Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCB5 "ABCB5alpha, ABCB5beta, EST422562" ENSG00000004846 "ATP binding cassette subfamily B member 5" Q2M3G0 7 20615207-20777038 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "epididymis: 26.4" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.8;Early spermatids: 8.1;Fibroblasts: 2.4" "Cancer enriched" "Detected in some" 9 "melanoma: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SK-MEL-30: 47.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.82e-1)" "unprognostic (1.57e-1)" "unprognostic (2.55e-3)" "unprognostic (1.55e-2)" "unprognostic (1.14e-2)" "unprognostic (2.98e-1)" "unprognostic (2.60e-3)" "unprognostic (1.65e-2)" "unprognostic (2.05e-1)" "unprognostic (2.63e-1)" "unprognostic (6.23e-2)" "unprognostic (5.26e-3)" "unprognostic (3.56e-3)" "unprognostic (9.30e-4)" "unprognostic (1.29e-1)" "unprognostic (1.80e-2)" "unprognostic (2.70e-2)" 2.0 0.0 0.2 0.2 0.2 0.4 2.1 0.4 0.2 1.5 0.2 1.3 0.1 0.6 26.4 0.1 0.2 2.7 0.3 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.1 0.2 0.2 0.5 0.1 0.1 0.3 0.1 0.8 0.4 0.6 0.1 0.0 0.2 0.5 0.2 0.0 0.0 0.1 0.0 0.7 0.5 0.4 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 6.6 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 47.8 0.0 0.0 0.2 0.0 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.4 0.2 0.2 0.2 0.2 0.1 0.2 0.1 0.2 0.4 0.1 0.0 0.5 0.3 0.0 0.5 2.8 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 8.1 0.3 0.2 0.4 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.1 1.3 0.0 0.0 0.0 0.3 0.0 1.7 0.0 0.0 0.0 1.5 1.0 0.6 0.4 1.8 1.9 0.0 0.2 1.0 1.0 0.6 0.0 0.0 0.4 0.0 0.9 0.0 0.1 0.0 0.3 0.0 1.7 0.6 0.6 0.4 0.0 0.6 0.0 0.6 0.0 0.0 0.8 ABTB1 "BPOZ, Btb3, BTBD21, EF1ABP" ENSG00000114626 "Ankyrin repeat and BTB domain containing 1" Q969K4 3 127672935-127680926 "Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 822.3" "Lineage enriched" "Detected in all" 13 "granulocytes: 822.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035022, HPA035023" Uncertain Supported Nucleoli,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol Nucleoli "HPA035022: AB_10669998, HPA035023: AB_10602104" "unprognostic (6.76e-2)" "unprognostic (9.18e-3)" "unprognostic (2.11e-2)" "unprognostic (6.34e-2)" "unprognostic (6.51e-2)" "unprognostic (2.00e-3)" "unprognostic (4.43e-2)" "unprognostic (2.12e-2)" "unprognostic (9.81e-2)" "unprognostic (4.48e-3)" "unprognostic (4.55e-3)" "unprognostic (2.86e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (2.88e-1)" "unprognostic (1.81e-2)" "unprognostic (3.98e-2)" "unprognostic (7.92e-3)" 38.4 18.7 30.6 18.8 35.8 51.1 33.4 38.0 42.4 42.0 28.9 38.9 12.3 29.7 5.3 13.4 37.2 18.1 40.5 32.7 25.9 25.5 17.3 32.0 22.0 28.7 27.2 30.3 17.7 9.0 31.4 12.2 27.1 31.0 4.6 8.7 24.5 13.6 44.7 24.9 31.8 7.6 24.7 89.7 27.5 8.1 29.1 21.5 21.8 26.2 7.4 32.9 31.2 30.7 4.3 10.7 0.9 2.0 10.0 8.7 7.8 6.8 12.2 4.5 6.5 0.3 8.9 1.9 11.9 5.1 6.0 2.2 0.2 5.1 1.0 20.7 2.5 3.1 19.4 2.5 7.5 0.5 9.5 12.0 5.6 4.5 1.5 15.2 4.8 8.3 0.1 13.5 4.9 6.6 4.9 13.4 0.9 4.9 11.7 3.0 5.6 13.8 6.7 3.3 9.5 6.0 4.8 6.6 25.0 2.6 1.4 3.7 9.1 4.8 4.0 8.5 2.3 11.5 3.8 0.6 11.1 4.0 7.8 40.7 64.5 161.8 17.0 48.2 16.6 17.8 19.0 17.1 28.6 21.1 16.6 14.3 822.3 25.2 44.5 18.1 46.3 46.2 30.6 35.8 38.0 42.4 32.7 25.9 28.7 27.2 27.1 24.7 29.1 30.7 45.3 19.2 13.0 10.7 31.7 11.7 15.6 14.2 7.4 10.4 9.9 15.6 8.1 22.8 5.3 7.3 18.8 8.1 34.2 11.3 15.6 15.1 0.5 9.9 11.1 20.8 23.9 58.7 26.1 16.8 22.3 21.0 23.0 10.1 14.7 10.1 27.5 8.9 21.3 3.3 12.2 15.0 12.2 64.7 16.4 1.7 33.8 37.4 10.6 18.7 74.3 18.0 35.0 6.6 12.8 25.9 21.4 22.6 25.2 12.8 26.3 23.0 6.9 31.1 65.7 16.1 36.8 1.0 8.6 4.2 9.2 15.9 38.6 10.6 10.3 11.8 AC004922.1 ENSG00000284292 "Novel protein, ARPC1A and ARPC1B readthrough" 7 99325879-99394653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Club cells: 2.5;Exocrine glandular cells: 1.5;granulocytes: 1.3;Pancreatic endocrine cells: 1.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004334 Uncertain Approved "Cell Junctions,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 11: Alveolar cells - Smell perception" "Cell Junctions" Cytosol "HPA004334: AB_1078215" 1.5 1.2 0.1 0.9 0.1 0.5 1.2 0.1 0.3 1.1 0.0 1.4 0.9 0.9 0.0 1.3 1.0 0.1 1.0 0.2 0.1 1.0 1.2 1.8 0.8 0.5 0.2 0.8 0.9 0.1 0.8 0.2 0.3 0.9 0.0 0.0 1.2 0.0 0.4 0.7 1.9 0.2 0.1 2.9 1.2 0.5 0.2 0.2 1.2 0.0 0.1 1.2 1.0 0.0 1.9 2.1 0.4 0.2 0.3 1.0 2.5 1.6 0.7 0.9 1.0 4.1 3.5 2.5 4.8 1.5 1.7 1.6 0.1 1.1 0.2 1.0 1.7 1.2 1.3 0.9 0.2 1.4 1.4 1.4 0.7 1.3 0.6 0.3 1.0 0.8 1.6 2.2 1.0 5.1 3.8 0.1 0.7 0.7 2.8 1.4 0.3 0.7 0.2 1.0 0.4 0.3 1.3 2.7 6.0 0.3 0.8 0.7 2.0 3.3 1.3 3.6 2.4 0.0 1.0 2.4 1.7 2.5 3.5 11.8 20.7 23.7 8.7 20.4 6.2 9.3 8.5 8.7 16.6 11.1 7.1 6.9 16.9 7.1 18.7 11.2 16.5 31.5 0.1 0.1 0.1 0.3 0.2 0.1 0.5 0.2 0.3 0.1 0.2 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.5 0.5 0.8 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 AC013394.1 ENSG00000279765 "Novel protein" 15 92883413-92949230 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "bone marrow: 383.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 18.5;Breast myoepithelial cells: 17.1;dendritic cells: 13.0;Endometrial ciliated cells: 25.9;Endometrial stromal cells: 20.7;Glandular and luminal cells: 35.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "unprognostic (7.26e-3)" "unprognostic (1.34e-1)" "unprognostic (1.53e-3)" "unprognostic (1.42e-1)" "unprognostic (2.84e-2)" "unprognostic (8.97e-2)" "unprognostic (4.62e-2)" "unprognostic (9.34e-2)" "unprognostic (7.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.12e-2)" "unprognostic (2.33e-2)" "unprognostic (1.46e-6)" "unprognostic (2.74e-1)" "unprognostic (3.13e-1)" "unprognostic (2.94e-2)" "unprognostic (3.12e-2)" 34.6 43.5 56.0 36.4 63.4 383.8 82.9 62.5 79.9 49.6 56.2 47.9 35.7 50.9 47.6 40.9 45.2 47.5 37.1 53.0 57.0 56.5 44.8 68.4 65.3 62.7 58.6 60.3 40.4 41.1 0.5 55.4 61.1 56.4 53.0 68.1 50.9 44.9 27.7 47.9 38.9 39.2 60.2 58.4 40.5 36.2 57.0 68.3 93.9 36.4 58.0 42.3 0.2 75.2 31.1 23.9 88.6 57.1 27.0 35.0 64.8 30.1 53.6 47.0 35.1 24.5 70.6 32.8 29.3 39.0 35.6 47.2 37.7 30.8 46.9 0.2 37.0 57.7 48.6 23.6 56.0 30.9 36.8 37.5 44.6 17.4 88.5 68.2 45.0 43.0 60.4 92.5 52.5 33.2 36.3 47.6 77.4 68.2 20.1 50.8 44.5 71.0 66.5 59.3 46.9 53.4 64.4 46.0 115.0 82.6 106.4 69.5 31.5 35.0 27.0 27.4 66.7 67.1 86.0 70.9 27.2 58.5 41.2 10.0 0.9 2.9 2.2 0.7 2.4 4.7 2.5 2.6 0.9 2.8 3.2 2.6 5.7 2.7 1.4 3.0 3.1 0.6 56.0 63.4 62.5 79.9 53.0 57.0 62.7 58.6 61.1 60.2 57.0 75.2 6.9 6.4 11.2 0.0 3.9 0.0 0.0 0.0 0.0 0.0 18.5 17.1 0.0 0.0 3.7 1.8 0.0 2.1 13.0 0.0 3.9 1.2 0.0 25.9 20.7 3.5 0.0 0.0 0.0 1.4 2.3 3.8 0.0 35.4 3.8 12.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 2.0 3.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 3.0 8.0 8.4 0.0 0.0 AC015802.6 ENSG00000284526 "Novel protein" 17 76563710-76570544 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skeletal muscle: 25.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Alveolar cells type 2: 7.8;Endometrial ciliated cells: 17.7;Endometrial stromal cells: 17.9;Glandular and luminal cells: 12.7;Respiratory ciliated cells: 8.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 58.7;SK-MEL-30: 72.7" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" 3.4 5.0 0.7 4.8 0.9 7.0 1.0 1.0 0.6 1.8 9.9 1.9 4.3 3.5 0.8 6.1 2.7 3.8 8.8 1.8 1.0 2.7 3.0 4.5 4.7 1.5 1.1 4.5 10.9 0.3 0.7 3.6 0.7 2.6 0.3 16.5 10.0 0.5 25.1 16.0 2.9 0.1 0.7 3.9 5.2 15.2 0.9 0.0 5.0 0.1 0.2 2.6 2.5 0.4 14.9 11.7 9.2 20.5 0.0 0.0 12.2 6.5 0.0 0.0 0.0 25.5 11.3 15.7 7.7 0.0 7.2 15.2 0.1 0.8 0.0 4.1 13.1 21.9 9.8 58.7 0.0 20.5 13.6 0.0 1.2 0.0 0.1 13.2 0.0 9.3 18.3 17.3 0.0 20.4 18.1 36.0 16.0 16.7 14.6 10.6 24.9 14.4 0.2 13.7 19.6 24.5 8.7 46.7 72.7 18.6 33.5 17.6 10.1 26.4 18.9 18.3 28.3 22.3 9.4 12.6 15.6 16.1 33.4 1.4 7.3 1.8 11.8 7.5 19.4 9.9 12.7 12.9 6.3 7.4 11.6 12.0 16.9 6.5 4.6 6.1 7.1 8.1 0.7 0.9 1.0 0.6 1.8 1.0 1.5 1.1 0.7 0.7 0.9 0.4 0.3 16.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.4 0.0 0.0 4.3 0.0 0.0 0.0 0.5 0.0 0.0 4.2 0.0 17.7 17.9 0.7 0.0 0.0 0.0 0.2 0.0 1.1 0.0 12.7 1.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.1 8.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.7 2.6 0.0 0.0 AC023055.1 ENSG00000257390 "Novel protein" 12 55757275-55827546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 8.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 6.3;granulocytes: 2.5;Respiratory ciliated cells: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.0" "HPA017653, HPA030902, HPA030903" Uncertain Approved "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 74: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" "Cytoplasmic bodies" "HPA017653: AB_1847799, HPA030902: AB_10669872, HPA030903: AB_10964180" "unprognostic (8.84e-4)" "unprognostic (2.25e-1)" "unprognostic (8.19e-2)" "unprognostic (1.16e-1)" "unprognostic (1.60e-1)" "unprognostic (7.17e-2)" "unprognostic (1.55e-3)" "unprognostic (1.86e-1)" "unprognostic (6.30e-2)" "unprognostic (3.79e-2)" "unprognostic (3.05e-2)" "unprognostic (2.16e-2)" "unprognostic (1.16e-5)" "unprognostic (6.36e-2)" "unprognostic (1.71e-1)" "unprognostic (1.22e-1)" "unprognostic (4.37e-3)" 0.4 0.1 0.0 0.1 0.2 0.5 0.1 0.1 0.2 0.0 0.2 0.1 0.2 0.0 0.3 0.2 0.1 0.4 0.2 0.1 0.1 0.3 0.2 0.1 0.4 0.3 0.2 0.0 0.1 0.3 0.0 0.0 0.3 0.2 0.3 0.9 0.1 0.1 0.2 0.2 0.4 0.0 0.0 0.1 0.2 8.9 0.7 0.0 0.0 0.0 0.2 0.3 0.1 0.3 0.1 0.0 1.2 1.7 1.1 0.0 1.3 0.8 0.6 0.1 0.5 0.5 0.4 1.3 0.2 0.7 0.4 0.7 1.0 1.2 0.5 0.0 1.2 0.9 0.3 0.5 0.5 1.4 1.0 0.2 0.0 0.5 0.2 0.0 0.1 0.7 0.6 0.0 0.2 0.0 0.7 1.0 1.9 1.4 0.0 1.1 1.4 0.8 0.7 0.6 1.6 0.5 0.5 2.1 3.0 0.5 0.4 0.4 0.0 0.0 0.1 0.2 0.3 0.0 1.1 0.9 0.3 0.2 0.2 1.2 0.4 1.4 1.1 0.8 0.7 1.9 1.3 0.7 1.1 1.3 0.9 1.3 0.2 1.8 2.0 0.6 1.8 1.4 0.0 0.2 0.1 0.2 0.1 0.1 0.3 0.2 0.3 0.0 0.7 0.3 0.1 6.4 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.3 2.5 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 AC092143.1 ENSG00000198211 "Novel protein (MC1R-TUBB3 readthrough)" 16 89919165-89936092 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 6.6" "Cell type enriched" "Detected in single" 15 "Fibroblasts: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SK-MEL-30: 10.7" "CAB011512, HPA043640, HPA046280" Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 11: Alveolar cells - Smell perception" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB011512: AB_444319, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.90e-4)" "unprognostic (6.87e-2)" 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 6.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.5 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC093899.2 ENSG00000251569 "Novel protein" 2 169479480-169525922 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "retina: 18.5;testis: 8.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.6;HSkMC: 3.0;LHCN-M2: 5.4;SK-MEL-30: 2.5" HPA046125 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA046125: AB_2679549" 0.6 0.1 0.4 0.1 0.4 0.0 1.6 0.4 1.3 0.7 0.4 0.3 0.1 1.4 1.3 0.3 1.8 1.8 1.4 0.4 0.4 1.0 0.1 0.9 0.3 0.5 0.5 1.2 0.4 1.0 0.5 0.4 0.5 1.7 0.7 18.5 0.4 1.3 2.6 0.2 0.1 1.0 0.4 0.6 0.4 8.8 0.4 0.6 1.8 2.4 0.6 0.8 0.1 0.4 0.0 0.0 1.0 0.1 0.8 4.6 0.0 1.0 0.6 0.9 0.5 0.0 0.0 0.0 0.2 1.1 1.2 0.0 0.7 0.0 1.2 0.2 0.0 0.0 0.0 0.1 0.1 0.5 0.0 3.0 0.5 1.2 0.4 1.1 1.5 0.9 0.3 0.0 5.4 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.7 0.1 0.3 0.0 2.5 0.1 0.2 0.0 0.0 0.7 0.2 0.0 0.2 0.0 0.5 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 1.3 0.4 0.4 0.5 0.5 0.5 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACAD11 FLJ12592 ENSG00000240303 "Acyl-CoA dehydrogenase family member 11" Q709F0 3 132558138-132660082 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 64.4;liver: 103.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 6.4;Erythroid cells: 5.7;Plasma cells: 7.6;Syncytiotrophoblasts: 9.7" "Cancer enhanced" "Detected in single" "renal cancer: 1.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048317 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" "HPA048317: AB_2680354" "unprognostic (5.04e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (3.31e-2)" "unprognostic (3.36e-1)" "unprognostic (2.69e-4)" "unprognostic (1.20e-1)" "unprognostic (2.85e-2)" "unprognostic (2.40e-1)" "unprognostic (5.90e-2)" "unprognostic (5.86e-2)" "unprognostic (5.68e-2)" "unprognostic (1.06e-3)" "unprognostic (6.01e-2)" "unprognostic (1.48e-1)" "unprognostic (2.71e-2)" "unprognostic (2.93e-1)" 16.2 7.6 8.6 2.8 11.3 7.8 6.1 9.3 13.3 8.5 23.3 7.7 17.0 8.0 6.7 4.0 8.5 4.0 15.4 8.8 9.0 64.4 103.6 5.8 3.3 10.2 9.9 9.9 8.2 8.8 9.8 9.8 10.0 6.6 3.4 11.7 5.7 6.0 4.3 6.3 15.8 6.4 9.6 4.3 4.8 8.2 10.3 4.6 6.4 2.0 3.2 5.5 6.5 11.5 5.8 5.2 10.5 13.6 23.2 17.9 10.5 13.6 21.0 8.0 10.5 19.3 2.1 3.9 7.6 7.7 9.0 4.3 8.0 11.9 12.7 6.7 5.6 4.3 5.5 18.1 23.0 4.7 4.1 12.2 8.9 11.0 27.2 18.6 7.9 5.0 2.3 8.2 11.2 7.8 3.0 3.2 6.2 2.8 5.2 3.3 8.4 6.4 18.0 3.8 4.1 6.7 10.5 5.0 28.5 10.9 10.5 3.4 6.5 6.3 3.9 3.6 4.8 6.7 2.3 4.0 8.4 1.6 5.2 0.0 0.2 0.0 0.6 0.4 0.5 0.6 0.6 0.3 0.2 0.6 1.4 0.7 0.0 0.9 0.3 0.9 0.3 0.2 8.6 11.3 9.3 13.3 8.8 9.0 10.2 9.9 10.0 9.6 10.3 11.5 1.4 6.4 3.2 0.0 2.1 0.1 0.2 0.7 2.8 0.9 0.6 0.4 0.0 0.0 0.8 0.0 0.0 4.2 0.8 0.4 0.0 0.8 0.6 1.5 2.0 1.0 4.8 5.7 0.0 1.1 0.9 1.6 0.0 0.8 1.3 1.5 0.4 3.9 0.7 0.0 0.0 0.5 0.0 0.8 0.2 0.2 0.6 0.8 0.0 0.0 2.3 0.6 4.1 0.0 0.0 0.4 0.2 0.7 7.6 0.2 4.4 1.6 1.0 2.9 0.0 0.9 1.1 0.1 0.3 0.9 0.3 9.7 2.2 1.1 0.7 0.1 ACP5 "HPAP, TRAP" ENSG00000102575 "Acid phosphatase 5, tartrate resistant" P13686 19 11574660-11579008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 174.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 426.9;Hofbauer cells: 426.7;Macrophages: 298.2;Proximal tubular cells: 145.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 200.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 41.1;K-562: 30.4;RPMI-8226: 41.4;SK-MEL-30: 127.6;U-138 MG: 102.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002584, HPA057655, HPA059463" Enhanced Uncertain Cytosol "Intracellular and membrane" NA NA 4000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB002584: AB_564039, HPA057655: AB_2683490, HPA059463: AB_2684028" "unprognostic (4.27e-2)" "unprognostic (2.05e-2)" "unprognostic (2.93e-1)" "unprognostic (8.60e-3)" "unprognostic (2.96e-1)" "unprognostic (1.95e-2)" "unprognostic (5.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.13e-2)" "unprognostic (3.80e-1)" "unprognostic (3.66e-3)" "unprognostic (9.09e-2)" "unprognostic (1.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" 9.4 6.0 2.2 42.4 3.9 9.4 25.6 2.5 21.4 34.7 3.0 46.4 31.9 19.2 7.8 23.4 8.6 26.7 5.1 1.9 3.9 74.0 32.5 174.1 87.1 4.1 3.1 20.3 11.9 2.4 1.3 13.3 6.0 19.6 36.4 20.1 14.3 7.0 1.4 24.9 30.2 13.3 4.1 43.5 38.7 4.0 15.7 25.4 3.0 5.0 43.6 33.1 11.3 5.7 10.2 1.1 0.0 0.2 0.5 0.0 41.1 1.1 25.8 0.0 0.1 0.4 0.3 1.4 1.8 9.0 5.9 0.3 0.0 4.5 0.1 12.1 0.8 0.3 0.0 5.0 1.4 0.1 0.6 0.0 4.1 0.4 0.0 0.0 0.0 0.0 30.4 0.2 0.0 2.3 0.9 1.4 0.8 0.3 0.7 0.4 1.8 41.4 0.0 0.4 0.7 1.0 0.0 0.0 127.6 1.1 0.2 0.4 0.9 102.9 1.2 1.8 0.3 0.7 5.7 0.6 23.7 0.1 4.0 0.4 35.3 76.6 15.8 36.1 8.8 200.1 26.0 19.6 7.3 110.9 35.3 20.2 10.4 13.3 36.3 62.5 67.8 36.4 2.2 3.9 2.5 21.4 1.9 3.9 4.1 3.1 6.0 4.1 15.7 5.7 2.2 9.6 7.8 0.0 75.7 10.3 11.0 21.8 25.0 18.3 14.6 18.4 1.4 15.7 5.7 7.3 18.8 33.4 21.2 7.0 9.8 1.8 0.2 0.7 9.1 30.9 3.0 24.5 0.0 11.3 32.7 19.8 10.7 0.9 63.7 0.8 426.9 8.4 426.7 1.7 0.0 4.7 10.2 106.0 68.6 0.7 1.8 298.2 14.2 1.0 79.8 48.5 8.2 0.0 0.1 4.4 20.4 12.0 33.4 14.5 12.7 145.8 2.5 41.4 0.0 0.4 2.8 0.1 0.2 14.6 11.1 26.1 29.5 0.1 6.7 6.1 ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860942-222944639 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 172.1" "Cell type enhanced" "Detected in all" "Horizontal cells: 523.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 410.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: AB_1848344, HPA071021: AB_2686335" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.75e-4)" "prognostic unfavorable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" 25.2 19.8 22.2 17.5 24.7 27.7 90.8 21.9 29.5 18.4 8.8 27.0 22.2 12.6 24.8 36.1 11.0 16.7 14.8 22.9 26.7 24.3 30.9 20.6 12.3 20.9 26.0 10.8 16.7 172.1 10.0 28.0 22.4 66.1 25.5 32.2 45.4 16.2 25.3 14.9 16.0 14.5 27.5 10.5 50.6 23.3 35.3 19.8 23.8 15.2 14.2 33.5 20.6 24.5 49.7 77.0 118.3 121.9 42.1 121.3 35.0 61.0 159.5 70.5 139.8 75.0 126.4 24.0 33.8 51.9 147.2 143.9 20.4 121.3 76.0 44.0 50.1 55.8 52.2 68.0 91.0 36.2 26.6 60.0 180.7 120.0 163.6 34.7 65.6 39.8 109.6 83.1 78.1 104.8 70.4 42.5 59.9 102.9 42.4 40.0 85.4 39.7 80.8 198.2 57.3 49.3 36.0 79.5 410.5 67.5 49.8 64.8 58.0 43.9 76.2 41.5 41.0 30.0 17.2 81.3 40.7 26.0 140.0 10.7 14.0 20.0 18.0 16.0 17.5 10.5 11.2 13.6 15.2 11.1 16.0 14.9 15.6 16.6 17.2 20.8 9.5 17.5 22.2 24.7 21.9 29.5 22.9 26.7 20.9 26.0 22.4 27.5 35.3 24.5 73.1 35.3 70.8 110.4 29.6 46.5 101.8 97.5 55.2 101.9 89.9 62.9 57.2 28.6 93.8 36.8 77.2 43.7 45.0 46.6 7.9 32.7 59.2 68.9 39.6 41.4 20.9 35.8 91.0 31.1 10.7 56.6 81.1 100.7 27.3 25.3 32.2 52.7 37.4 523.3 124.2 36.0 99.7 49.0 62.7 27.1 26.1 75.3 48.0 69.3 32.1 184.7 20.6 149.3 120.1 37.3 41.3 35.7 24.6 109.4 17.5 14.6 80.3 55.6 46.0 52.8 68.2 49.7 45.3 108.6 48.7 60.6 32.4 52.0 50.7 117.1 ADCY1 "AC1, DFNB44" ENSG00000164742 "Adenylate cyclase 1" Q08828 7 45574140-45723116 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, cAMP biosynthesis" "Calmodulin-binding, Lyase" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 33.7;liver: 19.2;retina: 53.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 521.3;Excitatory neurons: 147.2;Inhibitory neurons: 117.9;Rod photoreceptor cells: 174.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 22.2;SH-SY5Y: 25.5;SK-MEL-30: 30.1;WM-115: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018364, HPA068274" Uncertain Approved Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "CAB018364: AB_2223098, HPA068274: " "unprognostic (9.41e-3)" "unprognostic (7.30e-4)" "unprognostic (9.31e-2)" "unprognostic (2.98e-1)" "unprognostic (4.18e-2)" "unprognostic (3.07e-3)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (1.64e-3)" "unprognostic (2.89e-1)" "unprognostic (7.73e-3)" "unprognostic (1.54e-1)" "unprognostic (4.74e-6)" "unprognostic (2.49e-1)" "unprognostic (7.65e-3)" "unprognostic (2.87e-1)" "unprognostic (2.23e-1)" 1.9 1.8 13.7 0.3 22.4 0.0 4.7 15.4 33.7 5.3 0.0 0.4 0.2 1.8 0.5 0.6 2.0 0.6 2.9 31.9 0.0 1.9 19.2 0.6 0.4 1.2 0.9 0.9 3.3 1.9 2.6 0.4 1.1 2.8 0.4 53.0 0.3 1.2 7.7 0.4 0.3 0.9 0.0 1.7 1.1 2.8 4.0 0.3 2.4 8.5 0.3 0.8 1.3 24.5 0.8 5.9 2.1 3.2 4.1 0.1 4.0 0.2 0.0 0.8 0.3 0.6 0.0 0.0 0.2 0.2 5.8 1.9 3.8 0.3 0.1 10.7 2.7 0.0 0.0 0.6 0.0 0.2 0.1 4.9 2.8 0.5 22.2 0.0 0.1 8.6 0.3 7.0 0.3 7.1 0.0 0.0 8.3 5.1 0.0 0.0 0.0 11.7 0.0 5.7 13.4 25.5 2.1 0.0 30.1 3.1 2.0 3.5 0.0 0.6 4.2 0.5 3.6 0.0 0.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 22.4 15.4 33.7 31.9 0.0 1.2 0.9 1.1 0.0 4.0 24.5 3.5 0.0 0.0 30.7 0.3 0.3 0.6 0.0 0.0 43.8 10.6 5.7 11.4 2.8 0.0 0.0 521.3 0.1 0.3 0.5 1.9 0.0 2.9 1.0 23.1 10.8 31.2 0.0 147.2 0.9 0.2 4.2 0.0 0.7 0.0 0.2 15.7 52.3 0.3 42.1 117.9 1.0 2.0 3.2 0.4 0.7 1.8 0.2 3.6 17.8 0.0 13.8 0.0 63.3 4.0 0.5 0.1 7.5 0.1 2.6 0.0 0.4 0.0 174.4 0.0 2.3 8.8 0.5 6.8 0.1 0.1 0.0 0.6 0.6 0.6 0.3 AIP "ARA9, FKBP16, FKBP37, XAP2" ENSG00000110711 "Aryl hydrocarbon receptor interacting protein" O00170 11 67483026-67491103 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cushing syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033674, HPA050217, CAB069477" Approved Supported Cytosol NA NA 13000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB033674: AB_2224981, CAB069477: AB_10002466, HPA050217: AB_2681055" "unprognostic (2.59e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (8.15e-2)" "unprognostic (9.54e-2)" "unprognostic (4.02e-2)" "unprognostic (2.17e-2)" "unprognostic (1.14e-1)" "unprognostic (6.19e-3)" "unprognostic (2.18e-1)" "unprognostic (9.75e-2)" "unprognostic (1.16e-1)" "unprognostic (5.28e-2)" "unprognostic (3.10e-1)" "unprognostic (2.70e-1)" "unprognostic (2.40e-2)" "unprognostic (9.45e-2)" 62.9 58.1 72.5 47.4 77.6 40.4 58.5 74.7 82.4 84.5 66.7 78.4 33.7 71.0 32.4 38.9 66.9 39.4 72.1 70.3 74.3 68.0 51.6 62.3 89.5 75.9 72.7 77.9 48.8 35.4 51.1 33.5 74.6 60.8 20.1 22.9 40.6 36.0 46.4 39.5 64.7 28.8 71.8 85.1 57.0 29.7 73.1 78.7 63.6 45.8 49.1 73.1 62.6 80.4 80.8 91.1 51.6 49.9 64.8 64.2 39.3 49.7 61.2 83.6 60.9 143.7 77.9 142.2 118.1 55.3 63.5 63.9 59.2 51.9 32.1 209.3 63.5 86.5 98.7 87.0 67.1 87.5 145.1 77.8 48.3 74.6 48.4 81.4 43.0 138.6 50.0 83.6 55.5 153.7 187.7 214.6 49.0 122.0 115.7 82.2 78.5 126.5 59.5 47.2 81.4 81.3 64.4 45.5 204.3 19.9 60.9 87.2 71.5 73.4 71.1 108.9 46.3 67.4 99.8 112.7 100.4 67.4 57.7 192.5 117.9 135.6 194.3 144.6 212.0 241.6 227.4 227.6 179.8 221.5 203.4 194.7 78.2 165.3 175.0 207.9 352.4 182.4 72.5 77.6 74.7 82.4 70.3 74.3 75.9 72.7 74.6 71.8 73.1 80.4 57.2 32.1 25.6 6.8 69.4 30.3 35.8 54.2 31.9 36.8 24.6 33.1 23.1 30.0 33.7 49.7 4.2 56.4 61.9 50.1 82.2 46.8 25.3 12.7 31.0 54.0 31.8 22.5 4.0 42.2 63.5 51.0 23.4 18.0 77.3 51.7 45.7 23.3 66.7 37.0 4.9 34.7 48.8 65.0 54.6 14.2 53.1 56.1 56.9 5.6 72.5 49.6 76.2 5.0 10.5 41.2 53.5 35.3 50.2 42.7 86.1 98.3 17.4 29.4 39.5 36.4 86.5 21.7 28.4 19.4 21.2 59.5 90.6 42.0 25.4 52.2 ALX1 CART1 ENSG00000180318 "ALX homeobox 1" Q15699 12 85280220-85301784 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 3.9;kidney: 6.1" "Cell type enriched" "Detected in some" 5 "Melanocytes: 32.0" "Cancer enriched" "Detected in some" 10 "melanoma: 16.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 10.4;HEK 293: 23.3;HUVEC TERT2: 17.2;SK-MEL-30: 29.5;THP-1: 18.0;WM-115: 14.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001598, HPA018905" Uncertain Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies" "Nucleoplasm, Golgi apparatus" "HPA001598: AB_1078400, HPA018905: AB_1844783" "unprognostic (4.92e-3)" "unprognostic (8.09e-2)" "unprognostic (1.09e-3)" "unprognostic (1.84e-1)" "unprognostic (6.24e-2)" "unprognostic (2.05e-2)" "unprognostic (9.27e-2)" "unprognostic (1.22e-1)" "unprognostic (3.57e-1)" "unprognostic (2.01e-1)" "unprognostic (1.55e-5)" "unprognostic (8.97e-2)" "unprognostic (1.43e-1)" 0.2 0.0 0.2 0.0 0.2 0.0 0.2 0.1 0.3 1.0 0.4 0.0 0.0 0.7 3.9 0.0 2.3 0.0 0.0 0.2 0.3 6.1 0.0 0.0 0.0 0.2 0.2 1.6 0.0 0.0 0.7 0.0 0.2 0.1 0.0 0.2 1.9 0.9 0.0 1.6 0.0 0.3 0.2 0.0 0.0 0.8 0.2 0.0 0.0 0.8 0.0 0.4 0.3 0.2 0.0 6.0 0.0 0.0 0.7 0.7 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 3.6 0.0 10.4 0.5 0.0 0.0 23.3 0.0 4.1 0.0 0.3 0.0 0.0 0.0 0.0 3.1 0.0 9.3 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.7 5.8 0.0 0.0 29.5 4.1 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 0.0 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 2.2 0.2 1.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 AMMECR1L MGC4268 ENSG00000144233 "AMMECR1 like" Q6DCA0 2 127861630-127885967 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000590, HPA057234" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Cytosol "HPA000590: AB_2666037, HPA057234: AB_2683376" "unprognostic (1.34e-1)" "unprognostic (1.29e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.92e-1)" "unprognostic (9.10e-2)" "unprognostic (2.66e-2)" "unprognostic (1.19e-2)" "unprognostic (2.70e-1)" "unprognostic (1.11e-1)" "unprognostic (4.98e-2)" "unprognostic (2.27e-2)" "unprognostic (4.06e-3)" "unprognostic (7.75e-2)" "unprognostic (4.54e-1)" "unprognostic (1.12e-2)" "unprognostic (8.91e-2)" 12.4 10.1 3.1 3.4 3.3 2.4 10.9 3.2 3.8 12.1 2.6 9.9 4.5 12.1 2.4 10.0 11.5 5.0 9.4 3.2 3.4 9.2 12.7 8.9 3.7 3.4 3.3 10.8 10.5 8.5 7.2 7.4 3.3 9.7 4.6 2.3 8.9 5.7 8.3 11.4 9.4 7.3 2.9 10.1 9.6 12.7 3.8 5.4 9.0 7.9 5.1 9.4 11.4 3.2 8.0 5.6 16.4 12.3 15.7 12.0 11.1 10.0 14.4 13.6 14.6 15.0 7.4 6.5 6.6 18.2 6.0 7.7 17.2 10.5 17.9 13.1 9.8 5.7 5.4 11.2 18.3 9.7 9.6 15.6 21.9 18.8 18.4 12.6 19.1 9.5 8.3 5.4 14.6 4.7 10.3 2.7 11.3 9.7 14.1 11.0 15.7 4.7 10.1 3.7 11.0 11.9 12.9 16.2 27.0 14.1 7.0 8.6 13.4 16.6 9.0 5.4 8.5 5.6 11.1 7.6 7.7 7.7 12.5 0.5 1.2 3.8 1.5 1.3 2.0 1.4 1.6 1.5 1.7 1.6 1.4 1.1 1.8 1.6 1.6 1.8 1.4 1.3 3.1 3.3 3.2 3.8 3.2 3.4 3.4 3.3 3.3 2.9 3.8 3.2 9.8 19.2 8.1 5.9 7.2 18.0 8.6 4.8 9.6 5.3 14.5 9.7 12.0 10.0 9.2 3.7 6.2 5.9 7.1 8.6 0.0 6.2 11.4 11.8 27.0 10.4 5.4 5.0 10.4 5.8 7.7 11.1 10.2 12.6 7.0 10.2 8.2 16.2 4.6 1.7 9.2 9.4 2.0 7.5 6.6 15.1 6.8 5.8 5.4 8.4 4.4 4.2 3.1 7.5 10.8 9.2 6.7 8.2 12.2 14.8 5.5 4.6 14.7 6.0 0.0 15.4 11.8 6.6 9.8 13.2 15.8 7.7 7.0 6.4 9.3 13.9 ANKRD28 "CFAP79, FAP79, KIAA0379, PITK, PP6-ARS-A, PPP1R65" ENSG00000206560 "Ankyrin repeat domain 28" O15084 3 15667236-15859771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Melanocytes: 282.8;Oligodendrocyte precursor cells: 364.4;Oligodendrocytes: 284.4;Plasma cells: 733.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 27 "basophil: 17.0" "Lineage enriched" "Detected in single" 27 "granulocytes: 17.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (4.72e-2)" "unprognostic (8.71e-2)" "unprognostic (1.91e-3)" "unprognostic (1.48e-2)" "unprognostic (9.73e-2)" "unprognostic (4.29e-3)" "unprognostic (1.38e-1)" "unprognostic (1.27e-1)" "unprognostic (8.04e-2)" "unprognostic (2.04e-1)" "unprognostic (5.39e-3)" "unprognostic (7.71e-2)" "prognostic favorable (2.85e-4)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "unprognostic (4.43e-2)" "unprognostic (1.06e-1)" 13.2 7.0 8.1 5.7 9.1 11.6 13.4 12.3 12.6 11.3 6.8 10.0 9.6 9.0 27.7 7.8 7.6 9.9 5.8 8.1 8.4 10.3 13.5 9.0 5.8 9.5 7.9 11.3 13.8 15.7 5.6 6.4 8.9 6.8 9.7 14.0 8.2 7.8 23.9 10.7 7.8 6.3 7.9 7.1 10.7 11.9 7.5 10.3 13.5 20.1 8.9 9.1 10.1 10.7 16.3 10.7 11.6 7.9 38.4 31.7 37.7 20.6 28.9 26.0 29.8 6.5 16.3 31.6 7.0 20.8 20.4 6.5 9.6 17.0 26.4 6.9 13.5 15.0 14.5 10.7 62.7 23.4 10.0 46.4 11.7 24.6 25.6 32.4 27.5 17.4 11.5 41.4 67.6 11.0 19.7 15.1 23.8 10.8 8.8 17.1 21.8 26.9 24.9 16.2 5.9 10.5 15.3 15.4 63.9 10.4 9.2 18.3 21.8 32.9 20.2 25.1 20.3 25.2 31.2 18.8 24.6 16.8 25.5 17.0 0.0 0.0 0.3 0.0 0.4 0.2 0.6 0.3 0.1 0.2 0.2 0.3 0.1 0.2 0.0 0.3 0.2 0.2 8.1 9.1 12.3 12.6 8.1 8.4 9.5 7.9 8.9 7.9 7.5 10.7 39.2 32.1 51.2 63.6 69.9 42.6 20.8 17.0 17.6 27.9 37.7 16.0 18.9 18.6 39.9 7.3 139.7 8.9 71.6 19.5 9.8 14.4 95.5 25.5 55.0 61.4 19.8 37.6 175.4 20.7 9.3 73.4 36.7 42.0 196.7 17.3 21.0 45.1 41.0 52.2 144.5 18.1 22.4 59.7 181.3 92.2 34.8 87.5 282.8 47.8 16.7 43.2 19.6 364.4 284.4 14.8 14.8 10.9 733.4 35.1 12.7 11.3 45.2 41.3 0.0 45.6 29.3 24.4 10.5 25.3 33.5 3.4 195.5 10.2 20.5 21.5 ANXA5 "ANX5, ENX2" ENSG00000164111 "Annexin A5" P08758 4 121667946-121696995 "Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Blood coagulation, Hemostasis" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1156.8;Extravillous trophoblasts: 1125.1;Syncytiotrophoblasts: 1140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003677, HPA035330" Approved Approved "Nuclear membrane" NA NA 5000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nuclear membrane" "CAB003677: AB_425305, HPA035330: AB_2674574" "unprognostic (1.22e-1)" "unprognostic (1.03e-2)" "unprognostic (9.70e-2)" "prognostic favorable (3.64e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.01e-5)" "prognostic unfavorable (1.64e-5)" "unprognostic (7.33e-3)" "unprognostic (3.09e-1)" "unprognostic (6.04e-2)" "unprognostic (6.49e-3)" "unprognostic (4.54e-1)" "prognostic unfavorable (9.29e-7)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.02e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (1.26e-4)" 490.6 286.5 111.7 241.7 126.3 96.2 314.0 136.9 144.7 429.1 137.7 181.9 96.5 288.7 162.6 135.1 225.0 273.1 213.9 106.4 134.7 216.2 149.5 299.0 136.2 151.2 129.6 224.7 162.9 133.7 176.7 466.0 150.4 211.7 155.5 78.1 273.8 250.5 85.2 132.5 130.9 370.3 134.3 175.7 186.0 110.4 154.3 63.3 182.9 114.8 135.2 298.1 178.6 157.3 463.5 339.6 438.0 256.1 2094.3 1645.5 503.4 1582.7 1464.9 841.3 744.8 246.2 200.6 35.7 282.9 2224.8 581.7 165.4 287.3 727.6 762.2 335.1 171.2 105.0 281.6 647.4 1213.9 221.1 178.3 945.5 344.7 705.1 665.9 927.4 1120.9 25.2 106.0 271.8 2133.5 306.7 225.5 75.1 231.9 417.7 718.5 8.2 1014.5 72.6 1368.9 66.3 117.1 141.4 579.7 227.6 1515.2 872.3 201.5 261.2 830.6 1322.1 632.1 955.2 478.0 240.8 308.6 76.0 847.8 123.5 1586.2 122.2 725.8 359.9 104.8 830.5 136.0 127.3 158.8 131.9 745.6 89.5 51.3 74.6 157.9 48.4 798.0 91.2 289.9 773.3 111.7 126.3 136.9 144.7 106.4 134.7 151.2 129.6 150.4 134.3 154.3 157.3 286.5 243.6 233.9 13.7 85.0 199.3 266.4 395.9 76.2 6.8 101.6 107.4 88.3 265.9 257.2 132.4 25.0 1156.8 53.2 15.6 297.4 703.5 16.2 239.7 318.1 287.7 48.6 29.0 15.4 338.2 1125.1 564.7 91.3 312.6 148.7 177.5 186.4 54.8 753.2 13.5 7.1 110.9 187.2 446.5 705.1 41.4 379.9 544.0 352.2 45.0 412.5 161.4 13.4 23.1 26.8 501.1 31.2 366.3 203.1 473.8 15.3 194.3 268.9 30.0 295.9 443.1 377.2 15.9 28.6 101.1 140.8 1140.8 122.0 185.7 43.2 188.2 AP000350.4 ENSG00000251357 "Novel protein" 22 23862188-23895223 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 38.5;Alveolar cells type 2: 78.1;Club cells: 43.0;Fibroblasts: 25.6;granulocytes: 54.2;Melanocytes: 33.8;Respiratory ciliated cells: 44.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.1;SK-MEL-30: 1.6;THP-1: 1.5" HPA042960 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 11: Alveolar cells - Smell perception" "HPA042960: AB_2678241" 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.2 0.1 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.5 0.4 0.6 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 1.1 1.0 0.0 0.5 1.6 0.1 0.1 1.5 0.0 0.0 0.5 0.4 0.0 0.8 0.0 0.4 0.3 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.5 78.1 0.0 0.2 16.4 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 43.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 54.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.2 0.0 15.5 0.0 0.0 3.3 33.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 44.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 14.5 0.0 9.0 0.0 0.5 0.0 AP1S2 "MRX59, MRXS5, PGS, SIGMA1B" ENSG00000182287 "Adaptor related protein complex 1 subunit sigma 2" P56377 X 15825806-15854931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "epididymis: 663.3" "Cell type enhanced" "Detected in all" "Hofbauer cells: 259.8;Kupffer cells: 392.6;Langerhans cells: 609.2;Macrophages: 362.7;monocytes: 630.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 13.1;glioma: 22.0;melanoma: 49.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 326.8;intermediate monocyte: 325.0;myeloid DC: 221.1;non-classical monocyte: 175.4;plasmacytoid DC: 82.2" "Group enriched" "Detected in all" 5 "dendritic cells: 221.1;monocytes: 326.8" "Cell line enhanced" "Detected in all" "Karpas-707: 298.0;SK-MEL-30: 442.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049894, HPA060945" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Vesicles" "HPA049894: AB_2680939, HPA060945: AB_2684393" "prognostic favorable (9.86e-4)" "unprognostic (4.62e-2)" "unprognostic (2.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (3.85e-1)" "unprognostic (2.03e-3)" "unprognostic (5.76e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.53e-6)" "unprognostic (1.85e-2)" "unprognostic (5.61e-2)" "unprognostic (5.08e-2)" "unprognostic (6.35e-2)" "unprognostic (3.13e-1)" "unprognostic (9.34e-2)" "unprognostic (6.47e-2)" 28.3 21.4 24.6 36.7 28.4 38.3 15.0 32.0 36.9 31.6 27.3 42.1 11.9 52.2 663.3 21.4 13.5 20.1 74.8 25.1 48.0 13.1 15.9 25.8 33.2 42.7 35.8 8.8 7.8 16.7 19.4 42.0 47.0 11.6 22.0 43.7 9.5 30.5 70.1 14.0 20.1 76.3 34.4 43.0 19.5 23.4 29.6 28.7 12.5 93.7 28.8 26.1 12.7 33.8 12.0 14.2 130.1 78.4 29.5 19.1 5.0 47.1 22.7 31.1 41.1 9.6 11.1 22.6 183.0 72.6 50.4 16.1 31.7 10.8 57.0 30.1 64.9 15.3 16.7 14.7 24.2 63.1 16.9 12.2 11.2 36.0 33.1 50.4 78.1 19.1 14.3 298.0 72.4 8.7 12.9 39.5 171.0 6.4 42.5 29.5 116.7 50.6 37.4 2.5 14.8 69.2 18.4 4.8 442.2 84.1 52.7 69.2 43.9 67.8 21.2 92.5 41.9 25.5 58.7 37.3 33.6 28.0 159.7 50.9 326.8 34.6 21.1 325.0 24.8 30.8 25.5 20.6 221.1 28.0 18.5 18.1 52.8 27.9 175.4 82.2 38.1 228.0 24.6 28.4 32.0 36.9 25.1 48.0 42.7 35.8 47.0 34.4 29.6 33.8 130.8 3.2 13.1 37.2 77.0 55.2 12.7 9.1 8.6 34.7 12.0 11.4 195.6 12.8 3.2 9.2 12.5 5.3 114.2 9.2 33.2 13.7 5.1 50.4 32.6 166.3 26.9 32.6 15.1 6.4 18.9 38.0 7.7 78.0 78.6 15.6 147.4 8.6 259.8 11.8 73.2 8.4 12.2 392.6 609.2 17.5 17.4 362.7 149.4 31.9 630.0 21.1 62.8 19.1 85.0 10.3 14.0 7.2 26.0 19.0 6.5 9.0 1.6 39.3 39.5 26.7 39.1 55.7 28.8 10.6 51.6 5.6 58.3 4.0 8.5 6.7 AP5B1 "AP-5, DKFZp761E198, PP1030" ENSG00000254470 "Adaptor related protein complex 5 subunit beta 1" Q2VPB7 11 65773898-65780976 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "bone marrow: 44.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "neutrophil: 25.0" "Lineage enriched" "Detected in many" 14 "granulocytes: 25.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065739, HPA067880" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "Golgi apparatus" "HPA065739: AB_2685550, HPA067880: AB_2685914" "unprognostic (3.64e-1)" "unprognostic (9.40e-2)" "unprognostic (4.37e-3)" "unprognostic (1.45e-2)" "unprognostic (5.56e-3)" "unprognostic (1.09e-2)" "unprognostic (1.29e-2)" "unprognostic (3.26e-2)" "unprognostic (1.73e-1)" "unprognostic (1.62e-2)" "unprognostic (1.25e-1)" "unprognostic (2.15e-1)" "prognostic favorable (2.31e-5)" "unprognostic (2.03e-2)" "unprognostic (2.15e-2)" "unprognostic (2.45e-1)" "unprognostic (1.67e-1)" 8.3 4.8 3.2 6.9 2.6 44.0 6.6 5.8 3.6 5.4 1.3 6.0 5.7 7.1 2.0 10.2 5.2 3.1 5.0 3.6 1.2 5.7 5.8 8.7 4.7 3.9 1.5 2.9 10.3 6.4 3.5 3.8 3.0 5.0 3.0 2.5 7.0 4.5 9.6 9.1 6.8 3.2 1.1 10.0 6.0 2.5 1.8 4.8 4.9 3.4 4.3 6.6 5.1 1.6 12.8 9.8 2.8 14.3 8.6 4.1 16.4 5.3 6.2 6.1 4.7 7.7 6.0 7.8 9.4 6.3 12.4 15.8 8.7 4.3 2.9 12.1 10.1 7.0 12.0 3.8 5.8 9.9 13.3 7.0 10.1 4.0 2.9 6.0 5.2 13.6 15.6 9.7 3.6 9.2 5.5 10.5 4.6 4.4 10.1 17.3 0.5 16.8 5.9 15.8 2.7 5.4 4.1 2.6 26.0 3.7 4.4 14.1 7.6 10.2 8.6 13.6 6.0 10.0 11.2 8.1 7.5 8.5 10.5 1.1 1.7 0.6 0.5 1.0 0.2 0.3 0.2 0.2 0.5 0.3 0.3 0.2 25.0 0.4 1.3 0.3 0.2 0.8 3.2 2.6 5.8 3.6 3.6 1.2 3.9 1.5 3.0 1.1 1.8 1.6 2.0 0.0 8.8 6.2 3.9 2.4 12.3 4.3 7.4 5.0 4.2 2.0 1.6 2.8 3.7 7.3 14.6 7.6 5.9 12.8 1.9 8.9 1.4 6.3 2.9 3.0 3.0 0.0 3.6 13.6 18.2 2.9 6.6 10.7 2.5 5.3 1.4 7.1 14.0 11.8 3.2 3.8 6.1 12.4 2.1 0.7 0.6 11.6 7.2 3.7 17.8 3.0 6.2 1.0 2.2 9.4 6.9 3.8 3.6 5.6 10.1 8.8 2.9 8.0 0.0 3.7 3.0 0.6 4.7 6.0 2.3 34.9 4.3 2.0 4.5 10.0 APOC4 ENSG00000267467 "Apolipoprotein C4" P55056 19 44942237-44945496 "Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 208 "liver: 629.1" "Cell type enriched" "Detected in single" 37 "Hepatocytes: 3.8" "Cancer enriched" "Detected in single" 15 "liver cancer: 0.7" "Region enhanced" "Detected in single" "white matter: 3.0" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 2.4;TIME: 1.2" "Not detected" "Not detected" HPA062671 Approved "Secreted to blood" NA NA 1000000000 980000000 "Cluster 6: Non-specific - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA062671: AB_2684828" "unprognostic (1.82e-3)" 0.2 0.3 0.4 0.0 0.8 0.5 0.2 0.5 0.9 0.0 0.0 0.1 0.0 0.4 0.7 0.0 0.2 0.3 0.2 0.2 0.5 0.0 629.1 0.2 0.1 0.5 0.4 0.3 0.0 0.2 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.4 0.1 1.2 0.5 0.0 0.0 0.0 0.1 0.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.2 0.1 0.5 0.3 2.4 0.0 0.3 0.0 1.2 0.1 0.0 0.1 0.0 0.1 0.3 0.4 0.0 0.4 0.0 0.6 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.0 0.1 0.1 0.4 0.0 0.0 0.4 0.8 0.5 0.9 0.2 0.5 0.5 0.4 0.4 0.3 0.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 ARAP1 CENTD2 ENSG00000186635 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1" Q96P48 11 72685069-72793599 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020703, HPA070383" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 36000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "CAB020703: , HPA070383: AB_2686262" "unprognostic (3.60e-2)" "unprognostic (7.68e-2)" "unprognostic (6.19e-2)" "unprognostic (5.98e-2)" "unprognostic (5.76e-2)" "unprognostic (1.64e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (4.01e-2)" "unprognostic (4.07e-1)" "unprognostic (5.95e-2)" "prognostic favorable (2.04e-5)" "unprognostic (1.84e-1)" "unprognostic (1.05e-3)" "unprognostic (6.93e-2)" "unprognostic (2.57e-2)" "prognostic favorable (6.41e-4)" "unprognostic (7.56e-3)" 41.5 63.5 40.0 58.6 48.6 97.5 33.4 37.9 50.4 44.1 62.9 35.5 29.6 38.9 14.0 37.7 48.3 44.2 42.9 42.2 38.5 47.8 40.2 71.8 53.4 50.6 42.3 49.4 37.1 20.4 48.9 35.5 45.9 44.9 18.2 8.6 33.3 25.7 20.1 47.1 43.3 28.7 40.1 117.5 31.3 16.4 50.8 32.2 46.6 20.1 25.2 39.7 37.5 56.8 19.7 41.9 15.2 18.5 63.4 42.9 23.1 26.2 46.5 29.8 29.3 56.0 50.8 42.9 51.3 44.4 40.7 64.5 23.2 64.4 12.5 50.9 28.4 36.6 40.3 81.9 43.7 25.1 98.7 47.5 65.4 48.7 23.4 36.2 33.2 31.3 31.5 17.4 13.9 40.3 38.9 89.3 9.5 35.1 25.9 36.8 23.2 21.3 27.5 61.1 15.7 32.0 19.1 27.9 84.8 19.5 25.1 56.8 37.5 41.0 28.5 42.8 16.4 27.4 14.3 23.0 21.8 37.4 22.3 19.3 24.8 30.7 8.9 39.4 5.2 6.6 5.9 6.8 15.9 4.7 4.5 5.4 50.8 13.4 51.3 5.3 6.7 17.6 40.0 48.6 37.9 50.4 42.2 38.5 50.6 42.3 45.9 40.1 50.8 56.8 8.9 28.9 32.3 33.6 16.1 7.4 7.5 14.3 15.4 4.3 8.7 7.9 2.6 7.2 9.0 16.5 33.3 9.2 18.3 16.5 9.8 13.5 50.1 14.1 11.7 7.8 23.3 9.9 7.7 7.5 8.9 22.4 16.3 9.1 10.8 36.9 9.7 10.8 43.0 0.0 7.0 12.8 12.2 45.6 25.1 6.4 20.8 57.3 8.8 30.0 29.0 7.4 21.6 17.6 31.5 12.1 10.9 15.1 12.3 4.8 20.9 5.3 20.2 2.8 0.0 8.6 8.8 0.4 2.8 10.8 5.4 4.9 12.4 10.5 15.1 7.4 ARHGEF2 "GEF-H1, GEFH1, KIAA0651, Lfc, LFP40, P40" ENSG00000116584 "Rho/Rac guanine nucleotide exchange factor 2" Q92974 1 155946851-156007070 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Mitosis, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043437 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 3: Monocytes - Immune response regulation" "HPA043437: AB_2678481" "unprognostic (2.27e-2)" "unprognostic (8.30e-3)" "unprognostic (3.24e-3)" "unprognostic (1.90e-3)" "unprognostic (4.14e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (9.20e-6)" "unprognostic (5.96e-2)" "unprognostic (2.14e-1)" "unprognostic (3.62e-2)" "unprognostic (2.59e-1)" "unprognostic (3.92e-1)" "prognostic unfavorable (7.17e-6)" "unprognostic (4.63e-2)" "unprognostic (2.70e-1)" "unprognostic (8.85e-3)" "unprognostic (7.98e-2)" 48.9 12.3 52.6 39.2 80.8 64.0 40.8 69.0 77.8 38.8 18.7 47.3 18.8 37.0 15.2 25.8 42.1 31.1 42.8 55.5 56.2 35.7 13.2 89.9 48.4 85.9 75.9 28.1 15.1 18.5 16.8 32.1 84.1 27.3 28.8 11.1 25.0 15.1 17.8 17.9 45.4 29.9 60.9 69.9 39.9 33.9 77.2 38.6 46.7 16.8 32.6 37.8 31.4 130.6 32.0 25.7 44.0 30.3 41.4 51.9 45.3 69.9 89.4 67.2 71.5 23.3 23.6 79.4 41.9 53.8 35.4 45.7 26.7 22.2 50.9 32.5 22.9 105.1 40.9 14.0 162.4 138.6 87.8 61.1 90.4 100.2 122.1 50.7 55.7 60.5 59.2 94.2 96.2 17.7 70.2 187.2 48.8 53.4 17.0 75.5 61.3 135.9 28.3 19.0 72.1 33.1 30.1 43.6 246.1 43.6 45.0 188.7 73.6 57.7 32.7 50.9 89.8 155.7 171.1 55.6 82.4 68.7 144.6 15.1 20.6 17.1 15.7 18.1 10.8 14.6 9.9 11.3 18.2 13.1 9.6 11.0 31.7 11.0 21.9 8.7 9.9 28.2 52.6 80.8 69.0 77.8 55.5 56.2 85.9 75.9 84.1 60.9 77.2 130.6 26.4 38.5 73.4 2.9 43.9 15.2 28.1 12.6 10.8 54.1 15.7 12.3 6.2 10.0 12.0 16.5 2.1 3.5 32.1 21.1 7.9 15.5 52.9 6.6 10.2 32.3 30.5 48.6 30.8 5.3 22.8 24.8 59.1 13.3 27.9 8.9 23.2 1.0 29.7 1.7 17.0 20.9 16.2 49.0 67.8 16.1 11.5 46.0 24.9 20.6 82.9 12.9 48.4 22.1 105.5 16.5 22.5 10.1 20.0 16.7 9.8 2.2 13.0 3.3 59.2 32.9 30.8 3.1 4.1 11.7 13.8 3.4 29.7 2.1 14.2 40.2 ARMC9 "ARM, FLJ12584, KIAA1868, KU-MEL-1" ENSG00000135931 "Armadillo repeat containing 9" Q7Z3E5 2 231198546-231376848 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 48.6;retina: 71.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 310.6;Excitatory neurons: 112.5;monocytes: 116.4;Rod photoreceptor cells: 202.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 15.5" "Immune cell enhanced" "Detected in some" "NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 275.2;SK-MEL-30: 222.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019041, HPA026671" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA019041: AB_1845035, HPA026671: AB_1845036" "unprognostic (2.90e-1)" "unprognostic (2.86e-1)" "unprognostic (5.35e-2)" "unprognostic (6.26e-2)" "unprognostic (1.99e-2)" "unprognostic (5.57e-2)" "unprognostic (7.20e-4)" "unprognostic (1.58e-2)" "unprognostic (4.85e-2)" "unprognostic (7.17e-3)" "unprognostic (4.14e-1)" "unprognostic (9.15e-2)" "unprognostic (7.43e-2)" "unprognostic (1.30e-2)" "unprognostic (4.19e-2)" "unprognostic (5.57e-2)" "prognostic unfavorable (7.66e-5)" 2.3 15.0 4.0 5.4 5.3 1.9 3.3 1.1 15.5 5.6 48.6 14.7 1.7 19.5 5.6 4.2 8.7 7.7 2.3 5.9 1.9 5.2 0.8 7.1 1.6 0.4 2.4 9.4 3.7 10.8 11.1 5.7 0.1 5.5 5.2 71.5 3.2 6.6 1.0 2.6 6.5 23.5 0.0 1.1 8.9 9.4 0.2 3.0 7.6 1.1 2.1 6.8 2.7 1.7 21.2 10.8 20.3 15.1 14.5 23.7 8.3 23.3 275.2 28.6 35.8 3.1 10.3 2.7 11.0 68.3 46.6 12.2 24.8 22.7 25.0 1.7 15.2 1.5 14.0 11.6 41.3 5.0 5.1 63.8 8.8 38.3 13.7 73.3 21.7 12.2 4.7 0.6 46.0 29.9 6.3 6.9 44.4 7.7 12.0 7.8 18.2 0.3 30.6 6.9 15.6 32.2 9.3 25.2 222.7 17.8 9.7 5.4 22.6 17.6 10.9 10.0 10.4 24.8 6.2 1.3 33.9 1.0 17.7 1.1 0.2 0.3 0.2 0.1 0.1 0.6 0.2 0.3 0.2 0.3 0.3 0.3 0.5 2.6 0.2 0.3 0.2 0.2 4.0 5.3 1.1 15.5 5.9 1.9 0.4 2.4 0.1 0.0 0.2 1.7 1.3 3.2 36.1 25.8 1.4 1.8 5.6 6.8 1.2 24.0 5.1 5.7 3.3 2.8 7.5 3.7 310.6 4.8 0.1 4.0 1.9 7.3 69.5 25.1 22.3 4.9 7.8 1.3 112.5 17.3 3.0 7.2 3.6 4.1 3.8 6.6 2.5 1.0 10.6 1.7 62.7 6.0 0.0 0.3 2.4 23.8 14.0 6.6 19.6 17.8 116.4 16.7 1.0 25.6 14.1 11.5 1.8 21.4 1.1 1.9 0.7 5.1 31.3 202.4 6.6 5.3 6.4 36.7 15.7 0.6 0.9 2.2 1.3 6.3 10.0 2.1 ARPC1B "ARC41, p40-ARC, p41-ARC" ENSG00000130429 "Actin related protein 2/3 complex subunit 1B" O15143 7 99374249-99394816 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 317.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 948.7;Hofbauer cells: 1088.1;Kupffer cells: 1035.5;monocytes: 1029.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 899.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004832 Enhanced Supported Vesicles,Cytosol NA NA 13000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 51: Myeloid cells - Hemostasis" "Vesicles, Cytosol" "HPA004832: AB_1845044" "unprognostic (5.94e-2)" "unprognostic (2.40e-2)" "unprognostic (2.84e-3)" "unprognostic (2.47e-2)" "unprognostic (1.43e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (2.57e-4)" "unprognostic (4.37e-2)" "unprognostic (7.76e-2)" "unprognostic (1.02e-2)" "unprognostic (1.56e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.62e-6)" "unprognostic (1.18e-1)" "unprognostic (1.87e-2)" "unprognostic (1.24e-1)" "unprognostic (7.27e-2)" 132.2 71.6 19.6 173.3 20.4 209.8 99.1 20.5 25.9 71.7 23.9 104.4 106.6 71.0 14.2 51.6 73.9 48.9 70.1 18.2 21.7 84.4 81.7 169.5 202.1 28.9 23.5 30.1 51.4 14.3 52.4 66.4 26.8 67.4 32.5 1.1 72.4 30.1 18.6 43.2 160.2 39.4 27.3 317.3 66.2 20.4 33.3 62.2 90.1 19.5 95.5 85.1 57.5 28.4 124.3 219.3 16.1 47.5 62.9 225.0 167.9 165.8 170.5 68.7 60.5 146.3 477.8 215.4 308.2 188.5 146.9 93.1 22.4 152.5 27.5 175.5 59.9 157.0 61.6 98.4 179.7 159.5 515.8 125.7 77.3 96.2 94.3 134.6 181.5 113.3 177.9 508.0 100.2 574.5 158.8 332.5 59.6 148.9 435.5 139.5 14.6 536.2 141.2 59.7 13.2 42.1 116.4 506.3 899.5 54.4 119.7 322.4 262.0 190.1 155.8 339.0 216.6 91.4 190.1 263.5 189.9 411.0 350.4 1026.1 2400.1 1973.2 770.3 2458.8 723.9 786.7 883.0 857.2 2054.4 699.1 510.2 680.0 1963.4 633.5 2382.6 1172.9 1315.9 4198.2 19.6 20.4 20.5 25.9 18.2 21.7 28.9 23.5 26.8 27.3 33.3 28.4 182.2 41.7 86.6 1.0 279.2 60.5 141.3 587.9 58.1 9.6 50.8 34.3 9.1 107.2 260.2 130.6 8.4 588.4 416.3 264.9 25.4 407.1 3.2 37.7 37.2 265.5 112.7 84.9 3.2 414.5 948.7 99.7 62.7 41.3 192.2 31.0 226.3 54.5 1088.1 1.7 2.3 97.6 203.4 1035.5 422.8 8.4 37.3 789.1 179.7 28.1 1029.7 21.4 498.5 0.5 1.6 405.1 268.7 18.0 154.0 132.4 516.0 110.9 214.0 14.7 92.1 29.5 238.5 2.7 15.5 26.3 37.1 303.2 324.4 20.4 161.1 187.6 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 573.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 777.0;Hofbauer cells: 921.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 392.8;SK-MEL-30: 590.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 214.3 71.9 50.1 51.6 51.5 107.7 95.8 62.1 50.8 98.5 62.6 84.3 54.7 55.8 131.5 73.2 70.4 99.1 573.9 49.9 66.2 204.0 60.9 190.3 65.9 66.0 59.4 50.1 49.6 117.8 83.6 121.5 69.0 84.3 87.0 79.5 66.6 77.9 66.0 52.6 56.8 61.7 66.3 85.4 61.2 18.2 59.1 26.0 325.5 70.7 57.7 112.8 54.8 102.2 48.1 66.4 25.9 63.3 392.8 46.0 39.2 48.2 67.3 23.0 41.0 35.4 66.1 30.2 60.3 54.5 159.1 62.6 15.0 25.3 28.4 22.9 38.9 134.4 46.7 96.7 107.5 27.7 140.7 100.2 86.5 33.6 22.9 53.2 6.2 50.6 24.3 61.7 67.9 46.0 15.5 48.3 30.3 105.2 40.5 19.4 25.5 41.4 112.0 273.0 40.4 55.0 43.8 145.2 590.5 35.6 47.9 31.3 43.6 30.3 43.1 55.8 23.7 75.5 184.3 22.0 89.5 61.3 24.6 285.2 455.4 318.7 47.6 676.4 43.1 83.9 35.5 36.1 175.1 65.9 40.8 37.9 627.6 60.5 731.4 33.0 43.7 407.2 50.1 51.5 62.1 50.8 49.9 66.2 66.0 59.4 69.0 66.3 59.1 102.2 98.5 317.3 405.0 36.9 92.8 58.6 83.3 103.7 35.3 97.5 105.6 87.8 777.0 100.1 280.9 450.6 45.9 177.4 67.6 83.4 60.7 150.6 2.8 85.7 51.5 79.7 98.1 106.3 49.8 104.1 65.2 122.0 43.3 133.8 257.0 49.3 134.6 50.6 921.2 77.4 53.2 99.3 201.4 564.3 89.9 6.0 88.6 524.6 318.4 56.2 259.2 532.6 53.5 49.8 49.0 64.7 125.5 105.7 87.4 87.8 77.6 304.2 147.3 88.0 177.5 74.5 157.0 14.0 63.6 84.9 64.2 148.2 61.3 53.4 89.7 139.9 ATOX1 HAH1 ENSG00000177556 "Antioxidant 1 copper chaperone" O00244 5 151742316-151772532 "Predicted intracellular proteins" "Copper transport, Ion transport, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 932.7;Proximal tubular cells: 1449.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055036 Approved "Nucleoplasm,Plasma membrane" NA NA 790000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Plasma membrane" "HPA055036: " "unprognostic (5.55e-2)" "unprognostic (1.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.82e-1)" "unprognostic (8.11e-2)" "unprognostic (3.34e-2)" "unprognostic (2.33e-1)" "unprognostic (8.60e-2)" "unprognostic (3.58e-2)" "unprognostic (2.53e-2)" "prognostic favorable (9.57e-4)" "unprognostic (2.72e-1)" "unprognostic (7.15e-2)" "unprognostic (8.18e-2)" "unprognostic (2.57e-2)" "unprognostic (1.87e-1)" "unprognostic (2.22e-1)" 102.0 136.9 173.3 65.9 183.6 73.8 100.1 180.8 201.1 84.4 181.9 84.7 81.8 73.7 98.0 112.1 64.6 63.6 107.4 170.0 189.7 217.1 260.9 80.3 142.9 181.9 184.7 57.8 57.1 180.6 81.2 69.8 183.6 100.2 64.3 24.9 93.0 74.6 53.6 102.8 83.0 75.9 184.9 124.4 76.1 72.9 185.6 82.6 119.3 39.5 128.2 91.7 84.2 192.8 112.0 181.9 104.4 73.1 275.1 224.2 136.6 197.7 225.8 197.2 267.3 248.2 235.8 224.9 233.3 345.7 437.1 102.4 129.2 502.5 161.3 143.9 220.3 98.7 118.4 255.1 254.1 137.5 108.5 291.3 105.0 246.0 161.1 144.7 295.3 138.5 83.4 642.7 305.1 276.6 102.3 304.0 59.8 249.8 382.3 61.4 120.0 350.0 190.6 98.1 136.2 80.0 169.3 476.6 763.4 117.2 234.2 165.3 328.5 201.0 159.4 246.9 345.9 522.6 513.4 136.2 271.7 92.3 846.1 154.6 207.9 199.4 75.1 247.6 69.0 98.6 67.3 66.2 171.3 68.3 53.0 58.0 155.3 97.0 177.2 217.8 103.5 117.3 173.3 183.6 180.8 201.1 170.0 189.7 181.9 184.7 183.6 184.9 185.6 192.8 209.1 57.7 56.6 8.1 93.2 67.7 79.8 204.5 70.0 22.7 250.1 246.5 112.1 165.8 102.2 211.5 14.6 146.0 65.6 213.6 541.9 207.6 178.9 121.1 171.1 183.2 150.7 104.1 6.4 159.1 218.7 127.3 96.8 135.3 73.0 117.8 236.7 932.7 671.2 25.2 9.1 171.1 164.8 221.4 166.0 321.1 83.0 230.4 238.3 4.7 436.7 185.7 88.6 5.5 22.7 318.1 238.7 103.4 170.4 124.2 727.0 1449.1 108.5 24.9 92.1 69.0 235.2 81.9 156.0 153.1 106.4 118.8 55.4 96.6 152.7 122.2 ATP1A1 ENSG00000163399 "ATPase Na+/K+ transporting subunit alpha 1" P05023 1 116372668-116410261 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Mental retardation, Neurodegeneration, Neuropathy, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1482.3" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 1879.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 2979.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018702, CAB069993" Enhanced NA NA 420000 "Cluster 35: T-regs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "CAB018702: AB_626713, CAB069993: AB_2060979" "unprognostic (6.18e-2)" "unprognostic (2.18e-1)" "unprognostic (6.91e-2)" "unprognostic (1.42e-2)" "unprognostic (6.80e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.80e-1)" "unprognostic (1.21e-2)" "unprognostic (6.32e-2)" "unprognostic (1.61e-2)" "unprognostic (1.65e-1)" "prognostic favorable (8.98e-8)" "unprognostic (4.75e-2)" "unprognostic (1.17e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (4.01e-4)" 150.9 206.6 115.5 144.1 135.7 104.3 220.2 176.4 264.7 137.6 209.2 580.5 785.5 92.3 304.6 255.9 143.6 361.3 233.1 176.0 133.9 1127.5 132.5 255.7 89.7 140.8 103.5 137.7 661.3 1482.3 160.6 120.0 196.3 176.4 542.6 301.2 721.9 294.1 147.3 316.6 813.9 146.1 117.4 78.1 201.5 140.0 104.1 92.8 744.4 117.7 132.4 149.7 187.4 142.2 399.8 144.8 147.2 74.5 288.8 277.5 750.8 232.9 462.9 281.6 396.6 583.9 278.5 314.2 321.3 279.0 284.4 505.1 293.8 493.7 406.2 116.1 324.2 183.5 249.2 498.4 220.1 465.2 246.1 311.6 808.0 328.4 429.0 395.5 350.8 187.4 306.9 294.2 253.0 793.7 189.6 167.7 346.0 630.5 285.6 179.7 343.4 278.6 1023.2 405.1 143.8 126.7 363.0 679.6 2979.2 358.2 179.1 265.9 311.9 159.4 221.4 415.4 479.5 140.7 118.1 238.0 488.2 263.1 956.1 19.2 36.6 17.2 59.7 56.6 62.8 26.4 66.9 64.2 59.6 15.2 76.5 55.5 4.5 30.8 86.0 30.4 57.6 53.6 115.5 135.7 176.4 264.7 176.0 133.9 140.8 103.5 196.3 117.4 104.1 142.2 199.2 275.7 295.3 26.8 84.6 276.8 336.8 220.5 390.9 101.0 189.2 145.2 74.1 579.0 238.4 770.6 398.2 83.7 89.1 789.9 373.7 625.6 31.2 205.4 54.3 201.6 176.4 89.2 130.5 315.6 160.6 141.6 134.6 372.1 43.8 212.6 144.2 71.2 129.8 102.6 123.9 353.4 463.9 98.8 254.2 19.3 117.8 145.5 208.1 36.5 56.9 556.8 64.9 77.9 60.9 187.6 307.8 100.8 73.2 271.6 1879.9 308.2 171.6 147.7 32.9 109.8 147.4 20.2 35.8 320.7 268.9 67.6 133.3 58.3 498.6 280.6 ATP5F1E ATP5E ENSG00000124172 "ATP synthase F1 subunit epsilon" P56381 20 59025475-59032345 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 3414.2;Hofbauer cells: 2765.4;Proximal tubular cells: 4125.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.73e-1)" "unprognostic (6.30e-2)" "unprognostic (8.16e-2)" "unprognostic (9.04e-2)" "unprognostic (2.16e-1)" "unprognostic (1.92e-3)" "unprognostic (7.88e-3)" "unprognostic (2.51e-1)" "unprognostic (5.01e-2)" "unprognostic (6.41e-2)" "unprognostic (4.35e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (3.98e-1)" "unprognostic (3.21e-1)" "unprognostic (1.67e-1)" "unprognostic (2.44e-2)" 81.4 88.3 92.2 98.5 94.5 125.6 62.3 95.3 135.8 49.3 95.7 77.2 80.1 51.2 25.3 77.0 45.2 13.9 162.8 92.7 95.7 128.5 80.2 69.3 69.8 94.2 94.0 42.1 44.9 52.9 104.8 34.0 94.4 50.6 33.1 42.8 62.7 23.7 240.1 42.8 78.9 25.6 95.4 93.5 69.5 47.7 93.7 64.7 64.1 107.0 40.0 63.4 55.5 97.1 150.0 49.6 98.1 90.0 94.0 87.2 65.2 155.9 60.6 102.2 66.0 156.3 143.5 81.1 184.7 82.7 159.6 141.5 70.3 123.7 67.0 66.7 76.4 271.4 107.2 136.5 86.4 193.2 234.6 95.0 105.3 62.5 77.8 99.8 76.9 107.6 103.6 113.8 59.4 144.4 247.8 299.1 32.9 220.4 203.4 120.2 138.3 156.8 107.5 83.0 98.0 146.6 261.6 273.9 328.4 83.5 182.5 312.8 264.3 208.3 222.0 138.9 213.7 180.2 245.9 238.1 201.5 117.9 117.1 613.1 420.6 757.3 237.5 463.8 224.9 351.4 285.8 268.7 356.0 291.7 227.8 259.4 713.9 243.1 470.7 601.7 393.3 781.7 92.2 94.5 95.3 135.8 92.7 95.7 94.2 94.0 94.4 95.4 93.7 97.1 1036.3 516.0 530.8 0.0 331.5 0.0 0.0 0.0 0.0 0.0 1042.4 1138.3 0.0 0.0 289.7 1121.9 0.0 705.8 812.6 0.0 3414.2 998.0 0.0 1145.2 1007.1 436.6 0.0 0.0 0.0 1202.6 956.9 341.7 0.0 1410.3 352.0 594.0 0.0 0.0 2765.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 998.4 0.0 0.0 1473.1 0.0 0.0 0.0 0.0 1427.7 0.0 0.0 132.5 0.0 0.0 4125.3 392.8 0.0 0.0 0.0 334.0 0.0 0.0 0.0 0.0 590.5 431.2 731.9 0.0 0.0 ATP6V1B2 "ATP6B2, HO57, VATB, Vma2, VPP3" ENSG00000147416 "ATPase H+ transporting V1 subunit B2" P21281 8 20197381-20226819 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 256.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1130.7" "Group enriched" "Detected in all" 10 "dendritic cells: 336.8;granulocytes: 1130.7;monocytes: 682.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 317.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008147 Enhanced Supported Vesicles NA NA 310000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA008147: AB_1845195" "unprognostic (1.90e-1)" "unprognostic (7.24e-3)" "unprognostic (3.62e-2)" "unprognostic (2.57e-1)" "unprognostic (2.84e-2)" "unprognostic (5.59e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (4.68e-2)" "unprognostic (4.23e-3)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "prognostic favorable (8.41e-4)" "unprognostic (2.41e-1)" "unprognostic (2.09e-2)" "unprognostic (2.47e-2)" "unprognostic (5.25e-2)" 46.4 76.4 112.6 71.9 111.2 45.7 35.3 72.8 126.0 30.1 72.5 38.0 43.9 29.4 31.0 51.3 32.8 39.0 38.2 124.0 135.5 145.8 49.2 72.7 54.1 103.4 120.0 27.5 34.5 71.4 74.5 50.5 138.2 28.1 43.0 205.7 40.4 27.0 66.7 62.5 57.8 40.1 74.8 66.1 32.8 67.8 100.3 50.2 33.4 64.7 48.9 44.5 36.1 99.5 44.2 71.5 87.4 29.2 117.7 72.3 79.1 96.6 61.5 121.5 125.2 81.7 25.4 77.7 38.4 93.1 123.7 36.8 70.1 64.6 129.0 32.9 47.2 54.2 29.9 63.6 137.6 39.0 108.0 65.0 57.9 76.0 69.3 134.1 77.2 101.2 82.0 72.8 132.5 25.0 114.6 46.2 65.6 64.6 31.5 46.6 113.4 40.8 112.9 68.2 68.0 97.9 46.9 62.7 317.9 72.4 81.6 70.7 82.8 61.1 46.3 101.9 78.5 29.4 42.7 90.9 84.6 91.6 158.4 183.7 682.0 485.9 52.9 618.6 57.7 50.2 54.1 56.8 336.8 44.5 54.4 53.7 1130.7 50.8 576.1 82.7 73.0 622.6 112.6 111.2 72.8 126.0 124.0 135.5 103.4 120.0 138.2 74.8 100.3 99.5 16.6 25.6 20.7 20.5 28.1 58.0 28.4 52.1 33.0 106.1 18.5 15.6 17.6 25.8 28.8 29.5 102.2 109.2 38.9 23.3 80.3 43.2 40.8 20.2 13.6 24.1 74.4 35.8 64.3 38.5 56.4 38.8 25.0 35.9 22.2 22.3 25.7 34.7 178.5 190.1 68.0 21.4 36.7 185.2 178.7 24.4 19.6 167.6 104.9 30.0 169.1 51.5 20.6 27.6 29.0 45.2 19.7 28.2 20.7 17.4 75.0 256.7 18.0 137.8 13.1 29.3 34.2 121.6 55.3 43.3 71.6 124.6 27.1 23.1 24.7 20.1 ATP6V1E1 "ATP6E, ATP6E2, ATP6V1E, P31, Vma4" ENSG00000131100 "ATPase H+ transporting V1 subunit E1" P36543 22 17592136-17628749 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 461.8;Proximal tubular cells: 411.3;Syncytiotrophoblasts: 479.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009528, CAB018699, HPA029196" Enhanced Approved Nucleoplasm NA NA 34000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB009528: AB_2062678, CAB018699: AB_781534, HPA029196: AB_2672944" "unprognostic (1.53e-3)" "unprognostic (5.78e-3)" "unprognostic (1.31e-2)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.17e-1)" "unprognostic (2.09e-1)" "unprognostic (3.37e-2)" "unprognostic (7.72e-3)" "prognostic favorable (4.18e-4)" "prognostic favorable (7.66e-8)" "unprognostic (3.81e-2)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (2.75e-1)" 119.5 165.0 209.8 68.3 220.9 90.4 109.5 214.3 287.3 101.7 200.4 128.9 56.6 112.2 135.8 117.2 96.0 84.7 224.9 231.8 226.9 230.5 85.6 110.3 88.6 220.3 202.3 81.9 59.5 239.9 117.1 113.8 230.8 95.0 99.7 128.4 83.7 126.4 232.8 120.3 83.1 121.0 215.9 99.0 101.8 67.3 218.1 108.2 100.8 178.6 109.5 114.5 97.6 245.6 121.8 108.6 96.4 94.3 314.4 169.6 106.0 159.3 212.0 198.7 228.0 137.3 97.5 76.1 132.8 215.0 251.8 187.9 152.8 140.2 174.9 145.9 173.3 137.1 97.5 182.7 459.9 159.8 226.5 212.9 267.7 192.4 138.7 220.9 170.2 95.0 174.8 150.3 341.9 127.4 136.5 114.5 71.0 269.6 152.6 80.3 140.7 45.7 331.6 189.0 70.3 122.7 146.0 101.0 358.9 187.0 98.6 180.4 146.3 137.5 72.6 174.0 119.2 145.7 275.5 96.3 221.2 76.7 189.3 178.1 106.3 184.7 64.0 100.9 63.0 78.7 64.7 61.5 83.6 59.8 60.8 63.7 137.6 76.0 120.5 81.2 97.7 112.8 209.8 220.9 214.3 287.3 231.8 226.9 220.3 202.3 230.8 215.9 218.1 245.6 66.5 76.9 83.4 13.4 47.1 41.9 77.6 121.8 19.9 54.6 33.9 34.8 126.8 74.4 83.9 138.0 27.1 235.1 63.8 105.2 461.8 143.8 7.6 74.3 56.9 69.3 41.9 49.4 24.9 119.7 143.9 60.8 40.8 79.2 90.5 41.6 72.5 46.8 186.8 53.8 24.4 54.0 116.0 75.1 52.1 17.9 94.1 91.9 80.0 15.0 144.1 94.1 85.5 13.0 31.9 154.7 104.7 97.8 38.3 60.1 65.4 411.3 78.8 50.4 59.2 39.0 74.5 71.7 74.7 34.3 51.6 479.1 54.6 57.6 40.1 93.1 ATP6V1G1 "ATP6G, ATP6G1, ATP6GL, ATP6J, DKFZp547P234, Vma10" ENSG00000136888 "ATPase H+ transporting V1 subunit G1" O75348 9 114587706-114598915 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004615, HPA042898" Supported Approved Nucleoplasm,Nucleoli NA NA 96000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoli Nucleoplasm "CAB004615: AB_2258908, HPA042898: AB_2678217" "unprognostic (3.85e-1)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (1.84e-3)" "unprognostic (2.49e-1)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (3.47e-3)" "unprognostic (9.40e-3)" "unprognostic (4.13e-2)" "prognostic favorable (1.73e-7)" "unprognostic (2.44e-2)" "unprognostic (1.50e-1)" "unprognostic (9.11e-2)" "unprognostic (3.92e-2)" 79.5 140.2 70.5 80.5 71.1 131.4 108.4 74.0 101.1 85.0 85.0 70.5 59.4 92.4 177.3 132.5 71.3 64.6 93.0 72.1 79.4 138.1 125.9 84.9 115.4 75.4 79.1 106.2 72.5 172.9 135.1 91.2 80.2 132.7 65.5 91.2 111.9 55.1 124.0 98.1 69.2 60.6 71.5 93.9 121.1 75.4 75.6 104.2 99.2 113.0 100.8 106.8 94.0 75.4 83.6 71.0 153.2 38.8 111.0 84.5 148.3 125.2 86.6 88.5 63.4 92.3 94.8 74.2 106.8 80.0 183.2 179.0 105.6 84.6 79.3 63.2 73.8 72.3 84.4 143.4 156.8 173.1 135.1 105.2 227.9 72.7 87.3 104.1 91.0 123.1 136.0 164.4 131.6 159.0 164.6 113.6 187.0 222.2 126.8 159.0 95.0 126.7 195.2 128.4 113.8 156.3 159.7 284.0 487.6 143.9 235.0 202.5 118.9 80.1 68.9 132.3 142.0 213.6 474.5 139.6 106.8 97.2 112.0 490.1 327.8 495.0 212.6 331.2 264.9 549.6 288.8 255.8 255.0 501.7 374.7 305.5 405.4 255.4 348.4 401.5 398.9 756.7 70.5 71.1 74.0 101.1 72.1 79.4 75.4 79.1 80.2 71.5 75.6 75.4 230.6 160.3 176.6 19.6 353.9 519.0 492.9 1068.9 277.7 170.5 470.4 494.1 151.6 163.0 629.7 331.1 41.7 346.1 268.2 198.5 970.5 374.1 85.7 381.6 223.8 227.7 360.7 157.6 35.0 263.6 336.5 247.0 231.4 594.9 267.4 156.8 219.2 337.1 548.1 164.9 37.4 346.8 1133.2 350.1 517.8 60.3 306.0 382.4 494.5 20.6 699.7 360.9 261.6 20.1 22.9 430.5 218.1 250.9 255.0 686.5 176.7 1021.5 426.3 158.6 236.7 155.6 393.0 400.6 326.7 361.4 576.7 757.4 304.0 280.3 201.6 852.2 AZIN2 "ADC, KIAA1945, ODC-p, ODC1L, ODCp" ENSG00000142920 "Antizyme inhibitor 2" Q96A70 1 33081104-33123492 "Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 32.1" "Group enriched" "Detected in many" 6 "Early spermatids: 233.2;Late spermatids: 855.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 6.4;plasmacytoid DC: 18.9" "Group enriched" "Detected in many" 8 "dendritic cells: 18.9;granulocytes: 6.4" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 11.0;SK-MEL-30: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028527 Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA028527: AB_10602077" "unprognostic (5.33e-2)" "unprognostic (1.60e-1)" "unprognostic (2.16e-3)" "unprognostic (7.50e-2)" "unprognostic (8.28e-2)" "unprognostic (4.56e-2)" "unprognostic (1.15e-4)" "unprognostic (9.19e-3)" "unprognostic (3.89e-2)" "unprognostic (1.54e-2)" "unprognostic (1.06e-3)" "unprognostic (2.16e-1)" "unprognostic (3.18e-1)" "unprognostic (6.91e-2)" "unprognostic (2.91e-1)" "unprognostic (9.45e-2)" "unprognostic (2.41e-1)" 1.4 3.8 7.1 0.8 8.4 0.1 2.1 8.4 9.4 3.8 5.4 3.5 0.4 2.4 1.1 0.9 4.3 1.9 3.6 7.5 7.3 2.7 0.7 1.3 1.0 8.3 7.8 6.3 1.6 3.3 3.5 0.5 8.0 2.2 1.1 3.0 2.2 1.7 1.0 1.4 1.3 1.4 9.8 1.1 1.0 32.1 7.6 1.1 2.5 1.9 1.2 1.4 2.1 12.9 0.5 0.0 1.8 0.3 0.9 3.0 0.2 0.6 1.8 1.3 1.1 0.0 1.5 0.0 0.8 0.5 1.0 0.2 0.9 0.2 0.7 0.0 0.0 0.4 0.0 0.0 3.6 0.0 1.6 3.5 2.0 1.5 1.3 11.0 0.3 0.3 0.0 0.1 1.4 0.0 0.2 0.4 0.8 0.3 0.0 0.2 2.1 0.1 2.1 0.2 0.2 1.3 0.5 0.0 14.0 1.2 0.0 0.3 0.1 0.0 0.8 1.1 0.2 0.8 0.0 0.0 3.2 0.0 0.6 6.4 0.0 0.0 1.4 0.0 1.3 0.1 1.6 1.4 0.0 0.0 1.6 1.6 0.1 0.0 0.0 18.9 0.0 0.8 7.1 8.4 8.4 9.4 7.5 7.3 8.3 7.8 8.0 9.8 7.6 12.9 2.6 0.0 3.0 24.2 2.3 0.0 2.9 0.0 2.8 6.5 3.8 5.2 1.0 0.0 0.6 1.8 18.8 0.5 11.4 10.8 0.0 1.7 233.2 1.7 1.5 2.6 1.2 0.0 45.4 1.4 0.4 4.8 7.7 0.3 0.0 2.0 1.8 0.1 1.2 6.7 27.3 1.4 0.0 0.6 0.0 855.9 6.2 2.8 0.0 44.0 1.7 12.2 0.0 23.6 86.0 1.5 5.2 7.5 1.0 1.5 0.8 3.1 2.2 7.9 6.6 2.9 2.7 22.2 5.8 0.5 0.0 0.3 3.3 2.1 3.3 1.0 B4GAT1 "B3GN-T1, B3GNT1, B3GNT6, BETA3GNTI, iGAT, iGNT" ENSG00000174684 "Beta-1,4-glucuronyltransferase 1" O43505 11 66345374-66347629 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 220.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.3;Horizontal cells: 158.2;Muller glia cells: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015484 Uncertain "Intracellular and membrane" NA NA 57000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "HPA015484: AB_1845235" "unprognostic (1.80e-1)" "unprognostic (7.20e-2)" "unprognostic (1.70e-1)" "unprognostic (3.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.45e-1)" "unprognostic (9.23e-2)" "unprognostic (1.59e-1)" "unprognostic (2.65e-2)" "unprognostic (3.43e-3)" "prognostic favorable (3.55e-5)" "unprognostic (2.20e-1)" "unprognostic (3.50e-1)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-1)" "unprognostic (2.76e-3)" 16.6 41.4 120.6 6.1 124.9 1.3 16.0 71.0 125.2 23.1 68.7 30.1 16.2 28.5 15.2 8.3 23.4 9.9 44.6 115.3 220.2 25.3 18.8 17.3 6.7 85.9 97.3 34.3 25.5 22.6 62.3 22.5 101.0 17.3 7.7 46.0 15.8 22.4 27.7 12.1 14.6 14.0 91.9 10.2 25.8 8.2 150.4 6.5 21.0 19.2 4.3 20.2 16.3 83.9 10.8 26.7 29.7 36.5 32.6 29.3 39.4 18.4 42.5 28.1 22.9 20.1 14.9 8.9 76.1 16.9 24.1 16.8 32.0 20.6 13.5 17.6 58.2 1.3 20.4 77.6 19.3 7.0 2.7 28.6 15.6 17.5 7.4 92.8 33.5 14.8 8.6 13.7 13.6 18.1 16.7 19.1 20.2 10.6 28.0 24.0 23.2 15.9 29.6 2.7 17.8 33.7 15.8 10.4 74.8 18.4 42.6 6.8 19.7 21.8 15.9 28.0 9.6 26.1 19.2 5.3 36.8 5.8 26.0 0.0 1.2 0.0 7.1 0.4 9.9 5.7 7.8 7.6 3.0 3.2 9.0 8.3 0.4 4.6 0.3 7.4 5.7 4.4 120.6 124.9 71.0 125.2 115.3 220.2 85.9 97.3 101.0 91.9 150.4 83.9 13.5 22.4 10.8 25.8 2.9 0.0 1.6 0.0 14.2 72.3 6.2 12.7 45.9 25.8 1.8 20.2 58.4 57.8 8.6 8.0 5.9 7.4 0.5 3.9 9.7 17.1 4.9 0.8 22.1 6.0 22.6 23.4 6.6 2.6 1.3 22.5 30.4 24.4 12.7 158.2 35.0 8.0 0.0 2.4 0.0 2.4 32.6 2.6 0.0 10.3 1.3 70.1 2.1 22.6 14.2 4.3 4.9 40.6 6.1 2.0 13.3 17.5 2.9 47.4 26.3 21.2 11.8 1.4 2.8 5.8 0.0 18.1 2.6 28.0 7.2 0.3 BAIAP2L2 "FLJ22582, pinkbar" ENSG00000128298 "BAR/IMD domain containing adaptor protein 2 like 2" Q6UXY1 22 38084652-38111015 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 98.6;kidney: 42.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 68.2;Intestinal goblet cells: 58.4;Oligodendrocytes: 31.0;Paneth cells: 32.6;Proximal enterocytes: 125.8;Undifferentiated cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 14.1;OE19: 44.2;RPTEC TERT1: 27.3;SK-MEL-30: 38.4;WM-115: 29.8" "Region enhanced" "Detected in many" "olfactory bulb: 3.7" "Low region specificity" "Detected in many" HPA003043 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "HPA003043: AB_2227864" "unprognostic (2.15e-1)" "unprognostic (4.23e-2)" "unprognostic (9.82e-2)" "unprognostic (5.91e-2)" "unprognostic (7.75e-2)" "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (1.37e-3)" "unprognostic (2.30e-2)" "unprognostic (2.14e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-3)" "unprognostic (1.77e-1)" "unprognostic (5.73e-2)" "unprognostic (1.27e-1)" "unprognostic (4.23e-2)" "unprognostic (4.51e-2)" 2.5 1.1 3.1 2.8 3.0 0.1 1.8 2.6 6.1 3.7 2.8 41.0 98.6 2.1 0.4 9.7 1.9 14.9 0.8 3.1 2.6 42.5 3.7 0.9 0.3 2.8 2.8 1.5 2.7 0.1 3.5 0.2 2.9 2.5 12.7 0.4 1.9 0.3 1.2 2.4 81.6 0.8 2.6 1.4 8.5 5.9 2.7 0.6 3.1 0.1 0.4 1.2 3.4 3.7 0.2 12.3 0.0 0.0 0.3 1.9 1.5 3.0 0.0 0.0 0.2 9.6 0.8 0.2 4.6 2.7 0.0 1.6 0.0 0.4 0.0 0.3 0.4 0.9 0.0 14.1 0.6 0.0 0.8 0.3 0.7 7.0 0.5 0.0 0.0 0.5 0.4 0.0 0.1 0.1 0.6 0.3 1.1 44.2 0.0 0.4 0.0 0.8 27.3 0.1 0.2 0.2 0.0 5.3 38.4 0.1 0.3 0.2 0.1 0.1 0.4 0.0 0.0 0.9 0.1 0.2 0.0 0.0 29.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 3.0 2.6 6.1 3.1 2.6 2.8 2.8 2.9 2.6 2.7 3.7 0.2 0.0 0.0 7.8 0.5 0.8 0.2 1.0 1.2 2.8 0.3 0.3 1.1 17.2 0.2 0.0 2.1 0.3 0.2 68.2 1.9 0.6 0.7 2.2 3.8 0.3 27.6 0.0 17.2 0.0 1.2 0.8 21.9 12.8 0.0 0.5 0.4 0.9 0.5 6.7 13.1 58.4 0.0 0.3 0.2 0.5 1.2 0.2 5.4 5.6 0.1 0.2 1.0 7.5 31.0 5.4 32.6 1.2 0.3 0.2 125.8 19.1 0.1 1.4 0.0 0.2 1.3 1.3 4.4 1.4 1.1 0.4 0.5 0.3 41.4 0.5 BAMBI NMA ENSG00000095739 "BMP and activin membrane bound inhibitor" Q13145 10 28677510-28682932 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 81.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 174.7;Breast myoepithelial cells: 163.2;Granulosa cells: 334.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 166.7;SK-MEL-30: 199.0;SuSa: 357.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010819, HPA010866" Approved Approved "Nucleoli fibrillar center,Vesicles,Lipid droplets" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nucleoli fibrillar center, Lipid droplets" "HPA010819: AB_2668371, HPA010866: AB_10601686" "unprognostic (7.02e-3)" "unprognostic (4.52e-2)" "unprognostic (1.28e-2)" "unprognostic (3.17e-3)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (9.42e-6)" "unprognostic (1.09e-1)" "unprognostic (6.45e-3)" "unprognostic (1.05e-1)" "unprognostic (2.03e-3)" "unprognostic (9.29e-2)" "prognostic favorable (5.25e-4)" "unprognostic (1.01e-1)" "unprognostic (3.24e-1)" "unprognostic (2.38e-2)" "unprognostic (2.10e-2)" 4.4 44.1 13.8 2.3 16.3 6.0 23.7 18.4 17.6 5.7 20.7 3.8 1.6 17.9 2.9 2.1 6.3 5.4 43.5 13.6 15.9 19.9 23.9 12.0 2.0 19.9 16.9 81.6 6.9 8.2 8.5 39.3 21.1 7.4 4.7 13.4 6.4 16.7 1.8 5.4 2.1 12.2 16.6 18.0 3.8 8.7 14.8 0.4 1.2 1.9 1.4 30.0 5.4 22.7 1.0 41.0 4.2 2.2 4.8 0.1 24.5 9.7 3.5 15.4 10.0 166.7 17.3 0.5 5.7 7.4 8.8 12.2 10.2 1.6 7.2 10.1 21.0 39.5 6.2 63.7 5.9 2.4 51.5 3.7 2.3 10.4 1.6 96.7 2.4 2.1 22.1 18.7 3.1 70.1 0.2 3.3 71.6 34.5 9.9 0.3 7.8 3.6 12.9 40.4 6.8 5.2 13.2 78.5 199.0 357.8 23.2 3.0 0.3 10.4 7.3 17.0 4.7 0.5 15.0 0.0 1.0 8.9 67.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 16.3 18.4 17.6 13.6 15.9 19.9 16.9 21.1 16.6 14.8 22.7 6.6 9.6 5.9 15.0 5.7 4.0 7.6 0.6 13.1 14.3 174.7 163.2 34.9 58.6 3.5 11.0 4.2 12.0 9.3 33.8 1.9 20.8 0.1 14.3 15.3 7.3 26.8 0.0 0.5 0.2 22.2 46.1 58.6 21.1 1.3 334.8 14.6 16.0 6.7 6.7 0.2 3.8 0.0 1.6 4.2 1.2 3.4 5.4 16.0 15.9 0.7 50.2 0.0 46.3 21.2 12.1 34.6 2.2 4.3 10.8 1.1 16.1 1.4 5.9 0.0 4.2 42.7 1.9 15.5 13.5 1.3 8.5 7.8 6.2 3.8 14.1 BBS5 DKFZp762I194 ENSG00000163093 "Bardet-Biedl syndrome 5" Q8N3I7 2 169479480-169506655 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 70.9;Early spermatids: 213.4;Endometrial ciliated cells: 49.1;Rod photoreceptor cells: 63.4;Spermatocytes: 62.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 17.3" "Low region specificity" "Detected in all" HPA046125 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA046125: AB_2679549" "unprognostic (4.37e-2)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" "unprognostic (1.89e-2)" "unprognostic (1.21e-2)" "unprognostic (4.85e-2)" "unprognostic (1.81e-1)" "unprognostic (5.83e-2)" "unprognostic (2.35e-1)" "unprognostic (2.78e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.55e-1)" "unprognostic (2.62e-2)" "unprognostic (1.25e-1)" "unprognostic (8.67e-2)" "unprognostic (8.83e-2)" "unprognostic (1.67e-1)" 4.2 5.5 5.9 2.8 6.2 1.4 3.5 4.9 6.0 4.4 9.5 4.4 2.6 4.3 3.8 2.6 7.8 3.1 5.2 6.7 6.3 4.2 2.1 2.9 2.1 6.3 7.1 4.8 3.2 7.2 7.9 2.2 6.2 4.2 1.3 11.3 2.7 4.2 7.1 3.9 2.0 2.9 5.9 2.5 3.3 8.6 6.1 1.5 6.1 3.2 1.0 4.4 2.9 5.3 1.0 2.8 3.2 5.2 8.0 6.4 3.2 7.2 2.3 8.4 3.6 2.0 2.0 0.1 3.3 3.5 5.6 3.1 2.4 1.2 3.2 4.9 0.9 1.8 1.2 4.0 8.0 3.9 4.3 7.1 7.3 5.9 1.5 3.9 2.9 5.0 6.7 0.0 2.5 4.0 6.5 4.0 2.7 0.7 3.6 0.0 0.7 0.0 4.6 3.0 3.0 5.4 4.9 3.7 17.3 1.1 3.7 4.3 2.9 11.8 5.6 9.5 6.6 4.5 6.8 0.1 7.0 2.5 7.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.2 4.9 6.0 6.7 6.3 6.3 7.1 6.2 5.9 6.1 5.3 3.7 0.0 5.1 18.9 0.7 1.3 1.2 1.2 2.8 17.1 3.4 4.2 5.1 1.5 3.5 11.0 70.9 0.8 0.3 0.3 0.0 2.1 213.4 49.1 10.7 2.5 2.4 0.4 38.0 1.5 0.5 4.9 0.5 5.8 0.0 3.2 1.1 0.7 1.4 10.1 34.1 1.7 4.1 4.5 0.4 38.4 5.0 2.0 7.2 14.0 0.1 12.2 0.0 17.6 19.0 1.1 0.5 6.0 1.7 0.7 0.4 2.1 15.1 63.4 0.0 5.5 4.2 62.3 7.8 0.9 1.7 0.3 1.1 7.8 1.0 0.4 BCL2A1 "ACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1, GRS, HBPA1" ENSG00000140379 "BCL2 related protein A1" Q16548 15 79960892-79971196 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 617.3" "Group enriched" "Detected in many" 5 "B-cells: 177.4;granulocytes: 220.7;Hofbauer cells: 214.9;Langerhans cells: 508.2;Macrophages: 604.2;monocytes: 386.0" "Cancer enhanced" "Detected in all" "melanoma: 39.4" "Group enriched" "Detected in all" 4 "cerebral cortex: 39.7;pons: 12.5" "Group enriched" "Detected in all" 5 "eosinophil: 284.0;intermediate monocyte: 195.8;neutrophil: 534.0;non-classical monocyte: 378.9" "Group enriched" "Detected in all" 7 "granulocytes: 534.0;monocytes: 378.9" "Cell line enriched" "Detected in many" 5 "SK-MEL-30: 525.0" "Low region specificity" "Detected in single" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "unprognostic (3.19e-3)" "unprognostic (2.61e-1)" "unprognostic (3.99e-2)" "unprognostic (3.54e-3)" "unprognostic (9.65e-3)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-1)" "unprognostic (1.78e-2)" "unprognostic (4.01e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (4.61e-2)" "unprognostic (8.96e-2)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" 28.6 1.7 2.5 105.1 2.7 617.3 4.3 2.8 39.7 4.3 4.3 5.9 4.6 2.8 1.5 2.4 8.4 17.4 4.6 2.4 2.7 3.4 14.7 59.0 72.0 4.9 3.9 0.9 4.7 0.9 1.3 20.4 12.5 2.3 5.9 0.6 4.4 0.9 0.9 1.7 8.0 13.5 3.4 57.9 5.6 0.4 6.3 17.2 2.4 10.8 56.7 52.1 1.7 5.8 0.4 1.4 0.0 0.1 0.6 0.9 0.0 0.0 6.9 0.0 0.6 0.0 0.1 3.0 0.2 0.0 0.2 0.0 0.0 14.3 4.1 1.5 0.0 0.6 0.0 1.4 2.2 3.7 111.4 2.0 0.1 8.2 0.0 0.2 0.7 0.6 0.0 0.4 0.2 0.0 0.1 19.3 0.1 0.0 3.5 0.2 0.1 0.2 0.6 0.1 0.0 0.1 0.0 0.0 525.0 0.0 0.0 5.0 0.0 51.8 4.9 0.2 1.1 0.5 0.3 4.3 2.3 40.3 27.4 24.2 42.3 284.0 24.5 195.8 13.9 64.4 31.3 32.4 25.2 44.2 38.1 35.1 534.0 21.5 378.9 5.0 8.0 49.1 2.5 2.7 2.8 39.7 2.4 2.7 4.9 3.9 12.5 3.4 6.3 5.8 7.6 22.4 57.3 0.0 177.4 11.0 0.8 50.9 0.6 0.1 2.9 3.7 4.3 0.0 38.0 1.8 0.0 1.9 33.9 0.3 1.9 2.2 1.3 12.0 4.2 6.2 0.0 1.3 0.1 1.6 2.3 8.4 2.0 41.1 220.7 0.2 1.4 1.6 214.9 0.0 0.1 0.1 2.0 60.5 508.2 1.5 0.0 604.2 33.8 0.0 386.0 0.3 13.4 0.0 0.0 6.5 0.1 0.0 14.6 1.4 0.1 0.8 13.8 0.2 0.0 1.3 4.8 0.3 0.2 0.5 10.2 4.5 53.3 0.1 0.2 1.8 BEST1 "BEST, BMD, RP50, VMD2" ENSG00000167995 "Bestrophin 1" O76090 11 61950063-61965515 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.3;brain: 41.7" "Cell type enhanced" "Detected in many" "Langerhans cells: 272.8" "Group enriched" "Detected in some" 6 "glioma: 2.0;melanoma: 6.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 37.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 37.6" "Cell line enriched" "Detected in many" 4 "SK-MEL-30: 71.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057464 Enhanced NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 11: Alveolar cells - Smell perception" "HPA057464: AB_2683444" "unprognostic (2.41e-3)" "unprognostic (3.67e-2)" "unprognostic (5.91e-3)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (1.07e-3)" "unprognostic (2.06e-1)" "unprognostic (4.27e-10)" "unprognostic (1.38e-1)" "unprognostic (4.93e-2)" "unprognostic (3.59e-3)" "unprognostic (2.72e-3)" 9.1 3.7 16.3 8.3 30.5 26.3 5.3 24.9 23.2 5.3 10.2 3.8 1.7 4.1 10.0 2.8 5.9 5.1 5.7 16.5 20.2 3.7 2.6 10.3 2.3 27.9 27.3 4.6 2.5 0.3 3.4 2.4 26.7 4.0 1.0 6.7 2.2 2.0 1.6 2.7 3.9 1.8 19.2 11.0 3.3 5.4 28.6 0.4 2.7 1.4 0.4 5.3 4.7 41.7 0.8 0.8 0.4 0.7 17.7 3.8 1.4 1.0 1.8 0.4 1.3 0.5 0.5 0.1 1.7 1.1 2.0 1.1 0.0 0.0 0.3 0.3 0.2 0.0 6.7 0.9 4.9 0.2 0.5 5.6 1.6 1.9 4.1 1.8 0.0 0.8 0.8 7.6 1.9 0.6 0.1 0.6 0.0 0.8 2.1 0.0 0.1 0.3 0.0 2.0 1.0 0.9 1.6 0.1 71.6 0.8 0.7 2.3 0.2 0.9 0.5 0.7 0.3 10.3 0.8 0.7 4.8 0.6 1.2 2.6 3.9 3.9 0.2 4.6 0.2 0.7 0.2 0.1 2.6 0.2 0.1 0.1 37.6 0.1 5.1 0.4 0.3 1.9 16.3 30.5 24.9 23.2 16.5 20.2 27.9 27.3 26.7 19.2 28.6 41.7 2.7 25.6 59.3 9.1 11.4 36.3 6.3 54.8 18.8 2.0 22.0 7.4 3.3 14.3 57.2 1.8 0.0 14.5 5.6 22.5 0.0 3.8 8.3 5.3 9.0 16.4 10.3 29.0 0.3 3.3 23.4 32.4 9.2 9.0 76.4 1.9 21.0 13.8 37.1 0.0 0.7 10.7 22.4 75.4 272.8 2.9 15.2 49.0 55.2 1.0 14.1 6.0 3.1 17.1 43.0 3.1 21.0 6.8 5.9 11.8 28.0 5.6 37.7 9.6 6.6 16.1 20.8 3.2 4.1 6.2 32.7 20.4 24.5 0.9 11.9 13.2 BFAR "BAR, RNF47" ENSG00000103429 "Bifunctional apoptosis regulator" Q9NZS9 16 14632931-14669236 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "unprognostic (1.22e-1)" "unprognostic (1.60e-1)" "unprognostic (4.88e-3)" "unprognostic (2.81e-2)" "unprognostic (3.15e-1)" "unprognostic (1.19e-2)" "unprognostic (1.48e-2)" "unprognostic (2.11e-1)" "unprognostic (2.09e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (3.22e-1)" "unprognostic (1.07e-2)" "unprognostic (2.31e-2)" "unprognostic (2.65e-1)" "unprognostic (3.42e-2)" "unprognostic (2.51e-2)" 36.3 24.4 12.2 14.8 13.6 17.2 32.6 14.2 12.5 25.7 14.1 27.2 19.8 25.9 14.5 18.3 23.2 17.3 24.7 11.8 12.6 25.0 22.7 35.5 20.6 13.7 12.9 28.4 46.3 16.2 16.8 25.3 13.7 20.7 15.4 19.4 22.7 13.6 45.6 24.8 25.3 17.5 12.5 22.5 28.3 15.7 13.1 21.3 22.5 26.5 17.5 27.1 23.7 14.2 29.4 37.4 37.3 42.4 35.3 50.6 26.0 44.2 54.9 39.3 41.7 24.3 43.2 47.8 81.9 53.6 33.8 41.1 65.0 41.7 51.4 29.0 25.4 32.2 33.2 78.0 54.7 49.9 36.0 58.4 44.7 37.7 52.4 41.9 61.8 31.2 43.4 36.9 46.0 41.6 34.6 42.1 71.6 26.9 16.0 58.7 48.7 51.1 49.2 33.1 45.9 45.1 36.5 38.7 113.0 37.1 38.4 42.3 49.9 66.3 31.8 35.7 35.7 49.2 54.7 45.4 37.8 44.4 43.7 6.2 7.1 8.4 11.5 9.4 13.4 11.2 9.8 12.0 9.1 8.4 9.4 10.0 4.0 9.8 8.3 6.9 14.7 6.3 12.2 13.6 14.2 12.5 11.8 12.6 13.7 12.9 13.7 12.5 13.1 14.2 49.3 44.8 58.0 10.1 47.2 39.4 39.7 30.8 43.9 34.2 30.0 33.9 20.8 31.5 26.8 23.9 37.5 44.6 55.1 32.0 31.3 49.9 9.4 28.7 36.6 45.8 33.0 37.0 11.2 92.9 81.1 37.3 35.2 54.6 47.5 54.1 46.4 25.3 38.8 25.2 12.9 49.9 28.5 58.6 25.2 7.9 30.1 41.6 19.6 12.2 46.3 29.6 44.3 13.0 13.0 62.1 35.6 26.7 37.2 30.7 47.5 50.6 17.7 37.1 26.3 27.8 31.9 45.4 42.1 30.7 19.7 44.1 47.3 53.8 39.5 36.6 BIN3 ENSG00000147439 "Bridging integrator 3" Q9NQY0 8 22620418-22669148 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Septation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 94.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023769 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "HPA023769: AB_1845361" "unprognostic (4.93e-3)" "unprognostic (4.42e-2)" "unprognostic (6.44e-3)" "unprognostic (1.44e-2)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" "unprognostic (7.36e-2)" "unprognostic (1.68e-1)" "unprognostic (2.65e-2)" "unprognostic (1.67e-2)" "unprognostic (1.81e-1)" "unprognostic (3.79e-1)" "unprognostic (2.53e-2)" "unprognostic (2.20e-3)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (1.66e-1)" 18.6 28.4 13.4 8.5 14.1 40.3 17.6 13.2 16.3 12.4 14.4 11.4 6.8 9.6 9.4 15.8 15.1 9.5 11.5 14.0 13.6 21.0 14.0 11.6 10.4 14.1 13.2 10.4 9.7 12.5 12.6 8.4 13.8 15.5 9.9 7.7 11.6 9.4 9.2 13.9 11.1 8.0 12.8 13.3 12.6 10.4 13.5 13.3 13.2 4.4 10.9 13.5 12.9 13.7 20.6 17.5 7.7 16.6 19.9 18.4 8.6 18.2 31.0 28.4 23.2 7.2 7.9 16.6 8.0 20.0 19.9 22.7 14.9 19.0 19.4 12.6 10.1 13.8 9.0 13.6 16.7 14.3 14.8 19.0 22.2 20.9 11.1 18.0 18.4 9.7 27.5 10.2 14.8 10.0 22.8 31.7 14.6 26.9 7.6 11.4 8.2 8.1 28.4 16.2 4.0 8.8 8.7 6.4 94.2 10.3 6.2 12.7 17.7 8.8 10.8 18.1 13.7 6.8 6.1 15.1 25.1 10.3 58.5 56.3 34.2 78.3 29.0 33.9 30.0 25.8 29.5 21.9 27.5 29.1 28.9 23.5 94.9 36.4 26.1 24.9 41.0 36.9 13.4 14.1 13.2 16.3 14.0 13.6 14.1 13.2 13.8 12.8 13.5 13.7 31.7 9.6 13.0 9.1 16.5 9.8 30.9 32.9 5.2 14.0 11.5 10.0 1.1 18.6 17.2 14.7 41.7 42.8 14.7 24.0 15.6 25.1 28.5 26.7 15.3 21.0 19.8 14.3 13.3 27.6 22.5 14.0 21.4 28.4 31.7 13.6 17.2 6.1 20.2 25.2 9.8 22.1 34.6 9.6 8.7 4.9 18.3 13.0 19.6 8.4 18.6 69.3 32.0 4.0 7.2 41.7 26.1 12.0 8.5 23.4 16.7 13.9 34.1 33.8 13.1 25.4 14.6 18.0 14.0 5.4 11.5 79.4 15.0 24.4 18.2 41.2 BIRC7 "KIAP, ML-IAP, mliap, RNF50" ENSG00000101197 "Baculoviral IAP repeat containing 7" Q96CA5 20 63235883-63240495 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 6.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 12.4;Extravillous trophoblasts: 16.5;Hofbauer cells: 75.8;Melanocytes: 26.6;Muller glia cells: 54.2" "Cancer enriched" "Detected in many" 10 "melanoma: 73.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-MEL-30: 196.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA047850, HPA061283" Enhanced Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "Centrosome, Cytosol" "HPA047850: AB_2680181, HPA061283: " "unprognostic (3.60e-1)" "unprognostic (7.94e-2)" "unprognostic (2.70e-2)" "unprognostic (1.78e-3)" "unprognostic (1.15e-1)" "unprognostic (8.11e-2)" "unprognostic (1.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.62e-3)" "unprognostic (1.24e-2)" "unprognostic (6.90e-2)" "unprognostic (2.27e-1)" "unprognostic (8.82e-3)" "unprognostic (1.22e-2)" "unprognostic (4.77e-2)" "unprognostic (2.55e-2)" "unprognostic (4.84e-2)" 0.8 0.8 0.7 0.3 0.4 0.1 0.4 0.3 1.3 1.7 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.5 0.7 0.9 0.9 0.3 1.1 1.3 0.8 0.7 0.1 0.0 0.0 0.3 6.5 1.1 0.1 0.0 0.6 0.2 0.0 0.0 2.4 0.2 0.0 0.7 0.9 0.1 0.1 1.2 0.0 0.2 0.0 0.2 0.2 0.7 1.5 0.3 4.3 0.1 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 6.6 1.1 0.0 17.8 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 20.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 36.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 196.8 4.4 1.3 0.1 0.0 0.0 1.1 0.0 0.1 0.0 0.1 0.2 0.0 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.3 1.3 0.7 0.9 0.8 0.7 1.1 0.7 1.2 1.5 0.3 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 1.8 0.0 12.4 0.1 0.0 0.0 0.7 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.6 16.5 0.7 0.0 0.0 2.5 0.1 0.0 0.0 75.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.7 26.6 0.0 0.0 54.2 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.5 0.0 0.1 0.0 0.0 BPHL "Bph-rp, MCNAA, VACVase" ENSG00000137274 "Biphenyl hydrolase like" Q86WA6 6 3118374-3153578 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 110.4;liver: 84.8" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 99.7;Proximal tubular cells: 336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036752, HPA036753" Enhanced Approved Mitochondria NA NA 14000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036752: AB_10673662, HPA036753: AB_2675291" "unprognostic (2.93e-1)" "unprognostic (1.29e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-1)" "unprognostic (3.72e-3)" "unprognostic (1.84e-1)" "unprognostic (8.65e-2)" "unprognostic (3.14e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.97e-4)" "unprognostic (4.59e-2)" "unprognostic (9.46e-3)" "prognostic favorable (5.16e-7)" "unprognostic (1.60e-2)" "unprognostic (1.51e-2)" "unprognostic (6.98e-2)" "unprognostic (5.20e-2)" 24.1 15.3 9.4 3.9 9.8 3.5 11.2 9.5 14.5 9.3 11.8 10.6 33.8 7.0 28.8 13.2 11.1 8.9 11.6 10.1 10.8 110.4 84.8 5.2 4.4 9.8 10.2 6.5 11.5 10.8 12.7 5.0 10.7 6.8 9.4 4.2 11.3 4.7 15.5 11.2 32.8 5.8 8.6 3.9 10.0 5.0 9.8 4.8 5.5 12.5 5.9 9.0 9.1 10.8 12.0 13.8 26.8 30.6 22.5 16.2 10.2 7.1 8.7 8.6 11.4 12.4 15.3 18.6 19.7 9.2 21.4 22.1 11.7 8.0 7.6 24.8 10.5 2.7 5.4 21.8 7.9 6.3 1.8 16.9 14.1 6.3 6.0 17.7 15.5 18.8 7.2 3.0 19.9 18.2 14.8 8.3 22.5 21.1 21.9 16.1 17.7 27.9 19.7 30.3 31.7 23.3 13.2 9.0 58.4 39.4 25.6 2.2 7.7 12.5 3.4 13.1 4.9 8.6 27.8 20.4 3.5 4.0 18.4 13.6 9.8 0.0 8.2 12.9 10.9 17.5 9.7 8.4 15.3 12.8 9.1 12.7 0.6 14.6 7.8 8.4 5.4 7.5 9.4 9.8 9.5 14.5 10.1 10.8 9.8 10.2 10.7 8.6 9.8 10.8 15.9 6.4 9.3 11.1 8.2 8.9 8.6 26.0 10.8 11.1 15.1 19.0 4.8 31.5 19.3 16.5 20.9 28.6 5.6 13.6 70.5 28.1 0.5 13.6 14.0 9.1 16.1 6.9 9.3 13.5 32.2 12.2 11.2 8.2 2.5 31.8 6.1 70.9 23.7 16.8 12.8 14.9 38.7 2.2 8.3 1.6 14.9 8.0 32.0 10.3 13.9 12.2 7.2 9.0 4.7 19.6 14.8 13.9 4.5 8.4 99.7 336.3 38.2 6.9 6.6 19.0 12.5 6.8 20.6 13.9 9.2 14.0 7.6 32.9 19.0 8.1 BRMS1 DKFZP564A063 ENSG00000174744 "BRMS1 transcriptional repressor and anoikis regulator" Q9HCU9 11 66337333-66345125 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Repressor "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010824, HPA019637" Approved Approved Centrosome NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Centrosome "CAB010824: , HPA019637: AB_1845448" "unprognostic (1.75e-1)" "unprognostic (2.64e-2)" "unprognostic (2.01e-1)" "unprognostic (4.31e-2)" "unprognostic (1.72e-2)" "unprognostic (5.50e-2)" "prognostic unfavorable (6.74e-4)" "unprognostic (2.99e-1)" "unprognostic (2.62e-1)" "unprognostic (4.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.39e-1)" "unprognostic (1.27e-1)" "unprognostic (5.67e-3)" "unprognostic (2.54e-1)" "unprognostic (6.32e-2)" "unprognostic (1.61e-1)" 27.2 28.1 25.3 24.1 27.0 52.2 27.1 27.2 28.5 22.0 26.9 28.9 26.0 20.5 17.5 36.7 20.0 18.0 26.0 26.6 25.4 35.0 29.1 25.0 32.2 27.4 27.1 19.9 40.9 19.3 17.9 19.5 26.8 33.9 19.2 9.1 30.5 18.3 38.0 41.5 29.6 13.1 26.5 38.3 31.6 31.5 27.1 28.7 26.5 13.8 25.6 25.1 25.8 28.0 80.3 102.4 33.8 56.6 35.1 36.1 47.8 54.4 58.9 95.9 63.9 84.1 51.2 53.5 78.9 53.8 82.5 91.7 64.9 99.2 45.0 63.9 53.9 49.2 54.2 62.1 65.1 71.3 54.9 41.2 104.5 97.0 72.2 29.1 59.9 60.1 59.0 24.3 58.0 128.9 87.5 169.1 73.3 61.2 95.3 73.2 62.2 100.0 60.1 45.6 70.8 57.0 67.2 68.6 180.9 24.6 83.5 43.7 58.2 71.9 68.2 117.1 68.8 50.2 53.8 85.3 93.0 46.2 78.8 45.6 79.4 80.8 61.1 77.3 65.1 79.2 65.2 58.6 62.4 75.6 56.3 54.3 104.2 51.3 69.9 67.3 79.9 67.3 25.3 27.0 27.2 28.5 26.6 25.4 27.4 27.1 26.8 26.5 27.1 28.0 27.2 16.0 26.9 4.2 42.7 58.1 28.5 45.0 33.6 12.3 31.7 27.6 11.7 40.0 22.6 22.0 6.2 61.5 37.1 109.0 54.8 72.6 7.4 25.6 16.6 30.8 32.3 33.7 2.9 117.9 68.5 22.9 33.1 18.6 27.8 21.4 28.2 21.5 67.6 11.8 2.2 54.0 32.6 51.3 41.7 9.9 22.4 39.1 28.4 5.6 68.3 31.7 56.7 3.0 5.1 85.7 85.6 14.7 30.5 40.6 80.5 51.1 22.2 14.9 6.6 23.1 27.3 35.8 39.4 32.2 60.0 71.7 42.5 21.1 61.3 29.8 C10orf90 "bA422P15.2, FATS, FLJ32938" ENSG00000154493 "Chromosome 10 open reading frame 90" Q96M02 10 126424997-126798708 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 112.1" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 819.4" "Cancer enriched" "Detected in some" 5 "melanoma: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SK-MEL-30: 118.8;U-2197: 36.1;U-266/84: 27.2;U-87 MG: 37.0;WM-115: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038648, HPA075229" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA038648: AB_10672721, HPA075229: " "unprognostic (1.21e-2)" "unprognostic (3.34e-1)" "unprognostic (7.50e-2)" "unprognostic (2.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.30e-2)" "unprognostic (1.98e-3)" "unprognostic (5.06e-2)" "unprognostic (9.34e-3)" "unprognostic (3.73e-2)" "unprognostic (9.52e-2)" "unprognostic (1.22e-1)" "unprognostic (5.06e-11)" "unprognostic (2.69e-3)" "unprognostic (9.91e-3)" "unprognostic (1.26e-1)" "unprognostic (2.88e-1)" 0.7 0.0 30.4 0.1 74.4 0.0 4.7 41.9 47.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 29.9 37.4 0.3 0.1 0.0 0.0 60.4 53.8 0.1 0.2 0.0 0.3 0.3 57.0 0.0 0.1 0.0 10.6 0.0 0.1 1.1 0.1 0.0 29.8 0.0 0.0 6.5 68.0 1.1 0.3 0.4 0.7 0.0 0.0 112.1 0.3 0.1 0.0 0.0 0.8 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 2.3 0.0 1.6 0.0 0.9 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 2.6 0.0 0.0 0.0 0.0 118.8 0.0 0.0 0.2 0.0 4.7 0.0 36.1 0.7 0.0 27.2 0.0 37.0 0.0 29.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.4 74.4 41.9 47.7 29.9 37.4 60.4 53.8 57.0 29.8 68.0 112.1 0.2 0.0 0.0 24.5 0.1 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 120.5 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.0 142.7 0.3 0.0 0.0 3.7 0.0 0.0 0.0 181.0 819.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 1.3 0.5 0.0 0.0 4.2 0.1 0.0 0.0 0.0 C11orf24 DM4E3 ENSG00000171067 "Chromosome 11 open reading frame 24" Q96F05 11 68261338-68272001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 107.7;Proximal enterocytes: 162.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 222.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012411, HPA012748" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" Vesicles "HPA012411: , HPA012748: AB_1845526" "unprognostic (1.13e-2)" "unprognostic (2.03e-2)" "unprognostic (1.19e-1)" "unprognostic (8.22e-2)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.31e-2)" "unprognostic (7.91e-2)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.56e-1)" "unprognostic (2.68e-2)" "unprognostic (4.99e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.60e-9)" "unprognostic (2.18e-2)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (8.67e-3)" 25.0 17.6 8.9 20.7 12.2 4.7 21.0 12.1 12.7 23.3 8.2 29.2 53.8 39.2 7.3 15.5 22.2 17.6 31.5 9.7 10.5 17.0 87.4 24.1 15.5 14.4 11.6 19.3 27.3 7.3 14.5 16.1 12.5 22.9 17.4 3.0 34.0 17.6 13.7 15.4 59.4 32.6 11.0 20.8 23.6 14.6 12.8 6.4 17.0 15.2 16.7 22.3 19.4 15.2 44.8 45.5 26.4 51.6 62.1 62.5 29.7 105.4 67.5 51.8 53.1 96.2 26.9 20.1 31.7 131.3 47.2 49.4 39.1 47.4 33.2 22.1 23.1 21.4 44.8 65.3 50.1 18.3 68.7 52.1 34.6 78.8 32.0 31.0 21.2 10.6 37.9 32.2 44.6 55.7 4.5 26.4 44.2 72.1 53.8 8.2 44.8 104.1 23.9 21.1 17.3 31.8 33.3 27.1 222.8 21.8 25.6 15.3 23.3 80.8 50.2 103.3 47.3 39.4 41.4 18.8 65.1 14.1 79.9 16.7 12.1 12.6 14.0 19.0 9.4 26.7 7.9 8.9 19.5 35.7 7.3 7.7 1.8 9.9 14.1 26.7 8.4 12.6 8.9 12.2 12.1 12.7 9.7 10.5 14.4 11.6 12.5 11.0 12.8 15.2 6.8 9.6 3.6 3.3 25.5 14.0 12.2 11.7 9.6 4.8 8.2 8.9 10.4 11.5 6.9 9.2 2.1 11.9 12.4 36.2 1.9 21.9 3.5 5.3 17.8 6.6 4.8 9.1 4.1 31.5 30.7 21.1 18.3 6.8 45.0 5.0 9.3 107.7 15.8 0.0 4.2 50.0 6.1 12.9 23.5 7.1 14.0 12.3 28.4 5.6 14.9 6.8 18.6 6.6 8.5 26.9 16.6 16.1 67.0 13.0 162.5 10.6 9.4 2.9 13.1 11.2 20.2 20.7 27.1 9.6 11.2 10.5 6.5 9.6 15.5 10.6 C15orf40 MGC29937 ENSG00000169609 "Chromosome 15 open reading frame 40" Q8WUR7 15 82988441-83011641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041947, HPA042980" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Golgi apparatus" "HPA041947: , HPA042980: AB_10964298" "unprognostic (8.30e-3)" "unprognostic (2.56e-2)" "unprognostic (3.96e-2)" "unprognostic (1.31e-1)" "unprognostic (3.58e-1)" "unprognostic (2.02e-2)" "unprognostic (1.17e-2)" "unprognostic (3.04e-2)" "unprognostic (8.65e-2)" "unprognostic (2.20e-2)" "unprognostic (8.55e-3)" "unprognostic (7.71e-2)" "prognostic favorable (4.35e-4)" "unprognostic (2.83e-1)" "unprognostic (1.84e-1)" "unprognostic (1.33e-1)" "unprognostic (2.51e-2)" 13.4 13.5 8.3 10.1 8.1 13.9 13.2 12.4 10.8 11.0 6.1 12.4 13.7 9.2 19.8 12.1 9.0 6.5 8.1 8.1 6.7 19.1 13.0 8.2 13.5 8.1 6.3 10.5 12.4 9.7 9.3 7.6 7.6 9.4 8.2 10.2 12.4 5.8 12.4 14.7 12.9 6.1 4.2 11.9 11.2 13.9 7.0 10.7 10.3 6.7 11.2 10.1 10.7 15.3 16.8 19.7 12.8 17.4 15.9 14.4 11.6 10.1 16.0 9.7 10.9 13.7 26.6 16.6 13.4 7.6 23.8 29.5 28.5 20.2 10.9 32.1 19.0 15.7 26.4 15.9 15.3 26.6 15.6 12.1 28.8 16.1 18.1 12.8 16.8 43.6 22.1 26.6 9.3 15.7 22.6 14.3 21.4 23.8 12.5 30.5 17.3 22.7 16.7 23.5 29.7 18.2 26.0 20.4 40.8 16.2 23.3 15.4 10.4 20.0 29.1 15.5 17.7 25.4 42.0 31.8 26.0 26.4 22.4 58.0 20.9 31.2 28.1 22.0 31.4 46.7 29.7 29.5 21.2 38.8 34.7 29.9 20.6 42.2 21.4 29.6 41.1 20.5 8.3 8.1 12.4 10.8 8.1 6.7 8.1 6.3 7.6 4.2 7.0 15.3 27.3 28.9 32.5 16.6 41.1 12.0 27.8 45.2 51.2 28.9 33.6 41.0 11.6 38.6 46.2 25.8 12.5 46.6 22.3 42.3 93.9 47.3 36.7 30.0 21.1 27.2 28.8 32.4 11.6 56.1 30.0 29.9 32.1 19.0 27.8 33.7 26.0 37.7 30.0 30.3 14.3 26.4 34.6 28.4 12.0 30.8 33.2 28.0 26.6 8.4 42.7 32.1 63.8 11.6 19.9 62.7 29.6 36.1 41.2 26.7 77.6 127.3 51.2 30.1 19.7 28.6 25.9 107.3 66.8 46.5 15.3 35.6 39.3 39.9 29.9 26.3 C15orf65 FLJ27352 ENSG00000261652 "Chromosome 15 open reading frame 65" H3BRN8 15 55408495-55418798 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 168.5;Endometrial ciliated cells: 79.4;Respiratory ciliated cells: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.7" "Cell line enhanced" "Detected in many" "hTCEpi: 13.2;SK-MEL-30: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067189 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Cytosol "HPA067189: AB_2685800" "unprognostic (2.77e-2)" "unprognostic (7.42e-2)" "unprognostic (7.50e-2)" "prognostic favorable (3.18e-7)" "unprognostic (1.59e-1)" "unprognostic (9.56e-3)" "unprognostic (1.16e-3)" "unprognostic (6.69e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-1)" "unprognostic (2.25e-1)" "unprognostic (8.89e-2)" "unprognostic (1.84e-3)" "unprognostic (2.09e-1)" "unprognostic (1.81e-1)" "unprognostic (1.42e-1)" "unprognostic (1.80e-1)" 1.3 2.1 2.8 0.5 3.0 0.6 3.2 2.6 3.4 4.3 5.3 4.0 1.8 1.9 6.0 0.8 7.9 3.1 5.6 2.8 3.1 7.2 1.3 2.3 1.1 3.6 3.5 1.2 8.5 4.6 8.9 0.5 3.4 3.3 3.6 7.5 9.0 2.7 6.9 1.4 1.6 2.1 3.1 1.2 6.3 9.0 3.0 1.5 4.0 2.8 1.1 1.6 1.1 2.9 0.9 1.3 2.7 1.7 4.0 5.8 0.4 1.5 2.2 1.2 2.5 0.0 1.5 1.2 4.0 5.1 3.2 1.2 0.0 2.5 0.4 2.5 1.8 1.2 9.3 0.4 7.6 2.8 1.5 1.9 13.2 3.8 1.0 6.9 2.4 0.0 2.3 4.0 5.8 2.1 0.1 7.6 0.7 4.8 3.0 0.5 0.0 10.5 7.0 0.0 7.7 4.3 1.9 3.2 13.0 1.1 6.4 2.7 1.8 2.1 0.9 2.0 0.7 1.8 4.8 1.0 5.9 6.7 1.1 4.7 0.4 1.7 0.2 0.7 0.0 0.9 0.0 0.3 0.3 0.8 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.2 2.8 3.0 2.6 3.4 2.8 3.1 3.6 3.5 3.4 3.1 3.0 2.9 3.3 3.2 1.1 4.6 3.3 1.3 3.7 13.1 2.2 1.7 8.6 10.8 7.8 5.7 8.0 5.5 0.0 1.1 0.5 6.7 17.6 8.8 168.5 79.4 4.1 3.9 3.6 0.4 4.0 11.0 1.5 3.6 5.1 7.2 4.5 1.9 4.6 1.7 2.9 3.3 2.7 18.8 14.2 1.9 1.9 17.0 4.4 1.0 3.6 1.0 0.8 5.1 0.0 1.0 0.9 6.6 16.8 5.7 2.6 4.8 1.9 22.5 47.5 8.2 6.6 3.2 3.4 23.9 3.6 0.8 1.7 0.0 1.0 4.2 4.8 2.1 C1orf216 FLJ38984 ENSG00000142686 "Chromosome 1 open reading frame 216" Q8TAB5 1 35713877-35718894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.8" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028299, HPA031343" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA028299: AB_10601122, HPA031343: AB_2673834" "unprognostic (1.17e-1)" "unprognostic (2.43e-2)" "unprognostic (9.84e-2)" "unprognostic (1.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.15e-4)" "unprognostic (2.23e-1)" "unprognostic (3.81e-1)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.86e-1)" "prognostic unfavorable (7.68e-10)" "unprognostic (3.31e-1)" "unprognostic (3.08e-1)" "unprognostic (2.48e-1)" "unprognostic (5.93e-2)" 10.5 10.6 35.8 6.1 39.1 4.5 7.6 25.1 47.8 10.7 15.8 17.3 3.5 13.2 11.3 5.6 9.1 7.6 11.7 42.6 37.0 4.7 5.3 9.9 7.3 31.6 27.5 8.2 4.4 7.0 9.3 4.7 33.3 8.7 5.3 28.8 5.2 9.9 15.6 7.7 7.9 16.0 27.3 8.8 7.1 9.8 33.4 4.8 6.0 14.7 7.0 10.7 7.9 37.9 7.7 17.6 8.6 12.5 43.5 31.7 6.3 21.1 25.9 31.9 30.3 10.7 16.3 8.3 15.2 32.5 26.0 7.1 24.1 14.6 27.5 31.4 10.3 57.8 27.6 2.9 16.5 28.1 36.6 32.9 18.2 22.8 7.4 23.6 21.2 6.3 23.4 25.6 34.9 12.9 10.5 24.8 13.6 8.4 14.9 7.0 11.5 8.2 11.0 9.0 12.7 12.4 20.3 4.1 44.1 5.3 8.2 12.6 24.8 25.6 19.5 19.0 22.2 7.6 20.3 6.0 25.6 27.6 40.9 0.0 2.7 0.1 4.3 2.8 1.3 2.0 3.3 5.3 2.5 1.5 0.8 3.1 0.0 0.6 2.1 0.5 1.2 2.9 35.8 39.1 25.1 47.8 42.6 37.0 31.6 27.5 33.3 27.3 33.4 37.9 4.9 0.0 2.2 5.9 2.3 6.0 3.5 2.9 0.6 19.6 3.6 2.5 7.1 0.0 1.5 1.8 14.6 2.5 7.1 0.1 0.0 6.0 14.8 1.0 3.7 6.1 1.8 7.8 17.6 2.7 1.5 7.3 1.1 1.6 4.5 5.2 6.4 2.3 7.9 23.5 15.0 0.3 2.0 4.8 6.1 8.5 8.4 5.0 16.0 9.4 6.9 21.0 10.3 7.1 8.7 2.0 0.1 20.7 2.7 1.7 0.1 0.8 0.3 31.8 0.0 6.8 7.8 11.2 5.2 0.2 4.5 1.1 6.2 4.7 0.7 1.5 C2orf76 "AIM29, LOC130355, MGC104437" ENSG00000186132 "Chromosome 2 open reading frame 76" Q3KRA6 2 119302225-119366834 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 78.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044977, HPA055362" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA044977: AB_10961918, HPA055362: AB_2682794" "unprognostic (4.29e-1)" "unprognostic (2.07e-1)" "unprognostic (5.40e-3)" "unprognostic (1.04e-1)" "unprognostic (1.16e-2)" "unprognostic (2.20e-2)" "unprognostic (1.47e-3)" "unprognostic (5.51e-2)" "unprognostic (3.26e-3)" "unprognostic (1.16e-1)" "unprognostic (4.77e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.16e-8)" "unprognostic (3.42e-2)" "unprognostic (2.91e-2)" "unprognostic (7.55e-2)" "unprognostic (9.19e-2)" 20.2 19.7 23.2 10.2 23.3 10.0 22.4 23.8 29.5 13.0 21.3 12.3 6.9 17.1 43.4 16.2 20.5 12.6 16.1 22.2 23.5 19.9 14.1 9.9 15.2 24.3 23.2 17.8 15.7 20.6 10.7 11.3 24.4 16.0 11.7 9.4 16.0 15.4 10.3 20.6 7.6 16.7 24.2 10.9 11.3 19.3 23.0 13.5 20.5 14.5 14.0 13.9 10.9 26.6 17.0 15.7 22.4 14.3 31.7 38.3 12.8 23.4 16.7 15.0 16.3 10.1 11.3 20.7 40.6 24.7 17.4 7.8 10.1 14.9 15.0 17.7 33.5 39.1 11.7 13.5 21.8 15.0 24.6 20.4 25.3 21.3 13.8 19.3 21.7 15.7 12.6 19.6 22.5 25.7 15.7 28.5 12.4 13.3 12.4 9.6 4.7 29.1 33.9 18.0 14.8 16.7 17.0 24.1 33.7 21.0 13.2 52.5 20.3 17.4 13.5 14.6 12.7 12.8 22.5 22.1 17.5 11.1 20.0 29.1 20.9 21.9 19.9 20.2 18.0 20.0 15.2 18.3 21.3 14.7 13.8 19.3 37.2 32.5 12.7 20.1 16.8 11.9 23.2 23.3 23.8 29.5 22.2 23.5 24.3 23.2 24.4 24.2 23.0 26.6 30.3 6.4 11.4 22.5 11.1 25.0 17.2 47.7 17.1 3.3 18.5 19.7 18.5 12.8 24.4 14.7 0.0 26.4 15.2 7.1 78.2 14.7 11.7 27.6 15.4 20.4 10.9 16.4 12.4 17.8 32.4 20.7 9.7 19.7 22.2 8.4 15.0 11.6 26.7 1.7 8.6 11.2 22.4 15.0 23.4 7.7 19.3 13.8 44.4 12.2 20.6 19.8 26.8 14.6 25.2 14.0 9.2 17.0 8.9 11.8 12.2 47.0 42.8 4.6 6.6 13.8 18.8 38.8 22.4 18.8 35.7 20.7 15.3 11.4 10.0 13.0 CA14 ENSG00000118298 "Carbonic anhydrase 14" Q9ULX7 1 150257251-150265078 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 33.3;retina: 39.4;skeletal muscle: 33.7;tongue: 47.