4 96.8 95.5 46.5 67.0 35.9 75.7 169.0 50.1 167.5 41.5 94.3 60.3 69.3 139.6 66.7 63.0 209.4 75.5 66.2 95.7 49.4 75.3 82.6 66.5 48.0 103.5 68.9 58.6 51.1 92.2 65.6 77.4 99.9 106.5 69.5 29.0 88.0 53.8 41.8 81.9 53.1 56.4 79.1 74.7 83.9 78.2 56.2 96.9 70.4 81.5 74.9 23.4 76.1 73.0 86.9 114.3 84.5 35.5 36.9 38.1 44.2 36.7 40.2 38.8 37.3 38.6 38.4 39.0 40.0 37.0 41.7 65.9 6.2 65.4 111.8 86.1 99.5 85.4 36.7 76.9 97.2 39.0 54.3 68.6 31.3 12.5 58.5 53.4 85.1 49.0 59.9 6.2 37.5 38.6 54.5 70.1 38.7 4.4 95.8 56.1 53.9 39.8 54.3 70.5 36.6 43.5 45.0 70.2 18.5 3.9 68.2 77.3 72.2 113.5 4.9 69.9 56.2 88.9 3.7 96.6 47.4 55.6 3.5 4.8 73.7 123.6 43.6 105.9 54.2 151.1 108.5 51.6 27.7 39.5 64.4 69.8 2.7 17.7 69.5 117.3 54.6 62.9 67.0 67.9 69.3 PRDM1 "BLIMP1, PRDI-BF1" ENSG00000057657 "PR/SET domain 1" O75626 6 105993463-106109939 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 55.2" "Cell type enhanced" "Detected in many" "dendritic cells: 199.8;Langerhans cells: 199.2;Plasma cells: 786.9;T-cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 11.1;gdT-cell: 22.1;MAIT T-cell: 34.0;memory CD4 T-cell: 20.5;memory CD8 T-cell: 20.2;naive CD8 T-cell: 11.3;neutrophil: 12.5;T-reg: 29.4" "Group enriched" "Detected in many" 5 "granulocytes: 12.5;T-cells: 34.0" "Cell line enhanced" "Detected in many" "Karpas-707: 212.1;RPMI-8226: 42.4;U-266/70: 81.5;U-266/84: 57.0" "Region enriched" "Detected in single" 6 "olfactory bulb: 3.6" "Low region specificity" "Detected in many" "HPA030033, HPA075427" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoli Nucleoplasm "HPA030033: AB_10601050, HPA075427: " "unprognostic (9.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (4.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" "unprognostic (2.42e-1)" "unprognostic (1.81e-1)" "unprognostic (3.50e-2)" "unprognostic (7.56e-2)" "prognostic unfavorable (9.81e-5)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (2.45e-3)" "unprognostic (7.90e-2)" 6.6 2.1 1.6 20.0 1.6 20.3 6.8 5.5 1.8 15.7 3.1 15.2 9.2 17.2 1.3 55.2 5.5 12.7 1.7 1.5 2.8 2.5 4.5 10.1 15.9 3.2 1.8 4.9 1.9 2.5 1.4 5.1 2.7 3.4 17.2 1.3 9.3 2.4 4.3 9.1 12.6 5.5 2.4 13.6 15.2 1.2 2.9 4.2 9.0 2.2 27.8 19.6 20.2 3.4 1.4 0.5 1.1 0.0 1.6 2.1 0.2 7.2 23.3 2.3 3.7 1.4 9.2 2.0 0.4 13.8 0.3 0.5 0.0 3.6 2.5 21.7 0.1 0.4 4.9 0.0 3.6 0.8 1.6 2.3 11.6 3.3 9.7 0.7 2.9 1.0 1.4 212.1 0.4 0.0 0.1 0.5 0.8 1.4 0.0 0.5 0.0 42.4 2.1 0.3 0.0 0.3 1.0 0.9 0.0 1.6 1.0 2.4 1.5 3.1 1.8 2.1 7.2 81.5 57.0 4.9 5.1 1.3 2.1 2.4 0.8 11.1 22.1 1.2 34.0 2.5 20.5 20.2 0.5 1.0 1.8 11.3 12.5 4.7 0.3 0.4 29.4 2.6 1.6 1.6 5.5 1.8 1.5 2.8 3.2 1.8 2.7 2.4 2.9 3.4 93.1 0.0 5.1 0.3 42.1 19.5 8.6 15.0 3.4 0.6 2.8 3.4 1.5 0.0 19.1 3.7 52.1 0.7 199.8 129.8 0.0 0.3 0.9 15.9 101.0 41.1 1.8 6.1 1.8 0.2 0.7 18.5 19.4 62.6 3.8 9.9 6.4 2.5 19.8 0.0 19.2 15.0 10.2 38.0 199.2 0.3 0.0 64.5 37.4 23.4 30.4 0.5 89.6 0.5 0.1 7.8 103.7 1.2 786.9 4.0 3.2 0.3 13.0 1.1 0.0 5.3 30.1 0.5 2.3 43.9 41.5 0.7 184.3 1.6 8.7 91.9 PRDM5 PFM2 ENSG00000138738 "PR/SET domain 5" Q9NQX1 4 120684919-120922870 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 51.2;Early spermatids: 75.6;Inhibitory neurons: 31.9;Late spermatids: 31.0;Oligodendrocyte precursor cells: 52.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "eosinophil: 7.5;neutrophil: 5.4" "Lineage enriched" "Detected in single" 32 "granulocytes: 7.5" "Cell line enhanced" "Detected in many" "U-266/84: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051406 Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear bodies" Nucleoli "HPA051406: AB_2681472" "unprognostic (7.74e-2)" "unprognostic (8.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.09e-1)" "unprognostic (7.20e-2)" "unprognostic (9.30e-2)" "unprognostic (3.28e-2)" "unprognostic (4.52e-2)" "unprognostic (5.09e-2)" "unprognostic (8.71e-2)" "unprognostic (6.29e-2)" "unprognostic (4.13e-1)" "unprognostic (3.00e-2)" "unprognostic (4.91e-4)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (5.56e-3)" 3.0 4.0 1.8 1.6 2.0 3.5 3.0 3.2 2.0 5.2 4.2 3.2 1.3 6.0 2.8 2.2 4.6 2.4 3.0 1.6 3.2 1.9 0.4 4.2 0.9 4.1 4.0 10.3 4.8 8.6 3.9 3.5 4.0 4.1 2.9 4.7 1.8 4.3 1.6 1.5 1.8 4.4 4.7 2.4 2.1 3.6 2.9 1.4 5.8 3.0 0.8 2.9 3.3 4.4 2.2 3.4 7.8 0.1 4.5 9.3 9.2 4.7 9.9 4.7 4.2 4.4 1.2 0.4 1.2 6.2 4.5 0.1 0.0 1.0 6.0 0.0 1.4 2.9 3.1 0.3 4.9 10.0 0.1 6.6 2.9 3.3 4.1 4.3 3.4 1.2 0.0 14.2 5.7 0.4 1.5 0.1 5.7 0.8 2.7 0.0 9.3 6.1 1.6 0.0 1.4 6.2 0.0 0.1 0.9 4.0 6.4 4.1 1.4 0.2 2.7 4.8 4.6 13.0 19.7 0.1 3.6 0.1 3.6 0.1 0.0 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.4 0.0 0.0 0.0 0.0 0.0 1.8 2.0 3.2 2.0 1.6 3.2 4.1 4.0 4.0 4.7 2.9 4.4 7.1 12.8 5.6 51.2 0.5 1.7 2.7 2.4 9.1 9.1 1.1 2.4 8.2 2.8 3.8 1.8 8.4 1.0 0.2 1.5 1.9 2.3 75.6 1.4 9.4 6.3 3.6 0.0 25.0 2.5 2.6 9.6 2.6 1.4 2.5 15.5 3.6 0.0 0.8 0.0 31.9 3.6 4.1 0.3 0.7 31.0 8.7 0.6 1.8 23.4 0.2 7.6 0.0 52.8 8.0 1.5 0.8 9.4 0.7 2.6 0.1 0.2 1.8 7.5 6.6 10.1 6.6 8.2 3.5 4.6 1.7 0.5 1.2 14.9 3.0 0.7 PROSER3 "C19orf55, FLJ30657" ENSG00000167595 "Proline and serine rich 3" Q2NL68 19 35758143-35771028 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 89.6;Rod photoreceptor cells: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 10.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058492 Approved Approved "Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA058492: AB_2683733" "unprognostic (1.35e-2)" "unprognostic (1.29e-2)" "unprognostic (6.74e-3)" "unprognostic (3.81e-2)" "unprognostic (1.75e-1)" "unprognostic (9.29e-3)" "unprognostic (1.25e-3)" "unprognostic (5.13e-2)" "unprognostic (2.52e-1)" "unprognostic (1.28e-1)" "unprognostic (2.52e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (3.74e-7)" "unprognostic (8.60e-2)" "unprognostic (2.41e-1)" "unprognostic (2.87e-2)" "unprognostic (9.54e-2)" 2.3 2.4 3.4 4.3 3.7 5.2 2.3 2.3 5.2 3.4 6.7 2.9 1.8 3.8 2.8 2.5 4.3 3.3 2.5 2.8 0.6 1.9 1.3 2.7 3.0 3.6 2.7 4.1 5.1 3.1 3.8 2.8 1.6 2.4 1.9 3.6 2.6 3.1 1.7 5.8 2.6 3.3 0.0 2.9 4.0 8.8 2.6 4.6 3.8 1.4 2.6 3.1 2.9 2.5 9.3 26.7 9.4 9.3 3.7 3.8 3.1 6.7 7.6 7.3 7.7 8.2 6.3 5.2 7.3 6.4 3.5 5.5 4.0 11.8 4.9 12.5 6.8 7.5 12.2 3.4 3.2 6.0 15.6 4.6 6.5 10.2 9.0 5.7 3.2 6.7 6.6 9.3 6.4 4.6 10.7 2.5 2.6 5.4 3.9 8.2 2.3 3.9 4.7 9.8 9.2 8.1 7.4 5.4 1.0 3.5 8.7 5.1 8.2 7.7 8.1 8.0 7.2 11.9 8.6 4.2 8.0 3.8 6.1 5.7 1.7 4.0 1.1 1.0 1.9 2.4 1.7 1.0 0.4 2.6 1.4 0.5 10.3 0.8 1.0 1.5 1.6 0.2 3.4 3.7 2.3 5.2 2.8 0.6 3.6 2.7 1.6 0.0 2.6 2.5 2.6 9.6 1.5 1.6 7.4 0.0 12.8 0.0 6.2 10.8 3.1 2.9 1.4 8.6 1.8 11.0 89.6 8.2 9.4 5.3 0.0 5.9 30.0 8.9 6.3 3.4 9.5 9.5 3.7 1.9 5.4 5.6 10.2 3.6 2.5 4.4 7.5 2.6 2.8 6.7 2.1 3.9 0.0 2.8 0.0 21.2 14.3 3.3 0.0 1.0 7.0 6.0 13.4 1.0 2.1 5.3 3.4 4.1 3.4 9.2 5.3 1.8 14.6 39.5 6.6 7.9 5.0 27.2 6.5 4.0 0.0 7.3 6.6 15.4 4.7 5.7 PRR33 "C11orf89, LOC728008" ENSG00000283787 "Proline rich 33" 11 1888078-1891895 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.4;lymphoid tissue: 28.3;skeletal muscle: 35.2" "Cell type enriched" "Detected in single" 14 "Cardiomyocytes: 2.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.4" "Group enriched" "Detected in some" 5 "Daudi: 3.0;HDLM-2: 8.6;Karpas-707: 6.1;U-937: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" 4.8 23.4 0.0 6.1 0.0 9.7 3.0 0.0 0.2 6.1 0.1 3.0 1.3 2.8 0.0 3.1 3.1 1.5 7.2 0.0 0.1 0.5 1.1 2.7 6.3 0.2 0.1 0.5 0.6 0.0 0.6 1.4 0.2 1.3 0.0 0.0 3.3 0.0 35.2 11.0 6.1 0.0 0.2 28.3 2.9 1.2 0.2 0.0 1.7 4.0 0.0 6.9 4.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 1.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 QPCTL FLJ20084 ENSG00000011478 "Glutaminyl-peptide cyclotransferase like" Q9NXS2 19 45692403-45703989 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 5.5;granulocytes: 5.7;Inhibitory neurons: 6.5;Plasma cells: 9.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040797 Approved Supported "Golgi apparatus" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA040797: AB_10794148" "unprognostic (6.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.09e-1)" "unprognostic (7.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.26e-1)" "unprognostic (8.41e-3)" "unprognostic (2.30e-2)" "unprognostic (9.46e-2)" "unprognostic (1.69e-1)" "unprognostic (3.14e-2)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.15e-8)" "unprognostic (1.07e-1)" "unprognostic (1.75e-1)" "unprognostic (4.02e-2)" "unprognostic (5.71e-2)" 4.1 7.8 3.9 3.1 3.9 4.1 4.9 3.6 4.8 4.9 4.1 5.9 4.7 4.8 3.7 4.7 4.8 2.5 3.4 4.2 4.0 5.3 9.2 6.2 4.7 4.5 3.8 6.6 7.5 4.4 7.0 3.7 4.5 6.5 3.9 2.1 6.7 3.4 1.5 5.2 5.5 2.5 3.2 8.5 6.1 4.4 4.2 2.4 6.7 0.8 3.5 4.6 4.4 3.9 16.7 10.8 8.5 36.9 8.6 4.1 6.4 10.3 15.7 15.0 24.7 11.2 12.3 19.7 11.1 11.5 15.4 9.5 10.0 11.9 8.9 5.0 12.7 6.7 10.9 24.6 14.6 7.5 12.0 7.6 14.9 12.6 17.3 10.7 13.6 10.8 9.7 32.1 9.5 13.0 7.0 7.7 5.5 14.2 5.4 7.8 6.4 16.5 16.2 8.0 7.6 4.7 10.6 8.8 18.2 3.7 6.4 10.6 8.4 7.4 12.4 7.3 10.4 28.6 20.2 18.2 26.0 17.2 5.8 1.4 0.3 0.2 1.4 0.5 0.9 0.9 0.6 0.3 0.8 0.6 0.5 0.7 1.3 1.4 0.3 1.0 0.3 0.2 3.9 3.9 3.6 4.8 4.2 4.0 4.5 3.8 4.5 3.2 4.2 3.9 0.5 0.0 1.5 2.3 3.3 1.3 1.2 1.1 0.6 1.1 0.7 0.6 0.8 1.5 1.2 0.0 0.0 0.8 2.1 1.2 0.0 0.6 5.4 0.9 1.4 0.7 0.0 1.3 5.5 0.4 1.4 0.7 1.5 1.4 5.7 0.7 0.0 1.3 0.9 1.7 6.5 0.4 0.0 0.6 1.8 1.3 0.0 1.6 1.8 0.0 0.7 0.3 1.0 3.5 1.6 0.6 0.1 0.0 9.8 1.2 0.7 0.1 2.2 2.4 0.0 0.6 1.1 1.0 0.3 1.4 1.1 0.8 2.4 1.5 1.0 0.5 RAB28 ENSG00000157869 "RAB28, member RAS oncogene family" P51157 4 13361354-13484365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 119.9;Inhibitory neurons: 140.4;Spermatocytes: 123.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044575 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044575: AB_10959460" "unprognostic (2.10e-1)" "unprognostic (1.95e-1)" "unprognostic (1.59e-2)" "unprognostic (1.81e-1)" "unprognostic (2.17e-1)" "unprognostic (2.46e-2)" "unprognostic (3.90e-2)" "unprognostic (1.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.69e-2)" "unprognostic (2.09e-2)" "unprognostic (1.07e-1)" "unprognostic (4.47e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (5.31e-3)" "prognostic favorable (1.61e-4)" 17.1 18.9 22.9 12.8 25.2 19.3 20.3 39.5 29.2 15.3 24.9 16.2 11.0 22.5 18.8 12.0 21.9 15.5 30.4 23.7 29.5 16.4 11.9 16.1 18.3 22.3 26.7 22.4 10.0 23.9 19.3 19.5 24.7 16.2 18.1 55.4 12.1 16.0 7.2 19.9 11.3 17.3 24.3 17.2 14.5 37.7 29.6 18.4 19.5 13.3 16.7 13.2 13.3 28.9 22.0 11.4 36.3 18.6 18.7 34.8 19.0 19.7 22.7 21.7 28.9 11.3 22.7 26.0 12.5 19.3 46.0 11.1 31.4 17.6 39.3 16.7 15.7 18.6 20.1 10.8 18.3 21.2 10.9 16.0 23.3 19.8 18.7 26.5 23.9 32.9 37.0 97.1 30.4 8.8 45.3 52.7 50.7 16.4 19.9 28.6 22.8 21.5 18.7 11.9 28.7 17.3 17.0 12.2 28.1 28.2 13.7 23.8 16.5 28.8 12.6 23.8 30.7 24.0 18.0 34.6 25.7 38.3 38.6 21.0 16.2 26.1 16.5 15.6 17.0 18.4 15.3 16.2 16.8 17.9 20.3 16.5 15.1 20.6 14.4 12.9 17.2 10.6 22.9 25.2 39.5 29.2 23.7 29.5 22.3 26.7 24.7 24.3 29.6 28.9 17.8 6.4 6.4 81.0 22.3 27.4 26.7 38.7 22.2 31.0 15.6 14.0 18.2 2.8 16.7 7.3 33.3 23.3 15.1 7.9 19.6 12.9 19.1 19.6 17.7 18.4 10.3 9.9 119.9 14.2 22.7 27.5 11.7 8.2 5.1 12.4 12.8 6.8 17.0 32.0 140.4 11.0 32.6 15.1 18.2 20.6 18.6 14.2 30.2 49.6 16.7 44.5 19.6 97.0 79.8 11.2 7.8 24.0 19.2 21.4 6.3 18.8 36.5 44.1 19.7 24.1 20.1 123.9 63.7 20.6 30.0 27.9 21.3 10.6 11.6 19.0 RAB33A RabS10 ENSG00000134594 "RAB33A, member RAS oncogene family" Q14088 X 130171962-130184870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.5;choroid plexus: 16.4;heart muscle: 15.2" "Cell type enhanced" "Detected in many" "granulocytes: 22.9;Melanocytes: 12.4;NK-cells: 22.6;Oligodendrocytes: 23.5;T-cells: 12.9" "Group enriched" "Detected in many" 6 "glioma: 10.7;melanoma: 2.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 111.4;Karpas-707: 126.8;U-266/70: 88.5;U-937: 55.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059737 Uncertain Uncertain Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA059737: AB_2684115" "unprognostic (5.40e-2)" "unprognostic (6.64e-3)" "unprognostic (3.48e-2)" "unprognostic (8.47e-3)" "unprognostic (4.88e-2)" "unprognostic (1.17e-2)" "unprognostic (2.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.12e-2)" "unprognostic (4.16e-2)" "unprognostic (3.03e-2)" "unprognostic (8.28e-2)" "unprognostic (7.00e-6)" "unprognostic (2.51e-1)" "unprognostic (6.35e-2)" "unprognostic (3.45e-2)" "unprognostic (1.61e-1)" 2.3 1.3 23.6 4.0 28.2 6.3 1.3 27.9 31.6 2.3 16.4 0.9 0.7 1.7 0.5 0.5 1.6 2.6 15.2 24.4 24.4 1.7 0.9 1.7 11.6 29.0 24.7 1.4 0.2 2.0 2.2 1.4 29.7 0.4 1.0 7.6 0.5 0.1 0.1 1.1 2.2 0.7 27.8 2.5 1.4 0.6 25.7 4.8 0.6 0.2 12.3 1.7 0.8 41.5 0.3 0.2 7.5 0.0 3.2 1.0 0.1 1.0 2.2 1.9 3.2 0.1 0.8 5.8 0.1 0.6 0.5 0.2 9.4 0.2 2.0 30.2 0.1 35.0 0.1 0.0 31.3 28.4 111.4 1.0 0.2 0.6 1.3 1.0 0.8 34.7 0.1 126.8 0.3 0.3 13.1 9.7 1.1 0.1 1.3 0.0 0.0 1.6 0.2 0.0 24.3 19.4 0.2 0.3 0.5 0.4 0.0 15.2 0.2 0.1 0.1 0.4 0.2 88.5 29.7 0.0 3.9 55.1 0.0 39.9 1.3 87.4 32.0 0.8 20.0 20.2 29.0 32.5 10.0 8.8 27.8 40.0 4.1 19.5 5.4 1.0 72.8 18.1 23.6 28.2 27.9 31.6 24.4 24.4 29.0 24.7 29.7 27.8 25.7 41.5 1.7 0.0 1.1 1.6 3.2 1.9 0.6 0.5 1.2 10.9 0.3 1.0 8.4 2.8 0.2 0.0 2.1 0.9 8.9 0.0 0.0 0.0 1.2 0.4 0.8 2.0 0.0 6.6 4.0 0.2 1.3 4.5 0.0 0.8 22.9 2.9 2.5 0.1 1.9 5.0 3.2 0.4 2.0 0.3 12.0 1.2 1.8 6.3 12.4 1.9 2.5 1.6 22.6 4.5 23.5 0.8 0.0 0.4 3.3 0.4 0.0 0.2 0.3 9.3 0.0 0.0 2.2 0.1 1.2 0.2 1.1 1.4 12.9 0.2 0.3 0.6 RAB33B DKFZP434G099 ENSG00000172007 "RAB33B, member RAS oncogene family" Q9H082 4 139453232-139476609 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 72.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 22.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048367 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA048367: AB_2680372" "unprognostic (2.11e-1)" "unprognostic (1.19e-1)" "unprognostic (4.87e-2)" "unprognostic (1.12e-1)" "unprognostic (3.11e-1)" "unprognostic (2.09e-1)" "unprognostic (3.18e-1)" "unprognostic (4.50e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-2)" "unprognostic (9.45e-2)" "unprognostic (2.36e-2)" "unprognostic (4.37e-3)" "unprognostic (1.48e-1)" "unprognostic (2.59e-1)" "unprognostic (8.06e-3)" "prognostic favorable (9.19e-4)" 8.4 5.2 3.7 5.2 4.4 12.8 7.1 7.0 5.3 8.1 2.2 4.1 3.8 9.5 4.2 6.6 5.6 6.0 6.5 3.3 4.4 5.0 16.7 6.8 6.5 5.5 4.5 9.9 10.0 4.1 2.8 9.0 5.8 6.8 4.1 4.1 4.2 5.6 4.2 4.9 4.2 8.4 4.6 7.5 5.4 3.6 4.8 5.4 6.3 5.2 5.8 5.6 3.1 7.4 5.1 1.9 5.6 7.7 12.6 12.3 9.4 6.1 8.5 5.2 6.4 5.5 8.0 10.7 3.0 7.0 2.6 4.8 6.1 5.4 6.2 10.1 4.0 3.7 4.5 6.4 12.6 6.8 8.4 9.5 5.9 6.6 6.2 9.4 15.3 6.7 4.1 20.6 3.9 3.5 5.8 6.0 3.9 8.5 3.2 7.3 8.4 4.7 7.3 3.4 7.4 7.6 4.3 8.5 10.1 6.2 3.9 4.7 10.7 6.2 4.5 10.6 3.4 10.9 13.3 6.9 6.2 7.3 5.6 4.3 3.4 8.7 3.6 3.5 5.8 4.3 4.5 4.0 2.3 3.6 5.6 5.1 22.6 4.3 3.4 2.8 5.2 3.5 3.7 4.4 7.0 5.3 3.3 4.4 5.5 4.5 5.8 4.6 4.8 7.4 13.9 6.4 7.7 5.2 15.1 9.9 7.2 3.4 18.2 5.0 10.0 6.3 10.1 5.7 4.1 3.7 0.0 6.3 9.1 5.3 1.9 5.3 34.1 13.7 11.3 12.0 8.4 3.8 5.9 4.7 5.7 10.7 7.1 10.6 6.3 3.3 11.4 19.7 6.6 3.3 7.5 8.2 2.0 9.4 8.9 72.1 10.5 7.1 1.8 10.3 8.6 5.9 3.1 10.1 8.9 6.2 5.2 12.8 10.9 6.8 6.3 4.5 6.4 8.5 6.6 12.8 9.9 4.6 4.3 12.9 11.6 16.8 13.2 3.4 6.5 5.9 RAB39B "MRX72, WSN" ENSG00000155961 "RAB39B, member RAS oncogene family" Q96DA2 X 155258235-155264491 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Autism spectrum disorder, Disease variant, Mental retardation, Parkinson disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.7;retina: 9.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.8;Horizontal cells: 10.1;Inhibitory neurons: 9.8;Muller glia cells: 11.6;Oligodendrocytes: 10.3" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 27.8;Karpas-707: 35.6;U-266/70: 35.5;U-266/84: 26.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001114, HPA042505" Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA001114: AB_1079732, HPA042505: AB_2678030" "prognostic favorable (8.95e-4)" "unprognostic (1.20e-3)" "unprognostic (3.52e-2)" "unprognostic (7.10e-5)" "unprognostic (1.77e-1)" "unprognostic (7.47e-4)" "unprognostic (2.19e-1)" "unprognostic (6.00e-4)" "unprognostic (1.78e-1)" "unprognostic (5.64e-2)" "unprognostic (3.87e-4)" "unprognostic (5.41e-2)" "unprognostic (1.72e-1)" "unprognostic (7.21e-2)" "unprognostic (4.94e-2)" "unprognostic (6.35e-2)" "unprognostic (3.24e-1)" 0.2 1.9 6.5 2.8 6.7 0.9 0.7 6.8 10.7 0.4 3.0 0.7 0.6 0.3 6.4 0.3 0.5 0.6 0.3 7.0 7.0 0.7 0.3 0.6 5.3 6.4 6.1 0.4 2.5 3.8 6.5 0.2 6.9 1.9 0.6 9.9 0.4 1.3 0.0 0.0 1.2 0.2 6.1 3.1 1.3 0.9 7.0 5.3 2.4 0.0 5.9 0.8 0.1 8.2 0.0 0.4 5.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 27.8 1.2 0.1 14.9 0.0 0.0 0.2 0.1 11.8 0.5 2.3 0.0 0.0 1.7 0.0 4.8 0.1 0.0 0.4 7.8 0.9 0.0 10.3 0.0 35.6 0.1 2.1 10.3 0.0 6.9 0.0 0.6 0.0 0.0 2.3 0.0 0.0 13.4 10.3 0.0 0.0 6.4 1.8 0.4 0.2 0.0 0.7 2.2 0.0 1.1 35.5 26.7 6.2 6.2 0.0 0.0 0.8 0.3 2.2 4.6 0.2 4.7 4.2 6.0 6.0 4.6 2.8 6.1 6.9 2.7 3.3 0.4 1.1 4.8 3.2 6.5 6.7 6.8 10.7 7.0 7.0 6.4 6.1 6.9 6.1 7.0 8.2 0.9 0.0 0.0 2.6 7.9 0.5 0.5 0.0 0.0 11.8 0.6 0.9 2.4 0.0 0.0 1.8 8.4 0.0 7.6 0.0 0.0 0.2 0.2 0.0 0.7 0.8 1.8 3.0 7.7 0.9 0.0 0.7 1.1 0.1 0.0 2.6 1.8 0.0 0.1 10.1 9.8 0.0 0.0 0.3 3.1 0.0 0.0 1.5 3.6 1.0 2.2 11.6 6.2 8.0 10.3 0.4 0.0 1.9 9.2 0.6 0.0 0.9 0.0 8.0 0.0 0.1 2.4 0.4 0.8 0.0 0.1 0.0 9.1 8.2 0.0 0.0 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RAPGEF1 "C3G, GRF2" ENSG00000107263 "Rap guanine nucleotide exchange factor 1" Q13905 9 131576770-131740074 "Plasma proteins, Predicted intracellular proteins" Neurogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 228.6" "Cell type enhanced" "Detected in all" "Horizontal cells: 131.2;Langerhans cells: 108.6;Microglial cells: 123.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006426, HPA075984" Enhanced Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA006426: AB_1856070, HPA075984: AB_2686771" "unprognostic (1.00e-1)" "unprognostic (8.19e-2)" "unprognostic (2.12e-2)" "unprognostic (2.43e-2)" "unprognostic (2.34e-1)" "unprognostic (2.38e-1)" "unprognostic (4.11e-2)" "unprognostic (1.74e-1)" "unprognostic (5.50e-2)" "unprognostic (6.04e-2)" "unprognostic (1.94e-2)" "unprognostic (1.62e-1)" "prognostic favorable (1.18e-5)" "unprognostic (5.66e-2)" "unprognostic (1.99e-2)" "unprognostic (1.49e-1)" "unprognostic (3.73e-2)" 37.3 24.0 41.4 53.9 72.6 53.2 26.8 27.0 37.1 20.4 37.9 31.9 23.9 25.6 8.0 23.6 25.5 23.7 57.8 40.8 40.2 23.0 23.0 43.3 56.1 35.8 36.9 16.3 47.8 20.1 16.4 56.4 32.3 21.5 23.4 27.5 20.2 21.4 228.6 21.9 35.3 30.4 25.6 41.9 29.1 15.9 43.8 35.1 22.7 104.8 63.1 25.8 18.2 20.2 34.5 39.4 39.1 39.6 39.1 42.0 149.2 29.0 59.0 33.0 23.6 49.0 22.1 61.9 35.6 58.8 70.7 61.4 45.1 40.5 16.4 144.6 18.6 18.3 67.2 26.2 32.8 76.1 80.4 32.2 73.0 43.3 51.0 33.1 60.4 70.8 49.7 119.1 43.4 35.7 54.0 27.0 39.6 34.1 35.2 53.0 91.0 86.8 14.9 41.1 33.0 32.9 42.5 39.8 42.3 39.0 38.1 63.1 64.4 88.1 36.7 56.4 44.7 39.8 37.3 122.0 41.9 32.0 21.6 3.1 1.2 1.6 3.4 2.2 2.0 4.9 2.3 2.3 1.4 2.9 0.5 1.5 1.3 1.3 2.4 1.6 1.8 1.6 41.4 72.6 27.0 37.1 40.8 40.2 35.8 36.9 32.3 25.6 43.8 20.2 73.5 6.4 13.8 27.1 35.6 18.7 9.3 10.9 5.2 19.5 10.8 13.5 16.2 14.3 12.3 5.5 14.6 22.7 49.7 23.3 5.9 8.2 2.6 13.0 9.4 43.0 12.1 1.7 47.5 18.6 35.3 11.8 17.9 17.8 20.3 14.0 22.5 17.4 26.4 131.2 66.6 14.9 8.2 23.9 108.6 2.5 8.7 51.6 32.0 123.7 59.8 19.7 27.8 61.3 24.7 17.1 19.1 12.0 88.0 11.7 16.8 9.2 16.7 13.4 6.6 13.4 10.3 5.1 11.8 5.6 11.4 51.7 31.0 5.8 14.0 10.8 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 441.1;Inhibitory neurons: 416.6;Microglial cells: 142.4;Oligodendrocyte precursor cells: 303.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 21.5;SCLC-21H: 8.3;U-266/70: 11.0;U-266/84: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 5.3 45.6 105.0 1.8 113.1 0.2 6.8 69.8 141.6 6.1 49.1 2.1 2.4 5.6 3.1 2.6 3.4 4.7 7.5 142.3 77.7 5.3 34.6 11.4 2.0 61.2 75.0 13.1 4.5 4.0 6.2 2.6 60.8 4.1 1.6 18.8 2.4 3.3 1.5 14.9 2.3 5.4 55.7 0.6 7.7 4.7 128.3 2.2 5.5 1.7 2.0 5.3 3.2 121.9 0.1 0.2 3.2 0.5 0.1 0.3 0.1 1.1 0.7 0.1 0.3 0.0 3.7 0.0 0.2 0.0 0.2 0.7 2.8 0.7 0.3 0.2 5.9 0.6 2.8 0.0 0.0 3.2 0.9 0.1 0.9 0.0 0.0 3.2 3.5 1.6 0.0 21.5 0.1 0.1 0.2 0.2 0.4 1.8 0.4 0.1 0.7 0.0 0.0 6.6 8.3 3.0 0.1 0.1 1.1 1.6 0.1 0.1 1.0 0.1 0.3 0.0 0.3 11.0 23.0 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.0 113.1 69.8 141.6 142.3 77.7 61.2 75.0 60.8 55.7 128.3 121.9 14.7 3.2 2.8 23.2 1.9 6.1 1.1 0.1 2.8 3.5 5.5 3.9 6.9 0.0 0.0 0.0 45.9 0.1 0.1 0.0 0.0 1.7 2.5 1.2 0.2 32.4 7.8 0.0 441.1 2.7 0.1 4.8 3.1 0.9 0.0 3.3 23.9 11.8 0.1 1.7 416.6 0.5 0.0 1.2 2.1 1.4 4.4 0.2 3.6 142.4 0.0 1.3 0.0 303.1 28.4 1.5 0.1 1.5 1.6 0.5 0.0 0.0 0.0 9.2 0.0 0.4 1.2 0.7 4.1 1.6 3.8 0.1 0.6 4.2 0.1 0.7 RASAL3 FLJ21438 ENSG00000105122 "RAS protein activator like 3" Q86YV0 19 15451624-15464544 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 23.5;intestine: 19.8;lung: 10.6;lymphoid tissue: 39.4" "Cell type enhanced" "Detected in many" "B-cells: 39.4;dendritic cells: 70.9;granulocytes: 39.3;NK-cells: 139.0;T-cells: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 30.6;HEL: 25.5;HMC-1: 46.7;Karpas-707: 52.5;NB-4: 27.8;RPMI-8226: 23.5;TIME: 35.5;U-937: 34.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043417 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA043417: AB_2678473" "unprognostic (2.72e-2)" "prognostic favorable (8.75e-4)" "unprognostic (3.27e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.31e-1)" "prognostic favorable (3.07e-4)" "unprognostic (1.82e-2)" "unprognostic (6.21e-3)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (3.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.98e-1)" "unprognostic (1.90e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" 3.7 2.6 2.8 17.3 2.9 23.5 1.9 3.1 3.6 1.8 2.9 4.2 4.5 1.5 0.7 2.8 2.2 3.6 1.4 2.9 3.2 3.7 3.6 10.6 32.8 4.2 3.3 0.9 1.4 1.2 1.5 1.0 3.9 2.8 2.3 0.1 3.5 0.9 0.7 1.5 19.8 1.2 4.1 39.4 5.4 0.5 4.2 23.8 3.8 0.4 19.4 4.2 2.3 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 6.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 30.6 0.0 25.5 0.0 0.0 0.4 20.4 46.7 0.1 0.0 0.0 0.0 0.0 0.2 8.0 0.0 52.5 0.0 0.4 10.9 27.8 0.0 0.0 0.0 3.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 8.7 35.5 0.0 0.0 0.0 0.0 0.4 10.1 15.1 0.0 34.1 0.1 6.4 2.3 12.9 18.4 4.7 10.7 3.1 11.7 20.4 3.4 3.5 9.7 11.8 3.4 12.4 12.8 4.2 9.2 5.5 2.8 2.9 3.1 3.6 2.9 3.2 4.2 3.3 3.9 4.1 4.2 5.2 4.1 3.2 5.6 0.0 39.4 0.3 0.0 0.3 0.0 0.0 2.0 2.2 2.5 2.8 1.4 0.0 0.0 0.2 70.9 0.0 0.0 0.2 0.7 5.4 0.4 5.4 0.0 7.4 0.1 0.6 0.2 1.0 2.6 0.4 39.3 0.0 3.9 4.6 11.3 0.0 0.1 0.0 0.0 11.6 3.5 1.7 0.0 17.2 0.0 13.1 14.2 0.1 139.0 0.5 0.1 0.2 0.0 1.2 23.7 0.2 0.0 1.5 5.7 0.1 0.0 0.5 1.5 0.4 0.6 0.3 0.6 0.4 76.7 1.0 0.2 0.1 RASGRF1 "CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187" ENSG00000058335 "Ras protein specific guanine nucleotide releasing factor 1" Q13972 15 78959906-79090780 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 26.5;lung: 7.5;retina: 7.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 80.6;Excitatory neurons: 80.9;Inhibitory neurons: 91.2;Oligodendrocytes: 121.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 8.5;BEWO: 7.7;Karpas-707: 10.4;RPMI-8226: 13.0;U-2 OS: 15.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010413, HPA041965" Approved Supported "Golgi apparatus" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "CAB010413: AB_2238127, HPA041965: AB_10793939" "unprognostic (2.57e-3)" "unprognostic (3.08e-2)" "unprognostic (3.14e-2)" "prognostic favorable (6.14e-6)" "unprognostic (1.90e-1)" "unprognostic (1.15e-3)" "unprognostic (5.37e-2)" "unprognostic (6.16e-2)" "unprognostic (7.58e-2)" "unprognostic (3.25e-2)" "unprognostic (1.00e-1)" "unprognostic (2.03e-1)" "unprognostic (4.02e-6)" "unprognostic (2.35e-1)" "unprognostic (8.02e-2)" "unprognostic (3.81e-2)" "unprognostic (8.81e-2)" 0.1 0.1 4.2 1.0 4.1 0.0 0.1 24.4 24.4 0.6 0.0 0.2 0.2 0.4 0.1 0.1 0.4 0.1 0.0 12.2 6.4 0.7 0.0 7.5 1.3 13.9 10.2 0.8 2.3 0.6 1.1 0.2 16.4 0.5 0.2 7.4 0.1 0.2 0.0 0.0 1.4 0.1 8.7 0.6 0.2 0.3 14.9 0.5 0.0 0.0 1.4 0.3 0.1 26.5 8.5 0.1 0.1 0.0 0.0 0.0 7.7 0.0 0.4 0.5 1.2 0.0 1.5 0.4 0.2 0.0 0.6 0.7 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.4 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 10.4 1.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.9 13.0 0.1 0.3 0.8 0.0 0.0 0.1 1.6 0.7 0.0 1.7 0.0 0.0 15.1 0.0 0.3 0.0 3.8 2.9 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 4.1 24.4 24.4 12.2 6.4 13.9 10.2 16.4 8.7 14.9 26.5 0.2 3.2 80.6 8.5 4.5 0.6 0.6 0.2 0.0 13.7 0.2 0.1 1.0 0.0 1.9 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.2 0.6 0.4 0.5 0.0 0.0 80.9 0.0 2.7 0.3 0.0 1.8 0.0 0.0 0.0 0.0 2.0 25.2 91.2 0.0 0.0 0.3 16.1 0.0 0.0 1.8 3.6 5.6 0.6 1.1 0.0 1.5 121.5 0.3 0.0 0.4 2.1 0.2 0.0 6.8 2.0 2.5 0.0 0.0 0.1 0.0 0.5 0.0 0.3 0.8 0.1 1.6 0.0 0.4 RCC2 TD-60 ENSG00000179051 "Regulator of chromosome condensation 2" Q9P258 1 17406760-17439677 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072281 Approved NA NA 110000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA072281: AB_2686505" "unprognostic (2.50e-2)" "prognostic favorable (3.31e-4)" "unprognostic (9.91e-2)" "unprognostic (1.72e-1)" "unprognostic (2.74e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (3.42e-8)" "unprognostic (3.05e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (1.73e-1)" "unprognostic (1.31e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (4.03e-8)" "unprognostic (6.81e-3)" "unprognostic (2.09e-1)" "unprognostic (9.44e-2)" "unprognostic (4.41e-2)" 19.4 18.4 12.3 18.9 12.2 33.3 22.2 12.8 13.2 24.8 11.0 24.0 11.4 18.7 9.9 65.2 16.3 11.8 13.4 12.1 12.5 22.8 15.9 24.2 27.7 14.2 13.6 22.1 21.3 9.4 11.4 16.1 13.1 22.3 17.6 3.1 36.0 7.8 8.4 56.3 27.6 10.2 13.9 39.2 18.3 20.6 15.8 34.2 19.0 4.1 35.2 19.7 31.3 15.3 62.2 34.3 68.4 57.9 25.3 25.4 56.6 24.3 20.9 49.2 40.4 37.0 83.4 133.8 80.4 25.3 14.5 67.4 121.0 70.0 34.1 64.3 61.1 117.6 50.5 36.0 31.8 142.7 79.7 40.5 51.8 55.1 48.7 30.7 53.3 88.7 82.4 188.4 22.0 62.9 117.4 115.9 94.7 76.0 26.0 155.7 68.6 86.5 37.3 29.0 102.9 72.6 61.4 59.5 93.6 56.7 53.2 91.3 41.9 44.8 56.0 18.1 51.1 81.7 72.9 165.8 19.3 158.6 90.9 0.9 1.9 0.7 1.4 2.6 1.2 1.6 1.1 1.4 3.1 1.7 0.8 1.4 0.1 1.7 2.1 2.5 1.0 1.1 12.3 12.2 12.8 13.2 12.1 12.5 14.2 13.6 13.1 13.9 15.8 15.3 22.6 25.6 15.3 16.6 26.4 46.5 14.7 25.3 27.9 6.6 36.5 34.3 0.9 18.6 26.6 22.0 10.4 25.0 32.2 27.5 3.9 24.4 6.8 28.0 38.3 24.9 24.1 28.8 11.0 22.7 48.9 17.4 14.8 37.5 17.7 55.9 17.5 7.3 32.6 6.7 4.9 25.9 24.4 31.4 70.0 21.0 9.3 43.0 16.0 20.6 27.9 15.3 22.6 20.6 15.3 28.8 20.6 6.0 25.9 32.2 7.5 7.0 17.9 5.4 0.0 20.7 16.7 17.6 21.2 42.9 64.5 16.3 19.7 25.6 36.4 19.4 REEP4 "C8orf20, FLJ22246, FLJ22277, PP432, Yip2c" ENSG00000168476 "Receptor accessory protein 4" Q9H6H4 8 22138020-22141951 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 89.3;skin 1: 91.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042683 Approved Supported "Endoplasmic reticulum" No Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA042683: AB_2571730" "unprognostic (2.38e-1)" "unprognostic (9.96e-3)" "unprognostic (3.35e-2)" "unprognostic (2.38e-2)" "unprognostic (3.41e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.14e-5)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (7.15e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.88e-5)" "unprognostic (5.72e-2)" "unprognostic (1.06e-1)" "unprognostic (2.25e-1)" "unprognostic (6.65e-2)" 13.0 8.4 7.0 12.5 8.7 28.4 11.6 8.7 9.7 27.9 7.6 23.8 11.0 9.4 2.1 89.3 11.1 5.6 8.0 6.8 8.2 9.2 12.3 18.0 11.2 10.8 8.5 7.4 12.9 5.0 10.9 14.6 10.5 13.6 10.8 2.1 21.8 6.5 4.1 91.0 16.9 5.9 9.0 33.2 18.0 42.7 9.5 9.9 14.8 2.6 10.2 19.6 49.0 11.5 42.2 79.7 24.9 39.7 10.5 10.6 47.9 36.7 19.2 44.6 40.2 46.7 38.8 53.0 46.8 18.4 38.5 100.3 29.6 59.3 21.9 28.2 37.4 57.4 41.2 46.9 11.8 25.8 77.9 9.8 110.3 33.3 27.5 13.9 27.1 58.1 44.5 158.7 22.6 60.6 63.7 88.9 37.4 58.0 53.3 37.0 22.5 101.8 19.9 40.0 21.7 40.1 30.0 31.7 52.7 16.5 64.3 35.9 30.5 29.2 50.1 66.6 50.3 40.0 33.5 34.6 32.6 54.7 59.1 49.8 54.8 64.1 24.3 53.6 19.6 10.5 21.1 21.1 42.7 4.9 9.7 13.1 15.5 26.3 37.0 16.9 15.4 27.6 7.0 8.7 8.7 9.7 6.8 8.2 10.8 8.5 10.5 9.0 9.5 11.5 6.8 3.2 9.2 4.9 7.9 28.0 15.1 45.5 15.4 6.5 5.8 5.7 1.8 7.2 21.9 12.9 2.1 54.0 13.8 27.3 0.0 21.9 16.0 3.8 4.9 9.2 17.4 48.2 0.7 15.0 50.4 8.1 21.9 5.9 10.2 14.0 15.4 6.6 55.4 0.0 0.6 33.0 22.4 38.8 21.5 9.4 9.0 26.1 3.6 10.3 16.5 1.8 10.3 1.0 2.6 25.6 34.7 8.2 19.3 19.0 19.2 1.9 8.1 1.5 13.1 2.3 9.7 61.0 17.9 41.1 39.2 94.1 13.5 8.9 31.1 24.5 RFFL "CARP-2, CARP2, fring, rififylin, RNF189, RNF34L" ENSG00000092871 "Ring finger and FYVE like domain containing E3 ubiquitin protein ligase" Q8WZ73 17 35005990-35089319 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 93.8" "Cell type enhanced" "Detected in many" "Late spermatids: 109.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 119.5;Karpas-707: 112.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008096, HPA017910, HPA019492" Approved Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB008096: AB_2178607, HPA017910: AB_1856189, HPA019492: AB_1856190" "unprognostic (2.59e-1)" "unprognostic (2.87e-1)" "prognostic favorable (4.92e-4)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.79e-1)" "unprognostic (5.73e-3)" "unprognostic (4.34e-3)" "unprognostic (2.31e-1)" "unprognostic (9.26e-3)" "unprognostic (2.39e-1)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.44e-1)" "unprognostic (1.97e-1)" "unprognostic (8.68e-2)" "unprognostic (1.36e-1)" 9.9 7.1 23.9 17.7 59.5 41.4 12.2 49.2 38.0 11.9 11.6 26.7 28.1 9.6 8.8 35.9 9.3 19.4 8.2 24.3 36.4 17.7 48.3 12.6 17.6 74.2 53.0 8.5 18.8 12.1 6.8 11.9 71.2 18.3 23.2 21.1 13.1 12.7 15.8 7.5 22.8 13.3 48.6 19.2 23.3 26.6 52.2 26.0 39.0 13.1 29.4 20.3 16.2 93.8 22.9 43.4 10.7 15.0 21.6 28.1 6.1 15.6 25.8 15.5 18.7 15.4 50.5 7.0 19.4 21.4 33.0 32.2 18.4 30.8 22.4 119.5 11.2 40.5 11.0 38.6 18.0 20.2 20.0 19.0 18.8 23.7 46.9 22.6 15.6 21.2 18.2 112.2 16.0 8.7 4.9 19.4 15.2 51.1 24.9 17.3 18.7 43.2 22.8 48.6 12.0 15.8 8.9 10.3 9.1 24.4 15.9 27.7 29.7 8.6 14.9 8.7 24.1 41.4 33.0 9.4 36.4 15.8 7.4 28.6 16.2 33.7 16.8 9.3 20.6 7.8 18.5 16.3 10.8 6.9 16.0 14.5 55.3 14.4 9.9 1.3 29.6 15.5 23.9 59.5 49.2 38.0 24.3 36.4 74.2 53.0 71.2 48.6 52.2 93.8 6.5 41.7 27.4 0.0 12.6 6.0 11.9 7.4 5.2 10.6 9.9 3.8 1.3 20.0 17.3 0.0 14.6 9.4 12.1 33.7 1.9 8.4 41.0 13.0 6.8 6.6 15.0 23.8 0.0 15.1 1.7 9.3 23.0 18.1 25.3 5.4 9.3 35.2 7.2 6.7 0.0 26.4 6.1 16.3 16.9 109.1 3.1 16.1 1.8 0.0 22.6 20.8 25.7 0.0 0.0 16.8 19.3 4.5 12.9 28.1 16.7 20.4 11.7 34.9 6.6 15.2 5.7 15.9 10.8 16.2 6.1 5.1 23.7 3.1 18.9 39.5 RGS6 ENSG00000182732 "Regulator of G protein signaling 6" P49758 14 71932429-72566530 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.2" "Cell type enhanced" "Detected in many" "Astrocytes: 97.3;Early spermatids: 173.5;Excitatory neurons: 652.7;Inhibitory neurons: 256.1;Late spermatids: 298.0" "Group enriched" "Detected in some" 7 "glioma: 3.1;thyroid cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 11.5;Karpas-707: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003067 Uncertain Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Vesicles" "HPA003067: AB_1079807" "unprognostic (7.18e-2)" "unprognostic (7.78e-2)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (5.61e-2)" "unprognostic (3.80e-2)" "unprognostic (1.24e-4)" "unprognostic (7.83e-2)" "unprognostic (2.03e-1)" "unprognostic (8.17e-2)" "unprognostic (1.30e-1)" "unprognostic (2.06e-2)" "unprognostic (8.64e-2)" "unprognostic (5.11e-2)" "unprognostic (8.06e-3)" "unprognostic (2.10e-1)" "unprognostic (3.68e-2)" 4.7 0.2 1.1 0.6 2.2 1.4 4.0 0.6 8.6 4.9 0.0 1.0 0.3 1.4 2.6 0.4 2.2 1.2 11.2 3.5 2.8 2.6 0.1 0.9 0.1 19.2 16.0 1.2 0.2 8.1 1.7 3.0 20.2 0.4 1.0 1.7 0.8 1.4 1.1 0.9 0.8 1.3 5.4 0.9 0.4 10.6 6.4 0.3 5.7 0.8 0.5 0.7 0.9 3.4 0.0 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 11.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 40.1 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.5 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.3 1.2 1.1 2.2 0.6 8.6 3.5 2.8 19.2 16.0 20.2 5.4 6.4 3.4 5.8 0.0 0.0 97.3 0.2 0.3 0.0 0.0 0.0 2.2 2.1 2.4 22.6 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 173.5 2.8 0.9 2.6 0.0 5.3 652.7 0.2 0.1 3.1 0.0 7.1 0.0 0.4 0.0 0.0 0.2 0.0 256.1 0.0 0.0 0.0 0.0 298.0 1.8 8.3 0.0 44.0 5.1 0.0 0.0 36.2 8.9 0.0 0.0 7.5 0.2 0.0 0.0 0.4 0.0 0.4 13.1 0.4 18.6 2.3 1.3 0.2 0.1 0.8 0.5 0.1 0.0 0.7 RINL FLJ45909 ENSG00000187994 "Ras and Rab interactor like" Q6ZS11 19 38867830-38878275 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 32.5;NK-cells: 45.3;Skeletal myocytes: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 14.2;Karpas-707: 24.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042083, HPA042103" Uncertain Approved Nucleoplasm,Vesicles No No "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Vesicles" "HPA042083: AB_10793977, HPA042103: AB_10797380" "unprognostic (1.30e-1)" "prognostic favorable (6.49e-5)" "unprognostic (7.38e-2)" "unprognostic (1.75e-2)" "unprognostic (6.05e-2)" "prognostic favorable (1.64e-4)" "unprognostic (2.61e-2)" "unprognostic (3.64e-2)" "unprognostic (4.87e-2)" "unprognostic (5.95e-2)" "unprognostic (1.85e-1)" "unprognostic (7.90e-2)" "unprognostic (3.18e-1)" "unprognostic (1.75e-1)" "unprognostic (1.89e-1)" "unprognostic (3.17e-2)" "unprognostic (6.40e-3)" 5.3 2.5 2.2 5.3 2.7 2.8 4.2 2.6 2.8 2.8 2.9 3.9 1.6 2.0 0.9 6.3 3.3 1.7 3.5 2.1 2.3 6.1 7.8 4.3 9.7 2.6 2.1 1.5 13.2 2.7 7.2 1.6 2.9 2.5 1.4 2.5 5.3 1.1 2.3 3.6 8.4 1.0 1.9 15.8 4.2 1.1 2.2 3.9 5.1 0.9 7.6 4.6 3.7 2.2 0.0 1.8 0.4 0.2 0.7 0.3 2.8 0.4 0.3 0.4 0.4 1.9 9.2 9.1 3.1 0.4 0.1 0.2 1.7 2.4 0.5 1.7 0.6 10.1 2.6 4.8 1.9 6.4 14.2 2.0 0.4 1.2 0.5 0.3 3.5 5.1 1.8 24.6 0.0 1.6 1.6 4.3 0.8 5.2 0.3 1.2 0.1 6.5 1.7 0.2 3.2 1.3 4.2 6.7 3.6 0.4 0.8 7.7 2.6 0.1 1.9 0.5 0.1 9.1 9.3 6.3 0.7 2.8 0.5 5.3 1.1 1.6 10.3 2.5 6.5 17.4 6.9 7.7 2.0 21.9 5.3 6.4 3.0 5.2 2.5 16.0 8.1 3.6 2.2 2.7 2.6 2.8 2.1 2.3 2.6 2.1 2.9 1.9 2.2 2.2 6.7 3.2 7.7 0.0 22.4 3.2 5.3 2.9 4.6 4.0 5.8 4.7 3.5 8.6 2.3 3.7 8.4 13.9 32.5 0.6 7.9 7.3 0.5 2.8 1.6 6.9 7.2 9.0 2.2 7.3 7.1 4.3 5.1 6.3 15.2 1.3 8.2 7.5 9.3 0.0 1.6 0.7 14.2 6.8 2.7 1.3 3.1 4.3 10.6 1.0 10.5 6.2 45.3 3.5 0.6 5.1 1.7 2.6 14.8 2.3 0.6 12.7 1.3 10.6 0.0 30.3 2.3 2.7 4.4 6.4 3.8 4.1 24.6 5.0 1.3 3.6 RNF148 MGC35222 ENSG00000235631 "Ring finger protein 148" Q8N7C7 7 122701668-122702922 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 49.3" "Cell type enriched" "Detected in some" 6 "Early spermatids: 405.2" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "cerebellum: 9.