Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A4GALT "A14GALT, Gb3S, P(k), P1" ENSG00000128274 "Alpha 1,4-galactosyltransferase (P blood group)" Q9NPC4 22 42692121-42721298 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 70.7;Proximal tubular cells: 91.0;Urothelial cells: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 38.7;ASC TERT1: 31.3;RPTEC TERT1: 27.1;TIME: 29.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001141 Uncertain Mitochondria NA NA 22000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA001141: AB_1078139" "unprognostic (2.59e-2)" "prognostic favorable (2.48e-4)" "unprognostic (2.24e-2)" "unprognostic (4.54e-3)" "unprognostic (7.41e-2)" "unprognostic (1.53e-1)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.28e-1)" "unprognostic (4.82e-3)" "unprognostic (4.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (8.72e-2)" "unprognostic (3.46e-2)" "unprognostic (2.74e-1)" 41.5 14.3 6.2 6.1 6.0 4.1 31.3 5.0 8.0 29.6 8.0 30.9 4.5 28.1 3.3 30.6 29.2 4.4 77.0 6.2 5.3 51.3 4.3 26.0 6.8 7.8 5.8 7.8 6.2 1.2 16.7 9.1 5.6 35.1 1.7 0.3 36.1 21.3 19.4 20.8 18.2 6.9 6.0 16.2 26.6 6.2 7.1 1.6 25.1 6.3 5.1 38.1 38.2 6.0 1.2 13.6 0.0 0.0 38.7 31.3 20.1 5.5 5.8 1.2 2.1 4.3 2.2 13.6 9.4 9.7 6.7 1.3 12.9 6.5 0.2 0.0 2.7 0.3 21.1 0.5 11.5 0.0 0.9 18.6 1.8 5.5 0.9 1.8 4.7 0.0 0.1 0.0 5.1 19.0 0.0 0.0 1.6 0.9 3.3 0.0 3.0 1.4 27.1 23.4 0.2 0.0 16.9 0.3 0.0 2.4 10.6 1.6 29.3 0.0 2.6 24.3 7.3 2.8 13.1 0.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 6.2 6.0 5.0 8.0 6.2 5.3 7.8 5.8 5.6 6.0 7.1 6.0 47.1 0.0 0.5 0.3 1.6 9.2 28.9 70.7 0.0 0.1 4.2 1.5 15.8 1.5 41.2 18.4 0.0 48.7 0.4 0.2 13.7 23.1 0.7 11.1 10.3 43.7 0.0 10.7 0.1 1.1 35.3 43.8 2.6 17.4 1.3 0.2 30.7 0.2 5.3 0.0 0.1 0.0 14.2 1.0 11.8 4.4 46.3 4.0 7.2 7.5 30.0 0.8 0.0 0.5 0.0 3.6 0.0 30.1 0.1 40.1 0.0 91.0 12.1 0.6 39.5 7.6 29.3 0.6 0.6 1.2 8.8 9.4 1.5 19.9 0.1 74.7 ABCA8 KIAA0822 ENSG00000141338 "ATP binding cassette subfamily A member 8" O94911 17 68867289-68955392 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 231.5;Granulosa cells: 117.3;Leydig cells: 502.6;Microglial cells: 162.1;Oligodendrocytes: 406.6;Skeletal myocytes: 216.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 31.9;ASC TERT1: 69.6;HSkMC: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044914 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044914: AB_10964859" "unprognostic (2.58e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.04e-1)" "unprognostic (6.84e-2)" "unprognostic (1.47e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (5.22e-2)" "unprognostic (6.68e-2)" "unprognostic (8.76e-2)" "unprognostic (1.42e-3)" "unprognostic (3.52e-3)" "unprognostic (1.88e-1)" "unprognostic (3.29e-1)" "unprognostic (6.14e-3)" 39.1 30.5 12.6 2.8 28.1 0.0 21.3 21.0 18.3 10.0 9.6 16.4 6.2 11.9 15.6 7.6 23.7 16.9 42.1 13.6 16.1 9.5 33.7 18.2 1.1 28.2 19.8 51.5 5.7 3.8 11.1 9.0 29.0 9.5 16.9 9.2 14.8 8.6 12.3 6.2 11.8 6.6 20.7 12.4 14.3 19.5 18.4 4.5 17.0 26.7 3.0 16.3 14.6 58.1 0.0 0.0 3.9 0.0 31.9 69.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 12.0 0.0 0.0 53.5 0.0 0.8 0.0 0.4 6.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 28.1 21.0 18.3 13.6 16.1 28.2 19.8 29.0 20.7 18.4 58.1 22.6 51.3 1.1 0.7 0.0 6.0 1.8 0.0 2.8 5.0 0.7 1.0 18.8 0.0 4.3 0.0 2.1 0.2 0.3 0.0 0.0 0.0 4.8 0.4 14.0 6.8 0.0 0.0 0.5 0.0 0.1 231.5 3.1 0.3 1.3 117.3 5.7 48.1 1.1 5.0 0.6 0.0 0.0 1.9 9.4 19.4 502.6 2.6 1.8 162.1 0.0 100.3 0.0 0.5 406.6 0.0 0.0 70.3 1.9 0.4 0.0 0.1 0.0 3.3 39.5 216.6 44.5 5.1 1.7 2.5 4.7 0.3 2.1 60.9 0.0 0.4 ABCA9 EST640918 ENSG00000154258 "ATP binding cassette subfamily A member 9" Q8IUA7 17 68974488-69060949 "Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 55.5;Fibroblasts: 86.6;Inhibitory neurons: 73.2;Leydig cells: 96.3;Microglial cells: 227.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 21.8;ASC TERT1: 47.7;HSkMC: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052113, HPA054823" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA052113: AB_2732573, HPA054823: AB_2682615" "unprognostic (3.88e-2)" "unprognostic (9.86e-2)" "unprognostic (2.21e-1)" "unprognostic (9.75e-2)" "unprognostic (4.46e-1)" "unprognostic (5.64e-3)" "unprognostic (4.51e-4)" "unprognostic (1.83e-2)" "unprognostic (1.94e-3)" "unprognostic (7.86e-2)" "unprognostic (3.26e-3)" "unprognostic (3.51e-1)" "unprognostic (7.77e-6)" "unprognostic (5.32e-4)" "unprognostic (7.22e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-3)" 33.7 4.1 2.8 1.4 5.1 1.8 22.3 7.7 8.0 14.7 6.3 12.4 1.8 11.2 8.9 4.8 20.6 8.2 22.6 3.0 1.4 2.7 11.9 8.8 2.3 3.1 1.2 27.4 3.5 2.3 4.9 1.2 4.5 3.3 4.0 8.4 9.0 2.8 13.1 9.2 6.6 6.6 1.2 1.6 7.8 5.2 3.5 2.5 11.1 10.6 1.1 10.9 12.7 7.7 0.2 0.4 0.8 0.8 21.8 47.7 0.6 0.4 0.4 0.0 0.4 0.5 0.5 0.6 0.2 0.8 0.3 0.5 0.4 0.7 0.2 0.3 0.4 0.6 2.4 0.6 2.3 0.9 1.3 17.0 0.5 3.6 0.3 0.9 4.8 0.6 0.8 1.3 0.1 0.3 0.3 2.1 0.3 0.2 0.4 2.2 0.1 0.3 0.3 1.9 0.7 0.6 0.5 0.3 0.3 0.4 0.4 0.8 2.0 1.3 0.5 2.3 0.5 1.0 0.5 0.4 0.4 0.5 2.4 0.5 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.2 0.2 0.4 0.2 0.0 0.1 0.0 0.0 2.8 5.1 7.7 8.0 3.0 1.4 3.1 1.2 4.5 1.2 3.5 7.7 7.4 0.0 1.5 2.6 0.5 1.8 0.3 0.1 1.2 3.9 0.7 0.8 3.9 1.5 0.1 0.0 0.0 0.0 0.6 0.9 0.0 0.1 1.3 0.4 2.1 2.6 0.0 0.0 55.5 0.0 0.0 86.6 2.0 1.4 0.0 2.2 18.5 11.4 0.3 0.0 73.2 0.1 0.0 1.3 5.1 3.6 96.3 4.9 0.0 227.7 0.0 7.9 1.0 6.0 10.9 0.2 0.0 15.4 0.2 0.1 0.3 0.0 1.7 5.6 13.1 26.3 7.1 1.3 0.8 1.3 1.6 0.0 0.5 26.3 0.1 0.3 ABCC9 "CMD1O, SUR2" ENSG00000069431 "ATP binding cassette subfamily C member 9" O60706 12 21797389-21942529 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport Receptor "Atrial fibrillation, Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 45.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 60.3;Astrocytes: 72.1;Hepatocytes: 99.4;Sertoli cells: 131.5;Smooth muscle cells: 140.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.9;BJ hTERT+: 14.0;CACO-2: 20.8;HSkMC: 27.1;U-138 MG: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007279 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA007279: AB_1844435" "unprognostic (4.82e-2)" "unprognostic (3.62e-2)" "unprognostic (5.51e-4)" "unprognostic (1.09e-1)" "unprognostic (1.09e-1)" "unprognostic (8.30e-2)" "unprognostic (3.17e-2)" "unprognostic (1.50e-2)" "unprognostic (2.47e-2)" "unprognostic (8.72e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-1)" "prognostic unfavorable (1.85e-5)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (3.10e-3)" "unprognostic (8.22e-5)" 27.4 5.9 4.5 3.4 5.4 1.7 9.2 3.1 9.2 8.2 11.6 7.4 4.0 19.1 8.3 6.2 12.3 11.7 28.3 5.4 3.6 6.6 45.2 7.7 3.5 4.8 7.4 10.9 3.5 1.9 2.2 3.6 3.7 7.9 1.8 3.2 4.5 9.9 41.9 4.2 3.1 21.0 3.4 4.4 8.1 1.2 5.1 1.8 6.3 30.3 1.5 5.3 5.1 7.2 0.9 0.2 11.9 0.3 24.9 11.0 0.3 6.1 14.0 7.0 3.5 20.8 1.0 0.5 1.2 0.6 0.8 0.3 0.0 0.0 7.2 0.3 0.2 0.5 0.8 0.3 0.1 0.5 0.6 27.1 0.0 6.7 2.5 0.4 0.0 0.4 0.3 1.2 0.3 1.4 0.2 0.4 1.4 1.2 0.6 0.5 0.3 0.3 0.0 1.2 0.4 1.7 0.4 0.5 0.2 1.7 1.2 0.3 0.3 27.0 1.9 2.2 8.7 1.1 1.3 0.4 6.7 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.5 5.4 3.1 9.2 5.4 3.6 4.8 7.4 3.7 3.4 5.1 7.2 33.8 35.3 60.3 72.1 0.2 3.4 1.5 5.0 0.6 0.8 0.5 0.8 38.2 0.0 25.6 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.6 0.8 20.6 19.7 0.0 0.0 17.2 0.2 0.1 26.2 1.1 0.6 24.0 0.0 7.1 99.4 0.1 1.7 1.0 0.0 0.0 2.4 5.9 0.1 0.3 2.5 10.6 2.8 0.0 15.9 0.0 1.5 1.4 0.1 0.0 0.4 0.0 0.5 0.0 0.1 20.4 1.2 131.5 11.1 140.7 0.4 1.6 1.1 2.3 0.3 2.5 0.2 0.0 2.2 ABHD14A "DKFZP564O243, DORZ1" ENSG00000248487 "Abhydrolase domain containing 14A" Q9BUJ0 3 51971426-51981199 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 124.3;Rod photoreceptor cells: 115.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 79.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038153, HPA056913" Approved Enhanced Vesicles NA NA 420000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA038153: AB_2675868, HPA056913: AB_2683275" "unprognostic (4.15e-3)" "unprognostic (6.73e-2)" "unprognostic (1.98e-1)" "unprognostic (3.34e-2)" "unprognostic (2.71e-1)" "unprognostic (1.08e-2)" "unprognostic (8.92e-2)" "prognostic favorable (4.72e-4)" "unprognostic (3.96e-1)" "unprognostic (2.46e-2)" "unprognostic (5.52e-3)" "unprognostic (1.51e-2)" "unprognostic (1.97e-2)" "unprognostic (9.74e-2)" "unprognostic (2.17e-1)" "unprognostic (1.33e-1)" "unprognostic (1.30e-2)" 23.5 48.6 65.2 8.3 64.5 13.5 18.4 72.3 78.0 25.1 67.6 18.1 10.6 15.0 28.3 8.4 24.2 12.1 36.1 64.8 69.3 35.3 26.1 14.3 11.4 59.6 60.0 27.1 26.6 27.1 49.6 8.9 59.7 19.0 6.9 43.5 23.2 14.5 34.8 7.6 12.9 7.5 59.2 14.6 17.7 13.2 69.4 11.5 32.8 39.1 8.4 19.4 16.7 59.8 6.9 12.9 8.2 24.7 79.8 39.9 4.5 9.0 14.8 10.6 14.3 14.8 27.0 7.8 6.0 22.4 12.1 6.2 9.0 10.0 3.4 25.1 10.0 22.7 37.4 50.0 22.4 31.4 29.0 37.9 6.6 9.0 4.6 23.7 13.8 14.6 9.3 25.4 16.8 7.8 14.5 31.8 4.7 32.4 30.4 10.3 4.2 73.9 20.7 10.6 16.8 26.1 22.5 4.7 13.5 1.7 7.1 33.7 8.2 9.6 10.4 23.4 10.7 37.0 37.4 6.6 18.1 49.6 14.1 6.9 20.3 15.2 94.0 12.7 96.5 49.0 80.9 83.5 36.2 41.5 73.7 79.0 2.1 45.5 8.6 46.0 88.4 54.9 65.2 64.5 72.3 78.0 64.8 69.3 59.6 60.0 59.7 59.2 69.4 59.8 15.9 6.4 21.7 0.0 20.2 9.7 25.1 29.0 4.0 90.8 21.0 22.9 24.3 20.0 20.8 33.1 25.0 10.3 29.6 7.1 33.2 15.5 4.7 23.5 18.0 14.1 40.2 2.5 0.0 12.4 15.3 36.9 4.6 14.9 15.2 12.8 17.2 16.2 29.3 58.9 0.0 14.0 24.4 14.2 18.5 24.9 88.0 14.6 12.4 0.0 7.4 59.9 41.2 0.0 0.0 17.1 5.6 33.1 16.3 17.0 13.8 124.3 29.5 115.2 19.7 24.7 16.8 18.2 57.8 1.8 5.5 4.9 28.9 20.6 15.3 19.5 ABHD15 ENSG00000168792 "Abhydrolase domain containing 15" Q6UXT9 17 29560547-29567037 "Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 26.2" "Cell type enhanced" "Detected in many" "dendritic cells: 79.4;Hepatocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.3;MAIT T-cell: 6.6;NK-cell: 10.8;plasmacytoid DC: 23.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA014470 Approved Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "HPA014470: AB_1852993" "unprognostic (1.79e-1)" "unprognostic (4.00e-2)" "unprognostic (1.38e-1)" "unprognostic (8.60e-3)" "unprognostic (1.91e-1)" "unprognostic (1.62e-1)" "unprognostic (4.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.85e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-3)" "unprognostic (3.00e-2)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (1.71e-1)" "unprognostic (3.46e-1)" "unprognostic (5.45e-2)" 19.2 3.8 3.6 6.2 4.0 8.2 10.6 3.8 3.3 4.6 3.8 7.3 11.2 4.5 3.3 4.7 4.7 5.2 4.9 3.1 4.1 8.9 26.2 6.0 9.1 4.9 4.2 2.9 8.1 7.9 9.1 4.5 4.7 4.7 6.5 1.6 5.1 3.8 2.6 4.6 11.2 4.0 4.2 9.9 8.3 1.8 4.3 4.6 5.8 3.8 8.1 5.6 4.6 4.9 5.8 22.1 2.7 7.7 29.0 12.6 11.3 7.8 8.6 7.6 6.9 5.1 2.9 8.6 5.6 8.4 13.4 15.6 9.7 3.3 4.2 26.5 7.3 3.5 11.0 6.5 8.8 9.0 15.4 9.4 8.9 7.3 1.4 5.6 5.6 5.0 4.6 8.0 4.1 7.8 8.5 10.4 0.6 19.5 6.5 19.7 10.5 20.0 13.7 8.8 1.9 3.1 11.7 5.2 3.1 2.9 13.2 20.5 6.9 4.4 5.5 11.1 7.0 13.3 9.6 4.4 8.8 5.6 9.6 18.3 0.6 2.8 2.6 0.3 6.6 1.4 1.4 2.2 1.5 2.5 0.4 1.3 0.6 10.8 0.2 23.6 1.2 1.1 3.6 4.0 3.8 3.3 3.1 4.1 4.9 4.2 4.7 4.2 4.3 4.9 2.4 3.2 4.1 2.6 11.7 1.3 1.1 2.5 2.2 0.1 3.8 2.4 3.0 2.8 4.3 7.3 0.0 1.5 79.4 12.0 0.0 3.0 0.3 4.7 3.1 2.9 7.2 7.0 0.3 7.6 1.4 4.0 2.0 5.1 2.5 2.9 4.2 30.2 7.2 1.7 0.5 6.1 2.0 6.7 8.4 0.7 4.7 9.5 5.4 2.8 5.6 1.1 15.5 0.5 1.2 5.6 2.5 4.5 5.2 1.5 17.7 5.6 5.2 0.9 0.0 3.5 1.9 0.8 0.6 2.0 2.4 0.3 11.8 4.5 7.4 1.2 ABHD4 FLJ12816 ENSG00000100439 "Abhydrolase domain containing 4, N-acyl phospholipase B" Q8TB40 14 22598237-22613215 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 35.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 35.4" "Cell line enhanced" "Detected in many" "ASC diff: 121.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000600 Uncertain Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA000600: AB_1078081" "unprognostic (5.04e-2)" "unprognostic (5.15e-2)" "unprognostic (2.68e-3)" "unprognostic (8.17e-2)" "unprognostic (1.17e-1)" "unprognostic (5.24e-2)" "unprognostic (1.19e-3)" "unprognostic (3.69e-2)" "unprognostic (1.28e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (3.73e-1)" "unprognostic (1.56e-2)" "unprognostic (5.18e-2)" "unprognostic (1.37e-1)" "unprognostic (4.51e-2)" "unprognostic (1.03e-2)" 22.8 28.7 21.6 7.3 23.6 12.6 17.5 22.3 22.4 25.9 27.7 19.2 15.0 26.3 27.4 38.3 15.4 24.7 20.5 21.0 24.5 25.3 22.6 17.6 8.0 27.8 24.5 15.9 14.5 22.8 12.8 17.9 23.3 19.3 13.8 21.7 16.5 33.7 25.5 18.9 17.9 24.5 22.5 14.8 24.9 36.8 24.2 10.1 21.6 27.2 14.8 24.8 26.2 26.0 23.4 38.5 15.5 14.2 121.8 44.0 14.9 10.3 52.2 25.3 46.8 23.5 36.4 2.2 26.7 45.2 27.2 44.5 9.9 26.6 20.6 17.3 3.5 8.7 28.1 77.9 55.6 1.4 30.3 56.1 20.6 33.2 28.2 52.7 26.4 16.0 6.5 41.1 23.5 12.8 0.7 1.3 18.8 94.4 27.7 6.5 13.8 9.8 29.6 24.6 1.0 3.1 69.1 24.3 27.2 30.6 9.5 2.6 18.8 11.0 14.9 18.0 4.1 44.1 25.3 0.8 8.2 1.8 8.9 35.4 6.3 10.2 8.2 4.7 6.8 5.5 5.4 5.5 4.2 3.1 1.7 3.5 25.7 7.3 4.6 0.6 3.4 5.6 21.6 23.6 22.3 22.4 21.0 24.5 27.8 24.5 23.3 22.5 24.2 26.0 5.0 12.8 5.6 2.6 4.7 3.2 7.0 5.2 7.4 3.5 6.2 6.6 6.7 11.5 3.4 3.7 4.2 6.1 4.8 9.8 9.8 13.3 3.1 8.3 6.0 6.5 6.0 4.4 1.1 11.7 2.3 5.2 16.3 12.5 5.1 5.2 9.3 10.3 7.8 8.4 1.2 6.8 4.1 6.9 1.7 4.7 5.6 4.6 1.8 1.0 9.4 6.9 5.2 4.0 3.7 9.8 9.3 8.2 12.4 9.5 13.3 4.7 2.6 3.2 6.6 3.1 6.0 0.7 0.5 13.2 2.7 26.8 5.0 9.7 3.3 11.7 AC114490.2 ENSG00000284773 "Novel protein" 1 34974356-34985313 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 6 "Ductal cells: 14.3;Exocrine glandular cells: 7.4;monocytes: 5.2;Pancreatic endocrine cells: 9.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" 1.0 0.5 0.6 0.9 0.6 0.9 1.0 0.9 0.9 0.5 0.3 0.6 0.7 1.6 1.3 0.2 1.0 0.7 0.3 0.5 0.7 0.5 0.4 1.1 1.7 0.5 0.4 1.1 0.3 0.4 0.4 0.5 0.6 0.8 1.0 0.5 0.8 0.5 1.1 1.0 0.8 0.2 1.5 0.4 0.8 0.7 0.7 0.5 0.2 1.1 0.3 0.7 0.2 0.2 0.2 0.3 0.8 1.6 0.1 0.4 1.6 0.2 0.2 0.0 1.0 0.5 0.2 0.5 0.1 0.6 0.1 0.2 0.1 0.9 0.2 0.4 0.3 0.2 1.4 0.7 1.2 1.3 0.5 0.2 0.9 0.8 0.4 1.3 0.1 0.9 0.5 0.3 0.3 0.7 0.3 0.0 0.0 0.6 0.0 0.0 0.4 0.5 0.2 0.5 0.4 0.0 0.1 0.4 0.0 0.5 0.7 0.3 0.3 0.5 0.2 0.9 0.2 0.1 0.3 0.6 0.1 0.1 0.1 0.0 0.3 0.0 0.4 0.1 0.6 0.4 0.1 0.3 0.2 0.2 0.2 0.5 0.1 0.2 0.1 0.0 0.6 0.6 0.9 0.9 0.5 0.7 0.5 0.4 0.5 0.2 0.7 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 14.3 0.0 0.3 0.6 0.7 0.0 0.0 0.0 7.4 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 5.2 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 AC117457.1 ENSG00000275163 "Potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)" 3 178419123-178843300 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "fallopian tube: 5.6;kidney: 1.5" "Group enriched" "Detected in some" 5 "Distal tubular cells: 1.9;Endometrial ciliated cells: 7.1;Proximal tubular cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HSkMC: 1.3" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.6 0.1 0.1 0.2 0.2 1.5 0.1 0.2 0.0 0.7 0.7 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.2 0.2 0.7 0.7 0.3 0.6 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC119676.1 ENSG00000284895 "Novel protein" 1 41585306-41628816 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.8;ASC diff: 5.8;WM-115: 1.7" "Not detected" "Not detected" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.5 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.6 1.8 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.2 1.0 0.3 0.7 0.6 0.3 1.1 0.2 1.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC138696.1 ENSG00000264668 "Novel protein" 8 143247110-143276403 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.7;MOLT-4: 1.2" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: AB_2683082" "unprognostic (2.24e-2)" "unprognostic (2.10e-1)" "unprognostic (3.56e-3)" "unprognostic (1.87e-1)" "unprognostic (8.68e-3)" "unprognostic (1.14e-1)" "unprognostic (1.51e-1)" "unprognostic (9.80e-2)" "unprognostic (4.20e-1)" "unprognostic (3.27e-2)" "unprognostic (1.34e-1)" "unprognostic (1.03e-2)" "unprognostic (2.20e-2)" "unprognostic (3.99e-1)" "unprognostic (2.59e-2)" "unprognostic (4.06e-1)" 0.3 0.3 0.2 0.0 0.3 0.0 0.2 0.1 0.5 0.3 0.0 0.4 0.1 0.6 0.0 0.1 0.7 0.0 0.1 0.3 0.3 0.1 0.1 0.1 0.1 0.2 0.4 0.4 0.6 0.1 0.2 0.0 0.3 0.3 0.0 0.1 0.2 0.2 0.4 0.1 0.3 0.2 0.2 0.1 0.3 0.2 0.3 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.5 0.0 0.0 0.3 1.7 0.1 0.1 0.5 1.1 0.6 0.2 0.0 0.7 0.0 0.3 0.1 0.1 0.2 0.0 0.2 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.2 1.0 0.4 0.0 0.3 0.2 0.3 0.4 0.0 0.0 0.0 0.0 1.2 0.0 1.1 0.1 0.3 0.6 1.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.2 1.1 0.0 0.8 0.2 0.5 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.5 0.3 0.3 0.2 0.4 0.3 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACACA "ACAC, ACC, ACC1" ENSG00000278540 "Acetyl-CoA carboxylase alpha" Q13085 17 37084992-37406836 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 138.1;Excitatory neurons: 230.7;Inhibitory neurons: 197.8;Oligodendrocyte precursor cells: 181.0;Oligodendrocytes: 186.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013715, HPA036650, HPA063018" Approved Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA 110000 "Cluster 30: Non-specific - Translation" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "Nucleoli fibrillar center, Actin filaments" "CAB013715: , HPA036650: AB_2675228, HPA063018: AB_2684922" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.04e-2)" "unprognostic (1.10e-1)" "unprognostic (4.86e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.24e-5)" "unprognostic (8.81e-2)" "unprognostic (6.56e-2)" "unprognostic (2.38e-3)" "unprognostic (3.38e-1)" "unprognostic (2.24e-1)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (4.89e-1)" "unprognostic (4.49e-2)" "unprognostic (2.03e-2)" 16.2 25.4 10.8 3.7 10.8 4.9 22.2 9.0 15.8 11.5 11.3 14.4 5.2 12.1 13.8 25.2 10.8 4.8 7.7 9.5 11.2 13.6 23.3 13.3 2.0 11.1 9.9 11.3 10.5 10.9 19.2 3.8 11.1 26.2 6.4 8.0 14.6 9.6 15.1 15.4 9.6 8.0 8.6 7.3 12.6 16.4 10.3 3.7 8.9 3.6 5.5 19.9 14.6 12.3 34.7 7.0 39.8 42.6 54.7 53.2 13.9 15.2 21.3 15.9 27.5 27.4 5.9 5.0 12.0 24.3 39.4 33.9 7.5 51.1 23.7 13.6 23.2 27.3 15.5 28.0 9.2 14.8 5.3 43.4 29.0 40.2 30.0 18.8 27.5 25.1 66.5 3.2 2.1 27.3 16.3 22.8 30.4 21.5 22.1 24.1 25.3 6.4 36.1 38.5 45.0 17.0 27.8 12.3 12.7 34.8 24.9 16.8 23.8 12.7 20.6 17.3 3.9 8.7 11.5 42.0 11.7 12.3 17.2 0.5 0.8 0.1 0.6 1.3 0.6 0.7 0.7 0.7 1.0 1.1 1.1 0.8 0.3 0.6 0.8 0.7 1.0 0.6 10.8 10.8 9.0 15.8 9.5 11.2 11.1 9.9 11.1 8.6 10.3 12.3 6.8 32.1 51.7 138.1 8.0 11.6 20.8 14.8 22.2 17.2 17.3 11.7 8.0 2.8 16.5 11.0 27.1 16.0 7.0 5.3 9.8 6.7 66.3 19.1 15.6 8.3 9.0 10.7 230.7 8.3 7.6 10.4 15.8 15.9 7.0 19.5 6.4 17.3 5.8 23.5 197.8 7.3 14.2 3.8 4.3 51.2 9.9 6.1 10.6 58.1 4.3 18.2 4.1 181.0 186.9 7.2 6.4 15.8 9.3 22.8 4.8 7.0 10.5 11.8 6.6 10.0 7.8 20.8 20.5 27.8 15.9 16.3 6.4 43.2 10.0 22.0 ACACB "ACC2, ACCB, HACC275" ENSG00000076555 "Acetyl-CoA carboxylase beta" O00763 12 109116595-109268226 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 183.3;skeletal muscle: 173.2" "Cell type enhanced" "Detected in many" "Adipocytes: 128.7;Astrocytes: 136.8;Hepatocytes: 216.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 17.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 17.5" "Cell line enriched" "Detected in many" 18 "ASC diff: 222.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA006554 Enhanced "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "HPA006554: AB_1844495" "unprognostic (2.24e-1)" "unprognostic (4.66e-1)" "unprognostic (3.97e-2)" "unprognostic (4.54e-6)" "unprognostic (2.82e-1)" "unprognostic (1.59e-2)" "unprognostic (8.62e-3)" "unprognostic (5.81e-2)" "unprognostic (2.86e-1)" "unprognostic (1.63e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.63e-2)" "prognostic favorable (1.15e-5)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (1.21e-3)" "unprognostic (2.58e-2)" 183.3 19.8 19.6 3.3 21.7 3.6 100.5 7.6 11.4 12.9 26.9 37.2 8.4 12.0 3.5 10.6 12.1 10.9 35.4 10.1 11.2 12.6 54.3 6.7 3.8 12.7 19.4 14.3 19.2 17.9 11.2 2.5 11.6 11.8 8.2 1.7 12.5 11.7 173.2 9.5 15.5 9.4 6.7 7.8 18.6 4.9 19.1 4.5 18.1 61.5 3.0 23.0 11.5 13.2 0.9 5.7 3.6 6.9 222.6 1.7 2.6 0.9 1.5 1.0 0.6 4.1 1.1 2.9 1.6 1.2 2.4 4.8 3.0 1.5 0.6 3.8 5.3 6.6 6.2 4.3 1.0 5.7 1.6 2.6 1.5 2.3 0.6 1.7 0.5 4.9 0.7 0.3 0.7 1.7 4.1 5.3 3.9 0.4 12.4 2.2 4.8 1.5 1.8 2.0 2.3 5.4 5.9 2.8 3.4 1.5 2.6 5.9 0.4 2.2 1.3 2.5 1.9 8.8 5.3 4.0 5.3 4.5 1.7 4.6 0.4 17.5 1.1 0.1 0.6 2.2 1.0 0.3 0.2 3.0 1.8 0.9 0.7 0.1 0.2 0.3 0.6 0.1 19.6 21.7 7.6 11.4 10.1 11.2 12.7 19.4 11.6 6.7 19.1 13.2 128.7 6.4 1.1 136.8 3.7 2.3 2.6 1.0 3.4 3.1 32.5 5.0 35.3 25.8 1.7 23.9 0.0 0.6 2.4 13.9 1.9 2.1 34.3 3.3 3.4 26.0 10.2 25.7 5.1 4.0 0.5 16.0 18.3 1.3 1.3 20.0 41.4 216.5 1.7 23.5 6.4 9.6 0.0 12.6 2.4 36.4 29.2 3.7 5.4 28.1 1.2 5.2 2.1 29.7 25.8 2.7 7.3 50.4 2.5 0.9 17.9 6.5 2.3 4.1 6.6 29.3 12.0 2.3 3.0 2.5 1.6 0.1 3.5 21.8 11.8 1.1 ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 134.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 194.4;Proximal tubular cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favorable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" 96.6 50.5 15.2 16.1 15.4 3.5 50.1 14.6 15.3 19.8 19.1 23.7 48.6 19.2 30.2 15.4 14.6 15.6 36.3 14.0 16.2 89.2 134.5 20.3 8.8 15.8 15.8 17.4 37.6 22.8 13.1 16.1 14.9 21.9 20.6 12.9 16.6 19.1 25.1 12.0 35.8 22.9 15.3 9.3 28.7 17.6 16.9 13.6 34.5 37.8 7.1 24.4 13.7 14.1 37.5 33.7 25.7 40.7 194.5 104.8 11.6 69.3 169.1 31.2 24.5 36.0 11.4 7.4 21.6 73.1 84.9 5.1 51.3 66.3 62.3 23.8 13.8 54.7 33.4 39.3 97.4 5.1 21.2 91.7 20.1 80.4 56.1 95.6 81.7 28.4 20.0 15.7 89.9 9.9 29.5 26.4 26.9 23.3 35.5 22.8 38.0 7.8 118.9 34.1 3.3 10.5 71.9 2.8 7.6 27.1 16.7 13.5 89.2 112.5 38.2 38.2 18.2 7.8 15.5 14.7 78.7 18.2 10.2 33.2 11.3 3.3 9.2 11.3 8.0 5.6 6.2 6.9 9.3 5.0 8.1 8.2 1.2 6.7 10.0 4.3 3.9 8.4 15.2 15.4 14.6 15.3 14.0 16.2 15.8 15.8 14.9 15.3 16.9 14.1 16.3 3.2 25.7 43.8 6.7 4.5 7.9 11.9 9.1 21.4 17.8 7.4 45.5 38.6 11.7 23.9 22.9 50.8 6.2 26.4 19.6 19.0 8.7 10.0 30.7 18.7 4.9 11.6 24.6 41.0 22.1 29.7 39.3 13.9 2.5 17.1 15.7 194.4 15.1 33.7 46.5 27.7 10.2 14.8 6.7 6.9 23.6 15.6 7.2 20.6 8.6 25.7 8.2 22.1 24.1 19.4 23.7 23.3 7.2 10.1 56.1 183.4 10.7 14.3 19.7 30.5 22.2 9.8 19.4 10.3 5.4 53.5 7.5 22.2 34.6 8.7 ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 177.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.0;Proximal enterocytes: 27.9;Proximal tubular cells: 51.0" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.4;ASC TERT1: 25.9;fHDF/TERT166: 9.2;Hep G2: 10.8;HSkMC: 17.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 29000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" 8.8 8.3 4.1 2.1 4.6 0.1 5.8 4.4 4.5 9.3 16.8 12.9 25.4 9.4 5.8 6.3 10.8 8.2 16.7 4.3 4.5 42.1 177.3 6.2 1.7 5.3 4.8 11.2 4.6 9.6 4.6 3.4 4.4 10.8 8.3 1.8 7.2 9.8 8.2 2.9 21.6 11.2 4.5 1.4 4.0 4.9 4.9 4.0 16.1 17.0 1.2 8.7 6.0 4.1 0.0 0.0 0.2 0.0 16.4 25.9 4.7 3.1 0.2 0.0 0.4 0.8 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 2.3 0.0 0.0 17.4 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.6 4.4 4.5 4.3 4.5 5.3 4.8 4.4 4.5 4.9 4.1 1.9 3.2 5.8 11.1 0.6 0.6 7.6 0.5 5.7 0.3 1.3 3.8 14.3 4.3 0.9 3.7 0.0 0.7 0.0 4.2 15.6 0.3 0.1 0.4 1.3 1.6 3.0 2.7 0.6 1.9 0.4 8.6 2.0 0.2 1.3 8.6 6.1 89.0 5.2 1.7 0.6 5.1 0.0 1.9 0.4 1.8 10.8 1.7 0.0 1.0 0.5 10.8 0.0 0.5 0.0 0.4 0.8 8.6 0.1 0.6 27.9 51.0 0.0 0.8 6.6 7.0 5.2 0.4 0.4 3.0 0.3 0.8 0.3 9.6 4.6 3.8 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in many" "Early spermatids: 355.8;Hepatocytes: 1170.0;Late spermatids: 456.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Cell line enhanced" "Detected in all" "ASC diff: 1124.0;ASC TERT1: 275.2;HSkMC: 609.5;RPTEC TERT1: 358.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 770.4 43.3 32.5 94.8 43.9 337.9 316.7 45.2 70.2 62.1 60.7 34.0 32.4 41.6 78.2 66.0 50.6 36.2 172.7 34.4 39.1 218.7 1319.0 173.7 20.7 63.2 44.4 15.5 49.3 57.0 39.6 30.0 56.2 91.3 16.3 28.4 84.2 30.1 731.8 173.0 34.5 42.8 45.2 132.8 54.2 41.9 63.2 12.2 51.3 442.0 24.7 73.2 57.7 70.8 51.6 15.9 9.7 24.6 1124.0 275.2 8.3 29.1 13.8 16.1 11.2 3.9 14.0 22.2 3.0 32.8 38.4 29.7 43.1 17.8 13.3 107.1 17.7 16.6 13.1 40.5 183.4 41.9 37.2 609.5 140.7 13.6 67.1 27.6 21.1 3.6 7.5 59.4 77.0 26.9 3.1 55.1 2.0 32.5 23.3 8.0 8.6 27.0 358.4 135.9 36.3 35.1 25.4 70.8 86.5 3.9 26.9 39.8 25.1 13.8 16.8 34.5 8.7 24.5 13.5 8.9 45.6 56.3 22.4 16.5 54.7 17.7 3.3 30.9 2.8 3.3 2.3 1.5 13.1 3.4 2.5 2.2 475.2 4.4 23.0 2.4 4.9 20.8 32.5 43.9 45.2 70.2 34.4 39.1 63.2 44.4 56.2 45.2 63.2 70.8 7.5 25.6 121.0 6.5 15.7 21.0 16.0 14.0 5.2 6.6 49.7 10.3 119.1 25.8 33.5 31.3 18.8 10.2 7.1 4.3 93.9 4.6 355.8 9.8 25.0 9.8 0.0 34.1 15.2 12.8 2.2 19.4 36.2 24.6 24.1 1.5 18.2 1170.0 41.8 3.3 22.8 4.7 85.5 140.7 14.6 456.6 19.3 170.1 32.0 6.5 40.5 3.1 1.0 8.5 89.8 8.6 1.6 16.6 8.6 51.3 1.5 111.1 26.8 11.4 13.1 11.1 12.4 10.5 16.7 26.4 41.1 3.4 10.6 1.8 3.2 23.1 ACSM5 FLJ20581 ENSG00000183549 "Acyl-CoA synthetase medium chain family member 5" Q6NUN0 16 20409534-20441336 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 276.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 237.8" "Group enriched" "Detected in some" 7 "liver cancer: 20.5;renal cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 5.3;ASC TERT1: 11.5;HSkMC: 13.8;U-87 MG: 8.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041435 Uncertain Uncertain Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA041435: AB_10961121" "unprognostic (1.01e-1)" "unprognostic (1.61e-3)" "unprognostic (3.73e-2)" "unprognostic (1.98e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-2)" "unprognostic (1.84e-2)" "unprognostic (4.64e-3)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (2.15e-2)" "unprognostic (2.33e-1)" "unprognostic (5.11e-3)" "unprognostic (2.09e-2)" "unprognostic (3.85e-2)" "unprognostic (2.78e-2)" "unprognostic (1.57e-1)" 25.5 2.5 7.1 0.6 5.2 0.6 10.7 4.7 5.0 2.8 3.0 3.7 0.8 1.2 7.1 1.0 1.7 2.3 3.3 5.5 7.9 25.4 276.6 2.1 1.9 6.3 6.8 0.8 0.6 1.0 0.5 1.4 6.8 0.6 1.2 0.5 0.9 0.9 13.9 2.3 1.9 1.0 6.7 4.6 3.4 0.9 8.2 0.7 4.2 1.7 0.7 1.1 2.2 8.2 0.0 0.0 0.1 0.1 5.3 11.5 0.0 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 13.8 0.0 0.8 0.1 0.2 0.0 0.0 0.1 0.5 1.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 8.5 0.1 0.0 0.1 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 7.1 5.2 4.7 5.0 5.5 7.9 6.3 6.8 6.8 6.7 8.2 8.2 0.4 0.0 0.0 1.0 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.5 0.5 0.0 0.3 1.2 0.0 13.5 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 6.1 237.8 3.7 0.0 0.2 0.0 0.0 11.7 1.5 0.8 9.3 3.5 0.0 7.5 1.3 0.9 0.0 1.5 0.1 0.0 0.0 6.0 0.0 0.2 0.0 52.1 0.0 0.1 0.0 11.3 0.3 0.2 0.3 0.1 0.6 0.0 0.7 0.9 0.1 0.2 ACTA2 ACTSA ENSG00000107796 "Actin alpha 2, smooth muscle" P62736 10 88935074-88991339 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 6678.8;seminal vesicle: 5920.3;smooth muscle: 8099.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1007.7;Peritubular cells: 5290.7;Sertoli cells: 3030.6;Smooth muscle cells: 2394.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 390.6;fHDF/TERT166: 641.1;HHSteC: 625.8;HSkMC: 345.1;hTERT-RPE1: 743.4;SuSa: 296.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 101.0" "CAB000002, CAB003761, CAB013531, HPA041264, HPA041271" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "CAB000002: AB_2223500, CAB003761: AB_562031, CAB013531: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.30e-3)" "unprognostic (3.18e-2)" "unprognostic (3.33e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-2)" "unprognostic (1.71e-2)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (1.37e-8)" "unprognostic (1.87e-3)" "unprognostic (2.30e-1)" "unprognostic (7.91e-2)" "unprognostic (2.09e-3)" 1035.2 241.6 54.0 728.1 61.4 3.9 838.4 52.7 121.1 2000.3 61.4 2755.1 248.9 6678.8 1360.1 1509.9 3104.3 906.1 1069.2 53.4 54.6 312.2 161.8 732.8 173.7 59.0 55.9 798.0 91.4 80.6 60.8 771.3 55.3 2642.8 866.4 8.2 414.7 5920.3 202.1 355.7 701.6 8099.9 54.1 452.1 1427.1 263.9 56.1 56.5 312.0 214.0 48.4 3002.5 1367.0 52.9 3.9 19.0 49.3 102.7 198.1 390.6 9.5 109.8 136.8 11.9 45.4 0.0 8.8 7.2 11.5 641.1 8.6 1.4 1.8 25.4 11.3 60.6 11.3 0.4 5.6 119.3 625.8 0.8 3.2 345.1 44.9 73.9 28.5 743.4 11.3 3.0 0.0 7.1 128.8 10.8 1.0 28.3 2.5 0.2 1.2 1.4 0.2 4.6 27.1 5.0 0.7 7.6 10.2 7.9 1.0 296.8 32.4 1.0 27.9 24.0 4.0 30.2 9.3 21.1 1.6 0.6 29.6 10.2 26.1 28.1 12.3 17.5 17.6 8.7 13.8 6.0 14.1 19.8 10.8 1.8 1.5 10.7 11.1 4.0 14.2 0.4 58.7 10.7 54.0 61.4 52.7 121.1 53.4 54.6 59.0 55.9 55.3 54.1 56.1 52.9 65.4 9.6 6.1 5.5 4.4 43.2 23.4 16.5 22.8 1.1 22.7 1007.7 25.1 2.8 5.2 0.0 6.2 16.3 7.3 1.9 1.9 1.8 11.1 11.1 225.4 41.1 0.0 4.0 3.6 0.9 16.8 316.3 10.7 8.2 5.7 448.9 474.0 4.6 37.7 0.0 1.1 2.7 4.1 5.4 67.6 48.8 141.4 12.6 55.2 61.8 4.2 13.4 4.1 1.0 0.3 2.0 3.0 5290.7 3.7 17.5 3.4 9.5 10.9 1.4 3030.6 72.0 2394.6 4.0 13.8 11.1 40.5 23.7 16.5 36.0 5.7 10.4 ACTRT3 ARPM1 ENSG00000184378 "Actin related protein T3" Q9BYD9 3 169766921-169769561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 47.5" "Cell type enriched" "Detected in many" 6 "Early spermatids: 1021.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 18.1;HSkMC: 11.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA035817, HPA035818" Approved Approved Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA035817: AB_10671938, HPA035818: AB_2674801" "unprognostic (2.35e-1)" "unprognostic (9.39e-2)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.11e-4)" "unprognostic (1.89e-2)" "unprognostic (1.75e-1)" "unprognostic (3.29e-1)" "unprognostic (1.24e-1)" "unprognostic (7.31e-4)" "unprognostic (2.64e-1)" "unprognostic (9.16e-2)" "unprognostic (4.41e-2)" "unprognostic (8.03e-2)" "unprognostic (8.49e-2)" "unprognostic (1.63e-1)" "unprognostic (8.25e-3)" "unprognostic (2.22e-1)" 1.6 0.9 1.7 0.7 2.1 0.4 1.1 2.6 4.5 1.4 2.0 0.9 1.1 1.1 0.8 1.0 2.0 0.9 1.2 2.2 2.0 2.4 2.7 1.1 0.8 2.1 3.5 1.6 0.6 1.2 1.3 1.0 2.2 1.2 0.8 0.8 0.6 1.9 0.7 0.4 0.8 1.6 1.8 0.4 1.2 47.5 2.5 0.8 1.5 0.7 0.9 1.7 0.7 2.6 4.0 2.5 0.2 1.1 18.1 5.5 0.0 4.7 3.0 3.1 2.6 0.0 5.2 0.0 6.5 5.9 2.0 2.5 1.5 2.5 3.3 2.9 1.7 9.3 1.9 0.5 3.0 1.1 0.9 11.8 0.6 3.8 0.7 2.0 5.8 0.9 0.0 0.0 5.7 2.0 0.2 0.1 4.5 3.5 5.3 0.6 0.0 0.1 3.3 1.0 3.1 2.1 5.9 1.4 0.1 0.6 2.5 4.1 2.4 0.0 0.0 2.5 0.0 0.4 0.2 0.2 1.1 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.9 0.3 0.0 0.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 1.7 2.1 2.6 4.5 2.2 2.0 2.1 3.5 2.2 1.8 2.5 2.6 0.9 0.0 1.5 0.3 0.1 0.4 1.3 1.6 1.2 1.6 0.4 0.4 0.7 0.0 2.0 0.0 2.1 1.7 0.1 0.2 1.9 2.3 1021.8 1.1 0.6 1.8 0.0 0.4 0.2 2.1 1.3 1.7 0.5 0.9 1.3 1.3 2.2 2.1 1.5 3.3 0.2 1.3 0.0 0.8 0.7 161.0 9.6 2.2 1.8 0.0 0.0 1.5 0.0 0.0 0.0 2.1 0.1 5.7 0.2 0.7 0.5 2.8 2.1 1.3 13.1 1.1 1.4 24.6 4.6 1.2 0.0 0.8 1.3 3.8 1.2 0.4 ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157628864 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 31.3;brain: 10.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 26.2;Leydig cells: 31.7;Oligodendrocytes: 55.8;Proximal enterocytes: 17.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 10.9;HDLM-2: 5.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 29.7" "HPA007982, HPA011933" Uncertain "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" 31.3 2.5 3.2 0.6 6.3 0.1 6.2 1.3 3.5 0.5 0.0 4.1 4.1 0.1 0.3 0.2 0.1 0.3 0.4 6.4 10.2 0.4 2.2 0.2 0.5 1.4 1.9 3.6 1.5 0.0 2.2 0.1 1.3 0.2 3.0 0.4 0.8 0.3 0.8 0.3 3.4 0.2 0.9 0.1 2.1 0.4 6.6 0.2 0.2 0.3 0.3 0.1 0.2 3.8 1.5 0.0 0.0 0.1 10.9 0.3 0.2 0.3 0.3 0.1 0.3 1.7 0.2 0.0 0.1 0.9 0.7 0.0 0.1 0.0 0.2 5.1 0.7 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 1.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.2 0.0 0.2 0.0 0.6 0.2 0.0 0.1 0.6 1.9 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.4 0.2 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 3.2 6.3 1.3 3.5 6.4 10.2 1.4 1.9 1.3 0.9 6.6 3.8 0.5 0.0 1.1 14.7 1.4 0.6 0.7 0.9 1.8 0.8 0.9 0.3 1.9 0.0 0.9 0.0 0.0 0.2 0.3 14.3 0.0 0.2 1.9 0.4 4.9 0.7 7.8 0.0 26.2 0.2 0.8 0.9 2.6 0.5 0.0 0.4 1.1 5.9 0.1 0.0 11.0 9.2 2.0 0.0 1.3 2.9 31.7 0.1 3.6 3.7 4.3 1.8 0.0 3.5 55.8 0.4 7.6 9.1 2.9 1.8 17.7 1.1 0.2 0.3 0.0 0.6 0.8 0.4 2.4 0.7 1.4 0.3 2.5 0.4 13.5 0.5 ACYP2 ENSG00000170634 "Acylphosphatase 2" P14621 2 53970838-54305300 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.4;tongue: 163.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 162.6;Excitatory neurons: 158.8;Oligodendrocytes: 180.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035301 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA035301: AB_10670291" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (3.40e-1)" "unprognostic (2.16e-1)" "unprognostic (6.90e-3)" "unprognostic (6.21e-2)" "unprognostic (2.03e-3)" "unprognostic (3.17e-1)" "unprognostic (5.22e-2)" "unprognostic (7.83e-3)" "unprognostic (3.64e-3)" "unprognostic (1.16e-1)" "unprognostic (6.66e-2)" "unprognostic (2.13e-1)" "unprognostic (1.97e-1)" "unprognostic (3.24e-1)" "unprognostic (2.24e-2)" 19.5 42.8 64.9 5.4 72.9 7.1 15.7 74.8 85.4 10.6 61.5 14.3 7.4 11.5 12.8 10.4 11.6 8.5 63.4 63.9 72.8 14.5 28.0 10.6 10.9 69.5 68.8 9.3 12.7 13.6 26.2 6.5 70.3 14.4 5.3 24.1 15.2 9.2 207.4 9.9 9.0 7.9 70.4 12.7 12.9 10.2 70.4 10.7 12.6 163.2 8.4 14.0 10.7 76.9 11.7 5.9 6.0 4.4 23.7 17.3 3.7 11.5 9.7 8.3 7.3 1.5 7.1 21.5 33.0 12.6 7.8 8.5 3.3 10.8 7.4 14.4 13.1 13.4 6.3 16.3 8.5 12.7 6.3 13.6 19.3 5.6 9.5 15.2 3.9 9.8 5.5 11.5 17.9 7.6 7.5 17.0 5.9 8.4 6.7 5.4 4.7 12.2 18.8 10.6 17.6 10.0 17.4 10.0 5.7 1.9 3.4 13.2 10.9 11.5 10.6 3.5 11.1 21.4 12.5 10.2 16.3 24.3 12.4 41.2 14.0 26.1 16.9 13.0 15.4 29.0 16.6 16.1 20.3 26.9 20.1 16.4 11.5 18.6 13.5 33.4 16.3 11.3 64.9 72.9 74.8 85.4 63.9 72.8 69.5 68.8 70.3 70.4 70.4 76.9 21.7 16.0 17.9 84.9 30.6 20.5 41.9 52.8 18.8 15.5 49.7 65.7 162.6 34.3 32.0 18.4 10.4 13.6 27.9 24.5 62.6 24.3 86.8 29.5 23.6 23.1 30.6 14.5 158.8 38.1 6.1 21.0 26.0 19.5 19.7 17.6 30.7 74.2 31.9 28.6 134.1 21.9 36.7 40.0 28.5 64.7 13.4 25.4 23.2 59.0 26.1 90.1 24.7 67.8 180.1 29.9 18.8 30.9 36.4 27.4 29.1 55.6 32.2 31.6 52.6 30.8 30.0 22.9 9.8 28.9 21.3 10.3 22.7 29.7 18.6 45.0 ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 40.8;Fibroblasts: 45.2;Leydig cells: 22.7;Microglial cells: 18.7;Smooth muscle cells: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 82.4;ASC TERT1: 104.9;BJ: 38.5;BJ hTERT+: 64.7;fHDF/TERT166: 38.9;U-2197: 50.9" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" 53.3 3.8 7.8 10.5 8.5 0.1 47.4 5.8 12.3 280.4 8.4 157.2 11.0 151.8 19.0 31.6 106.9 32.8 26.7 6.7 9.3 3.9 2.0 18.0 6.2 16.0 8.0 58.7 6.0 0.5 6.9 12.7 16.4 87.0 12.1 1.0 19.6 57.5 9.1 22.0 43.4 53.0 5.9 8.3 44.8 22.5 6.9 0.9 18.4 14.1 2.2 125.4 159.0 6.2 0.0 0.0 0.2 0.0 82.4 104.9 0.2 38.5 64.7 11.2 21.3 0.1 0.0 0.0 0.2 38.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 13.0 0.0 0.0 18.2 0.0 4.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 2.8 0.2 2.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 0.2 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 8.5 5.8 12.3 6.7 9.3 16.0 8.0 16.4 5.9 6.9 6.2 3.9 0.0 0.0 7.2 0.1 5.5 0.1 0.0 0.6 0.0 0.3 0.3 3.3 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.5 1.8 40.8 2.4 0.0 0.0 1.3 0.0 0.1 45.2 2.6 1.2 0.0 3.1 1.8 0.0 0.5 0.0 11.4 0.0 0.0 0.3 8.8 0.8 22.7 0.8 3.6 18.7 0.0 2.2 0.0 8.0 0.1 0.0 0.0 10.1 0.0 0.2 0.0 0.9 0.0 0.1 6.6 6.8 17.1 0.7 0.5 0.3 3.1 0.5 0.7 0.0 0.0 0.1 ADAMTS15 ENSG00000166106 "ADAM metallopeptidase with thrombospondin type 1 motif 15" Q8TE58 11 130448974-130476641 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 26.4" "Cell type enhanced" "Detected in some" "Adipocytes: 8.6;Cardiomyocytes: 11.0;Endometrial stromal cells: 15.6;Fibroblasts: 9.6;Gastric mucus-secreting cells: 8.2;Glandular and luminal cells: 7.5;Granulosa cells: 6.8;Skeletal myocytes: 6.9" "Cancer enhanced" "Detected in many" "breast cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 72.0;ASC TERT1: 43.0;EFO-21: 36.6;hTERT-RPE1: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA042867 Uncertain Approved Cytosol "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA042867: AB_10794535" "unprognostic (7.64e-2)" "unprognostic (1.49e-3)" "unprognostic (7.15e-2)" "unprognostic (1.34e-3)" "unprognostic (1.07e-3)" "unprognostic (7.07e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (9.72e-4)" "unprognostic (6.18e-2)" "unprognostic (4.37e-2)" "unprognostic (2.56e-1)" "unprognostic (7.40e-2)" "unprognostic (1.29e-2)" "unprognostic (5.95e-3)" "unprognostic (6.68e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.63e-5)" 26.4 1.2 0.4 1.7 0.5 0.0 15.3 0.4 0.8 3.4 1.7 3.2 0.5 4.3 1.3 3.7 9.8 2.3 14.5 0.4 0.9 11.0 0.4 7.2 1.1 4.4 0.6 2.7 1.4 0.4 1.3 16.9 1.5 1.9 1.9 0.2 1.3 1.1 1.8 5.0 3.6 4.6 1.0 2.3 5.5 0.9 1.2 1.1 7.0 1.0 0.3 8.8 2.6 1.0 0.0 2.6 1.6 0.8 72.0 43.0 0.0 2.7 5.2 1.0 0.2 0.5 1.2 0.0 36.6 0.2 2.6 7.0 0.6 0.7 0.2 0.0 1.7 0.0 3.3 0.0 0.7 0.0 0.0 14.1 0.0 0.6 0.1 19.5 0.0 0.3 0.0 0.0 0.0 0.1 0.1 8.1 1.3 0.0 5.7 0.0 4.1 0.0 0.1 0.1 0.6 0.0 12.1 0.0 0.0 5.2 3.9 0.0 0.0 0.6 8.5 7.0 3.5 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.8 0.4 0.9 4.4 0.6 1.5 1.0 1.2 1.0 8.6 0.0 0.0 0.3 0.2 0.5 0.1 3.5 0.0 1.3 5.6 2.7 11.0 0.0 0.5 1.8 0.0 0.6 0.0 1.0 0.0 0.0 0.0 4.4 15.6 1.7 0.0 0.0 0.4 0.8 0.6 9.6 8.2 7.5 0.0 6.8 0.4 0.1 0.9 0.0 1.6 0.5 2.0 0.0 0.3 0.0 5.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.9 0.7 0.0 0.0 0.1 1.0 0.5 0.0 0.0 6.9 3.6 0.2 0.3 0.0 0.3 0.8 0.1 0.0 1.8 0.1 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 32.2;Excitatory neurons: 17.9;Fibroblasts: 30.7;Hepatic stellate cells: 17.2;Kupffer cells: 71.4;Sertoli cells: 26.3;Smooth muscle cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 35.8;BJ: 31.4;fHDF/TERT166: 39.3;HHSteC: 115.5;HSkMC: 94.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 36.9 10.9 0.8 2.4 4.2 0.3 22.7 0.9 3.5 20.6 0.9 10.5 1.4 21.7 0.5 5.5 15.5 6.1 22.3 0.5 0.9 7.5 15.8 29.6 1.8 4.5 3.3 12.1 5.8 0.4 15.1 9.7 4.2 9.0 1.4 0.2 5.3 1.8 2.9 9.4 11.6 9.1 0.2 38.4 9.3 3.9 2.5 0.4 6.8 0.8 0.6 15.0 16.7 2.2 0.0 0.0 0.1 0.7 36.0 35.8 0.0 31.4 5.4 11.5 12.4 0.1 0.0 0.0 0.2 39.3 0.7 0.1 1.8 0.0 5.1 0.0 1.5 0.0 0.1 2.3 115.5 0.0 0.0 94.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.9 1.2 0.1 0.0 0.4 1.9 0.0 10.7 0.0 19.1 3.0 24.5 0.0 0.3 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.8 4.2 0.9 3.5 0.5 0.9 4.5 3.3 4.2 0.2 2.5 2.2 3.3 0.0 1.1 1.6 0.1 2.2 0.4 0.0 2.2 0.3 0.2 5.2 1.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.3 0.9 32.2 1.4 0.0 0.0 17.9 0.0 0.3 30.7 0.0 0.8 1.3 6.5 17.2 0.5 5.1 0.0 8.5 0.0 0.0 71.4 4.4 3.4 5.0 10.4 0.0 4.7 0.3 0.1 0.0 3.0 2.4 0.5 0.0 12.8 0.1 0.4 0.0 0.2 0.0 0.0 26.3 4.7 20.4 2.1 4.8 0.2 2.7 0.0 0.4 0.6 0.0 0.1 ADAMTS5 "ADAMTS11, ADMP-2" ENSG00000154736 "ADAM metallopeptidase with thrombospondin type 1 motif 5" Q9UNA0 21 26917922-26967088 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 26.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 38.2;Endometrial stromal cells: 72.1;Fibroblasts: 88.6;Leydig cells: 62.7;Skeletal myocytes: 110.2;Smooth muscle cells: 44.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 31.6;ASC TERT1: 13.9;fHDF/TERT166: 11.9;RH-30: 33.1;U-87 MG: 13.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA005661, CAB025996, HPA030906, HPA030908" Approved Supported Nucleoplasm "Secreted to extracellular matrix" NA NA 28000 "Cluster 5: Breast - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB025996: , HPA005661: AB_1078101, HPA030906: AB_2673654, HPA030908: AB_2673655" "unprognostic (1.97e-1)" "unprognostic (2.88e-3)" "unprognostic (2.69e-2)" "unprognostic (4.01e-2)" "unprognostic (4.67e-1)" "unprognostic (2.10e-2)" "unprognostic (4.38e-8)" "unprognostic (1.11e-3)" "unprognostic (7.66e-2)" "unprognostic (6.17e-2)" "unprognostic (8.13e-2)" "unprognostic (7.76e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (6.69e-3)" "unprognostic (3.01e-1)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.15e-1)" 17.5 0.8 0.3 1.0 0.6 0.0 10.8 3.3 0.3 8.8 2.6 2.7 0.8 12.5 2.4 1.6 4.2 1.6 3.3 0.5 0.9 2.5 1.4 1.0 0.6 1.4 0.9 16.6 0.4 1.5 0.4 26.2 0.9 3.0 1.3 0.6 2.0 1.8 2.0 4.2 3.4 7.5 1.5 7.7 2.2 0.8 0.4 0.3 6.8 3.7 0.1 4.2 3.6 1.2 0.0 0.0 0.0 0.0 31.6 13.9 0.0 1.7 0.2 1.4 0.6 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 2.3 0.0 1.3 0.0 0.3 0.0 3.5 0.1 0.0 8.0 0.0 1.1 0.2 0.2 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 33.1 0.0 3.4 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 8.3 0.4 1.9 0.9 0.0 0.0 0.0 13.0 0.1 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 3.3 0.3 0.5 0.9 1.4 0.9 0.9 1.5 0.4 1.2 24.3 0.0 0.5 0.3 0.1 2.9 0.2 0.4 0.0 9.8 1.5 38.2 2.7 0.0 0.6 3.7 0.0 1.1 0.3 0.0 0.0 0.0 6.4 2.0 72.1 10.6 1.8 0.0 0.5 0.2 1.6 88.6 0.0 1.3 0.0 3.0 3.3 0.0 1.9 0.0 11.6 0.0 0.0 0.0 4.6 1.0 62.7 1.4 3.6 3.7 4.0 0.1 0.0 12.5 0.2 0.0 0.0 9.1 0.0 0.3 0.0 2.2 0.0 0.2 13.1 110.2 44.9 0.3 0.9 0.4 3.0 2.7 0.8 20.0 0.0 0.1 ADCY3 AC3 ENSG00000138031 "Adenylate cyclase 3" O60266 2 24819169-24920237 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis, Olfaction, Sensory transduction" "Calmodulin-binding, Lyase" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 58.4;Sertoli cells: 111.7;Smooth muscle cells: 62.8;Theca cells: 92.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010223 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB010223: AB_630839" "unprognostic (3.05e-1)" "unprognostic (1.10e-1)" "unprognostic (4.91e-2)" "unprognostic (1.39e-3)" "unprognostic (5.01e-2)" "unprognostic (7.66e-2)" "unprognostic (1.28e-1)" "unprognostic (6.06e-2)" "unprognostic (8.43e-2)" "unprognostic (6.89e-2)" "unprognostic (8.22e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (1.32e-9)" "unprognostic (3.74e-2)" "unprognostic (5.56e-2)" "unprognostic (1.11e-1)" "unprognostic (8.55e-3)" 94.4 17.3 43.5 17.3 55.1 17.7 74.6 36.7 50.1 66.7 28.4 27.5 10.9 56.4 20.5 30.4 62.1 23.0 36.6 43.3 43.4 25.9 6.6 42.5 18.9 41.6 43.8 71.9 15.7 17.0 41.7 83.6 41.1 40.6 15.8 4.2 21.6 33.0 15.2 38.4 34.4 35.3 36.9 30.4 25.0 9.8 50.6 11.4 36.8 20.4 18.1 36.4 48.9 44.9 76.5 40.4 17.2 28.3 84.5 75.4 29.6 32.3 65.9 37.1 37.8 38.6 25.1 26.0 6.2 53.2 51.0 54.5 43.1 54.5 24.0 58.4 55.8 43.0 40.0 1.7 64.0 24.0 24.6 55.7 47.5 36.6 50.8 23.6 33.8 27.9 15.5 49.2 19.3 43.6 17.9 2.1 14.9 39.9 24.4 38.8 75.3 59.5 15.5 38.7 31.6 19.1 45.8 54.2 30.2 13.0 13.5 22.5 33.5 59.7 34.2 39.1 54.1 42.4 101.6 113.6 18.7 39.2 31.4 2.6 1.5 0.0 0.4 1.6 0.3 5.5 0.9 0.5 9.5 6.0 0.7 0.5 0.0 1.2 0.4 9.0 3.4 1.0 43.5 55.1 36.7 50.1 43.3 43.4 41.6 43.8 41.1 36.9 50.6 44.9 14.6 0.0 1.8 17.0 8.2 11.0 4.2 4.1 5.2 3.0 18.6 8.0 2.8 0.0 1.3 1.8 0.0 1.0 5.2 5.0 0.0 0.9 0.3 1.9 42.2 10.6 1.2 5.2 40.1 0.0 2.1 25.5 2.0 2.2 18.4 3.7 5.0 0.3 12.6 0.0 36.8 6.0 2.0 5.4 6.9 3.9 58.4 10.1 7.2 21.5 4.0 1.6 0.0 15.1 33.2 1.0 5.8 29.3 4.9 11.2 8.3 0.2 1.1 2.2 111.7 6.5 62.8 0.4 2.4 4.4 11.8 1.2 7.2 92.9 12.1 3.9 ADD3 ADDL ENSG00000148700 "Adducin 3" Q9UEY8 10 109996368-110135565 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 449.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.2;ASC TERT1: 292.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009797, HPA035696" Supported Supported "Plasma membrane" NA NA 260000 "Cluster 2: Granulocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB009797: AB_2223583, HPA035696: AB_2674740" "unprognostic (2.66e-1)" "unprognostic (2.63e-2)" "unprognostic (1.46e-3)" "unprognostic (1.64e-1)" "unprognostic (2.65e-2)" "unprognostic (1.75e-2)" "unprognostic (1.57e-3)" "unprognostic (6.42e-2)" "unprognostic (5.73e-2)" "unprognostic (2.37e-2)" "unprognostic (7.58e-2)" "unprognostic (9.12e-2)" "unprognostic (2.34e-3)" "unprognostic (1.36e-1)" "unprognostic (4.03e-1)" "unprognostic (3.68e-2)" "unprognostic (5.92e-2)" 57.7 21.7 105.6 38.8 97.2 37.5 89.4 88.6 129.3 57.6 65.9 58.2 71.9 24.9 62.4 39.0 47.6 72.0 59.9 113.3 108.1 102.7 27.8 38.4 70.9 107.3 94.8 46.4 67.9 18.8 25.3 36.6 102.0 32.7 66.0 99.4 59.1 31.8 9.6 33.6 85.4 23.9 105.2 40.0 63.7 51.5 95.6 87.4 87.7 25.6 65.4 42.3 40.1 122.4 29.2 6.0 41.7 19.8 313.2 292.1 17.7 41.2 110.9 25.4 49.9 60.3 90.6 89.9 45.2 63.9 26.4 10.0 37.3 27.1 39.5 9.0 46.5 8.8 28.5 45.9 35.5 30.5 66.0 142.5 12.9 63.3 2.6 96.4 37.8 109.9 23.5 48.7 46.7 0.8 32.3 31.0 25.8 69.2 15.3 27.7 58.2 4.8 65.7 14.2 6.1 67.9 27.6 8.9 66.5 62.2 10.7 11.4 9.5 16.0 42.0 33.5 9.1 68.9 31.5 82.7 47.8 16.2 27.7 139.5 29.6 98.0 68.8 26.5 55.7 51.4 72.9 59.1 24.8 42.9 83.2 67.6 47.1 73.4 32.6 16.3 73.3 94.9 105.6 97.2 88.6 129.3 113.3 108.1 107.3 94.8 102.0 105.2 95.6 122.4 67.3 22.4 52.9 449.2 110.6 55.7 35.9 77.4 38.7 26.8 56.0 34.4 128.2 74.4 85.5 36.8 60.5 55.6 112.7 125.2 60.7 27.2 51.4 70.3 76.0 77.7 102.4 32.6 83.4 61.1 12.1 182.4 100.9 56.0 26.0 18.8 126.7 12.2 25.7 116.1 141.1 71.6 48.8 88.5 41.1 25.7 226.5 66.3 58.7 70.3 65.3 339.0 151.4 236.8 279.6 59.8 167.1 251.3 68.4 38.4 135.2 162.2 151.9 121.7 65.7 27.6 36.2 122.7 62.1 53.2 50.6 22.3 111.5 30.9 166.7 98.6 ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 30.6;Endometrial stromal cells: 49.4;Fibroblasts: 36.4;Hepatic stellate cells: 31.4;Leydig cells: 56.5;Microglial cells: 24.4;Muller glia cells: 25.0;Peritubular cells: 41.8;Sertoli cells: 46.0;Smooth muscle cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 83.6;ASC TERT1: 64.8;BJ hTERT+: 75.2;fHDF/TERT166: 77.6;HSkMC: 39.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012393 Uncertain NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" 29.1 4.8 10.0 12.2 8.6 2.0 26.4 8.7 10.1 59.8 5.9 24.1 7.7 45.1 18.2 24.8 43.8 26.2 17.6 9.8 6.5 9.6 4.3 16.2 7.7 7.7 8.3 35.9 5.5 2.2 10.0 48.7 7.8 44.4 8.2 6.7 9.0 54.9 6.6 13.1 12.8 27.8 7.0 11.9 12.3 3.5 11.2 5.2 11.3 8.3 5.6 39.6 32.0 6.6 0.2 2.3 0.3 4.7 83.6 64.8 0.6 38.5 75.2 4.6 12.4 0.5 0.2 0.0 6.9 77.6 3.1 0.9 3.5 0.2 1.5 1.6 1.8 0.2 2.2 0.2 38.1 0.0 0.0 39.4 0.4 3.4 0.8 3.3 22.3 3.0 0.2 0.7 1.2 1.2 0.1 8.0 3.5 0.0 0.6 6.5 4.2 0.4 0.0 0.1 0.3 18.1 1.0 0.2 5.7 17.7 0.2 16.9 18.2 7.6 9.6 11.2 3.5 6.2 0.5 0.1 1.0 20.3 8.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 8.6 8.7 10.1 9.8 6.5 7.7 8.3 7.8 7.0 11.2 6.6 30.6 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 1.0 1.0 1.1 1.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 1.9 0.1 0.2 1.5 49.4 17.8 0.0 0.0 7.8 1.6 0.6 36.4 0.0 2.2 0.0 0.1 31.4 0.1 2.1 0.0 7.8 0.2 0.0 1.6 0.0 3.1 56.5 1.5 0.0 24.4 1.0 25.0 1.0 3.0 0.8 0.3 0.1 41.8 0.1 0.3 0.0 0.0 0.0 0.7 46.0 5.5 36.0 0.3 0.8 0.5 0.0 2.3 0.4 2.6 0.3 0.2 ADH1A ADH1 ENSG00000187758 "Alcohol dehydrogenase 1A (class I), alpha polypeptide" P07327 4 99276369-99291003 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 306 "liver: 2739.1" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 200.9" "Cancer enriched" "Detected in some" 251 "liver cancer: 165.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 8.2" "CAB009562, HPA047814, HPA060902" Enhanced Approved "Plasma membrane,Cytosol" NA NA 38000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "CAB009562: AB_2257984, HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.89e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "prognostic favorable (2.38e-4)" "unprognostic (2.78e-3)" "unprognostic (4.25e-1)" "unprognostic (4.79e-3)" "unprognostic (6.21e-2)" "unprognostic (9.36e-2)" "unprognostic (3.25e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-2)" 7.2 1.6 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.3 8.9 0.3 0.5 0.1 0.5 6.6 0.3 0.0 0.0 0.7 2739.1 0.8 0.0 0.1 0.1 0.1 1.1 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 1.8 0.0 0.1 0.3 0.4 0.3 0.0 0.0 0.1 1.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 15.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.1 0.3 0.0 10.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 8.6 200.9 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1501.5;liver: 5858.7" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 4153.7" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 6574.3" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" NA NA 39000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" 1501.5 140.2 2.2 36.4 3.4 0.1 924.6 1.9 9.0 41.0 13.5 202.2 38.5 161.4 74.8 105.8 385.0 145.1 215.3 2.0 1.9 66.7 5858.7 373.2 25.8 4.7 2.2 117.7 49.1 7.8 24.2 6.8 3.2 26.7 114.7 0.1 67.9 26.7 66.6 159.2 237.1 73.4 4.4 72.7 141.1 2.8 2.2 19.8 94.5 228.2 16.0 287.9 118.7 2.4 0.0 0.0 0.0 0.0 6574.3 956.7 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.7 0.1 1.1 0.0 0.0 0.5 1.4 0.0 0.1 0.0 1.1 0.1 0.0 26.9 3.0 0.0 216.8 0.1 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.1 3.2 0.1 0.0 0.0 0.1 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.2 0.3 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.4 1.9 9.0 2.0 1.9 4.7 2.2 3.2 4.4 2.2 2.4 29.0 0.0 3.4 0.0 8.1 22.3 0.5 0.1 6.8 0.1 1.1 2.5 12.2 110.1 2.3 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.6 0.1 0.9 14.7 0.0 115.0 0.0 0.0 0.1 633.1 11.2 0.0 1.3 0.0 96.8 4153.7 0.1 0.0 0.0 0.0 0.0 98.8 25.4 0.6 55.3 3.5 28.4 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.7 0.0 0.1 0.2 0.1 6.6 15.0 47.9 0.0 0.1 10.4 13.1 0.1 8.9 0.1 0.0 0.2 ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336497-99352746 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "intestine: 598.1;liver: 2062.2;stomach 1: 570.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 699.4;Gastric mucus-secreting cells: 611.2;Hepatocytes: 440.6;Undifferentiated cells: 420.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 238.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.1;ASC TERT1: 3.6;HSkMC: 11.9;RPMI-8226: 2.1" "HPA047814, HPA060902" Supported Supported "Plasma membrane,Cytosol" NA NA 31000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (3.98e-2)" "unprognostic (9.88e-3)" "unprognostic (7.04e-2)" "unprognostic (1.90e-1)" "unprognostic (5.14e-1)" "unprognostic (1.57e-1)" "prognostic favorable (4.55e-4)" "prognostic favorable (2.99e-4)" "unprognostic (8.25e-2)" "unprognostic (8.89e-3)" "unprognostic (7.95e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (9.37e-2)" 22.9 0.8 0.1 29.8 0.1 0.0 19.2 0.1 0.1 4.7 0.0 329.5 598.1 5.1 7.2 5.1 5.8 51.6 5.9 0.1 0.0 19.6 2062.2 2.9 0.6 0.1 0.1 4.0 16.7 0.1 1.6 0.1 0.1 9.4 191.9 0.0 19.3 6.2 23.9 0.7 190.7 16.3 0.1 0.7 570.6 0.8 0.1 0.5 2.9 31.1 0.5 5.9 3.6 0.2 0.0 2.1 0.0 0.0 1.4 3.6 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.2 1.1 0.3 11.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.8 0.2 0.0 0.1 0.1 0.8 2.1 0.8 0.0 0.3 1.1 0.5 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.3 0.1 0.1 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 2.1 3.2 7.3 0.7 1.3 0.0 4.0 0.0 25.0 0.0 0.1 0.3 1.0 64.3 24.8 29.5 0.0 0.0 0.1 108.4 0.0 159.5 2.3 1.3 0.8 1.2 21.6 29.5 0.3 699.4 0.0 21.1 611.2 1.3 0.0 0.0 13.2 440.6 0.0 0.0 0.2 86.3 0.0 13.2 0.0 1.0 10.5 0.8 0.0 0.0 2.0 0.0 0.0 0.5 0.1 66.3 120.8 0.0 0.6 3.1 59.4 1.4 43.7 0.0 0.0 1.3 2.0 0.0 0.7 10.6 0.0 0.0 1.8 1.6 420.5 3.6 ADH5 "ADH-3, ADHX, FDH, GSNOR" ENSG00000197894 "Alcohol dehydrogenase 5 (class III), chi polypeptide" P11766 4 99070978-99088801 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044578, HPA061919" Approved NA NA 5300000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "HPA044578: AB_2679002, HPA061919: AB_2684638" "unprognostic (1.05e-1)" "unprognostic (1.63e-2)" "unprognostic (1.14e-3)" "prognostic favorable (9.90e-5)" "unprognostic (2.63e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (1.22e-1)" "prognostic favorable (4.58e-10)" "unprognostic (1.79e-3)" "unprognostic (9.05e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" 141.5 71.3 48.3 52.5 48.2 28.5 111.9 48.0 56.0 92.7 55.8 158.8 94.2 134.8 142.2 114.4 95.9 69.3 124.3 45.9 54.6 175.4 264.1 73.5 51.3 47.6 48.5 118.4 49.4 50.1 41.4 60.9 47.9 116.2 100.8 36.0 65.4 124.6 80.9 54.8 94.3 118.0 49.7 51.6 91.3 52.2 48.6 83.3 79.2 75.8 55.5 158.9 73.9 51.4 84.0 66.9 194.8 110.0 344.7 316.0 116.6 136.6 237.6 143.8 125.2 77.1 96.7 96.5 77.5 197.8 92.8 69.8 135.0 188.7 137.7 69.9 56.6 67.1 83.3 306.7 332.2 118.4 51.9 287.3 143.1 108.3 84.7 151.0 112.8 99.8 125.8 53.3 192.3 94.9 160.4 105.4 156.7 20.6 79.8 115.4 108.9 50.9 230.2 96.0 74.0 97.0 82.7 96.6 155.9 141.8 78.2 82.2 85.4 130.5 82.9 86.4 95.2 55.9 74.4 135.4 134.2 77.4 135.7 21.8 21.2 35.8 32.6 18.9 29.5 26.0 35.3 30.4 23.8 26.2 34.0 31.9 3.0 51.3 14.1 20.5 49.5 32.8 48.3 48.2 48.0 56.0 45.9 54.6 47.6 48.5 47.9 49.7 48.6 51.4 69.0 105.8 78.2 22.9 48.1 39.6 85.9 257.5 109.3 31.8 32.1 74.3 127.4 78.6 94.3 55.2 10.4 290.1 51.8 80.4 197.6 94.8 24.0 146.9 159.1 56.3 79.7 45.8 14.3 83.8 277.2 131.2 37.8 113.0 26.6 83.3 47.2 188.0 118.1 38.7 12.0 101.8 87.5 48.6 27.1 22.0 187.4 43.4 53.4 15.9 63.2 152.4 77.2 27.6 13.9 78.4 86.0 255.1 41.5 34.9 95.2 316.0 56.8 46.5 111.7 55.6 127.7 30.5 48.5 74.9 23.0 83.0 58.5 147.0 104.8 68.1 ADI1 "APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL" ENSG00000182551 "Acireductone dioxygenase 1" Q9BV57 2 3497366-3519531 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 590.7" "Cell type enhanced" "Detected in all" "Distal tubular cells: 888.3;Hepatocytes: 1234.6;Proximal tubular cells: 1546.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035403, HPA035404" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus" "HPA035403: AB_10603576, HPA035404: AB_2674611" "unprognostic (2.19e-2)" "unprognostic (1.68e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "unprognostic (3.65e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-3)" "unprognostic (4.23e-3)" "unprognostic (2.36e-3)" "unprognostic (4.00e-3)" "unprognostic (2.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.90e-2)" "unprognostic (1.56e-1)" "unprognostic (9.94e-2)" "unprognostic (6.76e-2)" "unprognostic (8.74e-2)" 55.1 76.9 31.1 28.0 32.6 31.7 50.4 31.7 42.1 54.2 43.3 58.3 105.2 45.6 43.3 48.2 45.2 66.7 146.4 32.0 31.0 200.2 590.7 44.6 30.1 33.0 32.2 50.0 34.9 49.6 33.5 41.3 33.6 101.1 52.3 17.1 53.6 55.9 121.1 35.7 68.9 37.9 31.6 57.2 82.4 16.7 31.6 26.9 36.5 56.0 34.5 57.9 36.5 34.7 46.5 64.5 55.9 50.2 187.5 85.0 91.9 95.6 124.1 102.7 74.5 86.9 59.2 22.1 143.4 109.5 21.4 45.1 62.9 49.0 59.2 39.5 131.4 67.6 42.2 184.1 165.4 71.2 151.3 91.4 72.3 55.0 63.7 45.3 75.8 36.1 51.8 45.3 87.4 137.8 25.6 147.1 44.4 131.9 86.4 27.1 31.3 128.2 90.2 83.3 57.0 54.0 53.0 75.0 37.2 36.8 55.6 95.5 54.1 75.9 29.0 35.9 56.6 35.4 91.6 88.7 58.6 115.5 41.0 87.6 134.3 336.9 28.5 126.5 31.8 66.8 67.4 26.7 127.7 53.4 79.3 25.6 59.4 54.5 117.4 186.3 67.4 189.0 31.1 32.6 31.7 42.1 32.0 31.0 33.0 32.2 33.6 31.6 31.6 34.7 44.8 67.3 111.1 25.1 73.1 76.0 154.5 107.8 92.2 9.2 103.0 88.9 275.8 338.8 109.5 152.6 14.6 395.0 80.6 140.1 888.3 157.2 8.8 65.9 116.3 61.6 57.2 123.1 9.4 87.2 247.1 129.1 66.3 116.3 41.8 75.1 207.8 1234.6 263.2 8.4 15.0 146.1 236.0 168.8 67.6 23.8 137.0 90.0 204.5 7.5 108.2 197.2 40.2 5.5 19.0 79.7 272.5 210.3 97.4 143.6 409.8 1546.8 38.0 15.3 164.3 45.5 109.3 5.3 11.3 113.6 76.9 381.4 53.0 120.8 147.2 156.9 ADIPOQ "ACDC, ACRP30, adiponectin, apM1, GBP28" ENSG00000181092 "Adiponectin, C1Q and collagen domain containing" Q15848 3 186842704-186858463 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hormone "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 28 "adipose tissue: 898.8;breast: 248.9" "Cell type enhanced" "Detected in single" "Distal tubular cells: 1.9" "Group enriched" "Detected in some" 8 "breast cancer: 6.5;pancreatic cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 672 "ASC diff: 312.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB046467, HPA051767" Uncertain "Secreted to blood" NA NA 8360000000 910000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB046467: AB_1078104, HPA051767: AB_2681598" "unprognostic (1.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.20e-2)" "unprognostic (6.99e-3)" "unprognostic (1.87e-1)" 898.8 8.9 0.1 2.4 0.1 0.2 248.9 0.2 0.1 0.0 0.0 7.7 0.1 0.1 0.0 1.2 0.1 7.6 6.5 0.0 0.0 0.8 0.1 0.1 1.3 0.1 0.0 0.0 6.2 0.1 0.1 0.0 0.1 0.3 6.1 0.1 18.8 0.0 2.3 6.6 8.5 1.2 0.0 0.0 3.9 0.1 0.1 2.2 2.9 20.2 0.0 2.4 0.9 0.3 0.0 0.0 0.0 0.1 312.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADM AM ENSG00000148926 Adrenomedullin P35318 11 10305073-10307397 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 340.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 590.8;Extravillous trophoblasts: 1217.1;Syncytiotrophoblasts: 1084.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "neutrophil: 242.2" "Lineage enriched" "Detected in many" 18 "granulocytes: 242.2" "Cell line enhanced" "Detected in many" "ASC diff: 684.6;fHDF/TERT166: 357.4;HSkMC: 410.9;U-138 MG: 390.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016075, HPA068955" Approved "Secreted to blood" NA NA 31000 340000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB016075: AB_628693, HPA068955: " "unprognostic (1.67e-1)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (1.55e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.78e-3)" "unprognostic (1.06e-1)" "unprognostic (2.83e-1)" "unprognostic (8.13e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (6.33e-4)" "unprognostic (9.70e-3)" "unprognostic (2.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.62e-2)" 340.2 29.9 12.9 32.2 18.3 43.9 195.9 28.1 15.2 162.1 17.9 60.6 8.0 20.3 3.1 84.6 71.0 30.0 153.3 10.6 15.5 123.8 90.5 157.6 17.1 19.7 18.0 33.1 24.6 23.5 43.3 102.8 16.5 26.8 11.4 16.7 52.7 1.6 79.3 169.8 49.5 7.6 16.8 34.5 55.5 4.9 21.6 4.1 52.7 14.3 3.5 85.1 224.3 18.6 35.4 29.2 33.8 9.8 684.6 306.7 51.8 263.6 263.9 260.5 175.7 142.4 43.9 0.1 11.7 357.4 136.9 51.0 9.5 40.6 191.9 0.7 13.9 1.1 16.1 18.0 88.0 1.6 1.1 410.9 34.7 30.8 44.6 89.9 60.4 0.5 0.4 0.7 64.3 1.2 0.2 10.6 65.7 8.4 13.6 1.0 1.1 54.5 16.7 48.6 1.1 3.2 101.0 23.7 0.6 36.4 31.4 0.3 17.9 390.0 5.5 233.2 37.9 2.7 29.5 10.5 112.0 0.2 117.0 0.0 7.0 0.0 0.0 7.7 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.1 242.2 0.0 13.6 0.0 0.3 1.9 12.9 18.3 28.1 15.2 10.6 15.5 19.7 18.0 16.5 16.8 21.6 18.6 347.7 9.6 12.3 17.0 14.2 192.1 590.8 194.4 182.1 2.7 28.0 46.9 104.6 18.6 136.2 3.7 8.4 134.6 9.1 266.7 15.6 135.7 0.5 80.8 58.1 99.1 67.5 4.0 0.4 30.5 1217.1 202.8 55.0 210.9 9.5 30.1 95.7 18.6 71.4 3.3 3.0 127.6 181.0 69.6 57.7 2.6 132.7 107.9 40.9 6.5 8.1 4.9 1.0 1.5 0.1 61.7 298.3 19.2 20.0 218.9 14.0 60.1 38.7 15.3 0.0 73.3 76.5 5.1 4.9 182.3 125.6 1084.8 14.7 8.1 55.5 224.5 AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104345-44114562 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 103.0;Fibroblasts: 263.2;Leydig cells: 151.6;Peritubular cells: 508.9;Smooth muscle cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.6" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.6" "Cell line enhanced" "Detected in many" "ASC diff: 141.1;BJ: 193.0;BJ hTERT+: 126.0;fHDF/TERT166: 208.9;JURKAT: 145.0;WM-115: 117.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 57.6" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2700000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB009966: AB_2225690, HPA047724: AB_2680132, HPA063595: AB_2685052, HPA064970: AB_2685394" "unprognostic (1.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.13e-1)" "unprognostic (7.00e-2)" "unprognostic (8.79e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.31e-9)" "unprognostic (2.88e-3)" "unprognostic (9.58e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-3)" 190.5 59.9 45.0 59.8 56.0 10.6 153.0 38.6 44.8 312.1 28.0 95.3 19.2 268.8 59.6 65.7 199.8 155.9 156.7 47.3 92.9 68.7 20.3 166.0 45.5 114.7 81.5 253.7 28.9 10.1 43.3 89.0 79.6 112.1 25.0 1.3 50.7 213.5 21.3 84.8 79.1 119.3 74.3 54.4 71.2 40.4 52.1 73.3 83.7 14.1 16.7 138.7 198.0 66.6 0.6 0.0 44.5 0.1 141.1 49.6 1.0 193.0 126.0 21.6 4.5 0.0 0.1 5.3 20.9 208.9 0.2 0.1 2.4 3.5 9.1 0.6 0.0 13.3 0.1 0.0 39.6 0.1 0.3 75.8 0.0 72.9 0.1 1.1 9.7 145.0 8.3 0.3 0.0 0.2 86.9 16.1 19.1 0.0 0.4 71.3 1.7 1.7 5.0 0.0 4.9 25.3 0.1 0.3 85.9 41.9 0.4 14.4 34.1 0.0 86.2 0.5 0.3 1.0 0.9 102.8 0.4 0.2 117.9 0.0 0.0 0.0 0.3 0.0 0.2 1.5 0.2 0.0 0.0 1.4 0.9 0.5 0.0 0.1 0.0 7.6 0.0 0.3 45.0 56.0 38.6 44.8 47.3 92.9 114.7 81.5 79.6 74.3 52.1 66.6 23.6 0.0 2.5 32.3 11.8 34.5 5.7 1.3 1.8 0.8 2.0 14.6 26.4 1.5 1.4 7.3 0.0 2.0 22.7 0.0 0.0 0.9 3.1 3.3 103.0 18.0 0.0 1.3 0.1 0.0 3.3 263.2 8.6 2.9 2.5 33.3 30.4 0.6 3.6 0.0 0.3 0.0 0.0 1.8 42.0 18.0 151.6 3.2 85.4 17.8 1.0 0.2 1.0 6.0 0.3 0.4 0.0 508.9 9.7 16.9 0.0 2.2 2.2 0.8 39.5 23.6 173.4 4.0 4.6 1.5 27.4 3.4 4.8 28.7 0.0 2.4 AGPAT1 LPAAT-alpha ENSG00000204310 "1-acylglycerol-3-phosphate O-acyltransferase 1" Q99943 6 32168212-32178096 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 91.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 47.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048478, HPA073355" Approved Supported "Endoplasmic reticulum,Rods & Rings" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "Rods & Rings" "HPA048478: AB_2680411, HPA073355: AB_2686596" "prognostic unfavorable (1.93e-4)" "unprognostic (9.35e-3)" "unprognostic (1.87e-3)" "prognostic unfavorable (5.21e-4)" "unprognostic (4.79e-2)" "unprognostic (7.05e-2)" "unprognostic (7.16e-3)" "unprognostic (1.55e-1)" "unprognostic (3.79e-1)" "unprognostic (4.24e-3)" "unprognostic (1.84e-3)" "unprognostic (1.77e-1)" "unprognostic (6.58e-2)" "unprognostic (1.97e-2)" "unprognostic (2.16e-1)" "unprognostic (9.92e-3)" "unprognostic (7.00e-2)" 46.6 60.3 3.0 5.9 7.2 6.6 42.6 2.5 47.1 58.2 2.9 61.3 28.2 64.3 42.9 33.9 56.5 18.9 66.9 4.0 25.5 61.6 60.2 44.2 10.9 3.8 9.5 67.2 37.5 9.3 53.8 15.9 4.4 53.2 20.1 12.5 34.1 0.0 67.7 35.1 53.0 1.5 2.5 39.8 58.4 79.3 3.3 18.4 54.1 33.5 12.5 58.2 42.7 4.7 0.0 0.4 51.2 0.3 127.5 85.2 49.4 0.0 0.0 0.0 0.0 104.5 0.0 0.0 46.1 128.0 36.4 13.4 108.5 39.4 0.0 0.4 83.6 0.0 0.0 111.7 0.0 0.0 101.5 51.0 47.6 0.0 46.0 105.9 31.6 86.7 78.5 66.0 109.2 28.8 0.4 26.8 0.0 0.1 18.0 0.6 0.0 0.5 32.8 0.0 0.0 0.1 51.3 16.1 70.4 51.6 63.4 0.0 25.9 0.0 20.3 0.0 0.2 45.9 41.1 18.0 64.3 0.1 0.3 3.4 5.6 12.4 7.6 8.2 7.4 5.3 5.0 8.6 9.3 5.0 4.3 6.4 9.4 8.7 5.8 11.6 7.2 6.9 3.0 7.2 2.5 47.1 4.0 25.5 3.8 9.5 4.4 2.5 3.3 4.7 32.1 16.0 18.6 11.1 14.3 9.1 14.0 20.6 16.5 26.1 26.2 21.6 4.0 14.3 12.0 36.8 12.5 35.2 24.5 28.7 5.9 17.9 63.9 14.1 24.9 21.3 29.4 12.0 13.8 14.3 29.9 19.6 16.3 11.4 12.7 22.7 27.1 31.2 24.7 32.0 17.7 24.3 18.3 22.3 20.6 91.7 13.4 24.9 8.8 11.2 13.0 38.5 21.6 10.1 14.8 17.0 22.3 21.4 16.9 10.2 73.6 29.4 12.9 17.9 0.0 18.3 22.9 44.8 22.1 9.5 3.7 15.3 13.8 21.5 20.8 12.1 AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 96.6;placenta: 141.6" "Cell type enhanced" "Detected in some" "Fibroblasts: 53.1;Hepatocytes: 30.9;Leydig cells: 145.1;Sertoli cells: 144.7;Smooth muscle cells: 71.2" "Group enriched" "Detected in many" 8 "breast cancer: 9.6;liver cancer: 9.8;prostate cancer: 6.8;renal cancer: 2.8" "Region enhanced" "Detected in some" "midbrain: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 176.8;ASC TERT1: 24.4;BJ hTERT+ SV40 Large T+: 34.8;HBF TERT88: 53.9;HSkMC: 32.2" "Low region specificity" "Detected in all" HPA003596 Enhanced Uncertain Vesicles NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA003596: AB_1845163" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.48e-4)" "unprognostic (5.28e-3)" "unprognostic (1.55e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-2)" "unprognostic (3.26e-2)" "unprognostic (3.08e-2)" "unprognostic (9.25e-3)" "unprognostic (4.11e-2)" "unprognostic (4.79e-2)" "unprognostic (3.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-3)" 65.9 38.2 0.3 1.8 0.7 0.0 39.9 0.2 0.4 3.4 0.4 21.1 0.8 3.5 2.7 2.8 9.8 6.2 10.9 0.4 1.4 18.4 96.6 10.4 0.7 2.1 8.1 3.8 3.5 2.8 3.8 141.6 0.9 5.3 4.4 0.9 4.7 4.2 11.6 15.8 4.3 4.6 0.2 9.1 6.5 2.2 0.7 3.0 14.2 13.8 0.2 14.6 6.1 0.2 0.0 1.0 0.8 0.0 176.8 24.4 0.0 0.2 3.9 34.8 20.0 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.0 0.0 53.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.2 0.0 3.4 1.8 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.2 0.4 0.4 1.4 2.1 8.1 0.9 0.2 0.7 0.2 20.5 0.0 0.6 0.0 0.0 3.4 0.2 0.0 0.0 0.0 1.3 0.9 6.3 2.8 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.1 0.8 0.0 0.3 3.8 23.5 0.0 0.1 7.6 0.3 53.1 0.5 0.0 0.0 0.0 17.5 30.9 0.7 0.0 0.0 0.2 0.0 0.3 3.5 1.7 145.1 0.5 1.8 2.8 0.0 5.7 0.0 0.0 0.1 0.5 0.0 7.5 0.4 1.1 0.0 0.1 0.0 0.1 144.7 7.6 71.2 0.0 1.8 0.3 1.7 0.3 0.5 0.3 0.0 0.1 AL845331.1 ENSG00000259916 "Putative aquaporin-7-like protein 3" 2 94588522-94604573 "Metabolic proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "adipose tissue: 7.5;breast: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "ASC diff: 1.9" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (8.07e-3)" "unprognostic (1.39e-1)" "unprognostic (1.85e-1)" "unprognostic (1.45e-1)" "unprognostic (1.15e-1)" "unprognostic (9.15e-3)" "unprognostic (6.22e-2)" "unprognostic (4.66e-2)" 7.5 0.1 0.0 0.0 0.5 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALDH1L2 "FLJ38508, mtFDH" ENSG00000136010 "Aldehyde dehydrogenase 1 family member L2" Q3SY69 12 105019784-105107643 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 40.7;salivary gland: 13.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 23.1;Inhibitory neurons: 24.0;Oligodendrocyte precursor cells: 25.1;Plasma cells: 14.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 62.8;ASC TERT1: 85.2;fHDF/TERT166: 102.4;HHSteC: 55.6;HSkMC: 69.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039481, HPA059282" Approved Enhanced Mitochondria No No "Cluster 25: Pancreas - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA039481: AB_10795465, HPA059282: AB_2732633" "unprognostic (5.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-3)" "unprognostic (1.76e-1)" "unprognostic (8.86e-2)" "unprognostic (1.75e-1)" "unprognostic (2.92e-1)" "unprognostic (5.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-8)" "unprognostic (3.21e-3)" "unprognostic (1.33e-1)" "unprognostic (2.53e-3)" "unprognostic (2.52e-5)" 3.7 0.6 1.3 3.1 1.2 0.6 2.3 2.3 1.6 5.3 0.7 2.2 2.6 2.0 1.0 1.3 1.5 2.8 1.9 1.1 1.6 0.4 0.2 1.8 1.0 1.4 1.3 0.6 40.7 0.6 1.3 1.1 1.5 3.6 2.3 0.7 13.0 4.6 0.8 1.0 1.4 4.2 1.8 0.7 3.3 1.1 1.6 0.5 2.1 1.2 1.7 3.4 1.5 2.5 13.0 1.3 0.7 27.3 62.8 85.2 1.6 40.8 26.0 5.2 13.5 1.6 0.0 0.0 1.6 102.4 0.2 0.1 0.1 1.0 6.5 0.0 0.3 0.8 0.1 3.4 55.6 5.3 0.1 69.7 3.1 13.6 25.2 0.0 3.0 0.2 2.1 37.7 10.6 0.0 0.0 0.3 1.6 0.0 0.3 0.0 0.1 4.3 0.0 0.0 9.4 4.5 0.0 8.3 20.5 0.4 6.0 44.0 0.3 3.9 3.8 0.0 2.2 45.5 12.8 0.1 16.2 19.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 1.2 2.3 1.6 1.1 1.6 1.4 1.3 1.5 1.8 1.6 2.5 1.4 0.0 0.6 3.3 2.6 0.5 0.1 0.7 0.0 1.7 0.3 1.1 1.6 0.0 0.2 0.0 0.0 0.2 1.5 0.1 0.0 0.3 4.1 0.7 8.5 0.9 0.0 0.0 23.1 9.8 0.6 10.5 1.5 1.6 0.0 0.1 1.1 0.0 0.4 5.0 24.0 0.0 0.0 0.6 1.7 5.9 3.7 1.0 5.4 1.0 4.0 1.3 0.0 25.1 8.5 3.7 0.0 6.8 14.6 0.4 0.0 0.1 0.2 0.8 0.0 3.6 8.4 1.7 0.1 0.0 0.6 0.3 0.9 0.1 0.1 0.2 ALPK1 "FLJ22670, KIAA1527, Lak" ENSG00000073331 "Alpha kinase 1" Q96QP1 4 112285509-112442621 "Enzymes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 18.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA027435, HPA027443" Approved Approved Centrosome NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Centrosome "HPA027435: AB_10599614, HPA027443: AB_10599421" "unprognostic (6.24e-2)" "unprognostic (1.92e-1)" "unprognostic (9.30e-2)" "unprognostic (1.69e-2)" "unprognostic (7.40e-2)" "unprognostic (5.45e-2)" "unprognostic (2.55e-2)" "unprognostic (7.47e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-1)" "unprognostic (7.14e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (5.82e-7)" "unprognostic (1.60e-1)" "unprognostic (4.17e-2)" "unprognostic (2.81e-1)" "prognostic favorable (1.17e-4)" 4.8 5.3 1.7 4.4 2.0 10.7 5.1 1.9 2.7 5.4 3.2 4.3 2.4 3.7 3.7 4.4 5.3 4.2 3.1 4.5 1.6 7.2 4.5 5.1 5.4 1.4 1.1 5.4 3.5 4.2 2.5 3.6 1.8 4.9 4.2 2.1 5.4 3.1 1.8 6.9 5.0 4.2 0.5 8.7 4.0 2.1 1.8 5.2 4.2 2.3 6.1 6.0 4.4 2.5 1.6 5.0 1.5 0.3 6.4 10.1 2.1 1.7 3.6 2.6 3.3 0.5 7.8 5.3 3.3 3.3 5.2 1.0 1.7 3.2 3.7 6.7 1.9 3.6 2.0 0.4 10.1 2.2 2.0 12.8 8.3 3.7 7.8 5.7 0.9 2.7 0.9 9.1 5.0 3.1 1.3 2.0 0.3 3.7 1.2 0.6 1.1 1.6 3.9 1.8 0.5 0.8 1.7 6.4 2.8 0.2 2.9 4.1 1.8 2.3 2.0 3.8 1.3 2.2 0.7 4.5 5.8 5.3 2.1 1.6 3.7 1.7 0.2 4.7 0.6 0.9 0.6 0.1 3.7 0.9 0.8 0.6 18.7 0.4 2.2 0.5 0.0 1.4 1.7 2.0 1.9 2.7 4.5 1.6 1.4 1.1 1.8 0.5 1.8 2.5 10.8 12.8 26.8 11.4 7.3 2.9 10.9 11.5 12.5 0.5 8.7 10.7 4.0 4.3 15.5 5.5 0.0 4.9 2.9 10.0 0.0 8.0 11.1 12.0 13.7 8.2 1.2 5.0 5.9 6.7 3.0 9.6 16.3 10.9 6.3 10.9 7.1 7.4 10.1 0.0 1.2 8.6 8.2 13.5 4.6 2.6 3.7 18.7 7.2 73.1 16.1 10.7 1.0 0.5 0.7 7.1 9.0 7.5 2.4 8.8 8.0 5.3 25.7 0.2 6.6 8.4 10.8 0.9 0.7 10.3 4.5 7.3 4.0 7.0 6.4 12.4 AMPH ENSG00000078053 Amphiphysin P49418 7 38383704-38631420 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 48.9;pituitary gland: 21.3;retina: 65.9" "Group enriched" "Detected in many" 5 "Bipolar cells: 72.2;Cone photoreceptor cells: 87.6;Excitatory neurons: 228.2;Inhibitory neurons: 198.4;Oligodendrocyte precursor cells: 96.5;Rod photoreceptor cells: 59.4" "Cancer enhanced" "Detected in many" "glioma: 3.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 64.6;ASC TERT1: 37.8;BJ hTERT+ SV40 Large T+: 25.4;BJ hTERT+ SV40 Large T+ RasG12V: 29.9;GAMG: 44.8;HBF TERT88: 23.1;U-138 MG: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008559, HPA019828, HPA019829" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Plasma membrane" "CAB008559: AB_1611845, HPA019828: AB_1844801, HPA019829: AB_1844802" "unprognostic (1.76e-2)" "unprognostic (1.59e-1)" "unprognostic (5.94e-2)" "unprognostic (7.36e-2)" "unprognostic (3.24e-3)" "unprognostic (2.92e-1)" "unprognostic (4.90e-2)" "unprognostic (2.55e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "prognostic favorable (9.96e-4)" "unprognostic (5.06e-2)" "unprognostic (5.81e-5)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" 6.5 1.3 19.2 1.5 21.9 0.0 5.9 7.2 48.9 5.8 0.0 3.7 0.5 4.0 3.4 3.2 4.7 3.0 5.4 27.3 28.8 2.6 0.4 1.0 0.4 11.2 0.8 0.9 1.8 0.3 21.3 0.0 10.9 1.4 1.4 65.9 2.5 2.9 3.6 1.3 1.8 3.8 7.9 1.9 2.8 2.5 5.4 0.7 1.7 9.6 0.2 2.4 2.9 17.5 0.0 0.0 16.7 0.0 64.6 37.8 0.0 2.4 0.0 25.4 29.9 0.0 0.0 0.0 0.0 4.8 44.8 0.0 0.0 0.0 23.1 0.0 2.0 0.2 0.0 0.0 0.0 0.3 0.1 22.4 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.5 0.1 0.3 0.0 0.3 8.5 0.0 0.0 0.0 0.0 1.9 0.0 0.1 4.9 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.0 24.6 17.1 8.8 9.8 0.1 0.3 0.0 16.8 0.3 22.6 0.0 0.2 0.0 0.6 0.0 0.4 0.0 0.2 0.3 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.4 0.0 0.0 19.2 21.9 7.2 48.9 27.3 28.8 11.2 0.8 10.9 7.9 5.4 17.5 0.8 0.0 0.0 22.5 0.6 0.3 0.1 0.0 0.0 72.2 3.1 2.2 7.9 0.0 0.0 0.0 87.6 0.0 0.3 0.0 1.9 0.3 9.9 0.4 3.2 1.1 0.0 0.0 228.2 0.0 0.0 8.6 0.0 0.3 0.0 0.2 3.9 0.1 0.1 1.7 198.4 0.0 0.0 13.0 1.1 15.0 2.8 0.7 0.0 22.5 0.5 7.6 3.1 96.5 5.5 0.1 0.0 4.9 0.1 0.0 0.0 0.0 0.0 59.4 6.6 8.3 8.4 4.7 2.8 0.0 0.3 0.0 0.6 2.0 0.0 0.0 AMY2B AMY2 ENSG00000240038 "Amylase alpha 2B" P19961 1 103553815-103579534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 122 "pancreas: 31246.7" "Cell type enhanced" "Detected in many" "Astrocytes: 56.2;Excitatory neurons: 61.2;Exocrine glandular cells: 148.0;Inhibitory neurons: 48.4;Oligodendrocytes: 41.8" "Cancer enriched" "Detected in many" 15 "pancreatic cancer: 25.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 5.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.8;EFO-21: 10.3" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 77000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (8.69e-4)" "unprognostic (3.71e-3)" "unprognostic (6.41e-2)" "unprognostic (9.75e-2)" "unprognostic (1.32e-1)" "unprognostic (1.51e-4)" "unprognostic (1.21e-2)" "unprognostic (1.63e-2)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-2)" "unprognostic (7.41e-3)" "unprognostic (1.55e-2)" "unprognostic (5.74e-2)" "unprognostic (4.22e-1)" "unprognostic (3.12e-4)" 35.4 24.8 29.5 11.2 34.8 13.4 34.9 39.9 38.6 40.8 19.7 33.0 16.5 22.7 20.2 13.1 50.3 14.1 40.9 27.9 29.5 59.4 39.0 30.2 20.0 27.7 29.1 40.0 31246.7 14.9 36.8 6.9 27.1 35.3 11.9 69.8 256.2 14.6 63.7 42.6 31.7 9.8 26.3 34.8 18.1 5.2 30.6 12.6 63.5 25.2 13.8 29.3 25.8 30.0 0.0 0.5 1.1 0.0 5.6 9.8 1.1 0.8 0.8 0.6 1.5 0.0 0.2 1.0 10.3 0.3 0.0 1.2 0.1 1.3 1.4 1.3 1.6 1.9 4.5 0.8 0.8 2.5 2.6 6.7 6.7 0.8 1.2 1.8 0.2 3.0 0.0 3.2 0.9 0.0 1.9 0.5 0.1 0.1 1.4 0.5 0.0 4.7 5.7 2.0 2.8 0.6 2.4 1.1 0.8 1.8 0.1 1.4 0.8 0.3 0.9 0.5 0.7 3.5 0.1 0.3 1.9 1.8 0.2 0.0 5.0 1.0 0.4 2.5 0.3 1.0 0.1 0.2 1.6 0.9 0.6 0.2 1.2 0.1 2.2 0.5 0.2 1.2 29.5 34.8 39.9 38.6 27.9 29.5 27.7 29.1 27.1 26.3 30.6 30.0 2.8 12.8 20.1 56.2 3.2 4.7 4.2 1.4 0.6 11.7 2.9 2.7 7.2 2.8 11.2 1.8 33.3 0.4 2.4 3.6 0.0 1.3 7.3 1.1 0.6 2.7 4.9 1.3 61.2 148.0 0.4 3.2 2.0 0.7 3.8 0.5 2.2 6.5 1.6 10.1 48.4 2.5 0.0 9.4 3.5 2.7 2.5 3.4 5.4 11.2 4.0 3.1 2.1 22.1 41.8 1.3 2.7 1.9 1.4 1.5 4.3 0.8 14.6 15.4 0.0 1.0 2.5 1.5 0.9 0.4 3.0 0.3 1.7 0.4 2.2 1.6 ANGPT1 "Ang1, KIAA0003" ENSG00000154188 "Angiopoietin 1" Q15389 8 107249482-107498055 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 33.5" "Group enriched" "Detected in many" 4 "Astrocytes: 60.4;Fibroblasts: 20.4;Inhibitory neurons: 37.6;Smooth muscle cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 5.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.8" "Cell line enhanced" "Detected in many" "ASC diff: 87.9;HEL: 53.1;HSkMC: 145.5;U-138 MG: 70.5;WM-115: 47.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017815, HPA018793, HPA018816" Approved "Secreted to blood" NA NA 32000000 110000 "Cluster 1: Neutrophils - Mixed function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB017815: , HPA018793: AB_1844820, HPA018816: AB_1844821" "unprognostic (7.71e-2)" "unprognostic (2.13e-1)" "unprognostic (6.37e-2)" "unprognostic (4.11e-3)" "unprognostic (7.36e-2)" "unprognostic (3.80e-2)" "unprognostic (2.22e-3)" "unprognostic (3.29e-2)" "unprognostic (1.07e-2)" "unprognostic (5.54e-2)" "unprognostic (2.62e-1)" "unprognostic (1.44e-1)" "prognostic favorable (4.40e-4)" "unprognostic (4.56e-3)" "unprognostic (1.69e-1)" "unprognostic (3.24e-1)" "unprognostic (1.76e-1)" 25.1 5.6 3.2 2.6 4.5 0.7 4.6 4.5 2.2 5.8 2.5 3.4 2.3 3.5 4.8 3.5 3.0 13.2 4.8 4.5 6.1 11.1 2.1 21.7 1.4 8.0 3.5 9.5 1.6 1.2 5.8 20.5 4.8 17.7 3.3 0.6 12.0 33.5 23.4 1.2 2.6 3.3 4.8 11.0 4.0 2.3 2.1 2.1 3.5 7.0 1.0 3.9 3.7 11.9 0.0 2.4 9.3 5.3 87.9 30.2 6.6 30.0 25.8 8.1 11.9 6.2 0.1 0.0 0.1 16.0 0.0 0.0 4.2 0.1 10.5 0.0 1.4 53.1 0.6 0.0 24.5 0.7 0.0 145.5 0.0 4.9 0.6 7.5 0.6 0.0 28.2 5.1 10.9 0.0 1.1 7.9 9.6 0.0 1.1 0.0 0.0 3.1 0.0 0.0 0.1 4.2 1.1 0.6 0.0 11.6 2.2 0.0 0.3 70.5 0.9 2.5 0.7 0.2 3.2 0.0 9.7 1.1 47.5 0.1 0.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.8 0.1 0.3 0.0 0.0 0.6 3.2 4.5 4.5 2.2 4.5 6.1 8.0 3.5 4.8 4.8 2.1 11.9 9.0 0.0 2.3 60.4 0.0 0.6 10.1 0.4 5.2 0.9 0.5 2.8 3.3 0.0 2.2 7.3 0.0 5.2 0.0 0.0 1.9 0.3 8.1 0.7 9.1 5.6 0.0 10.1 6.5 0.0 7.6 20.4 1.5 1.9 0.0 0.0 3.3 0.1 0.5 0.0 37.6 0.0 2.0 0.3 1.0 2.4 2.5 2.9 0.0 6.5 1.5 0.5 0.0 3.0 0.6 0.0 0.0 3.8 1.1 1.2 0.0 2.8 0.8 0.0 6.6 3.5 48.6 1.6 5.4 4.0 0.1 2.7 0.8 1.7 0.1 1.2 ANGPTL1 "ANG3, ANGPT3, AngY, ARP1" ENSG00000116194 "Angiopoietin like 1" O95841 1 178849535-178871077 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 133.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 81.7;Leydig cells: 425.9;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "ASC diff: 149.9;ASC TERT1: 60.1;HHSteC: 64.9;HSkMC: 147.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009976 Approved "Secreted to blood" NA NA 380000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009976: AB_1844822" "unprognostic (2.59e-2)" "unprognostic (1.31e-1)" "unprognostic (5.80e-3)" "unprognostic (2.63e-2)" "unprognostic (3.60e-1)" "unprognostic (1.71e-2)" "prognostic favorable (8.73e-4)" "unprognostic (3.81e-2)" "unprognostic (5.78e-3)" "unprognostic (1.47e-1)" "unprognostic (1.39e-1)" "unprognostic (5.31e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.49e-2)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.61e-3)" 56.6 45.1 2.0 10.5 2.7 0.9 26.9 2.3 2.7 21.3 1.5 56.7 9.6 69.2 14.0 33.8 59.0 27.9 22.8 2.9 1.9 17.5 23.9 12.6 3.5 2.1 1.5 68.2 21.9 1.1 2.1 133.8 1.4 12.3 27.5 9.6 36.3 9.5 30.3 9.0 26.7 65.5 2.2 10.9 21.6 15.6 1.7 8.6 41.1 57.3 6.9 23.9 17.1 2.3 0.2 0.0 4.0 0.0 149.9 60.1 0.0 0.1 0.0 0.4 0.8 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 64.9 0.0 0.1 147.5 0.0 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.9 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.1 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 2.7 2.3 2.7 2.9 1.9 2.1 1.5 1.4 2.2 1.7 2.3 16.5 0.0 0.0 9.4 1.3 3.7 0.0 0.0 1.2 2.3 0.8 0.5 3.7 41.5 0.0 1.8 6.2 0.6 0.1 0.0 1.9 2.4 1.4 3.3 40.3 4.1 0.0 0.0 14.8 0.4 0.4 81.7 1.1 5.5 0.0 1.6 8.9 1.0 1.4 0.0 14.9 0.0 0.0 0.0 4.6 10.6 425.9 0.8 3.6 8.4 0.0 31.6 0.0 21.6 0.7 0.0 5.0 212.1 0.4 0.1 0.1 0.1 0.7 10.9 39.5 10.0 51.8 0.8 0.6 0.2 3.7 1.4 0.5 2.7 0.0 0.1 ANGPTL2 "ARP2, HARP" ENSG00000136859 "Angiopoietin like 2" Q9UKU9 9 127087348-127122635 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.4;Endothelial cells: 34.6;Fibroblasts: 99.7;Oligodendrocyte precursor cells: 35.2;Skeletal myocytes: 39.3;Smooth muscle cells: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 140.4;ASC TERT1: 94.9;BJ hTERT+: 205.9;HSkMC: 98.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040933, HPA041299" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 2510000 2200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA040933: AB_10795530, HPA041299: AB_10794552" "unprognostic (5.46e-2)" "unprognostic (4.96e-3)" "unprognostic (1.11e-2)" "unprognostic (2.07e-2)" "unprognostic (8.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.79e-2)" "unprognostic (2.04e-2)" "unprognostic (3.31e-1)" "unprognostic (1.17e-3)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (4.15e-2)" 109.5 11.5 6.1 33.5 12.9 0.2 71.2 15.1 8.6 67.7 12.4 76.5 15.1 72.9 13.7 21.7 31.4 67.0 69.2 6.9 9.4 13.4 14.8 22.5 8.1 12.0 12.4 44.2 5.5 4.1 3.4 21.4 11.7 24.7 17.9 0.9 18.0 27.1 57.6 29.2 27.8 63.4 9.9 49.2 28.9 4.4 12.6 4.7 15.7 36.6 8.9 59.4 49.1 15.4 0.0 0.0 17.4 0.0 140.4 94.9 9.4 8.1 205.9 9.2 8.5 0.0 0.0 0.0 7.0 21.4 1.8 0.1 1.7 0.0 4.8 0.1 0.0 0.0 0.1 0.5 30.3 0.1 0.0 98.2 0.0 20.0 0.0 28.7 27.6 2.3 0.0 0.1 6.3 0.0 0.2 4.3 18.4 0.0 1.0 16.5 27.3 1.6 2.2 0.0 9.3 10.1 0.0 0.0 0.0 3.3 0.0 0.0 8.8 35.5 4.5 50.4 0.0 0.0 0.1 0.0 37.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 12.9 15.1 8.6 6.9 9.4 12.0 12.4 11.7 9.9 12.6 15.4 47.4 9.6 2.4 1.0 0.1 14.3 7.0 0.2 3.4 14.4 0.6 6.6 16.6 0.0 0.1 0.0 2.1 1.0 0.5 0.1 0.0 0.2 1.6 1.4 20.2 34.6 0.0 0.0 0.6 0.0 0.8 99.7 1.1 1.0 0.0 2.9 5.0 0.0 1.4 0.0 1.5 0.0 0.0 0.0 17.4 1.5 20.8 0.8 7.2 1.9 0.0 1.9 0.0 35.2 19.2 1.2 0.0 6.4 0.0 1.7 0.0 2.4 1.6 0.8 0.0 39.3 43.5 1.0 0.0 1.4 11.1 2.6 1.7 1.1 0.0 0.6 ANGPTL5 ENSG00000187151 "Angiopoietin like 5" Q86XS5 11 101890674-101916522 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "ovary: 22.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 19.4;Langerhans cells: 11.3;Leydig cells: 27.7;Melanocytes: 7.2;Peritubular cells: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "ASC diff: 2.7" "Region enhanced" "Detected in some" "spinal cord: 3.3" HPA038516 Uncertain "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA038516: AB_10672749" "unprognostic (8.28e-3)" "unprognostic (3.08e-2)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (3.23e-2)" "unprognostic (2.18e-1)" "unprognostic (4.88e-2)" "unprognostic (6.74e-4)" "unprognostic (1.96e-1)" "unprognostic (1.53e-8)" "unprognostic (3.40e-2)" "unprognostic (1.95e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-3)" 4.3 0.2 0.1 0.0 0.2 0.0 5.5 0.2 0.4 0.2 0.4 0.3 0.1 0.0 4.4 0.2 0.3 0.2 2.7 0.2 0.2 0.0 0.0 0.9 0.1 0.2 0.1 22.4 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.4 0.2 0.4 2.4 0.2 0.0 0.2 0.0 0.1 1.6 0.1 0.0 0.7 1.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 2.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.5 0.0 0.0 0.3 0.0 6.2 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.0 0.0 2.1 0.9 0.6 0.8 0.0 0.0 2.7 0.0 0.1 19.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.0 11.3 0.8 27.7 0.1 7.2 4.7 0.0 0.2 0.0 1.0 0.2 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.2 1.0 0.2 0.2 0.0 5.5 0.1 0.5 5.7 0.0 0.0 ANKRD53 "FLJ12056, FLJ36160" ENSG00000144031 "Ankyrin repeat domain 53" Q8N9V6 2 70978380-70985499 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.5" "Group enriched" "Detected in many" 21 "Early spermatids: 158.6;Late spermatids: 481.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.0" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HHSteC: 1.6;HSkMC: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA049574 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA049574: AB_2680819" "unprognostic (6.11e-3)" "unprognostic (6.51e-2)" "unprognostic (1.70e-3)" "unprognostic (2.68e-1)" "unprognostic (2.01e-2)" "unprognostic (6.31e-3)" "unprognostic (2.20e-1)" "unprognostic (6.35e-2)" "unprognostic (3.53e-1)" "unprognostic (1.27e-1)" "unprognostic (6.39e-3)" "unprognostic (1.83e-1)" "unprognostic (1.13e-2)" "unprognostic (1.68e-3)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" 7.5 1.7 0.3 0.6 0.2 0.3 6.1 1.5 0.5 1.8 0.0 1.9 0.7 1.8 0.4 0.7 3.0 0.7 1.3 0.3 0.2 0.8 0.6 1.3 0.3 0.8 0.4 4.1 8.2 0.3 3.2 0.3 0.2 2.0 0.2 6.1 4.5 0.6 0.4 0.8 1.7 0.6 0.3 0.8 2.0 27.5 0.1 0.1 3.1 0.3 0.3 1.6 1.6 0.2 0.0 0.0 0.1 0.1 1.0 0.4 0.1 0.1 0.4 0.4 0.4 0.2 0.0 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.6 0.0 0.0 1.6 0.0 0.4 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.2 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.3 0.2 1.5 0.5 0.3 0.2 0.8 0.4 0.2 0.3 0.1 0.2 1.1 0.0 0.0 0.3 1.1 0.1 1.4 0.5 4.6 1.3 0.3 1.3 0.4 1.5 0.1 0.0 2.1 0.1 1.0 0.0 0.0 1.2 158.6 4.3 0.5 0.7 0.0 0.4 0.4 0.4 1.0 1.9 1.1 2.2 0.0 0.4 1.1 0.2 0.0 1.7 1.2 0.0 0.0 0.0 0.4 481.3 3.4 0.4 0.0 0.0 0.0 4.1 0.0 1.5 0.3 0.5 0.0 3.0 11.7 0.7 0.1 1.5 0.6 15.1 6.6 2.8 1.5 1.5 1.7 0.6 0.0 0.3 0.4 0.1 0.1 0.1 ANPEP "CD13, gp150, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784895-89815401 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 2384.1;pancreas: 675.0" "Cell type enriched" "Detected in many" 14 "Proximal enterocytes: 6315.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "cerebral cortex: 9.2;thalamus: 17.4" "Immune cell enriched" "Detected in many" 4 "neutrophil: 227.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 227.1" "Cell line enhanced" "Detected in many" "ASC diff: 613.7;ASC TERT1: 764.2;BJ: 738.4;BJ hTERT+: 1135.6;fHDF/TERT166: 703.8;HMC-1: 660.3;HSkMC: 670.0;HUVEC TERT2: 874.8;TIME: 815.1;U-2197: 891.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 14.8" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" NA NA 1200000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002417: AB_563491, HPA004625: AB_2667199" "unprognostic (6.31e-2)" "unprognostic (7.94e-3)" "unprognostic (6.91e-2)" "unprognostic (2.16e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (7.73e-2)" "unprognostic (5.28e-3)" "unprognostic (3.96e-1)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-2)" 55.4 7.0 1.6 36.6 1.6 103.4 55.9 1.3 9.2 41.4 3.4 266.8 2384.1 3.6 1.7 4.8 8.0 120.3 6.9 1.3 1.5 249.7 271.8 34.3 12.8 1.5 2.1 1.9 675.0 0.8 1.9 33.1 2.5 94.0 59.9 0.0 42.1 5.5 2.5 32.5 1970.6 29.7 1.3 25.9 8.0 2.0 17.4 7.1 8.2 3.8 4.7 16.8 15.0 1.2 0.1 45.6 0.0 0.5 613.7 764.2 6.2 738.4 1135.6 95.3 81.6 5.8 0.4 0.2 8.4 703.8 0.0 0.6 5.6 0.2 38.6 0.1 0.1 137.3 4.6 122.8 352.0 11.4 660.3 670.0 1.4 302.3 0.3 4.4 874.8 0.0 3.8 0.8 37.8 0.1 0.6 355.4 1.9 0.0 49.9 0.3 0.1 9.5 449.2 0.0 1.2 7.2 0.1 1.3 0.1 1.8 0.5 72.1 815.1 385.3 0.6 891.4 0.1 0.4 0.1 0.1 0.9 0.9 20.5 22.2 56.3 41.1 0.1 27.4 0.0 0.2 0.0 0.0 26.2 0.2 0.0 0.0 227.1 0.0 49.7 0.7 0.0 25.7 1.6 1.6 1.3 9.2 1.3 1.5 1.5 2.1 2.5 1.3 17.4 1.2 2.4 0.0 3.0 0.0 5.2 9.9 2.8 1.4 0.6 0.0 35.7 12.8 1.2 391.7 19.7 20.2 0.0 13.0 0.7 429.8 43.0 15.4 0.2 0.5 10.1 8.4 3.0 6.6 0.3 386.2 16.3 31.0 0.0 0.4 24.1 0.3 79.2 192.4 37.5 0.0 0.3 199.6 2.0 54.1 63.2 0.2 2.8 71.9 3.6 0.0 38.3 0.0 0.0 0.0 0.1 75.5 316.9 1.5 2.1 20.9 6315.2 435.0 3.3 0.0 26.3 0.8 8.1 0.3 0.5 0.2 5.8 6.4 3.7 187.8 290.9 1.4 ANXA6 ANX6 ENSG00000197043 "Annexin A6" P08133 5 151100706-151157785 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 343.8;monocytes: 445.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 861.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002462, CAB005077, HPA009650, HPA009977" Enhanced Approved Cytosol NA NA 1800000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB005077: AB_630873, HPA002462: AB_1078166, HPA009650: AB_1844867, HPA009977: " "unprognostic (1.74e-1)" "unprognostic (5.85e-2)" "unprognostic (1.03e-1)" "unprognostic (5.81e-2)" "unprognostic (2.44e-1)" "unprognostic (9.41e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-1)" "unprognostic (9.63e-2)" "unprognostic (1.60e-2)" "unprognostic (1.08e-3)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.31e-5)" "unprognostic (6.29e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-3)" "unprognostic (1.38e-3)" 292.9 135.4 98.1 164.2 104.1 109.7 188.3 94.0 150.6 148.9 151.8 196.0 44.5 181.5 105.0 94.7 149.9 108.7 188.7 102.5 123.1 82.6 214.4 131.6 161.8 144.2 109.4 181.7 78.3 29.6 161.9 141.1 146.2 124.9 78.2 133.6 70.3 208.6 331.3 62.7 119.9 300.1 92.3 150.9 111.4 52.5 127.4 160.8 86.7 371.5 176.4 206.5 107.4 104.8 3.0 30.4 212.8 317.1 861.2 417.8 55.1 397.4 526.4 323.5 477.6 106.7 15.6 26.9 138.5 578.6 268.1 0.5 165.9 200.2 300.3 110.5 52.1 15.3 62.1 204.7 295.0 97.6 94.7 508.6 1.5 282.3 42.0 476.9 420.6 197.5 22.0 396.1 737.6 100.4 181.8 151.7 56.2 1.2 92.4 120.4 592.9 31.0 42.2 0.3 12.2 49.3 39.9 282.7 175.6 308.4 488.3 201.1 326.8 296.6 84.2 19.4 107.1 205.4 289.5 4.5 154.5 459.7 46.2 89.7 89.4 82.9 290.4 54.7 190.4 175.4 213.4 263.3 118.3 179.0 145.8 181.6 17.6 261.9 25.0 30.2 190.9 331.7 98.1 104.1 94.0 150.6 102.5 123.1 144.2 109.4 146.2 92.3 127.4 104.8 90.3 16.0 17.3 19.2 146.8 11.0 11.5 2.2 1.8 16.5 30.7 24.0 59.5 12.8 1.1 23.9 6.2 64.3 110.3 0.3 25.4 6.5 56.9 1.8 38.5 45.6 21.4 36.4 36.5 17.8 33.7 105.9 9.2 1.7 57.5 343.8 57.1 147.1 85.4 15.2 36.3 2.4 0.0 41.0 77.8 46.8 123.3 41.2 55.2 10.3 445.2 45.6 187.4 18.6 5.6 12.1 1.2 211.4 120.3 7.3 1.0 48.4 4.7 125.8 230.1 55.3 150.6 2.5 1.5 0.6 8.1 177.2 143.4 149.4 2.5 1.5 AOC2 "DAO2, RAO" ENSG00000131480 "Amine oxidase copper containing 2" O75106 17 42844580-42850707 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Early spermatids: 29.5" "Cancer enhanced" "Detected in some" "testis cancer: 3.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "ASC diff: 11.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA057779 Uncertain "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "HPA057779: " "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (5.10e-4)" "unprognostic (1.90e-2)" "unprognostic (1.48e-2)" "unprognostic (2.42e-1)" "unprognostic (4.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.39e-1)" "unprognostic (3.64e-2)" "unprognostic (2.16e-2)" "unprognostic (8.27e-3)" "unprognostic (4.55e-5)" "unprognostic (3.55e-2)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.47e-4)" 5.8 1.1 1.9 0.6 2.1 0.9 2.6 1.9 3.2 1.3 0.6 1.3 0.3 1.0 0.5 0.7 1.6 0.7 0.7 2.4 1.9 1.2 3.4 2.3 0.5 2.0 1.6 1.1 0.7 0.2 2.0 0.4 2.0 1.5 0.2 1.5 0.6 0.5 1.6 1.3 0.8 0.6 1.1 1.6 0.8 4.8 2.0 0.3 0.9 0.6 0.6 1.8 1.2 1.9 0.2 2.3 0.5 2.5 11.2 1.1 6.0 0.8 0.7 1.6 2.2 1.8 0.2 0.9 1.1 0.2 0.7 1.0 2.2 0.6 3.2 2.0 6.0 0.3 1.3 1.9 0.7 0.3 2.2 1.7 2.0 1.5 2.3 0.4 0.4 3.1 0.6 2.1 0.4 0.3 0.5 0.9 0.8 0.2 0.7 1.1 2.3 1.9 0.3 3.6 0.8 0.5 0.1 0.8 3.4 4.6 0.4 0.2 0.4 1.5 3.2 2.0 1.0 4.6 4.9 0.9 0.4 2.2 0.8 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.9 2.1 1.9 3.2 2.4 1.9 2.0 1.6 2.0 1.1 2.0 1.9 1.1 0.0 0.5 1.6 0.3 1.0 0.5 0.1 0.0 0.5 0.9 0.9 0.4 0.0 0.7 0.0 2.1 0.1 0.4 0.0 0.0 0.3 29.5 1.4 0.7 1.4 0.0 0.0 1.8 0.4 0.1 0.2 0.0 2.8 0.0 0.5 0.4 0.7 0.1 0.0 1.2 0.2 0.0 0.3 0.6 5.0 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.2 0.1 0.0 0.0 1.2 0.1 0.2 0.4 0.8 0.0 0.5 1.0 2.3 2.1 0.4 1.6 0.0 0.2 0.4 0.2 0.6 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 422.8" "Group enriched" "Detected in many" 4 "Adipocytes: 58.2;Peritubular cells: 74.9;Sertoli cells: 118.3;Smooth muscle cells: 93.0;Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "ASC diff: 307.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" NA NA 240000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" 422.8 48.4 2.6 31.9 3.2 1.4 169.2 2.5 4.2 52.8 2.7 210.8 17.3 95.1 33.5 88.0 84.8 50.7 50.2 2.9 2.5 24.1 19.1 218.6 12.4 2.5 2.5 26.5 12.0 8.4 5.4 28.0 2.6 59.1 41.0 1.7 14.7 103.6 17.8 24.6 57.6 144.8 2.3 21.4 66.6 12.8 2.4 5.9 28.2 22.9 3.9 142.1 50.9 2.5 0.1 1.5 0.2 1.0 307.5 0.3 5.0 0.3 0.1 0.2 0.8 0.9 0.0 0.7 0.7 0.1 0.2 0.5 0.8 0.2 0.8 1.5 5.7 0.4 0.5 18.4 0.8 0.3 1.0 3.3 1.0 0.3 0.8 0.0 0.2 2.2 0.3 1.7 0.6 0.2 0.2 1.4 0.7 0.1 0.4 0.7 0.8 3.0 0.1 2.2 0.3 0.4 0.0 0.2 2.0 2.2 0.1 0.1 0.0 0.3 2.7 1.2 0.4 4.8 5.9 0.6 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 3.2 2.5 4.2 2.9 2.5 2.5 2.5 2.6 2.3 2.4 2.5 58.2 3.2 6.0 0.0 0.5 2.9 0.1 0.0 2.2 0.0 1.1 2.2 9.5 0.0 1.9 0.0 0.0 0.1 0.4 0.1 0.0 0.2 4.5 0.8 2.3 12.3 0.0 0.0 0.4 0.2 0.1 11.3 0.0 1.4 1.3 2.1 20.7 0.2 1.4 0.0 0.3 0.1 0.0 1.4 2.7 2.6 3.4 0.9 3.6 3.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 74.9 0.0 0.4 0.1 1.4 1.0 0.4 118.3 2.6 93.0 1.1 1.3 0.7 1.8 0.3 0.6 74.6 0.1 0.3 AOX1 "AO, AOH1" ENSG00000138356 "Aldehyde oxidase 1" Q06278 2 200586014-200677064 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 300.5;liver: 891.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 749.1" "Cancer enriched" "Detected in many" 9 "liver cancer: 122.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 377.3;ASC TERT1: 191.5;HSkMC: 78.2;hTERT-HME1: 81.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040199, HPA040215" Enhanced NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA040199: AB_10795273, HPA040215: AB_10795360" "unprognostic (4.39e-2)" "unprognostic (1.03e-3)" "unprognostic (1.96e-1)" "unprognostic (3.15e-2)" "unprognostic (1.17e-4)" "unprognostic (1.92e-2)" "unprognostic (2.34e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-2)" "unprognostic (5.48e-2)" "unprognostic (2.00e-2)" "prognostic favorable (6.05e-5)" "unprognostic (1.33e-2)" "unprognostic (8.16e-3)" "unprognostic (3.38e-2)" "unprognostic (4.99e-3)" 87.6 300.5 0.6 3.2 2.9 0.5 50.2 0.1 2.4 17.9 3.6 12.0 0.8 10.8 12.3 8.2 48.2 9.9 14.9 1.1 1.5 103.2 891.0 19.5 4.7 1.3 1.0 48.0 85.0 1.3 2.8 1.7 1.2 22.3 4.5 0.5 15.3 28.3 12.9 20.1 12.7 7.1 0.5 4.1 14.3 19.4 4.0 2.0 17.7 11.0 1.5 38.6 17.7 3.6 0.6 0.2 0.0 0.0 377.3 191.5 0.2 6.6 12.2 5.4 9.7 0.0 0.1 0.1 0.5 8.4 2.3 0.2 0.1 18.6 22.0 0.2 0.6 0.0 4.6 20.7 25.4 0.9 0.0 78.2 4.6 26.1 81.2 5.4 0.2 0.2 0.2 0.1 18.3 0.5 0.0 0.1 8.0 0.1 5.2 0.0 0.5 0.1 0.2 0.2 0.4 0.3 4.8 0.0 0.3 0.4 0.1 0.2 31.9 13.8 11.2 0.2 2.5 0.2 0.1 2.6 10.7 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.1 2.4 1.1 1.5 1.3 1.0 1.2 0.5 4.0 3.6 1.0 3.2 1.1 0.7 3.6 1.8 0.5 1.2 1.2 0.1 0.2 0.3 0.9 17.2 0.1 3.7 0.0 0.1 0.0 0.1 11.7 0.7 0.8 0.4 3.0 2.6 3.0 37.5 0.9 26.2 0.2 22.9 0.0 8.2 0.0 0.1 15.4 749.1 0.4 0.0 2.5 0.1 2.0 19.8 3.6 4.4 74.0 1.7 3.6 1.0 0.0 0.6 0.0 5.0 6.9 11.5 0.0 82.0 0.0 7.5 0.1 162.2 0.1 0.1 0.0 5.3 3.0 0.8 1.3 0.1 1.6 0.0 2.0 2.3 0.1 0.4 AP3S1 CLAPS3 ENSG00000177879 "Adaptor related protein complex 3 subunit sigma 1" Q92572 5 115841592-115914081 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049270 Uncertain Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA049270: AB_2680696" "prognostic unfavorable (1.22e-4)" "unprognostic (2.54e-2)" "unprognostic (8.05e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (3.33e-4)" "unprognostic (2.60e-2)" "unprognostic (3.83e-3)" "unprognostic (4.42e-3)" "unprognostic (1.36e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.57e-8)" "unprognostic (2.73e-2)" "unprognostic (3.62e-2)" "unprognostic (2.75e-1)" "unprognostic (1.64e-1)" 63.1 44.5 57.0 38.7 59.7 133.3 60.1 55.2 84.5 70.1 54.6 53.7 61.9 55.1 113.6 65.8 46.1 49.2 52.6 61.5 60.7 37.4 74.7 38.1 64.6 62.3 60.3 69.6 63.2 24.9 19.7 60.1 62.8 43.6 60.1 34.0 59.4 85.6 21.9 60.7 81.5 64.1 59.1 39.0 37.7 57.3 58.4 41.1 49.3 34.4 61.1 60.2 25.4 59.5 134.3 44.8 95.2 63.4 257.4 369.1 89.2 142.6 132.4 94.1 152.0 98.9 121.4 107.5 68.4 162.8 115.4 38.1 58.8 230.4 157.6 320.3 114.4 45.1 43.8 146.2 139.8 76.2 84.6 168.6 177.9 100.2 112.1 123.5 109.4 122.1 47.1 80.9 150.3 49.9 87.3 129.0 71.1 65.5 74.4 85.0 141.9 172.0 123.2 58.8 35.1 53.8 222.8 42.7 146.3 86.2 70.3 116.1 115.4 173.1 116.5 127.1 113.4 71.6 47.3 91.8 129.9 144.2 73.5 81.9 70.7 174.8 37.6 79.2 63.7 67.1 47.1 52.3 54.5 47.3 39.9 41.6 110.0 48.3 75.8 94.8 60.3 70.6 57.0 59.7 55.2 84.5 61.5 60.7 62.3 60.3 62.8 59.1 58.4 59.5 75.6 22.4 21.9 31.3 90.1 203.0 92.8 308.5 95.0 68.0 72.9 59.3 26.4 67.2 115.0 46.0 25.0 74.1 95.0 129.7 70.5 93.6 130.2 37.8 62.1 73.9 76.1 31.7 83.1 86.5 309.4 158.3 43.8 35.1 83.6 39.6 81.8 87.2 152.6 26.9 61.2 131.5 105.8 111.7 185.7 217.4 173.1 88.4 115.6 68.4 103.9 19.6 74.2 46.3 49.9 111.4 105.5 111.3 103.6 118.3 361.1 156.7 59.8 77.7 32.9 48.2 118.0 108.8 104.7 131.5 227.9 128.7 79.0 60.7 74.9 112.5 APH1B "APH-1B, DKFZp564D0372, PSFL" ENSG00000138613 "Aph-1 homolog B, gamma-secretase subunit" Q8WW43 15 63276018-63309126 "Predicted membrane proteins, Transporters" "Notch signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 122.8" "Group enriched" "Detected in many" 15 "Early spermatids: 1363.2;Late spermatids: 359.9;Spermatocytes: 838.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 107.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (9.92e-2)" "unprognostic (1.03e-2)" "unprognostic (1.49e-1)" "unprognostic (1.75e-1)" "unprognostic (3.55e-2)" "unprognostic (3.57e-1)" "unprognostic (7.86e-2)" "unprognostic (1.78e-1)" "unprognostic (3.86e-1)" "unprognostic (4.56e-2)" "prognostic favorable (1.05e-4)" "unprognostic (8.44e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.29e-3)" "unprognostic (2.54e-1)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" 10.1 12.1 9.4 9.7 10.9 8.1 10.6 9.8 10.8 8.4 10.9 6.0 3.8 6.9 11.6 3.8 16.2 7.5 5.7 8.2 10.0 7.7 3.4 8.8 10.1 10.6 11.8 14.6 4.5 7.4 6.9 8.1 10.7 11.7 4.4 12.2 8.2 8.0 4.0 5.4 7.7 6.4 11.6 13.6 5.1 122.8 10.3 9.7 19.5 5.6 7.8 7.7 6.7 12.7 1.3 8.8 9.3 7.5 20.7 36.2 3.3 11.2 22.6 8.3 13.9 8.1 12.3 11.1 5.2 12.4 15.4 1.2 15.8 4.4 15.5 7.6 2.5 19.6 1.9 0.3 17.1 4.3 30.9 22.8 7.0 12.3 8.3 14.1 17.6 13.9 6.7 8.0 26.1 3.9 5.9 13.2 8.8 2.8 4.6 5.7 5.1 0.2 4.3 8.9 8.1 4.4 4.5 3.7 0.1 9.8 13.6 25.1 11.8 24.5 9.4 4.0 1.6 19.6 35.3 15.2 17.8 25.1 14.6 32.0 31.8 41.4 10.7 63.1 9.0 24.1 10.8 9.7 15.3 18.0 11.8 12.0 44.1 6.2 107.5 5.5 11.7 18.6 9.4 10.9 9.8 10.8 8.2 10.0 10.6 11.8 10.7 11.6 10.3 12.7 8.4 9.6 18.8 16.3 21.7 5.2 12.4 15.5 5.7 6.8 16.2 13.7 6.1 11.5 15.9 22.0 2.1 6.3 10.4 1.0 1.9 36.9 1363.2 25.6 12.7 12.0 20.4 5.0 18.1 6.2 38.7 18.1 4.6 4.5 22.8 12.5 17.9 1.7 55.7 1.7 22.9 4.1 22.4 52.0 17.7 359.9 24.5 41.8 10.6 16.9 29.6 21.4 6.2 27.2 28.9 11.1 0.8 16.6 16.3 8.9 0.7 6.8 38.6 14.8 13.1 12.6 15.5 838.0 20.0 2.3 3.4 6.0 14.5 16.4 2.8 9.0 APOD ENSG00000189058 "Apolipoprotein D" P05090 3 195568705-195584033 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 5037.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 4485.3;Leydig cells: 2077.4;Melanocytes: 1028.1;Peritubular cells: 994.5" "Cancer enriched" "Detected in all" 4 "melanoma: 925.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "memory B-cell: 5.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.0" "Group enriched" "Detected in many" 6 "ASC diff: 3507.4;ASC TERT1: 1918.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040520 Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 98900000000 90000000000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA040520: AB_2677020" "prognostic favorable (5.51e-4)" "unprognostic (7.62e-3)" "unprognostic (7.85e-3)" "unprognostic (3.34e-3)" "unprognostic (2.20e-1)" "unprognostic (1.02e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.38e-1)" "unprognostic (3.19e-1)" "unprognostic (6.90e-3)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.71e-3)" 2071.8 84.8 949.6 13.9 1157.3 0.9 5037.8 1174.9 1364.1 620.2 1370.1 144.7 56.0 496.7 155.7 160.0 750.6 213.3 1007.8 952.8 1010.4 49.7 7.1 183.5 24.6 1148.3 1040.5 131.2 212.4 61.9 192.2 350.5 1122.0 419.8 57.2 0.8 1272.3 183.8 1154.9 970.1 88.4 96.2 1027.5 8.2 402.6 75.7 1070.2 113.5 828.8 625.3 20.8 434.4 591.7 1347.6 0.0 2.2 0.5 0.7 3507.4 1918.1 6.1 31.3 7.6 0.1 0.2 222.4 0.4 0.4 0.9 1.8 0.0 0.9 0.4 10.5 0.3 0.3 2.4 0.3 0.2 0.1 12.5 0.3 0.5 91.4 21.0 0.2 17.0 0.3 4.3 0.2 0.2 0.9 5.3 1.3 0.1 0.7 0.5 38.9 0.5 0.1 0.0 0.6 0.0 2.8 0.7 0.5 0.0 34.8 31.8 1.3 67.2 0.1 0.4 0.5 1.4 0.4 0.1 0.2 0.3 9.2 1.0 0.4 420.3 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 949.6 1157.3 1174.9 1364.1 952.8 1010.4 1148.3 1040.5 1122.0 1027.5 1070.2 1347.6 543.2 0.0 11.0 2.9 7.5 145.0 16.0 25.4 46.7 0.0 121.6 138.7 26.9 1.5 81.8 5.5 0.0 5.4 15.9 1.4 0.0 0.4 9.7 16.3 393.7 114.1 46.3 0.0 3.3 0.0 4.2 4485.3 7.7 7.0 0.0 0.0 21.4 0.0 13.3 0.0 2.1 0.7 10.2 0.3 193.2 51.0 2077.4 31.8 1028.1 279.2 1.0 0.0 0.0 300.6 221.5 2.3 0.3 994.5 19.2 25.7 0.0 0.2 128.9 0.0 19.7 100.3 210.7 10.5 4.0 24.1 102.6 5.9 23.5 7.0 0.6 47.3 AQP7 "AQP7L, AQP9, AQPap" ENSG00000165269 "Aquaporin 7" O14520 9 33383179-33402682 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 252.7;breast: 104.9;heart muscle: 108.5" "Cell type enhanced" "Detected in many" "Adipocytes: 129.7;Cardiomyocytes: 86.0;Early spermatids: 128.5;Proximal enterocytes: 160.7;Proximal tubular cells: 61.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 43 "ASC diff: 196.0" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.25e-2)" "unprognostic (3.81e-3)" "unprognostic (1.25e-5)" "unprognostic (7.22e-3)" "unprognostic (1.50e-1)" "unprognostic (3.32e-1)" "unprognostic (4.67e-2)" "unprognostic (3.06e-2)" "unprognostic (9.99e-2)" "unprognostic (4.65e-2)" "unprognostic (8.56e-4)" "unprognostic (1.21e-1)" "prognostic favorable (9.21e-8)" "unprognostic (2.42e-1)" "unprognostic (1.28e-1)" "unprognostic (1.61e-1)" "unprognostic (2.12e-3)" 252.7 5.0 0.9 1.9 1.3 0.0 104.9 4.4 1.4 1.3 0.0 6.6 17.9 1.7 2.9 2.8 5.9 3.4 108.5 0.8 0.7 24.2 23.5 1.2 0.7 4.8 0.7 1.8 3.8 18.3 0.3 0.5 5.8 1.2 4.0 0.3 6.4 2.5 33.8 6.2 26.8 2.5 0.3 1.3 2.8 30.4 1.0 1.0 4.8 51.9 0.2 4.7 2.2 1.2 0.1 1.9 0.2 0.1 196.0 4.5 0.2 0.0 0.0 0.0 0.0 2.2 0.1 0.2 0.1 0.1 0.1 0.3 0.1 1.1 0.0 0.1 0.0 0.1 0.4 2.2 0.2 0.0 0.2 3.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 4.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.9 1.3 4.4 1.4 0.8 0.7 4.8 0.7 5.8 0.3 1.0 1.2 129.7 6.4 7.3 0.3 0.2 1.5 0.3 0.3 0.0 0.0 0.8 1.5 86.0 14.3 0.9 35.0 0.0 0.0 0.6 30.7 5.9 1.9 128.5 9.1 0.2 11.2 0.0 0.0 0.1 0.2 0.3 4.1 0.0 0.7 0.0 0.2 2.9 20.1 0.1 0.0 0.1 9.2 0.0 0.3 0.3 21.4 2.1 1.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.2 22.5 1.9 0.1 0.5 160.7 61.4 7.7 0.0 6.6 1.7 9.6 4.1 0.7 1.3 2.6 0.0 0.3 0.9 4.3 2.1 ARHGAP20 KIAA1391 ENSG00000137727 "Rho GTPase activating protein 20" Q9P2F6 11 110577042-110713189 "Disease related genes, Predicted intracellular proteins" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.0;Excitatory neurons: 97.9;Inhibitory neurons: 159.9;Leydig cells: 48.7;Oligodendrocyte precursor cells: 90.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 24.6;ASC TERT1: 8.2;HHSteC: 5.5;SiHa: 7.2;U-2197: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038458, HPA038459, HPA076303" Uncertain Approved Mitochondria NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA038458: AB_10672517, HPA038459: AB_2676022, HPA076303: AB_2686792" "unprognostic (1.69e-2)" "unprognostic (3.97e-2)" "unprognostic (6.83e-2)" "unprognostic (1.34e-1)" "unprognostic (2.66e-1)" "unprognostic (8.47e-3)" "unprognostic (2.75e-1)" "unprognostic (2.90e-2)" "unprognostic (4.15e-2)" "unprognostic (5.70e-2)" "unprognostic (1.38e-1)" "unprognostic (9.52e-2)" "unprognostic (2.82e-5)" "unprognostic (1.84e-2)" "unprognostic (9.15e-2)" "unprognostic (6.21e-3)" "unprognostic (4.10e-2)" 8.9 2.3 3.8 1.3 4.1 0.0 4.5 1.8 3.5 4.4 0.3 1.9 0.8 4.4 3.6 2.2 3.1 2.2 0.4 3.5 2.5 0.3 1.7 4.1 1.2 0.5 0.7 1.2 0.2 0.8 0.9 1.7 0.5 3.9 2.8 1.1 1.3 8.8 0.9 1.0 1.5 3.3 1.2 1.3 1.8 8.3 2.0 0.4 4.8 1.3 0.8 3.2 2.2 0.8 0.0 0.0 0.0 0.0 24.6 8.2 0.0 1.1 3.3 0.4 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.3 0.0 5.5 0.0 0.0 3.0 0.0 0.0 0.0 0.1 2.4 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.3 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.4 0.0 0.1 0.0 2.1 0.9 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 4.1 1.8 3.5 3.5 2.5 0.5 0.7 0.5 1.2 2.0 0.8 1.7 0.0 2.3 5.2 1.7 0.8 4.9 1.1 10.2 9.9 0.5 6.0 0.9 1.5 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 13.1 1.7 78.0 4.3 0.0 0.0 97.9 0.4 0.1 15.1 0.0 1.2 1.3 1.1 9.7 2.0 0.2 3.3 159.9 0.2 0.0 0.8 1.6 4.6 48.7 2.1 3.6 22.5 0.0 0.7 0.0 90.0 3.2 0.7 0.0 36.5 1.2 1.9 0.0 0.0 0.0 1.4 0.0 2.3 4.6 11.8 11.7 1.6 0.4 0.7 0.5 3.6 0.0 0.8 ARHGEF40 "FLJ10357, solo" ENSG00000165801 "Rho guanine nucleotide exchange factor 40" Q8TER5 14 21070273-21090248 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030745, HPA030746, HPA030757" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA030745: , HPA030746: AB_10599613, HPA030757: AB_10600203" "unprognostic (6.30e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-1)" "unprognostic (5.91e-2)" "unprognostic (2.55e-1)" "unprognostic (8.16e-3)" "unprognostic (1.27e-2)" "unprognostic (9.84e-3)" "unprognostic (1.33e-1)" "unprognostic (8.80e-2)" "unprognostic (1.64e-2)" "unprognostic (2.53e-1)" "unprognostic (6.01e-3)" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (2.33e-1)" "unprognostic (8.95e-2)" 21.0 47.2 9.6 5.3 11.1 1.6 18.5 10.0 9.2 24.8 6.2 14.5 3.7 18.9 12.2 3.5 13.2 14.8 12.3 8.9 11.1 10.1 26.9 14.2 2.3 13.5 10.5 19.3 24.0 10.7 9.0 6.5 10.5 12.3 6.2 2.8 20.2 18.6 10.5 7.4 7.9 9.7 10.1 27.8 9.5 4.3 12.1 3.1 15.8 6.1 1.7 13.8 13.3 12.1 3.3 2.9 30.8 5.8 24.5 37.1 1.1 11.4 28.1 12.1 9.4 1.4 7.5 0.0 1.8 20.9 12.2 5.0 2.6 3.7 4.3 6.6 1.1 4.6 3.4 9.0 3.5 3.0 16.5 15.5 2.4 10.3 3.1 22.6 0.0 0.0 1.4 1.3 9.6 0.3 0.0 8.6 8.1 0.8 0.5 1.0 23.2 1.4 7.6 4.1 0.7 11.6 6.4 0.6 8.9 6.0 2.7 10.1 5.9 25.4 17.5 11.9 5.9 2.6 0.0 0.0 8.8 4.2 7.5 0.0 1.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 6.2 0.1 0.0 0.1 0.0 0.4 9.6 11.1 10.0 9.2 8.9 11.1 13.5 10.5 10.5 10.1 12.1 12.1 12.7 6.4 5.0 32.0 2.5 4.8 8.0 5.8 1.8 9.2 6.6 11.3 13.4 47.1 3.2 14.7 0.0 1.4 0.5 10.0 19.6 21.2 1.0 17.6 13.1 11.0 7.8 1.7 0.3 10.2 0.9 20.4 18.3 3.5 38.0 11.6 8.2 31.5 14.1 5.0 6.2 9.1 4.1 46.9 14.6 2.3 24.2 22.0 23.2 17.8 23.6 24.6 1.0 21.1 8.9 16.4 6.6 24.0 3.1 6.3 1.0 7.1 1.7 6.8 26.3 18.6 21.9 3.1 2.8 0.6 4.4 1.2 3.5 14.6 18.7 6.1 ARMC12 "C6orf81, FLJ25390" ENSG00000157343 "Armadillo repeat containing 12" Q5T9G4 6 35737032-35749079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 64.2" "Group enriched" "Detected in some" 96 "Early spermatids: 503.3;Late spermatids: 1116.3" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.9;HSkMC: 6.1;MOLT-4: 4.8;U-698: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030895, HPA075457, HPA075777" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Plasma membrane" "HPA030895: AB_10602114, HPA075457: , HPA075777: " "unprognostic (1.94e-4)" "unprognostic (2.21e-1)" "unprognostic (3.24e-1)" "unprognostic (1.32e-2)" "unprognostic (2.34e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.12e-1)" "unprognostic (4.48e-1)" "unprognostic (3.52e-2)" "unprognostic (6.36e-4)" "unprognostic (8.99e-2)" "unprognostic (1.17e-12)" "unprognostic (6.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (2.09e-1)" 1.6 1.7 4.4 0.6 4.4 0.9 1.5 4.0 5.3 2.5 5.1 1.5 0.0 1.7 5.8 0.8 2.8 0.7 0.7 4.3 4.5 1.5 4.5 1.2 1.3 4.6 5.1 3.0 1.3 0.5 11.2 0.2 4.6 3.6 0.3 1.3 0.6 0.8 1.9 1.1 1.7 0.7 4.3 2.8 1.2 64.2 4.3 3.0 2.4 0.5 0.7 1.1 1.7 4.5 0.0 0.3 2.1 2.7 4.9 2.3 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.5 0.1 0.1 0.8 0.1 0.6 0.1 0.1 1.2 0.6 0.3 0.1 0.0 2.4 0.0 0.0 6.1 1.5 0.1 0.9 2.5 0.5 2.0 0.0 3.2 0.8 0.3 4.8 0.6 0.4 0.0 0.1 2.2 0.0 0.0 0.5 0.0 0.6 2.0 0.0 0.0 0.4 1.0 1.4 0.2 0.0 0.4 0.2 0.1 0.0 0.7 0.2 5.4 0.2 2.8 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.2 0.9 0.0 0.0 0.0 0.8 0.0 0.1 4.4 4.4 4.0 5.3 4.3 4.5 4.6 5.1 4.6 4.3 4.3 4.5 0.8 0.0 0.0 4.6 0.1 0.9 1.9 0.2 1.2 0.0 0.3 0.4 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 503.3 0.4 0.4 0.8 0.0 0.4 0.3 0.0 0.0 0.6 0.0 0.3 0.0 2.4 0.4 2.8 0.0 0.0 0.5 0.2 0.0 1.2 0.8 1116.3 8.4 1.3 0.0 0.0 0.1 0.8 0.0 0.5 0.3 0.0 0.0 4.1 0.0 0.7 0.2 0.3 0.2 0.2 0.0 0.5 0.4 8.1 6.0 0.7 0.1 0.0 0.3 0.2 0.2 0.4 ARMCX3 "ALEX3, GASP6" ENSG00000102401 "Armadillo repeat containing X-linked 3" Q9UH62 X 101622797-101627843 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "thyroid cancer: 88.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000325, HPA000967, HPA001530" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA000325: AB_1078206, HPA000967: AB_1078208, HPA001530: AB_2666349" "unprognostic (1.67e-1)" "unprognostic (2.14e-1)" "unprognostic (5.23e-2)" "unprognostic (8.69e-3)" "unprognostic (1.73e-2)" "unprognostic (1.47e-2)" "unprognostic (9.72e-3)" "unprognostic (2.19e-2)" "unprognostic (4.77e-2)" "unprognostic (6.80e-2)" "unprognostic (3.38e-3)" "unprognostic (2.12e-2)" "prognostic favorable (1.55e-5)" "unprognostic (3.29e-2)" "unprognostic (3.13e-1)" "unprognostic (1.07e-2)" "unprognostic (1.55e-2)" 34.9 58.9 30.8 24.4 33.0 14.7 32.2 35.4 35.7 45.0 27.6 31.5 20.2 40.9 105.3 18.1 27.7 34.0 51.0 34.1 38.7 37.2 24.6 29.5 21.8 34.5 33.7 38.3 57.4 103.6 47.7 45.4 34.8 44.5 21.8 19.0 59.6 46.7 30.7 11.9 21.5 36.3 35.4 41.3 29.7 12.9 35.5 20.1 49.9 63.6 21.5 31.9 22.5 37.7 26.4 18.8 48.8 23.9 109.4 118.3 10.0 56.5 54.3 23.2 68.3 20.7 21.5 9.5 31.7 64.7 50.8 5.0 34.9 20.2 28.7 21.6 23.2 18.7 64.9 30.2 85.2 18.2 41.5 67.0 27.4 30.9 30.3 65.1 47.6 11.6 15.2 78.9 67.4 10.9 15.0 0.8 24.4 49.5 4.3 19.1 62.2 8.9 36.0 10.1 22.1 18.9 28.3 1.5 63.9 67.7 19.2 19.0 67.5 29.8 18.9 70.8 11.2 69.7 20.9 0.1 50.4 14.5 25.5 43.6 15.3 13.6 14.6 15.8 18.3 15.0 14.0 12.4 15.8 9.8 15.2 10.6 5.6 13.7 16.8 25.8 9.0 14.4 30.8 33.0 35.4 35.7 34.1 38.7 34.5 33.7 34.8 35.4 35.5 37.7 67.4 44.8 36.1 16.3 61.1 37.9 81.2 40.6 42.7 63.1 70.9 42.3 114.6 50.1 48.4 75.4 58.4 55.3 61.1 20.4 37.2 53.9 0.6 42.2 80.9 69.2 82.4 25.6 35.9 30.6 27.4 85.8 33.1 78.8 79.1 45.5 58.2 48.6 50.7 62.2 41.8 67.6 40.7 52.5 84.9 2.8 64.7 72.3 97.8 18.7 27.2 86.6 34.0 28.6 31.0 30.6 22.1 72.6 122.6 75.2 20.1 43.1 25.1 13.3 32.9 57.1 73.2 2.5 0.4 24.6 21.5 114.9 58.0 70.2 32.1 81.2 ARSK "DKFZp313G1735, TSULF" ENSG00000164291 "Arylsulfatase family member K" Q6UWY0 5 95555101-95605102 "Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 19.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042384 Approved Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles Nucleoplasm "HPA042384: AB_10795703" "unprognostic (9.50e-2)" "unprognostic (1.37e-1)" "unprognostic (2.03e-3)" "unprognostic (2.39e-1)" "unprognostic (3.33e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (2.59e-4)" "unprognostic (3.39e-1)" "unprognostic (1.37e-1)" "unprognostic (5.19e-2)" "unprognostic (7.61e-2)" "unprognostic (2.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.91e-2)" "unprognostic (2.32e-1)" "unprognostic (8.20e-2)" "unprognostic (1.06e-2)" 3.0 3.7 2.1 2.2 2.3 2.3 3.3 2.8 3.0 3.8 2.1 2.7 2.2 3.6 4.2 2.9 3.2 3.1 2.6 2.4 2.1 5.4 3.7 2.9 2.7 1.9 1.9 5.8 4.9 19.1 2.6 5.5 2.3 4.9 2.5 3.6 2.8 4.9 2.3 3.3 2.2 3.0 1.7 2.4 4.2 1.6 2.6 3.7 5.0 2.7 2.0 3.2 3.3 2.2 5.1 3.2 6.6 6.6 32.4 16.8 9.5 15.9 9.2 6.1 12.4 3.9 7.8 6.9 8.1 5.5 10.9 4.6 5.8 10.1 13.3 7.4 8.5 5.5 7.7 6.7 9.4 3.1 4.4 12.4 8.9 9.2 5.9 12.8 10.0 9.3 5.6 7.4 13.7 2.5 8.5 5.9 8.6 1.6 15.3 5.2 10.6 11.0 14.1 1.2 4.7 4.8 9.7 3.1 10.0 9.1 8.9 3.2 18.1 9.6 7.8 15.0 9.9 6.2 11.2 8.4 9.6 8.0 36.5 12.9 1.1 2.1 4.0 1.2 4.7 4.9 4.7 5.4 0.6 5.0 7.0 5.2 0.9 3.3 0.7 2.2 3.9 1.8 2.1 2.3 2.8 3.0 2.4 2.1 1.9 1.9 2.3 1.7 2.6 2.2 6.8 3.2 2.2 9.1 6.6 4.5 6.8 7.4 5.7 7.3 4.4 7.2 4.6 1.5 3.7 7.3 12.5 11.8 6.6 1.9 3.9 4.1 9.2 7.1 10.3 6.2 3.0 10.1 11.0 2.5 47.4 13.6 2.0 5.7 22.9 8.1 6.8 16.5 4.6 10.1 9.7 2.0 10.2 3.2 5.4 2.9 10.8 4.9 5.4 7.5 5.1 12.7 14.4 7.1 10.0 2.6 3.2 11.7 7.1 3.9 3.2 4.8 6.8 10.4 0.0 10.2 10.9 7.4 8.6 5.1 7.0 5.1 9.8 11.8 3.4 2.1 ASAP3 "CENTB6, DDEFL1, FLJ20199, UPLC1" ENSG00000088280 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 3" Q8TDY4 1 23428563-23484568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 35.9;Extravillous trophoblasts: 43.3;Granulosa cells: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 31.8;ASC TERT1: 29.9;HSkMC: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020537, HPA020546" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Vesicles Nucleoplasm "HPA020537: AB_2670467, HPA020546: AB_2670470" "unprognostic (2.51e-1)" "unprognostic (2.70e-2)" "unprognostic (4.35e-3)" "prognostic unfavorable (5.56e-4)" "unprognostic (3.87e-1)" "unprognostic (2.24e-2)" "unprognostic (1.19e-3)" "prognostic favorable (2.80e-4)" "unprognostic (1.88e-2)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.24e-1)" "unprognostic (1.18e-1)" "prognostic favorable (5.12e-5)" "unprognostic (3.39e-3)" "unprognostic (3.92e-2)" "unprognostic (2.02e-2)" "unprognostic (7.27e-2)" 24.1 39.1 11.5 3.2 11.6 0.1 21.9 12.5 12.4 32.6 10.0 18.4 1.6 18.6 4.2 32.3 24.3 5.1 30.1 10.5 11.2 21.4 19.8 15.9 1.6 14.5 12.7 58.3 22.2 11.7 18.6 8.0 13.2 31.0 5.2 3.0 38.0 8.0 42.9 52.9 11.0 5.9 12.7 5.0 25.4 18.2 13.4 1.0 29.0 11.7 4.2 21.3 33.4 12.1 1.8 1.8 17.6 11.6 31.8 29.9 21.6 3.2 3.8 4.9 6.3 1.3 0.1 9.2 3.7 6.3 2.9 8.4 12.2 2.9 2.8 0.4 1.6 0.5 4.8 11.8 17.1 0.0 0.9 38.4 4.4 7.9 7.1 14.6 3.9 1.3 6.4 0.0 3.1 3.9 1.3 0.1 3.0 5.0 4.2 4.9 1.9 0.0 3.4 3.7 0.6 6.0 14.1 3.5 3.5 8.7 13.2 0.1 1.4 2.1 5.2 5.9 0.2 3.9 4.2 1.1 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.5 11.6 12.5 12.4 10.5 11.2 14.5 12.7 13.2 12.7 13.4 12.1 4.5 9.6 6.7 35.9 0.3 2.0 1.5 2.0 2.8 1.1 6.3 3.7 15.5 0.0 4.1 3.7 0.0 2.1 0.0 6.7 3.9 5.8 5.1 2.4 7.3 6.6 1.2 0.0 7.6 6.1 43.3 12.2 10.2 4.4 1.3 28.3 3.9 4.0 1.8 0.0 4.9 8.5 2.0 0.0 1.3 8.1 12.5 0.4 0.0 7.5 0.1 8.3 0.0 18.1 4.2 2.5 2.1 13.5 0.2 2.4 0.8 5.4 4.3 0.6 0.0 2.0 3.4 8.2 11.8 3.7 4.3 1.4 0.2 15.9 5.2 2.1 ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503405 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;kidney: 38.2" "Cell type enhanced" "Detected in many" "Leydig cells: 49.7;Melanocytes: 46.2;Oligodendrocytes: 217.0;Peritubular cells: 48.2;Proximal enterocytes: 37.5;Proximal tubular cells: 74.8" "Cancer enhanced" "Detected in some" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 5.4;ASC TERT1: 4.1;CACO-2: 3.8;HSkMC: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA022142: AB_1845102, HPA022145: AB_1845103" "unprognostic (4.42e-2)" "unprognostic (4.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-3)" "unprognostic (4.36e-2)" "unprognostic (5.01e-1)" "unprognostic (1.08e-3)" "unprognostic (3.57e-1)" "unprognostic (4.17e-1)" "unprognostic (3.43e-1)" "unprognostic (5.27e-2)" "unprognostic (6.27e-2)" "unprognostic (1.25e-1)" "unprognostic (7.07e-4)" "unprognostic (2.77e-1)" "unprognostic (4.68e-1)" "unprognostic (1.49e-1)" 13.9 4.3 25.9 1.8 46.4 1.8 4.1 27.6 40.9 7.5 14.2 4.3 11.2 4.5 6.0 4.9 5.5 3.6 2.7 25.8 27.7 38.2 15.0 3.5 1.5 30.4 35.4 2.9 1.0 0.8 0.8 3.5 29.5 4.1 4.9 2.8 1.8 5.0 11.9 5.2 15.6 3.1 24.7 5.4 4.4 6.6 42.4 0.6 2.1 15.0 0.7 6.3 4.3 69.0 0.2 0.1 0.5 0.5 5.4 4.1 0.3 0.2 0.1 0.2 0.1 3.8 0.2 0.6 0.2 0.7 0.3 0.3 0.3 0.1 0.2 2.0 0.1 0.4 0.7 0.2 0.5 0.4 0.4 7.5 0.3 0.4 0.1 0.1 0.1 0.4 0.3 1.1 0.2 0.2 0.2 0.6 0.4 0.2 0.3 0.3 0.3 0.6 0.2 1.1 0.4 0.3 1.1 0.3 0.9 0.4 0.3 0.2 0.4 0.6 0.4 0.4 0.3 0.7 0.4 0.4 0.2 0.4 0.5 1.1 0.1 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.2 0.7 0.3 0.1 0.2 0.1 0.0 25.9 46.4 27.6 40.9 25.8 27.7 30.4 35.4 29.5 24.7 42.4 69.0 5.1 9.6 1.5 12.1 0.1 5.2 1.5 1.6 6.2 5.5 2.1 0.8 1.3 2.8 1.0 25.8 0.0 0.0 0.0 0.3 7.9 0.2 5.0 0.1 4.1 1.1 2.4 2.7 0.6 0.2 0.1 15.0 2.0 0.2 0.0 0.1 3.9 11.5 0.2 8.4 0.4 0.8 2.0 0.8 1.5 2.5 49.7 0.8 46.2 3.7 0.0 4.1 0.0 1.5 217.0 0.0 2.5 48.2 0.2 0.4 37.5 74.8 0.1 0.5 0.0 8.5 11.6 11.1 0.6 0.7 1.7 0.1 0.4 28.3 1.8 2.7 ASPN "FLJ20129, PLAP-1, SLRR1C" ENSG00000106819 Asporin Q9BXN1 9 92456205-92482506 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 95.3;smooth muscle: 110.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 67.2;Fibroblasts: 94.6;Microglial cells: 24.4;Sertoli cells: 39.5;Smooth muscle cells: 73.5;Suprabasal keratinocytes: 27.0" "Cancer enhanced" "Detected in all" "breast cancer: 51.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enhanced" "Detected in single" "granulocytes: 2.4" "Cell line enhanced" "Detected in some" "ASC TERT1: 16.0;BJ hTERT+: 5.7;HHSteC: 23.2;HSkMC: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007894, HPA008435, HPA024230" Approved Uncertain Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 2100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA007894: , HPA008435: AB_1845112, HPA024230: AB_1845113" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (8.13e-3)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.01e-2)" "unprognostic (9.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-3)" "unprognostic (6.38e-2)" "unprognostic (3.70e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (1.64e-7)" "unprognostic (1.42e-3)" "unprognostic (3.04e-2)" "unprognostic (6.27e-3)" "unprognostic (2.48e-2)" 29.6 7.6 1.2 5.7 1.7 0.1 11.8 2.3 2.0 40.9 0.9 25.5 9.6 69.6 9.7 10.1 16.9 65.9 95.3 1.2 1.2 11.2 41.1 14.3 3.0 1.3 1.2 7.1 13.4 3.8 2.5 4.3 1.6 4.7 11.3 0.2 3.2 11.7 7.8 12.1 17.6 110.5 1.0 2.3 12.0 1.2 1.8 2.5 11.1 19.8 5.5 13.4 5.0 1.7 0.1 0.0 0.0 0.0 1.4 16.0 0.2 2.6 5.7 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 23.2 0.2 0.0 4.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 1.2 1.7 2.3 2.0 1.2 1.2 1.3 1.2 1.6 1.0 1.8 1.7 12.9 0.0 1.1 0.3 0.1 67.2 0.1 0.0 0.0 0.4 0.4 0.1 8.5 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 4.2 6.8 0.0 0.0 2.0 0.0 0.1 94.6 0.5 0.2 1.3 0.1 13.9 0.4 0.2 0.0 1.7 0.0 0.0 0.0 13.5 0.6 5.9 0.8 14.2 24.4 0.0 0.1 0.0 1.5 1.1 0.0 0.0 1.9 0.3 0.0 0.0 0.0 0.7 0.6 39.5 4.3 73.5 0.0 0.1 0.3 27.0 0.0 1.7 0.3 0.0 0.0 ATG2B "C14orf103, FLJ10242" ENSG00000066739 "Autophagy related 2B" Q96BY7 14 96279195-96363341 "Predicted intracellular proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 84.5;Oligodendrocyte precursor cells: 105.6;Oligodendrocytes: 84.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001427, HPA019665" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "HPA001427: AB_1845551, HPA019665: AB_2274278" "unprognostic (9.39e-2)" "unprognostic (1.01e-1)" "unprognostic (7.28e-2)" "unprognostic (1.07e-1)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (3.19e-1)" "unprognostic (9.29e-3)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-3)" "unprognostic (1.45e-2)" "unprognostic (7.60e-3)" "unprognostic (6.66e-2)" "unprognostic (3.08e-1)" "unprognostic (3.90e-2)" "unprognostic (8.49e-2)" 6.4 6.2 5.8 3.9 6.8 6.7 6.5 8.6 7.9 7.2 5.8 6.3 4.4 7.4 5.5 5.2 6.9 4.2 4.9 6.2 5.4 5.6 9.8 6.0 4.7 8.1 5.4 7.2 12.1 8.2 6.8 4.0 8.2 5.9 4.3 12.1 5.4 4.0 8.6 11.4 7.3 5.0 5.0 6.4 6.4 8.6 5.9 6.9 7.3 7.2 4.9 5.7 6.3 9.0 3.8 4.8 5.8 4.5 9.9 9.1 4.6 5.5 7.8 5.9 6.7 2.6 2.6 8.5 5.1 9.1 3.9 5.1 8.0 5.4 9.5 7.9 4.0 3.7 5.2 2.3 6.5 6.9 3.9 7.6 5.4 8.0 6.3 6.3 7.6 6.3 4.3 7.5 4.8 6.2 6.2 5.9 2.8 4.5 4.8 5.6 13.0 5.7 6.7 4.6 5.6 6.4 8.4 3.4 4.0 5.9 5.3 3.9 10.2 3.3 1.5 8.1 3.5 7.4 6.5 7.7 6.7 4.7 3.2 0.1 0.2 0.4 0.3 0.1 0.5 0.2 0.3 0.3 0.2 0.2 0.3 0.3 0.4 0.5 0.2 0.3 0.5 0.1 5.8 6.8 8.6 7.9 6.2 5.4 8.1 5.4 8.2 5.0 5.9 9.0 15.8 12.8 12.3 47.3 11.0 13.8 3.7 4.4 21.6 24.8 12.2 7.7 14.2 12.8 6.3 9.2 27.1 5.8 12.3 9.5 3.9 5.8 41.0 20.8 16.9 12.9 8.3 21.8 84.5 6.1 3.2 14.0 10.7 26.9 7.0 10.9 14.6 27.2 4.2 32.0 66.3 13.3 2.0 12.6 10.7 48.9 12.8 8.9 1.8 36.5 6.4 7.9 6.2 105.6 84.2 5.3 10.7 10.5 27.2 9.0 12.5 8.9 7.0 19.4 6.6 13.8 12.6 17.7 14.9 19.6 28.1 15.7 13.0 8.7 9.4 3.7 ATP6AP2 "APT6M8-9, ATP6IP2, ATP6M8-9, M8-9, PRR, RENR" ENSG00000182220 "ATPase H+ transporting accessory protein 2" O75787 X 40579372-40606848 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Congenital disorder of glycosylation, Disease variant, Epilepsy, Mental retardation, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 765.1" "Cell type enhanced" "Detected in all" "Hofbauer cells: 702.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003156 Approved NA NA 140000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA003156: AB_1078245" "unprognostic (1.45e-1)" "unprognostic (3.80e-3)" "unprognostic (1.30e-1)" "unprognostic (7.19e-2)" "unprognostic (8.58e-3)" "unprognostic (1.29e-1)" "unprognostic (1.63e-3)" "unprognostic (2.01e-2)" "unprognostic (1.00e-1)" "unprognostic (4.15e-2)" "unprognostic (1.45e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.01e-5)" "unprognostic (2.34e-1)" "unprognostic (2.08e-1)" "unprognostic (1.62e-2)" "unprognostic (2.86e-2)" 81.2 71.5 85.6 60.6 86.5 124.4 95.1 76.4 116.9 106.1 72.4 82.9 32.1 86.6 91.3 70.1 75.6 79.7 55.1 90.8 90.2 165.6 96.8 87.3 67.4 80.4 79.8 68.9 53.3 765.1 30.7 106.9 83.4 86.6 89.0 99.3 39.4 97.9 18.4 71.9 47.8 124.7 84.6 69.0 49.1 40.4 87.6 72.0 177.1 40.1 72.5 97.7 41.4 98.7 83.9 117.5 78.7 106.7 472.6 312.4 47.9 182.4 274.1 127.0 152.9 68.0 142.6 48.4 88.1 257.0 141.3 86.6 114.0 136.0 168.2 92.7 97.7 57.5 100.2 66.5 172.0 104.6 111.6 259.6 175.2 154.2 121.4 200.3 168.1 46.1 63.8 130.7 201.7 109.8 45.5 93.7 73.4 140.8 112.7 43.8 132.6 161.6 182.8 96.8 55.2 51.9 185.8 111.7 118.4 284.2 147.8 97.1 172.5 175.0 91.3 207.7 62.8 38.0 70.7 46.2 139.1 93.0 138.5 269.0 511.1 404.8 156.1 364.9 164.3 106.7 157.3 161.9 341.3 110.3 174.8 159.3 255.9 141.2 378.6 124.2 167.2 692.9 85.6 86.5 76.4 116.9 90.8 90.2 80.4 79.8 83.4 84.6 87.6 98.7 102.3 57.7 65.6 36.2 65.4 97.3 135.4 254.3 46.1 155.8 74.1 61.2 30.4 94.4 175.4 138.0 54.2 173.4 109.6 70.3 62.6 146.6 3.6 97.2 115.5 94.7 57.1 62.3 44.8 59.1 106.3 156.5 34.7 124.5 87.5 63.7 96.0 64.0 702.2 188.4 56.3 54.6 349.9 279.5 263.3 9.5 117.4 222.0 149.4 28.1 185.4 193.0 72.1 40.2 40.6 64.0 58.9 151.2 74.8 97.9 61.0 106.4 127.4 93.3 105.2 116.7 138.7 106.7 43.1 60.0 99.9 174.4 100.3 188.2 63.6 121.1 ATP8B2 "ATPID, KIAA1137" ENSG00000143515 "ATPase phospholipid transporting 8B2" P98198 1 154325525-154351304 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 26.8;Excitatory neurons: 28.5;Inhibitory neurons: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 2.8;T-cells: 3.7" "Cell line enhanced" "Detected in many" "ASC diff: 120.9;fHDF/TERT166: 112.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046680, HPA061103" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" "Nucleoli, Cytosol" "HPA046680: AB_2679749, HPA061103: " "unprognostic (1.68e-1)" "unprognostic (3.68e-1)" "unprognostic (8.40e-2)" "unprognostic (5.16e-2)" "unprognostic (4.52e-1)" "unprognostic (8.17e-2)" "unprognostic (2.27e-2)" "unprognostic (6.93e-3)" "unprognostic (2.57e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.60e-4)" "unprognostic (2.82e-1)" "unprognostic (1.89e-3)" "unprognostic (7.77e-3)" "unprognostic (6.58e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (5.29e-5)" 17.2 9.5 8.2 22.7 7.8 5.4 14.0 18.8 11.0 28.7 20.7 17.8 12.5 39.2 17.7 11.0 30.8 18.2 15.2 10.8 9.2 6.3 3.4 18.0 25.4 8.9 8.1 35.3 5.9 10.5 19.3 15.3 9.6 18.9 9.1 2.1 7.2 21.2 3.5 8.5 17.6 39.7 5.6 19.5 14.5 16.3 8.8 18.4 15.0 7.4 19.6 19.7 17.9 7.7 2.1 15.6 20.0 20.5 120.9 80.4 0.3 41.8 77.4 26.1 30.5 0.3 0.6 1.9 21.4 112.4 17.7 9.2 23.0 5.5 19.3 46.6 16.8 19.7 20.4 18.9 37.2 0.1 14.8 53.4 1.3 40.6 38.7 35.6 40.0 25.1 37.6 47.8 22.7 21.8 36.2 2.5 43.7 0.4 17.4 39.9 12.7 71.5 5.3 0.4 17.4 22.7 11.3 2.8 30.3 28.3 14.9 15.3 34.7 40.2 19.2 51.4 13.5 58.0 75.7 11.1 14.1 2.2 24.7 2.8 0.0 1.7 1.1 0.0 0.7 0.3 1.7 1.9 0.0 0.2 1.4 1.2 0.0 0.5 0.0 0.3 3.7 0.5 8.2 7.8 18.8 11.0 10.8 9.2 8.9 8.1 9.6 5.6 8.8 7.7 6.4 3.2 4.5 26.8 7.7 2.5 1.4 0.9 0.0 4.5 1.9 2.3 6.2 0.0 1.9 0.0 2.1 0.1 16.0 0.1 0.0 1.6 0.6 6.5 20.5 9.0 0.0 0.4 28.5 0.2 0.5 12.8 0.5 2.4 7.6 10.8 13.6 0.8 0.4 8.4 31.7 0.2 0.0 1.0 4.2 1.4 11.5 1.3 7.2 4.7 0.9 3.4 7.2 4.0 4.2 0.9 0.0 14.7 13.9 5.6 0.0 0.2 4.4 0.5 0.0 9.5 11.2 2.6 4.3 0.6 1.6 0.3 17.2 6.7 0.1 0.8 ATRAID "APR3, C2orf28, HSPC013, p18" ENSG00000138085 "All-trans retinoic acid induced differentiation factor" Q6UW56 2 27212027-27217178 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051353 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA051353: AB_2681451" "unprognostic (4.58e-2)" "unprognostic (9.41e-3)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (3.85e-2)" "unprognostic (4.41e-2)" "unprognostic (1.59e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (5.73e-2)" "unprognostic (5.35e-3)" "unprognostic (2.36e-2)" "unprognostic (4.86e-2)" "unprognostic (1.77e-1)" "unprognostic (3.76e-1)" "unprognostic (1.92e-1)" 86.5 79.6 57.3 48.0 62.2 72.2 109.9 62.7 70.8 108.8 73.8 82.0 59.8 82.1 343.6 59.1 123.7 68.0 129.7 56.9 61.8 133.2 72.0 74.8 63.8 64.5 60.1 119.6 120.2 120.5 40.7 74.8 64.2 81.5 92.3 56.7 107.7 107.3 142.6 55.9 59.4 72.7 61.7 64.4 73.3 96.1 59.3 68.4 114.1 139.1 66.2 79.2 38.1 66.4 126.9 145.6 82.4 144.9 408.7 242.2 126.9 75.6 227.6 93.8 87.0 116.2 184.4 63.5 126.6 201.3 134.8 108.7 75.9 132.2 81.1 101.2 77.2 75.0 79.4 182.6 185.9 65.2 93.6 192.5 275.5 80.2 179.3 213.3 123.7 110.5 76.4 191.7 144.5 161.8 78.8 174.0 124.0 263.3 123.0 70.5 218.7 293.2 161.2 68.6 90.7 136.5 89.7 112.4 122.8 118.4 96.3 98.5 82.8 147.9 87.4 54.1 77.8 302.4 249.6 166.2 152.9 124.8 143.5 188.4 242.1 206.7 198.5 223.2 202.9 278.5 227.6 226.9 251.1 271.1 238.8 219.6 54.1 189.1 240.7 293.2 277.5 443.1 57.3 62.2 62.7 70.8 56.9 61.8 64.5 60.1 64.2 61.7 59.3 66.4 143.0 60.9 82.1 7.8 96.4 102.2 176.4 306.4 112.1 44.2 135.0 155.7 163.2 114.4 169.9 143.5 18.8 273.0 95.0 68.6 181.9 182.5 159.6 113.7 109.5 118.4 91.8 47.1 4.3 191.3 328.2 200.0 57.6 96.8 90.7 124.6 113.2 82.7 209.4 28.6 6.6 134.6 205.4 110.7 104.8 223.9 196.3 100.9 176.1 9.4 157.6 153.9 92.7 9.5 13.9 126.1 123.1 141.1 177.0 109.6 135.1 212.0 160.8 48.9 52.6 103.8 137.8 374.7 162.6 110.2 100.7 250.5 93.5 167.8 137.6 153.7 BACE1 BACE ENSG00000186318 "Beta-secretase 1" P56817 11 117285207-117316259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 119.1;pancreas: 271.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 118.9;Early spermatids: 99.9;Late spermatids: 343.0;Oligodendrocytes: 99.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 88.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016358 Approved Supported "Plasma membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "CAB016358: AB_626716" "unprognostic (7.96e-3)" "unprognostic (8.05e-2)" "unprognostic (3.55e-2)" "unprognostic (3.05e-3)" "unprognostic (8.94e-2)" "unprognostic (3.39e-1)" "unprognostic (1.03e-1)" "unprognostic (2.60e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (8.09e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.35e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.76e-4)" 15.4 16.0 34.3 8.0 68.5 3.3 11.7 68.7 44.0 18.3 11.9 13.7 6.1 19.7 8.8 13.5 15.9 19.1 11.4 34.3 44.5 14.8 25.6 14.4 5.1 89.7 67.0 20.5 271.5 18.5 10.7 13.8 76.6 13.4 7.6 44.7 11.0 18.3 12.5 11.4 7.7 21.3 61.6 12.4 9.8 11.2 59.9 3.8 12.2 9.1 5.0 12.4 14.3 119.1 11.5 10.7 22.9 37.3 80.9 82.3 1.0 62.9 44.4 24.4 19.0 4.5 16.4 1.4 14.6 88.3 18.4 17.9 24.3 12.1 20.5 3.1 12.1 6.0 17.3 5.1 36.5 2.5 1.7 68.1 20.2 29.7 31.8 68.0 21.4 3.8 2.7 1.1 46.5 33.4 2.5 2.1 15.5 10.6 25.9 6.4 11.6 1.6 12.2 5.9 31.7 36.7 22.5 2.6 5.9 23.5 26.2 7.6 31.4 45.2 5.0 48.2 19.4 0.7 1.0 1.1 23.8 2.0 34.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 34.3 68.5 68.7 44.0 34.3 44.5 89.7 67.0 76.6 61.6 59.9 119.1 12.1 19.2 10.1 16.3 0.3 4.7 4.1 3.4 9.1 53.7 8.7 9.0 8.7 18.6 13.3 5.5 118.9 1.0 0.1 2.0 5.9 7.4 99.9 5.1 32.1 8.3 21.7 1.7 24.9 20.0 1.3 19.5 3.1 8.9 2.5 15.8 6.8 38.6 9.4 57.2 32.0 5.1 2.0 17.2 7.7 343.0 19.3 7.9 3.6 14.0 4.0 17.9 0.0 22.1 99.8 4.3 6.3 22.2 0.1 2.4 1.7 6.3 3.4 55.2 6.6 18.1 14.2 3.4 1.7 10.6 3.4 0.8 1.2 68.0 4.5 3.4 BBS1 FLJ23590 ENSG00000174483 "Bardet-Biedl syndrome 1" Q8NFJ9 11 66510606-66533613 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Olfaction, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 19.9;Excitatory neurons: 28.5;Inhibitory neurons: 28.4;Microglial cells: 14.0;Oligodendrocyte precursor cells: 13.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA058283 Uncertain Uncertain Midbody Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Midbody "HPA058283: AB_2683667" "unprognostic (1.06e-1)" "unprognostic (1.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.14e-1)" "unprognostic (1.56e-1)" "unprognostic (1.08e-3)" "unprognostic (1.40e-2)" "unprognostic (6.68e-2)" "unprognostic (1.72e-2)" "unprognostic (2.76e-1)" "unprognostic (1.19e-3)" "unprognostic (2.61e-2)" "unprognostic (6.05e-2)" "unprognostic (3.04e-1)" "unprognostic (2.20e-1)" "unprognostic (2.38e-1)" "unprognostic (4.87e-4)" 10.5 15.2 11.5 4.9 13.0 2.9 11.9 10.8 17.8 18.9 13.9 18.0 6.5 20.7 17.7 9.0 28.0 12.6 10.1 11.6 12.7 24.2 7.0 10.4 5.1 10.2 13.5 27.5 13.5 38.0 17.9 8.2 10.1 15.8 7.3 21.4 16.8 22.0 8.1 9.6 9.4 14.1 10.5 6.0 13.8 10.5 13.3 8.0 27.1 8.2 5.0 15.4 10.9 10.7 5.7 6.0 13.7 5.4 24.9 17.2 6.3 4.8 9.6 6.3 6.0 9.5 10.1 0.8 10.0 11.5 5.6 10.6 10.1 10.6 6.8 5.2 5.8 2.5 8.9 5.3 11.7 4.7 1.8 17.7 9.7 9.7 7.1 17.8 8.9 8.5 5.5 4.3 7.8 5.1 3.7 4.1 10.4 18.0 10.5 9.2 9.0 7.4 19.3 6.4 14.0 9.3 8.1 8.7 18.6 6.6 18.7 2.5 8.7 5.0 5.7 6.0 1.6 3.1 1.5 1.4 16.3 1.3 5.4 0.0 1.5 0.2 1.8 1.6 2.6 2.2 2.5 2.0 1.2 1.1 1.7 2.2 0.9 3.1 3.0 0.5 0.8 1.9 11.5 13.0 10.8 17.8 11.6 12.7 10.2 13.5 10.1 10.5 13.3 10.7 0.5 0.0 2.2 19.9 2.5 0.5 1.3 1.6 0.6 3.9 0.9 1.0 0.5 1.5 1.1 0.0 8.4 1.6 0.5 0.6 0.0 0.8 4.1 2.3 1.8 1.3 1.2 3.0 28.5 0.4 0.6 3.1 7.1 0.9 0.0 2.9 0.7 0.3 0.6 0.0 28.4 0.7 2.0 0.9 0.7 2.6 0.9 0.5 0.0 14.0 0.8 1.7 1.0 13.6 9.0 0.4 0.5 1.5 2.5 0.8 0.4 1.7 9.2 10.8 0.0 1.5 1.6 4.9 2.6 2.2 1.0 1.0 1.4 2.0 0.9 0.9 BBS7 "BBS2L1, FLJ10715" ENSG00000138686 "Bardet-Biedl syndrome 7" Q8IWZ6 4 121824329-121870487 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "retina: 56.6" "Cell type enhanced" "Detected in all" "Excitatory neurons: 65.1;Inhibitory neurons: 58.6;Rod photoreceptor cells: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044592 Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA044592: AB_10795882" "unprognostic (6.36e-2)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (1.85e-1)" "unprognostic (1.10e-2)" "unprognostic (1.89e-1)" "unprognostic (3.15e-5)" "unprognostic (6.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.48e-1)" "unprognostic (1.49e-1)" "unprognostic (9.10e-3)" "unprognostic (2.67e-2)" "unprognostic (1.62e-1)" "unprognostic (4.22e-2)" "unprognostic (1.41e-1)" "unprognostic (4.33e-1)" 6.9 6.4 7.3 5.3 7.7 2.1 6.1 9.8 12.4 7.9 2.6 6.3 5.0 10.5 4.9 6.2 7.9 5.9 4.7 7.7 6.4 6.7 2.4 5.3 5.0 8.9 7.8 12.4 3.7 9.1 9.1 4.7 8.7 6.8 6.3 56.6 4.8 6.6 3.8 6.8 5.3 10.3 5.1 4.6 4.8 9.1 8.4 6.4 5.5 5.5 4.8 5.8 6.9 8.9 13.7 6.6 14.9 10.9 18.8 27.2 5.4 18.3 14.6 15.5 14.2 5.2 7.4 15.0 5.1 21.7 11.6 7.1 15.5 14.8 17.6 14.4 12.1 8.9 10.0 6.2 16.7 12.7 8.0 14.0 10.6 17.7 13.3 20.2 16.8 10.0 6.0 14.8 22.1 4.3 21.3 6.1 7.9 8.3 8.2 9.7 19.3 4.6 15.7 4.8 16.4 7.0 17.5 7.7 14.0 19.7 6.5 4.7 16.9 11.6 12.5 16.2 11.8 13.9 10.3 13.1 13.4 10.0 11.6 0.6 1.0 1.7 1.9 1.1 1.5 0.9 1.5 1.8 1.2 0.9 1.2 1.6 0.2 2.0 1.2 1.2 1.6 1.0 7.3 7.7 9.8 12.4 7.7 6.4 8.9 7.8 8.7 5.1 8.4 8.9 15.7 6.4 8.4 12.7 6.9 8.7 10.8 13.7 5.7 16.6 6.0 9.3 8.4 4.3 13.0 11.0 47.9 8.5 6.6 6.4 13.7 14.6 22.2 14.4 19.9 11.2 6.1 9.5 65.1 9.8 21.5 14.4 6.1 10.6 15.2 9.2 8.6 5.0 11.4 16.8 58.6 8.2 16.2 6.3 6.1 12.9 13.1 7.7 8.8 16.9 6.3 12.6 5.2 30.7 26.4 15.6 5.1 11.3 5.6 9.3 6.0 15.1 16.5 68.9 19.7 12.2 15.2 39.6 22.4 10.9 8.5 5.7 10.7 11.4 8.4 8.6 BBS9 "B1, PTHB1" ENSG00000122507 "Bardet-Biedl syndrome 9" Q3SYG4 7 33109557-33877180 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 125.7;Excitatory neurons: 162.6;Inhibitory neurons: 159.0;Microglial cells: 266.1;Oligodendrocyte precursor cells: 238.8;Oligodendrocytes: 366.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021289 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA021289: AB_1845286" "unprognostic (1.18e-1)" "unprognostic (2.18e-1)" "unprognostic (3.13e-1)" "unprognostic (3.17e-1)" "unprognostic (4.86e-1)" "unprognostic (2.34e-1)" "unprognostic (1.19e-3)" "unprognostic (2.27e-1)" "unprognostic (8.68e-2)" "unprognostic (4.13e-2)" "unprognostic (7.22e-3)" "unprognostic (1.38e-1)" "prognostic favorable (1.86e-4)" "unprognostic (2.75e-2)" "unprognostic (1.28e-1)" "unprognostic (5.20e-1)" "unprognostic (6.90e-3)" 6.9 8.0 9.1 2.5 10.7 1.9 6.7 8.8 8.6 10.8 13.7 6.3 0.7 5.8 4.2 4.7 6.9 3.8 6.4 7.9 8.5 6.8 4.3 5.8 3.4 9.9 9.8 9.5 3.9 10.4 13.2 4.5 10.0 6.9 3.0 21.9 6.3 5.7 3.5 5.5 4.1 4.4 9.5 4.8 4.4 9.9 10.6 5.5 11.4 3.6 3.0 6.2 8.5 10.6 3.1 3.2 6.0 6.4 12.1 11.0 2.7 3.7 11.7 3.4 10.1 2.7 5.2 4.7 4.4 8.5 9.6 3.9 3.1 7.0 8.3 2.3 4.8 0.9 5.6 3.2 5.3 1.4 2.1 10.1 3.8 6.6 2.6 10.5 8.8 9.9 2.8 5.5 7.3 2.9 3.0 2.5 3.3 4.6 4.4 3.6 2.0 2.7 4.4 1.4 2.7 5.2 7.6 3.3 6.6 8.8 8.0 0.8 4.0 3.3 4.9 6.9 2.3 6.8 10.3 6.6 8.7 2.3 5.4 4.9 2.9 4.5 4.9 4.6 5.5 4.4 4.5 5.3 2.4 4.4 4.3 5.4 1.1 7.4 2.3 0.9 5.6 2.9 9.1 10.7 8.8 8.6 7.9 8.5 9.9 9.8 10.0 9.5 10.6 10.6 7.3 3.2 3.7 125.7 6.9 3.7 6.7 3.1 7.4 6.8 3.6 3.4 14.2 2.8 5.0 5.5 29.2 3.6 4.3 1.8 3.9 3.7 28.6 17.6 7.2 7.4 3.6 3.8 162.6 1.5 4.6 7.3 5.1 3.6 0.0 5.9 5.3 2.5 3.7 5.0 159.0 2.7 8.2 2.5 2.9 6.6 4.1 3.4 1.8 266.1 2.2 7.8 4.1 238.8 366.6 1.5 0.5 5.7 8.1 1.6 1.8 3.8 15.6 51.2 0.0 6.0 5.5 25.6 14.7 6.0 3.3 2.5 7.1 4.6 2.3 4.3 BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 41.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.3;Endothelial cells: 18.2;Fibroblasts: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 49.2;BJ hTERT+: 94.5;U-87 MG: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA003551, HPA050841" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA003551: , HPA050841: AB_2681254" "unprognostic (1.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (8.79e-3)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-3)" "unprognostic (3.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" 14.0 1.4 0.8 5.5 1.0 0.0 5.8 3.8 1.1 15.6 0.9 12.4 7.9 6.7 2.4 17.2 7.2 20.8 1.2 0.9 0.8 13.4 0.7 2.5 0.3 4.9 1.3 1.0 9.4 0.9 0.8 1.3 5.0 4.8 12.2 0.0 3.5 6.2 0.9 5.4 9.7 10.2 1.0 0.1 4.9 0.2 1.5 0.9 3.6 1.8 1.7 41.1 15.4 1.2 1.7 6.1 0.1 11.0 16.2 49.2 0.0 5.5 94.5 3.2 3.7 0.3 10.4 0.0 0.2 8.7 3.7 14.8 0.0 2.4 2.8 1.2 0.1 0.0 1.1 0.0 7.8 0.0 0.0 15.1 7.5 9.4 4.7 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.1 0.1 20.4 0.0 0.0 2.2 0.0 3.2 0.0 3.4 1.1 1.8 15.6 0.1 2.1 1.0 0.0 0.0 0.3 0.3 3.3 0.1 0.2 0.0 0.0 39.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 1.0 3.8 1.1 0.9 0.8 4.9 1.3 5.0 1.0 1.5 1.2 8.2 3.2 3.1 0.0 0.0 9.2 0.7 5.3 6.8 0.0 0.2 0.5 0.6 10.0 11.6 9.2 0.0 1.2 0.0 19.3 7.9 11.5 0.0 7.5 16.1 18.2 7.1 0.0 1.8 3.8 3.6 25.8 1.1 4.6 0.0 0.0 3.3 0.2 0.2 0.0 0.4 7.2 8.2 0.0 15.2 0.0 0.9 0.4 5.4 0.0 0.0 0.0 0.0 1.0 1.9 6.9 6.2 1.2 0.0 1.0 10.6 0.2 12.5 0.0 0.0 4.5 1.2 0.0 0.0 15.3 5.8 4.0 0.3 0.1 0.9 2.9 BORCS7 "C10orf32, FLJ40752" ENSG00000166275 "BLOC-1 related complex subunit 7" Q96B45 10 102854259-102864961 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 201.5;Proximal tubular cells: 208.5;Theca cells: 209.