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 69.5;Melanocytes: 53.4;Muller glia cells: 164.5;Oligodendrocytes: 25.7" "Cancer enriched" "Detected in many" 5 "melanoma: 23.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "AF22: 102.2;AN3-CA: 65.9;NTERA-2: 83.9;SK-MEL-30: 217.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008482 Approved Approved "Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA008482: AB_1078395" "unprognostic (3.06e-2)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (3.25e-2)" "prognostic favorable (8.47e-4)" "unprognostic (7.28e-2)" "unprognostic (4.48e-2)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (2.47e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" "unprognostic (5.89e-3)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (5.80e-2)" 0.0 0.2 8.6 0.2 14.4 1.2 0.3 15.9 27.6 0.1 33.3 3.8 0.4 0.1 0.4 1.9 1.7 0.6 7.6 8.7 11.3 0.3 8.7 0.2 0.1 14.3 14.0 1.4 0.2 3.4 0.5 0.3 14.6 4.0 0.7 39.4 0.4 20.3 33.7 5.4 1.3 0.5 12.5 0.2 1.2 0.5 13.3 0.0 1.0 47.4 0.0 0.6 0.1 20.6 0.9 0.2 102.2 65.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.7 0.1 0.5 0.0 0.1 0.3 0.2 0.1 0.0 0.2 1.1 0.3 0.3 6.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.1 0.6 0.0 0.9 0.3 0.3 83.9 0.4 1.1 0.1 0.3 0.3 0.0 0.2 3.2 1.8 0.0 0.3 217.9 14.6 0.8 0.4 0.1 0.1 0.2 0.2 0.4 0.9 4.9 0.4 0.7 0.5 0.2 0.0 0.2 0.4 0.4 0.5 0.1 0.5 0.2 0.3 0.0 0.6 0.3 0.3 0.5 0.0 0.1 0.6 0.0 0.0 8.6 14.4 15.9 27.6 8.7 11.3 14.3 14.0 14.6 12.5 13.3 20.6 0.1 3.2 0.5 0.3 0.2 2.2 0.3 0.3 0.0 1.3 0.1 0.0 69.5 0.0 0.7 0.0 0.0 0.4 0.0 0.3 0.0 0.8 0.0 0.3 0.1 0.6 0.0 0.0 0.1 0.7 0.1 3.4 0.0 0.2 0.0 0.0 0.0 6.1 0.1 0.0 0.1 0.3 0.0 0.3 0.9 0.2 0.9 0.1 53.4 0.0 0.0 164.5 0.0 0.0 25.7 1.9 0.3 3.4 0.0 0.3 0.0 0.1 0.1 4.9 0.0 0.6 0.5 0.0 0.2 0.0 0.4 0.3 0.1 0.0 0.2 0.5 CAMLG "CAML, GET2" ENSG00000164615 "Calcium modulating ligand" P49069 5 134738495-134752157 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 845.6;Late spermatids: 1655.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052636, HPA056472" Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "Nucleoplasm, Nucleoli" "HPA052636: AB_2681893, HPA056472: AB_2683143" "unprognostic (9.23e-2)" "unprognostic (8.54e-2)" "unprognostic (2.95e-1)" "unprognostic (2.21e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" "unprognostic (3.68e-2)" "unprognostic (5.41e-3)" "unprognostic (3.07e-1)" "unprognostic (8.54e-2)" "unprognostic (5.34e-3)" "unprognostic (4.58e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (3.26e-2)" "unprognostic (1.43e-2)" "unprognostic (2.19e-1)" "unprognostic (3.16e-1)" 52.3 37.2 50.6 17.5 52.1 31.7 42.1 50.7 69.4 57.0 48.2 54.8 34.4 45.8 48.2 29.5 45.3 27.4 26.9 52.3 55.9 29.7 29.3 28.6 26.2 51.9 53.8 68.6 30.7 27.0 43.1 17.9 54.3 34.9 15.9 29.1 29.0 31.8 60.4 36.7 30.4 28.5 52.8 26.1 36.5 51.3 52.1 25.8 27.0 35.6 25.3 44.2 41.1 53.3 27.5 22.2 33.0 64.1 76.3 118.3 14.4 39.0 55.8 26.8 52.8 38.9 40.1 113.9 56.2 27.5 42.7 34.2 29.2 46.9 35.0 54.3 54.5 29.9 33.2 32.8 56.3 13.7 89.2 96.9 49.5 35.1 57.9 92.3 54.8 49.0 18.6 47.1 39.9 31.2 43.1 58.2 17.1 34.7 21.5 46.2 40.7 44.3 46.0 26.4 52.2 36.9 27.1 15.3 97.1 40.8 48.4 33.9 53.2 24.5 16.4 40.2 35.2 45.8 55.1 42.5 46.2 48.5 14.8 62.0 26.4 60.7 30.5 31.8 41.1 43.5 43.5 38.4 29.1 39.5 45.0 44.2 47.9 31.4 44.6 26.1 52.6 31.6 50.6 52.1 50.7 69.4 52.3 55.9 51.9 53.8 54.3 52.8 52.1 53.3 86.8 38.5 36.4 13.7 92.9 167.1 107.0 113.6 157.1 80.5 121.9 124.7 45.1 100.1 68.9 42.3 25.0 50.3 93.3 42.8 92.0 63.9 845.6 57.6 116.4 99.5 62.4 76.6 29.4 90.9 62.5 107.4 32.6 61.7 123.4 66.6 102.4 69.1 69.9 55.5 32.0 69.4 107.8 111.5 130.8 1655.8 168.0 76.6 96.0 10.3 126.9 127.7 90.6 15.1 18.6 67.5 58.0 132.4 55.2 148.6 158.2 199.1 51.3 71.4 98.6 119.5 109.7 241.5 68.6 119.3 201.6 73.2 101.6 67.9 90.9 107.9 CANX "CNX, IP90, P90" ENSG00000127022 Calnexin P27824 5 179678628-179731641 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 817.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 528.3;SK-MEL-30: 790.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004738, HPA009433, HPA009696" Enhanced Enhanced "Endoplasmic reticulum" NA NA 13000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "CAB004738: AB_626784, HPA009433: AB_1078380, HPA009696: AB_1078379" "unprognostic (6.56e-2)" "unprognostic (9.34e-3)" "prognostic favorable (1.38e-4)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" "unprognostic (1.41e-2)" "unprognostic (4.66e-3)" "unprognostic (8.57e-2)" "unprognostic (4.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.17e-3)" "unprognostic (4.48e-2)" "unprognostic (2.28e-1)" "unprognostic (1.87e-1)" "unprognostic (7.12e-2)" "prognostic unfavorable (3.17e-4)" "unprognostic (2.15e-1)" 128.3 112.8 15.0 36.3 17.6 76.0 110.6 18.8 31.1 121.4 25.1 108.7 45.0 137.7 171.7 106.7 109.8 6.2 137.5 13.8 24.1 121.4 193.2 112.7 18.4 24.7 24.1 129.6 209.7 9.6 96.5 75.0 20.2 96.0 62.6 68.0 123.3 17.8 111.6 83.5 97.4 85.0 19.2 73.2 115.2 75.0 17.9 9.0 159.2 53.6 16.6 112.0 95.6 22.6 13.0 91.5 89.5 53.0 295.4 229.3 37.9 261.4 342.8 341.2 298.2 148.2 49.6 309.3 351.0 127.8 121.4 18.7 120.2 121.1 405.9 64.6 6.3 63.0 247.8 22.9 399.9 82.9 50.0 39.1 313.5 118.6 528.3 56.1 93.9 23.9 43.2 99.9 39.9 51.2 40.9 15.1 9.4 11.7 6.4 43.2 71.3 24.9 252.1 82.8 24.4 8.0 62.7 16.7 790.3 182.7 267.3 16.3 234.7 49.9 56.5 36.1 200.2 19.7 87.2 46.1 53.3 50.4 46.5 51.8 61.8 17.4 29.9 38.9 34.4 14.4 21.2 25.0 47.6 10.0 15.3 15.6 9.6 32.1 30.1 38.7 16.4 74.1 15.0 17.6 18.8 31.1 13.8 24.1 24.7 24.1 20.2 19.2 17.9 22.6 187.0 198.7 296.6 53.5 109.4 148.5 115.4 181.3 152.0 117.4 245.8 153.5 537.0 185.8 247.0 182.1 158.4 162.5 148.6 174.3 49.0 173.6 225.5 160.9 253.9 204.0 178.0 133.3 45.5 153.5 245.8 202.8 156.5 255.5 197.9 137.7 157.5 438.7 227.7 159.9 77.0 250.0 134.3 206.4 215.6 817.5 159.1 218.3 176.1 44.0 181.1 213.8 84.5 63.3 79.4 153.1 125.1 191.1 327.3 249.5 188.2 196.4 294.3 160.9 92.1 114.6 211.2 158.4 72.7 182.3 161.8 244.8 105.8 183.1 251.0 157.8 CAPN3 "CANP3, LGMD2, LGMD2A, nCL-1, p94" ENSG00000092529 "Calpain 3" P20807 15 42359498-42412949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 279.2;skeletal muscle: 905.9;tongue: 377.4" "Group enriched" "Detected in many" 5 "Early spermatids: 512.5;Late spermatids: 183.6;Melanocytes: 482.0;Oligodendrocytes: 220.2" "Cancer enriched" "Detected in some" 10 "melanoma: 9.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 27 "SK-MEL-30: 238.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040052 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA040052: AB_2676821" "unprognostic (1.06e-2)" "unprognostic (1.31e-1)" "unprognostic (4.00e-2)" "unprognostic (8.71e-2)" "unprognostic (1.53e-1)" "unprognostic (1.72e-2)" "unprognostic (2.11e-4)" "unprognostic (3.12e-3)" "unprognostic (2.82e-1)" "unprognostic (2.47e-1)" "unprognostic (2.37e-3)" "unprognostic (3.26e-2)" "unprognostic (3.91e-4)" "unprognostic (5.56e-3)" "unprognostic (2.43e-1)" "unprognostic (8.93e-3)" "unprognostic (1.38e-1)" 13.5 8.8 136.1 4.0 206.6 47.6 14.1 194.2 243.3 18.8 113.0 13.3 3.1 11.2 163.7 14.5 13.7 4.5 16.1 142.9 159.9 93.6 36.9 21.5 7.0 212.0 194.9 15.7 8.7 2.4 11.3 3.0 212.1 16.0 5.3 7.5 18.6 5.2 905.9 54.9 14.0 4.7 155.2 19.1 8.9 30.8 187.8 3.4 10.7 377.4 5.1 11.7 15.5 279.2 0.5 0.3 0.6 1.1 8.8 6.1 0.6 2.6 1.9 0.5 0.8 1.2 0.5 0.2 0.9 1.6 0.4 3.7 0.4 3.5 0.3 0.9 0.8 0.8 0.8 4.1 0.6 1.0 1.5 4.7 3.7 0.8 0.7 1.5 0.1 0.7 0.2 1.8 0.7 0.1 0.2 1.2 0.4 0.2 0.9 1.1 0.4 1.9 1.9 1.3 0.4 0.1 0.2 0.5 238.0 1.0 0.0 5.4 0.9 0.3 0.4 2.6 0.7 1.5 2.1 0.2 0.4 2.4 1.8 0.5 1.0 0.1 0.7 0.2 0.8 0.3 0.1 0.3 0.5 0.5 0.1 0.9 0.9 0.6 0.1 0.5 0.4 0.6 136.1 206.6 194.2 243.3 142.9 159.9 212.0 194.9 212.1 155.2 187.8 279.2 0.5 12.8 34.5 16.0 2.9 20.1 0.8 2.2 3.4 2.2 0.4 0.3 0.4 1.5 4.4 1.8 2.1 0.7 1.4 2.0 1.9 0.1 512.5 0.5 0.6 2.2 0.0 0.0 4.0 0.0 0.6 1.6 3.6 0.7 1.3 0.4 2.2 8.7 32.7 0.0 5.2 1.8 2.0 4.4 11.6 183.6 5.3 2.9 482.0 13.1 2.5 3.7 2.1 4.5 220.2 0.0 5.4 3.4 0.6 0.9 2.4 59.5 2.6 3.9 0.0 13.8 1.6 15.9 4.7 1.6 8.5 3.3 1.8 1.2 2.3 0.8 CBX4 "hPC2, NBP16, PC2" ENSG00000141582 "Chromobox 4" O00257 17 79833156-79839440 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 130.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-BR-3: 110.8;SK-MEL-30: 130.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008228, HPA012021" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies" "HPA008228: AB_1078413, HPA012021: AB_2668603" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "unprognostic (1.72e-2)" "unprognostic (1.86e-1)" "unprognostic (3.97e-2)" "unprognostic (8.80e-2)" "unprognostic (5.39e-3)" "unprognostic (1.49e-1)" "unprognostic (2.55e-1)" "unprognostic (1.40e-2)" "unprognostic (7.62e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (8.72e-8)" "unprognostic (7.49e-2)" "unprognostic (2.87e-1)" "unprognostic (3.99e-2)" "unprognostic (1.07e-1)" 9.3 14.2 9.6 11.1 10.8 130.3 9.0 8.8 12.5 9.1 0.0 7.9 7.1 6.3 4.6 20.7 8.1 6.3 16.0 12.4 9.7 10.6 21.6 12.3 14.6 11.5 9.5 9.6 19.0 17.0 19.1 15.2 10.7 9.3 3.2 12.3 13.2 4.6 3.4 31.6 11.9 3.8 8.2 20.9 12.9 6.9 12.2 23.1 8.6 1.4 7.2 6.7 10.3 16.6 32.1 28.3 8.4 36.3 5.2 4.7 23.5 14.3 8.5 5.1 5.4 20.5 17.5 12.3 19.7 5.6 11.4 16.3 9.3 9.5 3.8 13.3 17.7 7.0 28.0 38.4 25.4 37.0 52.5 6.5 54.4 4.7 8.4 8.5 4.3 35.5 21.7 67.5 5.5 23.0 50.9 37.7 4.6 33.2 28.2 51.9 8.6 56.3 7.2 15.3 8.7 16.6 21.4 110.8 130.9 3.5 26.3 58.3 11.2 29.8 26.3 18.4 18.6 58.0 32.4 35.0 18.7 31.6 40.4 1.6 0.5 1.8 0.9 0.6 0.6 1.5 1.2 1.3 0.3 1.5 1.4 1.3 2.1 0.4 0.7 1.7 0.2 0.6 9.6 10.8 8.8 12.5 12.4 9.7 11.5 9.5 10.7 8.2 12.2 16.6 40.4 3.2 15.7 4.6 31.8 23.3 5.4 13.4 36.5 31.7 65.2 79.8 51.6 30.0 12.1 1.8 22.9 34.2 77.6 26.6 0.0 7.5 0.2 63.9 19.3 21.6 52.7 7.8 5.5 7.3 5.0 15.8 20.9 62.8 7.0 22.3 15.7 16.3 13.8 20.2 5.5 49.5 2.0 19.8 17.0 1.0 4.4 35.4 17.8 12.2 15.4 39.2 15.5 6.0 11.6 10.0 18.4 5.7 26.1 6.3 9.6 2.8 14.6 44.3 6.6 15.3 24.4 0.5 2.4 65.7 30.7 8.6 42.5 13.7 29.7 5.2 CCDC71L "C7orf74, FLJ36031" ENSG00000253276 "Coiled-coil domain containing 71 like" Q8N9Z2 7 106654360-106661158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067925 Approved Approved "Golgi apparatus,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Actin filaments" Cytosol "HPA067925: AB_2685925" "unprognostic (1.51e-1)" "prognostic unfavorable (9.08e-4)" "unprognostic (7.26e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-2)" "unprognostic (1.95e-3)" "unprognostic (9.94e-2)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (2.38e-3)" "unprognostic (6.03e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.53e-6)" "unprognostic (3.34e-2)" "unprognostic (3.72e-1)" "unprognostic (2.26e-1)" "unprognostic (6.35e-2)" 51.5 9.8 2.7 19.6 2.7 15.8 18.7 2.0 2.9 13.1 3.3 14.6 6.5 16.9 2.8 6.8 36.2 10.8 8.2 2.9 3.2 18.1 46.7 22.1 9.6 8.2 2.8 10.1 9.3 5.2 6.4 3.7 3.7 11.2 5.4 1.0 12.6 6.6 5.3 6.2 15.8 7.2 3.3 18.7 16.3 6.9 4.6 14.5 10.2 2.5 8.0 40.0 9.3 3.6 24.8 5.1 7.4 8.9 16.3 15.4 0.0 37.0 47.5 14.2 15.4 0.7 15.3 16.5 12.6 63.3 27.1 2.8 3.6 10.7 11.7 38.7 8.5 2.1 0.9 0.0 25.5 8.4 19.4 13.2 6.4 6.5 3.7 24.1 50.0 9.2 56.0 39.9 17.1 7.1 11.5 13.3 16.0 2.0 17.0 15.4 2.1 3.3 7.3 1.4 3.2 22.1 23.9 8.6 55.9 15.4 3.9 10.1 22.0 31.4 2.9 3.7 14.6 38.4 3.8 13.5 24.3 10.8 35.3 4.9 0.6 1.8 1.1 0.4 0.8 1.3 0.8 0.8 0.4 0.9 0.4 0.6 4.1 0.6 0.7 1.4 1.7 0.5 2.7 2.7 2.0 2.9 2.9 3.2 8.2 2.8 3.7 3.3 4.6 3.6 44.0 3.2 11.6 1.0 9.4 8.2 50.5 2.1 6.8 4.3 39.9 33.0 6.2 18.6 1.6 5.5 2.1 3.0 26.2 12.9 11.7 7.4 1.2 18.7 78.7 21.4 6.6 11.6 1.8 10.7 7.4 47.8 3.6 20.2 12.0 3.3 45.7 34.4 8.1 6.7 2.8 7.3 4.1 10.0 13.9 2.1 21.8 22.5 12.4 1.9 6.5 5.0 10.3 2.5 1.8 13.9 10.1 17.7 4.3 11.0 10.1 4.7 6.8 4.8 0.0 24.5 30.1 7.1 4.9 4.0 5.1 3.3 13.7 3.4 9.5 18.3 CCDC91 "DKFZp779L1558, FLJ11088, p56" ENSG00000123106 "Coiled-coil domain containing 91" Q7Z6B0 12 28133249-28581511 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 18 "Early spermatids: 2093.1;Late spermatids: 7910.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038169 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" Nucleoplasm "HPA038169: AB_10672506" "unprognostic (6.25e-2)" "unprognostic (4.25e-2)" "unprognostic (3.67e-2)" "unprognostic (1.91e-2)" "unprognostic (6.71e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.98e-2)" "unprognostic (2.44e-2)" "unprognostic (4.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.74e-1)" "prognostic unfavorable (7.69e-4)" "unprognostic (1.05e-1)" "unprognostic (2.44e-2)" "unprognostic (5.85e-2)" "unprognostic (2.38e-1)" 17.5 18.3 15.0 13.0 15.8 12.3 16.1 23.2 29.3 11.5 3.5 14.4 12.1 17.8 17.3 14.3 12.3 14.6 30.9 16.6 12.3 20.2 14.3 12.0 16.4 20.7 13.8 17.7 27.1 30.8 12.1 8.5 20.7 15.1 12.6 27.1 13.6 14.0 41.6 10.2 13.1 13.0 11.1 13.6 17.1 34.5 14.6 21.7 24.6 21.7 13.7 16.6 10.5 20.7 21.2 14.8 13.4 0.4 13.6 12.6 25.1 17.5 18.5 15.1 19.3 8.4 27.6 11.0 14.7 20.9 9.0 23.7 12.3 28.2 22.6 29.7 10.2 36.2 29.4 7.7 21.3 35.0 17.1 12.5 27.6 15.0 43.7 28.5 12.3 19.2 33.4 36.0 14.6 7.6 34.8 29.7 27.5 16.2 13.5 21.1 38.7 18.3 24.6 14.3 11.3 20.4 32.7 10.9 55.4 36.4 21.3 27.3 9.3 31.8 22.1 31.5 10.3 44.4 52.5 30.1 27.6 28.0 18.4 21.8 2.3 3.6 5.1 4.5 6.7 6.7 6.5 7.4 3.4 5.2 7.6 7.0 0.7 7.1 5.9 4.1 8.4 3.4 15.0 15.8 23.2 29.3 16.6 12.3 20.7 13.8 20.7 11.1 14.6 20.7 23.4 38.5 41.0 129.3 47.2 34.9 37.4 49.5 34.7 61.5 42.1 36.8 80.8 20.0 40.8 22.0 45.9 14.0 48.4 26.0 43.0 46.2 2093.1 36.9 19.0 19.7 38.4 19.1 199.3 47.3 16.3 24.8 21.4 26.2 40.4 21.9 11.7 26.7 30.6 45.4 266.0 23.9 28.5 35.0 39.3 7910.6 57.8 39.0 37.4 135.9 35.7 52.0 53.5 152.8 221.0 33.8 25.0 51.9 34.2 33.6 25.5 35.0 54.5 74.9 39.5 28.6 31.7 72.0 39.0 19.9 40.5 16.0 50.6 28.5 18.3 33.6 CD58 LFA3 ENSG00000116815 "CD58 molecule" P19256 1 116514534-116571039 "CD markers, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 144.1;Langerhans cells: 195.9;monocytes: 156.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 135.9" "Low region specificity" "Detected in all" NA NA 6500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (4.48e-3)" "unprognostic (3.20e-1)" "unprognostic (2.95e-2)" "unprognostic (4.03e-2)" "unprognostic (8.45e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (2.32e-6)" "unprognostic (9.84e-2)" "unprognostic (7.17e-2)" "unprognostic (4.72e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (2.82e-1)" "unprognostic (1.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.68e-2)" "unprognostic (2.17e-2)" "unprognostic (9.66e-2)" 22.7 10.1 7.5 24.8 8.2 57.9 18.0 8.0 10.5 13.6 10.2 22.3 28.8 12.8 16.1 25.4 12.5 21.5 34.3 7.4 8.8 20.0 12.7 29.1 19.0 9.2 8.4 5.4 7.0 11.9 6.7 16.9 9.4 9.3 29.0 2.0 20.7 10.3 8.7 20.0 29.6 16.9 8.6 24.7 19.0 6.8 9.0 9.7 13.2 10.8 20.3 29.7 19.7 10.2 36.4 20.5 14.7 14.2 24.4 40.7 9.3 18.2 31.3 31.0 30.2 9.2 68.4 6.5 33.2 31.8 36.2 45.9 11.0 31.4 32.7 35.8 12.8 32.8 36.9 12.9 15.5 45.8 43.5 11.2 41.4 25.9 23.0 66.4 17.9 8.5 29.4 135.9 19.2 64.7 19.8 34.6 7.3 53.7 22.3 38.4 49.9 8.6 63.0 29.4 4.9 10.3 36.6 26.9 108.3 15.1 14.0 16.8 33.8 22.3 17.1 30.3 47.2 20.6 39.4 4.6 51.3 22.4 113.2 133.7 50.6 89.8 37.3 51.0 26.1 20.7 32.7 31.7 43.9 9.5 4.2 18.2 165.7 18.5 64.4 5.0 64.3 37.4 7.5 8.2 8.0 10.5 7.4 8.8 9.2 8.4 9.4 8.6 9.0 10.2 52.3 9.6 31.5 10.1 23.8 18.2 20.0 144.1 15.4 0.2 9.9 7.1 28.9 30.0 63.2 14.7 0.0 4.4 40.2 48.1 3.9 39.4 3.2 16.0 5.1 38.1 10.8 46.7 3.2 27.6 1.6 31.9 13.3 19.0 53.0 3.4 28.2 7.7 58.7 1.7 1.5 18.7 34.6 33.0 195.9 3.6 10.5 72.2 12.4 45.0 156.1 3.3 34.0 4.5 1.4 46.7 41.7 11.7 24.3 16.9 46.3 26.5 41.3 0.7 32.9 27.9 23.6 11.3 2.4 28.2 27.8 1.9 44.7 9.6 18.6 42.6 CD63 "ME491, MLA1, TSPAN30" ENSG00000135404 "CD63 molecule" P08962 12 55725323-55729707 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1857.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 4897.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010088, CAB026356, HPA073506" Supported Supported Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB026356: AB_629864, HPA010088: AB_1846323, HPA073506: " "unprognostic (8.76e-3)" "unprognostic (8.81e-2)" "unprognostic (1.27e-1)" "unprognostic (1.28e-3)" "unprognostic (9.48e-2)" "unprognostic (3.66e-3)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.11e-1)" "unprognostic (6.50e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-2)" "unprognostic (3.10e-1)" "unprognostic (2.70e-2)" "unprognostic (4.82e-2)" "unprognostic (5.21e-2)" "unprognostic (1.85e-3)" "unprognostic (9.02e-2)" 954.0 882.1 509.4 457.9 526.5 747.2 769.6 532.6 717.1 715.6 611.8 809.3 394.5 854.6 1492.1 396.1 647.3 607.0 1152.2 508.5 565.7 625.3 565.1 882.2 325.0 564.7 539.9 645.9 830.1 524.7 486.6 588.0 544.3 520.0 736.0 269.1 871.6 547.4 919.3 410.0 559.3 744.5 534.9 597.7 790.8 224.3 583.6 193.3 657.7 587.4 284.9 835.3 539.7 561.7 481.0 669.0 432.6 430.8 4897.7 2932.4 577.5 1914.8 3104.6 979.2 1048.9 750.3 939.2 120.5 581.2 2608.7 787.7 436.3 301.7 732.6 1197.9 372.5 248.7 760.9 542.8 443.3 2006.7 338.5 1699.0 2315.1 639.7 1164.8 979.2 2305.1 1052.2 64.6 386.8 936.3 3062.5 626.3 64.1 439.5 395.7 1062.7 880.7 146.0 949.3 345.7 1699.3 1433.6 170.1 425.8 528.3 392.5 3348.6 630.4 546.4 1089.6 948.0 710.1 514.8 984.9 649.8 377.3 239.3 92.5 2023.9 208.1 1326.3 1279.9 610.3 1857.5 323.2 458.8 235.2 111.0 126.9 260.0 473.0 73.9 55.9 186.0 656.0 733.0 320.4 309.8 121.6 850.4 509.4 526.5 532.6 717.1 508.5 565.7 564.7 539.9 544.3 534.9 583.6 561.7 798.7 512.8 689.0 28.1 147.6 567.2 1382.5 3135.4 155.4 190.3 606.5 601.1 820.9 836.4 1789.7 875.4 152.2 608.3 322.0 1083.4 232.8 2621.2 16.7 446.7 766.7 916.3 581.1 97.0 8.8 3429.0 2756.5 1538.0 371.1 727.3 1030.0 531.6 739.6 423.9 3372.5 33.7 9.3 1251.6 1715.1 854.6 1698.3 65.5 1727.3 1146.7 1993.9 11.2 575.7 893.8 487.1 21.1 26.5 3437.4 1394.0 1157.0 326.9 2039.2 878.1 794.2 1012.6 258.8 1255.6 1845.2 1278.7 43.8 68.9 137.1 400.5 2708.1 310.4 645.8 761.6 1868.9 CDK2 ENSG00000123374 "Cyclin dependent kinase 2" P24941 12 55966781-55972789 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 92.8;Extravillous trophoblasts: 84.7;Melanocytes: 87.2;Syncytiotrophoblasts: 170.7" "Cancer enhanced" "Detected in all" "melanoma: 88.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 540.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013115, HPA066915" Enhanced Enhanced Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Centrosome, Cytosol" "CAB013115: AB_2536375, HPA066915: AB_2685748" "unprognostic (2.36e-2)" "unprognostic (2.60e-1)" "unprognostic (3.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.94e-4)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (4.67e-2)" "unprognostic (5.38e-3)" "unprognostic (4.69e-3)" "prognostic unfavorable (1.46e-10)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (6.75e-2)" 15.3 9.2 3.5 16.3 3.4 36.0 14.2 3.6 4.9 13.4 6.4 12.5 9.8 13.7 6.3 14.9 13.7 10.8 10.9 3.5 3.8 14.7 16.2 22.9 21.6 4.7 4.0 16.3 10.0 7.9 4.9 47.3 4.1 12.6 14.9 6.5 10.9 14.3 7.0 22.7 12.3 19.5 4.2 14.5 12.2 6.6 4.1 37.2 9.6 8.1 24.8 18.1 12.9 3.9 81.7 39.1 93.6 52.4 19.2 24.9 172.2 98.9 53.5 123.3 114.8 89.4 76.3 77.5 70.9 37.9 46.4 50.8 73.4 44.9 126.8 86.9 68.0 89.0 65.0 34.6 6.3 70.4 61.4 12.6 10.9 83.8 29.1 36.1 63.1 76.8 85.6 68.0 88.3 60.8 149.9 61.7 36.9 55.8 60.7 143.7 86.2 57.1 36.5 77.1 37.4 48.1 114.1 41.7 540.3 54.9 88.9 51.1 34.5 82.9 76.3 65.0 71.0 37.4 46.3 95.5 47.4 51.1 74.2 3.6 2.6 2.2 4.7 2.7 4.6 6.5 2.1 3.5 1.9 3.7 2.0 3.7 1.2 3.4 1.2 7.9 5.4 3.3 3.5 3.4 3.6 4.9 3.5 3.8 4.7 4.0 4.1 4.2 4.1 3.9 17.9 16.0 4.8 1.3 7.3 28.0 23.9 6.2 12.5 0.0 14.5 8.9 3.1 11.5 7.6 1.8 0.0 92.8 7.1 3.7 1.9 11.5 0.6 7.4 6.5 18.2 5.4 14.7 0.1 5.7 84.7 15.7 9.2 13.0 10.8 12.0 10.4 9.1 13.3 1.7 0.1 7.2 6.1 4.7 43.8 0.8 14.9 4.9 87.2 1.9 28.4 4.2 5.2 0.0 0.5 12.3 1.5 4.5 11.8 13.4 2.8 4.5 4.4 3.6 0.0 10.1 11.6 3.1 7.4 14.5 31.4 170.7 9.6 4.8 9.7 19.3 CDK2AP2 "DOC-1R, p14" ENSG00000167797 "Cyclin dependent kinase 2 associated protein 2" O75956 11 67506497-67508649 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038872, HPA047599" Uncertain Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA038872: , HPA047599: AB_10963069" "unprognostic (2.44e-1)" "unprognostic (5.01e-2)" "unprognostic (1.42e-1)" "prognostic favorable (8.80e-4)" "unprognostic (6.24e-2)" "unprognostic (2.30e-2)" "unprognostic (8.85e-3)" "unprognostic (1.42e-1)" "unprognostic (5.65e-2)" "unprognostic (3.85e-3)" "unprognostic (4.91e-3)" "unprognostic (2.06e-1)" "prognostic unfavorable (5.20e-4)" "unprognostic (7.58e-2)" "unprognostic (3.11e-1)" "unprognostic (6.96e-2)" "unprognostic (1.73e-3)" 45.6 69.3 83.5 46.1 87.6 32.1 34.2 90.5 107.0 40.7 76.3 46.6 42.9 41.2 85.8 45.2 37.5 27.2 98.5 82.8 87.3 103.0 109.7 46.1 64.8 99.2 89.3 27.9 67.9 25.1 43.7 29.8 95.5 41.9 28.1 25.7 47.2 45.7 23.3 19.7 40.5 30.3 91.5 47.1 47.8 12.6 87.1 55.7 78.0 22.6 48.2 42.8 27.2 93.1 92.9 77.6 33.3 72.4 55.0 19.8 46.9 30.0 25.7 54.8 43.6 104.2 121.6 58.1 111.0 32.6 64.4 67.7 59.5 77.4 16.7 156.0 29.7 36.2 60.8 81.8 113.2 32.7 48.8 17.5 84.8 47.3 93.5 44.2 64.3 86.9 32.5 204.4 23.7 183.5 196.6 111.3 35.2 221.7 83.4 83.6 18.4 245.3 129.1 30.4 23.2 50.9 44.2 130.5 150.8 30.3 73.0 70.0 35.6 26.5 46.4 61.7 27.7 55.0 39.8 65.7 73.2 49.3 34.6 284.3 119.2 266.2 297.9 222.7 261.5 229.6 221.4 267.7 174.8 222.3 117.4 176.3 97.5 292.7 266.1 793.7 291.1 215.2 83.5 87.6 90.5 107.0 82.8 87.3 99.2 89.3 95.5 91.5 87.1 93.1 54.6 64.1 86.2 4.2 112.0 67.0 47.0 118.3 186.1 27.8 88.8 75.3 76.6 88.6 80.3 117.7 31.3 94.9 206.5 187.0 215.2 85.1 1.7 98.2 50.4 56.8 102.8 42.5 3.5 53.2 192.7 49.0 78.5 104.1 74.8 49.5 45.7 131.3 84.6 33.7 3.6 151.1 81.4 46.8 94.9 2.6 24.5 71.5 113.8 11.2 109.8 61.1 171.0 6.0 14.0 99.1 158.5 30.5 240.8 71.1 139.6 329.7 64.6 29.4 26.3 22.0 76.2 10.2 31.1 170.3 51.0 194.4 131.4 30.1 123.2 76.4 CDK5R1 "Nck5a, p35, p35nck5a" ENSG00000176749 "Cyclin dependent kinase 5 regulatory subunit 1" Q15078 17 32486993-32491253 "Predicted intracellular proteins" "Biological rhythms" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 63.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 45.9;Early spermatids: 21.2;Excitatory neurons: 36.6;Inhibitory neurons: 31.6;Late spermatids: 18.9" "Cancer enhanced" "Detected in many" "melanoma: 14.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "SCLC-21H: 58.1;SH-SY5Y: 15.6;SK-MEL-30: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000252 Approved Nucleoplasm,Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "HPA000252: AB_2665953" "unprognostic (1.08e-1)" "unprognostic (9.13e-2)" "unprognostic (1.79e-2)" "unprognostic (3.65e-1)" "unprognostic (1.97e-1)" "unprognostic (8.09e-2)" "unprognostic (2.74e-5)" "unprognostic (1.81e-2)" "unprognostic (3.32e-1)" "unprognostic (2.18e-1)" "unprognostic (5.90e-2)" "unprognostic (5.60e-1)" "unprognostic (6.98e-2)" "unprognostic (1.60e-1)" "unprognostic (7.92e-2)" "unprognostic (8.81e-2)" "unprognostic (1.03e-1)" 0.8 2.8 37.8 7.1 50.8 5.4 1.2 11.0 63.5 1.5 0.0 0.9 1.4 0.9 0.2 7.5 0.7 0.9 1.1 53.4 21.1 0.8 1.0 0.8 13.9 3.2 10.5 2.6 1.4 0.7 6.9 0.6 4.5 0.6 0.8 10.4 1.1 0.5 2.3 1.9 3.6 0.6 3.5 12.1 1.6 7.2 21.7 4.2 0.5 0.8 14.1 0.8 3.1 34.2 3.9 2.2 9.8 3.1 1.1 1.8 1.1 2.4 1.4 2.9 3.7 5.7 0.9 1.9 2.2 2.0 2.4 1.8 3.8 2.4 3.8 0.7 7.3 0.7 1.1 2.3 0.5 1.3 1.9 1.1 5.8 2.9 2.4 1.1 2.1 6.9 3.9 2.2 6.2 1.6 3.4 1.5 6.2 1.4 2.1 2.9 5.9 7.1 1.4 1.7 58.1 15.6 2.3 1.3 43.8 1.4 2.5 4.4 2.2 4.0 5.9 1.6 6.3 1.1 1.5 1.9 3.4 5.6 9.7 0.0 0.3 0.4 0.8 0.3 0.6 0.2 1.1 0.4 0.0 0.1 1.5 0.9 1.2 0.2 0.1 0.6 0.1 0.6 37.8 50.8 11.0 63.5 53.4 21.1 3.2 10.5 4.5 3.5 21.7 34.2 1.7 0.0 1.5 6.5 13.1 1.5 0.5 1.0 7.4 15.9 3.7 2.3 3.6 0.0 0.8 0.0 45.9 0.6 10.1 0.3 0.0 0.2 21.2 1.1 1.3 1.2 0.0 0.0 36.6 0.6 0.3 1.2 0.5 1.5 0.0 1.6 0.7 0.7 0.9 1.7 31.6 1.4 2.0 3.5 0.5 18.9 0.0 1.3 3.6 2.8 2.0 18.4 10.3 9.5 11.9 1.2 1.2 0.7 0.9 1.2 0.4 1.5 1.0 6.3 0.0 2.9 3.1 6.7 4.3 8.8 1.3 1.1 7.1 1.9 1.1 0.5 CEBPB "C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5" ENSG00000172216 "CCAAT enhancer binding protein beta" P17676 20 50190830-50192668 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 765.6;Suprabasal keratinocytes: 800.1;Syncytiotrophoblasts: 1409.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.7" "Group enriched" "Detected in many" 8 "granulocytes: 16.7;monocytes: 7.7" "Cell line enhanced" "Detected in all" "SK-MEL-30: 169.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB004213, HPA061355, HPA062267" Supported Enhanced Nucleoplasm Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB004213: AB_626772, HPA061355: AB_2684487, HPA062267: AB_2684731" "unprognostic (2.30e-2)" "unprognostic (2.64e-1)" "unprognostic (1.24e-2)" "unprognostic (1.09e-2)" "unprognostic (9.48e-2)" "unprognostic (2.24e-2)" "unprognostic (1.32e-1)" "unprognostic (1.40e-3)" "unprognostic (1.79e-2)" "unprognostic (9.85e-3)" "unprognostic (9.26e-3)" "unprognostic (6.55e-2)" "prognostic unfavorable (2.44e-12)" "unprognostic (7.29e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-2)" "unprognostic (7.63e-2)" 160.7 125.5 26.6 63.9 29.4 43.2 86.5 24.4 29.8 95.5 36.7 60.0 13.1 72.4 5.8 43.2 94.9 27.6 59.3 29.7 32.4 39.3 228.7 139.5 11.2 34.8 36.4 89.6 35.6 10.8 28.4 37.8 29.2 60.3 7.1 4.6 49.1 12.3 202.2 99.1 43.4 15.5 35.7 93.1 57.7 9.0 33.3 6.3 57.5 44.3 7.3 64.9 67.2 31.5 26.4 11.8 1.3 13.9 63.7 24.9 112.7 34.9 54.6 23.5 20.7 12.0 23.9 17.1 64.5 14.5 115.4 35.3 3.7 34.2 15.9 12.5 8.3 5.2 15.0 17.8 78.3 8.7 32.9 26.7 88.5 29.9 52.9 49.0 3.3 17.4 25.4 31.0 15.0 9.9 4.1 19.0 7.3 24.8 33.6 12.3 3.4 20.1 7.9 6.3 6.7 4.4 28.9 70.7 169.6 7.4 18.8 48.1 4.5 48.6 37.2 42.1 34.0 64.6 29.5 15.9 88.7 19.6 21.6 8.6 3.5 12.5 0.5 6.8 0.1 0.6 0.4 0.6 1.5 0.3 0.4 0.2 16.7 0.5 7.7 0.0 0.3 0.8 26.6 29.4 24.4 29.8 29.7 32.4 34.8 36.4 29.2 35.7 33.3 31.5 83.3 35.3 67.6 16.3 64.2 724.2 371.8 48.3 241.9 3.9 244.6 244.5 48.7 130.1 35.6 46.0 0.0 185.0 208.1 83.4 31.3 32.9 9.9 305.3 417.4 74.9 66.7 33.9 18.4 13.2 681.2 605.1 102.4 410.5 51.4 10.8 94.9 402.7 345.7 3.3 8.6 102.5 24.4 500.4 438.5 10.6 129.5 765.6 217.1 37.5 159.0 87.6 61.8 0.5 1.8 19.2 60.9 96.3 102.7 346.5 61.9 74.2 29.8 5.6 157.8 466.2 356.7 1.1 13.3 162.1 800.1 1409.9 159.3 68.2 63.4 359.6 CERS5 "FLJ25304, LASS5, MGC45411, Trh4" ENSG00000139624 "Ceramide synthase 5" Q8N5B7 12 50129289-50167533 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006780, HPA026589" Approved Approved "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear membrane, Endoplasmic reticulum" "HPA006780: , HPA026589: AB_1852727" "unprognostic (1.59e-2)" "unprognostic (9.83e-2)" "unprognostic (5.17e-2)" "unprognostic (3.64e-2)" "unprognostic (3.02e-1)" "unprognostic (2.49e-3)" "prognostic unfavorable (4.63e-5)" "unprognostic (5.56e-2)" "unprognostic (1.65e-2)" "unprognostic (9.26e-2)" "unprognostic (1.88e-3)" "unprognostic (5.67e-2)" "prognostic unfavorable (9.33e-11)" "unprognostic (8.37e-2)" "unprognostic (1.03e-1)" "prognostic favorable (5.76e-5)" "unprognostic (3.26e-1)" 26.2 22.3 27.6 4.8 28.5 5.1 26.6 29.7 48.1 37.2 27.4 24.1 3.0 30.5 12.0 24.0 28.2 6.9 16.2 27.7 29.6 44.1 14.2 22.9 6.1 28.3 28.6 35.1 22.9 9.1 42.3 5.5 28.9 31.2 2.9 5.5 21.5 3.5 5.5 34.1 20.6 4.6 27.5 29.2 21.6 13.8 29.5 7.6 24.8 2.3 3.7 29.5 29.2 29.0 12.1 13.2 17.1 3.5 6.5 3.9 10.6 23.3 6.6 8.0 7.4 36.2 13.9 10.6 20.2 24.4 7.7 7.9 6.1 4.4 6.7 23.4 12.7 6.1 11.2 23.2 16.5 8.0 12.4 19.4 13.9 11.6 6.3 18.7 11.9 10.0 6.1 10.8 8.6 18.7 15.4 45.6 8.2 4.1 7.0 10.7 4.3 12.7 28.7 17.7 5.2 6.9 10.3 9.4 33.6 10.7 13.0 9.9 10.6 17.6 10.2 11.6 8.0 8.1 14.3 11.6 12.8 5.9 8.4 36.3 23.0 42.4 37.0 37.4 28.7 22.0 28.6 28.6 26.8 30.6 20.1 28.9 41.2 39.6 55.1 36.0 37.1 37.1 27.6 28.5 29.7 48.1 27.7 29.6 28.3 28.6 28.9 27.5 29.5 29.0 14.9 19.2 18.4 22.5 17.7 17.3 20.9 29.1 12.0 41.0 11.5 9.8 6.8 14.3 16.5 14.7 20.9 32.9 23.1 8.1 7.9 21.2 0.9 7.7 16.7 17.2 15.6 9.1 47.7 14.0 65.2 21.9 10.7 11.8 15.2 15.0 18.2 4.6 19.0 32.0 56.1 7.9 28.5 17.9 18.3 2.2 16.8 14.3 12.4 20.6 26.6 21.3 24.7 40.2 34.8 19.0 6.8 17.3 12.7 15.5 14.2 7.7 8.6 44.3 32.9 18.2 20.8 7.6 8.1 9.3 14.3 33.7 22.1 15.7 6.7 14.7 CHKA "CHK, CKI" ENSG00000110721 "Choline kinase alpha" P35790 11 68052859-68121444 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 179.6;Early spermatids: 357.3;Late spermatids: 267.3;Oligodendrocytes: 203.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 183.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024153, CAB072803" Approved Approved "Endoplasmic reticulum" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "CAB072803: , HPA024153: AB_1846664" "unprognostic (5.16e-2)" "unprognostic (1.46e-1)" "unprognostic (2.52e-1)" "unprognostic (2.51e-1)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (7.75e-4)" "unprognostic (2.36e-3)" "unprognostic (1.66e-3)" "unprognostic (1.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.99e-1)" "unprognostic (5.97e-3)" "unprognostic (5.00e-2)" "unprognostic (6.06e-2)" "unprognostic (1.82e-1)" "unprognostic (4.73e-2)" 17.0 35.8 49.4 7.1 54.2 33.8 20.9 51.8 57.8 18.3 53.5 25.8 21.6 12.2 20.5 6.2 13.2 10.3 14.5 49.5 50.7 23.9 43.3 17.8 9.0 56.6 53.6 20.1 38.0 8.0 21.6 5.2 61.5 31.0 12.8 21.1 44.9 16.4 8.3 8.7 23.1 5.4 51.0 30.0 40.0 75.5 54.0 5.7 43.6 4.5 5.5 19.4 9.3 71.7 25.6 21.3 24.2 24.1 8.0 6.1 24.5 7.7 13.6 22.5 14.4 92.2 70.5 18.9 27.4 12.4 23.2 16.2 34.4 5.6 18.5 8.7 12.1 23.8 29.6 106.9 22.9 25.6 12.5 11.0 9.4 10.0 4.8 12.3 12.7 11.9 23.1 34.7 12.0 19.4 14.6 68.4 40.1 83.2 14.2 21.3 26.1 54.6 18.1 27.3 17.9 19.6 14.9 74.6 183.8 19.9 31.6 34.4 7.3 14.2 16.3 32.4 10.4 37.0 42.5 34.4 14.6 32.8 13.0 0.0 0.8 6.1 0.1 1.5 0.0 0.7 0.1 0.2 0.9 0.3 0.4 0.2 0.4 1.1 0.9 0.7 0.2 0.2 49.4 54.2 51.8 57.8 49.5 50.7 56.6 53.6 61.5 51.0 54.0 71.7 27.2 44.8 36.6 179.6 10.1 15.8 16.6 6.5 18.2 10.6 49.4 35.7 3.6 35.8 20.2 3.7 33.3 8.2 14.2 48.1 13.7 9.6 357.3 42.7 16.2 13.6 28.1 6.7 89.0 19.3 3.4 9.2 37.2 59.0 19.0 23.4 11.7 19.8 17.6 57.2 63.2 16.3 0.0 28.5 19.4 267.3 6.2 31.0 23.2 59.0 8.5 21.4 2.1 100.0 203.5 18.4 18.0 2.6 10.1 17.3 21.6 4.6 23.1 28.4 0.0 9.6 9.8 121.9 20.7 9.2 10.4 13.0 8.2 16.9 31.7 39.2 CHL1 "CALL, FLJ44930, L1CAM2, MGC132578" ENSG00000134121 "Cell adhesion molecule L1 like" O00533 3 196763-409417 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8" "Cell type enhanced" "Detected in many" "Astrocytes: 223.6;Excitatory neurons: 423.8;Inhibitory neurons: 320.7;Oligodendrocyte precursor cells: 918.4" "Cancer enhanced" "Detected in many" "glioma: 15.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 33 "memory B-cell: 2.7;naive B-cell: 3.7" "Lineage enriched" "Detected in single" 38 "B-cells: 3.7" "Group enriched" "Detected in some" 5 "SK-MEL-30: 91.8;WM-115: 29.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003345, CAB026120" Enhanced "Secreted in brain" NA NA 5800000000 "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB026120: , HPA003345: AB_1078516" "unprognostic (5.54e-2)" "unprognostic (2.08e-1)" "unprognostic (7.45e-2)" "unprognostic (7.14e-3)" "unprognostic (1.16e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-2)" "unprognostic (2.22e-1)" "unprognostic (5.14e-1)" "unprognostic (1.06e-1)" "unprognostic (7.81e-2)" "unprognostic (3.51e-1)" "prognostic favorable (1.21e-6)" "unprognostic (1.11e-1)" "unprognostic (6.07e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" 13.6 4.1 18.6 8.6 33.9 0.3 8.5 2.3 35.5 3.3 0.0 14.7 4.4 3.4 1.6 8.9 2.6 4.8 11.5 35.8 26.7 17.8 0.8 5.1 6.2 12.5 5.3 16.3 1.7 0.5 2.6 0.0 5.7 3.7 7.9 15.9 6.9 6.3 0.3 12.9 6.2 5.4 10.0 3.0 4.0 1.5 10.6 0.7 0.9 1.4 2.9 3.1 5.3 5.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 91.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 29.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 33.9 2.3 35.5 35.8 26.7 12.5 5.3 5.7 10.0 10.6 5.0 4.1 0.0 0.0 223.6 8.8 22.9 0.6 2.8 56.9 1.2 0.6 13.6 18.0 1.5 15.8 11.0 0.0 0.0 0.1 0.0 11.7 0.0 2.0 2.9 0.1 2.3 0.0 0.0 423.8 0.0 0.0 33.5 0.0 1.9 1.3 106.2 1.4 1.3 0.0 1.7 320.7 0.0 0.0 0.3 4.4 1.4 2.8 0.6 3.6 22.5 0.0 58.7 0.0 918.4 11.6 0.2 0.0 0.0 1.4 6.2 0.0 19.7 17.8 2.7 0.0 2.7 11.2 3.0 1.3 15.6 12.1 0.0 1.1 12.4 0.0 0.8 CHPT1 CPT1 ENSG00000111666 "Choline phosphotransferase 1" Q8WUD6 12 101696947-101744140 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 344.4;Late spermatids: 650.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 36.9;eosinophil: 14.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 36.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067643 Approved Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA067643: " "unprognostic (1.59e-3)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.48e-2)" "unprognostic (3.15e-1)" "unprognostic (9.17e-2)" "unprognostic (5.79e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-1)" "unprognostic (4.70e-1)" "unprognostic (5.27e-2)" "unprognostic (1.16e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.72e-1)" "prognostic favorable (7.41e-4)" "unprognostic (1.79e-1)" 39.8 47.7 48.6 17.7 49.1 62.0 102.9 43.8 65.6 50.5 41.9 49.4 88.1 19.2 56.1 24.9 33.4 40.2 91.3 46.1 47.3 73.5 157.4 38.4 20.0 50.0 51.2 18.7 25.0 92.4 12.4 22.8 44.9 35.0 48.9 4.8 130.0 50.0 27.8 28.0 75.7 18.8 50.0 23.5 56.0 28.1 54.4 9.0 38.0 28.3 21.2 32.4 26.2 48.9 11.3 51.2 13.7 29.3 106.6 35.7 38.9 40.2 46.2 39.7 25.5 19.3 7.7 17.3 22.1 55.1 54.3 16.9 83.8 14.2 37.3 26.2 70.1 69.7 25.7 112.6 59.4 34.8 13.5 33.6 4.1 18.0 32.7 59.0 20.0 36.4 102.8 43.1 39.4 27.6 20.8 118.5 36.2 53.8 67.4 15.9 26.8 12.4 17.9 43.4 13.8 10.4 37.2 52.3 103.2 21.4 53.8 23.6 14.7 36.1 18.7 28.5 39.9 24.3 7.9 21.2 28.4 39.7 53.4 36.9 2.2 14.6 0.6 1.7 0.6 4.4 1.2 0.9 2.9 2.6 0.4 0.6 3.1 4.6 2.2 3.7 0.6 0.5 48.6 49.1 43.8 65.6 46.1 47.3 50.0 51.2 44.9 50.0 54.4 48.9 27.1 48.1 27.6 159.6 135.1 37.5 313.3 4.2 21.6 19.3 243.8 76.7 45.3 102.9 13.1 64.4 29.2 123.9 32.6 61.7 70.5 8.1 344.4 17.1 50.2 22.5 21.1 168.6 95.8 13.8 56.1 75.4 69.8 21.0 10.8 15.3 31.1 189.7 56.4 35.3 95.6 53.4 2.0 102.9 55.7 650.9 85.4 81.2 145.9 36.5 27.0 68.1 5.2 65.9 10.2 9.6 113.3 89.1 55.4 172.1 174.1 183.7 4.3 16.0 19.7 88.2 37.8 193.8 43.2 43.1 43.2 60.3 41.3 3.4 90.7 291.6 CIR1 CIR ENSG00000138433 "Corepressor interacting with RBPJ, CIR1" Q86X95 2 174348022-174395712 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 187.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 187.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015784, HPA061442" Approved Supported "Nuclear speckles" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA015784: AB_1846782, HPA061442: AB_2732664" "unprognostic (3.17e-3)" "unprognostic (4.07e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (2.40e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.00e-2)" "unprognostic (4.39e-2)" "prognostic favorable (9.80e-4)" "unprognostic (1.27e-1)" "unprognostic (3.66e-2)" "prognostic unfavorable (1.04e-7)" "unprognostic (2.23e-1)" "unprognostic (1.48e-1)" "unprognostic (8.10e-3)" "prognostic favorable (2.04e-5)" 26.7 23.8 36.3 23.4 38.1 67.3 35.9 38.5 61.1 26.6 39.5 27.7 25.8 27.4 43.5 20.3 28.3 23.4 28.7 36.0 37.3 25.9 27.5 26.7 31.1 36.8 37.0 33.7 24.9 27.4 25.1 29.8 36.6 26.2 26.3 23.6 24.9 26.0 30.7 30.5 26.7 20.7 35.9 35.0 25.5 31.4 36.3 32.3 29.0 25.2 29.5 24.0 24.2 40.1 20.4 11.4 26.5 21.2 36.3 50.4 39.2 32.9 46.5 32.3 39.5 21.5 30.7 14.1 30.3 32.4 28.3 24.0 22.1 23.4 38.6 26.1 29.1 29.4 17.8 34.9 35.1 35.2 26.0 41.7 41.9 35.5 26.5 55.6 32.4 24.9 30.7 30.8 31.0 19.5 44.1 55.6 24.5 33.2 31.6 24.7 38.1 42.2 38.4 32.1 30.7 36.1 22.7 28.7 52.9 45.7 21.6 51.6 33.6 26.1 19.0 24.9 17.3 34.6 31.4 5.2 37.4 18.2 23.3 71.0 33.8 55.9 28.4 31.7 28.4 41.2 32.2 30.5 21.4 40.5 33.4 30.9 187.8 45.3 33.9 39.5 37.2 28.3 36.3 38.1 38.5 61.1 36.0 37.3 36.8 37.0 36.6 35.9 36.3 40.1 82.0 118.6 79.8 30.0 80.8 28.6 52.2 118.6 39.3 51.7 40.6 66.8 61.4 61.5 101.2 42.3 31.3 72.7 116.5 69.1 119.3 67.3 201.5 192.2 79.7 58.7 51.4 102.5 30.4 78.7 58.1 69.9 30.1 79.6 81.6 59.1 75.7 58.6 63.8 45.4 33.7 81.9 85.5 93.0 30.3 43.4 107.2 75.3 33.8 22.5 108.2 85.7 111.2 30.2 37.3 57.7 79.8 82.4 49.1 37.5 91.6 114.0 202.3 56.2 72.3 71.4 72.1 219.5 54.7 25.4 32.0 116.0 80.5 62.6 53.5 45.7 CITED1 MSG1 ENSG00000125931 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1" Q99966 X 72301638-72307187 "Predicted intracellular proteins" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "epididymis: 1473.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 87.4;Breast myoepithelial cells: 47.6;Granulosa cells: 31.0;Late spermatids: 58.4;Paneth cells: 33.8" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 134.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SK-MEL-30: 244.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049051 Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Cytosol "HPA049051: AB_2680612" "unprognostic (7.04e-2)" "unprognostic (3.39e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-3)" "unprognostic (8.81e-2)" "unprognostic (5.67e-4)" "unprognostic (3.40e-1)" "unprognostic (9.55e-2)" "unprognostic (4.60e-3)" "unprognostic (4.38e-2)" "unprognostic (6.33e-3)" "unprognostic (1.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.62e-1)" "prognostic favorable (6.10e-4)" "prognostic favorable (3.95e-4)" "unprognostic (2.99e-2)" 2.3 5.1 13.0 0.3 6.9 0.2 23.1 5.1 12.2 5.9 3.4 1.0 0.7 3.6 1473.6 0.3 1.5 0.0 0.7 6.7 56.2 5.1 0.4 0.6 0.3 8.5 8.8 1.5 1.5 0.0 209.9 0.0 24.5 11.2 0.2 4.5 0.8 3.0 0.4 0.6 1.0 8.1 4.3 0.4 1.0 199.9 30.6 0.2 8.0 0.4 0.1 0.5 1.0 6.2 0.4 0.3 2.2 57.1 2.5 0.0 2.1 0.0 0.5 0.4 0.3 0.1 0.6 0.0 0.2 0.0 0.6 0.0 20.5 1.4 0.1 6.1 8.0 0.9 0.4 0.0 0.0 0.2 10.4 1.1 0.8 0.5 1.0 0.2 0.2 0.2 2.5 0.0 0.4 0.8 0.2 4.4 3.3 0.0 3.6 0.1 3.6 3.2 0.1 0.4 25.8 12.5 0.4 5.1 244.4 0.2 1.4 1.0 0.0 0.2 1.9 0.4 0.8 0.2 0.5 0.2 0.5 0.4 5.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 6.9 5.1 12.2 6.7 56.2 8.5 8.8 24.5 4.3 30.6 6.2 2.2 0.0 0.0 0.0 0.0 0.1 1.0 0.4 0.0 5.6 87.4 47.6 0.4 1.5 0.1 3.7 6.2 0.1 0.3 0.3 0.0 0.1 20.4 0.5 0.8 1.0 1.2 0.0 0.7 0.8 0.1 0.7 0.0 0.3 0.0 31.0 0.4 0.1 0.1 0.0 1.5 0.2 0.0 0.0 0.7 58.4 7.5 0.8 3.6 1.9 0.1 1.7 0.0 0.0 0.1 0.4 33.8 3.0 0.0 19.3 0.7 0.3 0.0 3.8 13.1 1.2 3.2 12.6 6.8 0.0 0.0 0.0 0.1 0.5 0.5 1.0 CLCN7 "CLC-7, CLC7, OPTA2, PPP1R63" ENSG00000103249 "Chloride voltage-gated channel 7" P51798 16 1444934-1475084 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 74.0" "Cancer enhanced" "Detected in all" "melanoma: 42.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043019, HPA043586" Supported NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "HPA043019: AB_10964727, HPA043586: AB_10965322" "unprognostic (2.69e-1)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (5.61e-2)" "unprognostic (1.90e-2)" "prognostic favorable (5.23e-4)" "unprognostic (1.59e-2)" "unprognostic (1.29e-2)" "unprognostic (1.17e-1)" "unprognostic (4.65e-2)" "unprognostic (1.41e-2)" "unprognostic (3.98e-1)" "unprognostic (3.49e-3)" "unprognostic (5.81e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (2.80e-1)" "unprognostic (2.54e-1)" 18.1 37.3 14.4 16.9 14.2 34.3 17.3 12.8 18.0 18.7 18.0 20.0 16.6 20.3 6.3 12.4 17.0 12.3 16.6 14.2 14.1 21.1 22.0 19.1 18.3 17.9 19.2 15.1 21.8 20.8 21.7 12.4 20.7 16.5 7.1 9.2 16.8 12.0 28.0 23.1 22.7 13.2 11.9 27.3 22.3 19.2 18.0 15.6 23.1 8.3 12.1 16.0 11.9 15.8 14.2 36.9 21.0 33.7 41.3 21.5 34.3 18.9 36.4 35.2 41.5 30.8 51.2 16.3 38.6 23.7 73.8 29.4 18.4 21.0 11.4 26.1 31.5 11.6 37.9 30.0 72.4 29.4 45.1 42.9 28.4 32.1 28.5 23.9 23.0 36.3 48.0 29.2 18.5 28.4 21.3 50.6 21.7 9.0 21.8 96.7 13.3 45.2 16.4 18.2 22.5 24.9 30.8 37.5 120.2 11.8 33.6 78.0 26.3 34.9 16.2 39.1 18.4 47.3 32.1 16.5 28.2 54.3 22.6 0.0 1.6 1.2 0.8 2.7 0.3 1.0 0.4 0.4 1.2 1.0 0.2 0.3 0.3 0.3 3.4 1.1 0.1 1.0 14.4 14.2 12.8 18.0 14.2 14.1 17.9 19.2 20.7 11.9 18.0 15.8 12.6 0.0 7.5 25.1 16.5 7.4 5.5 6.3 9.1 45.0 14.5 12.7 4.4 4.3 8.2 20.2 35.5 10.2 12.3 20.4 1.9 16.2 10.2 14.0 14.9 11.1 12.0 8.0 22.3 17.8 8.9 11.0 18.8 17.9 6.3 24.0 16.8 15.6 36.3 74.0 20.6 14.5 4.1 28.3 11.5 8.6 11.5 29.6 39.2 24.4 22.4 27.3 13.4 8.5 17.9 17.9 7.3 8.2 9.3 9.0 14.5 14.7 7.8 28.1 0.0 9.9 11.9 13.5 10.7 5.6 6.8 15.5 9.4 19.4 15.1 5.2 CMC1 "C3orf68, MGC61571" ENSG00000187118 "C-X9-C motif containing 1" Q7Z7K0 3 28241584-28325142 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 418.8;NK-cells: 694.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 162.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043333 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "HPA043333: AB_10797139" "unprognostic (1.16e-1)" "unprognostic (8.01e-3)" "unprognostic (6.90e-3)" "unprognostic (8.88e-2)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (3.81e-2)" "unprognostic (3.64e-1)" "unprognostic (1.26e-1)" "unprognostic (3.80e-3)" "unprognostic (3.09e-1)" "unprognostic (2.30e-2)" "prognostic favorable (6.81e-4)" "unprognostic (3.54e-1)" "unprognostic (8.12e-2)" "unprognostic (4.55e-1)" "prognostic favorable (5.52e-4)" 15.9 18.7 9.4 4.8 9.4 4.9 11.8 9.6 14.3 10.6 9.7 14.7 7.6 10.1 5.3 11.9 11.4 4.0 34.6 9.1 9.8 24.2 24.8 11.5 4.3 9.4 9.4 10.5 11.8 5.0 16.9 6.5 9.6 11.4 4.0 3.2 9.3 4.5 24.8 9.1 9.9 3.4 9.3 12.3 14.7 4.2 9.6 4.1 9.6 13.7 2.9 12.2 11.4 9.5 15.2 24.7 6.8 7.1 18.5 18.5 17.4 20.0 6.1 8.5 8.5 7.3 21.0 13.5 24.8 3.3 14.2 7.1 8.7 18.7 5.1 30.4 21.9 14.5 22.1 16.2 19.1 9.3 10.9 9.9 13.8 8.6 10.8 19.2 10.7 34.0 14.2 19.3 6.9 13.7 13.6 25.1 7.9 15.2 27.0 12.7 7.9 11.0 10.9 6.7 6.7 12.5 14.7 9.1 44.9 9.4 18.8 27.4 12.9 9.1 11.2 13.8 13.1 8.9 22.0 19.7 24.1 20.5 19.2 24.2 21.9 17.1 40.2 28.9 57.7 18.4 25.4 69.6 29.9 17.1 18.8 41.9 6.7 162.2 32.9 30.4 27.2 29.4 9.4 9.4 9.6 14.3 9.1 9.8 9.4 9.4 9.6 9.3 9.6 9.5 51.5 38.5 33.0 26.4 28.3 21.2 38.0 68.6 23.9 16.2 40.0 53.5 202.8 30.0 42.3 31.3 10.4 68.4 418.8 68.2 221.1 61.3 226.4 67.2 38.5 42.1 28.2 128.6 51.5 58.6 42.4 39.4 24.5 42.5 36.7 25.9 50.3 88.7 64.5 3.3 61.2 71.7 67.1 61.7 26.2 31.1 49.4 36.4 30.2 41.2 53.8 37.4 694.1 53.8 63.3 66.1 71.3 39.1 32.7 42.9 56.2 134.4 56.0 25.4 39.5 31.2 71.6 26.3 49.3 28.6 32.8 31.5 222.5 58.2 67.9 42.2 CNIH1 "CNIH, CNIL, TGAM77" ENSG00000100528 "Cornichon family AMPA receptor auxiliary protein 1" O95406 14 54423561-54441391 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002544 Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA002544: AB_2081856" "unprognostic (1.06e-1)" "unprognostic (1.18e-3)" "unprognostic (7.09e-2)" "unprognostic (5.06e-2)" "unprognostic (1.50e-1)" "unprognostic (8.93e-3)" "unprognostic (1.47e-1)" "unprognostic (2.71e-3)" "unprognostic (4.78e-2)" "unprognostic (4.62e-1)" "unprognostic (1.38e-2)" "unprognostic (1.79e-1)" "unprognostic (4.12e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (8.95e-4)" 73.2 61.7 40.2 50.9 42.1 37.2 73.6 45.2 49.5 59.8 58.5 86.9 99.4 49.6 50.8 72.5 67.0 74.4 84.6 42.8 47.2 79.9 232.9 46.7 61.2 44.3 43.4 44.0 41.8 59.8 41.2 58.4 44.8 57.2 95.1 60.3 49.7 57.1 58.9 36.0 85.4 68.2 49.1 33.8 45.4 37.1 41.3 56.2 65.0 95.5 79.0 95.1 39.4 50.7 233.4 141.3 113.8 129.2 301.0 380.9 107.8 276.8 348.6 232.0 264.4 86.5 316.4 289.7 180.2 209.2 141.6 226.5 208.3 200.3 287.5 111.9 124.5 112.1 80.9 152.8 303.6 136.5 90.2 314.4 244.3 217.1 304.0 236.8 221.3 117.7 111.5 95.5 262.4 138.4 151.5 102.9 84.2 266.3 281.3 114.8 191.8 97.3 264.2 171.4 95.5 106.3 163.4 127.8 316.7 104.8 197.5 144.9 143.7 194.7 192.9 165.4 167.8 59.7 138.8 141.2 235.9 115.3 176.5 5.3 84.6 10.7 32.5 66.8 54.8 64.3 57.3 47.0 86.0 55.2 75.1 52.1 20.9 44.0 53.7 48.4 65.1 96.6 40.2 42.1 45.2 49.5 42.8 47.2 44.3 43.4 44.8 49.1 41.3 50.7 41.1 35.3 60.6 14.7 64.9 105.7 86.2 186.1 141.7 41.9 69.2 64.0 85.6 50.1 79.8 46.0 20.9 95.7 48.1 98.8 90.1 89.3 44.4 54.8 57.9 72.3 104.4 65.0 26.9 62.3 123.4 90.3 52.5 32.8 197.3 32.4 70.3 140.0 115.5 67.3 34.8 91.5 99.7 102.8 80.0 17.0 60.0 73.5 83.6 9.4 110.3 59.9 35.0 17.6 22.5 65.6 96.6 65.8 84.0 92.0 149.9 164.7 79.9 45.1 46.0 60.5 68.1 68.7 64.1 144.9 110.0 70.9 69.3 68.4 123.0 91.4 COA5 "C2orf64, FLJ27524, MGC52110, Pet191" ENSG00000183513 "Cytochrome c oxidase assembly factor 5" Q86WW8 2 98599314-98608515 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 180.0;Proximal tubular cells: 175.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057768 Uncertain Supported Mitochondria No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA057768: AB_2683521" "unprognostic (1.00e-1)" "unprognostic (4.19e-2)" "unprognostic (3.85e-2)" "unprognostic (1.67e-3)" "unprognostic (2.61e-2)" "unprognostic (7.11e-2)" "unprognostic (4.69e-2)" "prognostic favorable (2.65e-4)" "unprognostic (1.32e-3)" "unprognostic (3.71e-3)" "unprognostic (8.00e-3)" "unprognostic (3.08e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-1)" "unprognostic (4.93e-2)" "unprognostic (2.50e-1)" "prognostic favorable (1.00e-5)" 14.9 20.9 39.7 10.4 40.9 9.7 18.5 46.0 46.0 19.0 35.6 21.4 14.7 18.5 29.8 11.7 19.2 11.0 21.2 40.1 40.4 26.6 22.8 12.9 16.3 40.7 40.8 21.2 15.6 22.0 23.5 13.4 40.6 19.8 14.4 38.4 15.1 17.6 28.5 16.8 17.7 12.4 40.3 19.4 17.8 12.9 42.6 17.3 22.5 22.0 15.5 18.1 14.1 44.1 18.5 7.9 24.4 17.5 28.1 22.6 20.4 10.6 8.5 11.4 11.8 16.3 15.1 9.6 18.4 8.7 21.7 13.1 21.2 11.5 13.8 24.5 18.5 13.3 15.2 26.0 20.4 13.1 11.6 22.7 23.6 8.1 10.5 19.7 12.0 26.6 18.6 10.8 12.4 14.6 17.2 22.9 16.9 19.8 16.7 10.4 17.2 21.1 24.8 9.9 18.4 23.1 9.1 11.3 27.6 27.4 13.9 26.4 11.1 17.2 15.3 10.4 9.0 17.6 25.0 12.0 21.0 28.0 14.5 20.2 24.9 29.4 23.9 23.5 20.3 23.6 21.0 22.5 24.0 25.3 25.5 25.5 28.0 20.1 25.8 31.2 31.1 22.9 39.7 40.9 46.0 46.0 40.1 40.4 40.7 40.8 40.6 40.3 42.6 44.1 39.5 16.0 28.7 10.4 27.3 10.5 26.3 46.5 28.5 25.5 45.5 62.6 66.6 37.1 32.6 47.8 6.2 36.9 34.8 26.3 180.0 43.4 28.0 52.8 30.4 30.6 27.0 29.4 12.0 24.5 38.8 29.8 21.9 35.6 26.6 33.3 31.8 63.6 52.8 21.9 12.4 37.2 59.0 38.1 12.5 14.9 32.6 30.5 28.4 4.7 41.3 51.4 54.6 8.5 19.1 30.8 29.6 35.0 24.0 34.4 46.1 175.0 49.2 32.0 13.1 23.5 29.7 118.4 33.8 32.5 11.6 32.7 23.5 46.1 33.2 33.6 COL19A1 ENSG00000082293 "Collagen type XIX alpha 1 chain" Q14993 6 69866556-70212468 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.1;lymphoid tissue: 3.2" "Cell type enhanced" "Detected in some" "B-cells: 33.5;Excitatory neurons: 66.6;Inhibitory neurons: 164.2;Oligodendrocyte precursor cells: 39.7" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Region enhanced" "Detected in many" "cerebellum: 9.1" "Group enriched" "Detected in some" 218 "memory B-cell: 14.6;naive B-cell: 31.9" "Lineage enriched" "Detected in single" 299 "B-cells: 31.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.3;RH-30: 11.4;SCLC-21H: 3.7;SH-SY5Y: 2.9;SK-MEL-30: 9.6;WM-115: 9.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA042422 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042422: AB_10794798" "unprognostic (2.65e-2)" "unprognostic (2.55e-1)" "unprognostic (2.71e-1)" "unprognostic (9.24e-2)" "unprognostic (2.26e-2)" "unprognostic (6.20e-2)" "unprognostic (3.17e-1)" "unprognostic (1.10e-3)" "unprognostic (3.41e-1)" "unprognostic (1.28e-1)" "unprognostic (2.76e-1)" "unprognostic (1.62e-2)" "unprognostic (1.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.20e-1)" "unprognostic (3.35e-1)" "unprognostic (8.91e-2)" 0.0 0.1 1.2 1.5 1.6 0.3 0.0 9.1 1.9 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.1 0.1 0.7 2.3 0.1 1.4 0.1 0.0 2.6 0.2 0.2 0.0 0.2 0.0 0.6 0.0 0.3 0.7 0.7 0.6 0.1 0.0 0.7 0.0 0.7 0.0 0.0 1.6 1.1 0.4 0.0 1.1 0.0 0.2 3.2 2.2 0.2 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.4 0.0 0.0 0.0 3.7 2.9 0.0 0.0 9.6 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 31.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 1.6 9.1 1.9 2.3 0.1 0.2 0.2 0.3 0.0 0.0 2.1 0.0 0.0 0.0 11.1 33.5 0.1 0.2 0.0 0.0 4.4 0.1 0.0 2.5 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 66.6 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.7 0.1 0.0 0.0 164.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.8 8.4 0.3 0.1 1.0 39.7 10.6 0.0 0.0 0.0 0.9 0.0 0.0 3.8 0.7 0.1 0.0 11.2 0.4 1.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 CPN1 ENSG00000120054 "Carboxypeptidase N subunit 1" P15169 10 100042193-100081869 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "liver: 81.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 37.2" "Group enriched" "Detected in some" 12 "liver cancer: 26.6;melanoma: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "SK-MEL-30: 141.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.97e-2)" "unprognostic (2.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (6.75e-2)" "unprognostic (2.93e-2)" "unprognostic (5.26e-2)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 81.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 141.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 37.2 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.6 4.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 CREBRF "C5orf41, LRF" ENSG00000164463 "CREB3 regulatory factor" Q8IUR6 5 173056352-173139284 "Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation, Transport, Unfolded protein response" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 68.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 21.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015329 Supported Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA015329: AB_2669192" "unprognostic (8.00e-2)" "unprognostic (2.47e-2)" "unprognostic (1.30e-1)" "unprognostic (3.14e-2)" "unprognostic (5.41e-2)" "unprognostic (1.85e-3)" "unprognostic (1.35e-1)" "unprognostic (6.03e-3)" "unprognostic (1.78e-1)" "unprognostic (1.38e-1)" "unprognostic (2.17e-2)" "unprognostic (4.69e-2)" "prognostic favorable (3.20e-7)" "unprognostic (1.40e-2)" "unprognostic (1.81e-1)" "unprognostic (2.52e-1)" "prognostic favorable (9.30e-4)" 12.9 10.8 9.6 10.4 12.6 68.1 11.1 14.6 11.6 12.2 11.6 9.9 8.4 11.6 11.3 8.7 8.7 9.8 11.2 8.1 12.3 14.5 10.8 11.8 13.2 12.0 11.6 19.0 7.9 15.9 5.8 12.7 12.2 10.0 8.5 11.2 8.8 11.6 8.4 12.1 9.5 10.4 11.0 15.2 8.3 13.4 10.7 12.4 23.2 11.9 10.4 10.3 9.3 14.6 1.2 2.8 2.6 4.1 11.7 15.6 6.1 3.7 18.0 3.4 6.5 3.8 6.3 2.3 8.7 3.8 6.3 1.5 1.2 2.9 4.8 8.4 2.5 1.8 1.9 1.2 9.0 1.4 10.0 9.5 7.3 3.7 9.2 8.3 4.2 2.9 1.6 11.7 4.0 2.3 2.2 2.0 0.8 1.9 1.4 2.1 1.8 3.6 4.8 2.5 2.0 3.0 3.7 1.6 13.6 5.5 1.7 2.6 6.9 5.2 1.7 3.5 1.0 13.0 11.7 4.0 3.8 2.5 1.8 5.6 2.7 6.1 3.6 2.4 3.3 2.9 3.6 3.1 1.4 5.6 4.4 3.6 21.8 1.5 3.3 3.1 3.6 1.8 9.6 12.6 14.6 11.6 8.1 12.3 12.0 11.6 12.2 11.0 10.7 14.6 103.6 51.3 48.4 33.6 95.9 79.2 26.0 19.7 105.3 50.1 68.3 48.1 61.4 44.3 25.9 38.6 68.8 11.6 104.1 50.8 15.6 17.4 5.3 68.9 51.1 66.3 76.7 70.7 57.3 15.7 11.1 67.5 21.4 154.0 48.1 75.2 64.6 39.5 20.4 112.7 64.2 30.3 32.6 96.2 57.7 8.4 51.9 76.7 65.8 70.3 81.7 33.1 55.6 40.2 65.3 17.4 31.8 54.9 78.9 67.6 42.4 23.2 34.8 65.0 59.2 89.8 65.6 74.8 48.0 42.7 92.9 37.4 83.5 26.2 20.5 40.9 CRYZL1 "4P11, QOH-1" ENSG00000205758 "Crystallin zeta like 1" O95825 21 33589341-33643926 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 139.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019120, HPA029399, CAB034129" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cytosol" "CAB034129: AB_2084755, HPA019120: AB_1847264, HPA029399: AB_10600865" "unprognostic (1.54e-1)" "unprognostic (4.69e-2)" "unprognostic (1.53e-1)" "unprognostic (3.18e-2)" "unprognostic (2.55e-1)" "unprognostic (9.19e-2)" "unprognostic (2.73e-1)" "unprognostic (2.57e-3)" "unprognostic (2.90e-2)" "unprognostic (1.08e-1)" "unprognostic (1.76e-1)" "unprognostic (5.86e-2)" "unprognostic (1.59e-2)" "unprognostic (3.59e-2)" "unprognostic (8.16e-3)" "unprognostic (1.59e-1)" "unprognostic (1.28e-3)" 22.4 18.6 23.7 16.4 26.4 22.4 21.1 31.4 33.5 19.2 23.7 28.2 15.0 22.6 19.0 18.8 20.2 16.3 20.0 24.8 25.9 23.5 18.0 16.2 17.7 24.7 26.0 22.0 15.2 22.3 14.2 21.7 25.1 18.3 20.3 29.2 18.0 22.3 19.2 22.9 15.8 21.2 22.5 15.6 17.6 34.0 25.2 18.1 24.5 15.4 14.0 21.0 18.0 34.2 38.0 16.4 45.7 33.8 24.3 35.0 24.0 26.3 37.8 33.0 29.1 24.5 29.0 26.4 23.0 32.5 25.6 20.5 24.6 27.2 30.0 24.6 24.8 49.9 35.5 22.2 38.4 31.0 29.8 32.7 23.4 34.9 27.2 43.1 42.4 42.6 36.8 26.6 31.3 19.3 30.2 31.8 32.3 38.8 21.9 28.5 36.8 36.6 47.1 33.7 19.8 31.2 34.6 17.5 39.7 37.8 34.3 23.1 44.8 26.3 25.3 22.0 20.5 43.4 64.7 29.1 34.4 22.7 30.1 36.1 34.5 36.2 31.7 37.5 34.3 38.2 33.4 29.9 43.3 40.4 43.3 35.3 18.3 47.1 35.6 34.3 29.9 26.8 23.7 26.4 31.4 33.5 24.8 25.9 24.7 26.0 25.1 22.5 25.2 34.2 25.6 32.1 17.3 40.1 25.9 23.6 43.9 58.9 19.9 47.8 22.1 25.1 28.0 31.5 36.0 31.3 31.3 70.4 21.3 20.2 49.0 37.6 90.4 19.6 14.4 29.9 21.0 25.4 42.4 29.1 40.5 28.1 13.3 14.4 65.2 34.5 27.5 15.0 33.5 47.1 47.2 22.5 46.8 26.0 25.7 28.0 44.1 24.6 37.4 26.2 36.1 49.4 41.2 32.2 56.7 28.6 30.3 41.0 11.3 23.3 33.7 44.8 35.0 51.1 19.7 23.7 41.5 139.4 19.4 15.9 21.5 44.6 28.4 27.3 29.4 40.5 CSPG4 "CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2" ENSG00000173546 "Chondroitin sulfate proteoglycan 4" Q6UVK1 15 75674322-75712848 "Predicted membrane proteins" "Angiogenesis, Differentiation, Tissue remodeling" "Developmental protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 55.4" "Group enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 57.3;Sertoli cells: 118.3;Smooth muscle cells: 47.1" "Cancer enhanced" "Detected in all" "melanoma: 74.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 64.7;SK-MEL-30: 146.1;U-138 MG: 92.1;WM-115: 138.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001933, HPA002951, CAB016189, HPA042785, HPA050008" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA 48000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Nucleoplasm "CAB016189: AB_784821, HPA001933: , HPA002951: AB_1854449, HPA042785: AB_10964270, HPA050008: AB_2680991" "unprognostic (5.21e-2)" "unprognostic (2.17e-3)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.56e-2)" "unprognostic (3.58e-1)" "unprognostic (1.09e-2)" "unprognostic (2.11e-2)" "unprognostic (1.07e-1)" "unprognostic (5.00e-2)" "unprognostic (1.63e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (7.60e-6)" "unprognostic (1.23e-2)" "unprognostic (2.04e-2)" "unprognostic (3.21e-2)" "prognostic unfavorable (4.93e-5)" 29.6 1.8 9.0 7.3 7.1 0.0 18.5 6.6 9.3 16.0 1.8 55.4 2.8 34.5 1.4 8.3 15.0 5.6 14.6 7.5 8.2 4.9 0.9 19.4 0.4 11.7 7.8 8.9 2.1 1.2 2.2 15.5 9.7 14.4 2.2 0.1 4.7 11.2 39.6 7.8 15.3 22.7 6.7 5.6 19.1 1.3 7.7 0.6 5.6 10.0 0.3 30.3 12.6 9.8 11.9 0.1 1.0 7.1 1.6 9.8 0.1 64.7 28.6 44.4 28.8 0.1 45.0 0.0 1.5 45.4 6.2 0.6 0.1 0.3 13.6 0.6 0.2 0.0 19.2 0.0 10.0 0.0 0.1 4.8 0.1 13.5 1.5 16.5 0.0 0.0 0.1 0.1 7.6 0.1 0.0 0.2 1.2 0.0 0.3 0.1 4.0 0.1 0.0 0.0 0.1 0.2 1.7 0.1 146.1 1.2 0.9 1.2 0.1 92.1 17.9 3.6 0.8 0.0 0.2 0.0 20.3 0.5 138.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.0 7.1 6.6 9.3 7.5 8.2 11.7 7.8 9.7 6.7 7.7 9.8 4.9 0.0 0.0 1.0 0.0 2.8 0.7 4.7 0.0 1.4 0.1 0.8 11.4 0.0 0.8 1.8 0.0 0.2 0.5 0.1 0.0 0.0 0.6 0.7 0.7 2.7 0.0 0.0 0.4 0.0 0.6 5.9 1.5 0.4 0.0 1.8 1.1 0.2 1.1 0.0 0.2 0.0 0.0 0.0 3.2 0.0 0.3 0.3 12.4 3.7 0.0 0.0 0.0 57.3 0.1 0.0 0.0 0.4 0.0 4.3 0.0 0.1 1.0 0.2 118.3 3.1 47.1 0.0 1.3 0.1 1.8 0.3 0.3 0.1 0.0 0.4 CTH ENSG00000116761 "Cystathionine gamma-lyase" P32929 1 70411218-70439851 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" "Calmodulin-binding, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 122.9;ovary: 34.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 38.0;Hepatocytes: 141.6" "Group enriched" "Detected in all" 5 "liver cancer: 30.0;testis cancer: 8.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 39.7;Karpas-707: 63.8;SK-MEL-30: 85.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021591, HPA023300" Enhanced NA NA 220000 "Cluster 19: B-cells - Humoral immune response" "Cluster 62: Liver - Hemostasis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "HPA021591: AB_1847321, HPA023300: AB_1847322" "unprognostic (3.41e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (2.76e-1)" "unprognostic (7.66e-2)" "unprognostic (2.45e-3)" "prognostic favorable (8.69e-4)" "unprognostic (1.71e-1)" "unprognostic (1.95e-1)" "unprognostic (1.00e-1)" "unprognostic (1.43e-3)" "unprognostic (5.05e-3)" "unprognostic (3.25e-2)" "unprognostic (1.03e-1)" "unprognostic (8.97e-2)" "unprognostic (3.05e-3)" "unprognostic (1.26e-1)" 4.3 12.9 3.4 1.3 3.1 3.4 2.9 3.3 4.0 2.5 4.5 5.1 5.2 2.2 1.6 4.5 3.8 1.8 2.4 3.3 3.6 13.5 122.9 3.1 0.9 3.4 3.7 34.4 17.0 1.4 2.9 1.1 3.4 4.3 6.2 8.1 2.5 2.1 3.6 1.2 5.3 1.3 2.7 1.0 7.4 4.1 3.7 0.6 7.7 2.9 1.3 2.2 1.9 3.2 10.2 1.5 7.1 10.0 8.5 4.8 15.0 4.3 4.1 3.8 15.7 3.2 6.4 5.8 3.4 3.1 9.3 4.9 27.3 3.1 7.2 17.3 5.9 7.0 5.1 9.4 39.7 7.8 1.7 7.5 24.4 7.5 8.8 1.5 3.2 11.9 14.0 63.8 2.2 3.2 2.7 1.9 7.2 4.2 5.9 3.0 3.7 16.2 7.3 0.1 3.9 3.3 6.6 7.7 85.7 13.3 2.6 4.6 1.1 1.2 7.7 5.7 4.1 23.8 15.3 3.1 9.8 16.1 3.1 0.8 0.3 0.1 1.2 0.2 2.1 2.2 1.1 1.7 0.5 1.7 3.2 1.5 0.4 0.2 0.2 0.7 0.3 0.6 3.4 3.1 3.3 4.0 3.3 3.6 3.4 3.7 3.4 2.7 3.7 3.2 2.8 6.4 5.6 16.6 6.7 2.5 8.0 2.2 6.2 9.4 6.2 5.8 1.9 5.7 2.5 5.5 10.4 0.8 5.5 16.1 11.7 1.8 27.2 38.0 6.4 3.3 3.0 7.4 7.8 4.2 1.8 13.6 14.8 19.7 0.0 1.9 3.9 141.6 1.2 0.0 7.4 7.9 2.0 3.5 5.7 5.2 1.2 4.7 19.6 1.9 0.0 4.4 0.0 7.1 4.2 6.4 12.9 4.1 10.8 4.0 11.1 29.2 0.7 11.6 0.0 2.8 17.7 1.4 0.6 4.8 2.0 0.8 11.2 4.5 9.1 3.8 CTNNB1 "armadillo, beta-catenin, CTNNB" ENSG00000168036 "Catenin beta 1" P35222 3 41194741-41260096 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway" Activator "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 539.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000108, CAB001950, HPA029159, HPA029160" Supported Enhanced "Plasma membrane" NA NA 2000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB000108: , CAB001950: , HPA029159: AB_10599619, HPA029160: AB_10600996" "unprognostic (2.47e-1)" "unprognostic (3.48e-2)" "prognostic favorable (7.54e-4)" "unprognostic (1.61e-1)" "unprognostic (9.55e-2)" "unprognostic (1.05e-2)" "unprognostic (3.20e-3)" "unprognostic (2.79e-1)" "unprognostic (1.57e-1)" "unprognostic (1.80e-2)" "unprognostic (1.88e-2)" "unprognostic (9.05e-2)" "unprognostic (1.97e-3)" "unprognostic (1.82e-2)" "unprognostic (1.17e-1)" "unprognostic (2.61e-1)" "unprognostic (9.79e-2)" 130.8 112.2 106.7 98.7 85.3 162.4 194.3 147.8 87.5 179.4 94.7 141.2 136.9 149.4 84.4 113.7 131.0 121.8 109.9 88.1 105.3 106.5 147.9 132.9 81.9 101.3 112.9 173.9 93.3 137.2 84.7 200.0 94.0 132.3 134.5 88.8 110.9 126.3 87.3 99.0 142.9 178.4 104.9 92.5 81.8 59.5 129.4 95.6 140.6 89.9 99.5 158.3 109.3 108.4 161.6 210.0 423.6 242.8 226.9 184.7 333.8 179.6 249.7 288.2 284.3 146.3 224.0 131.7 157.8 314.1 129.0 119.6 315.8 510.0 306.2 123.3 215.7 215.5 261.0 523.7 169.5 121.8 99.1 271.6 226.7 345.5 208.7 235.7 258.1 63.0 153.7 80.3 324.1 161.8 87.3 68.3 397.2 211.0 159.3 64.9 281.9 88.3 177.9 494.8 102.9 172.4 296.2 147.1 809.4 509.8 242.1 248.6 340.8 217.1 163.6 139.3 264.0 50.7 82.7 138.4 221.5 150.5 369.7 4.7 7.3 6.4 9.2 12.3 10.9 7.7 8.6 10.1 11.8 8.0 8.6 9.4 6.6 9.6 12.6 10.0 10.8 5.6 106.7 85.3 147.8 87.5 88.1 105.3 101.3 112.9 94.0 104.9 129.4 108.4 171.7 137.8 179.5 58.1 71.7 213.5 130.1 75.3 116.1 40.7 232.5 168.1 84.7 90.1 119.2 62.5 33.3 318.9 99.0 251.6 35.2 132.2 11.0 90.3 125.9 187.3 93.8 43.8 50.9 78.5 115.6 116.8 53.0 95.5 116.6 137.0 139.2 172.5 115.1 13.5 82.4 145.9 42.7 154.6 228.1 9.5 59.7 161.1 202.7 124.6 98.3 89.2 49.4 70.9 62.9 139.8 249.5 86.9 55.5 128.3 160.3 93.2 96.1 62.0 46.0 175.6 137.3 78.4 40.1 70.9 174.9 539.5 77.0 245.6 189.6 127.9 CTSF "CATSF, CLN13" ENSG00000174080 "Cathepsin F" Q9UBX1 11 66563464-66568879 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 320.9;Muller glia cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SiHa: 23.1;SK-MEL-30: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002141, HPA031431" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 5800000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum, Plasma membrane" "CAB002141: AB_563471, HPA031431: " "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (7.22e-3)" "unprognostic (2.25e-2)" "unprognostic (6.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.76e-2)" "unprognostic (3.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.69e-2)" "unprognostic (9.12e-2)" "prognostic favorable (8.92e-7)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (2.42e-1)" 57.8 70.0 68.1 0.8 76.3 0.3 62.2 74.5 74.0 78.8 90.2 76.7 3.0 89.2 21.9 15.6 70.8 10.0 100.2 63.2 74.2 46.9 66.0 32.9 3.6 75.0 70.3 99.1 31.7 20.0 43.3 3.8 68.4 53.5 3.5 26.2 55.7 17.1 91.9 44.4 29.5 12.2 77.2 25.0 54.3 109.7 71.0 3.0 40.6 27.6 3.0 56.6 58.7 86.6 0.0 17.0 3.1 5.4 14.2 8.6 3.4 13.0 11.4 6.3 2.3 0.0 2.2 0.0 21.3 10.4 0.0 1.2 6.8 2.6 4.8 3.7 0.0 0.5 7.0 0.0 9.9 0.3 4.4 22.3 9.1 0.8 1.6 13.7 3.8 2.0 5.4 1.6 5.2 4.6 0.1 1.7 0.9 3.7 9.7 0.0 0.0 1.5 7.1 0.3 4.3 6.9 23.1 0.3 59.5 0.3 7.4 0.6 3.3 1.8 2.9 1.5 1.2 21.2 0.2 0.0 2.2 0.0 2.9 0.0 0.4 0.3 3.9 0.6 4.1 1.5 3.5 4.6 0.6 1.4 6.4 4.1 0.1 4.6 0.2 0.9 1.3 2.2 68.1 76.3 74.5 74.0 63.2 74.2 75.0 70.3 68.4 77.2 71.0 86.6 36.6 12.8 15.6 31.3 5.9 39.8 62.4 8.5 37.5 107.9 45.3 80.6 57.9 41.5 7.4 36.8 41.7 31.6 9.6 0.6 15.6 13.1 163.3 1.7 22.8 27.2 12.0 11.4 26.5 7.5 9.5 118.1 8.2 5.3 9.5 52.1 56.0 67.8 14.9 134.6 31.3 3.1 18.3 21.5 32.8 320.9 145.7 13.1 156.5 12.2 3.1 196.6 17.5 21.6 29.4 5.9 3.2 121.9 12.9 50.5 1.3 44.7 3.3 77.9 78.9 62.0 45.9 169.6 43.3 3.6 25.3 23.7 9.5 30.7 4.3 32.9 CYP4V2 CYP4AH1 ENSG00000145476 "Cytochrome P450 family 4 subfamily V member 2" Q6ZWL3 4 186191567-186213463 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Monooxygenase, Oxidoreductase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 113.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 103.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 15.2;SK-MEL-30: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029122 Approved Approved "Nuclear speckles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "Nuclear speckles" "HPA029122: AB_10601806" "unprognostic (1.65e-1)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.66e-2)" "unprognostic (5.84e-2)" "unprognostic (2.05e-1)" "unprognostic (6.49e-2)" "unprognostic (9.89e-2)" "prognostic favorable (1.49e-7)" "unprognostic (3.25e-2)" "unprognostic (8.96e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" 7.4 16.4 5.1 5.2 6.8 2.1 5.7 5.6 5.0 8.6 17.9 9.6 16.5 5.6 2.6 5.0 6.1 14.7 9.2 4.8 5.1 33.9 113.5 10.8 5.6 5.3 6.0 5.7 15.6 33.4 3.7 3.5 5.3 8.2 11.9 14.2 7.0 7.5 4.5 1.3 16.7 7.1 5.4 11.2 6.2 3.2 5.6 6.5 17.3 5.0 4.9 6.4 2.3 6.3 3.4 1.8 0.8 0.0 15.2 6.3 0.2 4.4 9.9 1.7 1.9 0.0 13.0 1.1 0.5 3.5 5.9 1.6 1.9 1.7 0.3 6.0 2.2 4.7 0.8 0.5 5.6 2.6 1.9 5.8 0.8 1.9 1.0 5.9 0.1 6.4 1.4 14.3 6.8 2.9 3.6 1.3 1.5 1.6 0.0 3.1 0.7 1.0 7.4 6.1 4.0 4.9 1.1 0.0 27.5 0.3 2.6 4.6 4.1 3.6 0.7 3.5 1.6 0.1 0.0 0.5 10.9 11.0 4.7 0.0 0.6 0.0 1.8 1.9 1.0 0.4 1.4 1.8 0.7 1.0 1.3 1.3 0.0 0.8 3.1 1.3 1.1 0.9 5.1 6.8 5.6 5.0 4.8 5.1 5.3 6.0 5.3 5.4 5.6 6.3 9.0 6.4 11.5 31.3 13.8 2.5 4.5 5.1 9.6 33.6 9.3 7.2 18.8 42.9 8.7 14.7 31.3 2.0 9.6 14.7 9.8 24.2 2.7 6.7 5.1 7.7 16.9 16.4 15.4 22.4 2.1 14.2 12.8 7.6 7.0 6.5 8.9 103.7 13.5 5.0 23.4 16.5 2.0 14.8 6.0 2.1 5.0 11.3 3.6 6.5 3.5 52.2 4.1 15.6 11.0 9.6 9.0 6.4 12.3 3.8 47.2 28.5 11.9 27.4 0.0 10.1 10.6 8.9 6.3 6.8 3.1 1.0 17.2 6.7 10.5 5.7 CYTH3 "ARNO3, cytohesin-3, GRP1, PSCD3" ENSG00000008256 "Cytohesin 3" O43739 7 6161776-6272644 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 66.5;Inhibitory neurons: 96.5;Microglial cells: 57.1" "Cancer enriched" "Detected in all" 5 "melanoma: 47.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "WM-115: 102.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013979 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA013979: AB_1855799" "unprognostic (6.58e-2)" "unprognostic (1.37e-2)" "unprognostic (1.65e-2)" "unprognostic (5.75e-3)" "unprognostic (1.27e-3)" "unprognostic (1.27e-2)" "unprognostic (2.32e-2)" "unprognostic (2.63e-1)" "unprognostic (8.94e-2)" "unprognostic (1.81e-2)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (2.54e-2)" "unprognostic (1.73e-2)" "unprognostic (2.20e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (2.63e-5)" 28.8 9.5 16.9 5.4 17.7 7.7 26.5 16.3 20.9 16.4 11.8 18.3 16.5 17.5 6.6 14.0 15.6 11.8 28.5 18.5 15.3 14.2 4.1 19.7 5.4 14.4 15.5 13.9 7.5 11.5 9.8 31.7 15.4 10.2 6.9 5.7 11.9 8.6 15.2 21.6 16.7 12.1 14.2 10.9 13.9 18.6 16.6 5.8 27.7 19.7 4.7 13.8 15.9 17.5 64.7 16.1 15.0 10.4 68.4 80.0 21.2 37.4 32.3 36.1 34.2 25.0 31.3 8.7 22.1 75.5 46.4 59.5 10.4 27.1 23.8 0.6 14.8 2.4 19.8 3.2 32.4 2.7 4.0 57.0 12.1 19.3 27.6 16.2 6.4 12.6 10.3 1.4 26.7 10.6 2.2 11.5 10.4 8.6 21.5 11.5 40.0 5.0 28.0 7.7 9.6 18.4 23.2 79.7 67.0 12.7 4.8 18.1 23.3 24.6 64.4 26.9 23.2 2.9 1.1 9.1 7.9 6.9 102.8 0.3 0.2 0.0 0.9 0.0 2.5 0.1 0.4 1.0 0.1 0.2 0.0 0.6 0.1 1.5 0.2 0.8 0.3 0.2 16.9 17.7 16.3 20.9 18.5 15.3 14.4 15.5 15.4 14.2 16.6 17.5 40.1 16.0 5.8 14.7 3.1 15.2 2.1 1.8 4.0 6.5 9.2 7.5 17.4 2.8 3.2 3.7 8.4 15.4 8.7 9.7 5.9 4.1 14.1 9.4 10.2 14.6 3.0 2.1 66.5 2.8 9.1 24.0 8.2 15.9 12.7 15.8 18.5 1.4 11.9 15.2 96.5 5.5 4.1 4.1 10.9 16.7 16.4 5.9 32.0 57.1 1.9 10.8 3.1 23.1 10.8 10.0 5.4 13.2 4.4 3.9 14.6 1.4 3.7 2.0 39.5 6.1 39.2 24.3 11.2 7.0 11.4 15.2 10.2 10.9 7.1 2.1 DAAM2 KIAA0381 ENSG00000146122 "Dishevelled associated activator of morphogenesis 2" Q86T65 6 39792298-39904877 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 245.9" "Group enriched" "Detected in many" 5 "Astrocytes: 275.6;Oligodendrocytes: 449.8;Sertoli cells: 151.2" "Group enriched" "Detected in all" 5 "glioma: 15.0;melanoma: 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 54.9;JURKAT: 30.4;LHCN-M2: 55.8;SK-MEL-30: 68.7;WM-115: 26.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051300, HPA054630" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Vesicles, Cytosol" "HPA051300: AB_2681430, HPA054630: AB_2682549" "unprognostic (7.53e-2)" "unprognostic (6.02e-3)" "unprognostic (4.49e-2)" "unprognostic (7.93e-2)" "unprognostic (8.24e-2)" "unprognostic (4.28e-2)" "unprognostic (2.43e-2)" "unprognostic (1.05e-3)" "unprognostic (1.33e-1)" "unprognostic (5.89e-2)" "unprognostic (2.17e-1)" "unprognostic (5.24e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (2.67e-2)" "unprognostic (8.54e-2)" "unprognostic (7.94e-2)" "unprognostic (8.54e-4)" 33.7 22.5 179.4 9.0 229.4 1.8 23.3 175.8 159.3 15.7 65.1 18.9 9.8 14.0 10.4 36.6 18.5 7.4 13.5 144.0 170.5 9.3 4.8 12.4 3.6 234.8 195.8 10.0 7.5 4.1 5.1 12.2 205.0 11.0 8.7 1.6 7.6 21.7 38.3 8.5 20.9 18.3 194.3 40.2 18.9 12.3 187.7 2.5 13.1 38.1 2.3 9.9 11.3 245.9 0.1 0.0 5.8 0.1 12.2 0.3 0.2 9.8 13.1 2.2 1.2 0.9 0.0 0.1 0.5 14.7 4.5 0.1 0.0 0.0 0.8 0.0 2.4 0.0 0.0 0.1 8.8 0.0 0.1 54.9 0.0 0.3 0.0 15.6 0.0 30.4 0.0 0.1 55.8 0.2 1.5 0.1 1.6 3.1 0.1 0.0 10.0 8.1 0.0 0.0 2.0 2.3 0.0 0.7 68.7 11.7 0.0 0.1 0.6 20.8 6.0 0.2 0.3 0.0 0.0 0.0 0.2 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 179.4 229.4 175.8 159.3 144.0 170.5 234.8 195.8 205.0 194.3 187.7 245.9 11.2 9.6 12.2 275.6 0.1 1.8 0.9 0.0 0.0 1.3 1.5 1.5 2.5 1.5 3.8 0.0 0.0 0.5 0.1 0.0 0.0 0.5 3.8 1.2 10.4 9.0 0.0 2.7 1.4 3.3 0.5 11.8 0.5 2.3 0.0 1.9 2.5 1.2 0.2 0.0 5.8 0.0 0.0 31.5 2.4 6.4 23.6 6.2 8.8 21.5 0.0 5.8 1.0 8.5 449.8 0.3 0.0 22.2 0.0 0.8 0.0 0.1 1.5 1.6 151.2 12.7 48.8 1.0 1.9 0.4 1.1 0.3 0.7 55.9 0.0 1.2 DAZ2 "MGC126442, pDP1678" ENSG00000205944 "Deleted in azoospermia 2" Q13117 Y 23219434-23291356 "Disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 25 "stomach 1: 14.3;testis: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SK-MEL-30: 1.8" HPA047113 Approved NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA047113: AB_2679936" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 14.3 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DCT TYRP2 ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 107.4" "Cell type enriched" "Detected in some" 23 "Melanocytes: 3552.1" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 272 "SK-MEL-30: 257.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" 0.4 0.4 0.6 0.0 1.0 0.1 3.0 0.4 0.7 0.2 0.2 0.3 0.0 0.3 0.9 0.0 0.9 0.1 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.6 0.6 0.4 0.4 0.0 1.6 0.0 0.5 0.3 0.0 0.9 1.5 0.3 0.4 107.4 0.1 0.1 0.6 0.1 0.1 0.6 0.6 0.5 0.2 0.1 0.0 0.2 0.3 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 257.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.7 0.6 0.6 0.6 0.6 0.5 0.6 0.6 0.5 0.0 0.0 0.0 23.5 0.0 152.3 0.1 0.0 0.0 1.0 0.3 0.5 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.5 0.1 1.2 0.0 0.0 16.1 0.2 0.0 1.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 25.5 23.8 0.9 0.0 3552.1 1.9 0.0 3.5 0.0 6.6 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 1.0 0.5 0.8 0.0 33.4 0.0 0.9 0.1 0.0 0.0 DEPDC7 ENSG00000121690 "DEP domain containing 7" Q96QD5 11 33015876-33033582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 29.0;kidney: 19.6;liver: 74.0;testis: 28.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 34.8;Early spermatids: 153.3;Extravillous trophoblasts: 47.0;Proximal enterocytes: 33.2;Spermatocytes: 42.3" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 53.7;RH-30: 40.1;SiHa: 37.3;SK-MEL-30: 34.4;U-2197: 34.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA015800 Approved Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoli "Nucleoplasm, Cytosol" "HPA015800: AB_1847610" "unprognostic (2.34e-1)" "unprognostic (5.57e-2)" "unprognostic (1.27e-1)" "unprognostic (2.27e-1)" "unprognostic (2.66e-2)" "unprognostic (7.26e-2)" "prognostic favorable (7.26e-4)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (1.17e-3)" "unprognostic (8.99e-2)" "unprognostic (1.89e-2)" "unprognostic (9.30e-2)" "unprognostic (8.09e-3)" "unprognostic (2.64e-1)" "unprognostic (2.94e-2)" 0.6 0.8 2.5 1.9 3.2 1.8 0.9 2.9 3.7 2.8 2.7 4.6 24.6 1.0 2.2 4.4 0.9 4.4 1.1 2.6 2.7 19.6 74.0 0.9 0.7 3.2 2.7 1.6 3.8 2.3 0.8 1.5 3.0 1.9 5.1 0.1 2.0 1.5 4.9 6.0 29.0 1.7 2.8 0.3 3.0 28.2 2.7 2.9 0.5 0.9 1.5 1.2 3.4 4.9 9.4 5.2 7.3 3.3 3.8 3.6 4.9 16.2 5.4 9.8 13.0 13.5 0.9 0.0 3.7 16.2 4.5 9.4 10.8 3.8 11.5 0.0 14.9 2.5 16.1 19.3 3.2 9.1 10.9 4.6 5.7 5.7 4.2 5.3 0.0 0.0 6.2 0.0 53.7 1.0 0.0 14.6 4.8 7.7 0.0 0.0 40.1 0.1 3.2 1.3 1.6 4.2 37.3 6.6 34.4 5.1 1.7 4.7 0.0 6.3 10.4 34.1 10.6 0.0 0.0 0.1 2.3 0.0 31.5 4.1 0.5 6.7 0.2 0.1 0.0 0.0 0.4 0.2 3.2 0.0 1.9 2.1 0.0 2.4 0.0 1.2 0.0 0.4 2.5 3.2 2.9 3.7 2.6 2.7 3.2 2.7 3.0 2.8 2.7 4.9 0.2 0.0 0.0 1.0 0.0 34.8 12.8 4.5 12.5 0.0 0.2 0.6 0.1 1.5 0.9 0.0 0.0 0.5 0.5 6.0 3.9 0.9 153.3 0.2 0.2 0.3 3.5 3.2 0.1 0.6 47.0 1.6 0.0 0.1 2.5 0.1 1.4 22.6 3.1 0.0 0.4 2.4 0.0 0.6 9.5 16.3 1.5 1.7 1.8 3.7 1.2 0.0 0.0 3.5 10.4 0.8 0.6 1.2 0.1 2.4 33.2 18.4 0.9 0.0 0.0 4.5 1.4 42.3 6.5 6.6 7.4 1.5 0.7 0.2 2.4 1.6 DERL2 "CGI-101, derlin-2, F-LAN-1, F-LANa, FLANa" ENSG00000072849 "Derlin 2" Q9GZP9 17 5471254-5486811 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 259.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037287, HPA048957, HPA056551" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "CAB037287: AB_1078641, HPA048957: AB_2680570, HPA056551: AB_2683171" "unprognostic (2.54e-1)" "unprognostic (5.30e-2)" "unprognostic (5.83e-2)" "prognostic favorable (7.26e-4)" "unprognostic (1.51e-2)" "unprognostic (4.70e-2)" "unprognostic (1.36e-1)" "unprognostic (2.63e-1)" "unprognostic (2.17e-1)" "unprognostic (1.12e-3)" "unprognostic (1.73e-3)" "unprognostic (5.23e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (3.73e-1)" "unprognostic (2.91e-2)" 14.5 18.8 5.7 16.4 6.0 33.9 12.9 6.3 7.6 13.1 7.0 12.9 14.9 12.8 29.6 15.3 14.0 17.3 10.2 5.4 6.2 14.0 28.0 11.3 18.2 6.4 6.4 12.8 28.5 14.7 12.1 13.4 6.6 14.0 12.3 8.1 28.3 11.4 10.6 10.1 17.5 12.4 6.2 15.1 15.5 24.4 6.1 10.8 24.6 4.9 15.4 14.9 11.1 7.6 32.0 40.4 18.8 31.7 31.5 23.6 24.0 44.5 36.1 30.0 36.4 27.8 27.9 22.0 39.2 28.5 33.6 35.0 13.2 25.7 29.9 29.3 27.6 10.8 25.8 30.0 43.4 8.1 25.2 22.0 21.0 40.6 34.9 26.4 31.4 22.4 12.0 37.5 40.9 16.5 17.3 12.3 18.2 20.7 16.0 20.8 26.6 16.3 32.5 16.2 7.9 23.2 27.1 18.5 47.6 20.6 24.8 11.8 23.9 35.4 23.9 21.8 43.3 26.0 31.4 20.0 37.0 20.1 28.4 71.9 62.6 77.0 64.6 70.4 67.2 66.5 61.2 68.7 48.2 65.5 48.3 59.3 59.9 60.4 56.4 69.2 81.0 117.5 5.7 6.0 6.3 7.6 5.4 6.2 6.4 6.4 6.6 6.2 6.1 7.6 36.1 12.8 23.9 12.4 46.4 34.3 50.5 157.7 27.9 17.7 48.4 48.5 31.3 35.8 82.7 44.1 22.9 70.6 70.5 28.1 15.6 79.9 259.2 32.5 41.7 35.7 18.5 35.3 8.1 89.7 103.6 51.3 22.4 41.6 49.4 38.8 30.4 57.5 74.5 11.8 9.0 37.2 89.5 33.6 44.8 63.4 43.8 37.8 46.2 6.5 64.7 35.1 48.4 6.6 16.2 86.7 25.2 35.3 119.9 68.7 37.1 50.4 55.6 24.8 59.2 33.9 54.3 126.4 45.4 26.2 31.1 96.2 47.7 45.8 30.4 62.8 DET1 FLJ10103 ENSG00000140543 "DET1 partner of COP1 E3 ubiquitin ligase" Q7L5Y6 15 88494440-88546681 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA048873 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA048873: AB_2680541" "unprognostic (9.21e-2)" "unprognostic (1.83e-1)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (3.17e-1)" "unprognostic (1.86e-1)" "unprognostic (1.20e-2)" "unprognostic (6.64e-2)" "unprognostic (1.84e-1)" "unprognostic (4.01e-2)" "unprognostic (1.52e-1)" "unprognostic (4.00e-2)" "unprognostic (2.82e-3)" "unprognostic (2.62e-2)" "unprognostic (1.20e-1)" "unprognostic (8.69e-2)" "unprognostic (4.67e-2)" 3.7 5.2 2.5 2.0 2.8 1.2 3.6 2.7 2.7 6.0 3.2 4.2 3.5 6.7 5.4 2.2 5.6 3.0 5.6 2.5 2.6 3.2 2.7 2.1 2.9 2.7 2.5 10.3 3.6 3.7 3.7 3.5 2.8 4.1 3.2 5.0 4.1 3.8 9.7 2.6 3.2 5.5 2.4 2.5 3.4 1.5 2.6 5.6 4.1 11.7 3.0 4.5 3.3 3.2 1.7 6.2 8.6 6.0 3.4 6.0 1.1 5.4 6.1 4.5 5.1 1.0 4.8 3.3 4.1 7.3 4.5 2.4 8.7 1.3 3.9 0.2 5.9 6.9 3.1 1.5 6.7 2.5 1.1 5.0 5.9 1.9 6.9 4.4 3.8 2.9 8.5 3.8 6.7 2.6 3.2 2.8 3.6 2.6 1.8 4.2 6.9 3.8 2.4 5.3 3.0 4.9 6.5 2.0 14.9 5.6 2.9 5.2 3.0 5.1 3.7 4.8 5.4 2.3 1.4 2.1 5.4 4.3 4.5 0.0 2.3 1.6 2.2 3.4 1.4 1.8 1.7 1.9 3.7 2.2 2.6 1.9 0.3 1.4 2.3 1.9 2.4 1.3 2.5 2.8 2.7 2.7 2.5 2.6 2.7 2.5 2.8 2.4 2.6 3.2 3.5 3.2 2.7 6.8 3.5 0.6 2.0 3.7 4.6 11.5 4.3 3.8 2.3 1.5 2.1 3.7 10.4 7.2 1.7 2.1 1.9 3.4 1.2 3.4 6.1 2.3 3.0 5.5 5.7 3.9 6.3 4.9 2.0 2.4 0.0 10.6 2.2 2.8 4.4 6.7 6.8 2.7 2.0 1.6 2.2 0.6 4.4 2.5 3.6 3.7 4.7 7.1 2.1 6.0 9.5 3.1 1.0 3.8 1.6 1.5 3.1 2.6 3.1 7.9 0.0 5.6 4.5 8.1 9.9 1.5 1.3 4.1 2.7 8.4 3.3 1.4 DFFB "CAD, CPAN, DFF-40, DFF40" ENSG00000169598 "DNA fragmentation factor subunit beta" O76075 1 3857267-3885429 "Predicted intracellular proteins" Apoptosis "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 4.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 45.9;Extravillous trophoblasts: 29.5;Oligodendrocytes: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004328, HPA052904" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli Nucleoplasm "CAB004328: AB_626776, HPA052904: AB_2681985" "unprognostic (2.98e-1)" "unprognostic (5.09e-2)" "unprognostic (4.37e-2)" "unprognostic (1.52e-3)" "unprognostic (6.12e-2)" "unprognostic (1.83e-2)" "unprognostic (1.38e-2)" "unprognostic (1.28e-3)" "unprognostic (2.66e-2)" "unprognostic (1.79e-1)" "unprognostic (7.82e-3)" "unprognostic (4.07e-1)" "unprognostic (1.90e-2)" "unprognostic (9.86e-3)" "unprognostic (3.39e-1)" "unprognostic (2.27e-1)" "prognostic favorable (6.29e-5)" 1.3 1.1 0.6 1.2 0.7 1.0 1.1 0.5 0.9 1.7 0.0 1.5 4.6 1.6 0.0 0.8 1.3 1.4 0.7 0.7 0.5 0.7 0.4 1.0 1.6 1.5 0.9 1.7 2.4 0.5 0.6 1.3 0.7 0.8 0.8 0.2 1.3 0.7 0.5 0.6 2.0 0.4 0.4 1.9 1.2 0.4 0.6 1.2 0.8 0.5 0.9 1.4 1.0 1.5 3.2 3.3 2.0 4.7 0.6 1.6 1.1 2.7 1.2 4.1 2.8 2.6 2.8 2.6 2.2 0.5 0.8 1.7 0.7 3.2 0.2 9.0 9.7 10.7 1.2 3.2 3.3 8.7 7.9 0.4 0.8 2.4 1.9 0.8 4.1 7.5 7.4 1.6 0.1 1.8 6.1 4.8 2.2 3.9 7.4 4.9 1.2 4.4 1.3 0.6 3.3 5.1 2.3 6.5 10.7 0.0 1.1 3.8 4.1 1.5 1.1 6.5 2.5 2.9 4.6 5.4 1.2 9.0 2.0 3.6 3.7 5.0 3.4 3.8 2.0 2.1 2.5 3.1 5.1 1.0 2.1 3.2 1.2 2.3 7.4 0.0 4.7 2.9 0.6 0.7 0.5 0.9 0.7 0.5 1.5 0.9 0.7 0.4 0.6 1.5 3.3 3.2 4.6 4.2 3.0 0.6 1.0 1.4 1.8 5.5 1.9 2.7 1.3 2.8 1.7 1.8 45.9 3.5 7.3 1.6 1.9 1.9 1.4 3.3 4.6 3.1 2.4 2.5 17.0 1.6 29.5 3.2 1.5 2.5 0.0 4.6 2.5 1.8 2.9 15.2 18.0 4.2 0.0 5.4 1.4 1.2 1.2 3.7 0.0 8.4 2.5 3.9 15.5 5.5 22.7 1.8 1.5 4.9 3.1 0.6 5.0 2.4 1.1 17.9 0.0 1.7 3.2 1.7 2.5 1.7 0.3 1.4 6.0 3.3 4.4 0.7 DHRS11 "MGC4172, SDR24C1" ENSG00000278535 "Dehydrogenase/reductase 11" Q6UWP2 17 36591879-36600804 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "intestine: 216.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.3;Distal enterocytes: 317.3;Paneth cells: 154.2;Proximal enterocytes: 527.9;Undifferentiated cells: 148.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041226, HPA048236, HPA053623" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" NA NA 42000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 56: Intestine - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Golgi apparatus" "HPA041226: AB_2677372, HPA048236: AB_2680322, HPA053623: AB_2682209" "unprognostic (2.00e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-2)" "unprognostic (3.74e-1)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (1.80e-2)" "unprognostic (3.67e-1)" "unprognostic (5.94e-2)" "unprognostic (1.33e-2)" "unprognostic (4.11e-2)" "prognostic favorable (3.24e-4)" "unprognostic (1.45e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" 10.0 10.5 6.9 5.4 7.9 4.4 10.9 6.7 9.8 9.5 9.0 74.3 216.0 5.7 1.9 14.6 7.3 2.4 17.2 8.6 9.0 21.9 14.8 4.3 2.4 7.4 7.5 5.1 15.4 9.5 13.3 2.0 7.9 8.0 57.1 22.4 10.3 4.5 16.7 14.4 177.0 6.3 6.6 4.7 11.7 17.0 8.2 2.1 11.9 9.9 3.6 6.8 10.5 7.7 13.9 10.0 3.6 13.8 1.2 2.5 10.6 3.8 2.6 11.9 10.7 22.2 10.1 0.8 1.9 4.0 4.8 13.9 11.5 6.7 10.5 7.1 15.2 3.7 10.1 35.6 5.5 3.0 1.2 2.2 7.3 8.6 6.5 1.9 8.8 11.2 36.1 9.3 5.9 12.5 12.6 5.5 4.5 14.2 0.4 15.2 12.8 22.0 9.9 11.4 10.4 4.9 16.0 12.9 33.3 6.6 19.1 3.6 4.8 1.6 18.2 7.6 10.0 14.1 16.7 4.4 6.5 9.3 5.5 0.1 0.1 0.4 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.0 6.9 7.9 6.7 9.8 8.6 9.0 7.4 7.5 7.9 6.6 8.2 7.7 9.1 0.0 1.5 4.2 3.3 4.2 8.9 2.8 4.0 20.7 14.6 13.3 9.6 2.8 2.4 7.3 129.3 7.9 1.4 317.3 58.7 10.7 22.9 10.2 5.0 6.7 12.1 31.5 8.2 11.4 4.7 3.4 8.6 6.8 0.0 5.3 5.3 12.7 3.5 16.8 9.6 72.2 2.0 1.9 4.2 30.5 4.1 2.6 19.6 2.8 3.6 15.8 1.0 4.0 2.0 7.5 154.2 5.3 9.1 11.7 527.9 43.1 3.8 71.0 0.0 5.9 5.9 27.7 6.5 12.0 6.0 7.0 3.1 9.3 148.5 15.2 DIPK1C "C18orf51, FAM69C" ENSG00000187773 "Divergent protein kinase domain 1C" Q0P6D2 18 74434775-74457944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 28.6;choroid plexus: 11.3;retina: 16.5" "Cell type enriched" "Detected in single" 27 "Cardiomyocytes: 22.1" "Group enriched" "Detected in some" 18 "glioma: 11.1;melanoma: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "SK-MEL-30: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048928 Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA048928: AB_2680560" "unprognostic (6.35e-2)" "unprognostic (1.13e-2)" "unprognostic (8.09e-2)" "unprognostic (3.32e-2)" "unprognostic (4.08e-2)" "unprognostic (3.19e-1)" "unprognostic (1.43e-2)" "unprognostic (1.10e-1)" "unprognostic (3.31e-1)" "unprognostic (8.97e-2)" "unprognostic (2.43e-1)" "unprognostic (4.10e-2)" "unprognostic (1.91e-4)" "unprognostic (2.16e-1)" "unprognostic (6.73e-2)" "unprognostic (3.23e-2)" "unprognostic (4.40e-3)" 0.3 0.1 19.6 0.0 26.4 0.0 0.3 21.4 25.8 1.6 11.3 1.4 0.0 0.2 0.1 0.1 0.2 0.4 8.4 18.6 20.6 0.1 0.3 0.0 0.0 19.7 24.4 0.0 0.1 0.0 0.3 0.1 19.2 0.4 0.1 16.5 0.3 0.6 1.1 4.2 0.3 0.1 16.5 0.1 1.5 6.8 26.0 0.7 0.0 2.0 0.0 0.1 0.4 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 26.4 21.4 25.8 18.6 20.6 19.7 24.4 19.2 16.5 26.0 28.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DLL3 SCDO1 ENSG00000090932 "Delta like canonical Notch ligand 3" Q9NYJ7 19 39498895-39508481 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.7;choroid plexus: 2.3;pituitary gland: 3.4;testis: 1.4" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 24.6;Spermatogonia: 39.5" "Group enriched" "Detected in many" 11 "glioma: 29.2;melanoma: 15.5;testis cancer: 8.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.6;naive CD8 T-cell: 1.4" "Group enriched" "Detected in many" 13 "B-cells: 2.6;T-cells: 1.4" "Cell line enriched" "Detected in some" 6 "SK-MEL-30: 83.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024559, HPA056533" Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA024559: , HPA056533: " "unprognostic (2.52e-1)" "unprognostic (3.81e-1)" "unprognostic (3.13e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.85e-2)" "unprognostic (1.41e-2)" "unprognostic (1.65e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (6.58e-2)" "unprognostic (1.06e-2)" "unprognostic (4.20e-2)" "unprognostic (3.82e-4)" "unprognostic (4.94e-2)" "unprognostic (5.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.97e-1)" 0.0 0.0 5.1 0.1 5.7 0.0 0.0 3.1 5.6 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 4.7 0.0 0.0 0.0 0.1 4.9 4.7 0.2 0.0 0.5 3.4 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.1 0.0 1.4 4.6 0.0 0.1 0.0 0.1 0.0 0.0 5.4 0.1 3.9 0.9 2.0 0.0 0.0 0.6 1.1 0.0 0.7 0.2 0.5 0.9 0.1 3.7 0.0 1.5 0.1 2.3 1.0 0.2 1.2 6.0 0.2 0.1 0.3 0.3 1.0 4.6 0.0 0.0 0.1 0.1 0.1 0.1 4.3 1.1 0.1 0.3 0.0 0.2 0.0 0.7 0.0 6.2 0.6 0.2 0.2 0.2 0.2 13.6 14.1 2.9 0.1 83.7 0.3 0.0 0.2 0.0 0.0 2.6 0.1 1.0 1.4 0.0 0.9 0.1 0.5 2.3 0.0 0.0 0.0 0.3 0.0 0.1 2.6 0.1 0.5 0.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 5.1 5.7 3.1 5.6 4.7 4.7 4.9 4.7 4.2 4.4 4.6 5.4 0.3 0.0 0.0 0.3 1.1 0.3 0.3 0.4 0.0 0.5 1.3 4.7 0.5 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.7 0.6 0.1 0.7 0.2 3.0 0.0 1.7 0.6 0.6 1.0 0.5 0.3 0.0 1.7 0.0 0.0 0.3 0.0 3.4 0.3 0.0 0.0 0.0 2.2 1.2 0.1 1.8 0.0 0.0 0.9 0.0 24.6 0.5 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.7 6.6 0.0 0.6 6.5 39.5 0.2 0.1 0.3 0.5 1.7 0.0 0.1 DNASE2 "DNL, DNL2" ENSG00000105612 "Deoxyribonuclease 2, lysosomal" O00115 19 12875209-12881466 "Enzymes, Predicted intracellular proteins" Apoptosis "Developmental protein, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 226.7;Paneth cells: 125.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066185 Enhanced "Intracellular and membrane" NA NA 560000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA066185: AB_2685632" "unprognostic (9.62e-2)" "unprognostic (2.19e-3)" "unprognostic (8.97e-2)" "unprognostic (7.45e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (5.42e-2)" "unprognostic (4.85e-2)" "unprognostic (1.40e-1)" "unprognostic (5.12e-2)" "unprognostic (4.37e-2)" "unprognostic (2.58e-2)" "unprognostic (4.69e-2)" "unprognostic (3.57e-1)" "unprognostic (1.98e-1)" 27.0 26.7 17.1 24.0 17.5 9.6 23.3 17.2 19.1 22.7 19.7 24.7 23.7 25.1 29.5 18.9 25.3 25.3 22.7 16.5 17.6 19.2 36.0 37.7 42.2 18.7 18.2 26.1 41.7 43.1 23.8 20.6 19.4 27.7 19.2 5.6 33.0 26.1 19.7 29.2 22.7 22.0 19.3 26.2 30.0 5.9 17.8 20.8 38.7 13.1 26.5 24.3 19.9 23.0 63.7 36.3 2.9 80.8 86.8 46.2 55.0 34.4 87.2 33.2 79.6 3.8 43.6 27.9 97.3 54.9 73.0 71.8 30.7 33.2 16.2 89.8 41.0 13.1 36.8 17.5 68.3 26.5 119.8 46.5 74.5 24.8 36.7 80.2 50.2 42.4 14.0 112.1 20.3 82.7 27.3 14.1 6.1 66.3 60.8 17.1 14.2 64.3 32.9 29.7 17.3 28.6 46.1 65.8 123.5 11.8 98.5 23.4 32.5 67.8 21.4 70.3 31.1 139.9 153.6 35.7 112.9 24.6 34.4 73.5 71.0 10.9 64.5 95.8 53.5 31.1 56.1 68.8 14.0 35.6 49.0 53.7 40.6 70.9 114.2 28.3 85.8 66.4 17.1 17.5 17.2 19.1 16.5 17.6 18.7 18.2 19.4 19.3 17.8 23.0 18.7 25.6 22.4 7.5 25.5 14.5 23.6 56.9 14.2 6.7 22.7 18.5 10.6 28.6 31.0 36.8 4.2 60.0 23.5 17.3 3.9 67.1 0.5 24.1 15.1 21.4 16.4 5.7 1.3 58.3 96.2 27.9 13.7 25.4 22.2 23.8 28.9 26.4 226.7 5.0 1.7 15.0 83.4 87.5 6.8 2.5 32.0 55.5 46.2 2.8 28.4 32.2 33.0 3.0 1.7 39.5 125.0 33.4 36.6 15.1 10.8 6.8 29.9 3.3 13.1 16.5 16.9 0.6 4.8 12.4 12.4 48.0 23.9 23.0 26.2 18.5 DOCK7 "KIAA1771, ZIR2" ENSG00000116641 "Dedicator of cytokinesis 7" Q96N67 1 62454298-62688386 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 347.0;Inhibitory neurons: 103.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (2.07e-1)" "unprognostic (1.35e-2)" "unprognostic (2.69e-2)" "unprognostic (1.44e-1)" "unprognostic (4.51e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (4.90e-2)" "unprognostic (6.34e-2)" "unprognostic (1.10e-2)" "unprognostic (3.74e-3)" "unprognostic (1.18e-1)" "unprognostic (8.16e-2)" "unprognostic (4.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.62e-1)" "unprognostic (3.99e-2)" 9.9 5.9 11.3 6.6 13.6 3.1 12.4 9.6 11.6 10.7 7.2 9.9 7.0 10.7 7.7 6.5 9.4 8.3 5.9 10.3 13.6 8.9 8.0 6.4 4.3 11.3 11.9 15.4 5.8 13.9 10.9 9.9 12.4 10.2 11.3 12.6 9.8 7.9 3.6 9.8 6.7 10.4 12.9 6.1 10.6 16.4 11.4 7.3 6.3 3.7 4.8 9.0 8.0 15.2 30.8 12.3 48.8 10.9 45.8 49.6 22.6 41.9 37.5 35.6 33.5 13.4 9.6 13.3 9.4 56.6 42.4 16.2 23.7 34.4 57.9 15.9 18.2 24.1 11.8 25.0 20.8 11.1 8.7 30.0 15.8 43.5 38.4 42.8 17.8 12.7 11.7 5.0 43.2 9.2 8.7 0.8 26.3 6.6 14.3 10.6 53.1 3.7 28.9 26.4 15.3 49.2 23.5 24.6 51.9 42.9 7.8 8.5 31.7 37.6 21.4 37.3 31.5 9.3 12.7 7.2 32.1 2.7 40.0 0.0 0.4 0.0 0.2 0.7 0.6 0.5 0.1 0.4 1.4 0.2 0.1 0.4 0.0 0.1 0.2 0.3 0.1 0.2 11.3 13.6 9.6 11.6 10.3 13.6 11.3 11.9 12.4 12.9 11.4 15.2 5.3 9.6 10.1 347.0 9.1 11.9 18.3 11.1 20.5 15.4 16.3 18.4 12.2 10.0 9.6 23.9 22.9 11.8 3.8 10.1 1.9 19.9 2.2 16.9 29.6 6.1 13.1 7.6 84.8 16.0 17.1 19.5 22.4 24.1 5.7 29.2 6.1 16.6 15.3 20.2 103.9 11.5 14.2 8.7 9.5 4.5 23.0 13.1 12.4 61.8 7.0 23.8 3.1 53.8 25.9 26.5 14.5 23.0 5.7 18.3 9.4 9.7 12.4 18.5 6.6 15.8 23.4 48.8 43.9 12.6 7.7 11.6 4.7 15.7 15.6 13.8 DSTYK "DustyPK, KIAA0472, RIP5, RIPK5, SPG23" ENSG00000133059 "Dual serine/threonine and tyrosine protein kinase" Q6XUX3 1 205142505-205211702 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 89.2;Melanocytes: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044140 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "HPA044140: AB_10965031" "unprognostic (1.42e-2)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (1.02e-3)" "unprognostic (1.39e-1)" "unprognostic (2.66e-1)" "unprognostic (1.43e-2)" "unprognostic (9.01e-2)" "unprognostic (1.81e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (3.26e-2)" "unprognostic (7.80e-2)" "unprognostic (1.93e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (8.73e-5)" 4.5 7.2 11.5 3.8 11.1 19.2 6.7 11.5 12.1 6.4 6.8 6.0 2.7 7.9 5.8 5.5 7.2 4.5 4.9 11.8 11.3 7.5 2.2 6.1 4.0 13.5 10.7 11.1 4.5 13.1 5.5 6.0 13.7 5.6 3.6 13.5 4.4 6.9 9.6 12.0 4.1 7.1 9.9 6.2 4.2 5.1 11.5 6.2 6.8 6.8 4.5 5.2 5.4 13.5 9.9 6.3 6.6 8.1 9.5 15.9 4.7 12.0 12.1 12.4 8.4 2.9 5.3 7.3 3.5 20.6 6.9 6.9 7.3 7.8 12.4 3.5 7.8 13.3 8.1 3.1 8.5 3.7 6.8 9.4 11.6 12.7 12.0 14.7 9.2 5.2 17.4 4.8 10.0 6.8 2.9 3.3 7.2 1.8 7.4 2.6 12.1 6.5 8.4 6.1 3.7 7.2 10.3 10.5 34.5 7.7 7.8 4.9 9.2 7.7 7.7 11.8 8.2 4.8 3.7 4.1 9.0 5.1 28.2 8.1 1.9 3.6 2.4 1.5 2.3 1.5 1.8 2.0 1.7 1.7 2.6 1.9 2.7 2.8 1.0 1.2 1.1 1.0 11.5 11.1 11.5 12.1 11.8 11.3 13.5 10.7 13.7 9.9 11.5 13.5 15.8 28.9 15.5 26.4 15.3 14.9 7.2 10.5 14.2 48.0 14.5 13.6 13.6 12.8 15.1 16.5 33.3 6.8 15.1 3.8 5.9 12.5 11.3 16.3 37.7 16.1 12.7 31.6 35.1 9.1 6.1 19.4 8.2 11.6 24.1 43.2 28.5 6.9 8.8 89.2 36.6 6.2 6.1 23.6 15.6 25.2 16.4 11.4 90.7 21.5 20.6 45.1 23.7 17.1 43.0 10.6 5.0 18.0 11.1 10.7 6.1 6.9 24.7 37.3 26.3 22.4 16.4 22.3 13.0 10.1 13.9 2.6 15.1 27.8 7.5 6.7 E2F6 E2F-6 ENSG00000169016 "E2F transcription factor 6" O75461 2 11444375-11466177 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "basophil: 7.8" "Lineage enriched" "Detected in single" 17 "granulocytes: 7.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA075185 Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA075185: AB_2732282" "unprognostic (7.13e-2)" "unprognostic (2.44e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.13e-4)" "unprognostic (4.18e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.90e-1)" "unprognostic (3.05e-3)" "unprognostic (7.58e-2)" "unprognostic (3.17e-3)" "unprognostic (3.64e-3)" "unprognostic (2.08e-3)" "unprognostic (2.72e-2)" "unprognostic (1.02e-1)" "unprognostic (9.01e-2)" "unprognostic (2.13e-1)" 5.5 5.2 5.0 2.5 5.3 3.8 4.3 5.1 6.2 3.3 5.1 4.5 2.8 5.4 3.9 2.7 4.9 3.1 7.6 4.8 5.8 2.6 2.8 3.0 2.4 5.3 5.4 4.7 4.6 3.4 5.0 3.1 5.1 3.3 2.2 3.5 3.6 3.4 14.6 3.7 3.6 4.4 5.1 3.2 4.9 2.8 5.2 2.5 2.7 11.5 1.9 4.0 3.0 5.2 4.2 5.2 10.7 6.0 4.8 3.9 8.0 4.0 7.1 4.6 4.2 10.3 5.6 8.2 4.5 4.6 9.3 3.1 7.6 5.9 4.8 10.6 11.3 14.9 4.0 12.8 9.4 15.4 14.7 6.7 5.5 5.0 5.9 3.9 4.2 7.1 11.3 15.3 3.7 10.1 8.9 16.9 15.3 5.1 6.7 15.6 12.1 8.4 5.0 3.7 9.2 19.1 4.6 6.7 18.8 4.6 6.2 7.7 3.5 6.6 8.5 4.2 9.0 22.0 17.4 19.9 7.2 14.5 10.3 7.8 0.2 0.1 0.1 0.0 0.4 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 5.0 5.3 5.1 6.2 4.8 5.8 5.3 5.4 5.1 5.1 5.2 5.2 15.7 6.4 4.8 7.2 8.4 24.3 23.6 10.6 13.6 12.4 14.5 9.7 9.0 10.0 8.4 3.7 16.7 17.3 8.5 3.4 7.9 11.7 1.4 11.0 14.1 12.2 6.7 3.4 13.9 11.0 13.9 14.3 13.3 14.0 0.0 13.6 8.6 8.8 12.5 13.5 14.9 4.7 8.2 5.4 11.5 2.6 8.7 11.3 17.8 6.5 7.0 10.1 5.2 3.5 20.8 9.4 3.7 11.3 6.1 21.3 5.3 8.4 4.1 11.8 0.0 22.2 12.3 15.7 48.2 8.2 21.9 22.2 8.4 11.7 6.0 16.7 EGFL8 "C6orf8, NG3" ENSG00000241404 "EGF like domain multiple 8" Q99944 6 32164595-32168281 "Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 6.4;Granulosa cells: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 3.2;SK-MEL-30: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061173 Uncertain Approved "Nuclear speckles,Vesicles" "Secreted - unknown location" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nuclear speckles" "HPA061173: AB_2684443" "unprognostic (7.13e-2)" "unprognostic (1.86e-1)" "unprognostic (6.79e-3)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (7.60e-4)" "unprognostic (3.42e-2)" "unprognostic (2.49e-1)" "unprognostic (6.42e-3)" "unprognostic (1.97e-1)" "unprognostic (7.60e-3)" "unprognostic (8.11e-3)" "unprognostic (1.07e-4)" "unprognostic (1.11e-1)" "unprognostic (6.79e-2)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" 13.3 7.2 3.8 0.5 3.5 1.1 13.6 3.6 5.7 23.4 4.1 19.8 0.6 10.0 0.8 12.3 16.3 3.0 14.2 3.9 3.9 16.3 7.4 9.4 0.3 3.8 3.9 31.2 5.1 0.4 8.2 2.9 3.7 16.9 0.5 0.0 7.9 1.4 3.8 12.8 8.8 0.3 3.8 7.9 10.2 4.4 4.1 0.6 8.7 2.5 0.2 13.5 17.2 3.8 0.2 0.1 0.4 1.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.5 0.0 0.3 3.2 0.0 0.0 0.3 0.0 0.4 0.2 0.1 0.0 0.2 0.7 0.5 0.0 0.0 0.6 1.0 1.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 3.4 0.0 1.0 0.7 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 3.5 3.6 5.7 3.9 3.9 3.8 3.9 3.7 3.8 4.1 3.8 1.2 6.4 4.1 0.0 0.3 1.5 0.6 0.3 4.6 1.5 0.5 0.3 0.1 0.0 1.6 1.8 2.1 0.8 0.6 0.2 0.0 0.4 0.1 1.0 1.9 1.7 0.0 1.7 0.0 0.2 0.4 1.5 4.6 1.3 0.0 10.4 3.3 0.3 0.2 0.0 0.0 1.1 0.0 0.6 1.6 0.2 3.7 0.7 0.0 0.0 0.0 0.9 3.1 0.0 0.0 0.3 0.2 1.2 2.1 0.7 0.4 0.1 1.6 1.5 0.0 2.0 1.5 0.5 0.4 4.0 2.3 0.8 0.9 1.5 1.3 0.5 EIF1B GC20 ENSG00000114784 "Eukaryotic translation initiation factor 1B" O60739 3 40309707-40312424 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 362.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.54e-1)" "unprognostic (1.06e-2)" "unprognostic (1.31e-2)" "unprognostic (3.20e-3)" "unprognostic (7.64e-2)" "unprognostic (7.91e-2)" "prognostic unfavorable (1.94e-5)" "unprognostic (3.16e-2)" "unprognostic (9.87e-2)" "unprognostic (3.02e-2)" "unprognostic (1.13e-2)" "unprognostic (2.17e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.33e-1)" "unprognostic (1.23e-1)" "unprognostic (1.82e-1)" "unprognostic (8.87e-2)" 81.6 92.0 88.1 47.8 90.5 221.8 66.7 97.3 134.4 64.2 76.7 78.2 41.2 66.8 59.9 41.9 75.1 61.3 362.7 90.7 123.2 118.4 92.4 73.9 67.7 110.8 98.4 103.3 60.3 77.2 91.0 53.0 106.6 52.3 42.2 94.5 47.9 56.5 157.4 47.7 55.5 59.1 93.3 62.6 70.9 83.3 92.3 62.7 59.2 146.5 59.8 89.9 53.7 99.7 41.1 33.1 110.0 62.9 130.2 127.0 65.6 82.1 107.6 79.8 103.0 52.1 54.1 83.7 44.5 56.4 47.8 27.3 75.9 40.4 80.8 127.6 76.9 135.5 33.4 120.4 206.3 82.4 66.8 93.0 121.8 70.2 119.2 112.5 85.2 55.9 115.5 100.5 93.2 26.1 66.7 89.2 149.5 36.3 87.0 45.4 61.4 68.1 78.3 51.6 46.7 76.5 59.4 34.1 238.6 103.4 43.6 82.8 65.8 45.8 47.3 93.6 58.5 92.5 177.2 121.4 57.3 89.7 66.6 93.0 48.5 138.1 36.4 57.8 43.6 95.1 44.4 47.0 45.3 83.8 51.8 45.8 133.2 40.9 55.7 73.2 58.4 41.0 88.1 90.5 97.3 134.4 90.7 123.2 110.8 98.4 106.6 93.3 92.3 99.7 178.9 93.0 63.1 15.7 216.5 190.0 226.5 133.8 227.1 108.6 94.7 119.0 454.8 81.5 83.3 88.3 54.2 113.9 125.0 114.3 293.5 97.2 167.3 139.6 146.0 115.5 117.5 294.1 45.2 114.6 120.2 207.4 69.8 141.5 130.0 104.3 102.1 75.1 128.5 149.7 50.9 82.1 99.7 172.0 135.4 71.5 109.0 192.1 149.4 20.6 138.0 157.5 118.4 23.1 33.4 85.0 183.6 91.7 76.9 119.8 138.7 292.1 81.5 189.8 92.1 161.7 187.6 493.0 268.2 137.8 147.8 115.6 143.4 80.9 88.7 206.7 EIF4EBP1 "4E-BP1, PHAS-I" ENSG00000187840 "Eukaryotic translation initiation factor 4E binding protein 1" Q13541 8 38030534-38060365 "Cancer-related genes, Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 188.9;salivary gland: 164.2" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 730.0;Pancreatic endocrine cells: 277.