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.8;MCF7: 1.1" "Not detected" "Not detected" HPA045587 Approved Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA045587: AB_10963695" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (3.19e-1)" "unprognostic (1.21e-2)" "unprognostic (2.85e-1)" "unprognostic (3.23e-2)" "unprognostic (1.04e-2)" "unprognostic (9.81e-2)" "unprognostic (8.48e-2)" "unprognostic (2.14e-2)" "unprognostic (2.18e-1)" "unprognostic (2.37e-1)" "unprognostic (3.33e-2)" "unprognostic (2.24e-2)" "unprognostic (1.24e-1)" "unprognostic (6.63e-2)" "unprognostic (1.09e-1)" 0.2 0.2 0.0 0.0 0.2 0.0 0.2 9.9 1.7 0.2 0.2 0.1 0.0 0.6 0.1 0.0 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.4 0.0 0.0 0.2 0.1 0.3 0.0 0.2 0.0 0.6 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 49.3 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 2.8 0.0 1.1 0.0 0.0 0.3 0.6 0.3 0.0 0.0 0.7 0.0 0.2 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 9.9 1.7 0.2 0.1 0.0 0.2 0.6 0.0 0.1 0.7 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.1 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 405.2 0.5 0.5 0.5 0.0 0.0 0.0 1.0 0.1 0.1 0.0 0.8 0.0 0.1 1.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 62.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 1.9 0.0 0.1 0.0 0.2 0.0 0.0 6.6 0.2 0.1 3.9 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved Approved "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "Mitotic spindle, Centriolar satellite" "HPA049810: AB_2680894" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favorable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favorable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" 75.0 110.6 141.9 53.0 146.7 69.0 73.1 146.4 179.9 93.2 138.6 111.5 66.6 94.9 76.4 122.1 84.3 45.3 131.8 141.5 146.4 106.7 184.2 77.5 64.5 146.3 145.4 87.4 115.1 105.8 96.8 50.7 146.3 95.0 65.7 98.1 92.5 70.5 152.9 127.8 100.5 52.8 142.4 113.8 111.8 110.6 150.3 98.1 93.4 94.2 71.6 106.7 90.4 153.3 102.6 143.1 61.1 73.7 132.8 68.7 92.7 63.4 76.1 119.7 93.4 96.2 43.3 71.5 120.3 93.5 63.9 147.5 103.2 114.8 86.1 74.5 166.1 121.9 164.4 94.9 100.6 59.0 245.0 79.6 176.5 129.8 116.2 74.6 77.2 101.0 49.9 237.5 96.2 66.3 92.8 70.6 75.4 102.0 86.8 62.8 61.9 91.5 137.3 77.4 49.2 61.1 56.0 92.9 81.9 83.1 87.3 55.9 49.5 76.6 48.3 66.8 119.3 79.5 88.0 23.7 98.4 80.6 77.9 108.4 88.8 236.9 195.3 94.0 153.4 100.4 148.0 195.7 73.9 98.7 103.2 152.2 219.8 118.8 117.7 75.9 153.0 177.0 141.9 146.7 146.4 179.9 141.5 146.4 146.3 145.4 146.3 142.4 150.3 153.3 36.9 0.0 3.9 12.4 54.3 68.6 44.4 65.8 51.8 43.2 56.6 44.7 15.8 77.2 38.9 49.7 20.9 120.1 64.7 65.2 56.7 78.5 59.6 29.8 25.1 36.4 31.8 60.6 11.3 66.7 139.7 36.3 36.2 32.2 14.0 26.3 45.7 95.1 58.4 18.5 11.2 45.7 65.1 41.3 43.6 86.5 48.7 36.1 39.2 6.5 53.1 46.9 114.4 10.1 17.9 60.7 44.9 53.8 59.1 32.6 108.2 64.0 31.1 32.3 39.5 28.4 35.1 127.1 106.7 61.4 83.3 125.2 82.5 37.2 59.6 48.0 RNF19A "DKFZp566B1346, dorfin, RNF19" ENSG00000034677 "Ring finger protein 19A, RBR E3 ubiquitin protein ligase" Q9NV58 8 100257060-100336218 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 178.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011455, HPA023652" Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB011455: AB_2180446, HPA023652: AB_1847836" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.84e-1)" "unprognostic (7.09e-2)" "unprognostic (3.36e-1)" "unprognostic (2.12e-2)" "unprognostic (7.96e-2)" "unprognostic (8.92e-2)" "unprognostic (1.13e-1)" "unprognostic (5.97e-2)" "unprognostic (5.20e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (8.44e-2)" "unprognostic (8.19e-2)" "unprognostic (2.02e-1)" "prognostic favorable (3.28e-5)" 32.0 18.8 29.1 32.7 28.7 57.4 28.6 22.7 25.5 52.0 17.6 25.9 24.0 41.3 16.4 21.6 30.5 43.1 25.0 25.3 48.3 30.0 49.3 34.7 55.4 40.2 36.0 27.4 25.9 16.1 15.2 26.9 33.0 22.0 26.5 27.2 22.3 18.7 28.0 31.8 37.9 32.6 37.3 31.5 27.4 53.0 36.1 34.3 18.8 31.0 43.8 35.9 27.3 40.7 26.7 16.9 14.8 16.9 27.7 23.1 18.7 23.4 22.5 22.0 19.9 9.0 17.3 15.7 41.6 24.7 10.2 18.9 11.6 17.4 29.6 65.3 9.4 26.1 86.8 13.5 22.8 5.3 15.6 23.3 26.1 17.5 33.1 26.9 34.3 17.3 14.8 178.6 21.8 13.5 24.6 9.0 5.4 18.2 15.5 9.8 10.0 30.7 60.2 41.7 11.4 24.6 24.5 14.9 23.3 30.6 13.1 20.5 33.9 25.3 19.9 18.7 14.3 85.5 59.3 10.4 16.2 17.4 15.4 26.3 8.6 8.1 16.3 6.8 10.4 15.5 13.4 12.6 5.7 13.9 6.9 9.8 19.6 6.2 14.2 14.1 14.7 5.8 29.1 28.7 22.7 25.5 25.3 48.3 40.2 36.0 33.0 37.3 36.1 40.7 70.8 51.3 51.6 106.7 101.7 40.1 83.4 56.9 18.8 29.9 44.7 32.5 40.6 110.1 83.6 44.1 60.5 11.0 184.8 61.6 7.9 65.0 183.8 165.9 78.2 66.3 20.8 124.8 76.9 40.2 14.5 62.5 67.8 242.1 43.0 172.0 32.2 42.9 23.0 58.9 69.7 25.9 42.7 30.5 41.8 259.4 58.4 39.2 21.4 73.1 24.1 43.5 65.9 35.7 39.9 49.0 32.0 68.8 161.7 66.3 50.9 54.1 106.2 48.4 19.7 77.4 46.3 77.8 47.2 26.1 60.4 8.2 204.6 46.3 21.8 144.9 RNF19B "FLJ90005, IBRDC3" ENSG00000116514 "Ring finger protein 19B" Q6ZMZ0 1 32936445-32964809 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 79.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.9" "Lineage enriched" "Detected in all" 8 "granulocytes: 16.9" "Cell line enhanced" "Detected in all" "Daudi: 107.6;Karpas-707: 124.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049587, HPA063640" Approved Approved Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA049587: AB_2680826, HPA063640: " "unprognostic (2.83e-2)" "unprognostic (1.77e-2)" "unprognostic (1.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "prognostic favorable (3.39e-4)" "prognostic unfavorable (5.41e-6)" "unprognostic (8.78e-2)" "unprognostic (5.02e-1)" "unprognostic (1.69e-1)" "unprognostic (9.85e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.39e-5)" "unprognostic (2.58e-2)" "unprognostic (4.93e-2)" "unprognostic (3.30e-1)" "unprognostic (1.23e-2)" 14.5 19.1 10.7 24.3 9.6 74.1 10.9 14.5 10.7 16.8 7.6 23.3 25.0 15.0 5.0 35.3 12.3 17.4 10.4 9.9 12.1 21.1 11.3 21.1 17.7 10.7 9.6 9.7 9.2 11.5 7.9 14.9 11.8 11.0 25.8 18.9 15.4 8.9 16.2 22.6 21.7 18.0 11.6 15.1 13.1 79.0 10.8 13.0 9.0 11.1 30.6 30.1 20.9 11.6 18.7 14.3 11.9 11.3 7.1 9.6 79.5 8.5 10.0 14.7 15.6 16.8 54.9 107.6 14.2 10.7 18.2 26.5 14.3 19.8 13.3 39.6 9.5 9.2 10.5 16.9 22.5 14.7 19.0 7.9 36.3 32.5 39.3 17.2 31.9 10.3 11.7 124.8 14.5 6.1 9.6 18.4 19.2 21.1 15.8 12.7 17.3 11.3 11.5 26.4 18.9 9.6 27.0 9.1 63.1 29.1 8.0 20.8 35.1 8.1 11.5 21.1 15.1 29.6 16.1 38.0 11.9 14.7 12.5 6.1 2.0 4.0 1.6 1.9 1.3 1.2 1.4 0.7 1.4 1.5 0.4 0.6 16.9 1.0 1.7 0.6 1.7 0.8 10.7 9.6 14.5 10.7 9.9 12.1 10.7 9.6 11.8 11.6 10.8 11.6 20.6 12.8 4.4 5.5 8.7 46.1 27.0 26.7 24.5 4.6 15.8 11.7 16.2 10.0 9.9 7.3 2.1 12.6 14.6 48.0 1.9 12.9 34.8 25.4 7.3 15.3 11.3 5.2 9.7 11.5 6.3 8.4 13.3 36.9 4.5 3.2 7.1 4.8 13.5 3.3 9.8 22.1 6.1 20.9 37.7 26.3 2.1 42.4 5.4 19.7 39.5 2.8 2.1 7.5 6.6 25.7 31.9 3.8 4.6 34.2 38.6 9.2 14.4 7.7 0.0 5.9 9.6 34.7 16.3 23.9 32.5 7.4 10.3 2.3 16.3 41.7 RO60 "SSA2, TROVE2" ENSG00000116747 "Ro60, Y RNA binding protein" P10155 1 193059454-193091777 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 53.0;Cardiomyocytes: 53.0;Cytotrophoblasts: 47.1;dendritic cells: 41.3;Extravillous trophoblasts: 45.2;Hofbauer cells: 33.4;Syncytiotrophoblasts: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002835 Uncertain Supported Cytosol NA NA 50000 "Cluster 34: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA002835: AB_1857490" "unprognostic (1.91e-2)" "unprognostic (5.11e-2)" "unprognostic (3.94e-3)" "unprognostic (7.34e-2)" "unprognostic (2.34e-2)" "unprognostic (1.41e-1)" "unprognostic (3.62e-2)" "unprognostic (1.17e-1)" "unprognostic (3.77e-2)" "unprognostic (1.16e-2)" "unprognostic (8.45e-3)" "unprognostic (1.52e-1)" "unprognostic (1.05e-3)" "unprognostic (6.32e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (3.31e-4)" "unprognostic (5.62e-2)" 10.8 8.3 10.6 8.8 16.4 29.7 8.1 15.5 8.7 7.3 3.9 7.5 6.0 9.5 6.4 9.5 6.5 7.4 10.0 6.8 13.9 7.4 9.3 7.6 9.8 17.7 12.8 10.0 7.5 7.0 4.7 8.7 18.6 8.8 6.1 15.4 6.9 6.1 9.9 7.6 6.4 9.4 15.9 10.0 6.4 13.0 11.1 8.2 9.7 10.2 8.9 8.4 7.5 22.6 13.4 25.5 22.5 25.2 20.0 17.7 15.9 19.5 19.8 14.8 18.9 11.8 18.0 25.1 15.7 18.4 14.5 18.7 19.0 13.3 23.2 40.7 14.4 31.4 22.2 15.6 16.5 35.4 23.4 15.9 13.2 25.4 25.1 11.4 19.4 11.5 34.7 38.0 20.3 26.6 21.1 9.3 16.1 10.2 10.8 18.2 21.1 30.7 11.8 28.0 9.4 17.6 25.0 24.8 25.0 15.3 24.2 14.4 26.8 26.0 11.4 25.7 25.8 20.5 29.0 26.8 11.8 18.1 38.9 102.1 31.6 46.0 53.4 29.9 52.3 47.7 37.2 47.0 32.4 44.6 39.6 45.2 53.9 45.2 33.2 29.1 44.7 39.8 10.6 16.4 15.5 8.7 6.8 13.9 17.7 12.8 18.6 15.9 11.1 22.6 53.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.0 0.0 0.0 0.0 0.0 47.1 41.3 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 45.2 17.8 0.0 0.0 0.0 0.0 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 48.0 6.2 0.0 0.0 0.0 RORA "NR1F1, ROR1, ROR2, ROR3, RZRA" ENSG00000069667 "RAR related orphan receptor A" P35398 15 60488284-61229302 "Disease related genes, Human disease related genes, Metabolic proteins, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Receptor" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 82.8" "Cell type enhanced" "Detected in many" "Astrocytes: 2125.3;Excitatory neurons: 627.1;Inhibitory neurons: 1056.8;Microglial cells: 757.0;Oligodendrocyte precursor cells: 1524.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in many" 4 "T-cells: 26.7" "Cell line enhanced" "Detected in many" "Karpas-707: 73.2;U-266/70: 41.7;U-266/84: 62.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009861, HPA074448" Approved Supported Nucleoli NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoli "CAB009861: AB_2180141, HPA074448: " "unprognostic (1.57e-1)" "unprognostic (4.76e-2)" "unprognostic (2.22e-1)" "unprognostic (2.92e-2)" "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" "unprognostic (2.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.02e-2)" "unprognostic (1.13e-1)" "unprognostic (9.93e-2)" "unprognostic (1.34e-1)" "prognostic favorable (5.42e-6)" "unprognostic (6.94e-2)" "unprognostic (1.35e-1)" "unprognostic (2.55e-1)" "unprognostic (4.62e-2)" 8.2 38.0 19.9 6.2 11.7 17.5 13.6 51.1 13.1 10.5 10.2 6.9 2.6 6.0 4.7 17.3 6.8 9.1 7.2 3.7 12.6 12.6 28.7 11.2 6.2 7.8 36.0 9.9 14.0 10.1 7.6 2.9 5.9 5.7 3.5 37.8 8.5 5.5 41.4 82.8 6.3 5.4 4.5 9.3 6.2 13.9 49.6 4.3 12.8 20.3 7.5 5.2 9.2 4.2 0.1 0.8 2.7 0.0 3.4 1.7 0.9 1.3 1.5 1.2 1.4 1.8 0.5 0.0 0.6 3.4 3.6 0.5 6.1 2.6 2.2 2.9 5.2 0.0 0.4 2.9 1.3 0.0 0.3 7.8 0.6 3.3 0.0 1.1 11.6 11.2 0.2 73.2 5.1 0.2 0.6 0.0 2.1 1.9 1.1 0.1 2.4 1.1 2.4 0.5 1.9 4.4 0.3 0.6 0.1 7.3 0.0 0.0 0.3 10.1 4.5 4.2 0.1 41.7 62.1 0.2 17.0 0.0 1.2 0.2 0.1 0.0 23.2 0.0 26.7 1.4 17.4 16.0 0.0 0.1 5.4 11.5 0.5 6.5 0.1 0.7 16.3 4.7 19.9 11.7 51.1 13.1 3.7 12.6 7.8 36.0 5.9 4.5 49.6 4.2 32.5 41.7 31.7 2125.3 23.4 185.2 30.1 17.0 55.2 167.5 24.7 16.1 26.3 30.0 23.4 58.8 454.5 0.7 185.3 1.4 13.7 21.4 148.8 26.9 52.9 40.8 18.5 42.5 627.1 12.3 1.9 69.4 11.7 36.1 2.5 7.9 34.2 97.2 0.8 126.2 1056.8 3.3 10.2 9.1 35.8 97.1 46.6 8.3 60.5 757.0 4.7 50.4 250.3 1524.0 114.9 8.2 0.5 87.3 88.7 24.0 0.7 44.6 16.0 160.0 39.5 57.9 32.2 1.9 3.8 73.2 423.4 4.7 237.6 11.5 2.1 61.9 RSRP1 "C1orf63, DJ465N24.2.1" ENSG00000117616 "Arginine and serine rich protein 1" Q9BUV0 1 25242249-25338213 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 49.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058992, HPA067651" Uncertain Approved Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA058992: AB_2683873, HPA067651: AB_2685879" "unprognostic (1.03e-1)" "unprognostic (4.52e-2)" "unprognostic (2.18e-1)" "unprognostic (7.24e-2)" "unprognostic (3.65e-2)" "unprognostic (3.81e-2)" "unprognostic (5.77e-3)" "unprognostic (3.67e-2)" "unprognostic (2.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.02e-2)" "unprognostic (7.51e-3)" "unprognostic (1.73e-3)" "unprognostic (4.84e-2)" "unprognostic (1.87e-1)" "unprognostic (7.87e-2)" "prognostic favorable (2.91e-5)" 31.1 31.2 19.6 3.5 27.1 12.8 18.6 25.7 29.4 54.5 25.8 34.0 4.7 29.6 4.4 39.3 38.9 16.3 42.9 20.7 18.1 53.5 35.1 42.4 5.8 37.3 23.6 47.8 19.6 0.9 59.9 8.8 26.0 56.3 2.0 8.5 39.1 18.2 18.8 22.4 26.0 2.1 22.9 37.6 27.2 24.4 25.0 24.4 41.3 21.2 11.4 33.4 52.7 34.8 7.7 16.8 2.2 2.4 18.3 2.7 6.6 7.1 1.3 8.2 9.2 13.7 8.5 6.1 23.0 1.0 3.0 11.4 14.7 1.3 2.8 14.4 8.9 21.0 20.5 17.9 3.9 9.7 11.3 1.8 8.9 3.8 0.0 3.2 4.8 6.3 17.7 49.9 2.3 7.6 2.2 18.5 9.1 17.1 9.7 9.2 6.9 9.1 6.1 0.3 8.9 1.9 4.7 4.7 5.1 1.4 3.9 10.6 10.7 5.7 5.6 5.0 4.1 29.1 24.0 6.3 4.3 24.1 4.5 149.6 57.0 87.4 25.5 38.0 26.7 24.8 26.8 21.6 60.4 23.5 25.3 17.3 130.4 36.6 54.5 37.9 37.6 30.9 19.6 27.1 25.7 29.4 20.7 18.1 37.3 23.6 26.0 22.9 25.0 34.8 351.6 60.9 77.0 121.1 332.7 0.0 229.7 0.0 338.6 86.9 200.1 217.0 47.7 45.8 37.8 93.8 141.8 80.3 456.5 385.9 21.5 43.0 29.8 115.2 142.0 150.0 130.6 140.9 172.6 21.1 82.8 169.0 183.0 146.4 217.1 140.1 71.4 19.6 61.9 84.1 125.4 200.1 0.0 72.2 0.0 16.5 140.1 197.5 0.0 140.5 160.6 69.3 200.8 93.0 278.8 43.6 340.3 90.3 248.4 130.3 397.9 15.2 59.0 138.8 124.9 214.1 141.8 107.6 102.8 283.0 0.0 121.2 346.7 123.8 159.6 196.8 RUBCN "KIAA0226, rubicon, rundataxin" ENSG00000145016 "Rubicon autophagy regulator" Q92622 3 197668867-197749727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Endocytosis, Immunity, Phagocytosis" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 67.5;Plasma cells: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 87.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050908, HPA054497" Approved Supported Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Vesicles, Cytosol" "HPA050908: , HPA054497: AB_2682507" "unprognostic (2.91e-2)" "unprognostic (1.61e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (1.34e-3)" "unprognostic (1.46e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (9.91e-5)" "unprognostic (1.99e-1)" "unprognostic (6.71e-2)" "unprognostic (2.86e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (2.22e-2)" "unprognostic (2.92e-2)" "unprognostic (1.75e-1)" "unprognostic (2.43e-1)" "unprognostic (1.23e-1)" 8.3 7.5 16.2 11.6 16.3 8.5 7.2 10.5 17.0 9.2 4.4 10.4 7.3 8.8 4.0 12.0 8.5 7.2 11.4 17.0 19.0 7.7 5.6 11.8 15.3 20.0 17.8 10.7 9.1 6.8 15.8 5.8 15.9 7.4 5.7 10.9 7.3 7.2 8.9 9.1 13.1 7.8 14.5 19.2 8.1 14.6 23.7 8.8 7.1 8.1 16.1 8.9 8.4 17.4 30.9 7.4 8.2 16.2 14.4 8.3 8.6 13.8 9.2 17.0 14.2 12.7 8.4 33.6 26.7 15.8 16.1 17.0 15.0 8.0 13.6 9.3 13.9 21.6 13.4 4.9 8.4 12.0 18.0 7.0 9.6 14.8 17.6 7.9 10.7 14.4 12.3 87.7 11.5 24.4 15.7 7.5 7.1 8.8 23.2 14.9 8.6 22.6 9.6 13.9 34.3 7.9 10.2 19.8 10.8 5.5 29.2 8.1 13.7 9.9 9.9 27.8 18.9 36.5 34.2 27.0 13.6 22.4 8.7 0.8 2.6 17.5 3.7 3.9 2.4 7.7 3.1 4.7 1.6 8.5 2.2 3.2 2.9 1.8 4.8 16.6 4.4 1.7 16.2 16.3 10.5 17.0 17.0 19.0 20.0 17.8 15.9 14.5 23.7 17.4 8.5 6.4 11.2 0.0 33.9 0.0 6.0 0.0 8.0 21.0 7.3 7.0 0.0 7.2 4.3 12.9 18.8 1.8 28.9 3.8 1.9 5.8 21.7 4.8 6.2 6.7 0.0 5.7 0.0 6.4 3.7 4.8 7.1 9.8 2.5 6.1 9.3 3.5 9.2 21.9 0.0 3.7 0.0 16.3 0.0 16.4 5.0 18.7 0.0 0.0 67.5 15.0 14.4 0.0 0.0 8.5 1.5 6.4 48.3 8.9 5.8 2.7 0.7 14.3 6.6 9.7 6.8 34.1 21.3 5.6 0.0 6.4 15.9 4.9 2.8 12.3 RUFY4 "FLJ46536, ZFYVE31" ENSG00000188282 "RUN and FYVE domain containing 4" Q6ZNE9 2 218034960-218090581 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;lymphoid tissue: 2.2" "Group enriched" "Detected in some" 4 "Granulosa cells: 9.5;Langerhans cells: 4.0;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "Karpas-707: 10.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA037980 Uncertain NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA037980: AB_10672501" "unprognostic (1.27e-3)" "unprognostic (4.60e-3)" "unprognostic (9.39e-3)" "unprognostic (6.79e-2)" "unprognostic (5.92e-2)" "unprognostic (6.57e-3)" "unprognostic (1.16e-1)" "unprognostic (2.42e-2)" "unprognostic (1.31e-3)" "unprognostic (1.50e-1)" "unprognostic (6.09e-2)" "unprognostic (1.55e-1)" "unprognostic (2.41e-14)" "unprognostic (1.36e-2)" "unprognostic (1.13e-3)" "unprognostic (3.45e-1)" "unprognostic (1.43e-5)" 0.1 0.2 0.5 0.9 0.6 0.8 0.1 0.4 1.8 0.1 0.4 0.2 0.7 0.0 0.0 0.4 0.2 0.5 0.0 0.9 0.4 0.1 0.2 0.4 1.1 0.4 0.4 0.1 0.0 0.0 0.1 0.0 0.4 1.1 0.5 0.1 0.5 0.1 0.0 0.3 0.7 0.0 0.5 2.2 0.6 0.1 0.4 1.7 0.1 0.0 0.8 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.4 1.8 0.9 0.4 0.4 0.4 0.4 0.5 0.4 0.4 0.0 0.0 0.0 2.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 9.5 0.0 0.0 0.2 0.0 0.2 0.0 0.0 1.3 4.0 0.3 0.0 0.9 0.0 1.0 2.0 0.0 0.0 13.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 RUNX3 "AML2, CBFA3, PEBP2A3" ENSG00000020633 "RUNX family transcription factor 3" Q13761 1 24899511-24965121 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.8;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "dendritic cells: 336.4;Langerhans cells: 133.9;NK-cells: 251.3;Plasma cells: 87.1;T-cells: 215.4" "Cancer enhanced" "Detected in all" "melanoma: 25.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 124.9;Karpas-707: 155.6;SK-MEL-30: 92.4;U-266/70: 54.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004195, CAB025416, HPA059006" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" Cytosol "CAB025416: , HPA004195: , HPA059006: AB_2683877" "unprognostic (7.75e-3)" "unprognostic (6.51e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.42e-1)" "unprognostic (7.60e-2)" "unprognostic (1.81e-2)" "unprognostic (6.51e-2)" "unprognostic (6.95e-2)" "unprognostic (3.39e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "prognostic unfavorable (5.59e-5)" "unprognostic (1.10e-1)" "unprognostic (4.42e-2)" "unprognostic (3.08e-1)" "unprognostic (1.62e-1)" 3.5 1.4 3.7 21.1 3.6 68.8 3.5 3.8 4.6 19.7 3.7 3.7 5.0 1.6 0.7 2.6 1.6 5.3 1.1 3.6 3.8 1.6 3.7 9.5 34.7 4.7 4.4 0.6 0.9 0.4 0.7 0.9 4.3 1.9 4.2 0.1 4.7 0.8 3.8 11.5 15.0 1.6 4.1 35.1 5.5 2.3 4.3 11.2 1.8 0.7 29.0 6.5 1.5 4.5 0.3 10.4 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.5 0.0 0.5 0.0 19.3 18.4 16.4 0.1 0.4 11.1 0.0 0.7 124.9 1.9 0.4 1.8 0.1 0.0 4.5 42.8 0.1 0.0 0.0 1.1 0.0 0.0 3.1 0.1 155.6 0.0 0.0 1.5 37.9 0.7 0.0 3.2 0.0 0.1 22.7 0.0 0.5 3.5 0.0 7.3 0.1 92.4 2.9 0.0 25.7 0.0 0.0 1.9 0.0 0.5 54.6 40.4 18.2 0.1 42.0 4.4 0.7 1.1 7.0 21.7 4.5 11.3 6.7 7.9 18.7 1.4 5.7 3.9 14.6 1.3 28.7 7.7 1.5 9.2 5.5 3.7 3.6 3.8 4.6 3.6 3.8 4.7 4.4 4.3 4.1 4.3 4.5 4.4 0.0 3.6 0.0 57.7 7.6 0.8 4.6 2.2 0.0 9.8 11.3 2.4 0.0 1.5 1.8 0.0 0.1 336.4 0.5 0.0 0.2 2.3 1.1 1.2 2.4 0.0 13.7 0.0 0.2 0.1 3.3 13.3 2.3 45.2 0.0 2.2 1.5 4.6 0.0 0.0 0.5 0.0 22.9 133.9 1.0 0.0 55.6 46.2 1.0 51.1 0.0 251.3 0.0 0.1 0.1 0.1 0.7 87.1 1.2 0.0 0.3 0.5 0.0 0.0 3.5 3.6 0.3 4.1 2.3 5.8 0.3 215.4 0.1 0.4 0.4 SAGE1 "CT14, SAGE" ENSG00000181433 "Sarcoma antigen 1" Q9NXZ1 X 135889205-135913061 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 4.8" "Cell type enriched" "Detected in some" 9 "Spermatogonia: 9.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 20.5;K-562: 15.6;Karpas-707: 25.5;U-2 OS: 7.0;U-266/70: 8.9;U-266/84: 23.8" "HPA003033, HPA003208" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA003033: AB_1079865, HPA003208: AB_1079863" "unprognostic (1.11e-1)" "unprognostic (5.26e-2)" "unprognostic (1.15e-1)" "unprognostic (1.02e-2)" "unprognostic (2.37e-1)" "unprognostic (7.12e-4)" "unprognostic (1.45e-2)" "unprognostic (1.10e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 25.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 8.9 23.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.3 0.4 0.5 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SAMD9L "C7orf6, FLJ39885, KIAA2005" ENSG00000177409 "Sterile alpha motif domain containing 9 like" Q8IVG5 7 93130056-93148385 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 38.3" "Cell type enhanced" "Detected in many" "monocytes: 64.8;NK-cells: 91.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 54.0;GAMG: 44.1;HDLM-2: 51.2;Karpas-707: 131.4" "Low region specificity" "Detected in all" "HPA019461, HPA019465, HPA019488" Enhanced Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA019461: AB_1856555, HPA019465: AB_2183384, HPA019488: AB_1856557" "unprognostic (6.93e-3)" "unprognostic (6.12e-2)" "unprognostic (5.00e-2)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (5.03e-2)" "unprognostic (7.10e-2)" "unprognostic (4.21e-2)" "unprognostic (2.32e-1)" "unprognostic (6.18e-3)" "unprognostic (1.05e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.63e-5)" "unprognostic (1.36e-1)" "unprognostic (2.07e-2)" "unprognostic (1.85e-2)" "unprognostic (1.22e-1)" 10.2 6.0 4.0 24.4 4.6 10.0 7.5 3.6 4.4 7.2 3.7 10.5 11.5 7.3 4.5 6.3 6.5 13.8 6.2 3.6 4.9 6.8 6.1 21.9 27.1 9.5 4.5 9.1 3.2 1.9 3.9 12.6 5.9 4.3 11.4 2.4 12.9 4.2 2.9 4.1 11.7 9.1 8.0 38.3 14.4 2.9 5.4 22.9 6.7 4.6 16.2 11.9 6.3 6.3 7.2 0.4 0.0 0.4 9.3 18.7 0.2 6.2 25.7 34.5 54.0 0.0 15.9 4.7 7.7 16.7 44.1 3.1 0.0 2.2 5.5 51.2 0.0 4.3 1.9 0.0 7.5 9.6 7.0 7.2 0.8 6.9 1.0 6.4 15.1 7.1 0.0 131.4 14.6 0.0 15.3 8.5 0.5 0.0 1.8 6.3 2.2 11.0 1.8 0.6 0.0 0.3 1.3 0.2 9.8 0.1 0.4 5.0 35.8 10.1 2.2 29.6 3.8 36.4 13.0 1.3 10.6 8.6 10.1 30.1 6.7 16.7 13.4 13.3 11.6 15.1 7.4 10.0 6.3 10.3 4.3 7.7 29.2 8.2 12.8 4.7 11.8 4.0 4.0 4.6 3.6 4.4 3.6 4.9 9.5 4.5 5.9 8.0 5.4 6.3 37.4 35.3 11.2 15.7 28.5 2.3 2.3 6.0 4.6 0.0 8.0 5.5 1.8 2.8 9.6 11.0 0.0 0.3 34.2 18.8 9.8 12.7 0.1 4.9 16.3 28.0 1.2 10.1 0.2 5.7 1.0 14.3 20.4 2.4 34.2 12.2 27.5 0.4 24.4 0.0 0.1 12.6 6.1 20.4 12.9 1.1 9.6 36.5 7.2 44.0 64.8 14.1 91.6 0.0 0.2 16.2 50.2 11.7 28.1 3.1 5.1 4.2 18.6 0.4 6.6 15.0 7.7 0.3 0.2 4.1 2.3 0.1 34.0 12.2 4.1 8.0 SAP30 ENSG00000164105 "Sin3A associated protein 30" O75446 4 173369969-173377532 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 77.2;Macrophages: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022627, HPA059012" Enhanced Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB022627: , HPA059012: AB_2683880" "unprognostic (1.53e-1)" "unprognostic (3.67e-2)" "unprognostic (3.26e-1)" "unprognostic (1.39e-1)" "unprognostic (5.83e-2)" "unprognostic (8.71e-2)" "prognostic unfavorable (1.24e-6)" "unprognostic (4.95e-2)" "unprognostic (7.23e-2)" "unprognostic (3.93e-2)" "unprognostic (4.48e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (3.97e-1)" "unprognostic (5.70e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" 17.4 12.9 17.4 13.3 19.7 23.4 12.8 18.4 21.6 13.9 16.1 25.6 9.5 13.2 9.6 9.9 16.9 8.6 20.4 17.0 18.2 6.2 9.0 12.8 8.0 19.3 18.2 14.6 7.3 4.5 8.1 7.1 19.2 11.4 7.0 16.3 11.6 9.7 10.5 8.5 12.5 12.4 18.7 15.7 18.4 24.7 17.6 10.3 10.6 7.4 6.6 19.5 12.6 25.3 49.0 16.3 46.3 45.2 29.0 17.9 10.1 22.5 19.3 24.7 30.4 7.0 19.4 43.9 10.3 26.3 31.1 12.0 37.8 19.1 18.9 49.6 35.9 58.7 39.6 20.0 27.5 34.0 35.9 29.8 9.2 21.1 21.2 34.7 29.3 31.5 30.8 181.4 32.2 20.9 48.4 38.0 20.5 21.7 31.3 38.9 16.5 31.6 15.1 7.8 37.5 79.1 31.8 31.9 14.9 11.8 13.5 20.0 29.1 17.6 23.9 41.4 52.8 101.5 39.1 41.8 56.8 81.6 51.2 0.4 1.3 0.0 0.6 0.7 0.2 0.1 0.3 0.4 1.0 0.2 0.0 0.2 0.5 0.0 0.4 0.0 0.4 0.2 17.4 19.7 18.4 21.6 17.0 18.2 19.3 18.2 19.2 18.7 17.6 25.3 42.1 0.0 2.3 11.1 7.2 51.7 6.6 3.9 16.5 26.2 25.5 29.3 28.9 4.3 3.7 7.3 22.9 2.1 22.5 4.8 0.0 2.2 23.1 23.6 34.3 27.3 19.7 20.2 12.5 3.5 9.3 19.9 19.4 7.4 7.0 13.5 14.6 9.0 9.3 25.2 14.6 10.5 0.0 77.2 13.8 6.2 10.2 77.0 33.8 3.7 15.2 57.7 2.1 7.1 15.4 2.4 2.7 6.4 17.6 8.6 6.4 6.2 9.9 46.3 52.6 12.5 31.7 63.7 15.2 16.1 53.0 1.2 27.0 12.3 11.1 4.1 SCLT1 "FLJ30655, hCAP-1A" ENSG00000151466 "Sodium channel and clathrin linker 1" Q96NL6 4 128864921-129093600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Astrocytes: 110.0;Excitatory neurons: 111.1;Inhibitory neurons: 116.0;Oligodendrocyte precursor cells: 109.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 66.0" "Group enriched" "Detected in all" 5 "granulocytes: 66.0;monocytes: 31.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036560, HPA036561" Approved Uncertain Microtubules,Cytosol NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Microtubules, Cytosol" "HPA036560: AB_2675190, HPA036561: AB_10673658" "unprognostic (2.15e-1)" "unprognostic (2.01e-1)" "unprognostic (1.62e-2)" "unprognostic (3.77e-2)" "unprognostic (5.05e-2)" "unprognostic (9.18e-2)" "unprognostic (1.33e-3)" "unprognostic (1.64e-2)" "unprognostic (1.94e-2)" "unprognostic (4.99e-2)" "unprognostic (3.86e-1)" "unprognostic (3.09e-2)" "unprognostic (5.34e-4)" "unprognostic (6.54e-2)" "unprognostic (2.70e-1)" "unprognostic (6.05e-2)" "unprognostic (8.92e-2)" 3.6 3.0 3.7 6.4 4.5 14.4 3.5 7.4 4.8 3.7 0.9 3.7 4.3 3.5 2.2 3.9 3.1 4.6 3.6 2.4 2.8 2.7 3.5 3.5 7.3 4.5 4.3 4.5 3.3 2.9 2.9 4.6 3.5 2.4 4.4 2.9 2.6 2.7 1.5 3.2 3.4 3.6 4.7 7.5 3.5 4.9 5.3 8.8 3.0 1.8 6.7 4.4 3.4 3.9 19.9 5.3 18.8 12.4 6.5 10.5 10.3 16.5 14.8 17.8 16.3 5.7 17.1 17.0 10.4 9.3 12.4 7.4 12.5 12.2 18.5 38.9 10.0 22.7 10.2 6.5 8.9 27.1 17.0 6.7 4.3 14.2 14.2 8.5 14.0 8.6 25.7 39.8 15.6 8.8 20.8 13.0 8.4 14.2 10.5 12.2 19.2 10.6 11.4 5.5 28.1 8.2 12.7 11.5 11.1 8.2 6.8 10.8 13.2 14.5 17.6 19.7 22.3 19.3 15.5 29.0 8.1 29.7 22.2 18.3 16.9 36.8 3.8 24.6 2.2 3.9 2.6 2.7 9.5 3.7 2.5 3.4 66.0 10.2 31.1 4.4 3.7 6.5 3.7 4.5 7.4 4.8 2.4 2.8 4.5 4.3 3.5 4.7 5.3 3.9 16.1 12.8 9.8 110.0 18.0 11.1 8.9 5.8 8.0 15.2 6.1 7.4 21.2 15.7 9.0 1.8 29.2 13.8 34.8 9.1 3.9 6.5 63.2 20.3 18.4 11.9 5.4 9.0 111.1 6.3 21.5 16.3 28.1 14.3 12.0 16.5 9.3 1.6 13.3 16.8 116.0 8.1 8.2 21.6 18.0 51.8 10.8 28.4 8.8 87.1 33.8 8.9 82.4 109.1 90.5 9.0 9.8 9.1 24.0 2.7 8.2 3.1 16.7 21.6 13.1 14.4 16.5 19.6 12.1 13.1 13.9 9.3 21.2 30.5 10.6 5.6 SCTR ENSG00000080293 "Secretin receptor" P47872 2 119439843-119525301 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 26.6;pancreas: 68.2" "Group enriched" "Detected in some" 6 "Alveolar cells type 2: 54.4;Ductal cells: 92.0;Exocrine glandular cells: 93.8;Pancreatic endocrine cells: 41.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 15.3" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 5 "basophil: 1.5" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.5" "Cell line enriched" "Detected in single" 5 "Karpas-707: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA007269 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 1: Pancreatic cells - Digestion" "HPA007269: AB_1856640" "unprognostic (1.51e-1)" "unprognostic (2.22e-1)" "unprognostic (4.99e-2)" "unprognostic (5.82e-2)" "unprognostic (1.71e-1)" "unprognostic (4.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-2)" "unprognostic (9.08e-2)" "unprognostic (7.35e-2)" "unprognostic (2.38e-2)" "unprognostic (6.11e-3)" "unprognostic (1.65e-3)" "unprognostic (1.77e-1)" "unprognostic (2.24e-1)" "unprognostic (4.38e-2)" 0.3 0.4 0.3 0.2 0.3 0.3 0.0 0.6 1.2 0.0 0.3 0.1 26.6 0.2 0.2 0.3 0.4 0.4 0.3 0.4 0.4 12.5 0.4 8.6 0.1 0.3 0.2 0.4 68.2 0.1 0.2 0.1 0.4 0.0 0.0 2.4 0.0 0.0 0.2 0.2 3.8 0.0 0.2 0.3 4.5 0.5 0.6 0.1 0.9 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.9 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.6 1.2 0.4 0.4 0.3 0.2 0.4 0.2 0.6 0.4 0.0 0.0 54.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 3.4 0.0 1.8 5.5 0.0 0.0 0.0 0.1 11.7 92.0 4.5 0.0 0.2 0.1 2.4 0.0 3.0 93.8 0.0 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.7 5.0 4.1 0.1 0.0 0.0 0.0 1.7 0.0 0.2 0.0 1.0 1.6 0.3 0.0 0.0 0.7 41.9 0.0 0.0 0.0 0.1 0.1 0.5 0.0 1.9 0.0 0.0 0.6 0.3 0.9 0.0 0.0 0.3 0.4 0.0 0.1 0.0 SELENOK SELK ENSG00000113811 "Selenoprotein K" Q9Y6D0 3 53884417-53891962 "Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 373.5;Proximal tubular cells: 415.0;Syncytiotrophoblasts: 350.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 471.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 471.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA008196 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "HPA008196: AB_1856665" "unprognostic (1.29e-2)" "unprognostic (1.18e-2)" "unprognostic (3.85e-1)" "prognostic favorable (7.18e-4)" "unprognostic (9.92e-2)" "unprognostic (1.53e-1)" "unprognostic (3.02e-2)" "prognostic favorable (3.76e-4)" "unprognostic (2.75e-1)" "unprognostic (5.21e-2)" "unprognostic (8.34e-2)" "unprognostic (1.14e-1)" "unprognostic (3.40e-2)" "unprognostic (8.43e-2)" "unprognostic (8.12e-2)" "unprognostic (9.35e-2)" "unprognostic (2.56e-3)" 39.6 51.9 52.3 27.0 53.0 70.1 35.8 55.2 67.9 29.8 52.3 35.9 23.3 29.1 64.4 27.8 33.9 23.4 90.1 52.0 55.8 42.1 74.2 38.3 23.7 55.0 53.7 48.6 51.7 55.7 62.8 26.5 55.5 34.6 29.3 86.5 29.7 28.5 86.7 24.1 30.4 18.7 55.7 32.3 39.6 32.0 53.3 26.7 43.0 61.2 29.4 35.5 26.1 58.4 22.4 14.9 34.3 23.3 52.1 32.8 36.8 32.0 40.5 43.4 48.9 33.4 33.1 33.8 13.8 23.4 48.7 13.8 40.7 24.5 37.8 59.6 50.3 21.1 61.4 77.6 49.1 28.3 48.6 19.8 40.3 30.1 39.4 25.2 35.3 25.1 20.1 86.3 38.5 24.7 18.5 33.5 33.4 27.5 55.1 11.5 20.9 61.9 51.3 37.1 17.5 49.5 21.9 29.4 32.7 37.5 19.6 44.0 20.6 24.4 28.7 62.2 45.7 62.8 76.3 31.4 36.8 37.3 38.2 471.4 41.7 110.7 69.5 47.2 67.5 60.3 63.0 70.0 36.6 49.0 55.0 63.0 94.1 52.2 56.6 66.3 72.1 82.6 52.3 53.0 55.2 67.9 52.0 55.8 55.0 53.7 55.5 55.7 53.3 58.4 223.1 134.6 103.9 0.0 173.5 0.0 0.0 0.0 0.0 0.0 233.7 237.5 0.0 0.0 53.9 149.0 0.0 162.3 373.5 0.0 189.8 258.5 0.0 150.1 113.5 62.7 0.0 0.0 0.0 199.6 239.6 86.9 0.0 237.9 237.1 59.1 0.0 0.0 162.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.6 0.0 0.0 74.9 0.0 0.0 0.0 0.0 282.5 0.0 0.0 110.6 0.0 0.0 415.0 53.9 0.0 0.0 0.0 86.0 0.0 0.0 0.0 0.0 350.1 155.9 94.7 0.0 0.0 SELENOS "AD-015, MGC2553, SBBI8, SELS, SEPS1, VIMP" ENSG00000131871 "Selenoprotein S" Q9BQE4 15 101270817-101277500 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 229.2;Glandular and luminal cells: 211.7;Pancreatic endocrine cells: 226.1;Syncytiotrophoblasts: 303.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 606.9" "Lineage enriched" "Detected in all" 5 "dendritic cells: 606.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010025 Approved Enhanced "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "HPA010025: AB_1079900" "unprognostic (1.90e-1)" "unprognostic (4.03e-2)" "unprognostic (1.06e-1)" "prognostic favorable (1.33e-4)" "unprognostic (2.42e-2)" "unprognostic (3.74e-3)" "unprognostic (3.18e-2)" "unprognostic (1.98e-1)" "unprognostic (9.83e-2)" "prognostic favorable (5.19e-4)" "unprognostic (2.42e-3)" "unprognostic (4.42e-1)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.67e-1)" "unprognostic (1.44e-1)" "unprognostic (2.66e-2)" 65.6 75.4 30.6 48.4 32.8 50.6 55.0 33.8 39.8 50.1 39.7 82.4 80.0 41.9 75.5 55.6 44.6 45.5 66.3 29.8 32.7 48.7 84.7 59.6 49.2 35.2 33.2 41.6 103.7 51.1 44.5 57.6 35.3 53.6 87.2 28.7 73.8 49.1 71.0 48.4 82.2 42.9 33.7 58.7 67.2 92.7 32.4 24.1 55.8 48.7 53.1 60.7 45.3 36.3 45.3 68.8 61.2 54.5 129.8 91.1 52.4 136.4 100.2 89.8 90.2 82.3 105.0 33.6 49.6 117.5 150.8 125.1 66.6 59.7 58.6 63.5 91.8 57.2 62.5 86.8 206.5 43.5 63.9 80.2 166.3 60.3 177.7 70.7 68.1 44.3 58.3 369.0 97.4 71.7 31.7 67.6 46.8 169.9 45.7 41.6 50.1 74.7 90.7 104.2 34.5 88.5 93.0 85.7 193.8 79.9 64.0 96.2 73.6 84.0 57.1 116.4 103.3 272.5 246.3 49.9 92.2 50.8 104.2 134.4 66.4 81.2 94.1 84.0 91.1 62.2 71.4 101.1 58.6 51.4 53.7 79.6 23.1 95.6 100.1 606.9 71.4 63.7 30.6 32.8 33.8 39.8 29.8 32.7 35.2 33.2 35.3 33.7 32.4 36.3 164.0 118.6 108.6 0.0 47.8 0.0 0.0 0.0 0.0 0.0 172.5 129.4 0.0 0.0 64.4 154.5 0.0 125.9 87.7 0.0 31.3 183.9 0.0 127.0 165.2 53.3 0.0 0.0 0.0 189.3 229.2 91.6 0.0 211.7 30.3 53.5 0.0 0.0 120.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.4 0.0 0.0 92.0 0.0 0.0 0.0 0.0 226.1 0.0 0.0 101.0 0.0 0.0 73.0 56.9 0.0 0.0 0.0 78.5 0.0 0.0 0.0 0.0 303.7 40.4 100.9 0.0 0.0 SELENOT SELT ENSG00000198843 "Selenoprotein T" P62341 3 150602875-150630445 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 215.1;Extravillous trophoblasts: 230.6;Hofbauer cells: 238.8;Pancreatic endocrine cells: 206.0;Proximal tubular cells: 176.8;Syncytiotrophoblasts: 489.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039780 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA039780: AB_10805594" "unprognostic (1.13e-1)" "unprognostic (4.03e-2)" "unprognostic (2.78e-1)" "unprognostic (1.92e-1)" "unprognostic (3.31e-1)" "unprognostic (1.34e-2)" "unprognostic (2.65e-3)" "unprognostic (1.49e-1)" "unprognostic (8.96e-2)" "unprognostic (5.79e-3)" "unprognostic (6.30e-3)" "unprognostic (1.99e-1)" "unprognostic (3.08e-3)" "unprognostic (4.91e-2)" "unprognostic (4.08e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-2)" 49.2 73.5 44.0 56.4 47.2 100.0 47.8 49.8 58.9 44.0 44.8 49.1 51.2 39.2 62.7 41.0 49.1 38.9 51.9 46.0 52.2 75.4 72.4 51.0 80.5 46.9 46.9 36.0 45.4 84.2 45.6 60.6 49.9 49.5 56.6 69.7 45.5 48.8 44.9 28.3 50.3 54.1 50.5 46.4 45.1 39.7 47.7 58.3 67.2 54.0 73.2 63.4 32.0 53.9 232.1 94.9 57.1 51.8 86.7 84.0 111.3 174.3 127.3 120.7 79.6 145.9 129.1 125.6 192.2 128.7 107.5 76.1 89.6 110.3 177.7 124.8 77.3 130.9 48.4 68.1 94.6 77.1 102.5 74.1 86.5 107.6 92.1 86.7 132.2 58.2 31.0 359.9 173.4 137.6 107.5 46.1 65.4 134.2 99.0 79.0 73.8 215.4 102.6 132.7 64.2 39.8 106.4 64.4 74.8 71.2 133.6 96.2 125.7 65.1 41.1 121.1 172.6 261.3 151.4 176.1 88.8 142.1 56.9 218.1 163.8 142.5 133.7 138.4 148.5 119.6 111.3 125.4 126.5 102.3 87.4 110.1 198.8 106.3 155.7 90.7 132.3 324.7 44.0 47.2 49.8 58.9 46.0 52.2 46.9 46.9 49.9 50.5 47.7 53.9 80.6 60.9 67.9 0.0 53.4 0.0 0.0 0.0 0.0 0.0 97.2 66.5 0.0 0.0 29.1 108.5 0.0 215.1 114.7 0.0 97.8 166.8 0.0 63.9 46.8 35.5 0.0 0.0 0.0 135.0 230.6 30.9 0.0 64.7 45.4 31.5 0.0 0.0 238.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.5 0.0 0.0 123.5 0.0 0.0 0.0 0.0 206.0 0.0 0.0 21.0 0.0 0.0 176.8 32.8 0.0 0.0 0.0 37.1 0.0 0.0 0.0 0.0 489.3 48.1 63.4 0.0 0.0 SEMA4A "CORD10, FLJ12287, SEMAB, SemB" ENSG00000196189 "Semaphorin 4A" Q9H3S1 1 156147366-156177752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Angiogenesis, Differentiation, Immunity, Neurogenesis" "Developmental protein" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 51.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 63.7;Plasma cells: 61.2;Skeletal myocytes: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 123.9;eosinophil: 120.2;intermediate monocyte: 132.7;myeloid DC: 183.0;neutrophil: 210.7;non-classical monocyte: 76.1" "Group enriched" "Detected in all" 13 "dendritic cells: 183.0;granulocytes: 210.7;monocytes: 132.7" "Cell line enhanced" "Detected in many" "Karpas-707: 151.8;U-698: 67.