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA037648 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" Cytosol "HPA037648: AB_10673634" "unprognostic (2.16e-1)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (1.01e-2)" "unprognostic (2.05e-1)" "unprognostic (1.32e-1)" "unprognostic (1.09e-3)" "unprognostic (3.55e-2)" "unprognostic (1.35e-2)" "unprognostic (7.46e-3)" "unprognostic (3.16e-2)" "unprognostic (1.77e-1)" "prognostic favorable (9.08e-8)" "unprognostic (9.85e-2)" "unprognostic (1.77e-1)" "unprognostic (1.06e-1)" "unprognostic (1.67e-3)" 25.4 58.5 20.5 12.8 20.9 23.4 29.8 20.3 25.1 21.3 22.3 19.7 23.2 21.8 23.7 13.4 29.7 22.4 22.3 21.5 23.1 39.8 67.0 23.8 15.1 21.2 21.7 21.8 17.5 53.3 23.7 21.7 21.3 27.2 15.2 20.2 16.9 17.4 28.6 13.9 19.5 16.7 22.5 24.4 20.9 20.2 22.7 14.6 55.3 25.9 12.3 17.4 16.0 23.0 14.9 19.8 23.4 20.7 25.6 35.1 19.5 21.6 44.1 16.3 15.5 13.3 16.6 9.4 11.1 34.6 17.1 12.2 7.9 11.1 12.0 12.1 16.7 21.7 12.5 27.7 29.5 39.4 35.9 44.1 29.8 11.0 17.4 34.0 28.9 13.2 13.0 9.7 26.4 10.9 11.0 16.2 7.9 20.3 18.4 19.8 31.4 13.8 13.6 16.1 6.6 25.5 8.0 14.2 34.7 10.4 27.0 22.2 21.6 13.7 14.6 14.1 15.3 24.9 40.8 11.1 29.0 22.7 5.0 31.3 30.1 22.9 17.3 35.0 19.4 26.5 17.9 18.0 22.1 23.2 19.8 18.4 9.6 27.7 32.9 47.1 19.7 15.1 20.5 20.9 20.3 25.1 21.5 23.1 21.2 21.7 21.3 22.5 22.7 23.0 85.2 54.5 79.6 0.0 49.1 0.0 61.0 0.0 45.5 50.9 94.5 62.9 0.0 48.6 32.2 42.3 39.6 89.6 57.4 18.0 201.5 35.3 21.1 61.1 38.8 67.3 34.0 18.3 0.0 33.3 39.2 60.4 39.8 31.9 34.1 44.2 68.2 74.9 51.7 63.9 0.0 33.4 0.0 49.8 0.0 22.8 42.3 54.1 0.0 0.0 52.1 109.8 53.5 0.0 0.0 28.5 48.5 62.1 28.6 53.8 70.1 208.5 43.7 50.6 39.5 53.3 44.0 80.1 52.4 44.7 0.0 121.5 39.8 209.5 41.0 54.5 BTN3A3 "BTF3, BTN3.3" ENSG00000111801 "Butyrophilin subfamily 3 member A3" O00478 6 26440472-26453415 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 26.9;NK-cells: 33.0;Plasma cells: 30.5;T-cells: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 62.8;BJ hTERT+ SV40 Large T+ RasG12V: 43.8" "HPA007904, HPA011871" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "HPA007904: AB_1078307, HPA011871: AB_1845496" "unprognostic (1.18e-2)" "unprognostic (6.54e-3)" "unprognostic (1.54e-1)" "unprognostic (1.19e-2)" "unprognostic (2.30e-2)" "unprognostic (8.60e-2)" "unprognostic (5.13e-3)" "unprognostic (8.08e-2)" "unprognostic (7.88e-2)" "prognostic favorable (1.80e-4)" "unprognostic (4.45e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.42e-5)" "unprognostic (3.49e-2)" "unprognostic (2.14e-2)" "unprognostic (5.26e-2)" "unprognostic (4.54e-3)" 14.9 19.6 7.4 20.0 7.0 5.5 12.0 6.5 7.9 16.6 8.0 15.0 17.5 16.7 18.7 8.3 20.3 20.3 9.0 7.2 9.0 8.9 20.6 33.7 29.2 10.0 7.2 19.5 4.8 5.0 12.2 10.2 7.6 9.4 14.6 1.8 12.3 11.2 5.8 11.6 16.7 17.1 9.0 47.2 16.3 3.3 7.5 21.5 9.2 14.4 22.8 16.7 9.5 8.2 4.1 1.8 1.8 1.6 33.2 62.8 0.5 5.4 29.7 12.0 43.8 0.0 12.3 25.0 24.5 9.0 11.1 2.9 2.6 9.7 5.8 21.4 4.2 11.5 11.8 1.3 24.2 6.4 2.1 33.4 3.8 10.5 3.9 19.3 24.1 9.4 0.5 3.7 6.7 0.0 16.7 5.3 0.1 0.0 2.9 16.7 3.3 24.9 9.4 3.3 2.2 3.9 3.3 3.1 6.2 0.4 0.8 3.5 15.0 5.8 1.3 6.5 3.8 4.1 1.0 2.5 15.4 12.0 6.2 49.0 15.7 13.4 54.7 23.2 43.7 19.3 37.6 55.5 12.4 14.0 36.3 49.0 11.6 45.9 24.6 6.4 46.2 33.3 7.4 7.0 6.5 7.9 7.2 9.0 10.0 7.2 7.6 9.0 7.5 8.2 20.3 9.6 7.7 0.3 15.9 1.8 1.9 2.8 8.0 0.2 3.6 2.8 4.9 0.0 5.2 0.0 0.0 2.5 26.9 6.4 1.9 5.3 4.6 4.2 9.4 22.1 1.2 9.9 1.4 2.3 1.6 11.1 7.1 4.3 3.8 8.7 15.7 4.0 4.3 0.0 2.1 8.9 0.0 20.8 4.0 18.0 4.1 12.4 3.6 2.8 12.6 2.3 33.0 1.5 0.4 2.4 3.9 2.2 30.5 2.0 12.8 1.1 3.3 0.0 6.6 4.9 4.0 0.4 0.3 3.1 2.0 0.5 27.1 12.3 6.2 1.9 C10orf143 LINC00959 ENSG00000237489 "Chromosome 10 open reading frame 143" A0A1B0GUT2 10 130020025-130110830 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6.7;Breast glandular cells: 8.2;Breast myoepithelial cells: 9.7;Collecting duct cells: 11.0;Distal tubular cells: 13.7;Proximal tubular cells: 12.8;Theca cells: 7.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 9.6;MCF7: 8.8;NB-4: 13.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" "unprognostic (3.58e-2)" "unprognostic (3.36e-2)" "unprognostic (5.61e-2)" "unprognostic (1.24e-2)" "unprognostic (8.12e-2)" "unprognostic (6.64e-3)" "unprognostic (8.68e-3)" "unprognostic (2.48e-3)" "unprognostic (1.59e-1)" "unprognostic (8.61e-2)" "unprognostic (7.26e-4)" "unprognostic (1.34e-1)" "unprognostic (2.36e-7)" "unprognostic (2.06e-1)" "unprognostic (3.29e-1)" "unprognostic (1.90e-1)" "unprognostic (1.49e-2)" 3.5 4.1 3.5 3.3 3.6 2.3 4.9 3.6 4.7 4.7 3.7 6.9 5.2 5.5 5.8 3.5 4.7 3.8 2.4 3.1 3.4 5.7 4.7 2.9 5.2 3.8 3.6 3.9 4.3 3.9 4.5 1.0 3.7 5.7 3.3 1.6 3.8 6.6 9.6 4.3 4.5 3.9 3.7 5.4 4.2 3.9 3.6 5.5 5.8 5.0 4.7 6.0 4.3 3.5 1.1 1.5 1.7 3.5 9.6 3.6 0.2 2.1 3.0 0.9 1.3 0.0 0.9 7.3 0.4 2.0 1.1 1.5 0.6 0.1 0.3 2.0 1.1 1.3 0.1 0.9 3.8 3.5 1.4 3.5 1.9 0.4 2.2 1.1 0.5 5.9 0.2 1.6 3.3 8.8 1.5 13.5 3.5 1.6 1.4 1.3 0.2 0.3 3.2 0.6 0.8 1.0 1.3 0.4 0.9 1.3 0.2 1.1 0.4 1.3 0.2 3.7 0.3 2.1 4.3 1.1 2.5 0.6 0.0 0.0 6.5 4.0 16.7 10.6 17.8 20.7 18.1 19.3 11.4 17.6 17.9 23.6 1.2 22.0 9.7 7.3 23.6 9.1 3.5 3.6 3.6 4.7 3.1 3.4 3.8 3.6 3.7 3.7 3.6 3.5 3.1 0.0 6.7 0.0 2.1 0.0 0.0 0.0 0.0 0.0 8.2 9.7 0.0 0.0 2.5 11.0 0.0 0.7 5.0 0.0 13.7 4.2 0.0 3.9 3.2 1.1 0.0 0.0 0.0 3.1 0.1 1.4 0.0 2.2 1.3 3.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 12.8 5.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.3 3.1 7.8 0.0 0.0 C14orf180 "C14orf77, NRAC" ENSG00000184601 "Chromosome 14 open reading frame 180" Q8N912 14 104579764-104590515 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.8;breast: 26.7;heart muscle: 109.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.7;Cardiomyocytes: 7.6;Fibroblasts: 2.0;Hepatic stellate cells: 3.3;Horizontal cells: 3.3;Smooth muscle cells: 1.4" "Cancer enhanced" "Detected in single" "renal cancer: 0.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "ASC diff: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.48e-2)" "unprognostic (1.55e-1)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (1.60e-1)" "unprognostic (3.19e-3)" "unprognostic (1.89e-1)" "unprognostic (3.12e-2)" "unprognostic (3.89e-2)" "unprognostic (2.32e-1)" "unprognostic (9.80e-2)" 40.8 3.1 0.0 0.1 0.2 0.0 26.7 0.2 0.2 0.9 13.5 0.9 0.3 1.1 0.0 0.0 1.8 0.2 109.5 1.5 0.0 1.8 4.1 0.4 0.0 0.5 0.8 0.8 0.8 0.0 1.8 0.8 0.5 0.6 0.0 0.1 0.9 0.4 5.7 0.6 1.4 0.0 0.0 0.5 2.2 0.1 0.4 0.0 0.9 0.7 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 1.5 0.0 0.5 0.8 0.5 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.4 7.6 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 C1GALT1C1 "C1GALT2, COSMC" ENSG00000171155 "C1GALT1 specific chaperone 1" Q96EU7 X 120625674-120630054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010666, HPA015632" Approved Approved Vesicles NA NA 21000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 51: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA010666: , HPA015632: AB_1845625" "prognostic unfavorable (5.66e-4)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.98e-1)" "unprognostic (3.07e-2)" "unprognostic (5.26e-3)" "unprognostic (4.34e-2)" "unprognostic (2.50e-1)" "unprognostic (2.18e-2)" "unprognostic (8.10e-2)" "unprognostic (3.85e-2)" "unprognostic (3.07e-1)" "unprognostic (3.98e-2)" "unprognostic (4.48e-2)" "unprognostic (1.55e-1)" "unprognostic (6.05e-3)" "unprognostic (3.78e-2)" 15.3 27.8 4.2 8.7 4.6 2.8 14.5 4.9 5.6 15.7 6.4 15.7 10.1 12.2 16.8 14.8 13.7 8.3 17.7 4.2 5.9 13.8 21.0 12.0 8.8 4.9 5.2 9.7 15.8 16.3 33.9 9.2 4.9 10.5 14.5 6.3 20.0 11.1 7.8 5.8 13.2 9.5 4.8 13.0 13.5 6.1 4.5 7.4 13.2 7.0 9.6 11.5 12.8 5.2 15.9 15.1 8.2 14.2 126.7 24.0 13.0 28.4 39.9 14.7 27.7 9.9 49.8 10.3 13.9 57.6 28.4 21.9 16.2 13.9 23.4 17.6 19.6 6.6 13.1 14.7 19.7 11.7 10.1 21.0 12.1 18.3 6.1 36.9 47.0 5.1 4.2 11.8 17.5 21.6 3.9 11.0 9.3 53.3 15.1 1.8 6.4 28.5 29.9 10.6 9.0 8.6 27.0 18.4 14.6 15.0 15.9 11.2 43.4 6.7 8.3 27.2 26.9 5.1 7.9 8.2 24.6 22.7 15.0 12.1 12.3 20.4 12.0 16.4 13.3 12.3 15.4 13.0 14.6 7.6 15.6 12.5 22.7 12.3 13.6 16.7 15.8 12.2 4.2 4.6 4.9 5.6 4.2 5.9 4.9 5.2 4.9 4.8 4.5 5.2 27.1 6.4 10.4 6.5 16.3 6.8 22.7 107.9 15.4 8.3 17.6 10.0 17.6 14.3 75.9 38.6 2.1 56.9 16.3 18.7 15.6 40.3 2.7 30.5 20.2 27.6 13.8 5.9 4.7 44.3 51.7 34.7 10.7 25.3 2.5 14.5 21.4 22.3 24.1 20.2 6.5 20.8 77.3 16.2 11.4 6.4 22.7 19.6 30.2 3.7 20.7 17.5 15.5 5.5 10.1 30.0 20.8 19.2 50.1 10.7 16.9 20.3 71.0 10.5 6.6 18.1 24.4 6.5 8.4 14.1 7.2 20.0 15.2 25.8 21.5 20.5 C1orf198 "DKFZp667D152, FLJ14525, FLJ16283, FLJ38847, MGC10710" ENSG00000119280 "Chromosome 1 open reading frame 198" Q9H425 1 230837119-230869589 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 131.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 13.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 13.1" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 138.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004798 Approved Supported Cytosol "Intracellular and membrane" NA NA 80000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA004798: AB_1848722" "unprognostic (7.44e-2)" "unprognostic (1.89e-1)" "unprognostic (1.17e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-2)" "unprognostic (2.46e-1)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (2.32e-1)" "unprognostic (3.75e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.50e-5)" "unprognostic (3.53e-2)" "unprognostic (4.95e-2)" "unprognostic (1.38e-1)" "unprognostic (3.77e-2)" 39.7 13.4 77.5 11.0 106.4 5.3 30.0 93.3 83.7 36.5 41.1 35.2 11.8 38.8 14.9 14.9 32.7 32.3 45.4 72.6 85.0 17.3 14.7 66.9 15.5 108.4 105.1 27.3 27.9 20.1 7.6 31.1 108.9 21.4 11.4 9.8 23.4 32.3 106.2 34.0 13.9 46.1 97.8 18.0 29.9 6.8 94.5 6.6 34.9 26.1 9.1 33.2 26.4 131.3 22.4 16.7 44.9 30.8 81.9 59.9 76.7 40.4 63.7 20.4 20.6 53.0 12.3 26.8 24.5 138.1 10.3 14.1 23.5 8.9 15.0 87.5 22.3 4.2 15.0 17.9 35.7 13.9 4.0 72.9 13.4 8.1 8.9 43.7 12.9 16.9 8.7 9.0 14.1 15.0 11.0 6.6 52.6 49.5 13.7 25.6 32.1 6.0 16.2 26.7 26.0 41.5 20.5 27.2 14.2 23.6 34.6 11.8 10.3 32.9 32.8 7.7 24.5 16.0 7.7 8.0 8.7 8.7 95.3 13.1 1.3 0.3 2.0 2.7 2.4 1.9 1.3 0.8 1.7 1.2 2.6 2.3 1.0 2.9 1.3 0.2 0.6 4.7 77.5 106.4 93.3 83.7 72.6 85.0 108.4 105.1 108.9 97.8 94.5 131.3 11.1 192.3 23.2 35.3 1.2 26.0 13.1 6.4 7.4 2.0 32.7 23.7 36.4 32.9 17.3 11.0 10.4 17.5 1.3 2.6 1.9 41.9 11.4 8.2 8.9 11.6 5.4 9.9 2.6 26.3 32.2 33.2 3.6 10.6 2.5 15.1 8.6 4.5 11.0 25.2 5.3 9.0 8.2 1.8 19.4 8.3 13.4 11.6 65.8 13.1 3.6 12.8 0.0 6.0 67.5 31.1 3.7 9.1 2.5 21.3 2.8 7.4 12.2 4.6 32.9 26.8 45.1 10.4 5.7 8.9 29.0 12.9 3.4 5.2 6.9 18.7 C1orf54 FLJ23221 ENSG00000118292 "Chromosome 1 open reading frame 54" Q8WWF1 1 150268200-150280916 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Endothelial cells: 101.3;Kupffer cells: 145.7;Langerhans cells: 282.7;Leydig cells: 95.1;Peritubular cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "myeloid DC: 103.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 103.5" "Cell line enhanced" "Detected in many" "AF22: 77.8;AN3-CA: 110.5;ASC diff: 86.1;ASC TERT1: 141.3;HSkMC: 102.1;HUVEC TERT2: 108.4;U-87 MG: 68.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA026518, HPA043874" Approved Approved "Plasma membrane" "Secreted to blood" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA026518: AB_1845647, HPA043874: AB_2732511" "unprognostic (4.64e-3)" "unprognostic (6.81e-3)" "unprognostic (4.01e-3)" "unprognostic (5.69e-3)" "unprognostic (2.22e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-2)" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.16e-2)" "unprognostic (8.06e-2)" "unprognostic (1.33e-2)" "unprognostic (4.48e-2)" 37.6 19.1 59.8 26.4 60.7 11.9 30.7 62.0 96.2 27.6 56.2 25.9 13.3 30.1 39.1 17.9 33.2 46.4 34.6 57.6 62.2 28.4 29.7 29.2 62.6 61.9 61.8 7.9 5.1 14.5 10.5 59.2 62.0 28.7 25.9 16.2 8.4 75.6 24.6 11.1 15.0 60.3 63.5 69.4 12.7 13.9 64.2 30.8 13.9 48.3 27.9 36.2 18.2 62.4 1.6 0.3 77.8 110.5 86.1 141.3 2.2 14.0 20.5 3.8 12.0 0.9 1.9 0.6 4.1 12.3 1.5 2.7 0.2 0.5 5.6 1.4 12.2 1.9 2.0 1.3 17.7 3.9 2.6 102.1 5.9 24.8 1.9 13.2 108.4 1.8 1.8 12.2 15.0 4.2 0.7 24.0 5.7 0.1 3.9 18.8 1.7 1.4 1.1 6.1 1.5 1.3 1.4 0.8 7.5 16.4 1.4 58.0 0.7 28.1 2.1 0.8 0.9 5.0 4.8 1.2 68.3 3.1 0.7 0.1 21.2 0.8 0.6 20.8 2.5 0.9 3.8 1.7 103.5 0.7 3.5 2.0 1.0 0.8 5.6 2.1 1.9 6.4 59.8 60.7 62.0 96.2 57.6 62.2 61.9 61.8 62.0 63.5 64.2 62.4 115.7 3.2 4.5 19.6 3.3 6.4 2.2 2.4 1.8 0.8 2.3 3.7 10.6 2.8 2.5 22.0 0.0 1.3 1.5 2.0 76.3 0.7 9.4 3.1 37.6 101.3 1.2 0.4 4.1 2.3 0.8 29.3 5.1 3.1 1.3 0.7 51.8 1.3 45.3 0.0 3.8 1.3 0.0 145.7 282.7 19.6 95.1 65.6 12.4 16.9 24.9 23.4 1.0 0.5 0.3 2.0 1.5 104.2 3.0 4.9 2.7 4.9 0.5 1.6 32.9 7.5 70.4 16.6 1.9 7.5 5.1 3.6 3.3 5.2 1.4 8.4 C1QTNF1 "CTRP1, FLJ90694, GIP, ZSIG37" ENSG00000173918 "C1q and TNF related 1" Q9BXJ1 17 79022814-79049788 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 214.2;heart muscle: 319.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 120.0;Sertoli cells: 105.2;Smooth muscle cells: 105.8;Syncytiotrophoblasts: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 313.5;BJ hTERT+: 72.9;HHSteC: 112.3;HSkMC: 61.3;U-87 MG: 66.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025429, HPA051101" Uncertain Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 314000000 40000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "CAB025429: , HPA051101: AB_2681343" "unprognostic (2.58e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (1.20e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" "unprognostic (7.11e-2)" "unprognostic (3.18e-1)" "unprognostic (1.07e-2)" "unprognostic (1.23e-2)" "unprognostic (7.48e-2)" "unprognostic (9.81e-3)" "unprognostic (5.83e-2)" "prognostic unfavorable (9.09e-9)" "unprognostic (1.93e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-2)" "unprognostic (1.95e-2)" 214.2 75.3 9.5 14.8 15.2 0.5 156.0 16.1 13.3 50.2 45.3 38.3 4.6 45.1 6.5 18.9 63.5 24.3 319.1 9.1 18.2 25.3 45.7 44.4 14.0 18.3 25.4 70.5 14.9 13.5 17.5 42.2 18.0 57.1 6.3 0.9 34.9 44.0 27.0 38.6 29.3 13.3 14.1 35.7 25.0 5.4 21.9 5.1 115.0 21.3 6.6 34.7 42.3 13.2 0.1 32.3 0.3 0.1 313.5 27.1 0.2 13.6 72.9 7.0 11.9 2.7 14.0 0.1 1.5 5.1 18.1 0.7 1.0 0.5 5.0 0.1 3.5 0.2 11.7 1.5 112.3 0.1 0.2 61.3 0.2 14.5 0.8 9.3 8.8 1.6 0.1 0.3 1.6 0.1 0.3 0.2 3.0 3.7 27.9 0.1 22.3 0.4 0.0 0.4 1.3 5.3 9.2 1.8 32.7 1.2 0.0 0.0 1.4 32.6 0.8 4.0 4.8 0.3 0.1 0.1 66.2 0.2 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.5 15.2 16.1 13.3 9.1 18.2 18.3 25.4 18.0 14.1 21.9 13.2 36.1 0.0 0.6 4.9 0.4 6.5 0.7 12.3 0.6 0.1 9.2 1.8 10.8 5.7 0.5 1.8 0.0 21.5 0.4 3.2 0.0 19.5 0.1 0.6 17.9 38.3 4.8 2.7 0.2 5.9 1.5 23.6 2.6 0.6 0.0 25.3 120.0 1.9 2.6 0.0 0.9 6.3 2.0 7.5 11.3 0.7 10.5 1.1 3.6 5.6 10.9 0.5 0.0 0.5 0.3 3.7 3.1 3.4 0.1 1.8 0.9 0.2 0.3 0.5 105.2 12.7 105.8 0.0 0.7 0.4 4.5 47.3 0.8 18.1 5.2 0.6 C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.8;Fibroblasts: 32.3;Leydig cells: 22.7;Peritubular cells: 31.6;Skeletal myocytes: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 4.2;ASC TERT1: 2.8;HSkMC: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" NA NA 238000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" 7.8 1.4 1.2 1.6 1.2 0.0 4.7 1.2 2.6 23.1 0.0 8.6 1.2 16.5 10.2 6.0 6.3 14.0 7.0 0.8 1.8 5.5 1.2 10.8 1.2 1.1 1.8 20.9 0.8 0.1 1.1 7.2 0.9 9.5 4.2 0.1 2.5 3.2 0.6 3.2 3.8 12.0 0.6 9.7 9.0 1.7 1.8 0.4 3.8 6.6 0.5 10.3 10.3 1.3 0.0 0.0 0.0 0.0 4.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.6 0.8 1.8 1.1 1.8 0.9 0.6 1.8 1.3 1.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 15.8 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.1 0.2 6.5 0.5 0.0 0.0 1.0 0.0 0.3 32.3 0.0 0.6 0.0 2.0 0.0 0.0 0.1 1.7 4.4 0.0 0.0 0.0 3.2 0.5 22.7 0.3 5.4 6.5 0.0 0.3 0.0 2.5 0.7 0.0 0.0 31.6 0.2 0.1 0.0 2.8 0.0 1.2 6.6 15.2 9.9 0.0 0.1 0.6 3.0 0.0 0.7 5.7 0.0 0.1 C1R ENSG00000159403 "Complement C1r" 12 7080214-7092540 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "liver: 1425.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 442.3;Fibroblasts: 684.4;Hepatocytes: 1444.2;Leydig cells: 1142.6;Peritubular cells: 388.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1089.8;ASC TERT1: 546.0;BJ hTERT+: 461.9;BJ hTERT+ SV40 Large T+ RasG12V: 303.4;HSkMC: 672.1" "Low region specificity" "Detected in many" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001251: AB_2666252, HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" 540.6 203.6 15.8 122.4 15.9 1.1 400.6 15.9 23.3 470.5 21.7 277.3 38.3 353.8 80.8 119.0 526.3 279.1 458.7 15.4 19.6 148.9 1425.6 340.3 72.4 23.4 19.9 644.3 88.0 11.0 63.9 52.4 18.4 205.2 100.9 5.8 158.3 87.0 69.4 177.7 228.1 157.7 18.1 192.1 242.7 46.7 18.1 34.7 223.4 74.2 75.3 468.4 394.3 18.0 1.2 8.9 0.9 9.1 1089.8 546.0 0.4 108.9 461.9 143.0 303.4 1.4 2.4 0.5 4.5 108.8 11.8 2.3 11.8 5.5 18.3 18.3 1.1 0.5 4.1 3.6 226.5 0.8 2.3 672.1 3.2 74.7 4.7 121.0 2.9 0.5 0.3 20.5 21.2 0.1 8.0 0.8 3.1 0.1 0.9 8.6 3.8 0.8 0.9 5.5 0.4 2.3 95.1 3.7 2.8 1.3 0.2 0.2 0.4 38.3 6.3 152.1 0.8 1.1 3.0 0.2 53.1 1.0 5.4 0.0 0.0 0.6 0.3 0.0 0.5 0.0 0.2 0.7 0.0 0.0 0.6 0.6 0.5 0.8 0.0 0.0 0.3 0.1 15.8 15.9 15.9 23.3 15.4 19.6 23.4 19.9 18.4 18.1 18.1 18.0 45.4 22.4 90.5 3.6 7.1 54.7 58.8 76.6 33.6 0.3 5.9 30.9 20.8 183.0 22.9 18.4 2.1 4.1 1.8 0.7 3.9 280.8 4.6 13.3 442.3 45.4 0.0 40.6 0.9 44.5 3.7 684.4 16.3 11.6 10.1 24.9 114.9 1444.2 11.2 0.0 0.3 0.7 0.0 40.9 66.9 29.2 1142.6 7.0 53.4 13.1 1.6 16.0 0.0 2.5 0.1 51.1 1.3 388.1 6.2 17.7 0.3 6.1 5.3 1.4 170.9 87.5 140.4 6.8 6.7 5.6 40.1 5.2 11.5 15.2 0.7 11.2 C1RL "C1r-LP, C1RL1" ENSG00000139178 "Complement C1r subcomponent like" Q9NZP8 12 7089587-7109238 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 141.9" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 54.2;Hepatocytes: 140.0;Leydig cells: 55.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 38.2;HSkMC: 43.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011338, CAB026172" Supported "Secreted to blood" NA NA 5500000000 15000000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "CAB026172: , HPA011338: AB_1847111" "prognostic favorable (7.92e-4)" "unprognostic (7.76e-2)" "unprognostic (3.91e-3)" "unprognostic (5.25e-3)" "unprognostic (2.92e-3)" "unprognostic (9.60e-2)" "unprognostic (2.75e-3)" "unprognostic (7.76e-2)" "unprognostic (1.22e-1)" "unprognostic (4.34e-1)" "unprognostic (9.58e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.75e-1)" "unprognostic (5.74e-2)" "unprognostic (2.52e-1)" "unprognostic (2.26e-3)" 38.3 72.5 3.4 12.2 3.3 8.2 36.5 2.6 3.1 38.6 7.1 28.8 7.6 30.2 6.3 17.5 40.8 11.7 18.4 2.7 4.0 20.1 141.9 33.1 9.5 7.4 5.0 49.4 36.7 8.0 17.5 5.1 4.4 29.3 8.7 1.5 33.7 6.9 11.0 18.1 26.3 13.7 3.7 32.3 27.5 6.1 3.9 6.9 21.7 6.0 7.7 38.1 27.5 3.3 3.0 7.7 0.7 7.9 22.4 38.2 5.4 4.9 22.7 5.0 14.8 4.9 13.4 1.3 4.1 4.1 5.0 6.4 2.1 8.1 1.9 12.0 0.4 4.8 8.5 11.4 18.7 1.0 21.9 43.1 15.7 3.0 9.3 23.3 5.3 2.8 3.6 3.1 3.1 0.1 0.7 0.9 1.4 0.6 0.2 2.7 0.0 1.0 13.1 13.2 0.6 1.7 16.7 2.0 2.8 1.3 1.9 4.1 5.0 4.3 7.7 4.9 0.9 2.3 1.0 0.2 8.1 3.4 2.0 3.8 0.7 4.0 0.6 1.1 0.3 1.2 0.6 0.5 0.8 0.5 0.4 0.4 5.4 0.3 1.3 0.4 0.4 0.4 3.4 3.3 2.6 3.1 2.7 4.0 7.4 5.0 4.4 3.7 3.9 3.3 11.0 16.0 38.6 7.5 8.4 3.8 15.4 16.4 25.6 0.5 15.6 14.5 2.6 30.0 24.6 5.5 2.1 0.2 7.3 8.3 1.9 36.3 0.1 7.9 22.6 14.6 4.2 7.8 10.2 54.2 0.4 29.0 27.5 10.4 3.8 13.8 25.0 140.0 3.6 0.0 1.3 7.7 10.2 10.0 4.9 3.0 55.6 10.2 3.6 14.0 13.3 4.0 21.6 2.0 0.4 25.8 9.7 20.3 8.0 10.2 9.3 8.2 15.9 1.1 0.0 11.8 10.1 0.6 0.9 8.5 3.1 0.1 9.7 13.6 9.5 8.7 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 2915.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 687.0;Hepatocytes: 2795.1;Leydig cells: 1193.2;Peritubular cells: 640.1" "Cancer enhanced" "Detected in all" "liver cancer: 276.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.2" "Cell line enhanced" "Detected in many" "ASC diff: 769.5;ASC TERT1: 1012.7;BJ hTERT+: 336.1;HSkMC: 540.2" "Not detected" "Not detected" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 93000000000 14000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favorable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 416.4 136.1 26.4 207.7 28.5 1.7 252.5 27.1 43.1 309.2 36.7 192.4 84.6 209.0 147.2 152.9 315.4 543.8 191.5 25.4 34.8 60.2 2915.2 224.9 209.2 44.3 31.7 485.9 62.1 21.8 33.1 52.9 31.2 174.4 215.2 9.7 96.9 139.1 57.0 104.1 154.2 251.8 30.9 168.5 150.1 90.0 30.9 88.1 139.0 154.7 192.5 455.7 189.8 31.3 0.2 18.6 1.2 10.2 769.5 1012.7 4.5 143.3 336.1 74.7 135.7 0.9 2.0 0.5 19.7 179.6 20.2 1.1 0.3 2.1 6.7 0.7 0.7 0.5 5.6 48.2 230.3 1.8 0.9 540.2 2.8 60.2 4.4 94.2 0.1 0.2 0.4 0.1 9.9 0.0 0.4 1.6 10.3 0.0 0.6 0.2 1.1 1.5 3.1 2.5 0.8 0.9 86.6 1.8 2.1 17.4 0.1 0.0 0.5 34.2 2.6 133.8 0.2 0.6 0.5 0.8 73.6 1.2 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 26.4 28.5 27.1 43.1 25.4 34.8 44.3 31.7 31.2 30.9 30.9 31.3 37.6 16.0 41.0 9.4 5.7 76.2 18.9 22.2 23.9 0.9 4.5 15.4 21.5 171.6 15.5 3.7 0.0 3.7 0.7 0.1 1.9 285.2 6.6 8.7 272.4 30.6 0.0 112.2 2.9 42.9 2.5 687.0 11.2 7.3 5.1 25.7 93.5 2795.1 8.1 5.0 1.7 0.0 2.0 62.8 103.7 29.9 1193.2 6.4 88.9 19.7 1.0 15.2 0.0 1.5 0.6 31.7 0.1 640.1 1.8 9.7 0.0 7.1 4.6 1.1 138.1 34.9 127.6 6.3 5.3 6.3 53.8 2.6 12.8 30.7 0.2 5.2 C20orf194 DKFZp434N061 ENSG00000088854 "Chromosome 20 open reading frame 194" Q5TEA3 20 3249306-3407669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 226.9;Cone photoreceptor cells: 202.3;Excitatory neurons: 205.6;Inhibitory neurons: 163.1;Oligodendrocyte precursor cells: 135.7;Oligodendrocytes: 191.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052103, HPA067418" Approved Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 41: Basophils - Cellular respiration" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center, Cytosol" "HPA052103: AB_2681727, HPA067418: AB_2685835" "unprognostic (9.77e-2)" "unprognostic (8.39e-2)" "unprognostic (5.03e-3)" "unprognostic (1.83e-1)" "unprognostic (1.18e-1)" "unprognostic (4.26e-2)" "unprognostic (1.66e-2)" "unprognostic (7.64e-2)" "unprognostic (6.41e-2)" "unprognostic (1.68e-1)" "prognostic favorable (1.68e-4)" "unprognostic (2.97e-1)" "prognostic favorable (7.68e-4)" "unprognostic (9.58e-3)" "unprognostic (3.70e-1)" "unprognostic (2.00e-1)" "unprognostic (7.52e-2)" 11.8 9.5 19.7 5.2 22.4 3.6 8.7 18.5 20.1 10.1 6.8 14.4 4.1 10.4 5.4 8.4 9.8 8.3 15.3 19.5 21.4 11.2 2.6 10.0 4.5 21.5 22.9 12.3 6.3 4.2 8.8 9.1 21.1 8.6 4.3 16.4 5.8 11.6 32.3 5.6 6.6 12.9 19.6 7.3 9.7 10.4 21.8 3.8 9.6 11.6 2.9 12.6 8.9 26.0 4.0 3.6 9.7 4.7 19.7 21.6 1.1 9.2 10.3 6.0 7.5 0.0 4.3 0.0 2.5 12.3 7.7 4.7 3.7 9.1 8.2 0.9 1.8 1.1 1.4 10.0 9.2 1.2 0.5 17.7 6.9 7.9 6.8 8.6 12.2 3.5 2.0 0.0 8.9 1.8 2.5 6.5 2.9 2.2 2.3 2.9 8.8 0.1 7.8 8.1 1.9 5.7 4.1 7.2 12.0 8.3 6.8 11.3 13.7 7.5 3.2 4.7 4.5 0.1 0.0 0.0 2.4 1.2 5.8 0.4 0.8 0.0 0.5 0.4 0.2 0.2 0.3 0.4 0.9 0.4 0.1 0.3 0.0 0.0 0.4 1.0 0.4 0.2 19.7 22.4 18.5 20.1 19.5 21.4 21.5 22.9 21.1 19.6 21.8 26.0 23.6 28.9 9.2 226.9 3.7 6.9 6.7 10.8 8.6 35.1 10.1 10.8 28.5 15.7 10.3 12.9 202.3 1.8 8.9 0.1 1.9 9.1 31.8 10.6 15.9 20.1 0.0 4.0 205.6 4.7 5.4 13.4 19.4 12.1 14.0 53.3 25.7 2.3 19.6 30.3 163.1 0.5 4.1 34.0 25.5 8.9 19.9 22.4 8.8 89.9 14.1 10.0 3.1 135.7 191.2 9.4 14.8 13.5 1.5 5.4 7.4 8.4 21.8 13.9 13.1 18.4 22.2 28.5 25.0 7.2 5.7 1.8 7.8 16.4 1.4 5.2 C2CD2 "C21orf25, C21orf258, DKFZP586F0422, TMEM24L" ENSG00000157617 "C2 calcium dependent domain containing 2" Q9Y426 21 41885112-41954018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 126.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 51.6;Cone photoreceptor cells: 83.4;Granulosa cells: 100.0;Theca cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 79.1;SK-BR-3: 44.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030922, HPA030924" Enhanced Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA030922: AB_2673660, HPA030924: AB_10669873" "unprognostic (3.02e-3)" "unprognostic (3.69e-2)" "unprognostic (2.21e-2)" "unprognostic (9.63e-2)" "unprognostic (3.15e-3)" "unprognostic (2.93e-2)" "unprognostic (2.39e-2)" "unprognostic (3.44e-2)" "unprognostic (3.00e-2)" "unprognostic (4.39e-2)" "unprognostic (2.43e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.68e-5)" "unprognostic (1.99e-1)" "unprognostic (4.56e-2)" "unprognostic (1.06e-2)" "unprognostic (1.48e-1)" 39.9 126.3 18.6 8.3 18.0 1.3 23.3 18.4 19.8 12.0 16.9 12.9 4.9 8.3 8.4 10.7 9.4 8.3 7.5 16.4 18.6 10.1 8.6 7.9 9.7 21.8 20.9 18.9 11.3 29.2 7.2 5.2 20.2 17.3 5.8 24.6 10.8 11.5 2.8 15.6 9.0 7.8 20.5 41.4 11.7 3.3 23.4 6.7 8.5 4.1 7.9 12.8 11.4 26.1 13.4 5.5 3.9 8.9 79.1 21.7 15.1 9.3 14.4 5.7 5.2 8.7 15.0 0.2 5.0 18.0 14.0 1.5 13.9 9.7 7.2 0.9 6.2 2.3 7.1 7.1 10.6 1.0 0.0 14.0 8.9 30.3 11.7 12.5 27.1 0.7 8.4 0.1 15.3 1.2 1.9 2.7 21.4 5.7 18.7 1.4 5.7 8.0 8.5 27.8 6.3 2.8 10.1 44.6 8.1 7.6 11.7 5.9 9.3 13.5 1.9 4.5 7.6 5.0 7.9 1.1 39.2 7.7 2.8 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.2 0.1 0.3 0.1 0.5 0.3 0.1 0.3 0.1 0.0 0.3 0.1 18.6 18.0 18.4 19.8 16.4 18.6 21.8 20.9 20.2 20.5 23.4 26.1 24.8 3.2 15.5 20.5 4.4 4.1 9.1 7.6 15.9 51.6 8.2 7.0 3.1 8.6 8.3 3.7 83.4 12.8 4.4 3.4 0.0 5.6 0.3 6.0 6.7 19.3 4.9 5.9 20.3 8.5 4.8 11.9 17.9 8.3 0.0 100.0 46.1 5.2 3.6 1.7 14.4 6.9 6.1 7.0 10.5 0.2 3.7 5.6 1.8 24.4 2.5 3.6 3.1 11.6 18.8 8.1 5.0 2.2 8.1 15.9 3.0 2.5 7.7 36.9 13.1 7.4 17.9 0.1 3.0 14.3 2.6 9.3 2.8 82.4 6.9 16.6 C4orf3 "ALN, HCVFTP1" ENSG00000164096 "Chromosome 4 open reading frame 3" Q8WVX3 4 119296419-119304445 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 1070.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026907 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "HPA026907: AB_10600760" "unprognostic (2.97e-1)" "unprognostic (4.68e-2)" "unprognostic (3.32e-1)" "unprognostic (6.85e-3)" "unprognostic (9.30e-2)" "unprognostic (7.15e-3)" "unprognostic (2.04e-1)" "unprognostic (8.85e-2)" "unprognostic (4.90e-2)" "unprognostic (7.11e-2)" "unprognostic (9.94e-3)" "unprognostic (1.84e-1)" "prognostic favorable (3.46e-4)" "unprognostic (8.32e-2)" "unprognostic (2.65e-1)" "unprognostic (3.90e-1)" "unprognostic (1.59e-1)" 80.0 67.8 96.4 54.1 107.1 34.1 69.4 103.1 148.1 123.2 83.3 80.2 60.5 79.7 77.9 268.2 68.9 65.1 107.8 90.1 99.6 97.9 110.8 70.3 61.3 107.9 104.9 85.5 51.5 55.5 56.6 60.3 106.4 71.8 43.6 74.7 89.6 69.8 79.6 89.3 67.3 70.6 109.6 63.1 49.6 39.8 109.2 64.8 71.4 59.7 56.8 75.9 150.2 112.8 116.8 13.7 58.4 49.8 107.1 97.0 34.1 59.3 31.6 35.3 62.6 15.6 44.5 95.9 36.6 87.3 31.0 24.8 29.6 54.1 61.8 57.1 21.3 40.9 33.5 67.9 35.9 64.7 42.8 96.4 64.5 30.0 14.4 120.6 52.8 29.1 33.8 50.4 137.6 41.8 50.9 64.0 24.2 60.7 20.9 32.9 62.6 27.3 53.5 32.2 38.4 54.8 46.4 58.5 43.2 56.9 32.6 37.5 55.7 80.3 34.6 52.5 21.4 51.3 59.8 37.2 156.7 36.7 40.9 257.8 110.0 145.4 85.1 132.6 92.9 126.7 109.6 101.5 95.1 104.8 120.4 114.4 239.4 109.6 128.0 131.6 112.9 157.1 96.4 107.1 103.1 148.1 90.1 99.6 107.9 104.9 106.4 109.6 109.2 112.8 213.2 157.0 150.5 11.4 211.3 315.5 292.0 809.1 132.1 79.1 198.4 191.9 544.4 158.7 456.3 222.5 25.0 321.5 228.9 117.0 383.5 288.5 38.1 272.5 148.7 245.6 68.4 78.6 22.2 179.1 403.9 215.0 46.4 134.3 186.1 108.0 234.9 446.4 317.4 153.1 21.6 170.2 408.9 303.5 298.4 31.0 167.4 244.9 199.3 16.9 423.9 233.4 253.3 6.6 16.3 207.6 196.8 215.5 239.0 392.5 500.1 1070.2 542.7 78.9 197.2 145.8 246.0 182.7 67.0 245.9 346.6 445.7 203.2 150.3 135.8 428.1 C6 ENSG00000039537 "Complement C6" P13671 5 41142116-41261438 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "liver: 665.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 127.2;Hepatocytes: 376.9;Late spermatids: 54.8;Leydig cells: 120.2;Respiratory ciliated cells: 58.0" "Group enriched" "Detected in many" 7 "liver cancer: 49.0;pancreatic cancer: 12.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 4.5;ASC TERT1: 6.2;HSkMC: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043823, CAB069427" Enhanced "Secreted to blood" NA NA 45000000000 9200000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB069427: AB_1614336, HPA043823: AB_10960262" "unprognostic (9.79e-2)" "unprognostic (1.96e-2)" "unprognostic (5.94e-3)" "unprognostic (3.02e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (1.12e-3)" "unprognostic (4.66e-2)" "unprognostic (3.72e-2)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (3.04e-3)" "prognostic favorable (4.31e-4)" "unprognostic (2.69e-4)" "unprognostic (1.61e-1)" "unprognostic (1.40e-2)" "unprognostic (3.51e-2)" 12.8 1.1 0.2 0.0 0.2 0.0 5.4 0.2 0.1 0.8 1.6 0.8 0.9 0.4 0.9 0.3 43.9 12.0 57.1 0.2 0.6 4.4 665.9 3.2 0.4 0.0 1.7 6.2 42.7 0.1 0.7 2.8 0.2 0.9 0.6 0.0 0.9 0.6 0.6 0.6 1.4 0.9 0.1 0.3 2.2 4.2 0.8 0.6 2.0 0.7 0.5 0.9 0.6 0.6 0.0 0.0 0.0 0.0 4.5 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.2 0.6 0.0 1.7 0.2 0.1 0.8 0.6 0.8 0.0 0.0 0.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 20.9 127.2 7.5 0.0 0.0 0.0 0.1 0.3 0.0 9.3 11.3 37.5 0.8 0.9 0.0 8.0 1.4 0.4 0.0 6.7 0.0 0.7 0.0 0.1 5.0 376.9 0.0 0.0 2.7 1.0 0.0 9.7 0.3 54.8 120.2 0.2 0.0 0.0 0.0 0.0 0.0 1.0 1.3 0.5 1.3 0.4 0.0 0.0 11.6 0.8 58.0 0.0 0.0 0.2 0.4 0.4 0.1 0.0 0.0 0.0 0.4 0.5 0.6 0.0 C6orf120 bA160E12.4 ENSG00000185127 "Chromosome 6 open reading frame 120" Q7Z4R8 6 169702190-169704856 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 116.9;Late spermatids: 272.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039626 Uncertain "Secreted to blood" NA NA 620000 "Cluster 26: Non-specific - Mitochondria" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "HPA039626: AB_10673361" "unprognostic (2.98e-2)" "prognostic unfavorable (2.26e-4)" "unprognostic (3.43e-2)" "unprognostic (1.03e-2)" "unprognostic (1.13e-1)" "unprognostic (4.30e-3)" "prognostic unfavorable (9.52e-5)" "unprognostic (1.78e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.56e-1)" "unprognostic (1.30e-1)" "unprognostic (1.63e-1)" "unprognostic (6.21e-3)" "unprognostic (2.88e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-3)" 21.6 16.6 10.2 14.5 10.7 7.7 15.2 10.8 11.5 13.1 9.8 15.5 16.3 11.2 9.3 13.4 10.3 13.1 9.6 10.6 10.6 19.3 28.0 10.6 16.4 8.8 10.8 15.6 14.2 12.0 6.1 20.0 9.5 12.0 14.4 26.3 13.7 12.0 13.8 9.0 15.9 13.4 10.7 13.7 14.8 8.7 11.2 12.4 10.4 13.2 15.5 15.2 6.7 12.2 13.9 10.9 26.2 40.1 71.4 59.3 29.6 28.5 40.9 23.3 27.2 14.9 12.7 11.8 22.4 35.0 38.7 20.8 17.2 26.1 38.9 20.0 41.6 16.8 10.5 31.4 50.6 28.2 25.7 73.2 21.0 27.8 32.0 40.8 28.6 26.7 45.0 32.8 40.6 25.1 15.3 19.3 22.4 24.3 12.7 11.1 14.4 32.0 28.9 15.3 10.6 24.0 23.7 14.9 19.6 29.7 24.9 36.7 31.8 9.8 19.2 52.3 19.6 42.2 69.3 16.7 32.5 25.7 26.3 6.2 7.9 7.1 3.2 7.6 4.3 3.2 4.7 5.6 6.3 4.9 6.2 5.2 4.2 3.1 6.0 2.1 3.4 3.9 10.2 10.7 10.8 11.5 10.6 10.6 8.8 10.8 9.5 10.7 11.2 12.2 11.3 16.0 5.3 7.2 14.1 9.8 12.6 9.9 12.0 15.3 12.5 9.4 8.8 5.7 10.3 14.7 25.0 27.5 13.2 20.2 9.8 10.6 116.9 9.7 18.5 9.7 14.3 18.3 9.5 15.8 31.6 19.5 16.3 10.8 9.5 11.3 8.9 18.9 16.6 8.4 12.9 12.7 14.2 16.9 6.5 272.5 17.7 13.6 19.6 1.9 15.2 28.6 10.3 11.1 10.3 10.9 10.3 11.7 18.8 13.1 22.4 12.7 12.4 24.6 0.0 10.3 10.8 15.4 12.3 12.6 10.2 29.0 10.9 9.2 12.9 14.7 C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 578.4;Hepatic stellate cells: 662.5;Leydig cells: 1058.5;Sertoli cells: 309.0;Theca cells: 503.1" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 116.5;HHSteC: 155.1;HSkMC: 212.1;SH-SY5Y: 146.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" 470.9 607.7 2.6 21.7 3.5 0.2 46.4 2.6 9.6 118.5 13.6 165.3 19.3 124.6 163.6 52.9 377.3 211.7 558.7 2.8 2.5 298.1 110.6 206.7 99.2 4.4 2.7 735.4 149.8 15.0 23.1 359.2 3.0 101.6 32.5 1.5 18.0 105.7 4.3 12.6 139.8 256.3 4.3 138.2 120.2 28.0 3.0 32.2 105.1 1.6 22.5 122.1 118.3 3.0 0.0 0.0 0.0 0.0 116.5 16.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 155.1 0.0 0.0 212.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 146.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.5 2.6 9.6 2.8 2.5 4.4 2.7 3.0 4.3 3.0 3.0 7.9 6.4 4.1 0.0 1.4 0.6 0.5 0.0 1.8 2.1 1.2 0.3 56.7 7.2 2.5 0.0 0.0 0.2 0.1 0.4 0.0 0.2 4.7 0.5 7.9 127.6 54.8 26.7 0.1 1.3 0.1 578.4 0.0 0.2 1.3 2.7 662.5 8.3 0.5 43.7 0.3 1.3 0.0 14.5 4.2 29.8 1058.5 1.5 0.0 58.1 0.6 3.7 0.0 0.0 0.0 0.9 0.9 18.0 1.0 1.3 0.2 0.1 0.0 0.9 309.0 2.2 23.7 2.6 2.5 6.5 0.6 0.3 1.2 503.1 3.0 0.8 CACNB2 "CACNLB2, MYSB" ENSG00000165995 "Calcium voltage-gated channel auxiliary subunit beta 2" Q08289 10 18140424-18543557 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.1" "Group enriched" "Detected in many" 5 "Astrocytes: 863.5;Excitatory neurons: 545.7;Inhibitory neurons: 357.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HAP1: 6.4;HSkMC: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035326 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA035326: AB_10669903" "unprognostic (3.03e-3)" "unprognostic (3.04e-1)" "unprognostic (1.49e-2)" "unprognostic (1.16e-1)" "unprognostic (4.58e-3)" "unprognostic (4.67e-4)" "unprognostic (8.03e-2)" "unprognostic (3.76e-2)" "unprognostic (8.10e-2)" "unprognostic (1.70e-1)" "unprognostic (7.78e-4)" "unprognostic (1.40e-1)" "prognostic favorable (3.56e-5)" "unprognostic (3.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.03e-1)" "unprognostic (8.16e-2)" 2.8 9.4 1.3 2.1 3.9 1.3 3.8 5.4 12.9 7.4 0.1 17.6 1.1 12.8 2.7 5.0 10.1 2.2 17.8 5.4 7.4 3.2 10.7 3.9 0.9 0.0 0.1 13.6 7.5 0.6 19.3 0.5 0.0 8.5 3.2 35.1 3.9 8.8 1.1 4.2 11.4 5.3 0.0 1.5 7.7 2.1 2.2 0.7 2.5 0.7 0.2 16.8 4.6 1.5 0.2 1.0 0.7 0.5 0.3 0.3 0.5 0.3 0.0 0.0 0.3 0.4 0.5 0.9 0.2 0.2 0.3 0.7 6.4 0.0 0.0 0.3 2.4 0.8 1.7 1.5 1.6 0.5 1.5 8.1 0.0 0.0 0.0 0.3 0.0 1.4 0.9 1.6 0.0 0.7 0.8 1.0 2.4 0.0 0.0 0.7 0.7 0.8 0.0 0.8 2.9 0.8 0.1 0.0 0.4 0.8 0.1 0.9 0.0 0.6 1.5 0.3 0.6 1.6 1.8 1.7 0.2 1.2 0.3 1.4 0.1 0.2 0.2 0.2 0.4 0.4 0.3 0.1 0.0 0.5 0.5 0.8 0.1 0.3 0.2 0.2 1.1 0.0 1.3 3.9 5.4 12.9 5.4 7.4 0.0 0.1 0.0 0.0 2.2 1.5 2.1 0.0 0.6 863.5 0.1 3.3 1.3 0.0 1.8 31.9 1.1 1.3 22.4 0.0 0.0 0.0 108.4 0.4 0.7 2.8 1.9 0.4 0.9 1.1 13.9 1.5 37.1 0.8 545.7 0.2 0.0 3.0 0.0 2.6 0.0 3.8 0.0 0.9 0.1 8.4 357.8 9.4 0.0 0.0 1.1 0.8 0.9 0.5 1.8 96.5 0.0 15.9 0.0 95.5 13.7 0.2 2.4 4.5 0.3 2.1 5.9 0.8 0.0 75.7 6.6 2.6 14.2 0.1 0.1 0.0 4.1 0.3 1.0 5.3 5.7 1.3 CACNG1 CACNLG ENSG00000108878 "Calcium voltage-gated channel auxiliary subunit gamma 1" Q06432 17 67044554-67056797 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 55 "skeletal muscle: 327.7;tongue: 121.8" "Cell type enriched" "Detected in single" 27 "Skeletal myocytes: 8.1" "Cancer enhanced" "Detected in some" "breast cancer: 1.6;head and neck cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 2.9" "Region enriched" "Detected in single" 6 "basal ganglia: 3.4" "Not detected" "Not detected" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (1.76e-1)" "unprognostic (9.83e-3)" "unprognostic (1.75e-5)" "unprognostic (2.60e-1)" "unprognostic (6.72e-3)" "unprognostic (2.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.84e-3)" "unprognostic (1.07e-1)" "unprognostic (4.20e-2)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (3.03e-1)" "unprognostic (1.94e-1)" 0.0 1.6 0.6 0.0 0.7 0.0 0.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 3.3 0.0 327.7 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.6 0.0 121.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.1 0.6 0.3 0.2 0.2 0.2 0.2 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CALHM2 FAM26B ENSG00000138172 "Calcium homeostasis modulator family member 2" Q9HA72 10 103446786-103452402 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 75.1;Fibroblasts: 38.2;Hepatic stellate cells: 48.2;Hofbauer cells: 53.7;Leydig cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 45.1;BJ: 37.7;BJ hTERT+: 37.5;fHDF/TERT166: 43.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014706 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" Cytosol "HPA014706: AB_2243916" "unprognostic (2.45e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (2.48e-1)" "unprognostic (3.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (8.85e-2)" "unprognostic (5.78e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (8.59e-2)" "unprognostic (2.47e-1)" "unprognostic (3.56e-1)" "unprognostic (4.74e-1)" 49.7 18.5 7.2 12.5 6.5 2.1 38.9 6.3 9.0 54.4 7.0 18.4 6.5 58.1 5.5 12.2 43.3 21.6 34.2 7.0 7.3 10.7 4.5 23.2 13.7 8.0 6.4 48.1 7.1 3.1 7.3 10.0 7.8 21.1 4.3 0.4 14.9 10.6 9.7 17.9 19.6 15.9 7.7 35.3 13.8 11.5 8.0 5.6 21.6 11.1 6.1 33.9 39.3 7.9 11.0 7.5 1.8 2.4 27.3 45.1 9.1 37.7 37.5 11.2 15.7 3.3 5.3 3.3 4.2 43.2 0.7 5.0 3.8 0.0 2.1 0.4 21.5 7.8 2.5 0.6 12.4 1.3 0.7 15.6 0.0 3.3 0.1 20.8 13.5 8.3 1.8 19.8 7.5 25.0 3.0 3.7 4.8 2.3 6.7 9.2 3.0 7.5 1.0 0.9 5.3 2.3 1.5 6.2 2.1 0.8 1.2 2.5 24.5 3.6 4.4 12.6 2.7 3.0 7.6 3.8 31.0 24.0 0.8 70.0 91.9 1.8 83.7 178.4 69.6 27.7 56.5 69.7 152.1 7.3 10.8 42.3 3.6 62.9 214.6 17.8 82.7 85.6 7.2 6.5 6.3 9.0 7.0 7.3 8.0 6.4 7.8 7.7 8.0 7.9 18.2 3.2 0.6 1.0 4.9 5.4 2.9 0.6 4.0 0.1 3.4 4.4 3.3 1.5 0.0 3.7 0.0 3.1 11.3 0.1 0.0 4.2 1.0 1.4 19.8 25.5 1.2 5.7 2.3 0.2 75.1 38.2 1.5 2.1 8.8 11.4 48.2 0.6 53.7 0.0 0.5 0.1 2.0 28.8 18.8 2.5 45.7 21.5 8.8 2.8 17.3 0.2 33.0 1.0 0.2 0.1 0.1 16.1 3.1 0.8 0.0 0.3 0.0 0.1 19.7 16.8 27.9 0.8 0.9 0.8 3.8 19.2 19.4 6.0 0.0 1.0 CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113451032-113761927 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 159.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 272.9;Excitatory neurons: 182.9;Inhibitory neurons: 200.0;Microglial cells: 187.4;Oligodendrocyte precursor cells: 203.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 272.6" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 240000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions, Cytosol" "HPA026281: AB_1845944, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (2.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.13e-1)" "unprognostic (7.49e-2)" "unprognostic (2.19e-1)" "unprognostic (5.09e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "unprognostic (7.81e-2)" "unprognostic (7.91e-3)" "unprognostic (2.62e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-2)" "unprognostic (1.87e-1)" "unprognostic (1.90e-2)" 28.6 25.6 52.7 26.6 45.1 5.7 21.0 45.8 52.0 18.9 1.6 36.4 28.8 23.5 9.8 29.7 18.8 30.7 159.3 60.2 23.9 19.3 37.3 22.9 35.2 11.8 33.9 25.4 15.2 56.5 9.1 19.8 12.6 32.2 39.1 79.2 13.4 41.7 105.1 15.8 34.1 24.9 21.0 18.4 37.1 19.8 46.7 16.3 23.7 60.0 31.4 27.4 19.7 22.9 4.8 62.5 67.5 22.8 144.0 272.6 24.0 145.4 96.3 56.0 48.0 42.3 17.6 91.2 20.7 102.3 70.7 2.1 42.6 22.8 56.6 35.1 10.8 0.0 22.0 49.2 73.0 0.1 0.2 176.3 30.5 43.5 107.1 88.5 50.6 11.3 3.6 39.4 106.8 17.1 9.3 3.6 9.8 60.3 22.8 17.9 79.0 0.4 57.3 42.7 18.2 18.3 20.0 29.3 19.5 55.9 0.6 23.7 30.7 146.9 34.8 63.6 29.1 30.4 16.5 76.7 75.7 5.5 70.8 0.0 12.7 0.0 6.7 7.0 12.7 11.2 6.6 7.5 15.7 22.6 7.4 6.5 0.9 9.7 2.5 0.1 13.2 7.7 52.7 45.1 45.8 52.0 60.2 23.9 11.8 33.9 12.6 21.0 46.7 22.9 43.7 41.7 37.6 128.3 55.1 18.4 16.6 8.3 22.8 83.3 14.0 17.1 272.9 62.9 24.7 29.5 87.6 0.5 19.0 70.9 5.9 8.4 3.2 18.2 35.2 27.2 103.8 3.6 182.9 20.1 0.4 50.1 71.9 47.0 10.1 13.0 24.3 57.2 18.6 72.3 200.0 88.1 14.2 17.3 22.3 6.2 20.2 31.5 5.4 187.4 16.0 35.9 28.8 203.1 128.0 11.6 57.3 19.9 20.4 36.2 52.4 23.1 21.7 74.0 6.6 32.8 44.4 3.1 3.4 37.1 31.8 1.1 27.8 12.3 48.6 27.5 CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1056.7" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 777.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "HSkMC: 13.6" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in all" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027285: AB_1845933, HPA055298: AB_2682777" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (9.70e-3)" "unprognostic (1.28e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.03e-4)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (7.20e-3)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.25e-5)" 31.9 3.0 3.5 6.4 2.3 0.0 8.9 2.8 4.0 8.0 2.0 59.8 3.3 17.2 6.5 38.5 14.7 6.6 1056.7 1.8 3.6 3.5 0.6 5.3 0.8 1.9 4.8 5.3 1.2 1.6 0.9 1.6 2.1 13.8 17.0 0.3 7.6 20.2 182.1 4.9 9.1 39.1 1.9 0.8 14.2 1.5 6.4 1.6 4.1 165.0 1.3 43.9 6.9 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 2.3 2.8 4.0 1.8 3.6 1.9 4.8 2.1 1.9 6.4 1.9 2.7 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.6 0.2 0.1 0.4 777.8 0.0 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 15.5 0.3 0.0 4.8 0.0 0.0 0.7 0.0 0.3 17.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 20.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 1.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 92.1 11.0 73.4 0.1 0.4 0.2 0.3 0.0 0.1 0.0 0.0 0.0 CBX6 ENSG00000183741 "Chromobox 6" O95503 22 38861422-38872249 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048653 Uncertain Approved Nucleoplasm,Mitochondria NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Mitochondria" "HPA048653: AB_2680479" "unprognostic (1.65e-2)" "unprognostic (8.66e-2)" "unprognostic (6.20e-3)" "unprognostic (3.14e-3)" "unprognostic (1.56e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.90e-2)" "unprognostic (3.72e-3)" "unprognostic (5.97e-2)" "prognostic favorable (2.46e-6)" "unprognostic (2.75e-1)" "unprognostic (1.27e-3)" "unprognostic (7.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.94e-1)" "unprognostic (2.26e-2)" 16.3 22.4 67.1 16.5 53.6 28.3 12.3 9.9 83.6 21.0 0.0 39.3 6.5 34.0 14.5 13.3 27.0 11.3 17.7 88.2 10.1 18.7 6.3 17.2 14.2 16.6 14.0 24.4 17.1 49.5 27.5 4.3 10.0 22.0 7.2 8.5 13.7 25.9 8.9 8.2 17.1 26.1 5.5 15.9 20.5 4.3 21.8 12.5 19.0 6.7 15.3 31.0 11.9 30.8 40.3 41.7 9.1 31.3 68.5 38.2 2.8 42.8 24.5 21.8 20.3 21.1 36.5 65.3 31.2 29.5 15.3 46.8 17.0 18.3 11.9 63.1 53.0 6.7 18.5 7.4 37.2 32.6 31.1 57.0 9.1 49.7 23.5 30.1 24.9 18.4 14.9 32.2 15.1 45.5 20.2 9.5 8.1 23.1 31.9 29.9 30.5 25.9 31.3 37.4 44.3 9.8 27.5 36.4 23.7 3.2 25.0 19.3 32.7 18.9 57.9 33.2 29.6 32.9 34.1 23.5 37.0 33.6 40.1 2.2 9.1 4.7 18.6 12.4 15.3 6.7 12.6 13.1 9.1 7.7 10.3 12.6 4.0 9.1 12.5 46.1 8.0 20.0 67.1 53.6 9.9 83.6 88.2 10.1 16.6 14.0 10.0 5.5 21.8 30.8 30.5 16.0 14.7 9.8 25.1 33.9 47.4 18.4 16.5 100.4 42.6 31.6 27.5 52.9 22.1 73.5 39.6 12.4 83.0 9.6 35.2 102.6 1.1 6.9 46.0 36.4 122.7 17.7 28.9 50.1 2.0 48.5 3.1 17.5 6.3 18.7 46.8 32.4 19.8 124.5 27.3 3.2 30.5 40.8 121.1 2.9 74.3 33.2 81.8 14.0 91.1 91.2 57.7 15.1 23.3 46.9 9.1 80.9 24.5 58.9 0.1 51.7 18.0 59.4 72.3 54.4 85.1 4.2 6.8 10.4 34.0 4.7 35.8 40.9 0.9 82.6 CCDC144A "FLJ43983, KIAA0565" ENSG00000170160 "Coiled-coil domain containing 144A" A2RUR9 17 16689537-16777881 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 9.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.2;Early spermatids: 59.1;Rod photoreceptor cells: 49.4;Spermatocytes: 165.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "basal ganglia: 2.4;cerebellum: 7.6;cerebral cortex: 6.9;hippocampal formation: 4.9;white matter: 3.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.5;TIME: 8.5" "HPA022996, HPA047220, HPA047851, HPA066260" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 6: Brain - Smell perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA022996: AB_1846136, HPA047220: AB_2679989, HPA047851: AB_2680182, HPA066260: " "unprognostic (8.54e-2)" "unprognostic (4.49e-3)" "unprognostic (1.07e-1)" "unprognostic (8.34e-2)" "unprognostic (1.10e-1)" "unprognostic (2.18e-2)" "unprognostic (1.57e-1)" "unprognostic (5.69e-2)" "unprognostic (6.95e-2)" "unprognostic (2.60e-2)" "unprognostic (2.73e-1)" "unprognostic (1.43e-1)" "unprognostic (2.54e-1)" "unprognostic (9.49e-2)" "unprognostic (3.32e-1)" "unprognostic (1.41e-1)" "unprognostic (1.74e-1)" 1.3 1.3 0.6 2.1 2.4 4.2 1.5 7.6 6.9 1.1 0.0 1.7 0.7 3.5 2.5 0.8 1.6 1.2 1.2 4.9 0.0 0.5 1.1 1.3 1.7 0.8 0.0 4.5 2.7 0.4 1.6 2.7 0.8 1.5 0.9 7.4 1.2 1.0 1.0 2.5 1.0 1.6 0.0 1.8 1.5 9.1 0.0 3.3 0.8 2.3 1.2 1.6 0.9 3.9 0.5 3.4 0.8 2.1 3.0 9.5 0.4 0.2 0.0 0.2 0.2 4.4 0.1 0.5 2.8 6.2 0.2 5.3 4.4 0.3 0.2 3.2 0.2 0.4 0.5 0.3 0.2 0.7 2.7 1.7 0.1 2.1 0.2 0.9 0.1 0.1 0.4 0.3 2.0 0.1 0.0 1.1 0.6 0.9 0.4 1.4 0.2 0.1 0.1 4.1 1.1 1.2 0.6 0.2 1.2 1.5 3.4 0.1 8.5 0.7 0.4 4.6 1.4 5.7 6.3 0.2 0.3 6.2 1.6 0.2 0.1 0.0 0.5 0.1 0.3 0.2 0.5 0.3 0.1 0.1 0.9 0.5 0.2 0.2 0.4 0.2 0.5 0.0 0.6 2.4 7.6 6.9 4.9 0.0 0.8 0.0 0.8 0.0 0.0 3.9 5.9 0.0 14.9 15.7 3.1 4.0 6.4 1.9 0.0 40.8 4.5 2.5 2.8 2.8 2.9 0.0 54.2 4.9 6.4 1.7 0.0 1.8 59.1 8.0 25.8 9.1 1.2 1.7 21.2 0.0 7.1 9.7 2.0 10.4 26.0 6.2 3.6 2.0 4.2 33.7 19.8 2.4 2.0 6.8 7.7 6.5 7.2 6.3 5.4 1.0 3.6 7.1 6.2 17.1 4.0 1.7 3.8 9.1 1.7 8.6 1.2 1.1 3.9 49.4 6.6 11.7 10.2 165.9 36.1 0.2 3.7 1.9 6.9 22.2 2.1 4.6 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCDC93 FLJ10996 ENSG00000125633 "Coiled-coil domain containing 93" Q567U6 2 117915478-118014133 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054183 Approved Enhanced "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA054183: AB_2682408" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" "unprognostic (8.29e-2)" "unprognostic (1.02e-2)" "unprognostic (3.32e-2)" "unprognostic (2.47e-3)" "prognostic unfavorable (2.97e-6)" "unprognostic (2.51e-1)" "unprognostic (8.12e-2)" "unprognostic (8.99e-2)" "unprognostic (1.52e-3)" "unprognostic (8.56e-2)" "unprognostic (4.87e-1)" "unprognostic (1.79e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (9.66e-4)" "unprognostic (2.40e-2)" 10.2 14.5 9.3 10.4 8.5 21.7 9.6 9.6 12.7 9.1 15.0 11.3 11.9 8.2 9.8 7.4 9.3 7.1 21.3 8.4 9.4 9.8 7.8 11.8 10.3 9.7 9.0 13.3 13.0 15.9 16.1 8.1 10.3 7.6 10.6 26.0 9.1 8.4 12.9 11.0 12.8 8.1 8.4 12.1 9.1 12.1 11.5 10.1 11.9 10.3 10.1 8.6 8.1 8.5 18.7 8.1 22.0 19.4 31.2 21.3 18.5 21.8 14.2 14.0 14.3 17.7 11.7 15.9 14.5 17.1 24.9 15.8 12.8 11.2 18.1 20.8 13.0 20.1 15.5 23.9 13.7 22.1 22.0 14.6 11.5 21.9 25.9 19.4 15.0 18.9 11.1 11.0 15.8 8.1 14.0 23.8 9.9 13.4 13.0 17.6 17.2 10.7 11.5 19.6 17.4 10.3 14.2 10.6 15.1 19.6 8.9 13.5 21.2 23.9 20.0 20.4 15.3 14.3 16.0 24.7 13.8 16.1 14.2 2.9 1.6 1.8 2.1 2.1 2.0 1.6 1.5 1.8 1.2 1.4 2.0 1.7 1.7 1.7 1.3 0.5 0.7 1.0 9.3 8.5 9.6 12.7 8.4 9.4 9.7 9.0 10.3 8.4 11.5 8.5 17.4 19.2 28.2 61.0 28.6 17.6 14.6 11.2 9.6 32.0 12.4 10.0 43.0 7.2 17.5 1.8 47.9 12.6 31.9 21.5 9.8 24.0 4.5 14.9 15.2 16.5 16.7 9.9 57.1 16.7 8.5 14.7 11.7 17.0 15.2 25.1 12.8 6.0 15.2 20.2 60.6 11.4 10.2 16.3 15.9 10.6 13.7 19.9 3.6 32.8 19.9 13.8 20.6 53.3 37.9 32.0 11.9 14.3 19.4 13.9 17.1 9.4 16.3 36.0 6.6 21.4 15.0 46.0 31.1 10.1 16.1 12.9 24.3 12.8 14.0 15.0 CCL13 "CKb10, MCP-4, MGC17134, NCC-1, SCYA13, SCYL1" ENSG00000181374 "C-C motif chemokine ligand 13" Q99616 17 34356480-34358610 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.4;urinary bladder: 30.4" "Cell type enhanced" "Detected in some" "Hofbauer cells: 48.7;Langerhans cells: 81.2;Melanocytes: 17.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.8;BJ hTERT+: 1.7;BJ hTERT+ SV40 Large T+ RasG12V: 1.0;HMC-1: 1.3;HSkMC: 1.7" "Secreted to blood" NA NA 336000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "unprognostic (2.22e-2)" "unprognostic (3.56e-2)" "unprognostic (8.41e-3)" "unprognostic (1.49e-3)" "unprognostic (4.43e-2)" "unprognostic (1.58e-1)" "unprognostic (7.58e-2)" "unprognostic (8.49e-2)" "unprognostic (1.18e-1)" "unprognostic (2.83e-2)" "unprognostic (1.35e-2)" "unprognostic (5.98e-2)" "unprognostic (8.63e-8)" "unprognostic (2.26e-1)" "unprognostic (2.57e-1)" "unprognostic (1.37e-1)" "unprognostic (1.71e-2)" 24.0 4.5 0.0 7.0 0.0 0.3 18.4 0.0 0.5 3.2 0.0 30.4 21.3 0.6 0.3 11.9 4.4 2.7 11.8 0.0 0.0 1.7 0.2 22.5 3.2 0.0 0.0 0.3 0.7 1.6 0.1 9.7 0.0 1.6 25.1 0.0 2.6 0.8 0.6 4.5 27.0 9.0 0.0 0.1 2.9 2.4 0.0 8.7 1.8 5.8 1.8 30.4 3.2 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.2 1.7 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.2 0.0 0.0 0.0 8.8 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.4 7.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 81.2 0.3 0.0 6.6 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.0 0.0 0.1 4.7 0.3 1.0 0.0 0.0 0.1 CCL8 "HC14, MCP-2, SCYA8" ENSG00000108700 "C-C motif chemokine ligand 8" P80075 17 34319435-34321402 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Smooth muscle cells: 104.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 6 "monocytes: 3.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.1;BJ hTERT+ SV40 Large T+ RasG12V: 1.0;EFO-21: 2.1;HSkMC: 3.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 32000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (7.51e-2)" "unprognostic (3.20e-1)" "unprognostic (1.90e-2)" "unprognostic (4.03e-2)" "unprognostic (8.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (9.97e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.05e-7)" "unprognostic (1.39e-1)" "unprognostic (1.88e-2)" "unprognostic (5.65e-2)" "unprognostic (3.41e-2)" 17.5 4.7 0.4 5.1 0.4 1.8 6.2 0.4 0.9 1.5 0.5 18.1 14.1 7.3 1.9 3.5 1.3 8.8 2.7 0.4 0.4 7.7 3.2 7.1 3.9 0.6 0.4 1.4 1.1 4.8 0.5 7.1 0.6 2.2 16.4 0.0 1.9 1.3 0.4 0.5 17.0 9.3 1.8 2.9 2.9 3.1 1.1 12.5 2.3 7.0 0.5 13.7 0.3 0.6 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.1 0.0 1.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.4 0.9 0.4 0.4 0.6 0.4 0.6 1.8 1.1 0.6 21.5 0.0 0.0 0.0 0.1 4.2 0.3 0.5 0.0 0.0 0.9 1.1 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 10.5 0.9 7.5 9.6 0.0 0.0 0.0 2.0 0.0 16.4 0.0 1.6 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 3.5 18.6 2.2 0.0 12.7 5.4 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.3 104.3 0.0 0.0 0.0 5.4 0.1 0.8 0.7 0.0 0.1 CD151 "PETA-3, RAPH, SFA-1, TSPAN24" ENSG00000177697 "CD151 molecule (Raph blood group)" P48509 11 832887-839831 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Blood group antigen" "Deafness, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 716.2;Exocrine glandular cells: 636.7;Pancreatic endocrine cells: 736.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002428, HPA011906" Supported NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "CAB002428: AB_564129, HPA011906: AB_1846245" "unprognostic (1.50e-1)" "unprognostic (1.12e-2)" "unprognostic (5.47e-2)" "unprognostic (5.45e-3)" "unprognostic (4.10e-3)" "unprognostic (2.45e-2)" "prognostic unfavorable (5.58e-4)" "prognostic unfavorable (9.46e-4)" "unprognostic (5.47e-2)" "unprognostic (2.41e-1)" "unprognostic (1.02e-3)" "unprognostic (3.31e-1)" "unprognostic (4.39e-2)" "unprognostic (6.23e-3)" "unprognostic (3.24e-1)" "prognostic favorable (6.92e-4)" "unprognostic (7.83e-2)" 332.4 159.5 54.0 79.7 53.5 25.0 277.8 52.5 67.6 181.6 66.1 219.7 140.6 264.6 103.0 97.5 184.3 132.4 345.8 54.2 65.3 194.3 145.3 240.1 35.4 64.5 57.4 116.2 278.3 85.9 81.1 110.1 60.5 182.9 99.8 9.6 243.5 194.2 113.1 107.0 149.4 255.2 58.3 94.8 187.3 44.8 58.6 15.0 133.5 77.0 30.6 203.1 151.3 58.0 380.0 475.3 71.8 256.3 1088.7 422.8 110.4 587.1 400.4 285.0 241.2 252.6 677.2 0.2 224.0 943.5 388.4 358.4 71.1 498.4 96.1 135.0 236.6 112.8 139.1 193.4 366.7 90.2 157.4 388.6 328.2 164.5 367.8 1089.2 348.8 16.4 135.1 56.3 485.9 196.1 1.9 99.5 48.0 232.9 569.4 20.0 173.7 106.4 642.8 102.1 99.5 111.8 578.9 371.5 121.5 81.6 145.8 102.4 600.0 462.6 209.3 147.5 352.9 62.0 66.5 4.5 437.5 89.7 265.8 24.6 19.1 15.2 5.7 19.3 6.8 3.0 4.7 5.0 11.9 2.0 1.9 3.0 7.3 8.2 24.1 1.8 2.9 10.8 54.0 53.5 52.5 67.6 54.2 65.3 64.5 57.4 60.5 58.3 58.6 58.0 294.4 208.3 79.1 13.1 12.8 70.6 143.2 328.2 60.9 16.6 180.9 203.7 180.0 133.0 159.8 248.3 4.2 222.6 15.6 542.3 19.6 716.2 2.6 60.8 114.6 214.8 127.6 28.6 10.0 636.7 423.8 173.8 236.5 143.7 81.3 103.7 265.2 54.0 130.0 37.0 5.5 388.5 138.4 59.3 70.4 11.3 123.6 81.8 128.1 15.9 75.6 94.8 23.7 3.5 0.7 736.6 477.9 283.2 26.6 307.1 440.6 124.6 52.2 17.0 210.4 96.6 310.3 5.6 13.6 73.4 54.4 185.7 29.7 61.1 289.8 199.6 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD302 "BIMLEC, CLEC13A, DCL-1, KIAA0022" ENSG00000241399 "CD302 molecule" Q8IX05 2 159768628-159798255 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 193.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 352.2;Kupffer cells: 382.4;Macrophages: 194.3;monocytes: 166.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 215 "dendritic cells: 24.4;granulocytes: 32.2;monocytes: 33.0" "Cell line enriched" "Detected in many" 5 "ASC diff: 246.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 110000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.52e-1)" "unprognostic (5.44e-2)" "unprognostic (1.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (6.88e-2)" "unprognostic (1.68e-2)" "unprognostic (9.12e-3)" "unprognostic (5.29e-3)" "unprognostic (2.37e-2)" "unprognostic (4.38e-2)" "unprognostic (2.14e-1)" "unprognostic (4.67e-3)" "unprognostic (1.75e-2)" "unprognostic (6.61e-2)" "unprognostic (7.45e-2)" "unprognostic (3.61e-3)" 49.4 25.5 6.5 15.5 6.6 30.6 31.0 7.1 9.2 34.6 10.6 16.8 24.1 21.8 14.2 11.7 15.0 30.7 13.3 6.1 7.5 16.9 193.8 50.0 11.7 8.8 7.2 41.9 17.6 10.9 3.2 19.4 8.5 21.3 20.7 2.1 12.0 20.4 2.9 6.2 28.1 22.5 7.5 31.3 15.7 9.0 6.6 9.7 31.1 17.3 9.9 24.6 13.3 8.5 0.1 1.4 1.2 0.0 246.9 51.5 0.0 5.3 25.9 7.4 10.9 1.6 2.2 0.4 2.0 13.5 7.8 0.0 5.5 3.0 10.1 1.6 8.6 7.0 1.3 3.6 12.3 18.6 6.0 41.2 1.4 8.0 0.0 6.0 18.9 0.0 0.6 5.8 9.5 0.6 0.0 13.1 2.4 0.0 6.7 0.0 1.8 0.2 1.6 0.2 2.7 2.9 1.8 5.9 5.7 3.8 4.8 18.3 4.1 13.7 0.0 0.2 4.1 0.5 0.0 0.0 9.9 1.5 3.1 13.5 33.0 32.2 0.0 24.1 0.0 0.1 0.0 0.0 24.4 0.1 0.0 0.0 29.2 0.1 26.1 6.8 0.0 12.5 6.5 6.6 7.1 9.2 6.1 7.5 8.8 7.2 8.5 7.5 6.6 8.5 28.0 44.8 111.9 0.0 5.0 6.6 15.9 2.4 16.5 3.3 20.2 15.2 3.9 31.5 26.5 3.7 0.0 2.5 19.3 3.7 0.0 4.0 31.7 3.0 38.7 25.3 9.6 21.0 0.0 3.5 10.5 80.5 20.4 3.0 30.9 26.7 65.7 352.2 42.7 3.3 0.0 25.2 0.0 382.4 97.3 16.4 122.7 194.3 19.6 0.0 166.6 2.1 2.1 0.0 0.0 2.3 12.2 93.6 3.5 13.9 19.6 4.1 17.1 2.4 65.7 24.8 30.7 27.9 11.6 3.6 4.4 2.7 6.5 8.6 22.7 10.4 CD36 "FAT, GP3B, GP4, GPIV, SCARB3" ENSG00000135218 "CD36 molecule" P16671 7 80369575-80679277 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Transport" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1533.6" "Cell type enhanced" "Detected in many" "Adipocytes: 3219.2;Cardiomyocytes: 623.1;Hofbauer cells: 1369.8;Sertoli cells: 696.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 962.6;intermediate monocyte: 270.6;myeloid DC: 507.1" "Group enriched" "Detected in all" 46 "dendritic cells: 507.1;monocytes: 962.6" "Group enriched" "Detected in some" 4 "ASC diff: 322.6;HEL: 158.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 16.9" "HPA002018, CAB025866, HPA071026" Enhanced Enhanced "Golgi apparatus" NA NA 5300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB025866: , HPA002018: AB_1078464, HPA071026: AB_2732170" "unprognostic (7.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.06e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (9.35e-2)" "unprognostic (2.64e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.84e-3)" "prognostic unfavorable (4.47e-4)" "unprognostic (7.05e-3)" "unprognostic (4.87e-2)" "unprognostic (2.73e-3)" 1533.6 24.6 3.4 51.7 2.5 148.2 540.4 1.6 2.0 11.6 2.7 40.5 113.6 8.7 38.2 19.6 40.5 84.0 540.9 2.6 6.9 7.0 80.8 131.2 18.8 22.0 21.2 4.0 31.2 25.0 2.0 413.3 15.7 5.0 40.9 0.3 31.9 8.6 248.5 28.6 119.7 39.4 14.0 309.9 31.2 7.7 24.0 22.1 69.1 381.6 7.2 22.2 13.4 3.9 0.0 0.0 1.0 0.2 322.6 3.3 0.7 0.9 10.7 0.1 0.1 0.0 0.0 0.1 0.6 1.4 0.3 0.1 4.3 0.5 0.1 0.6 0.4 158.1 0.5 25.7 0.2 0.1 0.1 31.0 12.6 0.1 0.2 7.7 0.9 0.0 5.8 0.0 1.8 0.2 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.5 0.5 0.1 0.9 1.3 0.8 0.6 0.3 2.7 11.1 19.3 0.4 0.5 0.5 0.6 0.3 0.2 0.8 0.4 0.1 54.3 41.8 12.3 962.6 3.7 1.9 270.6 2.1 3.6 0.6 0.6 507.1 0.5 0.8 0.4 15.8 5.9 72.0 128.3 1.5 692.4 3.4 2.5 1.6 2.0 2.6 6.9 22.0 21.2 15.7 14.0 24.0 3.9 3219.2 6.4 63.1 0.0 7.9 7.4 0.2 3.0 0.6 0.2 189.9 24.8 623.1 4.3 9.8 7.3 0.0 10.1 55.0 0.0 0.0 0.2 11.7 5.0 5.9 303.3 0.0 419.5 6.3 0.0 11.1 69.6 1.1 38.4 15.2 0.6 406.2 9.0 1369.8 0.0 2.2 0.6 8.2 153.7 67.3 3.9 0.6 159.6 16.0 17.8 255.2 0.0 7.2 0.5 1.3 0.1 0.0 0.0 4.2 0.8 9.9 0.4 1.2 0.3 696.8 33.1 452.1 4.6 0.7 0.8 4.7 18.3 5.9 1.9 0.2 0.3 CD81 "TAPA-1, TAPA1, TSPAN28" ENSG00000110651 "CD81 molecule" P60033 11 2376177-2397397 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 1003.1;Endometrial stromal cells: 1050.9;Muller glia cells: 809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 148.9;naive B-cell: 137.2" "Lineage enriched" "Detected in all" 4 "B-cells: 148.9" "Cell line enhanced" "Detected in many" "ASC diff: 2960.6;fHDF/TERT166: 1752.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002507, HPA007234" Supported Supported "Plasma membrane,Cytosol" NA NA 400000 "Cluster 43: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Cytosol "CAB002507: AB_563639, HPA007234: AB_1846333" "unprognostic (2.96e-1)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.21e-5)" "unprognostic (6.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.07e-3)" "unprognostic (2.08e-1)" "unprognostic (3.55e-2)" "unprognostic (1.67e-1)" "unprognostic (2.06e-1)" "unprognostic (2.06e-1)" 892.1 299.1 560.6 270.7 598.4 77.8 773.6 614.8 590.2 952.7 498.9 992.0 150.7 1384.0 960.5 364.3 853.1 534.5 937.9 511.1 615.8 636.6 1175.7 768.4 429.0 665.7 640.8 656.8 449.5 258.3 409.1 441.0 651.1 634.0 234.4 75.9 531.1 1602.0 214.3 511.1 423.1 978.5 694.1 631.3 494.3 316.9 655.1 158.9 564.6 227.6 278.6 749.2 763.4 734.4 337.0 342.0 268.5 413.4 2960.6 1668.4 224.8 621.0 1361.6 490.3 492.2 322.8 1.8 285.4 218.3 1752.6 312.5 430.5 167.3 442.2 199.9 135.6 517.8 43.7 117.1 0.3 976.4 188.2 359.8 1222.3 619.9 201.1 302.1 757.9 476.6 204.0 198.7 484.9 696.4 257.2 160.7 239.1 324.4 304.7 274.2 324.7 135.5 183.3 529.1 223.3 288.8 319.2 198.4 514.4 383.8 214.3 171.0 337.8 641.3 249.0 181.6 471.2 216.6 356.9 88.1 529.1 361.3 111.0 435.0 0.9 3.3 22.9 21.1 5.8 34.4 148.9 14.9 33.0 2.6 137.2 9.2 16.9 1.0 14.7 7.3 7.7 12.0 10.7 560.6 598.4 614.8 590.2 511.1 615.8 665.7 640.8 651.1 694.1 655.1 734.4 1003.1 243.6 270.0 95.0 88.2 179.8 391.8 89.7 26.2 82.7 325.6 452.0 277.4 167.3 102.3 207.8 27.1 21.8 267.1 20.0 35.2 105.7 15.9 365.4 1050.9 344.5 71.9 30.7 19.0 55.1 31.7 560.4 21.4 462.7 81.7 204.0 293.4 603.9 251.5 148.0 32.4 48.2 50.8 232.7 179.7 50.2 389.2 277.6 151.2 60.0 23.0 809.2 45.3 145.8 93.6 61.3 14.7 251.3 50.7 147.6 5.0 29.9 85.8 76.1 118.3 356.9 423.6 15.6 19.4 30.6 164.9 20.1 136.8 379.0 41.5 298.1 CD99 MIC2 ENSG00000002586 "CD99 molecule (Xg blood group)" P14209 X 2691187-2741309 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1614.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000020, HPA035304" Supported Approved "Golgi apparatus" NA NA 62000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "CAB000020: AB_2076419, HPA035304: AB_10672861" "unprognostic (3.71e-3)" "unprognostic (2.90e-1)" "unprognostic (5.97e-3)" "unprognostic (7.01e-3)" "unprognostic (2.14e-2)" "unprognostic (6.98e-3)" "unprognostic (3.89e-3)" "unprognostic (1.54e-2)" "unprognostic (1.06e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-2)" "unprognostic (1.87e-1)" "prognostic unfavorable (5.87e-7)" "unprognostic (2.11e-2)" "unprognostic (2.18e-1)" "unprognostic (5.37e-2)" "unprognostic (3.61e-2)" 476.3 143.3 132.0 119.2 142.1 105.4 327.7 148.8 135.4 367.4 126.5 353.2 148.5 305.5 132.4 208.8 249.4 264.5 343.7 128.8 247.5 112.7 227.7 256.5 146.6 210.9 178.1 303.0 234.6 46.8 132.9 194.8 216.8 270.3 152.9 15.1 184.2 258.4 163.7 284.7 210.0 226.1 224.4 186.0 209.1 199.6 139.4 562.1 152.6 168.3 129.2 296.3 314.6 227.6 259.4 276.5 308.5 424.8 1217.7 939.2 195.0 681.6 1050.1 419.2 604.8 412.3 179.1 18.3 130.0 929.4 217.5 99.4 124.1 168.4 337.5 350.8 321.2 53.1 179.5 353.4 390.1 81.7 375.0 580.1 204.9 223.7 155.6 271.8 766.4 256.3 66.4 0.9 391.9 191.2 672.3 266.8 107.5 28.6 310.0 118.7 273.2 513.5 240.7 165.4 1.0 141.2 168.7 138.2 432.6 744.9 129.6 229.4 750.2 509.7 86.1 487.1 230.2 1.0 0.8 116.1 338.1 203.1 323.8 23.6 526.0 18.3 1089.2 131.2 620.5 340.1 730.3 961.1 496.5 231.8 267.4 549.7 45.1 377.3 32.3 682.1 833.7 1421.2 132.0 142.1 148.8 135.4 128.8 247.5 210.9 178.1 216.8 224.4 139.4 227.6 297.7 64.1 68.3 20.5 172.0 250.6 207.4 274.4 138.9 5.1 66.9 48.3 86.6 112.9 88.4 71.7 0.0 223.6 507.7 68.4 13.7 145.3 8.8 180.2 279.7 387.7 80.8 136.5 0.9 138.4 189.7 604.7 116.7 188.8 230.4 1614.3 512.9 123.0 799.8 0.0 1.1 150.8 54.9 187.4 579.9 26.4 645.2 342.4 691.9 37.5 175.9 52.0 632.4 1.0 0.9 139.9 158.2 511.2 300.2 385.8 230.9 63.3 117.5 3.2 341.8 231.1 351.9 16.4 56.9 147.9 222.9 123.0 468.9 403.2 262.3 307.0 CD99L2 "CD99B, MIC2L1" ENSG00000102181 "CD99 molecule like 2" Q8TCZ2 X 150766336-150898816 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 179.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.1;Horizontal cells: 52.2;Inhibitory neurons: 57.2;Oligodendrocytes: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038782, HPA038783, HPA061400" Enhanced Supported "Plasma membrane" NA NA 1200000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA038782: AB_10795139, HPA038783: AB_10794734, HPA061400: AB_2732660" "unprognostic (2.10e-2)" "unprognostic (2.62e-3)" "unprognostic (3.12e-3)" "unprognostic (6.03e-3)" "unprognostic (1.22e-1)" "unprognostic (2.66e-1)" "unprognostic (5.56e-2)" "prognostic favorable (4.96e-4)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.74e-5)" "unprognostic (5.50e-2)" "unprognostic (5.13e-2)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (9.23e-2)" "prognostic unfavorable (8.74e-4)" 46.1 28.1 68.5 14.8 69.5 7.3 29.7 71.0 99.6 33.4 26.8 40.1 10.0 39.9 24.5 14.5 30.5 19.2 61.6 69.9 80.4 24.9 47.3 25.2 13.2 104.7 77.9 38.9 18.7 14.6 23.8 21.5 107.2 25.8 10.6 43.4 14.8 32.6 179.1 13.4 19.2 32.4 71.5 26.9 21.8 11.2 91.6 14.5 16.8 99.2 10.7 29.4 21.0 80.2 8.1 79.8 29.5 36.9 153.3 95.2 8.7 65.2 76.1 32.3 46.3 5.5 10.2 29.3 154.0 114.6 24.2 13.0 40.4 44.4 26.6 68.5 31.9 12.7 17.8 8.2 41.2 21.4 23.3 90.3 14.5 24.0 45.4 50.3 38.6 22.4 8.9 74.9 41.1 17.3 18.9 31.1 12.4 6.9 42.7 18.8 24.2 40.5 31.7 5.4 38.9 19.9 25.8 21.9 29.6 21.6 6.2 36.6 45.8 47.5 14.4 62.2 48.0 62.6 112.3 28.3 59.6 42.3 36.4 7.3 8.6 5.9 6.2 7.6 5.4 4.5 5.8 6.3 8.1 4.8 5.5 6.0 2.1 7.2 12.5 5.8 4.4 7.0 68.5 69.5 71.0 99.6 69.9 80.4 104.7 77.9 107.2 71.5 91.6 80.2 14.1 16.0 7.8 21.5 8.2 3.1 2.3 3.6 4.6 26.8 3.7 3.2 42.8 11.5 6.4 12.9 18.8 10.1 7.4 2.0 5.9 4.4 0.3 5.6 10.1 13.8 8.4 6.5 49.1 5.3 3.9 15.9 7.1 3.6 7.6 12.6 17.2 26.6 10.2 52.2 57.2 2.9 8.2 16.4 6.8 2.8 20.8 8.6 10.6 23.4 8.1 18.2 2.1 21.6 60.7 3.6 3.1 30.1 12.5 3.4 5.3 11.3 5.0 18.7 0.0 15.9 12.0 2.8 4.9 3.3 1.3 13.5 6.4 11.8 3.3 1.3 CDADC1 NYD-SP15 ENSG00000102543 "Cytidine and dCMP deaminase domain containing 1" Q9BWV3 13 49247925-49293485 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 174.6;Late spermatids: 77.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 9.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047615, HPA058314" Uncertain Approved Nucleoplasm No No "Cluster 18: Basophils - Vesicular transport" "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA047615: AB_2680104, HPA058314: AB_2683677" "unprognostic (2.81e-1)" "unprognostic (2.64e-1)" "unprognostic (2.20e-1)" "unprognostic (2.86e-1)" "unprognostic (2.75e-1)" "unprognostic (1.11e-2)" "unprognostic (1.58e-3)" "prognostic favorable (6.03e-4)" "unprognostic (7.68e-2)" "unprognostic (6.06e-2)" "unprognostic (2.35e-3)" "unprognostic (1.89e-1)" "prognostic favorable (1.19e-5)" "unprognostic (3.35e-2)" "unprognostic (5.92e-3)" "unprognostic (5.40e-2)" "unprognostic (8.27e-3)" 5.0 6.8 4.9 2.3 4.5 6.3 4.2 5.8 6.5 4.0 5.8 4.7 3.1 3.8 5.1 3.2 4.2 2.7 4.3 4.5 5.5 9.5 8.1 3.5 3.1 4.9 5.4 4.5 2.7 5.5 3.2 2.0 5.1 3.9 3.2 5.2 3.4 4.4 4.4 2.2 3.0 3.7 4.7 4.1 3.9 7.9 5.6 4.3 9.4 5.2 2.6 3.5 3.6 5.4 2.1 2.6 2.2 2.7 10.8 5.9 1.1 5.0 3.1 2.5 2.6 2.6 1.7 2.9 1.0 2.2 2.4 3.6 4.6 2.2 3.2 6.3 3.7 3.3 2.5 2.7 4.7 6.3 1.7 4.1 5.5 2.3 3.0 4.4 3.7 5.6 2.1 2.1 3.2 0.7 6.0 5.1 0.8 3.6 2.2 4.0 2.4 2.9 3.6 0.7 1.3 1.1 3.4 2.1 2.9 1.4 1.5 5.4 2.8 1.3 2.4 3.5 2.4 0.6 2.4 1.8 1.1 7.2 3.7 9.9 1.1 0.9 1.4 0.9 1.5 0.4 1.0 1.9 0.8 0.6 0.9 1.3 1.2 1.2 1.8 0.8 1.6 0.9 4.9 4.5 5.8 6.5 4.5 5.5 4.9 5.4 5.1 4.7 5.6 5.4 12.4 6.4 12.4 9.4 6.6 8.0 7.3 10.7 11.4 12.7 8.5 9.7 15.0 5.7 8.6 18.4 12.5 4.6 19.1 4.7 9.8 5.3 174.6 12.6 14.6 8.7 6.7 10.3 16.0 10.7 10.9 17.1 6.6 6.0 24.7 10.0 11.7 11.5 6.2 3.3 21.4 6.9 4.1 9.1 8.3 77.7 15.8 9.9 7.2 3.7 5.4 25.9 9.2 14.1 12.4 6.7 5.7 14.3 10.6 7.3 7.9 25.4 18.9 12.2 0.0 15.3 17.8 39.3 15.5 7.7 5.4 2.5 14.1 17.2 6.0 5.7 CDC14B "Cdc14B1, Cdc14B2, CDC14B3, hCDC14B" ENSG00000081377 "Cell division cycle 14B" O60729 9 96490241-96619843 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3" "Cell type enhanced" "Detected in many" "Astrocytes: 86.5;Excitatory neurons: 83.5;Inhibitory neurons: 110.2;Oligodendrocyte precursor cells: 156.9;Oligodendrocytes: 273.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 10.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064747 Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA064747: AB_2732719" "unprognostic (5.69e-2)" "unprognostic (9.09e-2)" "unprognostic (3.50e-2)" "unprognostic (8.08e-3)" "unprognostic (4.24e-1)" "unprognostic (1.19e-2)" "unprognostic (1.11e-2)" "unprognostic (4.49e-2)" "unprognostic (1.63e-2)" "unprognostic (2.27e-2)" "unprognostic (2.35e-1)" "unprognostic (2.75e-1)" "prognostic favorable (2.97e-10)" "unprognostic (2.01e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (7.40e-2)" 4.3 2.3 11.1 1.1 15.8 3.0 3.0 6.1 11.7 2.9 1.4 3.1 2.8 1.3 2.0 1.4 4.2 2.9 5.0 5.2 6.9 5.5 10.3 3.0 0.9 11.0 12.1 3.4 4.6 6.9 1.1 2.0 11.4 3.3 3.3 1.7 1.8 4.1 0.7 0.8 3.3 1.7 10.4 0.8 6.1 9.3 11.4 2.9 8.5 1.4 1.2 4.1 0.8 27.3 7.4 4.1 4.2 4.4 20.2 30.1 11.6 5.3 7.0 3.5 5.6 14.0 11.6 0.0 5.0 11.3 8.4 8.1 6.1 4.0 4.1 1.9 5.8 1.1 1.5 11.2 3.3 0.0 0.2 12.4 2.1 3.7 3.4 4.0 0.7 0.0 4.4 0.8 4.8 3.5 0.0 1.2 7.9 8.4 3.6 0.0 2.6 0.2 5.4 11.3 1.3 6.6 3.7 1.1 2.0 14.2 0.9 2.3 2.2 3.5 4.1 9.0 3.9 0.1 0.0 0.0 3.7 0.0 8.3 10.4 0.0 2.2 2.0 0.0 1.0 1.1 0.8 1.5 0.0 0.4 1.4 0.9 0.0 0.1 0.0 0.0 1.1 0.6 11.1 15.8 6.1 11.7 5.2 6.9 11.0 12.1 11.4 10.4 11.4 27.3 4.0 6.4 8.8 86.5 3.7 9.1 8.9 4.4 9.1 7.2 8.4 6.1 17.9 11.5 11.4 9.2 8.4 6.4 2.3 7.1 7.9 5.5 36.9 27.4 7.5 6.2 2.4 0.4 83.5 6.5 3.0 17.3 21.4 33.9 14.5 2.9 6.8 31.2 11.3 8.4 110.2 9.0 8.2 1.6 6.7 33.3 9.0 5.5 8.8 56.2 2.4 12.8 2.1 156.9 273.9 8.6 7.3 11.7 8.3 10.8 16.9 17.0 15.7 12.4 26.3 18.6 15.7 10.8 7.3 4.7 7.7 3.4 4.4 1.2 8.6 13.2 CDIPT "PIS, PIS1" ENSG00000103502 "CDP-diacylglycerol--inositol 3-phosphatidyltransferase" O14735 16 29858357-29863414 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056597 Enhanced Approved "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nuclear membrane, Plasma membrane" "HPA056597: AB_2683182" "unprognostic (7.81e-2)" "prognostic favorable (9.40e-4)" "unprognostic (1.93e-3)" "unprognostic (8.08e-3)" "unprognostic (1.50e-2)" "unprognostic (2.84e-2)" "unprognostic (7.60e-2)" "unprognostic (1.09e-2)" "unprognostic (7.03e-2)" "unprognostic (8.75e-2)" "unprognostic (5.56e-3)" "unprognostic (1.61e-1)" "unprognostic (6.17e-2)" "unprognostic (3.36e-2)" "unprognostic (6.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.48e-1)" 93.8 101.7 75.1 32.1 73.8 26.8 81.0 79.0 86.2 84.5 64.2 104.7 39.0 91.1 31.1 61.1 76.2 51.7 105.4 73.6 76.2 80.6 114.5 65.1 36.1 78.4 74.6 109.6 86.8 87.9 68.7 42.3 78.9 78.1 24.4 34.0 67.2 55.5 49.7 82.8 69.6 38.9 69.1 66.3 89.1 43.9 73.6 40.6 69.1 43.9 24.8 89.7 73.6 70.1 40.0 85.6 23.7 47.3 125.8 86.3 70.5 71.0 76.6 47.9 47.4 50.5 75.1 26.9 125.2 80.3 42.2 62.0 38.7 44.5 21.3 67.5 85.3 19.5 61.4 74.1 87.7 28.5 47.2 148.0 77.2 64.3 29.7 75.8 60.9 49.9 29.5 67.1 44.0 127.7 40.3 56.2 55.5 42.2 65.7 74.8 29.5 78.7 63.7 38.1 96.4 53.8 36.9 76.1 55.7 41.2 57.5 74.8 52.8 70.3 22.1 58.0 35.8 51.4 62.1 19.3 77.2 46.0 43.4 11.7 8.2 28.9 8.5 6.2 5.7 6.5 7.9 9.1 3.8 6.4 7.7 7.2 20.6 11.4 7.9 8.1 12.0 3.8 75.1 73.8 79.0 86.2 73.6 76.2 78.4 74.6 78.9 69.1 73.6 70.1 54.7 25.6 28.3 10.4 25.1 41.3 41.4 22.9 30.1 53.4 42.1 49.7 57.9 41.5 15.4 46.0 45.9 120.6 31.9 57.5 41.1 72.0 54.0 18.1 30.4 48.0 37.3 22.7 16.4 71.8 127.3 59.3 19.4 29.6 13.4 30.7 46.1 41.7 65.0 58.9 19.3 30.6 10.2 41.8 21.3 12.8 76.7 33.3 23.2 11.2 45.2 57.7 36.0 9.0 11.5 44.9 37.9 61.7 31.7 38.9 87.9 34.5 15.1 56.3 46.0 24.4 44.6 10.2 14.7 32.3 50.7 73.2 30.5 34.1 34.8 39.3 CDKL3 NKIAMRE ENSG00000006837 "Cyclin dependent kinase like 3" Q8IVW4 5 134286350-134371047 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.2" "Group enriched" "Detected in many" 6 "Early spermatids: 342.0;Late spermatids: 295.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027751 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Vesicles" "HPA027751: AB_10601256" "unprognostic (4.70e-2)" "unprognostic (2.15e-2)" "unprognostic (2.35e-1)" "unprognostic (1.48e-1)" "unprognostic (1.43e-1)" "unprognostic (3.98e-2)" "unprognostic (3.43e-3)" "unprognostic (5.93e-2)" "unprognostic (2.12e-3)" "unprognostic (1.49e-1)" "unprognostic (8.47e-4)" "unprognostic (2.82e-1)" "unprognostic (9.85e-4)" "unprognostic (8.33e-2)" "unprognostic (4.88e-2)" "unprognostic (7.10e-3)" "unprognostic (3.43e-3)" 0.7 0.8 2.5 0.5 2.8 0.2 0.6 2.5 4.4 0.8 1.3 0.8 0.5 1.1 0.6 0.6 1.2 0.6 2.7 2.4 2.7 1.5 0.8 0.5 0.7 2.9 2.6 0.7 0.5 1.0 0.6 0.4 3.0 0.7 0.6 4.2 0.4 0.8 3.4 0.6 0.6 1.5 3.1 0.7 0.5 16.2 2.8 0.9 1.2 3.3 0.9 0.6 0.5 5.0 0.5 1.3 1.7 1.2 2.7 2.4 0.7 1.7 1.4 0.7 1.7 1.2 0.8 1.3 1.0 1.1 3.3 0.5 1.5 1.0 1.2 1.6 1.0 0.8 1.7 1.9 1.7 0.3 0.5 1.1 2.5 2.2 0.6 1.2 0.7 3.4 1.1 0.7 1.9 0.6 1.2 4.6 1.2 0.3 0.5 1.9 0.6 0.4 0.9 0.5 2.5 0.8 1.8 0.1 2.1 1.8 1.0 0.9 0.5 1.4 0.3 1.9 0.5 1.8 2.5 2.9 2.1 1.4 1.1 0.0 0.3 0.3 0.3 0.4 1.4 0.5 0.4 0.9 1.0 0.3 1.3 1.3 0.0 0.6 0.1 0.5 0.9 0.4 2.5 2.8 2.5 4.4 2.4 2.7 2.9 2.6 3.0 3.1 2.8 5.0 4.1 0.0 3.7 50.6 2.0 10.8 6.4 18.8 4.0 13.3 4.5 5.8 2.2 2.8 9.9 5.5 4.2 3.1 3.2 0.5 9.8 3.5 342.0 7.5 6.4 4.6 3.0 4.8 41.6 5.1 1.8 6.2 1.5 3.7 3.8 7.0 3.6 2.3 3.6 6.7 52.0 1.5 18.3 2.1 19.4 295.3 5.0 2.8 10.6 16.9 2.4 10.8 3.1 32.6 50.7 1.5 1.6 9.1 1.4 4.3 1.3 9.5 12.9 9.7 0.0 6.3 7.9 35.3 17.2 1.7 11.1 4.5 3.4 6.2 0.9 3.8 CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 329.4;Hepatocytes: 149.5;Leydig cells: 91.0;Syncytiotrophoblasts: 481.9;Theca cells: 104.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 48.1;ASC diff: 57.9;ASC TERT1: 22.3;GAMG: 17.2;HAP1: 17.1;NTERA-2: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" 119.3 18.1 26.1 3.3 28.2 0.2 35.9 24.6 31.2 9.5 109.8 4.8 0.7 8.3 140.3 3.5 13.7 10.5 26.1 28.3 30.7 3.1 506.7 11.7 6.6 23.6 26.2 25.8 14.2 0.7 20.7 35.2 25.6 9.1 1.8 15.9 7.2 72.8 8.5 3.0 4.0 6.2 25.6 3.7 4.1 15.6 26.7 1.3 9.6 19.9 3.1 8.1 5.7 25.6 0.0 0.0 48.1 0.0 57.9 22.3 0.2 1.4 0.4 4.6 4.5 0.0 0.0 0.0 0.0 0.6 17.2 0.1 17.1 0.0 6.6 0.1 8.5 1.7 0.0 1.4 0.2 0.1 0.0 8.5 0.0 0.7 0.0 1.2 6.3 0.0 0.0 0.0 5.5 0.0 1.2 0.2 17.8 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 11.0 0.1 0.0 0.0 4.0 0.0 5.4 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 26.1 28.2 24.6 31.2 28.3 30.7 23.6 26.2 25.6 25.6 26.7 25.6 4.1 0.0 1.3 6.8 0.7 0.8 0.8 0.0 0.6 27.3 1.0 7.1 3.4 0.0 0.0 1.8 6.2 329.4 0.3 0.0 0.0 9.9 6.0 0.3 7.1 3.1 1.8 2.7 12.2 0.2 17.0 27.8 0.0 0.3 0.0 7.5 33.9 149.5 23.4 1.7 16.4 0.0 0.0 5.7 1.6 15.0 91.0 0.6 1.8 1.0 0.6 31.4 0.0 5.5 3.1 0.3 0.0 37.6 0.0 0.9 0.0 2.0 0.0 3.8 13.1 7.3 3.9 1.6 1.4 0.5 1.3 481.9 0.9 104.7 0.0 0.1 CEP126 KIAA1377 ENSG00000110318 "Centrosomal protein 126" Q9P2H0 11 101915010-102001062 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 143.7;Horizontal cells: 102.6;Respiratory ciliated cells: 138.5;Spermatocytes: 96.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 6.1;EFO-21: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038381, HPA038399" Uncertain Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "HPA038381: AB_10669780, HPA038399: AB_10670157" "unprognostic (7.61e-2)" "unprognostic (6.75e-2)" "unprognostic (9.07e-2)" "unprognostic (1.02e-2)" "unprognostic (9.31e-2)" "unprognostic (8.87e-2)" "unprognostic (1.55e-4)" "unprognostic (1.52e-2)" "unprognostic (5.77e-2)" "unprognostic (9.55e-2)" "unprognostic (7.72e-3)" "unprognostic (8.87e-2)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.30e-2)" "unprognostic (3.41e-1)" "unprognostic (9.61e-2)" "unprognostic (6.99e-3)" 5.4 4.9 8.2 0.8 9.9 0.9 3.8 9.5 12.3 7.1 16.2 4.2 0.6 4.3 2.6 2.0 9.2 1.9 4.2 9.1 7.1 2.2 0.4 4.4 1.4 9.2 8.9 7.8 2.0 1.4 18.1 0.9 7.4 3.5 1.9 11.1 2.4 3.0 1.0 3.9 2.2 2.1 9.2 1.8 1.9 16.8 8.9 0.8 4.1 1.5 0.8 3.7 5.1 9.0 0.5 1.0 0.6 0.8 6.1 3.3 0.3 0.9 1.1 0.5 0.4 0.3 1.8 0.6 5.7 1.1 2.6 0.5 0.7 1.4 0.4 1.8 0.9 0.1 2.6 0.7 0.7 0.1 0.1 1.0 3.0 0.7 1.5 3.3 1.5 0.8 0.1 0.2 1.3 0.6 0.6 0.1 0.5 0.7 0.9 0.1 0.6 0.0 1.3 0.8 1.7 2.7 0.8 1.2 0.1 1.2 2.2 0.2 1.0 1.7 0.9 0.5 1.4 1.3 0.7 0.1 1.9 0.1 0.5 0.3 0.1 0.3 0.4 0.0 0.3 0.5 0.3 0.4 0.1 0.6 0.4 0.4 0.4 0.9 0.0 1.2 0.1 0.1 8.2 9.9 9.5 12.3 9.1 7.1 9.2 8.9 7.4 9.2 8.9 9.0 6.7 9.6 6.7 0.0 7.2 0.0 5.1 0.0 5.2 29.7 6.4 11.9 6.9 8.6 23.5 18.4 45.9 1.3 20.2 0.5 3.9 2.4 21.7 143.7 45.1 4.0 66.7 2.5 0.0 0.4 0.6 33.4 8.2 3.6 0.0 19.0 3.3 0.0 0.4 102.6 0.0 9.4 0.0 0.3 0.0 12.0 53.7 2.8 0.0 0.0 0.7 25.8 20.6 0.0 0.0 1.1 1.7 51.1 3.5 3.0 0.5 6.0 138.5 53.7 6.6 18.3 11.3 96.3 26.2 1.4 0.0 0.1 6.3 39.3 1.7 2.0 CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Metabolic proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 551.5" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 626.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 280.5;ASC TERT1: 284.1;fHDF/TERT166: 271.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" 26.1 8.9 249.9 12.3 411.3 2.5 24.5 248.6 378.3 42.4 140.1 20.9 7.9 35.0 9.7 13.1 23.4 31.2 34.0 261.5 322.7 25.9 3.7 16.9 4.1 344.1 349.4 31.2 30.1 31.0 106.4 49.4 323.9 27.9 7.7 1.0 21.4 22.8 7.0 15.0 12.3 47.4 224.7 10.9 15.8 11.1 386.4 2.4 23.4 7.0 3.9 29.9 30.8 551.5 44.7 26.0 35.2 38.2 280.5 284.1 27.4 145.5 149.7 41.2 32.0 10.3 2.4 0.0 58.3 271.9 33.5 33.8 14.7 22.2 13.9 11.7 25.6 2.9 24.1 15.5 89.7 5.4 84.4 171.6 11.7 48.4 10.5 157.7 44.3 3.0 13.0 36.5 51.8 82.3 2.3 55.7 1.8 2.3 25.4 4.7 23.6 7.3 18.4 15.5 4.9 8.5 33.8 43.1 16.7 10.1 34.4 13.7 48.2 103.5 27.3 138.1 23.2 42.2 35.0 0.8 99.7 17.1 21.0 0.1 0.6 0.0 1.8 0.7 0.1 0.1 0.1 2.1 0.7 0.0 0.0 2.3 0.0 0.6 0.0 1.0 0.0 1.3 249.9 411.3 248.6 378.3 261.5 322.7 344.1 349.4 323.9 224.7 386.4 551.5 8.5 6.4 10.3 7.2 3.5 8.9 6.5 7.0 10.8 1.7 8.7 6.9 3.9 0.0 13.6 11.0 0.0 18.4 5.8 0.0 0.0 11.6 2.7 3.1 18.7 7.7 0.0 2.5 2.9 3.4 61.1 82.3 3.6 6.7 8.8 9.8 16.8 0.1 6.2 6.7 3.3 0.0 2.0 0.8 10.4 2.3 24.2 2.9 40.9 3.7 1.3 0.1 17.5 11.6 626.9 4.5 0.0 26.4 17.9 5.0 0.0 0.9 3.9 0.9 6.6 27.8 26.4 8.6 22.2 2.4 4.1 19.6 3.3 5.9 0.0 2.8 CERT1 "CERT, COL4A3BP, GPBP, STARD11" ENSG00000113163 "Ceramide transporter 1" Q9Y5P4 5 75356345-75512138 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 23.3;Cardiomyocytes: 37.1;Cytotrophoblasts: 17.7;dendritic cells: 20.2;Extravillous trophoblasts: 16.8;Hofbauer cells: 36.8;Plasma cells: 12.4;Syncytiotrophoblasts: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 132.3;WM-115: 118.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035645, HPA042608" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" Nucleoplasm "HPA035645: AB_10600700, HPA042608: AB_2678075" "unprognostic (2.45e-1)" "unprognostic (7.16e-2)" "unprognostic (6.56e-3)" "unprognostic (1.53e-2)" "unprognostic (2.44e-1)" "unprognostic (9.29e-2)" "unprognostic (4.06e-2)" "unprognostic (3.22e-1)" "unprognostic (2.51e-1)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "unprognostic (4.29e-2)" "prognostic favorable (1.24e-5)" "unprognostic (9.12e-2)" "unprognostic (2.29e-1)" "unprognostic (2.83e-1)" "unprognostic (2.91e-1)" 38.1 26.1 12.4 16.5 16.1 27.2 17.6 18.0 15.4 33.9 14.0 20.8 18.7 20.6 15.1 24.9 22.4 23.3 20.8 14.0 15.1 27.9 31.2 24.3 20.3 14.7 17.5 23.1 16.4 26.1 8.0 22.9 16.7 24.3 19.6 18.2 14.0 19.9 28.9 18.7 21.1 18.3 14.7 25.3 23.5 28.8 15.5 21.2 49.9 28.3 22.7 23.7 16.0 17.6 44.9 22.7 21.6 19.0 132.3 36.6 29.0 24.8 30.8 18.8 24.8 34.4 25.3 21.5 52.3 26.9 25.8 26.7 33.4 34.4 28.6 27.1 15.2 18.2 24.4 18.4 33.6 18.2 20.1 27.9 23.8 22.3 24.9 30.5 22.1 28.3 33.0 32.0 25.0 23.0 21.6 13.2 27.9 10.2 16.8 18.0 28.5 20.2 30.5 54.0 16.4 16.5 31.6 21.6 31.8 45.4 21.3 30.5 30.1 12.6 15.1 22.8 20.3 29.1 41.6 24.8 21.4 30.7 118.2 9.6 19.8 16.0 8.2 22.4 7.8 9.1 8.3 7.7 14.5 9.1 7.7 7.8 29.6 7.8 25.4 8.3 13.0 9.0 12.4 16.1 18.0 15.4 14.0 15.1 14.7 17.5 16.7 14.7 15.5 17.6 23.3 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 0.0 0.0 0.0 0.0 17.7 20.2 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 16.8 10.5 0.0 0.0 0.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 27.8 3.8 0.0 0.0 0.0 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 2613.2" "Cell type enhanced" "Detected in many" "Ductal cells: 873.6;Exocrine glandular cells: 197.3;Hepatocytes: 284.0;Pancreatic endocrine cells: 318.0;Proximal enterocytes: 139.7" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 15.0;ASC TERT1: 23.0;EFO-21: 25.1;fHDF/TERT166: 14.1;HSkMC: 19.1;U-87 MG: 10.1" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" NA NA 879000000 120000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 143.7 18.0 3.6 32.8 3.6 0.1 28.5 3.4 9.9 16.3 3.9 22.3 28.1 8.2 14.2 24.1 53.7 0.8 42.6 3.7 3.4 58.7 2613.2 39.2 4.2 4.1 3.7 9.9 51.8 0.2 17.7 5.0 3.8 60.3 14.5 1.4 43.3 0.0 3.0 7.7 73.1 48.3 3.4 12.9 54.5 2.1 3.7 1.9 15.5 0.7 6.7 17.8 9.2 3.6 0.5 1.9 0.1 0.0 15.0 23.0 0.1 0.0 0.2 1.1 0.0 0.1 8.6 0.1 25.1 14.1 0.6 6.0 0.0 1.8 1.2 1.0 0.3 0.7 0.4 0.5 0.0 1.0 0.4 19.1 0.4 0.6 0.5 1.3 0.2 0.1 0.3 0.7 0.1 0.2 0.1 0.3 0.4 0.0 0.4 0.3 0.3 1.3 1.7 0.5 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 3.4 1.2 0.4 0.4 0.7 2.1 1.0 10.1 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 3.6 3.4 9.9 3.7 3.4 4.1 3.7 3.8 3.4 3.7 3.6 1.0 0.0 16.9 0.0 2.6 0.8 0.9 64.8 11.4 0.3 4.9 0.9 0.4 44.3 127.3 5.5 0.0 0.1 0.0 3.7 3.9 873.6 0.0 1.9 0.4 3.9 2.4 16.0 0.2 197.3 0.2 34.6 20.9 1.2 0.0 0.0 11.7 284.0 1.0 0.0 0.2 8.5 18.3 19.7 1.0 0.0 2.8 1.1 0.0 5.6 18.1 0.4 0.0 0.0 0.0 318.0 10.6 0.0 0.1 8.6 139.7 17.1 75.4 0.7 0.0 1.0 12.6 0.1 0.1 3.9 1.8 1.6 1.6 0.0 12.4 4.5 CHIA "AMCase, CHIT2, TSA1902" ENSG00000134216 "Chitinase acidic" Q9BZP6 1 111290851-111320566 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Carbohydrate metabolism, Chitin degradation, Immunity, Inflammatory response, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "stomach 1: 327.5" "Cell type enriched" "Detected in some" 5 "Alveolar cells type 2: 34.6" "Group enriched" "Detected in some" 4 "lung cancer: 1.8;stomach cancer: 2.0;thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "ASC diff: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA059193 Approved "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 4: Stomach - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA059193: AB_2683942" "unprognostic (8.00e-2)" "unprognostic (7.08e-2)" "unprognostic (2.02e-2)" "unprognostic (4.99e-2)" "unprognostic (7.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" 0.3 0.2 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.6 0.5 1.6 0.3 0.0 0.1 0.1 0.1 0.1 0.2 10.6 0.3 0.2 0.1 0.1 0.2 2.0 1.9 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.1 0.0 327.5 0.5 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 34.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 CHP1 "CHP, p22, p24, Sid470p, SLC9A1BP" ENSG00000187446 "Calcineurin like EF-hand protein 1" Q99653 15 41230839-41281887 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Protein kinase inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 434.4;Distal tubular cells: 389.4;Hepatocytes: 353.6;Proximal enterocytes: 425.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006616 Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA006616: AB_1857461" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (2.84e-1)" "prognostic favorable (9.63e-4)" "unprognostic (7.29e-2)" "unprognostic (3.74e-1)" "prognostic favorable (4.07e-6)" "unprognostic (2.20e-1)" "unprognostic (7.46e-2)" "unprognostic (3.26e-2)" "unprognostic (1.26e-3)" "unprognostic (2.79e-1)" "prognostic favorable (2.79e-6)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-3)" "unprognostic (2.04e-1)" 66.9 55.3 22.1 28.0 24.4 58.4 32.8 26.0 26.5 34.0 24.7 113.8 85.4 21.8 34.1 74.5 20.8 48.1 53.2 30.3 32.9 76.1 185.1 52.7 18.6 32.9 31.0 19.1 42.2 54.1 21.6 26.3 35.8 34.3 81.9 20.5 49.9 27.5 81.0 45.5 70.0 27.6 26.9 20.2 112.7 10.7 33.3 20.1 49.8 86.5 41.1 44.8 41.3 28.4 72.4 72.7 28.3 109.0 120.4 113.8 41.0 56.2 69.1 44.8 48.0 66.6 140.4 12.6 59.8 77.7 47.7 89.0 56.0 83.9 51.5 44.8 20.0 50.8 58.1 103.6 93.5 66.5 73.7 116.7 98.8 51.9 53.3 68.0 82.1 37.9 81.2 79.5 52.5 43.5 27.7 72.5 29.0 118.4 35.9 35.9 46.2 34.0 92.5 144.1 17.4 44.3 96.4 178.2 48.7 49.9 101.0 66.3 108.3 47.5 50.3 76.9 36.7 45.0 131.6 59.4 84.9 42.2 44.1 255.5 227.6 274.8 49.5 204.4 51.5 40.2 46.2 50.0 152.1 33.0 29.1 41.4 173.3 56.5 207.4 95.1 60.7 116.5 22.1 24.4 26.0 26.5 30.3 32.9 32.9 31.0 35.8 26.9 33.3 28.4 28.3 44.8 117.3 20.9 26.8 72.3 62.4 48.1 20.5 11.0 101.6 39.2 80.5 243.1 50.7 103.0 10.4 33.3 38.3 434.4 389.4 96.7 52.5 68.0 48.8 39.5 55.6 58.5 24.8 150.6 62.4 38.2 112.7 114.4 37.4 18.9 78.1 353.6 68.5 11.8 21.0 136.2 34.6 170.1 134.8 122.6 29.5 77.1 129.9 19.7 113.4 32.7 36.0 9.5 23.6 173.9 206.4 29.3 24.0 80.1 425.0 231.1 33.7 10.3 26.3 46.6 41.4 13.7 19.3 50.6 108.5 66.9 32.9 65.7 161.4 130.8 CHPF2 "ChSy-3, CSGlcA-T, KIAA1402" ENSG00000033100 "Chondroitin polymerizing factor 2" Q9P2E5 7 151232489-151238827 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020992 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Cytosol" "HPA020992: AB_1847267" "unprognostic (8.31e-2)" "unprognostic (2.14e-3)" "unprognostic (1.02e-3)" "unprognostic (1.14e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "prognostic unfavorable (9.47e-4)" "unprognostic (4.07e-1)" "unprognostic (1.71e-1)" "unprognostic (4.54e-2)" "prognostic favorable (2.51e-4)" "unprognostic (1.04e-1)" "unprognostic (2.68e-3)" "unprognostic (2.24e-1)" "unprognostic (1.49e-1)" "unprognostic (3.22e-2)" "unprognostic (8.59e-3)" 13.7 31.7 9.5 17.4 9.3 23.1 13.6 3.8 12.9 14.6 13.5 17.4 13.0 19.5 10.3 14.0 14.6 15.1 19.8 9.6 11.6 14.9 20.4 17.6 16.6 11.1 8.7 14.0 26.2 13.2 43.7 16.1 10.0 19.1 9.0 2.9 22.2 12.9 8.1 14.7 18.9 14.9 5.4 28.9 20.1 9.6 10.5 10.9 17.6 5.0 10.7 16.7 13.6 6.7 27.9 22.3 14.7 43.1 50.0 49.2 22.2 57.3 88.4 30.5 37.1 14.9 46.1 8.4 98.7 91.6 41.5 34.3 6.5 40.8 13.1 32.1 20.3 8.9 25.4 21.0 46.7 18.2 70.9 75.8 22.7 28.9 10.3 63.1 48.6 13.8 8.6 23.7 49.2 45.7 17.0 70.6 19.7 11.6 25.6 15.8 8.7 28.1 29.6 21.7 15.9 28.1 30.7 29.8 15.2 11.0 11.6 29.4 66.9 33.6 5.6 45.2 49.3 43.3 6.8 12.3 122.3 23.9 46.6 0.9 4.4 6.2 4.0 3.6 3.7 1.9 2.1 3.6 4.7 2.0 1.4 1.6 7.2 2.0 3.9 6.9 2.4 3.3 9.5 9.3 3.8 12.9 9.6 11.6 11.1 8.7 10.0 5.4 10.5 6.7 8.3 9.6 11.8 2.3 11.2 4.6 6.6 15.1 6.2 8.8 10.5 5.6 1.9 10.0 11.7 11.0 4.2 11.5 23.4 21.3 1.9 12.4 0.6 6.5 11.0 8.9 8.4 8.6 6.1 16.8 16.3 13.3 18.8 9.0 6.3 14.6 12.5 9.6 12.6 25.2 5.0 12.0 14.2 10.9 6.8 1.0 17.1 11.1 7.2 3.7 11.0 5.3 11.3 5.5 1.8 17.7 17.4 15.1 26.5 11.5 8.5 3.5 8.8 7.4 19.7 7.8 14.6 5.0 3.1 6.6 4.4 10.3 13.0 15.8 9.8 10.5 CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Group enriched" "Detected in many" 4 "Astrocytes: 50.3;Fibroblasts: 83.8;Leydig cells: 41.0;Muller glia cells: 81.6" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "ASC diff: 537.8;ASC TERT1: 724.7;hTERT-RPE1: 341.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" 188.3 7.3 7.1 26.2 14.5 0.9 69.8 8.3 14.1 38.8 6.5 74.8 10.8 148.2 20.2 58.0 53.5 47.9 22.0 9.4 6.2 15.1 1.8 76.3 24.4 4.4 4.5 7.1 12.5 84.9 6.4 21.9 4.0 141.6 35.5 55.6 23.3 224.4 6.1 17.5 22.1 101.3 4.3 16.0 17.9 6.5 5.8 10.9 37.8 34.9 11.7 28.3 20.0 6.3 0.0 0.1 3.3 0.0 537.8 724.7 0.3 7.6 3.3 18.8 16.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.0 0.0 17.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 58.7 0.1 1.6 0.0 341.2 0.0 2.0 0.0 0.0 0.1 0.0 1.0 0.3 21.3 0.0 0.0 0.0 0.0 0.1 3.0 0.0 1.7 5.2 0.0 0.0 0.4 1.4 0.0 0.0 0.0 5.8 4.2 60.4 7.8 0.1 0.1 0.0 5.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.1 14.5 8.3 14.1 9.4 6.2 4.4 4.5 4.0 4.3 5.8 6.3 8.4 0.0 2.7 50.3 0.1 4.8 0.0 0.0 0.6 1.5 0.3 0.4 2.3 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 0.3 0.3 0.0 1.0 13.8 0.0 0.0 4.2 0.0 0.1 83.8 2.0 0.2 1.3 0.3 2.2 0.1 0.2 0.0 9.3 0.0 0.0 0.0 8.1 1.4 41.0 1.1 8.8 1.0 0.0 81.6 0.0 13.6 0.2 0.0 0.0 9.1 1.4 0.3 0.0 4.1 1.5 2.9 0.0 2.7 11.2 0.2 8.2 0.3 4.4 0.1 1.0 0.0 0.0 0.1 CHST2 C6ST ENSG00000175040 "Carbohydrate sulfotransferase 2" Q9Y4C5 3 143119771-143124014 "Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.4" "Cell type enhanced" "Detected in many" "Muller glia cells: 114.4;NK-cells: 233.8;Plasma cells: 79.3;Sertoli cells: 92.1;Theca cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.3;NK-cell: 4.9;non-classical monocyte: 11.4" "Group enriched" "Detected in many" 5 "monocytes: 11.4;NK-cells: 4.9" "Cell line enhanced" "Detected in many" "ASC diff: 57.7;ASC TERT1: 58.8;HEL: 48.2;HHSteC: 118.4;HMC-1: 55.4;HSkMC: 62.3;U-266/70: 52.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013620 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA013620: AB_2668861" "unprognostic (1.55e-2)" "unprognostic (2.20e-1)" "unprognostic (7.64e-3)" "unprognostic (2.75e-1)" "unprognostic (8.97e-3)" "unprognostic (2.83e-1)" "unprognostic (2.70e-2)" "unprognostic (2.06e-1)" "unprognostic (2.76e-1)" "unprognostic (4.11e-2)" "unprognostic (8.96e-3)" "unprognostic (9.15e-2)" "unprognostic (1.31e-2)" "unprognostic (7.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.58e-3)" "unprognostic (1.34e-1)" 7.7 2.7 17.8 8.1 13.7 16.8 6.3 16.7 14.6 5.7 6.0 3.0 2.1 8.4 1.4 1.1 2.1 1.7 5.6 9.7 13.4 8.4 1.3 7.5 7.7 31.0 18.4 4.9 1.3 0.9 6.9 10.3 28.1 7.4 1.1 11.0 2.7 9.9 1.6 4.4 7.5 3.7 21.4 18.2 3.4 1.7 28.7 14.5 6.7 0.8 5.4 7.1 7.6 48.4 0.0 0.3 3.1 2.6 57.7 58.8 0.2 3.3 9.5 2.3 2.1 0.0 0.0 0.6 2.0 2.3 3.1 0.1 2.3 8.2 1.2 0.8 1.5 48.2 0.1 0.0 118.4 1.2 55.4 62.3 9.7 3.1 10.1 3.6 3.6 7.2 5.5 2.9 15.4 0.0 9.1 12.2 16.5 0.0 8.0 0.5 1.0 0.1 1.7 2.2 3.7 0.0 0.7 0.0 5.6 2.9 0.0 1.9 12.3 7.0 4.1 9.5 13.9 52.4 0.8 3.3 13.8 9.3 37.4 0.7 0.5 0.7 0.3 4.3 0.0 1.1 0.1 0.2 1.6 0.8 0.6 0.5 0.3 4.9 11.4 0.1 0.5 0.9 17.8 13.7 16.7 14.6 9.7 13.4 31.0 18.4 28.1 21.4 28.7 48.4 11.3 0.0 0.0 3.6 17.7 2.4 7.3 2.5 0.0 25.0 2.8 2.7 1.4 0.0 1.8 3.7 2.1 0.6 41.9 0.0 0.0 0.4 0.2 5.7 29.8 9.4 0.0 39.1 6.8 0.2 0.6 14.4 2.0 6.5 11.4 12.5 3.6 0.4 2.8 1.7 8.1 0.0 0.0 10.3 32.2 1.3 12.8 20.2 17.8 1.0 13.6 114.4 233.8 2.5 6.1 5.9 0.0 2.2 79.3 13.1 0.0 0.0 0.1 23.8 92.1 0.8 20.2 0.0 2.2 0.1 0.6 1.0 9.8 58.1 1.3 14.8 CHSY3 "CHSY-2, CSS3" ENSG00000198108 "Chondroitin sulfate synthase 3" Q70JA7 5 129904465-130186634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 509.1;Inhibitory neurons: 349.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 2.0;basal ganglia: 2.6;cerebral cortex: 2.9;hippocampal formation: 2.5;white matter: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.1;ASC TERT1: 11.5;HSkMC: 7.6;TIME: 7.4;U-138 MG: 14.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044612 Uncertain "Intracellular and membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA044612: AB_10795883" "unprognostic (3.43e-2)" "unprognostic (6.28e-3)" "unprognostic (1.76e-2)" "unprognostic (5.83e-2)" "unprognostic (5.88e-2)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (9.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.08e-6)" "unprognostic (5.22e-3)" "unprognostic (9.93e-2)" "unprognostic (4.61e-3)" "unprognostic (1.74e-2)" 6.0 0.5 2.0 1.0 2.6 0.0 2.8 0.0 2.9 4.5 0.0 0.7 0.5 1.5 0.1 0.6 1.1 2.8 1.3 2.5 0.2 0.2 1.7 1.8 0.5 0.0 0.4 0.3 0.3 0.4 0.3 2.2 0.0 0.5 0.5 1.0 0.5 0.6 1.0 1.3 0.5 2.0 0.2 0.7 0.5 0.7 0.4 0.2 1.2 0.5 0.4 1.7 1.9 1.1 0.0 0.1 1.2 0.0 13.1 11.5 1.0 3.0 0.1 0.4 0.4 0.0 0.1 0.0 0.3 4.6 0.0 0.0 0.0 0.1 0.0 0.0 1.6 1.9 5.6 0.5 1.2 0.0 0.0 7.6 0.0 0.1 1.2 0.6 3.2 0.0 0.0 1.9 5.2 0.0 0.0 0.0 0.7 0.0 1.2 0.4 5.7 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.3 1.1 0.2 0.5 7.4 14.2 3.0 0.2 2.0 0.0 0.0 0.0 0.3 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.6 0.0 2.9 2.5 0.2 0.0 0.4 0.0 0.2 0.4 1.1 2.0 9.6 1.1 20.2 0.0 0.5 0.0 0.0 1.2 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.9 0.5 14.8 2.4 0.0 0.0 509.1 0.0 0.1 2.9 0.0 0.3 0.0 4.1 3.6 1.8 1.9 0.0 349.5 0.0 0.0 1.3 0.7 0.1 1.2 0.1 3.6 87.1 0.0 1.3 0.0 76.9 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.1 6.6 0.9 6.3 1.6 0.7 0.3 0.3 0.4 0.2 0.6 0.0 0.1 CIDEC "CIDE-3, FLJ20871, Fsp27" ENSG00000187288 "Cell death inducing DFFA like effector c" Q96AQ7 3 9866711-9880255 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 740.3;breast: 492.9" "Cell type enriched" "Detected in some" 7 "Proximal enterocytes: 219.4" "Group enriched" "Detected in many" 5 "breast cancer: 4.5;colorectal cancer: 1.4;liver cancer: 2.4;pancreatic cancer: 4.6;stomach cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC diff: 1683.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018837, HPA020553" Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "HPA018837: AB_1846767, HPA020553: AB_1846769" "unprognostic (1.83e-2)" "unprognostic (3.08e-2)" "unprognostic (2.32e-1)" "unprognostic (1.83e-1)" "unprognostic (1.19e-1)" "unprognostic (7.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-5)" "unprognostic (9.03e-2)" "unprognostic (1.81e-1)" "unprognostic (5.48e-3)" "unprognostic (8.14e-2)" "unprognostic (5.37e-5)" "unprognostic (9.47e-3)" "unprognostic (2.02e-1)" "unprognostic (7.46e-3)" "unprognostic (2.94e-2)" 740.3 5.6 0.1 1.1 0.2 0.0 492.9 0.0 0.4 1.2 0.0 15.9 68.9 4.6 0.3 0.7 2.2 5.0 9.5 0.1 0.1 2.1 10.0 0.2 1.2 0.1 0.2 0.4 7.4 0.1 0.2 0.0 0.2 2.3 3.9 0.0 16.2 3.7 6.1 18.1 89.8 1.6 0.1 0.2 7.4 0.9 0.2 1.5 3.9 11.6 0.0 13.3 4.8 0.2 0.0 0.2 0.0 0.0 1683.2 376.0 1.2 0.1 0.0 0.0 0.0 7.5 9.1 0.0 0.2 0.6 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 19.1 2.8 0.0 0.0 228.9 0.4 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.3 0.0 0.6 1.6 0.0 0.0 1.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 2.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 2.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 30.0 1.9 0.0 0.5 0.2 0.1 0.1 3.5 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.1 8.4 0.0 0.0 0.4 1.0 2.5 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 14.5 0.4 0.0 0.4 219.4 1.1 0.0 0.0 0.0 0.5 0.6 0.6 0.4 0.0 0.0 0.0 0.2 0.1 3.8 0.3 CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 138.1;Leydig cells: 231.5;Peritubular cells: 57.6;Theca cells: 83.5" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.2;ASC TERT1: 2.5;EFO-21: 1.1;HSkMC: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" 49.8 0.8 0.2 9.5 0.2 0.1 21.9 0.3 0.3 44.9 0.1 20.3 2.3 13.8 3.6 11.0 15.8 36.8 27.4 0.2 0.2 1.0 1.6 2.9 1.6 0.2 0.2 7.5 3.0 0.3 0.7 2.5 0.2 3.1 6.9 0.5 9.4 4.8 15.5 14.0 22.6 51.0 0.2 0.6 8.3 12.1 0.2 1.8 2.4 32.9 0.8 26.9 28.1 0.2 0.0 0.0 0.0 0.0 4.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 8.1 0.0 0.0 0.0 0.0 5.2 0.1 0.2 0.0 0.9 0.4 0.5 2.1 0.0 0.4 1.8 0.0 0.0 0.2 0.1 0.0 0.1 1.7 1.2 42.9 1.5 0.0 0.0 0.3 0.0 0.0 138.1 4.1 1.7 0.0 0.1 2.2 0.1 0.1 0.0 0.6 0.1 2.0 0.0 11.9 7.1 231.5 1.7 1.8 1.9 0.0 0.2 0.0 1.0 0.3 0.0 0.0 57.6 0.3 0.1 0.0 0.0 0.0 0.1 0.0 14.7 6.6 0.6 0.3 0.1 6.1 0.0 1.6 83.5 0.2 0.0 CILP2 MGC45771 ENSG00000160161 "Cartilage intermediate layer protein 2" Q8IUL8 19 19538248-19546659 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.5" "Cell type enhanced" "Detected in some" "Early spermatids: 26.2;Late spermatids: 21.8;Sertoli cells: 6.6;Spermatocytes: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.6;HEK 293: 2.8;NB-4: 2.2;THP-1: 2.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "medulla oblongata: 2.7;spinal cord: 7.3" HPA041847 Uncertain "Secreted to extracellular matrix" NA NA 22000000 "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA041847: AB_10795599" "unprognostic (6.51e-2)" "unprognostic (2.54e-2)" "unprognostic (5.42e-4)" "prognostic unfavorable (3.22e-6)" "unprognostic (4.81e-2)" "unprognostic (1.73e-1)" "unprognostic (4.31e-2)" "unprognostic (4.13e-3)" "unprognostic (4.48e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (5.09e-2)" "unprognostic (1.41e-2)" "unprognostic (0.00e+0)" "unprognostic (1.59e-2)" "unprognostic (3.19e-2)" "unprognostic (3.12e-3)" "unprognostic (1.36e-2)" 0.8 0.0 0.4 0.2 0.7 1.0 0.3 0.0 0.4 0.3 0.0 0.1 0.0 0.2 0.1 0.0 0.4 1.5 0.4 0.4 1.2 0.3 0.2 0.4 0.3 0.2 0.2 1.6 0.0 0.1 0.3 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.3 0.3 0.1 0.1 0.0 0.2 0.0 5.5 0.9 0.0 1.0 0.0 0.1 0.3 0.2 0.1 0.0 0.1 0.1 0.1 4.6 0.1 0.6 0.6 0.0 0.3 0.0 1.3 0.5 0.0 1.2 0.2 0.0 0.5 0.1 0.0 0.0 0.3 2.8 0.0 0.1 0.1 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 2.2 1.7 1.5 0.9 0.3 0.0 0.0 0.0 0.0 0.1 1.2 0.3 1.5 0.1 0.2 0.3 2.8 0.0 0.0 0.5 0.2 0.1 0.4 1.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.4 0.4 1.2 0.2 0.2 0.2 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.0 0.5 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 26.2 0.3 0.3 0.1 0.0 0.0 0.2 0.0 0.2 1.5 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.3 21.8 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 1.4 0.0 0.1 0.0 0.0 6.6 0.4 0.3 27.8 4.0 0.7 0.6 0.0 0.2 0.1 0.0 0.5 CLCN1 "ClC-1, CLC1" ENSG00000188037 "Chloride voltage-gated channel 1" P35523 7 143316111-143352083 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 65.9" "Cell type enriched" "Detected in some" 4 "Late spermatids: 149.6" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "HSkMC: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (5.16e-2)" "unprognostic (4.99e-2)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (9.53e-2)" "unprognostic (8.53e-2)" "unprognostic (1.42e-1)" "unprognostic (2.56e-4)" "unprognostic (8.71e-3)" "unprognostic (2.35e-1)" "unprognostic (2.90e-3)" "unprognostic (3.12e-1)" "unprognostic (2.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.47e-1)" "unprognostic (3.55e-3)" "unprognostic (3.57e-2)" 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 65.9 0.0 1.0 0.0 0.0 0.1 0.2 1.0 0.0 0.2 0.0 15.9 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.1 0.8 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 32.9 0.0 0.2 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.1 0.0 0.0 0.8 149.6 0.0 0.7 0.0 1.0 0.6 0.0 0.0 0.0 0.7 5.7 15.0 0.0 0.0 0.2 0.4 0.1 0.3 0.0 0.0 1.4 0.3 0.1 2.2 0.7 0.1 0.0 0.1 0.1 0.2 2.1 CLEC3B "TN, TNA" ENSG00000163815 "C-type lectin domain family 3 member B" P05452 3 45001548-45036071 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 420.3" "Cell type enhanced" "Detected in some" "Adipocytes: 76.3;Endothelial cells: 27.9;Fibroblasts: 126.4;Hepatic stellate cells: 57.5;Leydig cells: 30.1;Microglial cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 297.9;ASC TERT1: 591.9;U-2197: 120.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002582, HPA034794" Approved "Secreted to blood" NA NA 6540000000 25000000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB002582: AB_564027, HPA034794: AB_2674332" "unprognostic (2.04e-1)" "unprognostic (1.80e-3)" "unprognostic (2.58e-1)" "unprognostic (4.57e-2)" "unprognostic (7.75e-2)" "prognostic favorable (1.53e-4)" "prognostic favorable (9.99e-9)" "unprognostic (1.75e-2)" "unprognostic (2.25e-1)" "unprognostic (4.02e-1)" "prognostic favorable (5.68e-4)" "unprognostic (9.33e-2)" "unprognostic (2.39e-2)" "unprognostic (7.46e-2)" "unprognostic (1.39e-1)" "unprognostic (5.54e-2)" "unprognostic (4.21e-2)" 420.3 51.0 44.4 9.3 46.4 1.7 214.8 45.5 66.6 89.4 50.9 83.9 31.6 60.4 17.1 49.9 41.1 35.6 259.9 43.0 42.9 131.4 29.0 201.2 33.1 51.3 56.1 26.0 14.6 14.3 27.7 142.8 48.0 33.5 37.4 0.7 49.8 19.1 74.8 149.7 78.2 25.5 44.8 264.5 43.5 113.2 50.7 10.1 88.4 68.0 8.2 100.9 74.9 43.0 0.0 0.0 0.1 0.2 297.9 591.9 0.0 40.1 62.9 1.2 6.2 0.0 0.0 0.1 0.1 3.1 0.0 0.1 0.0 0.1 0.1 0.3 0.9 0.6 0.1 0.1 0.5 0.1 0.7 47.5 0.1 0.3 0.1 0.4 0.5 0.3 0.0 1.7 0.5 0.2 0.0 2.2 0.0 0.0 0.6 0.0 0.1 2.2 0.0 0.0 0.3 1.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 4.5 0.2 120.6 0.1 1.0 1.2 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.4 46.4 45.5 66.6 43.0 42.9 51.3 56.1 48.0 44.8 50.7 43.0 76.3 0.0 0.0 1.6 0.3 3.4 0.0 0.0 1.8 0.0 0.7 0.3 0.8 1.5 0.0 0.0 0.0 0.0 0.5 0.0 3.9 0.0 4.0 0.3 16.9 27.9 0.0 2.7 0.8 0.2 0.0 126.4 3.1 0.3 0.0 0.0 57.5 0.3 0.9 0.0 0.6 0.0 0.0 1.2 9.5 19.5 30.1 2.2 3.6 69.3 0.7 0.4 0.0 1.5 0.7 0.1 0.0 6.4 0.5 0.0 0.0 0.0 0.0 0.3 0.0 1.0 12.3 0.0 0.0 0.7 3.8 0.1 0.7 0.4 0.0 0.0 CLEC4A "CD367, CLECSF6, DCIR, DDB27" ENSG00000111729 "C-type lectin domain family 4 member A" Q9UMR7 12 8123617-8138607 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 21.6;lymphoid tissue: 26.9" "Group enriched" "Detected in many" 4 "Kupffer cells: 79.9;Langerhans cells: 119.3;Macrophages: 88.5;monocytes: 98.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 226.8;classical monocyte: 331.7;intermediate monocyte: 198.1;myeloid DC: 327.4;neutrophil: 298.3;non-classical monocyte: 130.0" "Group enriched" "Detected in all" 13 "dendritic cells: 327.4;granulocytes: 298.3;monocytes: 331.7" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA007842 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA007842: AB_1078534" "unprognostic (9.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.41e-2)" "unprognostic (3.13e-2)" "unprognostic (2.69e-1)" "unprognostic (9.34e-2)" "unprognostic (5.49e-2)" "unprognostic (8.22e-2)" "unprognostic (1.62e-1)" "unprognostic (7.84e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.42e-3)" "unprognostic (1.42e-1)" "unprognostic (1.35e-2)" "unprognostic (3.05e-1)" "unprognostic (9.79e-2)" 4.1 2.4 3.0 26.9 3.0 21.6 4.6 3.1 5.9 3.2 2.9 4.6 5.1 3.9 4.3 2.6 2.6 7.4 1.9 3.0 3.0 1.7 4.2 11.1 9.4 4.0 3.1 4.3 1.8 1.0 2.0 4.9 3.1 2.3 6.0 3.5 2.8 3.0 1.6 5.4 4.7 4.6 3.1 15.4 2.4 2.4 2.6 6.2 1.7 2.6 8.9 7.7 1.8 3.3 0.2 0.0 0.3 0.9 1.7 4.2 0.5 1.2 0.5 0.9 1.3 1.6 0.7 0.7 0.1 0.6 0.3 0.2 0.9 0.2 0.6 1.2 1.2 0.7 0.7 0.4 2.1 2.3 2.9 2.1 0.9 0.4 1.2 2.7 0.2 1.6 0.4 0.6 1.2 0.6 0.6 1.7 0.6 0.6 0.4 0.4 0.7 1.1 0.6 1.1 0.2 0.4 0.2 0.8 0.0 1.4 0.1 0.1 0.2 1.6 1.0 0.6 0.8 0.7 0.1 0.9 0.2 0.8 0.0 226.8 331.7 1.1 0.5 198.1 0.6 14.1 0.9 1.3 327.4 25.0 0.6 0.6 298.3 3.3 130.0 44.4 0.6 168.9 3.0 3.0 3.1 5.9 3.0 3.0 4.0 3.1 3.1 3.1 2.6 3.3 1.1 0.0 4.6 3.9 8.6 4.2 0.8 0.6 0.0 0.6 0.7 2.0 0.8 0.0 2.0 0.0 4.2 0.3 8.9 0.4 1.9 0.1 5.5 0.2 0.6 1.5 1.8 2.7 2.2 0.5 0.2 1.4 0.5 0.3 2.5 1.5 0.7 1.3 23.8 0.0 2.4 0.3 0.0 79.9 119.3 1.5 2.5 88.5 7.2 3.7 98.8 1.0 6.2 4.5 2.9 0.6 1.2 1.5 0.7 0.8 0.0 0.3 2.3 1.1 0.0 1.1 1.1 0.6 0.4 0.3 3.3 0.3 2.1 0.7 0.2 0.9 CLIP3 "CLIPR-59, RSNL1" ENSG00000105270 "CAP-Gly domain containing linker protein 3" Q96DZ5 19 36014660-36033343 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 158.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.9;Excitatory neurons: 24.8;Granulosa cells: 25.7;Horizontal cells: 42.1;Inhibitory neurons: 30.7;Muller glia cells: 26.9;Peritubular cells: 24.5" "Cancer enhanced" "Detected in all" "glioma: 65.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 83.3;fHDF/TERT166: 61.5;HSkMC: 93.1;hTERT-RPE1: 80.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079430 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA079430: " "unprognostic (1.91e-2)" "unprognostic (8.70e-2)" "unprognostic (1.16e-2)" "unprognostic (5.01e-2)" "unprognostic (1.19e-1)" "unprognostic (1.38e-1)" "unprognostic (3.60e-2)" "unprognostic (2.92e-2)" "unprognostic (2.55e-2)" "unprognostic (3.26e-2)" "prognostic favorable (2.80e-4)" "unprognostic (9.44e-2)" "prognostic unfavorable (1.56e-10)" "unprognostic (6.31e-3)" "unprognostic (1.52e-1)" "unprognostic (9.63e-2)" "unprognostic (1.09e-2)" 16.4 13.5 109.8 9.7 117.0 0.5 14.0 92.0 142.5 50.9 0.3 75.3 6.5 66.2 12.7 16.3 35.7 23.5 12.7 122.5 121.5 11.5 2.9 10.0 7.0 105.2 158.4 48.6 3.6 2.6 46.9 9.3 140.0 29.2 8.6 54.9 6.3 33.4 3.4 7.8 21.4 37.9 60.3 9.9 25.7 12.0 92.6 9.4 5.5 3.5 6.2 68.2 32.4 106.2 1.3 3.8 33.0 1.4 53.8 83.3 1.1 19.1 45.9 15.6 23.4 4.0 1.3 1.8 7.6 61.5 1.3 1.6 0.6 0.2 11.1 2.4 1.3 1.0 4.1 0.8 54.1 1.0 1.0 93.1 0.9 13.4 0.3 80.8 17.7 13.0 1.9 3.5 35.2 2.9 18.6 1.3 4.0 1.3 0.9 2.4 0.6 1.1 0.5 1.2 32.2 37.6 2.2 0.8 1.0 13.5 1.2 0.4 4.9 26.8 21.9 1.3 1.2 2.8 2.5 1.4 41.1 1.8 10.2 0.0 0.1 0.3 0.2 0.2 0.0 0.2 0.3 0.1 0.0 0.1 0.3 0.2 0.1 0.4 0.0 0.1 0.2 0.1 109.8 117.0 92.0 142.5 122.5 121.5 105.2 158.4 140.0 60.3 92.6 106.2 1.1 0.0 0.0 11.4 0.1 0.6 0.6 0.5 0.6 30.9 0.4 4.3 4.3 0.0 0.1 1.8 2.1 0.6 0.0 0.3 0.0 0.1 11.3 0.7 15.3 3.6 2.4 0.0 24.8 0.2 0.5 16.1 1.1 0.7 0.0 25.7 5.0 0.2 0.8 42.1 30.7 0.9 0.0 0.3 2.3 19.2 22.1 0.5 3.6 10.3 0.0 26.9 0.0 14.6 15.3 0.3 0.0 24.5 0.2 0.4 0.3 0.3 0.7 13.7 6.6 8.7 12.8 2.3 3.5 0.5 1.3 1.2 0.6 2.9 0.2 0.1 CLN5 ENSG00000102805 "CLN5 intracellular trafficking protein" O75503 13 76990660-77019143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 128.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041788 Approved "Intracellular and membrane" NA NA 470000 "Cluster 2: Granulocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA041788: AB_10962726" "unprognostic (1.19e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.02e-1)" "unprognostic (9.82e-2)" "unprognostic (2.07e-3)" "unprognostic (3.41e-1)" "unprognostic (7.80e-2)" "unprognostic (2.29e-1)" "unprognostic (2.90e-1)" "unprognostic (6.98e-2)" "unprognostic (2.65e-1)" "prognostic favorable (1.52e-9)" "unprognostic (2.35e-1)" "unprognostic (7.04e-2)" "unprognostic (5.64e-2)" "unprognostic (8.15e-2)" 20.9 19.8 13.9 14.4 12.8 13.3 21.8 27.0 18.9 25.1 17.0 16.1 11.3 19.1 41.9 10.9 24.5 25.2 14.2 13.5 10.5 50.5 35.5 20.5 19.8 12.5 11.6 26.6 16.8 45.6 14.4 23.3 12.2 22.3 16.5 24.1 21.4 22.7 8.4 14.6 13.6 15.9 7.0 16.7 18.8 16.1 13.0 18.3 72.9 10.7 18.5 18.8 12.0 19.0 25.0 11.7 16.4 13.7 74.4 48.5 21.1 23.7 43.3 18.4 31.9 12.3 23.2 9.7 17.3 33.5 21.0 25.0 11.5 25.5 20.0 18.4 21.5 13.9 13.1 12.2 33.8 19.5 20.4 43.6 28.4 8.9 18.7 37.1 33.0 13.5 9.4 17.2 43.2 7.7 11.6 12.5 10.7 48.6 10.4 9.5 14.4 9.0 42.6 13.8 7.3 11.3 14.1 17.4 26.3 21.3 19.0 26.0 31.2 13.2 10.4 15.4 14.2 21.7 30.0 12.2 35.4 13.5 29.2 58.4 15.6 39.4 3.5 22.4 3.1 13.2 17.0 6.0 10.8 14.5 21.5 13.3 11.4 1.0 27.7 11.0 25.6 14.1 13.9 12.8 27.0 18.9 13.5 10.5 12.5 11.6 12.2 7.0 13.0 19.0 30.5 16.0 32.4 16.6 29.2 11.5 32.5 75.1 17.1 19.8 22.3 20.2 8.7 25.8 59.2 68.0 10.4 53.2 15.2 24.0 9.8 39.3 1.6 26.6 25.0 24.1 13.8 7.8 9.7 38.4 128.5 36.9 13.3 24.8 22.2 23.5 25.7 33.0 48.1 6.7 12.6 13.6 97.6 22.4 16.7 4.5 49.7 22.7 24.9 11.2 31.5 50.4 5.2 15.6 21.5 25.0 14.4 47.4 18.8 23.1 23.9 44.1 48.2 25.4 19.7 24.4 27.2 25.8 34.7 14.6 11.5 46.4 15.2 34.0 11.4 21.8 CMKLR1 RVER1 ENSG00000174600 "Chemerin chemokine-like receptor 1" Q99788 12 108288044-108339317 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.3" "Cell type enhanced" "Detected in some" "dendritic cells: 17.3;Hofbauer cells: 32.4;Kupffer cells: 69.6;Macrophages: 27.1;Microglial cells: 39.4;NK-cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 14.5;plasmacytoid DC: 18.1" "Group enriched" "Detected in many" 22 "dendritic cells: 18.1;monocytes: 14.5;T-cells: 7.0" "Cell line enhanced" "Detected in some" "ASC diff: 11.9;ASC TERT1: 45.3;BJ hTERT+: 34.9;hTERT-RPE1: 13.6;LHCN-M2: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047865 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA047865: AB_2680191" "unprognostic (1.78e-1)" "unprognostic (2.61e-2)" "unprognostic (8.83e-3)" "unprognostic (7.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-3)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (1.06e-1)" "unprognostic (8.72e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-2)" "unprognostic (5.19e-2)" "unprognostic (1.14e-1)" 10.4 5.9 3.3 11.7 3.0 0.9 4.9 2.5 3.2 4.7 4.2 7.5 4.5 8.3 1.6 3.1 4.4 5.5 6.4 2.6 4.9 3.3 6.9 12.8 17.6 5.9 4.7 1.9 3.2 1.7 3.4 22.2 5.3 3.8 8.9 0.3 4.7 4.5 2.4 4.2 5.1 14.7 4.0 34.3 2.8 2.6 5.9 4.2 8.7 5.1 8.1 8.1 2.5 7.5 0.0 0.0 0.1 0.0 11.9 45.3 0.2 0.0 34.9 0.1 0.0 0.0 0.0 0.2 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.2 13.6 0.7 0.0 0.0 0.0 10.6 0.0 0.0 1.0 0.1 0.0 0.0 0.0 1.9 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 4.1 0.0 7.0 14.5 0.0 0.0 1.1 5.1 1.1 0.0 0.4 3.5 0.3 0.6 2.8 18.1 0.3 5.1 3.3 3.0 2.5 3.2 2.6 4.9 5.9 4.7 5.3 4.0 5.9 7.5 1.9 0.0 0.0 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.1 0.3 2.2 1.5 0.6 0.0 0.0 0.4 17.3 0.0 0.0 0.0 0.1 0.0 0.7 5.8 0.0 2.7 0.5 0.0 0.5 7.8 0.0 0.0 0.0 0.0 11.4 0.6 32.4 0.0 0.4 0.0 0.0 69.6 2.5 0.3 0.3 27.1 3.6 39.4 7.6 0.0 30.9 1.0 0.0 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.7 0.1 6.6 4.1 5.1 0.0 0.0 0.1 0.6 0.5 2.2 0.5 0.0 0.0 CNPY4 "MGC40499, PRAT4B" ENSG00000166997 "Canopy FGF signaling regulator 4" Q8N129 7 100119634-100125508 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Leydig cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014166, HPA025240" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA014166: AB_1853895, HPA025240: AB_2082630" "unprognostic (9.64e-2)" "unprognostic (1.59e-2)" "unprognostic (4.09e-3)" "unprognostic (8.44e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.71e-1)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (6.16e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (6.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (1.35e-2)" 13.7 16.8 13.3 9.6 13.9 6.1 11.0 14.3 14.9 24.6 14.7 14.1 6.4 21.2 14.8 5.7 15.4 16.7 13.1 13.1 13.7 10.4 6.6 9.2 10.8 14.2 13.8 24.5 4.5 12.8 16.6 21.3 14.1 10.8 9.9 17.2 5.7 15.9 5.1 8.3 9.7 21.4 13.8 13.6 7.8 6.8 13.6 14.3 10.4 7.1 9.8 12.4 14.8 14.3 7.9 13.5 33.2 59.6 76.0 36.5 16.6 29.0 31.2 14.9 27.8 7.5 7.0 17.2 32.9 52.5 10.9 7.9 13.0 14.2 15.6 16.2 13.4 7.1 23.3 10.4 21.5 12.1 12.8 33.4 3.8 13.7 6.2 32.7 52.4 8.2 6.0 11.1 21.5 22.9 25.8 15.9 17.1 5.0 19.2 7.5 24.9 9.2 15.4 2.0 8.3 16.9 27.8 22.4 15.4 21.4 11.3 6.7 42.9 47.5 28.5 20.2 13.3 9.4 16.3 15.3 27.8 18.4 19.7 11.8 5.1 8.6 15.1 11.2 19.8 3.9 15.6 19.0 7.2 2.9 12.7 19.0 2.3 12.3 13.9 4.6 13.8 6.7 13.3 13.9 14.3 14.9 13.1 13.7 14.2 13.8 14.1 13.8 13.6 14.3 15.2 6.4 2.6 4.2 3.4 3.6 2.3 7.9 2.8 6.9 3.4 6.2 3.4 5.7 4.0 12.9 2.1 35.3 5.2 3.7 1.9 6.4 0.5 5.1 20.2 15.0 2.4 11.8 3.4 2.5 10.3 28.4 1.1 4.2 9.5 16.1 18.2 1.3 14.0 8.4 4.0 1.9 4.1 2.5 2.4 2.2 35.1 4.7 16.0 2.8 5.1 26.6 8.2 2.0 2.8 2.4 2.8 31.6 1.9 0.5 2.8 3.3 4.4 15.8 13.1 12.7 15.5 1.1 4.5 2.1 3.8 18.3 8.6 30.5 2.3 1.0 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.0;brain: 25.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 44.6;Inhibitory neurons: 200.3;Sertoli cells: 98.6" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 81.4;HSkMC: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 23.0 5.4 10.4 3.5 25.1 0.7 16.9 7.5 22.8 5.7 0.0 12.3 1.1 6.9 2.6 2.4 11.2 2.0 1.0 19.5 11.8 0.9 0.1 4.0 4.4 9.9 1.1 3.8 1.5 0.5 20.7 3.1 0.5 2.9 2.9 1.5 2.6 2.1 2.4 3.8 10.5 3.6 0.0 1.7 4.3 1.2 18.0 1.3 5.1 1.2 6.6 4.1 5.1 3.0 0.0 0.1 3.8 0.0 81.4 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.2 1.9 2.9 0.0 5.3 0.0 0.0 53.8 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.5 0.0 6.8 0.0 1.7 0.1 0.0 0.0 0.0 0.3 0.0 1.4 4.9 0.0 0.0 0.1 0.0 0.0 1.6 7.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 25.1 7.5 22.8 19.5 11.8 9.9 1.1 0.5 0.0 18.0 3.0 3.4 0.0 10.4 3.6 7.1 0.6 0.5 0.0 0.0 1.7 0.1 0.4 0.9 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.4 3.8 0.0 0.0 44.6 0.0 0.0 0.9 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 200.3 0.0 0.0 0.3 0.8 0.0 1.5 0.2 0.0 5.6 0.0 0.0 0.0 9.0 3.2 0.0 0.1 0.4 4.2 0.0 0.0 0.0 0.0 0.2 98.6 6.4 12.4 0.0 0.5 0.2 0.1 0.1 0.5 0.0 0.0 0.8 CNTD1 "CNTD, FLJ40137" ENSG00000176563 "Cyclin N-terminal domain containing 1" Q8N815 17 42798800-42811587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "testis: 42.4" "Group enriched" "Detected in many" 5 "Early spermatids: 70.5;Late spermatids: 124.8;Respiratory ciliated cells: 47.0;Spermatocytes: 150.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.9;ASC diff: 1.6;SiHa: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA072363 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Vesicles "HPA072363: " "unprognostic (5.92e-2)" "unprognostic (1.99e-3)" "unprognostic (3.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.25e-1)" "unprognostic (6.29e-3)" "unprognostic (6.61e-2)" "unprognostic (1.09e-2)" "unprognostic (7.82e-2)" "unprognostic (6.18e-2)" "unprognostic (1.36e-2)" "unprognostic (2.07e-1)" "unprognostic (5.89e-7)" "unprognostic (1.52e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.81e-4)" 0.3 0.2 0.9 0.0 0.9 0.1 1.8 1.2 1.9 0.1 0.1 0.8 0.1 0.1 1.4 0.0 0.7 0.0 0.1 0.9 1.0 1.5 0.0 0.5 0.0 1.0 0.9 0.4 1.0 0.3 0.0 0.1 0.9 1.3 1.9 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.1 3.3 42.4 0.8 0.0 0.3 0.6 0.0 0.2 0.0 1.9 2.9 0.3 0.2 0.5 1.6 0.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 1.5 0.1 0.3 0.0 0.8 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.2 1.9 0.9 1.0 1.0 0.9 0.9 0.8 0.8 1.9 1.2 3.2 4.6 2.3 1.0 0.4 0.5 0.4 0.0 1.7 5.5 2.2 1.1 1.5 2.1 0.0 0.0 0.3 1.2 1.4 5.9 0.2 70.5 5.4 1.7 0.8 0.0 2.7 1.9 0.4 0.4 1.9 4.1 1.6 6.3 0.2 0.4 1.1 0.3 6.7 1.6 5.3 4.1 1.0 0.7 124.8 2.5 1.1 0.0 0.0 0.2 1.0 0.0 2.0 1.1 0.4 0.4 1.2 0.7 5.6 0.9 0.5 47.0 0.7 6.6 1.0 1.7 150.2 17.1 0.0 0.6 0.3 0.9 0.5 2.7 2.3 COL16A1 ENSG00000084636 "Collagen type XVI alpha 1 chain" Q07092 1 31652263-31704319 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 109.0;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 122.0;Peritubular cells: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 133.1;ASC TERT1: 102.9;BJ hTERT+: 115.9;fHDF/TERT166: 106.5;HSkMC: 98.7;U-2197: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027237 Uncertain "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 960000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA027237: AB_10600699" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (5.64e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (2.04e-1)" "unprognostic (4.48e-3)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (4.00e-9)" "unprognostic (9.62e-2)" "unprognostic (6.13e-2)" "unprognostic (4.60e-2)" "unprognostic (2.15e-2)" 33.6 17.3 19.0 14.4 44.7 0.3 41.0 35.9 32.4 169.7 7.6 78.9 14.8 93.6 23.7 22.4 37.4 39.4 33.6 18.9 29.8 11.5 3.2 31.1 8.5 55.5 43.2 177.9 7.8 3.5 28.6 21.1 48.6 102.8 10.9 8.8 35.5 91.3 8.4 69.3 35.8 56.2 34.0 9.9 42.1 40.9 40.3 5.6 46.8 7.4 4.1 106.9 86.8 57.5 0.1 2.0 0.0 0.1 133.1 102.9 14.6 60.5 115.9 15.1 16.1 0.4 11.0 0.0 1.9 106.5 2.3 48.3 0.0 65.8 3.5 0.0 0.2 0.0 8.1 21.3 45.1 0.0 0.3 98.7 44.6 43.2 22.7 3.8 0.1 0.3 0.0 0.2 2.1 0.0 0.1 0.5 0.1 0.4 0.2 0.2 1.3 0.4 0.0 0.4 1.5 2.7 7.3 1.2 9.6 0.5 1.2 0.0 0.2 52.3 52.5 92.1 1.3 0.1 0.2 0.0 36.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 44.7 35.9 32.4 18.9 29.8 55.5 43.2 48.6 34.0 40.3 57.5 4.3 9.6 3.9 109.0 0.1 30.7 14.8 37.5 15.9 2.4 7.9 21.3 8.4 0.0 9.8 18.4 2.1 1.9 0.6 2.0 0.0 4.6 13.6 2.6 11.5 2.8 27.6 0.4 23.9 0.7 3.8 54.3 8.2 2.4 7.0 0.2 5.0 0.0 1.3 0.0 8.2 30.9 8.2 0.6 11.4 26.8 43.8 0.7 14.2 10.3 0.0 31.3 0.0 62.4 122.0 1.2 4.7 91.4 0.3 9.3 16.8 2.1 15.0 2.5 0.0 5.4 25.0 14.9 3.8 1.9 21.2 2.2 2.2 0.5 6.8 15.3 COL21A1 ENSG00000124749 "Collagen type XXI alpha 1 chain" Q96P44 6 56056590-56394094 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.1;placenta: 28.3" "Cell type enhanced" "Detected in many" "Astrocytes: 66.6;Cardiomyocytes: 36.9;Extravillous trophoblasts: 75.3;Inhibitory neurons: 63.3;Respiratory ciliated cells: 51.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 23.4;BEWO: 7.6;HSkMC: 24.0;SuSa: 11.1" "Low region specificity" "Detected in all" HPA031212 Supported Cytosol "Secreted to extracellular matrix" NA NA 290000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA031212: AB_10599941" "unprognostic (1.69e-1)" "unprognostic (4.53e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-1)" "unprognostic (1.21e-1)" "unprognostic (9.32e-3)" "unprognostic (6.84e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-3)" "unprognostic (2.17e-1)" "unprognostic (5.29e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-3)" "unprognostic (3.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-3)" 2.6 1.4 2.6 0.6 3.2 0.0 1.4 3.3 1.9 24.1 11.4 7.8 0.5 12.4 2.8 2.4 7.4 3.8 4.2 2.4 5.6 1.1 1.2 7.6 0.5 2.7 6.3 3.7 1.9 0.6 1.9 28.3 3.1 3.5 2.0 0.0 5.0 10.7 1.3 6.6 1.3 7.9 1.5 0.5 2.7 2.7 4.0 0.7 1.0 6.6 0.5 6.1 6.0 2.7 0.0 3.4 0.2 0.0 1.3 23.4 7.6 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.2 0.1 0.0 24.0 0.9 0.0 0.3 0.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.2 3.3 1.9 2.4 5.6 2.7 6.3 3.1 1.5 4.0 2.7 6.4 0.0 1.5 66.6 0.0 5.9 2.2 2.8 2.2 0.0 0.3 0.4 36.9 0.0 8.2 0.0 0.0 27.5 0.1 0.0 0.0 0.0 7.4 24.8 10.6 6.6 0.0 0.0 16.0 0.0 75.3 28.2 0.5 1.2 0.0 0.2 2.9 0.0 6.1 0.0 63.3 0.0 16.2 0.3 3.0 1.7 15.2 0.3 5.4 0.0 0.0 0.0 0.0 3.5 1.6 0.0 0.0 12.4 0.0 0.1 0.1 0.1 51.3 0.0 0.0 7.3 15.0 1.2 2.5 1.0 4.1 23.3 0.4 2.1 0.2 1.3 COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2369.0;gallbladder: 2092.8;placenta: 1981.7;smooth muscle: 2140.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2812.0;Fibroblasts: 1764.2;Smooth muscle cells: 643.0;Theca cells: 466.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 15.0;thalamus: 10.9;white matter: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 1362.4;ASC diff: 2465.0;ASC TERT1: 4252.6;fHDF/TERT166: 1815.7;HHSteC: 1690.0;HSkMC: 3189.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 61.1" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 32000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" 763.6 48.9 1.1 575.5 2.3 1.1 340.0 1.4 15.0 2369.0 11.5 275.9 84.5 768.9 60.9 298.5 177.6 2092.8 234.6 1.3 1.4 42.9 97.4 187.0 119.0 1.8 2.0 146.9 45.2 37.0 13.6 1981.7 2.2 147.5 334.7 0.0 65.6 276.9 67.1 329.8 152.5 2140.7 1.9 134.7 156.9 63.5 10.9 40.9 71.8 71.8 73.1 1097.6 273.8 4.6 0.0 0.2 1362.4 53.0 2465.0 4252.6 0.9 558.6 495.3 239.4 212.8 8.1 0.0 0.6 0.3 1815.7 0.1 0.8 1.1 1.0 26.4 0.0 0.9 0.7 228.9 0.2 1690.0 2.0 0.6 3189.5 0.0 291.5 46.9 1.0 12.5 0.0 0.4 0.0 146.4 0.0 0.2 1.4 2.6 0.1 1.7 0.3 38.5 0.5 0.0 7.2 1.3 21.1 14.5 0.4 0.0 954.8 0.1 0.0 0.7 2.3 28.0 117.3 0.5 2.8 1.3 0.4 0.5 1.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.3 1.4 15.0 1.3 1.4 1.8 2.0 2.2 1.9 10.9 4.6 111.8 3.2 13.7 0.0 0.6 171.6 0.4 1.9 3.4 0.0 7.7 9.9 11.1 0.0 1.3 0.0 0.0 57.9 1.6 0.0 0.0 2.4 29.0 75.4 2812.0 68.4 6.0 0.0 0.0 0.0 58.1 1764.2 4.1 60.7 6.3 9.7 235.2 0.9 91.1 0.0 0.2 0.0 0.0 0.6 275.3 20.8 323.1 17.5 172.5 20.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 235.9 1.5 0.6 0.0 0.2 1.6 0.0 453.6 224.3 643.0 0.9 1.5 2.2 155.7 126.3 29.1 466.8 0.0 0.4 COL5A3 ENSG00000080573 "Collagen type V alpha 3 chain" P25940 19 9959561-10010504 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Astrocytes: 510.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 38.9;BJ: 23.6;BJ hTERT+: 26.2;BJ hTERT+ SV40 Large T+: 14.4;HSkMC: 28.2;WM-115: 26.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA041695, HPA048256" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 330000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA041695: , HPA048256: AB_2680330" "unprognostic (1.17e-1)" "unprognostic (1.35e-2)" "unprognostic (4.63e-2)" "unprognostic (3.24e-2)" "unprognostic (6.84e-3)" "unprognostic (3.01e-1)" "unprognostic (7.47e-2)" "unprognostic (1.79e-2)" "unprognostic (2.36e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.17e-8)" "unprognostic (3.25e-2)" "unprognostic (7.31e-3)" "unprognostic (6.00e-2)" "prognostic unfavorable (6.87e-5)" 47.4 5.0 33.2 9.9 33.2 0.1 32.3 30.6 45.9 44.9 43.6 19.3 3.7 27.3 1.9 9.0 22.8 4.1 33.5 33.3 26.4 7.9 13.4 14.2 3.2 35.2 30.2 6.3 5.2 3.0 3.5 32.8 32.3 16.6 2.0 21.1 7.3 8.9 15.3 21.7 11.7 10.3 31.0 1.7 9.9 4.7 30.2 4.5 12.7 6.0 3.9 12.6 26.4 28.4 0.0 0.0 0.5 0.0 12.4 38.9 0.0 23.6 26.2 14.4 5.7 0.0 0.0 0.0 0.2 4.4 0.3 2.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 28.2 0.6 5.2 5.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.1 0.0 0.0 0.0 11.6 5.5 0.5 0.0 0.0 0.0 0.0 1.5 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 33.2 30.6 45.9 33.3 26.4 35.2 30.2 32.3 31.0 30.2 28.4 13.7 0.0 0.0 510.3 0.0 4.2 0.1 0.2 2.2 65.1 0.3 0.9 6.4 0.0 0.1 0.0 6.2 0.1 0.3 1.3 0.0 0.2 6.9 0.4 12.0 8.1 0.0 0.0 15.6 0.0 0.2 17.5 0.5 0.4 0.0 0.0 3.9 22.9 0.6 3.3 3.4 0.0 0.0 0.0 3.2 2.1 17.4 0.4 14.2 36.5 0.1 2.6 0.0 73.9 2.5 0.3 0.1 8.2 0.0 0.3 0.2 0.1 0.9 28.3 92.1 8.5 58.0 0.3 0.3 3.2 7.1 0.1 1.9 0.9 0.0 0.3 COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981769-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 796.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 578.3;Fibroblasts: 816.1;Leydig cells: 353.0;Peritubular cells: 251.3;Smooth muscle cells: 324.4;Theca cells: 246.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1157.2;ASC TERT1: 2331.5;BJ: 927.1;HHSteC: 1025.3;HSkMC: 1711.4;U-138 MG: 1297.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 46.8" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" NA NA 250000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" 285.9 50.1 15.7 153.3 9.0 0.7 173.9 33.9 20.4 499.3 32.1 796.8 73.3 556.3 24.6 91.1 411.5 194.4 155.6 10.3 14.9 66.1 48.3 140.3 37.5 23.1 18.4 491.4 57.8 29.1 117.8 287.1 21.5 246.8 40.5 3.4 97.7 142.3 85.4 123.4 217.7 177.9 11.3 70.7 230.5 32.8 14.9 30.7 92.6 39.5 16.6 478.7 284.7 9.7 2.9 20.2 31.2 99.6 1157.2 2331.5 3.9 927.1 586.3 231.7 80.7 16.2 62.8 0.1 75.1 522.2 183.6 4.3 13.5 2.3 19.5 0.5 14.9 0.0 3.7 5.2 1025.3 0.3 2.2 1711.4 1.0 578.6 7.8 20.9 5.6 0.2 0.7 0.6 60.9 1.4 0.3 3.2 22.4 13.4 263.2 0.1 19.5 4.3 1.6 11.1 1.0 39.9 87.6 1.1 17.9 10.4 4.2 4.2 0.5 1297.6 86.7 362.7 358.1 0.6 0.4 0.4 464.1 6.9 116.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 9.0 33.9 20.4 10.3 14.9 23.1 18.4 21.5 11.3 14.9 9.7 74.6 0.0 5.8 26.1 2.5 122.2 11.0 1.5 18.2 18.9 9.2 35.9 42.7 5.7 4.4 9.2 0.0 11.6 2.3 0.6 3.9 23.2 4.6 20.9 578.3 50.6 1.8 0.0 27.1 3.3 18.6 816.1 6.1 16.1 1.3 48.7 101.0 13.4 22.4 15.2 8.2 0.3 0.0 3.3 134.7 18.6 353.0 7.8 147.7 40.3 2.0 18.7 0.0 30.7 2.4 6.1 2.6 251.3 3.5 6.3 2.1 10.3 1.0 4.3 184.1 152.3 324.4 2.6 6.2 5.5 89.9 20.8 13.7 246.5 1.4 3.8 COL6A2 ENSG00000142173 "Collagen type VI alpha 2 chain" P12110 21 46098112-46132848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 453.2;Fibroblasts: 1455.4;Leydig cells: 605.5;Peritubular cells: 472.1;Smooth muscle cells: 555.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 4.5;MAIT T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 1155.7;ASC TERT1: 2116.9;BJ: 1073.7;BJ hTERT+: 982.8;fHDF/TERT166: 775.0;HHSteC: 1129.2;HSkMC: 1524.4;U-138 MG: 1128.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 49.6" "HPA007029, HPA030920, HPA038799" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 8200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA007029: AB_1078549, HPA030920: AB_2673659, HPA038799: AB_2676214" "unprognostic (3.53e-1)" "unprognostic (3.76e-2)" "unprognostic (3.20e-2)" "unprognostic (4.87e-2)" "unprognostic (2.92e-2)" "unprognostic (1.38e-1)" "unprognostic (2.39e-1)" "unprognostic (5.28e-3)" "unprognostic (2.11e-2)" "unprognostic (1.68e-2)" "unprognostic (1.56e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.72e-14)" "unprognostic (2.13e-2)" "unprognostic (7.61e-2)" "unprognostic (2.31e-2)" "unprognostic (2.22e-3)" 732.4 96.2 10.1 219.9 10.8 4.5 455.0 8.7 14.4 873.3 21.6 1287.5 97.7 1001.7 36.5 178.8 675.1 283.8 484.3 10.0 14.9 96.5 97.6 394.2 55.7 14.0 19.4 723.6 78.6 24.0 112.2 335.3 11.2 569.9 60.2 0.9 156.2 274.6 123.4 390.6 402.2 275.4 9.8 175.1 441.6 77.0 11.7 35.6 201.3 67.2 25.6 918.6 595.9 12.3 9.4 12.5 34.8 31.2 1155.7 2116.9 10.0 1073.7 982.8 265.5 121.5 2.3 42.4 0.2 79.2 775.0 170.8 0.9 8.1 0.7 21.7 0.8 12.3 0.2 0.2 0.2 1129.2 0.5 4.8 1524.4 0.2 503.6 10.2 0.1 0.6 0.6 0.6 0.8 108.7 5.2 0.4 2.4 19.3 0.0 130.5 0.4 66.9 1.8 0.0 0.1 1.1 54.2 41.6 0.6 0.7 19.4 1.2 6.6 0.2 1128.1 131.5 421.5 270.3 0.7 0.4 0.9 578.1 0.5 164.8 0.0 0.0 0.0 4.5 0.0 3.1 0.0 0.4 2.4 0.0 0.0 0.4 1.2 0.0 0.3 0.0 0.0 0.1 0.5 10.1 10.8 8.7 14.4 10.0 14.9 14.0 19.4 11.2 9.8 11.7 12.3 127.3 3.2 0.6 2.0 3.1 164.4 4.3 0.6 9.1 0.7 12.7 33.5 8.7 4.3 0.6 7.3 0.0 17.6 41.2 0.4 0.0 15.1 4.0 13.2 453.2 101.4 0.0 2.7 0.1 0.4 25.1 1455.4 13.3 10.3 0.0 36.1 123.1 1.4 35.3 0.0 0.8 0.1 0.0 3.1 219.7 23.7 605.5 11.7 181.5 44.0 2.4 3.1 32.0 0.0 0.1 5.9 1.0 472.1 12.1 11.2 0.0 0.4 0.1 0.5 295.9 284.8 555.2 3.7 11.5 4.6 140.4 40.4 32.7 125.3 0.4 3.9 COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414207 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 355.2;Fibroblasts: 567.9;Leydig cells: 315.1;Smooth muscle cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3311.7;ASC TERT1: 4227.5;BJ hTERT+: 1279.6;HSkMC: 2705.3" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 12.0" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 1000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" 150.8 8.3 0.1 126.5 1.0 0.4 74.5 0.2 3.0 212.6 5.2 94.8 22.9 156.3 10.2 44.1 91.8 236.4 61.2 2.4 0.1 5.7 10.3 65.8 30.7 0.6 0.1 123.8 21.1 17.3 2.8 132.9 0.7 47.7 51.7 0.0 45.2 55.4 32.5 35.7 46.6 391.3 0.8 19.0 41.5 15.6 1.8 24.8 38.1 62.3 16.1 188.4 62.7 0.9 0.2 0.5 0.6 0.0 3311.7 4227.5 60.9 815.6 1279.6 167.0 188.2 0.0 0.1 4.5 0.1 818.7 67.4 0.6 0.7 0.9 98.8 2.0 0.1 0.0 0.0 0.0 669.9 0.0 0.4 2705.3 0.0 596.3 1.8 7.8 0.2 0.0 0.1 0.6 6.2 0.0 0.1 0.2 0.5 0.0 7.4 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 17.3 0.0 0.4 2.9 19.0 45.1 27.6 142.4 1.0 0.0 0.1 859.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 3.0 2.4 0.1 0.6 0.1 0.7 0.8 1.8 0.9 48.2 0.0 10.5 0.3 0.6 61.1 0.5 0.5 1.8 1.0 2.5 2.9 10.6 1.5 3.8 0.0 0.0 4.5 1.2 0.0 0.0 0.9 5.4 11.0 355.2 17.6 0.0 0.0 0.8 0.0 6.2 567.9 6.6 8.7 1.3 1.8 25.4 1.8 8.1 0.0 0.4 0.0 0.0 1.3 85.4 9.6 315.1 5.5 72.9 29.0 2.2 1.1 1.0 0.0 0.3 2.4 0.0 103.4 2.0 0.9 0.0 0.2 1.0 2.3 32.9 19.2 197.7 1.5 1.3 3.3 61.5 5.7 9.3 48.7 0.0 1.0 CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593999-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "heart muscle: 56.9" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 69.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC TERT1: 44.0" "Region enhanced" "Detected in some" "basal ganglia: 2.6" "Low region specificity" "Detected in some" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" Yes No "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: AB_2686324" "unprognostic (1.05e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-1)" "unprognostic (3.58e-4)" "unprognostic (3.19e-1)" "unprognostic (3.67e-2)" "unprognostic (8.22e-2)" "unprognostic (9.78e-2)" "unprognostic (6.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (5.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.33e-2)" 0.4 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 2.1 0.6 0.3 0.1 4.5 0.6 0.9 1.4 4.5 56.9 0.0 0.3 1.0 0.1 1.9 0.0 0.7 0.6 0.5 0.2 1.1 1.9 0.4 0.1 2.3 0.0 0.3 0.4 6.1 0.1 7.5 0.3 0.7 0.1 1.1 0.5 2.5 0.3 0.1 0.1 0.1 0.1 1.2 3.9 0.1 0.0 0.0 0.1 0.3 10.3 44.0 0.0 2.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.7 0.6 0.1 0.1 0.3 0.1 0.3 0.0 7.5 1.0 0.0 3.8 0.3 0.0 0.0 1.0 8.3 0.3 69.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 1.3 1.0 0.0 0.0 6.5 0.0 0.0 9.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 10.8 0.0 0.0 0.6 5.5 2.0 4.7 0.1 5.4 1.0 0.0 0.7 0.0 2.0 3.9 0.0 0.0 2.6 0.0 0.6 0.0 0.2 0.0 0.3 0.0 0.3 2.3 4.6 4.4 0.1 2.7 0.0 0.6 0.1 0.0 0.3 CORO2B "ClipinC, KIAA0925" ENSG00000103647 "Coronin 2B" Q9UQ03 15 68578993-68727806 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.4;retina: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 57.1;Bipolar cells: 43.2;Cone photoreceptor cells: 37.5;Excitatory neurons: 96.6;Inhibitory neurons: 50.0;Oligodendrocytes: 146.4" "Group enriched" "Detected in many" 8 "glioma: 34.7;melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Lineage enriched" "Detected in single" 13 "B-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 26.8;ASC TERT1: 57.5;HSkMC: 41.6;hTEC/SVTERT24-B: 34.6;U-87 MG: 59.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017960 Enhanced Supported Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Focal adhesion sites" "HPA017960: AB_1847167" "unprognostic (1.35e-1)" "unprognostic (2.63e-2)" "unprognostic (2.81e-3)" "unprognostic (4.71e-3)" "unprognostic (3.28e-1)" "unprognostic (8.11e-5)" "unprognostic (4.77e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-3)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" "unprognostic (1.10e-2)" "unprognostic (5.83e-2)" "unprognostic (3.59e-2)" "unprognostic (1.87e-2)" 10.9 3.5 44.1 2.0 60.9 0.7 7.2 62.1 66.5 7.2 28.2 5.9 1.2 7.5 2.2 1.4 27.5 4.7 16.4 48.1 43.5 9.2 1.3 5.1 1.8 62.4 62.7 14.9 2.2 0.5 3.5 3.2 58.0 4.3 1.5 45.2 2.7 4.9 2.6 4.1 2.8 6.3 51.9 3.9 3.1 1.0 66.5 1.3 6.1 4.5 0.8 4.1 3.7 83.4 0.6 0.8 26.2 2.2 26.8 57.5 0.0 13.7 15.0 2.3 3.2 0.3 3.0 3.5 1.6 2.3 3.7 0.2 1.0 0.3 9.5 0.0 1.2 0.0 0.0 1.2 9.8 0.0 0.4 41.6 0.3 34.6 2.0 20.4 1.0 0.0 0.0 0.1 24.4 0.1 0.0 0.1 6.5 0.0 0.1 2.2 0.1 1.2 3.7 0.0 15.3 0.3 0.2 0.0 7.8 4.8 0.0 3.1 0.2 7.8 8.9 1.7 18.3 0.0 0.0 3.5 59.2 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.1 60.9 62.1 66.5 48.1 43.5 62.4 62.7 58.0 51.9 66.5 83.4 2.8 0.0 0.0 57.1 1.1 1.0 0.4 0.0 0.0 43.2 0.1 1.0 1.5 0.0 0.0 7.3 37.5 0.0 0.0 0.0 0.0 3.8 0.4 2.1 11.6 3.0 3.6 0.0 96.6 0.6 0.0 8.0 0.0 0.3 0.0 0.9 6.4 0.0 0.2 0.0 50.0 0.3 0.0 0.3 0.7 0.7 7.8 0.3 7.2 11.2 0.1 12.5 0.0 17.1 146.4 0.6 0.0 0.4 0.0 0.1 0.0 0.1 8.1 21.4 6.6 1.4 2.1 0.2 0.5 0.1 0.9 0.0 0.1 7.5 0.0 0.1 COX7A1 "COX7A, COX7AH" ENSG00000161281 "Cytochrome c oxidase subunit 7A1" P24310 19 36150922-36152449 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 18 "heart muscle: 2260.5;skeletal muscle: 6947.0;tongue: 4960.0" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 21879.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 162.5;ASC TERT1: 122.3;BJ: 84.7;BJ hTERT+: 102.7;fHDF/TERT166: 178.6;HHSteC: 91.4;HSkMC: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (5.48e-2)" "unprognostic (1.19e-1)" "unprognostic (6.13e-3)" "unprognostic (6.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (9.93e-2)" "unprognostic (1.92e-1)" "unprognostic (1.41e-1)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (7.84e-3)" "unprognostic (7.27e-3)" "unprognostic (9.44e-2)" "unprognostic (6.23e-2)" "unprognostic (1.54e-2)" 269.2 91.5 197.5 20.4 198.8 2.1 105.9 195.3 256.5 70.6 197.2 122.8 14.9 54.6 39.3 82.3 57.8 31.9 2260.5 210.0 214.7 86.9 11.9 63.3 12.0 197.7 188.7 46.0 40.6 147.8 105.6 27.4 199.5 86.6 23.7 49.7 88.0 119.1 6947.0 33.8 36.7 85.1 192.1 34.4 46.7 9.7 200.0 85.8 54.8 4960.0 7.3 88.5 50.1 217.9 0.5 5.9 0.6 0.1 162.5 122.3 0.0 84.7 102.7 3.4 0.0 0.0 1.8 1.4 13.0 178.6 0.0 0.7 0.0 0.0 0.8 0.2 1.8 0.4 2.1 0.3 91.4 0.0 0.8 109.0 0.0 0.0 0.0 0.0 11.3 0.0 0.6 0.7 0.0 0.8 0.0 0.7 1.0 0.6 1.2 0.2 0.0 0.4 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.2 0.6 0.1 20.7 0.0 1.3 0.5 0.4 0.8 1.9 0.7 0.2 0.8 1.2 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 197.5 198.8 195.3 256.5 210.0 214.7 197.7 188.7 199.5 192.1 200.0 217.9 309.7 0.0 5.1 2.3 2.2 26.4 1.0 28.2 2.8 80.6 25.0 89.4 21879.1 18.6 11.0 22.0 45.9 1.0 1.5 0.0 817.8 13.7 17.0 6.0 124.6 360.4 0.0 5.3 5.9 14.1 0.7 602.1 0.5 3.7 45.0 5.5 259.5 7.3 24.0 67.3 4.3 0.0 26.4 10.7 30.5 90.8 224.6 5.2 284.6 3.7 0.0 31.5 0.0 2.0 2.3 6.2 0.0 281.3 1.5 3.5 0.0 183.1 10.7 84.7 184.1 328.4 463.4 2.0 3.8 4.3 19.0 1.9 4.8 17.3 0.1 0.8 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 156.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.0;Alveolar cells type 2: 362.2;Kupffer cells: 368.5;Sertoli cells: 762.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.0;intermediate monocyte: 14.5;myeloid DC: 16.6;non-classical monocyte: 7.4" "Group enriched" "Detected in many" 5 "dendritic cells: 16.6;monocytes: 21.0" "Group enriched" "Detected in many" 4 "ASC diff: 71.1;ASC TERT1: 50.0;HSkMC: 91.2;SiHa: 68.9;THP-1: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 156.1 11.5 6.4 14.4 13.3 3.5 40.2 10.1 10.5 14.4 3.8 33.5 4.4 23.9 0.9 10.1 16.2 16.1 4.6 7.6 10.2 41.3 26.5 59.3 16.1 19.3 11.5 18.0 13.0 12.0 1.0 70.1 11.9 14.7 26.6 6.7 4.1 2.8 5.8 21.7 5.9 6.4 7.5 19.4 15.3 5.4 28.0 4.3 7.5 9.7 10.5 9.3 5.7 23.5 0.1 4.0 0.1 0.0 71.1 50.0 0.7 9.8 1.1 1.7 2.3 3.2 4.1 0.5 9.6 1.4 4.1 0.0 1.4 2.7 4.1 0.1 2.7 0.0 15.1 0.3 0.4 1.2 1.9 91.2 0.6 1.0 2.0 8.6 0.0 0.3 0.0 0.1 7.3 1.7 0.0 0.7 1.7 0.0 5.2 3.1 0.6 0.0 7.2 5.9 0.4 0.2 68.9 10.7 7.9 5.5 1.2 26.5 0.2 1.2 7.5 0.5 0.2 0.4 0.5 13.1 4.3 13.1 5.9 0.6 21.0 0.1 0.2 14.5 0.0 1.8 1.5 0.1 16.6 3.5 0.9 0.2 1.6 0.5 7.4 1.1 1.9 7.3 6.4 13.3 10.1 10.5 7.6 10.2 19.3 11.5 11.9 7.5 28.0 23.5 83.3 359.0 362.2 34.6 4.9 12.4 3.5 6.1 0.6 3.3 7.8 8.9 2.6 135.8 70.1 51.5 0.0 32.3 1.1 97.5 29.4 57.9 16.6 100.9 8.3 29.0 10.8 3.6 1.2 212.5 59.9 14.1 4.6 237.1 112.5 6.7 73.9 36.6 134.6 0.0 1.3 28.7 0.0 368.5 36.3 17.5 105.0 202.2 10.6 19.7 23.3 68.9 1.0 23.1 161.8 68.0 65.9 79.0 2.4 38.7 1.9 63.7 16.4 5.7 762.6 7.2 126.9 0.6 3.9 2.4 9.9 172.4 14.5 46.3 32.7 2.8 CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 225.9" "Cell type enhanced" "Detected in all" "Astrocytes: 150.2;Oligodendrocytes: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 250.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 116.1;ASC TERT1: 131.4;hTERT-RPE1: 108.2;Karpas-707: 97.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 51000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favorable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" 46.2 35.9 22.6 25.4 33.9 31.8 34.7 28.0 26.7 75.1 20.6 39.6 29.3 46.0 36.2 25.9 39.8 57.8 51.8 21.6 27.0 80.5 70.0 32.3 22.8 32.6 27.5 87.4 46.7 60.7 25.6 39.2 33.2 40.2 33.1 16.8 32.8 54.2 13.3 20.6 35.0 64.7 25.9 31.3 32.1 13.9 30.3 8.2 225.9 33.2 17.0 46.3 38.6 38.6 0.6 2.1 2.1 0.1 116.1 131.4 0.5 35.3 55.6 12.8 26.5 2.0 0.9 0.4 27.2 59.0 15.7 1.0 2.4 2.8 12.0 31.4 4.4 28.4 1.5 17.7 25.6 4.9 37.0 69.6 6.5 15.0 3.7 108.2 6.0 0.1 27.1 97.0 29.4 1.2 0.5 14.1 2.5 0.2 5.2 4.3 0.0 0.6 26.7 13.2 2.4 0.3 10.2 0.4 28.2 25.8 12.3 28.6 21.3 51.9 4.9 0.8 11.5 7.9 0.9 0.3 32.2 21.6 33.5 32.0 71.3 45.1 27.3 49.6 27.6 5.4 20.3 24.0 51.8 7.4 17.6 24.6 250.5 25.9 47.5 14.8 22.2 40.6 22.6 33.9 28.0 26.7 21.6 27.0 32.6 27.5 33.2 25.9 30.3 38.6 46.6 12.8 12.5 150.2 11.7 19.4 25.7 21.3 9.6 12.7 12.1 27.9 27.2 42.9 13.9 47.8 29.2 12.1 40.8 9.3 17.6 22.7 5.0 6.6 43.3 27.1 13.8 7.2 24.0 10.7 1.8 123.8 10.7 8.6 38.0 43.1 51.0 48.3 54.0 10.1 31.3 7.9 24.4 56.0 44.9 9.0 72.4 39.4 78.2 131.2 33.7 43.4 39.1 44.7 299.6 11.7 9.5 73.0 11.9 12.4 42.4 56.0 9.7 16.3 52.6 71.1 67.8 5.6 3.4 2.8 13.1 6.0 23.8 38.6 12.2 13.5 CRLF1 "CISS, CISS1, CLF, CLF-1" ENSG00000006016 "Cytokine receptor like factor 1" O75462 19 18572220-18607741 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 88.5" "Cell type enhanced" "Detected in some" "Astrocytes: 15.3;Basal keratinocytes: 9.7;Fibroblasts: 16.0;Respiratory ciliated cells: 11.9;Skeletal myocytes: 19.9;Smooth muscle cells: 10.5" "Group enriched" "Detected in all" 4 "lung cancer: 27.4;thyroid cancer: 36.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "ASC diff: 1048.7;Hep G2: 458.8" "Region enriched" "Detected in many" 7 "hippocampal formation: 21.1" "Group enriched" "Detected in some" 6 "cerebellum: 2.3;spinal cord: 8.6" "HPA041493, HPA041793" Approved "Secreted in other tissues" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041493: AB_10795637, HPA041793: AB_10804117" "unprognostic (1.97e-1)" "unprognostic (2.29e-1)" "unprognostic (2.34e-3)" "unprognostic (9.31e-3)" "unprognostic (1.58e-2)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (4.69e-2)" "unprognostic (3.34e-3)" "unprognostic (4.95e-2)" "unprognostic (7.92e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.86e-2)" "unprognostic (5.27e-3)" 40.1 14.5 18.7 0.9 24.6 0.0 18.7 22.4 51.7 25.7 11.2 8.9 0.5 12.8 0.9 17.4 11.3 1.4 88.5 22.0 13.5 7.7 1.5 16.0 0.4 24.3 28.0 4.5 8.9 0.5 8.9 11.3 17.8 8.9 0.4 0.1 14.9 6.2 21.4 27.3 5.0 1.5 18.7 2.4 7.5 1.3 13.4 0.3 50.3 0.9 0.2 9.3 15.5 25.5 0.0 0.0 0.0 10.7 1048.7 15.3 5.2 5.4 0.0 0.0 0.0 0.1 0.0 0.0 66.5 33.2 1.9 0.4 10.8 0.2 0.0 0.0 1.4 0.0 18.1 458.8 7.5 0.1 0.5 12.0 1.0 0.2 0.3 1.6 0.3 0.0 0.1 0.2 0.3 16.6 0.0 0.0 1.2 0.1 0.3 0.0 9.1 0.1 0.0 0.5 0.0 0.1 14.2 0.0 0.0 2.0 13.0 0.6 1.3 0.1 11.1 0.8 0.4 0.1 0.0 0.5 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 24.6 22.4 51.7 22.0 13.5 24.3 28.0 17.8 18.7 13.4 25.5 0.4 0.0 0.0 15.3 0.3 9.7 0.6 6.8 0.0 0.2 0.7 4.2 2.5 0.0 2.6 0.0 0.0 0.1 0.3 0.1 5.9 0.3 6.9 2.6 1.9 0.5 0.0 0.0 7.8 0.2 1.3 16.0 0.5 0.5 0.0 0.2 0.4 0.1 0.3 0.0 1.0 0.0 2.0 0.0 1.0 0.4 0.0 0.4 0.0 0.0 0.1 0.9 1.0 0.5 0.8 0.2 0.0 0.0 0.0 0.3 0.0 0.3 11.9 1.3 0.0 19.9 10.5 0.2 2.2 0.6 4.5 0.3 0.6 0.2 0.1 0.3 CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.6" "Group enriched" "Detected in all" 5 "dendritic cells: 306.9;monocytes: 377.6" "Cell line enhanced" "Detected in all" "ASC diff: 795.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: AB_10960991, HPA044150: AB_10959594" "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.85e-3)" "unprognostic (7.36e-2)" "unprognostic (4.73e-3)" "unprognostic (4.28e-2)" "unprognostic (1.87e-1)" "unprognostic (9.97e-2)" "unprognostic (4.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (9.93e-2)" "unprognostic (1.28e-3)" 157.2 106.5 65.2 38.7 69.2 43.2 123.9 51.9 54.8 211.2 52.9 145.1 35.0 170.1 57.1 58.7 138.3 80.5 83.9 49.6 64.9 67.9 44.6 92.3 37.3 65.2 62.4 131.4 36.0 45.7 22.8 69.9 63.9 90.7 51.6 19.3 54.0 106.5 54.4 84.1 65.6 115.0 67.5 48.2 78.9 25.0 65.3 23.7 77.2 68.9 38.1 142.7 135.8 69.5 64.1 123.3 37.8 119.2 795.0 516.6 219.0 136.1 294.0 160.6 151.9 42.1 35.1 44.4 147.6 259.3 129.9 80.2 68.0 103.9 115.5 110.1 106.0 69.2 87.6 43.7 237.4 45.4 54.8 415.3 208.5 145.0 183.2 311.7 172.0 27.0 60.3 82.1 164.6 54.7 16.5 46.3 45.5 67.5 165.7 59.4 111.0 86.1 127.8 42.0 7.9 61.0 92.0 79.8 201.1 87.3 85.9 109.3 113.0 209.1 89.1 115.4 145.9 59.0 214.3 6.7 164.3 89.7 117.1 13.4 377.6 28.5 35.8 147.7 52.5 39.9 51.4 40.2 306.9 39.2 29.2 27.8 30.5 42.1 46.0 82.5 74.0 200.5 65.2 69.2 51.9 54.8 49.6 64.9 65.2 62.4 63.9 67.5 65.3 69.5 74.0 9.6 42.8 15.3 29.0 60.4 41.1 39.5 150.8 17.9 32.7 43.7 34.7 25.8 22.0 38.6 8.4 49.0 37.1 14.8 11.7 25.0 1.2 17.4 135.7 72.7 6.0 46.0 10.0 32.0 81.6 142.3 29.0 31.2 48.1 58.4 122.4 53.2 107.0 35.3 14.5 26.0 10.2 181.1 91.1 6.3 142.9 108.6 80.0 10.3 134.1 15.9 22.6 17.1 11.6 18.4 16.3 144.8 58.1 24.5 24.4 52.7 6.8 10.1 111.7 78.4 120.9 1.6 15.9 95.1 46.7 28.0 26.5 89.9 36.1 30.0 CRY2 ENSG00000121671 "Cryptochrome circadian regulator 2" Q49AN0 11 45847118-45883248 "Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 141.9;Horizontal cells: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037577 Supported Supported "Nuclear speckles,Cytosol" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Nuclear speckles" Cytosol "HPA037577: AB_10672497" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (1.31e-2)" "unprognostic (9.16e-2)" "unprognostic (3.09e-2)" "prognostic favorable (6.82e-5)" "unprognostic (1.48e-3)" "unprognostic (1.67e-1)" "unprognostic (5.07e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.01e-1)" "prognostic favorable (6.44e-15)" "unprognostic (8.13e-3)" "unprognostic (1.89e-1)" "unprognostic (4.24e-2)" "unprognostic (2.24e-1)" 31.8 22.3 33.3 8.9 35.3 29.4 27.1 36.4 36.9 24.4 22.8 26.5 10.8 23.3 16.9 15.9 29.1 17.4 60.0 36.6 29.3 22.5 62.7 22.9 10.4 27.4 31.5 38.7 34.7 22.4 30.8 13.5 28.5 25.3 9.9 52.8 21.7 22.1 96.7 50.4 16.7 17.1 28.8 14.0 24.6 34.4 35.2 12.6 34.0 64.8 10.3 26.0 18.4 31.4 1.4 4.2 6.3 7.5 16.7 8.4 13.8 5.0 8.9 6.2 4.5 6.8 3.3 9.8 3.8 10.5 5.9 8.5 6.0 5.2 4.3 9.8 5.5 6.4 8.2 9.4 6.4 8.0 8.5 9.9 7.5 4.8 7.6 7.0 4.4 7.5 12.7 16.2 5.6 5.3 6.8 9.4 17.1 17.8 5.0 11.5 9.1 4.6 4.5 7.8 10.1 3.8 8.3 7.5 4.5 8.0 10.0 5.5 5.5 8.7 5.3 13.5 3.6 15.0 10.8 7.9 5.3 3.5 5.3 4.1 3.5 5.4 5.7 4.8 4.7 5.0 5.5 6.1 3.6 4.6 6.6 6.9 1.8 7.5 8.0 2.6 4.9 5.3 33.3 35.3 36.4 36.9 36.6 29.3 27.4 31.5 28.5 28.8 35.2 31.4 11.7 12.8 18.2 48.0 12.6 17.0 9.7 5.1 8.0 141.9 10.6 8.6 34.7 14.3 11.6 7.3 27.1 8.0 10.0 17.2 29.4 5.4 24.2 28.1 7.5 9.2 7.1 3.0 30.3 4.7 5.6 19.8 12.8 15.4 14.7 10.8 8.6 47.3 3.6 101.0 26.0 7.4 6.1 8.5 12.5 8.7 31.4 7.2 16.0 10.3 6.2 34.4 10.3 13.0 13.6 6.0 6.0 39.9 8.5 11.6 10.5 11.6 23.8 27.5 19.7 14.5 14.6 29.1 15.0 4.4 17.5 9.3 9.1 8.4 6.0 9.8 CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5623.2;heart muscle: 10683.1;skeletal muscle: 6972.0;tongue: 9406.