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005032, CAB005039, HPA023501" Supported Supported Nucleoplasm,Cytosol NA NA 44000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "CAB005032: AB_562030, CAB005039: AB_562029, HPA023501: AB_1848095" "unprognostic (1.55e-2)" "unprognostic (2.45e-1)" "unprognostic (1.58e-1)" "prognostic unfavorable (8.86e-4)" "unprognostic (6.94e-2)" "unprognostic (2.69e-1)" "unprognostic (1.94e-2)" "unprognostic (3.27e-2)" "unprognostic (1.61e-1)" "unprognostic (1.16e-2)" "unprognostic (3.18e-3)" "unprognostic (7.21e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.98e-2)" "unprognostic (3.01e-1)" "unprognostic (4.57e-2)" "unprognostic (5.72e-3)" 60.9 12.6 7.7 16.9 8.0 35.0 53.6 8.0 10.9 24.9 12.7 25.3 18.5 19.7 2.2 86.0 21.7 8.9 32.7 8.0 9.8 19.5 63.5 25.0 10.3 9.8 8.5 22.2 188.9 7.8 9.2 28.6 9.8 19.2 15.4 1.5 164.2 17.0 98.1 20.8 23.1 14.4 8.5 23.9 43.8 5.5 10.1 9.6 9.6 27.2 10.4 33.6 26.5 10.8 146.9 113.2 32.4 193.2 41.3 32.3 77.0 130.5 111.9 128.4 203.5 74.8 56.3 46.3 101.5 121.3 77.1 85.1 109.1 197.5 74.8 36.0 190.9 269.6 52.0 104.9 423.6 98.8 60.4 100.0 314.9 142.0 264.1 40.1 208.2 57.7 152.7 221.8 54.8 141.7 95.9 297.8 186.0 112.9 243.7 80.3 80.4 197.4 49.3 22.3 281.6 200.8 26.1 78.8 534.8 20.3 105.8 192.2 105.2 76.1 167.1 179.9 137.8 185.1 121.6 72.1 173.4 213.4 169.1 51.1 416.3 258.3 27.9 336.6 27.3 130.7 32.8 30.9 335.0 103.3 26.2 26.0 39.4 35.0 268.3 242.6 66.0 258.3 7.7 8.0 8.0 10.9 8.0 9.8 9.8 8.5 9.8 8.5 10.1 10.8 23.6 9.6 8.3 1.6 25.2 74.4 42.4 114.8 51.8 3.6 84.8 72.8 41.7 57.2 97.3 20.2 2.1 41.3 27.3 70.1 29.4 226.1 17.0 11.6 39.0 54.6 40.2 79.9 0.8 730.0 224.2 68.6 35.7 12.5 18.4 76.0 65.3 103.4 223.4 0.0 1.3 138.2 79.3 108.6 82.2 106.2 43.5 83.9 72.9 1.9 101.9 19.2 21.6 4.0 0.4 277.9 64.5 19.2 38.7 100.2 19.5 103.1 33.5 2.2 13.1 17.6 85.2 1.9 25.5 209.3 85.4 38.6 19.8 69.3 83.8 58.9 ENTHD1 FLJ25421 ENSG00000176177 "ENTH domain containing 1" Q8IYW4 22 39743044-39893864 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 11.0" "Cell type enhanced" "Detected in some" "Early spermatids: 21.2;granulocytes: 8.9;Late spermatids: 17.5;Spermatocytes: 37.4;Spermatogonia: 6.7" "Cancer enriched" "Detected in single" 30 "melanoma: 7.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SK-MEL-30: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA019800 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA019800: AB_1848842" "unprognostic (5.28e-3)" "unprognostic (1.27e-1)" "unprognostic (8.04e-2)" "unprognostic (9.84e-3)" "unprognostic (2.97e-4)" "unprognostic (6.02e-2)" "unprognostic (1.16e-1)" "unprognostic (2.17e-1)" "unprognostic (7.32e-2)" "unprognostic (1.47e-4)" "unprognostic (3.60e-2)" "unprognostic (7.75e-10)" "unprognostic (3.68e-2)" "unprognostic (8.56e-2)" "unprognostic (4.99e-2)" "unprognostic (1.06e-1)" 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 11.0 0.0 1.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 8.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 17.5 0.6 1.1 0.0 0.0 0.7 0.0 0.0 1.5 0.2 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 37.4 6.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 ENTPD6 "CD39L2, dJ738P15.3, IL6ST2, NTPDase-6" ENSG00000197586 "Ectonucleoside triphosphate diphosphohydrolase 6" O75354 20 25195693-25228075 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 289.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015491, HPA069555" Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 41000 "Cluster 39: Non-specific - mRNA processing" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA015491: AB_2669200, HPA069555: AB_2686152" "unprognostic (3.24e-1)" "unprognostic (1.27e-2)" "unprognostic (5.91e-2)" "unprognostic (1.16e-1)" "unprognostic (1.76e-1)" "unprognostic (4.44e-1)" "unprognostic (2.10e-3)" "unprognostic (7.41e-3)" "unprognostic (2.74e-3)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (1.03e-1)" "unprognostic (8.14e-3)" "unprognostic (1.78e-2)" "unprognostic (2.74e-1)" "unprognostic (4.86e-2)" "unprognostic (4.48e-2)" 24.8 55.4 54.3 22.8 64.0 15.2 27.7 39.7 65.9 22.9 26.5 61.0 60.0 21.8 18.4 25.3 23.2 26.5 75.9 56.0 49.8 40.4 38.9 25.4 16.1 29.6 32.2 36.2 49.6 23.5 60.0 25.2 45.2 55.7 44.9 15.7 71.2 17.2 38.7 19.4 63.0 18.6 25.7 19.8 47.2 36.3 48.5 29.8 28.8 21.9 13.0 24.5 21.8 38.9 78.8 122.8 32.9 64.0 41.0 50.8 70.8 63.0 45.0 54.0 48.3 65.5 60.0 47.6 91.4 60.9 104.7 100.3 40.1 96.2 35.5 29.2 36.2 38.3 18.2 150.4 60.7 52.7 57.3 47.4 53.1 67.7 51.4 39.4 43.7 46.1 51.5 78.8 40.0 75.6 49.2 32.6 20.8 63.9 96.0 27.1 102.9 108.4 67.8 46.3 52.0 26.7 17.7 105.1 289.4 29.6 75.3 43.4 48.6 61.9 63.7 51.6 75.7 50.5 43.8 21.0 44.5 34.1 116.3 0.1 25.2 4.9 18.8 17.0 25.6 8.7 16.5 15.0 26.4 11.0 16.9 15.5 1.1 14.1 7.6 18.5 17.2 22.1 54.3 64.0 39.7 65.9 56.0 49.8 29.6 32.2 45.2 25.7 48.5 38.9 6.4 19.2 28.5 12.4 9.9 9.8 16.2 23.6 6.2 19.2 25.8 21.8 5.8 25.8 14.8 18.4 10.4 63.2 11.0 81.4 9.8 42.5 22.1 10.5 7.6 7.6 34.0 4.2 18.6 40.1 21.7 12.8 52.5 15.4 3.8 65.2 14.3 15.0 26.7 25.2 19.4 57.5 26.4 17.7 17.4 65.2 20.5 17.6 10.6 11.2 16.0 4.2 10.3 13.0 9.2 33.8 59.8 42.2 16.5 27.9 68.4 13.5 10.7 9.1 6.6 6.3 9.6 3.0 8.8 8.6 6.0 59.8 12.0 25.8 72.6 12.1 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ETFRF1 LYRM5 ENSG00000205707 "Electron transfer flavoprotein regulatory factor 1" Q6IPR1 12 25195216-25209645 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 305.2;Proximal tubular cells: 183.8;Theca cells: 69.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044255 Approved NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "HPA044255: AB_10967895" "prognostic favorable (9.63e-4)" "unprognostic (1.30e-1)" "unprognostic (2.01e-1)" "unprognostic (9.17e-2)" "unprognostic (5.96e-2)" "unprognostic (1.70e-1)" "unprognostic (3.57e-3)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (2.49e-2)" "unprognostic (3.41e-2)" "prognostic favorable (9.23e-5)" "unprognostic (1.55e-1)" "unprognostic (4.04e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-3)" 28.2 46.3 43.9 13.5 48.3 12.9 35.0 49.5 69.8 25.7 41.2 17.9 33.4 19.6 35.6 22.5 18.3 22.5 53.1 43.4 47.4 55.9 121.3 21.7 17.9 50.0 46.4 20.6 24.1 37.2 15.1 17.5 49.5 26.4 19.4 30.4 30.4 20.6 89.1 24.2 23.9 18.3 49.7 18.3 30.3 56.3 45.8 18.9 43.2 101.5 16.5 18.1 12.0 57.0 13.4 12.6 16.8 11.1 25.4 40.4 12.1 14.7 21.4 15.1 17.4 6.0 15.0 4.3 10.2 23.4 9.6 9.4 14.2 14.9 17.0 15.9 12.1 21.5 13.8 7.9 27.3 19.4 12.1 26.1 48.9 13.8 23.5 46.5 23.9 23.9 25.5 13.5 24.1 14.1 16.9 50.1 26.8 29.6 16.1 11.2 19.8 26.2 40.8 10.4 17.3 12.2 13.4 14.1 40.2 42.5 21.7 27.1 14.0 6.0 8.1 33.1 9.2 16.6 10.9 16.6 26.2 15.2 18.7 24.9 8.5 7.8 8.5 9.5 12.1 21.3 15.2 11.6 8.9 16.8 27.7 22.6 15.6 17.1 6.2 13.3 7.7 12.3 43.9 48.3 49.5 69.8 43.4 47.4 50.0 46.4 49.5 49.7 45.8 57.0 38.0 19.2 24.4 0.0 10.6 0.0 0.0 0.0 0.0 0.0 39.1 48.8 0.0 0.0 9.3 27.6 0.0 56.2 11.9 0.0 305.2 31.0 0.0 36.8 17.0 13.8 0.0 0.0 0.0 45.8 19.2 12.1 0.0 36.1 11.4 14.2 0.0 0.0 38.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 25.6 0.0 0.0 3.0 0.0 0.0 183.8 4.4 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 65.5 9.0 69.1 0.0 0.0 ETV4 "E1A-F, E1AF, PEA3" ENSG00000175832 "ETS variant transcription factor 4" P43268 17 43527844-43579620 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 23.3;Cholangiocytes: 17.2;Distal tubular cells: 17.6;Enteroendocrine cells: 14.9;Extravillous trophoblasts: 19.8;Syncytiotrophoblasts: 14.9" "Cancer enhanced" "Detected in all" "testis cancer: 80.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 177.7;Hep G2: 173.0;SK-MEL-30: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005768 Approved Supported "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli rim" "Mitotic chromosome" "HPA005768: AB_1848294" "unprognostic (2.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.14e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-2)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.58e-2)" "unprognostic (5.34e-2)" "unprognostic (8.13e-2)" "unprognostic (7.05e-2)" "unprognostic (3.01e-1)" "unprognostic (7.79e-2)" "unprognostic (2.03e-1)" "unprognostic (7.08e-2)" "prognostic favorable (7.60e-4)" "unprognostic (1.69e-1)" 0.5 2.4 1.2 1.0 1.6 0.0 7.0 0.8 2.2 3.6 0.0 2.0 6.1 2.4 1.0 9.2 2.5 6.4 3.1 1.3 0.8 5.4 1.2 2.2 0.6 1.0 0.9 0.4 7.8 7.9 14.7 5.2 1.4 4.5 1.7 3.0 4.6 3.6 1.3 6.4 4.2 1.4 0.3 0.4 3.8 1.2 0.7 0.3 6.9 2.5 4.8 2.1 5.3 0.9 24.5 67.0 80.4 177.7 3.1 20.1 17.9 7.9 21.1 14.9 15.2 38.1 33.9 0.1 4.3 4.1 36.6 43.6 2.7 40.2 13.2 0.8 0.5 2.3 10.7 173.0 4.3 47.0 20.9 3.6 1.4 56.8 35.0 16.8 32.1 0.3 48.9 0.1 31.0 9.8 0.2 82.9 116.9 123.1 110.9 99.8 9.8 58.9 33.0 17.3 0.1 71.4 2.1 4.5 197.0 43.8 0.8 13.9 15.1 10.6 52.0 15.7 22.1 7.3 47.8 0.1 18.9 8.9 63.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.8 2.2 1.3 0.8 1.0 0.9 1.4 0.3 0.7 0.9 0.2 0.0 0.0 1.3 0.0 1.9 2.5 3.6 23.3 3.2 10.4 12.3 1.1 17.2 2.4 0.0 0.0 2.3 0.1 1.1 17.6 6.5 3.1 0.7 0.3 1.5 14.9 0.0 1.6 1.0 19.8 1.9 3.1 1.6 0.0 0.2 0.7 0.0 0.8 0.0 1.0 4.0 2.0 0.3 0.3 6.0 0.3 0.2 3.6 1.0 0.0 10.9 0.0 1.0 0.0 3.7 3.3 0.4 0.0 0.9 1.9 0.1 1.0 0.3 0.0 2.1 1.7 0.0 1.3 3.6 1.1 14.9 0.3 0.1 7.7 4.3 ETV5 ERM ENSG00000244405 "ETS variant transcription factor 5" P41161 3 186046314-186110318 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 94.0;Oligodendrocyte precursor cells: 169.9;Syncytiotrophoblasts: 88.8" "Cancer enhanced" "Detected in all" "melanoma: 50.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 178.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009590, HPA063065, HPA073889" Approved Enhanced Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB009590: AB_2101008, HPA063065: AB_2684936, HPA073889: " "unprognostic (3.85e-1)" "unprognostic (5.81e-2)" "unprognostic (1.54e-2)" "unprognostic (3.30e-1)" "unprognostic (9.00e-2)" "unprognostic (2.56e-3)" "prognostic unfavorable (7.85e-9)" "unprognostic (3.52e-3)" "unprognostic (2.97e-1)" "unprognostic (1.22e-2)" "unprognostic (4.18e-2)" "unprognostic (1.48e-1)" "unprognostic (1.57e-3)" "unprognostic (6.80e-2)" "unprognostic (1.57e-1)" "unprognostic (3.58e-2)" "unprognostic (3.84e-3)" 6.8 39.3 17.1 6.9 22.4 1.4 15.0 17.7 24.4 4.9 9.4 3.4 6.1 8.1 7.3 4.2 5.1 5.6 11.5 17.8 16.8 8.9 7.9 29.6 5.2 20.5 17.1 2.2 17.5 42.2 25.4 17.1 17.7 7.4 3.2 15.9 6.5 5.8 11.9 6.4 3.0 7.4 14.7 10.9 14.8 9.3 17.2 4.8 21.9 7.0 4.2 4.3 4.1 19.6 42.4 28.6 36.1 79.2 21.9 22.7 2.6 35.7 39.7 27.7 29.6 31.7 25.4 1.1 46.4 34.7 41.3 7.1 0.8 27.2 40.7 9.3 1.0 12.4 1.0 36.4 36.3 31.2 22.1 19.9 4.4 44.3 53.7 32.9 41.0 4.4 11.6 14.6 47.5 19.8 4.1 47.7 54.2 12.1 32.4 86.6 36.0 28.7 23.0 9.9 1.6 45.8 8.7 0.4 178.3 14.4 0.1 17.3 40.0 15.0 24.3 38.2 70.5 11.1 49.9 0.3 45.8 24.6 91.6 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.0 0.1 17.1 22.4 17.7 24.4 17.8 16.8 20.5 17.1 17.7 14.7 17.2 19.6 5.7 3.2 68.5 26.1 5.6 15.7 10.6 8.2 45.5 17.8 9.4 30.4 5.7 17.2 2.4 0.0 12.5 57.6 3.1 0.6 3.9 9.4 24.6 2.0 4.3 9.2 10.7 1.7 94.0 9.4 18.8 12.5 15.8 4.7 8.2 0.8 10.4 9.0 56.4 5.0 43.7 2.8 0.0 64.4 19.4 49.0 9.0 27.1 16.0 45.9 2.1 60.4 1.0 169.9 47.5 12.5 1.1 15.4 4.9 3.6 1.5 22.9 1.3 18.8 0.0 25.4 13.6 16.9 14.4 8.7 5.3 88.8 1.9 3.1 1.5 2.7 FAM167B "C1orf90, DIORA-2, MGC10820" ENSG00000183615 "Family with sequence similarity 167 member B" Q9BTA0 1 32247222-32248856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 44.0" "Group enriched" "Detected in many" 14 "Adipocytes: 68.5;Endothelial cells: 102.5;Hepatic stellate cells: 200.3" "Cancer enhanced" "Detected in all" "melanoma: 46.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Lineage enriched" "Detected in single" 5 "T-cells: 1.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 9.6;EFO-21: 12.0;SK-MEL-30: 30.9;U-2197: 29.9" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA029398, HPA062074" Uncertain Approved "Actin filaments" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "HPA029398: AB_10602807, HPA062074: AB_2684677" "unprognostic (2.16e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.03e-2)" "unprognostic (1.74e-2)" "unprognostic (3.36e-3)" "unprognostic (7.44e-3)" "unprognostic (3.64e-1)" "unprognostic (3.00e-3)" "unprognostic (1.02e-2)" "unprognostic (1.30e-2)" "unprognostic (8.89e-2)" "unprognostic (4.80e-2)" "unprognostic (2.69e-2)" "unprognostic (1.60e-1)" "unprognostic (8.04e-2)" "unprognostic (5.08e-2)" 19.9 19.7 4.3 4.1 3.8 0.2 10.0 3.8 6.3 14.3 4.3 7.4 2.8 12.9 0.5 4.0 10.3 4.2 11.0 3.8 4.5 44.0 10.7 20.5 2.7 4.5 4.1 4.1 8.4 4.3 14.4 4.2 4.5 16.5 2.1 1.4 4.7 5.9 3.0 2.4 8.1 5.8 4.4 1.9 7.5 0.9 5.1 0.8 19.9 1.1 1.5 13.2 7.7 4.3 0.9 1.8 0.6 0.0 1.2 1.1 0.0 4.3 9.6 1.9 2.7 0.1 0.9 0.2 12.0 7.3 2.2 1.4 0.3 0.0 0.6 0.1 0.0 0.0 4.6 0.5 0.4 0.0 0.1 1.0 0.7 1.4 0.4 2.6 3.5 0.6 0.0 0.1 0.2 0.6 0.2 0.0 0.3 0.2 4.1 0.9 0.0 1.2 1.2 0.4 1.8 0.4 2.8 0.2 30.9 0.8 0.5 0.1 3.2 0.8 0.9 29.9 0.1 0.1 0.3 0.7 0.3 0.2 0.4 0.0 0.0 0.2 0.8 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.1 0.5 0.0 0.1 0.0 0.0 1.7 0.2 4.3 3.8 3.8 6.3 3.8 4.5 4.5 4.1 4.5 4.4 5.1 4.3 68.5 0.0 1.1 0.3 3.2 0.3 0.5 0.2 0.0 0.4 2.8 2.8 0.4 0.0 0.1 5.5 0.0 0.1 2.7 1.3 0.0 0.5 0.0 1.3 3.5 102.5 0.0 8.0 0.0 0.8 0.2 3.7 1.5 1.0 0.0 0.2 200.3 1.7 0.6 0.0 0.1 1.3 0.0 8.5 2.2 0.0 2.8 1.4 1.8 2.8 0.0 0.0 2.1 0.5 0.4 0.2 1.2 1.2 0.6 0.6 0.0 0.1 1.3 0.5 0.0 0.6 1.6 0.0 0.3 0.3 1.0 0.3 2.1 0.9 0.7 0.3 FAM210B "C20orf108, dJ1167H4.1, DKFZP434A1114" ENSG00000124098 "Family with sequence similarity 210 member B" Q96KR6 20 56358974-56368663 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 449.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 299.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042652 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA042652: AB_2678098" "unprognostic (3.29e-1)" "prognostic favorable (5.44e-4)" "unprognostic (3.24e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-1)" "unprognostic (3.34e-2)" "unprognostic (9.45e-2)" "prognostic favorable (4.26e-4)" "unprognostic (1.77e-1)" "unprognostic (2.24e-2)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" "prognostic favorable (1.44e-10)" "unprognostic (1.08e-1)" "unprognostic (3.27e-2)" "unprognostic (1.84e-1)" "unprognostic (3.00e-1)" 38.2 87.6 32.1 13.9 34.1 85.2 62.0 30.0 33.6 43.7 37.7 39.8 24.7 36.5 45.7 31.1 40.1 40.6 43.9 33.9 32.6 34.6 100.3 28.2 13.9 29.6 33.8 108.9 41.5 32.7 28.1 36.7 29.9 66.8 30.6 30.0 54.9 58.7 75.2 36.5 23.3 34.2 29.6 19.6 34.2 14.1 35.9 20.6 28.4 102.2 20.0 32.5 32.7 29.1 19.9 7.5 29.3 71.6 83.2 93.4 57.1 23.8 53.4 42.6 48.7 13.9 9.6 1.6 12.1 40.9 24.6 56.2 15.9 68.7 71.0 2.9 24.9 12.2 16.9 132.0 54.4 1.3 7.4 80.2 75.2 24.1 34.0 49.3 69.4 10.2 93.6 12.7 52.7 20.6 10.4 5.4 24.9 29.0 46.7 0.1 60.4 15.9 21.9 22.9 40.4 72.9 57.9 124.6 299.1 62.3 55.0 11.1 48.4 37.8 25.2 61.0 14.7 9.9 10.9 0.4 30.0 7.7 25.2 2.3 2.3 6.9 1.7 3.3 1.3 1.1 1.9 2.3 1.7 1.3 2.0 1.9 1.0 1.4 1.5 1.5 2.3 1.0 32.1 34.1 30.0 33.6 33.9 32.6 29.6 33.8 29.9 29.6 35.9 29.1 30.3 16.0 29.3 4.2 7.4 24.9 85.4 28.2 70.6 10.3 57.5 98.8 56.8 54.3 19.3 16.5 39.6 77.7 13.5 23.8 64.6 27.9 1.0 41.4 49.0 28.8 50.9 449.3 5.7 19.5 26.3 46.1 44.9 37.4 19.1 47.5 46.1 154.5 28.0 1.7 6.6 28.6 20.3 44.1 21.2 4.7 66.8 26.2 37.4 5.6 36.6 27.8 14.4 4.0 8.4 35.7 15.3 155.7 9.4 48.7 34.1 46.1 15.6 19.2 19.7 28.1 37.1 1.1 9.4 68.6 32.5 41.9 14.6 123.4 33.4 56.3 FAM222B "C17orf63, FLJ10700" ENSG00000173065 "Family with sequence similarity 222 member B" Q8WU58 17 28755978-28855232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 73.8;Inhibitory neurons: 84.7;Oligodendrocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051840, HPA062239" Approved Enhanced Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA051840: AB_2681633, HPA062239: AB_2684722" "unprognostic (4.11e-2)" "unprognostic (9.72e-2)" "unprognostic (9.12e-2)" "unprognostic (2.40e-3)" "unprognostic (1.57e-1)" "unprognostic (2.12e-2)" "prognostic unfavorable (3.45e-4)" "unprognostic (1.18e-2)" "unprognostic (1.05e-1)" "unprognostic (8.28e-3)" "unprognostic (1.63e-1)" "unprognostic (1.79e-1)" "unprognostic (3.70e-2)" "unprognostic (2.37e-2)" "unprognostic (1.46e-1)" "unprognostic (3.61e-2)" "unprognostic (7.18e-2)" 8.6 6.3 6.9 6.9 7.3 7.0 8.4 14.1 9.5 9.3 18.8 11.2 12.3 7.5 7.8 11.1 7.0 8.6 10.9 6.6 6.8 10.5 7.7 8.0 6.6 8.7 6.8 8.4 8.0 10.5 10.2 9.9 8.1 9.3 10.0 10.0 14.2 8.8 43.4 7.9 11.0 7.1 2.8 6.6 8.4 27.5 9.8 7.9 8.5 16.2 7.1 10.7 9.8 7.1 13.1 25.1 21.2 24.4 17.7 12.3 23.2 9.1 8.5 12.5 12.6 32.4 12.6 13.3 17.9 10.2 16.0 16.2 17.7 20.4 10.4 18.7 24.1 15.0 12.9 24.9 20.4 9.9 23.1 12.9 19.8 17.7 15.7 12.6 25.2 15.5 29.1 9.2 26.4 16.5 16.9 7.9 24.3 17.5 9.4 7.9 20.1 13.4 22.4 16.4 23.0 16.1 12.9 24.8 31.8 44.0 18.9 9.3 28.8 8.3 17.1 9.4 14.5 18.5 24.9 8.8 11.4 6.8 15.5 15.9 3.9 9.5 6.4 5.0 7.6 6.2 5.4 6.6 5.4 4.6 7.3 6.3 4.5 3.9 7.9 4.9 5.2 4.2 6.9 7.3 14.1 9.5 6.6 6.8 8.7 6.8 8.1 2.8 9.8 7.1 10.3 3.2 7.3 49.3 12.0 9.4 7.7 14.7 9.1 14.8 14.7 10.3 13.6 31.5 9.1 7.3 27.1 7.9 6.5 22.9 3.9 18.1 56.9 11.0 10.8 13.7 25.9 14.7 73.8 13.3 10.6 7.9 11.7 17.1 10.1 8.1 31.4 11.4 8.7 25.2 84.7 17.3 20.3 8.4 5.7 45.3 12.5 6.8 7.2 41.2 8.3 6.2 8.2 64.3 79.0 24.1 12.7 7.9 8.6 14.0 18.3 11.2 10.0 8.0 0.0 9.5 6.5 51.9 34.8 9.2 6.7 6.0 10.7 8.1 19.0 10.4 FAM53A DNTNP ENSG00000174137 "Family with sequence similarity 53 member A" Q6NSI3 4 1617915-1684261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 12.8" "Cell type enhanced" "Detected in some" "Early spermatids: 12.8;Oligodendrocytes: 14.8;Spermatocytes: 14.6;Spermatogonia: 11.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "PC-3: 3.8;SCLC-21H: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036452, HPA058138" Enhanced Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA036452: AB_10671841, HPA058138: AB_2683619" "unprognostic (8.78e-2)" "unprognostic (1.16e-2)" "unprognostic (2.92e-1)" "unprognostic (2.52e-1)" "unprognostic (7.59e-2)" "unprognostic (3.45e-2)" "unprognostic (5.27e-2)" "unprognostic (1.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.44e-1)" "unprognostic (5.33e-3)" "unprognostic (7.80e-2)" "unprognostic (2.14e-3)" "unprognostic (3.73e-2)" "unprognostic (1.03e-1)" "unprognostic (5.26e-3)" "unprognostic (1.15e-3)" 1.2 1.1 1.5 0.4 2.3 0.6 1.1 1.7 1.7 1.2 0.6 1.2 0.2 1.3 1.7 0.8 1.2 0.5 0.8 1.0 1.6 1.0 1.8 0.6 0.5 2.9 2.4 1.3 1.5 0.5 5.6 0.2 2.5 0.9 0.0 0.0 1.2 0.4 1.1 1.4 0.8 0.4 1.8 1.0 1.2 12.8 2.3 0.3 3.7 0.2 0.2 1.1 0.8 3.8 0.6 0.1 0.7 1.4 0.2 0.9 0.5 2.5 1.5 1.7 1.3 0.4 0.8 1.8 1.4 0.5 0.7 0.2 0.0 0.3 0.5 0.3 0.6 0.4 0.2 0.4 1.7 0.0 0.6 0.8 1.5 0.6 1.9 0.4 0.4 2.8 1.1 0.2 0.6 0.5 0.5 1.7 0.6 0.3 3.8 0.5 0.2 0.0 0.5 0.5 4.4 2.4 1.2 0.1 2.1 0.4 1.8 0.7 0.4 0.2 0.1 0.8 0.4 0.3 1.0 0.5 0.0 0.6 3.2 0.0 0.3 0.3 0.1 0.9 0.3 0.5 0.2 0.2 0.7 0.5 1.1 0.0 0.0 0.2 0.4 1.7 0.3 0.3 1.5 2.3 1.7 1.7 1.0 1.6 2.9 2.4 2.5 1.8 2.3 3.8 1.0 0.0 0.0 0.7 0.5 1.3 0.4 0.5 1.2 0.7 0.9 0.5 3.6 1.5 0.2 1.8 0.0 0.1 0.1 0.4 1.9 0.6 12.8 0.3 0.7 0.7 0.0 1.3 2.0 1.0 0.0 0.8 1.1 0.8 0.0 0.9 1.1 0.7 0.2 0.0 1.9 0.1 0.0 0.6 0.7 2.0 0.6 0.6 0.0 1.0 0.6 0.2 0.0 2.5 14.8 0.5 0.1 0.4 0.2 0.4 0.0 0.5 0.3 0.4 0.0 1.3 1.9 14.6 11.0 1.6 0.4 0.0 0.7 1.2 0.4 0.2 FAM53B "bA12J10.2, KIAA0140, smp" ENSG00000189319 "Family with sequence similarity 53 member B" Q14153 10 124619292-124744378 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037751, HPA037752" Approved Approved Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA037751: AB_2675645, HPA037752: AB_10672285" "unprognostic (7.88e-2)" "prognostic favorable (4.96e-4)" "unprognostic (1.73e-2)" "unprognostic (2.92e-1)" "unprognostic (4.91e-1)" "prognostic favorable (1.97e-4)" "unprognostic (2.52e-2)" "unprognostic (5.03e-3)" "unprognostic (1.51e-2)" "unprognostic (4.02e-2)" "prognostic favorable (7.00e-6)" "unprognostic (1.93e-1)" "prognostic favorable (4.81e-7)" "prognostic favorable (3.26e-4)" "unprognostic (3.41e-1)" "unprognostic (2.03e-1)" "unprognostic (2.45e-2)" 12.6 19.2 21.6 14.3 33.3 25.8 8.3 18.1 30.5 12.8 8.4 12.4 15.4 23.6 3.9 13.2 11.2 5.7 18.9 21.1 16.5 10.6 4.2 10.7 31.0 30.3 25.6 19.1 7.2 12.4 12.7 4.9 22.7 8.9 7.1 6.3 15.2 7.0 55.0 14.4 17.1 12.8 17.3 20.1 9.6 15.6 35.9 32.9 16.2 22.3 21.7 8.6 8.0 51.7 10.7 12.5 9.6 27.5 11.3 5.8 26.2 4.8 6.7 5.6 4.9 6.6 6.7 37.2 9.7 6.5 5.5 20.8 12.7 15.4 2.4 44.6 13.2 18.1 6.3 16.7 7.6 16.6 11.8 5.6 16.2 5.2 8.3 7.0 9.1 21.2 13.2 17.0 5.5 20.4 18.7 22.4 5.9 9.5 10.9 32.9 3.6 18.2 4.6 19.3 12.8 12.2 4.7 17.8 60.2 3.8 7.2 21.8 5.0 6.7 5.5 6.6 10.7 2.7 5.3 23.8 5.1 13.6 3.8 0.8 2.2 2.2 6.9 2.1 3.3 3.5 3.0 3.7 1.4 6.0 1.2 2.0 3.2 0.7 2.6 1.9 3.6 3.4 21.6 33.3 18.1 30.5 21.1 16.5 30.3 25.6 22.7 17.3 35.9 51.7 13.4 9.6 12.6 14.0 22.4 3.6 5.9 8.5 12.5 6.1 4.3 2.4 17.9 1.5 6.7 3.7 10.4 4.7 31.5 25.9 1.9 3.1 19.4 12.9 18.6 8.7 15.0 8.6 27.1 4.0 4.9 6.0 6.6 8.3 5.1 9.0 16.8 3.7 13.3 1.7 15.0 17.4 10.2 27.8 5.1 6.2 5.6 16.4 8.8 24.4 14.5 4.5 30.9 16.1 79.4 2.8 12.2 10.5 20.0 3.7 22.4 4.3 14.1 25.6 0.0 9.8 4.6 7.0 8.6 12.1 5.7 0.8 21.4 6.9 15.3 6.7 FARP2 "FIR, FRG, KIAA0793, PLEKHC3" ENSG00000006607 "FERM, ARH/RhoGEF and pleckstrin domain protein 2" O94887 2 241356285-241494841 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 128.2;Oligodendrocytes: 114.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031226, HPA055592" Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA031226: AB_10602808, HPA055592: AB_2682856" "unprognostic (3.07e-1)" "unprognostic (1.39e-1)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (2.51e-1)" "unprognostic (1.37e-2)" "unprognostic (1.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-1)" "unprognostic (2.19e-1)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (9.11e-2)" "unprognostic (6.31e-2)" "unprognostic (6.78e-2)" "unprognostic (2.74e-1)" "unprognostic (1.73e-1)" 9.6 10.3 13.8 11.4 16.8 5.4 9.0 19.3 16.0 10.0 9.8 22.6 20.2 10.6 7.3 14.1 9.2 10.0 7.6 13.2 12.9 11.0 17.1 10.4 11.9 15.6 15.2 11.0 11.4 13.2 8.4 9.0 15.6 10.1 21.3 10.1 9.2 10.0 10.6 22.6 18.9 11.6 11.7 11.6 20.3 28.1 16.2 8.5 6.8 9.9 13.8 14.2 10.1 21.3 20.0 14.3 25.8 17.7 21.9 29.1 23.1 19.7 16.3 20.0 20.6 15.3 23.4 8.5 5.2 38.8 14.1 22.4 35.0 20.6 30.4 13.3 18.1 18.8 25.4 20.3 16.0 17.0 14.1 29.3 15.2 29.2 23.7 9.3 18.4 16.1 21.7 7.6 16.3 16.7 18.3 12.5 12.8 35.3 11.1 20.3 58.2 25.7 25.9 41.0 30.5 20.3 22.1 15.4 59.5 14.9 8.1 16.8 27.9 18.8 14.3 23.8 16.0 13.0 10.0 18.8 17.2 11.5 39.0 6.1 2.1 7.3 1.3 5.1 1.2 4.4 1.4 1.5 3.1 4.9 0.9 1.0 1.3 1.7 2.8 6.4 2.2 1.6 13.8 16.8 19.3 16.0 13.2 12.9 15.6 15.2 15.6 11.7 16.2 21.3 8.9 28.9 5.9 27.4 23.9 15.4 11.4 8.0 16.5 12.7 11.1 8.3 29.6 14.3 12.3 18.4 18.8 5.8 9.7 36.3 3.9 9.3 42.7 12.0 10.6 10.5 28.1 3.4 43.1 12.3 5.4 12.9 45.3 14.0 6.3 15.9 11.0 11.6 4.2 20.2 36.7 38.7 10.2 8.4 9.4 25.0 14.9 11.9 39.2 38.4 8.5 4.9 2.1 128.2 114.0 12.6 24.1 10.5 14.4 12.8 20.9 7.1 17.3 15.1 19.7 21.4 14.1 45.6 19.7 13.8 15.2 11.1 6.0 11.3 26.2 22.4 FAXC "C6orf168, dJ273F20, MGC2817" ENSG00000146267 "Failed axon connections homolog, metaxin like GST domain containing" Q5TGI0 6 99271168-99350062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Excitatory neurons: 57.1;Inhibitory neurons: 60.1;Oligodendrocyte precursor cells: 43.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 26.0;HAP1: 23.8;SCLC-21H: 34.2;SH-SY5Y: 23.7;SK-MEL-30: 22.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039106 Uncertain Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA039106: AB_10697546" "unprognostic (8.03e-2)" "unprognostic (4.91e-2)" "unprognostic (5.04e-3)" "unprognostic (6.44e-2)" "unprognostic (3.80e-1)" "unprognostic (5.00e-3)" "unprognostic (7.56e-2)" "unprognostic (7.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.34e-2)" "unprognostic (2.79e-3)" "unprognostic (2.47e-3)" "unprognostic (6.70e-4)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.86e-2)" "unprognostic (3.49e-3)" 0.7 2.2 11.0 1.5 12.7 0.0 3.2 9.3 19.0 2.5 2.0 22.7 1.5 6.5 11.0 6.2 3.7 2.4 0.8 14.1 7.6 2.7 0.0 1.7 0.1 7.2 5.6 2.2 2.5 6.5 15.9 0.8 6.3 8.2 2.9 10.4 7.4 10.6 0.5 0.9 3.3 7.8 4.4 0.4 7.1 2.1 8.5 2.2 1.7 0.6 0.1 14.3 2.9 11.4 4.0 3.2 10.3 14.3 0.0 0.0 3.8 5.0 3.2 8.1 7.0 1.9 1.3 0.0 0.6 1.0 26.0 0.1 23.8 4.7 7.0 0.0 11.8 0.1 1.9 0.7 0.6 0.0 0.0 0.5 7.5 0.2 3.8 5.9 0.0 2.0 0.5 0.0 2.7 7.0 0.0 0.0 12.2 0.0 4.8 0.0 1.0 0.0 4.3 0.3 34.2 23.7 4.5 3.2 22.6 4.2 10.0 0.0 1.0 2.5 4.7 0.0 15.5 0.0 0.0 0.0 0.1 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 12.7 9.3 19.0 14.1 7.6 7.2 5.6 6.3 4.4 8.5 11.4 0.2 25.6 15.2 5.5 0.5 0.4 4.2 4.2 5.7 14.4 5.3 9.0 1.1 0.0 8.1 1.8 10.4 1.2 0.4 0.2 9.8 2.3 2.6 0.6 1.0 1.7 0.0 0.0 57.1 0.7 0.2 1.4 0.0 0.4 3.8 0.4 1.4 0.1 0.2 3.3 60.1 0.2 4.1 0.6 1.1 5.0 0.0 1.2 1.8 2.8 0.1 3.6 2.1 43.7 4.4 1.0 0.1 1.9 0.1 4.8 0.0 1.0 2.1 13.6 0.0 0.2 1.3 1.3 8.9 1.2 0.3 0.3 1.2 0.2 0.4 1.2 FBXO25 FBX25 ENSG00000147364 "F-box protein 25" Q8TCJ0 8 406428-477967 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 97.8" "Cell type enhanced" "Detected in all" "Early spermatids: 625.7;Late spermatids: 312.5;Spermatocytes: 640.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 58.7;SK-MEL-30: 61.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: B-cells - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.63e-1)" "prognostic favorable (5.38e-5)" "unprognostic (2.74e-2)" "unprognostic (5.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.25e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-3)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (2.39e-3)" "unprognostic (3.30e-1)" "prognostic favorable (1.41e-4)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (2.11e-3)" "unprognostic (2.41e-1)" 14.4 20.4 9.3 7.6 9.4 9.1 13.8 13.4 11.8 9.1 8.3 16.6 15.4 8.4 16.8 10.0 8.6 9.3 15.3 8.8 9.2 15.8 30.0 10.4 12.0 8.8 10.2 8.8 28.6 14.2 12.1 6.8 9.1 24.9 18.7 7.2 16.3 10.5 18.3 12.4 11.1 11.0 8.4 8.1 15.1 97.8 8.6 20.7 18.6 19.7 12.1 11.3 9.0 11.4 13.4 10.6 4.5 8.8 6.9 4.4 18.6 12.6 18.5 11.8 18.1 6.0 12.7 0.3 3.4 19.4 17.8 8.5 8.7 24.5 16.1 10.0 14.5 7.1 6.3 28.3 20.5 11.4 13.7 12.7 37.6 3.6 18.7 17.9 5.0 58.7 8.4 0.1 13.9 12.8 50.8 13.6 2.1 29.0 4.6 2.4 3.4 18.1 15.4 22.5 13.7 14.4 12.7 4.2 61.5 11.2 9.0 8.1 7.5 4.8 4.1 0.8 10.1 9.2 14.4 13.6 13.0 4.7 14.7 1.6 9.1 6.6 9.0 10.8 11.1 16.2 10.7 8.5 9.1 10.9 9.5 9.4 0.7 9.9 9.9 9.0 12.5 6.9 9.3 9.4 13.4 11.8 8.8 9.2 8.8 10.2 9.1 8.4 8.6 11.4 21.3 19.2 28.5 15.3 24.2 34.8 19.6 28.0 19.9 31.8 35.9 21.7 36.6 42.9 20.4 35.0 10.4 20.0 26.8 30.4 72.4 53.3 625.7 20.0 17.8 25.7 43.3 12.6 20.5 102.6 18.9 18.2 16.3 27.4 20.3 15.4 28.2 77.0 25.4 53.8 20.0 58.2 42.7 32.7 24.2 312.5 38.8 17.4 39.2 11.2 36.2 22.1 38.1 8.5 28.3 51.5 41.2 29.3 21.4 39.1 34.9 58.3 13.2 36.3 26.3 17.8 16.2 640.9 142.1 17.4 40.5 16.1 19.5 14.4 47.2 21.8 FBXO44 "FBG3, FBX30, Fbx44, Fbxo6a, MGC14140" ENSG00000132879 "F-box protein 44" Q9H4M3 1 11654375-11663327 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 144.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 48.2;Inhibitory neurons: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003363 Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA003363: AB_1078831" "unprognostic (1.39e-1)" "unprognostic (1.34e-1)" "unprognostic (9.59e-2)" "unprognostic (5.34e-2)" "unprognostic (2.82e-1)" "unprognostic (2.97e-2)" "unprognostic (2.44e-1)" "unprognostic (1.31e-2)" "unprognostic (3.32e-1)" "unprognostic (1.93e-1)" "prognostic favorable (2.63e-4)" "unprognostic (2.57e-2)" "prognostic favorable (6.29e-5)" "unprognostic (1.34e-2)" "unprognostic (5.45e-1)" "unprognostic (1.77e-1)" "unprognostic (3.02e-3)" 19.1 37.1 114.2 12.5 118.5 8.2 26.9 112.6 144.5 38.8 76.3 26.8 19.9 20.9 13.4 23.7 32.4 14.5 35.1 120.6 105.3 58.7 39.9 22.3 25.2 108.1 99.8 32.0 41.4 45.5 90.5 3.1 105.1 54.5 4.2 18.0 35.2 19.4 11.4 42.7 27.6 7.9 89.2 38.6 30.1 29.0 111.1 10.1 50.2 8.8 14.0 26.1 36.8 115.6 14.9 23.3 8.2 31.6 11.8 12.4 10.9 11.0 13.9 12.1 10.7 17.0 26.6 0.3 25.7 12.4 20.6 3.3 16.5 37.4 5.0 16.1 21.1 0.4 14.0 27.9 16.2 0.2 2.0 15.9 24.7 11.4 8.7 24.9 9.6 27.4 8.5 3.5 3.1 8.8 24.2 2.4 8.7 12.9 16.5 9.8 0.1 4.8 19.7 5.2 24.8 20.7 29.7 11.3 51.1 10.1 20.4 12.9 12.1 8.8 21.4 12.2 9.1 23.1 13.9 9.3 19.7 5.9 21.0 1.8 2.3 0.7 13.0 2.7 10.0 11.0 8.6 9.8 3.8 11.5 11.6 7.9 1.8 1.8 3.0 5.7 8.6 7.4 114.2 118.5 112.6 144.5 120.6 105.3 108.1 99.8 105.1 89.2 111.1 115.6 3.4 0.0 7.4 27.1 18.3 18.4 12.5 20.1 25.0 21.5 15.7 18.0 4.3 8.6 10.1 16.5 14.6 1.3 18.3 1.2 31.3 7.8 4.5 2.3 4.4 4.3 4.2 1.3 48.2 6.5 2.5 12.3 7.7 2.1 3.8 10.7 8.6 5.4 6.1 40.4 50.1 1.9 14.2 5.3 11.4 13.7 23.0 5.8 10.6 6.5 4.7 15.6 16.5 22.1 18.2 7.0 1.7 29.0 9.7 10.8 1.7 11.9 5.4 7.2 0.0 6.4 6.6 11.1 6.7 7.6 17.0 0.8 18.2 4.5 2.9 5.9 FBXO7 "Fbx, FBX7, PARK15" ENSG00000100225 "F-box protein 7" Q9Y3I1 22 32474676-32498829 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 279.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 680.9;Late spermatids: 620.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032113, HPA032114, CAB034296" Uncertain Supported Nucleoplasm,Cytosol NA NA 550000 "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Cytosol" "CAB034296: AB_2102563, HPA032113: AB_2674156, HPA032114: AB_10696202" "unprognostic (3.99e-2)" "unprognostic (1.53e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.36e-1)" "unprognostic (2.82e-1)" "unprognostic (2.11e-2)" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.45e-2)" "unprognostic (2.28e-1)" "unprognostic (2.53e-1)" "prognostic favorable (2.66e-10)" "unprognostic (3.33e-2)" "unprognostic (1.65e-1)" "unprognostic (7.02e-2)" "unprognostic (1.79e-3)" 51.6 61.7 70.3 35.9 86.8 279.9 52.9 79.9 86.5 53.5 72.3 53.5 47.7 49.2 68.7 40.1 66.6 43.9 38.5 68.3 76.2 106.5 128.4 59.6 54.6 85.0 83.8 62.7 41.0 75.9 50.6 71.5 84.1 42.6 53.8 40.1 43.1 53.5 31.0 50.6 48.4 57.1 79.0 65.6 48.4 99.5 79.8 77.9 134.2 48.3 61.8 54.8 44.0 97.8 72.1 52.1 69.3 77.1 105.8 99.5 45.9 64.3 119.6 102.7 121.9 54.4 51.1 71.2 49.6 114.6 87.8 47.6 103.3 84.7 105.1 111.8 80.9 99.1 54.4 83.7 126.8 126.2 82.8 83.8 134.1 90.6 69.2 93.4 112.2 53.1 77.5 88.0 112.7 57.7 65.3 81.2 26.7 102.3 36.1 64.1 72.2 84.0 118.2 81.0 96.6 63.1 81.3 62.4 235.2 98.3 34.0 67.2 76.0 50.6 69.4 48.4 49.5 62.1 69.3 67.6 97.4 65.6 212.3 251.5 59.9 132.1 83.3 70.6 101.5 70.2 75.9 84.9 82.2 63.6 65.6 72.6 22.4 98.3 74.9 55.8 101.3 90.4 70.3 86.8 79.9 86.5 68.3 76.2 85.0 83.8 84.1 79.0 79.8 97.8 48.8 41.7 25.3 37.9 60.4 46.3 69.4 72.7 48.9 26.0 46.5 32.3 16.1 65.8 48.1 49.7 18.8 90.2 73.6 43.4 97.8 75.3 303.3 41.3 37.8 53.1 67.6 680.9 27.6 77.4 108.9 47.9 40.2 47.2 55.8 63.6 53.9 88.6 71.9 33.7 26.7 42.7 65.1 64.8 53.2 620.8 45.1 55.0 119.2 28.1 125.2 54.1 72.1 101.0 170.6 77.2 58.0 48.9 62.7 68.3 72.2 152.9 34.2 38.1 46.0 35.3 46.2 149.4 136.9 42.3 43.3 71.6 62.3 41.8 47.2 83.7 FGFBP2 KSP37 ENSG00000137441 "Fibroblast growth factor binding protein 2" Q9BYJ0 4 15960245-15969309 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.0;bone marrow: 54.6" "Group enriched" "Detected in many" 6 "dendritic cells: 486.6;NK-cells: 1627.2" "Group enriched" "Detected in many" 9 "glioma: 4.8;head and neck cancer: 13.1;lung cancer: 16.7;melanoma: 16.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 551.3;memory CD8 T-cell: 332.1" "Lineage enriched" "Detected in many" 8 "T-cells: 551.3" "Cell line enhanced" "Detected in some" "SK-MEL-30: 6.9;T-47d: 3.2;WM-115: 1.3" "Secreted to blood" NA NA 346000000 36000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.51e-3)" "unprognostic (8.81e-3)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-2)" "unprognostic (1.54e-1)" "unprognostic (6.14e-2)" "unprognostic (1.35e-2)" "unprognostic (9.89e-2)" "unprognostic (1.76e-1)" "unprognostic (2.55e-2)" "unprognostic (3.33e-1)" "unprognostic (3.51e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (9.61e-2)" "unprognostic (1.49e-2)" 29.0 1.5 0.9 0.4 1.0 54.6 12.7 0.8 1.5 0.6 0.8 11.8 0.1 0.5 7.2 0.6 0.7 0.9 23.6 1.0 1.1 0.5 1.2 8.5 2.9 0.9 0.8 0.4 0.2 0.3 0.2 0.5 0.9 1.4 0.9 1.1 8.6 0.9 1.1 21.0 2.0 0.3 0.8 14.0 1.7 8.6 0.9 5.3 1.1 3.6 1.0 2.8 1.8 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 6.9 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.3 3.5 0.8 2.4 551.3 1.3 5.2 0.8 128.6 332.1 0.9 0.4 47.3 314.1 8.4 64.9 1.6 2.1 0.9 371.2 0.9 1.0 0.8 1.5 1.0 1.1 0.9 0.8 0.9 0.8 0.9 0.9 2.6 0.0 5.3 0.0 2.6 9.6 0.0 0.2 0.0 0.0 1.5 1.7 1.5 5.7 1.4 5.5 8.4 0.6 486.6 0.1 0.0 0.7 1.3 0.9 0.1 2.2 0.0 3.6 0.0 0.0 0.0 19.9 0.5 0.3 3.8 60.3 6.1 0.6 0.0 0.0 0.0 0.4 0.0 4.9 12.0 3.0 0.0 2.2 46.2 0.0 5.8 1.4 1627.2 0.0 0.1 0.2 0.0 0.4 17.5 0.0 0.0 1.3 1.3 0.4 0.0 1.8 2.5 0.7 0.1 0.1 7.7 1.0 167.2 0.2 0.1 0.0 FMN1 "DKFZP686C2281, FLJ45135, FMN, LD, MGC125288, MGC125289" ENSG00000248905 "Formin 1" Q68DA7 15 32765544-33194714 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;retina: 30.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 117.0;Cone photoreceptor cells: 221.0;Excitatory neurons: 439.4;Inhibitory neurons: 340.0" "Cancer enriched" "Detected in many" 9 "melanoma: 14.5" "Region enriched" "Detected in some" 7 "cerebral cortex: 16.9" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 21.4;RH-30: 26.9;SK-MEL-30: 28.7;T-47d: 24.8;U-138 MG: 17.2;U-2197: 17.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005465, HPA046786" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA005465: AB_1859515, HPA046786: AB_10963545" "unprognostic (1.57e-1)" "unprognostic (5.92e-3)" "unprognostic (1.96e-1)" "unprognostic (2.10e-3)" "unprognostic (3.67e-2)" "unprognostic (3.00e-2)" "unprognostic (1.56e-2)" "unprognostic (2.84e-2)" "unprognostic (3.44e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-3)" "unprognostic (3.53e-1)" "unprognostic (4.89e-2)" "unprognostic (2.89e-2)" "unprognostic (3.73e-1)" "unprognostic (4.32e-1)" "unprognostic (7.61e-2)" 1.8 0.8 0.0 2.4 0.0 1.2 3.0 0.0 16.9 5.3 0.0 5.7 1.3 1.0 0.7 2.0 3.1 2.4 0.9 0.0 0.0 2.8 0.5 3.4 0.9 2.3 0.0 0.2 1.2 1.4 3.7 3.7 0.0 1.8 4.4 30.0 4.2 1.2 0.7 4.2 1.8 2.2 0.0 1.0 7.9 10.2 1.7 3.8 2.5 0.5 0.6 1.3 3.6 0.0 3.8 4.0 0.8 0.4 0.1 0.4 4.9 5.4 4.1 1.5 4.0 0.6 5.0 0.6 1.8 6.1 3.4 3.7 0.1 3.7 3.9 0.0 0.2 3.1 0.8 0.4 0.2 0.0 0.2 1.5 0.2 7.9 0.1 3.1 0.0 0.1 0.0 21.4 8.8 3.9 0.1 0.0 1.1 7.0 0.3 0.6 26.9 4.9 1.8 1.5 0.3 0.9 0.0 3.3 28.7 0.9 24.8 0.0 4.9 17.2 2.7 17.9 1.6 0.0 0.0 0.9 7.3 0.2 10.1 1.3 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.2 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 2.3 0.0 0.0 0.0 1.7 0.0 0.4 41.7 46.9 10.1 1.6 3.7 3.2 2.0 3.4 117.0 7.7 5.1 3.1 14.3 17.3 0.0 221.0 12.0 5.4 13.3 11.7 5.7 16.5 17.4 2.4 2.7 9.0 0.4 439.4 1.8 5.9 2.6 97.9 7.0 24.0 1.8 0.0 0.4 10.9 47.1 340.0 16.8 16.2 28.0 3.9 12.8 0.9 29.6 33.8 64.6 5.8 6.9 0.0 8.0 61.9 11.4 11.4 0.7 2.2 4.5 4.0 1.6 29.4 102.4 0.0 13.0 1.0 18.4 16.0 7.3 3.4 18.3 5.0 0.1 9.9 5.7 GAS2L3 ENSG00000139354 "Growth arrest specific 2 like 3" Q86XJ1 12 100573683-100628288 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;monocytes: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 4 "spinal cord: 13.8" HPA048593 Approved NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA048593: AB_2680455" "unprognostic (1.03e-1)" "unprognostic (5.13e-2)" "unprognostic (5.10e-2)" "unprognostic (2.70e-2)" "unprognostic (2.32e-2)" "unprognostic (1.46e-1)" "unprognostic (1.04e-7)" "unprognostic (2.79e-3)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (9.21e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.58e-7)" "unprognostic (1.34e-1)" "unprognostic (2.35e-1)" "unprognostic (3.60e-2)" "unprognostic (6.67e-2)" 1.8 0.8 0.1 1.6 1.4 5.6 0.8 0.1 0.7 1.2 0.5 3.3 2.7 0.7 0.4 1.6 0.3 4.8 1.5 0.5 0.1 1.3 1.0 2.5 1.3 0.5 0.5 1.1 0.5 0.2 0.2 3.5 0.5 0.3 3.8 0.4 0.5 1.1 0.8 3.4 2.7 1.6 0.3 1.4 1.4 4.0 1.4 0.9 0.6 1.2 1.2 1.6 0.5 1.1 35.4 14.0 18.6 14.8 5.7 7.3 6.2 16.2 15.3 21.3 23.8 10.4 9.5 0.6 4.8 12.8 20.8 11.8 12.0 5.9 31.0 10.0 9.1 0.0 12.2 7.0 1.9 0.0 8.0 2.9 0.6 12.8 36.1 10.1 20.2 0.0 2.2 0.0 17.7 10.4 0.0 0.2 5.9 6.5 16.7 2.4 32.5 0.8 9.2 9.6 8.4 8.1 17.0 11.7 22.2 6.5 21.3 1.9 13.6 13.6 14.3 12.2 17.8 7.4 9.3 0.0 5.3 5.6 39.3 0.3 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.1 0.1 1.4 0.1 0.7 0.5 0.1 0.5 0.5 0.5 0.3 1.4 1.1 3.6 0.0 0.0 1.0 0.2 3.4 0.4 0.5 2.8 0.2 2.0 2.2 2.0 11.5 0.2 0.0 0.0 9.9 0.4 9.8 0.0 2.7 4.5 3.6 5.5 5.6 3.6 6.9 2.5 0.7 4.5 2.2 11.2 7.4 1.3 7.2 2.5 1.4 13.9 0.0 5.9 14.2 0.0 8.0 11.1 0.5 0.6 14.7 7.2 4.7 1.5 2.2 0.0 2.5 0.3 0.3 8.2 0.7 0.3 0.6 2.6 3.4 1.0 0.1 0.0 4.8 2.7 16.0 2.3 4.7 3.7 33.9 1.0 6.8 8.3 0.6 GJB1 "CMTX, CMTX1, CX32" ENSG00000169562 "Gap junction protein beta 1" P08034 X 71212811-71225516 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 100.9;liver: 335.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 114.4;Hepatocytes: 286.4;Proximal enterocytes: 118.8;Proximal tubular cells: 68.9;Undifferentiated cells: 66.1" "Cancer enhanced" "Detected in many" "liver cancer: 163.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 143.2;SK-MEL-30: 155.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012994 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "CAB012994: AB_2533228" "unprognostic (2.09e-2)" "unprognostic (1.39e-1)" "unprognostic (8.78e-2)" "unprognostic (2.71e-3)" "unprognostic (2.70e-1)" "unprognostic (4.11e-1)" "unprognostic (2.92e-1)" "unprognostic (3.68e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (7.36e-3)" "unprognostic (1.80e-1)" "prognostic favorable (2.85e-6)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (7.79e-2)" "unprognostic (4.97e-2)" 0.1 0.0 27.1 3.7 63.2 0.0 6.4 76.5 37.6 8.8 12.7 33.9 44.0 1.7 22.5 0.3 27.4 41.5 0.0 27.3 40.9 42.9 335.7 2.4 0.0 90.6 64.4 0.1 83.0 0.0 0.1 0.0 76.0 11.6 23.8 0.0 37.7 7.5 0.0 0.9 34.4 1.8 50.0 0.1 16.4 10.2 56.9 0.0 0.1 0.1 0.0 0.4 0.1 100.9 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 25.5 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 143.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.3 0.0 5.1 0.2 0.0 0.2 0.0 0.0 155.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.1 63.2 76.5 37.6 27.3 40.9 90.6 64.4 76.0 50.0 56.9 100.9 0.0 0.0 4.8 0.3 0.8 0.6 0.7 0.5 0.0 0.0 7.7 2.4 0.1 114.4 2.7 9.2 0.0 0.0 0.1 50.2 9.8 34.1 0.3 8.2 3.4 0.6 9.6 8.0 0.2 58.9 0.0 0.1 15.8 29.0 4.5 0.0 3.3 286.4 0.0 0.0 0.2 29.4 2.0 4.8 0.4 0.4 0.3 0.8 23.2 0.0 0.6 0.0 0.0 1.0 51.3 32.3 53.4 0.4 0.0 2.6 118.8 68.9 0.1 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.1 0.0 1.0 0.0 66.1 2.8 GJC3 "CX30.2, GJE1" ENSG00000176402 "Gap junction protein gamma 3" Q8NFK1 7 99923266-99929620 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 8.7;pancreas: 11.1;salivary gland: 11.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 36.3;Breast myoepithelial cells: 26.9;Exocrine glandular cells: 24.0;Pancreatic endocrine cells: 12.8;Prostatic glandular cells: 13.0" "Group enriched" "Detected in many" 5 "breast cancer: 3.8;melanoma: 3.0;prostate cancer: 3.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 1.3;SK-MEL-30: 2.3;U-2197: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015024 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" "HPA015024: AB_1847132" "unprognostic (9.31e-2)" "unprognostic (6.43e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-1)" "unprognostic (7.25e-2)" "unprognostic (2.54e-1)" "unprognostic (2.88e-2)" "unprognostic (7.68e-2)" "unprognostic (9.14e-2)" "unprognostic (6.71e-2)" "unprognostic (4.78e-2)" "unprognostic (1.20e-1)" "unprognostic (3.88e-3)" "unprognostic (1.14e-1)" "unprognostic (4.17e-1)" "unprognostic (3.49e-1)" "unprognostic (5.81e-3)" 1.6 0.5 0.8 0.1 0.9 0.1 8.7 0.1 1.2 0.3 0.0 0.5 0.4 0.2 0.0 0.2 0.3 0.3 0.4 0.9 0.3 1.0 2.7 0.2 0.2 0.2 0.4 0.4 11.1 0.0 0.4 1.0 0.2 4.6 0.0 1.0 11.7 0.1 0.2 2.6 0.3 0.2 0.0 0.3 1.4 1.7 0.6 0.1 0.3 0.2 0.0 0.3 0.3 0.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.0 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.9 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.5 0.6 0.1 0.5 0.2 0.4 1.1 1.3 0.0 0.0 0.4 0.3 0.0 0.4 0.1 0.2 0.1 0.3 2.3 0.5 0.7 0.0 0.3 0.1 0.4 1.8 0.1 0.1 0.5 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.9 0.1 1.2 0.9 0.3 0.2 0.4 0.2 0.0 0.6 0.5 1.1 3.2 3.7 0.0 0.4 0.3 4.9 1.4 0.0 0.0 36.3 26.9 0.0 4.3 2.1 1.8 0.0 0.0 0.6 0.0 1.9 0.4 0.4 0.0 0.0 1.5 1.2 0.0 0.7 24.0 0.0 0.2 0.0 0.0 4.5 0.2 1.1 5.0 0.1 0.0 0.4 0.1 8.2 0.0 0.3 1.1 0.3 0.1 0.0 0.0 0.6 4.0 0.0 0.0 0.6 12.8 0.0 0.0 0.0 13.0 0.0 9.7 0.3 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 9.4 GLRX2 "bA101E13.1, GRX2" ENSG00000023572 "Glutaredoxin 2" Q9NS18 1 193090866-193106114 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 17 "Early spermatids: 796.4;Late spermatids: 1841.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 240.2" "Low region specificity" "Detected in all" "HPA023087, HPA057224" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Vesicles "HPA023087: AB_1849778, HPA057224: AB_2683373" "unprognostic (4.80e-2)" "unprognostic (3.77e-2)" "unprognostic (8.04e-2)" "unprognostic (2.33e-1)" "unprognostic (1.13e-1)" "unprognostic (4.99e-2)" "unprognostic (2.40e-3)" "unprognostic (5.11e-2)" "unprognostic (3.21e-2)" "unprognostic (2.38e-2)" "unprognostic (1.10e-2)" "unprognostic (2.38e-1)" "prognostic unfavorable (3.30e-7)" "unprognostic (6.23e-2)" "unprognostic (1.73e-1)" "unprognostic (6.21e-2)" "unprognostic (4.48e-2)" 16.1 22.3 16.0 7.9 16.5 9.5 12.4 17.0 28.7 10.2 15.4 14.4 11.7 8.2 10.7 16.7 7.2 6.9 37.0 16.5 18.2 16.2 25.9 9.8 5.2 17.3 15.8 6.2 9.6 5.5 8.4 7.5 17.9 17.9 9.0 2.5 11.1 8.4 37.6 12.9 10.6 8.7 15.9 9.8 12.9 30.2 16.8 3.8 7.2 24.8 7.3 13.9 11.7 17.2 47.2 57.8 14.6 32.8 52.2 33.9 24.0 67.2 29.8 55.6 45.9 36.3 44.2 20.0 36.1 28.6 67.1 44.4 17.5 39.4 56.7 45.6 30.4 40.4 39.0 42.6 55.9 32.8 39.0 23.1 33.8 76.5 38.4 21.6 35.7 13.7 60.8 21.9 68.4 66.3 26.9 60.6 16.8 75.6 38.2 23.7 22.9 48.3 53.7 31.4 13.8 12.4 26.9 81.2 240.2 21.6 35.2 37.5 21.6 42.8 11.2 93.7 70.5 42.6 48.7 41.4 40.8 38.1 61.2 13.6 18.8 26.6 12.7 23.1 14.2 13.2 13.4 11.7 22.5 10.8 11.7 13.4 9.6 16.1 30.0 9.2 18.6 14.5 16.0 16.5 17.0 28.7 16.5 18.2 17.3 15.8 17.9 15.9 16.8 17.2 24.2 9.6 10.1 5.5 14.8 18.2 21.1 39.1 14.2 7.2 21.7 23.6 62.8 12.8 21.5 16.5 6.2 39.2 19.5 25.8 29.4 41.1 796.4 16.1 24.2 18.7 13.8 15.6 11.3 41.4 41.6 25.2 14.8 17.7 46.9 16.4 11.0 30.3 44.2 1.7 10.1 26.5 32.6 15.0 26.9 1841.1 17.4 26.8 26.6 5.6 25.9 9.9 28.8 5.0 10.1 38.3 31.5 18.0 20.5 39.2 40.3 74.3 13.9 11.5 6.6 15.5 36.2 12.3 25.4 21.3 19.9 24.8 14.0 33.1 24.1 20.5 GOLGA7B "bA451M19.3, bA459F3.4, C10orf132, C10orf133" ENSG00000155265 "Golgin A7 family member B" Q2TAP0 10 97849843-97871580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.0;choroid plexus: 26.2;epididymis: 23.4" "Cell type enhanced" "Detected in many" "Astrocytes: 25.5;Excitatory neurons: 33.6;Inhibitory neurons: 21.2;Late spermatids: 16.6;Rod photoreceptor cells: 18.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.3;GAMG: 14.5;HDLM-2: 5.7;SK-MEL-30: 22.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046878 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046878: AB_2679854" "unprognostic (7.90e-2)" "unprognostic (1.70e-3)" "unprognostic (7.10e-3)" "unprognostic (1.06e-2)" "unprognostic (8.97e-2)" "unprognostic (1.54e-1)" "unprognostic (6.20e-4)" "unprognostic (1.95e-1)" "unprognostic (4.45e-1)" "unprognostic (2.49e-1)" "unprognostic (8.89e-2)" "unprognostic (4.13e-2)" "unprognostic (1.15e-7)" "unprognostic (2.12e-1)" "unprognostic (1.47e-1)" "unprognostic (1.04e-3)" "unprognostic (5.90e-3)" 1.2 2.3 28.7 0.8 30.7 0.2 1.1 33.9 36.0 1.0 26.2 1.1 1.5 0.2 23.4 2.6 0.4 0.4 5.6 32.9 28.0 0.2 0.6 0.7 1.4 29.2 29.2 0.1 8.0 0.0 9.3 0.2 27.5 0.5 0.5 16.9 0.7 0.5 4.6 14.5 2.0 0.1 25.1 0.5 1.0 1.3 29.8 0.3 0.9 3.2 1.1 0.6 2.0 30.0 5.3 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 2.0 0.0 0.1 0.0 14.5 1.9 0.0 0.4 0.0 5.7 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 1.0 0.3 0.0 1.8 0.1 0.1 0.3 0.8 1.4 0.0 1.0 22.6 0.0 2.1 0.1 0.1 0.1 0.0 0.0 0.2 1.7 0.8 0.0 3.9 2.3 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 28.7 30.7 33.9 36.0 32.9 28.0 29.2 29.2 27.5 25.1 29.8 30.0 0.2 0.0 0.5 25.5 0.0 12.5 0.1 0.7 0.0 6.4 0.6 4.4 2.3 12.8 0.2 1.8 2.1 0.0 3.2 0.3 0.0 6.4 5.4 0.3 0.4 0.5 12.0 0.0 33.6 4.3 0.0 0.6 0.0 0.4 0.0 0.0 0.4 0.0 5.1 3.3 21.2 1.1 0.0 0.0 1.2 16.6 0.3 0.2 7.2 5.6 0.6 3.2 3.1 2.5 1.9 7.4 0.1 0.4 0.0 0.3 1.2 0.0 0.0 18.7 0.0 1.5 0.3 3.9 2.3 0.0 5.1 0.0 2.9 0.0 0.4 0.3 GORAB "FLJ11752, GO, NTKL-BP1, SCYL1BP1" ENSG00000120370 "Golgin, RAB6 interacting" Q5T7V8 1 170532131-170553834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027250, HPA027746" Approved Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "Nucleoplasm, Nucleoli, Cytosol" "HPA027250: AB_10611253, HPA027746: " "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (4.75e-3)" "prognostic favorable (1.39e-4)" "prognostic unfavorable (5.26e-4)" "unprognostic (8.48e-3)" "unprognostic (2.94e-2)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.77e-2)" "prognostic unfavorable (7.83e-12)" "unprognostic (2.52e-2)" "unprognostic (2.83e-1)" "unprognostic (7.71e-2)" "unprognostic (1.70e-1)" 3.1 5.2 1.6 1.9 1.6 0.6 2.8 1.6 3.1 3.8 1.9 3.6 1.4 3.2 3.5 2.3 2.1 2.1 3.1 1.5 2.3 2.5 4.3 2.5 3.6 1.6 1.8 4.3 3.7 1.9 3.0 3.1 1.7 2.8 3.3 1.3 3.3 2.6 1.1 1.9 2.7 2.0 1.7 3.1 2.1 2.0 2.0 2.8 3.0 2.1 3.0 3.1 3.3 1.8 3.4 3.8 4.5 2.0 9.0 5.8 2.9 4.8 7.5 3.6 4.6 1.9 4.9 5.1 6.1 4.3 2.4 4.0 6.4 2.8 6.0 4.8 1.6 2.5 4.0 2.8 4.9 4.4 3.1 4.4 2.5 4.2 3.9 5.5 3.5 2.3 4.4 2.3 5.3 0.6 5.8 4.0 4.7 6.2 4.0 3.9 3.8 6.0 4.2 1.9 1.4 3.0 3.6 4.8 11.5 3.1 2.7 8.4 4.4 6.8 3.1 2.9 7.2 3.5 4.4 3.8 5.2 4.0 5.4 0.7 3.9 0.0 2.3 4.2 3.9 2.8 4.1 3.5 4.3 2.8 3.6 3.0 0.5 3.8 3.1 2.7 5.3 2.6 1.6 1.6 1.6 3.1 1.5 2.3 1.6 1.8 1.7 1.7 2.0 1.8 8.1 0.0 11.4 8.8 8.9 2.8 4.0 6.5 8.6 4.7 5.2 7.1 9.4 10.0 7.1 5.5 2.1 6.0 6.2 12.8 3.9 12.3 2.3 5.5 10.4 8.3 0.0 3.4 9.3 6.0 7.3 10.5 9.2 6.7 13.9 5.2 5.3 6.6 7.1 5.0 7.7 9.4 8.2 6.9 4.6 3.2 14.0 5.6 3.6 3.7 10.1 4.3 3.1 9.0 7.3 5.7 9.8 6.4 10.3 4.9 4.3 6.0 2.4 7.1 6.6 8.2 9.3 13.1 8.1 5.4 1.6 5.6 6.3 5.1 6.4 3.0 GPATCH3 "FLJ12455, GPATC3" ENSG00000198746 "G-patch domain containing 3" Q96I76 1 26890488-26900467 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032078, HPA054973" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA032078: AB_10603671, HPA054973: AB_2682656" "unprognostic (2.93e-2)" "unprognostic (1.33e-2)" "unprognostic (7.34e-2)" "unprognostic (9.63e-2)" "unprognostic (1.42e-1)" "unprognostic (9.44e-2)" "prognostic unfavorable (1.23e-7)" "unprognostic (4.37e-2)" "unprognostic (7.75e-2)" "unprognostic (6.46e-2)" "prognostic favorable (6.42e-4)" "unprognostic (3.77e-1)" "unprognostic (3.22e-3)" "unprognostic (2.31e-2)" "unprognostic (3.81e-2)" "unprognostic (2.59e-1)" "unprognostic (6.82e-2)" 8.3 11.5 10.9 6.3 12.1 23.2 8.2 11.2 13.0 8.0 9.5 8.6 8.5 8.6 8.9 9.4 6.8 5.7 9.9 10.2 9.9 9.1 12.5 6.7 9.0 10.7 11.0 7.1 8.9 7.9 7.6 8.0 10.2 8.2 6.2 5.4 7.9 6.1 18.1 13.0 9.3 6.4 10.4 11.8 9.9 10.8 11.2 9.3 7.5 12.4 7.5 8.5 7.6 12.9 12.5 9.9 9.4 14.5 8.9 8.5 12.7 9.4 10.9 18.6 16.2 12.1 14.6 11.4 10.3 9.6 9.7 12.6 15.8 17.8 9.9 13.0 18.1 22.5 22.3 25.2 11.9 15.2 14.6 12.5 15.7 18.3 10.1 8.2 12.1 14.9 26.7 15.0 7.8 9.2 13.5 28.2 21.5 14.4 12.2 16.6 13.5 18.0 9.2 6.5 12.2 14.6 18.8 16.0 27.9 10.1 14.3 14.5 12.9 11.8 13.9 16.2 10.7 19.0 27.4 15.2 10.6 21.6 10.6 30.3 17.9 22.3 16.2 14.6 13.1 12.5 13.3 14.2 18.7 11.9 13.6 13.0 7.8 9.8 19.0 14.2 12.6 14.4 10.9 12.1 11.2 13.0 10.2 9.9 10.7 11.0 10.2 10.4 11.2 12.9 5.4 3.2 3.9 1.6 11.7 9.7 4.8 5.6 8.0 6.4 7.0 4.7 4.0 1.5 3.7 0.0 12.5 15.5 10.3 11.6 5.9 10.9 2.2 4.5 4.1 8.1 11.3 6.9 3.5 12.5 10.0 5.3 11.2 6.1 5.7 7.8 8.2 6.2 11.2 5.0 3.0 4.7 6.1 9.4 7.5 1.4 5.3 10.0 8.8 1.9 15.3 6.6 12.3 3.5 3.5 10.6 7.5 7.2 8.3 4.3 10.4 7.4 3.1 5.5 6.6 6.6 5.9 12.5 25.3 8.3 9.8 30.1 11.2 6.6 6.2 4.9 GPM6B "M6B, MGC17150, MGC54284" ENSG00000046653 "Glycoprotein M6B" Q13491 X 13770939-13938638 "Predicted membrane proteins" "Differentiation, Neurogenesis, Osteogenesis, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 743.2;choroid plexus: 180.7;retina: 207.7" "Cell type enhanced" "Detected in many" "Astrocytes: 633.3;Excitatory neurons: 361.3;Melanocytes: 357.5;Muller glia cells: 1722.4;Oligodendrocyte precursor cells: 408.1;Oligodendrocytes: 1476.6" "Cancer enriched" "Detected in many" 5 "glioma: 192.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 220 "plasmacytoid DC: 77.7" "Lineage enriched" "Detected in single" 268 "dendritic cells: 77.7" "Cell line enhanced" "Detected in many" "AF22: 154.8;AN3-CA: 150.1;ASC TERT1: 74.2;HSkMC: 110.0;SK-MEL-30: 154.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002913 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "HPA002913: AB_2263553" "unprognostic (1.56e-2)" "unprognostic (3.42e-1)" "unprognostic (1.83e-1)" "unprognostic (3.70e-2)" "unprognostic (8.55e-2)" "unprognostic (2.75e-3)" "unprognostic (2.12e-2)" "unprognostic (1.92e-2)" "unprognostic (4.27e-2)" "prognostic favorable (2.67e-4)" "unprognostic (1.79e-2)" "unprognostic (4.78e-2)" "unprognostic (2.38e-3)" "unprognostic (8.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-2)" "unprognostic (2.00e-1)" 7.5 9.3 418.4 6.0 518.8 1.1 26.4 540.4 521.1 27.1 180.7 33.8 5.0 6.3 12.1 11.5 6.5 5.9 15.8 447.8 463.6 7.7 1.1 16.8 2.8 596.3 459.3 4.4 3.2 0.6 17.2 1.3 580.5 21.8 7.8 207.7 14.8 35.2 2.5 13.9 9.2 5.4 533.4 14.5 11.7 3.5 419.9 0.8 5.0 7.5 1.9 9.1 19.7 743.2 0.4 0.4 154.8 150.1 41.6 74.2 0.4 0.9 6.9 0.1 0.0 0.4 0.5 0.7 0.3 0.0 0.6 1.3 7.6 0.8 0.0 0.6 25.2 0.4 10.0 0.4 1.5 0.5 0.9 110.0 0.9 0.0 1.9 0.6 0.0 3.0 0.4 6.8 1.5 0.6 3.4 0.7 48.5 0.1 2.5 2.0 13.7 23.9 0.0 0.5 7.8 4.4 0.8 4.4 154.4 41.9 0.7 3.6 0.3 1.0 1.3 0.3 2.0 0.5 0.3 0.3 1.4 0.3 12.4 0.2 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.2 0.2 0.1 77.7 0.1 0.7 418.4 518.8 540.4 521.1 447.8 463.6 596.3 459.3 580.5 533.4 419.9 743.2 13.8 0.0 5.1 633.3 15.8 33.0 22.7 5.9 6.8 74.4 37.1 47.1 1.3 1.5 7.8 22.0 87.6 5.0 50.7 3.0 0.0 5.4 1.5 45.8 32.7 12.5 1.2 5.3 361.3 3.7 3.7 54.2 0.0 30.4 4.5 19.7 10.8 0.4 1.2 26.9 144.0 5.0 8.2 1.9 33.5 3.2 24.2 3.7 357.5 40.3 4.6 1722.4 50.4 408.1 1476.6 2.3 6.0 32.0 7.3 26.5 6.1 1.1 11.0 151.4 46.0 137.7 43.6 9.6 13.3 7.0 17.0 13.7 20.5 8.6 3.2 14.8 GPR137B TM7SF1 ENSG00000077585 "G protein-coupled receptor 137B" O60478 1 236142505-236221865 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 135.6" "Cell type enhanced" "Detected in many" "Langerhans cells: 139.0;Muller glia cells: 226.0;Proximal tubular cells: 115.1;Rod photoreceptor cells: 171.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 17.6" "Group enriched" "Detected in many" 5 "granulocytes: 17.6;monocytes: 7.3" "Cell line enhanced" "Detected in many" "ASC diff: 82.8;SK-MEL-30: 220.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026422 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "HPA026422: AB_1849338" "unprognostic (1.59e-3)" "unprognostic (6.89e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (6.49e-2)" "unprognostic (2.42e-1)" "unprognostic (1.96e-1)" "unprognostic (5.54e-2)" "unprognostic (1.41e-1)" "unprognostic (5.06e-2)" "unprognostic (2.73e-2)" "unprognostic (5.53e-2)" "unprognostic (4.77e-2)" "unprognostic (2.83e-2)" "unprognostic (3.16e-1)" "unprognostic (7.02e-2)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" 15.8 6.9 33.4 15.4 39.4 6.4 13.7 35.6 39.8 25.2 18.8 11.4 9.7 19.1 39.9 9.1 6.1 20.3 22.2 32.8 35.4 68.1 22.1 16.7 18.4 36.9 38.3 12.2 3.7 13.1 3.3 30.0 37.3 10.4 10.8 135.6 6.2 14.7 1.4 18.8 8.7 15.9 34.2 16.4 11.0 3.5 37.3 6.3 15.1 5.0 16.9 28.7 13.2 38.1 5.6 7.8 6.4 5.7 82.8 46.6 2.0 12.3 27.5 7.4 10.3 1.8 6.7 0.9 19.1 13.0 16.7 4.3 8.4 7.6 7.2 5.4 15.8 3.2 1.0 1.4 11.7 4.3 29.7 30.5 25.4 5.7 2.8 23.3 12.0 7.6 0.5 0.1 12.6 6.7 3.6 1.7 3.1 2.4 2.9 6.1 10.0 2.4 10.8 20.1 4.6 9.3 4.2 16.9 220.5 4.9 22.1 7.5 10.7 11.2 7.8 26.2 12.1 1.0 7.2 0.8 6.7 3.1 17.3 17.6 0.9 9.6 0.9 4.1 0.4 0.5 0.6 2.7 1.1 0.3 0.3 0.8 0.1 0.1 7.3 0.3 1.7 0.4 33.4 39.4 35.6 39.8 32.8 35.4 36.9 38.3 37.3 34.2 37.3 38.1 7.3 0.0 1.7 17.6 10.3 25.7 22.2 8.0 14.2 31.9 8.2 4.8 23.0 7.2 5.1 12.9 35.5 46.7 9.7 1.1 17.6 14.4 0.1 1.9 10.2 7.1 8.5 4.0 14.8 10.4 9.9 19.3 6.6 2.1 20.3 2.8 11.7 4.1 88.0 52.2 15.4 2.7 0.0 81.4 139.0 0.9 9.0 55.0 69.4 8.4 83.8 226.0 4.1 30.2 14.9 11.1 2.7 6.0 8.4 21.4 2.2 115.1 6.1 171.2 0.0 7.1 10.5 0.1 1.1 9.4 19.9 40.8 19.9 3.5 2.7 29.8 GPR143 OA1 ENSG00000101850 "G protein-coupled receptor 143" P51810 X 9725346-9786297 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.2;choroid plexus: 14.4" "Group enriched" "Detected in many" 8 "Cytotrophoblasts: 40.6;Melanocytes: 126.3" "Cancer enriched" "Detected in all" 9 "melanoma: 84.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 3.1" "Lineage enriched" "Detected in single" 19 "granulocytes: 3.1" "Cell line enriched" "Detected in some" 7 "SK-MEL-30: 159.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA003648 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA003648: AB_2667028" "unprognostic (4.60e-2)" "prognostic favorable (8.73e-4)" "unprognostic (7.43e-3)" "unprognostic (5.41e-2)" "unprognostic (4.62e-3)" "unprognostic (2.00e-2)" "unprognostic (3.05e-1)" "unprognostic (2.64e-3)" "unprognostic (3.78e-1)" "unprognostic (5.89e-2)" "unprognostic (8.18e-2)" "unprognostic (8.40e-2)" "prognostic favorable (2.45e-5)" "unprognostic (2.75e-1)" "unprognostic (2.07e-1)" "unprognostic (8.76e-2)" "unprognostic (1.59e-2)" 0.6 1.1 10.6 0.1 13.0 0.0 1.7 11.8 11.5 2.0 14.4 1.4 0.5 3.2 5.3 2.4 2.8 0.9 0.1 10.8 13.1 4.6 1.7 1.0 0.5 12.6 14.2 3.3 1.2 2.9 2.7 6.1 12.3 2.6 1.4 0.9 3.3 4.4 0.0 8.9 0.5 1.0 11.4 0.0 0.7 0.8 13.1 1.8 3.2 0.0 1.6 1.1 1.1 12.2 1.9 0.4 4.6 0.2 0.0 0.0 3.7 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.2 0.0 0.4 0.1 0.2 1.1 0.1 0.1 0.3 0.0 0.2 0.6 2.3 0.0 3.4 0.1 1.6 0.0 0.0 24.2 6.7 0.0 0.0 0.0 0.0 12.1 0.0 0.1 11.1 0.0 0.1 0.0 0.1 0.1 22.2 3.2 0.9 0.0 0.3 0.0 159.6 10.8 1.9 0.0 4.6 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 3.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 10.6 13.0 11.8 11.5 10.8 13.1 12.6 14.2 12.3 11.4 13.1 12.2 0.1 0.0 0.0 9.8 0.2 5.5 1.3 1.8 2.2 0.5 2.1 1.7 0.9 0.0 4.9 7.3 0.0 40.6 0.0 0.8 1.9 4.9 0.2 1.7 1.6 1.5 0.0 0.0 0.6 0.6 2.1 1.0 0.0 1.3 0.0 1.8 2.9 0.3 4.8 0.0 0.3 0.8 2.0 0.0 1.6 1.8 1.8 0.1 126.3 1.0 0.0 1.2 0.0 0.5 0.6 1.2 0.2 6.4 0.0 1.8 0.2 5.0 3.2 0.2 0.0 0.0 0.7 0.2 1.3 4.2 0.6 10.1 0.7 1.0 2.0 1.8 GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656099-109674836 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 149.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 382.8;Proximal tubular cells: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "eosinophil: 351.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 351.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Cytokinetic bridge" "HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "prognostic favorable (9.96e-5)" "unprognostic (1.96e-3)" "unprognostic (7.49e-2)" "unprognostic (9.92e-3)" "unprognostic (1.48e-1)" "unprognostic (1.08e-2)" "unprognostic (8.47e-2)" "unprognostic (3.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.76e-2)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" 22.3 31.1 19.7 15.3 23.7 5.9 22.5 19.1 23.8 24.5 40.0 45.4 149.5 22.6 24.3 31.3 22.2 17.8 33.5 19.2 19.9 45.9 41.2 14.6 11.8 20.7 20.9 42.9 21.2 57.8 18.6 7.6 20.2 25.8 38.5 12.5 21.2 41.0 92.4 20.6 99.4 25.7 21.1 30.2 28.8 15.1 20.1 9.9 27.7 45.5 15.6 36.8 28.8 20.2 13.5 6.0 10.5 78.9 23.0 35.1 13.4 4.3 34.1 9.8 12.8 43.3 1.5 12.5 16.1 19.1 19.3 13.6 27.1 14.4 6.2 18.9 0.0 27.4 23.5 38.8 37.1 9.5 31.8 22.3 14.0 12.6 0.0 27.5 8.1 31.7 12.8 18.4 6.9 12.7 8.1 41.9 8.2 56.3 31.9 16.9 5.8 18.5 38.8 9.6 7.4 17.6 0.2 68.2 54.9 7.8 18.6 20.1 3.6 11.4 44.0 12.5 6.3 27.0 51.4 1.1 37.1 13.9 32.5 11.9 14.5 351.7 12.2 14.5 7.4 17.0 9.3 14.1 37.8 14.9 8.9 10.7 1.8 12.8 3.6 12.6 14.1 12.6 19.7 23.7 19.1 23.8 19.2 19.9 20.7 20.9 20.2 21.1 20.1 20.2 6.9 9.6 2.7 11.4 9.9 18.1 27.3 17.9 18.8 6.2 14.7 19.0 30.2 21.5 9.5 31.3 0.0 21.0 13.9 53.0 101.8 45.9 3.0 4.5 10.8 8.6 7.2 4.2 3.3 57.7 18.6 22.9 13.3 5.4 21.0 13.3 14.3 35.7 35.6 5.0 3.3 45.9 6.1 17.2 26.0 6.4 30.1 14.9 40.9 2.8 14.8 23.9 17.5 5.0 3.4 35.4 38.6 24.8 13.3 6.7 382.8 109.8 7.5 5.4 32.9 15.3 23.2 7.0 7.3 23.0 15.3 8.8 11.2 12.6 96.7 26.9 GSTO1 "GSTTLp28, P28" ENSG00000148834 "Glutathione S-transferase omega 1" P78417 10 104235356-104267459 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 657.7" "Cell type enhanced" "Detected in all" "Hofbauer cells: 676.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 1106.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037603, HPA037604" Enhanced NA NA 120000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 51: Myeloid cells - Hemostasis" "HPA037603: AB_2675574, HPA037604: AB_10672283" "prognostic favorable (6.95e-4)" "unprognostic (9.23e-2)" "unprognostic (1.43e-2)" "unprognostic (6.83e-2)" "unprognostic (7.16e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (9.23e-3)" "unprognostic (4.57e-2)" "unprognostic (7.65e-2)" "unprognostic (2.13e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.86e-2)" "unprognostic (1.29e-1)" "unprognostic (5.51e-3)" "unprognostic (5.82e-2)" 95.0 145.4 119.1 102.8 123.1 191.6 89.9 121.3 166.7 90.1 118.0 92.7 167.6 72.0 96.2 79.3 75.4 84.8 277.4 117.3 124.8 154.4 657.7 154.7 93.1 121.3 127.1 83.1 80.5 129.7 102.9 113.6 122.7 80.3 94.8 38.2 75.6 89.6 148.4 63.8 165.2 86.9 122.2 107.1 93.3 14.9 128.8 124.8 82.9 122.5 77.4 109.6 82.6 136.4 287.7 194.5 142.9 249.3 201.4 385.1 62.8 358.3 640.7 237.9 257.2 247.2 292.8 254.2 152.8 245.6 296.8 158.8 97.0 329.2 244.5 128.4 233.7 186.6 122.1 542.7 359.7 241.5 294.5 291.5 136.7 346.3 414.5 331.3 464.1 231.2 394.4 153.4 511.4 159.3 188.3 330.0 130.4 308.1 134.8 136.0 94.9 108.1 358.4 185.1 72.1 88.6 117.6 81.0 1106.0 238.2 92.0 192.7 426.6 276.9 143.6 427.3 328.4 2.7 3.3 2.0 517.7 416.2 112.0 842.8 532.4 157.9 133.0 457.0 164.5 148.8 164.6 172.9 429.3 111.9 143.0 144.3 151.8 185.0 369.1 203.0 204.8 632.1 119.1 123.1 121.3 166.7 117.3 124.8 121.3 127.1 122.7 122.2 128.8 136.4 107.4 76.9 72.6 8.8 64.8 93.7 328.2 297.6 51.2 36.9 63.5 105.5 328.2 218.8 113.3 101.2 20.9 394.2 82.0 101.6 332.6 341.0 22.4 68.1 79.6 164.5 103.5 192.8 12.1 248.4 176.6 173.0 49.5 81.7 146.3 107.6 388.0 628.2 676.5 23.5 11.7 163.8 124.1 321.8 223.6 17.3 114.6 484.5 126.3 8.4 277.7 81.2 95.8 8.5 21.8 347.6 150.7 112.8 39.9 169.4 483.2 538.0 114.3 29.8 151.2 85.3 176.1 5.7 5.1 55.8 78.7 111.0 81.4 224.8 196.6 204.9 GYG2 GN-2 ENSG00000056998 "Glycogenin 2" O15488 X 2828822-2882820 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 156.3" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Enteroendocrine cells: 20.4;Granulosa cells: 10.2;Hepatocytes: 20.2" "Cancer enhanced" "Detected in all" "melanoma: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 39.1;CACO-2: 30.4;Hep G2: 32.6;NTERA-2: 38.4;SK-MEL-30: 87.6;SuSa: 59.0" "Low region specificity" "Detected in all" "HPA005495, HPA064686" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli, Cytosol" Nucleoplasm "HPA005495: AB_1079035, HPA064686: AB_2685323" "unprognostic (4.45e-2)" "unprognostic (4.21e-2)" "unprognostic (6.41e-3)" "unprognostic (8.50e-2)" "unprognostic (2.07e-3)" "unprognostic (5.16e-1)" "unprognostic (1.74e-2)" "unprognostic (1.18e-1)" "unprognostic (7.43e-3)" "unprognostic (6.74e-2)" "prognostic favorable (3.01e-5)" "unprognostic (9.76e-2)" "unprognostic (6.10e-5)" "unprognostic (1.78e-1)" "unprognostic (5.05e-3)" "unprognostic (5.41e-2)" "unprognostic (6.60e-2)" 156.3 2.2 10.3 1.9 10.8 0.2 38.9 18.4 8.8 3.0 8.5 3.9 1.5 6.6 1.0 0.9 5.1 2.2 1.4 11.2 18.9 2.0 18.5 0.5 0.6 29.4 24.5 2.5 5.4 1.0 0.8 2.1 27.3 4.0 2.8 1.4 4.7 6.6 0.3 1.9 2.1 3.7 36.0 0.3 4.5 0.9 13.7 0.4 1.7 0.5 0.3 3.7 2.0 35.4 0.1 11.5 39.1 0.2 20.5 0.0 28.5 2.0 6.3 6.1 8.2 30.4 0.6 0.0 3.1 5.2 6.6 0.0 22.5 0.5 6.8 0.2 6.3 0.1 0.7 32.6 6.7 0.0 8.9 8.1 0.4 1.0 0.0 0.2 0.0 0.0 0.3 0.1 6.6 1.9 0.0 1.0 38.4 0.4 0.2 6.1 13.0 0.0 0.0 0.1 0.0 0.7 0.1 0.3 87.6 59.0 4.1 25.4 0.0 0.0 6.7 3.8 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.3 10.8 18.4 8.8 11.2 18.9 29.4 24.5 27.3 36.0 13.7 35.4 0.3 0.0 0.0 10.7 0.2 0.4 1.1 0.5 0.0 1.2 2.1 0.8 1.2 4.3 0.2 0.0 4.2 6.0 0.0 1.2 5.9 1.0 0.4 3.8 1.0 0.3 20.4 0.0 5.9 4.0 7.9 1.6 4.6 0.7 0.0 10.2 0.0 20.2 1.1 0.0 4.9 1.7 0.0 1.0 0.0 0.5 0.6 0.1 3.6 0.0 0.0 1.6 0.0 0.5 0.1 2.1 0.6 3.0 0.0 1.0 0.4 2.4 1.1 0.1 0.0 0.3 1.2 0.3 1.5 0.0 0.3 2.3 0.0 3.2 3.5 0.7 GYPC "CD236, CD236R, Ge, GPC, GYPD" ENSG00000136732 "Glycophorin C (Gerbich blood group)" P04921 2 126656133-126696667 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 1728.6;Hofbauer cells: 488.7" "Cancer enhanced" "Detected in all" "melanoma: 66.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 433.1;K-562: 362.1;SK-MEL-30: 668.4;U-266/70: 363.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008965, CAB009445" Enhanced Supported "Plasma membrane" NA NA 970000 "Cluster 20: T-cells - T-cell receptor" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "CAB009445: AB_2116251, HPA008965: AB_1078455" "unprognostic (1.63e-2)" "unprognostic (7.14e-3)" "unprognostic (8.39e-2)" "unprognostic (3.31e-3)" "unprognostic (4.19e-2)" "unprognostic (1.69e-2)" "unprognostic (8.82e-2)" "unprognostic (3.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-2)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-1)" "unprognostic (8.00e-3)" 172.3 73.0 17.3 51.5 17.6 441.0 109.2 17.5 30.8 75.7 20.2 89.1 18.2 62.3 20.2 42.3 68.4 56.3 161.9 16.5 20.2 58.4 18.5 101.4 110.5 22.2 18.4 91.5 34.8 9.6 16.9 50.3 22.0 46.5 19.3 10.3 26.4 56.1 212.7 37.0 52.9 55.9 20.6 98.5 41.0 7.3 23.6 59.6 33.3 204.1 75.9 73.0 54.4 24.9 1.3 0.0 152.0 0.2 116.1 100.5 0.2 24.0 186.4 28.9 84.9 0.0 0.2 0.6 0.4 69.6 107.6 0.3 85.7 0.1 9.5 79.7 0.0 279.0 0.0 0.0 433.1 99.0 0.7 237.4 0.0 23.1 0.1 2.3 1.0 190.4 362.1 214.6 70.5 0.0 0.1 148.9 46.7 0.0 0.4 18.1 12.1 0.4 11.8 0.0 0.2 0.0 0.3 0.0 668.4 20.7 0.0 258.5 65.7 107.3 1.0 7.3 1.2 363.9 257.4 0.5 51.4 135.8 99.3 0.8 28.6 2.2 153.1 40.3 172.2 95.8 136.7 186.5 50.0 102.6 190.5 188.3 21.9 81.1 24.7 27.1 179.4 119.0 17.3 17.6 17.5 30.8 16.5 20.2 22.2 18.4 22.0 20.6 23.6 24.9 260.7 6.4 7.7 0.7 152.7 38.0 3.4 17.0 43.3 0.6 14.6 110.5 34.9 84.4 6.0 14.7 2.1 4.9 194.0 0.0 135.0 202.9 1.6 3.6 99.8 157.2 0.0 1728.6 0.4 4.9 6.9 170.5 10.2 2.5 22.9 23.3 229.2 6.2 488.7 0.0 0.5 1.1 0.0 118.0 108.5 4.9 87.3 134.9 305.9 15.0 98.0 5.1 204.9 6.0 0.1 6.0 0.4 69.2 250.9 9.4 0.0 8.1 1.7 2.6 59.2 65.8 88.6 0.2 0.7 41.9 26.6 9.0 228.0 31.8 1.6 2.9 H3-5 "H3.5, H3F3C" ENSG00000188375 "H3.5 histone" Q6NXT2 12 31791185-31792298 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 21.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 83.8;Endothelial cells: 16.8;Fibroblasts: 23.8;Smooth muscle cells: 31.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 73.0" "Cell line enhanced" "Detected in some" "SH-SY5Y: 2.3" HPA042570 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA042570: AB_2678056" "unprognostic (2.82e-1)" "unprognostic (2.80e-4)" "unprognostic (2.60e-2)" "unprognostic (9.21e-2)" "unprognostic (3.77e-2)" "unprognostic (2.89e-2)" "unprognostic (2.92e-1)" "unprognostic (1.45e-1)" "unprognostic (7.56e-2)" "unprognostic (2.39e-1)" "unprognostic (4.06e-2)" "unprognostic (3.53e-2)" "unprognostic (2.73e-3)" "unprognostic (4.02e-2)" "unprognostic (2.99e-2)" "unprognostic (2.80e-2)" "unprognostic (3.86e-2)" 0.5 0.3 0.1 1.0 0.1 3.1 0.5 0.1 0.5 0.6 0.1 0.3 0.5 0.5 0.2 0.6 0.6 0.1 0.3 0.1 0.1 0.3 0.3 0.5 0.4 0.2 0.1 1.0 0.5 0.1 0.3 0.4 0.2 0.3 0.0 0.7 0.5 0.0 0.4 1.0 0.9 0.0 0.1 1.4 0.6 21.8 0.1 0.0 0.4 0.0 0.7 0.4 0.5 0.2 1.6 0.3 0.7 0.3 0.1 0.0 0.5 0.2 0.1 0.4 0.1 0.5 0.6 0.2 0.6 0.0 0.3 0.5 0.0 0.0 0.1 0.4 0.0 0.0 0.5 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.2 0.6 0.0 0.0 1.2 1.6 0.3 0.1 0.0 0.8 0.3 1.0 0.1 0.2 1.2 2.3 0.0 0.9 2.0 0.2 0.5 1.5 0.1 0.8 1.5 0.5 2.0 1.1 0.4 0.6 0.7 0.7 0.7 36.7 14.5 41.6 10.2 15.5 9.1 16.0 10.3 10.1 13.2 13.2 10.9 10.4 73.0 15.0 14.0 12.7 14.0 40.9 0.1 0.1 0.1 0.5 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.8 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 2.7 23.8 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.8 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 HEATR5A "C14orf125, DKFZP434I1735" ENSG00000129493 "HEAT repeat containing 5A" Q86XA9 14 31291788-31420550 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 67.8;Oligodendrocytes: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 120.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 120.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049539 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA049539: AB_2680809" "unprognostic (2.63e-1)" "unprognostic (2.24e-1)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (5.47e-3)" "unprognostic (3.97e-2)" "unprognostic (9.37e-2)" "unprognostic (8.02e-2)" "unprognostic (1.70e-1)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "prognostic favorable (1.11e-6)" "unprognostic (1.00e-1)" "unprognostic (5.93e-2)" "unprognostic (2.83e-2)" "unprognostic (6.00e-2)" 8.6 11.1 8.9 8.9 12.5 7.0 8.0 11.0 8.8 9.6 9.7 14.1 10.3 7.3 5.8 10.0 8.9 7.4 16.3 8.2 12.9 10.2 8.7 8.9 5.7 13.8 11.6 6.2 4.8 9.1 7.5 12.1 15.5 5.8 11.4 7.4 8.0 5.7 12.1 4.2 12.0 10.3 10.1 8.0 7.5 8.2 10.5 3.5 7.6 20.3 6.7 10.9 6.6 18.5 28.3 43.3 12.2 15.7 29.0 27.3 25.3 33.6 28.3 18.0 18.3 17.4 21.1 15.1 31.4 50.7 10.8 18.6 23.2 10.3 25.5 11.5 21.4 11.4 56.5 73.8 16.9 21.9 15.8 12.8 5.5 15.4 14.6 14.1 22.8 6.9 23.4 15.2 21.0 25.2 8.2 9.4 9.3 17.8 25.2 4.7 24.1 8.6 11.9 17.5 5.1 15.3 77.2 35.3 78.4 17.0 20.0 6.2 35.4 13.1 19.6 22.5 13.6 14.9 42.3 23.8 3.9 12.0 19.5 120.4 11.8 47.3 2.7 11.7 1.6 4.7 1.9 2.4 8.2 3.6 1.6 2.9 38.4 3.7 18.1 3.7 2.0 4.6 8.9 12.5 11.0 8.8 8.2 12.9 13.8 11.6 15.5 10.1 10.5 18.5 7.8 28.9 20.2 58.4 7.5 5.9 2.4 6.3 5.2 12.1 9.9 5.5 17.0 5.7 15.5 18.4 14.6 13.1 2.7 33.5 1.9 11.7 3.5 16.3 9.0 8.7 6.7 2.5 27.1 11.7 10.8 13.1 9.7 7.4 11.4 6.9 10.4 14.8 10.6 1.7 38.8 13.5 10.2 14.8 10.8 1.3 12.2 13.6 10.6 42.2 15.1 19.2 1.0 67.8 96.6 17.6 22.4 11.7 10.1 6.3 17.3 8.9 21.8 9.3 0.0 18.1 9.6 21.7 13.2 10.0 7.2 18.1 5.9 11.4 13.1 4.9 HES1 "bHLHb39, FLJ20408, HES-1, HRY" ENSG00000114315 "Hes family bHLH transcription factor 1" Q14469 3 194136148-194138732 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 850.6;Muller glia cells: 1146.0;Paneth cells: 1137.2;Undifferentiated cells: 882.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "eosinophil: 15.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 15.6" "Cell line enhanced" "Detected in many" "hTCEpi: 94.1;OE19: 95.8;SK-BR-3: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066929 Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA066929: AB_2732753" "unprognostic (1.79e-2)" "unprognostic (2.41e-1)" "unprognostic (1.79e-2)" "unprognostic (4.44e-2)" "unprognostic (1.00e-1)" "unprognostic (1.46e-1)" "unprognostic (3.01e-2)" "unprognostic (1.05e-1)" "unprognostic (4.64e-1)" "unprognostic (2.62e-2)" "unprognostic (2.04e-2)" "unprognostic (1.40e-2)" "unprognostic (1.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.74e-1)" "unprognostic (1.85e-1)" "prognostic favorable (2.04e-5)" 64.2 32.2 13.6 7.9 14.9 0.9 87.0 12.5 15.0 66.0 11.8 44.1 31.2 22.5 9.0 127.8 22.4 17.7 65.6 14.7 16.8 87.3 68.7 47.1 7.0 15.3 17.4 25.3 34.8 22.6 42.7 27.5 13.5 90.1 35.7 66.5 79.9 31.5 69.9 184.5 23.9 9.8 13.5 23.4 42.1 12.8 14.5 11.9 93.2 22.4 11.8 59.8 136.6 11.6 9.3 2.6 20.8 27.1 6.1 0.0 5.2 4.3 12.2 0.9 0.5 36.4 26.1 1.3 74.6 1.6 12.6 51.4 3.9 24.2 0.3 7.7 44.0 33.1 3.5 9.4 0.1 0.2 30.1 2.2 94.1 0.8 10.9 14.3 28.6 1.7 16.1 1.2 0.0 43.9 47.5 45.7 19.4 95.8 17.8 0.1 1.5 1.0 28.0 71.2 1.2 1.6 21.0 78.9 38.9 23.6 22.2 2.6 22.3 2.3 21.8 0.3 31.3 0.2 0.1 0.2 1.6 0.1 43.7 0.0 0.0 15.6 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 13.6 14.9 12.5 15.0 14.7 16.8 15.3 17.4 13.5 13.5 14.5 11.6 684.0 25.6 96.0 70.2 54.2 122.9 498.5 736.7 159.4 15.9 352.0 164.1 128.8 517.6 355.1 196.8 16.7 41.1 4.7 696.8 189.8 268.9 2.2 231.9 37.6 401.8 160.1 19.2 1.2 199.1 6.0 274.1 105.0 257.4 303.4 16.1 850.6 163.1 24.4 10.1 0.4 579.7 213.6 95.3 76.2 8.7 58.7 74.6 80.0 5.6 22.8 1146.0 0.0 4.5 0.1 227.1 1137.2 18.8 5.0 231.1 297.5 126.6 190.2 54.9 164.3 76.8 291.7 1.2 13.2 367.8 296.5 209.2 24.1 31.4 882.7 358.1 HEXA ENSG00000213614 "Hexosaminidase subunit alpha" P06865 15 72340924-72376420 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 234.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018082, HPA054583" Supported Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 20000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles Cytosol "HPA018082: , HPA054583: AB_2682531" "unprognostic (1.51e-2)" "unprognostic (1.73e-2)" "unprognostic (3.41e-1)" "prognostic favorable (5.63e-8)" "unprognostic (6.58e-2)" "unprognostic (1.32e-2)" "unprognostic (1.34e-2)" "unprognostic (2.82e-2)" "unprognostic (3.75e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (9.98e-2)" "unprognostic (3.98e-1)" "unprognostic (7.05e-3)" "unprognostic (3.02e-2)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" 49.8 56.1 18.3 37.6 21.1 110.0 58.5 20.4 21.6 73.8 28.5 55.1 49.8 42.6 164.6 24.8 47.8 76.7 54.3 19.9 20.1 90.1 79.4 84.2 54.2 23.0 21.3 39.3 30.6 54.0 26.3 102.0 24.6 45.3 67.0 32.1 45.0 53.3 22.1 21.8 41.2 59.5 21.7 54.7 45.1 35.6 27.0 38.1 76.5 33.2 42.4 71.6 19.7 29.9 39.8 66.4 27.8 53.8 223.6 253.1 39.7 54.8 274.1 115.3 182.8 34.6 282.7 32.9 50.9 110.0 59.9 77.1 74.5 34.6 72.5 26.5 30.0 41.4 60.4 60.9 172.9 99.9 113.1 216.7 101.3 50.4 89.3 210.3 107.4 48.4 65.1 197.6 156.0 33.9 21.7 50.0 16.0 128.9 0.3 22.3 60.6 75.3 129.1 61.6 23.8 26.4 136.5 126.6 307.3 56.1 23.4 123.9 54.1 171.9 70.7 160.1 59.3 104.7 151.8 33.4 62.1 130.4 85.3 24.2 84.6 60.1 43.8 35.7 38.7 41.1 28.8 38.9 98.0 38.0 22.5 33.2 8.1 51.3 13.3 37.3 28.2 63.0 18.3 21.1 20.4 21.6 19.9 20.1 23.0 21.3 24.6 21.7 27.0 29.9 68.9 64.1 62.4 19.9 46.3 22.2 33.3 94.3 19.4 42.4 28.6 30.4 26.9 30.0 68.0 66.2 106.3 150.2 54.2 36.6 60.7 88.3 20.6 27.2 30.2 50.8 47.2 19.1 22.7 38.0 68.0 78.7 42.8 40.6 29.9 49.9 43.5 42.9 234.3 26.9 24.7 46.3 81.4 92.8 75.0 13.7 74.3 118.1 94.3 24.4 60.3 38.4 82.4 20.6 26.7 39.1 74.6 44.8 37.7 33.0 68.5 66.7 37.5 56.9 46.0 24.5 31.7 24.3 32.3 13.5 15.6 157.6 36.7 45.2 50.6 27.5 HINT3 "FLJ33126, HINT4" ENSG00000111911 "Histidine triad nucleotide binding protein 3" Q9NQE9 6 125956770-125980244 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 112.8" "Cell type enhanced" "Detected in all" "Early spermatids: 352.2;Spermatocytes: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027914 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli, Mitochondria" Cytosol "HPA027914: AB_10602424" "prognostic unfavorable (4.99e-4)" "unprognostic (4.75e-3)" "unprognostic (3.75e-2)" "unprognostic (1.29e-1)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (1.74e-1)" "unprognostic (4.88e-3)" "unprognostic (3.82e-1)" "unprognostic (1.27e-1)" "unprognostic (2.18e-2)" "unprognostic (1.05e-1)" "prognostic favorable (1.05e-6)" "unprognostic (4.09e-2)" "unprognostic (4.76e-2)" "unprognostic (9.56e-2)" "unprognostic (1.64e-1)" 18.1 23.4 31.2 12.6 33.9 12.3 23.0 31.0 43.3 18.3 22.8 19.6 15.7 16.6 17.8 22.3 16.4 16.2 28.4 29.4 31.4 22.2 28.3 21.0 11.3 33.9 32.1 14.7 19.3 30.6 14.4 14.5 33.8 29.7 17.6 15.3 25.5 22.4 112.8 17.5 16.0 17.3 36.6 10.5 24.8 12.3 32.5 13.6 23.5 84.6 11.4 18.4 10.8 38.0 13.2 10.3 14.1 29.5 5.5 14.8 17.5 14.1 20.2 10.6 11.0 25.6 7.2 28.4 25.5 9.4 23.7 19.5 18.2 11.9 12.3 27.4 23.5 12.0 15.1 21.6 25.4 19.2 19.6 11.8 25.9 10.7 27.0 27.3 16.1 21.0 38.3 18.7 10.6 20.1 15.5 13.7 4.8 27.1 9.9 12.8 9.7 9.7 21.8 24.0 28.2 17.4 12.9 18.0 67.8 10.2 18.4 28.9 11.4 7.2 10.1 34.8 20.3 27.1 33.3 18.2 20.4 18.1 9.5 12.5 9.3 8.9 4.4 5.9 4.6 7.0 5.9 4.8 7.7 6.3 6.0 5.3 11.2 5.9 8.6 4.3 6.3 5.3 31.2 33.9 31.0 43.3 29.4 31.4 33.9 32.1 33.8 36.6 32.5 38.0 11.7 80.1 61.2 11.8 16.7 18.1 10.2 22.1 24.5 21.8 26.5 18.4 38.7 10.0 29.8 16.5 8.4 19.2 13.4 17.2 33.2 29.3 352.2 23.6 11.5 12.3 16.3 6.9 27.0 20.2 6.4 13.7 19.4 25.8 9.5 15.2 10.4 17.5 27.2 6.7 29.8 25.1 20.3 15.3 14.6 78.3 9.9 19.3 21.4 5.6 17.3 43.4 11.3 21.6 40.0 21.4 28.7 17.3 8.1 20.9 15.3 28.0 25.7 25.4 6.6 18.3 15.1 110.7 40.2 21.5 17.3 26.4 11.3 14.6 18.5 19.9 HMG20A "FLJ10739, HMGX1, HMGXB1" ENSG00000140382 "High mobility group 20A" Q9NP66 15 77420412-77485607 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008126 Supported Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA008126: AB_1079072" "unprognostic (2.04e-1)" "unprognostic (6.87e-2)" "unprognostic (2.88e-1)" "unprognostic (1.11e-1)" "unprognostic (2.56e-1)" "unprognostic (1.70e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-1)" "unprognostic (1.14e-1)" "unprognostic (4.61e-2)" "unprognostic (1.75e-1)" "unprognostic (9.74e-3)" "unprognostic (3.40e-1)" "unprognostic (1.58e-1)" "unprognostic (1.50e-1)" "unprognostic (2.65e-1)" 12.2 18.2 14.5 15.9 14.2 10.2 14.2 15.1 17.6 15.2 7.8 15.4 12.4 20.3 13.6 13.4 13.2 15.5 25.1 14.4 14.8 14.0 24.9 15.7 25.2 11.5 12.9 22.2 13.0 18.1 9.7 21.8 11.3 11.6 17.0 26.0 13.5 13.9 27.2 13.4 14.2 15.7 12.0 35.8 13.6 21.3 15.0 31.6 15.0 26.4 22.1 14.4 10.8 16.6 17.8 29.8 53.8 38.4 22.4 28.4 21.6 23.2 34.6 27.2 29.5 18.6 26.7 30.2 26.4 27.0 21.0 23.8 76.6 29.3 27.6 27.1 38.4 62.3 26.6 24.5 33.4 46.1 35.7 31.9 20.9 24.2 26.8 36.3 54.9 38.9 47.8 24.6 25.1 14.1 36.8 32.1 39.0 15.8 14.2 48.0 52.1 34.2 31.1 30.7 21.1 45.3 37.5 22.6 70.6 51.2 22.3 48.3 33.8 32.3 28.4 15.2 28.4 33.2 75.7 59.9 24.1 66.3 38.4 9.2 20.8 16.9 29.1 21.2 34.4 31.3 22.9 27.3 27.8 27.3 30.8 27.3 3.4 49.2 26.1 21.1 23.7 24.9 14.5 14.2 15.1 17.6 14.4 14.8 11.5 12.9 11.3 12.0 15.0 16.6 14.6 12.8 11.5 39.2 18.1 8.8 5.3 10.0 13.6 20.6 13.0 12.3 47.2 14.3 10.7 11.0 25.0 13.7 12.9 12.2 5.9 9.9 25.9 10.4 21.1 16.8 18.0 15.4 60.1 8.0 9.5 17.2 13.7 10.0 12.7 16.5 22.9 32.4 16.6 38.7 56.9 15.6 6.1 28.6 11.9 79.5 12.8 13.0 14.2 29.0 22.1 14.3 19.6 64.3 71.1 9.0 10.8 13.9 13.3 6.0 8.4 10.6 4.9 20.6 19.7 13.4 13.2 28.2 17.0 11.3 7.4 13.8 16.4 25.5 13.8 5.5 HMG20B "BRAF25, BRAF35, HMGX2, HMGXB2, SMARCE1r, SOXL" ENSG00000064961 "High mobility group 20B" Q9P0W2 19 3572777-3579088 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 265.7;Melanocytes: 229.5;Syncytiotrophoblasts: 303.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 411.1;WM-115: 405.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050220, HPA053157, HPA069832" Approved Enhanced Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA050220: AB_2681056, HPA053157: AB_2682061, HPA069832: AB_2686210" "unprognostic (2.97e-1)" "unprognostic (1.84e-2)" "unprognostic (2.57e-1)" "prognostic favorable (1.72e-7)" "unprognostic (2.18e-2)" "unprognostic (1.77e-2)" "unprognostic (1.12e-1)" "unprognostic (2.97e-1)" "unprognostic (1.66e-1)" "unprognostic (4.62e-2)" "unprognostic (3.19e-2)" "unprognostic (1.43e-2)" "unprognostic (1.71e-1)" "unprognostic (1.91e-3)" "unprognostic (2.78e-2)" "unprognostic (1.84e-1)" "prognostic favorable (2.89e-5)" 50.4 41.4 27.3 18.2 29.3 30.1 49.9 29.1 33.7 50.9 29.4 59.0 28.1 54.5 15.6 48.1 44.7 16.8 36.8 26.0 27.5 56.0 54.4 38.3 20.1 32.6 28.4 38.0 38.1 30.3 18.1 22.7 31.8 68.9 17.2 8.8 49.9 25.6 25.9 58.3 47.6 19.9 29.6 39.2 54.2 36.0 30.3 48.2 39.3 12.0 15.9 49.0 43.8 34.1 93.1 39.0 34.6 83.0 42.2 38.1 64.1 58.7 42.4 52.6 40.0 14.1 33.5 50.5 53.7 42.6 47.5 44.4 20.3 40.0 31.3 45.1 46.6 24.8 132.2 37.7 27.2 33.9 117.5 32.5 47.0 30.2 20.0 53.4 53.4 44.8 42.0 81.9 35.0 126.3 64.7 62.0 39.7 78.5 78.4 42.3 60.4 69.5 39.0 58.4 21.7 66.0 81.7 141.3 411.1 32.4 106.8 90.5 77.4 27.7 62.1 99.3 50.8 76.4 43.0 36.2 72.0 85.6 405.1 44.9 68.1 66.2 40.1 70.1 35.8 35.2 34.1 43.6 66.1 30.2 36.3 35.3 37.9 59.5 77.0 59.5 41.4 51.8 27.3 29.3 29.1 33.7 26.0 27.5 32.6 28.4 31.8 29.6 30.3 34.1 50.1 28.9 19.3 9.8 27.9 70.5 52.1 67.4 47.8 3.4 75.0 70.9 8.7 28.6 40.0 18.4 10.4 122.9 34.1 50.0 92.0 65.0 26.7 39.7 41.4 42.5 66.8 24.4 0.7 45.5 265.7 35.4 32.6 44.4 37.5 58.1 38.6 20.9 81.9 8.4 0.7 170.8 57.0 29.6 93.4 49.6 37.3 47.1 229.5 3.7 86.2 41.2 42.2 0.5 11.7 58.6 68.5 44.8 34.9 62.8 74.7 76.2 29.5 18.7 32.9 22.4 53.4 39.9 17.4 53.0 79.8 303.7 30.8 49.6 68.7 62.9 HSBP1L1 "FLJ10967, MGC189743" ENSG00000226742 "Heat shock factor binding protein 1 like 1" C9JCN9 18 79964582-79970822 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "granulocytes: 31.9;T-cells: 26.0" "Cell line enhanced" "Detected in many" "HHSteC: 162.8;SK-MEL-30: 100.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048273 Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA048273: AB_2680337" "unprognostic (2.08e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-2)" "unprognostic (5.85e-2)" "unprognostic (2.71e-2)" "unprognostic (3.70e-2)" "unprognostic (8.15e-3)" "unprognostic (8.86e-2)" "unprognostic (1.47e-1)" "unprognostic (1.16e-1)" "unprognostic (2.53e-3)" "unprognostic (7.41e-2)" "unprognostic (4.70e-2)" "unprognostic (1.67e-1)" "unprognostic (2.12e-1)" "unprognostic (8.28e-2)" "unprognostic (1.76e-2)" 9.6 17.4 18.4 2.9 17.8 2.9 9.6 19.9 26.4 10.0 23.4 16.0 6.7 7.6 11.1 17.4 8.7 5.7 6.7 17.2 18.1 18.6 29.7 10.7 4.2 19.1 18.5 6.6 20.4 19.7 6.7 9.9 19.6 10.2 13.1 14.8 12.8 7.6 12.5 16.0 6.5 5.7 18.1 5.2 10.1 0.8 20.3 4.3 8.9 10.6 4.9 6.2 10.6 17.2 32.2 8.6 0.3 0.5 4.6 15.4 12.7 14.3 32.2 14.8 13.0 16.5 21.7 0.0 3.6 18.8 0.2 18.3 28.5 18.9 7.0 30.6 6.7 0.0 8.8 9.6 162.8 0.0 0.0 18.0 49.6 1.7 10.8 31.5 0.3 4.8 0.0 0.0 0.7 26.8 0.1 0.0 0.0 17.6 30.1 0.3 0.0 0.0 53.7 7.6 0.5 1.8 15.2 20.9 100.2 1.4 11.9 7.6 0.0 0.1 0.0 0.4 0.1 0.0 16.7 0.0 0.2 8.9 0.6 31.9 6.8 8.6 5.8 4.4 6.9 2.2 10.1 6.2 2.8 2.5 26.0 14.0 0.4 5.2 1.6 3.3 4.9 6.2 18.4 17.8 19.9 26.4 17.2 18.1 19.1 18.5 19.6 18.1 20.3 17.2 36.4 54.5 34.5 12.1 5.0 39.8 66.0 135.5 67.2 12.0 89.8 93.6 12.4 48.6 109.2 49.7 22.9 126.6 9.6 119.8 68.4 63.8 1.3 47.2 13.2 23.0 11.5 11.4 5.7 62.1 67.1 16.0 31.6 59.4 19.0 37.2 30.0 122.5 44.7 20.2 11.0 81.3 71.2 20.5 18.0 1.3 19.9 16.0 39.2 6.5 4.0 33.2 6.2 1.0 3.1 137.3 99.6 24.5 2.3 80.2 70.6 80.6 80.3 33.0 0.0 6.3 15.9 1.3 1.3 46.8 57.8 117.4 12.2 34.5 99.6 104.4 HSD3B2 SDR11E2 ENSG00000203859 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2" P26439 1 119414931-119423035 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis "Isomerase, Multifunctional enzyme, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "adrenal gland: 2174.8" "Group enriched" "Detected in some" 4 "Granulosa cells: 40.6;Proximal enterocytes: 38.8;Theca cells: 68.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.4" "HPA043261, HPA043264, HPA044028" Supported Uncertain "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (3.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.80e-1)" "unprognostic (2.72e-2)" "unprognostic (8.87e-2)" "unprognostic (3.91e-2)" "unprognostic (3.43e-2)" "unprognostic (1.94e-1)" "unprognostic (6.51e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" 0.2 2174.8 0.3 2.1 0.8 0.0 0.1 0.0 0.7 0.2 0.0 7.7 0.0 0.2 0.0 0.2 0.4 0.0 0.3 0.2 0.0 0.9 1.0 0.5 0.0 0.0 0.0 0.9 0.5 0.0 0.1 3.6 0.1 0.4 1.0 0.0 1.0 0.0 0.1 0.2 38.7 0.1 0.0 0.2 0.3 2.9 0.2 0.5 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 1.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 3.5 0.0 0.0 0.0 40.6 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.0 38.8 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 68.9 1.7 0.0 HTR2B "5-HT(2B), 5-HT2B" ENSG00000135914 "5-hydroxytryptamine receptor 2B" P41595 2 231108230-231125042 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 17.4;cervix: 21.5;endometrium 1: 18.8;smooth muscle: 16.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Endometrial stromal cells: 17.7;Endothelial cells: 4.1;Hepatic stellate cells: 5.7;Microglial cells: 4.7;monocytes: 6.2;Peritubular cells: 5.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "basophil: 1.8;T-reg: 1.0" "Group enriched" "Detected in many" 15 "granulocytes: 1.8;T-cells: 1.0" "Group enriched" "Detected in some" 4 "HHSteC: 8.7;HSkMC: 16.5;SK-MEL-30: 32.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012867, HPA063658" Enhanced Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "HPA012867: AB_1856710, HPA063658: AB_2685079" "unprognostic (1.86e-1)" "unprognostic (3.55e-2)" "unprognostic (1.20e-3)" "unprognostic (1.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.53e-2)" "unprognostic (1.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.15e-4)" "unprognostic (3.59e-1)" "unprognostic (2.17e-2)" "unprognostic (1.42e-3)" "unprognostic (7.44e-4)" "unprognostic (1.81e-1)" "unprognostic (1.17e-1)" "unprognostic (1.14e-2)" 0.9 17.4 0.4 1.5 0.4 1.2 0.8 0.9 0.6 21.5 1.2 9.0 1.5 18.8 11.8 0.7 2.4 1.2 4.7 0.4 0.6 3.4 3.6 0.9 1.0 0.5 0.4 0.8 0.2 0.6 0.3 4.1 0.5 0.3 2.1 0.2 0.5 1.4 0.1 0.1 4.8 16.8 0.2 0.4 4.5 0.4 0.4 1.2 3.2 0.3 0.8 2.2 0.8 0.6 0.2 0.3 0.0 0.1 0.5 4.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 8.7 0.1 0.3 16.5 0.0 0.0 0.0 0.0 3.2 1.4 0.1 0.0 0.0 0.2 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 32.7 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.4 0.9 0.6 0.4 0.6 0.5 0.4 0.5 0.2 0.4 0.6 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.0 0.2 0.0 4.2 0.1 0.1 0.0 0.0 0.0 0.2 1.5 17.7 4.1 0.0 0.0 0.7 0.7 0.1 0.8 0.0 3.4 0.0 0.1 5.7 1.5 3.4 1.7 0.9 0.0 0.0 0.8 0.0 0.2 0.6 2.2 0.0 4.7 6.2 0.0 1.0 0.5 0.6 0.2 0.0 5.3 0.0 0.0 0.0 0.0 2.0 0.7 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.3 0.2 0.3 0.0 0.2 IER5 ENSG00000162783 "Immediate early response 5" Q5VY09 1 181088700-181092900 "Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 282.8;Macrophages: 276.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029894 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Nucleoli "HPA029894: AB_10601433" "unprognostic (1.18e-1)" "unprognostic (1.31e-1)" "unprognostic (2.55e-1)" "prognostic favorable (2.42e-7)" "unprognostic (1.00e-2)" "unprognostic (1.47e-1)" "unprognostic (2.63e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (2.81e-3)" "unprognostic (8.37e-2)" "unprognostic (1.46e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (1.26e-2)" "unprognostic (2.54e-1)" "unprognostic (1.11e-1)" "unprognostic (1.09e-1)" 12.8 6.3 9.5 11.2 10.2 49.5 8.4 10.1 19.3 10.2 11.2 10.6 5.6 14.8 2.5 26.5 15.2 6.1 27.8 10.7 9.7 5.8 6.7 23.2 9.4 10.0 9.2 3.3 5.2 1.8 5.2 11.0 9.1 5.6 5.6 1.1 6.8 3.7 33.4 22.1 13.3 8.3 9.8 32.7 9.0 5.4 10.3 8.7 5.0 16.5 10.8 10.9 13.3 12.8 25.3 21.8 11.7 10.3 15.9 21.9 31.3 43.6 45.9 24.1 21.4 6.1 13.8 8.3 18.9 16.9 16.9 45.5 3.8 29.7 15.6 47.6 18.7 7.4 11.5 4.1 24.9 8.6 23.1 15.7 29.5 28.0 18.7 18.3 16.6 6.9 31.0 36.5 43.3 11.5 8.6 13.8 12.2 9.5 10.8 9.8 20.4 31.6 8.8 13.7 16.9 18.2 22.1 21.3 51.7 14.2 17.0 7.5 25.3 17.3 30.5 19.9 26.8 23.9 9.1 6.5 13.5 9.0 4.9 3.6 1.4 2.7 1.0 5.5 1.2 4.0 0.8 1.4 1.1 3.0 0.1 0.5 1.2 1.1 5.3 0.2 1.3 0.7 9.5 10.2 10.1 19.3 10.7 9.7 10.0 9.2 9.1 9.8 10.3 12.8 156.4 22.4 66.7 3.6 124.8 69.8 163.7 24.2 53.5 24.2 198.1 197.7 110.9 21.5 25.9 9.2 37.5 10.9 131.1 94.2 0.0 10.6 5.1 66.7 83.0 87.2 56.4 32.0 8.7 6.9 56.4 74.7 50.0 67.3 36.1 35.0 41.4 5.6 50.9 8.4 2.8 110.6 6.1 149.5 282.8 11.9 12.2 276.4 46.2 11.2 56.1 17.8 17.5 0.5 1.3 21.9 54.8 9.4 61.5 94.9 35.0 1.5 27.4 21.3 0.0 177.9 102.8 3.6 5.4 115.9 59.7 34.2 151.3 15.5 62.0 146.8 IGHMBP2 "CATF1, CMT2S, HCSA, HMN6, SMARD1, SMUBP2, ZFAND7" ENSG00000132740 "Immunoglobulin mu DNA binding protein 2" P38935 11 68903863-68940602 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase, Ribonucleoprotein, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 94.6;Late spermatids: 46.9;Spermatocytes: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004092, HPA060994" Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA004092: , HPA060994: AB_2684406" "unprognostic (1.17e-1)" "unprognostic (1.04e-1)" "unprognostic (7.17e-2)" "unprognostic (3.96e-1)" "unprognostic (1.54e-1)" "unprognostic (1.69e-1)" "unprognostic (3.59e-3)" "unprognostic (4.31e-2)" "unprognostic (3.81e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.89e-4)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.29e-8)" "unprognostic (1.69e-1)" "unprognostic (3.73e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" 5.2 4.0 1.2 2.5 1.3 6.0 5.4 0.7 1.7 7.0 0.1 11.8 1.5 7.8 0.6 5.5 6.7 1.7 5.2 1.6 1.2 4.4 6.3 5.1 3.3 0.8 0.4 6.1 5.2 2.8 4.0 2.0 0.7 6.3 1.5 1.4 6.4 3.1 8.5 7.7 6.3 2.6 0.5 5.7 6.2 15.4 0.6 4.3 4.9 3.8 1.7 6.3 5.8 1.1 5.1 7.3 4.0 7.4 3.6 3.1 5.2 5.8 3.9 7.8 4.6 14.5 7.0 7.3 9.7 3.3 6.9 8.0 5.8 4.9 1.8 8.3 6.2 6.6 9.6 5.6 5.5 6.5 7.4 1.8 4.9 9.2 4.6 4.5 4.6 11.1 10.6 4.6 2.3 5.1 11.1 8.9 2.3 7.9 10.3 9.4 5.7 7.6 3.3 5.9 8.6 5.4 7.4 6.1 16.6 3.0 9.3 6.0 6.6 5.3 3.8 7.7 6.6 6.0 6.3 6.9 5.3 6.1 5.1 0.0 2.0 0.8 1.5 1.8 1.3 1.0 0.9 1.0 1.8 0.6 0.5 0.7 0.6 0.1 1.1 0.3 0.6 1.3 1.2 1.3 0.7 1.7 1.6 1.2 0.8 0.4 0.7 0.5 0.6 1.1 6.6 6.4 7.7 7.5 5.7 5.7 3.8 3.5 6.2 9.1 5.6 3.8 6.3 8.6 6.1 1.8 20.9 4.9 10.2 6.0 1.9 5.1 94.6 7.0 8.1 6.4 3.0 9.3 7.4 5.1 4.4 5.5 6.1 14.0 7.0 10.7 3.3 6.1 5.8 11.8 6.4 4.1 2.0 3.5 4.3 46.9 7.8 7.2 1.8 5.6 7.3 6.6 9.2 6.0 5.2 6.5 8.4 7.2 5.8 7.5 3.9 2.9 3.8 10.1 0.0 5.1 10.1 51.6 7.1 5.3 6.7 6.7 8.0 4.6 7.1 6.3 IGSF11 "BT-IgSF, CT119, Igsf13, MGC35227, VSIG3" ENSG00000144847 "Immunoglobulin superfamily member 11" Q5DX21 3 118900557-119146068 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Growth regulation" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 46.3;ovary: 16.2;retina: 50.6;testis: 35.7" "Cell type enhanced" "Detected in many" "Astrocytes: 133.9;Early spermatids: 257.9;Inhibitory neurons: 139.1;Late spermatids: 334.0;Oligodendrocytes: 283.2" "Group enriched" "Detected in many" 9 "glioma: 9.2;melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 8.0;HEL: 5.9;SK-MEL-30: 35.1;U-266/70: 11.9;U-266/84: 15.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046377 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "Nucleoplasm, Cytosol" "HPA046377: AB_10966195" "unprognostic (2.05e-1)" "unprognostic (1.29e-1)" "unprognostic (1.62e-1)" "unprognostic (1.88e-1)" "unprognostic (1.17e-2)" "unprognostic (1.89e-3)" "unprognostic (2.51e-2)" "unprognostic (3.56e-2)" "unprognostic (3.91e-1)" "unprognostic (1.44e-1)" "unprognostic (2.20e-1)" "unprognostic (8.70e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-4)" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (7.57e-2)" 0.3 7.8 19.5 0.4 34.0 0.0 0.2 26.9 22.2 0.8 1.5 4.1 0.2 0.5 1.1 1.2 0.6 0.8 2.2 19.3 18.6 8.2 0.1 0.1 0.1 30.5 28.0 16.2 3.7 1.3 1.7 0.1 29.9 0.7 0.8 50.6 0.6 0.8 3.9 1.5 0.9 0.5 23.3 0.1 1.6 35.7 25.6 0.3 3.4 5.0 0.2 0.6 0.8 46.3 0.0 8.0 0.2 0.1 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 2.7 0.0 0.0 0.0 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.7 0.6 0.0 0.1 35.1 2.1 0.7 0.1 0.0 0.0 1.4 0.0 0.1 11.9 15.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 34.0 26.9 22.2 19.3 18.6 30.5 28.0 29.9 23.3 25.6 46.3 0.1 0.0 0.0 133.9 0.6 0.4 0.1 0.3 2.8 9.1 0.3 0.1 1.3 0.0 0.5 0.0 75.0 0.2 0.1 0.0 0.0 0.9 257.9 4.2 0.8 0.3 0.0 0.0 77.8 0.7 0.0 2.0 0.0 7.2 0.0 26.8 0.0 0.0 0.0 16.8 139.1 0.0 6.1 0.0 0.4 334.0 3.7 0.4 3.6 4.7 0.0 22.3 0.0 43.2 283.2 0.2 0.0 1.9 0.2 0.1 0.0 5.9 0.4 25.7 0.0 0.8 0.9 22.4 6.0 0.7 0.0 0.1 0.2 6.8 0.0 0.4 IGSF8 "CD316, CD81P3, EWI2, PGRL" ENSG00000162729 "Immunoglobulin superfamily member 8" Q969P0 1 160091340-160098943 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 155.3" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011917, HPA075970" Approved Supported Vesicles NA NA 280000 "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA011917: AB_1851536, HPA075970: " "unprognostic (4.08e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.20e-1)" "unprognostic (1.71e-1)" "unprognostic (1.01e-3)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.31e-1)" "unprognostic (2.60e-2)" "unprognostic (2.35e-1)" "unprognostic (3.74e-3)" "unprognostic (1.75e-3)" 21.9 19.1 97.9 14.0 119.0 3.7 26.7 91.7 130.7 25.7 39.9 31.7 26.5 19.8 22.7 22.3 28.2 12.3 29.0 106.0 82.4 35.5 53.9 23.6 16.8 109.3 97.8 37.5 31.8 15.8 30.7 11.2 99.9 26.4 10.4 14.3 30.1 18.2 12.4 50.3 28.5 7.0 98.6 24.2 27.5 33.4 94.7 13.6 28.6 7.1 8.9 20.3 25.0 155.3 26.8 15.7 20.1 51.3 11.6 7.3 42.9 12.9 16.8 26.9 25.0 17.9 17.9 39.0 47.1 18.8 23.4 50.3 8.2 18.9 3.8 47.3 15.0 5.1 17.3 31.2 19.2 13.5 41.7 9.0 37.7 17.5 5.6 19.0 5.6 42.0 7.0 21.8 6.3 25.4 33.8 31.3 42.4 55.6 24.8 19.1 10.3 28.7 24.7 27.4 8.5 36.6 14.8 47.4 177.6 17.5 33.7 17.3 5.8 11.8 25.4 21.5 10.6 59.6 71.2 17.7 41.6 5.3 31.6 0.1 5.2 2.4 22.0 7.2 19.5 19.6 18.0 25.6 5.8 22.7 23.4 25.7 1.4 9.2 4.7 9.9 26.9 11.3 97.9 119.0 91.7 130.7 106.0 82.4 109.3 97.8 99.9 98.6 94.7 155.3 12.2 9.6 3.3 18.3 21.1 43.7 30.2 43.1 26.2 55.6 28.0 29.2 3.3 17.2 16.7 38.6 10.4 32.8 15.1 36.1 5.9 34.2 3.8 12.0 7.2 7.8 19.9 7.4 65.3 12.4 219.7 22.4 6.6 26.4 10.2 12.2 13.2 28.8 14.9 65.6 43.8 24.7 44.7 4.3 16.2 1.1 16.8 8.5 42.7 9.4 51.5 75.7 10.3 9.0 107.2 20.6 39.5 15.8 20.0 22.0 47.6 15.8 6.0 11.8 6.6 39.8 15.3 4.0 6.6 21.0 62.4 69.4 19.5 13.6 32.6 26.0 IL12RB2 ENSG00000081985 "Interleukin 12 receptor subunit beta 2" Q99665 1 67307364-67398724 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.5;placenta: 7.0" "Cell type enhanced" "Detected in some" "dendritic cells: 8.4;Excitatory neurons: 22.5;Inhibitory neurons: 16.6;T-cells: 12.8" "Group enriched" "Detected in many" 4 "cervical cancer: 1.8;head and neck cancer: 2.5;melanoma: 5.6;renal cancer: 1.7" "Region enhanced" "Detected in many" "hippocampal formation: 4.5" "Immune cell enhanced" "Detected in many" "NK-cell: 21.3" "Group enriched" "Detected in many" 35 "NK-cells: 21.3;T-cells: 6.0" "Group enriched" "Detected in some" 9 "HMC-1: 4.6;SCLC-21H: 6.8;SK-MEL-30: 18.4;THP-1: 13.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "Low region specificity" "Detected in all" HPA024168 Uncertain Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA024168: AB_1851629" "unprognostic (1.32e-1)" "unprognostic (1.54e-3)" "unprognostic (2.09e-1)" "unprognostic (2.68e-2)" "unprognostic (2.82e-2)" "unprognostic (1.09e-3)" "unprognostic (2.37e-2)" "unprognostic (3.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.38e-2)" "unprognostic (1.39e-1)" "unprognostic (3.60e-2)" "unprognostic (1.08e-3)" "unprognostic (1.82e-1)" "unprognostic (4.69e-2)" "unprognostic (7.11e-3)" "unprognostic (1.90e-1)" 1.9 0.3 1.2 1.2 1.6 0.8 0.4 0.0 2.3 0.6 0.0 0.4 0.3 0.2 0.3 0.8 0.1 0.5 0.2 4.5 0.0 0.3 0.8 0.4 1.8 0.0 0.7 0.2 2.6 0.8 0.0 7.0 0.0 0.1 0.4 0.1 1.3 0.7 3.5 1.4 0.4 0.4 0.0 1.4 0.3 1.0 0.3 1.0 0.1 0.7 0.9 0.7 0.2 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 1.2 0.6 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.3 0.0 0.1 18.4 0.0 0.0 13.4 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 6.0 0.0 3.2 0.0 1.6 1.0 0.0 0.0 0.0 0.1 0.3 21.3 0.0 0.0 3.9 1.2 1.2 1.6 0.0 2.3 4.5 0.0 0.0 0.7 0.0 0.0 0.3 0.7 0.2 0.0 2.3 1.0 0.6 0.5 0.2 0.1 0.6 0.0 0.1 0.3 0.7 0.0 0.7 0.0 0.0 0.0 8.4 0.0 0.0 0.0 1.5 0.3 0.3 0.1 0.0 0.8 22.5 0.0 0.0 0.9 2.6 0.7 0.0 1.5 0.0 0.0 3.8 0.0 16.6 0.0 0.0 0.8 0.9 0.9 0.0 0.5 1.8 2.8 0.0 0.0 4.1 1.0 1.6 0.2 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.0 0.6 0.0 12.8 0.0 0.0 0.1 IL1RAP "C3orf13, IL-1RAcP, IL1R3" ENSG00000196083 "Interleukin 1 receptor accessory protein" Q9NPH3 3 190514051-190659750 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 225.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 109.2;Hepatocytes: 295.8;Oligodendrocyte precursor cells: 298.