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069136 Supported NA NA 3300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA069136: AB_2686093" "unprognostic (1.90e-1)" "unprognostic (2.39e-2)" "unprognostic (4.24e-1)" "unprognostic (5.20e-2)" "unprognostic (8.04e-2)" "prognostic favorable (1.09e-4)" "unprognostic (1.97e-1)" "unprognostic (2.50e-2)" "unprognostic (3.51e-1)" "unprognostic (1.60e-2)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (8.20e-4)" "unprognostic (8.77e-2)" "unprognostic (4.63e-2)" "unprognostic (6.06e-2)" "unprognostic (1.28e-2)" 6.1 1.0 22.7 24.8 21.5 37.5 9.1 6.1 23.2 10.8 4.7 6.9 3.6 3.0 51.3 32.5 7.9 8.8 3.0 25.3 23.0 18.1 2.1 15.2 31.5 12.2 15.5 5.2 4.0 1.5 3.6 1.8 15.3 16.3 6.1 2.0 19.2 12.5 3.1 32.3 4.8 3.6 11.4 26.9 10.6 4.1 29.0 8.1 23.1 2.2 33.1 10.8 17.4 13.1 12.6 0.0 0.5 0.0 0.0 0.9 0.3 0.2 0.4 0.1 0.2 0.1 0.3 8.1 0.3 0.6 0.1 11.7 0.9 10.0 0.4 3.5 0.0 0.4 0.2 0.4 0.4 18.5 1.1 0.6 9.2 0.2 0.4 2.3 0.9 2.8 1.3 151.8 0.5 15.2 0.1 6.5 3.6 12.4 0.0 0.6 0.3 5.4 17.9 24.1 0.1 0.3 0.0 19.2 1.0 1.7 22.3 23.3 0.9 0.0 0.1 0.0 0.0 29.3 3.0 67.6 0.5 17.5 0.4 16.0 123.9 120.2 4.0 132.7 8.5 13.2 1.3 8.0 183.0 10.9 0.2 1.3 210.7 4.3 76.1 25.7 1.4 66.4 22.7 21.5 6.1 23.2 25.3 23.0 12.2 15.5 15.3 11.4 29.0 13.1 13.6 19.2 63.7 25.8 13.9 23.5 22.5 25.8 24.5 1.9 28.3 27.6 5.9 14.3 13.8 40.5 0.0 0.9 9.8 6.5 1.9 6.1 6.4 12.9 21.6 9.5 3.6 1.3 7.5 0.7 0.4 20.9 22.4 33.5 17.7 0.6 9.3 0.6 15.4 0.0 5.2 24.1 8.2 22.8 42.1 4.3 1.8 37.8 16.0 1.0 32.6 6.3 2.1 1.0 1.0 1.1 7.2 1.2 61.2 14.2 0.8 0.7 9.6 0.4 0.0 100.1 11.3 3.1 0.7 39.0 27.6 1.8 10.0 1.4 17.6 15.6 SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 349.0;Inhibitory neurons: 548.3;Oligodendrocyte precursor cells: 170.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 5 "B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0" "Cell line enhanced" "Detected in many" "AF22: 16.1;Karpas-707: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 66000 "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA049022: AB_2680602, HPA057259: AB_2683384" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (4.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (2.01e-2)" "unprognostic (2.71e-3)" "unprognostic (6.52e-2)" "prognostic favorable (6.34e-8)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (6.06e-2)" "unprognostic (7.81e-5)" 7.3 1.9 2.0 3.7 3.7 1.8 6.3 11.6 5.7 11.6 0.0 10.9 1.7 8.3 7.2 4.5 7.2 5.0 4.3 2.6 0.2 7.4 4.7 6.6 5.3 0.0 0.1 7.7 5.8 3.7 2.7 7.2 0.1 7.8 3.5 3.0 4.3 9.2 10.7 4.4 4.6 7.4 0.0 3.7 5.6 1.8 0.0 4.4 5.1 9.7 4.7 8.1 8.5 3.8 0.0 2.4 16.1 0.0 4.1 1.2 1.0 1.3 3.0 1.5 1.3 0.2 0.0 1.0 0.5 1.8 1.0 4.8 1.8 4.9 1.0 1.4 0.8 0.0 1.8 1.2 0.0 0.0 0.0 3.8 2.0 0.0 3.0 2.7 0.5 0.0 0.1 44.7 0.4 0.8 0.0 0.1 2.0 0.0 1.1 5.6 0.0 5.5 4.9 3.9 8.2 4.2 0.0 0.0 0.9 7.1 2.2 0.0 0.0 9.5 3.3 0.0 7.7 8.6 0.5 0.0 5.8 0.2 5.5 0.1 0.0 0.0 0.4 0.6 0.0 2.0 0.0 0.2 0.0 3.0 0.0 0.1 0.0 0.0 1.0 2.8 0.0 0.1 2.0 3.7 11.6 5.7 2.6 0.2 0.0 0.1 0.1 0.0 0.0 3.8 7.6 0.0 1.8 85.5 42.4 15.4 8.6 8.3 7.4 12.5 11.0 12.6 3.9 14.3 4.2 16.5 18.8 1.5 25.5 1.6 3.9 4.5 1.3 12.9 15.6 8.3 12.0 0.8 349.0 3.5 1.4 29.3 4.1 14.8 0.0 0.7 17.9 16.5 2.0 3.3 548.3 4.4 10.2 2.4 8.7 3.7 62.7 4.6 3.6 88.1 1.5 10.7 6.2 170.4 62.9 3.7 9.1 39.9 29.6 8.1 0.4 10.5 5.8 18.2 6.6 18.4 28.6 0.3 0.8 4.0 15.2 0.8 5.9 0.1 4.7 1.5 SF3B2 "Cus1, SAP145, SF3b1, SF3b145" ENSG00000087365 "Splicing factor 3b subunit 2" Q13435 11 66050729-66069308 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045028 Supported Enhanced "Nuclear speckles" NA NA 130000 "Cluster 5: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA045028: AB_10965174" "unprognostic (1.48e-1)" "unprognostic (1.51e-1)" "unprognostic (6.45e-2)" "unprognostic (3.29e-1)" "unprognostic (9.86e-2)" "unprognostic (7.10e-2)" "prognostic unfavorable (6.43e-5)" "unprognostic (8.43e-2)" "unprognostic (4.69e-1)" "unprognostic (2.79e-1)" "unprognostic (3.15e-2)" "unprognostic (1.44e-1)" "prognostic favorable (3.51e-5)" "unprognostic (4.03e-2)" "unprognostic (3.56e-1)" "unprognostic (5.14e-2)" "unprognostic (2.60e-2)" 116.0 96.0 117.5 80.4 127.1 144.6 109.0 119.4 139.5 123.3 125.1 97.4 70.7 111.6 95.5 96.6 112.3 55.2 94.7 117.9 120.4 107.1 112.0 104.3 99.0 124.2 118.9 136.1 137.4 88.9 137.2 80.6 121.3 99.2 77.0 96.5 91.3 73.8 108.1 116.9 98.5 80.0 121.4 113.9 102.9 145.2 124.0 109.4 115.2 54.6 114.0 108.3 104.7 136.9 226.9 177.3 189.0 178.9 184.3 163.5 153.1 168.4 210.5 234.9 176.8 149.8 188.9 212.5 185.7 186.7 249.5 202.9 263.2 177.8 208.8 170.2 143.5 223.3 164.2 245.5 187.8 229.7 171.5 137.9 174.0 242.5 287.8 171.3 172.7 180.5 215.2 348.7 191.4 309.8 257.5 343.2 196.1 166.2 163.9 235.6 162.9 299.0 192.3 186.0 147.8 218.0 165.9 175.9 257.0 136.3 217.2 147.1 156.7 206.9 178.0 229.0 194.3 267.5 337.0 270.8 229.6 151.6 191.9 152.1 96.2 167.9 135.3 117.2 131.1 106.8 120.3 128.2 98.5 110.2 116.7 116.8 130.2 116.3 160.1 78.8 131.8 147.5 117.5 127.1 119.4 139.5 117.9 120.4 124.2 118.9 121.3 121.4 124.0 136.9 86.5 128.2 131.0 18.6 144.3 111.3 148.9 165.9 129.1 94.9 69.1 65.0 68.5 98.7 141.5 66.2 89.6 195.9 131.8 114.3 92.0 172.2 278.2 119.5 103.2 104.4 82.5 113.6 19.2 214.8 183.7 117.6 95.8 92.0 120.8 119.0 80.7 72.4 124.9 107.7 19.3 112.4 130.2 103.6 115.0 78.5 120.2 103.8 65.8 10.3 195.6 122.1 155.5 12.1 28.9 158.9 96.3 130.1 198.3 136.6 101.1 108.1 214.7 109.4 78.9 106.1 153.7 220.1 172.0 103.2 99.0 186.6 145.5 118.7 122.3 130.8 SGCE DYT11 ENSG00000127990 "Sarcoglycan epsilon" O43556 7 94524204-94656572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 116.6;Oligodendrocyte precursor cells: 133.2;Oligodendrocytes: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 2.1;memory B-cell: 4.4;naive B-cell: 6.6" "Group enriched" "Detected in many" 4 "B-cells: 6.6;T-cells: 2.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074790 Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane" Yes No 170000 "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA074790: AB_2686713" "unprognostic (3.16e-3)" "unprognostic (9.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.19e-2)" "unprognostic (2.82e-2)" "unprognostic (6.93e-2)" "unprognostic (3.37e-1)" "unprognostic (6.80e-3)" "unprognostic (9.69e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" 43.2 63.4 19.9 9.4 21.6 0.4 36.5 22.1 31.6 45.1 20.9 51.6 8.0 43.2 27.1 13.3 40.7 27.6 38.9 19.6 21.0 19.5 14.4 30.5 16.7 23.2 20.6 92.2 21.5 10.9 30.9 52.7 22.4 18.0 12.8 16.8 21.1 31.6 8.5 8.2 19.2 41.8 21.9 25.1 23.8 18.5 20.4 12.8 23.9 19.8 7.2 35.6 34.6 26.7 13.5 42.5 39.6 61.8 63.7 110.8 7.1 51.3 92.3 40.7 60.4 24.9 78.0 12.8 70.4 86.5 83.7 9.4 60.0 21.6 49.1 2.2 32.7 1.4 36.9 28.3 44.0 4.3 0.0 95.5 31.1 64.8 79.3 104.9 30.8 0.0 0.1 93.7 43.5 42.6 0.0 0.0 32.8 8.0 29.0 19.8 51.0 25.8 78.6 13.6 26.2 20.8 0.0 52.2 65.1 44.2 17.6 0.8 0.0 131.1 45.1 11.8 81.7 50.8 67.9 14.8 51.4 0.2 74.2 0.7 0.0 0.1 2.1 0.0 0.8 4.4 0.6 1.0 0.0 6.6 0.2 0.7 0.3 1.0 0.1 0.2 0.2 0.3 19.9 21.6 22.1 31.6 19.6 21.0 23.2 20.6 22.4 21.9 20.4 26.7 39.2 70.5 33.3 66.9 6.1 5.0 18.4 16.8 1.8 18.6 9.7 44.4 18.6 30.0 28.3 20.2 4.2 90.2 1.4 0.0 5.9 42.5 1.6 4.0 17.1 18.8 1.2 0.4 85.2 4.3 26.1 116.6 1.5 6.6 2.5 37.3 58.2 11.2 6.3 20.2 68.5 0.1 12.2 2.5 7.3 3.7 75.5 1.4 51.6 15.9 0.0 31.5 0.0 133.2 116.3 2.1 0.0 58.3 2.6 5.5 0.0 14.1 13.7 30.3 85.5 68.0 60.7 17.1 13.0 0.9 4.0 82.8 2.7 44.0 0.0 2.2 SH2D1B EAT2 ENSG00000198574 "SH2 domain containing 1B" O14796 1 162395268-162412138 "Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.5;skeletal muscle: 12.1;tongue: 6.6" "Group enriched" "Detected in some" 7 "dendritic cells: 47.3;NK-cells: 154.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 8 "NK-cell: 376.5;non-classical monocyte: 149.2" "Group enriched" "Detected in many" 38 "monocytes: 149.2;NK-cells: 376.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.4;EFO-21: 2.7;Karpas-707: 4.4;TIME: 1.3" "Not detected" "Not detected" HPA054791 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054791: AB_2682600" "unprognostic (7.82e-3)" "unprognostic (6.06e-3)" "unprognostic (1.41e-1)" "unprognostic (2.52e-2)" "unprognostic (1.43e-3)" "unprognostic (2.55e-3)" "unprognostic (1.89e-2)" "unprognostic (6.54e-2)" "unprognostic (5.96e-2)" "unprognostic (4.35e-1)" "unprognostic (1.12e-1)" "unprognostic (4.92e-2)" "unprognostic (1.42e-2)" "unprognostic (2.72e-1)" "unprognostic (3.80e-1)" "unprognostic (8.45e-2)" "unprognostic (1.15e-3)" 0.5 0.0 0.7 0.7 1.1 4.5 0.2 0.0 1.0 0.1 0.1 0.5 0.8 0.7 0.1 1.4 0.2 0.5 0.1 0.7 0.1 0.4 1.0 2.2 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.5 0.0 0.3 0.6 12.1 0.0 1.1 0.1 0.1 7.5 0.1 0.3 0.2 0.2 0.1 6.6 1.0 0.2 1.4 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 1.1 6.7 31.0 0.4 0.3 0.1 1.8 6.8 0.1 0.4 1.3 3.0 376.5 149.2 0.5 0.4 67.3 0.7 1.1 0.0 1.0 0.7 0.1 0.1 0.2 0.2 0.1 0.2 1.2 0.1 3.2 0.6 1.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 1.3 0.0 0.0 0.0 47.3 0.2 0.0 0.0 0.1 1.4 0.3 0.2 0.0 5.3 4.3 0.0 0.0 0.2 0.0 2.1 0.0 0.0 1.8 0.6 0.1 0.0 0.5 0.0 0.0 1.6 0.3 0.5 0.0 2.0 0.0 1.0 1.6 0.0 154.5 0.0 0.7 0.5 0.0 0.0 3.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.0 13.9 0.0 0.1 0.0 SH2D2A "F2771, TSAd" ENSG00000027869 "SH2 domain containing 2A" Q9NP31 1 156806243-156816848 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 33.9;dendritic cells: 139.5;NK-cells: 113.3;T-cells: 103.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 30 "NK-cells: 28.5;T-cells: 66.5" "Cell line enhanced" "Detected in many" "HDLM-2: 46.5;HMC-1: 33.3;Karpas-707: 81.0;RPMI-8226: 24.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.5;hippocampal formation: 1.6" HPA074482 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA074482: " "prognostic favorable (4.96e-4)" "unprognostic (2.76e-2)" "unprognostic (7.50e-2)" "unprognostic (3.03e-3)" "unprognostic (1.14e-3)" "unprognostic (2.73e-1)" "unprognostic (3.11e-1)" "unprognostic (9.80e-2)" "unprognostic (3.08e-1)" "unprognostic (1.64e-1)" "unprognostic (9.34e-3)" "unprognostic (1.70e-1)" "prognostic unfavorable (5.26e-12)" "unprognostic (1.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.79e-1)" "prognostic favorable (1.31e-4)" 3.5 0.9 1.0 11.4 1.1 4.3 1.3 3.8 1.6 1.8 1.9 2.2 2.5 1.7 0.3 1.2 1.5 3.3 2.5 0.9 1.5 2.5 2.2 5.4 9.4 1.9 1.1 0.6 1.0 0.3 1.8 0.8 1.5 2.5 2.0 3.4 0.9 0.7 0.4 0.4 5.4 1.6 1.2 13.0 2.9 0.3 1.1 14.9 1.6 0.0 5.9 3.7 1.2 1.3 2.6 0.4 0.0 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 1.7 2.4 0.0 6.8 0.0 0.0 0.0 0.4 1.3 0.1 46.5 0.1 6.8 0.5 0.9 0.2 0.4 33.3 0.5 0.0 0.2 3.3 0.0 0.3 11.8 1.9 81.0 0.0 0.2 5.9 0.7 4.9 4.1 8.3 0.9 0.0 24.5 0.1 0.3 7.5 0.0 1.6 0.9 0.8 0.5 0.2 1.3 2.2 0.0 0.0 0.3 0.5 11.6 16.6 8.3 0.0 6.9 0.2 1.0 0.1 0.0 66.5 0.0 61.8 1.1 27.6 40.8 0.1 0.3 10.4 27.2 1.5 28.5 0.2 0.1 34.1 18.6 1.0 1.1 3.8 1.6 0.9 1.5 1.9 1.1 1.5 1.2 1.1 1.3 1.2 3.2 2.3 0.0 4.6 2.2 0.3 0.4 1.2 33.9 1.0 1.9 0.9 0.0 1.3 0.0 0.0 0.1 139.5 1.2 0.0 0.3 0.2 0.2 2.5 0.6 1.2 6.1 0.0 0.6 1.0 4.8 9.2 0.5 8.2 0.3 1.8 0.9 1.1 0.0 0.0 0.9 0.0 1.9 2.1 0.0 0.0 4.1 0.0 1.9 1.1 1.3 113.3 0.0 0.5 6.1 1.4 0.0 24.2 0.5 0.3 0.2 0.7 1.6 0.0 0.5 2.9 0.1 4.9 3.0 1.3 0.1 103.2 0.1 1.8 0.5 SH3BGRL MGC117402 ENSG00000131171 "SH3 domain binding glutamate rich protein like" O75368 X 81202102-81298547 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051248 Approved Approved Vesicles NA NA 13000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA051248: AB_2681405" "unprognostic (3.02e-3)" "unprognostic (4.25e-2)" "unprognostic (4.89e-2)" "unprognostic (3.15e-2)" "unprognostic (1.46e-1)" "unprognostic (1.39e-1)" "unprognostic (2.25e-2)" "unprognostic (3.20e-2)" "unprognostic (1.23e-1)" "unprognostic (1.51e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.08e-4)" "unprognostic (2.12e-1)" "unprognostic (3.75e-1)" "unprognostic (1.73e-1)" 112.1 120.0 92.4 101.1 92.4 176.7 170.8 98.1 126.3 146.2 94.3 180.8 87.6 208.5 148.8 130.4 112.3 149.1 61.1 88.0 108.2 126.0 62.6 133.0 154.9 104.8 95.6 130.7 81.3 112.3 83.5 86.4 105.2 153.1 108.5 24.9 112.5 284.9 16.5 67.1 98.1 231.7 104.4 144.4 87.0 54.3 96.1 145.1 104.7 50.2 126.8 178.3 76.0 116.3 1.0 38.2 133.4 154.1 172.1 232.0 9.2 83.4 158.3 30.1 61.1 12.5 114.6 113.7 70.1 122.9 42.4 20.7 95.9 60.0 48.0 98.7 33.3 151.2 59.7 7.4 41.6 107.3 286.0 135.6 42.9 42.4 37.6 231.4 133.8 75.9 53.0 279.6 165.9 53.9 117.0 138.7 105.2 1.4 62.3 102.0 60.9 60.8 155.7 52.8 0.4 58.5 0.1 4.2 77.9 88.0 44.8 321.2 136.9 82.7 34.1 76.4 35.0 64.3 60.6 105.6 95.1 215.9 62.9 793.9 358.5 570.7 124.9 477.3 134.8 236.3 154.7 147.8 306.2 207.4 140.8 148.8 126.7 183.0 560.5 148.0 257.5 462.3 92.4 92.4 98.1 126.3 88.0 108.2 104.8 95.6 105.2 104.4 96.1 116.3 191.3 112.2 92.6 73.8 216.1 126.3 131.5 150.4 83.1 16.2 174.6 150.2 19.7 72.9 106.4 121.4 0.0 7.1 183.9 33.2 344.4 86.9 6.3 74.9 120.0 130.7 93.3 172.9 62.8 74.7 6.0 152.4 63.2 62.6 219.7 92.8 139.9 17.8 431.4 5.0 82.4 87.0 109.9 400.9 430.7 19.2 174.3 379.0 147.7 102.1 459.0 154.2 224.6 82.9 54.3 48.0 104.2 314.1 114.4 83.5 91.2 214.3 113.6 8.5 263.0 132.4 308.8 4.5 5.9 76.0 119.5 5.7 163.4 205.9 90.3 146.4 SHANK2 "CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3" ENSG00000162105 "SH3 and multiple ankyrin repeat domains 2" Q9UPX8 11 70467854-71252577 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.5;Horizontal cells: 136.3;Inhibitory neurons: 167.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 7.7;basal ganglia: 7.5;cerebral cortex: 9.3;hippocampal formation: 9.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 11.5;Karpas-707: 17.5;RT4: 15.9;T-47d: 16.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008174, HPA017220" Approved Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Nuclear speckles" "HPA008174: AB_1856822, HPA017220: " "unprognostic (3.08e-1)" "unprognostic (1.31e-3)" "unprognostic (1.79e-1)" "unprognostic (1.51e-2)" "unprognostic (1.51e-1)" "unprognostic (7.23e-5)" "unprognostic (1.24e-1)" "unprognostic (6.67e-2)" "unprognostic (1.83e-2)" "unprognostic (8.42e-2)" "unprognostic (4.87e-2)" "unprognostic (4.01e-1)" "prognostic favorable (1.94e-6)" "unprognostic (3.46e-2)" "unprognostic (2.34e-1)" "unprognostic (4.03e-2)" "unprognostic (4.80e-2)" 1.3 1.2 7.7 0.5 7.5 0.0 4.5 0.2 9.3 1.3 31.7 2.4 1.5 1.0 2.2 3.4 5.1 0.8 0.0 9.5 0.0 4.9 3.8 3.7 0.1 0.0 0.0 0.1 7.5 0.1 2.2 1.9 0.0 3.2 2.0 5.5 9.8 1.8 0.0 0.9 1.3 0.4 0.0 1.1 3.0 0.9 1.0 0.0 6.0 0.0 0.4 1.1 0.3 0.9 0.5 7.4 4.1 0.0 0.6 0.4 4.5 0.7 0.3 0.0 0.0 6.6 3.1 6.2 2.2 0.0 0.1 1.1 0.0 4.8 0.0 0.0 0.2 0.0 0.0 11.5 0.0 0.0 1.9 0.1 1.8 0.0 0.0 1.6 0.0 0.1 0.0 17.5 1.7 10.5 0.0 0.1 3.5 10.2 0.3 0.0 9.9 8.2 5.2 15.9 3.5 1.1 0.0 8.4 0.0 5.2 16.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 7.5 0.2 9.3 9.5 0.0 0.0 0.0 0.0 0.0 1.0 0.9 8.0 41.7 17.0 21.5 0.2 0.0 3.2 3.2 0.6 17.9 26.9 13.0 3.7 11.5 5.4 7.3 0.0 12.8 0.4 3.2 3.9 8.4 1.7 30.0 3.2 1.3 0.0 0.0 153.5 2.2 2.9 1.8 10.2 13.0 2.5 1.2 0.4 21.9 1.2 136.3 167.5 7.9 8.2 0.0 0.3 2.1 0.0 0.4 5.4 14.0 0.0 4.6 0.0 41.7 5.3 10.7 2.7 0.7 0.4 10.9 0.6 10.8 23.3 1.0 0.0 0.3 1.3 0.7 0.9 1.3 0.6 14.6 0.3 0.1 5.5 4.0 SHLD3 "AC008560.1, CTC-534A2.2, FLJ26957, RINN1" ENSG00000253251 "Shieldin complex subunit 3" Q6ZNX1 5 65625027-65630928 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 17.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 4.0;dendritic cells: 5.9;Distal tubular cells: 3.9;Pancreatic endocrine cells: 4.6;Proximal tubular cells: 5.3;Syncytiotrophoblasts: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066071, HPA068764" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 34: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Nucleoli "HPA066071: AB_2685609, HPA068764: AB_2686028" "unprognostic (7.87e-2)" "unprognostic (1.56e-1)" "unprognostic (1.34e-1)" "unprognostic (1.82e-1)" "unprognostic (1.29e-1)" "unprognostic (9.52e-2)" "unprognostic (5.58e-4)" "unprognostic (2.20e-2)" "unprognostic (1.38e-2)" "unprognostic (7.24e-3)" "unprognostic (5.09e-4)" "unprognostic (2.12e-2)" "unprognostic (1.68e-2)" "unprognostic (1.49e-1)" "unprognostic (1.37e-1)" "unprognostic (1.94e-1)" "prognostic favorable (1.17e-4)" 2.3 2.7 2.4 2.7 2.5 17.5 4.2 2.8 3.6 1.8 1.8 2.8 2.8 2.3 3.1 1.5 1.9 2.4 1.8 2.3 2.1 2.9 2.6 2.5 4.8 2.4 2.1 1.5 3.4 2.1 2.5 2.5 2.3 4.3 3.0 3.7 2.0 2.5 1.8 2.9 2.7 1.7 2.4 2.5 2.4 3.2 2.4 3.9 2.4 1.9 3.6 2.5 1.3 3.2 2.6 3.6 5.0 10.8 2.9 3.5 6.3 3.8 3.5 5.8 7.0 5.9 8.0 4.9 4.2 4.6 6.5 3.1 5.1 4.7 8.5 6.7 6.5 4.3 10.3 8.3 2.5 5.0 7.5 2.1 6.8 6.0 6.1 1.6 3.7 7.7 6.4 11.5 4.7 6.9 6.7 7.7 4.0 1.5 2.2 4.4 4.9 7.9 4.9 6.0 6.7 5.5 3.2 3.3 11.0 3.4 3.8 4.6 3.0 5.0 6.8 4.1 6.6 7.2 14.3 10.7 3.7 6.1 4.7 15.9 3.0 6.4 3.8 2.9 4.0 3.9 4.5 4.0 2.8 3.1 6.1 5.6 3.3 4.9 3.1 3.2 6.2 2.1 2.4 2.5 2.8 3.6 2.3 2.1 2.4 2.1 2.3 2.4 2.4 3.2 3.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.8 3.6 0.0 0.0 0.0 0.0 0.0 4.0 5.9 0.0 3.9 3.1 0.0 1.9 1.8 0.8 0.0 0.0 0.0 2.9 3.8 0.9 0.0 2.1 0.0 2.1 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 0.0 0.0 5.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.1 1.8 2.1 0.0 0.0 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SKA1 "C18orf24, MGC10200" ENSG00000154839 "Spindle and kinetochore associated complex subunit 1" Q96BD8 18 50375040-50394168 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.0;lymphoid tissue: 4.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.3;Extravillous trophoblasts: 9.2;Plasma cells: 10.0;Spermatocytes: 16.7;Spermatogonia: 13.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "Karpas-707: 82.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA045495 Approved Approved Microtubules NA Yes "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "HPA045495: AB_10960405" "unprognostic (2.18e-2)" "unprognostic (7.85e-3)" "unprognostic (7.66e-3)" "unprognostic (5.93e-3)" "unprognostic (1.91e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (9.60e-8)" "unprognostic (1.03e-3)" "unprognostic (1.16e-2)" "unprognostic (1.20e-2)" "unprognostic (1.18e-4)" "unprognostic (3.91e-3)" "unprognostic (0.00e+0)" "unprognostic (4.50e-3)" "unprognostic (4.66e-2)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" 0.4 0.5 0.9 2.2 0.8 12.0 0.3 2.5 1.1 0.4 0.8 1.6 1.7 0.6 0.2 2.5 0.2 0.3 0.2 1.0 0.5 0.1 0.3 0.4 4.9 1.0 0.9 0.2 0.4 0.1 0.0 1.6 1.2 0.3 2.1 0.4 0.3 0.1 0.6 1.5 1.4 1.1 0.3 1.3 0.8 4.3 1.3 3.6 0.3 0.2 4.8 0.5 0.7 2.4 27.1 10.8 18.6 19.0 1.2 2.1 9.9 30.7 10.6 29.9 28.5 4.7 10.6 21.1 7.6 11.0 25.8 23.6 25.6 13.0 31.4 34.6 2.6 27.0 5.5 18.3 2.3 42.2 26.8 1.5 1.3 20.7 8.2 3.2 20.0 20.0 30.8 82.6 26.4 5.7 34.6 12.1 14.2 6.5 6.4 17.3 18.3 23.5 8.5 1.6 13.7 10.9 17.2 9.9 13.6 15.3 11.4 20.2 10.1 32.8 19.0 12.8 31.8 27.5 41.6 32.4 18.2 34.9 33.3 0.9 0.4 0.1 0.1 0.1 0.1 0.2 0.1 0.5 0.2 0.3 0.2 0.1 0.6 0.6 0.2 0.2 0.4 0.2 0.9 0.8 2.5 1.1 1.0 0.5 1.0 0.9 1.2 0.3 1.3 2.4 0.2 0.0 2.2 0.0 2.8 1.0 0.2 0.4 0.0 0.4 0.7 0.6 0.4 0.0 0.8 0.0 2.1 4.4 0.7 1.6 0.0 0.1 4.5 0.5 0.7 0.4 1.2 22.3 0.2 0.0 9.2 1.4 0.5 1.1 0.0 4.9 2.2 0.1 5.3 0.0 0.1 2.7 0.0 0.8 0.9 2.2 0.3 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 1.1 0.0 10.0 0.4 0.1 0.1 0.2 0.8 0.0 0.2 1.4 16.7 13.5 3.7 0.3 1.5 1.4 0.5 3.4 1.0 SLA "hSLAP, SLA1, SLAP, SLAP-1" ENSG00000155926 "Src like adaptor" Q13239 8 133036728-133102912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 97.4;lymphoid tissue: 156.6" "Cell type enhanced" "Detected in many" "dendritic cells: 224.2;Hofbauer cells: 67.4;Kupffer cells: 199.4;Macrophages: 154.2;NK-cells: 109.2;Plasma cells: 83.0;T-cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HMC-1: 47.9;JURKAT: 201.5;Karpas-707: 129.2;MOLT-4: 35.8;U-266/84: 76.1;U-937: 55.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012296, HPA074192" Enhanced Approved "Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane, Cytosol" "HPA012296: AB_1856946, HPA074192: AB_2686673" "unprognostic (1.19e-2)" "unprognostic (6.29e-3)" "unprognostic (2.73e-3)" "unprognostic (6.07e-3)" "unprognostic (1.66e-2)" "unprognostic (1.10e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (9.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.66e-1)" "unprognostic (3.05e-2)" "unprognostic (8.60e-2)" "unprognostic (1.65e-1)" 25.2 13.1 9.5 82.9 6.4 97.4 9.5 6.1 11.5 11.1 8.2 10.8 7.9 5.2 2.9 9.4 7.0 20.9 5.2 8.2 9.1 6.4 16.9 25.9 78.6 12.0 8.4 3.0 5.8 3.1 3.1 15.2 10.3 5.2 8.4 1.3 4.6 3.6 1.5 4.0 20.7 12.5 9.7 70.3 12.5 1.4 16.9 156.6 27.6 4.4 71.0 22.0 4.2 14.6 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 0.1 2.3 0.0 0.0 0.0 6.3 47.9 0.8 0.0 0.6 0.0 0.2 0.0 201.5 0.1 129.2 0.0 0.0 35.8 9.3 0.0 0.0 0.0 0.2 0.3 7.8 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.1 0.0 15.3 0.0 0.1 0.3 0.2 0.1 6.9 76.1 0.0 0.6 55.6 0.0 0.7 110.2 203.6 87.6 123.1 110.1 41.0 79.7 88.2 79.8 48.3 75.3 77.4 262.3 132.6 148.4 6.3 124.4 158.9 9.5 6.4 6.1 11.5 8.2 9.1 12.0 8.4 10.3 9.7 16.9 14.6 2.4 9.6 19.1 0.7 36.6 2.2 0.3 0.0 0.0 9.7 0.9 1.3 3.3 1.5 10.5 0.0 0.0 0.4 224.2 0.2 0.0 0.2 0.2 0.7 0.7 5.9 0.0 13.2 1.0 0.0 1.2 4.5 3.6 0.5 37.2 1.7 8.9 2.9 67.4 0.0 1.3 0.5 0.0 199.4 15.0 1.0 0.3 154.2 5.4 14.0 36.7 0.1 109.2 0.0 0.1 0.0 0.0 0.0 83.0 0.1 0.0 0.3 5.1 0.3 6.6 1.4 1.9 0.0 0.1 0.3 2.7 0.1 160.0 0.1 0.1 0.2 SLC10A7 "C4orf13, DKFZp313H0531, DKFZp566M114, DKFZp779O2438, MGC25043" ENSG00000120519 "Solute carrier family 10 member 7" Q0GE19 4 146253975-146521964 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 44.4;Microglial cells: 50.6;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039996 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA039996: AB_10673266" "unprognostic (9.44e-2)" "unprognostic (4.03e-1)" "unprognostic (3.39e-3)" "unprognostic (5.07e-2)" "unprognostic (1.01e-1)" "unprognostic (9.02e-2)" "unprognostic (7.96e-2)" "unprognostic (2.54e-1)" "unprognostic (3.55e-1)" "unprognostic (8.53e-2)" "unprognostic (2.68e-3)" "unprognostic (1.24e-1)" "unprognostic (1.43e-2)" "unprognostic (8.99e-2)" "unprognostic (2.79e-1)" "unprognostic (6.69e-2)" "unprognostic (9.57e-2)" 5.4 4.6 2.6 4.9 4.0 6.0 6.0 3.2 2.6 7.2 1.7 7.0 4.6 4.9 12.0 5.8 4.4 5.6 2.9 2.9 3.6 3.8 7.2 5.9 5.6 4.6 3.8 5.6 6.5 3.7 3.6 8.9 4.9 6.3 9.2 3.9 6.9 3.3 2.2 3.7 5.4 5.9 3.8 5.3 9.7 3.4 3.5 6.5 7.0 3.2 5.9 4.7 4.8 5.1 5.2 1.7 12.2 5.0 8.6 10.3 5.8 6.3 8.2 5.7 5.8 4.7 21.6 9.6 4.4 6.9 3.6 5.2 7.2 8.6 6.8 11.1 3.5 11.8 4.2 8.5 5.5 20.5 18.3 4.9 6.8 6.9 8.7 3.1 10.2 10.2 13.2 25.6 4.3 3.6 15.6 5.2 2.2 11.4 8.6 8.6 8.9 13.7 4.0 3.8 3.7 3.1 4.3 12.8 5.3 6.4 7.5 8.1 5.8 5.1 5.4 7.8 4.4 20.7 24.9 13.4 7.0 8.2 7.4 10.9 3.0 4.5 3.7 4.8 3.8 3.9 3.7 3.3 4.0 2.8 3.5 3.4 0.3 5.1 3.9 2.7 4.9 2.2 2.6 4.0 3.2 2.6 2.9 3.6 4.6 3.8 4.9 3.8 3.5 5.1 10.8 3.2 3.9 44.4 7.9 3.3 4.2 2.0 2.8 6.8 5.2 3.7 2.1 8.6 3.2 1.8 4.2 6.4 8.2 6.2 1.9 4.0 2.3 4.8 6.2 5.4 4.8 9.9 34.3 5.1 13.2 6.1 11.2 6.0 22.9 5.8 8.9 10.3 5.8 8.4 37.1 14.7 2.0 7.3 3.1 1.2 7.5 6.1 0.0 50.6 4.9 3.4 6.2 62.4 82.0 3.6 3.4 4.9 15.8 3.3 4.2 1.9 7.3 11.8 0.0 4.0 5.5 7.0 4.5 5.2 4.8 6.2 8.6 2.3 7.6 4.1 SLC25A21 "ODC, ODC1" ENSG00000183032 "Solute carrier family 25 member 21" Q9BQT8 14 36677921-37172606 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 6.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 27.8;Excitatory neurons: 14.1;Exocrine glandular cells: 10.0;Inhibitory neurons: 10.4;Oligodendrocyte precursor cells: 11.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "K-562: 26.4;Karpas-707: 54.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000662 Uncertain NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA000662: AB_1080000" "unprognostic (6.81e-3)" "unprognostic (6.98e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-1)" "unprognostic (2.78e-2)" "unprognostic (2.20e-1)" "unprognostic (2.44e-2)" "unprognostic (1.09e-1)" "unprognostic (7.32e-2)" "unprognostic (6.86e-2)" "unprognostic (9.16e-2)" "unprognostic (1.66e-1)" "unprognostic (6.70e-4)" "unprognostic (9.09e-3)" "unprognostic (1.95e-2)" "unprognostic (3.52e-1)" "unprognostic (1.07e-1)" 0.9 1.2 0.2 0.3 0.3 6.3 0.5 0.3 0.3 0.6 0.1 0.6 0.7 1.3 0.2 1.2 0.7 0.6 1.3 0.2 0.4 1.6 0.4 0.5 0.1 0.4 0.3 2.0 2.8 0.9 0.3 0.1 0.4 1.6 0.3 1.0 1.6 0.4 0.7 0.3 1.2 0.7 0.4 0.5 0.8 3.9 0.3 0.3 1.5 0.9 0.1 0.6 0.3 0.5 1.3 1.0 0.4 3.2 0.1 1.0 0.0 0.3 0.8 1.7 0.7 0.2 0.9 0.1 1.4 0.4 0.0 1.0 0.0 0.7 0.6 0.8 9.5 0.9 0.8 0.8 1.0 0.0 0.0 0.7 1.1 0.0 0.5 0.9 3.9 0.0 26.4 54.4 0.8 2.7 0.0 0.0 2.1 0.0 4.1 0.0 0.0 0.0 0.8 3.9 2.6 0.0 2.6 0.2 1.3 0.4 2.9 0.0 1.9 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.2 0.4 0.4 0.3 0.4 0.4 0.3 0.5 0.3 0.0 0.0 2.3 0.2 1.0 1.8 1.8 6.8 0.1 1.0 0.9 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.1 1.9 0.9 1.4 0.1 1.0 0.7 1.8 27.8 14.1 10.0 0.0 0.9 0.0 0.2 0.0 0.4 0.7 0.3 0.2 1.7 10.4 0.5 2.0 0.0 0.4 1.4 1.5 0.1 0.0 4.7 0.0 4.3 0.0 11.6 5.2 3.7 0.0 0.7 0.0 2.7 0.1 4.2 0.4 1.5 0.0 1.1 1.1 3.1 3.6 3.6 0.9 0.0 0.1 1.9 1.0 0.6 SLC25A45 ENSG00000162241 "Solute carrier family 25 member 45" Q8N413 11 65375192-65383701 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 34.2" "Cell type enhanced" "Detected in many" "dendritic cells: 46.7;NK-cells: 103.0;Proximal enterocytes: 90.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 17.5;Karpas-707: 22.8;RPMI-8226: 17.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA042495, HPA050821" Uncertain Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA042495: , HPA050821: AB_2681249" "unprognostic (3.73e-2)" "unprognostic (2.19e-3)" "unprognostic (8.44e-4)" "unprognostic (6.17e-3)" "unprognostic (2.57e-2)" "unprognostic (2.84e-7)" "unprognostic (7.57e-3)" "unprognostic (4.59e-2)" "unprognostic (1.44e-1)" "unprognostic (4.06e-2)" "prognostic favorable (2.83e-4)" "unprognostic (1.96e-1)" "unprognostic (1.08e-2)" "unprognostic (1.45e-1)" "unprognostic (1.54e-1)" "unprognostic (6.18e-2)" "unprognostic (1.43e-1)" 3.7 3.3 3.1 5.8 3.3 4.9 4.7 2.8 4.1 1.9 2.6 3.4 5.6 1.8 2.5 2.5 2.0 2.0 3.8 3.1 3.1 6.5 12.1 3.9 10.1 3.7 3.1 1.9 34.2 3.0 6.6 1.9 3.5 3.8 1.8 0.3 6.3 1.9 7.1 2.9 7.6 1.3 3.3 13.3 2.8 1.9 3.1 8.0 12.1 3.7 6.6 2.0 1.9 4.0 0.4 5.8 0.2 8.5 1.5 0.7 4.2 1.0 2.6 0.5 0.5 1.4 2.7 5.2 4.7 2.4 2.1 0.8 0.6 0.4 0.0 17.5 1.2 5.7 3.2 0.4 0.9 1.8 5.7 1.9 0.1 0.7 0.5 0.4 0.9 9.9 0.8 22.8 0.9 1.9 4.2 0.1 0.3 0.3 2.6 7.7 1.1 17.1 0.9 0.1 2.8 3.7 1.8 4.5 1.0 0.5 2.4 0.9 1.7 0.6 2.0 5.5 0.4 9.5 6.4 1.5 1.7 1.3 3.3 10.5 6.3 4.8 8.8 11.2 9.3 10.6 7.8 8.5 6.9 11.9 12.4 9.3 3.9 17.1 13.3 23.0 7.7 3.1 3.1 3.3 2.8 4.1 3.1 3.1 3.7 3.1 3.5 3.3 3.1 4.0 5.0 0.0 5.6 0.3 40.0 2.8 5.9 4.2 3.4 12.3 10.7 7.7 5.6 8.6 4.7 12.9 0.0 2.1 46.7 14.4 0.0 5.9 5.1 6.2 3.1 6.0 6.7 3.0 5.2 5.4 1.7 7.7 5.6 7.9 4.5 21.8 6.8 14.0 7.3 6.7 0.6 16.7 4.1 9.7 14.4 3.9 6.8 11.7 5.4 4.7 18.4 5.5 103.0 1.5 3.9 5.2 12.5 3.8 15.3 7.0 90.9 6.9 12.3 0.4 6.6 12.6 3.6 2.2 0.4 2.2 2.0 1.5 31.6 11.8 13.3 4.6 SLC25A53 MCART6 ENSG00000269743 "Solute carrier family 25 member 53" Q5H9E4 X 104099214-104157009 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Daudi: 6.1;Karpas-707: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA034959 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA034959: AB_10602025" "unprognostic (4.70e-2)" "unprognostic (1.16e-2)" "unprognostic (7.16e-3)" "unprognostic (5.94e-2)" "unprognostic (2.68e-2)" "unprognostic (5.23e-2)" "unprognostic (1.98e-1)" "unprognostic (5.49e-3)" "unprognostic (4.45e-3)" "unprognostic (7.94e-2)" "unprognostic (9.76e-5)" "unprognostic (1.83e-1)" "unprognostic (2.04e-1)" "unprognostic (3.48e-2)" "unprognostic (1.74e-1)" "unprognostic (3.53e-1)" "unprognostic (1.76e-2)" 0.1 0.3 1.0 1.0 1.0 0.4 0.2 1.3 1.1 0.2 0.3 0.2 0.4 0.2 0.2 0.1 0.2 0.3 0.3 1.1 0.9 0.1 0.1 0.2 1.9 0.9 1.1 0.4 0.5 0.1 0.2 0.1 0.9 0.2 0.4 0.4 0.1 0.1 0.1 0.2 1.0 0.2 1.0 1.3 0.4 0.6 1.0 0.5 0.1 0.0 1.6 0.2 0.1 1.3 0.0 0.1 1.7 1.1 0.1 0.0 0.1 0.2 0.1 0.2 0.2 0.1 0.0 6.1 0.1 0.0 0.3 0.1 2.0 0.0 0.1 0.5 0.8 0.7 0.2 0.1 0.1 1.1 0.7 0.3 0.0 0.2 0.0 0.3 0.4 0.6 0.1 13.9 0.1 0.1 0.2 0.1 2.2 0.1 0.4 2.5 0.9 0.2 0.3 0.2 1.5 2.1 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.1 0.8 0.1 0.4 0.1 0.0 2.2 0.1 1.6 0.4 0.2 0.1 0.2 0.3 0.1 0.6 0.5 0.3 0.5 0.1 0.4 0.0 0.3 0.7 0.2 0.0 0.0 0.5 0.1 1.0 1.0 1.3 1.1 1.1 0.9 0.9 1.1 0.9 1.0 1.0 1.3 6.6 6.4 4.6 26.4 11.4 5.2 8.8 6.2 4.0 3.5 7.2 5.7 15.1 5.7 4.6 9.2 0.0 3.7 9.6 17.3 25.4 4.3 6.8 6.9 4.7 5.3 7.2 19.4 15.5 6.0 4.2 7.6 7.7 7.2 7.0 2.7 6.4 25.1 10.6 3.3 14.1 7.8 4.1 8.8 5.7 1.3 3.1 7.5 1.8 16.9 11.4 4.0 17.5 17.1 23.5 7.8 21.8 3.0 10.2 8.8 19.7 25.9 10.8 8.1 0.0 5.2 5.0 4.8 2.3 4.7 5.7 6.2 11.0 3.0 4.5 11.3 SLC35F6 "ANT2BP, C2orf18, FLJ20555, TANGO9" ENSG00000213699 "Solute carrier family 35 member F6" Q8N357 2 26764284-26781231 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 129.9;Karpas-707: 117.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034655 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Cytosol" "HPA034655: AB_10696359" "unprognostic (2.26e-1)" "unprognostic (7.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.54e-1)" "unprognostic (7.71e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.11e-4)" "prognostic unfavorable (3.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.35e-1)" "unprognostic (3.24e-1)" "unprognostic (2.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.07e-2)" "unprognostic (9.95e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-2)" 18.6 20.7 9.6 7.3 10.5 4.6 16.2 10.1 9.2 14.5 8.4 10.1 7.9 11.9 7.3 22.0 10.7 7.3 13.8 9.6 11.8 19.5 17.7 11.9 6.5 13.9 12.9 8.5 10.3 21.3 10.8 9.4 12.3 11.4 5.7 5.8 14.5 8.1 12.8 21.2 10.0 10.1 10.4 10.8 11.3 5.1 13.0 5.7 16.0 9.9 7.6 12.1 13.0 11.6 24.6 43.6 12.3 32.6 41.7 19.4 20.4 14.9 20.3 16.8 15.2 27.9 44.5 6.6 23.4 18.7 42.0 29.4 18.1 26.9 11.8 11.5 10.1 7.6 16.4 23.3 129.9 7.8 36.4 29.8 26.9 18.9 62.7 7.6 19.9 9.6 14.2 117.3 16.9 40.5 10.0 7.0 7.6 17.2 10.9 8.9 35.9 10.9 44.1 20.3 9.6 12.7 22.8 37.4 25.4 10.1 14.1 8.2 19.2 21.8 24.0 30.7 15.2 23.9 32.6 12.9 23.6 13.4 21.0 12.1 18.1 8.0 11.9 25.6 7.0 4.8 8.2 10.8 11.4 3.6 5.3 7.9 11.7 13.6 30.9 7.8 5.9 9.5 9.6 10.5 10.1 9.2 9.6 11.8 13.9 12.9 12.3 10.4 13.0 11.6 39.0 12.8 10.5 11.8 5.9 17.0 13.2 10.2 7.4 17.2 17.5 10.2 13.5 28.6 11.1 33.1 6.2 24.1 12.0 21.5 7.9 34.2 1.7 13.4 29.7 20.8 9.1 0.8 6.9 38.7 22.3 25.2 12.2 22.8 1.3 11.9 31.8 25.4 51.2 15.2 7.9 11.2 8.2 61.0 16.8 1.5 18.3 28.8 28.4 4.7 19.8 19.2 11.3 9.0 10.8 48.2 14.3 12.0 5.5 18.3 21.5 57.2 9.0 11.1 26.3 17.8 20.2 3.7 7.1 14.9 25.7 38.0 10.6 16.8 11.2 11.7 SLC39A8 BIGM103 ENSG00000138821 "Solute carrier family 39 member 8" Q9C0K1 4 102251041-102431258 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 171.1" "Group enriched" "Detected in many" 5 "Alveolar cells type 1: 778.8;Alveolar cells type 2: 305.6;Extravillous trophoblasts: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 158.9;HL-60: 120.9;Karpas-707: 171.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038832, HPA038833" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA038832: AB_2676226, HPA038833: AB_10670910" "prognostic favorable (6.69e-4)" "unprognostic (1.29e-2)" "prognostic favorable (1.34e-4)" "unprognostic (1.91e-2)" "unprognostic (6.50e-2)" "unprognostic (9.59e-2)" "unprognostic (6.07e-2)" "unprognostic (2.74e-1)" "unprognostic (1.20e-3)" "unprognostic (6.32e-2)" "unprognostic (5.46e-3)" "unprognostic (2.78e-2)" "prognostic favorable (6.34e-6)" "unprognostic (3.25e-1)" "unprognostic (6.54e-2)" "unprognostic (6.40e-2)" "unprognostic (7.13e-3)" 45.5 3.5 9.6 28.9 10.7 36.5 18.1 10.2 12.1 84.7 9.9 37.8 6.7 11.0 5.7 3.0 11.9 7.8 30.4 8.3 10.5 18.3 40.0 171.1 13.3 14.6 10.7 14.0 54.5 42.0 8.0 13.0 14.4 8.4 43.0 6.4 89.3 6.6 1.1 9.4 7.3 9.1 14.2 6.7 7.8 2.6 13.5 14.4 12.3 2.0 12.3 20.8 6.8 11.6 20.2 19.5 4.4 0.1 15.8 35.4 10.1 2.2 158.9 5.8 9.3 0.9 72.5 19.3 21.0 0.6 20.0 1.4 13.5 4.4 3.4 34.1 39.5 51.0 37.5 0.3 6.3 120.9 16.8 19.1 5.0 3.1 9.1 15.4 2.1 47.1 51.6 171.2 30.7 13.4 43.7 55.9 13.0 26.8 19.0 11.0 0.2 63.8 33.3 7.4 5.6 14.0 55.0 1.0 5.3 3.8 13.4 44.4 11.3 19.3 7.3 39.1 31.6 76.3 34.1 90.4 31.0 77.4 18.2 0.0 1.8 1.4 6.3 1.1 10.9 1.8 11.7 10.0 3.3 3.9 8.6 5.9 0.1 13.7 0.4 1.2 5.0 4.2 9.6 10.7 10.2 12.1 8.3 10.5 14.6 10.7 14.4 14.2 13.5 11.6 16.1 778.8 305.6 15.7 14.5 11.7 9.2 35.9 5.2 2.6 42.8 13.1 21.3 4.3 23.9 5.5 4.2 19.2 14.9 20.3 11.7 1.8 0.7 17.7 5.2 19.8 24.0 46.7 6.6 32.7 217.5 17.4 4.1 40.9 3.8 32.4 5.7 26.1 42.9 3.3 1.5 74.1 6.1 29.8 79.0 0.7 1.2 28.9 28.4 60.9 10.8 5.2 9.2 5.0 1.7 11.8 26.2 1.2 56.0 9.6 2.1 17.7 2.9 1.6 6.6 2.6 8.8 2.3 6.0 2.1 7.0 60.6 23.6 31.0 64.3 6.8 SLC4A10 "NBCn2, NCBE" ENSG00000144290 "Solute carrier family 4 member 10" Q6U841 2 161424332-161985282 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.3;choroid plexus: 121.4;retina: 34.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 604.4;Inhibitory neurons: 560.9" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Region enhanced" "Detected in many" "cerebral cortex: 21.3" "Immune cell enriched" "Detected in some" 8 "MAIT T-cell: 63.3" "Lineage enriched" "Detected in single" 65 "T-cells: 63.3" "Cell line enriched" "Detected in single" 11 "Karpas-707: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034755, HPA076725" Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA034755: AB_10670296, HPA076725: " "unprognostic (4.64e-4)" "unprognostic (3.88e-1)" "unprognostic (2.88e-2)" "unprognostic (3.65e-2)" "unprognostic (1.19e-2)" "unprognostic (7.89e-3)" "unprognostic (5.99e-4)" "unprognostic (1.12e-1)" "unprognostic (2.27e-1)" "unprognostic (1.64e-1)" "unprognostic (2.50e-2)" "unprognostic (9.27e-2)" "unprognostic (5.65e-2)" "unprognostic (9.23e-3)" "unprognostic (1.87e-1)" "unprognostic (2.10e-3)" "unprognostic (2.26e-1)" 0.0 2.0 6.3 0.7 10.3 0.2 0.2 0.2 21.3 0.1 121.4 1.8 0.3 0.0 1.3 0.0 0.6 0.4 0.0 11.8 1.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.5 0.0 1.3 0.0 0.0 0.2 1.3 34.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.5 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 2.5 0.0 63.3 0.0 1.2 7.8 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.5 6.3 10.3 0.2 21.3 11.8 1.1 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 21.2 0.1 0.0 0.0 0.0 0.0 116.3 0.0 0.0 0.6 0.0 0.0 0.0 8.4 0.0 2.6 1.1 0.0 0.0 18.3 0.0 0.0 0.3 0.0 0.0 604.4 0.0 0.0 0.0 0.5 0.0 2.5 0.0 1.8 0.6 0.0 0.0 560.9 2.8 0.0 0.6 0.0 10.5 0.0 0.1 0.0 16.9 0.5 2.8 1.0 129.2 16.5 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 9.4 0.0 0.3 0.0 SLC9A9 "FLJ35613, NHE9" ENSG00000181804 "Solute carrier family 9 member A9" Q8IVB4 3 143265222-143848485 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 149.8;Inhibitory neurons: 159.5;Microglial cells: 396.3;Oligodendrocyte precursor cells: 272.9;Oligodendrocytes: 431.