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 2889.5;Cardiomyocytes: 6878.2;Muller glia cells: 1664.3;Proximal tubular cells: 7285.9" "Group enriched" "Detected in all" 6 "glioma: 426.4;renal cancer: 575.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "ASC diff: 2663.1;fHDF/TERT166: 775.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB002053: AB_442024, CAB040560: , HPA057100: AB_2683337" "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.90e-5)" "unprognostic (2.46e-2)" "unprognostic (3.02e-2)" "unprognostic (8.41e-3)" "unprognostic (9.29e-3)" "unprognostic (7.35e-2)" "unprognostic (8.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.68e-2)" "unprognostic (7.02e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (8.83e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.70e-5)" 1035.0 106.6 2466.0 113.9 3113.8 0.4 592.2 3032.2 5623.2 439.1 2077.7 678.9 24.6 351.4 179.1 312.2 204.0 71.7 10683.1 2424.9 2666.2 2123.2 37.2 253.4 15.0 3215.2 2856.7 136.0 50.6 24.9 209.2 107.8 3147.1 317.9 78.2 478.7 428.7 358.5 6972.0 317.3 158.5 338.1 2877.3 88.5 263.8 23.5 2815.5 20.9 477.7 9406.7 34.4 490.0 477.5 4060.6 0.1 0.5 0.1 45.0 2663.1 90.9 15.0 54.5 2.5 0.8 2.5 1.7 0.2 0.0 41.7 775.8 0.2 2.0 1.8 2.3 1.4 0.3 0.0 0.0 11.9 3.9 16.9 0.4 0.7 77.1 11.1 0.6 6.2 44.3 0.2 0.0 4.6 2.5 169.5 0.1 0.1 1.1 0.5 0.0 1.0 0.2 0.0 0.6 29.8 0.8 0.1 0.4 5.3 9.1 39.8 63.5 4.9 0.0 1.7 310.1 105.0 6.5 4.1 0.5 0.1 0.6 7.1 0.4 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2466.0 3113.8 3032.2 5623.2 2424.9 2666.2 3215.2 2856.7 3147.1 2877.3 2815.5 4060.6 38.4 83.3 4.1 96.0 51.3 174.9 2889.5 32.1 72.8 16.2 334.4 696.1 6878.2 84.4 15.2 1338.9 18.8 3.9 6.8 0.4 677.0 320.3 24.7 345.4 265.3 88.4 7.1 0.0 6.7 11.5 7.4 880.6 0.0 1008.4 0.0 16.1 35.7 0.7 5.8 10.1 12.6 2.4 8.2 0.3 85.8 12.6 228.6 67.7 483.8 11.2 3.6 1664.3 0.0 7.5 615.7 12.1 0.0 187.7 1.6 855.4 0.0 7285.9 23.2 59.4 138.1 799.9 1053.3 21.6 1.4 56.5 155.1 33.4 55.4 6.7 1.2 249.0 CSAD "CSD, PCAP" ENSG00000139631 "Cysteine sulfinic acid decarboxylase" Q9Y600 12 53157663-53180925 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 16.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.3" "Cell line enhanced" "Detected in all" "ASC diff: 84.5;T-47d: 52.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039487 Approved "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "HPA039487: AB_10672776" "unprognostic (1.00e-1)" "unprognostic (3.28e-2)" "prognostic unfavorable (9.50e-4)" "unprognostic (1.57e-1)" "unprognostic (7.99e-2)" "prognostic favorable (6.33e-4)" "prognostic favorable (1.37e-4)" "unprognostic (2.46e-2)" "unprognostic (7.87e-3)" "unprognostic (1.01e-1)" "prognostic favorable (3.39e-4)" "unprognostic (3.48e-2)" "prognostic unfavorable (1.93e-6)" "unprognostic (4.59e-2)" "unprognostic (3.47e-1)" "unprognostic (1.38e-1)" "prognostic favorable (6.81e-6)" 68.0 28.3 24.3 15.9 25.4 39.1 62.4 25.2 25.7 54.9 33.8 34.3 17.3 31.2 52.3 29.3 41.5 19.2 25.2 24.0 24.5 39.2 101.7 30.8 19.1 26.1 23.0 54.0 35.9 14.9 40.9 13.0 24.8 50.3 16.0 16.8 34.7 19.8 19.6 59.6 28.5 19.6 20.2 37.5 31.9 27.7 24.7 14.2 36.0 7.7 14.1 25.8 37.6 36.7 3.7 6.8 16.0 6.8 84.5 34.4 5.7 14.5 3.2 6.0 5.0 4.1 8.8 4.9 10.6 7.7 2.0 12.6 7.1 11.2 3.5 6.6 8.6 7.8 19.4 8.8 7.6 3.3 4.9 42.6 13.8 9.0 11.2 30.8 5.6 10.4 8.4 42.8 5.7 30.8 1.8 9.2 3.1 1.9 6.3 6.6 1.0 11.4 8.0 9.6 8.0 6.3 14.3 19.9 5.7 9.9 52.7 6.5 12.6 17.5 3.4 5.2 4.2 12.2 3.4 2.6 14.7 8.3 7.1 3.7 2.0 2.5 1.3 1.1 0.8 1.1 1.8 0.8 1.0 1.8 2.4 1.4 16.3 1.6 1.3 2.3 3.4 0.5 24.3 25.4 25.2 25.7 24.0 24.5 26.1 23.0 24.8 20.2 24.7 36.7 23.5 3.2 22.0 40.1 15.6 16.6 28.3 18.3 4.0 29.0 27.9 43.4 8.9 20.0 17.4 23.9 16.7 12.2 18.5 19.3 3.9 12.6 0.7 11.6 20.4 22.5 14.4 0.4 47.0 9.1 6.9 23.0 19.4 14.3 9.5 22.0 21.4 38.2 8.4 26.9 51.1 21.3 14.2 11.9 12.8 3.5 27.1 11.1 14.2 30.0 15.6 18.3 20.6 34.2 62.4 10.0 25.5 30.9 6.9 28.8 22.5 5.1 15.4 30.0 39.5 22.5 27.9 48.0 64.4 5.5 18.3 8.9 13.0 17.9 15.4 24.2 CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 58.9;granulocytes: 113.5;Hepatic stellate cells: 53.2;Sertoli cells: 59.2;Skeletal myocytes: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Cell line enhanced" "Detected in many" "ASC diff: 220.0;BJ hTERT+: 149.5;GAMG: 142.1;HHSteC: 338.7;HSkMC: 216.4;hTERT-RPE1: 153.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" NA NA 270000 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies" "HPA076624: AB_2686810" "unprognostic (2.35e-3)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.19e-1)" "unprognostic (3.60e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.04e-1)" "unprognostic (1.75e-2)" "unprognostic (2.18e-1)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (1.00e-11)" "unprognostic (2.03e-1)" "unprognostic (1.88e-2)" "unprognostic (4.01e-1)" "unprognostic (3.16e-2)" 67.4 37.5 27.5 24.5 32.9 18.4 46.4 36.9 25.8 25.0 32.9 26.8 13.3 21.1 5.2 15.6 28.5 31.9 29.0 24.5 30.9 17.3 16.4 47.6 28.2 42.3 32.6 22.1 17.5 10.5 8.7 41.2 36.1 21.4 16.2 1.5 18.9 16.6 11.4 19.4 26.7 17.6 36.0 48.0 22.0 3.7 32.2 13.5 22.2 11.3 12.2 42.0 29.6 46.5 9.3 29.3 14.7 5.7 220.0 138.3 5.7 36.0 149.5 25.9 23.9 1.3 4.5 0.2 47.0 80.1 142.1 6.8 5.7 11.0 9.4 99.5 5.3 10.9 17.3 10.3 338.7 0.0 13.7 216.4 3.2 57.5 33.0 153.1 5.4 2.8 2.9 5.5 31.2 0.5 0.3 1.8 5.3 2.4 3.1 1.0 8.4 0.9 10.9 7.9 0.5 1.6 9.7 2.6 12.6 16.7 2.3 1.0 19.2 27.8 10.5 123.7 22.1 2.8 1.1 0.3 70.7 0.1 106.6 13.2 0.0 22.3 0.3 0.0 0.6 0.0 0.9 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.3 0.2 27.5 32.9 36.9 25.8 24.5 30.9 42.3 32.6 36.1 36.0 32.2 46.5 30.6 9.6 35.5 11.8 2.3 7.4 5.1 7.9 13.1 0.3 10.0 9.3 3.2 14.3 5.3 3.7 0.0 0.8 2.0 0.6 0.0 40.4 0.4 20.6 9.3 21.6 7.8 11.1 0.3 2.3 0.5 58.9 4.6 24.8 113.5 0.3 53.2 3.0 9.2 0.0 1.0 0.8 0.0 3.5 13.1 0.3 25.1 8.2 10.6 28.1 1.6 1.8 0.0 3.0 17.5 9.3 1.6 8.6 1.9 8.0 1.2 0.9 1.1 0.2 59.2 94.4 37.1 0.6 0.7 5.6 5.5 0.8 20.9 0.7 1.0 2.6 CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4217.6" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 18746.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4967.5;intermediate monocyte: 6424.5;myeloid DC: 7959.0;non-classical monocyte: 4297.7;plasmacytoid DC: 4427.4" "Group enriched" "Detected in all" 9 "dendritic cells: 7959.0;monocytes: 6424.5" "Cell line enhanced" "Detected in many" "ASC diff: 1733.4;ASC TERT1: 1179.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1040000000 2800000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" 1046.2 707.6 3041.2 262.3 3117.9 170.8 900.3 2823.3 4217.6 587.8 3094.8 788.7 389.6 708.3 875.9 557.1 802.7 583.0 1275.3 2976.3 2707.6 517.4 833.6 595.8 463.5 3258.4 3096.2 575.8 944.1 320.0 670.1 165.9 2939.3 773.9 416.9 46.9 2008.0 441.5 749.0 497.1 800.3 367.6 3028.1 723.7 979.9 761.3 3302.7 418.9 658.8 517.4 208.1 703.0 618.4 2883.1 155.2 328.2 75.4 175.8 1733.4 1179.8 145.3 261.4 350.7 170.3 137.7 625.1 219.7 0.8 241.0 345.2 221.3 496.2 69.6 499.9 51.9 0.9 253.5 157.6 61.1 1082.9 621.2 7.5 251.0 919.0 415.9 226.6 241.5 352.5 268.5 18.5 147.6 4.0 239.5 234.4 1.5 162.2 103.5 461.9 752.2 5.7 96.4 215.2 708.0 328.3 84.7 98.2 191.1 54.6 343.3 107.7 156.5 548.2 702.0 163.4 119.0 231.6 97.7 157.1 6.2 1.8 138.0 339.5 184.0 48.1 4967.5 33.2 66.9 6424.5 25.5 23.1 18.3 45.8 7959.0 13.6 16.9 31.1 809.3 191.4 4297.7 4427.4 13.6 4250.8 3041.2 3117.9 2823.3 4217.6 2976.3 2707.6 3258.4 3096.2 2939.3 3028.1 3302.7 2883.1 662.4 115.4 168.8 849.5 93.8 942.9 571.1 568.2 213.9 152.4 660.2 512.1 240.7 1361.2 514.5 641.9 29.2 476.8 603.3 1889.9 414.8 489.9 46.2 441.1 795.0 728.2 882.1 252.1 4.5 783.6 308.7 3026.2 981.7 631.0 359.9 687.0 491.9 2563.0 1816.7 48.8 11.2 1360.6 691.7 4301.1 18746.6 184.3 2132.6 4542.6 1563.5 87.1 2025.6 248.7 99.9 263.9 6.0 1458.5 2342.1 1790.4 67.9 786.0 4301.1 1098.6 364.4 36.3 2195.7 1417.0 846.2 125.5 400.6 461.5 822.0 469.0 117.4 208.1 1039.4 1079.7 CTBS CTB ENSG00000117151 Chitobiase Q01459 1 84549611-84574480 "Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 7 "basal ganglia: 7.4" "CAB017043, HPA023594, HPA048810" Approved Uncertain Cytosol "Intracellular and membrane" NA NA 370000000 "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB017043: , HPA023594: AB_1847311, HPA048810: " "unprognostic (7.76e-2)" "unprognostic (1.28e-2)" "unprognostic (1.11e-1)" "unprognostic (1.36e-1)" "unprognostic (9.36e-2)" "unprognostic (3.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.76e-1)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (9.23e-2)" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.08e-2)" "unprognostic (4.89e-2)" "unprognostic (3.12e-1)" "unprognostic (4.04e-2)" 1.5 1.4 0.4 1.4 0.8 3.3 1.6 1.0 0.6 1.2 2.1 1.2 0.9 1.5 3.1 1.0 1.1 1.2 1.0 0.2 0.6 1.7 3.7 1.4 1.6 1.3 0.9 0.8 1.7 1.6 0.5 1.2 1.5 2.2 1.4 1.4 3.3 0.8 0.8 2.4 1.2 1.1 0.5 2.5 1.4 0.5 0.8 1.0 1.3 0.9 1.0 1.0 0.5 1.3 0.9 0.3 0.2 0.2 2.7 3.2 0.6 0.6 2.2 0.3 0.8 0.1 1.1 1.2 0.2 1.4 0.3 0.4 0.0 0.9 0.9 1.1 0.3 0.8 0.1 0.1 1.6 0.8 0.4 2.4 1.6 0.8 1.2 1.9 0.9 0.5 0.7 2.2 0.6 0.0 0.5 0.9 0.2 0.2 0.3 0.2 0.3 0.8 1.9 0.4 0.1 0.4 0.2 0.9 1.1 0.5 0.5 0.9 1.5 1.1 0.1 1.5 0.7 0.6 0.2 0.3 0.8 1.1 0.8 0.5 0.1 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.3 0.1 0.0 0.0 0.4 0.8 1.0 0.6 0.2 0.6 1.3 0.9 1.5 0.5 0.8 1.3 43.6 9.6 23.4 10.4 37.4 30.3 30.2 28.0 34.1 5.9 33.1 15.6 5.8 31.5 25.5 23.9 41.7 26.8 25.4 30.2 43.0 20.2 3.3 24.1 24.4 29.9 23.0 14.1 6.2 19.2 24.2 28.1 25.0 19.4 43.8 9.7 49.6 70.8 48.2 3.3 4.3 18.9 16.2 75.5 27.9 3.7 21.1 58.8 7.2 20.6 56.5 21.8 18.6 5.5 9.0 19.1 25.2 24.5 59.8 36.7 30.0 44.4 38.2 41.9 13.1 20.2 16.6 10.4 12.8 27.3 24.7 25.6 26.8 25.3 18.4 29.9 CTF1 "CT-1, CT1" ENSG00000150281 "Cardiotrophin 1" Q16619 16 30896614-30903547 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 16.4;Cardiomyocytes: 11.4;Distal tubular cells: 31.3;Muller glia cells: 21.1;Proximal tubular cells: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.6;ASC TERT1: 14.7;fHDF/TERT166: 11.9;HHSteC: 13.0;HSkMC: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025853 Uncertain "Secreted to blood" NA NA 11900 "Cluster 6: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "CAB025853: " "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (6.81e-3)" "unprognostic (1.06e-3)" "prognostic unfavorable (7.22e-5)" "unprognostic (2.12e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.87e-4)" "unprognostic (4.47e-2)" "unprognostic (1.09e-1)" "unprognostic (6.75e-2)" "unprognostic (2.76e-2)" "unprognostic (1.76e-3)" "unprognostic (5.07e-3)" "unprognostic (2.06e-1)" "unprognostic (2.16e-2)" "unprognostic (1.79e-1)" 6.4 8.1 4.8 1.3 4.7 1.5 6.7 4.1 5.2 14.7 5.3 13.4 0.8 17.3 4.2 5.3 12.1 3.8 16.0 4.5 4.5 10.2 1.2 7.4 1.3 5.3 5.8 18.4 3.6 10.0 5.2 2.0 4.7 12.2 1.0 2.1 5.7 12.7 14.1 2.7 4.6 7.6 5.5 1.7 7.6 3.4 5.0 2.1 8.5 10.9 1.1 14.0 9.6 5.0 2.0 0.3 2.6 5.7 13.6 14.7 4.5 4.3 8.5 4.4 5.6 2.4 0.4 0.1 8.3 11.9 0.4 1.5 0.0 3.0 4.4 0.1 0.2 0.1 0.2 0.9 13.0 0.2 0.8 13.9 3.8 3.3 8.0 4.9 1.2 0.2 3.7 0.4 7.9 0.3 0.3 0.4 0.8 1.2 0.8 1.6 3.9 0.0 0.7 0.9 0.2 1.4 0.0 0.1 0.0 4.0 6.9 0.3 0.9 4.2 5.2 0.2 0.1 0.1 0.1 0.2 3.3 0.5 0.0 0.6 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.4 0.1 0.1 0.3 0.0 0.0 4.8 4.7 4.1 5.2 4.5 4.5 5.3 5.8 4.7 5.5 5.0 5.0 0.8 3.2 6.4 2.6 0.8 0.4 16.4 1.8 2.2 0.3 6.2 7.1 11.4 2.8 1.8 7.3 0.0 0.3 1.2 0.0 31.3 1.0 0.6 7.1 2.9 1.1 0.0 0.4 0.3 0.4 0.2 3.9 0.0 2.4 0.0 3.8 0.0 0.4 0.6 0.0 0.6 0.2 0.0 0.6 0.8 0.7 2.1 1.1 0.0 1.0 0.4 21.1 0.0 1.0 0.4 0.4 0.0 2.6 0.6 2.7 0.2 14.4 2.5 0.9 0.0 4.6 3.0 0.8 0.4 1.9 0.3 0.4 0.7 3.9 0.2 7.4 CTHRC1 ENSG00000164932 "Collagen triple helix repeat containing 1" Q96CG8 8 103371538-103382989 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 69.1;gallbladder: 87.8;placenta: 90.1;urinary bladder: 84.6" "Cell type enhanced" "Detected in many" "Endothelial cells: 95.2;Fibroblasts: 181.6;Langerhans cells: 45.9;Melanocytes: 49.8;Smooth muscle cells: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 294.6;fHDF/TERT166: 138.1;HHSteC: 197.1;HSkMC: 406.6;WM-115: 386.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059806, HPA061896" Approved Approved Nucleoplasm "Secreted in other tissues" NA NA 420000 "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA059806: AB_2684130, HPA061896: AB_2684633" "unprognostic (2.04e-2)" "unprognostic (4.58e-1)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (4.17e-2)" "unprognostic (3.64e-2)" "unprognostic (8.63e-2)" "unprognostic (1.12e-2)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.22e-14)" "unprognostic (2.33e-3)" "unprognostic (3.21e-2)" "unprognostic (7.96e-3)" "unprognostic (2.37e-3)" 69.1 2.8 1.6 15.4 1.8 0.5 39.0 5.7 6.3 12.8 0.4 6.6 6.3 18.7 3.3 9.7 5.3 87.8 8.9 1.5 2.3 2.3 0.8 8.9 13.8 2.0 1.6 4.2 3.7 2.2 3.7 90.1 2.5 4.7 6.2 2.4 17.0 5.6 3.6 32.5 3.5 19.7 1.8 2.6 3.6 3.6 1.5 6.2 9.1 4.1 16.0 84.6 6.6 3.3 12.1 0.9 3.3 0.8 90.6 294.6 0.2 34.8 9.3 3.7 5.0 1.1 8.3 1.5 36.6 138.1 0.2 0.4 0.1 0.2 17.7 0.5 0.0 0.5 0.6 19.2 197.1 0.9 0.7 406.6 0.5 30.7 0.4 1.4 60.2 2.3 0.5 91.6 18.7 1.7 17.2 41.1 11.0 0.4 58.0 35.8 30.9 1.1 2.9 0.2 5.7 4.3 0.1 0.2 110.8 12.6 0.1 0.2 49.0 4.6 1.8 4.8 0.4 3.0 0.8 0.6 2.2 0.2 386.9 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.2 0.0 0.1 1.6 1.8 5.7 6.3 1.5 2.3 2.0 1.6 2.5 1.8 1.5 3.3 36.9 3.2 2.3 1.0 6.7 32.0 0.2 12.1 0.0 0.3 0.9 1.4 0.8 1.5 3.6 3.7 0.0 5.6 0.9 0.0 0.0 4.1 0.5 6.4 9.8 95.2 1.2 0.8 2.3 0.6 11.3 181.6 0.0 11.5 0.0 0.5 17.5 0.1 8.0 0.0 2.0 0.0 4.1 0.3 45.9 0.8 12.5 0.9 49.8 3.7 0.6 5.5 1.0 4.5 1.8 1.8 0.0 0.4 24.2 0.8 0.0 0.5 0.8 1.2 0.0 4.7 77.4 4.3 16.5 0.3 27.3 16.6 3.5 1.2 0.2 0.5 CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 368.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 445.6;Proximal enterocytes: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 856.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068, HPA072487" Enhanced Enhanced Vesicles "Intracellular and membrane" NA NA 28000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "CAB024930: , HPA031068: AB_10601205, HPA072487: " "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" 80.4 368.3 56.8 75.3 58.1 75.6 61.9 63.6 65.6 47.6 96.0 178.6 100.9 55.1 39.0 60.4 39.3 89.7 97.2 59.7 63.8 188.1 95.7 90.9 61.6 62.6 59.1 62.2 52.9 104.4 43.8 76.4 61.4 38.5 170.4 44.0 61.3 48.4 56.0 95.2 109.2 67.3 59.4 108.5 63.3 33.5 70.2 23.0 47.4 61.7 58.8 82.8 49.2 68.4 111.9 114.1 17.6 89.2 856.5 438.6 47.0 150.3 424.0 169.6 217.5 214.4 291.8 24.1 176.2 299.9 638.1 168.6 55.9 105.6 95.7 47.6 53.6 54.3 53.4 375.9 187.3 98.0 240.9 349.0 123.6 107.9 22.5 421.9 190.1 28.2 61.0 355.1 186.9 232.1 25.8 82.4 19.4 172.6 272.1 37.8 107.3 135.7 138.2 96.7 36.9 37.8 263.2 450.3 444.4 51.5 108.5 141.8 172.5 335.0 76.2 178.9 123.7 162.1 238.5 15.7 599.3 128.6 142.4 480.7 305.9 530.5 44.9 168.8 185.5 42.0 75.6 78.3 102.4 25.7 26.6 39.8 152.4 81.2 120.1 40.6 155.4 378.1 56.8 58.1 63.6 65.6 59.7 63.8 62.6 59.1 61.4 59.4 70.2 68.4 53.7 35.3 32.6 26.1 38.2 24.2 38.9 88.8 17.6 58.4 18.4 15.9 12.6 65.8 64.1 71.7 60.5 104.1 27.5 445.6 39.2 246.0 3.3 22.3 39.5 56.0 54.0 22.1 20.4 166.4 109.2 86.8 29.6 62.4 9.5 50.8 102.1 67.9 297.1 47.1 25.2 74.5 95.6 177.1 25.1 4.8 32.9 273.1 112.1 12.2 135.6 86.6 37.0 7.1 10.2 135.0 216.0 27.4 41.9 18.6 301.8 245.8 34.2 46.1 26.3 33.7 54.5 15.3 31.9 24.0 22.9 144.1 49.1 91.3 113.9 36.2 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 563.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1081.6;Extravillous trophoblasts: 1012.3;Hepatic stellate cells: 580.4;Hofbauer cells: 1105.7;Macrophages: 537.2;Syncytiotrophoblasts: 1543.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.1;non-classical monocyte: 195.2" "Lineage enriched" "Detected in many" 12 "monocytes: 195.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 2305.0;HSkMC: 1061.0" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 17000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 232.4 86.6 49.2 136.0 55.4 84.8 110.0 52.9 67.5 69.5 67.9 110.3 39.7 108.1 81.6 33.3 108.4 85.0 112.5 47.0 52.3 207.3 333.5 154.9 101.1 54.4 54.0 96.4 61.9 151.1 69.5 563.6 57.5 68.2 58.8 32.3 77.6 91.7 71.9 39.8 57.1 125.2 52.4 124.4 71.4 80.1 112.2 33.0 76.1 79.8 49.4 209.8 48.0 59.6 88.1 423.0 32.6 55.3 514.0 2305.0 198.4 267.2 781.8 232.2 300.6 43.0 86.3 0.0 128.9 355.4 754.0 67.5 49.8 86.0 198.4 1.9 37.8 18.1 111.2 105.1 352.6 0.1 51.4 1061.0 138.9 373.7 134.9 186.6 194.9 0.0 162.5 0.7 326.6 115.6 0.5 9.9 67.7 128.6 77.5 21.6 21.5 0.6 158.6 39.0 42.8 50.6 62.1 133.5 312.3 177.9 14.5 97.9 296.9 190.8 104.7 750.6 125.9 18.5 84.1 0.9 692.6 0.2 67.9 0.3 13.5 0.6 0.3 128.1 0.0 0.0 6.6 0.1 7.9 0.1 16.7 1.3 0.5 0.2 195.2 0.3 1.7 10.1 49.2 55.4 52.9 67.5 47.0 52.3 54.4 54.0 57.5 52.4 112.2 59.6 86.1 41.7 52.9 15.3 11.2 37.7 82.1 58.0 15.4 43.8 12.2 33.4 96.8 87.2 46.4 75.4 18.8 1081.6 0.3 16.3 27.4 91.8 5.3 48.1 119.9 110.0 11.5 251.2 18.6 93.4 1012.3 261.7 10.2 27.6 29.7 63.6 580.4 122.6 1105.7 13.5 24.0 8.5 20.3 206.9 105.4 17.4 156.9 537.2 64.0 14.0 16.2 79.5 0.0 17.6 31.7 67.2 5.6 187.3 1.9 34.5 8.0 138.3 67.3 45.4 92.1 176.9 136.3 207.4 60.5 6.8 34.0 1543.6 10.8 30.8 11.7 44.8 CXCL12 "PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1" ENSG00000107562 "C-X-C motif chemokine ligand 12" P48061 10 44370165-44386493 "Predicted secreted proteins" "Chemotaxis, Host-virus interaction" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 347.2;Distal tubular cells: 172.1;Fibroblasts: 566.4;Kupffer cells: 191.8;Smooth muscle cells: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 509.6;BJ hTERT+: 303.5;BJ hTERT+ SV40 Large T+: 294.9;BJ hTERT+ SV40 Large T+ RasG12V: 441.2;fHDF/TERT166: 501.8;HSkMC: 1293.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017564 Approved "Secreted to blood" NA NA 1030000 560000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017564: AB_2088170" "unprognostic (2.41e-1)" "unprognostic (2.95e-2)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-2)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-3)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" 366.8 82.6 19.4 143.8 20.2 35.1 237.4 19.1 28.1 268.4 24.5 124.3 53.6 360.7 54.3 138.5 122.1 263.3 190.3 19.4 18.6 124.8 252.8 71.0 215.8 22.3 21.1 112.3 131.2 126.7 21.3 8.5 19.1 47.8 115.5 2.1 116.3 66.2 158.9 99.4 96.5 343.5 19.9 356.6 45.4 19.4 21.0 142.6 103.4 181.3 119.7 107.0 174.3 17.7 0.0 0.0 0.4 0.6 509.6 78.9 0.4 187.7 303.5 294.9 441.2 0.0 0.1 0.2 1.9 501.8 0.0 0.1 0.8 0.2 97.1 187.2 2.4 0.0 0.0 0.0 172.8 0.4 0.9 1293.8 0.0 63.8 0.1 0.0 0.2 0.1 0.1 0.0 1.0 0.4 0.7 0.6 32.2 0.0 0.6 0.8 0.3 224.3 0.2 0.0 0.6 0.6 0.3 0.7 0.0 63.6 272.2 0.4 0.4 0.4 0.5 205.0 0.2 0.2 0.1 0.1 0.6 0.3 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 20.2 19.1 28.1 19.4 18.6 22.3 21.1 19.1 19.9 21.0 17.7 347.2 0.0 1.1 1.3 1.4 76.3 0.3 0.0 9.6 1.5 8.1 14.0 25.0 10.0 0.6 5.5 0.0 0.3 2.1 0.0 172.1 0.8 2.2 1.7 46.8 134.1 0.0 0.0 0.6 20.5 0.3 566.4 1.5 1.0 0.0 0.4 55.6 2.5 2.6 0.0 6.6 3.9 0.0 191.8 110.1 3.7 70.2 27.9 135.2 74.0 0.0 1.9 0.0 12.1 0.1 3.0 0.0 8.6 1.0 1.0 0.1 25.5 0.0 0.8 85.5 43.7 146.1 1.8 5.9 6.3 62.7 0.7 9.6 33.2 0.5 0.5 CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 889.6;liver: 2472.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1371.0;Distal tubular cells: 2156.1;Hepatocytes: 3376.3;Proximal enterocytes: 1856.4;Proximal tubular cells: 3630.6" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1117.0;RT4: 513.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" 309.5 109.6 38.4 31.2 39.7 25.3 253.5 42.2 45.2 86.0 37.6 146.5 438.2 44.9 176.2 78.1 81.9 301.2 84.8 37.5 38.8 889.6 2472.0 356.6 43.7 43.1 39.7 223.9 461.3 236.0 58.5 81.8 41.9 95.9 103.4 10.3 59.1 122.8 41.4 118.4 381.7 46.7 40.8 75.6 194.8 57.9 40.0 51.6 42.5 42.1 35.2 155.5 68.3 43.5 78.8 130.8 67.4 0.6 1117.0 198.2 89.5 52.6 113.8 111.0 163.8 156.2 82.7 95.6 36.7 97.6 54.4 170.6 0.1 73.1 86.9 179.8 91.7 34.9 65.6 418.1 174.6 67.3 44.1 334.1 57.4 63.0 32.3 66.0 63.6 85.8 58.6 35.0 93.7 140.9 38.3 80.5 30.4 110.0 86.8 93.6 21.9 2.3 111.9 513.2 190.4 79.7 51.4 137.1 65.8 56.6 271.5 63.7 57.9 0.6 85.8 26.6 68.1 24.6 109.2 30.3 67.0 19.2 64.3 4.1 29.5 7.5 51.3 36.3 116.2 93.7 55.6 60.2 53.7 112.7 54.5 68.6 3.7 36.3 45.7 47.8 48.8 43.2 38.4 39.7 42.2 45.2 37.5 38.8 43.1 39.7 41.9 40.8 40.0 43.5 169.7 637.8 1371.0 11.4 76.0 98.0 82.1 368.6 50.7 9.9 345.8 213.2 90.7 836.4 1053.2 842.4 4.2 229.3 29.4 197.0 2156.1 239.4 7.5 163.1 76.6 119.9 164.2 180.0 13.1 504.6 169.8 141.4 208.9 345.6 39.9 55.0 177.4 3376.3 97.4 8.4 12.6 236.5 457.7 128.6 72.9 26.7 158.1 60.8 90.7 10.3 224.1 39.2 32.0 14.1 22.7 266.7 358.9 149.7 33.4 142.0 1856.4 3630.6 619.5 14.0 52.6 49.6 85.0 15.3 42.0 141.2 223.9 44.5 52.6 1123.6 329.9 220.7 CYB5D2 MGC32124 ENSG00000167740 "Cytochrome b5 domain containing 2" Q8WUJ1 17 4143168-4187310 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 130.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 74.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011032, HPA042299" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum, Plasma membrane" "HPA011032: , HPA042299: AB_10793879" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (4.16e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.88e-2)" "unprognostic (1.75e-2)" "prognostic favorable (4.98e-6)" "unprognostic (1.57e-1)" "unprognostic (2.47e-1)" "unprognostic (9.71e-3)" "prognostic favorable (7.76e-5)" "unprognostic (2.04e-1)" "prognostic favorable (2.03e-10)" "unprognostic (2.01e-3)" "unprognostic (8.73e-2)" "unprognostic (1.82e-1)" "unprognostic (2.97e-1)" 19.0 21.7 17.4 6.1 17.3 4.3 18.2 17.4 20.1 15.9 14.2 10.7 15.2 15.6 28.5 10.9 18.7 16.3 14.0 16.7 19.6 25.5 29.0 9.7 9.3 18.1 17.6 20.8 19.7 30.9 24.1 10.8 17.8 13.5 7.4 9.2 20.0 17.6 16.2 14.4 12.1 8.4 17.6 9.6 16.0 29.3 17.9 10.2 22.7 14.9 7.2 12.9 11.7 18.7 16.2 21.6 11.8 12.7 74.7 22.5 5.2 15.7 31.5 11.0 10.9 6.3 10.3 5.3 13.6 17.4 9.2 22.5 4.9 7.1 4.4 17.9 25.7 5.0 13.5 10.5 13.7 2.1 9.5 28.8 17.0 6.2 11.7 22.3 20.1 11.5 5.1 31.2 8.3 20.6 7.8 3.4 4.3 13.7 11.5 9.2 10.6 12.5 25.1 8.5 9.3 8.1 17.2 9.9 23.5 13.1 25.6 3.2 28.5 15.7 4.0 14.5 8.0 5.8 4.9 3.9 19.9 4.5 6.2 0.6 10.8 13.6 5.9 9.2 6.7 8.1 9.3 7.4 10.5 7.1 8.6 8.0 9.5 5.5 8.7 11.3 11.2 8.2 17.4 17.3 17.4 20.1 16.7 19.6 18.1 17.6 17.8 17.6 17.9 18.7 57.4 12.8 10.3 9.1 17.2 53.7 18.4 36.0 12.5 26.9 35.4 36.7 9.8 45.8 21.8 31.3 58.4 55.7 11.4 18.5 52.8 34.3 28.5 36.6 20.0 34.4 13.8 33.3 7.6 27.0 29.1 23.8 19.4 23.4 11.4 22.3 41.0 32.9 21.4 40.4 10.4 16.0 36.7 24.0 23.8 30.6 28.9 17.3 14.2 4.7 15.4 37.6 15.5 8.5 10.0 26.9 18.9 28.6 17.6 8.3 39.7 55.7 38.5 30.4 0.0 15.2 20.1 130.3 29.2 9.5 42.9 38.6 15.8 39.3 16.6 15.8 CYB5R3 DIA1 ENSG00000100243 "Cytochrome b5 reductase 3" P00387 22 42617840-42649392 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 830.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001566 Approved Supported "Endoplasmic reticulum" NA NA 1500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "HPA001566: AB_1078601" "unprognostic (4.73e-2)" "unprognostic (2.93e-1)" "unprognostic (1.79e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.45e-1)" "unprognostic (8.22e-3)" "unprognostic (3.01e-1)" "unprognostic (2.72e-2)" "unprognostic (6.76e-2)" "unprognostic (3.33e-3)" "unprognostic (1.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-1)" "unprognostic (5.24e-2)" 404.4 310.5 147.1 87.4 152.9 82.7 272.2 145.7 189.9 237.3 115.0 192.4 94.8 248.4 58.8 152.4 174.0 139.5 374.3 138.7 163.9 182.9 279.4 201.3 76.3 194.7 174.2 218.3 89.1 62.0 137.4 107.8 169.9 181.4 74.9 27.3 149.8 239.3 203.0 233.6 138.1 200.2 154.8 101.4 182.0 142.7 156.7 54.0 157.8 140.5 72.3 216.7 210.0 160.2 125.5 78.6 126.6 78.6 830.9 654.7 74.4 359.2 330.0 262.2 232.4 104.0 95.6 58.8 156.6 668.8 113.8 112.4 85.3 178.0 133.7 63.9 187.3 83.6 127.3 202.4 211.0 118.4 149.5 397.4 138.1 188.9 124.5 190.8 220.0 74.0 73.5 296.3 361.9 137.9 116.8 108.4 51.0 129.2 142.7 84.9 153.8 131.3 202.0 90.6 56.1 73.2 118.6 113.2 134.0 92.6 90.6 112.0 340.9 282.0 175.3 192.3 137.9 78.3 91.2 72.4 328.8 67.8 237.9 126.3 104.0 300.3 75.9 135.3 76.6 110.1 72.8 83.9 154.0 102.7 50.8 54.0 53.8 63.5 176.7 140.8 95.0 86.4 147.1 152.9 145.7 189.9 138.7 163.9 194.7 174.2 169.9 154.8 156.7 160.2 238.5 86.6 62.2 17.0 51.7 110.1 95.5 184.8 27.3 16.7 52.3 73.2 106.4 105.8 100.9 60.7 4.2 110.0 37.0 90.5 49.0 216.4 4.8 51.4 82.9 161.5 83.7 113.9 12.3 107.0 199.3 183.4 38.2 65.4 62.8 57.8 180.2 230.4 108.3 16.8 16.1 45.8 142.4 50.6 112.0 17.0 253.9 67.7 176.1 25.3 112.5 91.0 33.0 7.1 26.4 156.8 85.6 280.6 36.7 82.3 116.9 110.8 53.3 18.4 190.7 62.5 202.5 23.8 45.5 57.5 112.7 117.9 43.0 233.1 55.2 96.4 CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 221.2;Fibroblasts: 243.4;Leydig cells: 202.0;Peritubular cells: 221.5;Proximal enterocytes: 689.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "ASC diff: 1064.0;ASC TERT1: 453.8;BJ hTERT+: 408.2;HSkMC: 327.3;hTERT-RPE1: 276.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" 166.7 97.5 32.6 24.4 38.8 18.3 148.7 33.9 34.1 140.0 32.6 68.7 197.7 100.2 49.7 70.6 88.2 153.7 128.6 28.2 45.9 32.0 21.7 129.9 33.8 45.2 38.7 180.9 21.6 12.0 26.1 38.1 40.5 70.6 39.0 22.2 63.7 76.7 23.3 85.0 233.4 87.9 35.6 30.6 53.3 23.8 35.9 27.9 231.0 82.8 30.1 84.3 90.4 43.0 24.8 18.1 10.1 19.2 1064.0 453.8 1.3 88.3 408.2 45.0 56.4 1.1 33.8 0.0 14.8 214.2 46.2 12.2 8.4 7.2 53.2 18.9 2.2 20.7 26.1 0.4 222.7 22.0 1.9 327.3 68.8 70.5 13.7 276.3 29.6 12.4 7.0 0.2 128.3 0.0 7.1 20.4 5.1 0.0 4.6 2.5 125.3 1.5 7.0 1.4 1.3 4.7 104.2 0.2 56.5 3.6 35.8 13.5 59.5 101.0 14.4 96.1 38.3 0.3 0.4 0.2 49.5 18.3 55.6 0.0 17.4 0.8 1.6 17.7 0.3 0.0 0.3 0.2 16.8 0.0 0.0 0.0 9.8 3.6 13.7 0.7 0.0 7.5 32.6 38.8 33.9 34.1 28.2 45.9 45.2 38.7 40.5 35.6 35.9 43.0 37.6 221.2 109.0 45.1 0.9 121.2 47.3 20.3 38.7 0.0 54.7 48.0 18.4 37.1 34.7 25.8 0.0 1.9 3.4 16.1 0.0 1.0 1.5 4.2 35.6 33.9 0.0 85.0 0.9 6.4 2.3 243.4 13.3 8.3 2.5 1.6 73.5 2.4 48.5 0.0 1.5 22.2 2.0 60.7 92.0 6.1 202.0 28.4 44.4 36.5 29.3 27.9 4.1 12.1 54.2 1.8 16.2 221.5 2.2 22.5 689.4 0.3 6.9 1.5 19.7 89.6 49.9 1.2 1.2 7.0 60.1 1.4 5.9 2.8 27.6 18.2 CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338601 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 124.4" "Cell type enriched" "Detected in some" 10 "Syncytiotrophoblasts: 2007.5" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Group enriched" "Detected in many" 4 "amygdala: 4.8;hypothalamus: 4.1;medulla oblongata: 1.4;midbrain: 2.0;thalamus: 3.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 92.8;HDLM-2: 17.5;HSkMC: 31.4;SuSa: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000355, HPA051194" Enhanced Uncertain Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "CAB000355: , HPA051194: AB_2681381" "unprognostic (9.41e-2)" "unprognostic (7.44e-2)" "unprognostic (9.52e-5)" "unprognostic (6.81e-2)" "unprognostic (2.72e-1)" "unprognostic (4.25e-4)" "unprognostic (5.18e-5)" "unprognostic (1.54e-3)" "unprognostic (2.38e-2)" "unprognostic (2.52e-1)" "unprognostic (1.97e-1)" "unprognostic (5.37e-2)" "unprognostic (1.54e-5)" "unprognostic (2.52e-3)" "unprognostic (2.11e-1)" "unprognostic (1.40e-2)" "unprognostic (1.11e-1)" 8.3 9.0 4.8 0.4 0.6 0.2 2.1 0.1 0.5 0.6 0.0 0.2 0.7 0.3 0.0 0.1 0.3 0.5 1.2 0.3 4.1 0.1 0.1 0.7 0.0 1.4 2.0 3.2 1.3 0.2 0.0 124.4 0.7 0.6 0.1 0.6 0.9 2.7 0.6 1.8 0.2 1.3 0.2 0.6 0.2 6.5 3.7 0.2 2.4 0.3 0.0 3.5 0.5 0.7 0.1 0.0 0.0 0.0 1.7 92.8 6.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.3 0.5 0.4 0.0 0.0 0.0 0.0 17.5 0.0 0.6 0.2 8.1 0.6 0.0 0.1 31.4 0.0 0.3 4.0 0.3 0.0 0.0 0.0 0.8 0.4 0.7 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.4 0.2 16.3 0.0 0.5 0.1 0.3 0.1 0.2 0.0 3.0 1.6 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.1 0.5 0.3 4.1 1.4 2.0 0.7 0.2 3.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 52.8 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.0 0.1 0.0 7.9 1.5 0.0 0.0 0.0 191.3 0.0 0.0 14.0 0.0 0.3 0.0 0.0 0.9 0.0 5.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.2 0.9 12.3 0.3 0.0 0.0 2007.5 0.0 22.2 0.0 0.0 CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease variant, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 170.8;Prostatic glandular cells: 747.6;Urothelial cells: 498.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "classical monocyte: 156.9" "Lineage enriched" "Detected in many" 24 "monocytes: 156.9" "Cell line enhanced" "Detected in many" "ASC diff: 128.7;ASC TERT1: 136.8;HSkMC: 551.3;hTERT-RPE1: 128.9;SiHa: 270.0;U-87 MG: 142.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 34.6" "CAB011705, HPA026863" Approved Uncertain Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB011705: AB_731810, HPA026863: AB_10600900" "unprognostic (7.25e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.68e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (9.69e-2)" "unprognostic (4.20e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.87e-3)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "prognostic unfavorable (2.76e-4)" 28.4 12.0 2.7 31.9 6.2 2.0 29.4 1.6 8.9 34.9 10.4 3.7 2.2 41.0 19.5 7.6 44.9 23.8 29.2 2.5 2.3 24.1 7.0 16.8 11.6 3.6 2.9 5.6 7.2 0.9 14.8 4.5 3.0 34.7 2.1 1.2 4.3 39.2 3.4 6.3 5.8 35.1 3.6 27.3 15.9 8.0 7.3 28.3 8.7 5.5 1.9 35.0 6.7 1.5 7.0 71.9 2.3 0.0 128.7 136.8 0.4 0.6 4.4 1.3 12.3 0.2 30.1 0.0 19.1 17.8 3.1 58.7 0.3 4.0 2.3 5.5 3.8 0.0 21.2 0.0 36.0 0.2 0.1 551.3 55.3 30.7 1.4 128.9 0.0 0.3 0.7 0.2 0.7 29.2 0.3 22.5 7.5 10.4 14.2 0.1 0.0 0.2 13.4 0.9 0.5 2.1 270.0 38.8 0.0 7.5 49.4 10.8 0.0 1.1 0.2 107.9 0.1 0.3 0.2 0.0 142.2 0.1 11.8 1.6 156.9 0.0 0.1 23.2 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.1 6.5 0.1 18.6 0.7 0.1 70.2 2.7 6.2 1.6 8.9 2.5 2.3 3.6 2.9 3.0 3.6 7.3 1.5 56.8 19.2 66.3 0.0 1.7 17.7 118.4 86.9 8.0 0.7 18.3 42.0 3.4 0.0 79.7 46.0 0.0 0.3 1.1 0.9 15.6 6.0 15.1 11.7 100.4 103.8 1.8 0.0 4.5 0.5 0.8 114.1 3.6 28.2 3.8 0.1 7.5 12.2 12.6 0.0 0.3 1.3 4.1 103.0 50.6 12.1 159.7 112.2 17.8 64.6 140.1 1.6 3.1 0.0 0.2 0.6 0.1 170.8 0.3 747.6 0.1 1.6 11.2 0.5 19.7 4.5 32.7 12.6 2.6 2.4 14.2 0.3 2.4 1.3 1.0 498.7 CYP2U1 "SPG49, SPG56" ENSG00000155016 "Cytochrome P450 family 2 subfamily U member 1" Q7Z449 4 107931549-107953461 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 84.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.2;Inhibitory neurons: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041622, HPA046754, HPA064827" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA041622: AB_2677583, HPA046754: AB_2679787, HPA064827: AB_2685362" "unprognostic (3.54e-1)" "unprognostic (2.45e-1)" "unprognostic (3.08e-1)" "unprognostic (2.84e-1)" "unprognostic (5.16e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (1.20e-3)" "unprognostic (3.19e-1)" "unprognostic (8.97e-3)" "unprognostic (5.41e-3)" "unprognostic (3.02e-1)" "prognostic favorable (2.75e-5)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.19e-1)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 7.7 6.4 6.6 4.0 8.3 0.5 4.5 7.6 7.3 5.1 10.1 5.8 3.4 6.6 3.6 3.5 7.8 5.6 7.7 6.5 8.7 5.3 5.9 5.7 6.3 9.0 7.9 9.5 2.3 10.7 4.7 2.4 8.2 9.9 3.9 5.8 3.4 8.7 3.6 2.7 4.7 10.2 8.1 7.6 3.2 3.0 8.0 84.9 3.6 7.2 4.7 4.7 3.8 9.5 4.0 1.9 5.2 9.5 28.6 13.4 0.8 16.8 25.3 10.2 15.7 0.1 2.5 10.8 1.1 10.1 7.8 0.2 8.1 6.4 15.4 3.0 2.5 2.3 3.5 0.5 11.3 3.2 0.0 15.3 5.3 4.7 3.2 20.8 4.0 12.0 0.1 5.0 8.4 2.9 11.8 0.0 5.4 0.4 4.7 6.5 6.3 0.1 3.3 6.7 10.0 7.6 4.2 7.3 18.6 4.3 3.6 1.5 10.6 6.5 0.8 9.3 6.9 21.1 21.2 3.4 5.5 0.0 7.4 0.0 0.1 0.3 0.4 0.5 0.3 0.8 0.3 0.4 0.9 1.1 0.7 0.5 0.0 0.7 2.8 1.1 0.0 0.2 6.6 8.3 7.6 7.3 6.5 8.7 9.0 7.9 8.2 8.1 8.0 9.5 5.5 3.2 3.9 18.6 12.9 1.1 4.6 2.2 15.4 4.1 2.8 5.8 6.2 1.5 2.4 9.2 4.2 0.4 10.1 1.4 0.0 0.9 13.2 6.9 6.3 5.8 3.0 1.7 30.2 2.0 0.3 12.6 3.1 6.2 4.5 2.5 8.6 7.3 2.3 1.7 34.3 1.2 0.0 6.2 3.3 9.5 17.7 4.7 19.6 5.6 3.7 9.5 1.0 20.1 12.1 0.4 0.1 17.7 4.2 1.5 9.9 3.0 8.6 3.1 0.0 20.0 8.1 1.0 4.2 2.0 1.4 0.3 3.6 5.1 3.1 0.8 CZIB "C1orf123, FLJ20580" ENSG00000162384 "CXXC motif containing zinc binding protein" Q9NWV4 1 53214099-53220634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 29.2;Cardiomyocytes: 45.8;Cytotrophoblasts: 60.7;Extravillous trophoblasts: 76.7;Fibroblasts: 22.2;Hofbauer cells: 66.5;Syncytiotrophoblasts: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043835 Uncertain Approved "Vesicles,Mitotic spindle,Cytosol" Yes No 320000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Vesicles, Mitotic spindle" "HPA043835: AB_10796797" "unprognostic (1.09e-2)" "unprognostic (5.91e-2)" "unprognostic (2.03e-2)" "unprognostic (4.55e-2)" "unprognostic (5.43e-2)" "unprognostic (1.53e-1)" "unprognostic (9.20e-3)" "unprognostic (2.27e-1)" "unprognostic (5.52e-2)" "unprognostic (9.37e-3)" "unprognostic (1.46e-1)" "unprognostic (3.05e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (6.31e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (2.43e-1)" 55.8 35.5 56.1 22.3 58.0 21.9 49.4 57.2 74.6 53.6 56.9 66.5 22.5 57.1 39.8 32.3 52.3 30.2 52.5 57.7 56.6 39.4 43.5 33.1 30.0 57.9 56.6 47.2 25.1 34.6 28.5 30.6 57.0 41.0 34.8 21.6 24.8 45.4 76.5 26.2 31.6 59.2 57.1 32.5 40.3 31.0 57.4 36.3 35.1 65.3 29.7 57.7 37.6 59.0 32.6 34.7 44.7 41.0 101.6 129.1 39.4 47.8 50.4 47.3 50.8 29.6 27.5 50.1 39.0 58.1 45.8 12.6 27.9 46.9 57.0 65.0 47.5 51.0 24.9 45.0 100.0 59.5 32.1 84.6 50.3 50.6 53.3 71.5 78.5 61.0 53.7 13.7 60.1 54.6 73.5 55.6 74.8 39.7 54.3 52.8 56.8 39.7 55.8 32.6 37.6 36.1 45.1 40.9 47.7 72.2 29.2 59.8 49.3 54.5 31.9 38.2 47.2 19.5 30.7 57.3 43.9 58.5 42.8 60.7 56.6 58.6 50.9 72.3 46.9 46.9 49.8 53.6 68.8 45.1 55.0 54.9 22.8 59.0 60.3 46.3 68.2 51.1 56.1 58.0 57.2 74.6 57.7 56.6 57.9 56.6 57.0 57.1 57.4 59.0 29.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.0 0.0 0.0 60.7 8.2 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 76.7 22.2 0.0 0.0 0.0 0.0 0.0 0.0 66.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 46.7 1.3 0.0 0.0 0.0 DCLK1 "DCAMKL1, DCDC3A, DCLK, KIAA0369" ENSG00000133083 "Doublecortin like kinase 1" O15075 13 35768652-36131382 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.0" "Group enriched" "Detected in many" 6 "Excitatory neurons: 970.6;Inhibitory neurons: 664.8" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 29.0;ASC TERT1: 27.3;fHDF/TERT166: 23.5;GAMG: 34.8;HAP1: 17.9;HSkMC: 25.5;NTERA-2: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012405, HPA015040, HPA015655" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB012405: , HPA015040: AB_2669141, HPA015655: AB_2669265" "unprognostic (2.29e-1)" "unprognostic (2.56e-1)" "unprognostic (7.45e-2)" "unprognostic (1.30e-2)" "unprognostic (1.99e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (7.72e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (1.93e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-4)" 15.5 2.5 22.0 4.0 27.5 0.0 14.2 10.2 45.3 11.8 0.0 4.2 1.1 6.0 4.1 5.4 4.6 7.2 5.5 37.1 37.8 2.8 0.1 2.4 4.2 17.9 13.2 6.1 1.2 1.1 13.7 0.1 53.0 4.1 3.8 17.3 3.4 4.0 2.1 8.4 4.1 19.1 15.7 4.5 3.6 1.3 17.5 1.6 2.8 4.6 2.2 4.3 5.9 18.7 0.0 0.4 6.8 0.0 29.0 27.3 0.0 0.2 0.4 0.2 0.2 0.0 0.1 0.0 0.0 23.5 34.8 0.0 17.9 0.3 0.0 0.0 1.0 0.0 0.8 0.0 1.1 0.0 0.0 25.5 13.0 0.6 0.4 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 37.1 0.0 0.4 0.0 2.0 0.0 1.0 0.0 7.3 4.4 0.0 0.0 2.2 10.4 0.0 0.0 0.0 0.1 6.1 7.6 1.3 0.1 0.0 0.0 2.4 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 27.5 10.2 45.3 37.1 37.8 17.9 13.2 53.0 15.7 17.5 18.7 8.0 9.6 0.6 132.2 0.1 15.2 1.3 1.8 0.0 9.4 7.8 7.0 5.8 0.0 7.9 3.7 4.2 0.0 0.0 0.0 0.0 0.1 1.5 0.7 1.7 3.8 0.0 0.0 970.6 0.0 0.0 82.6 0.5 0.3 0.0 75.5 0.4 0.0 0.1 10.1 664.8 0.0 4.1 0.3 14.7 1.6 20.8 0.7 14.2 44.0 0.0 73.8 0.0 31.2 19.1 0.2 0.0 4.1 0.3 0.6 0.0 0.6 3.1 4.2 6.6 10.8 22.0 1.3 1.4 1.0 9.7 0.0 0.8 30.1 0.0 1.7 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DCUN1D3 "DKFZp686O0290, FLJ41725, MGC48972, SCCRO3" ENSG00000188215 "Defective in cullin neddylation 1 domain containing 3" Q8IWE4 16 20854925-20900358 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 58.6;Late spermatids: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 52.2;ASC TERT1: 38.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041983, HPA043511" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "HPA041983: , HPA043511: AB_2678521" "unprognostic (9.34e-2)" "unprognostic (4.56e-2)" "unprognostic (3.47e-2)" "unprognostic (1.33e-2)" "unprognostic (4.24e-2)" "unprognostic (8.71e-2)" "unprognostic (5.90e-2)" "unprognostic (1.73e-1)" "unprognostic (1.81e-1)" "unprognostic (7.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.31e-2)" "prognostic unfavorable (5.41e-6)" "unprognostic (1.48e-1)" "unprognostic (1.17e-1)" "unprognostic (5.31e-2)" "unprognostic (2.42e-1)" 20.6 9.5 3.9 6.3 4.3 2.8 9.3 5.5 4.6 8.3 4.1 6.2 3.3 6.2 2.5 8.3 6.9 9.7 7.1 3.4 4.8 5.2 11.9 9.9 2.6 4.0 4.0 5.0 6.8 4.4 4.7 7.9 4.0 5.4 3.9 12.6 3.7 4.1 28.5 7.1 4.0 8.6 3.7 4.4 5.9 8.3 4.8 3.2 4.4 4.0 2.6 8.3 9.4 7.2 4.8 8.6 4.2 8.7 52.2 38.9 5.4 16.1 13.6 7.9 10.5 10.7 8.5 3.0 12.6 15.8 4.7 6.1 4.8 6.7 10.6 4.0 2.9 2.5 7.1 15.8 13.6 3.7 23.9 25.9 9.0 15.2 8.5 8.4 22.2 2.9 2.9 7.4 16.4 6.6 3.4 5.5 9.9 4.1 2.7 6.1 4.5 2.6 7.0 5.0 3.6 4.8 6.2 6.2 3.6 4.7 4.2 1.8 10.9 16.5 5.4 6.9 4.4 6.9 4.3 2.0 17.1 4.1 8.3 1.3 0.3 0.2 0.4 0.6 0.3 0.2 0.2 0.6 0.4 0.3 0.3 0.6 0.3 0.6 0.5 0.2 0.2 0.2 3.9 4.3 5.5 4.6 3.4 4.8 4.0 4.0 4.0 3.7 4.8 7.2 25.6 12.8 19.3 4.6 2.9 31.4 11.7 7.5 19.4 12.4 19.0 10.8 5.2 2.8 7.2 9.2 35.5 3.6 8.2 6.3 0.0 3.8 58.6 14.5 16.2 18.4 20.3 1.3 10.6 5.2 2.0 16.5 5.6 34.3 0.0 4.2 9.7 16.3 2.3 13.5 9.7 4.3 6.1 5.0 20.6 48.5 10.8 15.8 12.4 1.9 1.8 5.2 1.0 10.6 10.8 4.9 1.2 9.8 3.3 6.1 3.0 5.2 4.3 24.8 6.6 20.1 19.6 6.4 3.7 10.7 22.6 5.1 5.9 4.1 4.7 18.3 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 DEGS1 "DEGS-1, Des-1, DES1, FADS7, MLD" ENSG00000143753 "Delta 4-desaturase, sphingolipid 1" O15121 1 224175756-224193441 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skin 1: 535.6" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 246.0;Cytotrophoblasts: 281.8;Suprabasal keratinocytes: 320.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076422 Supported Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA076422: AB_2686799" "unprognostic (2.34e-2)" "unprognostic (6.91e-2)" "unprognostic (2.48e-2)" "prognostic unfavorable (7.74e-5)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.29e-5)" "unprognostic (7.70e-2)" "unprognostic (2.31e-1)" "unprognostic (3.20e-1)" "unprognostic (3.63e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (2.87e-1)" "unprognostic (1.61e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (2.53e-4)" 60.3 31.0 30.3 44.9 33.1 69.5 61.9 35.0 36.2 53.4 42.5 50.8 47.0 44.5 29.5 48.6 34.4 40.5 43.8 31.3 35.6 38.1 35.7 49.1 48.0 36.6 35.2 27.1 22.5 31.5 34.8 128.7 35.9 83.2 27.2 20.8 38.7 58.6 20.9 535.6 33.4 70.9 37.9 38.7 38.6 22.7 34.0 34.2 52.3 23.3 50.9 48.4 72.7 44.5 72.8 50.7 65.2 49.5 275.7 181.1 51.2 201.1 223.8 137.5 164.2 47.1 55.2 58.0 252.4 181.0 82.4 76.3 76.5 67.9 153.0 84.2 141.5 41.7 51.1 29.2 167.9 84.2 86.1 177.4 153.6 125.5 69.9 143.0 140.4 31.4 62.8 61.8 181.2 27.5 43.2 46.9 83.3 40.0 76.1 38.8 92.4 37.5 181.1 19.8 42.3 69.8 106.6 169.4 110.4 118.8 57.1 123.4 125.7 133.4 41.4 153.1 197.5 44.5 55.3 52.8 141.9 41.7 154.2 104.6 61.4 120.3 30.9 67.8 59.8 58.2 52.7 43.3 104.4 74.3 40.7 37.0 67.7 43.9 48.7 34.9 59.0 52.8 30.3 33.1 35.0 36.2 31.3 35.6 36.6 35.2 35.9 37.9 34.0 44.5 71.7 83.3 29.3 13.4 69.9 246.0 44.0 33.6 89.4 31.2 40.7 38.4 20.8 10.0 19.8 11.0 14.6 281.8 40.5 4.0 13.7 34.9 27.9 54.0 90.2 66.7 14.9 18.7 17.4 43.3 48.3 77.7 21.4 146.1 106.5 21.3 55.6 20.8 93.0 18.5 20.4 6.2 34.6 57.8 90.5 13.6 63.0 72.8 69.4 20.6 57.1 26.0 10.3 25.6 32.1 29.5 5.9 79.4 50.1 44.2 20.1 29.7 20.1 18.4 105.2 42.7 89.1 84.3 44.0 50.4 320.4 198.9 58.9 43.7 6.6 13.7 DEPP1 "C10orf10, DEPP, FIG, Fseg" ENSG00000165507 "DEPP1 autophagy regulator" Q9NTK1 10 44970981-44978809 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 889.5;breast: 697.2" "Cell type enhanced" "Detected in many" "Adipocytes: 192.0;Ductal cells: 146.3;Exocrine glandular cells: 113.0;Glandular and luminal cells: 87.1;Syncytiotrophoblasts: 300.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 143.2;HDLM-2: 106.7;HHSteC: 258.2;HSkMC: 201.6;HUVEC TERT2: 165.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB013687, HPA037818, HPA037819" Uncertain Supported Vesicles,Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria Vesicles "CAB013687: , HPA037818: , HPA037819: AB_2675685" "unprognostic (3.99e-2)" "unprognostic (4.69e-2)" "unprognostic (5.57e-2)" "unprognostic (3.55e-1)" "unprognostic (1.88e-2)" "unprognostic (5.66e-3)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (4.25e-1)" "unprognostic (5.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.89e-2)" "prognostic unfavorable (2.29e-6)" "unprognostic (2.30e-3)" "unprognostic (2.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.74e-1)" 889.5 48.4 62.3 19.4 71.4 4.5 697.2 59.5 71.8 153.0 50.3 145.7 16.7 168.5 16.5 65.7 334.2 68.5 260.6 55.5 71.9 95.4 131.6 508.6 63.0 175.9 72.3 297.8 349.7 23.0 85.2 76.5 93.4 82.6 12.0 28.2 119.7 22.8 165.8 165.0 94.8 68.8 101.6 32.8 104.6 19.3 87.4 25.2 200.5 52.2 47.6 177.6 139.1 90.6 30.2 0.2 0.5 0.4 143.2 69.5 7.4 0.2 10.2 0.4 1.8 1.1 11.2 0.0 1.6 13.5 7.1 1.2 1.2 9.1 0.7 106.7 4.0 0.1 0.1 11.0 258.2 0.1 0.1 201.6 0.4 0.1 1.4 24.9 165.0 0.0 0.2 63.2 0.6 0.0 0.1 1.7 0.2 0.6 0.9 5.1 1.7 25.7 0.5 10.9 5.6 0.3 0.0 1.3 5.8 17.0 0.2 7.0 1.6 7.8 5.6 0.5 7.3 1.7 2.8 0.4 44.2 2.6 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.4 62.3 71.4 59.5 71.8 55.5 71.9 175.9 72.3 93.4 101.6 87.4 90.6 192.0 0.0 24.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 47.0 27.8 0.0 0.0 6.2 31.3 0.0 53.8 1.4 0.0 37.2 146.3 0.0 61.3 33.2 60.0 0.0 0.0 0.0 113.0 14.7 79.3 0.0 87.1 0.0 8.4 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 65.0 0.0 0.0 0.5 0.0 0.0 25.5 5.8 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 300.2 1.8 0.8 0.0 0.0 DIRAS3 "ARHI, NOEY2" ENSG00000162595 "DIRAS family GTPase 3" O95661 1 68045886-68051631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 143.9;ovary: 60.1;pituitary gland: 52.5" "Group enriched" "Detected in many" 5 "Distal tubular cells: 64.6;Theca cells: 206.2" "Group enriched" "Detected in many" 4 "endometrial cancer: 4.3;glioma: 16.3;pancreatic cancer: 5.6;thyroid cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 8.2;HSkMC: 17.2;TIME: 11.2;U-251 MG: 9.1;U-87 MG: 16.9" "Low region specificity" "Detected in all" "HPA028483, HPA028557, HPA029384" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nuclear membrane, Cytosol" "HPA028483: AB_10599599, HPA028557: AB_10602091, HPA029384: AB_10601343" "prognostic favorable (9.21e-4)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (1.69e-2)" "unprognostic (1.15e-2)" "unprognostic (2.84e-1)" "unprognostic (1.58e-1)" "unprognostic (2.31e-2)" "unprognostic (1.13e-1)" "unprognostic (7.86e-2)" "unprognostic (8.35e-2)" "unprognostic (4.33e-1)" "prognostic favorable (9.21e-4)" "unprognostic (1.34e-1)" "unprognostic (4.99e-1)" "unprognostic (1.24e-2)" "unprognostic (5.07e-3)" 1.4 20.1 25.3 0.5 18.7 0.1 5.0 2.2 11.5 5.2 3.0 3.3 7.5 2.5 10.6 1.7 3.3 10.2 11.3 7.0 143.9 6.9 9.5 5.1 0.2 39.6 49.2 60.1 20.0 7.5 52.5 0.6 18.5 2.9 0.8 4.0 2.3 2.6 1.1 2.1 1.4 1.2 7.8 2.5 4.2 5.5 104.7 1.6 3.8 1.9 0.3 3.1 6.4 8.0 0.0 1.5 1.6 0.0 5.2 3.9 0.6 4.6 1.6 0.3 1.2 0.0 0.8 0.0 0.2 4.8 0.1 0.2 0.2 0.0 0.3 0.0 0.2 0.0 0.6 0.0 8.2 0.0 0.0 17.2 0.1 0.7 0.0 0.0 1.0 0.2 0.3 0.0 5.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.2 0.0 0.1 0.5 0.1 0.0 11.2 0.0 0.5 0.2 9.1 2.7 0.0 0.0 16.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 25.3 18.7 2.2 11.5 7.0 143.9 39.6 49.2 18.5 7.8 104.7 8.0 0.3 0.0 1.8 5.2 0.0 3.2 25.0 0.6 0.6 1.1 5.4 6.5 5.9 7.2 2.5 3.7 10.4 1.1 0.0 0.4 64.6 3.7 0.1 0.7 0.7 1.7 16.2 0.0 2.2 18.7 0.1 10.3 4.1 1.8 0.0 0.8 3.3 3.9 0.1 0.0 8.8 2.3 0.0 0.0 4.8 0.8 6.8 0.3 5.4 0.0 0.0 0.7 1.0 5.0 0.2 2.9 0.1 1.5 0.0 5.3 0.1 11.1 0.9 6.1 0.0 16.9 1.7 0.0 1.4 1.7 2.8 0.4 0.7 206.2 0.7 2.4 DNAH1 "DNAHC1, HDHC7, HL-11, HL11, XLHSRF-1" ENSG00000114841 "Dynein axonemal heavy chain 1" Q9P2D7 3 52316319-52400491 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 21.5;Respiratory ciliated cells: 35.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.6" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "midbrain: 3.4" "HPA036805, HPA036806" Uncertain NA NA "Cluster 40: Neutrophils - Inflammatory response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "HPA036805: AB_10670924, HPA036806: AB_10670849" "unprognostic (8.34e-3)" "unprognostic (3.60e-2)" "unprognostic (9.60e-4)" "unprognostic (1.54e-2)" "unprognostic (2.99e-1)" "unprognostic (6.59e-4)" "unprognostic (1.62e-1)" "unprognostic (1.43e-2)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "unprognostic (4.79e-2)" "unprognostic (4.98e-4)" "unprognostic (1.84e-3)" "unprognostic (8.66e-3)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (9.80e-5)" 2.1 1.4 0.2 2.1 0.7 6.2 1.7 0.0 1.1 1.4 2.1 1.4 1.3 1.5 1.3 1.3 4.0 1.6 1.0 0.3 0.5 1.5 2.4 2.4 3.1 1.3 1.7 1.9 1.5 1.4 1.8 1.0 0.8 1.6 1.3 2.5 1.5 0.7 1.1 1.7 2.9 1.7 0.3 2.9 1.6 4.1 0.6 1.9 1.5 0.5 2.4 1.1 1.1 1.8 0.1 0.7 1.0 1.0 1.2 4.6 0.5 0.6 1.0 0.2 0.2 0.0 0.6 0.3 0.6 0.8 0.1 0.1 0.0 0.2 0.4 0.8 1.4 2.0 0.1 0.2 0.6 1.5 1.3 2.0 0.3 0.8 1.0 2.1 0.8 0.8 0.2 1.7 0.8 0.2 0.4 1.4 0.5 0.1 0.9 0.7 0.0 0.6 0.3 0.8 0.1 0.5 1.0 0.1 0.7 0.3 0.2 2.4 1.0 0.3 0.2 0.9 0.2 1.8 1.8 0.5 0.3 1.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 1.1 0.3 0.5 1.3 1.7 0.8 0.3 0.6 1.8 2.2 6.4 3.7 9.1 3.2 0.5 0.4 2.0 0.6 1.8 1.7 1.8 4.4 0.0 2.7 0.0 4.2 0.6 3.1 2.3 0.0 0.3 9.7 6.9 1.6 2.1 5.4 2.7 13.8 0.6 0.2 1.2 8.2 3.8 3.8 3.2 2.2 3.9 1.2 5.0 10.0 2.6 8.2 3.5 1.6 21.5 1.2 3.2 1.8 3.7 3.4 0.9 4.1 2.5 10.7 0.3 2.1 0.4 2.4 0.9 4.8 0.9 35.5 5.2 0.0 1.4 1.9 6.9 1.5 1.1 0.3 0.8 3.3 1.7 2.2 0.6 DNAJC28 "C21orf55, C21orf78" ENSG00000177692 "DnaJ heat shock protein family (Hsp40) member C28" Q9NX36 21 33485530-33491716 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 14.0;Early spermatids: 33.3;Proximal tubular cells: 10.4;Spermatocytes: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018003, HPA030076" Approved NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA018003: AB_1845695, HPA030076: AB_10602218" "unprognostic (9.63e-3)" "unprognostic (4.44e-1)" "unprognostic (5.66e-3)" "unprognostic (2.05e-1)" "unprognostic (4.00e-2)" "unprognostic (4.92e-3)" "unprognostic (2.89e-2)" "unprognostic (6.61e-3)" "unprognostic (1.45e-1)" "unprognostic (7.23e-4)" "unprognostic (1.20e-3)" "unprognostic (1.04e-1)" "unprognostic (3.14e-9)" "unprognostic (1.84e-1)" "unprognostic (1.71e-1)" "unprognostic (4.53e-2)" "unprognostic (1.24e-2)" 0.6 2.2 0.8 0.1 0.8 0.4 0.7 0.9 1.2 0.5 0.7 1.1 0.3 0.5 1.2 1.1 0.3 0.5 2.9 0.8 0.7 2.6 2.6 0.6 0.2 0.8 0.7 0.4 1.3 1.4 1.5 0.5 0.8 0.8 0.7 1.7 1.4 0.6 2.8 0.6 1.1 0.3 0.5 1.2 1.5 7.0 0.8 0.1 2.5 2.0 0.1 0.7 0.6 0.9 0.3 0.1 1.2 0.4 3.1 0.8 0.3 0.6 0.6 1.2 0.5 0.1 0.5 0.3 0.1 0.0 0.6 0.1 0.1 0.1 0.3 0.1 1.3 0.7 0.2 0.8 0.7 0.0 1.2 0.6 0.6 0.6 0.1 1.0 0.7 0.6 0.4 0.1 0.4 0.4 0.1 0.3 0.6 0.4 0.0 0.3 1.3 0.1 0.6 0.1 0.9 0.6 0.1 0.0 0.3 0.4 1.1 0.2 0.2 0.5 0.2 0.1 0.1 0.5 0.5 0.1 1.1 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.8 0.8 0.9 1.2 0.8 0.7 0.8 0.7 0.8 0.5 0.8 0.9 1.3 0.0 2.2 0.3 0.7 0.4 0.3 1.1 1.8 1.7 1.2 0.9 14.0 1.5 0.5 3.7 0.0 1.3 0.9 1.3 3.9 2.2 33.3 0.7 0.8 1.4 1.2 4.0 2.5 1.3 0.4 1.1 1.1 0.9 3.8 0.8 1.4 4.7 1.0 1.7 2.3 1.1 0.0 2.4 0.3 7.6 0.6 0.9 0.0 1.9 1.3 0.9 0.0 1.0 1.2 1.7 1.2 1.2 2.0 0.6 1.8 10.4 2.4 2.2 0.0 1.1 1.2 13.4 2.0 0.6 0.0 2.3 0.8 3.0 0.6 0.2 DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 5 "Fibroblasts: 457.5;Leydig cells: 231.8;Peritubular cells: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 143.3;fHDF/TERT166: 59.9" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" 334.6 39.6 0.4 28.6 0.5 0.0 251.3 0.5 1.0 177.6 0.5 424.7 18.8 63.2 60.8 86.0 129.1 78.0 241.4 0.5 0.4 13.2 29.0 48.6 58.6 0.5 0.4 30.3 84.8 4.9 2.1 37.5 0.6 55.2 58.2 0.0 72.0 52.7 37.1 39.2 94.2 138.5 0.5 0.9 108.5 15.4 0.5 48.0 75.0 209.3 70.1 103.3 166.9 0.7 0.0 0.0 0.0 0.0 143.3 0.6 0.2 0.1 6.7 7.2 7.4 0.0 0.0 0.0 0.0 59.9 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 4.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.6 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.5 1.0 0.5 0.4 0.5 0.4 0.6 0.5 0.5 0.7 18.7 3.2 1.7 0.3 0.3 31.9 0.1 0.0 1.8 0.0 2.2 2.3 7.4 0.0 0.6 0.0 0.0 0.6 0.4 0.1 0.0 0.1 1.2 0.3 10.7 6.9 0.0 0.0 4.8 0.2 0.8 457.5 3.1 0.2 0.0 0.0 8.9 0.0 0.6 0.0 3.4 0.0 0.0 0.0 45.6 4.4 231.8 4.0 39.2 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 123.8 0.5 0.5 0.0 0.1 0.0 0.0 0.0 24.4 18.5 0.5 0.3 3.1 32.0 0.4 5.0 2.2 0.0 0.6 DPY19L3 ENSG00000178904 "Dpy-19 like C-mannosyltransferase 3" Q6ZPD9 19 32405543-32485895 "Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 71.5;Horizontal cells: 79.1;Oligodendrocyte precursor cells: 97.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008325 Approved Approved Microtubules NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" Microtubules "HPA008325: AB_1847853" "unprognostic (9.58e-3)" "unprognostic (3.89e-1)" "unprognostic (2.24e-1)" "unprognostic (3.60e-1)" "unprognostic (5.21e-2)" "prognostic favorable (5.55e-4)" "unprognostic (2.00e-2)" "unprognostic (3.76e-2)" "unprognostic (1.28e-3)" "unprognostic (3.27e-1)" "prognostic favorable (1.70e-4)" "unprognostic (3.26e-1)" "unprognostic (1.02e-2)" "unprognostic (6.34e-2)" "unprognostic (1.87e-1)" "unprognostic (1.75e-1)" "unprognostic (9.72e-3)" 5.9 7.3 10.9 5.2 12.6 8.9 6.9 12.1 11.2 8.1 13.5 4.4 2.9 7.2 6.1 4.2 6.0 6.9 3.6 14.4 13.1 5.7 5.2 5.3 4.7 10.7 11.4 13.0 5.0 8.2 6.4 8.3 9.9 10.8 4.6 9.2 7.9 5.6 1.9 3.0 4.2 5.3 8.7 6.6 6.8 8.9 10.5 5.6 10.4 3.0 4.6 5.3 3.5 10.5 4.6 8.7 32.9 15.0 32.9 16.8 16.4 14.2 10.1 5.8 10.5 10.5 5.4 18.6 8.7 10.5 4.2 2.4 13.8 6.5 11.2 9.1 8.6 24.5 9.1 9.6 21.6 13.0 13.9 17.6 3.4 7.1 6.9 11.0 13.9 8.6 17.7 5.9 15.1 7.8 3.4 6.4 13.7 9.0 3.5 9.1 13.1 5.7 10.9 11.4 7.3 19.4 7.0 6.7 7.8 18.1 5.3 15.1 15.4 11.9 8.3 7.1 15.1 8.6 19.0 12.5 16.5 15.3 19.5 5.3 1.6 5.2 1.1 1.3 0.6 1.3 1.0 1.1 1.4 1.7 0.8 0.9 5.8 0.9 1.9 1.0 1.6 0.6 10.9 12.6 12.1 11.2 14.4 13.1 10.7 11.4 9.9 8.7 10.5 10.5 8.1 6.4 15.1 71.5 4.8 2.0 3.8 2.7 5.2 15.2 8.3 5.5 3.3 4.3 5.2 14.7 10.4 6.8 4.7 4.3 1.9 2.4 2.1 13.0 16.6 8.4 3.6 6.1 30.1 3.9 5.5 11.9 9.2 17.1 1.3 21.1 20.3 5.8 5.8 79.1 35.6 8.9 6.1 19.5 3.4 2.7 10.8 4.7 1.8 25.3 4.1 22.1 9.2 97.5 24.8 2.6 5.4 11.7 6.4 11.9 5.5 3.0 6.5 13.3 0.0 12.5 6.7 11.5 18.7 4.5 3.0 14.9 2.9 11.5 3.5 3.5 DTWD1 "MDS009, MGC111207" ENSG00000104047 "DTW domain containing 1" Q8N5C7 15 49621037-49656232 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042214 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Vesicles" Yes No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Vesicles" "HPA042214: AB_2677903" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (3.00e-1)" "unprognostic (3.70e-4)" "unprognostic (8.12e-2)" "unprognostic (2.37e-1)" "unprognostic (1.82e-1)" "unprognostic (9.87e-2)" "unprognostic (4.44e-3)" "unprognostic (4.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-3)" "unprognostic (1.02e-1)" "unprognostic (7.85e-2)" "unprognostic (2.80e-2)" "unprognostic (2.35e-1)" 19.6 11.8 7.7 13.0 10.1 5.4 18.2 8.2 9.1 27.4 6.5 21.1 7.4 22.6 16.8 13.3 21.1 23.0 11.0 9.0 8.9 11.0 11.5 10.9 12.9 5.7 6.9 22.7 33.3 11.5 9.2 12.8 6.0 15.7 11.9 8.8 21.5 14.7 10.3 12.2 9.1 20.5 6.4 9.0 14.9 9.5 9.9 11.7 17.6 21.1 10.0 20.4 15.9 9.8 10.0 11.9 21.2 11.5 41.3 84.1 16.6 29.3 28.6 36.8 27.5 4.2 8.3 16.7 20.3 38.7 16.8 17.8 15.6 15.8 37.7 10.8 11.2 13.8 23.5 14.5 29.1 18.0 11.1 38.8 20.4 24.3 29.7 32.9 15.5 19.3 26.3 17.3 41.7 23.3 12.3 15.1 12.4 22.6 15.7 17.4 44.7 64.9 12.3 7.1 18.6 14.4 34.7 11.5 27.3 22.1 12.1 25.4 10.7 43.6 17.3 25.6 32.3 13.2 22.2 10.0 37.5 53.9 28.3 8.7 9.7 5.2 6.8 11.7 9.8 9.7 10.3 11.6 12.8 10.1 12.0 11.5 2.6 13.9 15.3 25.3 8.9 6.0 7.7 10.1 8.2 9.1 9.0 8.9 5.7 6.9 6.0 6.4 9.9 9.8 39.9 19.2 15.0 36.6 16.6 19.2 15.4 31.9 18.2 41.8 23.0 34.0 18.8 12.8 22.1 35.0 31.3 23.4 27.1 4.7 31.3 20.1 21.0 27.8 88.1 23.6 15.5 20.8 57.2 21.0 27.7 49.9 20.4 14.1 7.0 29.3 25.4 14.9 19.5 18.5 55.2 19.2 40.7 16.4 14.9 11.2 37.9 16.7 16.0 18.7 10.4 20.3 18.6 33.7 66.1 20.8 10.3 28.2 27.0 21.5 9.5 22.0 37.9 40.0 6.6 35.5 46.7 51.2 44.3 19.6 19.0 9.7 16.2 35.4 17.1 12.7 EBF2 "COE2, FLJ11500" ENSG00000221818 "EBF transcription factor 2" Q9HAK2 8 25841725-26045413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.8" "Cell type enhanced" "Detected in some" "Adipocytes: 11.9;Fibroblasts: 23.2;Microglial cells: 13.1;Sertoli cells: 39.5;Smooth muscle cells: 53.4" "Cancer enhanced" "Detected in many" "renal cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 22.7;ASC TERT1: 45.7;HSkMC: 46.9;hTEC/SVTERT24-B: 26.7;U-138 MG: 17.1;U-2197: 22.7;U-87 MG: 19.1" "Group enriched" "Detected in many" 4 "basal ganglia: 5.7;cerebellum: 3.1;hypothalamus: 2.0;midbrain: 4.4;pons and medulla: 2.8" "Region enriched" "Detected in many" 5 "spinal cord: 8.7" "HPA003954, HPA055101" Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA003954: , HPA055101: " "unprognostic (3.70e-1)" "unprognostic (3.88e-3)" "unprognostic (2.69e-2)" "unprognostic (2.47e-3)" "unprognostic (1.03e-1)" "unprognostic (6.10e-2)" "unprognostic (5.92e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-2)" "unprognostic (6.13e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (7.41e-4)" "unprognostic (2.28e-1)" "unprognostic (3.80e-2)" "unprognostic (1.82e-2)" 17.8 0.7 0.2 0.9 0.5 0.0 8.0 0.2 0.1 0.7 0.1 1.4 0.0 0.8 1.9 0.8 4.0 2.6 9.8 0.0 0.7 0.5 0.0 0.6 0.6 1.3 3.1 1.0 0.8 2.2 0.4 0.5 2.7 0.5 0.4 0.2 1.4 0.4 4.7 1.5 0.7 1.7 3.8 0.0 0.8 1.1 0.9 1.4 6.2 9.6 0.2 1.9 1.2 0.3 0.0 0.0 0.8 0.0 22.7 45.7 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 46.9 0.0 26.7 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 17.1 0.2 22.7 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.1 0.0 0.7 1.3 3.1 2.7 3.8 0.9 0.3 11.9 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.6 0.1 0.2 0.3 5.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.1 5.6 0.0 0.0 0.5 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.4 3.2 5.9 0.6 0.0 13.1 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 39.5 2.6 53.4 1.0 0.2 0.4 0.3 0.0 0.2 0.1 0.0 0.1 EDA2R "EDA-A2R, EDAA2R, TNFRSF27, XEDAR" ENSG00000131080 "Ectodysplasin A2 receptor" Q9HAV5 X 66595637-66639298 "Predicted membrane proteins" Differentiation "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 8.3;Microglial cells: 5.6;Oligodendrocytes: 6.4;Theca cells: 5.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 24.3;HSkMC: 33.3;LHCN-M2: 31.8;SuSa: 25.2" "Not detected" "Not detected" HPA054522 Approved "Cell Junctions" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "Cell Junctions" "HPA054522: AB_2682516" "unprognostic (1.31e-3)" "unprognostic (3.17e-3)" "unprognostic (2.19e-1)" "unprognostic (8.49e-3)" "unprognostic (4.15e-3)" "unprognostic (3.63e-3)" "unprognostic (2.48e-2)" "unprognostic (3.37e-2)" "unprognostic (2.82e-1)" "unprognostic (7.17e-2)" "unprognostic (6.04e-2)" "unprognostic (2.74e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (8.23e-2)" "unprognostic (4.92e-2)" "unprognostic (3.08e-1)" 2.1 5.7 1.7 0.5 2.4 0.0 3.0 1.9 2.1 6.1 3.8 2.2 0.3 5.7 4.2 2.4 4.3 3.3 2.1 1.7 1.8 1.2 0.8 2.6 0.5 2.5 1.8 7.5 3.1 3.0 3.4 1.1 2.7 4.0 4.9 0.7 2.5 5.4 2.4 1.5 1.1 5.2 2.2 1.2 0.8 1.4 2.3 2.6 5.6 0.9 0.4 2.4 4.3 3.7 0.0 16.4 15.0 0.0 21.0 24.3 0.2 22.5 24.0 2.1 3.3 0.0 0.0 8.3 0.0 14.6 0.0 0.1 0.0 8.6 7.3 0.0 7.8 0.0 0.5 11.0 3.7 0.0 0.1 33.3 20.0 16.4 15.1 20.2 0.5 0.4 0.8 8.4 31.8 1.9 0.4 0.0 5.6 0.0 0.0 0.0 2.0 0.0 1.5 0.0 0.0 2.7 0.0 0.0 0.0 25.2 0.5 0.3 17.3 0.0 12.0 0.0 0.2 0.0 0.1 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.4 1.9 2.1 1.7 1.8 2.5 1.8 2.7 2.2 2.3 3.7 0.5 3.2 0.0 0.7 0.8 0.3 1.0 1.5 2.8 0.1 1.2 1.7 0.5 1.5 1.4 1.8 0.0 1.2 0.1 0.0 0.0 0.2 0.0 0.5 1.2 0.6 1.2 0.0 0.0 0.6 1.3 2.5 0.5 0.2 0.0 8.3 0.7 0.0 0.2 0.0 0.3 0.5 2.0 0.0 0.3 0.0 1.8 0.1 1.8 5.6 0.0 1.5 1.0 2.0 6.4 0.6 0.3 0.4 0.0 1.1 0.2 0.4 1.0 0.0 0.0 3.6 1.6 0.0 0.2 0.7 0.6 0.7 0.6 5.0 0.5 0.6 EDEM3 C1orf22 ENSG00000116406 "ER degradation enhancing alpha-mannosidase like protein 3" Q9BZQ6 1 184690237-184754907 "Enzymes, Predicted intracellular proteins" "Unfolded protein response" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025754, HPA025755, HPA027297" Approved Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum" "HPA025754: AB_1845638, HPA025755: AB_1845639, HPA027297: AB_2672205" "unprognostic (1.74e-1)" "unprognostic (1.64e-2)" "unprognostic (3.08e-2)" "unprognostic (2.67e-2)" "unprognostic (2.30e-1)" "unprognostic (3.10e-2)" "unprognostic (7.52e-3)" "unprognostic (1.82e-1)" "unprognostic (7.06e-2)" "unprognostic (1.66e-1)" "unprognostic (1.66e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.63e-6)" "unprognostic (4.72e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-2)" "unprognostic (2.01e-1)" 14.3 12.4 3.8 13.8 4.8 8.2 10.9 6.6 5.1 13.7 4.3 20.6 18.8 8.8 8.0 9.2 6.6 11.7 7.2 4.1 6.5 10.6 20.3 11.2 10.2 4.7 5.7 5.7 15.7 13.0 7.1 20.8 4.6 13.5 24.0 11.4 13.2 8.7 12.2 6.6 16.3 12.0 4.5 10.5 35.8 7.4 5.5 10.8 11.8 11.4 10.7 13.6 5.8 6.3 15.1 11.2 15.0 13.4 53.8 55.0 24.5 29.9 20.7 11.1 11.6 5.9 42.4 10.5 31.8 22.8 11.3 20.1 14.6 15.6 16.4 10.3 11.9 13.8 11.7 8.5 20.7 36.4 19.5 31.6 18.8 27.1 24.2 21.0 30.4 27.4 36.8 47.4 21.6 12.5 29.3 18.8 21.2 34.1 10.2 12.7 11.6 36.2 16.1 10.4 16.9 23.9 14.7 25.2 20.8 24.9 23.7 56.3 36.1 16.1 7.2 34.3 25.5 72.1 29.8 13.6 21.3 40.7 35.6 5.0 3.5 2.2 1.4 3.5 2.5 1.3 2.2 1.7 3.1 0.9 3.0 1.6 3.6 2.2 3.6 1.6 1.5 1.8 3.8 4.8 6.6 5.1 4.1 6.5 4.7 5.7 4.6 4.5 5.5 6.3 35.1 19.2 19.3 41.4 19.9 16.7 8.4 9.8 19.9 26.1 20.4 11.4 16.0 12.8 21.8 14.7 25.0 13.8 13.2 55.1 0.0 14.0 16.0 14.3 21.2 25.9 30.6 32.4 58.2 35.6 10.9 28.0 96.8 17.0 21.0 12.9 19.2 47.0 13.0 21.9 62.8 76.5 2.0 40.1 30.3 7.1 20.5 33.0 19.6 36.5 31.0 7.8 11.3 47.3 61.6 20.0 28.1 18.0 73.6 27.1 21.4 9.7 28.1 15.2 19.7 20.3 18.7 15.0 8.7 18.2 20.5 19.4 24.9 53.8 32.4 19.1 EEPD1 KIAA1706 ENSG00000122547 "Endonuclease/exonuclease/phosphatase family domain containing 1" Q7L9B9 7 36153254-36301538 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 46.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 88.0;Oligodendrocytes: 175.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 51.8;neutrophil: 46.4" "Group enriched" "Detected in many" 6 "granulocytes: 51.8;T-cells: 23.0" "Cell line enhanced" "Detected in many" "HDLM-2: 18.3;PC-3: 22.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053668 Approved "Nuclear speckles,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" Vesicles "HPA053668: AB_2682223" "unprognostic (1.30e-1)" "unprognostic (1.19e-1)" "unprognostic (1.54e-3)" "unprognostic (5.21e-3)" "unprognostic (1.14e-1)" "unprognostic (4.76e-1)" "unprognostic (1.19e-2)" "unprognostic (3.75e-2)" "unprognostic (7.89e-2)" "unprognostic (8.77e-2)" "unprognostic (7.74e-2)" "unprognostic (2.62e-1)" "unprognostic (2.82e-1)" "unprognostic (1.07e-2)" "unprognostic (6.52e-2)" "unprognostic (2.23e-2)" "unprognostic (4.59e-2)" 19.5 5.2 9.8 4.0 12.5 8.1 18.3 10.6 14.2 10.2 7.3 12.0 9.9 7.7 3.6 7.1 7.3 11.7 11.1 10.4 10.6 5.9 24.0 8.1 4.6 12.0 12.8 8.5 11.5 2.2 4.4 4.0 12.7 12.5 3.8 1.5 4.1 3.4 46.9 12.8 11.5 5.6 10.3 10.8 17.0 5.3 13.0 12.8 3.1 12.8 3.0 10.9 9.1 19.2 2.2 5.9 1.8 5.6 16.2 3.5 0.1 1.5 7.2 1.1 2.0 1.2 4.5 5.9 1.8 2.2 16.8 2.4 2.4 2.8 1.0 18.3 4.0 0.7 0.5 11.0 1.5 0.9 5.5 7.3 1.7 0.7 0.4 4.5 0.1 4.4 7.3 0.6 1.2 2.3 6.1 14.6 8.2 7.4 22.4 1.6 2.0 1.3 3.6 4.7 4.4 3.1 0.5 0.8 2.2 3.2 1.8 7.0 0.5 2.2 6.5 1.5 1.7 4.3 5.1 0.0 5.4 3.8 1.4 23.1 5.9 51.8 3.0 3.6 5.2 0.3 23.0 6.6 3.2 0.0 5.0 1.5 46.4 3.9 1.6 2.9 11.6 4.2 9.8 12.5 10.6 14.2 10.4 10.6 12.0 12.8 12.7 10.3 13.0 19.2 32.4 0.0 0.5 30.0 1.3 2.7 14.7 1.8 1.8 4.2 4.9 7.2 4.0 34.3 2.1 0.0 20.9 0.2 0.9 10.8 5.9 26.2 17.4 8.4 3.0 14.8 9.6 1.3 28.4 7.4 0.3 4.0 20.9 7.2 8.9 0.9 3.9 16.9 25.3 6.7 88.0 6.2 0.0 5.8 5.5 3.6 5.0 9.8 3.6 45.0 3.8 2.0 0.0 1.5 175.4 16.9 12.6 16.6 0.7 8.7 19.4 1.9 2.6 1.4 6.6 2.1 6.6 0.7 5.4 4.2 4.0 0.5 3.3 6.4 6.2 10.2 EIF4A2 "BM-010, DDX2B, EIF4A, EIF4F" ENSG00000156976 "Eukaryotic translation initiation factor 4A2" Q14240 3 186783205-186789897 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011690, HPA068286" Uncertain Approved Cytosol NA NA 1600000 "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB011690: AB_732123, HPA068286: AB_2685968" "unprognostic (1.49e-1)" "unprognostic (9.62e-2)" "unprognostic (3.78e-2)" "unprognostic (9.50e-3)" "unprognostic (2.82e-2)" "unprognostic (1.10e-2)" "unprognostic (4.46e-2)" "unprognostic (6.27e-2)" "unprognostic (4.32e-3)" "unprognostic (1.00e-1)" "unprognostic (6.39e-2)" "unprognostic (3.99e-2)" "unprognostic (6.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.03e-1)" "unprognostic (4.67e-2)" "unprognostic (2.62e-2)" 178.4 288.5 277.5 105.8 302.9 7.3 243.4 328.0 388.2 274.5 251.6 282.5 143.3 325.0 196.3 178.1 322.0 205.3 383.9 309.0 331.3 287.8 202.6 156.2 192.3 275.4 254.5 606.8 272.1 189.2 292.5 218.8 290.2 249.7 179.7 310.3 213.5 262.9 675.3 93.7 165.7 252.8 270.6 159.0 196.0 155.3 316.9 178.0 293.8 553.2 170.0 224.3 186.8 275.6 95.4 44.6 179.1 30.2 624.9 589.3 59.3 158.9 138.5 159.1 202.1 159.9 34.2 200.0 812.8 213.7 283.4 146.8 255.2 66.5 272.0 182.6 134.8 304.8 54.4 214.5 249.6 68.3 209.0 402.5 291.8 47.8 368.3 764.1 275.2 161.6 109.6 311.9 496.8 14.2 112.5 31.2 183.7 337.0 199.4 143.3 124.1 122.2 305.9 110.4 331.8 71.9 241.4 175.4 356.9 427.3 269.6 244.3 205.6 122.8 63.0 123.9 87.7 252.1 374.8 85.9 86.9 71.0 63.9 233.4 78.5 88.5 125.8 87.5 200.8 245.4 183.2 154.5 91.0 203.0 273.4 224.2 50.5 169.6 125.3 85.4 187.3 282.3 277.5 302.9 328.0 388.2 309.0 331.3 275.4 254.5 290.2 270.6 316.9 275.6 265.3 118.6 220.2 68.6 416.9 690.3 770.9 595.8 412.6 267.4 396.7 308.2 271.3 327.5 447.9 261.1 64.6 450.1 370.8 306.7 661.2 254.3 33.0 287.9 297.5 319.2 407.8 221.4 146.8 94.5 251.2 367.8 250.2 344.2 312.1 267.2 258.1 142.4 226.6 390.3 138.0 372.9 455.7 228.6 385.2 56.8 385.8 242.9 345.1 92.8 318.1 383.9 256.4 73.9 118.7 136.0 410.8 472.8 235.7 737.4 567.9 665.2 337.8 192.8 236.7 409.7 489.9 223.8 165.4 314.8 618.0 615.5 449.2 345.6 380.1 879.5 EIF4EBP2 ENSG00000148730 "Eukaryotic translation initiation factor 4E binding protein 2" Q13542 10 70404145-70428618 "Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019415, HPA037410, HPA061665" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Mitochondria" "CAB019415: AB_10699019, HPA037410: AB_2675461, HPA061665: AB_2684580" "unprognostic (9.57e-2)" "unprognostic (3.22e-2)" "unprognostic (2.27e-1)" "unprognostic (1.45e-2)" "unprognostic (1.05e-1)" "unprognostic (3.51e-1)" "unprognostic (3.84e-1)" "unprognostic (7.24e-2)" "unprognostic (8.24e-2)" "unprognostic (8.19e-2)" "unprognostic (2.87e-1)" "unprognostic (1.46e-1)" "prognostic favorable (6.69e-6)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (1.53e-1)" "unprognostic (4.61e-2)" 67.7 27.6 27.8 23.2 25.2 30.4 44.8 21.8 23.6 29.0 28.9 41.2 40.4 25.1 16.5 31.9 25.8 23.8 40.8 21.0 23.9 57.3 50.5 30.5 26.2 28.9 26.6 34.9 30.2 27.5 11.2 43.8 21.7 24.7 39.6 34.9 28.2 33.6 64.2 35.0 47.3 27.2 23.6 26.7 30.9 18.2 34.7 34.5 23.2 67.4 29.2 36.2 28.2 20.1 56.3 17.8 93.7 92.0 176.9 66.8 51.8 33.5 40.5 24.0 25.9 77.5 48.1 57.2 20.1 48.6 14.9 35.6 46.2 30.4 26.9 63.6 24.0 41.4 21.1 30.8 41.5 74.4 28.4 74.8 30.8 29.4 26.4 48.4 36.8 46.0 69.0 50.7 37.5 31.5 64.3 76.3 80.7 54.2 31.8 66.3 37.6 37.4 30.7 56.3 51.1 77.6 45.7 103.0 44.5 63.8 47.2 65.3 40.6 15.6 20.0 25.8 30.2 35.5 73.2 66.5 18.1 108.2 16.3 20.8 19.2 28.7 16.4 16.8 13.2 9.0 13.1 13.8 17.2 8.2 10.9 11.4 21.1 11.6 23.0 5.7 15.7 19.2 27.8 25.2 21.8 23.6 21.0 23.9 28.9 26.6 21.7 23.6 34.7 20.1 72.5 25.6 37.6 21.9 31.9 52.9 53.5 25.4 27.9 46.8 42.9 32.5 147.0 68.6 29.1 36.8 20.9 47.3 45.2 196.7 43.0 43.9 25.9 33.1 52.1 41.4 26.5 70.5 13.0 59.3 119.1 49.9 34.7 57.8 11.4 39.0 61.8 157.4 46.0 23.5 17.5 73.6 34.6 95.4 45.1 59.0 65.9 50.9 21.4 24.4 92.9 73.1 76.2 22.1 9.1 59.5 94.7 61.3 33.8 63.4 195.2 137.0 23.4 17.2 78.9 46.4 37.1 43.7 47.1 39.1 70.0 57.3 43.0 47.0 73.1 109.4 EIF4EBP3 4E-BP3 ENSG00000243056 "Eukaryotic translation initiation factor 4E binding protein 3" O60516 5 140547662-140549576 "Metabolic proteins, Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 59.2;Exocrine glandular cells: 29.0;Gastric mucus-secreting cells: 26.5;Proximal enterocytes: 43.3;Squamous epithelial cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 25.1;JURKAT: 42.3;Karpas-707: 28.9" "Low region specificity" "Detected in some" HPA045537 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "HPA045537: AB_10965796" "unprognostic (7.29e-2)" "unprognostic (4.20e-2)" "unprognostic (1.14e-1)" "unprognostic (2.44e-1)" "unprognostic (6.64e-2)" "unprognostic (4.84e-3)" "unprognostic (2.70e-1)" "unprognostic (1.24e-1)" "unprognostic (2.57e-1)" "unprognostic (8.36e-2)" "unprognostic (4.87e-3)" "unprognostic (2.17e-1)" "prognostic favorable (3.10e-4)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (8.82e-2)" "unprognostic (3.75e-1)" 43.7 66.1 23.2 6.4 24.2 12.5 45.6 24.9 29.6 27.0 25.4 38.4 12.7 21.8 6.9 36.8 36.9 17.0 42.8 22.8 25.5 41.1 55.4 26.0 12.1 25.2 23.9 30.0 49.0 2.9 17.0 7.0 25.1 41.3 17.4 2.6 54.2 15.5 121.8 49.2 39.9 8.6 25.0 31.1 59.1 32.1 23.4 12.6 35.6 55.7 9.2 30.0 28.7 25.6 0.4 1.7 1.5 2.3 18.4 19.2 3.4 1.6 0.4 0.9 1.6 3.4 1.4 0.9 8.7 3.6 1.3 1.3 0.7 1.8 1.1 3.1 5.6 0.2 3.8 6.3 25.1 10.3 4.9 23.6 2.3 1.5 1.2 4.5 2.8 42.3 0.6 28.9 1.1 0.0 7.9 18.6 2.2 5.3 6.3 8.3 1.2 0.3 2.9 3.6 9.1 1.3 2.8 23.1 7.6 2.0 3.1 11.9 2.2 7.8 1.5 5.0 1.2 2.6 2.3 0.9 5.4 20.0 2.1 9.4 43.6 1.4 11.3 51.2 14.1 41.3 20.5 10.3 37.7 37.1 41.7 34.1 22.3 24.1 38.6 117.5 17.6 24.3 23.2 24.2 24.9 29.6 22.8 25.5 25.2 23.9 25.1 25.0 23.4 25.6 0.8 0.0 13.7 0.0 8.0 0.3 0.6 0.7 59.2 0.0 6.5 3.2 0.2 7.2 4.6 0.0 0.0 0.8 1.5 13.0 3.9 8.6 1.1 4.9 0.9 2.8 8.5 11.8 0.0 29.0 0.9 8.0 26.5 1.5 12.0 0.1 2.2 7.2 2.4 0.0 0.0 15.1 0.0 5.7 0.2 1.1 1.8 9.0 0.0 0.0 7.1 0.0 1.0 0.0 0.0 14.2 19.4 0.0 0.9 0.8 43.3 7.9 7.8 0.0 0.0 0.6 1.2 2.6 0.6 42.3 0.6 1.0 3.4 0.2 18.8 0.4 ELMO2 "CED-12, CED12, ELMO-2, FLJ11656, KIAA1834" ENSG00000062598 "Engulfment and cell motility 2" Q96JJ3 20 46366050-46432985 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018811 Approved Supported Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA018811: AB_1848126" "unprognostic (1.19e-2)" "unprognostic (4.24e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.54e-4)" "unprognostic (3.71e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.08e-5)" "unprognostic (8.81e-2)" "unprognostic (3.06e-2)" "unprognostic (1.92e-1)" "prognostic favorable (6.10e-4)" "unprognostic (4.53e-1)" "unprognostic (4.42e-2)" "unprognostic (1.85e-1)" "unprognostic (1.91e-1)" "unprognostic (3.99e-2)" "unprognostic (1.20e-2)" 20.4 25.6 47.9 15.9 50.1 41.0 20.0 50.7 52.7 29.1 39.7 22.3 9.9 24.1 20.7 32.4 21.3 11.6 24.5 59.1 46.1 22.9 18.5 25.3 21.2 48.1 48.4 17.6 28.1 27.6 26.2 16.6 46.5 29.1 11.2 25.7 20.7 26.7 35.2 25.0 20.1 24.1 48.6 35.2 18.9 31.3 51.4 15.8 20.4 23.2 21.2 23.5 29.4 53.5 10.0 29.0 33.7 27.9 57.8 37.0 17.3 22.7 31.1 31.2 30.2 39.5 11.0 12.4 35.5 38.2 52.6 23.2 29.0 33.9 24.1 20.5 12.9 20.2 18.7 29.2 43.5 11.3 41.1 36.5 29.7 33.2 23.4 21.4 25.5 29.8 20.4 40.0 29.4 26.3 22.4 29.1 13.0 18.8 28.1 18.8 32.8 25.0 30.7 22.9 20.3 18.3 32.8 28.7 44.2 31.8 22.2 44.6 29.9 64.0 36.0 26.5 15.0 16.0 25.8 12.6 26.5 17.8 19.9 121.8 25.0 42.1 42.0 47.9 51.7 9.9 37.8 40.6 23.6 13.4 23.9 27.2 26.9 58.2 73.3 32.7 27.2 43.9 47.9 50.1 50.7 52.7 59.1 46.1 48.1 48.4 46.5 48.6 51.4 53.5 5.7 3.2 12.5 33.3 5.3 4.8 5.0 2.3 5.2 9.7 7.3 4.8 10.9 8.6 3.6 1.8 29.2 6.0 14.6 2.3 0.0 4.3 6.3 3.9 6.8 6.4 8.3 4.8 15.2 3.3 5.2 7.3 6.1 6.0 8.8 5.3 5.0 2.9 13.7 11.8 13.9 2.9 16.2 8.2 5.3 5.6 11.1 6.1 7.2 15.0 8.0 15.2 18.6 14.1 31.0 4.7 3.4 12.8 6.4 8.7 2.9 4.7 1.7 8.5 26.3 4.7 12.6 11.0 14.5 5.2 6.7 4.1 11.8 6.3 2.7 3.9 ELOVL3 CIG-30 ENSG00000119915 "ELOVL fatty acid elongase 3" Q9HB03 10 102226299-102229589 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 30.5" "Cell type enhanced" "Detected in some" "Adipocytes: 2.5;Breast myoepithelial cells: 3.2;Skeletal myocytes: 5.0;Spermatogonia: 3.4;Theca cells: 2.2" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "classical monocyte: 7.1;intermediate monocyte: 2.4;myeloid DC: 2.0;non-classical monocyte: 5.9" "Group enriched" "Detected in many" 10 "dendritic cells: 2.0;monocytes: 7.1" "Cell line enhanced" "Detected in many" "ASC diff: 9.5;ASC TERT1: 9.4;HSkMC: 13.9;NB-4: 11.6;SiHa: 22.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA036236 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" "HPA036236: AB_10601550" "unprognostic (1.52e-2)" "unprognostic (6.76e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (6.25e-5)" "unprognostic (8.23e-3)" "unprognostic (9.82e-2)" "unprognostic (2.17e-4)" "unprognostic (4.27e-2)" "unprognostic (2.28e-1)" "unprognostic (5.56e-2)" "unprognostic (1.84e-2)" "unprognostic (5.36e-3)" "unprognostic (2.66e-9)" "unprognostic (1.04e-1)" "unprognostic (2.81e-1)" "unprognostic (1.97e-1)" "unprognostic (1.79e-1)" 3.2 0.7 1.0 0.3 0.8 1.8 3.5 0.5 1.3 0.1 0.3 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.2 1.0 0.4 0.8 0.0 1.0 0.1 0.4 0.9 0.1 0.0 0.1 0.0 0.9 0.4 0.2 0.1 0.1 0.3 0.1 0.2 30.5 0.2 0.0 0.4 0.8 0.1 1.2 0.4 0.0 0.0 0.3 0.0 0.2 0.3 0.5 3.2 0.2 0.2 7.8 9.5 9.4 2.8 0.1 0.3 0.4 0.5 0.5 3.0 0.0 0.3 0.0 0.0 0.1 5.9 0.1 0.5 0.0 0.0 0.2 0.4 0.8 0.3 0.0 0.1 13.9 1.6 3.6 0.0 0.0 0.0 0.9 0.1 3.5 0.8 0.0 0.0 11.6 0.1 1.1 1.0 0.0 5.1 0.0 2.0 0.1 0.0 0.4 22.6 0.9 0.7 0.6 8.1 2.7 0.0 1.5 0.0 0.3 0.3 0.5 7.2 0.0 3.4 6.5 0.0 0.0 7.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.4 0.0 5.9 0.0 0.0 1.7 1.0 0.8 0.5 1.3 1.0 0.4 0.4 0.9 0.4 0.4 0.4 0.5 2.5 0.0 1.1 0.0 0.2 0.4 0.5 0.6 0.6 0.0 1.1 3.2 0.3 0.0 0.5 0.0 0.0 0.0 1.1 0.2 0.0 0.1 0.0 0.0 1.3 1.9 0.0 0.0 0.3 0.0 0.7 1.3 0.0 0.2 0.0 0.0 1.4 0.4 0.2 0.0 0.0 0.2 0.0 1.5 0.8 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 5.0 1.2 0.1 3.4 0.6 0.1 0.3 0.3 2.2 0.2 0.1 EMC3 TMEM111 ENSG00000125037 "ER membrane protein complex subunit 3" Q9P0I2 3 9962537-10011116 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 360.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042372 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "HPA042372: AB_10795609" "unprognostic (1.31e-1)" "unprognostic (2.36e-2)" "unprognostic (2.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.07e-1)" "unprognostic (8.02e-2)" "unprognostic (1.59e-3)" "unprognostic (2.90e-2)" "unprognostic (2.05e-3)" "unprognostic (2.46e-2)" "unprognostic (1.35e-1)" "unprognostic (1.91e-1)" "prognostic favorable (2.81e-6)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.71e-2)" "unprognostic (5.58e-2)" 71.1 41.1 26.5 28.9 27.6 65.7 33.3 28.5 29.9 26.1 29.7 40.6 37.4 23.2 26.9 46.1 28.9 27.9 34.3 29.2 29.4 40.3 65.7 36.1 22.7 31.0 29.5 22.5 43.6 70.5 17.2 20.3 30.4 25.8 36.0 24.2 42.8 32.0 78.5 33.6 37.3 32.0 28.3 23.1 35.3 48.5 28.8 27.2 39.9 46.7 28.5 40.7 25.1 30.4 48.9 100.7 37.4 22.5 232.6 90.3 125.1 98.1 84.6 60.1 64.8 69.5 75.6 38.7 69.8 111.9 115.2 66.7 64.2 58.3 61.7 105.2 64.3 63.6 69.9 46.5 100.4 71.8 68.2 107.4 102.5 104.9 60.1 76.5 75.6 41.8 82.0 109.2 90.2 119.5 38.3 35.6 41.5 103.2 68.7 49.0 52.4 115.7 72.8 86.7 26.4 53.1 69.9 103.3 63.4 39.1 87.5 58.0 87.6 59.8 49.6 65.0 100.8 58.3 165.6 79.0 126.2 52.0 76.4 119.7 115.1 108.5 64.5 93.6 66.8 65.6 63.7 74.5 88.3 71.2 45.8 61.5 103.5 77.3 95.3 79.1 107.3 156.1 26.5 27.6 28.5 29.9 29.2 29.4 31.0 29.5 30.4 28.3 28.8 30.4 59.1 54.5 72.9 19.9 45.3 50.6 59.9 178.0 24.5 40.6 43.0 39.9 108.1 57.2 121.4 46.0 39.6 49.5 52.7 58.6 46.9 100.6 360.7 61.6 50.2 59.2 21.1 240.2 25.4 119.9 51.8 51.1 38.7 64.0 34.1 36.5 46.1 105.0 97.8 23.5 21.1 40.2 109.9 51.0 66.6 109.3 50.4 101.7 58.7 9.4 97.5 65.2 57.7 21.1 17.8 107.4 71.3 37.6 55.6 58.7 92.6 76.9 99.1 63.5 59.2 44.7 60.7 199.7 63.0 49.6 60.7 85.8 52.7 60.6 52.0 80.2 EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2255.1;vagina: 819.5" "Cell type enhanced" "Detected in many" "Adipocytes: 835.5;Basal keratinocytes: 694.1;Endothelial cells: 662.2;Squamous epithelial cells: 888.5;Suprabasal keratinocytes: 687.6;Urothelial cells: 1193.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 1166.6;fHDF/TERT166: 861.7;HaCaT: 766.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 4.5;spinal cord: 16.0" HPA046912 Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA046912: " "unprognostic (1.40e-2)" "unprognostic (7.30e-2)" "unprognostic (8.01e-2)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (8.41e-3)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (7.46e-4)" "unprognostic (2.98e-1)" "unprognostic (4.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.45e-2)" "unprognostic (3.25e-1)" "prognostic unfavorable (9.69e-8)" 536.6 42.0 18.6 63.9 20.2 20.7 166.7 18.2 28.4 463.2 14.2 100.7 39.5 61.6 12.5 2255.1 84.8 205.8 121.8 17.7 46.5 93.9 35.1 177.9 11.4 29.5 22.9 21.8 86.8 20.6 29.9 76.9 27.2 39.6 56.4 5.5 377.8 20.3 27.0 150.9 41.8 149.2 25.1 26.2 48.5 9.2 20.8 28.4 133.5 35.6 165.4 205.7 819.5 22.1 373.5 19.4 9.1 1.9 563.2 1166.6 1.5 269.6 489.4 135.7 172.3 2.7 612.6 2.2 187.3 861.7 60.0 766.6 10.8 35.7 182.9 7.2 0.8 1.2 61.9 0.2 135.6 2.6 2.1 369.8 50.9 432.7 126.4 107.3 316.8 0.2 2.0 6.2 325.4 1.6 0.8 8.3 6.6 69.8 62.3 1.0 37.1 3.4 396.4 4.4 0.3 0.3 120.1 17.4 211.9 69.9 3.1 2.2 349.8 302.2 106.7 287.0 146.8 1.5 4.1 2.5 441.2 2.2 363.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.6 20.2 18.2 28.4 17.7 46.5 29.5 22.9 27.2 25.1 20.8 22.1 835.5 205.1 88.5 8.1 3.7 694.1 362.3 34.8 223.7 0.1 316.5 91.7 12.9 27.1 166.8 18.4 0.0 1.2 7.6 481.5 15.6 28.7 0.8 76.0 167.6 662.2 47.6 0.0 0.9 4.4 1.8 470.5 62.2 160.3 50.4 0.1 157.1 2.2 39.8 0.0 0.4 13.5 6.1 37.1 481.2 2.1 69.6 105.8 473.2 7.5 7.0 2.4 0.0 0.5 0.2 62.2 343.0 109.4 12.7 413.0 48.6 0.5 60.2 0.4 6.6 202.1 170.1 1.1 0.9 888.5 687.6 1.1 23.0 5.1 26.6 1193.8 EN1 ENSG00000163064 "Engrailed homeobox 1" Q05925 2 118842171-118847648 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.2;skeletal muscle: 13.9;skin 1: 10.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 5.6;Fibroblasts: 4.8;Melanocytes: 12.4;Skeletal myocytes: 12.0;Smooth muscle cells: 5.4" "Cancer enhanced" "Detected in many" "breast cancer: 5.6" "Region enriched" "Detected in many" 6 "midbrain: 18.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.1;ASC TERT1: 7.2;fHDF/TERT166: 13.3;HSkMC: 13.5;PC-3: 7.8;U-138 MG: 9.9;U-2197: 11.2" "Region enriched" "Detected in single" 5 "midbrain: 4.9" "Region enriched" "Detected in some" 6 "midbrain: 23.6" "CAB014884, HPA073141" Enhanced Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli rim" Nucleoplasm "CAB014884: , HPA073141: AB_2686573" "unprognostic (5.20e-2)" "unprognostic (1.61e-1)" "unprognostic (5.78e-2)" "unprognostic (4.84e-7)" "unprognostic (1.87e-3)" "unprognostic (1.90e-1)" "unprognostic (1.95e-3)" "unprognostic (1.16e-1)" "unprognostic (2.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.46e-1)" "unprognostic (3.38e-9)" "unprognostic (2.15e-2)" "unprognostic (1.88e-1)" "unprognostic (1.70e-1)" "unprognostic (9.30e-3)" 3.5 0.2 0.1 0.0 0.1 0.0 1.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.8 0.7 18.2 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 13.9 10.4 0.0 0.0 0.5 0.0 0.0 0.1 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.5 4.0 0.2 0.6 0.2 16.1 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 4.7 0.5 0.6 0.0 0.0 0.0 1.3 0.0 0.7 0.0 0.1 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.3 0.0 0.0 0.0 9.9 1.0 11.2 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.5 0.7 18.2 3.2 0.5 1.4 0.5 1.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 5.6 2.8 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 12.4 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 5.4 0.1 0.4 0.0 2.6 0.0 0.2 0.0 0.0 0.0 ENDOD1 KIAA0830 ENSG00000149218 "Endonuclease domain containing 1" O94919 11 95089846-95132645 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 99.5;Granulosa cells: 93.4;Oligodendrocytes: 122.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 194.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008932, HPA010517" Enhanced Approved "Nuclear membrane" "Secreted - unknown location" NA NA 5200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nuclear membrane" "HPA008932: AB_2262252, HPA010517: AB_1852351" "unprognostic (8.81e-3)" "unprognostic (1.92e-2)" "unprognostic (2.22e-2)" "unprognostic (1.43e-1)" "unprognostic (6.34e-2)" "unprognostic (2.78e-2)" "unprognostic (4.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.41e-1)" "unprognostic (3.65e-1)" "prognostic unfavorable (8.86e-4)" "unprognostic (2.84e-1)" "prognostic favorable (6.64e-7)" "unprognostic (5.92e-2)" "unprognostic (2.35e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (3.27e-4)" 21.9 17.3 32.6 10.7 56.4 5.8 16.7 48.0 38.5 22.2 12.8 34.7 10.8 17.6 15.1 24.7 18.5 15.8 13.1 30.3 43.2 24.3 5.9 13.9 10.2 48.2 49.9 14.6 5.7 36.3 14.9 15.9 55.8 47.5 38.6 3.4 17.1 28.3 52.3 30.1 19.4 20.8 43.4 32.5 10.3 10.3 47.4 4.0 16.2 34.7 8.8 13.6 23.4 77.9 3.7 5.8 7.0 4.3 194.4 61.9 29.3 27.2 6.0 7.2 7.4 28.3 48.8 26.4 32.7 21.7 16.0 36.0 6.9 37.3 2.8 21.3 5.2 57.4 2.6 12.1 21.3 10.7 71.0 56.3 47.6 4.1 13.3 48.5 24.9 24.8 11.8 16.7 26.8 9.9 4.5 0.4 1.6 41.2 18.2 19.5 0.0 11.1 21.0 30.6 3.7 2.9 11.5 11.4 21.2 9.6 11.6 2.9 17.9 38.6 11.3 26.1 11.7 13.8 11.0 2.2 11.7 5.6 87.8 1.2 0.8 0.6 3.6 2.2 3.4 4.6 2.3 3.1 1.9 4.7 1.9 2.3 0.4 2.2 3.9 0.8 1.5 4.2 32.6 56.4 48.0 38.5 30.3 43.2 48.2 49.9 55.8 43.4 47.4 77.9 34.1 9.6 19.4 22.9 15.6 8.0 18.9 14.9 7.4 2.4 8.4 15.9 10.9 20.0 16.2 11.0 0.0 3.6 9.9 99.5 1.9 5.5 2.7 7.1 13.8 32.4 16.2 29.9 24.9 8.9 7.8 16.9 10.2 22.9 14.5 93.4 43.2 3.9 3.1 0.0 30.2 22.2 8.2 3.4 4.9 4.4 10.2 15.6 28.4 16.9 4.3 2.2 23.7 19.1 122.9 7.9 44.5 15.1 3.3 17.7 26.9 9.2 5.8 0.8 39.5 15.9 34.5 0.4 2.5 27.8 12.5 12.4 8.8 18.5 21.0 8.8 ENPP1 "M6S1, NPPS, PC-1, PCA1, PDNP1" ENSG00000197594 "Ectonucleotide pyrophosphatase/phosphodiesterase 1" P22413 6 131808016-131895155 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins" Biomineralization Hydrolase "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 80.2;Fibroblasts: 56.9;Hepatocytes: 111.6;Peritubular cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 34.1;LHCN-M2: 21.1;U-138 MG: 27.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032904, HPA062066" Enhanced "Secreted - unknown location" NA NA 4400000 "Cluster 48: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB032904: AB_2099635, HPA062066: AB_2684674" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.60e-3)" "unprognostic (2.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.00e-1)" "unprognostic (1.60e-2)" "unprognostic (7.22e-3)" "unprognostic (8.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.00e-1)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" "unprognostic (1.96e-1)" "unprognostic (1.84e-1)" "unprognostic (3.28e-3)" 8.4 3.1 0.4 1.4 0.5 0.1 7.1 0.7 0.4 7.1 0.4 2.3 1.8 22.1 7.4 2.3 6.9 1.2 1.6 0.4 0.7 4.2 31.9 0.8 1.4 1.2 1.4 8.3 28.5 27.8 10.9 44.0 0.9 3.4 2.0 0.5 4.2 5.8 2.7 1.7 1.3 10.2 0.8 1.9 1.7 1.6 1.0 2.2 20.1 3.2 0.8 2.7 4.9 0.8 0.0 1.3 1.2 0.1 34.1 5.3 0.0 9.2 9.4 3.5 9.5 4.1 1.1 0.0 0.8 5.9 7.2 0.0 1.3 0.2 14.8 0.3 1.8 0.0 1.1 12.0 1.0 0.0 4.2 8.8 0.4 9.6 0.4 4.1 4.3 0.7 0.0 1.8 21.1 2.6 0.0 0.0 7.9 1.6 1.3 0.0 10.2 0.3 0.2 0.4 3.4 0.0 0.2 1.3 4.2 5.7 3.9 0.0 2.9 27.6 1.0 1.9 9.1 3.4 0.0 0.0 12.6 0.0 3.5 0.6 0.0 0.1 0.1 0.0 0.5 0.1 0.1 0.1 0.7 0.2 0.0 0.0 0.3 1.6 0.1 0.1 0.0 0.0 0.4 0.5 0.7 0.4 0.4 0.7 1.2 1.4 0.9 0.8 1.0 0.8 2.6 0.0 1.7 0.3 1.5 1.5 9.9 0.0 0.6 4.5 28.7 19.9 6.4 5.7 0.1 1.8 0.0 3.0 1.2 16.7 5.9 0.3 4.8 3.9 80.2 4.1 0.0 8.0 3.5 10.6 2.1 56.9 6.1 3.2 0.0 9.4 3.3 111.6 4.6 1.7 10.5 12.7 0.0 2.9 5.9 6.7 25.1 3.9 1.8 12.2 0.2 3.6 0.0 21.6 1.6 5.2 3.9 70.0 0.4 2.3 6.7 25.2 0.1 0.5 13.1 12.6 18.8 4.1 2.2 0.1 1.3 6.2 2.6 1.9 2.5 1.7 ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 383.3;choroid plexus: 753.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1041.6" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 53.8" "Lineage enriched" "Detected in many" 8 "granulocytes: 53.8" "Cell line enhanced" "Detected in many" "AF22: 111.4;ASC diff: 147.7;ASC TERT1: 312.5;BJ: 103.2;BJ hTERT+: 188.9;fHDF/TERT166: 124.2;HSkMC: 144.7;U-2197: 108.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1200000000 "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: AB_2682218" "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favorable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" 104.7 46.7 98.9 62.0 208.4 2.7 89.7 188.1 150.1 73.6 753.4 32.6 67.5 139.2 20.2 9.0 55.7 39.9 9.9 111.0 133.0 76.6 28.5 42.7 109.8 246.2 164.4 15.2 15.9 20.2 11.8 252.3 244.4 26.4 32.3 6.9 9.9 27.3 8.9 17.5 45.8 85.1 147.8 51.4 26.9 31.3 153.7 20.8 10.8 23.9 85.8 45.1 18.1 383.3 0.0 0.0 111.4 0.0 147.7 312.5 0.4 103.2 188.9 43.9 42.1 0.0 0.0 0.1 1.3 124.2 0.1 0.3 2.3 0.0 31.3 8.7 3.4 0.0 0.2 3.1 67.0 0.0 0.5 144.7 1.3 89.3 4.3 0.6 0.5 0.1 0.1 18.1 2.5 0.0 0.1 0.7 4.4 0.0 0.5 0.1 0.1 0.6 0.3 0.0 1.1 2.2 0.1 0.4 0.2 4.2 0.1 0.0 0.0 89.6 1.9 108.6 0.9 0.9 0.0 0.0 75.0 0.8 2.4 53.8 0.2 9.5 0.0 0.1 0.1 0.4 0.5 0.0 1.0 0.1 3.0 1.1 0.5 0.4 0.2 6.8 0.0 0.6 98.9 208.4 188.1 150.1 111.0 133.0 246.2 164.4 244.4 147.8 153.7 383.3 231.4 12.8 3.6 2.0 1.8 10.6 0.5 0.0 19.9 1.9 2.1 2.8 1.8 35.8 0.6 1.8 0.0 5.2 4.9 0.3 1.9 0.1 83.9 12.7 8.8 79.9 54.0 0.8 2.5 0.0 2.2 76.9 3.6 1.4 6.3 0.4 31.1 0.8 65.8 0.0 4.2 3.3 0.0 18.6 14.9 9.5 3.1 16.2 46.2 6.5 0.1 6.4 0.0 16.6 1041.6 0.7 2.6 3.4 1.9 0.1 4.2 47.6 3.7 1.2 0.0 3.1 9.6 1.7 0.4 7.8 5.3 6.4 1.7 1.1 2.8 1.4 EPHA4 "Hek8, TYRO1" ENSG00000116106 "EPH receptor A4" P54764 2 221418027-221574202 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 39.7" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 317.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 14.9" "Group enriched" "Detected in many" 6 "cerebral cortex: 23.8;hippocampal formation: 20.9" "Group enriched" "Detected in many" 9 "basophil: 1.6;gdT-cell: 1.7;MAIT T-cell: 1.7;memory B-cell: 1.3;memory CD4 T-cell: 2.5;memory CD8 T-cell: 1.7;naive B-cell: 1.2;naive CD4 T-cell: 1.0;NK-cell: 3.5;T-reg: 1.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 77.0;ASC diff: 33.9;CACO-2: 59.3;U-2197: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB028368 Enhanced NA NA 9300000 "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB028368: AB_2099353" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (2.28e-1)" "unprognostic (2.46e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (7.05e-4)" "unprognostic (1.80e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (1.12e-1)" "unprognostic (2.85e-2)" "prognostic favorable (5.67e-4)" "unprognostic (3.12e-2)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (8.66e-2)" 7.8 1.6 0.0 1.9 3.9 3.7 3.9 0.0 23.8 4.5 39.7 4.6 1.0 6.4 2.8 4.8 4.9 3.1 17.4 20.9 0.0 4.8 0.8 3.6 2.7 0.0 1.5 11.1 1.1 1.9 0.6 1.6 0.0 5.3 4.5 4.2 2.6 6.1 2.7 12.9 2.8 8.0 0.0 3.4 2.3 11.7 3.7 3.8 9.5 4.0 3.2 3.6 3.5 0.0 2.6 2.4 77.0 0.0 33.9 20.9 0.1 18.2 8.3 16.9 6.2 59.3 0.9 0.0 0.1 26.7 0.0 7.0 12.3 0.1 7.0 9.7 6.4 0.0 0.9 0.0 0.9 0.0 1.4 8.5 4.2 5.3 0.1 10.3 14.9 0.0 0.0 0.0 4.4 9.5 0.2 0.0 5.6 5.9 1.7 0.1 8.5 0.0 25.8 4.3 13.2 0.0 6.2 1.3 1.3 6.2 2.9 0.0 0.0 1.7 3.2 38.4 1.0 0.0 0.1 0.0 6.9 0.0 3.6 1.6 0.0 0.0 1.7 0.0 1.7 1.3 2.5 1.7 0.0 1.2 1.0 0.2 0.1 3.5 0.0 0.1 1.2 0.4 0.0 3.9 0.0 23.8 20.9 0.0 0.0 1.5 0.0 0.0 3.7 0.0 36.3 0.0 6.4 51.9 8.2 6.1 0.7 9.7 2.8 9.8 4.3 6.0 31.6 7.2 13.7 9.2 0.0 0.1 12.2 4.7 7.9 0.2 3.9 1.9 5.7 26.3 3.5 0.0 317.9 0.2 0.0 5.1 4.6 5.2 1.3 9.0 20.0 0.4 0.3 1.7 68.8 12.8 8.2 0.0 1.5 5.8 1.2 0.9 7.2 70.3 0.2 7.2 3.1 8.0 7.9 30.9 3.6 8.6 2.1 1.4 0.1 1.7 4.5 3.2 0.0 3.6 10.2 10.0 1.9 4.1 12.5 0.0 5.4 11.3 6.6 2.4 EPHX1 EPHX ENSG00000143819 "Epoxide hydrolase 1" P07099 1 225810124-225845563 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1178.6;liver: 1705.1" "Cell type enhanced" "Detected in many" "Granulosa cells: 349.9;Hepatocytes: 757.6;Theca cells: 1042.6" "Cancer enriched" "Detected in all" 6 "liver cancer: 1047.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 1161.8;SiHa: 413.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020593, HPA048847" Enhanced NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA020593: AB_10601373, HPA048847: AB_2680538" "unprognostic (2.85e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.53e-3)" "unprognostic (2.50e-1)" "unprognostic (6.60e-2)" "unprognostic (3.92e-2)" "prognostic favorable (7.02e-5)" "unprognostic (1.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.32e-4)" "unprognostic (8.10e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "unprognostic (1.88e-2)" 245.8 1178.6 233.5 23.6 252.5 22.7 163.7 239.0 249.3 188.3 345.8 82.0 102.2 108.1 97.6 159.6 153.8 96.5 94.0 221.3 233.7 110.7 1705.1 146.8 39.1 225.3 234.9 329.1 536.1 147.7 105.8 32.9 223.6 113.2 52.5 30.7 143.6 128.1 142.5 71.5 52.8 109.6 210.1 55.7 99.9 74.3 258.4 25.9 171.1 95.6 33.4 135.4 140.4 227.2 32.1 202.3 12.3 108.5 1161.8 120.2 24.3 29.7 49.2 28.1 35.1 38.8 293.6 1.3 128.7 147.3 30.6 38.1 32.7 16.8 12.1 7.8 46.5 21.8 83.5 282.7 129.8 12.9 15.1 109.2 40.0 74.6 6.3 116.5 22.1 13.4 14.5 27.3 50.4 30.3 13.5 31.0 61.6 178.1 79.4 27.8 15.2 92.9 91.1 132.5 98.3 13.0 413.0 192.1 51.3 32.1 131.7 43.5 46.8 41.9 35.4 54.5 59.0 9.1 38.9 4.1 63.5 14.2 59.5 0.0 2.6 0.1 0.2 0.7 0.4 0.1 0.3 0.2 0.6 0.2 0.5 0.3 0.2 0.7 0.3 0.9 0.3 0.8 233.5 252.5 239.0 249.3 221.3 233.7 225.3 234.9 223.6 210.1 258.4 227.2 196.9 0.0 14.0 41.1 5.7 19.6 121.8 244.2 74.0 8.8 29.7 27.4 1.2 102.9 255.5 51.5 29.2 46.6 3.4 34.5 17.6 95.3 10.2 142.9 32.2 82.7 10.8 7.0 3.1 73.0 7.6 175.6 30.5 93.4 5.7 349.9 88.2 757.6 149.1 1.7 5.0 17.5 103.7 30.9 28.7 28.4 311.3 25.8 42.7 23.4 9.6 99.2 0.0 7.1 19.4 45.5 27.2 159.1 9.5 40.4 63.4 128.9 174.3 10.1 223.5 29.3 146.9 4.4 5.1 129.0 17.6 22.8 4.7 1042.6 31.5 108.5 EPS8 ENSG00000151491 "Epidermal growth factor receptor pathway substrate 8" Q12929 12 15620134-15882329 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 317.0;Sertoli cells: 401.0;Smooth muscle cells: 313.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 22.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 253.0;HHSteC: 218.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003897 Approved Approved "Golgi apparatus" NA NA 17000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA003897: AB_1848224" "unprognostic (6.16e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-2)" "unprognostic (5.43e-2)" "unprognostic (2.46e-1)" "unprognostic (1.04e-1)" "unprognostic (5.81e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (3.33e-7)" "unprognostic (2.68e-1)" "prognostic favorable (1.45e-7)" "unprognostic (7.47e-3)" "unprognostic (7.20e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.79e-2)" 62.3 13.0 12.9 16.1 17.4 0.6 33.7 15.3 14.0 53.9 14.1 49.7 37.6 46.2 47.1 20.5 20.1 56.0 26.4 11.1 17.2 55.8 37.8 29.0 9.4 18.5 20.1 49.2 15.1 21.6 3.5 53.1 19.7 16.4 53.7 39.8 13.4 39.8 13.8 11.9 42.7 53.7 15.5 11.9 32.0 15.6 16.1 4.8 22.8 24.3 5.2 51.7 21.4 20.8 65.0 38.8 37.7 1.4 253.0 177.6 53.1 73.6 59.8 34.5 46.1 33.3 97.3 0.0 2.4 140.4 114.4 16.4 11.3 9.5 52.4 0.2 12.6 5.7 11.2 34.7 218.1 4.4 0.2 159.8 42.8 91.7 115.7 44.6 17.7 0.2 0.1 0.2 169.0 17.5 0.2 2.8 5.2 50.3 30.8 0.0 109.5 0.8 97.7 92.5 3.1 4.9 21.4 12.4 91.5 6.2 34.2 4.3 28.7 54.7 14.3 32.4 30.7 3.6 0.4 0.1 32.1 10.7 160.0 0.0 2.7 0.2 0.2 10.8 0.1 1.3 0.9 0.4 5.5 0.3 1.1 0.5 4.4 1.0 22.2 0.4 0.1 1.7 12.9 17.4 15.3 14.0 11.1 17.2 18.5 20.1 19.7 15.5 16.1 20.8 121.4 12.8 175.9 91.1 11.6 17.0 39.6 32.0 13.6 9.7 28.7 42.8 27.6 87.2 58.3 23.9 66.7 33.0 15.2 317.0 60.7 69.4 67.6 87.4 72.0 61.4 38.3 0.4 2.2 68.9 7.3 73.4 81.1 152.2 6.3 139.4 36.0 36.0 65.8 6.7 31.1 54.5 67.1 54.1 35.6 49.4 134.8 46.2 35.6 148.0 8.6 15.4 0.0 121.2 96.9 97.0 217.8 43.6 5.2 26.9 69.0 114.6 104.8 153.7 401.0 18.1 313.1 10.9 4.2 22.8 13.1 21.1 11.8 40.0 80.0 97.6 ERP44 "KIAA0573, PDIA10, TXNDC4" ENSG00000023318 "Endoplasmic reticulum protein 44" Q9BS26 9 99979185-100099000 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001318 Supported "Intracellular and membrane" NA NA 5300000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "HPA001318: AB_1080427" "unprognostic (8.28e-2)" "unprognostic (1.32e-1)" "unprognostic (5.56e-2)" "unprognostic (5.97e-3)" "unprognostic (1.55e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (1.29e-1)" "unprognostic (3.88e-2)" "unprognostic (2.58e-1)" "unprognostic (2.00e-2)" "unprognostic (5.38e-2)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "unprognostic (1.66e-1)" "unprognostic (3.90e-1)" "unprognostic (2.31e-1)" 18.4 17.3 8.1 17.7 8.5 21.3 16.2 12.9 10.5 19.5 10.1 22.0 22.4 15.2 39.3 17.8 13.7 16.7 15.9 8.2 9.1 18.0 34.2 18.6 17.9 8.0 8.7 12.4 27.4 18.7 13.3 32.6 8.5 18.9 23.6 15.8 20.8 18.3 11.6 12.9 23.8 16.8 8.4 18.4 24.1 10.6 8.6 14.6 27.1 11.6 18.6 19.3 14.1 9.0 18.5 14.7 20.7 23.6 73.5 34.9 37.6 39.9 54.2 27.6 36.3 31.2 52.4 47.3 25.7 45.5 41.1 65.9 25.7 28.1 24.9 24.5 14.4 17.8 14.3 22.8 64.3 32.2 27.0 39.4 41.5 24.2 34.7 26.2 34.2 15.7 34.7 35.7 22.7 28.8 22.1 22.6 21.5 72.0 18.9 19.2 34.7 32.9 35.9 20.9 16.2 18.9 32.8 40.2 28.9 30.5 15.0 32.8 23.8 20.5 19.2 27.4 17.7 20.5 19.3 15.8 31.3 21.0 28.3 32.8 45.7 42.7 20.2 49.2 19.5 28.1 19.9 22.1 37.4 26.5 15.1 17.6 41.5 27.4 62.3 23.4 23.5 37.7 8.1 8.5 12.9 10.5 8.2 9.1 8.0 8.7 8.5 8.4 8.6 9.0 72.3 54.5 41.8 38.8 77.5 43.3 80.3 146.6 29.0 34.3 33.9 25.3 34.7 54.3 84.6 33.1 18.8 141.4 72.5 90.0 17.6 104.4 8.4 42.2 61.4 62.5 53.1 38.3 69.4 111.8 150.5 72.0 57.1 62.3 71.0 54.2 64.6 73.3 165.7 30.3 70.0 118.1 73.2 79.5 101.9 7.7 61.2 102.2 64.0 85.3 128.5 32.7 61.8 45.8 68.9 92.8 90.0 67.7 97.9 75.9 111.2 51.4 60.2 30.6 72.3 48.9 95.9 83.3 41.4 40.0 49.6 229.3 60.3 87.5 88.9 84.2 ETFBKMT "C12orf72, DKFZp451L235, METTL20, MGC50559" ENSG00000139160 "Electron transfer flavoprotein subunit beta lysine methyltransferase" Q8IXQ9 12 31647160-31673114 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 7.3;Distal tubular cells: 7.9;Endometrial ciliated cells: 10.3;Proximal tubular cells: 18.1;Theca cells: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039024 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" "HPA039024: AB_10670917" "unprognostic (1.05e-1)" "unprognostic (6.46e-2)" "unprognostic (1.16e-1)" "unprognostic (7.91e-3)" "unprognostic (1.93e-1)" "unprognostic (6.13e-2)" "unprognostic (3.49e-4)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.72e-2)" "unprognostic (7.82e-3)" "unprognostic (2.77e-1)" "unprognostic (6.12e-5)" "unprognostic (3.68e-1)" "unprognostic (1.18e-1)" "unprognostic (8.69e-2)" "unprognostic (1.32e-2)" 2.4 3.8 2.0 1.6 2.3 2.3 2.9 3.1 2.7 3.7 0.7 2.4 2.9 2.8 5.4 2.5 4.4 2.7 3.7 1.8 1.8 6.1 9.7 2.1 1.6 1.6 1.7 4.8 3.8 4.7 2.6 2.1 1.7 2.6 2.5 6.1 2.2 2.7 7.6 2.5 2.0 3.0 1.8 2.4 2.7 3.7 1.7 1.0 3.7 7.8 1.4 2.1 1.6 2.9 1.8 1.1 1.6 2.3 6.8 4.7 1.4 1.7 1.7 1.9 2.1 2.1 3.2 0.8 1.6 1.2 1.7 0.4 1.0 1.2 2.0 1.3 1.2 1.3 1.6 0.6 2.4 0.8 1.8 4.4 2.1 2.3 2.1 1.8 3.0 2.5 1.5 2.9 2.4 1.7 0.8 0.8 1.8 1.5 1.9 1.2 2.0 2.2 2.7 0.6 1.0 1.0 1.6 1.2 2.6 4.1 5.1 1.6 2.3 1.9 1.7 5.0 1.4 5.3 3.2 1.4 1.6 1.5 1.5 7.8 1.7 2.1 0.9 1.0 0.8 2.0 1.1 1.5 1.2 2.3 1.8 1.6 4.5 1.6 1.2 2.5 1.3 0.9 2.0 2.3 3.1 2.7 1.8 1.8 1.6 1.7 1.7 1.8 1.7 2.9 5.9 6.4 3.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 7.3 6.3 0.0 0.0 0.6 3.7 0.0 3.0 2.5 0.0 7.9 2.9 0.0 10.3 5.2 2.1 0.0 0.0 0.0 2.6 2.6 2.1 0.0 5.3 2.5 5.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.5 0.0 0.0 18.1 3.6 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.7 1.6 7.6 0.0 0.0 EZH1 "KIAA0388, KMT6B" ENSG00000108799 "Enhancer of zeste 1 polycomb repressive complex 2 subunit" Q92800 17 42700275-42745049 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 133.4" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 258.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 48.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005478, HPA077684" Supported Supported Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA005478: AB_1848340, HPA077684: AB_2732356" "unprognostic (1.01e-1)" "unprognostic (6.02e-2)" "unprognostic (2.19e-2)" "unprognostic (8.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.84e-3)" "unprognostic (1.76e-2)" "unprognostic (1.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.55e-3)" "unprognostic (5.22e-3)" "unprognostic (4.11e-3)" "unprognostic (1.48e-2)" "unprognostic (4.60e-2)" "unprognostic (3.29e-1)" "unprognostic (5.39e-2)" "unprognostic (4.74e-2)" 39.6 18.1 35.0 14.4 37.4 15.2 34.1 42.4 41.5 41.5 29.4 31.6 13.0 31.1 26.5 21.6 35.6 12.8 31.8 33.9 33.9 28.6 13.4 25.7 20.5 37.7 36.5 47.8 18.3 25.5 26.3 12.5 40.2 26.0 15.4 133.4 20.2 23.8 43.8 26.1 30.6 20.4 32.3 37.8 20.7 12.0 35.8 22.9 28.4 33.2 20.4 29.2 31.4 41.5 8.9 9.3 12.4 8.5 48.4 29.1 10.4 14.0 12.7 11.4 11.6 4.4 10.8 13.4 8.6 15.0 11.2 19.8 8.1 9.2 16.3 15.0 14.5 4.7 19.7 5.4 16.6 10.2 10.8 16.7 16.6 8.6 20.8 20.0 9.4 13.4 12.5 18.5 10.2 3.7 16.6 12.9 3.4 8.2 4.7 10.7 12.4 14.5 11.7 9.3 8.4 6.8 7.8 3.8 9.5 17.5 13.2 6.5 9.8 12.2 5.0 14.4 8.9 19.3 10.4 8.0 8.8 10.4 6.4 14.2 5.2 7.8 6.0 5.4 8.2 5.8 5.3 6.1 2.0 6.3 7.7 5.8 19.7 5.8 3.6 6.3 6.4 2.6 35.0 37.4 42.4 41.5 33.9 33.9 37.7 36.5 40.2 32.3 35.8 41.5 34.2 9.6 20.8 41.1 23.6 5.2 14.2 6.6 8.6 71.7 8.7 13.1 39.3 20.0 14.1 12.9 66.7 7.9 24.6 9.3 9.8 11.2 0.7 21.8 23.2 20.7 13.1 36.4 36.8 7.5 3.2 25.3 8.6 25.5 20.3 19.4 15.4 7.8 9.0 47.1 34.0 4.9 12.2 17.1 7.2 2.8 31.1 14.7 1.8 15.0 24.1 30.8 33.0 20.6 58.9 12.1 7.7 34.3 15.9 9.1 12.9 10.7 28.0 258.1 52.6 32.7 24.1 10.7 10.6 6.6 6.1 10.8 21.8 26.2 7.4 9.6 FABP3 "FABP11, H-FABP, MDGI, O-FABP" ENSG00000121769 "Fatty acid binding protein 3" P05413 1 31365253-31376850 "Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "heart muscle: 5666.1;skeletal muscle: 2202.5;tongue: 1442.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 629.8;Cardiomyocytes: 2495.2;Distal tubular cells: 452.0;Proximal tubular cells: 703.6" "Cancer enhanced" "Detected in all" "renal cancer: 92.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "ASC TERT1: 215.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017830, HPA055754" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Focal adhesion sites" NA NA 1640000 3000000 "Cluster 22: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Focal adhesion sites" "Golgi apparatus, Plasma membrane" "CAB017830: , HPA055754: AB_2682909" "unprognostic (2.07e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.73e-2)" "unprognostic (2.05e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-3)" "unprognostic (1.04e-1)" "unprognostic (6.86e-2)" "unprognostic (1.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.67e-1)" "prognostic favorable (1.54e-7)" "unprognostic (5.80e-3)" "unprognostic (3.45e-1)" "unprognostic (7.38e-3)" "unprognostic (9.76e-3)" 31.4 63.5 33.7 2.1 39.2 1.6 95.4 42.3 51.5 40.4 14.8 16.3 0.8 93.9 6.4 9.5 37.2 3.7 5666.1 52.0 37.3 229.8 6.6 26.4 3.4 50.5 38.3 20.3 2.2 0.3 9.0 2.8 55.2 48.9 4.8 17.8 46.5 52.2 2202.5 16.3 7.5 44.2 31.4 28.8 60.3 15.3 36.1 2.3 6.8 1442.4 1.4 12.5 32.5 36.8 1.0 0.4 8.8 1.1 50.6 215.0 2.0 2.6 17.3 0.3 6.6 1.3 1.9 1.6 17.8 5.2 0.3 2.1 2.5 0.0 0.5 0.8 3.7 1.8 2.7 5.3 2.2 1.7 0.5 16.9 0.0 3.9 0.0 2.5 0.0 1.4 2.2 0.5 2.2 0.5 0.7 1.5 11.4 0.9 3.1 0.4 5.7 0.6 4.1 0.7 2.1 0.5 1.5 0.7 28.4 13.2 0.9 3.1 1.7 1.0 1.0 6.0 1.3 1.0 2.3 1.3 2.9 1.5 1.7 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.3 0.1 0.2 0.1 0.4 0.0 0.2 0.1 0.1 0.1 0.1 33.7 39.2 42.3 51.5 52.0 37.3 50.5 38.3 55.2 31.4 36.1 36.8 4.9 0.0 1.7 2.9 7.7 3.6 1.5 0.4 0.0 6.1 629.8 13.2 2495.2 2.8 1.3 27.6 2.1 3.8 2.1 0.4 452.0 0.4 2.5 0.4 0.5 25.6 0.0 0.0 16.1 0.4 1.4 67.2 1.1 3.1 1.3 43.8 2.2 0.1 114.7 8.4 14.6 0.1 0.0 27.8 10.3 5.4 6.8 19.1 8.8 3.7 0.0 2.6 0.0 3.5 8.9 0.3 12.3 7.9 0.1 6.8 0.1 703.6 1.5 10.2 0.0 14.9 40.7 2.9 0.2 0.2 3.0 1.6 5.1 97.9 0.3 36.5 FABP4 "A-FABP, aP2" ENSG00000170323 "Fatty acid binding protein 4" P15090 8 81478419-81483236 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "adipose tissue: 3787.4;breast: 2195.7" "Cell type enriched" "Detected in many" 17 "Adipocytes: 24359.7" "Group enriched" "Detected in all" 7 "breast cancer: 42.1;cervical cancer: 141.7;head and neck cancer: 133.8;urothelial cancer: 65.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 171 "ASC diff: 4051.5;RT4: 2107.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA002188, CAB024961" Enhanced NA NA 22000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB024961: , HPA002188: AB_1078822" "unprognostic (4.81e-2)" "unprognostic (2.30e-3)" "unprognostic (1.64e-3)" "unprognostic (2.63e-2)" "unprognostic (2.58e-1)" "unprognostic (8.70e-3)" "unprognostic (1.78e-3)" "unprognostic (1.67e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" "unprognostic (8.76e-2)" "unprognostic (1.13e-3)" "unprognostic (4.48e-2)" "unprognostic (2.26e-2)" "unprognostic (1.39e-1)" 3787.4 42.2 0.8 46.7 1.1 2.8 2195.7 0.9 1.6 9.9 34.8 52.9 2.8 4.6 0.6 15.1 10.9 68.1 121.8 1.2 0.8 7.0 5.1 113.5 13.6 0.8 0.8 4.2 16.6 59.1 1.4 186.9 0.8 4.3 33.5 2.6 58.8 5.0 66.7 65.2 44.7 14.2 0.7 6.7 26.5 1.1 3.8 29.8 83.0 166.7 2.0 242.7 18.9 0.9 0.0 0.0 0.0 0.0 4051.5 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 17.9 0.0 0.1 1.3 0.0 0.4 0.0 0.0 2.0 0.7 0.0 0.0 0.0 0.8 1.2 0.1 3.0 0.0 9.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 2107.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.2 5.7 0.0 0.2 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.9 1.6 1.2 0.8 0.8 0.8 0.8 0.7 3.8 0.9 24359.7 35.3 64.3 0.0 19.4 14.4 1.1 0.9 4.6 0.5 71.7 196.2 42.1 0.0 26.7 0.0 0.0 0.5 73.6 0.0 0.0 0.2 1.6 0.4 8.8 1132.7 0.0 0.0 0.0 5.6 0.7 53.1 1.1 0.2 27.8 0.1 23.2 0.4 114.2 0.0 0.0 0.0 0.0 50.4 15.7 10.9 1.5 192.7 16.0 0.0 0.6 0.9 0.0 0.0 0.0 0.2 2.2 1.2 2.7 0.5 0.0 0.3 21.9 2.4 716.6 62.2 1364.8 0.0 0.1 1.2 13.9 0.7 18.7 2.3 0.0 55.3 FADS1 "D5D, FADS6, FADSD5, LLCDL1, TU12" ENSG00000149485 "Fatty acid desaturase 1" O60427 11 61799627-61829318 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 521.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042705 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA042705: AB_10795709" "unprognostic (8.28e-2)" "unprognostic (3.54e-1)" "unprognostic (1.29e-1)" "unprognostic (1.99e-1)" "unprognostic (8.17e-3)" "unprognostic (1.40e-1)" "unprognostic (1.99e-2)" "unprognostic (3.23e-3)" "unprognostic (7.88e-2)" "unprognostic (1.94e-2)" "unprognostic (4.10e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.95e-9)" "unprognostic (2.29e-2)" "unprognostic (3.59e-2)" "prognostic unfavorable (2.79e-4)" "prognostic unfavorable (1.33e-4)" 26.2 67.7 43.1 19.8 39.2 9.7 13.6 38.4 40.7 19.6 70.7 9.5 5.5 21.3 6.6 5.2 17.4 14.5 22.6 39.3 58.5 9.7 52.8 20.3 9.8 57.9 62.1 27.5 10.0 27.2 21.3 21.1 52.2 19.6 4.9 35.1 6.4 15.8 17.5 15.5 6.7 20.5 46.4 8.0 9.4 11.9 68.7 8.1 6.0 7.8 9.2 12.7 10.2 56.0 66.3 170.1 159.1 41.1 313.2 521.2 46.4 42.0 204.5 69.9 118.9 53.3 143.2 2.3 43.4 60.5 177.2 84.7 130.8 114.1 51.7 12.2 18.4 107.9 191.2 98.9 169.1 23.4 10.4 238.1 38.3 154.7 74.7 73.8 64.1 104.7 59.9 118.6 70.1 18.6 78.6 23.6 94.2 5.5 63.0 85.4 162.5 231.2 81.5 29.0 80.7 89.6 106.7 1.7 90.0 58.4 38.6 98.6 62.1 71.8 70.8 74.2 50.6 112.9 111.3 55.4 42.6 108.9 61.4 7.5 33.2 6.2 12.1 40.4 2.6 2.5 4.0 4.9 28.0 8.7 2.3 5.4 2.6 6.9 17.4 23.6 2.9 15.7 43.1 39.2 38.4 40.7 39.3 58.5 57.9 62.1 52.2 46.4 68.7 56.0 10.3 6.4 77.9 28.7 3.2 2.7 2.5 48.5 1.2 78.9 2.6 3.7 30.4 8.6 25.3 12.9 27.1 9.5 12.4 0.9 0.0 15.2 8.7 4.9 30.7 16.6 9.7 46.3 9.4 33.4 50.0 34.9 6.1 7.8 37.9 65.3 9.3 74.5 37.2 69.0 14.7 0.6 16.2 21.7 21.0 16.4 29.8 27.6 32.0 12.2 32.0 70.5 6.2 13.6 27.4 7.6 0.0 21.4 2.1 6.4 0.1 1.1 8.0 91.9 0.0 40.3 31.9 6.5 17.5 2.3 1.4 9.3 5.5 75.2 1.4 1.6 FADS2 "D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13" ENSG00000134824 "Fatty acid desaturase 2" O95864 11 61792980-61867354 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 364.1" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Endometrial stromal cells: 57.7;Hepatocytes: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 1141.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006741 Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA006741: AB_1078796" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (8.34e-2)" "unprognostic (4.33e-3)" "unprognostic (4.63e-2)" "unprognostic (2.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.35e-3)" "unprognostic (2.01e-1)" "unprognostic (4.21e-2)" "unprognostic (8.95e-3)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.00e-7)" "unprognostic (6.19e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-2)" "prognostic unfavorable (3.42e-4)" 23.7 364.1 140.2 34.7 126.7 28.0 59.6 128.5 135.0 68.0 157.0 24.2 31.9 86.3 27.7 10.6 34.6 20.2 27.7 131.8 164.8 20.3 126.7 33.4 16.5 175.1 186.2 29.1 9.8 80.0 50.8 40.6 155.1 97.7 13.2 41.5 24.3 188.7 12.3 131.6 15.9 125.3 152.0 11.5 14.1 27.8 222.9 34.1 10.4 8.8 31.2 24.6 27.9 134.2 14.6 492.6 655.8 345.0 551.3 1141.8 167.2 86.3 658.3 109.0 288.2 31.4 149.6 3.8 11.4 172.3 167.8 15.7 436.4 709.5 52.7 6.9 11.8 297.9 106.5 72.0 421.9 18.9 15.9 430.9 25.8 383.4 39.1 170.3 324.4 254.4 17.9 212.1 52.0 13.5 166.4 104.7 291.5 0.7 150.1 206.1 13.9 663.1 392.1 4.4 197.4 260.8 49.9 1.4 23.5 164.0 21.5 197.7 139.2 14.0 120.5 9.8 13.1 115.7 110.3 39.7 13.0 96.3 131.2 4.4 6.0 6.9 8.5 8.7 2.0 1.4 3.1 4.6 10.1 3.7 1.8 3.8 2.8 6.6 7.4 13.0 2.9 4.9 140.2 126.7 128.5 135.0 131.8 164.8 175.1 186.2 155.1 152.0 222.9 134.2 3.2 9.6 18.8 69.9 2.0 1.7 1.3 26.9 0.0 9.1 4.7 3.0 4.2 1.5 15.1 3.7 4.2 1.7 5.2 0.5 0.0 6.9 2.2 4.7 57.7 12.2 5.4 26.7 7.4 17.8 22.0 21.0 5.1 9.5 5.1 28.3 2.5 55.8 20.5 5.0 7.7 0.2 22.4 7.2 3.1 5.3 25.7 7.0 8.8 15.0 20.7 32.1 8.2 38.7 11.9 5.1 0.0 23.7 1.4 16.9 0.1 0.7 5.4 13.2 0.0 23.8 29.5 1.3 0.5 1.2 0.6 3.1 2.5 28.3 2.0 0.9 FAM122A "C9orf42, MGC17347" ENSG00000187866 "Family with sequence similarity 122A" Q96E09 9 68780065-68785566 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056646 Approved Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" Nucleoplasm "HPA056646: AB_2683202" "unprognostic (1.88e-2)" "unprognostic (7.62e-2)" "unprognostic (9.17e-2)" "unprognostic (1.48e-2)" "unprognostic (2.55e-2)" "unprognostic (1.16e-1)" "unprognostic (9.79e-2)" "unprognostic (1.45e-2)" "unprognostic (4.18e-1)" "unprognostic (8.49e-3)" "unprognostic (1.45e-2)" "unprognostic (4.58e-3)" "prognostic favorable (1.34e-5)" "unprognostic (9.35e-2)" "unprognostic (3.02e-2)" "unprognostic (2.72e-1)" "unprognostic (6.89e-2)" 9.9 9.3 4.6 5.8 4.9 5.3 9.7 8.2 6.3 9.7 15.0 7.9 4.4 9.3 6.7 8.3 8.5 5.6 9.0 5.4 5.4 9.7 9.9 6.8 7.4 5.1 5.4 10.5 8.9 11.0 6.8 10.2 5.1 7.7 6.5 6.8 8.2 8.4 8.9 7.6 7.4 7.8 4.4 8.3 7.4 4.9 5.0 6.5 8.5 8.6 7.2 7.2 8.0 5.0 5.2 3.4 4.8 4.1 15.9 10.3 6.4 7.3 6.9 6.3 5.0 1.2 2.5 11.0 3.5 7.7 4.5 9.6 5.3 4.9 7.8 11.9 5.6 6.1 6.0 4.4 9.7 11.2 4.1 8.4 11.0 5.8 4.5 7.1 6.3 7.8 6.5 12.1 6.8 2.9 6.3 2.9 6.0 12.4 6.2 7.6 6.6 3.4 5.7 4.3 7.6 3.4 5.4 4.5 3.8 6.6 2.7 4.8 8.0 5.8 4.2 11.0 5.5 14.2 6.1 4.4 6.3 6.9 6.7 1.9 2.0 1.5 1.7 1.9 1.4 1.5 1.7 1.8 2.2 2.5 3.5 2.0 1.1 1.8 1.9 2.6 2.0 1.0 4.6 4.9 8.2 6.3 5.4 5.4 5.1 5.4 5.1 4.4 5.0 5.0 10.0 3.2 9.8 0.0 19.6 23.6 18.7 13.3 20.5 18.8 18.2 17.0 15.9 10.0 13.1 5.5 16.7 28.2 11.8 11.3 66.5 18.3 32.0 10.4 20.2 17.2 18.0 27.0 0.0 13.8 17.0 13.9 14.3 8.1 17.7 12.7 17.2 18.6 21.6 8.4 0.0 17.0 10.2 22.3 17.0 15.4 15.2 15.0 14.2 0.0 16.8 38.3 24.7 0.0 0.0 12.9 15.8 17.0 18.3 11.9 11.1 27.2 23.0 19.8 46.0 18.8 43.9 52.4 21.3 19.5 23.7 30.6 16.8 23.1 15.3 17.8 FAM13A "ARHGAP48, FAM13A1, KIAA0914" ENSG00000138640 "Family with sequence similarity 13 member A" O94988 4 88725955-89111398 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 178.0;Oligodendrocyte precursor cells: 157.8;Syncytiotrophoblasts: 279.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038108, HPA038109" Uncertain Approved "Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions, Cytosol" Nucleoli "HPA038108: AB_2675837, HPA038109: AB_10672619" "unprognostic (1.14e-1)" "unprognostic (1.53e-2)" "unprognostic (6.29e-2)" "unprognostic (2.53e-1)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (3.79e-1)" "unprognostic (2.81e-1)" "unprognostic (8.20e-2)" "unprognostic (1.75e-1)" "unprognostic (1.46e-3)" "unprognostic (6.36e-2)" "unprognostic (4.71e-1)" "unprognostic (3.49e-3)" "unprognostic (1.90e-2)" "unprognostic (7.44e-2)" "prognostic favorable (4.28e-4)" 49.2 12.8 8.5 9.9 9.0 12.7 31.8 14.2 11.8 17.6 13.2 18.3 50.5 12.5 7.5 7.6 23.5 16.3 9.9 9.7 7.3 21.9 39.1 11.8 6.3 8.6 8.4 27.8 38.6 49.2 8.4 35.1 9.5 10.6 14.8 15.9 23.4 10.5 9.7 20.4 29.0 13.3 8.3 5.4 16.3 13.9 9.0 5.6 32.8 21.9 4.8 16.9 10.4 8.8 4.5 6.7 9.8 12.8 55.5 22.7 16.0 10.2 12.4 4.0 3.6 5.6 10.3 0.1 4.0 7.4 6.3 2.7 14.5 7.4 8.9 0.6 10.0 7.5 8.9 0.7 16.3 6.3 1.0 21.9 5.9 10.1 3.6 17.5 6.9 2.5 19.7 0.7 8.7 0.2 0.7 2.8 12.1 0.8 6.9 10.2 16.6 4.0 7.4 21.8 24.6 6.5 2.5 7.9 9.9 9.6 5.5 0.2 2.5 11.2 6.2 5.5 5.9 3.4 2.1 0.1 16.6 0.6 5.9 0.0 4.1 0.0 1.0 2.0 0.7 0.0 2.7 0.3 3.5 0.0 2.9 0.7 0.9 0.4 0.6 1.2 1.5 1.6 8.5 9.0 14.2 11.8 9.7 7.3 8.6 8.4 9.5 8.3 9.0 8.8 42.6 12.8 34.9 95.3 4.3 10.1 22.3 20.4 28.5 16.3 29.7 20.6 25.9 38.6 39.3 11.0 35.5 72.9 12.9 50.4 29.4 10.7 3.4 82.0 33.6 14.1 4.9 31.3 178.0 16.9 35.3 42.1 33.1 98.2 1.3 70.2 12.8 143.0 20.7 0.0 46.5 54.1 26.4 29.6 11.9 5.1 45.1 21.7 19.6 104.9 16.9 22.6 5.2 157.8 17.4 20.7 73.4 33.4 10.3 13.6 37.5 50.4 74.6 11.3 0.0 24.7 31.9 5.3 10.2 14.4 7.7 279.5 9.7 41.2 22.3 19.5 FAM20A DKFZp434F2322 ENSG00000108950 "FAM20A golgi associated secretory pathway pseudokinase" Q96MK3 17 68535113-68601367 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 50.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 82.4;Early spermatids: 69.0;Hepatocytes: 66.8;Hofbauer cells: 94.0;Late spermatids: 189.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 10.1;BJ hTERT+: 27.3;HSkMC: 21.8;U-2197: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048964 Approved "Secreted in other tissues" NA NA 13000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "HPA048964: AB_2680575" "unprognostic (3.68e-2)" "unprognostic (3.14e-2)" "unprognostic (3.35e-2)" "unprognostic (4.49e-3)" "unprognostic (6.56e-2)" "unprognostic (5.29e-2)" "unprognostic (3.90e-3)" "unprognostic (2.39e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (9.16e-10)" "unprognostic (1.25e-3)" "unprognostic (1.06e-1)" "unprognostic (4.55e-2)" "unprognostic (2.39e-2)" 7.5 1.6 0.4 2.7 0.3 0.6 5.4 0.3 0.6 17.5 2.6 1.6 0.6 12.5 0.1 3.1 6.0 1.3 3.1 0.1 1.1 12.9 50.2 12.6 1.6 0.8 1.7 8.1 1.0 0.3 6.3 2.2 0.7 2.5 0.4 0.1 11.6 0.6 1.6 2.5 2.0 2.3 0.1 4.5 7.8 6.5 3.6 0.4 6.8 0.1 0.5 2.2 5.7 0.7 0.0 0.2 0.0 0.2 1.1 10.1 0.0 0.5 27.3 0.0 0.0 0.0 0.1 0.0 2.0 2.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.1 0.0 21.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.1 0.0 0.0 0.1 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.4 0.3 0.3 0.6 0.1 1.1 0.8 1.7 0.7 0.1 3.6 0.7 1.4 16.0 82.4 0.7 1.1 2.3 0.1 5.2 0.0 3.2 5.3 0.9 5.2 7.2 21.3 44.1 0.0 0.6 0.4 0.0 0.0 1.2 69.0 6.1 44.4 3.6 0.0 2.7 3.8 0.5 2.2 18.1 42.3 9.7 1.3 2.9 7.5 66.8 94.0 42.1 8.2 0.0 2.0 27.4 3.5 189.3 11.1 26.8 1.8 16.9 1.3 0.2 0.0 4.0 2.1 0.8 0.0 14.7 0.2 0.0 0.0 15.3 0.8 2.8 6.6 3.4 3.0 1.2 0.6 1.2 1.8 2.7 1.0 13.6 0.0 0.1 FAM20C "DKFZp547D065, DMP4, G-CK, IMAGE:4942737" ENSG00000177706 "FAM20C golgi associated secretory pathway kinase" Q8IXL6 7 192571-260772 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Biomineralization "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 55.2;Hepatocytes: 94.0;Hofbauer cells: 54.9;Peritubular cells: 56.4;Proximal tubular cells: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 55.3;hTERT-RPE1: 39.9;U-87 MG: 36.0;WM-115: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019823 Approved "Nucleoplasm,Golgi apparatus" "Secreted in other tissues" NA NA 240000000 "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Nucleoplasm "HPA019823: AB_1848389" "unprognostic (1.94e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (3.15e-2)" "unprognostic (1.03e-2)" "unprognostic (3.33e-3)" "unprognostic (2.47e-2)" "unprognostic (7.86e-2)" "unprognostic (2.45e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (9.40e-6)" "unprognostic (1.97e-3)" "unprognostic (2.49e-1)" "unprognostic (3.08e-3)" "unprognostic (1.94e-2)" "unprognostic (3.92e-2)" "unprognostic (2.16e-2)" "unprognostic (3.83e-3)" 32.5 14.8 7.0 7.3 5.7 1.5 32.8 5.0 7.0 19.4 0.8 44.3 4.5 19.4 2.1 14.3 20.2 5.9 30.2 4.3 5.0 34.9 56.5 27.9 1.1 12.5 9.7 20.3 13.4 1.6 18.3 2.6 6.7 29.9 1.4 1.1 20.3 3.6 30.7 14.7 23.3 6.8 6.4 8.9 38.9 7.8 12.6 0.6 19.6 6.3 0.6 36.8 15.1 6.2 19.6 6.4 0.3 10.3 11.8 20.3 0.0 17.4 23.2 7.9 5.9 0.9 10.1 0.0 9.3 21.8 10.4 14.9 1.1 0.6 1.6 4.5 0.6 0.0 3.1 3.4 8.8 0.0 1.0 55.3 1.6 0.3 0.7 39.9 5.0 0.0 0.0 0.0 1.8 1.9 0.0 0.7 8.9 0.1 0.3 2.3 0.5 0.0 4.9 0.0 4.4 0.2 17.2 0.0 2.3 1.1 9.7 6.5 14.6 10.3 5.3 7.7 5.3 0.0 0.0 0.0 36.0 1.0 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 5.7 5.0 7.0 4.3 5.0 12.5 9.7 6.7 6.4 12.6 6.2 5.0 6.4 5.1 11.8 1.2 10.1 2.3 4.5 1.8 26.9 27.6 18.7 9.9 21.5 1.0 55.2 0.0 0.5 4.6 3.4 5.9 1.8 0.0 4.1 19.0 4.5 11.9 0.4 7.4 4.8 0.5 22.6 13.7 9.5 3.8 3.1 9.3 94.0 54.9 1.7 17.0 5.3 2.0 24.4 9.8 2.6 16.1 34.5 1.8 5.6 10.8 17.1 0.0 8.5 15.3 6.3 3.7 56.4 0.1 6.6 33.7 48.7 3.4 9.0 13.1 8.7 17.3 0.3 1.0 3.5 8.1 0.5 0.9 0.6 9.0 1.9 FAM219B "C15orf17, FLJ00005" ENSG00000178761 "Family with sequence similarity 219 member B" Q5XKK7 15 74899992-74906883 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048929, HPA058064" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Golgi apparatus" "HPA048929: AB_2680561, HPA058064: AB_2683592" "unprognostic (1.12e-1)" "unprognostic (6.10e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (8.08e-2)" "unprognostic (1.05e-2)" "unprognostic (5.65e-2)" "unprognostic (2.41e-2)" "unprognostic (5.66e-3)" "unprognostic (1.32e-1)" "unprognostic (1.92e-1)" "unprognostic (3.17e-2)" "unprognostic (3.11e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (4.91e-3)" 21.9 19.8 31.5 9.9 30.8 6.4 13.7 31.9 35.5 15.4 32.5 17.1 12.0 16.8 22.5 23.6 22.3 10.6 30.3 31.6 36.3 16.1 6.6 16.9 15.2 32.7 33.6 19.5 13.0 32.4 28.1 13.3 35.0 24.0 14.6 44.7 18.2 17.0 18.7 22.0 13.9 17.8 31.6 24.3 15.3 6.3 34.4 8.5 18.2 25.1 17.4 20.1 16.0 31.3 6.6 9.6 25.9 11.4 42.9 31.6 11.6 18.7 9.8 16.7 10.5 9.1 18.0 12.9 10.4 13.0 16.8 16.8 35.9 10.3 9.1 32.5 20.4 12.3 22.9 7.7 20.3 11.9 16.2 19.2 47.3 7.3 13.7 36.0 18.7 9.6 9.6 15.4 17.1 5.5 7.1 10.4 14.3 19.4 14.4 19.0 9.0 9.7 25.7 21.1 21.7 14.1 20.9 11.6 33.7 27.1 23.3 14.0 21.7 13.5 7.3 11.4 15.2 11.6 12.1 5.5 17.1 24.2 13.8 3.8 1.0 6.9 1.4 0.9 2.4 2.2 2.1 1.2 1.0 2.0 0.9 1.5 1.2 1.8 1.3 0.1 0.2 1.3 31.5 30.8 31.9 35.5 31.6 36.3 32.7 33.6 35.0 31.6 34.4 31.3 13.3 19.2 20.6 22.5 18.4 6.4 21.2 17.9 13.6 41.6 16.2 13.5 5.1 10.0 18.9 27.6 58.4 17.1 22.3 23.3 13.7 14.4 1.0 22.9 14.8 16.0 20.9 7.6 23.9 10.5 11.4 17.4 9.7 13.9 24.7 15.0 17.2 5.8 17.9 23.5 20.8 16.0 28.5 13.3 8.5 4.7 23.3 13.0 14.2 13.1 19.8 26.7 30.9 11.1 9.4 17.5 16.2 28.6 15.7 19.9 23.3 11.9 30.6 69.2 26.3 15.8 15.2 9.1 17.5 18.2 7.7 8.3 16.0 15.0 14.0 22.6 FAM8A1 AHCP ENSG00000137414 "Family with sequence similarity 8 member A1" Q9UBU6 6 17600302-17611715 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Early spermatids: 759.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044698, HPA073675" Approved Approved "Golgi apparatus" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus" "HPA044698: AB_2679051, HPA073675: AB_2732236" "unprognostic (4.06e-1)" "unprognostic (2.32e-1)" "unprognostic (9.11e-2)" "unprognostic (6.90e-2)" "unprognostic (1.99e-2)" "unprognostic (5.17e-3)" "unprognostic (6.13e-2)" "unprognostic (1.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.09e-3)" "unprognostic (4.44e-2)" "unprognostic (3.50e-1)" "unprognostic (1.56e-2)" "unprognostic (3.85e-2)" "unprognostic (3.71e-1)" "unprognostic (7.59e-2)" "unprognostic (2.98e-1)" 18.6 16.1 16.3 10.7 17.3 31.6 19.1 19.0 19.5 20.4 16.6 19.9 16.9 27.3 18.9 13.9 20.6 21.1 14.8 17.4 20.3 24.0 77.9 18.9 10.4 18.2 17.2 27.8 15.0 22.3 13.0 14.9 18.2 20.9 22.8 27.1 23.0 22.3 18.9 14.0 16.7 24.8 20.2 14.3 12.7 17.2 21.1 17.1 23.2 21.7 8.2 14.5 12.6 20.6 9.5 3.7 13.5 32.3 45.6 42.6 11.1 15.0 20.4 7.6 13.1 21.4 3.1 8.1 35.2 25.6 8.3 7.6 20.5 13.0 9.9 6.9 29.1 9.8 12.5 46.2 20.1 6.2 9.6 22.6 20.7 8.7 6.0 24.2 17.0 8.9 20.2 16.2 12.0 11.7 4.6 19.2 5.6 11.6 5.6 12.1 13.0 25.0 25.6 7.5 4.1 21.4 11.7 25.0 23.7 23.1 29.0 9.5 13.3 9.7 3.4 14.9 5.5 13.4 12.0 8.0 8.8 7.1 13.4 2.6 0.3 1.0 1.1 0.4 1.2 0.0 0.5 1.0 0.2 0.1 0.7 1.1 5.5 1.5 0.2 0.2 0.4 0.3 16.3 17.3 19.0 19.5 17.4 20.3 18.2 17.2 18.2 20.2 21.1 20.6 16.8 19.2 27.1 8.8 7.0 13.4 9.7 6.6 14.2 27.6 15.1 13.5 15.3 21.5 12.1 29.5 14.6 10.0 15.7 63.4 5.9 9.2 759.2 26.4 24.0 14.1 12.0 4.2 17.1 7.9 12.0 23.0 10.7 20.6 1.3 8.6 25.4 77.5 6.2 15.2 17.9 10.8 8.2 24.4 6.4 187.8 36.7 8.6 5.4 3.7 8.7 19.3 14.4 8.0 13.8 7.5 25.7 30.9 12.8 7.5 30.4 12.4 20.5 16.7 32.9 20.3 18.7 46.6 18.0 14.3 15.9 12.2 14.0 9.7 16.7 7.8 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4;smooth muscle: 26.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 67.6;Fibroblasts: 43.4;Microglial cells: 17.8;Muller glia cells: 57.5;Smooth muscle cells: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 192.2;ASC TERT1: 202.3;BJ hTERT+: 167.8;hTERT-RPE1: 209.1;U-138 MG: 167.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 3.1;hippocampal formation: 2.4" HPA059739 Uncertain "Secreted to blood" NA NA 108000000 56000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA059739: AB_2684117" "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 5.8 0.2 0.9 5.2 0.9 0.0 10.1 0.4 0.9 15.2 0.0 3.5 0.5 31.4 8.5 3.6 4.8 22.3 4.9 0.3 1.4 0.7 0.2 4.0 1.5 0.6 0.5 3.0 2.5 0.7 0.5 23.1 0.6 1.9 2.5 6.4 4.7 5.8 4.4 2.8 0.9 26.4 0.2 0.4 1.0 1.5 1.0 0.5 2.8 7.5 1.5 15.5 3.6 0.7 0.0 0.0 0.0 0.0 192.2 202.3 0.4 82.8 167.8 16.6 25.4 0.0 0.0 0.0 0.6 31.3 0.0 0.1 0.0 5.1 8.0 0.0 0.0 0.1 1.2 0.0 19.5 0.0 0.0 66.2 1.2 28.1 5.2 209.1 0.1 0.0 0.0 0.0 53.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.5 0.0 9.0 0.2 0.1 0.0 84.3 167.3 3.1 41.4 0.4 0.0 0.1 0.0 37.5 0.1 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.4 0.9 0.3 1.4 0.6 0.5 0.6 0.2 1.0 0.7 3.9 0.0 0.0 5.5 0.2 4.5 0.1 7.0 0.0 1.8 0.3 0.5 0.4 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.2 6.7 3.4 67.6 6.4 4.9 0.0 13.3 0.2 1.9 43.4 0.0 6.2 0.0 0.0 1.4 0.0 0.9 1.7 0.3 1.4 0.0 0.0 2.6 4.1 8.4 0.8 3.6 17.8 0.0 57.5 0.0 0.5 4.2 1.0 0.0 0.0 0.3 0.0 0.0 1.2 0.2 2.0 0.0 4.7 25.2 2.3 0.4 0.4 4.3 1.8 0.8 1.3 0.2 0.0 FAXDC2 "C5orf4, FLJ13758" ENSG00000170271 "Fatty acid hydroxylase domain containing 2" Q96IV6 5 154818492-154859252 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 304.9" "Cell type enhanced" "Detected in many" "Astrocytes: 58.8;Erythroid cells: 93.5;Oligodendrocytes: 164.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 34.8;ASC TERT1: 26.3;HSkMC: 23.2;hTERT-RPE1: 25.3;SK-MEL-30: 24.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 6: Erythroid cells - Oxygen transport" "unprognostic (6.38e-3)" "unprognostic (2.88e-2)" "unprognostic (6.26e-2)" "unprognostic (5.11e-2)" "unprognostic (3.12e-2)" "unprognostic (2.70e-2)" "prognostic favorable (3.87e-5)" "unprognostic (8.29e-2)" "unprognostic (2.52e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (3.42e-2)" "prognostic favorable (9.71e-10)" "unprognostic (1.67e-2)" "unprognostic (1.72e-1)" "unprognostic (1.07e-3)" "unprognostic (3.94e-1)" 34.7 37.5 49.9 5.8 79.0 34.4 27.0 73.6 57.1 24.3 63.0 46.3 8.8 34.7 55.7 16.9 37.4 30.4 34.0 49.0 57.9 25.4 139.7 36.7 7.3 76.4 72.0 59.4 15.0 304.9 12.1 12.6 74.8 28.0 17.8 10.2 40.5 31.0 12.5 21.9 16.2 37.8 60.4 13.3 17.7 12.1 66.6 5.9 36.7 24.3 4.1 19.5 17.2 101.9 1.6 1.3 5.0 10.5 34.8 26.3 3.9 3.7 10.5 1.4 6.4 1.3 13.5 1.9 2.2 5.8 0.3 1.3 0.1 1.7 1.3 1.1 1.7 20.5 3.5 7.4 5.1 2.6 1.7 23.2 6.6 3.3 0.8 25.3 7.9 1.4 11.8 0.3 8.8 0.5 1.5 3.9 2.4 5.0 0.4 1.6 3.3 0.7 2.3 1.4 0.5 9.0 1.6 0.9 24.6 10.6 0.6 0.6 2.8 3.6 2.2 1.5 1.1 1.5 1.1 1.3 5.0 1.5 2.2 3.5 0.8 1.3 0.4 0.6 0.4 0.4 0.5 0.4 1.1 1.1 0.4 0.6 4.2 2.4 0.5 0.6 0.3 6.6 49.9 79.0 73.6 57.1 49.0 57.9 76.4 72.0 74.8 60.4 66.6 101.9 14.3 41.7 11.8 58.8 1.3 2.9 12.3 2.0 7.4 1.6 7.1 8.8 17.8 12.8 6.8 9.2 0.0 4.2 0.3 4.0 9.8 3.4 12.9 6.9 14.9 14.3 3.0 93.5 5.5 0.7 0.4 22.6 2.0 1.9 6.3 14.5 21.8 44.3 2.1 3.3 4.7 29.8 2.0 11.6 9.1 11.2 47.2 17.0 5.4 37.5 2.6 46.8 3.1 51.3 164.8 12.8 5.5 50.8 0.2 4.0 4.2 2.9 15.0 1.8 0.0 24.5 9.4 2.5 0.8 0.7 3.7 1.4 1.9 11.9 1.2 3.8 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 92.7;Endometrial stromal cells: 84.4;Fibroblasts: 458.4;Leydig cells: 170.9;Peritubular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 384.0;fHDF/TERT166: 264.3;HMC-1: 311.6;HSkMC: 221.9;U-2197: 139.2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" 157.3 7.6 5.9 12.7 7.7 1.0 97.3 5.2 9.0 63.4 6.4 32.7 6.2 31.1 3.2 42.4 26.8 46.2 292.8 7.0 4.9 8.7 3.7 29.2 8.4 5.3 5.3 5.8 8.6 3.0 2.3 80.3 4.8 29.1 11.8 0.6 39.4 8.8 47.7 72.5 19.8 14.7 4.1 6.0 22.3 46.7 6.9 14.2 63.7 48.9 5.6 79.6 56.7 4.4 0.0 1.4 50.9 0.0 384.0 51.7 23.8 124.9 98.2 122.4 80.4 8.1 0.3 0.0 5.9 264.3 0.2 0.2 0.0 0.5 22.9 0.1 0.1 100.7 1.9 0.0 26.0 0.2 311.6 221.9 2.0 19.3 0.0 0.2 0.0 8.6 0.8 0.9 0.6 0.3 5.2 0.6 12.2 0.0 0.7 0.2 0.0 0.5 0.9 0.1 3.0 2.4 0.5 90.3 0.1 13.6 0.2 0.3 0.1 0.1 0.1 139.2 0.1 0.2 0.0 0.0 1.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.2 6.7 1.3 0.0 3.7 0.0 0.2 0.0 0.5 0.0 0.9 5.9 7.7 5.2 9.0 7.0 4.9 5.3 5.3 4.8 4.1 6.9 4.4 92.7 0.0 1.5 1.6 3.6 30.8 0.8 10.5 2.2 0.0 1.7 1.9 8.8 0.0 12.3 7.3 2.1 7.8 1.9 0.1 0.0 0.0 3.8 2.9 84.4 43.8 0.0 1.7 0.6 0.2 4.8 458.4 6.1 2.7 23.6 0.6 47.8 0.4 3.6 0.0 0.6 0.0 0.0 1.9 49.8 12.1 170.9 4.5 39.2 26.2 0.3 1.2 0.0 30.7 0.3 0.3 0.0 227.2 1.6 1.2 2.7 0.1 1.4 0.4 13.1 29.7 26.4 3.4 13.5 2.0 28.8 6.2 5.3 0.2 0.0 1.1 FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Fibroblasts: 209.4;Leydig cells: 626.6;Peritubular cells: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "ASC diff: 457.1;ASC TERT1: 234.6;BJ: 202.0;BJ hTERT+: 202.5;fHDF/TERT166: 394.6;HSkMC: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" 182.2 73.4 10.7 17.7 12.8 7.5 110.4 7.4 12.5 124.9 15.7 80.3 19.1 178.4 40.0 26.8 143.0 130.2 211.1 9.4 8.6 108.4 29.3 164.8 25.5 15.5 10.9 107.3 46.4 16.8 14.5 67.0 14.2 49.0 20.6 0.6 55.8 70.9 30.4 66.9 52.7 88.7 13.1 130.9 68.9 35.6 12.7 21.8 79.5 36.0 15.7 117.5 93.3 7.5 0.0 1.6 0.2 0.0 457.1 234.6 22.5 202.0 202.5 5.8 4.5 4.7 0.0 0.0 4.2 394.6 0.6 0.1 9.8 1.0 1.0 0.0 2.3 0.4 4.7 0.0 74.2 0.0 0.1 216.6 0.4 3.9 14.1 2.8 10.4 0.1 0.0 0.1 25.3 0.4 0.5 0.5 0.5 0.0 0.5 0.4 30.2 0.2 1.2 0.1 0.2 0.1 12.3 0.7 2.6 7.0 2.9 0.3 1.9 3.2 6.6 3.8 0.1 0.1 0.0 0.2 0.4 0.0 0.0 6.6 0.1 2.2 0.8 0.2 0.5 0.0 0.3 0.1 0.0 0.1 1.1 1.8 2.5 0.0 0.2 0.0 0.1 0.4 10.7 12.8 7.4 12.5 9.4 8.6 15.5 10.9 14.2 13.1 12.7 7.5 31.4 83.3 13.1 0.0 2.1 9.2 2.4 7.1 1.8 0.0 11.2 9.3 5.2 0.0 11.5 5.5 0.0 2.5 2.5 0.1 5.9 4.7 5.9 13.3 67.4 15.2 0.0 0.4 2.6 4.7 2.5 209.4 2.0 12.0 2.5 1.8 34.2 0.4 7.8 0.0 3.6 0.1 18.3 2.5 18.4 27.5 626.6 5.8 21.4 15.9 1.6 0.0 8.2 5.0 2.3 2.2 0.0 794.8 0.7 1.3 0.0 32.5 21.4 0.0 6.6 28.0 14.5 3.0 2.8 1.3 8.7 3.7 15.5 3.5 0.4 1.2 FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 63.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 216.6;Leydig cells: 83.3;Proximal tubular cells: 53.4;Smooth muscle cells: 71.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 112.1;ASC TERT1: 66.1;BJ: 45.6;fHDF/TERT166: 50.3;HSkMC: 84.8;RH-30: 119.7;U-138 MG: 56.5" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" 43.8 4.5 3.4 31.5 3.9 0.1 8.5 4.2 5.2 29.4 2.1 11.1 3.7 29.2 4.3 9.5 15.4 46.0 10.5 3.3 4.8 4.5 1.4 12.9 8.3 4.6 4.6 13.4 2.2 3.6 2.2 23.5 5.1 16.2 9.6 8.4 5.1 12.0 2.2 2.6 3.6 26.9 4.1 1.8 5.5 2.3 4.5 3.0 7.4 23.8 4.8 63.3 10.3 4.5 0.2 0.0 0.2 0.3 112.1 66.1 0.1 45.6 25.7 0.0 0.1 0.0 0.3 0.2 0.2 50.3 0.4 0.9 0.0 0.3 0.0 0.1 0.2 0.0 0.5 0.0 10.6 0.3 0.1 84.8 0.8 9.4 0.0 0.3 0.0 0.0 0.1 0.3 5.4 0.1 0.0 0.1 0.2 0.1 0.3 0.1 119.7 0.1 0.1 0.1 1.8 0.6 0.4 0.0 0.4 0.2 0.2 0.2 0.2 56.5 0.5 1.1 0.2 0.5 0.4 0.0 13.3 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.9 4.2 5.2 3.3 4.8 4.6 4.6 5.1 4.1 4.5 4.5 16.1 12.8 19.3 2.0 2.2 14.4 16.8 1.3 1.2 7.9 11.1 9.5 46.8 7.2 0.5 9.2 2.1 6.2 3.2 0.2 119.3 2.0 3.3 8.8 46.2 5.2 0.0 2.7 1.9 0.6 3.3 216.6 2.0 29.2 1.3 0.6 1.8 2.7 2.0 3.3 3.3 0.0 2.0 1.6 15.9 4.0 83.3 1.9 7.2 1.0 0.2 9.8 2.1 1.5 2.9 0.6 0.0 4.9 0.7 9.4 0.0 53.4 0.3 6.1 6.6 43.6 71.6 0.6 0.7 1.8 12.6 2.9 2.9 2.9 0.1 8.4 FHL5 "ACT, dJ393D12.2, FLJ33049" ENSG00000112214 "Four and a half LIM domains 5" Q5TD97 6 96562548-96616636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.5" "Group enriched" "Detected in some" 20 "Early spermatids: 1160.3;Late spermatids: 1540.1" "Cancer enhanced" "Detected in many" "renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "ASC diff: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "prognostic favorable (4.81e-4)" "unprognostic (4.93e-2)" "unprognostic (1.91e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (6.56e-2)" "unprognostic (1.84e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-3)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.22e-1)" "unprognostic (3.48e-3)" 35.7 10.3 5.4 4.4 8.5 0.0 16.0 5.8 7.5 27.8 6.2 5.8 2.5 15.0 17.6 9.6 21.5 12.9 5.6 4.9 5.3 6.4 0.4 14.0 1.8 6.3 5.8 11.4 4.6 3.3 1.2 0.6 7.1 4.9 5.0 0.4 2.1 11.1 8.9 5.5 5.1 9.6 5.4 3.5 4.0 65.5 7.2 1.2 8.9 14.6 0.8 6.8 10.3 5.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 8.5 5.8 7.5 4.9 5.3 6.3 5.8 7.1 5.4 7.2 5.5 5.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1160.3 0.0 0.1 3.8 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1540.1 52.5 1.1 5.4 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.2 0.0 0.0 0.0 0.0 52.6 1.9 67.4 13.2 4.4 0.0 0.3 0.0 0.6 0.1 0.0 0.2 FIBIN MGC24932 ENSG00000176971 "Fin bud initiation factor homolog" Q8TAL6 11 26994112-26997087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 33.0;Fibroblasts: 80.8;Granulosa cells: 42.4;Leydig cells: 37.9;Oligodendrocyte precursor cells: 32.2;Peritubular cells: 35.0" "Cancer enhanced" "Detected in all" "glioma: 48.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 65.2;ASC TERT1: 41.8;fHDF/TERT166: 22.1;HHSteC: 88.2;HSkMC: 89.5;hTCEpi: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040120 Uncertain "Intracellular and membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA040120: AB_10795243" "unprognostic (1.72e-1)" "unprognostic (2.61e-1)" "unprognostic (1.29e-1)" "unprognostic (9.04e-2)" "unprognostic (1.62e-2)" "unprognostic (5.42e-2)" "unprognostic (7.28e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (5.08e-3)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "prognostic favorable (1.93e-5)" "prognostic unfavorable (6.72e-4)" "unprognostic (8.48e-2)" "prognostic unfavorable (1.85e-6)" "unprognostic (1.02e-2)" 32.3 4.9 11.0 7.7 10.6 0.0 25.1 11.4 10.8 35.6 6.1 27.8 2.2 26.1 8.0 11.3 35.7 7.9 32.6 10.8 10.7 15.2 2.0 27.2 2.8 10.6 12.7 18.5 3.8 0.3 2.6 12.6 11.7 17.0 2.6 0.6 17.6 61.3 17.1 16.7 12.0 17.1 11.4 14.1 21.1 1.3 11.6 2.1 13.4 14.5 0.9 16.3 58.3 11.7 0.0 0.0 1.0 0.0 65.2 41.8 0.1 2.1 5.7 0.2 0.9 0.0 0.0 0.0 0.0 22.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 88.2 0.0 0.0 89.5 24.0 1.1 0.0 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 4.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 10.6 11.4 10.8 10.8 10.7 10.6 12.7 11.7 11.4 11.6 11.7 2.5 0.0 0.0 17.9 0.0 6.6 1.6 33.0 1.8 0.3 1.9 0.9 1.2 11.5 4.0 11.0 0.0 1.2 0.0 0.1 11.7 0.6 0.1 0.0 0.1 1.0 0.0 0.0 0.5 0.0 0.9 80.8 0.0 0.0 0.0 42.4 6.1 0.5 1.8 0.0 0.1 0.0 12.2 0.0 10.3 0.3 37.9 0.8 7.2 0.0 0.0 19.8 0.0 32.2 0.1 0.1 0.0 35.0 0.1 0.2 0.0 4.3 0.9 0.6 0.0 3.7 7.4 0.1 0.3 0.8 5.1 1.9 0.5 3.9 0.0 0.0 FITM2 "C20orf142, dJ881L22.2, FIT2" ENSG00000197296 "Fat storage inducing transmembrane protein 2" Q8N6M3 20 44302840-44311202 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Deafness, Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 67.4" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 153.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.92e-2)" "unprognostic (7.61e-2)" "unprognostic (2.27e-2)" "unprognostic (2.10e-3)" "unprognostic (1.02e-1)" "unprognostic (3.57e-3)" "unprognostic (1.63e-2)" "unprognostic (3.90e-2)" "unprognostic (8.43e-2)" "unprognostic (5.19e-2)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "prognostic favorable (8.98e-12)" "unprognostic (2.07e-1)" "unprognostic (2.54e-1)" "unprognostic (3.38e-3)" "unprognostic (2.49e-3)" 11.4 11.1 4.8 2.9 5.0 1.2 7.0 5.7 6.3 4.2 5.9 5.2 4.3 4.0 8.7 3.3 3.7 3.2 67.4 4.8 5.9 7.9 6.4 4.1 2.2 6.9 5.9 4.6 7.4 13.6 5.2 1.9 7.4 6.4 6.0 6.7 6.5 4.4 9.2 5.7 3.9 5.3 4.2 2.6 4.6 3.8 5.4 1.7 6.3 16.8 2.6 4.5 3.1 4.7 7.2 10.9 4.5 6.6 31.4 12.8 4.6 11.5 8.4 8.9 4.9 13.5 5.1 4.9 6.5 13.0 14.3 15.8 5.7 7.7 9.6 1.4 2.7 1.6 6.5 22.9 6.6 3.1 4.0 9.7 17.2 6.2 4.7 4.9 6.4 3.1 2.7 14.2 9.1 22.4 1.2 3.4 1.1 10.8 13.9 1.9 8.4 4.9 5.1 6.7 2.7 3.2 24.4 13.5 10.3 2.0 16.5 2.4 7.9 28.2 12.6 16.6 6.8 5.2 14.4 1.3 12.6 4.9 14.4 0.7 1.0 0.6 1.1 1.0 1.2 0.6 1.2 0.9 1.0 0.6 2.0 1.6 0.4 1.4 0.8 0.6 1.2 0.9 4.8 5.0 5.7 6.3 4.8 5.9 6.9 5.9 7.4 4.2 5.4 4.7 2.8 6.4 9.7 1.3 3.6 6.9 3.5 2.8 1.2 6.4 5.0 3.4 153.9 11.5 4.3 5.5 6.2 2.0 1.0 5.1 1.9 5.2 4.6 2.2 5.0 4.4 9.1 0.8 2.3 8.6 3.5 9.4 4.1 2.1 0.0 4.4 8.2 14.1 3.4 6.7 2.1 4.8 0.0 3.8 2.2 1.2 7.8 1.7 7.2 1.0 2.3 6.6 2.1 4.0 0.9 5.7 4.1 7.5 3.1 3.1 5.9 6.2 4.0 5.9 0.0 5.6 6.3 9.1 6.0 2.7 8.1 1.5 2.1 16.3 9.2 2.2 FKBP14 "FKBP22, FLJ20731" ENSG00000106080 "FKBP prolyl isomerase 14" Q9NWM8 7 30010587-30026702 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Deafness, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013329, HPA026829" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" Cytosol "Nucleoplasm, Golgi apparatus" "HPA013329: AB_1848613, HPA026829: AB_10601651" "prognostic unfavorable (1.60e-4)" "unprognostic (1.12e-3)" "unprognostic (6.84e-2)" "unprognostic (1.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (6.06e-2)" "unprognostic (7.00e-2)" "unprognostic (6.99e-2)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-3)" "prognostic unfavorable (4.25e-4)" 6.5 5.1 3.4 7.0 3.5 4.3 6.4 5.4 3.6 9.9 3.1 4.7 3.0 8.5 10.0 4.7 4.3 6.0 6.8 3.2 3.2 3.1 3.2 4.1 3.1 3.3 3.1 5.4 5.8 6.2 7.7 7.9 3.0 6.8 4.8 7.2 4.3 7.5 2.1 4.7 2.9 13.9 3.0 2.7 4.0 2.2 3.5 1.8 3.3 3.2 3.2 8.9 3.8 3.5 7.0 5.2 14.4 33.6 36.8 46.8 6.5 34.9 32.7 12.0 23.3 4.4 4.3 2.4 16.0 31.0 14.7 14.8 8.1 12.8 23.9 1.3 11.6 5.6 9.2 13.1 18.6 4.0 9.3 29.4 13.1 20.9 24.6 28.2 27.0 3.6 9.2 5.0 21.8 2.9 2.1 4.9 7.5 7.7 9.2 0.1 9.6 8.2 11.8 6.1 3.8 12.5 12.2 27.5 8.8 17.0 6.2 5.3 21.7 12.6 14.6 21.8 14.0 7.6 8.3 4.2 18.0 3.8 40.2 0.5 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.4 0.2 0.0 0.6 0.2 0.1 3.4 3.5 5.4 3.6 3.2 3.2 3.3 3.1 3.0 3.0 3.5 3.5 13.5 19.2 16.0 7.2 7.9 27.4 22.0 15.8 35.9 16.3 13.3 13.0 15.7 5.7 11.7 18.4 27.1 11.6 9.4 5.3 1.9 7.4 0.4 30.4 44.3 12.9 1.2 6.5 19.4 3.7 27.3 40.0 15.3 40.0 2.5 9.1 8.6 6.5 6.0 15.2 12.7 9.7 8.2 2.5 11.2 0.4 13.1 5.7 10.6 10.3 3.6 26.5 2.1 11.6 16.6 5.7 19.0 20.7 43.8 17.8 3.3 2.7 6.0 21.4 6.6 13.8 20.4 1.4 3.4 27.5 18.3 15.7 6.0 20.8 6.1 28.0 FKBP5 "FKBP51, FKBP54, P54, PPIase, Ptg-10" ENSG00000096060 "FKBP prolyl isomerase 5" Q13451 6 35573585-35728583 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 892.7;tongue: 925.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 759.3;ASC TERT1: 468.5;HHSteC: 593.0;HSkMC: 718.3;hTCEpi: 368.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009315, HPA031092, HPA031093, HPA031095" Enhanced Enhanced Nucleoplasm No No 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB009315: AB_2278350, HPA031092: AB_10600195, HPA031093: AB_10601748, HPA031095: AB_2673734" "unprognostic (2.09e-3)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.72e-1)" "unprognostic (6.30e-3)" "unprognostic (3.70e-3)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (7.48e-3)" "unprognostic (2.18e-3)" "unprognostic (8.31e-2)" "unprognostic (4.22e-2)" "unprognostic (6.90e-3)" 400.1 92.3 18.2 70.1 26.8 26.6 160.4 19.7 32.1 86.4 20.2 110.9 11.3 97.5 63.0 130.6 104.6 78.9 93.7 16.8 20.7 108.8 144.5 92.7 166.7 22.7 23.8 122.1 200.4 227.0 52.9 28.5 23.5 85.0 37.1 25.6 61.0 49.8 892.7 114.0 135.7 81.8 17.0 105.6 129.0 41.4 22.1 229.4 97.2 925.1 80.3 108.9 109.1 26.2 40.0 17.1 73.1 109.7 759.3 468.5 1.2 21.2 1.0 13.6 31.0 29.7 6.9 195.3 19.5 4.1 11.8 0.6 44.1 93.2 32.0 77.7 41.6 84.0 14.1 41.7 593.0 53.3 8.3 718.3 368.6 23.7 220.5 14.8 80.1 38.8 91.3 77.1 144.3 25.3 222.5 99.6 18.9 8.7 12.3 97.7 19.1 95.4 60.2 23.7 27.7 16.8 17.3 19.8 4.2 15.9 108.4 62.2 178.7 19.3 17.3 2.8 29.7 34.9 42.9 243.5 6.6 102.3 7.6 57.6 105.0 70.0 64.4 92.3 78.0 9.7 90.6 68.5 107.5 12.5 133.4 96.7 85.1 45.2 46.8 32.0 37.2 158.5 18.2 26.8 19.7 32.1 16.8 20.7 22.7 23.8 23.5 17.0 22.1 26.2 180.2 12.8 11.3 23.2 42.9 17.6 59.2 20.1 37.0 1.9 32.0 20.8 131.8 74.4 14.2 5.5 0.0 1.2 102.0 14.3 23.5 0.6 9.8 55.7 76.1 57.9 20.9 102.2 25.9 7.9 0.8 97.5 18.8 79.2 38.5 54.7 117.1 225.6 35.1 0.0 2.8 35.5 34.6 384.2 44.8 22.0 160.9 192.2 7.2 66.5 110.3 4.6 44.3 16.6 26.3 2.9 19.3 218.6 66.4 49.9 157.0 27.4 18.2 22.6 144.7 188.1 106.8 14.9 19.1 37.5 21.3 0.4 128.7 2.8 39.5 22.2 FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 149.1;Endometrial stromal cells: 54.8;Fibroblasts: 67.6;Leydig cells: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 155.0;ASC TERT1: 96.7;fHDF/TERT166: 60.9;HSkMC: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.3 5.4 1.5 3.9 1.6 1.4 11.9 2.6 2.8 23.1 1.5 8.3 2.8 27.8 11.3 5.9 15.1 15.4 12.3 1.6 1.8 5.2 8.3 7.8 2.9 1.6 1.5 50.0 2.8 2.7 5.0 13.0 1.5 9.3 6.2 2.1 5.0 13.3 3.8 4.2 4.4 19.2 1.2 3.0 5.4 4.4 1.5 2.5 6.6 6.5 2.8 11.6 10.2 2.1 0.2 1.9 18.5 27.8 155.0 96.7 1.7 33.3 55.0 5.9 19.0 0.3 1.9 5.4 7.3 60.9 5.5 0.3 7.1 2.8 10.3 4.5 3.9 5.7 7.3 5.5 23.7 3.5 3.8 64.7 1.4 24.0 3.4 44.2 19.8 6.6 2.5 3.4 25.2 0.3 6.1 6.0 3.6 3.5 2.9 7.8 31.9 7.7 8.4 0.6 9.7 32.0 7.0 0.2 6.2 12.7 0.5 6.8 18.2 11.0 6.8 12.8 3.2 6.3 7.2 2.6 19.9 8.7 24.3 0.0 0.4 0.0 1.0 0.7 1.2 1.1 0.9 0.7 2.6 0.7 0.9 1.0 0.0 0.6 0.0 2.1 1.1 0.4 1.5 1.6 2.6 2.8 1.6 1.8 1.6 1.5 1.5 1.2 1.5 2.1 16.2 6.4 4.1 2.9 5.4 7.0 9.3 19.6 7.4 4.2 6.7 13.6 16.1 2.8 5.2 7.3 0.0 7.6 2.7 0.7 1.9 10.9 149.1 3.4 54.8 19.3 1.2 4.2 1.6 8.4 22.4 67.6 4.1 3.5 14.0 19.0 15.7 11.9 5.8 5.0 3.7 5.6 14.2 4.4 13.6 27.1 64.0 3.8 17.8 4.7 1.6 4.2 1.0 7.1 4.2 3.9 0.7 48.5 10.3 3.4 0.4 3.7 2.1 3.6 6.6 31.1 37.7 8.5 5.1 3.7 5.8 5.1 5.5 30.4 3.1 4.1 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FMO1 ENSG00000010932 "Flavin containing dimethylaniline monoxygenase 1" Q01740 1 171248471-171285978 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "kidney: 199.0" "Group enriched" "Detected in many" 7 "Proximal enterocytes: 97.9;Proximal tubular cells: 196.9" "Cancer enriched" "Detected in many" 8 "renal cancer: 18.