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "eosinophil: 23.8;neutrophil: 95.0" "Lineage enriched" "Detected in many" 15 "granulocytes: 95.0" "Cell line enriched" "Detected in many" 4 "SK-MEL-30: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035293 Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 350000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "HPA035293: AB_10671511" "unprognostic (6.48e-2)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (8.84e-3)" "unprognostic (2.35e-2)" "unprognostic (6.60e-2)" "unprognostic (2.62e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.16e-7)" "unprognostic (4.02e-3)" "unprognostic (9.06e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (6.29e-4)" 6.2 2.9 4.0 11.4 1.1 20.3 4.3 0.0 8.7 4.4 0.5 2.2 1.8 4.0 2.6 13.1 5.4 12.1 3.9 4.6 3.1 3.3 225.8 8.2 2.7 2.4 3.7 3.0 3.9 1.5 1.2 37.0 3.3 3.9 2.2 2.4 5.2 3.4 1.3 11.9 2.2 6.4 1.5 5.4 4.5 1.3 5.5 4.6 4.0 2.1 4.8 9.4 5.5 3.3 13.3 3.0 5.5 0.8 9.5 7.7 10.0 5.8 11.9 13.4 13.2 5.8 29.3 2.2 59.2 16.4 31.1 34.1 3.0 57.6 18.7 2.5 3.6 2.9 5.3 14.5 19.6 20.2 9.5 10.3 23.1 19.7 59.2 27.8 6.0 5.9 0.4 0.2 6.4 6.5 1.7 9.4 8.5 6.0 6.0 9.5 8.2 4.8 5.3 14.8 1.0 0.0 26.3 15.0 247.1 5.2 9.6 14.6 7.9 10.3 10.4 32.1 26.6 5.0 0.2 0.5 17.2 18.0 60.9 11.7 3.8 23.8 1.8 4.3 3.3 2.1 2.1 2.3 3.8 2.1 2.0 1.3 95.0 0.3 6.3 0.6 2.1 1.4 4.0 1.1 0.0 8.7 4.6 3.1 2.4 3.7 3.3 1.5 5.5 3.3 3.5 0.0 14.7 6.5 6.8 44.7 16.5 45.8 68.9 6.5 2.5 4.7 5.5 40.0 22.8 3.7 8.4 8.5 3.6 1.8 0.0 7.7 4.4 8.6 3.8 8.0 5.4 4.4 44.3 7.5 109.2 7.3 7.1 12.3 7.6 0.7 7.5 295.8 7.8 0.0 63.3 1.4 4.1 33.7 17.7 0.6 4.4 28.8 8.8 53.4 5.0 1.0 6.2 298.6 1.5 19.7 0.8 2.6 5.3 11.5 0.7 1.1 8.7 0.6 0.0 18.0 5.1 0.1 0.6 30.9 37.2 24.2 5.2 1.4 1.1 14.3 IMMP2L "IMMP2L-IT1, IMP2" ENSG00000184903 "Inner mitochondrial membrane peptidase subunit 2" Q96T52 7 110662644-111562517 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 247.8;Distal tubular cells: 160.4;Excitatory neurons: 365.4;Inhibitory neurons: 373.9;Microglial cells: 455.3;Oligodendrocyte precursor cells: 273.9;Oligodendrocytes: 233.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026711 Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA026711: AB_1851760" "unprognostic (2.55e-2)" "unprognostic (1.40e-2)" "unprognostic (4.29e-1)" "unprognostic (1.04e-1)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.89e-5)" "unprognostic (5.64e-3)" "unprognostic (1.00e-1)" "unprognostic (4.17e-1)" "unprognostic (5.68e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.89e-3)" "unprognostic (1.32e-1)" "unprognostic (6.65e-2)" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" 19.2 14.2 10.4 5.1 12.5 5.2 15.7 9.6 11.7 12.4 14.2 14.6 7.6 15.3 11.9 8.0 16.0 8.5 13.1 11.9 12.2 34.0 25.7 8.1 7.5 11.3 11.3 19.5 12.1 20.1 8.0 9.0 11.3 19.0 8.2 9.2 11.1 21.1 27.3 10.2 12.9 14.2 10.9 8.4 11.8 9.9 11.4 8.9 23.5 25.1 7.5 12.5 10.5 13.1 17.5 10.3 6.1 25.1 15.8 16.0 10.7 11.8 11.9 7.7 8.1 5.1 19.8 28.4 31.4 10.2 14.3 9.6 6.6 23.6 12.7 17.9 6.7 9.7 44.2 14.0 24.2 18.2 1.1 27.9 30.7 3.3 21.4 35.0 10.2 26.2 32.0 21.4 5.9 12.3 24.4 20.3 6.0 33.2 15.8 5.1 50.0 15.0 28.0 7.3 7.0 22.1 5.1 23.8 67.3 17.2 9.6 10.4 6.5 11.8 12.3 11.9 14.4 12.2 3.5 17.4 12.9 8.4 63.1 15.9 9.1 2.9 10.5 11.9 19.4 28.5 18.3 12.3 17.0 38.7 25.0 17.6 0.5 47.0 17.3 21.3 12.4 8.1 10.4 12.5 9.6 11.7 11.9 12.2 11.3 11.3 11.3 10.9 11.4 13.1 22.3 19.2 13.2 247.8 20.4 32.9 34.4 41.4 39.9 11.3 35.3 39.4 19.5 15.7 23.9 47.8 8.4 22.4 11.9 3.1 160.4 30.1 8.4 10.4 12.6 15.3 19.3 21.9 365.4 8.1 27.1 19.5 12.8 12.0 3.8 11.3 11.7 23.8 11.7 8.4 373.9 7.0 28.5 4.9 14.1 5.6 49.4 6.1 21.4 455.3 10.1 16.3 1.0 273.9 233.7 10.8 6.8 35.0 9.2 36.2 25.5 66.8 13.3 15.6 13.1 19.5 46.7 24.2 12.8 28.0 26.6 16.3 12.6 18.7 11.7 22.1 INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726042-119829147 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.3" "Cell type enhanced" "Detected in all" "Excitatory neurons: 79.5;Inhibitory neurons: 130.5;Late spermatids: 88.6;Oligodendrocytes: 70.5" "Cancer enhanced" "Detected in all" "testis cancer: 27.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 91.4;SK-MEL-30: 149.0;SuSa: 181.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042605 Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA042605: AB_10793886" "unprognostic (2.65e-2)" "unprognostic (3.23e-1)" "unprognostic (3.42e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-2)" "unprognostic (1.57e-3)" "unprognostic (2.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (6.46e-2)" "unprognostic (7.78e-2)" "unprognostic (1.02e-1)" "unprognostic (9.91e-2)" "unprognostic (2.96e-2)" "unprognostic (6.21e-2)" 9.9 16.8 53.8 9.9 49.4 4.7 7.6 45.3 63.9 15.7 10.1 15.5 4.6 15.4 22.8 9.3 8.3 6.9 5.9 50.6 135.3 10.5 3.2 9.1 10.7 71.2 57.3 12.3 6.7 7.4 57.1 10.9 75.0 10.9 8.0 32.9 10.8 10.0 11.0 13.7 9.5 13.2 50.3 7.5 8.6 14.8 62.7 7.0 10.5 3.8 13.0 9.2 12.5 55.2 13.5 8.2 91.4 14.3 6.9 10.6 8.5 18.4 9.3 8.4 8.4 12.0 15.2 8.3 7.6 19.7 10.6 14.4 7.9 9.8 11.9 6.0 10.3 6.5 3.9 11.0 13.5 4.4 19.0 9.7 8.6 14.2 13.5 15.7 23.2 6.1 5.7 13.8 20.8 7.0 5.5 15.7 9.2 9.9 12.0 7.0 18.8 2.3 12.5 5.3 6.5 70.2 19.8 7.2 149.0 181.5 4.3 3.4 19.6 9.9 12.2 11.0 17.5 15.2 7.7 4.5 11.0 12.8 32.3 0.9 3.4 1.3 1.0 3.0 1.3 6.7 2.2 1.3 6.2 9.1 2.2 1.1 0.8 3.4 3.6 1.4 5.3 1.9 53.8 49.4 45.3 63.9 50.6 135.3 71.2 57.3 75.0 50.3 62.7 55.2 7.8 6.4 4.8 52.5 21.5 9.1 11.7 7.5 10.2 24.2 6.9 9.5 5.4 1.5 7.8 12.9 16.7 9.3 7.9 15.1 11.7 3.6 58.7 4.3 18.3 8.6 1.2 5.2 79.5 4.5 10.6 7.9 5.1 6.9 2.5 9.7 4.2 3.5 9.9 42.1 130.5 5.6 10.2 6.0 27.8 88.6 5.3 13.1 19.6 34.7 16.3 21.7 6.2 52.8 70.5 6.8 6.6 3.8 4.7 8.2 6.5 24.7 4.0 21.6 6.6 7.8 13.8 22.4 41.0 13.1 10.4 13.3 7.7 19.3 6.5 13.1 INPP5K SKIP ENSG00000132376 "Inositol polyphosphate-5-phosphatase K" Q9BT40 17 1494577-1516742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Congenital muscular dystrophy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 96.1;Late spermatids: 345.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (7.47e-2)" "prognostic favorable (3.91e-4)" "unprognostic (8.91e-2)" "prognostic favorable (2.33e-5)" "unprognostic (3.25e-1)" "unprognostic (9.22e-2)" "unprognostic (1.50e-1)" "unprognostic (7.50e-2)" "unprognostic (2.00e-1)" "unprognostic (2.77e-2)" "prognostic favorable (1.47e-6)" "unprognostic (4.71e-2)" "unprognostic (9.35e-3)" "unprognostic (3.01e-2)" "unprognostic (7.20e-2)" "unprognostic (4.28e-3)" "unprognostic (1.04e-1)" 34.7 15.2 25.8 12.9 26.0 34.5 29.2 25.3 30.2 19.5 61.5 19.6 10.2 17.0 13.1 17.9 15.3 10.7 28.9 29.8 25.7 16.7 15.0 27.3 18.6 26.9 26.9 17.8 21.9 13.7 14.8 18.6 26.9 19.6 12.7 15.9 18.1 12.9 40.5 30.1 19.4 12.0 25.4 22.8 19.1 20.4 26.9 25.8 30.4 25.2 19.7 18.2 17.9 27.0 14.9 24.0 9.2 18.4 22.5 13.2 12.1 12.0 23.6 15.8 19.6 15.7 9.1 14.6 23.2 22.2 12.5 19.4 22.1 9.6 14.3 35.3 33.0 8.6 18.1 5.9 31.3 7.9 17.0 16.2 24.0 15.8 16.1 10.0 25.3 25.3 9.4 25.9 10.6 12.5 24.5 7.1 3.9 23.9 14.6 19.0 6.7 14.6 12.8 10.3 7.1 18.0 10.2 21.6 24.3 13.0 17.9 7.3 16.2 13.6 13.3 19.8 16.8 12.9 23.4 7.4 14.7 9.1 17.3 104.3 42.2 74.3 48.7 41.9 39.7 27.5 44.5 50.2 36.2 24.4 37.5 41.1 74.7 42.3 66.6 27.0 75.1 62.5 25.8 26.0 25.3 30.2 29.8 25.7 26.9 26.9 26.9 25.4 26.9 27.0 26.1 32.1 14.1 8.5 20.6 30.0 15.7 10.8 18.8 7.8 15.6 12.2 35.8 8.6 11.0 23.9 2.1 13.9 27.5 26.0 13.7 19.4 96.1 10.3 6.9 27.0 17.4 25.2 5.4 24.3 16.4 15.5 13.3 17.4 19.7 7.7 28.5 10.2 11.9 20.2 5.9 17.3 14.2 18.4 19.0 345.7 11.5 13.8 32.0 2.8 37.1 23.1 27.8 2.5 7.0 27.1 23.4 7.5 18.0 13.3 33.2 11.2 6.4 7.9 19.7 12.6 15.3 35.5 20.4 18.1 30.3 31.1 27.2 5.8 13.5 17.4 IQCH FLJ12476 ENSG00000103599 "IQ motif containing H" Q86VS3 15 67254786-67502260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.5" "Cell type enhanced" "Detected in many" "Astrocytes: 27.4;Early spermatids: 59.4;Excitatory neurons: 26.5;Late spermatids: 37.3;Respiratory ciliated cells: 30.3;Spermatocytes: 48.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040845 Uncertain Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA040845: AB_10672898" "unprognostic (2.69e-1)" "unprognostic (2.94e-3)" "unprognostic (3.11e-2)" "unprognostic (5.89e-5)" "unprognostic (2.48e-1)" "unprognostic (9.83e-2)" "unprognostic (2.57e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-1)" "unprognostic (3.25e-1)" "unprognostic (5.37e-2)" "unprognostic (1.70e-1)" "unprognostic (1.51e-3)" "unprognostic (2.81e-1)" "unprognostic (3.81e-2)" "unprognostic (6.16e-3)" "unprognostic (6.42e-2)" 0.3 1.1 0.7 0.3 0.8 0.1 1.6 0.7 1.4 0.9 4.2 0.5 0.2 0.8 2.6 0.5 6.8 0.6 0.9 0.7 1.8 2.2 1.0 0.9 0.4 2.5 2.2 0.3 0.7 3.7 2.0 0.4 1.6 0.6 0.7 5.0 0.6 0.8 0.5 0.6 0.1 0.3 2.0 0.4 1.1 11.5 1.9 1.0 4.1 0.0 0.2 0.7 0.3 1.4 1.7 1.6 0.8 1.3 1.1 2.6 0.6 0.9 0.7 1.3 0.9 0.1 1.9 1.2 0.8 1.5 1.5 2.8 2.6 1.0 2.3 0.2 1.2 0.3 1.6 0.2 1.7 0.5 0.3 1.7 1.1 2.9 2.8 1.3 0.5 3.1 2.6 1.1 1.0 1.8 0.4 0.4 0.9 1.0 1.1 0.3 1.2 1.3 1.6 0.7 2.6 0.7 1.2 1.6 4.8 1.6 4.3 0.3 1.2 1.5 0.7 2.4 1.0 2.5 3.2 0.3 3.1 1.3 1.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.8 0.7 1.4 0.7 1.8 2.5 2.2 1.6 2.0 1.9 1.4 0.7 3.2 1.1 27.4 0.3 1.3 1.0 1.6 1.8 1.5 2.7 2.2 1.1 0.0 2.8 1.8 8.4 0.2 0.3 0.4 0.0 1.0 59.4 15.9 1.1 0.9 0.0 0.4 26.5 0.8 0.5 0.7 8.2 2.0 0.0 0.7 0.0 0.0 0.3 1.7 18.2 0.5 4.1 0.0 0.7 37.3 0.9 0.3 0.0 8.4 1.0 1.1 0.0 9.0 9.5 0.7 0.0 0.7 0.5 0.3 0.2 2.2 30.3 5.4 0.0 1.5 0.6 48.8 18.2 1.2 0.4 0.3 0.4 4.2 0.4 1.0 ISG20 "CD25, HEM45" ENSG00000172183 "Interferon stimulated exonuclease gene 20" Q96AZ6 15 88635670-88656483 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, rRNA processing" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 188.9" "Cell type enhanced" "Detected in many" "Langerhans cells: 500.2;Paneth cells: 476.1;Plasma cells: 663.4;Urothelial cells: 538.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 202.9;Karpas-707: 117.4;SK-MEL-30: 718.4;U-698: 123.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.55e-3)" "unprognostic (1.19e-3)" "unprognostic (2.00e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (6.51e-5)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (4.54e-2)" "unprognostic (1.35e-3)" "prognostic favorable (1.85e-5)" "unprognostic (5.60e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (4.86e-8)" "unprognostic (1.04e-1)" "unprognostic (4.69e-2)" "unprognostic (3.39e-1)" "unprognostic (1.58e-2)" 22.4 8.1 7.0 78.3 9.0 41.3 21.7 8.0 11.3 12.9 6.0 28.5 77.2 7.4 9.5 30.1 15.2 38.7 14.5 6.7 8.2 15.1 28.2 62.8 188.9 10.7 8.0 19.1 10.5 2.6 28.6 12.5 8.5 18.7 9.5 0.2 25.1 11.2 5.0 11.2 65.6 3.3 8.2 148.5 69.1 6.7 9.2 87.2 31.0 3.1 64.0 27.4 13.4 9.3 9.1 15.0 0.6 0.2 0.2 0.6 2.4 0.4 7.0 41.4 56.7 4.5 20.8 202.9 10.5 0.6 20.2 3.1 1.1 4.2 1.7 65.1 0.6 0.7 6.3 9.6 26.8 0.3 0.2 3.7 9.3 13.3 10.3 1.2 6.5 15.1 0.8 117.4 0.0 16.4 0.7 1.7 2.1 34.2 30.1 8.8 1.0 39.7 3.3 2.3 0.7 1.0 2.4 84.9 718.4 0.4 3.8 4.7 8.6 1.6 5.0 0.3 3.0 81.2 22.4 123.2 1.8 4.0 8.7 141.9 37.4 75.9 303.2 63.5 402.9 1150.1 509.2 432.4 32.5 1184.0 365.5 390.7 1340.3 381.9 52.3 140.3 1244.0 369.5 7.0 9.0 8.0 11.3 6.7 8.2 10.7 8.0 8.5 8.2 9.2 9.3 70.4 48.1 46.7 0.0 424.2 178.7 152.3 98.5 3.4 0.2 84.3 58.8 1.9 51.5 97.0 3.7 0.0 2.3 378.8 213.5 1.9 66.1 23.7 318.8 29.4 86.6 37.6 108.2 0.6 148.9 71.5 63.5 130.0 254.1 7.6 2.9 21.8 13.3 8.2 0.0 1.9 144.1 168.9 34.4 500.2 5.2 2.1 72.2 225.9 5.6 195.4 0.0 224.6 1.5 3.1 307.1 476.1 1.9 663.4 318.7 131.8 8.6 118.4 0.2 26.3 14.6 26.9 1.1 2.9 9.9 287.0 52.0 318.4 4.9 19.7 538.6 ITPKB "IP3-3KB, IP3KB" ENSG00000143772 "Inositol-trisphosphate 3-kinase B" P27987 1 226631690-226739323 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 211.8;choroid plexus: 123.3" "Cell type enhanced" "Detected in many" "Adipocytes: 70.5;Astrocytes: 225.3;Microglial cells: 58.1;Oligodendrocytes: 110.6" "Cancer enhanced" "Detected in all" "melanoma: 44.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-MEL-30: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030273, HPA072923" Enhanced Approved Nucleoplasm NA NA 39000 "Cluster 49: Eosinophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA030273: AB_10601127, HPA072923: AB_2686558" "unprognostic (4.54e-2)" "unprognostic (3.85e-2)" "unprognostic (8.41e-3)" "unprognostic (9.37e-3)" "unprognostic (1.53e-1)" "prognostic favorable (1.72e-5)" "unprognostic (1.24e-1)" "prognostic favorable (6.65e-4)" "unprognostic (2.29e-1)" "unprognostic (9.57e-2)" "unprognostic (1.41e-2)" "unprognostic (1.75e-2)" "unprognostic (3.23e-3)" "unprognostic (2.90e-2)" "unprognostic (7.46e-2)" "unprognostic (6.54e-3)" "unprognostic (7.87e-2)" 29.6 4.5 148.6 15.6 205.6 19.0 19.6 152.0 104.8 28.0 123.3 45.3 6.6 48.8 17.0 14.0 27.0 10.0 16.2 109.0 149.5 15.1 3.2 22.5 29.0 211.8 188.0 9.5 5.8 7.1 6.8 15.9 169.1 14.5 6.7 0.6 30.2 22.7 12.4 19.4 24.9 31.7 154.6 23.5 21.2 3.7 207.6 33.2 8.3 12.3 20.3 38.6 15.6 133.7 4.7 5.0 7.9 9.1 6.1 3.9 2.1 1.2 5.5 2.5 5.7 0.7 5.8 21.6 7.4 1.2 0.5 6.8 10.1 4.1 1.2 3.0 6.9 9.6 5.5 0.0 2.3 8.8 16.4 4.4 5.9 2.8 2.5 6.9 17.2 10.8 0.1 2.9 0.3 4.5 16.7 12.1 17.3 3.5 8.0 6.4 14.2 4.8 18.2 7.5 4.6 6.0 3.8 2.8 47.2 7.7 11.7 10.1 12.0 3.2 2.4 2.9 7.6 0.2 8.0 25.8 0.8 8.0 12.1 0.9 0.9 5.4 2.6 1.3 2.3 1.2 3.2 2.7 0.6 1.8 4.7 3.5 3.4 2.1 2.5 0.5 1.9 2.0 148.6 205.6 152.0 104.8 109.0 149.5 211.8 188.0 169.1 154.6 207.6 133.7 70.5 0.0 7.4 225.3 16.0 12.2 4.8 3.1 7.4 0.3 7.0 5.3 8.5 1.5 4.5 7.3 0.0 0.6 28.9 1.2 3.9 2.2 2.8 4.7 6.8 42.2 4.2 5.2 2.4 2.4 2.3 8.9 3.6 4.5 10.1 21.8 27.8 1.0 19.8 0.0 6.9 2.8 2.0 16.0 38.0 22.9 7.2 14.4 19.6 58.1 10.2 1.2 28.8 10.6 110.6 2.7 3.7 9.4 11.8 5.1 2.0 0.6 2.6 0.1 0.0 5.9 16.3 0.9 4.7 5.3 10.1 0.4 35.2 3.7 3.1 2.7 KAT2B "GCN5, GCN5L, P/CAF, PCAF" ENSG00000114166 "Lysine acetyltransferase 2B" Q92831 3 20040446-20154404 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 165.2;Oligodendrocyte precursor cells: 418.2;Oligodendrocytes: 175.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002470, CAB004526, HPA055839, HPA073897" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "CAB004526: AB_2128417, HPA002470: , HPA055839: AB_2682938, HPA073897: " "unprognostic (2.91e-2)" "unprognostic (6.85e-3)" "unprognostic (9.05e-2)" "unprognostic (2.25e-1)" "unprognostic (2.66e-2)" "unprognostic (3.01e-3)" "unprognostic (2.44e-1)" "unprognostic (3.83e-3)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-3)" "unprognostic (7.13e-2)" "unprognostic (7.03e-2)" "unprognostic (2.26e-2)" "unprognostic (1.59e-1)" "unprognostic (5.16e-2)" "unprognostic (4.63e-2)" 17.9 9.9 38.7 15.4 46.5 48.0 10.3 39.1 40.3 14.9 33.8 13.8 17.7 12.3 8.1 27.4 11.7 12.6 35.9 34.4 42.2 16.6 39.3 16.2 22.4 41.7 44.9 27.7 18.7 51.0 10.2 13.7 43.0 14.5 12.5 33.9 37.6 13.0 60.2 14.3 21.5 13.6 37.1 19.8 13.9 2.7 42.2 23.6 14.4 56.1 20.1 11.9 15.1 45.1 2.7 6.9 3.8 6.2 15.1 14.2 8.8 8.8 13.0 9.1 13.3 2.1 4.5 24.0 3.6 16.7 11.5 2.0 9.4 2.8 7.6 21.8 9.0 21.0 10.7 0.7 7.1 3.2 26.2 6.1 5.0 7.9 5.1 16.0 8.8 5.8 13.7 32.9 13.0 3.3 7.0 6.4 1.6 6.7 6.8 9.1 7.1 5.1 12.4 14.2 1.9 4.1 4.9 7.9 30.5 5.9 8.2 14.2 8.5 15.3 6.1 5.8 10.1 12.3 27.6 5.7 13.9 13.8 33.0 0.6 0.4 1.3 1.5 0.7 1.5 0.4 1.3 1.1 0.4 0.8 0.4 0.8 2.4 0.5 0.5 1.2 2.2 0.3 38.7 46.5 39.1 40.3 34.4 42.2 41.7 44.9 43.0 37.1 42.2 45.1 15.5 32.1 20.8 165.2 11.9 8.5 11.3 2.2 3.4 14.6 5.5 5.0 64.1 4.3 10.4 5.5 4.2 7.3 19.5 16.6 11.7 3.8 3.8 6.4 5.7 14.6 11.5 52.2 22.4 4.4 1.1 11.7 3.6 13.1 10.8 12.3 20.7 33.6 7.7 15.2 32.1 7.3 4.1 22.8 23.3 1.8 6.5 16.0 17.8 52.5 11.1 14.8 14.4 418.2 175.4 3.3 2.4 5.3 19.9 7.1 24.7 6.2 12.7 11.9 6.6 25.2 9.0 0.8 1.4 10.0 12.9 9.9 23.5 2.9 3.8 8.0 KMT5B "CGI-85, SUV420H1" ENSG00000110066 "Lysine methyltransferase 5B" Q4FZB7 11 68154863-68213828 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 128.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063648 Supported Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA063648: AB_2685073" "unprognostic (5.82e-2)" "unprognostic (4.25e-2)" "unprognostic (2.54e-1)" "unprognostic (5.36e-3)" "unprognostic (3.52e-1)" "unprognostic (2.94e-1)" "unprognostic (1.83e-2)" "unprognostic (1.08e-1)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "unprognostic (5.54e-2)" "unprognostic (1.21e-1)" "unprognostic (3.79e-3)" "unprognostic (2.62e-1)" "unprognostic (4.26e-2)" "unprognostic (3.21e-2)" "prognostic favorable (9.30e-4)" 18.6 16.5 16.3 15.7 17.5 28.5 27.5 26.2 17.6 20.2 17.3 22.3 22.8 26.2 19.0 17.2 18.2 15.0 15.9 15.8 17.2 19.7 22.4 18.1 19.2 16.1 16.3 22.4 22.8 20.6 15.6 22.3 15.6 22.0 21.6 33.4 23.4 16.3 16.9 21.7 21.8 20.7 14.8 17.2 20.7 20.7 16.1 27.0 31.0 16.7 20.4 16.5 17.6 21.3 25.3 18.8 37.6 24.5 8.6 21.4 40.8 17.7 12.3 21.7 12.8 59.7 39.6 20.5 30.2 24.4 21.4 13.0 26.2 20.6 31.6 23.2 15.1 19.4 21.9 24.7 31.0 27.7 25.6 21.3 41.6 26.2 27.3 20.0 21.8 20.3 29.3 23.4 18.7 52.2 19.6 28.9 40.4 50.4 13.9 31.9 29.4 55.4 16.2 24.2 32.7 39.1 27.5 27.4 128.7 20.3 35.1 17.9 23.1 29.2 38.9 22.5 18.4 29.5 13.8 43.0 18.4 17.3 31.8 10.0 3.7 16.5 4.4 5.2 3.1 3.2 4.6 5.4 3.5 3.8 5.3 4.8 10.9 9.6 5.3 5.4 4.1 2.8 16.3 17.5 26.2 17.6 15.8 17.2 16.1 16.3 15.6 14.8 16.1 21.3 39.8 60.9 61.3 0.0 32.9 0.0 42.3 0.0 50.7 50.0 45.8 34.7 0.0 25.8 25.4 25.8 12.5 27.4 37.6 32.6 21.5 27.9 22.0 42.6 46.3 31.7 25.5 31.4 0.0 32.7 29.6 26.3 37.2 44.3 22.7 40.7 30.0 37.7 17.9 63.9 0.0 26.6 0.0 32.4 0.0 21.0 28.0 27.7 0.0 0.0 38.2 29.6 43.3 0.0 0.0 37.1 25.7 31.6 34.8 43.7 36.4 22.7 32.1 39.6 32.9 44.8 28.6 45.8 58.9 38.0 0.0 51.7 30.7 31.8 25.1 53.6 KRCC1 FLJ22333 ENSG00000172086 "Lysine rich coiled-coil 1" Q9NPI7 2 88027205-88064252 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045618, HPA052666" Approved Approved Nucleoli,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoli "HPA045618: AB_10960406, HPA052666: AB_2681907" "unprognostic (7.37e-3)" "unprognostic (1.30e-1)" "unprognostic (2.09e-1)" "unprognostic (1.01e-2)" "unprognostic (1.22e-1)" "unprognostic (2.59e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-2)" "unprognostic (1.46e-1)" "unprognostic (4.83e-2)" "unprognostic (2.22e-1)" "unprognostic (6.04e-2)" "unprognostic (1.99e-2)" "unprognostic (2.60e-1)" "unprognostic (1.91e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-3)" 28.2 21.0 20.1 28.7 22.8 10.1 38.4 21.7 28.0 33.0 20.7 45.9 32.0 23.9 41.7 32.2 27.1 22.2 31.7 19.9 21.6 31.9 43.6 21.9 38.0 23.2 22.0 24.6 28.6 34.1 15.7 21.9 23.7 25.2 43.8 14.5 24.8 26.0 29.1 25.8 35.7 22.9 21.8 30.7 27.2 15.2 21.7 31.5 33.2 34.6 32.4 24.4 24.9 24.9 29.4 17.8 27.4 20.1 64.1 75.3 20.2 45.5 50.3 23.7 23.1 1.6 38.5 41.4 16.0 28.9 36.1 14.8 6.3 9.4 26.7 43.7 8.7 8.0 4.4 2.8 46.7 12.2 5.5 38.0 46.3 15.9 33.7 61.9 27.1 32.9 11.5 20.2 51.7 25.0 14.1 16.9 20.9 42.3 11.8 28.3 5.0 4.5 36.0 15.8 21.1 21.3 17.3 23.7 54.8 20.1 16.7 49.2 38.2 28.0 2.1 46.5 14.5 45.3 33.6 32.5 30.1 32.0 67.5 59.4 21.6 77.7 18.8 23.8 21.7 36.6 23.0 23.2 25.7 32.5 25.8 21.0 35.8 31.6 21.5 22.5 34.3 16.8 20.1 22.8 21.7 28.0 19.9 21.6 23.2 22.0 23.7 21.8 21.7 24.9 24.2 35.3 41.7 29.4 61.8 33.0 32.6 49.9 53.5 11.9 50.9 50.9 41.3 40.0 49.0 35.0 2.1 46.1 24.8 109.1 60.7 50.5 16.7 34.4 37.8 31.6 41.6 28.2 14.5 70.9 16.3 42.5 17.3 30.9 43.1 28.4 37.9 59.5 48.6 10.1 13.9 56.8 26.4 40.3 39.8 5.3 47.8 38.8 28.4 44.0 53.6 35.9 58.7 34.7 53.5 51.4 79.6 43.2 29.6 62.6 60.4 76.0 62.6 5.4 19.7 40.3 29.7 41.0 20.7 45.4 42.6 41.9 37.2 32.2 72.4 26.4 LAMTOR5 "HBXIP, MGC71071, XIP" ENSG00000134248 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5" O43504 1 110401249-110407942 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1113.2;Proximal tubular cells: 2532.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006812 Approved Supported Cytosol NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA006812: AB_1079040" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (2.29e-1)" "unprognostic (3.54e-3)" "unprognostic (2.75e-1)" "unprognostic (5.29e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.97e-2)" "unprognostic (7.58e-2)" "prognostic favorable (7.23e-4)" "unprognostic (2.80e-1)" "unprognostic (2.93e-1)" "unprognostic (1.65e-2)" "unprognostic (3.77e-2)" "unprognostic (3.80e-3)" "prognostic favorable (5.52e-4)" "unprognostic (6.66e-2)" 143.6 134.9 152.2 79.5 156.3 250.3 127.7 167.7 179.0 107.7 168.0 108.3 85.7 86.2 162.6 121.0 93.2 101.9 269.7 150.9 163.6 433.9 150.2 115.2 114.1 159.6 155.4 121.0 95.3 192.3 141.2 120.7 157.9 109.4 110.9 140.0 100.1 77.6 260.3 98.7 102.2 81.5 165.1 126.0 127.8 88.6 161.4 102.2 107.8 277.3 122.6 124.2 109.4 168.1 272.1 223.2 197.3 118.5 325.3 245.3 196.1 224.4 176.5 186.8 176.6 196.0 130.0 214.5 233.0 220.9 228.4 107.5 203.4 189.2 229.8 231.4 227.9 157.7 257.1 402.1 247.1 227.7 188.0 216.3 287.3 193.9 122.6 236.2 227.7 156.9 189.3 196.0 275.8 443.0 208.7 274.7 140.1 151.8 366.9 141.9 355.1 164.2 439.0 302.0 145.4 189.6 198.8 287.7 516.4 169.5 111.0 317.3 217.8 140.5 182.9 355.7 214.4 204.5 250.7 277.2 459.1 225.6 329.6 295.4 223.1 485.8 125.9 229.5 112.1 345.3 146.6 137.6 187.9 322.3 127.1 134.4 347.7 149.2 225.0 321.5 181.1 250.6 152.2 156.3 167.7 179.0 150.9 163.6 159.6 155.4 157.9 165.1 161.4 168.1 131.2 160.3 174.4 16.3 208.2 307.8 284.1 661.5 101.3 111.0 186.0 197.9 597.6 211.6 371.9 445.1 25.0 424.5 141.5 225.1 1113.2 389.2 67.5 215.8 141.8 193.1 222.3 158.9 15.4 331.0 370.7 194.0 99.9 191.1 146.4 97.0 133.9 311.9 424.8 89.2 17.6 302.6 449.6 154.4 189.2 112.8 264.7 175.3 350.4 18.7 320.9 297.9 137.0 9.5 23.3 403.9 296.4 239.2 100.6 360.9 315.4 2532.5 340.9 150.5 170.9 168.2 185.2 297.9 361.3 121.3 322.5 500.5 125.7 163.2 252.0 441.8 LGALS3 "GALIG, LGALS2, MAC-2" ENSG00000131981 "Galectin 3" P17931 14 55124110-55145423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Immunity, Innate immunity, mRNA processing, mRNA splicing" "IgE-binding protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1194.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4097.0;Paneth cells: 3445.9;Proximal enterocytes: 4397.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 651.4;intermediate monocyte: 544.6;myeloid DC: 397.8;non-classical monocyte: 441.2;T-reg: 251.9" "Group enriched" "Detected in all" 13 "dendritic cells: 397.8;monocytes: 651.4;T-cells: 251.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 1169.3;CAPAN-2: 968.0;OE19: 1613.0;SK-MEL-30: 2329.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003162, CAB005191, HPA076528" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1900000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005191: AB_2136784, HPA003162: AB_1078937, HPA076528: " "unprognostic (1.42e-1)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" "unprognostic (3.15e-1)" "unprognostic (2.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.73e-3)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-3)" "unprognostic (5.97e-2)" "unprognostic (8.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.96e-2)" "unprognostic (2.65e-3)" "unprognostic (7.60e-3)" 404.5 72.0 111.4 219.8 111.8 346.9 323.1 110.7 148.1 331.4 104.3 1194.1 691.9 162.3 53.8 437.8 223.1 273.0 246.2 110.3 109.4 120.0 27.3 356.1 84.5 118.6 111.9 251.4 79.9 19.8 60.6 141.2 108.6 143.1 875.4 68.3 358.6 177.4 78.6 473.1 853.4 158.8 110.4 61.9 340.7 63.5 125.2 53.0 72.3 105.6 114.1 300.8 273.5 114.0 298.6 96.5 3.3 2.5 581.2 1169.3 344.9 226.7 496.2 64.0 113.2 225.4 968.0 0.7 121.3 272.8 114.6 289.0 6.1 245.4 37.5 357.1 4.4 1.0 104.7 103.8 446.8 1.0 1.1 363.4 375.2 73.9 152.8 145.1 101.5 0.7 1.4 283.1 148.8 218.5 1.3 74.4 5.6 1613.0 271.1 0.7 11.3 22.4 604.8 434.2 7.8 22.6 529.0 0.9 2329.1 16.2 242.8 31.4 180.5 297.8 41.5 112.0 4.4 154.0 535.6 2.8 426.8 18.6 31.8 18.5 651.4 32.4 15.7 544.6 99.7 11.5 58.4 44.2 397.8 4.7 2.5 8.3 28.7 24.2 441.2 9.6 251.9 449.6 111.4 111.8 110.7 148.1 110.3 109.4 118.6 111.9 108.6 110.4 125.2 114.0 1157.4 721.1 359.8 33.3 42.0 631.3 624.1 1278.9 241.9 2.9 307.3 478.7 218.2 258.7 1463.3 119.5 0.0 766.1 38.8 4097.0 673.1 605.9 21.7 636.2 742.7 397.8 173.4 578.1 0.2 1057.8 1051.7 666.3 281.4 846.8 580.5 6.3 64.6 2.3 1137.4 1.7 0.5 1733.8 1778.1 287.8 844.6 44.4 555.7 651.2 848.4 14.0 639.1 300.1 9.2 2.0 0.3 1289.6 3445.9 384.0 77.4 708.4 4397.2 81.3 1506.5 14.7 144.7 220.2 521.0 11.5 6.6 524.8 797.6 483.8 119.5 2.9 1880.1 1139.7 LONP1 "hLON, LonHS, PIM1, PRSS15" ENSG00000196365 "Lon peptidase 1, mitochondrial" P36776 19 5691834-5720572 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Hydrolase, Protease, Serine protease" "Cataract, Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 196.2" "Cell type enhanced" "Detected in all" "Theca cells: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002034, HPA002192" Supported Enhanced Nucleoplasm,Mitochondria No No 7900 "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA002034: AB_2756304, HPA002192: AB_1079695" "unprognostic (6.52e-2)" "unprognostic (1.12e-1)" "unprognostic (2.43e-1)" "unprognostic (2.43e-2)" "unprognostic (2.84e-1)" "unprognostic (2.38e-1)" "unprognostic (1.66e-3)" "unprognostic (5.56e-2)" "unprognostic (2.71e-1)" "unprognostic (7.57e-2)" "unprognostic (4.04e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (2.11e-1)" 30.4 196.2 31.5 22.2 32.7 23.7 27.2 34.6 42.8 24.4 39.9 27.9 22.6 25.2 14.1 27.7 22.6 15.4 76.0 30.8 35.7 43.2 79.1 25.6 24.1 37.6 35.8 26.6 38.2 35.2 41.5 18.5 37.9 26.4 13.2 13.0 30.8 16.6 69.3 28.9 25.5 14.7 30.8 29.5 33.7 24.2 37.2 17.5 34.6 40.7 14.5 28.2 22.4 33.0 108.4 111.0 35.6 114.0 41.4 29.2 110.4 67.2 52.7 71.0 86.0 96.3 37.7 134.3 91.4 70.6 68.0 45.0 92.1 81.1 34.2 80.0 78.0 74.5 97.5 127.6 190.4 169.7 74.9 55.0 114.6 67.5 132.6 34.1 57.5 183.9 200.9 259.4 33.0 71.8 85.5 101.6 127.6 43.6 143.1 89.4 50.9 146.6 39.3 63.9 94.2 94.1 59.4 85.2 242.2 24.9 50.3 211.9 41.2 36.0 39.2 100.7 99.2 272.3 182.6 121.4 161.7 185.0 66.2 4.5 2.4 0.5 3.4 3.7 2.3 4.0 3.1 3.4 2.6 3.7 3.8 2.6 0.3 2.7 1.5 3.9 2.7 1.7 31.5 32.7 34.6 42.8 30.8 35.7 37.6 35.8 37.9 30.8 37.2 33.0 12.6 6.4 13.1 18.3 14.1 8.3 11.1 14.9 11.4 26.9 14.2 12.7 19.8 15.7 14.3 27.6 6.2 28.8 8.4 40.1 46.9 33.9 6.5 24.0 16.3 15.3 11.4 17.1 13.5 28.0 31.9 13.3 29.6 25.6 5.7 51.1 11.4 47.0 30.8 21.9 17.4 26.4 22.4 14.6 8.6 6.3 12.8 16.4 14.2 9.4 17.8 24.9 8.2 10.6 15.7 26.0 16.8 17.3 17.6 16.8 27.5 50.2 17.0 26.5 19.7 17.9 24.7 12.0 14.4 11.0 10.7 35.0 10.7 85.0 35.1 11.4 LPGAT1 "FAM34A, FAM34A1, KIAA0205, NET8" ENSG00000123684 "Lysophosphatidylglycerol acyltransferase 1" Q92604 1 211743457-211830763 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 416.1;Oligodendrocytes: 474.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.60e-2)" "unprognostic (1.04e-1)" "unprognostic (3.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.36e-1)" "unprognostic (1.66e-1)" "unprognostic (9.47e-3)" "unprognostic (1.12e-2)" "unprognostic (1.08e-1)" "unprognostic (2.67e-1)" "unprognostic (2.54e-1)" "unprognostic (1.31e-1)" "unprognostic (1.64e-2)" "unprognostic (1.18e-1)" "unprognostic (2.02e-1)" "unprognostic (1.50e-2)" "unprognostic (3.70e-2)" 20.0 19.7 17.0 13.4 29.4 20.0 13.4 13.8 19.5 11.4 21.3 9.3 23.6 9.0 10.1 7.7 8.5 12.1 11.8 14.6 18.0 9.8 36.4 8.8 10.5 18.2 22.4 6.0 13.7 13.9 8.9 9.1 17.8 10.1 10.3 41.1 9.4 12.4 9.9 6.2 35.0 12.2 13.2 16.7 7.4 22.3 21.7 8.2 25.8 14.9 9.8 13.8 7.4 39.2 28.2 30.4 9.8 23.5 17.4 24.2 14.1 19.7 31.2 18.0 16.5 9.1 22.9 11.5 11.3 30.7 20.1 15.0 33.2 17.6 22.6 22.6 11.2 12.0 24.5 20.8 20.9 29.9 19.8 14.3 21.2 16.6 21.6 33.1 21.9 16.2 14.0 0.2 24.1 8.8 11.4 11.1 10.7 12.0 4.9 27.2 38.8 3.5 20.1 23.0 56.6 29.3 32.3 33.9 33.9 15.1 17.3 19.3 21.3 32.7 14.4 30.3 32.5 16.1 21.2 30.2 16.2 25.0 22.8 12.3 2.7 16.1 1.4 2.2 1.1 1.8 0.9 1.0 3.2 1.0 0.2 0.8 12.1 5.3 1.7 2.4 0.2 0.9 17.0 29.4 13.8 19.5 14.6 18.0 18.2 22.4 17.8 13.2 21.7 39.2 50.0 28.9 21.0 28.7 42.2 12.2 77.7 11.5 38.1 206.3 32.2 18.9 40.4 72.9 16.9 12.9 62.6 2.3 73.2 25.3 1.9 71.9 416.1 39.1 39.2 31.6 13.8 15.3 73.5 59.4 4.7 30.9 19.9 28.0 12.7 22.0 25.0 56.2 20.9 35.3 92.3 14.6 26.4 49.7 27.3 60.2 47.2 44.9 30.2 46.9 58.6 34.7 49.4 70.4 474.0 47.8 19.5 55.7 15.0 53.3 126.1 24.2 38.2 127.6 19.7 47.1 33.2 67.2 33.3 30.7 7.5 1.1 32.5 129.4 23.4 63.1 LRMDA "C10orf11, CDA017, OCA7" ENSG00000148655 "Leucine rich melanocyte differentiation associated" Q9H2I8 10 75431624-76560168 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation Albinism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 61.5;epididymis: 59.5" "Cell type enhanced" "Detected in many" "Adipocytes: 42.4;Distal tubular cells: 33.2;Endometrial ciliated cells: 27.8;Hofbauer cells: 56.9;Proximal tubular cells: 113.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 57.6;eosinophil: 22.1;intermediate monocyte: 28.8;myeloid DC: 67.5;non-classical monocyte: 17.1" "Group enriched" "Detected in many" 7 "dendritic cells: 67.5;granulocytes: 22.1;monocytes: 57.6" "Cell line enhanced" "Detected in many" "Hep G2: 46.3;HMC-1: 34.0;NB-4: 65.6;SK-MEL-30: 93.0;THP-1: 48.7;U-937: 43.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047446, HPA050419" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA047446: AB_2680050, HPA050419: AB_2756316" "unprognostic (1.04e-1)" "unprognostic (8.03e-2)" "unprognostic (2.40e-1)" "unprognostic (7.97e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.31e-1)" "unprognostic (8.57e-3)" "unprognostic (5.86e-2)" "unprognostic (6.80e-2)" "unprognostic (8.34e-2)" "unprognostic (1.26e-1)" "unprognostic (7.34e-3)" "unprognostic (7.26e-2)" "unprognostic (6.50e-2)" "unprognostic (4.98e-3)" "unprognostic (3.64e-2)" 16.1 61.5 8.0 5.4 8.6 27.5 10.3 7.7 7.7 12.0 4.7 8.1 5.8 6.4 59.5 7.5 9.7 10.2 13.3 7.8 8.4 20.6 35.8 12.8 5.2 11.5 9.6 13.0 24.9 20.6 10.1 12.7 11.8 10.7 7.2 2.4 9.2 10.0 2.7 3.1 4.5 9.0 10.2 10.5 16.8 3.7 10.9 4.1 18.6 4.8 5.1 11.4 4.5 11.5 0.3 5.7 0.2 0.1 2.9 3.5 0.1 0.7 0.0 0.3 0.5 7.6 13.4 0.0 25.8 0.0 0.1 0.3 0.0 0.0 0.1 0.5 1.6 1.6 2.9 46.3 1.1 9.4 34.0 1.4 1.0 0.6 0.1 5.5 0.8 0.1 0.0 1.4 0.1 1.0 0.1 65.6 0.3 3.9 2.2 0.1 0.2 0.1 0.6 8.3 0.3 0.4 8.1 0.0 93.0 0.2 0.5 48.7 0.9 0.3 3.1 2.4 5.3 0.4 0.2 0.2 22.6 43.6 11.3 6.4 57.6 22.1 0.1 28.8 0.3 0.1 0.0 0.0 67.5 0.1 0.1 0.1 3.2 7.1 17.1 0.5 0.2 18.9 8.0 8.6 7.7 7.7 7.8 8.4 11.5 9.6 11.8 10.2 10.9 11.5 42.4 22.4 19.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.1 5.7 0.0 0.0 3.7 12.9 0.0 1.1 0.8 0.0 33.2 16.6 0.0 27.8 2.5 13.2 0.0 0.0 0.0 15.8 0.8 4.5 0.0 10.0 7.6 16.1 0.0 0.0 56.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.1 0.0 0.0 113.4 6.6 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 1.2 0.6 25.7 0.0 0.0 LRRC39 "MGC14816, myomasp" ENSG00000122477 "Leucine rich repeat containing 39" Q96DD0 1 100148448-100178273 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 107.0;retina: 117.9;skeletal muscle: 431.0;tongue: 172.9" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 96.4;Cone photoreceptor cells: 60.5;Early spermatids: 204.8;Hofbauer cells: 76.4;Inhibitory neurons: 62.2;Rod photoreceptor cells: 74.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA077159 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA077159: AB_2732333" "unprognostic (7.68e-2)" "unprognostic (3.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.91e-1)" "unprognostic (6.40e-2)" "unprognostic (1.27e-1)" "unprognostic (4.07e-3)" "unprognostic (1.58e-2)" "unprognostic (1.87e-2)" "unprognostic (1.45e-1)" "unprognostic (3.16e-3)" "unprognostic (3.08e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-1)" "unprognostic (8.17e-2)" "unprognostic (1.79e-1)" "unprognostic (3.38e-4)" 2.2 9.8 3.5 1.5 3.6 1.5 1.9 2.8 4.7 1.6 1.1 1.8 1.0 1.4 1.4 4.2 1.7 1.1 107.0 2.8 3.7 1.7 2.6 1.7 2.4 3.8 2.9 1.6 1.6 5.3 2.3 4.2 2.5 4.2 0.6 117.9 2.9 0.5 431.0 3.8 1.7 0.7 1.8 2.3 1.6 6.5 4.2 1.1 1.9 172.9 0.9 1.7 1.3 3.6 0.4 0.5 1.8 2.4 0.4 0.8 1.5 0.8 0.3 0.3 0.7 0.1 1.1 2.0 0.9 0.3 0.4 1.1 0.2 0.2 0.7 0.3 1.7 0.9 2.4 0.4 0.2 0.6 1.1 1.5 0.3 0.3 0.1 0.5 0.3 1.5 0.9 1.7 0.5 0.3 1.0 2.4 0.8 0.5 0.6 1.0 0.8 0.8 0.3 0.6 0.7 2.5 0.5 0.7 6.7 0.6 0.6 1.4 0.5 1.0 0.9 1.3 1.6 3.2 1.6 0.7 1.7 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.6 2.8 4.7 2.8 3.7 3.8 2.9 2.5 1.8 4.2 3.6 0.3 0.0 1.3 6.8 0.4 0.1 0.1 0.0 0.0 13.1 0.3 0.1 96.4 0.0 0.0 0.0 60.5 0.5 0.3 0.3 0.0 0.2 204.8 0.2 0.5 1.8 0.0 0.0 14.6 0.6 0.6 3.8 0.0 0.5 1.3 0.2 0.7 0.2 76.4 18.5 62.2 0.0 0.0 0.3 0.0 21.7 2.1 8.0 0.0 1.9 0.8 8.1 1.0 5.5 10.2 0.3 0.1 0.4 0.5 0.1 0.0 0.0 0.7 74.2 0.0 8.6 1.4 9.9 1.2 0.0 0.1 0.7 0.4 0.4 0.0 0.0 LRRC8D "FLJ10470, LRRC5" ENSG00000171492 "Leucine rich repeat containing 8 VRAC subunit D" Q7L1W4 1 89821014-89936611 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.4" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 80.8;Oligodendrocyte precursor cells: 146.8;Oligodendrocytes: 346.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA No "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (2.92e-3)" "unprognostic (9.50e-2)" "unprognostic (1.06e-3)" "prognostic unfavorable (3.21e-5)" "unprognostic (4.98e-2)" "unprognostic (7.03e-2)" "unprognostic (7.71e-3)" "unprognostic (7.74e-2)" "unprognostic (9.67e-2)" "unprognostic (1.01e-2)" "unprognostic (1.42e-1)" "unprognostic (2.77e-1)" "unprognostic (4.91e-2)" "unprognostic (9.52e-3)" "unprognostic (1.23e-1)" "unprognostic (2.65e-2)" "unprognostic (9.61e-2)" 5.9 26.9 25.1 15.8 45.2 14.2 12.9 39.2 37.0 12.1 9.6 17.9 19.0 8.8 10.3 7.9 7.8 8.0 7.6 30.6 30.2 25.9 23.5 9.8 24.9 43.3 40.3 5.9 13.0 7.7 16.3 10.3 41.3 5.6 18.2 12.0 24.5 5.8 8.7 5.6 18.0 11.4 39.7 23.9 11.5 10.3 36.5 27.7 15.8 3.4 20.4 11.2 3.3 80.4 73.5 47.0 18.8 44.5 32.9 27.7 63.5 49.1 73.9 27.3 34.1 20.2 18.3 57.7 54.4 82.1 31.0 93.7 43.6 58.9 34.4 45.3 24.1 67.8 40.4 43.2 64.2 78.2 20.5 17.4 48.1 23.3 50.3 37.6 47.1 32.8 37.6 17.7 30.1 22.0 32.5 50.4 32.6 16.4 42.6 43.6 27.3 41.5 69.2 25.7 35.0 24.4 61.0 62.4 137.8 32.4 15.0 76.4 21.0 29.1 9.9 60.0 37.6 21.4 39.5 34.7 11.3 97.0 26.2 0.0 8.9 1.6 7.0 10.4 11.6 6.9 16.0 8.5 8.1 5.6 15.2 11.5 3.5 13.1 8.4 9.4 17.4 10.6 25.1 45.2 39.2 37.0 30.6 30.2 43.3 40.3 41.3 39.7 36.5 80.4 2.9 3.2 1.7 35.3 10.8 6.0 1.4 12.7 15.9 6.6 8.4 7.4 3.0 8.6 6.2 12.9 2.1 4.0 14.8 26.6 7.9 5.7 0.7 3.1 2.9 5.5 7.8 17.0 66.8 8.6 9.9 3.8 6.1 3.4 5.7 7.8 7.9 30.1 11.8 3.3 80.8 10.8 10.2 21.9 5.5 0.8 1.2 19.1 10.6 68.4 36.3 6.3 10.3 146.8 346.4 5.4 11.3 3.8 8.0 4.1 22.5 12.5 7.2 7.6 6.6 10.7 2.9 0.3 1.9 7.1 1.1 1.8 11.0 22.4 11.2 1.8 LZTFL1 BBS17 ENSG00000163818 "Leucine zipper transcription factor like 1" Q9NQ48 3 45823316-45916042 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 119.0;Endometrial ciliated cells: 56.7;Respiratory ciliated cells: 142.2;Spermatocytes: 170.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043466, HPA048447" Enhanced Supported Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA043466: AB_2678491, HPA048447: AB_2680398" "unprognostic (1.64e-2)" "unprognostic (1.34e-1)" "unprognostic (3.14e-2)" "unprognostic (1.26e-2)" "unprognostic (2.65e-2)" "unprognostic (5.42e-2)" "unprognostic (1.15e-2)" "unprognostic (2.26e-2)" "unprognostic (4.20e-2)" "unprognostic (2.94e-2)" "unprognostic (7.83e-2)" "unprognostic (5.32e-2)" "unprognostic (1.30e-3)" "unprognostic (6.27e-3)" "unprognostic (8.31e-2)" "unprognostic (4.27e-3)" "unprognostic (4.19e-1)" 5.2 6.2 7.1 4.5 8.2 6.0 12.4 5.8 10.1 12.4 17.5 5.7 7.0 13.2 15.0 5.5 18.9 6.9 4.6 8.7 7.7 12.0 10.0 9.0 4.7 6.7 7.3 11.4 5.6 14.2 11.7 5.9 6.5 7.9 6.2 15.8 7.2 8.8 2.8 6.0 5.7 8.4 6.6 6.0 5.8 25.4 7.1 30.7 18.9 3.5 5.7 4.7 4.1 6.9 10.1 5.0 7.8 5.1 7.2 17.9 4.0 5.3 10.0 12.2 15.8 2.4 7.5 2.7 3.1 7.5 15.2 6.4 9.5 8.6 15.9 0.2 6.1 2.6 6.7 4.5 9.4 9.9 2.8 9.3 29.6 16.8 10.8 7.8 6.0 16.5 8.9 6.7 5.9 1.6 34.1 9.6 8.1 6.7 4.2 3.7 0.8 10.7 14.7 4.7 5.4 11.0 7.0 6.0 13.2 8.7 7.1 18.3 9.9 4.5 3.1 12.2 7.1 18.3 10.0 0.1 14.3 11.7 3.7 0.0 0.9 0.4 1.3 1.2 1.7 4.3 1.1 1.2 2.3 2.4 1.8 1.7 1.0 1.5 0.8 2.5 2.0 1.6 7.1 8.2 5.8 10.1 8.7 7.7 6.7 7.3 6.5 6.6 7.1 6.9 7.6 28.9 25.2 7.8 10.8 13.5 10.5 14.9 12.0 7.9 16.9 14.9 7.6 11.5 23.6 14.7 14.6 3.1 8.4 3.7 15.6 13.3 119.0 56.7 10.5 10.2 11.4 11.6 22.3 6.9 5.1 13.3 6.1 12.3 8.2 10.1 11.7 13.5 6.6 23.5 9.9 10.4 10.2 7.3 7.0 19.2 9.9 5.3 8.8 5.6 10.8 17.8 7.2 6.6 12.2 5.6 5.6 13.5 11.6 5.9 3.2 23.0 142.2 14.6 13.1 15.7 9.2 170.0 24.1 8.4 9.9 2.1 10.5 14.2 8.9 5.6 LZTS1 FEZ1 ENSG00000061337 "Leucine zipper tumor suppressor 1" Q9Y250 8 20246165-20303963 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 14.8;parathyroid gland: 54.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 17.6;Excitatory neurons: 26.2;Horizontal cells: 20.2;Melanocytes: 19.6;Rod photoreceptor cells: 18.5;Sertoli cells: 65.7;Smooth muscle cells: 15.4" "Cancer enhanced" "Detected in all" "melanoma: 59.2" "Group enriched" "Detected in many" 5 "amygdala: 13.1;basal ganglia: 11.6;cerebral cortex: 14.8;hippocampal formation: 14.5;white matter: 9.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 19.7;SK-MEL-30: 75.0;U-698: 23.2;WM-115: 50.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 23.2;basal ganglia: 66.8;cerebral cortex: 45.5;hippocampal formation: 36.3;olfactory bulb: 26.7" "HPA006294, HPA022046" Approved Approved "Nucleoli,Plasma membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Nucleoli "HPA006294: AB_1079288, HPA022046: AB_1853455" "unprognostic (7.76e-2)" "unprognostic (1.02e-1)" "unprognostic (3.49e-3)" "prognostic unfavorable (3.03e-4)" "unprognostic (6.27e-2)" "unprognostic (1.96e-1)" "unprognostic (7.29e-2)" "unprognostic (5.76e-2)" "unprognostic (1.41e-2)" "unprognostic (9.06e-3)" "unprognostic (6.81e-2)" "unprognostic (3.63e-2)" "prognostic unfavorable (9.28e-6)" "unprognostic (3.35e-2)" "unprognostic (2.71e-1)" "unprognostic (1.11e-1)" "unprognostic (6.82e-3)" 3.7 1.7 13.1 1.5 11.6 0.1 3.0 0.0 14.8 2.0 0.0 1.3 0.5 2.9 0.9 5.3 1.6 3.5 5.0 14.5 0.6 4.7 0.7 7.0 1.1 0.0 0.1 1.2 1.5 54.2 2.2 6.5 0.3 2.8 0.4 3.5 1.4 1.1 1.9 4.6 0.9 2.5 0.0 0.5 1.4 7.5 2.3 1.9 2.7 2.0 0.5 2.3 1.7 9.2 0.1 0.0 9.7 8.3 0.0 0.0 1.2 5.0 0.1 4.3 3.7 0.3 0.1 11.1 3.5 3.1 1.6 0.2 0.5 0.2 2.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 1.7 0.9 0.1 1.8 0.0 0.6 0.0 11.7 0.0 0.1 14.4 0.0 19.7 0.1 12.2 0.0 0.0 0.0 15.6 0.0 2.7 0.4 14.8 12.9 0.0 0.0 75.0 8.2 0.1 0.4 0.0 5.1 3.5 0.1 1.5 0.1 0.1 23.2 0.1 1.1 50.8 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.1 11.6 0.0 14.8 14.5 0.6 0.0 0.1 0.3 0.0 2.3 9.2 3.9 0.0 0.0 1.6 0.0 1.3 0.8 1.0 17.6 1.8 0.3 11.3 4.6 0.0 0.1 0.0 4.2 7.1 0.4 0.0 1.9 0.0 0.5 0.6 1.3 3.2 0.0 0.0 26.2 0.0 2.3 2.4 0.0 0.5 0.0 3.5 0.0 0.0 0.9 20.2 2.9 0.0 2.0 0.0 0.0 0.8 1.2 0.2 19.6 1.9 0.0 0.9 0.0 6.0 0.8 0.0 0.0 0.4 0.0 0.1 0.0 0.4 0.0 18.5 65.7 1.1 15.4 0.2 1.1 7.3 0.1 0.8 1.4 2.5 0.0 0.0 LZTS2 "KIAA1813, LAPSER1" ENSG00000107816 "Leucine zipper tumor suppressor 2" Q9BRK4 10 100996618-101007836 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 70.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044956 Approved Approved "Plasma membrane,Cytosol" No Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA044956: AB_10795989" "unprognostic (1.42e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (8.18e-2)" "unprognostic (4.64e-2)" "unprognostic (1.56e-1)" "unprognostic (5.49e-3)" "unprognostic (3.56e-1)" "unprognostic (7.57e-2)" "unprognostic (4.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.63e-2)" "unprognostic (1.86e-1)" "unprognostic (5.46e-3)" "unprognostic (1.76e-3)" 69.9 66.0 46.8 14.9 65.5 14.4 63.3 58.0 54.1 74.3 25.8 96.3 17.5 90.3 17.7 41.0 69.2 19.8 58.9 41.2 45.8 51.8 18.0 57.1 12.1 63.7 64.3 78.6 29.5 29.1 43.6 28.5 58.5 69.5 8.9 5.9 44.3 40.6 37.8 48.9 43.0 26.6 49.0 44.4 54.9 36.2 64.1 10.8 57.6 18.0 8.1 84.1 54.4 78.9 32.9 43.1 34.6 59.7 45.0 36.3 70.8 38.7 72.8 31.9 36.0 50.5 26.6 13.1 35.1 52.5 23.0 54.6 21.5 28.2 7.8 12.8 31.9 12.1 46.4 66.3 63.6 6.4 15.2 66.1 20.2 25.1 30.1 67.3 32.8 15.6 38.7 7.3 28.7 31.6 5.8 15.8 38.8 12.6 35.2 74.7 101.3 13.5 24.4 39.3 8.4 62.8 26.3 11.9 99.9 18.6 61.0 51.6 42.1 37.9 42.6 40.5 20.7 14.0 10.2 3.3 64.0 17.7 19.4 0.0 0.7 0.4 2.7 0.4 3.7 2.3 3.4 3.0 1.1 2.9 3.5 3.0 0.3 2.9 0.1 1.8 3.0 1.5 46.8 65.5 58.0 54.1 41.2 45.8 63.7 64.3 58.5 49.0 64.1 78.9 34.7 16.0 10.5 20.2 5.3 13.4 9.0 12.4 19.4 14.4 21.7 20.3 5.2 11.5 9.4 5.5 6.2 18.6 1.9 8.0 7.9 19.1 6.8 7.9 20.5 22.9 16.7 5.0 6.8 12.6 13.2 21.8 14.8 13.0 1.3 38.9 18.5 2.6 22.2 18.5 7.7 17.8 16.2 7.2 9.2 4.1 25.7 8.4 16.0 13.1 4.8 18.9 4.1 9.0 70.3 13.3 7.9 29.3 5.4 18.1 6.5 8.3 6.1 4.0 26.3 21.1 40.7 3.8 15.0 10.8 12.1 47.1 6.0 26.9 15.1 9.7 MAFF hMafF ENSG00000185022 "MAF bZIP transcription factor F" Q9ULX9 22 38200767-38216507 "Predicted intracellular proteins, Transcription factors" "Stress response, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 682.0;Syncytiotrophoblasts: 479.1;Urothelial cells: 409.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 23.9;neutrophil: 8.7;NK-cell: 21.1" "Group enriched" "Detected in many" 6 "granulocytes: 23.9;NK-cells: 21.1" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 79.2;SK-MEL-30: 104.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 5.6" "CAB025341, HPA055371" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 10: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm Mitochondria "CAB025341: , HPA055371: AB_2682797" "prognostic favorable (4.32e-4)" "unprognostic (2.54e-1)" "unprognostic (1.07e-1)" "unprognostic (2.67e-1)" "unprognostic (1.99e-2)" "unprognostic (2.13e-3)" "unprognostic (5.06e-3)" "unprognostic (3.42e-3)" "unprognostic (7.83e-3)" "unprognostic (5.36e-3)" "unprognostic (1.23e-3)" "unprognostic (2.44e-1)" "unprognostic (3.24e-2)" "unprognostic (2.84e-1)" "unprognostic (4.08e-2)" "unprognostic (1.07e-1)" "unprognostic (2.68e-2)" 102.9 22.8 9.4 12.9 9.0 36.2 69.9 9.3 10.7 37.4 9.4 26.6 8.1 28.8 2.1 53.4 64.2 41.4 53.8 8.2 11.9 32.0 30.8 59.2 4.7 14.5 10.0 53.9 19.7 5.3 19.5 34.5 13.4 39.5 10.3 19.6 28.6 5.5 73.3 45.7 19.6 23.2 10.5 9.3 45.4 3.0 14.1 7.4 25.0 6.9 11.3 53.8 41.4 16.6 20.8 3.3 4.4 6.6 6.9 21.3 20.6 41.4 54.2 19.8 21.0 6.1 16.0 0.7 3.9 16.9 29.5 13.5 1.1 15.7 33.2 3.9 0.6 2.1 2.1 5.2 18.0 1.3 7.1 9.3 25.7 79.2 43.6 17.6 42.1 1.9 4.2 18.6 15.6 4.9 0.8 5.2 3.3 22.0 16.8 1.4 3.8 4.3 19.9 30.6 2.2 3.7 6.1 15.4 104.9 10.7 3.3 1.5 57.9 24.7 19.2 18.8 13.7 7.2 8.0 0.7 37.4 1.4 15.9 23.9 0.4 0.3 2.9 0.7 2.8 0.8 1.7 2.1 1.4 0.5 2.1 1.6 8.7 21.1 3.5 0.2 0.7 1.8 9.4 9.0 9.3 10.7 8.2 11.9 14.5 10.0 13.4 10.5 14.1 16.6 215.4 54.5 43.4 1.0 19.3 125.9 344.1 56.8 169.0 2.9 302.9 214.1 18.6 67.2 49.5 11.0 0.0 37.8 112.5 134.2 7.9 49.9 0.5 284.7 149.3 97.3 104.8 5.7 0.8 24.2 77.5 134.7 132.5 682.0 22.2 11.5 22.1 8.2 26.0 0.0 1.6 112.5 34.6 14.0 131.1 0.4 9.9 113.5 58.7 1.0 10.2 36.0 17.5 1.5 1.3 76.0 181.0 3.8 25.8 258.4 67.6 3.7 37.9 3.6 19.7 265.2 153.1 2.4 1.0 139.5 103.1 479.1 59.0 8.4 75.5 409.2 MAGED2 "11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386" ENSG00000102316 "MAGE family member D2" Q9UNF1 X 54807599-54816015 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Tumor antigen" "Bartter syndrome, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Granulosa cells: 1684.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031572, HPA031573" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol No No 120000 "Cluster 44: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nucleoli, Cytosol" "HPA031572: AB_10599819, HPA031573: AB_10602181" "unprognostic (1.33e-1)" "unprognostic (8.60e-2)" "unprognostic (3.32e-1)" "unprognostic (1.69e-3)" "unprognostic (4.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.41e-3)" "unprognostic (1.39e-1)" "unprognostic (2.97e-1)" "prognostic favorable (2.88e-4)" "prognostic favorable (2.82e-4)" "unprognostic (6.34e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (9.43e-4)" "unprognostic (1.58e-1)" "unprognostic (9.77e-2)" "unprognostic (3.58e-1)" 81.6 125.1 102.3 52.8 97.8 31.8 162.6 104.9 112.2 174.5 111.7 106.8 54.3 134.3 101.9 67.4 149.0 94.3 142.2 95.5 121.9 141.0 57.5 85.9 48.0 125.4 118.4 255.9 75.5 148.0 195.3 177.1 128.8 208.8 53.5 74.4 103.3 169.9 88.9 60.5 62.5 140.6 108.5 60.8 77.6 63.1 110.1 68.8 149.2 91.4 46.2 111.7 95.7 108.9 34.0 61.4 373.7 111.0 171.6 229.5 66.8 137.9 243.7 106.4 187.5 62.3 84.4 47.1 361.2 279.0 88.5 45.2 106.5 104.2 76.1 84.5 87.0 100.0 68.6 122.1 145.5 25.4 71.8 310.4 43.0 109.3 55.5 223.6 209.9 55.2 24.5 55.7 207.6 94.0 57.0 41.9 134.7 59.1 72.4 37.4 132.9 68.2 148.5 25.3 56.6 149.5 54.7 62.4 330.6 437.5 263.1 42.9 185.0 90.4 141.3 135.9 39.5 35.7 32.7 34.5 132.0 66.7 477.6 178.5 31.9 132.1 119.1 80.0 91.7 59.2 98.1 112.1 41.1 63.9 97.3 112.0 11.8 108.6 140.8 25.8 108.9 127.4 102.3 97.8 104.9 112.2 95.5 121.9 125.4 118.4 128.8 108.5 110.1 108.9 77.9 44.8 42.8 17.6 37.4 42.4 96.4 198.6 43.3 69.8 123.3 97.8 60.5 44.3 175.4 77.3 29.2 231.5 36.9 11.9 246.5 107.4 3.4 42.4 96.8 116.4 58.3 10.3 12.9 53.7 133.7 151.7 20.9 57.1 102.1 1684.0 79.9 16.2 69.1 138.0 20.3 48.8 173.0 19.5 47.4 17.4 233.3 41.1 158.3 21.5 42.1 175.9 44.3 17.6 20.4 47.9 33.7 320.4 46.7 75.2 25.5 149.3 119.9 66.0 157.8 77.7 236.3 12.8 13.7 15.3 34.9 169.2 51.4 58.6 25.3 76.6 MAML1 "KIAA0200, Mam-1" ENSG00000161021 "Mastermind like transcriptional coactivator 1" Q92585 5 179732822-179777283 "Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BJ hTERT+: 10.8;BJ hTERT+ SV40 Large T+: 11.2;hTCEpi: 11.3;SK-MEL-30: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037687, HPA057531" Approved Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA037687: AB_10672604, HPA057531: AB_2683458" "unprognostic (2.64e-1)" "unprognostic (2.06e-1)" "unprognostic (3.01e-2)" "unprognostic (5.41e-3)" "unprognostic (5.79e-2)" "unprognostic (2.45e-1)" "unprognostic (1.75e-3)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.70e-4)" "unprognostic (1.49e-1)" "unprognostic (1.59e-1)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.84e-5)" "unprognostic (3.44e-1)" "unprognostic (6.05e-2)" "unprognostic (1.06e-1)" "unprognostic (6.69e-2)" 14.6 15.8 0.4 2.5 0.6 4.9 14.0 0.6 0.8 17.2 0.4 17.7 3.3 17.8 5.1 15.3 16.9 0.0 12.2 0.3 0.3 11.1 11.0 13.9 1.6 0.5 0.4 20.2 15.2 0.0 12.7 3.0 0.4 15.7 2.6 1.5 13.4 0.0 12.5 16.5 14.7 3.7 0.3 16.2 13.9 9.7 0.4 0.0 14.4 3.7 0.0 15.8 15.4 0.5 0.0 0.0 0.0 0.0 9.3 9.1 0.0 5.9 10.8 11.2 8.1 0.0 0.0 7.1 8.2 0.0 0.0 0.3 0.0 0.0 7.1 0.0 0.0 0.0 8.7 0.0 8.2 0.0 0.1 0.0 11.3 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.7 0.2 0.1 0.0 0.0 0.2 19.8 10.1 8.9 0.0 9.0 0.1 1.4 0.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.4 0.2 0.1 0.7 0.2 0.3 0.1 0.5 0.2 0.2 0.7 0.2 0.5 0.2 0.1 0.3 0.4 0.6 0.6 0.8 0.3 0.3 0.5 0.4 0.4 0.3 0.4 0.5 15.0 16.0 9.3 11.8 14.0 25.0 12.1 12.1 20.5 12.5 13.9 15.2 7.2 15.7 7.5 9.2 18.8 10.1 20.8 12.0 1.9 6.4 2.4 10.1 15.6 26.4 9.0 16.2 18.1 6.5 12.0 11.6 13.7 13.9 56.0 14.4 33.5 9.9 13.0 21.9 18.2 11.6 12.2 24.2 26.7 2.3 17.4 16.6 5.4 9.4 19.6 7.9 13.4 18.6 14.8 6.7 6.4 25.2 14.0 12.6 7.7 3.9 6.1 9.4 13.1 11.6 14.1 6.1 10.0 19.7 29.8 9.3 17.1 9.7 12.3 16.0 MAP1LC3B2 ATG8G ENSG00000258102 "Microtubule associated protein 1 light chain 3 beta 2" A6NCE7 12 116548105-116576606 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.5;Langerhans cells: 33.4;Paneth cells: 63.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 7.2" "HPA042824, HPA052474, HPA052484, HPA053767" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Nucleoplasm "HPA042824: , HPA052474: AB_2681844, HPA052484: AB_2681846, HPA053767: AB_2682253" "unprognostic (1.50e-1)" "unprognostic (6.94e-2)" "unprognostic (9.14e-2)" "unprognostic (3.89e-3)" "unprognostic (1.62e-1)" "unprognostic (1.22e-1)" "unprognostic (2.43e-3)" "unprognostic (3.15e-1)" "unprognostic (2.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.33e-1)" "unprognostic (1.84e-1)" "unprognostic (1.11e-3)" "unprognostic (6.66e-3)" "unprognostic (1.65e-1)" "unprognostic (1.53e-2)" "unprognostic (3.42e-1)" 1.8 2.2 0.3 0.7 0.4 3.9 1.5 2.0 0.6 0.7 0.8 0.9 1.2 1.3 1.2 1.8 1.0 1.6 2.4 0.3 0.8 1.3 1.1 1.2 1.1 0.5 0.6 1.4 0.8 0.1 0.9 0.7 0.7 0.8 1.5 0.9 1.2 0.0 4.2 1.6 1.4 1.5 0.5 0.8 0.8 1.1 0.4 0.7 0.9 0.5 1.5 0.8 0.9 0.7 1.4 0.7 1.5 1.8 0.4 0.5 1.6 2.8 0.2 0.0 0.1 2.7 2.0 1.1 1.8 0.2 3.4 1.0 0.4 0.3 0.5 1.0 1.9 0.6 2.7 4.9 0.9 0.9 1.0 0.1 0.4 0.9 0.7 3.9 1.9 1.2 3.3 3.0 0.3 2.7 1.0 1.9 0.8 1.2 2.6 1.4 0.2 3.6 0.2 1.5 1.5 2.3 1.9 0.6 7.2 2.8 1.0 0.4 0.7 2.6 0.9 2.2 1.4 2.2 3.3 3.6 3.9 1.4 1.3 38.6 11.6 34.2 7.8 11.8 7.2 9.0 8.8 7.9 9.4 7.7 6.1 7.0 43.5 9.8 14.2 9.6 15.9 13.6 0.3 0.4 2.0 0.6 0.3 0.8 0.5 0.6 0.7 0.5 0.4 0.7 1.9 0.0 1.7 10.7 4.0 24.2 17.3 6.1 0.0 1.5 1.1 2.5 40.5 1.5 4.6 0.0 0.0 2.5 2.8 22.7 7.9 0.2 12.3 2.8 2.2 8.0 1.8 24.0 4.4 0.0 2.4 8.3 0.0 5.9 7.0 0.9 2.5 2.0 4.5 13.5 8.6 7.5 12.2 7.2 33.4 14.2 4.7 5.5 10.6 1.0 2.4 0.5 7.2 4.0 1.7 0.4 63.1 3.8 0.1 12.5 2.5 8.1 3.1 1.1 0.0 9.0 8.0 20.8 11.5 0.0 21.5 11.4 8.2 0.8 5.9 21.8 MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124122 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 724.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003835, HPA051993" Supported Supported Cytosol NA NA 140000 "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB003835: AB_562312, HPA051993: AB_2681685" "unprognostic (4.39e-1)" "prognostic favorable (3.72e-4)" "unprognostic (4.24e-1)" "unprognostic (1.26e-3)" "unprognostic (2.58e-1)" "prognostic favorable (7.98e-4)" "unprognostic (2.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (7.45e-3)" "unprognostic (4.95e-2)" "unprognostic (1.32e-1)" "prognostic favorable (5.43e-5)" "unprognostic (2.91e-2)" "unprognostic (2.25e-1)" "unprognostic (4.90e-2)" 73.9 118.4 145.5 54.1 143.1 102.4 69.1 151.5 190.7 76.6 150.4 103.4 134.0 72.3 23.2 121.6 64.7 30.4 156.6 145.9 147.3 82.6 123.3 66.8 57.1 149.6 152.9 84.1 134.3 54.9 99.3 36.4 154.3 93.9 42.7 68.0 79.6 37.6 289.0 95.8 101.0 31.7 143.5 89.1 92.7 131.6 150.7 69.3 74.6 132.1 41.0 77.2 75.2 142.8 163.1 175.4 93.7 132.8 127.1 151.9 93.8 104.5 138.8 139.6 125.8 153.0 85.5 137.7 95.9 120.0 111.9 114.3 74.2 111.6 107.4 118.1 90.4 50.5 91.4 171.7 194.0 93.6 101.8 168.8 106.8 98.2 129.5 185.5 125.2 123.0 98.1 263.1 119.3 203.5 186.3 130.6 107.8 118.6 125.9 140.7 61.9 159.1 123.5 102.7 126.8 126.3 95.7 130.6 344.1 107.3 101.0 158.5 111.8 113.6 98.2 293.4 163.9 263.1 172.4 100.2 176.5 166.8 199.3 27.5 13.0 45.4 16.9 16.6 13.6 13.0 13.3 17.2 15.9 18.2 12.3 15.9 21.2 18.8 14.1 9.0 14.3 7.3 145.5 143.1 151.5 190.7 145.9 147.3 149.6 152.9 154.3 143.5 150.7 142.8 77.7 9.6 31.9 22.5 62.3 35.4 93.3 21.3 15.4 85.1 92.9 95.4 62.9 44.3 22.8 40.5 41.7 28.7 102.3 300.5 146.8 20.7 248.1 59.5 68.3 52.1 63.2 123.1 17.6 45.5 38.6 60.3 64.7 48.8 19.7 124.4 49.2 48.1 55.0 121.1 23.2 107.7 16.2 56.0 38.2 724.3 35.8 65.6 42.7 10.3 28.5 121.1 62.8 13.0 24.2 47.0 151.8 23.0 79.9 103.2 166.1 92.8 18.9 106.8 26.3 93.1 71.8 23.5 17.4 42.9 63.9 35.6 77.0 120.2 119.9 113.1 MAP2K5 "HsT17454, MAPKK5, MEK5, PRKMK5" ENSG00000137764 "Mitogen-activated protein kinase kinase 5" Q13163 15 67542703-67807117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Astrocytes: 119.5;Early spermatids: 138.1;Excitatory neurons: 201.4;Inhibitory neurons: 169.3;Late spermatids: 212.4;Microglial cells: 87.1;Oligodendrocyte precursor cells: 146.3;Oligodendrocytes: 146.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022094, HPA027347, HPA027755" Supported Approved Nucleoli,Microtubules NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Microtubules" "CAB022094: , HPA027347: AB_10599290, HPA027755: AB_10600883" "unprognostic (4.54e-2)" "unprognostic (1.87e-2)" "unprognostic (4.16e-2)" "unprognostic (9.06e-2)" "unprognostic (1.77e-3)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" "unprognostic (3.73e-1)" "unprognostic (2.41e-2)" "unprognostic (2.83e-1)" "unprognostic (1.47e-2)" "unprognostic (5.41e-2)" "prognostic favorable (8.03e-5)" "unprognostic (1.68e-1)" "unprognostic (2.74e-1)" "unprognostic (3.99e-2)" "unprognostic (2.73e-2)" 14.3 14.8 9.2 6.3 9.8 10.3 12.4 11.2 14.1 13.2 4.6 15.7 9.2 11.5 6.1 8.7 12.1 8.8 15.0 11.6 9.9 9.9 10.0 9.7 8.5 9.6 6.5 17.2 13.2 18.8 10.2 11.1 9.4 9.4 8.8 11.2 10.5 10.6 23.2 14.5 10.1 8.9 5.6 9.0 11.6 13.8 7.3 17.2 10.6 17.8 7.6 11.8 11.1 12.3 9.0 23.4 13.8 16.3 20.0 34.9 10.9 8.8 17.8 16.3 17.7 9.4 15.8 14.8 18.2 14.8 17.7 13.3 23.8 14.3 13.4 21.6 23.7 20.2 17.0 10.3 25.1 12.3 12.1 23.9 18.3 11.8 26.6 35.7 21.7 33.6 18.0 24.1 13.6 11.6 20.1 14.7 19.4 10.4 11.3 19.7 16.0 24.9 9.8 16.3 8.6 13.4 9.9 14.5 36.5 23.6 18.2 23.7 18.2 16.7 10.9 11.7 12.1 33.7 43.4 17.5 22.4 27.6 12.3 10.9 5.8 5.6 5.6 4.4 8.3 4.8 5.3 6.7 8.1 4.3 7.3 7.0 1.4 9.4 5.4 3.0 6.2 4.4 9.2 9.8 11.2 14.1 11.6 9.9 9.6 6.5 9.4 5.6 7.3 12.3 7.9 6.4 5.8 119.5 10.0 6.9 8.1 3.7 8.6 12.6 8.6 6.1 8.1 5.7 3.2 5.5 10.4 13.4 10.2 13.2 7.9 9.3 138.1 4.4 5.0 7.6 9.5 9.4 201.4 8.5 10.7 9.7 7.7 3.9 2.5 12.3 12.5 8.7 10.0 5.0 169.3 9.2 4.1 10.1 6.1 212.4 12.5 7.9 10.6 87.1 7.2 17.9 11.3 146.3 146.5 7.5 12.5 11.7 5.6 5.3 12.2 9.7 4.0 8.2 0.0 7.9 6.3 11.9 13.0 9.9 8.2 9.9 10.4 11.6 10.4 4.6 MAP3K11 "MEKK11, MLK3, PTK1, SPRK" ENSG00000173327 "Mitogen-activated protein kinase kinase kinase 11" Q16584 11 65597756-65615382 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010165 Approved Supported "Centriolar satellite,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite, Cytosol" "CAB010165: AB_631936" "unprognostic (8.36e-2)" "unprognostic (1.17e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (3.40e-1)" "unprognostic (1.87e-1)" "unprognostic (7.56e-3)" "unprognostic (3.10e-2)" "unprognostic (4.50e-2)" "unprognostic (4.30e-1)" "unprognostic (4.69e-2)" "unprognostic (2.77e-2)" "unprognostic (3.13e-2)" "unprognostic (2.01e-2)" "unprognostic (7.62e-2)" "unprognostic (1.95e-1)" "unprognostic (8.27e-3)" 47.6 32.6 39.9 36.9 51.7 24.4 42.9 45.1 48.4 27.2 27.2 40.0 48.3 29.7 7.4 35.6 31.3 13.5 53.2 36.1 38.8 48.5 95.3 62.7 23.7 48.8 50.3 21.0 35.8 12.1 27.8 21.6 44.6 39.2 11.7 2.8 29.1 12.6 20.1 35.9 51.0 10.0 41.5 78.3 36.3 21.3 50.5 19.3 37.3 10.4 11.3 29.2 28.3 60.1 48.0 43.4 23.1 22.6 7.0 8.0 21.7 19.3 11.9 19.9 14.9 43.4 43.9 16.4 65.5 13.0 33.0 40.9 12.2 19.5 7.1 40.2 15.5 50.0 28.2 50.9 18.6 28.9 71.2 12.4 19.1 14.5 13.3 21.6 57.4 21.5 21.6 32.7 10.9 58.2 34.0 50.9 24.2 31.0 48.1 56.1 13.3 36.2 19.2 43.1 19.6 22.9 22.0 58.1 107.7 10.4 46.6 45.8 68.8 31.3 35.8 48.1 32.4 23.3 27.5 15.8 35.3 33.1 75.1 7.5 10.5 13.1 3.1 15.3 3.0 2.7 3.2 4.5 10.1 3.0 2.4 1.8 17.3 2.4 15.4 3.0 1.8 9.5 39.9 51.7 45.1 48.4 36.1 38.8 48.8 50.3 44.6 41.5 50.5 60.1 70.0 22.4 21.1 4.2 22.1 21.0 25.3 18.4 20.5 24.4 28.9 23.4 8.7 31.5 14.1 11.0 25.0 24.7 26.4 123.5 19.6 21.9 13.5 15.4 11.3 78.9 41.9 13.0 4.1 27.5 17.7 11.4 44.4 26.1 26.0 19.6 58.5 56.2 53.3 18.5 3.5 54.9 20.3 50.6 65.5 68.5 9.6 48.3 21.4 21.5 50.2 16.1 23.7 3.0 29.5 33.7 99.0 6.4 15.5 28.1 113.1 27.6 10.3 54.7 32.9 10.5 12.8 12.2 18.3 24.8 30.0 34.3 24.0 28.9 55.2 34.6 MAP4K3 "GLK, MAPKKKK3, RAB8IPL1" ENSG00000011566 "Mitogen-activated protein kinase kinase kinase kinase 3" Q8IVH8 2 39249266-39437301 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 118.8;Excitatory neurons: 201.0;Inhibitory neurons: 198.3;Microglial cells: 144.3;Oligodendrocyte precursor cells: 160.4;Oligodendrocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "AF22: 102.3;RT4: 97.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030380 Approved Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" Nucleoplasm "HPA030380: AB_10601132" "unprognostic (4.82e-2)" "unprognostic (7.22e-2)" "unprognostic (5.87e-3)" "unprognostic (7.34e-3)" "unprognostic (6.77e-2)" "unprognostic (2.57e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.66e-1)" "unprognostic (6.73e-2)" "unprognostic (4.33e-3)" "unprognostic (4.26e-2)" "unprognostic (2.12e-1)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (2.43e-1)" "unprognostic (5.08e-2)" 15.8 17.1 11.6 6.7 12.5 10.5 16.6 21.6 16.7 15.0 15.3 15.5 13.2 17.2 13.4 10.2 13.6 14.7 19.3 14.2 11.2 24.5 15.1 13.3 6.1 9.9 10.0 20.2 12.2 25.3 12.2 27.4 10.0 16.9 13.0 28.0 10.8 14.0 30.9 16.4 14.3 14.5 11.3 11.6 26.6 21.3 10.2 8.1 24.4 22.2 6.1 18.3 11.4 14.4 25.6 15.6 102.3 16.3 16.3 32.4 28.0 22.1 28.3 21.6 18.3 13.3 12.6 5.5 24.3 15.3 22.1 13.6 39.0 19.7 32.6 6.3 16.0 9.2 10.8 30.9 42.3 4.0 14.5 29.3 19.0 28.1 30.1 22.6 18.8 5.0 12.1 9.9 29.2 13.9 9.0 6.0 30.7 24.0 23.4 9.9 33.3 4.2 28.3 97.3 18.2 20.7 12.9 20.7 58.8 32.0 13.9 5.6 15.4 16.7 19.7 15.0 12.1 15.1 9.3 1.9 20.5 6.6 19.0 0.7 0.1 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.4 0.1 0.1 0.0 11.6 12.5 21.6 16.7 14.2 11.2 9.9 10.0 10.0 11.3 10.2 14.4 36.2 3.2 8.4 118.8 8.1 17.6 17.9 11.0 16.5 24.7 14.1 12.3 38.2 21.5 16.5 22.0 25.0 13.1 4.1 12.5 19.6 10.3 45.1 22.3 19.9 20.6 9.6 4.6 201.0 12.4 6.7 18.2 25.5 59.4 2.5 15.6 14.3 18.6 9.7 6.7 198.3 13.9 2.0 10.9 20.6 103.0 20.8 14.4 5.4 144.3 4.4 13.2 3.1 160.4 129.2 17.5 5.7 17.7 14.3 18.6 14.0 11.9 19.5 37.9 19.7 18.7 17.6 22.6 19.8 11.8 19.2 10.4 5.9 17.4 10.6 30.2 MBNL2 "MBLL, MBLL39" ENSG00000139793 "Muscleblind like splicing regulator 2" Q5VZF2 13 97221434-97394120 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 325.5;Oligodendrocytes: 702.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062685 Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA062685: AB_2684834" "unprognostic (8.02e-2)" "unprognostic (7.78e-2)" "unprognostic (6.37e-2)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.58e-1)" "unprognostic (3.54e-1)" "unprognostic (1.44e-3)" "unprognostic (1.08e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.00e-1)" "unprognostic (5.26e-3)" "unprognostic (1.01e-2)" "unprognostic (1.48e-1)" "unprognostic (2.73e-1)" "unprognostic (9.17e-2)" 64.4 64.6 34.6 20.7 52.0 8.5 35.1 51.4 58.5 38.7 18.3 31.8 21.1 35.0 16.0 38.2 21.7 44.8 36.8 32.9 38.6 36.9 94.9 29.6 20.8 47.5 46.6 59.3 46.4 25.8 23.8 52.6 49.0 31.9 24.5 50.1 41.4 38.4 41.6 18.9 19.1 41.5 45.2 19.8 30.5 14.4 42.2 24.2 36.6 87.9 24.2 34.9 24.5 80.6 34.7 12.1 13.5 13.7 68.9 36.1 1.3 77.8 38.4 34.8 35.3 14.8 49.8 11.7 31.4 106.3 39.5 48.6 6.1 34.1 44.6 31.2 5.9 14.2 26.4 34.7 101.7 1.6 12.4 37.9 56.7 28.6 54.7 39.5 67.4 15.5 18.1 6.0 17.6 9.2 8.2 4.9 0.4 4.2 20.2 3.8 27.9 9.8 46.2 41.1 17.3 28.7 45.0 44.6 76.2 30.3 18.9 2.0 21.1 5.2 16.1 9.7 16.2 16.0 4.3 3.1 33.1 4.0 93.2 15.0 5.4 8.0 8.1 7.1 10.3 7.6 7.3 7.4 5.7 6.2 6.3 8.6 0.8 4.9 5.4 4.7 8.3 6.2 34.6 52.0 51.4 58.5 32.9 38.6 47.5 46.6 49.0 45.2 42.2 80.6 153.8 83.3 45.1 148.9 52.3 70.2 27.4 15.7 129.1 23.7 50.7 49.9 69.8 50.1 40.1 29.5 47.9 25.3 31.6 22.6 19.6 26.6 3.1 59.1 113.8 66.6 48.6 24.8 325.5 42.7 78.0 75.7 83.6 50.0 17.7 40.5 45.3 78.8 14.4 47.1 108.3 29.0 8.2 32.1 30.6 9.1 70.5 31.2 56.9 144.3 19.5 84.8 18.6 144.3 702.4 54.0 14.5 44.8 169.1 22.3 16.3 40.1 54.5 112.6 46.0 29.9 80.8 1.1 1.0 54.2 48.6 25.0 40.8 28.2 17.9 30.3 MBP ENSG00000197971 "Myelin basic protein" P02686 18 76978827-77133683 "Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Autoimmune encephalomyelitis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 142 "brain: 30812.9;choroid plexus: 9144.9" "Cell type enriched" "Detected in many" 11 "Oligodendrocytes: 2895.5" "Group enriched" "Detected in all" 9 "glioma: 47.5;melanoma: 20.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 99.3;SK-MEL-30: 204.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002300, HPA049222, HPA064368" Enhanced Supported Approved "Plasma membrane" NA NA 54000 "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB002300: AB_563893, HPA049222: AB_2680679, HPA064368: AB_2685247" "unprognostic (9.36e-2)" "unprognostic (7.60e-2)" "unprognostic (1.28e-2)" "unprognostic (1.22e-1)" "unprognostic (6.93e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (3.31e-1)" "unprognostic (9.87e-2)" "unprognostic (2.90e-2)" "unprognostic (5.25e-2)" "unprognostic (1.95e-1)" "prognostic favorable (4.48e-12)" "unprognostic (2.90e-1)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (6.03e-2)" 27.3 7.1 15448.6 20.9 21296.6 43.0 20.9 19749.8 26916.8 17.3 9144.9 19.0 18.6 13.2 7.9 20.5 31.5 17.2 24.1 12696.6 16271.8 28.7 23.5 20.0 26.9 30812.9 22193.8 22.3 22.8 47.5 26.7 4.7 25986.2 15.3 16.9 7.5 22.0 13.0 140.8 28.7 20.7 8.7 23219.4 28.0 17.5 6.1 19406.0 12.5 22.2 81.6 27.8 19.0 20.2 30044.2 26.1 22.4 0.2 0.8 35.8 53.1 8.5 0.6 0.6 0.8 0.6 3.2 39.2 15.9 4.4 1.7 0.2 49.9 3.8 22.1 0.7 60.7 5.3 10.4 3.9 5.2 22.5 99.3 65.3 7.7 18.4 19.8 30.3 16.4 6.5 37.9 0.0 3.6 0.0 3.2 4.1 50.6 2.2 15.6 18.1 1.5 0.4 35.9 34.5 34.3 1.8 0.3 3.2 0.0 204.7 6.1 0.6 60.5 0.1 0.2 0.5 0.2 2.8 0.1 0.5 16.9 5.8 62.0 2.5 21.7 8.5 32.4 21.6 8.1 13.1 5.9 15.4 28.1 9.2 5.1 9.1 17.0 39.5 28.0 8.1 11.9 14.9 11.6 15448.6 21296.6 19749.8 26916.8 12696.6 16271.8 30812.9 22193.8 25986.2 23219.4 19406.0 30044.2 5.5 48.1 39.5 10.7 86.8 118.8 61.1 28.1 84.2 52.8 24.2 22.7 45.0 35.8 50.3 103.0 2.1 0.7 221.8 48.7 41.1 43.7 5.9 159.8 11.2 9.4 49.8 68.8 32.4 35.8 0.8 36.2 59.1 161.1 71.5 2.1 10.0 30.2 44.4 1.7 47.1 51.4 44.7 78.3 123.1 6.3 28.3 98.2 92.5 45.0 84.4 25.7 247.2 124.7 2895.5 60.4 25.5 14.3 45.3 117.6 37.5 36.0 54.0 6.1 0.0 88.7 8.4 7.7 1.1 75.6 154.7 0.7 151.6 0.0 42.1 103.7 MC1R MSH-R ENSG00000258839 "Melanocortin 1 receptor" Q01726 16 89912119-89920973 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 27.9;testis: 29.0" "Cell type enhanced" "Detected in many" "granulocytes: 17.2;Melanocytes: 17.8;Spermatocytes: 10.6" "Cancer enriched" "Detected in many" 5 "melanoma: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 23.0;SK-MEL-30: 47.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 60: Granulocytes - Receptor signaling" "unprognostic (3.90e-2)" "unprognostic (9.05e-2)" "unprognostic (5.39e-7)" "unprognostic (5.00e-2)" "unprognostic (1.39e-1)" "unprognostic (1.30e-1)" "unprognostic (1.00e-2)" "unprognostic (1.73e-1)" "unprognostic (1.55e-2)" "unprognostic (8.26e-2)" "prognostic favorable (7.88e-4)" "unprognostic (1.02e-2)" "unprognostic (5.20e-3)" "unprognostic (4.25e-2)" "unprognostic (5.17e-2)" "unprognostic (2.58e-2)" "unprognostic (1.16e-2)" 3.6 4.4 6.5 2.1 7.6 1.0 3.3 10.4 8.2 7.8 4.8 6.4 1.9 5.1 2.6 2.6 8.7 3.0 4.4 6.3 8.1 8.3 2.6 4.1 1.9 6.8 6.3 7.9 3.5 0.6 27.9 3.1 6.9 9.9 0.9 3.1 5.1 1.8 1.2 7.2 5.2 2.1 5.9 4.4 3.8 29.0 7.4 1.0 15.7 0.2 0.9 6.2 4.7 6.4 3.3 14.6 2.4 3.8 2.4 4.5 3.3 4.4 3.9 3.2 2.0 3.9 3.6 2.8 6.2 4.7 1.6 7.4 1.5 1.1 1.2 1.6 4.2 0.6 5.8 11.0 0.6 0.8 3.3 6.5 2.0 4.3 1.3 2.8 2.8 0.9 3.1 3.5 2.2 23.0 0.1 20.9 3.0 3.6 2.8 1.7 3.1 2.6 2.7 1.8 4.8 2.5 4.9 1.8 47.6 1.5 20.3 3.3 1.9 4.6 9.8 2.2 1.6 14.0 8.5 1.3 5.9 10.1 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.5 7.6 10.4 8.2 6.3 8.1 6.8 6.3 6.9 5.9 7.4 6.4 1.0 3.2 1.7 2.3 1.0 2.3 0.8 1.2 0.0 7.1 2.4 1.3 0.9 1.5 1.6 1.8 8.4 1.3 1.6 2.0 0.0 0.9 1.0 2.2 2.8 1.5 4.2 0.4 2.2 1.8 2.3 2.0 5.1 2.8 17.2 0.7 2.9 2.2 0.8 6.7 2.3 2.3 2.0 0.6 1.0 1.0 0.6 1.1 17.8 1.0 0.2 2.0 2.1 2.0 1.0 1.2 1.5 0.4 0.8 1.5 2.1 0.3 1.9 2.6 0.0 1.6 1.7 10.6 2.8 1.2 2.4 4.5 1.2 0.6 1.9 0.9 MCMDC2 "C8orf45, FLJ25692" ENSG00000178460 "Minichromosome maintenance domain containing 2" Q4G0Z9 8 66870749-66922048 "Predicted intracellular proteins" "DNA damage, DNA repair, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.9" "Group enriched" "Detected in many" 4 "Early spermatids: 50.7;Spermatocytes: 65.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-MEL-30: 12.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA026522 Approved "Actin filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Actin filaments" "HPA026522: AB_10603453" "unprognostic (6.97e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (2.85e-2)" "unprognostic (6.16e-3)" "unprognostic (5.54e-2)" "unprognostic (2.38e-2)" "unprognostic (3.03e-1)" "unprognostic (1.42e-1)" "unprognostic (9.46e-2)" "unprognostic (9.89e-2)" "unprognostic (4.04e-1)" "unprognostic (6.79e-3)" "unprognostic (7.87e-2)" "unprognostic (3.06e-2)" "unprognostic (8.49e-2)" "unprognostic (2.31e-5)" 1.1 1.8 0.5 1.3 1.1 4.1 0.7 2.0 0.9 0.4 0.0 0.7 1.4 1.2 0.9 1.6 1.0 1.1 2.5 0.4 0.7 1.0 0.6 0.8 2.8 1.0 0.8 3.0 1.5 1.1 0.9 0.5 0.9 0.9 0.7 4.4 1.4 0.3 5.9 2.2 1.4 0.1 0.7 1.2 1.0 11.9 0.7 0.2 1.4 1.4 0.2 0.7 0.3 1.9 2.7 5.6 2.8 3.4 0.4 1.3 1.5 2.5 0.4 0.2 0.2 4.8 3.5 4.1 1.0 0.2 1.5 2.3 0.0 0.1 0.8 2.1 6.9 5.1 8.9 5.8 0.6 2.3 2.7 0.9 0.8 0.1 0.0 4.1 0.2 3.9 3.2 3.8 1.1 5.3 5.8 7.2 3.5 4.5 5.1 2.0 1.0 1.8 0.5 4.1 1.9 3.5 0.8 1.0 12.3 1.6 3.5 6.0 1.2 1.9 2.7 3.2 3.1 3.1 1.8 3.9 2.1 4.8 2.0 0.9 0.5 0.2 0.9 0.4 1.2 1.0 1.4 1.1 1.1 1.0 1.6 1.4 0.2 1.3 0.3 1.2 1.1 0.5 0.5 1.1 2.0 0.9 0.4 0.7 1.0 0.8 0.9 0.7 0.7 1.9 0.4 0.0 0.5 12.4 0.7 0.4 0.5 0.4 1.2 2.0 1.8 1.3 2.7 0.0 0.4 1.8 6.2 1.2 0.2 0.4 0.0 0.2 50.7 4.9 0.9 0.7 0.0 0.0 6.2 0.2 0.6 0.5 2.6 0.6 0.0 0.7 0.4 0.0 0.5 1.7 5.1 0.8 0.0 1.6 0.3 12.4 1.8 0.4 1.8 0.0 0.0 2.0 1.0 6.0 12.0 0.1 0.3 0.7 0.2 0.2 0.2 0.8 3.6 2.4 0.0 1.0 0.6 65.7 11.1 1.3 1.0 0.0 0.7 1.2 1.2 0.6 MCOLN3 "FLJ11006, TRP-ML3, TRPML3" ENSG00000055732 "Mucolipin 3" Q8TDD5 1 85018082-85048500 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 43.5;epididymis: 13.9;parathyroid gland: 35.3" "Group enriched" "Detected in many" 7 "Enteroendocrine cells: 113.6;Melanocytes: 151.2" "Cancer enriched" "Detected in many" 6 "melanoma: 8.0" "Group enriched" "Detected in some" 5 "cerebral cortex: 4.0;hippocampal formation: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 12.9;HAP1: 12.7;RH-30: 15.7;SK-MEL-30: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018106, HPA062137" Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "HPA018106: AB_1853647, HPA062137: AB_2684695" "unprognostic (5.91e-2)" "unprognostic (1.24e-1)" "unprognostic (1.49e-2)" "unprognostic (3.21e-5)" "unprognostic (2.25e-1)" "unprognostic (8.80e-3)" "unprognostic (3.97e-3)" "unprognostic (1.13e-1)" "unprognostic (2.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.45e-3)" "unprognostic (3.09e-2)" "unprognostic (7.32e-5)" "unprognostic (6.36e-3)" "unprognostic (2.61e-1)" "unprognostic (6.11e-2)" "unprognostic (6.43e-2)" 3.0 43.5 0.7 0.2 0.2 0.0 2.2 0.0 4.0 5.1 3.3 1.0 5.4 5.7 13.9 0.3 1.7 0.3 4.4 3.5 0.1 5.0 0.1 4.5 0.1 0.0 0.1 2.1 7.4 35.3 7.0 2.5 0.1 0.3 1.0 0.1 3.7 0.6 0.2 4.3 2.2 1.9 0.2 0.9 2.6 0.6 0.5 4.3 1.9 1.1 0.2 0.4 2.4 0.0 9.0 2.0 0.0 0.0 6.6 5.9 2.4 0.1 12.9 3.2 8.8 0.6 1.5 0.0 0.9 0.1 3.0 0.0 12.7 4.2 2.0 3.6 8.6 0.0 0.7 0.0 0.0 0.0 0.0 0.6 1.5 2.6 1.5 3.2 0.0 0.0 0.0 0.0 6.3 0.7 0.0 0.0 1.0 0.0 1.1 0.0 15.7 0.0 0.4 0.0 0.5 0.0 0.4 0.0 29.3 0.9 5.2 6.5 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.0 4.0 3.5 0.1 0.0 0.1 0.1 0.2 0.5 0.0 16.6 16.0 1.7 0.0 0.0 8.7 3.5 7.0 0.6 0.0 4.2 1.9 6.8 11.5 2.5 3.7 0.0 9.0 0.1 0.3 0.0 1.7 0.4 0.8 8.1 2.0 113.6 0.0 1.2 9.6 0.2 18.4 1.5 1.9 0.0 0.3 0.0 0.1 3.5 0.0 0.4 2.5 6.1 0.0 7.1 0.1 1.8 3.2 151.2 2.8 1.6 0.0 0.0 0.0 0.1 3.6 12.9 0.0 0.3 1.4 4.1 3.4 0.7 0.0 6.6 6.3 1.2 1.8 4.1 0.4 3.4 2.6 1.4 1.0 3.8 0.6 MEF2A "RSRFC4, RSRFC9" ENSG00000068305 "Myocyte enhancer factor 2A" Q02078 15 99565417-99716466 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 262.8;Microglial cells: 708.3;Oligodendrocytes: 264.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004499, HPA046597" Approved Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004499: AB_627921, HPA046597: AB_2679714" "unprognostic (1.89e-1)" "unprognostic (8.82e-2)" "unprognostic (5.91e-2)" "unprognostic (8.04e-2)" "unprognostic (8.68e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-1)" "unprognostic (6.26e-2)" "unprognostic (1.93e-2)" "unprognostic (1.91e-2)" "unprognostic (7.08e-3)" "unprognostic (1.46e-1)" "prognostic favorable (6.93e-4)" "prognostic unfavorable (7.96e-4)" "unprognostic (4.69e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-3)" 32.8 22.9 18.7 20.3 25.4 18.3 22.1 16.4 27.6 27.7 12.9 23.5 12.8 34.5 23.8 21.7 21.8 22.6 89.7 21.9 12.1 24.8 24.5 30.4 25.0 17.4 20.7 30.1 12.8 37.6 9.8 26.4 15.4 23.0 15.0 24.2 19.5 23.7 61.5 54.8 17.6 35.7 18.4 27.2 17.8 15.0 28.4 23.3 19.7 81.9 22.9 22.5 16.6 25.7 17.9 10.1 16.7 8.5 20.7 26.3 8.2 17.8 40.8 14.4 19.5 10.4 24.4 22.3 24.5 38.6 22.1 19.3 17.1 14.1 18.6 15.3 24.8 45.2 22.3 9.4 35.4 18.1 21.3 17.6 23.2 19.3 39.7 59.6 26.5 18.3 16.3 41.6 27.0 7.4 29.7 26.3 8.9 11.9 14.6 43.3 36.1 18.5 29.5 24.9 10.7 14.8 27.2 11.6 51.0 17.6 11.0 16.4 43.7 39.8 21.9 19.9 21.7 22.6 27.8 48.5 27.8 19.6 38.7 7.7 12.1 14.3 3.9 15.6 3.3 15.8 3.6 3.6 13.3 12.1 5.0 3.9 10.8 6.5 19.3 7.8 2.6 5.6 18.7 25.4 16.4 27.6 21.9 12.1 17.4 20.7 15.4 18.4 28.4 25.7 152.7 80.1 43.9 113.9 87.2 88.6 31.7 26.9 62.0 52.0 31.6 37.0 175.8 20.0 40.7 29.5 50.1 7.7 32.9 26.5 25.4 18.0 10.4 80.3 60.6 100.6 12.7 24.8 262.8 18.8 3.4 61.5 34.7 130.7 31.0 30.5 50.3 41.0 39.5 30.3 174.9 17.2 12.2 107.5 63.1 7.8 55.9 104.1 35.6 708.3 65.8 25.2 23.7 157.3 264.4 26.8 22.6 64.7 55.6 27.0 18.9 19.7 51.7 44.9 72.3 62.4 69.4 29.9 29.6 29.4 50.4 9.2 27.8 28.8 17.9 26.8 MELTF "CD228, FLJ38863, MAP97, MFI2, MGC4856, MTf, MTF1" ENSG00000163975 Melanotransferrin P08582 3 196988621-197029817 "CD markers, Plasma proteins, Predicted intracellular proteins" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 35.1;salivary gland: 68.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 21.1;Breast myoepithelial cells: 20.6;Collecting duct cells: 14.7;Ductal cells: 28.3;Hofbauer cells: 15.4;Pancreatic endocrine cells: 66.4" "Cancer enhanced" "Detected in all" "melanoma: 32.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 162.1;SK-MEL-30: 201.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA004880 Approved "Intracellular and membrane" NA NA 41000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA004880: AB_1853844" "unprognostic (8.68e-3)" "unprognostic (3.68e-2)" "unprognostic (1.75e-2)" "unprognostic (7.68e-3)" "unprognostic (1.06e-2)" "unprognostic (1.08e-2)" "unprognostic (5.53e-2)" "unprognostic (1.64e-3)" "unprognostic (1.20e-2)" "unprognostic (1.23e-1)" "unprognostic (3.68e-3)" "unprognostic (8.14e-2)" "prognostic unfavorable (6.99e-11)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "unprognostic (5.75e-2)" "unprognostic (2.09e-2)" 10.0 1.7 2.3 3.8 1.7 2.3 7.4 2.1 3.8 8.1 27.2 4.0 2.4 6.8 0.7 2.9 8.6 1.6 7.5 2.5 1.9 35.1 1.6 1.9 1.9 0.6 2.8 1.2 4.6 10.3 2.9 1.5 0.4 4.1 2.1 0.3 68.7 5.5 1.1 16.4 9.9 1.2 0.5 1.1 1.7 3.4 6.5 2.9 3.1 1.0 1.6 3.2 7.3 2.0 162.1 34.6 0.4 1.2 4.8 6.0 4.0 2.8 1.5 5.2 6.3 9.8 23.6 4.5 33.3 5.6 4.5 49.6 1.8 0.1 2.3 7.4 10.8 5.6 7.9 4.1 30.5 0.8 30.8 33.0 4.3 4.3 0.4 0.2 0.8 8.9 4.3 30.5 3.1 9.8 9.3 0.0 3.6 6.9 22.5 13.4 5.3 2.0 0.8 1.5 3.1 11.3 32.5 2.8 201.4 3.8 9.5 4.8 1.2 1.2 26.8 5.5 19.9 5.3 46.0 4.5 3.9 9.5 0.2 0.0 0.1 0.0 0.2 0.2 0.8 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.2 2.3 1.7 2.1 3.8 2.5 1.9 0.6 2.8 0.4 0.5 6.5 2.0 0.8 0.0 1.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 21.1 20.6 0.0 0.0 1.8 14.7 0.0 0.2 1.0 0.0 0.0 28.3 0.0 3.2 6.1 0.6 0.0 0.0 0.0 5.7 0.3 3.7 0.0 4.4 0.0 3.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 2.6 0.0 0.0 0.0 0.0 66.4 0.0 0.0 1.7 0.0 0.0 0.5 1.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.0 MESD "BOCA, KIAA0081, MESDC2" ENSG00000117899 "Mesoderm development LRP chaperone" Q14696 15 80946289-80989828 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" Chaperone "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 341.4;Extravillous trophoblasts: 279.3;Syncytiotrophoblasts: 436.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039414, HPA041721" Approved Supported "Nuclear bodies,Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 1600000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "Nuclear bodies, Cytosol" "HPA039414: AB_10674981, HPA041721: AB_2756310" "unprognostic (9.21e-2)" "unprognostic (4.50e-2)" "unprognostic (8.02e-2)" "prognostic favorable (2.31e-4)" "unprognostic (4.93e-3)" "unprognostic (2.32e-3)" "unprognostic (3.47e-2)" "unprognostic (3.09e-3)" "unprognostic (4.04e-1)" "prognostic favorable (1.12e-4)" "unprognostic (7.93e-2)" "unprognostic (3.05e-2)" "unprognostic (3.42e-2)" "unprognostic (1.68e-1)" "unprognostic (4.32e-2)" "unprognostic (3.83e-1)" "unprognostic (1.88e-1)" 14.4 17.4 11.9 13.7 13.6 5.4 13.9 13.7 13.0 17.8 14.6 14.6 12.8 11.3 42.7 14.6 12.4 11.5 12.8 11.7 14.2 14.4 20.6 14.1 14.0 13.4 13.1 17.4 19.2 14.0 17.8 26.9 13.8 18.2 14.5 10.4 18.4 14.3 7.7 10.9 12.7 11.1 13.4 13.8 15.3 9.8 13.8 14.2 33.7 10.6 13.2 15.4 14.4 15.0 26.8 40.2 34.6 22.3 57.1 32.4 54.0 40.0 47.4 42.7 51.6 36.0 72.9 22.4 45.4 32.3 45.1 43.8 54.1 41.1 40.3 50.2 35.5 28.3 33.0 61.9 43.7 33.8 30.0 33.9 46.6 36.1 42.4 35.7 41.1 27.0 34.7 55.5 36.7 34.0 20.9 28.3 41.9 39.3 16.4 31.7 21.3 59.7 35.6 36.3 29.9 17.6 43.9 29.3 70.0 62.4 34.0 26.8 32.4 40.9 39.1 22.1 52.2 35.0 48.0 30.2 38.5 59.7 43.8 39.4 26.1 19.1 35.6 24.9 41.8 34.5 37.2 35.4 27.2 35.4 34.6 34.7 8.1 44.8 22.5 45.2 42.5 31.1 11.9 13.6 13.7 13.0 11.7 14.2 13.4 13.1 13.8 13.4 13.8 15.0 59.7 80.1 59.6 0.0 20.6 0.0 0.0 0.0 0.0 0.0 51.0 44.2 0.0 0.0 27.9 58.8 0.0 341.4 41.6 0.0 13.7 100.9 0.0 41.4 79.4 36.9 0.0 0.0 0.0 111.9 279.3 48.4 0.0 69.8 36.6 56.4 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.0 0.0 0.0 86.3 0.0 0.0 0.0 0.0 82.5 0.0 0.0 18.8 0.0 0.0 48.8 43.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.0 436.0 25.8 63.6 0.0 0.0 METTL23 "C17orf95, LOC124512" ENSG00000181038 "Methyltransferase like 23" Q86XA0 17 76726830-76733936 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 182.5;Spermatocytes: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022889 Approved Vesicles No No "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA022889: " "unprognostic (5.45e-3)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.35e-1)" "unprognostic (7.70e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (4.18e-6)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (1.73e-2)" "unprognostic (1.03e-3)" "unprognostic (3.21e-2)" "prognostic unfavorable (3.93e-7)" "unprognostic (1.13e-2)" "unprognostic (1.82e-1)" "unprognostic (3.79e-1)" "unprognostic (3.65e-1)" 30.8 32.7 20.4 24.2 22.8 27.3 30.6 22.5 27.9 28.7 24.2 26.0 22.6 25.8 34.7 23.9 27.7 19.8 28.5 20.1 21.4 39.1 47.3 26.7 42.7 21.9 22.0 29.4 42.2 35.1 33.3 19.7 22.7 28.1 27.4 22.9 29.1 21.9 34.7 29.2 30.7 23.5 22.3 48.1 30.0 51.6 21.9 36.9 42.1 25.9 40.4 26.1 24.7 26.1 68.3 58.4 32.6 30.0 79.2 66.5 31.3 33.7 68.2 43.5 41.9 29.5 47.1 38.0 32.2 43.0 56.7 37.6 23.8 61.0 48.9 19.2 55.8 49.5 38.0 56.6 77.4 35.1 41.7 64.0 57.3 54.0 74.6 68.5 69.1 46.5 48.1 46.0 53.1 38.5 44.3 30.1 24.2 75.2 65.3 29.9 54.5 106.5 63.0 33.9 30.9 44.5 33.8 51.6 123.3 78.8 72.3 43.7 25.8 49.8 24.9 48.9 59.9 63.2 26.0 38.6 47.5 25.0 46.3 23.0 28.9 34.1 48.0 30.3 53.6 51.3 53.0 53.5 32.1 44.7 50.2 51.1 9.4 51.8 27.9 48.3 57.6 34.5 20.4 22.8 22.5 27.9 20.1 21.4 21.9 22.0 22.7 22.3 21.9 26.1 39.5 28.9 14.5 8.5 49.6 16.4 47.2 64.8 42.1 13.9 34.9 48.4 17.7 27.1 35.6 20.2 10.4 42.9 50.7 11.7 119.3 42.0 182.5 31.7 23.4 28.0 22.8 22.3 4.2 39.5 41.1 26.6 24.5 25.9 31.1 21.8 25.7 49.9 57.0 6.7 5.4 24.5 40.7 33.3 23.5 54.5 32.6 33.9 24.9 8.4 50.1 38.6 81.4 7.5 13.4 33.2 26.3 25.9 49.2 33.2 27.5 87.8 32.7 23.7 52.6 28.1 43.0 198.9 49.5 32.2 16.2 17.2 55.3 53.3 32.1 34.1 METTL9 DREV1 ENSG00000197006 "Methyltransferase like 9" Q9H1A3 16 21597218-21657473 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 414.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053588, HPA056347" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cell Junctions" Cytosol "HPA053588: AB_2682203, HPA056347: " "unprognostic (1.55e-1)" "unprognostic (2.18e-2)" "unprognostic (1.98e-3)" "unprognostic (5.43e-2)" "unprognostic (5.81e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (8.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.11e-2)" "unprognostic (7.57e-3)" "unprognostic (1.73e-2)" "unprognostic (3.18e-1)" "unprognostic (1.49e-3)" "unprognostic (2.14e-1)" "unprognostic (3.28e-1)" "unprognostic (5.17e-2)" "unprognostic (1.65e-1)" 63.6 100.6 41.9 31.1 52.7 118.7 54.5 39.5 53.2 62.9 53.1 45.2 28.3 46.3 70.5 67.8 42.4 32.9 42.0 44.9 41.7 140.8 16.5 49.2 36.1 44.7 43.4 48.6 39.7 68.1 44.7 36.8 40.3 45.6 31.1 38.6 49.8 28.0 77.4 51.5 39.2 33.1 47.1 54.7 44.3 11.0 46.5 56.9 52.7 52.9 44.1 49.5 57.5 48.2 50.8 41.8 95.3 77.0 99.5 156.2 36.1 85.7 103.8 58.8 68.5 30.4 79.9 92.4 64.8 132.6 53.3 33.0 61.1 71.4 71.2 70.5 72.0 41.1 34.1 120.6 75.1 35.8 81.0 111.6 76.6 54.3 81.1 119.4 111.4 97.8 61.8 57.6 112.3 60.2 93.7 71.2 87.6 60.8 64.0 124.8 80.8 82.7 116.3 44.5 61.8 116.0 66.1 53.1 195.0 65.6 44.5 16.7 75.0 96.9 43.9 62.2 49.5 72.8 102.8 71.4 107.6 80.8 66.3 111.0 75.7 33.4 11.4 14.3 13.5 18.3 19.0 21.1 42.5 20.6 20.4 16.2 36.1 17.0 12.0 14.3 20.4 28.8 41.9 52.7 39.5 53.2 44.9 41.7 44.7 43.4 40.3 47.1 46.5 48.2 82.4 19.2 26.1 32.3 66.9 71.8 89.5 143.8 51.2 52.6 77.7 61.7 53.6 34.3 81.3 86.5 45.9 79.4 94.3 49.6 281.8 119.5 7.8 56.4 68.9 89.2 84.9 146.9 48.2 122.9 124.2 67.6 42.8 64.7 47.7 70.0 98.6 11.2 95.8 45.4 37.8 80.4 101.7 181.7 103.3 6.3 63.3 124.2 104.9 40.3 270.1 92.9 109.2 34.2 28.3 114.9 51.5 65.1 58.0 149.4 81.1 414.2 50.4 43.7 65.7 48.9 108.8 17.1 25.1 74.7 77.0 139.1 111.4 57.4 80.5 142.9 MFSD14A "DKFZP564L0864, HIAT1" ENSG00000156875 "Major facilitator superfamily domain containing 14A" Q96MC6 1 100038095-100083377 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 131.4" "Group enriched" "Detected in many" 5 "Early spermatids: 303.1;Late spermatids: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA073127, HPA073681" Approved Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA073127: , HPA073681: AB_2686625" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.18e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (2.16e-1)" "unprognostic (7.75e-2)" "unprognostic (2.39e-1)" "unprognostic (1.11e-2)" "unprognostic (1.14e-1)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (3.84e-1)" "unprognostic (1.05e-1)" "unprognostic (5.15e-2)" 29.1 28.5 18.1 26.2 21.1 90.3 27.4 21.2 24.7 25.9 20.8 26.8 19.6 35.3 26.0 29.0 26.6 25.2 19.6 18.2 21.1 29.7 29.5 28.8 28.4 23.3 20.2 30.5 31.5 131.4 18.7 34.1 22.1 33.4 21.8 19.6 23.0 31.4 15.0 24.9 19.6 35.5 21.9 28.4 22.4 35.3 20.0 31.1 27.9 20.1 29.2 33.5 24.0 25.7 54.3 22.2 48.9 25.4 56.0 52.8 41.3 38.9 65.9 51.5 59.9 18.9 37.0 40.5 61.7 50.6 34.1 51.0 44.0 42.8 49.2 35.6 34.8 40.1 32.8 28.6 49.4 65.0 50.2 43.3 64.1 45.5 57.9 45.3 40.2 45.1 49.8 77.2 48.1 16.0 49.3 38.1 56.4 26.2 32.4 34.1 59.6 39.8 54.8 46.9 50.7 45.2 43.8 63.0 66.6 30.9 24.6 65.3 44.5 42.3 29.6 44.9 40.9 72.8 82.4 56.0 46.1 46.6 18.6 80.1 56.0 54.6 49.5 51.4 55.9 46.2 49.6 54.4 55.2 38.8 54.8 51.5 94.8 59.9 45.2 25.6 60.3 72.0 18.1 21.1 21.2 24.7 18.2 21.1 23.3 20.2 22.1 21.9 20.0 25.7 4.5 6.4 11.5 0.0 33.5 0.0 47.5 0.0 43.3 17.8 3.4 1.5 0.0 27.1 3.7 3.7 10.4 37.5 7.8 6.5 1.9 10.1 303.1 1.0 1.7 20.8 13.3 35.8 0.0 7.2 33.5 19.5 18.3 1.5 2.5 0.6 19.6 17.1 23.1 13.5 0.0 9.4 0.0 26.4 0.0 373.8 22.7 15.8 0.0 0.0 22.2 25.1 33.0 0.0 0.0 6.5 17.1 30.5 41.9 56.3 8.1 1.1 5.8 11.6 13.1 25.6 12.8 28.2 22.5 43.4 0.0 58.3 33.7 0.4 9.6 52.3 MIA CD-RAP ENSG00000261857 "MIA SH3 domain containing" Q16674 19 40771648-40777490 "Cancer-related genes, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 57.9;pituitary gland: 76.2;salivary gland: 43.3;stomach 1: 65.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 51.4;Breast myoepithelial cells: 171.7;Melanocytes: 103.2;monocytes: 30.0;Pancreatic endocrine cells: 66.8;Respiratory ciliated cells: 53.9" "Cancer enriched" "Detected in many" 5 "melanoma: 58.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.7" "Group enriched" "Detected in some" 29 "AN3-CA: 90.1;CAPAN-2: 80.6;SK-MEL-30: 271.9;WM-115: 247.7" HPA042369 Approved "Secreted to blood" NA NA 8270000 64000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 4: Stomach - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA042369: AB_10794420" "prognostic favorable (2.08e-4)" "unprognostic (1.30e-1)" "unprognostic (3.15e-1)" "unprognostic (9.02e-3)" "unprognostic (2.27e-1)" "unprognostic (1.11e-1)" "unprognostic (6.37e-3)" "unprognostic (3.67e-2)" "unprognostic (1.61e-1)" "unprognostic (9.37e-2)" "unprognostic (1.17e-1)" "unprognostic (3.19e-1)" "unprognostic (3.29e-8)" "unprognostic (5.88e-2)" "unprognostic (2.44e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" 2.6 2.9 4.9 6.9 5.9 2.9 57.9 5.7 7.5 8.3 5.4 16.9 2.0 1.2 2.0 6.6 3.7 2.9 5.3 4.4 4.8 2.4 2.7 1.9 2.0 5.3 5.0 7.0 1.4 0.0 76.2 2.1 5.6 6.4 4.2 0.4 43.3 3.3 0.7 9.6 5.9 7.6 4.8 7.0 65.8 1.7 5.5 2.4 2.9 1.7 1.6 4.0 5.2 7.9 0.3 0.9 1.5 90.1 1.3 1.2 1.0 0.0 0.0 0.0 0.5 0.5 80.6 0.2 0.0 0.0 0.3 0.2 0.4 4.9 0.1 2.9 0.9 0.0 1.0 0.1 0.4 0.2 0.4 0.7 4.2 0.0 1.5 1.4 0.0 1.4 0.0 0.9 0.0 0.0 0.1 0.0 0.2 5.9 0.3 0.1 0.2 0.0 2.5 0.0 0.2 0.1 0.1 0.0 271.9 3.4 0.5 1.2 0.0 0.2 3.4 0.1 1.0 0.0 0.2 0.9 0.1 0.4 247.7 0.6 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.0 4.9 5.9 5.7 7.5 4.4 4.8 5.3 5.0 5.6 4.8 5.5 7.9 1.0 0.0 0.5 0.0 0.3 5.2 0.1 11.2 0.6 0.0 51.4 171.7 0.6 0.0 4.9 0.0 0.0 0.8 0.5 1.7 0.0 0.5 0.0 0.9 0.0 1.4 0.0 0.0 0.0 3.2 0.1 1.1 14.3 0.2 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.1 4.1 0.0 0.7 0.3 0.6 0.2 103.2 0.0 30.0 0.0 0.0 0.0 0.0 66.8 5.1 0.0 0.1 0.8 0.4 0.0 53.9 0.0 0.0 0.2 1.3 0.1 0.6 6.1 1.3 0.7 0.3 0.8 4.1 0.5 MITF "bHLHe32, MI, WS2, WS2A" ENSG00000187098 "Melanocyte inducing transcription factor" O75030 3 69739464-69968336 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Albinism, Cancer-related genes, Deafness, Disease variant, Microphthalmia, Osteopetrosis, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 133.5;Melanocytes: 585.2;Oligodendrocyte precursor cells: 166.9;Oligodendrocytes: 240.3" "Cancer enriched" "Detected in all" 4 "melanoma: 39.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 5.2;classical monocyte: 9.4;intermediate monocyte: 3.3;myeloid DC: 6.1;non-classical monocyte: 5.9" "Group enriched" "Detected in many" 6 "dendritic cells: 6.1;granulocytes: 5.2;monocytes: 9.4" "Cell line enhanced" "Detected in many" "HMC-1: 89.1;SK-MEL-30: 254.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002578, HPA003259" Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB002578: AB_564111, HPA003259: AB_1079381" "unprognostic (3.29e-1)" "unprognostic (4.26e-2)" "unprognostic (2.98e-2)" "unprognostic (6.04e-2)" "unprognostic (1.03e-1)" "unprognostic (3.25e-1)" "unprognostic (1.04e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-1)" "unprognostic (5.31e-3)" "unprognostic (3.87e-3)" "unprognostic (1.94e-1)" "prognostic favorable (8.35e-10)" "unprognostic (6.37e-2)" "unprognostic (1.08e-1)" "unprognostic (2.04e-1)" "unprognostic (1.73e-1)" 13.8 4.4 5.1 3.8 9.2 1.7 10.0 9.4 6.3 51.3 21.2 18.8 2.8 46.2 4.5 8.9 10.3 16.8 31.1 5.2 9.3 20.0 2.2 9.7 3.4 12.5 9.5 18.7 4.2 16.8 3.8 3.3 10.4 8.4 4.5 1.2 5.1 14.1 50.6 11.0 5.8 46.0 7.0 2.0 9.4 2.3 10.3 2.2 7.6 43.3 1.5 10.6 16.6 13.8 17.2 12.2 1.3 5.1 18.8 0.3 2.0 16.9 9.9 7.8 4.8 6.1 0.8 0.0 4.0 0.3 21.6 8.6 3.7 9.4 8.6 0.0 2.5 37.1 24.5 0.3 4.5 0.8 89.1 15.3 3.9 2.2 8.6 29.1 2.4 0.0 12.3 5.2 5.4 1.2 0.7 1.0 0.7 0.7 8.3 0.1 1.9 7.7 45.2 9.0 0.4 1.9 8.8 3.1 254.1 2.0 0.7 2.3 0.1 3.8 13.3 5.1 3.5 0.6 1.0 0.1 7.7 2.6 9.2 5.2 9.4 0.0 0.0 3.3 0.0 0.0 0.0 0.1 6.1 0.0 0.0 0.0 0.7 1.1 5.9 0.5 0.0 3.1 5.1 9.2 9.4 6.3 5.2 9.3 12.5 9.5 10.4 7.0 10.3 13.8 4.6 28.9 6.8 34.3 0.2 42.8 3.6 16.7 7.4 1.6 1.8 1.8 109.5 11.5 18.2 14.7 0.0 1.3 0.6 0.4 50.9 14.7 1.6 24.5 94.3 7.4 1.2 8.6 14.7 8.8 1.0 38.3 9.7 71.2 106.8 10.9 4.6 2.1 45.8 6.7 133.5 0.3 12.2 30.8 30.9 3.4 44.4 24.3 585.2 50.6 10.6 1.4 0.0 166.9 240.3 7.7 0.0 50.4 0.4 5.2 0.2 24.3 12.5 0.2 13.1 17.8 22.6 4.0 6.3 7.2 18.9 1.1 3.8 5.5 0.6 7.1 MLANA MART1 ENSG00000120215 Melan-A Q16655 9 5890889-5910606 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 42.9" "Cell type enriched" "Detected in some" 23 "Melanocytes: 1718.2" "Cancer enriched" "Detected in single" 556 "melanoma: 277.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 406 "SK-MEL-30: 703.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000057, HPA048662" Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "CAB000057: AB_442107, HPA048662: AB_2680485" "unprognostic (2.52e-2)" "unprognostic (6.87e-2)" "unprognostic (5.20e-2)" "unprognostic (5.61e-2)" "unprognostic (2.58e-2)" "unprognostic (1.46e-1)" "unprognostic (4.53e-1)" "unprognostic (3.32e-1)" "unprognostic (2.82e-2)" "unprognostic (1.71e-3)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (1.45e-2)" "unprognostic (1.60e-1)" "unprognostic (8.01e-2)" "unprognostic (5.78e-2)" "unprognostic (9.43e-2)" 0.1 0.2 0.3 0.4 0.5 0.7 1.4 2.0 0.6 0.1 5.9 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.3 0.4 0.1 0.4 0.5 0.3 0.1 0.1 0.0 0.1 0.1 0.5 0.1 0.0 0.3 1.1 0.0 0.3 42.9 0.1 0.0 0.1 0.2 0.2 0.3 0.6 0.1 0.2 0.0 0.0 0.2 0.3 0.8 0.8 0.6 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.2 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.2 1.7 1.3 1.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.9 0.0 0.3 0.1 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.1 0.4 0.1 703.0 0.1 0.1 0.3 0.6 0.2 0.4 0.1 0.7 0.2 0.7 0.3 0.2 0.4 0.1 0.8 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.1 0.0 0.3 0.1 0.2 0.4 0.2 0.1 0.2 0.1 0.0 0.3 0.5 2.0 0.6 0.2 0.1 0.5 0.3 0.5 0.1 0.6 0.8 0.0 0.0 0.0 0.3 0.0 73.7 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.2 0.9 0.0 0.0 1.3 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 15.5 0.9 0.0 0.2 1718.2 0.0 0.0 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.3 14.5 0.0 0.5 0.1 0.0 0.0 MLIP "C6orf142, CIP, MGC18257" ENSG00000146147 "Muscular LMNA interacting protein" Q5VWP3 6 53929982-54266280 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "heart muscle: 209.2;liver: 131.3;skeletal muscle: 246.6;tongue: 149.5" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 224.9;Excitatory neurons: 244.1" "Group enriched" "Detected in some" 4 "glioma: 0.8;head and neck cancer: 0.5;liver cancer: 1.9;melanoma: 1.4" "Group enriched" "Detected in some" 5 "cerebral cortex: 15.4;hippocampal formation: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HUVEC TERT2: 19.6;SK-MEL-30: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029252, HPA046654" Approved Approved Nucleoplasm NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA029252: AB_2732446, HPA046654: " "unprognostic (7.95e-3)" "unprognostic (4.39e-2)" "unprognostic (2.36e-1)" "unprognostic (1.06e-4)" "unprognostic (2.38e-2)" "unprognostic (1.26e-2)" "unprognostic (5.60e-2)" "unprognostic (2.74e-2)" "unprognostic (1.89e-2)" "unprognostic (1.78e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (1.91e-5)" "unprognostic (7.49e-2)" "unprognostic (2.65e-2)" "unprognostic (5.27e-2)" "unprognostic (3.29e-3)" 3.7 4.3 0.1 0.1 2.2 0.0 3.5 0.0 15.4 1.7 0.0 0.9 0.3 0.2 0.9 12.6 0.7 1.6 209.2 6.0 0.0 0.9 131.3 0.4 0.2 0.0 0.0 0.2 0.8 0.3 0.5 0.1 0.0 1.6 0.7 0.9 6.9 0.3 246.6 17.4 2.6 0.5 0.0 0.1 0.3 1.0 0.0 0.3 6.9 149.5 5.2 1.3 2.5 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 2.4 0.0 0.0 0.0 19.6 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 1.2 0.0 0.1 0.6 1.4 0.0 0.0 0.5 19.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.6 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 15.4 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.9 0.0 0.4 0.1 0.5 0.6 0.1 0.2 0.0 224.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.9 0.0 15.7 0.5 0.5 2.6 0.0 2.7 244.1 0.0 0.0 4.9 0.0 0.4 0.0 0.1 0.7 20.0 0.0 13.5 4.6 3.7 0.0 0.8 0.6 12.9 0.3 0.2 7.2 16.9 0.0 0.0 0.0 5.0 4.2 0.0 0.0 0.0 0.0 0.1 1.0 1.9 0.6 0.1 0.0 17.8 1.9 1.5 0.4 4.1 2.0 0.0 0.1 0.1 0.1 0.1 MLX "bHLHd13, MAD7, MXD7, TCFL4" ENSG00000108788 "MAX dimerization protein MLX" Q9UH92 17 42567072-42573239 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025329, HPA052766, HPA064438" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear membrane, Cytosol" "CAB025329: , HPA052766: AB_2681940, HPA064438: AB_2685265" "unprognostic (2.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-3)" "unprognostic (1.21e-3)" "unprognostic (3.88e-1)" "unprognostic (2.46e-2)" "unprognostic (8.55e-3)" "unprognostic (2.49e-1)" "unprognostic (4.87e-2)" "unprognostic (8.66e-2)" "unprognostic (9.66e-2)" "unprognostic (2.89e-1)" "unprognostic (1.61e-2)" "unprognostic (7.43e-2)" "unprognostic (4.67e-2)" "unprognostic (2.05e-1)" "unprognostic (3.25e-1)" 31.3 28.0 15.8 21.7 16.4 16.4 26.2 16.6 18.0 19.3 19.1 38.5 47.5 15.7 16.6 29.1 17.2 20.3 55.5 16.2 16.9 28.7 51.5 27.9 27.5 16.9 15.9 14.8 32.7 19.6 18.8 21.5 16.8 18.2 38.8 9.3 24.7 18.1 74.4 25.6 42.2 20.3 16.7 24.1 35.4 8.1 16.8 30.1 24.8 86.4 29.4 27.9 20.8 17.2 36.8 41.5 32.1 33.1 48.0 55.3 22.0 53.5 47.5 57.1 51.4 38.0 37.5 43.6 36.8 46.4 51.6 54.4 59.4 34.8 50.0 35.2 55.5 45.4 27.2 43.1 56.3 61.6 63.4 47.9 38.4 45.6 41.8 38.9 42.9 52.2 50.7 38.3 66.2 49.3 87.0 31.3 22.9 90.9 37.3 39.2 66.1 47.5 46.8 44.7 49.9 24.6 23.9 31.2 61.8 42.5 63.3 72.1 30.2 50.7 32.5 55.7 80.8 38.7 47.2 41.2 56.5 39.2 60.8 43.3 64.0 91.4 34.2 80.1 37.6 35.2 35.0 34.6 66.5 30.2 30.5 31.1 82.7 33.7 90.9 35.7 48.0 68.3 15.8 16.4 16.6 18.0 16.2 16.9 16.9 15.9 16.8 16.7 16.8 17.2 31.6 67.3 69.8 9.4 35.6 41.9 28.1 41.5 33.0 29.4 39.8 30.4 24.1 40.0 47.2 27.6 25.0 37.8 35.8 97.7 60.7 48.9 19.1 30.5 29.1 28.2 25.8 42.7 8.0 68.9 49.5 26.0 55.5 26.3 46.7 18.7 27.8 49.7 68.6 25.2 8.1 46.9 30.5 63.4 62.3 24.5 35.1 59.5 32.0 7.5 58.3 13.1 51.5 5.5 7.1 77.5 86.4 31.2 61.8 24.4 132.3 62.1 30.4 31.7 52.6 22.9 31.4 9.3 41.2 45.2 49.9 44.1 38.3 48.0 54.2 36.4 MRPL11 ENSG00000174547 "Mitochondrial ribosomal protein L11" Q9Y3B7 11 66435075-66466738 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057685 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA057685: AB_2683502" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (2.21e-2)" "unprognostic (1.79e-2)" "unprognostic (9.30e-2)" "unprognostic (1.12e-2)" "unprognostic (1.81e-3)" "unprognostic (1.58e-1)" "unprognostic (4.87e-1)" "unprognostic (8.32e-3)" "unprognostic (2.85e-2)" "unprognostic (3.21e-1)" "unprognostic (1.31e-2)" "unprognostic (9.34e-2)" "unprognostic (6.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.72e-1)" 14.6 11.0 12.5 11.8 13.2 23.0 17.3 13.1 21.8 12.8 14.6 21.8 16.5 13.8 16.0 19.4 16.6 8.0 20.6 12.8 12.8 17.1 22.1 10.3 19.0 12.8 12.8 17.7 18.9 17.1 7.9 12.2 13.0 11.6 23.7 11.1 18.0 13.1 49.3 13.3 17.2 14.4 12.6 14.3 17.3 9.8 14.2 18.5 11.6 35.9 20.5 14.7 12.7 12.8 62.1 48.3 44.9 43.3 22.0 24.5 64.2 35.2 40.0 65.8 50.2 135.8 74.7 77.3 59.8 33.6 73.0 52.9 66.5 69.1 46.2 35.8 44.1 48.6 42.6 72.9 26.4 81.4 31.4 29.3 40.6 40.6 49.9 31.7 49.5 73.1 72.1 32.9 28.9 105.6 94.1 129.5 82.3 165.7 69.8 59.2 89.5 97.6 29.1 42.0 47.0 40.8 38.9 58.0 127.4 37.9 66.0 42.4 28.1 39.3 53.1 37.6 42.1 24.1 40.3 87.0 40.7 51.8 27.1 2.1 34.3 7.7 35.9 44.9 38.1 51.6 39.1 35.3 54.5 40.3 40.9 37.8 2.3 37.9 40.7 32.9 43.8 42.5 12.5 13.2 13.1 21.8 12.8 12.8 12.8 12.8 13.0 12.6 14.2 12.8 45.7 12.8 28.3 3.6 61.9 49.8 94.2 80.8 58.1 21.8 69.4 96.3 66.6 60.1 49.0 33.1 8.4 139.6 46.5 66.3 123.3 67.7 40.7 38.0 47.3 51.8 51.0 63.9 4.5 85.6 196.6 54.2 47.4 35.2 31.6 93.9 50.7 82.9 126.2 20.2 4.7 97.3 30.5 60.6 60.3 11.1 50.7 59.5 67.6 1.9 77.6 32.3 66.9 2.5 4.5 59.6 69.4 45.9 61.4 75.0 94.4 124.5 43.7 22.1 26.3 48.9 77.1 78.9 60.5 95.7 49.0 77.4 51.7 68.5 165.2 91.4 MRPL21 ENSG00000197345 "Mitochondrial ribosomal protein L21" Q7Z2W9 11 68891276-68903835 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051657 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA051657: AB_2681565" "unprognostic (1.80e-1)" "unprognostic (6.09e-2)" "unprognostic (4.80e-2)" "unprognostic (8.96e-3)" "unprognostic (9.25e-3)" "prognostic unfavorable (5.97e-4)" "unprognostic (3.23e-2)" "unprognostic (1.51e-1)" "unprognostic (1.09e-1)" "unprognostic (1.06e-1)" "unprognostic (4.84e-2)" "unprognostic (7.36e-2)" "unprognostic (1.26e-2)" "unprognostic (3.73e-2)" "unprognostic (1.72e-1)" "unprognostic (4.36e-2)" "unprognostic (3.12e-1)" 43.5 44.4 56.0 34.0 57.3 60.5 52.5 62.8 71.9 45.3 57.7 67.1 38.7 50.4 48.4 58.4 45.2 27.1 120.2 57.6 59.5 68.0 66.1 31.5 43.8 59.5 57.4 48.6 53.6 56.3 44.7 33.1 59.6 44.1 42.5 29.7 99.5 39.1 131.0 50.4 46.0 35.1 56.9 37.0 53.0 47.0 57.9 37.2 44.7 109.1 42.9 49.8 44.9 56.9 105.2 145.6 86.0 82.3 59.1 63.5 101.4 71.8 77.2 132.8 90.4 297.3 132.7 163.5 157.2 78.0 122.0 129.9 143.8 138.6 102.8 109.7 112.6 114.4 102.4 181.0 116.6 201.4 83.4 95.0 69.4 134.1 156.0 64.7 93.7 115.1 229.2 119.4 80.7 196.7 95.5 210.5 78.0 307.6 210.3 135.2 102.9 253.0 134.0 120.8 139.3 111.3 91.1 181.6 302.7 68.7 188.7 115.4 79.3 90.6 90.6 201.3 135.5 88.9 149.5 232.3 120.6 120.4 125.7 79.6 113.0 61.6 72.4 122.8 77.1 162.2 94.5 78.8 124.2 105.8 89.3 74.1 32.1 93.3 114.2 92.0 113.2 114.0 56.0 57.3 62.8 71.9 57.6 59.5 59.5 57.4 59.6 56.9 57.9 56.9 38.9 35.3 38.7 5.5 47.4 50.2 76.8 145.1 68.9 36.3 56.5 65.4 179.8 67.2 82.0 80.9 8.4 122.8 34.6 127.7 299.3 106.7 176.9 72.2 59.8 50.4 61.7 56.0 5.6 105.3 114.8 53.9 42.8 63.0 65.2 31.8 40.7 115.9 110.4 11.8 6.4 115.6 85.5 56.3 41.3 227.3 74.9 47.0 78.2 1.0 69.8 69.0 34.0 2.0 5.1 86.3 93.0 72.2 63.8 79.6 150.6 272.9 72.8 51.4 26.3 59.3 85.8 86.6 60.5 83.2 51.9 81.3 44.2 55.0 141.6 75.0 MRPL48 CGI-118 ENSG00000175581 "Mitochondrial ribosomal protein L48" Q96GC5 11 73787872-73865133 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 156.