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 19.3;ASC TERT1: 24.9;HSkMC: 17.6;Karpas-707: 62.8;RPMI-8226: 30.4;U-266/70: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058234 Approved NA NA 280000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA058234: AB_2683648" "unprognostic (8.22e-2)" "unprognostic (6.88e-2)" "unprognostic (7.23e-3)" "unprognostic (1.65e-1)" "unprognostic (3.65e-2)" "unprognostic (7.05e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.18e-4)" "unprognostic (2.66e-1)" "unprognostic (1.35e-3)" "unprognostic (7.73e-2)" "unprognostic (4.51e-2)" "prognostic unfavorable (5.57e-7)" "unprognostic (5.01e-2)" "unprognostic (4.69e-2)" "unprognostic (1.56e-1)" "unprognostic (4.28e-2)" 12.8 5.1 9.7 8.8 14.4 2.0 5.3 12.5 11.3 6.9 6.9 7.3 3.0 4.2 3.7 12.8 6.8 9.6 5.4 9.9 16.3 2.3 7.1 5.9 14.7 20.4 13.5 7.9 1.0 3.0 3.4 15.9 19.5 8.8 5.8 1.3 4.5 8.5 2.1 7.7 7.0 8.0 14.4 13.1 5.0 1.8 13.8 15.5 3.5 5.0 13.5 11.4 7.7 18.2 0.5 0.5 0.8 1.0 19.3 24.9 0.3 1.0 6.6 0.5 3.1 0.0 0.2 3.0 0.2 2.9 1.5 0.7 0.9 1.9 0.8 12.8 0.2 1.6 0.4 0.0 2.2 0.8 1.3 17.6 5.2 0.7 0.9 1.1 0.3 2.3 0.0 62.8 4.2 0.0 1.5 0.0 0.2 0.0 0.5 2.6 0.1 30.4 0.0 0.5 0.4 0.0 1.5 0.0 0.0 0.4 0.2 0.6 0.0 2.4 0.6 2.8 1.4 29.1 0.1 0.1 4.3 0.4 1.2 0.2 6.2 0.7 4.7 10.6 4.0 3.3 4.9 7.5 8.4 3.7 2.7 4.0 0.5 4.2 9.0 0.6 9.3 4.8 9.7 14.4 12.5 11.3 9.9 16.3 20.4 13.5 19.5 14.4 13.8 18.2 4.5 0.0 1.1 149.8 13.2 3.7 10.4 8.7 22.8 0.2 0.6 1.3 1.5 0.0 3.4 3.7 2.1 0.5 10.4 0.0 0.0 1.0 4.8 0.8 10.1 4.4 0.0 9.9 25.6 0.2 0.5 26.5 7.1 0.8 0.0 0.7 21.8 0.0 55.4 0.0 159.5 0.0 6.1 30.5 9.9 4.4 9.3 31.0 7.2 396.3 24.3 2.8 13.4 272.9 431.8 0.8 0.1 7.2 10.9 11.1 0.0 0.4 1.6 0.1 0.0 18.0 7.0 0.3 0.4 23.9 5.1 1.1 19.7 3.7 0.1 3.9 SLFN12L ENSG00000205045 "Schlafen family member 12 like" Q6IEE8 17 35464249-35487857 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.1" "Group enriched" "Detected in some" 8 "dendritic cells: 16.0;NK-cells: 42.2;T-cells: 31.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 3.6" "Group enriched" "Detected in many" 6 "granulocytes: 1.0;NK-cells: 3.6;T-cells: 1.9" "Cell line enhanced" "Detected in some" "HDLM-2: 9.7;Karpas-707: 5.5" HPA024447 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA024447: AB_1856614" "unprognostic (1.93e-3)" "unprognostic (2.10e-4)" "unprognostic (3.77e-2)" "unprognostic (2.67e-2)" "unprognostic (8.18e-3)" "unprognostic (2.98e-5)" "unprognostic (4.59e-3)" "unprognostic (2.75e-2)" "unprognostic (6.82e-2)" "unprognostic (1.67e-2)" "unprognostic (9.51e-2)" "unprognostic (1.78e-1)" "unprognostic (2.25e-6)" "unprognostic (2.30e-1)" "unprognostic (3.88e-2)" "unprognostic (7.02e-2)" "unprognostic (8.88e-3)" 0.6 0.3 0.9 2.4 0.9 3.0 0.6 2.5 1.8 0.5 0.9 0.6 1.7 0.5 0.3 0.3 0.3 1.0 0.2 0.7 0.4 0.3 0.6 1.3 3.0 0.3 0.0 0.4 0.3 0.1 0.0 0.2 0.3 0.3 0.8 0.8 0.9 0.2 0.5 0.6 1.5 0.4 0.0 3.1 1.2 0.3 0.5 1.0 0.4 0.3 2.2 0.7 0.1 1.5 0.5 0.1 0.2 0.2 0.1 0.0 0.2 0.1 0.0 0.6 1.4 0.1 0.3 0.5 0.1 0.0 0.1 0.3 0.0 0.0 0.7 9.7 0.1 1.3 0.8 0.1 0.0 0.3 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.3 5.5 0.1 0.0 0.4 0.2 0.2 0.0 0.1 0.1 0.2 0.2 0.3 0.2 0.2 0.1 0.4 0.1 0.1 0.1 0.0 2.0 0.6 0.3 1.2 0.5 0.2 2.0 2.0 0.1 0.2 0.3 0.5 1.0 0.3 1.0 1.9 0.0 0.8 0.3 0.8 1.4 0.2 0.3 1.0 1.0 0.9 3.6 0.1 0.2 0.5 0.4 0.9 0.9 2.5 1.8 0.7 0.4 0.3 0.0 0.3 0.0 0.5 1.5 3.5 3.2 2.7 0.0 1.5 0.3 0.6 0.4 0.0 0.0 0.3 0.3 1.3 1.5 0.7 0.0 0.0 0.0 16.0 0.0 0.0 0.2 0.8 0.5 0.2 1.4 0.0 0.4 0.0 0.0 0.0 0.5 1.5 0.3 1.3 0.1 0.4 0.3 0.1 0.0 0.0 0.0 0.0 1.5 0.4 0.1 0.0 1.1 0.0 1.0 0.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 2.8 0.2 0.0 0.0 0.2 0.0 0.0 0.5 0.7 0.4 0.0 0.3 0.1 0.0 31.7 0.1 0.1 0.2 SMCO4 "C11orf75, FN5" ENSG00000166002 "Single-pass membrane protein with coiled-coil domains 4" Q9NRQ5 11 93478472-93543391 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 195.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 211.3;Paneth cells: 165.3;Proximal enterocytes: 200.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 113.7" "Low region specificity" "Detected in all" HPA041120 Uncertain NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "HPA041120: AB_2677309" "unprognostic (7.45e-2)" "unprognostic (1.70e-3)" "unprognostic (2.54e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-1)" "unprognostic (6.47e-2)" "unprognostic (8.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.43e-1)" "unprognostic (5.51e-1)" "unprognostic (4.23e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (5.81e-7)" "unprognostic (1.61e-1)" "unprognostic (3.05e-1)" "unprognostic (1.55e-2)" "unprognostic (5.01e-2)" 21.0 70.4 8.9 30.6 8.2 7.3 23.0 8.2 12.6 17.0 17.3 35.3 45.9 18.9 13.9 23.1 27.9 16.8 53.5 10.2 22.9 66.3 135.1 35.8 31.4 11.9 14.7 25.3 60.0 5.8 48.0 11.4 11.2 55.2 25.7 3.4 195.8 11.5 17.0 24.3 37.6 15.2 11.1 61.8 50.1 43.4 32.4 17.5 71.7 5.9 22.9 12.4 22.8 12.8 8.3 15.3 23.9 5.5 8.0 10.6 15.4 25.2 7.5 10.8 19.9 26.6 33.0 24.6 29.0 22.1 16.8 5.0 24.1 3.5 7.3 68.6 22.2 5.9 32.4 58.0 7.4 24.4 26.1 15.0 13.2 5.0 3.8 13.6 16.7 81.5 13.8 113.7 3.3 13.9 24.4 50.2 25.0 62.6 23.9 42.8 12.0 11.2 21.5 19.8 4.2 18.5 19.6 26.3 2.1 30.2 10.4 33.7 10.9 9.7 40.6 33.4 20.8 4.6 0.7 19.7 7.6 40.9 4.9 40.2 263.5 6.9 4.1 316.4 18.4 25.0 26.9 8.0 150.3 26.9 3.7 3.2 61.4 32.0 296.3 155.5 11.7 91.5 8.9 8.2 8.2 12.6 10.2 22.9 11.9 14.7 11.2 11.1 32.4 12.8 26.0 25.6 18.4 0.3 11.5 32.8 33.4 17.4 6.2 2.1 62.0 50.5 36.7 70.1 17.2 49.7 0.0 6.6 27.7 105.1 211.3 43.2 123.5 14.3 2.9 24.9 44.9 6.1 4.8 70.2 9.0 19.0 27.5 16.1 2.5 21.3 15.7 103.9 140.4 3.3 10.6 116.4 6.1 91.3 80.3 146.8 12.8 87.7 30.2 13.1 123.3 6.4 11.3 0.5 4.4 31.1 165.3 10.5 15.0 92.8 200.0 64.8 9.6 1.3 6.6 4.2 14.1 11.2 46.6 16.6 21.3 4.8 15.0 6.4 58.7 47.3 SMIM19 C8orf40 ENSG00000176209 "Small integral membrane protein 19" Q96E16 8 42541155-42555195 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011145, HPA074830" Uncertain Approved "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA011145: AB_1078360, HPA074830: " "unprognostic (2.12e-2)" "unprognostic (2.33e-3)" "unprognostic (4.01e-2)" "unprognostic (1.85e-2)" "unprognostic (1.42e-1)" "unprognostic (6.68e-3)" "unprognostic (7.04e-3)" "unprognostic (1.76e-2)" "unprognostic (4.84e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.67e-2)" "prognostic favorable (1.74e-6)" "unprognostic (5.10e-2)" "unprognostic (9.70e-3)" "unprognostic (9.64e-2)" "unprognostic (2.93e-3)" 55.2 57.1 34.7 18.4 35.4 32.5 64.9 35.8 44.3 31.9 35.8 41.7 30.0 32.6 80.0 33.2 57.0 27.8 59.6 36.1 35.8 76.9 136.8 31.5 36.9 34.2 34.9 42.2 68.5 36.2 26.8 23.3 35.1 31.9 34.6 21.1 62.6 30.1 121.8 44.8 38.9 25.1 35.7 33.3 46.2 43.9 35.0 36.6 73.5 74.1 33.9 36.4 29.9 37.3 38.9 28.5 61.0 52.6 35.9 43.2 19.9 29.9 40.2 23.4 27.8 6.8 84.4 42.4 12.2 25.1 57.0 27.2 31.8 19.2 24.3 33.8 26.3 35.9 17.9 15.5 73.9 25.7 9.0 35.4 16.1 19.6 62.7 45.3 21.5 49.1 28.8 94.5 23.7 38.0 18.8 39.0 72.1 90.4 19.5 21.1 43.4 72.4 60.7 28.5 12.7 46.0 30.0 32.2 93.1 32.6 68.0 48.2 27.3 14.7 12.5 40.8 19.6 88.7 53.8 56.9 62.2 40.9 39.6 92.2 42.3 31.4 46.3 34.0 56.5 71.3 59.6 57.0 65.1 68.3 55.6 54.3 15.3 80.7 28.8 107.2 78.2 40.0 34.7 35.4 35.8 44.3 36.1 35.8 34.2 34.9 35.1 35.7 35.0 37.3 53.1 22.4 45.9 5.9 43.0 45.8 63.5 89.8 70.6 25.2 89.9 108.8 75.7 88.6 66.2 33.1 6.2 90.1 58.6 36.2 201.5 67.9 183.9 109.6 26.0 43.9 16.3 45.6 12.7 126.8 62.9 65.5 43.3 54.8 40.0 52.3 47.8 142.5 78.3 23.5 13.4 74.4 61.1 45.9 51.0 77.5 69.0 47.3 92.5 11.2 64.0 66.7 42.2 10.6 14.6 85.5 69.5 59.5 29.0 53.3 161.9 228.2 110.9 14.3 26.3 67.6 50.7 131.3 48.6 58.4 49.6 47.2 43.3 76.4 74.8 63.2 SMIM35 TMPRSS4-AS1 ENSG00000255274 "Small integral membrane protein 35" A0A1B0GVV1 11 118003634-118088299 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.2;kidney: 1.1" "Cell type enhanced" "Detected in single" "Collecting duct cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Karpas-707: 10.9;RPMI-8226: 7.2" "Group enriched" "Detected in some" 5 "basal ganglia: 1.2;olfactory bulb: 3.5" "Region enriched" "Detected in some" 6 "basal ganglia: 7.9" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (8.83e-2)" "unprognostic (3.42e-2)" "unprognostic (2.64e-1)" "unprognostic (1.58e-1)" "unprognostic (3.04e-4)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.64e-1)" "unprognostic (1.88e-1)" 0.1 0.1 0.2 0.5 0.3 1.2 0.2 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.2 1.1 0.1 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.1 0.0 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 7.2 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.2 0.3 0.2 0.1 0.0 0.1 0.0 0.4 0.2 0.2 1.6 0.1 0.2 0.3 0.1 0.5 0.2 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMOX "C20orf16, dJ779E11.1, FLJ20746, MGC1010, PAO, PAOh1, SMO" ENSG00000088826 "Spermine oxidase" Q9NWM0 20 4120980-4187747 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 61.3" "Cell type enhanced" "Detected in many" "Ductal cells: 48.4;Erythroid cells: 89.7;Macrophages: 73.3;Pancreatic endocrine cells: 131.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.0;myeloid DC: 2.4;neutrophil: 3.6;plasmacytoid DC: 1.1" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.6;monocytes: 1.0" "Cell line enhanced" "Detected in many" "A549: 119.6;Karpas-707: 201.7;RPTEC TERT1: 91.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047117, HPA060198" Approved Supported "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Nuclear membrane, Vesicles, Cytosol" "HPA047117: AB_2679940, HPA060198: AB_2684220" "unprognostic (1.24e-2)" "unprognostic (6.55e-2)" "unprognostic (7.24e-3)" "unprognostic (2.77e-1)" "unprognostic (1.40e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (3.33e-6)" "prognostic unfavorable (1.36e-4)" "unprognostic (4.92e-2)" "unprognostic (3.37e-1)" "unprognostic (7.18e-2)" "unprognostic (7.58e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (4.08e-2)" "unprognostic (2.64e-3)" "unprognostic (1.26e-2)" "unprognostic (3.07e-1)" 8.5 4.4 50.9 4.4 61.3 32.2 5.3 54.5 60.9 17.7 32.8 5.6 10.6 10.8 7.1 8.5 7.4 15.1 6.8 46.3 51.7 20.5 8.5 4.9 4.8 56.6 54.4 12.5 32.5 25.2 13.2 6.2 53.7 12.2 1.2 2.9 12.1 7.9 4.3 11.9 8.1 4.0 53.0 6.4 20.1 5.8 55.5 4.3 6.8 2.8 2.6 8.2 12.4 54.1 11.0 119.6 8.3 6.3 5.5 8.2 14.6 15.6 29.8 11.1 7.4 49.5 29.6 0.0 5.1 14.4 18.0 21.6 6.8 7.5 4.8 0.0 3.5 21.5 4.1 50.6 35.0 4.1 8.3 31.3 13.1 23.1 9.8 13.4 19.8 16.7 4.8 201.7 6.7 3.3 8.1 12.1 10.2 10.7 16.3 7.3 10.3 29.1 91.4 8.3 1.6 7.2 28.9 3.4 54.1 4.2 0.3 5.1 24.0 12.7 12.0 2.3 12.2 9.1 1.7 0.1 10.6 5.4 9.8 0.0 1.0 0.2 0.0 0.4 0.0 0.1 0.2 0.2 2.4 0.0 0.0 0.0 3.6 0.3 0.1 1.1 0.0 16.0 50.9 61.3 54.5 60.9 46.3 51.7 56.6 54.4 53.7 53.0 55.5 54.1 4.4 0.0 0.5 38.5 3.8 12.6 12.0 14.4 6.8 0.5 6.9 4.6 1.7 12.8 6.3 11.0 0.0 0.4 0.2 1.4 0.0 48.4 4.0 9.2 15.8 11.2 6.0 89.7 1.6 30.5 0.8 11.3 6.6 18.7 5.7 10.4 13.6 2.3 20.6 0.0 3.5 3.0 6.1 3.1 10.2 7.7 14.6 73.3 8.8 5.6 22.6 25.4 1.0 9.0 6.2 131.3 1.5 13.5 7.4 13.1 4.0 3.8 1.2 1.4 0.0 2.7 10.2 19.1 7.8 2.1 10.5 0.3 2.1 1.9 3.7 12.6 SNX16 ENSG00000104497 "Sorting nexin 16" P57768 8 81799581-81842866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 82.8;Late spermatids: 137.3;Spermatocytes: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024730, HPA024731, HPA024817" Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA024730: AB_10600220, HPA024731: AB_1857346, HPA024817: AB_10602313" "unprognostic (5.50e-2)" "unprognostic (3.20e-2)" "unprognostic (1.40e-1)" "unprognostic (8.41e-3)" "unprognostic (3.21e-3)" "unprognostic (7.54e-3)" "unprognostic (1.24e-3)" "unprognostic (1.33e-1)" "unprognostic (2.12e-1)" "unprognostic (2.18e-1)" "unprognostic (3.94e-2)" "unprognostic (1.43e-1)" "unprognostic (5.73e-3)" "unprognostic (7.60e-3)" "unprognostic (2.30e-1)" "unprognostic (1.35e-1)" "unprognostic (3.65e-1)" 10.1 5.2 4.7 6.0 5.7 10.7 8.2 6.6 7.6 8.6 2.5 6.3 6.4 9.7 8.3 17.3 6.2 10.8 8.1 5.3 6.6 6.6 5.5 6.7 5.1 6.1 7.4 9.6 3.1 8.9 3.7 5.5 8.6 7.3 6.6 4.9 5.7 7.7 4.6 11.2 5.7 11.9 5.8 12.0 9.0 14.9 5.7 9.4 8.7 9.4 6.7 7.0 7.7 6.7 13.8 3.8 6.6 6.3 22.9 13.7 7.3 16.6 20.2 14.1 20.6 3.4 11.1 2.2 10.0 11.4 16.5 11.0 5.1 6.8 19.5 19.9 3.1 7.1 5.2 6.2 17.4 2.9 11.5 10.5 10.6 5.4 12.5 15.8 10.0 7.8 4.5 26.0 32.9 7.2 15.6 5.1 2.8 12.6 6.2 6.6 9.5 2.4 12.7 6.7 10.9 8.3 3.1 3.9 8.3 9.8 10.3 5.5 7.7 19.5 15.6 13.5 7.2 15.1 12.5 5.7 8.4 9.1 15.7 9.2 4.5 6.1 2.1 2.8 2.0 1.6 2.5 1.7 4.0 4.4 2.9 2.8 6.2 2.6 2.4 3.0 5.0 1.9 4.7 5.7 6.6 7.6 5.3 6.6 6.1 7.4 8.6 5.8 5.7 6.7 10.6 6.4 9.4 9.8 6.4 25.2 12.1 5.0 9.6 5.5 12.1 7.6 8.8 7.2 9.3 5.5 4.2 2.3 3.7 7.5 5.9 5.9 82.8 9.4 7.8 11.5 3.0 8.2 24.7 6.0 4.0 8.5 10.7 16.2 8.2 5.0 13.9 3.5 5.7 55.5 18.4 6.2 8.2 7.0 10.0 137.3 23.3 7.2 3.6 8.4 2.3 4.3 1.0 23.1 22.2 6.7 5.5 16.1 8.6 12.6 3.7 7.3 10.9 5.2 19.7 12.1 9.3 74.2 26.5 13.0 32.0 9.9 5.4 4.2 4.7 20.7 SNX27 "KIAA0488, MGC20471, MY014" ENSG00000143376 "Sorting nexin 27" Q96L92 1 151612006-151699091 "Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 21.4;classical monocyte: 35.8;intermediate monocyte: 30.8;myeloid DC: 16.3;neutrophil: 40.4;non-classical monocyte: 35.4" "Group enriched" "Detected in all" 5 "dendritic cells: 16.3;granulocytes: 40.4;monocytes: 35.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028551 Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA028551: " "unprognostic (3.35e-1)" "unprognostic (4.76e-1)" "unprognostic (1.38e-1)" "unprognostic (2.13e-2)" "unprognostic (2.79e-2)" "unprognostic (3.42e-1)" "unprognostic (2.41e-2)" "unprognostic (1.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (5.92e-2)" "unprognostic (1.63e-1)" "unprognostic (5.45e-2)" "unprognostic (2.81e-1)" "unprognostic (4.15e-1)" "unprognostic (7.30e-2)" "unprognostic (1.04e-1)" 7.6 8.6 18.1 7.7 24.7 8.7 7.2 20.2 21.1 9.1 9.2 14.4 5.3 9.1 9.2 7.5 8.6 6.7 8.8 17.1 23.2 14.5 8.5 8.9 6.8 21.5 21.5 9.7 6.9 11.8 10.2 10.7 21.8 9.5 7.4 15.9 7.2 11.6 17.6 9.6 8.3 10.0 20.5 11.2 8.5 7.9 20.1 7.2 7.4 21.3 6.5 12.4 8.2 22.3 9.7 14.2 14.7 18.6 22.9 16.8 32.7 5.1 10.5 8.9 9.5 11.6 12.5 9.1 10.9 8.3 9.5 11.7 19.1 10.4 11.0 13.1 6.9 14.7 8.4 13.1 15.1 17.8 9.6 13.4 7.7 10.2 11.6 9.0 10.1 14.3 9.0 54.8 11.8 17.3 10.6 12.2 26.1 19.0 9.0 10.8 14.3 11.8 13.9 14.3 14.7 12.6 13.8 25.4 10.1 15.8 16.3 14.9 13.4 12.5 8.2 13.1 10.9 11.4 12.2 17.8 14.8 11.2 14.2 21.4 35.8 5.4 4.6 30.8 6.6 3.2 5.8 4.2 16.3 4.4 5.5 4.6 40.4 3.5 35.4 4.2 5.1 17.3 18.1 24.7 20.2 21.1 17.1 23.2 21.5 21.5 21.8 20.5 20.1 22.3 18.4 12.8 27.1 24.8 17.9 21.2 15.5 14.6 13.1 45.8 21.6 13.7 29.9 20.0 17.3 29.5 27.1 56.0 20.4 13.8 25.4 25.7 32.6 18.5 28.0 19.7 18.7 10.8 58.3 20.9 22.4 25.4 14.3 22.7 3.8 20.8 25.7 19.4 43.3 40.4 77.6 12.8 20.3 85.4 21.3 10.4 30.4 51.9 30.2 40.3 71.4 24.6 11.3 45.2 60.0 26.9 10.5 39.9 16.4 16.2 19.6 57.7 13.7 26.6 32.9 27.6 27.0 53.3 28.8 17.0 24.7 104.8 19.4 33.8 15.3 17.9 SOS2 ENSG00000100485 "SOS Ras/Rho guanine nucleotide exchange factor 2" Q07890 14 50117130-50231578 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004577, HPA047368, HPA052689" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Vesicles "CAB004577: AB_628270, HPA047368: AB_2680014, HPA052689: AB_2681917" "unprognostic (7.99e-2)" "unprognostic (6.17e-2)" "unprognostic (7.80e-2)" "unprognostic (4.93e-2)" "unprognostic (2.81e-2)" "unprognostic (7.64e-2)" "unprognostic (1.56e-1)" "unprognostic (3.08e-1)" "unprognostic (2.01e-1)" "unprognostic (3.88e-1)" "unprognostic (9.99e-2)" "unprognostic (8.21e-2)" "prognostic favorable (8.48e-8)" "unprognostic (2.47e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (6.57e-2)" 23.8 14.9 15.3 15.3 21.4 39.5 17.9 18.2 19.5 14.3 13.5 17.4 21.5 15.2 22.4 16.4 12.7 12.9 21.5 14.0 16.8 24.5 13.2 15.8 14.4 19.7 18.6 15.3 15.9 39.3 9.1 17.0 19.1 15.4 17.3 14.0 14.5 18.7 57.6 17.9 24.5 18.0 16.8 17.8 13.7 27.9 19.6 16.5 25.1 63.8 13.5 14.8 10.5 23.9 15.3 11.1 22.1 14.9 16.6 18.0 10.4 13.5 14.8 10.0 12.5 4.9 19.8 16.0 11.9 17.3 17.3 13.8 12.1 10.2 17.7 26.9 4.4 16.1 8.5 8.5 18.3 19.1 16.6 18.8 24.6 9.3 21.6 25.2 21.8 13.1 12.5 39.0 24.2 12.7 15.9 15.1 6.9 11.4 9.6 17.0 30.8 12.1 16.1 14.4 16.0 18.7 15.0 17.5 17.8 15.9 19.4 23.0 24.1 27.3 17.8 12.5 8.9 27.3 31.7 19.6 7.1 10.5 16.4 8.0 1.1 2.8 1.1 0.9 0.9 0.6 0.7 0.8 0.8 0.7 0.8 0.7 4.6 1.7 2.0 1.4 0.0 0.4 15.3 21.4 18.2 19.5 14.0 16.8 19.7 18.6 19.1 16.8 19.6 23.9 34.1 9.6 26.3 59.4 18.4 35.7 20.9 10.5 10.2 17.2 23.8 15.6 43.7 17.2 18.2 18.4 16.7 8.2 46.3 36.0 7.9 11.3 17.0 18.7 30.4 23.5 20.4 6.3 71.5 10.7 8.0 22.2 12.8 29.8 20.3 37.4 22.9 13.8 8.8 25.2 89.6 18.5 12.2 33.3 17.5 8.6 12.5 29.0 17.8 80.6 29.0 17.6 21.6 100.5 104.8 14.5 24.6 13.5 28.6 27.3 28.6 15.8 14.3 22.5 19.7 43.4 30.8 54.3 12.3 17.7 39.6 13.0 24.2 17.4 14.9 30.6 SP2 KIAA0048 ENSG00000167182 "Sp2 transcription factor" Q02086 17 47896150-47928957 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003357, CAB010245" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm Vesicles "CAB010245: AB_2121523, HPA003357: AB_1080070" "unprognostic (1.23e-1)" "unprognostic (1.66e-2)" "unprognostic (6.30e-3)" "unprognostic (5.85e-2)" "unprognostic (1.18e-1)" "unprognostic (6.91e-2)" "unprognostic (5.66e-2)" "unprognostic (2.46e-1)" "unprognostic (6.46e-2)" "unprognostic (2.52e-1)" "unprognostic (1.44e-1)" "unprognostic (5.39e-2)" "prognostic favorable (1.82e-5)" "unprognostic (5.34e-3)" "unprognostic (4.28e-2)" "unprognostic (3.37e-2)" "unprognostic (8.66e-2)" 14.8 10.7 9.4 16.6 11.6 19.4 15.4 16.1 11.5 12.9 6.9 14.3 14.9 14.7 12.0 17.2 15.1 11.5 18.3 9.6 10.1 12.5 8.7 14.9 20.6 12.4 10.4 15.1 16.0 23.5 9.8 13.6 11.1 13.5 13.3 10.5 16.2 12.5 32.2 14.8 15.6 12.8 8.3 17.7 13.0 17.8 11.8 25.3 18.1 26.6 15.0 13.6 13.4 13.3 33.5 37.3 25.1 21.6 12.1 11.2 26.1 19.3 13.6 19.0 17.1 41.3 16.2 28.6 17.4 24.7 20.1 25.6 17.5 16.4 19.9 41.7 26.6 28.5 25.6 22.3 11.2 26.4 34.2 16.4 19.1 22.4 21.1 13.5 18.5 26.3 31.8 47.5 18.8 45.0 64.6 16.8 11.8 29.6 24.9 30.8 34.4 18.6 13.4 52.1 26.8 31.4 16.9 17.9 20.0 15.0 26.7 25.6 30.3 34.8 18.1 24.2 30.1 42.3 50.6 26.0 19.0 18.5 29.2 13.6 6.1 9.9 8.3 7.0 7.3 4.9 6.3 7.9 4.9 5.6 7.1 7.4 11.3 9.7 6.6 4.5 7.2 6.6 9.4 11.6 16.1 11.5 9.6 10.1 12.4 10.4 11.1 8.3 11.8 13.3 14.6 9.6 19.5 5.2 17.7 6.2 15.8 7.8 12.0 9.0 9.8 9.9 9.7 12.8 8.3 11.0 0.0 10.7 11.3 16.4 15.6 7.0 9.8 8.1 6.2 11.6 15.6 25.2 5.2 7.6 9.2 9.4 8.6 10.7 13.3 5.5 8.2 7.5 8.9 11.8 4.8 9.0 14.2 10.9 8.2 10.5 10.5 14.2 8.8 6.5 11.7 12.1 17.5 9.0 9.9 7.3 13.2 3.4 12.7 11.0 8.6 8.1 10.2 6.5 6.6 12.6 12.5 9.8 6.3 9.6 7.5 20.5 14.8 5.3 7.9 17.0 SPCS3 "FLJ22649, PRO3567, SPC22/23, SPC3, YLR066W" ENSG00000129128 "Signal peptidase complex subunit 3" P61009 4 176319966-176332245 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 670.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 374.4" "Low region specificity" "Detected in all" HPA053180 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA053180: AB_2682071" "unprognostic (4.30e-2)" "unprognostic (1.38e-1)" "unprognostic (5.20e-3)" "prognostic favorable (8.89e-6)" "unprognostic (1.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.50e-3)" "unprognostic (1.79e-2)" "unprognostic (4.78e-3)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.87e-4)" "unprognostic (2.58e-2)" "unprognostic (2.85e-1)" "unprognostic (2.26e-1)" "unprognostic (4.92e-2)" "unprognostic (2.16e-2)" "unprognostic (1.44e-1)" 33.0 24.6 13.9 50.6 16.0 68.1 36.0 15.5 18.0 46.6 15.1 37.0 34.5 38.5 47.5 25.0 25.5 32.0 37.6 17.3 17.1 34.1 43.6 36.1 50.3 15.9 25.6 21.6 72.8 31.3 30.1 45.5 16.1 32.9 37.5 13.5 99.1 30.0 24.1 26.9 36.9 34.8 18.1 46.5 48.9 10.7 16.3 34.8 62.2 26.4 48.2 41.1 25.6 21.2 64.9 21.5 57.8 47.8 80.9 142.5 61.0 125.2 119.1 71.4 61.4 23.5 139.1 124.2 25.1 72.7 37.6 43.6 55.3 92.1 108.0 84.2 24.3 107.6 32.2 53.5 82.5 162.3 90.9 86.9 99.4 63.4 60.9 79.8 107.1 59.4 70.2 374.4 99.4 39.7 100.1 61.4 39.5 45.6 21.0 48.7 89.8 109.3 87.7 46.5 46.1 42.2 130.6 96.4 58.8 49.8 31.1 75.1 100.2 52.5 52.8 47.4 58.2 172.3 54.7 153.8 112.0 80.6 74.1 43.0 16.1 14.2 15.2 19.3 20.2 10.0 14.0 13.9 12.2 6.8 11.6 14.5 16.2 16.6 16.1 22.6 11.9 19.2 13.9 16.0 15.5 18.0 17.3 17.1 15.9 25.6 16.1 18.1 16.3 21.2 121.4 54.5 86.3 19.2 150.0 57.2 67.4 111.8 25.0 31.3 62.9 52.1 79.5 32.9 84.1 29.5 27.1 64.1 170.0 55.2 21.5 76.4 66.8 49.3 130.6 109.3 44.9 61.4 40.9 136.1 205.1 66.2 70.3 102.2 91.2 36.3 88.9 123.8 153.2 23.5 37.3 102.1 89.5 100.8 98.4 14.4 22.4 127.9 110.3 29.0 105.8 31.2 74.2 41.2 59.1 157.0 36.0 17.0 670.6 173.8 48.1 71.6 54.5 31.0 13.1 46.4 64.8 95.4 56.4 58.7 65.1 184.4 107.0 51.8 53.3 147.1 SPRYD4 DKFZp686N0877 ENSG00000176422 "SPRY domain containing 4" Q8WW59 12 56468578-56479708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 20.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 147.2;Proximal tubular cells: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053469 Uncertain Approved Nucleoplasm NA NA 7500 "Cluster 11: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA053469: AB_2682162" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.00e-2)" "prognostic unfavorable (8.85e-5)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (3.06e-3)" "prognostic favorable (4.52e-4)" "unprognostic (5.59e-3)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (9.98e-2)" "unprognostic (1.27e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-1)" "unprognostic (3.44e-1)" "unprognostic (1.14e-1)" 1.5 3.7 1.6 1.6 1.4 2.8 3.1 3.2 1.9 2.0 0.7 2.5 2.0 2.0 3.0 3.1 2.0 1.5 3.3 1.4 1.6 3.7 20.5 1.4 1.8 0.8 0.8 2.4 6.0 2.5 3.7 1.2 1.0 2.6 3.2 3.4 2.7 1.7 4.1 2.4 2.2 1.7 0.5 2.3 2.5 1.5 1.3 1.4 2.7 5.1 1.7 2.3 2.1 1.2 2.1 2.7 2.3 1.8 2.0 1.3 3.1 1.7 1.7 3.5 2.1 2.5 3.6 2.6 2.2 2.2 2.4 3.5 2.0 2.9 2.2 1.3 4.1 3.8 3.1 3.8 1.9 2.6 3.7 2.9 1.9 2.5 2.1 1.9 3.6 1.8 2.1 11.0 3.0 3.4 1.3 1.9 1.5 2.4 3.1 1.6 1.7 5.4 3.8 2.6 2.3 1.1 3.3 3.9 2.6 1.4 6.6 0.8 1.7 1.5 2.8 2.2 1.4 1.8 1.1 0.9 1.2 2.2 1.9 1.0 1.0 0.5 0.7 0.7 0.8 1.0 0.7 0.7 0.9 1.0 0.7 0.7 0.7 1.2 0.9 1.3 0.3 0.7 1.6 1.4 3.2 1.9 1.4 1.6 0.8 0.8 1.0 0.5 1.3 1.2 4.4 0.0 7.4 2.0 7.9 4.8 16.2 24.8 10.2 13.2 14.1 12.7 17.7 18.6 16.2 22.0 16.7 38.3 5.8 17.3 54.8 26.6 1.4 4.0 7.5 8.9 17.5 19.1 0.9 21.4 24.3 8.1 14.8 9.8 10.2 10.7 10.0 147.2 20.8 16.8 1.6 14.6 28.5 12.2 2.3 1.1 9.0 6.4 5.4 1.9 11.1 10.2 8.2 2.0 2.2 18.5 10.1 10.5 6.3 10.8 19.5 101.5 5.9 17.8 0.0 8.1 8.6 5.1 10.2 22.2 5.3 36.0 4.4 30.2 16.4 19.8 SPTY2D1 "DKFZp686I068, FLJ39441, Spt2" ENSG00000179119 "SPT2 chromatin protein domain containing 1" Q68D10 11 18606403-18634791 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039372, HPA040177, HPA047957" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nucleoli" "HPA039372: AB_2676472, HPA040177: , HPA047957: AB_2680224" "unprognostic (8.43e-2)" "unprognostic (1.50e-1)" "unprognostic (8.62e-2)" "unprognostic (2.16e-1)" "unprognostic (1.73e-2)" "unprognostic (1.03e-1)" "unprognostic (1.51e-2)" "unprognostic (5.42e-2)" "unprognostic (1.74e-1)" "unprognostic (2.48e-1)" "prognostic unfavorable (2.59e-4)" "unprognostic (2.03e-1)" "prognostic favorable (2.07e-4)" "unprognostic (1.33e-2)" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" "unprognostic (3.33e-1)" 7.5 8.7 2.3 8.6 2.4 34.3 10.0 3.6 5.9 10.6 4.3 7.8 7.0 7.6 5.6 8.1 6.6 10.1 4.9 3.0 2.7 8.9 10.3 7.3 8.2 2.3 2.9 9.7 7.8 8.1 4.0 8.7 2.4 8.7 8.2 4.5 9.4 5.6 7.9 7.4 6.5 7.8 2.4 7.3 7.5 4.2 2.7 8.5 10.0 7.5 9.6 9.4 5.3 3.1 11.8 11.2 9.0 12.7 14.3 15.1 13.5 17.3 18.9 14.2 16.8 10.4 5.2 27.0 9.3 16.3 11.0 12.1 15.3 13.4 20.5 14.1 14.0 10.6 6.4 9.5 14.1 22.6 20.4 12.7 13.6 9.3 17.8 10.1 15.3 15.8 15.3 41.7 15.9 12.2 15.5 9.3 8.5 22.8 12.6 14.2 25.1 11.4 14.9 16.9 8.8 12.3 15.1 17.8 12.3 11.7 11.0 9.6 13.7 13.7 11.7 27.1 10.8 14.3 19.0 21.0 16.4 12.6 11.8 4.7 1.9 2.9 2.7 2.9 4.1 1.2 2.6 2.8 1.7 1.1 2.4 2.6 2.2 3.7 2.8 1.4 3.1 1.8 2.3 2.4 3.6 5.9 3.0 2.7 2.3 2.9 2.4 2.4 2.7 3.1 42.3 25.6 47.7 5.2 38.0 55.8 19.6 17.1 32.5 13.7 55.0 39.5 21.6 18.6 29.9 27.6 10.4 14.3 75.3 31.7 17.6 25.3 2.4 47.4 53.8 29.1 44.3 15.4 9.9 24.9 26.5 35.3 40.2 74.1 57.7 20.5 22.9 28.5 16.3 11.8 9.6 39.4 24.4 33.4 49.6 3.2 19.0 44.3 16.0 15.0 24.4 12.4 49.4 9.0 8.9 27.7 29.8 13.9 83.6 28.0 21.0 17.4 47.5 11.4 32.9 42.9 28.2 14.2 17.3 41.6 66.3 27.5 69.7 27.1 24.4 29.2 SSX1 CT5.1 ENSG00000126752 "SSX family member 1" Q16384 X 48255392-48267444 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 6.8" "Group enriched" "Detected in some" 4 "Spermatocytes: 24.2;Spermatogonia: 30.2" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Daudi: 66.1;Karpas-707: 90.5;U-2197: 22.7" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " "unprognostic (2.25e-1)" "unprognostic (3.51e-3)" "unprognostic (2.36e-1)" "unprognostic (4.32e-3)" "unprognostic (3.38e-1)" "unprognostic (5.41e-2)" "unprognostic (6.94e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.1 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 90.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 22.7 0.1 0.0 4.8 0.1 5.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 24.2 30.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSX3 CT5.3 ENSG00000165584 "SSX family member 3" Q99909 X 48346427-48356707 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 40 "testis: 13.5" "Group enriched" "Detected in some" 26 "Spermatocytes: 52.7;Spermatogonia: 118.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "Karpas-707: 2.1" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " "unprognostic (1.86e-1)" "unprognostic (2.13e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.7 118.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSX4 CT5.4 ENSG00000268009 "SSX family member 4" O60224 X 48383516-48393347 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 2.2;Karpas-707: 5.4;U-266/70: 4.5;U-266/84: 3.3" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.4 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 4.5 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ST3GAL5 "SIAT9, SIATGM3S, ST3GalV" ENSG00000115525 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" Q9UNP4 2 85837120-85905199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 47.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 112.8;Oligodendrocyte precursor cells: 94.0;Oligodendrocytes: 108.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 41.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 54.4;RT4: 47.0;SK-MEL-30: 40.8;U-266/84: 42.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034708, HPA040425, HPA068928" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA034708: AB_10601594, HPA040425: AB_2676978, HPA068928: AB_2686060" "unprognostic (7.90e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-2)" "unprognostic (2.93e-2)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (5.81e-3)" "unprognostic (1.38e-1)" "unprognostic (6.45e-2)" "unprognostic (5.03e-3)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.25e-7)" "unprognostic (2.22e-1)" "unprognostic (5.74e-2)" "prognostic favorable (4.99e-4)" "prognostic favorable (4.48e-4)" 17.5 47.4 17.1 4.6 26.9 2.3 8.5 16.4 20.1 5.4 7.9 5.0 1.0 9.9 0.9 2.7 10.4 8.1 4.2 16.0 24.7 2.8 9.8 14.6 9.1 24.7 22.6 10.1 3.9 0.4 12.8 17.7 23.1 6.7 2.6 31.0 7.1 0.5 12.4 6.1 6.9 3.5 20.6 20.0 5.6 10.8 23.6 5.0 27.9 3.5 4.4 20.8 5.9 41.6 0.3 27.0 2.5 54.4 22.0 11.8 8.0 5.9 18.0 5.6 5.0 0.5 19.6 0.7 0.2 10.2 2.5 1.0 3.6 6.4 7.0 0.2 3.2 0.6 1.1 1.0 17.6 0.4 7.8 6.9 0.8 2.1 0.8 10.1 13.7 7.4 0.8 30.2 18.3 1.8 1.9 3.1 0.2 9.6 0.0 3.5 17.0 11.0 2.9 47.0 3.8 3.8 0.2 0.1 40.8 5.4 0.2 1.1 4.5 0.1 2.7 0.1 0.4 30.0 42.5 0.5 4.2 5.6 27.7 0.6 0.8 0.1 0.6 3.0 0.8 1.1 0.3 0.4 0.5 0.7 0.3 0.3 0.6 0.6 2.4 0.2 0.1 0.3 17.1 26.9 16.4 20.1 16.0 24.7 24.7 22.6 23.1 20.6 23.6 41.6 8.5 86.6 112.8 37.5 29.1 5.6 27.6 20.5 1.2 56.6 3.1 2.3 1.9 40.0 33.9 3.7 58.4 0.4 48.3 0.2 3.9 12.0 12.3 9.0 27.8 8.1 6.7 0.4 46.9 16.6 1.1 21.7 6.1 8.5 34.8 35.2 29.6 21.1 35.6 72.3 60.2 0.1 12.2 45.4 18.1 12.0 8.1 24.9 32.0 45.9 20.1 56.0 12.3 94.0 108.4 6.2 0.1 1.9 19.5 6.8 0.0 3.7 10.7 45.2 0.0 21.3 5.0 8.4 16.1 0.2 3.8 0.3 28.9 6.3 0.1 8.3 ST8SIA4 "PST, PST1, SIAT8D" ENSG00000113532 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4" Q92187 5 100806933-100903282 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.0" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 73.3;Kupffer cells: 92.4;Langerhans cells: 149.3;Microglial cells: 101.2;monocytes: 97.5;Plasma cells: 73.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 91.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 41.1;HDLM-2: 69.3;Karpas-707: 57.2;NB-4: 27.9;RPMI-8226: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA051126, HPA053995" Approved Approved "Golgi apparatus" "Intracellular and membrane" NA NA 980000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA051126: AB_2681352, HPA053995: AB_2682336" "unprognostic (2.25e-1)" "unprognostic (2.04e-2)" "unprognostic (1.04e-1)" "unprognostic (1.98e-2)" "unprognostic (1.14e-1)" "unprognostic (6.45e-3)" "unprognostic (1.91e-1)" "unprognostic (5.46e-2)" "unprognostic (2.87e-1)" "unprognostic (1.49e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.80e-7)" "unprognostic (6.07e-2)" "unprognostic (4.38e-2)" "unprognostic (1.30e-1)" "unprognostic (1.23e-2)" 5.8 1.9 2.2 14.0 2.4 7.6 2.2 1.6 2.4 1.9 2.5 3.3 3.2 1.6 0.5 1.1 1.8 5.0 2.3 1.8 4.5 0.7 2.6 5.7 12.3 4.8 3.6 0.5 0.8 1.0 0.6 11.1 5.2 1.3 4.2 0.6 1.2 0.8 0.8 0.8 4.5 2.8 2.7 11.8 3.0 0.4 4.3 9.5 2.0 1.7 10.3 5.5 1.1 4.5 0.0 6.1 41.1 0.0 2.6 3.9 1.0 0.0 0.0 0.0 0.3 0.0 0.0 3.3 0.1 0.0 1.0 0.1 1.0 0.1 0.1 69.3 0.0 2.5 0.4 0.0 0.0 13.0 5.0 3.2 0.0 0.1 0.1 5.3 7.7 10.1 0.0 57.2 2.4 0.6 18.6 27.9 0.3 0.0 0.3 10.3 0.7 44.8 0.2 0.0 0.9 0.0 0.0 0.0 0.1 0.2 0.0 11.6 2.7 0.4 0.2 0.0 0.6 18.6 20.3 3.9 1.0 15.8 5.1 58.0 18.5 22.9 13.1 21.7 9.9 11.1 8.7 11.1 12.2 9.9 5.4 10.1 91.7 10.6 24.0 3.7 17.4 12.2 2.2 2.4 1.6 2.4 1.8 4.5 4.8 3.6 5.2 2.7 4.3 4.5 35.8 6.4 14.1 1.6 49.7 8.3 0.4 2.1 2.2 0.6 0.9 0.9 2.3 1.5 10.1 0.0 0.0 9.4 44.0 0.0 1.9 0.2 0.2 0.9 1.6 28.4 0.0 8.2 6.8 0.0 42.4 5.0 1.1 0.3 24.1 0.1 7.1 0.1 22.6 0.0 73.3 0.2 4.1 92.4 149.3 0.7 0.0 57.5 14.2 101.2 97.5 3.2 34.0 4.5 1.6 0.0 0.0 0.4 73.8 0.2 0.0 0.3 16.6 0.9 13.1 1.2 3.7 0.5 0.8 0.4 5.5 19.2 37.7 0.7 0.0 0.5 STAT4 ENSG00000138378 "Signal transducer and activator of transcription 4" Q14765 2 191029576-191151596 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.0;testis: 29.2" "Cell type enhanced" "Detected in many" "dendritic cells: 139.0;Early spermatids: 275.1;Excitatory neurons: 85.9;Late spermatids: 66.0;NK-cells: 108.1;Plasma cells: 83.8;T-cells: 137.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 76.6;T-cells: 121.2" "Cell line enhanced" "Detected in some" "Karpas-707: 58.8;U-266/70: 32.9;U-266/84: 12.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA001860, CAB013108" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB013108: , HPA001860: AB_1080104" "unprognostic (3.90e-5)" "unprognostic (1.30e-1)" "unprognostic (4.16e-2)" "unprognostic (6.45e-4)" "unprognostic (3.77e-2)" "unprognostic (4.79e-2)" "unprognostic (3.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (2.65e-1)" "unprognostic (6.02e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-1)" 4.7 4.0 3.4 11.5 4.4 15.7 3.0 0.1 10.4 1.6 0.1 2.8 4.5 1.9 2.6 1.4 1.6 5.1 23.0 3.8 3.6 4.5 9.5 7.8 18.0 2.1 1.7 1.5 2.2 1.2 15.0 2.6 2.0 1.8 3.4 2.1 2.2 1.3 1.2 1.1 6.9 1.4 0.6 15.5 4.4 29.2 3.4 9.0 2.4 1.0 10.4 5.9 1.8 4.5 0.1 1.7 1.1 0.0 0.0 3.6 0.3 0.6 2.2 0.6 2.2 0.4 0.8 0.0 0.2 2.8 1.6 0.9 0.0 4.7 1.2 0.0 0.8 1.3 0.0 0.0 0.6 0.0 0.1 1.5 2.3 1.1 0.5 0.1 0.0 6.0 0.0 58.8 0.2 0.0 3.5 0.0 0.3 0.0 0.9 0.0 0.0 4.3 0.2 0.1 0.1 1.2 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.1 0.1 1.6 0.0 32.9 12.8 0.0 1.2 0.0 0.1 15.7 0.4 0.1 121.2 0.8 107.3 1.8 71.6 101.2 0.6 1.0 68.1 95.8 2.8 76.6 0.8 9.3 28.1 55.3 3.4 4.4 0.1 10.4 3.8 3.6 2.1 1.7 2.0 0.6 3.4 4.5 2.9 3.2 4.2 2.6 14.5 1.3 0.6 2.9 0.0 0.9 0.9 1.1 20.3 4.3 0.6 1.8 8.4 0.4 139.0 0.5 0.0 0.6 275.1 1.1 0.5 1.2 0.0 10.5 85.9 0.2 2.9 2.9 8.6 0.7 1.3 0.8 1.1 1.1 1.1 0.0 59.4 0.3 0.0 6.3 10.6 66.0 0.3 14.4 5.4 7.5 6.3 0.0 108.1 6.0 2.4 0.1 0.3 0.4 83.8 1.0 0.0 0.8 2.4 0.2 0.0 0.6 3.7 8.3 1.2 0.4 1.7 0.5 137.4 0.1 0.3 0.7 STBD1 "FLJ41801, GENX-3414" ENSG00000118804 "Starch binding domain 1" O95210 4 76306733-76311130 "Plasma proteins, Predicted intracellular proteins, Transporters" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 130.3;skeletal muscle: 248.5;tongue: 154.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 9.1;Ductal cells: 7.9;Glandular and luminal cells: 5.1;Plasma cells: 7.0;Proximal enterocytes: 19.5;Respiratory ciliated cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 140.7;U-266/70: 62.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011952, HPA012849" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "HPA011952: AB_1847461, HPA012849: AB_1847460" "unprognostic (1.46e-1)" "unprognostic (1.02e-3)" "unprognostic (4.29e-2)" "unprognostic (1.95e-1)" "unprognostic (2.57e-1)" "unprognostic (4.72e-2)" "unprognostic (1.35e-2)" "unprognostic (6.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.03e-1)" "unprognostic (4.96e-3)" "unprognostic (4.42e-2)" "unprognostic (3.52e-2)" "unprognostic (2.93e-1)" "unprognostic (2.00e-1)" "unprognostic (2.84e-1)" "unprognostic (5.74e-2)" 109.7 5.3 4.3 7.3 4.0 19.9 11.8 3.5 6.3 7.0 2.9 29.0 9.6 9.3 3.2 15.1 13.7 12.8 52.7 4.0 7.0 10.0 130.3 14.1 1.3 6.7 5.4 10.0 12.0 7.9 1.7 16.8 6.2 20.7 26.4 4.0 4.7 13.9 248.5 1.5 26.1 28.0 5.6 2.2 15.5 9.7 5.6 1.3 2.6 154.7 2.1 22.1 4.5 5.6 15.9 9.9 2.0 10.0 46.3 13.9 12.7 21.9 21.6 12.0 12.6 12.6 17.9 0.0 13.1 25.8 26.2 9.2 9.6 6.1 7.4 52.4 3.6 1.7 18.2 16.5 4.8 9.5 10.5 7.1 24.0 10.2 8.2 32.4 0.9 0.0 0.6 140.7 23.7 13.0 0.6 7.4 2.5 24.1 7.2 0.0 3.8 9.9 8.0 17.2 2.6 17.7 12.9 20.2 0.3 5.0 4.9 3.7 3.9 11.6 5.9 29.4 12.5 62.8 17.1 0.0 19.6 7.5 5.4 0.1 2.6 5.7 2.0 3.1 1.1 0.1 2.4 2.4 2.5 0.0 0.5 0.9 0.3 4.4 1.2 0.3 0.8 1.3 4.3 4.0 3.5 6.3 4.0 7.0 6.7 5.4 6.2 5.6 5.6 5.6 0.0 0.0 0.5 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.2 9.1 0.0 7.9 0.0 2.8 1.5 0.1 0.0 0.4 0.0 3.9 1.4 1.0 2.6 5.1 0.0 0.3 0.0 1.5 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 3.3 2.9 0.0 7.0 0.5 19.5 0.3 6.6 0.0 0.0 1.1 3.0 0.2 0.0 1.1 0.0 0.8 0.3 0.3 1.4 0.9 STIMATE-MUSTN1 TMEM110-MUSTN1 ENSG00000248592 "STIMATE-MUSTN1 readthrough" 3 52833121-52897562 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 14.9;skeletal muscle: 9.