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HSkMC: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078132 Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA078132: " "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (5.87e-2)" "unprognostic (1.34e-1)" "unprognostic (5.32e-3)" "unprognostic (1.89e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-1)" "unprognostic (9.16e-2)" "unprognostic (9.03e-2)" "unprognostic (1.36e-2)" "unprognostic (2.23e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.49e-4)" "unprognostic (1.40e-1)" "unprognostic (3.58e-1)" "unprognostic (1.37e-1)" 5.1 5.6 0.1 0.5 0.1 0.0 10.0 0.1 0.3 6.3 0.3 0.4 0.1 3.1 0.1 3.5 4.2 5.2 0.7 0.1 0.1 199.0 2.9 1.5 0.4 0.1 0.1 5.0 2.4 1.1 1.8 2.3 0.1 0.4 0.2 0.0 5.4 0.7 0.1 10.4 20.2 4.2 0.1 0.0 0.9 1.6 0.1 7.4 2.3 0.8 10.8 2.5 1.7 0.1 0.0 0.0 0.0 0.0 2.7 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 5.0 0.0 0.0 0.3 3.0 3.2 0.5 0.0 12.5 0.0 0.5 1.1 10.0 2.8 0.0 3.7 0.0 0.3 0.0 0.0 13.7 0.0 0.7 0.0 0.1 1.1 0.0 0.0 0.1 0.0 0.1 18.7 0.0 0.0 0.0 3.2 0.0 0.3 0.4 0.0 0.1 2.9 0.0 0.0 0.0 1.5 10.8 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.8 2.6 0.0 0.1 97.9 196.9 0.0 0.0 6.6 0.5 4.7 0.0 0.1 1.4 2.3 0.8 1.0 2.6 1.4 0.1 FMO2 ENSG00000094963 "Flavin containing dimethylaniline monoxygenase 2" Q99518 1 171185249-171212686 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 69.7;lung: 93.9" "Cell type enhanced" "Detected in many" "Adipocytes: 187.0;Alveolar cells type 1: 461.6;Club cells: 204.7;Fibroblasts: 98.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 57 "ASC diff: 30.6;ASC TERT1: 13.7;HSkMC: 37.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028261 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA028261: AB_10601012" "unprognostic (1.85e-2)" "unprognostic (3.14e-2)" "unprognostic (7.44e-2)" "unprognostic (3.75e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-2)" "unprognostic (1.66e-3)" "unprognostic (3.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.58e-2)" "unprognostic (1.16e-1)" "unprognostic (4.28e-1)" "unprognostic (1.53e-1)" "unprognostic (1.26e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (3.83e-2)" 69.7 24.0 1.5 1.3 2.4 0.1 47.8 1.3 1.4 6.6 2.9 6.5 0.9 5.1 7.7 65.9 33.3 4.6 50.0 0.8 4.1 10.4 4.3 93.9 11.6 2.2 1.7 4.3 5.5 4.9 6.3 0.3 1.7 5.5 1.7 0.9 36.5 2.9 17.6 4.5 4.2 3.9 1.5 0.7 6.8 1.1 4.7 8.6 12.0 20.3 11.8 4.5 11.6 1.1 0.0 0.0 0.0 0.0 30.6 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 37.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.4 1.3 1.4 0.8 4.1 2.2 1.7 1.7 1.5 4.7 1.1 187.0 461.6 21.7 2.6 0.1 0.4 4.4 36.0 2.8 0.4 14.5 69.1 9.2 0.0 204.7 1.8 0.0 0.0 0.5 0.0 0.0 0.5 5.5 0.1 0.1 69.1 0.0 0.0 0.1 0.0 0.0 98.7 0.0 0.0 3.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.7 2.8 0.9 1.8 0.0 37.5 0.0 0.2 0.0 2.0 0.1 1.3 0.0 0.0 2.5 3.7 0.0 10.2 36.0 0.6 0.0 9.7 48.5 0.3 0.1 7.4 0.0 0.0 1.1 1.6 0.0 1.2 FMO3 FMOII ENSG00000007933 "Flavin containing dimethylaniline monoxygenase 3" P31513 1 171090901-171117819 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1123.3" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 412.3" "Cancer enriched" "Detected in many" 13 "liver cancer: 94.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 34.6;ASC TERT1: 26.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA013750 Enhanced NA NA "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA013750: AB_1848968" "unprognostic (1.87e-2)" "unprognostic (6.30e-2)" "unprognostic (1.00e-1)" "unprognostic (6.81e-3)" "unprognostic (2.64e-1)" "unprognostic (1.31e-3)" "prognostic favorable (3.46e-4)" "prognostic favorable (5.60e-5)" "unprognostic (2.95e-1)" "unprognostic (9.34e-2)" "unprognostic (3.02e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (3.45e-1)" "unprognostic (7.27e-2)" 27.2 12.4 2.5 0.9 2.7 0.4 6.8 2.5 3.6 1.2 2.3 1.4 1.8 1.3 3.0 5.1 13.3 1.8 4.2 2.3 2.6 14.0 1123.3 18.7 4.9 5.0 2.7 0.3 4.5 4.2 4.3 0.2 3.1 1.1 0.7 0.1 5.1 0.4 4.6 4.3 2.2 1.6 4.0 0.4 3.9 0.5 2.8 1.4 2.6 3.1 9.1 1.0 0.9 2.6 0.0 0.0 0.0 0.0 34.6 26.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.0 7.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.7 2.5 3.6 2.3 2.6 5.0 2.7 3.1 4.0 2.8 2.6 2.7 12.8 0.5 0.0 0.7 0.4 0.4 2.7 0.0 0.0 0.1 0.3 0.4 7.2 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.2 0.0 4.7 0.0 29.5 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 6.8 412.3 0.0 0.0 0.0 0.0 4.1 9.5 0.8 0.0 0.3 0.1 1.8 1.0 0.0 0.5 0.0 7.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 22.7 0.2 6.6 1.3 6.3 0.4 0.1 0.4 0.4 0.0 0.8 0.2 0.0 0.1 FMO4 FMO2 ENSG00000076258 "Flavin containing dimethylaniline monoxygenase 4" P31512 1 171314183-171342084 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 48.6;liver: 61.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Hepatocytes: 22.1;Oligodendrocytes: 18.5;Proximal enterocytes: 16.5;Proximal tubular cells: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 5.7;HSkMC: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049100, HPA072438" Approved Approved Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "HPA049100: AB_2680629, HPA072438: " "unprognostic (1.83e-2)" "unprognostic (1.17e-1)" "unprognostic (6.18e-2)" "unprognostic (3.01e-2)" "unprognostic (8.27e-2)" "unprognostic (4.13e-1)" "prognostic favorable (1.09e-4)" "prognostic favorable (7.45e-4)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (5.99e-2)" "unprognostic (2.90e-1)" "prognostic favorable (6.96e-4)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (7.45e-3)" "unprognostic (1.95e-1)" 3.7 2.6 2.2 1.9 3.1 0.9 4.1 2.8 3.0 3.3 3.1 5.0 5.4 2.7 6.3 2.3 3.5 4.9 5.2 2.1 2.6 48.6 61.3 3.2 2.9 3.1 2.8 3.8 2.4 4.7 1.9 2.3 3.3 3.1 4.8 0.7 2.0 2.2 1.0 3.4 9.2 2.0 2.6 3.1 5.0 1.7 3.1 3.6 3.2 2.1 3.3 2.4 2.9 3.5 0.1 0.1 0.3 0.4 4.1 3.4 0.2 0.8 3.7 1.1 1.2 0.6 5.3 3.7 5.7 0.1 2.0 0.2 0.7 1.0 1.6 1.6 0.8 0.0 0.0 0.0 0.6 0.7 0.8 6.6 2.4 0.4 1.0 0.4 0.2 1.7 0.2 2.3 0.5 0.7 1.6 1.3 0.4 0.9 1.2 0.4 0.4 2.1 2.6 0.0 0.1 0.0 1.2 1.0 2.4 4.1 2.2 1.0 0.1 0.9 0.3 1.0 0.7 2.9 1.0 2.2 1.8 1.1 0.8 0.2 1.0 0.3 0.9 1.6 0.7 1.2 0.8 1.3 0.9 1.8 1.2 0.9 0.1 1.7 1.1 1.2 2.1 0.8 2.2 3.1 2.8 3.0 2.1 2.6 3.1 2.8 3.3 2.6 3.1 3.5 2.2 0.0 2.6 7.2 3.2 2.8 4.6 5.0 2.8 0.0 2.3 2.0 3.7 2.8 3.7 9.2 0.0 2.8 0.6 7.1 29.4 2.3 5.7 3.8 1.7 1.4 1.2 0.0 0.1 1.4 1.2 6.6 8.2 1.7 1.3 1.5 2.9 22.1 3.7 0.0 0.1 3.2 2.0 5.9 1.3 1.3 1.5 2.7 5.4 2.8 1.6 1.8 1.0 0.0 18.5 1.1 0.7 0.4 1.1 0.9 16.5 49.5 7.3 0.0 0.0 1.8 2.1 0.3 0.5 1.9 1.6 1.9 1.7 2.0 2.8 1.8 FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2583.6;Fibroblasts: 562.6;Hepatocytes: 1012.4;Smooth muscle cells: 450.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 34405.9;HSkMC: 16044.5;hTERT-HME1: 9585.3;hTERT-RPE1: 10587.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" 151.1 31.4 37.8 131.9 44.8 0.6 76.5 36.3 51.2 135.9 85.9 444.0 33.8 156.1 61.3 251.6 174.5 187.1 410.9 38.9 41.1 42.9 1725.9 785.7 37.3 37.7 39.8 110.0 26.0 19.3 26.2 2928.1 43.5 105.6 237.2 6.0 67.0 428.9 37.7 52.7 103.4 722.6 36.2 14.3 127.2 25.8 112.1 133.8 40.4 148.4 23.9 361.7 87.1 35.3 12.5 84.2 104.6 22.8 4456.5 34405.9 4.8 1799.2 1200.2 1765.3 1259.9 1059.2 43.7 1.2 9.7 6331.7 47.2 192.7 17.4 4220.9 946.9 1.0 7.4 0.8 24.7 3607.2 3192.2 1.2 6.6 16044.5 29.3 4136.5 9585.3 10587.1 2177.2 1.0 8.2 5.0 3673.9 17.0 2.9 1.5 52.7 2.4 15.2 1.0 2.4 8.0 47.4 13.7 6.0 25.0 213.7 116.4 1219.8 4649.5 19.4 3.2 4161.0 2553.1 269.9 2837.4 355.6 4.4 1.6 1.6 3161.2 1.0 694.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.8 44.8 36.3 51.2 38.9 41.1 37.7 39.8 43.5 36.2 112.1 35.3 138.9 67.3 67.8 13.4 2.3 55.1 4.1 227.0 2.2 6.4 4.2 5.2 36.3 30.0 34.0 16.5 0.0 216.6 2.3 3.4 0.0 6.5 1.8 6.5 265.8 215.4 21.0 16.8 9.5 9.8 2583.6 562.6 4.1 5.5 18.9 53.5 227.7 1012.4 365.2 1.7 8.1 10.2 12.2 38.0 73.7 4.6 186.4 85.9 110.3 101.2 1.2 1.9 0.0 11.6 10.7 12.5 1.4 88.4 1.7 17.8 0.0 0.6 23.1 8.7 72.3 401.5 450.2 1.6 7.8 5.0 37.4 205.8 11.3 8.5 23.7 1.7 FOXO1 "FKH1, FKHR, FOXO1A" ENSG00000150907 "Forkhead box O1" Q12778 13 40555667-40666641 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Autophagy, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.0" "Cell type enhanced" "Detected in many" "Astrocytes: 177.3;Endometrial stromal cells: 161.0;Granulosa cells: 177.9;Oligodendrocytes: 131.5;Skeletal myocytes: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 40.4;Daudi: 45.3;HSkMC: 53.6;U-698: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001252, CAB022326" Approved Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "CAB022326: , HPA001252: AB_1078906" "unprognostic (4.72e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-2)" "unprognostic (4.35e-1)" "unprognostic (2.42e-1)" "unprognostic (2.52e-1)" "prognostic favorable (3.74e-4)" "unprognostic (6.35e-2)" "unprognostic (1.60e-1)" "unprognostic (8.65e-3)" "unprognostic (1.71e-1)" "unprognostic (1.31e-1)" "prognostic favorable (1.33e-5)" "unprognostic (1.93e-1)" "unprognostic (5.44e-1)" "unprognostic (9.09e-2)" "unprognostic (9.63e-2)" 43.2 9.7 11.2 13.1 16.1 13.8 27.6 10.0 10.9 19.1 16.7 13.8 5.0 39.1 6.5 13.0 25.7 14.5 13.9 9.1 11.8 11.8 38.5 16.8 23.8 14.1 12.7 65.6 16.5 5.3 7.6 11.2 12.7 10.1 9.6 3.9 9.8 10.1 91.0 18.0 10.9 27.0 10.5 15.7 9.5 8.9 11.3 11.6 19.0 22.2 24.0 13.4 17.4 14.3 0.7 1.7 12.4 0.3 40.4 7.9 11.8 1.8 2.5 0.5 0.3 3.7 3.0 45.3 8.1 1.2 1.9 10.7 9.8 5.3 0.7 20.9 10.1 0.0 1.4 10.1 19.1 0.4 1.2 53.6 35.5 0.2 6.7 2.5 31.7 3.3 0.9 14.0 3.1 1.6 0.1 0.6 18.0 6.2 3.1 32.4 14.3 3.6 22.9 5.8 2.6 0.6 1.6 8.5 1.8 14.1 1.5 1.1 18.6 0.3 2.3 0.1 1.1 7.9 3.3 57.8 1.2 2.1 5.7 0.9 0.6 0.5 1.3 0.8 1.8 3.7 3.6 2.2 0.4 5.8 5.5 4.3 2.5 1.4 1.4 0.0 5.1 1.0 11.2 16.1 10.0 10.9 9.1 11.8 14.1 12.7 12.7 10.5 11.3 14.3 57.9 0.0 4.4 177.3 29.3 29.3 19.1 13.0 27.9 3.7 12.9 17.3 11.5 10.0 9.9 9.2 12.5 0.5 22.9 27.5 0.0 11.1 7.2 55.4 161.0 50.2 52.2 3.2 7.4 18.0 3.8 40.8 18.8 118.8 1.3 177.9 84.3 47.9 6.5 5.0 23.0 21.0 8.2 14.6 26.9 4.0 18.6 18.6 12.4 117.1 18.4 5.5 8.2 47.3 131.5 19.5 16.3 13.2 32.9 10.1 7.7 8.8 9.2 9.8 6.6 131.7 31.3 6.4 14.6 25.3 26.7 0.8 40.3 64.0 12.5 13.0 FTH1 "FHC, FTH, FTHL6, PIG15, PLIF" ENSG00000167996 "Ferritin heavy chain 1" P02794 11 61959718-61967634 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Iron storage" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 49889.9;monocytes: 34409.9;Proximal enterocytes: 28837.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 23933.9;HHSteC: 24849.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008623 Approved NA NA 5600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "CAB008623: " "unprognostic (7.15e-2)" "unprognostic (1.52e-2)" "unprognostic (2.27e-1)" "unprognostic (2.00e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (7.56e-5)" "prognostic unfavorable (6.18e-4)" "unprognostic (3.08e-2)" "unprognostic (2.48e-2)" "unprognostic (6.65e-2)" "unprognostic (2.44e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (5.20e-5)" "unprognostic (2.99e-1)" "unprognostic (4.89e-2)" "unprognostic (3.44e-1)" "unprognostic (5.83e-2)" 6767.7 5191.4 5741.8 3546.9 5464.0 4734.2 5696.1 5591.9 7973.3 3973.1 4801.2 4701.2 1819.9 3712.8 2421.8 4025.0 3195.6 1995.6 4779.5 5252.8 5737.2 6092.3 3500.8 6057.7 1460.4 6416.7 5812.4 3069.9 3883.8 1696.4 2105.4 1800.3 6188.9 2778.8 3357.4 3123.7 3533.1 1514.8 4695.5 2125.0 4331.6 2040.7 6506.2 3496.3 4044.1 769.5 6153.5 1109.8 3167.6 2766.8 1291.2 4718.0 3163.8 6630.2 3029.8 8290.2 1236.6 3293.8 23933.9 11490.1 6794.4 2684.1 11547.3 2694.6 2698.6 1011.0 4065.8 345.3 16669.6 7830.0 10259.7 5035.8 1118.8 2235.9 1733.9 1439.0 542.9 1720.3 10802.1 6692.1 24849.2 821.6 2626.6 15711.1 10758.7 5384.0 10038.1 8476.6 3427.6 1970.7 2622.1 3874.4 9546.5 4080.7 935.3 1361.8 2114.6 10461.4 13675.6 914.9 1508.5 2502.3 13877.6 8068.8 1044.8 1325.0 9113.3 1005.9 4645.6 4045.3 1790.3 1098.4 3791.5 8310.7 1978.7 3727.4 1732.0 662.7 2516.5 1088.1 11353.7 363.1 2030.4 29466.0 19068.5 15453.6 2306.3 22407.8 2274.9 4088.8 3267.1 2296.9 9762.5 4113.3 2710.5 2108.2 45110.1 1981.1 27515.2 7217.1 4321.5 22214.4 5741.8 5464.0 5591.9 7973.3 5252.8 5737.2 6416.7 5812.4 6188.9 6506.2 6153.5 6630.2 3864.7 1317.3 2890.3 319.3 3200.9 5157.7 7723.2 23426.3 3495.0 881.7 9884.9 10192.4 11.7 4466.7 11711.1 1918.2 573.4 4541.1 4513.5 13653.9 10888.0 10748.7 274.2 4921.8 2908.5 4303.3 2520.6 6318.6 252.8 11073.9 6803.9 5931.3 2059.7 8005.0 6736.0 1798.6 3266.1 5199.9 18411.3 738.6 153.7 3927.4 10379.8 13784.1 49889.9 527.7 4666.1 22792.0 7116.5 183.6 34409.9 12189.1 1699.3 153.3 1031.0 7813.2 7936.8 3818.1 1789.1 12995.8 28837.7 21355.6 5978.6 3311.6 2084.0 2686.9 6139.1 585.4 927.1 1983.6 3555.6 4622.6 5225.4 2496.8 4921.7 18650.3 FTL "MGC71996, NBIA3" ENSG00000087086 "Ferritin light chain" P02792 19 48965309-48966879 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Iron storage" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 14422.9" "Cell type enhanced" "Detected in all" "Hofbauer cells: 74983.4;Kupffer cells: 70127.1;Macrophages: 34584.5;Proximal tubular cells: 58047.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 125209.0;monocytes: 102128.9" "Cell line enhanced" "Detected in all" "HHSteC: 24796.9;HSkMC: 20811.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020769, HPA041602" Enhanced Approved Cytosol NA NA 170000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB020769: , HPA041602: AB_2677575" "unprognostic (2.95e-1)" "unprognostic (2.64e-2)" "unprognostic (1.31e-1)" "unprognostic (1.56e-3)" "unprognostic (7.48e-2)" "unprognostic (5.28e-2)" "unprognostic (2.16e-3)" "unprognostic (6.17e-3)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (2.66e-1)" "unprognostic (2.96e-1)" "prognostic unfavorable (4.40e-5)" "unprognostic (1.32e-1)" "unprognostic (2.43e-2)" "unprognostic (2.30e-2)" "unprognostic (1.87e-2)" 6778.7 3262.2 6806.2 2353.2 7172.4 4213.8 4226.0 6782.1 10053.2 2094.3 6429.7 2451.1 2427.0 1523.4 1010.8 1306.2 2169.9 4298.0 2537.3 6497.7 6998.4 8845.6 14422.9 7261.1 3353.2 7250.8 6998.4 2455.3 2166.2 931.7 1730.4 3423.2 7218.5 1946.5 1800.0 684.9 1663.5 1390.4 1345.9 1449.7 2806.6 1842.3 7149.5 6751.4 3204.5 455.9 7581.8 1168.9 3000.4 1072.0 1334.6 4239.9 1804.7 7334.0 869.7 12906.5 949.6 1457.0 16013.9 16478.6 1693.1 2194.1 12820.0 3090.7 6903.8 2852.3 3413.2 656.4 4104.3 13203.9 6755.6 505.8 788.2 1301.8 2765.6 8895.0 507.6 1740.0 3222.8 18949.7 24796.9 4133.3 5591.2 20811.1 1735.9 5272.5 2301.6 4590.4 4549.8 774.6 3284.9 1328.2 6198.4 213.0 1152.1 2402.8 1729.8 15140.6 1306.9 947.6 643.0 6763.9 1989.7 545.0 1209.9 701.5 5761.7 313.4 1239.5 5104.1 183.2 8493.4 3438.3 3353.4 1740.1 4364.3 3083.1 5690.2 13742.1 625.1 3563.9 4334.7 6017.7 64938.4 71067.8 77353.0 6560.6 102128.9 7527.7 17097.3 7247.4 7054.3 25176.6 15607.2 8656.4 7466.9 125209.0 4978.3 91398.0 10579.6 9634.4 94147.5 6806.2 7172.4 6782.1 10053.2 6497.7 6998.4 7250.8 6998.4 7218.5 7149.5 7581.8 7334.0 2757.2 1125.0 3379.9 88.5 3311.5 2793.9 6799.5 2785.4 2159.8 474.7 2597.9 3977.3 777.8 4398.0 2550.4 2021.2 177.2 941.5 2199.4 2314.2 10704.0 4251.2 290.2 504.9 1413.1 4867.0 1613.4 4331.2 60.6 6134.8 1447.8 5703.3 1715.1 617.4 2365.7 942.2 4598.0 23702.0 74983.4 533.3 113.8 2368.8 3039.4 70127.1 16939.0 1601.8 4175.9 34584.5 5085.3 129.3 22965.8 3161.9 2020.6 55.8 309.7 6905.5 5604.7 2010.8 4884.7 9790.5 21474.5 58047.8 1908.0 682.6 1341.1 1643.8 3455.6 82.1 311.2 1985.5 2226.7 1502.7 2590.4 1492.0 2816.8 13083.6 FTO "ALKBH9, KIAA1752, MGC5149" ENSG00000140718 "FTO alpha-ketoglutarate dependent dioxygenase" Q9C0B1 16 53701692-54158512 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 173.3;Excitatory neurons: 226.1;Inhibitory neurons: 240.7;Oligodendrocyte precursor cells: 210.6;Oligodendrocytes: 282.5;Respiratory ciliated cells: 182.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017123, HPA041086, HPA068695" Enhanced Supported Vesicles,Cytosol No No 540000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Vesicles "CAB017123: , HPA041086: AB_2677293, HPA068695: AB_2732117" "unprognostic (9.74e-2)" "unprognostic (2.49e-1)" "unprognostic (9.30e-2)" "unprognostic (1.24e-2)" "unprognostic (1.81e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (1.41e-1)" "unprognostic (8.67e-2)" "unprognostic (1.02e-1)" "unprognostic (3.88e-2)" "unprognostic (6.80e-2)" "unprognostic (1.44e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-1)" "unprognostic (4.30e-3)" "unprognostic (6.11e-3)" 24.4 33.6 31.8 12.5 36.6 8.2 36.3 30.1 37.7 25.8 31.0 22.2 7.7 26.9 21.4 17.2 25.3 21.6 27.1 35.2 39.5 25.0 17.4 36.8 15.0 29.2 31.3 27.2 20.7 40.6 26.2 20.1 31.9 20.0 14.1 38.4 18.9 23.9 33.1 21.4 12.5 29.9 30.5 16.4 15.0 8.3 33.8 17.0 27.5 23.0 14.8 21.9 18.5 43.9 15.1 26.8 35.0 35.9 67.3 50.4 11.5 35.6 32.2 29.3 8.5 16.8 19.3 34.4 38.2 46.3 16.6 21.7 32.4 34.9 42.5 16.0 25.5 15.5 33.6 31.7 46.2 12.5 17.1 55.9 36.5 26.6 32.5 36.6 44.1 25.1 15.2 8.4 48.1 11.8 28.0 19.2 18.1 15.5 17.5 42.2 52.9 32.3 44.6 12.3 43.0 29.7 40.4 23.6 10.8 33.7 31.1 29.3 42.4 36.4 23.9 19.8 22.1 15.9 13.9 35.0 33.9 22.9 28.7 14.9 17.9 9.7 25.6 22.7 32.4 17.6 24.4 25.9 23.8 17.4 22.5 24.4 2.9 26.4 16.5 9.5 26.6 23.1 31.8 36.6 30.1 37.7 35.2 39.5 29.2 31.3 31.9 30.5 33.8 43.9 15.1 80.1 62.0 173.3 10.3 12.4 10.0 8.6 13.6 22.8 69.1 39.5 22.3 15.7 54.4 7.3 12.5 9.3 10.2 4.8 7.9 9.0 39.1 11.0 18.3 17.4 6.6 9.7 226.1 5.7 7.4 23.1 9.7 9.9 25.9 16.8 11.0 13.8 9.2 16.8 240.7 6.6 10.2 9.0 13.2 69.9 14.3 11.8 10.6 134.0 5.5 19.6 10.3 210.6 282.5 5.5 5.0 15.1 18.7 6.0 4.5 15.8 182.7 14.1 13.1 21.6 16.8 3.5 3.4 11.0 9.1 5.1 12.9 17.8 6.3 7.9 FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1381.3;tongue: 838.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 225.1;Hepatocytes: 651.7;Leydig cells: 430.3;Muller glia cells: 343.4;Skeletal myocytes: 188.7;Smooth muscle cells: 205.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.0" "Group enriched" "Detected in many" 4 "B-cells: 11.0;T-cells: 6.9" "Cell line enhanced" "Detected in some" "ASC diff: 46.7;ASC TERT1: 13.5;HSkMC: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" Nucleoli "HPA026873: AB_1855471" "unprognostic (5.58e-3)" "unprognostic (6.60e-2)" "unprognostic (3.37e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.91e-4)" "unprognostic (1.54e-2)" "unprognostic (1.72e-2)" "unprognostic (3.54e-3)" "unprognostic (8.13e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.59e-8)" "unprognostic (9.97e-3)" "unprognostic (2.25e-1)" "unprognostic (1.65e-1)" "unprognostic (1.92e-2)" 141.4 26.1 496.5 9.6 528.9 2.2 125.1 506.1 637.3 291.9 616.5 168.3 14.3 173.3 62.1 70.7 187.3 56.3 557.7 487.5 503.4 28.6 558.7 85.8 6.6 568.0 515.0 144.7 19.2 3.8 39.8 29.3 494.8 116.0 25.6 35.9 37.2 73.5 1381.3 48.3 67.2 104.5 511.1 20.8 72.6 12.1 560.2 8.2 38.0 838.7 6.7 80.0 194.9 498.6 1.1 0.0 0.0 0.2 46.7 13.5 1.3 5.7 0.1 0.0 0.0 0.0 0.3 3.8 1.5 0.0 0.1 1.0 1.1 0.7 0.0 3.4 1.3 0.7 0.0 1.9 5.2 0.3 0.4 19.3 0.0 0.1 0.5 0.5 0.2 0.1 1.0 3.7 0.1 0.0 0.1 0.8 0.2 2.8 0.6 0.0 0.2 1.1 0.0 0.0 0.3 0.2 0.7 0.2 1.8 0.3 0.2 6.1 0.5 0.1 0.5 0.4 0.0 0.1 0.0 0.4 0.9 0.6 7.7 1.6 0.3 0.0 1.3 0.7 0.8 11.0 3.6 1.5 0.3 6.9 0.7 0.9 0.5 2.1 0.8 0.6 6.9 0.6 496.5 528.9 506.1 637.3 487.5 503.4 568.0 515.0 494.8 511.1 560.2 498.6 46.1 0.0 0.0 44.4 15.8 29.4 3.7 2.7 8.0 1.8 4.4 18.0 0.3 11.5 0.8 25.8 4.2 1.2 9.5 42.2 0.0 0.1 1.9 2.2 47.4 13.3 0.0 8.4 3.7 4.9 1.6 225.1 2.0 1.2 0.0 0.1 36.0 651.7 4.4 0.0 0.4 0.8 2.0 14.4 49.0 12.0 430.3 5.3 53.4 2.8 1.0 343.4 1.0 1.5 0.5 1.1 5.3 128.2 2.5 3.3 0.4 0.2 12.6 8.6 118.3 188.7 205.7 10.7 21.7 3.0 27.3 2.9 18.8 0.1 0.7 2.5 FZD1 DKFZp564G072 ENSG00000157240 "Frizzled class receptor 1" Q9UP38 7 91264433-91271326 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 44.9;Cholangiocytes: 45.8;Horizontal cells: 141.3;Peritubular cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.0;non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 5 "monocytes: 2.8" "Cell line enhanced" "Detected in many" "AF22: 24.8;HSkMC: 32.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013008 Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB013008: " "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (4.51e-3)" "unprognostic (2.09e-1)" "unprognostic (5.29e-3)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (5.48e-3)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "prognostic favorable (8.87e-7)" "unprognostic (1.05e-2)" "unprognostic (4.16e-2)" "unprognostic (5.53e-2)" "unprognostic (4.13e-2)" 5.4 4.4 2.4 2.7 2.5 1.1 10.7 5.8 2.4 9.9 11.1 5.9 5.1 8.6 4.3 5.2 5.5 5.7 12.7 4.7 2.9 9.6 2.5 10.7 1.3 2.5 6.2 10.1 4.7 2.4 3.9 10.0 2.3 10.3 3.7 2.0 9.0 16.4 1.9 10.4 5.1 5.3 2.3 3.2 4.6 1.6 3.4 1.8 20.5 2.4 1.3 6.4 11.2 2.0 0.8 2.5 24.8 2.6 19.8 17.0 4.5 9.2 5.8 3.3 2.3 1.1 4.3 0.0 2.2 5.9 4.2 4.7 3.9 2.0 2.2 0.0 4.9 0.2 4.6 1.3 1.4 4.2 1.0 32.3 3.6 7.6 2.4 12.6 0.7 2.8 1.5 3.6 9.7 6.2 0.8 1.1 6.4 1.3 4.2 5.1 15.3 0.4 5.3 11.8 3.4 6.5 7.0 5.6 1.6 5.7 3.0 3.8 3.8 13.9 10.4 15.0 3.8 3.3 2.5 0.4 15.0 3.5 16.5 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.2 2.4 2.5 5.8 2.4 4.7 2.9 2.5 6.2 2.3 2.3 3.4 2.0 5.7 3.2 1.5 4.6 1.1 4.2 44.9 7.0 10.8 1.6 27.7 29.5 18.5 45.8 4.6 12.9 2.1 3.4 0.6 7.4 0.0 4.3 0.3 12.0 13.1 4.5 3.5 0.8 0.6 2.0 2.2 18.5 2.0 15.7 12.7 1.8 15.4 0.9 3.5 141.3 1.0 3.0 4.1 17.4 16.2 1.1 33.2 14.3 17.8 1.9 4.6 3.0 1.0 1.0 0.2 1.9 4.8 45.1 0.4 11.7 6.0 11.6 2.4 2.9 0.0 6.2 10.3 0.5 3.7 9.1 5.1 2.1 0.6 2.6 4.6 7.3 GALNT11 GalNAc-T11 ENSG00000178234 "Polypeptide N-acetylgalactosaminyltransferase 11" Q8NCW6 7 152025674-152122340 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Notch signaling pathway" "Glycosyltransferase, Transferase" Heterotaxy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 408.0;kidney: 229.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 131.1;Inhibitory neurons: 130.7;Proximal tubular cells: 196.7" "Cancer enhanced" "Detected in all" "renal cancer: 30.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039330 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039330: AB_10795249" "unprognostic (6.09e-2)" "unprognostic (1.22e-1)" "unprognostic (4.98e-2)" "unprognostic (3.48e-2)" "prognostic unfavorable (9.54e-4)" "unprognostic (1.76e-1)" "unprognostic (9.10e-3)" "unprognostic (1.56e-3)" "unprognostic (1.38e-1)" "unprognostic (3.65e-1)" "unprognostic (3.82e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.24e-6)" "unprognostic (1.33e-1)" "unprognostic (1.17e-1)" "unprognostic (2.97e-1)" "unprognostic (9.51e-2)" 32.4 25.4 27.9 15.2 30.7 12.7 29.0 24.1 29.3 23.7 408.0 21.9 14.5 23.8 24.6 26.3 22.4 26.1 26.4 39.1 25.1 229.5 19.9 27.5 16.1 20.8 23.9 28.1 84.1 58.0 24.4 45.8 21.6 32.3 17.6 40.6 22.8 25.6 28.4 23.8 15.0 24.2 16.9 20.5 22.0 11.8 30.3 23.8 34.4 26.0 17.8 24.2 24.0 27.0 28.9 25.4 36.8 41.2 83.1 81.3 37.7 22.6 25.6 18.6 17.4 20.7 29.7 0.1 57.8 36.8 51.8 13.3 17.6 31.9 22.8 23.5 26.3 5.8 23.4 18.2 27.3 26.2 29.3 72.1 40.3 15.5 13.0 32.3 34.1 19.9 29.5 0.2 47.0 24.9 22.7 23.6 30.4 45.1 20.2 0.1 16.1 0.9 61.1 43.8 32.6 43.3 37.5 18.0 31.0 39.0 26.8 22.3 31.1 24.8 8.8 31.6 25.1 8.4 11.4 0.5 51.6 25.1 86.6 10.2 12.7 13.5 28.1 15.2 27.8 9.5 15.4 25.8 13.0 5.7 13.1 19.9 6.6 26.2 21.3 4.0 12.7 14.4 27.9 30.7 24.1 29.3 39.1 25.1 20.8 23.9 21.6 16.9 30.3 27.0 28.7 12.8 25.2 44.4 12.9 10.5 24.6 20.5 13.1 123.9 23.5 20.7 30.7 15.7 16.1 35.0 27.1 84.0 49.1 8.7 60.7 17.8 4.8 31.5 38.8 22.8 22.8 7.8 131.1 18.7 13.5 33.8 11.7 57.1 14.5 26.0 22.1 15.8 25.3 75.7 130.7 10.0 8.2 19.7 12.5 3.5 19.9 21.7 17.8 46.9 18.0 37.8 43.3 54.3 42.0 13.0 8.3 36.1 20.3 26.3 9.6 196.7 21.2 39.4 0.0 36.3 25.0 38.7 27.5 24.7 11.8 36.3 29.1 24.3 9.3 19.1 GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174680-16231992 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 157.4;brain: 141.7" "Cell type enhanced" "Detected in many" "Adipocytes: 103.9;Astrocytes: 34.6;Early spermatids: 26.6;Endothelial cells: 26.9;Hepatic stellate cells: 41.7;Muller glia cells: 47.4;Oligodendrocytes: 69.3" "Cancer enriched" "Detected in many" 5 "glioma: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "ASC diff: 133.0;ASC TERT1: 128.8;HSkMC: 102.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 40000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Cytosol "HPA017076: AB_1849458" "unprognostic (3.87e-1)" "unprognostic (4.84e-4)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (7.40e-4)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (8.28e-6)" "unprognostic (5.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-3)" "unprognostic (1.88e-1)" "unprognostic (8.51e-2)" "unprognostic (1.78e-3)" 157.4 4.9 45.1 1.7 55.8 2.7 87.2 62.5 49.3 12.3 14.4 21.7 3.0 11.4 11.9 12.4 24.9 5.6 18.1 47.9 90.8 11.8 4.0 9.4 4.1 137.6 60.4 22.3 3.6 2.4 3.5 32.3 130.8 6.0 3.9 13.4 25.5 4.7 36.3 41.7 21.2 7.0 102.4 12.3 15.3 9.1 62.8 4.0 18.3 35.3 1.3 33.0 22.8 141.7 0.4 1.3 0.9 1.0 133.0 128.8 0.3 3.4 2.5 0.4 1.3 0.0 0.5 0.5 1.9 7.8 2.3 0.8 0.5 1.4 2.0 0.6 1.4 1.1 1.9 0.0 7.4 1.5 0.4 102.8 0.0 1.2 1.8 2.4 2.8 0.7 0.2 3.0 1.1 1.9 0.0 2.1 0.5 0.8 1.1 0.3 1.1 24.1 0.5 0.5 0.4 0.3 0.4 1.0 0.6 0.6 0.7 1.8 3.9 0.6 4.3 26.8 0.6 1.4 5.1 1.4 2.5 0.4 0.4 0.5 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 45.1 55.8 62.5 49.3 47.9 90.8 137.6 60.4 130.8 102.4 62.8 141.7 103.9 0.0 1.7 34.6 0.1 0.5 0.4 0.0 0.0 3.8 1.1 0.9 2.8 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 26.6 0.5 3.3 26.9 0.0 0.0 4.9 0.0 0.1 24.7 0.0 1.0 1.3 0.1 41.7 1.8 0.1 0.0 3.9 0.0 0.0 0.8 2.1 16.7 1.8 0.5 0.0 22.5 0.1 47.4 0.0 5.0 69.3 0.2 0.0 0.7 1.8 2.1 0.0 0.1 0.0 3.2 0.0 7.3 2.1 25.5 0.5 0.1 0.9 0.0 0.2 0.3 0.0 0.3 GALNT16 "GalNAc-T16, GALNTL1, KIAA1130" ENSG00000100626 "Polypeptide N-acetylgalactosaminyltransferase 16" Q8N428 14 69259277-69357033 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.8;heart muscle: 45.0" "Cell type enhanced" "Detected in many" "Astrocytes: 16.6;Cardiomyocytes: 46.7;Excitatory neurons: 27.6;Fibroblasts: 24.0;Inhibitory neurons: 23.8;Smooth muscle cells: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.5;ASC diff: 11.7;hTEC/SVTERT24-B: 17.0;hTERT-RPE1: 17.2;SCLC-21H: 8.7;U-2 OS: 19.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059136, HPA075325" Approved Approved Vesicles,Cytosol NA NA 370000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA059136: AB_2683919, HPA075325: " "unprognostic (9.71e-3)" "unprognostic (7.47e-2)" "unprognostic (4.02e-1)" "unprognostic (2.30e-2)" "unprognostic (6.71e-2)" "unprognostic (5.72e-3)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-4)" "unprognostic (1.31e-2)" "prognostic favorable (5.23e-6)" "unprognostic (5.38e-3)" "unprognostic (3.34e-2)" "unprognostic (3.93e-2)" "unprognostic (7.96e-5)" 14.4 11.6 25.7 2.0 24.4 0.1 12.0 14.7 28.4 7.6 6.5 6.5 2.2 7.3 2.8 3.6 5.6 3.4 45.0 27.0 35.5 7.7 2.0 3.4 3.2 19.6 22.5 2.1 4.3 2.5 4.7 0.4 19.9 4.0 2.2 1.3 23.5 4.6 4.4 7.5 3.7 8.6 16.4 12.1 3.2 3.5 40.8 2.2 4.9 5.8 1.3 3.1 5.0 21.3 0.0 0.8 8.5 0.3 11.7 5.3 0.0 1.3 0.1 1.5 2.3 0.4 0.0 0.0 0.2 1.4 0.8 0.0 3.0 0.0 0.3 0.1 6.0 0.0 0.2 0.5 0.1 0.0 0.5 0.5 0.0 17.0 0.0 17.2 0.9 0.0 0.0 0.0 2.8 0.5 0.0 0.0 1.7 0.0 0.1 0.0 4.8 0.0 0.5 0.0 8.7 3.0 1.8 0.4 0.0 0.3 0.3 0.0 0.1 1.7 19.9 2.2 2.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 24.4 14.7 28.4 27.0 35.5 19.6 22.5 19.9 16.4 40.8 21.3 4.0 0.0 0.0 16.6 0.0 4.1 0.4 0.0 0.0 2.8 3.1 3.0 46.7 0.0 0.0 0.0 2.1 0.1 0.2 0.0 3.9 0.1 9.7 0.2 0.4 1.7 0.0 0.0 27.6 0.0 0.0 24.0 0.5 0.2 0.0 0.3 0.0 0.0 0.2 0.0 23.8 0.1 0.0 0.0 6.1 11.2 0.9 0.3 3.6 5.6 0.0 0.1 0.0 8.0 1.6 0.0 0.0 3.8 0.0 0.5 0.1 0.1 0.0 0.8 6.6 10.1 14.8 0.6 2.1 0.3 3.3 0.0 0.3 11.2 0.6 0.4 GBE1 ENSG00000114480 "1,4-alpha-glucan branching enzyme 1" Q04446 3 81489703-81761645 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 149.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 287.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038073, HPA038074, HPA038075" Enhanced Approved Cytosol NA NA 6500000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA038073: AB_10673040, HPA038074: AB_10672403, HPA038075: AB_10674545" "unprognostic (3.10e-1)" "unprognostic (1.02e-3)" "unprognostic (6.76e-2)" "unprognostic (1.05e-2)" "unprognostic (3.48e-2)" "unprognostic (1.89e-1)" "unprognostic (9.01e-3)" "unprognostic (1.17e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (2.19e-2)" "unprognostic (5.68e-2)" "unprognostic (1.46e-1)" "unprognostic (5.36e-2)" "unprognostic (4.42e-1)" "unprognostic (2.83e-3)" "unprognostic (3.78e-3)" 73.9 53.8 4.5 14.9 5.7 19.7 38.6 7.1 8.2 14.2 14.2 11.8 13.2 17.3 14.2 18.1 13.8 13.0 55.6 6.2 8.2 41.4 108.6 17.2 8.6 10.7 18.7 14.2 14.2 19.1 10.4 25.6 10.3 13.2 13.8 22.0 15.5 14.9 149.1 14.4 11.5 21.8 7.0 12.0 11.1 7.9 7.4 11.4 19.6 56.6 13.2 19.2 13.9 7.4 61.3 36.2 11.9 168.7 287.6 216.8 21.5 99.1 140.1 58.1 97.6 7.1 15.6 67.9 42.7 122.5 34.5 7.1 9.9 45.7 135.4 32.3 6.4 21.2 70.0 22.8 197.5 72.2 17.8 161.2 33.2 93.5 95.5 144.9 130.5 8.0 17.0 38.0 191.1 17.8 12.5 92.7 12.0 16.8 58.0 22.9 53.6 81.1 41.4 20.5 6.0 7.9 64.6 18.7 20.9 17.2 13.3 58.9 183.4 118.9 28.1 84.7 92.8 174.8 21.4 24.6 194.1 47.8 49.8 7.5 11.8 15.6 5.2 10.8 5.1 11.6 5.6 5.7 13.8 12.5 6.4 6.6 11.4 13.5 11.8 4.8 5.1 6.5 4.5 5.7 7.1 8.2 6.2 8.2 10.7 18.7 10.3 7.0 7.4 7.4 49.7 16.0 12.4 31.3 14.9 30.7 22.2 36.8 27.3 18.6 7.5 5.5 60.2 15.7 21.9 31.3 0.0 30.3 8.4 9.5 41.1 32.1 36.2 16.3 15.2 32.0 22.1 4.6 52.4 25.4 74.0 34.9 6.6 14.7 43.1 16.0 15.4 75.2 26.3 30.3 47.4 8.7 12.2 12.9 21.3 16.9 17.4 17.3 24.9 87.1 16.3 10.4 7.2 49.3 63.0 37.8 5.8 13.2 12.8 17.7 11.3 50.8 25.0 17.8 32.9 45.8 26.7 6.9 7.3 20.6 21.3 54.9 8.7 34.2 8.3 14.5 GCC2 "GCC185, KIAA0336" ENSG00000135968 "GRIP and coiled-coil domain containing 2" Q8IWJ2 2 108449191-108509415 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035849, HPA035850" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" Nucleoplasm "HPA035849: AB_10671941, HPA035850: AB_2674821" "unprognostic (1.35e-1)" "unprognostic (1.29e-2)" "unprognostic (2.45e-2)" "unprognostic (2.04e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (1.59e-1)" "unprognostic (3.11e-2)" "unprognostic (2.02e-1)" "unprognostic (1.06e-1)" "unprognostic (6.53e-2)" "unprognostic (6.53e-3)" "unprognostic (3.99e-1)" "unprognostic (4.71e-1)" "unprognostic (9.61e-2)" "unprognostic (1.64e-2)" 9.0 12.7 3.4 17.6 5.1 25.2 17.4 0.0 5.5 12.5 26.2 19.2 21.7 15.3 41.7 7.5 15.0 21.4 8.4 3.2 3.8 16.6 10.7 14.8 21.5 2.5 4.2 15.5 12.5 15.0 4.1 13.7 2.8 19.6 20.8 17.3 15.2 17.1 2.3 7.9 22.9 9.4 0.9 18.8 26.4 16.6 1.4 18.9 20.5 9.4 16.3 14.1 3.6 6.0 12.5 10.4 12.6 5.5 14.2 22.6 27.4 17.6 26.8 9.2 12.9 18.4 17.2 14.9 22.3 16.0 16.7 10.4 10.0 14.1 15.8 16.9 13.6 18.7 16.3 15.8 12.7 26.4 14.3 29.1 13.3 23.1 16.3 20.0 13.6 13.9 25.3 12.4 17.4 7.1 13.6 18.1 21.9 11.5 12.0 11.7 17.9 16.1 12.2 20.1 13.6 12.5 21.1 16.7 18.7 18.2 8.3 12.8 21.3 13.3 20.2 12.4 6.7 18.0 26.9 18.2 17.2 7.0 9.8 47.3 8.9 25.9 25.5 8.0 25.1 27.0 28.2 27.8 7.3 24.3 38.2 33.5 35.6 14.9 17.6 31.8 23.0 8.2 3.4 5.1 0.0 5.5 3.2 3.8 2.5 4.2 2.8 0.9 1.4 6.0 92.6 150.6 103.3 44.1 125.2 23.8 68.6 54.8 29.6 155.9 60.3 57.5 85.6 75.8 95.7 104.8 139.7 44.2 157.6 152.1 50.9 114.5 73.9 253.3 85.1 68.1 85.6 39.5 104.9 81.6 56.3 74.2 65.7 118.6 82.2 113.9 65.0 36.7 37.0 70.7 73.6 152.6 52.9 49.8 39.3 39.9 71.4 66.0 33.8 62.8 88.5 59.0 134.9 50.8 66.1 116.1 125.2 82.8 108.7 91.7 134.0 63.1 259.7 127.2 52.6 61.4 66.2 163.0 120.7 21.0 17.5 65.0 139.1 138.0 88.3 114.5 GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501693-19522123 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 270.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077420 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "Nucleoplasm, Plasma membrane" "HPA077420: " "unprognostic (1.69e-1)" "unprognostic (5.13e-2)" "prognostic favorable (3.12e-4)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (7.52e-5)" "unprognostic (2.10e-2)" "unprognostic (1.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.60e-3)" "unprognostic (9.92e-2)" "prognostic favorable (3.12e-5)" "unprognostic (8.36e-2)" "unprognostic (9.69e-3)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" 28.9 25.9 42.9 15.6 46.3 27.8 21.1 42.9 49.9 21.9 40.4 44.9 30.0 20.0 27.5 22.4 16.9 18.4 52.8 45.7 45.5 27.6 25.4 29.3 11.7 44.5 47.7 12.8 28.5 76.8 19.2 20.5 43.3 26.7 41.6 19.8 28.3 30.3 62.9 26.4 27.7 26.5 42.8 13.5 34.3 14.1 48.8 16.8 20.3 64.4 15.3 30.2 16.6 47.4 38.6 46.2 25.0 29.4 115.3 43.3 34.7 38.3 66.9 30.0 37.1 26.6 67.4 29.2 48.1 57.2 32.8 31.8 35.2 46.6 36.9 31.7 52.8 24.2 41.4 57.2 69.1 32.7 21.5 44.9 73.1 32.2 37.4 54.5 40.6 36.3 13.7 29.1 33.2 70.3 28.3 29.1 29.1 59.9 34.2 40.2 45.7 41.7 72.9 59.7 28.9 25.8 37.0 44.5 37.9 38.5 45.8 37.8 42.7 25.3 22.3 33.9 24.6 27.0 27.4 19.9 38.5 47.2 23.1 52.0 19.3 11.2 8.9 17.7 11.5 7.2 10.4 10.4 12.4 6.1 5.5 8.5 34.0 6.6 22.7 7.5 12.7 8.2 42.9 46.3 42.9 49.9 45.7 45.5 44.5 47.7 43.3 42.8 48.8 47.4 12.2 38.5 86.8 7.2 18.9 23.5 30.3 56.2 22.8 15.4 38.3 22.4 66.8 34.3 56.0 9.2 27.1 80.4 23.2 123.1 23.5 97.0 35.1 26.9 23.8 17.7 33.5 100.8 12.0 163.9 78.6 27.3 24.5 21.5 3.8 36.4 20.7 23.9 60.8 32.0 15.9 57.5 61.1 48.2 22.9 61.2 28.6 32.3 24.9 8.4 38.2 22.3 24.7 9.5 25.0 77.4 97.6 38.0 19.6 100.5 101.7 45.9 39.7 29.6 13.1 16.7 24.9 87.1 59.6 31.9 29.5 270.4 22.0 45.9 85.3 79.2 GDF5 "BMP14, CDMP1" ENSG00000125965 "Growth differentiation factor 5" P43026 20 35433347-35454746 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Chondrogenesis "Cytokine, Growth factor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "salivary gland: 9.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.2;Basal prostatic cells: 1.0;granulocytes: 1.3" "Cancer enriched" "Detected in single" 7 "endometrial cancer: 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 17.6;BJ hTERT+: 5.4;GAMG: 9.4;HHSteC: 5.8;HSkMC: 14.4;U-87 MG: 6.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA015648 Uncertain "Secreted to blood" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "HPA015648: AB_1849589" "unprognostic (4.59e-3)" "unprognostic (3.48e-2)" "unprognostic (5.53e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (4.64e-1)" "unprognostic (2.17e-3)" "unprognostic (4.38e-2)" "unprognostic (1.40e-1)" "unprognostic (8.02e-2)" "unprognostic (2.77e-1)" "unprognostic (5.57e-3)" "unprognostic (2.13e-2)" "unprognostic (1.24e-1)" "unprognostic (1.38e-1)" "unprognostic (8.96e-3)" 0.9 0.1 0.1 0.0 0.4 0.0 0.6 0.1 0.3 0.3 0.3 1.6 0.0 0.4 0.1 0.0 0.1 0.2 0.4 0.1 0.2 0.3 0.0 2.3 0.0 0.2 0.1 0.0 0.0 0.0 1.7 0.0 0.2 0.9 0.1 0.0 9.9 1.2 0.1 0.1 0.1 0.6 0.1 0.0 0.1 0.6 0.4 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 1.3 17.6 0.1 2.8 5.4 0.4 1.0 0.0 0.0 0.0 0.0 4.5 9.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 5.8 0.0 0.0 14.4 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 3.2 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.4 0.2 0.1 0.0 2.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 GET1 "CHD5, WRB" ENSG00000182093 "Guided entry of tail-anchored proteins factor 1" O00258 21 39377698-39428528 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 12.0;Cardiomyocytes: 38.3;Cytotrophoblasts: 37.6;Extravillous trophoblasts: 35.3;Fibroblasts: 10.4;Hofbauer cells: 31.5;Syncytiotrophoblasts: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018527 Approved NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA018527: AB_1858860" "unprognostic (4.34e-3)" "unprognostic (3.28e-1)" "unprognostic (2.88e-2)" "unprognostic (4.37e-2)" "unprognostic (2.56e-1)" "unprognostic (5.08e-2)" "unprognostic (6.86e-2)" "unprognostic (1.57e-3)" "unprognostic (8.74e-2)" "unprognostic (1.15e-2)" "unprognostic (4.02e-3)" "unprognostic (9.48e-2)" "unprognostic (6.50e-3)" "unprognostic (2.21e-2)" "unprognostic (2.67e-2)" "unprognostic (5.78e-3)" "unprognostic (8.13e-2)" 20.4 44.4 63.7 11.8 66.5 8.9 25.6 65.3 92.7 28.1 85.3 20.4 18.5 29.4 45.8 15.3 71.1 18.8 29.4 65.6 77.8 38.6 33.4 18.9 14.4 65.3 69.1 41.8 17.9 15.6 29.1 22.1 69.8 24.7 14.9 111.3 16.1 21.1 38.1 10.1 18.7 23.2 67.9 13.7 17.4 55.9 73.3 15.9 28.5 30.1 14.8 16.1 15.1 74.2 36.8 33.2 58.9 34.6 74.8 69.7 18.6 50.6 51.2 23.8 21.7 31.2 50.3 59.6 35.0 54.9 29.0 13.8 47.5 31.8 33.5 26.4 32.2 43.0 28.5 50.8 44.7 33.3 15.8 44.8 30.3 37.9 34.7 67.0 60.2 61.2 65.8 36.8 63.4 82.4 38.4 25.3 52.8 66.7 25.0 42.1 34.6 44.4 69.1 19.1 29.2 44.5 44.7 23.1 53.9 31.1 43.1 37.7 35.6 30.2 10.6 41.2 23.0 46.4 70.4 27.3 72.3 55.3 34.2 37.7 26.7 27.6 19.8 20.4 17.6 30.8 24.1 20.8 30.7 20.6 27.0 25.6 47.1 27.3 21.2 39.4 23.8 39.5 63.7 66.5 65.3 92.7 65.6 77.8 65.3 69.1 69.8 67.9 73.3 74.2 12.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.0 37.6 2.9 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 35.3 10.4 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 13.7 0.6 0.0 0.0 0.0 GGCX VKCFD1 ENSG00000115486 "Gamma-glutamyl carboxylase" P38435 2 85544720-85561547 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 118.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018284 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA018284: AB_1849641" "unprognostic (4.88e-3)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (1.82e-6)" "unprognostic (5.67e-2)" "unprognostic (1.85e-3)" "unprognostic (2.96e-2)" "unprognostic (3.77e-2)" "unprognostic (5.64e-2)" "unprognostic (2.18e-2)" "unprognostic (6.45e-3)" "unprognostic (5.23e-2)" "unprognostic (8.17e-3)" "unprognostic (7.85e-2)" "unprognostic (2.59e-1)" "unprognostic (7.63e-3)" "unprognostic (9.38e-2)" 13.8 11.0 6.0 8.3 7.4 3.2 10.8 8.3 7.7 10.7 11.7 7.8 7.4 10.5 13.8 9.2 10.5 11.3 9.5 6.9 6.2 16.3 118.8 13.8 6.3 7.4 6.9 12.4 15.8 18.0 7.8 23.4 7.5 10.0 9.9 7.7 14.7 12.1 7.9 9.2 7.3 13.4 7.3 6.2 9.1 4.7 7.0 4.8 12.6 8.6 7.2 12.2 8.8 11.2 17.1 27.2 19.0 21.3 93.8 26.6 42.2 29.9 35.1 21.6 30.4 47.3 20.6 6.1 29.7 49.3 27.1 27.2 13.7 37.7 23.7 10.9 18.7 11.1 17.4 45.2 34.8 7.0 10.1 33.1 22.0 43.8 29.7 35.6 31.0 10.8 13.5 8.7 63.5 22.4 3.5 5.3 8.9 47.7 23.4 6.6 44.6 15.3 30.0 32.5 7.2 12.1 26.8 52.2 28.2 32.1 25.6 6.8 28.6 27.5 23.9 27.1 20.9 6.8 20.1 5.1 26.5 7.1 39.4 3.7 4.2 2.2 1.7 4.4 1.6 0.4 0.7 0.7 2.9 0.4 1.7 1.6 1.7 1.4 2.6 2.4 1.2 2.0 6.0 7.4 8.3 7.7 6.9 6.2 7.4 6.9 7.5 7.3 7.0 11.2 27.1 28.9 40.3 10.1 25.1 18.7 20.6 27.8 13.6 21.6 22.9 19.8 27.9 32.9 24.1 29.5 16.7 60.8 28.4 16.1 7.9 29.9 4.2 16.9 19.4 20.8 14.4 5.7 10.9 39.5 50.2 29.4 11.7 26.8 15.8 17.8 23.9 163.0 31.3 8.4 8.9 17.6 22.4 26.9 29.0 2.2 20.2 24.5 21.4 5.6 29.6 19.5 17.5 9.5 12.6 25.0 12.6 20.3 38.4 16.4 16.2 27.1 16.9 33.6 6.6 42.3 22.8 23.5 11.2 20.0 15.2 53.8 20.8 15.1 16.4 23.6 GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 42.8;Fibroblasts: 58.3;Leydig cells: 36.4;Sertoli cells: 184.1;Smooth muscle cells: 85.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3;eosinophil: 4.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 164.9;ASC TERT1: 124.4;HHSteC: 234.7;HSkMC: 271.7;TIME: 110.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" NA NA 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (6.36e-5)" "prognostic unfavorable (4.06e-4)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" 137.6 60.5 39.0 18.6 39.3 1.4 90.6 37.6 41.7 73.2 32.8 27.8 19.4 54.4 12.9 19.6 70.6 37.2 93.4 35.0 45.1 78.2 55.2 37.7 48.0 52.2 46.3 26.6 25.8 13.2 41.1 11.9 46.9 49.3 12.0 2.1 37.1 20.9 23.1 40.1 40.8 32.2 41.9 36.1 40.0 9.6 45.3 10.4 110.2 16.6 18.3 45.1 64.2 38.2 0.0 1.8 0.6 0.0 164.9 124.4 1.1 2.9 0.2 0.1 0.0 0.1 0.1 0.2 3.4 0.2 0.3 0.3 0.1 0.1 0.0 2.2 0.9 6.7 1.0 24.1 234.7 3.0 6.4 271.7 0.1 3.4 3.2 0.4 45.8 0.7 0.4 1.2 44.1 0.4 0.0 22.4 3.6 1.1 0.0 0.1 4.0 1.0 6.1 0.0 0.4 5.9 0.1 7.3 0.1 22.7 1.0 1.7 110.8 0.1 2.3 0.1 0.0 0.3 1.5 0.2 3.9 5.7 0.2 2.3 0.5 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.2 39.0 39.3 37.6 41.7 35.0 45.1 52.2 46.3 46.9 41.9 45.3 38.2 27.2 3.2 16.0 1.0 0.3 7.0 3.3 3.2 0.0 0.0 7.2 4.2 4.4 0.0 17.9 0.0 0.0 0.2 0.4 0.0 0.0 0.6 0.8 0.3 8.3 42.8 0.0 2.7 0.1 0.2 0.2 58.3 1.1 0.4 1.3 0.0 33.5 0.1 2.1 0.0 0.1 0.0 0.0 1.0 12.5 3.3 36.4 1.8 3.6 22.5 3.3 0.3 0.0 0.5 0.0 0.4 0.0 23.7 0.3 2.2 0.0 0.1 2.2 1.0 184.1 33.9 85.6 0.6 0.4 0.3 4.4 0.3 1.1 2.1 0.0 1.4 GINM1 "C6orf72, dJ12G14.2" ENSG00000055211 "Glycoprotein integral membrane 1" Q9NU53 6 149566294-149591748 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 369.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017210, HPA041679" Approved Approved "Nucleoli fibrillar center,Plasma membrane" NA NA 35000 "Cluster 19: B-cells - Humoral immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center, Plasma membrane" "HPA017210: AB_1845743, HPA041679: AB_2677611" "unprognostic (6.09e-3)" "unprognostic (2.19e-2)" "unprognostic (2.38e-1)" "unprognostic (2.48e-1)" "unprognostic (7.24e-2)" "unprognostic (1.32e-3)" "unprognostic (3.18e-2)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" "unprognostic (8.23e-2)" "unprognostic (1.05e-1)" "unprognostic (2.10e-2)" "unprognostic (2.09e-2)" "unprognostic (2.88e-2)" "unprognostic (2.64e-2)" "unprognostic (4.87e-2)" "unprognostic (4.79e-3)" 56.0 44.0 25.7 24.0 31.4 41.2 45.0 33.9 36.1 47.8 38.5 43.0 25.9 46.4 44.6 32.2 39.2 38.2 58.6 25.0 28.9 92.7 45.7 36.0 26.1 30.6 29.0 50.5 36.8 55.3 24.7 62.6 30.6 40.3 34.8 21.9 32.2 47.4 47.1 36.4 28.1 50.5 29.3 35.1 34.1 48.0 26.9 21.7 73.9 42.3 24.7 42.2 34.0 38.9 27.2 19.5 30.5 41.4 162.6 96.1 48.3 89.0 107.5 68.1 85.1 25.4 35.7 19.4 46.9 87.6 62.9 53.8 20.1 46.0 89.0 33.6 39.6 18.9 17.5 30.5 62.0 37.2 17.2 107.8 39.1 58.0 39.6 74.7 74.7 27.0 24.6 31.8 65.1 35.3 22.9 27.9 10.1 40.2 20.1 25.2 54.0 15.1 97.7 23.9 19.2 18.1 90.1 53.2 18.9 33.5 32.9 38.4 51.3 35.9 37.0 92.9 60.9 30.6 38.6 24.5 67.4 33.1 34.3 21.0 18.5 25.1 8.8 17.8 10.5 22.8 10.2 9.7 13.9 17.0 9.8 8.0 32.1 11.4 23.4 16.9 10.7 10.6 25.7 31.4 33.9 36.1 25.0 28.9 30.6 29.0 30.6 29.3 26.9 38.9 120.5 80.1 53.7 10.1 44.6 46.8 58.6 75.1 46.7 21.3 50.1 50.3 54.1 38.6 53.4 66.2 29.2 81.1 31.4 64.5 39.2 92.7 191.0 42.2 77.3 78.9 26.8 32.2 11.9 80.7 77.1 103.4 18.3 60.7 29.1 48.2 104.6 41.9 45.6 16.8 13.9 23.1 46.8 56.0 47.7 369.6 129.5 46.6 42.7 5.6 75.7 86.5 18.6 17.1 25.0 67.8 33.5 112.8 45.3 65.0 49.8 132.1 33.8 22.6 98.6 85.9 71.1 166.5 82.8 48.7 47.0 122.7 32.0 65.7 22.4 64.0 GLMP "C1orf85, MGC31963, NCU-G1" ENSG00000198715 "Glycosylated lysosomal membrane protein" Q8WWB7 1 156290089-156295689 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029121 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA029121: AB_10600794" "unprognostic (2.46e-2)" "unprognostic (1.19e-2)" "unprognostic (5.68e-2)" "unprognostic (4.22e-3)" "unprognostic (3.71e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.35e-5)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (9.21e-3)" "unprognostic (1.33e-1)" "unprognostic (7.66e-3)" "unprognostic (7.68e-3)" "unprognostic (3.90e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" 33.9 68.3 11.8 17.1 12.8 19.4 25.6 12.9 15.4 38.1 21.1 24.6 30.3 24.4 23.2 29.8 21.1 44.7 18.1 11.7 13.9 52.2 59.8 28.9 22.6 13.6 13.6 22.0 27.0 29.4 19.7 48.0 15.0 57.3 21.1 2.7 35.2 20.4 7.4 29.2 26.9 24.5 12.4 32.3 28.8 6.4 16.0 12.2 23.6 9.6 15.4 36.0 26.8 14.4 22.7 40.8 3.9 27.0 224.8 121.7 27.5 40.8 172.0 58.1 79.0 50.9 68.7 0.0 83.2 59.0 1.9 14.6 0.6 30.0 18.4 4.6 41.8 7.0 22.9 60.6 101.4 19.7 58.1 119.9 36.0 55.9 17.9 85.1 89.0 17.6 32.8 3.1 34.6 28.5 10.1 0.1 46.5 56.9 20.9 17.4 0.0 74.3 53.7 24.5 12.9 42.2 27.1 76.4 120.6 45.6 38.3 54.2 45.7 25.7 5.0 46.2 26.9 24.9 45.9 11.3 44.0 15.7 36.3 35.0 71.3 12.2 23.4 74.5 21.7 13.1 23.0 20.5 31.8 7.7 22.7 21.7 19.4 18.0 55.6 21.3 43.4 36.9 11.8 12.8 12.9 15.4 11.7 13.9 13.6 13.6 15.0 12.4 16.0 14.4 11.7 3.2 19.1 3.3 7.3 0.0 16.4 0.0 10.8 2.0 12.3 11.6 5.8 31.5 5.0 31.3 0.0 70.3 7.6 13.8 27.4 51.3 0.6 8.5 19.1 17.5 10.9 18.5 1.6 38.3 68.5 33.4 18.8 14.2 8.8 14.9 42.8 69.8 197.7 1.7 1.9 19.4 0.0 66.8 0.0 1.4 16.4 41.1 0.0 1.0 29.8 21.0 13.4 2.0 3.9 29.8 22.2 13.9 23.0 28.9 44.9 67.3 5.8 1.5 13.1 11.9 17.1 0.9 1.9 17.8 0.0 69.6 9.3 17.6 11.8 18.7 GLT8D1 "AD-017, FLJ14611" ENSG00000016864 "Glycosyltransferase 8 domain containing 1" Q68CQ7 3 52694486-52706032 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 149.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010588 Approved Approved Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA010588: AB_1078098" "unprognostic (1.37e-1)" "unprognostic (2.96e-1)" "unprognostic (1.38e-2)" "prognostic favorable (2.76e-4)" "unprognostic (3.17e-2)" "unprognostic (1.55e-1)" "unprognostic (2.03e-1)" "unprognostic (1.82e-3)" "unprognostic (7.12e-2)" "unprognostic (9.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.07e-1)" "unprognostic (5.82e-3)" "unprognostic (2.42e-3)" "unprognostic (3.97e-1)" "unprognostic (3.34e-2)" "unprognostic (6.21e-2)" 33.1 39.8 25.4 22.5 26.6 9.3 35.6 25.2 29.3 47.5 35.6 27.7 25.9 35.0 41.3 18.3 54.4 29.8 32.6 26.2 26.7 40.4 69.5 29.6 25.3 24.0 26.9 53.8 35.7 46.0 64.8 48.2 25.5 30.5 32.3 32.2 29.9 32.7 20.8 22.6 23.4 32.2 25.9 24.6 28.9 64.5 26.4 29.2 64.0 24.6 26.8 31.6 28.6 28.6 28.7 33.2 65.7 52.0 142.6 179.8 36.8 70.3 107.8 60.6 69.1 15.5 52.6 24.0 19.7 122.7 73.3 31.9 42.1 72.0 79.5 43.5 30.6 22.8 61.4 71.7 68.3 34.0 68.5 104.1 62.9 52.1 66.8 139.8 91.3 40.6 29.4 53.6 80.6 29.2 23.4 51.8 33.8 49.8 61.5 17.4 37.3 81.9 71.3 30.8 26.9 46.5 58.6 27.9 48.9 61.2 47.7 44.2 67.1 43.7 33.9 63.9 39.6 60.2 73.7 26.4 76.0 53.2 56.2 38.4 13.0 21.8 19.1 8.5 18.3 14.1 22.2 20.0 11.8 9.8 22.3 15.6 6.9 30.3 9.3 23.1 16.8 10.9 25.4 26.6 25.2 29.3 26.2 26.7 24.0 26.9 25.5 25.9 26.4 28.6 25.8 0.0 9.6 16.0 16.0 12.1 16.1 40.3 13.6 41.5 18.1 19.7 15.3 17.2 23.8 18.4 12.5 58.4 26.5 9.4 23.5 34.4 71.4 38.5 38.4 22.7 18.6 8.6 17.9 27.1 63.5 59.2 14.8 15.2 5.7 35.6 34.2 38.2 26.9 21.9 16.8 21.1 30.5 13.6 12.0 23.0 53.7 12.3 24.9 8.4 26.5 37.0 34.0 15.6 14.6 23.3 16.9 48.5 39.1 14.7 22.8 21.5 44.4 21.3 26.3 31.6 25.2 149.5 50.0 10.3 8.0 26.1 21.4 74.2 17.3 10.0 GLT8D2 FLJ31494 ENSG00000120820 "Glycosyltransferase 8 domain containing 2" Q9H1C3 12 103988987-104064183 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 26.3;Early spermatids: 41.2;Fibroblasts: 55.9;Leydig cells: 55.9;Peritubular cells: 51.9;Skeletal myocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 69.3;BJ hTERT+: 89.4;HSkMC: 63.2;hTERT-RPE1: 51.9;RPTEC TERT1: 45.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012740, HPA026904, HPA070791" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA012740: , HPA026904: AB_1849731, HPA070791: " "unprognostic (4.02e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (9.53e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (1.71e-1)" "unprognostic (4.34e-3)" "unprognostic (2.57e-1)" "unprognostic (1.25e-1)" "unprognostic (7.55e-2)" "unprognostic (5.03e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (1.58e-6)" "prognostic unfavorable (7.92e-4)" "unprognostic (7.15e-2)" "unprognostic (7.70e-3)" "unprognostic (7.03e-3)" 16.9 10.9 4.2 5.2 4.9 1.5 19.5 2.6 5.1 29.6 11.2 17.6 5.8 27.4 21.6 7.5 22.3 35.8 15.4 4.8 3.7 4.3 2.7 10.2 6.0 2.9 3.1 41.6 4.5 6.6 9.6 9.4 3.1 13.3 11.4 1.0 7.7 16.0 3.2 4.1 7.7 21.8 2.8 1.6 8.4 6.8 3.7 2.2 26.3 11.5 5.8 20.8 18.9 4.4 0.3 0.6 0.7 22.2 28.3 69.3 0.5 32.0 89.4 8.3 10.5 0.4 0.2 0.9 1.8 37.5 0.4 0.1 0.4 11.9 7.0 1.6 10.0 0.6 11.2 0.2 12.7 0.9 0.5 63.2 0.7 10.0 13.8 51.9 4.4 0.6 0.4 1.3 36.5 0.3 0.8 0.5 2.7 0.1 6.7 1.0 33.6 0.2 45.5 0.4 1.3 1.7 33.5 0.8 0.4 2.4 6.0 0.5 0.7 13.2 6.2 1.3 1.9 3.9 0.8 0.3 1.0 0.7 1.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.2 4.9 2.6 5.1 4.8 3.7 2.9 3.1 3.1 2.8 3.7 4.4 8.0 0.0 4.6 2.9 0.3 2.8 4.2 2.4 0.0 0.8 1.0 26.3 3.9 1.5 0.1 0.0 2.1 4.1 0.4 0.0 0.0 0.1 41.2 0.6 8.3 7.5 1.8 0.0 10.2 0.0 0.8 55.9 1.1 0.4 0.0 0.1 20.7 0.3 0.6 0.0 10.5 1.3 0.0 0.6 2.8 11.5 55.9 0.4 3.6 4.7 0.6 0.5 0.0 1.0 2.6 0.3 0.0 51.9 1.2 1.4 0.0 0.0 0.1 0.5 6.6 25.2 18.0 1.1 1.1 0.2 2.4 1.4 0.6 10.7 0.0 0.1 GLUL GLNS ENSG00000135821 "Glutamate-ammonia ligase" P15104 1 182378098-182392206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Ligase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1443.6" "Group enriched" "Detected in all" 4 "Late spermatids: 8544.2;Muller glia cells: 6247.0" "Cancer enhanced" "Detected in all" "liver cancer: 365.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 656.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 656.8" "Cell line enhanced" "Detected in many" "ASC diff: 1150.8;ASC TERT1: 807.6;HSkMC: 702.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007316, HPA007571, CAB008636" Approved Supported "Plasma membrane,Mitochondria,Cytosol" NA NA 150000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" "Plasma membrane" "CAB008636: AB_1616669, HPA007316: AB_888438, HPA007571: AB_1078980" "prognostic favorable (4.81e-4)" "unprognostic (1.52e-3)" "unprognostic (3.89e-1)" "unprognostic (3.32e-1)" "unprognostic (1.25e-1)" "unprognostic (9.52e-2)" "unprognostic (7.58e-2)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-2)" "unprognostic (4.17e-2)" "unprognostic (2.06e-1)" "unprognostic (5.55e-2)" "unprognostic (4.53e-3)" 753.5 76.0 694.3 156.9 746.5 232.9 573.5 717.5 1237.1 161.4 583.2 157.8 24.4 116.7 115.7 218.7 224.3 105.4 129.7 676.6 764.7 65.3 280.7 221.7 75.2 891.0 783.7 303.0 204.7 32.3 70.5 176.6 767.0 103.4 92.5 891.1 233.5 96.0 1443.6 231.4 148.2 124.1 725.0 216.4 648.2 87.1 811.4 97.0 257.4 472.0 103.2 185.5 292.0 810.4 26.4 10.8 117.2 0.2 1150.8 807.6 86.0 44.1 141.7 25.9 23.4 64.1 26.7 22.4 46.3 85.5 23.8 59.3 51.8 309.4 21.5 61.2 143.3 296.5 47.6 124.8 61.1 132.6 227.2 702.1 363.3 32.9 384.6 39.1 52.8 71.7 254.3 13.3 92.6 15.0 208.2 126.5 87.3 36.8 55.0 74.3 31.3 38.6 45.8 114.0 79.7 52.5 12.4 157.3 17.4 93.3 153.1 165.9 39.7 0.9 1.9 0.8 10.1 4.8 3.4 0.4 22.3 73.9 5.0 396.5 153.4 409.4 42.3 145.8 17.6 11.5 29.9 35.5 80.0 17.8 15.3 25.3 656.8 27.2 130.5 43.7 13.0 172.0 694.3 746.5 717.5 1237.1 676.6 764.7 891.0 783.7 767.0 725.0 811.4 810.4 127.8 125.0 173.8 599.4 37.6 134.7 533.8 1190.7 260.0 105.6 166.6 99.1 216.2 171.6 855.3 82.8 52.1 161.7 113.4 118.3 74.3 124.2 1491.3 140.2 150.0 191.5 325.9 319.7 3.4 116.6 65.9 404.4 388.4 124.6 786.3 88.0 152.8 597.1 798.0 43.7 22.0 256.7 451.6 907.2 614.1 8544.2 487.4 687.4 136.9 74.9 112.7 6247.0 42.2 38.2 330.0 108.1 105.3 375.0 38.7 421.0 10.3 46.6 569.9 176.0 92.1 481.5 218.5 48.2 63.6 186.5 128.3 235.3 108.6 53.3 173.3 1420.5 GNPTG "C16orf27, c316G12.3, CAB56184, GNPTAG" ENSG00000090581 "N-acetylglucosamine-1-phosphate transferase subunit gamma" Q9UJJ9 16 1351931-1364113 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 135.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004055 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 560000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" Cytosol "HPA004055: AB_1079006" "unprognostic (4.37e-2)" "unprognostic (2.20e-2)" "unprognostic (1.84e-1)" "unprognostic (9.57e-3)" "unprognostic (2.70e-3)" "unprognostic (2.09e-1)" "unprognostic (3.03e-2)" "unprognostic (3.66e-1)" "unprognostic (1.69e-1)" "unprognostic (3.29e-1)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.14e-2)" "unprognostic (2.20e-1)" "unprognostic (2.31e-1)" "unprognostic (4.85e-2)" "unprognostic (2.07e-2)" 34.8 94.0 33.5 19.3 41.3 25.0 34.5 37.8 43.3 31.4 43.2 27.9 17.7 29.7 28.9 23.6 28.5 23.7 28.7 32.6 34.8 37.1 40.9 28.4 27.9 38.8 35.5 35.7 39.6 40.2 32.9 20.9 39.3 29.9 16.2 15.6 42.9 20.7 34.6 37.2 30.9 14.9 35.1 38.3 34.8 21.4 35.7 13.3 33.9 16.9 14.4 28.8 26.5 44.5 13.3 21.2 15.3 26.9 135.2 50.3 20.1 38.3 49.6 14.9 28.4 19.1 37.0 8.4 43.0 51.8 22.5 24.0 9.2 22.4 7.6 27.0 20.2 11.3 73.9 33.0 57.6 18.2 43.2 67.3 38.4 14.2 20.3 41.6 27.5 15.2 13.7 48.4 24.6 30.7 8.7 18.7 14.4 33.9 11.8 30.5 12.9 38.6 37.3 17.1 12.0 15.5 38.5 39.2 28.7 8.5 36.9 27.3 27.0 29.8 25.5 24.6 19.1 50.6 40.4 17.7 24.4 15.6 20.3 70.5 77.0 49.5 43.3 74.4 39.6 32.1 36.7 40.8 61.5 31.1 33.4 30.8 32.0 32.6 73.9 52.2 46.9 49.7 33.5 41.3 37.8 43.3 32.6 34.8 38.8 35.5 39.3 35.1 35.7 44.5 39.7 41.7 41.7 17.3 31.9 20.9 26.5 25.4 46.7 15.1 34.0 42.9 9.4 37.1 43.2 20.2 25.0 25.0 34.9 25.8 9.8 27.4 2.6 17.7 29.8 25.6 9.1 9.9 22.7 14.5 20.3 49.7 47.4 23.7 24.6 21.1 30.7 35.2 50.2 8.4 20.5 18.0 14.2 43.4 41.7 4.6 30.1 47.8 33.8 9.4 25.7 31.0 30.9 15.1 32.4 14.8 32.9 17.7 76.1 22.1 32.1 41.7 28.5 24.5 19.7 24.4 22.9 25.4 24.2 48.1 20.3 31.1 30.6 20.5 21.7 24.5 GOLM2 "CASC4, DKFZp459F1927, H63" ENSG00000166734 "Golgi membrane protein 2" Q6P4E1 15 44288719-44415758 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 19.9;Cardiomyocytes: 24.0;Cytotrophoblasts: 16.3;dendritic cells: 16.1;Extravillous trophoblasts: 19.4;Fibroblasts: 18.2;Hofbauer cells: 27.3;Syncytiotrophoblasts: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043015, HPA049488" Enhanced Enhanced "Golgi apparatus" NA NA 1200000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "HPA043015: AB_2678271, HPA049488: AB_2680790" "unprognostic (2.64e-2)" "unprognostic (2.63e-1)" "unprognostic (3.38e-1)" "unprognostic (1.81e-2)" "unprognostic (8.08e-2)" "unprognostic (1.35e-1)" "unprognostic (1.20e-2)" "unprognostic (2.20e-1)" "unprognostic (2.40e-1)" "unprognostic (1.68e-2)" "unprognostic (4.99e-2)" "unprognostic (2.60e-2)" "prognostic favorable (1.45e-5)" "unprognostic (2.15e-1)" "unprognostic (3.56e-2)" "unprognostic (9.65e-2)" "unprognostic (1.12e-1)" 39.5 84.5 48.5 32.4 47.0 16.5 43.2 43.1 59.2 57.9 62.4 45.7 28.8 50.4 53.5 23.7 53.8 50.5 33.1 42.8 52.6 54.0 60.9 40.9 30.8 49.6 51.5 55.3 37.4 82.0 38.7 34.4 46.9 67.5 43.8 33.7 47.8 56.1 22.3 13.2 29.8 44.4 46.7 35.4 49.4 34.6 52.9 28.9 84.6 26.3 29.5 39.2 24.3 52.7 45.0 38.7 51.9 92.6 141.4 121.8 32.0 78.6 125.2 44.9 57.1 19.3 80.0 13.5 106.4 119.3 47.8 53.8 34.4 25.5 48.2 64.6 19.5 21.4 41.8 35.9 65.1 42.5 68.1 72.1 28.3 49.8 38.4 126.8 53.4 34.2 33.0 103.4 56.2 23.2 36.7 33.2 14.8 60.8 27.5 30.5 29.3 43.3 58.8 54.4 23.3 53.2 60.7 57.0 26.6 28.1 64.1 49.2 76.4 78.1 39.8 112.5 69.5 79.0 145.1 27.9 92.6 58.5 51.7 20.9 14.7 20.8 15.2 9.8 16.3 11.9 12.4 15.2 12.0 10.7 9.5 9.9 37.8 10.5 18.2 10.6 13.2 13.6 48.5 47.0 43.1 59.2 42.8 52.6 49.6 51.5 46.9 46.7 52.9 52.7 19.9 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 16.3 16.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 19.4 18.2 0.0 0.0 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 12.7 2.9 0.0 0.0 0.0 GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149865-112215377 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 305.7;liver: 144.1" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Hepatocytes: 184.5;Horizontal cells: 45.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 250.3;Hep G2: 71.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA046339: AB_2679627, HPA060090: AB_2684202" "unprognostic (1.82e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-1)" "unprognostic (4.80e-1)" "unprognostic (2.37e-2)" "unprognostic (5.44e-2)" "prognostic favorable (4.54e-6)" "unprognostic (2.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.37e-1)" 305.7 33.9 14.9 4.8 17.1 3.4 67.7 12.2 14.0 3.0 6.9 6.4 4.0 4.2 75.1 2.9 3.1 6.0 12.3 12.4 13.0 4.4 144.1 4.1 4.6 12.9 16.0 5.3 5.0 4.3 2.1 3.0 12.1 3.9 4.7 5.1 17.2 5.3 8.3 3.2 6.1 4.9 11.5 2.9 4.9 5.6 15.7 3.6 12.4 8.8 4.3 4.8 2.6 10.5 9.9 7.4 9.7 12.9 250.3 9.1 12.7 9.2 10.5 6.6 5.1 17.3 5.7 6.9 5.0 6.5 6.1 12.3 15.5 7.9 12.3 5.0 8.4 6.4 7.9 71.8 7.7 11.2 3.4 43.8 13.1 11.7 23.6 49.7 5.8 9.7 8.5 6.1 7.7 5.6 9.6 8.8 8.1 5.6 10.1 9.7 25.4 5.1 4.3 6.8 4.1 12.1 12.8 6.1 14.5 8.9 6.3 4.0 4.4 7.5 4.6 9.4 14.8 6.1 7.3 14.3 8.8 9.8 5.8 0.0 0.3 0.1 0.7 0.4 0.9 0.5 0.5 0.5 0.4 1.1 0.5 0.9 0.0 0.3 0.3 0.6 0.6 0.3 14.9 17.1 12.2 14.0 12.4 13.0 12.9 16.0 12.1 11.5 15.7 10.5 9.1 9.6 27.1 90.8 5.2 0.4 0.8 1.6 4.6 5.3 8.1 8.4 18.9 20.0 4.3 5.5 10.4 5.2 4.3 1.7 1.9 2.7 0.5 5.1 10.0 5.0 1.2 12.2 8.2 3.3 2.9 5.1 3.6 4.2 2.5 12.7 6.4 184.5 3.1 45.4 9.4 3.0 0.0 9.3 1.0 0.9 5.3 1.9 1.8 10.3 1.4 6.1 3.1 10.1 10.1 3.4 2.7 12.0 6.4 1.1 3.7 3.3 4.7 9.1 6.6 4.3 6.6 4.0 3.2 5.4 0.1 1.9 3.3 8.6 5.0 0.6 GPC6 ENSG00000183098 "Glypican 6" Q9Y625 13 93226807-94408020 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 163.2;Excitatory neurons: 333.6;Inhibitory neurons: 496.1;Oligodendrocyte precursor cells: 691.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 62.5;HSkMC: 70.8;hTERT-RPE1: 64.3;SuSa: 39.5;U-87 MG: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA017671 Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 420000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA017671: AB_1849833" "unprognostic (5.24e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" "unprognostic (9.76e-2)" "unprognostic (1.72e-1)" "unprognostic (5.50e-2)" "unprognostic (1.28e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "unprognostic (2.66e-2)" "unprognostic (2.33e-2)" "unprognostic (3.71e-2)" "unprognostic (2.53e-3)" "unprognostic (6.21e-3)" "unprognostic (7.42e-2)" "unprognostic (3.36e-1)" "unprognostic (3.35e-3)" 9.1 2.2 0.8 8.9 1.9 0.1 2.2 1.7 1.5 3.6 1.1 6.3 2.3 2.4 2.4 5.2 4.1 17.0 6.2 1.3 3.1 7.7 17.7 3.5 0.4 1.7 2.4 7.3 1.6 1.8 2.9 1.3 2.3 6.2 6.5 5.6 3.1 15.1 0.6 1.1 4.3 7.8 2.0 2.2 5.4 2.0 1.9 1.7 1.7 1.9 0.9 11.6 2.4 2.1 0.0 4.7 10.2 4.5 62.5 19.5 0.0 7.2 0.0 4.9 6.4 0.0 0.0 0.2 0.0 16.0 0.0 0.0 5.7 1.2 9.1 0.0 4.1 0.0 0.1 20.2 37.8 0.1 0.1 70.8 0.5 11.7 8.1 64.3 0.0 0.0 0.0 0.1 6.9 0.0 0.0 0.1 6.4 0.0 3.4 0.0 1.6 0.1 5.5 0.0 4.1 16.8 0.0 1.9 0.0 39.5 14.0 0.0 0.0 26.9 22.6 25.4 12.3 15.9 0.1 0.0 52.8 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 1.9 1.7 1.5 1.3 3.1 1.7 2.4 2.3 2.0 1.9 2.1 0.6 0.0 0.5 163.2 0.0 0.6 0.5 0.5 0.6 50.3 0.6 1.9 1.7 4.3 0.7 7.3 10.4 0.2 0.0 0.1 0.0 0.3 6.7 1.6 25.9 1.1 0.0 0.0 333.6 0.0 0.1 31.2 0.0 3.1 0.0 36.0 5.7 41.2 0.5 0.0 496.1 0.1 2.0 1.3 1.0 5.0 4.7 0.5 1.8 31.9 0.0 2.7 0.0 691.6 13.2 0.1 0.0 1.9 0.1 1.6 0.0 14.5 0.0 115.0 0.0 34.4 20.9 4.2 2.7 0.5 0.4 0.1 0.7 11.9 0.1 0.2 GPD1 ENSG00000167588 "Glycerol-3-phosphate dehydrogenase 1" P21695 12 50103982-50111313 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 609.9;skeletal muscle: 577.1" "Group enriched" "Detected in many" 4 "Hepatocytes: 99.1;Proximal enterocytes: 247.0;Proximal tubular cells: 298.4" "Cancer enhanced" "Detected in many" "liver cancer: 18.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC diff: 134.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044620, HPA058621" Enhanced NA NA 4700000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044620: AB_10796803, HPA058621: " "unprognostic (2.65e-2)" "unprognostic (5.60e-2)" "unprognostic (3.28e-2)" "unprognostic (3.37e-2)" "unprognostic (3.26e-1)" "unprognostic (2.54e-1)" "unprognostic (1.45e-3)" "unprognostic (7.19e-2)" "unprognostic (9.42e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (3.24e-1)" "unprognostic (1.37e-1)" "unprognostic (9.58e-2)" "unprognostic (3.37e-1)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" 609.9 4.7 9.1 1.6 16.8 0.2 229.2 22.7 12.8 0.3 5.5 6.4 76.4 0.2 5.3 4.9 0.5 16.6 9.2 10.1 14.2 149.3 147.6 18.4 1.0 32.6 18.3 0.3 7.2 13.0 1.3 0.0 26.5 1.3 3.3 1.0 33.0 1.3 577.1 10.2 76.9 1.3 32.7 0.4 3.3 0.8 18.4 1.5 2.7 215.7 0.4 4.1 1.0 49.4 0.1 0.2 0.1 0.1 134.0 0.0 0.3 0.1 0.0 0.0 0.0 27.0 0.1 0.4 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.1 0.6 25.2 0.0 0.2 0.0 0.3 0.2 0.1 0.3 0.1 0.0 0.7 0.7 0.3 0.0 0.2 0.1 0.4 0.1 3.7 0.0 0.2 0.2 30.2 0.2 0.0 0.6 0.2 0.0 1.5 1.0 0.0 1.8 0.0 0.0 0.0 0.3 0.2 0.1 0.6 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 16.8 22.7 12.8 10.1 14.2 32.6 18.3 26.5 32.7 18.4 49.4 3.4 3.2 3.2 0.0 2.4 0.0 0.2 0.3 0.6 3.2 3.4 3.7 5.8 11.5 1.8 5.5 8.4 0.0 0.0 3.0 43.0 0.9 0.1 0.5 0.1 0.2 1.2 5.3 0.2 0.7 0.0 0.8 4.1 0.2 0.0 0.1 1.1 99.1 2.3 3.3 0.2 9.7 0.0 1.0 0.4 0.0 0.0 5.2 1.8 0.0 1.0 2.8 0.0 0.0 4.0 0.6 8.0 0.0 0.0 0.1 247.0 298.4 0.4 1.7 0.0 7.0 1.1 0.0 0.0 0.8 0.4 0.0 1.2 0.0 10.6 0.2 GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 581.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 327.1;Fibroblasts: 285.8;Hofbauer cells: 814.1;Macrophages: 328.9;Melanocytes: 597.7;Suprabasal keratinocytes: 359.7" "Cancer enhanced" "Detected in all" "melanoma: 354.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cell line enriched" "Detected in many" 6 "ASC diff: 5015.0" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 33000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.65e-2)" "unprognostic (1.82e-1)" "unprognostic (5.14e-2)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (3.89e-2)" "unprognostic (7.13e-2)" "unprognostic (2.79e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (2.08e-3)" "unprognostic (1.24e-2)" "unprognostic (3.46e-2)" "unprognostic (4.82e-1)" "unprognostic (6.95e-2)" 152.9 25.9 20.9 41.7 20.9 6.6 135.6 19.0 70.9 303.9 77.6 78.8 22.5 180.9 43.8 111.8 72.8 270.7 323.5 21.2 23.1 32.7 52.5 215.8 169.0 32.2 21.5 77.7 20.6 15.3 12.8 148.6 31.0 30.4 92.9 2.9 66.1 55.8 15.4 581.2 48.5 151.5 27.3 31.9 37.1 26.2 34.6 89.5 51.5 72.4 103.4 190.9 151.0 66.5 19.2 0.8 0.1 0.6 5015.0 908.0 0.4 33.6 564.1 27.9 116.2 0.2 0.8 0.7 1.4 109.5 49.1 118.3 0.7 0.7 14.2 1.3 1.3 0.1 0.9 2.5 61.5 1.5 0.6 630.3 134.8 46.3 4.7 734.9 0.3 1.4 0.3 0.6 150.2 3.5 0.7 0.7 0.6 0.5 0.5 0.4 1.4 7.6 71.2 443.4 2.4 0.6 0.1 175.6 841.5 1.3 2.3 2.8 0.1 163.0 17.8 297.8 5.5 5.1 8.6 1.2 56.3 2.6 166.1 0.6 2.1 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.1 0.1 0.4 0.0 0.5 20.9 20.9 19.0 70.9 21.2 23.1 32.2 21.5 31.0 27.3 34.6 66.5 18.0 19.2 24.3 0.3 3.2 327.1 7.1 58.5 150.2 0.4 6.6 24.5 204.2 2.8 16.0 75.4 0.0 7.2 2.2 0.1 3.9 0.6 3.0 2.5 44.0 15.0 0.0 0.0 0.5 0.8 4.6 285.8 12.2 2.5 22.7 0.1 4.6 5.1 814.1 1.7 1.2 0.0 12.2 188.4 100.7 5.5 129.8 328.9 597.7 12.2 3.2 0.2 1.0 55.8 0.1 0.6 0.0 108.0 10.2 1.9 0.0 1.2 3.4 0.6 0.0 20.6 53.4 3.9 1.4 65.3 359.7 28.9 5.7 0.1 0.0 11.9 GPX3 ENSG00000211445 "Glutathione peroxidase 3" P22352 5 151020438-151028992 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 11673.5" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 20125.9" "Cancer enhanced" "Detected in all" "renal cancer: 605.6;thyroid cancer: 856.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 20.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.7" "Cell line enriched" "Detected in many" 12 "ASC diff: 7677.4" "Region enhanced" "Detected in all" "hypothalamus: 239.5" "Low region specificity" "Detected in all" CAB069456 Approved "Secreted to blood" NA NA 5090000000 6200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB069456: AB_1616682" "unprognostic (4.03e-1)" "unprognostic (7.35e-2)" "unprognostic (5.05e-3)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "unprognostic (8.13e-2)" "unprognostic (1.39e-2)" "unprognostic (1.62e-1)" "unprognostic (5.75e-3)" "unprognostic (2.70e-3)" "unprognostic (8.17e-3)" "unprognostic (1.14e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (2.14e-1)" "unprognostic (5.11e-2)" "unprognostic (1.26e-1)" 4524.7 443.8 57.8 75.4 68.3 7.9 3188.6 62.7 73.8 917.6 578.2 741.2 88.3 416.0 90.7 568.6 1038.4 136.4 2362.4 68.2 117.5 11673.5 986.3 2471.8 133.2 317.7 104.5 517.8 257.0 112.4 793.7 592.2 136.6 557.5 93.4 4204.9 481.4 140.0 847.9 669.7 720.6 61.0 67.5 555.7 641.1 80.4 135.8 26.8 3627.5 458.9 44.9 1196.7 891.7 70.3 2.2 10.0 8.5 2.7 7677.4 6.7 9.2 3.5 0.8 7.9 2.4 177.5 3.9 1.1 214.1 5.6 3.2 2.8 39.6 433.2 6.0 6.1 2.5 1.9 4.3 195.0 294.7 0.5 4.3 649.1 41.2 0.2 1.0 10.6 11.3 1.2 1.2 0.3 11.0 31.4 0.5 1.2 13.8 0.8 0.2 1.0 5.2 1.7 74.1 4.3 11.3 11.4 1.2 31.6 1.9 33.6 43.5 2.1 2.5 2.3 19.6 3.7 1.0 2.7 15.6 2.5 7.0 3.0 0.6 0.0 4.3 0.1 0.0 1.6 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 20.7 0.0 0.2 0.0 0.0 1.6 57.8 68.3 62.7 73.8 68.2 117.5 317.7 104.5 136.6 67.5 135.8 70.3 353.6 9.6 33.7 1.0 106.8 18.5 86.9 94.8 1.2 26.3 31.7 5.5 639.8 18.6 58.3 649.2 43.8 713.8 2.2 2.3 1772.6 5.5 2.9 48.1 71.1 144.6 45.6 24.0 4.0 48.2 1191.3 514.0 50.0 627.9 11.4 274.9 735.3 228.4 151.5 16.8 0.4 5.9 91.6 47.9 86.7 17.5 446.7 160.2 23.2 3.7 0.7 5019.8 0.0 0.0 0.3 9.9 13.8 41.0 2.2 141.8 0.5 20125.9 39.1 86.8 683.7 131.6 264.6 7.1 10.3 13.9 21.6 1767.7 68.3 1.0 1.3 34.3 GPX4 "MCSP, PHGPx" ENSG00000167468 "Glutathione peroxidase 4" P36969 19 1103926-1106791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Oxidoreductase, Peroxidase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 18580.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008630, HPA047224, HPA058546" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "CAB008630: AB_1616685, HPA047224: AB_2679990, HPA058546: AB_2683749" "unprognostic (8.42e-3)" "prognostic favorable (7.18e-4)" "unprognostic (8.14e-3)" "prognostic favorable (1.84e-5)" "unprognostic (1.00e-1)" "unprognostic (8.72e-2)" "unprognostic (2.53e-3)" "unprognostic (8.49e-2)" "unprognostic (2.69e-2)" "unprognostic (1.47e-1)" "prognostic favorable (7.72e-4)" "unprognostic (1.29e-1)" "prognostic favorable (8.61e-4)" "unprognostic (1.61e-2)" "unprognostic (2.20e-1)" "unprognostic (6.67e-3)" "unprognostic (2.96e-2)" 927.8 535.3 415.1 127.4 428.7 178.0 733.3 440.7 519.1 280.8 478.7 249.0 259.0 188.4 318.9 220.4 199.2 196.6 426.0 419.2 450.3 536.5 687.8 307.9 216.4 430.9 448.3 260.3 157.9 285.5 398.4 147.2 454.1 322.1 110.9 167.5 304.9 193.8 672.3 290.4 236.2 87.9 418.2 213.2 219.0 1403.5 444.0 158.7 291.5 399.7 182.5 319.0 245.2 429.1 258.1 286.8 405.8 863.0 1202.1 706.0 449.3 199.3 713.5 371.1 375.9 590.5 339.8 92.8 211.8 405.8 313.5 283.1 239.7 289.3 180.5 522.3 436.5 175.0 246.9 849.2 697.4 207.6 269.4 707.3 432.1 188.3 314.7 665.9 527.1 317.5 249.4 225.7 311.1 660.4 353.8 354.9 386.2 569.7 458.9 482.8 55.3 271.3 408.9 629.9 348.3 220.6 390.5 366.1 422.1 246.7 358.1 498.0 450.9 392.3 257.4 680.6 254.6 786.5 582.0 224.3 369.4 412.2 230.9 578.9 539.6 564.4 219.8 405.4 256.9 352.7 319.7 230.7 404.0 309.9 339.4 245.0 265.1 196.6 462.2 278.8 310.3 841.7 415.1 428.7 440.7 519.1 419.2 450.3 430.9 448.3 454.1 418.2 444.0 429.1 415.9 179.5 189.7 21.2 281.7 510.0 525.8 1188.1 512.2 332.2 845.1 868.2 264.6 316.0 600.6 472.6 98.0 562.5 231.3 479.1 1592.6 515.8 4209.7 546.8 326.3 268.7 397.1 215.0 24.5 368.7 1327.3 536.1 99.9 442.3 346.1 242.6 322.0 826.2 1184.1 208.6 33.1 328.7 671.4 583.1 1304.8 18580.2 384.9 735.2 677.7 21.5 1786.8 502.6 192.6 13.6 35.4 484.0 507.9 312.9 189.2 694.7 1861.9 3024.7 800.9 246.0 243.3 244.6 587.1 1310.8 202.4 357.7 467.0 978.1 281.0 186.7 336.4 662.6 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 GSTM2 GST4 ENSG00000213366 "Glutathione S-transferase mu 2" P28161 1 109668022-109709551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 61.0;Plasma cells: 28.4;Squamous epithelial cells: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 116.0;HSkMC: 115.6" "Low region specificity" "Detected in all" "CAB040547, HPA055972, HPA055973" Approved Supported Vesicles,Cytosol NA NA 1200000 "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol Vesicles "CAB040547: , HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (2.51e-3)" "unprognostic (1.28e-1)" "unprognostic (2.04e-2)" "unprognostic (2.57e-2)" "unprognostic (2.20e-1)" "unprognostic (5.04e-2)" "unprognostic (7.31e-2)" "prognostic favorable (9.70e-5)" "unprognostic (1.51e-2)" "unprognostic (7.43e-2)" "unprognostic (1.80e-3)" "unprognostic (2.94e-1)" "unprognostic (1.48e-3)" "unprognostic (1.07e-2)" "unprognostic (1.87e-1)" "unprognostic (2.32e-1)" "unprognostic (2.14e-1)" 73.7 84.4 92.3 11.9 109.9 10.7 81.2 86.7 104.6 165.9 111.5 115.2 26.3 70.6 43.7 61.6 102.7 22.0 99.7 93.5 104.7 86.8 35.6 45.2 14.3 94.3 97.1 240.9 54.5 53.6 113.7 9.3 91.9 159.0 17.7 25.1 55.2 80.7 218.4 88.2 65.5 34.2 93.9 52.6 88.3 41.9 105.2 15.9 97.9 108.4 12.6 108.3 144.5 90.6 0.0 3.5 37.8 38.9 44.0 116.0 7.2 24.5 42.6 22.1 28.0 6.7 0.0 0.7 25.5 61.1 18.0 0.2 3.1 0.2 28.6 1.5 0.8 14.0 0.4 9.3 29.6 1.1 25.2 115.6 1.0 32.7 0.0 58.5 16.1 11.6 4.2 0.7 48.5 0.3 19.5 24.6 6.7 0.7 32.4 23.8 0.1 0.2 6.6 0.5 8.1 18.7 0.0 1.0 13.0 21.7 38.6 7.0 0.2 24.3 1.2 35.3 1.9 11.9 19.0 1.3 36.7 0.5 0.3 1.8 3.8 29.6 3.1 6.3 3.1 8.8 8.8 3.4 23.0 6.2 34.4 15.1 2.2 18.0 4.1 29.8 9.4 10.8 92.3 109.9 86.7 104.6 93.5 104.7 94.3 97.1 91.9 93.9 105.2 90.6 2.0 0.0 4.8 16.0 4.5 4.8 2.4 0.9 20.5 1.5 4.5 4.3 61.0 2.8 11.5 3.7 0.0 0.5 6.1 0.4 0.0 0.2 1.9 2.8 10.3 5.8 0.0 10.9 1.5 0.0 0.2 19.2 14.8 2.7 2.5 4.4 1.8 0.8 1.5 3.3 2.6 1.3 2.0 0.8 2.3 10.4 15.5 3.4 5.4 11.2 0.7 7.2 8.2 12.5 0.7 0.1 0.0 10.5 28.4 0.8 0.4 1.2 9.9 0.3 6.6 5.6 13.6 0.3 0.8 27.0 2.8 0.5 5.1 4.0 0.7 1.6 GTF2A1L ALF ENSG00000242441 "General transcription factor IIA subunit 1 like" Q9UNN4 2 48617798-48733148 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 60.0" "Cell type enhanced" "Detected in some" "Early spermatids: 9.2;Late spermatids: 2.3;Spermatocytes: 5.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.6;hTERT-RPE1: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (3.59e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-1)" "unprognostic (4.77e-1)" "unprognostic (5.02e-2)" 2.1 0.5 0.5 0.0 0.5 0.0 1.2 1.4 0.8 2.9 0.7 8.7 0.4 4.2 0.4 0.7 2.9 1.1 0.8 0.4 0.6 1.1 0.2 1.1 0.2 3.4 1.0 2.1 0.2 0.0 0.5 0.2 2.6 2.1 0.1 0.1 0.2 0.2 0.6 0.4 1.7 0.6 2.0 1.3 2.6 60.0 0.8 0.1 0.5 0.1 0.0 4.2 1.6 2.2 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 1.4 0.8 0.4 0.6 3.4 1.0 2.6 2.0 0.8 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 H6PD "GDH, H6PDH" ENSG00000049239 "Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase" O95479 1 9234774-9271337 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 94.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 164.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 68.9;ASC TERT1: 78.9;HSkMC: 77.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004824, HPA005440" Approved Uncertain Cytosol "Intracellular and membrane" NA NA 140000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA004824: AB_1079037, HPA005440: AB_1079036" "unprognostic (4.83e-3)" "unprognostic (3.91e-2)" "unprognostic (1.18e-1)" "unprognostic (3.49e-1)" "unprognostic (5.53e-3)" "unprognostic (2.86e-2)" "unprognostic (8.35e-2)" "unprognostic (5.18e-2)" "unprognostic (9.73e-2)" "unprognostic (1.26e-3)" "unprognostic (2.16e-2)" "unprognostic (7.35e-3)" "unprognostic (8.20e-2)" "unprognostic (3.61e-1)" "unprognostic (1.30e-1)" "unprognostic (8.65e-2)" "unprognostic (1.95e-1)" 29.0 30.5 7.5 12.6 11.6 9.7 23.0 8.2 9.0 22.6 18.8 15.1 11.2 25.7 14.4 13.5 28.3 12.6 18.9 6.4 7.8 11.5 94.5 20.3 12.4 14.4 10.8 44.9 18.9 10.6 12.7 14.1 11.4 19.5 9.1 4.2 56.2 13.1 48.3 35.7 16.8 16.6 9.6 14.5 18.7 8.1 11.4 13.1 14.7 21.0 11.4 16.7 16.5 10.9 9.9 8.0 6.8 25.5 68.9 78.9 6.4 9.8 24.0 7.1 10.9 1.5 20.1 10.9 11.2 15.3 9.1 10.3 1.8 4.8 10.3 32.8 2.2 0.0 2.8 6.7 38.6 3.5 4.1 77.7 9.1 17.2 11.1 15.6 32.9 5.9 2.9 18.2 14.0 5.7 3.9 8.2 3.7 7.5 4.6 1.2 0.9 9.3 9.1 4.0 2.3 12.0 12.9 10.0 12.0 4.7 7.5 17.4 32.9 24.3 3.9 6.2 2.8 24.1 7.6 2.5 40.8 15.6 15.7 1.6 2.3 0.3 1.6 2.4 1.3 1.3 1.2 1.5 1.0 1.6 1.2 1.1 1.5 1.2 2.3 1.4 1.1 1.5 7.5 11.6 8.2 9.0 6.4 7.8 14.4 10.8 11.4 9.6 11.4 10.9 24.1 25.6 29.5 17.9 10.1 14.3 13.2 16.9 18.8 19.6 10.3 8.3 17.5 58.6 18.8 20.2 27.1 11.2 9.1 16.6 0.0 22.9 0.8 11.2 36.0 19.8 7.8 9.0 8.4 21.3 8.5 33.6 5.6 15.5 3.8 29.9 19.6 164.0 12.1 16.8 9.1 15.1 8.2 25.4 11.4 2.9 48.1 14.2 12.4 13.1 51.6 10.4 19.6 16.6 18.6 20.0 17.0 36.9 4.5 17.2 23.1 7.4 19.1 10.9 0.0 50.5 11.7 4.6 5.5 10.5 12.8 5.9 11.6 26.1 23.6 14.2 HABP4 "IHABP4, SERBP1L" ENSG00000130956 "Hyaluronan binding protein 4" Q5JVS0 9 96450169-96491336 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.3" "Group enriched" "Detected in many" 10 "Early spermatids: 224.6;Late spermatids: 808.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.9;T-cells: 1.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055969, HPA062366" Enhanced Supported "Nuclear membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" Cytosol "HPA055969: AB_2682991, HPA062366: " "unprognostic (1.67e-1)" "unprognostic (7.99e-2)" "unprognostic (2.12e-3)" "unprognostic (2.40e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (1.36e-2)" "unprognostic (3.63e-2)" "unprognostic (3.49e-1)" "unprognostic (2.42e-2)" "unprognostic (1.75e-3)" "unprognostic (1.36e-1)" "prognostic favorable (1.10e-7)" "unprognostic (2.25e-1)" "unprognostic (1.40e-1)" "unprognostic (4.93e-2)" "unprognostic (3.62e-2)" 21.9 12.8 62.7 7.0 70.1 1.8 16.8 55.1 73.3 16.1 40.8 19.2 3.0 13.5 7.0 7.6 13.5 8.8 28.1 62.3 63.9 27.0 7.6 10.8 8.3 66.2 65.4 15.6 6.6 12.9 22.6 3.5 66.1 12.5 4.2 16.0 6.2 11.1 16.8 9.5 10.4 9.7 59.5 7.5 12.5 43.9 61.3 4.6 13.7 13.4 5.3 18.4 13.0 68.9 14.8 16.6 20.6 22.3 44.7 37.9 14.6 19.5 21.8 14.5 15.7 24.9 24.0 7.5 9.4 29.4 45.9 10.6 17.4 3.7 11.6 9.0 10.3 2.9 7.8 42.0 22.7 0.7 3.0 15.5 6.7 16.5 13.0 21.9 10.4 8.4 3.4 21.6 26.4 15.2 0.3 4.6 9.6 20.5 15.8 7.6 17.9 0.3 24.8 6.4 13.0 8.8 10.6 6.2 32.5 15.2 4.5 3.2 17.8 19.8 4.6 36.6 16.8 13.2 14.0 3.3 15.9 5.9 29.8 0.0 0.0 0.0 0.5 0.1 0.5 1.9 1.6 1.3 0.0 1.1 1.1 1.1 0.1 0.4 0.3 0.0 1.3 0.2 62.7 70.1 55.1 73.3 62.3 63.9 66.2 65.4 66.1 59.5 61.3 68.9 22.2 0.0 7.4 27.1 5.9 11.5 10.8 0.9 4.0 22.6 3.8 6.9 11.0 14.3 5.5 18.4 0.0 2.5 5.5 0.9 17.6 4.7 224.6 7.3 9.0 14.6 13.1 0.8 47.4 5.8 7.4 13.3 1.5 8.1 1.3 13.0 15.0 6.3 6.6 23.5 33.2 0.9 4.1 1.3 9.3 808.8 13.7 6.0 17.8 10.3 2.7 22.2 3.1 18.6 37.5 6.3 0.0 23.7 5.1 10.0 1.1 43.7 1.8 15.6 6.6 5.8 26.4 26.8 15.4 0.9 8.0 1.4 13.3 3.0 1.3 6.0 HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 502.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 470000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" 105.0 125.3 57.7 31.1 60.7 46.3 94.9 65.0 69.6 72.6 59.1 108.4 115.0 61.8 30.7 90.1 60.1 32.4 330.2 52.8 61.9 99.0 156.7 66.9 35.3 64.4 62.2 77.8 101.4 95.0 57.4 39.2 64.2 60.2 76.1 14.9 77.9 33.4 502.5 95.7 106.2 57.4 61.8 68.4 93.8 49.0 62.4 46.7 59.5 300.7 58.5 79.1 73.6 67.2 105.7 88.1 58.4 90.8 221.1 139.9 51.5 80.6 84.7 78.5 67.7 114.7 104.1 71.7 50.2 138.4 78.6 66.8 103.4 152.6 72.5 139.1 103.6 103.3 86.2 197.9 73.3 132.2 69.2 142.7 101.6 112.4 109.3 82.8 127.7 70.4 140.2 133.2 101.1 128.2 63.4 137.7 50.1 77.5 134.1 52.9 128.5 143.7 90.3 125.3 41.9 85.1 94.6 104.6 102.4 44.5 52.2 125.8 127.1 48.8 70.7 69.9 58.0 44.8 86.5 113.4 77.6 150.2 56.2 22.5 84.0 33.5 31.8 92.3 39.1 40.5 36.8 38.7 80.8 31.2 42.6 40.1 20.9 38.8 86.1 31.3 50.9 89.9 57.7 60.7 65.0 69.6 52.8 61.9 64.4 62.2 64.2 61.8 62.4 67.2 122.4 89.8 99.0 47.0 101.2 89.0 137.5 139.9 97.3 35.6 89.7 96.4 349.9 82.9 128.0 77.3 52.1 182.0 95.1 242.1 131.0 120.8 39.2 73.3 121.1 99.1 91.4 155.9 22.8 108.5 94.7 96.1 100.4 85.5 139.9 140.3 84.3 185.1 163.0 20.2 28.2 156.5 89.5 136.8 106.0 74.3 92.6 145.0 81.8 12.2 170.7 65.4 93.7 30.7 37.4 90.0 195.6 84.2 90.4 76.2 527.4 182.5 84.8 62.3 52.6 129.9 109.6 147.9 54.9 136.5 103.3 129.2 100.5 154.7 216.7 104.4 HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290465 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 793.3;skeletal muscle: 950.6;tongue: 1097.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1167.5;Distal tubular cells: 520.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037539, HPA037540, HPA066099" Enhanced Supported Mitochondria No No 61000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA037539: AB_10671374, HPA037540: AB_2675531, HPA066099: AB_2685618" "unprognostic (5.15e-2)" "unprognostic (8.72e-2)" "unprognostic (8.21e-2)" "unprognostic (8.67e-2)" "unprognostic (7.70e-2)" "unprognostic (2.59e-2)" "unprognostic (7.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (2.03e-1)" "unprognostic (8.94e-2)" "prognostic favorable (1.37e-9)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (2.88e-1)" "unprognostic (9.68e-2)" 127.0 224.7 120.6 51.1 135.4 58.8 91.3 146.4 138.1 65.2 128.0 110.7 224.2 55.9 73.7 101.3 68.8 64.3 793.3 109.0 138.1 231.4 324.8 64.7 54.9 135.9 141.6 78.4 83.7 209.5 48.1 65.6 139.6 77.1 113.2 63.0 104.8 75.0 950.6 74.4 184.4 79.0 141.4 75.8 109.0 67.1 143.3 53.1 90.8 1097.1 62.5 89.2 64.1 152.8 108.2 83.2 56.6 102.2 342.1 190.1 57.9 89.0 134.6 89.0 86.8 100.5 101.7 53.9 60.8 145.3 100.1 82.8 95.2 124.8 109.2 121.1 83.1 123.6 44.9 194.2 145.9 100.6 90.0 183.7 201.6 92.7 149.0 151.0 168.2 81.0 105.2 83.9 189.5 78.0 57.1 190.7 39.8 160.2 89.0 61.7 188.3 103.2 183.3 148.9 27.2 93.7 151.7 169.8 239.5 68.5 105.4 177.9 118.0 83.5 86.9 79.3 65.1 62.6 101.1 94.7 95.5 158.4 84.4 95.7 168.1 66.4 45.2 150.3 57.6 65.5 61.3 56.6 154.2 49.7 55.8 51.3 72.7 88.2 123.3 51.8 94.7 135.6 120.6 135.4 146.4 138.1 109.0 138.1 135.9 141.6 139.6 141.4 143.3 152.8 106.5 48.1 36.5 63.0 48.3 62.1 136.5 183.3 49.5 29.3 49.5 52.3 1167.5 104.4 107.7 97.5 56.3 227.9 42.4 129.5 520.4 124.0 93.4 59.5 49.0 75.2 74.9 85.2 32.7 57.2 75.2 79.5 53.0 60.2 62.8 94.2 69.9 277.6 139.6 13.5 33.0 93.4 114.0 98.1 67.4 99.7 56.5 78.1 88.9 27.2 110.2 65.0 32.0 35.2 47.5 58.4 134.8 62.8 37.1 60.5 376.0 321.1 73.5 80.0 72.3 72.9 80.7 120.4 49.4 53.8 54.7 186.6 45.2 194.0 113.5 110.3 HCFC2 HCF-2 ENSG00000111727 "Host cell factor C2" Q9Y5Z7 12 104064531-104106524 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 250.3;Spermatocytes: 130.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006227 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA006227: AB_1079042" "unprognostic (4.22e-3)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (7.66e-2)" "unprognostic (3.15e-2)" "unprognostic (2.11e-2)" "unprognostic (1.46e-1)" "unprognostic (1.07e-2)" "unprognostic (1.59e-1)" "unprognostic (1.43e-2)" "unprognostic (2.71e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-3)" "unprognostic (1.16e-2)" "unprognostic (2.24e-1)" "unprognostic (1.19e-2)" "unprognostic (7.23e-2)" 6.3 6.7 3.8 3.6 5.2 2.7 5.1 4.4 5.4 7.4 2.0 9.2 5.2 7.9 5.0 6.2 5.3 5.7 5.1 3.7 4.2 5.7 7.3 4.7 4.6 4.9 5.0 7.8 6.0 6.7 4.1 6.4 4.8 7.2 4.3 8.0 4.5 9.4 9.7 4.4 5.0 7.2 4.7 5.1 5.2 9.5 4.6 5.2 6.9 11.2 3.7 5.9 6.0 6.6 2.0 2.3 2.3 2.0 12.7 12.5 1.7 9.1 4.1 6.8 3.9 1.1 0.9 2.1 3.1 7.1 2.5 2.2 2.9 1.6 7.3 3.5 2.8 2.1 2.3 1.0 8.5 1.7 3.3 7.8 4.3 4.2 3.5 9.8 5.3 3.1 2.5 4.2 12.3 1.8 3.1 4.0 0.5 1.3 4.7 2.5 7.6 1.3 3.1 1.4 3.3 2.5 4.4 3.2 3.5 1.5 5.0 1.9 8.0 10.7 1.4 5.6 3.1 5.3 1.7 1.8 5.1 2.3 4.4 0.4 0.6 0.9 0.8 1.1 0.9 0.5 0.7 0.9 0.7 0.5 0.8 0.9 0.1 0.8 1.8 0.4 0.9 0.5 3.8 5.2 4.4 5.4 3.7 4.2 4.9 5.0 4.8 4.7 4.6 6.6 19.3 12.8 14.1 18.9 10.0 8.0 6.6 5.4 8.6 19.6 6.1 5.0 12.5 1.5 9.6 5.5 20.9 5.0 8.8 7.4 9.8 6.2 250.3 7.9 18.5 14.4 8.4 7.4 31.8 3.3 5.0 16.0 6.6 6.5 17.1 9.8 15.7 11.5 7.4 23.5 33.9 4.7 8.2 11.4 5.7 59.4 21.8 8.6 7.2 16.9 9.3 13.7 7.2 30.7 45.6 3.1 6.0 27.8 12.2 2.7 7.7 8.6 10.4 22.2 13.1 18.7 17.4 130.9 16.4 8.5 7.2 10.8 11.3 17.9 3.8 3.3 HEBP1 "HBP, HEBP" ENSG00000013583 "Heme binding protein 1" Q9NRV9 12 12974870-13000265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 242.9" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 837.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056417, HPA075277" Approved Approved Nucleoplasm,Vesicles NA NA 290000 "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Vesicles Nucleoplasm "HPA056417: AB_2683122, HPA075277: AB_2686741" "unprognostic (1.65e-1)" "unprognostic (2.31e-2)" "unprognostic (9.28e-2)" "unprognostic (5.67e-3)" "unprognostic (4.45e-3)" "unprognostic (5.42e-3)" "unprognostic (2.70e-1)" "unprognostic (2.44e-1)" "unprognostic (6.04e-2)" "unprognostic (3.50e-2)" "unprognostic (1.94e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-3)" "unprognostic (5.71e-2)" "unprognostic (1.64e-1)" "unprognostic (4.02e-2)" "unprognostic (4.43e-2)" 72.5 108.1 43.1 21.0 49.6 57.9 66.6 48.0 46.0 54.8 47.3 44.5 242.9 43.8 17.4 42.6 49.9 41.4 58.5 40.9 46.0 69.1 145.8 54.6 28.2 52.5 46.5 80.0 75.9 50.2 27.8 34.6 49.9 42.4 21.7 15.2 43.7 36.8 39.3 59.6 165.7 38.7 49.9 58.5 45.1 29.8 46.8 19.5 122.6 37.7 21.4 51.2 50.3 53.5 74.2 46.2 29.3 54.8 229.6 167.6 20.5 65.0 91.0 60.2 79.7 29.8 26.6 21.2 25.2 128.8 51.9 64.7 37.6 54.2 69.1 3.0 30.0 12.0 51.0 74.2 159.1 22.3 11.3 134.7 47.9 80.7 101.9 187.0 124.3 25.1 13.6 19.4 103.9 48.1 18.3 34.9 42.5 71.5 30.0 40.2 85.3 22.1 50.8 74.1 16.6 14.8 85.6 41.1 86.5 84.2 21.3 33.6 140.2 45.7 53.1 72.6 36.2 16.4 14.4 7.9 73.2 38.5 18.8 15.6 65.7 17.2 9.6 49.4 13.5 11.5 16.5 10.4 51.2 11.8 20.6 12.1 21.0 18.7 69.8 25.3 9.7 25.9 43.1 49.6 48.0 46.0 40.9 46.0 52.5 46.5 49.9 49.9 46.8 53.5 120.1 54.5 21.3 2.0 14.9 37.5 56.2 38.3 39.9 43.0 73.3 95.8 26.7 115.8 19.8 57.0 4.2 36.2 14.5 56.5 99.7 89.5 33.8 8.6 27.4 80.4 20.4 174.4 1.5 100.3 27.1 68.6 28.5 14.6 1.3 31.6 162.4 121.7 82.0 6.7 1.7 45.3 18.3 85.4 43.1 13.0 89.2 53.7 62.2 0.0 78.1 44.2 10.3 4.5 3.5 71.1 90.5 94.0 8.0 79.8 837.6 93.0 7.0 6.7 52.6 35.7 40.8 13.8 7.5 44.5 36.1 26.3 14.5 84.3 93.6 54.3 HGSNAT "FLJ32731, HGNAT, TMEM76" ENSG00000165102 "Heparan-alpha-glucosaminide N-acetyltransferase" Q68CP4 8 43140464-43202855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant, Mucopolysaccharidosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029578 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "HPA029578: AB_10602423" "unprognostic (5.35e-2)" "unprognostic (4.61e-2)" "unprognostic (4.31e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (5.46e-4)" "unprognostic (3.94e-3)" "unprognostic (1.10e-1)" "unprognostic (6.54e-3)" "unprognostic (5.02e-2)" "prognostic favorable (6.33e-5)" "unprognostic (2.55e-2)" "unprognostic (5.48e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "unprognostic (1.55e-1)" "unprognostic (1.72e-1)" "unprognostic (3.45e-2)" 32.3 20.0 13.1 17.5 13.0 21.7 27.8 10.6 13.5 35.0 13.8 25.4 18.4 30.1 30.6 24.0 29.0 25.9 23.3 13.3 17.6 20.0 26.6 24.5 11.7 13.3 12.0 35.9 29.9 22.7 30.7 28.4 13.2 26.9 17.2 12.5 25.9 23.3 14.4 35.4 20.9 25.1 11.4 17.6 23.2 7.6 15.8 11.3 26.9 17.6 15.7 25.2 28.7 13.0 27.4 36.0 8.9 18.0 71.7 53.8 13.3 30.5 36.2 21.8 19.3 5.1 39.2 14.8 20.5 42.9 15.2 15.5 4.0 18.5 12.7 6.4 6.9 16.3 22.2 8.1 23.0 3.7 2.5 36.2 25.9 11.7 24.9 34.5 39.2 7.0 7.5 22.1 40.4 10.0 14.8 7.2 8.0 16.3 5.4 1.6 16.1 7.7 36.1 22.8 4.7 14.0 39.0 12.6 17.4 19.0 43.7 20.9 46.3 33.2 5.4 20.9 12.7 17.9 18.2 6.1 26.8 6.3 20.8 0.2 8.8 9.4 2.7 5.4 3.0 1.9 2.3 2.8 15.8 2.1 1.7 1.9 3.2 8.8 8.6 2.0 1.7 5.0 13.1 13.0 10.6 13.5 13.3 17.6 13.3 12.0 13.2 11.4 15.8 13.0 39.1 16.0 31.9 48.0 26.7 18.0 19.5 22.6 8.6 50.6 23.9 21.7 10.5 28.6 17.8 51.5 50.1 39.2 30.1 27.2 3.9 26.7 0.5 23.5 42.1 37.8 24.1 15.3 61.8 28.1 39.4 34.3 32.6 36.5 8.2 51.2 49.6 23.5 29.2 25.2 76.3 28.0 18.3 34.3 58.8 3.2 35.1 43.3 19.6 44.0 33.5 13.5 34.0 50.8 43.8 29.9 17.0 31.6 19.8 20.7 31.4 9.9 23.5 39.6 26.3 30.2 28.2 1.1 3.0 22.3 21.2 30.1 25.0 37.4 21.7 17.7 HIPK3 "DYRK6, FIST3, PKY, YAK1" ENSG00000110422 "Homeodomain interacting protein kinase 3" Q9H422 11 33256672-33357023 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028069 Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Nuclear bodies" "HPA028069: AB_10601815" "unprognostic (2.41e-3)" "unprognostic (1.02e-1)" "unprognostic (4.61e-1)" "unprognostic (5.74e-2)" "unprognostic (2.09e-1)" "unprognostic (1.78e-2)" "unprognostic (1.63e-1)" "unprognostic (7.29e-2)" "unprognostic (1.61e-1)" "unprognostic (2.78e-1)" "unprognostic (2.18e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-3)" "unprognostic (7.89e-3)" "unprognostic (1.80e-1)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" 57.8 21.5 29.5 25.3 31.5 23.3 35.1 32.9 23.4 27.6 75.9 30.7 16.7 33.1 24.2 30.9 31.7 30.6 53.7 19.9 42.1 38.2 29.8 26.9 22.8 35.5 36.2 27.2 25.8 46.7 12.8 34.7 27.8 23.3 20.6 22.4 22.9 26.1 69.0 22.3 20.2 39.3 34.2 30.6 22.1 18.9 43.1 25.5 33.7 85.3 24.7 32.3 22.4 33.0 19.3 18.0 13.4 15.1 60.5 37.9 12.9 20.0 23.1 15.9 13.3 19.9 13.8 20.7 16.3 24.4 8.0 24.3 10.2 22.2 22.1 30.8 15.8 21.0 20.3 15.2 25.0 22.9 12.8 35.8 42.8 6.1 17.7 16.5 19.4 14.8 6.4 40.4 26.0 10.1 19.2 15.8 3.4 17.3 11.1 25.4 47.3 19.9 26.4 29.4 2.0 11.3 27.1 30.7 18.7 14.2 34.6 41.2 25.8 24.8 16.9 28.9 14.6 21.7 37.2 21.4 11.9 23.5 23.7 10.6 12.7 6.1 4.0 9.4 5.0 2.8 3.6 4.3 14.0 3.3 3.2 4.0 21.1 4.4 11.1 1.7 4.0 5.0 29.5 31.5 32.9 23.4 19.9 42.1 35.5 36.2 27.8 34.2 43.1 33.0 122.2 12.8 44.7 46.0 29.6 66.5 42.8 21.3 39.3 16.2 35.8 25.8 159.9 37.1 32.9 33.1 18.8 18.6 31.2 32.7 5.9 13.0 21.8 76.5 80.5 96.5 37.1 20.6 44.9 24.9 13.4 59.2 23.0 49.0 14.5 24.3 57.5 53.2 30.7 32.0 48.0 28.4 12.2 102.0 76.0 26.1 42.9 68.1 58.7 73.1 69.1 16.2 25.7 45.8 69.1 21.5 21.1 37.6 24.9 52.6 40.7 35.0 65.4 24.9 52.6 83.4 56.4 10.7 8.1 33.4 75.0 15.5 29.8 12.5 25.2 51.2 HLA-E ENSG00000204592 "Major histocompatibility complex, class I, E" P13747 6 30489509-30494194 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2347.3;Hepatic stellate cells: 1647.8;NK-cells: 1874.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 109.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 212.3;U-266/70: 284.8" "CAB024589, HPA031454" Enhanced Approved Vesicles "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB024589: AB_324025, HPA031454: AB_2673891" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (9.20e-2)" "unprognostic (2.47e-3)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (1.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (2.90e-1)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "unprognostic (1.42e-3)" 724.7 217.2 9.6 173.7 10.0 410.3 578.9 10.9 109.5 360.1 7.3 329.4 0.6 313.5 119.3 330.9 336.5 186.1 356.0 7.7 13.1 375.2 332.8 1144.6 336.3 16.6 22.7 213.2 156.6 95.8 121.8 117.3 16.1 251.2 116.8 12.4 252.5 93.0 179.2 518.3 428.9 89.0 10.0 1007.2 259.5 41.1 11.7 86.0 381.9 0.0 137.5 295.0 366.3 14.2 100.7 16.7 6.8 57.0 212.3 166.4 0.9 0.0 0.0 0.1 0.3 40.0 189.1 65.6 98.7 92.7 148.3 121.6 12.8 53.1 0.0 67.6 32.7 78.6 18.7 0.0 0.0 0.2 38.3 135.4 94.4 67.7 0.0 0.0 0.2 34.6 9.8 0.9 54.5 0.2 0.3 0.8 0.5 32.0 0.0 20.6 0.2 97.4 82.7 58.4 0.3 4.8 63.3 56.9 0.3 1.2 0.0 132.7 102.0 60.7 0.1 0.5 14.7 284.8 171.6 29.4 0.3 62.1 149.2 1140.0 335.4 1153.0 723.3 550.2 602.2 449.1 539.9 709.2 158.5 450.3 531.5 547.8 1916.1 512.9 648.0 138.3 611.7 1441.6 9.6 10.0 10.9 109.5 7.7 13.1 16.6 22.7 16.1 10.0 11.7 14.2 2347.3 310.9 411.0 8.1 950.6 484.6 386.6 284.2 183.8 2.7 238.7 204.0 108.3 231.6 270.0 123.2 6.2 88.2 1304.6 603.0 17.6 484.9 5.0 157.7 157.9 1554.7 216.2 172.3 0.1 677.2 277.0 402.8 233.4 325.6 531.6 59.2 1647.8 120.1 700.6 5.0 0.1 545.3 248.2 1220.4 512.2 11.0 132.0 821.6 466.0 105.9 740.5 100.2 1874.4 2.0 0.5 682.2 559.1 76.3 716.6 436.9 473.9 79.9 214.7 9.5 177.5 535.1 350.1 10.6 7.0 170.0 426.5 359.0 1162.1 196.5 285.0 544.4 HOXC8 "HOX3, HOX3A" ENSG00000037965 "Homeobox C8" P31273 12 54008985-54012769 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 15.4;skeletal muscle: 16.8" "Cell type enhanced" "Detected in some" "Fibroblasts: 12.2;Granulosa cells: 11.0;Melanocytes: 10.6;Peritubular cells: 7.9;Proximal tubular cells: 7.4;Skeletal myocytes: 17.9;Smooth muscle cells: 7.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 41.6;ASC TERT1: 27.6;fHDF/TERT166: 49.8;HSkMC: 33.2;LHCN-M2: 38.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "spinal cord: 10.5" "HPA028911, CAB037020" Uncertain Supported Nucleoplasm,Microtubules NA NA "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm Microtubules "CAB037020: AB_1840935, HPA028911: AB_10602236" "unprognostic (1.03e-1)" "unprognostic (5.90e-2)" "unprognostic (6.26e-6)" "unprognostic (4.89e-2)" "unprognostic (5.20e-4)" "unprognostic (5.34e-3)" "unprognostic (2.43e-3)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" "unprognostic (1.45e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.47e-5)" "unprognostic (2.47e-1)" "unprognostic (1.84e-2)" "unprognostic (4.68e-2)" "unprognostic (1.14e-2)" 5.2 5.2 0.0 0.7 0.0 0.0 5.6 0.0 0.0 0.4 0.0 0.4 0.0 0.4 15.4 0.2 7.9 0.0 0.0 0.0 0.0 4.9 0.0 0.1 1.8 0.1 0.0 4.5 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.3 0.0 0.1 16.8 3.1 5.7 7.6 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 1.0 2.7 0.0 15.0 41.6 27.6 0.2 2.8 0.1 4.9 3.1 4.4 2.4 0.0 0.3 49.8 0.8 2.0 3.9 1.2 5.4 5.3 5.3 0.9 2.1 0.0 4.9 0.0 5.8 33.2 3.9 15.7 9.0 0.5 0.4 0.8 0.6 0.0 38.7 1.2 0.0 0.4 0.0 0.3 0.7 0.0 0.0 0.0 6.1 0.0 0.0 2.0 5.4 1.0 13.8 3.6 1.6 0.0 0.0 1.0 8.0 6.8 1.7 0.1 0.0 0.0 0.9 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 4.6 0.1 0.0 1.2 0.0 1.5 2.9 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.2 1.9 0.0 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 12.2 0.0 0.0 0.0 11.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.2 6.2 0.2 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.1 0.3 7.4 0.0 1.3 6.6 17.9 7.6 5.6 3.1 0.2 4.3 0.3 0.3 3.2 0.1 0.1 HSD11B1 "HSD11, HSD11B, SDR26C1" ENSG00000117594 "Hydroxysteroid 11-beta dehydrogenase 1" P28845 1 209686178-209734949 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 968.3" "Cell type enriched" "Detected in many" 9 "Hepatocytes: 646.2" "Cancer enriched" "Detected in all" 28 "liver cancer: 197.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 5.6" "Lineage enriched" "Detected in single" 17 "T-cells: 5.6" "Cell line enriched" "Detected in some" 5 "ASC diff: 989.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047729 Enhanced NA NA 110000 "Cluster 35: T-regs - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA047729: AB_2680135" "unprognostic (1.08e-3)" "unprognostic (2.13e-1)" "unprognostic (2.32e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "unprognostic (3.68e-1)" "unprognostic (2.02e-2)" "unprognostic (1.12e-1)" "unprognostic (1.30e-1)" "unprognostic (3.63e-2)" "unprognostic (8.35e-3)" "unprognostic (8.69e-2)" "prognostic unfavorable (1.97e-10)" "unprognostic (3.41e-2)" "unprognostic (3.91e-2)" "unprognostic (6.45e-2)" "unprognostic (1.59e-2)" 22.4 7.7 9.8 14.6 15.4 0.3 12.0 23.0 22.0 2.8 8.1 4.2 1.2 4.2 15.7 2.1 5.1 8.0 7.5 11.0 16.0 24.3 968.3 39.9 4.3 14.3 21.4 59.9 3.2 0.2 8.8 72.5 16.3 27.8 3.3 0.6 2.5 13.0 5.5 33.8 5.0 12.9 9.4 7.3 7.1 7.2 12.8 0.6 5.2 10.6 1.9 27.9 6.3 17.5 0.4 0.0 0.0 0.0 989.2 102.8 0.0 0.1 36.0 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.1 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 206.6 0.2 0.1 5.4 0.0 6.9 0.4 0.9 0.0 0.0 0.0 51.2 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.7 16.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 34.9 8.4 4.0 0.2 0.2 0.3 1.4 0.3 0.3 5.7 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 5.6 1.2 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 1.7 0.4 9.8 15.4 23.0 22.0 11.0 16.0 14.3 21.4 16.3 9.4 12.8 17.5 0.4 3.2 0.0 1.3 0.8 0.1 0.4 4.8 0.6 0.5 0.2 0.0 1.4 30.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.2 0.9 0.6 1.0 0.0 5.3 3.3 0.0 0.1 66.4 0.5 2.8 0.0 0.0 7.5 646.2 8.3 0.0 2.8 0.0 0.0 7.9 2.3 2.8 29.2 3.7 0.0 28.1 0.6 16.2 0.0 0.5 55.7 0.4 0.0 7.9 0.0 0.9 0.0 0.2 0.1 0.5 0.0 2.6 5.5 0.0 0.2 0.1 0.1 0.3 1.1 0.3 0.0 1.7 HSD17B12 "KAR, SDR12C1" ENSG00000149084 "Hydroxysteroid 17-beta dehydrogenase 12" Q53GQ0 11 43680680-43856617 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016427 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "HPA016427: AB_1844347" "unprognostic (1.93e-1)" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-3)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.99e-1)" "unprognostic (3.31e-2)" "unprognostic (9.16e-3)" "unprognostic (5.16e-2)" "unprognostic (7.54e-2)" "prognostic favorable (2.10e-8)" "unprognostic (6.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.43e-1)" "unprognostic (2.28e-2)" 60.9 65.4 42.0 31.4 50.4 25.1 48.8 58.1 63.0 51.3 71.5 65.8 67.3 37.4 50.6 36.3 41.3 35.6 69.5 42.0 54.3 91.3 122.9 51.4 28.5 58.8 52.1 45.3 43.5 134.3 28.5 41.6 58.9 52.8 59.5 47.0 46.9 41.5 27.8 30.0 41.7 48.6 52.8 34.8 56.1 33.5 48.9 22.3 66.8 51.6 32.3 31.4 26.8 61.9 40.2 64.3 68.4 69.6 226.8 211.5 45.0 96.7 97.8 67.3 73.0 75.7 80.7 97.4 69.4 91.5 111.7 151.6 48.7 125.5 82.6 19.0 89.2 46.4 28.3 66.2 114.6 132.3 125.4 131.1 93.6 68.1 193.6 85.9 96.1 60.4 43.9 157.9 59.4 22.9 38.6 63.1 126.0 49.9 45.3 63.9 102.3 110.8 129.5 95.9 24.5 56.5 132.0 110.7 100.2 64.6 80.2 112.5 92.4 73.9 28.3 189.3 117.6 81.6 110.3 58.3 78.5 25.0 55.4 8.8 13.4 7.0 12.1 14.8 13.5 12.7 9.6 10.5 21.3 15.2 15.6 13.9 11.2 16.4 8.2 18.4 6.2 11.6 42.0 50.4 58.1 63.0 42.0 54.3 58.8 52.1 58.9 52.8 48.9 61.9 73.6 64.1 111.1 96.6 45.4 31.7 47.1 92.8 57.5 77.1 46.1 36.4 80.7 74.4 81.4 51.5 77.2 60.4 30.6 82.2 27.4 100.2 61.8 36.9 47.5 70.9 138.2 40.8 126.9 82.3 42.1 59.7 60.6 37.0 155.9 37.3 76.1 214.0 63.5 121.1 155.6 75.5 87.5 50.9 43.7 24.1 34.2 45.3 39.2 59.0 37.2 128.2 30.9 128.7 97.5 71.4 62.5 56.8 61.4 61.3 54.2 50.1 75.8 67.8 78.9 45.4 60.2 17.5 14.5 66.0 45.7 74.8 29.4 95.5 115.5 48.6 HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452473-119637199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 320.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.1;Oligodendrocytes: 221.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 75.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 450000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favorable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" 74.4 85.0 37.2 41.9 50.2 19.7 44.4 51.1 50.0 68.8 47.2 64.5 79.3 34.1 53.0 50.9 39.1 52.5 68.6 34.9 50.7 84.4 320.0 75.6 33.2 50.6 49.5 34.8 55.2 75.5 26.5 53.4 49.2 56.8 65.9 27.2 44.9 79.0 59.8 51.8 87.6 39.5 44.7 36.6 53.8 20.9 49.9 31.9 133.9 52.8 39.7 57.7 31.5 56.3 68.8 59.8 104.1 143.7 261.8 120.3 57.9 63.4 80.3 57.3 103.0 49.4 112.8 84.4 128.0 70.6 81.0 68.7 77.0 144.4 84.3 94.6 79.8 118.1 62.0 96.9 65.8 38.0 169.9 110.0 56.3 64.9 54.7 69.3 103.9 59.4 41.0 48.9 64.2 64.0 59.2 23.6 82.1 161.1 43.1 68.7 103.0 104.8 92.2 192.7 81.1 70.6 149.0 23.4 78.7 93.3 88.7 68.2 67.6 52.7 38.1 66.5 53.1 26.3 55.3 32.6 63.7 104.4 56.7 75.5 27.3 49.9 6.5 15.5 7.3 11.1 5.8 5.3 21.3 10.3 5.5 5.2 4.9 6.9 17.1 13.8 4.1 12.2 37.2 50.2 51.1 50.0 34.9 50.7 50.6 49.5 49.2 44.7 49.9 56.3 38.9 73.7 125.2 47.3 28.2 14.9 42.5 43.2 24.5 19.7 31.1 22.1 76.4 64.3 52.3 36.8 14.6 64.3 19.1 40.0 84.1 39.9 8.8 29.0 48.9 32.3 33.0 42.1 92.9 35.8 29.3 35.6 48.4 35.8 68.4 25.3 32.2 225.1 77.9 15.2 102.8 45.8 22.4 51.8 13.8 13.4 34.5 46.7 8.8 49.6 85.7 47.3 9.2 78.4 221.5 20.5 29.6 51.1 23.1 24.8 85.7 65.4 33.8 18.6 6.6 29.2 32.2 30.6 22.7 34.7 17.2 65.0 15.7 57.2 55.3 39.7 HSPB2 "Hs.78846, MKBP" ENSG00000170276 "Heat shock protein family B (small) member 2" Q16082 11 111912734-111914093 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 153.2;skeletal muscle: 251.3;tongue: 316.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.7;Fibroblasts: 39.1;Leydig cells: 43.5;Melanocytes: 37.4;Smooth muscle cells: 39.8" "Cancer enhanced" "Detected in many" "melanoma: 5.1;renal cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 48.4;ASC TERT1: 23.4;fHDF/TERT166: 59.7;HSkMC: 23.3;LHCN-M2: 35.2;U-138 MG: 31.5" HPA079414 Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA079414: " "unprognostic (5.46e-2)" "unprognostic (1.46e-1)" "unprognostic (2.30e-1)" "unprognostic (7.69e-3)" "unprognostic (6.82e-2)" "unprognostic (1.51e-2)" "unprognostic (4.37e-2)" "unprognostic (3.25e-1)" "unprognostic (2.04e-1)" "unprognostic (1.67e-2)" "unprognostic (3.55e-2)" "unprognostic (2.19e-1)" "unprognostic (1.36e-1)" "unprognostic (1.69e-3)" "unprognostic (2.63e-1)" "unprognostic (1.99e-1)" "unprognostic (1.46e-2)" 39.8 5.3 26.7 4.3 28.9 0.0 21.5 37.4 32.5 30.2 24.4 21.1 3.4 25.0 5.7 15.4 22.2 18.5 153.2 25.8 26.7 13.3 2.3 17.3 5.4 29.0 27.3 14.0 1.4 1.4 3.8 12.2 27.2 13.1 4.0 1.8 7.1 13.0 251.3 14.7 9.1 19.1 27.2 7.3 9.6 2.3 28.9 1.4 9.6 316.8 2.0 16.1 19.0 26.2 0.0 0.0 0.0 7.0 48.4 23.4 0.2 5.6 0.0 0.0 0.3 0.0 0.0 0.0 0.5 59.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 23.3 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 35.2 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.2 31.5 3.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.7 28.9 37.4 32.5 25.8 26.7 29.0 27.3 27.2 27.2 28.9 26.2 8.5 0.0 0.0 0.0 0.0 7.0 0.3 0.0 1.2 0.4 5.1 16.4 115.7 1.5 0.6 1.8 0.0 0.8 0.1 0.0 1.9 0.4 0.1 0.1 7.9 3.5 0.0 0.0 0.0 0.0 0.7 39.1 0.0 0.2 0.0 0.4 4.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 10.3 1.1 43.5 0.6 37.4 0.0 0.0 7.6 0.0 0.0 0.0 0.1 0.0 21.8 0.0 0.3 0.0 23.5 0.0 0.5 13.1 22.8 39.8 0.8 0.6 0.6 5.8 1.5 1.0 0.4 0.0 0.0 HSPB6 "FLJ32389, Hsp20, PPP1R91" ENSG00000004776 "Heat shock protein family B (small) member 6" O14558 19 35754566-35758079 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 2969.8;tongue: 1759.1" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 165.7;Fibroblasts: 125.2;Leydig cells: 271.8;Peritubular cells: 220.4;Smooth muscle cells: 102.6;Theca cells: 311.0" "Cancer enhanced" "Detected in all" "stomach cancer: 93.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1774.3;ASC TERT1: 742.0;HHSteC: 599.9;HSkMC: 700.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001974, HPA044153, HPA054811" Enhanced Supported "Nucleoli,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 310000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Nucleoli, Golgi apparatus" "CAB001974: , HPA044153: AB_2678836, HPA054811: AB_2682610" "unprognostic (3.19e-2)" "unprognostic (8.07e-2)" "unprognostic (1.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.21e-3)" "unprognostic (7.02e-2)" "unprognostic (9.67e-2)" "unprognostic (7.57e-2)" "unprognostic (1.18e-1)" "unprognostic (7.23e-2)" "unprognostic (1.20e-1)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.32e-2)" "unprognostic (6.65e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.43e-6)" 650.0 414.0 37.3 45.4 40.6 0.4 394.9 32.5 49.2 581.9 26.1 699.9 28.1 565.1 101.6 112.3 495.1 97.9 1463.9 30.0 43.6 69.0 42.3 126.6 5.7 76.7 48.5 455.2 50.5 4.2 17.5 40.2 73.7 271.2 44.0 21.1 115.9 194.7 2969.8 39.1 180.0 278.2 50.8 15.7 362.1 60.6 53.8 6.2 99.5 1759.1 2.7 537.3 290.6 49.3 0.6 0.7 2.1 2.5 1774.3 742.0 1.2 83.0 1.3 4.9 9.3 1.1 0.4 0.7 0.6 252.4 0.0 0.2 0.4 0.7 3.9 0.9 0.5 0.4 1.3 0.5 599.9 0.2 0.9 700.3 0.0 19.1 0.9 2.2 5.4 0.3 0.5 1.0 0.2 0.3 0.4 1.9 1.2 2.3 0.6 1.5 0.5 0.7 0.0 0.1 0.8 0.7 0.1 0.2 0.7 0.3 0.3 0.5 0.1 153.2 0.9 17.3 0.6 1.0 2.8 0.3 20.5 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.3 40.6 32.5 49.2 30.0 43.6 76.7 48.5 73.7 50.8 53.8 49.3 11.1 3.2 0.6 1.6 0.1 1.8 0.4 0.0 3.4 7.8 0.5 0.5 29.7 0.0 0.0 0.0 0.0 2.5 0.1 0.1 0.0 0.1 27.0 4.9 165.7 3.6 0.0 5.2 0.2 0.0 2.5 125.2 4.1 3.5 0.0 3.6 17.5 0.3 5.0 0.0 0.5 0.0 0.0 0.3 3.6 18.9 271.8 2.7 1.8 0.0 0.6 44.5 0.0 0.0 0.1 0.2 0.0 220.4 0.1 0.4 0.0 0.4 0.0 2.8 26.3 38.0 102.6 2.3 1.4 1.9 2.0 4.8 1.8 311.0 0.0 0.5 HTR2A "5-HT2A, HTR2" ENSG00000102468 "5-hydroxytryptamine receptor 2A" P28223 13 46831546-46897076 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Behavior, Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.2;choroid plexus: 5.6" "Cell type enriched" "Detected in some" 8 "Excitatory neurons: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.8;ASC TERT1: 4.6;BEWO: 1.4;HEL: 1.5;U-138 MG: 2.3;U-2 OS: 1.4;U-87 MG: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014011 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA014011: AB_1856709" "unprognostic (8.01e-2)" "unprognostic (2.71e-2)" "unprognostic (9.49e-2)" "unprognostic (7.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.99e-1)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (5.27e-2)" "unprognostic (3.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.90e-1)" "unprognostic (9.94e-5)" "unprognostic (4.78e-3)" "unprognostic (2.54e-1)" "unprognostic (2.91e-2)" "unprognostic (8.28e-2)" 0.9 0.3 6.7 0.8 9.7 0.1 0.5 0.0 15.2 0.6 5.6 0.5 0.4 0.5 0.0 0.5 0.3 1.6 0.7 11.8 8.7 0.1 0.1 0.3 0.0 0.5 1.4 0.3 0.0 0.0 0.2 0.0 2.9 0.2 0.6 0.8 0.0 0.6 0.3 0.1 0.4 2.6 0.1 0.0 0.2 0.6 1.6 0.7 0.1 0.6 0.2 0.8 0.5 5.8 0.0 0.0 0.0 0.0 1.8 4.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.3 1.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 6.7 9.7 0.0 15.2 11.8 8.7 0.5 1.4 2.9 0.1 1.6 5.8 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.5 0.2 1.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.2 8.6 0.1 0.0 0.0 81.7 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.4 0.1 0.1 0.0 10.1 0.0 0.0 0.3 0.0 2.2 0.9 1.9 0.0 3.7 0.0 4.6 0.0 2.5 3.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.0 1.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 ICMT "HSTE14, PCCMT, PPMT" ENSG00000116237 "Isoprenylcysteine carboxyl methyltransferase" O60725 1 6221193-6235972 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 85.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 112.8" "Low region specificity" "Detected in all" "HPA032024, HPA032025" Uncertain NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA032024: AB_2674115, HPA032025: AB_10601819" "unprognostic (1.95e-3)" "unprognostic (3.83e-2)" "unprognostic (7.34e-2)" "unprognostic (4.40e-2)" "unprognostic (5.53e-2)" "unprognostic (9.30e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (2.30e-2)" "unprognostic (7.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.87e-1)" "unprognostic (6.58e-2)" "unprognostic (2.11e-2)" "unprognostic (4.11e-1)" "unprognostic (5.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.99e-3)" 22.6 23.0 12.4 13.6 18.1 4.0 15.8 18.2 13.1 20.3 17.7 20.9 19.6 20.1 20.9 21.6 16.2 13.1 27.1 12.5 12.9 25.9 13.6 14.9 10.2 12.6 14.9 9.1 17.4 26.8 22.0 21.0 12.7 17.3 17.4 28.7 17.1 18.9 53.0 19.2 18.3 21.9 12.3 9.1 15.7 5.2 14.5 14.9 18.1 82.6 11.0 17.4 16.0 12.0 35.8 32.6 43.7 43.0 131.2 51.8 18.7 84.9 56.1 48.7 36.9 35.0 28.2 39.0 31.7 66.7 42.0 47.4 50.5 35.6 51.5 78.8 51.3 26.8 46.0 26.8 25.5 42.5 36.4 33.3 23.5 51.2 19.2 32.4 38.5 31.6 26.5 29.8 55.7 22.3 43.2 29.6 29.7 64.1 46.0 35.8 61.5 22.6 59.3 25.8 59.2 28.8 41.3 96.3 37.2 48.4 25.2 35.4 48.1 55.3 21.7 65.4 61.6 27.7 57.8 30.5 27.1 96.5 29.3 2.6 1.9 1.6 3.1 2.2 2.7 1.1 2.5 3.1 1.7 1.8 2.1 1.8 0.6 1.8 1.9 2.7 1.4 1.9 12.4 18.1 18.2 13.1 12.5 12.9 12.6 14.9 12.7 12.3 14.5 12.0 18.0 22.4 12.1 5.9 7.7 6.2 9.6 12.2 7.4 18.0 16.3 9.8 39.3 15.7 19.6 29.5 31.3 57.6 12.3 40.7 13.7 21.9 3.5 19.5 18.8 18.1 22.8 14.9 10.2 22.2 85.7 19.6 12.8 16.9 5.1 13.9 21.8 23.9 29.1 48.8 9.4 21.4 12.2 12.0 7.0 5.1 20.8 9.8 7.2 7.5 12.1 18.9 10.3 2.0 5.4 26.8 12.2 26.4 18.3 14.1 45.5 36.9 41.7 58.8 13.1 9.9 22.1 15.4 26.8 28.2 10.4 32.0 10.4 13.9 23.1 14.7 IFITM2 "1-8D, DSPA2c" ENSG00000185201 "Interferon induced transmembrane protein 2" Q01629 11 303655-309397 "Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 920.0;NK-cells: 1350.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 23410.9" "Lineage enriched" "Detected in all" 11 "granulocytes: 23410.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 424.6;HHSteC: 547.7;HMC-1: 494.9;HSkMC: 710.9;NB-4: 603.3;U-937: 485.2" "HPA004337, HPA044731" Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA 450000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "Cell Junctions" Nucleoplasm "HPA004337: AB_1851427, HPA044731: " "unprognostic (2.39e-2)" "unprognostic (2.69e-2)" "unprognostic (4.54e-1)" "unprognostic (1.65e-2)" "unprognostic (3.41e-2)" "unprognostic (1.86e-1)" "unprognostic (3.56e-2)" "unprognostic (3.87e-2)" "unprognostic (3.87e-1)" "unprognostic (2.36e-1)" "unprognostic (2.46e-3)" "unprognostic (1.64e-2)" "prognostic unfavorable (2.37e-9)" "unprognostic (2.79e-1)" "unprognostic (3.28e-2)" "unprognostic (1.51e-1)" "unprognostic (1.16e-2)" 1086.2 307.0 90.3 258.0 90.2 177.0 681.0 89.6 116.6 785.6 101.4 358.6 40.9 702.8 52.1 237.2 903.8 97.4 619.6 92.0 97.9 703.1 1288.5 1069.9 99.9 94.4 89.4 650.1 211.1 112.0 200.6 145.3 94.9 406.1 41.8 27.0 228.9 102.5 195.9 236.7 305.6 200.4 92.8 1402.1 304.3 123.0 95.4 29.8 437.7 132.8 105.8 493.1 496.6 95.1 32.2 65.4 313.1 2.9 137.2 358.3 0.9 106.8 65.1 27.0 63.3 1.7 206.9 2.7 126.6 424.6 0.4 68.5 1.1 9.3 9.0 1.8 41.1 75.1 102.6 117.6 547.7 124.1 494.9 710.9 2.3 5.2 3.3 64.4 51.2 22.5 5.2 210.5 11.6 129.9 2.5 603.3 36.4 5.3 229.4 101.0 29.9 1.1 181.6 0.4 0.8 7.0 65.4 74.9 34.5 5.3 86.7 69.8 338.3 5.7 26.8 36.1 1.4 4.5 5.0 3.3 14.5 485.2 18.1 2706.4 537.4 3789.5 666.6 1421.9 480.8 846.9 590.1 639.5 612.5 799.2 511.7 510.3 23410.9 1225.0 2199.0 279.0 411.7 1376.6 90.3 90.2 89.6 116.6 92.0 97.9 94.4 89.4 94.9 92.8 95.4 95.1 920.0 307.7 540.0 5.9 301.1 104.4 251.1 161.4 215.1 0.3 59.7 66.5 51.8 154.4 209.2 248.3 0.0 8.3 814.7 22.5 487.2 433.0 7.8 67.1 468.6 828.4 9.6 100.7 0.0 256.7 16.9 515.8 30.5 78.5 530.5 68.8 752.1 684.1 223.4 0.0 0.0 39.4 24.4 372.8 255.9 31.5 507.6 645.9 209.9 12.2 177.3 80.5 1350.1 0.0 0.1 161.9 149.2 223.8 123.0 126.3 4.7 45.3 104.8 1.5 315.5 442.5 568.4 8.4 10.4 22.8 83.0 23.4 667.2 61.8 44.3 102.4 IFT122 "FAP80, SPG, WDR10, WDR10p, WDR140" ENSG00000163913 "Intraflagellar transport 122" Q9HBG6 3 129440036-129520507 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 72.8" "Cell type enhanced" "Detected in many" "Early spermatids: 81.7;Late spermatids: 70.3;Spermatocytes: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041815 Uncertain Uncertain Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA041815: AB_10804118" "unprognostic (7.16e-2)" "unprognostic (3.71e-3)" "unprognostic (3.67e-1)" "unprognostic (7.61e-3)" "unprognostic (5.29e-2)" "unprognostic (5.33e-3)" "unprognostic (4.68e-2)" "unprognostic (1.82e-1)" "unprognostic (7.90e-2)" "unprognostic (3.30e-1)" "unprognostic (1.67e-2)" "unprognostic (3.50e-2)" "unprognostic (1.09e-2)" "unprognostic (7.67e-2)" "unprognostic (5.33e-1)" "unprognostic (9.91e-2)" "unprognostic (4.20e-3)" 9.6 7.4 5.7 5.2 7.6 10.1 12.4 6.5 9.2 13.1 15.3 7.6 4.7 12.6 12.7 7.2 24.7 6.7 12.0 6.8 6.8 11.7 9.2 8.8 6.7 4.5 6.2 25.4 13.3 13.9 14.4 10.8 3.0 7.4 6.9 11.2 7.9 8.5 3.9 13.8 5.3 8.9 3.7 4.5 9.0 72.8 7.0 8.9 13.1 2.9 5.7 6.6 8.4 6.3 16.5 24.6 21.0 13.5 29.7 21.0 10.5 8.5 12.9 14.8 14.1 11.9 10.7 10.6 10.0 11.3 14.5 10.4 8.2 7.7 13.3 5.8 8.8 8.2 21.8 10.3 8.1 22.2 7.2 24.7 5.7 11.4 8.8 12.9 20.3 21.8 8.4 22.1 12.1 18.2 18.2 11.6 14.1 12.3 7.0 16.3 8.0 7.7 15.7 3.0 25.9 10.6 24.8 8.2 7.5 7.9 22.6 17.9 9.0 10.1 8.7 13.6 10.2 15.0 11.4 9.3 9.2 11.3 8.1 4.5 3.1 3.7 0.9 2.2 1.6 1.9 1.6 2.3 3.2 2.1 1.8 2.2 1.4 1.5 0.9 0.8 3.0 2.1 5.7 7.6 6.5 9.2 6.8 6.8 4.5 6.2 3.0 3.7 7.0 6.3 7.5 9.6 8.2 28.1 4.3 2.7 5.8 4.5 2.8 9.7 18.0 13.3 6.4 15.7 5.6 25.8 37.5 6.7 4.5 6.2 7.9 5.2 81.7 43.4 11.0 9.7 3.0 7.4 35.1 8.9 5.2 9.8 19.9 10.2 5.1 8.7 20.7 6.0 9.3 5.0 23.1 10.2 4.1 7.2 2.2 70.3 18.6 4.1 3.6 15.0 3.8 11.8 3.1 12.1 15.9 3.4 4.2 13.9 3.4 3.6 6.2 8.2 37.3 21.4 0.0 12.8 7.7 120.4 38.0 5.4 2.8 2.6 4.1 10.6 8.7 3.4 IGBP1 "α4, IBP1" ENSG00000089289 "Immunoglobulin binding protein 1" P78318 X 70133447-70166324 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" Chaperone "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 342.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000634, HPA001004, CAB034139" Approved Approved Cytosol NA NA 48000 "Cluster 44: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 32: Non-specific - Translation" Cytosol "CAB034139: AB_2295670, HPA000634: AB_1079102, HPA001004: AB_1079104" "unprognostic (3.59e-2)" "unprognostic (5.35e-2)" "unprognostic (2.05e-1)" "unprognostic (5.35e-3)" "unprognostic (1.22e-2)" "unprognostic (1.11e-2)" "unprognostic (4.84e-3)" "unprognostic (2.21e-2)" "unprognostic (1.50e-1)" "unprognostic (2.22e-1)" "unprognostic (1.74e-1)" "unprognostic (3.00e-1)" "unprognostic (2.67e-2)" "unprognostic (1.46e-1)" "unprognostic (5.86e-2)" "unprognostic (1.42e-2)" "unprognostic (4.10e-3)" 56.3 43.2 38.5 29.7 40.3 57.5 55.1 40.3 45.8 68.6 36.9 60.2 57.8 53.3 62.0 46.6 73.5 48.3 53.4 38.6 40.4 57.9 29.4 36.6 59.4 40.4 39.9 119.1 118.6 38.7 35.6 37.6 40.6 42.2 56.2 30.1 64.4 32.1 118.0 63.4 58.3 42.4 41.7 40.7 70.1 18.7 39.7 68.2 57.3 99.9 69.5 52.4 54.5 42.7 42.7 48.9 30.9 35.9 122.2 163.3 44.5 35.6 99.6 47.9 57.1 45.5 55.7 79.1 58.7 62.0 62.6 57.1 73.8 59.1 60.8 31.4 53.2 25.1 52.7 82.9 83.6 59.4 43.9 158.1 143.1 44.3 63.2 166.6 81.8 57.9 51.4 69.5 52.6 42.7 48.7 100.4 37.5 98.0 73.6 42.3 65.0 79.5 77.8 67.2 35.4 43.4 46.3 40.0 87.0 56.4 21.3 61.1 65.8 25.8 40.2 46.0 27.2 65.0 53.7 40.1 36.4 50.5 31.1 51.4 46.1 41.8 34.1 46.0 40.9 50.9 47.4 45.2 51.1 41.8 53.7 48.9 31.4 39.8 39.0 25.6 75.2 48.0 38.5 40.3 40.3 45.8 38.6 40.4 40.4 39.9 40.6 41.7 39.7 42.7 50.1 32.1 54.7 12.1 79.3 100.1 114.2 163.9 82.0 21.5 81.4 82.2 75.8 70.1 85.6 27.6 8.4 123.8 45.3 91.3 103.7 80.3 126.3 58.0 61.1 64.1 69.9 38.9 19.3 143.2 129.0 62.2 46.9 57.9 34.8 90.8 85.3 20.9 82.7 6.7 19.5 128.0 69.2 123.1 89.6 121.5 81.4 75.6 49.8 15.0 119.8 48.9 90.6 13.6 27.6 86.4 153.1 61.7 52.9 70.8 342.0 182.0 57.8 23.6 26.3 62.3 63.0 12.2 25.0 76.2 120.3 124.9 81.9 96.1 128.4 130.4 IGFBP4 "BP-4, HT29-IGFBP, IBP4, IGFBP-4" ENSG00000141753 "Insulin like growth factor binding protein 4" P22692 17 40443450-40457725 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 672.7;Endometrial stromal cells: 542.2;Endothelial cells: 502.3;Fibroblasts: 585.4;Hepatic stellate cells: 566.5;Hepatocytes: 501.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 19.5;NK-cell: 37.0" "Group enriched" "Detected in many" 5 "NK-cells: 37.0;T-cells: 19.5" "Cell line enhanced" "Detected in many" "A549: 1334.8;ASC diff: 961.5;ASC TERT1: 933.8;BJ: 1066.4;BJ hTERT+: 1088.2;HSkMC: 2001.2;U-2197: 882.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066240 Supported "Secreted to blood" NA NA 227000000 410000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA066240: AB_2685643" "unprognostic (1.03e-3)" "unprognostic (1.61e-1)" "unprognostic (1.85e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.44e-3)" "unprognostic (1.00e-1)" "prognostic favorable (5.49e-4)" "unprognostic (4.55e-2)" "unprognostic (1.19e-2)" "unprognostic (2.28e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (2.72e-5)" "unprognostic (6.23e-2)" "unprognostic (1.73e-1)" "unprognostic (2.36e-1)" "unprognostic (3.81e-2)" 884.7 248.1 26.0 307.7 26.9 2.4 754.6 25.3 46.5 1020.7 65.0 618.0 82.8 795.8 141.9 246.7 791.1 391.4 502.9 25.6 28.2 464.4 1475.9 390.1 60.0 29.5 34.1 1270.4 164.4 44.6 203.7 231.8 28.9 470.0 133.5 13.1 264.4 279.0 107.3 241.7 289.5 645.1 28.3 295.5 369.6 67.7 35.3 38.9 501.4 97.4 44.2 552.1 576.2 25.8 0.2 1334.8 66.8 0.5 961.5 933.8 2.2 1066.4 1088.2 199.7 154.4 59.7 17.3 0.3 563.7 511.0 27.2 11.9 22.6 6.8 90.2 4.8 1.3 4.3 91.3 89.9 601.2 2.9 0.5 2001.2 4.6 267.7 37.7 23.8 350.6 0.1 21.7 0.2 290.5 41.2 0.8 252.5 37.2 58.9 178.2 67.2 1.3 2.1 8.4 42.1 18.3 53.0 482.3 2.0 17.0 63.5 486.6 24.7 534.7 276.0 14.4 882.1 1.1 0.9 0.6 1.7 163.8 9.9 72.4 0.0 0.0 0.0 2.7 0.0 19.5 0.8 5.0 6.7 0.0 5.2 0.3 0.6 0.0 37.0 0.0 0.2 0.0 1.4 26.0 26.9 25.3 46.5 25.6 28.2 29.5 34.1 28.9 28.3 35.3 25.8 672.7 9.6 37.4 1.3 17.6 56.3 97.1 36.7 79.1 3.2 118.9 163.2 16.9 90.1 16.2 7.3 0.0 6.1 10.6 93.3 17.6 4.1 6.7 69.8 542.2 502.3 8.4 37.9 3.8 2.4 7.2 585.4 13.7 59.1 2.5 230.9 566.5 501.2 273.6 1.7 3.4 74.7 4.1 42.8 94.0 16.5 246.4 21.3 72.9 18.7 3.4 3.8 1.0 1.0 0.3 39.1 72.1 118.5 7.4 63.8 71.6 204.7 18.5 1.1 190.7 13.8 299.9 1.9 8.2 26.8 47.7 7.5 20.3 25.9 109.0 73.6 IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 580.8;Fibroblasts: 1360.5;Leydig cells: 1030.8;Peritubular cells: 1495.9;Sertoli cells: 1170.1;Smooth muscle cells: 420.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 145.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.6;non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 1163.6;BJ: 476.9;BJ hTERT+: 683.3;fHDF/TERT166: 1045.9;hTERT-RPE1: 468.5;U-87 MG: 631.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 120.2" "HPA008005, HPA075088" Uncertain "Secreted to blood" NA NA 199000000 300000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA008005: AB_1851499, HPA075088: " "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" 145.8 90.2 28.1 9.2 32.6 0.4 150.5 31.8 40.8 276.6 71.6 75.5 20.8 117.2 129.5 75.8 237.4 36.8 107.0 28.4 33.1 30.6 7.7 40.4 8.7 32.7 29.2 136.8 15.9 4.8 106.3 15.7 33.2 129.3 28.0 6.6 35.9 122.2 38.5 39.2 52.5 39.0 36.7 45.2 67.6 22.2 41.7 6.8 58.4 102.2 9.2 127.1 214.1 27.2 135.3 219.6 0.2 177.3 313.9 1163.6 0.8 476.9 683.3 126.9 69.0 23.2 294.7 0.0 68.5 1045.9 96.4 453.3 3.0 42.3 26.2 1.2 2.8 4.4 37.1 33.3 111.9 0.8 1.1 325.5 2.3 57.4 11.9 468.5 30.5 7.5 0.6 9.3 53.1 0.5 6.6 1.0 6.8 4.1 150.4 2.3 4.9 5.6 10.1 3.3 1.3 8.7 152.2 0.0 10.9 4.0 6.3 0.5 132.2 87.2 41.2 95.5 18.0 5.3 10.7 0.6 631.6 6.7 49.5 0.0 0.0 31.6 0.6 6.8 3.4 0.1 1.0 5.4 2.1 0.0 0.5 6.8 0.0 0.0 20.1 0.0 0.0 1.5 28.1 32.6 31.8 40.8 28.4 33.1 32.7 29.2 33.2 36.7 41.7 27.2 83.9 6.4 4.2 2.0 3.4 113.6 41.0 580.8 23.9 2.5 5.9 29.0 21.1 10.0 37.6 20.2 0.0 3.0 3.5 0.2 11.7 87.9 9.6 4.9 99.2 71.9 0.0 3.2 3.1 8.0 4.9 1360.5 30.5 2.5 0.0 2.3 116.4 0.8 7.6 0.0 3.6 0.3 50.8 6.8 122.8 32.6 1030.8 15.2 144.1 19.7 2.5 51.1 0.0 1.5 0.9 77.1 0.0 1495.9 9.6 94.9 0.0 15.2 13.9 2.8 1170.1 102.3 420.9 3.8 6.8 8.0 87.8 3.4 14.1 0.4 0.0 34.1 IGIP "C5orf53, LOC492311" ENSG00000182700 "IgA inducing protein" A6NJ69 5 140125937-140129392 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 55.4" "Cell type enhanced" "Detected in many" "Horizontal cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.7;ASC TERT1: 13.1" "Low region specificity" "Detected in all" "HPA041877, HPA048615" Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA041877: AB_2677721, HPA048615: AB_2680462" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" "unprognostic (2.00e-2)" "unprognostic (2.46e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (2.38e-1)" "unprognostic (5.05e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.94e-1)" "prognostic favorable (6.25e-6)" "unprognostic (2.93e-3)" "unprognostic (1.70e-1)" "unprognostic (5.98e-2)" "unprognostic (7.77e-2)" 8.3 8.9 43.6 2.9 41.0 0.1 7.7 38.9 55.4 12.7 29.7 14.1 3.7 9.2 9.0 6.3 8.9 3.7 11.8 38.3 40.9 9.3 10.0 9.4 4.5 41.5 43.8 9.9 8.4 13.7 18.6 4.2 43.9 12.0 3.8 19.5 8.0 8.1 10.4 9.0 8.3 4.6 45.7 7.8 9.2 4.0 45.1 4.2 11.9 9.2 3.9 10.7 11.6 40.8 2.0 0.6 0.9 2.8 13.7 13.1 1.3 5.1 5.0 1.1 1.5 2.0 1.6 3.8 5.3 6.9 0.6 2.1 1.1 3.1 2.3 3.4 1.9 0.8 3.0 1.5 3.2 1.0 1.3 4.5 7.7 2.2 4.2 8.6 1.4 2.8 0.6 1.5 4.4 1.8 1.2 2.6 0.2 1.6 1.5 1.2 2.4 1.7 6.6 1.8 1.0 1.5 2.8 1.8 3.1 1.0 1.4 3.0 8.8 3.5 0.3 1.2 2.8 3.6 2.5 1.3 3.7 2.6 2.6 0.0 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.2 0.0 43.6 41.0 38.9 55.4 38.3 40.9 41.5 43.8 43.9 45.7 45.1 40.8 6.5 12.8 5.1 14.0 2.3 2.0 2.1 3.2 0.0 21.3 4.5 3.7 14.4 8.6 5.4 3.7 14.6 2.5 1.4 5.5 0.0 3.3 1.9 2.4 3.5 5.4 9.0 0.0 22.2 1.8 1.5 4.4 3.6 2.2 8.2 3.0 7.9 5.9 1.0 28.6 19.8 4.2 0.0 2.2 1.3 1.3 6.5 2.2 7.2 14.0 3.9 5.9 3.1 9.5 17.6 2.8 4.4 17.0 1.3 3.7 7.8 4.2 6.1 8.8 0.0 11.2 5.5 2.4 1.3 1.7 4.0 1.8 1.9 2.8 4.0 2.2 IL11RA ENSG00000137070 "Interleukin 11 receptor subunit alpha" Q14626 9 34650702-34661902 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Craniosynostosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 57.8;Late spermatids: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 36.8;HSkMC: 38.2" "Low region specificity" "Detected in all" "HPA013162, CAB032830, HPA036652" Supported "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB032830: AB_2123745, HPA013162: AB_2668790, HPA036652: AB_2675229" "unprognostic (7.76e-2)" "unprognostic (7.63e-2)" "unprognostic (1.05e-1)" "unprognostic (6.76e-3)" "unprognostic (1.67e-1)" "unprognostic (1.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.52e-2)" "unprognostic (1.89e-2)" "unprognostic (4.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (2.14e-1)" "unprognostic (1.51e-1)" "unprognostic (2.93e-2)" "unprognostic (8.71e-2)" 26.6 14.8 20.0 15.5 22.9 13.7 30.2 23.9 23.8 44.6 17.2 58.0 21.7 32.9 12.2 16.3 36.8 19.5 66.4 20.6 20.4 21.9 50.7 22.6 32.0 21.4 21.5 38.0 12.9 29.2 21.8 10.3 20.4 30.3 11.4 18.7 26.1 15.7 30.0 61.3 37.9 19.6 20.8 33.3 26.0 18.3 21.6 16.9 48.0 28.5 21.1 32.2 34.1 22.9 2.5 5.5 11.7 11.7 16.5 28.9 5.5 13.8 19.1 8.8 11.9 2.0 4.6 2.6 3.7 36.8 3.3 5.0 3.4 5.0 3.5 23.8 9.2 7.9 23.4 1.0 8.4 2.7 4.3 38.2 6.1 4.9 1.7 11.9 5.6 16.4 3.3 5.4 11.3 1.6 3.6 18.6 2.5 2.0 3.7 5.6 2.3 2.7 2.9 2.5 3.4 12.3 1.7 3.7 5.3 6.1 10.1 10.2 5.2 4.1 10.0 3.2 0.0 3.7 2.6 1.0 10.9 3.1 20.1 2.1 1.0 0.0 1.4 1.4 2.1 0.8 2.7 2.2 1.3 1.0 2.5 1.8 0.3 1.0 0.3 0.5 1.7 1.7 20.0 22.9 23.9 23.8 20.6 20.4 21.4 21.5 20.4 20.8 21.6 22.9 15.8 3.2 14.3 26.8 2.6 17.5 5.8 3.6 6.2 19.6 6.4 25.1 37.9 1.5 3.6 3.7 14.6 11.3 5.1 3.7 0.0 1.9 18.3 0.7 4.4 15.2 9.1 0.8 4.3 0.7 4.1 42.7 3.1 1.3 0.0 57.8 17.5 32.1 4.6 23.5 9.0 5.0 0.0 3.5 19.6 97.2 11.1 3.6 32.0 4.7 2.6 15.2 6.2 5.0 7.3 0.3 4.3 5.7 2.4 2.9 7.0 2.4 1.4 9.0 0.0 32.9 8.9 4.6 21.6 1.4 14.1 12.4 6.0 12.2 5.2 1.7 IL17RC IL17-RL ENSG00000163702 "Interleukin 17 receptor C" Q8NAC3 3 9917074-9933630 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.7;myeloid DC: 2.1" "Group enriched" "Detected in many" 18 "dendritic cells: 2.1;monocytes: 1.7" "Cell line enhanced" "Detected in many" "ASC diff: 71.2;ASC TERT1: 43.6;HSkMC: 40.7;T-47d: 41.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019885, CAB026255" Approved "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "CAB026255: , HPA019885: AB_1851664" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.38e-4)" "unprognostic (2.58e-2)" "unprognostic (1.45e-3)" "unprognostic (8.60e-2)" "unprognostic (7.11e-2)" "unprognostic (1.38e-2)" "unprognostic (5.27e-2)" "unprognostic (4.30e-2)" "unprognostic (5.98e-2)" "unprognostic (9.35e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.48e-1)" "unprognostic (2.83e-1)" 17.5 32.2 5.5 4.2 5.5 3.8 18.8 5.0 7.1 16.6 6.0 21.4 15.0 15.0 4.9 23.6 14.8 7.4 19.9 5.7 6.6 15.7 63.7 9.2 1.8 6.2 5.9 12.9 15.3 17.0 27.9 2.9 4.9 31.3 4.7 1.1 23.7 12.6 16.9 32.2 15.5 6.9 6.6 5.9 16.8 1.7 7.0 1.9 13.9 15.7 2.4 17.9 19.4 5.0 7.3 4.6 1.5 4.5 71.2 43.6 10.8 10.0 23.4 12.3 19.5 1.6 19.9 0.0 11.8 15.8 8.7 5.1 2.0 10.7 4.1 4.7 6.0 1.9 13.6 6.6 22.0 0.1 0.0 40.7 8.7 14.9 3.3 5.7 10.6 0.0 0.8 9.1 9.8 11.3 0.2 0.4 0.9 2.6 31.4 4.5 5.1 2.6 9.1 4.1 4.0 6.4 6.1 13.7 10.8 0.4 41.2 0.8 8.9 13.4 6.4 5.9 6.7 0.1 0.3 0.0 21.0 0.9 9.8 0.0 1.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 5.5 5.5 5.0 7.1 5.7 6.6 6.2 5.9 4.9 6.6 7.0 5.0 10.1 0.0 0.5 18.9 2.0 10.8 18.6 11.2 12.5 2.1 30.2 24.1 3.4 18.6 11.7 1.8 0.0 5.8 2.6 22.4 3.9 15.1 0.5 8.0 8.7 7.8 14.4 6.5 3.8 21.1 4.7 15.7 15.8 10.0 0.0 14.0 11.4 43.9 11.0 1.7 4.8 25.3 16.2 6.0 7.8 1.4 19.0 6.0 14.2 4.7 3.4 25.5 1.0 7.1 0.9 13.2 29.8 17.0 1.7 25.7 53.2 17.7 6.9 1.6 19.7 12.8 12.4 0.8 0.5 13.3 19.9 2.9 2.1 11.9 20.0 16.6 IL17RE FLJ23658 ENSG00000163701 "Interleukin 17 receptor E" Q8NFR9 3 9902612-9916402 "Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.8;skin 1: 31.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 92.6;Gastric mucus-secreting cells: 58.1;Intestinal goblet cells: 52.1;Paneth cells: 37.7;Proximal enterocytes: 74.4;Undifferentiated cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 38.5;hTCEpi: 16.5;T-47d: 19.4" "Region enhanced" "Detected in single" "cerebellum: 1.5" HPA019011 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA019011: AB_1851667" "unprognostic (1.08e-2)" "unprognostic (7.58e-2)" "unprognostic (2.06e-1)" "unprognostic (1.43e-3)" "unprognostic (1.09e-1)" "unprognostic (9.81e-2)" "unprognostic (1.50e-1)" "unprognostic (8.43e-2)" "unprognostic (6.69e-2)" "unprognostic (6.31e-2)" "unprognostic (3.55e-3)" "unprognostic (4.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-2)" 6.1 0.4 0.5 1.4 1.6 0.0 5.9 2.2 1.0 4.5 0.3 16.6 20.8 1.8 2.7 7.5 2.5 6.8 1.2 0.4 0.9 2.8 0.8 8.1 0.4 1.5 0.4 0.6 9.7 4.2 1.6 1.1 2.3 4.8 13.8 0.1 6.3 3.3 0.4 31.0 20.4 1.4 0.4 1.0 16.7 0.2 0.3 2.8 3.2 0.2 1.7 1.7 6.6 0.4 2.6 0.3 0.0 0.1 15.5 38.5 11.3 1.0 1.4 0.3 0.9 2.9 2.3 0.0 0.6 2.7 0.0 7.1 0.0 6.2 0.1 0.1 0.1 0.8 0.2 6.8 0.4 0.0 3.2 2.4 16.5 0.0 0.1 0.0 0.1 2.5 0.1 0.0 0.7 3.1 0.4 11.3 0.1 8.1 0.8 0.0 0.0 0.1 2.8 3.2 0.6 0.2 0.0 6.5 0.0 0.3 19.4 0.3 1.5 0.1 0.0 0.3 0.2 0.2 0.1 0.0 0.4 6.5 0.2 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 2.2 1.0 0.4 0.9 1.5 0.4 2.3 0.4 0.3 0.4 3.4 6.4 1.1 3.3 1.0 14.5 11.9 2.3 14.2 3.0 8.4 8.3 0.9 15.7 2.0 16.5 0.0 4.3 0.8 92.6 7.9 2.7 0.2 1.4 2.0 1.3 33.6 9.0 2.4 4.8 1.8 4.9 58.1 1.3 0.0 1.2 1.8 15.4 2.6 1.7 1.9 52.1 2.0 2.2 3.5 0.4 2.1 1.6 5.4 0.0 1.0 4.7 2.1 2.0 0.6 2.5 37.7 3.4 0.8 6.1 74.4 8.0 1.0 1.0 19.7 1.8 7.2 1.6 2.3 11.8 14.8 0.8 2.8 1.0 40.8 4.6 IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 127.1;Endometrial stromal cells: 280.2;Glandular and luminal cells: 315.4;Hepatic stellate cells: 146.7;Langerhans cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 624.9;ASC TERT1: 276.8;HHSteC: 196.3;HSkMC: 770.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1400000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" 137.3 68.0 7.1 69.5 8.3 18.0 77.5 7.5 11.0 161.1 16.2 39.3 20.7 33.5 105.2 32.1 52.0 92.0 58.3 7.6 9.0 45.7 75.5 115.5 17.1 16.2 8.4 31.1 43.3 126.7 13.1 120.8 8.9 66.7 30.5 8.5 34.2 47.4 18.6 40.1 40.3 49.9 10.0 41.0 43.9 20.6 14.9 21.7 52.5 16.0 19.7 87.4 40.2 7.7 2.0 12.8 0.3 10.8 624.9 276.8 4.4 27.4 123.8 19.2 28.7 5.7 3.4 0.0 19.8 55.0 33.9 5.5 0.2 2.2 16.1 55.5 0.1 0.7 2.9 31.3 196.3 0.1 0.3 770.6 2.3 21.7 5.2 8.4 8.7 0.0 3.5 1.1 28.1 5.6 0.0 1.2 0.7 5.6 0.9 0.3 2.0 0.4 18.3 13.4 0.1 0.3 12.5 7.7 0.0 3.6 11.1 0.8 0.3 54.7 3.6 92.1 2.2 0.1 0.0 0.1 21.3 0.6 3.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.6 0.0 7.1 8.3 7.5 11.0 7.6 9.0 16.2 8.4 8.9 10.0 14.9 7.7 99.3 25.6 73.2 1.3 1.8 31.1 46.8 8.2 5.2 0.1 19.4 13.7 5.2 28.6 68.6 5.5 0.0 6.1 2.5 0.7 3.9 31.7 7.0 127.1 280.2 103.6 1.2 14.3 0.5 21.8 82.8 79.1 2.0 315.4 1.3 0.3 146.7 47.1 5.4 0.0 3.0 0.5 10.2 12.0 188.2 12.6 28.0 26.0 19.6 23.4 7.0 9.0 0.0 0.5 0.5 12.0 0.3 1.5 1.8 65.9 0.0 8.3 28.6 1.0 6.6 37.7 34.3 1.3 1.2 4.5 38.6 23.9 8.5 4.0 0.8 23.6 INSYN1 "C15orf59, LOC388135, MGC131524" ENSG00000205363 "Inhibitory synaptic factor 1" Q2T9L4 15 73735458-73753351 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.6;heart muscle: 48.5" "Cell type enriched" "Detected in single" 24 "Cardiomyocytes: 14.7" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 8.7;fHDF/TERT166: 5.8;HEK 293: 3.9;NTERA-2: 3.4;SK-BR-3: 4.7;U-2 OS: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041563 Approved Approved Nucleoplasm,Cytosol No NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "HPA041563: AB_10794670" "unprognostic (2.28e-2)" "unprognostic (2.47e-2)" "unprognostic (4.85e-2)" "unprognostic (2.36e-1)" "unprognostic (1.71e-1)" "unprognostic (9.36e-2)" "unprognostic (3.37e-2)" "unprognostic (1.02e-2)" "unprognostic (1.60e-1)" "unprognostic (8.36e-2)" "unprognostic (2.67e-4)" "unprognostic (2.67e-2)" "prognostic favorable (5.38e-9)" "unprognostic (4.98e-2)" "unprognostic (5.19e-2)" "unprognostic (2.46e-4)" "unprognostic (1.20e-3)" 3.5 2.6 32.6 0.9 30.1 0.1 1.9 27.2 42.8 7.9 1.6 6.6 0.8 4.2 3.4 12.0 7.8 1.9 48.5 38.9 28.8 15.5 0.4 2.7 0.2 26.9 56.6 13.5 1.4 2.9 5.2 0.5 27.7 10.6 0.6 3.9 3.3 11.0 4.6 13.3 2.4 3.2 22.8 0.7 3.7 4.5 46.3 0.2 2.1 2.6 0.9 6.4 16.9 34.7 0.0 0.0 1.8 1.2 8.7 0.1 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.5 5.8 1.0 2.1 1.9 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.5 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.7 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.5 0.4 4.7 0.4 1.3 2.0 0.1 0.0 1.3 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 32.6 30.1 27.2 42.8 38.9 28.8 26.9 56.6 27.7 22.8 46.3 34.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IRAG1 "IRAG, JAW1L, MRVI1" ENSG00000072952 "Inositol 1,4,5-triphosphate receptor associated 1" Q9Y6F6 11 10573091-10693988 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 7.4;Hofbauer cells: 11.1;Smooth muscle cells: 28.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 24.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 24.0" "Cell line enhanced" "Detected in some" "ASC diff: 20.8;BJ: 15.3;BJ hTERT+: 17.6;fHDF/TERT166: 6.9;REH: 6.8" "Region enriched" "Detected in many" 5 "thalamus: 7.6" "Low region specificity" "Detected in all" HPA008704 Uncertain Approved "Nuclear bodies,Cytosol" NA NA 220000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "Nuclear bodies" "HPA008704: AB_1079413" "unprognostic (2.18e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-3)" "prognostic favorable (5.78e-4)" "unprognostic (5.30e-1)" "unprognostic (3.37e-3)" "unprognostic (1.04e-2)" "unprognostic (1.87e-1)" "unprognostic (5.63e-3)" "unprognostic (1.04e-2)" "unprognostic (1.48e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (3.72e-2)" "unprognostic (3.28e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-3)" 29.7 8.0 64.6 18.2 85.8 1.5 16.1 50.4 53.4 55.4 17.7 67.6 8.5 60.8 16.1 37.5 45.6 33.2 10.1 54.5 54.3 9.3 2.1 13.3 3.7 65.8 71.4 20.2 2.9 2.7 3.8 11.8 54.4 37.9 17.3 1.7 4.1 39.5 6.7 9.3 22.0 69.1 55.2 7.1 33.7 8.2 89.8 2.3 10.2 8.1 1.8 43.8 21.9 48.8 0.1 0.0 4.2 0.0 20.8 4.1 0.2 15.3 17.6 0.0 0.0 0.4 1.7 0.0 0.1 6.9 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.7 0.0 0.1 0.2 0.0 0.2 4.8 0.4 0.0 0.1 0.0 1.2 0.0 0.6 0.1 0.3 0.0 0.1 0.3 0.5 0.0 0.1 6.8 0.0 0.3 0.0 0.0 0.0 3.1 0.0 2.6 0.0 4.4 0.0 0.5 0.2 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.3 6.0 0.0 0.7 2.2 1.7 0.0 3.9 0.0 0.8 0.0 0.0 0.6 0.9 0.0 0.0 24.0 0.0 5.7 0.1 0.0 0.7 64.6 85.8 50.4 53.4 54.5 54.3 65.8 71.4 54.4 55.2 89.8 48.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 IRS1 HIRS-1 ENSG00000169047 "Insulin receptor substrate 1" P35568 2 226731312-226799820 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 75.4;Theca cells: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005261, HPA046433" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005261: AB_649615, HPA046433: AB_2732524" "unprognostic (2.20e-1)" "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.59e-2)" "unprognostic (3.86e-3)" "unprognostic (1.61e-1)" "unprognostic (1.44e-1)" "unprognostic (1.80e-3)" "unprognostic (5.47e-2)" "unprognostic (2.24e-2)" "unprognostic (5.48e-3)" "unprognostic (1.10e-1)" "unprognostic (1.36e-3)" "unprognostic (1.46e-2)" "unprognostic (6.92e-2)" "unprognostic (3.23e-2)" "unprognostic (7.55e-3)" 7.6 9.7 1.7 2.9 1.6 0.5 11.7 5.2 3.1 14.7 1.8 10.3 3.9 17.4 1.9 3.6 15.0 5.6 5.0 1.6 1.0 3.4 10.5 5.0 1.7 1.8 1.6 20.9 3.5 3.3 1.5 9.5 1.2 7.8 2.7 1.5 3.0 7.0 28.0 5.2 5.1 10.3 2.0 2.0 5.3 0.8 1.6 8.1 20.0 2.9 1.3 11.6 6.6 1.5 5.7 26.0 18.6 0.7 25.0 14.8 0.0 15.6 12.2 20.4 13.0 15.0 14.4 2.3 2.5 10.6 14.0 10.0 1.2 15.0 11.5 5.9 1.0 0.1 1.7 7.1 12.5 0.5 0.1 20.7 8.1 16.1 14.5 12.3 0.0 2.3 3.0 22.7 14.0 22.6 4.9 6.6 7.5 3.6 14.3 1.1 24.1 0.1 9.3 18.9 3.2 0.5 5.0 3.6 8.4 14.9 13.7 0.3 1.3 26.8 24.2 20.9 15.1 10.6 4.6 3.4 26.5 0.5 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 5.2 3.1 1.6 1.0 1.8 1.6 1.2 2.0 1.6 1.5 1.7 19.2 4.6 5.9 2.7 35.4 31.9 29.7 19.4 19.3 36.9 28.1 13.4 14.3 12.8 0.0 0.0 6.4 0.0 13.2 17.6 15.4 1.6 22.1 28.4 2.1 2.4 0.0 17.3 11.4 0.6 28.3 2.0 24.3 0.0 75.4 1.8 57.4 1.7 20.2 31.3 6.5 24.4 1.3 4.6 1.8 22.7 3.6 16.0 15.0 0.8 8.4 0.0 26.7 1.7 11.1 8.2 14.7 9.5 14.5 23.4 3.0 8.1 1.7 13.1 9.5 22.8 1.0 1.2 4.2 23.7 18.3 1.2 110.3 7.7 22.8 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ISM1 "bA149I18.1, C20orf82" ENSG00000101230 "Isthmin 1" B1AKI9 20 13221274-13300651 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 44.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 19.2;Fibroblasts: 18.4;Microglial cells: 8.4;Proximal tubular cells: 5.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Group enriched" "Detected in some" 5 "ASC diff: 48.9;Hep G2: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA 17000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (7.13e-2)" "unprognostic (3.55e-1)" "unprognostic (4.43e-3)" "unprognostic (5.27e-3)" "unprognostic (1.84e-2)" "unprognostic (5.56e-2)" "unprognostic (2.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (2.06e-1)" "unprognostic (4.48e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (9.32e-6)" "unprognostic (2.58e-2)" "unprognostic (2.10e-1)" "unprognostic (6.83e-2)" "unprognostic (1.81e-2)" 13.2 2.6 1.2 0.3 1.2 0.0 16.6 0.9 1.5 3.3 0.5 2.0 0.4 3.1 0.3 6.6 4.4 4.8 2.9 1.1 3.5 2.1 6.3 4.4 0.3 1.4 1.6 0.5 3.8 0.4 2.1 14.4 1.5 1.6 0.2 0.1 15.2 0.7 1.5 17.0 2.6 1.9 1.3 8.1 3.3 0.1 3.6 4.9 44.4 2.0 0.7 1.3 5.6 0.8 0.0 0.5 0.2 0.7 48.9 6.8 0.3 0.4 4.2 0.0 0.0 2.9 0.4 0.0 0.2 0.0 0.4 0.2 0.0 0.1 0.0 0.0 4.1 0.0 0.0 20.0 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.4 0.0 0.5 0.5 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.1 4.2 0.0 0.0 1.4 0.2 0.9 0.0 0.0 0.0 2.9 0.4 0.1 0.3 0.0 4.7 0.9 0.0 2.3 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 1.2 0.9 1.5 1.1 3.5 1.4 1.6 1.5 1.3 3.6 0.8 1.9 0.0 0.5 0.0 0.0 4.6 0.4 0.4 0.6 0.8 0.5 19.2 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.1 0.2 2.0 2.0 0.0 0.0 0.6 0.0 0.3 18.4 0.0 0.2 0.0 3.4 0.0 2.3 0.5 0.0 4.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 1.8 8.4 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.4 0.1 0.5 0.0 5.2 0.0 0.0 0.0 0.4 1.4 0.0 0.3 0.3 2.8 0.7 0.9 0.0 0.0 0.1 ITFG1 "CDA08, LNKN-1, TIP" ENSG00000129636 "Integrin alpha FG-GAP repeat containing 1" Q8TB96 16 47154387-47464149 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 285.9;Oligodendrocytes: 263.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015590, HPA019728" Approved Approved "Intermediate filaments,Aggresome" "Intracellular and membrane" NA NA 28000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Intermediate filaments" Aggresome "HPA015590: AB_1846347, HPA019728: AB_1846348" "unprognostic (6.53e-3)" "unprognostic (9.26e-3)" "unprognostic (3.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.27e-1)" "unprognostic (1.39e-3)" "unprognostic (3.70e-2)" "unprognostic (9.32e-2)" "unprognostic (2.47e-1)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "prognostic favorable (1.95e-8)" "unprognostic (1.56e-2)" "unprognostic (1.61e-1)" "unprognostic (3.28e-2)" "unprognostic (4.62e-3)" 25.3 42.2 18.5 16.4 23.8 12.5 25.2 17.1 22.0 28.8 26.0 35.1 30.5 27.8 31.2 19.1 26.3 28.8 44.7 23.7 22.9 47.8 45.4 27.4 13.5 13.6 14.0 28.0 27.3 56.0 15.7 40.7 15.9 29.4 33.1 33.3 21.8 28.9 23.8 12.9 26.7 29.1 16.6 19.3 28.3 36.7 18.5 17.2 43.2 24.6 16.7 24.4 13.8 19.5 22.2 24.8 44.0 31.1 84.1 65.0 54.1 50.7 72.9 45.6 24.3 14.2 51.8 25.9 70.4 63.5 30.9 31.9 21.6 33.0 44.9 11.8 17.0 14.0 22.0 33.2 39.4 32.7 59.6 48.3 55.6 23.3 30.1 96.3 44.4 24.2 40.3 33.5 58.3 21.1 20.2 16.3 14.5 27.4 24.5 31.0 43.4 66.5 60.2 15.9 21.9 30.8 46.0 53.6 24.0 43.7 23.7 29.9 43.0 48.9 23.7 26.3 20.7 47.6 66.7 48.4 48.9 20.6 39.2 17.9 33.9 33.4 16.0 33.0 15.2 16.6 19.0 17.7 25.8 17.2 20.7 17.4 21.2 23.8 33.1 17.5 26.1 29.2 18.5 23.8 17.1 22.0 23.7 22.9 13.6 14.0 15.9 16.6 18.5 19.5 38.9 51.3 28.1 165.9 37.2 38.4 43.4 81.3 27.9 50.8 32.6 23.2 56.8 50.1 62.2 82.8 47.9 100.6 32.3 79.3 9.8 60.5 129.0 33.0 28.7 37.8 61.9 27.8 250.7 52.4 86.4 48.5 41.8 35.0 8.2 54.5 39.3 68.7 50.9 40.4 285.9 43.2 73.2 53.8 30.0 32.0 35.1 41.9 28.4 146.1 45.4 39.4 38.1 214.6 263.5 45.3 37.0 61.3 60.1 35.3 65.2 49.6 54.5 47.4 78.9 30.1 49.8 93.7 98.3 25.5 30.3 114.0 29.9 66.0 38.1 37.4 ITIH1 "H1P, IATIH, ITIH" ENSG00000055957 "Inter-alpha-trypsin inhibitor heavy chain 1" P19827 3 52777595-52792068 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 782 "liver: 1504.9" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 1087.0" "Cancer enriched" "Detected in some" 598 "liver cancer: 329.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 5.3;Hep G2: 1.7;HL-60: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041639, HPA042049" Approved Approved Vesicles "Secreted to blood" NA NA 4490000 59000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA041639: AB_10796349, HPA042049: AB_10797379" "unprognostic (1.87e-4)" "unprognostic (1.31e-3)" "unprognostic (2.38e-1)" "unprognostic (8.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.64e-3)" "prognostic favorable (1.89e-5)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-2)" "unprognostic (4.53e-4)" "unprognostic (4.02e-3)" "unprognostic (5.70e-3)" "unprognostic (2.08e-1)" "unprognostic (2.24e-2)" 0.8 0.3 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.2 1504.9 0.1 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 1.9 0.4 0.4 0.0 0.4 0.0 0.1 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.1 0.0 29.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 18.5 1087.0 0.1 0.0 0.0 0.0 0.0 20.2 0.0 1.7 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.1 JAM3 "JAM-C, JAMC" ENSG00000166086 "Junctional adhesion molecule 3" Q9BX67 11 134069071-134152001 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 342.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.3" "Group enriched" "Detected in many" 7 "B-cells: 5.3;T-cells: 2.3" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 99.5;RH-30: 122.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003417, HPA050434" Approved Enhanced "Golgi apparatus" "Secreted to blood" NA NA 44000 "Cluster 43: B-cells - Humoral immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "HPA003417: AB_1851981, HPA050434: AB_2681126" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.38e-2)" "unprognostic (3.24e-1)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.59e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (5.06e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (3.23e-3)" "unprognostic (2.17e-1)" "unprognostic (1.06e-3)" "prognostic unfavorable (2.68e-4)" 23.6 18.7 53.4 10.1 86.3 1.3 19.2 68.7 73.4 33.4 52.9 54.6 6.6 40.8 17.5 21.5 28.7 24.5 31.0 56.5 61.3 11.4 3.2 29.6 7.8 73.5 76.8 48.7 5.1 17.7 33.3 102.7 71.0 32.5 12.9 47.3 13.3 44.5 7.0 13.0 22.5 42.8 59.7 13.5 22.4 35.7 73.3 17.6 15.8 14.6 7.5 41.7 23.4 115.2 0.0 1.0 87.9 42.5 85.3 62.7 75.4 37.0 49.1 15.1 14.8 0.3 0.6 0.0 38.7 53.3 56.2 0.5 70.0 0.7 28.2 0.2 29.6 0.3 0.0 6.9 24.9 0.4 36.2 43.2 0.0 10.7 9.6 35.8 99.5 40.8 0.3 0.2 64.5 1.0 27.5 0.2 18.9 0.6 2.9 0.5 122.8 0.0 0.9 0.2 57.5 32.2 0.0 0.2 1.0 35.3 0.2 0.2 0.6 25.1 18.4 40.3 24.7 0.1 0.1 0.4 27.6 1.2 48.0 0.0 0.0 0.1 1.3 0.0 1.6 5.3 1.6 0.9 0.0 3.1 2.3 1.7 0.5 0.0 0.0 0.0 0.0 1.8 53.4 86.3 68.7 73.4 56.5 61.3 73.5 76.8 71.0 59.7 73.3 115.2 22.2 0.0 6.0 12.7 10.9 5.1 5.6 0.9 0.0 21.7 0.3 9.3 15.7 0.0 0.7 5.5 8.4 6.0 1.2 0.1 1.9 0.4 2.1 0.8 23.3 35.5 0.0 0.4 84.3 0.2 71.2 29.6 1.5 0.5 1.3 11.7 12.5 0.0 8.6 8.4 44.2 0.0 12.2 0.6 4.2 4.9 42.9 10.9 17.8 24.4 0.2 20.2 1.0 76.4 342.8 0.3 0.0 64.3 0.9 2.2 0.0 0.2 1.5 75.6 26.3 19.0 24.3 15.5 19.2 0.2 3.8 6.2 3.5 9.7 0.0 1.0 KANK2 "ANKRD25, KIAA1518, MXRA3" ENSG00000197256 "KN motif and ankyrin repeat domains 2" Q63ZY3 19 11164270-11197791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 402.5;Endometrial stromal cells: 149.6;Leydig cells: 126.2;Peritubular cells: 225.7;Smooth muscle cells: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC diff: 327.8;ASC TERT1: 365.