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040241, HPA040864" Approved Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA040241: AB_2676899, HPA040864: AB_2677175" "unprognostic (2.41e-1)" "unprognostic (1.80e-2)" "unprognostic (1.56e-2)" "unprognostic (1.18e-3)" "unprognostic (1.99e-1)" "unprognostic (2.90e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (8.89e-2)" "unprognostic (4.41e-2)" "unprognostic (3.97e-2)" "unprognostic (1.14e-1)" "unprognostic (5.85e-2)" "unprognostic (4.61e-3)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-2)" "unprognostic (3.30e-1)" 10.8 17.4 30.3 10.2 33.8 12.1 13.3 33.6 50.0 16.8 31.1 17.5 14.1 12.3 14.8 16.6 13.6 5.6 22.5 30.0 31.9 24.2 21.2 10.2 12.8 35.5 32.3 14.2 19.3 21.2 10.9 10.6 36.5 14.6 15.8 11.5 13.9 10.0 28.6 12.5 14.8 8.1 31.6 14.5 15.1 5.8 31.9 23.2 14.1 26.9 14.4 12.3 14.6 41.5 29.6 33.2 36.7 20.8 20.9 16.8 16.2 18.0 20.3 27.9 23.0 63.9 26.6 71.0 35.7 25.6 18.7 35.6 37.3 37.7 24.6 28.3 40.9 36.3 33.3 45.4 24.5 61.5 24.9 14.1 41.0 23.8 33.0 24.5 39.1 40.5 46.9 37.7 28.1 47.1 72.9 58.9 27.5 95.5 35.0 32.1 43.8 81.3 31.0 35.3 28.9 28.0 14.2 48.8 156.9 17.0 31.4 38.5 13.6 21.6 27.9 15.3 24.2 18.1 39.3 103.1 9.5 39.8 18.0 40.7 23.6 12.5 25.8 30.4 27.3 27.5 30.1 31.6 33.6 29.8 32.3 31.3 4.1 28.1 28.1 37.6 35.3 29.5 30.3 33.8 33.6 50.0 30.0 31.9 35.5 32.3 36.5 31.6 31.9 41.5 17.3 9.6 20.5 11.1 29.4 19.2 35.3 66.7 25.6 10.2 28.5 35.1 33.0 21.5 33.9 25.8 4.2 92.0 27.6 28.3 88.0 37.1 6.3 31.0 21.0 18.9 24.1 36.6 16.1 39.7 73.5 22.5 19.9 22.9 21.0 32.5 16.4 28.0 42.9 15.2 22.6 38.0 42.7 25.4 19.4 16.5 18.3 20.5 44.4 3.7 29.4 16.6 22.6 24.6 45.2 30.9 36.1 18.0 30.0 22.0 63.4 76.5 39.1 8.5 0.0 22.5 29.7 18.6 26.3 38.2 19.7 59.8 26.8 26.6 49.1 37.1 MVB12A "FAM125A, FLJ32495" ENSG00000141971 "Multivesicular body subunit 12A" Q96EY5 19 17405722-17433724 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041885, HPA042231" Approved Supported Vesicles NA No "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041885: AB_10964218, HPA042231: AB_10961043" "unprognostic (1.34e-2)" "prognostic favorable (3.26e-4)" "unprognostic (1.48e-1)" "unprognostic (2.35e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" "unprognostic (5.96e-3)" "unprognostic (8.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.77e-1)" "unprognostic (9.93e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-1)" "unprognostic (2.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.33e-2)" 21.3 28.4 10.5 17.3 11.5 18.2 21.4 11.4 12.3 18.6 11.8 16.7 29.1 17.3 7.4 29.5 22.0 18.7 13.1 10.0 10.3 20.2 19.9 15.5 21.7 14.0 11.0 34.0 20.0 22.2 7.4 19.2 11.6 13.7 11.6 1.2 24.2 17.5 14.4 24.7 22.0 11.6 12.3 22.3 20.9 5.2 11.4 24.0 21.2 12.4 19.3 17.0 18.0 13.5 51.2 23.4 12.1 33.9 15.7 28.8 71.1 18.3 28.4 33.8 40.8 20.1 60.5 32.7 52.7 28.2 28.8 25.5 19.5 35.5 9.0 37.6 60.7 9.5 41.8 44.0 50.3 13.0 29.1 28.2 28.5 29.1 18.0 25.5 40.7 29.9 26.8 65.2 15.6 32.2 24.6 26.2 17.0 40.8 63.9 34.7 14.8 53.1 32.4 21.2 25.3 40.7 19.6 30.2 77.6 10.9 40.1 30.9 21.7 31.5 18.4 35.1 20.5 59.3 72.9 35.0 34.1 49.3 38.9 57.4 61.7 42.9 33.0 66.9 31.0 23.3 34.0 32.0 60.5 29.8 28.0 27.5 36.0 38.2 53.4 53.3 57.2 36.2 10.5 11.5 11.4 12.3 10.0 10.3 14.0 11.0 11.6 12.3 11.4 13.5 67.5 9.6 8.2 5.9 16.4 39.0 41.4 65.1 42.1 5.3 53.6 61.8 5.6 48.6 33.5 46.0 6.2 60.7 18.1 85.0 54.8 78.7 13.5 30.1 26.8 47.7 26.5 8.4 2.2 48.4 99.0 38.6 43.3 30.2 21.6 45.7 62.4 28.0 72.3 3.3 3.2 48.5 50.8 44.9 30.8 16.3 43.5 31.2 32.0 11.2 46.7 32.7 19.6 4.0 7.3 63.4 84.1 47.0 23.5 19.0 104.4 61.3 36.4 13.8 6.6 22.8 40.9 11.8 12.3 58.3 43.9 40.6 21.2 44.3 57.1 45.0 MXI1 "bHLHc11, MAD2, MXD2, MXI" ENSG00000119950 "MAX interactor 1, dimerization protein" P50539 10 110207605-110287365 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 264.7;Oligodendrocytes: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 108.2;SK-MEL-30: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035319, HPA035320, HPA056762" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Nucleoli rim, Cytosol" "HPA035319: AB_10670588, HPA035320: , HPA056762: AB_2683229" "unprognostic (1.77e-2)" "unprognostic (2.02e-1)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.71e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (1.59e-1)" "unprognostic (9.26e-3)" "prognostic unfavorable (9.17e-4)" "prognostic unfavorable (1.02e-5)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (2.29e-1)" "unprognostic (2.96e-1)" 34.0 32.7 86.8 13.2 98.0 68.0 45.1 92.9 106.1 38.8 67.0 55.9 24.4 45.6 36.2 52.3 42.4 32.8 63.2 84.9 91.1 39.2 51.1 26.4 13.8 93.9 91.8 81.4 44.7 50.6 22.1 28.5 94.7 41.0 35.0 80.2 80.1 52.1 47.3 47.6 29.6 29.8 89.3 14.8 28.0 23.3 94.9 31.2 54.5 53.2 12.3 34.6 41.2 110.8 18.2 8.3 18.0 39.6 30.7 21.4 7.4 11.1 39.2 7.1 23.1 3.2 33.5 24.6 17.6 20.0 11.3 24.3 23.5 27.8 20.0 13.5 30.9 7.3 15.7 14.5 19.5 14.3 14.4 21.7 96.0 12.4 55.2 108.2 7.1 17.5 26.9 54.9 11.3 12.3 10.1 26.1 7.7 31.0 21.2 6.1 26.0 39.9 22.8 1.6 34.3 52.4 11.1 7.3 167.1 23.3 9.9 42.2 7.7 13.5 21.0 13.6 5.6 44.6 26.1 10.0 34.3 46.1 12.7 1.8 2.7 9.7 2.7 2.3 5.1 3.9 5.1 2.8 1.6 3.6 7.7 1.9 5.6 1.4 5.0 1.7 4.8 2.0 86.8 98.0 92.9 106.1 84.9 91.1 93.9 91.8 94.7 89.3 94.9 110.8 28.9 16.0 16.8 139.1 27.9 58.0 57.9 22.8 51.2 49.9 67.2 66.8 80.2 41.5 27.6 33.1 47.9 5.4 23.0 160.7 46.9 19.3 5.1 29.1 36.4 34.1 16.9 264.7 60.8 14.8 20.1 36.0 15.8 37.3 3.8 19.1 27.8 56.6 11.1 52.2 102.5 20.1 18.3 24.1 20.5 8.8 45.1 22.6 104.9 30.9 29.9 144.2 9.2 131.7 214.9 10.4 52.5 55.7 22.5 73.4 57.0 67.1 25.3 46.0 46.0 69.6 63.0 23.8 28.2 37.4 67.3 9.7 36.9 27.4 16.6 36.9 MYEF2 "FLJ11213, HsT18564, KIAA1341, MEF-2" ENSG00000104177 "Myelin expression factor 2" 15 48134632-48178353 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 87.8;Oligodendrocyte precursor cells: 88.4;Spermatocytes: 106.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 101.9;SCLC-21H: 90.8;SK-MEL-30: 91.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004883 Supported Supported Nucleoplasm NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA004883: AB_1079436" "unprognostic (4.30e-2)" "unprognostic (8.59e-2)" "unprognostic (5.01e-2)" "unprognostic (2.17e-1)" "unprognostic (2.02e-2)" "unprognostic (7.18e-3)" "unprognostic (2.76e-3)" "unprognostic (6.81e-2)" "unprognostic (2.35e-1)" "unprognostic (4.09e-2)" "unprognostic (1.55e-5)" "unprognostic (1.32e-2)" "unprognostic (3.76e-3)" "unprognostic (7.94e-2)" "unprognostic (2.51e-2)" "unprognostic (7.26e-2)" "unprognostic (4.05e-1)" 4.7 15.0 17.2 4.9 18.1 1.6 7.7 26.0 23.5 2.3 13.5 11.4 3.6 5.7 10.0 2.5 12.1 6.9 8.8 17.4 21.1 17.8 0.5 5.8 7.0 17.6 17.1 1.7 14.2 13.9 22.8 1.4 16.9 8.9 4.9 33.1 6.4 10.5 1.4 4.4 4.9 7.5 17.2 6.2 9.2 28.2 17.4 10.4 5.5 2.2 7.6 3.7 1.3 20.8 0.3 30.1 101.9 63.9 1.0 0.1 0.0 31.4 8.3 15.7 6.9 12.1 12.8 22.1 40.2 7.1 10.9 0.2 43.1 1.9 20.9 60.3 16.5 13.5 0.0 5.1 5.1 15.6 10.5 0.5 1.2 0.2 2.1 47.5 28.5 30.5 2.2 30.5 12.8 17.6 24.0 0.2 44.1 7.5 5.3 0.0 8.0 0.7 51.2 5.8 90.8 69.7 0.0 9.2 91.9 47.6 49.3 19.7 18.6 5.0 24.3 18.9 73.6 13.5 54.4 0.1 9.3 0.1 20.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.2 0.1 0.0 0.4 0.0 0.2 0.2 0.0 17.2 18.1 26.0 23.5 17.4 21.1 17.6 17.1 16.9 17.2 17.4 20.8 15.9 12.8 16.8 56.8 13.9 0.8 2.3 1.2 1.2 80.4 26.2 17.0 9.4 7.2 11.6 49.7 79.2 0.6 7.9 3.3 31.3 20.5 70.7 40.1 3.0 10.9 52.1 8.8 80.8 11.3 0.2 5.5 4.1 18.3 4.5 47.6 6.8 0.1 0.4 82.4 87.8 8.2 2.0 1.0 6.8 41.0 2.1 3.9 10.6 22.5 3.8 33.5 3.1 88.4 43.9 11.0 6.8 1.2 5.8 7.3 0.5 26.7 47.7 61.0 0.0 7.1 13.2 106.1 25.3 0.5 1.0 0.0 7.8 2.8 6.9 1.6 MYOZ2 "C4orf5, CS-1, FATZ-2" ENSG00000172399 "Myozenin 2" Q9NPC6 4 119135832-119187789 "Disease related genes, Predicted intracellular proteins" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 771.4;skeletal muscle: 225.5;tongue: 173.4" "Cell type enriched" "Detected in some" 51 "Cardiomyocytes: 2275.3" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.0;HSkMC: 2.3;SK-MEL-30: 6.2;U-87 MG: 6.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA035763, HPA035764" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "HPA035763: AB_2674770, HPA035764: AB_10696509" "unprognostic (2.53e-1)" "unprognostic (9.20e-2)" "unprognostic (6.94e-2)" "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (2.34e-2)" "unprognostic (5.71e-1)" "unprognostic (2.18e-1)" "unprognostic (4.77e-2)" "unprognostic (4.04e-1)" "unprognostic (8.25e-2)" "unprognostic (5.07e-2)" "unprognostic (6.19e-7)" "unprognostic (6.66e-4)" "unprognostic (2.43e-1)" "unprognostic (3.06e-1)" "unprognostic (2.83e-2)" 0.6 0.3 0.2 0.0 0.3 0.0 2.1 0.1 0.5 0.7 0.0 1.0 0.0 2.0 0.3 1.0 1.0 0.3 771.4 0.2 0.3 0.7 0.1 0.9 0.3 0.2 0.2 0.6 0.1 0.0 0.2 0.2 0.1 4.8 0.1 0.0 1.8 0.3 225.5 0.5 0.4 0.8 0.2 0.6 0.6 1.0 0.3 0.3 0.3 173.4 0.1 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 2.3 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.2 1.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.5 0.2 0.3 0.2 0.2 0.1 0.2 0.3 0.2 0.1 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 2275.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.4 20.8 0.0 0.0 3.4 2.2 0.0 44.1 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.3 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.7 0.0 0.2 0.0 2.9 0.0 0.0 6.6 6.9 22.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NAB2 MADER ENSG00000166886 "NGFI-A binding protein 2" Q15742 12 57089043-57095476 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 56.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 98.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004510, HPA027464" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "CAB004510: AB_627982, HPA027464: AB_10601138" "prognostic favorable (7.41e-4)" "unprognostic (4.04e-2)" "unprognostic (2.20e-3)" "unprognostic (2.43e-2)" "unprognostic (4.74e-2)" "unprognostic (2.10e-1)" "unprognostic (1.88e-3)" "unprognostic (1.80e-1)" "unprognostic (5.85e-2)" "unprognostic (1.19e-1)" "unprognostic (2.13e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.38e-6)" "unprognostic (1.95e-1)" "unprognostic (9.76e-2)" "unprognostic (5.67e-3)" "unprognostic (6.19e-3)" 21.8 16.1 25.2 9.9 26.8 6.8 14.2 30.3 31.0 33.7 24.0 29.8 10.1 32.3 21.0 24.5 31.0 17.4 20.5 28.3 25.0 20.1 22.3 24.0 12.0 23.2 23.1 51.1 10.2 19.5 35.4 11.1 22.1 25.4 5.0 10.7 11.6 16.6 7.6 33.4 15.7 13.4 21.6 16.9 15.9 16.8 25.4 17.4 20.7 9.9 10.4 27.7 33.8 24.8 15.2 9.8 49.2 45.2 43.3 56.7 5.5 44.1 40.8 28.0 23.1 15.6 8.7 9.6 17.6 44.4 8.1 27.0 16.9 34.0 14.3 4.0 4.5 11.4 8.1 16.6 33.2 9.1 26.5 64.4 36.1 32.6 10.9 43.7 7.5 7.2 26.5 9.6 32.4 73.4 14.0 44.5 9.9 12.9 16.6 10.4 64.1 5.1 11.8 6.0 5.5 13.1 21.9 12.5 98.3 12.3 28.0 20.0 8.4 40.7 34.1 28.8 13.2 22.7 6.0 5.1 39.5 5.9 25.1 0.0 1.1 0.2 0.5 2.7 0.6 0.9 0.9 0.7 0.6 2.3 1.1 1.1 0.4 0.4 2.9 0.0 1.0 0.6 25.2 26.8 30.3 31.0 28.3 25.0 23.2 23.1 22.1 21.6 25.4 24.8 7.6 12.8 13.0 5.9 11.6 29.6 19.5 23.4 39.3 20.3 17.3 13.8 2.9 2.8 13.6 9.2 2.1 3.7 4.9 1.1 7.9 7.4 0.6 22.9 21.2 13.7 6.6 4.8 11.4 1.4 10.5 19.7 8.6 25.4 17.1 7.8 18.2 17.1 11.2 10.1 5.4 1.1 10.2 16.3 43.7 2.9 19.6 14.3 21.4 8.4 1.6 7.9 1.0 1.0 1.9 4.1 0.0 18.8 8.7 12.9 8.7 5.6 5.9 4.4 19.7 9.8 16.3 2.6 18.7 23.4 32.5 56.2 10.7 2.5 1.5 8.6 NAT8L "FLJ37478, Hcml3, Shati" ENSG00000185818 "N-acetyltransferase 8 like" Q8N9F0 4 2059327-2069089 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adipose tissue: 43.5;brain: 99.0" "Cell type enhanced" "Detected in some" "Astrocytes: 126.7;Excitatory neurons: 46.0;Horizontal cells: 80.8;Inhibitory neurons: 37.6;Muller glia cells: 25.0" "Group enriched" "Detected in many" 6 "endometrial cancer: 6.2;glioma: 17.2;melanoma: 14.6;ovarian cancer: 8.0;thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 20.8;SCLC-21H: 25.8;SK-MEL-30: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040677 Approved Mitochondria NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA040677: AB_2732486" "unprognostic (1.32e-2)" "unprognostic (8.62e-2)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.01e-5)" "unprognostic (2.56e-1)" "unprognostic (2.63e-4)" "unprognostic (6.58e-2)" "unprognostic (1.79e-1)" "unprognostic (2.90e-2)" "unprognostic (4.54e-1)" "unprognostic (3.70e-2)" "unprognostic (7.06e-2)" "unprognostic (1.78e-3)" "unprognostic (7.24e-3)" "unprognostic (1.14e-2)" "unprognostic (2.10e-2)" "unprognostic (1.35e-2)" 43.5 0.7 56.1 0.1 46.4 0.0 1.6 42.9 99.0 0.0 0.6 0.2 0.1 0.3 1.3 0.1 0.9 0.1 0.8 45.8 29.0 5.3 0.0 0.0 0.2 52.3 46.4 0.2 2.3 0.9 1.8 0.1 57.5 1.0 0.1 3.7 2.3 1.6 5.7 1.0 0.2 0.2 33.0 0.3 0.4 9.0 88.8 0.2 0.3 2.5 0.0 0.0 0.0 38.9 0.1 9.2 4.9 10.0 0.9 0.0 5.7 0.2 0.0 0.2 0.0 4.1 0.3 0.0 1.9 0.0 1.5 0.1 11.1 0.0 0.1 0.0 13.2 0.1 2.1 6.6 1.5 14.5 6.9 0.0 0.2 0.0 0.0 1.8 0.0 3.4 11.5 0.0 0.4 6.2 0.2 20.8 14.1 0.0 4.1 0.7 2.3 0.4 0.2 0.5 25.8 8.6 6.6 0.0 21.4 0.8 0.7 8.3 0.0 0.0 3.3 0.1 5.6 0.0 0.0 0.2 0.0 6.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 56.1 46.4 42.9 99.0 45.8 29.0 52.3 46.4 57.5 33.0 88.8 38.9 0.5 0.0 0.0 126.7 0.0 0.3 0.0 0.0 0.0 14.5 1.4 2.2 2.6 0.0 0.0 1.8 6.2 0.0 5.4 0.0 0.0 4.6 1.1 1.7 0.1 0.4 1.8 0.0 46.0 0.6 0.1 0.2 0.0 1.0 0.0 21.9 0.0 0.0 0.8 80.8 37.6 0.0 0.0 0.0 0.3 3.8 0.0 0.7 10.6 17.8 0.0 25.0 0.0 23.1 15.7 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.8 0.5 1.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 NBL1 "D1S1733E, DAN, DAND1, NB, NO3" ENSG00000158747 "NBL1, DAN family BMP antagonist" P41271 1 19596979-19658456 "Predicted intracellular proteins, Predicted secreted proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 676.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.1;Leydig cells: 386.8;Paneth cells: 313.2;Peritubular cells: 356.9;Prostatic glandular cells: 293.3;Proximal enterocytes: 413.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 431.7;HSkMC: 305.6;SK-MEL-30: 473.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007394, CAB026132" Uncertain "Secreted in other tissues" NA NA 8100000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026132: , HPA007394: AB_10601272" "unprognostic (1.65e-1)" "unprognostic (1.65e-2)" "unprognostic (9.03e-2)" "unprognostic (2.85e-1)" "unprognostic (1.33e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (3.92e-1)" "unprognostic (7.88e-2)" "unprognostic (3.10e-2)" "unprognostic (1.92e-2)" "unprognostic (1.39e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.21e-2)" "unprognostic (2.26e-2)" 166.3 27.7 116.1 61.4 115.2 5.7 183.3 90.6 156.0 676.6 125.7 259.3 195.0 253.9 48.3 206.8 281.5 202.6 119.1 147.1 117.1 67.2 5.8 312.0 57.3 101.7 140.7 635.9 27.1 48.3 125.3 21.6 117.0 376.0 109.3 14.5 65.4 113.5 26.6 199.1 314.1 113.0 95.0 25.8 139.9 44.5 109.5 25.3 85.9 28.4 22.4 246.5 373.8 97.3 138.8 42.9 7.2 38.5 431.7 222.7 19.7 195.5 238.6 64.1 64.7 11.8 242.6 0.2 122.2 245.7 44.8 153.4 40.8 180.1 19.6 132.9 23.0 6.8 40.5 72.4 69.4 0.5 3.1 305.6 162.0 94.6 57.6 19.1 48.7 8.0 1.4 0.4 20.6 20.4 0.4 11.7 2.9 142.3 65.2 6.4 0.1 4.7 122.5 16.6 3.1 102.2 31.2 1.2 473.8 7.1 160.2 24.3 68.9 62.4 49.7 180.0 30.3 0.9 1.1 0.8 45.4 0.6 19.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.4 0.0 0.0 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.1 116.1 115.2 90.6 156.0 147.1 117.1 101.7 140.7 117.0 95.0 109.5 97.3 150.4 3.2 2.3 0.0 2.9 174.6 237.3 22.6 107.0 35.5 41.5 32.8 43.5 55.8 11.9 36.8 6.2 1.0 5.1 395.1 3.9 43.0 2.0 15.6 55.7 84.3 54.5 3.4 0.0 7.7 2.6 241.4 39.8 10.1 13.4 80.9 47.8 1.5 54.6 6.7 0.0 244.6 12.2 2.2 76.6 13.1 386.8 6.6 60.5 0.0 5.8 13.4 0.0 0.0 0.0 97.5 313.2 356.9 1.1 293.3 413.8 19.7 24.5 10.2 131.5 14.0 142.9 1.4 7.6 61.4 202.4 1.4 29.6 15.1 220.4 206.5 NCK2 NCKbeta ENSG00000071051 "NCK adaptor protein 2" O43639 2 105744912-105894274 "Plasma proteins, Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 184.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016116, HPA031004" Approved NA NA 87000 "Cluster 35: T-regs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 24: Non-specific - Transcription regulation" "CAB016116: AB_2150588, HPA031004: AB_10795571" "unprognostic (2.39e-1)" "unprognostic (3.48e-1)" "unprognostic (6.67e-2)" "unprognostic (4.43e-2)" "unprognostic (1.66e-1)" "unprognostic (1.53e-1)" "unprognostic (5.85e-3)" "unprognostic (4.04e-2)" "unprognostic (4.88e-2)" "unprognostic (1.22e-1)" "unprognostic (9.62e-2)" "unprognostic (2.31e-1)" "unprognostic (1.50e-1)" "unprognostic (8.24e-2)" "unprognostic (2.14e-2)" "unprognostic (7.21e-3)" "unprognostic (4.22e-2)" 37.8 19.7 18.6 20.5 19.2 17.6 33.6 26.3 29.0 36.4 16.7 39.1 54.7 29.7 18.9 68.8 25.4 19.0 31.9 27.9 18.4 28.9 11.1 37.1 27.6 21.8 22.4 25.1 39.8 13.6 19.7 36.8 22.0 24.7 16.4 10.3 46.8 18.7 53.5 33.4 51.7 17.9 22.5 52.0 40.3 27.3 23.9 18.6 28.3 27.2 19.1 35.6 50.4 20.4 25.8 20.2 51.6 23.9 15.0 10.7 73.3 19.0 25.0 21.6 12.5 58.8 20.9 11.2 23.4 24.2 31.0 25.1 21.9 47.7 14.6 79.5 24.5 5.0 9.4 37.8 39.2 28.1 9.8 21.4 34.0 23.5 30.0 18.7 22.0 27.3 7.7 38.5 17.9 21.7 29.3 48.2 28.8 21.6 23.0 23.4 36.2 41.7 28.1 51.2 32.9 45.4 14.4 37.2 184.4 30.4 13.6 70.3 25.0 37.9 55.2 1.0 27.2 28.8 19.6 3.8 16.7 24.5 61.6 26.2 1.0 12.5 7.0 1.0 9.2 7.7 13.1 11.8 1.2 11.1 13.6 12.5 9.3 11.9 1.0 1.8 24.5 5.0 18.6 19.2 26.3 29.0 27.9 18.4 21.8 22.4 22.0 22.5 23.9 20.4 41.8 16.0 7.9 28.1 32.8 17.6 13.9 14.2 7.4 13.5 27.1 35.9 21.3 71.4 9.6 16.5 12.5 39.0 30.3 31.2 7.9 28.1 15.5 18.0 21.8 23.7 19.2 2.5 60.0 18.8 15.2 16.2 13.3 19.9 5.7 33.0 18.2 2.3 26.0 82.4 48.4 23.1 18.3 14.2 13.9 9.2 23.6 18.7 10.6 77.8 10.5 61.4 18.6 24.6 18.3 29.9 29.2 28.2 15.8 17.7 51.3 8.4 18.9 4.6 32.9 33.1 54.4 4.2 9.6 10.7 16.8 29.7 52.4 18.1 31.2 30.0 NCKAP5L KIAA1602 ENSG00000167566 "NCK associated protein 5 like" Q9HCH0 12 49791146-49828750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Leydig cells: 68.3;Peritubular cells: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041034 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "HPA041034: AB_10796235" "unprognostic (3.35e-2)" "unprognostic (1.68e-3)" "unprognostic (2.87e-3)" "unprognostic (1.06e-1)" "unprognostic (4.79e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (2.07e-4)" "unprognostic (2.51e-2)" "unprognostic (8.65e-2)" "unprognostic (1.85e-2)" "prognostic favorable (4.87e-4)" "unprognostic (2.94e-1)" "prognostic unfavorable (1.16e-5)" "unprognostic (3.29e-2)" "unprognostic (3.80e-1)" "unprognostic (5.94e-2)" "unprognostic (1.15e-1)" 13.3 27.6 9.9 6.4 12.1 3.1 11.2 9.8 14.1 14.7 8.6 12.3 2.9 12.4 1.4 6.3 11.9 5.4 22.2 10.0 9.9 12.8 10.9 16.2 4.4 13.7 11.4 14.6 7.9 5.0 14.0 9.0 11.7 15.0 1.0 2.6 8.3 4.6 10.0 6.6 6.7 4.7 9.1 13.1 8.7 15.7 12.8 5.8 14.0 4.6 1.9 11.6 10.3 15.7 5.3 8.9 15.5 15.4 9.7 7.2 20.6 8.9 9.6 12.8 10.6 12.4 1.6 3.2 15.0 9.1 4.9 1.8 6.4 9.4 3.4 3.3 9.0 11.7 11.3 12.1 24.4 4.6 24.4 17.0 10.8 13.8 6.4 16.1 15.1 11.7 11.4 0.1 8.3 12.9 12.0 16.5 18.7 1.7 9.9 14.5 16.0 0.9 9.9 7.3 5.4 24.3 13.6 14.6 25.4 8.4 25.6 9.4 11.9 11.9 12.5 6.1 4.3 0.3 0.0 4.1 9.6 5.3 3.6 0.0 0.6 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.5 0.1 0.1 0.1 0.2 0.2 0.4 0.5 0.0 0.3 9.9 12.1 9.8 14.1 10.0 9.9 13.7 11.4 11.7 9.1 12.8 15.7 18.0 6.4 1.1 16.6 7.6 12.7 8.2 8.4 22.8 44.6 19.2 15.6 2.7 5.7 6.2 11.0 112.6 10.6 19.2 1.2 0.0 5.3 1.2 15.6 16.9 11.6 9.0 1.7 10.0 3.8 12.9 17.4 3.1 8.6 0.0 29.5 10.8 4.6 15.9 30.3 13.2 1.3 8.2 12.9 24.8 4.8 68.3 20.7 5.4 13.1 12.4 7.0 7.2 13.0 21.8 3.2 0.4 82.8 2.2 5.7 0.2 2.4 6.6 25.2 0.0 49.3 15.5 3.0 4.8 8.2 7.2 2.5 10.0 43.2 1.6 3.5 NDUFB4 B15 ENSG00000065518 "NADH:ubiquinone oxidoreductase subunit B4" O95168 3 120596328-120602507 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 945.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1493.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051739, HPA064441" Enhanced Supported "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Nuclear membrane" "HPA051739: AB_2681585, HPA064441: " "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (6.95e-2)" "unprognostic (4.69e-2)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (1.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.35e-3)" "unprognostic (9.66e-3)" "unprognostic (7.97e-2)" "unprognostic (2.84e-1)" "unprognostic (3.69e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "prognostic favorable (1.79e-4)" 148.6 338.4 159.7 90.3 169.1 112.4 145.1 175.9 203.2 126.2 173.2 170.0 147.8 117.9 133.8 159.5 113.0 85.7 619.5 163.5 178.4 232.4 187.4 102.9 93.8 168.3 163.0 119.8 137.4 260.3 170.2 76.8 168.6 118.1 148.7 100.2 148.4 117.4 945.3 144.5 135.6 103.4 170.7 112.1 162.3 106.5 161.7 125.6 113.1 562.2 114.2 133.5 142.1 172.8 294.8 204.3 246.7 248.5 151.0 181.4 199.2 157.0 212.1 205.4 224.5 200.9 219.8 147.8 311.6 177.8 255.6 272.5 191.3 202.7 155.7 227.5 212.6 226.1 205.7 208.1 90.4 202.7 256.8 161.3 268.5 98.9 125.8 246.0 258.5 271.7 138.5 219.2 220.9 224.1 398.6 294.8 193.9 478.9 554.7 228.8 141.0 325.8 337.3 177.9 273.8 283.4 186.5 205.7 360.0 162.0 348.0 319.9 199.8 179.0 233.2 76.9 226.5 263.2 260.1 454.3 283.6 279.8 250.8 205.0 164.8 197.2 156.0 229.5 162.2 231.6 215.2 176.8 213.9 176.3 182.2 181.8 101.6 152.7 238.2 267.9 300.6 205.7 159.7 169.1 175.9 203.2 163.5 178.4 168.3 163.0 168.6 170.7 161.7 172.8 274.1 163.5 162.6 36.9 167.0 222.3 289.0 612.6 190.6 137.8 290.1 351.3 1493.1 311.7 348.3 320.0 58.4 366.0 158.1 472.4 1226.7 556.7 999.2 259.9 188.9 235.7 298.7 196.9 22.6 620.9 421.0 213.7 175.3 293.5 174.8 139.4 183.5 513.9 330.3 84.1 22.0 526.3 451.6 240.2 247.9 164.6 275.2 196.2 434.0 15.9 339.2 340.7 186.4 13.0 31.2 567.9 581.8 277.2 283.2 243.2 613.4 1225.1 266.2 168.4 256.4 208.1 259.0 418.9 87.5 288.4 251.5 352.4 168.1 271.3 462.8 344.0 NDUFS8 "CI-23k, TYKY" ENSG00000110717 "NADH:ubiquinone oxidoreductase core subunit S8" O00217 11 68030617-68036644 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 833.5;Late spermatids: 797.2;Proximal tubular cells: 927.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018524, HPA067429" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA018524: AB_1854355, HPA067429: " "unprognostic (2.90e-1)" "unprognostic (1.41e-3)" "unprognostic (2.41e-1)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-1)" "unprognostic (7.75e-2)" "unprognostic (3.15e-1)" "unprognostic (1.77e-2)" "unprognostic (3.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (3.27e-8)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (9.45e-2)" 99.2 308.4 141.2 38.8 153.2 56.2 87.7 157.2 180.4 73.2 172.3 142.0 81.4 89.2 27.2 115.3 81.3 29.1 468.2 144.2 152.0 188.6 152.0 73.1 42.2 149.6 144.9 68.2 97.7 74.6 130.6 33.6 145.8 118.2 36.7 49.5 96.2 66.7 406.4 93.0 84.4 39.0 142.2 76.9 137.8 104.7 154.0 40.3 101.8 275.5 30.1 94.4 76.0 150.2 152.9 366.4 94.6 137.0 70.9 63.5 132.4 102.3 88.5 155.6 118.9 338.4 159.6 118.4 186.8 85.9 134.6 181.2 108.8 128.4 53.1 139.4 264.9 107.2 217.1 186.3 171.8 99.1 112.1 80.5 126.5 111.1 124.8 82.0 106.2 159.9 110.3 121.1 99.2 358.6 219.2 216.9 125.2 377.7 308.0 154.4 95.9 384.9 192.8 123.3 125.5 102.2 75.7 171.7 392.3 66.5 245.6 105.9 84.1 155.6 133.9 224.8 148.8 165.2 188.5 99.7 252.3 121.8 111.2 84.7 220.1 124.0 182.4 232.0 170.1 183.3 154.6 165.5 309.4 156.3 146.2 164.2 20.7 309.6 131.7 324.3 202.2 232.4 141.2 153.2 157.2 180.4 144.2 152.0 149.6 144.9 145.8 142.2 154.0 150.2 88.7 89.8 90.1 18.6 92.3 85.4 95.5 284.3 104.7 83.4 147.2 156.7 301.9 143.0 164.9 213.3 54.2 279.6 97.8 301.0 833.5 200.8 225.7 101.1 74.8 85.3 205.0 149.8 13.6 199.3 165.9 109.6 147.3 79.7 95.8 156.5 73.5 231.7 276.6 50.5 19.3 277.2 240.1 124.1 108.0 797.2 100.6 128.7 163.7 13.1 187.4 143.6 128.8 12.1 15.4 173.7 194.9 108.0 157.8 118.6 337.1 927.8 120.8 118.7 59.2 81.2 208.6 105.9 72.7 209.7 116.2 172.4 102.7 278.7 318.2 139.1 NDUFV1 CI-51K ENSG00000167792 "NADH:ubiquinone oxidoreductase core subunit V1" P49821 11 67605653-67612554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 526.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 482.4;Proximal tubular cells: 499.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045211, HPA075051" Enhanced Supported Mitochondria,Cytosol No No 37000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA045211: AB_10962830, HPA075051: AB_2686732" "unprognostic (4.57e-2)" "unprognostic (2.17e-2)" "unprognostic (2.84e-1)" "unprognostic (7.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.54e-3)" "unprognostic (1.19e-1)" "unprognostic (3.31e-2)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "unprognostic (4.02e-2)" "unprognostic (3.03e-2)" "prognostic favorable (7.49e-10)" "unprognostic (1.12e-2)" "unprognostic (1.80e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" 95.0 126.5 87.6 52.5 93.7 72.5 90.9 105.6 107.1 93.9 104.8 142.3 124.5 85.2 33.8 114.0 84.6 47.1 400.2 91.6 97.0 188.4 187.0 77.1 66.7 103.3 91.5 101.9 117.2 169.8 84.5 46.7 110.4 77.4 73.7 81.6 90.2 73.2 526.2 117.7 96.6 51.1 86.9 98.8 132.0 76.0 104.9 51.6 107.6 440.5 62.8 88.1 88.6 99.9 132.9 133.6 68.8 141.3 85.6 83.4 130.6 84.1 76.4 122.2 82.6 256.8 155.3 241.9 167.3 69.2 99.7 176.8 146.1 126.4 38.4 125.2 114.9 100.0 189.1 127.9 119.0 136.9 106.9 126.7 119.0 100.4 88.0 76.9 109.3 173.9 180.9 192.6 75.8 190.2 163.1 268.0 68.5 295.3 168.8 184.5 135.8 399.1 99.3 95.3 109.9 104.6 104.3 347.4 275.3 46.0 177.4 138.0 90.7 118.9 88.8 172.3 87.5 187.7 116.8 122.6 138.0 144.6 117.7 39.0 72.8 38.1 65.1 83.4 71.6 59.8 55.0 63.2 110.7 60.1 50.2 63.7 13.1 104.0 51.2 73.0 78.1 77.0 87.6 93.7 105.6 107.1 91.6 97.0 103.3 91.5 110.4 86.9 104.9 99.9 54.6 60.9 75.0 33.3 76.2 80.3 95.9 187.6 77.4 68.7 82.1 94.4 482.4 61.5 120.7 86.5 50.1 203.5 72.8 235.7 397.2 114.9 74.0 43.1 47.5 56.7 98.5 85.0 32.9 112.1 158.8 82.4 137.1 55.2 61.4 99.6 56.4 136.2 136.5 63.9 36.5 155.9 152.5 68.8 81.4 222.7 65.6 68.4 113.8 13.1 81.0 89.3 60.8 19.1 34.6 70.1 122.8 59.0 146.6 55.0 199.4 499.2 80.3 78.5 46.0 90.8 136.9 100.7 83.3 127.0 80.6 189.1 79.3 145.9 274.8 111.7 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "NEDD4 like E3 ubiquitin protein ligase" Q96PU5 18 58044226-58401540 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 253.2;Excitatory neurons: 280.9" "Cancer enhanced" "Detected in all" "prostate cancer: 29.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "T-reg: 5.1" "Lineage enriched" "Detected in many" 4 "T-cells: 5.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 146.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 11.2 16.8 20.9 6.7 34.4 27.0 25.8 25.1 31.3 7.6 0.7 38.8 18.7 5.3 10.0 12.0 9.1 9.5 26.9 32.3 16.2 53.4 36.5 47.9 4.1 10.9 18.4 6.4 60.5 13.6 28.4 12.0 10.4 64.2 42.8 20.5 27.5 20.4 34.0 11.2 33.8 6.2 8.6 7.9 51.5 7.8 16.7 4.5 17.4 13.1 7.9 19.4 5.9 16.3 70.7 24.5 14.6 20.9 5.1 2.1 49.8 19.2 88.2 48.6 74.6 28.6 37.1 15.1 57.7 7.4 51.3 50.3 19.5 86.1 100.8 34.9 15.5 10.6 14.3 111.3 2.4 0.5 6.0 13.0 54.6 66.4 78.8 39.1 4.0 13.2 18.7 6.3 20.0 16.2 1.0 1.0 12.2 26.7 33.3 14.3 20.1 17.6 47.0 88.7 17.5 5.0 16.1 5.1 146.1 28.3 29.4 5.6 28.8 131.5 38.5 7.5 83.4 8.3 15.3 9.5 27.6 10.8 10.8 0.7 0.3 1.2 0.2 0.3 0.5 0.8 0.6 0.1 0.1 0.3 0.3 0.2 0.2 0.3 0.1 0.1 5.1 0.3 20.9 34.4 25.1 31.3 32.3 16.2 10.9 18.4 10.4 8.6 16.7 16.3 6.0 253.2 144.8 110.4 5.1 112.8 161.2 34.0 86.6 18.1 99.5 65.9 47.8 64.3 112.8 62.5 173.0 13.0 3.6 144.5 49.0 35.7 22.6 64.0 7.3 14.7 45.2 57.9 280.9 49.2 4.7 9.5 114.7 75.0 3.8 4.7 17.5 41.3 7.3 62.2 173.3 201.5 101.7 8.4 8.2 6.6 3.4 13.3 14.2 88.1 7.3 45.2 2.1 11.1 105.0 49.9 145.3 17.7 12.7 126.9 127.3 91.6 72.7 10.0 0.0 34.3 6.0 1.1 12.5 62.3 53.0 80.0 6.6 8.2 72.9 155.5 NKAP FLJ22626 ENSG00000101882 "NFKB activating protein" Q8N5F7 X 119920672-119943751 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Repressor "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000916 Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA000916: AB_1079486" "prognostic unfavorable (4.20e-4)" "unprognostic (4.28e-3)" "unprognostic (9.14e-2)" "unprognostic (1.33e-3)" "unprognostic (2.66e-1)" "unprognostic (3.42e-2)" "unprognostic (3.49e-3)" "unprognostic (4.18e-3)" "unprognostic (3.70e-2)" "unprognostic (1.05e-2)" "unprognostic (1.05e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-3)" "unprognostic (1.72e-1)" "unprognostic (1.53e-2)" "unprognostic (1.45e-1)" "unprognostic (1.49e-2)" 9.5 13.1 10.6 9.8 11.5 13.6 10.6 11.8 16.2 9.2 11.1 9.8 10.3 10.6 10.7 7.3 11.0 8.9 11.0 10.5 11.6 11.3 14.5 10.5 14.4 11.9 11.5 14.1 10.1 14.2 2.7 13.5 11.4 10.4 10.1 9.6 9.9 13.5 18.2 7.4 12.7 10.3 11.2 12.5 9.3 8.5 11.0 12.7 10.1 14.4 13.0 9.7 2.4 13.0 25.0 24.3 17.6 22.3 15.3 24.7 28.9 17.7 20.4 23.4 17.2 15.9 20.9 17.6 29.9 14.6 45.8 18.3 33.7 20.6 27.9 29.6 31.2 11.1 20.6 23.3 25.1 25.2 20.4 17.9 26.4 25.1 24.7 25.3 23.2 23.8 30.6 25.5 18.4 33.8 21.4 47.0 23.6 32.4 32.8 22.8 24.3 32.7 17.5 9.6 19.2 27.2 36.8 19.7 52.3 20.9 16.8 21.1 17.4 14.8 9.0 38.4 27.4 25.4 26.7 30.2 20.4 18.9 26.1 39.7 23.5 55.6 20.8 20.0 21.6 32.2 25.4 21.2 20.6 36.6 25.6 24.3 44.5 22.2 23.1 32.5 26.6 14.3 10.6 11.5 11.8 16.2 10.5 11.6 11.9 11.5 11.4 11.2 11.0 13.0 39.9 22.4 40.4 5.2 36.1 25.9 36.1 45.5 26.7 34.0 26.2 33.3 30.3 15.7 42.3 20.2 25.0 62.5 36.0 17.5 37.2 36.7 8.8 33.6 37.4 40.3 22.8 20.6 7.2 44.3 132.0 39.1 17.9 26.7 47.4 41.6 41.4 46.3 53.0 55.5 9.0 27.9 22.4 28.0 23.2 8.9 45.1 33.9 35.6 4.7 35.3 56.3 36.0 7.5 11.0 37.5 23.3 55.3 30.6 40.3 25.8 51.3 49.4 38.5 13.1 33.4 45.0 82.7 69.6 19.6 28.7 72.9 41.5 48.3 23.1 33.7 NKX2-4 "NKX2.4, NKX2D" ENSG00000125816 "NK2 homeobox 4" Q9H2Z4 20 21395365-21397526 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 4.3;testis: 1.2" "Group enriched" "Detected in some" 24 "Cardiomyocytes: 1.3;Early spermatids: 3.0;Late spermatids: 2.7;Spermatocytes: 3.8;Spermatogonia: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "hypothalamus: 3.4;thalamus: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.5;HEK 293: 5.1;SCLC-21H: 3.2;SK-MEL-30: 4.2;WM-115: 1.2" "Region enriched" "Detected in single" 23 "hypothalamus: 2.7" "Region enriched" "Detected in single" 11 "hypothalamus: 1.1" HPA074996 Approved "Nuclear bodies" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear bodies" "HPA074996: AB_2686725" "unprognostic (3.77e-1)" "unprognostic (2.15e-1)" "unprognostic (1.68e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.0 0.0 0.0 4.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 0.1 0.2 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPIPA3 ENSG00000224712 "Nuclear pore complex interacting protein family member A3" F8WFD2 16 14708944-14726338 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Cardiomyocytes: 4.2;Respiratory ciliated cells: 2.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 4.4;hTERT-RPE1: 6.4;NB-4: 10.6;SK-MEL-30: 15.9" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (1.44e-1)" "unprognostic (7.83e-3)" "unprognostic (8.12e-3)" "unprognostic (1.87e-1)" "unprognostic (1.60e-1)" "unprognostic (5.69e-3)" "unprognostic (3.11e-2)" "unprognostic (4.58e-3)" "unprognostic (4.87e-1)" "unprognostic (2.69e-1)" "unprognostic (3.30e-2)" "unprognostic (2.04e-1)" "unprognostic (1.67e-3)" "unprognostic (1.20e-3)" "unprognostic (1.35e-1)" "unprognostic (1.79e-2)" "unprognostic (1.71e-2)" 5.1 3.6 2.0 0.8 2.0 0.7 4.7 2.8 9.4 6.6 1.5 9.3 0.2 6.8 0.8 4.4 5.8 2.5 4.4 2.2 1.7 5.5 3.8 4.7 0.4 2.0 2.0 7.7 4.0 2.5 10.7 0.5 2.1 5.8 0.9 2.0 3.1 1.0 7.4 5.8 4.1 0.4 1.7 4.0 4.7 6.5 2.0 0.1 4.7 0.3 0.4 7.2 5.4 2.1 0.0 0.6 0.1 0.3 0.0 0.1 1.4 0.5 0.0 0.4 0.4 0.0 1.9 3.3 0.2 1.2 0.7 0.1 0.1 2.1 0.2 0.1 0.0 0.3 0.7 0.4 0.2 0.1 0.5 4.4 0.7 1.2 0.1 6.4 0.1 0.6 0.1 0.2 0.2 1.2 0.0 10.6 0.8 0.0 0.0 0.1 0.0 0.0 2.9 1.0 0.4 0.4 0.0 0.2 15.9 0.6 0.2 0.0 0.5 0.5 0.1 0.0 0.0 0.0 0.2 0.1 1.7 0.1 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.0 2.8 9.4 2.2 1.7 2.0 2.0 2.1 1.7 2.0 2.1 0.2 3.2 0.5 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.2 0.1 4.2 0.0 0.7 0.0 0.0 0.1 0.0 1.2 0.0 0.1 1.1 0.1 0.1 0.8 1.2 0.0 0.1 0.2 0.1 1.2 0.0 0.1 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.6 0.0 0.7 0.6 0.1 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.2 0.0 2.4 0.0 0.0 0.3 1.0 0.5 0.3 0.0 0.0 0.3 0.3 0.0 0.7 0.1 NPPC CNP ENSG00000163273 "Natriuretic peptide C" P23582 2 231921809-231926396 "Predicted secreted proteins, Transporters" Osteogenesis "Hormone, Vasoactive" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 33.5" "Group enriched" "Detected in many" 8 "Basal squamous epithelial cells: 190.1;Skeletal myocytes: 264.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "medulla oblongata: 33.5;spinal cord: 30.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.4;NTERA-2: 3.9;SCLC-21H: 5.5;SK-MEL-30: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "medulla oblongata: 15.5;spinal cord: 12.5" HPA035362 Uncertain "Secreted to blood" NA NA 6140 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "HPA035362: AB_10671103" "unprognostic (9.70e-2)" "unprognostic (4.45e-2)" "unprognostic (1.99e-1)" "unprognostic (1.06e-2)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.83e-1)" "unprognostic (3.22e-3)" "unprognostic (9.81e-3)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" "unprognostic (4.06e-2)" "unprognostic (1.17e-1)" "unprognostic (6.58e-2)" "unprognostic (1.18e-1)" "unprognostic (3.72e-1)" "unprognostic (1.91e-1)" 0.3 0.1 0.8 2.1 0.9 1.3 0.7 2.8 3.4 1.3 0.0 4.1 0.1 0.6 0.0 3.2 2.6 0.0 5.3 2.0 3.9 0.2 0.0 0.0 1.4 33.5 4.4 1.3 0.1 0.0 2.7 0.2 4.8 4.3 0.2 2.4 1.1 0.4 0.7 0.6 0.9 0.5 30.9 0.4 2.4 0.2 4.6 2.9 0.5 0.1 2.0 0.2 0.4 6.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 1.0 0.0 3.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.5 0.3 0.2 0.2 26.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 2.8 3.4 2.0 3.9 33.5 4.4 4.8 30.9 4.6 6.5 2.1 0.0 0.0 0.7 1.3 3.4 27.1 5.9 190.1 1.1 6.5 18.3 1.9 0.0 0.1 11.0 10.4 0.2 0.6 4.2 0.0 1.1 0.3 3.6 1.3 1.6 3.5 0.0 0.0 0.0 0.0 10.9 5.6 4.8 0.0 0.3 0.0 0.0 0.1 0.0 1.5 3.2 0.0 0.0 1.7 0.0 0.3 1.6 1.8 0.0 2.5 15.2 0.0 0.0 1.3 0.8 3.1 0.0 5.8 11.5 0.0 0.0 0.0 4.1 0.0 264.2 2.0 1.2 7.0 13.2 1.1 0.3 1.7 0.0 2.9 3.1 NR4A1 "GFRP1, HMR, N10, NAK-1, NGFIB, NUR77, TR3" ENSG00000123358 "Nuclear receptor subfamily 4 group A member 1" P22736 12 52022832-52059507 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 879.9;Basal squamous epithelial cells: 729.1;Glandular and luminal cells: 739.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 36.7;non-classical monocyte: 54.2" "Lineage enriched" "Detected in many" 15 "monocytes: 54.2" "Cell line enhanced" "Detected in many" "HeLa: 78.4;MCF7: 86.9;SK-BR-3: 80.5;SK-MEL-30: 150.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059742, HPA070142" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear membrane, Cytosol" "HPA059742: AB_2684119, HPA070142: AB_2732149" "unprognostic (2.40e-2)" "unprognostic (2.57e-1)" "unprognostic (1.29e-1)" "unprognostic (1.74e-1)" "unprognostic (1.65e-1)" "unprognostic (1.16e-1)" "unprognostic (1.26e-2)" "unprognostic (1.94e-1)" "unprognostic (1.92e-2)" "unprognostic (2.22e-3)" "unprognostic (1.90e-1)" "unprognostic (1.16e-1)" "prognostic favorable (6.99e-4)" "unprognostic (3.41e-2)" "unprognostic (2.71e-1)" "unprognostic (1.84e-2)" "unprognostic (8.89e-3)" 709.0 562.0 21.7 96.9 19.6 34.5 227.6 141.0 79.9 151.6 44.4 227.1 29.7 124.6 7.2 133.6 495.8 377.4 671.5 21.5 28.5 203.5 95.5 290.9 45.9 21.8 17.4 876.0 88.4 86.9 442.4 41.9 21.0 303.2 71.4 28.3 146.5 85.9 294.1 225.7 111.9 144.2 13.0 36.0 264.6 32.4 21.5 59.1 301.7 71.9 3.8 296.5 186.0 22.6 5.7 28.2 5.6 10.2 4.0 1.3 21.3 5.4 10.8 4.3 6.0 28.2 5.4 5.9 2.3 9.7 4.2 3.2 16.9 2.6 2.5 0.3 6.0 8.1 78.4 8.3 4.1 3.1 26.5 0.8 3.3 4.2 0.3 2.9 1.3 6.6 7.9 1.4 0.3 86.9 2.2 8.5 15.3 9.2 3.1 2.7 0.9 14.6 0.2 2.2 4.6 14.0 17.4 80.5 150.9 3.8 5.1 9.1 0.0 4.2 13.3 2.8 4.7 46.8 25.2 13.0 2.8 2.3 23.7 0.3 1.3 0.0 0.2 36.7 0.3 0.9 0.1 0.1 3.7 0.8 0.5 0.1 0.4 0.2 54.2 0.3 0.2 2.0 21.7 19.6 141.0 79.9 21.5 28.5 21.8 17.4 21.0 13.0 21.5 22.6 328.9 240.4 879.9 4.2 259.5 445.7 289.5 211.3 729.1 34.8 353.8 384.9 9.8 65.8 178.4 86.5 125.1 64.5 102.1 195.7 5.9 19.9 19.7 346.9 183.5 209.6 345.3 16.0 17.4 12.3 34.7 378.8 380.7 739.1 674.8 45.3 227.0 10.1 54.1 16.8 5.9 492.5 105.8 64.4 527.4 7.3 30.4 283.0 371.8 8.4 6.3 85.4 0.0 6.6 1.3 5.1 277.2 23.7 244.1 160.6 74.6 0.9 92.6 94.6 124.9 268.0 379.3 2.5 13.4 200.2 472.8 110.5 135.1 85.1 259.0 86.8 NR4A3 "CHN, CSMF, MINOR, NOR1" ENSG00000119508 "Nuclear receptor subfamily 4 group A member 3" Q92570 9 99821855-99866891 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 305.7;Langerhans cells: 417.5;Macrophages: 172.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BJ hTERT+: 24.1;HeLa: 8.0;SK-MEL-30: 18.5;U-266/70: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043360 Uncertain NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "HPA043360: AB_10961186" "prognostic favorable (5.97e-4)" "unprognostic (6.92e-3)" "unprognostic (5.34e-2)" "unprognostic (2.78e-3)" "unprognostic (1.40e-1)" "unprognostic (9.46e-2)" "unprognostic (2.89e-2)" "unprognostic (3.30e-2)" "unprognostic (2.65e-3)" "unprognostic (1.40e-2)" "unprognostic (2.28e-1)" "unprognostic (3.30e-1)" "unprognostic (2.25e-1)" "unprognostic (1.29e-3)" "unprognostic (6.11e-2)" "unprognostic (2.80e-2)" "unprognostic (1.69e-1)" 43.2 61.2 3.4 14.9 6.3 32.7 7.4 14.1 5.5 11.4 4.2 9.8 0.7 15.7 0.7 4.0 24.8 23.5 67.2 10.2 7.4 7.8 9.0 19.6 1.3 6.3 3.9 46.8 5.2 3.0 21.2 6.5 5.9 15.6 4.0 8.7 2.4 3.3 62.8 2.4 5.8 13.4 1.1 3.5 13.7 1.0 2.9 6.5 7.2 6.2 0.9 32.8 5.1 2.3 0.1 0.1 0.7 0.1 1.3 0.4 1.1 1.5 24.1 0.2 0.2 0.2 0.1 0.2 0.3 0.7 0.5 0.1 0.5 0.0 0.1 1.8 0.3 0.1 8.0 0.0 0.2 0.1 2.3 0.3 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.5 0.1 0.7 0.0 0.2 0.0 0.2 0.6 0.0 1.1 0.0 0.0 0.1 0.4 0.4 2.7 2.0 18.5 0.2 0.0 0.0 0.1 1.4 0.4 1.8 0.1 9.2 0.1 0.0 0.9 0.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.4 6.3 14.1 5.5 10.2 7.4 6.3 3.9 5.9 1.1 2.9 2.3 9.6 12.8 19.7 3.9 101.5 79.5 14.0 3.5 97.9 0.9 44.2 58.5 305.7 4.3 10.0 16.5 10.4 2.3 91.3 2.0 0.0 0.1 1.4 93.1 12.8 16.2 27.3 0.4 13.1 1.7 2.2 60.3 32.6 124.3 120.7 1.2 7.5 0.5 10.5 0.0 6.2 3.8 2.0 12.3 417.5 2.4 1.5 172.8 88.9 2.8 43.0 3.6 1.0 1.5 0.9 0.2 2.3 1.2 37.9 4.7 0.6 0.1 11.4 1.7 0.0 35.7 75.0 1.1 1.6 15.9 59.5 5.6 69.6 1.0 1.7 3.4 NRG3 ENSG00000185737 "Neuregulin 3" P56975 10 81875194-82987179 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.3;retina: 5.2" "Group enriched" "Detected in some" 18 "Astrocytes: 2921.6;Excitatory neurons: 3761.0;Inhibitory neurons: 3088.3;Oligodendrocyte precursor cells: 1175.2" "Cancer enhanced" "Detected in many" "melanoma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SK-MEL-30: 2.7;U-2 OS: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075789 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA075789: " "unprognostic (6.15e-3)" "unprognostic (2.43e-2)" "unprognostic (1.65e-5)" "unprognostic (1.89e-1)" "unprognostic (7.03e-4)" "unprognostic (1.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-2)" "unprognostic (3.31e-4)" "unprognostic (1.04e-1)" "unprognostic (7.68e-3)" "unprognostic (7.27e-4)" 0.1 0.4 16.4 0.3 11.4 0.0 1.3 0.0 17.3 0.1 0.0 0.4 0.1 0.0 0.0 0.1 4.7 2.8 0.4 16.1 2.6 0.7 0.5 0.7 0.1 1.2 6.3 0.0 0.1 0.1 2.0 0.3 0.4 0.1 0.1 5.2 2.6 0.2 0.0 0.6 0.1 0.1 2.5 0.1 0.3 1.8 9.9 0.0 0.2 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 11.4 0.0 17.3 16.1 2.6 1.2 6.3 0.4 2.5 9.9 3.5 0.1 0.0 0.0 2921.6 0.1 0.0 0.0 0.0 0.0 15.9 0.7 0.6 0.8 2.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.9 31.4 0.0 0.0 0.7 0.0 0.0 3761.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3088.3 0.0 0.0 0.0 0.0 12.8 0.6 0.1 0.0 148.0 0.0 6.7 0.0 1175.2 50.2 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 OCA2 "BEY, BEY1, BEY2, D15S12, EYCL, EYCL2, EYCL3, P" ENSG00000104044 "OCA2 melanosomal transmembrane protein" Q04671 15 27754875-28099315 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Albinism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 28.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 30.9;Inhibitory neurons: 40.8;Melanocytes: 42.7;Peritubular cells: 14.7" "Cancer enriched" "Detected in many" 17 "melanoma: 19.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SK-MEL-30: 24.6" "Low region specificity" "Detected in some" HPA036402 Approved "Plasma membrane,Cytosol" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Cytosol "HPA036402: " "unprognostic (6.07e-3)" "unprognostic (1.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.82e-2)" "unprognostic (4.60e-4)" "unprognostic (7.11e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.47e-2)" "unprognostic (4.95e-2)" "unprognostic (1.96e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-6)" "unprognostic (2.61e-1)" "unprognostic (4.21e-1)" "unprognostic (3.28e-2)" "unprognostic (2.28e-2)" 0.3 0.0 1.8 0.1 1.8 0.0 0.3 0.1 1.8 1.2 28.1 0.1 0.0 0.2 0.3 2.2 1.1 0.0 0.3 1.4 1.8 0.3 0.1 0.6 1.8 0.5 0.9 0.3 0.0 0.0 0.8 1.5 0.6 0.6 0.0 0.0 0.8 1.0 0.2 6.4 0.2 0.0 0.0 1.1 0.1 1.9 2.4 0.4 4.2 0.0 0.7 0.2 2.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.1 5.6 0.0 0.0 24.6 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 0.1 1.8 1.4 1.8 0.5 0.9 0.6 0.0 2.4 1.0 0.0 0.0 0.0 0.7 0.0 2.0 0.1 0.1 0.6 0.0 0.0 0.4 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.4 5.6 0.2 0.1 0.0 0.0 30.9 0.0 0.1 1.4 0.0 2.8 0.0 2.3 0.0 0.0 0.1 0.0 40.8 0.1 0.0 0.0 0.9 3.0 9.3 0.1 42.7 0.0 0.0 0.0 0.0 2.5 0.8 0.0 1.2 14.7 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.8 4.2 4.9 6.1 0.9 0.1 0.1 0.4 0.1 0.2 OSGEPL1 "OSGEPL, Qri7" ENSG00000128694 "O-sialoglycoprotein endopeptidase like 1" Q9H4B0 2 189746660-189763227 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030693 Uncertain Supported Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA030693: AB_10601978" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (8.19e-2)" "unprognostic (6.70e-2)" "unprognostic (6.07e-2)" "unprognostic (6.38e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (4.18e-3)" "unprognostic (1.06e-3)" "prognostic favorable (3.19e-4)" "unprognostic (2.33e-1)" "unprognostic (1.80e-2)" "unprognostic (3.34e-2)" "unprognostic (2.68e-1)" "unprognostic (1.51e-2)" "unprognostic (6.39e-2)" "unprognostic (1.55e-3)" 3.9 8.2 3.6 3.5 5.0 1.9 7.2 6.1 5.0 4.5 3.0 3.5 3.3 5.7 5.6 4.0 5.2 3.2 8.9 3.4 4.0 8.4 7.9 3.9 6.5 4.3 4.5 8.7 3.1 4.7 2.7 4.0 4.5 4.1 3.9 9.8 4.7 3.7 12.3 6.1 3.5 5.0 4.3 5.4 3.1 6.4 3.9 5.6 5.2 11.0 6.3 3.6 3.0 6.1 7.1 3.8 16.7 12.7 12.9 7.1 9.8 10.8 7.5 14.9 15.9 4.5 7.1 4.7 11.7 4.5 8.2 10.1 15.0 12.7 16.9 12.3 11.5 15.3 9.0 5.9 6.7 8.8 7.6 7.8 10.6 11.5 5.5 10.2 11.3 11.8 5.6 7.2 9.8 3.9 6.8 9.9 8.1 9.5 17.4 7.5 13.4 8.1 9.7 3.8 10.1 11.2 7.3 12.8 23.9 20.6 10.1 9.9 4.7 9.6 8.5 14.3 6.8 7.3 6.6 7.4 12.7 11.0 10.7 0.5 2.7 2.3 7.5 2.7 10.6 7.7 7.7 8.6 3.8 9.8 11.3 10.5 0.4 7.6 2.4 6.6 6.6 3.1 3.6 5.0 6.1 5.0 3.4 4.0 4.3 4.5 4.5 4.3 3.9 6.1 3.6 6.4 3.6 6.8 8.4 1.9 2.8 5.9 5.2 8.9 4.0 4.8 8.6 8.6 2.8 0.0 12.5 10.6 7.3 0.4 7.9 3.0 1.4 3.5 5.5 4.1 0.0 5.2 6.6 2.3 7.3 4.5 1.5 2.3 3.8 6.8 3.6 2.9 4.4 10.1 10.0 1.1 2.0 2.4 1.7 0.8 11.1 4.1 1.8 5.6 1.8 12.0 13.4 10.1 17.0 2.0 1.0 8.2 1.9 1.1 1.7 10.2 6.0 11.8 26.3 5.8 8.4 9.6 13.7 4.4 2.0 2.2 6.0 11.8 2.2 1.0 P2RX4 P2X4 ENSG00000135124 "Purinergic receptor P2X 4" Q99571 12 121209861-121234106 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 135.3;Distal enterocytes: 133.7;Hofbauer cells: 129.5;Syncytiotrophoblasts: 155.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039494 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA039494: AB_10969132" "unprognostic (4.02e-3)" "unprognostic (1.06e-1)" "unprognostic (5.43e-2)" "prognostic favorable (6.30e-10)" "unprognostic (2.98e-2)" "unprognostic (2.52e-1)" "unprognostic (2.06e-3)" "unprognostic (1.68e-1)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (7.71e-2)" "unprognostic (2.18e-1)" "unprognostic (1.81e-2)" "unprognostic (1.13e-1)" "unprognostic (6.06e-2)" "unprognostic (1.42e-2)" "unprognostic (4.76e-3)" 10.1 9.9 4.8 15.1 5.0 14.1 12.7 8.3 5.6 18.8 4.6 33.5 28.9 8.5 3.7 5.0 15.3 16.8 7.2 5.1 5.3 13.0 11.5 20.4 15.9 6.7 5.4 18.1 37.4 33.1 5.1 32.7 6.0 12.1 30.2 2.0 30.1 12.0 1.0 4.5 32.8 10.7 6.3 12.6 20.2 6.0 6.3 7.8 12.9 2.3 8.9 12.1 4.1 7.6 6.6 15.4 1.1 21.7 10.3 8.3 40.6 4.9 26.1 6.7 13.3 10.9 23.1 6.4 18.5 17.4 48.2 2.3 4.7 3.2 4.1 17.5 11.8 3.1 0.9 12.5 25.3 7.6 42.5 11.9 6.8 11.0 14.5 20.4 24.2 7.7 6.1 16.2 5.0 31.8 4.7 10.7 5.5 31.8 10.5 6.6 29.5 34.6 3.1 18.0 6.1 9.0 16.0 8.8 55.0 5.7 38.5 21.2 2.1 10.0 11.2 1.2 5.2 28.0 26.1 3.7 19.6 10.2 9.1 72.3 59.1 10.7 13.6 63.1 15.1 11.3 21.9 13.3 32.5 7.1 16.4 9.6 0.8 29.6 54.6 4.4 17.1 32.6 4.8 5.0 8.3 5.6 5.1 5.3 6.7 5.4 6.0 6.3 6.3 7.6 8.4 6.4 19.2 6.5 14.0 3.8 8.9 11.9 6.8 11.1 17.7 11.9 3.8 21.5 11.2 20.2 2.1 135.3 13.7 133.7 0.0 69.7 15.2 9.8 8.9 9.2 21.5 2.1 6.4 35.4 73.8 14.3 19.4 15.1 13.9 14.3 23.6 9.4 129.5 15.2 5.3 90.3 20.3 43.7 20.8 25.1 8.7 53.7 10.6 18.7 57.9 6.5 19.6 4.5 8.0 33.1 80.6 9.8 21.9 10.2 98.7 23.2 6.4 8.6 19.7 7.4 12.0 8.1 6.6 3.4 4.0 155.7 17.8 15.4 24.7 9.7 P2RX7 "MGC20089, P2X7" ENSG00000089041 "Purinergic receptor P2X 7" Q99572 12 121132819-121188032 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.8;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 156.7" "Group enriched" "Detected in all" 5 "glioma: 7.2;melanoma: 19.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 2.9;gdT-cell: 1.3;intermediate monocyte: 4.5;myeloid DC: 2.6;non-classical monocyte: 3.3;T-reg: 1.4" "Group enriched" "Detected in many" 5 "dendritic cells: 2.6;monocytes: 4.5;T-cells: 1.4" "Cell line enhanced" "Detected in many" "Karpas-707: 40.0;RPMI-8226: 24.8;SK-MEL-30: 41.0;U-266/70: 21.7;U-266/84: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034968, HPA042013, HPA044141" Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA034968: AB_10673105, HPA042013: AB_2677797, HPA044141: AB_2678830" "unprognostic (1.05e-1)" "unprognostic (4.90e-2)" "unprognostic (8.87e-2)" "unprognostic (6.54e-3)" "unprognostic (4.49e-2)" "unprognostic (1.55e-2)" "unprognostic (8.82e-2)" "unprognostic (9.11e-2)" "unprognostic (1.05e-2)" "unprognostic (1.08e-1)" "unprognostic (2.42e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.91e-1)" "unprognostic (3.59e-2)" "unprognostic (5.55e-2)" "unprognostic (1.65e-1)" 2.8 2.5 20.2 5.1 28.5 2.9 2.0 23.1 30.7 6.1 11.3 3.6 1.5 4.1 1.5 1.4 2.3 3.5 1.3 21.8 20.7 0.7 4.6 6.5 5.9 26.3 24.7 8.3 1.4 1.7 1.8 2.9 28.3 1.8 2.3 0.5 2.5 1.8 0.6 13.1 1.8 4.2 21.3 5.9 1.6 1.3 26.2 1.7 1.0 1.0 3.6 2.3 4.4 47.3 0.1 0.0 0.0 1.0 1.1 0.4 0.8 0.1 1.9 0.7 1.7 0.0 0.0 0.1 0.1 0.7 4.3 0.2 0.0 0.0 0.5 1.8 0.1 0.7 0.0 0.1 0.8 1.6 11.6 1.0 0.0 2.0 0.0 0.0 1.9 0.4 0.0 40.0 0.0 0.0 0.2 4.4 0.1 0.0 0.4 3.8 8.9 24.8 0.0 0.0 0.5 2.3 0.2 0.0 41.0 0.0 0.6 7.8 0.0 0.6 0.1 0.1 0.2 21.7 20.2 0.1 2.4 11.8 6.1 0.4 2.9 0.0 1.3 4.5 0.5 0.3 0.6 0.6 2.6 0.2 0.5 0.6 0.3 0.6 3.3 0.4 1.4 0.9 20.2 28.5 23.1 30.7 21.8 20.7 26.3 24.7 28.3 21.3 26.2 47.3 2.0 3.2 4.8 12.1 3.9 6.9 3.0 0.0 1.8 3.9 1.8 2.2 2.4 5.7 3.7 0.0 2.1 3.5 9.0 1.2 0.0 1.2 0.6 0.7 1.6 3.9 0.0 1.7 52.8 0.0 0.9 3.7 0.0 0.3 6.3 2.6 5.3 3.9 23.4 1.7 18.4 0.2 0.0 21.5 35.0 1.5 11.1 34.2 16.0 34.7 21.2 1.3 7.2 87.9 156.7 0.2 0.0 10.5 1.3 1.2 0.1 0.0 3.6 1.0 6.6 3.2 1.9 1.2 0.9 1.0 3.7 4.0 6.6 4.1 0.1 1.0 PAAF1 "FLJ11848, Rpn14, WDR71" ENSG00000175575 "Proteasomal ATPase associated factor 1" Q9BRP4 11 73876699-73931114 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 130.1" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 112.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039952, HPA040020" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA039952: AB_10793925, HPA040020: AB_2676802" "unprognostic (3.13e-1)" "unprognostic (1.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-1)" "unprognostic (2.05e-1)" "unprognostic (2.13e-2)" "unprognostic (4.51e-2)" "unprognostic (1.33e-1)" "unprognostic (4.58e-3)" "unprognostic (1.74e-1)" "unprognostic (4.48e-1)" "unprognostic (2.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.23e-1)" "unprognostic (2.73e-1)" "unprognostic (4.42e-1)" 17.3 29.0 85.2 11.3 92.6 9.0 17.6 82.3 130.1 19.4 68.8 25.0 11.8 16.6 23.8 14.4 19.6 12.0 25.2 80.3 85.9 23.9 21.9 12.6 12.6 88.0 88.6 24.6 22.2 19.1 25.8 11.7 87.3 22.0 16.3 46.4 15.4 19.8 19.8 19.2 14.3 15.5 85.4 16.3 18.5 30.3 85.7 15.9 18.8 7.5 17.2 21.7 16.3 101.2 13.5 30.6 27.2 21.3 28.9 29.6 15.5 22.6 25.9 35.3 25.0 60.2 10.4 40.4 34.4 23.2 32.8 30.2 33.5 27.2 52.2 30.4 20.8 41.4 28.0 50.3 34.6 39.1 15.3 30.5 41.7 38.8 47.2 28.4 27.0 32.1 50.7 33.7 33.2 26.3 34.5 40.5 12.7 71.0 23.7 31.6 72.6 66.5 26.5 22.9 28.8 33.8 26.8 17.7 70.6 25.4 53.1 21.8 19.7 24.8 15.7 35.3 22.3 41.3 50.3 82.2 17.4 25.0 26.5 53.4 26.2 32.3 26.8 17.2 29.5 40.8 28.7 27.3 34.4 36.1 37.0 31.7 2.2 32.4 6.3 24.8 36.8 27.9 85.2 92.6 82.3 130.1 80.3 85.9 88.0 88.6 87.3 85.4 85.7 101.2 9.0 3.2 12.5 40.1 11.5 4.7 11.6 27.3 6.8 50.4 6.8 9.1 19.6 8.6 15.6 16.5 112.6 33.5 9.5 5.5 13.7 15.9 38.4 10.7 12.2 9.8 3.6 20.2 17.4 13.8 4.8 11.5 6.6 9.4 19.6 30.1 11.7 13.6 18.8 47.1 23.7 7.7 20.3 9.5 6.6 22.6 16.8 9.5 14.2 14.0 16.3 37.6 18.6 24.6 55.5 7.3 5.7 18.0 15.3 9.6 12.0 53.5 14.1 51.7 6.6 18.2 12.5 48.9 28.6 9.6 8.1 18.3 9.8 29.9 10.3 8.0 PACSIN2 SDPII ENSG00000100266 "Protein kinase C and casein kinase substrate in neurons 2" Q9UNF0 22 42835412-43015149 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 95.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049854, HPA056520" Enhanced Supported "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA 2400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles, Vesicles, Cytosol" "Plasma membrane" "HPA049854: AB_2680915, HPA056520: AB_2683163" "unprognostic (5.62e-3)" "unprognostic (1.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-3)" "unprognostic (1.63e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (7.33e-4)" "unprognostic (4.48e-2)" "unprognostic (3.40e-2)" "unprognostic (2.82e-3)" "unprognostic (3.09e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.09e-13)" "unprognostic (2.87e-1)" "unprognostic (1.11e-1)" "unprognostic (6.20e-2)" "unprognostic (2.95e-1)" 40.8 74.3 25.7 37.1 29.1 29.3 40.7 34.2 27.3 37.5 32.3 61.7 40.8 39.1 21.2 34.1 35.3 45.3 55.7 27.7 39.2 47.1 41.1 50.9 34.2 40.5 36.8 31.4 162.4 29.4 39.9 34.2 40.8 47.0 41.6 28.2 43.5 27.4 49.8 39.5 38.1 30.4 30.7 35.9 51.5 19.5 32.5 28.7 43.9 42.4 26.4 36.5 34.5 31.1 76.3 78.3 64.6 41.5 32.6 34.6 52.9 67.8 40.7 59.9 49.7 82.1 43.8 35.2 56.1 50.6 40.8 52.8 42.5 72.1 39.3 36.1 42.4 56.8 39.4 117.8 46.1 40.5 118.1 33.4 69.8 79.1 34.3 48.7 49.9 32.1 49.9 24.9 52.2 49.7 43.1 63.3 35.6 110.4 32.7 52.3 96.5 23.8 68.9 44.4 41.9 18.7 81.1 55.2 155.8 41.5 40.1 53.1 74.3 44.5 56.4 50.0 40.5 18.4 27.2 38.4 42.7 35.4 99.1 26.1 18.5 47.4 6.8 32.2 7.3 11.3 7.8 5.8 21.5 11.6 7.6 5.8 95.7 16.8 33.9 7.9 12.1 14.1 25.7 29.1 34.2 27.3 27.7 39.2 40.5 36.8 40.8 30.7 32.5 31.1 31.7 70.5 60.6 20.2 20.6 23.2 43.4 23.9 21.1 15.7 37.4 31.1 26.3 24.3 37.2 46.0 39.6 34.4 19.9 142.6 45.0 80.2 3.6 51.6 31.3 28.6 24.7 12.6 22.7 65.4 29.6 20.9 36.7 57.4 71.0 14.7 16.1 22.3 42.7 6.7 41.0 49.5 30.5 38.5 50.0 6.2 21.8 44.9 83.6 54.4 51.3 8.4 7.2 29.1 19.5 70.9 62.3 23.3 13.1 50.6 32.0 55.0 30.7 24.9 92.1 23.5 82.9 22.6 27.6 22.5 16.9 48.2 19.1 13.8 42.2 30.3 PAEP "GD, GdA, GdF, GdS, MGC138509, MGC142288, PAEG, PEP, PP14" ENSG00000122133 "Progestagen associated endometrial protein" P09466 9 135561756-135566955 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 94.1;endometrium 1: 256.0" "Cell type enriched" "Detected in some" 10 "Glandular and luminal cells: 10785.5" "Cancer enriched" "Detected in many" 8 "melanoma: 275.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.1;neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.1" "Cell line enriched" "Detected in some" 7 "SK-MEL-30: 21.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016762, HPA020108, HPA029473" Enhanced "Secreted in female reproductive system" NA NA 120000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "CAB016762: , HPA020108: AB_1855595, HPA029473: AB_10610147" "unprognostic (3.39e-2)" "unprognostic (8.47e-3)" "unprognostic (6.84e-2)" "unprognostic (3.46e-2)" "unprognostic (3.20e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (1.27e-2)" "unprognostic (1.72e-1)" "unprognostic (3.95e-3)" "unprognostic (1.93e-3)" "prognostic unfavorable (0.00e+0)" "prognostic unfavorable (5.46e-4)" "unprognostic (4.24e-1)" "unprognostic (4.98e-2)" 0.1 0.2 0.2 1.1 0.4 1.6 0.5 0.7 0.7 94.1 2.0 0.1 1.0 256.0 0.9 0.2 4.8 0.3 0.1 0.4 0.4 0.1 0.1 0.5 0.6 0.3 0.2 0.7 0.0 0.0 0.0 27.2 0.2 2.7 0.1 0.4 0.4 44.8 0.6 2.1 0.8 0.1 0.1 0.3 6.0 0.7 0.4 0.0 0.3 0.0 0.1 0.3 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.0 0.9 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.6 1.6 2.2 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.2 2.9 0.2 0.0 0.3 0.0 0.7 0.5 0.0 0.0 0.2 0.2 0.3 0.0 0.2 0.4 0.2 0.1 0.2 21.0 0.6 0.3 0.2 0.0 0.0 1.0 0.2 0.1 0.8 2.2 0.1 0.2 0.2 0.2 3.1 0.3 0.2 0.2 0.2 0.1 0.2 0.3 0.2 0.1 0.4 0.3 0.3 1.4 0.3 0.3 0.5 0.1 0.1 0.2 0.4 0.7 0.7 0.4 0.4 0.3 0.2 0.2 0.1 0.4 1.0 0.0 0.0 0.5 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.9 0.6 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 613.5 1008.8 67.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 10785.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 144.0 0.0 0.0 0.0 0.0 0.0 86.5 0.0 0.0 0.0 PAIP2 PAIP2A ENSG00000120727 "Poly(A) binding protein interacting protein 2" Q9BPZ3 5 139341587-139369720 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 834.4;Late spermatids: 2779.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035945, CAB037212, HPA056766" Approved Supported Vesicles NA NA 21000 "Cluster 5: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB037212: AB_1841072, HPA035945: AB_10672996, HPA056766: AB_2683231" "unprognostic (1.07e-1)" "unprognostic (1.44e-1)" "unprognostic (1.19e-1)" "unprognostic (5.86e-2)" "unprognostic (7.40e-2)" "unprognostic (3.80e-3)" "unprognostic (7.70e-3)" "unprognostic (8.91e-2)" "unprognostic (4.64e-2)" "unprognostic (2.36e-2)" "unprognostic (2.67e-2)" "unprognostic (3.27e-1)" "unprognostic (2.01e-3)" "unprognostic (2.01e-1)" "unprognostic (2.21e-1)" "unprognostic (3.36e-1)" "unprognostic (6.92e-2)" 103.3 148.6 107.9 77.2 107.9 115.7 90.3 120.0 149.6 77.3 119.9 79.1 44.2 94.1 85.6 68.8 91.6 66.5 173.1 107.8 118.9 104.7 114.2 73.1 109.0 119.5 114.0 112.3 64.2 88.9 96.2 93.7 123.8 84.3 53.9 168.9 92.1 82.4 169.6 48.2 50.0 83.1 119.1 92.1 58.1 169.0 110.0 147.4 74.6 161.9 107.7 81.4 54.3 138.9 91.9 102.7 196.2 118.5 144.0 81.3 95.6 81.9 113.6 104.7 163.6 138.5 86.7 160.7 170.8 62.3 120.1 88.9 173.5 112.5 137.4 155.7 136.4 148.5 145.7 125.8 93.0 92.8 105.4 93.2 92.4 78.5 88.8 112.9 108.7 173.3 143.7 138.6 95.8 121.1 254.3 227.3 118.9 130.5 74.6 140.0 248.1 177.2 84.0 163.2 90.9 165.2 121.2 110.7 251.2 245.4 214.4 192.6 66.9 55.9 67.9 61.3 67.3 200.0 262.6 167.8 98.2 161.6 58.9 569.5 292.2 735.8 286.2 329.3 317.0 378.7 314.7 330.4 292.0 337.7 364.4 356.5 800.5 347.5 380.6 298.7 449.5 577.2 107.9 107.9 120.0 149.6 107.8 118.9 119.5 114.0 123.8 119.1 110.0 138.9 154.8 73.7 87.5 26.4 173.8 159.8 164.3 168.2 79.1 102.4 108.2 98.0 59.7 97.2 100.9 99.3 58.4 198.6 253.1 74.0 170.2 126.4 834.4 228.6 109.2 126.9 97.0 190.0 40.6 115.1 134.1 129.5 38.7 109.0 109.0 108.2 123.1 103.8 142.3 97.6 46.6 57.7 120.1 142.2 196.1 2779.9 160.9 170.6 135.2 29.0 239.2 158.5 247.2 29.7 59.9 122.5 64.7 155.3 146.8 232.8 62.1 256.2 149.4 93.6 170.9 87.7 180.3 432.3 238.1 57.0 208.3 479.7 191.3 145.8 59.5 178.3 PANK2 "C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN" ENSG00000125779 "Pantothenate kinase 2" Q9BZ23 20 3888839-3929887 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Coenzyme A biosynthesis" "Kinase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008440 Approved Supported Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA008440: AB_1079559" "unprognostic (4.50e-2)" "unprognostic (7.96e-3)" "unprognostic (2.26e-1)" "unprognostic (1.39e-2)" "unprognostic (1.68e-1)" "unprognostic (6.00e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (2.75e-1)" "unprognostic (3.39e-1)" "unprognostic (2.52e-1)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" "unprognostic (6.01e-3)" "unprognostic (1.73e-2)" "unprognostic (2.18e-3)" "unprognostic (2.63e-1)" "unprognostic (1.81e-1)" 13.0 12.3 14.5 16.8 13.7 20.9 12.2 15.3 15.9 11.9 14.1 11.4 8.4 11.0 11.3 20.0 16.3 12.1 8.7 15.5 13.5 15.7 18.3 14.1 18.5 12.7 14.1 12.9 10.3 10.9 8.9 15.3 13.3 12.0 14.2 10.3 11.9 10.7 9.6 11.7 11.6 13.7 12.7 14.9 9.1 25.9 13.9 16.8 15.4 11.2 22.0 15.6 9.9 12.4 39.3 29.4 33.7 18.6 39.3 32.6 15.0 25.6 34.2 38.3 48.3 40.8 25.4 34.6 10.6 34.9 70.2 34.9 34.7 57.3 49.3 8.8 9.8 47.4 22.7 80.2 33.3 33.6 15.9 28.7 26.4 39.7 28.7 17.0 36.0 23.3 34.7 30.5 42.5 11.7 30.0 30.3 28.8 22.9 19.5 20.3 46.0 22.4 26.2 45.7 36.2 16.7 30.0 44.3 78.1 32.6 23.6 28.1 24.6 47.7 17.8 60.7 43.3 14.0 50.8 23.3 15.0 30.7 34.2 3.0 10.5 3.4 3.6 11.1 3.5 3.8 3.7 3.4 8.5 4.5 4.1 3.4 5.9 6.8 9.4 3.0 5.9 4.0 14.5 13.7 15.3 15.9 15.5 13.5 12.7 14.1 13.3 12.7 13.9 12.4 23.8 19.2 11.7 23.8 29.2 25.5 17.5 12.0 41.5 22.0 15.8 17.3 9.8 7.2 13.4 14.7 25.0 29.4 38.6 14.4 23.5 19.4 83.1 24.1 20.6 26.7 20.3 42.7 28.6 17.8 36.0 21.1 24.5 24.1 7.6 20.1 26.0 14.0 33.8 35.3 25.3 12.7 10.2 52.8 37.9 17.3 21.1 34.3 19.6 29.0 55.0 14.1 35.0 23.1 17.7 15.9 12.8 22.6 33.2 20.9 15.1 20.6 20.2 21.1 6.6 14.1 23.1 54.6 25.9 37.7 24.3 18.6 31.6 21.2 15.0 20.0 PAX3 "HUP2, WS1" ENSG00000135903 "Paired box 3" P23760 2 222199887-222298998 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Deafness, Disease variant, Proto-oncogene, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;salivary gland: 4.8;skeletal muscle: 3.6;skin 1: 2.9" "Group enriched" "Detected in some" 4 "Early spermatids: 14.4;Late spermatids: 34.8;Melanocytes: 33.8;Skeletal myocytes: 12.8" "Cancer enriched" "Detected in some" 24 "melanoma: 20.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 9.0;BJ hTERT+ SV40 Large T+ RasG12V: 10.6;HBF TERT88: 8.0;RH-30: 17.5;SK-MEL-30: 29.1" "Group enriched" "Detected in some" 7 "cerebellum: 3.4;midbrain: 1.4;pons and medulla: 1.3" "Region enhanced" "Detected in many" "midbrain: 7.7" "HPA063659, HPA069000" Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA063659: AB_2685080, HPA069000: AB_2686067" "unprognostic (2.57e-2)" "unprognostic (1.48e-2)" "unprognostic (1.27e-2)" "unprognostic (1.65e-1)" "unprognostic (2.61e-2)" "unprognostic (3.70e-1)" "unprognostic (6.18e-2)" "unprognostic (1.41e-1)" "unprognostic (2.26e-1)" "unprognostic (9.70e-2)" 0.5 0.0 0.4 0.0 0.1 0.0 1.0 4.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.3 1.9 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 4.8 0.0 3.6 2.9 0.0 0.0 2.0 0.0 0.0 1.1 1.2 0.0 0.0 0.8 0.1 0.0 0.1 5.5 0.0 0.0 4.9 0.0 0.0 0.0 0.0 6.0 6.5 9.0 10.6 0.0 0.7 0.0 0.0 4.4 0.2 0.0 0.0 0.0 8.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 6.9 0.1 0.0 0.0 0.0 17.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 29.1 7.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 3.5 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 4.6 0.1 0.0 0.1 3.3 1.9 2.8 2.0 1.2 5.5 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.2 0.0 0.0 2.9 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.8 34.8 0.9 0.1 33.8 1.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.4 5.6 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 PCDHA7 "CNR4, CNRS4, CRNR4" ENSG00000204963 "Protocadherin alpha 7" Q9UN72 5 140834248-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 3.0" "Cell type enhanced" "Detected in some" "Horizontal cells: 1.7;Spermatocytes: 1.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.0;SK-MEL-30: 1.2;WM-115: 1.1" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.99e-1)" "unprognostic (8.54e-2)" "unprognostic (2.67e-1)" "unprognostic (5.28e-2)" "unprognostic (3.05e-1)" "unprognostic (7.08e-2)" "unprognostic (9.29e-3)" "unprognostic (4.11e-3)" "unprognostic (7.20e-2)" "unprognostic (3.18e-3)" "unprognostic (3.12e-4)" "unprognostic (9.54e-4)" "unprognostic (6.86e-5)" "unprognostic (5.34e-4)" "unprognostic (2.88e-1)" "unprognostic (3.72e-1)" "unprognostic (1.14e-1)" 0.2 0.1 0.4 0.0 0.4 0.0 0.2 3.0 0.9 0.2 0.0 0.2 0.1 0.3 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.3 0.0 0.2 0.0 1.0 0.4 0.3 0.3 0.1 0.4 0.0 0.6 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.9 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.8 1.2 0.3 0.2 0.0 0.1 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 3.0 0.9 0.3 0.0 1.0 0.4 0.6 0.3 0.0 1.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.4 0.0 0.0 0.2 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 "Protocadherin gamma subfamily A, 11" Q9Y5H2 5 141421047-141512975 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Bipolar cells: 2.5;Hepatic stellate cells: 1.1;Horizontal cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.3;ASC TERT1: 25.9;GAMG: 47.4;hTERT-RPE1: 69.8;WM-115: 43.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.13e-2)" "unprognostic (1.78e-3)" "unprognostic (9.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.68e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.16e-3)" "unprognostic (1.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.97e-1)" "unprognostic (2.22e-1)" "unprognostic (3.03e-2)" "unprognostic (3.74e-2)" "unprognostic (3.54e-1)" "unprognostic (4.34e-3)" "unprognostic (1.89e-1)" 0.8 0.7 1.4 0.7 1.8 0.0 0.6 5.1 1.3 0.8 0.7 1.0 0.2 0.7 0.3 0.7 0.9 0.5 1.6 2.1 2.3 0.5 0.4 0.6 0.4 1.8 1.2 1.1 0.5 0.3 0.6 2.2 2.1 0.5 0.3 3.1 0.7 0.7 1.1 1.7 0.4 0.8 2.4 0.3 0.4 0.8 1.9 0.3 0.8 0.5 0.3 0.6 0.8 2.9 0.0 0.0 0.7 2.4 24.3 25.9 0.9 5.5 10.6 4.2 6.6 0.1 0.2 0.6 9.1 5.6 47.4 3.7 0.1 0.6 6.6 0.2 2.4 0.1 0.1 0.0 4.0 0.4 0.0 19.0 0.3 7.4 0.1 69.8 6.5 1.2 0.0 0.1 0.1 0.0 0.0 0.3 2.9 0.0 0.1 17.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 21.3 9.9 0.5 3.2 7.9 0.8 0.1 0.6 0.1 0.0 0.4 0.0 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 1.8 5.1 1.3 2.1 2.3 1.8 1.2 2.1 2.4 1.9 2.9 0.5 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 2.5 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.1 0.5 0.8 0.0 0.0 0.0 0.2 0.3 0.5 0.0 0.1 0.0 0.2 1.1 0.0 0.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.6 0.3 0.1 0.1 0.7 0.0 0.1 0.0 0.2 0.1 0.1 PET117 CSRP2BP ENSG00000232838 "PET117 cytochrome c oxidase chaperone" Q6UWS5 20 18137863-18143169 "Disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" HPA047716 Approved "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA047716: AB_2680128" "unprognostic (1.34e-2)" "unprognostic (2.83e-1)" "unprognostic (3.94e-1)" "unprognostic (2.02e-1)" "unprognostic (2.39e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (4.76e-6)" "unprognostic (7.74e-2)" "unprognostic (1.25e-1)" "unprognostic (3.13e-2)" "unprognostic (4.90e-1)" "unprognostic (2.78e-1)" "prognostic favorable (4.15e-4)" "unprognostic (3.73e-1)" "unprognostic (4.63e-1)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" 8.7 16.8 12.5 5.5 13.0 8.0 8.5 12.8 17.8 8.4 13.5 12.2 15.6 9.9 10.4 8.0 8.5 5.1 12.9 12.6 12.9 14.1 12.5 8.0 6.0 12.7 12.4 10.0 11.4 9.7 11.8 7.4 13.0 9.3 9.4 9.7 10.4 6.5 22.9 10.8 10.9 5.8 12.8 8.6 16.5 7.2 12.8 4.5 8.9 9.6 5.3 9.5 7.6 13.8 33.0 28.7 10.4 10.6 14.9 11.3 29.8 16.8 16.5 19.6 18.2 26.5 26.7 19.5 27.0 16.1 34.9 17.6 19.0 31.5 20.5 4.4 20.9 21.9 19.2 63.8 24.6 29.2 23.2 17.8 17.1 19.3 20.1 15.7 15.7 23.3 18.6 17.1 14.3 26.8 17.1 33.5 15.4 35.2 31.8 15.3 33.4 35.0 21.2 19.4 18.9 18.6 23.1 43.0 46.9 27.1 26.2 21.3 15.0 17.7 13.7 19.0 29.4 24.4 41.8 31.5 8.8 9.5 16.3 3.4 24.9 11.4 18.3 23.3 20.7 26.2 22.7 23.0 22.0 23.2 31.6 24.2 1.5 21.0 29.7 41.0 20.4 15.8 12.5 13.0 12.8 17.8 12.6 12.9 12.7 12.4 13.0 12.8 12.8 13.8 10.3 19.2 10.6 0.3 11.4 3.8 16.7 17.2 8.0 16.9 13.5 14.6 13.7 35.8 16.3 16.5 4.2 29.8 12.4 15.4 33.2 21.8 1.0 12.3 8.8 9.1 15.7 16.8 2.6 26.7 34.5 10.1 24.5 11.9 8.8 6.9 8.9 25.8 14.9 23.5 2.5 18.4 16.2 13.9 4.0 3.2 16.1 7.7 7.2 1.9 15.1 19.7 16.5 3.5 1.4 34.0 12.3 6.8 9.4 26.8 44.0 53.1 9.4 13.7 6.6 9.6 10.8 16.3 31.3 13.4 6.3 13.0 11.9 9.7 23.6 14.5 PGM1 ENSG00000079739 "Phosphoglucomutase 1" P36871 1 63593411-63660245 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Congenital disorder of glycosylation, Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 1559.1;tongue: 788.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 238.4;Extravillous trophoblasts: 185.9;Hepatocytes: 214.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004666, HPA024190, HPA024637, HPA046329" Enhanced Supported Cytosol NA NA 21000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB004666: AB_425590, HPA024190: AB_1855266, HPA024637: AB_1855267, HPA046329: AB_2679625" "unprognostic (2.50e-1)" "unprognostic (2.26e-3)" "unprognostic (1.74e-2)" "unprognostic (5.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-2)" "unprognostic (1.86e-3)" "unprognostic (2.42e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.74e-5)" "unprognostic (7.07e-2)" "unprognostic (1.55e-2)" "unprognostic (6.58e-3)" "unprognostic (1.37e-1)" "unprognostic (2.46e-1)" "unprognostic (9.74e-3)" 113.7 70.8 31.6 20.7 34.7 21.5 57.4 34.3 38.4 33.9 53.1 58.9 60.8 22.9 19.2 49.3 17.0 30.3 178.9 31.4 34.0 52.2 279.8 42.6 14.7 44.7 34.1 51.0 112.2 65.3 31.8 26.9 32.7 46.6 49.9 22.6 41.8 49.7 1559.1 30.6 55.1 41.4 31.9 14.7 30.6 11.1 36.5 14.3 27.5 788.0 19.4 38.4 22.1 30.2 113.4 47.0 17.3 57.0 111.0 81.4 138.6 45.7 61.8 48.9 79.0 38.8 51.3 35.8 93.2 71.2 107.4 26.5 24.0 96.3 55.9 44.0 32.1 75.3 72.6 40.3 91.6 66.8 4.3 103.4 60.7 57.1 88.5 129.8 29.6 36.3 0.1 46.3 78.8 6.9 19.6 36.7 78.3 3.4 73.9 26.8 80.0 11.8 70.0 35.3 10.4 66.7 100.0 103.0 157.4 78.6 32.4 25.2 3.1 71.6 36.0 64.0 39.4 29.1 45.5 57.8 117.0 58.0 31.5 46.0 33.2 49.2 40.5 22.4 32.7 22.4 23.5 31.0 48.4 11.8 21.0 24.7 38.7 43.9 21.2 13.9 20.4 35.4 31.6 34.7 34.3 38.4 31.4 34.0 44.7 34.1 32.7 31.9 36.5 30.2 8.4 93.0 29.4 48.3 16.9 17.8 29.0 58.8 47.8 9.2 33.8 21.8 139.2 48.6 24.2 16.5 10.4 76.6 14.2 81.8 88.0 55.9 32.0 8.2 12.1 12.7 13.1 5.7 17.9 238.4 185.9 37.0 27.0 13.5 5.1 134.3 15.0 214.4 24.6 0.0 26.3 47.5 20.3 17.0 10.8 8.5 22.1 13.5 26.6 4.7 32.8 75.8 29.9 32.2 9.8 70.5 31.6 38.0 40.4 29.2 90.2 74.8 17.0 11.4 13.1 53.4 25.5 5.6 10.1 57.3 18.2 58.8 19.0 20.2 81.5 19.0 PHC2 "EDR2, HPH2" ENSG00000134686 "Polyhomeotic homolog 2" Q8IXK0 1 33323623-33431052 "Predicted intracellular proteins" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 93.4" "Lineage enriched" "Detected in all" 11 "granulocytes: 93.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047403 Supported Supported Nucleoplasm NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA047403: AB_10964220" "unprognostic (8.58e-3)" "unprognostic (2.10e-1)" "unprognostic (9.51e-2)" "unprognostic (3.69e-1)" "unprognostic (2.00e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.28e-6)" "unprognostic (1.04e-1)" "unprognostic (2.40e-1)" "unprognostic (7.91e-2)" "unprognostic (3.08e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (2.35e-4)" "unprognostic (2.16e-1)" "unprognostic (1.57e-1)" "unprognostic (3.65e-2)" "unprognostic (1.72e-1)" 114.4 87.1 57.1 52.1 66.9 50.6 103.8 62.5 64.3 87.1 73.5 104.3 26.0 86.3 27.9 50.7 86.2 49.2 113.1 56.0 63.6 141.7 124.9 135.0 31.3 79.7 67.7 66.9 54.8 33.4 70.5 46.2 68.9 79.9 27.9 51.1 68.8 44.6 260.0 68.2 64.2 60.2 64.5 118.9 92.7 62.2 67.1 40.4 81.7 74.7 23.9 97.2 63.5 72.5 53.0 34.0 145.3 56.0 149.3 169.9 43.2 51.4 111.1 70.0 76.5 21.5 115.2 47.2 42.4 81.3 56.7 27.4 29.2 88.0 67.2 22.9 26.6 31.5 15.7 54.9 229.2 38.8 29.1 279.3 53.4 126.3 99.0 133.2 93.9 44.9 28.3 35.1 185.1 21.8 84.8 39.7 33.1 89.4 97.8 95.0 60.4 26.3 128.4 39.5 88.3 81.0 40.2 39.9 204.7 60.7 19.9 49.5 93.8 69.5 35.0 59.9 98.1 24.3 18.0 35.6 165.5 40.7 195.3 10.5 6.6 3.4 2.0 6.7 1.6 1.4 2.2 1.8 3.4 1.2 2.6 1.4 93.4 2.1 8.3 3.9 1.6 2.2 57.1 66.9 62.5 64.3 56.0 63.6 79.7 67.7 68.9 64.5 67.1 72.5 89.3 16.0 13.9 24.2 5.6 14.1 28.9 16.2 4.6 75.9 24.1 30.9 31.8 25.8 13.2 35.0 68.8 11.3 17.4 19.5 17.6 34.4 58.2 18.7 40.2 43.0 37.7 17.4 60.7 44.4 9.2 32.9 14.8 28.5 6.3 39.4 47.8 55.6 21.4 62.2 82.0 21.9 18.3 75.7 14.1 72.9 29.2 55.3 21.4 61.8 18.4 58.5 8.2 91.0 117.2 85.8 11.0 29.7 2.5 23.8 11.2 31.7 14.8 78.5 13.1 24.2 48.7 14.2 8.6 7.9 10.9 11.5 11.4 30.0 20.0 30.9 PHGDH "PDG, PGDH, SERA" ENSG00000092621 "Phosphoglycerate dehydrogenase" O43175 1 119648411-119744218 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 135.0;Exocrine glandular cells: 136.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 25.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 975.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003681, HPA021241, HPA024031, CAB068216" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" No No 1100000 "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "CAB003681: AB_425928, CAB068216: AB_2665666, HPA021241: AB_1855299, HPA024031: AB_1855300" "unprognostic (2.30e-1)" "unprognostic (2.16e-1)" "unprognostic (1.80e-2)" "prognostic unfavorable (1.48e-4)" "prognostic favorable (1.62e-4)" "unprognostic (9.80e-2)" "unprognostic (1.56e-2)" "unprognostic (1.40e-1)" "unprognostic (5.24e-2)" "unprognostic (4.45e-3)" "unprognostic (8.80e-3)" "unprognostic (5.00e-2)" "unprognostic (2.37e-2)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (1.78e-3)" 51.4 3.0 113.6 9.4 125.3 11.4 30.1 130.7 125.9 46.1 89.1 27.2 7.6 25.4 79.6 56.6 49.3 7.6 22.4 108.8 128.8 40.9 126.0 18.0 14.9 121.8 113.9 46.1 171.1 103.9 23.7 13.2 122.4 52.6 7.0 7.5 156.2 33.5 2.6 92.5 13.3 15.0 117.0 6.5 41.7 40.3 115.8 34.0 29.5 4.3 13.3 35.8 62.9 153.6 156.8 35.2 148.0 444.6 64.9 82.8 286.1 101.0 209.3 132.9 257.6 195.7 28.6 0.1 58.1 270.5 16.6 205.6 216.8 224.6 83.9 1.1 162.1 29.1 151.3 153.3 135.7 214.3 1.7 147.6 338.6 146.8 142.2 83.0 100.1 519.7 71.4 443.9 66.8 380.9 222.8 90.1 440.0 93.3 274.6 228.0 181.1 24.8 9.6 120.4 160.8 146.0 65.9 63.9 975.9 103.9 164.8 505.7 0.9 38.3 172.1 207.3 134.8 294.0 79.9 246.1 456.9 328.2 302.7 5.3 1.1 0.2 4.7 0.3 0.2 11.1 2.4 8.2 5.3 4.0 13.0 25.2 2.2 1.8 0.3 2.6 4.5 6.3 113.6 125.3 130.7 125.9 108.8 128.8 121.8 113.9 122.4 117.0 115.8 153.6 5.3 3.2 12.6 31.6 10.0 51.9 118.1 24.2 42.7 0.7 29.7 38.0 2.1 128.7 12.5 20.2 2.1 49.9 2.2 1.6 135.0 60.2 51.2 15.6 3.8 6.9 1.8 5.5 0.3 136.1 54.0 58.7 8.6 12.2 5.7 30.9 3.6 96.1 9.2 0.0 0.6 3.6 18.3 2.2 4.3 116.9 67.7 6.5 56.9 2.8 11.0 82.4 0.0 14.1 32.3 35.6 2.0 127.9 27.4 62.1 0.2 118.4 24.7 3.4 13.1 11.2 48.8 20.0 19.4 57.5 77.1 25.3 5.9 71.4 3.2 56.8 PI15 P25TI ENSG00000137558 "Peptidase inhibitor 15" O43692 8 74824534-74855029 "Predicted secreted proteins" "Developmental protein, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.4;prostate: 31.0;smooth muscle: 49.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 36.8;Breast glandular cells: 73.2;Breast myoepithelial cells: 13.6;Prostatic glandular cells: 19.3;Smooth muscle cells: 36.2;Urothelial cells: 15.7" "Group enriched" "Detected in many" 7 "breast cancer: 11.1;melanoma: 8.6;prostate cancer: 18.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 23.3;SH-SY5Y: 21.3;SK-MEL-30: 30.0;U-266/70: 7.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 6.3" "HPA006593, HPA030057" Uncertain Approved Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" Vesicles Cytosol "HPA006593: AB_1078568, HPA030057: AB_10602143" "unprognostic (2.77e-1)" "unprognostic (1.57e-2)" "unprognostic (3.41e-1)" "unprognostic (1.88e-2)" "unprognostic (3.22e-1)" "unprognostic (3.24e-1)" "unprognostic (2.94e-2)" "unprognostic (2.33e-3)" "unprognostic (1.87e-1)" "unprognostic (2.25e-1)" "unprognostic (3.65e-2)" "unprognostic (1.85e-2)" "unprognostic (8.63e-14)" "unprognostic (2.54e-3)" "unprognostic (1.34e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" 5.8 1.1 0.6 54.4 0.8 0.0 22.1 0.1 1.6 11.0 0.0 7.8 0.2 19.8 2.1 2.5 20.9 1.5 1.8 0.9 0.9 0.9 0.2 2.2 0.6 0.7 0.8 6.3 0.3 0.0 0.5 0.3 0.4 31.0 4.6 0.6 2.0 6.8 0.4 0.4 4.6 49.9 1.1 1.3 0.7 0.5 2.4 0.4 0.6 0.2 0.2 8.3 6.5 0.6 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.1 21.3 0.0 0.1 30.0 0.4 0.5 0.5 0.0 0.0 0.5 0.0 0.1 7.9 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.1 1.6 0.9 0.9 0.7 0.8 0.4 1.1 2.4 0.6 0.2 0.0 0.0 2.3 0.1 0.1 36.8 0.0 0.6 0.2 73.2 13.6 0.5 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 1.6 0.2 9.1 2.5 0.0 0.0 4.3 0.0 0.4 3.9 0.5 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.6 1.9 0.9 0.2 3.6 1.0 0.0 0.0 0.0 0.5 2.0 0.0 0.0 0.0 0.1 19.3 0.0 0.1 0.0 0.5 0.0 1.7 36.2 0.0 0.0 0.4 0.0 0.1 0.4 0.0 0.0 15.7 PIGP "DCRC, DSCR5, DSRC" ENSG00000185808 "Phosphatidylinositol glycan anchor biosynthesis class P" P57054 21 37062846-37073170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 350.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026921 Uncertain Approved Vesicles Yes No "Cluster 30: Non-specific - Translation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA026921: AB_1847874" "unprognostic (4.47e-3)" "unprognostic (9.45e-2)" "unprognostic (3.03e-1)" "unprognostic (2.40e-1)" "unprognostic (2.85e-2)" "unprognostic (1.92e-2)" "unprognostic (1.92e-2)" "unprognostic (5.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.22e-2)" "unprognostic (4.21e-3)" "unprognostic (1.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.93e-1)" "unprognostic (5.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.55e-2)" 33.9 41.3 18.7 12.5 20.2 9.1 35.4 22.4 24.7 22.9 24.8 24.2 19.0 18.3 107.2 16.8 25.7 22.5 40.1 18.1 22.8 35.9 54.7 21.6 16.6 22.8 21.6 27.9 41.4 51.9 38.0 20.9 22.6 33.7 27.4 28.6 32.2 26.7 44.0 12.4 15.5 17.1 22.1 14.9 22.8 36.5 20.0 22.0 36.3 42.8 19.7 26.2 13.2 25.4 25.9 11.5 23.7 14.8 41.5 28.6 16.9 21.9 38.7 18.6 21.1 15.4 53.7 37.1 45.7 32.0 81.4 19.4 22.7 25.5 18.5 37.4 36.1 86.2 13.8 21.3 26.3 26.9 16.6 26.5 47.2 33.4 43.0 42.2 35.1 80.5 50.7 61.8 38.5 16.5 32.9 25.5 19.6 76.8 27.9 31.0 12.1 37.0 48.2 13.3 49.2 29.8 61.4 43.0 81.8 33.6 35.2 53.2 18.3 12.9 6.6 14.8 19.3 81.1 96.5 42.0 38.1 30.5 43.4 0.4 13.5 3.7 19.6 20.3 24.8 34.2 25.1 21.6 20.9 28.1 33.3 29.0 1.9 16.8 22.6 30.9 20.6 15.6 18.7 20.2 22.4 24.7 18.1 22.8 22.8 21.6 22.6 22.1 20.0 25.4 37.4 28.9 41.8 9.8 37.0 33.0 58.9 88.9 35.3 21.2 74.1 86.4 82.4 42.9 65.1 44.1 10.4 60.7 29.4 21.6 90.1 61.8 79.3 67.0 35.9 31.3 44.9 25.7 6.9 71.3 52.4 48.9 30.1 49.3 15.9 32.2 35.3 79.8 66.7 16.8 8.7 63.9 65.1 57.6 39.9 75.6 69.0 44.1 37.4 2.8 50.2 37.0 23.7 7.5 18.2 57.7 50.3 35.0 54.3 45.6 52.3 97.1 86.9 33.6 65.7 32.7 44.6 350.8 177.5 44.2 26.3 52.3 31.7 62.6 53.1 63.7 PIGY MGC14156 ENSG00000255072 "Phosphatidylinositol glycan anchor biosynthesis class Y" Q3MUY2 4 88520998-88523776 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059018 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "HPA059018: AB_2683884" 35.7 39.6 35.1 23.1 37.0 44.5 48.2 38.7 43.4 32.1 33.8 30.7 30.7 34.0 45.6 28.4 33.8 22.5 32.3 34.0 37.3 41.2 52.0 26.3 27.8 36.7 35.6 34.3 41.3 41.9 3.3 28.5 36.5 32.3 31.2 22.9 43.1 33.9 48.6 27.1 28.3 36.2 39.2 26.1 24.6 22.4 36.2 27.3 32.0 42.3 29.4 28.7 3.7 39.3 60.1 19.8 39.1 46.4 76.7 78.3 26.2 43.2 60.6 53.1 44.6 15.5 46.3 0.2 47.3 61.7 36.4 25.2 35.6 54.4 66.6 73.4 61.8 66.2 24.8 59.9 58.0 110.7 40.9 54.4 80.8 34.5 69.5 50.4 88.5 20.4 75.9 64.9 77.8 45.5 68.5 67.6 32.7 70.5 37.5 68.0 36.3 69.8 44.4 33.4 46.7 45.7 54.9 49.4 119.9 38.4 23.0 54.8 60.6 56.1 51.9 55.3 40.6 45.6 40.1 7.5 49.3 55.7 63.1 82.4 92.1 79.0 90.4 94.9 102.2 98.9 103.2 98.3 111.0 80.5 105.4 101.6 18.1 108.9 95.3 68.3 116.8 186.1 35.1 37.0 38.7 43.4 34.0 37.3 36.7 35.6 36.5 39.2 36.2 39.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PIP4P2 "DKFZp762O076, TMEM55A" ENSG00000155099 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2" Q8N4L2 8 90993802-91040872 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 26.2;Cytotrophoblasts: 32.6;Distal tubular cells: 49.0;Extravillous trophoblasts: 31.1;Hofbauer cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 76.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 76.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014591 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "HPA014591: AB_1858124" "unprognostic (6.09e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.54e-4)" "prognostic unfavorable (3.76e-5)" "unprognostic (3.76e-2)" "unprognostic (1.08e-1)" "unprognostic (7.58e-2)" "unprognostic (4.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.59e-1)" "unprognostic (9.05e-2)" "unprognostic (7.99e-2)" 11.9 13.9 13.2 6.6 15.7 30.0 7.4 16.5 20.1 9.2 20.2 14.6 2.8 10.5 4.2 5.9 7.2 11.0 20.7 13.3 20.4 10.0 3.8 5.5 6.9 16.5 16.4 10.6 3.3 10.9 7.9 8.8 18.2 8.7 4.8 11.0 7.3 12.2 13.5 6.5 5.3 13.5 16.4 8.3 6.5 6.9 17.5 9.5 6.6 14.8 5.4 9.9 6.6 21.0 4.8 2.9 16.8 10.2 27.2 30.6 3.5 19.3 24.2 10.2 15.1 1.9 8.1 9.4 2.6 19.9 10.3 1.1 4.2 7.0 13.6 8.1 7.3 13.9 2.9 1.5 23.6 3.3 12.2 17.2 4.4 12.8 9.6 27.4 9.8 2.7 7.4 31.0 35.6 3.3 10.4 9.5 8.6 0.0 9.8 3.9 6.9 11.2 14.9 3.0 2.0 9.7 1.5 6.6 28.4 11.4 0.2 6.3 15.1 18.5 7.1 11.2 9.0 12.0 7.0 6.0 31.6 6.4 25.2 0.9 11.6 10.8 1.3 5.9 2.3 2.7 3.1 1.7 10.8 1.9 4.8 1.9 76.9 2.4 2.2 6.0 2.8 6.1 13.2 15.7 16.5 20.1 13.3 20.4 16.5 16.4 18.2 16.4 17.5 21.0 26.2 0.0 2.8 0.0 4.4 0.0 0.0 0.0 0.0 0.0 7.5 11.2 0.0 0.0 3.1 9.2 0.0 32.6 7.7 0.0 49.0 18.0 0.0 0.8 11.7 5.2 0.0 0.0 0.0 8.9 31.1 18.7 0.0 1.0 8.8 4.1 0.0 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 3.6 0.0 0.0 0.0 0.0 15.8 0.0 0.0 2.1 0.0 0.0 13.1 1.5 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 10.9 3.7 14.3 0.0 0.0 PLA1A ps-PLA1 ENSG00000144837 "Phospholipase A1 member A" Q53H76 3 119597875-119629811 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 138.4;parathyroid gland: 65.8;seminal vesicle: 67.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 14.7;Endothelial cells: 14.3;Hepatocytes: 26.0;Langerhans cells: 15.6;Peritubular cells: 14.3" "Group enriched" "Detected in many" 5 "liver cancer: 14.8;melanoma: 55.4;prostate cancer: 24.2;renal cancer: 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "SK-MEL-30: 25.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059740 Approved "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" "Secreted in other tissues" NA NA 420000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytoplasmic bodies" Nucleoplasm "HPA059740: AB_2684118" "unprognostic (1.35e-1)" "prognostic favorable (2.81e-7)" "unprognostic (2.24e-2)" "unprognostic (3.46e-2)" "unprognostic (3.18e-2)" "unprognostic (1.94e-2)" "unprognostic (1.11e-2)" "unprognostic (2.43e-1)" "unprognostic (3.87e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" "unprognostic (9.09e-2)" "unprognostic (1.55e-3)" "unprognostic (9.53e-3)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" "unprognostic (2.67e-1)" 4.9 0.7 12.1 3.5 11.3 0.3 3.4 11.6 16.3 4.7 26.8 2.7 1.1 4.7 138.4 1.5 5.7 2.8 4.9 12.5 12.0 7.7 39.6 21.2 15.6 13.2 12.3 1.1 3.7 65.8 1.7 9.8 13.2 9.1 2.5 1.0 3.5 67.2 16.2 0.8 3.5 8.8 13.4 1.0 4.4 3.7 14.7 1.6 6.9 3.1 8.7 3.9 1.9 12.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.8 0.3 0.5 0.1 0.0 0.2 0.0 0.0 25.0 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 12.1 11.3 11.6 16.3 12.5 12.0 13.2 12.3 13.2 13.4 14.7 12.4 6.5 0.0 1.7 0.0 0.0 0.6 0.5 0.4 0.6 0.0 0.1 0.1 2.8 2.8 1.0 14.7 0.0 0.2 0.1 0.0 1.9 4.7 6.6 0.1 0.1 14.3 1.8 0.0 0.2 2.2 0.0 1.6 0.0 0.9 1.3 0.7 7.9 26.0 1.6 0.0 0.1 0.1 0.0 1.0 15.6 3.2 0.3 5.4 1.8 4.7 4.2 0.0 0.0 0.0 0.0 1.3 0.6 14.3 0.0 0.5 0.0 5.1 7.5 0.1 0.0 0.9 5.9 0.0 0.2 0.0 0.6 1.9 0.1 0.0 0.1 0.2 PLEKHA4 PEPP1 ENSG00000105559 "Pleckstrin homology domain containing A4" Q9H4M7 19 48837097-48868617 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 53.4;Smooth muscle cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 63.4;BJ hTERT+ SV40 Large T+ RasG12V: 49.5;SK-MEL-30: 77.0" "Low region specificity" "Detected in some" "Region enriched" "Detected in many" 6 "spinal cord: 45.0" "HPA042978, HPA048473" Uncertain Approved "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "Cytokinetic bridge, Centriolar satellite" "HPA042978: AB_2678249, HPA048473: AB_2680409" "prognostic favorable (1.97e-4)" "unprognostic (4.39e-1)" "unprognostic (8.16e-2)" "unprognostic (2.85e-2)" "unprognostic (3.98e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (8.68e-4)" "unprognostic (5.09e-2)" "unprognostic (1.01e-2)" "unprognostic (1.17e-1)" "unprognostic (1.18e-2)" "unprognostic (2.95e-1)" "unprognostic (3.84e-2)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-3)" "unprognostic (6.38e-2)" 34.0 24.6 8.8 12.1 8.8 0.7 31.7 8.0 9.5 28.7 10.9 43.0 5.6 34.6 5.0 14.3 30.5 11.1 41.4 8.7 10.6 32.4 32.8 25.7 5.8 16.9 14.7 47.5 13.2 9.5 29.9 5.6 10.4 28.3 3.9 2.5 15.1 8.4 19.3 17.2 16.0 10.7 10.8 16.2 21.1 11.0 12.4 5.5 31.0 13.1 3.3 34.4 21.7 10.3 9.0 0.5 9.9 63.4 14.2 41.7 8.0 7.0 24.7 26.8 49.5 5.9 2.5 0.4 11.8 9.8 10.4 2.7 3.5 3.6 4.2 0.0 3.4 2.3 1.7 6.6 11.0 0.0 14.2 21.5 2.2 15.6 1.0 11.1 8.0 11.2 9.5 5.3 7.4 5.4 3.2 0.5 1.5 6.0 0.8 0.3 31.5 0.6 8.3 0.1 0.0 11.0 3.0 2.6 77.0 2.5 3.9 3.0 1.3 8.5 6.8 11.2 1.8 28.3 25.4 5.3 10.2 0.7 23.0 0.0 0.3 0.9 1.8 0.3 1.3 1.7 1.7 1.1 0.1 3.9 2.8 2.6 0.1 0.8 0.3 1.2 0.6 0.9 8.8 8.8 8.0 9.5 8.7 10.6 16.9 14.7 10.4 10.8 12.4 10.3 6.4 0.0 18.7 2.3 1.4 9.6 31.3 17.6 12.0 0.7 11.4 18.3 37.1 17.2 27.2 7.3 0.0 3.3 2.9 3.2 1.9 23.3 0.8 11.6 34.1 7.0 1.2 3.2 0.4 5.1 6.8 41.7 7.7 11.6 0.0 18.8 6.4 13.3 2.9 0.0 0.5 2.5 4.1 0.8 9.2 2.0 41.3 1.9 12.4 1.9 1.3 9.9 2.1 0.5 0.2 6.9 0.5 53.4 0.7 29.8 0.7 14.6 20.5 1.0 6.6 33.0 48.4 4.0 3.7 5.7 9.8 2.9 2.4 16.0 3.3 21.4 PLEKHH1 KIAA1200 ENSG00000054690 "Pleckstrin homology, MyTH4 and FERM domain containing H1" Q9ULM0 14 67533290-67589612 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 158.0" "Cell type enriched" "Detected in many" 8 "Oligodendrocytes: 607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 10.2;BEWO: 9.7;RT4: 10.2;SK-MEL-30: 12.0;T-47d: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047707, HPA051964" Uncertain Approved Centrosome NA NA "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Centrosome "HPA047707: AB_2680126, HPA051964: AB_2681675" "unprognostic (2.47e-2)" "unprognostic (9.57e-2)" "unprognostic (3.94e-2)" "prognostic favorable (8.03e-5)" "unprognostic (4.74e-1)" "unprognostic (9.15e-3)" "unprognostic (8.43e-5)" "unprognostic (1.54e-2)" "unprognostic (2.28e-1)" "unprognostic (4.14e-2)" "unprognostic (3.72e-2)" "unprognostic (1.85e-1)" "prognostic favorable (4.03e-7)" "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "prognostic favorable (2.26e-4)" 0.9 4.0 20.9 1.3 72.6 0.0 2.5 44.6 51.6 2.9 0.0 6.7 11.7 1.4 8.3 1.2 3.4 2.1 0.7 24.9 31.9 2.1 0.4 0.7 0.1 78.9 59.7 0.2 7.7 9.5 4.3 1.1 71.2 10.3 6.7 7.3 22.8 2.3 0.9 4.3 9.3 0.8 36.8 0.9 6.3 1.8 59.7 1.1 38.9 0.4 0.3 1.4 0.9 158.0 5.3 1.2 2.0 10.2 0.2 0.0 9.7 0.0 0.0 0.1 0.1 3.2 1.6 0.0 1.6 0.0 0.9 2.3 3.6 0.9 0.1 0.3 3.5 0.0 1.8 2.1 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 1.3 4.0 0.0 0.0 7.6 0.0 0.2 3.0 6.0 0.6 0.1 0.3 1.5 1.1 10.2 2.7 2.5 0.9 1.9 12.0 4.7 9.7 2.1 0.0 0.8 3.6 1.0 0.6 0.0 0.0 0.0 0.5 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.9 72.6 44.6 51.6 24.9 31.9 78.9 59.7 71.2 36.8 59.7 158.0 0.1 3.2 6.4 19.9 0.7 0.1 0.7 3.1 1.2 16.7 5.8 6.0 3.6 2.8 3.4 9.2 39.6 3.0 1.4 21.2 3.9 2.2 0.6 19.1 2.0 0.7 7.3 0.0 13.4 4.0 0.3 0.6 29.0 18.0 0.0 67.7 0.0 0.2 0.8 3.3 21.9 16.9 0.0 0.6 0.3 0.7 0.3 1.5 3.6 12.2 0.0 4.6 0.0 34.2 607.7 2.9 7.7 0.4 0.0 4.1 12.8 1.7 3.9 36.6 0.0 1.5 1.0 0.7 1.6 2.3 2.3 10.7 0.3 2.0 16.4 1.2 PLEKHM2 KIAA0842 ENSG00000116786 "Pleckstrin homology and RUN domain containing M2" Q8IWE5 1 15684320-15734769 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032304 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA032304: AB_10670964" "unprognostic (3.07e-2)" "unprognostic (1.89e-1)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.36e-8)" "unprognostic (4.01e-2)" "unprognostic (1.60e-1)" "unprognostic (1.10e-3)" "unprognostic (1.03e-2)" "unprognostic (2.59e-1)" "unprognostic (6.73e-3)" "unprognostic (3.30e-1)" "unprognostic (5.50e-1)" "unprognostic (6.49e-2)" "unprognostic (1.89e-2)" 40.2 37.7 72.3 23.0 76.1 66.2 32.3 63.5 121.9 33.4 44.6 32.4 16.3 32.0 7.6 40.5 27.0 22.0 61.3 78.4 57.2 26.3 20.6 46.9 26.4 65.3 63.3 33.3 27.7 24.6 26.8 22.8 63.8 29.5 9.0 8.2 27.2 15.2 136.0 47.6 27.8 17.1 60.0 42.9 28.3 35.6 70.6 18.9 28.2 62.9 17.4 32.3 34.6 85.9 43.1 25.5 24.4 42.7 56.8 45.3 26.5 36.3 58.9 45.1 41.4 35.0 37.7 23.9 37.8 55.8 45.6 25.2 19.0 40.9 17.2 46.4 33.2 29.5 43.3 27.3 59.9 25.0 32.5 52.2 45.2 47.0 53.2 51.9 34.2 39.6 35.8 63.0 23.3 33.5 28.5 25.9 18.6 14.4 21.1 38.7 21.3 32.3 22.1 18.7 25.3 34.5 40.7 24.1 99.1 16.6 16.3 37.8 38.8 62.3 29.0 62.7 27.5 31.9 23.2 29.7 53.7 39.7 38.7 0.3 2.8 1.8 1.8 2.8 1.4 2.1 1.2 0.7 2.6 2.4 1.5 1.2 3.0 1.1 3.3 2.1 0.8 1.5 72.3 76.1 63.5 121.9 78.4 57.2 65.3 63.3 63.8 60.0 70.6 85.9 25.6 16.0 16.0 28.7 15.5 24.9 11.7 8.8 3.4 28.4 14.2 14.2 26.6 8.6 7.8 16.5 22.9 7.8 16.8 16.6 1.9 13.1 31.6 15.1 26.1 18.9 11.3 2.5 27.2 17.8 8.9 23.3 14.3 25.7 18.4 25.5 26.7 11.6 37.2 28.6 25.8 15.4 6.1 38.9 20.9 24.5 20.5 36.9 8.8 23.4 14.5 28.4 3.1 16.6 17.6 23.4 14.7 18.0 8.7 19.2 10.5 6.8 8.9 21.1 0.0 27.4 18.7 18.4 6.0 15.9 36.1 24.6 11.8 26.1 12.2 23.9 PLP1 "GPM6C, PLP, SPG2" ENSG00000123560 "Proteolipid protein 1" P60201 X 103773718-103792619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 7004.9" "Cell type enriched" "Detected in some" 12 "Oligodendrocytes: 4822.5" "Group enriched" "Detected in many" 22 "glioma: 160.5;melanoma: 75.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SK-MEL-30: 241.0;WM-115: 139.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004128 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA004128: AB_1079635" "unprognostic (5.72e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-2)" "unprognostic (4.09e-3)" "unprognostic (1.32e-1)" "unprognostic (3.95e-2)" "unprognostic (2.57e-2)" "unprognostic (1.02e-1)" "unprognostic (5.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-5)" "unprognostic (4.91e-2)" "unprognostic (1.86e-1)" "unprognostic (3.46e-2)" "unprognostic (1.16e-2)" 7.3 15.7 2252.5 4.2 4296.1 0.1 5.4 4251.8 3472.7 17.8 1056.0 73.9 6.3 6.8 6.7 9.9 7.3 9.6 30.1 2314.1 2859.4 2.9 2.0 1.2 0.4 5976.3 3571.3 5.7 2.5 83.1 6.4 0.0 5342.5 21.1 14.9 7.5 6.7 30.0 2.4 24.4 22.4 22.7 3919.9 0.5 15.4 33.5 3592.5 3.8 3.4 6.8 0.4 12.9 21.8 7004.9 0.2 0.0 20.7 0.1 0.0 0.3 0.0 0.0 0.4 0.0 0.8 1.9 0.0 0.0 0.2 0.7 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 4.0 0.0 0.2 0.0 0.9 0.0 0.1 0.0 2.8 0.0 0.0 0.1 0.0 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 241.0 6.3 0.1 0.2 0.0 0.1 0.4 0.1 0.2 0.0 0.3 0.2 4.0 0.0 139.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2252.5 4296.1 4251.8 3472.7 2314.1 2859.4 5976.3 3571.3 5342.5 3919.9 3592.5 7004.9 0.5 0.0 0.0 23.8 0.1 15.9 0.3 0.0 6.2 1.7 0.2 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.0 9.7 0.0 0.0 13.3 0.0 0.0 0.0 188.3 3.3 0.0 0.1 0.0 11.2 0.0 0.0 0.0 5.8 3.1 7.5 0.8 396.6 17.8 0.0 30.7 0.0 31.2 4822.5 0.0 0.0 3.0 0.0 0.8 0.0 0.0 0.0 1.1 0.0 3.1 2.4 0.6 0.3 0.8 2.6 0.0 0.2 5.6 0.0 0.1 PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 319.8;BJ hTERT+ SV40 Large T+ RasG12V: 418.6;HHSteC: 292.9;SK-MEL-30: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB070421: AB_11153452, HPA068923: AB_2686059" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (5.34e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (3.35e-1)" "unprognostic (5.22e-2)" "unprognostic (7.73e-3)" "unprognostic (9.19e-3)" "unprognostic (6.93e-3)" "unprognostic (3.07e-3)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.26e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" 60.6 23.0 11.4 86.7 12.5 64.4 45.9 12.7 17.6 25.9 11.9 65.0 39.8 28.2 31.0 47.9 40.0 66.1 24.3 12.1 13.5 71.9 49.2 49.3 40.6 17.4 14.2 34.9 38.3 16.8 15.4 56.3 15.3 23.7 59.5 9.8 49.1 49.6 10.8 13.6 45.4 41.9 16.2 64.5 44.0 17.1 14.7 30.0 27.8 17.6 39.4 68.1 29.5 14.0 106.2 41.5 26.4 12.1 40.9 65.0 40.5 32.6 88.4 319.8 418.6 34.0 88.1 8.4 75.6 20.6 245.9 86.2 21.2 32.7 56.6 32.9 21.6 66.1 12.5 25.2 292.9 40.3 35.4 106.3 53.3 36.6 182.3 52.6 49.4 19.1 44.7 104.0 66.9 41.0 30.6 16.1 25.8 71.6 37.6 27.4 28.1 2.9 95.9 29.6 16.3 0.0 42.6 20.9 569.9 35.8 20.7 46.8 30.6 26.9 22.7 59.1 55.8 79.2 15.6 0.4 27.0 29.0 23.3 41.1 157.6 44.3 20.8 159.6 30.0 25.2 13.5 18.5 105.8 19.7 9.3 13.9 100.0 57.8 94.8 28.5 8.3 79.3 11.4 12.5 12.7 17.6 12.1 13.5 17.4 14.2 15.3 16.2 14.7 14.0 191.4 35.3 43.0 12.7 28.2 37.0 106.5 92.1 26.2 0.7 36.0 22.6 7.3 124.4 110.4 95.6 0.0 53.7 25.4 134.2 74.3 291.6 2.0 56.1 24.5 135.2 33.1 18.3 7.1 217.4 114.1 74.8 47.9 58.2 28.4 60.5 100.6 29.7 139.9 0.0 9.0 71.5 79.3 86.2 162.9 6.8 114.9 185.5 48.0 35.6 72.3 64.3 32.0 7.1 0.3 157.6 110.3 45.9 18.2 79.6 40.7 75.0 133.5 1.6 39.5 63.4 59.2 1.5 2.4 21.8 28.6 44.5 25.9 42.6 69.4 211.9 PMEL "D12S53E, gp100, Pmel17, SI, SIL, SILV" ENSG00000185664 "Premelanosome protein" P40967 12 55954105-55973317 "Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "cervix: 80.5;endometrium 1: 32.2;skin 1: 115.2" "Cell type enriched" "Detected in many" 32 "Melanocytes: 1472.7" "Cancer enriched" "Detected in many" 500 "melanoma: 2481.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 68 "SK-MEL-30: 8590.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031649 Enhanced Supported "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA 11000000 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "Golgi apparatus" "HPA031649: AB_2673976" "unprognostic (4.63e-1)" "unprognostic (8.93e-2)" "unprognostic (1.53e-1)" "unprognostic (1.60e-1)" "unprognostic (5.90e-2)" "unprognostic (6.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.46e-3)" "unprognostic (6.44e-2)" "unprognostic (1.21e-1)" "unprognostic (5.12e-2)" "unprognostic (3.98e-1)" "prognostic favorable (3.70e-4)" "unprognostic (2.86e-2)" "unprognostic (1.54e-1)" "unprognostic (7.60e-2)" "unprognostic (1.04e-1)" 3.3 0.8 0.2 0.8 0.2 1.8 8.3 0.7 0.5 80.5 0.3 1.3 1.6 32.2 1.5 0.7 1.2 1.6 0.6 0.3 0.0 2.1 5.0 0.9 5.6 0.0 0.4 4.3 2.3 1.7 0.7 2.8 0.1 0.9 1.2 0.4 3.5 0.8 0.3 115.2 2.1 3.5 0.0 0.5 1.1 4.8 0.0 0.7 1.1 0.2 2.2 1.3 4.0 0.3 14.8 1.1 5.6 0.2 83.6 0.6 126.2 0.9 0.8 1.9 2.0 12.8 6.0 2.6 6.1 0.8 0.3 2.5 0.6 1.0 1.6 3.0 2.1 2.4 2.5 0.7 0.3 1.0 1.4 0.5 1.0 1.2 0.6 1.3 1.0 1.1 0.5 1.8 0.5 2.7 0.4 1.0 17.1 2.8 0.3 1.6 3.5 1.5 1.4 2.7 0.5 2.6 0.3 2.5 8590.9 4.6 4.4 8.8 1.4 0.9 6.5 0.7 7.9 2.1 10.4 3.2 1.0 2.7 0.3 0.0 0.3 0.1 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.4 0.0 0.1 0.2 0.2 0.7 0.5 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.8 0.0 0.5 0.0 0.1 45.9 0.8 1.1 2.8 0.0 1.0 0.9 0.4 1.5 2.2 0.0 0.0 12.1 0.0 1.5 0.0 2.1 8.0 0.7 0.2 1.2 0.0 0.8 0.1 2.3 12.4 1.6 1.1 0.5 0.0 11.1 0.0 2.9 1.7 0.0 0.1 1.6 0.0 0.3 14.6 5.3 12.2 0.6 1472.7 1.0 0.6 0.2 0.0 0.0 0.1 1.0 0.6 0.7 1.2 0.5 2.4 2.8 1.0 0.0 0.0 0.2 1.7 3.9 2.6 1.0 10.2 24.9 0.4 1.3 1.6 0.4 POU3F1 "OCT6, OTF6, SCIP" ENSG00000185668 "POU class 3 homeobox 1" Q03052 1 38043829-38046793 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 10.3;skin 1: 32.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 27.3;Breast myoepithelial cells: 39.1;Cone photoreceptor cells: 22.9;Suprabasal keratinocytes: 55.8" "Group enriched" "Detected in many" 4 "cervical cancer: 1.8;head and neck cancer: 4.4;melanoma: 4.8;testis cancer: 1.3;urothelial cancer: 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 24.1;HDLM-2: 23.9;NTERA-2: 7.5;SCLC-21H: 5.7;SK-MEL-30: 28.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055980, HPA073824" Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA055980: AB_2682995, HPA073824: AB_2686635" "unprognostic (9.99e-2)" "unprognostic (1.63e-1)" "unprognostic (1.69e-1)" "unprognostic (1.43e-2)" "unprognostic (7.46e-3)" "unprognostic (1.96e-2)" "unprognostic (1.33e-2)" "unprognostic (2.56e-1)" "unprognostic (1.11e-1)" "unprognostic (3.07e-2)" "unprognostic (4.40e-2)" "unprognostic (1.40e-1)" "unprognostic (4.61e-4)" "unprognostic (2.79e-2)" "unprognostic (1.97e-1)" "unprognostic (3.61e-2)" "unprognostic (2.67e-3)" 0.2 1.5 2.3 0.2 7.0 0.0 0.3 0.9 10.3 0.2 0.1 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.1 9.7 1.9 0.0 0.0 0.0 1.0 1.4 2.6 0.1 0.1 0.2 0.0 0.0 1.3 0.2 0.0 0.3 0.3 0.1 0.9 32.6 0.0 0.0 0.6 0.1 0.1 0.8 2.0 0.3 0.0 0.5 1.0 0.8 0.3 2.5 0.0 0.0 24.1 0.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 23.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.0 1.4 5.7 0.0 0.1 0.0 28.