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 8.8;Karpas-707: 5.8;PC-3: 6.5" HPA051855 Uncertain Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" Cytosol "HPA051855: AB_2681639" "unprognostic (4.19e-2)" "unprognostic (3.85e-2)" "unprognostic (5.95e-2)" "unprognostic (7.28e-2)" "unprognostic (5.35e-2)" "unprognostic (3.11e-4)" "unprognostic (4.73e-2)" "unprognostic (2.66e-2)" "unprognostic (1.59e-2)" "unprognostic (2.51e-2)" "unprognostic (1.57e-2)" "unprognostic (1.84e-2)" "unprognostic (6.01e-6)" "unprognostic (5.49e-2)" "unprognostic (7.31e-2)" "unprognostic (4.55e-2)" "unprognostic (5.09e-5)" 3.6 1.7 0.9 0.5 1.4 1.4 2.6 1.4 2.0 2.9 1.6 1.3 0.0 2.1 0.3 2.1 1.2 0.1 4.4 0.9 0.4 3.1 14.9 2.3 0.1 1.5 1.2 1.6 3.2 0.0 1.4 0.0 1.6 1.4 0.1 0.1 1.6 0.0 9.9 2.0 1.7 0.1 1.9 2.4 2.0 1.4 2.0 0.2 2.1 0.6 0.1 2.5 2.7 2.3 1.8 0.5 0.0 4.0 0.3 0.0 1.1 4.1 0.6 0.1 0.1 0.0 0.5 1.8 0.8 0.0 1.3 1.7 1.0 0.7 0.0 8.8 4.4 2.1 0.0 0.0 0.1 2.8 2.7 0.0 0.2 0.1 0.7 0.0 0.1 2.4 1.6 5.8 0.0 0.6 1.9 0.9 1.4 0.1 6.5 0.8 0.0 1.3 0.0 0.0 0.4 0.7 0.9 0.5 1.9 0.2 0.3 0.9 1.1 0.4 2.2 0.8 2.3 5.0 4.2 0.8 0.9 2.9 1.3 0.0 0.0 0.3 0.0 0.4 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.9 1.4 1.4 2.0 0.9 0.4 1.5 1.2 1.6 1.9 2.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STPG4 "C2orf61, FLJ40172" ENSG00000239605 "Sperm-tail PG-rich repeat containing 4" Q8N801 2 47045538-47155308 "Predicted intracellular proteins" "Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 23 "testis: 14.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047366, HPA052691" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" Nucleoplasm Cytosol "HPA047366: , HPA052691: AB_2681918" "unprognostic (6.74e-3)" "unprognostic (5.81e-4)" "unprognostic (3.43e-2)" "unprognostic (1.23e-3)" "unprognostic (1.72e-1)" "unprognostic (1.55e-3)" "unprognostic (4.36e-2)" "unprognostic (3.03e-2)" "unprognostic (1.41e-1)" "unprognostic (2.78e-2)" "unprognostic (2.36e-3)" "unprognostic (6.23e-2)" "unprognostic (3.64e-6)" "unprognostic (5.14e-2)" "unprognostic (6.00e-2)" "unprognostic (1.39e-1)" "unprognostic (2.53e-1)" 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.6 0.2 0.0 0.0 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 14.7 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.2 0.1 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.4 0.3 0.3 0.4 0.6 0.2 0.4 0.2 0.4 0.1 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SUB1 "p14, p15, PC4" ENSG00000113387 "SUB1 regulator of transcription" P53999 5 32531633-32604079 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 1838.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 1427.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001311, CAB015351" Supported Supported Nucleoplasm,Nucleoli NA NA 120000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Nucleoli" "CAB015351: AB_2197157, HPA001311: AB_1080123" "unprognostic (5.19e-2)" "unprognostic (1.58e-1)" "unprognostic (5.25e-2)" "unprognostic (1.71e-1)" "unprognostic (2.26e-1)" "unprognostic (6.87e-2)" "prognostic unfavorable (5.25e-6)" "unprognostic (8.31e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (3.46e-3)" "unprognostic (5.04e-2)" "unprognostic (1.95e-1)" "unprognostic (1.02e-3)" "unprognostic (2.12e-1)" "unprognostic (2.99e-1)" "unprognostic (2.43e-1)" "unprognostic (2.45e-1)" 142.0 98.7 88.7 130.4 100.7 251.7 122.1 72.7 152.6 109.7 69.4 110.0 88.7 85.4 83.3 108.9 66.0 74.1 113.3 104.3 98.7 129.2 135.3 91.2 159.8 80.7 87.2 68.3 62.0 107.3 88.4 103.2 94.7 73.2 107.1 83.6 76.6 65.4 105.2 69.6 83.7 79.4 86.0 144.9 97.3 71.1 92.6 204.2 69.2 108.9 137.3 124.0 73.2 85.3 199.9 161.8 315.3 295.8 187.5 329.1 197.7 340.3 245.4 300.8 275.4 236.9 307.3 101.2 231.0 236.5 307.3 132.4 266.9 278.9 402.9 420.2 244.1 337.8 365.8 450.5 264.4 594.6 441.4 233.3 235.6 321.0 228.0 166.0 228.9 378.5 399.4 1427.8 269.5 178.6 566.8 942.9 207.8 235.9 326.9 247.8 409.9 645.7 303.0 178.2 170.4 141.1 526.9 244.9 251.9 198.2 272.0 544.9 238.7 324.7 351.5 275.8 261.0 556.0 1035.0 180.5 297.7 634.9 202.4 650.7 135.8 326.2 164.7 142.3 151.4 330.4 215.9 219.8 265.1 214.8 168.2 195.2 163.7 155.2 133.4 390.1 344.6 326.1 88.7 100.7 72.7 152.6 104.3 98.7 80.7 87.2 94.7 86.0 92.6 85.3 298.9 144.2 163.4 27.1 638.2 584.9 588.7 709.9 324.4 118.1 459.2 383.9 196.7 244.5 320.1 310.8 43.8 493.0 613.5 342.1 1009.5 711.4 131.6 319.0 263.7 280.2 281.4 379.5 71.5 327.2 785.0 323.6 227.9 329.9 307.5 188.6 223.1 375.4 500.5 85.8 60.9 362.9 484.2 319.0 721.3 68.1 239.9 422.5 528.3 37.5 587.5 223.7 500.5 64.3 50.4 416.3 516.6 344.6 1838.8 536.0 342.4 921.2 291.9 79.7 203.8 224.0 468.5 447.2 439.9 411.8 565.4 836.8 575.5 357.7 394.6 645.5 SVOP DKFZp761H039 ENSG00000166111 "SV2 related protein" Q8N4V2 12 108907741-109021068 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 14.3;pituitary gland: 7.4;retina: 13.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 41.7;Early spermatids: 65.4;Excitatory neurons: 70.3;Inhibitory neurons: 75.8;Late spermatids: 121.5" "Group enriched" "Detected in some" 9 "glioma: 0.6;pancreatic cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Karpas-707: 2.8;RPMI-8226: 3.0;SCLC-21H: 1.5;SH-SY5Y: 1.3;U-266/84: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016573 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA016573: AB_2197027" "unprognostic (6.88e-2)" "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (6.51e-3)" "unprognostic (2.18e-2)" "unprognostic (3.79e-1)" "unprognostic (1.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "unprognostic (4.29e-3)" "unprognostic (3.07e-1)" "unprognostic (4.28e-3)" "unprognostic (3.94e-2)" "unprognostic (2.26e-2)" "unprognostic (6.17e-2)" 0.0 1.5 11.2 0.1 12.4 0.1 0.0 2.2 14.3 0.0 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 1.0 11.3 9.5 0.1 0.2 0.0 0.0 2.9 2.1 0.0 0.7 0.0 7.4 0.0 3.7 0.0 0.1 13.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.7 0.5 6.4 0.0 0.0 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 1.5 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 11.2 12.4 2.2 14.3 11.3 9.5 2.9 2.1 3.7 0.4 6.4 6.0 0.2 12.8 9.6 2.6 0.1 0.0 0.7 0.0 0.0 19.7 0.1 0.0 1.3 0.0 5.0 1.8 41.7 1.3 0.0 0.1 0.0 0.1 65.4 0.1 0.1 1.0 16.8 0.0 70.3 0.0 0.3 0.6 0.0 0.2 2.5 0.1 1.1 0.1 0.1 11.8 75.8 0.0 0.0 0.0 0.0 121.5 0.3 1.0 0.0 1.0 0.1 2.1 0.0 4.0 2.8 0.1 0.0 0.7 0.0 0.3 0.0 0.1 0.0 21.9 0.0 1.5 0.7 0.7 0.9 0.0 0.0 0.8 0.5 0.1 0.0 0.4 SYCE3 C22orf41 ENSG00000217442 "Synaptonemal complex central element protein 3" A1L190 22 50551112-50562919 "Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 46 "testis: 142.1" "Cell type enhanced" "Detected in many" "Early spermatids: 497.2;Late spermatids: 99.0;Spermatocytes: 508.0;Spermatogonia: 182.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.0;Karpas-707: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA047813 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA047813: AB_2797234" "unprognostic (2.55e-1)" "unprognostic (2.52e-1)" "unprognostic (2.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.63e-1)" "unprognostic (1.73e-2)" "unprognostic (2.22e-1)" "unprognostic (2.98e-3)" "unprognostic (1.68e-2)" "unprognostic (4.05e-2)" "unprognostic (3.43e-2)" "unprognostic (4.81e-2)" "unprognostic (2.57e-1)" "unprognostic (1.60e-1)" "unprognostic (1.55e-2)" "unprognostic (5.20e-2)" 0.4 1.1 1.7 0.5 1.7 0.3 1.1 1.7 3.0 0.4 1.5 0.7 0.2 0.0 1.6 0.5 1.2 1.0 0.3 1.7 1.8 2.8 1.8 0.6 0.5 1.9 2.0 0.0 0.4 0.6 1.3 0.3 2.1 0.4 0.1 1.3 0.5 0.1 0.1 0.5 0.2 0.0 1.6 0.2 0.4 142.1 1.8 0.8 1.7 0.0 0.3 0.5 0.2 1.8 0.2 0.4 0.1 0.1 0.3 0.3 0.2 0.3 0.0 0.1 0.0 0.0 5.0 0.2 1.7 0.0 1.0 0.0 0.5 0.5 0.0 0.0 0.2 0.0 0.4 0.0 2.1 0.0 0.9 1.3 1.1 0.2 0.8 0.2 0.0 1.0 0.0 4.1 0.2 1.8 0.0 0.0 0.2 2.1 0.0 0.0 0.0 2.3 0.6 1.5 0.4 1.3 0.0 1.2 0.9 0.2 1.2 1.0 0.0 0.4 0.4 0.0 0.0 1.0 0.2 0.7 0.5 0.1 0.1 0.0 0.7 0.8 0.0 0.6 0.1 0.0 0.0 0.0 1.1 0.2 0.0 0.1 4.3 0.0 0.5 0.0 0.0 0.1 1.7 1.7 1.7 3.0 1.7 1.8 1.9 2.0 2.1 1.6 1.8 1.8 0.3 0.0 0.0 0.0 0.1 0.1 0.4 3.7 2.8 0.8 5.6 5.6 0.5 2.8 2.1 1.8 0.0 5.9 0.1 0.4 3.9 1.7 497.2 2.7 0.4 0.7 0.0 0.0 0.1 0.6 3.2 0.2 0.0 2.0 0.0 0.0 0.7 3.2 1.7 0.0 0.1 0.1 4.1 1.2 0.0 99.0 10.8 0.8 0.0 0.0 2.9 1.2 0.0 0.0 0.2 0.9 0.1 7.2 0.0 0.6 0.4 7.6 4.7 0.8 46.0 0.0 0.7 508.0 182.4 0.8 0.1 3.7 0.1 0.0 0.2 0.8 SYCP3 ENSG00000139351 "Synaptonemal complex protein 3" Q8IZU3 12 101728648-101739472 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 146 "testis: 82.9" "Group enriched" "Detected in many" 8 "Spermatocytes: 825.7;Spermatogonia: 346.9" "Cancer enriched" "Detected in single" 16 "testis cancer: 5.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB032978, HPA039635, HPA043938" Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "CAB032978: AB_656732, HPA039635: AB_2676607, HPA043938: AB_2678740" "unprognostic (2.86e-3)" "unprognostic (3.91e-1)" "unprognostic (3.18e-1)" "unprognostic (9.61e-3)" "unprognostic (1.40e-1)" "unprognostic (1.22e-2)" "unprognostic (7.49e-2)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (2.86e-2)" "unprognostic (7.15e-3)" "unprognostic (7.81e-3)" "unprognostic (4.85e-2)" "unprognostic (1.93e-2)" "unprognostic (2.24e-1)" "unprognostic (4.07e-2)" "unprognostic (5.86e-4)" 0.0 0.1 0.3 0.3 0.4 0.2 0.0 0.5 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 82.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 1.3 0.2 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.2 0.6 0.4 0.2 0.0 0.1 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 2.0 9.1 4.5 0.0 0.7 0.4 1.2 2.2 0.9 0.6 1.3 1.5 0.3 1.8 0.0 0.4 3.1 0.6 0.0 0.1 24.1 0.3 1.3 0.9 1.2 0.4 10.1 0.4 0.2 0.7 0.0 0.7 3.8 0.3 0.7 0.2 0.6 0.0 10.7 0.7 0.0 1.0 0.3 31.2 9.0 1.7 0.0 0.0 0.4 0.3 1.0 9.5 1.8 0.3 1.9 1.9 2.0 0.9 1.0 0.3 0.8 1.7 65.7 2.0 0.4 825.7 346.9 0.7 0.3 0.1 2.0 0.2 1.3 0.5 SYNGR2 ENSG00000108639 "Synaptogyrin 2" O43760 17 78168581-78173527 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 434.8;monocytes: 836.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 672.3;OE19: 547.9;SK-BR-3: 630.6;T-47d: 502.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014742 Approved Approved "Golgi apparatus" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus" "HPA014742: AB_2669079" "unprognostic (2.19e-2)" "unprognostic (1.05e-3)" "unprognostic (2.84e-1)" "unprognostic (6.77e-3)" "unprognostic (9.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-3)" "unprognostic (4.98e-2)" "unprognostic (1.26e-2)" "unprognostic (1.20e-2)" "unprognostic (9.44e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (4.74e-2)" "unprognostic (5.21e-2)" "unprognostic (3.51e-2)" "unprognostic (1.78e-2)" 92.9 59.7 50.9 99.4 74.0 112.9 105.5 75.1 63.5 59.2 53.5 118.0 86.4 56.7 22.6 133.8 75.5 70.7 150.1 51.5 61.2 113.0 101.0 158.1 143.9 88.1 70.7 45.3 188.9 52.9 91.2 61.7 86.0 130.7 71.1 2.8 184.8 45.6 369.9 161.4 125.4 33.2 67.3 148.1 141.7 31.8 68.0 68.2 68.7 122.6 112.6 92.0 87.9 92.5 172.5 334.5 9.0 73.9 3.2 1.1 52.5 58.6 60.2 55.0 31.4 200.9 173.6 136.9 123.2 33.5 47.8 245.5 39.9 95.0 16.2 97.2 177.2 47.0 46.9 140.8 76.1 77.3 356.5 3.4 105.1 17.5 47.2 77.9 118.7 50.4 193.9 672.3 5.3 337.4 77.3 79.6 24.4 547.9 140.1 44.3 19.2 391.4 166.7 155.5 53.8 60.2 48.6 630.6 60.3 31.7 502.8 122.2 31.7 1.1 54.2 28.1 77.8 280.7 109.7 79.8 39.7 52.8 9.5 694.4 656.1 237.9 173.6 944.7 202.1 970.0 231.0 200.2 907.6 972.1 204.6 168.6 282.5 219.8 1139.9 530.1 314.6 837.0 50.9 74.0 75.1 63.5 51.5 61.2 88.1 70.7 86.0 67.3 68.0 92.5 56.1 128.2 113.4 3.3 226.6 124.1 136.1 170.9 79.1 3.3 126.5 84.1 63.0 68.6 153.2 171.0 6.2 169.7 63.1 125.2 9.8 313.6 3.6 41.2 9.6 83.5 72.6 70.2 2.4 434.8 59.1 27.9 104.5 89.7 103.0 25.3 56.4 46.9 255.5 5.0 1.2 327.6 193.3 137.9 330.6 4.9 22.1 150.3 74.7 16.9 836.7 5.1 24.7 2.5 31.3 286.5 160.9 17.0 159.2 282.4 77.5 36.2 63.4 3.9 39.5 26.0 46.2 13.4 12.3 120.1 163.4 179.5 58.8 11.4 212.8 216.8 SYT11 "DKFZp781D015, KIAA0080, MGC10881, MGC17226" ENSG00000132718 "Synaptotagmin 11" Q9BT88 1 155859567-155885199 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 148.8;retina: 68.6" "Group enriched" "Detected in many" 4 "Astrocytes: 91.1;Bipolar cells: 78.4;Excitatory neurons: 83.5;Horizontal cells: 89.2;Inhibitory neurons: 104.5;Muller glia cells: 135.6;Oligodendrocyte precursor cells: 113.1;Oligodendrocytes: 133.2" "Cancer enriched" "Detected in all" 12 "glioma: 117.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 184.0;SCLC-21H: 72.7;SH-SY5Y: 79.2;U-87 MG: 87.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064091 Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 5: Muller glia cells - Visual perception" "HPA064091: AB_2685189" "unprognostic (1.83e-1)" "unprognostic (5.99e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.93e-5)" "unprognostic (2.14e-1)" "unprognostic (8.02e-3)" "unprognostic (7.90e-2)" "unprognostic (4.43e-3)" "unprognostic (3.93e-1)" "unprognostic (1.16e-1)" "unprognostic (1.42e-2)" "unprognostic (9.65e-2)" "unprognostic (2.28e-2)" "unprognostic (1.66e-1)" "unprognostic (6.38e-2)" "unprognostic (1.10e-1)" "unprognostic (2.22e-3)" 8.0 19.7 94.1 8.8 113.2 3.8 5.0 112.8 126.8 14.0 3.8 13.9 3.4 17.3 11.9 5.4 8.6 11.3 13.4 105.2 106.7 5.1 1.7 7.9 11.1 107.0 108.8 13.4 3.1 1.6 37.1 9.8 107.7 11.8 6.6 68.6 2.4 16.4 2.5 2.4 6.7 19.4 113.2 10.2 6.1 5.7 124.7 3.0 3.5 5.4 9.2 10.6 9.4 148.8 0.1 0.7 47.2 1.1 33.6 17.9 0.2 8.9 24.1 9.3 16.7 0.1 1.3 9.4 3.9 32.2 14.3 0.6 4.0 0.1 13.9 46.0 0.9 9.1 1.3 0.1 9.6 5.1 26.9 11.2 0.0 33.7 0.6 52.5 30.2 0.3 0.1 184.0 12.8 0.1 0.5 2.5 30.8 0.0 0.2 1.9 4.7 0.2 1.5 0.0 72.7 79.2 1.3 0.1 11.1 0.9 0.1 1.3 22.6 17.4 10.8 11.9 11.4 48.7 25.4 18.8 87.2 0.1 13.6 6.1 4.9 0.1 16.9 5.9 4.7 1.9 8.8 11.8 7.0 1.5 0.8 8.8 2.5 7.8 8.5 0.4 17.2 8.3 94.1 113.2 112.8 126.8 105.2 106.7 107.0 108.8 107.7 113.2 124.7 148.8 25.3 0.0 0.0 91.1 3.2 0.5 0.2 0.2 0.6 78.4 0.5 0.9 11.4 0.0 0.1 1.8 22.9 0.1 23.3 0.0 0.0 1.4 0.1 0.9 12.0 20.3 4.8 3.4 83.5 1.0 0.2 9.3 2.0 1.9 12.0 16.0 7.1 0.4 4.7 89.2 104.5 0.1 0.0 9.4 5.2 0.7 2.8 11.2 3.6 23.4 13.6 135.6 19.6 113.1 133.2 1.4 0.0 15.8 5.5 0.4 0.1 1.2 1.0 13.7 19.7 7.7 15.9 2.0 1.0 0.1 1.0 0.0 14.3 2.1 0.0 0.3 TADA2B MGC21874 ENSG00000173011 "Transcriptional adaptor 2B" Q86TJ2 4 7041899-7057952 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 40.4;Rod photoreceptor cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035770 Approved Approved "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear speckles" "HPA035770: AB_10603993" "unprognostic (1.52e-1)" "unprognostic (1.50e-1)" "unprognostic (6.61e-2)" "unprognostic (2.77e-3)" "unprognostic (1.14e-2)" "unprognostic (1.70e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (2.99e-1)" "unprognostic (6.03e-2)" "unprognostic (8.91e-3)" "unprognostic (1.72e-1)" "prognostic favorable (7.17e-11)" "unprognostic (5.00e-2)" "unprognostic (1.58e-1)" "unprognostic (2.59e-2)" "prognostic favorable (1.59e-4)" 10.9 16.3 7.7 13.1 8.1 35.4 10.5 9.3 10.4 10.6 8.3 12.7 13.4 11.8 8.1 14.6 12.2 10.2 20.6 11.0 6.5 12.3 15.7 11.7 17.8 8.7 7.0 19.3 30.2 16.7 9.1 10.8 8.6 12.8 10.3 20.2 24.4 13.0 52.0 12.1 13.0 11.6 6.4 15.3 14.6 15.5 8.2 12.0 16.4 42.4 12.6 11.5 9.2 8.3 11.5 17.2 11.8 14.0 12.8 14.5 11.3 16.5 16.9 20.9 12.8 17.0 16.8 15.2 9.6 18.4 27.8 9.2 16.3 8.7 13.4 9.0 12.5 15.5 10.5 12.9 15.6 17.9 24.3 10.5 18.2 13.9 16.1 14.4 9.8 13.9 17.6 23.9 15.8 11.0 21.8 15.3 14.0 15.3 26.4 14.0 24.1 8.0 19.1 15.9 19.2 13.8 14.2 12.6 16.6 9.5 19.0 26.6 15.3 13.2 10.2 16.1 22.9 21.6 19.5 19.7 10.9 9.7 13.7 0.7 1.3 6.9 2.7 1.7 1.9 2.5 1.7 2.6 1.2 1.7 2.3 1.7 4.4 1.5 2.1 1.3 2.0 1.2 7.7 8.1 9.3 10.4 11.0 6.5 8.7 7.0 8.6 6.4 8.2 8.3 7.1 9.6 15.0 7.2 9.0 4.6 2.7 3.3 0.6 27.1 12.4 8.0 12.7 4.3 9.1 7.3 31.3 3.6 14.2 10.6 5.9 4.5 2.9 8.6 9.0 6.4 7.2 2.1 5.0 9.3 2.9 8.0 8.2 8.7 9.5 6.3 4.2 16.7 5.7 40.4 5.2 9.5 4.1 8.8 4.2 4.8 16.8 7.0 7.2 1.9 8.1 10.4 6.2 5.0 3.7 7.9 7.8 12.8 5.1 5.8 8.7 7.6 7.1 38.3 0.0 12.4 5.2 6.1 4.5 3.6 5.8 4.4 10.1 12.5 6.9 5.4 TANC1 "KIAA1728, ROLSB" ENSG00000115183 "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1" Q9C0D5 2 158968640-159232659 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 212.0;Microglial cells: 159.3;Oligodendrocyte precursor cells: 193.5;Oligodendrocytes: 223.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036750 Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA036750: AB_10670241" "unprognostic (2.93e-1)" "unprognostic (1.60e-1)" "unprognostic (1.56e-1)" "unprognostic (8.91e-2)" "unprognostic (2.43e-2)" "unprognostic (3.96e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.43e-2)" "unprognostic (3.94e-2)" "unprognostic (1.69e-2)" "unprognostic (1.20e-1)" "unprognostic (7.43e-2)" "unprognostic (3.07e-2)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (1.12e-1)" 9.1 5.9 9.7 3.9 14.0 0.2 7.8 15.8 7.5 10.2 8.1 9.2 6.4 10.9 2.0 12.7 5.8 7.5 22.1 13.0 15.8 6.6 4.4 12.6 3.3 18.4 13.6 6.3 5.9 5.9 3.5 13.4 18.1 7.8 7.0 12.0 7.1 4.4 2.7 20.5 6.5 12.9 11.9 5.0 5.9 1.9 21.1 3.6 10.8 4.3 4.8 8.6 6.8 20.0 8.7 7.4 18.4 14.3 16.7 7.1 9.0 6.6 13.9 6.6 10.4 8.0 9.5 0.0 22.6 21.2 5.0 18.7 5.9 26.1 8.4 0.0 13.7 5.6 11.8 1.5 19.7 0.7 14.3 11.0 21.3 12.4 23.1 30.1 35.8 8.5 1.4 39.8 11.1 3.9 5.5 0.0 2.4 9.8 6.7 0.7 10.0 12.9 15.2 34.9 2.8 18.9 14.5 6.6 34.9 11.4 7.2 5.6 33.8 14.7 8.6 3.1 6.1 19.7 14.5 0.0 8.2 0.0 40.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 14.0 15.8 7.5 13.0 15.8 18.4 13.6 18.1 11.9 21.1 20.0 42.1 28.9 17.1 34.9 0.2 48.9 13.5 21.7 46.7 30.1 19.3 16.9 64.7 15.7 23.5 11.0 6.2 2.9 0.9 18.9 3.9 13.3 1.1 11.1 12.1 48.3 0.0 4.2 9.9 12.5 3.8 16.0 33.1 11.7 17.2 47.6 35.3 8.7 2.0 212.0 54.7 16.6 10.2 2.8 10.3 1.7 10.5 1.7 24.9 159.3 0.6 48.6 1.0 193.5 223.7 13.4 22.7 4.9 1.6 14.4 10.5 4.9 12.5 4.9 13.1 11.6 27.5 0.5 2.1 38.6 42.1 2.1 2.5 14.6 14.9 17.3 TAPBP TAPA ENSG00000231925 "TAP binding protein" O15533 6 33299694-33314387 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 168.7;Karpas-707: 140.8;U-266/70: 140.5" "Low region specificity" "Detected in all" HPA007066 Approved NA NA 20000 "Cluster 49: Eosinophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 1: Pancreatic cells - Digestion" "HPA007066: AB_1857769" "prognostic favorable (2.76e-4)" "unprognostic (1.43e-2)" "unprognostic (7.01e-2)" "unprognostic (1.98e-2)" "unprognostic (1.59e-3)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (8.21e-2)" "prognostic favorable (6.29e-4)" "unprognostic (1.67e-2)" "unprognostic (2.37e-1)" "unprognostic (3.63e-1)" "unprognostic (1.61e-2)" "unprognostic (3.82e-1)" "unprognostic (1.19e-2)" "unprognostic (1.21e-1)" "unprognostic (6.54e-3)" 47.3 73.1 2.4 28.5 4.8 25.0 43.1 1.9 2.8 40.1 1.2 66.7 52.3 38.2 13.3 57.3 43.8 10.5 63.7 2.9 1.8 67.4 107.5 82.1 21.2 2.7 3.2 33.3 48.2 14.9 38.8 18.7 2.0 64.3 19.6 4.1 61.9 17.2 26.7 54.0 81.9 23.1 1.9 129.0 52.1 16.2 2.0 24.4 59.1 6.5 36.7 45.0 43.4 2.4 3.3 1.2 6.3 26.1 20.3 25.6 92.9 18.5 88.1 42.5 57.1 0.1 168.7 48.1 38.1 41.3 92.2 2.9 0.3 30.3 15.8 125.5 4.1 19.1 9.9 24.8 0.2 20.4 63.0 51.7 20.6 0.8 8.2 37.8 0.4 16.0 1.5 140.8 14.7 19.6 51.9 44.1 0.5 0.0 6.3 2.8 0.4 1.3 35.5 1.2 8.6 0.6 0.6 2.4 23.7 3.7 1.4 0.9 45.5 89.4 18.6 1.3 2.0 140.5 117.4 46.2 58.6 38.8 58.8 159.7 87.9 172.1 137.3 121.6 117.0 97.1 99.7 114.3 90.0 86.0 76.2 109.9 151.3 159.6 139.0 102.9 85.9 150.5 2.4 4.8 1.9 2.8 2.9 1.8 2.7 3.2 2.0 1.9 2.0 2.4 116.8 125.0 102.1 22.5 186.6 77.0 93.3 148.2 66.6 34.7 82.0 64.1 73.9 84.4 105.8 71.7 33.3 46.9 223.7 259.6 13.7 256.4 1.9 64.0 52.4 99.1 84.6 58.0 25.9 282.9 85.9 63.9 105.5 78.4 91.9 65.9 75.0 143.7 119.7 20.2 15.0 174.6 83.4 124.3 128.0 9.2 33.2 131.9 119.2 30.9 229.3 34.7 195.7 23.6 8.7 215.5 172.4 32.0 194.9 130.4 283.2 33.1 113.3 30.4 32.9 39.3 57.6 1.2 0.6 53.6 56.3 49.1 163.7 66.4 162.3 141.0 TCN2 "D22S676, D22S750, TC2" ENSG00000185339 "Transcobalamin 2" P20062 22 30607003-30627271 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Hepatic stellate cells: 137.4;Kupffer cells: 144.1;Proximal enterocytes: 563.6;Proximal tubular cells: 125.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 43.8;intermediate monocyte: 66.5;non-classical monocyte: 24.4" "Lineage enriched" "Detected in many" 8 "monocytes: 66.5" "Cell line enhanced" "Detected in many" "ASC TERT1: 117.6;HUVEC TERT2: 142.6;Karpas-707: 184.0;RPTEC TERT1: 70.7;TIME: 85.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000837 Approved Cytosol "Secreted to blood" NA NA 19000000 "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA000837: AB_1080235" "unprognostic (6.43e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.53e-3)" "unprognostic (3.17e-1)" "unprognostic (1.49e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.64e-4)" "unprognostic (1.52e-2)" "unprognostic (2.90e-1)" "unprognostic (1.07e-1)" "unprognostic (4.03e-2)" "unprognostic (1.59e-1)" "unprognostic (6.95e-3)" "unprognostic (4.94e-3)" "unprognostic (2.09e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" 49.6 30.6 24.6 16.0 24.1 5.5 37.9 25.5 30.6 25.9 27.1 23.4 23.6 28.7 20.3 8.6 21.5 50.1 28.7 22.7 25.3 115.8 17.3 37.7 35.3 27.1 26.1 14.8 12.1 8.6 15.1 18.6 27.7 16.0 27.8 11.1 13.2 45.4 6.0 9.0 59.5 36.8 25.5 46.7 17.4 21.9 29.7 6.4 26.4 13.7 10.0 22.0 14.7 25.3 0.2 9.5 41.8 0.2 24.6 117.6 1.4 3.1 30.9 8.0 13.1 4.6 21.2 0.6 45.7 6.2 0.7 1.5 3.7 2.2 2.5 0.0 2.3 0.2 1.2 2.0 58.5 0.6 33.7 19.8 2.5 6.1 5.1 8.8 142.6 0.0 0.8 184.0 12.7 0.1 0.1 3.3 16.4 11.7 1.0 4.9 6.0 64.2 70.7 1.1 14.4 1.9 0.3 0.6 12.0 2.8 0.4 2.0 85.3 26.4 3.5 3.3 1.3 5.1 1.4 0.2 9.5 1.7 0.6 0.0 43.8 0.0 0.1 66.5 0.7 0.0 0.8 0.4 7.9 0.0 0.3 0.6 1.4 0.0 24.4 1.5 0.2 18.8 24.6 24.1 25.5 30.6 22.7 25.3 27.1 26.1 27.7 25.5 29.7 25.3 105.0 3.2 3.9 3.9 3.7 5.2 2.2 4.7 0.6 8.0 7.1 5.1 6.5 27.1 13.7 12.9 20.9 0.4 0.5 70.9 7.9 7.8 1.1 3.5 5.4 64.6 6.7 0.8 0.2 6.0 0.8 19.5 5.1 6.2 4.5 23.4 137.4 5.6 45.9 1.7 1.9 28.6 4.1 144.1 9.4 1.4 10.5 53.8 23.2 8.4 8.8 7.4 0.0 5.5 1.7 5.1 50.2 9.8 13.5 2.0 563.6 125.8 2.8 29.1 13.1 0.9 5.5 1.0 12.6 0.5 5.3 0.4 2.2 5.6 21.0 2.7 TCTE1 "D6S46, DRC5, FAP155, MGC33600" ENSG00000146221 "T-complex-associated-testis-expressed 1" Q5JU00 6 44278734-44297698 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 14.4;testis: 30.0" "Group enriched" "Detected in some" 10 "Early spermatids: 161.8;Late spermatids: 359.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 1.0;U-266/84: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031739 Uncertain Vesicles NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA031739: AB_10601269" "unprognostic (3.27e-2)" "unprognostic (1.86e-1)" "unprognostic (2.04e-2)" "unprognostic (5.27e-3)" "unprognostic (1.55e-1)" "unprognostic (1.57e-2)" "unprognostic (7.06e-2)" "unprognostic (1.42e-2)" "unprognostic (3.46e-1)" "unprognostic (3.49e-2)" "unprognostic (1.17e-2)" "unprognostic (7.05e-2)" "unprognostic (2.23e-5)" "unprognostic (7.68e-2)" "unprognostic (3.13e-2)" "unprognostic (1.37e-3)" "unprognostic (2.68e-1)" 0.2 0.2 1.4 0.0 1.3 0.9 0.2 6.2 1.3 0.9 1.3 0.2 0.0 0.4 0.2 0.1 14.4 0.1 0.1 1.4 1.0 0.1 0.1 1.4 0.0 3.0 3.3 0.5 0.1 0.0 0.5 1.9 1.5 0.2 0.1 1.0 0.2 0.1 0.1 0.5 0.2 0.1 2.6 0.2 0.1 30.0 1.2 0.1 0.1 0.2 0.0 0.1 0.2 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.7 0.1 0.1 0.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.5 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.3 6.2 1.3 1.4 1.0 3.0 3.3 1.5 2.6 1.2 1.0 0.1 0.0 0.0 1.0 0.0 0.1 0.1 0.7 0.0 1.1 0.1 0.1 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 161.8 7.3 0.3 0.1 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 359.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.7 0.0 0.0 0.1 0.0 16.0 0.2 0.0 0.4 0.3 23.9 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 TENT5C "FAM46C, FLJ20202" ENSG00000183508 "Terminal nucleotidyltransferase 5C" Q5VWP2 1 117606048-117628389 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Nucleotidyltransferase, RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 89.1" "Cell type enhanced" "Detected in some" "B-cells: 41.8;Breast glandular cells: 34.0;Breast myoepithelial cells: 43.2;dendritic cells: 104.5;Plasma cells: 47.7;T-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 29.3" "Group enriched" "Detected in many" 17 "B-cells: 13.3;granulocytes: 29.3;T-cells: 13.7" "Cell line enhanced" "Detected in many" "Karpas-707: 296.2;RPMI-8226: 185.5;U-266/70: 81.7;U-266/84: 72.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054049 Uncertain Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA054049: AB_2682356" "unprognostic (3.76e-2)" "unprognostic (3.85e-3)" "unprognostic (3.24e-3)" "prognostic favorable (3.75e-5)" "unprognostic (1.17e-1)" "unprognostic (1.55e-3)" "unprognostic (3.29e-1)" "unprognostic (2.88e-2)" "unprognostic (5.75e-2)" "unprognostic (1.36e-3)" "unprognostic (9.41e-3)" "unprognostic (3.91e-2)" "prognostic favorable (2.77e-5)" "unprognostic (6.26e-2)" "unprognostic (3.16e-2)" "unprognostic (3.08e-2)" "unprognostic (1.10e-2)" 2.8 2.4 0.9 17.0 1.0 89.1 11.6 1.1 1.6 10.9 27.4 23.8 16.0 3.2 19.1 3.6 4.8 7.8 6.9 1.4 0.9 7.5 10.3 10.5 18.8 1.6 1.6 9.0 46.8 11.2 2.6 3.8 1.1 6.6 24.8 0.1 25.8 4.1 29.4 1.2 13.0 2.9 1.9 21.7 30.2 43.5 1.0 6.2 14.3 10.9 37.3 14.1 1.9 1.3 0.2 0.1 0.1 1.3 0.1 0.0 1.3 0.6 26.9 0.5 0.2 1.7 0.2 4.9 0.3 0.8 0.3 0.3 0.1 0.5 0.2 17.6 1.6 37.9 0.2 0.0 0.1 22.4 46.8 0.0 0.1 0.4 0.0 0.1 0.1 10.0 5.2 296.2 0.0 3.8 0.1 22.8 3.8 4.5 2.4 0.1 0.1 185.5 0.3 3.7 2.2 0.2 1.7 2.4 1.8 0.6 1.9 0.2 0.5 0.3 2.1 0.1 0.4 81.7 72.8 1.9 1.7 8.1 2.4 29.3 0.0 15.9 3.4 0.0 3.1 13.3 3.3 4.4 0.1 10.4 0.4 1.9 1.6 1.1 0.0 0.3 13.7 2.9 0.9 1.0 1.1 1.6 1.4 0.9 1.6 1.6 1.1 1.9 1.0 1.3 17.0 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 34.0 43.2 0.0 0.0 0.0 1.8 0.0 1.9 104.5 0.0 11.7 0.8 0.0 8.3 5.4 2.9 0.0 0.0 0.0 5.2 2.2 3.2 0.0 13.7 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 47.7 0.0 0.0 9.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 2.2 48.4 1.0 0.0 0.0 TESK2 ENSG00000070759 "Testis associated actin remodelling kinase 2" Q96S53 1 45343883-45491163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 222.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 14.6;RT4: 14.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027257, HPA063869" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA027257: AB_10602477, HPA063869: AB_2685137" "unprognostic (2.95e-1)" "prognostic favorable (2.22e-4)" "unprognostic (3.90e-2)" "unprognostic (5.04e-3)" "unprognostic (6.03e-2)" "unprognostic (1.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.43e-2)" "unprognostic (5.15e-2)" "unprognostic (2.96e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (4.36e-2)" "unprognostic (2.49e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-2)" "unprognostic (2.01e-1)" 3.8 2.1 7.1 2.8 10.6 10.2 6.6 10.3 8.3 6.4 4.8 5.3 8.6 3.2 3.7 7.1 3.0 2.6 2.4 7.3 8.0 2.5 6.9 3.9 3.9 10.8 10.1 9.8 3.6 3.4 2.4 3.5 10.3 15.5 7.0 2.8 8.4 2.6 8.3 12.7 10.8 2.9 8.5 5.3 4.5 9.6 9.9 4.2 3.4 4.7 5.2 4.7 7.4 15.1 1.9 0.0 0.9 0.1 3.5 1.8 14.6 0.7 4.9 2.1 3.6 4.3 1.7 6.2 0.6 1.8 5.4 2.3 3.9 3.1 1.6 4.4 4.9 4.2 2.0 3.2 1.9 1.4 11.1 1.9 3.2 2.4 3.4 3.2 1.7 8.1 0.8 12.4 1.4 0.7 3.6 2.9 3.8 1.8 1.8 5.2 0.1 1.5 1.9 14.7 0.4 1.6 3.8 7.3 14.1 8.6 11.3 1.8 0.0 0.2 2.1 1.3 1.3 8.0 5.0 1.2 1.1 0.0 1.0 12.8 4.6 13.3 2.7 3.4 1.9 8.0 2.5 1.8 2.4 6.6 4.1 2.3 19.0 1.5 8.0 1.3 1.9 3.4 7.1 10.6 10.3 8.3 7.3 8.0 10.8 10.1 10.3 8.5 9.9 15.1 3.9 0.0 2.8 54.2 10.7 7.8 7.1 2.8 14.2 2.4 11.9 9.4 1.3 4.3 3.4 0.0 14.6 8.3 4.2 13.9 0.0 1.3 23.7 4.6 1.8 3.2 4.2 5.0 10.2 2.7 2.8 3.7 7.7 8.9 7.0 2.4 2.2 6.3 6.8 0.0 6.7 6.9 4.1 5.5 4.4 7.8 2.8 6.0 3.6 15.9 4.6 1.1 4.1 18.6 222.9 1.1 7.3 1.9 9.8 10.6 14.9 1.2 2.0 3.1 6.6 2.6 6.1 22.0 13.6 12.6 8.5 14.8 4.7 1.8 4.9 8.0 TET2 "FLJ20032, KIAA1546" ENSG00000168769 "Tet methylcytosine dioxygenase 2" Q6N021 4 105145875-105279816 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 128.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 55.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 55.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043135 Supported Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA043135: AB_10794177" "unprognostic (6.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.69e-2)" "unprognostic (9.42e-2)" "unprognostic (4.15e-2)" "unprognostic (5.88e-2)" "unprognostic (6.12e-2)" "unprognostic (1.19e-3)" "unprognostic (1.15e-2)" "unprognostic (1.57e-2)" "unprognostic (5.77e-2)" "unprognostic (7.29e-2)" "unprognostic (2.70e-3)" "unprognostic (6.10e-2)" "unprognostic (1.89e-1)" "unprognostic (9.15e-2)" "unprognostic (7.84e-2)" 4.3 3.1 2.9 10.1 4.4 22.4 5.4 2.5 2.7 6.3 5.8 5.2 6.1 7.2 6.0 7.7 4.9 5.0 3.3 2.1 4.6 4.1 4.2 5.4 5.6 5.3 4.4 4.3 3.7 4.6 1.8 10.2 5.3 4.4 5.9 6.6 4.7 3.3 2.8 11.0 6.0 5.7 2.9 7.2 5.3 1.3 4.1 5.4 4.2 5.2 7.0 5.5 4.5 5.6 5.1 3.1 10.9 11.1 2.1 3.7 4.2 3.1 4.8 4.8 4.7 3.1 6.4 0.5 4.0 4.0 2.1 4.9 9.3 6.1 5.3 6.7 2.9 7.0 6.5 1.6 4.9 15.5 11.8 3.8 7.9 4.5 5.6 8.6 6.4 4.1 7.7 13.6 4.4 3.1 2.5 4.7 2.5 6.2 2.2 8.4 4.7 1.0 4.7 9.4 7.5 5.9 4.2 9.1 0.8 5.9 4.5 11.8 9.1 7.8 6.7 2.1 5.3 9.5 6.8 6.8 4.8 3.8 7.2 30.1 13.6 14.7 3.9 10.4 1.6 5.3 2.3 2.2 10.2 6.3 1.9 2.9 55.5 5.9 13.6 8.9 3.1 3.3 2.9 4.4 2.5 2.7 2.1 4.6 5.3 4.4 5.3 2.9 4.1 5.6 24.5 25.6 29.1 58.8 28.3 14.4 11.0 14.2 12.5 22.8 15.6 13.6 27.9 5.7 23.9 9.2 16.7 23.1 34.1 19.0 7.9 7.0 0.4 22.1 38.3 20.3 23.3 10.9 48.4 7.5 5.7 18.0 21.4 33.2 27.8 15.5 13.6 8.5 14.5 35.3 89.7 15.8 32.6 48.8 93.3 0.9 8.1 98.3 5.4 90.9 48.1 5.8 34.0 112.6 128.3 8.2 18.7 7.2 22.5 12.1 16.3 2.8 22.3 24.3 13.1 47.0 21.7 0.2 1.3 28.4 35.9 34.2 18.9 24.7 14.0 27.5 TEX14 CT113 ENSG00000121101 "Testis expressed 14, intercellular bridge forming factor" Q8IWB6 17 58556678-58692055 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 27.0" "Group enriched" "Detected in many" 4 "Early spermatids: 23.3;Spermatocytes: 56.4;Spermatogonia: 16.2" "Cancer enhanced" "Detected in some" "breast cancer: 0.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.3;Karpas-707: 7.9;MCF7: 3.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA030620, HPA077020" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Vesicles, Plasma membrane" "HPA030620: AB_10601598, HPA077020: AB_2732327" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-1)" "unprognostic (9.49e-2)" "unprognostic (2.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-1)" "unprognostic (6.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.61e-3)" "unprognostic (2.67e-2)" "unprognostic (8.10e-2)" "unprognostic (1.76e-9)" "unprognostic (1.77e-1)" "unprognostic (2.54e-1)" "unprognostic (5.00e-3)" "unprognostic (5.88e-2)" 0.1 0.1 0.5 0.1 0.6 1.7 0.2 1.1 0.6 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.5 0.4 0.2 0.2 0.1 0.5 0.5 0.3 0.1 0.0 0.2 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.1 27.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.1 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.2 0.0 0.1 6.3 0.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 7.9 0.0 3.3 0.3 0.0 0.4 0.1 0.1 0.3 0.2 1.2 0.0 0.1 0.9 0.1 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 1.1 0.6 0.4 0.5 0.5 0.5 0.5 0.5 0.5 0.8 4.4 0.0 0.0 2.9 5.7 0.9 1.8 0.7 2.8 0.6 4.7 7.2 1.3 5.7 1.5 1.8 0.0 1.6 0.7 0.1 0.0 0.0 23.3 0.4 0.2 1.5 0.0 0.0 2.2 0.0 1.0 0.7 0.5 1.8 1.3 0.2 1.4 0.8 3.7 0.0 2.2 0.5 2.0 0.6 2.3 6.4 0.3 4.6 3.6 2.8 0.0 0.6 1.0 1.0 3.0 0.1 0.0 0.4 4.3 0.7 0.0 0.1 0.2 1.3 0.0 1.2 1.5 56.4 16.2 1.7 0.1 1.1 0.7 0.0 0.0 0.4 TEX48 ENSG00000230601 "Testis expressed 48" A0A1B0GUV7 9 114666434-114682192 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "testis: 26.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Karpas-707: 5.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "unprognostic (2.70e-1)" "unprognostic (6.41e-2)" "unprognostic (7.83e-2)" "unprognostic (2.53e-1)" "unprognostic (5.10e-2)" "unprognostic (2.33e-2)" "unprognostic (1.70e-1)" "unprognostic (5.11e-2)" "unprognostic (1.51e-1)" "unprognostic (4.46e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.1 1.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 5.8 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TEX53 ENSG00000230054 "Testis expressed 53" A0A1B0GU33 9 114656304-114662374 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 61 "testis: 68.2" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.8" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "unprognostic (2.37e-1)" "unprognostic (2.17e-1)" "unprognostic (1.02e-1)" "unprognostic (8.79e-2)" "unprognostic (2.94e-1)" "unprognostic (2.85e-2)" "unprognostic (1.90e-2)" "unprognostic (6.83e-2)" "unprognostic (4.19e-2)" "unprognostic (8.18e-4)" "unprognostic (8.64e-6)" "unprognostic (9.94e-2)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 68.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 1.8 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TG "AITD3, TGN" ENSG00000042832 Thyroglobulin P01266 8 132866958-133134903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Thyroid hormones biosynthesis" "Hormone, Thyroid hormone" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 685 "thyroid gland: 9329.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 5.5;Cardiomyocytes: 3.0;Early spermatids: 2.3;Late spermatids: 2.2;Microglial cells: 1.9;Proximal tubular cells: 4.0" "Cancer enriched" "Detected in some" 1672 "thyroid cancer: 3072.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 2.1;HSkMC: 2.4;Karpas-707: 5.6;PC-3: 2.8;U-266/70: 2.0;U-266/84: 1.8" "Region enriched" "Detected in single" 5 "cerebellum: 1.1" "Low region specificity" "Detected in some" "CAB000077, HPA002740, CAB056155" Enhanced "Secreted in other tissues" NA NA 1600000 "Cluster 1: Neutrophils - Mixed function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB000077: , CAB056155: AB_2665573, HPA002740: AB_1080277" "unprognostic (1.18e-1)" "unprognostic (6.86e-2)" "unprognostic (7.40e-4)" "unprognostic (1.20e-2)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (7.38e-2)" "unprognostic (4.96e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-2)" "unprognostic (3.68e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (5.11e-2)" "unprognostic (3.64e-2)" 1.6 3.2 3.0 0.5 0.4 7.8 1.4 0.2 1.9 1.2 1.5 1.8 0.0 1.8 1.0 2.0 0.4 8.6 13.6 1.7 0.2 2.9 3.6 4.2 12.0 0.4 0.5 1.2 8.0 2.7 1.2 0.2 0.5 3.6 0.1 0.1 3.9 1.8 2.8 6.3 1.7 0.1 0.2 1.9 2.2 2.9 0.5 0.4 9329.0 0.0 0.6 0.6 1.7 0.5 0.0 0.0 0.0 0.0 0.5 0.7 0.3 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.4 1.7 0.6 0.0 0.5 0.0 0.7 0.0 5.6 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 2.0 1.8 0.0 0.1 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.1 0.1 3.0 0.4 0.2 1.9 1.7 0.2 0.4 0.5 0.5 0.2 0.5 0.5 0.3 0.0 0.6 0.3 0.2 0.0 5.5 0.1 0.0 0.0 0.1 0.1 3.0 0.0 1.