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015643 Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm Cytosol "HPA015643: AB_1844839" "unprognostic (2.37e-1)" "unprognostic (8.03e-2)" "unprognostic (1.15e-2)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" "unprognostic (3.23e-3)" "unprognostic (1.54e-1)" "unprognostic (8.63e-2)" "unprognostic (8.98e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (8.73e-5)" "unprognostic (4.01e-2)" "unprognostic (1.37e-1)" "unprognostic (1.13e-1)" "unprognostic (1.48e-2)" 150.2 55.5 25.7 50.5 27.2 17.9 97.7 22.8 25.6 275.3 24.5 413.2 36.8 376.9 64.6 139.1 222.1 125.0 200.5 20.0 27.9 54.1 51.3 134.5 20.7 29.5 26.5 213.9 35.4 14.3 29.8 62.3 29.0 140.5 58.7 19.0 39.3 173.6 56.9 49.7 108.0 277.7 23.8 57.8 123.7 25.0 29.5 15.7 71.7 51.1 12.4 255.2 148.5 22.6 42.4 91.1 28.3 30.3 327.8 365.1 20.2 188.9 161.0 92.1 76.2 36.3 27.0 177.2 88.1 234.3 59.6 40.0 25.6 13.7 61.3 9.3 18.4 77.2 105.6 37.5 123.9 11.8 21.4 158.7 20.1 67.3 9.0 237.2 37.8 5.5 51.5 14.3 143.6 75.7 2.3 9.9 31.4 27.5 95.1 59.7 234.8 42.2 65.4 22.7 16.6 51.7 188.2 16.4 22.4 32.7 25.1 41.2 139.1 131.5 52.6 170.1 75.2 13.7 32.9 61.3 111.0 66.3 136.4 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 25.7 27.2 22.8 25.6 20.0 27.9 29.5 26.5 29.0 23.8 29.5 22.6 34.1 57.7 28.3 7.8 1.3 6.2 5.5 5.2 2.2 2.0 5.2 7.1 402.5 27.1 12.0 20.2 20.9 6.9 0.6 2.5 3.9 8.1 2.4 12.7 149.6 41.2 0.0 76.2 0.9 4.4 4.9 69.2 13.3 11.9 7.6 7.7 32.5 28.2 22.5 0.0 4.1 2.6 4.1 10.6 15.1 3.8 126.2 6.3 8.8 42.2 0.5 34.9 4.1 1.0 1.4 11.9 1.2 225.7 0.8 6.7 1.6 3.7 8.0 23.4 92.1 79.2 131.0 1.8 7.2 2.8 7.7 2.3 2.3 7.7 5.2 8.4 KCND1 Kv4.1 ENSG00000102057 "Potassium voltage-gated channel subfamily D member 1" Q9NSA2 X 48961378-48971844 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 3.5;Peritubular cells: 3.8;Rod photoreceptor cells: 3.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 10.6;NB-4: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000524, HPA001066" Supported Uncertain Nucleoplasm Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA000524: AB_2666013, HPA001066: AB_1079662" "unprognostic (6.00e-2)" "unprognostic (2.58e-1)" "unprognostic (1.01e-4)" "unprognostic (2.19e-4)" "unprognostic (1.41e-1)" "unprognostic (3.79e-2)" "unprognostic (2.79e-1)" "unprognostic (8.13e-3)" "unprognostic (1.13e-2)" "unprognostic (2.41e-3)" "prognostic favorable (2.66e-6)" "unprognostic (2.61e-1)" "unprognostic (4.30e-11)" "unprognostic (3.13e-2)" "unprognostic (3.49e-1)" "unprognostic (7.64e-2)" "unprognostic (2.22e-3)" 3.8 0.9 2.8 1.5 2.8 2.7 1.8 5.5 2.7 2.7 0.1 2.0 0.8 3.6 1.4 1.1 5.4 2.4 2.3 2.9 3.0 1.7 1.4 2.6 1.3 3.6 2.9 2.7 1.1 0.4 2.3 1.0 3.9 2.3 0.8 6.1 0.9 2.1 0.5 1.3 2.2 2.5 3.3 3.3 1.8 1.5 3.2 0.7 1.8 0.4 1.4 2.3 2.3 3.8 0.3 1.6 0.7 3.9 5.1 4.1 1.3 0.8 3.3 2.3 1.5 1.1 0.5 1.3 2.8 2.6 0.6 0.5 0.6 0.3 2.2 2.3 2.7 1.2 1.8 0.1 1.9 0.3 2.5 10.6 1.4 4.2 0.4 3.7 0.8 1.9 0.9 3.0 1.7 3.1 0.4 9.2 2.1 0.2 0.6 1.1 0.7 1.3 2.6 1.3 0.4 1.8 0.7 0.0 1.8 7.9 1.7 1.3 2.0 0.5 2.1 0.5 0.2 2.5 3.5 3.2 1.4 3.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.8 2.8 5.5 2.7 2.9 3.0 3.6 2.9 3.9 3.3 3.2 3.8 0.9 0.0 1.1 1.0 0.4 0.8 0.0 0.4 0.0 0.2 0.3 0.3 0.8 0.0 0.2 1.8 0.0 0.1 0.4 0.3 1.9 0.2 0.1 0.2 1.0 0.6 3.5 0.0 0.7 0.0 0.1 1.2 0.5 0.5 0.0 1.7 1.1 0.0 0.1 0.0 1.1 0.3 0.0 0.6 0.0 0.2 1.8 0.4 0.0 1.0 0.1 0.4 0.0 2.0 0.1 0.1 0.0 3.8 0.1 0.2 0.2 0.1 0.3 3.0 0.0 0.1 0.6 0.6 0.0 0.1 0.0 0.1 0.2 0.1 0.2 0.2 KCTD10 "BTBD28, MSTP028" ENSG00000110906 "Potassium channel tetramerization domain containing 10" Q9H3F6 12 109448655-109477359 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014273 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA014273: AB_1852159" "unprognostic (7.21e-3)" "unprognostic (3.04e-1)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "unprognostic (1.93e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (5.32e-4)" "unprognostic (1.84e-2)" "unprognostic (1.85e-1)" "unprognostic (7.01e-2)" "unprognostic (9.33e-2)" "unprognostic (3.45e-1)" "unprognostic (7.72e-2)" "unprognostic (5.76e-2)" "unprognostic (3.26e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" 40.3 23.4 20.5 26.2 19.7 15.4 32.9 17.2 20.3 34.2 32.1 42.5 14.7 43.8 14.0 36.6 27.4 33.0 24.1 19.7 31.0 23.0 11.4 31.9 21.9 21.1 23.1 18.1 12.4 22.2 17.0 25.4 26.6 29.2 33.2 14.3 20.7 44.3 11.5 30.3 22.3 57.0 19.2 23.2 25.8 16.3 30.1 14.9 47.1 11.7 22.8 39.0 29.4 18.9 28.4 27.9 84.6 27.5 67.8 91.2 18.5 59.0 80.2 38.8 38.2 28.1 23.1 27.5 34.0 136.4 19.2 22.0 30.7 51.6 35.9 26.0 22.0 32.3 19.2 19.3 44.5 24.9 26.7 92.2 30.7 50.0 29.3 54.7 89.5 26.4 21.5 11.5 68.0 15.1 29.8 32.9 48.1 12.7 36.0 29.2 37.7 22.6 38.5 48.9 29.5 44.3 35.6 38.8 41.8 47.5 45.2 18.8 70.0 42.3 15.5 24.0 32.8 26.0 52.8 37.1 48.8 20.2 60.5 10.9 9.5 6.4 13.5 14.4 10.1 6.6 8.0 10.0 11.9 6.2 8.8 11.1 6.5 25.1 17.2 9.0 10.0 14.9 20.5 19.7 17.2 20.3 19.7 31.0 21.1 23.1 26.6 19.2 30.1 18.9 21.1 16.0 29.9 6.2 9.0 14.7 20.1 17.4 11.4 5.4 12.1 13.5 11.5 10.0 13.7 5.5 16.7 9.1 19.4 31.5 5.9 15.3 12.2 9.9 17.8 26.8 11.5 6.5 9.8 13.1 12.8 15.5 10.7 12.8 14.0 11.3 24.7 5.3 11.5 8.4 8.1 13.4 10.2 13.6 13.3 11.3 11.5 14.6 16.0 8.4 15.7 2.8 81.4 8.0 9.4 25.9 11.8 18.8 7.5 12.2 6.4 10.5 12.2 4.4 26.3 13.4 32.6 13.5 6.3 10.2 16.6 13.5 10.6 10.4 15.0 18.1 KDELR2 "ELP-1, ERD2.2" ENSG00000136240 "KDEL endoplasmic reticulum protein retention receptor 2" P33947 7 6445953-6484190 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 786.7;Extravillous trophoblasts: 944.9;Syncytiotrophoblasts: 759.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016459 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "HPA016459: AB_1852180" "unprognostic (2.16e-3)" "unprognostic (1.34e-3)" "unprognostic (1.77e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.40e-5)" "prognostic unfavorable (1.03e-5)" "unprognostic (1.85e-2)" "unprognostic (7.05e-2)" "unprognostic (1.42e-1)" "unprognostic (1.95e-1)" "unprognostic (2.33e-2)" "unprognostic (5.42e-1)" "prognostic unfavorable (6.79e-8)" "unprognostic (7.72e-2)" "unprognostic (1.80e-1)" "unprognostic (4.29e-2)" "unprognostic (2.71e-2)" 83.9 70.6 31.2 67.1 32.7 25.5 84.6 33.8 35.5 132.5 53.0 132.8 117.6 82.9 119.2 63.4 68.3 85.0 74.2 30.5 33.8 81.4 229.6 73.2 36.3 34.2 32.0 64.9 99.6 68.2 70.7 148.4 34.1 107.0 144.2 23.6 103.8 84.2 40.4 52.4 119.1 106.3 33.6 44.2 155.6 64.0 34.7 24.9 98.3 44.4 52.1 91.7 58.6 35.5 280.7 121.6 116.4 223.0 558.2 512.4 116.0 415.2 374.8 236.5 353.8 197.0 180.6 44.7 113.0 591.3 352.8 245.8 169.9 173.1 365.1 24.6 97.6 55.0 120.0 271.6 338.4 84.0 72.4 327.8 171.8 230.7 272.3 263.8 217.5 42.2 123.4 128.2 325.4 234.7 25.8 80.9 112.8 358.0 181.5 61.5 180.6 117.6 190.6 116.2 108.5 130.2 172.7 304.6 135.2 177.8 252.3 144.7 189.0 180.0 262.4 439.6 223.4 93.9 84.4 76.8 299.5 162.8 525.7 77.8 72.0 77.0 47.6 74.8 61.0 44.0 49.0 52.5 72.0 43.6 39.4 43.3 47.2 43.5 77.8 127.3 49.1 56.9 31.2 32.7 33.8 35.5 30.5 33.8 34.2 32.0 34.1 33.6 34.7 35.5 110.2 25.6 71.0 17.9 109.7 192.2 175.5 239.0 67.7 26.7 141.6 82.4 60.6 117.2 159.5 62.5 12.5 417.9 86.9 261.0 35.2 217.2 786.7 59.2 152.5 136.4 114.3 100.1 22.5 323.5 944.9 262.9 170.2 121.4 68.6 75.7 119.6 377.8 300.9 32.0 29.5 492.7 89.5 91.7 210.8 115.9 151.3 112.4 177.9 37.5 99.2 31.2 58.7 29.7 24.5 224.8 232.9 121.9 486.7 427.2 244.1 113.5 87.7 31.2 72.3 89.4 177.1 527.9 149.8 122.4 198.9 759.9 73.2 136.1 279.6 319.1 KLF15 KKLF ENSG00000163884 "Kruppel like factor 15" Q9UIH9 3 126342635-126357408 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 92.5" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;Cardiomyocytes: 29.7;Distal tubular cells: 29.4;Hepatocytes: 66.9;Peritubular cells: 19.9;Proximal tubular cells: 22.1" "Cancer enhanced" "Detected in many" "liver cancer: 30.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 57.4;HHSteC: 34.8;RPMI-8226: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003286, HPA028866" Uncertain Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Nuclear speckles" Vesicles "HPA003286: , HPA028866: AB_10600819" "unprognostic (3.77e-3)" "unprognostic (1.08e-1)" "unprognostic (1.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.72e-3)" "unprognostic (2.11e-1)" "unprognostic (4.63e-2)" "unprognostic (1.09e-2)" "unprognostic (2.91e-1)" "unprognostic (1.32e-1)" "unprognostic (3.58e-2)" "unprognostic (1.10e-1)" "prognostic favorable (3.27e-7)" "unprognostic (6.75e-2)" "unprognostic (7.65e-2)" "unprognostic (1.91e-2)" "unprognostic (5.58e-3)" 36.5 6.2 42.2 0.8 50.7 0.1 25.4 45.1 69.5 15.8 37.5 18.6 1.2 19.1 4.1 7.1 29.7 3.5 31.4 41.7 40.6 20.3 92.5 18.6 1.8 64.9 45.9 46.3 48.5 4.5 10.4 1.7 47.2 17.6 0.9 3.9 19.7 5.2 67.3 10.3 10.2 2.5 44.9 3.6 30.2 5.6 44.7 1.2 11.1 32.4 0.8 27.0 12.0 48.4 0.8 0.0 2.2 9.2 57.4 1.0 10.0 0.6 1.4 0.7 1.3 1.1 0.0 3.4 0.9 0.0 1.7 0.1 5.3 0.1 0.2 0.2 2.0 0.1 0.8 7.9 34.8 0.0 0.2 5.4 0.5 0.0 1.2 0.0 0.6 4.5 4.3 7.4 0.2 0.7 0.0 1.3 6.6 1.3 0.3 4.7 0.2 20.2 0.1 0.8 0.7 7.7 0.1 0.3 10.2 3.3 0.5 4.6 0.3 0.3 0.4 0.3 0.3 4.7 0.6 0.7 0.2 1.5 1.3 25.1 7.6 10.3 7.0 10.2 8.2 12.3 7.3 7.4 8.2 11.4 9.4 11.3 16.7 12.8 9.3 9.0 10.5 11.7 42.2 50.7 45.1 69.5 41.7 40.6 64.9 45.9 47.2 44.9 44.7 48.4 1.5 6.4 4.6 22.9 0.8 0.0 2.9 0.2 0.6 1.3 7.8 1.8 29.7 15.7 0.7 0.0 0.0 0.1 0.1 0.0 29.4 0.1 0.1 2.5 4.4 2.1 0.0 2.7 0.6 0.0 0.2 8.1 3.1 3.4 0.0 13.7 8.2 66.9 0.1 0.0 2.8 0.1 0.0 2.6 0.0 0.8 12.2 0.4 1.8 2.8 0.0 12.0 0.0 15.1 5.7 0.4 0.0 19.9 0.9 5.2 0.0 22.1 0.8 3.3 0.0 12.0 5.5 0.1 0.1 0.3 0.0 0.3 0.5 0.6 0.1 1.8 KLF9 BTEB1 ENSG00000119138 "Kruppel like factor 9" Q13886 9 70384597-70414624 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 264.3;Skeletal myocytes: 223.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 60.4;ASC TERT1: 83.0;HHSteC: 107.4;HSkMC: 71.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029308 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane, Cytosol" "HPA029308: AB_10601923" "unprognostic (2.12e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (2.69e-2)" "unprognostic (5.86e-2)" "unprognostic (1.37e-1)" "unprognostic (3.64e-3)" "unprognostic (4.34e-1)" "unprognostic (5.55e-1)" "unprognostic (9.47e-2)" "unprognostic (7.86e-2)" "unprognostic (3.44e-1)" "prognostic favorable (6.59e-6)" "unprognostic (1.43e-3)" "unprognostic (1.75e-1)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" 82.0 36.5 12.5 22.8 22.1 18.2 67.6 29.8 22.5 29.9 14.9 66.5 15.3 56.5 16.7 41.1 73.0 42.6 54.7 15.7 14.4 54.9 91.3 71.6 14.4 21.3 21.1 63.4 52.9 51.1 25.5 10.2 17.3 36.5 26.2 19.2 35.4 24.4 123.3 40.8 33.2 58.9 15.6 22.9 48.9 7.7 21.7 12.1 57.1 94.7 14.3 43.4 37.2 19.1 0.4 0.6 0.0 7.8 60.4 83.0 0.8 4.1 27.1 1.4 3.0 0.1 3.6 0.1 3.0 7.5 2.0 0.1 11.9 18.4 2.8 0.0 9.3 4.2 13.1 2.4 107.4 2.1 10.9 71.6 18.4 1.1 25.9 37.1 23.9 1.8 8.4 16.4 10.2 1.3 0.3 6.2 0.7 1.2 3.9 0.0 3.7 10.9 5.0 0.0 1.0 5.2 37.3 21.5 45.2 2.5 7.1 6.7 32.8 7.1 5.1 8.2 2.2 11.8 13.5 0.6 6.4 6.6 35.9 0.7 0.1 0.1 0.4 0.1 0.6 0.9 0.5 0.4 0.3 0.6 0.7 0.4 0.0 0.1 0.2 0.4 0.6 0.1 12.5 22.1 29.8 22.5 15.7 14.4 21.3 21.1 17.3 15.6 21.7 19.1 264.3 41.7 25.5 25.8 36.5 48.2 62.7 13.0 97.3 45.3 48.3 34.7 74.1 64.3 22.3 14.7 20.9 0.2 51.0 36.7 31.3 10.5 22.3 40.6 171.6 124.3 13.8 14.5 32.1 13.1 0.5 180.8 55.5 59.6 7.6 2.0 109.9 158.8 3.7 80.8 13.7 32.3 14.2 70.1 44.6 18.1 90.7 81.3 39.2 29.0 9.7 126.1 19.6 3.0 11.1 12.8 26.1 85.0 30.2 74.0 54.5 39.7 17.4 10.1 78.9 223.8 203.5 2.1 3.2 72.7 34.2 0.0 54.9 16.3 31.9 33.3 KLHDC1 MST025 ENSG00000197776 "Kelch domain containing 1" Q8N7A1 14 49693105-49753150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 46.4;Excitatory neurons: 41.7;Inhibitory neurons: 51.1;Microglial cells: 49.6;Oligodendrocyte precursor cells: 45.2;Oligodendrocytes: 90.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 5.7;ASC TERT1: 5.3;HSkMC: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020461 Approved Supported Cytosol No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA020461: AB_1852556" "unprognostic (2.97e-2)" "unprognostic (6.30e-2)" "unprognostic (8.49e-3)" "unprognostic (1.26e-2)" "unprognostic (5.46e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-1)" "unprognostic (1.95e-2)" "unprognostic (1.01e-1)" "unprognostic (2.53e-1)" "prognostic favorable (1.94e-4)" "unprognostic (3.42e-1)" "unprognostic (5.61e-2)" "unprognostic (3.14e-2)" "unprognostic (1.13e-1)" "unprognostic (8.45e-2)" "unprognostic (2.24e-1)" 5.2 4.2 3.3 2.3 5.1 1.4 4.8 4.5 6.0 6.2 1.5 5.5 1.9 6.0 5.7 2.2 5.8 3.1 4.6 2.8 5.4 3.1 3.5 3.1 3.6 5.0 4.2 9.3 3.8 4.1 6.2 2.6 4.3 4.6 2.3 6.0 3.3 4.3 7.2 5.1 3.8 3.5 3.1 3.8 3.9 4.8 4.0 1.9 5.6 4.7 2.6 4.4 4.8 7.4 0.7 0.3 0.6 0.3 5.7 5.3 0.0 1.5 2.1 0.5 0.3 0.0 1.8 0.3 0.3 0.6 0.5 0.5 0.1 0.0 0.4 1.5 0.5 0.2 0.1 0.0 2.9 0.1 0.7 4.5 0.2 0.2 0.2 2.9 1.2 1.0 0.3 0.0 2.2 0.2 0.4 0.8 0.0 0.2 0.2 0.4 0.5 0.0 1.1 0.2 0.2 1.5 0.2 0.0 0.6 0.7 0.6 1.2 1.7 1.3 1.4 0.5 0.1 0.5 0.0 0.4 1.2 0.2 0.7 0.5 0.4 1.0 0.7 0.8 1.4 1.2 1.0 0.9 0.4 0.8 1.7 1.4 0.0 0.6 0.4 1.4 0.3 0.7 3.3 5.1 4.5 6.0 2.8 5.4 5.0 4.2 4.3 3.1 4.0 7.4 7.6 22.4 6.5 46.4 6.1 3.6 3.4 1.5 4.0 10.4 3.3 2.3 10.1 5.7 5.7 0.0 4.2 1.5 2.7 1.7 9.8 0.8 2.1 3.5 5.4 5.7 1.8 5.2 41.7 0.8 0.8 7.3 2.6 1.9 1.3 4.5 4.6 3.2 2.6 13.5 51.1 2.4 2.0 2.2 3.3 3.3 18.0 2.9 5.4 49.6 2.2 15.0 4.1 45.2 90.5 0.4 2.7 10.1 2.9 1.6 4.2 2.5 3.1 15.8 0.0 9.5 6.1 17.9 7.6 1.3 3.3 0.3 3.7 4.2 1.2 1.8 KLHL20 "KHLHX, KLEIP" ENSG00000076321 "Kelch like family member 20" Q9Y2M5 1 173714941-173786692 "Predicted intracellular proteins" "Protein transport, Transport, Ubl conjugation pathway" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025034, HPA053704" Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Cytosol" "HPA025034: AB_1852578, HPA053704: AB_2682234" "unprognostic (2.97e-3)" "unprognostic (3.11e-2)" "unprognostic (8.27e-2)" "unprognostic (6.48e-3)" "unprognostic (1.56e-2)" "unprognostic (1.50e-1)" "unprognostic (2.51e-1)" "unprognostic (3.55e-2)" "unprognostic (1.84e-2)" "unprognostic (2.14e-2)" "unprognostic (5.22e-2)" "unprognostic (1.03e-1)" "unprognostic (3.51e-2)" "unprognostic (8.66e-2)" "unprognostic (3.02e-1)" "unprognostic (1.90e-1)" "unprognostic (2.62e-2)" 13.8 10.2 5.8 7.6 7.1 5.9 8.7 7.3 6.7 11.8 4.7 9.7 6.7 13.6 6.9 9.8 8.1 9.3 10.8 6.5 6.3 10.8 16.2 10.0 9.7 7.4 6.7 12.0 6.0 7.9 5.3 11.4 7.1 13.1 8.9 9.0 6.1 9.3 12.5 9.5 7.8 13.4 6.9 10.3 7.5 15.9 6.5 12.3 8.4 13.9 9.1 10.0 8.2 6.9 12.8 8.0 12.5 13.1 28.7 26.4 10.2 19.7 19.2 14.9 15.6 5.8 8.7 9.0 16.4 21.3 7.9 12.5 11.2 14.2 17.4 11.0 6.0 8.2 10.8 6.9 18.4 15.5 9.3 22.6 16.1 13.8 18.4 17.3 22.2 9.0 18.5 10.0 27.6 4.7 9.1 8.0 13.3 11.3 36.1 9.7 15.4 9.8 11.4 8.1 5.3 14.7 18.0 12.1 12.3 16.9 10.8 18.0 22.2 14.3 8.6 17.6 15.7 13.3 7.4 13.5 9.4 11.0 16.2 7.0 2.9 4.3 4.5 3.2 4.0 3.6 4.4 5.5 2.8 3.5 5.6 5.7 1.6 3.2 2.4 4.6 5.6 2.3 5.8 7.1 7.3 6.7 6.5 6.3 7.4 6.7 7.1 6.9 6.5 6.9 21.8 16.0 25.9 36.2 17.3 11.1 8.1 13.5 8.0 13.3 8.0 8.0 12.8 17.2 12.8 12.9 37.5 13.1 18.1 13.5 1.9 9.9 132.4 4.4 14.0 23.4 9.6 11.1 28.1 12.1 10.1 18.2 16.3 5.6 7.6 14.9 42.1 21.0 11.2 11.8 37.3 9.1 10.2 18.5 9.1 30.2 22.4 10.0 3.6 18.7 9.4 16.4 20.6 33.7 35.2 11.4 8.9 28.6 12.3 8.8 16.3 14.1 8.2 20.7 0.0 20.9 16.4 55.8 35.6 11.3 10.5 9.9 16.9 24.1 9.7 7.8 LAMA2 LAMM ENSG00000196569 "Laminin subunit alpha 2" P24043 6 128883138-129516566 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 106.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 363.1;Fibroblasts: 151.1;Leydig cells: 184.2;Microglial cells: 692.3;Oligodendrocytes: 160.9;Peritubular cells: 224.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 255.1;ASC TERT1: 184.5;HHSteC: 55.5;HSkMC: 156.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB040310, CAB078182" Enhanced "Secreted to extracellular matrix" NA NA 55000000 "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB040310: , CAB078182: AB_2665829" "unprognostic (1.17e-1)" "unprognostic (5.87e-2)" "unprognostic (2.17e-2)" "unprognostic (3.17e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (9.73e-2)" "unprognostic (3.67e-2)" "unprognostic (2.44e-3)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (4.04e-2)" "unprognostic (1.24e-3)" "unprognostic (6.16e-2)" "unprognostic (5.41e-3)" "prognostic unfavorable (3.65e-5)" 37.6 9.2 2.7 2.6 10.2 0.0 25.0 4.1 5.8 24.1 10.8 14.8 1.7 17.1 4.1 8.0 34.9 18.0 64.0 1.8 3.4 4.1 4.4 26.5 1.0 13.8 4.6 53.4 8.0 2.8 6.9 106.0 8.3 7.3 4.7 2.5 14.9 9.0 22.0 14.1 13.7 14.2 4.7 5.0 17.4 9.2 7.5 2.7 14.6 42.9 0.7 18.1 18.1 6.4 0.0 0.1 2.8 0.1 255.1 184.5 0.0 26.1 9.5 0.6 0.6 0.0 0.2 0.0 0.3 28.2 0.2 0.1 1.6 0.1 0.6 0.1 0.0 0.1 0.0 0.0 55.5 0.0 0.3 156.4 0.1 13.5 0.3 0.2 0.3 0.0 0.0 1.0 44.1 0.0 0.0 0.1 0.5 0.8 0.0 0.0 14.5 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 22.2 1.4 0.1 0.3 8.9 0.3 0.0 1.7 0.0 2.9 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 2.7 10.2 4.1 5.8 1.8 3.4 13.8 4.6 8.3 4.7 7.5 6.4 7.7 0.0 0.5 24.8 0.0 3.7 2.2 0.5 1.2 1.3 1.1 0.8 90.7 0.0 0.9 0.0 0.0 2.1 0.5 0.0 0.0 1.4 7.5 6.5 75.1 8.5 0.0 0.0 363.1 0.2 1.9 151.1 11.7 6.5 0.0 1.0 3.6 0.0 3.0 0.0 8.6 0.0 0.0 0.0 4.4 11.7 184.2 1.9 1.8 692.3 0.1 11.1 3.1 8.0 160.9 0.9 0.0 224.2 0.5 1.0 0.0 0.6 4.5 1.1 118.3 122.1 8.8 2.6 1.9 1.2 2.8 3.8 1.7 44.5 0.0 1.1 LAMC1 LAMB2 ENSG00000135862 "Laminin subunit gamma 1" P11047 1 183023420-183145592 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 231.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1582.4;ASC TERT1: 863.5;HSkMC: 980.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001908, HPA001909, CAB004486, CAB078163" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to extracellular matrix" NA NA 100000000 "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum, Plasma membrane" "CAB004486: AB_627870, CAB078163: AB_2665817, HPA001908: AB_1079229, HPA001909: AB_1079230" "unprognostic (1.46e-1)" "unprognostic (1.05e-2)" "unprognostic (8.30e-2)" "unprognostic (8.84e-3)" "unprognostic (3.75e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.38e-2)" "unprognostic (2.71e-2)" "unprognostic (1.10e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-3)" "unprognostic (1.10e-3)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.85e-5)" 117.2 16.4 6.3 34.9 7.2 1.1 79.3 9.2 7.1 55.1 13.8 78.3 16.0 63.2 19.3 44.5 63.8 54.7 61.7 7.2 8.7 19.4 13.8 58.7 15.3 6.9 7.7 36.1 19.2 20.0 9.5 231.7 6.0 31.3 34.3 3.7 28.1 50.9 50.5 40.8 48.9 102.3 6.4 8.4 51.1 18.7 8.6 14.7 40.3 60.1 12.0 66.9 47.7 5.4 52.5 83.5 268.4 76.7 1582.4 863.5 405.0 374.8 373.0 147.8 87.1 249.4 58.2 18.8 168.6 180.8 87.9 127.4 51.7 99.2 112.7 0.6 52.6 0.9 71.1 91.3 248.1 16.6 8.9 980.4 52.2 177.0 138.7 262.7 261.0 0.2 0.6 55.5 182.5 22.8 0.2 17.4 109.3 96.0 15.7 13.5 226.2 9.9 237.6 137.0 17.6 50.1 98.9 0.7 95.6 459.0 21.2 43.6 486.5 179.1 70.0 168.2 95.4 21.6 0.3 12.4 148.7 12.3 177.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 7.2 9.2 7.1 7.2 8.7 6.9 7.7 6.0 6.4 8.6 5.4 81.2 35.3 21.6 32.7 8.1 31.4 46.1 44.4 35.9 3.1 7.1 17.4 57.5 27.1 21.0 36.8 4.2 101.9 0.2 1.6 1.9 59.2 5.7 32.5 58.5 80.9 1.2 0.0 69.2 23.3 69.0 187.8 8.6 78.5 2.5 53.0 26.7 19.1 18.7 1.7 50.0 2.4 18.3 10.7 20.6 6.8 120.9 4.5 33.8 106.8 6.0 2.2 1.0 35.2 2.5 44.7 2.6 62.4 11.0 59.9 0.5 12.4 14.8 0.7 72.3 73.9 102.1 17.6 36.8 17.0 16.9 72.1 2.8 74.4 3.5 25.8 LAPTM4A "HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp" ENSG00000068697 "Lysosomal protein transmembrane 4 alpha" Q15012 2 20032650-20051628 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 1393.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031402, HPA031404, HPA068554" Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "Plasma membrane" "HPA031402: AB_10669882, HPA031404: AB_10670293, HPA068554: AB_2686003" "unprognostic (2.01e-1)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (5.73e-1)" "unprognostic (6.04e-2)" "unprognostic (3.00e-2)" "unprognostic (1.53e-3)" "unprognostic (5.37e-2)" "unprognostic (1.27e-1)" "unprognostic (3.65e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (8.70e-2)" "unprognostic (1.05e-2)" "unprognostic (7.78e-3)" "unprognostic (2.18e-2)" "unprognostic (7.98e-3)" "unprognostic (2.36e-1)" 360.5 451.0 116.8 177.1 114.9 199.5 338.5 120.7 146.8 469.8 150.8 256.2 219.6 507.6 339.7 315.4 370.1 383.7 322.5 112.7 130.2 460.9 409.2 308.0 160.1 123.3 122.2 460.3 290.8 289.2 155.6 397.6 128.1 306.3 233.9 59.1 306.0 611.8 204.4 247.2 227.7 412.2 130.1 190.9 240.5 389.3 125.5 122.8 365.8 234.8 178.5 342.1 248.7 128.0 417.7 228.8 136.4 283.2 1393.4 1031.8 509.1 514.3 651.8 349.3 393.6 180.5 398.4 73.2 116.2 637.9 356.9 400.7 115.0 250.6 317.8 181.2 183.2 112.4 244.3 520.1 534.8 86.7 294.9 691.7 501.2 338.7 386.4 481.9 367.6 62.2 86.6 135.8 527.5 243.3 53.8 114.0 299.2 353.1 207.1 89.3 397.5 139.7 858.6 347.7 214.8 207.3 480.4 390.5 335.9 492.9 169.6 70.1 467.5 575.7 203.8 500.3 336.5 221.7 349.2 118.3 455.3 172.8 234.4 737.8 382.3 289.3 94.6 324.9 116.4 197.4 112.9 106.9 269.2 192.3 126.7 113.7 200.1 124.3 393.4 226.9 119.3 427.0 116.8 114.9 120.7 146.8 112.7 130.2 123.3 122.2 128.1 130.1 125.5 128.0 351.7 195.5 203.1 39.2 156.5 659.0 601.1 1210.5 339.2 24.4 330.3 306.1 211.7 380.3 727.7 553.6 12.5 224.4 109.8 174.8 162.4 539.4 1235.7 195.7 407.1 384.0 138.1 65.0 15.0 347.6 1035.3 896.8 111.6 286.0 521.9 445.7 331.3 519.4 311.3 20.2 14.3 203.6 767.0 299.3 716.0 1080.9 835.3 254.4 588.7 39.4 278.0 315.3 48.4 34.7 18.7 289.4 246.2 600.7 156.8 331.2 171.5 940.9 506.7 24.7 532.5 389.4 583.0 356.3 173.5 268.2 709.8 302.9 146.4 579.1 224.8 500.9 LBP BPIFD2 ENSG00000129988 "Lipopolysaccharide binding protein" P18428 20 38346482-38377013 "Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity, Lipid transport, Transport" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 1338.5" "Cell type enriched" "Detected in some" 30 "Hepatocytes: 458.3" "Cancer enriched" "Detected in many" 20 "liver cancer: 356.7" "Region enhanced" "Detected in single" "medulla oblongata: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 10.7;HSkMC: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001508, CAB025905" Approved "Secreted to blood" NA NA 25000000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB025905: , HPA001508: AB_1079241" "unprognostic (4.20e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (4.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-2)" "unprognostic (5.50e-2)" "unprognostic (2.48e-3)" "unprognostic (6.15e-2)" "unprognostic (2.12e-1)" "unprognostic (7.93e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (3.62e-12)" "prognostic unfavorable (5.76e-4)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" 58.2 0.5 0.0 24.2 0.1 0.5 6.6 0.0 0.2 4.6 0.0 0.5 0.0 2.6 0.0 0.1 0.6 0.2 3.3 0.0 0.0 8.7 1338.5 1.2 2.8 1.1 0.1 0.2 1.7 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.4 0.0 22.8 0.6 0.6 1.5 0.0 0.5 0.6 0.7 0.4 0.1 3.9 2.0 0.3 0.7 0.2 0.3 0.0 0.1 0.1 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 8.6 0.7 0.0 0.0 0.1 0.0 0.0 7.9 0.8 1.0 0.1 0.2 0.5 0.0 10.7 0.3 11.0 0.1 0.8 0.0 0.7 0.0 0.0 9.7 458.3 0.3 0.0 0.3 0.0 0.0 8.5 0.0 0.3 0.6 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 15.2 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 LHFPL6 "LHFP, MGC22429" ENSG00000183722 "LHFPL tetraspan subfamily member 6" Q9Y693 13 39209116-39603528 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 195.2;Endometrial stromal cells: 78.1;Extravillous trophoblasts: 156.9;Fibroblasts: 113.0;Smooth muscle cells: 131.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "myeloid DC: 6.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.2" "Cell line enhanced" "Detected in many" "ASC diff: 255.1;HSkMC: 186.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058975 Approved Approved Nucleoli NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli "HPA058975: AB_2683866" "unprognostic (6.98e-2)" "unprognostic (2.71e-1)" "unprognostic (2.00e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (4.10e-2)" "unprognostic (5.84e-2)" "unprognostic (1.08e-1)" "unprognostic (2.76e-1)" "unprognostic (5.45e-2)" "unprognostic (8.68e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (1.20e-7)" "unprognostic (4.41e-3)" "unprognostic (5.25e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (2.30e-4)" 143.2 55.1 46.3 18.6 49.9 1.1 128.7 59.2 45.2 51.6 57.2 51.7 10.8 78.8 47.5 37.0 88.9 74.5 99.7 45.6 57.3 31.9 14.2 82.6 39.1 54.9 56.8 49.6 17.2 18.2 26.9 134.6 51.4 30.8 16.7 11.9 34.7 36.9 32.1 37.9 29.0 68.9 47.8 30.4 27.9 20.4 64.3 17.0 64.2 89.2 17.6 49.1 48.3 44.3 11.5 4.0 118.3 5.1 255.1 115.1 51.6 61.8 88.3 30.8 23.1 0.5 11.6 17.5 1.3 86.6 40.0 17.3 15.0 36.2 25.3 16.9 17.2 47.3 3.7 0.0 26.7 0.8 0.9 186.4 4.7 27.7 45.7 27.6 29.1 1.1 0.0 0.1 59.9 9.9 0.0 14.5 8.8 0.2 15.8 7.7 51.3 0.1 20.9 15.0 0.7 3.8 5.6 7.2 16.8 67.4 6.7 0.1 54.3 77.9 11.7 24.4 33.9 0.9 0.0 48.9 32.4 0.2 57.2 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.3 46.3 49.9 59.2 45.2 45.6 57.3 54.9 56.8 51.4 47.8 64.3 44.3 195.2 3.2 12.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 4.4 28.6 0.0 0.0 9.9 0.0 0.0 5.0 1.4 0.0 1.9 0.6 0.0 2.7 78.1 32.0 0.0 0.0 0.0 0.6 156.9 113.0 0.0 2.8 2.5 22.1 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.0 3.6 2.2 0.0 0.0 0.0 131.6 0.0 0.0 0.0 0.0 6.2 1.2 45.8 0.0 0.0 LIN7A "LIN-7A, MALS-1, TIP-33, VELI1" ENSG00000111052 "Lin-7 homolog A, crumbs cell polarity complex component" O14910 12 80792520-80937934 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.9;retina: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 77.3;Early spermatids: 107.2;Excitatory neurons: 135.5;Inhibitory neurons: 93.1;Late spermatids: 76.9;Spermatocytes: 61.3" "Cancer enhanced" "Detected in many" "renal cancer: 8.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 18.8;eosinophil: 15.8;neutrophil: 29.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 29.8" "Cell line enhanced" "Detected in many" "ASC diff: 21.3;ASC TERT1: 31.4;HAP1: 25.2;HDLM-2: 29.6;HL-60: 29.1;NB-4: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071562 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071562: AB_2732181" "unprognostic (7.11e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-3)" "unprognostic (3.04e-2)" "unprognostic (8.24e-2)" "unprognostic (4.24e-2)" "unprognostic (1.46e-2)" "unprognostic (8.83e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "prognostic favorable (1.63e-11)" "unprognostic (5.01e-5)" "unprognostic (7.79e-2)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" 5.0 3.1 5.5 2.4 6.5 27.9 5.4 22.2 8.0 7.9 1.0 1.9 0.5 8.5 0.5 0.9 3.7 4.0 6.3 6.4 6.0 8.7 17.7 5.1 2.6 1.9 6.9 3.7 0.5 0.9 6.0 5.3 3.1 1.8 0.6 26.6 0.8 0.7 1.0 0.7 2.1 4.6 2.3 4.6 1.1 7.1 6.9 0.7 4.2 2.5 1.2 3.9 4.6 3.6 0.0 0.6 5.0 0.0 21.3 31.4 0.0 12.8 5.9 5.1 1.1 9.9 0.0 0.0 0.0 4.9 0.1 0.0 25.2 0.0 1.5 29.6 7.8 0.0 0.2 15.6 2.6 29.1 0.2 7.8 0.0 0.5 0.5 1.2 4.1 0.0 0.0 0.0 2.3 0.3 0.0 27.0 4.7 0.3 0.1 0.0 18.7 0.0 2.9 4.1 10.2 0.0 0.0 0.0 0.1 0.3 1.1 15.5 0.0 4.0 1.5 2.1 0.1 4.4 0.0 0.0 0.4 0.0 0.2 18.8 5.2 15.8 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 29.8 0.0 0.2 0.0 0.1 1.2 5.5 6.5 22.2 8.0 6.4 6.0 1.9 6.9 3.1 2.3 6.9 3.6 4.8 22.4 5.8 18.6 0.0 0.8 4.8 0.0 0.0 77.3 10.8 3.4 22.8 8.6 0.6 25.8 2.1 0.4 0.2 0.3 9.8 1.3 107.2 1.9 8.9 1.9 1.8 0.4 135.5 0.2 0.1 4.9 0.0 3.5 0.0 0.1 1.8 21.5 2.5 30.3 93.1 0.5 0.0 5.2 0.7 76.9 4.7 4.2 0.0 9.4 6.5 42.6 0.0 23.1 2.7 0.0 1.2 1.5 0.4 2.0 20.1 26.5 0.7 11.2 13.1 5.0 19.2 61.3 1.3 0.0 0.4 0.7 0.6 3.5 1.1 1.8 LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 398.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 515.0;Kupffer cells: 714.8;Macrophages: 303.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.3;intermediate monocyte: 355.1;myeloid DC: 123.6;non-classical monocyte: 198.5" "Group enriched" "Detected in all" 6 "dendritic cells: 123.6;monocytes: 355.1" "Cell line enhanced" "Detected in many" "A-431: 354.4;AN3-CA: 367.8;ASC TERT1: 450.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" NA NA 280000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" 76.0 46.3 43.5 66.7 65.2 39.8 47.8 64.1 74.4 54.0 39.0 67.7 167.6 38.8 21.7 28.6 37.8 83.5 24.2 43.5 53.1 44.9 218.9 169.5 159.3 74.7 55.5 32.7 21.4 68.9 12.7 79.1 82.2 30.7 72.0 12.6 22.5 33.8 11.8 18.7 227.5 47.7 65.4 398.4 34.3 13.4 57.0 44.5 31.6 22.5 45.5 58.4 19.3 115.5 354.4 49.4 30.7 367.8 343.5 450.8 10.0 171.4 194.8 65.5 121.5 18.6 176.6 63.9 34.0 264.4 73.7 338.7 13.8 92.8 53.6 86.1 34.7 25.1 19.1 81.5 87.6 48.8 48.9 190.4 69.2 72.9 40.6 88.2 14.9 45.4 0.3 108.5 58.3 28.2 45.7 34.6 22.7 62.4 60.0 26.4 39.0 60.5 69.2 50.9 10.5 21.8 41.4 49.9 133.9 20.4 64.4 65.8 26.2 58.8 15.5 132.1 44.6 60.0 65.7 25.8 71.4 112.9 82.1 4.2 167.3 16.9 40.0 355.1 40.6 31.9 35.8 38.8 123.6 33.4 36.7 40.4 7.1 29.8 198.5 25.0 38.2 159.6 43.5 65.2 64.1 74.4 43.5 53.1 74.7 55.5 82.2 65.4 57.0 115.5 75.5 41.7 33.8 11.1 35.9 17.7 30.3 58.1 25.6 5.4 16.1 14.1 9.6 45.8 31.9 33.1 0.0 34.8 31.4 2.8 21.5 35.1 6.8 11.4 20.4 56.7 21.8 27.4 34.4 36.2 32.9 34.6 21.4 15.5 28.5 10.8 54.7 66.7 515.0 16.8 15.1 8.9 40.7 714.8 69.0 2.7 11.5 303.1 48.0 30.0 71.7 33.1 29.9 15.1 143.0 19.3 12.0 21.8 15.4 11.3 161.0 14.0 28.8 2.2 6.6 19.7 21.0 5.1 13.8 31.9 12.5 20.0 33.1 17.6 9.1 24.0 LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401514-42427388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 834.5;breast: 524.7" "Cell type enhanced" "Detected in many" "Adipocytes: 76.1;Early spermatids: 127.8;Late spermatids: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "ASC diff: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006567, CAB017700" Enhanced Supported Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017700: AB_2135504, HPA006567: AB_2667618" "unprognostic (4.24e-2)" "unprognostic (2.46e-2)" "unprognostic (8.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-3)" "unprognostic (5.68e-2)" "unprognostic (2.84e-1)" "unprognostic (3.11e-1)" "unprognostic (9.44e-2)" "prognostic favorable (1.15e-4)" "unprognostic (1.52e-1)" "unprognostic (3.63e-10)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.76e-2)" "unprognostic (2.34e-3)" 834.5 45.1 22.7 7.7 71.7 5.0 524.7 77.2 41.5 5.1 0.6 10.9 5.3 6.4 1.2 8.6 5.8 3.7 32.5 23.8 42.6 7.7 1.5 3.7 7.3 100.3 73.9 4.9 6.2 4.7 6.9 2.9 90.0 7.1 1.4 2.0 17.2 2.6 19.7 23.6 24.4 2.6 44.0 14.4 8.5 68.6 57.1 6.9 9.6 23.3 3.7 14.2 7.7 116.9 12.7 9.6 6.0 2.3 136.8 1.3 0.1 5.8 3.1 9.2 8.5 2.3 4.6 20.6 6.3 1.8 4.5 5.6 3.7 11.5 1.0 4.0 6.1 5.8 5.3 0.2 2.7 0.1 13.9 1.2 10.7 1.5 2.1 1.3 2.6 8.5 2.7 12.8 1.2 0.1 14.8 0.5 0.8 9.7 2.7 12.2 1.1 6.9 2.6 13.1 8.5 8.8 5.1 5.7 5.6 0.3 1.5 7.5 4.7 2.5 7.8 1.1 5.3 9.7 8.5 15.6 6.3 0.7 8.7 11.0 8.6 3.8 2.5 4.7 2.3 3.4 3.2 3.7 3.6 4.5 2.8 2.5 1.5 3.6 2.7 2.9 3.0 3.1 22.7 71.7 77.2 41.5 23.8 42.6 100.3 73.9 90.0 44.0 57.1 116.9 76.1 0.0 3.3 4.2 8.1 4.1 12.1 2.4 4.6 11.0 4.8 2.9 2.5 0.0 2.0 1.8 10.4 0.1 4.8 1.3 1.9 8.0 127.8 0.9 3.4 10.2 0.0 5.3 4.6 2.7 0.1 2.0 3.6 1.5 0.0 6.6 17.9 0.0 0.6 8.4 6.7 2.0 6.1 2.2 2.4 236.5 3.1 0.8 5.4 4.7 0.9 4.0 6.2 6.0 37.9 1.8 0.7 1.5 3.0 6.7 18.4 1.5 0.8 13.9 0.0 7.2 2.1 39.4 13.1 2.5 2.4 0.0 5.1 5.2 2.9 10.7 LMCD1 ENSG00000071282 "LIM and cysteine rich domains 1" Q9NZU5 3 8501807-8574668 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 573.4" "Cell type enhanced" "Detected in many" "Adipocytes: 287.6;Ductal cells: 122.0;Endothelial cells: 161.9;Pancreatic endocrine cells: 114.1;Smooth muscle cells: 112.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "T-reg: 20.5" "Lineage enriched" "Detected in many" 6 "T-cells: 20.5" "Cell line enhanced" "Detected in many" "HHSteC: 88.9;HSkMC: 124.9;hTEC/SVTERT24-B: 93.8;U-2197: 83.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024059 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" No No 6600 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane, Cell Junctions" "HPA024059: AB_1852950" "unprognostic (2.46e-1)" "unprognostic (1.79e-1)" "unprognostic (5.13e-3)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (2.96e-1)" "unprognostic (8.21e-3)" "unprognostic (4.29e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (8.66e-5)" "unprognostic (3.80e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-3)" "unprognostic (3.68e-3)" 131.4 14.3 9.5 45.6 9.5 0.1 97.5 13.5 10.8 27.2 38.8 18.1 9.0 90.3 18.4 36.1 57.8 67.2 90.6 14.0 9.7 33.0 9.7 131.7 17.3 14.0 11.0 65.8 37.7 30.0 8.7 54.5 12.1 34.8 7.0 15.2 42.2 16.8 573.4 28.8 20.1 63.3 13.2 55.6 46.4 11.3 12.6 4.7 18.5 260.9 10.2 110.6 31.5 14.8 9.4 52.0 8.6 6.6 62.0 34.6 8.9 37.9 19.4 20.5 50.0 38.8 11.5 0.0 4.2 44.2 8.8 0.8 4.9 9.9 8.4 16.0 3.6 11.6 3.5 7.6 88.9 0.0 1.1 124.9 0.2 93.8 0.7 11.9 10.1 0.0 0.0 0.0 26.8 6.7 0.0 0.1 16.8 12.0 2.3 0.2 28.2 0.1 19.1 3.6 0.3 21.3 6.4 31.1 20.6 23.9 40.7 0.1 5.0 20.4 40.3 83.0 25.9 5.1 6.2 2.6 4.1 2.9 27.0 0.0 0.0 0.0 0.0 0.4 0.1 2.0 2.9 0.6 3.3 0.3 0.0 0.1 0.0 0.0 0.0 1.0 20.5 0.3 9.5 9.5 13.5 10.8 14.0 9.7 14.0 11.0 12.1 13.2 12.6 14.8 287.6 9.6 10.7 2.0 2.1 31.6 42.1 7.4 9.6 13.0 20.4 17.0 14.7 14.3 13.5 5.5 10.4 3.9 1.7 1.4 3.9 122.0 1.1 9.6 77.7 161.9 12.1 0.0 0.8 48.5 4.2 64.5 7.1 4.8 10.2 44.2 30.7 12.6 3.4 97.6 1.2 2.4 4.1 0.8 47.0 2.3 11.5 3.2 53.4 29.0 9.0 38.9 1.0 4.0 8.7 114.1 0.9 32.4 8.0 8.4 0.3 45.5 12.0 8.0 0.0 57.0 112.9 6.4 9.1 29.0 27.1 4.4 5.3 21.5 4.7 7.5 LMLN2 ENSG00000283654 "Leishmanolysin like peptidase 2" A0A1B0GTW7 14 23099062-23104989 "Enzymes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "HSkMC: 2.5" "Not detected" "Not detected" NA NA "Cluster 34: Mesenchymal cell lines - ECM organization" 0.1 0.1 0.1 0.1 0.4 0.2 0.1 0.2 0.3 0.0 0.5 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.3 0.3 0.1 0.0 0.0 0.3 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.3 0.1 0.2 0.3 0.3 0.3 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LMO3 "DAT1, RBTNL2, Rhom-3" ENSG00000048540 "LIM domain only 3" Q8TAP4 12 16548372-16610594 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 93.7;intestine: 85.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Alveolar cells type 2: 210.2;Astrocytes: 293.8;Excitatory neurons: 226.2;Oligodendrocyte precursor cells: 112.6" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 32.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "ASC diff: 189.3;LHCN-M2: 91.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.67e-2)" "unprognostic (2.84e-1)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.10e-7)" "unprognostic (3.62e-2)" "unprognostic (5.44e-2)" "unprognostic (6.56e-3)" "unprognostic (4.91e-2)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (1.39e-5)" "unprognostic (4.41e-2)" "unprognostic (1.61e-1)" "unprognostic (2.13e-3)" "unprognostic (4.83e-2)" 27.1 8.0 72.8 2.3 89.5 0.0 13.4 35.0 93.7 38.2 25.9 85.6 1.0 18.4 2.7 2.6 7.3 5.2 6.5 85.4 43.5 3.0 0.4 33.8 0.2 42.4 61.9 8.6 39.3 0.7 20.3 1.1 48.2 13.1 9.7 2.7 3.2 28.6 1.6 1.9 14.0 11.3 40.8 0.5 7.1 0.9 67.1 15.3 50.6 1.7 0.0 54.9 18.5 59.2 0.0 0.0 0.2 0.1 189.3 7.4 0.1 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.8 0.1 0.0 0.2 0.0 0.0 0.8 0.6 2.5 0.0 0.0 4.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 91.9 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.1 3.6 1.3 14.3 0.0 0.0 0.0 0.2 0.8 0.0 0.7 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.8 89.5 35.0 93.7 85.4 43.5 42.4 61.9 48.2 40.8 67.1 59.2 8.3 173.1 210.2 293.8 0.1 0.3 0.2 5.8 0.0 0.3 2.8 1.4 1.1 0.0 62.8 53.3 18.8 0.2 0.1 0.0 3.9 0.0 5.7 1.8 0.4 0.3 0.0 0.0 226.2 3.6 0.0 23.5 0.0 0.1 5.1 2.5 0.0 0.0 0.2 0.0 46.8 0.0 8.2 0.0 0.5 0.8 0.9 0.7 3.6 18.7 0.0 0.8 0.0 112.6 7.0 0.5 0.0 0.4 0.1 0.2 0.0 0.1 63.7 0.6 0.0 6.3 10.4 1.7 0.8 0.2 0.1 0.3 0.6 0.0 0.0 0.2 LMOD2 ENSG00000170807 "Leiomodin 2" Q6P5Q4 7 123655866-123664290 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "heart muscle: 778.4;skeletal muscle: 933.7;tongue: 793.6" "Cell type enriched" "Detected in some" 26 "Cardiomyocytes: 1432.4" "Group enriched" "Detected in some" 20 "head and neck cancer: 3.5;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA046370, HPA051039" Enhanced Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "HPA046370: , HPA051039: AB_2681321" "unprognostic (2.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (5.50e-1)" "unprognostic (5.69e-2)" "unprognostic (6.98e-2)" "unprognostic (2.13e-2)" "unprognostic (1.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.51e-1)" "unprognostic (1.82e-3)" 0.2 0.1 0.0 0.0 0.0 0.6 0.5 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 21.2 0.0 0.1 778.4 0.2 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.8 0.0 10.2 0.0 0.1 10.0 0.0 933.7 0.4 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.2 793.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1432.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.5 0.4 9.4 0.0 0.0 0.1 0.0 0.1 27.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.9 7.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LMOD3 ENSG00000163380 "Leiomodin 3" Q0VAK6 3 69106065-69123032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 111.2;skeletal muscle: 459.8;tongue: 228.2" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 278.1" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 1.6" "Region enriched" "Detected in single" 4 "midbrain: 2.3" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 4 "HSkMC: 2.9" "Not detected" "Not detected" HPA036034 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA036034: AB_10673494" "unprognostic (1.66e-1)" "unprognostic (2.65e-1)" "unprognostic (1.04e-2)" "unprognostic (1.32e-2)" "unprognostic (1.93e-1)" "unprognostic (2.50e-3)" "unprognostic (1.96e-2)" "unprognostic (2.77e-2)" "unprognostic (1.39e-1)" "unprognostic (6.57e-2)" "unprognostic (3.63e-1)" "unprognostic (4.33e-1)" "unprognostic (2.98e-4)" "unprognostic (3.67e-3)" "unprognostic (1.29e-1)" "unprognostic (8.86e-2)" "unprognostic (2.96e-1)" 0.2 0.1 0.3 0.2 0.4 0.2 0.1 0.3 0.5 0.1 0.2 0.1 0.2 0.0 0.2 6.4 0.0 0.3 111.2 0.3 0.3 0.1 0.1 0.5 0.2 0.3 2.3 0.0 0.4 0.0 0.9 0.5 0.3 3.8 0.1 1.3 9.0 0.4 459.8 0.2 0.2 0.1 0.1 0.7 0.4 0.1 0.2 0.1 0.1 228.2 0.0 0.8 0.1 0.5 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.3 2.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.2 1.6 0.2 0.4 0.2 0.2 0.2 0.3 0.4 0.3 0.1 0.3 0.3 0.4 0.4 0.2 0.4 0.2 0.4 0.1 0.3 0.4 0.3 0.5 0.3 0.3 0.3 2.3 0.3 0.1 0.2 0.5 0.5 0.0 0.0 0.3 6.2 2.3 1.5 2.1 0.0 5.0 2.4 1.8 278.1 5.7 1.3 0.0 39.6 0.8 10.0 2.4 0.0 1.0 1.6 3.4 1.2 2.4 0.0 0.0 0.1 0.0 2.1 8.2 0.0 10.0 17.8 0.5 0.7 1.2 0.7 6.7 2.0 1.9 6.1 2.2 28.1 0.5 0.3 2.2 12.4 0.0 3.9 1.0 13.4 0.0 0.3 1.1 0.2 1.2 0.9 2.6 6.1 0.4 0.3 18.1 0.0 33.1 3.4 0.6 0.1 0.8 1.4 0.4 8.2 0.9 1.1 2.5 LPAR1 "edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1" ENSG00000198121 "Lysophosphatidic acid receptor 1" Q92633 9 110873263-111038458 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 358.4;choroid plexus: 122.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 626.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.1;eosinophil: 19.0" "Group enriched" "Detected in many" 6 "granulocytes: 19.0;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 582.0;ASC TERT1: 337.0;BJ hTERT+: 426.7;HSkMC: 246.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050667 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles" "Plasma membrane" "HPA050667: " "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (4.79e-2)" "unprognostic (6.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.17e-2)" "unprognostic (2.10e-1)" "unprognostic (1.40e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (4.29e-3)" "unprognostic (2.12e-2)" "unprognostic (5.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" 30.5 13.3 251.0 18.8 315.0 0.2 25.9 208.8 318.6 57.7 122.2 24.5 13.9 17.0 17.1 15.2 15.8 14.1 24.1 199.5 201.3 9.6 2.6 16.3 17.6 299.6 277.5 12.1 6.6 2.2 5.0 38.8 249.2 21.0 18.3 0.8 16.7 23.6 6.6 20.1 18.3 20.5 224.0 14.8 11.8 6.9 266.2 6.8 16.5 17.5 17.2 27.6 31.7 358.4 11.7 22.2 30.4 0.1 582.0 337.0 0.0 151.6 426.7 104.1 46.8 3.0 1.8 0.0 0.1 157.7 18.6 45.5 0.4 118.5 85.0 0.0 4.1 0.0 1.1 0.0 157.1 0.1 0.2 246.6 6.8 51.4 96.9 62.3 1.8 0.2 0.0 0.2 80.8 0.1 0.0 0.1 5.9 0.0 121.6 0.1 22.4 0.0 23.5 20.6 0.9 7.2 3.1 0.0 0.0 6.2 10.4 0.5 0.1 48.9 1.3 35.3 0.1 1.5 0.0 0.0 7.4 0.0 54.9 1.5 9.1 19.0 0.0 3.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 1.9 2.1 1.3 0.2 0.0 2.1 251.0 315.0 208.8 318.6 199.5 201.3 299.6 277.5 249.2 224.0 266.2 358.4 1.9 0.0 1.1 6.2 0.2 13.0 15.5 8.5 4.0 0.0 3.4 6.0 1.4 1.5 9.1 0.0 0.0 0.5 0.3 6.6 1.9 1.8 1.4 3.6 40.4 1.9 0.0 0.0 1.0 2.9 0.4 61.4 6.1 8.7 0.0 0.0 2.5 0.0 3.3 0.0 15.6 3.7 4.1 4.1 15.1 2.7 38.8 3.6 14.2 141.5 12.0 1.0 1.0 1.0 626.8 2.0 2.9 70.7 0.7 12.7 4.5 0.2 3.0 0.2 0.0 13.3 6.3 0.3 2.4 15.2 9.2 0.8 1.2 0.2 4.2 6.7 LPCAT3 "C3F, MBOAT5, nessy, OACT5" ENSG00000111684 "Lysophosphatidylcholine acyltransferase 3" Q6P1A2 12 6976185-7018477 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 103.5;Proximal enterocytes: 121.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 156.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.74e-1)" "unprognostic (3.33e-2)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (6.72e-2)" "unprognostic (3.86e-1)" "unprognostic (2.40e-2)" "unprognostic (6.90e-2)" "unprognostic (1.88e-1)" "unprognostic (5.00e-3)" "unprognostic (2.06e-1)" "unprognostic (2.58e-2)" "prognostic favorable (4.89e-5)" "unprognostic (1.13e-1)" "unprognostic (2.21e-1)" "unprognostic (6.49e-3)" "unprognostic (1.23e-1)" 36.6 52.1 8.4 21.6 9.3 28.4 36.3 11.1 9.5 20.3 10.3 51.4 123.0 18.8 21.5 32.0 21.2 18.6 37.4 8.3 9.0 44.4 109.2 46.0 17.0 11.0 9.7 17.7 50.8 19.6 15.2 38.0 9.2 35.9 47.9 4.0 37.3 16.3 45.6 34.0 99.7 21.7 9.2 20.1 58.7 11.2 9.9 21.5 27.7 57.5 21.2 35.3 21.7 9.3 20.2 34.0 15.8 44.3 109.4 51.2 32.9 11.8 49.5 31.7 53.4 78.6 103.9 21.9 6.5 19.1 65.7 50.8 19.2 43.0 24.3 52.7 21.3 44.7 28.2 71.5 23.6 23.3 45.8 81.2 24.7 30.2 15.1 20.1 30.0 33.0 24.4 15.4 20.9 30.0 29.1 28.7 53.1 73.1 20.2 29.9 21.5 22.4 38.7 156.0 13.6 12.5 68.5 107.3 7.9 49.5 10.9 31.4 12.0 19.2 27.8 34.1 8.3 19.1 14.5 30.9 24.0 23.5 17.0 44.4 55.7 91.0 21.5 80.5 25.4 12.3 22.3 24.8 37.2 12.3 20.1 21.3 53.7 32.3 98.7 21.1 29.7 38.3 8.4 9.3 11.1 9.5 8.3 9.0 11.0 9.7 9.2 9.2 9.9 9.3 17.9 70.5 38.5 15.7 13.1 23.6 39.4 35.8 36.5 5.2 19.8 13.8 0.6 12.8 30.3 20.2 0.0 103.5 11.6 47.0 11.7 29.9 2.5 18.8 21.4 13.1 43.2 57.7 20.7 33.0 51.7 14.3 49.5 26.6 14.0 10.6 15.0 62.9 41.6 11.8 16.7 26.8 26.4 21.9 9.6 1.7 18.3 15.2 7.2 6.5 15.8 12.2 15.5 25.6 22.4 18.1 27.1 6.4 17.5 24.7 121.9 37.2 16.4 4.0 19.7 6.0 18.2 24.3 35.3 17.7 22.3 66.4 18.9 17.0 41.2 25.9 LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2916994-3013144 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 165.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 154.4;Granulosa cells: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "granulocytes: 23.4;NK-cells: 12.5;T-cells: 12.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: AB_2673519" "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favorable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" 9.7 9.3 17.9 21.2 19.9 19.8 9.8 14.6 17.4 9.7 16.6 13.9 62.8 9.8 6.7 10.0 9.5 25.7 7.2 16.1 24.2 26.4 165.8 21.2 24.3 22.7 22.0 13.2 16.4 13.5 10.9 15.7 24.2 9.0 12.5 10.7 7.4 8.0 2.7 3.6 39.9 9.6 15.6 20.3 28.1 22.0 28.8 18.9 12.1 3.0 19.2 9.9 6.0 14.3 8.7 12.0 17.1 6.6 31.7 27.4 10.5 17.4 22.8 18.9 16.9 16.7 7.1 5.4 10.8 30.2 30.2 0.2 13.8 6.3 13.2 11.2 2.7 13.3 10.0 19.4 27.2 11.2 17.0 27.4 4.6 18.5 17.2 28.2 23.4 14.8 12.8 3.5 28.2 7.2 15.0 12.0 5.7 13.7 13.1 26.7 14.0 23.2 17.6 20.0 14.4 10.2 18.4 9.1 6.8 10.7 0.0 18.0 31.2 25.3 28.7 31.7 14.6 5.0 7.9 12.3 22.1 12.2 8.1 8.7 2.4 7.8 11.8 1.5 12.1 1.0 9.2 7.2 1.0 1.7 9.1 6.3 23.4 12.5 0.8 1.5 9.2 3.2 17.9 19.9 14.6 17.4 16.1 24.2 22.7 22.0 24.2 15.6 28.8 14.3 17.7 67.3 44.0 55.2 20.4 5.6 9.8 8.5 5.7 35.7 12.1 11.2 11.2 154.4 23.9 38.6 14.6 25.2 41.9 45.3 17.6 11.8 3.3 48.2 33.3 18.9 14.9 138.1 26.3 19.0 11.3 25.4 103.0 64.4 12.6 323.0 19.2 131.1 23.1 116.1 65.6 36.8 16.2 26.8 8.9 11.0 22.7 31.1 8.8 79.6 31.2 16.7 59.8 37.7 21.0 22.2 21.6 31.2 16.1 21.2 92.4 54.9 17.1 16.7 6.6 16.6 20.1 26.5 73.0 0.6 2.0 49.5 58.9 20.3 14.0 14.1 LRP1 "A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A" ENSG00000123384 "LDL receptor related protein 1" Q07954 12 57128483-57213361 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Endocytosis "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 109.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 273.4;Hepatocytes: 188.4;Leydig cells: 233.3;Peritubular cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "classical monocyte: 4.3;intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 21 "dendritic cells: 1.6;monocytes: 4.3" "Cell line enhanced" "Detected in many" "ASC diff: 484.8;ASC TERT1: 488.4;fHDF/TERT166: 222.2;HSkMC: 318.5;hTERT-RPE1: 248.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004182, CAB018621, HPA022903" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 180000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB018621: AB_627893, HPA004182: AB_2667163, HPA022903: AB_10602426" "unprognostic (1.65e-1)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (5.00e-2)" "unprognostic (4.33e-2)" "unprognostic (3.98e-1)" "unprognostic (8.68e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-3)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.29e-5)" 109.2 14.1 21.3 29.0 36.3 8.2 40.0 30.2 19.7 32.3 8.0 24.1 23.2 36.9 6.2 19.3 30.3 31.5 35.5 16.7 21.9 5.7 35.0 34.0 4.9 46.0 31.5 71.0 10.7 7.8 10.2 39.8 27.9 13.8 11.2 9.9 20.3 20.2 13.0 20.4 18.4 28.9 27.1 13.6 15.1 7.3 48.9 5.6 17.6 23.5 2.7 25.5 29.3 27.6 7.7 14.5 30.4 24.2 484.8 488.4 91.2 85.3 109.0 27.5 26.7 26.9 12.4 0.4 10.4 222.2 6.0 33.6 5.3 8.7 9.7 0.7 1.3 0.4 17.9 56.4 66.5 0.5 14.6 318.5 3.1 61.8 7.2 248.7 1.7 1.1 0.4 1.3 87.2 1.7 0.2 0.4 34.8 11.0 8.8 3.2 171.0 1.6 1.9 2.2 1.4 16.4 19.0 0.6 13.2 42.0 2.9 1.2 1.2 96.0 35.0 53.9 5.2 1.1 0.1 0.2 167.4 0.1 18.7 0.0 4.3 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 1.6 21.3 36.3 30.2 19.7 16.7 21.9 46.0 31.5 27.9 27.1 48.9 27.6 24.6 12.8 8.4 113.6 3.2 24.0 11.9 28.7 19.9 29.2 4.9 19.3 14.8 15.7 14.7 1.8 0.0 87.5 1.1 81.7 0.0 7.4 1.9 9.7 111.4 13.0 4.2 0.8 39.3 1.8 53.0 273.4 49.5 4.2 6.3 36.9 11.0 188.4 73.8 8.4 41.6 14.1 6.1 145.3 28.6 8.4 233.3 102.9 28.4 89.9 48.8 154.7 1.0 173.4 6.6 14.7 27.2 184.3 4.4 5.5 86.0 2.1 15.1 7.3 39.5 129.7 77.0 1.6 2.4 35.4 16.1 125.9 4.2 11.4 25.0 12.3 LRRN4CL ENSG00000177363 "LRRN4 C-terminal like" Q8ND94 11 62686406-62689530 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 62.1;Leydig cells: 27.1;Melanocytes: 33.8;Peritubular cells: 17.3;Skeletal myocytes: 33.0" "Cancer enriched" "Detected in many" 5 "melanoma: 26.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 7.7;ASC TERT1: 25.3;HHSteC: 19.8;HSkMC: 10.6;LHCN-M2: 13.4" "Low region specificity" "Detected in many" HPA050317 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA050317: AB_2681084" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (2.84e-1)" "unprognostic (9.95e-3)" "unprognostic (2.61e-2)" "unprognostic (4.03e-3)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (3.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-7)" "unprognostic (2.73e-2)" "unprognostic (6.12e-2)" "unprognostic (4.53e-3)" "unprognostic (1.86e-2)" 23.3 6.6 0.4 2.5 0.4 0.5 16.0 1.5 1.3 22.4 2.6 15.1 1.8 29.7 3.7 4.5 18.2 3.6 7.2 0.6 0.6 1.0 0.1 3.5 0.5 0.5 0.3 21.0 1.1 0.3 1.7 0.7 0.4 6.1 2.1 0.4 5.5 5.8 4.8 10.6 7.2 9.1 0.2 0.2 8.2 1.5 0.5 0.4 4.2 5.6 0.3 9.7 16.1 0.7 0.0 0.1 0.2 0.3 7.7 25.3 0.3 2.8 4.0 0.3 1.4 0.2 0.1 0.2 0.3 4.6 0.1 0.3 0.1 0.0 0.4 0.2 0.2 0.5 0.2 0.2 19.8 0.2 0.2 10.6 0.1 0.6 0.0 0.2 0.1 0.4 0.3 0.1 13.4 0.1 0.3 0.6 0.6 0.1 0.1 0.1 1.7 0.3 0.0 0.2 0.8 0.3 0.4 0.3 0.8 0.1 0.2 0.3 0.3 2.4 0.2 2.7 0.1 0.2 0.2 0.3 1.5 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.0 0.4 0.4 1.5 1.3 0.6 0.6 0.5 0.3 0.4 0.2 0.5 0.7 4.0 0.0 1.8 0.0 0.1 6.6 2.1 0.0 0.0 2.1 0.5 0.8 1.5 0.0 0.6 0.0 2.1 0.1 0.2 0.0 0.0 0.0 1.0 0.5 11.0 3.7 1.2 0.0 0.1 0.0 0.2 62.1 0.5 0.4 1.3 0.2 1.4 0.1 0.4 1.7 0.3 0.3 0.0 0.6 8.3 0.5 27.1 1.1 33.8 1.9 0.1 0.2 1.0 0.0 0.1 0.0 0.1 17.3 0.4 1.4 0.1 0.3 0.0 1.0 0.0 33.0 2.8 0.4 0.3 0.5 7.0 0.1 1.1 1.2 0.1 1.3 LTBP1 ENSG00000049323 "Latent transforming growth factor beta binding protein 1" Q14766 2 32946953-33399509 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 161.4" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Fibroblasts: 116.1;Leydig cells: 90.4;Peritubular cells: 161.0;Skeletal myocytes: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 569.4;HSkMC: 185.3;HUVEC TERT2: 194.5;U-2197: 181.1;U-87 MG: 255.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB025428 Approved "Secreted to extracellular matrix" NA NA 96000000 "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025428: " "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (5.29e-2)" "unprognostic (6.23e-2)" "unprognostic (3.11e-3)" "unprognostic (1.83e-1)" "unprognostic (1.06e-3)" "unprognostic (5.67e-2)" "unprognostic (7.48e-2)" "unprognostic (1.14e-1)" "unprognostic (9.96e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.79e-6)" "unprognostic (4.61e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.62e-4)" 22.9 13.1 7.8 22.1 9.4 11.5 14.5 7.1 7.5 161.4 10.5 27.2 10.2 58.9 37.8 21.2 37.0 73.0 89.0 8.8 9.1 38.6 18.6 27.5 6.9 12.1 10.6 30.2 7.9 2.4 9.0 73.2 9.2 46.9 16.5 0.7 14.6 73.6 15.7 10.8 15.0 96.7 9.1 8.3 32.8 17.9 8.8 8.2 6.5 28.4 18.7 53.9 28.3 13.4 0.3 12.5 31.3 0.3 26.1 569.4 13.5 46.5 95.7 6.4 9.3 25.3 4.6 41.3 1.0 6.0 8.8 2.4 0.7 1.5 22.0 0.6 15.3 135.6 15.0 4.1 118.6 0.5 15.7 185.3 4.4 141.2 6.9 61.8 194.5 6.3 8.7 0.3 51.1 19.9 5.5 0.2 22.4 1.0 39.2 4.7 65.8 0.6 0.4 22.4 6.3 3.4 9.5 72.1 0.8 49.1 27.9 0.4 126.4 6.4 26.2 181.1 37.6 74.8 80.0 58.8 255.9 5.2 10.8 3.1 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 5.3 7.8 9.4 7.1 7.5 8.8 9.1 12.1 10.6 9.2 9.1 8.8 13.4 33.6 0.0 0.6 108.4 0.4 13.5 5.6 13.0 10.2 0.0 6.9 6.6 80.9 4.3 3.6 1.8 0.0 45.2 0.3 12.9 0.0 9.6 6.3 7.3 18.3 28.1 1.2 30.3 30.4 6.5 23.4 116.1 10.2 10.5 0.0 11.8 20.3 11.0 7.6 0.0 54.3 2.8 2.0 0.3 18.1 7.1 90.4 12.0 19.6 39.4 0.4 0.2 0.0 70.4 52.4 19.1 3.3 161.0 1.3 19.1 0.7 0.3 6.3 0.3 59.2 85.8 67.9 0.7 11.9 6.9 9.8 43.5 2.0 2.6 4.1 33.4 MAGEH1 APR1 ENSG00000187601 "MAGE family member H1" Q9H213 X 55452127-55453566 "Predicted membrane proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "epididymis: 515.9" "Cell type enhanced" "Detected in many" "Peritubular cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011324, HPA011971" Uncertain Supported "Nucleoli,Nucleoli rim" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoli, Nucleoli rim" "HPA011324: AB_1853499, HPA011971: " "unprognostic (2.50e-1)" "unprognostic (3.01e-1)" "unprognostic (4.07e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (3.95e-2)" "unprognostic (8.50e-2)" "unprognostic (1.13e-2)" "unprognostic (9.93e-3)" "unprognostic (1.47e-1)" "unprognostic (3.20e-3)" "prognostic favorable (2.60e-4)" "unprognostic (6.37e-2)" "unprognostic (1.81e-2)" "unprognostic (1.29e-3)" "unprognostic (1.90e-1)" "unprognostic (3.95e-2)" "unprognostic (2.52e-1)" 20.2 29.9 46.8 17.6 48.2 5.1 18.4 40.9 59.3 29.6 59.4 21.0 10.2 30.9 515.9 10.0 45.3 18.1 24.1 47.1 60.0 25.5 19.6 23.5 22.7 41.9 47.7 36.3 28.1 25.5 54.1 20.9 45.7 48.8 11.5 22.0 18.6 44.3 12.9 11.3 17.1 27.3 45.5 20.4 25.3 33.8 50.3 32.0 28.6 16.9 17.0 17.9 16.7 48.8 0.1 5.7 32.6 0.0 51.5 31.0 0.4 36.0 32.9 9.7 26.0 0.1 7.4 0.0 48.2 36.4 18.4 4.9 12.5 13.5 15.2 42.5 2.0 11.4 0.0 4.6 17.0 0.6 14.1 25.8 1.2 5.6 4.1 9.1 15.0 12.0 6.5 43.8 10.8 22.0 30.8 9.8 9.3 0.0 6.8 19.1 4.1 24.0 17.9 0.0 0.2 24.5 0.0 9.5 15.5 24.4 4.7 8.5 17.7 13.3 15.4 8.2 1.9 25.9 35.1 4.9 24.8 15.8 17.2 14.0 9.0 20.5 21.5 14.3 19.4 18.9 35.4 24.6 13.7 17.9 48.2 30.5 1.2 18.9 18.5 28.5 52.1 19.0 46.8 48.2 40.9 59.3 47.1 60.0 41.9 47.7 45.7 45.5 50.3 48.8 24.9 6.4 14.4 4.9 18.3 8.0 7.8 20.0 5.2 36.7 8.0 14.1 10.4 18.6 12.5 12.9 10.4 2.8 15.7 1.9 13.7 32.2 1.6 2.8 33.5 29.0 15.8 3.0 14.2 10.7 2.0 42.9 3.1 1.9 12.7 11.1 32.9 14.0 15.0 37.0 17.5 8.4 4.1 3.8 11.2 4.0 47.2 6.2 21.4 6.5 9.3 56.8 23.7 18.6 28.4 4.7 8.8 63.9 39.8 13.7 0.8 20.1 6.7 19.6 26.3 44.5 35.0 1.4 2.7 3.3 6.3 1.6 19.9 19.7 4.6 4.8 MAN1A1 ENSG00000111885 "Mannosidase alpha class 1A member 1" P33908 6 119177205-119349761 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 154.6" "Cell type enhanced" "Detected in many" "Early spermatids: 232.5;Excitatory neurons: 165.0;Hepatocytes: 270.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 273.1;Hep G2: 204.0;Karpas-707: 219.6;U-266/70: 294.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037058, HPA053198, HPA063561" Uncertain Supported "Golgi apparatus" NA NA 460000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "CAB037058: AB_477183, HPA053198: AB_2682078, HPA063561: AB_2685042" "unprognostic (1.50e-1)" "unprognostic (7.36e-3)" "unprognostic (4.83e-2)" "unprognostic (2.21e-2)" "unprognostic (2.95e-2)" "unprognostic (2.19e-1)" "unprognostic (3.33e-3)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" "unprognostic (5.11e-2)" "unprognostic (1.68e-3)" "unprognostic (4.62e-1)" "unprognostic (2.37e-2)" "unprognostic (3.49e-2)" "unprognostic (2.25e-1)" "unprognostic (6.89e-2)" "unprognostic (3.40e-1)" 102.2 48.5 4.2 32.8 12.3 28.9 34.3 1.2 8.9 25.9 5.1 36.1 52.7 23.8 8.8 22.7 16.0 47.1 15.3 8.0 4.6 66.6 154.6 35.8 34.8 2.9 5.0 20.1 32.7 25.8 4.6 79.4 2.5 18.1 29.3 6.2 42.7 15.0 7.6 14.3 69.8 27.2 3.3 36.5 25.9 7.0 8.4 18.9 22.6 31.0 25.9 56.0 17.1 5.9 0.2 0.0 3.4 0.0 273.1 119.9 6.6 6.9 41.4 5.1 12.5 19.8 2.6 43.2 0.3 26.5 65.7 0.4 7.6 0.1 6.4 64.5 19.4 36.3 3.9 204.0 27.2 0.1 17.7 82.4 5.3 41.6 25.3 22.1 3.4 12.6 128.1 219.6 39.7 6.1 1.7 0.3 2.3 20.0 10.0 12.1 4.2 66.6 13.4 35.4 14.1 21.0 0.1 0.6 0.0 8.3 10.4 4.8 24.8 16.9 15.4 32.0 15.8 294.5 44.6 84.8 50.2 0.7 10.4 4.3 0.3 1.1 1.1 0.5 2.3 0.7 0.6 0.6 0.3 0.4 0.3 0.9 1.9 0.9 0.5 2.8 0.7 0.3 4.2 12.3 1.2 8.9 8.0 4.6 2.9 5.0 2.5 3.3 8.4 5.9 37.1 9.6 46.1 19.9 31.0 31.7 5.7 1.2 5.2 28.1 18.8 5.8 4.4 44.3 6.9 106.7 0.0 6.8 40.6 23.3 5.9 9.4 232.5 5.9 63.9 42.1 48.0 40.4 165.0 37.8 12.4 98.4 18.8 10.7 3.8 24.0 97.5 270.5 101.1 0.0 79.4 61.1 0.0 84.6 91.2 39.3 26.4 98.0 28.4 128.4 13.5 1.7 42.2 4.5 3.7 14.8 18.9 4.1 147.5 5.3 92.2 33.5 4.6 5.0 6.6 12.9 27.8 2.8 3.9 3.4 27.8 6.2 24.3 14.6 18.9 9.7 MAN1C1 HMIC ENSG00000117643 "Mannosidase alpha class 1C member 1" Q9NR34 1 25616791-25786206 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.2;Excitatory neurons: 72.8;Hepatic stellate cells: 63.9;Hepatocytes: 57.8;Inhibitory neurons: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.7" "Lineage enriched" "Detected in single" 5 "T-cells: 4.7" "Cell line enhanced" "Detected in many" "AF22: 30.5;HSkMC: 108.9;U-266/70: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048352 Uncertain Uncertain Nucleoplasm,Vesicles NA NA 1800000 "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Vesicles" "HPA048352: AB_2680368" "unprognostic (2.75e-1)" "unprognostic (5.45e-3)" "unprognostic (5.71e-3)" "unprognostic (2.05e-2)" "unprognostic (1.95e-1)" "unprognostic (8.90e-3)" "unprognostic (4.78e-2)" "prognostic favorable (7.55e-4)" "unprognostic (1.80e-1)" "unprognostic (5.70e-2)" "prognostic favorable (4.79e-4)" "unprognostic (2.51e-1)" "unprognostic (9.09e-3)" "unprognostic (3.18e-2)" "unprognostic (7.23e-2)" "unprognostic (7.44e-2)" "unprognostic (5.18e-2)" 12.5 11.6 13.3 9.4 15.2 2.2 6.2 16.6 16.1 19.6 27.3 10.0 4.5 14.5 7.5 7.0 9.7 18.6 10.1 15.9 16.9 25.4 29.6 9.2 12.4 45.1 23.2 17.3 3.6 24.0 17.1 21.1 26.1 17.6 4.6 11.0 5.7 17.9 4.6 8.1 6.1 19.9 29.4 19.3 7.3 4.2 16.4 10.5 26.0 5.5 9.4 12.3 9.1 37.8 0.1 0.4 30.5 6.4 22.4 17.2 8.6 0.4 5.8 1.4 0.4 0.6 0.2 0.1 0.3 2.3 3.9 0.4 3.0 0.3 0.6 9.8 1.3 0.6 0.5 0.1 2.6 5.2 12.0 108.9 0.5 0.7 0.0 0.4 0.1 1.2 0.1 1.3 0.0 1.6 0.0 5.8 7.8 0.1 0.2 0.6 18.9 0.6 0.2 0.7 17.7 0.6 0.7 4.7 1.5 5.5 2.4 3.6 0.1 0.0 1.6 20.1 0.7 31.7 0.1 0.1 4.6 10.7 1.5 0.3 0.9 0.4 0.3 0.6 0.5 0.2 2.1 0.9 0.3 0.5 4.7 2.7 0.6 0.4 0.8 0.2 0.5 0.7 13.3 15.2 16.6 16.1 15.9 16.9 45.1 23.2 26.1 29.4 16.4 37.8 5.8 3.2 3.2 18.3 2.0 6.6 2.9 3.6 5.2 23.5 1.1 1.5 7.0 4.3 7.3 22.0 54.2 10.6 1.6 0.5 9.8 1.0 0.3 0.4 8.1 8.4 3.0 2.7 72.8 3.8 0.9 23.3 1.1 0.6 2.5 0.3 63.9 57.8 24.8 21.9 65.8 0.1 16.2 19.0 4.3 2.1 27.1 6.8 1.8 39.4 3.3 17.8 3.1 25.1 21.7 1.4 0.3 22.2 2.2 2.0 0.0 23.3 2.2 4.4 6.6 17.0 7.1 0.2 2.9 1.0 5.3 42.7 6.9 0.7 0.2 1.9 MAN2B2 KIAA0935 ENSG00000013288 "Mannosidase alpha class 2B member 2" Q9Y2E5 4 6575189-6623362 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "Secreted to blood" NA NA 15000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "unprognostic (1.30e-1)" "unprognostic (3.32e-1)" "unprognostic (1.28e-1)" "prognostic favorable (7.59e-4)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (2.38e-2)" "unprognostic (2.72e-1)" "unprognostic (6.53e-2)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-3)" "unprognostic (2.18e-1)" 20.0 13.6 12.9 13.8 18.2 14.8 16.4 7.7 14.3 17.6 26.0 14.5 13.4 18.6 14.1 11.3 17.7 15.9 22.6 13.2 15.6 15.1 23.7 18.2 13.5 13.0 13.2 26.6 22.0 9.2 17.9 12.9 11.8 18.0 7.9 5.2 16.7 11.5 4.7 13.6 15.8 10.3 10.6 17.7 20.1 4.4 15.0 9.0 23.2 4.7 8.5 19.3 15.9 11.9 17.5 15.6 2.9 21.0 44.7 30.9 19.7 35.0 40.5 16.8 22.9 9.0 32.3 8.7 16.5 38.2 39.2 17.4 1.0 11.1 9.2 10.4 8.8 11.7 10.9 10.2 19.5 22.0 51.8 41.0 10.9 13.4 3.6 30.3 19.7 10.8 5.1 21.9 22.1 10.8 10.9 13.9 3.8 21.8 11.9 10.7 14.4 10.4 8.8 17.4 5.0 5.5 23.4 13.9 8.9 10.0 27.7 29.1 36.3 30.3 9.1 38.2 22.5 9.0 8.4 4.2 35.4 25.5 26.7 15.4 9.0 14.3 11.7 13.2 8.9 4.2 7.0 10.7 8.6 4.4 6.3 8.2 11.0 6.8 17.5 3.3 10.7 11.0 12.9 18.2 7.7 14.3 13.2 15.6 13.0 13.2 11.8 10.6 15.0 11.9 9.8 16.0 18.9 7.8 11.6 5.0 5.5 4.9 11.4 8.9 8.2 5.6 17.0 20.0 11.1 11.0 6.2 13.5 12.9 18.3 1.9 9.7 0.6 18.7 15.8 8.2 7.8 5.7 9.4 10.7 10.2 18.4 11.7 36.8 10.8 11.1 17.5 44.1 20.9 10.1 8.3 11.0 2.0 30.2 8.2 1.1 19.6 18.0 3.6 8.4 11.2 13.0 5.2 6.0 8.9 10.1 9.0 24.5 15.1 7.1 11.7 4.2 9.5 7.4 13.1 7.5 8.5 1.1 0.6 8.0 3.8 8.5 15.6 4.4 8.9 4.6 MANBA ENSG00000109323 "Mannosidase beta" O00462 4 102630770-102760994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 74.0;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.6" "Group enriched" "Detected in many" 5 "dendritic cells: 5.3;granulocytes: 16.6;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;hTCEpi: 13.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053478 Approved Supported Vesicles NA NA 15000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 57: B-cells - Immune response" Vesicles "HPA053478: AB_2682165" "unprognostic (2.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.80e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (7.78e-2)" "unprognostic (1.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (7.12e-2)" "unprognostic (4.81e-2)" "unprognostic (2.13e-1)" 7.1 12.4 1.9 1.5 2.4 7.0 6.4 4.7 2.2 6.5 2.2 6.7 1.6 6.1 0.2 3.8 6.3 1.3 6.6 1.1 2.1 4.8 4.7 10.5 2.1 3.8 2.9 8.8 8.3 3.0 5.0 3.7 4.7 4.3 1.1 2.7 8.9 2.0 3.0 4.5 8.5 2.4 3.0 12.0 9.1 1.6 3.5 1.2 7.1 0.1 2.0 8.1 5.8 3.7 2.9 1.4 0.6 1.6 15.5 12.1 0.9 1.1 6.9 1.8 4.1 1.7 1.0 3.6 1.4 2.7 3.9 1.0 3.0 2.2 1.1 2.2 0.7 3.0 1.1 0.7 2.7 2.8 8.2 3.7 13.7 7.6 3.4 8.9 3.0 1.2 3.6 2.0 3.4 1.4 2.0 2.3 1.3 1.9 1.1 1.9 1.6 0.6 3.4 2.3 1.4 0.5 1.4 1.9 1.5 5.4 4.5 1.8 0.2 2.0 1.3 9.3 1.2 1.3 5.8 0.5 3.1 1.5 1.6 4.0 6.8 16.6 0.4 6.1 0.7 1.7 0.0 0.7 5.3 2.1 0.4 0.6 6.1 1.8 9.1 1.2 0.5 3.1 1.9 2.4 4.7 2.2 1.1 2.1 3.8 2.9 4.7 3.0 3.5 3.7 6.4 32.1 35.6 24.5 45.4 5.9 8.4 13.2 12.0 6.2 11.6 8.1 14.6 14.3 13.5 9.2 6.2 42.3 14.3 5.1 1.9 8.1 2.8 6.9 6.9 8.1 1.8 19.7 36.4 2.7 7.3 13.8 25.5 12.8 34.8 5.5 10.4 17.7 43.6 6.7 66.5 10.5 2.0 58.5 29.6 1.6 9.0 74.0 0.0 111.5 52.8 5.2 17.5 31.2 66.8 5.5 17.3 19.9 17.5 7.5 5.2 9.8 5.8 7.5 0.0 10.8 6.7 0.2 1.4 12.6 4.5 22.6 16.9 12.6 11.2 9.7 MANEA "FLJ12838, mandaselin" ENSG00000172469 "Mannosidase endo-alpha" Q5SRI9 6 95577535-95609452 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 59.8;Plasma cells: 113.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011046, HPA011069" Enhanced Supported "Golgi apparatus" NA NA 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA011046: AB_1079303, HPA011069: AB_1079304" "unprognostic (6.00e-2)" "unprognostic (7.81e-2)" "prognostic favorable (3.04e-4)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (5.03e-2)" "unprognostic (2.98e-3)" "unprognostic (2.74e-1)" "unprognostic (5.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.44e-1)" "unprognostic (9.07e-2)" "unprognostic (2.86e-3)" "unprognostic (5.18e-2)" "unprognostic (3.08e-1)" "unprognostic (9.68e-2)" "unprognostic (7.47e-2)" 11.9 6.9 3.1 7.9 3.6 3.3 8.9 3.7 3.7 8.4 4.2 8.1 8.8 6.8 6.3 8.0 6.4 7.9 5.6 2.5 3.7 12.0 24.0 7.3 9.2 4.3 3.3 9.7 8.4 11.1 2.1 6.3 4.4 7.0 8.7 6.1 5.6 7.9 1.4 6.8 8.8 6.7 3.6 9.6 12.1 6.1 3.7 9.1 11.6 3.4 11.2 9.0 3.5 5.6 6.5 5.3 20.4 16.6 33.1 38.5 7.7 17.7 16.2 10.1 14.8 6.1 16.0 12.3 21.7 11.7 14.9 10.4 14.1 12.0 23.2 20.9 12.6 16.6 4.7 10.2 11.5 22.3 14.4 38.4 13.7 12.0 8.5 14.6 24.3 12.1 26.2 28.1 22.0 4.5 13.1 9.5 3.0 17.1 5.5 15.4 19.9 18.8 15.5 11.2 16.3 8.8 10.0 7.2 6.5 14.3 11.4 20.7 22.0 10.1 7.1 18.4 17.8 20.9 12.9 15.2 18.2 19.1 23.6 8.5 2.3 1.3 3.2 4.1 4.6 4.5 3.9 3.8 2.5 2.3 4.5 3.1 0.5 2.9 3.7 1.0 7.7 2.4 3.1 3.6 3.7 3.7 2.5 3.7 4.3 3.3 4.4 3.6 3.7 5.6 11.6 12.8 8.4 7.8 15.5 7.4 4.4 6.4 8.6 8.1 8.4 7.4 4.5 10.0 7.4 12.9 4.2 5.4 5.4 1.8 5.9 4.1 16.7 7.3 14.4 10.7 1.8 8.2 6.0 7.3 5.6 12.0 8.2 8.1 2.5 17.8 28.2 59.8 11.0 11.8 7.3 4.6 0.0 12.0 5.8 11.7 5.9 7.9 8.8 8.4 6.8 10.5 3.1 16.1 18.7 3.4 2.8 15.8 113.4 3.4 4.8 8.5 8.5 5.3 13.1 9.8 17.1 7.1 12.1 11.8 7.0 1.4 9.2 13.5 5.0 3.5 MAP3K12 "DLK, MEKK12, MUK, ZPK, ZPKP1" ENSG00000139625 "Mitogen-activated protein kinase kinase kinase 12" Q12852 12 53479669-53500063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 85.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 55.9;HHSteC: 53.7;HSkMC: 51.8;hTERT-RPE1: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039936, HPA071996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Plasma membrane" "HPA039936: AB_10795239, HPA071996: AB_2686481" "unprognostic (4.01e-1)" "unprognostic (3.30e-1)" "unprognostic (8.89e-3)" "unprognostic (6.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-1)" "unprognostic (6.97e-2)" "unprognostic (3.61e-2)" "unprognostic (2.39e-1)" "unprognostic (2.70e-1)" "prognostic favorable (1.51e-4)" "unprognostic (8.50e-3)" "prognostic unfavorable (5.43e-10)" "unprognostic (1.65e-2)" "unprognostic (2.44e-1)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" 12.6 7.6 12.9 5.4 15.2 3.2 10.3 25.9 19.6 23.5 4.3 13.3 3.2 22.9 4.8 4.0 18.5 14.0 8.6 15.6 11.3 8.5 1.7 11.2 4.4 11.9 11.1 21.6 3.6 7.3 22.7 6.4 13.2 9.6 3.8 13.6 4.9 10.9 2.7 5.7 8.9 14.4 8.0 9.0 7.3 9.0 13.0 6.0 8.6 6.3 2.7 14.0 12.2 13.7 0.5 15.1 8.6 14.2 55.9 28.9 1.2 10.1 18.9 10.8 11.0 0.3 1.8 3.5 5.4 10.8 8.7 0.1 4.3 6.8 4.3 4.9 5.4 3.5 8.3 0.0 53.7 0.1 3.6 51.8 5.2 14.6 7.8 69.1 16.9 7.8 0.1 15.7 10.0 6.7 3.8 0.9 3.2 0.0 5.5 5.4 6.3 1.0 5.4 0.1 9.3 12.4 5.6 6.8 14.9 1.8 4.6 10.3 12.9 10.2 10.8 4.5 2.5 6.1 8.0 0.0 16.8 6.9 10.4 0.0 0.5 0.0 0.4 0.4 0.8 0.1 0.5 0.6 0.2 0.0 0.2 0.3 1.0 0.2 0.1 0.0 0.1 0.1 12.9 15.2 25.9 19.6 15.6 11.3 11.9 11.1 13.2 8.0 13.0 13.7 11.4 6.4 14.6 21.5 8.1 0.8 2.4 0.5 4.6 28.9 5.6 5.2 0.8 7.2 6.4 1.8 37.5 1.9 12.2 4.8 9.8 6.7 1.5 11.5 27.6 10.4 3.5 1.3 21.1 1.8 2.2 11.0 2.0 15.8 12.7 7.0 15.0 7.8 4.1 30.3 19.1 2.8 2.0 10.3 2.2 1.8 8.1 8.6 0.0 8.4 8.5 19.9 5.2 10.6 11.0 4.4 2.1 8.2 6.7 5.3 7.1 14.8 5.5 85.0 6.6 23.5 10.2 2.5 2.1 2.5 1.0 2.2 11.6 12.5 4.1 3.9 MAPK7 "BMK1, ERK5, PRKM7" ENSG00000166484 "Mitogen-activated protein kinase 7" Q13164 17 19377721-19383544 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 43.1;SuSa: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018561, HPA031031" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB018561: AB_2140544, HPA031031: AB_2673706" "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.72e-1)" "unprognostic (2.90e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (5.67e-3)" "unprognostic (1.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-2)" "unprognostic (4.75e-2)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (5.71e-1)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 8.3 13.7 4.0 4.0 4.4 5.2 7.7 4.0 5.9 14.3 4.4 10.6 5.5 11.1 3.3 16.3 8.7 4.5 6.2 3.9 4.5 7.7 3.9 8.7 3.7 5.3 6.1 12.5 3.4 2.9 6.1 6.7 4.4 8.9 3.5 2.2 6.7 6.1 5.0 12.5 7.3 6.7 3.3 9.4 6.7 11.8 5.0 3.5 7.4 3.4 3.6 10.1 15.2 4.1 6.9 11.0 9.9 7.7 43.1 17.2 10.4 9.0 8.3 13.0 12.4 12.2 1.4 4.1 7.3 16.5 10.4 8.2 10.4 9.4 7.8 7.2 8.3 1.9 8.4 5.4 21.2 1.9 7.8 21.6 6.2 18.2 7.2 12.0 9.5 7.5 3.7 1.4 13.2 4.8 13.0 7.4 10.7 8.4 6.7 8.6 12.9 3.0 5.4 3.7 4.4 12.3 9.7 1.0 5.0 53.7 6.1 3.1 6.0 14.6 10.8 15.5 6.7 2.6 4.0 1.2 16.5 1.6 9.2 0.8 3.4 10.7 3.7 6.5 2.0 1.8 1.8 3.2 2.3 1.0 1.6 2.0 1.1 4.9 6.0 1.4 1.0 3.1 4.0 4.4 4.0 5.9 3.9 4.5 5.3 6.1 4.4 3.3 5.0 4.1 10.7 6.4 3.3 2.6 7.8 5.5 6.1 9.5 13.6 2.4 5.8 4.6 5.3 2.8 5.6 5.5 2.1 5.7 6.7 16.2 5.9 8.1 8.7 3.0 7.9 8.5 10.7 1.7 2.0 6.2 8.0 9.6 12.2 5.2 2.5 7.7 7.5 1.1 7.7 0.0 2.1 6.9 10.2 6.9 6.1 5.7 11.5 14.4 3.6 6.5 3.4 13.1 17.5 1.0 2.0 8.0 20.8 11.7 9.3 6.3 9.0 3.5 3.2 2.1 26.3 8.4 11.1 33.2 16.4 9.8 4.3 5.1 6.2 7.7 6.7 5.3 MARVELD1 "bA548K23.8, FLJ22343, FLJ23440, GB14, MGC4415, MRVLDC1" ENSG00000155254 "MARVEL domain containing 1" Q9BSK0 10 97713173-97718150 "Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.2;intermediate monocyte: 2.7;myeloid DC: 3.1" "Group enriched" "Detected in many" 18 "dendritic cells: 3.1;monocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 141.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (3.28e-2)" "unprognostic (2.11e-2)" "unprognostic (1.26e-3)" "unprognostic (3.05e-2)" "unprognostic (1.36e-3)" "unprognostic (8.82e-2)" "unprognostic (7.40e-3)" "prognostic unfavorable (5.85e-5)" "unprognostic (1.54e-2)" "unprognostic (7.44e-3)" "unprognostic (3.40e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (8.89e-7)" "unprognostic (3.92e-3)" "unprognostic (7.02e-2)" "unprognostic (1.50e-1)" "unprognostic (3.86e-3)" 35.9 8.9 4.7 12.6 5.4 5.2 26.7 4.5 5.5 56.8 24.5 57.1 7.7 60.0 16.7 19.7 48.1 20.4 24.8 4.6 7.5 12.4 5.6 29.7 6.9 6.4 5.7 40.5 7.0 11.3 20.0 25.0 5.5 44.3 24.5 2.0 19.1 48.5 6.1 30.8 22.3 47.7 5.8 16.0 23.7 6.8 6.6 5.3 15.9 7.0 6.0 46.5 41.3 5.9 42.0 30.7 26.1 99.9 97.8 94.0 27.0 56.4 141.3 51.6 34.5 13.5 70.4 0.0 44.5 105.1 7.3 50.3 22.4 53.5 25.9 3.2 28.0 20.3 24.6 0.0 40.9 28.6 0.0 82.7 137.5 33.2 38.3 95.3 65.0 17.6 5.7 0.1 57.7 24.1 3.8 9.9 19.5 4.5 30.6 26.1 22.4 7.0 27.4 8.9 16.9 17.8 34.0 0.3 59.7 16.0 13.4 33.7 65.8 51.9 21.2 50.7 21.4 0.0 3.1 0.1 26.5 0.1 40.2 0.0 3.2 0.0 0.0 2.7 0.1 0.0 0.0 0.1 3.1 0.0 0.0 0.1 0.0 0.0 0.7 0.8 0.0 1.0 4.7 5.4 4.5 5.5 4.6 7.5 6.4 5.7 5.5 5.8 6.6 5.9 7.0 9.6 6.3 10.7 0.9 7.6 31.4 13.4 9.6 2.5 7.1 21.0 4.4 11.5 5.7 12.9 6.2 10.5 0.1 31.9 0.0 8.3 0.7 3.1 32.3 10.5 3.0 4.6 2.3 0.9 21.0 29.9 2.0 6.3 2.5 86.6 12.8 0.6 12.9 0.0 2.8 28.9 4.1 32.6 13.4 2.9 23.0 15.6 12.4 7.5 11.7 13.7 0.0 2.5 0.6 1.9 7.0 38.7 0.3 4.0 2.0 0.2 0.7 3.2 0.0 10.0 31.9 0.3 1.6 1.0 5.4 3.4 1.2 13.1 9.4 6.9 MBTPS1 "KIAA0091, PCSK8, S1P, SKI-1" ENSG00000140943 "Membrane bound transcription factor peptidase, site 1" Q14703 16 84053761-84116942 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 318.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056109 Supported NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA056109: AB_2683040" "unprognostic (1.50e-1)" "unprognostic (9.73e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (2.50e-1)" "unprognostic (2.02e-1)" "unprognostic (1.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "prognostic favorable (2.21e-5)" "unprognostic (2.62e-1)" "unprognostic (2.92e-1)" "unprognostic (6.63e-2)" "unprognostic (6.88e-2)" 45.8 33.7 12.7 26.2 16.4 24.6 42.8 17.6 13.3 41.2 18.1 38.7 26.0 40.8 25.6 28.2 45.6 32.2 44.6 13.1 17.8 36.7 27.5 35.5 27.5 6.3 8.0 49.4 36.4 58.5 38.8 37.1 8.9 37.3 33.7 108.7 42.4 40.3 18.9 27.8 26.4 41.2 5.9 30.1 30.7 19.6 16.5 33.4 53.9 35.6 29.9 35.2 21.3 8.6 49.4 61.3 53.8 75.2 124.2 100.1 42.2 81.2 124.4 70.2 52.6 43.7 71.0 47.0 82.0 117.3 55.8 52.9 50.2 56.3 77.9 42.6 55.9 34.4 55.8 61.3 59.9 84.2 72.7 103.6 79.9 64.8 55.5 100.3 92.4 62.2 45.6 40.3 43.1 85.0 46.6 46.4 50.3 27.7 43.2 59.6 28.7 34.1 56.1 40.2 41.0 51.2 156.9 42.9 62.1 58.3 134.3 76.4 99.0 72.3 52.5 43.7 38.7 50.5 102.6 90.5 52.6 50.6 45.2 8.0 16.3 15.0 16.3 13.8 16.8 11.3 14.0 15.4 12.8 9.6 16.9 15.3 4.5 17.0 11.6 7.1 9.6 18.3 12.7 16.4 17.6 13.3 13.1 17.8 6.3 8.0 8.9 5.9 16.5 8.6 54.3 48.1 50.7 27.1 33.5 13.8 24.2 25.9 19.9 68.4 62.2 56.1 50.5 44.3 41.9 25.8 166.8 24.4 41.0 28.9 11.7 24.1 0.9 70.4 67.8 39.8 34.9 19.4 50.4 27.5 21.4 48.4 23.0 92.7 29.1 103.1 36.0 33.8 16.7 84.1 53.5 26.6 28.5 21.0 10.8 5.5 53.4 23.3 19.6 36.5 22.5 44.4 29.9 57.8 39.0 30.2 24.8 50.4 59.3 30.1 20.3 17.5 56.4 318.6 26.3 60.9 42.2 12.6 24.2 23.4 15.8 21.6 34.3 75.5 33.8 28.6 MDGA1 "GPIM, MAMDC3" ENSG00000112139 "MAM domain containing glycosylphosphatidylinositol anchor 1" Q8NFP4 6 37630679-37699306 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 79.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.0;Cone photoreceptor cells: 50.1;Horizontal cells: 57.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 9 "cerebellum: 79.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031235, HPA050382" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Golgi apparatus" "HPA031235: AB_10603017, HPA050382: AB_2681108" "unprognostic (4.67e-2)" "unprognostic (6.97e-3)" "unprognostic (3.24e-1)" "unprognostic (5.69e-4)" "unprognostic (2.75e-2)" "unprognostic (2.41e-1)" "unprognostic (1.45e-2)" "unprognostic (2.00e-1)" "unprognostic (2.02e-2)" "unprognostic (1.45e-1)" "unprognostic (2.16e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-5)" "unprognostic (9.19e-3)" "unprognostic (5.28e-3)" "unprognostic (3.80e-3)" "unprognostic (4.60e-2)" 2.6 2.9 4.2 2.6 3.9 0.3 1.6 79.9 5.3 5.4 0.0 2.6 0.5 3.4 1.8 3.7 2.7 3.2 2.3 8.8 4.9 1.2 0.6 3.1 2.6 4.3 4.7 6.5 2.4 4.1 4.8 0.3 7.4 2.1 1.1 4.0 1.1 1.3 1.1 4.9 2.8 2.5 1.0 3.1 2.0 1.5 2.1 0.8 1.4 1.7 2.1 1.9 4.4 3.2 0.2 3.5 4.8 2.4 12.3 4.3 2.2 2.8 2.2 3.5 3.2 0.0 0.0 0.7 0.5 1.7 3.0 5.4 0.5 0.0 1.0 4.9 3.4 0.0 0.3 0.0 0.5 0.0 1.1 1.0 0.0 1.4 0.0 6.8 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.0 0.1 0.4 5.9 1.7 0.0 0.8 3.7 4.3 0.0 1.5 0.3 2.6 0.2 3.1 0.6 0.3 3.4 1.4 1.2 4.3 0.0 0.1 0.0 4.2 1.0 2.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.1 4.2 3.9 79.9 5.3 8.8 4.9 4.3 4.7 7.4 1.0 2.1 3.2 3.0 9.6 0.5 12.7 2.0 2.3 2.4 0.7 1.2 34.0 0.4 0.6 5.7 1.5 0.8 3.7 50.1 0.2 3.1 0.0 0.0 0.5 2.6 0.6 1.8 1.6 1.8 0.0 4.9 0.0 1.4 4.4 0.5 0.5 0.0 1.1 1.4 0.0 0.1 57.2 4.9 0.0 0.0 0.3 1.1 0.2 10.2 0.3 1.8 1.9 0.0 2.6 4.1 4.0 2.1 0.6 0.0 4.9 1.7 2.0 0.0 0.5 1.9 2.0 0.0 2.6 3.0 2.1 1.3 2.8 3.0 0.7 2.9 0.2 0.0 5.1 MEDAG "AWMS3, C13orf33, FLJ14834, MEDA-4" ENSG00000102802 "Mesenteric estrogen dependent adipogenesis" Q5VYS4 13 30906271-30925572 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 163.7" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 80.2;Fibroblasts: 122.4;Skeletal myocytes: 80.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 312.4;ASC TERT1: 87.4;U-2197: 175.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (2.28e-1)" "unprognostic (1.08e-1)" "unprognostic (6.44e-2)" "unprognostic (3.42e-2)" "unprognostic (6.06e-3)" "unprognostic (8.80e-2)" "unprognostic (1.07e-1)" "unprognostic (3.71e-3)" "unprognostic (1.37e-1)" "unprognostic (1.50e-1)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (8.69e-3)" "unprognostic (2.48e-1)" "unprognostic (5.41e-3)" "unprognostic (7.52e-2)" 163.7 4.0 0.6 15.8 0.8 0.3 57.0 0.5 1.5 19.1 4.6 14.5 2.5 28.1 26.9 8.4 36.3 15.1 30.1 0.6 1.9 11.6 0.8 16.0 1.5 0.7 0.8 11.8 14.2 0.8 6.1 6.8 0.7 7.5 6.5 0.1 15.5 2.5 14.8 21.4 11.5 23.4 0.7 0.4 15.4 7.0 1.1 1.9 26.8 6.2 0.8 66.4 10.1 0.5 0.0 0.0 0.0 0.0 312.4 87.4 0.0 0.6 0.1 1.3 1.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.6 0.5 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.1 37.1 0.0 45.9 0.0 0.2 42.7 0.0 0.0 0.0 4.2 0.0 0.0 0.2 4.0 0.0 0.0 0.0 37.9 0.0 0.0 0.0 6.6 0.0 0.0 0.3 0.0 6.0 0.1 0.0 46.9 0.0 0.2 175.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.5 1.5 0.6 1.9 0.7 0.8 0.7 0.7 1.1 0.5 12.0 0.0 0.5 0.3 0.0 11.5 0.2 0.1 0.0 0.0 0.1 0.3 4.5 5.7 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.9 1.1 2.0 80.2 13.9 0.0 0.0 0.4 0.0 0.5 122.4 2.0 1.7 0.0 0.0 2.2 0.0 1.0 0.0 0.3 0.0 0.0 0.0 20.6 2.2 19.0 1.4 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 9.8 0.1 1.7 0.0 0.2 0.7 0.0 0.0 80.4 19.6 0.0 0.0 0.7 10.4 0.3 1.1 5.3 0.0 0.6 MEGF8 "C19orf49, EGFL4, FLJ22365, SBP1" ENSG00000105429 "Multiple EGF like domains 8" Q7Z7M0 19 42325609-42378769 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 38.7;Cone photoreceptor cells: 77.2;Horizontal cells: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049248 Approved NA NA 510000000 "Cluster 11: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "HPA049248: AB_2680691" "unprognostic (5.52e-3)" "unprognostic (1.52e-1)" "unprognostic (5.35e-2)" "unprognostic (1.66e-2)" "unprognostic (1.20e-1)" "unprognostic (4.63e-2)" "unprognostic (3.25e-2)" "unprognostic (8.58e-2)" "unprognostic (9.25e-2)" "unprognostic (3.64e-2)" "prognostic favorable (6.03e-4)" "unprognostic (4.33e-2)" "prognostic favorable (2.17e-7)" "unprognostic (1.18e-1)" "unprognostic (7.34e-2)" "unprognostic (1.06e-2)" "unprognostic (1.08e-1)" 13.0 12.3 23.4 4.3 20.9 2.3 10.0 11.1 30.6 10.4 6.7 11.8 4.8 11.9 7.0 7.3 9.7 4.6 16.6 21.7 18.0 11.3 6.9 6.8 3.9 16.1 19.7 13.5 8.7 20.5 12.3 6.1 17.4 10.0 4.3 10.9 8.5 8.1 10.2 6.8 8.6 6.7 12.1 9.1 9.3 7.9 23.0 3.8 10.7 6.8 3.3 10.2 7.9 17.3 12.7 21.1 22.2 5.5 48.6 23.1 8.2 10.6 14.8 6.0 9.3 4.2 11.6 10.7 22.4 14.7 7.9 6.6 16.2 13.8 6.0 13.1 14.1 8.0 10.3 6.9 18.7 10.9 9.5 28.0 13.6 7.3 10.9 39.9 20.7 3.1 11.8 4.7 11.3 8.3 2.5 6.6 11.3 11.5 3.5 10.4 20.0 2.4 16.1 16.6 11.5 29.3 13.0 6.8 14.4 23.8 7.2 24.3 31.1 12.7 12.3 4.0 14.6 10.9 6.4 5.9 13.8 6.5 31.2 0.4 0.2 0.2 0.1 0.3 0.1 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.1 23.4 20.9 11.1 30.6 21.7 18.0 16.1 19.7 17.4 12.1 23.0 17.3 6.2 6.4 10.8 13.7 3.2 2.2 2.4 7.3 4.6 38.7 5.7 6.3 15.9 2.8 10.3 7.3 77.2 3.7 3.2 8.4 0.0 7.2 3.4 7.9 9.8 7.0 13.2 1.7 24.4 3.7 1.5 9.2 4.6 6.7 3.8 26.2 7.1 8.9 5.9 40.4 27.2 6.7 6.1 4.7 3.9 1.2 12.8 3.2 8.8 8.4 4.0 13.1 2.1 10.1 10.0 4.6 3.1 14.3 3.2 2.6 5.4 4.4 7.2 16.3 0.0 11.9 8.9 5.9 4.2 5.7 1.0 2.3 2.5 18.9 10.9 1.4 METTL7A DKFZP586A0522 ENSG00000185432 "Methyltransferase like 7A" Q9H8H3 12 50923472-50932510 "Metabolic proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 440.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 986.4;Kupffer cells: 308.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 95.7;classical monocyte: 35.7;eosinophil: 70.7;intermediate monocyte: 38.0;memory B-cell: 32.4;myeloid DC: 31.0;naive B-cell: 34.4;non-classical monocyte: 59.5;plasmacytoid DC: 25.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 420.7;Karpas-707: 401.7;RPMI-8226: 238.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA017434 Supported "Lipid droplets" NA NA 18000 "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "Lipid droplets" "HPA017434: AB_1853835" "unprognostic (2.31e-2)" "unprognostic (2.82e-2)" "unprognostic (9.85e-3)" "unprognostic (9.43e-2)" "unprognostic (1.52e-1)" "unprognostic (3.38e-2)" "unprognostic (1.09e-3)" "unprognostic (2.68e-3)" "unprognostic (5.48e-2)" "unprognostic (9.94e-2)" "unprognostic (2.57e-2)" "unprognostic (4.49e-2)" "prognostic favorable (0.00e+0)" "unprognostic (8.64e-2)" "unprognostic (5.94e-2)" "unprognostic (1.39e-1)" "unprognostic (1.22e-2)" 143.6 86.7 59.6 35.2 71.9 15.2 54.6 66.1 53.6 43.9 67.7 67.7 62.8 42.9 29.7 39.1 89.1 79.6 28.1 48.4 66.9 144.9 440.5 60.1 49.4 79.6 79.1 90.7 115.6 48.1 17.3 25.4 69.0 28.5 63.3 15.5 60.7 41.6 64.6 26.1 60.5 62.0 61.9 53.6 87.4 19.3 68.8 29.7 243.2 53.2 50.2 50.7 35.4 68.0 1.5 0.2 8.4 61.3 420.7 115.0 130.0 1.1 8.9 1.0 1.5 4.7 5.2 69.7 5.2 4.6 1.0 8.2 6.1 6.9 0.3 7.1 15.4 17.0 11.1 43.2 88.0 4.5 33.7 118.0 0.9 0.9 0.5 2.1 26.9 2.5 10.1 401.7 3.9 0.0 3.3 19.8 44.6 1.6 0.0 3.7 0.5 238.2 20.3 79.1 21.9 37.3 1.5 41.0 1.0 11.5 114.4 4.1 17.1 1.0 1.2 4.8 0.5 18.7 3.7 30.3 7.8 8.4 0.5 95.7 35.7 70.7 2.4 38.0 1.5 32.4 1.0 2.2 31.0 34.4 0.3 1.6 2.1 10.3 59.5 25.3 9.4 17.7 59.6 71.9 66.1 53.6 48.4 66.9 79.6 79.1 69.0 61.9 68.8 68.0 73.5 201.9 125.6 96.0 47.2 8.7 53.4 41.8 30.1 2.9 37.4 26.7 14.1 240.2 72.5 71.7 0.0 76.7 19.9 159.0 43.0 11.9 2.2 64.2 48.1 43.5 67.9 131.8 4.1 37.3 29.6 83.0 75.4 28.4 32.9 16.5 140.7 986.4 37.3 8.4 5.1 64.4 30.5 308.8 23.1 10.6 216.6 73.2 12.4 45.0 59.8 114.2 29.9 43.2 10.6 3.5 59.3 149.0 65.7 30.2 134.6 145.6 263.1 5.3 52.6 57.3 42.2 1.6 1.4 28.3 9.2 38.3 12.9 52.7 74.8 46.2 MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Fibroblasts: 903.5;Peritubular cells: 240.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 394.8;ASC TERT1: 597.9;fHDF/TERT166: 284.0;HHSteC: 275.4;HSkMC: 417.8;MOLT-4: 375.8;SH-SY5Y: 350.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" 271.8 81.9 6.5 74.0 10.0 2.7 197.7 7.0 9.5 326.1 13.1 287.5 102.0 237.3 289.0 293.2 227.5 646.2 273.2 6.1 8.3 61.4 45.6 634.7 65.7 7.7 9.0 325.8 71.3 7.0 87.5 156.7 6.6 226.7 139.1 17.3 108.1 129.8 41.6 144.7 187.6 262.7 6.9 59.8 176.1 31.8 8.1 42.4 114.5 249.7 78.6 488.8 244.6 6.9 0.3 0.7 0.6 0.1 394.8 597.9 0.8 44.8 160.0 4.6 3.2 0.2 0.0 0.2 0.1 284.0 0.1 0.2 0.1 0.0 0.8 0.3 1.2 0.0 0.3 0.0 275.4 14.4 0.2 417.8 0.0 2.6 0.1 4.7 0.0 3.9 0.1 0.0 0.4 0.0 375.8 33.8 7.1 0.1 0.4 26.4 24.9 0.7 0.0 0.2 35.8 350.2 0.4 0.2 0.3 2.4 0.4 82.4 0.2 50.9 3.3 2.3 0.1 0.4 0.5 0.1 48.9 15.4 0.1 0.0 0.1 1.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 6.5 10.0 7.0 9.5 6.1 8.3 7.7 9.0 6.6 6.9 8.1 6.9 35.1 3.2 12.1 0.0 0.3 47.5 0.7 0.2 5.7 0.7 2.3 4.2 10.7 0.0 3.1 1.8 0.0 7.2 1.3 0.0 0.0 0.2 0.7 0.3 21.4 15.9 0.0 0.0 0.0 0.0 3.6 903.5 6.1 0.4 1.3 0.1 15.4 0.2 9.4 0.0 0.0 0.0 0.0 0.0 62.9 6.3 78.3 3.9 67.6 14.0 0.0 80.2 0.0 0.5 0.1 0.1 0.0 240.0 2.6 2.2 0.0 0.0 2.9 3.3 19.7 38.6 103.1 0.4 0.5 8.8 41.1 19.4 6.9 0.2 0.0 2.2 MFGE8 "BA46, EDIL1, hP47, HsT19888, MFG-E8, OAcGD3S, SED1, SPAG10" ENSG00000140545 "Milk fat globule EGF and factor V/VIII domain containing" Q08431 15 88898683-88913381 "Cancer-related genes, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 407.0;Cone photoreceptor cells: 385.7;Rod photoreceptor cells: 978.7;Sertoli cells: 1084.7;Smooth muscle cells: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.9" "Group enriched" "Detected in many" 8 "granulocytes: 5.3;NK-cells: 7.7;T-cells: 14.9" "Cell line enhanced" "Detected in many" "ASC diff: 1784.6;ASC TERT1: 918.2;fHDF/TERT166: 660.4;HSkMC: 935.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002753, HPA002807" Enhanced Approved Cytosol "Secreted to blood" NA NA 2830000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "CAB002753: , HPA002807: AB_1078072" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.63e-2)" "unprognostic (7.68e-2)" "unprognostic (2.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (8.11e-3)" "unprognostic (6.27e-2)" "unprognostic (8.49e-2)" "unprognostic (3.99e-1)" "prognostic unfavorable (6.06e-9)" "prognostic unfavorable (3.08e-4)" "unprognostic (4.85e-2)" "unprognostic (7.36e-3)" "unprognostic (2.41e-3)" 237.2 95.2 44.2 45.2 49.6 3.7 226.7 56.4 61.8 272.8 52.4 113.7 21.2 444.7 77.0 67.6 361.8 120.2 485.8 41.6 47.2 69.0 15.6 137.2 47.4 55.9 47.4 228.5 36.5 18.9 49.3 79.6 55.6 129.3 29.3 68.7 97.1 195.8 264.3 118.9 106.9 162.7 47.0 40.7 124.9 38.3 46.5 18.8 90.6 124.1 36.9 163.6 223.4 55.6 19.7 85.4 78.7 98.7 1784.6 918.2 6.9 482.7 142.4 95.4 110.3 90.5 23.5 0.0 147.5 660.4 144.6 10.2 27.6 95.8 31.1 82.3 64.7 138.1 4.6 10.2 469.8 0.2 50.1 935.7 251.8 73.5 122.5 205.3 37.0 35.3 23.4 41.1 185.1 6.2 22.6 3.2 405.4 8.3 38.4 22.7 74.4 26.4 32.6 7.3 8.2 42.9 28.0 2.5 226.1 165.6 2.4 11.1 42.0 233.2 127.8 62.3 36.3 145.3 30.5 15.9 31.6 12.2 91.5 5.3 0.2 0.4 1.3 0.0 4.2 1.2 4.2 2.9 0.0 0.9 4.3 3.3 0.0 7.7 0.1 0.1 14.9 2.1 44.2 49.6 56.4 61.8 41.6 47.2 55.9 47.4 55.6 47.0 46.5 55.6 72.1 12.8 5.4 39.2 4.0 48.7 32.2 116.3 24.5 22.1 407.0 190.4 92.8 8.6 25.5 3.7 385.7 4.5 13.1 1.6 0.0 15.7 11.0 33.3 202.2 66.9 44.8 3.8 5.1 4.3 18.6 220.0 12.8 29.7 5.1 30.1 22.1 15.5 8.1 16.8 0.4 6.4 36.7 32.9 39.7 27.9 187.0 12.9 119.2 15.0 1.8 75.9 9.2 5.5 9.6 28.3 0.2 109.1 8.8 15.8 0.1 0.2 8.3 978.7 1084.7 51.8 476.0 3.3 9.0 21.7 35.9 5.3 12.5 25.8 2.0 10.2 MGST1 "GST12, MGST-I" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1096.9;adrenal gland: 1137.3;liver: 3104.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1205.9;Club cells: 1308.7;Hepatocytes: 4345.6;Proximal tubular cells: 1265.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 170.2;myeloid DC: 123.5" "Group enriched" "Detected in many" 13 "dendritic cells: 123.5;monocytes: 170.2" "Cell line enhanced" "Detected in many" "ASC diff: 5391.4;ASC TERT1: 2078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 19000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favorable (1.97e-4)" "unprognostic (4.19e-1)" 1096.9 1137.3 139.2 76.1 143.9 79.3 574.8 131.4 200.7 69.7 111.9 315.5 128.9 32.7 43.9 195.3 78.4 200.8 135.1 133.9 165.4 392.9 3104.7 177.2 3.5 156.5 155.7 11.4 131.3 0.8 52.6 14.2 166.6 161.2 212.8 7.0 155.3 55.8 25.5 88.8 119.5 44.7 146.4 7.3 131.4 20.2 147.5 14.0 272.3 43.3 7.7 267.9 114.7 132.9 1.4 495.2 115.6 139.4 5391.4 2078.4 1.5 408.5 418.5 220.6 339.1 186.0 838.6 0.4 48.5 535.8 694.2 2.4 317.0 663.5 202.9 1.1 41.4 175.7 256.6 664.8 1252.0 350.4 1.2 1375.9 714.7 671.2 710.5 540.4 393.1 0.1 126.7 0.6 486.3 101.2 0.3 137.0 987.6 0.7 391.2 0.4 69.3 229.3 503.3 982.1 21.8 17.1 645.8 411.8 17.5 630.1 442.5 190.8 248.0 226.1 30.5 447.3 541.1 0.6 1.7 1.5 748.1 538.5 7.1 11.3 170.2 1.8 0.1 26.3 0.5 1.0 0.2 0.1 123.5 0.0 0.1 0.1 5.9 0.2 5.9 34.1 1.1 55.9 139.2 143.9 131.4 200.7 133.9 165.4 156.5 155.7 166.6 146.4 147.5 132.9 39.6 266.0 651.3 130.2 14.0 25.6 130.2 1205.9 91.0 0.0 383.8 262.6 5.1 574.7 1308.7 71.7 0.0 2.9 9.8 288.1 181.9 26.9 25.4 299.9 198.2 19.6 45.6 92.8 4.4 434.1 218.1 404.5 153.9 947.9 34.1 26.3 67.5 4345.6 160.2 0.0 0.5 280.5 740.6 176.4 52.0 17.9 33.2 75.7 39.2 6.5 224.4 1.0 5.2 1.0 0.8 322.7 175.0 113.2 6.0 467.2 209.5 1265.6 526.1 1.3 0.0 11.3 124.3 0.7 2.3 510.3 17.6 7.9 22.1 152.4 534.1 883.3 MIA3 "FLJ39207, KIAA0268, TANGO, TANGO1, UNQ6077" ENSG00000154305 "MIA SH3 domain ER export factor 3" Q5JRA6 1 222618097-222668007 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA055922, HPA056816" Supported Enhanced Vesicles NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "HPA055922: AB_2682971, HPA056816: AB_2683243" "unprognostic (1.24e-1)" "unprognostic (7.42e-2)" "unprognostic (1.43e-1)" "unprognostic (6.60e-2)" "unprognostic (1.86e-2)" "unprognostic (8.57e-2)" "unprognostic (1.28e-3)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (5.65e-2)" "unprognostic (6.73e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (3.57e-2)" "unprognostic (1.83e-1)" "unprognostic (8.62e-3)" "unprognostic (3.26e-1)" 25.6 22.0 11.0 23.4 13.1 33.2 21.4 12.9 14.9 23.9 13.2 24.3 23.9 23.7 29.2 13.7 16.0 20.6 20.6 10.9 13.6 21.1 74.5 21.5 26.9 10.8 12.3 25.4 38.7 30.1 15.2 23.1 11.7 39.3 29.5 24.4 33.2 22.1 23.7 17.4 25.9 23.8 10.7 27.3 45.0 36.5 11.5 25.7 31.7 20.5 26.2 21.0 14.1 12.8 24.8 18.8 26.5 42.5 92.8 47.1 46.5 34.8 49.4 36.2 43.1 16.6 26.2 24.0 33.0 41.8 20.5 39.9 28.5 31.3 37.8 38.1 21.6 27.7 21.5 31.5 88.6 50.7 34.7 45.2 35.0 35.9 60.8 44.8 41.4 28.9 34.8 44.4 30.7 15.9 34.3 33.8 33.2 76.8 27.5 24.4 70.8 47.8 23.1 22.8 30.4 31.3 38.6 36.2 30.4 36.2 38.2 37.5 31.7 27.5 17.9 44.5 41.3 48.4 30.9 23.8 36.7 25.4 37.5 26.8 15.6 36.5 17.6 22.4 17.7 20.7 14.7 17.5 11.7 18.6 16.4 17.8 27.1 22.5 26.0 13.2 19.2 13.5 11.0 13.1 12.9 14.9 10.9 13.6 10.8 12.3 11.7 10.7 11.5 12.8 48.5 70.5 49.6 31.3 46.9 18.7 26.8 20.4 29.0 60.9 24.3 35.3 65.0 25.8 47.1 5.5 31.3 28.6 73.8 35.2 0.0 25.1 37.0 34.9 72.5 36.4 60.4 26.3 51.4 34.8 17.0 53.0 79.5 42.0 17.7 44.2 25.4 63.3 20.4 45.4 58.0 95.3 32.6 22.0 14.0 24.9 37.0 32.9 19.6 35.6 32.1 31.8 44.3 41.2 29.1 26.4 25.8 48.9 54.4 39.0 41.3 19.4 44.7 41.5 19.7 57.9 46.6 55.7 42.1 21.9 16.1 35.8 47.8 70.2 24.6 29.4 MMD "MMA, PAQR11" ENSG00000108960 "Monocyte to macrophage differentiation associated" Q15546 17 55392622-55421924 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adipose tissue: 152.2;brain: 87.5" "Cell type enhanced" "Detected in many" "Kupffer cells: 56.4;Macrophages: 85.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 110.0;HSkMC: 199.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026978 Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA026978: AB_2672068" "unprognostic (1.33e-1)" "unprognostic (2.92e-2)" "prognostic favorable (3.52e-5)" "prognostic unfavorable (3.88e-4)" "unprognostic (2.48e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (6.39e-5)" "unprognostic (8.07e-3)" "unprognostic (6.67e-2)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.06e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (3.71e-3)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.12e-2)" 152.2 13.3 54.2 15.7 55.9 14.1 28.4 11.6 58.5 4.8 5.4 13.4 10.9 6.2 9.7 7.2 4.2 9.4 6.5 87.5 19.7 8.5 13.2 10.0 17.8 16.3 29.2 2.8 3.5 3.7 4.8 21.4 16.1 6.2 12.9 12.8 4.9 7.9 3.4 5.3 10.1 11.4 24.2 16.5 5.4 17.0 21.6 8.2 6.6 8.0 12.1 11.6 4.0 27.2 20.1 46.3 67.0 13.5 110.0 86.0 39.2 13.6 5.2 7.2 10.2 7.4 53.8 30.1 39.6 4.5 20.1 1.5 18.8 14.3 14.9 41.5 9.5 11.0 2.5 85.2 29.8 10.8 3.2 199.4 4.5 10.1 11.4 15.7 9.0 27.4 4.4 20.5 15.1 2.8 29.7 8.2 20.6 3.3 15.6 12.4 46.9 10.0 19.7 5.0 7.0 72.8 5.0 7.1 10.9 41.5 15.4 17.3 9.6 18.7 26.6 15.5 14.0 13.1 6.2 45.7 26.7 8.5 15.2 14.2 1.5 1.9 1.7 2.1 4.9 4.5 1.8 3.3 4.3 5.0 3.1 3.3 4.6 2.9 1.9 1.3 2.1 17.5 54.2 55.9 11.6 58.5 87.5 19.7 16.3 29.2 16.1 24.2 21.6 27.2 15.5 3.2 0.6 5.2 20.3 5.4 23.7 9.3 5.2 28.2 3.3 3.3 4.6 11.5 2.7 7.3 4.2 11.5 12.2 3.4 15.6 27.7 2.5 4.8 8.9 16.4 7.8 27.3 36.5 1.3 18.8 12.7 2.6 8.7 0.0 3.5 19.6 17.9 37.6 16.8 11.5 6.8 8.2 56.4 35.9 4.0 1.8 85.9 7.2 14.0 48.6 14.5 12.3 7.5 7.2 17.3 1.6 3.4 12.1 26.2 2.3 9.8 2.4 10.2 19.7 5.2 11.4 28.9 23.3 3.1 17.5 20.0 17.7 1.3 8.6 6.1 MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183704 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 333.5;kidney: 302.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 273.3;Proximal enterocytes: 372.4;Proximal tubular cells: 125.7;Syncytiotrophoblasts: 126.0" "Cancer enhanced" "Detected in many" "prostate cancer: 17.6" "Group enriched" "Detected in many" 5 "basal ganglia: 17.3;medulla oblongata: 9.3;pons: 10.9;thalamus: 4.6" "Immune cell enriched" "Detected in some" 122 "neutrophil: 139.4" "Lineage enriched" "Detected in many" 122 "granulocytes: 139.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 684.4;BJ hTERT+: 1116.9;HSkMC: 651.1" "Region enhanced" "Detected in many" "basal ganglia: 28.1" "Group enriched" "Detected in many" 4 "basal ganglia: 32.3;olfactory bulb: 8.5;spinal cord: 15.9" "CAB000013, HPA052583, HPA056072" Enhanced NA NA 320000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "CAB000013: AB_563478, HPA052583: AB_2681872, HPA056072: AB_2683027" "unprognostic (1.36e-1)" "unprognostic (1.02e-3)" "unprognostic (8.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.78e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (7.30e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-1)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (1.37e-2)" 103.9 1.0 0.7 4.5 17.3 11.5 38.5 1.5 1.9 22.7 0.3 1.9 333.5 13.3 22.5 2.3 1.9 13.4 4.3 0.1 0.6 302.5 56.1 27.6 10.3 9.3 2.3 0.9 1.2 0.5 0.6 73.0 10.9 79.6 3.4 0.1 6.1 44.5 20.3 1.9 289.7 1.5 0.9 7.9 1.6 1.3 4.6 16.6 1.2 23.5 12.3 6.0 7.6 0.4 0.1 0.0 0.9 0.3 280.1 684.4 1.6 160.3 1116.9 82.2 209.8 0.0 0.3 172.9 0.1 130.1 107.4 0.5 5.2 6.1 201.3 0.0 0.8 0.0 0.1 0.2 229.6 0.0 0.0 651.1 1.0 40.4 308.1 89.4 59.5 0.4 0.2 0.3 135.1 0.7 0.4 1.0 6.1 0.5 1.1 303.3 139.9 1.6 5.2 1.9 0.5 1.5 0.1 0.5 31.9 68.3 0.2 0.2 165.8 356.4 0.8 115.7 27.9 0.1 0.0 217.3 42.5 0.1 7.3 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 139.4 0.0 0.0 1.1 0.0 0.0 0.7 17.3 1.5 1.9 0.1 0.6 9.3 2.3 10.9 0.9 4.6 0.4 5.9 9.6 13.0 0.3 2.3 0.8 74.1 2.5 0.0 0.0 1.5 64.1 1.6 21.5 11.2 22.0 0.0 82.1 6.9 0.0 9.8 0.2 0.5 6.2 273.3 6.6 0.0 0.0 2.2 0.0 57.8 40.6 0.0 5.7 2.5 0.0 2.9 53.2 8.9 0.0 8.1 9.9 2.0 3.1 1.2 0.5 4.1 10.7 0.0 0.0 0.2 0.0 0.0 0.5 0.3 0.6 13.8 1.2 0.1 40.0 372.4 125.7 1.6 0.0 0.0 17.4 11.1 0.2 0.5 0.1 0.3 126.0 2.5 0.1 12.6 33.6 MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 244.0;Pancreatic endocrine cells: 144.7;Syncytiotrophoblasts: 122.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 923.8;HHSteC: 794.2;HSkMC: 887.0;hTERT-RPE1: 925.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 1400000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: AB_2681484" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" 151.5 31.7 5.6 59.9 5.0 1.6 101.5 5.7 7.5 181.3 61.8 77.2 39.5 167.3 19.0 92.1 82.1 148.2 41.3 6.6 7.2 35.9 13.2 91.8 24.8 11.9 8.4 90.2 36.0 65.3 14.2 118.9 9.2 59.9 36.6 9.6 78.1 45.5 18.8 127.5 69.4 106.0 7.3 30.8 57.7 11.7 13.2 13.0 50.0 16.1 30.8 103.9 111.1 10.6 90.6 1.2 26.3 2.0 923.8 651.6 455.9 270.1 606.4 93.3 158.5 21.3 337.4 0.9 146.4 301.9 24.6 216.3 0.3 262.2 99.7 1.1 0.6 37.2 1.7 5.0 794.2 0.4 1.3 887.0 148.7 334.7 288.3 925.5 492.9 0.6 0.8 2.1 185.1 0.7 0.4 79.4 14.7 17.7 52.4 2.1 96.0 0.2 61.4 148.1 0.3 0.6 187.3 0.3 574.2 104.4 1.0 79.5 436.8 724.9 53.7 198.2 329.6 0.8 1.6 1.1 410.9 0.6 396.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 5.0 5.7 7.5 6.6 7.2 11.9 8.4 9.2 7.3 13.2 10.6 13.9 12.8 3.0 2.0 3.4 34.0 23.4 105.4 39.3 0.0 14.1 17.5 4.7 50.1 42.2 7.3 0.0 105.6 0.3 19.9 11.7 63.0 0.4 16.1 81.6 35.2 7.8 0.0 0.0 28.7 244.0 84.0 25.5 14.8 3.8 9.3 32.9 2.7 89.5 0.0 0.0 24.5 34.6 20.2 32.7 2.4 72.1 38.0 37.4 4.7 21.5 14.3 0.0 0.5 0.1 144.7 33.0 54.9 0.3 21.8 19.9 11.7 46.8 0.8 39.5 11.1 73.9 0.8 0.8 33.7 34.2 122.7 2.5 15.6 18.6 37.9 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MPV17 SYM1 ENSG00000115204 "Mitochondrial inner membrane protein MPV17" P39210 2 27309492-27325680 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (9.34e-3)" "unprognostic (2.70e-1)" "unprognostic (9.50e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (6.99e-6)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (1.56e-1)" "unprognostic (2.22e-1)" "unprognostic (1.48e-1)" "unprognostic (1.44e-3)" "unprognostic (2.59e-3)" "unprognostic (2.52e-1)" "unprognostic (5.10e-3)" "unprognostic (4.62e-2)" 50.2 86.5 56.4 37.8 58.1 31.3 39.9 59.1 58.4 36.0 59.3 32.5 25.0 37.9 47.7 32.6 37.7 36.7 78.2 56.3 59.1 48.6 22.6 39.1 43.2 58.8 57.1 43.7 33.2 70.0 38.9 35.0 58.1 34.1 34.1 26.7 35.9 35.0 18.3 32.0 27.5 57.7 56.9 37.1 29.1 15.5 60.3 46.0 51.6 30.0 48.1 44.9 28.1 63.2 74.1 68.2 49.7 42.6 202.7 237.0 46.6 70.8 143.6 67.2 60.7 55.0 52.0 41.5 72.8 97.2 124.0 61.3 64.1 134.1 69.5 56.9 63.7 79.5 58.8 105.6 125.4 47.3 48.7 229.3 116.3 118.6 169.4 94.3 100.2 49.8 77.0 77.1 113.9 107.4 46.9 71.5 55.7 106.7 69.1 64.6 73.2 85.2 149.2 58.5 33.1 107.2 37.6 43.7 82.1 49.3 49.0 60.6 88.6 67.0 68.8 83.4 76.4 108.1 106.1 130.4 109.2 105.4 76.1 59.5 93.7 42.9 59.3 81.4 64.4 84.5 60.5 67.4 120.5 73.6 58.0 67.8 7.8 76.0 81.7 87.4 81.4 92.1 56.4 58.1 59.1 58.4 56.3 59.1 58.8 57.1 58.1 56.9 60.3 63.2 36.0 25.6 29.3 10.7 26.3 17.2 32.8 69.2 33.0 20.5 49.5 52.8 48.9 18.6 46.5 33.1 8.4 51.1 26.3 8.8 64.6 43.3 27.4 17.3 32.6 35.9 16.8 21.6 18.4 24.3 60.2 37.5 12.2 17.5 42.5 28.7 28.2 9.9 116.9 8.4 22.7 15.0 59.0 28.5 24.0 34.2 35.4 33.7 40.9 8.4 38.1 38.9 28.8 13.6 15.5 20.7 12.9 35.0 31.4 32.1 17.6 87.1 36.7 12.7 0.0 30.1 30.8 15.5 21.2 33.9 18.8 59.4 22.2 41.8 17.7 30.7 MR1 HLALS ENSG00000153029 "Major histocompatibility complex, class I-related" Q95460 1 181033425-181061938 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048304 Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA048304: AB_2680347" "unprognostic (6.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.31e-2)" "unprognostic (1.96e-1)" "unprognostic (8.66e-3)" "unprognostic (4.37e-2)" "unprognostic (1.96e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.18e-1)" "unprognostic (3.49e-2)" "unprognostic (6.41e-2)" "unprognostic (1.05e-2)" "unprognostic (7.40e-3)" "unprognostic (4.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.07e-2)" 8.6 9.6 3.2 14.2 3.3 11.1 9.7 2.2 3.5 10.2 5.8 6.7 7.4 9.5 9.6 9.6 10.4 12.7 6.2 3.1 3.8 9.9 10.6 18.0 14.6 4.7 3.3 13.6 3.7 14.0 8.9 13.5 3.7 10.9 8.1 1.5 5.9 10.5 2.1 8.7 6.9 12.5 3.8 12.3 8.7 2.6 4.4 20.2 16.7 3.8 15.2 16.3 7.4 4.8 7.9 5.4 0.1 4.6 32.2 38.8 13.9 15.5 42.2 12.7 21.5 2.2 31.9 9.7 31.6 28.1 9.9 20.5 0.7 18.3 11.1 29.6 5.2 14.2 5.6 9.8 10.8 11.5 40.6 25.2 49.6 18.9 20.3 23.7 1.3 17.8 26.7 25.6 24.9 8.8 12.1 8.3 0.1 0.1 0.8 13.7 0.3 27.3 13.9 23.1 0.2 0.3 8.2 14.8 10.9 6.0 15.4 24.6 8.1 12.5 1.7 21.8 7.7 42.2 15.3 17.9 11.7 14.7 1.2 32.6 21.8 22.9 16.3 27.4 14.6 14.3 14.6 14.6 18.8 18.3 10.8 16.2 14.7 19.0 23.6 10.2 17.0 15.2 3.2 3.3 2.2 3.5 3.1 3.8 4.7 3.3 3.7 3.8 4.4 4.8 4.4 19.2 32.4 8.8 14.7 5.0 8.3 32.6 12.0 0.8 7.7 6.1 4.1 8.6 20.9 14.7 0.0 17.5 15.9 1.6 5.9 10.8 0.3 5.9 12.1 4.9 2.4 11.4 3.1 6.4 9.5 12.8 2.6 7.3 17.1 13.5 3.6 8.9 25.8 0.0 1.7 2.7 32.6 25.2 9.1 0.4 10.8 25.3 7.2 11.2 30.8 4.1 26.8 0.0 0.5 7.5 4.5 12.0 9.1 7.4 2.2 2.4 15.3 0.6 0.0 8.6 9.2 0.4 1.6 10.9 5.4 24.5 15.7 22.4 3.5 13.4 MRGPRF "GPR140, GPR168, MGC21621, mrgF" ENSG00000172935 "MAS related GPR family member F" Q96AM1 11 69004395-69013382 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 171.2;intestine: 159.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 33.3;Leydig cells: 66.2;Peritubular cells: 100.8;Sertoli cells: 52.6;Smooth muscle cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 67.6;ASC TERT1: 30.0;BJ: 39.5;BJ hTERT+: 99.1;BJ hTERT+ SV40 Large T+: 36.8;fHDF/TERT166: 30.8;U-2197: 46.8" "Region enriched" "Detected in many" 5 "cerebellum: 14.8" "Region enhanced" "Detected in some" "spinal cord: 4.8" HPA028811 Approved Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear membrane, Plasma membrane" "HPA028811: AB_10603875" "unprognostic (2.49e-2)" "unprognostic (3.89e-2)" "unprognostic (1.20e-1)" "unprognostic (9.03e-2)" "unprognostic (5.16e-2)" "unprognostic (6.52e-3)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (4.55e-7)" "unprognostic (2.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.86e-2)" "unprognostic (3.62e-3)" 41.7 3.8 2.6 12.8 2.9 0.0 32.5 12.0 3.9 103.6 5.5 159.2 9.3 171.2 14.2 16.2 98.0 16.7 13.7 2.4 3.1 17.1 7.0 18.7 4.5 4.7 2.8 37.0 3.4 0.5 4.1 11.6 3.3 48.3 8.9 0.2 10.8 45.6 5.1 15.2 38.3 59.3 2.8 13.4 44.1 7.3 2.8 0.7 10.7 3.0 1.3 75.2 65.6 2.5 0.0 0.1 0.1 0.0 67.6 30.0 1.4 39.5 99.1 36.8 24.3 0.0 1.8 0.0 0.8 30.8 0.1 0.1 0.1 0.0 6.8 0.0 0.0 0.0 2.8 0.0 8.5 0.0 0.0 22.1 0.0 23.5 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 2.9 1.5 0.8 0.1 0.0 3.4 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 2.5 0.0 0.0 0.0 22.4 0.0 46.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 12.0 3.9 2.4 3.1 4.7 2.8 3.3 2.8 2.8 2.5 3.2 0.0 0.0 0.0 0.6 5.0 0.2 0.0 1.2 0.0 0.3 2.3 0.6 2.8 0.0 11.0 0.0 0.7 0.1 0.0 0.0 0.0 4.9 1.1 20.6 2.3 0.0 0.0 1.1 0.0 0.6 33.3 0.5 0.8 0.0 0.0 3.9 3.8 1.1 0.0 0.2 0.0 0.0 0.0 7.3 7.9 66.2 0.2 7.2 3.7 0.0 3.0 0.0 0.0 0.2 0.1 0.0 100.8 0.1 0.3 0.0 0.9 0.0 0.3 52.6 19.1 63.7 1.3 0.5 0.4 3.8 1.1 0.6 0.6 0.0 0.4 MRO "B29, C18orf3, FLJ30140" ENSG00000134042 Maestro Q9BYG7 18 50795120-50825402 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 44.7;kidney: 24.1;testis: 28.9" "Cell type enhanced" "Detected in some" "Astrocytes: 30.0;Granulosa cells: 11.3;Hepatic stellate cells: 37.5;Kupffer cells: 13.0;Proximal enterocytes: 20.0;Proximal tubular cells: 16.0" "Cancer enriched" "Detected in some" 7 "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC diff: 2.4;ASC TERT1: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022011 Approved NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA022011: AB_2670880" "unprognostic (9.21e-5)" "unprognostic (5.22e-2)" "unprognostic (7.87e-3)" "unprognostic (1.45e-2)" "unprognostic (2.47e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.47e-2)" "unprognostic (5.11e-2)" "unprognostic (3.45e-2)" "unprognostic (2.15e-2)" "unprognostic (1.32e-1)" "unprognostic (4.71e-1)" "unprognostic (5.15e-3)" "unprognostic (1.14e-1)" "unprognostic (3.99e-3)" "unprognostic (6.06e-4)" 2.3 2.5 36.6 0.5 42.7 0.2 0.6 32.5 33.1 0.3 18.4 0.2 8.0 0.2 3.1 0.5 0.3 1.0 3.0 33.3 44.7 24.1 7.2 0.2 0.3 35.9 38.5 3.3 1.8 5.3 1.3 0.7 34.4 0.2 0.2 1.6 0.3 2.2 2.0 0.1 4.7 0.3 33.8 2.2 1.3 28.9 40.8 1.2 6.0 1.3 0.1 0.4 0.2 31.0 0.0 0.0 0.0 0.2 2.4 8.2 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.3 0.1 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 36.6 42.7 32.5 33.1 33.3 44.7 35.9 38.5 34.4 33.8 40.8 31.0 0.2 0.0 0.0 30.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.8 1.5 0.0 0.0 2.1 0.0 0.0 0.2 5.9 0.0 0.8 0.2 0.0 0.9 0.0 0.0 1.5 1.0 0.8 0.8 1.1 0.1 0.0 11.3 37.5 4.7 8.4 0.0 1.1 0.1 0.0 13.0 0.3 3.3 1.2 1.8 0.0 3.7 0.0 3.9 1.0 5.0 0.3 0.1 0.0 0.7 0.0 0.1 20.0 16.0 0.0 0.2 0.0 0.4 0.1 1.2 0.5 0.0 0.0 0.1 0.1 4.3 0.6 0.1 MRPS14 HSMRPS14 ENSG00000120333 "Mitochondrial ribosomal protein S14" O60783 1 175010789-175023425 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051087 Uncertain Supported "Nuclear membrane,Mitochondria" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" Mitochondria "Nuclear membrane" "HPA051087: AB_2681339" "unprognostic (9.24e-2)" "unprognostic (6.37e-2)" "unprognostic (1.50e-1)" "unprognostic (3.46e-1)" "unprognostic (3.44e-2)" "unprognostic (5.39e-2)" "unprognostic (1.61e-2)" "unprognostic (3.01e-2)" "unprognostic (7.32e-2)" "unprognostic (4.85e-2)" "unprognostic (7.67e-2)" "unprognostic (3.10e-2)" "unprognostic (1.31e-3)" "unprognostic (1.67e-1)" "unprognostic (8.04e-2)" "unprognostic (2.42e-1)" "unprognostic (3.21e-2)" 17.2 20.3 24.9 11.2 26.8 4.5 20.6 26.5 28.3 16.2 20.0 13.4 12.4 17.4 21.7 9.5 15.4 13.9 15.1 23.4 26.9 20.4 19.2 13.2 15.8 26.7 25.8 18.4 14.8 28.0 12.2 13.9 26.7 20.2 15.7 22.5 17.0 16.9 13.0 11.4 11.9 14.9 26.6 14.3 14.1 11.2 25.0 17.5 23.2 14.2 15.1 12.0 9.3 28.3 16.2 12.8 29.5 10.5 32.6 23.4 9.4 13.8 16.8 23.0 23.7 16.7 13.9 20.4 16.5 18.6 10.1 14.0 18.5 16.1 24.3 22.6 25.4 16.8 25.6 19.2 13.8 18.9 14.5 25.6 19.4 13.6 9.4 20.3 19.4 17.4 20.7 17.6 16.2 8.9 20.8 13.7 16.2 30.1 6.7 17.8 15.6 24.4 15.8 12.8 24.8 17.4 20.0 18.3 13.8 23.1 21.7 19.7 15.9 7.8 8.6 16.4 12.5 19.1 17.5 25.1 11.1 17.5 16.6 9.3 15.2 7.7 14.8 15.1 21.2 17.5 15.5 15.8 16.2 17.3 20.8 17.6 5.2 18.2 12.3 14.0 19.0 14.3 24.9 26.8 26.5 28.3 23.4 26.9 26.7 25.8 26.7 26.6 25.0 28.3 29.8 28.9 24.5 5.5 38.4 22.0 52.6 105.9 22.2 17.5 31.6 33.8 78.1 44.3 64.0 55.2 14.6 95.4 26.7 26.4 137.0 69.8 23.8 26.5 35.8 39.1 31.8 46.3 7.8 44.8 107.0 41.4 20.4 26.6 18.3 34.8 33.9 67.2 80.7 1.7 9.4 35.8 103.7 34.7 23.9 12.9 46.6 25.6 49.8 9.4 73.9 46.1 45.3 6.6 10.4 47.7 45.7 42.9 48.7 50.0 35.3 126.1 50.6 22.6 39.5 25.1 66.4 96.9 39.1 36.7 29.3 56.1 28.8 43.0 48.8 52.6 MSS51 "FLJ39565, ZMYND17" ENSG00000166343 "MSS51 mitochondrial translational activator" Q4VC12 10 73423579-73433561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 261.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.3;Excitatory neurons: 11.9;Inhibitory neurons: 9.7;Oligodendrocyte precursor cells: 6.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038564 Uncertain Vesicles,Cytosol NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" Vesicles Cytosol "HPA038564: AB_10674687" "unprognostic (2.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.40e-3)" "unprognostic (2.06e-1)" "unprognostic (3.21e-2)" "unprognostic (1.62e-3)" "unprognostic (3.05e-3)" "unprognostic (7.88e-3)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (1.50e-4)" "unprognostic (1.22e-1)" "unprognostic (1.78e-7)" "unprognostic (1.51e-1)" "unprognostic (2.60e-1)" "unprognostic (2.67e-1)" "unprognostic (1.55e-2)" 1.9 1.5 1.5 1.5 1.8 1.6 1.7 4.3 2.0 3.2 1.6 2.3 1.2 2.1 1.7 1.4 2.2 1.2 10.9 1.5 0.6 1.7 1.6 2.2 1.8 0.2 0.3 3.0 1.9 56.2 2.3 0.6 0.2 2.5 1.3 2.5 1.7 0.8 261.3 3.7 2.7 1.1 0.0 3.9 1.8 1.4 0.7 1.5 1.5 5.9 1.5 2.2 2.2 1.3 0.9 0.6 1.5 2.7 2.1 2.8 1.2 0.7 0.5 0.3 0.6 0.3 0.7 2.1 0.2 0.7 0.1 1.1 1.0 0.2 0.8 1.1 0.9 1.7 1.3 0.5 0.7 1.1 1.7 2.4 0.7 0.6 1.7 2.1 0.2 0.8 0.6 1.0 1.2 0.2 0.9 1.6 0.4 0.5 0.7 0.5 4.1 0.1 0.8 0.9 0.3 0.8 0.5 1.0 0.9 1.4 0.9 0.9 1.3 1.2 0.7 0.4 1.7 0.6 2.1 1.1 0.5 1.9 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.8 4.3 2.0 1.5 0.6 0.2 0.3 0.2 0.0 0.7 1.3 0.9 0.0 3.6 4.6 1.0 0.5 0.1 0.6 0.0 1.4 0.4 0.5 5.3 0.0 0.2 0.0 0.0 0.3 0.4 0.4 0.0 0.4 0.3 0.4 0.7 1.2 0.0 1.3 11.9 0.4 0.2 0.8 1.1 0.8 5.1 1.8 1.4 0.2 0.2 0.0 9.7 0.4 0.0 0.8 0.6 0.3 3.1 0.5 0.0 4.7 1.1 0.5 1.0 6.0 3.4 0.2 3.9 1.5 0.4 0.5 0.6 0.2 0.3 1.2 0.0 4.0 0.6 0.7 0.3 0.0 0.0 0.1 1.1 1.4 0.6 0.2 MYH3 "HEMHC, MYHC-EMB, MYHSE1, SMHCE" ENSG00000109063 "Myosin heavy chain 3" P11055 17 10628526-10657309 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 29.0;seminal vesicle: 18.3;skeletal muscle: 20.6" "Cell type enriched" "Detected in many" 7 "Early spermatids: 411.9" "Group enriched" "Detected in many" 4 "head and neck cancer: 3.3;prostate cancer: 4.6;testis cancer: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 26 "HSkMC: 59.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA021808 Enhanced NA NA 29000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA021808: AB_1854242" "unprognostic (1.70e-2)" "unprognostic (1.10e-3)" "unprognostic (4.19e-4)" "unprognostic (3.35e-1)" "unprognostic (7.66e-2)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.28e-1)" "unprognostic (1.67e-2)" "unprognostic (3.54e-1)" "unprognostic (7.84e-4)" "unprognostic (1.29e-1)" "unprognostic (3.24e-4)" "unprognostic (1.91e-2)" "unprognostic (6.17e-3)" "unprognostic (3.40e-2)" "unprognostic (3.49e-1)" 1.6 0.9 1.8 1.1 1.7 0.8 1.5 1.5 1.9 2.9 1.5 7.9 1.1 3.4 1.2 9.1 2.6 0.5 1.0 1.6 1.6 2.1 3.3 1.2 1.3 1.8 1.8 2.3 2.4 0.3 1.5 0.4 1.7 29.0 1.0 1.8 1.5 18.3 20.6 2.8 2.5 1.7 1.4 2.6 1.7 4.6 1.8 3.0 3.4 6.0 0.6 4.4 3.8 1.8 0.2 1.1 0.8 1.1 1.0 0.3 1.0 0.8 0.4 0.5 0.5 1.0 0.1 0.7 0.3 0.4 0.2 1.1 0.5 0.2 1.0 0.7 0.9 1.0 0.3 1.6 0.3 0.6 1.4 59.6 0.4 0.6 0.8 0.1 0.1 1.3 0.4 0.1 0.2 0.7 1.0 2.3 0.9 0.3 0.6 0.8 0.8 0.3 0.3 0.3 0.0 0.4 0.4 0.0 0.3 0.7 0.3 0.3 0.3 0.1 1.0 0.3 0.1 1.3 1.1 0.3 0.3 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.7 1.5 1.9 1.6 1.6 1.8 1.8 1.7 1.4 1.8 1.8 0.5 0.0 9.8 4.6 0.7 2.9 0.9 0.1 0.6 4.9 0.7 1.8 3.6 1.5 0.7 0.0 6.2 0.4 0.8 0.9 0.0 0.6 411.9 0.5 0.8 1.4 0.0 2.7 3.9 0.6 0.8 1.1 1.1 0.5 7.6 0.8 0.4 0.6 0.1 0.0 3.4 0.5 0.0 0.8 0.3 56.0 2.8 1.2 1.8 1.9 0.2 1.8 0.0 7.5 5.4 0.7 0.2 2.6 0.0 1.5 1.8 0.3 0.3 4.6 0.0 5.5 0.8 10.7 4.2 0.3 1.6 0.5 1.4 0.2 0.8 0.3 MYH7 "CMD1S, CMH1, MPD1" ENSG00000092054 "Myosin heavy chain 7" P12883 14 23412740-23435660 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 71 "heart muscle: 7569.2;skeletal muscle: 14554.3;tongue: 5378.8" "Cell type enriched" "Detected in some" 127 "Cardiomyocytes: 10295.8" "Group enriched" "Detected in some" 9 "head and neck cancer: 12.2;prostate cancer: 15.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 31 "HSkMC: 11.4" "Low region specificity" "Detected in many" "HPA001239, HPA001349, CAB015384" Enhanced Uncertain "Focal adhesion sites" NA NA 43000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" "CAB015384: AB_2147279, HPA001239: AB_1079438, HPA001349: AB_1079437" "unprognostic (6.49e-2)" "unprognostic (8.27e-5)" "unprognostic (1.56e-1)" "unprognostic (3.04e-3)" "unprognostic (4.30e-1)" "unprognostic (7.33e-3)" "unprognostic (8.60e-2)" "unprognostic (1.55e-1)" "unprognostic (1.31e-1)" "unprognostic (1.22e-1)" "unprognostic (3.79e-1)" "unprognostic (5.38e-3)" "unprognostic (2.32e-1)" "unprognostic (1.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.28e-2)" 2.0 1.3 1.4 0.0 1.9 0.1 2.5 0.1 1.1 0.3 1.4 1.2 0.5 0.4 0.0 129.2 0.1 1.1 7569.2 1.2 2.9 0.9 1.4 3.2 1.5 0.8 1.6 0.7 7.8 0.0 1.5 0.0 0.9 76.8 0.0 0.0 37.0 0.0 14554.3 4.8 0.9 0.0 0.9 0.5 0.9 1.4 3.2 0.1 1.8 5378.8 0.1 0.2 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.9 0.1 1.1 1.2 2.9 0.8 1.6 0.9 0.9 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10295.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.2 0.0 80.9 0.0 0.0 0.2 3.1 0.0 70.5 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.7 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 3.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 52.2 51.2 0.1 2.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 MYH8 "MyHC-peri, MyHC-pn" ENSG00000133020 "Myosin heavy chain 8" P13535 17 10390322-10421950 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 15.9;lymphoid tissue: 10.7;skeletal muscle: 16.7;tongue: 10.0" "Group enriched" "Detected in some" 8 "Proximal tubular cells: 84.8;Skeletal myocytes: 52.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.7;renal cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "HSkMC: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001349, CAB016527" Enhanced Uncertain "Focal adhesion sites" NA NA 53000000 "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "Focal adhesion sites" "CAB016527: AB_2147291, HPA001349: AB_1079437" "unprognostic (5.87e-2)" "unprognostic (5.13e-3)" "unprognostic (4.12e-2)" "unprognostic (1.25e-2)" "unprognostic (2.29e-3)" "unprognostic (1.08e-1)" "unprognostic (5.02e-3)" "unprognostic (7.87e-2)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.0 16.7 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 10.7 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 3.7 0.0 0.0 0.0 0.0 7.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 84.8 0.0 0.0 0.0 52.0 0.1 0.5 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 MYL1 ENSG00000168530 "Myosin light chain 1" P05976 2 210290150-210315174 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 88 "skeletal muscle: 21805.2;tongue: 15591.3" "Cell type enriched" "Detected in some" 246 "Skeletal myocytes: 492.9" "Group enriched" "Detected in some" 18 "head and neck cancer: 36.0;prostate cancer: 12.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HSkMC: 51.4" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.0" "Low region specificity" "Detected in all" "HPA046859, HPA063034, HPA073827" Enhanced "Intracellular and membrane" NA NA 21000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "HPA046859: AB_2679842, HPA063034: AB_2684927, HPA073827: " "prognostic unfavorable (6.59e-4)" "unprognostic (1.88e-1)" 2.3 0.5 0.1 0.0 0.1 0.0 3.3 0.0 0.1 0.1 0.0 1.1 0.0 0.5 0.0 212.7 0.0 0.0 2.0 0.1 0.0 0.7 1.0 0.9 0.0 0.0 0.0 0.6 1.1 0.0 0.4 0.0 0.0 164.2 0.0 0.0 170.2 0.0 21805.2 4.0 0.7 0.0 0.0 0.4 0.7 0.5 0.0 7.4 2.3 15591.3 0.9 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 11.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 492.9 2.0 0.1 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.1 MYL5 ENSG00000215375 "Myosin light chain 5" Q02045 4 673580-682033 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 66.1" "Cell type enhanced" "Detected in many" "Late spermatids: 87.3;Proximal enterocytes: 55.5;Rod photoreceptor cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 60.4" "Not detected" "Not detected" "HPA037381, HPA039262" Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA037381: AB_10672484, HPA039262: AB_2676418" "unprognostic (6.30e-3)" "unprognostic (1.42e-2)" "unprognostic (5.67e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (5.53e-2)" "unprognostic (1.33e-1)" "unprognostic (4.77e-3)" "unprognostic (2.38e-1)" "unprognostic (8.39e-2)" "unprognostic (1.61e-3)" "unprognostic (1.05e-1)" "unprognostic (2.80e-1)" "unprognostic (2.95e-2)" "unprognostic (3.01e-1)" "unprognostic (1.10e-2)" "unprognostic (1.91e-2)" 17.9 21.4 21.8 7.0 21.8 11.4 16.6 21.9 36.0 10.6 19.4 20.7 20.7 7.4 17.8 20.0 7.9 8.3 10.4 21.0 20.4 19.4 22.2 11.0 11.0 22.8 21.1 7.7 9.9 15.3 13.7 5.1 22.3 18.2 13.0 66.1 13.3 8.9 24.6 18.6 25.2 5.6 20.9 16.1 12.3 22.2 21.9 10.0 13.6 8.3 10.3 11.2 13.3 23.5 4.3 6.9 24.8 13.2 60.4 41.2 11.9 10.2 13.6 10.2 9.3 8.4 17.7 4.9 4.8 16.6 7.3 6.2 4.0 7.0 3.0 9.2 5.0 7.4 11.7 7.9 21.0 11.3 6.5 31.3 6.5 8.1 8.4 14.8 6.3 10.4 7.7 6.5 12.7 8.0 6.1 7.8 5.2 8.8 10.4 5.4 5.3 3.0 16.9 19.9 11.3 6.4 3.4 8.5 7.2 8.0 13.7 10.2 10.4 8.7 1.6 7.5 6.0 24.7 5.3 2.9 9.5 10.1 4.6 15.5 8.2 1.5 3.3 5.5 4.2 8.7 5.6 2.0 7.7 12.7 6.7 6.8 5.8 18.4 12.3 14.5 2.6 5.8 21.8 21.8 21.9 36.0 21.0 20.4 22.8 21.1 22.3 20.9 21.9 23.5 4.5 0.0 11.9 2.3 11.7 12.0 6.8 12.8 18.2 6.3 12.9 14.5 1.4 7.2 5.7 7.3 20.9 7.3 9.2 22.7 11.7 9.6 22.2 9.1 6.9 5.9 5.4 4.2 1.4 4.7 5.4 7.5 13.7 5.3 13.9 4.9 10.4 18.3 22.7 11.8 1.3 11.4 6.1 21.2 8.6 87.3 7.2 12.4 7.2 1.0 22.8 22.2 13.4 0.5 1.6 6.1 13.2 3.8 5.1 8.3 55.5 42.6 8.2 74.3 6.6 21.7 5.6 14.1 4.4 21.2 13.4 5.5 5.9 14.7 15.4 9.7 MYMK "TMEM226, TMEM8C" ENSG00000187616 "Myomaker, myoblast fusion factor" A6NI61 9 133514586-133528612 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Myogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 32 "HSkMC: 15.2;RH-30: 7.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA051846, HPA055785" Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA051846: AB_2681636, HPA055785: AB_2682920" "unprognostic (9.17e-3)" "unprognostic (8.63e-2)" "unprognostic (3.76e-1)" "unprognostic (1.13e-1)" "unprognostic (1.03e-1)" "unprognostic (5.37e-1)" "unprognostic (9.32e-2)" "unprognostic (1.91e-1)" 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.4 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.5 0.2 0.1 0.5 0.2 0.4 0.2 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 NAALADL1 ENSG00000168060 "N-acetylated alpha-linked acidic dipeptidase like 1" Q9UQQ1 11 65044818-65058553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "intestine: 99.3" "Cell type enriched" "Detected in many" 11 "Proximal enterocytes: 588.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 182.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.8;fHDF/TERT166: 7.8;HHSteC: 20.2;HSkMC: 13.5;SCLC-21H: 10.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047123 Enhanced Uncertain Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA047123: AB_2679942" "unprognostic (2.98e-2)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "unprognostic (8.76e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-3)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.75e-4)" "unprognostic (2.10e-3)" "unprognostic (3.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.80e-2)" 13.9 3.2 4.4 6.6 4.1 21.1 12.1 4.7 6.0 23.5 7.0 18.4 19.8 18.8 4.6 7.3 15.2 9.4 10.5 3.9 4.1 7.4 2.6 10.9 10.9 4.7 4.3 16.6 2.3 2.0 6.0 2.3 4.6 13.8 7.1 1.9 4.9 11.5 2.7 5.4 99.3 10.5 4.6 15.3 8.2 8.7 4.4 3.4 5.7 4.1 6.9 12.7 14.5 4.0 0.0 0.0 0.1 0.2 0.5 5.8 1.0 2.3 0.0 2.8 1.3 0.0 0.0 0.1 0.0 7.8 0.0 0.0 0.0 0.2 0.1 0.9 0.4 0.0 0.2 3.5 20.2 0.0 0.0 13.5 0.0 2.7 0.0 0.1 3.6 0.1 0.0 0.3 0.0 0.2 0.2 0.7 0.0 0.1 0.1 0.1 0.0 1.0 0.2 0.0 10.5 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.8 0.0 0.1 0.1 182.0 21.2 35.9 29.6 14.6 15.8 25.7 23.8 14.8 16.3 29.8 27.0 15.0 3.7 80.2 8.8 0.7 45.2 24.6 4.4 4.1 4.7 6.0 3.9 4.1 4.7 4.3 4.6 4.6 4.4 4.0 19.1 0.0 0.0 0.0 8.0 3.6 3.4 5.6 6.2 2.0 0.8 9.1 1.8 1.5 0.4 0.0 0.0 0.2 9.8 31.3 3.9 0.1 0.8 0.4 5.8 11.1 1.2 2.5 0.3 0.8 0.3 11.4 1.1 0.2 19.7 4.3 16.8 0.4 2.8 10.1 0.4 21.0 2.0 5.6 5.7 2.6 11.8 5.2 16.0 1.0 17.3 12.2 41.2 1.0 0.1 0.2 50.0 18.0 1.1 0.5 588.6 0.5 0.5 0.9 0.0 8.3 11.1 1.6 3.5 1.3 3.3 0.4 11.1 3.9 11.8 0.4 NAALADL2 ENSG00000177694 "N-acetylated alpha-linked acidic dipeptidase like 2" Q58DX5 3 174438573-175810548 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 311.5;Inhibitory neurons: 135.1;Microglial cells: 155.5;Oligodendrocyte precursor cells: 468.0;Oligodendrocytes: 532.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 14.5;BJ hTERT+: 5.4;fHDF/TERT166: 6.4;WM-115: 5.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA012413, HPA017425, CAB025586" Approved Enhanced Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "CAB025586: , HPA012413: AB_1854274, HPA017425: AB_1854275" "unprognostic (7.28e-3)" "unprognostic (1.10e-1)" "unprognostic (6.28e-2)" "unprognostic (1.60e-1)" "unprognostic (2.56e-1)" "unprognostic (2.56e-1)" "unprognostic (2.29e-4)" "unprognostic (3.44e-3)" "unprognostic (5.70e-2)" "unprognostic (7.42e-2)" "unprognostic (7.85e-3)" "unprognostic (9.49e-2)" "unprognostic (3.66e-6)" "unprognostic (7.11e-2)" "unprognostic (1.48e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" 2.4 1.1 1.1 1.0 2.3 0.2 5.8 1.2 1.4 6.3 1.1 3.0 1.7 3.7 5.5 1.5 3.8 4.2 2.6 1.4 0.6 3.3 2.9 2.0 0.5 2.2 1.3 3.9 2.2 10.2 0.5 1.2 1.8 4.9 2.4 1.6 5.8 3.7 1.0 0.8 1.6 3.5 1.4 1.9 2.7 0.9 1.5 1.2 2.3 1.7 0.5 3.8 1.2 3.3 0.0 0.0 0.3 0.0 4.4 14.5 0.1 3.1 5.4 0.7 0.9 0.2 1.7 0.0 0.6 6.4 0.2 0.1 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 4.1 0.8 0.1 0.0 3.8 0.5 0.0 0.0 0.1 3.1 0.6 0.2 0.0 0.0 2.2 0.0 0.0 0.2 0.1 2.2 0.3 0.1 0.1 0.3 0.3 1.2 0.3 4.0 0.2 0.7 2.9 0.1 0.1 0.6 0.0 0.0 0.0 1.9 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.1 2.3 1.2 1.4 1.4 0.6 2.2 1.3 1.8 1.4 1.5 3.3 5.1 0.0 11.5 311.5 0.1 2.3 8.9 2.7 1.2 7.7 35.1 13.7 3.0 12.8 9.1 12.9 12.5 19.6 0.3 11.1 7.9 10.1 74.9 23.7 8.7 2.8 9.0 2.7 113.4 2.5 1.4 15.0 23.9 30.2 4.5 3.4 2.9 4.5 1.8 0.0 135.1 2.6 10.2 0.3 3.0 39.6 15.2 1.1 3.6 155.5 0.0 6.7 0.0 468.0 532.9 3.6 4.4 12.0 0.0 13.6 13.2 2.4 21.9 6.2 0.0 23.4 4.9 3.2 2.8 5.3 1.8 12.3 0.8 5.7 16.4 16.0 NAGLU NAG ENSG00000108784 N-acetyl-alpha-glucosaminidase P54802 17 42536241-42544449 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Charcot-Marie-Tooth disease, Disease variant, Mucopolysaccharidosis, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038815 Supported "Intracellular and membrane" NA NA 270000000 "Cluster 37: B-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA038815: AB_10697398" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (6.48e-2)" "prognostic favorable (4.17e-4)" "prognostic unfavorable (6.59e-4)" "unprognostic (1.46e-1)" "unprognostic (1.75e-3)" "unprognostic (3.09e-2)" "unprognostic (2.20e-1)" "unprognostic (6.68e-2)" "prognostic favorable (6.90e-4)" "unprognostic (8.07e-2)" "prognostic favorable (2.58e-6)" "unprognostic (2.25e-1)" "unprognostic (8.74e-3)" "unprognostic (2.15e-2)" "unprognostic (1.62e-1)" 41.6 37.9 12.5 14.8 21.6 20.3 35.3 16.6 16.7 31.1 28.7 25.1 24.3 34.7 12.8 19.5 27.6 27.4 20.1 12.0 15.0 39.3 59.3 30.8 24.0 18.0 19.2 35.2 63.8 21.3 22.5 26.1 20.1 28.3 16.4 3.1 37.7 18.4 16.0 25.1 30.9 13.8 14.2 40.7 35.1 8.7 19.5 17.1 37.6 9.7 13.4 28.9 23.9 30.0 16.0 55.3 10.8 24.6 106.6 34.5 36.4 24.0 56.9 24.9 31.7 14.9 40.4 20.3 23.7 37.4 54.7 38.3 9.7 11.7 5.5 15.8 20.2 11.2 31.3 31.8 35.3 13.3 27.7 41.4 17.8 13.6 16.9 27.3 32.8 3.6 16.6 39.3 27.9 38.9 2.2 23.0 12.6 34.6 7.0 8.7 23.6 47.2 33.1 36.1 16.2 24.4 12.9 17.6 20.4 15.6 82.1 14.1 25.8 59.3 9.7 23.8 15.7 52.6 25.8 17.6 35.9 14.4 43.1 1.1 2.4 1.9 2.5 1.8 2.4 2.4 1.0 1.3 2.1 1.8 1.8 1.4 1.1 2.1 2.9 2.8 0.2 1.1 12.5 21.6 16.6 16.7 12.0 15.0 18.0 19.2 20.1 14.2 19.5 30.0 14.1 12.8 7.8 17.3 9.0 2.8 6.1 3.9 2.2 15.5 14.2 8.9 3.8 18.6 4.9 18.4 4.2 23.8 11.4 21.1 3.9 18.4 0.3 5.8 14.5 12.2 6.7 4.4 2.3 33.2 14.5 26.4 27.0 12.1 2.5 40.1 24.3 43.7 37.6 15.2 3.1 17.6 0.0 26.0 3.5 2.4 19.9 19.0 16.0 10.3 5.9 13.2 8.2 6.0 19.2 15.8 5.4 12.8 12.9 10.7 23.0 31.8 3.7 6.7 6.6 18.0 12.8 0.4 6.0 6.1 3.4 18.5 6.0 74.6 15.0 6.0 NCSTN "APH2, KIAA0253" ENSG00000162736 Nicastrin Q92542 1 160343316-160358952 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021982, HPA054846, HPA070642" Approved Approved Cytosol NA NA 130000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB021982: , HPA054846: AB_2682624, HPA070642: AB_2686289" "unprognostic (1.08e-1)" "unprognostic (5.22e-3)" "unprognostic (1.51e-1)" "unprognostic (2.89e-2)" "unprognostic (1.19e-2)" "unprognostic (2.22e-2)" "unprognostic (1.69e-3)" "unprognostic (2.89e-1)" "unprognostic (3.30e-2)" "unprognostic (3.62e-2)" "unprognostic (8.21e-2)" "unprognostic (2.06e-2)" "prognostic unfavorable (7.75e-9)" "unprognostic (1.36e-3)" "unprognostic (3.15e-1)" "unprognostic (3.14e-2)" "unprognostic (4.89e-2)" 51.0 36.6 30.6 42.1 36.1 38.1 43.9 38.5 32.5 52.4 42.0 58.4 80.4 40.3 56.4 35.1 49.7 42.9 50.6 29.9 35.8 59.7 59.3 56.0 38.3 40.0 34.0 51.7 63.8 86.0 30.1 98.7 41.6 45.2 60.9 48.1 60.5 47.3 37.6 38.9 63.5 52.1 37.3 46.2 45.7 41.8 36.4 40.0 63.8 38.4 43.0 45.6 31.5 48.9 52.1 57.4 100.4 82.8 301.0 153.4 108.3 104.0 177.0 95.4 109.9 47.9 140.0 36.6 208.6 209.3 67.1 81.5 47.3 95.9 82.4 56.5 42.3 36.6 70.9 70.0 118.6 82.8 152.0 155.7 92.3 94.3 93.6 207.2 139.9 54.3 66.9 100.2 142.2 34.3 26.8 39.8 82.2 130.6 33.8 35.1 59.9 103.6 130.5 69.9 34.2 75.6 109.1 118.5 70.9 158.0 108.2 186.3 125.5 70.3 46.4 48.8 79.9 130.8 194.4 38.6 106.6 49.8 129.4 71.4 79.0 67.8 27.4 79.0 26.2 31.1 23.5 24.0 75.1 27.8 23.9 23.3 69.2 36.6 79.6 45.1 26.5 52.2 30.6 36.1 38.5 32.5 29.9 35.8 40.0 34.0 41.6 37.3 36.4 48.9 28.0 6.4 9.3 0.0 23.0 10.5 23.8 59.5 15.9 20.0 27.9 23.1 14.6 45.8 42.6 53.3 52.1 107.7 27.8 53.3 7.9 38.9 2.6 19.2 19.7 23.9 20.3 17.2 0.0 27.0 95.7 33.7 17.9 30.2 13.3 25.8 29.6 31.4 58.0 18.5 0.0 31.8 46.8 47.1 18.8 4.7 27.1 33.4 17.8 0.0 31.7 35.0 20.6 0.0 0.0 34.8 33.4 21.1 33.2 15.6 66.1 24.7 28.7 26.3 26.3 23.8 19.6 44.6 35.9 15.5 11.4 147.4 16.5 32.5 29.6 20.5 NDN "HsT16328, PWCR" ENSG00000182636 "Necdin, MAGE family member" Q99608 15 23685400-23687305 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 236.4;Peritubular cells: 207.6;Theca cells: 121.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 55.0;ASC diff: 52.9;HSkMC: 71.3;NTERA-2: 44.0;SuSa: 57.4;U-2 OS: 80.4;U-266/70: 51.7;U-266/84: 51.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074457 Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA074457: AB_2686691" "unprognostic (3.49e-1)" "unprognostic (1.65e-1)" "unprognostic (4.20e-1)" "unprognostic (2.19e-2)" "unprognostic (2.71e-1)" "unprognostic (9.04e-2)" "unprognostic (6.79e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.52e-4)" "unprognostic (1.89e-2)" "unprognostic (8.10e-2)" "unprognostic (1.96e-1)" "unprognostic (6.81e-2)" 46.8 49.4 43.3 11.1 40.5 1.2 35.1 26.0 39.7 70.5 30.4 35.9 11.1 63.7 24.0 16.8 47.2 23.8 34.6 36.7 89.6 13.0 4.5 19.6 10.9 36.0 41.3 69.8 11.8 8.7 56.3 32.6 46.2 27.3 10.7 20.8 12.7 39.3 14.7 11.9 20.8 33.5 36.7 19.1 20.3 18.5 69.6 6.8 17.4 22.4 6.6 31.4 40.4 32.3 0.1 0.0 55.0 0.0 52.9 20.1 0.1 35.4 0.0 0.8 9.6 0.0 0.0 0.0 0.1 10.6 8.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.3 0.0 31.8 71.3 0.0 10.2 0.0 0.0 0.0 21.7 1.2 0.0 18.0 0.0 27.6 0.1 44.0 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.1 0.4 0.0 0.4 0.0 57.4 9.4 0.0 0.0 2.6 80.4 0.0 0.1 51.7 51.7 0.0 5.5 0.0 0.4 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 1.5 0.0 0.0 43.3 40.5 26.0 39.7 36.7 89.6 36.0 41.3 46.2 36.7 69.6 32.3 24.1 25.6 11.0 6.8 0.3 13.0 13.8 0.3 27.9 66.0 2.3 19.8 36.8 15.7 1.4 12.9 20.9 1.9 2.9 18.5 23.5 17.9 2.5 1.4 60.8 18.7 6.7 4.2 7.8 10.7 1.4 103.1 4.1 1.1 0.0 83.9 38.9 0.2 7.3 50.5 21.8 4.3 0.0 7.6 13.3 8.6 236.4 2.8 39.2 9.4 0.7 88.7 0.0 9.5 16.4 4.5 2.6 207.6 0.0 6.9 8.1 1.1 4.1 51.0 98.6 91.4 94.0 28.5 21.8 13.4 8.2 2.5 1.4 121.8 7.1 4.1 NEK9 "DKFZp434D0935, MGC16714, Nek8, NERCC, NERCC1" ENSG00000119638 "NIMA related kinase 9" Q8TD19 14 75079353-75127344 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001405 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "HPA001405: AB_1079467" "unprognostic (1.00e-1)" "unprognostic (5.37e-2)" "unprognostic (9.97e-3)" "unprognostic (2.64e-2)" "unprognostic (3.86e-1)" "unprognostic (2.77e-1)" "unprognostic (1.12e-1)" "unprognostic (5.60e-3)" "unprognostic (2.81e-1)" "unprognostic (1.15e-1)" "prognostic favorable (5.63e-4)" "unprognostic (8.58e-2)" "unprognostic (1.36e-2)" "unprognostic (4.54e-2)" "unprognostic (9.22e-2)" "unprognostic (2.61e-1)" "unprognostic (1.57e-2)" 24.2 18.5 6.7 18.6 8.4 11.8 17.3 7.5 7.9 24.3 9.0 14.3 15.5 26.0 10.5 17.8 25.2 17.9 37.2 6.1 7.8 18.4 21.0 18.8 21.0 8.2 7.7 35.8 16.0 34.2 3.1 21.2 7.9 23.5 16.3 16.5 12.4 28.1 43.6 8.1 16.9 32.2 7.5 19.7 13.1 20.4 7.7 28.3 19.7 36.9 23.5 16.3 2.9 9.1 21.3 30.8 44.8 45.4 86.3 88.8 37.9 32.4 54.6 29.7 29.4 25.5 24.7 52.7 0.1 54.2 23.1 31.8 45.0 27.0 38.5 38.2 16.8 23.0 27.3 17.3 48.6 10.8 26.8 76.6 32.8 31.8 26.7 71.6 46.1 36.2 23.8 31.4 40.2 4.8 35.5 11.5 21.9 43.3 18.8 53.5 49.4 23.9 21.3 28.2 19.5 41.3 39.5 19.3 30.0 50.4 41.7 37.6 46.3 30.2 12.7 31.5 15.8 34.3 36.5 49.6 24.9 24.8 26.4 3.4 3.5 3.1 2.5 3.4 4.0 1.3 2.4 2.3 5.0 1.9 3.1 2.8 1.2 3.3 2.5 1.1 1.5 2.9 6.7 8.4 7.5 7.9 6.1 7.8 8.2 7.7 7.9 7.5 7.7 9.1 15.3 12.8 30.2 49.3 21.2 8.8 7.7 6.6 21.1 16.8 14.5 12.4 55.7 12.8 14.8 11.0 35.5 17.4 11.1 10.2 7.9 6.9 11.9 13.3 23.1 17.6 5.4 16.2 31.3 4.9 16.2 18.1 10.7 10.4 16.4 36.8 17.9 30.3 13.9 13.5 35.9 10.7 6.1 18.6 11.8 8.3 24.8 17.0 3.6 30.9 16.0 12.0 15.5 41.2 59.5 5.3 11.7 26.4 14.7 7.4 13.1 8.4 17.4 23.1 0.0 18.9 16.7 28.8 13.9 17.4 10.2 14.0 16.5 20.8 10.5 5.6 NID1 "entactin, NID" ENSG00000116962 "Nidogen 1" P14543 1 235975830-236065109 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 230.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 362.9;Fibroblasts: 137.6;Hepatic stellate cells: 191.3;Leydig cells: 177.3;Peritubular cells: 125.6;Sertoli cells: 243.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 5.7;intermediate monocyte: 11.2;myeloid DC: 4.4;non-classical monocyte: 7.3" "Group enriched" "Detected in many" 18 "dendritic cells: 4.4;monocytes: 11.2" "Cell line enhanced" "Detected in many" "ASC diff: 1569.3;ASC TERT1: 726.8;HSkMC: 619.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010044 Approved "Secreted to extracellular matrix" NA NA 150000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "CAB010044: AB_2153287" "unprognostic (1.17e-1)" "unprognostic (2.23e-3)" "unprognostic (3.24e-1)" "unprognostic (2.35e-1)" "unprognostic (4.03e-1)" "unprognostic (2.79e-2)" "unprognostic (2.44e-3)" "unprognostic (1.42e-2)" "unprognostic (7.88e-2)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (5.38e-8)" "unprognostic (3.64e-3)" "unprognostic (1.35e-1)" "unprognostic (7.36e-2)" "unprognostic (3.72e-3)" 110.0 35.5 4.1 30.5 6.8 2.6 88.9 3.4 7.4 78.9 8.8 95.9 21.7 87.6 21.3 26.8 88.1 66.2 53.7 3.8 4.3 28.4 76.9 56.4 12.3 4.2 4.0 77.7 18.3 12.6 10.4 230.9 3.9 33.1 21.3 2.0 17.3 40.2 25.1 24.6 61.0 79.8 3.9 38.0 67.0 6.2 5.3 5.4 27.6 26.9 6.1 62.9 53.4 3.8 1.2 5.3 55.3 0.1 1569.3 726.8 106.2 128.1 105.3 78.0 50.7 30.5 39.8 0.0 25.0 191.2 21.3 4.5 36.3 0.4 45.2 0.2 61.3 8.1 5.9 46.3 295.6 0.0 0.7 619.5 5.3 38.2 1.5 30.3 165.7 0.0 0.0 0.0 26.9 0.0 0.1 0.3 56.9 0.0 6.7 0.0 0.1 0.1 0.0 16.6 0.3 47.0 1.0 0.0 10.2 21.3 0.1 52.1 146.5 67.5 44.8 0.1 57.4 0.1 0.0 0.1 0.8 0.0 105.4 0.2 5.7 0.0 0.0 11.2 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.4 0.1 7.3 0.0 0.0 2.1 4.1 6.8 3.4 7.4 3.8 4.3 4.2 4.0 3.9 3.9 5.3 3.8 48.7 3.2 1.5 18.9 1.7 6.0 1.3 1.5 0.0 0.2 1.2 2.0 24.0 10.0 2.0 0.0 0.0 13.5 0.6 0.0 0.0 0.5 1.4 11.5 362.9 49.4 0.0 5.3 0.6 0.9 10.2 137.6 0.5 9.6 1.3 2.1 191.3 73.4 8.0 3.3 3.3 0.0 10.2 15.1 19.3 5.7 177.3 9.9 17.8 30.0 10.0 2.2 1.0 1.0 0.3 4.3 0.0 125.6 0.0 5.3 0.0 8.6 0.1 0.1 243.3 18.7 92.3 0.8 0.2 0.8 5.3 15.7 2.9 5.7 0.1 7.3 NID2 ENSG00000087303 "Nidogen 2" Q14112 14 52004803-52069228 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 60.8" "Cell type enhanced" "Detected in many" "Adipocytes: 31.0;Endothelial cells: 19.7;Fibroblasts: 46.0;Microglial cells: 19.7;Smooth muscle cells: 22.6;Theca cells: 19.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 285.4;ASC TERT1: 113.0;BJ: 152.1;BJ hTERT+: 131.8;HHSteC: 158.1;HSkMC: 591.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052460, HPA058772" Enhanced Enhanced "Plasma membrane" "Secreted to extracellular matrix" NA NA 6300000 "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA052460: AB_2681840, HPA058772: AB_2683815" "unprognostic (6.51e-2)" "unprognostic (3.55e-3)" "unprognostic (3.73e-2)" "unprognostic (3.25e-2)" "unprognostic (2.04e-1)" "unprognostic (1.94e-1)" "unprognostic (5.37e-2)" "unprognostic (3.05e-3)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (4.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.48e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (4.58e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (2.78e-4)" 28.3 5.2 0.9 9.2 1.2 0.7 9.6 0.6 1.4 7.5 44.0 8.8 2.3 17.4 5.8 5.4 6.7 19.0 15.6 1.4 0.5 4.8 5.9 6.1 3.5 1.8 0.6 18.9 3.4 13.2 2.5 60.8 0.5 8.4 6.8 0.1 3.6 10.4 4.3 1.7 3.5 11.4 1.1 1.9 6.8 1.4 0.9 2.1 31.6 5.5 1.4 15.4 5.4 1.6 0.0 3.4 76.6 0.0 285.4 113.0 0.2 152.1 131.8 14.5 15.0 0.4 0.0 0.0 22.2 17.3 0.0 10.7 9.9 0.1 3.9 0.1 2.0 0.0 3.0 0.0 158.1 0.0 0.0 591.5 0.0 59.6 0.1 82.5 8.1 0.1 0.0 0.0 8.6 0.0 0.0 0.4 3.3 0.0 5.1 23.5 0.2 0.1 19.9 0.0 0.0 1.8 0.0 0.1 0.0 10.0 0.0 0.0 0.9 54.4 0.6 33.0 0.0 0.0 0.0 0.1 17.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.2 0.6 1.4 1.4 0.5 1.8 0.6 0.5 1.1 0.9 1.6 31.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.6 1.4 0.2 0.3 2.1 0.0 0.0 1.8 0.0 0.7 0.7 3.7 0.0 0.1 14.0 1.5 11.3 19.7 0.0 0.0 0.8 0.0 1.1 46.0 1.1 0.4 1.3 0.4 8.6 0.0 1.6 0.0 1.7 2.0 0.0 0.3 1.2 4.4 6.2 0.3 3.6 19.7 1.0 0.0 0.0 2.0 4.8 0.2 1.3 8.6 0.1 0.2 1.7 0.4 0.0 0.8 6.6 6.1 22.6 0.2 0.1 0.1 1.0 0.8 0.4 19.1 3.0 0.2 NIPAL2 "FLJ13955, NPAL2" ENSG00000104361 "NIPA like domain containing 2" Q9H841 8 98189826-98294393 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 124.5;Squamous epithelial cells: 57.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 45.5;OE19: 38.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071759 Uncertain NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071759: AB_2686443" "unprognostic (5.14e-3)" "unprognostic (6.43e-2)" "unprognostic (8.01e-2)" "unprognostic (2.02e-1)" "unprognostic (4.52e-2)" "unprognostic (5.18e-2)" "unprognostic (3.72e-1)" "unprognostic (9.45e-2)" "unprognostic (1.90e-2)" "unprognostic (3.67e-1)" "unprognostic (3.42e-1)" "unprognostic (2.41e-1)" "unprognostic (2.18e-3)" "unprognostic (1.28e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-1)" "unprognostic (4.76e-2)" 12.6 12.5 6.1 7.8 6.6 6.4 17.7 4.2 13.5 22.9 5.2 17.8 9.2 14.5 41.0 30.1 12.2 15.4 8.6 7.7 5.1 5.9 7.8 10.3 8.6 3.7 3.5 27.5 16.8 11.7 21.9 8.5 3.8 22.9 24.1 11.7 20.6 15.9 2.3 53.2 11.7 7.8 5.0 8.1 19.7 4.9 4.3 3.4 7.2 2.6 13.0 13.2 21.8 8.8 7.9 3.1 1.0 0.1 45.5 27.5 0.2 13.9 17.6 2.5 3.4 0.0 22.7 14.7 15.7 19.5 3.7 9.2 0.7 8.3 1.9 1.3 2.8 5.4 2.1 1.1 5.8 5.7 5.5 28.4 21.6 2.6 7.6 1.4 3.2 0.1 0.0 29.1 10.2 10.9 0.2 3.1 1.8 38.1 1.1 0.0 0.2 1.7 9.1 17.7 1.5 3.0 10.1 8.6 3.5 1.2 9.2 10.5 9.2 1.9 0.2 7.0 0.1 0.3 0.0 0.1 3.4 18.2 9.5 0.1 2.0 2.9 0.7 1.9 0.0 1.7 0.6 0.6 3.7 2.6 0.0 0.5 0.3 1.7 1.6 1.5 2.0 1.6 6.1 6.6 4.2 13.5 7.7 5.1 3.7 3.5 3.8 5.0 4.3 8.8 6.1 3.2 9.3 3.6 11.0 15.3 8.4 19.2 22.8 16.5 10.4 10.8 5.2 7.2 15.8 3.7 2.1 0.2 3.0 20.6 0.0 8.2 7.3 4.6 21.1 8.0 7.2 11.2 124.5 12.8 1.1 13.2 30.5 5.4 5.7 4.1 8.6 3.6 4.6 21.9 30.5 26.3 6.1 6.8 9.4 4.0 25.7 8.5 3.6 26.2 6.0 9.7 10.3 10.6 3.4 9.4 11.0 23.0 6.6 13.4 8.6 1.2 14.3 2.6 6.6 3.3 6.8 0.8 0.7 57.3 22.9 0.3 3.0 12.4 17.2 22.7 NKAPL "bA424I5.1, C6orf194" ENSG00000189134 "NFKB activating protein like" Q5M9Q1 6 28259297-28260958 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 12.6;testis: 32.3" "Group enriched" "Detected in many" 4 "Early spermatids: 401.2;Spermatocytes: 307.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 3.2;BJ: 1.4;fHDF/TERT166: 2.2;HHSteC: 4.6;HSkMC: 3.0;HUVEC TERT2: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (3.93e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-2)" "unprognostic (9.73e-2)" "unprognostic (2.47e-1)" "unprognostic (7.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.88e-2)" "unprognostic (3.84e-3)" "unprognostic (5.78e-2)" "unprognostic (5.83e-5)" "unprognostic (6.65e-3)" "unprognostic (2.38e-1)" "unprognostic (2.08e-2)" "unprognostic (2.47e-2)" 1.9 1.3 5.9 0.7 5.9 0.2 1.5 6.4 9.0 0.8 5.0 2.2 0.2 1.1 1.1 0.9 0.7 0.7 5.0 5.6 6.1 2.0 0.8 0.7 0.7 6.8 6.3 2.0 1.5 0.3 2.1 0.8 6.7 1.4 0.4 12.6 1.6 2.5 5.6 0.7 0.7 1.4 6.1 1.3 1.1 32.3 6.4 0.5 1.0 4.0 0.5 2.0 0.5 6.6 0.0 0.0 0.0 0.0 3.2 0.9 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 3.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 1.6 0.1 1.3 0.3 1.2 0.0 0.2 0.9 0.1 0.2 0.2 2.2 0.3 1.0 2.5 0.0 0.2 5.9 5.9 6.4 9.0 5.6 6.1 6.8 6.3 6.7 6.1 6.4 6.6 4.2 0.0 0.0 2.6 1.1 1.0 1.6 2.5 0.0 29.5 1.8 3.7 13.0 1.5 2.6 1.8 43.8 0.1 4.7 0.0 9.8 2.1 401.2 0.4 2.5 4.8 0.0 0.0 3.3 0.7 0.0 4.1 0.0 0.2 0.0 1.4 3.9 3.5 3.2 33.7 3.3 0.1 10.2 5.1 3.1 49.2 5.6 2.7 5.4 1.9 3.6 15.7 2.1 1.0 2.1 1.4 0.0 6.4 0.4 1.6 0.1 4.1 1.3 77.4 0.0 3.1 5.7 307.1 28.1 1.1 0.9 0.3 1.9 3.2 0.1 0.6 NNT ENSG00000112992 "Nicotinamide nucleotide transhydrogenase" Q13423 5 43602692-43707405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 239.1;tongue: 384.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 344.3;Hepatocytes: 314.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004829, CAB004975" Enhanced Approved Mitochondria,Cytosol NA NA 110000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Cytosol "CAB004975: AB_425908, HPA004829: AB_1079495" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (4.81e-2)" "unprognostic (5.02e-2)" "unprognostic (1.81e-1)" "unprognostic (4.04e-2)" "unprognostic (1.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.98e-2)" "unprognostic (1.65e-1)" "unprognostic (8.33e-2)" "prognostic favorable (1.22e-15)" "unprognostic (8.24e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (2.58e-1)" 26.0 16.5 12.8 11.8 16.0 15.0 13.7 11.2 21.7 16.4 34.9 25.9 17.2 11.0 16.7 16.8 10.7 15.0 137.7 16.1 11.5 57.0 116.4 13.2 16.5 10.3 12.0 10.1 17.8 55.6 9.6 12.7 9.5 18.3 27.8 12.9 26.6 18.2 239.1 10.4 16.1 20.6 9.3 11.5 31.2 6.2 15.8 26.8 31.1 384.0 17.2 17.3 9.3 15.1 15.4 12.6 30.5 59.6 44.0 50.3 9.9 17.5 39.8 24.8 20.8 19.0 30.4 18.5 21.5 43.9 22.3 16.6 120.5 5.4 27.4 31.1 33.6 24.0 70.7 23.8 27.5 50.2 43.1 37.9 17.5 16.3 18.6 42.6 56.3 22.7 21.4 81.3 60.0 15.1 55.8 35.8 6.4 0.1 15.2 54.7 73.8 70.8 58.0 15.5 44.2 37.7 62.9 1.4 46.7 6.9 47.7 58.3 23.2 29.5 28.3 12.0 8.3 36.1 45.1 26.5 7.1 68.8 22.1 12.5 18.2 16.0 16.7 23.0 17.1 12.0 17.1 15.5 32.0 12.0 15.5 14.7 2.9 23.2 24.7 9.1 22.2 19.3 12.8 16.0 11.2 21.7 16.1 11.5 10.3 12.0 9.5 9.3 15.8 15.1 12.0 54.5 37.8 60.7 19.6 11.5 9.5 19.0 13.1 17.9 9.6 6.3 344.3 38.6 27.0 27.6 35.5 8.7 20.4 34.4 27.4 14.4 16.7 18.5 16.6 19.2 19.9 34.9 124.8 10.7 2.3 27.2 23.9 25.1 25.2 26.8 21.0 314.3 25.0 6.7 110.6 22.6 20.3 40.6 11.9 4.6 14.9 19.8 14.2 45.9 25.9 12.5 35.0 77.9 63.4 9.5 16.7 19.2 20.0 11.7 23.6 21.7 18.1 12.8 0.0 14.0 20.1 4.0 1.4 17.6 8.1 2.1 20.9 18.8 28.9 9.9 NOVA1 NOVA-1 ENSG00000139910 "NOVA alternative splicing regulator 1" P51513 14 26443090-26598033 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 222.9;Excitatory neurons: 414.9;Oligodendrocyte precursor cells: 1269.7;Oligodendrocytes: 319.5" "Cancer enriched" "Detected in many" 5 "glioma: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 53.3;ASC diff: 25.6;HAP1: 23.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004155 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Nucleoplasm "HPA004155: AB_1079497" "unprognostic (1.46e-1)" "unprognostic (4.43e-3)" "unprognostic (6.55e-3)" "unprognostic (4.00e-2)" "unprognostic (6.69e-3)" "unprognostic (4.29e-2)" "unprognostic (3.74e-3)" "unprognostic (2.41e-1)" "unprognostic (5.21e-1)" "unprognostic (4.32e-2)" "unprognostic (5.04e-4)" "unprognostic (2.40e-1)" "unprognostic (1.93e-3)" "unprognostic (9.27e-4)" "unprognostic (9.20e-2)" "unprognostic (5.62e-2)" "unprognostic (1.31e-4)" 23.4 5.4 44.0 2.4 39.7 0.1 28.9 85.4 56.3 12.1 18.9 11.6 1.4 8.5 4.9 2.9 6.7 4.8 3.3 38.8 65.3 6.1 0.9 1.4 3.4 50.3 51.2 5.0 1.2 2.4 19.3 0.1 48.5 5.6 5.1 13.4 2.7 15.9 4.3 4.7 3.6 9.5 49.2 0.9 3.3 8.8 71.1 1.2 3.4 8.7 4.5 5.9 8.4 45.5 0.0 11.6 53.3 0.0 25.6 14.6 0.1 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.7 0.7 7.1 0.1 23.7 0.2 0.0 0.0 1.8 0.0 0.1 0.3 8.5 0.0 2.1 16.8 0.0 3.6 2.9 17.8 10.3 8.7 0.0 0.1 8.4 0.0 9.8 0.1 13.5 0.0 10.9 1.3 14.8 0.2 6.8 9.1 15.5 9.4 0.0 0.0 0.0 4.2 1.1 0.0 0.0 6.5 7.7 5.2 1.4 0.0 0.0 0.0 8.8 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 44.0 39.7 85.4 56.3 38.8 65.3 50.3 51.2 48.5 49.2 71.1 45.5 24.8 0.0 1.5 141.0 0.2 5.2 5.9 0.0 4.6 222.9 51.5 29.6 1.1 5.7 0.0 14.7 4.2 0.1 1.4 6.6 9.8 0.4 20.1 0.6 15.0 9.4 65.9 0.0 414.9 0.4 0.0 188.8 0.5 0.2 0.0 18.2 38.6 0.5 0.2 136.3 203.5 7.1 0.0 0.6 10.5 16.5 150.4 2.1 3.6 93.7 0.0 32.3 0.0 1269.7 319.5 2.0 11.7 65.8 1.9 6.7 0.3 30.3 4.4 12.0 6.6 28.6 17.7 163.1 64.3 0.7 3.1 0.0 1.5 30.0 8.4 0.6 NPC2 "EDDM1, HE1, NP-C2" ENSG00000119655 "NPC intracellular cholesterol transporter 2" P61916 14 74476192-74494177 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "epididymis: 16783.1" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 2034.2;Hofbauer cells: 2898.5;Kupffer cells: 2035.4" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 769.