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 7.0 0.9 10.3 9.7 1.9 1.4 2.6 1.3 0.6 2.0 2.5 12.2 0.0 0.0 2.3 8.3 27.3 2.9 1.4 20.5 7.8 9.9 39.1 5.2 0.0 0.2 0.0 22.9 0.2 13.4 13.8 0.0 0.0 0.2 0.5 2.3 1.9 1.8 2.7 6.4 0.0 0.1 5.2 7.1 1.4 0.0 0.5 0.0 0.0 0.3 1.7 1.1 11.0 0.0 0.0 1.3 0.0 0.3 4.3 7.2 1.0 0.0 14.0 0.0 0.5 0.2 0.0 0.1 0.0 2.7 0.7 0.3 0.1 0.0 21.1 0.0 8.5 7.2 0.2 4.1 20.2 55.8 0.1 5.2 8.3 5.7 3.2 PPFIA1 "LIP.1, LIPRIN" ENSG00000131626 "PTPRF interacting protein alpha 1" Q13136 11 70270690-70385312 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 190.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A-431: 261.2;SK-MEL-30: 156.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017032, HPA042271" Uncertain Supported "Focal adhesion sites,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Focal adhesion sites" "CAB017032: , HPA042271: AB_2677923" "unprognostic (1.89e-1)" "unprognostic (1.28e-2)" "unprognostic (6.27e-2)" "unprognostic (9.92e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.58e-4)" "unprognostic (7.20e-3)" "unprognostic (2.20e-1)" "unprognostic (3.02e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (8.26e-4)" "unprognostic (1.14e-1)" "prognostic favorable (3.76e-4)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (2.14e-2)" 26.6 14.6 17.5 16.1 18.2 20.6 17.6 16.0 19.2 13.1 22.1 18.2 14.0 17.9 13.7 16.4 12.1 22.1 14.5 15.6 15.8 16.4 15.0 19.8 15.7 25.9 21.0 15.1 15.9 18.0 13.2 24.1 20.6 12.4 15.8 14.9 13.4 14.0 31.6 18.0 16.2 17.4 17.6 15.3 13.5 26.3 20.1 15.7 23.3 26.8 14.0 17.0 12.1 25.1 261.2 30.4 31.8 22.5 33.1 20.3 34.9 30.0 24.4 40.8 26.0 66.8 22.8 25.8 39.6 27.3 39.4 38.3 30.7 28.3 35.9 15.5 21.5 19.7 34.3 24.7 33.4 26.2 22.1 24.9 46.8 53.1 44.6 31.4 27.9 21.3 33.1 19.9 37.3 30.8 19.3 17.7 19.7 59.5 34.3 20.6 80.2 22.2 20.6 32.9 31.9 21.5 45.2 59.1 156.6 36.0 37.5 31.2 30.0 38.0 29.8 54.3 32.4 24.7 15.8 37.3 28.2 20.1 43.0 0.0 1.6 1.1 0.8 1.2 1.2 1.5 1.2 1.1 1.3 1.0 0.9 0.6 5.0 0.4 3.5 1.7 1.2 0.6 17.5 18.2 16.0 19.2 15.6 15.8 25.9 21.0 20.6 17.6 20.1 25.1 33.0 25.6 53.5 114.6 19.3 27.4 26.4 14.2 30.1 39.1 32.8 24.1 27.2 20.0 25.1 18.4 31.3 44.2 14.2 39.3 11.7 21.8 190.4 28.7 44.4 31.4 26.9 24.8 57.8 20.3 13.7 33.3 25.5 45.4 8.8 94.3 20.7 25.2 25.2 33.7 52.8 19.8 16.2 35.5 28.8 97.7 27.7 40.4 21.4 38.4 28.8 71.8 17.5 47.7 56.4 36.2 24.7 25.6 23.6 36.7 19.2 22.7 27.1 45.8 19.7 45.4 30.0 60.7 61.9 36.1 33.1 74.3 22.2 42.2 25.1 37.2 PPP1CA "PP-1A, PP1A, PP1alpha, PPP1A" ENSG00000172531 "Protein phosphatase 1 catalytic subunit alpha" P62136 11 67398181-67421183 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004545, HPA046833" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB004545: AB_628177, HPA046833: AB_2679829" "unprognostic (1.03e-1)" "unprognostic (5.82e-3)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (3.15e-3)" "unprognostic (3.93e-2)" "unprognostic (2.07e-1)" "unprognostic (3.89e-2)" "unprognostic (5.05e-3)" "unprognostic (8.00e-2)" "unprognostic (1.66e-1)" "unprognostic (9.96e-2)" "unprognostic (7.69e-2)" "prognostic favorable (1.17e-4)" "unprognostic (7.60e-2)" 70.0 102.4 61.2 102.6 70.8 127.8 63.5 64.0 70.7 62.1 61.2 110.8 95.9 50.5 66.8 184.0 61.1 51.2 122.0 63.5 63.6 121.8 128.2 78.9 147.8 68.3 62.4 33.1 105.1 64.2 59.8 83.5 63.8 81.1 89.6 21.6 100.4 51.0 123.2 105.8 107.1 56.1 63.9 148.7 102.7 34.6 65.8 113.7 88.7 81.3 155.6 74.9 80.6 68.2 283.1 305.6 181.1 270.3 88.4 108.9 185.6 136.1 158.4 267.4 202.3 445.8 328.5 237.2 227.3 208.1 198.4 238.7 213.9 280.2 169.6 256.3 139.9 227.5 129.3 232.7 195.2 295.2 281.1 123.3 181.1 225.7 130.7 125.4 272.2 226.0 217.4 191.1 220.5 619.4 378.2 562.2 303.5 526.7 241.1 262.7 254.0 209.8 262.2 220.7 142.5 236.7 159.2 283.0 439.8 135.3 338.5 201.2 196.4 208.5 208.9 245.3 179.0 190.1 193.2 271.8 244.6 199.9 224.3 921.6 735.9 1234.1 779.2 962.9 604.3 733.4 679.9 792.5 705.3 779.6 412.6 584.2 853.8 688.8 1186.1 500.4 1098.7 2042.5 61.2 70.8 64.0 70.7 63.5 63.6 68.3 62.4 63.8 63.9 65.8 68.2 49.2 76.9 92.2 8.8 165.8 99.9 143.5 305.9 64.3 35.5 81.7 79.1 8.4 102.9 157.8 86.5 10.4 360.4 151.2 377.5 213.2 265.6 2.5 63.1 67.2 101.6 96.9 108.8 8.8 311.1 507.0 68.8 132.0 107.1 109.6 87.1 89.3 113.9 377.1 43.7 7.7 241.3 181.0 219.8 138.5 7.7 49.0 186.5 136.9 9.4 353.0 53.8 408.8 6.0 13.1 318.4 308.4 28.6 206.5 139.0 341.3 297.4 70.5 30.5 98.6 67.1 100.7 13.6 94.6 142.0 121.6 427.3 176.3 100.1 231.7 205.4 PPP6R3 "C11orf23, DKFZp781E17107, DKFZp781E2374, DKFZp781O2362, FLJ11058, FLJ43065, KIAA1558, MGC125711, MGC125712, PP6R3, SAP190, SAPL, SAPLa, SAPS3" ENSG00000110075 "Protein phosphatase 6 regulatory subunit 3" Q5H9R7 11 68460731-68615334 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 186.0;Oligodendrocytes: 213.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017183, HPA038467, HPA038468" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 6600 "Cluster 49: Eosinophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "CAB017183: , HPA038467: AB_2676029, HPA038468: AB_2676030" "unprognostic (9.46e-3)" "unprognostic (1.45e-1)" "unprognostic (4.62e-2)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (6.19e-2)" "unprognostic (1.97e-2)" "unprognostic (1.11e-1)" "unprognostic (1.71e-2)" "unprognostic (3.33e-2)" "unprognostic (1.02e-1)" "unprognostic (2.38e-2)" "unprognostic (2.20e-3)" "unprognostic (3.29e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (1.54e-2)" "unprognostic (6.43e-2)" 28.7 28.0 20.4 31.1 26.7 53.0 31.1 35.0 23.1 27.2 29.4 33.4 27.3 30.9 23.3 32.6 26.2 30.7 32.9 20.0 21.9 29.2 31.9 28.1 37.0 24.2 23.4 38.4 22.7 42.9 24.1 34.7 24.8 32.4 33.5 33.8 28.3 26.1 48.8 29.9 31.0 34.5 21.8 32.9 30.0 36.9 23.1 44.4 43.9 49.0 36.6 32.7 26.4 34.6 72.8 83.6 85.0 59.6 44.5 44.9 66.3 62.0 59.7 70.7 64.2 148.3 71.3 83.4 59.4 58.1 74.3 66.6 94.6 70.2 92.3 81.4 40.6 96.1 83.0 49.8 42.6 92.3 82.5 44.8 46.1 72.6 78.0 39.6 65.3 65.4 83.1 59.7 51.1 96.5 92.8 70.8 42.9 142.1 49.5 86.1 116.0 80.9 46.9 103.8 47.8 57.4 88.5 68.8 128.7 70.4 102.4 48.5 65.3 69.1 65.0 74.4 53.4 47.1 71.2 107.0 50.1 40.1 75.1 14.5 9.9 13.2 11.8 13.3 11.4 11.3 12.6 11.7 6.4 12.8 13.7 12.8 14.1 10.1 15.8 13.2 13.2 6.8 20.4 26.7 35.0 23.1 20.0 21.9 24.2 23.4 24.8 21.8 23.1 34.6 41.5 44.8 37.6 134.8 39.6 33.1 25.4 17.6 25.6 49.8 32.1 24.9 42.3 25.8 33.1 27.6 56.3 19.4 36.6 40.9 15.6 15.4 65.8 33.3 33.1 31.0 30.5 35.6 133.3 16.7 17.0 29.8 36.7 43.1 27.8 31.6 29.6 25.3 17.5 26.9 155.0 29.6 16.2 24.9 27.6 24.8 31.1 29.4 21.4 163.9 22.1 28.6 17.5 186.0 213.6 23.9 36.2 31.6 35.9 37.9 29.4 16.1 25.9 50.2 19.7 29.0 30.2 33.8 31.0 29.2 35.5 32.8 38.6 28.6 26.5 42.2 PPT2 ENSG00000221988 "Palmitoyl-protein thioesterase 2" Q9UMR5 6 32153441-32163678 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 33.6;Smooth muscle cells: 27.8;Syncytiotrophoblasts: 23.3" "Cancer enhanced" "Detected in all" "melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 21.3;HEK 293: 27.9;SK-MEL-30: 29.4" HPA000414 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA000414: " "unprognostic (1.90e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.03e-5)" "unprognostic (1.62e-1)" "unprognostic (6.75e-3)" "unprognostic (2.92e-3)" "unprognostic (6.41e-3)" "unprognostic (7.12e-2)" "unprognostic (2.56e-3)" "unprognostic (5.28e-3)" "unprognostic (1.12e-2)" "unprognostic (2.75e-3)" "unprognostic (5.09e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.24e-3)" 19.0 18.0 1.1 2.1 1.1 0.1 18.7 1.1 4.8 26.5 1.0 23.7 1.6 22.0 2.6 28.2 21.7 0.0 24.5 1.1 1.1 22.1 13.9 14.3 1.7 1.1 1.2 46.2 14.3 0.0 13.7 3.9 1.1 17.2 1.5 6.2 14.9 0.0 19.0 29.4 14.9 1.3 1.1 13.3 21.0 8.3 1.1 1.9 14.6 0.2 1.0 18.1 24.2 1.3 0.0 0.0 0.0 0.4 21.3 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.2 1.6 0.7 5.3 2.6 5.0 0.0 0.0 27.9 4.0 0.0 0.0 0.0 3.5 1.8 4.0 1.6 0.0 7.3 3.8 0.0 14.9 0.0 1.8 1.7 13.0 4.6 0.0 0.0 0.9 0.0 6.3 5.8 0.0 14.3 0.0 1.6 5.4 8.7 5.2 29.4 15.2 0.0 3.7 0.8 0.0 11.4 0.0 0.0 0.8 12.6 3.0 5.8 2.2 3.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.7 0.0 0.1 1.1 1.1 1.1 4.8 1.1 1.1 1.1 1.2 1.1 1.1 1.1 1.3 9.4 0.0 0.5 0.0 0.7 3.3 2.9 2.6 5.7 12.4 4.2 2.9 6.8 2.8 2.8 3.7 16.7 14.5 4.4 2.4 1.9 1.8 0.3 4.5 4.3 7.6 4.9 17.4 0.0 3.0 9.2 6.3 1.5 5.0 0.0 33.6 6.4 4.4 3.0 3.3 0.0 2.6 2.0 1.3 1.3 1.1 4.1 1.1 7.2 0.0 0.2 9.5 3.1 0.0 0.0 1.8 3.8 3.0 1.7 1.4 1.4 3.1 0.6 6.1 0.0 3.6 27.8 4.0 6.7 4.4 2.3 23.3 1.4 5.0 3.0 1.5 PRKAR1A "CNC1, PRKAR1, TSE1" ENSG00000108946 "Protein kinase cAMP-dependent type I regulatory subunit alpha" P10644 17 68511780-68551319 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 606.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019378, HPA049979" Approved Approved Cytosol NA NA 1800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB019378: , HPA049979: AB_2680980" "unprognostic (8.69e-2)" "unprognostic (6.97e-2)" "unprognostic (5.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.68e-1)" "unprognostic (4.39e-2)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (5.55e-2)" "unprognostic (8.56e-3)" "unprognostic (6.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" 125.9 158.2 72.0 124.1 83.2 57.1 118.4 76.7 119.1 151.2 97.3 70.0 51.7 145.5 122.3 98.5 141.3 125.2 430.0 89.0 102.1 164.3 150.8 163.7 111.4 85.6 91.8 202.8 63.1 300.2 88.0 164.3 105.0 114.5 79.1 132.2 169.7 137.6 250.6 63.8 58.7 132.1 71.7 121.7 86.9 130.8 91.8 109.4 173.6 147.4 103.6 136.4 67.6 93.5 95.5 180.0 225.9 136.1 294.6 331.7 33.9 125.7 257.9 192.2 168.6 70.5 125.5 96.3 84.3 276.7 196.8 77.2 168.8 204.2 273.8 65.8 60.4 149.1 154.0 233.0 213.0 115.8 160.2 239.1 207.4 222.3 185.9 215.0 324.6 80.8 68.5 147.2 236.4 181.0 128.2 60.9 83.9 97.7 121.4 88.1 373.6 106.7 292.4 204.3 81.8 110.3 115.4 207.6 496.8 208.5 162.8 161.1 232.2 269.4 127.6 123.3 119.0 121.6 93.5 142.4 163.0 107.8 171.8 149.6 108.3 189.4 48.6 101.0 48.8 42.8 35.9 43.6 105.9 32.3 32.1 35.9 208.2 76.1 120.9 34.7 50.9 113.5 72.0 83.2 76.7 119.1 89.0 102.1 85.6 91.8 105.0 71.7 91.8 93.5 134.1 147.4 263.4 38.5 126.0 142.8 100.1 136.8 116.7 99.6 106.8 65.4 606.2 81.5 156.4 252.0 66.7 77.4 127.4 58.1 178.1 80.7 407.9 142.9 116.4 131.8 136.9 52.5 76.1 52.0 86.8 163.2 78.5 110.3 185.0 78.2 158.1 120.7 146.1 139.7 78.4 53.3 136.3 176.2 171.1 93.7 133.6 151.1 192.1 46.9 142.3 125.1 78.2 57.3 76.3 74.6 51.5 190.7 95.6 85.3 27.1 210.1 307.7 59.9 85.5 123.2 210.9 219.8 54.2 122.4 131.7 82.5 117.3 184.0 43.9 112.8 PROS1 PROS ENSG00000184500 "Protein S" P07225 3 93873051-93980003 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 107.5;heart muscle: 116.6;liver: 283.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 83.1;Hepatocytes: 307.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 64.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 112.3;ASC TERT1: 100.1;HSkMC: 78.2;SK-MEL-30: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007724, HPA023974, CAB032610" Approved "Secreted to blood" NA NA 22500000000 5000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "CAB032610: AB_2237647, HPA007724: AB_1079688, HPA023974: AB_1855738" "unprognostic (2.00e-2)" "unprognostic (2.81e-2)" "unprognostic (9.21e-2)" "unprognostic (8.03e-3)" "unprognostic (3.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.48e-2)" "unprognostic (3.07e-1)" "unprognostic (5.18e-2)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.35e-4)" "unprognostic (4.90e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.42e-5)" 33.6 8.7 1.7 8.1 1.3 0.3 24.7 1.6 2.7 14.9 107.5 17.3 13.5 16.4 2.0 16.6 19.4 33.7 116.6 3.2 2.2 37.7 283.1 39.2 4.7 2.1 2.4 32.6 5.6 13.5 8.5 32.0 2.2 8.4 21.6 4.6 12.3 10.3 4.9 20.5 20.6 19.2 1.6 11.2 10.5 5.0 2.3 1.5 17.0 16.9 3.7 18.5 15.1 1.7 0.4 2.7 3.0 27.1 112.3 100.1 1.6 4.6 9.4 1.0 6.6 12.7 1.4 0.0 30.0 3.0 18.8 0.0 1.4 0.9 1.8 0.1 7.3 51.4 1.4 29.8 8.7 1.5 1.2 78.2 0.4 4.0 0.6 63.0 7.2 3.7 32.8 0.1 49.2 0.0 0.1 0.0 3.1 2.7 6.5 0.3 1.2 0.0 27.7 0.0 7.6 19.8 5.0 0.0 157.0 0.6 0.0 19.9 9.4 14.8 2.8 8.2 1.7 0.0 0.0 0.0 60.4 30.4 27.8 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 3.2 1.7 1.3 1.6 2.7 3.2 2.2 2.1 2.4 2.2 1.6 2.3 1.7 55.9 64.1 33.8 17.9 1.9 14.8 3.6 2.1 4.0 0.5 1.7 14.0 44.6 14.3 7.5 1.8 10.4 0.6 0.5 7.5 3.9 9.8 3.2 2.1 30.7 47.1 15.7 16.4 28.4 4.4 0.7 83.1 2.0 1.1 30.9 5.0 65.7 307.1 12.8 1.7 19.7 11.6 0.0 31.5 20.6 6.3 28.6 14.6 19.6 27.2 1.3 22.8 0.0 10.6 4.6 5.6 19.3 36.9 0.3 4.5 1.9 42.2 56.6 8.1 13.1 32.4 28.4 0.4 0.7 11.8 33.2 1.6 2.1 10.8 12.6 2.3 PRRT1 "C6orf31, DSPD1, IFITMD7, NG5" ENSG00000204314 "Proline rich transmembrane protein 1" Q99946 6 32148359-32153083 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 40.1;ovary: 11.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 67.5;Cardiomyocytes: 125.5;Granulosa cells: 181.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 38.4;cerebral cortex: 40.1;hippocampal formation: 37.0;white matter: 17.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.0;SK-MEL-30: 1.6;U-2 OS: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055149, HPA059099" Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "HPA055149: AB_2682717, HPA059099: AB_2732632" "unprognostic (1.40e-2)" "unprognostic (1.35e-1)" "unprognostic (2.10e-3)" "unprognostic (3.87e-3)" "unprognostic (2.89e-1)" "unprognostic (4.74e-2)" "unprognostic (5.51e-3)" "unprognostic (5.93e-2)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (8.08e-5)" "unprognostic (2.99e-1)" "unprognostic (2.22e-2)" "unprognostic (8.59e-2)" "unprognostic (9.40e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-2)" 1.6 2.2 38.4 0.3 6.4 0.0 2.0 0.0 40.1 2.7 0.0 2.9 0.6 2.3 0.0 1.5 3.6 0.1 1.6 37.0 4.8 3.1 0.9 1.3 0.1 3.4 2.1 11.9 0.6 0.3 5.6 0.2 2.2 3.1 0.0 1.3 0.9 0.6 0.4 2.0 1.8 0.0 0.0 0.9 2.0 1.3 6.5 0.0 1.9 0.0 0.0 2.4 2.4 17.5 0.0 0.1 0.0 0.5 0.2 0.1 0.2 0.8 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.8 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.4 6.4 0.0 40.1 37.0 4.8 3.4 2.1 2.2 0.0 6.5 17.5 3.2 0.0 0.0 4.9 0.5 4.0 8.0 3.4 14.8 67.5 1.8 3.0 125.5 10.0 1.2 1.8 10.4 6.7 1.7 2.2 1.9 0.1 1.3 1.3 2.3 6.7 9.0 4.2 12.6 0.0 1.0 7.8 4.6 0.5 0.0 181.6 5.0 3.5 1.0 32.0 10.9 5.5 0.0 0.8 2.1 1.2 6.2 1.9 3.6 6.5 0.2 16.0 1.0 3.5 5.0 0.2 3.4 6.4 0.8 3.6 5.5 0.1 3.7 8.7 0.0 3.6 8.0 0.8 1.6 3.8 2.7 3.6 2.2 8.1 4.1 4.8 PRSS33 EOS ENSG00000103355 "Serine protease 33" Q8NF86 16 2783953-2787948 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "fallopian tube: 4.7" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Melanocytes: 1.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 8.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 65 "eosinophil: 1296.1" "Lineage enriched" "Detected in many" 391 "granulocytes: 1296.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.7;hTERT-RPE1: 5.0;SK-MEL-30: 5.9;U-2 OS: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (4.78e-1)" "unprognostic (1.22e-1)" "unprognostic (8.99e-2)" "unprognostic (3.38e-2)" "unprognostic (3.10e-1)" "unprognostic (2.86e-2)" "unprognostic (1.16e-1)" "unprognostic (4.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.42e-2)" "unprognostic (2.28e-1)" "unprognostic (1.91e-1)" "unprognostic (2.70e-2)" 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 4.7 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.9 0.4 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.4 1296.1 0.2 0.4 0.2 0.1 0.1 0.0 0.2 0.2 0.1 0.3 2.1 3.3 0.3 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2792.8;Kupffer cells: 2427.0;Macrophages: 1916.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 5104.0;hTERT-RPE1: 6978.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" 1068.6 1192.2 831.4 874.2 946.7 834.2 683.8 873.7 831.7 1073.9 1023.0 667.1 475.6 879.3 951.2 605.5 724.7 1115.6 1413.3 830.5 1081.8 860.4 906.4 1118.6 956.1 957.6 894.0 1106.9 544.7 1167.5 563.5 869.3 885.3 773.9 625.5 665.2 580.9 936.8 1409.5 544.4 487.7 1138.6 1025.9 1045.9 664.0 489.1 1048.8 672.3 875.9 987.5 560.4 941.2 578.3 1325.1 455.9 847.4 540.4 1121.0 5104.0 2910.1 1900.2 799.9 2368.3 620.8 735.9 795.4 1131.9 245.6 1608.1 1321.6 1038.9 964.1 207.5 659.1 434.8 481.4 381.8 288.9 352.3 459.6 1970.7 188.8 1596.0 1871.8 1479.1 625.7 1177.6 6978.9 1128.1 345.8 420.5 1158.1 777.0 294.9 843.8 290.1 249.5 575.4 404.0 172.9 301.3 696.7 730.3 764.4 584.4 515.8 751.1 2248.3 3122.2 700.4 454.4 431.1 1467.0 861.8 610.0 587.1 670.5 1289.0 1038.7 435.4 1375.5 374.4 650.0 863.2 10095.9 1127.5 424.2 11615.6 349.8 466.7 342.9 368.8 3481.1 425.5 370.1 350.6 2890.4 365.8 10148.2 1758.2 422.8 15009.0 831.4 946.7 873.7 831.7 830.5 1081.8 957.6 894.0 885.3 1025.9 1048.8 1325.1 263.2 253.2 339.0 136.8 173.9 228.3 253.4 487.0 108.1 193.8 254.6 158.7 664.1 253.1 318.9 476.3 127.2 891.6 260.2 434.8 70.5 1043.6 19.3 147.0 246.6 311.4 261.9 160.5 86.1 456.1 872.6 623.8 187.6 195.2 398.1 210.8 426.9 509.2 2792.8 333.1 93.7 242.2 343.8 2427.0 779.7 54.1 458.6 1916.9 663.5 105.9 1528.9 495.6 182.3 92.5 117.6 357.7 298.3 551.8 503.0 244.8 370.6 311.6 297.2 164.3 276.1 273.6 263.8 55.2 126.3 137.2 198.0 1073.2 138.9 624.1 228.3 223.9 PSEN2 "AD3L, AD4, PS2, STM2" ENSG00000143801 "Presenilin 2" P49810 1 226870184-226927726 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ionocytes: 36.7;Syncytiotrophoblasts: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "unprognostic (3.40e-2)" "unprognostic (4.73e-3)" "unprognostic (2.94e-1)" "unprognostic (3.86e-2)" "unprognostic (6.54e-2)" "unprognostic (1.64e-3)" "unprognostic (4.72e-2)" "unprognostic (1.31e-1)" "unprognostic (9.98e-2)" "unprognostic (2.73e-2)" "unprognostic (8.25e-3)" "unprognostic (8.53e-3)" "unprognostic (8.45e-2)" "unprognostic (1.17e-1)" "unprognostic (8.36e-2)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" 11.2 19.8 9.7 7.5 9.8 1.6 10.6 12.5 10.7 9.7 10.7 15.2 10.5 15.9 9.0 10.3 13.4 8.3 14.0 9.4 10.6 13.5 12.6 11.5 8.0 9.8 10.9 12.8 45.5 18.1 17.1 9.0 10.8 14.9 8.1 7.4 13.0 13.6 26.5 10.1 13.8 10.4 8.5 15.6 11.5 13.5 10.7 3.3 9.5 16.7 5.0 13.5 9.7 9.7 14.1 24.5 7.2 21.9 10.0 3.5 10.2 12.4 26.5 16.9 12.9 13.8 21.5 1.0 17.0 16.8 10.5 7.9 12.1 11.9 6.7 13.6 20.7 8.7 10.5 12.0 15.4 7.5 15.7 9.1 13.9 18.9 10.4 11.2 6.9 0.7 18.1 6.4 10.0 14.7 0.4 8.2 20.5 22.0 16.0 0.4 22.6 26.4 15.9 13.4 11.3 18.3 9.7 30.6 51.6 18.4 26.5 13.1 8.5 11.2 8.9 9.9 15.2 25.6 45.0 0.9 21.5 2.5 15.7 37.4 8.7 18.4 4.5 9.7 5.1 7.4 1.5 4.6 11.4 3.1 0.7 2.0 1.6 20.0 30.2 0.8 2.4 5.2 9.7 9.8 12.5 10.7 9.4 10.6 9.8 10.9 10.8 8.5 10.7 9.7 11.0 16.0 10.8 2.6 3.9 1.7 4.5 4.0 1.8 6.2 6.6 4.1 12.9 15.7 4.7 5.5 0.0 15.9 1.3 5.9 1.9 13.0 2.5 4.5 3.0 10.0 6.0 6.1 4.2 18.0 4.1 5.9 7.7 5.2 14.5 10.1 19.2 8.4 17.2 16.8 4.5 5.1 36.7 7.2 6.5 1.3 7.2 8.2 33.8 5.6 18.9 21.2 2.1 2.5 1.5 15.2 7.8 13.2 9.9 5.3 13.8 7.2 4.9 5.8 6.6 9.4 10.6 1.5 6.1 3.8 1.8 45.8 2.9 6.6 4.3 4.6 PYGB ENSG00000100994 "Glycogen phosphorylase B" P11216 20 25248085-25298012 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 122.8;Distal enterocytes: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 407.8;SK-MEL-30: 528.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031067 Approved Approved Cytosol NA NA 14000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA031067: AB_2673722" "unprognostic (6.13e-2)" "unprognostic (5.98e-2)" "unprognostic (1.21e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.37e-4)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.23e-3)" "unprognostic (8.39e-3)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.22e-2)" "unprognostic (3.41e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.43e-4)" 50.8 36.4 78.2 27.7 77.9 14.1 61.1 84.1 82.4 37.0 35.4 140.9 27.0 51.9 21.4 106.6 37.8 39.1 163.9 77.3 74.9 43.7 14.6 32.1 19.1 85.4 80.8 25.9 25.4 18.1 61.5 11.5 81.2 107.9 72.6 25.4 125.1 106.3 18.7 85.3 44.8 59.8 84.7 22.6 51.3 25.2 80.3 18.4 45.2 10.5 17.3 154.2 53.0 84.8 31.5 220.1 39.1 38.3 97.9 182.7 28.7 62.2 80.9 51.4 43.0 50.1 38.0 37.1 71.8 83.6 96.1 123.9 44.5 165.8 27.9 21.1 27.5 29.5 18.6 86.9 115.7 44.7 40.0 107.1 152.4 130.5 191.3 63.5 66.6 23.0 16.5 91.4 73.0 87.1 45.1 34.6 35.2 38.2 407.8 33.7 71.0 49.8 280.5 56.8 58.4 36.5 42.7 74.0 528.7 31.0 51.9 28.4 147.4 60.3 36.5 65.1 128.7 35.2 58.8 14.4 67.9 34.8 335.3 4.6 14.1 7.1 10.2 19.4 9.9 5.4 8.1 9.2 14.5 4.6 10.3 12.9 3.3 11.2 23.4 7.1 9.6 23.4 78.2 77.9 84.1 82.4 77.3 74.9 85.4 80.8 81.2 84.7 80.3 84.8 10.0 9.6 34.6 43.1 8.7 11.9 23.1 20.7 22.2 35.8 31.6 43.6 122.8 11.5 14.6 25.8 37.5 7.1 10.7 185.2 11.7 17.6 3.5 12.7 17.2 13.5 28.2 8.6 22.9 16.5 7.2 15.3 40.2 21.6 6.3 16.2 8.9 5.8 10.8 18.5 26.9 47.3 57.0 13.8 10.7 9.2 27.4 18.5 35.6 15.0 16.6 21.3 15.5 11.6 19.1 27.0 68.5 86.5 22.9 17.6 20.9 11.1 11.9 9.3 0.0 13.5 23.1 2.0 8.5 15.3 10.1 4.4 12.9 20.3 72.0 9.7 PYURF PreY ENSG00000145337 "PIGY upstream reading frame" Q96I23 4 88520998-88523776 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036455 Uncertain Approved Nucleoplasm NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 32: Non-specific - Translation" Nucleoplasm "HPA036455: AB_10673388" "unprognostic (8.25e-2)" "unprognostic (9.14e-2)" "unprognostic (6.61e-2)" "unprognostic (2.03e-1)" "unprognostic (5.03e-2)" "unprognostic (7.23e-2)" "unprognostic (1.10e-2)" "unprognostic (8.84e-3)" "unprognostic (3.64e-1)" "unprognostic (1.48e-2)" "unprognostic (1.20e-2)" "unprognostic (2.35e-2)" "unprognostic (9.04e-3)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (4.78e-3)" 71.2 72.2 35.1 23.1 37.0 44.5 70.4 38.7 43.4 69.0 33.8 72.0 30.7 74.8 45.6 64.1 65.5 22.5 58.6 34.0 37.3 84.9 81.7 56.4 27.8 36.7 35.6 65.2 59.0 41.9 66.2 28.5 36.5 61.9 31.2 22.9 55.4 33.9 66.9 67.0 53.9 36.2 39.2 54.4 56.8 42.3 36.2 27.3 54.5 42.3 29.4 61.7 62.5 39.3 60.1 19.8 39.1 46.4 76.7 78.3 26.2 43.2 60.6 53.1 44.6 15.5 46.3 0.2 47.3 61.7 36.4 25.2 35.6 54.4 66.6 73.4 61.8 66.2 24.8 59.9 58.0 110.7 40.9 54.4 80.8 34.5 69.5 50.4 88.5 20.4 75.9 64.9 77.8 45.5 68.5 67.6 32.7 70.5 37.5 68.0 36.3 69.8 44.4 33.4 46.7 45.7 54.9 49.4 119.9 38.4 23.0 54.8 60.6 56.1 51.9 55.3 40.6 45.6 40.1 7.5 49.3 55.7 63.1 82.4 92.1 79.0 90.4 94.9 102.2 98.9 103.2 98.3 111.0 80.5 105.4 101.6 18.1 108.9 95.3 68.3 116.8 186.1 35.1 37.0 38.7 43.4 34.0 37.3 36.7 35.6 36.5 39.2 36.2 39.3 136.2 51.3 71.3 0.0 92.0 230.4 176.0 167.2 158.8 28.7 207.2 205.2 5.8 84.4 98.8 86.5 10.4 232.3 106.8 65.5 287.6 118.0 44.0 69.7 103.9 127.0 114.6 98.2 0.0 129.5 120.6 119.6 53.5 51.2 105.8 97.7 114.2 147.3 139.4 26.9 0.0 99.4 101.7 115.9 124.7 98.3 125.9 100.0 348.6 0.0 129.2 113.3 176.1 0.0 0.0 103.4 102.7 120.0 84.6 208.7 128.0 236.9 79.1 33.0 59.2 107.3 109.2 108.1 62.3 189.9 289.0 163.9 119.6 136.5 132.8 142.3 QDPR "DHPR, PKU2, SDR33C1" ENSG00000151552 "Quinoid dihydropteridine reductase" P09417 4 17460261-17512206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Oxidoreductase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 752.2;choroid plexus: 301.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 337.6;Muller glia cells: 387.2;Oligodendrocytes: 481.3;Proximal tubular cells: 527.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058951, HPA065649" Enhanced Approved Mitochondria NA NA 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA058951: AB_2683861, HPA065649: AB_2685526" "unprognostic (1.30e-2)" "unprognostic (4.29e-1)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (3.29e-3)" "unprognostic (3.80e-3)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (6.82e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.84e-6)" "unprognostic (1.58e-1)" "unprognostic (2.60e-1)" "unprognostic (9.01e-2)" "unprognostic (3.19e-1)" 66.6 74.3 515.1 10.2 720.1 15.1 26.4 696.9 571.9 15.8 301.8 21.2 25.6 16.5 40.1 15.6 17.3 17.7 43.4 457.6 578.5 110.1 197.2 23.3 11.9 663.0 752.2 18.3 28.8 49.9 32.7 11.8 688.6 28.7 17.0 40.1 36.3 19.5 108.6 16.2 23.9 17.9 524.9 14.3 23.7 12.4 602.6 13.6 22.1 61.2 13.3 14.5 15.1 663.7 33.1 62.5 30.2 35.8 66.1 32.3 41.5 43.2 22.3 47.5 41.6 52.2 46.4 12.2 28.0 30.3 50.8 18.4 40.3 58.4 33.7 35.3 7.3 34.8 33.4 128.3 37.3 46.2 2.9 40.8 35.6 31.6 40.3 25.9 24.5 33.2 37.0 29.0 50.6 19.2 65.0 77.8 44.8 36.7 45.4 27.0 21.0 52.2 48.2 17.5 47.1 64.3 31.9 6.7 156.6 35.0 15.7 19.0 37.7 23.6 41.1 26.5 38.2 43.1 67.7 85.3 52.0 43.1 41.7 0.3 38.9 3.0 31.3 61.3 29.8 18.6 33.1 32.3 48.3 18.3 37.4 32.6 1.1 29.8 48.4 115.1 20.3 34.4 515.1 720.1 696.9 571.9 457.6 578.5 663.0 752.2 688.6 524.9 602.6 663.7 20.3 28.9 31.5 10.7 14.8 20.0 21.3 32.2 18.8 36.2 37.6 28.3 74.4 50.1 19.5 38.6 8.4 69.6 22.8 13.7 109.5 41.1 1.0 11.8 19.1 17.2 174.3 30.1 23.1 23.4 34.2 27.1 27.5 17.8 25.4 42.3 20.7 337.6 80.3 82.4 21.9 31.1 34.6 38.1 23.9 4.8 22.7 32.2 152.9 12.2 23.4 387.2 16.5 15.1 481.3 16.9 11.6 38.0 23.6 23.2 41.4 527.2 6.2 31.4 26.3 27.5 25.4 3.3 58.9 29.7 16.1 18.3 18.5 90.0 35.7 17.3 QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37342827-37373322 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 170.3;epididymis: 104.0" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 217.0;Ionocytes: 138.4;Langerhans cells: 163.4;Melanocytes: 528.3" "Cancer enhanced" "Detected in all" "melanoma: 97.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 1527.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 1527.7" "Cell line enhanced" "Detected in many" "SCLC-21H: 117.1;SK-MEL-30: 426.8;U-266/84: 341.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" NA NA 390000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA008406: AB_1855981" "unprognostic (6.25e-3)" "unprognostic (6.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-3)" "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.78e-2)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (9.48e-3)" "unprognostic (3.62e-3)" 5.6 170.3 8.4 14.2 7.5 47.3 15.8 5.1 11.5 21.2 4.2 25.3 5.6 9.8 104.0 3.4 2.2 10.8 5.1 8.9 27.4 6.1 2.6 5.6 8.1 9.7 11.6 1.0 13.7 14.8 27.0 9.2 14.7 7.2 10.2 11.9 25.5 6.7 4.1 36.3 4.5 8.3 7.8 13.9 7.6 2.0 20.3 5.1 3.8 2.8 12.5 15.2 4.6 6.7 1.0 40.7 0.1 0.0 6.0 13.3 0.1 6.6 86.5 6.4 10.1 2.9 7.1 0.2 3.0 32.6 72.9 0.1 2.7 0.6 10.3 0.6 76.0 18.7 0.3 7.7 0.6 3.0 0.1 8.5 0.0 47.3 0.2 0.4 26.2 0.0 0.0 0.0 0.2 4.5 0.0 1.7 0.6 0.3 0.0 0.0 0.0 0.8 42.6 10.9 117.1 0.2 6.4 1.4 426.8 8.0 0.7 2.9 19.4 0.0 0.2 0.1 0.6 15.3 341.7 0.3 25.8 0.3 0.0 9.8 344.8 3.2 0.4 38.7 1.0 2.6 0.6 0.5 124.7 1.2 0.5 0.3 1527.7 0.2 3.3 2.4 0.1 169.8 8.4 7.5 5.1 11.5 8.9 27.4 9.7 11.6 14.7 7.8 20.3 6.7 1.8 3.2 2.3 0.3 12.5 39.0 13.6 40.0 2.2 21.8 7.9 8.5 1.1 1.5 17.7 22.0 2.1 0.7 0.8 6.1 1.9 45.4 0.6 2.6 24.7 17.5 217.0 1.7 8.5 2.4 6.1 26.7 3.1 4.0 55.3 1.6 22.5 0.3 20.5 43.7 7.3 6.6 138.4 21.2 163.4 2.9 3.1 26.8 528.3 6.5 64.3 0.8 3.1 3.0 1.3 31.8 1.8 23.7 26.0 9.1 0.2 11.7 4.3 3.2 13.1 0.6 6.6 1.7 0.7 0.6 14.5 4.7 5.6 5.0 7.3 5.8 RAB17 ENSG00000124839 "RAB17, member RAS oncogene family" Q9H0T7 2 237574322-237601614 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.7;liver: 107.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Distal tubular cells: 137.0;Hepatocytes: 121.7;Proximal enterocytes: 222.5;Proximal tubular cells: 170.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 42.4;Hep G2: 39.9;MCF7: 52.0;SK-BR-3: 48.1;SK-MEL-30: 86.7;T-47d: 34.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA035176 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035176: AB_10696368" "unprognostic (8.66e-2)" "unprognostic (1.13e-1)" "unprognostic (1.44e-3)" "unprognostic (9.14e-2)" "unprognostic (2.48e-3)" "unprognostic (1.26e-3)" "unprognostic (1.33e-1)" "unprognostic (5.36e-2)" "unprognostic (3.49e-2)" "unprognostic (2.68e-2)" "prognostic favorable (4.14e-4)" "unprognostic (5.87e-2)" "prognostic favorable (3.33e-13)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (3.44e-1)" "prognostic favorable (2.51e-4)" 0.8 1.0 0.9 1.6 0.6 0.4 15.0 0.6 1.3 6.7 25.8 16.4 76.7 2.3 19.4 2.1 11.1 14.7 1.5 2.2 0.7 49.8 107.6 23.1 0.4 0.8 0.7 0.6 38.7 36.9 3.0 13.8 0.7 7.0 15.6 4.2 34.8 15.3 1.4 0.9 73.7 1.0 0.6 0.5 33.5 0.7 0.9 1.0 33.4 0.0 0.8 3.8 0.3 0.7 9.5 0.3 0.0 17.7 0.1 0.2 42.4 0.2 0.1 0.0 0.1 28.7 26.6 0.0 5.6 0.2 0.1 0.4 0.0 12.5 0.2 0.0 0.0 0.0 0.1 39.9 0.0 0.2 0.0 0.0 7.8 0.0 0.9 0.7 0.0 0.1 0.0 0.0 1.0 52.0 0.0 0.6 0.5 28.6 0.1 1.1 0.0 3.4 13.7 25.1 10.5 0.1 0.0 48.1 86.7 9.4 34.8 0.7 0.0 0.2 0.6 0.1 0.1 0.1 1.2 0.0 0.1 2.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.6 1.3 2.2 0.7 0.8 0.7 0.7 0.6 0.9 0.7 1.2 60.9 34.3 0.3 0.5 1.8 3.4 3.3 22.8 1.7 32.2 18.3 1.0 65.8 11.9 46.0 106.3 16.0 0.1 49.6 137.0 40.0 0.0 18.2 1.6 1.8 30.3 0.0 0.8 28.0 3.8 0.7 29.0 22.1 0.0 0.4 2.5 121.7 1.9 0.0 1.5 23.9 24.4 2.2 0.6 0.7 8.7 1.3 5.4 0.0 0.6 0.2 0.0 1.0 0.1 27.9 50.1 3.8 0.1 5.3 222.5 170.2 13.7 0.6 0.0 0.3 0.7 0.0 0.2 6.6 0.6 12.3 1.3 0.7 21.9 6.5 RAB43 "ISY1, RAB11B, RAB41" ENSG00000172780 "RAB43, member RAS oncogene family" Q86YS6 3 129087569-129122801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 46.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.0;Gastric mucus-secreting cells: 5.6;Plasma cells: 9.2;Squamous epithelial cells: 2.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.2" "Group enriched" "Detected in many" 5 "granulocytes: 11.2;T-cells: 2.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046840, HPA060085" Enhanced Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA046840: , HPA060085: AB_2684199" "unprognostic (3.01e-1)" "unprognostic (1.14e-2)" "unprognostic (3.08e-1)" "unprognostic (1.01e-1)" "unprognostic (5.08e-2)" "unprognostic (1.91e-1)" "unprognostic (9.36e-2)" "unprognostic (3.17e-2)" "unprognostic (4.16e-1)" "unprognostic (8.68e-2)" "unprognostic (3.14e-1)" "unprognostic (3.08e-1)" "unprognostic (2.46e-2)" "unprognostic (9.32e-2)" "unprognostic (5.82e-3)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" 7.6 8.3 9.5 10.4 9.7 22.3 7.1 11.6 8.1 7.3 9.3 7.9 8.0 6.6 2.9 5.9 7.3 9.4 4.2 7.9 5.8 10.4 46.9 14.8 17.4 10.0 7.5 9.9 10.3 5.2 6.7 3.9 8.4 9.9 2.6 0.7 10.2 5.0 1.8 4.0 6.9 2.7 7.3 10.9 8.1 7.5 7.1 12.9 22.7 1.4 4.6 7.3 4.0 6.7 22.4 6.0 1.4 5.7 2.7 1.2 8.3 7.6 5.1 4.4 3.5 9.4 9.4 0.6 17.1 5.7 5.9 9.2 0.5 8.8 1.0 11.2 5.6 1.5 1.1 12.5 25.9 5.1 12.7 7.1 5.4 2.2 0.5 1.9 8.7 13.0 2.5 10.8 6.1 9.7 5.0 9.8 7.0 5.2 10.5 10.8 3.2 6.6 14.1 18.7 0.4 2.7 3.3 7.0 14.4 2.2 3.0 5.3 12.5 9.3 6.4 7.6 2.9 16.9 9.8 3.6 8.5 1.0 10.3 0.4 1.2 2.3 1.5 1.5 0.7 0.5 1.5 1.2 0.6 1.0 2.8 2.4 11.2 1.4 0.7 0.9 2.4 1.0 9.5 9.7 11.6 8.1 7.9 5.8 10.0 7.5 8.4 7.3 7.1 6.7 0.2 0.0 0.0 0.0 0.7 0.0 0.1 0.0 12.0 0.0 0.2 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.3 0.4 0.0 0.8 0.0 0.3 0.6 0.4 0.0 0.0 0.0 0.2 0.1 0.5 5.6 0.5 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 9.2 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.4 0.2 0.1 2.5 0.1 0.1 1.2 0.2 0.3 0.1 RAB7A "CMT2B, RAB7" ENSG00000075785 "RAB7A, member RAS oncogene family" P51149 3 128693669-128825942 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Host-virus interaction, Lipid degradation, Lipid metabolism, Protein transport, Transport" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006964, CAB037131" Supported Supported Lysosomes NA NA 5700000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Lysosomes "CAB037131: AB_477460, HPA006964: AB_1856015" "unprognostic (1.99e-2)" "unprognostic (9.03e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (1.45e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (9.89e-6)" "unprognostic (2.15e-2)" "unprognostic (2.38e-1)" "unprognostic (3.50e-1)" "prognostic unfavorable (4.63e-4)" "unprognostic (4.69e-1)" "unprognostic (6.73e-3)" "unprognostic (1.88e-1)" "unprognostic (1.97e-1)" "unprognostic (3.03e-3)" "unprognostic (5.64e-3)" 170.6 157.1 120.1 101.4 132.2 99.9 149.5 133.4 159.4 138.3 123.7 128.9 108.3 137.4 143.0 188.2 110.1 109.7 186.8 128.9 138.4 131.8 145.2 152.9 108.8 138.8 142.0 122.7 88.6 155.9 101.5 117.5 139.4 101.3 126.0 103.8 133.3 63.9 332.4 164.9 116.8 124.0 135.9 123.0 114.9 61.5 140.3 124.6 122.5 249.7 136.6 144.4 143.4 159.0 280.2 95.5 146.0 78.3 300.6 94.0 126.0 252.8 183.9 164.4 158.8 170.1 179.2 134.2 163.2 236.2 289.9 163.4 175.2 248.6 99.2 149.4 111.7 294.3 83.6 165.8 303.0 269.4 182.5 243.7 104.0 176.7 204.4 220.7 89.2 114.4 143.4 148.0 108.1 213.1 176.8 294.6 121.4 294.8 144.8 140.2 130.7 170.4 85.7 205.4 105.8 138.5 142.1 194.7 405.4 174.9 180.3 254.8 202.9 192.7 98.0 325.7 125.9 184.4 187.0 192.0 312.7 212.1 235.5 194.9 176.8 213.6 92.1 192.3 92.3 93.2 97.4 94.5 200.0 85.8 94.8 93.6 374.2 128.8 204.0 81.8 120.7 201.3 120.1 132.2 133.4 159.4 128.9 138.4 138.8 142.0 139.4 135.9 140.3 159.0 154.4 89.8 81.8 66.9 109.9 296.7 331.2 218.1 104.7 66.0 112.8 73.0 110.7 90.1 129.4 132.4 18.8 230.0 92.3 222.1 240.7 259.6 11.2 90.8 90.8 165.3 96.9 111.3 83.9 198.9 283.4 172.5 79.0 142.4 146.2 46.5 142.8 127.9 403.9 74.0 82.5 122.8 219.7 208.6 379.9 19.6 133.6 242.8 339.7 99.3 220.9 154.6 121.5 80.9 111.4 303.7 185.0 157.2 79.9 279.2 172.7 332.3 118.7 37.6 138.1 107.7 160.5 116.4 100.4 122.8 308.0 497.9 107.7 109.6 103.5 324.6 RAMAC "C15orf18, FAM103A1, HsT19360, MGC2560, RAM, RAMMET" ENSG00000169612 "RNA guanine-7 methyltransferase activating subunit" Q9BTL3 15 82986210-82991057 "Predicted intracellular proteins" "mRNA capping, mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 108.2;Extravillous trophoblasts: 82.2;Hofbauer cells: 69.4;Syncytiotrophoblasts: 92.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041923, HPA041948" Supported Supported Nucleoplasm No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041923: AB_10796467, HPA041948: AB_10797270" "unprognostic (1.51e-1)" "unprognostic (1.16e-2)" "unprognostic (5.30e-2)" "unprognostic (1.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (1.96e-1)" "unprognostic (2.58e-1)" "unprognostic (2.32e-2)" "unprognostic (3.63e-3)" "unprognostic (2.09e-2)" "unprognostic (4.72e-2)" "unprognostic (7.46e-3)" "unprognostic (9.57e-2)" "unprognostic (2.72e-2)" "unprognostic (9.47e-2)" "unprognostic (2.45e-1)" 12.9 14.8 10.9 16.4 11.4 30.1 26.1 12.9 14.8 16.6 11.6 18.4 14.5 18.2 30.1 24.1 19.5 13.4 14.8 11.6 12.2 16.8 24.2 13.0 23.0 11.6 11.3 20.6 16.4 18.8 12.9 25.9 11.3 18.0 19.3 19.9 18.2 15.2 29.1 21.5 13.4 16.8 11.6 14.1 19.0 15.6 11.1 23.3 18.2 20.2 28.9 20.8 15.6 11.6 34.1 44.7 44.3 27.1 23.5 15.9 32.7 33.7 33.5 37.6 30.4 49.4 42.9 16.8 45.8 29.2 45.4 37.9 77.1 32.4 40.6 42.0 49.7 52.7 22.7 58.7 33.3 38.0 44.9 34.9 61.4 30.6 38.5 28.7 23.6 28.5 62.8 33.9 39.8 35.7 29.5 48.3 52.0 45.0 21.1 33.4 38.2 26.0 49.0 64.6 41.1 42.0 34.6 36.7 87.0 71.5 58.6 47.9 16.8 27.5 34.9 26.1 48.8 53.1 104.0 41.8 25.2 50.7 34.5 138.6 59.2 98.2 47.9 57.0 51.8 64.8 54.1 52.3 56.1 61.1 53.9 53.4 117.4 70.4 62.8 51.6 69.9 65.9 10.9 11.4 12.9 14.8 11.6 12.2 11.6 11.3 11.3 11.6 11.1 11.6 18.3 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.2 19.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 82.2 10.0 0.0 0.0 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 92.9 2.7 0.0 0.0 0.0 RASSF3 ENSG00000153179 "Ras association domain family member 3" Q86WH2 12 64507001-64697564 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 149.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 124.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 124.1" "Cell line enhanced" "Detected in all" "SK-MEL-30: 145.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022664, CAB034035, HPA038469" Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB022664: , CAB034035: AB_2176848, HPA038469: AB_10671743" "unprognostic (1.63e-1)" "unprognostic (1.33e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (2.37e-2)" "unprognostic (2.55e-3)" "unprognostic (3.73e-1)" "unprognostic (2.37e-1)" "unprognostic (6.21e-2)" "unprognostic (3.66e-2)" "unprognostic (1.49e-1)" "unprognostic (1.45e-3)" "unprognostic (7.16e-2)" "unprognostic (2.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.59e-2)" 33.1 22.9 13.8 43.3 9.3 17.3 14.9 7.1 9.5 19.4 33.0 106.6 21.1 23.9 15.1 36.8 13.2 29.3 44.3 7.6 9.2 6.9 10.9 32.5 37.0 11.4 20.5 19.6 13.1 3.3 4.6 39.6 13.6 33.0 42.0 1.5 35.6 48.7 45.0 6.8 26.3 60.1 11.4 47.6 34.5 13.5 22.1 15.4 6.5 13.1 33.2 50.3 14.1 13.4 28.1 30.9 9.6 18.6 10.2 14.7 58.3 11.9 61.8 15.8 18.6 22.3 28.9 43.6 24.8 8.6 19.0 12.1 29.6 12.5 19.0 35.5 11.3 28.6 13.0 25.5 27.9 30.5 19.3 10.0 10.7 36.2 26.7 46.1 68.0 20.7 15.4 21.0 18.7 26.5 20.2 19.9 21.4 65.8 18.8 32.5 30.9 18.4 20.8 33.6 21.7 22.7 20.0 3.8 145.5 23.0 17.3 19.0 98.7 12.8 15.6 13.5 13.1 19.5 22.0 28.0 15.4 26.2 37.8 19.6 16.6 12.5 13.2 17.7 11.1 14.1 19.4 14.9 9.1 10.1 19.1 20.3 124.1 12.0 17.7 8.4 22.1 2.8 13.8 9.3 7.1 9.5 7.6 9.2 11.4 20.5 13.6 11.4 22.1 13.4 30.7 3.2 15.4 4.2 32.7 16.3 15.0 5.5 2.8 0.0 12.4 13.7 56.5 30.0 8.9 5.5 0.0 35.5 39.0 67.4 0.0 12.4 0.3 14.4 4.1 31.2 26.4 16.4 8.7 21.2 19.1 14.5 20.9 28.3 6.3 4.7 20.7 4.6 24.1 0.0 16.2 15.8 2.0 69.9 149.3 0.8 2.5 55.7 48.0 49.6 72.7 2.8 32.0 3.5 4.8 24.0 14.5 14.3 9.8 25.5 13.3 1.7 3.9 0.2 13.1 9.2 27.0 0.6 19.3 5.9 11.9 19.7 30.7 1.6 20.7 21.1 RBM4 "LARK, RBM4A, ZCCHC21, ZCRB3A" ENSG00000173933 "RNA binding motif protein 4" Q9BWF3 11 66638667-66668374 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, RNA-mediated gene silencing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042174, HPA047849" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "HPA042174: AB_2677885, HPA047849: AB_2680180" "unprognostic (8.43e-2)" "unprognostic (1.55e-1)" "unprognostic (2.17e-1)" "unprognostic (1.53e-2)" "unprognostic (9.46e-3)" "unprognostic (1.13e-1)" "unprognostic (5.41e-3)" "unprognostic (6.42e-2)" "unprognostic (4.34e-3)" "unprognostic (1.57e-1)" "unprognostic (1.22e-1)" "unprognostic (4.42e-2)" "unprognostic (2.53e-1)" "unprognostic (2.13e-1)" "unprognostic (2.27e-1)" "unprognostic (4.76e-2)" "unprognostic (3.07e-3)" 82.6 111.5 60.8 71.0 63.3 131.5 75.8 81.1 66.7 90.8 69.4 96.1 67.8 87.1 90.3 100.3 79.4 59.0 75.6 61.5 67.1 119.8 82.3 77.4 97.5 59.0 58.5 103.6 115.5 77.2 86.1 72.8 58.9 95.9 62.6 74.4 89.1 60.0 96.6 80.9 83.6 69.1 61.1 104.8 98.4 74.3 69.5 109.8 85.7 72.4 99.1 84.2 84.1 65.4 127.2 163.6 246.5 136.4 90.1 95.6 153.9 128.6 106.1 134.1 97.3 281.5 160.9 161.1 174.4 132.3 120.5 136.4 263.5 159.1 142.9 162.1 138.4 220.7 163.5 170.3 173.1 152.8 91.9 138.8 134.3 158.6 213.9 136.4 184.3 155.0 180.1 115.0 147.3 263.3 252.9 157.9 309.7 246.8 176.0 234.2 224.6 181.7 180.7 199.5 204.5 149.5 227.1 168.6 379.9 163.8 315.3 154.4 180.9 140.4 124.0 86.5 107.3 143.9 162.5 258.8 109.9 118.3 205.8 210.0 119.4 131.3 135.5 123.2 122.3 119.3 139.8 149.9 116.2 130.4 147.5 149.8 137.5 155.4 144.0 103.6 194.3 159.1 60.8 63.3 81.1 66.7 61.5 67.1 59.0 58.5 58.9 61.1 69.5 65.4 19.7 28.9 42.2 8.1 64.0 17.8 61.4 36.3 112.7 58.2 24.2 12.7 4.6 15.7 36.5 20.2 93.8 36.2 48.7 16.6 15.6 25.1 39.8 26.6 28.0 28.5 34.7 42.5 23.9 23.1 30.1 33.6 53.0 30.7 36.8 38.1 25.7 11.1 14.5 62.2 21.4 15.5 32.6 18.8 29.2 9.3 27.4 27.5 19.6 7.5 28.8 15.9 69.0 15.1 18.8 19.6 23.6 20.3 60.2 62.6 32.9 10.6 41.1 90.0 19.7 29.7 28.3 41.1 40.1 68.6 22.3 43.8 66.3 42.4 24.8 65.5 RCAN1 DSCR1 ENSG00000159200 "Regulator of calcineurin 1" P53805 21 34513142-34615113 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 256.2;parathyroid gland: 453.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 245.5;Endometrial ciliated cells: 336.9;Glandular and luminal cells: 504.9" "Cancer enhanced" "Detected in all" "glioma: 41.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "SK-MEL-30: 1323.8;WM-115: 815.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037218, HPA068436" Enhanced Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" Cytosol "CAB037218: AB_2179743, HPA068436: " "unprognostic (3.83e-2)" "unprognostic (4.40e-1)" "unprognostic (1.04e-1)" "unprognostic (7.55e-2)" "unprognostic (9.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.82e-3)" "unprognostic (5.27e-2)" "unprognostic (7.99e-2)" "unprognostic (4.83e-2)" "unprognostic (2.71e-1)" "unprognostic (2.04e-1)" "unprognostic (4.07e-3)" "unprognostic (1.54e-3)" "unprognostic (1.68e-1)" "unprognostic (2.45e-2)" "unprognostic (2.60e-3)" 58.5 22.0 59.0 50.3 68.2 6.3 65.0 64.6 79.8 86.4 69.9 39.0 31.6 28.7 8.9 24.5 12.4 57.4 61.6 57.5 65.7 89.8 256.2 38.6 12.9 68.1 65.3 8.7 64.1 453.5 30.7 95.6 68.3 24.1 39.5 13.1 20.4 15.1 34.4 29.1 27.6 48.7 67.4 14.6 34.9 10.5 72.7 82.2 61.0 31.8 9.7 101.3 20.9 75.0 47.7 9.5 47.9 29.6 25.7 15.9 29.1 175.8 181.3 71.1 70.5 54.1 44.7 0.8 8.1 103.4 139.5 4.1 34.4 35.6 94.5 26.8 21.2 9.5 16.5 25.8 98.1 15.3 28.9 41.4 31.9 84.4 58.7 17.9 23.8 32.5 18.1 45.7 47.7 23.1 145.4 12.2 27.4 48.0 23.5 53.9 37.5 22.2 22.8 81.1 23.0 10.1 128.4 82.2 1323.8 43.3 111.4 25.4 25.8 237.5 24.7 39.9 43.1 38.9 26.4 8.5 77.4 44.4 815.5 0.0 1.1 5.0 0.7 2.1 1.0 1.1 0.8 0.7 1.6 0.8 0.3 0.7 0.5 0.1 2.4 3.0 1.1 0.5 59.0 68.2 64.6 79.8 57.5 65.7 68.1 65.3 68.3 67.4 72.7 75.0 158.3 96.1 52.4 15.3 8.2 94.6 20.7 20.5 38.1 19.4 245.5 142.4 24.9 21.5 32.7 206.0 27.1 10.9 11.8 204.9 21.5 82.0 48.3 336.9 46.4 175.4 3.6 7.4 28.3 18.9 15.3 60.3 23.4 504.9 8.8 3.9 25.0 187.8 58.9 3.3 54.2 30.7 4.1 19.6 74.0 13.1 7.2 39.8 56.9 15.9 29.5 10.9 3.1 41.7 71.3 26.3 140.5 9.8 6.1 16.3 41.2 142.3 14.1 7.5 0.0 30.3 68.9 10.8 2.6 12.3 79.3 11.1 11.5 10.5 16.3 50.4 RCE1 "FACE-2, FACE2, hRCE1, RCE1A, RCE1B" ENSG00000173653 "Ras converting CAAX endopeptidase 1" Q9Y256 11 66842835-66846552 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074124 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "HPA074124: " "unprognostic (1.11e-1)" "unprognostic (7.23e-2)" "unprognostic (1.15e-1)" "unprognostic (8.16e-3)" "unprognostic (3.11e-1)" "unprognostic (6.40e-3)" "unprognostic (1.98e-3)" "unprognostic (7.69e-3)" "unprognostic (1.39e-1)" "unprognostic (9.14e-3)" "unprognostic (2.35e-3)" "unprognostic (5.31e-3)" "unprognostic (1.06e-1)" "unprognostic (4.48e-3)" "unprognostic (2.17e-2)" "unprognostic (1.04e-1)" "unprognostic (4.28e-2)" 10.1 10.9 14.9 7.2 15.1 20.9 9.3 17.9 18.2 10.7 13.7 13.3 10.1 8.4 5.9 19.9 8.9 8.6 7.3 14.7 14.9 25.7 7.9 8.9 9.9 14.0 14.1 10.8 15.5 9.5 13.9 11.8 14.2 12.0 8.2 10.0 12.6 6.1 4.4 19.9 12.4 5.9 13.5 12.0 12.0 13.5 15.5 9.5 7.0 4.2 6.1 11.9 12.9 14.6 22.7 24.5 14.7 13.8 9.0 7.8 32.3 11.6 11.2 17.7 15.8 46.6 47.2 17.2 21.8 11.1 29.3 39.6 17.1 17.4 10.2 20.7 19.3 15.5 17.0 18.0 31.7 20.3 22.0 12.6 32.7 19.9 17.6 13.7 14.6 23.5 21.7 26.0 9.0 42.8 28.2 38.3 43.5 43.1 24.0 22.9 11.0 34.1 19.5 12.0 18.3 16.5 16.8 22.3 74.1 14.3 26.2 16.3 9.7 24.2 18.7 26.4 18.5 14.6 15.2 19.6 16.4 20.8 18.4 23.1 21.1 14.6 17.1 24.0 15.6 15.3 14.7 22.1 18.9 12.0 11.8 17.8 7.2 14.3 21.5 29.1 6.7 17.8 14.9 15.1 17.9 18.2 14.7 14.9 14.0 14.1 14.2 13.5 15.5 14.6 12.5 0.0 4.8 4.2 16.9 31.2 26.6 46.2 14.2 9.2 16.4 20.6 1.8 10.0 20.3 16.5 29.2 54.6 24.9 12.4 3.9 24.3 10.1 11.3 12.5 12.2 10.7 10.7 7.7 27.4 65.0 12.0 11.7 17.1 8.2 13.3 8.2 3.0 22.8 3.3 6.2 16.0 26.4 8.9 15.1 20.2 6.8 13.3 14.2 3.7 12.9 6.4 9.2 6.0 4.0 30.0 18.0 6.4 14.5 19.6 23.2 7.4 8.9 18.0 13.1 5.6 32.1 9.7 25.7 17.1 24.9 58.6 19.1 10.3 16.2 23.9 RETREG2 "C2orf17, FAM134A, MAG-2, MGC3035" ENSG00000144567 "Reticulophagy regulator family member 2" Q8NC44 2 219176225-219185475 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 42.1;Collecting duct cells: 46.0;Ductal cells: 43.8;Exocrine glandular cells: 48.3;Pancreatic endocrine cells: 40.4;Proximal tubular cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011170, HPA011844, HPA075910" Approved Approved Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA011170: AB_1845713, HPA011844: AB_2668544, HPA075910: " "unprognostic (2.63e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (7.95e-4)" "unprognostic (1.03e-1)" "unprognostic (2.88e-2)" "unprognostic (2.58e-3)" "prognostic unfavorable (1.49e-4)" "unprognostic (8.74e-2)" "unprognostic (9.61e-2)" "unprognostic (1.34e-2)" "unprognostic (4.37e-2)" "unprognostic (2.36e-1)" "unprognostic (4.29e-3)" "unprognostic (4.45e-2)" "unprognostic (4.47e-2)" "unprognostic (1.53e-2)" "unprognostic (3.70e-2)" 34.4 47.6 73.6 26.5 74.1 47.4 34.1 73.2 90.1 42.7 66.1 41.3 31.7 35.1 45.9 38.5 38.4 32.1 24.6 74.9 76.6 51.8 57.2 29.7 34.3 77.4 77.3 51.9 52.4 76.6 43.7 28.3 77.2 36.9 38.5 50.6 39.8 29.7 24.9 45.0 36.7 33.9 76.5 38.2 42.9 104.0 78.8 34.3 44.6 27.7 34.6 37.7 35.9 78.0 34.6 36.2 30.5 46.5 113.2 47.7 32.5 41.4 71.3 49.4 42.7 36.3 58.1 28.1 40.4 78.5 101.4 43.3 37.1 37.1 54.1 39.5 31.0 37.5 51.2 61.1 64.7 41.1 49.6 52.0 95.5 55.5 53.3 84.7 45.2 29.9 26.3 62.8 69.3 50.9 24.8 44.4 22.6 44.0 41.5 31.4 33.8 22.7 41.1 40.3 43.6 44.9 26.7 50.8 98.4 47.4 42.4 44.9 36.0 55.0 29.4 78.6 31.5 63.4 39.3 31.5 57.5 40.3 31.0 12.5 6.3 6.3 9.3 8.3 8.3 8.3 7.4 9.5 4.3 5.7 6.6 8.8 23.5 5.2 8.1 6.6 9.6 3.6 73.6 74.1 73.2 90.1 74.9 76.6 77.4 77.3 77.2 76.5 78.8 78.0 22.4 16.0 13.7 0.0 7.9 0.0 0.0 0.0 0.0 0.0 42.1 32.0 0.0 0.0 6.2 46.0 0.0 31.1 21.1 0.0 21.5 43.8 0.0 21.4 19.3 8.6 0.0 0.0 0.0 48.3 37.2 11.9 0.0 30.5 5.1 29.2 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 11.4 0.0 0.0 0.0 0.0 40.4 0.0 0.0 5.7 0.0 0.0 42.3 2.2 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 30.1 8.2 24.2 0.0 0.0 RFNG ENSG00000169733 "RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q9Y644 17 82047902-82051831 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HHSteC: 69.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011564, HPA031673" Uncertain Approved Nucleoplasm No No 1100000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA011564: AB_1079803, HPA031673: AB_2673989" "unprognostic (4.17e-3)" "unprognostic (7.60e-3)" "unprognostic (2.87e-3)" "unprognostic (2.49e-1)" "unprognostic (2.05e-1)" "unprognostic (2.65e-2)" "unprognostic (1.62e-1)" "unprognostic (9.86e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "prognostic favorable (4.81e-4)" "unprognostic (1.20e-1)" "unprognostic (6.96e-3)" "unprognostic (1.77e-1)" "unprognostic (2.16e-1)" "unprognostic (6.93e-2)" "unprognostic (4.14e-2)" 28.3 24.3 9.9 3.8 9.7 10.2 24.6 8.5 11.8 25.5 7.8 26.5 11.1 25.3 1.6 24.1 23.0 10.9 19.5 8.7 9.0 22.9 78.5 18.7 5.4 10.4 9.3 29.7 42.6 11.1 20.0 5.9 9.5 23.5 3.2 1.4 22.0 6.9 45.4 27.1 16.7 7.7 9.0 14.9 27.7 23.2 9.6 4.6 19.8 10.5 2.7 24.0 18.6 9.7 20.3 19.2 5.6 19.1 13.9 11.8 24.4 18.5 10.1 8.2 6.2 11.6 13.7 4.5 13.0 29.1 17.4 10.8 3.9 15.8 1.5 6.0 19.7 6.7 4.4 48.5 69.3 2.4 14.2 22.5 9.9 14.7 24.9 16.5 15.8 15.2 8.5 16.9 6.6 24.1 15.1 6.5 5.5 13.5 20.1 10.2 7.0 10.6 9.5 11.8 9.7 24.9 7.1 10.7 54.7 6.2 32.1 13.7 6.1 13.1 17.9 12.7 10.2 22.9 4.5 5.0 16.8 4.4 11.7 1.0 1.9 2.0 1.7 0.5 0.6 1.0 1.1 1.6 1.4 1.2 1.1 0.6 0.7 0.2 0.7 1.1 2.5 0.6 9.9 9.7 8.5 11.8 8.7 9.0 10.4 9.3 9.5 9.0 9.6 9.7 24.3 6.4 12.4 30.7 7.6 9.7 11.9 8.3 6.8 26.9 33.3 35.4 12.8 18.6 5.6 23.9 25.0 5.5 14.2 20.9 7.9 7.8 3.7 14.9 24.4 12.1 11.4 5.7 20.7 15.1 3.3 27.2 18.8 19.0 1.3 52.5 21.8 47.1 9.6 11.8 20.3 14.0 12.2 15.2 6.3 13.3 21.8 14.7 10.6 16.9 6.2 29.8 3.1 20.6 13.5 12.4 16.3 19.9 4.9 15.9 14.0 31.3 6.8 27.8 0.0 28.0 19.4 14.4 6.2 9.0 10.2 3.7 10.4 32.8 13.5 8.7 RILPL1 FLJ39378 ENSG00000188026 "Rab interacting lysosomal protein like 1" Q5EBL4 12 123470054-123533719 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 62.4;skeletal muscle: 88.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Oligodendrocytes: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041314 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA041314: AB_10795587" "unprognostic (2.21e-1)" "unprognostic (1.26e-1)" "unprognostic (3.71e-2)" "unprognostic (5.36e-2)" "unprognostic (3.12e-2)" "unprognostic (2.99e-3)" "unprognostic (1.94e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (1.75e-1)" "unprognostic (2.30e-2)" "unprognostic (8.30e-2)" "unprognostic (4.25e-2)" "unprognostic (2.98e-1)" "unprognostic (2.32e-1)" "unprognostic (6.07e-3)" "unprognostic (2.81e-1)" 7.8 9.0 17.1 3.1 21.1 2.6 7.5 18.6 18.3 10.7 17.9 10.5 1.3 12.0 4.1 5.1 9.5 3.4 62.4 15.2 16.7 6.8 4.2 6.8 1.8 19.0 19.7 8.5 3.7 6.6 6.4 7.3 18.6 9.1 1.4 3.0 6.8 7.4 88.9 6.8 4.2 6.3 15.9 4.4 5.5 4.1 18.0 1.5 13.3 41.1 1.0 9.5 7.5 27.1 8.3 11.4 10.1 7.9 11.1 10.4 10.6 14.6 8.1 7.8 6.9 7.1 1.9 0.3 7.1 14.3 5.6 8.9 7.5 7.0 3.1 8.4 13.8 1.1 8.1 10.6 19.4 0.4 3.0 11.9 13.6 8.7 12.5 19.5 8.0 1.5 6.6 0.4 8.0 13.8 0.9 2.7 7.4 2.4 11.9 1.3 5.5 0.4 5.6 8.5 1.6 9.3 7.8 6.7 17.9 5.5 9.0 0.2 16.0 10.2 5.1 14.8 9.4 1.7 0.9 0.2 10.4 0.0 6.5 0.4 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.5 0.4 1.1 0.3 0.3 0.3 0.2 0.2 17.1 21.1 18.6 18.3 15.2 16.7 19.0 19.7 18.6 15.9 18.0 27.1 13.0 38.5 11.7 32.3 0.7 4.6 5.1 3.4 6.2 14.1 4.6 14.7 9.8 4.3 7.2 11.0 6.2 9.1 0.7 0.2 1.9 2.2 1.8 6.3 18.0 8.5 0.0 0.0 28.8 2.2 6.2 9.4 1.1 7.4 1.3 18.9 9.7 1.6 5.7 23.5 16.4 1.3 0.0 1.3 2.4 1.6 15.5 3.3 5.4 18.7 0.9 21.4 0.0 13.6 64.9 2.2 0.5 8.2 0.3 5.1 0.1 2.6 4.1 6.4 6.6 14.4 9.9 0.9 2.9 2.3 3.8 9.3 2.0 21.5 0.7 3.3 RLBP1 CRALBP ENSG00000140522 "Retinaldehyde binding protein 1" P12271 15 89209869-89221614 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Transport, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "retina: 265.6" "Cell type enriched" "Detected in some" 34 "Muller glia cells: 3148.2" "Group enriched" "Detected in some" 30 "glioma: 3.7;melanoma: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 53 "SK-MEL-30: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042051, HPA044083" Enhanced Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Nucleoplasm, Centrosome" "HPA042051: AB_2732495, HPA044083: AB_2678802" "unprognostic (3.19e-2)" "unprognostic (2.66e-1)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (8.68e-2)" "unprognostic (1.76e-1)" "unprognostic (8.24e-3)" "unprognostic (5.21e-2)" "unprognostic (3.17e-1)" "unprognostic (2.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.78e-1)" "unprognostic (1.13e-1)" "unprognostic (8.42e-2)" 0.0 0.2 14.9 0.1 16.9 0.1 0.0 15.0 20.8 0.0 16.7 1.6 0.2 0.0 0.2 0.0 0.0 0.0 0.0 15.7 14.5 0.0 0.0 0.0 0.0 14.5 14.2 0.0 0.0 0.0 2.6 0.0 14.3 0.0 0.1 265.6 0.0 0.0 0.1 0.0 0.4 0.1 14.0 0.0 0.2 0.9 14.9 0.0 0.0 0.1 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.9 16.9 15.0 20.8 15.7 14.5 14.5 14.2 14.3 14.0 14.9 14.9 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.3 0.0 0.0 0.0 39.6 4.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.5 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 2.0 3148.2 0.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.9 0.0 0.0 0.0 0.2 0.2 0.0 0.0 20.0 0.0 0.0 0.0 0.0 RNF13 RZF ENSG00000082996 "Ring finger protein 13" O43567 3 149812770-149962139 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 591.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 462.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064784 Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" Cytosol "HPA064784: AB_2685350" "unprognostic (1.27e-1)" "unprognostic (2.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.93e-2)" "unprognostic (1.80e-1)" "unprognostic (9.64e-2)" "unprognostic (8.49e-2)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (1.25e-1)" "unprognostic (6.94e-3)" "unprognostic (1.13e-1)" "prognostic favorable (2.00e-8)" "unprognostic (2.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.17e-1)" "unprognostic (1.79e-1)" 48.2 41.2 58.1 40.4 95.2 19.9 53.9 88.1 91.5 33.6 63.7 35.0 28.9 33.3 57.2 32.6 30.2 40.6 34.4 55.0 77.3 67.9 73.8 64.1 38.0 101.8 83.9 35.6 36.1 52.3 18.3 64.1 100.8 46.6 37.1 40.4 75.5 39.3 36.5 32.5 30.5 36.9 85.6 53.0 34.3 25.2 75.9 32.0 64.0 42.6 33.2 42.3 28.9 131.0 60.6 39.4 24.4 29.0 92.2 55.2 40.3 32.2 86.2 32.3 47.4 33.4 84.4 26.6 48.7 42.0 58.7 58.0 37.5 41.5 42.9 34.1 24.6 35.8 17.3 31.2 61.5 35.0 41.8 59.9 73.1 26.5 71.8 37.3 37.0 24.9 10.1 49.7 28.0 34.5 26.2 18.8 16.8 58.6 29.1 19.0 26.7 108.5 54.2 29.6 12.6 37.6 28.5 39.9 110.3 19.2 79.2 34.0 37.8 40.8 16.5 45.6 23.4 89.9 61.9 51.5 35.9 30.1 23.6 98.2 130.1 106.5 37.4 153.8 48.8 51.9 41.5 44.8 93.1 48.4 38.0 42.4 462.3 46.3 207.8 68.3 48.7 104.5 58.1 95.2 88.1 91.5 55.0 77.3 101.8 83.9 100.8 85.6 75.9 131.0 100.9 109.0 72.3 78.7 55.3 73.5 68.2 84.3 74.0 44.5 54.5 51.1 27.3 48.6 68.1 47.8 29.2 101.2 61.9 30.2 43.0 63.0 2.5 32.5 34.5 69.4 20.3 32.4 122.1 70.6 83.5 84.8 31.6 39.7 60.8 14.6 80.3 53.7 201.2 21.9 98.8 27.7 67.1 183.9 173.7 6.7 76.1 177.6 103.2 92.8 93.5 98.5 38.1 115.6 591.2 58.7 33.6 88.0 62.4 71.9 38.5 71.5 40.4 37.2 92.1 76.3 55.5 23.6 32.5 52.3 72.5 52.5 49.8 38.2 27.7 55.8 RNF14 "ARA54, HFB30, TRIAD2" ENSG00000013561 "Ring finger protein 14" Q9UBS8 5 141958328-141990292 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 257.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008716, HPA064746" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA008716: AB_1856337, HPA064746: " "unprognostic (7.45e-3)" "unprognostic (1.38e-1)" "unprognostic (8.56e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-2)" "unprognostic (7.24e-3)" "unprognostic (2.35e-1)" "unprognostic (4.05e-2)" "unprognostic (5.22e-2)" "unprognostic (7.42e-2)" "unprognostic (7.92e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.71e-4)" "unprognostic (6.89e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.06e-2)" 48.4 51.8 31.5 26.0 32.7 20.2 45.6 32.7 42.8 36.6 30.6 40.7 33.2 33.6 43.2 32.6 29.7 32.6 71.2 33.3 35.6 65.3 67.6 30.2 32.3 35.3 38.2 32.3 37.2 104.0 23.7 39.8 36.3 44.0 41.2 40.4 37.1 40.2 66.7 23.5 36.4 43.3 33.4 28.9 35.4 74.5 36.5 36.7 55.1 85.8 33.7 32.1 23.4 33.7 38.3 62.5 43.1 85.1 75.7 78.8 29.0 76.8 42.6 52.8 58.1 52.4 43.4 67.1 87.5 79.3 79.4 20.6 55.6 75.4 47.0 51.1 48.5 42.9 30.2 24.0 83.2 47.7 36.9 59.7 64.9 70.3 87.6 45.6 66.2 46.0 53.0 91.7 109.4 45.7 46.6 15.3 18.3 46.2 71.0 30.2 47.8 73.8 71.7 65.2 47.5 38.3 67.3 121.3 133.2 47.8 85.0 36.7 69.3 69.6 22.6 33.2 74.0 56.8 72.1 61.8 59.7 57.4 87.9 79.6 22.0 23.2 26.9 26.9 26.0 19.5 23.2 26.9 27.4 18.1 17.6 25.9 5.5 30.1 33.9 28.9 29.1 19.7 31.5 32.7 32.7 42.8 33.3 35.6 35.3 38.2 36.3 33.4 36.5 33.7 18.1 9.6 19.3 12.7 12.5 10.7 15.9 19.6 11.4 20.2 18.4 15.0 45.4 11.5 18.1 22.0 16.7 29.1 13.3 22.9 68.4 29.2 257.1 14.1 20.8 21.7 15.0 59.1 25.1 24.9 26.1 18.2 18.3 16.4 22.2 32.0 20.7 33.1 24.5 23.5 22.9 14.9 24.4 29.7 10.4 39.3 19.3 17.1 32.0 13.1 14.8 28.7 29.9 15.6 18.6 26.3 14.0 33.4 13.5 19.2 28.3 50.5 15.8 16.3 39.5 15.8 23.0 38.7 25.8 15.6 10.5 60.5 16.4 25.0 15.0 15.0 RNF170 "ADSA, DKFZP564A022, SNAX1" ENSG00000120925 "Ring finger protein 170" Q96K19 8 42849637-42897290 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050931, HPA054621" Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "HPA050931: AB_2681279, HPA054621: AB_2682545" "unprognostic (3.06e-2)" "unprognostic (4.20e-1)" "unprognostic (9.54e-2)" "unprognostic (6.37e-2)" "unprognostic (4.59e-2)" "unprognostic (2.84e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.59e-1)" "unprognostic (3.03e-2)" "unprognostic (1.61e-3)" "unprognostic (4.13e-3)" "unprognostic (2.00e-1)" "unprognostic (1.49e-1)" "unprognostic (2.13e-1)" 9.3 11.7 14.5 7.5 15.6 2.4 12.7 16.3 16.8 7.9 11.5 11.1 10.3 9.5 14.9 14.2 9.3 9.2 7.7 14.1 15.8 16.4 19.7 9.3 9.4 15.9 15.5 12.3 8.1 13.5 9.5 19.2 16.2 11.0 11.3 35.6 11.0 10.6 11.9 15.1 11.4 7.6 15.0 9.1 10.7 5.9 15.6 6.1 28.8 9.2 9.9 7.6 8.5 18.3 11.4 18.1 18.2 9.2 29.4 29.7 10.8 13.3 18.1 12.3 13.2 8.5 36.0 13.6 15.7 12.8 22.1 9.6 9.6 13.2 10.8 9.4 10.4 15.9 8.5 9.3 16.1 2.0 10.9 26.0 20.4 9.3 18.8 16.0 13.3 15.0 14.6 15.8 19.9 3.4 17.0 9.5 8.6 24.1 6.5 8.7 24.2 7.7 19.6 10.8 4.7 14.3 12.8 8.9 23.0 17.7 23.1 9.5 19.5 13.2 5.8 17.8 4.3 25.2 26.4 15.7 18.2 6.7 13.6 1.4 5.7 2.1 2.9 5.7 4.2 6.6 4.8 5.3 8.8 3.9 5.6 4.1 0.6 4.9 5.5 8.9 6.7 4.5 14.5 15.6 16.3 16.8 14.1 15.8 15.9 15.5 16.2 15.0 15.6 18.3 13.5 48.1 20.5 41.1 16.1 7.6 13.1 22.3 5.7 44.8 14.9 9.5 11.5 15.7 29.2 23.9 89.6 41.6 9.8 22.1 17.6 21.6 1.7 16.0 14.5 15.2 13.1 5.5 36.7 27.8 19.4 20.0 11.2 13.3 9.5 25.5 21.8 21.7 22.9 21.9 43.7 15.3 20.3 18.5 9.2 2.4 15.2 15.4 8.8 15.9 21.9 31.8 30.9 36.2 75.9 32.2 18.4 20.7 10.7 9.6 34.5 22.1 33.3 72.1 13.1 23.9 12.1 14.9 19.3 12.5 11.5 31.2 12.8 25.7 16.6 12.2 ROPN1 "CT91, ODF6, ROPN1A, ropporin" ENSG00000065371 "Rhophilin associated tail protein 1" Q9HAT0 3 123968521-123992178 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 158.8" "Group enriched" "Detected in some" 9 "Early spermatids: 1370.6;Late spermatids: 629.0;Spermatocytes: 355.0" "Cancer enriched" "Detected in some" 4 "melanoma: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "SK-MEL-30: 28.7" "Low region specificity" "Detected in single" HPA052530 Supported NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA052530: AB_2681861" "unprognostic (1.75e-5)" "unprognostic (2.24e-1)" "unprognostic (4.77e-2)" "unprognostic (7.66e-2)" "unprognostic (1.72e-1)" "unprognostic (1.95e-2)" "unprognostic (3.13e-1)" "unprognostic (2.08e-2)" "unprognostic (8.35e-4)" 0.0 0.0 0.3 0.0 0.2 0.0 20.5 0.1 0.2 0.0 0.0 0.5 0.0 0.0 3.6 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.5 0.3 6.1 0.0 0.1 1.6 0.1 0.0 0.0 0.0 0.0 158.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 28.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.1 0.4 0.6 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.0 49.4 81.7 7.8 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 1370.6 0.2 0.0 1.4 2.4 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 629.0 8.7 1.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 355.0 5.7 0.0 0.0 0.0 0.4 0.0 0.5 0.0 ROPN1B ENSG00000114547 "Rhophilin associated tail protein 1B" Q9BZX4 3 125969160-125983454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 214.2" "Group enriched" "Detected in many" 4 "Early spermatids: 2012.7;Late spermatids: 1967.9" "Group enriched" "Detected in some" 5 "breast cancer: 1.3;melanoma: 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SK-MEL-30: 54.6;WM-115: 18.5" HPA052530 Supported NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 34: Spermatids - Unknown function" "HPA052530: AB_2681861" "unprognostic (7.73e-3)" "unprognostic (1.35e-2)" "unprognostic (2.22e-3)" "unprognostic (2.76e-2)" "unprognostic (7.19e-2)" "unprognostic (3.39e-2)" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (8.15e-2)" "unprognostic (1.96e-2)" "unprognostic (1.09e-2)" "unprognostic (8.18e-2)" "unprognostic (5.91e-2)" "unprognostic (5.01e-2)" "unprognostic (1.74e-2)" "unprognostic (6.89e-3)" "unprognostic (3.78e-2)" 0.3 0.5 1.3 0.2 1.6 0.1 38.2 2.0 1.8 0.2 0.0 0.1 0.1 0.3 22.1 0.1 0.5 0.0 3.0 1.3 1.2 0.3 1.2 0.3 0.6 0.8 1.3 0.3 0.3 0.0 3.0 0.2 0.9 0.7 0.0 1.8 14.6 0.2 0.4 7.0 0.1 0.0 0.5 0.1 0.1 214.2 0.9 0.0 0.7 0.8 0.3 0.4 0.1 2.0 0.0 0.0 0.3 0.2 0.0 0.0 2.9 0.0 0.3 0.2 0.2 0.2 2.4 1.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 1.4 0.0 0.1 1.1 0.2 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.3 0.9 0.3 0.1 0.0 54.6 0.1 0.7 0.7 0.0 0.0 0.5 0.2 0.2 5.4 1.1 0.3 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 1.6 2.0 1.8 1.3 1.2 0.8 1.3 0.9 0.5 0.9 2.0 0.6 0.0 0.0 1.3 0.3 3.7 0.1 1.4 0.0 0.2 60.1 86.2 18.8 0.0 3.9 0.0 0.0 0.3 2.0 0.0 0.0 0.2 2012.7 3.1 0.1 1.6 0.0 0.0 0.5 0.2 2.5 1.3 0.0 0.1 0.0 0.2 0.0 0.5 0.1 3.3 0.4 0.0 2.0 0.0 2.0 1967.9 19.0 1.5 149.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 9.8 0.0 0.6 0.0 0.1 17.8 0.2 19.7 0.0 1.0 493.4 11.8 0.0 0.6 0.1 0.5 0.0 0.0 1.2 RPLP1 LP1 ENSG00000137818 "Ribosomal protein lateral stalk subunit P1" P05386 15 69452814-69456205 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 28402.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003368 Supported "Endoplasmic reticulum,Cytosol" NA NA 2000000 "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA003368: AB_1079845" "unprognostic (5.04e-3)" "unprognostic (2.26e-2)" "unprognostic (2.02e-2)" "unprognostic (4.29e-2)" "unprognostic (6.32e-2)" "unprognostic (1.35e-1)" "unprognostic (4.36e-2)" "unprognostic (2.92e-1)" "unprognostic (1.30e-1)" "unprognostic (2.36e-1)" "unprognostic (2.79e-1)" "unprognostic (9.55e-2)" "prognostic unfavorable (2.30e-9)" "unprognostic (7.75e-2)" "unprognostic (1.57e-1)" "unprognostic (2.59e-1)" "unprognostic (5.83e-2)" 1779.5 1664.6 852.0 893.4 872.7 2781.2 1895.2 821.7 1109.7 2465.3 920.5 2035.4 1200.3 1805.3 349.4 2773.4 1670.9 579.0 2121.7 813.6 844.4 1703.1 1566.2 1439.7 1583.3 871.6 857.5 3354.5 2003.6 264.6 924.6 565.5 866.0 1991.6 449.1 157.6 1705.8 417.0 4746.4 4498.6 1693.4 529.7 892.5 1992.0 2147.0 492.5 873.6 643.5 1140.9 761.4 1017.9 2099.9 2372.6 891.4 1890.5 1882.4 827.9 1919.4 1172.4 1394.2 1770.4 1615.7 960.9 892.0 711.8 1918.7 1861.9 2622.2 2346.4 869.5 811.2 2521.6 1296.6 1287.5 193.1 2639.9 3956.6 2208.5 2153.1 1914.5 2045.2 1976.4 1931.2 1782.1 2199.9 653.6 1219.6 1438.9 1092.7 2265.9 2127.7 2160.7 642.2 1757.0 2163.4 5781.3 3098.7 1172.2 1802.9 2192.5 2696.6 3893.7 876.0 2002.9 1319.3 2558.5 1620.5 1978.2 6979.8 742.8 1633.9 4449.5 1915.7 1273.2 2851.6 1535.0 2672.3 4382.2 7690.0 2245.6 1524.1 4968.6 1076.9 2903.3 5350.5 1819.3 3182.4 3677.4 5811.2 9096.0 6532.4 4349.4 6100.6 7551.7 6871.8 6057.1 733.9 5147.0 2138.6 6392.6 5921.8 13416.9 852.0 872.7 821.7 1109.7 813.6 844.4 871.6 857.5 866.0 892.5 873.6 891.4 3508.0 1891.0 3795.4 16.0 11229.3 24186.3 18565.6 9896.5 18630.1 626.6 14197.1 19613.8 1854.3 3877.6 5293.4 2265.9 350.3 9217.3 6668.2 2484.5 5141.7 5608.7 475.1 2702.4 5765.4 5131.7 2926.5 6423.8 19.7 7158.4 12076.7 5235.1 3541.4 4232.4 2605.7 4287.7 5261.2 6536.1 8166.9 373.5 22.5 7238.9 2396.6 8309.7 12226.0 1764.3 8447.2 6779.7 9051.8 28.1 11829.2 4015.4 6451.2 15.6 42.8 7495.3 5127.5 4732.9 10308.0 16198.4 5565.3 8039.9 2204.8 1167.3 2530.9 5356.8 5872.6 690.3 1864.1 18779.3 28402.5 9502.3 9179.6 6940.6 8549.1 17342.5 RPP25 FLJ20374 ENSG00000178718 "Ribonuclease P and MRP subunit p25" Q9BUL9 15 74954418-74956772 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 95.1;Hofbauer cells: 77.0;Rod photoreceptor cells: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 25.8" "Group enriched" "Detected in many" 5 "dendritic cells: 25.8;monocytes: 10.1" "Cell line enhanced" "Detected in many" "HHSteC: 46.0;SCLC-21H: 42.9;SK-MEL-30: 67.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "olfactory bulb: 23.0" HPA046900 Approved Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Centriolar satellite" "HPA046900: AB_10962049" "unprognostic (9.36e-2)" "unprognostic (7.17e-3)" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (7.18e-2)" "unprognostic (5.73e-3)" "unprognostic (5.50e-3)" "unprognostic (7.78e-2)" "unprognostic (1.44e-1)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (4.71e-3)" "unprognostic (5.50e-3)" "unprognostic (5.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.53e-1)" 6.0 13.2 7.4 2.7 8.9 0.4 4.5 14.6 8.5 7.1 6.5 7.9 7.2 3.7 1.8 6.9 4.4 4.5 5.5 4.9 10.8 5.1 3.1 5.8 3.9 16.5 12.7 15.4 7.6 23.0 5.2 7.2 16.4 4.2 4.8 12.8 4.6 1.7 1.4 4.9 5.7 2.5 10.8 10.8 7.1 3.0 12.8 2.4 8.9 1.5 3.4 7.7 5.4 12.7 23.6 17.5 4.4 0.1 1.5 0.9 7.4 4.3 5.2 1.3 1.2 24.1 21.0 0.0 19.4 4.4 1.2 6.9 13.7 0.8 0.3 8.9 0.7 0.1 19.9 0.5 46.0 0.0 13.3 5.9 0.6 8.5 0.0 0.9 20.4 5.5 16.1 0.0 4.6 9.1 3.8 6.3 20.8 40.9 7.0 0.1 0.0 15.8 4.2 0.4 42.9 32.1 32.6 28.8 67.4 2.2 5.7 18.7 4.6 0.0 1.4 3.8 0.2 0.4 0.1 0.1 2.3 36.6 25.1 0.0 5.2 0.0 2.3 10.1 1.3 3.4 1.5 1.8 5.1 3.7 3.8 3.0 0.4 0.5 7.7 25.8 0.7 2.5 7.4 8.9 14.6 8.5 4.9 10.8 16.5 12.7 16.4 10.8 12.8 12.7 5.3 3.2 1.1 0.3 4.9 11.0 7.5 9.1 11.4 95.1 11.8 9.9 1.6 14.3 6.4 9.2 4.2 2.3 17.0 24.4 13.7 13.7 0.3 1.6 4.7 8.9 10.2 0.8 0.7 19.3 4.3 23.9 14.8 3.6 0.0 3.4 31.8 1.6 77.0 21.9 10.0 12.5 14.2 14.8 8.6 2.6 39.4 9.3 14.2 1.0 16.1 13.4 4.1 0.0 6.3 13.8 20.5 30.1 8.2 19.1 27.5 16.6 1.3 72.3 13.1 4.3 10.4 1.4 6.5 18.2 11.5 2.3 2.1 26.6 20.7 10.5 RPS27AP5 ENSG00000231767 "Ribosomal protein S27a pseudogene 5" 1 192716132-192716653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "ovarian cancer: 16.3" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "NB-4: 4.6;SK-MEL-30: 4.2;THP-1: 4.7" "HPA041344, HPA049132, HPA054087" Uncertain Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA041344: AB_2677422, HPA049132: AB_2680646, HPA054087: AB_2682373" "unprognostic (2.56e-1)" "unprognostic (1.02e-2)" "unprognostic (1.90e-2)" "unprognostic (8.64e-2)" "unprognostic (3.78e-1)" "unprognostic (5.09e-2)" "unprognostic (7.80e-3)" "prognostic favorable (5.72e-4)" "unprognostic (1.59e-1)" "prognostic unfavorable (6.48e-4)" "unprognostic (3.07e-2)" "unprognostic (6.43e-2)" "unprognostic (5.80e-2)" "unprognostic (7.99e-2)" "unprognostic (2.58e-2)" "unprognostic (2.10e-2)" "unprognostic (3.62e-2)" 0.2 0.3 0.2 0.8 0.2 0.7 0.5 0.2 0.6 0.2 0.2 0.2 0.8 0.5 0.0 0.2 0.2 0.1 0.2 0.3 0.2 0.3 0.1 0.1 1.1 0.2 0.3 0.7 0.0 0.0 0.2 0.3 0.2 0.0 0.3 1.0 0.1 1.1 0.1 0.5 0.0 0.2 0.5 0.3 0.1 0.3 0.0 0.1 0.0 0.3 0.0 0.3 1.0 0.4 0.2 0.6 0.3 0.0 2.5 0.1 0.5 0.0 0.3 0.0 0.7 0.2 2.5 0.0 0.2 1.0 0.1 0.3 0.0 0.9 0.5 0.4 0.4 1.9 0.2 0.7 1.3 0.3 0.4 0.2 0.0 0.1 0.2 0.2 0.1 0.7 0.0 0.5 0.9 4.6 1.1 0.1 0.2 1.0 0.3 0.6 0.3 1.3 0.8 1.6 0.2 1.5 4.2 0.1 1.0 4.7 0.5 0.6 1.2 0.8 2.4 1.5 1.1 0.9 0.8 0.7 0.1 1.2 0.9 0.5 2.0 1.3 2.8 4.2 3.5 2.2 1.8 3.8 4.4 4.5 0.3 3.0 1.0 1.6 2.5 5.6 0.2 0.2 0.2 0.6 0.3 0.2 0.2 0.3 0.3 0.2 0.3 0.3 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 RTP4 "IFRG28, Z3CXXC4" ENSG00000136514 "Receptor transporter protein 4" Q96DX8 3 187368385-187372076 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 33.2;Ductal cells: 46.4;Urothelial cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 10.9;GAMG: 14.2;HDLM-2: 12.3;Karpas-707: 9.7;REH: 9.9;SK-MEL-30: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064887, HPA071189" Uncertain Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA064887: AB_2685383, HPA071189: AB_2686357" "unprognostic (1.45e-2)" "unprognostic (2.46e-2)" "unprognostic (1.30e-1)" "unprognostic (1.44e-2)" "unprognostic (6.35e-2)" "unprognostic (3.24e-1)" "unprognostic (2.32e-1)" "unprognostic (3.78e-1)" "unprognostic (1.18e-1)" "unprognostic (6.87e-2)" "prognostic unfavorable (6.83e-4)" "unprognostic (1.34e-1)" "unprognostic (5.49e-2)" "unprognostic (3.44e-2)" "unprognostic (2.95e-2)" "prognostic favorable (4.35e-4)" "prognostic favorable (1.45e-4)" 2.1 2.7 2.4 5.1 2.5 1.1 6.0 2.3 3.0 4.8 2.0 5.9 9.1 4.3 3.2 1.9 10.8 6.2 3.2 2.1 2.4 4.4 6.1 7.0 8.1 3.1 2.4 4.0 2.5 0.6 1.1 2.2 2.8 4.0 6.0 0.2 10.7 5.2 1.0 2.4 8.2 4.5 3.5 8.5 8.1 1.0 2.5 9.2 1.9 2.3 5.8 8.2 2.7 2.7 3.1 0.0 0.0 0.0 1.4 4.9 0.1 0.0 1.2 2.0 1.8 0.0 10.9 1.4 0.0 1.3 14.2 3.6 0.0 0.1 0.0 12.3 0.0 0.0 0.0 0.1 1.8 0.0 2.7 1.2 0.0 0.4 0.0 0.4 0.4 0.3 0.0 9.7 0.0 0.0 7.3 0.0 0.0 0.0 0.0 9.9 0.0 8.0 2.6 7.9 0.0 0.0 0.0 0.2 19.7 0.1 0.0 4.9 0.2 0.1 0.2 0.0 0.1 7.8 2.6 0.1 0.0 2.7 6.0 7.0 8.3 5.9 11.5 10.2 11.5 6.2 9.1 10.5 7.1 5.3 6.9 8.2 2.3 14.9 13.2 0.2 19.8 6.7 2.4 2.5 2.3 3.0 2.1 2.4 3.1 2.4 2.8 3.5 2.5 2.7 7.4 6.4 4.5 0.3 4.3 1.7 33.2 10.5 1.8 0.0 4.0 5.5 0.7 11.5 11.3 5.5 0.0 0.1 4.2 6.0 15.6 46.4 0.0 13.6 4.3 9.6 9.1 0.4 0.0 9.8 0.5 4.2 10.7 6.1 1.3 1.6 10.8 4.5 5.5 0.0 0.1 9.6 6.1 7.8 2.5 0.0 2.1 6.4 1.8 1.9 8.9 3.7 25.7 1.0 0.7 16.9 9.4 4.9 2.0 12.9 17.9 3.1 24.6 0.1 0.0 1.3 3.0 0.1 0.1 1.3 1.3 0.3 8.3 12.0 7.8 52.6 RXRG NR2B3 ENSG00000143171 "Retinoid X receptor gamma" P48443 1 165400922-165445355 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.1;pituitary gland: 29.9;retina: 24.3;skeletal muscle: 49.7" "Group enriched" "Detected in some" 4 "Astrocytes: 13.4;Cone photoreceptor cells: 25.0;Melanocytes: 28.4;Muller glia cells: 16.8;Sertoli cells: 13.1;Skeletal myocytes: 35.9" "Group enriched" "Detected in many" 13 "melanoma: 25.7;thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SK-MEL-30: 39.4" "Region enriched" "Detected in many" 5 "basal ganglia: 100.2" "Low region specificity" "Detected in many" "CAB002615, HPA012933" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "CAB002615: , HPA012933: AB_2732406" "unprognostic (2.29e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.66e-1)" "unprognostic (4.29e-2)" "unprognostic (6.19e-2)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (9.13e-2)" "unprognostic (6.86e-2)" "unprognostic (2.95e-2)" "unprognostic (5.41e-3)" "unprognostic (2.52e-2)" "unprognostic (6.12e-3)" "unprognostic (1.18e-1)" "prognostic favorable (9.40e-5)" "unprognostic (5.03e-2)" 2.4 3.2 14.6 0.4 16.6 0.0 1.0 11.7 17.4 3.0 11.7 4.1 0.7 1.1 0.7 1.0 2.8 0.6 5.3 12.4 21.5 0.2 0.3 2.8 0.3 25.6 14.8 1.0 2.1 0.1 29.9 0.7 22.2 1.1 2.0 24.3 1.2 1.4 49.7 2.3 1.6 1.2 13.6 0.4 1.4 1.0 32.1 0.1 0.7 7.6 0.0 1.6 2.1 15.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.6 0.0 0.0 0.0 39.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 16.6 11.7 17.4 12.4 21.5 25.6 14.8 22.2 13.6 32.1 15.6 0.9 0.0 0.0 13.4 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 1.8 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.1 0.6 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.3 0.0 0.0 4.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.3 2.8 5.0 0.0 28.4 0.0 0.0 16.8 0.0 1.0 1.3 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.5 13.1 35.9 3.4 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 S100A1 "S100-alpha, S100A" ENSG00000160678 "S100 calcium binding protein A1" P23297 1 153627926-153632039 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 3076.8;skeletal muscle: 3060.2;tongue: 4911.5" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 1848.3" "Group enriched" "Detected in all" 5 "melanoma: 210.5;ovarian cancer: 110.1;thyroid cancer: 123.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Hep G2: 325.8;SK-MEL-30: 1130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002599, HPA006462" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 290000 "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Nucleoplasm, Golgi apparatus" "CAB002599: AB_2315307, HPA006462: AB_1079857" "unprognostic (6.13e-2)" "unprognostic (7.60e-2)" "unprognostic (5.96e-5)" "prognostic unfavorable (1.12e-4)" "unprognostic (1.19e-1)" "unprognostic (3.24e-2)" "unprognostic (2.36e-1)" "unprognostic (2.34e-3)" "unprognostic (6.83e-3)" "unprognostic (5.22e-1)" "unprognostic (5.04e-3)" "unprognostic (9.62e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.68e-1)" "unprognostic (4.56e-2)" "unprognostic (2.70e-3)" "unprognostic (9.74e-4)" 179.7 8.3 811.3 6.5 898.6 2.3 77.2 851.4 952.4 2.9 643.9 14.5 11.1 4.2 1.0 81.0 41.8 4.9 3076.8 779.4 813.6 194.9 4.5 3.9 5.1 907.6 894.8 2.0 16.8 160.9 54.6 18.1 871.2 29.0 1.2 36.5 622.1 9.3 3060.2 23.0 6.9 1.6 847.7 4.2 23.1 5.9 882.9 9.4 167.9 4911.5 4.0 4.3 2.9 967.6 6.0 3.4 3.9 33.7 0.5 0.2 2.9 7.7 0.2 0.6 0.2 6.6 3.4 3.7 137.7 0.6 2.7 10.3 0.3 0.4 0.0 4.2 3.3 8.2 5.4 325.8 0.4 3.0 2.3 0.7 0.0 0.0 0.1 7.9 0.0 1.5 27.2 3.7 0.1 10.6 1.2 4.9 1.8 4.3 2.6 22.5 3.3 8.0 6.0 12.1 6.1 1.9 3.5 10.6 1130.2 11.1 32.8 16.2 2.7 3.3 2.8 3.0 3.8 6.1 5.7 6.2 2.5 6.2 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 811.3 898.6 851.4 952.4 779.4 813.6 907.6 894.8 871.2 847.7 882.9 967.6 4.3 0.0 0.0 59.4 9.5 9.7 1.2 0.4 1.8 1.1 369.9 354.1 74.4 8.6 0.2 154.5 2.1 1.1 5.9 1.1 162.4 0.9 0.6 90.5 17.3 5.3 1.8 0.0 0.3 3.7 1.9 6.0 0.0 193.3 0.0 0.0 7.9 4.7 199.1 0.0 0.3 3.7 0.0 0.6 3.5 2.2 6.5 15.6 341.5 2.8 0.0 163.5 0.0 2.0 45.8 1.9 0.6 9.1 0.0 1.8 0.9 1848.3 0.2 2.7 0.0 67.0 4.2 3.8 2.8 1.0 2.3 3.4 8.2 2.3 1.8 0.7 SAP30L "FLJ11526, NS4ATP2" ENSG00000164576 "SAP30 like" Q9HAJ7 5 154445997-154461053 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048665, HPA078308" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "HPA048665: AB_2680486, HPA078308: " "unprognostic (3.79e-3)" "unprognostic (1.44e-2)" "unprognostic (1.25e-1)" "unprognostic (7.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.09e-4)" "unprognostic (1.33e-1)" "unprognostic (1.61e-1)" "unprognostic (1.32e-1)" "unprognostic (4.33e-2)" "prognostic favorable (2.06e-5)" "unprognostic (3.36e-1)" "prognostic favorable (1.71e-4)" "unprognostic (1.62e-2)" "unprognostic (3.34e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.69e-4)" 10.0 8.4 12.2 5.3 13.7 1.6 11.3 13.0 13.2 14.0 10.2 14.9 10.5 13.4 9.0 7.1 12.9 6.7 9.8 11.1 12.9 13.1 8.0 9.3 6.8 13.2 13.4 19.7 6.4 13.8 5.0 7.7 12.7 10.6 8.7 6.1 7.3 12.4 14.1 11.4 11.0 11.6 13.7 8.9 8.9 7.7 13.1 9.9 9.3 15.3 8.3 10.9 10.0 13.8 9.0 7.3 13.3 8.8 28.4 22.5 6.5 9.2 19.9 10.4 11.2 4.9 5.0 9.7 7.2 14.0 12.1 7.1 10.1 7.5 11.6 4.9 9.9 7.9 6.8 3.6 8.5 10.5 5.7 8.2 13.4 4.6 11.3 16.0 8.5 9.1 3.3 6.0 8.8 4.5 9.9 6.7 3.3 8.2 5.0 9.4 13.3 4.8 6.0 4.4 8.0 10.5 7.3 15.6 17.6 12.4 5.6 12.8 12.1 7.2 5.3 9.6 6.6 5.6 8.6 5.0 10.6 8.1 4.2 0.0 0.3 0.3 0.5 0.4 0.6 0.2 0.6 0.6 0.3 0.5 0.6 0.4 0.2 1.4 1.2 0.4 0.6 0.3 12.2 13.7 13.0 13.2 11.1 12.9 13.2 13.4 12.7 13.7 13.1 13.8 25.7 19.2 6.9 7.8 7.1 17.3 8.7 4.2 8.0 4.5 17.0 14.1 19.8 17.2 6.3 3.7 6.2 7.7 15.5 26.5 3.9 4.8 22.4 15.6 18.4 17.6 7.2 11.0 6.6 8.2 12.3 18.1 4.6 9.8 1.3 16.4 15.7 16.3 8.5 10.1 6.5 11.4 0.0 9.7 12.4 18.0 20.5 11.3 10.6 9.4 10.7 21.4 14.4 6.0 12.1 10.6 13.9 18.0 7.8 16.9 32.7 10.5 9.5 5.8 0.0 14.9 16.0 16.1 17.2 5.5 18.2 6.3 8.9 10.5 12.1 13.3 SDCBP "MDA-9, SYCL" ENSG00000137575 "Syndecan binding protein" O00560 8 58552924-58582859 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 959.8;Melanocytes: 889.4" "Cancer enriched" "Detected in all" 4 "melanoma: 244.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1908.0" "Group enriched" "Detected in all" 5 "granulocytes: 1908.0;monocytes: 562.9" "Cell line enhanced" "Detected in many" "HHSteC: 787.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012245, HPA023840" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA 1300000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Nuclear membrane" "CAB012245: , HPA023840: AB_1857712" "unprognostic (2.39e-2)" "unprognostic (3.34e-2)" "unprognostic (1.84e-2)" "unprognostic (4.45e-2)" "unprognostic (9.15e-2)" "unprognostic (2.60e-3)" "unprognostic (7.14e-2)" "unprognostic (1.04e-3)" "unprognostic (1.11e-1)" "unprognostic (5.68e-2)" "unprognostic (3.05e-2)" "unprognostic (3.01e-1)" "unprognostic (1.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.02e-2)" "unprognostic (2.82e-2)" "unprognostic (2.92e-1)" 228.5 126.4 94.1 160.8 111.8 245.6 167.1 102.0 130.1 160.9 112.2 119.6 83.1 109.8 83.6 88.8 95.7 194.8 120.6 103.7 112.6 126.6 174.0 223.9 121.2 113.7 103.8 89.1 80.8 132.9 45.8 264.3 113.5 70.8 134.7 26.8 124.9 78.3 65.9 84.8 92.8 151.2 107.4 203.0 130.0 41.1 110.8 129.9 120.7 113.7 92.8 248.8 91.9 123.7 123.5 185.9 194.2 101.4 711.7 607.1 86.1 122.9 439.6 175.3 228.9 74.8 250.7 0.4 194.8 166.4 321.2 49.7 106.0 142.4 215.7 22.6 91.3 184.3 156.0 60.6 787.9 47.7 287.1 417.9 188.1 176.5 525.2 273.0 428.0 125.2 92.3 104.6 403.4 32.4 104.1 55.9 122.2 478.6 52.3 49.6 59.4 24.3 282.1 127.0 84.9 153.5 133.8 56.1 630.0 213.8 51.0 127.9 382.3 168.8 72.5 200.8 81.5 31.4 45.6 74.8 428.9 0.5 155.1 777.4 562.9 528.1 61.2 349.6 78.0 69.4 82.0 67.3 251.8 61.0 103.9 80.2 1908.0 42.6 329.1 69.9 103.0 453.2 94.1 111.8 102.0 130.1 103.7 112.6 113.7 103.8 113.5 107.4 110.8 123.7 382.7 211.5 115.9 26.8 170.3 338.7 321.2 312.5 108.1 10.8 86.7 54.6 70.6 88.6 181.3 206.0 16.7 284.3 220.2 192.9 225.0 392.9 7.8 110.9 87.0 412.7 112.3 116.6 18.5 291.6 756.8 308.1 162.1 120.5 396.9 62.9 378.3 101.9 782.5 15.2 23.7 180.3 248.2 552.1 959.8 15.9 233.9 626.0 889.4 71.2 312.4 94.3 51.5 21.6 16.3 297.9 152.9 159.9 65.1 307.4 78.4 211.2 169.8 11.1 98.6 82.7 177.4 14.8 8.4 73.3 173.2 483.0 256.2 117.0 129.2 457.6 SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716460 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047533 Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear membrane" "Golgi apparatus" "HPA047533: AB_2680078" "unprognostic (8.81e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "prognostic favorable (1.94e-5)" "unprognostic (3.39e-2)" "prognostic unfavorable (5.99e-5)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-2)" "unprognostic (6.17e-2)" "unprognostic (6.24e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "prognostic favorable (2.95e-4)" "unprognostic (7.89e-2)" 142.9 138.1 66.2 83.4 69.4 172.2 136.2 69.0 80.4 147.1 76.6 110.8 82.9 111.0 202.5 81.6 103.6 97.5 98.4 63.7 72.6 137.2 152.3 107.9 112.6 74.1 67.2 168.6 139.4 114.6 84.5 115.1 73.9 82.0 124.9 37.0 95.9 87.5 154.3 70.5 86.4 96.3 72.4 86.2 95.3 61.5 69.4 93.2 177.5 147.4 98.2 137.3 94.0 75.3 201.7 320.7 286.7 425.4 368.5 462.8 225.4 310.1 356.5 241.9 291.2 347.1 443.0 99.0 198.8 370.3 277.2 408.3 409.1 243.4 255.5 267.1 239.4 279.4 358.8 324.9 311.7 213.4 281.2 315.8 305.0 169.1 285.1 366.0 337.9 116.7 295.8 244.3 315.1 363.1 89.2 345.8 282.1 266.2 135.4 101.6 368.4 302.9 472.6 424.4 131.2 300.8 257.3 239.5 598.5 407.0 248.5 416.6 254.3 240.0 181.0 209.8 361.9 224.4 509.6 150.0 226.4 331.7 180.6 83.5 161.1 89.7 95.1 173.7 95.0 101.0 114.8 104.7 165.8 90.0 95.1 98.0 111.6 134.3 184.8 160.9 168.8 200.8 66.2 69.4 69.0 80.4 63.7 72.6 74.1 67.2 73.9 72.4 69.4 75.3 261.1 89.8 99.1 25.8 131.8 107.1 179.4 356.6 90.5 30.0 163.7 202.6 68.2 228.8 188.0 128.8 22.9 309.1 171.9 111.1 238.7 258.8 46.3 118.5 268.0 217.2 157.4 101.7 21.2 247.3 655.3 206.0 120.8 184.1 218.4 191.0 197.7 165.5 363.3 20.2 22.8 218.7 168.9 386.7 337.2 100.6 299.5 337.3 158.3 24.4 396.7 110.5 204.9 26.7 38.3 183.4 136.3 166.3 197.9 185.7 142.7 350.9 99.3 38.2 170.9 173.5 225.5 233.5 169.6 135.2 119.9 305.8 153.4 237.6 210.7 242.2 SELENOF SEP15 ENSG00000183291 "Selenoprotein F" O60613 1 86862445-86914424 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 248.6;Ductal cells: 235.9;Extravillous trophoblasts: 338.3;Hofbauer cells: 241.2;Syncytiotrophoblasts: 315.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054937 Approved Nucleoli,Cytosol "Intracellular and membrane" No No 420000 "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoli Cytosol "HPA054937: AB_2682642" "unprognostic (6.15e-2)" "unprognostic (6.98e-3)" "prognostic favorable (6.53e-4)" "unprognostic (6.20e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (8.17e-4)" "prognostic unfavorable (1.98e-5)" "unprognostic (1.65e-1)" "unprognostic (6.51e-3)" "unprognostic (3.38e-2)" "unprognostic (3.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.79e-3)" "unprognostic (2.39e-2)" "unprognostic (1.09e-1)" "unprognostic (8.24e-3)" "unprognostic (1.34e-2)" 118.1 137.9 77.6 118.8 80.0 107.9 147.4 80.9 106.1 156.6 97.9 127.8 113.5 117.4 211.4 83.6 130.1 123.3 84.6 75.2 84.3 160.3 173.9 114.9 140.6 82.6 79.8 124.6 93.4 115.7 88.4 155.8 84.0 121.1 134.2 90.7 104.1 116.4 45.6 66.3 111.3 107.1 86.4 107.2 116.8 66.7 79.0 135.5 234.0 64.7 126.9 146.6 72.6 92.5 203.1 133.3 118.0 129.1 383.0 396.4 178.3 249.1 317.3 251.4 254.8 176.8 261.8 245.2 309.7 248.9 195.7 131.8 135.2 150.7 296.0 222.1 180.2 252.4 108.5 178.2 245.2 336.8 166.1 272.3 233.0 152.8 253.0 180.2 220.2 207.8 241.4 262.3 253.3 90.2 254.4 227.3 170.7 211.2 197.9 207.7 205.1 251.9 355.5 198.5 149.5 122.6 241.6 235.6 349.2 104.7 104.0 298.5 205.3 180.0 122.9 347.6 277.0 155.1 158.7 251.9 107.7 268.4 216.7 170.9 111.3 113.4 89.7 115.9 116.1 161.4 98.7 97.2 107.1 194.2 98.8 102.3 109.3 82.3 132.4 166.3 115.2 171.3 77.6 80.0 80.9 106.1 75.2 84.3 82.6 79.8 84.0 86.4 79.0 92.5 131.6 118.6 155.2 0.0 52.4 0.0 0.0 0.0 0.0 0.0 142.1 107.7 0.0 0.0 74.9 108.5 0.0 248.6 89.3 0.0 74.3 235.9 0.0 102.2 119.1 73.2 0.0 0.0 0.0 193.5 338.3 85.2 0.0 98.1 64.3 68.8 0.0 0.0 241.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 78.1 0.0 0.0 64.1 0.0 0.0 0.0 0.0 197.8 0.0 0.0 19.1 0.0 0.0 151.5 70.0 0.0 0.0 0.0 61.5 0.0 0.0 0.0 0.0 315.2 53.9 122.2 0.0 0.0 SEPTIN4 "ARTS, C17orf47, CE5B3, FLJ40121, H5, hCDCREL-2, hucep-7, MART, PNUTL2, SEPT4" ENSG00000108387 "Septin 4" "O43236, Q8NEP4" 17 58520250-58544368 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 1288.2;choroid plexus: 593.0;retina: 404.5" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 52.0;Smooth muscle cells: 38.9" "Cancer enhanced" "Detected in all" "glioma: 8.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 14.0;hTERT-RPE1: 19.4;SK-MEL-30: 32.8" "CAB006855, HPA021587, HPA022905, HPA028424" Enhanced Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "CAB006855: , HPA021587: AB_1856686, HPA022905: AB_1856687, HPA028424: AB_10601690" "unprognostic (1.12e-1)" "unprognostic (5.54e-2)" "unprognostic (8.36e-3)" "unprognostic (8.01e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-2)" "unprognostic (6.88e-3)" "unprognostic (2.73e-2)" "unprognostic (2.76e-1)" "unprognostic (8.02e-2)" "unprognostic (1.97e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (6.40e-3)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (8.75e-3)" 46.6 165.0 832.1 5.0 1011.1 0.5 33.5 861.9 1288.2 13.9 593.0 15.3 4.9 12.4 6.9 5.9 14.2 17.1 56.3 774.4 799.2 31.8 56.6 39.6 14.4 864.7 904.6 15.8 8.7 9.4 23.1 20.9 859.8 8.6 5.3 404.5 9.2 6.5 10.8 11.1 12.1 11.7 798.0 49.5 11.5 25.7 925.2 4.4 23.2 13.7 7.3 12.2 12.1 1080.0 0.0 0.6 1.2 3.6 1.4 0.2 0.6 0.2 0.5 2.1 2.4 0.2 0.5 0.0 5.1 0.8 3.2 0.4 1.8 1.4 0.5 0.3 0.9 1.3 0.3 7.6 14.0 0.1 0.7 7.2 2.9 0.5 2.6 19.4 0.6 1.9 0.0 3.8 0.2 0.5 0.0 0.1 0.6 0.0 0.9 0.2 0.0 1.6 0.0 0.1 3.9 2.1 0.1 0.2 32.8 1.6 0.8 0.4 0.0 0.3 1.6 0.0 1.4 1.0 0.6 0.0 1.1 0.0 0.4 0.0 3.6 0.8 4.9 0.5 1.5 1.6 1.0 1.3 3.7 0.3 1.8 1.4 1.9 1.0 0.0 0.2 0.7 3.6 832.1 1011.1 861.9 1288.2 774.4 799.2 864.7 904.6 859.8 798.0 925.2 1080.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.0 0.0 0.0 0.0 0.0 6.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 SERF1A "4F5, FAM2A, H4F5, SERF1, SMAM1" ENSG00000172058 "Small EDRK-rich factor 1A" O75920 5 70900669-70918530 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 64.7;testis: 43.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.1;Cone photoreceptor cells: 25.0;Rod photoreceptor cells: 26.9;Smooth muscle cells: 17.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SiHa: 111.9;SK-MEL-30: 80.5;WM-115: 59.8" HPA075271 Uncertain "Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear bodies" "HPA075271: AB_2686740" "unprognostic (1.14e-1)" "unprognostic (3.00e-2)" "unprognostic (9.58e-2)" "unprognostic (3.07e-1)" "unprognostic (1.73e-1)" "unprognostic (3.81e-3)" "unprognostic (1.29e-3)" "unprognostic (1.40e-2)" "unprognostic (2.55e-2)" "unprognostic (1.03e-1)" "unprognostic (9.83e-3)" "unprognostic (4.13e-2)" "unprognostic (2.11e-1)" "unprognostic (1.98e-2)" "unprognostic (1.22e-2)" "unprognostic (9.53e-2)" 3.9 2.6 10.1 3.2 10.5 5.8 3.3 9.6 30.3 2.4 9.7 3.4 0.5 5.6 38.3 7.5 2.3 10.9 3.8 10.2 10.4 16.2 5.6 6.2 5.7 9.8 9.7 6.4 13.4 13.7 3.7 3.2 9.9 6.1 8.1 64.7 9.5 5.5 3.4 5.5 2.5 10.5 9.0 5.3 8.4 43.7 9.7 0.6 9.5 0.1 0.4 12.5 2.7 10.3 35.9 0.2 5.5 5.6 32.6 22.0 28.3 10.3 14.7 5.0 2.1 1.0 0.3 1.8 57.9 16.4 1.1 9.7 0.8 0.4 24.9 1.3 1.3 17.4 2.2 1.0 0.3 5.6 0.6 1.1 30.6 0.2 0.5 23.5 1.0 0.3 0.2 6.3 0.2 1.6 32.8 28.8 19.7 0.0 0.2 0.2 18.4 13.9 7.1 2.6 38.5 17.3 111.9 17.2 80.5 0.4 50.0 10.6 53.8 28.4 4.3 1.8 0.5 0.5 0.5 27.4 0.5 0.1 59.8 0.1 0.8 10.2 2.9 1.6 2.8 3.5 2.5 5.0 0.2 2.8 2.0 2.1 2.6 3.2 2.6 1.5 3.5 0.6 10.1 10.5 9.6 30.3 10.2 10.4 9.8 9.7 9.9 9.0 9.7 10.3 1.7 0.0 4.2 0.3 1.9 1.9 2.7 2.4 0.6 3.9 1.8 1.3 92.1 2.8 3.2 3.7 25.0 0.3 1.5 2.4 3.9 1.7 2.8 0.8 1.2 8.2 5.4 0.0 0.5 0.5 0.4 6.2 0.0 0.7 2.5 1.5 1.4 0.2 0.5 0.0 0.4 1.0 0.0 0.3 2.1 1.2 2.1 0.5 0.0 0.0 1.3 2.4 0.0 0.0 0.4 1.0 3.2 3.8 1.2 2.3 3.1 1.5 4.2 26.9 0.0 3.1 17.1 3.0 2.0 0.3 2.3 0.1 1.9 1.4 1.8 1.0 SERPINE2 "GDN, nexin, PI7, PN1, PNI" ENSG00000135919 "Serpin family E member 2" P07093 2 223975045-224039318 "Plasma proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein, Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 1091.9" "Cell type enriched" "Detected in many" 8 "Granulosa cells: 4466.0" "Cancer enriched" "Detected in all" 9 "melanoma: 271.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 12.9;naive CD8 T-cell: 6.8;NK-cell: 23.2" "Group enriched" "Detected in many" 15 "NK-cells: 23.2;T-cells: 12.9" "Cell line enhanced" "Detected in many" "BJ: 1492.9;fHDF/TERT166: 6425.1;SK-MEL-30: 2966.9;WM-115: 2183.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000277 Approved "Golgi apparatus" "Secreted in female reproductive system" NA NA 910000 "Cluster 48: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "HPA000277: " "unprognostic (1.73e-1)" "unprognostic (7.08e-3)" "unprognostic (8.49e-2)" "unprognostic (7.78e-3)" "unprognostic (2.57e-3)" "unprognostic (5.57e-2)" "unprognostic (1.49e-2)" "unprognostic (7.43e-3)" "unprognostic (4.41e-1)" "unprognostic (7.12e-2)" "unprognostic (7.56e-3)" "unprognostic (2.40e-1)" "unprognostic (1.97e-3)" "unprognostic (1.23e-2)" "unprognostic (1.31e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.48e-5)" 28.0 19.8 120.3 75.7 125.9 6.5 14.3 128.6 158.7 28.1 71.1 22.7 28.2 17.4 5.6 36.2 20.8 46.0 100.0 115.9 145.9 39.3 10.8 14.5 30.9 158.1 152.6 145.6 8.5 3.4 8.7 1091.9 134.4 26.4 21.8 5.4 12.6 7.5 6.6 11.2 27.0 119.6 141.1 30.9 8.9 57.6 146.4 17.0 26.1 10.8 44.0 146.9 27.6 132.0 3.1 83.8 29.4 32.6 1172.5 438.7 4.4 1492.9 851.5 118.1 112.7 4.8 7.0 0.4 32.5 6425.1 188.0 5.0 3.5 102.5 101.0 0.6 26.8 16.6 49.9 22.7 57.7 12.8 1.5 128.3 68.5 342.0 505.6 304.6 9.0 5.4 0.5 1.9 412.1 4.5 2.3 3.9 56.2 31.8 92.3 10.3 25.2 64.5 1100.2 97.5 43.0 7.1 284.4 0.5 2966.9 385.2 1.2 6.4 1056.5 692.5 96.6 214.4 72.7 6.3 13.3 0.8 443.5 11.1 2183.6 0.0 0.0 0.0 0.7 0.0 0.5 0.8 0.6 0.6 0.0 1.2 12.9 6.8 0.5 23.2 0.0 0.2 0.7 2.7 120.3 125.9 128.6 158.7 115.9 145.9 158.1 152.6 134.4 141.1 146.4 132.0 13.5 0.0 1.1 233.1 3.1 23.3 16.0 132.2 351.7 5.3 7.9 8.5 5.3 0.0 4.6 7.3 0.0 106.1 11.3 19.5 11.7 13.0 2.6 5.3 17.7 20.9 24.0 23.1 86.1 33.2 524.3 556.7 5.6 5.9 2.5 4466.0 23.2 0.0 45.5 0.0 11.4 4.7 0.0 0.8 26.9 9.9 401.4 9.7 142.3 23.4 3.5 2.5 2.1 199.6 13.5 22.1 14.9 98.9 5.6 27.2 2.0 146.2 1.7 3.5 13.1 5.2 146.6 4.2 70.9 34.8 14.5 133.9 10.7 18.9 3.1 7.2 SGCD "CMD1L, DAGD, LGMD2F" ENSG00000170624 "Sarcoglycan delta" Q92629 5 155870344-156767788 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 42.9;tongue: 33.3" "Group enriched" "Detected in many" 4 "Astrocytes: 365.7;Cardiomyocytes: 107.8;Excitatory neurons: 193.0;Inhibitory neurons: 161.2;Microglial cells: 124.6;Oligodendrocyte precursor cells: 417.2;Oligodendrocytes: 196.4" "Cancer enriched" "Detected in many" 5 "melanoma: 10.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 16.1;fHDF/TERT166: 25.7;LHCN-M2: 12.7;RH-30: 18.2;SK-MEL-30: 27.0;U-138 MG: 24.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (2.23e-1)" "unprognostic (3.82e-2)" "unprognostic (9.11e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (9.55e-2)" "unprognostic (2.63e-1)" "unprognostic (1.66e-1)" "unprognostic (6.53e-2)" "unprognostic (2.25e-1)" "unprognostic (1.75e-1)" "unprognostic (6.99e-2)" "unprognostic (4.10e-2)" "unprognostic (9.65e-3)" "unprognostic (5.37e-2)" "unprognostic (5.60e-3)" "unprognostic (3.66e-3)" 5.4 4.2 3.2 2.1 2.0 0.0 3.3 1.6 3.6 6.8 0.0 7.9 2.0 8.2 2.5 6.2 2.9 9.3 39.1 2.9 2.7 1.3 2.0 5.0 0.4 4.2 3.8 8.8 1.0 9.9 1.5 0.6 4.3 6.0 3.6 1.6 1.9 5.2 42.9 1.6 2.7 13.4 3.9 1.4 2.9 1.3 2.0 0.7 17.8 33.3 0.5 6.6 3.1 6.6 0.0 6.4 0.0 0.0 5.8 9.2 0.0 16.1 5.5 0.0 0.2 0.0 0.0 0.0 0.0 25.7 0.0 0.0 3.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 8.5 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 3.0 0.1 0.0 0.0 27.0 0.0 0.0 0.0 0.0 24.1 0.0 4.3 0.0 0.1 0.1 0.0 4.1 0.0 9.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.0 1.6 3.6 2.9 2.7 4.2 3.8 4.3 3.9 2.0 6.6 0.7 0.0 0.5 365.7 0.0 3.6 0.0 0.0 0.0 3.5 4.0 2.2 107.8 0.0 0.0 0.0 54.2 0.0 1.6 0.1 0.0 0.1 6.9 6.1 1.5 1.7 1.8 0.0 193.0 0.0 0.0 27.4 0.0 16.3 0.0 11.3 3.3 1.6 0.2 21.9 161.2 0.0 0.0 0.0 2.5 13.3 19.0 0.8 24.9 124.6 0.0 0.3 0.0 417.2 196.4 0.0 0.0 15.4 0.7 0.8 0.0 0.3 0.0 1.2 0.0 38.5 5.9 0.0 0.4 0.5 3.1 0.1 1.0 9.4 0.0 0.2 SH3TC2 "CMT4C, KIAA1985" ENSG00000169247 "SH3 domain and tetratricopeptide repeats 2" Q8TF17 5 148923639-149063163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.6;retina: 3.9" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 270.4" "Cancer enhanced" "Detected in some" "melanoma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.6;HBEC3-KT: 2.2;RT4: 3.6;SK-MEL-30: 5.2;WM-115: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA037683, HPA037684" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA037683: AB_2675608, HPA037684: AB_10672603" "unprognostic (6.30e-2)" "unprognostic (4.07e-2)" "unprognostic (4.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.70e-1)" "unprognostic (1.92e-2)" "unprognostic (2.49e-1)" "unprognostic (2.17e-4)" "unprognostic (2.18e-2)" "unprognostic (4.53e-1)" "unprognostic (6.21e-3)" "unprognostic (2.20e-1)" "unprognostic (2.21e-1)" "unprognostic (6.48e-2)" "unprognostic (1.84e-1)" "unprognostic (6.62e-2)" "unprognostic (1.40e-1)" 0.1 0.0 4.7 0.0 8.0 0.1 0.1 5.1 5.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.3 3.6 5.1 0.0 0.0 0.0 0.0 7.1 6.9 0.0 0.0 0.0 0.0 0.4 7.3 0.0 0.0 3.9 0.1 0.1 0.2 0.1 0.0 0.0 5.8 0.0 0.0 1.5 7.1 0.0 0.0 0.1 0.0 0.1 0.0 12.6 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.3 0.1 2.6 1.5 0.0 1.8 0.1 0.6 1.9 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.2 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 1.1 1.6 0.0 1.3 0.0 0.7 3.6 0.0 0.0 0.0 0.0 5.2 0.1 0.0 0.0 0.2 0.1 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 8.0 5.1 5.0 3.6 5.1 7.1 6.9 7.3 5.8 7.1 12.6 1.9 3.2 3.7 0.3 0.1 0.9 0.8 1.0 0.0 1.4 0.7 0.4 1.7 1.5 3.8 0.0 4.2 0.8 0.0 0.6 0.0 0.6 6.4 0.3 0.1 2.8 0.0 0.0 0.4 0.2 0.4 0.5 0.0 0.5 2.5 0.1 1.4 0.3 0.4 0.0 0.4 0.0 2.0 1.8 0.7 2.3 0.3 2.2 0.0 4.7 0.1 2.3 0.0 0.0 270.4 1.6 0.0 0.0 0.1 1.2 0.0 0.1 4.1 25.4 0.0 0.3 0.4 2.3 0.9 1.0 0.9 11.9 0.3 0.1 0.2 8.8 SHC4 "RaLP, SHCD" ENSG00000185634 "SHC adaptor protein 4" Q6S5L8 15 48823741-48963919 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.6;testis: 10.5" "Cell type enhanced" "Detected in some" "Astrocytes: 16.6;Oligodendrocyte precursor cells: 30.7;Oligodendrocytes: 81.8" "Cancer enhanced" "Detected in some" "melanoma: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AN3-CA: 10.0;SK-MEL-30: 19.1;WM-115: 16.5" "Low region specificity" "Detected in all" HPA074146 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA074146: AB_2686667" "unprognostic (4.34e-3)" "unprognostic (1.01e-3)" "unprognostic (6.70e-2)" "unprognostic (1.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.05e-3)" "unprognostic (1.23e-2)" "unprognostic (3.47e-2)" "unprognostic (2.59e-1)" "unprognostic (2.21e-2)" "unprognostic (3.80e-2)" "unprognostic (3.71e-1)" "unprognostic (1.04e-5)" "unprognostic (9.84e-3)" "unprognostic (3.26e-2)" "unprognostic (3.49e-2)" "unprognostic (1.36e-2)" 0.5 0.9 12.7 1.0 21.0 0.1 1.6 15.8 18.9 1.0 6.7 2.8 0.3 0.4 0.9 0.5 1.0 1.4 3.3 14.0 14.3 0.3 0.1 0.3 0.3 18.3 16.9 0.5 0.2 0.1 1.0 0.4 19.0 0.7 0.5 0.9 2.1 1.3 0.9 0.6 0.8 0.7 13.6 0.2 0.7 10.5 17.8 0.3 0.3 1.2 0.1 0.4 0.9 36.6 0.0 0.4 1.0 10.0 0.4 1.3 0.0 1.5 2.9 0.6 1.2 0.0 0.3 0.1 2.6 0.6 0.1 0.0 0.2 0.4 0.8 2.2 0.1 0.6 0.0 0.0 1.1 0.0 0.2 1.9 0.0 1.3 0.1 1.3 0.1 1.0 0.0 0.2 1.4 1.9 0.4 0.2 0.1 0.0 3.7 0.2 2.7 0.3 2.1 0.4 0.5 0.8 0.2 0.1 19.1 0.9 0.0 0.1 0.0 0.9 0.5 0.6 1.0 0.9 0.1 0.1 0.8 0.5 16.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 21.0 15.8 18.9 14.0 14.3 18.3 16.9 19.0 13.6 17.8 36.6 0.2 0.0 0.0 16.6 0.0 0.3 0.0 2.3 0.0 0.6 1.6 6.7 2.5 0.0 2.8 0.0 0.0 0.7 0.0 0.0 0.0 6.4 2.5 0.4 0.4 0.2 0.0 0.0 9.3 0.0 0.2 1.8 0.0 0.3 0.0 0.0 0.7 0.0 0.1 1.7 6.1 0.0 0.0 0.0 0.4 4.5 1.2 0.1 7.2 1.0 0.0 2.7 0.0 30.7 81.8 0.2 0.0 3.4 0.0 0.0 0.0 0.1 2.6 1.0 0.0 0.5 0.3 6.0 6.3 0.1 0.3 0.8 0.3 0.5 0.0 0.0 SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 124.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 71.7;Proximal tubular cells: 192.3" "Cancer enhanced" "Detected in all" "renal cancer: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 20.4;BJ hTERT+: 20.7;CAPAN-2: 30.8;HHSteC: 19.2;hTERT-RPE1: 42.6;SK-MEL-30: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: AB_2679892, HPA060163: " "unprognostic (2.04e-1)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (2.77e-3)" "unprognostic (1.53e-1)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.70e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (3.68e-2)" "unprognostic (9.16e-2)" "unprognostic (1.71e-2)" "unprognostic (9.46e-2)" 4.9 2.9 2.7 4.6 3.1 1.0 6.9 5.8 4.4 4.2 15.4 3.6 9.5 3.0 22.4 2.7 4.0 13.7 4.6 3.5 4.1 124.1 16.3 9.2 3.4 4.1 3.1 21.4 0.9 0.4 3.8 28.6 3.9 3.8 1.6 2.3 3.6 5.8 1.3 1.3 11.4 3.4 4.1 2.7 2.7 5.2 3.0 0.6 8.5 3.9 1.1 7.9 3.5 4.2 0.4 9.8 2.3 2.7 6.3 12.9 20.4 5.3 20.7 1.8 5.3 3.1 30.8 0.6 5.7 17.1 0.1 0.5 0.1 1.9 1.9 0.5 2.5 0.5 2.7 3.3 19.2 0.9 0.5 10.0 0.3 3.0 0.2 42.6 4.1 0.8 0.5 1.2 3.3 1.0 0.4 0.6 0.9 0.0 0.3 0.2 1.3 0.1 3.7 0.4 1.2 0.9 0.6 9.8 30.6 9.0 0.7 0.1 0.4 1.4 0.7 0.3 1.5 0.5 0.1 1.6 1.1 0.4 6.1 0.0 0.2 0.1 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.1 2.7 3.1 5.8 4.4 3.5 4.1 4.1 3.1 3.9 4.1 3.0 4.2 1.9 12.8 20.8 2.3 5.8 3.1 6.1 11.2 1.2 11.5 14.7 6.5 1.1 11.5 6.8 71.7 6.2 39.5 5.8 0.9 3.9 2.7 0.5 3.3 6.8 4.6 3.5 2.7 8.2 0.9 34.6 18.2 1.5 3.3 5.1 5.2 4.2 5.0 4.2 3.3 7.1 0.9 4.1 1.6 3.0 2.2 18.0 1.8 10.6 15.0 1.8 2.4 9.2 2.5 4.7 1.9 1.2 11.7 1.2 3.1 38.4 192.3 3.5 20.1 0.0 4.5 5.4 3.4 1.9 0.5 3.7 35.2 3.9 7.0 1.4 7.2 SLC16A6 "MCT6, MCT7" ENSG00000108932 "Solute carrier family 16 member 6" O15403 17 68267026-68291267 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 51.0;epididymis: 33.3;retina: 31.