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 2.3 0.3 0.1 0.4 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.4 0.4 0.3 0.0 0.7 0.3 0.0 0.0 0.0 2.2 0.0 0.1 0.0 1.9 0.7 0.3 0.0 0.5 0.1 0.1 0.0 0.4 0.1 0.5 0.0 4.0 0.0 0.0 0.0 0.3 0.3 0.8 0.3 0.0 0.6 0.0 0.2 1.1 0.0 1.2 THEMIS2 "C1orf38, ICB-1" ENSG00000130775 "Thymocyte selection associated family member 2" Q5TEJ8 1 27872543-27886685 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 215.5;lymphoid tissue: 126.0" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Hofbauer cells: 62.6;Kupffer cells: 135.9;Langerhans cells: 59.9;Macrophages: 125.4;monocytes: 144.8;Plasma cells: 57.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 403.3;eosinophil: 341.0;intermediate monocyte: 441.4;myeloid DC: 309.6;neutrophil: 498.1;non-classical monocyte: 454.6;plasmacytoid DC: 125.2" "Group enriched" "Detected in all" 6 "dendritic cells: 309.6;granulocytes: 498.1;monocytes: 454.6" "Cell line enhanced" "Detected in many" "Karpas-707: 135.9;U-266/70: 98.4;U-937: 62.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027513, HPA031096" Uncertain Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA027513: , HPA031096: AB_10599254" "unprognostic (7.38e-2)" "unprognostic (6.56e-2)" "unprognostic (5.07e-2)" "unprognostic (1.99e-3)" "unprognostic (4.51e-2)" "unprognostic (5.56e-3)" "unprognostic (4.13e-1)" "unprognostic (8.21e-2)" "unprognostic (1.77e-2)" "unprognostic (3.05e-2)" "unprognostic (1.38e-2)" "unprognostic (8.96e-2)" "unprognostic (7.21e-3)" "unprognostic (5.07e-2)" "unprognostic (1.42e-2)" "unprognostic (2.24e-3)" "unprognostic (4.52e-3)" 30.7 10.6 10.8 72.8 13.1 215.5 12.7 13.6 14.4 7.2 12.3 14.7 10.1 5.7 3.9 8.0 10.2 23.6 6.6 11.2 16.6 9.2 19.1 45.8 47.9 22.2 14.3 3.3 5.4 2.7 4.9 18.8 19.1 5.4 10.1 0.9 11.1 3.9 3.4 4.5 28.2 15.5 15.4 126.0 12.2 22.4 17.8 16.0 11.0 4.5 29.9 26.9 6.4 24.6 9.1 0.3 3.4 0.5 11.4 15.6 1.5 1.9 20.0 28.7 40.2 1.3 2.4 12.8 1.2 6.6 15.9 1.3 5.2 1.2 4.6 1.7 1.2 18.0 0.4 2.3 22.3 23.0 27.8 7.9 0.3 14.8 0.1 1.5 11.1 1.0 24.7 135.9 2.1 6.1 0.9 20.1 11.8 0.3 1.8 4.1 12.8 23.2 8.6 0.3 0.2 5.0 0.1 0.8 26.2 2.1 0.3 20.2 6.9 1.7 0.2 5.6 0.3 98.4 6.1 0.8 32.3 62.1 0.5 41.7 403.3 341.0 71.9 441.4 66.1 41.5 53.1 60.2 309.6 21.8 45.6 48.2 498.1 61.9 454.6 125.2 56.4 380.7 10.8 13.1 13.6 14.4 11.2 16.6 22.2 14.3 19.1 15.4 17.8 24.6 2.2 3.2 20.0 0.3 42.6 3.2 1.1 2.7 0.6 0.4 1.0 0.6 0.7 2.8 8.7 0.0 0.0 0.8 87.5 0.3 0.0 0.9 2.3 4.5 1.8 6.8 10.7 6.1 6.2 8.3 1.3 1.8 1.1 6.4 13.3 7.1 3.6 1.3 62.6 0.0 0.7 0.2 36.7 135.9 59.9 5.2 0.6 125.4 17.8 6.5 144.8 0.1 54.6 0.5 14.7 8.7 0.0 0.4 57.3 3.0 0.0 0.4 3.2 0.2 0.0 21.9 2.1 1.8 2.9 0.1 1.1 2.5 21.2 3.0 0.8 5.0 TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.0;placenta: 6.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 115.1" "Cancer enhanced" "Detected in some" "renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.0;Karpas-707: 9.6;PC-3: 3.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "cerebellum: 45.8" HPA060767 Approved Vesicles "Secreted to extracellular matrix" NA NA 560000 "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA060767: AB_2684357" "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" 3.1 0.5 0.7 1.0 5.9 0.0 2.7 20.0 8.9 1.8 0.0 1.2 0.6 1.1 0.3 0.7 1.3 2.4 0.7 9.9 5.4 1.6 0.1 1.2 1.0 3.5 6.9 0.3 2.3 0.8 0.9 6.4 4.4 0.9 0.9 1.8 0.8 0.8 0.4 1.4 1.8 1.4 0.0 0.0 0.7 0.4 3.0 0.3 1.4 0.4 0.8 1.6 1.5 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 1.3 0.0 0.9 0.0 0.0 9.6 0.0 0.0 0.0 0.1 0.9 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.9 20.0 8.9 9.9 5.4 3.5 6.9 4.4 0.0 3.0 1.1 10.2 0.0 0.6 0.0 0.0 1.8 0.3 1.3 0.6 14.1 0.2 0.1 7.1 1.5 1.8 0.0 0.0 4.4 0.0 0.0 0.0 1.5 0.1 0.0 2.0 18.9 0.0 0.0 24.9 2.0 1.4 2.4 0.0 0.1 0.0 0.0 2.5 0.0 0.3 8.4 8.0 0.1 0.0 0.0 1.0 0.0 3.1 0.1 1.8 10.3 0.0 0.1 0.0 115.1 0.5 0.1 0.0 4.5 0.0 1.1 4.0 1.1 0.8 0.7 0.0 0.2 0.3 0.1 0.2 0.1 1.7 1.9 0.8 0.0 0.6 0.2 TLNRD1 "MESDC1, MGC99595" ENSG00000140406 "Talin rod domain containing 1" Q9H1K6 15 81000923-81005788 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 36.8;Exocrine glandular cells: 31.5;Extravillous trophoblasts: 31.5;Glandular and luminal cells: 27.7;Hofbauer cells: 35.2;Pancreatic endocrine cells: 44.1;Proximal tubular cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "HDLM-2: 47.0;SK-MEL-30: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071716 Approved "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytoplasmic bodies" "HPA071716: AB_2732183" "unprognostic (1.32e-2)" "unprognostic (5.30e-2)" "unprognostic (9.29e-2)" "unprognostic (5.37e-3)" "unprognostic (9.10e-3)" "unprognostic (1.24e-2)" "unprognostic (1.61e-2)" "prognostic unfavorable (1.47e-5)" "unprognostic (1.68e-2)" "unprognostic (6.82e-2)" "unprognostic (1.81e-1)" "unprognostic (3.24e-1)" "prognostic unfavorable (1.87e-7)" "unprognostic (1.91e-1)" "unprognostic (1.44e-1)" "unprognostic (8.32e-2)" "unprognostic (3.82e-3)" 13.5 9.6 4.8 5.4 8.7 7.5 7.8 12.5 6.4 6.2 6.3 7.1 3.7 7.3 2.0 8.2 7.1 3.7 10.0 5.2 3.9 7.4 6.2 14.5 4.3 6.8 4.8 4.6 10.1 1.6 5.9 4.6 5.3 5.3 2.9 1.2 6.3 1.8 1.9 3.4 6.9 2.4 5.0 11.8 8.0 1.6 6.3 3.5 5.3 2.1 2.9 7.7 5.5 4.9 11.2 3.6 9.4 6.8 4.1 2.4 15.5 10.0 2.8 6.2 4.5 6.3 10.0 12.1 13.7 2.5 3.7 14.2 5.8 3.2 3.5 47.0 17.0 23.8 2.2 6.9 3.1 8.4 16.6 2.5 4.2 3.8 3.7 2.2 9.4 10.3 13.7 29.3 4.2 5.6 13.3 9.7 14.9 7.2 5.0 16.9 9.5 27.7 4.0 11.2 14.7 12.5 5.6 6.1 48.0 8.0 5.4 7.3 11.2 7.1 22.3 9.9 15.1 20.2 21.4 12.9 4.8 12.0 7.5 0.5 0.3 0.4 0.6 0.5 0.5 0.8 0.7 0.7 0.2 0.5 0.3 0.5 0.5 1.2 0.4 0.5 0.3 0.3 4.8 8.7 12.5 6.4 5.2 3.9 6.8 4.8 5.3 5.0 6.3 4.9 36.8 0.0 9.4 0.0 8.2 0.0 0.0 0.0 0.0 0.0 23.3 12.7 0.0 0.0 4.3 12.9 0.0 8.4 19.3 0.0 1.9 15.1 0.0 13.4 21.4 17.6 0.0 0.0 0.0 31.5 31.5 10.4 0.0 27.7 2.5 15.9 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 44.1 0.0 0.0 4.1 0.0 0.0 30.9 2.2 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.0 9.0 6.5 11.1 0.0 0.0 TLR4 "ARMD10, CD284, hToll, TLR-4" ENSG00000136869 "Toll like receptor 4" O00206 9 117704175-117724735 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Age-related macular degeneration, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 38.6;Astrocytes: 50.9;Hepatic stellate cells: 62.8;Hofbauer cells: 38.2;Kupffer cells: 106.0;Macrophages: 64.5;monocytes: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.8" "Group enriched" "Detected in many" 33 "dendritic cells: 22.4;granulocytes: 86.8;monocytes: 65.6" "Cell line enhanced" "Detected in many" "Karpas-707: 60.0;TIME: 43.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004025, HPA049174" Approved Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Golgi apparatus" "CAB004025: , HPA049174: AB_2680662" "unprognostic (1.60e-1)" "unprognostic (8.34e-2)" "unprognostic (7.22e-2)" "prognostic favorable (6.29e-4)" "unprognostic (3.39e-1)" "unprognostic (7.48e-2)" "unprognostic (8.68e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (5.18e-2)" "unprognostic (8.00e-2)" "unprognostic (9.42e-2)" "unprognostic (4.08e-2)" "unprognostic (8.63e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-2)" 31.1 11.0 12.4 25.7 15.7 22.3 12.0 11.7 8.3 6.5 1.7 6.7 4.3 5.6 1.2 4.8 4.8 10.8 8.4 10.3 17.8 6.8 16.7 16.2 13.1 12.3 14.0 6.0 2.6 2.5 2.1 23.9 12.4 4.6 7.3 2.9 6.0 3.2 3.1 3.5 5.8 10.8 14.9 32.6 4.4 1.5 14.2 3.5 5.5 12.0 7.7 13.3 2.7 10.1 0.0 0.0 25.5 0.0 11.1 23.0 0.1 10.2 17.9 2.5 1.5 0.0 2.6 3.6 0.5 26.7 7.5 0.1 0.0 2.2 3.7 0.0 0.0 5.7 5.1 0.4 8.1 19.1 0.1 14.2 0.0 5.4 0.7 22.5 31.4 0.0 0.0 60.0 29.2 0.0 0.0 2.9 3.1 2.4 1.2 0.0 28.0 19.8 0.9 28.9 0.0 0.1 6.4 0.0 1.0 2.2 0.0 10.4 43.5 1.4 18.4 0.1 4.8 0.0 0.0 0.0 0.9 19.1 15.2 64.0 64.9 21.5 0.1 57.5 0.0 1.7 0.1 0.0 22.4 0.5 0.0 0.0 86.8 0.1 65.6 0.9 0.0 25.5 12.4 15.7 11.7 8.3 10.3 17.8 12.3 14.0 12.4 14.9 14.2 10.1 38.6 0.0 5.0 50.9 2.3 0.8 0.3 0.1 0.6 0.2 3.5 1.0 2.9 2.8 2.9 0.0 0.0 0.3 0.1 1.6 0.0 0.1 0.1 3.5 29.2 31.6 0.0 1.3 0.2 0.2 0.2 11.5 1.5 6.8 15.8 1.2 62.8 1.9 38.2 0.0 0.2 2.0 0.0 106.0 8.6 0.4 0.0 64.5 1.8 26.2 54.0 8.8 2.1 7.5 0.3 0.5 6.1 0.0 0.1 0.1 0.0 0.4 3.7 1.3 6.6 5.5 4.5 0.1 0.3 0.3 0.0 0.8 0.9 3.1 1.2 3.3 TMCC3 KIAA1145 ENSG00000057704 "Transmembrane and coiled-coil domain family 3" Q9ULS5 12 94567122-94650557 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.3" "Cell type enhanced" "Detected in many" "Adipocytes: 81.2;Distal enterocytes: 98.3;Microglial cells: 70.3;Oligodendrocytes: 119.8;Paneth cells: 70.1;Urothelial cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 46.9;neutrophil: 69.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 69.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 31.3;Karpas-707: 41.9;U-266/84: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014272 Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA014272: AB_1858059" "unprognostic (1.03e-1)" "unprognostic (2.54e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (4.87e-4)" "unprognostic (1.30e-1)" "unprognostic (8.63e-2)" "unprognostic (5.87e-2)" "unprognostic (1.17e-2)" "unprognostic (9.12e-2)" "unprognostic (3.45e-3)" "unprognostic (1.24e-1)" "unprognostic (7.73e-2)" "unprognostic (1.80e-3)" "unprognostic (9.11e-2)" "unprognostic (2.32e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" 11.7 4.5 13.6 9.4 25.8 10.0 9.6 23.1 16.5 11.6 3.9 22.5 14.9 7.7 3.1 6.1 5.7 5.3 2.3 13.2 19.6 8.1 4.1 5.3 4.4 26.9 25.9 4.7 3.2 4.6 3.4 17.8 26.7 8.3 16.4 0.9 2.8 5.4 18.4 6.1 21.0 7.9 20.8 12.2 7.3 2.0 24.8 4.0 13.3 7.0 6.3 7.5 4.8 36.3 7.8 0.4 1.9 0.0 0.7 2.7 13.6 0.0 0.0 0.5 1.9 0.0 1.7 0.2 0.1 0.0 6.8 19.1 10.7 12.9 2.6 3.5 2.6 5.1 0.8 0.0 0.5 0.0 10.2 1.7 1.7 7.2 10.1 11.3 31.3 0.0 0.2 41.9 1.0 0.4 0.0 0.4 1.0 2.7 6.5 0.0 0.6 5.1 2.0 16.4 0.2 0.8 0.2 8.0 0.4 8.8 0.0 0.4 19.0 0.0 0.2 0.1 3.4 19.4 30.1 0.3 3.9 1.6 1.7 16.4 4.3 46.9 3.3 6.0 0.3 5.4 1.2 1.9 2.5 3.1 0.0 2.2 69.7 3.3 7.8 2.8 0.0 3.1 13.6 25.8 23.1 16.5 13.2 19.6 26.9 25.9 26.7 20.8 24.8 36.3 81.2 0.0 2.7 2.9 5.7 20.6 32.7 3.2 9.6 4.4 2.1 1.3 2.0 4.3 3.2 7.3 0.0 16.0 16.3 98.3 0.0 1.9 5.8 24.5 3.6 31.9 12.0 0.0 0.6 3.8 3.2 4.8 10.2 39.8 0.0 17.1 31.8 0.6 4.1 0.0 15.0 13.0 0.0 15.0 9.2 8.3 1.8 20.3 3.6 70.3 19.0 0.1 11.3 11.6 119.8 12.9 70.1 1.2 7.8 16.8 48.1 8.9 3.0 0.3 6.6 19.7 6.1 0.0 2.2 30.4 16.2 7.1 7.7 2.5 8.2 83.3 TMEM109 MGC5508 ENSG00000110108 "Transmembrane protein 109" Q9BVC6 11 60914158-60923443 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011785 Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear membrane, Cytosol" "HPA011785: AB_1858075" "unprognostic (5.23e-2)" "unprognostic (9.02e-2)" "unprognostic (2.46e-2)" "unprognostic (2.69e-2)" "unprognostic (1.23e-1)" "unprognostic (2.40e-2)" "unprognostic (5.29e-3)" "unprognostic (2.95e-1)" "unprognostic (2.70e-1)" "unprognostic (2.40e-2)" "unprognostic (2.52e-1)" "unprognostic (3.63e-2)" "unprognostic (1.83e-1)" "unprognostic (2.82e-1)" "unprognostic (1.51e-1)" "unprognostic (2.84e-2)" "prognostic unfavorable (2.68e-4)" 83.0 46.4 22.2 44.4 23.2 27.0 71.9 23.3 25.5 85.4 42.1 75.1 26.2 97.7 26.7 93.8 73.7 35.7 84.0 19.8 23.2 47.3 32.1 71.8 48.0 26.7 24.5 81.5 46.1 67.3 41.1 46.8 25.4 52.4 27.0 14.3 81.8 60.8 99.4 69.7 47.8 70.0 25.9 58.1 58.2 14.4 25.5 41.4 57.3 77.0 50.3 70.4 79.9 24.7 111.5 103.5 63.3 102.1 169.4 77.7 51.5 107.3 100.4 118.5 99.8 94.5 115.7 131.5 190.4 130.1 69.9 143.5 73.2 48.8 72.5 102.5 97.0 96.2 44.3 21.1 50.2 188.4 77.0 54.1 61.6 92.9 46.8 41.9 148.1 104.8 48.4 330.4 85.4 217.2 139.9 80.8 104.6 62.8 111.4 132.3 123.9 183.0 56.6 63.6 25.3 44.4 86.2 196.8 102.7 44.8 110.4 35.8 143.7 136.9 65.9 174.4 95.8 108.7 89.5 69.9 121.2 82.0 159.7 39.0 76.0 56.4 188.7 69.5 193.3 116.5 108.4 161.4 227.4 140.4 97.4 124.8 8.2 121.1 52.4 470.0 91.1 139.4 22.2 23.2 23.3 25.5 19.8 23.2 26.7 24.5 25.4 25.9 25.5 24.7 118.2 70.5 23.2 5.5 60.2 50.7 43.8 30.9 63.7 13.4 39.5 45.3 34.6 25.8 23.9 25.8 0.0 120.7 83.4 6.8 25.4 76.6 20.7 18.7 25.9 91.2 7.2 33.0 5.3 80.2 116.4 75.9 10.7 27.9 50.7 22.2 71.0 18.9 66.8 30.3 3.8 10.1 22.4 21.3 69.1 11.1 89.5 43.4 51.6 11.2 45.4 30.2 68.0 3.5 5.1 53.1 14.7 97.4 38.4 36.5 10.6 17.1 18.7 34.8 39.5 45.0 67.6 5.9 7.2 55.1 50.6 53.2 52.7 25.8 16.8 33.9 TMEM205 "MBC3205, UNQ501" ENSG00000105518 "Transmembrane protein 205" Q6UW68 19 11342776-11346518 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 405.8;Hepatocytes: 520.1;Late spermatids: 662.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041504 Approved Approved "Nucleoplasm,Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "Nucleoplasm, Nuclear membrane" "HPA041504: AB_10795595" "unprognostic (2.54e-2)" "unprognostic (2.60e-2)" "unprognostic (7.19e-2)" "unprognostic (1.57e-2)" "unprognostic (6.83e-2)" "unprognostic (1.80e-1)" "unprognostic (5.04e-3)" "unprognostic (3.77e-2)" "unprognostic (1.01e-2)" "unprognostic (5.56e-3)" "unprognostic (2.70e-2)" "unprognostic (1.19e-1)" "unprognostic (8.10e-2)" "unprognostic (5.78e-2)" "unprognostic (8.18e-2)" "unprognostic (1.20e-1)" "unprognostic (1.45e-1)" 70.3 177.5 111.5 36.8 113.2 55.2 76.0 110.7 142.9 92.8 135.4 73.8 62.3 69.5 92.6 53.7 85.2 61.1 119.7 117.2 122.4 139.2 276.9 73.9 38.9 112.8 113.1 86.8 155.0 210.0 97.4 53.6 114.0 93.2 36.4 25.9 92.4 78.7 122.2 74.3 57.2 42.2 113.6 62.6 86.3 78.8 113.6 39.3 132.1 66.0 34.1 92.4 64.0 122.7 95.5 229.7 28.5 96.2 54.1 64.5 52.6 35.2 80.9 75.9 59.4 70.0 29.5 84.7 209.3 71.6 74.5 95.6 40.5 106.6 50.5 100.7 39.2 23.0 76.5 117.7 135.9 38.9 69.8 61.3 106.7 48.7 81.0 78.5 92.3 79.9 70.4 349.8 47.0 238.8 58.6 108.9 49.9 123.0 174.5 54.3 43.4 225.9 186.9 169.0 50.2 76.7 37.3 151.1 88.1 33.1 132.2 111.3 54.0 94.3 36.2 104.4 80.2 207.0 225.3 51.5 90.4 172.2 74.0 31.8 336.5 36.7 67.2 150.0 67.9 112.7 54.7 58.5 208.2 95.8 43.9 52.2 52.6 55.8 91.0 150.9 73.7 175.8 111.5 113.2 110.7 142.9 117.2 122.4 112.8 113.1 114.0 113.6 113.6 122.7 80.5 67.3 70.5 40.1 44.1 51.5 135.9 281.3 62.0 32.5 113.3 134.4 68.5 175.8 202.3 152.6 12.5 123.7 27.7 53.7 60.7 159.2 405.8 63.2 65.8 72.4 117.6 14.5 30.8 162.7 83.0 76.4 26.0 97.0 29.2 45.4 69.3 520.1 94.4 26.9 27.3 81.4 136.3 67.5 50.0 662.3 80.8 61.2 96.0 5.6 62.1 91.9 19.6 17.6 22.2 97.7 68.6 68.1 70.7 136.7 104.1 224.6 69.3 33.1 46.0 76.3 70.9 38.1 15.6 46.4 54.0 96.7 29.8 101.6 79.3 130.9 TMEM225B ENSG00000244219 "Transmembrane protein 225B" P0DP42 7 99598267-99611045 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "testis: 137.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.0;Breast glandular cells: 3.0;Breast myoepithelial cells: 3.0;Exocrine glandular cells: 2.5;Granulosa cells: 2.9;Proximal tubular cells: 2.0;Theca cells: 5.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 11.9;U-266/70: 6.6" "Low region specificity" "Detected in many" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.91e-3)" "unprognostic (5.04e-3)" "unprognostic (1.04e-1)" "unprognostic (1.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.95e-1)" "unprognostic (6.27e-3)" "unprognostic (2.75e-2)" "unprognostic (1.11e-1)" "unprognostic (2.58e-2)" "unprognostic (1.25e-1)" "unprognostic (7.08e-2)" "unprognostic (1.62e-1)" "unprognostic (4.00e-1)" "unprognostic (6.86e-2)" "unprognostic (1.17e-1)" "unprognostic (2.50e-1)" 3.5 2.0 2.3 0.2 2.6 0.3 3.1 2.2 4.0 2.3 1.9 1.2 0.3 1.9 3.5 1.4 2.4 1.0 0.7 2.3 2.6 3.5 0.7 1.4 0.6 2.7 2.4 1.5 1.3 2.5 2.9 1.3 2.5 2.2 0.5 0.7 1.7 1.4 0.8 3.9 1.2 0.8 2.5 1.2 1.1 137.0 2.5 1.8 2.5 0.0 1.1 1.5 2.0 2.9 1.1 1.5 0.8 0.2 3.8 1.0 0.0 0.5 2.6 1.4 1.6 0.1 0.9 1.2 0.0 0.0 0.5 0.1 0.4 0.0 2.9 3.8 0.6 0.2 0.0 0.3 1.2 0.9 0.8 0.3 0.5 0.1 2.3 5.1 0.0 1.9 0.6 11.9 0.6 0.0 2.0 4.6 0.1 0.0 0.0 0.7 1.1 1.7 0.4 0.1 0.5 1.1 0.3 0.0 0.4 0.6 0.0 0.6 0.0 0.5 1.7 3.7 0.2 6.6 1.6 2.3 0.6 1.4 1.1 0.0 0.0 1.3 0.6 0.1 1.1 1.0 0.8 0.4 0.5 2.2 0.8 1.4 0.3 1.3 0.2 1.4 0.6 0.6 2.3 2.6 2.2 4.0 2.3 2.6 2.7 2.4 2.5 2.5 2.5 2.9 0.5 0.0 3.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 3.0 0.0 0.0 0.6 0.0 0.0 1.2 0.8 0.0 0.0 1.1 0.0 0.5 0.8 0.1 0.0 0.0 0.0 2.5 0.4 1.0 0.0 0.5 1.3 2.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.6 0.2 5.4 0.0 0.0 TMEM268 "C9orf91, DKFZp547P234, FLJ38045" ENSG00000157693 "Transmembrane protein 268" Q5VZI3 9 114611206-114646422 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 10.3;Breast glandular cells: 8.8;Endometrial stromal cells: 8.9;Glandular and luminal cells: 8.8;Granulosa cells: 9.6;Hofbauer cells: 8.9;monocytes: 19.1;Syncytiotrophoblasts: 8.8;Theca cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 51.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017199 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA017199: AB_1845845" "unprognostic (8.57e-2)" "unprognostic (3.37e-1)" "unprognostic (8.33e-2)" "prognostic favorable (3.61e-4)" "unprognostic (2.09e-1)" "unprognostic (7.16e-2)" "unprognostic (3.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.87e-1)" "unprognostic (2.26e-2)" "unprognostic (2.22e-3)" "unprognostic (1.44e-1)" "unprognostic (6.67e-2)" "unprognostic (6.10e-2)" "unprognostic (7.65e-3)" "unprognostic (1.09e-2)" "unprognostic (1.47e-1)" 7.3 7.7 11.0 6.9 12.7 3.6 7.5 2.9 16.6 6.5 6.4 6.9 3.4 6.8 6.3 4.3 4.7 3.7 3.3 14.4 6.1 3.3 5.3 5.2 9.5 4.4 5.3 8.5 4.7 14.1 4.1 4.8 5.3 12.2 5.4 4.5 8.9 6.5 4.6 4.2 6.3 6.8 5.3 13.3 7.2 3.9 6.5 8.6 6.2 4.3 9.4 6.3 5.1 11.3 4.7 7.1 3.8 8.2 10.1 7.6 2.9 4.3 7.9 6.0 6.1 5.1 2.0 19.5 3.5 4.8 17.0 8.1 7.4 3.7 5.2 9.9 4.6 6.5 5.8 4.0 17.9 13.6 3.0 6.7 6.5 7.8 8.4 7.7 4.1 24.9 12.3 51.5 4.4 13.6 15.4 4.5 9.8 6.0 7.8 17.4 4.5 17.7 3.5 3.4 12.5 8.4 14.4 18.8 41.3 2.4 25.2 12.2 2.5 6.0 6.8 2.3 8.3 27.8 27.5 20.7 3.1 11.4 11.0 0.3 1.3 0.2 0.6 1.0 0.2 1.3 0.7 0.4 0.7 2.2 0.9 0.8 1.0 0.8 1.0 4.7 0.1 0.5 11.0 12.7 2.9 16.6 14.4 6.1 4.4 5.3 5.3 5.3 6.5 11.3 1.7 0.0 10.3 0.0 3.8 0.0 0.0 0.0 0.0 0.0 8.8 5.2 0.0 0.0 1.3 0.0 0.0 4.7 3.0 0.0 0.0 1.4 0.0 5.0 8.9 0.5 0.0 0.0 0.0 4.6 1.2 1.3 0.0 8.8 0.0 9.6 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 19.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.6 0.0 0.0 1.9 4.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 8.8 1.1 9.7 0.0 0.0 TNFAIP3 "A20, OTUD7C" ENSG00000118503 "TNF alpha induced protein 3" P21580 6 137867214-137883312 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Inflammatory response, Ubl conjugation pathway" "DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 519.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 774.9;Endometrial ciliated cells: 605.2;Glandular and luminal cells: 1498.3;Macrophages: 596.6;Suprabasal keratinocytes: 745.7;T-cells: 624.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 106.5;Karpas-707: 161.3;REH: 151.5;U-266/84: 131.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002116 Approved Approved Centrosome,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Centrosome, Cytosol" "HPA002116: AB_1858162" "unprognostic (5.50e-3)" "unprognostic (9.98e-3)" "unprognostic (3.06e-2)" "unprognostic (1.01e-2)" "unprognostic (4.01e-2)" "unprognostic (9.47e-2)" "unprognostic (5.01e-3)" "unprognostic (4.40e-2)" "unprognostic (2.92e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (6.05e-4)" "unprognostic (6.06e-2)" "unprognostic (3.55e-3)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" 57.0 15.6 4.4 114.6 3.8 519.5 23.3 2.9 23.9 27.5 12.0 22.6 21.4 31.3 5.2 26.6 23.4 47.8 23.0 3.2 2.8 13.8 27.4 56.2 76.8 6.1 3.9 73.2 25.8 25.8 7.5 28.9 6.7 17.3 24.7 19.1 16.1 10.3 8.6 50.5 30.7 33.5 6.6 46.1 22.8 8.3 9.5 71.1 11.7 3.8 55.7 171.1 14.6 6.2 32.6 4.8 1.8 2.8 10.1 16.9 7.8 18.8 67.6 4.8 5.7 34.9 8.8 7.3 43.1 20.0 106.5 22.6 1.1 50.4 8.9 46.8 2.2 7.5 19.8 21.1 11.2 10.3 12.8 15.6 7.3 56.4 53.6 5.6 2.9 21.2 17.4 161.3 8.4 1.8 56.2 41.4 1.5 2.1 1.4 151.5 39.4 6.1 14.8 15.1 0.7 0.3 3.6 5.3 16.9 7.0 3.4 11.7 14.8 46.9 6.8 46.0 9.6 48.7 131.4 14.0 16.9 13.1 6.1 7.3 12.6 9.6 19.6 9.3 27.9 7.4 19.4 18.0 14.3 7.8 13.1 10.1 13.6 11.1 5.1 26.2 19.2 14.8 4.4 3.8 2.9 23.9 3.2 2.8 6.1 3.9 6.7 6.6 9.5 6.2 71.8 38.5 76.3 2.0 94.5 774.9 150.2 102.1 384.7 1.1 29.0 42.3 4.6 25.8 53.7 0.0 29.2 8.1 395.5 53.9 1.9 60.0 2.6 605.2 365.9 114.8 11.9 5.2 0.1 26.9 104.8 110.1 111.1 1498.3 255.9 2.3 48.5 13.5 45.7 0.0 0.3 38.6 67.1 125.2 461.8 3.2 6.8 596.6 129.9 8.4 59.1 1.7 14.4 2.0 0.3 30.5 29.5 6.0 331.4 170.2 37.3 3.1 84.3 13.3 6.6 29.0 94.9 2.7 2.2 367.9 745.7 23.1 624.2 14.9 20.9 78.1 TNFRSF13B "CD267, IGAD2, TACI" ENSG00000240505 "TNF receptor superfamily member 13B" O14836 17 16929816-16972118 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 18.9;lymphoid tissue: 33.0;skeletal muscle: 62.9" "Group enriched" "Detected in some" 4 "B-cells: 117.3;Plasma cells: 143.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 41 "memory B-cell: 130.9;naive B-cell: 51.8" "Lineage enriched" "Detected in many" 59 "B-cells: 130.9" "Group enriched" "Detected in some" 9 "Karpas-707: 167.2;RPMI-8226: 106.7;U-266/70: 72.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030453 Uncertain NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "HPA030453: AB_10601700" "unprognostic (3.94e-5)" "unprognostic (1.11e-3)" "unprognostic (4.88e-2)" "unprognostic (4.30e-3)" "unprognostic (1.23e-4)" "unprognostic (2.16e-1)" "unprognostic (1.62e-3)" "unprognostic (1.47e-2)" "unprognostic (1.61e-4)" "unprognostic (2.22e-1)" "unprognostic (9.78e-2)" "unprognostic (1.59e-5)" "unprognostic (1.20e-1)" "unprognostic (4.49e-1)" "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" 0.4 0.1 0.3 8.9 0.4 1.1 0.7 0.0 0.5 0.3 0.0 3.4 4.1 0.1 0.0 1.3 0.4 0.5 5.3 0.1 0.3 0.3 0.3 0.8 17.3 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.9 0.4 2.5 0.3 2.1 0.3 62.9 0.0 18.9 0.1 0.2 33.0 5.2 0.1 0.4 2.0 0.5 0.0 21.6 2.6 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.2 106.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.6 0.0 13.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 130.9 0.0 0.0 0.0 51.8 0.0 0.1 0.5 0.0 0.0 0.0 2.2 2.7 0.3 0.4 0.0 0.5 0.1 0.3 0.4 0.3 0.9 0.2 0.4 1.2 0.0 0.0 0.0 0.0 117.3 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.1 0.0 0.0 0.4 1.1 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.5 32.0 0.0 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 143.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.6 0.0 6.2 0.0 0.0 0.0 TP53BP2 "53BP2, ASPP2, PPP1R13A" ENSG00000143514 "Tumor protein p53 binding protein 2" Q13625 1 223779893-223845954 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 152.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021603, HPA050429" Supported Enhanced "Cell Junctions,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Cell Junctions, Cytosol" "HPA021603: AB_1844384, HPA050429: AB_2681124" "unprognostic (1.29e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-1)" "unprognostic (1.38e-3)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (7.65e-2)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (1.48e-2)" "unprognostic (7.37e-2)" "unprognostic (2.67e-1)" "unprognostic (7.99e-2)" "unprognostic (5.08e-2)" "unprognostic (1.24e-1)" "unprognostic (2.81e-2)" "unprognostic (1.83e-1)" 11.7 8.5 35.3 12.2 37.2 49.8 9.5 34.7 39.4 11.4 35.6 9.9 8.5 12.6 10.0 16.8 10.1 18.4 12.2 33.0 34.4 9.7 14.9 18.4 12.8 34.9 35.8 13.8 12.0 15.8 7.1 8.9 33.2 8.9 9.9 38.0 12.4 8.1 13.0 13.0 10.0 11.1 33.5 9.3 12.4 11.2 37.4 15.8 20.7 11.2 13.1 16.6 11.7 35.8 32.8 16.2 42.9 27.3 15.0 14.5 27.3 20.6 29.3 29.4 25.1 33.6 19.2 0.0 17.5 17.3 21.3 21.9 33.9 12.3 39.3 62.9 33.2 43.1 15.2 11.5 30.3 36.0 28.9 17.5 13.3 27.2 27.7 22.1 17.7 23.6 55.7 31.7 24.8 9.5 27.5 22.2 37.0 19.7 15.6 36.0 44.7 3.7 26.5 20.4 36.9 47.6 22.8 27.9 29.9 27.9 15.8 48.6 20.7 30.0 21.1 32.7 39.2 15.4 17.3 26.4 18.1 23.9 35.0 4.8 1.2 0.8 0.9 1.3 1.2 0.9 1.1 1.8 1.3 0.8 1.1 0.8 1.4 3.3 1.0 0.8 0.8 1.0 35.3 37.2 34.7 39.4 33.0 34.4 34.9 35.8 33.2 33.5 37.4 35.8 18.2 48.1 22.7 76.4 23.7 17.2 41.6 7.2 21.1 8.1 12.6 8.0 20.3 18.6 28.3 7.3 52.1 10.3 24.2 13.0 1.9 20.4 1.1 45.0 42.2 19.1 14.9 54.3 1.7 10.7 5.9 22.6 21.9 152.0 48.8 14.1 8.6 10.7 9.8 0.0 5.3 8.7 14.2 14.1 44.4 2.4 10.5 41.7 8.8 23.4 9.6 10.0 7.2 27.2 29.0 21.4 7.3 8.6 27.4 30.9 6.7 5.5 15.6 45.5 0.0 41.2 26.3 12.3 20.1 21.1 11.6 4.8 38.8 31.4 10.2 40.6 TP53INP1 "DKFZp434M1317, FLJ22139, P53DINP1, SIP, Teap, TP53INP1A, TP53INP1B" ENSG00000164938 "Tumor protein p53 inducible nuclear protein 1" Q96A56 8 94925972-94949378 "Predicted intracellular proteins" "Apoptosis, Autophagy, Transcription, Transcription regulation" "Activator, Antioxidant" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 101.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 175.6;Plasma cells: 233.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 54.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.6" "Cell line enhanced" "Detected in many" "Karpas-707: 79.7;U-266/70: 85.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005856 Uncertain Supported Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA005856: AB_10600832" "unprognostic (1.39e-2)" "unprognostic (4.47e-3)" "unprognostic (7.17e-2)" "unprognostic (2.70e-1)" "unprognostic (5.31e-2)" "prognostic favorable (1.11e-4)" "unprognostic (5.72e-2)" "unprognostic (1.16e-3)" "unprognostic (1.28e-1)" "unprognostic (7.54e-2)" "unprognostic (5.00e-3)" "unprognostic (1.23e-2)" "unprognostic (1.87e-2)" "unprognostic (9.83e-2)" "unprognostic (3.13e-1)" "unprognostic (1.18e-2)" "prognostic favorable (5.45e-5)" 11.2 10.6 6.4 23.1 7.9 42.1 12.7 6.0 7.6 11.8 9.7 16.5 17.2 12.7 12.6 10.9 14.7 10.9 10.9 5.5 6.5 11.5 101.9 25.3 36.0 8.5 6.8 9.0 60.4 10.1 7.1 14.4 7.0 22.5 20.2 17.6 17.9 9.2 9.2 13.1 35.5 12.2 7.0 40.6 25.6 28.6 8.0 29.3 10.2 8.6 41.1 13.3 8.7 8.8 0.5 2.5 24.1 9.3 29.4 27.6 24.8 5.8 13.5 2.6 6.2 2.2 0.6 5.3 12.4 11.2 2.3 4.2 0.0 9.5 5.8 0.3 3.0 3.4 5.3 14.8 19.7 0.0 16.8 45.4 22.2 6.9 2.8 22.4 39.8 2.6 1.8 79.7 12.4 1.7 4.0 1.5 2.3 0.1 0.7 3.4 1.9 29.4 6.3 26.5 3.3 19.5 3.6 2.0 5.2 38.5 11.8 3.3 27.6 4.8 5.8 0.0 0.9 85.4 18.9 2.3 8.4 0.0 0.0 54.6 3.7 11.7 1.4 3.6 1.3 11.5 4.0 2.7 1.4 9.7 0.8 0.6 16.9 5.2 2.3 1.4 6.6 2.5 6.4 7.9 6.0 7.6 5.5 6.5 8.5 6.8 7.0 7.0 8.0 8.8 18.5 35.3 35.7 10.7 70.0 4.6 3.0 17.9 8.0 5.2 27.4 11.6 13.2 75.8 27.9 11.0 27.1 6.1 10.1 27.5 3.9 9.3 17.3 39.9 18.1 14.2 83.9 6.7 0.9 21.3 1.5 11.4 11.2 35.9 4.5 18.8 29.3 175.6 12.5 1.7 2.9 20.9 20.3 44.2 5.6 43.3 7.2 12.6 16.0 16.9 17.7 5.3 3.1 12.1 11.0 18.0 32.2 10.1 233.2 18.1 21.6 9.6 66.4 19.8 6.6 11.0 12.7 18.9 5.6 10.8 6.5 5.7 17.9 26.8 4.8 8.7 TPO TPX ENSG00000115705 "Thyroid peroxidase" P07202 2 1374066-1543711 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 70 "thyroid gland: 1588.2" "Cell type enhanced" "Detected in some" "Adipocytes: 24.5;Early spermatids: 4.2;Endothelial cells: 12.6;Late spermatids: 7.5;Peritubular cells: 3.8" "Cancer enriched" "Detected in some" 364 "thyroid cancer: 188.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory CD4 T-cell: 2.0;T-reg: 1.2" "Lineage enriched" "Detected in single" 20 "T-cells: 2.0" "Group enriched" "Detected in some" 5 "Karpas-707: 9.9;RPMI-8226: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007987, CAB009587" Enhanced "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB009587: , HPA007987: AB_1080270" "unprognostic (1.55e-1)" "unprognostic (1.04e-1)" "unprognostic (2.88e-1)" "unprognostic (1.77e-2)" "unprognostic (3.56e-2)" "unprognostic (9.11e-2)" "unprognostic (2.24e-2)" "unprognostic (1.85e-1)" "unprognostic (1.32e-1)" "unprognostic (1.19e-4)" "unprognostic (2.61e-2)" "unprognostic (3.29e-1)" "unprognostic (5.44e-4)" "unprognostic (1.21e-1)" "unprognostic (3.73e-2)" "unprognostic (4.98e-3)" "unprognostic (7.10e-3)" 13.1 0.3 0.1 0.4 0.0 0.1 11.0 0.0 0.6 0.1 0.0 4.6 0.6 0.6 0.0 2.0 0.7 3.0 11.5 0.1 0.2 0.2 0.6 0.8 1.4 0.2 0.1 0.3 2.3 0.3 0.6 0.0 0.1 0.6 0.9 0.2 3.4 0.0 6.0 1.8 3.8 0.6 0.1 22.8 2.8 1.2 0.2 0.0 1588.2 5.6 0.4 2.1 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.9 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.2 0.1 0.0 0.0 0.6 0.1 0.2 0.2 0.1 0.1 0.1 0.2 0.4 24.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.2 0.0 0.2 12.6 0.0 0.0 2.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.5 0.6 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 1.1 3.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.8 0.3 0.5 0.1 0.0 0.0 0.2 0.1 0.0 0.1 TPTE "CT44, PTEN2" ENSG00000274391 "Transmembrane phosphatase with tensin homology" P56180 21 10521553-10606140 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 201 "testis: 107.2" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 464.7" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.7;K-562: 8.2;Karpas-707: 6.4;MCF7: 4.9;PC-3: 4.8;RPMI-8226: 9.0;SuSa: 7.6;U-266/70: 7.7" "HPA049690, HPA068342" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Endoplasmic reticulum" "HPA049690: AB_2680850, HPA068342: AB_2685976" "unprognostic (3.63e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 6.4 0.0 4.9 0.0 0.0 1.0 0.0 4.8 0.0 0.0 9.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 7.6 0.0 0.0 0.0 1.8 4.1 2.1 0.0 7.7 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 20.6 0.1 0.0 0.1 0.0 0.0 0.7 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.3 13.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.4 0.0 0.0 13.1 0.0 0.0 464.7 69.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 TPTEP2-CSNK1E ENSG00000283900 "TPTEP2-CSNK1E readthrough" 22 38291918-38398522 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.4;B-cells: 1.8;Breast glandular cells: 1.9;Collecting duct cells: 9.2;Endometrial ciliated cells: 2.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 4.0;plasmacytoid DC: 3.5" "Group enriched" "Detected in many" 5 "dendritic cells: 3.5;granulocytes: 4.0" "Cell line enhanced" "Detected in many" "AF22: 5.2;Karpas-707: 9.1;U-266/70: 6.4" HPA026288 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA026288: AB_1847276" 2.9 0.5 0.9 0.7 2.0 2.4 2.8 1.0 1.8 2.5 0.7 1.2 0.3 2.5 0.8 1.0 2.8 0.9 2.1 1.1 2.0 1.1 0.7 1.9 0.5 1.3 1.2 1.0 0.6 2.3 1.5 1.1 1.1 1.2 0.3 2.2 1.6 0.6 1.5 1.7 0.9 0.9 1.2 0.9 0.9 1.3 1.4 0.3 1.8 0.9 1.3 1.3 1.4 2.5 0.7 0.0 5.2 0.5 0.8 1.2 0.7 1.5 4.7 0.7 0.7 0.0 0.4 0.0 0.8 1.2 0.7 0.7 0.5 0.7 0.8 3.5 1.4 0.6 2.6 0.2 0.8 1.4 1.1 0.9 2.2 0.2 0.2 3.5 1.5 0.3 0.5 9.1 0.3 0.2 0.0 0.4 0.6 0.0 0.0 1.2 0.8 2.3 0.7 0.0 0.9 0.3 0.2 0.1 1.9 1.5 0.1 0.5 4.3 0.0 0.7 0.1 0.0 6.4 4.8 1.8 1.7 0.5 0.6 0.4 0.2 4.0 0.0 0.0 0.0 0.7 0.3 0.0 0.3 0.3 0.0 0.0 1.1 0.7 0.0 3.5 0.7 0.1 0.9 2.0 1.0 1.8 1.1 2.0 1.3 1.2 1.1 1.2 1.4 2.5 2.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.0 9.2 0.0 0.0 0.8 0.0 0.0 0.9 0.0 2.0 1.0 0.3 0.0 0.0 0.0 1.3 0.0 0.4 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 TRAF3 "CAP-1, CD40bp, CRAF1, LAP1, RNF118" ENSG00000131323 "TNF receptor associated factor 3" Q13114 14 102777449-102911500 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Immunity, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002933 Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA002933: AB_1080352" "unprognostic (4.06e-2)" "unprognostic (1.75e-2)" "unprognostic (2.08e-2)" "unprognostic (4.49e-3)" "unprognostic (5.25e-2)" "unprognostic (4.17e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (1.31e-1)" "unprognostic (7.24e-2)" "unprognostic (1.16e-1)" "prognostic favorable (2.42e-5)" "unprognostic (1.29e-1)" "unprognostic (2.29e-2)" "unprognostic (1.28e-1)" "unprognostic (1.71e-1)" "unprognostic (3.13e-2)" "unprognostic (2.12e-1)" 6.6 4.2 8.3 18.8 8.7 20.5 4.8 6.3 14.5 3.9 7.6 7.9 7.7 5.8 2.3 6.6 6.8 6.2 6.3 15.6 12.1 5.4 6.4 7.3 20.9 9.8 9.9 3.3 4.5 7.2 8.4 3.9 9.5 5.0 6.3 4.4 4.8 5.7 5.6 6.8 10.7 6.4 8.1 12.0 6.7 10.7 12.8 9.4 6.1 3.3 15.9 8.8 4.7 8.0 25.3 26.4 14.8 9.7 7.5 11.4 23.4 19.1 19.0 19.1 16.7 13.3 36.7 18.6 22.5 19.2 25.8 14.9 20.4 20.4 19.1 50.2 13.9 18.2 11.7 10.3 12.0 21.4 54.5 11.4 13.9 13.1 18.3 10.9 13.9 27.8 18.2 57.4 11.8 23.6 46.2 12.6 8.0 10.7 19.2 25.5 19.8 11.7 16.8 29.3 38.3 13.8 19.8 14.1 13.0 6.6 13.1 24.2 29.9 18.0 14.8 48.0 27.8 42.2 51.7 36.0 20.5 10.8 21.8 3.3 5.1 1.8 2.9 4.0 2.4 10.0 4.2 2.6 3.6 9.5 3.0 2.1 3.8 2.4 2.5 5.9 3.8 5.0 8.3 8.7 6.3 14.5 15.6 12.1 9.8 9.9 9.5 8.1 12.8 8.0 4.2 6.4 8.9 54.5 43.3 12.2 20.4 20.0 18.2 42.6 9.1 6.9 8.0 10.0 13.8 0.0 6.2 5.3 12.8 14.9 3.9 15.8 9.7 20.2 13.5 8.6 17.4 2.1 108.3 17.8 11.7 11.2 8.6 12.2 8.2 3.5 1.4 5.3 12.9 15.2 63.1 15.8 10.2 8.7 29.5 7.6 1.8 20.3 17.8 23.4 18.1 5.4 8.2 63.8 43.6 22.6 5.9 6.4 42.1 28.8 16.9 8.3 19.2 11.0 0.0 12.2 8.4 14.2 33.2 12.7 12.6 3.4 21.9 1.5 11.3 24.9 TRAPPC11 "C4orf41, FLJ12716, foigr, gry" ENSG00000168538 "Trafficking protein particle complex 11" Q7Z392 4 183659267-183713594 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038173 Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Vesicles "HPA038173: " "unprognostic (2.24e-1)" "unprognostic (6.03e-2)" "unprognostic (9.92e-3)" "unprognostic (1.31e-2)" "unprognostic (1.08e-1)" "unprognostic (1.00e-1)" "unprognostic (9.14e-2)" "unprognostic (6.24e-2)" "unprognostic (2.63e-1)" "unprognostic (6.50e-2)" "unprognostic (5.78e-2)" "unprognostic (2.17e-1)" "prognostic favorable (2.66e-5)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (2.25e-2)" "unprognostic (3.92e-2)" 12.1 15.9 4.3 13.4 5.5 11.4 15.5 8.3 6.4 12.4 15.4 13.2 11.0 14.1 11.8 13.8 12.4 11.0 12.4 5.5 4.8 14.8 16.9 13.6 14.9 3.4 4.1 20.8 14.2 19.1 6.8 13.8 3.7 14.1 15.0 13.8 14.8 12.1 15.1 12.1 11.7 15.7 4.4 14.2 13.5 16.0 4.9 17.8 14.8 18.7 17.6 13.6 8.0 6.0 15.1 14.4 23.2 23.1 28.5 31.3 17.6 21.6 21.7 17.8 16.2 9.0 19.1 20.7 6.0 21.8 13.9 10.8 21.2 20.5 20.4 23.1 9.3 26.0 12.0 12.8 26.2 28.3 24.8 24.2 21.5 17.8 20.6 23.2 26.5 23.9 21.1 41.8 22.5 10.8 34.1 13.8 8.7 10.2 10.7 23.4 13.8 15.8 22.8 15.3 15.6 20.7 21.1 21.6 21.4 20.5 16.6 31.0 26.7 10.1 11.9 9.7 12.4 21.8 12.7 12.4 20.6 18.7 18.0 3.8 12.9 8.2 5.7 14.9 7.6 4.7 6.2 6.1 12.8 3.4 5.7 5.9 3.7 10.0 25.6 3.3 5.4 7.6 4.3 5.5 8.3 6.4 5.5 4.8 3.4 4.1 3.7 4.4 4.9 6.0 9.5 3.2 14.5 33.0 12.3 4.5 3.1 7.4 9.1 11.0 5.7 6.2 14.8 8.6 9.1 7.3 8.4 7.9 10.0 9.8 3.9 7.4 57.7 8.2 13.3 9.1 13.1 12.0 47.5 9.3 8.4 12.0 12.2 8.0 7.6 18.7 9.3 8.5 11.6 8.4 47.4 7.2 0.0 16.0 6.8 7.3 13.4 16.1 3.6 30.0 19.5 6.4 11.3 37.2 35.2 9.0 7.1 11.3 10.6 5.5 11.7 4.6 12.9 13.6 0.0 9.9 8.6 7.7 14.9 10.4 6.1 7.0 9.4 12.4 7.9 5.9 TRAPPC2 "hYP38334, MIP-2A, SEDL, SEDT, TRS20, ZNF547L" ENSG00000196459 "Trafficking protein particle complex 2" P0DI81 X 13712244-13734635 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB004665, HPA063308" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum, Vesicles" Nucleoplasm "CAB004665: AB_425678, HPA063308: AB_2684982" "unprognostic (1.97e-1)" "prognostic favorable (8.09e-4)" "unprognostic (2.13e-1)" "unprognostic (4.18e-1)" "unprognostic (2.11e-1)" "unprognostic (2.70e-2)" "unprognostic (1.04e-2)" "unprognostic (2.08e-3)" "unprognostic (1.76e-2)" "prognostic favorable (6.35e-4)" "unprognostic (3.50e-2)" "unprognostic (8.24e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (2.36e-1)" "prognostic favorable (7.89e-5)" 6.0 5.7 12.5 6.7 13.4 7.6 6.8 13.1 14.2 10.0 10.7 10.9 6.0 11.0 6.3 8.4 9.4 5.5 5.3 13.3 13.9 7.4 8.2 7.5 12.7 12.1 11.2 11.2 9.2 5.2 7.7 5.3 12.5 8.3 6.4 10.2 7.3 5.1 4.4 7.4 9.6 8.8 10.2 10.3 9.7 3.2 14.9 9.0 7.8 2.7 11.8 8.9 9.9 11.8 9.1 6.2 10.5 26.1 8.0 5.9 3.7 8.5 7.8 6.7 6.9 5.8 11.0 14.8 13.2 6.9 8.8 11.0 13.8 12.4 8.6 15.3 20.4 11.3 16.0 5.2 6.4 15.9 20.8 8.0 7.0 14.7 17.1 13.4 6.3 11.1 15.0 26.3 7.3 16.0 16.0 21.7 10.6 7.2 11.4 15.3 14.3 14.6 10.8 5.5 10.6 13.6 14.5 12.1 11.0 16.3 13.5 10.6 7.9 6.7 6.2 11.4 5.5 13.3 13.8 19.6 6.0 10.5 6.4 19.3 6.0 11.0 18.1 8.4 18.2 13.2 14.3 17.8 5.5 12.8 11.8 16.6 11.7 22.9 6.9 13.0 18.7 11.1 12.5 13.4 13.1 14.2 13.3 13.9 12.1 11.2 12.5 10.2 14.9 11.8 8.9 9.6 6.5 7.8 22.0 15.2 10.0 14.8 9.6 16.5 16.5 13.6 11.0 15.7 14.6 9.2 12.5 14.1 49.8 14.6 21.5 10.0 17.7 17.3 11.0 9.3 12.1 12.4 20.7 13.4 19.9 11.5 14.8 21.2 9.5 16.9 16.8 12.2 11.6 20.2 20.2 14.0 8.2 12.9 14.4 6.1 12.8 13.6 8.8 10.3 12.0 8.8 44.3 31.7 17.3 15.7 18.6 11.3 17.6 9.8 15.4 23.8 8.5 14.5 6.6 8.6 18.5 4.3 4.0 11.3 17.6 17.9 28.8 16.6 13.2 12.5 TRAPPC3L "bA259P20.2, BET3L, FLJ11180" ENSG00000173626 "Trafficking protein particle complex 3 like" Q5T215 6 116494989-116545684 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.1" "Cell type enhanced" "Detected in some" "Adipocytes: 1.6;Early spermatids: 1.8;Endothelial cells: 1.5;Hepatic stellate cells: 6.1;Kupffer cells: 4.2;Macrophages: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA060912 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus, Vesicles" "HPA060912: " "unprognostic (1.34e-1)" "unprognostic (7.24e-2)" "unprognostic (1.93e-2)" "unprognostic (2.91e-1)" "unprognostic (5.25e-2)" "unprognostic (1.15e-2)" "unprognostic (8.98e-2)" "unprognostic (9.09e-4)" "unprognostic (8.41e-2)" "unprognostic (3.23e-2)" "unprognostic (1.96e-1)" "unprognostic (2.91e-3)" "unprognostic (2.59e-3)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "unprognostic (8.11e-2)" "unprognostic (7.47e-3)" 0.7 0.7 1.6 0.8 1.7 3.7 1.0 8.1 5.0 0.4 0.3 0.7 1.0 1.2 1.8 0.7 0.5 1.1 0.9 2.3 0.0 0.7 1.4 1.2 1.7 0.6 0.1 1.0 0.7 3.0 0.0 3.9 1.6 0.7 0.5 4.2 1.2 0.7 1.2 2.3 1.0 0.4 0.1 4.7 1.1 1.5 0.7 0.5 1.8 0.2 0.6 0.5 0.0 3.9 0.8 0.4 1.0 1.5 0.3 1.0 1.1 0.5 0.5 0.4 0.5 0.5 0.7 1.3 0.6 0.2 0.8 1.0 0.3 0.6 0.5 0.6 0.6 1.4 1.9 0.6 0.5 0.9 0.6 0.4 0.3 0.2 0.3 1.5 0.8 1.0 0.8 6.6 0.3 1.5 0.9 1.0 0.9 0.3 0.6 0.8 0.7 2.2 0.7 1.3 1.0 0.7 0.8 0.4 0.5 1.2 0.7 0.8 1.0 1.2 0.9 1.2 0.6 1.2 0.8 0.8 0.8 0.9 0.7 0.6 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.9 0.1 0.2 0.3 0.1 2.8 1.6 1.7 8.1 5.0 2.3 0.0 0.6 0.1 1.6 0.1 0.7 3.9 1.6 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 1.5 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.4 6.1 0.1 1.1 0.0 0.1 0.0 0.0 4.2 0.0 0.4 0.3 3.