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 668.7;classical monocyte: 1300.7;intermediate monocyte: 1772.7;myeloid DC: 587.8;neutrophil: 674.2;non-classical monocyte: 1252.1;plasmacytoid DC: 2113.2" "Group enriched" "Detected in all" 5 "dendritic cells: 2113.2;granulocytes: 674.2;monocytes: 1772.7" "Cell line enhanced" "Detected in all" "ASC diff: 1619.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000835, CAB032888" Enhanced "Secreted to blood" NA NA 53000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032888: AB_2157036, HPA000835: AB_1079499" "unprognostic (1.27e-3)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.83e-5)" "unprognostic (1.17e-1)" "unprognostic (1.82e-2)" "unprognostic (3.72e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (6.67e-3)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.32e-1)" "unprognostic (3.11e-3)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.97e-1)" "prognostic favorable (6.55e-4)" "unprognostic (1.42e-1)" 260.1 297.0 127.1 261.3 145.4 305.3 221.3 152.2 190.6 284.5 434.0 259.7 201.7 196.7 16783.1 185.0 170.0 356.0 215.1 118.1 156.9 322.4 202.4 786.0 360.3 185.7 145.6 283.1 219.9 241.3 197.5 263.1 179.2 164.2 220.8 48.6 221.9 261.3 58.7 181.6 193.3 180.5 151.1 305.6 206.8 156.8 172.1 134.4 444.7 114.7 241.9 347.4 187.9 195.5 297.2 199.3 124.8 179.4 1619.3 498.6 404.8 194.1 707.1 200.9 398.9 351.7 420.3 78.6 141.6 181.9 372.6 595.9 170.0 405.5 188.6 120.4 126.3 29.6 96.7 296.2 348.6 51.0 548.4 467.7 388.9 173.7 336.9 930.2 298.1 87.0 32.9 601.4 224.0 106.9 70.1 75.9 52.9 489.0 307.9 39.5 219.1 281.6 511.1 735.0 5.5 91.3 296.3 120.3 298.0 359.6 205.2 225.7 268.9 291.9 342.0 396.1 188.2 253.7 452.5 24.2 292.1 168.4 163.4 668.7 1300.7 274.1 92.2 1772.7 87.9 295.2 126.5 92.3 587.8 241.8 120.9 100.5 674.2 99.5 1252.1 2113.2 187.8 1304.5 127.1 145.4 152.2 190.6 118.1 156.9 185.7 145.6 179.2 151.1 172.1 195.5 154.9 381.4 2034.2 11.1 160.2 374.9 557.8 1074.2 170.2 9.9 138.6 220.5 55.4 163.0 626.9 331.1 22.9 228.3 664.0 301.0 305.2 500.4 90.9 123.8 168.5 276.5 119.7 65.4 2.1 279.4 803.3 318.1 61.7 161.0 341.4 104.2 447.3 195.6 2898.5 8.4 3.8 264.8 832.1 2035.4 750.9 69.6 566.7 1462.6 602.9 6.5 790.5 167.4 117.4 7.5 24.4 368.3 405.1 291.9 287.4 357.9 298.1 969.0 393.3 25.1 131.5 118.3 155.9 268.1 166.7 182.6 320.7 210.4 109.9 330.0 298.5 521.6 NPIPA5 ENSG00000183793 "Nuclear pore complex interacting protein family member A5" E9PKD4 16 15363628-15381047 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 20.4;granulocytes: 11.4;Respiratory ciliated cells: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "THP-1: 17.7" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (1.20e-1)" "unprognostic (1.52e-2)" "unprognostic (1.94e-2)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (4.19e-4)" "unprognostic (5.85e-2)" "unprognostic (5.92e-2)" "unprognostic (7.85e-2)" "unprognostic (6.58e-2)" "unprognostic (9.02e-3)" "unprognostic (1.57e-2)" "unprognostic (4.34e-3)" "unprognostic (1.85e-1)" "unprognostic (2.85e-1)" "unprognostic (9.18e-2)" "unprognostic (4.02e-2)" 26.3 24.4 21.7 1.2 22.1 4.1 22.9 27.7 26.3 29.9 16.7 43.1 2.8 32.8 8.3 21.3 18.1 5.1 23.5 22.3 22.7 36.8 22.0 21.9 3.1 23.1 21.7 43.0 28.1 4.8 78.3 1.4 22.9 32.4 2.7 10.8 18.7 2.9 33.9 26.8 24.6 2.7 18.7 28.8 26.0 42.8 21.0 5.4 28.8 4.1 1.5 25.8 23.7 21.5 1.1 1.5 5.4 0.8 9.9 10.3 0.8 2.1 5.0 6.9 7.0 2.3 1.0 2.3 0.6 5.5 2.1 2.3 1.8 5.5 3.5 4.5 2.1 3.0 7.8 11.3 1.5 0.8 4.1 2.1 9.1 2.7 3.6 3.1 3.7 8.5 3.2 1.7 6.7 1.2 2.4 3.6 7.7 4.5 0.9 0.8 0.8 0.7 5.9 2.1 0.0 0.8 6.0 2.7 6.7 0.7 2.6 17.7 8.9 0.0 2.8 8.5 0.4 4.8 7.1 8.2 1.0 4.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 21.7 22.1 27.7 26.3 22.3 22.7 23.1 21.7 22.9 18.7 21.0 21.5 2.0 0.0 3.7 8.8 1.6 4.8 0.4 2.3 8.6 2.0 1.5 2.9 4.1 4.3 2.5 1.8 0.0 0.6 0.7 0.6 0.0 0.1 20.4 2.4 2.1 1.8 0.0 6.9 10.2 0.2 0.3 4.8 1.5 0.9 11.4 2.9 2.2 1.8 0.3 1.7 8.1 0.5 2.0 1.0 2.3 4.1 1.5 1.2 0.0 1.9 0.1 0.8 0.0 7.1 6.9 0.0 0.0 0.7 0.8 0.4 0.4 0.2 11.1 2.5 0.0 2.2 2.9 5.8 1.0 6.2 4.5 0.3 1.8 0.1 0.6 0.2 NPR1 "ANPa, ANPRA, GUCY2A, NPRA" ENSG00000169418 "Natriuretic peptide receptor 1" P16066 1 153678688-153693992 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor, Vasoactive" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 67.1" "Group enriched" "Detected in many" 6 "Adipocytes: 99.6;Endothelial cells: 52.5;Hepatic stellate cells: 132.8" "Group enriched" "Detected in all" 4 "ovarian cancer: 39.2;renal cancer: 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "ASC diff: 158.5" "Region enriched" "Detected in all" 5 "olfactory bulb: 18.7" "Low region specificity" "Detected in many" HPA031087 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoli "Nucleoplasm, Plasma membrane" "HPA031087: AB_10601975" "unprognostic (2.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.55e-1)" "unprognostic (6.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.03e-1)" "unprognostic (2.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.06e-1)" "unprognostic (1.74e-2)" 67.1 8.7 1.7 3.4 1.5 0.0 44.3 1.4 1.4 8.8 1.5 10.1 1.5 31.0 5.5 4.3 36.4 5.9 15.8 1.3 1.4 28.8 4.3 24.2 2.3 1.5 1.5 27.7 3.9 8.4 3.8 17.7 1.5 4.4 2.0 0.1 3.7 12.1 7.2 6.6 9.3 9.7 1.8 2.2 8.8 1.3 2.4 1.9 14.0 11.1 1.3 12.8 9.7 1.4 0.0 1.3 0.1 0.0 158.5 0.6 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 28.0 0.0 19.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 15.9 0.0 0.0 2.1 0.0 0.1 0.0 1.9 0.0 5.7 1.0 0.1 0.0 0.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.5 1.4 1.4 1.3 1.4 1.5 1.5 1.5 1.8 2.4 1.4 99.6 0.0 6.9 0.0 0.2 1.5 0.5 0.0 0.6 0.0 0.5 0.5 4.5 2.8 0.0 14.7 0.0 0.2 0.1 0.0 0.0 0.7 9.1 6.2 8.8 52.5 0.0 0.0 0.0 0.0 1.3 15.2 0.0 15.4 0.0 0.0 132.8 2.4 0.3 0.0 0.0 0.0 0.0 4.7 4.0 11.5 10.2 0.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 1.0 0.0 4.1 0.0 0.5 0.0 4.0 0.0 0.0 0.0 1.4 2.2 0.5 0.1 0.2 1.0 0.7 0.3 1.4 0.2 0.0 NPR2 "AMDM, ANPb, ANPRB, GUCY2B, NPRB" ENSG00000159899 "Natriuretic peptide receptor 2" P20594 9 35791591-35809732 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Osteogenesis" "Lyase, Receptor" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 35.6;Excitatory neurons: 69.1;Inhibitory neurons: 68.9;Microglial cells: 34.7;Oligodendrocyte precursor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 30.9;ASC TERT1: 21.1;BJ hTERT+: 20.2;HHSteC: 20.1;HSkMC: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.93e-2)" "unprognostic (8.22e-3)" "unprognostic (9.25e-3)" "unprognostic (3.59e-2)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.40e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-1)" "unprognostic (3.99e-2)" "unprognostic (6.99e-3)" "unprognostic (7.10e-2)" "unprognostic (3.24e-1)" "unprognostic (7.86e-2)" 12.4 8.2 9.3 1.7 9.4 0.3 10.3 14.4 9.9 25.7 7.7 15.6 1.8 20.5 8.7 3.2 15.1 3.2 12.8 9.1 11.4 6.7 8.6 9.1 2.3 11.8 9.4 9.4 3.2 1.3 13.8 4.7 11.5 10.9 2.8 4.1 5.3 6.5 10.8 8.3 7.5 9.9 8.2 4.9 7.8 4.8 10.7 2.2 6.0 8.6 1.7 12.1 14.7 7.9 0.0 2.9 2.2 0.0 30.9 21.1 1.9 9.3 20.2 7.0 6.4 4.5 4.3 1.8 3.0 17.9 12.8 1.2 3.6 0.2 6.1 2.2 1.0 1.8 4.3 3.4 20.1 0.4 0.0 23.8 1.8 8.9 0.6 7.6 12.7 2.5 0.7 0.2 13.4 1.0 0.5 0.8 3.5 1.0 3.7 2.4 0.2 0.5 1.8 1.4 1.1 0.7 0.4 0.1 0.6 3.8 0.2 0.0 8.2 8.5 7.8 3.2 1.2 0.5 0.6 4.8 10.4 0.6 5.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 9.3 9.4 14.4 9.9 9.1 11.4 11.8 9.4 11.5 8.2 10.7 7.9 2.7 3.2 3.4 35.6 0.0 1.1 0.6 0.6 1.2 5.1 0.7 1.4 0.7 1.5 0.3 0.0 2.1 0.4 0.5 0.7 0.0 0.6 0.3 1.4 9.2 4.4 0.0 0.0 69.1 0.8 0.2 7.2 0.5 2.0 1.3 9.6 6.1 4.5 0.4 3.3 68.9 0.7 0.0 0.3 2.1 0.3 9.3 0.3 0.0 34.7 0.0 6.8 0.0 51.8 16.3 0.6 3.6 7.9 0.2 2.7 0.2 0.6 1.1 2.2 0.0 5.1 3.4 4.5 3.1 0.1 1.6 0.3 0.7 0.8 1.1 0.4 NR1H3 "LXR-a, LXRa, RLD-1" ENSG00000025434 "Nuclear receptor subfamily 1 group H member 3" Q13133 11 47248300-47269033 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 66.6;Hofbauer cells: 54.4;Kupffer cells: 100.9;Proximal enterocytes: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 13.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 45.3;HSkMC: 61.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036443, CAB037109" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB037109: AB_1840991, HPA036443: AB_10966142" "unprognostic (2.95e-3)" "unprognostic (5.31e-3)" "unprognostic (5.19e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.19e-1)" "unprognostic (2.65e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.51e-1)" "unprognostic (1.76e-1)" "unprognostic (7.73e-2)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (3.56e-1)" "unprognostic (4.42e-2)" "unprognostic (2.84e-1)" "prognostic favorable (3.40e-4)" 60.7 19.9 11.3 19.4 11.8 3.3 51.1 11.2 14.3 25.3 10.2 24.6 48.4 13.6 17.6 7.6 20.3 19.6 18.5 10.3 11.1 23.4 83.8 24.1 46.7 11.0 12.1 15.2 16.7 6.8 7.2 25.4 11.7 19.4 12.0 2.2 14.8 11.5 9.1 11.7 41.0 7.9 10.5 53.2 16.3 21.8 13.8 11.0 20.3 6.3 13.6 22.4 17.5 11.5 3.5 13.8 6.4 6.1 41.0 45.3 31.1 3.5 17.9 5.7 8.8 17.0 43.2 6.1 6.5 2.8 2.1 9.2 7.6 6.1 3.8 5.8 6.1 8.3 18.7 26.1 17.5 2.9 1.0 61.2 3.7 8.7 5.5 9.7 5.0 9.4 10.2 2.5 4.5 14.8 5.8 17.0 7.1 18.7 4.5 8.4 8.3 4.1 5.0 31.9 6.1 2.3 12.2 7.9 10.4 6.1 19.5 8.8 1.3 4.5 6.1 9.1 2.0 11.9 18.3 7.6 8.2 3.9 2.2 7.8 2.7 2.5 1.4 13.3 1.9 1.0 1.5 1.3 4.3 0.7 1.7 1.4 1.6 5.8 4.2 0.7 3.8 1.9 11.3 11.8 11.2 14.3 10.3 11.1 11.0 12.1 11.7 10.5 13.8 11.5 27.2 0.0 11.3 8.1 3.0 3.3 8.6 4.6 2.2 2.4 12.7 12.1 6.6 15.7 4.9 5.5 2.1 11.0 1.5 24.4 11.7 5.8 31.0 2.4 15.3 12.5 1.8 7.0 9.2 8.7 13.3 14.1 17.9 2.8 13.3 7.1 24.7 66.6 54.4 1.7 10.9 14.6 2.0 100.9 3.3 49.0 9.0 24.7 3.6 1.0 5.4 4.4 2.1 3.0 5.6 4.2 10.7 6.0 2.4 4.1 69.5 26.1 2.5 0.8 19.7 7.4 16.3 32.4 16.8 3.0 2.4 6.6 2.1 5.4 19.0 6.3 OCEL1 FLJ22709 ENSG00000099330 "Occludin/ELL domain containing 1" Q9H607 19 17226213-17229219 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "liver: 75.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 137.0;Proximal tubular cells: 150.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 34.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042070, HPA043223" Uncertain Approved "Golgi apparatus" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA042070: AB_2677830, HPA043223: " "unprognostic (6.34e-2)" "unprognostic (6.28e-2)" "unprognostic (3.13e-1)" "unprognostic (3.00e-3)" "unprognostic (6.40e-2)" "unprognostic (2.06e-2)" "unprognostic (4.33e-3)" "unprognostic (2.02e-1)" "unprognostic (1.16e-1)" "unprognostic (1.67e-1)" "unprognostic (7.73e-2)" "unprognostic (4.64e-1)" "unprognostic (1.34e-1)" "unprognostic (2.52e-1)" "unprognostic (2.88e-1)" "unprognostic (9.19e-2)" "unprognostic (1.18e-3)" 18.3 21.6 14.9 4.7 15.8 5.6 16.4 15.9 24.9 14.8 15.5 20.9 19.0 13.5 18.9 9.4 18.1 5.8 17.4 14.6 15.6 37.4 75.5 14.6 7.3 17.4 16.0 11.2 22.7 7.2 9.2 6.7 17.0 21.1 12.3 8.9 14.9 9.0 14.0 8.8 20.0 7.2 16.4 17.3 22.1 6.7 16.5 6.7 20.5 13.5 9.5 13.9 12.3 15.8 8.2 6.4 3.3 2.9 34.9 13.8 8.5 5.3 14.5 4.1 7.2 4.6 9.8 7.2 19.5 7.8 3.6 3.9 4.5 5.4 3.8 6.0 5.3 6.7 6.8 22.6 11.7 1.4 10.5 11.1 5.6 4.8 8.1 14.2 5.9 8.9 5.8 6.8 7.5 6.7 3.7 4.0 5.6 12.3 11.3 2.7 2.8 18.2 17.7 11.2 1.1 5.6 3.3 10.8 9.4 6.9 16.4 6.8 3.9 2.6 3.0 5.1 2.6 18.5 15.3 5.8 7.7 6.3 1.2 27.7 30.8 15.2 9.9 20.9 9.5 15.7 15.1 11.4 23.3 17.0 16.5 10.8 9.7 16.0 17.1 10.0 19.1 13.4 14.9 15.8 15.9 24.9 14.6 15.6 17.4 16.0 17.0 16.4 16.5 15.8 14.6 12.8 8.2 3.9 16.4 6.4 26.7 18.8 17.1 11.4 21.4 23.7 7.3 27.1 21.9 20.2 2.1 38.6 23.9 66.8 60.7 21.4 6.3 59.3 12.5 15.6 17.4 9.7 4.7 27.1 46.0 17.2 25.5 20.4 15.9 8.0 25.0 93.5 25.8 25.2 5.2 40.5 10.2 26.1 7.5 14.6 28.3 22.3 16.0 3.7 19.2 29.6 24.7 1.0 4.6 21.0 67.4 23.3 23.2 20.7 137.0 150.5 71.8 9.7 32.9 12.5 25.8 7.8 13.8 8.8 6.7 103.2 16.4 19.9 28.1 21.9 OLFML2A FLJ00237 ENSG00000185585 "Olfactomedin like 2A" Q68BL7 9 124777133-124814885 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 40.1;Endothelial cells: 21.2;Fibroblasts: 29.0;Skeletal myocytes: 63.0;Smooth muscle cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 160.0;GAMG: 34.0;HeLa: 39.8;hTERT-RPE1: 38.0;WM-115: 64.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021180, HPA022254" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 240000 "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA021180: AB_1854790, HPA022254: AB_1854791" "unprognostic (1.12e-1)" "unprognostic (3.07e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-1)" "unprognostic (4.01e-2)" "unprognostic (1.27e-1)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (1.26e-3)" "unprognostic (7.53e-2)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (3.73e-5)" "unprognostic (5.72e-3)" "unprognostic (3.30e-2)" "unprognostic (7.91e-2)" "unprognostic (1.05e-2)" 15.4 2.9 2.6 2.7 3.1 0.3 11.1 2.2 4.6 25.0 3.3 29.9 3.3 25.3 2.8 8.2 6.4 4.8 16.4 2.2 2.4 4.3 0.7 10.5 2.4 2.8 2.1 12.0 4.8 4.6 2.8 7.0 2.8 7.4 6.2 2.2 7.0 12.2 10.8 16.0 6.9 16.0 2.1 32.8 5.5 1.1 2.6 3.1 19.1 10.0 3.7 17.6 14.6 2.1 0.8 14.6 1.2 0.4 16.8 160.0 0.1 1.8 8.2 3.5 3.5 0.2 2.2 0.0 3.4 0.1 34.0 25.5 0.4 0.8 4.0 0.0 0.1 0.0 39.8 0.1 0.9 0.0 0.1 11.3 2.7 10.2 1.4 38.0 0.0 0.0 0.0 0.2 1.8 0.4 0.0 0.3 3.4 0.0 0.9 0.0 9.5 0.0 0.0 1.2 0.0 0.1 2.9 0.2 4.3 28.6 3.9 0.5 0.1 5.2 4.6 5.5 0.7 1.9 0.0 0.1 15.2 0.8 64.1 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.1 2.6 3.1 2.2 4.6 2.2 2.4 2.8 2.1 2.8 2.1 2.6 2.1 40.1 0.0 1.3 0.7 0.4 12.0 5.9 17.5 6.2 0.6 2.9 8.3 13.8 1.5 5.5 0.0 2.1 0.3 0.5 0.0 0.0 0.1 0.7 0.2 1.5 21.2 0.0 0.0 0.4 0.6 0.3 29.0 0.5 0.2 0.0 0.9 3.6 0.1 0.1 0.0 0.6 0.0 4.1 1.5 7.9 1.4 2.8 0.9 10.6 8.4 0.1 0.3 0.0 0.0 0.1 0.0 0.0 1.5 0.1 4.0 0.0 0.1 11.5 4.0 13.1 63.0 36.4 0.4 0.7 4.5 8.4 0.0 0.6 4.2 0.0 3.5 OLFML2B DKFZP586L151 ENSG00000162745 "Olfactomedin like 2B" Q68BL8 1 161983192-162023869 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 48.3" "Cell type enhanced" "Detected in many" "Early spermatids: 122.5;Hofbauer cells: 38.4;Skeletal myocytes: 175.5;Smooth muscle cells: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 6.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 11 "monocytes: 6.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.7;HSkMC: 113.3;RH-30: 88.5" "Group enriched" "Detected in all" 4 "hippocampal formation: 41.0;white matter: 11.9" "Low region specificity" "Detected in all" "HPA054136, HPA062739" Approved Approved Cytosol "Secreted - unknown location" NA NA 12000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA054136: AB_2682397, HPA062739: AB_2684858" "unprognostic (2.97e-2)" "unprognostic (1.79e-1)" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (6.01e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (5.97e-3)" "unprognostic (7.32e-2)" "unprognostic (7.68e-3)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.01e-12)" "unprognostic (1.64e-3)" "unprognostic (2.11e-2)" "unprognostic (4.53e-3)" "unprognostic (1.97e-2)" 23.4 6.9 4.2 19.2 7.5 0.4 14.7 2.4 5.6 16.8 6.0 18.3 2.1 16.2 5.0 3.9 11.4 48.3 6.6 5.7 3.4 3.1 0.8 15.3 14.0 3.7 4.0 4.2 1.4 3.5 2.8 40.6 4.7 5.3 2.9 0.2 10.4 6.9 10.2 10.1 5.5 22.0 3.0 10.2 3.3 15.9 9.8 3.7 20.8 6.5 11.2 16.8 7.3 4.2 0.1 0.4 6.6 2.2 21.0 39.7 0.0 2.3 10.6 4.3 11.8 0.0 0.2 0.0 0.3 25.7 4.3 0.0 0.6 0.1 2.5 0.0 0.8 0.5 0.2 0.0 0.3 0.1 0.8 113.3 0.0 5.3 0.0 2.1 0.7 0.0 0.0 1.0 19.3 0.1 0.1 0.2 2.1 0.0 1.0 0.2 88.5 8.9 1.6 0.1 0.8 0.3 9.1 0.0 0.6 19.6 0.0 0.1 0.1 2.7 0.7 4.0 3.6 0.0 0.1 0.0 25.1 2.7 1.3 0.0 0.4 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 5.5 0.0 0.0 0.2 4.2 7.5 2.4 5.6 5.7 3.4 3.7 4.0 4.7 3.0 9.8 4.2 4.1 0.0 0.6 0.0 0.2 3.3 0.1 0.1 0.0 0.1 0.4 1.0 3.0 1.5 0.7 1.8 0.0 0.3 0.1 0.0 0.0 0.0 122.5 1.2 24.9 1.7 0.0 0.4 2.8 0.0 0.3 21.9 0.0 0.7 1.3 1.1 1.1 0.2 38.4 0.0 0.9 0.1 0.0 31.1 9.0 12.9 20.8 16.6 1.8 8.4 0.9 0.8 0.0 0.0 2.9 0.0 0.0 29.3 0.1 0.1 0.0 0.1 0.1 0.1 6.6 175.5 57.2 8.8 1.7 0.1 2.3 0.3 0.6 16.4 0.0 0.0 OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 136.6;Fibroblasts: 246.9;Leydig cells: 73.3;Theca cells: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 577.3;ASC TERT1: 312.6;BJ hTERT+: 374.8;HSkMC: 581.6;LHCN-M2: 602.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" 85.6 42.6 5.7 24.9 7.4 0.9 89.7 7.2 12.4 170.6 8.2 71.9 15.1 124.7 42.6 26.6 96.3 95.0 56.6 5.4 6.7 34.1 36.3 55.4 12.0 9.8 7.7 177.4 35.2 9.9 17.9 111.8 8.6 42.9 34.5 0.2 16.7 73.8 10.3 37.6 32.3 94.6 9.2 9.9 48.4 9.3 9.7 8.9 21.8 38.2 14.9 71.1 98.8 11.2 0.0 19.7 9.7 0.1 577.3 312.6 0.6 77.1 374.8 26.5 85.3 25.2 0.2 0.0 4.1 222.4 0.2 0.0 3.2 0.3 4.0 0.0 0.0 0.0 0.1 19.3 149.6 0.2 0.0 581.6 0.0 37.2 0.5 10.7 2.1 0.0 0.0 0.1 602.3 0.3 0.2 0.4 45.8 0.0 0.7 0.1 142.6 0.3 0.0 0.0 0.3 5.4 0.1 0.2 10.5 143.3 224.6 0.9 1.8 14.9 27.6 5.9 0.0 0.2 0.1 0.0 7.3 0.0 94.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 7.4 7.2 12.4 5.4 6.7 9.8 7.7 8.6 9.2 9.7 11.2 13.6 0.0 3.7 0.0 0.4 13.0 0.2 0.0 0.6 0.0 2.1 2.9 1.4 4.3 0.8 1.8 0.0 6.8 1.1 0.2 0.0 0.8 2.9 6.2 136.6 9.5 6.0 0.0 0.0 0.0 4.9 246.9 5.6 3.5 1.3 0.3 45.7 0.5 33.3 0.0 0.0 0.6 0.0 5.9 22.7 1.7 73.3 15.5 12.4 16.9 0.6 0.0 0.0 0.0 0.1 0.3 0.1 33.1 0.2 0.7 0.0 0.5 0.0 0.1 0.0 44.8 28.0 0.3 0.4 1.2 11.5 12.4 2.6 126.1 0.2 0.2 OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 66.8;Hepatic stellate cells: 26.4;Leydig cells: 97.9;Peritubular cells: 110.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ASC diff: 6.1;ASC TERT1: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" 13.9 6.9 2.4 0.3 3.2 0.2 12.6 3.0 6.0 15.5 4.1 4.8 0.8 7.6 7.5 4.3 9.4 8.1 20.0 2.4 2.3 1.9 1.1 4.6 0.9 2.3 2.4 12.0 1.7 0.8 3.9 2.8 2.5 5.0 1.9 0.1 2.2 3.4 1.3 3.3 3.2 8.4 2.3 0.4 4.4 3.1 2.4 0.9 8.9 11.3 2.8 5.5 3.9 2.2 0.0 0.0 0.0 0.0 6.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.4 0.4 0.4 0.0 0.3 0.6 0.5 0.2 0.2 0.1 0.3 0.5 0.4 2.4 3.2 3.0 6.0 2.4 2.3 2.3 2.4 2.5 2.3 2.4 2.2 4.4 0.0 0.0 0.0 0.3 2.7 0.4 0.1 0.0 0.9 0.1 0.1 1.3 4.3 0.6 1.8 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.3 11.4 7.8 0.0 0.0 1.7 0.0 0.2 66.8 2.0 0.3 0.0 0.1 26.4 0.0 0.3 0.0 1.5 0.0 0.0 0.3 3.3 3.2 97.9 0.2 1.8 9.4 0.0 0.0 0.0 1.0 1.6 0.0 0.0 110.2 0.8 0.2 0.0 0.1 0.0 1.6 0.0 2.2 2.9 0.2 0.1 0.3 2.7 0.0 0.4 0.1 0.0 0.2 OPN3 "ECPN, encephalopsin, ERO, NMO-1, PPP1R116" ENSG00000054277 "Opsin 3" Q9H1Y3 1 241590102-241677376 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 18.7" "Cell type enhanced" "Detected in many" "Early spermatids: 133.9;Extravillous trophoblasts: 252.9;Langerhans cells: 206.8;Syncytiotrophoblasts: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 10.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 72.4" "Low region specificity" "Detected in all" "CAB013682, HPA064443" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "CAB013682: , HPA064443: AB_2685267" "unprognostic (2.41e-2)" "prognostic unfavorable (3.17e-5)" "unprognostic (1.75e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (7.12e-2)" "unprognostic (5.10e-3)" "unprognostic (1.24e-2)" "unprognostic (2.39e-1)" "unprognostic (4.96e-1)" "unprognostic (2.66e-2)" "unprognostic (3.44e-1)" "unprognostic (9.13e-2)" "unprognostic (9.15e-3)" "unprognostic (2.61e-2)" "unprognostic (7.12e-2)" "unprognostic (9.44e-3)" 2.6 2.2 5.0 3.4 5.5 1.1 3.1 4.1 9.6 2.7 3.2 6.4 1.6 3.8 4.4 4.2 4.5 3.1 2.1 5.8 4.3 4.2 11.0 8.4 4.4 3.5 6.4 2.1 1.9 1.4 2.7 18.7 3.4 1.0 5.5 0.5 2.3 1.3 1.8 2.2 2.9 1.8 3.5 4.5 3.3 2.5 7.1 4.9 3.2 4.0 5.1 4.2 2.9 5.3 4.5 15.0 10.7 0.8 38.3 72.4 8.2 8.0 6.0 5.6 5.6 1.1 12.5 0.6 0.4 9.7 6.3 25.9 3.4 5.7 5.6 16.7 0.8 0.0 3.2 9.5 19.4 3.9 8.3 37.0 15.5 3.5 8.4 37.7 11.5 13.4 7.6 2.3 9.1 2.4 1.4 5.0 29.1 19.3 8.0 6.3 0.6 14.6 38.5 6.7 2.8 10.9 5.0 15.6 4.6 21.5 0.8 14.9 13.9 1.3 1.0 2.2 8.6 5.3 8.7 0.7 4.3 12.4 16.7 0.0 0.8 0.7 0.0 1.1 0.0 1.8 0.1 0.1 2.2 1.7 0.2 0.3 0.3 0.5 1.1 10.0 0.2 0.5 5.0 5.5 4.1 9.6 5.8 4.3 3.5 6.4 3.4 3.5 7.1 5.3 3.7 6.4 5.4 4.9 35.5 14.7 13.5 12.7 18.8 3.3 12.4 10.5 0.8 15.7 7.0 12.9 0.0 80.6 60.1 41.4 13.7 16.8 133.9 10.5 5.8 5.9 4.2 15.1 56.7 10.5 252.9 7.7 12.8 22.2 2.5 22.4 8.6 26.3 26.6 0.0 15.7 8.8 20.3 31.9 206.8 89.7 11.1 56.9 28.4 9.4 30.2 4.3 5.2 10.1 7.2 19.3 10.8 16.6 18.4 20.1 7.6 21.5 2.7 2.1 0.0 5.4 13.3 7.8 8.3 29.7 12.4 171.6 6.4 6.6 7.1 15.2 OR51E2 PSGR ENSG00000167332 "Olfactory receptor family 51 subfamily E member 2" Q9H255 11 4680171-4697854 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 9.6;prostate: 28.9" "Cell type enriched" "Detected in some" 6 "Enteroendocrine cells: 77.4" "Cancer enriched" "Detected in some" 274 "prostate cancer: 217.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.9;BJ hTERT+: 1.1;hTERT-RPE1: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "unprognostic (1.98e-3)" "unprognostic (1.91e-1)" "unprognostic (6.09e-3)" "unprognostic (1.57e-2)" "unprognostic (8.00e-4)" "unprognostic (3.61e-2)" "unprognostic (6.27e-2)" "unprognostic (1.66e-1)" "unprognostic (3.05e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-1)" "unprognostic (3.61e-1)" "unprognostic (5.04e-5)" "unprognostic (3.34e-2)" "unprognostic (4.66e-2)" "unprognostic (5.76e-2)" "unprognostic (3.29e-1)" 0.6 0.2 0.3 1.0 0.4 0.1 0.5 0.4 0.5 0.7 0.6 9.6 0.2 1.3 0.3 0.0 0.5 0.3 0.2 0.4 0.2 0.4 0.0 0.0 0.0 0.3 0.3 0.6 0.1 0.0 0.0 4.0 0.4 28.9 2.2 0.1 0.0 2.3 0.4 0.2 0.8 2.1 0.1 0.0 0.4 0.3 0.5 0.0 0.1 0.4 0.0 0.4 0.2 0.7 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.4 0.5 0.4 0.2 0.3 0.3 0.4 0.1 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 77.4 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 ORAI3 "MGC13024, TMEM142C" ENSG00000175938 "ORAI calcium release-activated calcium modulator 3" Q9BRQ5 16 30949068-30956461 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 77.3;Hofbauer cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 94.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015022 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" "HPA015022: AB_1854807" "unprognostic (1.17e-1)" "unprognostic (3.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.15e-2)" "unprognostic (8.29e-2)" "unprognostic (1.46e-1)" "unprognostic (8.60e-2)" "unprognostic (8.54e-2)" "unprognostic (3.15e-1)" "unprognostic (1.33e-3)" "unprognostic (1.77e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (3.87e-5)" "unprognostic (2.30e-2)" "unprognostic (4.46e-2)" "unprognostic (6.43e-3)" "unprognostic (9.17e-3)" 17.3 34.1 18.0 8.2 16.5 17.6 15.2 16.9 17.1 24.4 26.0 22.7 9.2 18.3 16.3 15.4 19.2 9.9 16.7 15.3 16.3 19.3 70.2 14.2 11.9 18.6 18.5 18.9 17.7 18.9 18.0 14.9 17.1 26.3 8.6 4.0 14.6 17.0 7.9 14.3 16.1 9.8 17.4 22.5 17.1 15.6 20.5 11.2 16.4 8.1 10.6 27.2 20.2 17.7 2.8 15.8 8.1 10.7 68.1 60.7 0.6 9.3 62.3 6.8 17.2 1.5 26.1 3.9 20.7 17.9 27.5 12.7 1.4 17.6 4.6 12.3 5.2 10.2 4.9 16.1 94.9 11.2 30.5 65.5 45.9 13.1 25.5 63.8 11.7 2.2 11.7 20.6 22.1 10.8 0.7 42.6 6.6 9.1 4.3 8.6 6.3 30.8 26.2 6.8 2.0 13.5 8.4 2.6 14.9 19.5 19.7 45.5 8.5 5.1 3.5 11.4 2.2 50.4 4.0 3.1 25.3 26.4 7.9 23.2 8.7 26.6 3.4 9.2 3.6 7.1 1.8 2.7 8.5 6.7 2.2 2.9 15.3 11.7 12.6 9.5 2.7 3.3 18.0 16.5 16.9 17.1 15.3 16.3 18.6 18.5 17.1 17.4 20.5 17.7 12.1 6.4 10.8 0.0 23.9 7.9 24.5 25.6 32.5 1.5 11.1 19.6 6.9 5.7 11.6 16.5 2.1 28.1 25.9 11.1 13.7 21.4 61.1 16.5 21.8 16.5 15.0 16.2 0.0 11.4 2.7 25.9 4.1 10.5 7.0 17.9 23.6 77.3 93.8 35.3 0.0 11.3 10.2 43.7 11.5 36.7 53.1 31.4 21.4 0.0 39.1 24.4 17.5 0.0 0.0 9.5 18.4 43.2 18.1 14.0 9.5 48.2 14.7 3.6 26.3 11.0 14.0 26.5 2.5 17.0 4.5 4.4 9.7 61.0 5.8 20.4 OSBPL1A "ORP-1, ORP1, OSBPL1B" ENSG00000141447 "Oxysterol binding protein like 1A" Q9BXW6 18 24162045-24397880 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 214.3;Oligodendrocytes: 433.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 22 "basophil: 93.4" "Lineage enriched" "Detected in many" 22 "granulocytes: 93.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040959, HPA043401" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040959: AB_10964295, HPA043401: AB_10960208" "unprognostic (1.75e-2)" "unprognostic (3.35e-2)" "unprognostic (9.84e-3)" "unprognostic (4.92e-3)" "unprognostic (2.34e-1)" "unprognostic (3.06e-2)" "unprognostic (5.82e-2)" "unprognostic (2.06e-1)" "unprognostic (5.88e-2)" "unprognostic (2.62e-2)" "unprognostic (2.41e-1)" "unprognostic (8.53e-2)" "prognostic favorable (4.98e-13)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.18e-2)" "unprognostic (5.42e-3)" "unprognostic (1.56e-1)" 72.0 27.8 77.1 9.4 105.6 15.4 47.9 99.6 136.0 52.4 114.0 34.9 20.7 48.0 17.2 30.8 29.6 21.1 52.0 77.3 90.6 43.5 13.3 24.2 10.4 89.7 95.0 27.3 16.5 62.8 18.7 8.3 94.5 23.0 22.7 82.2 51.5 26.2 170.9 17.5 20.2 41.1 79.2 9.9 21.3 14.3 91.3 9.6 29.0 123.1 7.9 25.4 20.0 136.8 38.2 11.4 26.3 49.1 60.0 48.7 24.5 14.0 40.4 12.4 10.2 7.1 38.9 0.1 16.0 25.1 19.7 37.9 10.4 24.4 11.4 0.2 19.6 12.1 7.8 0.2 29.9 30.4 6.0 63.4 34.4 9.5 38.4 54.0 15.9 10.4 0.0 0.3 15.5 16.1 7.0 9.1 21.7 19.5 36.8 0.0 21.0 3.2 3.3 27.7 16.9 16.6 32.6 37.5 46.1 24.5 13.7 21.7 3.4 45.9 9.4 14.9 13.6 0.4 5.3 1.0 22.3 8.7 26.8 93.4 4.2 1.1 0.2 2.2 0.1 0.0 0.8 0.6 4.1 0.4 0.6 0.5 1.6 0.2 0.7 4.1 0.8 1.5 77.1 105.6 99.6 136.0 77.3 90.6 89.7 95.0 94.5 79.2 91.3 136.8 214.3 16.0 21.6 142.0 5.4 20.1 43.4 16.6 29.6 66.6 73.6 64.3 78.0 41.5 20.0 20.2 22.9 12.1 11.1 23.6 64.6 13.3 67.7 27.6 55.3 89.9 4.8 18.7 180.3 7.4 8.1 59.9 16.3 17.0 17.2 137.9 37.5 12.4 26.6 25.2 166.4 40.0 40.7 27.4 17.9 76.4 42.9 34.3 58.7 67.5 11.0 124.8 0.0 75.9 433.0 10.7 19.1 54.9 2.5 27.1 29.8 71.7 21.7 112.3 32.9 44.7 65.8 6.7 9.9 27.2 10.2 6.4 3.8 103.7 16.2 26.4 OSR2 FLJ90037 ENSG00000164920 "Odd-skipped related transciption factor 2" Q8N2R0 8 98944403-98952104 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 166.1;endometrium 1: 155.1;fallopian tube: 155.3" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 243.1;Leydig cells: 784.1;Peritubular cells: 758.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 16 "ASC diff: 542.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052425, HPA063486" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA052425: AB_2681826, HPA063486: AB_2685022" "unprognostic (1.72e-1)" "unprognostic (1.92e-3)" "unprognostic (1.03e-1)" "unprognostic (5.94e-2)" "unprognostic (1.57e-1)" "prognostic favorable (2.44e-5)" "unprognostic (1.70e-2)" "unprognostic (1.15e-2)" "unprognostic (1.89e-2)" "unprognostic (3.73e-3)" "unprognostic (3.01e-2)" "unprognostic (6.19e-2)" "unprognostic (1.57e-7)" "unprognostic (1.37e-2)" "unprognostic (2.39e-1)" "unprognostic (2.56e-4)" "unprognostic (8.54e-3)" 45.0 9.9 0.0 2.4 0.0 0.6 26.0 0.2 0.2 166.1 0.0 9.2 0.6 155.1 53.7 15.1 155.3 12.9 4.2 0.0 0.0 1.3 0.3 3.6 2.4 0.0 0.0 93.2 4.2 3.0 2.7 8.2 0.0 40.2 3.8 0.0 6.8 72.2 5.6 27.9 24.9 47.1 0.0 0.2 5.1 35.6 0.0 0.8 5.6 5.1 1.1 27.2 83.8 0.0 32.3 4.5 0.0 4.4 542.4 17.2 4.3 17.6 33.1 13.7 13.6 3.4 3.9 0.0 2.9 26.7 0.8 12.4 2.7 4.7 6.7 1.5 13.0 0.6 3.3 1.6 8.9 0.9 0.6 17.0 9.8 2.3 1.6 0.8 0.0 4.8 4.0 0.4 0.6 14.6 2.9 5.7 0.0 2.6 2.8 13.8 1.6 1.1 1.1 2.7 1.4 0.1 1.9 7.5 0.4 0.3 4.3 7.5 0.2 2.1 0.1 13.9 1.0 0.7 0.5 0.3 0.9 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.9 14.1 6.6 3.4 1.2 0.0 7.9 5.3 0.7 0.0 3.3 0.0 0.0 17.2 0.9 0.7 0.0 0.0 5.8 7.8 243.1 3.7 0.0 0.0 0.0 0.0 138.4 71.7 0.5 5.9 0.0 0.2 0.0 0.0 9.3 0.0 0.0 18.4 10.2 1.9 21.9 24.1 784.1 2.7 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.8 758.3 4.6 3.6 103.9 0.1 1.7 0.0 32.9 8.8 21.3 5.1 4.5 0.3 9.1 24.2 2.3 95.6 22.3 2.2 OST4 ENSG00000228474 "Oligosaccharyltransferase complex subunit 4, non-catalytic" P0C6T2 2 27070472-27071654 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 32: Non-specific - Translation" "unprognostic (5.15e-2)" "unprognostic (4.42e-2)" "unprognostic (2.24e-1)" "unprognostic (3.63e-1)" "unprognostic (5.95e-2)" "unprognostic (1.95e-3)" "prognostic unfavorable (5.11e-4)" "unprognostic (2.66e-1)" "unprognostic (1.18e-1)" "unprognostic (2.88e-2)" "unprognostic (7.89e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (7.35e-5)" "unprognostic (1.33e-1)" "unprognostic (8.52e-2)" "unprognostic (1.38e-1)" "unprognostic (9.88e-2)" 302.0 323.9 359.4 276.6 368.6 446.0 288.7 370.1 440.9 365.2 371.6 366.6 255.3 214.6 458.9 268.4 258.6 297.8 541.4 357.5 387.2 313.6 392.9 220.8 370.4 373.4 375.4 329.2 295.3 377.2 169.0 232.2 375.8 268.4 327.6 146.3 411.8 320.7 396.9 211.7 298.1 325.7 375.9 260.8 269.2 137.9 371.6 443.2 277.0 534.2 352.1 480.9 231.8 387.8 526.7 444.8 492.1 336.3 1362.9 1154.9 327.7 635.8 749.7 386.9 559.9 450.5 435.2 248.4 427.1 1044.1 572.4 244.1 321.3 701.9 305.9 486.4 491.5 527.4 300.4 1082.4 769.3 386.5 465.7 1235.3 591.0 509.8 468.3 952.9 916.5 490.1 337.2 509.8 882.5 641.8 472.7 710.4 293.7 1029.8 695.8 274.1 543.6 617.9 906.6 577.2 289.7 660.5 337.8 541.2 469.8 622.6 294.5 449.5 683.7 541.5 461.0 409.5 449.6 835.8 720.7 893.5 551.9 427.2 466.0 3182.5 1405.3 2129.1 1337.7 1230.8 1558.0 1748.5 1752.0 1469.2 1341.1 1473.3 1607.2 1551.1 1133.7 1049.8 1221.4 2614.4 1818.9 4735.8 359.4 368.6 370.1 440.9 357.5 387.2 373.4 375.4 375.8 375.9 371.6 387.8 370.4 176.3 301.9 13.7 522.3 411.2 417.7 1106.0 233.9 58.1 754.0 1020.4 369.3 377.4 595.2 663.9 20.9 527.6 555.4 597.3 1195.4 611.5 211.3 296.4 453.3 395.7 435.1 465.9 4.7 661.7 841.8 394.3 215.6 561.8 460.2 316.1 616.8 808.5 843.3 33.7 6.1 993.1 573.7 569.5 600.1 142.5 504.2 577.1 597.7 6.5 1041.6 309.1 632.4 9.5 13.5 668.3 725.3 429.1 749.7 509.8 1012.6 1348.1 310.0 81.8 295.9 230.7 492.5 242.3 392.6 424.9 589.0 577.1 532.4 299.2 669.3 620.6 PAMR1 "DKFZP586H2123, RAMP" ENSG00000149090 "Peptidase domain containing associated with muscle regeneration 1" Q6UXH9 11 35431823-35530300 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Astrocytes: 380.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 86.9;ASC TERT1: 354.7;BJ hTERT+: 357.7;fHDF/TERT166: 86.7;HSkMC: 123.1;U-87 MG: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA 5600000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (3.38e-1)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.07e-2)" "unprognostic (6.92e-2)" "unprognostic (3.32e-2)" "unprognostic (4.07e-2)" "unprognostic (1.91e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.08e-5)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.08e-1)" "unprognostic (9.98e-2)" "unprognostic (8.25e-2)" 32.8 14.9 25.1 0.6 27.4 0.0 15.4 22.0 23.2 59.9 13.9 14.9 4.5 58.2 18.3 10.0 22.6 20.3 23.2 22.5 26.2 7.1 12.6 5.9 1.3 37.9 35.9 3.4 5.3 1.7 6.4 55.9 32.4 21.2 6.6 0.9 5.7 17.9 2.7 19.8 9.9 14.9 46.1 5.7 5.4 0.2 34.1 2.8 7.0 9.0 1.7 28.0 41.3 38.8 0.0 0.0 0.1 0.0 86.9 354.7 0.1 42.8 357.7 4.9 8.3 32.7 0.0 0.0 0.0 86.7 0.1 0.1 0.0 0.0 3.3 0.0 0.8 0.0 0.0 0.0 50.1 0.0 0.0 123.1 1.8 9.7 1.3 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.7 0.0 0.2 0.0 0.2 0.2 0.0 8.4 0.1 0.0 0.0 0.0 0.0 14.3 2.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 82.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 27.4 22.0 23.2 22.5 26.2 37.9 35.9 32.4 46.1 34.1 38.8 2.5 0.0 0.0 380.3 0.0 19.1 1.4 14.8 1.2 0.1 0.7 19.7 1.3 0.0 2.4 1.8 0.0 2.2 0.0 0.0 0.0 1.4 0.1 4.5 26.2 1.1 0.0 0.0 13.1 0.0 1.4 50.2 1.1 0.8 0.0 0.6 0.0 0.0 2.0 0.0 8.2 0.2 0.0 0.0 5.5 0.1 0.3 0.5 1.8 28.1 0.6 0.0 0.0 9.5 1.4 0.1 0.0 0.0 0.0 0.4 0.2 0.0 1.8 0.2 0.0 1.6 5.8 0.0 0.2 0.1 9.2 3.4 0.6 0.2 0.0 0.2 PAPPA "ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1" ENSG00000182752 "Pappalysin 1" Q13219 9 116153791-116402321 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "placenta: 72.3" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 92.2;Collecting duct cells: 165.5;Endometrial stromal cells: 101.3;Proximal tubular cells: 51.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 50.0;ASC TERT1: 37.8;HSkMC: 137.4;U-138 MG: 36.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA001667, CAB016724" Enhanced "Secreted in female reproductive system" NA NA 78000000 "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "CAB016724: , HPA001667: AB_1854960" "unprognostic (3.25e-1)" "unprognostic (6.18e-6)" "unprognostic (2.47e-1)" "unprognostic (6.49e-2)" "unprognostic (2.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (5.42e-3)" "unprognostic (5.44e-2)" "unprognostic (3.87e-2)" "unprognostic (6.87e-3)" "unprognostic (8.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.37e-3)" "unprognostic (2.48e-1)" "unprognostic (4.01e-1)" "unprognostic (1.02e-3)" 4.1 1.5 0.7 1.8 0.2 0.0 0.8 0.5 0.9 4.2 2.2 2.0 0.3 3.9 0.6 2.5 3.1 2.0 2.6 0.3 1.6 3.8 0.3 1.9 1.2 2.5 2.5 2.5 0.8 9.1 0.4 72.3 2.0 1.1 1.5 1.0 0.4 2.1 0.3 0.9 0.9 4.2 0.4 0.3 1.1 0.8 1.6 0.8 1.0 1.4 1.0 4.5 2.4 1.3 0.0 14.9 22.3 0.0 50.0 37.8 0.0 12.2 21.4 3.3 5.6 0.0 0.0 0.0 0.0 8.6 1.1 1.7 0.0 0.0 15.6 0.0 0.0 2.6 12.8 0.1 24.3 0.0 0.0 137.4 0.0 16.4 1.9 26.9 0.1 0.0 0.5 0.0 3.8 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.6 0.0 0.6 0.1 0.1 1.2 1.8 0.0 0.0 6.8 0.0 0.0 28.9 36.3 1.8 1.0 1.4 0.0 0.0 0.0 25.8 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.5 0.9 0.3 1.6 2.5 2.5 2.0 0.4 1.6 1.3 0.2 0.0 1.5 3.9 1.0 2.9 0.2 4.0 92.2 17.6 0.8 0.4 3.4 0.0 1.6 165.5 12.5 0.5 0.1 0.1 9.8 5.9 20.1 4.7 101.3 1.4 0.0 0.0 10.0 0.9 19.5 31.8 0.5 2.6 1.3 10.4 4.6 0.1 0.4 0.0 19.6 0.0 0.0 0.0 5.8 17.9 14.3 1.0 1.8 7.5 0.0 2.5 1.0 15.1 2.9 0.3 0.0 8.6 1.2 1.2 0.2 51.5 1.6 2.9 0.0 3.3 10.9 2.2 0.6 19.7 1.1 14.0 1.3 0.2 0.1 0.3 PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.2" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 72.3;Fibroblasts: 56.3;Leydig cells: 37.9;Peritubular cells: 58.6;Sertoli cells: 19.7;Smooth muscle cells: 25.5;Theca cells: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 148.2;ASC diff: 175.0;ASC TERT1: 190.8;BJ hTERT+: 86.8;fHDF/TERT166: 143.3;HHSteC: 129.4;HSkMC: 195.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 5900000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Golgi apparatus" "HPA017976: AB_1855045" "unprognostic (2.77e-1)" "unprognostic (1.86e-2)" "unprognostic (3.73e-3)" "unprognostic (9.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.39e-2)" "unprognostic (2.36e-1)" "unprognostic (4.30e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-2)" "unprognostic (8.76e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-2)" "unprognostic (6.27e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.71e-4)" 22.2 5.2 2.6 7.9 3.0 0.1 13.5 2.8 3.2 25.3 2.6 12.2 9.3 30.4 11.2 6.4 11.7 22.5 6.5 2.5 4.8 7.1 2.1 7.2 1.7 4.1 5.8 21.0 1.5 2.0 2.4 44.2 3.8 17.5 13.8 2.1 6.5 13.5 2.6 4.1 8.7 18.4 3.2 6.4 6.7 4.5 3.9 3.6 5.1 23.2 1.4 10.8 8.4 3.0 0.0 0.3 148.2 0.0 175.0 190.8 0.1 27.4 86.8 5.0 7.7 0.3 0.0 0.0 0.1 143.3 0.4 0.4 34.2 0.7 2.6 0.2 1.0 0.0 0.0 0.0 129.4 0.0 0.1 195.9 0.3 9.4 3.8 4.7 1.0 0.7 0.0 0.6 2.8 0.0 3.9 0.1 0.3 0.0 2.7 11.7 4.1 0.0 0.0 0.1 0.0 9.6 0.0 0.0 0.2 38.3 0.9 0.0 0.0 69.3 4.2 13.9 0.5 0.2 0.0 0.0 3.9 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.0 2.8 3.2 2.5 4.8 4.1 5.8 3.8 3.2 3.9 3.0 3.4 0.0 0.5 1.3 0.0 4.1 0.4 0.1 2.2 2.5 1.1 1.7 1.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.6 1.9 72.3 3.0 0.0 0.0 0.2 0.0 0.3 56.3 0.0 1.7 0.0 6.4 2.5 0.0 3.1 0.0 9.0 0.0 0.0 0.0 7.8 1.3 37.9 0.9 1.8 10.3 0.0 6.8 0.0 0.0 0.6 0.0 0.0 58.6 0.1 0.0 0.0 0.1 0.0 0.2 19.7 6.6 25.5 0.6 0.1 1.2 2.6 0.8 0.7 18.5 0.0 0.1 PCDHGA2 PCDH-GAMMA-A2 ENSG00000081853 "Protocadherin gamma subfamily A, 2" Q9Y5H1 5 141338760-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Bipolar cells: 3.2;Cardiomyocytes: 1.8;Fibroblasts: 1.5;Leydig cells: 1.2;Peritubular cells: 2.6;Skeletal myocytes: 1.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.4;BJ: 3.9;fHDF/TERT166: 4.4;HSkMC: 3.4;hTERT-RPE1: 3.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA038625" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Nucleoli, Focal adhesion sites, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA038625: AB_2732480" "unprognostic (2.43e-3)" "unprognostic (2.10e-2)" "unprognostic (1.32e-2)" "unprognostic (4.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.14e-1)" "unprognostic (3.01e-1)" "unprognostic (2.82e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (4.32e-2)" "unprognostic (8.45e-3)" "unprognostic (9.68e-3)" "unprognostic (1.04e-2)" "unprognostic (1.18e-2)" "unprognostic (2.23e-4)" 2.2 1.6 1.8 0.7 1.4 0.0 1.9 2.7 2.5 3.0 0.7 1.5 0.1 2.9 1.9 0.8 3.1 1.4 4.9 2.9 1.5 1.1 0.7 2.0 0.2 3.8 3.2 6.3 1.8 3.8 2.6 0.7 2.6 1.9 0.3 2.3 1.2 2.2 1.0 1.0 0.6 2.1 3.5 0.6 0.9 2.3 2.6 0.8 1.6 1.1 0.2 1.4 1.7 2.2 0.0 0.7 0.3 0.2 2.8 6.4 0.0 3.9 1.3 0.3 0.5 0.0 0.0 0.1 0.4 4.4 0.5 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.4 0.1 0.0 0.2 3.9 1.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.1 0.5 0.0 0.2 0.5 0.0 2.3 0.1 0.3 0.4 0.0 2.3 0.6 0.3 0.2 0.0 0.0 0.3 0.0 1.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.4 2.7 2.5 2.9 1.5 3.8 3.2 2.6 3.5 2.6 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 3.2 0.3 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 1.1 0.9 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.1 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.4 0.0 0.4 0.0 1.5 0.5 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGA4 PCDH-GAMMA-A4 ENSG00000262576 "Protocadherin gamma subfamily A, 4" Q9Y5G9 5 141355021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.0;Skeletal myocytes: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 7.4;BJ: 4.3;HSkMC: 4.3;HUVEC TERT2: 4.3;U-87 MG: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.27e-2)" "unprognostic (4.55e-3)" "unprognostic (2.00e-2)" "unprognostic (6.54e-4)" "unprognostic (1.87e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-1)" "unprognostic (1.20e-2)" "unprognostic (5.62e-2)" "unprognostic (3.76e-1)" "unprognostic (6.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.94e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-2)" "unprognostic (1.65e-1)" "unprognostic (2.31e-4)" 1.7 1.3 1.6 0.4 1.8 0.0 0.9 3.7 1.7 1.3 0.0 0.9 0.2 1.6 0.8 0.4 0.9 0.8 1.5 2.9 1.5 0.4 0.3 1.0 0.1 2.1 2.4 1.6 2.1 2.3 1.0 0.8 1.7 1.1 0.3 1.5 0.8 1.1 0.7 0.5 0.3 1.5 2.0 0.3 0.4 0.7 2.1 0.2 0.7 1.0 0.1 0.7 0.8 2.5 0.0 0.1 0.8 0.4 3.3 7.4 0.0 4.3 3.4 0.2 0.8 0.0 0.1 0.7 1.4 3.7 1.3 0.0 0.1 0.1 0.4 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.3 4.3 0.1 0.0 0.0 2.6 4.3 0.0 0.1 0.2 1.8 0.6 0.2 0.2 0.1 0.0 0.2 0.3 1.2 0.1 0.2 0.0 0.6 1.3 0.2 0.2 0.9 0.3 1.6 0.0 2.8 1.8 0.5 2.4 0.3 0.1 0.2 0.1 6.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.8 3.7 1.7 2.9 1.5 2.1 2.4 1.7 2.0 2.1 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 PCDHGA5 "CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5" ENSG00000253485 "Protocadherin gamma subfamily A, 5" Q9Y5G8 5 141364232-141512979 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.5;Endometrial stromal cells: 9.2;Horizontal cells: 10.1;Sertoli cells: 6.6;Skeletal myocytes: 5.7" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 15.8;ASC TERT1: 6.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.61e-2)" "unprognostic (1.04e-2)" "unprognostic (5.28e-2)" "unprognostic (4.83e-1)" "unprognostic (6.60e-3)" "unprognostic (5.71e-2)" "unprognostic (8.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.07e-1)" "unprognostic (9.40e-2)" "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" "unprognostic (5.90e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (8.38e-4)" 1.0 0.6 1.0 0.3 1.6 0.1 1.2 4.9 1.1 2.5 0.0 1.1 0.1 2.0 0.6 0.8 1.4 1.1 1.9 1.2 1.2 0.3 0.2 1.1 0.2 2.2 2.1 2.0 0.6 0.6 0.9 0.6 1.0 1.4 0.3 1.2 0.8 0.9 0.6 0.7 0.4 1.0 1.2 0.2 0.5 0.3 1.2 0.3 0.5 0.7 0.1 1.0 1.3 2.0 0.0 0.4 0.2 0.1 15.8 6.2 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.8 0.3 0.3 0.8 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.0 1.5 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.5 0.6 0.3 0.5 0.6 0.1 0.0 0.3 0.8 0.6 0.1 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.2 1.4 0.0 0.9 0.5 0.1 0.9 0.6 0.1 0.9 0.1 0.3 0.1 0.7 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 1.0 1.6 4.9 1.1 1.2 1.2 2.2 2.1 1.0 1.2 1.2 2.0 1.8 0.0 1.1 0.0 0.2 0.1 0.8 0.1 0.6 11.5 0.3 0.4 2.6 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.4 9.2 1.9 0.0 0.0 0.0 0.2 0.0 4.0 0.0 0.2 1.3 0.6 1.4 0.3 0.1 10.1 0.0 0.0 0.0 0.3 0.0 0.0 3.7 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.5 0.0 0.1 0.1 1.3 6.6 5.7 1.7 0.0 0.3 0.3 0.0 0.0 0.6 0.9 0.0 0.4 PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 "Protocadherin gamma subfamily B, 1" Q9Y5G3 5 141350102-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5" "Cell type enhanced" "Detected in some" "Early spermatids: 5.7;Late spermatids: 7.6;Melanocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.9;ASC TERT1: 6.6;hTERT-RPE1: 7.1;T-47d: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076182" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites,Midbody" Yes No "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "Vesicles, Plasma membrane" "Nucleoplasm, Focal adhesion sites, Midbody" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076182: AB_2686783" "unprognostic (1.53e-2)" "unprognostic (1.94e-3)" "unprognostic (3.21e-1)" "unprognostic (4.38e-3)" "unprognostic (2.98e-1)" "unprognostic (8.36e-3)" "unprognostic (2.37e-1)" "unprognostic (9.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.06e-1)" "unprognostic (3.44e-2)" "unprognostic (4.78e-2)" "unprognostic (6.33e-2)" "unprognostic (3.15e-2)" "unprognostic (8.75e-2)" "unprognostic (1.93e-1)" "unprognostic (7.63e-3)" 0.6 0.7 1.8 0.1 1.2 0.0 0.5 2.1 1.6 0.6 0.0 0.3 0.0 1.2 0.4 0.3 0.4 0.5 0.5 2.9 1.6 0.4 0.1 0.6 0.0 1.9 3.3 1.4 0.8 2.3 1.0 0.2 2.4 0.6 0.1 1.6 0.3 0.9 0.2 0.2 0.1 0.9 2.4 0.1 0.1 0.4 1.8 0.0 0.6 0.3 0.0 0.3 0.3 3.5 0.1 1.9 1.6 0.0 12.9 6.6 0.1 1.2 3.2 0.5 0.7 0.2 0.5 0.5 4.2 0.5 3.1 0.6 0.3 0.2 0.4 0.0 0.8 0.0 0.2 1.2 0.2 0.0 0.0 1.0 0.0 0.0 0.0 7.1 0.1 0.0 0.2 0.2 3.0 1.7 0.4 0.3 0.2 0.0 0.0 0.0 2.4 0.1 0.0 0.0 1.0 0.7 0.0 0.8 0.1 1.2 8.6 0.0 1.0 0.2 1.3 1.1 0.0 0.0 2.4 0.3 2.5 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.2 2.1 1.6 2.9 1.6 1.9 3.3 2.4 2.4 1.8 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 "Protocadherin gamma subfamily B, 2" Q9Y5G2 5 141360042-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.2;Cardiomyocytes: 1.4;Endometrial stromal cells: 1.0;Fibroblasts: 1.2" "Cancer enriched" "Detected in many" 5 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.5;ASC TERT1: 9.8;LHCN-M2: 8.2;REH: 7.8" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077526" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane, Cytosol" Nucleoplasm "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077526: AB_2732350" "unprognostic (7.14e-3)" "unprognostic (8.79e-3)" "unprognostic (3.21e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-4)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.78e-1)" "unprognostic (1.05e-1)" "unprognostic (8.46e-3)" "unprognostic (4.59e-2)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (1.29e-1)" "unprognostic (3.36e-4)" 1.5 1.0 2.6 0.6 3.6 0.1 1.1 6.3 2.8 2.1 0.0 1.1 0.2 3.0 0.9 0.9 1.6 1.9 1.8 3.1 3.2 0.7 0.7 1.7 0.3 3.7 3.3 2.8 0.8 1.2 0.9 1.1 3.6 1.3 0.8 1.6 0.8 1.2 0.8 0.8 0.5 1.5 3.0 0.6 0.6 0.5 2.2 0.4 0.7 0.9 0.3 0.9 1.1 5.5 0.1 0.3 2.0 0.2 13.5 9.8 0.1 2.1 2.9 0.6 3.2 0.0 0.3 3.7 1.0 1.7 7.1 0.5 0.4 0.3 1.0 0.0 0.2 0.0 0.3 0.4 0.5 0.2 0.2 2.5 0.5 0.2 0.1 4.7 1.7 0.1 0.2 1.2 8.2 0.5 2.9 0.7 0.1 0.9 0.9 7.8 2.6 0.2 0.2 0.3 1.5 1.6 0.2 0.4 0.4 1.5 3.0 0.2 5.9 2.9 0.6 4.4 3.9 0.2 2.2 0.6 3.1 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.6 6.3 2.8 3.1 3.2 3.7 3.3 3.6 3.0 2.2 5.5 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.6 2.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGB3 PCDH-GAMMA-B3 ENSG00000262209 "Protocadherin gamma subfamily B, 3" Q9Y5G1 5 141370242-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.4;ASC TERT1: 8.4;fHDF/TERT166: 3.5;TIME: 5.5" "HPA008755, HPA010580, HPA035822, HPA035823" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA035822: , HPA035823: AB_2674802" "unprognostic (6.93e-3)" "unprognostic (9.10e-4)" "unprognostic (1.35e-1)" "unprognostic (7.05e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (7.83e-2)" "unprognostic (1.92e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (3.51e-2)" "unprognostic (5.81e-2)" "unprognostic (3.11e-1)" "unprognostic (3.62e-2)" "unprognostic (3.89e-2)" "unprognostic (2.80e-3)" 0.7 0.3 0.4 0.2 0.8 0.0 0.5 3.8 0.8 0.8 0.0 0.8 0.0 1.0 0.6 0.3 0.7 0.4 1.2 0.9 0.5 0.3 0.2 0.5 0.2 1.3 1.4 1.2 0.7 1.1 0.7 0.4 0.6 0.4 0.3 0.8 0.8 0.4 0.5 0.6 0.3 0.7 0.6 0.4 0.4 0.4 0.8 0.3 0.6 0.5 0.2 0.6 0.6 1.4 0.0 0.6 0.4 0.3 10.4 8.4 0.2 1.2 2.0 0.7 0.8 0.0 0.0 1.8 0.3 3.5 0.6 0.5 0.0 0.2 0.5 0.0 0.2 0.0 0.2 0.1 0.4 0.1 0.0 2.1 0.4 0.2 0.1 0.2 1.0 0.0 0.2 0.8 0.2 0.4 0.6 0.9 0.1 0.0 0.1 1.5 0.6 0.0 0.2 0.1 2.4 0.5 0.0 0.0 0.2 0.3 0.6 0.0 5.5 0.5 0.1 0.5 0.6 0.2 1.8 0.2 0.4 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 3.8 0.8 0.9 0.5 1.3 1.4 0.6 0.6 0.8 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGB5 PCDH-GAMMA-B5 ENSG00000276547 "Protocadherin gamma subfamily B, 5" Q9Y5G0 5 141397987-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Bipolar cells: 1.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 66.3;ASC TERT1: 49.6;BJ hTERT+ SV40 Large T+: 29.2;BJ hTERT+ SV40 Large T+ RasG12V: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (2.71e-3)" "unprognostic (1.95e-2)" "unprognostic (1.09e-1)" "unprognostic (4.14e-2)" "unprognostic (2.35e-1)" "unprognostic (1.20e-1)" "unprognostic (3.64e-2)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.29e-1)" "unprognostic (1.69e-4)" "unprognostic (9.63e-3)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.25e-4)" 2.8 2.7 3.6 1.1 3.6 0.0 1.8 5.8 3.1 2.0 3.3 1.7 0.7 3.1 2.0 1.9 2.8 1.6 2.9 3.9 6.4 2.2 2.1 2.7 0.4 5.1 4.7 5.7 3.8 20.3 1.7 4.8 5.4 3.0 0.9 3.1 4.7 3.9 2.1 3.8 0.8 2.8 5.3 1.3 1.5 1.9 4.9 1.3 4.5 1.9 0.8 1.9 2.1 6.1 0.0 2.4 0.3 0.0 66.3 49.6 1.3 18.3 0.0 29.2 32.5 2.9 10.0 10.6 23.4 20.5 0.0 13.9 0.0 7.6 16.4 0.0 3.1 0.0 0.0 0.1 6.9 0.0 6.5 17.6 1.5 1.7 9.4 12.6 9.0 0.0 0.2 0.0 1.0 8.1 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.0 0.1 0.0 0.1 0.0 2.0 19.1 0.1 9.2 0.0 2.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 3.6 5.8 3.1 3.9 6.4 5.1 4.7 5.4 5.3 4.9 6.1 0.5 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.2 1.5 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.6 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.8 0.5 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.1 PCK1 PEPCK-C ENSG00000124253 "Phosphoenolpyruvate carboxykinase 1" P35558 20 57561080-57568121 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Kinase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 432.1;liver: 681.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 703.8;Distal tubular cells: 588.9;Hepatocytes: 1184.0;Proximal enterocytes: 2209.9;Proximal tubular cells: 3547.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 99.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "ASC diff: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006277, HPA006507, CAB017027" Approved NA NA 840000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB017027: , HPA006277: AB_1079579, HPA006507: AB_1079578" "unprognostic (3.50e-2)" "unprognostic (5.60e-2)" "unprognostic (4.60e-2)" "unprognostic (8.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.84e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.47e-5)" "unprognostic (1.03e-1)" "unprognostic (6.40e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-1)" 59.2 1.1 0.8 1.7 0.8 0.0 29.8 0.7 1.6 0.0 0.6 57.8 110.4 1.2 0.2 0.4 0.9 5.0 1.0 0.7 1.4 432.1 681.4 0.2 0.3 0.7 0.9 1.6 0.4 0.0 21.1 0.3 0.8 0.2 79.8 0.5 1.1 0.2 0.4 0.9 143.9 2.9 0.6 0.3 0.9 0.0 1.3 0.1 0.8 6.5 0.0 0.8 0.1 0.8 0.0 0.0 0.0 0.0 20.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.6 0.7 1.4 0.7 0.9 0.8 0.6 1.3 0.8 0.7 0.0 0.0 0.0 21.3 0.1 0.0 0.0 15.9 0.3 0.7 0.6 1.0 61.5 0.6 90.1 0.0 0.1 0.1 703.8 588.9 0.6 0.1 1.3 1.5 2.7 53.9 40.2 0.0 0.0 0.0 2.3 19.9 8.5 8.9 0.1 29.6 1184.0 0.0 3.3 0.0 293.6 0.0 22.6 0.0 0.0 0.0 12.8 0.0 1.9 0.0 9.9 0.0 0.0 0.0 0.1 285.5 0.0 0.0 0.0 2209.9 3547.9 0.0 0.4 0.0 0.3 6.0 0.0 0.1 10.3 0.3 0.3 10.2 1.5 348.5 0.1 PCYOX1 "KIAA0908, PCL1" ENSG00000116005 "Prenylcysteine oxidase 1" Q9UHG3 2 70257386-70281185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 599.4;Hepatocytes: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 313.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035193 Approved "Intracellular and membrane" NA NA 510000000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA035193: AB_10602017" "unprognostic (1.09e-1)" "unprognostic (1.72e-2)" "unprognostic (7.91e-2)" "unprognostic (1.15e-2)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (6.87e-2)" "unprognostic (6.28e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (1.61e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.26e-2)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" 78.5 33.5 15.4 12.7 15.7 3.7 34.4 12.1 18.4 56.5 29.3 26.9 24.9 39.9 33.6 38.8 35.6 31.7 37.7 14.7 27.8 92.6 103.5 56.2 14.6 16.5 22.0 39.6 20.6 66.0 17.9 29.0 24.9 44.3 23.6 30.7 70.1 46.6 92.1 33.0 24.5 40.8 14.6 15.6 22.1 14.2 28.4 11.1 60.0 50.4 14.2 25.7 25.2 13.2 38.8 54.9 43.2 48.6 313.2 160.0 37.9 64.8 59.4 35.4 26.5 86.5 33.6 4.0 27.3 89.2 58.2 62.2 31.7 50.2 40.5 22.1 26.9 14.9 41.0 75.7 31.4 14.1 12.7 154.9 54.1 47.4 13.3 93.9 42.6 14.2 27.0 27.8 50.7 23.6 10.7 22.8 26.1 55.9 23.1 19.6 90.2 34.5 50.1 42.8 11.3 24.1 97.8 47.7 45.5 61.0 39.1 18.2 53.4 59.2 32.7 52.9 34.2 22.9 55.1 5.1 71.3 19.3 22.1 16.3 6.5 6.8 8.3 5.4 10.4 3.7 8.0 6.7 5.9 2.8 10.8 9.2 4.1 6.1 6.0 7.4 7.8 6.5 15.4 15.7 12.1 18.4 14.7 27.8 16.5 22.0 24.9 14.6 28.4 13.2 37.3 599.4 77.5 16.0 12.2 21.3 23.1 43.9 29.6 48.7 46.0 31.8 81.1 40.0 49.9 53.3 43.8 43.4 12.1 30.7 7.9 26.7 1.7 18.4 65.9 33.4 8.5 12.0 24.7 10.2 36.0 81.9 22.4 36.2 10.1 20.9 39.7 187.8 22.1 57.2 36.8 21.0 36.7 17.4 9.2 3.9 89.2 14.3 24.9 23.4 8.6 90.3 11.3 21.6 18.0 13.9 21.0 120.7 26.2 27.0 47.7 69.0 25.0 36.9 72.3 65.5 63.7 14.7 32.2 40.8 28.3 22.0 14.5 56.2 26.5 18.4 PDE1A ENSG00000115252 "Phosphodiesterase 1A" P54750 2 182140036-182523192 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 46.6;thyroid gland: 45.8" "Cell type enhanced" "Detected in many" "Early spermatids: 396.3;Excitatory neurons: 764.9;Late spermatids: 592.1;Oligodendrocytes: 1178.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC diff: 37.2;HHSteC: 22.0;HSkMC: 47.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022151 Approved Approved Nucleoplasm NA NA "Cluster 43: Testis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA022151: AB_1855118" "unprognostic (3.63e-1)" "unprognostic (7.21e-2)" "unprognostic (1.32e-1)" "unprognostic (8.61e-2)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (3.84e-1)" "unprognostic (3.82e-1)" "unprognostic (1.02e-1)" "unprognostic (5.38e-2)" "unprognostic (2.78e-1)" "unprognostic (2.86e-1)" "unprognostic (5.55e-3)" "unprognostic (2.50e-3)" "unprognostic (5.96e-2)" "unprognostic (1.37e-1)" "unprognostic (1.40e-3)" 10.5 4.4 16.9 4.6 20.4 0.0 5.0 35.5 23.4 17.2 2.4 11.8 3.0 8.7 8.0 5.6 10.3 23.7 15.6 30.3 8.4 46.6 3.9 3.6 2.1 2.6 4.2 10.9 2.1 2.2 2.7 1.2 5.4 3.6 6.7 1.4 2.0 5.4 2.8 2.2 5.7 12.9 3.7 3.1 5.6 35.6 16.5 8.4 45.8 5.0 0.9 9.7 9.8 18.2 0.0 0.2 3.9 0.0 37.2 3.1 0.1 0.3 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 4.7 0.0 5.1 0.0 22.0 0.0 0.0 47.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.5 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.7 0.0 5.4 0.1 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.9 20.4 35.5 23.4 30.3 8.4 2.6 4.2 5.4 3.7 16.5 18.2 6.7 0.0 2.6 15.3 0.0 1.3 2.0 0.1 8.0 20.0 0.3 0.3 5.9 1.5 1.4 27.6 0.0 0.1 0.0 0.1 185.9 0.5 396.3 0.3 0.4 8.9 0.0 0.0 764.9 0.4 0.0 18.6 0.0 0.8 0.0 0.1 5.0 0.0 0.1 0.0 185.8 1.0 0.0 0.0 1.8 592.1 14.9 0.4 0.0 30.0 0.0 0.3 0.0 18.1 1178.0 0.2 0.1 8.2 0.2 2.6 0.1 1.5 0.0 1.2 52.6 21.0 45.1 9.1 4.9 1.0 1.3 0.0 0.2 7.6 0.1 0.7 PDE4DIP "CMYA2, KIAA0454, KIAA0477, MMGL" ENSG00000178104 "Phosphodiesterase 4D interacting protein" Q5VU43 1 148808181-149048286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 729.5;skeletal muscle: 2164.0;tongue: 1379.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 702.6;Rod photoreceptor cells: 272.3;Syncytiotrophoblasts: 309.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 289.6;ASC TERT1: 233.8;K-562: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012678 Supported "Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" "HPA012678: AB_1855123" "unprognostic (2.14e-1)" "unprognostic (3.27e-1)" "unprognostic (5.31e-2)" "unprognostic (6.73e-2)" "unprognostic (7.82e-2)" "unprognostic (1.16e-2)" "unprognostic (2.17e-1)" "unprognostic (9.72e-2)" "unprognostic (7.65e-2)" "unprognostic (1.67e-1)" "unprognostic (2.23e-2)" "unprognostic (5.08e-2)" "unprognostic (1.70e-3)" "unprognostic (1.82e-1)" "unprognostic (4.14e-2)" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" 32.9 16.9 103.0 20.9 82.9 15.8 22.3 142.7 106.1 28.0 32.4 22.5 24.2 17.4 73.5 37.9 19.8 19.5 729.5 115.5 118.5 42.0 63.5 36.1 21.7 102.2 95.6 8.6 21.4 84.6 53.1 68.5 109.7 29.2 25.4 173.3 34.9 22.9 2164.0 26.1 29.4 18.8 96.8 17.2 29.7 9.2 139.9 12.1 16.9 1379.7 23.2 24.0 17.1 114.9 39.2 7.5 10.6 11.6 289.6 233.8 60.7 45.2 42.3 42.7 55.7 35.5 24.1 19.8 13.7 64.5 121.3 19.8 25.7 31.5 72.1 14.7 36.8 10.0 16.2 14.2 76.2 8.8 10.2 167.5 61.9 181.7 97.8 96.9 17.1 16.3 222.1 45.0 76.8 66.2 6.9 5.4 37.1 32.3 15.9 14.6 26.5 7.7 25.4 39.9 50.1 4.7 44.1 123.4 36.1 44.7 37.5 11.7 22.9 49.3 11.2 124.7 100.9 19.9 29.6 29.1 200.6 8.0 30.2 10.6 5.7 4.5 5.3 6.1 5.5 12.0 10.6 7.1 7.0 11.0 8.1 4.5 1.3 4.9 2.1 3.0 14.4 4.8 103.0 82.9 142.7 106.1 115.5 118.5 102.2 95.6 109.7 96.8 139.9 114.9 5.7 51.3 45.1 81.3 24.0 28.8 9.9 19.8 23.3 71.0 16.1 11.3 702.6 24.3 45.4 69.9 114.7 184.6 9.5 24.0 62.6 13.1 38.9 41.1 14.2 15.7 43.2 7.4 85.8 7.1 148.3 54.2 20.4 27.0 13.9 6.1 5.3 80.8 45.0 33.7 81.1 32.0 20.3 46.1 90.4 50.0 10.5 68.7 55.2 6.5 21.5 45.7 14.4 65.9 41.5 4.5 25.1 9.8 37.5 4.1 48.8 20.7 88.0 272.3 32.9 131.2 40.1 8.7 15.9 14.6 16.3 309.2 24.0 4.2 24.2 4.3 PDE7B ENSG00000171408 "Phosphodiesterase 7B" Q9NP56 6 135851701-136195574 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.1" "Cell type enhanced" "Detected in many" "Astrocytes: 346.4;Excitatory neurons: 136.7;Inhibitory neurons: 166.0;Oligodendrocyte precursor cells: 343.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 8.7;ASC TERT1: 10.2;EFO-21: 16.2;HeLa: 9.6;HSkMC: 22.4;HUVEC TERT2: 10.8;U-2197: 11.4" "Region enriched" "Detected in all" 5 "basal ganglia: 125.3" "Low region specificity" "Detected in all" HPA023967 Uncertain Approved Nucleoplasm No NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA023967: AB_1855128" "unprognostic (3.18e-1)" "unprognostic (3.47e-1)" "unprognostic (2.34e-1)" "unprognostic (1.79e-3)" "unprognostic (3.34e-1)" "unprognostic (3.22e-4)" "unprognostic (1.37e-2)" "unprognostic (3.00e-1)" "unprognostic (2.80e-1)" "unprognostic (6.73e-3)" "unprognostic (1.11e-2)" "unprognostic (7.85e-2)" "prognostic favorable (1.59e-4)" "unprognostic (3.14e-3)" "unprognostic (2.68e-2)" "unprognostic (1.43e-1)" "unprognostic (3.34e-2)" 5.2 2.3 6.5 2.2 22.1 0.1 2.6 3.6 8.1 3.9 2.8 2.5 1.9 7.8 2.2 1.3 2.8 3.4 6.6 2.6 8.7 5.5 3.7 1.7 1.5 6.2 11.6 13.0 0.8 6.2 4.8 1.0 6.0 4.3 2.7 2.4 2.9 10.3 4.7 0.8 2.2 7.6 4.6 1.1 3.6 1.5 15.8 3.8 4.7 8.9 0.8 6.0 3.6 2.8 0.0 5.7 0.2 0.0 8.7 10.2 0.1 0.5 2.9 2.1 1.1 0.0 0.1 0.1 16.2 3.6 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 9.6 0.0 3.7 0.1 0.0 22.4 0.0 4.2 0.0 0.9 10.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 3.8 0.7 3.9 3.7 0.1 0.2 0.0 0.0 1.8 0.0 2.3 0.0 11.4 0.0 0.1 0.0 0.0 0.6 0.0 0.9 0.0 0.3 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.8 1.3 0.5 0.3 0.0 0.2 0.0 0.0 0.0 0.1 6.5 22.1 3.6 8.1 2.6 8.7 6.2 11.6 6.0 4.6 15.8 2.8 8.3 0.0 0.5 346.4 11.9 0.4 0.3 0.5 0.0 4.4 0.9 0.4 8.4 2.8 0.2 22.0 0.0 0.1 0.7 0.1 0.0 0.2 0.5 3.1 1.4 23.1 7.3 0.8 136.7 1.6 0.0 9.8 4.6 2.1 10.2 31.1 35.3 3.8 0.3 6.7 166.0 0.0 0.0 1.9 4.8 0.9 12.2 3.2 0.0 70.3 0.7 11.5 0.0 343.8 10.4 0.1 0.0 7.9 0.2 0.4 0.0 1.6 1.6 0.9 13.1 30.6 9.1 0.3 0.1 0.2 1.4 0.0 2.9 4.4 0.0 0.3 PDGFD "IEGF, MSTP036, SCDGF-B" ENSG00000170962 "Platelet derived growth factor D" Q9GZP0 11 103907189-104164379 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 106.5;ovary: 78.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;dendritic cells: 30.0;Ductal cells: 30.6;Fibroblasts: 44.3;Inhibitory neurons: 95.0;Microglial cells: 28.1;NK-cells: 46.4" "Cancer enhanced" "Detected in all" "renal cancer: 17.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "eosinophil: 9.5;gdT-cell: 16.4;memory CD8 T-cell: 7.2;naive CD8 T-cell: 6.0;NK-cell: 17.1" "Group enriched" "Detected in many" 29 "granulocytes: 9.5;NK-cells: 17.1;T-cells: 16.4" "Group enriched" "Detected in many" 6 "ASC diff: 139.8;HHSteC: 42.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 39.4" "HPA046183, HPA066271" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 95000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA046183: AB_2679573, HPA066271: AB_2685645" "unprognostic (2.21e-1)" "unprognostic (9.35e-2)" "unprognostic (5.60e-2)" "unprognostic (1.72e-1)" "unprognostic (5.81e-2)" "unprognostic (8.83e-2)" "unprognostic (2.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (2.26e-1)" "unprognostic (7.01e-3)" "prognostic unfavorable (9.60e-4)" "unprognostic (1.19e-1)" "unprognostic (6.72e-2)" "unprognostic (3.57e-3)" 20.4 106.5 0.5 3.4 0.8 0.9 21.7 0.7 1.3 25.1 9.0 8.8 4.1 11.8 7.1 1.9 9.3 34.0 23.2 0.8 2.2 7.7 2.3 3.1 7.4 5.1 6.6 78.0 25.7 17.1 13.4 7.0 9.4 10.0 9.8 1.5 8.6 37.4 2.2 7.9 4.8 9.7 1.8 2.8 23.4 3.3 2.0 3.7 18.3 8.8 5.4 15.8 15.4 2.3 0.0 7.8 4.0 0.0 139.8 4.2 0.1 0.9 0.8 0.7 0.8 0.0 1.3 7.4 1.4 7.3 5.2 0.4 0.0 0.2 0.3 0.0 3.2 0.2 1.6 0.3 42.6 0.0 0.1 14.7 0.0 0.1 0.0 0.2 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 1.4 0.0 2.1 0.0 6.7 0.0 0.1 9.6 0.0 13.8 3.2 1.8 0.0 2.0 1.0 0.1 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.8 0.6 0.0 9.5 16.4 0.0 1.4 0.4 1.7 7.2 0.0 0.0 0.2 6.0 0.2 17.1 0.1 0.0 0.1 4.2 0.5 0.8 0.7 1.3 0.8 2.2 5.1 6.6 9.4 1.8 2.0 2.3 15.6 0.0 0.0 1.0 1.6 3.1 7.7 0.2 1.8 2.3 1.7 9.4 4.5 32.9 0.6 5.5 0.0 0.2 30.0 0.2 0.0 30.6 8.2 0.8 1.8 10.3 1.8 1.3 13.9 4.4 0.2 44.3 0.0 1.4 0.0 8.1 2.9 0.0 0.3 26.9 95.0 1.0 0.0 1.3 3.7 13.3 0.3 0.8 0.0 28.1 0.9 1.5 46.4 2.0 2.8 3.0 0.5 2.2 8.4 1.6 0.0 0.3 0.0 0.5 6.6 1.9 3.7 0.4 4.3 0.3 2.0 0.0 10.2 5.2 0.6 3.2 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 46.0 28.9 13.9 40.4 13.7 1.6 40.1 8.1 12.8 50.8 18.1 37.7 22.4 44.3 21.8 22.5 50.9 38.5 32.1 11.9 11.0 26.5 16.0 37.9 8.5 16.7 11.9 190.2 13.4 3.0 3.7 62.7 15.1 15.0 35.2 5.3 16.6 18.9 9.6 14.8 31.3 48.1 12.1 46.2 29.4 13.6 8.9 7.6 16.5 41.9 7.2 63.9 38.0 20.0 0.1 0.0 1.0 0.8 468.1 216.1 0.5 25.4 279.4 0.1 0.7 67.6 0.5 0.5 0.5 195.9 0.8 0.6 19.6 0.2 0.1 2.6 1.0 0.7 0.7 1.2 156.3 0.3 0.4 392.0 0.0 31.4 0.0 5.4 0.0 0.7 0.6 0.9 1.1 0.1 0.4 1.2 3.5 0.3 1.1 0.5 0.1 0.1 0.0 0.4 0.6 37.9 0.0 0.5 0.2 2.0 0.7 0.1 0.8 84.9 3.2 93.9 0.2 0.4 0.1 0.8 2.6 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 13.7 8.1 12.8 11.9 11.0 16.7 11.9 15.1 12.1 8.9 20.0 11.1 0.0 0.5 0.3 0.6 17.1 0.6 2.4 1.2 5.5 4.3 3.2 4.8 0.0 0.8 0.0 0.0 1.4 0.9 0.1 1.9 4.2 2.2 11.7 423.9 5.7 0.0 0.0 1.1 6.7 2.0 256.4 5.1 9.0 0.0 2.6 26.0 1.0 3.1 0.0 19.5 0.2 10.2 0.6 27.3 17.2 449.8 5.4 23.2 39.4 4.7 17.5 0.0 499.6 0.4 20.0 0.0 408.9 0.2 0.9 0.0 0.1 0.5 0.6 0.0 25.7 13.9 1.0 3.4 8.1 15.8 1.4 2.5 49.6 0.0 1.0 PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 1288.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC diff: 1350.1;ASC TERT1: 462.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" 171.2 25.1 25.4 27.5 27.2 0.7 106.3 20.5 33.3 155.9 43.5 41.6 11.9 101.1 24.2 24.1 89.6 124.5 75.7 22.1 23.2 49.7 13.4 98.3 27.5 22.1 24.6 105.5 20.8 21.9 23.0 113.3 22.8 56.2 14.1 6.3 34.5 43.3 38.1 65.0 37.9 68.9 19.4 41.4 27.9 18.4 27.7 8.7 66.5 44.1 13.8 58.3 98.6 21.6 0.1 0.3 8.3 0.4 1350.1 462.7 3.0 48.9 202.3 33.5 56.4 5.4 0.0 0.0 6.4 142.0 19.0 0.1 0.1 0.4 15.8 0.0 0.0 0.1 3.3 3.5 190.7 0.0 0.4 210.0 0.0 46.3 0.6 106.6 0.1 0.1 0.1 5.5 5.5 0.0 0.1 0.6 9.0 0.2 0.2 3.7 2.5 0.2 0.0 0.0 0.1 24.8 0.5 0.1 0.0 38.2 0.1 0.6 0.4 53.7 17.2 23.1 2.8 0.4 0.0 0.3 33.4 0.1 1.5 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.0 0.2 25.4 27.2 20.5 33.3 22.1 23.2 22.1 24.6 22.8 19.4 27.7 21.6 50.8 0.0 1.1 81.9 0.5 24.0 0.5 0.0 2.2 6.6 1.4 3.3 17.3 1.5 0.0 1.8 4.2 0.6 6.0 0.3 0.0 0.8 1.6 2.8 99.5 32.2 0.0 0.0 7.9 0.0 1.1 123.5 2.0 2.3 0.0 2.5 6.4 1.9 1.5 0.0 1.3 0.7 0.0 0.0 35.6 10.9 165.3 3.1 24.9 45.0 0.7 50.7 23.7 10.1 3.3 0.1 0.1 203.8 2.3 0.7 0.3 0.1 0.7 2.9 1288.5 6.6 288.3 1.9 1.6 0.8 15.3 0.8 4.8 4.0 0.4 1.1 PDK4 ENSG00000004799 "Pyruvate dehydrogenase kinase 4" Q16654 7 95583499-95596516 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2300.1;tongue: 1216.5" "Cell type enhanced" "Detected in many" "Adipocytes: 681.3;Cardiomyocytes: 764.5;Kupffer cells: 464.0;Proximal enterocytes: 654.2;Smooth muscle cells: 489.7" "Cancer enhanced" "Detected in all" "renal cancer: 107.8;thyroid cancer: 89.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 32.5;eosinophil: 38.1;intermediate monocyte: 63.5;myeloid DC: 16.8;non-classical monocyte: 39.8" "Group enriched" "Detected in many" 12 "dendritic cells: 16.8;granulocytes: 38.1;monocytes: 63.5" "Cell line enriched" "Detected in many" 7 "ASC diff: 482.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056731 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA056731: AB_2683218" "unprognostic (3.18e-3)" "unprognostic (1.98e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (5.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-3)" "unprognostic (3.47e-1)" "unprognostic (6.38e-2)" "unprognostic (2.24e-3)" "unprognostic (1.87e-2)" "unprognostic (8.75e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.80e-4)" "unprognostic (9.15e-2)" "unprognostic (4.20e-2)" "unprognostic (1.12e-1)" 451.2 216.3 32.4 33.4 48.0 2.5 388.7 32.9 43.0 76.3 222.0 278.9 72.3 89.0 10.4 151.5 153.5 80.6 480.4 40.0 35.3 127.8 223.4 120.4 24.0 44.5 41.8 240.8 549.3 18.2 39.9 104.8 45.3 91.2 42.6 2.0 60.2 529.5 2300.1 91.9 163.3 62.2 34.8 99.0 173.1 13.3 39.8 13.8 72.1 1216.5 13.5 187.5 95.2 59.4 0.0 37.7 1.5 9.5 482.2 0.8 0.4 0.0 0.0 0.0 0.0 0.0 12.8 0.0 5.3 1.7 1.6 0.0 0.1 0.0 0.0 0.0 1.3 0.2 66.8 0.0 4.5 0.0 0.0 5.3 0.0 0.0 0.0 0.2 2.4 0.0 1.7 0.0 0.2 0.9 0.0 0.4 0.1 0.0 2.1 0.0 0.0 0.3 23.5 2.6 0.5 2.7 0.0 3.0 8.6 2.4 1.3 1.1 0.0 0.0 0.8 2.1 0.1 0.0 0.0 0.1 1.5 0.0 0.0 0.3 32.5 38.1 0.0 63.5 0.1 0.4 0.0 0.0 16.8 1.5 0.0 0.0 2.5 3.3 39.8 0.5 0.0 14.2 32.4 48.0 32.9 43.0 40.0 35.3 44.5 41.8 45.3 34.8 39.8 59.4 681.3 32.1 16.0 154.4 6.0 10.5 279.2 9.2 19.9 0.1 95.9 40.6 764.5 30.0 36.1 378.9 0.0 5.9 3.9 67.7 13.7 7.2 14.9 151.0 52.1 108.0 55.4 9.3 0.4 5.5 0.7 326.9 158.5 347.5 5.1 19.9 199.2 130.5 49.8 0.0 1.2 96.0 6.1 464.0 21.5 6.7 134.2 204.8 90.7 19.7 19.8 8.4 1.0 7.1 26.2 6.2 46.3 44.8 6.4 110.0 654.2 74.2 66.3 0.4 164.3 293.2 489.7 1.8 1.0 12.3 9.2 10.9 5.3 18.7 60.5 157.4 PDZRN3 "KIAA1095, LNX3, SEMACAP3, SEMCAP3" ENSG00000121440 "PDZ domain containing ring finger 3" Q9UPQ7 3 73382431-73624941 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 256.0;Excitatory neurons: 183.1;Inhibitory neurons: 258.3;Microglial cells: 329.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.9" "Cell line enhanced" "Detected in many" "AF22: 32.1;ASC diff: 57.0;ASC TERT1: 29.6;BJ hTERT+: 42.0;HSkMC: 41.4;U-87 MG: 30.4" "Group enriched" "Detected in many" 4 "amygdala: 15.1;basal ganglia: 8.1;cerebral cortex: 19.5;hippocampal formation: 16.1;white matter: 7.2" "Low region specificity" "Detected in many" "HPA038822, HPA061420" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA038822: AB_10675952, HPA061420: AB_2684512" "unprognostic (3.22e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-2)" "prognostic favorable (3.35e-5)" "unprognostic (1.09e-1)" "unprognostic (5.54e-2)" "unprognostic (8.47e-2)" "unprognostic (3.67e-1)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "prognostic favorable (4.93e-4)" "unprognostic (8.38e-2)" "prognostic favorable (3.65e-7)" "unprognostic (8.63e-3)" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (2.86e-3)" 29.9 35.7 14.9 10.2 16.3 0.0 24.0 8.5 20.9 45.2 58.0 84.0 9.2 64.1 24.5 27.8 26.7 27.4 48.0 16.7 10.6 10.7 2.1 14.9 4.5 13.0 11.8 69.4 6.9 0.8 4.6 17.5 11.0 31.7 13.9 6.3 20.9 29.0 91.8 17.3 24.4 38.4 13.1 2.4 38.7 6.4 17.1 2.9 3.6 22.4 1.4 46.7 32.0 13.2 0.0 0.0 32.1 0.1 57.0 29.6 0.1 16.9 42.0 5.0 3.2 16.2 0.0 0.1 0.1 22.8 0.8 0.0 0.0 0.0 4.8 0.0 2.2 0.0 0.0 0.0 9.5 0.0 0.1 41.4 0.0 13.8 0.1 6.0 0.0 0.0 0.0 0.0 4.9 2.1 0.0 0.2 4.6 0.0 0.2 0.0 8.4 0.1 0.0 0.0 3.7 10.5 0.0 7.8 12.7 9.2 4.5 0.0 0.0 20.6 1.5 23.6 2.2 0.7 0.0 0.2 30.4 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 14.9 16.3 8.5 20.9 16.7 10.6 13.0 11.8 11.0 13.1 17.1 13.2 5.9 0.0 0.0 256.0 0.5 2.4 9.7 0.0 1.8 19.3 7.5 7.6 65.0 0.0 0.0 5.5 6.2 0.5 2.7 1.0 1.9 0.0 0.4 2.1 45.2 2.3 21.1 0.0 183.1 0.4 0.5 25.2 2.0 3.3 0.0 35.0 0.0 0.0 0.8 0.0 258.3 9.1 0.0 0.0 2.9 1.3 23.3 0.7 16.0 329.8 0.0 22.5 0.0 21.6 5.5 0.3 0.9 28.2 0.1 10.9 0.1 7.1 0.0 1.9 0.0 4.6 19.6 0.5 6.2 2.9 1.8 0.8 0.5 12.4 3.9 6.3 PENK ENSG00000181195 Proenkephalin P01210 8 56436674-56446671 "Plasma proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 376.2;brain: 164.1;testis: 129.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 758.4;Leydig cells: 1137.9;Peritubular cells: 225.7;Spermatocytes: 274.1" "Cancer enhanced" "Detected in many" "lung cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 14.3;ASC TERT1: 8.6;BJ: 7.7;THP-1: 7.7" "Region enriched" "Detected in all" 7 "basal ganglia: 3626.9" "Region enriched" "Detected in all" 7 "basal ganglia: 923.2" "HPA013138, CAB016390" Enhanced "Secreted in other tissues" NA NA 220000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB016390: AB_2161515, HPA013138: AB_1855191" "unprognostic (6.89e-2)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" "unprognostic (1.17e-3)" "unprognostic (1.56e-2)" "unprognostic (3.58e-3)" "unprognostic (1.31e-2)" "unprognostic (3.60e-1)" "unprognostic (6.34e-2)" "unprognostic (5.73e-2)" "unprognostic (3.47e-2)" "unprognostic (4.24e-2)" "unprognostic (1.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (3.98e-3)" 8.6 376.2 29.9 4.4 164.1 0.0 4.9 45.2 45.6 9.2 0.5 23.1 1.1 8.1 0.0 1.4 7.6 12.5 25.6 2.7 74.0 0.2 0.2 3.7 0.1 81.4 15.9 29.7 1.1 0.0 17.1 2.9 51.3 22.4 2.0 0.6 2.7 23.4 3.0 0.8 4.2 4.6 54.0 0.1 10.0 129.0 38.0 0.2 1.0 5.3 0.1 0.6 6.2 10.1 0.0 0.0 0.1 0.0 14.3 8.6 0.0 7.7 2.5 1.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 29.9 164.1 45.2 45.6 2.7 74.0 81.4 15.9 51.3 54.0 38.0 10.1 0.2 0.0 1.5 0.3 0.5 0.1 0.2 758.4 0.0 0.3 0.1 0.6 0.8 0.0 8.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 85.7 0.1 3.1 0.9 0.0 0.0 0.4 0.0 0.1 16.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.4 0.0 2.0 0.0 0.7 60.8 1137.9 1.2 0.0 1.9 0.0 0.0 0.0 0.5 0.4 0.0 0.0 225.7 0.0 0.2 0.0 0.0 3.6 0.0 6.6 1.7 1.2 274.1 19.1 0.1 0.4 0.0 0.2 3.1 0.0 0.0 PEX19 "D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1" ENSG00000162735 "Peroxisomal biogenesis factor 19" P40855 1 160276807-160286348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis" "Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044837, HPA051966" Supported Supported Peroxisomes NA NA 7900 "Cluster 34: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Peroxisomes "HPA044837: AB_10962496, HPA051966: AB_2681677" "unprognostic (1.49e-2)" "unprognostic (2.26e-1)" "unprognostic (3.42e-1)" "unprognostic (4.80e-3)" "unprognostic (3.89e-2)" "unprognostic (3.88e-2)" "unprognostic (3.79e-1)" "unprognostic (1.51e-1)" "unprognostic (2.32e-1)" "unprognostic (1.53e-2)" "unprognostic (8.06e-2)" "unprognostic (1.00e-1)" "prognostic favorable (2.92e-5)" "unprognostic (3.46e-2)" "unprognostic (2.25e-1)" "unprognostic (2.19e-2)" "unprognostic (1.24e-2)" 79.3 25.7 21.1 14.5 22.5 12.3 36.5 22.2 23.5 20.3 15.6 22.6 19.4 18.2 25.0 24.9 22.9 19.6 39.4 21.5 22.7 33.1 109.1 21.6 16.6 22.3 23.5 23.6 17.2 40.4 15.0 21.9 23.5 28.0 23.2 30.9 21.3 26.6 66.2 18.2 18.8 16.7 22.1 16.7 20.0 16.8 22.7 21.0 34.3 84.8 20.5 23.9 15.2 24.5 31.2 18.9 69.8 22.4 59.8 57.8 53.0 25.3 51.3 44.6 35.3 35.1 37.2 37.8 40.9 37.3 26.3 29.7 34.2 44.0 35.3 32.3 17.3 26.6 26.5 36.3 46.9 48.6 32.6 84.7 51.0 60.0 38.6 35.8 32.2 51.4 40.8 27.9 50.0 17.8 37.0 15.8 50.3 38.6 48.2 45.7 34.4 45.5 45.8 61.8 23.2 38.3 98.3 49.5 37.4 71.3 48.1 48.2 24.8 26.5 31.1 29.9 30.1 42.5 57.9 68.6 43.1 20.9 38.9 9.1 5.5 5.0 5.8 8.9 4.2 5.0 2.8 3.5 5.5 1.9 4.0 3.7 2.2 4.7 6.6 3.4 4.2 2.3 21.1 22.5 22.2 23.5 21.5 22.7 22.3 23.5 23.5 22.1 22.7 24.5 16.4 9.6 20.6 9.1 12.7 9.9 21.0 15.4 13.1 18.8 18.9 16.4 45.6 20.0 11.3 16.5 10.4 30.0 6.9 25.4 49.0 22.6 6.6 12.0 13.7 13.6 11.4 15.6 8.6 14.8 51.2 18.4 13.3 12.0 16.5 15.6 20.0 60.1 30.1 25.2 9.0 11.5 0.0 15.7 7.0 3.1 21.8 15.0 21.4 6.5 24.9 39.0 12.3 6.0 11.5 20.2 17.2 29.3 9.5 18.5 29.8 40.7 11.8 12.7 32.9 14.6 16.2 17.8 25.3 15.0 9.9 38.7 12.5 18.2 15.7 25.2 PFDN5 "MM-1, PFD5" ENSG00000123349 "Prefoldin subunit 5" Q99471 12 53295291-53299452 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 3559.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA008587 Approved Supported "Intermediate filaments,Cytosol" NA NA 110000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 32: Non-specific - Translation" "Intermediate filaments, Cytosol" "HPA008587: AB_1079597" "unprognostic (3.56e-3)" "unprognostic (2.31e-2)" "unprognostic (2.87e-2)" "unprognostic (4.02e-3)" "unprognostic (1.59e-1)" "unprognostic (3.44e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-2)" "unprognostic (2.65e-2)" "unprognostic (2.12e-1)" "prognostic favorable (5.45e-4)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.34e-2)" "unprognostic (9.48e-2)" "unprognostic (2.30e-2)" "unprognostic (2.01e-3)" 719.5 656.4 903.9 307.4 919.3 863.9 819.2 894.2 1279.0 907.5 890.8 684.3 238.6 555.3 867.4 520.1 654.0 366.1 633.1 880.3 907.3 677.4 505.6 539.2 610.5 907.4 899.1 1007.6 724.5 606.1 688.1 399.6 910.7 671.6 371.8 371.8 557.5 394.2 723.2 684.8 514.0 357.2 935.9 712.7 591.9 388.0 927.2 547.7 634.5 615.5 625.9 614.7 651.4 928.1 333.3 492.3 472.8 426.6 889.1 1220.7 347.2 814.5 1081.9 730.8 489.3 456.0 496.9 449.2 479.3 871.1 285.7 299.0 416.7 575.0 702.6 425.4 575.7 410.6 639.1 634.6 574.3 676.8 425.6 1174.9 823.4 522.7 398.6 1269.3 658.4 539.4 485.7 589.1 735.3 1150.9 478.1 993.0 447.7 359.1 757.4 381.1 514.6 530.8 842.9 477.8 396.5 454.1 525.6 450.1 612.1 481.8 588.1 843.6 585.6 408.2 319.1 198.7 372.6 444.5 500.8 670.7 450.3 528.5 386.0 1641.6 2761.6 989.6 1636.2 2095.6 2283.3 3705.2 2468.1 2003.4 2060.9 3368.6 3147.1 2533.0 740.8 1645.0 2221.2 1921.0 2149.1 8653.7 903.9 919.3 894.2 1279.0 880.3 907.3 907.4 899.1 910.7 935.9 927.2 928.1 711.6 262.8 501.5 27.7 1274.1 1505.2 1217.7 1648.8 900.3 184.0 1219.6 1850.4 598.0 684.9 778.6 566.4 102.2 899.8 862.2 593.0 1412.6 561.2 902.9 629.9 703.6 734.7 659.9 587.9 25.3 961.0 973.4 708.4 362.9 440.2 655.9 647.4 782.8 584.8 1830.1 72.3 25.0 892.0 734.5 1977.7 2549.4 3559.9 948.7 1235.9 1538.5 15.9 1663.4 619.2 905.3 21.6 27.6 705.6 990.6 655.2 582.9 971.9 1053.0 2024.3 862.7 321.5 552.2 713.6 902.4 469.7 234.3 762.4 1526.5 876.0 1147.0 658.2 849.4 1114.8 PFKFB1 PFRX ENSG00000158571 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1" P16118 X 54932961-54998534 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adipose tissue: 28.3;liver: 50.2;skeletal muscle: 111.6;tongue: 40.8" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 15.9" "Cancer enriched" "Detected in some" 11 "liver cancer: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 8.5;Hep G2: 3.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.51e-1)" "unprognostic (2.39e-2)" "unprognostic (1.17e-2)" "unprognostic (4.38e-3)" "unprognostic (1.64e-1)" "unprognostic (6.12e-2)" "unprognostic (1.18e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "unprognostic (3.33e-1)" "unprognostic (3.26e-3)" "unprognostic (2.88e-1)" "unprognostic (5.36e-3)" "unprognostic (5.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.16e-4)" "unprognostic (1.96e-3)" 28.3 0.5 0.4 0.1 0.5 0.4 9.2 0.3 0.5 0.1 0.1 0.4 0.1 0.1 0.6 1.1 0.1 0.3 0.3 0.4 0.4 1.1 50.2 0.2 0.5 0.5 0.4 0.0 1.2 0.3 0.5 0.2 0.4 0.3 0.5 0.4 0.7 0.2 111.6 0.8 0.5 0.1 0.4 0.3 0.4 0.4 0.4 0.4 1.0 40.8 0.6 0.2 0.2 0.5 0.2 0.1 0.2 0.4 8.5 0.1 0.6 0.0 0.1 0.1 0.0 0.5 0.1 0.4 0.1 0.0 0.4 0.3 0.1 0.2 0.3 0.3 0.7 0.2 0.1 3.2 0.0 0.0 0.3 0.1 0.4 0.0 0.2 0.0 0.0 0.8 0.1 1.4 0.1 0.5 0.4 0.2 0.2 0.2 0.2 0.3 0.1 0.1 0.0 0.2 0.2 0.1 0.3 1.0 0.1 0.7 0.2 0.0 0.1 0.1 0.3 0.2 0.1 0.7 1.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.5 0.4 0.4 0.5 0.4 0.4 0.4 0.4 0.5 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 15.9 0.1 0.0 1.5 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.3 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 PFN4 ENSG00000176732 "Profilin family member 4" Q8NHR9 2 24114809-24123464 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 27 "testis: 81.1" "Group enriched" "Detected in some" 6 "Early spermatids: 491.1;Spermatocytes: 319.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (4.20e-3)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (3.52e-2)" "unprognostic (1.37e-1)" "unprognostic (4.56e-4)" "unprognostic (1.25e-1)" "unprognostic (3.82e-2)" "unprognostic (2.21e-2)" "unprognostic (2.74e-2)" "unprognostic (8.97e-3)" "unprognostic (1.77e-5)" "unprognostic (2.55e-2)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" "unprognostic (9.10e-2)" 0.8 0.6 1.6 0.2 1.2 0.2 1.3 1.4 1.7 0.7 1.2 0.4 0.2 0.9 2.0 0.8 1.7 0.6 1.2 1.0 1.1 1.2 0.3 0.8 0.5 1.0 1.2 1.8 0.4 1.0 1.2 0.5 1.1 0.8 0.6 3.0 0.7 0.7 1.0 0.6 0.4 0.4 0.7 0.7 0.3 81.1 1.1 0.4 1.9 0.5 0.7 0.4 0.6 1.3 2.0 1.0 0.4 1.8 1.9 1.9 0.7 0.6 0.3 0.6 0.4 0.4 2.1 1.2 0.3 0.0 2.3 0.2 0.0 0.2 0.2 1.5 0.0 0.1 0.5 0.0 1.1 0.3 0.1 2.4 1.2 0.5 1.2 0.4 0.3 1.3 0.4 1.1 1.0 1.4 0.3 0.6 0.4 0.0 1.3 0.4 1.0 0.0 1.0 0.2 1.1 1.6 0.7 0.2 0.6 0.7 2.1 0.4 0.9 0.9 0.7 0.1 0.7 1.7 1.7 1.1 1.6 0.1 1.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 1.6 1.2 1.4 1.7 1.0 1.1 1.0 1.2 1.1 0.7 1.1 1.3 0.3 0.0 1.1 0.7 0.2 0.3 0.6 0.4 0.0 0.8 0.9 0.6 2.4 0.0 0.3 0.0 0.0 0.4 0.2 0.1 3.9 0.5 491.1 4.6 0.9 1.1 0.0 0.0 1.3 1.4 0.7 0.7 0.0 0.7 0.0 1.7 0.4 0.8 1.0 1.7 1.7 0.2 0.0 0.0 0.0 66.9 6.5 0.7 0.0 0.0 0.0 1.1 0.0 0.5 1.4 0.8 0.0 1.9 0.1 0.3 0.1 2.0 4.3 1.0 0.0 0.5 0.5 319.1 3.6 0.0 0.6 0.3 0.1 0.8 0.2 0.4 PGBD4 "FLJ32638, FLJ37497" ENSG00000182405 "PiggyBac transposable element derived 4" Q96DM1 15 34102083-34108686 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.9" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.9" "Low cell line specificity" "Detected in many" "HPA040896, HPA059823" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 34: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Nucleoplasm Centrosome "HPA040896: AB_10805831, HPA059823: AB_2684134" "unprognostic (9.54e-2)" "unprognostic (2.29e-1)" "unprognostic (1.45e-2)" "unprognostic (3.51e-2)" "unprognostic (7.43e-3)" "unprognostic (2.61e-2)" "unprognostic (1.10e-1)" "unprognostic (2.35e-2)" "unprognostic (6.47e-2)" "unprognostic (6.66e-2)" "unprognostic (1.32e-3)" "unprognostic (9.70e-2)" "unprognostic (6.68e-2)" "unprognostic (2.14e-2)" "unprognostic (8.54e-2)" "unprognostic (3.15e-2)" "unprognostic (7.73e-2)" 0.8 0.8 2.5 1.6 2.4 2.8 1.1 3.1 3.2 0.6 2.2 0.9 1.1 0.7 1.3 0.8 1.1 0.7 1.5 2.4 2.6 1.1 1.3 0.7 2.0 3.5 2.4 0.9 1.0 1.5 0.6 0.6 3.5 0.9 1.1 2.4 0.7 0.8 5.3 1.6 1.1 0.6 1.9 1.4 1.4 1.8 2.4 1.3 1.1 1.3 1.5 0.6 0.6 3.1 1.0 1.9 1.3 2.2 3.9 2.5 0.8 1.7 1.6 1.0 1.3 1.3 1.4 2.2 1.3 1.3 2.1 3.0 0.8 1.9 1.3 2.4 2.0 3.7 4.2 1.0 1.6 1.2 3.2 1.9 2.2 1.4 2.5 1.8 1.1 4.1 2.6 2.6 2.2 0.8 2.1 2.9 0.5 2.2 1.4 3.1 1.8 1.1 1.4 2.3 1.9 1.7 0.8 1.9 0.6 1.6 1.8 1.9 1.3 3.2 1.8 1.7 1.1 3.1 2.1 1.2 2.8 2.9 1.9 3.9 0.5 0.6 0.4 0.4 0.3 0.5 0.6 0.4 0.3 0.9 0.9 0.8 1.1 0.6 0.3 0.6 0.5 0.2 2.5 2.4 3.1 3.2 2.4 2.6 3.5 2.4 3.5 1.9 2.4 3.1 1.4 0.0 3.2 2.0 4.1 0.8 2.5 1.8 3.4 5.6 1.9 1.3 5.8 2.8 2.9 0.0 6.2 2.0 5.6 3.1 9.8 1.2 11.6 2.0 3.8 2.1 0.0 2.5 2.7 0.7 0.6 1.8 3.6 2.3 1.3 1.8 3.6 2.2 1.3 10.1 3.1 2.5 4.1 2.8 0.4 11.5 1.2 2.2 0.0 1.0 2.1 2.1 3.1 2.0 3.9 2.1 2.5 0.4 1.6 2.0 3.6 1.4 3.9 6.9 13.1 3.9 1.9 7.6 1.6 2.3 0.3 3.3 4.6 2.7 2.9 1.5 PGRMC2 "DG6, PMBP" ENSG00000164040 "Progesterone receptor membrane component 2" O15173 4 128269237-128288829 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041172, HPA058652" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 76000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Nuclear bodies, Plasma membrane, Cytosol" "HPA041172: AB_2677345, HPA058652: AB_2683786" "unprognostic (6.16e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-2)" "prognostic favorable (3.62e-4)" "unprognostic (6.03e-2)" "unprognostic (6.57e-3)" "unprognostic (2.53e-2)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (8.24e-2)" "unprognostic (9.04e-2)" "unprognostic (3.80e-2)" "prognostic favorable (9.60e-4)" "unprognostic (3.12e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-2)" "unprognostic (6.03e-2)" 107.3 51.9 23.8 38.1 25.6 41.7 76.6 25.8 29.8 58.4 34.1 68.1 127.3 52.3 51.3 57.5 44.2 53.4 50.7 25.0 30.2 96.0 173.8 42.7 30.6 25.6 29.6 57.9 74.2 80.5 49.0 85.3 27.7 53.0 65.2 55.1 55.3 73.2 54.4 98.2 121.9 67.4 26.6 32.5 95.8 39.5 28.5 28.0 65.6 44.0 40.8 56.3 51.0 29.8 123.3 44.4 80.3 64.9 339.8 177.6 80.5 164.6 182.7 119.4 158.3 46.4 123.6 86.3 187.8 213.4 138.8 70.1 74.3 81.6 149.3 49.7 42.7 58.0 111.3 88.3 429.1 84.7 41.7 140.9 161.3 100.3 123.3 277.0 109.1 55.0 98.2 105.6 173.7 38.2 78.9 39.2 63.1 148.5 39.7 62.5 64.2 59.8 176.8 42.9 63.3 59.7 92.4 103.1 97.3 131.2 79.7 38.0 203.5 100.0 81.4 103.8 77.3 121.0 106.0 91.3 109.9 74.4 70.1 2.2 1.0 2.0 1.5 0.9 0.7 1.2 1.8 1.5 0.6 0.9 1.6 1.5 0.9 1.1 0.7 2.4 2.0 0.6 23.8 25.6 25.8 29.8 25.0 30.2 25.6 29.6 27.7 26.6 28.5 29.8 95.9 54.5 41.0 16.6 27.0 100.1 49.7 27.8 54.1 22.4 49.2 32.8 60.7 58.6 35.9 44.1 10.4 85.4 41.2 68.2 29.4 57.3 80.9 42.2 59.1 50.0 35.5 104.2 20.4 74.2 146.6 69.9 53.0 64.2 12.0 31.0 47.2 125.1 35.3 11.8 19.1 67.8 40.7 15.7 39.5 49.5 46.3 22.1 67.6 13.1 19.0 98.6 21.6 13.6 25.0 69.7 50.6 37.6 48.9 58.0 177.3 111.0 27.4 41.1 13.1 63.3 53.1 33.3 27.3 51.9 111.8 274.9 32.4 39.4 58.8 34.4 PHETA2 "DKFZp686J07229, FAM109B, IPIP27B, SES2" ENSG00000177096 "PH domain containing endocytic trafficking adaptor 2" Q6ICB4 22 42074248-42079438 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 14.1;Endometrial stromal cells: 10.3;Extravillous trophoblasts: 27.4;Syncytiotrophoblasts: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 20.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 36.8;fHDF/TERT166: 33.7;HSkMC: 32.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA000647 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA000647: AB_1078800" "unprognostic (4.96e-2)" "unprognostic (3.28e-2)" "unprognostic (5.90e-2)" "unprognostic (6.66e-3)" "unprognostic (1.56e-2)" "unprognostic (9.61e-3)" "unprognostic (2.40e-1)" "unprognostic (1.19e-1)" "unprognostic (2.31e-1)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (8.80e-2)" "unprognostic (7.52e-2)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (2.81e-2)" "unprognostic (4.03e-2)" 11.1 4.3 2.8 6.6 2.7 4.6 9.7 2.5 2.8 12.2 4.3 11.4 6.0 15.4 2.8 9.6 9.8 8.2 8.5 2.5 2.8 7.1 1.9 9.7 4.1 3.1 2.7 5.2 18.2 4.8 5.8 15.6 2.8 9.9 8.5 0.4 12.7 7.6 2.5 8.3 9.4 12.9 3.1 7.8 13.4 2.5 2.8 2.4 5.8 3.1 4.2 11.3 9.1 2.8 0.1 0.0 0.0 0.2 30.9 36.8 0.2 21.4 17.5 13.0 12.9 22.6 20.5 0.1 13.1 33.7 0.0 3.7 0.1 0.2 6.9 0.0 0.0 0.0 29.1 0.2 17.6 0.0 17.1 32.3 9.5 20.1 2.5 0.0 29.3 0.3 0.2 0.0 14.1 0.4 0.1 0.2 2.4 1.1 0.0 0.2 0.1 0.3 5.9 0.0 0.2 0.2 9.2 0.1 0.1 0.2 14.1 0.0 30.0 0.2 13.8 31.5 0.1 0.5 0.5 0.3 0.0 0.4 24.0 20.0 4.3 1.7 1.3 4.9 0.2 0.5 0.8 1.0 8.4 0.2 0.6 1.2 0.3 0.7 2.8 3.9 0.6 3.2 2.8 2.7 2.5 2.8 2.5 2.8 3.1 2.7 2.8 3.1 2.8 2.8 4.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 2.4 0.0 0.0 0.0 0.0 0.0 14.1 0.2 0.0 3.9 5.7 0.0 1.1 10.3 3.0 0.0 0.0 0.0 7.0 27.4 6.6 0.0 2.8 0.0 3.8 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 2.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 22.2 0.2 3.6 0.0 0.0 PHLDB1 "FLJ00141, KIAA0638, LL5a" ENSG00000019144 "Pleckstrin homology like domain family B member 1" Q86UU1 11 118606440-118658031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 87.2;Late spermatids: 87.7;Oligodendrocytes: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 105.2;ASC TERT1: 105.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037959, HPA038448" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA No "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Cytosol" "Plasma membrane" "HPA037959: AB_10673651, HPA038448: AB_10697390" "unprognostic (7.81e-2)" "unprognostic (8.32e-3)" "unprognostic (1.13e-1)" "unprognostic (9.36e-3)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" "unprognostic (4.37e-3)" "unprognostic (1.22e-1)" "unprognostic (3.21e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.36e-6)" "unprognostic (7.09e-2)" "unprognostic (2.42e-2)" "unprognostic (3.69e-2)" "unprognostic (1.44e-1)" 52.6 8.1 39.2 11.5 79.7 0.5 38.9 42.5 66.0 39.1 3.8 23.8 9.2 38.4 2.6 9.1 30.2 21.6 33.0 42.3 49.2 15.8 3.2 26.8 4.6 64.3 64.6 31.9 22.2 4.5 8.8 24.6 56.0 16.7 6.4 1.6 11.1 15.8 13.3 15.1 15.3 18.6 33.4 12.5 14.3 12.0 75.3 3.1 20.3 13.6 2.3 21.9 22.9 133.7 4.8 7.5 28.9 14.2 105.2 105.9 10.1 21.9 26.6 12.7 7.4 11.2 31.8 0.0 40.2 44.3 17.2 18.6 6.6 44.8 2.0 0.7 4.2 8.6 5.7 5.5 27.2 0.0 15.8 55.8 9.6 17.8 12.5 28.3 36.6 0.7 7.5 0.3 16.7 3.4 0.1 0.5 10.2 0.4 3.8 1.1 7.5 0.7 12.5 6.8 6.5 14.5 55.8 4.7 15.6 11.3 20.1 2.7 45.4 25.9 22.9 13.2 18.3 0.2 0.0 0.1 7.5 1.5 29.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 39.2 79.7 42.5 66.0 42.3 49.2 64.3 64.6 56.0 33.4 75.3 133.7 34.4 6.4 13.7 53.2 1.6 18.4 9.2 13.7 14.2 4.0 7.2 19.6 5.6 1.5 6.3 31.3 0.0 1.0 2.5 34.2 0.0 9.4 78.3 11.6 87.2 32.1 8.4 0.0 4.1 4.4 1.5 54.9 11.7 8.6 1.3 25.6 26.4 0.9 5.9 3.3 8.3 20.4 0.0 2.5 34.4 87.7 67.1 8.2 12.4 23.4 2.2 7.6 0.0 67.3 244.5 24.3 29.8 44.4 0.7 4.2 10.7 7.8 0.5 2.3 39.5 42.9 53.8 21.9 10.1 1.9 9.1 1.5 5.4 11.0 16.8 2.4 PHYH "PAHX, PHYH1, RD" ENSG00000107537 "Phytanoyl-CoA 2-hydroxylase" O14832 10 13277796-13302412 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 667.8;skeletal muscle: 483.6;tongue: 412.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 258.6;Proximal tubular cells: 414.6" "Cancer enhanced" "Detected in all" "liver cancer: 78.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007598, HPA011796" Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA007598: AB_1855334, HPA011796: AB_1855335" "unprognostic (5.78e-2)" "unprognostic (3.83e-1)" "unprognostic (6.98e-2)" "unprognostic (3.62e-2)" "unprognostic (5.52e-2)" "unprognostic (1.61e-3)" "unprognostic (1.16e-1)" "unprognostic (1.95e-2)" "unprognostic (7.09e-2)" "unprognostic (6.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.24e-1)" "prognostic favorable (7.28e-12)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.19e-1)" 57.9 66.5 22.9 9.5 23.7 8.2 32.2 23.5 28.3 28.8 31.7 46.5 58.7 22.1 16.7 22.9 16.7 28.2 126.5 21.7 24.1 191.4 667.8 17.3 7.5 21.6 24.4 36.8 48.2 56.7 20.9 19.3 22.8 22.5 37.2 28.2 33.7 25.4 483.6 17.5 55.8 23.2 22.7 12.8 44.2 15.1 26.0 5.6 56.0 412.7 5.4 27.0 14.8 23.6 17.2 35.2 15.6 22.5 110.7 69.9 12.4 17.2 23.9 19.4 19.1 9.1 30.3 0.9 12.9 29.0 47.0 7.8 20.5 20.2 11.8 41.4 10.7 14.9 9.3 36.6 54.8 2.5 26.8 50.3 28.9 21.0 8.4 22.7 18.7 16.8 8.4 32.2 45.5 16.3 9.2 12.1 14.4 49.4 12.6 15.7 24.1 5.8 40.6 21.9 5.3 16.8 64.8 1.4 32.9 12.5 64.8 44.2 6.4 29.5 10.6 36.4 11.8 36.6 26.3 3.3 38.3 18.9 11.6 16.3 18.7 8.2 8.0 14.2 17.6 11.0 9.9 10.4 15.8 5.6 12.5 12.7 0.8 4.4 11.2 14.4 10.5 12.3 22.9 23.7 23.5 28.3 21.7 24.1 21.6 24.4 22.8 22.7 26.0 23.6 53.6 12.8 19.2 8.5 14.5 11.9 27.6 19.1 6.2 47.0 22.6 24.5 258.6 77.2 19.7 35.0 22.9 137.8 20.5 72.9 144.8 40.6 33.1 18.5 29.0 29.7 31.8 15.2 7.1 19.6 34.3 41.3 41.8 26.8 30.4 28.3 25.0 145.5 55.4 21.9 5.6 57.4 46.8 21.0 22.0 45.4 25.4 25.3 17.8 4.7 10.3 69.3 7.2 2.5 2.4 16.7 46.0 37.6 15.1 11.9 141.9 414.6 19.6 41.8 19.7 30.2 37.5 12.5 1.6 7.3 13.4 83.9 25.2 103.3 46.9 18.1 PIGK "GPI8, hGPI8" ENSG00000142892 "Phosphatidylinositol glycan anchor biosynthesis class K" Q92643 1 77088989-77219430 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Hydrolase, Protease, Thiol protease" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056383, HPA057040" Uncertain "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA056383: AB_2683109, HPA057040: AB_2683319" "unprognostic (2.43e-2)" "unprognostic (2.60e-1)" "unprognostic (4.07e-2)" "unprognostic (2.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (4.68e-4)" "unprognostic (1.07e-1)" "unprognostic (5.19e-1)" "unprognostic (1.12e-1)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (1.76e-2)" "unprognostic (3.37e-1)" "unprognostic (1.38e-1)" "unprognostic (1.21e-1)" "unprognostic (8.12e-3)" 9.8 12.4 5.2 6.3 6.6 8.8 12.4 6.1 9.4 9.7 5.7 8.5 6.9 9.5 9.7 6.5 9.3 10.0 14.1 6.0 6.4 17.7 13.2 9.2 8.8 5.9 5.5 9.6 9.6 16.3 6.5 6.4 6.2 11.2 9.3 9.8 9.5 8.8 7.0 4.8 7.3 10.7 6.8 9.8 8.9 6.0 5.5 8.5 16.3 9.8 7.5 9.3 4.2 9.8 12.3 14.2 11.5 14.7 64.1 48.1 18.6 24.4 33.1 25.0 35.6 11.8 12.2 10.7 24.4 43.1 29.7 10.8 14.8 20.8 45.2 22.1 15.1 14.6 13.8 11.1 14.4 32.5 12.4 29.2 11.1 26.7 22.9 29.9 37.4 13.2 18.0 35.6 39.0 8.3 10.3 13.2 10.4 13.7 23.4 12.0 33.7 13.3 31.9 8.9 9.7 9.1 23.2 20.8 27.1 18.9 10.0 18.5 21.5 40.1 15.6 21.9 25.0 16.1 23.7 10.7 29.8 40.5 16.2 7.2 3.0 5.8 5.8 3.4 6.0 3.7 6.0 5.0 5.7 3.2 7.5 6.8 1.5 7.4 3.5 3.9 9.8 4.7 5.2 6.6 6.1 9.4 6.0 6.4 5.9 5.5 6.2 6.8 5.5 9.8 17.7 9.6 9.1 16.3 14.4 9.6 15.2 23.7 5.2 14.2 21.0 14.2 23.0 18.6 18.3 40.5 2.1 16.0 14.1 9.7 3.9 20.8 2.1 15.6 15.5 18.1 10.8 16.4 51.4 21.1 35.7 29.3 6.6 14.1 17.7 14.7 20.3 29.3 20.3 8.4 40.2 12.4 24.4 14.5 13.9 3.7 19.6 11.9 19.6 26.2 9.2 17.6 18.6 40.7 78.2 11.9 8.5 27.4 41.7 10.1 9.3 23.3 25.3 12.4 52.6 16.3 24.1 75.8 30.2 9.4 11.9 15.2 15.5 12.7 12.7 11.5 PIK3C3 Vps34 ENSG00000078142 "Phosphatidylinositol 3-kinase catalytic subunit type 3" Q8NEB9 18 41955234-42087830 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 114.9;Inhibitory neurons: 104.1;Oligodendrocytes: 115.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040718 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA040718: AB_10793862" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.40e-2)" "unprognostic (3.55e-3)" "unprognostic (6.15e-2)" "unprognostic (3.61e-2)" "unprognostic (6.00e-3)" "unprognostic (1.91e-1)" "unprognostic (2.11e-1)" "unprognostic (1.71e-2)" "unprognostic (3.86e-2)" "unprognostic (6.41e-2)" "prognostic favorable (4.97e-4)" "unprognostic (1.09e-1)" "unprognostic (1.35e-2)" "unprognostic (1.76e-1)" "unprognostic (6.85e-3)" 10.9 16.1 6.8 12.0 10.0 15.9 16.4 18.2 11.5 13.2 12.7 11.7 8.9 15.0 16.6 11.8 12.2 12.1 11.5 7.3 7.8 16.2 14.3 11.7 14.1 8.3 7.0 17.0 9.0 18.6 8.0 17.2 9.9 12.8 13.7 16.7 10.9 12.5 12.2 11.4 10.6 13.9 8.7 13.3 11.5 18.0 7.6 18.5 15.3 16.2 15.8 15.1 9.9 12.9 16.2 11.3 27.8 21.3 31.6 33.8 17.1 31.4 39.8 24.7 33.2 5.4 8.0 10.0 17.6 31.8 19.4 26.0 22.1 17.5 34.2 16.3 15.5 20.8 15.4 21.7 26.3 30.9 22.1 37.3 25.8 23.2 29.9 37.9 25.6 19.9 20.9 12.2 34.3 5.3 13.6 19.8 20.4 6.0 8.1 81.9 21.0 26.1 28.3 17.1 24.2 28.1 10.2 7.3 22.2 30.8 10.8 24.8 33.7 33.3 9.7 7.4 14.6 33.3 42.2 11.3 27.5 41.4 18.0 20.5 9.9 21.2 9.2 11.0 10.3 11.4 9.3 11.5 10.2 10.1 11.8 8.9 19.2 12.1 12.5 5.8 17.0 8.2 6.8 10.0 18.2 11.5 7.3 7.8 8.3 7.0 9.9 8.7 7.6 12.9 22.4 22.4 36.9 70.2 21.1 11.5 10.8 15.3 15.4 28.2 11.5 11.0 23.5 4.3 27.3 14.7 20.9 20.6 26.8 13.8 7.9 14.4 28.6 16.9 22.4 19.9 4.9 19.1 114.9 10.3 13.3 22.4 13.7 18.3 17.1 25.4 17.2 13.4 15.6 55.5 104.1 11.5 16.2 17.9 10.1 13.2 14.6 20.9 7.2 58.1 21.5 26.2 13.4 83.4 115.6 14.3 10.0 24.0 18.2 14.5 12.9 12.3 22.4 22.5 19.7 25.4 18.9 20.0 18.6 14.3 11.4 27.4 23.8 24.7 10.6 15.9 PIK3R1 "GRB1, p85, p85-ALPHA" ENSG00000145675 "Phosphoinositide-3-kinase regulatory subunit 1" P27986 5 68215756-68301821 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Protein transport, Stress response, Transport" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "dendritic cells: 410.2;Endometrial stromal cells: 479.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 265.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001216, CAB004268" Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB004268: AB_628126, HPA001216: AB_1079612" "unprognostic (5.74e-2)" "unprognostic (6.58e-2)" "unprognostic (2.01e-1)" "unprognostic (1.31e-2)" "unprognostic (1.18e-1)" "unprognostic (1.33e-2)" "prognostic favorable (8.09e-4)" "unprognostic (3.78e-3)" "unprognostic (1.78e-1)" "unprognostic (2.71e-1)" "unprognostic (6.10e-2)" "unprognostic (1.32e-1)" "unprognostic (4.59e-3)" "unprognostic (5.66e-3)" "unprognostic (1.27e-1)" "unprognostic (5.92e-2)" "unprognostic (1.54e-1)" 60.6 27.3 13.6 27.8 33.3 126.4 92.1 12.5 40.8 51.2 0.6 38.2 17.2 65.8 45.0 43.2 69.0 35.0 72.3 29.9 13.0 35.9 100.8 26.7 28.5 11.2 22.1 53.3 13.4 40.2 7.3 32.4 12.0 26.7 22.2 59.9 64.5 31.9 63.5 28.7 24.5 74.8 9.9 38.1 18.3 8.6 20.3 46.5 20.6 33.9 23.7 27.0 31.7 36.0 4.3 8.2 23.8 71.4 265.5 76.9 10.4 23.2 10.6 8.8 9.4 20.4 7.4 21.8 38.5 32.0 4.3 10.2 6.7 46.9 11.0 90.6 8.9 26.1 6.5 17.0 89.2 27.0 20.1 81.9 104.2 16.1 83.6 4.1 11.7 25.0 4.1 16.1 8.1 11.3 65.7 10.5 6.9 14.7 4.3 61.1 11.3 17.0 11.5 47.9 4.7 21.3 4.0 6.3 15.0 13.7 34.3 19.0 14.0 10.3 10.4 17.3 14.8 18.0 29.2 25.2 11.1 32.9 7.8 22.0 1.7 8.8 11.5 2.4 16.6 1.7 14.9 11.1 3.0 3.9 18.6 14.1 2.2 11.7 6.5 1.2 12.3 5.5 13.6 33.3 12.5 40.8 29.9 13.0 11.2 22.1 12.0 9.9 20.3 36.0 47.7 51.3 24.8 112.3 47.7 14.4 23.5 30.8 175.2 46.0 61.4 168.4 263.0 38.6 19.3 5.5 25.0 13.4 410.2 28.4 72.4 15.8 12.6 38.7 479.9 39.0 9.6 43.5 232.8 9.5 18.5 151.0 43.8 93.2 68.9 110.4 31.1 198.3 30.7 48.8 82.7 32.6 28.5 69.2 24.7 11.9 172.1 68.8 33.8 117.1 37.6 194.1 137.0 281.5 199.9 12.3 19.8 122.2 173.2 8.4 24.3 39.1 8.7 89.4 19.7 127.2 76.5 1.7 4.5 37.2 10.2 10.0 309.9 45.4 36.5 8.1 PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 124.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 926.5;Leydig cells: 873.5;Peritubular cells: 659.7;Sertoli cells: 295.9;Smooth muscle cells: 446.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 98.5;ASC TERT1: 85.3;BEWO: 32.1;HSkMC: 28.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 37.9" HPA043469 Uncertain "Secreted - unknown location" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043469: AB_10795770" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (1.78e-2)" "unprognostic (2.76e-1)" "unprognostic (3.93e-1)" "unprognostic (5.57e-3)" "unprognostic (5.88e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-3)" 112.3 18.4 10.2 6.6 9.2 1.2 85.7 10.3 15.5 77.3 53.3 22.1 4.0 26.9 5.0 21.4 30.4 9.0 124.3 14.3 5.9 17.9 6.4 56.1 2.7 5.9 5.8 11.5 5.7 4.1 4.9 12.5 6.4 35.9 4.6 0.6 20.1 7.6 16.9 47.8 19.7 6.5 6.5 5.0 21.4 14.9 6.9 2.2 44.6 19.2 1.9 54.0 75.7 8.5 0.2 0.0 0.8 0.0 98.5 85.3 32.1 10.3 8.7 0.9 1.2 0.0 0.7 0.0 0.2 6.0 0.1 0.8 0.1 0.0 0.0 0.8 0.3 0.0 0.5 0.0 16.4 0.0 2.3 28.7 0.0 2.1 1.2 10.6 3.4 0.4 0.0 0.4 0.0 0.3 0.1 0.6 1.9 0.4 1.5 0.0 0.1 1.5 0.0 0.6 0.0 1.8 0.0 1.2 0.7 0.2 0.1 0.2 3.6 6.6 3.6 21.0 0.2 0.7 0.9 0.1 1.9 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 10.2 9.2 10.3 15.5 14.3 5.9 5.9 5.8 6.4 6.5 6.9 8.5 246.2 3.2 1.8 0.0 1.6 126.4 0.7 1.1 8.0 0.4 7.4 14.0 24.4 0.0 0.3 0.0 0.0 7.0 3.6 0.1 0.0 0.3 4.6 3.1 75.7 102.5 1.8 0.0 0.5 0.2 17.7 926.5 5.6 4.4 1.3 0.1 115.6 0.3 14.1 0.0 0.5 0.0 0.0 0.0 191.3 26.7 873.5 7.9 136.9 7.5 0.0 50.2 0.0 0.0 0.2 0.7 0.0 659.7 2.1 1.0 0.0 0.2 0.9 1.7 295.9 89.7 446.6 2.6 2.9 4.6 126.3 11.5 14.1 1.1 0.0 1.8 PLAG1 ZNF912 ENSG00000181690 "PLAG1 zinc finger" Q6DJT9 8 56160909-56211324 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 32.0;Microglial cells: 28.1;Rod photoreceptor cells: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 16.0;ASC TERT1: 20.9;hTERT-HME1: 15.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072290 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA072290: AB_2686508" "unprognostic (1.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-3)" "unprognostic (1.63e-4)" "unprognostic (6.81e-2)" "unprognostic (1.07e-1)" "unprognostic (5.63e-3)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (7.99e-2)" "unprognostic (3.42e-2)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (2.83e-2)" "unprognostic (3.94e-1)" "unprognostic (1.21e-2)" "unprognostic (6.14e-2)" 0.7 1.4 0.8 1.0 1.2 0.9 0.9 2.5 1.1 3.0 0.6 0.8 1.4 1.4 4.1 0.7 3.1 0.7 3.1 0.7 1.0 1.3 0.3 1.9 1.8 1.5 1.4 4.9 0.8 1.2 3.8 1.6 1.8 1.3 0.6 7.7 3.0 1.8 0.4 1.4 2.3 0.4 1.2 2.6 1.3 2.4 1.3 2.8 1.3 1.4 2.3 1.3 3.0 2.0 2.0 0.0 11.9 0.1 16.0 20.9 3.7 5.4 6.9 2.5 1.1 0.8 6.2 0.2 5.1 2.9 0.7 0.4 3.4 7.1 2.5 0.2 7.4 8.0 0.8 1.8 3.3 2.5 2.3 14.9 3.9 1.4 15.6 6.9 4.7 5.3 3.4 0.1 5.3 0.1 0.7 4.7 3.4 0.5 1.8 6.1 0.8 4.9 3.2 0.7 0.1 0.0 0.1 0.1 0.4 8.0 0.1 2.4 7.2 3.6 4.6 5.9 1.4 1.8 1.5 2.9 4.1 0.9 1.0 0.6 0.0 0.4 0.1 0.0 0.1 1.3 0.4 0.2 0.0 0.7 1.8 1.8 0.4 0.3 0.2 0.1 0.1 0.4 0.8 1.2 2.5 1.1 0.7 1.0 1.5 1.4 1.8 1.2 1.3 2.0 2.6 6.4 3.2 2.9 13.0 1.0 2.5 6.2 1.8 23.6 1.6 0.6 12.2 4.3 6.7 5.5 25.0 8.3 2.0 1.0 0.0 0.7 6.2 3.0 2.3 3.7 5.4 5.0 16.8 1.3 4.2 4.0 2.6 4.2 1.3 0.4 15.7 0.7 5.8 32.0 12.3 3.6 6.1 2.9 2.2 6.7 15.2 2.8 16.0 28.1 1.2 16.3 4.1 2.0 19.2 1.4 4.1 10.1 6.3 5.0 5.1 0.8 9.1 27.8 0.0 2.4 1.4 9.0 8.8 1.1 0.9 7.1 4.5 0.9 3.6 12.9 PLBD2 p76 ENSG00000151176 "Phospholipase B domain containing 2" Q8NHP8 12 113358566-113391629 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 139.0" "Group enriched" "Detected in many" 5 "Early spermatids: 139.8;Late spermatids: 398.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 246.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017163 Approved "Intracellular and membrane" NA NA 820000 "Cluster 39: Non-specific - mRNA processing" "Cluster 43: Testis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA017163: AB_1853029" "unprognostic (8.28e-2)" "unprognostic (1.97e-1)" "unprognostic (1.50e-2)" "unprognostic (4.13e-1)" "unprognostic (2.36e-3)" "unprognostic (7.59e-3)" "unprognostic (5.92e-3)" "unprognostic (2.39e-2)" "unprognostic (2.35e-1)" "unprognostic (3.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.58e-11)" "unprognostic (7.55e-3)" "unprognostic (5.88e-2)" "unprognostic (1.09e-1)" "unprognostic (5.48e-2)" 26.7 139.0 23.6 16.7 21.3 9.0 16.4 31.0 30.3 20.5 5.7 12.9 8.1 19.7 25.9 12.6 13.9 20.2 31.7 23.2 33.4 11.8 23.3 20.9 10.8 47.4 35.2 48.6 26.1 17.5 27.2 12.8 44.7 17.9 12.8 13.0 17.9 15.9 23.8 19.1 11.4 27.1 26.9 13.5 13.2 50.7 40.9 5.8 18.0 14.3 10.8 20.5 15.4 24.5 20.1 36.2 15.4 58.6 246.3 136.9 20.9 41.6 82.0 28.8 35.7 30.9 11.8 9.3 34.0 113.1 46.9 21.3 14.9 24.6 32.0 19.0 10.9 16.4 21.5 37.3 76.9 19.8 49.3 115.8 32.0 34.6 20.5 87.4 45.4 8.3 49.9 22.1 44.9 34.1 3.7 21.2 17.1 16.2 16.6 15.8 16.2 25.0 33.8 27.7 15.5 15.3 57.3 44.6 25.5 26.5 29.4 18.8 73.5 67.9 26.3 68.9 24.4 11.8 21.9 11.4 112.3 16.5 40.6 0.0 3.5 0.2 1.2 2.1 1.0 0.4 1.4 1.5 3.5 0.4 1.0 1.4 0.3 0.9 1.5 1.3 0.9 2.0 23.6 21.3 31.0 30.3 23.2 33.4 47.4 35.2 44.7 26.9 40.9 24.5 6.5 9.6 6.4 11.8 5.3 5.4 4.6 2.1 5.7 9.8 5.4 4.3 10.0 5.7 1.4 1.8 6.2 4.6 6.4 3.6 0.0 20.5 139.8 2.6 13.5 7.0 5.3 13.9 12.4 13.8 11.1 29.5 6.6 5.8 10.2 13.3 8.2 16.1 32.5 20.2 14.2 2.9 0.0 25.8 8.4 398.5 40.4 27.0 21.4 3.7 39.4 3.1 4.1 9.0 11.8 11.5 3.4 48.2 5.9 6.4 6.4 5.0 2.2 5.2 6.6 10.7 11.3 11.1 8.1 6.2 1.8 4.4 5.3 33.6 4.0 3.7 PLEKHO2 "DKFZp761K2312, PLEKHQ1, PP1628, pp9099" ENSG00000241839 "Pleckstrin homology domain containing O2" Q8TD55 15 64841883-64868002 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 103.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 63.2;Kupffer cells: 52.3;Macrophages: 46.5;Muller glia cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 27.1;granulocytes: 77.3;monocytes: 73.0" "Cell line enhanced" "Detected in many" "ASC diff: 68.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040055 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 200000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA040055: AB_10793954" "unprognostic (4.32e-2)" "unprognostic (7.32e-3)" "unprognostic (8.60e-2)" "unprognostic (9.10e-2)" "unprognostic (1.11e-1)" "unprognostic (2.90e-2)" "unprognostic (3.05e-2)" "unprognostic (2.80e-1)" "unprognostic (7.70e-2)" "unprognostic (2.05e-2)" "unprognostic (8.67e-2)" "unprognostic (1.02e-1)" "unprognostic (3.08e-3)" "unprognostic (1.12e-1)" "unprognostic (4.20e-2)" "unprognostic (1.78e-1)" "unprognostic (5.85e-3)" 37.9 31.8 23.1 30.5 26.9 52.0 22.7 25.0 25.0 17.0 16.7 23.6 10.0 19.8 5.7 13.9 22.4 26.0 16.5 21.7 24.4 14.2 11.8 42.2 34.3 31.8 26.2 14.9 8.2 7.4 10.3 25.4 26.6 17.4 7.8 14.4 9.9 13.9 5.8 10.6 17.8 22.9 27.6 103.2 16.3 8.3 28.0 16.0 29.9 8.2 21.1 25.8 16.7 25.5 6.5 4.2 7.9 7.8 68.0 38.8 18.4 18.5 27.4 19.2 19.6 5.1 4.0 17.1 9.5 37.7 19.5 2.2 9.0 7.4 11.2 26.6 2.7 17.2 1.9 6.0 52.2 19.4 24.7 28.3 6.5 24.0 7.8 16.6 27.0 3.5 5.2 59.5 25.9 1.9 4.1 20.9 15.0 3.2 3.7 14.9 19.0 12.2 3.1 4.4 0.6 6.7 7.7 2.6 25.4 12.9 2.7 26.1 35.3 14.8 13.4 14.1 7.8 22.0 37.1 5.8 16.0 24.8 8.8 22.2 43.2 25.6 13.2 52.3 11.9 9.8 7.4 12.2 27.1 6.8 3.1 6.5 77.3 7.0 73.0 3.1 10.7 36.0 23.1 26.9 25.0 25.0 21.7 24.4 31.8 26.2 26.6 27.6 28.0 25.5 24.9 0.0 5.6 17.3 9.1 5.6 2.3 2.3 0.6 0.6 6.4 8.3 3.6 2.8 2.4 9.2 0.0 4.2 15.9 0.5 3.9 2.4 5.0 1.4 5.9 26.1 0.0 2.1 0.2 1.5 5.9 8.6 0.5 2.3 18.4 2.5 34.2 2.1 63.2 0.0 0.2 0.3 4.1 52.3 24.3 2.9 18.3 46.5 14.2 8.4 18.9 56.8 16.5 2.5 2.7 2.0 0.0 25.6 2.7 3.5 0.0 2.2 2.1 3.8 13.1 10.2 5.9 0.9 2.3 1.9 4.4 6.0 10.5 4.6 0.4 3.4 PLIN1 PLIN ENSG00000166819 "Perilipin 1" O60240 15 89664367-89679427 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "adipose tissue: 956.3;breast: 463.0" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 59.0" "Group enriched" "Detected in many" 5 "breast cancer: 8.4;liver cancer: 2.3;pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 171 "ASC diff: 208.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024299, CAB033821, CAB037333" Enhanced Uncertain Peroxisomes NA NA 22000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Peroxisomes "CAB033821: AB_2252681, CAB037333: , HPA024299: AB_1855467" "unprognostic (4.62e-2)" "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-1)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (9.89e-3)" "unprognostic (3.54e-1)" "unprognostic (7.01e-2)" "unprognostic (2.13e-2)" "unprognostic (8.00e-3)" "unprognostic (2.28e-3)" "unprognostic (2.62e-6)" "unprognostic (5.56e-2)" "unprognostic (1.22e-1)" "unprognostic (1.63e-1)" "unprognostic (4.85e-2)" 956.3 11.3 12.0 3.5 14.8 0.3 463.0 7.4 10.6 1.4 5.3 9.3 0.5 0.7 0.4 1.3 1.4 6.6 10.4 10.0 10.3 2.7 40.8 0.7 1.7 6.9 11.5 2.1 6.1 0.2 1.3 0.2 7.8 2.6 3.7 0.6 20.8 0.6 9.5 16.0 13.9 1.5 6.6 1.0 5.5 13.2 10.6 2.3 5.3 17.3 0.1 7.9 3.1 8.2 0.0 0.2 0.2 0.0 208.2 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.5 0.7 0.5 0.1 0.7 0.2 0.0 0.2 0.6 0.7 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.1 0.3 0.2 0.1 0.3 1.2 0.1 0.5 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.4 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 14.8 7.4 10.6 10.0 10.3 6.9 11.5 7.8 6.6 10.6 8.2 2.6 0.0 0.0 4.2 0.2 0.1 0.3 0.1 0.0 0.3 0.7 3.0 1.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 7.5 0.1 0.2 0.2 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.2 0.0 0.1 1.1 59.0 0.0 0.0 0.3 0.3 0.0 1.0 0.3 7.5 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.2 1.3 0.0 0.0 0.6 0.3 0.1 0.1 0.1 0.0 1.3 1.3 4.8 0.2 0.0 0.4 0.0 0.1 0.1 0.5 0.9 PLIN2 "ADFP, ADRP" ENSG00000147872 "Perilipin 2" Q99541 9 19108375-19149290 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 621.3;liver: 905.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 743.3;Hepatocytes: 527.0;Syncytiotrophoblasts: 1815.2" "Group enriched" "Detected in all" 5 "liver cancer: 63.0;renal cancer: 136.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 776.5;eosinophil: 581.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 776.5" "Group enriched" "Detected in many" 5 "ASC diff: 2345.1;HHSteC: 2025.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016607, CAB037331" Supported Supported "Lipid droplets" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Lipid droplets" "CAB037331: , HPA016607: AB_2669403" "unprognostic (2.02e-1)" "unprognostic (4.30e-2)" "unprognostic (3.47e-1)" "unprognostic (2.55e-2)" "unprognostic (2.41e-2)" "unprognostic (3.08e-2)" "unprognostic (3.02e-2)" "unprognostic (3.28e-3)" "unprognostic (4.92e-2)" "unprognostic (4.66e-2)" "unprognostic (1.40e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.32e-4)" "unprognostic (3.14e-3)" "unprognostic (7.89e-2)" "prognostic favorable (2.16e-4)" "unprognostic (1.77e-1)" 621.3 127.5 15.4 44.8 18.1 119.3 460.1 15.9 47.2 96.4 17.4 51.5 186.1 56.1 13.6 20.5 60.0 71.2 215.5 15.8 16.2 169.4 905.1 126.3 38.4 18.9 17.9 44.2 29.6 18.8 34.4 155.9 20.2 30.5 23.2 13.1 47.3 27.9 435.5 103.1 164.3 35.4 15.6 43.9 44.3 24.3 54.5 33.8 32.4 127.4 32.4 107.6 61.9 21.5 0.5 35.0 39.3 28.9 2345.1 318.3 434.8 113.5 87.6 67.7 76.5 54.1 8.3 0.4 2.0 232.9 432.1 4.7 39.1 0.3 115.1 146.9 0.8 191.8 5.4 205.2 2025.0 23.3 336.2 338.2 39.7 165.7 0.4 54.4 84.8 0.1 35.3 40.6 266.2 10.0 53.5 79.4 52.6 1.1 69.5 127.0 18.4 1.3 0.2 133.2 3.0 64.7 52.8 13.2 113.6 49.6 27.0 50.8 134.1 0.1 20.6 105.6 0.5 24.4 26.7 76.2 0.6 39.0 10.9 776.5 111.0 581.9 80.7 149.5 69.9 23.6 69.8 57.9 63.8 25.8 67.3 57.6 6.7 17.2 169.0 7.9 74.7 106.5 15.4 18.1 15.9 47.2 15.8 16.2 18.9 17.9 20.2 15.6 54.5 21.5 280.4 19.2 51.4 7.5 43.9 206.2 507.2 69.5 42.1 2.4 213.3 24.1 62.3 91.5 62.1 12.9 0.0 173.6 77.5 43.3 27.4 105.6 3.6 83.5 188.1 91.2 14.9 78.5 0.6 16.0 743.3 182.0 24.5 232.5 422.1 8.1 94.9 527.0 410.7 11.8 0.8 26.1 26.4 214.1 81.1 12.3 39.7 277.1 87.2 10.3 50.2 44.4 30.9 3.5 2.6 37.4 45.7 69.2 45.3 109.0 382.5 267.9 16.9 4.8 13.1 36.1 68.8 8.0 25.9 12.3 108.5 1815.2 123.3 21.4 44.3 263.3 PLIN4 "KIAA1881, S3-12" ENSG00000167676 "Perilipin 4" Q96Q06 19 4502180-4518465 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 764.9;breast: 316.5;skeletal muscle: 249.9" "Cell type enhanced" "Detected in some" "Adipocytes: 12.3;Astrocytes: 12.1;Cardiomyocytes: 35.9;Hepatocytes: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "ASC diff: 249.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA044682, HPA054657" Enhanced Enhanced "Lipid droplets,Plasma membrane,Cytosol" NA NA 55000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Lipid droplets" "HPA044682: AB_2679044, HPA054657: AB_2682559" "unprognostic (2.97e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (8.31e-4)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.65e-2)" "unprognostic (6.77e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-2)" "unprognostic (9.89e-3)" "unprognostic (1.05e-1)" "unprognostic (2.95e-2)" "unprognostic (1.81e-1)" "unprognostic (1.90e-1)" "unprognostic (6.09e-3)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (4.94e-3)" 764.9 3.9 8.5 6.4 9.4 2.7 316.5 8.0 5.1 8.8 2.5 70.7 2.3 28.7 2.0 9.6 18.5 8.5 112.8 5.0 6.7 7.6 87.1 3.4 0.8 9.8 9.7 21.8 24.7 0.1 4.4 0.1 7.3 13.4 3.9 0.2 22.6 15.1 249.9 16.3 18.9 20.4 8.5 4.9 25.1 2.7 11.1 0.9 4.1 163.4 0.2 34.3 7.2 7.1 0.1 0.4 0.1 0.7 249.6 1.6 8.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.4 0.0 1.2 0.1 0.0 1.8 0.0 0.6 0.3 0.0 0.1 1.4 3.6 0.1 0.1 8.1 4.7 0.0 0.4 0.1 0.0 0.0 0.2 0.5 0.0 0.5 0.0 0.2 0.3 0.1 5.7 0.3 0.0 0.2 0.0 29.7 0.1 0.4 0.3 0.0 0.0 0.1 1.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 9.4 8.0 5.1 5.0 6.7 9.8 9.7 7.3 8.5 11.1 7.1 12.3 0.0 7.2 12.1 0.2 0.3 1.2 0.4 0.6 0.3 0.9 3.9 35.9 7.2 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.3 1.6 0.4 1.0 0.0 0.0 0.3 1.5 0.3 1.7 3.6 0.6 0.0 1.0 7.5 30.6 0.1 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.6 0.0 0.5 0.0 0.6 0.0 4.1 0.0 0.4 0.0 0.9 0.9 0.0 6.6 5.9 1.8 0.5 0.4 0.3 0.3 0.4 0.1 0.3 0.3 1.9 PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55534969 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 359.1;Endometrial stromal cells: 206.7;Hepatic stellate cells: 267.0;Leydig cells: 219.3;Prostatic glandular cells: 182.0" "Cancer enhanced" "Detected in all" "prostate cancer: 200.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 445.7;fHDF/TERT166: 142.8;HMC-1: 235.8;HSkMC: 171.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB033331: AB_2168044, HPA047815: AB_2680164" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "prognostic favorable (6.06e-4)" "unprognostic (2.81e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (2.43e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.94e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-2)" 172.3 78.1 51.5 42.3 59.9 0.9 140.7 63.7 59.4 88.7 59.6 118.3 47.4 119.5 39.8 42.4 73.4 167.5 117.1 49.9 56.8 104.0 67.7 56.2 32.2 62.1 56.2 29.4 35.6 49.0 27.8 37.6 64.2 254.1 65.8 9.7 32.9 61.3 70.0 57.9 79.1 108.9 62.5 31.1 70.9 21.0 58.6 15.8 112.9 81.5 24.2 128.8 63.8 72.9 9.8 24.4 7.0 14.2 445.7 51.8 9.6 21.8 61.4 11.9 27.9 16.7 17.7 10.2 20.0 142.8 31.9 6.5 25.2 12.6 13.5 6.8 20.1 1.1 9.6 21.3 70.5 2.5 235.8 171.3 25.7 17.6 10.9 23.3 19.9 9.1 0.2 27.0 24.1 6.0 6.8 5.5 15.5 1.1 20.0 2.0 11.7 0.9 46.3 79.8 8.4 5.8 21.5 4.2 13.4 28.8 15.6 1.6 24.0 4.0 6.9 17.8 15.5 16.6 7.4 11.8 15.7 1.3 19.5 0.0 0.4 4.0 1.6 0.5 1.7 6.7 5.3 3.4 2.0 3.3 9.5 7.7 0.3 3.0 0.9 15.0 2.6 1.8 51.5 59.9 63.7 59.4 49.9 56.8 62.1 56.2 64.2 62.5 58.6 72.9 359.1 6.4 9.4 0.0 9.8 0.0 51.0 0.0 10.2 4.0 8.4 45.7 0.0 21.5 5.6 29.5 2.1 3.3 5.4 61.0 5.9 25.2 44.4 10.7 206.7 112.3 1.2 5.7 0.0 28.5 11.1 115.5 11.2 18.5 27.8 4.0 267.0 48.3 12.8 1.7 0.0 20.2 0.0 12.0 0.0 21.0 219.3 8.1 0.0 0.0 4.5 16.6 1.0 0.0 0.0 30.0 24.6 88.4 13.0 182.0 49.4 29.3 2.2 5.6 59.2 89.7 49.7 54.4 17.7 10.0 0.0 4.9 11.3 3.1 12.1 42.8 PLTP BPIFE ENSG00000100979 "Phospholipid transfer protein" P55058 20 45898621-45912155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Hofbauer cells: 1640.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 33.1;eosinophil: 29.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 220.8;BEWO: 186.8;HHSteC: 233.2;HSkMC: 302.2;U-87 MG: 326.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032873 Approved "Secreted to blood" NA NA 9720000000 210000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032873: AB_2283977" "unprognostic (1.27e-1)" "unprognostic (3.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (4.19e-2)" "unprognostic (8.30e-2)" "unprognostic (3.19e-2)" "unprognostic (2.65e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (9.52e-8)" "unprognostic (3.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (9.68e-2)" 437.9 188.9 107.9 80.5 109.8 20.7 122.6 100.8 142.0 155.4 197.6 76.9 41.6 114.9 72.6 62.0 173.5 182.3 123.4 100.4 119.0 198.9 29.5 97.1 61.3 119.5 152.2 159.5 296.9 22.1 38.5 428.8 126.0 50.7 42.4 4.8 132.1 71.5 24.0 68.0 71.6 181.9 124.7 57.6 89.7 32.3 114.5 229.9 44.4 20.8 21.1 339.7 113.1 118.1 13.8 1.9 94.9 0.1 220.8 66.8 186.8 5.3 16.3 18.5 11.0 78.7 15.9 3.5 151.6 23.6 0.4 154.7 29.2 0.6 8.4 1.8 0.2 28.8 3.3 37.7 233.2 0.0 35.5 302.2 7.7 49.1 0.9 74.1 41.3 3.2 9.5 44.9 6.2 3.9 3.2 123.1 16.9 12.5 74.5 1.3 0.1 1.7 0.5 0.0 10.1 35.4 3.7 110.3 160.9 15.7 1.5 117.2 9.0 46.2 1.1 24.2 0.8 19.7 5.3 5.4 326.4 34.3 7.8 33.1 2.7 29.7 1.6 7.1 1.2 8.7 0.4 1.6 2.5 3.2 0.0 1.0 1.4 4.9 12.6 17.5 0.8 2.7 107.9 109.8 100.8 142.0 100.4 119.0 119.5 152.2 126.0 124.7 114.5 118.1 21.9 0.0 2.3 30.3 3.8 40.7 34.9 53.0 33.0 0.4 9.5 22.6 1.5 5.7 9.6 27.6 0.0 14.8 3.5 0.5 1.9 3.4 16.3 54.6 36.9 27.9 0.0 9.0 0.8 103.2 97.7 256.8 3.6 5.7 0.0 23.4 121.1 2.8 1640.3 3.3 1.4 1.2 12.2 254.0 40.9 24.9 307.9 71.8 35.6 4.7 3.8 13.8 7.2 0.5 0.2 9.9 0.0 199.0 11.8 15.7 0.0 18.2 70.8 1.1 32.9 16.1 35.6 5.7 7.3 24.0 35.8 31.7 3.3 99.5 0.7 18.4 PNPLA2 "ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2" ENSG00000177666 "Patatin like phospholipase domain containing 2" Q96AD5 11 818914-825573 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 508.1;breast: 361.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055173, HPA062602, HPA075175" Approved Enhanced "Nucleoplasm,Lipid droplets" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "HPA055173: AB_2682725, HPA062602: AB_2684804, HPA075175: " "unprognostic (2.11e-2)" "unprognostic (3.37e-2)" "unprognostic (5.87e-3)" "unprognostic (2.51e-2)" "unprognostic (8.97e-3)" "unprognostic (1.68e-2)" "unprognostic (6.39e-2)" "unprognostic (3.28e-2)" "unprognostic (3.00e-1)" "unprognostic (5.61e-2)" "unprognostic (7.93e-2)" "unprognostic (2.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "unprognostic (5.46e-1)" "unprognostic (4.09e-1)" "unprognostic (2.07e-2)" 508.1 75.3 11.9 9.2 14.0 43.1 361.4 13.6 18.8 42.2 13.4 58.1 19.3 49.2 2.8 39.9 50.8 9.5 171.3 11.9 14.0 61.9 58.4 57.3 8.1 17.5 11.8 50.5 75.4 9.6 46.3 8.4 16.8 46.6 4.8 1.3 81.1 16.7 194.6 71.8 74.7 6.4 12.6 51.2 71.3 32.1 12.8 10.9 55.3 64.3 4.1 64.8 44.5 15.3 33.9 26.0 5.3 14.0 194.4 17.2 34.1 35.3 28.1 21.6 19.1 22.3 33.3 19.9 20.4 26.7 13.6 30.0 8.1 14.6 6.6 25.9 71.5 27.6 11.2 36.3 63.3 19.2 33.4 33.9 18.7 14.5 16.7 22.3 17.7 14.5 23.8 19.9 19.5 20.0 25.8 42.3 15.2 34.3 55.1 24.6 11.5 45.7 21.4 7.7 19.6 26.0 65.3 55.0 21.9 3.4 23.7 22.0 32.5 19.3 15.0 12.7 16.3 75.2 49.8 16.7 48.4 27.0 13.8 11.5 9.5 22.1 3.7 6.1 3.6 4.7 4.8 5.4 6.1 4.1 5.4 4.4 8.2 4.0 7.1 7.0 4.2 4.7 11.9 14.0 13.6 18.8 11.9 14.0 17.5 11.8 16.8 12.6 12.8 15.3 78.1 6.4 11.8 12.7 63.5 44.2 69.2 34.2 42.1 14.0 79.5 67.1 45.5 61.5 65.2 51.5 8.4 70.2 50.8 151.8 33.2 65.1 22.1 58.0 31.8 51.8 51.5 52.6 8.9 65.3 32.0 37.4 204.4 114.3 11.4 42.2 100.6 50.6 29.2 11.8 7.5 96.1 20.3 27.6 29.0 6.2 48.4 46.6 42.7 16.9 29.6 32.2 21.6 5.5 13.8 142.2 170.7 39.1 92.0 78.5 166.8 45.0 31.3 9.0 65.7 64.4 50.7 33.5 23.9 53.7 41.2 169.4 53.3 182.2 43.6 195.5 PODNL1 "FLJ23447, SLRR5B" ENSG00000132000 "Podocan like 1" Q6PEZ8 19 13931187-13953392 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 13.4;Bipolar cells: 38.7;Leydig cells: 18.3;Peritubular cells: 38.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 6.6;HSkMC: 11.6;hTERT-RPE1: 18.8;SiHa: 9.7;U-2 OS: 6.7" "Not detected" "Not detected" "Region enriched" "Detected in some" 11 "spinal cord: 18.9" HPA042807 Approved "Secreted - unknown location" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "HPA042807: AB_10795514" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (8.08e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.61e-8)" "unprognostic (1.78e-1)" "unprognostic (1.86e-2)" "unprognostic (3.68e-1)" "unprognostic (2.02e-1)" "unprognostic (3.08e-3)" "unprognostic (4.37e-2)" "unprognostic (1.01e-1)" "unprognostic (0.00e+0)" "unprognostic (3.94e-3)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (4.49e-4)" 1.8 0.7 1.9 0.9 1.7 0.5 4.9 2.3 1.8 5.6 0.8 2.8 0.4 1.5 0.2 8.2 2.1 1.3 4.7 1.2 3.6 1.7 0.5 5.1 0.2 4.3 4.4 3.3 1.5 0.1 5.1 3.7 3.0 7.9 0.3 2.0 5.3 0.9 1.6 11.4 2.3 0.5 3.1 1.0 1.7 7.2 3.7 0.0 3.1 1.3 0.2 2.7 12.0 2.0 0.3 0.4 0.4 0.2 0.6 1.5 0.1 4.1 2.4 0.8 1.6 0.3 0.4 0.2 0.3 6.6 0.2 1.6 0.1 0.1 0.4 1.5 0.6 0.8 0.4 0.0 5.1 0.2 0.5 11.6 0.7 1.1 0.1 18.8 0.0 0.1 0.4 0.3 1.6 2.7 0.2 0.2 0.1 0.3 0.4 0.1 0.1 0.0 0.3 0.0 0.7 0.4 9.7 0.1 0.3 0.4 0.1 0.5 0.7 2.0 6.7 0.5 0.2 0.3 0.0 0.1 0.8 0.9 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.9 1.7 2.3 1.8 1.2 3.6 4.3 4.4 3.0 3.1 3.7 2.0 1.4 0.0 0.5 2.3 0.0 1.3 0.9 13.4 0.0 38.7 2.1 8.0 1.6 0.0 1.4 0.0 2.1 0.4 0.2 1.8 0.0 0.2 1.7 0.5 6.1 0.9 0.0 2.7 0.5 0.0 0.2 4.7 0.0 0.4 0.0 0.5 0.7 0.1 9.8 1.7 0.7 1.1 0.0 1.2 1.7 2.1 18.3 0.9 1.8 1.9 0.0 1.8 0.0 1.5 0.3 0.6 9.0 38.0 0.0 0.5 0.6 0.1 1.4 4.6 0.0 0.6 1.0 1.0 0.7 2.6 4.3 0.8 0.2 0.1 1.4 1.6 POLN ENSG00000130997 "DNA polymerase nu" Q7Z5Q5 4 2071918-2242121 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 2.4;testis: 2.6" "Cell type enhanced" "Detected in many" "Astrocytes: 32.3;Excitatory neurons: 77.7;Inhibitory neurons: 42.7;Oligodendrocyte precursor cells: 22.1;Oligodendrocytes: 26.8;Spermatocytes: 23.4" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "ASC diff: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035939, HPA035940" Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA035939: AB_2674875, HPA035940: AB_2674876" "unprognostic (8.52e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-2)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (1.45e-2)" "unprognostic (3.46e-1)" "unprognostic (2.70e-1)" "unprognostic (5.83e-2)" "unprognostic (2.23e-1)" "unprognostic (2.02e-3)" "unprognostic (1.25e-1)" "unprognostic (1.49e-3)" "unprognostic (9.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" 2.4 0.6 0.3 0.0 0.4 0.0 1.0 0.2 0.5 0.3 0.0 0.3 0.1 0.3 0.7 0.1 0.4 0.3 0.3 0.3 0.0 0.4 0.4 0.2 0.2 0.0 0.0 0.2 0.4 0.1 0.4 0.1 0.0 0.6 0.0 0.2 0.5 0.2 0.4 0.3 0.3 0.1 0.0 0.3 0.3 2.6 0.1 0.1 0.3 0.1 0.1 0.2 0.2 0.4 0.0 0.6 0.0 0.3 1.7 0.5 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.2 0.7 0.2 0.3 0.2 0.5 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 2.4 0.0 0.0 32.3 1.0 0.9 1.0 0.6 0.6 4.2 3.0 1.5 3.6 1.5 1.7 0.0 0.0 0.2 0.6 0.2 3.9 0.4 8.3 4.2 2.0 1.9 4.8 0.8 77.7 1.0 0.3 2.0 1.5 2.1 0.0 5.5 3.3 1.1 0.7 3.3 42.7 0.0 2.0 1.3 1.0 14.1 4.4 1.3 0.0 15.0 0.7 2.5 1.0 22.1 26.8 0.5 1.1 3.8 1.5 1.0 0.3 0.8 1.9 3.8 0.0 2.9 1.1 23.4 10.4 0.5 1.6 0.0 1.8 4.1 0.3 1.3 POR "CYPOR, FLJ26468" ENSG00000127948 "Cytochrome p450 oxidoreductase" P16435 7 75899200-75986855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Congenital adrenal hyperplasia, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 313.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 489.2;Proximal enterocytes: 274.2;Theca cells: 647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 328.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004372, HPA010136" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 12000 "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" Cytosol "CAB004372: AB_627391, HPA010136: AB_1079657" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (9.89e-2)" 53.4 197.4 19.9 32.1 20.7 17.9 44.7 14.1 18.6 42.0 15.5 35.9 105.2 32.1 29.4 53.6 50.2 37.0 43.3 20.7 30.2 38.1 313.3 55.0 19.9 22.2 24.5 52.2 44.5 77.6 71.4 46.3 20.9 31.8 21.9 12.7 29.9 113.1 56.2 43.8 92.4 28.2 16.9 43.8 41.5 25.5 34.7 38.0 131.3 68.1 23.2 36.6 42.3 15.3 59.6 133.0 57.0 106.3 212.9 79.8 98.0 24.4 79.3 44.7 62.3 100.7 257.0 56.1 21.9 53.1 151.8 28.3 76.0 38.4 19.6 48.1 57.9 26.0 36.9 189.4 146.5 26.2 45.5 163.9 47.4 59.2 43.2 36.3 42.3 27.1 79.1 24.0 40.8 90.9 29.0 49.4 71.7 92.9 74.8 41.0 37.6 61.1 50.0 72.8 59.3 57.4 65.4 328.4 91.0 32.6 94.0 44.2 38.6 41.7 45.8 63.6 48.7 23.8 38.3 39.0 59.3 39.8 54.9 65.9 42.6 60.4 20.6 39.6 17.1 11.0 17.5 19.4 45.6 11.2 17.1 14.7 53.8 25.9 30.2 12.5 19.3 36.6 19.9 20.7 14.1 18.6 20.7 30.2 22.2 24.5 20.9 16.9 34.7 15.3 34.3 38.5 39.7 23.2 17.1 17.1 29.4 172.3 13.1 31.4 20.5 14.0 10.9 54.3 201.4 73.5 12.5 99.9 26.0 97.7 1.9 65.0 27.6 62.1 28.0 27.1 19.8 11.8 10.1 29.4 95.0 40.1 67.8 46.6 24.7 121.4 32.2 489.2 67.8 15.2 17.1 41.7 124.1 35.2 16.1 9.5 75.8 47.3 12.4 11.2 20.5 25.9 12.3 11.6 8.8 27.9 102.0 112.5 17.0 20.7 274.2 31.7 178.6 23.0 65.7 32.7 46.9 21.3 30.8 18.2 14.6 193.2 25.4 647.6 44.5 45.9 PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036725 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 251.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 229.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" NA NA 3700000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA039163: AB_2676374" "unprognostic (7.81e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.49e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (3.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" "unprognostic (4.27e-2)" "unprognostic (2.43e-2)" 37.0 20.6 5.3 16.4 5.6 0.2 30.4 6.8 7.0 42.3 12.2 41.4 37.3 31.0 36.5 46.8 14.8 33.5 44.4 5.2 5.8 24.9 28.9 27.0 7.6 6.4 6.3 16.2 30.3 20.9 6.2 48.3 6.2 23.4 49.9 4.9 31.7 24.0 41.2 20.2 32.3 45.2 6.1 7.7 22.4 9.0 6.7 5.8 47.2 33.3 14.2 45.8 28.8 5.8 19.6 16.8 6.4 136.2 229.7 104.6 26.9 54.4 42.3 27.8 56.7 28.1 128.6 0.0 94.2 147.1 83.3 21.9 18.9 68.6 22.1 0.1 33.1 27.8 60.7 32.8 58.9 0.0 14.7 65.8 51.5 32.5 34.0 49.9 58.1 0.0 7.9 0.0 20.1 116.5 0.1 0.3 11.6 120.9 29.0 0.0 14.5 0.0 87.7 67.0 8.5 14.9 106.7 51.1 12.1 77.8 72.0 61.8 64.8 52.9 32.7 18.5 23.9 0.2 0.1 0.4 45.9 0.2 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.6 6.8 7.0 5.2 5.8 6.4 6.3 6.2 6.1 6.7 5.8 214.1 32.1 16.5 6.2 1.6 47.4 52.3 251.7 30.7 16.9 63.9 47.5 46.4 61.5 149.0 73.5 4.2 60.1 0.6 134.0 29.4 201.5 1.7 52.4 94.8 106.5 12.7 0.0 0.8 126.4 65.2 198.2 55.0 50.8 1.3 54.2 80.7 57.8 43.2 0.0 2.2 177.1 207.5 4.2 40.3 4.2 112.5 6.9 32.0 5.6 3.2 2.8 0.0 1.0 0.3 90.3 181.0 100.1 0.6 48.2 189.0 81.7 110.5 4.4 39.5 22.7 87.5 41.6 37.8 118.6 49.3 25.0 3.4 61.2 117.0 81.5 PPIL6 "bA425D10.6, dJ919F19.1, MGC41939, RSPH12" ENSG00000185250 "Peptidylprolyl isomerase like 6" Q8IXY8 6 109390215-109441171 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 35.6;testis: 18.9" "Cell type enhanced" "Detected in many" "Early spermatids: 374.4;Endometrial ciliated cells: 226.5;Late spermatids: 75.1;Respiratory ciliated cells: 228.6;Spermatocytes: 101.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AN3-CA: 6.0;ASC diff: 9.2;ASC TERT1: 11.5;hTERT-RPE1: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036717, HPA058165" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA036717: AB_10671969, HPA058165: " "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (5.68e-2)" "unprognostic (2.68e-2)" "unprognostic (3.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-1)" "unprognostic (5.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.03e-2)" "unprognostic (1.42e-3)" "unprognostic (2.51e-2)" "unprognostic (4.71e-2)" "unprognostic (1.95e-1)" "unprognostic (3.29e-2)" "unprognostic (5.86e-2)" "unprognostic (2.32e-1)" 1.1 0.9 4.7 0.6 5.2 0.2 3.0 5.7 5.3 3.8 12.2 1.3 1.4 3.0 9.0 1.4 35.6 1.1 2.1 4.8 5.2 4.3 0.6 4.7 0.6 7.5 8.2 5.3 2.3 5.2 2.7 1.1 5.5 1.2 1.0 7.4 2.3 2.7 4.3 1.3 0.7 2.0 7.2 0.8 1.7 18.9 5.1 0.8 11.1 1.7 0.6 1.5 1.2 7.6 1.4 1.2 1.1 6.0 9.2 11.5 0.6 0.0 2.2 0.5 0.1 0.1 1.6 0.0 0.4 0.6 0.8 0.9 1.0 0.0 0.3 0.4 0.4 0.5 0.1 0.0 4.6 0.5 0.2 2.4 5.6 0.2 3.5 8.6 0.7 1.3 0.6 0.4 0.4 0.6 0.1 0.7 0.2 4.0 0.8 0.6 0.0 0.5 4.7 0.1 1.3 2.1 0.1 0.3 3.9 0.3 0.4 0.9 0.3 0.1 0.2 1.0 0.2 0.2 0.1 0.1 1.9 0.1 0.4 0.8 0.1 0.2 0.1 0.1 0.1 1.5 0.2 0.1 0.3 0.5 0.1 0.1 0.4 0.4 0.1 0.4 0.1 0.2 4.7 5.2 5.7 5.3 4.8 5.2 7.5 8.2 5.5 7.2 5.1 7.6 2.6 6.4 6.9 11.8 1.8 2.2 3.7 18.2 2.8 2.4 5.7 7.0 3.7 2.8 22.1 3.7 2.1 0.8 0.4 0.9 25.4 1.9 374.4 226.5 7.3 1.8 3.0 0.4 15.0 1.2 0.8 3.9 2.6 5.8 0.0 4.1 1.1 0.2 0.4 1.7 6.1 2.0 22.4 0.0 0.3 75.1 5.3 1.1 3.6 3.7 0.6 7.8 0.0 8.5 6.2 0.7 0.8 5.3 0.8 3.8 1.5 13.0 228.6 13.4 0.0 5.2 5.6 101.4 21.5 1.9 3.0 0.7 1.2 3.0 2.0 1.5 PPM1M "FLJ32332, PP2Ceta" ENSG00000164088 "Protein phosphatase, Mg2+/Mn2+ dependent 1M" Q96MI6 3 52245759-52250599 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 42.2;Kupffer cells: 39.0;Macrophages: 31.1;NK-cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 54.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036905, HPA062291" Uncertain Approved "Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear bodies" "HPA036905: AB_10602818, HPA062291: AB_2684740" "unprognostic (4.26e-3)" "prognostic favorable (7.73e-4)" "unprognostic (2.55e-2)" "unprognostic (4.85e-3)" "unprognostic (5.64e-2)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "prognostic favorable (6.69e-4)" "unprognostic (4.63e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.49e-1)" "unprognostic (4.14e-2)" "unprognostic (9.27e-2)" "unprognostic (4.37e-2)" 19.5 9.4 12.7 20.3 13.7 24.6 15.5 9.9 13.6 25.9 12.2 18.7 6.0 18.3 9.9 12.3 18.1 14.1 11.4 13.6 14.2 10.9 5.6 23.5 29.6 12.8 11.4 18.6 8.0 11.2 9.1 11.6 12.2 16.7 8.7 2.2 11.6 15.2 3.7 10.7 13.1 18.0 12.0 30.1 11.4 8.8 15.5 27.6 13.8 7.8 28.2 17.5 18.2 12.9 0.9 5.4 3.2 7.6 46.1 45.7 5.2 12.2 26.2 17.0 13.1 3.2 4.2 9.0 3.6 32.0 9.5 1.5 10.9 2.3 6.9 11.0 2.7 20.5 14.6 3.3 33.6 3.1 18.7 37.8 5.2 18.9 11.9 27.3 22.2 40.5 3.6 14.5 20.2 2.2 13.7 0.9 4.1 4.0 14.7 3.0 1.6 20.0 7.3 2.6 2.3 9.3 9.0 2.2 11.1 6.8 7.6 7.9 15.5 6.5 10.7 3.8 1.6 54.3 11.2 9.9 12.7 5.4 8.0 1.8 24.1 13.3 20.6 19.3 15.9 6.8 16.1 19.2 14.4 7.4 15.2 19.0 28.9 11.7 29.6 8.5 20.5 17.5 12.7 13.7 9.9 13.6 13.6 14.2 12.8 11.4 12.2 12.0 15.5 12.9 6.8 0.0 5.4 1.3 15.4 5.1 6.5 0.7 8.0 1.6 5.9 7.2 1.8 5.7 2.0 1.8 0.0 3.3 25.9 0.7 3.9 1.8 9.7 4.7 8.9 7.0 1.2 3.0 1.5 1.1 5.8 11.9 3.1 11.0 5.7 7.3 12.5 3.7 42.2 1.7 0.6 0.4 2.0 39.0 17.0 18.0 12.8 31.1 5.4 4.7 29.1 5.1 30.9 1.5 0.7 1.3 3.2 9.8 11.4 2.3 0.9 3.0 0.9 0.7 19.7 5.2 7.3 0.7 4.2 11.9 3.8 1.9 25.1 3.1 1.0 3.5 PRAF2 "JM4, Yip6a" ENSG00000243279 "PRA1 domain family member 2" O60831 X 49071161-49074002 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 163.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002859, HPA005504, CAB011655" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "CAB011655: , HPA002859: AB_1079672, HPA005504: AB_2667340" "unprognostic (1.50e-1)" "prognostic favorable (7.42e-4)" "unprognostic (1.17e-2)" "unprognostic (1.32e-2)" "unprognostic (4.29e-1)" "unprognostic (3.67e-1)" "prognostic unfavorable (1.66e-6)" "prognostic favorable (2.81e-4)" "unprognostic (6.10e-2)" "unprognostic (3.77e-1)" "prognostic favorable (4.88e-6)" "unprognostic (8.39e-3)" "prognostic unfavorable (5.83e-6)" "unprognostic (4.96e-2)" "unprognostic (1.69e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" 26.5 38.7 66.9 15.6 67.3 8.2 23.2 67.2 82.5 43.2 63.8 32.3 6.1 51.5 163.4 11.7 36.0 14.8 32.0 66.7 72.1 26.3 11.5 29.7 12.8 69.4 73.8 37.7 10.5 29.2 74.5 11.4 73.9 26.4 11.1 21.6 13.9 35.8 12.1 14.7 17.8 43.6 66.1 21.7 21.9 28.2 71.1 21.5 27.7 9.0 14.9 33.1 26.0 69.8 17.0 35.0 40.0 51.5 140.4 84.7 5.0 59.1 61.9 39.7 43.2 2.0 5.3 1.7 14.0 129.3 32.6 15.5 1.6 32.3 43.6 31.3 45.4 13.4 43.0 1.8 143.2 8.8 25.0 108.3 27.0 75.0 54.0 80.9 61.6 41.3 2.1 4.6 69.5 31.4 56.6 10.6 22.5 8.3 2.3 30.8 21.9 3.8 60.0 5.0 26.6 66.3 49.5 25.5 35.2 35.1 25.0 6.2 37.8 30.1 39.6 65.6 17.5 71.7 19.8 13.4 72.7 15.3 48.1 47.0 13.0 18.5 38.6 15.0 43.2 32.0 41.6 33.9 14.9 30.2 36.7 40.1 34.1 39.0 11.2 5.9 68.4 26.0 66.9 67.3 67.2 82.5 66.7 72.1 69.4 73.8 73.9 66.1 71.1 69.8 21.5 12.8 10.0 7.5 8.7 7.6 14.9 34.8 11.4 23.1 8.0 10.7 5.8 11.5 16.3 11.0 12.5 3.3 13.2 2.2 11.7 16.7 3.4 6.8 31.6 30.9 10.2 5.2 5.8 5.7 13.4 29.9 4.1 9.2 15.9 13.4 33.5 3.6 6.1 16.8 7.0 4.7 40.7 5.7 11.3 6.0 38.2 6.6 14.2 5.6 5.6 29.2 16.5 3.5 9.9 4.1 0.8 41.3 10.5 10.1 1.5 18.5 17.7 8.6 19.7 13.2 33.4 14.7 4.5 5.0 7.4 9.7 17.5 36.3 1.5 9.3 PRCP "HUMPCP, PCP" ENSG00000137509 Prolylcarboxypeptidase P42785 11 82822936-82970584 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 348.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 463.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017065, HPA071115" Approved Supported Vesicles "Intracellular and membrane" NA NA 42000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA017065: AB_1855676, HPA071115: " "unprognostic (3.24e-1)" "unprognostic (2.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" "unprognostic (1.33e-2)" "unprognostic (9.22e-2)" "unprognostic (1.42e-1)" "unprognostic (7.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.70e-1)" "unprognostic (1.88e-2)" "prognostic favorable (2.65e-6)" "unprognostic (7.16e-2)" "unprognostic (1.73e-2)" "unprognostic (3.49e-1)" "unprognostic (4.07e-1)" 74.8 87.3 81.1 57.8 82.1 37.7 70.0 84.3 109.1 91.9 95.0 49.3 28.6 62.9 81.4 62.1 57.0 64.3 70.0 76.6 85.6 144.7 151.9 58.1 92.1 84.4 82.1 53.5 37.9 78.4 34.5 152.8 80.9 52.5 46.6 21.9 85.6 55.5 15.9 54.1 31.8 80.8 89.0 54.0 32.0 41.8 86.0 33.7 63.7 28.5 85.0 100.2 57.5 86.7 34.9 41.8 49.6 121.0 463.5 146.7 67.1 67.5 131.9 70.9 97.0 103.5 70.7 55.9 100.7 117.9 72.6 53.2 53.7 45.2 72.0 43.9 38.3 37.7 56.5 76.7 86.2 31.0 124.7 122.0 39.3 72.7 68.6 166.5 224.0 26.3 39.1 69.8 72.7 19.5 4.9 171.7 33.9 90.3 31.1 27.1 97.0 65.1 118.0 71.2 24.0 51.9 101.9 60.2 41.5 80.6 66.6 49.6 65.0 78.8 77.4 71.1 33.5 64.2 113.6 46.3 32.9 41.7 44.5 53.5 76.9 50.9 13.7 79.0 16.1 31.7 14.0 15.9 140.2 34.2 12.0 17.4 89.0 34.7 64.8 27.9 14.8 49.6 81.1 82.1 84.3 109.1 76.6 85.6 84.4 82.1 80.9 89.0 86.0 86.7 86.9 19.2 12.9 58.8 45.5 31.4 41.5 53.4 25.0 11.7 26.2 25.1 26.6 37.1 25.2 62.5 2.1 65.1 29.0 9.8 29.4 32.9 44.9 17.4 37.7 180.4 19.7 13.7 42.2 12.0 120.1 73.6 23.9 29.9 12.7 18.2 348.7 65.4 80.7 16.8 38.5 19.1 14.2 152.9 118.9 47.6 44.1 88.0 71.2 33.7 79.5 53.5 28.8 34.7 10.5 8.2 10.2 46.3 62.2 23.3 3.9 83.8 9.1 5.3 65.7 25.5 25.6 60.8 6.3 54.3 34.9 52.9 22.3 27.7 20.9 39.2 PRDX6 "1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX" ENSG00000117592 "Peroxiredoxin 6" P30041 1 173477330-173488815 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1315.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006983, CAB008663" Supported Supported "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB008663: AB_1620994, HPA006983: AB_1079595" "unprognostic (9.92e-2)" "unprognostic (1.50e-1)" "unprognostic (3.67e-1)" "unprognostic (2.99e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (5.71e-3)" "unprognostic (2.80e-2)" "unprognostic (5.27e-3)" "unprognostic (3.96e-3)" "unprognostic (3.19e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.51e-4)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (1.15e-1)" "unprognostic (4.73e-3)" 340.7 157.5 169.5 68.3 181.3 100.1 211.2 197.6 210.1 112.3 164.8 189.1 46.4 108.8 206.3 127.9 149.8 71.9 261.8 184.1 196.6 184.4 482.5 116.7 72.2 181.0 198.3 115.5 114.4 217.5 67.4 70.7 187.5 152.1 221.6 53.9 85.6 99.0 563.5 106.6 59.8 160.2 175.8 70.7 135.2 119.1 176.7 70.7 106.0 382.4 79.0 99.5 109.8 185.5 420.3 127.7 204.7 230.9 778.5 372.7 169.5 843.9 284.3 342.7 241.8 243.9 276.4 272.4 256.4 694.2 120.4 239.8 272.0 259.9 279.0 234.0 243.6 179.5 200.0 277.7 425.7 191.3 56.1 301.0 262.6 181.3 256.6 210.8 339.5 106.7 405.4 52.8 392.9 86.3 131.7 249.1 456.2 219.8 760.5 154.5 236.6 277.0 518.1 95.4 94.9 173.4 285.0 334.0 199.2 296.3 283.8 262.9 228.2 132.5 149.9 201.8 229.5 76.4 123.2 220.7 159.4 162.3 124.3 36.2 42.5 24.8 29.8 39.8 32.8 32.6 29.8 38.4 53.5 24.4 39.8 47.9 25.2 25.7 36.5 79.7 36.1 58.1 169.5 181.3 197.6 210.1 184.1 196.6 181.0 198.3 187.5 175.8 176.7 185.5 278.1 176.3 170.8 127.3 127.4 235.4 404.1 382.8 209.5 31.9 186.1 250.7 528.6 301.7 228.6 277.7 29.2 714.3 158.6 1315.9 860.8 178.6 237.5 206.9 226.8 191.8 142.1 449.5 13.8 202.3 939.1 307.0 111.6 200.0 348.6 216.6 214.2 1120.2 345.0 45.4 13.2 257.4 205.4 164.3 161.0 667.5 340.5 227.1 183.2 17.8 212.9 462.5 83.4 12.5 15.4 147.2 663.4 416.8 176.4 427.1 264.4 827.3 209.1 52.0 184.1 185.7 253.8 123.5 76.8 305.9 264.1 963.5 157.7 512.5 303.6 308.9 PRELP "prolargin, SLRR2A" ENSG00000188783 "Proline and arginine rich end leucine rich repeat protein" P51888 1 203475806-203491352 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 206.6;Leydig cells: 100.6;Melanocytes: 192.1;Muller glia cells: 152.4;Peritubular cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.1" "Group enriched" "Detected in some" 5 "ASC diff: 18.0;BJ: 7.7;fHDF/TERT166: 11.7;SuSa: 5.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 82.4" HPA059225 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA059225: " "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.83e-2)" "unprognostic (6.56e-2)" "unprognostic (2.75e-2)" "unprognostic (1.61e-1)" "unprognostic (2.84e-2)" "unprognostic (3.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (5.62e-6)" "unprognostic (2.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.02e-4)" 114.8 23.4 12.6 4.2 14.2 0.5 77.5 7.7 20.2 126.7 20.0 136.4 6.6 147.7 7.6 41.3 108.6 40.4 212.0 11.6 10.0 25.3 15.6 124.7 8.0 10.2 8.2 128.2 13.1 2.5 22.6 12.0 9.4 73.6 8.9 21.5 32.7 77.1 35.6 56.4 61.0 51.4 8.3 44.2 41.3 7.2 10.3 3.2 60.4 36.9 15.9 147.8 92.9 9.4 0.2 0.2 0.5 0.1 18.0 0.5 0.4 7.7 1.0 0.2 0.2 0.0 0.1 1.2 0.6 11.7 0.1 0.6 0.2 0.3 0.3 0.0 0.1 0.2 0.5 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.2 2.1 0.0 0.4 0.2 0.4 1.3 0.1 0.1 0.5 0.4 0.3 0.1 0.4 0.2 0.4 0.0 0.3 1.0 0.2 0.2 0.2 0.8 5.2 0.2 0.1 0.6 0.5 0.2 0.3 0.1 0.2 0.3 1.2 0.1 0.2 0.5 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 12.6 14.2 7.7 20.2 11.6 10.0 10.2 8.2 9.4 8.3 10.3 9.4 8.8 0.0 5.8 5.2 0.9 18.2 1.0 0.0 2.2 3.6 4.2 5.1 7.4 1.5 0.6 0.0 2.1 0.1 0.3 0.1 0.0 0.0 1.1 0.6 1.7 15.6 0.0 2.7 1.6 0.0 0.1 206.6 4.6 1.6 5.1 0.2 22.9 0.3 0.3 1.7 0.2 0.0 0.0 0.3 19.2 5.3 100.6 0.9 192.1 22.5 0.0 152.4 0.0 7.5 0.5 0.0 0.0 199.7 0.4 0.6 0.0 0.1 1.5 8.9 26.3 9.6 38.3 3.1 2.4 1.6 9.9 0.3 1.6 0.1 0.0 1.3 PRG4 "bG174L6.2, CACP, FLJ32635, HAPO, JCAP, MSF, SZP" ENSG00000116690 "Proteoglycan 4" Q92954 1 186296279-186314567 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 93.2;liver: 185.7" "Group enriched" "Detected in some" 15 "Fibroblasts: 320.6;Hepatocytes: 364.7" "Cancer enriched" "Detected in many" 10 "liver cancer: 28.4" "Region enriched" "Detected in single" 33 "hypothalamus: 30.8" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.2" "Lineage enriched" "Detected in single" 12 "T-cells: 1.2" "Cell line enriched" "Detected in some" 6 "ASC diff: 284.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" CAB054258 Supported "Secreted to extracellular matrix" NA NA 4300000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB054258: " "unprognostic (8.67e-2)" "unprognostic (2.28e-1)" "unprognostic (1.82e-3)" "unprognostic (1.98e-1)" "unprognostic (1.77e-1)" "unprognostic (7.87e-2)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (1.28e-1)" "unprognostic (1.53e-1)" "unprognostic (5.03e-2)" "unprognostic (4.11e-1)" "unprognostic (1.91e-13)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (1.60e-3)" "unprognostic (7.05e-3)" 93.2 2.3 0.0 2.3 0.0 0.3 15.1 0.4 0.9 0.6 3.9 1.2 0.0 0.6 0.9 0.3 20.0 0.4 31.7 0.0 30.8 0.2 185.7 26.4 0.4 0.0 0.0 2.1 1.5 0.0 2.1 0.0 0.1 0.6 0.1 0.1 3.9 0.1 9.5 7.7 0.4 0.3 0.2 0.7 1.4 0.2 0.2 0.3 1.7 8.1 0.3 2.6 0.5 0.0 0.0 0.1 0.0 0.0 284.6 11.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 1.1 0.1 0.2 0.2 0.0 26.2 0.0 44.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.7 1.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.9 0.0 30.8 0.0 0.0 0.1 0.2 0.2 0.0 5.1 22.4 16.2 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 2.7 10.0 21.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.2 3.7 4.1 0.0 2.7 0.0 0.0 0.0 320.6 0.0 0.8 16.4 0.0 6.4 364.7 0.1 0.0 0.1 0.0 0.0 9.4 1.9 0.8 0.0 2.8 1.8 0.0 0.1 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.1 0.1 0.0 0.0 10.9 0.0 0.0 3.5 1.5 0.0 0.3 0.0 1.1 0.0 2.3 0.1 0.0 0.1 PRICKLE2 DKFZp686D143 ENSG00000163637 "Prickle planar cell polarity protein 2" Q7Z3G6 3 64092236-64445476 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 114.3;Excitatory neurons: 185.5;Inhibitory neurons: 232.4;Microglial cells: 112.4;Oligodendrocyte precursor cells: 103.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.1;ASC TERT1: 14.9;HSkMC: 22.1;U-87 MG: 15.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035493 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Vesicles "HPA035493: AB_10696504" "unprognostic (2.87e-1)" "unprognostic (4.31e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-1)" "unprognostic (3.40e-1)" "unprognostic (3.53e-3)" "unprognostic (2.92e-2)" "unprognostic (1.56e-2)" "unprognostic (1.92e-1)" "unprognostic (3.83e-2)" "unprognostic (3.03e-2)" "unprognostic (6.35e-2)" "unprognostic (1.32e-3)" "unprognostic (1.10e-2)" "unprognostic (1.91e-1)" "unprognostic (9.04e-3)" "unprognostic (1.77e-1)" 20.8 3.0 14.1 3.9 14.9 0.3 8.0 3.4 15.8 16.4 9.1 18.4 2.3 17.3 6.8 7.7 11.7 8.8 5.6 28.5 10.0 3.8 3.1 10.6 0.8 4.4 8.9 8.4 3.8 5.4 5.6 5.6 6.2 7.3 4.6 10.1 4.9 13.8 1.9 4.3 5.9 16.6 6.3 1.4 8.1 1.7 11.7 1.0 6.9 3.9 1.0 12.4 8.8 9.3 0.0 4.7 1.3 0.1 24.1 14.9 0.0 3.5 4.5 2.8 4.2 8.3 0.1 0.0 0.5 3.4 7.6 0.1 0.0 3.2 2.8 3.3 0.1 0.0 0.5 0.1 6.7 0.0 0.0 22.1 4.0 8.2 3.5 8.4 1.7 0.0 0.0 1.8 3.9 4.6 0.0 0.1 3.0 0.0 0.1 0.0 0.2 0.1 4.5 11.7 1.2 0.2 0.0 0.9 0.1 7.7 1.6 0.1 0.1 11.9 5.4 2.9 6.9 3.7 0.0 0.7 15.