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.9;Glandular and luminal cells: 27.4;Kupffer cells: 16.7;Macrophages: 21.8;Rod photoreceptor cells: 45.1" "Group enriched" "Detected in many" 6 "breast cancer: 10.9;melanoma: 11.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 13 "SK-MEL-30: 481.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054459, HPA066328" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Vesicles "HPA054459: AB_2682494, HPA066328: AB_2685660" "unprognostic (2.53e-2)" "unprognostic (2.09e-3)" "unprognostic (8.41e-2)" "unprognostic (6.94e-2)" "unprognostic (3.10e-1)" "unprognostic (5.26e-3)" "unprognostic (5.08e-3)" "unprognostic (5.39e-2)" "unprognostic (1.63e-3)" "unprognostic (1.08e-1)" "unprognostic (1.35e-2)" "unprognostic (1.44e-2)" "unprognostic (8.78e-2)" "unprognostic (2.23e-1)" "unprognostic (8.16e-3)" "unprognostic (2.09e-2)" "unprognostic (9.46e-2)" 1.5 2.7 3.0 7.2 4.8 9.7 5.8 4.3 4.3 1.6 51.0 0.7 0.5 2.6 33.3 10.9 0.9 1.3 0.9 5.0 5.2 0.7 1.4 3.0 5.3 5.1 4.2 1.5 0.5 0.1 1.7 2.3 5.3 0.6 0.8 31.0 2.2 4.2 5.0 4.5 1.2 0.8 2.4 5.7 1.0 2.3 5.2 1.6 3.5 0.7 4.7 2.1 2.6 3.2 2.1 1.8 0.6 0.8 0.4 0.6 14.2 0.8 18.0 1.7 1.2 0.7 2.5 17.6 1.4 0.0 0.2 0.6 2.5 0.0 0.7 5.4 1.3 1.4 2.2 22.3 3.2 5.7 1.1 0.8 0.2 1.0 1.0 1.7 0.8 2.5 1.1 3.8 0.0 18.1 8.5 3.6 0.2 0.1 1.0 0.1 0.4 2.4 0.8 1.5 4.2 0.3 0.8 10.7 481.5 3.8 15.0 3.5 2.7 5.9 1.1 0.5 2.0 4.2 17.5 14.6 36.0 4.6 2.6 0.8 3.1 0.2 1.8 2.7 0.8 0.4 0.6 1.4 1.9 0.0 0.4 0.8 5.4 0.4 1.4 0.3 1.5 0.9 3.0 4.8 4.3 4.3 5.0 5.2 5.1 4.2 5.3 2.4 5.2 3.2 0.6 0.0 2.5 1.6 1.8 0.3 0.2 0.1 1.2 8.2 2.5 0.9 0.8 0.0 4.0 9.2 22.9 0.4 8.4 0.0 0.0 0.0 0.7 4.7 2.5 3.2 0.0 2.7 6.7 0.0 11.5 0.9 0.5 27.4 1.3 0.1 0.7 0.3 5.6 0.0 6.2 0.0 0.0 16.7 7.0 0.3 0.0 21.8 10.6 4.7 11.1 6.2 5.2 0.5 0.8 0.0 0.0 1.9 5.0 0.2 0.0 0.3 1.6 45.1 0.0 0.8 0.3 1.7 0.7 6.7 0.4 0.4 5.3 0.4 0.1 0.2 SLC19A2 "THTR1, TRMA" ENSG00000117479 "Solute carrier family 19 member 2" O60779 1 169463909-169485944 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 124.1;tongue: 84.9" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 84.5;Syncytiotrophoblasts: 156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006119, HPA016599" Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA006119: AB_1079996, HPA016599: AB_1857005" "prognostic favorable (8.41e-4)" "unprognostic (8.82e-2)" "unprognostic (1.90e-1)" "unprognostic (3.29e-3)" "prognostic favorable (2.90e-4)" "unprognostic (4.45e-2)" "unprognostic (9.69e-2)" "unprognostic (1.45e-1)" "unprognostic (2.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (3.60e-2)" "unprognostic (2.14e-2)" 42.2 17.8 3.0 8.3 3.1 8.7 20.9 5.1 4.2 10.5 9.3 11.8 3.5 8.6 6.1 11.3 21.3 25.8 31.2 4.0 3.6 13.0 37.1 19.5 2.6 4.9 3.7 20.5 22.2 24.8 19.0 18.1 4.0 10.5 4.3 7.5 12.5 3.8 124.1 16.5 11.4 6.1 3.7 2.8 19.2 7.8 4.2 4.1 15.7 84.9 2.8 18.1 12.9 3.5 7.4 5.1 11.4 9.0 34.4 12.7 25.0 5.8 4.3 4.6 6.5 20.9 7.6 6.5 6.4 3.9 8.5 7.7 13.9 8.5 5.1 18.8 13.0 6.2 16.7 19.3 18.7 15.8 5.9 15.0 12.2 7.4 18.8 6.4 7.0 11.3 25.3 4.1 7.9 5.0 8.2 7.1 25.8 14.1 7.7 0.0 24.6 7.5 12.2 15.5 9.9 13.3 8.0 13.6 29.2 12.8 8.5 10.1 5.8 5.5 7.7 6.9 11.4 5.6 5.6 2.1 8.1 6.0 7.4 0.0 0.6 1.1 0.3 0.2 1.1 0.4 0.4 0.7 0.7 0.4 1.0 1.0 0.4 0.9 2.0 0.2 0.3 0.2 3.0 3.1 5.1 4.2 4.0 3.6 4.9 3.7 4.0 3.7 4.2 3.5 13.6 9.6 19.3 11.8 7.3 29.6 16.5 4.4 43.9 5.3 34.1 13.6 27.7 7.2 11.4 5.5 2.1 26.9 11.3 10.6 0.0 7.4 4.3 22.6 9.7 3.7 9.0 5.2 15.6 5.3 4.5 52.7 49.5 42.7 10.2 4.1 1.1 29.8 7.0 6.7 22.8 6.4 12.2 2.9 8.8 2.7 6.8 18.3 21.4 7.5 1.0 2.5 2.1 16.1 3.3 9.6 5.4 4.9 14.0 16.5 5.6 2.0 12.7 5.1 0.0 84.5 14.2 6.7 4.1 35.2 50.4 156.4 7.5 3.1 6.7 28.9 SLC1A4 "ASCT1, SATT" ENSG00000115902 "Solute carrier family 1 member 4" P43007 2 64988477-65023865 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.9" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Granulosa cells: 49.2;Melanocytes: 85.4;Plasma cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 294.5;U-266/70: 132.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034963, HPA034964" Approved Enhanced Centrosome NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Centrosome "HPA034963: AB_2797223, HPA034964: AB_2674386" "unprognostic (7.61e-2)" "prognostic favorable (3.59e-4)" "unprognostic (2.49e-1)" "unprognostic (3.19e-3)" "unprognostic (1.26e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.23e-5)" "unprognostic (1.26e-2)" "unprognostic (2.10e-1)" "unprognostic (3.16e-2)" "unprognostic (2.28e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (4.87e-4)" "unprognostic (6.37e-3)" "unprognostic (4.14e-2)" "unprognostic (3.53e-2)" "unprognostic (1.98e-2)" 4.3 26.4 49.1 9.1 46.8 13.4 13.6 32.1 48.6 14.0 18.0 9.4 6.1 12.8 8.2 7.5 4.8 3.9 6.2 43.4 56.6 1.9 9.0 4.9 10.7 37.2 43.1 13.2 29.6 5.5 13.7 6.6 52.1 9.6 8.4 19.3 7.5 7.1 40.1 18.6 5.6 12.3 29.5 7.5 8.1 11.7 59.9 20.5 5.7 17.0 19.0 4.8 6.2 30.3 15.3 11.6 6.6 34.9 14.7 9.5 9.4 28.5 14.0 11.7 19.8 3.2 2.2 49.7 6.5 44.8 14.7 43.2 13.7 3.6 12.0 20.1 5.4 26.0 13.1 30.9 31.0 43.8 23.1 4.4 73.8 15.8 24.2 3.9 7.3 49.1 20.7 122.0 8.4 13.5 37.7 29.1 4.7 20.1 13.9 13.5 1.9 125.5 4.9 7.7 29.3 14.1 17.9 16.1 294.5 3.0 19.3 47.8 1.6 16.0 19.0 31.2 17.5 132.8 71.2 118.8 23.6 86.5 86.2 0.0 2.1 1.8 0.9 4.8 1.2 0.9 0.9 1.5 3.9 0.3 0.0 0.8 0.0 5.1 9.4 7.2 3.5 1.4 49.1 46.8 32.1 48.6 43.4 56.6 37.2 43.1 52.1 29.5 59.9 30.3 3.6 0.0 2.7 69.9 13.6 20.0 2.1 6.7 46.1 6.3 21.0 7.1 5.5 1.5 1.7 1.8 33.3 2.4 20.2 2.9 0.0 2.0 32.4 5.4 8.2 5.3 8.4 6.1 20.6 9.3 1.3 4.0 5.1 5.6 7.0 49.2 7.5 13.1 17.7 6.7 25.5 9.0 6.1 6.8 11.8 47.5 11.1 11.1 85.4 8.4 5.1 14.6 2.1 5.0 3.9 7.1 0.8 29.7 65.7 2.6 0.4 1.5 5.4 17.7 0.0 5.1 7.3 2.0 0.9 5.9 6.1 2.5 10.9 0.4 5.8 1.0 SLC22A18AS "BWR1B, BWSCR1B, ORCTL2S, p27-BWR1B, SLC22A1LS" ENSG00000254827 "Solute carrier family 22 member 18 antisense" Q8N1D0 11 2887344-2903575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 17.7;kidney: 11.1;liver: 14.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 163.3;Paneth cells: 124.4;Proximal enterocytes: 75.7;Proximal tubular cells: 104.0;Syncytiotrophoblasts: 80.7;Undifferentiated cells: 48.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 7.0" "Group enriched" "Detected in many" 8 "dendritic cells: 3.9;granulocytes: 4.0;monocytes: 7.0" "Cell line enhanced" "Detected in some" "A549: 9.4;CAPAN-2: 9.4;MCF7: 18.8;OE19: 8.4;SK-MEL-30: 35.8;WM-115: 14.8" HPA068288 Enhanced Approved Nucleoplasm No NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA068288: AB_2685969" "unprognostic (1.43e-1)" "unprognostic (9.21e-2)" "unprognostic (3.36e-1)" "unprognostic (8.05e-2)" "unprognostic (1.33e-3)" "unprognostic (3.16e-2)" "unprognostic (5.14e-3)" "unprognostic (9.76e-2)" "unprognostic (1.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.10e-2)" "unprognostic (1.48e-2)" "unprognostic (9.52e-2)" "unprognostic (1.77e-1)" "unprognostic (2.39e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" 3.2 0.6 0.5 2.2 0.6 0.2 0.7 0.5 1.7 0.7 0.5 17.7 13.4 0.8 0.4 1.2 0.4 1.7 0.3 0.6 1.0 11.1 14.9 0.6 0.4 0.9 0.9 0.4 0.3 0.0 0.3 2.3 1.1 0.8 10.2 0.3 1.8 0.1 0.1 1.1 9.7 0.7 0.8 0.7 1.6 0.5 0.8 0.1 0.3 0.0 0.1 0.7 0.9 1.1 1.2 9.4 0.3 0.5 0.0 0.0 0.9 0.5 0.4 0.0 0.2 2.2 9.4 0.0 0.8 0.0 0.6 0.5 0.0 0.3 0.0 0.4 0.1 0.0 0.8 5.8 0.7 0.0 0.1 0.1 0.3 0.0 0.6 0.4 0.3 0.5 0.0 0.9 0.0 18.8 0.0 0.4 0.2 8.4 0.3 0.3 0.0 1.0 0.8 0.0 0.1 0.3 0.9 0.4 35.8 0.2 0.0 0.9 1.9 0.0 0.7 0.3 0.2 0.0 0.0 0.2 0.2 2.6 14.8 4.0 7.0 1.2 0.2 3.9 0.1 0.0 0.1 0.2 3.9 0.0 0.0 0.1 1.6 0.4 2.9 0.0 0.6 2.4 0.5 0.6 0.5 1.7 0.6 1.0 0.9 0.9 1.1 0.8 0.8 1.1 0.6 0.0 0.5 0.0 1.3 0.5 1.1 6.3 1.2 0.0 1.2 0.9 0.4 1.5 2.7 7.3 0.0 19.5 0.4 163.3 9.8 1.7 0.1 0.1 0.3 0.7 9.1 3.2 0.4 0.8 9.8 1.4 2.6 0.5 1.3 0.0 2.9 22.7 17.7 0.0 0.1 26.2 6.1 6.3 5.5 0.2 0.3 6.4 3.6 0.0 4.6 0.0 0.0 0.0 0.1 2.4 124.4 0.0 0.0 1.0 75.7 104.0 1.0 0.0 0.0 0.0 0.6 0.1 0.4 2.1 1.1 80.7 0.9 0.8 48.5 2.5 SLC23A2 "KIAA0238, SLC23A1, SVCT2, YSPL2" ENSG00000089057 "Solute carrier family 23 member 2" Q9UGH3 20 4852356-5010293 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 99.3;choroid plexus: 88.4;retina: 107.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 236.8;Cone photoreceptor cells: 114.7;Excitatory neurons: 102.8;Inhibitory neurons: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052825, HPA059314" Approved Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" Vesicles "Golgi apparatus" "HPA052825: AB_2681965, HPA059314: AB_2683975" "unprognostic (3.83e-1)" "unprognostic (1.08e-2)" "unprognostic (1.95e-3)" "unprognostic (1.64e-3)" "unprognostic (8.05e-2)" "unprognostic (2.09e-1)" "prognostic favorable (3.35e-4)" "unprognostic (6.22e-3)" "unprognostic (2.08e-1)" "unprognostic (6.36e-3)" "prognostic favorable (7.14e-5)" "unprognostic (1.57e-1)" "unprognostic (1.60e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.08e-5)" 10.2 99.3 26.3 8.2 27.2 7.8 9.4 24.1 26.0 13.5 88.4 9.4 6.4 12.9 8.7 6.1 15.9 10.1 8.3 28.5 26.7 13.0 57.0 12.1 10.2 28.1 32.0 38.5 10.0 17.7 23.3 8.1 29.5 12.5 6.1 107.2 5.9 10.3 3.3 11.4 12.5 10.0 25.6 20.9 9.4 11.4 34.6 8.2 25.0 4.5 9.9 18.9 8.9 33.1 21.2 24.5 32.2 12.2 22.2 12.4 40.9 8.9 12.1 10.3 9.6 12.7 23.6 9.6 9.4 12.4 29.1 20.1 9.1 24.2 19.2 6.0 16.2 13.3 4.3 48.0 12.5 18.9 7.6 10.6 13.8 25.8 15.4 21.5 15.2 15.5 9.3 7.9 13.7 7.9 20.7 10.5 11.4 16.9 14.9 19.0 21.2 14.3 5.6 34.2 10.7 12.0 17.0 17.7 63.3 11.4 9.8 10.9 13.1 23.0 10.7 27.8 17.4 11.2 22.2 25.5 8.1 11.2 36.8 0.0 1.1 0.1 1.1 0.7 1.0 1.8 0.8 0.8 1.5 1.0 0.8 0.8 1.2 0.3 0.9 2.4 0.5 0.9 26.3 27.2 24.1 26.0 28.5 26.7 28.1 32.0 29.5 25.6 34.6 33.1 9.3 6.4 7.2 50.3 14.5 7.4 4.5 7.0 12.5 236.8 8.3 7.4 7.9 15.7 9.4 14.7 114.7 4.9 12.6 0.8 0.0 5.0 4.6 2.8 10.1 13.0 7.2 8.6 102.8 5.5 6.6 14.2 3.6 1.9 8.2 13.5 17.5 71.3 10.6 85.8 117.4 1.9 0.0 30.2 7.5 9.3 20.2 16.3 16.0 60.0 8.8 24.8 7.2 77.4 78.3 3.4 6.7 29.3 11.9 8.2 0.6 1.3 7.8 71.5 13.1 12.6 12.2 0.6 8.0 5.5 6.1 4.0 8.2 65.6 2.8 14.7 SLC24A5 "JSX, OCA6" ENSG00000188467 "Solute carrier family 24 member 5" Q71RS6 15 48120990-48142672 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport" Albinism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 8.2" "Group enriched" "Detected in some" 7 "Early spermatids: 20.7;Melanocytes: 76.5" "Cancer enriched" "Detected in single" 162 "melanoma: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 800 "SK-MEL-30: 251.8" "Group enriched" "Detected in some" 5 "hippocampal formation: 3.0;pons and medulla: 4.1;thalamus: 1.5" "Low region specificity" "Detected in all" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (3.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.35e-1)" "unprognostic (1.92e-3)" 0.0 0.0 0.3 0.0 0.3 0.0 0.2 0.3 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.1 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 251.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.2 0.1 0.5 0.1 0.9 0.2 0.0 0.9 0.2 0.3 0.0 0.5 0.7 0.2 2.4 0.0 0.0 0.0 6.4 0.0 0.1 0.3 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 20.7 1.5 0.1 0.1 0.0 0.4 2.9 0.0 0.0 0.5 0.0 0.9 0.0 0.1 0.0 0.0 0.1 5.0 2.7 0.0 0.0 0.0 0.7 6.6 0.0 0.0 76.5 1.0 0.0 0.9 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 4.6 0.0 0.1 0.1 0.1 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 SLC25A34 DKFZp781A10161 ENSG00000162461 "Solute carrier family 25 member 34" Q6PIV7 1 15736258-15741392 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "heart muscle: 14.4;intestine: 14.0;skeletal muscle: 37.8;tongue: 47.3" "Cell type enriched" "Detected in many" 5 "Proximal enterocytes: 44.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069806 Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA069806: AB_2686202" "unprognostic (2.06e-1)" "unprognostic (4.72e-1)" "unprognostic (1.15e-1)" "unprognostic (2.43e-1)" "unprognostic (2.58e-1)" "unprognostic (8.08e-3)" "unprognostic (1.98e-2)" "unprognostic (9.92e-2)" "unprognostic (1.55e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-4)" "unprognostic (5.74e-2)" "unprognostic (6.10e-2)" "unprognostic (4.02e-1)" "unprognostic (1.82e-1)" "unprognostic (4.04e-2)" "unprognostic (2.40e-4)" 2.4 4.4 3.7 1.0 3.8 3.4 1.8 6.8 4.8 3.6 2.4 5.7 14.0 3.1 0.8 1.7 2.9 1.5 14.4 3.6 3.4 4.7 5.6 2.4 1.2 3.2 3.1 4.2 4.9 0.6 3.8 1.3 3.5 2.4 2.0 1.9 4.7 0.8 37.8 1.8 13.7 1.1 2.7 3.7 2.2 2.5 3.7 0.5 3.4 47.3 0.5 2.8 2.3 3.6 0.3 0.2 1.5 0.6 0.7 0.3 0.6 0.2 0.1 0.3 0.2 0.6 0.8 0.4 0.3 0.3 0.8 0.3 0.2 0.2 0.3 0.5 0.3 0.7 0.5 0.2 0.2 0.2 0.9 0.3 1.1 0.4 0.1 0.9 0.2 2.0 0.3 1.3 0.2 0.7 1.7 0.9 1.3 0.2 0.4 0.9 1.3 0.4 0.1 0.0 0.3 1.2 0.3 0.4 3.4 1.4 0.7 1.0 0.8 0.7 1.0 1.0 0.2 1.7 1.6 0.3 0.2 0.9 0.6 0.5 0.1 0.1 0.4 0.0 0.9 0.1 0.9 0.6 0.0 0.2 1.2 0.7 0.6 0.6 0.0 0.1 0.4 0.3 3.7 3.8 6.8 4.8 3.6 3.4 3.2 3.1 3.5 2.7 3.7 3.6 0.9 0.0 0.0 6.2 0.4 0.3 0.3 0.6 0.0 2.6 0.5 0.5 2.7 1.5 0.2 0.0 0.0 0.3 0.3 8.8 0.0 0.2 0.3 0.4 1.3 1.2 3.5 0.0 5.1 0.2 0.4 0.8 2.0 1.7 0.0 1.3 2.2 2.3 1.5 3.3 4.6 3.1 0.0 1.9 0.3 1.0 0.9 1.5 0.0 2.8 1.1 1.8 0.0 2.5 1.7 0.3 8.0 0.4 0.0 0.6 44.6 3.7 0.0 1.8 0.0 2.7 0.9 0.6 0.6 1.1 0.1 1.4 0.6 0.4 5.5 0.7 SLC25A36 "FLJ10618, PNC2" ENSG00000114120 "Solute carrier family 25 member 36" Q96CQ1 3 140941830-140980995 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027036 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "Mitochondria, Cytosol" Nucleoplasm "HPA027036: AB_1857048" "unprognostic (4.12e-2)" "unprognostic (9.98e-2)" "unprognostic (2.86e-1)" "unprognostic (1.37e-1)" "unprognostic (6.52e-2)" "unprognostic (3.46e-1)" "unprognostic (9.00e-2)" "unprognostic (1.71e-2)" "unprognostic (1.99e-2)" "unprognostic (2.47e-2)" "unprognostic (3.82e-1)" "unprognostic (2.10e-2)" "unprognostic (2.33e-1)" "unprognostic (1.20e-1)" "unprognostic (2.34e-1)" "unprognostic (6.03e-2)" "prognostic favorable (1.55e-4)" 27.1 22.2 16.6 14.3 16.2 61.6 33.5 16.2 22.7 31.9 13.9 25.7 30.9 34.4 47.7 15.0 32.6 18.4 39.8 16.1 20.1 38.7 4.2 27.5 21.3 17.0 16.4 39.0 45.2 28.9 26.9 26.4 17.5 27.1 19.5 42.6 23.4 20.8 38.4 22.5 22.9 19.2 16.9 20.1 34.0 23.8 18.2 20.6 31.8 20.8 17.6 23.0 23.9 21.5 52.3 11.5 36.0 30.8 33.0 40.7 46.2 19.4 23.6 18.2 27.3 28.6 24.0 42.1 46.9 17.3 31.2 34.9 40.1 15.2 40.6 33.8 36.5 33.9 29.8 20.9 45.9 48.8 21.3 44.1 61.1 15.4 45.8 44.4 22.0 32.0 17.6 27.4 29.2 22.8 30.6 34.1 37.8 12.8 18.4 34.2 32.0 59.6 23.5 17.7 22.4 38.2 26.7 45.1 80.9 30.3 32.6 29.2 24.1 29.5 17.1 52.2 19.0 56.4 36.8 51.2 36.0 21.1 15.0 10.7 9.2 15.1 9.6 11.5 11.8 16.3 9.6 10.2 14.0 15.1 13.5 12.6 1.7 18.3 13.5 9.7 9.9 9.8 16.6 16.2 16.2 22.7 16.1 20.1 17.0 16.4 17.5 16.9 18.2 21.5 60.3 99.3 143.0 85.5 47.6 68.2 68.0 38.1 116.7 106.0 72.2 77.5 90.3 38.6 52.0 71.7 133.5 58.8 58.2 22.7 64.6 26.4 10.6 113.4 78.0 45.8 59.3 27.3 127.7 38.3 38.0 73.9 58.1 106.3 65.9 92.8 35.7 0.5 26.5 92.5 115.6 32.5 30.5 38.2 45.8 16.0 59.7 38.4 56.9 46.9 36.9 68.2 25.7 108.6 109.1 29.3 22.8 59.5 48.2 88.9 44.9 57.5 98.8 121.8 59.2 80.0 59.2 59.4 68.8 61.3 54.4 49.4 49.1 83.2 46.8 78.9 SLC25A4 "ANT1, PEO2, PEO3, T1" ENSG00000151729 "Solute carrier family 25 member 4" P12235 4 185143266-185150382 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Host-virus interaction, Transport" "Cardiomyopathy, Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "heart muscle: 245.1;skeletal muscle: 190.8;tongue: 346.6" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 4722.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 380000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (4.19e-2)" "unprognostic (1.06e-2)" "unprognostic (3.11e-1)" "unprognostic (8.85e-2)" "unprognostic (1.37e-1)" "unprognostic (2.90e-3)" "unprognostic (8.25e-2)" "unprognostic (1.26e-2)" "unprognostic (7.87e-2)" "unprognostic (1.60e-1)" "prognostic favorable (3.41e-4)" "unprognostic (2.05e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (1.73e-1)" "unprognostic (8.28e-3)" 4.7 5.7 14.0 1.6 15.3 0.4 4.6 22.6 30.6 3.4 6.8 21.0 3.0 5.9 3.5 10.1 5.8 3.9 245.1 16.7 11.8 10.4 7.3 4.5 1.5 11.6 10.7 4.9 5.2 7.8 9.5 1.7 11.8 8.9 3.9 19.9 9.0 12.6 190.8 3.3 6.8 8.1 9.4 3.1 15.7 4.7 12.5 1.4 5.2 346.6 1.2 9.8 3.6 18.2 0.7 3.1 2.5 5.1 2.7 0.3 4.6 2.6 0.8 3.1 3.0 6.8 1.7 2.3 1.8 3.1 2.4 2.5 9.8 2.7 2.0 3.9 8.4 1.6 4.7 8.1 5.5 1.4 1.5 2.0 6.6 4.7 1.3 7.2 2.3 4.0 3.8 1.7 1.9 5.0 1.6 3.1 4.1 2.2 6.6 2.5 1.3 3.2 6.9 4.8 8.1 6.2 3.1 1.3 12.5 4.5 2.4 1.1 1.7 0.2 1.4 1.5 3.4 7.3 3.5 2.9 2.2 0.3 2.8 0.0 0.0 0.0 1.7 0.0 1.3 1.5 0.5 1.4 0.0 1.0 0.4 1.2 0.1 0.3 0.0 1.3 0.5 0.6 14.0 15.3 22.6 30.6 16.7 11.8 11.6 10.7 11.8 9.4 12.5 18.2 37.5 86.6 76.4 22.9 37.9 44.1 159.0 119.9 30.1 180.6 42.9 53.5 4722.0 115.8 80.0 71.7 104.3 69.2 41.1 44.4 988.0 75.3 20.6 77.8 7.4 80.1 53.8 3.0 35.1 74.1 56.5 120.1 54.0 33.6 12.0 18.6 27.5 92.1 65.9 159.9 43.7 40.6 215.7 8.5 13.8 16.7 46.6 6.8 190.3 19.7 9.0 541.2 16.5 26.7 29.2 51.4 28.5 112.8 76.4 59.1 113.8 178.3 144.0 221.0 105.2 134.5 402.7 28.0 34.0 33.2 18.2 40.5 27.7 23.7 54.2 50.7 SLC27A1 "ACSVL5, FATP, FATP1, FLJ00336, MGC71751" ENSG00000130304 "Solute carrier family 27 member 1" Q6PCB7 19 17468769-17506168 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Oligodendrocytes: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 27.7;SK-MEL-30: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076520 Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Mitochondria, Cytosol" "HPA076520: AB_2732311" "unprognostic (1.48e-3)" "unprognostic (3.03e-2)" "unprognostic (5.72e-3)" "unprognostic (5.84e-2)" "unprognostic (2.16e-3)" "unprognostic (4.36e-2)" "unprognostic (8.56e-2)" "unprognostic (3.36e-2)" "unprognostic (9.03e-2)" "unprognostic (1.85e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "prognostic favorable (4.70e-4)" "unprognostic (5.01e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" 18.5 24.2 32.9 4.5 41.5 1.5 19.3 37.3 39.0 22.0 45.9 15.2 3.6 13.1 2.9 8.5 17.0 8.2 29.0 32.0 32.8 10.9 7.9 10.4 4.7 41.1 40.3 33.0 14.4 17.7 19.3 6.2 38.6 23.2 1.8 4.0 24.1 10.3 24.9 14.4 7.6 3.9 34.4 10.5 13.7 17.5 35.9 2.2 16.8 12.4 1.6 13.9 14.0 46.7 6.2 3.0 4.1 9.8 27.7 15.2 3.5 4.4 11.2 4.8 7.2 0.5 18.2 2.1 8.1 7.2 4.3 7.3 0.4 6.8 1.3 2.4 1.4 1.2 0.5 2.3 5.4 0.5 6.4 14.1 4.6 4.8 1.9 19.7 3.3 3.9 0.8 1.3 3.2 2.5 3.3 4.9 1.2 6.0 5.2 4.7 3.2 1.4 3.2 1.8 1.4 2.9 3.0 1.5 47.8 2.5 5.2 1.6 2.1 9.4 6.1 7.5 3.0 4.0 3.1 0.7 9.6 5.3 6.7 0.0 9.2 0.2 1.4 4.0 2.6 0.4 1.0 1.7 6.3 0.3 1.3 1.7 0.0 1.6 1.8 6.5 0.7 4.6 32.9 41.5 37.3 39.0 32.0 32.8 41.1 40.3 38.6 34.4 35.9 46.7 19.7 3.2 11.9 84.5 1.8 6.6 14.1 12.7 10.2 8.4 15.5 26.9 19.5 11.5 11.1 9.2 27.1 4.3 8.3 1.2 1.9 11.1 1.1 8.4 6.9 7.8 5.4 0.8 16.1 4.8 15.6 10.4 9.2 4.9 2.5 8.4 10.4 8.1 26.1 6.7 23.9 3.0 6.1 22.4 4.0 2.5 21.5 13.4 8.8 15.0 14.7 11.6 4.1 37.2 67.5 5.2 0.6 11.7 1.7 12.0 0.1 3.6 16.1 17.7 6.6 10.9 7.3 9.1 5.8 5.0 4.5 2.3 4.9 13.8 2.2 8.7 SLC2A10 GLUT10 ENSG00000197496 "Solute carrier family 2 member 10" O95528 20 46709649-46736347 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 43.6;Intestinal goblet cells: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 75 "basophil: 20.9" "Lineage enriched" "Detected in single" 75 "granulocytes: 20.9" "Cell line enhanced" "Detected in many" "ASC diff: 45.8;HSkMC: 56.6;OE19: 49.8;SK-MEL-30: 60.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041015, HPA055673" Approved Supported Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA041015: AB_2677252, HPA055673: AB_2682879" "unprognostic (8.94e-3)" "unprognostic (2.62e-3)" "unprognostic (2.06e-1)" "unprognostic (1.85e-1)" "unprognostic (6.17e-3)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.80e-1)" "unprognostic (1.83e-1)" "unprognostic (8.06e-2)" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (3.63e-3)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-1)" "unprognostic (5.96e-2)" 7.0 5.9 4.0 3.5 4.1 1.2 15.3 3.4 3.9 19.4 18.9 12.7 5.4 7.9 8.7 5.1 9.9 10.3 5.2 3.8 3.7 3.5 41.4 6.9 1.7 5.2 4.7 9.9 17.4 19.5 6.3 11.6 4.0 31.3 16.0 1.6 24.0 9.9 1.5 3.6 5.3 8.5 3.8 2.6 22.8 2.6 4.0 1.6 19.5 2.7 2.1 9.3 8.4 3.4 0.0 0.1 11.3 11.7 45.8 38.9 34.2 22.2 30.2 10.1 12.0 0.9 38.9 0.0 16.3 40.6 0.0 0.2 0.0 1.1 4.8 0.0 0.3 3.3 0.0 18.6 32.2 0.0 0.0 56.6 1.0 6.2 0.0 11.8 4.2 0.0 0.2 0.1 17.5 41.3 0.0 1.2 4.3 49.8 2.9 0.0 1.6 0.1 0.0 10.6 0.0 1.8 4.3 7.2 60.3 8.1 5.4 9.2 2.6 21.7 9.1 17.2 2.9 0.3 0.1 0.0 0.1 0.0 4.6 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 4.0 4.1 3.4 3.9 3.8 3.7 5.2 4.7 4.0 3.8 4.0 3.4 4.2 6.4 6.3 12.4 0.8 0.6 6.1 7.8 5.2 0.0 29.6 14.4 6.4 7.2 15.8 1.8 0.0 2.7 0.4 11.4 0.0 7.4 0.2 3.2 17.8 4.6 3.6 6.1 0.1 5.6 16.3 16.7 23.4 4.0 6.3 10.7 8.6 43.6 1.1 0.0 0.4 56.6 12.2 1.9 1.3 1.6 26.4 0.4 1.8 2.8 0.0 5.5 0.0 10.1 0.3 5.1 10.3 17.3 2.8 23.9 1.7 0.8 27.5 0.5 13.1 5.1 6.3 0.8 0.3 4.2 1.0 2.1 0.5 3.6 14.6 10.9 SLC31A1 "COPT1, CTR1, hCTR1" ENSG00000136868 "Solute carrier family 31 member 1" O15431 9 113221544-113264492 "Metabolic proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 107.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 20.9;intermediate monocyte: 26.8;myeloid DC: 16.3;neutrophil: 8.2;non-classical monocyte: 31.0" "Group enriched" "Detected in all" 4 "dendritic cells: 16.3;granulocytes: 8.2;monocytes: 31.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013810 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "HPA013810: AB_1857095" "unprognostic (1.22e-2)" "unprognostic (1.74e-1)" "unprognostic (4.29e-2)" "unprognostic (5.48e-3)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (6.99e-3)" "unprognostic (7.58e-2)" "unprognostic (2.30e-1)" "unprognostic (2.51e-1)" "unprognostic (7.18e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.20e-6)" "unprognostic (1.22e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.51e-2)" 11.5 23.9 5.7 11.1 5.8 11.7 12.7 6.6 6.5 20.7 26.3 16.3 45.1 7.2 13.7 12.0 6.5 9.6 7.4 6.9 6.6 28.7 107.6 17.7 6.3 7.2 6.9 4.9 19.1 15.2 5.8 13.5 11.7 21.3 17.0 7.1 66.5 12.8 3.5 18.5 37.4 10.0 6.8 7.6 19.4 6.4 7.0 5.5 10.9 5.8 12.4 14.3 6.5 6.5 22.1 23.4 18.7 41.4 42.0 29.8 68.8 38.3 58.0 26.0 30.1 33.5 18.8 17.2 15.2 33.0 32.9 53.3 35.8 21.8 29.0 15.2 19.9 14.2 18.7 37.6 102.3 26.1 20.6 36.1 48.3 33.6 54.6 17.4 24.0 19.6 32.8 30.9 24.8 23.6 17.9 13.2 30.4 84.2 26.0 18.3 49.1 17.2 23.6 27.2 17.7 23.1 37.0 73.0 101.5 26.2 37.2 22.0 22.3 19.3 11.9 39.1 23.2 18.5 40.5 23.6 31.9 24.2 23.1 3.0 20.9 2.5 2.3 26.8 3.2 1.7 1.6 2.4 16.3 1.5 1.8 1.7 8.2 4.4 31.0 2.3 1.8 7.6 5.7 5.8 6.6 6.5 6.9 6.6 7.2 6.9 11.7 6.8 7.0 6.5 8.0 35.3 33.5 7.5 6.6 15.2 10.6 27.4 10.2 12.6 21.4 14.9 7.4 21.5 50.8 5.5 33.3 16.5 6.9 40.2 9.8 18.3 0.3 16.2 15.6 11.6 9.0 25.4 16.8 27.2 24.1 16.0 15.3 14.5 5.1 11.4 11.4 97.1 43.4 6.7 17.0 18.9 42.7 39.4 19.9 0.9 6.2 40.3 12.4 20.6 21.8 12.2 4.1 16.1 12.3 22.3 11.1 7.2 16.1 28.9 61.7 24.7 30.1 11.2 6.6 8.4 15.2 24.4 30.7 15.1 15.8 22.4 5.5 15.2 19.9 22.6 SLC35A5 FLJ20730 ENSG00000138459 "Solute carrier family 35 member A5" Q9BS91 3 112561709-112585579 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early spermatids: 156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035519, HPA057964" Uncertain Approved "Golgi apparatus" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus" "HPA035519: AB_10601487, HPA057964: AB_2683566" "unprognostic (7.89e-2)" "unprognostic (2.33e-1)" "unprognostic (7.17e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-1)" "unprognostic (7.09e-2)" "unprognostic (1.45e-1)" "unprognostic (4.78e-2)" "unprognostic (8.60e-3)" "unprognostic (2.60e-1)" "unprognostic (8.21e-2)" "unprognostic (3.51e-1)" "prognostic favorable (4.10e-5)" "unprognostic (2.26e-1)" "unprognostic (1.97e-1)" "unprognostic (8.05e-2)" "unprognostic (3.42e-1)" 15.5 19.3 18.2 13.4 23.9 5.7 14.8 22.4 26.9 15.5 18.4 15.6 16.7 15.6 16.0 14.3 14.6 15.4 9.7 18.1 21.4 20.2 21.0 14.7 15.7 24.0 21.7 17.9 9.5 17.2 9.1 18.4 24.3 16.0 16.1 21.7 11.4 13.9 6.1 9.2 18.3 15.9 23.2 14.2 14.5 18.8 21.2 12.7 26.1 10.2 15.3 12.6 8.3 30.0 20.4 18.4 31.2 18.8 39.3 37.4 18.0 33.2 23.7 27.5 31.5 13.6 22.8 18.1 27.4 28.8 31.3 25.3 22.4 15.6 34.6 14.2 11.1 23.2 15.9 11.4 33.6 20.7 21.5 31.8 30.9 24.3 14.9 34.8 25.1 13.8 13.5 22.1 38.7 7.2 16.2 13.1 20.8 24.0 19.2 14.4 11.4 19.7 34.2 14.9 18.3 24.1 21.3 10.4 38.0 20.9 14.2 13.9 28.3 40.3 21.8 8.6 15.7 15.7 24.4 32.2 29.9 17.2 30.8 14.8 16.4 21.0 10.9 25.9 10.3 14.7 10.2 8.6 19.7 13.6 13.6 11.2 14.6 7.3 27.4 9.4 11.2 10.8 18.2 23.9 22.4 26.9 18.1 21.4 24.0 21.7 24.3 23.2 21.2 30.0 9.9 3.2 10.1 13.1 12.5 6.4 8.3 9.9 11.4 12.8 8.5 6.5 5.5 7.2 12.6 14.7 0.0 36.1 12.5 16.4 9.8 7.8 156.8 9.2 9.1 12.9 7.7 9.2 15.0 7.7 25.6 14.0 10.7 10.0 14.0 9.0 19.6 13.1 17.9 37.0 15.2 11.8 20.3 23.2 9.2 23.5 17.1 13.0 26.6 5.6 14.0 20.3 9.2 23.1 36.6 8.1 13.1 17.3 14.3 8.5 25.8 14.8 10.4 16.9 26.3 9.6 10.6 14.9 15.7 8.9 6.7 29.8 10.7 14.6 10.0 6.5 SLC41A3 FLJ20473 ENSG00000114544 "Solute carrier family 41 member 3" Q96GZ6 3 126006357-126101561 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045847 Approved Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA045847: AB_2679472" "unprognostic (1.77e-1)" "unprognostic (3.35e-2)" "unprognostic (1.11e-1)" "unprognostic (3.37e-2)" "unprognostic (7.68e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.36e-1)" "unprognostic (3.23e-2)" "unprognostic (2.82e-3)" "unprognostic (5.74e-2)" "unprognostic (3.57e-1)" "prognostic favorable (6.04e-7)" "unprognostic (1.26e-1)" "unprognostic (5.88e-2)" "unprognostic (2.85e-1)" "unprognostic (7.54e-2)" 29.5 47.2 53.3 13.3 55.6 11.3 29.5 55.0 56.1 42.4 53.0 24.8 18.1 44.4 55.1 22.2 40.2 28.6 34.3 57.7 54.9 27.7 14.3 21.4 18.1 56.8 54.0 54.5 32.7 34.9 40.0 19.7 59.6 23.1 19.2 25.7 31.1 23.7 61.8 24.6 23.8 29.4 49.8 19.6 27.8 44.7 54.7 34.4 32.0 47.9 19.3 28.9 29.6 48.4 43.7 17.4 28.5 24.1 78.7 45.3 42.4 24.4 42.1 32.9 39.0 23.3 38.7 31.4 44.8 48.9 35.7 33.3 10.8 42.1 29.0 31.1 32.0 17.2 32.1 34.2 65.3 31.4 18.4 44.0 50.8 20.0 41.1 48.7 46.5 38.2 14.7 26.2 44.0 22.2 35.1 25.7 21.7 57.4 26.3 18.6 29.3 43.5 39.6 31.6 22.1 23.8 37.8 12.3 104.0 26.6 12.2 41.9 32.2 30.8 23.2 47.1 28.0 19.4 17.2 15.8 27.7 14.0 28.9 13.0 6.3 4.6 12.0 9.4 9.6 9.4 11.1 12.2 9.8 9.0 9.6 9.1 1.2 14.9 6.1 9.6 21.8 6.1 53.3 55.6 55.0 56.1 57.7 54.9 56.8 54.0 59.6 49.8 54.7 48.4 25.6 16.0 10.9 9.8 13.5 13.8 22.3 24.9 20.5 15.4 22.9 23.5 14.4 32.9 20.5 22.0 4.2 34.6 14.6 7.5 3.9 35.8 36.7 34.1 15.3 28.5 21.1 5.0 17.0 24.7 36.1 19.7 11.7 17.9 5.7 21.2 35.0 7.2 16.1 28.6 20.7 12.1 30.5 12.8 10.3 14.7 37.6 8.6 14.2 15.0 13.5 25.9 7.2 11.6 8.0 24.3 6.8 54.9 10.3 15.3 14.7 12.6 14.8 12.1 26.3 23.1 20.7 16.7 45.4 18.2 15.3 25.3 17.7 42.4 15.6 19.0 SLC45A2 "AIM-1, MATP, OCA4" ENSG00000164175 "Solute carrier family 45 member 2" Q9UMX9 5 33944623-33984693 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Melanin biosynthesis, Sensory transduction, Vision" "Albinism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 1.2;skin 1: 1.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Early spermatids: 3.1;Excitatory neurons: 4.1;Inhibitory neurons: 5.4;Late spermatids: 5.1;Melanocytes: 12.4;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 4.7" "Cancer enriched" "Detected in some" 18 "melanoma: 47.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 28 "SK-MEL-30: 60.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.97e-1)" "unprognostic (3.99e-2)" "unprognostic (3.55e-1)" "unprognostic (2.39e-2)" "unprognostic (2.36e-2)" "unprognostic (1.09e-1)" "unprognostic (8.45e-2)" "unprognostic (5.34e-3)" "unprognostic (4.06e-2)" "unprognostic (8.45e-2)" "unprognostic (7.39e-4)" "unprognostic (1.40e-2)" "unprognostic (1.84e-3)" "unprognostic (1.55e-1)" "unprognostic (1.50e-3)" "unprognostic (2.48e-2)" "unprognostic (3.39e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.4 1.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.4 0.0 0.0 0.1 1.0 0.0 0.0 0.1 0.0 0.2 1.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 60.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.3 0.1 0.1 0.2 0.1 0.2 0.4 0.1 0.0 0.0 1.0 0.0 0.6 0.1 0.0 0.0 0.6 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.1 0.3 0.1 0.3 0.0 0.0 4.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.4 5.1 0.0 0.0 12.4 0.0 0.0 0.1 0.0 2.5 4.7 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.1 0.1 0.0 SLC5A4 "DJ90G24.4, SAAT1, SGLT3" ENSG00000100191 "Solute carrier family 5 member 4" Q9NY91 22 32218464-32255347 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 19.8" "Group enriched" "Detected in some" 11 "Excitatory neurons: 28.1;Inhibitory neurons: 20.5;Microglial cells: 31.9;Oligodendrocyte precursor cells: 9.5" "Cancer enriched" "Detected in some" 10 "melanoma: 7.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "SK-MEL-30: 27.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.93e-1)" "unprognostic (1.57e-1)" "unprognostic (3.10e-3)" "unprognostic (1.63e-2)" "unprognostic (1.28e-2)" "unprognostic (2.85e-3)" "unprognostic (2.97e-2)" "unprognostic (3.80e-2)" "unprognostic (3.58e-2)" "unprognostic (1.06e-1)" "unprognostic (2.65e-3)" "unprognostic (4.50e-1)" "unprognostic (1.99e-5)" "unprognostic (2.34e-1)" "unprognostic (1.63e-1)" "unprognostic (2.28e-1)" "unprognostic (2.69e-1)" 0.7 0.2 0.1 0.1 0.1 0.1 0.8 0.4 2.9 1.2 0.0 0.1 17.6 0.8 0.3 0.2 0.7 0.6 0.6 0.6 0.0 0.7 0.2 1.5 0.2 2.1 0.0 0.3 0.4 0.3 0.1 0.0 2.7 0.5 0.1 0.1 0.2 0.3 0.1 0.3 19.8 1.4 0.0 0.3 0.2 0.4 0.3 0.0 1.3 0.0 0.1 0.4 0.7 0.7 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 27.8 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 2.9 0.6 0.0 2.1 0.0 2.7 0.0 0.3 0.7 0.9 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 28.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 31.9 0.1 0.0 0.0 9.5 1.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC6A17 ENSG00000197106 "Solute carrier family 6 member 17" Q9H1V8 1 110150494-110202202 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 52.9;pituitary gland: 25.3" "Group enriched" "Detected in some" 5 "Excitatory neurons: 60.6;Inhibitory neurons: 59.4" "Cancer enriched" "Detected in some" 9 "melanoma: 17.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-MEL-30: 36.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008043, HPA008044" Enhanced Approved Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA008043: , HPA008044: AB_1857192" "unprognostic (1.13e-1)" "unprognostic (1.37e-3)" "unprognostic (5.52e-3)" "unprognostic (3.00e-2)" "unprognostic (1.17e-1)" "unprognostic (4.88e-2)" "unprognostic (6.11e-3)" "unprognostic (3.87e-3)" "unprognostic (1.70e-2)" "unprognostic (1.80e-1)" "unprognostic (1.68e-2)" "unprognostic (2.94e-1)" "unprognostic (1.89e-2)" "unprognostic (1.73e-2)" "unprognostic (9.76e-2)" "unprognostic (1.38e-3)" "unprognostic (1.68e-3)" 0.4 5.9 21.6 0.2 26.3 0.1 0.3 1.2 52.9 0.1 0.0 0.3 0.0 0.1 1.0 0.4 0.1 0.1 0.1 20.1 9.6 1.3 0.0 0.1 0.0 13.7 8.2 0.0 1.4 8.8 25.3 0.8 10.5 0.1 0.1 6.0 0.6 0.1 0.1 6.2 0.1 0.1 0.0 0.0 0.7 1.8 24.8 0.0 0.3 0.1 0.0 0.1 0.1 15.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 5.5 0.5 2.1 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 1.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.8 6.2 1.9 36.0 1.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 7.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 26.3 1.2 52.9 20.1 9.6 13.7 8.2 10.5 0.0 24.8 15.7 0.0 0.0 0.0 2.6 0.0 0.5 0.0 0.1 0.0 5.1 0.2 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 1.2 0.0 0.0 0.5 0.0 0.0 60.6 0.0 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 59.4 0.0 4.1 0.0 0.0 0.7 0.0 0.0 10.6 3.7 0.0 0.7 0.0 4.5 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 0.7 0.4 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 0.0 SMIM26 "LINC00493, LOC388789" ENSG00000232388 "Small integral membrane protein 26" A0A096LP01 20 18567347-18569563 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 252.6;Breast myoepithelial cells: 317.5;Distal tubular cells: 389.4;Proximal tubular cells: 588.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068733 Approved Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA068733: AB_2686024" "unprognostic (1.20e-2)" "unprognostic (5.85e-2)" "unprognostic (2.83e-1)" "unprognostic (8.06e-2)" "unprognostic (2.68e-1)" "unprognostic (1.65e-1)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.67e-3)" "unprognostic (2.16e-1)" "unprognostic (2.68e-2)" "unprognostic (2.40e-2)" "unprognostic (2.02e-1)" "unprognostic (3.18e-1)" "prognostic favorable (7.84e-5)" 76.0 104.3 92.2 43.6 96.2 83.4 107.0 102.7 123.1 72.8 103.9 89.8 63.2 67.2 134.8 71.0 78.9 67.9 136.4 93.6 97.0 96.1 117.7 53.7 72.6 94.8 93.6 113.0 103.4 99.4 90.7 51.3 96.9 71.3 69.8 63.1 91.1 61.9 243.1 69.2 65.8 56.5 96.2 57.8 98.5 37.6 94.4 88.7 85.2 213.5 73.6 79.7 63.6 103.4 99.3 129.1 94.3 98.0 85.9 116.0 110.8 72.3 86.5 83.4 95.2 80.9 113.0 99.4 81.1 79.7 149.1 106.8 90.4 120.2 95.9 42.5 112.9 131.7 59.4 270.2 162.4 86.6 96.5 100.0 159.4 94.6 152.2 144.7 128.1 120.8 98.5 89.3 105.4 125.0 104.0 240.4 53.8 188.5 153.6 67.4 110.0 136.8 192.0 100.4 92.8 98.1 77.2 145.6 297.5 82.9 106.8 126.0 65.8 58.1 60.8 71.7 76.6 85.0 229.8 113.7 52.2 56.2 44.4 142.4 133.5 108.6 96.5 116.6 102.8 155.6 131.7 112.3 164.5 145.7 145.0 139.2 241.3 99.5 112.8 157.7 150.0 130.5 92.2 96.2 102.7 123.1 93.6 97.0 94.8 93.6 96.9 96.2 94.4 103.4 83.8 128.2 83.8 0.0 44.4 0.0 0.0 0.0 0.0 0.0 252.6 317.5 0.0 0.0 35.9 171.0 0.0 205.5 62.6 0.0 389.4 146.2 0.0 185.2 95.5 36.4 0.0 0.0 0.0 214.3 137.9 57.8 0.0 118.7 35.3 100.5 0.0 0.0 188.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.3 0.0 0.0 66.2 0.0 0.0 0.0 0.0 187.7 0.0 0.0 12.1 0.0 0.0 588.2 87.5 0.0 0.0 0.0 45.9 0.0 0.0 0.0 0.0 208.0 37.2 108.8 0.0 0.0 SNIP1 PML1 ENSG00000163877 "Smad nuclear interacting protein 1" Q8TAD8 1 37534449-37554293 "Disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, RNA-mediated gene silencing" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036896 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA036896: AB_10670244" "unprognostic (1.37e-1)" "unprognostic (2.83e-1)" "unprognostic (1.65e-3)" "unprognostic (7.24e-2)" "unprognostic (5.83e-2)" "unprognostic (8.30e-3)" "unprognostic (3.26e-2)" "unprognostic (3.66e-2)" "unprognostic (7.74e-2)" "unprognostic (5.01e-2)" "unprognostic (9.30e-2)" "unprognostic (5.34e-3)" "unprognostic (3.06e-2)" "unprognostic (6.78e-3)" "unprognostic (2.63e-2)" "unprognostic (1.63e-1)" "unprognostic (1.86e-1)" 3.2 3.8 3.5 2.8 3.5 5.5 4.3 4.4 4.4 3.5 3.6 3.3 2.5 3.7 3.2 3.9 2.7 2.3 3.1 3.7 3.9 2.8 6.3 2.7 3.7 3.5 3.5 3.5 3.4 3.9 3.1 2.4 3.5 3.8 2.5 3.9 3.4 3.1 3.1 3.4 3.5 2.8 3.2 3.9 3.6 4.4 3.8 4.1 2.9 3.2 4.2 3.1 3.0 4.0 4.9 2.6 5.2 5.1 6.2 5.9 3.5 6.2 6.9 5.7 5.0 2.6 4.1 6.6 4.6 6.5 3.7 5.0 4.9 5.6 4.7 6.0 7.0 10.3 4.4 5.3 7.0 9.6 5.5 5.6 6.5 5.7 7.2 6.2 5.6 5.0 7.3 5.7 4.1 3.5 5.7 7.3 8.5 4.0 6.1 5.0 8.8 5.6 4.3 4.6 4.1 8.4 6.4 4.1 8.3 5.4 3.6 5.1 9.2 4.3 4.9 5.6 6.0 7.0 8.8 5.3 5.3 6.7 4.1 1.5 0.9 1.3 1.5 0.8 1.5 1.0 1.0 1.5 0.8 0.9 1.4 1.2 1.4 1.0 1.2 1.3 1.3 0.6 3.5 3.5 4.4 4.4 3.7 3.9 3.5 3.5 3.5 3.2 3.8 4.0 14.4 19.2 11.9 3.9 18.5 16.2 11.8 6.9 22.8 10.6 18.0 12.1 6.1 17.2 13.9 5.5 8.4 5.4 20.7 11.8 1.9 7.3 7.5 34.4 25.8 9.2 8.4 7.2 6.5 7.1 4.7 12.4 13.7 58.1 12.0 11.0 11.7 10.9 4.6 10.1 6.1 11.0 10.2 8.8 9.2 11.7 8.1 11.4 8.8 4.7 9.5 9.9 12.3 7.1 6.8 8.4 5.8 7.9 15.7 9.7 6.0 4.4 9.7 16.6 0.0 13.6 11.1 14.4 15.1 19.5 18.0 10.1 16.9 8.0 6.5 12.6 SNRPB2 "Msl1, U2B''" ENSG00000125870 "Small nuclear ribonucleoprotein polypeptide B2" P08579 20 16729961-16742564 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 524.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 381.4;SK-MEL-30: 378.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050814, HPA076104" Supported Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "Cytoplasmic bodies" "HPA050814: AB_2681245, HPA076104: AB_2732301" "unprognostic (4.73e-2)" "unprognostic (1.78e-1)" "unprognostic (4.02e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (8.45e-2)" "unprognostic (8.36e-2)" "prognostic unfavorable (6.03e-7)" "unprognostic (4.23e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.06e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.14e-2)" "unprognostic (1.77e-1)" 27.5 27.6 23.9 30.9 24.9 53.9 31.0 24.3 35.7 22.3 26.0 26.4 24.3 29.0 35.2 20.8 24.4 21.9 25.0 24.9 25.9 42.3 30.1 22.2 43.3 24.9 25.2 29.1 18.3 26.9 22.6 28.7 24.7 21.9 26.5 11.2 21.1 21.6 30.2 17.0 24.6 27.1 25.6 28.4 23.4 22.6 24.7 37.3 25.6 27.2 36.6 28.9 19.8 27.3 76.0 73.3 94.3 59.1 46.1 57.8 104.7 73.4 60.9 78.0 76.1 84.6 83.5 121.0 56.0 63.0 119.2 69.3 74.9 85.5 111.0 40.0 62.8 111.8 22.4 157.4 53.9 132.0 73.8 57.6 56.0 71.5 55.6 58.1 74.4 81.3 93.8 53.6 80.6 79.2 152.5 159.6 84.2 381.4 97.0 86.1 113.1 84.9 76.9 50.8 49.8 142.3 54.5 147.6 378.7 69.4 93.8 106.5 63.7 71.0 71.2 64.4 122.7 46.9 102.8 134.7 33.7 77.8 157.1 51.8 29.4 47.4 27.3 38.6 35.8 31.5 34.7 31.5 31.6 29.1 30.0 33.4 12.8 31.7 40.5 45.9 48.0 29.9 23.9 24.9 24.3 35.7 24.9 25.9 24.9 25.2 24.7 25.6 24.7 27.3 125.9 44.8 58.0 6.2 128.6 89.1 186.9 238.2 60.3 30.7 93.8 118.5 67.4 107.2 126.5 93.8 0.0 281.4 150.1 79.6 215.2 165.9 163.3 105.3 150.3 124.6 93.3 131.7 12.9 169.2 288.3 120.8 50.0 120.5 132.5 103.2 140.3 139.3 227.3 48.8 14.3 133.3 152.5 157.9 124.6 35.1 172.7 120.5 110.3 8.4 195.4 77.7 153.5 15.1 21.5 169.4 102.7 155.7 91.2 143.8 94.9 524.6 107.2 25.1 98.6 118.7 147.5 192.4 130.4 60.8 96.0 376.9 150.1 94.7 127.7 170.2 SORT1 "Gp95, NT3" ENSG00000134243 "Sortilin 1" Q99523 1 109309568-109397918 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Osteogenesis, Transport" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 285.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 447.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 9.2;non-classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006889, CAB011498" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 7170000 110000 "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB011498: AB_2192606, HPA006889: AB_1080056" "unprognostic (2.10e-2)" "unprognostic (7.46e-2)" "prognostic favorable (7.74e-6)" "unprognostic (4.12e-1)" "unprognostic (9.41e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (3.34e-3)" "unprognostic (4.27e-2)" "unprognostic (9.44e-2)" "unprognostic (2.42e-2)" "unprognostic (1.28e-2)" "unprognostic (1.23e-3)" "unprognostic (1.45e-2)" "unprognostic (2.15e-1)" "unprognostic (3.95e-1)" "unprognostic (4.46e-3)" 48.2 11.3 71.0 12.0 168.3 21.4 25.1 124.3 114.2 17.7 21.5 29.5 22.1 24.7 139.8 41.5 27.5 17.8 64.7 131.8 90.0 38.7 6.5 37.4 2.8 151.9 133.8 6.1 17.5 46.5 11.3 44.8 153.1 18.3 26.9 40.0 25.2 44.0 85.0 19.0 21.9 27.8 102.8 10.2 18.2 43.5 118.0 6.4 42.7 71.8 10.3 16.9 18.0 285.6 38.8 15.3 37.5 45.8 107.0 21.2 107.3 28.2 44.9 27.2 29.0 39.8 14.0 0.3 35.2 11.9 19.9 9.4 44.7 22.3 38.9 1.1 21.2 10.7 23.5 43.1 41.8 0.2 33.5 53.2 3.6 33.3 7.3 72.6 4.2 31.7 81.3 4.0 38.7 41.1 27.9 0.8 14.1 17.5 6.3 30.7 87.9 18.9 52.0 27.8 38.3 21.8 16.6 109.3 120.6 53.1 46.1 6.7 1.1 5.8 21.7 1.0 47.6 37.0 32.2 0.3 9.8 0.3 24.3 0.0 7.1 2.5 0.0 9.2 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 1.8 0.4 10.8 1.6 0.0 2.0 71.0 168.3 124.3 114.2 131.8 90.0 151.9 133.8 153.1 102.8 118.0 285.6 10.6 38.5 47.9 54.5 1.9 1.3 4.7 6.7 1.2 14.9 27.5 14.2 98.9 27.1 20.3 75.4 35.5 30.6 3.2 70.2 5.9 23.9 65.1 33.2 5.2 15.9 16.8 4.0 87.9 23.7 30.2 9.8 16.8 34.9 7.6 10.4 7.9 22.1 30.1 13.5 56.7 27.7 6.1 38.7 9.9 79.7 8.7 34.6 21.4 78.7 37.7 21.7 0.0 48.7 447.8 25.6 23.2 49.7 1.5 7.1 64.0 13.1 29.6 50.7 32.9 25.1 53.6 46.3 21.6 9.3 1.8 36.8 2.1 1.8 28.3 10.8 SPATS1 "FLJ25442, SPATA8, SRSP1" ENSG00000249481 "Spermatogenesis associated serine rich 1" Q496A3 6 44342650-44380179 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 5.9;fallopian tube: 7.6;testis: 22.1" "Group enriched" "Detected in some" 13 "Early spermatids: 30.9;Late spermatids: 12.1;Respiratory ciliated cells: 9.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "SK-MEL-30: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030897, HPA049722" Approved Approved Nucleoplasm NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA030897: AB_2673647, HPA049722: AB_2680861" "unprognostic (2.30e-3)" 0.0 0.1 0.7 0.0 0.7 0.2 0.0 0.6 0.8 0.2 0.7 0.0 0.0 0.2 5.9 0.0 7.6 0.0 0.1 0.8 0.8 0.0 0.0 0.6 0.1 1.4 2.1 0.0 0.1 0.1 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 1.3 0.0 0.1 22.1 0.7 0.1 0.1 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.3 0.1 0.1 0.0 0.1 0.3 0.0 0.1 0.4 0.1 0.0 0.1 7.9 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.7 0.7 0.6 0.8 0.8 0.8 1.4 2.1 1.2 1.3 0.7 1.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.9 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPCS2 KIAA0102 ENSG00000118363 "Signal peptidase complex subunit 2" Q15005 11 74949247-74979033 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 933.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013386 Approved Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA013386: AB_1857426" "unprognostic (2.43e-1)" "unprognostic (7.01e-2)" "unprognostic (1.65e-2)" "unprognostic (7.09e-3)" "unprognostic (9.30e-2)" "unprognostic (2.31e-2)" "unprognostic (7.04e-3)" "unprognostic (9.61e-2)" "unprognostic (8.83e-2)" "unprognostic (2.02e-3)" "unprognostic (1.25e-2)" "unprognostic (1.74e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (5.70e-2)" "unprognostic (1.37e-1)" "unprognostic (8.62e-2)" 81.0 99.4 86.4 104.9 96.6 60.1 108.2 98.7 131.1 127.5 88.8 119.3 90.5 92.2 220.1 72.8 95.9 66.5 76.2 86.3 102.7 105.6 151.6 79.5 98.2 98.5 93.3 84.3 137.3 147.7 75.1 81.2 98.9 106.9 115.1 75.4 139.0 93.3 71.4 56.6 83.3 93.1 99.7 92.5 105.5 50.4 94.3 97.8 143.9 69.5 154.8 95.0 68.1 107.7 141.7 163.4 213.2 192.2 183.2 122.0 115.9 198.6 192.4 179.0 154.8 322.9 311.7 228.2 244.1 168.9 213.6 254.2 187.3 146.1 220.5 190.0 136.4 232.2 189.7 268.9 208.1 249.3 156.7 109.7 186.1 151.5 245.5 156.8 173.7 166.6 271.9 578.0 163.9 215.0 179.1 158.0 131.0 558.3 153.5 219.2 328.2 522.4 208.2 232.3 172.3 172.6 198.1 262.9 687.6 146.7 254.1 187.6 142.0 201.9 124.9 212.1 177.5 245.1 268.8 423.8 83.0 173.4 209.4 546.3 229.2 219.2 279.8 231.0 315.2 400.7 253.7 269.4 222.0 344.3 191.7 229.5 148.5 260.9 209.8 459.5 272.0 428.3 86.4 96.6 98.7 131.1 86.3 102.7 98.5 93.3 98.9 99.7 94.3 107.7 192.3 86.6 143.6 40.5 323.2 304.5 314.0 812.0 129.7 97.6 212.6 199.9 69.1 214.4 406.0 239.1 52.1 330.8 233.5 130.3 189.8 290.0 36.5 126.4 250.4 181.4 125.4 191.5 46.6 288.0 334.4 239.4 104.5 240.2 155.2 114.7 158.1 338.0 278.9 95.9 55.4 255.1 431.3 140.1 283.3 27.2 240.8 159.7 521.2 23.4 188.6 215.6 197.8 48.7 73.5 253.2 140.0 195.6 933.5 355.5 141.7 280.8 231.1 87.3 170.9 153.6 253.6 127.8 133.1 112.1 229.4 464.8 204.6 192.2 189.5 298.1 SPSB1 SSB-1 ENSG00000171621 "SplA/ryanodine receptor domain and SOCS box containing 1" Q96BD6 1 9292894-9369532 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 79.5;Proximal enterocytes: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 81.5;SK-MEL-30: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.23e-2)" "unprognostic (8.91e-2)" "unprognostic (1.56e-1)" "unprognostic (2.85e-1)" "unprognostic (4.18e-2)" "unprognostic (2.88e-1)" "unprognostic (2.02e-2)" "unprognostic (1.24e-1)" "unprognostic (3.84e-2)" "unprognostic (2.54e-2)" "unprognostic (6.86e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.08e-6)" "unprognostic (3.95e-2)" "unprognostic (3.49e-1)" "unprognostic (1.35e-2)" "unprognostic (2.24e-2)" 53.3 9.7 7.8 14.4 14.2 1.4 25.1 12.9 10.2 30.7 5.1 23.3 19.6 47.0 3.8 26.7 23.4 29.1 20.1 9.4 10.9 16.9 48.1 28.7 9.3 22.8 15.0 24.1 30.6 20.4 10.2 10.7 15.4 18.1 8.7 2.0 15.7 10.0 44.2 25.3 30.0 26.1 12.1 3.6 17.9 8.3 15.5 10.3 20.3 32.3 12.1 33.0 21.7 19.7 16.2 14.6 1.1 3.2 42.4 20.2 26.6 10.7 35.4 21.0 16.6 15.8 23.2 0.4 21.5 16.4 25.0 23.9 4.8 19.4 13.8 58.2 3.8 0.0 19.6 17.5 27.1 0.1 1.4 21.1 38.3 81.5 10.4 20.8 30.9 3.2 1.9 42.1 17.3 6.0 9.0 0.6 2.3 11.1 15.5 3.1 6.4 5.1 17.9 10.9 3.9 1.1 17.1 45.8 71.4 28.4 1.2 5.3 25.8 15.2 18.9 24.0 9.9 17.7 27.3 5.6 27.5 2.0 16.7 1.2 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.1 0.0 0.1 0.1 0.2 0.0 0.3 0.0 0.0 0.8 0.2 7.8 14.2 12.9 10.2 9.4 10.9 22.8 15.0 15.4 12.1 15.5 19.7 19.4 19.2 5.3 2.6 6.5 69.0 47.0 11.8 25.6 0.6 26.9 17.8 4.1 24.3 11.5 3.7 2.1 1.1 3.2 19.9 3.9 25.0 0.8 42.2 30.3 20.6 6.6 0.4 2.1 32.0 12.0 67.0 4.1 79.5 14.0 30.7 13.2 21.6 3.1 11.8 1.7 7.7 2.0 0.9 27.7 1.8 11.8 8.2 49.8 3.7 3.3 2.2 0.0 18.1 22.8 33.7 15.6 8.2 8.4 28.4 83.1 5.5 20.7 0.6 6.6 40.7 22.9 0.4 3.2 57.0 70.8 2.2 8.1 0.5 11.4 63.1 SPSB3 "C16orf31, SSB-3" ENSG00000162032 "SplA/ryanodine receptor domain and SOCS box containing 3" Q6PJ21 16 1776712-1793700 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046602 Uncertain Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA046602: AB_2679717" "unprognostic (1.18e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-1)" "unprognostic (1.15e-3)" "unprognostic (1.82e-1)" "unprognostic (8.91e-4)" "unprognostic (1.07e-2)" "unprognostic (8.31e-2)" "unprognostic (5.65e-2)" "unprognostic (8.43e-2)" "unprognostic (3.41e-2)" "unprognostic (4.83e-2)" "unprognostic (5.25e-7)" "unprognostic (2.16e-2)" "unprognostic (2.02e-1)" "unprognostic (3.77e-1)" "unprognostic (4.72e-4)" 27.1 44.7 27.9 7.7 28.5 21.2 25.8 37.0 40.2 27.1 24.0 28.9 14.7 21.3 3.3 36.1 23.7 10.0 28.6 26.4 27.2 24.3 41.8 20.6 12.4 29.7 28.3 37.1 44.0 11.4 15.3 10.3 27.4 23.3 5.1 9.6 26.4 15.5 88.5 48.4 18.8 5.6 28.3 23.3 27.8 17.3 29.2 26.1 19.7 31.0 7.8 23.2 28.7 31.8 7.3 9.1 9.7 13.4 13.6 12.5 19.8 10.6 11.0 11.5 12.6 8.4 20.0 3.2 17.4 6.0 4.5 13.9 4.8 10.9 1.8 14.7 15.0 5.2 13.9 10.4 20.2 4.5 12.0 11.3 26.8 7.2 8.4 17.1 17.5 22.1 7.8 15.4 5.4 24.0 16.3 16.0 8.1 10.8 7.1 29.7 5.9 26.7 10.6 1.3 12.9 16.6 12.6 27.8 29.4 6.9 16.1 18.0 16.1 5.6 10.6 10.5 5.5 26.1 28.2 8.9 5.4 8.9 5.9 112.3 44.8 83.4 67.9 41.8 81.2 46.8 63.1 61.7 42.3 44.2 43.6 46.6 91.5 45.7 37.2 42.8 100.7 48.4 27.9 28.5 37.0 40.2 26.4 27.2 29.7 28.3 27.4 28.3 29.2 31.8 74.2 38.5 32.1 29.7 56.1 98.4 53.3 72.7 60.3 74.1 64.1 83.7 0.2 40.0 54.9 55.2 39.6 63.0 104.2 68.6 52.8 50.8 46.7 29.4 32.3 46.1 48.7 50.5 18.2 47.6 74.8 42.8 65.2 37.8 35.4 76.2 57.1 62.5 31.8 90.9 19.4 57.8 38.7 42.7 72.2 91.6 77.0 44.8 76.5 24.4 61.6 76.0 99.9 24.6 30.7 45.3 83.2 74.9 61.2 50.5 96.3 50.6 37.2 89.8 39.5 34.0 45.3 23.8 39.7 37.0 128.3 64.4 87.8 33.2 52.7 54.3 SSU72 HSPC182 ENSG00000160075 "SSU72 homolog, RNA polymerase II CTD phosphatase" Q9NP77 1 1541673-1574863 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA processing" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 700.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069290, HPA070604" Supported Approved Nucleoplasm,Cytosol No No "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA069290: AB_2686108, HPA070604: AB_2686285" "unprognostic (3.33e-2)" "unprognostic (2.79e-2)" "unprognostic (6.37e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "unprognostic (9.84e-2)" "unprognostic (2.40e-3)" "unprognostic (2.43e-2)" "unprognostic (3.23e-1)" "unprognostic (3.23e-1)" "unprognostic (6.75e-2)" "unprognostic (1.36e-1)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "unprognostic (8.51e-2)" "unprognostic (3.77e-1)" "unprognostic (1.06e-1)" 105.4 77.3 101.9 64.1 107.4 61.0 94.8 101.9 119.7 82.1 112.6 95.9 75.1 80.4 88.3 123.3 80.6 52.7 131.5 106.2 113.3 105.5 122.4 87.9 74.3 106.6 106.6 81.9 115.0 63.4 99.9 52.0 109.0 86.8 62.7 52.1 100.6 53.6 246.7 100.2 90.8 53.8 103.4 105.9 96.1 58.9 113.2 65.1 107.8 136.3 67.7 83.6 87.2 103.9 204.6 127.6 90.2 140.3 152.1 145.4 92.2 172.8 134.1 147.6 152.5 120.8 229.7 205.4 92.1 137.0 143.7 155.0 147.4 142.5 142.8 172.8 173.9 129.3 110.7 193.8 171.5 165.6 108.4 130.7 117.8 158.4 149.8 123.2 140.1 122.6 227.9 154.1 118.6 181.4 190.8 264.5 158.5 198.9 191.5 149.5 145.5 289.8 163.7 61.8 166.1 114.0 117.1 296.3 535.3 152.0 154.6 142.0 107.8 140.8 89.2 160.9 150.7 186.5 241.2 258.1 148.0 260.1 69.9 143.4 93.0 188.6 80.0 98.9 99.3 120.7 105.9 95.9 100.2 117.7 127.6 105.1 204.1 75.3 91.7 62.9 161.5 101.0 101.9 107.4 101.9 119.7 106.2 113.3 106.6 106.6 109.0 103.4 113.2 103.9 107.5 28.9 72.7 14.7 130.6 186.2 138.9 100.0 108.1 95.9 169.6 173.7 92.4 151.5 69.2 101.2 20.9 208.6 129.9 171.2 291.6 76.3 283.0 107.8 77.6 91.5 142.0 78.8 23.3 106.6 239.4 84.4 89.7 101.0 61.5 90.6 98.6 132.7 141.1 112.7 23.8 165.8 83.4 178.4 130.0 700.2 104.7 123.3 167.2 15.9 144.8 152.3 193.6 25.6 20.1 91.9 206.7 85.7 132.5 199.6 242.8 325.8 59.0 73.4 59.2 77.6 136.6 97.1 157.4 155.9 220.4 245.3 128.1 86.2 172.1 153.2 ST20 HCCS-1 ENSG00000180953 "Suppressor of tumorigenicity 20" Q9HBF5 15 79898840-79923702 "Metabolic proteins, Predicted intracellular proteins" "Tumor suppressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 51.3;monocytes: 84.8;Proximal tubular cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "eosinophil: 88.6;neutrophil: 313.4" "Lineage enriched" "Detected in all" 11 "granulocytes: 313.4" "Cell line enhanced" "Detected in many" "SK-MEL-30: 54.6" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 3: Monocytes - Immune response regulation" "unprognostic (2.48e-1)" "unprognostic (1.28e-1)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (2.04e-2)" "unprognostic (3.20e-1)" "unprognostic (1.39e-1)" "unprognostic (3.86e-1)" "unprognostic (1.35e-3)" "unprognostic (4.21e-2)" "unprognostic (3.03e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (7.69e-8)" "unprognostic (6.49e-2)" "unprognostic (2.61e-2)" "unprognostic (9.88e-2)" "unprognostic (4.19e-2)" 8.1 5.4 9.3 7.0 9.0 4.8 7.5 11.3 12.4 8.2 8.0 7.5 2.0 5.2 8.3 6.3 7.9 2.8 9.4 8.9 10.0 11.6 23.8 10.4 7.6 8.6 8.7 7.0 6.5 4.9 11.2 3.2 9.6 11.0 2.7 8.9 6.0 3.4 4.1 6.8 10.0 2.7 8.2 24.1 5.6 11.0 9.7 6.2 10.5 4.9 5.6 7.8 5.8 9.0 8.6 17.6 7.7 9.3 12.9 10.9 16.2 8.7 5.8 4.5 5.8 3.8 13.7 10.4 5.5 6.5 14.8 14.0 16.2 5.0 3.3 14.8 13.6 12.1 13.5 5.4 11.6 4.6 6.8 12.1 6.4 3.2 9.2 12.4 5.0 19.6 10.1 6.1 7.1 26.4 6.2 31.6 17.8 26.8 11.6 9.1 2.5 5.5 11.4 7.2 11.0 11.9 16.2 10.8 54.6 19.8 9.0 29.4 6.0 11.4 2.9 0.0 7.3 6.6 37.4 16.5 8.8 25.3 5.9 2.2 17.5 88.6 8.0 10.9 6.8 17.1 9.1 8.9 14.1 17.0 8.5 7.8 313.4 18.8 27.8 8.0 8.8 11.0 9.3 9.0 11.3 12.4 8.9 10.0 8.6 8.7 9.6 8.2 9.7 9.0 2.7 6.4 17.9 0.0 6.1 4.8 6.8 17.5 1.2 8.6 16.5 22.1 13.5 7.2 11.8 14.7 8.4 12.2 5.6 12.1 23.5 17.0 17.1 6.9 6.5 5.2 19.3 4.0 0.0 11.9 9.9 5.9 4.1 10.0 7.0 10.2 6.1 51.3 40.0 1.7 0.0 11.7 16.2 8.8 8.1 6.4 7.2 17.7 5.4 0.0 84.8 14.8 2.1 0.0 0.0 15.9 23.2 4.9 1.6 10.9 23.9 52.3 9.8 5.9 6.6 4.4 6.2 23.4 23.5 3.2 4.3 43.1 6.0 6.5 10.7 6.6 ST20-MTHFS ENSG00000259332 "ST20-MTHFS readthrough" 15 79845150-79923754 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.8;Collecting duct cells: 1.8;Erythroid cells: 4.2;Gastric mucus-secreting cells: 5.1;Squamous epithelial cells: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 492.2" "Group enriched" "Detected in all" 4 "granulocytes: 492.2;monocytes: 133.6" "Low cell line specificity" "Detected in all" HPA008067 Uncertain NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" "HPA008067: AB_1078882" "unprognostic (9.84e-2)" "unprognostic (1.74e-2)" "unprognostic (2.06e-2)" "unprognostic (4.41e-2)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "unprognostic (3.75e-3)" "unprognostic (6.63e-3)" "unprognostic (1.02e-1)" "unprognostic (8.19e-4)" "unprognostic (2.38e-1)" "unprognostic (5.26e-2)" "unprognostic (1.26e-1)" "unprognostic (6.53e-2)" "unprognostic (1.28e-1)" "unprognostic (2.04e-1)" 9.9 10.2 7.3 15.2 7.5 10.1 7.8 8.2 12.0 8.5 8.9 9.5 10.9 6.7 10.0 3.8 7.3 7.7 6.5 8.1 8.4 38.6 96.6 11.0 11.8 8.2 8.8 6.0 15.0 24.0 2.4 9.7 8.4 15.5 8.7 12.2 12.8 8.5 10.5 3.8 14.6 7.5 7.4 7.7 12.0 7.6 9.1 10.3 11.1 10.1 12.8 7.2 1.5 9.1 16.2 33.1 6.6 6.5 24.0 14.2 19.1 13.9 22.1 27.4 24.6 15.7 35.9 20.1 29.6 13.1 25.6 29.7 44.2 13.6 17.3 24.8 14.6 20.5 20.4 24.3 25.2 10.5 3.7 21.1 32.2 8.1 27.0 19.5 7.9 26.7 37.6 19.7 13.0 20.9 13.7 26.2 16.3 56.3 13.5 20.4 12.4 22.0 32.5 14.8 16.2 9.8 33.3 22.6 40.8 24.3 26.6 21.0 11.4 11.7 19.9 1.2 10.9 10.8 37.0 21.9 6.4 45.4 9.7 76.4 82.3 223.6 38.9 87.1 48.2 53.1 51.3 42.9 50.8 53.7 58.9 51.0 492.2 77.5 133.6 35.5 60.6 75.7 7.3 7.5 8.2 12.0 8.1 8.4 8.2 8.8 8.4 7.4 9.1 9.1 0.0 0.0 0.5 0.0 1.6 0.1 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.0 1.4 1.8 0.0 0.4 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 4.2 0.1 0.0 0.2 0.8 5.1 0.2 0.0 0.1 0.0 1.5 0.3 0.0 0.2 0.2 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.0 1.3 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 4.4 0.3 1.4 1.6 0.0 0.3 0.0 ST3GAL6 "SIAT10, ST3GALVI" ENSG00000064225 "ST3 beta-galactoside alpha-2,3-sialyltransferase 6" Q9Y274 3 98732236-98821201 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 128.8;Hepatocytes: 86.8;Microglial cells: 134.0;Oligodendrocyte precursor cells: 171.4" "Cancer enriched" "Detected in many" 5 "melanoma: 17.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.6;neutrophil: 57.6" "Group enriched" "Detected in many" 143 "dendritic cells: 24.2;granulocytes: 57.6;monocytes: 17.4" "Group enriched" "Detected in many" 4 "RPMI-8226: 96.5;SK-MEL-30: 114.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018792 Approved NA NA 5800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA018792: AB_10964349" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-3)" "unprognostic (4.17e-2)" "unprognostic (5.20e-3)" "unprognostic (3.82e-2)" "unprognostic (1.23e-2)" "unprognostic (2.30e-3)" "unprognostic (2.40e-1)" "unprognostic (2.99e-1)" "unprognostic (2.48e-1)" "unprognostic (4.32e-1)" "unprognostic (3.91e-3)" "unprognostic (6.15e-3)" "unprognostic (9.44e-2)" "unprognostic (9.47e-3)" "unprognostic (6.79e-4)" 14.6 7.9 8.2 3.8 8.9 2.4 6.3 14.0 9.9 4.8 3.0 3.8 2.0 2.2 12.0 1.9 6.3 2.2 26.5 9.3 8.5 14.0 56.0 7.8 1.6 19.5 10.1 1.2 3.5 1.1 4.1 8.5 14.3 3.3 2.7 1.5 19.5 2.0 7.9 16.7 1.9 2.0 14.8 3.2 4.5 1.6 9.2 10.6 2.9 6.4 2.8 1.6 1.4 13.1 0.3 1.3 1.8 2.7 3.3 1.1 12.5 0.4 1.5 1.2 2.2 8.7 0.5 6.4 3.3 0.0 4.6 2.1 3.9 2.0 1.1 0.0 2.7 0.2 0.6 15.1 14.0 13.2 23.7 1.5 0.1 3.5 6.6 22.4 14.2 2.6 0.0 6.3 1.3 0.0 2.1 22.6 3.5 0.0 3.5 1.3 1.5 96.5 3.4 0.0 3.8 19.2 5.1 0.5 114.2 3.6 0.4 23.1 10.8 2.9 2.4 0.8 1.3 24.1 2.0 0.0 4.6 18.6 10.3 18.5 17.4 49.6 0.0 9.6 0.0 0.1 0.0 0.0 24.2 0.0 0.2 0.0 57.6 0.1 4.9 5.5 0.0 4.7 8.2 8.9 14.0 9.9 9.3 8.5 19.5 10.1 14.3 14.8 9.2 13.1 10.1 12.8 35.2 2.3 2.3 11.5 2.6 7.0 2.2 1.2 6.4 5.7 40.4 2.8 2.8 3.7 8.4 45.2 0.0 0.0 13.7 6.8 0.3 128.8 4.2 20.2 16.1 6.6 78.5 2.0 69.5 3.8 9.2 41.0 39.1 1.8 32.5 86.8 34.4 0.0 64.2 0.1 30.5 29.5 64.2 1.0 2.8 38.4 65.8 134.0 38.0 0.9 0.0 171.4 51.6 6.2 0.1 6.8 18.0 5.2 0.0 10.0 27.5 3.5 6.6 1.7 2.2 0.1 1.0 2.1 12.8 27.0 2.0 0.3 0.3 1.8 ST6GALNAC2 "SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM" ENSG00000070731 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2" Q9UJ37 17 76565377-76586956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 10 "Early spermatids: 501.1;Late spermatids: 1763.3" "Cancer enhanced" "Detected in all" "melanoma: 22.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "neutrophil: 47.0" "Lineage enriched" "Detected in many" 16 "granulocytes: 47.0" "Cell line enhanced" "Detected in some" "BEWO: 25.4;HaCaT: 33.8;HBEC3-KT: 28.5;hTCEpi: 73.1;MCF7: 36.4;SK-MEL-30: 112.5;T-47d: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (8.93e-3)" "unprognostic (5.86e-3)" "unprognostic (1.67e-2)" "unprognostic (5.18e-3)" "unprognostic (3.37e-2)" "unprognostic (3.79e-2)" "unprognostic (8.79e-2)" "unprognostic (1.95e-1)" "unprognostic (5.37e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (6.48e-4)" "unprognostic (1.57e-1)" "unprognostic (5.17e-3)" "unprognostic (3.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" 5.6 2.9 1.0 1.9 1.1 1.0 12.2 1.2 1.4 14.9 33.0 13.8 1.0 4.8 10.3 16.4 50.5 1.9 4.5 2.0 1.6 9.6 1.2 17.5 0.6 5.4 6.7 1.2 6.3 7.5 2.1 6.0 4.1 11.1 6.0 52.8 11.3 10.2 18.3 51.6 4.8 2.3 4.2 3.7 7.1 33.9 2.6 1.5 25.2 18.5 4.8 9.5 14.5 2.7 2.6 0.0 0.0 0.0 0.5 0.0 25.4 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.5 1.7 0.1 33.8 0.3 28.5 0.0 0.0 0.0 0.0 1.2 0.0 1.2 0.0 0.0 0.0 73.1 0.1 9.0 3.8 0.1 0.0 0.0 0.0 0.4 36.4 0.0 0.0 0.0 0.9 1.0 0.0 0.0 0.0 0.0 9.8 0.5 0.0 4.1 0.1 112.5 1.3 23.4 0.7 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 2.9 5.2 0.0 1.8 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 47.0 0.2 0.4 0.0 0.0 0.4 1.0 1.1 1.2 1.4 2.0 1.6 5.4 6.7 4.1 4.2 2.6 2.7 0.2 0.0 1.5 2.6 0.8 32.9 44.0 104.2 23.9 7.9 0.4 1.5 5.1 7.2 21.0 0.0 27.1 12.5 0.0 2.4 0.0 0.3 501.1 4.5 1.1 3.9 0.0 0.0 0.5 0.0 21.1 2.0 4.6 0.6 1.3 0.0 7.9 1.5 3.0 0.0 1.3 4.8 8.2 5.0 6.9 1763.3 7.5 3.8 65.8 1.0 2.7 84.9 0.0 0.0 0.2 0.1 0.5 7.2 0.2 15.2 0.7 0.5 39.3 79.7 19.7 7.3 3.4 7.6 4.6 28.8 30.3 10.5 2.2 0.0 1.6 37.6 ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Group enriched" "Detected in many" 4 "Microglial cells: 912.5;Oligodendrocytes: 698.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 35.8;HUVEC TERT2: 45.9;SK-MEL-30: 62.3;TIME: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" 8.8 1.4 5.8 1.8 13.3 3.1 6.4 14.3 8.4 1.9 10.4 2.0 0.7 5.9 0.5 1.9 2.7 2.5 4.4 6.9 9.0 8.7 2.0 5.2 2.0 15.2 10.6 2.3 0.9 4.4 2.1 3.1 17.2 1.1 2.4 3.9 1.1 1.6 1.6 0.8 1.4 4.5 13.3 1.4 1.5 0.3 11.3 0.9 13.3 6.5 0.7 2.6 1.6 21.0 0.2 0.0 35.8 0.0 0.6 0.0 0.0 0.0 4.2 0.6 0.4 11.9 0.1 0.6 2.4 0.3 2.3 0.1 0.0 0.4 0.3 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.6 0.0 0.0 1.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 2.9 0.0 1.8 1.7 0.0 0.0 0.0 2.7 8.8 0.0 0.0 62.3 8.3 0.0 0.2 20.6 0.3 2.8 0.1 3.3 0.0 0.0 0.0 0.0 8.4 5.5 0.0 6.3 2.8 0.0 2.2 0.0 2.6 0.3 0.5 2.3 3.8 1.3 1.4 3.9 0.3 4.3 0.0 0.0 1.9 5.8 13.3 14.3 8.4 6.9 9.0 15.2 10.6 17.2 13.3 11.3 21.0 59.8 3.2 1.5 174.3 5.6 0.3 0.2 0.0 0.6 3.2 0.6 1.0 1.2 0.0 0.0 3.7 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.1 4.5 23.2 0.0 0.4 107.0 0.0 0.1 2.5 3.6 0.1 0.0 0.8 66.0 0.8 1.1 0.0 101.4 0.5 0.0 9.8 0.7 0.8 0.0 3.7 5.4 912.5 3.0 12.3 1.0 23.1 698.3 0.2 3.4 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.3 0.2 0.7 0.1 0.4 0.1 2.0 6.9 0.3 0.1 ST8SIA1 "SIAT8, SIAT8A" ENSG00000111728 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1" Q92185 12 22063773-22437041 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.2;Inhibitory neurons: 152.0;Oligodendrocyte precursor cells: 198.0" "Cancer enhanced" "Detected in some" "glioma: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.5;ASC TERT1: 4.2;hTERT-RPE1: 3.0;RPTEC TERT1: 3.3;SK-MEL-30: 6.2;WM-115: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026775 Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA026775: AB_1857534" "unprognostic (1.98e-1)" "unprognostic (5.76e-3)" "unprognostic (1.79e-1)" "unprognostic (9.58e-2)" "unprognostic (2.89e-1)" "unprognostic (6.44e-3)" "unprognostic (1.76e-2)" "unprognostic (1.07e-2)" "unprognostic (3.07e-1)" "unprognostic (1.99e-1)" "unprognostic (6.37e-3)" "unprognostic (2.80e-2)" "unprognostic (1.07e-8)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "unprognostic (5.28e-2)" "unprognostic (3.16e-2)" 1.0 3.5 7.3 2.5 7.0 1.2 2.9 15.0 6.6 2.6 0.0 3.7 0.1 2.3 0.6 1.3 1.3 1.0 2.3 6.3 9.8 0.7 0.2 2.0 4.6 11.6 9.2 1.2 0.5 6.4 0.2 0.1 9.3 3.1 1.6 6.0 1.4 2.0 0.4 2.1 1.3 2.2 8.6 1.3 1.1 0.4 6.8 0.9 0.7 0.4 4.8 4.1 1.8 6.4 0.0 0.3 6.5 0.0 1.0 4.2 0.6 0.0 0.0 0.1 0.3 0.2 0.1 0.8 0.0 0.0 0.1 0.3 0.0 0.1 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.1 0.6 3.0 0.1 0.0 0.0 0.4 0.2 0.0 0.9 0.2 1.6 2.6 0.0 0.0 0.1 0.1 3.3 0.0 0.0 0.1 0.0 0.1 6.2 0.2 0.5 0.0 0.0 0.5 0.6 0.0 1.0 0.5 0.4 0.5 1.0 0.0 6.5 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.7 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.8 0.1 7.3 7.0 15.0 6.6 6.3 9.8 11.6 9.2 9.3 8.6 6.8 6.4 0.6 0.0 1.8 43.1 0.4 4.5 0.4 1.4 0.0 9.6 7.2 5.8 4.1 0.0 1.6 0.0 45.9 3.6 1.7 0.1 1.9 0.0 12.8 8.7 2.9 1.3 0.0 3.2 133.2 0.0 13.8 8.3 0.0 0.3 34.1 2.6 1.8 0.0 0.9 5.0 152.0 0.0 0.0 0.0 2.7 5.0 0.3 0.5 12.4 17.8 0.2 46.2 0.0 198.0 4.7 0.0 0.0 0.0 0.7 3.5 0.0 0.5 9.4 4.2 0.0 43.9 2.3 6.3 6.3 0.0 2.4 3.7 5.9 31.3 0.0 0.2 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387855 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.2;brain: 24.4" "Cell type enriched" "Detected in many" 19 "Oligodendrocyte precursor cells: 306.6" "Group enriched" "Detected in many" 5 "glioma: 4.3;melanoma: 11.9;thyroid cancer: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 13.6;SK-MEL-30: 48.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040236 Approved Centrosome NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 1.3 11.2 5.9 0.6 9.5 0.0 1.2 13.2 3.1 1.0 1.0 2.3 0.5 0.5 2.6 0.3 0.8 1.5 1.0 3.5 14.4 3.4 0.1 1.2 0.0 11.7 24.4 2.5 2.6 0.1 8.1 0.1 17.0 1.0 0.3 2.6 0.9 0.8 0.2 3.7 0.7 0.4 10.4 0.3 1.2 1.0 14.0 0.1 8.7 0.5 0.0 1.7 1.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.2 4.4 13.6 1.2 0.5 0.0 0.0 48.6 0.2 0.0 0.0 0.1 0.0 0.5 0.7 0.4 1.0 0.2 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 9.5 13.2 3.1 3.5 14.4 11.7 24.4 17.0 10.4 14.0 10.1 0.2 0.0 2.6 8.5 0.0 1.5 0.2 1.4 0.0 1.8 1.3 0.5 0.5 0.0 1.0 1.8 0.0 0.0 0.0 0.1 1.9 1.8 6.9 0.2 0.5 0.1 0.0 0.0 4.6 2.7 0.0 2.7 0.0 0.7 0.0 4.2 0.0 0.0 0.1 0.0 5.2 0.0 2.0 0.0 1.0 10.5 0.9 0.2 16.0 0.0 0.0 4.0 0.0 306.6 0.7 5.5 0.0 4.1 0.0 0.3 0.0 4.1 0.2 1.0 0.0 5.4 0.5 0.0 0.1 0.0 0.3 0.1 0.1 1.4 0.0 0.6 STX7 ENSG00000079950 "Syntaxin 7" O15400 6 132445867-132513198 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 53.6;classical monocyte: 51.6;eosinophil: 49.1;intermediate monocyte: 58.1;memory B-cell: 85.9;myeloid DC: 61.6;naive B-cell: 106.8;neutrophil: 83.2;non-classical monocyte: 61.6;plasmacytoid DC: 73.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001467, CAB062564" Enhanced Supported Lysosomes NA NA 380000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 57: B-cells - Immune response" Lysosomes "CAB062564: AB_2665605, HPA001467: AB_1857623" "unprognostic (1.91e-3)" "unprognostic (1.06e-3)" "unprognostic (2.67e-2)" "unprognostic (7.95e-3)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (4.52e-2)" "unprognostic (4.46e-1)" "unprognostic (4.19e-2)" "unprognostic (2.84e-1)" "unprognostic (2.79e-1)" "unprognostic (1.65e-3)" "unprognostic (2.16e-1)" "unprognostic (2.06e-1)" "unprognostic (1.67e-1)" "unprognostic (8.42e-2)" 35.1 17.7 17.6 41.5 20.4 21.6 21.2 20.8 21.1 22.5 11.5 25.1 37.2 27.2 12.1 33.7 22.1 33.5 36.0 19.8 21.0 51.1 18.3 31.5 76.3 23.2 22.2 30.9 14.3 20.5 7.4 42.9 22.4 19.5 29.1 15.9 20.6 25.9 23.1 20.4 37.9 29.2 21.2 45.5 28.3 8.2 18.0 17.7 30.8 22.7 71.8 26.2 16.6 29.3 17.5 17.5 28.7 20.6 56.4 49.9 22.6 33.9 34.7 34.4 49.3 30.9 28.9 87.6 32.7 41.1 51.0 22.8 25.5 31.2 46.6 30.2 30.4 33.1 14.6 33.0 44.6 22.8 24.2 28.6 28.5 35.3 31.6 46.5 37.8 19.2 36.1 30.7 39.8 24.8 10.4 18.2 11.0 25.4 20.2 24.6 22.5 25.5 57.9 20.4 23.5 7.1 15.3 24.9 91.9 42.2 17.0 21.2 66.4 20.1 20.5 44.1 36.6 29.1 18.2 37.2 28.3 17.9 23.2 53.6 51.6 49.1 10.8 58.1 4.4 85.9 8.0 7.7 61.6 106.8 5.7 6.8 83.2 9.5 61.6 73.9 12.8 31.3 17.6 20.4 20.8 21.1 19.8 21.0 23.2 22.2 22.4 21.2 18.0 29.3 37.7 70.5 36.5 34.0 151.6 42.1 23.5 33.8 26.7 26.8 26.7 22.2 51.0 85.8 33.1 42.3 2.1 85.7 111.5 50.8 64.6 56.9 1.2 27.9 33.4 38.3 13.2 57.9 61.3 30.9 54.5 34.1 42.3 28.0 40.6 25.9 43.5 19.4 177.6 37.0 60.6 39.8 38.7 99.4 78.7 2.1 30.7 109.6 133.4 109.6 110.7 25.7 54.6 44.2 77.9 57.6 63.1 46.3 37.3 24.7 113.5 155.0 43.9 16.5 39.5 30.2 38.6 2.7 17.6 36.2 41.2 55.4 24.4 17.9 28.4 24.9 STXBP1 "hUNC18, MUNC18-1, rbSec1, UNC18" ENSG00000136854 "Syntaxin binding protein 1" P61764 9 127579370-127696027 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 174.5;pituitary gland: 66.4;retina: 214.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 131.0;Cone photoreceptor cells: 156.4;Excitatory neurons: 243.2;Inhibitory neurons: 157.5;Rod photoreceptor cells: 155.6" "Cancer enhanced" "Detected in all" "melanoma: 39.6" "Region enhanced" "Detected in many" "cerebral cortex: 174.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 144.1;SK-MEL-30: 131.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008209, HPA023483, CAB034434" Enhanced Approved Nucleoplasm,Cytosol NA NA 29000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "CAB034434: AB_2196699, HPA008209: AB_1857624, HPA023483: AB_1857625" "unprognostic (2.32e-2)" "unprognostic (7.33e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.47e-4)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.87e-2)" "unprognostic (2.31e-1)" "unprognostic (3.08e-3)" "prognostic favorable (9.81e-4)" "unprognostic (1.30e-2)" "unprognostic (1.67e-1)" "unprognostic (2.68e-2)" "unprognostic (5.51e-2)" "unprognostic (7.66e-2)" "unprognostic (3.36e-3)" 27.5 28.8 22.8 7.8 33.2 1.1 21.0 38.6 174.5 21.8 0.0 15.9 5.5 24.1 7.1 10.4 32.3 11.4 24.0 48.3 12.2 14.1 3.1 32.1 6.0 48.7 0.0 25.2 24.8 15.0 66.4 14.1 33.1 10.5 8.4 214.2 15.6 10.4 9.0 11.4 9.3 21.0 0.0 10.4 13.3 9.1 6.8 5.8 20.1 9.2 7.0 15.4 16.4 27.2 13.2 27.1 25.5 28.8 56.6 48.3 23.2 45.0 22.9 26.6 23.3 1.5 15.4 13.1 24.2 29.7 74.2 4.7 22.6 28.1 32.7 29.8 15.4 17.1 69.7 4.9 28.5 1.8 14.6 36.6 15.4 70.0 33.7 42.6 32.2 43.4 17.8 19.6 45.5 24.5 12.5 5.2 21.5 21.4 35.9 7.5 12.1 31.3 22.0 0.6 144.1 69.9 72.9 37.2 131.9 22.5 5.8 5.6 47.5 30.0 15.1 59.9 17.4 40.2 73.2 17.4 59.2 18.9 28.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.6 0.9 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.1 0.0 0.2 22.8 33.2 38.6 174.5 48.3 12.2 48.7 0.0 33.1 0.0 6.8 27.2 24.3 25.6 70.7 34.0 1.2 11.6 10.1 8.4 12.5 131.0 10.5 8.0 15.2 1.5 9.2 3.7 156.4 2.7 1.1 0.5 7.9 13.1 2.2 8.3 14.7 28.9 45.6 4.0 243.2 8.4 5.9 18.7 3.1 7.0 5.1 5.0 26.7 1.4 4.4 84.1 157.5 10.2 8.2 2.5 5.6 2.2 20.5 3.0 10.6 45.0 0.6 27.0 0.0 61.3 39.0 5.3 0.0 44.4 1.6 10.8 0.1 8.9 15.9 155.6 13.1 9.5 11.2 40.6 16.9 2.9 7.5 24.5 2.3 17.7 0.9 7.1 SUPT7L "KIAA0764, SPT7L, STAF65, STAF65gamma" ENSG00000119760 "SPT7 like, STAGA complex subunit gamma" O94864 2 27650809-27663840 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039565, HPA063643" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA039565: AB_10795109, HPA063643: AB_2685070" "unprognostic (1.10e-1)" "unprognostic (1.15e-1)" "unprognostic (3.07e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (7.54e-2)" "unprognostic (3.70e-1)" "prognostic unfavorable (4.46e-7)" "unprognostic (5.15e-2)" "unprognostic (1.43e-3)" "unprognostic (2.27e-2)" "unprognostic (1.97e-3)" "unprognostic (9.75e-3)" "prognostic unfavorable (1.53e-4)" "unprognostic (2.26e-1)" "unprognostic (4.86e-1)" "unprognostic (3.79e-1)" "unprognostic (5.23e-3)" 31.2 35.1 31.9 22.5 32.0 35.7 27.7 32.0 37.5 34.3 38.9 30.9 22.9 31.9 25.0 25.8 32.2 20.4 36.8 31.9 33.3 33.4 37.8 29.6 27.4 31.1 31.9 39.6 31.1 22.8 46.2 27.1 32.0 34.0 25.3 55.5 24.0 22.1 30.2 20.8 32.7 28.1 30.3 41.6 29.8 20.6 31.9 26.2 36.3 27.1 24.2 29.2 29.5 35.4 33.6 28.6 41.2 31.9 36.8 30.1 49.0 32.0 30.9 28.4 30.4 37.2 36.8 29.2 32.9 34.0 40.0 35.8 37.3 35.6 27.6 33.7 36.1 39.8 43.7 42.4 48.1 32.4 37.5 42.3 43.8 42.0 44.0 52.7 37.3 35.3 45.8 34.0 37.3 23.1 28.1 52.9 27.5 33.5 25.0 26.8 44.1 37.4 36.7 31.1 32.5 42.3 28.6 29.6 54.7 52.0 20.5 27.9 28.8 39.2 29.0 19.9 30.8 60.9 47.8 60.4 30.5 39.8 27.3 30.4 14.8 13.6 18.2 15.7 20.7 10.6 14.3 19.0 20.9 17.3 17.2 16.3 3.7 22.9 14.7 14.0 17.6 13.6 31.9 32.0 32.0 37.5 31.9 33.3 31.1 31.9 32.0 30.3 31.9 35.4 15.3 22.4 17.1 33.6 15.9 8.4 13.2 19.9 13.1 18.6 12.7 11.7 21.3 12.8 21.6 22.0 41.7 34.2 25.8 12.1 21.5 18.1 12.5 19.1 18.3 18.5 10.8 11.1 31.2 14.6 29.3 17.7 21.4 14.7 19.6 20.7 15.7 15.6 25.1 15.2 32.7 12.3 12.2 12.3 11.1 3.9 13.7 17.1 3.6 14.0 13.4 19.0 16.5 17.6 33.1 13.9 8.2 15.4 25.5 8.5 10.8 20.6 24.3 24.7 19.7 15.0 16.5 29.4 22.6 15.4 8.7 42.3 19.3 22.1 13.9 11.6 SWT1 "C1orf26, FLJ20121, HsSwt1" ENSG00000116668 "SWT1 RNA endoribonuclease homolog" Q5T5J6 1 185157080-185291781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 38.3" "Cell type enhanced" "Detected in many" "Early spermatids: 150.8;Late spermatids: 52.7;Oligodendrocytes: 55.2;Spermatocytes: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 18.4;U-266/84: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024214, HPA027334" Enhanced Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA024214: AB_1845642, HPA027334: AB_1845643" "unprognostic (2.67e-3)" "unprognostic (1.32e-1)" "unprognostic (3.65e-1)" "unprognostic (4.26e-2)" "unprognostic (3.17e-3)" "unprognostic (8.41e-3)" "unprognostic (5.71e-3)" "unprognostic (9.26e-3)" "unprognostic (7.37e-2)" "unprognostic (2.68e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-1)" "prognostic favorable (5.63e-4)" "unprognostic (1.97e-1)" "unprognostic (4.19e-2)" "unprognostic (4.50e-2)" "unprognostic (4.35e-2)" 3.3 3.2 4.0 2.9 5.8 9.0 4.1 4.5 3.9 3.8 3.7 3.4 4.9 4.3 4.4 2.7 2.9 3.7 3.6 3.2 5.3 4.8 3.3 3.4 2.8 5.2 5.1 6.3 9.2 4.3 2.4 5.6 5.3 4.6 3.3 5.4 6.5 3.1 2.9 3.0 3.8 3.2 4.6 3.0 4.9 38.3 4.7 4.9 5.2 4.5 3.0 3.3 2.8 7.2 2.1 1.8 5.0 2.7 8.1 6.2 4.2 2.1 3.6 2.6 3.9 1.5 1.7 2.1 4.1 1.6 2.6 1.8 3.1 2.8 3.3 5.6 2.1 2.2 1.2 2.0 4.0 0.7 1.8 4.6 2.8 2.8 2.5 4.4 6.3 4.2 4.8 10.2 2.7 0.7 2.5 1.9 5.4 5.5 1.0 1.9 4.5 5.2 2.5 1.3 1.0 7.7 1.7 2.6 7.2 11.7 2.9 1.4 3.0 3.4 2.2 3.2 1.3 18.4 15.2 0.8 3.8 1.3 1.3 14.2 1.9 2.8 1.5 1.8 2.8 2.3 3.1 2.3 1.2 3.3 2.9 2.2 5.6 0.8 4.3 1.1 6.1 1.1 4.0 5.8 4.5 3.9 3.2 5.3 5.2 5.1 5.3 4.6 4.7 7.2 7.1 3.2 1.1 37.2 4.0 1.0 2.0 1.4 2.8 4.3 5.0 3.4 7.3 2.8 3.2 5.5 4.2 3.2 2.2 5.1 0.0 2.9 150.8 5.3 4.4 4.9 0.0 8.2 25.5 2.7 6.8 5.5 4.6 4.9 2.5 4.5 7.9 3.8 3.7 8.4 32.3 3.6 0.0 5.7 1.9 52.7 4.7 3.1 1.8 21.5 3.8 2.6 4.1 31.7 55.2 2.1 7.8 5.7 5.7 2.4 4.4 5.3 2.4 5.4 0.0 4.3 5.7 54.3 11.5 3.0 0.6 6.7 3.6 2.3 2.9 2.3 SYF2 "CBPIN, DKFZp564O2082, fSAP29, NTC31, p29" ENSG00000117614 "SYF2 pre-mRNA splicing factor" O95926 1 25222276-25232502 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018265, HPA070710" Approved Supported "Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "HPA018265: AB_10962002, HPA070710: AB_2686301" "unprognostic (4.19e-3)" "unprognostic (1.58e-2)" "unprognostic (9.98e-2)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (6.76e-2)" "unprognostic (6.76e-3)" "unprognostic (7.40e-3)" "unprognostic (2.36e-2)" "unprognostic (3.26e-1)" "unprognostic (1.33e-2)" "unprognostic (7.58e-2)" "unprognostic (4.89e-2)" "unprognostic (2.27e-2)" "unprognostic (4.80e-2)" "unprognostic (1.45e-3)" "prognostic favorable (5.72e-4)" 75.3 56.5 37.8 42.6 38.4 147.6 66.9 39.9 48.4 70.1 39.0 71.6 55.4 59.9 72.2 49.3 63.7 40.7 50.0 36.9 41.6 64.0 48.3 46.4 63.8 39.3 38.4 104.5 59.1 67.8 35.3 57.1 40.3 50.3 59.4 29.5 52.0 51.3 89.1 58.5 57.7 47.0 39.2 55.9 61.9 26.9 38.4 77.6 59.0 57.8 76.8 63.2 60.1 41.4 54.0 22.0 54.9 45.4 85.2 109.0 42.4 56.1 91.0 52.7 47.8 13.7 73.0 46.2 75.6 68.1 39.8 47.3 47.6 43.2 76.4 76.2 39.4 52.8 56.1 41.8 86.6 75.9 54.3 79.4 118.2 54.3 75.2 100.4 76.0 61.8 42.0 74.4 75.2 19.8 77.6 104.0 71.7 78.9 32.4 51.3 46.3 78.9 86.9 28.6 47.8 69.5 49.1 44.5 160.5 47.7 38.3 91.5 61.8 45.9 40.6 87.0 46.8 86.7 83.4 48.6 67.6 77.7 45.2 185.5 82.1 222.9 79.1 98.4 95.7 140.0 102.4 99.9 70.0 125.5 108.4 102.0 337.6 111.3 121.6 67.3 129.2 92.7 37.8 38.4 39.9 48.4 36.9 41.6 39.3 38.4 40.3 39.2 38.4 41.4 160.7 128.2 112.8 6.8 176.0 159.3 123.0 238.5 111.5 74.3 134.9 174.1 108.1 147.3 151.3 189.4 83.4 195.7 203.9 211.7 246.5 158.6 78.7 153.2 125.9 137.4 111.4 117.6 10.6 174.2 130.1 121.1 59.1 166.8 232.4 120.9 154.9 131.3 126.4 58.9 10.2 166.0 181.0 231.5 155.4 32.1 214.6 155.4 108.5 3.7 251.8 95.0 217.3 6.0 12.5 154.5 221.1 164.7 83.0 109.5 322.0 273.4 151.0 90.5 164.3 139.5 142.5 98.2 108.8 88.1 171.3 280.6 176.8 95.9 171.8 147.2 SYTL5 ENSG00000147041 "Synaptotagmin like 5" Q8TDW5 X 38006553-38128819 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.6;stomach 1: 12.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 37.2;Inhibitory neurons: 92.0;Intestinal goblet cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 6.2;MCF7: 5.8;OE19: 8.4;SK-MEL-30: 14.8;SuSa: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA026074 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Microtubules, Cytosol" "HPA026074: AB_1857697" "unprognostic (3.60e-2)" "unprognostic (1.71e-1)" "unprognostic (2.35e-1)" "unprognostic (6.68e-2)" "unprognostic (3.09e-3)" "unprognostic (3.22e-2)" "unprognostic (2.01e-2)" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.10e-1)" "unprognostic (6.72e-2)" "unprognostic (1.30e-2)" "unprognostic (5.21e-2)" "unprognostic (1.51e-1)" "unprognostic (1.47e-2)" "unprognostic (2.96e-2)" 0.0 8.2 6.5 0.3 7.2 0.0 2.5 0.0 5.6 5.6 0.1 2.8 2.2 2.2 0.8 3.1 0.4 0.5 1.1 6.7 10.7 1.2 4.4 0.6 0.0 3.4 13.6 0.1 5.8 0.0 0.6 7.4 6.3 0.9 3.2 0.5 2.2 0.4 0.0 0.1 2.4 3.3 2.5 0.0 12.1 0.6 8.6 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 1.2 0.2 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 6.2 1.4 0.0 0.0 0.5 2.2 0.7 0.0 0.0 0.0 0.0 0.6 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.7 0.1 0.0 0.1 0.2 0.2 5.8 0.0 0.0 2.5 8.4 0.0 0.0 2.0 0.0 0.0 0.4 3.2 0.0 0.3 1.2 14.8 19.5 0.0 0.0 0.0 0.1 4.7 0.0 3.3 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.5 7.2 0.0 5.6 6.7 10.7 3.4 13.6 6.3 2.5 8.6 0.9 0.0 0.0 2.0 1.6 0.0 0.0 0.2 0.8 0.0 0.0 4.0 1.5 0.3 0.0 8.7 0.0 0.0 3.3 0.0 4.6 0.0 0.0 0.0 0.7 3.6 0.1 3.0 0.0 1.4 0.9 3.6 0.6 37.2 4.0 0.0 1.0 0.4 1.3 0.3 0.0 92.0 20.8 6.1 0.0 0.0 0.0 0.6 0.2 0.0 1.0 0.2 0.0 0.0 0.0 1.1 4.9 3.0 2.6 0.3 0.6 0.6 0.1 3.3 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 8.9 0.1 0.0 0.7 1.0 TACR2 "NK2R, NKNAR, SKR, TAC2R" ENSG00000075073 "Tachykinin receptor 2" P21452 10 69403903-69416918 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 184.0" "Cell type enhanced" "Detected in some" "Horizontal cells: 6.7;Kupffer cells: 2.4;Leydig cells: 2.8" "Cancer enriched" "Detected in many" 4 "stomach cancer: 6.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 4.2;U-87 MG: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA076573 Approved "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA076573: AB_2732313" "unprognostic (2.83e-1)" "unprognostic (1.58e-3)" "unprognostic (2.48e-2)" "unprognostic (1.67e-1)" "unprognostic (4.22e-1)" "unprognostic (2.30e-1)" "unprognostic (1.30e-2)" "unprognostic (1.96e-2)" "unprognostic (3.72e-1)" "unprognostic (6.14e-2)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (9.88e-4)" "unprognostic (5.59e-3)" "unprognostic (4.31e-3)" "unprognostic (1.25e-3)" "unprognostic (1.32e-1)" 0.9 0.3 1.3 2.5 1.2 0.4 0.8 1.5 1.7 10.3 0.2 184.0 5.0 25.2 0.2 14.7 20.4 0.5 3.2 1.7 0.1 0.3 0.5 0.7 0.3 0.0 0.2 1.8 0.3 0.0 0.2 0.2 0.1 6.2 9.1 4.1 0.5 1.1 2.8 1.1 31.4 33.1 0.0 0.3 37.9 0.7 0.0 0.1 0.4 0.2 0.1 32.3 8.5 0.4 0.9 0.6 0.2 0.3 1.4 0.1 0.1 0.2 0.1 0.2 0.3 0.3 0.1 0.1 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.2 0.2 0.8 0.3 0.8 0.1 0.0 1.4 0.2 0.3 0.0 0.0 0.4 0.0 0.0 0.2 1.2 0.0 0.3 0.0 0.2 0.2 0.8 0.9 0.0 0.0 0.0 0.0 0.5 0.3 0.2 0.6 1.2 4.2 0.1 0.5 0.1 0.3 1.4 0.2 0.6 0.5 0.5 0.6 0.1 2.3 0.1 0.8 0.2 0.4 0.0 0.1 1.3 0.1 0.3 0.2 0.1 0.6 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.1 1.3 1.2 1.5 1.7 1.7 0.1 0.0 0.2 0.1 0.0 0.0 0.4 0.5 0.0 0.5 0.3 0.1 0.6 0.2 0.2 0.0 0.2 1.1 1.4 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.3 0.6 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.6 0.0 0.2 1.4 0.1 1.2 6.7 0.1 0.3 0.0 2.4 0.4 0.1 2.8 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.4 0.1 1.5 0.2 0.0 1.1 0.7 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.5 0.4 TAF12 "TAF2J, TAFII20" ENSG00000120656 "TATA-box binding protein associated factor 12" Q16514 1 28589323-28643085 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 244.4;Spermatogonia: 196.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008519 Approved NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA008519: AB_1080181" "unprognostic (4.81e-3)" "unprognostic (3.00e-1)" "unprognostic (3.51e-2)" "unprognostic (5.24e-3)" "unprognostic (4.14e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.88e-1)" "unprognostic (2.15e-2)" "unprognostic (4.32e-2)" "unprognostic (2.80e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (1.36e-7)" "unprognostic (4.02e-2)" "unprognostic (1.76e-1)" "unprognostic (2.12e-1)" "unprognostic (2.76e-2)" 18.3 15.4 15.3 16.7 16.3 18.2 16.4 17.2 20.6 19.3 18.6 16.4 13.1 14.6 17.8 19.2 14.9 13.8 20.6 15.2 16.2 17.9 19.2 14.6 24.3 16.1 16.1 16.5 17.7 16.3 14.8 15.7 16.3 12.3 15.0 16.2 14.0 10.3 22.4 19.9 13.2 15.4 15.9 16.2 14.2 22.4 16.2 29.3 13.6 16.8 25.9 17.1 17.4 17.7 39.0 19.3 27.2 18.0 63.7 71.5 16.6 47.0 29.8 29.7 38.6 10.5 33.7 50.3 43.9 43.9 23.0 31.0 45.7 39.8 48.4 29.0 16.7 49.9 20.5 17.6 42.0 39.1 21.1 41.2 42.5 53.2 50.1 31.4 31.3 42.8 43.3 37.3 48.6 38.2 46.0 32.4 37.8 45.2 33.0 46.5 26.8 32.2 42.5 15.7 10.4 25.9 61.6 32.3 70.1 31.8 25.7 46.2 27.9 12.1 21.4 48.8 48.1 43.9 42.6 40.0 28.4 64.8 34.5 105.1 44.7 115.6 38.5 45.6 40.2 40.1 37.7 43.4 39.1 36.1 32.3 40.4 106.4 50.6 49.2 31.0 55.3 41.2 15.3 16.3 17.2 20.6 15.2 16.2 16.1 16.1 16.3 15.9 16.2 17.7 34.4 32.1 16.5 7.8 35.4 29.4 30.8 74.2 32.5 14.8 34.5 43.2 26.6 22.8 32.2 23.9 6.2 69.3 34.9 21.1 58.7 33.6 41.0 22.5 36.5 29.3 7.7 24.2 9.9 39.6 82.3 38.3 14.3 20.1 25.4 13.0 28.2 33.4 79.0 3.3 10.8 21.4 52.9 51.0 33.6 13.1 50.1 43.7 30.2 7.5 68.2 28.0 51.5 9.5 11.5 40.8 29.6 33.4 35.9 34.7 37.6 68.8 19.6 27.3 32.9 31.5 41.5 244.4 196.4 34.2 33.2 117.1 43.3 28.3 23.9 28.6 TBC1D16 "FLJ20748, MGC25062" ENSG00000167291 "TBC1 domain family member 16" Q8TBP0 17 79932343-80035872 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Horizontal cells: 307.9" "Cancer enhanced" "Detected in all" "melanoma: 35.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.3" "Lineage enhanced" "Detected in single" "monocytes: 2.3" "Cell line enhanced" "Detected in many" "ASC diff: 179.1;SK-MEL-30: 192.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024482, HPA065839" Approved Approved "Intermediate filaments" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Intermediate filaments" "HPA024482: AB_1857790, HPA065839: AB_2685566" "unprognostic (4.53e-3)" "unprognostic (1.36e-2)" "unprognostic (1.80e-2)" "unprognostic (2.06e-2)" "unprognostic (4.92e-2)" "unprognostic (7.21e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (5.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (9.76e-2)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-3)" "unprognostic (3.99e-3)" 37.3 8.1 17.6 8.7 24.8 0.9 18.4 24.4 14.6 10.4 5.3 8.0 7.9 12.4 11.5 10.1 12.9 9.5 10.7 10.6 15.2 27.7 7.4 9.0 7.8 18.0 22.7 11.7 15.7 12.9 7.0 7.5 16.0 17.7 5.9 7.6 29.4 10.8 5.1 17.3 9.0 10.5 13.0 7.3 8.4 4.1 38.9 4.0 10.1 6.7 3.5 8.6 6.2 17.4 30.3 28.2 43.1 50.8 179.1 93.7 8.2 17.3 17.1 10.7 12.0 53.6 10.3 0.1 11.9 29.2 20.3 9.4 45.8 16.2 8.2 1.5 21.5 0.0 13.3 25.1 30.5 0.6 4.1 106.1 28.1 23.2 16.7 17.1 45.9 19.8 7.2 19.6 20.2 18.4 8.1 2.7 51.8 39.3 15.4 25.4 27.2 17.5 12.6 36.5 43.8 56.8 15.4 42.5 192.4 26.7 27.9 13.6 31.3 37.1 26.1 29.5 15.3 59.9 11.4 3.3 15.9 11.2 47.8 0.0 0.1 0.0 0.0 1.9 0.2 0.0 0.0 0.1 0.1 0.5 0.1 0.1 0.0 0.0 2.3 0.0 0.0 0.2 17.6 24.8 24.4 14.6 10.6 15.2 18.0 22.7 16.0 13.0 38.9 17.4 5.7 0.0 7.9 15.7 1.7 5.5 5.2 4.3 2.8 8.5 12.3 7.5 8.1 17.2 5.5 7.3 10.4 6.1 0.3 3.1 9.8 15.1 0.9 15.3 22.7 10.4 31.8 3.6 7.3 22.1 1.5 17.5 9.7 26.0 7.6 23.8 14.6 17.9 3.2 307.9 8.9 6.3 14.2 58.4 3.1 2.2 5.9 6.4 76.5 37.5 0.9 23.1 2.1 14.6 4.9 17.4 4.8 7.9 0.4 12.5 3.5 13.5 8.2 7.0 6.6 19.3 10.3 0.3 4.3 5.8 4.5 1.9 2.7 7.6 7.0 5.9 TBC1D20 "C20orf140, dJ852M4.2" ENSG00000125875 "TBC1 domain family member 20" Q96BZ9 20 423596-462566 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 147.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043613 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" "HPA043613: AB_10963930" "unprognostic (2.16e-3)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.14e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (3.68e-3)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (2.54e-2)" "unprognostic (1.35e-2)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "unprognostic (2.97e-1)" "unprognostic (2.20e-1)" "unprognostic (2.21e-1)" "unprognostic (9.52e-2)" 16.8 21.5 21.7 7.6 24.2 7.0 16.0 22.6 22.4 18.4 17.0 19.1 8.6 17.4 15.6 18.9 16.1 11.8 16.6 20.4 21.6 14.4 13.4 18.1 10.6 23.1 23.6 17.3 14.7 21.2 17.8 17.5 22.2 17.7 11.8 7.7 16.9 18.8 20.4 20.0 14.5 20.4 22.3 16.1 15.4 9.9 23.0 14.6 15.0 23.6 12.9 19.6 16.8 23.4 18.5 12.6 18.2 15.9 75.9 39.3 16.3 19.8 39.1 27.7 29.4 11.8 9.6 8.4 4.6 43.7 35.2 18.1 18.8 20.2 26.8 4.9 4.9 13.4 4.0 27.3 45.7 13.1 7.1 35.2 38.3 15.4 14.4 29.9 17.7 14.4 14.8 17.7 30.7 4.5 12.1 15.5 10.6 23.7 11.0 12.0 17.2 10.4 18.7 12.0 15.8 12.8 22.2 39.9 53.5 20.0 14.1 27.9 19.9 25.0 8.9 22.2 14.3 9.7 19.0 7.7 13.4 14.0 15.9 3.0 0.6 0.7 1.8 0.5 1.2 0.8 1.2 2.1 0.6 0.7 1.1 1.8 1.5 0.9 0.4 0.6 0.8 0.7 21.7 24.2 22.6 22.4 20.4 21.6 23.1 23.6 22.2 22.3 23.0 23.4 23.0 12.8 13.6 16.3 22.6 18.5 13.6 11.3 23.3 29.3 22.4 14.4 16.8 24.3 11.1 14.7 12.5 16.5 28.9 29.6 11.7 23.8 48.9 21.3 26.9 20.7 16.1 48.6 16.2 30.3 25.1 23.0 17.9 16.2 11.4 14.4 25.4 19.7 19.7 26.9 19.2 17.9 8.2 17.6 16.4 147.2 29.5 18.6 14.2 14.0 13.2 21.4 43.3 11.6 15.2 22.5 20.7 35.3 30.0 21.2 19.4 17.0 17.1 19.4 19.7 22.1 18.3 33.1 34.7 15.3 18.9 50.9 24.0 19.6 15.7 27.9 TBC1D7 "dJ257A7.3, FLJ32666" ENSG00000145979 "TBC1 domain family member 7" Q9P0N9 6 13266542-13328583 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "melanoma: 13.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 320.4;U-266/84: 174.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034748 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "HPA034748: AB_10671232" "unprognostic (9.53e-2)" "unprognostic (8.39e-2)" "unprognostic (3.18e-1)" "unprognostic (1.81e-2)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (3.95e-3)" "unprognostic (5.54e-2)" "unprognostic (9.30e-2)" "prognostic favorable (4.98e-5)" "unprognostic (4.36e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (2.03e-7)" "unprognostic (1.57e-1)" "unprognostic (3.46e-2)" "unprognostic (3.48e-1)" "unprognostic (2.78e-2)" 9.4 12.0 14.3 9.7 15.9 26.5 11.5 13.0 26.3 10.8 9.9 15.2 14.5 8.4 20.0 17.1 6.6 10.3 31.7 14.3 12.9 21.4 17.5 11.0 13.9 11.8 11.6 7.7 10.2 12.4 10.7 14.4 13.4 12.4 16.5 11.5 12.2 7.0 16.2 13.8 10.8 10.1 10.7 12.3 9.8 14.0 12.7 16.9 8.0 14.5 15.6 10.0 11.4 15.8 26.2 25.5 36.0 36.8 27.5 15.7 24.9 11.5 13.3 24.0 26.8 51.8 23.0 18.1 75.0 19.3 55.8 20.8 24.5 29.0 21.9 28.4 29.1 50.3 16.5 45.8 63.6 32.7 73.6 21.4 40.6 29.7 19.3 24.0 40.5 57.2 57.3 23.7 30.8 42.8 42.2 78.5 24.4 32.4 24.6 61.7 15.7 77.7 54.1 35.1 69.4 30.8 28.4 55.4 320.4 71.3 53.6 19.1 29.4 24.6 30.8 13.6 16.2 55.8 174.2 86.2 23.1 34.1 51.1 28.2 21.6 27.0 11.6 20.0 7.6 15.4 9.9 10.5 43.3 14.5 9.1 11.1 42.2 21.4 13.7 42.2 14.6 10.4 14.3 15.9 13.0 26.3 14.3 12.9 11.8 11.6 13.4 10.7 12.7 15.8 11.0 12.8 13.9 3.9 16.2 7.5 9.9 37.2 11.4 6.5 15.7 20.6 30.6 15.7 28.8 16.5 4.2 41.0 15.0 12.9 33.2 16.4 8.1 15.2 12.7 12.4 9.0 57.4 8.4 14.3 23.3 9.9 15.8 15.7 9.5 14.4 12.1 15.2 24.2 10.1 9.5 18.3 50.8 12.9 23.0 5.8 4.4 31.3 10.6 4.7 13.9 8.9 13.4 6.6 7.3 22.2 18.3 5.3 21.9 11.6 13.1 56.1 16.4 8.0 13.1 5.6 20.2 14.7 34.3 21.7 8.9 46.9 11.3 14.4 16.4 13.4 TDRD3 FLJ21007 ENSG00000083544 "Tudor domain containing 3" Q9H7E2 13 60396457-60573878 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 169.1;granulocytes: 152.3;Inhibitory neurons: 128.9;Oligodendrocyte precursor cells: 142.7;Oligodendrocytes: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034925, HPA067153" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Golgi apparatus, Cytosol" "CAB034925: AB_2240523, HPA067153: AB_2732759" "unprognostic (8.52e-2)" "unprognostic (3.19e-1)" "unprognostic (2.23e-1)" "prognostic favorable (2.77e-4)" "unprognostic (5.21e-2)" "unprognostic (2.62e-1)" "unprognostic (7.37e-2)" "unprognostic (5.79e-2)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (1.84e-1)" "unprognostic (6.18e-3)" "unprognostic (9.62e-2)" "unprognostic (9.95e-2)" "unprognostic (3.68e-2)" "unprognostic (4.40e-2)" "unprognostic (1.27e-3)" 8.8 8.2 14.2 6.8 18.7 5.8 12.0 18.2 16.4 10.6 12.7 9.9 9.5 10.8 9.9 10.4 9.8 9.2 10.7 11.8 16.0 11.4 9.4 12.5 9.1 17.1 15.5 14.0 14.1 10.9 7.7 6.0 16.6 8.0 11.1 10.9 9.3 7.4 16.7 11.3 8.7 9.2 16.0 8.7 11.2 12.3 17.9 11.9 12.0 18.5 9.2 8.1 7.7 21.2 6.7 7.3 15.3 36.7 5.9 13.3 9.5 7.6 8.4 8.7 5.6 4.9 10.9 16.0 3.0 11.1 7.4 8.9 12.6 11.0 9.4 12.5 10.1 30.4 13.7 9.4 12.0 21.3 15.4 8.9 15.4 5.1 15.1 17.9 12.0 13.3 6.7 9.7 9.5 7.4 19.5 11.4 11.7 24.4 5.5 10.1 7.5 11.0 12.0 8.8 13.8 16.4 10.9 13.2 27.9 10.9 6.8 9.3 10.2 5.4 5.6 6.1 8.5 18.8 17.7 13.7 5.0 11.0 16.7 0.3 1.4 1.6 3.2 2.2 2.3 2.2 3.7 3.7 2.1 1.4 3.0 3.8 0.1 2.1 1.7 4.6 4.5 1.3 14.2 18.7 18.2 16.4 11.8 16.0 17.1 15.5 16.6 16.0 17.9 21.2 24.5 22.4 30.0 169.1 13.8 7.9 9.6 9.3 14.8 30.9 10.8 10.2 44.4 11.5 18.2 11.0 54.2 8.8 18.7 11.5 21.5 13.4 20.9 18.8 24.4 15.9 17.4 7.2 101.1 17.8 10.6 18.5 18.3 15.7 152.3 26.1 11.7 8.8 6.9 20.2 128.9 12.8 12.2 9.5 7.8 24.4 19.0 22.2 19.6 69.3 12.2 12.7 20.6 142.7 168.7 10.6 19.2 18.4 14.6 7.1 12.4 12.3 22.8 30.6 6.6 32.9 12.9 38.9 21.6 14.1 6.7 6.7 20.9 30.6 14.0 8.0 TFPT "amida, FB1, INO80F" ENSG00000105619 "TCF3 fusion partner" P0C1Z6 19 54107020-54115657 "Disease related genes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 135.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034958, HPA058534" Approved Supported Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA034958: AB_10603036, HPA058534: AB_2683745" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (5.13e-4)" "unprognostic (6.56e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (5.25e-4)" "unprognostic (3.85e-1)" "unprognostic (2.85e-1)" "unprognostic (2.71e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.80e-2)" "unprognostic (1.15e-1)" "unprognostic (2.00e-2)" "unprognostic (2.61e-1)" "unprognostic (3.43e-1)" "unprognostic (3.66e-2)" 12.1 15.8 27.4 8.9 25.2 10.4 12.8 23.1 41.3 11.7 18.6 15.7 9.7 11.7 4.3 10.0 9.9 7.2 16.1 26.5 24.7 12.0 10.5 12.3 10.7 24.1 25.0 9.5 8.7 9.2 10.9 8.4 24.3 22.2 4.1 5.0 13.1 5.4 19.4 13.2 12.2 6.1 20.9 19.1 14.1 9.1 24.0 13.5 11.2 10.6 6.4 12.3 9.4 28.0 23.5 28.5 18.2 12.9 6.7 9.5 11.8 25.1 15.5 23.9 24.5 17.8 23.6 20.5 20.2 12.8 12.5 11.2 10.8 19.6 7.8 43.5 52.2 30.7 27.5 20.8 39.6 16.1 34.7 11.2 9.5 18.8 15.7 11.5 18.7 30.8 19.3 45.8 9.2 30.2 34.3 47.2 11.0 34.1 19.8 30.6 10.0 15.4 10.0 35.9 19.2 17.4 9.2 38.4 45.1 5.6 14.0 48.9 37.8 52.4 19.3 7.5 36.9 33.8 48.2 18.5 20.7 40.4 34.4 10.5 9.2 6.4 15.4 10.7 14.6 9.4 19.4 20.1 19.0 9.3 16.2 17.2 6.5 21.4 3.9 43.3 26.0 11.2 27.4 25.2 23.1 41.3 26.5 24.7 24.1 25.0 24.3 20.9 24.0 28.0 25.3 16.0 7.2 5.2 12.2 17.0 9.8 25.5 12.0 10.9 31.4 32.3 2.5 12.8 28.6 22.0 2.1 22.4 30.3 22.5 15.6 21.0 9.6 27.1 8.2 29.5 15.6 7.8 5.0 27.6 29.1 11.3 11.2 13.3 15.2 20.8 37.9 9.6 135.7 0.0 4.1 35.7 32.6 28.1 41.0 5.5 12.2 43.5 39.2 1.0 49.7 17.8 25.7 2.5 3.6 55.9 18.4 17.0 13.1 31.9 23.0 24.8 46.4 12.4 6.6 7.8 16.5 11.0 16.0 5.8 17.3 26.1 22.8 41.1 16.1 13.0 THAP1 "4833431A01Rik, DYT6, FLJ10477" ENSG00000131931 "THAP domain containing 1" Q9NVV9 8 42836674-42843325 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" DNA-binding "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071310 Supported Nucleoplasm No No "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA071310: AB_2686386" "unprognostic (8.99e-3)" "unprognostic (3.97e-3)" "unprognostic (7.15e-3)" "unprognostic (1.87e-2)" "unprognostic (2.55e-1)" "unprognostic (6.38e-2)" "unprognostic (1.20e-1)" "unprognostic (4.03e-1)" "unprognostic (3.91e-2)" "unprognostic (5.95e-2)" "unprognostic (9.43e-2)" "unprognostic (9.19e-2)" "unprognostic (2.94e-2)" "unprognostic (1.28e-1)" "unprognostic (2.82e-1)" "unprognostic (1.95e-1)" "unprognostic (3.16e-2)" 7.3 5.7 4.9 6.9 5.1 8.3 7.4 7.3 7.5 6.2 4.9 6.2 5.9 6.9 6.2 6.3 7.3 5.1 8.8 4.9 4.7 7.0 8.7 5.4 9.5 5.2 4.8 8.2 4.6 7.9 3.8 7.0 5.3 5.7 5.4 5.7 6.2 5.7 12.4 4.0 5.8 6.8 5.2 6.3 5.0 9.4 5.2 11.5 8.6 12.5 8.4 6.5 3.7 6.4 10.5 9.3 8.5 8.2 12.7 14.3 10.2 14.2 10.8 12.8 11.7 8.0 13.2 12.8 11.3 10.5 19.0 10.7 14.0 12.0 16.2 12.4 10.3 12.5 8.1 9.4 15.6 10.4 12.7 11.3 17.7 14.1 18.2 12.4 16.5 17.1 14.1 14.7 15.1 6.4 25.1 12.1 16.8 16.9 7.4 11.2 15.2 10.2 13.9 7.8 6.9 8.1 15.5 9.7 20.2 11.2 13.5 11.6 10.0 11.2 8.3 15.0 14.3 11.9 14.0 12.2 11.2 13.6 12.4 23.8 18.6 30.8 19.9 16.7 21.6 20.4 23.1 22.1 19.9 17.8 26.9 21.5 22.0 19.3 18.0 9.8 32.5 18.8 4.9 5.1 7.3 7.5 4.9 4.7 5.2 4.8 5.3 5.2 5.2 6.4 17.2 9.6 9.4 3.6 20.1 13.5 9.4 16.6 26.7 10.5 12.3 11.4 21.5 7.2 12.6 5.5 0.0 20.5 17.5 7.7 23.5 17.5 35.6 16.1 16.2 15.5 14.3 18.3 5.2 11.3 23.8 14.5 2.6 13.3 16.5 8.6 10.4 12.1 15.2 23.5 5.3 8.8 28.5 11.6 9.2 17.9 11.5 13.4 7.2 2.8 20.2 15.6 30.9 5.5 4.9 10.6 4.0 13.9 18.5 10.8 14.1 22.9 13.1 11.0 0.0 12.9 17.0 32.6 45.8 21.1 13.8 8.1 24.6 12.8 9.6 8.2 THAP3 ENSG00000041988 "THAP domain containing 3" Q8WTV1 1 6624866-6635586 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067114 Approved Approved Nucleoplasm,Nucleoli,Mitochondria No No "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli, Mitochondria" "HPA067114: AB_2685782" "unprognostic (1.82e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (2.89e-2)" "unprognostic (2.87e-1)" "unprognostic (1.61e-1)" "unprognostic (2.14e-3)" "unprognostic (1.13e-1)" "unprognostic (2.70e-1)" "unprognostic (4.63e-2)" "unprognostic (3.50e-3)" "unprognostic (4.30e-2)" "unprognostic (1.11e-2)" "unprognostic (4.51e-2)" "unprognostic (1.08e-1)" "unprognostic (2.67e-1)" "unprognostic (2.26e-3)" 17.4 24.7 22.1 6.5 22.3 9.6 17.9 23.1 25.8 23.4 18.9 20.1 7.9 18.8 8.3 15.7 19.4 7.7 28.4 20.9 21.3 27.0 29.0 14.1 11.5 23.7 21.8 22.3 24.0 14.0 19.7 7.4 22.2 22.9 4.5 5.1 16.5 9.9 22.8 17.0 15.1 7.0 21.0 21.6 19.2 16.8 21.9 9.7 19.9 13.4 8.6 18.9 18.2 25.0 13.6 12.8 11.2 16.3 18.2 16.3 10.8 12.0 15.6 31.2 19.4 17.1 8.4 11.9 15.7 13.2 11.6 10.5 17.9 10.7 10.8 20.6 30.1 13.7 18.5 15.5 22.8 9.8 13.6 15.3 13.4 19.7 17.2 19.0 13.6 20.5 14.1 14.9 11.7 9.7 17.2 22.2 9.7 15.8 21.7 16.2 13.6 17.3 14.3 3.2 14.7 16.7 14.6 19.9 28.6 9.3 12.8 17.4 12.4 16.5 9.9 11.4 19.0 16.7 19.3 15.9 13.9 20.9 9.5 16.6 19.4 15.2 25.2 16.2 25.7 22.1 25.0 26.8 24.4 31.0 27.3 23.1 12.0 24.7 12.9 22.2 27.1 20.9 22.1 22.3 23.1 25.8 20.9 21.3 23.7 21.8 22.2 21.0 21.9 25.0 12.1 0.0 7.5 5.5 10.8 14.0 12.0 13.2 9.1 11.1 10.4 14.2 7.2 10.0 6.9 9.2 6.2 16.0 9.7 10.7 19.6 10.5 6.5 9.2 11.8 12.8 7.7 11.0 4.6 10.4 17.5 15.8 5.6 9.0 5.7 17.6 11.7 11.6 15.5 5.0 5.8 10.4 10.2 10.9 15.9 4.7 18.6 7.1 10.6 2.8 19.2 12.2 12.3 5.0 7.9 9.8 13.1 23.3 18.1 21.5 21.1 19.3 12.3 8.8 13.1 13.8 15.8 18.2 18.0 8.7 14.8 16.4 9.3 17.7 13.0 15.6 THEM4 CTMP ENSG00000159445 "Thioesterase superfamily member 4" Q5T1C6 1 151870866-151909637 "Enzymes, Predicted intracellular proteins" "Apoptosis, Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 104.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 30.3" "Low region specificity" "Detected in all" HPA028161 Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "HPA028161: AB_10603454" "unprognostic (2.88e-2)" "unprognostic (1.93e-1)" "unprognostic (1.50e-1)" "unprognostic (1.04e-2)" "unprognostic (1.29e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.15e-3)" "unprognostic (2.23e-2)" "unprognostic (1.07e-1)" "prognostic favorable (2.51e-4)" "unprognostic (1.17e-1)" "unprognostic (4.19e-2)" "unprognostic (3.02e-2)" "unprognostic (9.25e-2)" "unprognostic (1.91e-1)" "unprognostic (5.93e-3)" 4.6 8.2 2.9 5.5 4.1 3.1 4.8 4.8 4.0 4.6 4.4 3.7 4.1 5.2 6.9 3.2 4.2 3.6 6.8 2.6 3.9 10.0 7.9 3.6 6.0 4.1 3.6 4.4 8.9 8.4 6.0 2.5 4.5 4.3 4.4 15.9 4.1 6.1 10.4 3.4 4.6 3.2 2.3 4.9 4.7 6.1 4.1 3.1 5.8 3.0 6.2 5.2 3.1 5.9 5.4 5.9 1.1 5.2 5.2 3.9 5.2 4.7 3.7 3.7 3.7 5.7 4.0 10.5 7.2 4.3 2.8 5.6 2.5 12.1 5.0 11.8 3.5 16.5 9.4 5.5 4.2 16.0 8.0 7.5 5.6 4.5 5.3 5.2 7.8 0.4 19.4 9.4 7.3 7.4 0.3 5.2 18.6 5.4 10.9 0.2 1.0 2.5 5.6 4.9 6.3 11.2 2.8 5.0 30.3 10.3 9.8 9.4 9.3 0.8 4.8 4.0 2.2 18.5 21.2 7.5 7.8 11.8 24.9 2.6 0.8 2.3 7.2 2.4 10.5 3.9 14.4 7.1 2.4 2.1 14.9 10.5 1.1 7.9 0.8 6.8 22.2 3.3 2.9 4.1 4.8 4.0 2.6 3.9 4.1 3.6 4.5 2.3 4.1 5.9 9.6 6.4 15.1 11.4 20.5 5.6 8.0 9.6 17.6 36.4 17.3 19.3 19.1 12.8 9.9 14.7 104.3 29.7 32.6 4.6 41.1 19.1 39.8 19.0 12.8 13.5 18.1 22.1 18.1 19.5 21.5 16.1 13.7 36.6 23.5 22.4 23.9 17.6 12.8 13.5 21.6 7.4 20.3 5.1 12.3 30.4 16.8 8.7 21.4 5.6 10.4 25.5 26.8 30.2 24.9 15.1 9.2 16.1 18.5 6.3 13.6 27.8 4.9 73.3 13.1 21.2 9.7 37.4 24.5 11.7 4.4 10.3 37.9 31.6 12.2 5.5 TM2D1 BBP ENSG00000162604 "TM2 domain containing 1" Q9BX74 1 61681046-61725423 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046058, HPA055621" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Vesicles "HPA046058: AB_2679519, HPA055621: AB_2682865" "unprognostic (1.80e-1)" "unprognostic (1.99e-3)" "unprognostic (1.68e-1)" "unprognostic (2.20e-2)" "unprognostic (5.79e-1)" "unprognostic (5.23e-2)" "prognostic unfavorable (2.02e-7)" "unprognostic (1.