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.2 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.0 TRBV12-5 "TCRBV12S5, TCRBV8S3, TRBV125" ENSG00000275158 "T cell receptor beta variable 12-5" A0A1B0GX78 7 142580917-142581427 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 74 "lymphoid tissue: 48.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "memory CD4 T-cell: 4.8;naive CD4 T-cell: 8.3;naive CD8 T-cell: 8.7;T-reg: 9.8" "Lineage enriched" "Detected in single" 99 "T-cells: 9.8" "Cell line enhanced" "Detected in single" "Karpas-707: 1.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (5.12e-2)" "unprognostic (7.81e-2)" "unprognostic (2.53e-1)" "unprognostic (2.37e-3)" "unprognostic (2.74e-2)" "unprognostic (1.18e-1)" "unprognostic (1.55e-7)" "unprognostic (6.99e-2)" "unprognostic (2.00e-1)" "unprognostic (8.36e-2)" 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 48.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 1.0 0.0 0.0 8.3 8.7 0.0 0.0 0.0 0.0 9.8 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 TRGV2 "TCRGV2, VIS2" ENSG00000233306 "T cell receptor gamma variable 2" A0A075B6R0 7 38362864-38363518 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 6.6" "Cell type enriched" "Detected in some" 5 "T-cells: 19.2" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 147.8" "Lineage enriched" "Detected in many" 22 "T-cells: 147.8" "Cell line enriched" "Detected in some" 4 "Karpas-707: 17.4" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.51e-3)" "unprognostic (8.88e-5)" "unprognostic (1.77e-1)" "unprognostic (1.01e-2)" "unprognostic (1.72e-1)" "unprognostic (4.31e-4)" "unprognostic (1.50e-3)" "unprognostic (1.13e-1)" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (7.48e-2)" "unprognostic (3.02e-1)" "unprognostic (4.21e-5)" "unprognostic (1.43e-2)" "unprognostic (1.96e-1)" "unprognostic (1.25e-1)" "unprognostic (4.87e-3)" 0.4 0.6 0.0 1.6 0.0 0.9 0.1 0.0 0.2 0.2 0.2 0.8 0.8 0.3 0.1 0.1 0.3 1.0 0.2 0.0 0.0 0.1 0.3 0.9 5.0 0.7 0.4 0.0 0.1 0.0 0.1 0.0 0.2 1.2 0.6 0.1 0.9 0.1 0.1 0.2 1.4 0.4 0.1 6.6 0.7 0.3 0.4 4.8 0.3 0.0 0.7 0.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 2.4 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 1.0 17.4 0.0 0.0 0.5 0.8 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.7 1.7 0.1 0.0 3.8 0.0 0.2 0.4 0.0 59.4 0.2 58.4 0.1 29.7 147.8 1.4 0.2 7.0 54.9 0.9 6.8 0.1 1.5 0.6 22.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.4 0.2 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 TRGV3 "TCRGV3, V1S3" ENSG00000211699 "T cell receptor gamma variable 3" P03979 7 38358512-38359162 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 12.4" "Cell type enhanced" "Detected in some" "dendritic cells: 1.8;Plasma cells: 2.6;T-cells: 5.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "gdT-cell: 59.0" "Lineage enriched" "Detected in many" 5 "T-cells: 59.0" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;JURKAT: 12.1;Karpas-707: 28.9;U-266/84: 5.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.87e-2)" "unprognostic (1.63e-3)" "unprognostic (4.58e-2)" "unprognostic (6.48e-3)" "unprognostic (4.66e-2)" "unprognostic (1.57e-3)" "unprognostic (2.28e-1)" "unprognostic (1.72e-2)" "unprognostic (1.49e-1)" "unprognostic (4.46e-2)" "unprognostic (4.75e-2)" "unprognostic (1.46e-1)" "unprognostic (5.26e-3)" "unprognostic (2.28e-1)" "unprognostic (3.46e-2)" "unprognostic (3.71e-2)" "unprognostic (3.42e-2)" 0.6 0.3 0.1 1.3 0.1 2.8 0.5 0.1 0.2 0.7 0.1 1.8 1.0 0.6 0.0 0.5 0.6 3.9 0.3 0.1 0.3 0.4 0.7 1.4 12.4 0.7 1.3 0.1 0.2 0.3 0.2 1.0 0.4 1.3 1.9 0.0 1.1 0.4 0.1 0.3 3.1 0.7 0.5 7.6 1.3 0.5 0.5 9.3 0.4 0.0 8.9 2.0 0.3 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 7.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 3.8 12.1 0.7 28.9 0.0 0.2 0.0 1.4 0.2 0.0 0.0 1.5 1.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 3.1 0.8 0.0 0.0 0.0 0.1 3.0 5.9 0.4 0.1 1.6 0.0 0.1 1.6 0.0 59.0 0.7 50.1 3.4 11.0 34.0 5.7 1.8 9.4 27.6 0.1 11.4 2.2 11.1 6.3 8.0 0.1 0.1 0.1 0.2 0.1 0.3 0.7 1.3 0.4 0.5 0.5 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 TRGV4 "TCRGV4, V1S4" ENSG00000211698 "T cell receptor gamma variable 4" A0A0C4DH28 7 38353715-38354517 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 11.1" "Cell type enhanced" "Detected in some" "dendritic cells: 2.7;Plasma cells: 2.1;T-cells: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "gdT-cell: 97.8" "Lineage enriched" "Detected in many" 15 "T-cells: 97.8" "Cell line enriched" "Detected in some" 4 "Karpas-707: 72.0" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (7.44e-3)" "unprognostic (7.26e-3)" "unprognostic (5.77e-2)" "unprognostic (1.90e-2)" "unprognostic (3.58e-1)" "unprognostic (6.75e-3)" "unprognostic (9.66e-2)" "unprognostic (8.83e-3)" "unprognostic (1.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.42e-2)" "unprognostic (1.58e-1)" "unprognostic (2.59e-3)" "unprognostic (2.24e-1)" "unprognostic (1.14e-1)" "unprognostic (2.47e-2)" "unprognostic (3.71e-3)" 0.4 0.4 0.2 0.4 0.2 3.0 0.4 0.3 0.2 0.3 0.8 1.6 0.4 0.4 0.2 0.4 0.5 2.2 0.2 0.2 0.2 0.4 1.4 1.7 11.1 0.8 1.2 0.1 0.1 0.1 0.2 0.4 0.5 1.9 1.4 0.0 0.9 0.3 0.1 0.5 3.5 0.3 0.4 9.0 1.6 0.7 0.9 7.1 0.4 0.0 4.9 0.8 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 13.9 0.1 8.3 0.0 0.0 0.0 4.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 8.3 4.6 72.0 0.1 0.2 0.0 16.8 0.4 0.0 0.1 0.6 0.9 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.2 0.0 0.0 0.0 2.7 1.9 0.0 1.1 14.5 0.0 0.2 1.5 0.1 97.8 0.3 30.1 1.0 4.4 26.8 1.7 0.6 2.0 23.8 0.6 6.5 0.1 5.8 1.4 7.2 0.2 0.2 0.3 0.2 0.2 0.2 0.8 1.2 0.5 0.4 0.9 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 TRGV5 "TCRGV5, V1S5" ENSG00000211697 "T cell receptor gamma variable 5" A0A0B4J1U4 7 38349355-38350022 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.0" "Cell type enhanced" "Detected in some" "dendritic cells: 2.4;Hepatic stellate cells: 1.8;Hofbauer cells: 2.9;Kupffer cells: 7.2;Plasma cells: 2.5;T-cells: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HDLM-2: 6.9;JURKAT: 11.1;Karpas-707: 15.2;NB-4: 4.7;U-266/84: 4.9;U-87 MG: 6.8;U-937: 6.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.17e-2)" "unprognostic (1.21e-2)" "unprognostic (6.61e-2)" "unprognostic (2.62e-4)" "unprognostic (5.91e-3)" "unprognostic (1.66e-2)" "unprognostic (3.18e-2)" "unprognostic (3.00e-1)" "unprognostic (3.42e-2)" "unprognostic (2.88e-1)" "unprognostic (2.39e-2)" "unprognostic (1.06e-1)" "unprognostic (7.73e-6)" "unprognostic (1.62e-1)" "unprognostic (2.35e-1)" "unprognostic (1.69e-1)" "unprognostic (3.77e-2)" 0.4 0.4 0.0 0.9 0.0 2.3 0.4 0.0 0.0 0.5 0.1 1.2 0.0 0.2 0.1 0.3 0.2 1.9 0.3 0.0 0.0 0.4 1.1 1.2 3.7 0.4 0.7 0.2 0.0 0.0 0.1 0.6 0.3 0.8 1.0 0.0 0.6 0.1 0.2 0.3 1.0 0.6 0.1 3.6 0.8 0.2 0.3 6.0 0.3 0.3 4.7 1.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.3 0.4 1.4 0.0 0.0 0.0 0.0 6.9 0.8 1.9 0.0 0.0 0.0 2.1 1.3 0.2 0.0 0.0 0.0 0.0 0.5 11.1 0.2 15.2 0.1 0.3 0.0 4.7 0.0 0.0 0.0 0.4 0.7 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.8 0.0 0.4 0.1 0.1 0.0 0.0 4.9 0.4 6.8 6.9 0.0 0.0 5.1 0.6 24.5 1.7 20.1 0.7 2.9 22.4 5.6 0.7 1.4 9.5 0.3 8.2 0.2 6.9 3.7 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 1.8 0.0 2.9 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.0 0.0 0.1 6.0 0.0 0.0 0.0 TRIM39 RNF23 ENSG00000204599 "Tripartite motif containing 39" Q9HCM9 6 30326479-30343729 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051120, HPA059496" Uncertain Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA051120: AB_2681348, HPA059496: AB_2684040" "unprognostic (2.90e-1)" "unprognostic (1.61e-2)" "unprognostic (2.79e-2)" "unprognostic (2.86e-2)" "unprognostic (6.38e-2)" "unprognostic (4.55e-2)" "unprognostic (1.46e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-1)" "unprognostic (9.44e-2)" "prognostic favorable (2.50e-4)" "unprognostic (1.30e-2)" "unprognostic (4.69e-2)" "unprognostic (6.35e-3)" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (2.39e-3)" 10.0 8.7 0.8 1.7 1.0 3.1 10.2 1.3 1.1 11.4 1.5 13.6 1.6 12.1 2.2 13.1 11.7 1.3 8.7 0.9 0.9 9.8 11.6 9.7 1.6 1.3 1.0 11.5 12.2 2.1 14.8 1.6 1.0 10.8 1.5 1.5 10.2 2.0 14.3 9.3 11.9 1.8 0.8 14.3 11.0 20.7 1.1 1.7 11.6 1.4 2.1 12.9 9.5 1.1 3.2 0.1 2.6 4.8 1.2 1.2 2.7 1.4 1.8 2.1 1.9 3.8 0.4 4.1 2.8 2.7 1.3 1.0 3.1 2.2 2.2 3.2 3.4 3.2 0.5 1.4 2.7 4.8 3.5 1.4 1.8 2.7 2.9 3.2 1.3 3.4 4.9 3.2 2.7 2.9 1.0 1.0 3.6 1.3 2.2 2.2 0.5 3.1 2.2 3.0 5.7 2.8 1.1 2.3 2.8 2.5 3.1 1.2 1.2 2.3 1.8 2.8 4.9 5.7 7.6 4.2 1.3 1.7 3.6 1.0 0.9 4.1 2.7 1.3 2.4 1.8 1.9 2.0 0.9 1.6 2.2 2.2 4.5 2.6 1.4 0.7 1.7 1.4 0.8 1.0 1.3 1.1 0.9 0.9 1.3 1.0 1.0 0.8 1.1 1.1 5.9 3.2 7.2 0.7 14.2 3.7 5.6 2.6 6.8 6.0 7.5 5.2 5.6 2.8 3.5 1.8 6.2 4.7 11.9 5.5 7.9 4.6 4.6 11.2 4.1 4.8 5.4 3.6 0.9 6.1 5.7 4.1 15.3 13.1 5.7 4.2 5.7 3.7 3.3 3.3 1.1 7.3 4.1 7.2 5.0 7.8 2.8 7.3 3.6 1.0 4.3 6.9 8.2 0.5 0.9 6.8 10.0 4.5 10.9 3.7 7.5 4.0 7.2 7.6 0.0 3.8 5.8 19.1 10.0 5.3 4.1 10.0 15.3 3.5 4.4 5.3 TRPC3 ENSG00000138741 "Transient receptor potential cation channel subfamily C member 3" Q13507 4 121874481-121952060 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.4;pituitary gland: 7.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 18.1;Inhibitory neurons: 82.7;Oligodendrocyte precursor cells: 33.7;Rod photoreceptor cells: 32.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 2.3;Karpas-707: 2.6;U-2 OS: 1.5;U-251 MG: 1.5" "Region enhanced" "Detected in all" "cerebellum: 57.8" "Low region specificity" "Detected in many" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (2.39e-1)" "unprognostic (3.12e-2)" "unprognostic (5.57e-2)" "unprognostic (1.93e-2)" "unprognostic (7.12e-3)" "unprognostic (9.80e-2)" "unprognostic (4.80e-3)" "unprognostic (2.38e-1)" "unprognostic (3.26e-1)" "unprognostic (1.06e-1)" "unprognostic (4.33e-3)" "unprognostic (2.67e-3)" "unprognostic (1.39e-1)" "unprognostic (2.23e-1)" "unprognostic (8.42e-3)" 0.3 0.0 2.3 0.1 4.0 0.0 0.2 4.6 5.8 0.8 0.1 0.2 0.1 0.4 0.2 0.0 0.5 0.8 0.2 0.8 3.2 0.1 0.1 0.9 0.1 10.4 2.8 0.1 0.0 0.2 7.4 1.1 2.2 0.2 0.1 3.9 0.1 0.6 0.4 0.1 0.5 2.6 1.6 0.2 0.2 0.4 4.6 0.0 0.1 0.2 0.0 1.7 0.7 1.7 0.0 0.0 0.8 0.1 0.1 0.1 0.0 0.4 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.4 0.0 0.1 0.0 1.3 2.3 0.2 0.0 0.1 0.7 0.3 0.2 0.0 0.0 0.0 1.1 0.0 0.1 0.0 2.6 0.5 0.1 0.8 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.1 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.1 1.2 1.5 0.1 1.5 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.3 4.0 4.6 5.8 0.8 3.2 10.4 2.8 2.2 1.6 4.6 1.7 0.5 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.8 0.0 0.0 0.0 8.4 0.0 0.5 0.0 0.0 0.0 2.3 0.0 0.3 0.2 0.0 0.0 18.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 82.7 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.1 4.6 0.0 33.7 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 32.0 0.0 0.3 1.4 0.5 0.8 0.0 0.0 0.0 0.5 0.5 0.0 0.1 TRRAP "PAF400, TR-AP, Tra1" ENSG00000196367 "Transformation/transcription domain associated protein" Q9Y4A5 7 98877933-99050831 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Autism spectrum disorder, Cancer-related genes, Deafness, Disease variant, Mental retardation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054376 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Golgi apparatus" "HPA054376: AB_2682467" "unprognostic (2.10e-1)" "unprognostic (7.79e-2)" "unprognostic (2.21e-1)" "unprognostic (4.35e-2)" "unprognostic (2.02e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.77e-4)" "unprognostic (1.40e-2)" "unprognostic (2.39e-2)" "unprognostic (3.99e-2)" "unprognostic (9.45e-2)" "unprognostic (7.02e-2)" "unprognostic (2.21e-3)" "unprognostic (1.59e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (2.96e-1)" 6.0 8.1 3.4 7.4 3.5 11.1 6.2 10.3 3.7 8.3 5.9 7.7 5.3 8.6 3.5 6.8 8.4 4.9 6.8 3.1 2.6 6.2 6.7 7.0 9.3 1.4 2.2 10.9 8.3 10.3 14.0 6.1 1.9 7.1 5.0 7.5 7.1 5.2 7.6 11.2 8.4 6.2 0.6 8.5 7.1 11.0 2.8 15.8 8.8 7.3 8.7 7.3 7.0 5.0 24.0 27.2 27.7 23.4 12.9 13.8 13.7 10.3 13.6 15.8 15.1 21.2 10.3 32.8 15.9 19.1 30.3 12.2 29.1 14.0 17.7 19.2 28.3 20.2 20.3 11.7 9.4 36.9 14.3 12.6 8.0 25.8 21.7 10.9 20.5 29.2 35.4 59.8 14.8 44.0 45.0 13.5 21.1 14.1 16.6 32.7 16.0 25.2 7.7 26.6 21.6 27.1 26.1 16.6 8.4 22.7 8.5 15.7 22.0 21.1 30.6 28.3 24.2 24.7 30.2 47.8 14.9 18.3 21.3 2.8 0.3 0.2 0.5 0.2 0.9 0.6 0.8 0.4 0.3 0.8 0.6 0.6 1.0 0.5 0.3 1.0 0.7 0.1 3.4 3.5 10.3 3.7 3.1 2.6 1.4 2.2 1.9 0.6 2.8 5.0 12.8 16.0 14.2 30.3 16.4 15.8 4.2 8.2 13.1 15.2 13.7 10.0 10.9 5.7 9.4 14.7 27.1 8.9 15.0 7.9 0.0 7.7 3.6 16.6 20.1 11.1 12.6 12.4 43.7 6.5 5.2 11.1 11.2 24.1 5.7 26.5 8.6 11.0 8.0 21.9 45.5 10.4 8.2 10.4 7.4 5.4 8.7 12.3 8.8 29.0 9.8 6.1 6.2 36.7 42.4 8.3 5.8 8.6 25.3 7.6 6.2 5.2 8.3 9.2 0.0 12.8 12.4 14.8 8.4 18.5 21.3 10.9 17.1 12.1 10.1 7.5 TSPAN4 "NAG-2, TETRASPAN, TM4SF7, TSPAN-4" ENSG00000214063 "Tetraspanin 4" O14817 11 842812-867116 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 194.2;Fibroblasts: 168.7;Hofbauer cells: 240.6;Leydig cells: 172.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 146.4;intermediate monocyte: 143.5;myeloid DC: 101.2;NK-cell: 95.6;non-classical monocyte: 39.9" "Group enriched" "Detected in all" 10 "dendritic cells: 101.2;monocytes: 146.4;NK-cells: 95.6" "Low cell line specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 142.8" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (6.39e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.88e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (1.24e-1)" "unprognostic (6.13e-2)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (9.49e-2)" "unprognostic (2.41e-2)" "unprognostic (1.29e-2)" "unprognostic (2.61e-2)" "unprognostic (2.41e-2)" "unprognostic (1.18e-1)" 129.1 37.1 15.8 29.6 14.7 11.8 102.0 17.9 18.7 90.9 44.1 60.3 13.7 84.2 9.2 26.1 85.8 54.1 57.6 15.6 17.4 60.8 37.6 101.4 46.3 17.1 16.7 91.3 32.5 17.6 24.2 61.6 15.6 52.9 10.5 2.5 34.2 33.7 25.7 56.3 43.3 27.5 15.5 85.0 37.0 16.8 18.2 13.2 79.9 22.9 12.7 66.8 71.8 12.9 30.7 238.7 40.8 73.6 61.2 121.4 27.5 153.0 182.5 118.4 81.3 49.5 37.5 2.3 60.4 221.3 68.2 11.3 14.5 145.6 22.2 20.4 17.4 32.5 75.7 71.6 201.4 10.4 38.9 211.5 26.1 42.8 129.0 116.1 78.5 12.5 13.5 184.5 115.8 64.6 7.0 13.0 52.3 39.2 172.7 24.2 29.1 55.4 138.3 2.0 48.0 28.6 75.8 83.6 162.1 17.4 118.5 7.7 116.0 134.2 53.4 27.3 52.2 10.2 1.5 4.5 138.5 11.1 121.8 0.1 146.4 0.1 7.4 143.5 4.6 6.9 3.7 7.2 101.2 5.4 6.2 11.7 3.4 95.6 39.9 7.0 3.6 65.2 15.8 14.7 17.9 18.7 15.6 17.4 17.1 16.7 15.6 15.5 18.2 12.9 194.2 105.8 68.5 6.5 5.6 47.5 22.2 78.8 13.6 9.5 19.4 38.6 9.5 74.4 24.6 31.3 4.2 39.5 8.1 1.7 7.9 82.6 2.1 5.9 43.2 117.3 0.0 12.0 0.6 16.7 31.9 168.7 5.6 10.8 37.2 62.8 97.5 28.2 240.6 13.5 2.9 2.6 4.1 109.9 71.5 7.3 172.7 70.3 147.7 11.2 19.2 43.8 8.2 2.5 0.3 61.3 0.3 95.2 9.3 15.7 0.3 34.7 5.8 6.7 59.2 23.9 67.5 4.7 31.5 6.1 32.8 16.8 10.2 44.7 1.1 6.1 TSTD3 ENSG00000279170 "Thiosulfate sulfurtransferase like domain containing 3" H0UI37 6 99520976-99589899 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 81.9;Excitatory neurons: 41.7;Inhibitory neurons: 49.4;Oligodendrocyte precursor cells: 62.8;Oligodendrocytes: 93.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 6.1" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.43e-1)" "unprognostic (2.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.70e-2)" "unprognostic (6.01e-2)" "unprognostic (9.22e-2)" "unprognostic (5.74e-2)" "unprognostic (6.38e-2)" "unprognostic (9.44e-3)" "unprognostic (4.70e-2)" "unprognostic (3.56e-2)" "unprognostic (7.83e-3)" "unprognostic (3.13e-1)" "unprognostic (2.00e-1)" "unprognostic (3.62e-2)" "unprognostic (2.88e-3)" 3.9 1.0 0.6 0.8 1.2 1.3 1.2 3.5 2.2 0.5 0.8 1.0 1.2 0.5 1.0 0.4 1.2 1.6 1.5 0.7 0.9 1.4 0.7 1.0 0.6 1.3 0.8 0.6 1.1 3.2 0.7 1.1 2.6 0.9 1.2 1.1 0.8 2.0 1.1 0.7 0.5 0.7 0.6 1.4 0.4 1.1 0.7 2.0 1.1 0.4 0.7 2.5 0.8 1.5 0.8 2.5 4.7 2.2 1.0 0.6 0.8 0.6 0.5 0.9 2.2 0.2 1.1 0.9 3.3 0.8 0.7 1.0 0.5 0.7 0.4 0.2 4.0 1.5 3.1 1.1 1.4 1.3 2.2 0.3 3.5 3.2 1.0 1.2 1.3 6.1 1.4 1.4 0.5 1.2 0.8 3.8 1.3 0.0 1.0 1.9 3.4 0.5 1.1 0.3 1.0 0.7 1.2 4.7 1.6 0.2 0.7 1.1 0.9 0.5 0.6 0.5 0.4 1.8 2.7 0.8 1.6 1.6 0.4 1.1 0.4 0.1 0.6 0.8 0.4 0.3 0.2 1.6 0.3 0.4 1.1 1.4 0.1 0.5 0.1 0.1 0.6 1.2 3.5 2.2 0.7 0.9 1.3 0.8 1.1 0.7 1.1 2.5 1.5 3.2 5.4 81.9 5.5 1.9 4.1 5.8 4.6 1.4 6.2 5.2 0.0 11.5 6.4 12.9 0.0 0.0 2.2 5.2 23.5 4.5 0.3 5.4 4.0 4.1 3.6 9.9 41.7 7.8 0.0 3.6 5.6 3.1 1.3 1.9 7.9 3.4 0.0 0.0 49.4 5.6 14.2 3.2 0.8 1.0 6.5 1.7 5.4 26.2 2.5 7.9 2.1 62.8 93.3 6.5 4.2 9.8 1.4 4.8 5.7 16.3 6.7 2.8 13.1 3.8 4.7 0.8 1.9 4.9 2.0 0.0 3.5 3.0 5.7 4.2 TTC32 ENSG00000183891 "Tetratricopeptide repeat domain 32" Q5I0X7 2 19896631-19901983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036024 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria Nucleoplasm "HPA036024: AB_10673493" "unprognostic (2.77e-3)" "unprognostic (5.44e-2)" "unprognostic (8.85e-2)" "unprognostic (8.80e-3)" "unprognostic (1.08e-1)" "unprognostic (2.62e-1)" "unprognostic (5.25e-2)" "prognostic favorable (9.44e-4)" "unprognostic (4.46e-2)" "unprognostic (1.48e-2)" "unprognostic (4.92e-3)" "unprognostic (6.22e-2)" "prognostic unfavorable (5.45e-6)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-2)" "unprognostic (2.27e-2)" 11.8 8.8 8.7 12.3 10.5 34.7 16.6 13.6 17.2 12.3 8.6 11.7 12.2 13.9 26.0 7.4 11.9 6.7 7.1 8.8 9.1 11.4 12.3 10.0 15.5 10.6 10.0 16.5 8.6 8.2 11.3 8.5 11.3 16.0 10.2 33.0 11.1 9.3 22.5 13.8 13.1 8.0 9.5 15.6 11.4 12.5 9.7 19.7 12.4 7.7 10.1 11.3 11.2 14.2 22.5 14.4 12.8 9.6 5.6 12.3 2.7 4.8 8.0 7.7 5.0 7.3 25.6 14.5 2.7 5.1 9.6 14.6 5.6 15.4 4.9 21.3 23.3 14.8 20.4 12.8 12.1 14.2 25.5 11.7 9.6 8.6 20.4 6.5 7.5 23.3 27.1 28.5 6.4 6.8 10.7 21.7 9.6 8.4 24.1 12.6 8.5 24.1 21.6 8.6 20.6 19.1 16.1 8.5 18.2 14.1 11.9 5.5 5.6 11.6 12.4 11.5 6.6 29.8 27.3 24.0 17.9 13.9 6.7 9.2 7.6 23.1 7.3 5.7 8.7 12.2 11.6 7.8 7.2 11.9 15.8 12.2 28.0 6.7 6.9 5.0 15.6 4.9 8.7 10.5 13.6 17.2 8.8 9.1 10.6 10.0 11.3 9.5 9.7 14.2 23.2 9.6 14.4 8.5 24.7 18.9 33.4 36.0 34.7 66.9 27.4 39.0 15.8 15.7 26.4 12.9 14.6 14.6 13.7 10.0 45.0 12.2 27.2 25.8 6.1 16.2 28.3 34.0 7.1 24.8 8.7 19.6 14.8 13.2 8.8 7.2 7.5 24.1 9.1 42.1 8.6 19.9 32.6 8.8 8.9 7.2 19.9 17.4 7.2 5.6 14.6 67.8 11.3 9.5 22.0 14.6 12.9 9.8 12.3 15.8 13.7 28.5 48.7 39.2 13.1 21.1 21.3 113.2 38.7 22.4 26.1 9.6 21.6 9.0 11.7 26.7 UBALD2 "FAM100B, MGC29814" ENSG00000185262 "UBA like domain containing 2" Q8IYN6 17 76265348-76271298 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 229.1" "Cell type enhanced" "Detected in all" "Urothelial cells: 205.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 7.8;neutrophil: 29.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 29.2" "Cell line enhanced" "Detected in all" "HDLM-2: 324.7;Karpas-707: 401.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023046 Uncertain NA Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA023046: AB_1848359" "unprognostic (1.33e-1)" "unprognostic (2.04e-3)" "unprognostic (3.14e-1)" "unprognostic (3.06e-1)" "unprognostic (9.21e-2)" "unprognostic (1.74e-1)" "unprognostic (3.22e-3)" "unprognostic (5.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-1)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (4.80e-2)" "unprognostic (3.78e-2)" "unprognostic (9.24e-2)" "unprognostic (3.45e-3)" "unprognostic (1.45e-3)" 43.9 19.4 36.1 54.4 38.0 229.1 43.6 36.5 48.8 33.1 32.4 53.6 80.0 24.5 8.0 97.9 29.4 14.8 44.5 32.5 53.6 39.1 35.2 72.0 45.0 68.4 42.9 17.7 43.6 26.6 22.1 21.9 47.0 33.3 17.9 6.9 59.5 10.9 172.4 63.0 81.5 8.9 35.8 75.1 51.5 23.0 45.2 38.8 34.2 25.9 25.5 33.1 49.6 44.1 118.6 26.2 23.7 18.9 29.2 27.5 56.0 42.7 32.8 17.9 20.3 30.8 127.9 31.2 44.0 12.5 19.7 43.3 12.1 24.1 14.1 324.7 30.5 34.5 31.4 29.0 20.1 40.9 162.8 24.9 31.8 19.1 50.3 21.0 57.4 99.6 55.5 401.9 23.3 61.3 193.2 99.4 21.8 71.4 48.1 93.9 49.6 87.3 33.8 66.6 60.3 57.4 30.1 41.2 217.0 25.8 29.8 106.3 42.3 35.8 52.1 60.3 68.9 177.7 149.2 67.8 41.6 34.0 99.8 7.8 1.8 3.3 2.3 1.5 1.9 2.7 3.9 2.4 0.7 2.1 4.6 3.7 29.2 1.4 1.1 3.9 2.8 0.6 36.1 38.0 36.5 48.8 32.5 53.6 68.4 42.9 47.0 35.8 45.2 44.1 81.6 22.4 17.6 5.2 99.8 71.9 84.5 15.5 18.8 12.8 95.5 78.2 18.0 67.2 16.6 23.9 14.6 9.0 115.3 117.2 15.6 31.4 25.5 126.6 43.1 53.1 36.3 59.8 5.1 30.8 18.6 23.5 42.8 181.6 22.2 21.6 29.6 34.3 29.2 11.8 5.8 84.5 10.2 60.5 55.6 8.2 19.9 87.9 49.8 8.4 27.5 31.3 50.4 6.0 8.7 44.7 80.6 20.3 106.6 93.2 119.3 22.4 30.2 18.7 19.7 25.5 28.8 5.1 4.5 38.7 106.3 27.9 100.9 30.6 72.4 205.6 UBXN2B p37 ENSG00000215114 "UBX domain protein 2B" Q14CS0 8 58411359-58451501 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 42.8" "Group enriched" "Detected in all" 5 "granulocytes: 42.8;monocytes: 12.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045278 Uncertain Approved Nucleoplasm No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA045278: AB_10963578" "unprognostic (1.98e-3)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (2.15e-3)" "unprognostic (1.63e-1)" "unprognostic (2.22e-1)" "unprognostic (2.46e-1)" "unprognostic (8.71e-2)" "unprognostic (3.36e-1)" "unprognostic (5.97e-2)" "unprognostic (1.58e-2)" "unprognostic (1.54e-1)" "unprognostic (6.48e-3)" "unprognostic (1.26e-1)" "unprognostic (8.22e-2)" "unprognostic (2.00e-1)" "unprognostic (1.42e-2)" 7.9 9.1 10.3 12.0 11.4 15.4 11.0 14.0 12.5 6.6 9.2 8.7 7.7 8.1 10.8 5.8 8.5 8.6 9.8 11.9 9.0 15.7 18.8 9.7 9.1 11.2 8.9 9.0 8.8 16.1 7.9 7.6 11.2 9.5 9.2 13.4 12.9 8.5 9.0 6.4 7.8 9.8 9.6 10.1 8.2 9.5 9.8 11.9 14.2 11.0 9.4 8.9 4.3 12.8 11.1 20.2 16.9 20.9 3.0 1.5 11.7 6.7 12.3 8.2 10.6 8.8 20.4 13.0 13.4 8.3 22.2 9.9 25.1 12.1 11.5 10.0 12.7 16.2 17.0 11.0 12.6 14.5 15.1 5.4 19.0 3.8 18.9 19.5 10.2 19.7 11.4 23.8 7.4 11.3 26.0 16.0 22.1 38.6 4.8 14.5 7.5 8.9 26.4 16.8 6.2 25.4 11.6 11.7 19.7 16.5 23.7 17.3 2.3 6.3 13.4 13.7 14.0 12.4 13.3 18.0 20.6 13.6 8.5 15.8 11.9 18.0 4.3 11.0 4.2 3.4 4.1 3.6 5.9 3.3 4.9 4.3 42.8 5.4 12.9 2.9 5.3 5.3 10.3 11.4 14.0 12.5 11.9 9.0 11.2 8.9 11.2 9.6 9.8 12.8 4.0 9.6 8.7 27.7 11.4 5.7 10.6 10.3 4.0 16.0 13.7 11.7 18.4 10.0 9.0 11.0 22.9 15.9 10.4 15.9 9.8 11.2 35.8 8.6 9.3 4.7 12.0 13.5 55.3 11.1 17.6 9.5 10.7 11.8 23.5 13.3 4.6 17.1 23.0 11.8 62.4 9.6 14.2 32.4 12.4 61.8 10.5 27.5 8.8 21.5 26.0 13.6 15.5 43.2 41.4 10.8 8.2 14.7 8.4 10.4 15.5 29.7 8.9 25.6 0.0 13.9 8.5 20.4 17.8 9.3 6.7 8.6 10.9 8.6 9.1 10.4 USP16 Ubp-M ENSG00000156256 "Ubiquitin specific peptidase 16" Q9Y5T5 21 29024629-29054488 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 514.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021140 Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA021140: AB_1858668" "unprognostic (6.06e-2)" "unprognostic (3.14e-1)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (5.92e-2)" "unprognostic (5.79e-3)" "unprognostic (1.92e-1)" "unprognostic (8.99e-2)" "unprognostic (5.78e-2)" "unprognostic (7.40e-2)" "unprognostic (8.73e-2)" "unprognostic (8.65e-2)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (1.55e-1)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" 27.0 23.0 18.8 23.4 23.2 29.3 27.4 21.3 20.4 22.7 19.1 24.6 25.1 25.2 25.2 25.2 19.9 20.4 29.3 17.5 20.5 22.1 30.7 20.9 27.9 20.5 20.8 22.3 26.0 34.3 16.7 24.2 21.7 25.7 26.4 42.3 24.7 23.6 34.7 19.9 22.8 22.6 20.2 21.9 23.4 25.7 20.3 30.0 33.8 37.5 32.3 27.1 14.1 27.5 59.9 23.4 36.5 33.0 25.4 41.5 34.2 56.9 37.9 38.5 36.4 29.5 38.3 60.5 16.8 54.8 58.7 26.5 45.6 41.5 50.1 58.6 48.4 80.9 27.3 33.1 37.6 80.3 43.0 35.9 42.9 50.3 46.4 28.7 37.5 33.9 67.7 103.8 45.3 27.3 49.7 29.3 39.2 48.4 29.9 33.0 89.7 69.6 31.7 42.5 39.4 41.9 36.8 58.1 51.1 24.9 40.2 54.2 38.0 44.8 55.7 41.8 59.3 87.8 129.3 62.5 46.8 57.3 45.6 37.4 24.1 33.6 36.3 24.9 28.6 40.7 34.1 33.6 23.1 46.0 36.9 35.8 23.5 31.5 34.0 36.2 38.9 17.2 18.8 23.2 21.3 20.4 17.5 20.5 20.5 20.8 21.7 20.2 20.3 27.5 60.3 86.6 91.9 27.4 114.4 57.2 132.5 68.9 55.2 161.0 65.8 58.7 84.2 64.3 83.1 53.3 89.6 81.7 108.2 90.2 133.1 77.9 514.9 85.9 82.6 55.0 82.6 40.8 18.2 119.9 79.7 68.3 55.0 107.7 141.8 61.5 45.7 86.2 59.9 72.3 27.6 100.4 44.7 62.0 53.1 117.0 87.7 69.4 62.2 25.3 117.3 94.1 96.8 28.1 47.3 94.0 99.2 86.9 106.8 100.1 74.8 91.8 94.1 183.5 59.2 133.4 83.2 100.4 82.4 68.4 64.4 162.0 105.3 72.8 90.6 141.9 USP48 "FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31" ENSG00000090686 "Ubiquitin specific peptidase 48" Q86UV5 1 21678298-21783606 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030045, HPA030046" Approved Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Mitochondria, Cytosol" "HPA030045: AB_10670833, HPA030046: AB_10603325" "unprognostic (1.35e-1)" "unprognostic (3.72e-1)" "unprognostic (5.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.23e-1)" "unprognostic (7.00e-3)" "prognostic unfavorable (6.09e-8)" "unprognostic (1.04e-2)" "unprognostic (3.01e-3)" "unprognostic (9.30e-2)" "unprognostic (7.54e-2)" "unprognostic (4.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-1)" "unprognostic (5.70e-2)" "unprognostic (2.80e-2)" 25.8 47.5 18.7 26.6 24.5 43.5 26.4 31.0 26.4 26.9 21.6 24.4 21.7 25.3 20.4 23.0 22.3 18.9 21.6 19.3 20.4 18.2 23.8 23.1 35.1 20.1 20.4 31.1 24.6 25.2 26.9 27.3 21.7 23.5 26.0 57.0 31.2 18.6 23.1 29.5 28.7 22.9 18.5 36.0 32.5 20.6 20.8 26.9 28.6 19.5 34.5 23.1 24.6 36.0 43.9 20.5 47.0 34.0 40.1 49.0 46.4 54.0 36.5 35.3 46.6 19.1 43.2 49.1 35.6 48.8 27.5 39.2 59.0 43.4 53.6 48.3 42.1 104.3 75.7 34.5 35.5 53.0 53.7 39.8 36.6 36.1 39.7 48.1 106.1 36.2 83.8 133.2 44.0 21.9 44.2 68.5 29.7 44.5 36.8 61.3 47.2 57.3 40.7 36.2 57.1 35.6 50.4 45.7 122.7 62.3 23.4 63.0 76.1 37.7 30.9 46.7 31.8 105.6 81.7 48.1 36.3 64.5 56.6 82.1 19.5 35.0 12.2 9.4 13.9 28.6 17.8 17.9 21.1 29.8 20.5 13.1 16.8 12.2 10.9 15.3 21.4 12.6 18.7 24.5 31.0 26.4 19.3 20.4 20.1 20.4 21.7 18.5 20.8 36.0 37.9 54.5 42.1 32.0 55.4 22.2 25.1 30.3 33.0 86.5 22.2 24.5 65.3 21.5 24.4 20.2 62.6 61.4 48.3 17.8 25.4 28.5 71.4 33.3 48.5 32.5 21.7 88.1 66.4 20.0 56.3 42.0 33.1 41.4 49.9 200.4 27.5 22.1 29.2 50.5 74.2 31.3 32.6 22.6 28.1 47.7 34.8 34.4 58.7 52.5 55.9 30.7 36.0 54.3 112.3 23.8 16.4 51.6 150.1 20.7 24.1 20.2 27.3 69.2 32.9 51.7 39.8 52.7 47.4 35.1 25.7 32.6 41.8 54.8 31.6 21.6 VOPP1 "DKFZp564K0822, ECop, FLJ20532, GASP, WBP1L2" ENSG00000154978 "VOPP1 WW domain binding protein" Q96AW1 7 55436056-55572988 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 251.6" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 212.7;Plasma cells: 278.9;Rod photoreceptor cells: 220.7" "Cancer enriched" "Detected in all" 4 "glioma: 56.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 487.6;HDLM-2: 423.4;Karpas-707: 523.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.59e-2)" "unprognostic (2.51e-2)" "unprognostic (2.60e-2)" "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (3.69e-2)" "prognostic unfavorable (4.35e-5)" "unprognostic (8.65e-2)" "unprognostic (3.74e-1)" "unprognostic (5.98e-2)" "unprognostic (1.91e-3)" "unprognostic (5.15e-2)" "prognostic unfavorable (6.99e-8)" "unprognostic (3.32e-1)" "unprognostic (6.09e-2)" "unprognostic (1.23e-1)" "unprognostic (4.60e-2)" 30.4 17.4 63.0 67.1 51.4 38.1 23.9 48.9 53.1 35.3 54.8 41.4 35.5 30.1 27.2 20.5 38.9 32.9 24.3 50.5 62.6 48.0 23.2 33.4 99.2 60.3 70.2 28.6 22.1 27.2 57.4 20.8 57.6 23.5 42.4 251.6 38.8 21.3 48.6 14.3 47.4 28.8 61.4 76.4 39.7 10.3 74.3 114.4 21.0 36.2 78.5 39.8 23.4 63.8 487.6 92.3 48.0 46.7 104.0 58.5 21.1 121.0 109.3 102.7 102.1 43.6 118.3 107.6 81.6 109.3 168.9 76.6 50.8 101.1 109.6 423.4 29.1 0.2 53.1 60.7 23.9 39.1 46.7 50.5 52.1 92.9 35.7 69.3 137.2 35.7 27.9 523.5 175.5 36.0 15.7 26.8 105.9 60.7 55.3 25.6 48.9 260.1 114.4 46.0 97.1 36.9 70.1 49.2 25.5 80.4 55.0 47.4 119.0 104.8 157.5 140.7 128.3 250.0 191.2 115.6 44.7 35.6 163.2 17.7 10.0 35.7 24.9 11.5 19.4 75.0 31.6 33.3 25.8 38.6 24.3 26.8 25.7 30.1 19.8 28.2 41.9 25.3 63.0 51.4 48.9 53.1 50.5 62.6 60.3 70.2 57.6 61.4 74.3 63.8 43.7 3.2 9.8 47.7 113.8 12.6 25.6 14.3 12.0 56.3 10.7 5.1 7.9 27.1 17.0 49.7 212.7 1.8 56.7 44.0 9.8 38.9 11.5 27.1 18.0 40.8 53.3 13.9 44.9 32.5 7.1 20.5 19.9 21.8 6.3 21.3 44.3 25.1 38.5 42.1 71.2 45.7 16.2 105.6 145.9 11.8 19.3 64.4 39.2 87.1 131.3 86.5 81.4 19.1 16.8 59.5 41.3 22.6 278.9 28.2 39.9 10.0 18.7 220.7 32.9 12.4 19.4 3.7 27.0 8.6 8.4 1.2 51.0 5.9 34.6 27.4 VPS13B "CHS1, COH1" ENSG00000132549 "Vacuolar protein sorting 13 homolog B" Q7Z7G8 8 99013266-99877580 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 160.9;Excitatory neurons: 235.2;Inhibitory neurons: 253.2;Microglial cells: 204.2;Oligodendrocyte precursor cells: 217.1;Oligodendrocytes: 238.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043865 Approved "Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "HPA043865: AB_2678704" "unprognostic (4.23e-2)" "unprognostic (1.98e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-3)" "unprognostic (5.72e-2)" "unprognostic (6.08e-3)" "unprognostic (1.95e-1)" "unprognostic (1.62e-1)" "unprognostic (1.94e-1)" "unprognostic (1.65e-3)" "unprognostic (8.60e-2)" "unprognostic (5.95e-2)" "unprognostic (6.52e-2)" "unprognostic (5.19e-2)" "unprognostic (1.59e-1)" "unprognostic (8.93e-3)" "unprognostic (2.90e-1)" 4.0 3.0 2.4 4.4 3.3 13.4 4.7 4.5 3.0 5.4 8.2 3.6 2.3 7.2 3.8 4.4 4.9 4.4 2.3 2.0 1.9 3.8 3.1 3.5 4.8 3.6 2.4 8.1 3.4 6.8 2.3 4.0 3.6 4.9 3.7 6.0 3.2 4.1 2.9 4.0 3.0 5.4 2.2 4.2 3.6 4.9 4.9 7.1 4.7 4.4 5.0 4.5 3.7 5.3 8.6 6.1 7.2 5.3 13.3 15.9 3.6 5.4 9.9 5.3 7.0 3.6 4.3 4.8 6.9 9.3 3.9 3.9 5.0 5.0 9.6 7.7 4.6 10.3 6.5 2.8 4.3 5.0 7.4 10.3 4.6 8.5 12.2 7.4 7.6 7.9 7.9 12.4 6.1 5.3 10.5 2.9 2.3 8.9 2.2 8.3 5.1 9.1 3.5 8.0 2.1 6.0 8.4 4.0 4.0 6.4 7.2 5.6 10.8 7.9 7.4 7.1 4.6 5.0 6.2 12.7 6.0 7.9 5.6 3.0 1.2 2.8 1.2 1.0 1.1 3.3 1.0 0.9 0.5 1.6 1.7 1.1 6.1 0.7 2.3 0.6 1.4 0.5 2.4 3.3 4.5 3.0 2.0 1.9 3.6 2.4 3.6 2.2 4.9 5.3 15.5 19.2 12.2 160.9 24.2 8.8 7.6 9.2 15.4 15.1 8.9 7.6 12.8 10.0 11.9 3.7 37.5 4.9 21.6 7.3 0.0 4.9 8.6 10.9 42.7 11.5 9.0 22.9 235.2 4.6 4.0 18.2 28.1 12.7 3.8 10.4 6.4 5.2 6.5 11.8 253.2 11.9 8.2 15.6 11.3 9.6 27.7 17.8 7.2 204.2 15.0 9.4 17.5 217.1 238.1 4.0 11.0 20.7 19.2 6.2 9.8 2.9 8.2 12.9 0.0 15.7 14.7 23.9 7.3 13.0 9.7 4.2 19.5 14.6 7.4 5.7 VSX1 "PPCD, PPCD1, PPD" ENSG00000100987 "Visual system homeobox 1" Q9NZR4 20 25070885-25082141 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" "Developmental protein, DNA-binding" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 14.8;retina: 35.5" "Cell type enriched" "Detected in some" 23 "Bipolar cells: 465.9" "Not detected" "Not detected" "Region enriched" "Detected in all" 4 "cerebellum: 14.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Karpas-707: 4.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA079607 Approved Nucleoli NA NA "Cluster 6: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" Nucleoli "HPA079607: " "unprognostic (1.93e-1)" "unprognostic (6.63e-2)" "unprognostic (9.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.27e-1)" "unprognostic (1.97e-1)" "unprognostic (4.01e-1)" "unprognostic (8.64e-3)" "unprognostic (2.70e-2)" "unprognostic (1.35e-1)" "unprognostic (2.31e-9)" "unprognostic (1.53e-2)" "unprognostic (2.35e-1)" "unprognostic (3.07e-4)" "unprognostic (2.38e-1)" 0.0 0.9 3.4 0.0 3.3 0.5 0.1 14.8 2.8 0.1 1.7 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.2 2.9 3.5 0.0 0.2 0.0 0.1 3.2 3.3 1.4 0.4 0.7 2.9 0.0 3.2 0.2 0.1 35.5 0.1 0.3 0.5 0.2 0.1 0.0 3.0 0.1 0.1 0.2 3.4 0.7 0.2 0.2 0.0 0.2 0.0 3.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 4.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 3.4 3.3 14.8 2.8 2.9 3.5 3.2 3.3 3.2 3.0 3.4 3.4 0.0 0.0 0.0 6.5 0.1 0.0 0.0 0.0 0.0 465.9 0.1 0.0 1.