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 14.1 14.9 3.4 15.8 28.5 10.0 4.4 8.9 6.2 6.3 11.7 9.3 12.4 0.0 10.9 114.3 1.5 6.2 4.1 7.3 7.4 25.6 4.3 8.4 6.2 1.5 7.3 3.7 64.6 1.4 0.3 1.6 0.0 2.7 15.1 24.7 47.5 9.5 0.0 0.0 185.5 0.4 0.4 20.3 0.0 8.7 0.0 5.2 33.5 1.7 4.1 16.8 232.4 0.6 4.1 1.2 1.8 3.5 9.9 0.6 5.4 112.4 0.0 7.5 1.0 103.5 26.4 0.7 0.3 23.0 0.2 0.9 0.0 6.2 7.6 4.4 13.1 14.6 14.3 2.0 1.0 6.2 3.0 4.9 0.6 6.6 1.1 2.7 PRKAG3 ENSG00000115592 "Protein kinase AMP-activated non-catalytic subunit gamma 3" Q9UGI9 2 218822383-218832086 "FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "skeletal muscle: 70.4;tongue: 17.9" "Cell type enhanced" "Detected in single" "Skeletal myocytes: 3.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (3.51e-1)" "unprognostic (4.41e-3)" "unprognostic (2.05e-1)" "unprognostic (1.53e-1)" "unprognostic (2.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.86e-3)" "unprognostic (7.74e-2)" "unprognostic (3.44e-2)" "unprognostic (5.85e-2)" "unprognostic (3.27e-1)" "unprognostic (9.04e-2)" "unprognostic (9.95e-2)" "unprognostic (1.49e-1)" "unprognostic (2.97e-1)" "unprognostic (7.69e-2)" 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.8 0.0 70.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 17.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PRKCSH "G19P1, GIIB, PCLD, PLD1, VASAP-60" ENSG00000130175 "Protein kinase C substrate 80K-H" P14314 19 11435284-11450968 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004465, HPA041940, HPA043560" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 55000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 50: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum" "CAB004465: AB_626622, HPA041940: AB_2677758, HPA043560: AB_2678553" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (2.45e-2)" "unprognostic (2.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.63e-2)" "unprognostic (2.52e-2)" "unprognostic (5.52e-2)" "unprognostic (1.16e-1)" "unprognostic (2.07e-3)" "unprognostic (1.28e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (7.69e-4)" "unprognostic (1.63e-3)" "unprognostic (2.10e-1)" "unprognostic (3.44e-1)" "unprognostic (1.18e-1)" 115.3 107.6 76.4 81.2 86.7 169.6 117.6 85.1 97.6 144.0 91.4 119.7 120.0 123.0 113.0 106.5 126.2 92.0 90.4 76.4 82.0 108.8 159.9 105.5 93.3 89.9 83.9 196.9 186.2 116.3 118.3 108.8 85.9 108.5 98.9 46.6 145.9 97.8 74.8 129.3 121.7 78.5 79.6 111.2 124.9 88.5 83.3 83.9 135.5 44.9 86.2 109.9 122.6 88.8 274.8 216.7 211.6 391.5 351.2 426.4 241.5 305.5 387.6 331.5 302.7 328.3 327.5 204.4 478.1 409.2 165.4 283.4 226.3 309.6 292.1 193.3 173.5 178.0 269.4 268.8 258.0 263.0 236.4 404.5 228.6 312.5 261.4 425.6 232.8 210.1 204.8 422.4 289.0 470.1 187.9 322.1 485.0 129.7 283.3 201.8 215.3 505.6 223.2 260.1 146.9 291.5 282.3 280.4 280.5 200.8 292.5 296.7 263.6 437.1 198.2 416.0 361.0 471.9 575.3 132.3 330.1 276.8 306.5 38.8 47.2 45.1 37.9 36.2 42.6 35.9 31.8 36.4 36.1 38.7 30.2 33.1 56.3 32.8 41.2 75.7 37.5 39.5 76.4 86.7 85.1 97.6 76.4 82.0 89.9 83.9 85.9 79.6 83.3 88.8 45.2 12.8 16.9 15.3 65.1 41.8 72.2 90.0 39.9 18.2 56.9 47.5 10.5 71.4 44.9 64.4 33.3 174.9 54.6 152.0 33.2 88.7 18.1 47.4 65.0 52.0 58.8 40.6 12.3 127.5 189.1 62.6 70.3 67.2 41.9 104.5 60.3 86.4 93.4 10.1 12.5 123.2 65.1 80.0 43.4 55.9 78.6 59.3 53.4 14.0 81.4 59.8 61.8 6.0 39.0 89.0 132.8 72.6 91.4 45.9 187.8 62.7 32.7 30.2 39.5 39.8 52.0 36.8 55.2 49.5 37.8 143.5 55.5 84.2 128.2 66.6 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 362.1;Excitatory neurons: 147.4;Inhibitory neurons: 171.1;Microglial cells: 89.0;Oligodendrocyte precursor cells: 390.6" "Cancer enhanced" "Detected in all" "prostate cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 21.6;fHDF/TERT166: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favorable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.89e-1)" 8.0 9.6 5.6 2.2 8.0 0.0 7.7 6.5 6.7 6.4 3.7 9.5 1.0 7.9 3.5 2.1 6.5 4.4 6.1 7.5 7.5 17.5 1.6 7.5 0.3 8.6 8.6 11.2 5.4 10.6 5.6 1.9 8.7 14.7 1.3 4.7 2.9 9.3 1.6 2.8 3.6 6.3 8.9 2.3 4.6 11.7 8.1 2.4 5.9 2.6 0.5 13.1 4.6 10.3 0.0 4.4 4.8 3.1 21.6 16.5 0.1 14.1 10.4 16.7 7.3 0.0 0.3 0.0 1.9 19.4 4.0 0.1 7.9 2.1 6.8 0.0 6.2 0.0 0.0 0.5 8.8 0.0 0.1 18.4 0.3 1.4 1.5 6.1 2.6 0.0 1.4 0.4 17.4 1.8 0.0 0.0 2.6 0.0 9.6 0.0 6.3 5.2 9.7 6.6 4.3 13.0 2.6 0.0 4.5 4.6 0.0 0.1 5.6 13.6 6.7 1.0 3.7 0.0 0.0 0.0 3.5 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.0 6.5 6.7 7.5 7.5 8.6 8.6 8.7 8.9 8.1 10.3 4.6 0.0 7.4 362.1 0.2 0.5 4.8 0.4 0.6 1.4 1.4 1.5 1.2 10.0 0.0 12.9 6.2 0.0 0.0 0.1 29.4 2.4 39.5 2.8 9.2 6.1 3.0 2.7 147.4 4.2 0.1 6.4 0.5 8.4 0.0 18.7 10.8 2.5 0.2 1.7 171.1 0.2 0.0 1.6 0.9 16.9 7.5 0.7 7.2 89.0 0.0 16.7 0.0 390.6 76.6 2.0 0.1 12.8 0.4 12.4 0.2 4.5 0.1 2.9 0.0 13.3 4.5 3.2 7.8 0.0 0.9 0.3 0.6 29.6 0.1 1.3 PROK1 "EGVEGF, PK1, PRK1" ENSG00000143125 "Prokineticin 1" P58294 1 110451149-110457358 "Predicted secreted proteins" Angiogenesis "Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "ovary: 197.1;placenta: 50.2;testis: 59.1" "Group enriched" "Detected in some" 8 "Leydig cells: 173.1;Peritubular cells: 668.0" "Cancer enhanced" "Detected in many" "testis cancer: 4.7" "Region enhanced" "Detected in many" "medulla oblongata: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "ASC diff: 22.6" "Region enriched" "Detected in single" 11 "pons and medulla: 1.4" "Low region specificity" "Detected in many" "Secreted to blood" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "unprognostic (2.66e-1)" "unprognostic (2.71e-2)" "unprognostic (1.30e-1)" "unprognostic (1.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.26e-1)" "unprognostic (1.86e-1)" "unprognostic (3.86e-1)" "unprognostic (6.80e-2)" "unprognostic (1.24e-2)" "unprognostic (3.74e-2)" "unprognostic (7.39e-3)" "unprognostic (1.90e-1)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" 4.0 9.8 0.4 0.4 0.3 0.0 5.1 0.4 0.7 14.1 0.2 0.3 0.1 0.3 0.1 1.2 3.5 0.4 2.7 1.1 0.4 0.1 0.2 0.3 0.0 5.5 1.3 197.1 0.3 0.0 0.7 50.2 1.2 12.8 0.0 0.1 0.5 9.9 1.3 2.4 0.2 0.0 1.8 1.5 0.4 59.1 0.9 0.1 0.2 0.0 0.0 4.5 25.1 1.5 0.0 0.0 0.0 0.1 22.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.7 1.1 0.4 5.5 1.3 1.2 1.8 0.9 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.7 0.6 16.4 0.1 0.0 0.0 0.0 0.0 0.1 5.9 0.0 0.3 0.0 1.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 23.4 173.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 668.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.7 1.1 0.0 0.0 1.0 0.1 52.3 0.0 0.1 PRPH2 "CACD2, rd2, RDS, RP7, TSPAN22" ENSG00000112619 "Peripherin 2" P23942 6 42696598-42722597 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "retina: 641.4" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 260.6;Rod photoreceptor cells: 482.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.0;ASC TERT1: 3.4;fHDF/TERT166: 5.3;HHSteC: 7.8;HSkMC: 6.0;LHCN-M2: 3.5" "Region enriched" "Detected in single" 7 "hippocampal formation: 2.4" "Not detected" "Not detected" HPA029458 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA029458: AB_10602193" "unprognostic (2.37e-1)" "unprognostic (4.88e-2)" "unprognostic (6.67e-2)" "unprognostic (8.43e-2)" "unprognostic (1.15e-1)" "unprognostic (2.87e-3)" "unprognostic (4.73e-1)" "unprognostic (1.85e-1)" "unprognostic (6.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (3.18e-2)" "unprognostic (7.07e-4)" "unprognostic (1.13e-3)" "unprognostic (1.59e-1)" "unprognostic (8.42e-2)" "unprognostic (8.96e-3)" 1.1 0.8 2.1 0.5 1.5 0.0 0.5 0.4 1.8 2.0 0.1 2.2 0.4 2.1 1.8 0.7 1.3 1.1 1.5 3.1 2.1 1.4 0.2 1.5 0.1 0.9 1.0 3.1 2.3 4.3 2.5 0.9 1.2 1.5 0.8 641.4 0.7 1.1 13.2 0.3 1.4 1.9 0.4 0.8 1.2 3.7 2.7 0.2 4.1 2.9 0.1 1.2 1.1 1.2 0.0 0.0 0.0 0.0 3.0 3.4 0.7 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 7.8 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.2 0.0 0.1 0.0 2.1 1.5 0.4 1.8 3.1 2.1 0.9 1.0 1.2 0.4 2.7 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 39.3 0.1 0.0 0.9 0.0 0.1 0.0 260.6 0.1 0.0 0.0 3.9 0.3 0.2 0.1 0.9 2.3 0.0 0.0 2.3 0.2 0.0 1.3 0.0 0.1 0.0 0.2 0.4 0.2 0.0 11.8 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.9 0.0 42.6 1.0 0.5 0.6 0.5 0.0 1.9 0.0 0.2 0.0 0.2 0.0 482.7 0.0 0.9 0.8 2.3 0.5 0.1 0.3 0.1 0.0 1.3 0.0 0.1 PRRX1 "PHOX1, PMX1" ENSG00000116132 "Paired related homeobox 1" P54821 1 170662728-170739421 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 351.7;Endometrial stromal cells: 158.6;Fibroblasts: 180.2;Late spermatids: 390.0;Leydig cells: 256.3;Oligodendrocyte precursor cells: 288.5;Smooth muscle cells: 206.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 367.0;ASC TERT1: 290.5;BJ: 109.7;BJ hTERT+: 213.2;HSkMC: 150.6;U-138 MG: 146.0;U-2197: 140.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051084, HPA063566" Uncertain Supported Nucleoplasm NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA051084: AB_2681338, HPA063566: AB_2732702" "unprognostic (2.03e-1)" "unprognostic (2.00e-1)" "unprognostic (1.09e-1)" "unprognostic (7.00e-2)" "unprognostic (1.24e-1)" "unprognostic (4.97e-2)" "unprognostic (2.52e-2)" "unprognostic (1.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.60e-10)" "unprognostic (4.23e-3)" "unprognostic (4.48e-2)" "unprognostic (2.68e-3)" "unprognostic (1.69e-3)" 96.3 10.2 14.5 17.7 15.2 0.0 42.9 15.4 13.4 92.0 5.4 5.6 1.1 68.6 20.3 20.1 42.3 34.1 44.2 12.6 26.2 2.3 0.4 21.7 34.6 17.4 18.5 28.2 3.8 7.5 4.9 6.3 16.8 33.5 5.7 0.1 38.5 75.6 51.7 24.1 3.6 52.4 7.9 1.9 3.4 14.2 16.5 18.7 41.6 73.9 36.3 33.0 58.8 15.0 0.0 0.0 2.1 0.0 367.0 290.5 0.1 109.7 213.2 15.0 14.8 0.0 0.1 0.1 0.0 90.2 0.0 0.0 18.5 0.0 4.7 0.0 0.2 0.0 1.6 0.0 1.2 0.0 0.0 150.6 0.0 73.4 0.4 25.7 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.8 0.0 0.0 0.1 146.0 2.6 140.4 16.9 0.0 0.0 0.0 77.3 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 15.2 15.4 13.4 12.6 26.2 17.4 18.5 16.8 7.9 16.5 15.0 49.8 0.0 0.5 114.3 0.3 16.3 0.6 0.1 4.0 0.0 1.3 10.2 29.8 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 1.2 351.7 4.9 158.6 11.4 0.0 0.0 17.4 0.2 0.1 180.2 0.5 3.5 0.0 0.6 0.0 0.0 0.8 0.0 5.5 0.0 0.0 0.0 27.9 390.0 256.3 2.8 14.2 124.6 0.0 0.5 0.0 288.5 0.9 0.7 0.0 104.6 0.4 1.7 0.0 0.1 0.0 0.2 52.6 59.1 206.5 15.4 1.9 1.2 11.8 0.1 2.3 0.6 0.0 1.2 PRXL2A "Adrx, C10orf58, FAM213A, MGC4248, PAMM" ENSG00000122378 "Peroxiredoxin like 2A" Q9BRX8 10 80407829-80437115 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Antioxidant "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 405.6" "Group enriched" "Detected in some" 7 "Adipocytes: 161.4;Cardiomyocytes: 161.5;Hofbauer cells: 75.1;Smooth muscle cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 166.0" "Lineage enriched" "Detected in all" 11 "dendritic cells: 166.0" "Cell line enhanced" "Detected in many" "ASC diff: 947.9;HaCaT: 276.4;HUVEC TERT2: 436.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009025, HPA024565" Enhanced "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA009025: AB_1078312, HPA024565: AB_1845519" "unprognostic (1.73e-2)" "unprognostic (2.96e-2)" "unprognostic (6.96e-3)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (4.31e-2)" "unprognostic (3.14e-1)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (7.01e-2)" "unprognostic (3.54e-2)" "unprognostic (2.83e-3)" "unprognostic (3.32e-3)" "unprognostic (3.55e-1)" "unprognostic (6.78e-2)" "unprognostic (1.80e-1)" "prognostic favorable (6.11e-4)" 405.6 25.1 112.4 15.9 110.4 3.6 210.2 97.4 119.8 92.0 122.6 51.8 84.0 52.5 212.8 83.9 30.9 30.8 76.3 121.8 104.3 110.9 197.3 20.9 18.0 108.2 111.3 30.7 66.0 69.0 59.1 45.2 108.5 70.4 43.2 42.9 50.6 44.3 49.7 81.1 59.8 19.9 103.1 12.3 24.8 51.5 131.1 34.7 55.1 75.8 26.9 71.4 51.9 101.5 26.0 62.9 105.3 0.4 947.9 0.1 7.2 4.0 22.0 2.0 0.5 60.1 76.3 16.6 82.1 0.3 47.1 276.4 9.5 10.9 0.5 1.1 17.6 32.5 23.8 89.0 91.9 0.3 9.0 71.1 20.2 6.7 0.3 250.1 436.7 95.1 26.9 0.6 0.0 89.6 41.9 4.7 51.2 39.1 0.3 117.5 48.5 0.8 223.1 106.2 107.6 76.6 11.0 147.7 168.4 78.9 66.2 46.2 119.1 0.6 1.0 0.5 0.6 9.3 22.0 0.4 66.0 0.6 7.6 1.3 3.5 11.6 6.6 0.8 5.1 15.8 3.7 5.5 3.3 11.1 13.4 13.9 2.2 6.2 0.2 166.0 0.2 4.8 112.4 110.4 97.4 119.8 121.8 104.3 108.2 111.3 108.5 103.1 131.1 101.5 161.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.5 0.0 0.0 0.0 0.0 13.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 7.4 13.4 0.0 0.0 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.0 PRXL2C "AAED1, C9orf21" ENSG00000158122 "Peroxiredoxin like 2C" Q7RTV5 9 96639577-96655317 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 23.8;Cardiomyocytes: 18.3;Cytotrophoblasts: 15.7;dendritic cells: 22.5;Extravillous trophoblasts: 69.9;Hofbauer cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 45.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 45.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021294 Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA021294: AB_1845818" "unprognostic (4.17e-2)" "unprognostic (1.21e-1)" "unprognostic (6.37e-3)" "unprognostic (1.25e-1)" "unprognostic (4.35e-2)" "unprognostic (6.00e-2)" "unprognostic (1.85e-2)" "unprognostic (1.85e-1)" "unprognostic (1.63e-1)" "unprognostic (4.83e-2)" "unprognostic (4.50e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.13e-2)" "unprognostic (1.66e-1)" "unprognostic (8.38e-3)" "unprognostic (3.70e-2)" 13.3 5.6 3.5 6.1 3.8 11.5 10.1 3.6 4.3 6.5 3.9 7.6 3.7 8.0 2.9 5.5 8.0 8.4 13.8 3.7 3.7 5.5 6.9 9.7 4.9 5.2 4.0 5.0 6.0 3.2 3.1 6.4 5.0 5.3 4.2 1.2 3.9 3.7 11.3 4.9 5.6 10.9 4.4 7.1 5.5 5.2 4.4 3.4 8.2 7.9 5.3 8.5 5.2 5.0 11.0 5.6 2.7 9.6 22.5 38.4 10.7 12.1 18.1 10.0 9.6 12.7 12.2 0.3 9.8 19.8 19.4 10.4 9.5 5.8 6.0 11.3 5.9 6.3 4.9 10.5 17.2 5.1 17.3 18.3 10.0 7.0 8.8 9.9 8.8 4.4 12.6 4.6 10.4 7.8 0.2 9.0 3.7 4.5 10.5 0.2 8.0 0.2 14.2 2.5 4.3 5.4 8.8 7.4 6.5 8.0 2.9 9.0 16.1 16.8 7.0 16.4 8.0 12.2 5.8 4.2 7.2 4.7 15.7 45.7 9.6 23.2 10.1 11.4 10.6 10.1 9.4 10.1 8.7 7.6 4.9 8.2 2.0 5.8 11.1 5.6 10.6 3.5 3.5 3.8 3.6 4.3 3.7 3.7 5.2 4.0 5.0 4.4 4.4 5.0 23.8 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 15.7 22.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 69.9 10.7 0.0 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 6.3 8.9 0.0 0.0 0.0 PTGER2 EP2 ENSG00000125384 "Prostaglandin E receptor 2" P43116 14 52314305-52328598 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.4" "Cell type enhanced" "Detected in many" "dendritic cells: 55.6;Macrophages: 33.2;NK-cells: 177.1;T-cells: 63.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 26.1;ASC TERT1: 68.3;HHSteC: 43.8;HL-60: 25.2;HSkMC: 56.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.48e-1)" "unprognostic (2.48e-2)" "unprognostic (1.36e-2)" "unprognostic (4.04e-3)" "unprognostic (1.55e-2)" "unprognostic (3.24e-1)" "unprognostic (3.11e-3)" "unprognostic (1.79e-1)" "unprognostic (2.42e-1)" "unprognostic (1.20e-3)" "unprognostic (1.18e-1)" "unprognostic (1.83e-1)" "prognostic unfavorable (4.16e-4)" "unprognostic (8.48e-3)" "unprognostic (5.26e-3)" "unprognostic (6.71e-2)" "unprognostic (5.74e-2)" 8.7 1.4 0.1 12.6 0.6 38.4 3.6 0.0 0.4 17.2 3.0 8.0 6.2 9.4 0.6 1.8 4.6 9.7 1.1 0.1 0.2 3.2 3.6 5.4 4.5 0.7 0.5 8.2 1.2 0.4 0.7 14.4 0.3 9.9 6.6 0.0 3.2 2.8 0.7 1.3 9.4 5.1 0.6 11.8 17.5 2.9 0.3 3.2 1.7 0.3 1.7 5.8 2.2 0.3 1.3 0.5 0.0 0.0 26.1 68.3 0.1 2.1 0.4 2.3 2.8 0.0 0.1 0.0 1.8 1.4 0.0 9.3 0.0 0.5 3.3 0.0 13.2 0.0 0.7 0.0 43.8 25.2 0.3 56.2 1.1 5.8 0.9 7.4 0.0 0.0 0.0 0.0 13.4 1.2 0.0 1.0 1.0 4.5 8.8 0.2 0.0 0.0 20.6 0.1 0.7 20.6 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.9 1.5 15.5 0.0 0.0 0.0 0.0 6.1 14.2 0.2 5.8 35.9 35.5 106.7 30.6 129.3 0.2 91.0 114.3 19.0 0.1 21.7 67.7 4.7 73.5 61.5 0.9 50.0 66.3 0.1 0.6 0.0 0.4 0.1 0.2 0.7 0.5 0.3 0.6 0.3 0.3 4.0 3.2 1.7 0.0 3.2 1.8 0.4 0.8 1.2 0.0 2.0 2.5 1.2 1.5 0.7 3.7 0.0 0.1 55.6 0.7 0.0 0.3 0.0 24.0 1.6 0.9 6.0 3.0 0.1 0.0 0.3 13.9 15.3 7.7 20.8 2.9 4.2 0.6 10.0 0.0 0.1 6.0 0.0 28.0 19.6 0.5 4.1 33.2 3.6 0.0 16.6 0.0 177.1 0.0 0.0 1.5 0.1 3.0 3.7 1.4 0.0 0.3 9.6 0.0 0.0 1.3 11.6 0.1 1.2 0.2 1.6 0.3 63.1 0.2 0.6 0.2 PTGFR FP ENSG00000122420 "Prostaglandin F receptor" P43088 1 78303884-78540701 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 20.1" "Cell type enhanced" "Detected in many" "Club cells: 14.3;Fibroblasts: 22.7;Inhibitory neurons: 10.4;Langerhans cells: 10.6;Microglial cells: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "ASC TERT1: 271.2;HSkMC: 85.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.14e-2)" "unprognostic (1.35e-2)" "unprognostic (5.89e-3)" "unprognostic (6.03e-2)" "unprognostic (5.63e-2)" "unprognostic (1.45e-3)" "unprognostic (7.61e-2)" "unprognostic (2.25e-1)" "unprognostic (9.90e-2)" "unprognostic (8.46e-4)" "unprognostic (2.21e-1)" "unprognostic (5.34e-2)" "unprognostic (2.16e-4)" "unprognostic (3.21e-4)" "unprognostic (8.48e-2)" "unprognostic (2.16e-2)" "unprognostic (1.21e-3)" 9.9 3.4 0.6 5.7 0.4 0.0 7.2 0.1 1.8 4.6 0.3 2.0 1.0 17.9 2.4 0.9 4.6 6.9 1.7 1.9 2.7 3.9 1.3 2.5 1.2 0.7 0.5 4.6 0.9 0.0 0.2 8.1 1.8 3.1 2.7 0.2 4.7 2.0 2.1 5.2 2.4 16.7 0.4 0.6 1.6 1.4 3.5 0.1 0.8 20.1 4.3 11.9 4.4 0.2 0.0 0.0 1.0 0.0 26.5 271.2 0.0 20.5 20.0 7.0 2.7 0.0 0.0 0.0 0.0 12.4 3.8 0.0 0.0 0.1 6.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 85.7 0.0 1.8 17.6 18.3 0.1 0.0 0.0 0.7 10.9 0.0 0.0 0.0 0.1 0.0 15.9 0.0 0.0 0.0 2.4 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.2 5.9 8.5 4.7 2.1 1.6 1.1 0.0 0.0 0.5 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.1 1.8 1.9 2.7 0.7 0.5 1.8 0.4 3.5 0.2 1.2 0.0 8.0 0.3 0.0 6.4 0.0 1.0 0.0 1.2 0.2 0.0 0.4 5.7 14.3 9.2 0.0 0.1 0.0 0.0 3.9 4.2 8.5 0.4 0.6 0.6 0.0 0.0 0.4 0.0 0.0 22.7 0.5 0.1 0.0 0.1 0.0 2.3 0.1 0.0 10.4 0.0 0.0 0.0 10.6 9.3 5.6 0.4 5.4 17.8 0.0 0.3 0.0 0.0 0.2 0.0 1.1 0.4 0.2 0.1 0.0 0.3 6.3 0.0 6.6 7.1 1.4 1.1 0.2 0.1 4.7 0.3 0.5 0.3 0.0 0.0 PTPRA "HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA" ENSG00000132670 "Protein tyrosine phosphatase receptor type A" P18433 20 2864184-3039076 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029412, CAB034366, HPA069480" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB034366: AB_2269058, HPA029412: AB_10602293, HPA069480: AB_2686141" "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" "unprognostic (4.58e-2)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (5.43e-3)" "unprognostic (5.34e-2)" "unprognostic (1.55e-1)" "unprognostic (3.24e-1)" "unprognostic (7.33e-2)" "unprognostic (1.16e-1)" "prognostic favorable (3.29e-6)" "unprognostic (1.25e-1)" "unprognostic (4.02e-1)" "unprognostic (1.60e-2)" "unprognostic (4.19e-1)" 48.8 36.6 83.9 31.9 89.3 39.6 47.4 84.2 96.1 56.4 59.5 41.6 31.0 53.0 36.7 46.1 52.7 43.7 29.5 87.7 83.5 44.2 28.6 45.4 38.9 74.7 81.9 55.8 31.2 81.9 44.8 60.8 78.3 46.3 40.6 61.5 36.3 41.9 16.9 45.8 32.7 52.4 76.3 39.4 34.5 43.4 92.6 59.6 65.5 30.7 44.3 46.6 38.9 81.1 74.0 44.2 124.7 38.4 134.4 243.3 26.5 54.1 105.1 65.5 79.6 53.1 99.5 48.1 41.6 73.1 66.1 77.2 51.0 77.4 73.4 74.7 32.7 68.5 18.3 68.0 48.1 69.5 31.1 109.8 78.2 54.4 56.8 80.3 92.0 67.7 69.9 59.7 65.8 30.4 80.8 78.3 48.3 66.0 35.0 61.0 60.5 60.3 55.1 56.2 68.7 65.7 52.3 87.8 81.4 54.0 55.2 58.7 66.5 58.1 28.6 65.6 48.5 43.4 64.7 62.7 26.9 64.5 55.7 5.7 2.8 4.8 6.1 2.9 4.9 5.3 4.0 4.4 2.1 2.6 4.0 4.8 3.3 4.0 4.3 3.2 4.9 2.3 83.9 89.3 84.2 96.1 87.7 83.5 74.7 81.9 78.3 76.3 92.6 81.1 87.0 22.4 19.2 128.6 46.7 15.8 34.0 15.0 34.7 88.9 49.0 43.9 10.1 54.3 24.5 46.0 31.3 35.3 111.7 39.8 27.4 14.8 17.0 62.0 109.0 39.7 44.3 42.3 138.2 15.8 40.5 67.5 25.0 55.3 22.9 60.3 43.5 33.6 39.4 70.7 136.4 27.9 24.4 37.6 20.4 17.2 60.3 40.1 37.4 52.5 29.9 88.3 110.2 102.5 147.5 16.6 30.2 48.9 58.6 32.9 27.1 23.6 26.6 60.5 39.5 53.3 61.8 68.7 84.1 32.9 17.2 32.7 59.7 41.4 30.4 31.5 PTPRG "PTPG, RPTPG" ENSG00000144724 "Protein tyrosine phosphatase receptor type G" P23470 3 61561569-62297609 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 356.8;Excitatory neurons: 416.1;Inhibitory neurons: 684.3;Microglial cells: 771.0;Oligodendrocyte precursor cells: 920.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 81.7;HSkMC: 61.1" "Low region specificity" "Detected in all" "HPA000546, HPA064237" Uncertain Approved "Plasma membrane" NA NA 520000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA000546: , HPA064237: AB_2685221" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (3.26e-1)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (5.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-1)" "prognostic favorable (3.10e-6)" "unprognostic (9.91e-2)" "unprognostic (3.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" 18.0 13.2 7.6 4.6 7.8 0.0 12.8 4.9 10.4 11.9 23.4 8.2 3.7 10.6 8.4 4.1 9.0 8.3 10.0 13.7 6.2 14.4 5.8 12.8 1.8 8.4 7.2 12.0 3.9 26.6 5.2 9.9 5.9 7.8 6.1 8.6 5.2 8.4 7.4 4.5 5.9 13.0 10.0 7.0 5.8 7.7 9.1 2.1 13.1 10.4 1.7 7.0 6.7 5.0 0.0 5.3 27.3 0.0 81.7 41.6 13.5 17.6 28.5 18.2 24.4 13.2 0.5 0.6 10.1 20.7 14.5 0.2 13.4 13.6 28.3 1.5 7.7 1.4 0.1 15.0 27.5 7.5 0.1 61.1 5.3 25.9 30.9 5.8 19.7 2.0 0.0 17.3 16.3 7.6 0.0 0.1 17.0 0.1 0.0 11.9 8.6 0.6 18.2 8.2 2.1 4.5 4.3 0.1 6.9 11.2 0.2 0.3 46.0 25.4 24.1 41.0 14.7 5.5 6.8 0.0 19.2 3.2 31.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.6 7.8 4.9 10.4 13.7 6.2 8.4 7.2 5.9 10.0 9.1 5.0 45.3 12.8 32.4 356.8 2.2 9.2 6.4 5.0 13.1 98.5 9.6 6.3 12.5 8.6 5.8 22.0 6.2 10.5 0.9 12.1 5.9 9.6 3.6 14.4 31.9 55.5 24.6 0.0 416.1 1.8 0.8 47.7 4.1 30.5 0.0 64.6 90.3 32.7 19.7 154.8 684.3 8.9 22.4 2.9 8.8 4.3 66.5 1.1 17.8 771.0 0.6 40.8 2.1 920.3 11.8 5.3 5.6 56.8 4.2 10.9 13.9 18.2 2.8 5.7 72.3 81.1 60.6 2.0 8.6 2.1 4.8 12.6 2.3 20.0 12.1 2.7 PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase receptor type M" P28827 18 7566782-8406861 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 142.0;Astrocytes: 188.1;Inhibitory neurons: 751.6;Microglial cells: 263.3;Oligodendrocyte precursor cells: 224.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 4.7" "Group enriched" "Detected in many" 33 "dendritic cells: 1.8;T-cells: 4.7" "Cell line enhanced" "Detected in many" "ASC diff: 98.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Approved "Plasma membrane" NA Yes 130000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB022442: , CAB022443: , HPA003891: AB_2667073" "unprognostic (2.59e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.41e-2)" "unprognostic (7.62e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-2)" "unprognostic (9.64e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.63e-2)" "prognostic favorable (1.07e-4)" 53.1 24.1 18.9 11.9 37.6 1.2 41.8 13.0 27.7 18.4 44.2 25.3 8.7 24.2 11.9 14.2 23.3 32.4 61.2 12.7 38.7 29.5 11.8 38.9 15.5 21.7 53.0 26.4 13.2 23.4 16.1 33.2 34.3 16.7 11.5 19.3 10.9 36.0 52.5 12.3 15.1 24.8 5.8 23.1 18.4 22.8 47.6 16.7 54.8 63.4 11.9 23.9 12.2 14.4 4.6 33.4 15.7 0.2 98.0 67.4 38.7 41.1 35.6 26.9 39.5 30.9 7.1 0.0 39.0 49.1 0.5 0.3 0.2 14.3 36.9 0.5 7.2 0.0 22.2 15.2 27.9 0.0 0.4 77.1 29.3 14.9 42.1 51.1 27.2 0.0 0.0 13.8 21.8 0.7 13.7 0.3 2.6 9.9 7.3 0.5 13.5 63.9 64.9 57.6 1.4 8.6 1.1 0.2 34.6 24.9 0.2 0.0 28.2 54.9 34.6 26.4 7.2 1.1 0.4 0.3 46.8 0.2 10.4 0.0 0.0 0.0 2.8 0.0 1.1 0.0 3.8 4.7 0.0 0.0 1.0 2.0 0.0 0.0 0.0 1.8 0.7 1.1 18.9 37.6 13.0 27.7 12.7 38.7 21.7 53.0 34.3 5.8 47.6 14.4 142.0 44.8 36.0 188.1 1.1 6.0 7.3 3.0 2.8 28.3 2.5 3.2 26.7 14.3 7.1 5.5 2.1 11.4 5.4 0.9 1.9 17.6 25.9 28.9 15.6 68.9 1.8 0.4 70.1 8.3 3.4 14.0 8.2 59.6 2.5 13.0 47.2 25.3 9.9 0.0 751.6 1.4 0.0 8.0 5.7 42.0 2.8 5.1 30.2 263.3 0.6 2.9 3.1 224.7 50.3 14.3 1.2 5.3 2.3 8.3 3.0 13.3 15.6 2.2 6.6 7.4 9.9 8.6 9.9 0.9 2.8 12.6 5.7 3.7 0.8 8.6 PYGM GSD5 ENSG00000068976 "Glycogen phosphorylase, muscle associated" P11217 11 64746389-64759974 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 65 "skeletal muscle: 8468.3;tongue: 3594.2" "Cell type enhanced" "Detected in many" "Astrocytes: 29.7;Cardiomyocytes: 47.5;Late spermatids: 49.2;Peritubular cells: 44.0;Skeletal myocytes: 64.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 8.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 8.1" "Cell line enhanced" "Detected in some" "HSkMC: 3.7;NB-4: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056003 Enhanced NA NA 10000000 "Cluster 10: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "HPA056003: AB_2683006" "unprognostic (3.33e-1)" "unprognostic (6.03e-3)" "unprognostic (3.87e-4)" "unprognostic (1.95e-3)" "unprognostic (8.71e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (2.92e-1)" "unprognostic (3.88e-1)" "unprognostic (3.08e-2)" "unprognostic (1.12e-1)" "unprognostic (2.64e-1)" "unprognostic (6.33e-6)" "unprognostic (3.37e-3)" "unprognostic (1.81e-1)" "unprognostic (1.62e-2)" "unprognostic (5.68e-2)" 15.2 3.0 35.4 2.1 30.1 1.2 7.7 55.5 29.4 5.8 15.5 25.5 1.5 10.4 6.4 92.2 14.6 3.8 70.8 26.8 26.1 2.4 1.2 2.7 2.2 48.8 30.4 4.0 1.6 0.3 1.7 1.4 39.6 25.6 3.6 2.9 50.0 26.3 8468.3 4.2 7.0 14.7 44.9 3.3 6.9 6.7 47.3 1.3 5.2 3594.2 1.2 16.7 5.2 38.1 0.1 0.0 0.7 0.1 0.5 0.7 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.6 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.6 0.1 0.3 0.2 0.0 0.3 0.4 0.1 3.7 0.2 0.2 0.1 0.0 0.0 1.1 0.7 0.6 0.0 1.1 0.7 2.2 0.7 0.1 0.1 0.4 0.7 0.1 0.0 0.1 0.2 0.0 0.2 0.3 0.4 0.4 0.3 0.4 0.3 0.0 0.4 0.1 0.0 1.0 1.4 0.4 0.0 0.1 0.0 8.1 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 1.1 0.0 0.1 0.1 1.3 0.0 0.2 0.2 0.1 35.4 30.1 55.5 29.4 26.8 26.1 48.8 30.4 39.6 44.9 47.3 38.1 2.4 0.0 2.3 29.7 3.0 0.8 0.6 0.2 5.2 3.5 2.9 4.7 47.5 0.0 0.8 0.0 4.2 0.6 1.9 1.0 0.0 0.1 11.7 1.6 5.2 2.0 0.0 0.0 0.2 0.0 0.2 5.1 1.1 4.0 0.0 0.8 1.8 0.0 0.5 0.0 0.2 0.9 0.0 0.6 1.3 49.2 16.4 2.3 0.0 1.0 0.5 9.9 4.1 0.5 0.4 0.3 0.2 44.0 0.3 1.3 0.6 0.0 0.1 1.3 6.6 64.3 12.8 1.2 0.9 2.5 0.6 0.1 2.9 0.9 1.1 0.3 RAB10 ENSG00000084733 "RAB10, member RAS oncogene family" P61026 2 26034084-26137454 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 488.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045611 Approved NA Yes 4300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA045611: AB_10961124" "unprognostic (7.73e-3)" "unprognostic (2.45e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (7.40e-4)" "unprognostic (8.22e-3)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.99e-5)" "unprognostic (9.22e-3)" "unprognostic (6.14e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (7.37e-5)" "unprognostic (1.06e-2)" "unprognostic (8.69e-3)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.99e-2)" 47.4 51.5 42.8 44.2 49.0 17.7 45.1 48.7 56.7 55.6 29.7 58.8 41.3 38.9 40.3 172.9 39.6 41.9 49.8 41.2 47.3 56.8 48.5 39.9 42.8 52.9 46.9 37.1 37.7 66.3 21.5 40.9 54.4 42.6 57.9 29.0 51.7 41.6 213.9 71.0 46.3 48.1 51.5 44.4 58.8 24.0 46.4 43.8 54.2 114.0 64.5 78.5 78.1 62.8 117.1 139.7 63.8 53.1 131.2 108.2 61.9 90.3 76.8 69.7 61.6 83.2 83.8 77.9 83.4 96.7 79.5 62.0 77.3 84.4 73.9 82.3 56.0 135.1 54.4 134.8 122.6 112.2 73.5 89.0 135.9 85.9 100.3 109.6 89.0 48.9 114.1 76.7 95.1 52.0 69.1 87.1 65.2 139.5 81.7 65.2 133.4 132.8 141.6 111.8 90.1 83.7 75.2 135.1 94.9 70.5 59.5 80.1 110.2 107.1 56.2 75.7 97.2 50.5 84.2 124.4 107.9 132.6 83.5 58.0 75.5 35.5 31.5 135.2 38.6 33.4 36.9 34.1 69.9 32.0 31.1 35.2 54.6 50.6 152.6 24.3 44.6 81.0 42.8 49.0 48.7 56.7 41.2 47.3 52.9 46.9 54.4 51.5 46.4 62.8 70.8 80.1 49.7 37.9 56.2 341.8 195.5 156.4 122.3 23.8 85.2 64.6 76.4 85.8 134.7 92.0 8.4 121.0 48.7 168.8 115.4 188.3 35.5 67.8 76.7 78.4 65.2 101.0 43.6 96.0 204.4 80.7 97.3 98.3 50.7 44.0 53.2 66.8 159.7 26.9 36.0 94.1 107.8 157.2 285.1 29.6 62.7 151.6 88.9 36.5 246.8 104.9 38.1 47.7 78.1 136.8 123.8 70.0 63.6 199.7 85.9 135.2 107.4 32.7 85.5 94.1 159.5 85.3 73.4 255.9 488.0 128.3 59.3 65.6 117.7 334.3 RAB13 ENSG00000143545 "RAB13, member RAS oncogene family" P51153 1 153981617-153986358 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 7.0;myeloid DC: 10.5;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 11 "dendritic cells: 12.9;monocytes: 7.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 846.1" HPA003996 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA003996: AB_1079728" "unprognostic (4.39e-3)" "unprognostic (1.20e-1)" "unprognostic (2.51e-2)" "unprognostic (4.11e-2)" "unprognostic (4.28e-3)" "unprognostic (3.20e-2)" "unprognostic (1.18e-3)" "unprognostic (2.80e-1)" "unprognostic (3.53e-2)" "unprognostic (2.11e-2)" "unprognostic (2.10e-1)" "unprognostic (5.93e-2)" "unprognostic (1.06e-3)" "unprognostic (2.45e-1)" "unprognostic (1.03e-1)" "unprognostic (9.51e-3)" "unprognostic (1.28e-2)" 151.4 132.8 78.8 91.0 80.1 104.3 124.1 79.4 112.4 114.1 89.2 123.6 54.1 92.2 111.3 102.0 96.0 83.3 90.1 77.3 88.6 164.6 111.1 116.8 42.5 92.5 85.3 111.1 115.1 97.9 35.4 64.3 89.7 123.5 73.6 10.5 96.3 73.5 45.9 92.1 79.0 67.5 84.7 97.5 123.3 61.7 84.0 19.2 112.8 49.5 47.7 123.2 107.7 83.7 133.4 162.5 143.7 152.8 478.2 846.1 43.2 157.9 381.1 142.6 144.6 165.4 111.9 0.1 230.7 194.4 72.7 88.4 86.9 146.7 198.0 78.6 62.3 110.1 100.5 94.3 199.5 0.4 70.9 620.1 125.3 246.6 109.1 401.0 253.4 0.0 20.6 0.5 246.6 280.0 0.5 55.4 231.8 183.9 151.2 28.9 186.1 0.1 327.0 140.5 7.2 112.6 208.7 179.8 337.0 215.4 294.2 87.0 469.6 256.0 149.5 161.1 174.7 0.4 0.1 0.9 399.6 17.4 399.7 0.0 7.0 0.1 0.0 1.0 0.1 0.7 0.1 0.0 10.5 0.6 0.1 0.4 0.8 0.0 0.1 12.9 0.0 1.9 78.8 80.1 79.4 112.4 77.3 88.6 92.5 85.3 89.7 84.7 84.0 83.7 230.1 41.7 83.4 1.0 9.0 92.0 181.3 196.3 110.4 1.2 126.9 149.2 75.2 120.1 105.3 108.5 2.1 116.3 2.8 81.5 135.0 234.4 119.9 91.9 163.2 239.8 89.1 116.4 0.0 149.2 181.2 100.8 76.5 111.4 40.6 111.9 192.4 136.2 249.1 0.0 0.0 184.2 83.4 111.1 104.5 232.1 106.2 116.0 99.6 7.5 247.4 71.5 2.1 0.0 0.1 158.1 110.6 124.1 10.6 197.0 135.7 206.5 72.2 3.8 151.2 46.9 151.4 103.6 18.4 124.8 98.2 92.9 8.9 141.6 146.1 195.9 RAI2 ENSG00000131831 "Retinoic acid induced 2" Q9Y5P3 X 17800049-17861337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 41.9;Leydig cells: 49.0;Peritubular cells: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.8" "Lineage enriched" "Detected in single" 10 "T-cells: 1.8" "Cell line enriched" "Detected in some" 10 "ASC diff: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051054 Uncertain Approved "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA051054: AB_2681328" "unprognostic (3.45e-2)" "unprognostic (9.61e-2)" "unprognostic (2.41e-1)" "unprognostic (2.03e-2)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (4.10e-2)" "unprognostic (2.51e-2)" "unprognostic (1.44e-1)" "unprognostic (1.49e-1)" "prognostic favorable (2.77e-4)" "unprognostic (1.31e-2)" "prognostic favorable (3.39e-14)" "unprognostic (1.57e-2)" "unprognostic (2.33e-1)" "unprognostic (1.82e-2)" "unprognostic (2.80e-2)" 48.0 17.3 9.4 8.3 10.4 0.2 47.2 8.8 11.9 55.3 7.4 33.0 6.7 66.8 9.9 15.5 71.8 24.7 32.9 9.9 9.3 14.4 3.9 28.6 9.6 9.4 8.5 50.9 14.3 10.8 19.3 7.8 9.6 31.8 8.1 8.9 13.8 31.8 12.5 20.3 23.0 30.1 8.6 4.5 28.2 6.0 10.4 5.0 21.6 17.1 9.6 38.9 43.7 8.7 0.0 0.0 0.2 0.0 104.3 10.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.7 0.2 0.6 0.0 0.1 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 0.1 1.9 0.0 0.6 0.0 0.0 0.0 5.8 0.0 1.1 1.4 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 1.8 0.0 0.1 0.0 0.0 0.0 0.1 9.4 10.4 8.8 11.9 9.9 9.3 9.4 8.5 9.6 8.6 10.4 8.7 25.0 12.8 4.5 2.0 0.0 4.1 9.3 0.0 0.6 14.0 13.4 10.4 13.0 12.8 0.6 22.0 0.0 0.1 0.3 0.3 5.9 8.2 0.3 25.0 16.5 15.2 27.6 0.0 10.5 9.8 0.1 24.8 7.7 41.9 0.0 9.7 10.8 0.1 0.5 26.9 17.9 0.7 0.0 0.0 4.2 3.3 49.0 0.9 5.4 14.0 0.6 20.5 0.0 5.0 0.4 4.9 17.5 70.7 0.1 7.9 1.3 1.9 4.4 3.0 0.0 21.0 8.7 0.4 2.7 0.5 2.8 0.0 1.3 0.2 1.6 5.1 RAMP2 ENSG00000131477 "Receptor activity modifying protein 2" O60895 17 42758447-42763041 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 1066.8;Endothelial cells: 562.9;Hepatic stellate cells: 344.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 21 "dendritic cells: 2.9" "Cell line enhanced" "Detected in many" "ASC diff: 120.4;EFO-21: 80.5;HUVEC TERT2: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052020 Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA052020: AB_2681697" "unprognostic (8.64e-2)" "unprognostic (2.12e-2)" "unprognostic (8.03e-2)" "unprognostic (1.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (6.79e-2)" "unprognostic (1.28e-2)" "unprognostic (6.96e-3)" "unprognostic (4.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.25e-1)" 190.0 29.0 60.4 19.2 61.8 0.1 168.9 61.7 72.3 100.7 67.7 35.7 12.5 63.1 27.8 25.1 51.7 39.6 123.2 59.3 65.8 70.5 16.7 163.3 26.2 65.7 68.1 33.0 17.1 23.8 20.8 97.0 72.7 42.1 21.1 4.1 45.9 27.5 43.3 55.9 44.1 72.6 62.7 40.2 33.9 11.9 66.6 11.4 71.7 98.7 24.5 45.9 49.6 62.4 0.1 1.1 4.9 0.1 120.4 6.2 4.0 0.9 2.1 10.2 4.9 11.5 0.1 0.0 80.5 3.0 0.5 0.0 4.6 0.1 8.9 0.0 0.2 0.0 0.7 3.7 3.0 0.0 0.0 4.2 0.1 1.8 0.4 3.5 37.6 1.5 0.1 0.2 0.6 0.0 0.6 0.8 23.3 0.0 0.0 0.1 0.1 0.0 0.6 0.6 4.8 9.8 2.9 0.0 17.3 4.8 1.2 3.2 6.7 19.3 7.1 0.4 2.4 0.0 0.1 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 60.4 61.8 61.7 72.3 59.3 65.8 65.7 68.1 72.7 62.7 66.6 62.4 1066.8 0.0 5.7 1.6 6.2 34.4 5.4 0.9 9.6 0.6 24.0 24.8 2.2 0.0 1.0 3.7 0.0 1.1 3.7 0.1 3.9 0.6 1.6 22.2 52.8 562.9 4.2 0.0 0.2 0.7 1.7 126.9 3.1 38.5 0.0 1.4 344.8 1.3 3.4 0.0 1.0 0.2 20.3 8.4 40.5 3.6 38.8 4.1 23.2 45.0 2.6 15.5 0.0 1.5 0.3 0.0 0.0 21.8 5.2 4.8 0.0 1.0 0.1 1.8 6.6 10.5 26.3 26.6 59.1 2.6 27.6 1.5 4.0 14.0 0.1 4.3 RANBP3L FLJ25422 ENSG00000164188 "RAN binding protein 3 like" Q86VV4 5 36246913-36302114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.9;kidney: 24.6" "Cell type enriched" "Detected in some" 7 "Astrocytes: 355.9" "Group enriched" "Detected in some" 5 "breast cancer: 1.4;glioma: 3.7;prostate cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "ASC diff: 12.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA037471, HPA037472, HPA061526" Approved Uncertain Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA037471: AB_10671756, HPA037472: AB_2675489, HPA061526: AB_2684552" "unprognostic (1.19e-1)" "unprognostic (1.02e-1)" "unprognostic (1.27e-1)" "unprognostic (1.41e-3)" "unprognostic (5.52e-3)" "unprognostic (2.85e-1)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (9.56e-2)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "unprognostic (1.28e-1)" "unprognostic (3.76e-4)" "unprognostic (1.68e-2)" "unprognostic (9.13e-2)" "unprognostic (8.87e-3)" "unprognostic (5.71e-2)" 3.8 1.7 25.2 0.3 27.0 0.0 7.6 4.6 29.9 1.2 5.4 0.8 0.2 0.7 1.8 0.5 1.2 1.8 1.5 25.1 12.2 24.6 9.9 2.0 0.2 9.9 18.9 2.1 0.4 0.2 2.9 5.0 7.4 13.5 0.4 5.3 0.6 2.9 0.4 0.4 0.4 0.6 12.6 0.2 1.8 4.7 18.6 0.1 2.2 2.9 0.6 6.9 0.8 15.2 0.0 0.0 0.1 0.2 12.1 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 27.0 4.6 29.9 25.1 12.2 9.9 18.9 7.4 12.6 18.6 15.2 0.3 0.0 0.0 355.9 0.0 0.0 0.1 0.0 0.6 0.4 4.1 2.3 0.3 0.0 0.0 9.2 0.0 0.0 1.3 0.0 46.9 0.0 0.1 0.1 0.7 0.4 0.0 0.0 5.1 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.4 1.3 1.9 0.0 4.5 0.0 0.0 0.0 0.3 0.8 2.1 0.2 1.8 23.4 0.0 16.1 0.0 5.5 2.8 0.0 0.0 2.2 0.0 1.3 0.0 0.2 0.0 0.6 13.1 0.6 8.3 0.0 0.1 0.0 0.0 0.1 0.0 3.0 0.0 0.1 RASD1 "AGS1, DEXRAS1" ENSG00000108551 "Ras related dexamethasone induced 1" Q9Y272 17 17494437-17496395 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 371.9" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 425.1;Muller glia cells: 375.3;Peritubular cells: 469.8;Sertoli cells: 565.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 46 "plasmacytoid DC: 160.1" "Lineage enriched" "Detected in many" 46 "dendritic cells: 160.1" "Group enriched" "Detected in some" 4 "ASC diff: 70.2;REH: 71.0" "Group enriched" "Detected in all" 5 "basal ganglia: 75.6;hippocampal formation: 54.9;thalamus: 53.2" "Low region specificity" "Detected in all" HPA047896 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "HPA047896: AB_10960535" "unprognostic (1.59e-1)" "unprognostic (1.32e-1)" "unprognostic (3.28e-2)" "unprognostic (3.31e-2)" "unprognostic (6.40e-2)" "unprognostic (8.13e-2)" "unprognostic (8.65e-2)" "unprognostic (7.60e-2)" "unprognostic (5.50e-2)" "unprognostic (2.11e-1)" "unprognostic (3.17e-3)" "unprognostic (2.92e-1)" "unprognostic (7.40e-2)" "unprognostic (1.11e-2)" "unprognostic (1.38e-1)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" 244.7 53.5 48.7 5.9 63.7 9.3 153.3 31.1 83.6 69.2 13.4 16.1 5.4 22.8 11.9 11.7 32.7 12.6 91.0 60.8 61.9 181.7 271.3 25.4 3.0 71.6 49.8 53.7 30.1 4.2 371.9 1.3 39.4 32.7 6.5 47.7 97.8 55.7 183.1 44.1 12.2 3.4 45.7 18.6 42.2 47.7 40.4 13.1 88.4 103.0 1.2 16.6 26.3 53.6 0.0 0.3 0.3 0.0 70.2 3.8 0.3 0.9 1.4 0.1 0.2 3.0 0.0 0.0 8.0 0.3 0.0 0.2 0.3 0.0 0.1 0.1 0.9 0.3 0.3 8.3 0.5 0.1 0.3 17.1 0.0 0.7 0.0 0.0 0.3 0.2 0.0 0.0 0.2 7.5 13.8 1.3 1.4 1.3 4.5 71.0 0.1 0.1 1.5 0.0 12.9 0.4 1.1 0.9 16.3 2.1 0.1 0.1 4.1 0.1 0.7 0.5 0.2 14.5 0.6 0.2 0.4 0.0 0.5 0.0 0.4 0.0 0.4 3.5 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.8 160.1 0.1 1.0 48.7 63.7 31.1 83.6 60.8 61.9 71.6 49.8 39.4 45.7 40.4 53.6 172.2 28.9 36.8 21.2 11.0 17.2 96.2 46.6 27.3 51.4 106.9 147.2 71.2 20.0 33.5 149.0 4.2 3.3 45.8 42.9 13.7 93.5 2.7 150.9 264.2 31.1 222.4 0.4 15.0 1.3 2.2 191.1 86.6 425.1 8.8 40.3 9.7 21.6 3.6 6.7 5.2 262.7 260.4 3.1 22.2 8.1 109.6 27.3 30.2 1.9 2.2 375.3 0.0 17.1 1.6 9.0 21.8 469.8 56.1 73.3 16.8 13.8 7.2 23.8 565.4 228.1 191.7 1.7 3.0 54.8 13.2 6.7 27.0 73.7 32.9 20.0 RASL11A ENSG00000122035 "RAS like family 11 member A" Q6T310 13 27270830-27275192 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 29.6;Fibroblasts: 30.1;Gastric mucus-secreting cells: 42.3;Sertoli cells: 32.9;Smooth muscle cells: 112.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 4 "ASC diff: 42.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA004859, HPA053296" Supported Approved "Nuclear bodies" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear bodies" "HPA004859: AB_2667270, HPA053296: AB_2682106" "unprognostic (1.59e-1)" "unprognostic (9.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (2.09e-2)" "unprognostic (6.65e-2)" "prognostic favorable (5.43e-4)" "unprognostic (3.85e-1)" "unprognostic (7.98e-2)" "unprognostic (2.65e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.52e-4)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" "unprognostic (3.71e-2)" "unprognostic (3.34e-1)" 32.9 4.1 1.9 3.1 3.2 2.3 21.8 3.1 3.1 21.4 2.1 20.4 7.7 21.6 3.9 9.8 22.0 3.8 11.3 3.2 1.7 30.4 12.9 13.0 10.8 1.8 2.2 9.5 4.9 1.4 10.6 2.9 2.0 20.3 12.5 0.1 5.3 5.6 3.5 10.1 20.9 5.5 2.2 14.8 13.4 2.9 3.3 1.2 12.1 1.7 10.0 19.1 15.9 2.4 0.3 1.3 0.3 0.6 42.4 4.3 0.2 1.9 1.8 0.1 0.1 8.1 0.8 0.3 0.5 1.4 0.9 0.1 2.5 0.8 0.1 1.7 8.8 1.8 0.2 0.5 6.8 0.6 0.6 5.0 0.7 0.1 0.1 1.7 0.6 0.7 0.3 0.1 0.0 0.8 0.0 2.4 1.5 8.0 10.2 0.5 0.0 0.2 1.4 6.2 0.7 0.3 0.7 3.3 0.2 1.0 0.2 0.8 0.3 0.1 0.3 2.9 0.4 0.1 0.0 0.0 0.4 1.9 0.1 0.4 0.4 0.4 0.0 0.5 0.1 0.1 0.0 0.0 0.2 1.2 0.1 0.1 0.2 0.1 1.3 0.1 0.0 0.1 1.9 3.2 3.1 3.1 3.2 1.7 1.8 2.2 2.0 2.2 3.3 2.4 29.6 16.0 11.2 0.3 6.0 4.6 3.2 0.9 17.6 0.0 6.2 11.9 1.4 0.0 8.6 7.3 0.0 0.7 4.5 9.3 3.9 1.8 0.0 5.1 9.8 5.9 0.0 4.0 0.6 2.4 0.2 30.1 42.3 6.1 0.0 2.1 2.5 0.2 1.4 0.0 0.6 5.6 4.1 0.8 6.5 0.0 0.3 6.1 1.8 1.9 1.7 0.3 0.0 0.5 1.8 0.5 12.7 1.5 17.1 1.1 11.4 1.7 10.3 0.2 32.9 11.6 112.0 0.0 0.0 13.5 4.4 0.8 4.5 1.2 6.7 1.1 RBL2 "p130, Rb2" ENSG00000103479 "RB transcriptional corepressor like 2" Q08999 16 53433977-53491648 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 468.3;Late spermatids: 209.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016547, HPA019703" Supported Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Cytosol" Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nucleoli rim, Mitotic chromosome" Cytosol "CAB016547: AB_785011, HPA019703: AB_1856106" "unprognostic (1.51e-1)" "unprognostic (4.38e-2)" "unprognostic (4.00e-2)" "unprognostic (1.26e-1)" "unprognostic (6.88e-2)" "unprognostic (6.43e-2)" "unprognostic (5.03e-2)" "unprognostic (2.46e-2)" "unprognostic (1.04e-1)" "unprognostic (2.11e-1)" "unprognostic (4.70e-1)" "unprognostic (8.12e-2)" "prognostic favorable (3.57e-5)" "unprognostic (9.57e-3)" "unprognostic (1.02e-1)" "unprognostic (8.70e-2)" "unprognostic (7.51e-2)" 32.5 25.4 11.1 32.3 13.6 19.1 31.7 12.5 10.4 33.5 14.8 26.6 23.3 32.2 20.2 25.0 31.8 27.7 25.6 8.7 10.5 39.2 59.5 38.9 49.7 12.3 12.0 37.8 39.0 62.7 17.7 19.3 13.0 42.9 29.3 23.1 34.2 39.9 32.4 26.3 26.1 30.7 11.7 41.0 32.6 48.4 11.4 66.6 40.2 37.7 51.2 30.9 28.9 16.9 25.9 18.1 20.7 20.6 61.2 57.9 9.4 17.8 26.4 23.1 7.9 10.1 30.9 39.0 28.4 32.8 22.3 29.6 17.9 30.1 36.0 12.5 22.4 15.9 14.7 22.0 27.3 23.4 49.0 35.6 34.0 15.3 22.4 43.0 36.3 39.6 12.7 23.2 26.6 7.1 48.6 22.0 7.8 30.8 15.0 33.6 41.8 46.1 25.4 25.3 16.9 14.3 42.2 17.2 19.1 16.8 22.7 30.0 28.3 27.5 14.3 24.1 13.7 35.7 22.9 42.4 34.4 28.2 19.0 53.9 22.5 56.5 53.4 16.2 60.5 22.5 59.7 62.8 21.7 22.0 85.5 75.3 41.8 74.4 28.8 13.1 48.2 76.2 11.1 13.6 12.5 10.4 8.7 10.5 12.3 12.0 13.0 11.7 11.4 16.9 37.9 41.7 101.1 51.2 49.5 23.1 30.1 15.3 40.9 27.8 27.0 15.5 13.5 45.8 32.5 27.6 20.9 6.0 77.0 26.3 17.6 13.4 468.3 38.9 25.8 31.4 19.8 26.5 55.1 10.2 13.0 35.8 24.5 45.9 55.1 27.9 40.7 46.1 11.2 35.3 54.1 30.0 34.6 43.6 23.7 209.1 42.0 35.4 10.6 58.1 44.9 38.3 79.3 63.3 85.7 10.8 19.0 42.9 48.7 31.4 29.2 25.3 38.3 22.5 39.5 36.2 26.1 161.4 61.3 33.7 27.6 4.1 118.9 25.2 21.7 35.6 RBM43 "C2orf38, FLJ45645" ENSG00000184898 "RNA binding motif protein 43" Q6ZSC3 2 151247940-151261863 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 20.4;HSkMC: 18.5" "Low region specificity" "Detected in all" HPA038204 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Nucleoplasm "HPA038204: AB_10669520" "unprognostic (3.50e-2)" "unprognostic (5.45e-2)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-1)" "unprognostic (1.12e-1)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" "unprognostic (9.72e-3)" "unprognostic (2.57e-2)" "unprognostic (3.43e-3)" "unprognostic (1.22e-2)" "unprognostic (3.07e-2)" "unprognostic (1.12e-2)" "unprognostic (9.94e-2)" 5.2 8.7 2.4 4.2 2.3 6.7 6.9 1.6 2.3 7.5 3.5 4.2 3.0 7.6 9.4 3.2 12.3 6.8 3.2 2.1 2.7 7.0 6.7 6.1 6.9 2.9 2.9 15.4 4.0 5.1 2.9 5.7 2.3 6.5 4.4 1.8 5.2 7.7 3.4 4.7 3.9 5.7 2.8 7.9 4.6 3.6 2.9 7.0 12.3 2.5 4.7 3.8 3.1 3.0 3.5 2.2 3.5 4.7 9.4 20.4 2.3 4.0 9.2 5.0 7.2 0.1 5.7 2.7 1.5 7.3 2.7 1.7 1.1 4.6 2.5 4.2 2.5 6.6 1.0 0.2 9.1 8.2 2.2 18.5 5.0 4.0 3.0 7.4 10.7 2.9 2.7 3.0 6.8 3.5 4.7 3.9 1.3 0.1 4.2 3.2 4.1 1.6 8.4 3.0 1.3 4.2 3.8 2.8 7.8 0.6 4.1 5.2 6.1 3.7 3.3 3.2 1.7 1.1 0.8 0.0 9.7 3.3 2.3 1.0 0.7 3.0 1.2 0.9 2.0 1.2 1.6 1.5 0.5 1.3 2.0 1.5 0.8 2.7 2.4 0.2 0.8 0.6 2.4 2.3 1.6 2.3 2.1 2.7 2.9 2.9 2.3 2.8 2.9 3.0 26.5 3.2 8.9 2.9 9.6 3.3 3.2 5.8 5.7 6.7 8.6 14.9 2.6 11.5 5.7 18.4 0.0 6.8 8.4 1.7 27.4 6.8 3.0 30.9 17.2 16.9 6.1 8.8 1.0 5.9 4.7 21.8 5.6 9.4 3.8 13.4 20.7 9.1 5.1 6.7 1.3 6.9 4.1 10.4 4.3 2.4 28.0 8.2 3.6 2.8 12.3 22.1 13.4 4.0 0.9 4.6 5.6 29.0 5.5 2.8 5.5 18.2 26.3 1.3 0.0 18.4 13.0 0.5 3.6 7.3 3.1 1.4 13.5 30.4 3.7 2.2 RBMS1 "C2orf12, DKFZp564H0764, HCC-4, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1" ENSG00000153250 "RNA binding motif single stranded interacting protein 1" P29558 2 160272151-160493807 "Predicted intracellular proteins" "DNA replication" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 398.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047943, HPA061791" Enhanced Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA047943: AB_2797235, HPA061791: AB_2684611" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (3.78e-2)" "unprognostic (1.38e-3)" "unprognostic (2.50e-1)" "unprognostic (6.81e-3)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.14e-1)" "unprognostic (7.16e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (1.33e-7)" "unprognostic (1.84e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (2.32e-1)" 58.2 22.6 8.7 43.3 13.3 35.8 34.5 9.7 11.9 36.6 17.2 38.9 12.8 51.7 12.6 28.9 31.6 34.1 41.0 7.2 10.7 36.5 22.3 47.7 28.3 13.8 12.3 44.1 10.2 50.4 16.0 83.8 15.0 24.0 15.8 6.8 19.2 28.6 16.4 29.4 20.5 56.9 10.9 40.7 20.1 10.4 13.4 26.1 23.0 23.8 22.0 57.0 31.6 10.2 50.5 18.2 63.9 8.4 90.2 155.6 77.1 62.7 89.1 42.4 43.8 50.9 36.9 0.4 76.3 106.6 20.0 30.0 31.1 46.0 69.2 40.9 23.2 18.9 44.2 41.0 82.3 30.8 1.1 187.9 35.6 73.7 32.8 56.7 67.5 15.1 1.2 23.0 103.2 39.4 28.8 31.2 39.3 8.3 40.1 21.6 55.7 25.5 64.9 61.1 8.3 21.7 39.1 22.9 60.2 78.8 11.7 47.9 81.7 75.3 47.7 69.7 57.5 12.2 0.7 21.2 60.7 46.2 49.2 4.0 20.5 26.2 8.6 12.0 29.5 0.9 14.9 13.3 13.7 1.9 24.1 10.9 44.4 13.7 6.9 7.6 2.7 11.0 8.7 13.3 9.7 11.9 7.2 10.7 13.8 12.3 15.0 10.9 13.4 10.2 102.8 112.2 97.8 12.1 37.3 91.1 110.0 59.1 55.2 3.0 44.7 43.2 62.3 18.6 48.1 69.9 0.0 99.1 83.9 0.4 25.4 24.5 59.2 39.8 141.4 126.0 0.0 38.3 132.7 47.3 112.6 161.8 36.7 42.0 20.3 40.8 162.8 29.1 126.3 1.7 136.1 0.5 22.4 123.4 80.2 15.5 88.9 103.8 55.2 153.6 81.2 20.8 93.7 116.1 19.7 96.4 1.3 98.9 23.3 107.0 0.3 36.4 54.1 1.4 78.9 113.6 185.9 6.7 14.5 47.3 82.5 398.3 113.0 53.4 0.5 175.5 RBPMS HERMES ENSG00000157110 "RNA binding protein, mRNA processing factor" Q93062 8 30384511-30572256 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 324.1;RPTEC TERT1: 232.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056999 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA056999: AB_2683306" "unprognostic (1.65e-1)" "unprognostic (7.81e-2)" "unprognostic (1.53e-1)" "unprognostic (2.23e-3)" "unprognostic (8.66e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-2)" "unprognostic (3.47e-3)" "unprognostic (4.63e-2)" "unprognostic (2.32e-1)" "unprognostic (4.67e-2)" "unprognostic (2.88e-2)" "unprognostic (1.76e-2)" "unprognostic (4.76e-2)" "unprognostic (2.52e-1)" "unprognostic (4.91e-2)" "unprognostic (2.16e-3)" 238.3 96.7 22.3 43.8 28.0 1.4 194.8 20.2 24.1 196.9 26.7 350.6 25.2 200.7 90.0 99.9 200.5 95.4 174.7 17.3 25.2 218.7 108.9 119.6 23.3 23.1 27.6 190.0 68.8 68.6 33.0 105.0 28.7 182.6 46.6 10.4 92.1 193.7 31.2 56.6 107.7 171.9 18.7 56.7 159.8 45.4 33.2 23.5 140.7 31.6 20.0 323.4 134.0 18.9 0.7 54.5 58.5 0.4 324.1 96.4 145.8 74.8 101.8 90.2 74.6 76.2 31.2 0.5 39.3 96.7 82.5 29.9 68.0 54.4 107.9 0.1 14.6 1.8 24.7 80.5 139.4 0.5 12.0 112.8 13.8 86.7 11.5 100.8 52.8 2.5 0.5 0.4 44.6 32.6 0.3 1.2 150.9 62.3 34.6 3.5 16.2 4.7 232.2 88.9 1.1 11.6 7.7 55.2 37.7 192.3 11.7 0.0 48.8 44.3 4.2 77.3 12.8 0.1 0.2 0.4 72.8 0.2 20.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 22.3 28.0 20.2 24.1 17.3 25.2 23.1 27.6 28.7 18.7 33.2 18.9 104.0 54.5 98.9 36.6 4.5 9.3 61.8 22.7 14.2 6.7 45.8 64.3 114.4 75.8 48.5 141.6 2.1 108.7 4.1 1.8 113.5 100.0 104.7 31.2 86.3 69.7 1.8 5.0 6.4 94.8 184.8 66.7 18.8 48.2 10.1 18.0 44.3 55.2 39.9 0.0 5.2 0.1 20.3 1.9 10.2 31.5 171.2 4.3 14.2 71.2 2.1 1.0 1.0 2.0 1.6 67.0 0.0 180.2 0.5 101.5 2.0 242.2 30.9 5.7 111.7 6.6 149.9 35.3 22.0 27.8 8.0 41.2 4.4 28.1 1.0 151.7 RCN1 "FLJ37041, PIG20, Rcal, RCN" ENSG00000049449 "Reticulocalbin 1" Q15293 11 32091074-32105722 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "epididymis: 660.2" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 288.2;Muller glia cells: 327.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA038474, HPA062104" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 9400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA038474: AB_10672595, HPA062104: AB_2684683" "unprognostic (1.65e-1)" "unprognostic (7.69e-3)" "unprognostic (1.24e-1)" "unprognostic (2.03e-2)" "unprognostic (7.20e-3)" "unprognostic (1.70e-2)" "unprognostic (6.92e-3)" "prognostic unfavorable (7.13e-6)" "unprognostic (8.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.12e-1)" "unprognostic (9.32e-2)" "prognostic unfavorable (2.70e-13)" "unprognostic (1.78e-2)" "unprognostic (2.04e-1)" "unprognostic (1.14e-1)" "unprognostic (6.93e-3)" 81.8 54.4 26.7 58.3 39.6 8.1 64.6 24.0 28.2 73.9 37.2 54.7 43.4 79.7 660.2 25.7 69.5 50.1 46.0 26.4 37.2 39.2 100.7 50.6 29.2 29.9 27.6 83.6 21.9 62.2 67.3 129.0 29.0 85.6 53.7 48.7 89.9 82.5 32.7 26.8 41.5 79.5 31.8 35.9 40.7 22.5 36.7 19.0 63.4 28.8 23.1 113.1 41.1 31.3 130.0 143.7 335.9 217.4 720.2 548.1 340.4 425.5 501.5 286.6 515.6 123.6 157.2 0.4 293.3 718.4 380.4 157.6 118.0 135.2 450.2 63.9 231.9 28.2 104.7 58.4 519.7 21.7 42.0 780.1 154.8 197.1 215.4 333.7 647.7 60.6 17.4 25.8 342.1 116.0 61.4 50.2 137.2 2.7 143.9 45.1 393.5 39.2 270.1 355.8 82.1 42.6 117.1 26.2 333.1 227.2 171.0 77.5 350.8 417.0 215.8 338.5 364.6 1.0 0.9 1.7 514.2 28.3 224.9 0.3 13.6 0.5 14.9 16.2 11.8 6.2 6.9 12.3 15.2 4.8 5.1 9.5 0.6 10.9 10.3 8.2 2.7 9.3 26.7 39.6 24.0 28.2 26.4 37.2 29.9 27.6 29.0 31.8 36.7 31.3 131.3 54.5 34.8 9.8 11.8 41.6 80.8 78.2 34.1 40.4 47.9 37.5 9.0 42.9 55.1 47.8 12.5 172.6 10.5 14.3 7.9 143.4 210.4 60.7 154.9 112.1 53.2 16.4 8.0 45.7 288.2 152.1 23.0 110.2 12.7 100.3 85.3 61.7 44.2 15.2 5.9 80.9 38.7 17.8 33.9 173.8 80.5 19.9 32.0 8.4 50.3 327.4 19.6 16.6 1.3 39.7 30.8 73.0 38.6 184.9 6.7 14.1 30.4 17.0 26.3 80.8 91.7 17.0 7.2 33.2 28.3 217.0 13.6 55.8 75.3 99.8 RCN3 RLP49 ENSG00000142552 "Reticulocalbin 3" Q96D15 19 49528003-49546962 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 54.7;Fibroblasts: 105.1;Leydig cells: 38.2;Peritubular cells: 44.8;Smooth muscle cells: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 6.8" "Group enriched" "Detected in many" 9 "granulocytes: 2.5;NK-cells: 1.8;T-cells: 6.8" "Cell line enhanced" "Detected in many" "AN3-CA: 166.6;ASC diff: 283.3;ASC TERT1: 175.4;BJ: 353.8;BJ hTERT+ SV40 Large T+ RasG12V: 179.6;fHDF/TERT166: 304.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043134, HPA050402" Uncertain Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" No No 1600000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA043134: AB_2678332, HPA050402: AB_2681114" "unprognostic (7.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.77e-3)" "unprognostic (8.87e-2)" "unprognostic (3.36e-3)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (1.16e-1)" "unprognostic (7.47e-2)" "unprognostic (9.75e-2)" "unprognostic (2.85e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (5.80e-12)" "unprognostic (5.26e-2)" "unprognostic (3.90e-2)" "unprognostic (1.56e-2)" "unprognostic (4.20e-3)" 67.9 35.3 15.8 33.6 17.2 6.8 48.2 15.5 24.1 78.8 23.5 43.5 39.9 47.4 4.4 11.4 41.4 25.2 56.7 16.0 19.1 41.2 62.3 40.8 8.7 17.4 17.0 50.0 16.4 3.9 20.7 31.1 19.0 32.4 11.4 1.4 19.1 12.1 11.7 25.3 43.2 25.7 16.8 65.9 23.4 17.2 24.5 4.0 26.4 7.5 4.1 43.2 46.3 18.8 3.2 4.3 2.7 166.6 283.3 175.4 1.9 353.8 86.5 122.0 179.6 4.2 1.3 1.3 19.5 304.0 1.3 0.3 6.8 0.5 49.2 0.1 2.5 19.5 1.5 9.1 105.7 0.1 43.0 119.5 0.2 93.2 0.4 3.2 43.8 2.3 8.7 1.0 87.8 2.9 0.1 2.0 1.4 8.8 24.5 0.5 3.9 4.0 1.4 0.0 1.7 10.5 0.3 1.1 0.3 2.8 1.3 11.5 121.4 1.7 52.4 135.3 0.1 14.9 44.5 2.6 7.9 9.6 13.4 0.0 0.2 1.6 0.7 0.0 0.7 0.4 1.7 0.6 0.4 0.2 6.8 2.3 2.5 1.8 0.3 0.2 1.6 1.1 15.8 17.2 15.5 24.1 16.0 19.1 17.4 17.0 19.0 16.8 24.5 18.8 12.0 0.0 6.1 4.6 2.8 18.6 0.6 2.9 3.4 0.8 1.7 3.3 2.1 1.5 0.8 1.8 0.0 2.5 1.4 10.5 1.9 1.6 2.2 1.5 54.7 10.6 1.2 0.0 1.0 0.5 5.0 105.1 6.6 1.6 1.3 7.0 27.1 3.7 22.6 1.7 1.1 7.6 0.0 11.4 23.2 3.0 38.2 11.9 10.6 10.3 3.1 0.6 0.0 1.5 0.8 1.5 7.9 44.8 4.8 0.9 13.1 0.6 0.9 0.8 13.1 37.5 66.5 6.5 6.8 2.8 13.9 6.2 2.2 17.2 8.0 0.4 RDH5 "HSD17B9, RDH1, SDR9C5" ENSG00000135437 "Retinol dehydrogenase 5" Q92781 12 55720367-55724705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Steroid metabolism, Vision" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 94.5;liver: 58.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Proximal enterocytes: 49.9;Rod photoreceptor cells: 62.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 28.5;ASC TERT1: 24.3;hTEC/SVTERT24-B: 15.3;hTERT-RPE1: 24.5;LHCN-M2: 15.4;U-87 MG: 26.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063345 Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA063345: AB_2684992" "unprognostic (1.04e-2)" "unprognostic (6.45e-2)" "unprognostic (1.80e-1)" "unprognostic (2.67e-1)" "unprognostic (3.66e-2)" "unprognostic (1.48e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.35e-2)" "unprognostic (4.04e-2)" "unprognostic (4.05e-1)" "unprognostic (1.26e-3)" "unprognostic (7.63e-2)" "unprognostic (8.79e-2)" "unprognostic (3.46e-2)" "unprognostic (2.12e-3)" "unprognostic (3.27e-2)" 94.5 1.8 2.2 4.1 2.5 1.0 34.2 2.2 2.6 2.5 3.5 13.6 18.5 4.2 7.8 3.1 4.6 4.2 9.2 2.0 2.2 9.0 58.9 1.9 1.8 2.7 2.5 2.1 3.5 0.3 1.7 0.6 2.4 4.4 4.4 3.2 3.3 2.2 6.1 2.7 15.5 19.5 2.5 2.2 5.9 2.4 2.8 0.9 2.7 7.6 0.7 5.5 2.2 3.4 0.7 1.4 0.8 0.5 28.5 24.3 0.6 3.8 4.2 0.7 1.4 0.5 7.9 1.0 0.7 2.1 0.2 0.3 0.3 0.1 0.6 1.0 1.3 0.1 2.0 2.1 0.8 0.1 0.3 10.5 1.0 15.3 0.1 24.5 0.3 0.5 0.2 1.3 15.4 0.7 0.4 0.2 0.3 3.7 2.3 0.6 0.4 0.5 0.2 0.8 0.2 1.1 0.2 0.5 3.4 0.2 0.7 0.6 0.5 1.5 1.5 1.1 0.9 1.1 0.5 0.2 26.7 0.4 0.3 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.2 0.5 0.2 0.0 0.2 0.0 0.2 0.3 0.2 0.5 0.0 0.0 2.2 2.5 2.2 2.6 2.0 2.2 2.7 2.5 2.4 2.5 2.8 3.4 2.5 9.6 2.2 0.0 4.6 1.9 4.5 3.9 0.6 24.3 2.7 5.0 3.9 10.0 2.4 1.8 62.6 2.2 5.3 23.5 1.9 2.1 0.8 1.8 2.9 3.7 11.5 0.0 0.0 2.6 1.2 3.9 11.2 1.5 0.0 4.9 3.6 18.4 0.6 16.8 0.0 10.3 0.0 4.5 7.9 2.3 13.4 2.3 5.4 0.0 4.7 8.2 12.3 0.0 0.0 3.6 18.6 6.8 0.7 3.2 49.9 13.0 4.7 62.9 13.1 14.0 9.3 3.9 6.4 0.8 1.7 1.5 4.8 5.3 15.9 3.1 RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 63.1;Inhibitory neurons: 71.1;Oligodendrocyte precursor cells: 80.4;Oligodendrocytes: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 199.5;ASC TERT1: 158.5;BJ: 65.1;BJ hTERT+: 93.0;fHDF/TERT166: 57.8;HSkMC: 71.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" 14.7 7.4 3.0 4.6 3.3 1.2 13.7 3.4 4.3 15.2 2.7 6.8 3.7 14.4 6.1 11.7 8.0 13.7 8.5 4.6 3.3 5.7 5.8 12.7 5.8 3.4 3.1 14.3 3.2 3.7 3.1 11.3 3.5 8.3 6.3 4.7 4.7 7.3 3.7 7.6 5.1 14.7 3.1 7.3 5.7 3.2 3.4 6.6 6.2 16.0 4.4 12.1 7.5 4.0 1.4 2.4 8.0 4.4 199.5 158.5 0.1 65.1 93.0 4.7 11.0 0.0 0.0 2.5 6.0 57.8 3.7 0.4 1.8 1.2 6.4 4.1 3.7 2.6 2.8 0.2 16.2 0.3 11.1 71.3 1.6 7.1 2.7 18.4 14.6 4.8 0.0 2.1 12.2 0.3 6.6 1.0 2.7 0.0 2.0 6.9 6.2 0.0 3.2 0.2 0.7 4.5 1.5 0.8 2.7 8.3 0.0 8.9 44.4 9.0 3.3 5.9 3.6 2.9 3.4 2.7 5.5 8.7 5.8 1.0 2.6 0.7 3.9 2.8 4.4 1.2 5.2 4.2 2.9 2.7 6.3 4.6 0.3 3.0 4.8 1.6 2.6 2.3 3.0 3.3 3.4 4.3 4.6 3.3 3.4 3.1 3.5 3.1 3.4 4.0 12.8 3.2 5.4 40.1 11.7 7.1 4.0 5.0 4.6 12.5 4.2 5.6 3.6 1.5 2.5 3.7 14.6 0.9 9.3 0.2 0.0 6.6 38.3 0.9 11.6 19.6 6.1 5.7 63.1 1.5 7.7 53.4 3.6 0.6 9.5 9.2 25.4 1.1 15.6 8.4 71.1 1.3 4.1 15.7 15.9 35.5 18.6 8.3 3.6 41.2 8.8 14.3 2.1 80.4 119.8 1.3 0.4 17.7 5.9 4.3 0.3 1.6 4.1 7.8 0.0 14.2 15.3 41.2 27.4 1.3 7.5 0.8 10.2 7.8 0.8 1.2 RETSAT FLJ20296 ENSG00000042445 "Retinol saturase" Q6NUM9 2 85341955-85354531 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 247.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 264.9;Proximal enterocytes: 249.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 197.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007961, HPA046513" Uncertain Uncertain Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Nucleoli "HPA007961: AB_1079802, HPA046513: AB_2679680" "unprognostic (6.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.29e-1)" "unprognostic (5.84e-3)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "prognostic favorable (4.23e-4)" "unprognostic (1.89e-1)" "unprognostic (2.16e-1)" "unprognostic (3.59e-2)" "unprognostic (1.77e-2)" "unprognostic (1.59e-1)" "prognostic favorable (1.95e-10)" "unprognostic (2.73e-2)" "unprognostic (5.34e-1)" "unprognostic (8.24e-3)" "unprognostic (9.90e-2)" 247.0 52.3 16.5 17.6 20.9 3.8 63.9 19.8 15.8 18.9 27.3 89.6 167.0 16.0 38.4 36.9 15.7 32.0 20.3 14.9 20.0 54.9 115.9 24.6 11.7 21.0 20.0 17.0 37.5 36.9 7.2 11.6 20.0 32.5 73.5 9.5 27.8 23.6 68.3 48.8 142.4 22.0 19.2 11.7 60.9 14.6 19.9 12.2 47.4 55.1 19.9 19.0 23.7 23.7 52.7 30.1 16.8 40.0 197.8 37.0 22.1 37.8 46.5 22.5 31.5 20.9 36.2 18.5 30.3 29.6 17.9 42.6 22.9 65.6 21.6 22.8 15.9 9.0 23.5 50.6 47.6 17.9 19.3 48.6 87.2 28.7 38.1 51.4 37.6 15.4 9.7 43.1 42.0 11.0 12.5 9.0 5.6 52.6 36.2 8.1 33.7 23.9 39.1 30.1 8.3 13.8 31.4 59.9 101.8 11.2 28.2 2.9 30.0 25.3 13.8 23.5 19.9 23.0 22.9 7.2 30.9 20.5 17.6 0.0 3.8 1.8 4.8 4.0 6.2 2.6 3.5 6.0 4.0 1.5 2.5 2.5 3.7 5.1 8.7 2.7 4.2 3.4 16.5 20.9 19.8 15.8 14.9 20.0 21.0 20.0 20.0 19.2 19.9 23.7 7.3 28.9 29.6 5.9 4.5 11.3 10.8 18.6 12.5 3.7 13.0 7.9 21.7 21.5 15.5 12.9 18.8 10.9 4.3 264.9 0.0 23.7 27.6 9.7 6.8 9.7 10.8 2.5 5.7 36.1 6.5 9.0 56.1 16.6 10.8 5.5 7.5 54.7 9.9 11.8 4.5 45.0 8.2 10.4 8.6 60.0 14.6 7.4 30.2 7.5 8.3 8.3 10.3 6.6 12.1 32.7 79.2 12.4 10.3 11.8 249.9 17.8 11.9 4.9 0.0 7.7 8.8 2.9 3.1 24.9 14.9 8.5 7.7 9.9 56.6 9.8 RFTN2 "C2orf11, FLJ30574, Raftlin-2" ENSG00000162944 "Raftlin family member 2" Q52LD8 2 197568224-197676045 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 70.9" "Group enriched" "Detected in many" 7 "Astrocytes: 152.8;Early spermatids: 125.0;Late spermatids: 351.7;Oligodendrocyte precursor cells: 198.5;Oligodendrocytes: 320.6" "Cancer enriched" "Detected in many" 5 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.8;ASC diff: 15.5;ASC TERT1: 8.7;HSkMC: 10.7;TIME: 6.4;WM-115: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035232, HPA043190" Approved Approved "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA035232: AB_10601495, HPA043190: " "unprognostic (1.15e-1)" "unprognostic (3.52e-1)" "unprognostic (2.07e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.89e-2)" "unprognostic (1.81e-1)" "unprognostic (3.09e-2)" "unprognostic (2.16e-2)" "unprognostic (6.04e-2)" "unprognostic (1.39e-1)" "unprognostic (1.05e-1)" "unprognostic (8.44e-3)" "unprognostic (2.56e-2)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (6.77e-2)" 10.8 4.7 30.0 1.9 48.9 0.3 3.2 39.2 32.6 4.4 3.7 1.8 0.7 4.6 1.2 2.5 2.2 4.4 3.4 28.3 29.4 2.0 1.0 2.4 2.5 42.5 36.6 9.9 1.9 0.6 0.7 6.2 49.5 1.7 1.9 4.3 3.3 1.6 1.5 2.3 1.3 3.3 40.2 1.9 1.5 3.0 33.7 0.8 1.9 5.8 1.5 2.7 2.4 70.9 0.2 0.0 19.8 0.4 15.5 8.7 0.7 0.2 1.3 0.0 1.1 0.3 0.4 0.4 0.5 1.8 0.4 0.6 0.0 0.0 0.0 0.8 0.1 0.1 1.0 0.0 2.2 0.3 0.3 10.7 0.4 0.1 0.0 0.1 2.3 0.6 0.0 0.2 0.4 0.9 0.1 0.1 0.8 0.8 0.6 0.1 0.5 0.2 0.0 0.2 0.5 0.2 0.0 0.0 3.0 3.4 0.1 0.0 6.4 1.7 0.3 0.1 0.3 0.5 1.1 0.2 1.6 0.0 9.6 0.2 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.1 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.1 0.1 0.0 30.0 48.9 39.2 32.6 28.3 29.4 42.5 36.6 49.5 40.2 33.7 70.9 14.8 0.0 0.6 152.8 0.2 2.4 0.2 0.1 0.0 1.3 1.3 1.4 2.2 2.8 0.1 0.0 0.0 0.2 0.5 0.1 0.0 1.0 125.0 0.9 9.7 13.0 0.0 0.0 1.2 0.0 0.1 16.3 0.0 0.4 0.0 8.6 19.6 0.3 0.4 3.3 1.5 0.0 0.0 0.6 3.3 351.7 15.8 0.7 16.0 32.8 0.0 23.5 0.0 198.5 320.6 0.1 0.0 22.2 1.6 0.3 0.0 0.1 0.2 1.5 6.6 16.2 8.3 4.5 2.8 0.5 2.3 0.0 0.6 3.3 0.0 0.1 RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Excitatory neurons: 176.1;Inhibitory neurons: 141.8;Kupffer cells: 109.1;Oligodendrocytes: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;HSkMC: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: AB_1856215" "unprognostic (3.08e-1)" "unprognostic (5.25e-3)" "unprognostic (8.73e-2)" "unprognostic (1.24e-2)" "unprognostic (2.34e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.49e-5)" "prognostic favorable (4.32e-4)" "unprognostic (1.12e-1)" "unprognostic (6.34e-2)" "unprognostic (5.77e-3)" "unprognostic (4.59e-2)" "unprognostic (2.63e-3)" "unprognostic (4.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.88e-2)" 24.7 16.8 22.7 19.9 25.3 1.6 17.1 17.3 27.0 18.6 21.5 11.3 8.7 18.0 6.3 10.6 15.2 22.5 17.0 27.1 21.7 28.6 16.2 20.9 22.9 23.7 20.7 19.2 6.8 8.9 9.5 16.1 17.4 13.2 12.8 15.7 7.7 11.6 2.7 8.9 10.6 22.2 21.1 45.4 6.9 14.7 23.9 8.7 9.1 7.7 10.1 18.7 8.9 28.5 0.3 1.5 26.3 4.0 35.0 16.1 26.7 12.4 20.6 5.5 6.8 12.2 0.7 0.3 11.3 8.8 4.3 0.6 1.8 3.1 5.4 0.4 1.9 0.2 2.6 12.6 9.3 0.4 1.5 54.9 0.7 14.0 3.3 26.2 20.8 2.7 0.0 19.6 11.8 0.1 2.9 0.2 9.6 0.9 0.7 23.7 1.7 24.3 1.5 7.5 3.3 7.9 3.9 4.2 2.1 8.5 0.2 0.3 15.3 7.9 3.1 24.7 6.8 2.0 0.5 0.1 8.3 0.3 22.2 0.0 0.8 0.0 0.0 2.1 0.1 0.0 0.3 0.0 0.9 0.0 0.4 0.2 0.0 0.0 0.8 0.0 0.2 0.5 22.7 25.3 17.3 27.0 27.1 21.7 23.7 20.7 17.4 21.1 23.9 28.5 9.4 9.6 12.3 133.5 1.6 8.2 2.2 2.5 5.2 5.1 6.7 4.6 8.7 5.7 9.0 5.5 0.0 5.1 0.6 2.6 5.9 4.0 13.8 7.9 23.2 19.7 0.0 0.4 176.1 0.9 2.6 22.0 3.6 24.1 3.8 11.0 41.4 2.6 43.3 8.4 141.8 0.8 4.1 109.1 50.4 17.6 13.1 43.7 5.4 76.8 1.7 23.0 0.0 38.7 184.3 1.0 0.1 20.7 0.1 3.5 2.8 30.1 14.2 2.0 26.3 1.2 9.7 4.0 2.5 5.8 4.7 5.2 2.2 13.1 0.6 2.9 RHOQ "ARHQ, RASL7A, TC10" ENSG00000119729 "Ras homolog family member Q" P17081 2 46541806-46584688 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 189.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.5;classical monocyte: 2.5;eosinophil: 4.2;intermediate monocyte: 2.7;memory B-cell: 1.7;myeloid DC: 1.6;naive B-cell: 2.4;neutrophil: 4.8;non-classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 164.0;ASC TERT1: 132.0;SK-MEL-30: 150.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044938 Approved Vesicles,Cytosol No No "Cluster 24: B-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "HPA044938: AB_2679149" "unprognostic (1.24e-1)" "unprognostic (1.30e-2)" "unprognostic (5.82e-2)" "unprognostic (2.07e-2)" "unprognostic (3.61e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.60e-5)" "unprognostic (2.01e-2)" "unprognostic (9.24e-2)" "unprognostic (2.11e-2)" "unprognostic (1.97e-1)" "unprognostic (5.43e-2)" "unprognostic (3.88e-3)" "unprognostic (1.39e-2)" "unprognostic (1.87e-1)" "unprognostic (7.68e-2)" "unprognostic (3.52e-2)" 96.9 35.7 34.8 30.1 40.1 12.4 64.8 38.9 41.4 59.6 43.9 67.0 11.0 53.2 67.7 18.9 59.3 26.7 196.8 34.3 44.7 44.3 22.6 56.0 23.8 40.9 44.2 40.8 28.6 50.4 29.5 28.6 38.9 50.6 13.5 27.7 32.7 36.5 162.4 28.1 35.3 38.4 39.2 42.7 32.8 10.1 36.8 9.9 39.1 181.3 19.1 62.8 44.7 43.5 12.3 12.4 21.0 28.6 164.0 132.0 3.7 32.8 84.1 16.2 24.4 6.2 4.1 28.7 34.0 58.5 52.4 5.8 20.6 9.8 29.3 10.2 15.3 8.2 9.8 20.9 81.8 8.8 10.7 118.1 17.3 20.1 22.5 39.0 19.3 3.1 12.1 44.0 35.2 8.1 6.9 17.9 20.8 8.9 14.4 5.3 34.5 10.1 23.1 22.4 15.3 50.3 11.6 16.4 150.8 32.9 9.0 20.7 13.2 50.1 44.8 49.3 14.1 48.5 17.7 28.4 73.6 22.1 18.4 1.5 2.5 4.2 0.4 2.7 0.3 1.7 0.2 0.4 1.6 2.4 0.0 0.3 4.8 0.3 1.9 0.6 0.3 0.7 34.8 40.1 38.9 41.4 34.3 44.7 40.9 44.2 38.9 39.2 36.8 43.5 27.9 57.7 22.4 65.3 38.1 22.4 31.0 18.1 11.4 21.1 30.4 22.4 189.2 14.3 22.1 20.2 10.4 14.6 32.2 1.0 17.6 21.4 30.8 22.1 90.2 23.4 6.0 2.1 12.8 32.0 3.6 82.8 4.1 24.6 12.0 12.1 17.5 12.2 44.5 121.1 27.7 5.5 8.2 90.9 77.8 11.4 35.4 90.7 42.7 68.4 55.1 52.9 15.5 52.3 41.5 22.4 0.3 42.5 42.0 41.2 0.2 30.1 18.8 24.2 46.0 54.2 82.3 2.3 4.5 6.8 19.7 25.9 17.0 10.9 1.9 31.9 RMDN2 "FAM82A, FAM82A1, FLJ32954, RMD2" ENSG00000115841 "Regulator of microtubule dynamics 2" Q96LZ7 2 37923187-38067142 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 42.5" "Group enriched" "Detected in many" 4 "Early spermatids: 270.4;Late spermatids: 163.5;Theca cells: 77.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034705, HPA034706" Enhanced Supported "Golgi apparatus,Mitotic spindle,Cytosol" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Mitotic spindle, Cytosol" "Golgi apparatus" "HPA034705: AB_2674292, HPA034706: AB_10696362" "unprognostic (1.34e-1)" "unprognostic (2.61e-1)" "unprognostic (4.03e-2)" "unprognostic (1.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.76e-1)" "unprognostic (3.06e-2)" "prognostic favorable (2.63e-4)" "unprognostic (7.85e-2)" "unprognostic (9.96e-2)" "unprognostic (7.50e-2)" "unprognostic (1.94e-1)" "unprognostic (2.88e-2)" "unprognostic (5.08e-3)" "unprognostic (1.20e-1)" "unprognostic (4.34e-3)" "unprognostic (3.34e-1)" 4.6 42.5 3.8 4.1 3.5 3.4 5.3 4.8 4.5 7.7 2.9 12.4 8.4 5.1 9.2 3.4 3.9 6.2 4.4 4.1 2.6 7.8 29.2 11.3 4.6 3.9 2.6 2.8 4.1 3.2 3.0 3.9 2.6 7.2 10.6 4.2 3.7 12.8 5.1 2.9 13.9 5.8 3.0 20.0 4.4 21.7 3.6 5.9 5.4 3.2 2.9 4.3 3.5 3.7 3.3 4.7 2.6 1.8 10.4 11.4 1.5 7.0 9.3 3.6 3.2 1.1 10.9 2.2 2.8 9.9 2.2 3.5 0.8 5.1 4.9 5.0 3.0 3.6 1.6 3.1 5.3 0.0 3.8 16.2 4.6 4.5 0.7 5.4 2.0 1.8 4.4 2.1 6.8 1.3 0.9 4.5 5.1 6.5 3.8 0.0 0.8 0.6 9.0 2.7 2.1 7.5 5.7 0.7 7.3 2.2 1.1 5.9 3.8 4.4 5.1 2.5 2.6 3.8 7.7 4.6 5.4 1.1 4.6 0.0 2.8 0.7 2.0 4.6 3.1 4.1 1.0 1.3 1.8 2.3 1.0 2.2 2.7 3.7 3.5 3.4 0.1 1.4 3.8 3.5 4.8 4.5 4.1 2.6 3.9 2.6 2.6 3.0 3.6 3.7 3.4 28.9 29.6 25.1 6.5 2.4 6.8 16.3 8.6 3.5 1.9 4.2 5.3 11.5 20.0 5.5 2.1 2.1 6.0 20.9 7.9 5.4 270.4 3.7 11.8 4.6 4.8 3.0 33.8 3.8 1.0 9.2 2.6 3.1 15.8 13.1 5.3 15.5 4.7 5.0 24.5 11.4 6.1 6.3 1.7 163.5 9.3 4.8 5.4 19.7 4.4 4.7 6.2 39.2 7.1 2.5 6.1 6.0 1.8 2.2 29.6 6.7 10.2 2.6 6.6 6.4 5.1 9.4 4.8 1.7 2.4 0.8 3.9 77.6 15.2 2.3 ROR1 NTRKR1 ENSG00000185483 "Receptor tyrosine kinase like orphan receptor 1" Q01973 1 63774017-64181498 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Receptor, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 26.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Astrocytes: 81.0;Inhibitory neurons: 69.7;Microglial cells: 36.5;Oligodendrocytes: 109.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 40.5;ASC TERT1: 50.3;CACO-2: 36.8;HHSteC: 38.3;HSkMC: 41.6;NTERA-2: 43.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 7700000 "Cluster 40: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (5.15e-2)" "unprognostic (1.19e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-2)" "unprognostic (6.24e-2)" "unprognostic (1.61e-1)" "unprognostic (7.11e-3)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "unprognostic (3.84e-1)" "unprognostic (3.20e-2)" "unprognostic (2.02e-2)" "unprognostic (3.64e-3)" "unprognostic (1.48e-2)" "unprognostic (1.52e-1)" "unprognostic (5.87e-2)" "unprognostic (5.15e-2)" 4.4 1.1 0.6 2.2 1.4 0.4 3.7 3.0 0.8 7.5 4.6 4.5 2.2 7.1 1.4 5.2 2.5 5.2 7.5 0.7 0.6 2.3 0.5 7.0 1.2 0.7 0.9 8.3 5.5 26.9 0.5 3.1 0.5 5.4 4.0 1.5 1.2 6.4 2.3 2.3 1.7 7.7 0.3 3.2 6.4 1.5 1.2 2.5 1.4 1.6 1.1 4.2 2.3 1.1 15.5 12.2 5.9 0.8 40.5 50.3 4.0 2.9 8.3 1.6 4.3 36.8 4.9 0.3 6.6 7.2 2.9 3.2 0.1 2.9 1.1 0.0 3.7 0.0 1.6 0.5 38.3 0.0 0.0 41.6 10.9 21.7 25.2 8.4 0.7 0.5 0.0 0.3 11.0 0.2 0.2 0.1 43.0 11.3 6.1 0.2 0.2 9.8 8.7 0.3 3.4 13.6 0.8 0.2 6.4 19.9 0.1 0.0 8.4 3.3 5.7 23.0 6.2 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.6 1.4 3.0 0.8 0.7 0.6 0.7 0.9 0.5 0.3 1.2 1.1 1.1 51.3 10.5 81.0 1.8 3.8 2.2 0.5 29.0 4.7 3.0 2.0 11.4 1.5 1.3 1.8 0.0 0.2 0.1 1.3 0.0 5.6 9.6 1.2 9.2 1.8 21.5 0.0 11.6 15.2 1.0 14.5 16.8 1.9 0.0 1.1 0.7 0.0 7.6 0.0 69.7 2.2 2.0 0.6 4.9 8.1 27.7 0.5 3.6 36.5 0.0 5.3 0.0 3.5 109.9 15.3 0.8 14.7 0.1 1.4 0.0 3.4 0.8 0.3 6.6 6.8 8.5 1.4 1.8 11.5 4.5 0.3 0.2 0.3 3.3 0.8 RPS6KA2 "HU-2, RSK3" ENSG00000071242 "Ribosomal protein S6 kinase A2" Q15349 6 166409364-166906451 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 399.6;Excitatory neurons: 204.1;Horizontal cells: 287.7;Inhibitory neurons: 552.3;Oligodendrocyte precursor cells: 244.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 26.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "eosinophil: 22.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 22.4" "Cell line enhanced" "Detected in many" "ASC diff: 214.5;ASC TERT1: 156.1;HHSteC: 158.5;HSkMC: 141.4;hTERT-HME1: 173.0;hTERT-RPE1: 316.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026243, HPA045061, HPA054237, CAB069428" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB026243: , CAB069428: AB_1622639, HPA045061: AB_2679203, HPA054237: AB_2682425" "unprognostic (8.71e-2)" "unprognostic (3.14e-3)" "unprognostic (7.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.80e-1)" "unprognostic (2.45e-1)" "unprognostic (6.44e-3)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (8.63e-5)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "prognostic favorable (2.86e-5)" "unprognostic (3.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (2.01e-1)" 34.2 9.0 40.3 8.0 41.0 10.5 27.8 35.0 35.2 18.1 8.6 16.6 6.1 26.0 7.1 20.1 18.7 18.2 61.8 37.8 42.1 13.6 6.6 45.1 7.5 48.3 41.7 29.2 19.4 49.6 27.2 17.9 42.0 14.9 10.3 28.9 14.7 14.2 24.1 16.4 16.5 22.7 35.3 26.0 21.4 7.7 47.3 5.9 36.3 30.5 7.3 24.5 14.9 49.3 9.1 0.0 17.9 26.0 214.5 156.1 0.4 19.3 37.4 10.6 14.6 0.0 5.8 1.1 6.2 68.2 8.4 8.2 9.4 41.8 9.4 4.2 2.3 0.1 40.2 0.4 158.5 0.6 7.2 141.4 29.4 56.6 173.0 316.2 58.0 19.2 0.2 0.2 43.6 1.9 0.8 2.1 4.5 9.1 10.5 3.0 9.2 27.3 11.1 10.1 9.8 68.8 6.7 17.9 24.8 4.4 0.5 14.3 21.7 37.3 3.7 103.8 5.6 5.2 8.4 2.6 24.8 1.2 36.0 0.2 0.6 22.4 0.6 0.8 0.3 0.3 0.6 0.3 0.8 0.5 0.7 0.3 0.5 4.4 2.2 4.7 0.5 0.4 40.3 41.0 35.0 35.2 37.8 42.1 48.3 41.7 42.0 35.3 47.3 49.3 60.9 22.4 46.2 399.6 2.7 4.7 5.4 4.6 3.4 37.1 7.1 5.0 60.0 15.7 11.6 36.8 8.4 0.2 8.0 1.9 11.7 15.2 14.8 20.6 4.6 58.2 5.4 0.0 204.1 24.0 0.3 16.3 16.8 20.3 2.5 10.5 45.3 11.9 7.2 287.7 552.3 5.3 2.0 6.0 6.7 69.3 5.3 8.0 19.6 144.3 3.5 10.1 1.0 244.8 97.7 26.8 1.7 4.5 2.4 9.9 0.3 7.0 9.4 17.1 13.1 10.0 14.5 3.5 2.3 1.2 3.4 0.3 2.0 9.5 1.4 6.6 RRAGA "FIP-1, RAGA" ENSG00000155876 "Ras related GTP binding A" Q7L523 9 19049427-19051025 "Predicted intracellular proteins" "Apoptosis, Host-virus interaction" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003734 Supported Approved "Golgi apparatus,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "HPA003734: AB_1079851" "unprognostic (6.30e-2)" "unprognostic (4.65e-1)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (7.43e-4)" "unprognostic (6.74e-2)" "unprognostic (2.17e-2)" "unprognostic (2.11e-1)" "unprognostic (2.91e-1)" "unprognostic (2.20e-3)" "unprognostic (3.13e-1)" "unprognostic (2.65e-1)" "unprognostic (1.74e-2)" "unprognostic (4.88e-2)" "unprognostic (2.10e-3)" "unprognostic (1.05e-1)" 79.3 73.7 73.6 39.6 75.1 30.2 72.8 77.5 82.5 67.3 74.6 74.0 38.6 94.8 77.4 62.1 74.7 49.7 87.1 76.7 83.5 67.7 68.3 51.9 46.4 73.5 74.2 83.0 46.7 47.6 68.7 71.0 77.5 58.1 45.6 39.7 53.3 73.8 128.9 72.5 57.1 82.7 80.2 52.9 57.1 40.2 78.1 53.2 57.1 104.5 47.9 70.7 58.0 84.5 115.2 92.7 74.9 78.4 263.8 167.0 51.5 112.7 134.4 96.2 117.7 35.8 34.7 22.6 61.1 190.8 86.7 42.8 64.8 106.6 101.2 97.7 72.8 145.3 122.6 139.0 172.8 20.3 52.7 148.8 101.3 82.2 55.7 132.4 116.1 36.9 33.4 32.1 202.5 72.5 56.2 118.8 41.9 59.5 70.6 43.0 48.8 32.6 147.9 98.8 61.4 76.6 61.9 55.5 60.4 67.5 71.3 54.0 91.0 116.2 44.6 83.6 85.3 22.5 39.4 51.6 127.9 30.8 43.1 155.3 85.6 147.8 74.5 98.0 72.7 49.4 77.1 74.6 81.0 50.4 70.1 69.8 58.9 81.9 109.3 58.2 100.0 107.8 73.6 75.1 77.5 82.5 76.7 83.5 73.5 74.2 77.5 80.2 78.1 84.5 84.3 25.6 27.7 16.0 35.0 61.1 123.7 138.8 50.7 47.8 43.2 57.9 51.8 41.5 63.8 53.3 18.8 130.9 28.1 32.9 105.7 95.9 92.5 74.0 70.6 86.5 17.5 38.1 17.5 61.4 98.6 80.3 28.1 47.2 33.6 38.0 71.4 61.9 64.6 48.8 20.0 29.8 81.4 37.1 33.2 28.3 93.8 39.2 56.9 20.6 51.0 95.4 49.4 21.1 29.6 52.3 44.3 103.0 24.0 50.8 51.4 130.1 75.4 37.0 32.9 65.3 79.1 113.8 22.9 47.7 59.2 121.4 37.3 61.6 34.8 74.8 RRAS R-Ras ENSG00000126458 "RAS related" P10301 19 49635292-49640143 "Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 215.6;Pancreatic endocrine cells: 150.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 20.9;non-classical monocyte: 25.0" "Lineage enriched" "Detected in many" 7 "monocytes: 25.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010160, HPA060364, CAB069439" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010160: AB_2180086, CAB069439: AB_1622637, HPA060364: AB_2684264" "unprognostic (9.23e-2)" "unprognostic (6.37e-2)" "unprognostic (1.50e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (8.54e-2)" "unprognostic (4.55e-3)" "prognostic unfavorable (5.28e-4)" "unprognostic (2.16e-2)" "unprognostic (7.58e-2)" "unprognostic (1.39e-3)" "unprognostic (2.30e-2)" "prognostic unfavorable (1.54e-9)" "unprognostic (6.13e-2)" "unprognostic (3.42e-2)" "unprognostic (7.14e-3)" "unprognostic (2.74e-2)" 167.4 59.1 36.6 43.6 36.8 5.2 129.6 35.7 49.4 162.6 33.9 241.7 40.3 187.0 24.9 58.4 168.3 47.1 201.9 34.4 39.0 99.2 40.9 168.9 37.2 40.1 36.2 79.9 31.1 14.6 28.5 63.5 38.1 147.8 23.6 4.9 52.8 160.2 51.9 52.9 89.5 84.2 37.2 100.2 117.7 35.3 39.7 15.0 83.8 49.8 20.1 173.3 139.4 35.4 82.1 99.4 12.5 25.3 212.7 236.1 3.8 105.8 148.7 50.6 65.9 13.7 134.2 5.1 54.0 156.8 73.2 53.6 7.3 108.5 20.7 33.4 5.5 9.7 32.3 8.4 197.2 0.6 20.3 167.3 95.1 63.9 50.7 213.5 130.4 3.7 6.4 39.1 91.3 32.4 0.5 9.3 2.5 69.5 80.0 7.7 30.4 15.3 111.4 16.3 0.2 11.6 41.5 36.8 6.7 32.4 52.5 7.8 187.3 147.3 58.9 26.0 30.9 28.7 13.0 1.3 153.1 6.3 47.4 0.0 5.4 0.1 0.6 20.9 0.5 2.0 1.6 0.5 3.7 0.4 1.7 0.4 0.0 0.6 25.0 1.0 0.7 2.2 36.6 36.8 35.7 49.4 34.4 39.0 40.1 36.2 38.1 37.2 39.7 35.4 215.6 38.5 7.9 2.3 6.2 29.6 54.4 126.4 11.4 1.7 44.4 57.4 61.1 27.1 48.7 51.5 2.1 4.9 7.4 60.8 9.8 65.9 0.9 12.5 90.0 75.4 10.2 3.6 1.2 55.7 41.2 76.6 16.3 29.9 10.2 2.3 79.2 7.1 31.5 5.0 0.6 22.2 30.5 28.3 23.2 6.1 60.3 32.1 26.6 8.4 32.9 59.1 4.1 0.0 0.8 150.4 33.0 76.0 6.0 62.0 53.3 10.7 14.5 2.5 78.9 35.2 135.9 1.8 5.4 11.9 19.2 7.1 9.4 9.3 17.8 54.4 S1PR3 "EDG-3, EDG3" ENSG00000213694 "Sphingosine-1-phosphate receptor 3" "Q99500, Q6ZRZ4" 9 88990863-89005155 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 55.5;Sertoli cells: 65.7;Smooth muscle cells: 35.0;Theca cells: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "classical monocyte: 7.0" "Lineage enriched" "Detected in single" 18 "monocytes: 7.0" "Cell line enhanced" "Detected in many" "AF22: 116.0;ASC diff: 157.9;ASC TERT1: 158.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "prognostic favorable (5.91e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.91e-3)" "unprognostic (2.02e-1)" "unprognostic (4.41e-2)" "unprognostic (2.77e-2)" "unprognostic (5.22e-2)" "unprognostic (1.94e-2)" "unprognostic (3.15e-1)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.91e-6)" "unprognostic (4.43e-2)" "unprognostic (1.48e-2)" "unprognostic (3.93e-2)" "unprognostic (1.37e-1)" 18.3 25.0 5.8 10.6 6.4 3.2 11.2 6.9 6.7 32.2 10.7 14.8 4.5 17.2 6.2 17.6 26.0 14.2 17.5 6.3 11.2 36.9 6.1 8.9 11.4 16.1 9.8 5.1 11.7 1.7 17.0 15.1 7.7 20.1 3.4 4.2 3.9 11.9 4.4 3.1 10.7 36.0 8.4 13.2 12.5 2.2 12.4 4.7 4.8 8.2 9.4 20.4 20.9 13.2 0.5 17.7 116.0 6.0 157.9 158.7 0.1 24.8 61.4 17.0 17.0 0.2 0.0 0.0 0.3 37.2 16.6 0.2 0.3 18.0 11.5 0.0 1.2 0.0 23.3 0.1 13.7 8.1 0.1 28.6 1.0 22.2 4.0 13.2 29.9 17.0 2.1 0.1 4.7 17.1 14.3 8.7 11.2 0.8 6.2 1.5 0.0 0.1 0.3 7.1 1.5 8.1 23.4 5.7 0.0 22.8 2.7 7.4 60.3 25.4 10.3 27.8 4.1 0.0 0.1 0.0 36.8 7.1 9.1 0.3 7.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 2.1 5.8 6.4 6.9 6.7 6.3 11.2 16.1 9.8 7.7 8.4 12.4 13.2 3.0 0.0 1.7 3.6 0.0 10.1 9.5 1.8 2.8 1.0 9.9 3.7 9.2 1.5 1.7 1.8 2.1 17.9 0.1 0.0 0.0 0.3 0.0 2.1 55.5 10.6 0.0 0.0 0.5 0.5 1.3 21.5 0.5 2.4 0.0 3.8 1.8 1.6 2.4 3.3 1.7 0.0 0.0 1.8 4.0 0.5 3.7 4.4 0.0 7.5 6.9 7.1 0.0 0.0 0.2 0.9 0.0 6.8 0.2 7.0 0.0 1.4 2.9 1.6 65.7 16.1 35.0 0.0 1.2 1.5 3.3 5.5 2.2 65.8 0.0 6.4 SAMHD1 "AGS5, HDDC1, Mg11, MOP-5, SBBI88" ENSG00000101347 "SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1" Q9Y3Z3 20 36890229-36951843 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, DNA replication, Host-virus interaction, Immunity, Innate immunity" "Allosteric enzyme, Hydrolase" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 214.2;Endometrial ciliated cells: 173.8;Kupffer cells: 280.2;Macrophages: 326.4;monocytes: 257.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 510.8;BJ hTERT+ SV40 Large T+: 165.8;BJ hTERT+ SV40 Large T+ RasG12V: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047072 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 91000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane" "HPA047072: AB_2679921" "unprognostic (1.09e-1)" "unprognostic (7.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (2.15e-1)" "unprognostic (4.07e-2)" "unprognostic (2.03e-1)" "unprognostic (3.63e-1)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.44e-1)" "unprognostic (9.06e-2)" "unprognostic (3.18e-2)" "unprognostic (2.72e-2)" 79.5 39.9 11.9 94.3 12.4 11.5 65.7 11.6 12.2 39.1 33.2 58.4 29.4 33.0 9.1 45.8 81.8 40.2 60.5 11.4 16.6 12.2 26.1 68.0 78.0 16.8 15.0 38.0 42.2 14.0 21.7 36.0 17.9 26.3 28.8 5.5 32.6 18.1 23.8 27.8 55.2 44.1 17.6 94.2 45.0 12.6 18.0 29.3 31.7 20.7 51.2 55.3 39.9 26.4 29.9 10.9 3.7 15.6 510.8 101.8 5.5 10.8 37.7 165.8 187.8 39.1 11.2 64.4 19.9 14.4 94.9 21.2 34.7 27.8 30.9 17.4 20.6 5.3 18.8 30.9 39.3 28.2 5.1 96.4 1.0 45.3 1.9 13.3 26.4 0.0 13.7 18.8 5.4 12.0 0.0 19.2 7.9 18.3 25.9 2.8 21.7 35.3 15.7 8.2 23.0 4.2 20.2 10.2 28.2 4.7 20.5 125.4 13.9 11.5 13.5 25.1 28.5 7.3 20.3 21.7 14.5 3.2 7.1 1.4 147.7 4.8 52.2 174.4 47.0 4.5 55.7 53.3 278.6 3.1 55.5 47.6 18.5 56.2 167.0 96.4 95.8 144.3 11.9 12.4 11.6 12.2 11.4 16.6 16.8 15.0 17.9 17.6 18.0 26.4 48.7 28.9 25.5 4.2 19.4 6.4 2.3 7.8 5.7 5.5 6.9 5.8 17.3 14.3 35.3 1.8 4.2 2.6 214.2 2.6 0.0 10.3 3.3 173.8 12.7 44.3 6.0 30.7 8.6 10.2 3.3 71.4 13.3 40.6 12.6 10.5 42.5 20.1 137.2 6.7 8.5 5.7 8.2 280.2 52.3 4.8 82.3 326.4 5.4 36.5 257.9 25.1 116.4 14.1 3.5 7.5 31.3 96.3 54.8 1.9 1.1 1.9 104.4 2.9 59.2 9.6 31.9 10.2 4.9 12.1 5.8 2.9 102.6 9.7 5.5 4.9 SAR1A "SAR1, Sara, SARA1" ENSG00000079332 "Secretion associated Ras related GTPase 1A" Q9NR31 10 70147289-70170523 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006923, CAB022545, HPA048368" Supported Supported "Endoplasmic reticulum" NA NA 660000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "CAB022545: , HPA006923: AB_1856577, HPA048368: AB_2680373" "unprognostic (3.77e-2)" "unprognostic (7.13e-2)" "unprognostic (3.08e-3)" "unprognostic (3.13e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (7.00e-5)" "prognostic unfavorable (4.04e-4)" "unprognostic (1.60e-2)" "unprognostic (1.00e-1)" "unprognostic (1.02e-2)" "unprognostic (4.06e-2)" "unprognostic (2.06e-1)" "unprognostic (2.38e-3)" "unprognostic (1.76e-1)" "unprognostic (4.80e-2)" "unprognostic (1.10e-2)" "unprognostic (7.13e-2)" 77.1 52.8 41.8 38.4 43.5 163.2 48.1 45.1 45.7 43.1 53.3 39.1 26.6 41.0 47.0 41.4 37.3 35.0 44.8 43.8 48.3 43.3 70.2 51.4 36.7 42.8 44.9 41.0 33.9 44.2 37.9 76.0 44.0 38.9 35.5 42.0 39.9 38.9 51.1 38.5 34.5 49.7 47.3 40.7 37.9 23.5 48.4 33.2 39.8 56.3 38.4 45.8 36.2 52.1 85.8 56.3 75.7 131.9 246.1 143.1 61.1 128.3 154.4 115.6 140.0 169.7 78.2 74.4 67.1 153.7 52.8 96.6 94.5 75.9 111.6 103.9 44.3 54.1 65.8 82.5 112.4 86.7 56.6 155.9 68.4 76.4 133.2 119.0 63.8 55.9 68.7 105.9 110.0 60.0 73.8 72.6 65.2 55.6 141.3 70.8 84.4 42.5 88.7 69.7 42.6 73.8 98.0 134.6 72.2 66.8 65.8 59.7 88.6 63.7 94.3 92.2 91.3 72.3 141.3 114.0 84.9 111.7 48.7 75.5 63.5 74.0 88.0 80.9 94.8 47.7 68.5 85.9 58.5 38.6 65.7 88.7 67.9 103.3 72.9 44.8 53.2 95.9 41.8 43.5 45.1 45.7 43.8 48.3 42.8 44.9 44.0 47.3 48.4 52.1 88.4 128.2 110.2 6.8 53.5 235.7 138.0 120.2 25.0 38.6 99.2 62.4 74.7 57.2 105.3 49.7 33.3 120.6 109.8 51.6 54.8 78.4 3.0 52.3 85.8 85.2 42.7 46.1 21.2 77.3 199.0 127.8 23.9 89.7 53.2 46.3 69.7 114.1 101.0 26.9 22.2 72.1 65.1 51.2 208.9 5.6 54.7 68.1 113.8 21.5 58.4 61.9 75.2 16.1 26.4 78.8 56.2 58.6 97.7 141.4 59.1 95.9 67.1 33.4 78.9 73.7 158.8 64.1 51.8 37.2 248.8 238.9 86.3 45.2 53.2 175.2 SASH1 "dJ323M4.1, KIAA0790, SH3D6A" ENSG00000111961 "SAM and SH3 domain containing 1" O94885 6 148272304-148552048 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypotrichosis, Palmoplantar keratoderma, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 194.8;Astrocytes: 426.7;Microglial cells: 179.9;Oligodendrocyte precursor cells: 186.5;Oligodendrocytes: 328.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "classical monocyte: 1.2;intermediate monocyte: 2.6;non-classical monocyte: 1.3" "Lineage enriched" "Detected in single" 26 "monocytes: 2.6" "Cell line enhanced" "Detected in many" "ASC diff: 198.0;ASC TERT1: 74.7;fHDF/TERT166: 73.4;HUVEC TERT2: 75.0;WM-115: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029947, HPA029949" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "HPA029947: AB_10598915, HPA029949: AB_10602280" "unprognostic (9.71e-2)" "unprognostic (4.74e-2)" "unprognostic (5.32e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (3.55e-2)" "unprognostic (4.79e-3)" "unprognostic (6.69e-2)" "unprognostic (4.76e-2)" "unprognostic (2.06e-1)" "unprognostic (8.65e-3)" "unprognostic (9.94e-2)" "unprognostic (2.96e-1)" "unprognostic (2.13e-3)" "unprognostic (5.45e-2)" "unprognostic (3.53e-1)" "unprognostic (8.04e-3)" "unprognostic (1.54e-1)" 76.1 6.1 45.5 6.6 62.5 0.3 47.6 58.2 35.4 24.5 10.3 18.1 6.8 13.6 5.1 45.2 15.9 19.7 17.0 40.0 43.0 15.0 9.3 26.5 6.2 72.1 60.0 6.5 9.5 14.2 5.1 30.3 59.4 11.6 9.8 15.4 19.8 9.2 17.9 31.0 11.8 16.1 49.1 13.7 9.5 4.6 65.1 5.1 39.0 22.5 7.8 13.8 27.9 59.3 4.8 2.9 23.6 7.9 198.0 74.7 3.9 27.3 65.6 20.2 30.7 6.2 5.7 0.0 14.1 73.4 10.1 5.7 7.3 6.7 16.9 0.0 5.3 0.0 13.6 5.7 6.1 0.0 1.3 35.1 6.8 30.6 8.3 8.3 75.0 0.0 0.4 0.1 19.1 5.5 0.0 0.0 6.9 2.6 3.8 0.0 16.8 0.2 15.1 15.1 0.9 0.0 8.4 30.8 21.5 6.1 2.4 14.0 65.6 19.7 4.0 63.1 5.9 0.0 0.0 0.0 31.6 0.0 95.6 0.0 1.2 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 45.5 62.5 58.2 35.4 40.0 43.0 72.1 60.0 59.4 49.1 65.1 59.3 194.8 16.0 21.7 426.7 0.6 41.0 6.2 5.1 29.6 21.9 17.7 24.0 18.5 5.7 18.3 46.0 6.2 20.6 0.8 4.4 7.9 3.1 0.8 45.3 36.2 104.7 4.8 0.0 16.4 2.4 59.5 66.5 8.2 40.1 2.5 2.3 60.3 8.1 8.8 3.3 120.7 5.3 10.2 42.4 18.5 1.6 18.3 15.6 42.7 179.9 4.9 100.4 0.0 186.5 328.6 1.5 2.9 28.2 1.3 6.4 2.3 15.0 15.5 4.7 78.9 49.9 73.2 0.5 3.7 46.3 33.0 32.7 1.6 3.1 7.2 7.4 SBSN "HLAR698, UNQ698" ENSG00000189001 Suprabasin Q6UWP8 19 35523367-35528351 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1056.2;skin 1: 2444.7;vagina: 756.5" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 1017.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 355.2;melanoma: 153.1" "Group enriched" "Detected in some" 5 "basal ganglia: 3.9;cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.2;ASC TERT1: 107.5;HSkMC: 146.1;U-2197: 51.6;U-87 MG: 119.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062568, HPA067734" Enhanced Approved Vesicles "Secreted - unknown location" NA NA 89000000 "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA062568: AB_2684794, HPA067734: AB_2685894" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-2)" "unprognostic (1.23e-3)" "unprognostic (3.45e-3)" "unprognostic (2.56e-1)" "unprognostic (4.83e-4)" "unprognostic (4.31e-4)" "unprognostic (6.97e-2)" "unprognostic (9.08e-14)" "unprognostic (6.37e-2)" "unprognostic (6.51e-3)" "unprognostic (2.09e-1)" "unprognostic (1.36e-3)" 2.9 0.6 0.5 0.1 3.9 0.7 94.3 0.4 1.3 465.7 0.3 1.0 0.0 0.5 0.0 1056.2 0.2 0.3 1.4 0.5 0.4 0.4 1.7 0.9 0.0 0.5 0.4 0.7 1.5 0.0 0.9 0.3 0.5 0.5 0.0 0.0 351.8 0.0 13.1 2444.7 0.7 0.2 0.4 0.5 1.1 1.0 0.5 6.5 0.7 0.0 168.9 1.1 756.5 0.4 0.1 0.1 0.0 0.1 62.2 107.5 0.1 5.1 7.2 2.4 0.9 0.0 0.1 0.1 1.2 4.8 1.7 0.3 0.0 1.8 1.0 0.1 0.2 0.0 0.1 0.0 0.6 0.0 0.1 146.1 8.2 30.0 7.1 2.1 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 1.4 0.3 0.2 0.0 0.4 18.4 3.8 51.6 1.4 0.5 0.3 0.0 119.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.9 0.4 1.3 0.5 0.4 0.5 0.4 0.5 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 89.3 0.1 0.6 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1.4 0.8 1.8 0.0 0.0 0.2 0.6 0.2 3.1 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 25.2 4.0 0.0 0.2 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 1.0 0.2 0.2 13.4 1017.6 0.3 0.7 0.0 0.0 0.4 SCARA5 "FLJ23907, MGC45780, NET33" ENSG00000168079 "Scavenger receptor class A member 5" Q6ZMJ2 8 27869883-27992673 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 90.0" "Group enriched" "Detected in some" 4 "Fibroblasts: 174.0;Leydig cells: 135.8;Theca cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 121 "plasmacytoid DC: 21.1" "Lineage enriched" "Detected in single" 211 "dendritic cells: 21.1" "Cell line enriched" "Detected in some" 20 "ASC diff: 229.1" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 5 "spinal cord: 19.5" HPA024661 Approved NA NA 1400000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA024661: AB_1853902" "unprognostic (2.76e-2)" "unprognostic (7.20e-3)" "unprognostic (1.44e-2)" "unprognostic (3.53e-2)" "unprognostic (2.34e-2)" "unprognostic (4.62e-2)" "unprognostic (2.01e-1)" "unprognostic (2.15e-1)" "unprognostic (9.13e-2)" "unprognostic (2.40e-1)" "unprognostic (4.21e-2)" "unprognostic (1.10e-1)" "unprognostic (7.09e-6)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" 60.5 4.0 0.4 7.2 0.8 0.0 34.6 0.8 1.8 16.6 4.9 38.5 8.7 2.9 8.2 21.1 23.7 22.5 90.0 0.6 0.4 1.0 4.1 20.2 2.4 0.3 0.2 11.2 2.4 0.2 5.4 12.5 0.2 8.4 33.7 0.3 29.0 3.3 15.1 31.1 26.3 6.5 0.5 3.3 27.3 11.6 0.2 3.2 21.1 34.5 2.1 77.1 36.8 0.3 0.0 7.9 0.0 0.0 229.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 11.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 3.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.1 0.4 0.8 0.8 1.8 0.6 0.4 0.3 0.2 0.2 0.5 0.2 0.3 7.1 0.0 0.0 0.0 0.1 6.5 0.1 0.0 0.6 0.0 0.5 0.6 4.6 0.0 0.0 0.0 0.0 0.1 6.7 0.2 0.0 0.0 1.5 0.7 27.9 2.4 0.0 0.0 0.3 0.0 0.4 174.0 4.1 0.8 0.0 0.0 0.0 0.0 0.4 0.0 2.9 0.0 0.0 0.0 17.0 4.6 135.8 1.3 7.2 5.6 0.0 1.9 0.0 0.0 0.2 0.0 0.0 11.3 0.8 0.1 0.0 0.0 0.0 0.1 0.0 7.4 3.6 0.7 1.1 0.9 6.0 0.1 1.1 44.5 0.3 0.1 SCARB2 "CD36L2, HLGP85, LIMP-2, LIMPII, SR-BII" ENSG00000138760 "Scavenger receptor class B member 2" Q14108 4 76158737-76234536 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 12.5;classical monocyte: 14.1;intermediate monocyte: 26.0;myeloid DC: 8.2;non-classical monocyte: 24.9;plasmacytoid DC: 28.9" "Group enriched" "Detected in all" 5 "dendritic cells: 28.9;granulocytes: 12.5;monocytes: 26.0" "Cell line enhanced" "Detected in many" "ASC diff: 499.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015415, HPA018014" Supported Approved Cytosol NA NA 9200 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 35: Glandular cells - Unknown function" Cytosol "CAB015415: AB_831511, HPA018014: AB_1852881" "prognostic unfavorable (2.82e-5)" "unprognostic (2.73e-2)" "unprognostic (4.09e-2)" "unprognostic (4.96e-2)" "unprognostic (4.17e-3)" "unprognostic (1.12e-3)" "unprognostic (2.08e-1)" "unprognostic (5.48e-2)" "unprognostic (4.06e-1)" "unprognostic (1.25e-2)" "unprognostic (4.11e-2)" "unprognostic (1.67e-1)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (6.88e-2)" "unprognostic (5.06e-2)" "unprognostic (3.89e-2)" 60.6 24.0 33.5 27.7 63.5 7.3 56.7 58.9 38.9 60.8 18.9 61.6 39.2 44.1 58.4 33.9 45.4 60.0 61.6 29.6 48.6 46.8 89.9 77.1 20.2 62.2 49.6 58.9 58.9 63.6 11.1 80.2 62.5 72.3 64.0 53.2 80.5 55.4 89.8 26.0 49.1 57.8 60.1 47.0 60.7 19.4 50.7 21.3 65.9 81.3 20.6 65.3 25.1 92.9 39.8 38.4 48.9 97.1 499.7 242.0 35.8 131.5 250.2 114.0 178.2 72.5 112.3 0.0 85.1 262.3 109.6 28.3 28.3 78.9 96.0 138.8 30.1 3.2 32.9 25.3 129.9 19.0 12.1 186.9 72.3 117.3 54.5 268.9 200.6 10.0 15.6 188.6 159.2 58.2 1.6 4.0 9.7 120.3 23.6 23.3 82.7 42.0 64.4 43.6 101.3 110.2 104.7 61.3 115.5 49.3 34.6 17.1 131.3 125.9 48.5 104.7 47.5 167.6 98.8 0.2 158.1 22.2 170.9 12.5 14.1 3.1 2.8 26.0 2.6 3.8 1.9 1.5 8.2 3.0 2.6 4.3 1.9 1.1 24.9 28.9 3.0 6.1 33.5 63.5 58.9 38.9 29.6 48.6 62.2 49.6 62.5 60.1 50.7 92.9 89.0 176.3 52.4 47.3 20.1 24.0 90.5 64.8 34.1 109.6 69.7 36.4 53.0 87.2 52.1 99.3 60.5 35.3 43.6 109.0 7.9 119.9 7.1 50.3 74.0 69.9 102.4 28.6 57.4 72.9 47.5 108.3 40.8 88.8 3.8 84.8 79.6 108.7 143.4 60.6 55.4 77.1 44.7 165.7 27.5 5.6 45.4 76.2 67.6 38.4 43.5 87.2 6.2 106.1 201.1 78.0 68.3 66.5 82.2 133.5 103.2 27.6 54.4 81.7 92.1 91.0 68.1 18.2 16.5 34.8 33.8 59.4 16.3 56.5 55.3 93.4 SCD "FADS5, SCDOS" ENSG00000099194 "Stearoyl-CoA desaturase" O00767 10 100347233-100364826 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1233.7;brain: 839.9;liver: 583.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 389.6;Granulosa cells: 187.3;Hepatocytes: 840.3;Oligodendrocytes: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 2534.2;CAPAN-2: 1824.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012107, HPA063921" Approved Enhanced "Endoplasmic reticulum" No Yes "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA012107: AB_1856610, HPA063921: AB_2685154" "unprognostic (2.10e-1)" "unprognostic (2.62e-3)" "unprognostic (7.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (1.13e-1)" "unprognostic (3.88e-2)" "unprognostic (6.53e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (7.18e-2)" "unprognostic (3.27e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (7.79e-5)" 1233.7 131.2 408.7 25.7 525.8 23.0 261.5 535.7 522.1 43.2 156.6 42.9 93.1 15.4 25.5 107.8 5.0 28.7 47.1 349.1 457.5 18.5 583.8 142.8 17.2 775.0 508.9 49.6 22.6 79.5 10.3 19.9 637.8 100.1 39.7 17.9 112.6 11.2 6.1 27.0 36.0 15.9 574.4 15.3 25.2 51.8 538.7 18.4 13.0 7.2 21.0 22.5 41.9 839.9 411.2 373.3 777.6 536.4 2534.2 1449.4 158.2 43.4 948.3 101.6 536.6 323.8 1824.4 173.3 33.7 102.2 461.8 716.4 433.7 1549.5 88.9 59.4 179.6 97.5 219.3 653.4 488.4 136.9 100.9 795.5 459.4 395.0 688.9 273.1 196.2 375.3 275.4 513.3 41.7 646.8 155.9 163.3 270.7 120.7 106.3 72.6 287.4 550.4 443.8 455.3 48.9 185.3 85.8 399.7 834.9 224.2 447.7 291.3 79.0 10.0 115.9 9.1 89.8 141.4 81.5 262.9 184.4 416.0 65.9 0.0 0.8 0.0 1.4 1.6 2.3 0.6 0.5 0.7 2.7 0.9 0.4 1.3 0.1 1.4 0.0 1.5 0.0 1.2 408.7 525.8 535.7 522.1 349.1 457.5 775.0 508.9 637.8 574.4 538.7 839.9 3.8 54.5 389.6 34.0 15.7 3.7 4.5 121.8 0.6 6.5 16.1 6.2 11.2 28.6 66.2 0.0 6.2 3.0 4.7 21.5 0.0 14.6 52.6 13.9 9.0 12.5 25.8 15.8 4.8 67.9 71.7 15.9 25.0 26.9 6.3 187.3 32.9 840.3 34.1 26.9 5.2 16.4 52.9 113.5 4.2 93.0 3.7 21.2 58.7 8.4 10.2 11.9 2.1 18.6 451.5 29.6 2.7 1.5 3.7 31.4 16.2 4.9 31.0 6.2 0.0 3.6 25.7 2.0 1.2 26.7 2.3 17.4 6.6 97.8 38.9 8.2 SCPEP1 RISC ENSG00000121064 "Serine carboxypeptidase 1" Q9HB40 17 56978129-57006768 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 300.9" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 456.2;Club cells: 304.9;Respiratory ciliated cells: 397.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 319.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 389.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039102, HPA057200" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA039102: AB_10673605, HPA057200: AB_2683365" "unprognostic (5.83e-3)" "unprognostic (7.43e-3)" "unprognostic (4.47e-2)" "unprognostic (2.96e-1)" "unprognostic (9.26e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.00e-3)" "unprognostic (1.68e-1)" "unprognostic (1.70e-1)" "unprognostic (3.56e-3)" "unprognostic (1.40e-1)" "unprognostic (3.25e-1)" "unprognostic (7.28e-2)" "unprognostic (8.89e-2)" "unprognostic (8.33e-2)" "unprognostic (1.68e-1)" 64.1 121.5 25.7 32.6 26.4 75.8 91.0 27.3 42.9 69.8 34.5 46.9 31.4 37.5 73.1 54.8 48.5 71.2 60.1 27.2 30.9 88.6 32.0 95.1 48.7 30.1 29.5 53.6 17.0 300.9 28.7 20.8 30.6 61.6 33.7 8.1 90.0 102.9 15.8 46.3 40.3 60.9 28.7 44.8 54.2 14.3 28.4 14.6 135.1 32.5 60.6 71.1 51.1 33.6 48.3 20.9 49.4 41.4 389.3 85.6 26.0 23.3 119.6 41.9 77.8 13.7 33.3 63.3 126.4 55.9 65.8 44.0 22.0 105.4 46.8 82.0 36.1 19.8 28.2 8.7 89.1 39.1 190.1 103.7 45.0 52.0 43.0 37.5 72.3 24.3 5.1 257.9 59.1 20.3 19.9 100.4 20.4 15.2 39.3 24.2 53.8 41.4 9.3 143.7 13.8 33.8 56.3 45.6 33.3 57.1 19.1 104.1 34.1 118.3 29.9 68.8 26.5 250.5 187.2 35.9 88.1 28.5 34.4 2.1 228.5 319.0 11.8 137.1 8.0 56.0 8.2 8.3 105.7 55.1 11.3 12.3 34.8 23.7 141.0 18.0 10.2 118.7 25.7 26.4 27.3 42.9 27.2 30.9 30.1 29.5 30.6 28.7 28.4 33.6 48.8 44.8 61.8 25.1 52.7 23.7 208.6 456.2 37.5 12.7 52.4 110.7 32.5 10.0 304.9 95.6 16.7 9.9 20.5 2.0 19.6 22.2 1.0 51.5 24.5 27.1 24.4 21.2 37.2 6.8 19.4 115.4 4.6 13.6 8.2 4.3 62.8 15.7 160.5 10.1 24.9 5.0 126.1 135.0 33.7 3.4 64.3 110.2 24.9 20.6 142.2 18.9 25.7 21.1 20.7 4.8 1.6 68.1 39.0 74.1 62.4 29.7 397.8 17.0 52.6 28.1 63.2 4.4 12.3 38.1 19.9 11.1 18.8 67.1 8.0 122.6 SCUBE3 "CEGF3, FLJ34743" ENSG00000146197 "Signal peptide, CUB domain and EGF like domain containing 3" Q8IX30 6 35213956-35253079 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "thyroid gland: 28.9" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 10.8;Horizontal cells: 10.1;Rod photoreceptor cells: 7.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 26.0;ASC diff: 76.7;ASC TERT1: 102.2;HSkMC: 48.1;hTEC/SVTERT24-B: 30.1;U-138 MG: 29.1;WM-115: 25.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040606 Uncertain Approved "Plasma membrane" "Secreted to blood" NA NA 1890000 490000 "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA040606: AB_10795383" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (2.22e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (2.00e-2)" "unprognostic (7.41e-2)" "unprognostic (1.57e-1)" "unprognostic (2.64e-2)" "unprognostic (4.83e-8)" "unprognostic (1.54e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.06e-3)" 1.7 2.4 0.7 0.9 1.1 0.1 0.4 2.0 1.0 0.5 2.9 4.2 0.1 0.6 0.9 0.7 0.8 0.5 3.4 0.5 0.6 2.9 0.1 0.7 0.1 0.8 1.0 0.5 0.1 0.1 1.7 0.7 0.3 2.2 0.9 1.4 0.2 4.5 0.3 0.8 0.7 0.9 0.1 0.2 1.4 1.1 0.7 0.1 28.9 0.0 0.2 5.1 0.9 0.8 0.0 0.1 26.0 0.2 76.7 102.2 0.3 6.7 3.3 0.1 0.1 0.5 0.1 0.0 0.9 15.5 0.0 0.0 5.3 0.0 0.4 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.0 48.1 0.0 30.1 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.3 0.0 0.0 1.2 0.0 0.4 0.1 0.0 0.0 0.1 2.9 0.5 0.0 0.1 0.7 1.9 10.2 0.7 0.1 1.5 29.1 1.3 0.0 0.2 0.1 0.0 0.0 4.6 0.0 25.2 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.0 0.7 1.1 2.0 1.0 0.5 0.6 0.8 1.0 0.3 0.1 0.7 0.8 0.2 0.0 0.6 0.7 0.5 0.0 0.2 0.4 0.0 2.6 0.3 0.0 3.5 0.0 2.0 1.8 2.1 1.2 0.5 0.0 0.0 0.0 2.1 1.2 0.4 0.6 10.8 0.0 2.2 0.0 2.1 1.3 0.0 0.4 1.3 0.5 0.0 0.1 0.3 10.1 3.2 0.1 0.0 0.6 0.4 3.3 0.9 0.2 1.8 0.0 0.1 3.0 0.0 4.0 3.5 0.1 0.0 3.8 0.4 0.1 0.0 0.1 0.9 7.1 0.0 0.6 3.2 0.5 2.1 0.0 0.0 0.7 0.2 0.1 0.0 0.2 SDF2 ENSG00000132581 "Stromal cell derived factor 2" Q99470 17 28648346-28662189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042799 Approved Vesicles "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA042799: AB_10794533" "unprognostic (3.91e-1)" "unprognostic (2.79e-1)" "unprognostic (2.03e-1)" "unprognostic (5.77e-3)" "unprognostic (3.90e-2)" "unprognostic (1.88e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.28e-3)" "unprognostic (3.20e-3)" "unprognostic (3.02e-1)" "unprognostic (1.04e-2)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.39e-3)" "unprognostic (2.21e-1)" "unprognostic (7.75e-3)" "unprognostic (6.61e-2)" 16.2 32.2 14.6 8.7 14.6 8.8 14.2 14.9 15.2 17.5 18.5 15.7 8.0 14.4 27.2 13.8 17.3 13.0 17.5 14.9 16.3 18.5 23.2 15.4 9.4 15.4 15.3 19.7 19.9 20.1 19.1 20.5 16.0 18.2 11.1 6.6 21.8 15.7 14.7 11.5 13.0 14.4 15.3 16.1 15.3 9.4 15.9 12.7 16.2 12.9 8.1 20.2 14.3 14.9 18.8 54.3 25.2 18.7 107.1 29.6 18.0 53.6 48.4 39.6 49.8 34.6 23.5 8.0 47.8 57.6 36.6 30.5 24.7 22.6 27.8 62.3 29.8 13.7 26.6 28.6 30.9 8.1 17.2 53.7 28.5 38.3 8.8 34.4 39.9 11.0 14.9 19.4 45.1 35.9 20.7 22.2 12.9 48.8 19.2 12.5 37.1 24.8 45.3 29.6 15.6 18.1 42.3 32.4 30.3 37.5 43.7 10.4 45.0 21.0 23.3 24.2 31.2 25.2 35.2 11.9 32.0 12.9 23.9 189.1 45.1 129.1 64.4 39.6 62.6 50.8 52.2 62.8 30.0 44.4 47.1 55.9 203.1 71.1 42.1 62.5 74.2 59.7 14.6 14.6 14.9 15.2 14.9 16.3 15.4 15.3 16.0 15.3 15.9 14.9 61.1 25.6 21.7 10.4 45.5 34.0 59.1 125.6 41.5 26.4 49.4 44.6 13.1 38.6 71.1 42.3 25.0 130.3 74.0 82.8 29.4 74.8 7.4 36.2 43.6 52.2 57.1 37.5 11.1 47.2 109.0 52.6 27.5 44.9 21.0 47.2 53.2 46.2 56.7 13.5 12.2 57.5 71.2 44.9 49.7 3.9 76.1 38.1 37.4 8.4 50.2 49.9 56.7 11.1 17.8 80.4 90.4 66.5 46.2 54.1 88.0 50.7 47.8 31.1 72.3 36.7 48.1 30.5 32.1 40.6 37.6 211.0 53.2 86.0 46.2 86.9 SDF4 Cab45 ENSG00000078808 "Stromal cell derived factor 4" Q9BRK5 1 1216909-1232067 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 406.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011249, HPA011895, CAB015227" Supported Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA 2600000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "CAB015227: , HPA011249: AB_2668468, HPA011895: " "unprognostic (1.98e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (3.63e-1)" "unprognostic (2.38e-3)" "unprognostic (5.88e-2)" "unprognostic (7.95e-3)" "unprognostic (3.73e-3)" "unprognostic (1.06e-1)" "unprognostic (2.01e-1)" "unprognostic (8.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.04e-2)" 86.5 91.8 44.2 78.8 47.8 56.2 80.2 47.2 65.3 84.4 72.5 95.9 117.1 91.8 43.9 66.3 74.6 66.2 134.6 45.5 44.8 89.6 160.7 82.0 53.4 53.2 46.1 85.4 104.6 61.5 78.5 73.3 47.0 76.9 60.4 25.7 83.5 52.2 78.9 72.9 116.8 58.2 43.5 78.0 93.6 71.7 50.5 34.6 81.8 47.7 39.6 82.2 71.6 45.9 139.7 123.7 67.1 214.0 320.0 160.4 80.5 266.1 241.4 191.2 159.4 147.0 236.2 87.8 201.8 258.0 137.4 140.4 77.5 117.1 58.2 147.9 133.0 153.6 185.7 207.8 147.4 156.7 199.2 199.0 59.5 144.6 81.2 186.5 155.9 57.3 129.2 225.0 95.7 101.1 77.8 158.9 61.7 158.0 167.1 85.8 86.5 234.4 127.2 66.4 243.3 86.7 177.2 208.2 182.8 59.0 108.0 176.7 198.8 196.2 107.0 149.5 154.2 138.9 141.2 144.6 222.9 289.7 87.1 14.4 21.5 30.8 19.3 14.6 14.6 13.5 27.6 28.4 21.9 16.8 16.0 14.1 16.9 26.8 23.2 14.0 25.1 11.8 44.2 47.8 47.2 65.3 45.5 44.8 53.2 46.1 47.0 43.5 50.5 45.9 92.9 22.4 19.2 18.6 62.5 119.8 74.0 24.6 46.7 34.5 51.2 47.6 35.7 68.6 28.9 49.7 18.8 124.1 68.4 240.0 11.7 79.0 39.1 49.0 76.2 77.8 65.5 32.8 21.1 71.4 284.4 117.1 81.1 60.8 36.2 61.4 76.4 117.1 122.4 38.7 23.5 174.9 30.5 73.7 154.8 36.8 95.4 62.8 167.2 13.1 50.8 64.9 111.2 13.6 17.5 73.0 213.5 76.0 202.5 101.5 406.2 57.7 18.4 40.0 59.2 69.8 75.1 101.7 63.5 53.2 114.2 168.0 73.4 88.7 181.0 71.1 SEMA3G "FLJ00014, sem2" ENSG00000010319 "Semaphorin 3G" Q9NS98 3 52433035-52445103 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 80.1;breast: 64.2" "Cell type enriched" "Detected in many" 6 "Adipocytes: 151.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "T-reg: 1.4" "Lineage enriched" "Detected in single" 15 "T-cells: 1.4" "Cell line enhanced" "Detected in some" "ASC diff: 26.1;Hep G2: 7.1;HUVEC TERT2: 7.4;THP-1: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001761 Uncertain "Secreted to blood" NA NA 5600000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA001761: AB_1079902" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "unprognostic (7.08e-2)" "unprognostic (1.47e-2)" "unprognostic (2.85e-1)" "unprognostic (5.79e-4)" "unprognostic (5.20e-3)" "unprognostic (9.14e-2)" "unprognostic (5.54e-2)" "unprognostic (5.64e-2)" "unprognostic (1.34e-3)" "unprognostic (4.14e-1)" "prognostic favorable (8.86e-5)" "unprognostic (5.63e-2)" "unprognostic (2.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.14e-1)" 80.1 1.9 9.9 3.4 9.4 0.1 64.2 18.9 11.4 5.1 6.2 6.8 3.0 5.9 1.3 4.5 5.2 5.9 18.6 8.4 9.0 19.8 1.3 23.9 1.6 10.8 10.0 3.2 3.1 1.8 2.4 26.7 11.3 4.6 3.7 0.4 10.6 2.5 12.8 12.7 9.6 3.9 9.9 8.0 5.7 1.3 12.1 1.7 7.7 18.6 1.8 8.3 7.8 9.1 0.0 0.1 0.1 0.2 26.1 0.2 2.5 0.0 0.0 0.0 0.0 0.7 0.3 3.3 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.2 3.9 0.2 7.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 7.4 2.6 0.0 0.4 0.0 0.3 0.2 4.3 1.2 0.7 0.1 0.0 0.0 4.1 0.0 0.3 0.5 0.5 0.0 0.4 0.5 0.1 1.9 6.5 2.9 0.1 2.4 0.0 0.0 0.5 2.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 9.9 9.4 18.9 11.4 8.4 9.0 10.8 10.0 11.3 9.9 12.1 9.1 151.5 3.2 1.3 0.0 0.3 0.4 0.1 0.1 0.0 1.7 5.1 5.5 10.7 0.0 0.0 3.7 0.0 1.7 0.9 0.3 0.0 0.0 3.0 2.8 1.6 20.4 9.6 0.0 0.0 0.0 0.2 3.6 1.1 5.8 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.3 5.0 0.3 0.5 0.0 24.4 0.0 0.5 0.0 0.0 0.0 0.0 0.1 1.2 0.2 0.0 9.4 0.0 0.1 0.2 0.0 4.1 3.0 0.1 0.1 0.5 0.1 7.5 0.4 0.1 0.2 0.0 SERINC1 "KIAA1253, TDE1L, TDE2, TMS-2" ENSG00000111897 "Serine incorporator 1" Q9NRX5 6 122443351-122471807 "Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035738, HPA035739" Uncertain Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA035738: AB_10672990, HPA035739: AB_10669536" "unprognostic (2.83e-3)" "unprognostic (2.68e-3)" "unprognostic (1.59e-1)" "unprognostic (7.67e-2)" "unprognostic (2.65e-1)" "unprognostic (2.84e-2)" "unprognostic (2.04e-1)" "unprognostic (7.45e-2)" "unprognostic (9.84e-2)" "unprognostic (8.27e-2)" "unprognostic (9.07e-3)" "unprognostic (2.84e-1)" "unprognostic (5.50e-3)" "unprognostic (1.80e-3)" "unprognostic (9.22e-2)" "unprognostic (3.58e-1)" "unprognostic (1.00e-2)" 213.6 242.8 220.4 93.2 248.8 148.2 157.8 237.5 334.0 151.4 178.5 104.6 99.4 146.6 108.1 94.9 104.4 128.0 163.7 248.3 257.3 194.1 241.3 160.5 96.8 258.9 243.3 164.4 100.4 243.3 71.7 195.1 282.9 139.6 100.1 225.5 97.1 143.3 152.6 79.0 114.3 141.7 268.4 123.6 96.5 65.6 241.3 89.7 203.1 194.8 79.5 121.7 84.8 306.8 40.5 49.1 121.7 111.8 450.2 245.1 64.5 208.4 259.8 111.6 171.6 57.8 106.9 27.1 159.7 236.5 127.9 78.7 72.6 90.2 166.1 87.1 86.0 76.9 79.0 105.9 201.3 77.5 146.3 256.7 173.0 139.0 190.8 256.4 98.1 69.9 77.4 149.3 233.8 46.8 35.1 51.4 39.7 63.5 61.9 42.5 60.0 66.5 240.3 70.1 63.6 114.5 92.3 101.2 146.8 107.4 70.0 107.1 201.3 133.7 57.9 110.8 109.9 112.4 134.4 35.9 176.8 62.1 159.5 158.3 43.0 92.6 44.7 53.2 48.1 27.7 45.9 43.3 35.9 23.7 53.2 46.9 108.7 51.7 62.0 28.0 54.2 56.0 220.4 248.8 237.5 334.0 248.3 257.3 258.9 243.3 282.9 268.4 241.3 306.8 167.8 150.6 99.2 44.4 73.9 66.2 81.1 55.7 61.5 114.4 71.7 57.1 156.2 87.2 58.9 77.3 70.9 53.8 80.9 88.8 9.8 63.0 3.2 54.9 103.3 130.0 84.5 81.5 92.5 48.7 57.7 131.4 39.8 106.8 124.0 58.1 127.8 132.1 73.1 138.0 145.7 41.8 36.7 158.2 86.4 10.0 126.8 107.4 94.3 65.6 58.1 97.2 58.7 48.2 134.0 78.4 43.6 131.3 80.0 86.1 80.1 44.0 56.1 70.6 59.2 105.1 110.6 25.7 17.0 39.0 74.9 119.7 100.7 99.8 32.7 97.1 SERINC3 "AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1" ENSG00000132824 "Serine incorporator 3" Q13530 20 44496221-44522085 "Predicted membrane proteins, Transporters" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 558.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048116 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA048116: AB_2680269" "unprognostic (3.16e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (2.60e-1)" "unprognostic (2.74e-1)" "unprognostic (7.34e-2)" "unprognostic (1.85e-3)" "unprognostic (6.26e-2)" "unprognostic (7.41e-2)" "unprognostic (3.11e-1)" "unprognostic (8.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.60e-2)" "unprognostic (1.30e-3)" "unprognostic (4.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.27e-1)" "unprognostic (1.64e-2)" 81.6 91.6 50.1 49.3 60.0 48.7 61.8 57.8 80.4 73.3 22.4 56.6 47.2 62.4 48.9 65.2 54.8 68.9 72.8 66.1 60.3 49.2 92.7 67.7 46.4 57.6 56.7 67.6 50.3 107.0 44.6 115.8 61.5 57.7 63.2 47.9 66.3 63.5 81.6 63.9 53.3 70.1 56.8 57.1 54.1 110.2 55.7 60.0 81.5 81.1 50.3 63.3 50.1 67.9 70.3 73.9 34.8 44.1 297.4 211.8 53.7 140.8 243.1 111.5 101.3 167.3 169.2 51.0 187.5 168.8 127.1 123.0 41.9 144.9 117.3 59.5 47.1 59.7 71.9 85.7 161.4 74.2 124.5 152.1 207.4 109.7 163.3 135.3 110.0 81.6 67.5 146.2 117.7 88.2 76.5 58.9 20.5 91.6 110.9 38.1 51.9 78.5 88.7 79.5 43.4 32.9 135.2 129.8 91.8 47.9 93.0 82.6 141.5 262.1 43.3 117.0 99.1 86.2 102.0 38.9 195.3 51.7 83.9 217.1 92.6 119.4 96.5 96.7 98.4 57.6 82.9 94.5 95.4 63.4 84.7 85.0 177.3 111.0 113.5 87.4 104.4 137.7 50.1 60.0 57.8 80.4 66.1 60.3 57.6 56.7 61.5 56.8 55.7 67.9 139.7 73.7 70.7 20.5 52.1 54.8 75.3 96.5 60.3 39.2 55.3 44.4 75.9 78.6 84.7 47.8 35.5 85.8 86.1 84.4 15.6 77.2 239.8 44.5 76.2 115.1 66.4 94.9 58.7 69.9 85.6 97.5 41.3 65.1 102.5 32.9 122.4 105.7 57.7 45.4 52.4 60.4 71.2 93.5 50.0 558.0 105.0 79.7 39.2 34.7 44.2 47.4 37.0 27.6 63.8 100.4 63.8 114.0 76.1 75.3 55.6 24.6 65.4 36.6 98.6 69.5 88.9 210.9 99.3 54.6 84.1 165.4 72.0 85.9 54.7 82.2 SERPINF1 "EPC-1, PEDF, PIG35" ENSG00000132386 "Serpin family F member 1" P36955 17 1762029-1777565 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1875.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 697.8;Cytotrophoblasts: 795.6;Fibroblasts: 951.9;Hepatocytes: 765.0;Leydig cells: 1818.0;Peritubular cells: 1045.7" "Cancer enhanced" "Detected in all" "liver cancer: 245.2" "Region enhanced" "Detected in many" "hippocampal formation: 85.4" "Immune cell enriched" "Detected in many" 18 "plasmacytoid DC: 1454.4" "Lineage enriched" "Detected in all" 121 "dendritic cells: 1454.4" "Group enriched" "Detected in many" 4 "ASC diff: 1232.0;ASC TERT1: 956.3;Hep G2: 606.0;HHSteC: 410.6;HSkMC: 1313.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005825 Uncertain "Secreted to blood" NA NA 9290000000 44000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA005825: AB_1079921" "unprognostic (3.85e-1)" "prognostic favorable (5.49e-4)" "unprognostic (9.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.32e-3)" "unprognostic (2.33e-1)" "unprognostic (7.88e-2)" "unprognostic (5.92e-2)" "unprognostic (1.69e-1)" "unprognostic (4.18e-2)" "prognostic unfavorable (1.40e-8)" "unprognostic (2.11e-3)" "unprognostic (2.82e-1)" "unprognostic (4.53e-3)" "unprognostic (1.25e-3)" 535.5 57.5 5.7 124.2 9.6 11.9 490.2 17.9 28.0 558.7 1875.2 131.3 41.9 358.2 90.2 109.3 557.4 559.7 376.5 85.4 1.1 35.1 974.8 158.9 133.5 0.1 5.1 408.3 207.6 11.2 62.4 311.6 1.3 202.8 52.0 61.4 124.6 105.8 434.8 162.9 131.7 221.7 2.8 133.2 124.7 277.7 25.4 106.2 193.1 465.5 117.7 323.4 273.5 7.0 0.5 3.7 2.8 2.0 1232.0 956.3 20.4 56.8 49.8 0.6 0.0 9.7 0.5 2.3 1.9 71.8 0.3 3.2 86.0 4.4 0.0 0.6 46.0 1.0 1.2 606.0 410.6 1.1 1.1 1313.4 6.9 0.9 1.1 11.4 0.6 4.2 117.5 0.4 63.2 0.2 7.0 7.2 30.7 0.3 1.0 2.9 219.9 1.6 0.1 6.0 1.9 42.2 0.7 0.7 57.0 3.4 6.7 184.2 2.0 0.5 17.6 14.1 1.2 0.7 2.4 28.1 1.7 0.6 0.8 0.1 12.0 1.1 0.6 4.4 0.4 9.0 0.7 0.9 79.8 5.2 2.0 5.5 1.7 1.3 0.2 1454.4 0.8 14.2 5.7 9.6 17.9 28.0 85.4 1.1 0.1 5.1 1.3 2.8 25.4 7.0 59.0 3.2 10.4 0.3 10.8 95.0 238.0 697.8 27.9 59.3 6.7 71.2 12.1 11.5 167.7 1.8 223.1 795.6 226.1 0.0 0.0 0.3 11.2 12.5 372.4 26.2 0.0 19.2 5.3 24.5 98.7 951.9 11.2 6.7 22.9 1.7 28.2 765.0 151.6 3.3 2.6 0.0 366.2 60.4 262.6 53.0 1818.0 79.0 108.5 9.4 79.0 11.6 1.0 0.5 2.0 6.8 0.1 1045.7 7.0 155.5 0.2 27.3 105.5 39.1 19.7 193.3 202.8 12.7 8.7 4.5 78.6 534.8 14.3 10.2 0.3 47.7 SERPING1 "C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2" ENSG00000149131 "Serpin family G member 1" P05155 11 57597387-57619171 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Complement pathway, Fibrinolysis, Hemostasis, Immunity, Innate immunity" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2622.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 726.4;Ductal cells: 604.0;Fibroblasts: 793.6;Hepatocytes: 2530.0;Leydig cells: 735.3" "Cancer enhanced" "Detected in all" "liver cancer: 609.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 65.2;plasmacytoid DC: 60.6" "Group enriched" "Detected in many" 243 "dendritic cells: 60.6;granulocytes: 65.2;monocytes: 25.7" "Group enriched" "Detected in many" 6 "ASC diff: 1372.2;ASC TERT1: 694.9;HSkMC: 1159.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 194.1" "CAB026161, HPA048738" Supported "Secreted to blood" NA NA 28000000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "CAB026161: , HPA048738: AB_2680505" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (4.26e-2)" "unprognostic (4.38e-2)" "unprognostic (2.32e-1)" "unprognostic (4.12e-3)" "unprognostic (2.13e-1)" "unprognostic (8.95e-2)" "prognostic favorable (8.03e-4)" "unprognostic (5.92e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.60e-2)" "unprognostic (4.14e-2)" "unprognostic (2.56e-1)" "unprognostic (1.17e-1)" 971.5 144.2 27.4 90.0 27.5 10.9 733.0 27.1 36.0 629.4 53.4 358.7 52.0 616.7 163.3 162.0 793.2 533.0 547.1 26.2 34.8 337.3 2622.4 785.0 147.6 67.4 34.7 918.3 267.5 55.2 138.2 198.9 34.2 329.3 97.0 34.5 250.5 258.1 151.8 293.5 283.5 226.8 42.3 240.7 344.8 50.6 37.2 36.1 338.2 173.4 64.4 555.9 519.8 35.1 0.0 0.0 48.2 0.0 1372.2 694.9 7.3 74.2 57.0 16.8 30.7 2.5 0.0 0.0 96.7 42.1 0.0 0.0 0.4 4.7 9.4 0.0 0.1 33.7 0.0 1.7 170.3 0.9 5.4 1159.0 15.5 5.7 0.2 6.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 1.3 46.6 0.0 0.0 4.3 4.0 0.7 7.4 0.0 0.2 14.4 0.3 0.0 0.9 41.8 0.2 3.3 0.0 0.8 21.2 0.7 0.0 0.2 0.4 0.6 0.2 0.5 0.0 0.0 18.3 0.3 0.0 25.7 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 65.2 0.2 11.5 60.6 0.0 5.7 27.4 27.5 27.1 36.0 26.2 34.8 67.4 34.7 34.2 42.3 37.2 35.1 162.1 118.6 110.8 5.5 8.0 75.8 61.2 7.1 24.5 0.8 24.2 57.7 28.7 726.4 57.5 158.2 0.0 37.1 15.3 0.0 43.0 604.0 4.8 76.0 297.4 150.5 0.0 69.2 3.6 44.0 93.4 793.6 8.6 69.6 7.6 8.3 260.5 2530.0 43.6 0.0 6.2 0.1 2.0 118.9 94.2 25.6 735.3 46.9 90.7 15.9 10.4 57.2 0.0 3.5 0.5 41.4 0.0 228.7 4.5 32.4 0.0 53.5 23.1 4.5 269.5 143.6 259.6 2.5 10.4 9.0 59.5 25.2 16.8 3.4 0.0 37.4 SESTD1 "DKFZp434O0515, Solo" ENSG00000187231 "SEC14 and spectrin domain containing 1" Q86VW0 2 179101678-179264832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 175.5;Horizontal cells: 301.2;Oligodendrocytes: 311.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058236, HPA077408" Approved Enhanced "Intermediate filaments" NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Intermediate filaments" "HPA058236: AB_2732619, HPA077408: AB_2732344" "unprognostic (2.76e-1)" "unprognostic (3.55e-2)" "unprognostic (2.77e-1)" "unprognostic (2.12e-1)" "unprognostic (1.78e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (9.47e-2)" "unprognostic (1.64e-1)" "unprognostic (2.59e-1)" "unprognostic (7.91e-3)" "unprognostic (9.21e-2)" "prognostic favorable (2.78e-11)" "prognostic unfavorable (2.67e-4)" "unprognostic (3.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.57e-2)" 15.4 2.4 11.6 3.2 17.2 4.7 11.2 12.5 11.4 6.2 0.9 7.1 2.0 5.8 3.9 4.5 4.5 6.4 6.3 8.2 10.3 6.7 3.4 9.2 3.4 16.2 13.5 4.5 3.3 3.9 3.6 6.8 14.6 4.2 3.8 7.5 11.0 4.6 3.6 4.5 5.4 8.1 15.1 3.5 5.5 9.0 18.1 2.9 3.7 5.8 4.9 10.0 4.8 23.6 0.0 2.1 25.5 4.6 45.2 19.5 13.5 9.0 3.7 3.7 6.3 4.6 6.0 4.5 11.7 8.7 4.5 4.2 11.0 5.1 6.8 3.3 2.9 5.5 11.2 12.3 3.5 3.1 2.3 14.6 2.1 5.7 14.3 8.9 15.2 4.6 0.8 2.3 6.4 3.1 7.2 0.3 6.6 4.7 2.6 10.3 16.8 2.9 10.0 23.2 5.6 9.5 8.0 3.4 2.5 18.7 0.5 3.4 26.7 12.3 6.2 6.3 4.7 1.3 0.0 11.0 6.2 1.2 3.7 0.0 0.9 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.4 1.5 0.0 0.0 0.1 0.3 1.6 0.0 0.0 0.2 11.6 17.2 12.5 11.4 8.2 10.3 16.2 13.5 14.6 15.1 18.1 23.6 46.2 109.0 29.9 53.2 30.6 9.8 24.7 19.1 7.4 31.3 30.4 15.6 15.3 28.6 32.9 12.9 18.8 10.7 5.7 11.9 17.6 31.3 9.8 61.3 33.1 32.1 25.0 7.2 110.8 27.7 73.4 65.1 13.7 175.5 0.0 23.1 21.4 9.6 12.3 301.2 147.9 7.3 14.2 28.7 43.4 7.3 12.2 37.2 14.2 89.0 21.9 33.4 5.2 86.5 311.1 33.3 13.3 30.5 4.7 67.7 22.5 39.1 42.8 10.4 19.7 43.7 29.2 34.9 66.0 10.2 10.1 18.1 5.7 9.8 9.7 119.9 SETMAR metnase ENSG00000170364 "SET domain and mariner transposase fusion gene" Q53H47 3 4303304-4317567 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Endonuclease, Hydrolase, Methyltransferase, Multifunctional enzyme, Nuclease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA057999 Supported Nucleoli NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoli "HPA057999: AB_2683574" "unprognostic (1.59e-1)" "unprognostic (1.22e-2)" "unprognostic (5.24e-3)" "unprognostic (4.89e-2)" "unprognostic (7.73e-2)" "unprognostic (4.73e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.58e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-1)" "unprognostic (1.19e-3)" "unprognostic (1.19e-1)" "prognostic favorable (6.61e-6)" "unprognostic (5.42e-1)" "unprognostic (3.06e-2)" "unprognostic (1.08e-1)" "unprognostic (1.26e-3)" 6.5 3.7 2.6 2.2 4.3 2.6 8.5 4.2 3.3 8.4 1.9 3.9 2.7 10.3 4.6 4.5 8.5 5.3 3.4 3.0 2.3 6.4 3.3 2.7 2.9 3.6 2.8 12.1 5.1 3.4 3.7 3.7 3.4 7.9 4.3 2.1 5.7 6.1 3.8 4.8 3.1 10.4 2.5 2.8 3.7 4.2 4.0 6.0 7.4 5.1 2.8 5.5 5.2 6.5 3.7 3.2 9.8 2.1 23.1 7.6 9.9 4.1 1.2 3.9 3.7 3.5 2.9 9.9 4.2 2.3 7.2 3.1 8.9 6.1 4.3 6.8 7.6 12.5 6.1 5.6 2.7 5.9 5.1 9.1 4.7 3.0 0.9 3.6 5.7 11.2 8.3 3.6 6.2 5.2 8.9 3.7 9.5 2.4 5.7 10.3 9.6 4.1 3.6 5.1 7.8 11.4 4.9 6.1 5.3 6.2 5.9 3.4 3.8 5.8 8.0 4.9 5.4 4.9 12.3 24.1 2.1 6.7 4.9 0.7 0.4 0.5 0.8 1.2 0.7 1.0 1.0 1.1 0.4 1.3 1.6 2.0 0.0 0.2 0.8 0.6 0.7 0.6 2.6 4.3 4.2 3.3 3.0 2.3 3.6 2.8 3.4 2.5 4.0 6.5 4.8 0.0 5.0 4.9 2.4 2.4 8.0 12.0 10.8 5.8 6.6 13.7 6.6 2.8 10.8 0.0 0.0 25.5 1.9 2.7 13.7 11.2 0.7 3.8 6.3 5.6 3.6 5.5 6.4 13.4 12.1 8.9 5.6 4.4 1.3 13.9 4.2 2.6 5.7 0.0 6.9 2.8 10.2 2.1 1.5 1.9 9.6 2.7 0.0 4.7 4.1 4.6 2.1 7.1 11.7 6.6 4.4 13.2 1.8 4.4 2.0 6.0 6.7 2.8 6.6 7.0 8.1 7.5 6.4 6.0 0.6 16.3 2.8 16.9 5.6 3.6 SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" 29.1 15.6 2.3 1.4 3.0 0.8 60.0 2.7 4.5 619.9 2.1 4.4 1.2 467.1 18.7 2.3 214.0 17.3 22.4 2.5 4.6 4.3 0.6 14.7 7.3 4.0 4.8 79.2 5.0 2.8 20.5 0.2 3.2 16.1 2.6 2.3 6.5 43.9 4.1 1.5 1.4 87.9 4.0 13.9 2.3 16.8 2.7 1.6 14.9 7.0 2.0 37.4 61.0 3.9 0.0 1.8 2.1 0.0 10.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 2.2 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 1.5 0.1 0.3 0.0 3.9 0.5 0.4 0.0 0.7 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.7 0.0 0.8 1.2 0.1 0.4 0.1 0.1 0.2 3.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 2.7 4.5 2.5 4.6 4.0 4.8 3.2 4.0 2.7 3.9 5.5 0.0 1.8 0.3 0.7 1.0 1.5 0.1 0.6 0.0 0.5 2.3 1.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 1.0 22.5 472.1 4.6 0.0 0.0 0.0 0.5 0.3 196.4 0.0 14.1 0.0 102.8 3.3 0.1 0.2 0.0 0.5 0.0 0.0 0.0 4.4 2.8 41.7 7.1 0.0 2.8 0.0 2.7 0.0 17.6 0.2 0.1 0.0 188.4 0.0 2.4 0.0 1.8 0.0 0.3 0.0 30.5 25.3 0.2 0.4 0.1 1.6 0.3 9.2 1.2 0.1 0.5 SGCB "A3b, LGMD2E, SGC" ENSG00000163069 "Sarcoglycan beta" Q16585 4 52020706-52038299 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 105.7" "Cell type enhanced" "Detected in many" "Late spermatids: 203.7" "Cancer enhanced" "Detected in all" "glioma: 56.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 104.7" "Low region specificity" "Detected in all" "HPA011422, HPA058656" Enhanced Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA011422: AB_1856795, HPA058656: AB_2683790" "unprognostic (1.03e-1)" "unprognostic (5.50e-2)" "unprognostic (1.03e-1)" "unprognostic (1.60e-3)" "unprognostic (9.80e-2)" "unprognostic (3.42e-2)" "unprognostic (3.57e-3)" "unprognostic (1.86e-2)" "unprognostic (2.84e-2)" "unprognostic (6.04e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "prognostic favorable (5.53e-6)" "unprognostic (3.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (7.61e-4)" 32.7 21.6 27.1 9.5 30.3 0.5 14.7 28.0 32.2 23.4 21.4 32.9 13.1 28.1 11.1 21.9 20.5 19.5 57.2 25.3 27.7 35.0 10.8 15.2 6.1 29.7 28.4 20.1 6.5 47.0 13.9 24.2 30.3 25.0 16.2 16.6 13.5 27.2 105.7 7.2 14.9 37.3 29.0 11.1 14.0 16.0 28.3 5.6 9.2 81.3 4.5 20.4 15.7 33.4 11.4 13.7 27.8 10.6 104.7 78.5 10.1 62.8 79.9 34.5 36.2 3.7 14.9 3.0 11.8 82.9 53.5 5.5 20.9 23.1 36.7 18.8 7.8 0.2 11.8 6.8 42.8 6.8 3.6 86.8 15.9 29.9 17.3 89.8 46.1 10.7 0.1 0.1 74.5 4.4 15.1 0.1 10.0 4.6 20.4 0.0 14.8 0.2 29.2 3.8 16.2 28.4 39.9 1.9 14.1 31.0 5.2 4.1 47.0 50.8 17.0 24.1 56.6 14.9 20.4 5.5 37.5 2.4 59.7 0.3 1.0 0.0 2.1 0.5 2.1 2.6 2.5 2.3 0.5 2.3 1.7 2.2 0.5 0.3 0.4 1.0 4.2 1.0 27.1 30.3 28.0 32.2 25.3 27.7 29.7 28.4 30.3 29.0 28.3 33.4 38.9 32.1 13.1 15.3 6.6 13.4 25.8 70.2 9.6 22.0 8.6 19.7 88.8 25.8 19.6 12.9 6.2 5.7 2.8 15.6 1.9 28.7 61.1 32.6 48.1 27.2 16.3 0.0 17.3 51.8 49.8 64.6 12.8 29.7 2.5 16.7 36.0 15.7 2.8 28.6 21.2 4.2 8.2 2.1 8.7 203.7 38.8 2.7 26.6 24.4 1.9 23.6 1.0 38.7 38.1 53.8 6.0 91.4 4.6 11.7 32.6 64.6 20.4 16.5 46.0 102.8 59.8 12.2 17.4 8.0 10.5 6.3 7.3 14.2 15.1 13.5 SH3D19 "DKFZp434D0215, EBP, Eve-1, EVE1, Kryn, SH3P19" ENSG00000109686 "SH3 domain containing 19" Q5HYK7 4 151102751-151325605 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 263.9;Oligodendrocytes: 360.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 190.3;ASC TERT1: 161.0;HSkMC: 129.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016424, HPA058562" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA016424: AB_1856814, HPA058562: AB_2683758" "unprognostic (1.09e-1)" "unprognostic (6.14e-2)" "unprognostic (1.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (5.09e-1)" "unprognostic (7.37e-2)" "unprognostic (1.48e-1)" "unprognostic (6.40e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.38e-5)" "unprognostic (7.90e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.64e-2)" 70.8 15.7 9.8 12.8 14.9 0.2 31.5 6.0 9.6 22.5 104.9 44.2 44.4 23.2 10.7 40.8 23.7 63.7 64.1 6.8 11.6 27.2 49.9 36.2 5.1 8.8 10.3 42.9 15.2 19.9 5.0 27.9 8.8 27.1 48.3 12.8 17.3 40.5 17.7 30.0 49.0 41.4 5.1 7.4 22.6 12.4 11.5 3.9 25.1 33.8 7.9 33.3 20.6 18.6 26.3 19.2 12.1 9.5 190.3 161.0 26.0 31.8 34.0 13.9 14.4 24.9 31.6 0.0 12.5 29.9 22.7 19.2 12.8 36.6 13.5 0.1 10.1 0.0 22.2 26.7 46.0 0.1 0.1 129.1 27.6 20.9 32.0 23.9 81.9 0.0 0.0 0.1 36.9 10.9 0.0 0.4 24.3 40.3 27.6 0.0 0.9 0.4 17.3 18.3 0.9 16.3 22.7 23.0 18.5 24.7 7.5 0.1 59.9 43.6 15.6 19.5 12.9 0.1 0.0 0.1 22.6 0.1 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.8 14.9 6.0 9.6 6.8 11.6 8.8 10.3 8.8 5.1 11.5 18.6 36.7 22.4 32.5 8.1 2.9 28.6 14.1 12.3 18.8 6.6 20.5 25.0 88.5 34.3 29.2 16.5 14.6 25.9 5.0 103.5 5.9 11.9 4.4 17.6 38.1 29.1 18.6 7.0 55.8 15.4 20.7 77.9 38.7 13.7 21.5 37.5 21.8 46.4 7.4 6.7 30.0 35.6 10.2 4.6 20.2 6.7 62.1 4.8 26.6 74.0 1.2 20.8 5.2 263.9 360.1 21.3 55.9 48.2 3.2 41.5 88.2 27.2 52.4 11.0 13.1 46.0 26.3 2.9 6.0 16.7 38.5 27.2 5.5 20.3 54.0 41.2 SH3PXD2A "FISH, KIAA0418, SH3MD1" ENSG00000107957 "SH3 and PX domains 2A" Q5TCZ1 10 103594027-103855543 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 86.8;BJ hTERT+: 84.8;fHDF/TERT166: 68.5;HSkMC: 64.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037922, HPA037923" Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA037922: AB_10697088, HPA037923: AB_10672612" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.95e-2)" "unprognostic (3.00e-2)" "unprognostic (1.33e-1)" "unprognostic (1.52e-1)" "unprognostic (1.80e-2)" "unprognostic (1.38e-1)" "unprognostic (4.83e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (5.83e-2)" "unprognostic (3.76e-2)" "prognostic unfavorable (2.04e-6)" "unprognostic (1.25e-1)" "unprognostic (2.59e-1)" "unprognostic (5.78e-3)" "unprognostic (2.62e-2)" 18.9 8.5 49.2 11.5 45.1 1.4 14.5 25.6 38.6 49.0 2.9 27.3 5.7 31.2 7.2 30.3 25.7 17.4 16.9 32.8 32.2 7.0 23.0 17.2 4.7 38.1 40.9 29.5 8.4 1.2 14.0 16.3 39.1 18.5 13.4 17.1 14.1 13.9 19.0 29.4 14.3 26.7 44.8 13.3 13.0 3.0 42.4 6.7 9.2 14.3 5.9 21.5 31.9 64.7 1.3 5.3 13.7 16.5 48.1 86.8 7.3 39.5 84.8 13.1 12.4 0.5 0.4 0.0 7.7 68.5 1.5 13.3 0.8 35.5 11.6 2.3 14.3 16.5 21.8 19.2 31.0 8.2 4.5 64.5 27.2 20.1 43.5 9.8 8.8 17.9 6.1 9.7 16.6 0.5 0.2 8.0 5.8 11.4 2.5 6.8 5.2 1.0 5.5 4.8 10.2 5.5 3.8 0.9 19.9 7.4 0.2 5.8 15.4 11.0 7.6 14.3 17.7 10.9 24.1 0.5 10.7 11.1 42.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 49.2 45.1 25.6 38.6 32.8 32.2 38.1 40.9 39.1 44.8 42.4 64.7 22.6 6.4 45.4 10.1 7.6 91.0 26.4 45.2 56.3 46.1 9.3 13.5 22.9 22.8 37.8 3.7 27.1 12.1 3.4 48.1 0.0 5.3 3.2 7.7 109.9 23.9 37.1 10.5 59.5 0.6 32.0 42.2 12.8 11.5 17.7 21.8 23.9 87.3 13.0 89.2 96.6 74.8 22.4 7.6 34.9 7.3 105.9 7.7 33.8 15.0 19.0 1.7 2.1 5.0 117.2 6.2 27.0 80.5 7.9 32.1 4.1 1.3 21.6 35.7 39.5 32.1 55.6 1.9 3.7 37.5 38.1 4.7 6.8 15.0 22.7 61.1 SH3PXD2B "FLJ20831, KIAA1295" ENSG00000174705 "SH3 and PX domains 2B" A1X283 5 172325000-172454525 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 91.1;Leydig cells: 39.7;Oligodendrocytes: 63.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 95.2;ASC TERT1: 79.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036471 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli fibrillar center" "HPA036471: AB_10670799" "unprognostic (3.32e-1)" "unprognostic (1.95e-2)" "unprognostic (4.84e-1)" "unprognostic (2.96e-1)" "unprognostic (1.84e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (5.38e-3)" "unprognostic (3.11e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.87e-2)" "unprognostic (1.57e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (8.45e-4)" 22.6 25.4 9.2 11.2 12.8 0.1 19.0 12.9 11.5 36.4 9.6 14.0 2.3 32.6 5.4 10.5 17.9 18.9 7.4 9.8 10.7 2.4 2.9 17.6 3.5 14.5 12.8 18.4 9.8 6.6 5.0 8.9 16.0 12.8 5.6 3.6 18.3 13.9 3.5 19.8 11.5 23.2 10.1 6.5 13.1 6.3 13.7 4.2 8.0 3.4 3.4 18.3 18.1 15.4 1.0 14.3 52.3 34.6 95.2 79.9 44.3 8.6 29.7 5.4 10.7 4.0 1.3 0.1 11.5 33.4 16.7 8.1 18.7 9.8 5.3 0.8 3.5 0.1 13.3 2.9 30.6 0.0 36.5 51.5 15.1 22.4 6.4 5.2 37.9 3.8 0.1 0.2 24.1 3.1 0.1 4.6 20.1 8.1 3.3 17.3 8.5 5.1 5.7 1.5 4.6 29.2 6.0 3.8 10.7 16.5 1.4 2.1 40.9 33.4 13.2 20.7 3.8 0.0 0.0 0.2 22.6 2.2 27.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.8 12.9 11.5 9.8 10.7 14.5 12.8 16.0 10.1 13.7 15.4 11.3 0.0 1.1 91.1 0.4 10.1 3.2 13.9 8.6 0.6 6.2 6.5 1.8 5.7 12.0 0.0 0.0 4.5 0.2 1.3 0.0 9.9 0.9 5.5 30.8 6.4 2.4 0.0 5.0 16.0 31.0 29.8 6.1 13.4 0.0 5.8 3.3 1.8 3.1 1.7 11.2 2.1 18.3 28.4 9.4 2.0 39.7 13.6 14.2 13.1 1.3 6.3 0.0 25.1 63.0 21.8 1.0 27.1 0.0 6.9 0.2 1.9 3.8 0.3 13.1 6.0 10.5 0.8 4.2 4.7 8.1 2.2 0.5 22.3 2.7 5.7 SHBG "ABP, MGC126834, MGC138391, TEBG" ENSG00000129214 "Sex hormone binding globulin" P04278 17 7613946-7633382 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 63.4" "Cell type enhanced" "Detected in some" "Early spermatids: 51.6;Late spermatids: 124.5;Proximal enterocytes: 31.1" "Cancer enriched" "Detected in some" 28 "liver cancer: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.4;Hep G2: 3.0;HSkMC: 4.3" "Not detected" "Not detected" "Secreted to blood" NA NA 9100000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.35e-3)" "unprognostic (6.47e-2)" "unprognostic (5.65e-2)" "unprognostic (2.35e-1)" "unprognostic (8.84e-2)" "unprognostic (3.08e-1)" "unprognostic (3.50e-1)" "unprognostic (2.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.32e-3)" "unprognostic (3.58e-3)" "unprognostic (2.21e-1)" "unprognostic (4.49e-2)" "unprognostic (7.83e-3)" "unprognostic (4.35e-1)" "unprognostic (5.50e-3)" "unprognostic (1.06e-1)" 0.7 1.3 1.8 0.0 1.8 0.1 0.4 1.7 2.0 0.7 1.9 0.3 5.3 0.5 0.9 0.2 0.6 0.3 0.6 1.9 1.8 3.5 63.4 0.3 0.1 1.8 1.8 0.7 0.4 0.5 0.7 0.3 1.9 0.5 0.2 0.9 0.2 0.4 0.8 0.1 7.1 0.2 1.7 0.4 0.3 12.4 1.7 0.2 0.8 0.7 0.1 0.3 0.2 1.8 0.1 2.4 2.4 0.3 4.4 2.0 0.1 0.6 0.9 0.9 0.5 0.9 0.3 0.0 0.5 0.8 1.2 0.3 0.1 0.1 0.5 0.1 0.3 0.0 0.6 3.0 1.4 0.0 0.1 4.3 0.3 1.6 0.8 0.8 0.1 0.0 0.2 0.1 0.2 0.5 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.3 0.3 0.1 0.3 1.8 0.0 0.2 0.8 0.4 0.0 0.8 0.4 0.0 0.0 0.2 0.3 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 1.7 2.0 1.9 1.8 1.8 1.8 1.9 1.7 1.7 1.8 0.2 0.0 0.0 0.7 0.5 0.0 0.3 0.1 0.0 0.4 0.5 0.6 0.5 0.0 0.2 0.0 0.0 0.4 0.0 0.2 5.9 0.5 51.6 0.4 0.6 0.1 0.0 0.0 1.0 0.2 0.1 0.4 0.0 0.2 0.0 0.6 1.1 13.8 0.3 0.0 0.9 1.3 2.0 0.8 0.0 124.5 0.9 0.5 0.0 0.0 0.0 2.4 0.0 0.5 0.6 0.1 1.3 0.7 0.0 0.3 31.1 12.8 0.4 1.3 6.6 0.2 0.3 7.2 0.8 0.0 0.0 0.3 0.1 1.1 0.5 0.3 SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 104.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 58.0;Cardiomyocytes: 59.5;Distal enterocytes: 102.4;Paneth cells: 53.0;Proximal enterocytes: 51.6;Undifferentiated cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 88.6;ASC TERT1: 91.3;HSkMC: 98.9;OE19: 97.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" NA NA 2200000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favorable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favorable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" 18.7 17.3 16.8 11.8 21.6 3.7 15.9 26.9 19.8 13.0 38.9 97.8 34.3 7.1 34.3 13.6 19.3 16.7 43.8 16.1 27.1 62.1 43.4 20.6 5.8 25.3 23.7 5.7 17.3 45.3 14.4 11.8 24.7 20.4 104.4 6.2 18.4 15.3 26.7 13.0 35.8 10.4 23.0 9.1 19.0 10.3 24.9 3.7 54.0 33.3 6.7 16.8 7.8 26.3 8.9 14.0 8.0 34.6 88.6 91.3 20.9 16.8 24.0 4.3 2.6 10.9 61.4 5.5 24.2 21.5 9.4 17.3 12.8 18.7 4.2 26.0 3.9 8.6 3.7 11.1 41.8 0.7 7.2 98.9 24.9 11.4 17.3 58.5 30.6 11.0 7.1 37.5 14.8 16.5 0.2 0.6 5.0 97.7 28.5 3.2 0.2 8.4 51.4 12.1 2.4 5.1 46.5 18.6 8.0 24.0 36.8 3.2 34.1 23.6 4.3 26.5 4.0 9.4 7.5 0.7 8.3 4.6 9.8 7.6 2.9 0.1 0.4 2.1 0.3 0.5 1.3 0.6 1.9 0.7 1.7 1.1 0.5 0.2 3.7 0.5 0.6 1.8 16.8 21.6 26.9 19.8 16.1 27.1 25.3 23.7 24.7 23.0 24.9 26.3 4.2 19.2 58.0 11.8 2.4 3.2 6.3 6.7 7.4 6.5 10.1 4.3 59.5 12.8 9.4 36.8 0.0 7.6 0.6 102.4 9.8 15.2 14.0 9.1 9.3 6.9 14.5 5.2 15.0 3.8 8.8 7.5 12.8 14.0 1.3 3.9 8.9 30.0 4.5 5.0 9.1 31.0 4.1 3.5 1.6 12.0 3.1 4.3 3.6 6.5 4.5 1.9 1.0 8.0 6.7 5.2 53.0 1.2 3.9 7.4 51.6 26.2 11.9 1.8 0.0 4.9 7.9 14.8 9.6 12.2 5.3 6.7 2.0 8.9 63.6 7.1 SIDT2 CGI-40 ENSG00000149577 "SID1 transmembrane family member 2" Q8NBJ9 11 117178736-117197445 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 83.5;non-classical monocyte: 151.0" "Lineage enriched" "Detected in all" 7 "monocytes: 151.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052352 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "HPA052352: AB_2681797" "unprognostic (3.83e-1)" "unprognostic (4.30e-2)" "unprognostic (9.92e-2)" "unprognostic (1.03e-1)" "unprognostic (3.01e-2)" "unprognostic (1.69e-1)" "unprognostic (3.34e-1)" "unprognostic (1.84e-1)" "unprognostic (1.39e-1)" "unprognostic (3.12e-1)" "unprognostic (2.67e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (4.18e-5)" "unprognostic (2.74e-2)" "unprognostic (2.20e-1)" "unprognostic (4.36e-2)" "unprognostic (5.22e-3)" 40.2 25.1 23.5 21.2 28.4 12.4 36.3 27.4 27.1 32.8 19.4 28.8 44.2 30.5 16.0 15.1 31.3 18.5 31.8 24.1 23.2 20.6 40.8 36.4 23.4 37.0 29.2 60.2 113.4 13.6 35.7 22.4 33.9 48.6 23.1 14.4 31.5 21.2 25.2 32.7 42.3 20.8 29.7 34.6 75.9 28.5 29.2 10.0 31.7 12.3 20.4 26.2 20.4 48.9 8.7 8.8 10.5 15.4 34.4 30.7 34.8 14.8 19.5 9.3 8.6 25.1 32.8 8.9 23.1 39.1 11.7 9.0 10.2 11.5 7.6 13.2 12.4 6.3 15.8 17.3 17.8 5.3 15.5 38.1 12.8 12.0 12.9 28.6 19.1 11.4 12.0 19.2 22.1 18.2 7.5 6.2 4.9 45.6 6.5 5.6 7.2 25.5 12.2 9.1 3.2 7.9 15.8 38.1 2.6 11.7 30.8 6.3 11.9 12.3 7.9 8.2 3.4 13.6 5.3 9.4 7.1 10.8 9.2 0.3 14.2 0.5 1.9 83.5 1.5 18.3 1.1 1.3 11.5 21.2 1.7 1.3 1.7 1.5 151.0 6.2 1.4 9.6 23.5 28.4 27.4 27.1 24.1 23.2 37.0 29.2 33.9 29.7 29.2 48.9 12.2 6.4 12.3 11.8 24.1 67.7 25.4 4.1 4.0 13.0 11.1 13.0 7.9 4.3 4.5 11.0 6.2 9.2 6.7 16.7 0.0 4.4 7.4 11.6 22.2 12.7 11.4 8.2 7.7 9.6 33.4 19.7 61.2 11.2 2.5 43.5 16.4 25.6 16.9 18.5 8.8 32.9 2.0 54.2 29.3 11.5 13.4 30.6 19.6 7.5 13.6 6.1 7.2 12.1 16.8 8.0 9.4 13.5 6.6 20.5 40.7 1.8 6.0 12.1 19.7 46.1 18.7 5.8 4.8 4.2 42.9 32.3 9.5 38.2 13.5 15.5 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602449-111730855 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 113.3;Excitatory neurons: 217.6;Inhibitory neurons: 132.4;Oligodendrocytes: 191.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC diff: 50.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: AB_1857321, HPA071049: " "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favorable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favorable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 29.7 9.3 9.2 5.3 12.4 3.1 20.7 7.9 11.1 7.6 11.0 7.9 5.9 7.3 5.0 5.9 8.1 10.0 12.3 9.5 14.7 11.4 22.7 11.7 4.4 11.9 11.9 14.9 31.8 21.3 16.6 5.8 10.6 6.7 6.2 30.7 13.8 6.2 33.1 8.9 7.5 5.9 5.5 4.6 17.6 3.0 9.3 5.4 8.7 23.2 4.3 7.7 6.1 11.6 9.2 6.0 10.3 11.1 50.3 14.8 6.1 7.9 11.2 5.9 6.7 20.5 9.6 7.2 10.7 9.2 6.9 12.7 8.2 5.9 7.6 5.4 3.4 7.9 5.2 10.1 10.9 7.7 4.9 14.5 8.6 8.7 11.1 11.7 7.1 7.1 7.4 10.3 9.4 4.3 8.0 7.0 3.5 7.6 5.9 10.6 11.0 8.7 13.1 8.2 4.8 11.3 11.6 4.7 4.5 9.4 11.5 6.2 9.9 12.9 7.7 8.3 10.9 2.9 2.4 14.8 4.2 10.6 8.8 0.3 0.7 0.6 0.7 0.7 0.3 0.4 0.5 0.5 0.6 0.4 0.2 0.4 0.3 0.5 0.6 0.3 0.5 0.5 9.2 12.4 7.9 11.1 9.5 14.7 11.9 11.9 10.6 5.5 9.3 11.6 22.1 19.2 24.8 113.3 14.1 14.7 6.2 5.2 18.2 15.7 10.5 9.9 21.3 27.1 10.0 16.5 66.7 4.4 11.4 15.6 5.9 10.4 16.5 27.7 14.9 18.8 18.0 12.4 217.6 7.9 4.6 20.1 27.5 45.3 9.5 24.3 9.3 38.7 5.4 32.0 132.4 11.3 4.1 12.4 16.9 14.1 11.5 13.3 19.6 73.1 6.0 14.5 4.1 86.0 191.9 8.4 10.3 14.7 8.9 6.9 8.3 23.1 13.4 60.9 0.0 19.1 19.0 3.9 6.4 10.3 11.9 5.2 12.6 5.0 11.5 7.1 SIRT2 SIR2L ENSG00000068903 "Sirtuin 2" Q8IXJ6 19 38878555-38899862 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Meiosis, Mitosis, Neurogenesis, Transcription, Transcription regulation" Transferase "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 302.1;tongue: 218.2" "Cell type enhanced" "Detected in all" "Early spermatids: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004573, HPA011165" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Cytosol" Nucleoplasm "CAB004573: AB_2188600, HPA011165: AB_1856900" "unprognostic (2.15e-2)" "unprognostic (2.24e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (7.20e-7)" "unprognostic (3.75e-3)" "unprognostic (1.28e-2)" "unprognostic (2.85e-2)" "unprognostic (2.44e-3)" "unprognostic (2.73e-1)" "unprognostic (4.83e-2)" "unprognostic (2.97e-3)" "unprognostic (1.02e-1)" "unprognostic (1.90e-1)" "unprognostic (3.60e-2)" "unprognostic (1.19e-1)" "unprognostic (8.73e-2)" "unprognostic (1.70e-1)" 43.2 44.0 101.6 11.5 137.5 17.4 39.7 141.1 123.0 41.5 79.4 49.2 12.6 37.2 10.4 42.5 37.2 15.0 76.9 100.7 111.2 35.9 51.5 38.2 13.7 151.0 129.6 49.0 33.4 18.2 31.2 10.5 144.7 32.7 10.2 11.9 41.5 14.9 302.1 48.8 32.4 18.3 121.3 40.1 41.4 43.5 127.6 13.1 34.5 218.2 13.0 41.3 37.8 173.5 16.1 9.8 8.4 20.6 46.7 31.8 5.8 11.3 20.2 17.8 22.7 17.1 10.2 5.4 23.7 21.3 13.2 8.3 14.6 25.1 10.9 25.2 15.6 10.1 10.9 10.9 33.0 7.0 22.4 33.5 29.7 14.4 16.9 21.4 31.9 17.7 10.1 42.0 28.2 8.9 15.4 6.2 1.2 27.6 13.6 19.9 22.8 15.3 14.8 14.9 20.7 9.0 12.9 17.8 13.0 7.0 8.0 19.2 28.9 24.0 5.1 37.2 17.0 16.9 8.8 12.6 18.1 19.0 22.0 48.9 54.7 59.8 44.9 69.1 28.5 24.9 21.9 31.0 42.9 28.9 14.3 23.6 42.7 36.5 56.7 44.0 33.1 51.9 101.6 137.5 141.1 123.0 100.7 111.2 151.0 129.6 144.7 121.3 127.6 173.5 39.5 16.0 19.4 26.1 21.0 51.6 30.3 35.1 35.3 29.7 28.8 29.7 42.1 14.3 27.2 12.9 35.5 36.5 90.8 28.4 37.2 29.0 173.0 24.7 15.4 31.1 17.5 27.1 31.2 17.6 15.2 30.3 44.9 26.5 25.4 29.5 28.5 19.7 66.3 30.3 27.2 24.1 97.6 38.3 51.7 74.8 31.1 37.1 46.2 11.2 20.0 22.6 85.5 76.4 110.8 26.5 23.9 41.0 39.7 14.9 54.0 38.8 30.1 28.2 19.7 113.5 27.9 15.3 7.2 30.1 60.1 42.3 45.8 31.3 18.2 21.5 SIRT3 SIR2L3 ENSG00000142082 "Sirtuin 3" Q9NTG7 11 215030-236931 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026809, CAB037142" Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "CAB037142: AB_1079982, HPA026809: AB_10601160" "unprognostic (1.76e-2)" "unprognostic (2.69e-1)" "unprognostic (2.04e-1)" "prognostic favorable (8.51e-5)" "unprognostic (1.52e-3)" "unprognostic (2.65e-1)" "unprognostic (3.45e-2)" "unprognostic (5.52e-2)" "unprognostic (8.64e-2)" "unprognostic (1.31e-1)" "prognostic favorable (4.45e-4)" "unprognostic (2.06e-1)" "prognostic favorable (4.85e-9)" "unprognostic (1.04e-1)" "unprognostic (5.53e-2)" "unprognostic (3.45e-1)" "unprognostic (3.75e-2)" 11.1 13.8 24.5 10.4 28.8 11.8 18.6 19.7 28.8 14.3 26.1 13.9 13.3 12.6 40.1 9.9 14.4 7.6 24.4 25.1 20.8 17.2 25.8 10.3 13.8 19.0 20.4 18.3 18.0 11.2 28.0 5.8 18.4 16.7 14.2 26.8 12.6 12.4 27.3 20.2 14.6 9.7 19.0 14.7 13.5 25.2 21.6 6.8 15.7 19.9 14.9 11.5 11.1 24.0 9.7 11.1 16.7 17.7 19.1 24.1 8.0 13.6 11.0 10.1 7.9 11.5 22.8 5.9 6.2 8.5 9.8 18.6 8.2 7.4 9.8 11.2 12.7 7.4 15.7 12.6 8.4 9.7 17.3 17.8 14.1 10.2 10.9 17.3 6.7 11.1 15.3 11.0 4.6 10.8 4.0 15.0 7.5 8.5 13.2 10.8 13.2 9.8 10.2 6.6 9.3 7.5 11.5 16.7 6.4 10.8 11.9 2.2 9.3 11.4 5.4 3.2 4.1 19.4 17.3 8.4 12.4 7.7 5.9 0.1 3.1 3.1 3.6 2.5 3.8 5.3 3.3 4.1 2.8 4.3 6.0 4.9 3.1 8.1 6.6 4.8 4.0 2.7 24.5 28.8 19.7 28.8 25.1 20.8 19.0 20.4 18.4 19.0 21.6 24.0 6.0 3.2 6.5 17.0 10.4 5.0 7.0 13.1 12.5 7.4 16.0 15.5 23.4 14.3 7.4 5.5 8.4 12.6 7.2 7.2 33.2 7.5 22.0 7.4 5.8 6.7 6.0 14.3 19.2 5.8 10.3 8.6 11.7 4.6 10.2 8.4 7.5 18.3 8.8 10.1 18.3 8.1 10.2 5.5 3.3 21.0 9.0 6.4 10.6 8.4 3.5 13.5 5.2 9.0 11.6 5.1 9.3 9.1 14.6 5.5 14.3 18.9 9.0 9.5 0.0 7.3 6.5 25.5 9.6 9.9 4.1 6.8 8.4 14.2 11.2 4.0 SIRT4 SIR2L4 ENSG00000089163 "Sirtuin 4" Q9Y6E7 12 120302316-120313249 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage" Transferase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029691, HPA029692" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA029691: AB_10600118, HPA029692: AB_10611520" "unprognostic (2.62e-2)" "unprognostic (7.08e-2)" "unprognostic (4.46e-3)" "unprognostic (1.09e-1)" "unprognostic (1.51e-1)" "unprognostic (2.35e-2)" "unprognostic (2.37e-2)" "unprognostic (4.53e-2)" "unprognostic (1.25e-1)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (1.54e-1)" "prognostic favorable (1.75e-4)" "unprognostic (4.97e-2)" "unprognostic (2.11e-1)" "unprognostic (9.74e-3)" "unprognostic (2.31e-1)" 0.9 3.9 2.9 1.0 2.6 0.3 1.1 3.7 3.2 1.9 3.1 2.8 3.5 2.0 0.8 1.4 1.4 1.2 4.5 2.8 2.5 3.2 3.9 1.6 1.4 2.8 2.5 2.5 1.9 2.8 0.9 0.9 2.8 1.3 1.0 3.7 3.0 1.5 9.8 3.1 1.6 1.8 2.3 1.5 2.2 6.2 2.6 2.2 1.8 7.2 1.0 1.5 1.3 2.9 0.6 1.4 1.9 0.9 5.9 1.9 0.9 1.4 1.6 1.1 2.9 1.5 0.9 1.0 1.6 0.8 1.5 0.3 1.9 0.7 1.9 2.0 2.5 0.0 0.3 1.2 1.4 1.1 0.5 1.7 1.6 0.6 0.4 3.2 1.5 2.8 2.0 0.1 1.7 0.8 1.9 1.6 1.1 0.4 1.1 2.3 3.5 1.0 1.6 0.1 1.9 1.6 1.0 0.1 0.9 3.2 2.3 0.4 0.2 0.9 1.5 0.8 0.3 2.3 2.1 0.3 0.9 0.6 1.4 6.7 1.4 0.2 3.8 0.6 5.8 2.7 2.5 3.1 0.8 3.5 4.4 3.9 0.0 2.5 0.1 3.8 0.2 1.2 2.9 2.6 3.7 3.2 2.8 2.5 2.8 2.5 2.8 2.3 2.6 2.9 1.3 6.4 2.0 3.6 2.3 0.4 0.8 0.6 1.2 0.8 1.3 2.4 4.5 0.0 2.4 0.0 2.1 1.2 2.2 0.1 7.9 1.7 29.7 1.2 1.5 0.4 0.0 0.8 5.5 1.1 1.0 1.2 1.1 1.0 0.0 2.8 0.4 1.4 0.7 5.0 7.0 0.9 0.0 0.0 0.6 4.0 1.2 0.4 0.0 1.0 0.0 1.8 0.0 3.5 2.5 0.6 2.9 2.2 0.7 0.4 4.5 6.1 0.4 2.9 0.0 1.1 1.5 6.3 0.9 1.5 1.4 0.8 1.3 6.3 0.9 0.1 SKI ENSG00000157933 "SKI proto-oncogene" P12755 1 2228319-2310213 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Craniosynostosis, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010449, HPA066567" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "CAB010449: AB_2187342, HPA066567: AB_2685692" "unprognostic (3.99e-2)" "unprognostic (3.81e-2)" "unprognostic (1.44e-1)" "unprognostic (5.42e-2)" "unprognostic (4.66e-2)" "unprognostic (7.32e-2)" "unprognostic (1.88e-1)" "unprognostic (9.14e-2)" "unprognostic (1.08e-1)" "unprognostic (4.76e-2)" "unprognostic (4.94e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-3)" "unprognostic (1.88e-1)" "unprognostic (7.82e-2)" "unprognostic (9.69e-2)" "unprognostic (5.24e-3)" 38.3 14.3 22.0 14.1 20.9 11.5 31.5 59.5 24.2 37.5 3.4 34.6 9.3 42.0 8.3 23.5 34.1 14.6 34.4 24.1 11.0 23.6 24.3 33.9 11.6 20.1 16.9 36.4 13.1 7.3 23.0 13.9 17.2 26.8 7.0 5.1 25.2 19.8 22.1 38.6 24.1 16.8 17.1 22.9 22.6 13.2 19.4 8.7 25.4 11.7 10.2 30.8 29.2 15.7 18.3 10.4 24.5 23.9 40.0 23.8 16.1 26.7 14.8 16.3 11.9 15.8 13.7 11.5 19.5 34.4 6.8 21.0 13.8 21.6 15.0 12.7 30.0 29.0 16.4 22.5 26.7 16.5 29.8 25.8 11.8 24.5 18.2 30.0 20.2 4.8 16.6 8.6 20.2 11.6 2.0 18.1 24.8 12.0 19.8 9.1 15.5 9.6 13.9 7.0 35.0 22.9 26.0 22.9 26.7 15.6 7.7 20.9 36.9 27.7 17.5 39.6 21.1 6.7 5.2 10.5 14.8 28.2 11.