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.00e-1)" "unprognostic (2.28e-2)" "unprognostic (1.15e-2)" "unprognostic (4.60e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "unprognostic (1.09e-1)" 30.9 36.3 25.4 16.5 26.0 23.2 35.8 27.3 36.5 29.4 27.6 27.7 20.5 30.3 45.3 21.4 29.9 26.0 45.4 25.2 27.0 38.8 29.3 27.4 26.5 26.7 27.0 36.4 21.8 41.6 20.4 35.7 26.8 33.3 28.5 26.2 30.1 22.5 40.9 19.8 25.0 29.3 27.1 23.9 24.4 34.9 25.9 25.1 40.6 35.3 20.3 30.1 20.7 28.4 31.3 15.0 22.8 18.2 68.1 66.2 29.2 54.5 55.2 26.4 35.0 9.7 39.0 25.3 70.9 45.9 52.7 34.8 29.2 39.7 40.5 41.3 34.4 28.2 23.0 21.8 66.7 40.9 48.0 74.2 67.0 30.5 38.0 64.4 50.5 33.6 32.7 47.7 64.7 10.1 20.9 32.0 24.9 27.5 21.4 17.9 43.1 31.5 78.4 24.3 25.4 30.9 32.5 64.1 102.6 30.5 35.1 43.2 45.3 35.3 17.8 19.8 41.9 40.0 39.4 30.8 61.3 39.4 31.8 52.8 18.7 44.9 16.1 23.7 16.6 24.2 18.6 19.7 18.6 20.1 17.2 19.9 12.2 23.3 26.8 36.4 24.3 19.4 25.4 26.0 27.3 36.5 25.2 27.0 26.7 27.0 26.8 27.1 25.9 28.4 49.5 41.7 40.2 32.3 49.0 78.3 91.9 205.2 59.2 60.3 67.7 56.6 40.5 48.6 99.9 79.1 60.5 51.2 47.4 46.5 39.2 50.3 6.5 43.3 34.7 59.2 43.9 42.1 42.3 45.3 60.0 84.3 29.0 42.2 61.5 37.6 80.7 54.2 50.3 69.0 46.9 41.3 158.7 58.7 53.8 9.9 79.9 48.1 90.7 43.1 54.1 99.2 63.8 50.3 63.4 54.2 60.4 53.0 51.4 110.0 45.9 67.6 100.0 70.1 39.5 75.3 60.0 172.1 72.5 58.6 76.4 53.5 47.3 42.0 43.0 110.1 TMEM255A "FAM70A, FLJ20716" ENSG00000125355 "Transmembrane protein 255A" Q5JRV8 X 120258650-120311556 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.7;ovary: 19.6" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 32.6;Skeletal myocytes: 14.6" "Group enriched" "Detected in many" 10 "glioma: 21.3;melanoma: 8.0;renal cancer: 7.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.8" "Lineage enriched" "Detected in single" 9 "T-cells: 2.8" "Cell line enhanced" "Detected in some" "Karpas-707: 25.3;NTERA-2: 9.5;RPMI-8226: 17.1;SK-MEL-30: 27.7;U-2 OS: 11.8;U-87 MG: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048470 Approved Uncertain "Nucleoplasm,Nuclear bodies" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "HPA048470: AB_2680406" "unprognostic (3.41e-2)" "unprognostic (8.96e-2)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (3.38e-1)" "unprognostic (1.56e-1)" "unprognostic (8.55e-4)" "unprognostic (7.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.36e-1)" "unprognostic (1.49e-3)" "unprognostic (2.02e-1)" "unprognostic (1.32e-2)" "unprognostic (3.13e-2)" "unprognostic (1.45e-1)" "unprognostic (6.17e-2)" "unprognostic (2.55e-4)" 4.7 3.3 7.4 1.8 5.8 0.7 3.2 4.8 9.2 11.9 1.7 2.6 0.7 1.9 1.6 2.8 3.8 1.1 1.3 3.8 27.4 1.4 0.6 3.0 3.6 22.7 48.7 19.6 0.4 1.4 3.8 0.2 33.0 1.4 2.3 1.5 1.2 1.8 1.4 2.6 2.3 0.9 19.9 1.7 1.8 0.2 36.8 8.1 0.4 2.7 3.8 1.9 8.5 11.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.5 0.2 0.0 0.1 0.3 0.0 2.9 0.0 1.9 0.7 0.7 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 25.3 0.4 0.0 0.0 0.1 9.5 0.0 0.0 0.1 0.0 17.1 0.0 0.0 5.1 0.1 0.5 0.0 27.7 0.3 0.0 0.3 0.0 0.0 11.8 0.0 5.1 0.0 5.2 3.7 29.7 0.0 0.0 0.0 0.3 0.0 2.8 0.1 1.4 0.2 0.2 1.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.4 7.4 5.8 4.8 9.2 3.8 27.4 22.7 48.7 33.0 19.9 36.8 11.5 0.1 3.2 0.0 1.6 0.0 0.4 0.1 0.1 0.6 1.9 0.2 1.3 0.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.5 0.0 0.0 0.2 0.0 0.0 4.4 0.0 0.4 0.0 0.3 0.4 0.0 1.3 0.0 4.3 0.0 0.0 1.0 0.7 1.6 0.6 1.6 5.4 1.9 3.7 0.3 0.0 32.6 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.5 0.0 14.6 0.6 0.1 0.1 0.0 1.3 0.1 0.4 0.0 0.0 0.0 TMEM272 "FLJ37307, LINC00282, NCRNA00282" ENSG00000281106 "Transmembrane protein 272" A0A1B0GTI8 13 51813347-51845177 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 15.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "amygdala: 4.2;basal ganglia: 15.9;cerebral cortex: 10.0" "Immune cell enriched" "Detected in single" 89 "neutrophil: 40.1" "Lineage enriched" "Detected in single" 89 "granulocytes: 40.1" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.6" "Low region specificity" "Detected in many" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (2.27e-2)" "unprognostic (2.50e-1)" "unprognostic (5.12e-2)" "unprognostic (8.71e-7)" "unprognostic (4.52e-2)" "unprognostic (1.78e-4)" "unprognostic (6.16e-2)" "unprognostic (5.19e-2)" "unprognostic (8.88e-2)" "unprognostic (2.02e-1)" "unprognostic (3.73e-3)" "unprognostic (1.32e-5)" "unprognostic (2.12e-2)" "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.45e-1)" "unprognostic (1.58e-2)" 0.1 0.0 4.2 1.0 15.9 1.0 0.1 1.1 10.0 0.0 0.0 0.1 0.4 0.3 0.1 0.1 0.0 0.2 1.8 2.1 1.7 0.1 0.3 0.1 1.1 0.5 1.1 0.1 0.4 0.0 0.6 0.2 0.6 0.0 0.1 2.9 0.1 0.0 0.5 0.6 0.5 0.0 0.2 0.6 0.1 0.5 2.0 0.7 0.0 0.4 0.9 0.0 0.0 1.1 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 40.1 0.0 0.0 0.0 0.0 0.0 4.2 15.9 1.1 10.0 2.1 1.7 0.5 1.1 0.6 0.2 2.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM81 "HC3107, KVLA2788, MGC75217, UNQ2788" ENSG00000174529 "Transmembrane protein 81" Q6P7N7 1 205083129-205084460 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Early spermatids: 15.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052515 Approved "Intermediate filaments" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Intermediate filaments" "HPA052515: AB_2681858" "unprognostic (9.19e-3)" "unprognostic (3.53e-1)" "unprognostic (1.91e-3)" "unprognostic (6.48e-2)" "unprognostic (2.44e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (3.25e-6)" "unprognostic (3.66e-2)" "unprognostic (2.68e-2)" "unprognostic (6.18e-2)" "unprognostic (5.86e-2)" "unprognostic (2.48e-2)" "prognostic unfavorable (6.65e-9)" "unprognostic (8.91e-2)" "unprognostic (6.24e-2)" "unprognostic (2.42e-1)" "prognostic favorable (2.67e-4)" 2.3 3.7 8.8 1.1 9.1 1.5 1.8 11.5 12.4 4.0 8.1 2.7 0.9 2.4 2.0 2.8 2.7 0.8 4.1 9.1 8.8 4.4 6.0 2.9 1.7 8.7 8.7 4.0 2.5 1.5 3.9 1.3 8.7 3.7 1.1 4.3 2.1 1.3 6.6 3.7 2.6 1.1 8.5 5.4 2.6 5.8 9.4 3.2 2.8 2.4 1.7 2.7 3.3 9.6 1.8 2.8 4.6 6.0 6.6 2.6 2.3 3.4 2.0 1.7 1.0 5.0 1.2 3.4 2.4 1.9 2.5 1.6 7.5 2.8 3.0 3.0 2.9 2.9 3.8 2.5 4.5 1.5 1.5 2.6 5.1 2.7 1.3 4.5 3.4 4.0 6.5 1.4 2.2 3.6 3.4 6.3 3.5 2.3 4.0 2.3 5.3 3.6 4.0 1.8 2.9 4.5 2.1 2.5 5.6 7.1 1.9 6.2 1.6 3.2 1.6 4.1 3.7 3.2 4.2 2.7 4.5 2.2 5.5 1.7 0.4 0.0 1.8 0.6 0.0 0.6 0.8 0.4 0.6 0.5 0.8 1.4 1.0 0.0 0.6 0.6 1.1 0.4 8.8 9.1 11.5 12.4 9.1 8.8 8.7 8.7 8.7 8.5 9.4 9.6 0.5 0.0 0.0 2.0 0.7 2.3 0.5 0.6 0.0 0.8 1.6 1.4 2.0 1.5 0.4 3.7 0.0 0.2 1.6 0.8 0.0 0.7 15.6 1.1 0.6 0.9 0.0 0.0 2.0 0.6 0.5 0.6 0.0 1.3 0.0 2.3 0.4 1.0 0.6 1.7 1.5 0.5 2.0 0.3 2.1 3.1 0.0 0.9 1.8 1.0 0.4 1.4 3.1 1.0 1.3 0.8 0.1 0.4 1.3 1.2 0.4 1.3 0.5 1.1 0.0 1.0 0.6 0.9 1.1 0.5 2.6 0.1 0.9 0.4 0.6 1.0 TNFRSF14 "ATAR, CD270, HVEA, HVEM, LIGHTR, TR2" ENSG00000157873 "TNF receptor superfamily member 14" Q92956 1 2555639-2565382 "Cancer-related genes, CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 16.2" "Low region specificity" "Detected in all" "HPA006404, CAB026150, CAB030007" Approved NA NA 110000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "CAB026150: , CAB030007: AB_2303380, HPA006404: AB_1851348" "prognostic favorable (4.39e-5)" "unprognostic (3.48e-2)" "unprognostic (1.53e-2)" "prognostic favorable (8.01e-6)" "unprognostic (1.11e-2)" "unprognostic (6.83e-3)" "unprognostic (9.62e-3)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (1.62e-1)" "unprognostic (2.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.86e-2)" "unprognostic (1.16e-2)" "unprognostic (2.72e-2)" "unprognostic (1.58e-1)" "prognostic favorable (7.79e-6)" 37.0 71.8 2.4 6.2 2.2 5.0 34.8 2.2 6.6 52.5 3.9 57.6 16.9 32.9 1.2 26.4 39.9 4.4 23.8 2.7 2.4 57.1 61.8 58.0 10.0 2.6 2.3 33.0 20.4 3.9 24.4 2.8 2.4 50.4 5.5 0.6 35.3 2.3 6.5 22.2 67.5 1.2 2.1 100.7 45.9 7.5 2.7 2.8 29.4 1.0 4.0 33.6 37.3 2.6 0.6 0.3 0.3 8.7 2.3 9.1 2.7 2.5 8.5 4.9 6.5 0.7 6.3 2.4 0.5 7.7 2.8 4.4 0.0 3.2 0.7 11.4 0.0 6.1 0.8 1.0 9.1 3.3 6.8 4.4 2.6 2.6 0.6 4.3 5.8 0.4 1.9 11.9 4.5 0.0 4.4 0.3 0.1 2.4 4.4 2.8 0.0 0.6 0.4 3.7 0.1 0.2 0.0 0.4 16.2 0.0 1.5 0.7 5.9 0.3 1.8 0.8 0.4 8.1 2.2 1.2 0.5 2.7 1.5 2.2 31.4 5.5 40.2 68.2 23.3 42.4 47.2 27.0 23.2 50.1 51.3 39.4 78.4 12.8 50.9 33.2 62.8 39.3 2.4 2.2 2.2 6.6 2.7 2.4 2.6 2.3 2.4 2.1 2.7 2.6 63.7 19.2 38.0 5.5 97.6 16.4 31.2 50.3 23.3 1.5 36.0 33.8 8.3 47.1 51.5 35.0 0.0 1.2 90.9 94.7 3.9 16.8 0.3 19.9 18.4 52.7 36.1 18.7 8.8 32.9 1.5 27.1 77.5 25.8 53.2 8.3 41.4 20.0 88.8 0.0 0.9 78.4 22.4 80.1 59.3 2.6 20.8 91.3 46.2 17.8 106.1 15.9 131.8 2.5 1.3 24.6 115.8 13.9 70.4 29.8 219.6 35.5 34.7 0.7 19.7 9.0 22.0 0.1 0.4 15.6 13.4 1.2 84.4 16.0 101.4 44.3 TNFRSF19 "TAJ, TAJ-alpha, TRADE, TROY" ENSG00000127863 "TNF receptor superfamily member 19" Q9NS68 13 23570370-23676104 "Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 55.3;skin 1: 107.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.2;Microglial cells: 71.2;Respiratory ciliated cells: 62.4;Suprabasal keratinocytes: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 46.5;BJ hTERT+: 73.2;fHDF/TERT166: 55.9;Hep G2: 83.0;SK-MEL-30: 128.4;WM-115: 76.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010135 Approved Nucleoplasm,Mitochondria No No "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 28: Keratinocytes - Keratinization" Mitochondria Nucleoplasm "HPA010135: AB_1079797" "unprognostic (5.70e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.86e-3)" "unprognostic (2.01e-2)" "prognostic favorable (3.87e-4)" "unprognostic (3.74e-1)" "unprognostic (5.47e-2)" "unprognostic (4.41e-2)" "unprognostic (6.56e-2)" "prognostic favorable (9.13e-7)" "unprognostic (3.44e-2)" "unprognostic (6.05e-2)" "unprognostic (3.25e-3)" "unprognostic (5.38e-3)" 1.8 2.9 1.8 0.9 1.7 1.7 9.9 1.8 1.9 7.0 4.2 2.4 1.8 8.6 13.4 9.4 30.5 3.4 22.1 2.0 2.5 15.7 1.1 17.2 0.7 3.3 3.2 2.7 2.8 0.9 8.5 8.4 2.6 27.4 1.9 4.7 55.3 7.6 2.4 107.5 1.3 3.0 3.1 5.1 5.4 2.2 2.7 6.7 3.4 2.1 1.8 4.5 4.8 2.5 0.1 3.3 3.2 0.0 4.7 46.5 3.5 3.7 73.2 2.0 2.8 23.6 0.1 0.0 0.0 55.9 0.5 0.1 3.3 2.9 3.6 0.0 2.9 0.6 2.4 83.0 2.2 0.2 0.9 22.5 0.7 23.1 0.3 1.5 0.1 0.0 0.1 0.0 13.2 1.1 0.0 0.1 2.3 29.7 5.1 0.0 13.6 0.0 8.4 0.4 30.9 4.9 0.1 0.0 128.4 3.4 0.0 0.3 0.0 11.5 0.5 0.1 3.5 0.0 0.1 0.0 4.5 0.1 76.2 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 1.8 1.7 1.8 1.9 2.0 2.5 3.3 3.2 2.6 3.1 2.7 2.5 3.1 0.0 20.8 1.0 0.2 62.2 3.0 2.0 23.9 0.8 6.3 2.9 23.4 2.8 9.3 9.2 8.4 0.1 0.3 0.1 0.0 11.1 1.7 10.4 4.4 5.1 0.0 0.0 6.9 1.0 0.0 14.4 2.6 3.9 1.3 0.5 0.0 0.5 0.1 0.0 6.7 0.0 6.1 0.0 8.5 1.0 11.5 0.2 14.2 71.2 0.0 3.3 0.0 12.5 1.1 11.3 0.0 13.9 0.0 13.3 0.0 20.9 62.4 3.3 0.0 3.2 4.9 1.5 2.3 8.3 80.3 0.0 0.6 3.5 0.0 0.6 TOMM7 Tom7 ENSG00000196683 "Translocase of outer mitochondrial membrane 7" Q9P0U1 7 22812628-22822852 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 32: Non-specific - Translation" "unprognostic (6.69e-2)" "unprognostic (1.93e-1)" "unprognostic (4.91e-2)" "unprognostic (2.25e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (6.30e-4)" "unprognostic (2.25e-2)" "unprognostic (7.63e-2)" "unprognostic (1.52e-1)" "unprognostic (6.36e-2)" "unprognostic (2.49e-3)" "unprognostic (1.36e-1)" "unprognostic (1.75e-1)" "unprognostic (3.69e-3)" "unprognostic (2.08e-1)" "unprognostic (3.86e-2)" "unprognostic (1.01e-2)" 573.8 563.3 949.6 275.4 981.1 502.7 881.7 958.2 1282.5 678.2 985.2 739.2 356.5 495.5 537.9 428.7 587.3 242.1 701.6 934.9 962.7 495.7 491.2 443.6 496.2 956.1 949.0 973.9 682.7 523.2 539.2 248.2 953.4 481.8 421.2 419.1 527.3 508.3 1753.2 585.5 466.8 408.5 979.2 484.0 554.7 223.6 972.7 428.0 390.2 1299.3 674.7 524.7 524.5 979.0 712.5 403.3 257.7 530.0 951.1 1090.9 303.8 501.7 813.4 382.9 337.6 295.1 454.1 556.3 592.0 704.4 1148.1 457.9 672.4 540.6 415.7 303.3 695.0 269.6 942.9 386.3 811.1 638.0 289.4 1368.6 1222.6 575.7 862.1 1434.9 637.3 418.4 951.4 470.7 696.7 572.4 335.1 899.0 900.4 1002.6 960.5 282.0 302.0 782.7 353.7 367.6 241.7 416.3 367.6 886.3 1339.5 1009.6 658.7 1079.9 405.1 292.7 469.8 533.7 578.4 969.8 1141.0 783.5 389.4 658.3 1061.3 264.1 588.8 556.9 665.4 489.8 831.8 1233.9 1126.6 806.9 566.8 1053.9 1488.5 1059.0 199.4 567.6 525.1 868.7 919.5 1759.4 949.6 981.1 958.2 1282.5 934.9 962.7 956.1 949.0 953.4 979.2 972.7 979.0 483.9 259.6 350.4 25.1 883.6 886.1 805.5 698.9 570.8 279.7 998.5 1129.9 1223.2 622.0 372.1 349.4 66.7 477.2 670.5 558.3 1328.5 434.1 385.9 473.8 382.6 503.8 531.4 351.7 13.3 935.5 735.0 535.1 270.1 386.9 504.1 461.8 745.0 1228.2 699.6 151.4 12.7 1021.7 280.8 934.6 818.0 344.0 993.2 536.6 788.0 12.2 781.9 1059.7 784.8 8.5 19.5 534.9 823.7 759.8 360.8 828.6 1052.8 1386.2 362.6 311.9 486.4 996.5 557.8 448.0 204.1 691.9 926.6 406.1 811.4 292.2 879.5 820.9 TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205317-66420543 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 76.5;Excitatory neurons: 101.9;Inhibitory neurons: 107.1;Spermatocytes: 97.1" "Cancer enhanced" "Detected in all" "glioma: 36.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 52.2;neutrophil: 35.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: AB_2732672" "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavorable (8.16e-6)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.73e-5)" 16.9 15.8 22.1 10.8 20.5 6.0 13.4 18.4 21.6 35.4 12.3 11.1 3.2 21.8 14.3 10.8 11.2 38.1 8.5 19.4 36.7 23.1 46.0 11.5 5.9 37.2 25.0 13.5 7.8 11.0 19.5 26.4 24.7 15.1 8.0 5.2 6.8 16.4 2.7 8.2 8.7 16.2 22.9 12.0 10.9 23.0 33.8 2.1 11.3 5.6 5.3 36.8 22.1 22.5 12.1 6.5 16.5 22.4 52.7 42.0 5.7 22.3 49.8 25.7 37.1 21.9 6.6 1.4 17.7 45.1 38.9 8.9 16.2 24.8 33.3 3.5 9.3 2.3 15.1 16.5 62.3 1.8 1.9 59.5 19.0 50.2 22.1 27.8 32.7 2.9 1.0 10.2 40.2 6.2 0.1 3.1 15.5 0.4 9.6 7.8 14.6 11.4 27.3 11.5 10.4 44.5 27.8 2.1 62.2 32.4 8.6 4.7 62.3 33.1 21.3 24.2 40.6 9.2 13.3 4.7 29.6 6.8 48.2 52.2 2.3 23.9 0.8 0.1 0.8 6.1 0.5 0.6 0.3 14.0 2.2 4.1 35.2 8.8 0.0 0.0 0.0 1.9 22.1 20.5 18.4 21.6 19.4 36.7 37.2 25.0 24.7 22.9 33.8 22.5 33.8 0.0 8.9 38.8 11.5 10.8 7.7 24.4 33.6 8.5 4.0 13.3 1.6 5.7 9.6 31.3 2.1 1.8 3.8 0.2 9.8 23.0 11.2 13.3 76.5 17.9 7.7 1.3 101.9 47.6 4.3 58.5 12.2 9.7 4.5 12.2 10.0 34.1 16.2 6.7 107.1 0.8 8.2 8.9 8.9 11.6 48.1 6.2 14.2 32.8 15.8 5.0 1.0 61.3 38.8 23.7 0.1 37.2 7.1 5.3 0.0 3.2 19.5 3.6 6.6 16.4 21.6 97.1 41.3 15.1 7.5 3.8 2.8 12.6 0.7 7.7 TRAK2 "ALS2CR3, CALS-C, GRIF-1, KIAA0549, MILT2, OIP98" ENSG00000115993 "Trafficking kinesin protein 2" O60296 2 201377207-201451500 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 157.8;Erythroid cells: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015827, HPA062163" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Nuclear bodies" Vesicles "HPA015827: AB_1858238, HPA062163: AB_2684702" "unprognostic (2.10e-1)" "unprognostic (1.39e-1)" "unprognostic (2.56e-2)" "unprognostic (4.31e-2)" "unprognostic (2.78e-1)" "unprognostic (1.76e-1)" "unprognostic (2.38e-2)" "unprognostic (3.08e-2)" "unprognostic (2.24e-1)" "unprognostic (1.76e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-1)" "prognostic favorable (7.42e-5)" "unprognostic (1.48e-1)" "unprognostic (3.24e-1)" "unprognostic (1.40e-2)" "unprognostic (9.82e-3)" 24.1 20.3 53.2 16.4 63.7 52.2 14.8 61.2 60.9 16.1 55.6 22.4 13.4 14.3 13.0 16.7 13.9 18.7 70.9 47.3 54.0 23.7 14.1 20.7 17.3 92.9 67.6 9.7 15.4 26.6 12.4 23.7 86.8 12.8 22.8 20.1 26.4 15.2 14.8 8.1 16.1 20.4 99.9 18.1 12.2 7.8 69.7 12.4 34.9 26.8 13.6 15.7 9.0 102.2 11.6 15.5 9.4 34.3 61.6 87.4 10.6 39.2 32.8 27.4 31.9 24.4 9.8 7.1 16.3 50.6 26.4 11.2 20.0 12.9 43.5 21.4 13.0 15.5 25.6 15.9 33.8 12.3 18.4 48.4 10.8 28.8 22.2 27.5 40.4 11.0 12.4 26.9 55.8 16.6 9.6 6.9 10.6 11.3 32.7 12.1 24.9 10.6 21.9 15.6 18.6 24.0 21.0 15.5 63.6 13.6 12.4 12.4 50.2 44.2 16.6 31.0 25.7 16.2 30.2 8.3 37.2 18.2 24.4 2.6 5.5 6.2 7.8 7.0 7.3 9.3 10.1 6.7 4.3 14.2 6.9 7.3 3.4 11.1 6.5 2.3 12.6 6.0 53.2 63.7 61.2 60.9 47.3 54.0 92.9 67.6 86.8 99.9 69.7 102.2 34.0 16.0 29.8 37.5 17.8 8.3 3.4 6.3 11.4 45.4 14.4 8.8 157.8 22.8 13.4 9.2 73.0 10.3 9.3 27.9 7.9 13.9 1.9 12.7 20.9 21.0 29.5 181.0 92.3 14.7 4.8 16.9 10.7 25.7 19.6 10.3 15.0 14.3 10.6 77.4 75.6 20.6 10.2 12.9 7.7 3.8 8.1 13.2 26.6 22.5 14.2 5.1 12.3 47.7 57.0 10.7 14.5 12.8 16.8 5.7 21.7 8.9 14.9 22.1 13.1 23.2 23.3 9.4 12.8 16.2 4.1 5.6 16.6 18.7 24.5 7.2 TRAPPC3 BET3 ENSG00000054116 "Trafficking protein particle complex 3" O43617 1 36136570-36156053 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028408 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Cytosol "Golgi apparatus" "HPA028408: AB_10601826" "unprognostic (3.54e-3)" "unprognostic (1.17e-1)" "unprognostic (1.36e-1)" "unprognostic (4.94e-2)" "unprognostic (2.88e-1)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.70e-6)" "unprognostic (7.39e-3)" "unprognostic (1.15e-1)" "unprognostic (7.12e-3)" "unprognostic (7.38e-2)" "unprognostic (2.94e-1)" "unprognostic (9.25e-3)" "unprognostic (2.61e-2)" "unprognostic (9.47e-2)" "unprognostic (2.10e-3)" "unprognostic (6.53e-2)" 43.7 74.7 42.5 31.2 43.0 28.8 46.6 47.0 50.7 38.5 53.7 57.0 33.6 41.1 60.7 61.6 37.0 32.6 51.1 43.1 44.9 55.3 51.2 36.4 38.3 48.0 45.1 28.2 46.0 54.4 47.0 37.8 47.2 39.2 42.5 39.9 46.4 45.4 48.9 51.5 38.5 49.9 48.3 41.6 48.2 53.1 46.3 51.3 59.9 44.6 54.4 46.2 41.2 48.9 95.7 65.6 44.9 70.2 114.2 91.4 87.9 85.2 109.0 100.0 97.0 55.9 90.0 40.4 79.0 95.0 79.6 68.8 69.9 114.1 113.8 79.8 103.7 75.8 77.2 81.7 132.6 80.0 76.7 78.3 98.5 93.8 91.5 103.6 126.7 101.2 93.2 67.0 122.0 71.4 95.6 74.6 60.5 79.5 93.7 65.8 63.8 90.9 128.4 76.1 67.8 49.7 69.2 78.5 140.1 115.2 50.2 59.6 95.6 59.1 66.7 116.0 116.3 80.1 87.0 67.3 100.7 88.7 60.5 161.9 130.2 148.7 85.0 142.5 89.4 93.6 100.4 90.4 132.6 89.0 96.0 86.9 134.3 95.8 116.3 109.4 135.4 155.3 42.5 43.0 47.0 50.7 43.1 44.9 48.0 45.1 47.2 48.3 46.3 48.9 41.9 25.6 27.6 12.1 45.6 101.1 111.5 152.1 52.3 41.8 97.8 78.5 57.8 55.8 75.7 38.6 16.7 145.7 43.0 55.1 170.2 157.0 286.1 51.8 38.3 59.1 48.3 63.3 15.4 188.5 146.0 52.1 29.0 55.6 45.7 40.5 33.2 49.8 145.0 53.8 16.9 51.2 132.2 56.1 74.7 131.0 42.9 60.6 96.0 10.3 104.4 68.0 61.8 8.5 17.9 178.4 72.1 51.9 80.7 196.9 73.3 115.9 49.2 30.7 32.9 37.4 69.2 172.5 89.4 63.4 123.6 191.4 50.4 50.3 54.3 134.1 TRIM2 "CMT2R, KIAA0517, RNF86" ENSG00000109654 "Tripartite motif containing 2" Q9C040 4 153152163-153339319 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 116.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1132.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 47.0;SK-MEL-30: 46.8" "HPA035853, HPA035854" Supported Uncertain Centrosome NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Centrosome "HPA035853: AB_10669533, HPA035854: AB_10669659" "unprognostic (8.94e-2)" "unprognostic (7.89e-2)" "unprognostic (6.21e-3)" "unprognostic (7.51e-3)" "unprognostic (2.07e-2)" "unprognostic (2.32e-1)" "unprognostic (1.16e-2)" "unprognostic (2.30e-3)" "unprognostic (5.30e-2)" "unprognostic (6.77e-2)" "unprognostic (1.93e-2)" "unprognostic (1.42e-2)" "prognostic favorable (6.58e-14)" "unprognostic (5.89e-2)" "unprognostic (1.17e-2)" "unprognostic (4.19e-2)" "unprognostic (4.13e-2)" 5.8 11.8 29.5 4.8 64.4 0.1 11.8 38.6 46.2 23.6 0.0 21.6 17.4 9.9 8.0 10.7 15.2 12.6 8.4 48.0 34.8 24.2 7.9 7.2 2.2 40.1 33.2 12.8 12.7 1.0 21.6 2.5 56.3 13.1 19.3 19.4 42.9 13.4 2.1 7.1 17.3 7.0 35.3 10.6 27.4 1.9 37.9 2.9 50.6 3.0 3.9 12.0 11.5 116.2 10.2 0.2 47.0 24.2 22.0 27.2 0.5 12.7 15.4 3.6 4.5 4.1 0.2 0.1 7.7 21.7 8.5 6.4 24.7 4.7 3.2 0.0 5.4 0.1 4.6 0.5 24.7 0.1 0.1 13.5 2.3 5.4 4.7 12.9 3.4 0.4 0.2 0.0 4.9 0.4 2.4 0.1 37.4 27.5 8.8 1.0 9.4 0.0 37.0 11.8 14.5 27.3 4.4 2.7 46.8 6.9 1.7 0.5 2.8 12.7 3.0 10.8 3.9 0.0 0.0 0.1 20.9 0.0 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.1 29.5 64.4 38.6 46.2 48.0 34.8 40.1 33.2 56.3 35.3 37.9 116.2 11.2 6.4 33.7 189.0 2.6 7.0 15.3 40.2 9.1 67.7 40.5 29.1 39.6 17.2 82.1 58.8 29.2 2.0 0.7 59.4 101.8 9.6 3.3 113.3 16.3 17.3 62.3 0.4 266.4 26.1 0.5 22.0 80.0 95.6 1.3 4.8 21.0 12.4 1.4 111.0 211.2 64.1 54.9 0.8 7.7 2.4 29.5 2.2 64.0 21.5 3.2 86.9 0.0 237.2 1132.8 22.5 41.4 32.7 1.5 17.8 62.9 14.7 106.0 23.4 26.3 14.7 16.2 0.4 1.3 5.0 4.0 0.7 2.8 8.7 90.8 33.7 TRIM51 "SPRYD5, TRIM51A" ENSG00000124900 "Tripartite motif-containing 51" Q9BSJ1 11 55883297-55891810 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 50 "melanoma: 4.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 112 "basophil: 11.2" "Lineage enriched" "Detected in single" 112 "granulocytes: 11.2" "Cell line enriched" "Detected in some" 4 "SK-MEL-30: 61.3" "HPA044988, HPA077883" Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" Vesicles Nucleoli "HPA044988: AB_2679171, HPA077883: AB_2732362" "unprognostic (9.60e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIM51GP ENSG00000220948 "Tripartite motif-containing 51G, pseudogene" 11 48975324-48983826 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.1" "HPA044988, HPA077883" Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 33: SK-MEL-30 - Melanocyte processes" Vesicles Nucleoli "HPA044988: AB_2679171, HPA077883: AB_2732362" "unprognostic (2.95e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIM62 "DEAR1, FLJ10759" ENSG00000116525 "Tripartite motif containing 62" Q9BVG3 1 33145399-33182059 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 21.0" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "AF22: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050061 Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" "Vesicles, Focal adhesion sites" "HPA050061: AB_2681001" "unprognostic (1.57e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (2.62e-2)" "unprognostic (1.14e-2)" "unprognostic (5.80e-2)" "unprognostic (5.10e-5)" "unprognostic (2.05e-2)" "unprognostic (1.14e-1)" "unprognostic (4.32e-2)" "unprognostic (3.55e-3)" "unprognostic (3.66e-1)" "prognostic unfavorable (7.08e-5)" "unprognostic (2.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (2.05e-3)" 3.1 6.6 8.7 2.9 13.1 4.8 3.6 10.0 11.9 3.2 2.3 3.2 2.4 3.1 2.6 5.1 3.0 2.0 3.5 8.5 10.4 3.5 1.8 3.1 4.6 10.7 11.3 3.7 3.1 2.9 6.4 3.4 12.1 5.1 2.1 2.1 5.2 2.9 4.9 12.5 4.2 2.8 7.4 5.1 4.3 2.3 12.4 5.2 3.9 2.5 4.5 4.8 4.4 21.0 3.7 2.7 23.9 3.9 5.7 2.5 7.6 3.4 9.9 6.3 5.5 3.0 3.7 5.9 3.8 3.0 3.2 7.2 5.0 4.3 5.6 5.8 3.8 6.5 3.2 2.5 5.7 2.2 16.2 5.2 3.9 8.7 2.0 9.9 6.3 5.0 1.1 3.8 6.1 9.9 6.8 2.0 6.0 4.3 3.5 8.6 12.8 2.7 3.8 9.6 6.0 3.7 3.8 14.5 16.8 12.6 4.1 1.4 6.3 2.7 3.8 8.1 2.8 6.9 3.3 2.7 5.1 3.9 3.5 1.2 1.0 3.4 1.3 1.8 2.3 1.1 1.9 1.8 0.9 1.4 1.3 1.2 2.3 1.0 1.1 0.4 4.7 1.1 8.7 13.1 10.0 11.9 8.5 10.4 10.7 11.3 12.1 7.4 12.4 21.0 2.0 3.2 2.2 2.6 1.8 2.7 0.8 1.7 2.8 3.4 3.5 1.9 0.9 0.0 1.2 1.8 0.0 1.1 2.5 1.5 0.0 1.4 0.5 0.6 1.1 1.4 1.8 0.4 1.9 1.9 1.8 2.1 4.1 1.3 1.3 1.7 1.1 0.7 1.2 10.1 10.2 1.5 4.1 1.2 1.6 0.5 2.5 1.3 0.0 10.3 1.4 1.5 3.1 50.8 26.0 2.6 0.6 4.9 2.6 2.1 1.2 1.0 0.4 1.0 6.6 2.0 2.1 1.3 0.6 2.8 4.7 1.4 3.0 3.4 0.9 2.0 TRIM63 "IRF, MURF-1, RNF28, SMRZ" ENSG00000158022 "Tripartite motif containing 63" Q969Q1 1 26051301-26068436 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Muscle protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 1935.8" "Cell type enriched" "Detected in some" 7 "Cardiomyocytes: 272.2" "Cancer enriched" "Detected in some" 10 "melanoma: 31.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "ASC diff: 16.1;SK-MEL-30: 55.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 5.1" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.10e-1)" "unprognostic (4.80e-4)" "unprognostic (1.45e-2)" "unprognostic (7.52e-3)" "unprognostic (1.44e-1)" "unprognostic (2.05e-2)" "unprognostic (3.42e-1)" "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (1.06e-1)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (2.16e-2)" "unprognostic (5.90e-2)" "unprognostic (1.33e-2)" "unprognostic (2.32e-1)" "unprognostic (5.58e-2)" 1.2 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.1 1.5 0.0 0.7 0.3 8.8 0.3 7.1 0.6 2.7 243.0 0.0 0.0 1.5 0.4 1.3 0.0 0.1 0.1 0.2 0.8 0.0 0.2 4.0 0.0 1.5 0.2 0.1 9.6 0.4 1935.8 4.2 0.8 3.5 0.0 0.2 0.8 0.2 0.2 0.3 0.5 387.6 0.2 8.9 1.1 0.1 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.0 272.2 5.7 0.0 1.8 0.0 0.5 0.0 0.0 1.9 1.8 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.1 8.1 0.0 0.1 10.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 12.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 3.3 29.7 0.0 0.0 0.0 34.7 1.4 0.0 0.0 0.0 0.1 1.6 6.1 0.0 0.1 0.1 TRPM1 "CSNB1C, LTRPC1, MLSN1" ENSG00000134160 "Transient receptor potential cation channel subfamily M member 1" Q7Z4N2 15 31001061-31161273 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 9.4;skin 1: 4.1" "Group enriched" "Detected in some" 7 "Bipolar cells: 627.4;Melanocytes: 158.3" "Cancer enriched" "Detected in single" 179 "melanoma: 14.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 112 "SK-MEL-30: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014779, HPA071139" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" "Centriolar satellite" "Golgi apparatus, Plasma membrane" "HPA014779: AB_2669090, HPA071139: " "unprognostic (5.28e-2)" "unprognostic (1.35e-1)" "unprognostic (9.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (1.29e-3)" "unprognostic (2.83e-1)" "unprognostic (2.89e-2)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (7.84e-2)" "unprognostic (6.20e-4)" "unprognostic (1.48e-1)" "unprognostic (2.63e-2)" 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.4 0.1 0.0 0.0 4.1 0.0 0.0 0.5 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.1 0.2 0.2 0.4 0.3 0.5 0.3 0.5 0.0 0.0 0.0 0.7 0.0 4.2 0.0 0.0 0.0 627.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 50.5 0.1 0.1 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 13.5 0.8 0.0 0.0 0.0 1.0 6.3 0.0 0.0 158.3 0.0 0.0 11.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 22.2 0.0 0.1 0.1 10.1 4.4 1.8 1.0 1.0 0.0 0.0 0.0 0.1 TRPM8 ENSG00000144481 "Transient receptor potential cation channel subfamily M member 8" Q7Z2W7 2 233917373-234019522 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 57 "liver: 31.5;prostate: 80.2" "Group enriched" "Detected in some" 5 "Hepatocytes: 45.2;Prostatic glandular cells: 16.3" "Cancer enriched" "Detected in some" 27 "prostate cancer: 72.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 3.4;Karpas-707: 5.5;RPTEC TERT1: 8.1;SK-MEL-30: 8.9;WM-115: 5.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (4.41e-3)" "unprognostic (7.91e-2)" "unprognostic (1.11e-1)" "unprognostic (5.49e-3)" "unprognostic (1.05e-1)" "unprognostic (4.60e-3)" "prognostic favorable (7.15e-4)" "unprognostic (3.28e-2)" "unprognostic (3.71e-1)" "unprognostic (9.88e-3)" "unprognostic (7.10e-3)" "unprognostic (4.69e-2)" "unprognostic (3.36e-5)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (5.53e-2)" 0.0 0.2 0.2 0.2 0.3 0.1 0.0 0.3 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.1 31.5 0.0 0.1 0.1 0.9 0.0 0.0 0.1 0.5 0.0 0.3 80.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.2 0.4 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.6 8.1 0.0 0.5 0.3 0.0 0.1 8.9 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.0 1.2 2.0 0.0 0.7 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.3 0.3 0.1 0.9 0.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.4 5.5 0.1 0.0 0.7 0.2 0.0 1.1 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 2.3 1.2 0.6 0.5 0.0 2.7 0.3 1.7 0.0 0.3 0.0 4.4 0.0 0.1 0.7 45.2 0.3 0.0 0.9 0.0 0.0 0.6 0.8 3.9 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 16.3 0.0 0.0 0.0 0.2 0.0 0.4 0.2 1.3 0.6 0.0 0.1 0.0 0.5 0.0 0.0 4.1 TSPAN10 OCSP ENSG00000182612 "Tetraspanin 10" 17 81637171-81648749 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Collecting duct cells: 12.9;Horizontal cells: 13.5" "Cancer enriched" "Detected in many" 15 "melanoma: 32.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 17.8;U-138 MG: 6.0;U-87 MG: 7.6" "Region enriched" "Detected in single" 4 "olfactory bulb: 1.3" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.81e-2)" "unprognostic (3.67e-1)" "unprognostic (2.17e-3)" "unprognostic (1.08e-3)" "unprognostic (3.74e-1)" "unprognostic (3.48e-2)" "unprognostic (1.55e-1)" "unprognostic (1.26e-1)" "unprognostic (2.33e-1)" "unprognostic (1.95e-1)" "unprognostic (5.59e-3)" "unprognostic (1.21e-1)" "unprognostic (1.01e-1)" "unprognostic (2.43e-2)" "unprognostic (7.31e-2)" "unprognostic (2.81e-1)" "unprognostic (1.58e-1)" 0.5 1.2 0.1 0.2 0.1 0.0 0.6 0.2 0.2 1.0 0.6 0.2 0.1 0.7 0.4 0.8 0.7 0.3 0.2 0.0 0.3 1.0 0.9 0.3 0.9 0.1 0.1 0.8 0.7 0.6 0.3 0.5 0.2 1.2 0.0 0.0 0.9 0.3 0.0 1.3 0.3 0.0 0.1 0.4 0.3 1.2 0.1 0.3 0.6 0.0 0.2 0.3 0.5 0.1 1.8 1.9 0.2 0.2 0.5 0.6 0.2 1.8 5.7 2.7 1.5 0.6 3.0 0.7 0.6 1.7 1.5 0.0 0.1 0.4 0.3 0.6 3.4 0.0 0.4 0.4 0.4 0.0 1.0 0.6 0.7 3.2 0.1 5.8 0.0 0.7 0.0 0.2 2.7 0.2 0.1 0.4 0.2 0.0 2.8 1.3 0.0 0.0 0.2 0.5 0.0 1.2 3.1 0.4 17.8 1.5 3.4 0.4 0.1 6.0 1.9 0.5 1.6 0.0 0.0 0.0 7.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.3 0.1 0.1 0.2 0.1 0.1 0.1 3.0 3.2 7.3 0.7 2.1 0.0 2.6 0.0 0.6 2.5 5.1 6.3 1.8 4.3 2.5 12.9 4.2 2.1 1.1 1.7 9.8 3.6 0.9 3.4 2.1 2.9 0.0 0.8 0.5 2.4 6.2 3.2 1.5 4.4 7.6 3.3 3.6 1.5 10.0 13.5 0.5 1.2 0.0 1.6 0.0 2.1 1.5 2.3 0.0 2.8 0.0 5.4 0.0 0.5 1.7 0.9 0.1 1.2 0.0 1.7 1.1 4.5 3.6 5.0 0.0 3.6 1.7 5.7 5.8 1.2 0.0 1.4 1.3 8.6 1.1 1.3 TTC19 "FLJ20343, MGC19520" ENSG00000011295 "Tetratricopeptide repeat domain 19" Q6DKK2 17 15999784-16045015 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023010, HPA052380" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA023010: AB_1858429, HPA052380: AB_2681806" "unprognostic (1.04e-2)" "unprognostic (4.90e-3)" "unprognostic (2.87e-2)" "unprognostic (4.80e-3)" "unprognostic (8.09e-2)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.84e-2)" "unprognostic (8.34e-2)" "unprognostic (1.72e-2)" "unprognostic (2.30e-3)" "unprognostic (5.14e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.31e-1)" "unprognostic (3.22e-1)" "unprognostic (4.85e-2)" "unprognostic (2.24e-1)" 6.6 11.4 8.1 3.8 7.8 11.2 7.5 19.4 11.6 6.9 8.4 8.0 10.3 6.9 5.2 6.8 5.8 5.2 8.6 8.8 9.6 8.7 7.7 6.6 4.6 7.9 7.4 6.9 12.4 11.2 8.0 5.8 7.9 6.8 5.7 9.9 9.1 4.2 8.8 9.5 9.8 3.8 6.3 4.5 8.4 3.6 8.0 3.9 10.6 4.4 3.3 6.3 6.7 10.5 7.0 4.1 7.6 12.1 6.4 5.6 4.0 3.1 4.6 3.1 3.8 6.5 12.8 8.9 9.8 4.3 4.6 9.1 9.9 8.3 3.8 12.5 10.2 8.2 9.2 6.3 9.1 9.3 11.6 5.6 7.0 2.6 11.4 9.6 7.1 12.4 4.6 7.7 6.8 7.6 7.5 6.8 10.0 11.8 3.0 7.8 8.0 8.2 11.6 10.5 6.6 5.5 7.6 9.8 16.6 24.6 6.9 4.6 13.1 4.2 1.2 6.1 7.5 4.8 1.5 4.2 9.8 9.8 9.5 5.2 0.7 1.8 0.7 0.7 1.2 0.9 0.9 1.2 0.7 1.1 1.0 1.3 0.7 0.6 0.7 1.1 1.0 0.4 8.1 7.8 19.4 11.6 8.8 9.6 7.9 7.4 7.9 6.3 8.0 10.5 51.0 41.7 38.6 69.5 60.8 105.3 83.5 30.8 70.6 147.8 65.1 47.9 34.8 42.9 35.4 46.0 143.9 75.7 62.8 59.7 70.5 50.0 59.4 49.4 41.5 60.3 45.6 32.4 115.1 41.2 41.9 34.2 43.8 67.9 31.1 46.8 42.8 36.0 25.6 129.5 100.9 52.3 26.4 25.8 76.7 7.2 41.0 46.5 55.2 35.6 34.8 73.9 70.0 54.3 57.8 47.7 57.9 33.4 34.5 89.1 75.4 47.1 26.5 180.4 46.0 56.5 40.2 30.2 31.1 56.9 116.8 65.5 68.9 69.9 63.3 72.7 TTL MGC46235 ENSG00000114999 "Tubulin tyrosine ligase" Q8NG68 2 112482156-112541739 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066819 Approved Nucleoplasm,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "HPA066819: AB_2685728" "unprognostic (1.05e-2)" "unprognostic (3.90e-3)" "unprognostic (2.25e-1)" "unprognostic (3.95e-3)" "unprognostic (9.75e-2)" "unprognostic (1.81e-2)" "prognostic unfavorable (5.65e-4)" "unprognostic (2.95e-1)" "unprognostic (3.65e-1)" "unprognostic (2.10e-1)" "unprognostic (5.48e-2)" "unprognostic (7.19e-2)" "unprognostic (6.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.45e-1)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" 1.0 0.8 2.3 0.9 3.0 1.8 0.6 1.6 3.0 0.6 0.1 0.8 0.6 1.0 0.8 1.1 0.5 1.1 1.6 2.4 1.7 0.8 0.6 1.3 1.0 1.5 1.9 0.6 0.8 0.8 0.3 1.2 1.6 0.6 0.8 1.4 0.4 0.7 3.7 1.4 0.6 1.3 0.8 0.9 0.6 0.6 2.7 1.0 0.9 3.8 0.8 1.0 0.4 3.5 2.9 2.2 2.7 6.2 3.2 4.6 1.1 4.9 4.0 5.1 4.4 2.7 1.0 2.7 2.7 4.2 3.3 2.0 4.8 2.5 6.2 1.9 2.7 2.3 3.1 3.4 1.4 3.2 1.1 2.1 1.7 7.5 4.0 2.3 4.4 1.8 3.8 2.1 4.1 1.5 2.8 1.8 2.4 0.8 4.4 3.0 3.1 1.5 1.6 2.2 5.8 4.0 3.8 1.2 6.7 1.8 1.3 1.8 4.4 6.0 4.4 4.8 3.7 1.1 2.5 2.2 6.7 2.4 2.6 0.6 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.2 0.2 0.1 0.0 2.3 3.0 1.6 3.0 2.4 1.7 1.5 1.9 1.6 0.8 2.7 3.5 14.0 12.8 6.4 19.2 7.0 20.3 4.9 8.3 4.6 15.6 6.4 6.0 39.1 2.8 6.7 12.9 12.5 3.2 10.6 8.0 0.0 7.2 12.2 8.3 28.3 18.5 11.3 16.2 34.1 9.6 2.4 12.6 2.6 10.8 0.0 11.7 15.7 10.4 11.4 8.4 24.0 5.8 16.2 24.2 19.2 5.1 3.1 17.0 7.2 20.6 17.2 9.8 8.2 24.6 72.8 9.4 5.2 5.7 9.1 6.6 2.4 6.0 4.2 20.2 6.6 15.4 12.2 4.5 5.0 6.5 18.0 1.2 7.6 7.7 6.1 4.1 TTYH2 C17orf29 ENSG00000141540 "Tweety family member 2" Q9BSA4 17 74213571-74262020 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 214.5" "Cell type enhanced" "Detected in many" "Astrocytes: 46.0;Bipolar cells: 59.2;Langerhans cells: 52.1;Oligodendrocytes: 206.9" "Group enriched" "Detected in all" 6 "glioma: 16.7;melanoma: 20.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 13.3;intermediate monocyte: 22.3;myeloid DC: 14.6;non-classical monocyte: 28.6;plasmacytoid DC: 18.2" "Group enriched" "Detected in many" 5 "dendritic cells: 18.2;monocytes: 28.6" "Cell line enhanced" "Detected in many" "HSkMC: 22.2;SK-MEL-30: 81.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.19e-1)" "unprognostic (5.08e-1)" "unprognostic (1.58e-3)" "unprognostic (3.51e-4)" "unprognostic (1.59e-1)" "unprognostic (2.44e-1)" "unprognostic (1.67e-2)" "unprognostic (5.90e-2)" "unprognostic (8.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.81e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (9.74e-5)" "unprognostic (8.98e-3)" "unprognostic (5.70e-3)" "unprognostic (2.50e-3)" "unprognostic (3.51e-3)" 5.5 4.7 75.4 7.3 132.2 3.3 4.4 101.4 103.2 7.1 34.7 8.2 2.6 4.9 3.5 3.2 6.3 5.1 18.1 83.7 91.3 2.0 1.6 5.5 7.7 129.0 115.2 17.2 8.3 4.0 7.0 10.3 123.3 4.6 2.5 19.8 6.9 4.0 14.8 5.2 4.8 3.9 88.2 11.7 3.9 15.2 113.6 5.1 10.1 9.4 5.7 5.3 4.7 214.5 0.2 1.9 9.0 8.7 1.1 1.3 0.2 0.5 0.1 0.5 0.1 5.9 0.1 5.3 1.3 0.2 1.0 14.5 8.9 0.3 0.3 12.5 5.0 5.7 0.3 0.5 6.2 0.6 3.8 22.2 4.6 0.1 1.6 0.6 0.3 3.8 1.0 2.6 0.2 1.0 2.7 0.4 1.7 8.7 15.7 8.8 16.1 10.1 0.2 0.7 3.1 11.0 0.0 5.5 81.3 4.6 2.9 1.2 0.2 0.0 4.4 0.1 0.3 0.5 0.3 0.1 0.3 1.7 4.9 1.0 13.3 1.2 2.4 22.3 0.3 0.3 4.6 3.8 14.6 0.3 0.7 1.7 1.2 0.1 28.6 18.2 4.5 7.0 75.4 132.2 101.4 103.2 83.7 91.3 129.0 115.2 123.3 88.2 113.6 214.5 8.0 0.0 4.1 46.0 1.3 2.3 0.6 0.2 1.2 59.2 1.5 2.4 1.9 2.8 0.1 0.0 6.2 0.3 7.9 0.0 0.0 0.2 27.7 0.4 0.7 6.9 1.8 0.0 1.0 0.2 0.4 4.1 0.5 0.9 21.6 0.5 1.8 0.5 5.0 3.3 0.9 0.2 0.0 12.3 52.1 11.5 9.6 13.7 23.2 15.0 16.5 18.4 0.0 10.6 206.9 0.1 0.1 2.6 1.3 0.8 0.0 0.2 0.3 10.8 19.7 3.2 2.7 2.4 1.5 0.4 2.6 0.3 2.3 4.3 0.0 0.4 TUBB2A "dJ40E16.7, TUBB, TUBB2" ENSG00000137267 "Tubulin beta 2A class IIa" Q13885 6 3153497-3157544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 364.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 516.5;Suprabasal keratinocytes: 368.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.2;monocytes: 1.6;T-cells: 3.2" "Cell line enhanced" "Detected in all" "AF22: 241.1;CACO-2: 247.6;SuSa: 365.5;WM-115: 280.1" "Low region specificity" "Detected in all" "CAB015339, HPA043640, HPA046280" Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 61: Squamous epithelial cells - Keratinization" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB015339: AB_2210539, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.57e-1)" "unprognostic (9.86e-3)" "unprognostic (5.90e-3)" "unprognostic (7.98e-3)" "unprognostic (4.02e-3)" "unprognostic (1.67e-1)" "unprognostic (1.82e-3)" "unprognostic (7.53e-2)" "unprognostic (1.48e-3)" "unprognostic (9.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.42e-2)" "prognostic favorable (4.65e-4)" "unprognostic (2.39e-2)" "unprognostic (1.79e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (1.61e-4)" 58.8 17.8 266.1 19.3 251.1 67.5 47.8 130.1 287.5 32.7 10.0 78.0 24.2 50.8 28.0 90.6 23.5 21.5 29.4 248.3 364.3 31.1 67.0 16.4 11.0 292.6 212.2 15.5 39.4 2.2 56.3 23.9 334.3 17.5 8.2 49.9 52.2 15.6 22.3 151.4 34.9 41.7 131.6 7.7 41.0 9.5 204.4 6.4 10.0 11.8 9.6 23.6 51.2 169.4 55.9 45.3 241.1 53.6 30.6 34.0 14.5 119.8 44.7 80.6 115.7 247.6 18.4 27.4 72.9 115.5 80.2 26.0 86.6 26.8 28.0 134.1 57.7 9.4 11.4 77.0 31.6 1.5 8.4 35.1 31.1 85.1 5.3 28.9 37.3 10.6 33.7 8.8 74.2 25.1 14.9 2.8 207.2 16.0 58.3 12.4 22.6 18.9 28.0 27.4 57.6 52.9 30.5 8.5 179.7 365.5 19.1 2.0 76.0 53.9 56.7 117.3 65.8 3.2 4.6 18.8 19.7 7.0 280.1 0.0 1.1 0.0 2.2 1.6 2.4 3.2 2.1 3.1 0.5 0.6 1.0 2.0 0.3 0.4 1.3 0.2 3.2 1.2 266.1 251.1 130.1 287.5 248.3 364.3 292.6 212.2 334.3 131.6 204.4 169.4 125.3 16.0 13.1 43.1 31.6 311.4 63.3 87.0 132.6 105.6 32.0 134.6 20.4 42.9 62.7 12.9 16.7 6.0 53.4 87.0 217.2 54.0 60.9 46.7 29.6 40.6 73.1 322.3 59.9 182.4 50.4 96.2 185.0 57.9 34.9 10.1 12.5 55.6 50.8 516.5 73.0 103.9 73.2 6.3 164.4 32.9 20.8 36.7 129.9 24.4 72.7 261.0 0.0 18.1 23.0 103.4 181.8 15.4 15.8 34.9 126.3 40.4 50.3 86.2 6.6 95.6 87.9 32.4 14.9 140.6 368.5 6.2 58.9 6.4 60.0 54.7 TYR "OCA1, OCA1A, OCAIA" ENSG00000077498 Tyrosinase P14679 11 89177875-89295759 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase, Tumor antigen" "Albinism, Deafness, Disease variant, FDA approved drug targets, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "skin 1: 31.6" "Cell type enriched" "Detected in some" 5 "Melanocytes: 184.9" "Cancer enriched" "Detected in single" 1755 "melanoma: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 995 "SK-MEL-30: 426.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000079, HPA043241, HPA050889, HPA064583" Enhanced Enhanced Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "CAB000079: AB_564045, HPA043241: AB_2678383, HPA050889: AB_2681264, HPA064583: " "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-3)" "unprognostic (9.75e-3)" 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 31.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 426.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.9 0.3 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.5 5.2 0.3 0.0 184.9 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.0 0.0 0.1 0.0 0.0 0.0 TYRP1 "b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP" ENSG00000107165 "Tyrosinase related protein 1" P17643 9 12685439-12710285 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 44.8;heart muscle: 59.9;skin 1: 145.0" "Cell type enriched" "Detected in some" 17 "Melanocytes: 2486.6" "Cancer enriched" "Detected in some" 262 "melanoma: 313.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 55 "SK-MEL-30: 1395.0" "Group enriched" "Detected in some" 5 "olfactory bulb: 4.6;thalamus: 1.8" "Low region specificity" "Detected in all" "HPA000937, CAB002520" Enhanced Approved Vesicles NA NA 51000 "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB002520: AB_564153, HPA000937: AB_1080437" "unprognostic (7.48e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-1)" "unprognostic (3.16e-3)" "unprognostic (8.10e-2)" "unprognostic (3.82e-3)" "unprognostic (1.53e-1)" "unprognostic (2.25e-3)" "unprognostic (4.46e-1)" "unprognostic (8.71e-2)" "unprognostic (6.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.68e-6)" "unprognostic (1.27e-1)" "unprognostic (5.99e-2)" "unprognostic (1.95e-2)" 0.3 0.0 0.1 0.6 0.4 0.2 4.9 0.3 0.9 0.0 44.8 2.2 5.0 0.0 1.2 10.0 0.2 4.5 59.9 2.6 0.0 16.2 0.0 3.7 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 5.3 2.7 1.3 0.0 4.8 145.0 4.7 1.8 0.1 0.0 2.1 1.1 0.3 0.0 0.0 7.5 0.0 1.1 0.4 1.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 25.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 4.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 1395.0 0.1 19.5 1.5 0.0 0.0 0.7 0.0 0.9 0.0 0.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.9 2.6 0.0 1.2 1.1 2.1 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 92.3 0.1 0.0 0.0 11.7 0.0 0.0 44.3 0.0 0.0 3.7 2.1 0.0 0.0 0.0 144.8 0.3 2.5 0.0 0.0 1.3 0.0 0.0 0.9 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 17.5 4.7 0.3 0.0 2486.6 0.0 0.0 15.9 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.6 0.0 0.0 1.4 0.7 0.7 0.0 16.8 0.0 0.5 0.0 0.0 0.2 UBAP1L ENSG00000246922 "Ubiquitin associated protein 1 like" F5GYI3 15 65092760-65115200 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "brain: 14.5;retina: 26.4" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 241.8;Rod photoreceptor cells: 167.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SK-MEL-30: 2.5;U-266/70: 1.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 15.8" HPA065334 Uncertain "Nuclear bodies" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Nuclear bodies" "HPA065334: AB_2685472" "unprognostic (6.89e-3)" "unprognostic (2.62e-1)" "unprognostic (2.66e-3)" "unprognostic (2.73e-2)" "unprognostic (1.64e-1)" "unprognostic (2.98e-3)" "unprognostic (6.59e-2)" "unprognostic (7.02e-2)" "unprognostic (2.78e-1)" "unprognostic (2.56e-1)" "unprognostic (5.62e-5)" "unprognostic (6.40e-3)" "unprognostic (3.11e-6)" "unprognostic (5.03e-2)" "unprognostic (1.39e-1)" "unprognostic (3.70e-1)" "unprognostic (6.11e-3)" 1.2 1.1 8.2 0.3 9.1 0.4 1.3 14.5 13.5 2.9 4.4 1.6 0.2 2.0 0.3 1.1 2.6 0.2 1.0 7.0 10.1 1.2 2.1 1.0 0.4 11.8 7.8 3.4 1.0 0.1 2.1 0.2 10.5 2.0 0.1 26.4 0.8 0.5 2.2 1.2 1.3 0.4 6.1 1.6 0.8 1.7 9.6 0.5 2.1 0.3 0.2 1.6 1.7 11.0 0.0 0.0 0.2 0.7 0.2 0.0 0.6 0.4 0.0 0.2 0.2 0.4 0.1 0.3 0.5 0.0 0.1 0.5 0.4 0.0 0.0 0.6 0.3 0.0 0.4 0.1 0.2 0.3 0.3 0.2 0.3 0.1 0.1 0.5 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.4 0.2 0.0 0.2 0.5 0.1 0.4 0.0 0.1 0.3 0.2 0.2 0.0 2.5 0.3 0.1 0.3 0.0 0.2 0.1 0.2 0.2 1.2 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.2 9.1 14.5 13.5 7.0 10.1 11.8 7.8 10.5 6.1 9.6 11.0 2.1 0.0 1.1 6.2 1.0 0.6 1.7 1.2 2.2 35.3 2.5 1.9 5.0 0.0 1.5 3.7 241.8 0.8 2.4 0.3 1.9 0.5 0.6 1.7 1.9 2.3 1.2 0.4 18.4 0.9 0.3 1.4 1.1 1.7 0.0 3.3 1.8 2.0 0.3 3.3 18.3 1.2 2.0 0.6 0.8 1.3 3.4 1.0 1.8 3.7 0.0 21.8 0.0 5.5 19.9 1.0 1.1 3.4 1.4 1.3 3.1 9.9 0.3 167.3 6.6 1.8 2.2 2.0 3.4 0.8 0.9 0.7 1.9 1.5 0.8 0.6 UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371469-134392108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 265.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 723.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 444.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 444.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (1.64e-3)" "unprognostic (6.30e-3)" "unprognostic (3.42e-2)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" 52.5 74.2 31.5 50.0 33.1 84.4 44.2 36.3 53.2 38.3 30.2 48.0 40.7 53.6 34.8 70.5 37.3 51.0 118.4 34.3 34.8 50.6 56.6 44.9 47.1 29.5 31.0 44.4 53.7 25.8 39.9 48.4 31.0 32.9 42.0 29.2 39.7 23.2 265.8 43.1 46.4 43.3 30.3 43.7 39.6 49.2 32.9 29.3 41.2 99.8 48.1 42.8 43.2 36.7 109.4 27.9 58.2 55.0 50.0 54.1 92.7 80.2 43.5 51.4 60.9 85.6 70.9 58.7 94.1 52.3 138.7 42.7 45.8 60.4 56.0 94.5 47.6 32.1 75.9 92.8 58.2 38.8 63.7 46.5 80.2 47.4 39.3 68.1 44.1 48.8 61.1 103.5 46.8 63.4 62.5 102.1 24.9 32.6 26.7 61.6 63.8 83.8 46.6 82.9 77.6 60.1 62.9 29.3 147.9 62.5 63.0 106.0 87.6 57.8 40.8 78.9 89.4 86.1 129.4 87.0 65.2 72.8 59.4 236.7 58.3 174.0 46.9 68.3 42.9 49.7 58.8 48.1 42.6 47.9 69.9 60.6 444.6 53.0 78.9 48.0 77.5 64.1 31.5 33.1 36.3 53.2 34.3 34.8 29.5 31.0 31.0 30.3 32.9 36.7 187.5 73.7 61.6 40.1 176.5 364.7 321.2 215.1 175.8 77.8 169.9 156.5 315.8 147.3 113.7 75.4 81.3 144.5 182.0 183.1 172.1 173.8 233.2 139.8 102.2 149.7 131.8 261.2 103.0 169.5 123.0 183.3 113.2 167.8 116.8 81.7 115.3 97.4 119.4 87.5 84.2 141.0 181.0 131.5 323.9 315.4 155.0 184.2 227.7 49.6 190.6 150.0 113.3 44.7 68.4 210.6 195.2 113.2 162.5 343.9 153.4 170.7 111.7 91.3 151.2 154.9 262.9 223.5 201.7 145.5 369.7 723.5 192.0 140.4 105.7 488.1 UNC50 "GMH1, UNCL, URP" ENSG00000115446 "Unc-50 inner nuclear membrane RNA binding protein" Q53HI1 2 98608579-98618515 "Predicted membrane proteins" "Protein transport, Transport" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 215.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027009 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA027009: AB_1858620" "prognostic unfavorable (4.79e-4)" "unprognostic (3.28e-2)" "unprognostic (1.23e-1)" "unprognostic (1.74e-2)" "unprognostic (5.54e-2)" "unprognostic (1.86e-2)" "prognostic unfavorable (4.89e-5)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" "unprognostic (5.31e-2)" "unprognostic (6.31e-2)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (2.14e-1)" "unprognostic (4.38e-1)" "unprognostic (7.12e-3)" "unprognostic (4.82e-3)" 36.6 49.1 46.3 34.2 48.2 36.8 45.8 48.8 57.3 38.1 53.6 35.0 37.9 46.3 69.2 30.9 42.7 36.2 38.7 46.2 48.3 52.5 46.9 38.6 41.4 48.5 46.6 44.2 42.0 82.4 41.4 52.2 49.1 41.3 43.2 60.0 56.0 45.4 31.6 39.9 34.4 38.7 49.0 39.3 45.5 48.9 47.2 36.6 64.1 35.9 42.6 37.8 30.5 54.3 55.2 35.6 65.2 44.3 95.7 82.6 73.0 51.2 71.8 61.9 54.2 54.5 64.0 16.6 75.2 44.1 94.0 52.0 45.9 41.5 50.9 56.4 46.2 37.5 47.3 89.4 103.0 71.7 56.7 54.6 92.5 33.1 60.4 71.5 55.1 43.3 61.2 50.2 63.5 39.2 31.7 80.3 49.6 46.1 41.7 20.1 47.3 58.8 68.9 48.6 24.2 35.6 35.9 47.3 86.5 75.8 40.7 91.9 42.7 67.4 41.3 34.5 35.0 76.1 63.2 44.2 63.6 51.7 60.1 61.6 54.3 66.7 50.6 54.9 43.9 52.8 42.2 47.9 54.9 48.1 46.2 52.9 45.3 58.5 51.4 51.3 37.4 44.2 46.3 48.2 48.8 57.3 46.2 48.3 48.5 46.6 49.1 49.0 47.2 54.3 45.3 25.6 31.0 13.7 35.7 47.2 51.2 139.4 42.7 36.7 46.7 40.8 39.5 38.6 85.8 35.0 16.7 118.6 41.2 27.4 33.2 52.3 47.7 38.3 35.3 48.3 21.6 19.1 21.2 53.2 77.1 58.9 19.4 30.7 27.3 23.7 47.2 33.9 73.2 33.7 24.1 34.1 85.5 31.3 33.3 29.9 54.7 33.0 44.4 19.7 41.7 84.6 48.4 19.1 25.8 40.7 33.0 74.9 51.0 75.7 29.0 46.6 73.8 49.8 46.0 45.0 58.9 215.1 58.7 34.6 49.7 152.6 29.2 39.1 30.1 44.6 USF2 "bHLHb12, FIP" ENSG00000105698 "Upstream transcription factor 2, c-fos interacting" Q15853 19 35268962-35279821 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029764, HPA046567" Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm Vesicles "HPA029764: AB_2673190, HPA046567: AB_2679702" "unprognostic (6.10e-3)" "unprognostic (2.27e-1)" "unprognostic (1.06e-2)" "unprognostic (5.03e-3)" "unprognostic (4.60e-2)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "unprognostic (2.87e-1)" "unprognostic (2.10e-1)" "unprognostic (7.07e-2)" "prognostic favorable (5.12e-5)" "unprognostic (7.75e-2)" "unprognostic (8.12e-2)" "unprognostic (7.47e-2)" "unprognostic (5.75e-2)" "unprognostic (6.90e-2)" "prognostic favorable (3.28e-4)" 126.7 132.5 188.9 130.4 191.7 177.7 105.4 190.2 192.9 109.3 147.9 120.8 105.3 104.4 51.5 104.6 104.1 66.3 196.6 181.0 180.3 97.8 185.2 102.2 154.9 192.9 185.4 164.5 121.1 109.4 149.1 63.5 187.2 99.8 54.1 90.4 97.9 57.2 359.3 122.0 112.7 52.4 186.4 160.5 104.1 51.7 191.7 101.3 125.8 195.1 96.7 100.2 99.9 183.2 189.2 190.2 93.6 91.1 161.7 81.5 89.2 101.0 119.7 90.4 69.3 87.3 95.5 183.7 157.6 86.3 96.4 56.5 88.6 79.6 45.4 306.4 135.8 107.5 111.1 143.1 97.8 182.5 177.5 71.7 108.3 58.6 89.1 151.3 62.2 119.6 135.3 260.0 70.5 218.8 200.7 69.8 78.7 171.3 61.1 190.9 123.2 171.2 74.8 119.5 159.3 120.7 188.2 200.4 346.7 80.7 81.8 142.4 107.4 150.0 101.0 99.5 134.4 260.0 286.6 199.7 139.4 114.8 201.0 44.5 8.3 11.1 6.8 11.2 8.2 10.2 7.0 9.0 13.4 13.5 6.3 6.0 7.8 11.7 6.9 50.6 13.8 7.7 188.9 191.7 190.2 192.9 181.0 180.3 192.9 185.4 187.2 186.4 191.7 183.2 58.2 6.4 22.4 29.7 72.5 23.7 23.7 18.7 20.5 66.0 42.2 38.4 71.6 35.8 15.5 31.3 33.3 24.2 108.1 50.7 56.7 33.5 1.1 25.6 31.3 36.5 52.1 37.2 19.7 57.8 38.5 32.7 30.5 34.0 20.3 45.7 38.6 50.5 107.0 94.2 16.9 33.6 20.3 66.8 42.9 3.4 32.0 91.9 26.6 28.1 37.8 118.9 35.0 12.1 19.5 36.0 37.1 31.2 63.8 23.1 58.1 51.7 11.0 53.9 13.1 40.9 35.8 9.0 10.6 34.3 24.7 17.5 56.2 52.0 33.0 35.6 VAT1 "FLJ20230, VATI" ENSG00000108828 "Vesicle amine transport 1" Q99536 17 43014607-43025123 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 133.2;Hofbauer cells: 146.4;Melanocytes: 122.7" "Cancer enhanced" "Detected in all" "melanoma: 295.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 104.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 104.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 680.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045170 Uncertain NA NA 2700000 "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA045170: AB_10964166" "unprognostic (2.22e-2)" "unprognostic (4.41e-3)" "unprognostic (6.86e-3)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (9.67e-2)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.16e-2)" "unprognostic (5.56e-2)" "unprognostic (1.86e-2)" "unprognostic (1.17e-3)" "unprognostic (2.38e-1)" "prognostic favorable (5.89e-4)" "unprognostic (1.71e-2)" "unprognostic (3.66e-2)" "unprognostic (1.07e-1)" "unprognostic (3.36e-2)" 180.4 251.5 53.6 32.1 57.6 86.5 137.5 55.3 67.3 160.8 54.8 97.5 25.7 121.4 65.0 132.6 78.4 85.6 74.7 47.3 129.9 70.5 44.5 111.7 29.0 88.4 132.3 184.8 67.2 54.7 103.7 83.9 173.9 64.9 32.9 7.6 86.3 52.2 29.2 194.3 65.1 94.2 60.5 40.3 56.1 79.2 93.3 63.7 68.3 45.8 33.7 109.5 126.3 77.3 38.9 225.0 53.6 119.0 556.9 435.5 75.5 94.2 282.1 89.7 167.1 139.7 83.2 7.7 128.8 395.8 283.7 58.9 94.1 81.6 82.7 14.4 127.6 36.2 107.3 279.5 357.7 177.6 271.5 234.3 119.2 154.0 71.2 203.8 428.9 230.5 77.3 12.1 227.3 37.2 262.2 76.6 68.1 111.6 106.2 37.3 66.1 19.4 102.2 76.6 50.0 94.6 51.3 29.5 680.8 217.9 82.5 99.4 431.7 199.9 92.5 226.2 22.9 19.4 30.2 14.3 203.1 132.0 31.4 104.0 16.6 24.9 13.1 7.9 15.3 19.9 18.5 13.6 8.4 19.5 16.8 10.4 5.1 11.1 9.2 4.1 13.4 19.0 53.6 57.6 55.3 67.3 47.3 129.9 88.4 132.3 173.9 60.5 93.3 77.3 133.2 22.4 13.9 1.0 17.2 28.4 14.2 17.9 34.1 1.1 29.5 30.2 31.6 17.2 10.7 23.9 4.2 6.5 6.5 9.2 17.6 99.7 27.5 14.2 32.5 71.0 15.1 12.6 2.3 43.4 45.1 91.4 8.2 32.6 77.2 93.8 73.9 15.8 146.4 5.0 2.4 4.1 4.1 40.0 32.4 45.2 51.9 43.9 122.7 6.5 16.1 4.2 3.1 3.5 4.1 49.6 10.4 58.6 19.6 25.5 36.5 60.1 12.6 1.8 13.1 19.4 39.1 12.8 15.5 35.1 33.5 11.1 12.6 31.2 4.7 21.8 VEGFB "VEGFL, VRF" ENSG00000173511 "Vascular endothelial growth factor B" P49765 11 64234584-64239264 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.9;Muller glia cells: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 30.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 30.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 186000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.33e-2)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (2.45e-1)" "unprognostic (4.68e-1)" "unprognostic (5.01e-3)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (1.67e-2)" "unprognostic (8.08e-3)" "unprognostic (2.00e-1)" "unprognostic (4.15e-2)" "unprognostic (4.31e-3)" 209.8 82.0 45.7 12.0 51.3 3.9 151.3 41.8 53.1 103.6 48.2 151.5 12.1 99.9 7.2 50.8 72.5 19.2 253.3 38.7 45.1 84.6 44.0 82.5 14.4 54.8 47.4 82.6 84.9 18.3 104.2 9.8 45.0 92.7 4.7 12.7 57.7 28.5 143.8 77.3 59.5 10.2 44.2 55.9 89.2 17.5 50.6 6.6 83.7 51.5 9.1 118.0 77.5 37.3 15.4 25.9 9.9 28.1 49.7 36.8 12.7 14.7 27.8 13.1 16.0 13.8 31.7 19.8 28.6 14.0 28.8 20.8 15.8 11.5 2.3 20.6 15.1 16.7 33.9 13.3 45.4 4.8 20.1 39.6 12.0 19.6 12.2 33.9 18.4 20.6 20.2 32.5 22.2 31.8 27.4 12.6 7.0 10.9 22.3 32.1 20.5 46.5 11.0 19.5 14.0 46.4 12.4 38.1 57.4 7.6 25.1 5.6 13.0 50.8 30.2 23.1 8.7 90.5 45.5 15.4 41.6 5.3 25.1 0.3 0.2 0.6 0.9 0.0 0.8 3.0 0.8 0.9 0.4 2.4 0.9 1.6 0.0 0.4 0.0 30.5 0.5 0.4 45.7 51.3 41.8 53.1 38.7 45.1 54.8 47.4 45.0 44.2 50.6 37.3 54.1 19.2 32.6 43.8 27.6 12.7 6.7 10.1 2.2 47.9 32.8 65.7 204.9 10.0 7.6 14.7 33.3 9.6 68.3 11.9 39.2 14.8 1.1 24.2 47.7 21.9 53.3 4.4 7.3 12.9 16.8 68.6 5.1 31.6 18.4 62.7 19.6 9.8 51.4 65.6 26.6 12.2 20.3 31.5 21.5 3.5 60.9 50.0 35.6 19.7 17.7 130.6 12.3 29.1 11.8 14.5 7.3 109.1 12.3 11.5 20.3 31.6 8.9 39.6 6.6 47.4 53.7 0.5 1.2 6.4 13.9 8.9 19.0 34.3 12.8 7.5 VGF "SCG7, SgVII" ENSG00000128564 "VGF nerve growth factor inducible" O15240 7 101162509-101165569 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 1407.4" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 128.3;Horizontal cells: 225.4" "Cancer enriched" "Detected in many" 6 "melanoma: 236.3" "Region enriched" "Detected in all" 6 "hypothalamus: 1407.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 172.0;SK-MEL-30: 511.5;U-2 OS: 85.9;WM-115: 141.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055177, HPA072505" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1270000 3100000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus, Vesicles" "HPA055177: AB_2682728, HPA072505: AB_2686528" "unprognostic (3.04e-2)" "unprognostic (3.45e-1)" "unprognostic (3.19e-3)" "prognostic unfavorable (4.25e-4)" "prognostic unfavorable (3.31e-4)" "unprognostic (1.51e-2)" "unprognostic (2.86e-2)" "unprognostic (1.66e-3)" "unprognostic (2.25e-2)" "unprognostic (8.77e-2)" "unprognostic (3.84e-3)" "unprognostic (3.70e-3)" "unprognostic (9.82e-3)" "unprognostic (3.79e-1)" "unprognostic (7.23e-2)" "unprognostic (4.36e-3)" "unprognostic (2.21e-1)" 2.1 3.1 23.7 0.8 24.8 0.1 0.1 5.5 174.6 0.0 0.0 0.5 0.1 0.7 0.0 0.0 0.0 0.0 0.1 22.7 1407.4 3.6 0.0 0.1 0.0 235.4 69.9 0.1 16.1 0.0 117.0 0.0 158.8 0.1 0.0 2.2 0.0 0.0 0.0 0.8 0.3 0.2 16.6 0.1 1.9 0.9 48.7 0.0 0.6 0.0 0.0 0.0 0.1 27.3 2.2 1.1 1.1 9.5 0.0 0.0 10.3 0.9 0.0 0.0 0.0 2.4 0.9 0.1 3.1 0.0 1.4 1.4 0.5 0.1 0.0 1.0 0.7 0.3 0.0 0.9 0.1 0.6 4.4 0.1 0.2 0.2 0.7 0.0 0.0 0.1 3.7 2.3 0.0 23.4 0.1 2.4 17.6 1.0 2.3 0.8 0.0 0.1 0.3 0.1 14.1 172.0 0.3 0.9 511.5 1.1 0.4 0.3 0.0 0.4 85.9 0.0 2.0 0.1 0.8 4.7 13.5 0.4 141.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 24.8 5.5 174.6 22.7 1407.4 235.4 69.9 158.8 16.6 48.7 27.3 1.7 0.0 0.0 3.6 0.9 1.5 1.0 0.0 1.2 22.0 0.9 0.6 2.9 0.0 0.0 0.0 0.0 1.5 1.0 1.3 29.4 0.3 0.1 0.4 0.4 0.9 128.3 0.0 22.7 0.0 8.4 0.3 3.1 0.5 0.0 1.4 0.0 0.0 0.6 225.4 37.7 4.5 0.0 0.0 0.4 0.6 0.6 0.7 0.0 11.2 0.0 2.1 0.0 4.0 4.8 5.9 2.8 0.0 0.9 4.3 2.7 1.2 0.0 5.0 0.0 0.1 0.8 0.2 4.3 0.6 2.3 1.4 0.5 5.4 2.3 0.6 VPS26C "DCRA, DSCR3" ENSG00000157538 "VPS26 endosomal protein sorting factor C" O14972 21 37223420-37267919 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 26.4;Exocrine glandular cells: 28.0;Extravillous trophoblasts: 26.4;Hofbauer cells: 32.7;Pancreatic endocrine cells: 33.2;Proximal tubular cells: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023288 Uncertain Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA023288: AB_1847872" "unprognostic (1.01e-3)" "unprognostic (6.42e-2)" "unprognostic (7.96e-3)" "unprognostic (2.15e-2)" "unprognostic (4.10e-3)" "unprognostic (2.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.40e-1)" "unprognostic (3.15e-1)" "unprognostic (7.76e-2)" "unprognostic (5.40e-2)" "unprognostic (1.97e-1)" "prognostic favorable (8.54e-4)" "unprognostic (1.72e-1)" "unprognostic (3.24e-1)" "unprognostic (5.24e-2)" "unprognostic (3.16e-1)" 19.8 24.5 14.8 18.5 16.1 21.4 15.8 16.8 15.8 16.3 15.9 26.6 28.0 14.8 11.4 21.2 13.8 19.6 24.9 14.4 15.6 32.9 29.5 22.1 22.6 16.1 15.9 17.4 22.6 17.7 8.6 21.4 16.6 14.3 26.0 13.6 16.9 15.8 31.5 15.7 26.9 19.9 16.2 20.2 21.2 7.5 16.5 28.1 18.1 37.8 23.6 21.9 14.2 17.6 31.8 13.8 30.2 26.5 55.4 49.4 34.3 29.9 66.2 26.6 40.2 19.2 32.7 22.0 11.7 70.0 63.9 15.0 32.6 32.1 26.1 52.8 23.5 37.6 13.6 18.7 49.1 27.8 24.3 43.5 31.2 31.0 50.4 48.1 51.4 40.5 24.0 46.8 52.5 14.1 47.2 23.7 34.4 48.7 13.8 44.8 14.5 32.5 32.8 23.7 24.4 32.6 20.6 40.9 65.5 39.0 38.4 22.0 41.0 30.6 10.8 33.2 18.5 71.3 78.0 30.3 48.3 47.9 35.2 58.6 48.6 84.9 50.7 60.5 46.8 37.5 43.1 45.4 47.7 29.4 39.8 41.0 50.1 52.9 55.7 19.4 54.9 54.1 14.8 16.1 16.8 15.8 14.4 15.6 16.1 15.9 16.6 16.2 16.5 17.6 18.1 9.6 21.9 0.0 4.3 0.0 0.0 0.0 0.0 0.0 14.5 13.3 0.0 0.0 6.8 9.2 0.0 16.0 23.8 0.0 21.5 26.4 0.0 12.5 12.7 8.4 0.0 0.0 0.0 28.0 26.4 5.4 0.0 16.1 8.8 19.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 16.5 0.0 0.0 0.0 0.0 33.2 0.0 0.0 3.1 0.0 0.0 29.7 4.4 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 14.6 8.5 10.1 0.0 0.0 VSTM2B ENSG00000187135 "V-set and transmembrane domain containing 2B" A6NLU5 19 29526499-29564479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 46.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 31.6;Excitatory neurons: 55.9;Inhibitory neurons: 37.8;Oligodendrocyte precursor cells: 97.5;Oligodendrocytes: 228.2" "Cancer enhanced" "Detected in some" "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SK-MEL-30: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.74e-1)" "unprognostic (1.87e-3)" "unprognostic (6.64e-2)" "unprognostic (1.08e-2)" "unprognostic (5.35e-2)" 0.0 0.1 32.2 0.0 41.0 0.0 0.0 14.7 46.8 2.9 0.2 0.4 0.0 0.1 0.4 0.0 0.1 0.0 0.0 35.6 23.1 0.0 0.0 0.0 0.0 26.4 20.6 0.0 0.0 0.0 0.2 0.0 24.1 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.2 17.2 0.0 0.0 0.0 27.5 0.0 0.0 0.0 0.0 0.0 1.7 40.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 32.2 41.0 14.7 46.8 35.6 23.1 26.4 20.6 24.1 17.2 27.5 40.9 0.0 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 55.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 37.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 2.1 0.0 97.5 228.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WARS1 "IFI53, IFP53, WARS" ENSG00000140105 "Tryptophanyl-tRNA synthetase 1" P23381 14 100333790-100376805 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 324.4" "Cell type enhanced" "Detected in some" "Adipocytes: 66.4;Cytotrophoblasts: 16.5;Endothelial cells: 38.5;Hofbauer cells: 43.1;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 1345.3;non-classical monocyte: 1608.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 908.5;SK-MEL-30: 1012.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005573, HPA018944" Enhanced Enhanced Cytosol No No 49000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA005573: AB_2667366, HPA018944: AB_2669986" "unprognostic (5.36e-2)" "unprognostic (5.98e-2)" "unprognostic (3.99e-2)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.14e-2)" "unprognostic (4.26e-2)" "prognostic favorable (1.94e-4)" "unprognostic (4.84e-2)" "unprognostic (3.21e-1)" "unprognostic (3.53e-3)" "unprognostic (1.37e-1)" "unprognostic (9.45e-2)" "unprognostic (1.62e-1)" "unprognostic (5.92e-3)" 100.7 67.9 40.3 185.6 44.4 70.5 65.4 40.1 45.5 35.9 45.2 67.8 44.8 39.6 70.3 54.4 50.8 48.7 157.6 44.2 56.0 83.6 47.9 207.5 139.0 72.0 52.6 21.2 47.5 39.2 63.4 324.4 65.3 49.1 72.0 37.8 49.5 38.3 74.7 28.4 67.7 76.2 47.6 110.6 70.1 67.7 55.0 61.7 159.9 67.0 86.2 107.7 30.7 44.9 91.2 85.7 54.6 319.1 78.7 110.7 87.3 117.4 220.7 232.1 301.4 57.4 80.2 101.7 105.5 277.4 59.7 151.1 158.8 130.3 153.1 154.4 48.3 64.1 60.9 72.3 908.5 184.9 101.6 126.9 186.9 141.3 290.1 74.5 225.0 66.1 202.8 255.0 107.5 178.0 64.3 87.1 55.4 94.1 152.2 51.4 86.5 64.9 119.3 80.8 145.7 84.9 69.4 58.7 1012.4 70.5 153.6 234.7 153.1 25.7 58.9 269.2 61.3 446.4 277.1 191.9 295.0 144.2 205.5 96.5 471.7 610.4 41.5 1345.3 38.4 71.4 34.5 38.4 337.9 68.0 24.8 28.6 170.9 44.5 1608.2 54.7 44.8 672.7 40.3 44.4 40.1 45.5 44.2 56.0 72.0 52.6 65.3 47.6 55.0 44.9 66.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 16.5 3.7 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 11.5 5.5 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 16.6 0.5 0.0 0.0 0.0 WDFY1 "FENS-1, KIAA1435, WDF1, ZFYVE17" ENSG00000085449 "WD repeat and FYVE domain containing 1" Q8IWB7 2 223855716-223945357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050603, HPA079597" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Vesicles" "HPA050603: AB_2681188, HPA079597: " "unprognostic (2.49e-1)" "unprognostic (1.24e-1)" "unprognostic (2.94e-1)" "unprognostic (7.62e-2)" "unprognostic (8.24e-2)" "unprognostic (5.31e-2)" "unprognostic (2.63e-2)" "unprognostic (7.10e-2)" "unprognostic (1.26e-1)" "unprognostic (2.29e-2)" "unprognostic (1.23e-3)" "unprognostic (1.36e-1)" "unprognostic (3.81e-3)" "unprognostic (3.94e-1)" "unprognostic (2.98e-1)" "unprognostic (3.04e-1)" "unprognostic (7.55e-2)" 18.6 13.2 9.3 18.0 9.5 48.5 14.4 9.3 12.0 20.5 11.2 20.4 15.6 22.6 19.8 14.4 20.5 17.5 11.7 9.2 10.7 14.8 18.0 18.4 23.3 11.0 10.2 20.2 14.1 19.8 8.7 27.4 11.4 16.2 20.1 15.9 13.5 12.8 11.4 13.5 15.9 19.6 9.7 21.2 19.8 10.9 10.5 15.9 22.1 12.6 18.9 17.9 13.7 11.1 27.9 19.3 34.9 27.2 46.4 44.0 43.7 34.7 48.3 37.5 30.4 81.4 25.0 7.7 30.8 60.6 47.3 19.2 18.7 52.3 40.4 15.6 15.8 19.2 31.9 59.2 36.4 15.2 15.8 39.0 37.9 46.3 71.0 62.4 63.9 16.2 34.3 23.4 44.4 26.8 6.5 11.1 34.5 20.7 16.6 25.3 44.8 8.6 28.4 47.7 29.6 15.7 20.7 19.2 90.9 41.6 12.5 38.1 70.9 74.9 25.7 13.5 18.0 28.8 4.6 21.4 36.3 32.9 26.2 4.4 21.5 8.1 13.7 29.0 16.6 14.1 9.7 13.5 14.8 11.7 10.0 9.5 10.3 24.0 25.7 3.0 9.7 17.6 9.3 9.5 9.3 12.0 9.2 10.7 11.0 10.2 11.4 9.7 10.5 11.1 40.0 16.0 9.3 22.5 22.0 12.5 14.5 19.9 17.1 14.0 11.8 7.6 7.7 12.8 24.4 16.5 8.4 22.6 25.5 36.4 9.8 12.9 0.8 23.2 30.7 34.1 10.3 11.2 28.7 17.2 11.2 21.4 29.6 36.5 17.7 12.5 16.8 25.7 17.9 28.6 28.1 15.2 8.2 26.3 17.2 2.4 14.6 24.4 35.6 27.2 25.6 13.9 24.7 33.7 39.8 18.0 24.4 23.7 21.8 16.6 16.0 14.4 29.9 10.9 6.6 13.1 26.7 3.8 8.8 24.4 15.5 19.0 21.1 15.0 21.8 28.7 WDR45 "JM5, NBIA5, WDRX1, WIPI4" ENSG00000196998 "WD repeat domain 45" Q9Y484 X 49074433-49101170 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027562 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA027562: AB_10610565" "unprognostic (1.39e-1)" "prognostic favorable (1.21e-4)" "unprognostic (1.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.32e-1)" "prognostic favorable (1.61e-4)" "unprognostic (4.30e-2)" "unprognostic (6.66e-3)" "unprognostic (7.12e-2)" "unprognostic (3.57e-1)" "unprognostic (3.22e-2)" "unprognostic (1.77e-1)" "unprognostic (5.06e-3)" "unprognostic (2.85e-1)" "unprognostic (5.27e-1)" "unprognostic (3.60e-2)" "unprognostic (1.11e-3)" 58.0 74.7 53.3 22.4 59.1 43.2 54.3 56.1 57.8 54.8 59.4 52.3 27.6 51.5 208.4 38.5 45.7 29.7 79.6 53.6 55.3 61.8 68.5 46.6 25.7 63.8 61.1 49.0 58.6 54.8 43.4 21.9 58.1 48.9 19.6 21.2 50.8 34.4 115.9 48.5 38.2 24.7 57.8 45.0 59.0 10.0 61.0 32.3 52.9 87.5 23.2 45.9 43.0 52.7 36.3 41.9 23.4 23.7 50.1 63.7 45.7 39.0 80.6 30.1 42.1 22.1 51.5 25.1 21.6 77.1 38.6 30.8 35.3 31.6 21.6 27.6 61.0 15.6 79.5 33.5 114.2 12.1 34.5 57.2 54.9 49.4 52.1 47.8 30.7 23.8 33.3 42.8 40.3 40.9 25.6 31.0 23.8 15.9 36.3 20.4 34.8 85.7 53.2 32.8 31.3 46.8 49.2 37.5 120.5 29.9 23.9 43.4 41.8 32.8 29.4 65.6 16.6 66.2 48.9 18.1 60.1 19.5 24.1 125.4 89.0 82.0 54.5 81.6 54.3 49.1 41.0 51.4 67.1 48.4 32.0 36.5 88.9 83.7 97.9 68.0 65.3 72.0 53.3 59.1 56.1 57.8 53.6 55.3 63.8 61.1 58.1 57.8 61.0 52.7 36.5 32.1 34.6 15.0 34.0 46.5 54.2 49.3 36.5 18.8 43.7 41.8 35.8 35.8 42.6 35.0 12.5 30.6 56.5 37.9 56.7 71.3 1.3 22.5 35.0 30.5 28.8 71.8 8.9 98.5 56.8 50.8 43.3 26.1 27.3 27.5 35.0 49.7 42.1 26.9 9.3 32.2 10.2 38.8 44.1 3.8 40.4 47.1 35.6 6.5 74.8 38.7 68.0 4.5 11.0 109.6 44.0 32.4 86.5 67.9 68.5 131.2 23.4 24.0 19.7 42.4 44.5 2.6 5.0 24.8 47.3 62.1 33.4 48.3 28.7 73.4 WDR61 REC14 ENSG00000140395 "WD repeat domain 61" Q9GZS3 15 78277835-78299703 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039932, HPA040065" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 28000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA039932: AB_10796336, HPA040065: AB_10793926" "unprognostic (1.08e-1)" "unprognostic (1.85e-2)" "unprognostic (8.91e-2)" "unprognostic (1.07e-1)" "unprognostic (2.09e-1)" "unprognostic (3.36e-1)" "unprognostic (2.44e-1)" "unprognostic (1.60e-1)" "unprognostic (3.05e-1)" "unprognostic (2.74e-3)" "unprognostic (4.21e-1)" "unprognostic (5.72e-2)" "prognostic favorable (2.03e-10)" "unprognostic (1.04e-1)" "unprognostic (3.13e-1)" "unprognostic (3.18e-1)" "unprognostic (1.09e-2)" 38.8 52.7 34.5 29.6 36.5 61.5 59.9 50.4 63.0 40.8 31.1 39.5 36.2 34.9 115.7 40.1 46.6 28.6 41.0 40.8 40.4 60.8 50.9 34.6 37.4 41.5 41.2 34.6 41.3 55.6 49.9 35.5 40.0 46.0 43.5 49.4 39.5 37.4 45.4 52.1 30.4 41.4 38.2 29.9 33.5 49.0 37.0 48.5 56.8 38.2 46.0 41.4 32.4 61.5 39.3 92.4 74.3 77.4 74.1 61.6 56.1 60.9 68.6 76.6 73.6 87.9 67.9 80.7 72.6 69.8 119.2 78.2 165.8 71.5 58.3 53.9 123.8 66.2 79.9 84.6 62.6 99.2 63.3 52.8 50.5 30.8 24.0 52.7 82.7 80.0 113.1 78.8 92.5 116.6 82.3 81.6 54.3 98.5 76.2 74.7 59.7 89.1 81.3 112.3 103.7 56.2 88.0 90.9 323.7 76.9 56.0 124.2 58.2 53.7 66.0 38.2 103.6 69.3 113.7 113.0 80.5 153.3 112.6 39.0 91.2 33.6 59.6 100.0 65.0 66.4 59.7 62.1 134.2 53.5 62.2 68.6 7.7 72.4 86.0 71.6 72.7 89.1 34.5 36.5 50.4 63.0 40.8 40.4 41.5 41.2 40.0 38.2 37.0 61.5 38.7 35.3 44.7 20.5 26.7 49.1 61.5 105.0 31.9 57.2 44.8 47.2 25.8 28.6 57.5 38.6 47.9 106.1 29.2 23.2 125.2 62.5 32.2 41.5 38.6 42.2 23.4 37.6 34.6 55.6 78.1 51.0 20.4 29.1 47.5 49.1 40.0 47.0 66.1 43.7 36.8 38.0 93.6 37.0 47.2 12.4 50.1 37.0 58.7 12.2 61.1 81.9 42.2 17.1 33.1 41.0 28.5 50.8 36.4 51.6 35.4 132.7 70.1 50.7 6.6 37.8 90.2 122.4 60.2 38.3 58.7 92.4 31.7 59.4 52.4 57.7 WDR93 "C1d-87, CFAP297, FAP297" ENSG00000140527 "WD repeat domain 93" Q6P2C0 15 89690811-89743638 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 8.9;testis: 11.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 20.9;Early spermatids: 49.1;Endometrial ciliated cells: 28.1;Late spermatids: 42.4;Respiratory ciliated cells: 47.7;Spermatocytes: 30.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA046196, HPA048112" Uncertain Uncertain "Actin filaments" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "HPA046196: AB_2679582, HPA048112: AB_2680267" "unprognostic (2.56e-3)" "unprognostic (3.21e-3)" "unprognostic (7.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.90e-2)" "unprognostic (3.01e-1)" "unprognostic (1.15e-2)" "unprognostic (2.08e-2)" "unprognostic (1.22e-2)" "unprognostic (7.40e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (2.40e-2)" "unprognostic (4.73e-2)" "unprognostic (9.84e-2)" "unprognostic (4.44e-2)" 0.4 0.2 0.6 0.0 0.6 0.4 0.7 1.6 0.6 0.6 3.5 0.1 0.0 0.4 4.9 0.0 8.9 0.2 1.2 0.8 1.0 1.0 0.1 1.0 0.2 2.4 2.9 0.4 0.6 0.5 0.8 0.1 1.1 0.6 0.1 2.8 0.3 0.5 0.3 0.2 0.1 0.0 1.6 0.1 0.1 11.6 0.9 0.1 1.8 0.0 0.1 0.0 0.0 1.0 0.3 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.3 0.0 0.3 0.3 0.0 0.4 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.5 0.2 0.7 0.2 1.0 0.1 0.1 0.4 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.6 0.6 1.6 0.6 0.8 1.0 2.4 2.9 1.1 1.6 0.9 1.0 0.1 3.2 0.5 2.9 0.0 0.3 0.7 1.8 0.0 2.7 0.8 0.6 0.5 0.0 4.2 9.2 20.9 0.4 0.1 0.1 3.9 0.8 49.1 28.1 0.6 0.7 0.0 0.0 2.7 0.2 0.3 0.4 0.0 0.8 0.0 0.4 0.4 0.0 0.2 3.3 2.1 0.1 0.0 0.3 0.8 42.4 1.5 0.3 1.8 0.0 0.6 0.6 0.0 0.5 1.0 0.3 1.1 0.7 0.1 0.7 0.0 2.1 47.7 14.8 0.0 0.9 0.6 30.4 5.7 0.0 0.1 0.3 0.6 2.9 0.2 0.4 WIPI1 "ATG18, ATG18A, FLJ10055, WIPI49" ENSG00000070540 "WD repeat domain, phosphoinositide interacting 1" Q5MNZ9 17 68420948-68457513 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 127.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 165.7;Syncytiotrophoblasts: 125.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 114.1;eosinophil: 223.6" "Lineage enriched" "Detected in all" 9 "granulocytes: 223.6" "Cell line enhanced" "Detected in many" "ASC diff: 224.3;HHSteC: 216.7;HSkMC: 180.8;SK-MEL-30: 183.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007493, CAB037230" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB037230: AB_1841265, HPA007493: AB_1848642" "unprognostic (2.83e-2)" "unprognostic (7.85e-2)" "unprognostic (1.05e-3)" "unprognostic (1.31e-1)" "unprognostic (1.42e-1)" "unprognostic (3.03e-2)" "unprognostic (3.97e-3)" "unprognostic (1.78e-2)" "prognostic favorable (3.11e-4)" "unprognostic (2.86e-1)" "unprognostic (1.79e-1)" "unprognostic (3.06e-1)" "unprognostic (6.32e-3)" "unprognostic (6.56e-2)" "unprognostic (4.99e-2)" "unprognostic (1.78e-1)" "unprognostic (1.89e-3)" 31.3 18.8 11.2 14.1 11.2 26.6 30.5 12.5 15.1 33.1 19.1 36.4 12.8 15.3 14.4 14.8 12.6 23.3 78.4 10.6 12.9 33.3 18.7 26.2 8.7 12.5 12.0 11.2 29.8 25.2 17.8 62.4 12.5 17.4 38.5 8.2 55.0 18.3 127.2 21.9 14.8 18.8 11.4 12.5 29.3 9.6 15.5 5.9 21.1 97.5 16.7 22.0 14.4 11.9 4.9 9.8 8.6 12.5 224.3 167.2 49.0 36.3 163.5 13.7 43.6 7.2 7.3 3.0 16.0 74.2 47.9 3.7 3.3 22.1 23.9 4.4 4.6 34.7 3.2 42.6 216.7 2.4 48.5 180.8 39.5 54.2 72.0 44.2 61.3 5.3 2.5 82.0 41.1 29.9 0.5 7.1 1.8 12.7 15.0 0.4 30.3 35.7 20.2 16.7 2.4 11.4 7.7 103.8 183.4 44.4 54.8 9.5 61.2 65.4 10.1 31.0 8.6 78.2 92.0 10.5 98.9 16.5 29.7 114.1 18.4 223.6 11.9 22.7 5.3 4.4 3.1 11.7 9.0 1.4 0.2 5.6 39.0 10.7 24.7 6.3 2.7 15.0 11.2 11.2 12.5 15.1 10.6 12.9 12.5 12.0 12.5 11.4 15.5 11.9 26.2 9.6 11.5 12.7 13.3 7.8 11.9 45.6 0.6 15.0 24.1 8.9 7.3 28.6 48.5 16.5 2.1 44.0 18.3 30.2 31.3 31.2 6.3 26.3 19.9 17.2 12.0 56.6 9.4 57.2 165.7 41.2 25.5 40.0 7.0 12.3 33.9 11.7 35.6 10.1 8.2 67.6 44.7 18.2 14.5 5.2 46.3 37.1 42.7 20.6 34.2 10.6 20.6 6.0 12.2 28.8 20.1 42.2 83.3 55.3 8.5 71.8 49.6 15.7 26.3 10.1 24.1 5.0 5.1 3.3 6.8 125.1 13.6 27.8 28.2 36.7 YIPF1 "DJ167A19.1, FinGER1" ENSG00000058799 "Yip1 domain family member 1" Q9Y548 1 53851719-53889798 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.0;Syncytiotrophoblasts: 129.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014716, HPA073931" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA014716: AB_1847686, HPA073931: " "unprognostic (4.94e-2)" "unprognostic (4.50e-1)" "unprognostic (6.37e-2)" "unprognostic (2.06e-2)" "unprognostic (3.93e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.96e-1)" "unprognostic (6.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.38e-1)" "unprognostic (5.39e-3)" "unprognostic (6.35e-1)" 7.1 9.2 5.3 6.2 5.6 5.7 8.5 5.8 15.2 6.7 6.9 7.9 6.9 4.1 7.6 9.0 6.3 5.5 6.6 5.9 6.3 11.1 13.5 7.7 7.1 6.7 5.8 7.0 6.8 7.0 6.2 9.7 6.8 11.3 9.2 7.2 11.7 4.8 14.6 9.4 6.9 6.0 6.2 8.2 8.7 7.2 6.0 8.8 22.1 10.4 10.7 7.7 7.1 6.4 11.0 6.4 10.1 7.1 11.9 13.1 9.0 7.7 12.0 14.0 18.3 7.1 3.3 3.8 12.9 9.2 21.6 13.2 12.9 17.0 14.4 27.4 10.3 8.9 6.4 11.6 15.9 10.0 8.1 13.3 15.8 11.3 13.5 12.0 15.0 13.2 9.6 10.0 14.0 9.2 10.8 14.2 7.7 12.7 10.4 6.6 9.3 15.4 11.5 5.8 4.5 5.6 7.4 13.8 35.4 31.0 21.4 11.1 7.1 5.7 5.8 10.4 6.8 20.1 24.7 7.0 9.3 8.1 5.0 19.1 18.4 20.2 11.8 16.5 11.0 10.4 10.0 12.1 16.6 13.8 9.5 9.2 38.3 11.0 23.3 11.5 24.3 16.5 5.3 5.6 5.8 15.2 5.9 6.3 6.7 5.8 6.8 6.2 6.0 6.4 11.6 6.4 12.6 9.8 9.0 8.5 17.6 19.2 9.6 6.6 20.0 12.4 9.6 24.3 24.0 9.2 0.0 80.0 8.5 14.6 11.7 28.3 30.5 11.4 10.9 10.9 9.6 12.2 9.8 32.6 28.4 9.9 9.7 14.7 9.5 6.3 11.7 20.8 39.7 10.1 8.2 27.5 30.5 19.4 7.7 54.9 5.9 18.9 10.6 11.2 20.2 16.5 21.6 8.5 11.5 32.5 10.8 9.4 28.1 33.2 12.3 17.7 19.7 6.5 0.0 5.6 17.7 22.2 20.9 12.3 10.9 129.6 10.8 17.7 10.8 29.0 YPEL4 FLJ30213 ENSG00000166793 "Yippee like 4" Q96NS1 11 57645087-57649944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.0;Early spermatids: 29.7;Erythroid cells: 92.4;Langerhans cells: 15.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.2;ASC diff: 2.1;SK-MEL-30: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045621 Uncertain NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "HPA045621: " "unprognostic (6.91e-3)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (8.62e-3)" "unprognostic (2.40e-1)" "unprognostic (7.50e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" "unprognostic (4.28e-2)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (4.18e-1)" "unprognostic (1.34e-6)" "unprognostic (1.50e-4)" "unprognostic (9.56e-2)" "unprognostic (1.86e-3)" "unprognostic (2.92e-1)" 1.6 3.3 9.6 0.3 12.8 7.2 1.9 11.7 23.2 4.8 0.0 1.9 0.4 3.6 0.2 0.6 1.9 1.2 0.8 12.3 10.5 0.7 0.4 1.6 0.2 11.3 6.9 5.4 0.4 0.1 5.4 0.7 11.0 0.8 0.2 3.2 0.7 0.4 0.4 0.9 1.1 1.3 4.3 1.2 0.8 2.4 7.7 0.3 0.8 0.7 0.1 0.8 2.8 16.5 0.2 0.1 3.2 0.2 2.1 1.9 0.4 0.1 1.7 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.8 0.9 0.1 0.3 0.0 1.8 0.0 0.7 0.0 0.2 0.1 0.0 0.7 0.3 1.2 0.0 0.1 1.3 0.3 0.2 0.0 0.0 0.0 0.8 0.1 0.1 4.4 1.8 0.3 0.0 0.0 0.1 0.7 0.0 0.0 1.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.6 12.8 11.7 23.2 12.3 10.5 11.3 6.9 11.0 4.3 7.7 16.5 0.7 0.0 0.0 1.0 0.9 1.1 0.8 0.1 0.6 34.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.6 29.7 0.6 1.7 1.2 0.0 92.4 13.4 0.0 0.6 4.3 0.5 0.6 3.8 0.1 0.4 0.1 1.0 8.4 15.0 0.0 0.0 1.3 15.7 12.8 1.2 3.3 5.4 1.0 0.1 1.0 0.0 5.5 12.3 0.1 0.0 0.4 0.4 0.2 0.0 0.0 0.0 2.8 0.0 4.4 2.6 0.3 0.1 0.4 1.3 3.3 2.5 0.1 0.0 0.1 ZC3H13 "DKFZp434D1812, KIAA0853, Xio" ENSG00000123200 "Zinc finger CCCH-type containing 13" Q5T200 13 45954465-46052759 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 166.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039340, HPA040140, HPA047806" Uncertain Approved "Nuclear membrane,Actin filaments" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear membrane, Actin filaments" "HPA039340: AB_2676454, HPA040140: AB_2676858, HPA047806: AB_2680161" "unprognostic (1.50e-1)" "unprognostic (6.28e-3)" "unprognostic (1.25e-1)" "unprognostic (2.22e-2)" "unprognostic (7.53e-2)" "unprognostic (1.24e-1)" "unprognostic (2.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.77e-1)" "unprognostic (1.71e-1)" "unprognostic (2.01e-1)" "unprognostic (1.38e-1)" "prognostic favorable (2.69e-4)" "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (3.45e-1)" "unprognostic (9.21e-3)" 15.4 10.1 21.9 13.4 26.9 15.0 15.9 16.9 22.0 14.8 6.7 15.0 9.3 18.5 15.3 10.7 12.0 11.4 11.7 17.4 24.9 12.7 58.6 12.6 15.9 18.4 24.2 17.7 9.4 17.7 9.1 15.5 20.4 15.6 12.3 15.7 12.5 14.3 16.0 13.8 11.7 14.6 17.9 16.4 12.0 11.4 25.2 22.5 17.5 15.8 13.1 12.9 11.0 27.3 16.6 20.9 51.1 19.9 36.0 36.6 21.4 29.9 24.5 24.1 15.9 32.3 28.9 46.4 18.8 31.9 16.6 29.0 32.1 25.0 38.4 41.4 32.5 53.3 21.0 28.2 21.2 68.5 28.3 28.2 20.4 25.5 30.0 22.9 26.6 26.5 29.1 13.8 25.6 21.6 34.8 34.7 46.2 31.7 13.4 34.9 33.1 14.2 19.9 25.4 13.4 30.4 29.6 19.0 166.2 33.6 14.7 32.0 44.7 21.5 19.3 19.6 26.3 13.8 17.2 45.5 24.5 35.9 27.8 15.3 4.6 10.5 7.4 5.7 7.4 5.4 5.2 5.8 4.6 5.1 5.1 4.6 7.7 8.8 6.9 7.9 6.3 3.9 21.9 26.9 16.9 22.0 17.4 24.9 18.4 24.2 20.4 17.9 25.2 27.3 79.1 214.7 186.1 37.5 70.9 40.7 65.6 44.2 34.7 84.6 47.3 63.5 164.0 90.1 89.0 55.2 43.8 88.3 75.8 43.6 27.4 64.5 4.2 67.0 114.7 82.7 55.6 117.6 69.4 48.6 78.6 76.2 29.6 79.8 129.3 64.1 75.7 269.2 63.5 85.8 71.2 42.4 40.7 82.5 31.4 11.8 76.7 66.0 28.4 48.7 90.2 87.1 112.3 55.3 149.5 54.7 38.7 81.6 44.0 60.9 34.4 19.5 83.9 69.2 52.6 120.2 99.4 183.6 106.0 37.7 50.6 80.3 80.8 66.9 49.7 54.5 ZCCHC17 "HSPC251, pNO40, PS1D" ENSG00000121766 "Zinc finger CCHC-type containing 17" Q9NP64 1 31296982-31364953 "Predicted intracellular proteins" Ribonucleoprotein "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 249.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053727 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA053727: AB_2732581" "unprognostic (1.49e-3)" "unprognostic (1.47e-2)" "unprognostic (1.04e-1)" "unprognostic (8.72e-3)" "unprognostic (2.01e-1)" "unprognostic (3.81e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.18e-1)" "unprognostic (4.43e-2)" "unprognostic (1.00e-3)" "unprognostic (2.70e-1)" "unprognostic (2.43e-1)" "unprognostic (2.40e-1)" "unprognostic (1.44e-1)" "unprognostic (8.41e-2)" "unprognostic (4.88e-2)" "unprognostic (2.17e-1)" 22.3 26.9 69.7 16.9 71.0 19.2 29.7 63.0 92.1 21.7 50.1 25.1 12.5 21.3 57.8 21.9 20.6 15.0 51.7 73.8 72.0 31.7 16.9 18.2 21.3 68.7 75.4 19.7 17.8 23.6 26.1 21.3 74.1 21.8 19.9 37.9 19.7 26.4 32.1 23.3 18.5 22.7 69.7 20.6 20.4 48.1 68.1 26.9 21.0 24.2 25.9 23.6 20.8 77.5 42.5 35.4 59.4 38.9 55.5 46.4 34.8 63.7 56.1 71.4 64.5 58.0 38.0 45.3 48.2 48.5 31.3 30.6 67.9 59.9 81.2 29.8 45.4 60.5 53.5 66.4 46.5 56.1 25.1 34.0 60.8 81.7 84.1 50.9 77.6 48.7 64.8 26.8 65.6 35.6 48.8 59.1 105.8 51.8 61.3 46.0 81.4 41.3 78.2 42.2 42.7 26.7 54.7 43.9 205.9 87.9 32.2 34.9 52.7 36.1 38.8 83.1 66.2 26.0 45.1 55.6 49.1 69.4 103.5 87.1 35.8 60.2 41.0 38.5 36.9 39.7 41.1 43.1 35.9 47.7 37.7 45.5 12.2 36.6 38.3 40.7 42.2 52.3 69.7 71.0 63.0 92.1 73.8 72.0 68.7 75.4 74.1 69.7 68.1 77.5 38.1 19.2 23.7 25.5 31.6 31.0 36.4 55.1 20.5 52.8 34.8 43.3 61.6 31.5 37.0 27.6 27.1 87.7 48.7 24.7 72.4 54.3 80.4 37.4 39.8 41.3 24.7 48.0 46.9 52.4 71.8 33.3 13.7 41.9 41.8 50.2 36.4 24.3 54.2 85.8 41.3 28.5 32.6 26.8 30.8 122.7 42.9 50.6 35.6 24.4 56.5 71.5 69.0 39.2 33.2 54.8 35.4 53.8 27.8 54.0 22.3 64.7 29.2 53.8 46.0 35.5 50.5 249.2 177.6 28.7 34.2 83.9 41.8 45.3 29.4 58.6 ZCCHC9 "DKFZp761J139, PPP1R41" ENSG00000131732 "Zinc finger CCHC-type containing 9" Q8N567 5 81301587-81313297 "Predicted intracellular proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 146.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038404 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Nucleoli "HPA038404: AB_10672744" "unprognostic (1.55e-1)" "unprognostic (2.27e-1)" "unprognostic (1.31e-2)" "unprognostic (1.43e-2)" "unprognostic (1.57e-2)" "unprognostic (1.71e-2)" "unprognostic (6.29e-2)" "unprognostic (4.91e-2)" "unprognostic (1.10e-1)" "unprognostic (3.31e-1)" "unprognostic (3.58e-2)" "unprognostic (2.68e-2)" "unprognostic (5.20e-3)" "unprognostic (1.60e-1)" "unprognostic (2.05e-1)" "unprognostic (1.29e-1)" "unprognostic (1.06e-1)" 13.4 12.3 8.7 15.9 8.6 10.8 13.5 9.7 13.4 15.5 9.8 15.2 14.9 15.5 16.3 14.6 12.6 14.3 11.2 8.6 9.2 17.9 33.3 11.2 19.0 8.9 9.0 17.2 11.8 13.0 13.8 19.1 9.0 15.5 14.9 14.0 10.5 11.0 14.9 16.3 18.7 14.6 8.5 13.3 12.9 14.9 9.4 17.7 12.6 11.6 18.2 16.3 13.5 9.1 26.6 18.5 44.5 23.7 37.5 35.3 59.7 39.2 46.3 29.5 40.8 41.0 35.8 24.6 15.8 19.8 51.1 19.4 35.6 35.8 46.9 55.3 33.5 25.4 21.0 48.4 44.2 32.6 20.3 27.6 30.7 25.3 62.7 22.9 25.3 26.5 43.1 23.4 30.8 36.3 54.0 48.7 32.4 14.9 23.7 31.9 57.0 36.4 23.4 26.5 21.6 20.5 31.1 18.4 146.5 32.1 23.0 51.7 17.6 18.5 22.6 33.2 43.4 33.2 36.5 37.7 32.7 46.7 40.3 12.6 10.8 11.3 10.5 14.9 13.2 12.8 14.0 12.8 13.3 11.1 13.3 13.8 10.6 10.8 13.6 15.1 17.4 6.5 8.7 8.6 9.7 13.4 8.6 9.2 8.9 9.0 9.0 8.5 9.4 9.1 15.9 9.6 18.6 10.4 18.2 9.1 12.5 25.8 14.2 18.0 14.5 17.1 12.3 37.1 19.3 31.3 14.6 28.0 17.3 15.0 31.3 22.4 68.4 22.6 31.5 17.9 7.8 12.8 15.0 20.4 53.8 23.9 14.8 18.8 13.3 13.3 29.6 61.7 36.7 26.9 19.3 23.3 16.2 14.2 16.5 19.1 32.6 19.9 3.6 13.1 33.2 22.0 35.0 12.1 14.2 30.2 27.4 29.0 17.6 13.8 44.8 67.1 28.1 28.2 19.7 16.2 18.8 75.6 38.2 14.0 9.2 23.0 19.8 22.3 21.6 12.6 ZFAND6 "AWP1, ZA20D3, ZFAND5B" ENSG00000086666 "Zinc finger AN1-type containing 6" Q6FIF0 15 80059568-80138393 "Predicted intracellular proteins" "Apoptosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 496.7;Late spermatids: 598.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034845, HPA052746, HPA077824" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA034845: AB_10671234, HPA052746: , HPA077824: " "unprognostic (2.04e-1)" "unprognostic (2.25e-2)" "unprognostic (3.26e-1)" "unprognostic (2.31e-1)" "unprognostic (1.29e-1)" "unprognostic (3.70e-2)" "unprognostic (4.26e-2)" "unprognostic (1.03e-1)" "unprognostic (4.91e-2)" "unprognostic (1.22e-1)" "unprognostic (1.74e-2)" "unprognostic (6.48e-3)" "unprognostic (4.90e-3)" "unprognostic (1.22e-1)" "unprognostic (1.45e-1)" "unprognostic (1.55e-1)" "prognostic favorable (8.20e-4)" 63.2 70.2 41.3 48.4 43.1 79.9 65.4 54.5 48.8 47.8 48.7 61.5 54.8 58.2 66.2 54.9 54.9 49.8 90.5 42.1 50.1 76.3 123.5 55.7 73.2 50.6 46.4 40.8 42.1 60.6 41.2 50.6 47.7 56.3 61.1 74.2 52.9 50.6 128.5 44.0 53.9 59.8 53.7 60.9 59.6 135.9 44.0 50.9 100.9 109.8 75.5 55.2 43.1 57.2 78.9 161.0 116.9 67.3 118.0 93.4 110.3 91.7 127.2 78.7 107.0 56.6 133.6 87.5 115.7 94.3 76.6 63.1 125.9 92.3 83.8 52.8 107.2 207.1 72.7 78.5 138.2 74.7 131.9 83.3 117.8 87.3 117.7 108.3 120.0 74.4 84.5 66.8 87.3 83.3 59.5 74.0 73.6 70.3 53.4 48.1 102.6 200.8 196.3 129.4 23.9 68.8 79.2 91.0 238.4 144.5 89.1 106.7 111.5 82.1 66.5 53.2 89.8 88.9 189.1 102.6 85.0 127.1 58.6 505.1 90.0 290.1 93.6 118.9 82.5 226.4 84.7 91.2 103.1 174.4 88.2 98.4 216.3 85.0 167.1 89.5 91.2 135.7 41.3 43.1 54.5 48.8 42.1 50.1 50.6 46.4 47.7 53.7 44.0 57.2 60.5 54.5 86.8 76.0 122.5 149.5 141.3 236.1 46.7 40.3 96.2 60.1 92.7 85.8 147.8 75.4 41.7 125.3 101.1 95.9 199.6 103.7 496.7 102.0 57.0 75.0 82.6 97.2 18.1 98.3 130.8 75.0 69.8 135.3 105.1 57.0 72.8 154.6 144.2 32.0 27.7 88.6 203.4 96.1 173.5 598.2 53.1 109.8 124.5 78.7 167.2 101.3 91.6 61.9 73.9 126.5 107.6 62.8 92.7 174.1 64.8 278.8 168.3 89.9 92.1 70.0 98.6 230.6 173.3 62.8 169.3 392.8 87.0 67.6 67.3 183.4 ZFYVE16 "KIAA0305, PPP1R69" ENSG00000039319 "Zinc finger FYVE-type containing 16" Q7Z3T8 5 80408013-80483379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 182.0;Oligodendrocytes: 620.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 21.2;neutrophil: 21.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 80.7" "Low region specificity" "Detected in all" "HPA035935, HPA035936" Supported Enhanced Vesicles,Cytosol No No "Cluster 6: Non-specific - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "Vesicles, Cytosol" "HPA035935: AB_10672076, HPA035936: AB_10669662" "unprognostic (1.11e-1)" "unprognostic (3.98e-2)" "unprognostic (1.78e-2)" "unprognostic (3.26e-1)" "unprognostic (7.19e-2)" "unprognostic (2.57e-2)" "unprognostic (7.25e-3)" "unprognostic (6.91e-2)" "unprognostic (4.00e-1)" "unprognostic (8.83e-2)" "unprognostic (1.29e-1)" "unprognostic (2.15e-1)" "unprognostic (3.04e-1)" "unprognostic (4.64e-2)" "unprognostic (4.95e-2)" "unprognostic (6.91e-2)" "unprognostic (4.23e-2)" 8.4 8.7 5.1 8.1 12.0 5.2 8.7 5.7 6.4 15.1 4.3 6.4 5.1 12.7 2.5 7.2 7.2 11.2 14.0 4.1 8.2 9.5 10.3 9.1 5.6 7.0 8.5 12.3 6.4 9.0 3.9 13.0 7.6 8.5 6.3 8.6 5.0 6.6 6.1 4.3 6.8 9.9 6.5 9.0 6.6 9.3 8.3 5.0 9.5 8.4 4.5 9.5 4.7 15.5 11.9 13.4 23.4 21.9 14.0 14.3 15.5 17.6 15.2 15.4 20.7 9.9 16.5 7.9 12.5 14.6 16.4 11.9 17.2 14.4 16.9 5.1 10.9 8.6 16.3 11.3 11.6 2.6 6.3 15.4 7.5 12.9 12.4 12.4 18.0 7.3 8.5 12.0 16.8 14.9 5.7 2.5 5.3 6.1 6.5 11.7 48.3 8.4 12.9 22.1 8.8 19.5 25.3 11.6 80.7 14.1 20.2 7.7 16.0 9.2 10.3 14.3 14.6 3.6 7.6 7.8 12.1 8.0 21.0 21.2 4.5 2.5 1.8 2.8 1.0 3.6 0.9 1.6 1.8 3.2 0.7 0.9 21.3 3.0 5.4 3.0 1.0 0.4 5.1 12.0 5.7 6.4 4.1 8.2 7.0 8.5 7.6 6.5 8.3 15.5 49.3 25.6 22.2 127.0 25.8 18.2 14.0 16.4 15.4 94.9 23.4 18.2 52.3 14.3 33.8 31.3 114.7 22.1 28.9 20.3 9.8 16.2 7.4 47.6 85.6 33.1 21.6 7.8 87.7 12.3 11.8 33.7 23.9 37.5 10.1 59.7 35.7 16.8 26.5 80.8 114.0 11.3 2.0 59.8 71.5 7.0 37.9 71.4 19.6 64.6 34.7 26.3 17.5 182.0 620.2 16.4 20.2 44.4 19.0 16.5 16.3 13.6 49.9 75.3 32.9 58.6 43.3 49.0 22.0 15.6 25.4 37.4 17.5 44.7 12.9 20.1 ZMYND12 DKFZp434N2435 ENSG00000066185 "Zinc finger MYND-type containing 12" Q9H0C1 1 42430329-42456253 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 17.1;testis: 28.8" "Cell type enhanced" "Detected in many" "Early spermatids: 164.2;Late spermatids: 71.4;Respiratory ciliated cells: 40.0;Spermatocytes: 95.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 2.6;SK-MEL-30: 2.2;WM-115: 1.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (4.54e-2)" "unprognostic (1.57e-1)" "unprognostic (2.20e-1)" "unprognostic (6.43e-3)" "unprognostic (2.53e-3)" "unprognostic (8.13e-2)" "unprognostic (4.89e-2)" "unprognostic (2.79e-3)" "unprognostic (7.23e-2)" "unprognostic (2.17e-1)" "unprognostic (2.51e-1)" "unprognostic (1.87e-2)" "prognostic favorable (1.11e-5)" "unprognostic (1.76e-1)" "unprognostic (2.27e-2)" "unprognostic (1.52e-1)" "unprognostic (1.45e-1)" 1.0 2.3 4.6 0.2 4.4 0.2 2.2 4.3 5.6 2.0 5.7 1.2 1.0 1.3 9.4 0.3 17.1 1.8 2.3 4.2 5.1 9.3 6.9 1.9 0.4 5.6 7.1 1.9 3.3 2.3 3.4 0.5 5.4 2.3 1.1 4.1 1.0 2.1 1.8 0.7 0.4 0.9 5.0 0.9 1.6 28.8 4.9 0.6 5.0 2.5 0.3 0.9 0.3 5.0 0.0 0.0 0.2 0.8 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.8 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.4 0.0 0.0 0.1 0.0 0.5 0.4 0.0 0.5 2.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.4 1.7 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.3 4.6 4.4 4.3 5.6 4.2 5.1 5.6 7.1 5.4 5.0 4.9 5.0 0.4 3.2 2.7 4.6 0.5 0.0 0.8 2.6 0.0 0.9 2.5 1.8 3.7 7.2 4.3 7.3 0.0 1.5 0.3 0.6 15.6 1.0 164.2 26.3 1.0 0.5 0.0 1.3 1.6 0.5 1.3 1.3 4.1 1.8 0.0 1.1 0.4 3.8 2.6 0.0 1.7 1.5 6.1 2.6 0.0 71.4 2.5 3.7 3.6 2.8 0.8 3.5 1.0 1.0 1.6 0.1 0.3 2.2 0.8 0.5 0.9 18.4 40.0 2.8 0.0 1.0 0.5 95.9 5.4 0.8 0.3 0.7 0.4 1.9 0.7 1.1 ZNF322 "bA457M11.2, bA457M11.3, HCG12, ZNF322A, ZNF388, ZNF489" ENSG00000181315 "Zinc finger protein 322" Q6U7Q0 6 26634383-26659752 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043161, HPA046692" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Centrosome, Cytosol" "HPA043161: AB_2678346, HPA046692: AB_2679755" "unprognostic (1.01e-2)" "unprognostic (2.81e-1)" "unprognostic (5.20e-2)" "unprognostic (3.39e-3)" "prognostic favorable (1.28e-4)" "unprognostic (1.21e-1)" "unprognostic (9.35e-2)" "prognostic favorable (8.57e-4)" "unprognostic (5.24e-2)" "unprognostic (3.52e-2)" "unprognostic (2.53e-1)" "unprognostic (2.50e-1)" "unprognostic (1.73e-1)" "unprognostic (1.08e-1)" "unprognostic (3.55e-1)" "unprognostic (3.24e-2)" "unprognostic (5.71e-2)" 7.8 12.0 11.0 7.8 11.9 1.3 12.8 12.1 12.4 15.4 10.9 8.8 9.3 15.5 13.3 8.6 11.4 9.8 7.7 10.2 12.0 11.8 9.3 9.9 9.9 11.8 11.5 17.9 8.2 17.7 7.1 11.2 12.4 14.9 10.9 14.3 8.7 13.9 6.6 6.0 8.1 10.5 12.0 11.7 9.1 11.1 11.6 10.1 15.3 12.8 9.7 10.8 7.4 15.0 9.3 6.8 26.2 31.0 17.3 22.5 9.7 12.3 16.1 16.6 20.1 13.3 5.5 11.0 28.5 10.6 20.8 11.5 19.7 7.4 20.8 17.3 18.0 19.5 8.7 13.2 19.5 0.0 17.3 14.1 27.0 10.7 12.3 20.8 14.4 13.5 23.3 11.7 18.3 5.2 14.1 16.9 7.8 8.5 8.4 15.4 18.6 16.0 10.1 14.5 21.3 22.7 14.5 13.6 25.9 12.8 12.5 12.8 14.4 27.8 11.0 11.4 12.4 12.2 25.8 10.8 5.8 2.9 28.4 3.3 8.4 10.8 10.5 7.2 7.6 11.2 5.3 6.9 6.9 9.0 6.1 9.1 8.0 17.8 11.9 7.8 4.5 5.1 11.0 11.9 12.1 12.4 10.2 12.0 11.8 11.5 12.4 12.0 11.6 15.0 24.8 6.4 10.5 3.9 18.0 4.0 17.3 4.8 14.8 32.1 23.9 31.2 5.8 12.8 11.1 9.2 8.4 12.5 16.1 9.9 35.2 17.7 4.1 14.2 32.6 20.1 19.7 7.2 5.3 10.2 11.3 21.9 10.2 15.7 13.3 30.0 18.2 7.6 13.3 47.1 7.0 14.1 8.2 8.9 5.3 3.7 30.1 11.7 8.8 6.5 12.7 26.7 10.3 11.1 10.3 16.1 12.8 26.4 11.8 26.4 10.2 13.3 8.1 13.9 32.9 20.6 22.2 26.0 15.7 12.0 6.5 9.6 9.1 37.7 10.0 24.9 ZNF697 MGC45731 ENSG00000143067 "Zinc finger protein 697" Q5TEC3 1 119619377-119648266 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.0;Syncytiotrophoblasts: 19.8" "Cancer enhanced" "Detected in all" "melanoma: 14.4" "Region enhanced" "Detected in some" "basal ganglia: 3.3;cerebral cortex: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 42.8;WM-115: 42.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049933 Uncertain Approved Nucleoplasm NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA049933: AB_2680958" "unprognostic (2.57e-1)" "unprognostic (7.02e-3)" "unprognostic (4.32e-2)" "unprognostic (2.45e-2)" "unprognostic (3.38e-1)" "unprognostic (9.79e-3)" "unprognostic (1.20e-3)" "unprognostic (1.30e-3)" "unprognostic (2.82e-1)" "unprognostic (1.45e-1)" "unprognostic (5.09e-2)" "unprognostic (1.14e-1)" "prognostic favorable (6.20e-5)" "unprognostic (1.19e-2)" "unprognostic (6.48e-2)" "unprognostic (3.53e-2)" "unprognostic (3.36e-1)" 4.1 2.9 0.9 1.4 3.3 1.0 3.4 0.0 3.2 1.5 0.0 1.3 1.7 2.2 2.3 0.8 1.4 1.5 4.3 1.5 0.0 7.5 3.1 4.4 0.6 0.0 0.0 2.0 2.8 4.9 2.8 6.9 0.0 4.2 1.4 0.9 5.4 1.0 2.1 1.6 1.5 1.2 0.0 1.4 1.8 3.1 0.2 0.5 3.2 1.9 0.4 2.0 1.0 0.0 2.0 1.0 4.9 1.6 6.4 7.0 6.6 8.8 12.2 5.1 4.6 3.1 0.4 0.0 2.9 4.9 4.0 2.2 3.8 8.7 11.9 0.0 3.8 3.3 2.0 5.9 12.2 2.2 2.2 11.9 2.4 11.4 24.2 5.6 10.1 2.8 3.0 0.4 2.3 1.5 0.0 1.6 26.1 1.8 2.9 0.0 11.8 0.2 2.4 4.5 1.1 6.8 2.0 2.1 42.8 15.4 1.0 3.1 23.4 8.4 10.7 6.0 15.4 1.2 2.0 0.0 11.9 2.3 42.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 3.3 0.0 3.2 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.5 1.3 0.1 2.2 1.5 2.5 0.6 0.8 1.7 0.6 8.8 1.5 1.9 1.8 0.0 7.9 0.0 0.7 3.9 1.8 1.6 1.1 2.6 3.5 2.4 0.0 17.0 0.9 2.3 4.3 1.5 1.8 0.0 5.5 3.3 4.2 2.6 0.0 6.9 2.1 4.1 3.7 12.0 3.6 4.7 3.1 5.4 4.7 2.7 1.1 0.0 8.0 0.6 2.1 3.3 6.4 0.0 3.7 1.8 6.4 0.4 0.9 6.6 0.5 5.4 1.3 1.5 0.4 1.8 19.8 0.1 5.3 1.8 0.9 ZNF706 HSPC038 ENSG00000120963 "Zinc finger protein 706" Q9Y5V0 8 101177878-101206193 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1090.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042793 Approved "Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA042793: AB_10795710" "unprognostic (2.05e-2)" "unprognostic (3.29e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (3.12e-5)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "unprognostic (2.48e-3)" "unprognostic (5.22e-2)" "unprognostic (3.19e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (5.90e-11)" "unprognostic (9.65e-2)" "unprognostic (1.59e-1)" "unprognostic (3.57e-1)" "unprognostic (2.17e-2)" 99.5 83.4 85.6 57.3 85.3 76.9 92.6 89.1 114.7 86.7 54.6 93.3 93.3 71.5 90.4 147.2 69.0 69.2 86.0 87.2 72.9 95.9 96.0 81.9 95.5 69.0 72.8 70.2 269.9 69.8 93.9 55.3 69.6 70.9 87.2 46.9 99.1 49.1 110.7 180.0 100.0 50.7 69.7 100.5 92.7 118.1 70.0 67.2 82.3 86.1 102.5 75.1 101.1 83.1 203.0 113.9 196.0 62.7 69.0 78.0 124.8 82.4 105.5 83.5 89.0 81.8 121.5 121.9 139.4 99.1 170.4 108.4 113.3 111.0 95.8 90.5 98.0 122.1 69.5 159.2 90.7 92.2 114.1 69.1 170.9 78.9 170.7 115.1 144.0 121.4 134.8 230.6 75.0 142.6 194.5 252.2 59.7 408.6 278.8 80.8 65.3 251.1 112.7 103.2 129.4 57.6 57.6 95.0 375.9 166.3 99.3 96.5 96.3 45.6 93.9 121.9 87.0 194.1 202.6 197.0 123.5 199.2 215.8 255.1 280.0 162.6 138.0 463.2 143.4 400.0 191.5 178.0 264.1 344.1 214.7 206.3 38.7 130.9 492.1 532.8 302.8 268.7 85.6 85.3 89.1 114.7 87.2 72.9 69.0 72.8 69.6 69.7 70.0 83.1 131.4 60.9 41.0 29.0 188.6 459.7 242.3 252.7 149.7 59.3 159.3 182.6 79.8 137.2 138.1 79.1 18.8 190.6 175.0 288.4 180.0 264.5 439.7 125.5 70.1 137.7 265.1 107.1 31.5 259.8 339.0 131.4 106.5 114.9 122.2 85.1 99.2 123.4 265.3 85.8 21.1 275.3 231.9 162.3 186.4 1090.7 86.9 214.8 206.3 16.9 298.4 131.3 114.4 14.6 57.6 401.5 265.4 86.9 329.4 326.5 339.2 195.1 110.8 55.9 105.2 111.6 169.8 84.3 82.7 224.8 518.0 193.3 112.7 72.7 153.5 311.7 ZXDC "FLJ13861, MGC11349" ENSG00000070476 "ZXD family zinc finger C" Q2QGD7 3 126437601-126475891 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.4" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Oligodendrocyte precursor cells: 67.8;Oligodendrocytes: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.4" "Group enriched" "Detected in many" 4 "dendritic cells: 1.1;granulocytes: 1.7;monocytes: 4.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049593 Approved Nucleoli Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoli "HPA049593: AB_2680828" "unprognostic (3.06e-1)" "unprognostic (2.00e-2)" "unprognostic (2.65e-1)" "unprognostic (2.81e-3)" "unprognostic (1.59e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (2.27e-4)" "unprognostic (3.06e-2)" "unprognostic (5.97e-2)" "unprognostic (4.34e-2)" "unprognostic (3.37e-2)" "unprognostic (2.67e-2)" "unprognostic (1.06e-1)" "unprognostic (8.13e-2)" "unprognostic (2.98e-1)" "unprognostic (4.66e-2)" "unprognostic (1.12e-3)" 6.9 5.2 6.8 6.2 9.4 39.4 6.3 8.7 9.6 8.1 9.2 5.3 5.0 7.8 5.2 7.3 8.8 6.0 5.6 6.6 5.9 6.3 7.6 7.0 7.9 9.6 8.1 10.7 14.9 10.1 3.9 7.5 8.7 7.2 5.4 7.6 8.0 6.6 16.2 9.7 5.9 6.5 6.7 8.8 6.7 6.4 8.3 10.0 8.5 9.8 6.0 6.1 5.6 14.4 15.2 7.6 9.4 8.9 10.1 7.8 16.7 6.7 7.4 9.7 8.6 11.6 6.4 11.2 11.2 6.1 8.9 12.3 12.6 7.9 7.6 6.0 10.8 8.8 9.2 7.7 10.7 13.6 13.7 6.2 15.1 6.0 10.6 9.6 10.0 13.0 9.6 14.6 8.2 8.9 13.1 7.5 13.4 10.0 7.6 14.1 6.4 14.3 6.8 10.9 17.1 9.5 13.0 9.5 18.2 6.2 12.9 11.9 10.2 8.9 11.4 13.4 8.3 12.1 6.1 14.6 9.7 10.5 10.0 1.7 0.4 0.8 0.5 0.2 0.2 0.1 0.3 0.4 0.7 0.4 0.5 0.4 1.2 0.3 4.4 1.1 0.2 0.2 6.8 9.4 8.7 9.6 6.6 5.9 9.6 8.1 8.7 6.7 8.3 14.4 10.1 25.6 15.6 84.5 11.9 6.2 8.3 4.5 10.8 30.1 6.8 6.5 5.5 12.8 7.9 5.5 45.9 7.2 10.0 8.6 7.9 4.8 1.7 8.1 7.9 7.7 3.6 12.0 51.3 6.1 2.6 7.8 9.2 12.2 2.5 16.8 7.9 14.3 5.7 13.5 44.3 6.9 0.0 5.4 4.4 0.8 7.5 9.0 1.8 47.8 7.3 23.0 7.2 67.8 99.2 4.4 5.2 7.5 12.9 6.0 8.4 9.5 7.7 30.4 0.0 13.5 8.9 3.3 9.0 9.0 4.3 6.3 11.1 10.5 6.6 6.3