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 5.3 0.0 19.6 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 WDR7 "KIAA0541, TRAG" ENSG00000091157 "WD repeat domain 7" Q9Y4E6 18 56651343-57029811 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 99.6;Excitatory neurons: 268.8;Inhibitory neurons: 223.0;Microglial cells: 111.5;Oligodendrocyte precursor cells: 146.3;Oligodendrocytes: 244.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042074, HPA051057" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA042074: AB_2677833, HPA051057: AB_2732563" "unprognostic (1.03e-1)" "unprognostic (1.32e-2)" "unprognostic (1.65e-2)" "unprognostic (1.40e-1)" "unprognostic (3.71e-2)" "unprognostic (3.66e-2)" "unprognostic (1.97e-1)" "unprognostic (3.58e-1)" "unprognostic (7.70e-2)" "unprognostic (9.21e-2)" "unprognostic (2.00e-2)" "unprognostic (5.05e-2)" "prognostic favorable (1.13e-5)" "unprognostic (4.80e-2)" "unprognostic (4.52e-3)" "unprognostic (7.76e-2)" "unprognostic (2.23e-2)" 5.9 7.6 13.2 5.9 14.2 7.2 4.9 7.0 19.8 4.8 3.1 5.4 4.1 4.8 5.3 4.4 4.2 5.3 5.9 16.2 11.1 5.3 7.4 5.0 7.4 14.6 8.8 4.2 4.2 9.2 8.4 4.7 14.7 7.5 4.9 18.8 4.2 5.7 8.2 4.3 4.3 5.6 7.8 6.2 4.9 4.6 9.6 10.3 9.1 9.6 5.8 5.0 4.5 16.0 4.7 7.7 8.7 4.9 13.5 7.8 2.2 9.2 7.8 7.4 8.8 3.1 2.9 13.0 3.6 8.3 6.3 4.9 8.8 7.2 9.2 15.1 5.4 12.3 5.8 2.8 8.1 18.7 15.0 6.7 5.9 9.9 6.6 6.1 9.3 6.1 6.0 17.5 9.3 4.6 13.0 5.5 3.7 2.4 5.1 5.8 6.7 6.3 5.7 8.4 11.3 5.6 6.5 3.1 4.3 7.4 4.9 5.2 8.3 10.5 5.3 3.2 5.0 17.4 14.2 13.9 8.6 9.3 7.2 4.0 3.0 5.5 3.6 4.4 4.5 2.4 4.0 3.7 3.6 2.2 4.2 3.8 2.6 4.6 5.5 1.7 5.2 2.0 13.2 14.2 7.0 19.8 16.2 11.1 14.6 8.8 14.7 7.8 9.6 16.0 8.7 3.2 4.8 99.6 7.5 2.9 1.9 2.3 2.8 24.5 3.4 2.4 12.5 5.7 6.8 0.0 31.3 2.0 7.7 5.8 3.9 3.2 21.0 4.4 6.0 6.6 8.4 8.2 268.8 3.6 1.2 6.3 7.7 3.9 10.8 9.0 9.3 8.9 5.8 26.9 223.0 2.7 0.0 16.2 2.8 7.0 5.6 11.3 0.0 111.5 8.8 7.1 10.3 146.3 244.7 2.6 2.6 8.2 10.1 2.6 4.5 3.2 5.7 26.3 6.6 10.7 5.8 2.0 1.7 5.8 2.4 0.7 9.9 9.3 4.1 1.6 WHRN "CIP98, DFNB31, PDZD7B, USH2D" ENSG00000095397 Whirlin Q9P202 9 114402080-114505473 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hearing "Deafness, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 104.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 49.5;Endometrial stromal cells: 13.9;Glandular and luminal cells: 39.6;Plasma cells: 14.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 97.9;U-266/70: 67.8;U-266/84: 89.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (6.06e-3)" "unprognostic (1.02e-1)" "unprognostic (9.96e-2)" "unprognostic (4.27e-3)" "unprognostic (4.59e-1)" "unprognostic (7.07e-2)" "unprognostic (3.66e-2)" "unprognostic (7.25e-2)" "unprognostic (6.13e-3)" "unprognostic (3.43e-2)" "prognostic favorable (2.28e-4)" "unprognostic (1.03e-1)" "unprognostic (1.71e-3)" "unprognostic (3.21e-2)" "unprognostic (1.92e-1)" "unprognostic (1.25e-2)" "unprognostic (3.44e-1)" 5.8 104.7 21.7 2.3 33.5 2.6 5.9 24.0 28.9 17.8 47.2 12.4 3.8 36.4 4.1 5.6 11.5 2.3 8.1 21.7 29.3 7.9 4.8 5.0 2.8 37.2 27.5 20.5 14.1 7.1 36.8 1.8 41.4 13.8 1.2 12.4 8.7 4.0 0.5 9.1 8.9 6.3 24.2 20.7 7.9 50.1 31.5 8.6 10.1 0.2 0.9 6.5 7.2 58.7 2.0 2.0 2.4 11.3 1.1 0.5 5.2 1.0 1.9 1.5 0.9 1.0 0.9 0.0 3.0 1.2 16.2 5.3 0.6 1.3 0.4 31.0 7.1 0.0 23.4 3.1 0.6 0.2 0.6 1.0 4.9 5.3 0.4 6.9 0.1 2.6 9.6 97.9 1.4 14.7 0.2 0.3 4.7 0.1 18.1 1.6 0.0 32.3 3.8 0.6 14.9 1.1 6.8 10.2 29.7 3.2 8.0 0.3 1.6 3.4 2.2 4.3 5.6 67.8 89.6 0.7 2.0 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.0 21.7 33.5 24.0 28.9 21.7 29.3 37.2 27.5 41.4 24.2 31.5 58.7 1.1 0.0 0.6 0.0 5.2 0.0 0.0 0.0 0.0 0.0 9.2 10.3 0.0 0.0 1.3 0.0 0.0 2.9 10.2 0.0 0.0 1.7 0.0 49.5 13.9 0.7 0.0 0.0 0.0 2.0 2.0 2.0 0.0 39.6 2.5 4.5 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 14.3 0.0 0.0 1.3 8.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 4.2 7.8 7.1 0.0 0.0 WIPF1 "WASPIP, WIP" ENSG00000115935 "WAS/WASL interacting protein family member 1" O43516 2 174559572-174682916 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 126.9" "Cell type enhanced" "Detected in many" "dendritic cells: 172.7;monocytes: 187.2;NK-cells: 245.1;Oligodendrocytes: 217.2;Plasma cells: 162.8;T-cells: 208.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 209.1;Karpas-707: 296.8;U-266/70: 233.0" "Low region specificity" "Detected in all" "HPA003739, CAB009737, HPA070706" Enhanced Approved "Plasma membrane,Cytosol" No No 520000 "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "CAB009737: AB_2288577, HPA003739: AB_1858783, HPA070706: AB_2686300" "unprognostic (4.76e-2)" "unprognostic (4.80e-2)" "unprognostic (1.49e-1)" "unprognostic (9.88e-2)" "unprognostic (1.87e-1)" "unprognostic (2.27e-3)" "unprognostic (2.05e-1)" "unprognostic (1.21e-1)" "unprognostic (7.22e-2)" "unprognostic (1.26e-1)" "unprognostic (3.25e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (3.65e-2)" "unprognostic (5.43e-2)" "unprognostic (1.58e-1)" "unprognostic (2.50e-2)" 31.0 14.7 14.2 93.0 37.2 56.8 21.0 36.1 20.5 30.6 11.1 26.0 18.2 22.4 11.5 14.2 14.4 34.8 16.0 14.9 28.8 13.0 16.4 31.8 126.9 46.2 38.6 12.3 7.3 12.9 4.8 33.5 42.3 14.9 20.8 3.4 17.7 23.0 5.9 9.9 32.5 29.1 27.9 89.7 21.8 4.7 35.1 66.4 15.4 11.5 110.5 31.5 17.0 53.8 0.7 7.0 16.3 0.2 40.4 70.9 16.9 31.1 26.4 12.1 18.7 1.9 1.4 209.1 9.2 47.0 15.6 0.5 2.8 0.0 15.1 144.8 4.1 106.5 26.9 0.0 15.1 94.9 167.2 29.6 5.1 27.7 2.6 16.0 25.0 18.7 3.3 296.8 34.4 0.1 106.6 87.1 19.1 0.0 1.4 90.0 6.6 37.9 11.3 0.7 2.6 33.8 0.3 8.8 18.7 30.4 0.4 46.8 21.2 41.0 11.5 30.1 29.9 233.0 165.2 113.7 60.4 64.7 111.7 41.5 35.4 87.2 71.6 37.3 59.4 35.1 47.6 71.1 26.1 28.6 38.0 51.4 166.1 57.4 43.7 11.2 57.7 54.7 14.2 37.2 36.1 20.5 14.9 28.8 46.2 38.6 42.3 27.9 35.1 53.8 32.1 19.2 21.7 27.7 134.5 12.5 6.3 0.9 2.8 2.1 3.3 4.3 10.5 1.5 4.6 3.7 25.0 2.0 172.7 0.3 5.9 1.7 40.2 3.3 21.9 30.8 4.9 30.1 5.3 11.6 82.5 40.5 9.7 2.1 67.2 2.1 36.8 3.7 86.2 0.0 7.2 1.6 0.0 142.2 128.0 96.9 25.1 139.8 26.6 98.4 187.2 1.2 245.1 120.6 217.2 16.8 0.8 18.0 162.8 5.0 0.2 35.9 0.1 3.4 13.1 15.7 21.4 4.4 4.1 1.2 11.1 4.1 208.1 8.8 2.1 3.1 XCR1 "CCXCR1, GPR5" ENSG00000173578 "X-C motif chemokine receptor 1" P46094 3 46017007-46027487 "G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.2" "Cell type enriched" "Detected in some" 5 "Langerhans cells: 10.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "myeloid DC: 3.8" "Lineage enriched" "Detected in single" 5 "dendritic cells: 3.8" "Cell line enhanced" "Detected in some" "HEL: 1.6;Karpas-707: 2.5;RT4: 2.0;U-266/84: 2.2;U-87 MG: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA013169 Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA013169: AB_1846211" "unprognostic (3.49e-3)" "unprognostic (4.23e-3)" "unprognostic (1.15e-2)" "unprognostic (5.91e-3)" "unprognostic (7.91e-2)" "unprognostic (8.53e-6)" "unprognostic (3.89e-6)" "unprognostic (9.27e-3)" "unprognostic (4.41e-3)" "unprognostic (3.40e-3)" "unprognostic (2.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.87e-1)" "unprognostic (5.98e-2)" "unprognostic (1.60e-2)" "unprognostic (1.30e-2)" "unprognostic (1.80e-1)" 0.9 0.1 0.1 3.8 0.2 3.0 0.6 0.8 0.7 0.7 0.5 1.1 1.7 0.5 4.5 1.9 0.5 3.0 0.5 0.5 0.1 0.3 1.1 1.4 11.2 0.3 0.1 0.9 0.1 0.1 0.0 4.3 0.3 0.6 1.1 0.6 0.2 0.6 0.1 2.7 1.7 1.5 0.0 7.2 1.2 0.4 0.3 8.8 0.5 0.4 4.6 1.6 0.2 0.7 0.0 0.8 0.3 0.0 0.0 0.0 0.7 0.3 0.8 0.0 0.0 0.7 0.0 0.7 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.4 0.0 0.0 0.4 0.3 0.5 2.5 0.0 0.8 0.4 0.0 0.0 0.4 0.0 0.3 0.0 0.3 0.3 2.0 0.1 0.0 0.0 0.2 0.0 0.7 0.2 0.0 0.0 0.4 0.9 0.2 0.1 1.2 2.2 0.7 1.7 0.0 0.2 0.7 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 3.8 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.3 0.1 0.2 0.8 0.7 0.5 0.1 0.3 0.1 0.3 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.8 10.2 1.5 0.0 2.0 1.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 XKR3 "MGC57211, XTES" ENSG00000172967 "XK related 3" Q5GH77 22 16783412-16821699 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 43 "testis: 8.1" "Cell type enriched" "Detected in some" 10 "Early spermatids: 159.6" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.6" "Cell line enriched" "Detected in some" 15 "Karpas-707: 230.8" "HPA003379, HPA035081" Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA003379: AB_10602682, HPA035081: AB_2674451" "unprognostic (4.57e-1)" "unprognostic (3.37e-1)" "unprognostic (3.11e-2)" "unprognostic (3.13e-2)" "unprognostic (5.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.3 0.5 0.0 0.0 15.2 230.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.9 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 159.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.3 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 YIF1B FinGER8 ENSG00000167645 "Yip1 interacting factor homolog B, membrane trafficking protein" Q5BJH7 19 38303558-38317273 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039328, HPA055257, HPA062675" Approved Approved "Golgi apparatus,Vesicles" NA NA 37000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Vesicles "Golgi apparatus" "HPA039328: AB_2676445, HPA055257: AB_2682762, HPA062675: AB_2684830" "unprognostic (2.51e-1)" "unprognostic (3.34e-1)" "unprognostic (1.38e-1)" "unprognostic (6.81e-2)" "unprognostic (1.45e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.53e-5)" "unprognostic (1.37e-1)" "unprognostic (1.45e-2)" "unprognostic (5.53e-2)" "prognostic favorable (1.88e-4)" "unprognostic (4.57e-2)" "unprognostic (2.40e-2)" "unprognostic (3.69e-1)" "unprognostic (1.26e-1)" "unprognostic (2.64e-1)" "unprognostic (3.94e-3)" 30.1 30.7 29.3 33.0 32.4 69.1 26.7 37.0 38.3 33.5 29.0 26.6 20.4 24.1 10.9 33.2 25.6 16.5 40.6 30.2 32.6 27.2 58.3 35.7 32.1 36.3 30.9 26.7 27.1 16.9 29.1 23.5 38.6 23.7 16.1 13.6 30.2 12.5 35.0 26.0 24.0 18.1 33.4 47.7 22.0 23.1 34.0 20.9 19.8 26.7 20.9 26.8 25.6 38.5 43.7 108.9 48.3 57.5 68.4 63.5 37.8 103.2 79.0 75.7 110.7 53.5 32.6 75.7 44.4 121.1 81.5 27.4 85.9 54.6 28.7 81.1 43.3 117.0 48.2 56.5 94.8 82.4 132.9 52.3 47.9 78.0 33.8 76.1 71.3 99.4 152.9 205.3 68.5 46.0 87.6 98.9 37.0 74.9 33.7 89.0 58.6 117.9 48.9 40.6 34.8 58.1 34.5 76.7 55.4 37.2 29.9 163.2 68.8 74.6 73.2 108.4 83.9 76.4 122.1 51.8 96.1 150.5 54.6 81.9 155.7 179.0 60.8 119.4 54.4 49.3 57.3 54.8 300.3 42.7 46.7 47.5 42.8 44.0 70.8 127.0 59.0 120.2 29.3 32.4 37.0 38.3 30.2 32.6 36.3 30.9 38.6 33.4 34.0 38.5 27.4 0.0 5.5 5.5 22.8 17.7 19.4 25.8 18.2 12.2 22.6 18.7 4.7 18.6 14.2 22.0 12.5 44.7 17.0 16.0 0.0 39.4 6.3 17.5 18.2 23.9 14.4 33.2 7.3 27.7 52.9 23.8 16.3 18.6 22.9 43.4 37.1 30.5 94.4 11.8 7.4 24.7 32.6 42.3 37.4 8.5 9.0 53.3 35.6 3.7 34.4 20.8 16.5 4.0 12.7 15.5 13.5 9.1 69.4 14.8 8.1 16.1 20.7 15.5 6.6 11.1 40.3 20.6 31.9 30.7 20.0 27.6 18.8 26.2 25.9 19.5 Z84492.1 ENSG00000272104 "Novel protein" 3 50350892-50367923 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 4.8;Karpas-707: 6.5" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "unprognostic (2.51e-1)" "unprognostic (9.06e-2)" 1.7 0.5 2.4 0.9 2.2 1.1 1.7 1.9 3.7 1.5 1.0 2.8 4.6 0.8 4.0 1.2 1.6 0.8 0.3 1.5 3.2 2.5 0.4 0.5 4.5 1.8 1.6 3.0 3.5 1.2 0.7 0.2 1.7 2.7 1.1 0.4 4.3 1.0 0.6 4.4 4.7 0.5 1.4 2.6 3.6 1.3 2.4 1.2 3.2 0.1 1.8 0.6 0.0 1.7 1.6 0.0 0.0 1.0 1.1 0.0 0.3 1.7 1.1 0.3 1.3 0.0 1.0 0.9 1.5 0.0 0.1 0.9 0.0 0.6 0.9 1.8 0.4 0.0 1.3 0.0 0.4 0.0 4.8 0.0 0.8 0.6 0.0 0.2 0.0 2.4 0.3 6.5 0.0 0.6 1.8 0.0 0.6 1.6 0.0 0.6 0.3 2.6 0.3 0.0 1.2 3.0 0.0 1.2 0.2 0.3 1.1 0.0 0.0 0.3 0.1 0.0 0.5 1.6 2.5 1.1 0.0 0.4 0.0 4.8 0.1 3.6 5.8 0.3 8.4 8.3 10.5 8.6 0.1 9.3 14.2 8.2 0.5 10.4 0.7 1.6 15.4 3.0 2.4 2.2 1.9 3.7 1.5 3.2 1.8 1.6 1.7 1.4 2.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZBP1 "C20orf183, DAI, dJ718J7.3, DLM-1, DLM1" ENSG00000124256 "Z-DNA binding protein 1" Q9H171 20 57603846-57620576 "Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Necrosis" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.7;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in some" "B-cells: 34.0;dendritic cells: 42.7;NK-cells: 53.5;Plasma cells: 189.2;T-cells: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 34.1;U-266/70: 16.6;U-266/84: 22.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA041256 Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA041256: AB_2677380" "unprognostic (5.78e-3)" "unprognostic (9.86e-2)" "unprognostic (6.14e-2)" "unprognostic (6.20e-2)" "unprognostic (6.65e-2)" "unprognostic (1.05e-4)" "unprognostic (1.37e-2)" "unprognostic (1.31e-1)" "unprognostic (1.19e-3)" "unprognostic (1.38e-3)" "unprognostic (7.19e-2)" "unprognostic (2.58e-1)" "unprognostic (1.58e-8)" "unprognostic (8.29e-2)" "unprognostic (1.73e-1)" "unprognostic (4.65e-2)" "unprognostic (9.79e-2)" 2.6 1.4 0.6 18.8 0.7 28.7 3.6 4.6 2.8 2.1 0.1 9.8 13.1 1.9 2.2 2.1 1.0 7.8 1.9 1.5 0.0 1.3 2.1 5.1 23.9 0.6 0.2 1.8 2.0 0.2 0.4 1.3 1.3 1.8 10.8 4.1 6.2 1.6 0.8 3.9 10.6 1.2 0.7 21.8 8.4 2.2 0.4 5.0 2.7 1.3 25.1 8.5 0.8 2.9 0.8 0.6 1.9 3.5 0.6 0.5 1.0 0.6 0.3 0.2 0.9 3.0 1.6 9.3 0.7 0.0 1.1 1.5 0.0 1.1 0.0 0.8 2.0 2.9 5.5 1.4 0.5 2.5 2.2 0.0 0.4 1.1 0.9 1.8 0.4 1.5 1.2 34.1 1.3 4.7 1.5 4.8 2.2 0.5 4.1 1.4 0.2 10.0 0.0 4.3 1.9 2.0 0.3 1.6 1.4 1.3 1.3 1.4 1.6 4.3 1.5 2.8 1.6 16.6 22.8 4.1 1.6 2.8 0.8 1.6 3.8 17.5 18.8 3.9 12.5 16.2 12.6 11.4 4.4 12.1 5.6 7.8 38.0 19.6 2.4 0.2 18.4 7.0 0.6 0.7 4.6 2.8 1.5 0.0 0.6 0.2 1.3 0.7 0.4 2.9 1.2 0.0 0.6 0.0 34.0 0.3 1.0 0.2 0.0 0.0 0.5 0.3 1.0 0.0 0.0 0.0 2.1 0.1 42.7 12.9 0.0 0.1 0.1 0.1 0.2 0.5 0.0 0.8 0.0 0.2 0.0 0.5 3.1 0.4 3.8 0.0 0.0 0.0 1.0 0.0 0.1 1.1 0.0 1.0 0.4 0.0 0.0 2.1 14.2 0.0 3.1 0.5 53.5 0.0 0.1 1.3 3.4 0.0 189.2 1.8 0.8 0.2 0.0 0.3 0.0 1.5 0.8 0.0 0.0 0.0 0.3 0.0 25.8 0.0 1.0 0.8 ZBTB44 "BTBD15, HSPC063, ZNF851" ENSG00000196323 "Zinc finger and BTB domain containing 44" Q8NCP5 11 130226677-130314917 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052589 Approved Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA052589: AB_2681874" "unprognostic (4.04e-2)" "unprognostic (1.33e-1)" "unprognostic (8.03e-2)" "unprognostic (7.60e-2)" "unprognostic (4.13e-2)" "unprognostic (5.63e-2)" "unprognostic (2.19e-1)" "unprognostic (2.47e-2)" "unprognostic (1.93e-2)" "unprognostic (3.56e-2)" "unprognostic (1.38e-3)" "unprognostic (3.34e-1)" "unprognostic (8.45e-3)" "unprognostic (6.39e-2)" "unprognostic (2.19e-1)" "unprognostic (1.43e-1)" "unprognostic (1.78e-2)" 13.0 11.2 14.0 10.5 16.4 12.8 15.6 21.3 13.8 12.6 9.1 11.3 8.8 12.0 17.5 11.5 14.6 8.7 11.3 13.2 12.2 25.4 14.1 11.5 15.7 10.4 13.6 15.8 11.4 16.0 8.2 12.6 10.8 10.6 9.8 16.7 14.2 11.6 36.9 14.6 10.9 9.4 11.1 14.3 10.4 36.9 15.0 25.3 13.4 31.4 16.4 12.3 12.0 16.5 14.0 9.1 13.6 12.4 18.9 18.4 14.9 8.3 14.7 7.5 9.4 15.7 42.5 44.0 42.8 14.0 18.4 14.0 19.1 18.0 12.7 37.8 11.6 65.3 10.2 9.7 11.2 34.2 47.2 12.3 19.2 12.8 27.8 15.9 11.5 26.3 18.6 63.8 8.5 11.1 33.4 24.2 12.0 21.1 13.6 21.8 12.1 15.0 21.4 14.2 28.4 12.1 24.4 16.3 6.5 12.9 29.8 26.9 12.8 15.3 13.5 6.9 9.5 12.2 19.4 40.0 4.0 42.4 14.1 0.7 0.7 0.9 2.0 0.8 1.3 1.1 1.2 1.2 0.8 1.3 1.0 1.2 2.0 1.5 0.6 1.6 1.6 0.4 14.0 16.4 21.3 13.8 13.2 12.2 10.4 13.6 10.8 11.1 15.0 16.5 32.6 25.6 39.4 33.0 42.9 72.1 33.9 33.8 46.7 44.4 56.6 41.4 49.3 40.0 28.6 77.3 58.4 34.0 61.6 18.3 19.6 26.6 56.5 47.9 38.7 33.8 19.3 55.2 50.5 20.4 18.6 40.2 16.3 85.3 10.2 56.6 38.6 43.4 14.9 20.2 48.5 26.8 24.4 42.5 29.9 58.3 73.7 30.0 23.2 39.4 33.6 23.2 104.0 64.3 125.7 21.4 16.9 79.0 27.1 51.7 27.7 69.7 30.5 37.6 39.5 64.4 26.5 103.4 61.6 39.8 82.1 26.8 40.2 42.3 33.1 40.9 ZCCHC18 "PNMA7B, SIZN2" ENSG00000166707 "Zinc finger CCHC-type containing 18" P0CG32 X 104112131-104115842 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.0;ovary: 4.2" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 4.2;NK-cells: 9.2;Oligodendrocyte precursor cells: 6.6;Sertoli cells: 6.6" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.5;Karpas-707: 4.6;SH-SY5Y: 3.1" "Low region specificity" "Detected in all" "HPA034940, HPA078516" Uncertain Approved Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA034940: AB_10671098, HPA078516: " "unprognostic (7.20e-2)" "unprognostic (7.71e-4)" "unprognostic (8.29e-2)" "unprognostic (4.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-3)" "unprognostic (2.20e-2)" "unprognostic (3.22e-2)" "unprognostic (7.59e-2)" "unprognostic (3.34e-1)" "unprognostic (4.44e-6)" "unprognostic (4.05e-2)" "unprognostic (1.02e-6)" "unprognostic (3.82e-2)" "unprognostic (4.02e-1)" "unprognostic (3.91e-2)" "unprognostic (4.14e-3)" 0.5 0.8 3.0 1.3 2.9 0.4 0.3 2.9 3.0 1.8 1.1 0.7 0.3 1.5 0.2 0.3 1.3 0.4 0.5 2.7 5.0 0.4 0.1 0.4 2.0 2.2 2.5 4.2 0.9 0.0 1.6 0.1 2.2 0.8 0.3 1.2 0.2 0.6 0.1 0.2 2.0 0.6 2.4 2.2 0.5 1.0 4.9 0.4 0.3 0.1 2.0 0.6 0.7 2.1 0.0 0.1 1.9 1.3 0.1 0.0 0.1 0.4 0.0 0.3 0.3 0.1 0.0 2.5 0.0 0.1 0.4 0.0 1.1 0.0 0.1 0.7 0.9 0.4 0.1 0.0 0.2 1.4 0.4 0.1 0.0 0.2 0.0 1.1 0.3 0.1 0.0 4.6 0.1 0.0 0.0 0.0 1.0 0.0 0.3 1.7 0.4 0.0 0.2 0.2 1.3 3.1 0.1 0.0 0.0 0.2 0.0 0.1 0.8 0.1 0.5 0.1 0.6 0.1 0.0 1.2 0.0 1.4 0.4 0.0 0.0 0.0 0.4 0.0 0.6 0.7 0.3 0.5 0.0 0.8 0.3 0.4 0.0 0.0 0.0 0.0 0.2 0.1 3.0 2.9 2.9 3.0 2.7 5.0 2.2 2.5 2.2 2.4 4.9 2.1 0.9 0.0 0.6 3.3 4.0 0.1 0.2 0.0 0.0 0.8 0.3 0.3 0.7 0.0 1.3 1.8 0.0 0.0 1.7 0.0 0.0 0.1 0.1 0.6 0.9 1.2 4.2 0.8 2.6 0.2 0.0 1.2 0.0 0.3 0.0 1.3 0.7 0.0 0.0 1.7 1.5 0.0 0.0 0.3 0.4 0.3 1.5 0.1 1.8 0.0 0.1 3.4 9.2 6.6 0.3 0.0 0.0 1.2 1.7 0.1 0.0 0.2 1.5 1.0 6.6 0.2 2.4 0.0 0.2 0.1 0.0 0.0 3.6 1.0 0.0 0.1 ZDHHC2 "DHHC2, ZNF372" ENSG00000104219 "Zinc finger DHHC-type palmitoyltransferase 2" Q9UIJ5 8 17156482-17224799 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 77.8" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023331, HPA023334" Uncertain Approved "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA023331: AB_2671165, HPA023334: " "unprognostic (8.92e-2)" "unprognostic (4.23e-1)" "unprognostic (1.80e-2)" "unprognostic (2.53e-1)" "unprognostic (6.89e-2)" "unprognostic (2.25e-1)" "unprognostic (6.12e-2)" "unprognostic (1.78e-2)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" "prognostic favorable (3.24e-4)" "unprognostic (5.00e-2)" "unprognostic (3.87e-1)" "unprognostic (2.87e-2)" "unprognostic (5.10e-2)" 10.3 24.4 10.3 11.0 8.9 31.7 7.5 43.9 14.8 13.4 13.5 15.3 10.5 7.6 11.8 3.9 13.8 7.0 9.7 8.0 22.4 26.4 6.5 14.3 9.3 17.7 13.6 11.8 30.7 28.9 9.5 6.9 16.6 11.7 11.2 77.8 19.6 12.9 17.9 1.8 10.3 9.5 13.5 10.7 16.3 16.6 26.3 12.7 33.5 37.2 11.7 19.7 4.4 22.0 2.3 12.4 23.7 4.9 20.3 36.0 13.8 41.5 49.9 23.0 27.2 3.9 34.3 26.1 15.9 36.2 57.9 1.5 32.2 20.5 42.5 16.8 16.2 23.2 16.8 5.0 20.3 24.7 2.6 15.3 3.2 28.8 26.1 52.7 38.4 29.8 2.7 66.5 28.1 0.6 18.3 15.2 15.0 18.8 19.1 17.9 23.7 9.5 41.8 26.7 12.7 8.3 17.8 0.0 3.8 34.9 1.0 10.9 32.0 11.6 35.2 26.0 41.7 13.2 53.7 30.1 32.1 22.2 5.3 1.6 1.2 2.6 1.9 1.3 3.3 2.5 2.4 2.3 1.1 2.1 2.1 2.3 0.9 2.2 0.8 2.3 1.3 0.7 10.3 8.9 43.9 14.8 8.0 22.4 17.7 13.6 16.6 13.5 26.3 22.0 20.9 44.8 25.4 34.0 18.8 3.1 15.3 4.1 1.8 54.4 21.1 8.0 15.2 15.7 10.5 51.5 77.2 0.5 27.1 8.7 21.5 22.2 8.3 19.3 6.8 11.6 19.7 22.7 49.8 33.4 1.2 10.4 9.7 25.4 8.2 10.9 10.0 8.0 12.6 11.8 20.1 16.2 6.1 28.6 16.1 11.7 5.0 22.2 23.2 37.5 12.9 40.6 8.2 26.7 61.3 37.0 10.7 3.0 14.0 31.3 6.1 26.1 7.7 90.2 13.1 9.1 7.5 6.6 3.9 3.3 2.7 0.4 17.0 8.7 17.0 36.5 ZFAT "KIAA1485, ZFAT1, ZNF406" ENSG00000066827 "Zinc finger and AT-hook domain containing" Q9P243 8 134477788-134713049 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 31.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.5;dendritic cells: 35.6;Early spermatids: 49.3;Late spermatids: 53.0;Syncytiotrophoblasts: 126.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 24 "plasmacytoid DC: 34.5" "Lineage enriched" "Detected in many" 24 "dendritic cells: 34.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020989, HPA063592" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 2: Karpas-707 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear bodies" Nucleoplasm "HPA020989: AB_2670552, HPA063592: AB_2685051" "unprognostic (2.00e-1)" "unprognostic (1.45e-1)" "unprognostic (4.62e-3)" "unprognostic (5.91e-3)" "unprognostic (2.45e-1)" "unprognostic (5.12e-2)" "unprognostic (1.31e-4)" "unprognostic (6.27e-2)" "unprognostic (2.68e-2)" "unprognostic (1.28e-1)" "unprognostic (2.43e-2)" "unprognostic (1.13e-1)" "unprognostic (1.90e-2)" "unprognostic (1.80e-1)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (1.33e-1)" 2.2 1.4 0.8 2.8 0.9 1.2 2.1 0.5 1.4 1.8 1.7 4.7 2.3 2.5 2.0 2.6 2.0 1.2 2.2 1.0 0.9 9.7 1.5 2.2 3.7 1.3 0.6 2.1 2.3 2.7 1.5 31.1 0.8 2.2 1.7 2.7 1.8 2.1 7.5 1.9 2.1 2.6 0.5 2.5 1.9 2.3 0.7 3.2 1.6 4.3 2.9 2.8 1.8 0.7 4.1 6.5 2.3 2.9 4.4 4.3 2.1 4.4 3.8 3.9 4.0 4.5 5.2 4.7 3.8 4.6 2.3 3.2 4.7 5.6 5.1 3.9 6.0 8.7 5.7 3.3 3.4 4.9 4.3 3.5 2.8 4.3 5.7 3.6 4.9 1.7 3.4 8.4 3.4 5.6 5.1 0.8 3.2 4.2 3.9 3.1 3.0 2.0 3.8 6.2 2.8 2.1 4.5 3.4 3.7 2.6 2.8 4.6 5.4 2.3 3.4 3.3 5.0 3.0 4.4 4.5 2.8 3.6 4.9 1.1 0.6 1.4 0.4 0.8 0.4 0.9 0.4 0.7 0.5 1.1 0.6 0.4 1.0 0.1 0.5 34.5 0.3 0.9 0.8 0.9 0.5 1.4 1.0 0.9 1.3 0.6 0.8 0.5 0.7 0.7 3.5 3.2 3.3 14.4 7.0 1.5 1.2 1.0 1.8 5.3 4.0 1.4 2.0 1.5 3.1 1.8 4.2 74.5 35.6 1.5 0.0 2.1 49.3 2.6 5.0 2.8 0.0 0.8 24.4 1.5 17.2 2.7 3.6 3.1 2.5 2.9 0.7 1.4 8.4 1.7 18.9 1.4 0.0 3.8 2.1 53.0 3.4 4.2 8.8 14.0 3.5 2.1 4.1 9.5 12.6 3.3 0.5 2.6 17.0 1.6 1.1 12.2 1.1 6.0 0.0 3.7 2.5 2.9 5.5 1.9 1.7 126.7 3.6 3.2 1.3 1.5 ZMAT1 KIAA1789 ENSG00000166432 "Zinc finger matrin-type 1" Q5H9K5 X 101882288-101932079 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 190.3;Oligodendrocyte precursor cells: 111.1;Oligodendrocytes: 112.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 8.2;U-266/70: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012827 Enhanced Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA012827: AB_1859070" "unprognostic (9.30e-2)" "unprognostic (4.13e-2)" "unprognostic (2.51e-2)" "unprognostic (2.80e-1)" "unprognostic (1.08e-1)" "unprognostic (1.08e-5)" "unprognostic (1.20e-3)" "unprognostic (2.22e-2)" "unprognostic (3.70e-2)" "unprognostic (6.09e-2)" "prognostic favorable (1.72e-5)" "unprognostic (6.33e-3)" "unprognostic (1.72e-2)" "unprognostic (3.05e-1)" "unprognostic (5.28e-2)" "unprognostic (2.21e-1)" "unprognostic (1.38e-2)" 6.4 9.3 11.1 2.8 11.5 6.3 7.5 10.5 15.1 8.0 10.6 7.3 1.8 5.5 21.2 2.4 10.0 2.1 7.9 10.7 10.7 18.3 9.7 5.7 6.6 11.5 10.9 15.2 10.3 4.3 34.8 0.7 11.0 10.7 1.3 9.4 6.7 3.7 2.6 3.0 7.5 1.3 11.1 13.8 5.8 6.7 10.9 3.2 25.0 1.5 2.6 6.0 4.8 12.1 0.2 0.0 1.0 1.0 0.0 0.0 0.1 0.4 0.0 0.0 0.4 0.0 1.2 1.8 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.2 0.2 0.7 1.9 0.0 8.2 0.6 0.0 0.1 0.1 1.3 0.0 0.1 1.5 0.0 0.1 2.3 0.0 0.4 1.1 0.7 0.0 0.1 1.1 1.4 2.1 2.0 0.6 0.0 0.0 0.1 4.1 0.3 0.0 0.4 2.0 0.6 0.8 0.3 0.5 0.2 0.1 0.4 0.6 0.3 0.4 0.0 0.9 0.4 0.3 0.2 0.1 0.1 0.9 0.2 0.1 11.1 11.5 10.5 15.1 10.7 10.7 11.5 10.9 11.0 11.1 10.9 12.1 18.9 16.0 31.2 190.3 30.2 4.1 7.6 0.2 7.4 38.1 18.2 12.3 25.4 11.5 14.4 14.7 43.8 0.1 16.5 0.6 3.9 5.0 14.9 28.2 3.7 16.8 10.3 6.9 30.7 2.7 0.0 10.3 2.0 21.6 15.8 51.5 13.6 10.6 3.3 16.8 32.8 2.8 0.0 9.7 11.1 9.7 1.8 11.7 7.2 71.2 10.7 25.8 10.3 111.1 112.8 1.5 1.6 1.2 7.4 6.1 2.7 5.7 13.0 57.5 0.0 27.5 9.0 22.4 10.2 3.2 2.8 0.1 16.3 5.4 2.6 4.3 ZNF267 HZF2 ENSG00000185947 "Zinc finger protein 267" Q14586 16 31873807-31917357 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 131.1;Macrophages: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA003866 Approved Approved Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA003866: AB_1080698" "unprognostic (2.73e-2)" "unprognostic (4.24e-2)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (4.84e-2)" "unprognostic (6.24e-2)" "unprognostic (5.60e-3)" "unprognostic (8.64e-2)" "unprognostic (6.73e-2)" "unprognostic (1.31e-1)" "unprognostic (3.60e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (1.58e-6)" "unprognostic (2.34e-1)" "unprognostic (3.34e-2)" "unprognostic (3.95e-1)" "unprognostic (8.21e-2)" 6.3 3.7 3.2 18.6 3.8 27.4 7.3 3.4 11.6 5.5 5.4 6.1 7.1 6.7 3.1 7.1 6.0 10.0 4.4 2.9 4.4 5.0 6.6 9.3 17.9 4.6 4.4 6.2 4.8 4.5 2.3 10.0 4.8 5.2 7.1 2.5 5.3 3.9 6.1 4.0 5.9 5.9 4.2 13.2 6.8 9.8 6.4 11.4 5.9 6.6 18.4 13.6 4.4 5.5 8.8 10.0 8.8 7.0 6.2 7.2 26.9 7.0 11.7 9.6 14.7 17.9 13.7 15.6 12.6 5.7 9.6 11.3 14.4 11.4 18.5 23.6 12.1 15.8 5.6 16.1 5.6 17.0 35.3 10.3 7.7 13.6 9.7 7.0 14.0 11.8 25.9 35.9 13.2 12.2 11.4 11.3 8.2 6.8 5.8 11.4 24.8 13.7 10.9 38.8 2.8 4.3 10.8 9.6 10.3 15.3 5.7 23.6 16.8 9.3 8.5 8.2 12.0 20.1 12.3 15.7 12.3 13.6 5.7 36.6 24.0 33.4 12.4 23.4 18.6 21.2 16.2 12.5 18.8 15.9 12.6 15.2 75.3 16.5 27.5 11.3 20.3 12.3 3.2 3.8 3.4 11.6 2.9 4.4 4.6 4.4 4.8 4.2 6.4 5.5 23.7 9.6 8.0 3.6 37.0 31.9 39.6 15.2 13.1 4.5 12.3 12.2 5.6 8.6 14.0 3.7 0.0 14.1 27.2 5.4 7.9 19.1 23.3 34.8 10.3 33.5 7.7 10.9 7.1 20.0 10.4 17.2 13.7 31.4 60.3 5.4 7.5 2.8 21.5 11.8 3.7 7.0 14.2 25.3 131.1 8.8 5.9 82.2 14.2 15.0 68.5 5.0 22.6 9.5 7.7 49.7 8.0 3.4 19.9 30.1 4.2 12.4 26.2 3.9 0.0 10.8 12.2 20.7 29.6 33.1 25.6 8.3 47.6 5.9 5.6 48.9 ZNF460 "HZF8, ZNF272" ENSG00000197714 "Zinc finger protein 460" Q14592 19 57280051-57294069 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 22.2;Squamous epithelial cells: 21.5" "Cancer enhanced" "Detected in many" "stomach cancer: 3.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 13.5" "HPA053004, HPA066506" Uncertain Approved Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA053004: AB_2682012, HPA066506: AB_2685681" "unprognostic (2.57e-1)" "unprognostic (1.72e-1)" "unprognostic (1.28e-2)" "unprognostic (3.65e-2)" "unprognostic (1.58e-2)" "unprognostic (3.20e-1)" "unprognostic (8.04e-2)" "unprognostic (2.52e-1)" "unprognostic (2.19e-1)" "unprognostic (2.86e-1)" "unprognostic (2.89e-2)" "unprognostic (1.68e-1)" "unprognostic (1.32e-1)" "unprognostic (2.12e-1)" "unprognostic (1.62e-1)" "unprognostic (2.08e-2)" "unprognostic (4.10e-2)" 1.9 4.9 5.1 0.7 7.9 6.0 1.6 7.9 6.2 1.4 3.6 0.9 0.3 1.0 0.8 1.3 1.0 1.0 1.4 3.4 4.6 1.1 1.5 1.3 0.9 7.8 6.8 2.3 1.0 1.3 1.7 1.4 9.2 1.1 0.6 2.6 1.3 1.1 1.5 1.9 0.7 1.1 4.8 1.4 0.9 1.8 5.2 1.0 1.4 1.3 1.0 1.1 1.3 19.7 1.2 1.9 1.5 2.1 1.5 1.3 3.8 0.8 1.2 0.9 2.8 2.4 0.7 1.9 0.9 1.0 0.8 0.8 2.0 1.0 1.6 1.4 3.9 1.8 1.6 1.2 1.7 3.2 2.0 0.7 1.8 2.5 2.8 0.7 0.6 2.0 1.8 13.5 1.1 0.9 1.9 0.5 2.1 1.0 1.8 1.4 2.1 0.9 0.6 2.4 1.9 1.0 2.1 1.1 1.2 1.0 0.9 2.2 0.9 2.8 3.3 0.4 1.7 5.7 2.7 3.1 1.0 1.2 0.9 0.0 0.5 1.0 0.7 1.1 0.8 0.8 0.5 0.4 0.1 2.2 1.2 0.5 1.2 0.8 0.7 0.0 1.1 0.7 5.1 7.9 7.9 6.2 3.4 4.6 7.8 6.8 9.2 4.8 5.2 19.7 7.9 3.2 1.5 3.9 11.6 3.1 3.6 0.7 22.2 4.3 4.1 2.8 5.9 1.5 2.0 0.0 0.0 1.4 6.6 1.3 0.0 1.5 3.4 7.0 9.5 4.9 0.0 11.2 6.2 0.4 2.0 7.3 10.2 13.1 0.0 4.7 7.1 2.0 1.1 8.4 5.9 1.2 4.1 1.9 2.2 0.7 1.8 3.3 1.8 1.9 4.0 2.4 4.1 2.5 13.3 1.7 0.2 1.5 16.3 3.0 0.7 0.8 2.4 3.2 0.0 8.1 8.4 3.6 1.4 21.5 2.4 2.6 7.8 3.6 1.3 4.4 ZNF484 "BA526D8.4, FLJ33884" ENSG00000127081 "Zinc finger protein 484" Q5JVG2 9 92844182-92878038 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.7;Inhibitory neurons: 22.6;Oligodendrocyte precursor cells: 27.2;Oligodendrocytes: 19.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028973 Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nuclear membrane, Cytosol" "HPA028973: AB_10610703" "unprognostic (5.52e-2)" "unprognostic (3.05e-2)" "unprognostic (1.72e-1)" "unprognostic (6.05e-2)" "unprognostic (5.69e-2)" "unprognostic (3.86e-1)" "unprognostic (6.45e-2)" "unprognostic (1.91e-1)" "unprognostic (6.04e-2)" "unprognostic (9.84e-2)" "unprognostic (3.12e-1)" "unprognostic (1.91e-2)" "unprognostic (4.03e-2)" "unprognostic (3.74e-1)" "unprognostic (4.77e-1)" "unprognostic (6.49e-2)" "unprognostic (1.51e-1)" 2.0 2.2 1.9 2.0 2.7 4.1 2.2 9.7 3.3 2.5 0.0 1.6 1.2 2.4 1.7 1.3 2.1 1.6 1.6 1.8 3.4 2.4 1.9 2.0 2.4 2.8 2.8 3.1 1.3 3.6 2.1 2.8 3.1 2.3 1.8 5.3 1.5 2.0 1.1 1.3 1.5 2.1 2.7 2.9 2.1 1.7 3.5 2.6 3.1 2.3 2.8 2.1 1.8 4.0 3.1 3.6 4.7 3.0 2.4 3.0 0.0 2.4 3.8 4.2 4.4 1.2 2.2 2.5 2.1 1.9 2.9 5.0 3.5 3.7 4.4 4.2 1.5 2.2 3.1 2.4 3.7 1.9 3.7 3.3 2.7 4.7 4.9 3.2 3.9 2.8 2.4 10.6 4.5 2.9 2.7 0.8 4.0 3.4 1.7 2.2 5.8 1.9 2.3 3.4 3.2 3.0 4.3 1.2 2.4 3.5 0.2 1.5 3.7 3.7 3.7 2.0 1.8 3.9 2.1 1.5 2.4 1.5 3.1 0.6 1.2 2.8 2.4 1.8 3.1 1.8 2.6 2.1 1.1 2.6 3.4 3.2 0.7 2.4 1.6 1.3 2.2 1.5 1.9 2.7 9.7 3.3 1.8 3.4 2.8 2.8 3.1 2.7 3.5 4.0 6.2 0.0 1.5 9.8 13.2 0.1 0.7 1.1 6.8 5.0 1.6 0.9 2.2 0.0 4.7 1.8 0.0 1.2 6.3 0.9 1.9 1.3 0.7 1.3 4.4 4.9 0.0 3.4 17.7 0.4 1.2 4.3 5.6 1.3 2.5 3.6 0.7 0.6 0.8 5.0 22.6 1.4 4.1 0.6 0.4 0.9 0.6 2.7 0.0 12.2 1.2 3.1 5.2 27.2 19.1 0.7 1.6 1.5 5.8 0.6 0.9 1.5 4.1 3.8 0.0 3.7 4.8 0.8 0.7 3.9 0.1 0.7 9.3 3.3 0.7 0.6 ZNF511-PRAP1 ENSG00000283496 "ZNF511-PRAP1 readthrough" 10 133309410-133352529 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 9.2;kidney: 8.4;liver: 30.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 1.3;RPMI-8226: 1.0" "HPA035360, HPA038713, HPA052451" Supported Uncertain "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA035360: AB_10601931, HPA038713: AB_10673117, HPA052451: AB_2681839" 0.2 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 6.2 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 30.4 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 9.2 0.0 0.1 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.3 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.1 0.1 1.0 0.0 0.1 0.0 0.7 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZNF546 "MGC43537, ZNF49" ENSG00000187187 "Zinc finger protein 546" Q86UE3 19 39984134-40021038 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.5" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Oligodendrocytes: 20.1;Spermatocytes: 57.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030838 Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA030838: AB_10603332" "unprognostic (4.38e-6)" "unprognostic (3.29e-1)" "unprognostic (1.80e-1)" "unprognostic (1.69e-2)" "unprognostic (6.10e-2)" "unprognostic (7.18e-4)" "unprognostic (1.05e-1)" "unprognostic (1.73e-2)" "unprognostic (8.20e-3)" "unprognostic (4.99e-2)" "unprognostic (2.03e-3)" "unprognostic (2.70e-1)" "unprognostic (5.69e-3)" "unprognostic (2.23e-1)" "unprognostic (6.46e-2)" "unprognostic (2.28e-1)" "unprognostic (2.58e-5)" 1.9 2.8 1.1 0.7 1.8 0.5 1.9 1.8 1.5 2.2 1.6 2.1 0.4 1.7 0.9 1.0 2.2 0.5 2.4 1.3 1.0 2.3 3.7 1.3 0.9 1.6 1.3 2.9 1.9 1.2 2.8 0.8 1.8 2.1 0.5 2.4 1.4 1.1 2.5 1.0 1.8 1.4 0.9 3.2 1.5 13.5 1.4 1.0 2.4 1.4 1.1 2.0 1.7 2.8 0.1 2.2 0.8 1.2 1.9 1.1 0.1 0.8 1.2 0.8 1.3 0.1 0.3 1.1 0.9 0.6 0.3 0.0 0.4 0.1 1.3 1.0 1.5 1.4 1.7 0.7 1.0 1.5 0.9 1.1 0.4 0.5 1.3 1.1 1.2 2.0 1.7 2.9 1.0 0.3 0.5 0.3 0.2 0.1 0.2 0.7 0.8 0.5 0.5 0.2 0.5 0.7 0.5 0.0 0.5 0.8 0.3 0.7 0.5 0.3 0.6 0.1 0.5 1.9 2.2 0.2 0.6 0.5 0.4 0.7 0.4 0.8 1.0 0.7 0.7 0.8 0.7 0.6 0.8 0.6 1.3 1.2 0.3 0.8 0.3 0.2 0.9 0.3 1.1 1.8 1.8 1.5 1.3 1.0 1.6 1.3 1.8 0.9 1.4 2.8 3.1 0.0 4.6 7.8 3.9 0.5 1.0 0.8 2.8 8.4 2.4 1.9 6.8 2.8 1.1 3.7 12.5 1.4 4.1 0.6 1.9 1.4 36.0 2.5 4.5 4.0 0.0 1.7 9.9 0.4 0.2 4.9 0.5 1.5 0.0 6.3 4.6 3.0 1.8 1.7 11.7 0.5 2.0 1.9 0.5 7.4 4.4 2.0 0.0 8.4 1.5 4.8 3.1 8.5 20.1 0.3 0.4 4.1 1.9 0.8 2.4 3.5 4.1 7.9 0.0 6.2 2.6 57.8 5.4 1.0 0.0 0.3 2.3 4.8 0.6 0.7 ZNF630 "BC037316, dJ54B20.2, FLJ20573, MGC138344" ENSG00000221994 "Zinc finger protein 630" Q2M218 X 47983356-48071658 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 5.0;Sertoli cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SiHa: 5.3" "Low region specificity" "Detected in all" "HPA001053, HPA068130" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA001053: AB_2666183, HPA068130: AB_2685961" "unprognostic (1.03e-1)" "unprognostic (2.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (8.09e-2)" "unprognostic (5.86e-3)" "unprognostic (5.83e-2)" "unprognostic (9.06e-3)" "unprognostic (8.68e-2)" "unprognostic (5.83e-2)" "unprognostic (2.14e-2)" "unprognostic (7.92e-2)" "unprognostic (6.07e-3)" "unprognostic (5.92e-2)" "unprognostic (1.31e-1)" "unprognostic (3.27e-1)" "unprognostic (7.51e-5)" 1.9 2.2 3.8 1.5 4.0 0.9 2.8 5.0 4.8 3.6 4.1 2.5 1.8 2.6 2.8 2.1 2.6 2.5 2.7 3.6 3.8 2.4 1.4 2.1 1.8 4.0 4.1 4.7 3.2 4.2 2.6 1.6 4.2 3.8 2.5 3.7 2.3 2.8 1.0 1.9 1.8 2.4 3.8 2.3 2.9 0.7 4.2 0.9 3.7 1.2 1.5 3.0 2.7 4.6 1.0 0.7 0.2 0.0 0.1 0.0 0.0 1.4 0.5 1.1 0.6 2.3 4.0 0.1 0.8 1.4 1.6 1.8 0.0 0.8 0.9 0.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 1.0 4.0 2.3 0.0 2.6 0.7 0.0 0.0 4.2 2.5 4.3 0.0 0.0 1.5 3.5 1.2 0.5 1.0 0.0 1.7 2.2 2.3 1.8 5.3 3.7 1.4 3.2 4.3 0.9 1.3 0.0 1.8 1.8 0.0 0.0 3.7 0.0 0.0 0.1 3.3 2.3 0.8 2.0 0.8 0.3 0.9 1.0 0.7 0.7 1.5 0.6 0.9 1.0 0.9 0.7 0.3 0.4 0.5 0.9 3.8 4.0 5.0 4.8 3.6 3.8 4.0 4.1 4.2 3.8 4.2 4.6 0.8 0.0 0.0 2.6 1.4 0.1 1.0 0.8 3.4 2.5 1.6 1.3 1.6 0.0 0.8 1.8 0.0 0.1 0.4 0.9 1.9 1.4 0.0 1.2 1.9 1.2 4.2 0.8 2.2 1.1 0.9 1.4 1.1 1.3 0.0 4.0 1.8 0.3 0.9 0.0 2.6 1.6 0.0 0.0 0.0 0.2 0.3 0.7 0.0 1.0 1.3 0.7 0.0 5.0 3.2 1.0 0.6 0.4 1.0 0.9 1.1 0.7 0.5 1.0 6.6 1.4 1.4 0.2 0.4 1.7 0.3 0.3 1.1 4.0 1.0 0.8 ZNF700 DKFZp434I1610 ENSG00000196757 "Zinc finger protein 700" Q9H0M5 19 11925068-11950773 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA047845 Uncertain Uncertain Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA047845: AB_2680178" "unprognostic (1.92e-1)" "unprognostic (1.20e-2)" "unprognostic (3.99e-1)" "unprognostic (1.97e-1)" "unprognostic (1.51e-1)" "prognostic favorable (1.27e-4)" "unprognostic (8.63e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (2.58e-4)" "unprognostic (9.02e-2)" "unprognostic (7.44e-2)" "prognostic unfavorable (1.75e-4)" "prognostic unfavorable (2.01e-5)" "unprognostic (8.38e-2)" "unprognostic (2.24e-1)" "unprognostic (1.30e-1)" "prognostic favorable (2.53e-5)" 12.1 12.2 4.2 6.5 4.3 17.0 12.4 5.8 5.3 12.7 4.9 15.1 6.1 9.3 8.6 13.7 10.3 4.7 7.7 4.1 4.2 19.4 21.0 13.9 10.4 4.4 4.5 13.9 19.1 7.9 11.2 5.0 4.6 13.8 10.8 9.6 12.2 4.6 5.2 16.6 18.0 4.7 4.2 23.4 14.1 11.3 4.5 8.4 12.3 3.1 11.2 11.6 13.8 4.9 8.0 0.4 8.4 8.7 5.2 5.7 8.5 8.4 7.2 7.4 9.7 6.6 3.9 10.6 7.2 5.4 5.0 6.2 6.9 6.1 10.2 6.0 3.6 11.0 8.2 5.9 4.4 15.6 15.5 4.7 7.1 6.3 7.1 5.0 4.7 6.9 12.4 23.0 10.8 6.5 8.7 14.3 8.6 4.8 7.7 7.3 11.1 8.2 10.5 9.2 4.9 5.9 7.6 5.0 10.1 7.6 8.7 17.7 6.8 18.9 4.9 13.0 9.8 15.9 9.0 10.9 5.0 12.7 6.3 4.8 2.3 4.7 3.2 2.5 3.7 3.2 2.6 4.0 3.2 1.9 2.5 3.2 3.7 3.2 4.4 2.1 3.4 1.9 4.2 4.3 5.8 5.3 4.1 4.2 4.4 4.5 4.6 4.2 4.5 4.9 5.4 9.6 14.1 12.1 7.6 3.1 1.7 2.2 3.4 2.3 5.0 3.9 4.1 8.6 7.4 1.8 2.1 5.2 7.4 9.4 1.9 5.8 0.6 2.2 2.9 5.1 3.0 3.8 15.0 4.5 4.6 2.7 8.2 2.6 16.4 6.5 6.1 7.3 4.5 0.0 13.4 7.7 6.1 7.8 5.0 1.5 4.4 6.8 5.4 30.0 3.9 2.4 9.2 13.0 17.9 5.3 9.7 1.9 3.0 1.9 5.5 2.1 3.7 4.8 0.0 2.6 5.5 11.5 6.8 3.0 1.7 3.7 6.5 3.0 9.1 1.4