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 22.0 20.9 59.5 24.2 24.1 11.0 20.1 16.9 17.2 17.1 19.4 15.7 44.2 9.6 12.6 18.9 18.8 47.0 13.1 7.0 32.5 8.9 20.3 25.8 12.7 11.5 6.7 7.3 0.0 7.3 32.2 7.3 1.9 8.2 0.8 10.1 28.9 34.3 6.0 14.7 22.6 6.9 15.5 35.5 9.7 18.5 13.3 6.4 33.9 23.0 13.7 11.8 24.1 14.3 0.0 16.4 29.5 5.0 49.7 28.9 16.0 48.7 9.4 11.1 12.3 11.6 11.4 13.0 9.4 55.3 16.9 14.9 8.1 6.0 4.0 4.4 46.0 36.2 37.3 4.7 12.8 32.2 45.0 16.3 33.4 6.7 10.7 11.4 SLC16A12 MCT12 ENSG00000152779 "Solute carrier family 16 member 12" Q6ZSM3 10 89430299-89556641 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" Cataract "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 92.2;epididymis: 51.8;kidney: 85.2;pancreas: 25.3" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 18.1;Leydig cells: 27.1;Peritubular cells: 26.7;Proximal tubular cells: 69.2" "Cancer enriched" "Detected in many" 10 "renal cancer: 18.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC TERT1: 23.0;HSkMC: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037587 Approved Mitochondria NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA037587: AB_2732475" "unprognostic (5.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.79e-2)" "unprognostic (2.28e-2)" "unprognostic (3.51e-1)" "unprognostic (5.35e-2)" "unprognostic (2.45e-1)" "unprognostic (1.32e-1)" "unprognostic (1.78e-2)" "unprognostic (2.42e-1)" "unprognostic (9.60e-2)" "unprognostic (2.31e-1)" "prognostic favorable (4.50e-12)" "unprognostic (3.84e-2)" "unprognostic (7.91e-2)" "unprognostic (8.29e-2)" "unprognostic (1.84e-3)" 1.8 2.5 0.8 0.1 1.1 0.0 1.9 1.0 2.7 9.2 92.2 0.8 0.1 1.4 51.8 0.3 4.1 0.1 4.9 2.9 0.3 85.2 2.0 2.5 0.1 0.5 1.6 1.3 25.3 0.1 3.4 11.6 0.6 0.6 0.2 0.0 0.4 14.1 1.6 0.5 0.3 0.3 1.2 0.0 1.0 3.3 1.0 0.4 6.2 2.5 0.0 0.4 0.7 0.6 0.2 0.0 0.0 0.0 3.0 23.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 1.2 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.5 0.0 3.7 0.0 0.0 8.2 0.2 1.2 1.5 2.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 2.8 0.0 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 1.1 1.0 2.7 2.9 0.3 0.5 1.6 0.6 1.2 1.0 0.6 0.8 3.2 3.9 3.3 0.6 0.0 2.2 0.1 0.0 0.1 4.6 0.1 3.3 1.5 2.9 14.7 0.0 16.4 0.1 0.0 15.6 0.0 8.3 11.5 0.8 1.3 18.1 0.0 0.3 4.1 1.1 2.2 0.0 1.0 1.3 0.0 0.4 2.2 1.2 3.3 0.4 0.2 0.0 0.0 0.9 4.8 27.1 1.0 0.0 11.2 0.1 0.0 0.0 0.0 0.4 2.1 0.1 26.7 0.0 0.7 0.0 69.2 6.2 0.6 13.1 3.4 7.8 0.2 0.5 0.0 0.3 9.0 0.9 0.1 0.0 1.8 SLC17A5 "AST, ISSD, NSD, SD, SIALIN, SIASD, SLD" ENSG00000119899 "Solute carrier family 17 member 5" Q9NRA2 6 73593379-73653992 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "parathyroid gland: 310.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 99.9;ASC TERT1: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044479 Supported "Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cytosol" "HPA044479: " "unprognostic (6.48e-3)" "unprognostic (7.95e-3)" "unprognostic (9.23e-2)" "unprognostic (1.45e-2)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.59e-3)" "unprognostic (4.44e-2)" "unprognostic (4.18e-2)" "unprognostic (2.60e-1)" "unprognostic (3.14e-2)" "unprognostic (8.29e-2)" "unprognostic (4.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "prognostic favorable (3.52e-4)" "unprognostic (1.09e-1)" 10.4 10.5 5.9 6.4 6.0 6.8 13.8 6.2 7.0 10.7 5.9 20.4 16.4 9.4 44.6 8.4 5.3 10.4 8.5 6.5 8.5 31.9 17.6 13.2 5.3 6.5 7.0 4.0 11.6 310.5 9.9 21.7 7.8 16.8 22.1 18.3 30.3 14.7 5.4 7.1 21.1 10.6 5.7 7.0 14.4 6.1 7.1 4.5 43.5 6.2 5.6 12.6 6.3 7.6 7.4 9.9 9.7 15.6 99.9 74.2 12.8 23.8 59.4 6.3 22.0 6.6 17.6 6.8 11.2 32.9 14.8 12.6 13.7 5.9 11.2 4.8 15.5 2.8 5.1 15.4 19.4 5.6 10.8 34.2 8.8 14.2 9.7 26.4 16.2 9.0 7.1 7.2 22.3 4.9 2.3 3.3 7.1 30.9 5.7 5.0 12.1 28.5 16.0 20.2 3.8 6.7 4.8 14.0 14.4 14.0 6.3 34.1 23.5 3.0 2.8 12.1 5.7 20.4 30.6 1.9 10.5 11.6 9.0 13.3 7.9 3.3 6.0 7.4 5.8 3.9 6.6 5.8 7.6 2.4 5.4 6.0 5.7 8.9 4.8 5.5 6.6 4.9 5.9 6.0 6.2 7.0 6.5 8.5 6.5 7.0 7.8 5.7 7.1 7.6 8.8 22.4 20.7 16.3 8.2 9.6 13.2 13.7 5.7 8.2 22.6 5.5 6.8 18.6 17.4 51.5 29.2 19.4 11.0 46.4 3.9 14.2 36.6 16.6 7.8 13.8 12.1 3.8 47.7 13.7 13.5 25.8 14.8 19.6 14.5 3.2 23.9 32.9 64.6 0.0 46.8 47.7 20.3 24.8 22.7 48.3 7.5 25.4 10.6 14.0 11.2 8.3 13.4 17.6 16.3 19.2 17.5 11.3 20.6 29.1 23.9 36.3 21.5 28.9 0.0 10.5 9.1 8.4 3.6 10.2 11.2 22.8 11.0 2.9 19.2 30.7 SLC25A12 Aralar ENSG00000115840 "Solute carrier family 25 member 12" O75746 2 171783405-171999859 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 97.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.7;Excitatory neurons: 148.5;Inhibitory neurons: 175.2;Oligodendrocyte precursor cells: 111.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035333, HPA035334" Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA 9100 "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" Cytosol "HPA035333: AB_10603028, HPA035334: AB_2674577" "unprognostic (3.24e-2)" "unprognostic (2.52e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (2.65e-2)" "unprognostic (7.27e-2)" "unprognostic (4.21e-3)" "unprognostic (5.23e-2)" "unprognostic (1.39e-1)" "unprognostic (4.96e-2)" "unprognostic (7.76e-2)" "unprognostic (1.13e-1)" "prognostic favorable (2.91e-8)" "unprognostic (8.64e-3)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (2.70e-1)" 11.1 11.5 8.5 4.0 9.0 2.8 11.6 9.3 12.3 11.5 6.1 25.2 2.2 13.4 4.3 12.7 11.7 3.7 62.7 8.9 9.0 13.4 1.8 7.1 4.4 6.9 6.7 14.5 3.9 12.0 17.1 3.2 6.8 13.7 6.1 15.8 16.8 9.5 97.0 14.5 10.7 8.5 5.8 8.9 16.4 6.1 7.4 5.6 15.1 51.1 5.2 16.2 12.4 8.4 4.9 3.0 4.2 8.0 9.5 11.7 0.0 5.3 11.2 7.7 7.3 2.2 3.2 14.5 2.6 7.5 4.3 4.3 7.9 8.5 10.7 6.3 10.4 6.9 4.4 5.5 3.8 14.8 4.9 12.6 7.0 11.0 2.3 4.1 8.0 7.0 5.0 5.2 4.4 3.2 9.7 6.5 3.0 3.8 4.7 9.6 4.7 7.4 8.0 4.5 5.1 1.6 2.6 8.5 4.0 2.5 2.8 3.1 6.4 6.2 2.0 6.0 3.2 8.8 4.2 13.6 9.1 7.5 2.9 0.0 0.4 0.1 1.0 0.4 0.8 0.7 0.5 0.9 0.4 0.5 0.9 1.5 0.0 0.9 0.7 0.1 0.7 0.4 8.5 9.0 9.3 12.3 8.9 9.0 6.9 6.7 6.8 5.8 7.4 8.4 9.8 0.0 9.8 71.2 11.3 6.9 10.2 13.2 19.9 25.5 9.3 11.8 97.7 0.0 18.4 18.4 25.0 7.5 10.7 11.6 19.6 1.7 3.2 5.0 10.3 8.7 14.4 6.9 148.5 3.3 1.8 15.1 12.8 6.1 10.8 7.3 7.9 0.6 4.5 37.0 175.2 6.1 16.2 8.4 5.4 2.1 12.5 7.2 16.0 25.3 9.7 19.8 5.2 111.6 44.1 2.0 4.7 24.5 19.5 4.6 4.1 13.2 11.2 25.5 13.1 12.5 16.6 7.8 9.1 16.8 7.7 1.2 15.0 11.0 7.6 8.3 SLC25A51 "CG7943, MCART1, MGC14836" ENSG00000122696 "Solute carrier family 25 member 51" Q9H1U9 9 37879400-37904353 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 93.6;Late spermatids: 169.6;Spermatocytes: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (5.46e-2)" "unprognostic (2.28e-1)" "unprognostic (2.67e-2)" "unprognostic (5.63e-2)" "unprognostic (1.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (6.87e-2)" "unprognostic (1.04e-1)" "unprognostic (7.98e-3)" "unprognostic (1.26e-3)" "unprognostic (5.37e-2)" "prognostic favorable (1.52e-4)" "unprognostic (8.27e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (2.08e-2)" 9.0 3.1 3.1 5.0 3.5 12.0 4.1 3.4 4.4 5.4 2.3 4.5 7.5 4.1 4.7 5.6 3.4 5.0 4.5 3.7 4.1 6.3 3.1 5.2 5.7 3.4 3.3 3.8 5.9 8.3 4.1 4.7 4.0 3.5 4.1 4.8 4.7 3.7 6.1 5.7 6.0 5.8 2.6 5.7 4.3 8.0 3.1 5.6 4.6 7.4 6.5 4.3 3.5 4.4 12.4 10.1 7.3 11.6 34.4 15.2 7.4 10.6 10.7 8.8 12.6 13.0 5.2 26.2 5.9 24.2 12.5 6.1 19.6 14.5 16.5 18.0 6.1 8.0 27.5 18.0 19.1 12.5 11.1 15.3 16.7 13.4 16.6 13.6 16.1 24.4 17.9 20.2 19.1 7.3 15.2 3.2 9.2 12.7 7.1 10.6 9.9 16.1 8.7 8.9 15.2 10.0 8.3 10.1 6.0 12.2 5.4 13.7 17.3 14.7 17.4 7.2 12.8 7.7 17.5 17.5 19.4 9.3 12.3 16.7 1.5 2.8 1.6 3.1 2.7 2.6 1.7 2.3 1.1 1.5 1.6 1.8 1.3 1.9 1.3 0.5 2.7 0.9 3.1 3.5 3.4 4.4 3.7 4.1 3.4 3.3 4.0 2.6 3.1 4.4 4.3 9.6 1.1 13.4 9.3 4.7 5.8 7.6 8.6 4.0 5.1 3.8 6.3 5.7 4.6 1.8 4.2 3.7 7.6 3.8 17.6 9.5 93.6 2.5 5.3 4.3 3.6 6.9 22.0 7.2 14.1 5.2 8.2 5.1 3.8 3.4 3.9 3.6 11.7 1.7 21.3 5.8 0.0 5.7 4.7 169.6 3.7 8.8 1.8 19.7 8.4 5.3 3.1 16.1 22.1 7.3 7.2 4.1 14.3 3.8 17.4 16.8 2.2 3.7 0.0 4.3 4.5 44.0 10.2 11.7 5.8 4.0 6.5 4.8 3.6 3.8 SLC27A3 "ACSVL3, FATP3, MGC4365" ENSG00000143554 "Solute carrier family 27 member 3" Q5K4L6 1 153774354-153780157 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 7.4;granulocytes: 12.6;monocytes: 11.1" "Cell line enhanced" "Detected in many" "ASC diff: 53.3;MCF7: 30.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA006935, HPA067508" Enhanced Enhanced "Endoplasmic reticulum" Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA006935: AB_1080003, HPA067508: AB_2685857" "unprognostic (1.88e-1)" "unprognostic (2.66e-2)" "unprognostic (1.34e-1)" "unprognostic (3.57e-2)" "unprognostic (2.70e-2)" "unprognostic (4.85e-2)" "unprognostic (6.08e-2)" "unprognostic (3.18e-2)" "unprognostic (4.22e-2)" "unprognostic (3.39e-2)" "prognostic favorable (5.23e-4)" "unprognostic (4.67e-2)" "prognostic unfavorable (6.33e-4)" "unprognostic (1.95e-1)" "unprognostic (4.41e-1)" "unprognostic (2.59e-1)" "unprognostic (2.08e-1)" 18.9 5.0 4.1 3.3 4.1 2.5 17.7 3.3 5.7 8.3 4.6 8.8 2.4 6.3 37.7 6.1 9.8 5.7 8.3 4.0 4.1 11.1 20.4 19.0 4.7 4.2 5.6 9.2 8.0 9.2 9.9 6.4 3.9 7.1 5.0 0.6 5.1 8.0 3.1 12.3 7.7 5.8 3.6 8.6 19.3 12.2 3.9 2.3 9.4 3.7 2.8 7.4 9.5 4.0 2.6 0.5 3.1 1.5 53.3 10.8 0.8 0.5 3.9 1.2 1.0 1.8 1.8 1.1 1.6 2.4 0.6 9.3 3.0 1.5 0.7 0.4 1.4 1.5 2.8 1.9 6.7 1.4 5.8 5.5 6.6 0.3 1.4 1.1 7.0 0.3 0.8 1.4 0.3 30.8 0.3 8.1 3.4 12.2 1.4 8.6 0.6 0.9 1.5 0.9 2.7 1.7 0.6 9.6 3.0 4.1 3.9 5.5 0.0 1.5 2.8 3.3 0.1 2.4 2.4 0.3 2.5 5.7 1.2 9.5 10.7 12.6 2.1 8.8 1.3 0.6 0.6 2.1 7.4 0.7 0.2 0.6 0.9 2.5 11.1 1.0 0.2 3.4 4.1 4.1 3.3 5.7 4.0 4.1 4.2 5.6 3.9 3.6 3.9 4.0 47.3 19.2 51.8 6.5 5.5 11.7 12.6 9.0 8.0 0.9 4.4 11.3 4.6 34.3 10.1 3.7 0.0 27.2 20.7 4.2 0.0 4.3 0.6 5.1 12.1 42.4 4.2 0.4 2.6 7.3 13.0 20.3 16.8 7.9 25.4 1.8 106.1 30.6 33.2 1.7 2.6 23.7 6.1 31.7 39.8 3.2 19.0 21.3 23.2 1.9 44.6 2.0 35.0 0.5 1.6 3.1 42.3 14.3 7.9 3.4 2.5 3.6 6.6 1.0 6.6 3.4 15.7 1.7 2.9 5.5 7.7 8.8 13.0 5.2 10.7 7.0 SLC30A4 ZNT4 ENSG00000104154 "Solute carrier family 30 member 4" O14863 15 45479606-45522755 "Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "prostate: 39.9" "Cell type enhanced" "Detected in many" "Early spermatids: 76.3;Late spermatids: 78.5;Prostatic glandular cells: 39.2;Spermatocytes: 52.1" "Cancer enriched" "Detected in all" 20 "prostate cancer: 34.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.64e-2)" "unprognostic (1.40e-1)" "unprognostic (3.71e-1)" "unprognostic (9.49e-2)" "unprognostic (1.98e-1)" "unprognostic (3.29e-2)" "unprognostic (6.15e-2)" "unprognostic (9.74e-2)" "unprognostic (7.38e-3)" "unprognostic (1.51e-1)" "prognostic favorable (6.02e-4)" "unprognostic (2.66e-2)" "unprognostic (4.72e-3)" "unprognostic (1.29e-2)" "unprognostic (9.83e-2)" "unprognostic (8.28e-3)" "unprognostic (2.01e-3)" 2.8 1.8 2.6 1.9 9.3 0.8 1.9 3.1 4.5 2.8 1.5 3.2 7.0 2.9 2.7 4.2 2.0 2.0 1.9 2.7 2.4 4.2 2.5 1.8 2.7 2.2 2.6 2.5 1.8 4.1 1.5 3.4 2.4 39.9 3.1 3.7 1.3 2.2 1.7 2.5 8.5 3.4 2.1 3.0 2.0 6.3 3.8 1.0 4.7 1.9 3.4 1.8 2.5 7.3 1.8 2.1 0.6 4.7 8.3 5.8 0.4 4.5 4.1 2.7 3.8 0.3 1.5 6.9 1.5 4.7 1.1 1.2 2.0 2.1 2.5 1.7 1.8 0.1 2.0 0.1 5.3 0.1 3.5 4.9 3.4 3.6 0.9 4.2 3.2 3.2 1.0 3.8 5.1 0.8 2.4 0.3 0.1 0.4 0.4 3.6 4.0 1.1 2.2 0.4 1.5 2.3 3.0 3.4 0.8 0.6 2.9 0.2 6.1 4.0 2.3 4.9 1.5 7.0 5.5 1.7 1.7 0.2 3.1 1.3 0.1 0.1 2.2 0.1 2.1 2.0 1.5 1.3 0.2 3.5 1.5 2.1 0.5 1.3 0.1 0.2 0.2 0.7 2.6 9.3 3.1 4.5 2.7 2.4 2.2 2.6 2.4 2.1 3.8 7.3 6.7 3.2 3.9 5.5 6.6 6.8 2.2 1.1 6.8 3.2 2.8 2.2 3.1 0.0 0.1 1.8 16.7 1.0 3.9 15.2 0.0 1.3 76.3 5.0 8.4 6.9 1.2 0.4 14.0 1.1 0.9 7.5 4.6 12.7 1.3 1.9 11.0 3.3 3.1 13.5 9.4 7.1 0.0 1.6 30.8 78.5 6.2 4.4 7.2 9.4 5.3 4.3 10.3 6.0 28.8 0.7 22.0 8.2 6.0 39.2 32.4 12.5 0.7 2.2 6.6 6.2 5.2 52.1 19.9 7.4 6.5 0.3 5.4 3.6 5.1 1.7 SLC38A6 NAT-1 ENSG00000139974 "Solute carrier family 38 member 6" Q8IZM9 14 60981114-61083733 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 178.2;Excitatory neurons: 98.8;Hofbauer cells: 100.3;Inhibitory neurons: 77.4;Late spermatids: 124.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018508 Approved Approved "Plasma membrane,Cell Junctions,Microtubules" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Cell Junctions" "Plasma membrane, Microtubules" "HPA018508: AB_2190518" "unprognostic (7.08e-2)" "unprognostic (4.14e-2)" "unprognostic (1.75e-1)" "unprognostic (3.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (9.47e-6)" "unprognostic (9.89e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-2)" "unprognostic (2.20e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (1.37e-5)" "unprognostic (1.73e-1)" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.90e-1)" 7.6 9.1 6.0 4.7 6.6 2.9 7.4 6.1 9.5 7.3 8.9 4.8 3.1 5.1 13.2 3.3 5.6 9.9 3.7 6.9 6.5 12.0 6.3 8.6 7.8 5.4 6.0 5.8 3.4 21.3 7.2 9.6 6.0 5.1 6.6 7.5 5.9 3.9 2.1 2.9 3.5 5.3 5.0 6.6 3.8 5.0 7.4 5.0 6.3 3.0 4.8 7.0 5.0 6.7 16.2 21.5 6.8 12.3 68.7 25.3 4.9 11.6 34.5 10.7 10.2 5.4 41.0 4.0 19.2 10.6 22.5 13.5 6.8 11.9 9.8 6.0 3.2 6.7 8.6 14.2 22.7 3.7 12.1 19.9 4.9 10.5 12.2 43.2 14.3 6.8 9.3 8.4 37.5 9.2 6.6 8.4 4.0 9.5 14.3 1.6 20.1 11.9 30.7 8.5 3.3 3.0 9.9 7.0 19.1 9.3 10.4 5.8 15.6 16.4 7.1 20.0 6.5 1.6 4.9 1.6 34.0 3.0 13.1 0.0 6.6 0.1 1.7 7.1 2.2 2.2 3.1 2.4 3.6 2.0 2.7 3.4 0.2 0.8 4.5 4.4 4.5 2.8 6.0 6.6 6.1 9.5 6.9 6.5 5.4 6.0 6.0 5.0 7.4 6.7 6.8 22.4 6.7 31.6 6.0 5.2 11.4 14.6 8.0 19.7 7.2 7.5 4.3 7.2 10.0 5.5 22.9 5.6 4.9 2.6 1.9 5.3 178.2 13.0 11.0 7.2 4.2 3.4 98.8 2.8 9.4 11.2 5.1 6.2 6.3 7.3 4.2 4.6 100.3 5.0 77.4 3.1 6.1 24.8 10.0 124.4 10.8 26.2 5.4 20.6 6.4 11.7 2.1 54.3 30.8 7.4 1.9 6.0 5.8 6.6 3.3 23.1 40.4 24.9 0.0 12.3 9.1 16.6 11.5 6.4 2.8 6.7 7.8 5.0 2.8 6.9 SLC44A1 "CD92, CDW92, CHTL1, CTL1" ENSG00000070214 "Solute carrier family 44 member 1" Q8WWI5 9 105244622-105439171 "CD markers, Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 284.9" "Cell type enriched" "Detected in all" 8 "Oligodendrocytes: 2444.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 285.9;ASC TERT1: 224.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064714, HPA074007" Enhanced Supported Nucleoplasm,Mitochondria NA NA 99000 "Cluster 24: B-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria Nucleoplasm "HPA064714: AB_2685334, HPA074007: " "unprognostic (3.49e-1)" "unprognostic (2.25e-1)" "unprognostic (1.27e-1)" "unprognostic (6.54e-3)" "unprognostic (4.77e-2)" "unprognostic (1.74e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.49e-4)" "unprognostic (2.48e-1)" "unprognostic (1.95e-1)" "unprognostic (1.64e-3)" "unprognostic (6.20e-2)" "prognostic favorable (1.85e-4)" "unprognostic (2.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.33e-1)" "unprognostic (2.07e-2)" 16.9 13.3 112.9 12.9 204.4 11.4 26.2 166.7 138.7 16.7 79.4 50.2 22.6 15.9 32.4 18.4 15.2 20.2 12.7 116.2 136.1 21.8 38.0 18.4 9.7 204.3 167.7 14.1 15.1 23.2 5.3 23.3 205.5 11.8 49.0 14.1 9.6 25.0 9.4 21.5 27.0 17.3 161.1 9.5 35.2 3.5 150.8 13.6 43.6 20.2 15.5 21.8 15.6 284.9 29.0 23.8 6.4 7.9 285.9 224.1 20.3 23.9 61.7 15.1 20.2 25.6 74.8 38.4 12.0 90.2 17.1 56.1 19.3 34.4 25.7 34.0 15.7 47.8 15.8 32.0 19.3 9.6 23.7 125.3 27.6 29.0 26.1 38.8 48.6 19.7 1.4 77.1 17.3 40.8 38.8 10.9 35.9 51.1 22.9 8.0 24.7 29.3 20.9 66.6 30.6 12.0 33.4 36.5 33.3 37.8 36.2 28.7 41.9 15.1 13.5 16.5 17.7 59.1 41.7 28.4 29.2 20.6 20.2 1.7 3.3 0.7 0.7 1.2 0.4 1.1 0.7 0.4 2.2 2.0 0.8 0.3 0.5 5.3 0.7 0.8 0.8 0.9 112.9 204.4 166.7 138.7 116.2 136.1 204.3 167.7 205.5 161.1 150.8 284.9 48.6 35.3 26.5 83.2 22.2 70.6 36.0 28.3 75.1 10.3 76.9 27.2 10.1 67.2 19.9 106.7 235.6 53.3 7.6 296.5 3.9 17.5 2.9 59.2 40.3 45.2 157.2 20.4 174.2 36.5 12.1 64.0 84.1 175.2 100.1 16.7 48.9 170.0 21.3 6.7 108.1 160.0 14.2 46.5 46.5 6.1 110.0 48.6 74.7 81.5 91.0 9.0 13.4 257.3 2444.2 36.9 161.2 79.7 162.9 23.8 95.4 27.1 31.4 53.3 39.5 43.8 34.9 2.3 4.4 86.9 74.3 70.6 20.3 12.1 199.1 34.8 SLC66A3 "C2orf22, MGC33602, PQLC3" ENSG00000162976 "Solute carrier family 66 member 3" Q8N755 2 11155198-11178870 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 15.5;Cytotrophoblasts: 17.5;Extravillous trophoblasts: 82.4;Fibroblasts: 16.1;Hofbauer cells: 56.3" "Cancer enhanced" "Detected in all" "testis cancer: 72.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 64.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061607 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA061607: AB_2797264" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (2.19e-1)" "unprognostic (5.55e-2)" "unprognostic (1.65e-2)" "unprognostic (2.16e-1)" "unprognostic (1.09e-3)" "unprognostic (9.11e-2)" "unprognostic (3.14e-1)" "unprognostic (2.24e-1)" "unprognostic (4.93e-3)" "unprognostic (2.93e-1)" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.34e-1)" "unprognostic (4.00e-2)" 30.6 26.3 9.7 17.3 9.8 9.9 29.2 10.2 14.0 38.4 17.0 17.6 10.8 23.8 47.3 14.3 19.8 27.8 15.1 9.6 10.2 25.8 17.5 27.0 22.5 12.0 10.1 29.9 29.0 13.2 5.8 14.4 12.0 22.6 19.3 2.5 17.1 19.8 8.5 14.7 15.5 21.4 11.3 39.8 20.0 11.6 10.2 14.3 17.3 17.1 16.8 22.5 17.2 14.2 7.1 23.3 4.3 13.4 64.6 43.9 15.5 14.8 19.3 6.8 8.0 4.3 27.3 2.5 10.5 28.5 29.3 9.1 6.9 7.3 6.8 43.8 3.2 6.5 2.7 3.0 26.1 3.3 19.5 31.7 24.5 4.3 9.7 14.5 15.5 15.3 6.2 14.8 18.8 31.6 4.8 6.6 9.1 25.2 7.6 6.2 7.2 7.7 25.8 11.6 1.6 7.2 12.4 37.9 27.9 19.1 33.9 12.2 22.0 9.6 3.8 10.2 4.1 25.2 19.6 1.2 24.9 15.5 19.4 79.4 153.7 150.3 68.8 194.9 60.7 42.4 65.6 66.7 153.6 31.9 35.9 49.5 9.5 59.9 207.4 28.7 73.2 166.2 9.7 9.8 10.2 14.0 9.6 10.2 12.0 10.1 12.0 11.3 10.2 14.2 15.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 17.5 11.9 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 82.4 16.1 0.0 0.0 0.0 0.0 0.0 0.0 56.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 11.2 2.2 0.0 0.0 0.0 SLC9A5 NHE5 ENSG00000135740 "Solute carrier family 9 member A5" Q14940 16 67237683-67272191 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6;lymphoid tissue: 17.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 11.1;Horizontal cells: 16.8;Inhibitory neurons: 12.2;Oligodendrocyte precursor cells: 7.1;Spermatocytes: 17.2;Theca cells: 6.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041004, HPA041329" Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Plasma membrane" "HPA041004: AB_10794433, HPA041329: AB_10794373" "unprognostic (8.90e-2)" "unprognostic (9.70e-2)" "unprognostic (3.39e-3)" "unprognostic (1.37e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-2)" "unprognostic (5.17e-2)" "unprognostic (1.50e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-3)" "unprognostic (4.84e-2)" "unprognostic (9.85e-11)" "unprognostic (9.21e-2)" "unprognostic (1.95e-1)" "unprognostic (8.12e-3)" "unprognostic (9.07e-2)" 0.9 0.6 4.2 0.3 6.6 0.1 1.0 5.4 6.5 0.8 2.5 0.5 0.4 0.4 1.0 0.2 0.5 0.6 1.6 4.6 3.9 0.8 0.2 1.4 0.8 4.8 4.1 1.2 0.6 0.1 0.8 0.6 5.3 0.9 0.3 1.2 0.8 0.3 1.8 1.5 0.5 0.1 3.4 17.4 0.5 3.2 4.2 0.1 0.8 0.7 0.4 0.4 0.5 4.0 0.3 2.9 2.6 0.9 4.7 3.2 0.3 1.1 4.1 2.4 2.2 0.1 2.0 0.0 0.6 1.2 1.2 0.1 0.6 0.4 1.0 0.8 0.8 2.1 0.5 0.7 0.5 1.0 4.7 3.8 1.0 1.5 0.2 4.5 1.0 0.9 0.5 1.3 1.6 1.7 0.0 0.2 1.5 0.2 0.2 0.0 0.5 0.7 0.4 0.5 1.6 0.9 2.4 0.1 1.2 0.6 1.1 0.2 0.8 6.4 0.9 1.1 0.4 2.4 0.5 1.3 4.5 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.2 6.6 5.4 6.5 4.6 3.9 4.8 4.1 5.3 3.4 4.2 4.0 0.6 3.2 2.8 4.2 0.4 0.6 0.2 0.1 1.2 3.4 1.8 1.3 1.5 1.5 0.2 0.0 0.0 0.3 0.1 0.5 0.0 0.3 1.8 0.2 0.8 0.8 1.2 0.0 11.1 0.2 0.1 0.7 0.0 0.9 0.0 0.9 1.4 0.0 0.1 16.8 12.2 0.3 0.0 0.0 0.4 0.7 0.3 0.5 0.0 1.9 0.6 0.3 0.0 7.1 2.6 0.5 0.1 2.2 0.0 0.5 0.2 0.0 0.7 0.9 0.0 0.6 1.4 17.2 4.6 0.3 0.9 0.0 0.3 6.8 0.3 0.2 SLC9B2 "FLJ23984, NHA2, NHEDC2" ENSG00000164038 "Solute carrier family 9 member B2" Q86UD5 4 103019868-103085829 "Predicted membrane proteins, Transporters" "Antiport, Hydrogen ion transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 57.9;Exocrine glandular cells: 68.5;Inhibitory neurons: 57.2;Pancreatic endocrine cells: 94.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.8" "Group enriched" "Detected in many" 5 "B-cells: 5.1;NK-cells: 11.8;T-cells: 6.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047008 Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cell Junctions" "HPA047008: AB_2679901" "unprognostic (1.85e-1)" "unprognostic (5.43e-2)" "unprognostic (2.68e-1)" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.43e-2)" "unprognostic (3.78e-2)" "unprognostic (3.26e-1)" "unprognostic (2.53e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-5)" "unprognostic (2.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-2)" "unprognostic (2.35e-5)" 7.8 6.0 11.2 5.2 11.7 4.6 5.7 10.9 12.8 6.2 3.2 6.2 1.1 6.8 2.3 3.4 5.6 7.6 6.2 12.5 11.1 2.5 38.7 3.6 5.9 11.4 9.1 6.7 2.4 0.3 8.5 3.9 12.7 4.1 2.7 12.8 2.4 5.0 3.0 3.0 3.7 7.7 7.0 3.6 4.9 3.6 10.0 3.6 2.9 3.5 5.6 6.5 4.9 11.2 4.9 2.1 5.2 10.5 26.0 20.7 0.0 22.0 7.8 3.2 3.0 2.5 3.0 29.3 3.7 24.3 5.1 1.4 12.2 9.3 4.8 24.7 7.5 30.2 7.5 21.8 13.5 22.5 8.8 18.7 10.8 7.7 27.3 11.1 15.3 8.3 10.1 22.1 10.7 1.7 15.3 10.8 4.4 0.1 6.4 0.0 6.0 12.2 9.0 2.4 17.5 14.9 10.0 2.3 6.0 1.4 2.6 13.4 17.6 7.5 4.3 11.6 6.9 16.8 14.2 21.7 8.7 17.5 3.0 0.0 0.1 0.0 4.9 0.0 6.4 5.1 5.1 4.1 0.9 3.0 3.1 3.8 0.0 11.8 0.1 1.6 2.4 1.8 11.2 11.7 10.9 12.8 12.5 11.1 11.4 9.1 12.7 7.0 10.0 11.2 13.9 0.0 0.5 15.0 15.6 4.8 3.4 2.0 6.2 9.7 3.1 2.8 2.5 8.6 1.1 0.0 27.1 0.5 6.5 0.2 0.0 14.1 12.1 1.1 8.6 17.8 3.0 17.2 57.9 68.5 2.3 13.2 22.4 0.9 1.3 10.3 6.1 39.5 1.4 8.4 57.2 1.1 4.1 1.3 5.3 6.9 5.6 3.4 10.6 5.6 3.9 0.7 0.0 32.6 17.6 94.7 0.3 5.3 12.0 4.9 0.0 1.4 1.1 2.3 6.6 16.5 11.5 5.8 4.2 5.6 3.8 0.3 7.9 4.8 0.3 1.3 SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.3;Fibroblasts: 112.7;Sertoli cells: 85.5;Smooth muscle cells: 99.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 310.3;fHDF/TERT166: 116.0;RT4: 101.1;SH-SY5Y: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" 61.9 20.7 10.0 11.9 10.6 0.1 32.7 11.9 7.5 36.4 0.3 20.0 5.4 23.9 8.8 21.4 22.2 43.5 39.7 12.3 4.3 16.7 1.5 38.1 6.2 12.9 0.7 17.0 7.8 44.9 4.4 21.7 11.6 10.3 9.7 3.1 16.8 15.4 4.4 25.8 10.4 27.1 0.3 14.3 10.1 2.7 6.9 20.0 23.3 6.5 4.2 55.5 24.3 2.2 0.0 11.0 0.1 0.0 310.3 5.7 0.0 18.1 3.1 4.0 8.4 0.1 0.0 0.0 4.2 116.0 13.1 0.0 2.9 1.2 0.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 4.2 0.5 3.9 44.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 101.1 1.1 73.3 0.0 0.0 0.0 12.5 0.0 0.0 0.0 3.0 1.9 25.5 0.1 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 10.0 10.6 11.9 7.5 12.3 4.3 12.9 0.7 11.6 0.3 6.9 2.2 11.7 0.0 2.3 4.2 0.5 26.6 1.8 5.5 3.4 8.6 1.1 3.8 25.9 0.0 0.4 0.0 0.0 2.3 0.5 0.0 0.0 0.2 11.9 1.3 35.7 5.4 0.0 0.0 202.3 0.0 0.5 112.7 4.6 3.6 1.3 0.5 1.8 0.0 1.2 0.0 20.2 0.0 0.0 0.0 32.5 8.2 0.9 1.1 35.6 14.0 0.0 13.7 0.0 8.0 2.9 0.0 0.0 0.4 0.8 1.1 0.1 1.9 0.2 0.9 85.5 1.8 99.3 1.2 2.2 1.1 17.6 1.1 1.8 0.3 0.0 0.8 SMIM10L2B "LINC00087, NCRNA00087, RP11-85L21.2" ENSG00000196972 "Small integral membrane protein 10 like 2B" P0DMW5 X 135094985-135098712 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 29.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.1;Cardiomyocytes: 4.8;Horizontal cells: 11.8;Muller glia cells: 5.0;Peritubular cells: 3.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.8;GAMG: 2.1;HHSteC: 1.8;HSkMC: 2.9;NTERA-2: 1.6" NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (2.60e-2)" "unprognostic (3.08e-1)" "unprognostic (3.16e-2)" "unprognostic (1.18e-3)" "unprognostic (7.25e-3)" "unprognostic (9.55e-2)" "unprognostic (5.90e-2)" "unprognostic (6.02e-2)" "unprognostic (4.54e-2)" "unprognostic (7.05e-2)" "unprognostic (4.69e-2)" "unprognostic (1.13e-2)" "prognostic favorable (2.41e-5)" "unprognostic (2.03e-3)" "unprognostic (1.94e-1)" "unprognostic (2.32e-2)" "unprognostic (4.98e-2)" 1.2 3.3 17.7 0.4 19.3 0.0 1.3 6.2 24.2 3.1 0.5 1.4 0.4 2.7 2.1 2.0 3.1 0.8 11.1 19.2 23.4 3.7 1.3 1.4 0.4 20.3 20.9 4.5 1.0 5.8 3.7 0.4 29.5 3.5 0.4 2.2 3.0 2.1 0.8 1.6 0.8 1.4 7.7 1.0 1.6 5.6 16.9 0.1 2.2 0.8 0.3 1.2 2.2 14.4 0.0 0.0 1.3 1.2 1.8 0.2 0.6 0.4 0.2 0.2 0.3 0.5 0.0 0.0 0.2 0.2 2.1 0.1 0.4 0.4 0.0 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.1 2.9 0.2 0.0 0.1 0.3 0.1 0.6 0.0 0.0 0.1 0.0 0.4 0.0 1.6 0.3 0.1 0.0 0.3 0.0 0.7 0.2 0.6 0.2 0.2 0.1 0.0 1.3 0.0 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 19.3 6.2 24.2 19.2 23.4 20.3 20.9 29.5 7.7 16.9 14.4 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.1 1.0 1.8 4.8 0.0 0.0 0.0 0.0 0.1 0.2 0.0 1.9 0.3 0.1 0.1 1.2 0.7 1.2 0.0 0.0 0.7 0.1 1.1 0.0 0.2 0.0 1.3 0.7 1.7 0.0 11.8 0.0 0.3 0.0 0.3 0.0 0.8 3.1 0.1 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.5 0.0 3.8 0.0 0.4 0.1 1.7 0.0 1.5 0.0 0.6 2.3 1.0 0.5 0.8 0.0 0.3 0.0 0.9 0.1 0.4 SMIM3 "C5orf62, MSTP150, NID67" ENSG00000256235 "Small integral membrane protein 3" Q9BZL3 5 150778757-150796734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 161.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 85.5;Basal squamous epithelial cells: 80.8;granulocytes: 90.0;Macrophages: 79.3;Sertoli cells: 138.1;Smooth muscle cells: 77.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 409.9;ASC TERT1: 200.1;LHCN-M2: 193.8;U-87 MG: 291.5" "Low region specificity" "Detected in all" HPA075345 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA075345: AB_2686744" "unprognostic (2.33e-1)" "unprognostic (4.05e-2)" "unprognostic (1.35e-2)" "unprognostic (2.70e-2)" "unprognostic (9.45e-2)" "unprognostic (5.65e-2)" "unprognostic (4.57e-3)" "unprognostic (1.47e-1)" "unprognostic (3.90e-1)" "unprognostic (2.05e-2)" "unprognostic (9.71e-3)" "unprognostic (3.46e-3)" "prognostic unfavorable (1.15e-8)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.46e-3)" 161.0 36.2 20.5 25.5 20.3 89.5 71.5 20.9 26.4 21.9 42.1 26.8 13.4 16.2 22.6 16.8 30.2 25.7 36.8 20.5 22.1 34.9 12.2 30.9 11.7 23.3 21.5 25.9 33.7 26.9 15.1 46.0 23.6 27.6 19.1 20.4 14.0 24.1 15.0 12.5 23.0 28.3 20.7 25.2 21.6 4.1 23.5 17.7 21.0 15.5 8.8 29.0 18.7 19.6 13.8 4.5 7.3 60.8 409.9 200.1 15.9 52.3 114.6 19.2 77.2 21.5 35.3 0.0 3.1 55.1 12.7 10.7 12.5 11.8 28.6 0.2 3.8 20.0 2.8 9.9 72.4 19.7 130.0 167.9 23.6 54.2 25.1 122.3 6.4 46.6 5.5 0.4 193.8 10.5 28.5 27.0 3.8 10.7 12.5 15.2 1.2 0.0 20.6 10.2 1.8 4.7 7.8 1.1 16.1 8.1 25.4 120.6 10.1 84.2 15.2 65.9 27.5 0.0 0.4 0.2 291.5 75.0 10.8 68.7 41.0 72.4 20.8 17.2 12.7 1.3 14.5 14.4 19.4 0.2 14.1 12.1 42.7 13.0 16.2 57.3 2.3 38.0 20.5 20.3 20.9 26.4 20.5 22.1 23.3 21.5 23.6 20.7 23.5 19.6 53.7 6.4 8.6 2.6 3.2 0.0 85.5 0.0 80.8 0.8 12.0 16.6 9.9 7.2 2.5 7.3 0.0 8.5 22.8 4.0 13.7 6.4 0.8 1.3 11.1 25.4 4.8 8.4 1.0 31.3 5.0 53.5 2.6 1.1 90.0 1.7 13.2 1.0 45.2 0.0 2.0 36.8 0.0 34.2 0.0 0.6 14.0 79.3 0.0 16.9 30.2 62.1 11.3 5.5 0.1 18.2 1.1 36.9 3.5 15.9 3.9 8.8 0.0 1.9 138.1 72.3 77.2 0.1 0.5 20.1 0.0 8.1 28.8 3.0 7.4 40.1 SMPD1 ASM ENSG00000166311 "Sphingomyelin phosphodiesterase 1" P17405 11 6390440-6394998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Neurodegeneration, Niemann-Pick disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 131.3;Late spermatids: 200.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 139.1;fHDF/TERT166: 144.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2700000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (8.76e-2)" "unprognostic (2.66e-1)" "unprognostic (6.99e-2)" "unprognostic (2.28e-3)" "prognostic unfavorable (7.72e-5)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (4.90e-2)" "unprognostic (8.06e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.47e-4)" "unprognostic (4.35e-2)" "prognostic favorable (4.57e-6)" "unprognostic (4.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" "unprognostic (1.71e-1)" 21.8 36.5 38.8 13.9 44.7 7.3 20.1 45.1 43.0 21.2 33.9 25.3 16.8 20.9 14.4 20.6 14.6 21.5 55.8 39.1 43.0 73.7 95.3 31.3 14.6 42.7 42.6 17.9 32.8 34.2 41.9 21.6 43.3 29.4 14.9 8.5 29.0 20.0 37.9 37.9 23.8 17.6 40.9 21.1 25.4 14.0 47.5 17.8 34.0 29.4 11.0 23.6 21.0 46.8 16.4 13.1 10.1 26.5 139.1 72.2 17.1 60.4 95.0 27.7 33.0 22.0 11.9 4.7 27.4 144.0 59.3 7.4 8.4 12.7 13.0 21.0 9.6 5.1 19.5 6.0 62.3 3.7 37.4 96.0 23.4 25.9 17.7 100.9 61.6 1.7 9.1 30.5 58.9 17.0 0.1 6.5 3.9 23.2 22.3 1.2 5.5 7.0 23.9 6.2 17.0 9.7 27.6 19.5 38.5 12.9 7.3 7.0 53.9 103.0 10.9 59.1 15.4 37.6 44.0 3.5 93.7 10.8 47.1 1.9 2.5 3.4 6.4 2.1 5.0 1.5 5.5 5.0 1.3 3.1 10.0 10.1 2.5 6.6 0.6 1.7 4.7 3.2 38.8 44.7 45.1 43.0 39.1 43.0 42.7 42.6 43.3 40.9 47.5 46.8 14.1 25.6 14.4 10.7 12.2 7.9 22.8 15.3 6.8 12.6 13.7 9.0 37.7 24.3 12.8 25.8 25.0 38.8 11.5 131.3 11.7 53.4 50.0 6.2 13.0 18.6 23.8 9.9 5.8 38.2 14.4 31.4 15.8 21.0 10.8 9.4 26.7 88.5 34.1 20.2 5.5 20.3 24.4 15.5 6.2 200.7 11.5 15.8 55.2 4.7 7.8 16.4 36.0 6.6 15.5 24.7 83.1 13.5 23.1 26.0 51.7 75.1 2.4 5.2 0.0 8.9 17.1 1.4 3.1 7.5 8.0 34.3 23.3 10.2 18.0 15.4 SMYD1 "BOP, KMT3D, ZMYND22" ENSG00000115593 "SET and MYND domain containing 1" Q8NB12 2 88067825-88113384 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "heart muscle: 160.4;skeletal muscle: 493.6;tongue: 301.3" "Cell type enriched" "Detected in some" 27 "Cardiomyocytes: 208.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.9;stomach cancer: 1.6" "Region enriched" "Detected in some" 4 "basal ganglia: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HSkMC: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA062282 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA062282: AB_2684736" "unprognostic (1.93e-2)" "unprognostic (2.49e-1)" "unprognostic (4.09e-2)" "unprognostic (8.51e-3)" "unprognostic (2.74e-1)" "unprognostic (3.91e-1)" "unprognostic (8.81e-3)" "unprognostic (1.40e-1)" 0.0 0.0 0.2 0.2 4.1 0.0 5.4 0.1 1.0 0.0 0.0 17.9 2.0 0.0 0.0 7.3 0.0 0.0 160.4 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 2.4 0.0 0.0 0.3 4.0 1.9 0.0 3.9 0.0 493.6 0.1 7.0 28.1 0.1 0.0 7.3 0.3 0.1 0.4 0.1 301.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.1 0.1 1.0 0.4 0.1 0.1 0.2 0.3 0.1 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.7 208.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SNAI2 "SLUG, SLUGH, SLUGH1, SNAIL2" ENSG00000019549 "Snail family transcriptional repressor 2" O43623 8 48917598-48921740 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Deafness, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 162.8;Basal prostatic cells: 119.4;Basal respiratory cells: 98.9;Endometrial stromal cells: 129.2;Melanocytes: 87.2;Suprabasal keratinocytes: 147.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 243.2;ASC TERT1: 247.8;HSkMC: 181.3;hTERT-HME1: 180.3;LHCN-M2: 228.8;U-138 MG: 206.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB011671 Supported Approved Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB011671: AB_777968" "unprognostic (3.52e-2)" "unprognostic (3.95e-1)" "unprognostic (1.55e-1)" "unprognostic (1.89e-2)" "unprognostic (3.78e-2)" "unprognostic (1.74e-2)" "unprognostic (1.79e-1)" "unprognostic (1.04e-2)" "unprognostic (4.24e-2)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.83e-4)" "unprognostic (2.38e-1)" "prognostic unfavorable (4.69e-8)" "unprognostic (1.65e-3)" "unprognostic (3.76e-2)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.16e-4)" 28.2 10.6 0.5 15.7 0.8 0.4 22.9 3.6 1.4 51.1 1.7 11.6 4.3 43.0 11.3 15.8 34.4 21.8 15.0 0.8 0.5 12.4 9.6 11.1 8.1 0.8 0.5 40.8 8.0 3.6 2.3 16.2 0.6 19.8 7.6 0.1 16.8 23.2 4.6 39.8 11.5 27.5 0.4 14.2 9.4 3.7 0.6 6.9 9.5 7.7 7.9 37.8 51.3 0.5 17.7 0.6 38.5 0.4 243.2 247.8 0.1 38.6 69.0 38.1 52.3 0.0 17.4 0.0 0.0 50.1 56.7 28.9 0.4 111.8 40.2 0.0 0.8 0.0 7.2 0.1 88.5 0.1 0.1 181.3 116.8 31.9 180.3 5.4 1.3 0.0 0.0 18.5 228.8 0.3 0.0 0.1 2.3 0.0 34.7 0.0 122.2 0.2 0.1 6.8 5.1 3.8 3.3 0.1 69.2 18.9 0.2 0.2 10.6 206.6 7.4 36.6 20.9 0.0 0.1 4.2 74.9 0.0 78.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 3.6 1.4 0.8 0.5 0.8 0.5 0.6 0.4 0.6 0.5 11.7 0.0 0.0 0.0 0.1 162.8 119.4 98.9 60.9 1.9 2.1 22.0 1.2 1.5 14.0 0.0 0.0 1.7 0.3 0.0 0.0 3.0 0.6 5.2 129.2 19.5 0.0 0.0 0.6 2.3 0.5 69.9 0.0 4.8 0.0 0.0 40.0 6.8 1.7 0.0 0.5 0.0 10.2 0.8 30.7 1.7 73.7 1.9 87.2 0.0 0.0 0.0 0.0 1.0 0.0 6.1 0.0 67.4 1.4 18.4 0.0 0.0 2.4 0.2 52.6 24.7 59.2 0.2 0.4 32.3 147.9 2.2 2.3 21.8 0.0 25.0 SNED1 "FLJ00133, Snep, SST3" ENSG00000162804 "Sushi, nidogen and EGF like domains 1" Q8TER0 2 240998618-241095568 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 95.0;Excitatory neurons: 86.0;Leydig cells: 95.1;Microglial cells: 77.8;Peritubular cells: 71.1;Skeletal myocytes: 53.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "ASC TERT1: 410.4;HSkMC: 211.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036414, HPA036415" Uncertain "Secreted to blood" NA NA 27000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA036414: AB_10960852, HPA036415: AB_10964128" "unprognostic (1.41e-1)" "unprognostic (3.92e-2)" "unprognostic (1.52e-2)" "unprognostic (9.37e-3)" "unprognostic (1.57e-3)" "unprognostic (4.62e-2)" "unprognostic (7.77e-4)" "unprognostic (3.49e-2)" "unprognostic (4.96e-1)" "unprognostic (7.85e-3)" "unprognostic (3.42e-2)" "unprognostic (2.06e-2)" "unprognostic (2.80e-2)" "unprognostic (1.16e-1)" "unprognostic (3.72e-1)" "unprognostic (5.51e-3)" "unprognostic (4.95e-3)" 23.8 9.3 4.2 6.4 8.5 1.2 15.8 14.1 6.9 34.1 32.4 7.3 4.5 18.0 11.8 6.1 21.6 18.7 11.1 10.7 11.7 7.1 8.0 13.3 4.7 8.3 6.4 21.9 7.3 3.1 7.2 1.9 4.8 12.5 3.4 2.5 14.6 7.5 19.8 12.1 10.4 6.3 0.6 14.1 5.7 9.3 2.2 3.3 30.2 9.1 2.9 11.5 10.7 5.9 0.1 0.6 0.4 4.8 61.1 410.4 0.3 2.4 1.5 0.5 0.2 0.2 0.2 0.1 1.0 4.4 0.5 0.2 0.4 0.0 0.3 2.7 1.0 0.2 4.5 0.4 2.6 0.2 0.5 211.6 0.1 0.5 0.3 28.4 9.5 0.2 0.1 2.7 11.5 2.4 1.6 0.2 0.7 0.1 0.3 0.2 8.1 0.1 5.6 0.5 0.8 0.3 1.9 8.3 4.2 0.6 1.8 0.8 23.7 8.7 0.6 50.9 1.5 0.8 0.4 1.5 11.7 0.1 2.6 0.0 0.0 0.0 0.0 0.3 0.3 1.9 0.4 0.2 0.0 0.6 0.2 0.2 0.0 0.0 0.7 0.0 0.4 0.0 4.2 8.5 14.1 6.9 10.7 11.7 8.3 6.4 4.8 0.6 2.2 5.9 8.0 6.4 11.0 95.0 8.4 3.6 0.9 0.4 2.8 2.8 1.1 1.8 2.4 1.5 8.5 5.5 0.0 0.1 0.3 0.3 0.0 1.2 1.3 10.6 16.8 10.9 2.4 3.2 86.0 1.2 0.1 22.1 2.6 10.7 0.0 5.0 22.9 5.8 0.2 1.7 32.5 0.2 0.0 2.9 5.9 5.9 95.1 2.7 1.8 77.8 0.6 7.4 0.0 11.6 7.0 0.7 0.1 71.1 0.9 3.0 0.0 0.5 4.2 1.2 26.3 53.7 4.9 0.6 1.5 0.7 2.6 0.4 1.8 36.4 0.5 0.6 SNX29 "FLJ12363, RUNDC2A" ENSG00000048471 "Sorting nexin 29" Q8TEQ0 16 11976734-12574287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 354.5;Late spermatids: 430.7;Microglial cells: 169.6;Oligodendrocytes: 241.6;Rod photoreceptor cells: 256.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 22.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008889, HPA062810" Approved Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Nucleoli, Cytosol" "HPA008889: AB_1079856, HPA062810: " "unprognostic (2.50e-1)" "unprognostic (4.12e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (9.82e-3)" "unprognostic (2.29e-2)" "unprognostic (1.12e-1)" "unprognostic (5.38e-2)" "unprognostic (2.18e-2)" "unprognostic (7.44e-2)" "unprognostic (6.08e-2)" "prognostic favorable (1.38e-7)" "unprognostic (3.85e-3)" "unprognostic (4.54e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (1.03e-4)" 8.6 3.5 7.4 8.2 18.8 9.5 6.2 13.6 11.8 6.6 7.4 5.3 2.3 5.8 2.6 8.2 8.4 4.8 4.5 7.5 9.9 19.0 2.3 6.8 13.0 17.0 15.6 10.2 3.5 22.5 7.1 8.0 18.3 3.5 3.4 23.8 5.6 4.8 6.0 6.9 4.6 5.7 11.4 9.0 4.3 8.5 17.9 21.0 6.5 5.7 16.0 6.3 5.0 26.7 5.0 2.9 4.4 3.5 25.4 20.8 5.7 10.7 29.1 4.3 4.7 0.6 5.7 18.7 13.9 16.6 2.8 4.2 2.9 6.8 6.2 7.2 3.0 2.5 2.5 6.4 4.9 2.7 6.6 19.1 4.4 6.3 2.8 6.5 7.6 6.1 3.9 5.2 4.4 6.7 5.0 3.1 2.4 3.2 2.6 11.3 5.6 15.2 19.3 4.6 5.2 4.4 12.2 7.2 2.5 3.8 4.1 3.2 11.7 7.6 3.0 5.8 2.1 29.5 24.4 11.5 14.1 2.8 4.9 3.8 6.9 1.6 2.0 4.5 2.5 10.6 4.3 2.7 2.5 22.3 5.2 3.6 2.5 1.3 2.3 7.4 4.0 1.9 7.4 18.8 13.6 11.8 7.5 9.9 17.0 15.6 18.3 11.4 17.9 26.7 14.4 12.8 22.9 71.2 61.0 15.3 6.5 5.3 19.9 63.9 8.5 7.4 9.7 4.3 10.8 16.5 354.5 18.6 26.9 4.4 21.5 4.6 124.0 35.3 27.8 13.8 13.1 6.1 59.0 2.9 5.0 20.8 14.8 62.6 42.5 15.2 17.9 4.8 28.7 92.5 54.6 4.6 8.2 29.3 39.6 430.7 21.5 36.7 12.4 169.6 24.3 23.1 16.5 51.8 241.6 7.7 4.3 15.4 23.9 3.6 3.3 42.6 27.2 256.1 6.6 20.8 14.2 20.0 10.8 21.9 15.5 17.1 15.4 14.1 4.0 5.5 SOD2 GClnc1 ENSG00000112096 "Superoxide dismutase 2" P04179 6 159669069-159762529 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 1083.7;skeletal muscle: 3230.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2508.2;Prostatic glandular cells: 3524.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "neutrophil: 4470.5" "Lineage enriched" "Detected in all" 10 "granulocytes: 4470.5" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1611.9;GAMG: 614.3;HSkMC: 688.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001814, CAB002013" Supported Enhanced Mitochondria NA NA 55000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB002013: , HPA001814: AB_1080134" "unprognostic (2.47e-2)" "unprognostic (2.77e-3)" "unprognostic (1.14e-1)" "unprognostic (1.57e-2)" "unprognostic (1.31e-1)" "unprognostic (1.69e-1)" "unprognostic (1.49e-1)" "unprognostic (3.10e-2)" "unprognostic (1.37e-1)" "unprognostic (6.67e-2)" "unprognostic (2.76e-2)" "unprognostic (7.14e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (8.12e-2)" "unprognostic (4.14e-2)" "unprognostic (5.99e-2)" "unprognostic (1.82e-1)" 324.8 245.9 66.8 522.8 43.2 1083.7 169.0 37.8 125.8 92.6 99.7 126.4 60.5 105.4 7.2 136.5 118.5 121.8 178.5 37.0 101.0 252.4 459.8 266.5 64.8 250.0 96.1 55.8 212.3 69.1 42.7 62.9 192.9 130.8 37.9 25.1 328.8 43.9 3230.1 90.0 83.7 108.4 62.5 81.4 120.4 39.6 153.1 38.2 67.2 312.6 65.0 514.9 97.9 85.4 35.8 46.3 37.3 85.1 229.0 378.7 20.5 52.7 1611.9 57.7 131.1 91.3 19.4 70.7 144.5 54.1 614.3 58.9 39.1 42.5 42.4 71.2 87.2 74.5 71.8 152.3 169.5 74.0 31.9 688.9 68.5 180.9 133.6 40.7 30.0 44.9 106.7 82.2 55.4 37.6 60.3 46.6 63.3 41.5 55.4 79.6 50.3 63.9 106.2 56.6 71.5 29.5 105.1 52.4 21.4 14.1 33.1 33.7 30.4 168.6 62.1 92.5 87.9 37.8 100.2 86.5 186.7 57.4 23.6 146.3 364.4 181.1 38.8 273.9 43.4 43.4 54.9 38.5 105.2 38.3 45.0 36.9 4470.5 19.1 445.3 14.8 87.9 340.0 66.8 43.2 37.8 125.8 37.0 101.0 250.0 96.1 192.9 62.5 153.1 85.4 303.2 201.9 746.1 13.4 99.0 684.7 1144.9 2508.2 114.4 45.6 150.2 96.6 0.0 287.4 613.3 237.3 45.9 18.3 43.8 153.9 86.1 1400.2 318.2 281.7 649.8 593.0 79.6 101.2 31.1 1389.7 51.2 1098.4 103.5 1080.1 112.3 23.1 58.9 395.0 292.0 32.0 30.1 92.7 339.7 333.3 1425.8 111.5 58.1 1031.2 521.2 15.9 339.9 50.4 35.0 8.5 12.2 581.6 111.3 65.1 101.2 3524.0 128.6 530.1 269.6 61.8 39.5 1164.0 407.3 91.7 51.4 258.7 681.8 27.2 119.4 38.3 148.1 1195.7 SP3 SPR-2 ENSG00000172845 "Sp3 transcription factor" Q02447 2 173880850-173965702 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004580, HPA032145, HPA032146" Supported Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "CAB004580: AB_628274, HPA032145: , HPA032146: AB_2732465" "unprognostic (1.94e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-1)" "unprognostic (2.39e-3)" "unprognostic (2.50e-1)" "unprognostic (4.92e-2)" "unprognostic (5.54e-3)" "unprognostic (6.36e-2)" "unprognostic (2.76e-3)" "unprognostic (3.27e-1)" "unprognostic (5.01e-3)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.46e-5)" "unprognostic (2.78e-1)" "unprognostic (2.07e-1)" "unprognostic (8.02e-2)" "unprognostic (1.69e-1)" 32.6 19.8 15.8 35.2 16.0 53.1 43.1 21.3 19.8 50.9 16.1 34.3 26.9 45.1 34.6 32.1 37.1 28.9 23.8 14.2 17.1 29.7 40.1 29.9 46.1 16.9 16.7 40.3 24.9 43.1 13.2 49.1 16.4 31.9 38.9 21.0 26.1 30.4 22.5 38.5 29.6 36.3 16.3 38.6 27.0 25.2 15.5 68.0 47.5 33.7 53.8 33.7 28.0 18.5 41.6 34.5 74.6 45.8 91.8 82.3 83.5 47.5 67.1 62.2 66.1 56.8 59.7 65.1 39.3 65.0 46.3 41.0 57.8 46.0 91.7 55.2 21.2 65.9 33.9 54.0 45.5 60.4 48.9 60.6 53.2 72.9 63.6 48.4 49.4 51.3 51.4 86.8 65.7 44.4 84.0 49.9 66.1 60.1 37.8 74.2 68.5 53.0 48.4 55.8 67.8 48.1 67.1 38.1 52.4 81.7 30.0 80.0 44.1 70.6 61.8 47.5 50.4 58.8 46.7 85.8 53.0 41.6 67.2 8.9 9.4 13.0 11.6 7.0 12.9 9.5 12.3 12.3 9.9 7.4 13.8 12.8 27.3 21.9 10.3 6.2 13.8 9.9 15.8 16.0 21.3 19.8 14.2 17.1 16.9 16.7 16.4 16.3 15.5 18.5 36.1 19.2 22.9 44.7 55.2 57.6 31.7 25.7 64.9 29.1 36.8 23.4 18.8 14.3 23.3 20.2 27.1 30.9 67.9 37.9 11.7 18.6 4.3 22.3 57.8 33.9 30.5 31.7 52.7 19.3 42.7 43.9 17.9 29.5 23.5 31.3 32.2 43.8 24.6 23.5 50.7 28.8 20.3 54.1 72.8 7.1 45.4 55.6 42.7 81.5 39.0 30.5 46.4 60.3 74.7 30.8 22.9 36.9 63.7 34.2 22.1 24.4 26.6 20.2 19.7 40.4 53.4 10.5 20.4 48.6 57.0 34.6 50.8 26.0 29.0 59.0 SPAG8 "BS-84, CT142, HSD-1, hSMP-1, SPAG3" ENSG00000137098 "Sperm associated antigen 8" Q99932 9 35808045-35812272 "Predicted intracellular proteins" "Cell cycle, Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 5.6;choroid plexus: 16.4;fallopian tube: 14.2;testis: 10.3" "Cell type enhanced" "Detected in many" "Early spermatids: 51.2;Endometrial ciliated cells: 75.7;Late spermatids: 26.5;Respiratory ciliated cells: 123.3;Spermatocytes: 58.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "ASC diff: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068012 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "HPA068012: AB_2685941" "unprognostic (1.01e-4)" "unprognostic (3.52e-3)" "unprognostic (6.36e-3)" "prognostic favorable (2.15e-4)" "unprognostic (2.62e-1)" "unprognostic (5.04e-2)" "unprognostic (1.65e-2)" "unprognostic (1.47e-2)" "unprognostic (1.59e-1)" "unprognostic (4.65e-2)" "unprognostic (1.37e-4)" "unprognostic (1.05e-1)" "unprognostic (1.22e-2)" "unprognostic (5.41e-2)" "unprognostic (1.33e-1)" "unprognostic (1.09e-1)" "unprognostic (3.22e-3)" 0.3 0.5 0.9 0.2 0.8 0.3 0.3 0.9 1.1 1.7 16.4 0.8 0.4 0.7 1.0 0.2 14.2 0.6 1.7 1.4 0.8 0.7 0.1 1.3 0.4 3.8 5.6 1.3 0.3 1.0 2.5 0.2 2.9 0.7 0.1 0.2 0.3 0.4 0.4 0.2 0.3 0.2 2.0 0.6 0.4 10.3 1.0 0.7 1.4 0.8 0.3 0.5 0.3 1.3 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.3 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.5 0.0 0.3 0.1 0.4 0.3 0.0 0.0 0.0 0.1 0.3 0.2 0.4 0.2 0.6 0.3 0.0 0.0 0.3 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.2 0.3 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.5 0.3 0.2 1.4 0.7 0.0 0.6 0.4 0.2 0.0 0.4 0.6 1.1 0.4 0.3 0.8 0.0 0.9 0.0 0.0 1.0 0.4 0.9 0.8 0.9 1.1 1.4 0.8 3.8 5.6 2.9 2.0 1.0 1.3 1.0 0.0 1.5 8.1 1.0 0.4 1.0 6.3 0.0 4.9 0.8 1.8 3.6 0.0 10.4 5.5 8.4 0.3 1.0 0.0 1.9 0.4 51.2 75.7 1.1 1.0 3.0 0.4 4.4 0.0 0.1 1.4 0.5 1.4 1.3 0.7 1.1 0.1 1.0 3.3 4.7 0.0 8.2 0.3 0.9 26.5 1.5 1.9 0.0 1.0 1.9 5.7 0.0 3.0 7.0 0.1 0.0 1.2 0.9 0.6 0.1 1.6 123.3 8.5 0.0 1.5 4.5 58.8 3.1 0.0 0.6 0.1 1.1 1.4 0.1 0.3 SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 737.1;Endometrial stromal cells: 1209.0;Endothelial cells: 781.9;Fibroblasts: 1032.1;Peritubular cells: 1111.1;Sertoli cells: 2353.5;Smooth muscle cells: 1527.3;Theca cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cell line enhanced" "Detected in many" "ASC diff: 4911.5;BJ: 4101.8;fHDF/TERT166: 6492.5;WM-115: 4789.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" 1661.2 406.4 578.0 436.4 922.0 32.4 528.6 733.1 339.2 837.2 297.8 355.6 110.5 538.9 112.7 307.7 271.4 1526.8 563.5 362.9 1554.2 176.1 158.5 498.0 232.1 1370.4 1251.5 348.2 119.2 273.1 111.4 2184.6 1224.8 227.1 185.2 36.4 113.1 378.0 258.2 286.1 157.4 1251.5 995.9 260.8 143.3 406.7 1135.4 70.9 294.1 473.5 131.6 829.5 249.0 1088.4 5.9 5.0 1196.5 57.5 4911.5 1596.0 112.6 4101.8 1336.6 1649.3 1693.8 5.5 4.2 2.0 953.7 6492.5 272.0 56.7 153.4 316.2 555.0 4.8 57.1 56.7 0.4 116.8 1441.6 2.9 5.4 2567.2 436.9 1233.8 170.8 1903.1 2315.1 13.5 53.7 44.6 944.1 0.4 4.7 35.5 556.2 0.4 4.4 2.9 1192.9 4.3 0.5 0.5 45.5 88.4 2.8 1.4 534.9 1922.1 4.7 138.2 2759.9 771.0 1195.2 350.2 1304.4 3.7 6.0 7.6 648.4 3.7 4789.0 10.4 8.7 2.7 1.0 0.3 0.0 0.1 0.0 0.1 2.3 0.2 0.3 0.0 24.3 0.0 0.1 1.9 0.0 123.9 578.0 922.0 733.1 339.2 362.9 1554.2 1370.4 1251.5 1224.8 995.9 1135.4 1088.4 737.1 83.3 27.5 7.2 6.8 164.8 25.7 23.8 28.5 85.7 11.2 100.5 43.6 5.7 18.8 16.5 2.1 115.4 2.8 0.1 0.0 4.6 14.2 41.6 1209.0 781.9 0.0 15.1 4.3 0.4 354.3 1032.1 9.7 31.5 12.0 146.5 668.6 9.9 108.2 1.7 2.9 0.0 0.0 50.0 175.7 46.8 319.3 92.0 234.7 38.4 10.7 13.6 3.1 21.6 37.3 5.5 0.0 1111.1 4.1 7.7 0.0 42.0 7.8 72.7 2353.5 510.4 1527.3 14.2 10.9 4.8 108.3 147.4 21.1 987.4 0.0 5.3 SPON2 DIL1 ENSG00000159674 "Spondin 2" Q9BUD6 4 1166932-1208962 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 187.1" "Cell type enhanced" "Detected in many" "dendritic cells: 427.0;Endometrial stromal cells: 256.6;Extravillous trophoblasts: 355.8;Fibroblasts: 257.7;NK-cells: 1096.8" "Cancer enriched" "Detected in all" 7 "prostate cancer: 243.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 255.9" "Lineage enriched" "Detected in all" 5 "T-cells: 255.9" "Group enriched" "Detected in many" 5 "HHSteC: 303.8;HSkMC: 546.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040170, HPA066095" Approved Approved Vesicles "Secreted to blood" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040170: AB_2676868, HPA066095: AB_2685615" "unprognostic (1.22e-1)" "unprognostic (3.56e-1)" "unprognostic (3.07e-2)" "prognostic favorable (2.03e-4)" "unprognostic (7.64e-2)" "unprognostic (6.28e-2)" "unprognostic (2.70e-3)" "unprognostic (2.28e-3)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-2)" "unprognostic (2.74e-3)" "unprognostic (1.22e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (9.22e-4)" 66.2 40.4 4.0 18.8 7.7 19.5 50.6 15.6 3.9 161.4 3.5 51.5 18.5 187.1 4.4 40.6 49.7 32.2 35.5 3.5 0.8 37.1 79.1 63.0 3.9 2.9 1.7 34.4 18.7 0.9 15.1 19.2 3.5 111.8 7.2 0.7 28.8 8.4 19.1 38.3 63.5 42.7 0.2 26.9 43.8 4.7 1.8 1.8 16.3 6.6 1.0 68.4 94.0 1.5 0.4 0.6 0.0 0.0 10.2 79.0 3.0 6.2 5.0 0.8 1.0 0.0 0.1 1.8 9.7 26.9 0.9 45.0 0.0 0.2 0.0 0.3 0.1 0.2 3.0 12.7 303.8 0.2 1.5 546.6 0.0 0.6 0.0 0.0 0.0 4.1 0.3 9.2 0.0 0.3 5.3 12.2 3.5 9.7 0.7 1.0 3.3 7.9 0.0 0.0 1.7 1.1 1.1 0.0 2.9 1.7 0.4 1.5 0.1 0.2 0.9 20.5 0.0 1.3 2.7 0.6 0.1 6.5 0.0 3.7 0.9 1.0 255.9 1.1 5.5 0.7 33.1 105.8 0.4 1.0 14.4 96.8 9.8 50.4 2.2 42.9 0.1 123.2 4.0 7.7 15.6 3.9 3.5 0.8 2.9 1.7 3.5 0.2 1.8 1.5 9.8 0.0 5.6 1.3 6.6 36.8 2.0 82.5 2.2 3.7 5.1 3.8 4.0 24.3 43.0 1.8 0.0 3.4 427.0 9.7 1.9 3.8 0.2 12.7 256.6 5.7 13.8 4.0 8.4 1.3 355.8 257.7 10.7 6.6 6.3 0.2 15.4 40.4 12.8 0.0 0.6 9.7 73.2 5.8 15.4 0.5 29.8 9.5 26.6 6.5 9.2 0.9 1096.8 0.5 0.7 1.5 6.7 9.4 64.0 15.8 16.3 28.3 32.6 0.4 6.6 22.5 89.9 0.2 0.5 21.3 21.5 38.9 100.8 8.1 7.9 13.2 SRL SAR ENSG00000185739 Sarcalumenin Q86TD4 16 4189374-4242080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 41 "heart muscle: 280.1;skeletal muscle: 510.3;tongue: 382.3" "Cell type enriched" "Detected in some" 16 "Cardiomyocytes: 247.3" "Group enriched" "Detected in some" 5 "head and neck cancer: 1.5;thyroid cancer: 5.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "HSkMC: 4.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in some" "basal ganglia: 5.3" "HPA041535, HPA045520" Enhanced "Intracellular and membrane" NA NA 230000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA041535: AB_2677538, HPA045520: AB_2679358" "unprognostic (1.24e-2)" "unprognostic (1.36e-2)" "unprognostic (1.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.21e-1)" "unprognostic (8.11e-2)" "unprognostic (2.04e-7)" "unprognostic (1.41e-1)" "unprognostic (8.28e-2)" "unprognostic (7.40e-4)" "unprognostic (4.91e-2)" "unprognostic (8.70e-2)" "unprognostic (7.78e-4)" "unprognostic (3.33e-2)" "unprognostic (2.15e-1)" "unprognostic (1.51e-3)" "unprognostic (1.68e-4)" 3.0 0.4 1.0 1.2 1.0 0.2 1.7 1.0 1.5 3.2 0.8 1.3 0.4 3.0 2.3 9.6 3.1 1.8 280.1 0.8 1.2 1.4 0.4 1.2 0.7 1.2 1.3 1.3 0.6 0.2 0.5 1.3 1.1 5.6 1.1 8.5 6.4 2.6 510.3 1.1 1.7 3.4 1.0 2.2 1.1 1.0 1.1 1.7 2.3 382.3 1.1 1.4 1.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 1.0 1.0 1.0 1.5 0.8 1.2 1.2 1.3 1.1 1.0 1.1 1.0 0.5 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 1.0 0.0 0.0 247.3 0.0 0.0 1.8 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 0.0 0.0 0.4 0.0 0.0 8.5 0.0 0.1 0.0 0.2 2.9 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.3 0.0 1.8 0.1 0.0 1.0 0.0 1.2 0.0 1.0 0.3 0.1 0.0 3.8 0.0 0.3 0.0 0.2 0.0 12.1 6.6 5.5 15.4 0.1 0.2 0.0 0.4 0.0 0.1 0.4 0.0 0.1 SRPX ETX1 ENSG00000101955 "Sushi repeat containing protein X-linked" P78539 X 38149336-38220924 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 215.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 256.9;Granulosa cells: 138.9;Hepatic stellate cells: 418.7;Leydig cells: 110.3;Peritubular cells: 95.2" "Group enriched" "Detected in all" 5 "glioma: 64.2;melanoma: 70.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 49 "plasmacytoid DC: 7.8" "Lineage enriched" "Detected in single" 49 "dendritic cells: 7.8" "Cell line enhanced" "Detected in many" "ASC diff: 3742.4;ASC TERT1: 827.3;HSkMC: 1258.3;HUVEC TERT2: 803.2" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "spinal cord: 12.4" "Secreted - unknown location" NA NA 140000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.35e-1)" "unprognostic (1.09e-3)" "unprognostic (1.08e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (6.48e-2)" "unprognostic (3.83e-3)" "unprognostic (3.50e-2)" "unprognostic (2.31e-1)" "unprognostic (4.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.30e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (7.80e-13)" "unprognostic (6.94e-3)" "unprognostic (3.90e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.36e-4)" 215.2 37.2 8.2 22.4 12.8 0.1 148.0 17.8 5.9 48.6 5.2 83.0 7.9 56.1 39.6 36.6 113.4 58.1 93.3 7.0 16.7 7.4 17.7 46.6 5.0 13.2 14.2 21.4 23.9 2.7 4.6 88.9 15.4 18.3 24.8 1.6 22.9 15.3 15.6 29.2 52.6 52.9 15.1 1.7 42.5 6.7 13.8 19.2 59.1 13.6 5.3 103.8 42.9 15.4 0.3 5.0 12.1 0.2 3742.4 827.3 0.9 35.3 67.8 11.9 20.2 0.5 3.6 0.1 0.3 74.3 119.9 1.9 2.0 30.8 9.8 0.2 13.8 0.1 1.0 0.4 167.8 3.0 0.4 1258.3 2.6 114.9 58.3 132.8 803.2 1.4 0.1 0.2 130.1 1.7 0.5 0.1 10.2 1.8 26.2 0.0 43.5 6.4 0.8 2.3 2.3 2.3 1.7 0.1 170.1 31.2 0.0 0.4 349.1 82.2 42.3 108.8 103.7 0.0 0.1 0.1 239.0 3.1 106.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 0.0 0.1 8.2 12.8 17.8 5.9 7.0 16.7 13.2 14.2 15.4 15.1 13.8 15.4 28.7 3.2 1.3 17.0 0.6 15.3 2.2 2.8 7.4 0.4 2.9 8.6 14.2 0.0 0.2 1.8 0.0 3.6 2.1 2.5 0.0 0.3 0.7 1.1 35.1 67.2 0.0 2.7 1.9 0.4 5.4 256.9 1.5 0.8 0.0 138.9 418.7 2.5 6.1 0.0 2.7 5.8 0.0 11.4 15.2 4.9 110.3 1.6 74.7 1.0 0.0 0.2 0.0 2.5 0.3 0.8 1.8 95.2 0.2 1.6 0.4 0.2 0.0 0.4 26.3 4.8 54.6 0.7 2.3 1.7 7.2 7.1 1.9 21.4 0.5 0.8 SRPX2 SRPUL ENSG00000102359 "Sushi repeat containing protein X-linked 2" O60687 X 100644195-100675788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.8" "Cell type enhanced" "Detected in many" "Adipocytes: 20.9;Fibroblasts: 34.3;Granulosa cells: 21.6;Microglial cells: 37.5;Skeletal myocytes: 17.5;Urothelial cells: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 282.3;ASC TERT1: 116.9;HSkMC: 103.3;HUVEC TERT2: 72.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 2.8" HPA038786 Approved "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA038786: AB_10672724" "unprognostic (4.10e-2)" "unprognostic (4.55e-2)" "unprognostic (2.08e-1)" "unprognostic (3.72e-2)" "unprognostic (1.96e-1)" "unprognostic (4.21e-3)" "unprognostic (3.59e-3)" "unprognostic (5.41e-2)" "unprognostic (3.22e-2)" "unprognostic (1.26e-1)" "unprognostic (2.86e-2)" "unprognostic (2.29e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.84e-3)" "unprognostic (1.69e-1)" "unprognostic (8.67e-2)" "unprognostic (3.85e-1)" 31.8 7.5 3.6 6.3 4.5 0.2 20.7 1.3 2.6 11.3 8.5 7.1 1.2 6.0 0.9 17.7 7.1 3.1 12.7 2.8 5.8 13.9 5.4 13.8 0.4 4.3 5.6 8.3 2.9 0.7 2.5 9.3 3.1 6.3 1.8 0.1 4.6 3.8 3.4 3.7 5.1 4.4 2.0 12.9 4.5 1.1 7.4 0.3 4.3 4.8 1.2 16.8 10.9 2.5 11.7 1.2 2.9 0.1 282.3 116.9 0.0 26.3 19.8 8.0 25.1 1.4 17.6 0.0 1.1 15.9 7.5 0.7 0.2 13.1 8.6 0.1 0.1 0.2 0.9 2.8 29.3 0.2 0.6 103.3 0.3 27.8 0.9 24.6 72.7 0.0 0.0 0.1 27.1 0.0 0.0 0.0 3.4 0.2 0.3 0.0 2.5 0.0 11.4 37.6 0.4 0.0 0.0 0.8 0.2 6.1 0.3 0.1 36.7 13.8 12.3 10.3 0.9 0.1 0.0 0.1 18.3 0.0 8.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.5 1.3 2.6 2.8 5.8 4.3 5.6 3.1 2.0 7.4 2.5 20.9 0.0 0.6 10.1 0.3 0.4 5.0 6.5 0.6 0.0 4.8 1.8 0.9 0.0 13.7 0.0 0.0 0.2 0.0 1.9 0.0 1.6 3.6 0.6 11.2 1.6 0.0 0.0 0.4 0.0 0.4 34.3 1.1 0.4 0.0 21.6 4.6 0.2 0.9 0.0 0.2 0.1 4.1 0.3 1.6 2.7 15.8 0.3 0.0 37.5 0.0 0.0 0.0 2.0 0.1 0.8 0.0 6.0 0.2 1.6 0.0 0.1 15.5 0.0 0.0 17.5 14.6 0.2 0.1 0.6 0.4 0.5 0.3 2.6 0.4 49.1 SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 19.3;Fibroblasts: 27.0;Leydig cells: 18.0;Peritubular cells: 15.8;Skeletal myocytes: 32.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 26.9;BJ: 22.7;fHDF/TERT166: 27.5;hTERT-RPE1: 23.2;U-87 MG: 27.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Yes NA 88000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA042008: AB_10804124, HPA053316: " "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.28e-2)" "unprognostic (4.55e-2)" "unprognostic (6.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (4.26e-8)" "unprognostic (7.73e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-2)" "unprognostic (2.21e-3)" 13.1 2.2 2.6 3.6 4.6 0.1 8.8 3.0 2.1 23.0 1.8 33.6 1.9 39.7 3.9 5.7 17.0 12.9 17.6 1.8 2.1 3.6 1.7 9.1 1.3 3.9 2.6 14.5 1.8 0.3 17.6 1.9 4.0 8.8 2.8 1.1 3.4 12.8 3.6 5.6 8.7 20.1 2.2 11.1 9.8 2.6 3.6 2.0 3.8 2.8 0.5 10.6 15.9 2.1 0.1 1.4 0.5 0.0 3.3 26.9 0.0 22.7 5.5 3.7 4.6 0.4 0.0 1.2 0.3 27.5 1.1 0.0 0.0 0.0 1.9 0.1 0.3 5.6 1.5 0.0 5.2 0.1 9.6 12.3 0.0 5.4 0.0 23.2 0.0 0.7 0.2 0.3 0.6 0.1 0.1 0.5 0.9 0.0 0.2 0.7 1.2 0.3 2.5 0.0 2.9 0.4 0.4 0.0 0.5 0.5 0.4 1.2 7.9 1.0 1.3 1.1 3.8 0.4 0.0 0.1 27.8 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.6 3.0 2.1 1.8 2.1 3.9 2.6 4.0 2.2 3.6 2.1 3.5 3.2 0.6 4.2 0.3 1.9 0.3 0.3 0.0 5.3 0.8 1.1 2.8 0.0 0.1 0.0 2.1 0.1 0.4 0.8 1.9 0.1 0.6 1.5 19.3 3.3 0.0 0.0 1.5 0.0 0.1 27.0 2.0 0.9 0.0 0.5 2.2 0.0 1.2 3.3 1.1 0.4 0.0 1.0 3.8 1.3 18.0 2.0 1.8 2.8 0.7 2.1 0.0 0.0 0.3 0.1 0.3 15.8 0.3 0.3 4.6 0.2 0.7 1.9 0.0 32.1 6.8 0.9 1.1 0.4 1.8 0.0 0.5 0.9 1.4 0.2 ST6GALNAC6 "SIAT7F, ST6GALNACVI" ENSG00000160408 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6" Q969X2 9 127885321-127905408 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 258.8;Intestinal goblet cells: 100.6;Paneth cells: 178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "NK-cells: 23.7;T-cells: 25.6" "Cell line enhanced" "Detected in all" "ASC diff: 157.1" "Low region specificity" "Detected in all" HPA018890 Approved "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA018890: AB_1857531" "unprognostic (2.27e-1)" "unprognostic (5.23e-2)" "unprognostic (2.81e-1)" "unprognostic (4.54e-2)" "unprognostic (1.81e-2)" "unprognostic (5.71e-2)" "unprognostic (1.36e-1)" "unprognostic (4.84e-2)" "unprognostic (6.05e-2)" "unprognostic (1.40e-3)" "unprognostic (3.24e-3)" "unprognostic (3.31e-2)" "unprognostic (3.29e-1)" "unprognostic (1.10e-2)" "unprognostic (9.85e-2)" "unprognostic (3.46e-2)" "unprognostic (2.67e-2)" 95.8 37.4 155.5 21.4 156.0 17.7 68.7 129.5 177.8 48.7 120.2 75.5 9.5 48.6 50.0 35.0 67.2 28.4 61.3 165.6 130.9 50.1 63.5 66.7 27.5 133.4 137.2 83.0 52.8 32.4 26.0 22.0 128.3 40.2 126.4 16.0 28.3 41.5 46.0 37.4 35.2 38.0 128.3 64.1 43.9 17.6 140.6 14.9 32.5 40.2 23.1 56.6 42.6 134.6 12.0 9.2 18.9 36.9 157.1 91.9 7.4 29.7 69.6 43.7 35.9 16.3 10.0 13.8 13.4 68.1 28.4 21.9 25.6 23.7 19.0 50.9 14.0 13.4 19.0 16.7 48.1 3.3 18.9 94.9 27.5 34.0 15.1 61.6 40.9 11.9 12.2 14.6 54.9 9.9 8.4 19.3 9.1 12.3 17.5 24.6 27.0 14.3 32.2 2.4 13.1 21.3 21.4 8.8 7.6 12.3 9.3 29.0 26.7 27.6 16.3 30.5 15.8 18.4 9.8 21.5 24.5 4.1 8.7 3.3 1.2 0.1 25.3 1.9 18.5 5.3 16.5 18.8 1.8 3.9 10.0 13.7 0.6 23.7 5.0 2.1 25.6 12.4 155.5 156.0 129.5 177.8 165.6 130.9 133.4 137.2 128.3 128.3 140.6 134.6 1.3 3.2 4.3 13.1 10.5 23.2 17.2 15.7 9.1 22.0 0.9 0.6 8.7 8.6 9.5 0.0 6.2 4.3 11.7 258.8 0.0 0.3 2.5 0.8 1.7 20.6 38.5 26.1 11.5 0.4 7.7 26.6 3.6 1.4 7.0 0.2 46.8 28.5 11.6 25.2 10.7 100.6 18.3 10.0 35.6 9.4 66.5 4.1 24.9 8.4 3.2 58.7 46.4 5.5 3.8 0.3 178.3 60.9 8.9 20.5 0.3 0.0 16.1 8.5 85.5 41.2 31.9 1.4 4.8 10.3 26.9 3.6 17.7 0.5 84.7 18.6 STAT2 STAT113 ENSG00000170581 "Signal transducer and activator of transcription 2" P52630 12 56341597-56360167 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003858, HPA018888" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "Plasma membrane" "CAB003858: AB_562227, HPA018888: AB_1857550" "unprognostic (3.03e-1)" "unprognostic (8.59e-2)" "unprognostic (6.92e-3)" "prognostic unfavorable (4.75e-4)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "unprognostic (7.27e-2)" "unprognostic (1.93e-1)" "unprognostic (2.60e-1)" "unprognostic (4.12e-3)" "unprognostic (1.56e-1)" "unprognostic (7.45e-3)" "prognostic unfavorable (4.78e-13)" "unprognostic (1.88e-1)" "unprognostic (5.56e-2)" "unprognostic (2.77e-1)" "unprognostic (1.46e-3)" 17.3 6.3 2.6 19.2 2.3 7.8 10.3 2.7 3.1 18.7 2.9 10.7 10.7 11.3 5.6 11.1 12.9 20.1 8.1 3.1 2.3 8.4 20.6 22.8 19.6 4.2 2.0 17.4 9.9 12.4 8.6 15.9 3.1 10.3 12.5 5.6 18.1 9.9 4.0 7.8 13.0 21.8 5.9 25.2 10.3 4.0 4.6 19.9 10.7 8.4 20.1 18.4 5.6 6.2 15.5 8.5 11.8 12.5 98.3 58.6 26.1 19.4 94.0 92.4 93.1 8.7 16.4 17.9 22.6 38.6 24.2 14.9 21.0 15.1 18.0 13.8 4.7 27.2 7.6 9.3 58.8 5.0 20.2 86.8 13.4 19.5 22.8 70.5 25.6 14.3 15.2 44.7 35.1 9.4 7.3 3.5 5.2 15.1 9.8 6.9 22.1 17.1 21.3 18.1 4.2 10.1 31.5 18.8 43.1 22.7 16.4 17.7 11.2 22.2 10.7 8.0 3.1 32.5 32.9 9.8 30.3 7.2 9.9 14.8 17.2 11.3 7.7 22.8 7.9 5.2 7.4 7.7 11.6 7.5 5.2 5.1 6.8 4.8 18.3 10.2 9.8 13.1 2.6 2.3 2.7 3.1 3.1 2.3 4.2 2.0 3.1 5.9 4.6 6.2 36.0 12.8 41.7 40.5 24.0 14.3 10.3 13.7 17.1 17.0 17.4 15.0 11.1 15.7 24.4 18.4 20.9 11.2 28.1 23.8 1.9 14.0 13.8 20.7 36.4 26.5 15.5 8.6 29.8 10.7 24.5 27.6 19.9 26.6 10.1 24.6 27.8 64.8 25.9 3.3 28.6 16.8 6.1 50.9 25.6 43.7 19.6 45.2 32.0 24.4 42.3 10.4 18.6 27.6 111.8 11.9 21.9 17.3 24.4 11.4 24.0 10.7 24.2 21.8 26.3 20.3 22.5 3.2 5.0 12.5 14.5 11.1 20.1 13.7 14.8 13.2 STAT6 "D12S1644, IL-4-STAT" ENSG00000166888 "Signal transducer and activator of transcription 6" P42226 12 57095408-57132139 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001861 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol Nucleoplasm "HPA001861: AB_1080106" "unprognostic (3.43e-3)" "unprognostic (1.87e-1)" "unprognostic (1.37e-1)" "prognostic favorable (1.69e-4)" "unprognostic (4.14e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" "unprognostic (6.70e-2)" "unprognostic (1.88e-2)" "unprognostic (3.65e-1)" "unprognostic (5.39e-2)" "unprognostic (1.00e-2)" "unprognostic (2.81e-2)" "unprognostic (1.67e-1)" "unprognostic (1.55e-1)" "prognostic favorable (7.76e-4)" "prognostic favorable (1.14e-4)" 76.0 84.0 22.5 68.1 24.2 40.1 67.6 19.0 25.4 85.4 29.7 91.3 79.0 81.9 49.0 93.3 82.4 66.2 50.2 22.3 21.3 68.8 75.2 83.4 78.3 22.6 20.6 93.3 48.8 52.9 18.9 45.0 22.2 81.5 71.1 3.5 70.1 68.6 14.3 108.2 99.0 80.5 21.4 111.3 78.5 15.0 24.4 81.7 57.5 20.5 91.9 96.8 81.7 22.8 60.2 55.2 13.8 24.3 153.2 138.4 39.7 53.5 103.3 49.5 37.7 26.8 78.8 145.8 78.1 106.4 0.2 82.0 18.7 89.2 38.1 70.5 4.4 32.0 57.5 32.8 93.0 39.0 97.5 213.5 75.1 67.3 55.9 145.4 91.8 45.7 23.3 19.2 69.5 21.3 44.9 41.5 20.3 81.1 12.6 50.4 1.3 49.6 95.6 92.9 0.3 1.2 46.7 35.3 45.6 19.1 53.4 90.8 68.2 0.6 30.7 51.9 0.4 0.1 1.0 35.4 48.6 39.2 67.3 12.6 19.6 11.1 6.9 19.1 6.9 8.0 6.3 6.2 14.1 6.4 5.4 5.7 34.4 6.0 15.0 6.3 6.7 26.8 22.5 24.2 19.0 25.4 22.3 21.3 22.6 20.6 22.2 21.4 24.4 22.8 27.6 48.1 60.8 5.5 45.1 29.8 44.3 33.4 31.3 1.8 23.8 21.2 15.1 27.1 43.3 49.7 0.0 2.0 38.4 80.4 15.6 38.2 8.0 35.8 33.1 32.0 33.0 26.3 13.1 36.1 10.2 36.9 80.0 51.9 58.2 27.6 38.9 41.0 36.4 0.0 1.3 40.3 24.4 73.2 51.7 17.9 59.4 54.5 21.4 26.2 66.9 3.4 42.2 0.5 1.1 45.1 63.4 50.8 10.6 49.2 80.0 27.9 53.1 1.0 26.3 20.9 31.7 1.0 1.4 37.1 32.8 6.3 31.2 29.2 42.9 62.0 STK38 "NDR, NDR1" ENSG00000112079 "Serine/threonine kinase 38" Q15208 6 36493892-36547479 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004673, HPA038623, HPA051324" Uncertain Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB004673: AB_425892, HPA038623: AB_10967059, HPA051324: AB_2681442" "unprognostic (3.58e-3)" "unprognostic (1.80e-2)" "unprognostic (3.07e-2)" "unprognostic (6.76e-3)" "unprognostic (8.25e-2)" "unprognostic (1.47e-2)" "unprognostic (2.88e-3)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.44e-5)" "unprognostic (3.78e-2)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (1.98e-2)" "unprognostic (3.80e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (3.13e-3)" 27.6 11.5 13.2 28.9 13.6 30.6 23.2 15.8 18.1 23.5 15.2 40.4 24.0 21.3 12.5 39.6 21.4 20.7 24.2 14.2 13.4 23.1 24.7 24.9 34.5 14.4 13.4 16.0 12.5 8.3 14.4 21.7 13.6 23.8 36.5 11.3 33.6 16.0 16.1 30.6 41.6 27.4 13.0 34.6 23.2 13.8 14.8 28.0 14.0 16.2 33.8 30.0 28.4 14.2 43.0 31.1 32.1 34.8 63.4 47.9 27.9 46.7 37.6 47.6 47.4 24.0 28.7 57.3 35.3 70.0 39.5 44.7 26.9 19.6 55.7 23.6 23.0 41.1 40.8 21.9 31.2 15.8 21.7 31.9 50.0 36.9 23.6 54.5 30.1 28.7 34.0 32.4 68.5 25.7 25.5 40.8 13.4 50.5 27.3 97.7 38.9 15.3 45.0 52.9 37.4 17.7 57.0 25.9 34.0 35.7 27.8 40.8 29.4 38.4 33.6 30.9 30.7 27.1 51.4 39.9 8.7 60.1 37.8 91.2 45.2 34.6 57.0 49.5 44.1 22.4 46.9 50.4 29.1 16.2 41.1 45.8 59.4 59.3 73.3 14.4 48.7 58.3 13.2 13.6 15.8 18.1 14.2 13.4 14.4 13.4 13.6 13.0 14.8 14.2 29.7 19.2 16.0 27.4 25.7 13.5 9.6 21.5 21.1 3.0 16.0 14.5 15.5 18.6 47.9 7.3 0.0 13.8 59.5 47.1 1.9 18.9 9.0 15.3 16.0 18.4 14.4 16.6 46.5 12.7 17.8 22.2 34.7 20.4 13.3 13.5 12.1 15.0 13.2 5.0 34.2 25.4 22.4 38.2 20.3 5.3 27.1 40.1 17.8 57.1 48.7 7.6 101.0 38.2 36.8 27.8 30.8 30.1 39.6 12.8 32.8 16.6 40.4 7.7 13.1 8.3 14.0 26.5 10.3 31.5 21.2 15.3 45.5 10.1 28.4 27.9 STON1 "SBLF, stoned-b1" ENSG00000243244 "Stonin 1" Q9Y6Q2 2 48529383-48598513 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.0;Muller glia cells: 33.4;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;neutrophil: 1.0" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 23.7;ASC TERT1: 28.6;HSkMC: 36.1;hTERT-RPE1: 17.0;SuSa: 19.6" "Low region specificity" "Detected in all" HPA005715 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA005715: AB_1080113" "unprognostic (1.61e-1)" "unprognostic (4.44e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-4)" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "unprognostic (8.99e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.06e-2)" "unprognostic (2.50e-1)" "unprognostic (8.68e-2)" "unprognostic (2.49e-3)" 20.8 5.2 2.3 5.7 2.8 0.5 10.9 10.5 2.0 10.5 10.7 34.5 3.6 27.4 4.6 16.0 17.2 15.6 6.4 1.9 7.1 9.3 2.1 10.9 2.8 33.2 12.5 24.5 1.9 2.1 2.8 18.4 25.9 21.7 8.4 18.1 2.5 19.3 2.2 4.1 7.9 25.1 25.6 7.4 13.0 1.1 4.1 2.5 4.6 6.3 1.4 22.2 10.5 29.2 0.1 0.0 8.6 0.1 23.7 28.6 4.9 1.0 9.2 0.9 2.1 0.1 0.0 0.0 0.3 12.0 4.6 9.0 8.3 0.3 1.7 0.1 2.3 1.4 0.6 0.0 13.5 0.0 0.4 36.1 1.7 2.5 1.0 17.0 16.4 0.8 0.2 0.2 5.7 0.5 0.7 0.3 8.0 0.0 0.1 1.3 1.7 0.0 0.9 6.6 0.3 1.9 0.7 1.5 4.0 19.6 0.7 0.3 8.8 3.0 2.3 0.0 0.7 0.5 0.1 0.0 1.6 0.1 1.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.3 2.8 10.5 2.0 1.9 7.1 33.2 12.5 25.9 25.6 4.1 29.2 16.4 0.0 0.5 0.0 1.1 2.4 15.4 1.1 16.5 3.8 0.8 1.8 2.3 0.0 0.8 5.5 2.1 15.1 0.5 0.6 3.9 0.8 0.4 1.9 42.0 7.7 2.4 0.0 0.0 0.4 1.0 9.9 0.5 2.6 0.0 3.9 11.4 0.2 2.7 13.5 0.0 0.3 0.0 1.3 2.8 0.9 12.2 1.6 0.0 0.0 1.2 33.4 1.0 0.0 0.0 0.4 0.3 10.1 0.2 13.8 0.4 2.0 0.6 2.3 26.3 1.9 15.1 0.3 1.7 1.9 2.4 12.6 1.5 2.6 0.9 14.3 SUMF1 "FGE, UNQ3037" ENSG00000144455 "Sulfatase modifying factor 1" Q8NBK3 3 3700814-4467273 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 116.4;hTERT-RPE1: 117.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038025 Uncertain "Intracellular and membrane" NA NA 2800000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA038025: AB_10675624" "unprognostic (5.02e-2)" "unprognostic (2.30e-1)" "unprognostic (1.08e-1)" "unprognostic (8.99e-3)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (8.34e-3)" "unprognostic (3.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (2.65e-2)" "unprognostic (2.28e-1)" "prognostic favorable (4.79e-7)" "unprognostic (5.12e-2)" "unprognostic (2.58e-1)" "unprognostic (1.45e-1)" "unprognostic (7.86e-2)" 20.7 19.5 10.4 13.1 12.0 10.2 29.2 10.9 12.2 21.3 15.6 23.9 13.3 15.8 26.8 28.7 25.6 19.7 12.5 10.2 12.2 39.3 27.4 23.0 12.6 12.2 11.7 17.4 18.9 46.8 14.5 18.8 11.4 22.1 29.6 3.4 22.8 17.7 4.3 20.3 14.1 20.5 11.4 16.8 23.8 5.1 13.1 10.6 28.4 7.6 13.4 20.0 18.5 13.1 25.0 20.6 11.4 6.3 116.4 61.3 21.9 34.4 53.9 16.2 18.2 9.6 78.9 3.7 20.3 63.0 24.3 13.3 5.0 39.0 25.2 12.0 10.1 5.4 18.9 26.2 30.0 6.1 14.4 56.6 43.2 18.2 5.3 117.9 44.8 8.9 9.1 8.4 45.8 40.2 3.4 9.1 12.0 22.8 23.4 6.3 17.0 16.0 86.6 28.0 2.2 12.6 24.6 56.8 20.4 19.5 75.7 15.6 41.4 32.5 4.2 25.3 21.0 10.4 22.8 1.7 63.2 13.5 24.7 66.1 100.5 35.6 38.9 81.8 35.2 26.6 31.2 32.9 86.6 30.7 39.4 32.0 36.2 42.0 78.2 45.9 16.9 90.2 10.4 12.0 10.9 12.2 10.2 12.2 12.2 11.7 11.4 11.4 13.1 13.1 12.8 19.2 20.1 36.9 13.8 12.7 18.8 32.9 21.1 5.6 29.5 23.2 5.5 18.6 16.7 38.6 6.2 29.8 9.7 16.5 11.7 39.3 26.1 14.2 14.1 13.7 8.4 11.1 53.2 19.1 23.3 25.8 21.4 21.9 17.1 10.4 17.5 18.7 28.2 3.3 57.0 19.7 4.1 37.1 12.0 10.7 16.4 24.3 19.6 62.8 43.9 6.8 11.3 56.8 85.5 14.0 16.4 17.3 11.5 13.7 10.5 23.8 19.4 6.2 6.6 21.2 16.5 4.8 5.1 25.9 11.8 24.4 11.6 11.1 25.6 18.3 SVEP1 "bA427L11.3, C9orf13, FLJ13529, POLYDOM" ENSG00000165124 "Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1" Q4LDE5 9 110365248-110579880 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 38.6;placenta: 61.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 92.8;Inhibitory neurons: 50.3;Leydig cells: 42.0;Oligodendrocytes: 140.5;Syncytiotrophoblasts: 67.3;Theca cells: 34.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "ASC diff: 147.1;ASC TERT1: 84.7;BJ hTERT+: 62.3;HHSteC: 53.8;HSkMC: 66.7" "Region enhanced" "Detected in some" "cerebellum: 2.8" "Region enriched" "Detected in all" 5 "cerebellum: 20.8" "HPA020610, HPA021520" Enhanced "Intracellular and membrane" NA NA 160000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA020610: AB_2197021, HPA021520: AB_1855533" "unprognostic (4.47e-2)" "unprognostic (6.01e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.62e-2)" "unprognostic (9.13e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (3.31e-3)" "unprognostic (2.25e-1)" "unprognostic (1.51e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (9.84e-2)" "unprognostic (2.21e-1)" "unprognostic (1.55e-3)" 38.6 4.2 1.5 2.5 8.6 0.0 23.2 8.9 2.8 10.6 0.9 9.7 1.2 8.6 5.6 3.5 12.4 6.2 6.5 1.1 3.4 3.9 2.9 19.7 3.8 2.7 5.3 3.9 4.7 5.3 0.8 61.7 3.3 1.7 5.1 0.0 4.1 2.1 4.4 11.3 8.7 9.5 1.0 5.2 7.7 1.0 4.3 1.8 7.4 5.5 2.4 9.7 12.1 6.1 0.0 0.1 1.2 0.0 147.1 84.7 0.0 16.3 62.3 1.2 1.9 1.5 0.0 0.0 0.0 3.9 0.1 0.0 0.0 12.2 1.0 0.0 0.3 0.1 1.4 0.0 53.8 0.0 2.9 66.7 0.0 12.1 3.2 1.4 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.2 7.5 2.0 0.0 10.6 0.0 0.0 0.0 2.3 0.0 1.0 0.0 1.3 2.5 0.0 7.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 8.6 8.9 2.8 1.1 3.4 2.7 5.3 3.3 1.0 4.3 6.1 7.4 0.0 0.5 2.9 0.1 5.7 0.6 0.5 1.2 0.5 0.4 0.9 1.8 5.7 0.1 0.0 0.0 12.2 0.3 0.0 0.0 0.9 0.3 0.5 13.8 2.0 0.0 0.0 16.9 0.2 1.6 92.8 4.1 0.3 0.0 0.0 2.2 0.0 3.0 0.0 50.3 0.0 0.0 0.0 8.2 0.6 42.0 0.6 7.2 13.1 0.0 0.0 0.0 3.0 140.5 0.0 1.2 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 3.5 7.8 0.4 1.5 0.4 3.3 67.3 1.2 34.1 0.2 0.2 SYNE3 "C14orf139, C14orf49, FLJ25605, LINC00341, NCRNA00341, Nesp3, Nesprin-3, NET53" ENSG00000176438 "Spectrin repeat containing nuclear envelope family member 3" Q6ZMZ3 14 95407266-95475836 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 19.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 70.2;Cone photoreceptor cells: 62.6;Rod photoreceptor cells: 103.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 46.5;ASC TERT1: 36.2;Karpas-707: 42.3;REH: 34.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA055227, HPA077140" Approved Supported "Nuclear membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear membrane" "HPA055227: AB_2682747, HPA077140: AB_2686826" "unprognostic (4.63e-2)" "unprognostic (6.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.48e-3)" "unprognostic (7.15e-2)" "unprognostic (2.12e-3)" "unprognostic (2.45e-1)" "unprognostic (2.61e-2)" "unprognostic (4.92e-1)" "unprognostic (2.87e-1)" "unprognostic (8.50e-2)" "unprognostic (3.32e-1)" "unprognostic (7.41e-6)" "unprognostic (1.31e-1)" "unprognostic (1.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.19e-2)" 19.1 3.4 5.1 4.3 9.5 13.7 12.6 5.8 6.7 4.0 8.7 2.8 1.5 2.3 1.4 2.0 4.5 2.1 4.3 4.5 5.5 1.1 3.0 4.4 6.0 10.0 8.0 4.0 0.9 0.4 1.7 3.4 7.4 1.6 2.6 11.9 3.2 1.1 2.2 4.3 3.8 2.2 5.6 5.0 2.1 2.7 8.3 2.4 2.9 3.3 6.0 3.2 4.1 12.3 1.2 0.1 0.7 1.1 46.5 36.2 14.3 5.4 9.4 5.1 4.0 7.8 1.3 6.3 0.9 2.6 1.6 0.3 1.1 4.0 2.3 20.9 0.9 4.3 0.9 2.1 6.0 6.6 10.4 10.2 1.4 6.4 3.7 0.4 9.0 1.9 0.3 42.3 3.9 1.5 3.9 7.3 0.1 0.2 2.6 34.8 23.2 13.5 0.6 0.7 1.0 5.1 0.2 0.1 2.5 0.6 2.0 9.6 8.2 3.7 2.2 5.0 0.7 5.0 11.1 5.9 7.4 14.6 28.2 2.2 1.9 0.1 0.7 1.5 0.9 1.2 1.0 0.8 0.8 1.0 1.2 1.0 0.9 0.3 1.6 1.0 0.9 1.0 5.1 9.5 5.8 6.7 4.5 5.5 10.0 8.0 7.4 5.6 8.3 12.3 12.4 9.6 18.3 3.3 19.7 2.3 0.4 0.1 0.6 5.1 1.0 1.3 70.2 0.0 0.7 0.0 62.6 2.2 16.1 4.9 0.0 0.0 3.9 6.5 5.1 14.7 1.2 4.0 2.5 0.4 15.0 22.3 1.1 1.4 12.0 0.2 5.0 6.8 4.3 6.7 3.3 5.0 0.0 17.6 14.8 2.4 13.1 20.3 5.4 3.7 27.8 5.3 9.2 14.1 20.8 0.5 6.2 0.4 20.6 1.9 2.9 0.4 6.6 103.7 6.6 19.1 12.1 0.6 1.1 0.3 1.0 1.9 14.0 0.0 1.9 0.5 SYPL2 Mg29 ENSG00000143028 "Synaptophysin like 2" Q5VXT5 1 109466546-109482134 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "skeletal muscle: 363.5;tongue: 175.3" "Cell type enhanced" "Detected in some" "Astrocytes: 5.5;Cardiomyocytes: 10.6;Collecting duct cells: 3.7;Hepatocytes: 4.8;Late spermatids: 11.1;Proximal tubular cells: 5.1;Skeletal myocytes: 4.8" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 31.6;ASC TERT1: 13.2;BJ: 14.1;BJ hTERT+: 44.1;fHDF/TERT166: 23.1;HAP1: 11.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076657 Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA076657: " "unprognostic (1.82e-2)" "unprognostic (1.81e-1)" "unprognostic (2.90e-4)" "unprognostic (6.63e-2)" "unprognostic (1.35e-1)" "unprognostic (9.36e-3)" "unprognostic (2.84e-2)" "unprognostic (2.57e-1)" "unprognostic (2.35e-1)" "unprognostic (3.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "prognostic favorable (3.05e-4)" "unprognostic (2.54e-3)" "unprognostic (3.40e-1)" "unprognostic (9.46e-3)" "unprognostic (6.39e-4)" 2.8 11.7 1.5 0.6 1.5 0.0 1.5 1.3 2.4 4.0 4.0 6.2 0.5 6.6 4.5 4.6 1.4 0.9 19.9 1.6 1.3 9.6 9.5 1.3 0.5 1.4 1.3 3.0 5.1 5.8 1.1 3.2 1.2 3.1 1.0 0.4 4.2 6.0 363.5 0.7 1.6 6.0 1.0 1.1 3.2 9.3 1.6 0.1 8.0 175.3 0.3 4.1 2.4 1.3 0.0 0.1 0.1 1.8 31.6 13.2 0.0 14.1 44.1 4.3 1.6 0.0 0.1 0.0 0.0 23.1 0.5 0.0 11.8 0.0 0.9 0.0 5.1 0.0 0.4 0.2 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.4 0.1 0.1 0.0 1.4 3.3 2.3 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.5 1.3 2.4 1.6 1.3 1.4 1.3 1.2 1.0 1.6 1.3 0.2 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 10.6 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.2 2.8 0.0 0.1 0.4 0.0 0.0 0.3 1.3 0.0 1.0 0.0 0.0 0.0 0.9 0.0 4.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.0 0.1 0.0 1.0 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.1 0.0 5.1 0.0 0.0 0.0 4.8 2.6 0.4 1.4 0.0 0.0 0.1 0.2 0.4 0.0 0.0 TBC1D2B KIAA1055 ENSG00000167202 "TBC1 domain family member 2B" Q9UPU7 15 77984036-78077724 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 90.7;Theca cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041833, HPA048174, HPA052663" Approved Enhanced Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "HPA041833: AB_2732494, HPA048174: AB_2680297, HPA052663: AB_2681906" "unprognostic (3.13e-1)" "unprognostic (2.16e-1)" "unprognostic (8.25e-2)" "unprognostic (1.28e-2)" "unprognostic (3.94e-2)" "unprognostic (1.43e-1)" "unprognostic (5.07e-3)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (8.22e-3)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.23e-3)" "unprognostic (6.68e-2)" "unprognostic (3.07e-2)" "unprognostic (3.37e-1)" "unprognostic (3.19e-2)" 23.1 15.4 4.8 20.4 5.1 22.5 17.3 4.6 5.0 25.1 9.3 15.8 12.9 23.3 11.7 11.4 20.8 28.2 10.2 4.1 6.6 7.7 16.3 33.9 23.1 9.7 5.5 46.1 18.3 17.1 5.9 25.0 6.0 11.5 17.4 4.5 8.7 14.3 5.1 13.4 16.0 21.2 6.3 25.5 12.9 12.6 6.7 23.8 12.1 10.8 19.3 19.1 14.9 6.6 12.0 9.4 11.1 10.5 76.2 60.4 19.3 27.1 40.7 24.9 27.3 12.0 4.8 18.5 10.6 23.0 13.8 17.1 24.4 29.9 18.9 35.2 18.8 11.8 9.1 8.2 36.1 30.1 17.3 59.2 20.4 16.5 11.0 36.8 28.6 23.5 6.2 12.5 32.5 13.2 11.2 19.7 8.8 9.3 9.0 16.8 50.9 4.1 12.7 45.1 5.9 16.0 25.3 17.0 31.9 10.2 5.6 31.1 35.5 27.1 17.8 8.6 14.5 20.9 23.8 9.7 9.3 39.8 14.6 0.0 0.8 0.3 1.4 0.6 0.8 0.0 0.9 1.6 0.5 0.1 0.7 0.6 1.4 1.4 0.2 1.2 0.5 0.6 4.8 5.1 4.6 5.0 4.1 6.6 9.7 5.5 6.0 6.3 6.7 6.6 13.9 3.2 17.3 26.4 6.4 9.3 7.3 13.9 1.8 10.7 5.3 4.3 3.3 14.3 9.7 5.5 6.2 20.6 24.0 12.8 0.0 8.8 10.0 7.1 33.7 16.1 7.3 4.4 23.3 10.0 6.9 28.0 17.3 6.3 9.5 6.3 21.4 90.7 19.0 15.2 20.3 19.7 10.2 31.9 29.3 10.3 42.6 21.5 14.2 45.9 23.7 6.2 6.2 12.5 10.4 15.3 13.4 42.2 9.5 6.3 15.3 4.3 10.9 8.9 26.3 19.4 18.2 6.0 7.1 4.5 9.9 28.5 26.0 79.0 15.7 8.1 TBC1D8 "AD3, GRAMD8, HBLP1, VRP" ENSG00000204634 "TBC1 domain family member 8" O95759 2 101007228-101252866 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 30.1;non-classical monocyte: 38.2" "Lineage enriched" "Detected in many" 5 "monocytes: 38.2" "Cell line enhanced" "Detected in many" "ASC diff: 82.9;ASC TERT1: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015211, HPA037496" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nuclear speckles" "CAB015211: , HPA037496: AB_2675507" "unprognostic (1.82e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (4.25e-3)" "unprognostic (3.98e-1)" "unprognostic (2.12e-2)" "unprognostic (1.08e-2)" "unprognostic (2.74e-1)" "unprognostic (5.80e-2)" "unprognostic (2.38e-1)" "unprognostic (8.53e-2)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" "unprognostic (8.02e-2)" "unprognostic (1.26e-1)" "unprognostic (6.73e-2)" "unprognostic (7.98e-3)" 17.3 6.3 4.7 8.9 4.4 12.7 21.8 8.7 5.0 14.4 8.3 9.0 7.1 10.6 7.8 15.4 19.9 18.1 38.6 5.1 6.3 17.0 24.8 23.2 7.2 6.8 5.3 8.4 34.3 17.5 13.0 3.1 6.7 44.0 6.0 6.5 19.0 30.3 83.7 28.1 28.7 6.9 4.3 14.5 27.2 18.1 5.9 6.4 9.6 79.7 6.8 13.1 17.5 4.1 5.1 30.1 2.6 8.6 82.9 57.8 24.4 3.1 51.8 2.1 2.6 10.8 8.0 2.6 27.1 2.3 42.5 15.5 5.0 23.5 1.4 1.5 4.6 1.5 11.1 37.7 5.7 0.3 26.0 27.4 21.8 2.8 21.6 1.7 30.2 4.5 0.7 2.6 2.7 13.3 2.8 15.8 6.7 3.6 32.3 6.4 7.5 0.6 17.0 32.3 18.7 9.2 4.2 7.4 10.8 4.0 2.1 23.1 26.0 1.3 4.5 4.4 2.1 5.0 0.4 0.2 10.9 7.7 8.0 0.0 9.7 0.4 0.2 30.1 0.3 0.4 0.3 0.2 5.0 1.5 0.6 0.4 0.3 0.0 38.2 7.2 0.2 4.1 4.7 4.4 8.7 5.0 5.1 6.3 6.8 5.3 6.7 4.3 5.9 4.1 4.3 3.2 4.6 10.7 2.8 4.1 38.3 7.2 23.9 6.4 15.0 3.9 12.2 18.6 14.4 5.5 4.2 4.6 4.8 1.1 0.0 8.2 6.0 42.6 4.7 9.8 3.0 0.8 43.5 3.0 2.8 4.3 31.6 23.7 7.0 0.9 11.7 5.6 3.7 1.7 42.8 2.2 10.2 13.8 17.7 10.9 3.1 27.7 5.4 22.5 28.1 1.0 0.0 23.6 6.5 2.6 2.4 1.9 1.4 35.0 4.8 1.2 31.9 3.7 6.6 24.7 4.3 3.6 4.0 29.8 6.3 3.4 1.6 2.7 1.1 29.7 TBC1D8B "FLJ20298, GRAMD8B, RP11-321G1.1" ENSG00000133138 "TBC1 domain family member 8B" Q0IIM8 X 106802673-106876150 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 230.8;Alveolar cells type 2: 234.5;Club cells: 92.9;granulocytes: 113.0;Respiratory ciliated cells: 108.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023883, HPA027527" Enhanced Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA023883: AB_1857794, HPA027527: AB_2199395" "unprognostic (6.69e-2)" "unprognostic (1.06e-1)" "unprognostic (8.19e-2)" "unprognostic (4.69e-3)" "unprognostic (8.15e-2)" "unprognostic (6.97e-2)" "unprognostic (2.08e-1)" "unprognostic (1.88e-2)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (2.75e-1)" "unprognostic (4.89e-2)" "unprognostic (3.32e-2)" "unprognostic (4.77e-2)" "unprognostic (1.62e-1)" "unprognostic (9.97e-2)" "unprognostic (5.16e-2)" 4.5 19.6 5.8 4.2 11.5 5.2 4.6 15.3 19.6 6.9 15.0 6.3 7.8 5.4 10.0 3.0 3.9 7.0 3.4 8.0 5.1 8.4 12.0 4.5 2.7 2.0 1.5 6.4 9.0 8.6 6.4 4.5 3.6 6.8 7.3 9.6 7.7 6.4 3.1 4.1 9.5 5.1 0.5 3.2 11.0 8.5 5.9 1.6 8.8 1.6 2.0 4.5 2.5 24.4 14.7 4.6 1.8 7.1 21.9 30.9 7.9 16.3 16.9 2.8 8.5 8.1 12.6 5.1 12.9 16.6 11.6 7.6 5.9 8.2 7.2 2.5 6.5 7.1 6.4 7.7 5.7 1.8 2.6 13.7 6.5 6.0 2.9 17.2 7.9 4.1 2.4 8.3 10.0 7.4 4.6 2.7 9.2 21.6 7.3 2.0 3.9 2.1 7.9 10.7 3.3 2.7 13.4 9.7 6.0 9.1 11.0 2.2 10.0 10.4 11.2 13.9 6.0 7.6 8.4 1.3 20.2 1.5 13.1 2.1 0.8 0.4 0.7 0.4 0.5 0.7 0.6 0.5 0.2 1.4 0.4 0.5 1.9 0.5 0.4 1.0 0.2 0.1 5.8 11.5 15.3 19.6 8.0 5.1 2.0 1.5 3.6 0.5 5.9 24.4 7.0 230.8 234.5 1.0 2.2 2.4 7.8 8.4 7.4 4.1 6.9 3.3 2.6 4.3 92.9 7.3 4.2 2.8 0.6 9.5 7.9 8.8 0.9 4.9 12.5 19.2 4.8 1.3 8.3 9.3 3.0 25.2 21.9 6.8 113.0 4.8 3.3 13.5 1.7 0.0 7.5 15.1 6.1 2.2 0.4 2.2 9.0 12.7 3.6 14.0 1.0 1.8 1.0 13.6 25.4 6.1 9.2 8.6 0.2 8.0 14.0 12.1 108.3 3.6 0.0 8.3 5.7 3.6 3.2 3.5 1.4 2.6 9.4 31.4 10.1 10.3 TBX15 TBX14 ENSG00000092607 "T-box transcription factor 15" Q96SF7 1 118883046-118989556 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 46.8;skeletal muscle: 132.2;tongue: 114.7" "Cell type enhanced" "Detected in some" "Early spermatids: 8.2;Fibroblasts: 11.1;Hepatocytes: 15.3;Melanocytes: 7.2;Skeletal myocytes: 13.1;Smooth muscle cells: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 52.6;ASC TERT1: 22.1;BJ hTERT+ SV40 Large T+ RasG12V: 20.4;fHDF/TERT166: 28.2;HSkMC: 37.9;RH-30: 29.1;U-2197: 27.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.3" "HPA052245, HPA053713" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Centrosome "HPA052245: AB_2681771, HPA053713: " "unprognostic (1.94e-1)" "unprognostic (2.75e-3)" "unprognostic (1.92e-2)" "unprognostic (3.94e-2)" "unprognostic (5.72e-3)" "unprognostic (7.79e-2)" "unprognostic (5.82e-2)" "unprognostic (2.46e-1)" "unprognostic (3.00e-3)" "unprognostic (1.39e-1)" "unprognostic (3.81e-3)" "unprognostic (5.03e-2)" "prognostic unfavorable (5.57e-8)" "unprognostic (2.63e-2)" "unprognostic (3.90e-2)" "unprognostic (1.88e-3)" "unprognostic (2.31e-1)" 29.8 0.1 0.8 0.0 1.0 0.0 16.1 0.7 1.3 0.1 2.1 0.1 0.0 0.2 0.1 1.9 0.4 0.5 3.1 0.7 0.6 1.0 46.8 0.6 2.7 0.6 0.7 0.1 0.1 0.5 1.5 0.1 0.7 1.4 0.0 0.2 6.9 0.0 132.2 9.4 0.1 0.1 0.5 0.0 0.1 0.7 0.9 0.3 1.9 114.7 1.3 0.4 0.3 0.7 1.4 0.0 0.0 0.0 52.6 22.1 0.0 4.7 6.4 12.3 20.4 0.0 0.0 0.0 2.6 28.2 0.0 0.0 0.0 0.0 4.9 0.0 0.3 0.0 1.4 0.0 0.1 0.4 0.0 37.9 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 14.1 0.0 0.0 0.2 2.3 0.0 0.2 0.0 29.1 0.4 3.0 1.4 0.6 0.0 1.6 0.0 0.6 0.6 0.0 0.6 0.0 6.6 4.0 27.3 0.2 0.4 0.2 0.0 13.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.7 1.3 0.7 0.6 0.6 0.7 0.7 0.5 0.9 0.7 3.2 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 8.2 0.1 0.0 1.2 0.0 0.0 0.3 0.0 0.0 11.1 0.0 0.1 0.0 0.0 0.0 15.3 0.1 0.0 0.2 0.0 0.0 0.0 4.0 1.1 0.0 0.1 7.2 1.9 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.1 12.5 0.2 0.4 0.0 2.0 0.0 0.3 0.1 0.0 0.0 TEX46 C1orf234 ENSG00000227868 "Testis expressed 46" H3BTG2 1 23010834-23015852 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "testis: 83.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.11e-1)" "unprognostic (1.86e-1)" "unprognostic (9.04e-2)" "unprognostic (2.13e-1)" "unprognostic (1.24e-2)" "unprognostic (6.33e-2)" "unprognostic (2.84e-1)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (9.76e-2)" "unprognostic (8.12e-2)" "unprognostic (3.82e-3)" "unprognostic (2.29e-5)" "unprognostic (1.06e-1)" "unprognostic (1.15e-1)" "unprognostic (7.60e-2)" 0.1 0.1 0.4 0.0 0.7 0.0 0.3 0.3 1.5 0.2 0.0 0.0 0.1 0.2 0.7 0.4 0.2 0.0 0.1 0.5 0.5 0.1 0.1 0.2 0.0 0.6 0.6 0.1 0.2 0.1 0.2 0.0 0.5 0.2 0.0 0.7 0.0 0.0 0.1 0.7 0.0 0.0 0.3 0.0 0.0 83.2 0.7 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.1 0.0 0.4 0.1 0.9 0.2 0.4 0.0 0.1 0.3 0.2 0.0 0.2 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.1 1.1 0.3 0.1 0.2 0.0 0.2 0.6 0.2 0.1 0.2 0.3 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.4 0.1 0.1 0.1 0.0 0.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 1.5 0.5 0.5 0.6 0.6 0.5 0.3 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TGFBR3 "betaglycan, BGCAN" ENSG00000069702 "Transforming growth factor beta receptor 3" Q03167 1 91680343-91906335 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 143.9;Hepatic stellate cells: 322.7;Leydig cells: 146.3;Skeletal myocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 35.2" "Group enriched" "Detected in many" 18 "NK-cells: 16.6;T-cells: 35.2" "Cell line enhanced" "Detected in many" "ASC diff: 227.2;ASC TERT1: 108.4;RT4: 57.1;U-2197: 78.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008257, CAB018971" Supported Approved Cytosol "Secreted to blood" NA NA 50000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB018971: , HPA008257: AB_1080258" "unprognostic (7.57e-2)" "unprognostic (3.67e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.36e-4)" "unprognostic (9.39e-3)" "prognostic favorable (4.84e-4)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (9.32e-2)" "unprognostic (1.07e-1)" "prognostic favorable (4.99e-4)" "unprognostic (2.46e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.14e-4)" "unprognostic (1.08e-2)" 66.3 35.2 6.9 9.2 6.8 5.0 62.1 7.6 8.0 56.6 20.4 28.8 8.2 33.9 24.2 28.5 36.6 20.0 16.2 7.6 6.7 28.2 16.6 27.3 7.2 6.0 10.1 81.5 12.3 5.9 7.1 58.5 7.8 16.4 12.5 1.5 35.0 32.7 12.8 25.0 19.7 27.4 7.9 40.0 18.1 11.0 8.0 7.7 13.2 29.4 4.2 47.3 28.6 7.8 9.9 9.4 14.1 2.4 227.2 108.4 44.6 7.1 35.3 8.1 9.9 4.4 1.4 0.1 1.7 13.0 6.4 1.4 3.6 1.0 6.2 34.1 7.6 0.0 11.1 41.2 5.0 0.3 0.1 26.3 4.7 17.8 4.0 1.3 4.2 0.0 23.6 0.7 2.4 0.2 0.1 0.1 5.9 4.6 3.2 0.5 4.8 2.1 3.2 57.1 0.7 0.0 3.4 0.2 20.4 5.8 1.2 3.7 12.7 13.5 3.5 78.0 1.7 34.8 3.3 0.0 2.8 1.9 1.7 1.2 0.0 0.0 35.2 0.2 19.4 0.0 8.7 19.2 0.0 0.0 2.7 12.7 0.6 16.6 1.4 1.2 4.5 8.1 6.9 6.8 7.6 8.0 7.6 6.7 6.0 10.1 7.8 7.9 8.0 7.8 77.6 9.6 9.7 58.8 3.1 37.6 10.0 2.3 44.3 0.3 38.2 60.1 20.7 30.0 4.2 31.3 2.1 27.5 66.7 0.5 3.9 2.0 54.3 11.2 32.8 90.5 24.0 10.7 7.7 5.1 12.0 143.9 5.1 8.1 2.5 20.5 322.7 21.0 11.8 0.0 34.0 1.9 8.2 23.2 29.4 29.8 146.3 5.2 35.6 82.4 0.7 1.2 62.8 7.5 0.9 3.3 0.4 74.4 21.3 8.5 1.4 20.9 8.3 0.2 13.1 187.2 36.5 0.8 2.2 17.2 34.1 58.0 36.9 92.2 3.7 8.0 THAP8 FLJ32891 ENSG00000161277 "THAP domain containing 8" Q8NA92 19 36034984-36054739 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 18.8;Spermatogonia: 21.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA064056, HPA070139" Approved Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA064056: AB_2685184, HPA070139: AB_2686230" "unprognostic (1.33e-3)" "unprognostic (2.24e-1)" "unprognostic (8.03e-2)" "unprognostic (1.08e-2)" "unprognostic (3.10e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (9.01e-3)" "unprognostic (3.94e-1)" "unprognostic (1.27e-1)" "prognostic favorable (3.19e-4)" "unprognostic (2.50e-1)" "unprognostic (2.10e-2)" "unprognostic (9.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.48e-2)" "unprognostic (2.48e-1)" 3.3 3.2 9.1 2.5 9.8 0.9 2.7 9.4 9.6 5.0 6.3 9.5 3.7 4.7 3.4 3.7 3.8 3.5 3.5 8.3 9.7 4.1 4.6 2.8 3.1 10.1 9.8 3.5 2.8 3.7 3.4 2.8 10.2 3.6 2.4 4.6 3.0 4.3 10.2 5.2 3.5 4.4 8.9 3.4 3.6 9.7 9.7 4.0 3.1 3.3 2.2 6.6 4.0 11.2 3.3 8.2 4.4 3.7 11.6 8.0 2.8 2.7 4.8 5.5 7.8 3.6 2.3 4.5 9.7 4.5 5.7 1.5 2.5 3.3 2.1 3.2 1.6 2.8 3.0 4.3 12.7 1.6 2.7 6.2 5.0 3.8 2.6 6.2 2.6 8.2 2.4 5.3 5.8 5.5 4.1 3.4 3.9 5.6 3.1 3.9 1.4 4.2 4.5 2.9 8.1 6.1 4.6 3.9 3.3 5.7 4.1 2.2 2.3 7.3 4.5 4.5 2.2 5.2 4.5 3.3 8.0 2.6 4.7 7.1 6.5 7.9 5.2 7.6 5.9 4.1 5.5 5.4 4.7 3.0 4.1 6.1 2.7 6.2 6.6 4.5 5.8 4.1 9.1 9.8 9.4 9.6 8.3 9.7 10.1 9.8 10.2 8.9 9.7 11.2 1.4 3.2 3.7 3.6 3.4 1.1 1.2 3.2 2.8 2.2 3.0 2.4 3.7 5.7 2.9 7.3 2.1 10.2 3.5 2.1 1.9 5.7 3.0 1.5 3.9 2.5 6.6 1.3 2.7 0.5 5.5 3.8 4.1 2.7 5.7 8.8 3.9 3.5 15.8 3.3 3.3 1.3 12.2 4.4 0.8 6.1 1.8 3.2 1.8 1.9 4.4 5.2 8.2 4.5 5.5 2.6 2.7 4.1 2.5 1.2 5.3 11.7 1.2 3.0 0.0 1.7 2.9 18.8 21.5 2.3 2.3 10.5 2.5 5.8 2.2 1.0 THBS2 TSP2 ENSG00000186340 "Thrombospondin 2" P35442 6 169215780-169254050 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 86.8;Endometrial stromal cells: 71.1;Fibroblasts: 127.7;Langerhans cells: 69.8;Melanocytes: 56.9;Oligodendrocyte precursor cells: 40.7;Oligodendrocytes: 55.8;Smooth muscle cells: 33.7;Suprabasal keratinocytes: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 250.2;ASC TERT1: 200.3;BJ hTERT+: 88.6;BJ hTERT+ SV40 Large T+: 96.3;BJ hTERT+ SV40 Large T+ RasG12V: 117.8;HSkMC: 113.2;hTEC/SVTERT24-B: 127.2;U-2197: 107.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017716, HPA044304" Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 21000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB017716: , HPA044304: AB_2678891" "unprognostic (2.85e-2)" "unprognostic (1.41e-1)" "unprognostic (5.87e-2)" "unprognostic (8.90e-2)" "unprognostic (3.64e-2)" "unprognostic (8.73e-2)" "unprognostic (2.93e-1)" "unprognostic (5.10e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-2)" "unprognostic (4.00e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (3.77e-6)" "unprognostic (2.19e-3)" "unprognostic (4.38e-2)" "unprognostic (4.16e-2)" "unprognostic (2.48e-3)" 52.9 7.9 5.5 14.8 15.4 0.0 36.2 10.9 7.7 63.1 0.2 20.4 2.5 50.0 0.7 12.0 34.7 50.4 44.2 6.5 13.1 8.3 8.2 19.8 3.3 17.1 18.2 33.2 5.6 1.7 9.5 2.2 21.4 9.7 2.4 0.1 8.2 2.5 3.4 41.1 9.2 21.3 11.3 3.3 5.4 2.3 15.0 0.6 17.0 1.8 1.2 29.1 30.8 19.3 0.2 0.0 2.5 1.1 250.2 200.3 0.0 76.8 88.6 96.3 117.8 0.4 0.0 0.1 0.1 76.1 0.2 0.1 2.4 3.2 22.5 0.0 0.0 0.0 0.0 0.0 73.1 0.3 0.0 113.2 0.0 127.2 0.0 0.2 0.0 0.0 0.0 0.1 3.7 0.0 0.1 1.7 16.3 0.0 0.6 0.0 0.1 1.1 0.0 0.4 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.7 0.0 46.1 0.4 107.6 9.3 0.1 0.7 0.0 30.6 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 15.4 10.9 7.7 6.5 13.1 17.1 18.2 21.4 11.3 15.0 19.3 3.5 6.4 0.0 6.8 0.0 86.8 1.6 0.1 1.8 0.4 2.2 1.8 5.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.2 3.1 71.1 4.6 0.0 0.0 1.2 0.0 0.0 127.7 1.1 1.4 0.0 0.0 15.4 0.0 0.3 0.0 1.7 0.0 0.0 0.0 69.8 0.3 8.1 1.2 56.9 6.5 0.0 0.2 0.0 40.7 55.8 0.5 0.0 16.1 0.0 1.9 0.0 4.4 0.0 0.2 0.0 1.0 33.7 0.0 0.4 1.2 42.3 0.1 2.1 5.5 0.0 0.9 THRA "AR7, EAR-7.1/EAR-7.2, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRA3" ENSG00000126351 "Thyroid hormone receptor alpha" P10827 17 40058290-40093867 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 236.7" "Cell type enhanced" "Detected in many" "Muller glia cells: 95.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009654, CAB023349" Approved Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB023349: AB_619577, HPA009654: AB_1854603" "unprognostic (2.75e-2)" "unprognostic (2.20e-1)" "unprognostic (6.64e-2)" "unprognostic (4.22e-2)" "unprognostic (8.78e-2)" "unprognostic (1.64e-1)" "unprognostic (3.41e-3)" "prognostic favorable (1.84e-4)" "unprognostic (1.47e-1)" "unprognostic (5.47e-2)" "unprognostic (7.85e-2)" "unprognostic (2.65e-2)" "prognostic favorable (6.05e-8)" "unprognostic (3.05e-1)" "unprognostic (1.35e-1)" "unprognostic (4.21e-1)" "unprognostic (1.88e-3)" 40.7 43.7 199.1 12.0 236.7 23.0 38.9 159.3 218.3 67.5 108.5 67.2 31.1 49.9 22.0 19.1 57.7 25.8 63.8 189.7 181.8 34.1 10.2 32.2 9.7 162.4 172.1 90.7 31.3 29.9 50.0 17.1 149.4 34.5 18.8 35.4 27.3 35.5 90.7 50.2 36.2 34.6 166.5 13.9 48.0 18.7 183.6 12.8 32.6 52.8 6.3 45.0 45.9 179.9 4.9 37.6 11.5 28.9 77.4 28.2 4.2 19.3 23.0 19.6 18.2 31.5 27.2 5.6 31.3 37.6 8.7 11.4 22.6 11.7 10.6 2.1 21.6 10.4 44.5 13.4 26.0 16.9 11.2 45.1 9.5 18.4 7.1 45.4 26.6 16.7 21.2 5.2 16.5 7.1 22.8 27.4 10.6 24.6 11.8 32.1 22.7 27.6 6.4 3.3 19.5 17.7 14.8 23.3 33.7 17.5 27.3 19.5 18.7 19.4 18.9 17.7 5.9 11.9 9.0 3.4 12.0 19.1 10.6 0.2 0.3 1.9 2.0 0.1 0.8 0.2 0.8 1.2 0.3 0.4 1.4 1.7 1.1 2.1 0.3 0.6 1.0 0.7 199.1 236.7 159.3 218.3 189.7 181.8 162.4 172.1 149.4 166.5 183.6 179.9 32.2 19.2 7.3 27.1 6.2 10.6 28.1 3.3 31.3 76.4 19.6 21.2 45.4 38.6 2.7 33.1 20.9 0.8 16.5 37.9 50.9 12.3 1.1 20.5 29.5 20.8 25.1 17.9 19.1 14.8 1.4 36.8 29.0 12.1 14.0 23.1 24.7 13.8 11.6 62.2 24.2 22.6 6.1 10.6 5.1 2.7 51.6 8.6 19.6 8.4 5.1 95.2 37.0 15.6 26.5 6.9 14.6 49.7 3.9 17.2 58.8 29.9 7.5 22.5 19.7 84.7 44.4 0.3 27.3 14.6 10.4 0.3 18.1 16.3 39.9 13.8 THRSP "Lpgp, LPGP1, S14, SPOT14, THRP" ENSG00000151365 "Thyroid hormone responsive" Q92748 11 78063861-78068351 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 210.0;liver: 408.9" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 128.4" "Cancer enhanced" "Detected in many" "liver cancer: 44.1" "Region enriched" "Detected in single" 6 "cerebellum: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "ASC diff: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040642 Approved Approved Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm "HPA040642: AB_10794878" "unprognostic (1.19e-1)" "unprognostic (2.88e-1)" "unprognostic (2.84e-1)" "unprognostic (2.73e-2)" "unprognostic (3.07e-1)" "unprognostic (9.91e-3)" "unprognostic (1.59e-2)" "unprognostic (9.60e-2)" "unprognostic (1.07e-2)" "unprognostic (8.23e-2)" "unprognostic (1.68e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (9.64e-2)" "unprognostic (1.57e-1)" "prognostic favorable (3.28e-4)" "unprognostic (1.69e-3)" 210.0 5.9 0.1 0.4 0.1 0.0 95.3 2.7 0.3 0.1 0.0 2.6 0.0 0.1 0.4 0.3 1.0 3.4 18.6 0.2 0.0 4.6 408.9 0.1 0.7 0.0 0.2 0.1 3.6 15.5 0.1 0.0 0.4 0.1 0.2 1.5 48.9 2.3 8.2 33.7 4.6 0.5 0.0 0.1 0.7 0.1 0.0 0.2 5.7 3.3 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.0 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.3 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 2.3 21.1 11.2 0.1 4.3 0.0 0.0 0.0 0.0 0.2 0.0 9.8 0.0 0.0 0.6 0.1 0.4 0.0 2.7 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.1 2.9 128.4 0.0 0.0 0.4 0.3 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.1 THTPA THTPASE ENSG00000259431 "Thiamine triphosphatase" Q9BU02 14 23555988-23560271 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8;Spermatocytes: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028876 Approved Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Nucleoli "HPA028876: AB_10600731" "unprognostic (3.50e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (7.11e-2)" "unprognostic (2.25e-1)" "unprognostic (2.12e-1)" "unprognostic (4.13e-1)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.57e-1)" "unprognostic (4.47e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.70e-9)" "unprognostic (3.47e-2)" "unprognostic (2.32e-1)" "unprognostic (3.62e-2)" "unprognostic (5.40e-2)" 13.6 17.6 29.3 10.4 41.7 8.2 11.0 27.5 33.0 9.4 28.5 11.5 14.2 12.1 15.1 8.5 14.9 9.7 14.8 30.1 27.0 14.4 11.3 9.5 10.6 28.4 27.5 12.6 11.4 19.8 11.1 6.7 27.7 16.0 10.6 13.2 17.3 14.0 23.6 6.9 9.8 11.8 27.9 10.7 10.7 20.1 27.9 11.0 11.5 20.7 10.2 10.2 7.3 29.3 3.9 24.1 11.4 12.4 26.3 14.6 6.3 11.2 9.7 10.7 10.5 4.9 15.9 7.2 9.5 13.1 12.1 11.8 12.1 13.8 7.8 15.9 13.7 10.2 16.9 13.3 13.0 9.1 8.7 20.6 10.2 16.4 12.0 22.9 13.0 11.6 7.7 15.9 15.7 11.6 14.6 3.7 4.1 20.9 20.1 9.9 7.9 13.4 18.9 7.6 22.1 10.6 10.8 22.0 6.6 6.6 14.9 4.4 10.9 7.0 7.4 14.5 6.5 18.9 12.2 4.4 7.3 4.2 10.9 13.7 16.0 8.7 9.8 12.0 9.8 10.2 7.2 7.6 14.7 15.3 11.7 10.2 1.7 8.3 16.1 18.7 6.4 10.9 29.3 41.7 27.5 33.0 30.1 27.0 28.4 27.5 27.7 27.9 27.9 29.3 8.1 6.4 7.5 16.6 14.5 0.0 7.8 0.0 6.8 27.4 12.0 10.7 0.1 8.6 3.7 7.3 8.4 11.0 9.2 7.2 54.8 14.5 21.9 6.7 9.2 6.2 6.1 3.4 11.8 12.4 5.1 9.9 9.2 6.7 23.5 7.7 7.1 10.8 18.4 8.4 23.1 7.5 0.0 7.9 0.0 23.0 11.5 9.8 0.0 4.7 9.9 33.4 14.4 15.1 37.0 8.2 9.6 7.5 11.3 9.3 15.2 38.9 2.9 11.6 13.1 13.2 7.7 57.5 8.3 9.5 0.0 6.7 9.3 14.2 7.7 5.9 TIMP1 "CLGI, EPO, TIMP" ENSG00000102265 "TIMP metallopeptidase inhibitor 1" P01033 X 47582408-47586789 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 2277.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 2325.3;Hepatic stellate cells: 2681.5;Langerhans cells: 2307.7;Leydig cells: 1776.0;Macrophages: 1705.0;Peritubular cells: 1561.7;Smooth muscle cells: 2043.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 3225.4;ASC TERT1: 4323.2;fHDF/TERT166: 2762.5;HSkMC: 2960.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022360, HPA053417" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 127000000 520000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "CAB022360: , HPA053417: AB_2682142" "unprognostic (5.86e-3)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.09e-4)" "unprognostic (4.68e-2)" "unprognostic (1.81e-2)" "unprognostic (1.07e-3)" "unprognostic (4.99e-2)" "unprognostic (8.24e-3)" "unprognostic (9.12e-3)" "unprognostic (9.69e-2)" "unprognostic (9.10e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (2.90e-11)" "unprognostic (1.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (2.66e-1)" 1043.9 895.8 110.6 1713.4 110.5 122.2 253.0 114.1 329.6 630.5 160.0 228.0 68.3 342.1 237.4 130.8 570.2 1220.1 995.3 113.5 119.9 469.6 458.6 1221.2 150.4 132.9 125.2 820.8 170.1 224.1 510.7 589.3 130.1 749.1 204.0 25.9 518.6 412.7 61.8 132.4 180.0 741.1 118.9 239.9 208.9 267.7 286.5 80.3 340.0 78.9 119.7 2277.2 303.3 115.6 194.7 295.9 150.4 1850.9 3225.4 4323.2 36.4 2079.0 1728.4 632.5 514.0 118.9 360.1 1.8 269.6 2762.5 355.3 187.2 82.9 896.0 394.8 387.0 193.8 204.1 191.7 174.9 2097.2 136.6 2440.9 2960.8 227.7 1951.9 410.1 743.6 292.1 0.7 315.8 142.9 1088.6 343.1 2.5 518.0 166.8 229.8 647.9 2.5 318.3 173.8 1038.8 120.4 2.5 8.6 1243.6 8.2 276.9 277.6 15.3 257.6 284.8 943.7 1012.1 1108.3 206.3 58.8 135.0 7.4 2688.9 322.6 634.2 331.9 488.4 8.3 139.4 853.2 137.8 21.9 224.6 122.9 511.4 10.1 73.0 65.4 504.5 88.4 817.9 15.0 104.0 431.4 110.6 110.5 114.1 329.6 113.5 119.9 132.9 125.2 130.1 118.9 286.5 115.6 145.9 109.0 170.1 6.2 57.5 231.2 591.5 937.3 132.6 25.4 147.8 133.2 22.5 374.6 355.5 132.4 0.0 25.2 59.3 53.6 0.0 538.6 21.6 34.7 511.9 772.1 277.2 102.7 0.4 411.3 280.1 2325.3 53.5 66.7 491.4 163.7 2681.5 345.1 329.7 0.0 0.4 73.0 297.0 741.4 2307.7 86.9 1776.0 1705.0 512.3 6.5 289.0 141.7 73.2 8.5 0.6 802.1 42.4 1561.7 257.4 741.4 1.1 12.9 109.1 8.4 690.2 304.1 2043.5 52.8 10.6 25.8 174.7 45.0 126.5 231.9 50.5 513.7 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TIMP4 ENSG00000157150 "TIMP metallopeptidase inhibitor 4" Q99727 3 12153068-12158912 "Plasma proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 177.7;breast: 119.6" "Cell type enriched" "Detected in many" 10 "Adipocytes: 363.9" "Cancer enriched" "Detected in many" 13 "glioma: 66.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 212.9;ASC TERT1: 53.0;HSkMC: 91.9;NTERA-2: 50.7;U-87 MG: 53.6" "Region enhanced" "Detected in all" "cerebellum: 106.1" "Region enriched" "Detected in all" 9 "cerebellum: 47.7" "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.99e-2)" "unprognostic (5.14e-3)" "unprognostic (1.02e-2)" "unprognostic (2.10e-1)" "unprognostic (2.09e-2)" "unprognostic (1.97e-4)" "unprognostic (9.33e-3)" "unprognostic (4.26e-3)" "unprognostic (1.36e-1)" "unprognostic (1.74e-2)" "unprognostic (3.78e-1)" "unprognostic (6.81e-2)" "unprognostic (4.99e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (6.66e-5)" "unprognostic (2.86e-1)" 177.7 8.3 7.7 3.9 8.4 0.6 119.6 49.6 7.2 9.3 3.9 12.1 1.4 8.1 1.0 2.9 6.8 4.4 31.0 6.8 8.8 2.8 1.1 6.6 0.6 13.7 8.6 3.8 4.0 1.4 12.3 9.9 11.7 5.5 4.3 1.0 8.9 2.3 16.7 7.7 11.0 4.4 11.3 3.4 9.2 0.7 7.1 2.0 23.1 30.1 0.1 9.8 8.7 11.6 0.7 24.2 0.7 0.0 212.9 53.0 26.4 0.8 8.9 1.0 1.3 0.5 0.1 0.0 2.2 0.9 0.8 0.9 0.0 0.8 0.4 1.0 0.0 0.0 12.7 0.9 33.2 0.0 0.1 91.9 2.2 5.8 0.2 1.6 0.0 0.0 0.5 17.3 0.2 0.6 0.0 0.0 50.7 0.0 6.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 5.0 0.0 0.0 6.1 0.0 0.0 1.0 0.1 0.0 0.6 0.9 0.0 0.1 0.0 53.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 8.4 49.6 7.2 6.8 8.8 13.7 8.6 11.7 11.3 7.1 11.6 363.9 0.0 0.0 0.0 0.4 0.1 1.3 0.3 0.6 0.4 12.4 2.8 7.0 0.0 0.2 0.0 0.0 0.4 1.4 1.3 0.0 0.6 1.6 0.2 2.1 33.6 6.6 5.3 0.1 2.6 2.7 15.7 0.0 0.0 0.0 0.2 22.5 0.0 3.4 0.0 0.2 2.8 0.0 1.2 0.3 7.5 12.2 0.8 3.6 0.0 0.0 0.7 0.0 9.0 0.1 4.6 4.8 2.6 0.0 4.2 2.7 0.5 5.5 0.0 32.9 3.1 29.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 2.0 2.2 TK2 SCA31 ENSG00000166548 "Thymidine kinase 2" O00142 16 66508003-66552544 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041162 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041162: AB_10961178" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.27e-3)" "unprognostic (3.94e-1)" "unprognostic (2.93e-1)" "unprognostic (1.10e-1)" "unprognostic (4.83e-2)" "unprognostic (3.35e-2)" "unprognostic (3.45e-1)" "unprognostic (3.59e-2)" "unprognostic (2.85e-1)" "prognostic favorable (2.18e-6)" "unprognostic (3.05e-2)" "unprognostic (1.74e-1)" "unprognostic (2.71e-1)" "unprognostic (7.05e-2)" 48.1 30.2 24.2 11.8 27.6 8.5 25.6 24.7 25.7 20.0 19.7 15.0 10.9 16.2 29.3 12.3 19.0 21.1 19.2 24.1 25.6 25.1 37.3 18.7 11.7 26.5 27.8 26.8 24.4 38.0 22.4 15.1 27.6 19.2 12.7 11.7 22.6 19.9 11.5 12.7 13.5 18.9 27.5 23.0 15.7 33.9 25.8 13.0 25.6 14.6 9.9 17.8 15.4 28.3 13.3 26.5 12.1 14.5 64.3 52.2 0.7 22.0 22.3 15.1 16.8 6.5 26.4 0.1 23.8 63.9 19.0 11.8 5.3 17.7 10.4 8.5 6.2 4.1 17.2 12.9 45.1 5.6 9.2 39.4 15.3 18.5 26.1 62.5 19.9 13.1 6.8 28.1 37.9 4.1 5.5 14.9 5.9 5.1 15.4 7.0 21.0 28.1 44.1 12.5 4.4 8.9 63.2 6.1 26.9 6.6 9.6 16.3 29.7 30.8 15.9 26.3 7.6 30.3 12.2 11.6 38.9 5.7 18.4 5.6 9.4 6.0 1.8 5.1 1.2 0.1 1.3 1.0 8.7 1.7 0.6 0.9 8.5 2.7 4.3 1.8 1.2 2.5 24.2 27.6 24.7 25.7 24.1 25.6 26.5 27.8 27.6 27.5 25.8 28.3 25.0 22.4 9.3 19.6 7.3 5.7 5.1 5.8 12.5 15.5 15.4 11.4 8.0 17.2 7.5 22.0 22.9 10.0 7.6 6.0 9.8 15.7 25.2 15.2 23.2 14.4 9.6 10.3 10.1 22.4 6.0 19.9 11.7 13.0 24.8 20.6 31.1 48.9 21.7 21.9 12.0 6.5 2.0 55.6 10.1 40.5 23.3 23.6 10.6 10.3 22.6 18.4 12.3 14.6 19.4 28.9 3.3 19.2 12.4 4.3 14.4 45.9 9.0 20.5 0.0 14.4 10.6 48.9 11.1 9.6 3.8 2.9 8.6 22.2 7.6 4.2 TLCD2 ENSG00000185561 "TLC domain containing 2" A6NGC4 17 1702816-1710377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.3;Distal enterocytes: 112.4;Proximal enterocytes: 68.9;Skeletal myocytes: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 3.4;neutrophil: 1.6" "Lineage enriched" "Detected in single" 8 "granulocytes: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.0;HaCaT: 8.4;SiHa: 11.2;T-47d: 9.4" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 14.2" HPA046063 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoli "HPA046063: AB_2679520" "unprognostic (1.78e-1)" "unprognostic (6.71e-2)" "unprognostic (2.56e-2)" "unprognostic (1.20e-1)" "unprognostic (8.64e-3)" "unprognostic (1.64e-1)" "unprognostic (3.32e-1)" "unprognostic (4.04e-2)" "unprognostic (7.94e-2)" "unprognostic (7.74e-2)" "unprognostic (2.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.36e-5)" "unprognostic (3.77e-2)" "unprognostic (2.82e-1)" "unprognostic (7.79e-2)" "unprognostic (4.44e-2)" 10.3 9.4 0.6 1.8 0.7 2.1 4.7 1.6 0.9 3.0 2.3 7.3 6.0 1.8 1.2 4.7 2.7 1.8 2.1 0.6 0.5 1.8 7.0 3.9 0.7 1.0 0.7 2.5 1.2 1.0 1.1 1.5 1.0 1.9 5.3 10.5 2.9 0.9 1.7 2.4 6.9 1.2 0.7 1.3 4.7 0.6 1.0 0.1 1.6 0.8 0.8 3.1 3.5 1.6 1.0 1.1 1.1 3.5 8.1 9.0 0.3 1.9 1.8 1.0 0.7 6.9 3.1 0.1 1.9 3.1 1.0 8.4 1.5 0.9 0.7 0.2 0.7 0.9 2.4 0.3 2.3 0.1 2.4 7.6 3.2 1.2 2.2 2.9 0.7 0.1 0.8 0.4 0.9 1.9 0.1 0.4 0.1 3.4 0.6 0.1 5.3 0.2 0.7 2.7 0.2 0.4 11.2 1.0 1.6 1.5 9.4 0.8 2.6 0.5 2.3 2.1 0.5 0.1 0.1 0.1 0.6 0.3 1.0 3.4 0.2 0.4 0.2 0.1 0.1 0.2 0.3 0.1 0.0 0.4 0.2 0.2 1.6 0.3 0.1 0.2 0.1 0.1 0.6 0.7 1.6 0.9 0.6 0.5 1.0 0.7 1.0 0.7 1.0 1.6 19.0 51.3 55.5 0.3 1.6 0.0 8.2 0.0 4.0 7.9 5.8 9.5 2.7 17.2 18.0 11.0 129.3 4.9 2.0 112.4 0.0 7.3 1.1 12.9 10.4 14.1 9.0 11.2 0.5 9.6 2.6 14.9 20.9 13.3 15.8 3.9 18.9 24.2 5.5 0.0 0.4 24.6 0.0 6.5 0.0 1.8 13.4 10.7 0.0 3.7 1.4 11.7 0.0 0.0 0.1 13.5 40.1 5.7 3.3 6.3 68.9 1.1 19.9 57.8 6.6 124.2 17.8 0.6 0.8 9.1 0.3 4.0 5.1 5.4 35.7 13.0 TMEM100 "FLJ10970, FLJ37856" ENSG00000166292 "Transmembrane protein 100" Q9NV29 17 55719627-55732121 "Predicted membrane proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 192.5" "Cell type enhanced" "Detected in some" "Adipocytes: 57.8;Endothelial cells: 25.5;Fibroblasts: 40.7;Leydig cells: 40.7;Peritubular cells: 52.6;Sertoli cells: 32.9" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 28.9;ASC TERT1: 19.5;HHSteC: 44.8;HSkMC: 20.6;U-87 MG: 13.9;WM-115: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055936 Approved Uncertain Nucleoplasm NA NA "Cluster 19: Lung - Lung function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055936: AB_2682975" "unprognostic (1.35e-1)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (4.02e-2)" "unprognostic (6.78e-3)" "unprognostic (3.07e-1)" "prognostic favorable (2.67e-5)" "unprognostic (5.74e-2)" "unprognostic (1.87e-2)" "unprognostic (4.66e-1)" "unprognostic (1.89e-2)" "unprognostic (8.11e-3)" "prognostic unfavorable (1.32e-4)" "unprognostic (4.91e-3)" "unprognostic (1.12e-1)" "unprognostic (2.07e-2)" "unprognostic (1.26e-3)" 40.8 5.0 5.4 3.2 5.5 0.0 27.6 4.3 9.0 15.8 6.0 14.5 6.7 3.6 36.6 6.5 8.0 7.3 18.7 5.1 7.0 1.9 7.0 192.5 1.2 5.5 7.0 26.5 2.3 0.8 11.2 54.1 6.0 10.3 11.6 0.4 8.0 24.7 9.7 4.6 13.2 5.5 4.6 6.9 30.2 2.7 8.1 1.1 7.5 14.1 0.6 11.1 8.2 4.7 0.0 0.0 5.9 0.0 28.9 19.5 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 44.8 0.0 0.0 20.6 0.0 1.4 0.1 0.2 0.0 0.3 1.0 0.1 0.6 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 8.7 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.3 1.9 3.9 0.0 0.8 0.0 0.1 13.9 0.1 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.5 4.3 9.0 5.1 7.0 5.5 7.0 6.0 4.6 8.1 4.7 57.8 0.0 3.6 2.3 0.1 2.5 0.3 0.0 1.2 0.7 0.4 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.1 4.0 25.5 0.0 0.0 0.1 0.0 0.0 40.7 1.5 0.2 1.3 0.1 7.1 15.2 0.1 0.0 1.6 0.0 0.0 0.0 4.9 0.5 40.7 0.2 7.2 1.9 0.0 0.0 0.0 17.1 0.0 0.1 0.0 52.6 0.0 0.1 0.0 3.4 0.0 0.1 32.9 10.3 15.1 0.1 0.2 0.7 2.6 0.1 0.5 0.3 0.0 0.3 TMEM119 OBIF ENSG00000183160 "Transmembrane protein 119" Q4V9L6 12 108589851-108598320 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biomineralization, Differentiation, Osteogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 8.3;Fibroblasts: 30.5;Late spermatids: 9.3;Melanocytes: 8.8;Microglial cells: 15.0;Peritubular cells: 24.0;Smooth muscle cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 559.2;ASC TERT1: 152.6;BJ hTERT+: 168.0;fHDF/TERT166: 81.9;HSkMC: 238.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051870, HPA052650" Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA051870: AB_2681645, HPA052650: AB_2681901" "unprognostic (4.90e-2)" "unprognostic (2.66e-1)" "unprognostic (6.84e-2)" "unprognostic (5.97e-2)" "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (6.67e-2)" "unprognostic (8.40e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.61e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.29e-2)" "unprognostic (8.76e-3)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" 29.6 8.0 7.6 16.2 8.9 3.0 27.1 8.5 9.2 61.0 5.3 12.6 15.1 18.9 14.1 6.9 11.9 35.8 9.4 7.7 9.3 6.0 0.9 37.6 47.8 17.2 12.1 1.4 7.5 5.6 6.1 6.6 14.9 12.7 15.1 0.9 6.8 26.0 1.6 13.9 23.1 11.2 13.4 11.4 10.5 5.9 16.4 5.1 21.7 1.7 27.2 32.2 18.4 21.9 0.1 0.3 1.3 0.7 559.2 152.6 0.8 11.8 168.0 0.4 3.0 0.2 0.6 0.3 0.4 81.9 0.3 0.2 0.1 0.2 0.1 0.5 0.0 0.3 0.6 1.0 7.2 0.3 1.2 238.4 0.3 7.0 0.1 0.7 0.1 0.2 0.5 0.5 0.5 0.7 0.3 1.6 0.1 0.0 0.9 0.6 0.9 0.8 0.1 0.7 0.2 39.5 0.0 0.3 0.3 4.5 0.2 1.8 1.2 13.1 0.4 11.2 0.5 2.6 3.1 0.6 6.8 0.5 0.1 1.4 0.2 0.3 0.2 0.1 0.2 0.2 0.4 0.2 0.1 0.4 0.3 0.3 1.4 0.2 0.4 0.2 0.1 0.1 7.6 8.9 8.5 9.2 7.7 9.3 17.2 12.1 14.9 13.4 16.4 21.9 1.3 0.0 0.0 0.0 0.2 3.8 0.1 0.0 0.6 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 8.3 0.2 5.8 1.3 0.0 0.0 0.0 0.0 0.2 30.5 0.0 0.2 0.0 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 1.9 4.4 9.3 4.1 1.1 8.8 15.0 1.6 0.0 0.0 0.0 0.0 0.1 1.1 24.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 9.7 0.1 0.1 0.0 3.7 0.3 0.7 0.5 0.0 0.1 TMEM120A "NET29, TMPIT" ENSG00000189077 "Transmembrane protein 120A" Q9BXJ8 7 75986831-75994656 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 289.1;Late spermatids: 1002.1;Proximal enterocytes: 414.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 223.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.78e-2)" "unprognostic (3.35e-2)" "unprognostic (1.71e-2)" "unprognostic (4.03e-2)" "unprognostic (1.00e-1)" "unprognostic (1.99e-1)" "unprognostic (3.26e-1)" "unprognostic (2.75e-3)" "unprognostic (6.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (6.31e-2)" "unprognostic (1.02e-1)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (1.71e-1)" "unprognostic (5.15e-2)" 54.4 95.0 33.9 11.0 32.7 13.9 44.4 36.9 40.6 33.1 33.2 33.7 50.6 22.6 21.6 31.8 32.0 16.6 111.9 32.3 34.4 38.9 84.7 25.0 10.1 57.6 36.1 56.1 43.2 17.4 20.0 15.6 61.5 26.5 14.8 6.1 24.7 23.3 79.3 18.5 63.4 11.0 31.2 28.2 44.3 77.1 34.7 8.0 19.4 94.4 12.0 32.9 27.3 31.8 10.3 15.3 7.7 61.7 52.1 35.1 16.9 10.0 27.8 13.7 17.2 26.8 14.3 4.8 7.6 30.4 39.1 11.8 7.6 10.3 4.7 9.0 8.5 5.2 10.6 38.2 50.6 2.1 32.6 37.5 9.2 10.1 12.2 14.3 22.4 8.7 9.8 7.9 24.5 18.5 3.3 32.6 3.5 23.7 16.3 3.5 7.8 23.6 28.2 9.3 3.8 18.0 11.4 32.5 16.7 19.1 22.7 15.4 12.8 38.1 12.0 22.1 8.6 8.5 7.0 2.2 20.7 5.3 8.9 106.6 58.0 109.5 26.4 53.7 20.0 15.8 21.7 20.5 27.2 17.9 15.1 14.8 223.0 31.2 55.2 10.7 50.9 46.5 33.9 32.7 36.9 40.6 32.3 34.4 57.6 36.1 61.5 31.2 34.7 31.8 22.4 22.4 12.3 12.7 14.1 0.0 18.1 0.0 18.8 5.6 36.2 22.2 112.7 51.5 8.6 27.6 6.2 20.9 17.6 133.9 25.4 50.3 289.1 9.8 29.3 21.4 8.4 11.4 4.1 38.9 16.2 36.0 31.1 18.1 24.6 172.6 29.3 115.6 36.1 11.8 7.2 40.5 0.0 34.2 0.0 1002.1 40.4 36.0 0.0 3.7 23.7 12.8 18.6 4.0 7.3 40.0 108.9 30.9 24.6 17.4 414.8 118.0 4.4 7.0 39.5 46.0 31.2 113.4 15.4 33.1 0.0 10.9 20.0 31.0 43.6 28.1 TMEM132B "KIAA1786, KIAA1906" ENSG00000139364 "Transmembrane protein 132B" Q14DG7 12 125186836-125662377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 13.1" "Group enriched" "Detected in some" 8 "Astrocytes: 165.5;Excitatory neurons: 431.6;Inhibitory neurons: 481.5;Oligodendrocyte precursor cells: 268.9" "Cancer enriched" "Detected in single" 7 "glioma: 3.3" "Group enriched" "Detected in many" 4 "amygdala: 5.0;basal ganglia: 9.0;cerebral cortex: 13.1;hippocampal formation: 9.6;white matter: 6.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.1;HSkMC: 6.6;NTERA-2: 7.7;RPMI-8226: 3.5;U-138 MG: 11.8;U-937: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035661, HPA035662" Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA035661: AB_10669774, HPA035662: AB_2674726" "unprognostic (3.38e-3)" "unprognostic (4.39e-2)" "unprognostic (6.73e-2)" "unprognostic (6.33e-2)" "unprognostic (1.06e-1)" "unprognostic (7.46e-2)" "unprognostic (3.46e-1)" "unprognostic (1.26e-1)" "unprognostic (4.58e-1)" "unprognostic (1.12e-1)" "unprognostic (6.23e-3)" "unprognostic (1.29e-2)" "unprognostic (4.29e-4)" "unprognostic (1.20e-1)" "unprognostic (2.94e-2)" "unprognostic (1.06e-1)" "unprognostic (3.73e-3)" 0.1 0.1 5.0 0.1 9.0 0.0 0.1 0.0 13.1 0.6 0.0 0.9 0.1 0.5 0.7 0.4 0.2 0.2 1.1 9.6 1.3 0.1 0.0 0.0 0.1 0.2 2.0 0.1 0.1 0.0 1.0 0.1 0.3 0.4 0.2 1.0 2.2 0.3 1.2 1.7 0.3 0.1 0.0 0.0 0.3 0.5 0.5 0.0 1.9 0.3 0.2 0.3 0.6 6.2 0.0 0.0 3.1 0.0 2.2 2.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.1 0.4 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 11.8 0.0 0.0 0.0 0.0 0.2 0.0 1.8 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 9.0 0.0 13.1 9.6 1.3 0.2 2.0 0.3 0.0 0.5 6.2 0.0 0.0 0.0 165.5 0.0 1.1 0.9 0.5 1.2 5.4 0.5 0.4 3.0 0.0 0.5 0.0 6.2 0.0 0.1 0.2 0.0 0.0 27.1 0.5 11.8 0.4 0.0 0.0 431.6 0.0 0.0 0.8 0.0 1.0 0.0 1.4 0.0 0.0 0.2 1.7 481.5 0.5 0.0 0.0 0.5 41.0 0.3 0.2 1.8 13.1 0.0 0.4 0.0 268.9 18.9 0.0 0.0 4.5 0.0 0.7 0.1 0.1 0.3 0.5 0.0 1.4 0.2 1.2 4.6 1.3 3.3 0.0 0.2 28.4 0.0 0.4 TMEM132C "DKFZp761O2018, PPP1R152" ENSG00000181234 "Transmembrane protein 132C" Q8N3T6 12 128267403-128707915 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.6" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 217.3;Microglial cells: 160.2;Oligodendrocyte precursor cells: 580.6" "Group enriched" "Detected in some" 4 "glioma: 1.6;ovarian cancer: 4.6;testis cancer: 4.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "gdT-cell: 1.9" "Lineage enriched" "Detected in single" 19 "T-cells: 1.9" "Group enriched" "Detected in some" 7 "AF22: 3.7;ASC diff: 5.2;Daudi: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015633, HPA015984" Approved Centrosome,Cytosol NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Centrosome, Cytosol" "HPA015633: AB_1858089, HPA015984: AB_1858088" "unprognostic (2.29e-2)" "unprognostic (5.55e-3)" "unprognostic (7.34e-2)" "unprognostic (8.60e-2)" "unprognostic (2.37e-1)" "unprognostic (1.99e-3)" "unprognostic (5.48e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.85e-2)" "unprognostic (6.29e-2)" "unprognostic (7.97e-3)" "unprognostic (2.54e-1)" "unprognostic (5.71e-2)" "unprognostic (6.33e-3)" 31.6 2.7 8.3 0.3 7.6 0.0 14.0 6.8 7.3 16.8 15.5 1.4 0.3 5.4 3.8 3.1 11.8 1.1 4.3 6.7 7.4 0.4 0.1 1.5 1.1 9.3 14.4 8.6 2.7 0.1 0.7 2.5 8.7 2.4 0.4 3.6 1.7 4.1 0.5 2.0 1.8 1.0 6.7 0.3 1.2 1.3 9.6 1.0 0.9 3.4 0.4 4.7 9.2 6.0 0.0 0.0 3.7 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 7.6 6.8 7.3 6.7 7.4 9.3 14.4 8.7 6.7 9.6 6.0 1.9 0.0 0.0 70.2 0.0 0.4 0.0 0.0 0.0 18.6 0.0 0.0 1.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 1.1 0.2 7.6 26.1 1.0 0.0 0.0 32.2 0.0 0.0 6.3 0.0 9.8 0.0 3.7 0.0 0.0 0.1 0.0 217.3 0.1 0.0 0.0 1.1 0.2 9.0 0.1 1.8 160.2 0.0 0.4 0.0 580.6 42.3 0.1 0.0 15.1 0.0 0.0 0.1 0.1 0.0 2.3 0.0 0.8 2.5 0.1 0.4 0.1 0.0 0.0 0.3 0.0 0.1 0.0 TMEM140 FLJ11000 ENSG00000146859 "Transmembrane protein 140" Q9NV12 7 135148072-135166215 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 87.6" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 41.0;Plasma cells: 56.0;Syncytiotrophoblasts: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 358.4;eosinophil: 109.1;neutrophil: 429.1" "Lineage enriched" "Detected in all" 8 "granulocytes: 429.1" "Cell line enhanced" "Detected in many" "ASC diff: 77.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.52e-2)" "unprognostic (2.34e-2)" "unprognostic (3.26e-1)" "unprognostic (3.11e-1)" "unprognostic (1.79e-1)" "unprognostic (3.37e-2)" "unprognostic (9.72e-2)" "unprognostic (7.65e-3)" "unprognostic (3.41e-1)" "unprognostic (7.59e-2)" "unprognostic (5.20e-2)" "unprognostic (7.19e-2)" "unprognostic (2.35e-2)" "unprognostic (3.17e-2)" "unprognostic (1.83e-2)" "unprognostic (1.37e-1)" "unprognostic (1.05e-1)" 35.7 19.2 13.5 19.5 22.4 10.9 28.3 21.2 17.9 15.8 12.7 17.2 17.8 15.1 7.6 9.2 11.7 19.2 30.7 12.8 16.6 27.2 53.4 30.7 20.1 29.5 20.5 14.9 14.9 2.5 5.3 21.6 26.5 12.0 8.4 2.9 17.5 10.3 87.6 9.2 17.2 10.5 18.4 27.8 12.5 4.8 18.8 6.4 10.9 20.9 9.1 16.5 14.8 34.6 11.5 27.5 9.8 19.4 77.3 15.2 8.8 8.8 13.2 6.6 16.7 10.7 11.5 15.3 11.2 3.6 45.5 11.2 0.0 0.2 1.1 30.1 12.6 9.2 11.7 10.9 16.2 21.4 14.1 4.0 0.6 2.6 0.0 16.4 10.5 11.3 20.6 50.2 2.1 10.2 20.7 9.8 19.8 16.9 15.6 14.5 14.1 33.0 4.0 17.6 10.8 17.2 8.4 12.4 21.7 6.7 5.1 19.2 10.8 8.0 5.6 17.9 10.9 55.5 44.8 22.1 24.4 25.1 19.8 358.4 28.1 109.1 45.0 23.6 33.2 34.7 36.9 43.9 12.0 46.2 41.0 44.6 429.1 39.2 32.7 1.9 50.6 63.6 13.5 22.4 21.2 17.9 12.8 16.6 29.5 20.5 26.5 18.4 18.8 34.6 27.8 3.2 0.6 1.0 17.9 1.8 0.6 0.8 0.0 1.1 0.9 1.1 5.3 11.5 1.8 9.2 0.0 7.5 7.2 17.2 3.9 24.9 11.6 2.6 3.9 26.4 5.3 7.0 1.2 3.8 2.1 11.6 5.6 7.2 5.1 2.3 41.0 27.2 17.6 3.3 1.1 3.9 0.0 10.5 3.2 2.8 10.5 15.6 26.6 15.0 10.1 0.2 12.3 2.5 16.6 4.5 15.0 5.3 56.0 1.4 24.8 17.9 2.1 0.6 0.0 5.2 6.0 0.4 0.2 0.8 2.3 48.4 18.4 3.3 1.0 1.5 TMEM150A "FLJ90024, TM6P1, TMEM150, TTN1" ENSG00000168890 "Transmembrane protein 150A" Q86TG1 2 85598547-85603196 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 133.5;Early spermatids: 137.5;Proximal tubular cells: 85.0;Syncytiotrophoblasts: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 52.9;HHSteC: 49.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019015 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA019015: AB_2204758" "unprognostic (2.80e-1)" "unprognostic (1.62e-2)" "unprognostic (2.29e-2)" "unprognostic (1.42e-3)" "unprognostic (4.09e-3)" "unprognostic (5.65e-2)" "unprognostic (2.38e-2)" "unprognostic (1.42e-2)" "unprognostic (5.80e-2)" "unprognostic (2.64e-2)" "unprognostic (2.54e-3)" "unprognostic (7.16e-2)" "unprognostic (8.27e-3)" "unprognostic (2.09e-2)" "unprognostic (2.89e-1)" "unprognostic (1.37e-2)" "unprognostic (6.87e-3)" 18.7 16.3 10.0 5.2 10.8 1.2 17.0 9.8 11.1 16.3 11.1 21.0 6.5 17.7 6.3 11.0 17.1 10.4 15.5 9.7 10.3 32.8 38.5 19.3 6.0 11.9 10.7 17.1 37.9 8.0 11.7 22.4 10.9 17.4 4.1 1.4 14.9 10.2 53.7 9.3 12.9 11.5 10.6 9.7 20.6 24.4 11.3 2.5 14.9 27.2 4.2 22.2 13.1 10.1 2.7 5.1 6.3 9.3 52.9 23.7 15.3 5.2 9.1 4.3 2.0 23.6 7.1 0.8 19.8 15.3 8.0 2.2 6.8 13.7 2.0 1.2 6.7 1.5 3.0 39.9 49.6 0.4 4.7 28.5 18.4 7.0 9.9 20.6 15.2 1.0 14.0 1.5 17.5 11.9 0.4 6.9 11.5 10.8 5.1 4.1 0.6 15.8 13.4 10.6 1.0 3.9 5.4 35.4 13.5 5.9 8.7 6.2 12.6 5.2 4.4 4.5 1.8 10.6 2.8 5.2 8.5 6.0 2.3 0.0 15.2 7.2 5.5 17.9 6.5 5.3 6.2 5.6 12.8 8.1 6.9 4.2 0.7 8.4 15.1 7.6 1.5 6.0 10.0 10.8 9.8 11.1 9.7 10.3 11.9 10.7 10.9 10.6 11.3 10.1 24.1 9.6 14.9 10.7 9.0 4.5 15.3 16.0 10.2 6.8 15.3 12.7 5.2 12.8 16.2 14.7 0.0 133.5 10.4 3.5 29.4 16.9 137.5 5.0 9.0 14.9 3.0 1.7 3.9 14.4 18.2 14.3 5.6 6.0 10.2 5.2 15.7 19.7 37.9 3.3 5.0 5.2 16.2 10.3 13.1 64.8 19.9 14.6 10.6 9.4 15.2 6.5 7.2 5.5 5.9 12.8 7.0 24.5 5.9 20.3 16.4 85.0 8.3 3.4 13.1 14.6 11.7 2.4 5.6 7.9 3.7 146.0 7.0 9.2 7.0 13.1 TMEM175 MGC4618 ENSG00000127419 "Transmembrane protein 175" Q9BSA9 4 932387-958656 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057160 Approved Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear membrane" "HPA057160: AB_2683356" "unprognostic (3.84e-1)" "unprognostic (4.27e-2)" "unprognostic (1.28e-2)" "unprognostic (9.61e-3)" "unprognostic (2.43e-1)" "unprognostic (2.33e-3)" "unprognostic (1.12e-2)" "unprognostic (3.25e-3)" "unprognostic (1.22e-2)" "unprognostic (1.50e-2)" "prognostic favorable (9.85e-5)" "unprognostic (4.71e-2)" "unprognostic (5.08e-2)" "unprognostic (1.07e-1)" "unprognostic (3.74e-1)" "unprognostic (1.96e-1)" "unprognostic (7.51e-3)" 17.5 28.2 13.0 8.1 13.3 12.9 17.5 15.7 24.6 14.7 12.2 15.5 8.9 17.3 6.0 14.2 14.9 10.0 19.6 12.9 13.1 16.4 33.5 16.1 16.1 14.6 13.1 12.2 23.3 9.2 30.9 7.4 14.5 19.0 3.6 10.2 21.4 8.7 19.7 17.0 17.5 6.4 11.4 26.1 19.3 13.2 12.7 8.9 21.0 4.5 6.1 16.1 13.5 13.5 4.9 9.5 5.1 7.0 23.7 12.3 11.8 13.0 8.6 7.3 10.8 4.2 20.5 4.0 7.5 12.8 12.8 8.4 4.7 9.5 3.1 9.2 11.9 8.3 14.9 4.3 13.7 4.6 14.8 17.5 11.3 6.4 4.3 5.1 4.6 8.1 8.2 30.0 6.4 16.2 11.3 17.4 3.2 5.8 24.8 7.5 3.1 11.5 7.0 5.0 14.0 12.9 8.6 5.5 7.8 2.5 24.3 11.3 6.6 13.7 3.0 16.8 9.1 23.0 5.9 7.4 13.2 9.4 11.3 36.8 32.2 27.2 20.6 41.1 13.3 19.4 17.3 15.5 29.4 21.6 12.6 17.6 27.8 17.0 39.7 47.1 18.5 21.2 13.0 13.3 15.7 24.6 12.9 13.1 14.6 13.1 14.5 11.4 12.7 13.5 17.0 12.8 8.9 26.8 20.7 6.2 8.1 21.0 12.5 26.8 15.2 14.4 10.4 8.6 17.1 14.7 4.2 24.1 19.2 13.7 1.9 8.8 6.1 11.6 12.2 10.2 16.2 3.0 42.8 11.4 10.1 16.6 17.9 11.3 7.0 10.8 10.8 24.5 15.2 47.1 37.8 9.6 34.6 14.5 9.1 4.0 12.5 15.8 19.6 15.0 9.6 38.6 15.5 25.1 29.1 7.9 16.1 16.1 16.7 6.1 16.6 8.0 13.6 28.7 13.1 10.1 12.3 24.0 14.1 12.3 7.7 18.9 15.3 29.2 7.6 8.4 TMEM176A "HCA112, MS4B1" ENSG00000002933 "Transmembrane protein 176A" Q96HP8 7 150800403-150805118 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 377.7;liver: 1170.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 1043.9;Paneth cells: 779.4;Proximal enterocytes: 1294.5;Proximal tubular cells: 1103.9" "Cancer enhanced" "Detected in all" "liver cancer: 210.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 146.5;intermediate monocyte: 98.4" "Lineage enriched" "Detected in many" 5 "monocytes: 146.5" "Cell line enriched" "Detected in some" 31 "HSkMC: 730.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008770 Approved Approved Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA008770: AB_2256120" "unprognostic (4.70e-2)" "unprognostic (7.71e-2)" "unprognostic (5.71e-3)" "unprognostic (6.09e-2)" "unprognostic (3.96e-3)" "unprognostic (1.44e-2)" "unprognostic (2.51e-1)" "unprognostic (2.32e-1)" "unprognostic (4.19e-2)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (4.37e-2)" "unprognostic (4.79e-1)" "unprognostic (1.23e-2)" "unprognostic (1.98e-2)" "unprognostic (2.64e-1)" "unprognostic (4.91e-2)" 76.6 33.1 46.5 124.8 48.0 6.8 49.3 49.2 50.8 45.7 39.1 143.9 113.2 18.6 17.9 28.5 48.9 129.8 90.9 43.6 56.2 377.7 1170.6 58.5 85.6 64.0 56.2 104.7 29.8 3.9 11.6 66.6 58.2 26.5 151.3 20.6 24.2 15.9 6.4 20.6 203.1 50.2 61.3 51.0 48.7 6.1 49.9 15.5 21.3 17.4 66.0 98.0 54.5 63.9 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 3.5 14.2 0.2 0.6 0.0 0.3 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.3 730.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 23.3 0.0 0.0 2.7 0.5 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 146.5 12.6 0.3 98.4 0.4 2.1 0.1 0.2 30.9 0.0 0.2 0.0 1.8 0.3 46.0 2.4 0.4 53.3 46.5 48.0 49.2 50.8 43.6 56.2 64.0 56.2 58.2 61.3 49.9 63.9 15.8 0.0 5.2 3.9 9.8 7.4 0.4 0.9 5.2 56.2 40.6 63.8 24.9 118.7 10.9 200.5 4.2 0.6 2.0 348.5 152.6 64.6 0.3 4.9 14.8 20.5 74.1 6.6 0.0 27.2 0.6 185.3 17.9 2.5 29.0 29.9 23.2 1043.9 52.2 0.0 0.2 237.7 73.2 56.9 26.2 1.5 60.3 109.4 5.4 1.9 313.0 80.8 1.0 1.0 0.0 56.0 779.4 7.5 0.9 1.8 1294.5 1103.9 10.6 5.3 0.0 5.7 32.8 0.9 1.6 2.9 8.4 1.4 6.4 0.1 262.4 2.7 TMEM176B "LR8, MS4B2" ENSG00000106565 "Transmembrane protein 176B" Q3YBM2 7 150791285-150801360 "Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 1656.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 1171.9;monocytes: 502.3;Paneth cells: 762.4;Proximal enterocytes: 922.5;Proximal tubular cells: 976.5" "Cancer enhanced" "Detected in all" "liver cancer: 537.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 865.5;intermediate monocyte: 586.0" "Lineage enriched" "Detected in many" 5 "monocytes: 865.5" "Group enriched" "Detected in some" 17 "HSkMC: 642.7;THP-1: 215.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047509 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA047509: AB_2680072" "unprognostic (5.21e-2)" "unprognostic (7.86e-2)" "unprognostic (1.30e-2)" "unprognostic (8.27e-2)" "unprognostic (3.35e-2)" "unprognostic (6.96e-2)" "unprognostic (7.23e-2)" "unprognostic (2.74e-2)" "unprognostic (5.31e-2)" "unprognostic (1.47e-1)" "unprognostic (5.72e-3)" "unprognostic (7.50e-2)" "unprognostic (3.11e-3)" "unprognostic (5.56e-2)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.05e-2)" 120.9 49.5 48.5 190.8 50.1 13.5 77.8 50.7 65.8 74.5 43.0 251.8 167.7 25.9 25.7 50.4 81.5 197.3 208.5 45.4 58.0 356.5 1656.5 95.6 177.5 69.2 60.1 143.1 53.6 7.3 22.7 115.0 64.5 48.9 244.9 34.1 42.5 28.3 11.0 34.7 286.6 99.0 65.0 87.0 94.5 11.1 52.2 26.1 33.6 36.1 93.7 158.6 92.4 73.2 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 25.7 0.4 0.8 0.0 0.1 0.6 0.1 0.1 0.0 0.1 0.8 0.4 0.0 0.0 0.6 0.8 0.2 642.7 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.7 0.1 0.9 0.5 0.1 0.0 0.1 1.0 11.8 0.1 0.0 1.9 1.4 0.6 0.3 0.2 0.2 0.0 215.7 0.0 0.0 3.2 0.5 0.2 0.4 0.2 0.6 0.0 0.3 0.0 5.3 865.5 50.5 2.3 586.0 3.4 2.5 0.6 0.7 164.3 0.6 0.7 0.4 8.6 0.6 309.3 7.7 0.6 498.5 48.5 50.1 50.7 65.8 45.4 58.0 69.2 60.1 64.5 65.0 52.2 73.2 22.2 3.2 9.3 14.4 16.9 12.6 0.5 0.9 5.7 156.9 52.2 74.0 73.7 190.1 14.4 375.2 2.1 0.9 2.8 419.4 166.3 95.1 18.5 6.1 14.5 19.8 128.1 13.5 0.1 34.0 1.0 243.7 14.8 2.1 54.4 61.9 22.9 1171.9 92.5 6.7 0.6 252.1 46.8 98.5 44.4 12.2 43.5 190.0 16.0 8.4 502.3 87.3 1.0 7.5 0.1 65.4 762.4 3.4 1.5 2.5 922.5 976.5 11.3 17.9 0.0 6.7 34.0 4.0 3.8 1.8 15.6 2.7 9.1 0.4 263.7 2.8 TMEM179B ENSG00000185475 "Transmembrane protein 179B" Q7Z7N9 11 62787402-62790400 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016585, HPA062068" Enhanced "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA016585: AB_1844357, HPA062068: AB_2684676" "unprognostic (1.18e-2)" "unprognostic (2.83e-1)" "unprognostic (2.20e-1)" "unprognostic (1.78e-2)" "unprognostic (1.68e-1)" "unprognostic (6.11e-3)" "unprognostic (1.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.44e-1)" "unprognostic (1.25e-2)" "unprognostic (4.61e-3)" "unprognostic (2.76e-2)" "unprognostic (4.56e-1)" "unprognostic (1.64e-1)" "unprognostic (2.16e-1)" "unprognostic (5.74e-3)" "unprognostic (3.60e-2)" 52.1 60.3 32.4 22.0 34.7 21.5 55.0 33.7 36.4 50.5 41.8 48.7 34.7 44.4 71.2 47.9 46.7 28.4 34.0 30.8 32.9 54.3 64.3 51.0 26.9 35.3 33.3 39.6 58.7 34.1 31.0 30.0 35.6 45.8 40.1 10.4 59.1 26.4 27.2 58.2 49.8 26.3 33.7 48.1 53.9 41.6 33.0 33.0 55.4 21.6 29.8 43.3 46.0 36.9 35.6 68.8 17.7 35.7 136.3 34.3 22.6 38.2 47.5 29.8 34.2 39.3 82.9 16.5 53.1 78.0 44.2 64.8 33.4 35.4 23.2 48.6 44.9 24.1 29.2 36.3 90.8 30.9 32.2 65.8 55.8 57.1 70.0 60.0 30.3 46.9 33.2 46.3 34.5 81.1 40.2 59.5 26.5 76.8 74.6 26.5 28.8 86.1 57.7 42.6 24.4 26.7 49.3 65.3 70.4 35.8 76.2 37.8 42.2 39.6 29.4 73.3 32.2 51.2 32.5 22.6 57.0 19.0 47.3 302.9 300.4 332.7 149.4 305.0 147.9 169.2 135.5 144.9 198.2 140.6 118.2 117.3 224.3 140.2 305.9 366.1 146.6 282.5 32.4 34.7 33.7 36.4 30.8 32.9 35.3 33.3 35.6 33.7 33.0 36.9 119.6 60.9 59.2 15.3 52.7 68.7 73.9 175.6 86.0 12.4 108.0 122.2 1.3 65.8 121.1 60.7 0.0 174.5 71.7 91.2 37.2 138.1 5.8 75.2 54.5 83.7 65.2 40.4 9.9 149.0 160.5 76.8 54.6 66.5 54.6 43.8 69.9 81.9 133.2 8.4 9.0 103.5 128.1 63.7 83.0 11.0 75.8 76.5 106.7 12.2 98.3 74.4 91.6 16.1 28.1 124.0 137.1 45.9 93.9 97.1 179.4 87.5 122.9 14.7 65.7 50.5 57.8 120.8 100.5 93.2 76.0 185.1 60.0 90.4 94.8 97.5 TMEM196 MGC42090 ENSG00000173452 "Transmembrane protein 196" Q5HYL7 7 19719315-19773617 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 10.4;retina: 21.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 116.4;Endometrial stromal cells: 90.9;Excitatory neurons: 45.1;Inhibitory neurons: 23.9;Oligodendrocyte precursor cells: 127.6" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 4.8;ASC TERT1: 4.5" "Low region specificity" "Detected in many" HPA043163 Uncertain Uncertain "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Golgi apparatus" "HPA043163: AB_10794772" "unprognostic (6.08e-3)" "unprognostic (1.88e-2)" "unprognostic (2.14e-2)" "unprognostic (9.30e-2)" "unprognostic (5.63e-2)" 0.3 1.3 2.6 0.0 4.4 0.0 0.0 0.0 4.1 0.4 0.0 0.1 0.0 1.4 0.4 0.0 0.3 0.0 0.0 2.7 10.4 0.0 0.0 0.0 0.0 3.6 6.7 0.0 1.1 0.0 3.7 0.0 3.3 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.7 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.4 0.0 4.8 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.4 0.0 4.1 2.7 10.4 3.6 6.7 3.3 1.9 7.1 1.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 116.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 90.9 0.4 0.0 0.0 45.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 3.3 23.9 0.0 0.0 0.0 0.0 0.0 2.8 0.2 0.0 1.9 0.0 2.6 0.0 127.6 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TMEM204 "C16orf30, CLP24, FLJ20898" ENSG00000131634 "Transmembrane protein 204" Q9BSN7 16 1528688-1555580 "Predicted membrane proteins, Transporters" "Stress response" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 208.2;Endothelial cells: 95.9;Hepatic stellate cells: 133.2;Peritubular cells: 67.4;Sertoli cells: 118.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 156.6" "Lineage enriched" "Detected in many" 5 "T-cells: 156.6" "Cell line enhanced" "Detected in some" "ASC TERT1: 12.5;BJ: 16.5;BJ hTERT+: 21.2;fHDF/TERT166: 14.2;HHSteC: 36.9;HSkMC: 14.8;TIME: 12.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014028 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA014028: AB_2204906" "unprognostic (1.51e-1)" "unprognostic (6.35e-2)" "unprognostic (3.81e-3)" "unprognostic (2.36e-2)" "unprognostic (4.85e-2)" "unprognostic (1.81e-2)" "prognostic favorable (4.76e-4)" "unprognostic (1.65e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (8.44e-2)" "unprognostic (2.95e-2)" "unprognostic (4.04e-2)" "unprognostic (7.62e-3)" "unprognostic (5.11e-3)" "unprognostic (3.18e-2)" "unprognostic (1.60e-2)" "unprognostic (2.53e-2)" 48.6 20.9 15.1 7.8 13.4 0.5 43.3 13.2 16.3 36.8 11.0 28.4 6.5 35.9 4.0 12.1 26.9 12.9 70.4 11.8 12.2 45.9 17.2 71.5 16.4 13.8 14.3 17.5 15.8 7.4 14.6 12.8 15.1 28.3 2.8 0.5 16.8 14.4 18.0 18.9 25.3 11.2 12.1 24.2 22.1 8.2 16.1 7.9 49.0 16.1 5.4 28.8 20.7 11.7 0.1 0.1 0.9 0.1 7.5 12.5 0.2 16.5 21.2 2.5 2.6 0.6 0.1 0.1 0.1 14.2 0.0 0.3 0.0 0.0 1.1 0.1 0.1 0.0 0.8 0.2 36.9 0.0 0.0 14.8 0.0 0.0 0.0 0.0 6.7 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.3 0.0 0.2 0.7 0.0 0.2 0.0 0.2 0.5 0.3 0.5 0.1 1.8 0.4 0.0 0.0 12.6 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 4.4 0.3 0.7 0.0 24.5 0.9 45.2 0.6 80.0 55.0 1.8 1.3 156.6 82.2 2.8 34.1 0.8 0.6 38.1 41.1 15.1 13.4 13.2 16.3 11.8 12.2 13.8 14.3 15.1 12.1 16.1 11.7 208.2 0.0 3.7 0.7 4.5 5.7 7.1 17.1 1.2 0.2 3.4 4.4 8.3 0.0 1.6 0.0 0.0 0.5 6.5 0.0 0.0 0.3 0.8 1.9 33.6 95.9 0.0 5.7 0.7 0.2 0.2 31.8 0.0 0.8 0.0 2.3 133.2 1.1 0.4 0.0 0.6 0.0 2.0 3.8 5.7 1.3 23.6 5.6 7.2 30.0 1.4 0.2 12.3 0.0 0.6 0.0 0.0 67.4 0.5 1.1 0.0 0.1 0.2 0.8 118.3 3.3 43.0 0.0 0.2 0.7 3.1 0.4 15.3 17.2 0.0 5.1 TMEM260 "C14orf101, FLJ20392" ENSG00000070269 "Transmembrane protein 260" Q9NX78 14 56488354-56650606 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 39.8" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Excitatory neurons: 66.7;Inhibitory neurons: 62.8;Oligodendrocyte precursor cells: 69.9;Oligodendrocytes: 106.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003502 Uncertain Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Cytosol" "Focal adhesion sites" "HPA003502: AB_1078314" "unprognostic (4.63e-2)" "unprognostic (2.41e-2)" "unprognostic (1.98e-1)" "unprognostic (1.73e-2)" "unprognostic (2.51e-1)" "unprognostic (3.58e-2)" "unprognostic (2.04e-1)" "prognostic favorable (7.11e-4)" "unprognostic (7.14e-2)" "unprognostic (1.89e-1)" "unprognostic (1.95e-3)" "unprognostic (3.22e-1)" "unprognostic (2.23e-3)" "unprognostic (5.81e-2)" "unprognostic (8.11e-2)" "unprognostic (1.32e-1)" "unprognostic (3.84e-2)" 4.6 4.3 4.5 4.0 5.4 2.1 5.5 4.7 4.9 39.8 12.4 5.8 5.2 6.2 7.8 3.4 7.4 5.9 2.5 4.4 4.5 6.8 5.6 4.4 4.7 4.6 4.4 9.3 4.5 7.3 3.7 5.7 4.5 5.2 5.8 6.9 3.8 4.5 2.2 5.6 5.7 3.9 4.4 4.0 5.5 5.2 4.5 5.8 8.4 2.2 3.8 4.7 3.6 7.3 8.0 5.5 4.2 8.9 14.5 11.9 8.2 8.4 9.2 5.4 6.4 2.6 5.8 6.5 8.0 6.2 6.1 9.1 9.7 6.1 8.4 8.1 4.9 4.2 2.7 3.6 10.2 5.9 9.6 14.6 10.7 3.0 10.3 9.8 7.1 4.9 5.2 6.8 7.1 5.3 3.1 2.2 3.9 13.0 8.6 4.3 6.7 2.2 9.0 11.7 8.8 4.3 9.4 6.7 5.5 7.8 8.6 9.0 10.0 10.9 4.1 8.2 4.2 4.1 3.5 3.8 6.8 4.3 5.5 0.0 1.1 1.2 1.3 0.8 0.9 0.7 0.8 0.7 0.9 0.7 1.2 0.8 0.5 2.5 0.7 1.9 1.3 0.8 4.5 5.4 4.7 4.9 4.4 4.5 4.6 4.4 4.5 4.4 4.5 7.3 12.2 19.2 17.2 39.8 13.0 5.4 7.1 5.9 5.7 14.6 8.0 7.7 3.7 2.8 8.5 22.0 4.2 10.2 9.8 9.4 1.9 8.1 88.5 22.8 17.6 8.3 18.0 7.6 66.7 3.8 7.7 10.4 9.2 29.1 12.0 20.0 8.9 13.3 6.5 6.7 62.8 10.0 6.1 12.8 5.0 31.5 15.2 8.7 1.8 39.4 11.1 5.2 14.4 69.9 106.0 5.6 7.6 10.9 9.3 9.3 9.5 4.8 14.2 16.4 0.0 7.0 8.0 9.3 11.0 10.0 5.5 11.1 8.9 14.5 12.1 8.0 TMEM35B ZMYM6NB ENSG00000243749 "Transmembrane protein 35B" Q8NCS4 1 34981535-34985353 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 22.4;Alveolar cells type 2: 13.4;Club cells: 6.2;granulocytes: 8.8;Respiratory ciliated cells: 15.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 115.3;CAPAN-2: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051024 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 44: Non-specific - Transcription" "Cluster 5: Breast - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli" "HPA051024: AB_2681316" "unprognostic (3.34e-3)" "unprognostic (2.77e-3)" "unprognostic (4.25e-1)" "unprognostic (2.12e-2)" "unprognostic (5.52e-2)" "unprognostic (2.08e-2)" "unprognostic (2.06e-1)" "unprognostic (4.31e-2)" "unprognostic (1.06e-1)" "unprognostic (7.51e-3)" "unprognostic (2.32e-1)" "unprognostic (9.41e-2)" "unprognostic (2.03e-2)" "unprognostic (1.86e-1)" "unprognostic (5.49e-2)" "unprognostic (4.53e-3)" "unprognostic (1.07e-1)" 48.9 36.0 12.6 25.1 12.5 13.6 40.1 12.4 18.5 41.6 16.9 27.4 16.6 36.2 39.0 15.4 41.3 41.0 32.3 12.4 13.1 36.8 40.1 44.2 40.0 13.8 12.8 32.5 29.6 29.8 21.8 63.4 13.7 30.4 26.6 2.2 25.8 34.8 8.6 13.3 27.6 30.1 13.7 32.5 24.4 22.6 13.4 29.7 44.7 20.4 30.9 36.2 33.3 14.4 25.8 19.5 4.2 7.3 115.3 67.1 9.3 27.7 46.2 19.1 25.8 19.4 113.1 12.6 42.1 28.4 30.3 27.2 8.1 23.4 15.0 49.2 12.9 27.2 9.0 23.1 63.2 18.0 27.5 67.7 21.3 17.4 36.6 39.1 38.3 26.8 17.5 36.2 34.2 16.2 13.3 18.6 20.2 0.0 13.6 17.7 37.3 4.0 53.6 24.9 11.1 3.5 42.4 0.6 39.5 21.3 10.3 27.9 39.4 25.6 24.0 22.7 15.8 20.9 12.7 8.9 25.7 29.4 22.2 161.3 101.2 112.4 188.7 118.6 202.9 108.9 205.0 208.3 71.3 89.9 177.7 179.9 31.4 165.4 100.4 159.5 232.4 182.9 12.6 12.5 12.4 18.5 12.4 13.1 13.8 12.8 13.7 13.7 13.4 14.4 0.6 22.4 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 6.2 0.0 0.0 0.1 0.2 0.0 0.0 1.0 0.0 0.3 0.7 2.1 0.0 0.0 0.0 0.2 0.2 2.0 0.0 0.3 8.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 15.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 TMEM43 "ARVD5, DKFZp586G1919, LUMA, MGC3222" ENSG00000170876 "Transmembrane protein 43" Q9BTV4 3 14125015-14143680 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cardiomyopathy, Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 137.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019198 Approved NA NA 34000 "Cluster 5: Granulocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA019198: AB_1858118" "unprognostic (3.65e-3)" "unprognostic (2.52e-1)" "unprognostic (4.03e-2)" "unprognostic (4.66e-1)" "unprognostic (5.45e-3)" "unprognostic (1.72e-1)" "unprognostic (1.28e-3)" "unprognostic (1.08e-1)" "unprognostic (2.57e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.77e-2)" "unprognostic (5.45e-2)" "unprognostic (1.35e-3)" "unprognostic (2.19e-1)" "unprognostic (9.78e-2)" "unprognostic (1.18e-1)" 75.4 34.3 23.1 36.8 23.8 21.0 61.3 23.0 25.3 66.8 23.5 56.7 23.5 89.1 31.0 69.5 63.9 47.1 64.7 23.2 25.0 27.7 19.6 58.1 30.2 27.5 25.1 82.6 27.3 25.6 30.6 57.6 25.9 43.3 29.4 15.9 37.9 65.2 60.8 108.7 40.0 82.5 23.6 31.2 34.8 15.2 25.5 26.0 47.0 45.8 33.7 56.1 66.4 25.2 41.5 45.7 44.1 58.3 173.4 180.6 104.6 80.1 164.8 129.9 93.0 37.5 54.1 19.5 55.7 201.3 64.3 88.3 47.1 70.9 92.9 48.7 38.0 35.3 45.6 53.8 109.3 51.4 40.4 136.0 173.6 107.9 133.0 103.6 94.8 36.2 56.1 47.8 76.6 54.3 23.4 43.2 48.4 62.8 75.3 32.2 46.8 78.2 59.4 70.4 12.9 35.5 101.0 59.3 66.5 37.3 37.5 74.3 86.4 118.7 63.7 120.6 76.0 32.1 54.3 25.1 89.3 68.4 108.7 81.3 51.5 100.3 68.7 45.5 64.0 36.8 66.8 62.7 67.4 31.6 44.5 49.0 157.2 79.9 49.2 42.6 65.7 69.7 23.1 23.8 23.0 25.3 23.2 25.0 27.5 25.1 25.9 23.6 25.5 25.2 44.2 137.8 46.8 17.9 16.8 43.7 32.2 31.0 39.9 6.2 19.9 29.7 13.4 15.7 52.9 18.4 14.6 31.2 43.2 9.3 0.0 34.9 0.6 17.3 58.1 37.4 4.9 22.5 24.1 10.0 65.6 68.0 20.9 34.4 28.4 16.1 23.6 8.9 17.8 6.7 20.6 8.3 8.2 16.1 33.5 3.9 43.2 19.8 30.2 15.9 26.8 8.4 16.5 30.2 23.9 22.4 9.7 70.7 15.6 35.8 8.8 9.0 16.2 8.6 32.9 43.6 39.3 5.6 12.0 44.1 45.5 37.5 32.1 17.6 11.5 30.2 TMEM45A "DERP7, FLJ10134" ENSG00000181458 "Transmembrane protein 45A" Q9NWC5 3 100492619-100577444 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skin 1: 475.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 425.3;Club cells: 841.5;Early spermatids: 207.3;Suprabasal keratinocytes: 254.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 406.9;ASC TERT1: 118.3;HSkMC: 125.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA062101 Uncertain Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "HPA062101: AB_2684682" "unprognostic (5.92e-3)" "unprognostic (5.44e-2)" "unprognostic (2.11e-1)" "unprognostic (1.43e-3)" "unprognostic (7.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (2.37e-1)" "unprognostic (2.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.18e-11)" "unprognostic (1.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.02e-5)" "unprognostic (2.68e-2)" 19.4 18.1 1.4 11.7 3.3 2.0 42.8 1.7 2.5 38.4 2.3 10.3 3.6 18.3 3.2 16.5 20.9 18.9 21.9 1.5 1.8 3.7 99.0 13.1 2.6 1.9 1.9 11.9 23.3 2.7 22.9 40.9 1.8 9.1 6.6 1.7 26.9 6.3 3.2 475.1 6.4 25.4 1.7 5.0 7.0 13.3 1.9 1.6 9.1 2.5 50.7 19.5 79.5 2.1 28.6 2.0 2.7 9.6 406.9 118.3 0.3 66.9 62.0 9.4 84.8 2.5 0.6 0.0 32.6 44.1 24.6 31.9 2.4 13.0 23.4 7.2 8.4 23.9 9.3 8.0 25.7 0.4 1.5 125.4 7.4 17.1 25.4 39.0 3.5 0.0 0.6 3.2 22.6 0.3 0.1 0.7 3.2 0.0 16.8 0.0 23.3 0.4 0.6 1.0 2.9 19.4 16.4 8.5 7.3 18.2 0.8 13.6 9.3 62.9 44.3 0.5 15.2 53.8 32.9 0.1 49.7 1.9 42.6 0.0 0.9 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.0 0.6 1.4 3.3 1.7 2.5 1.5 1.8 1.9 1.9 1.8 1.7 1.9 2.1 1.6 60.9 61.4 0.7 3.0 94.6 5.4 425.3 9.6 3.2 19.1 8.9 2.5 1.5 841.5 0.0 0.0 2.6 0.4 0.2 0.0 7.5 207.3 3.0 79.1 8.9 1.2 1.3 0.8 14.9 46.3 56.3 2.0 2.0 65.0 10.7 15.0 137.1 5.8 8.4 2.4 2.0 63.1 6.5 25.4 25.4 16.1 6.6 23.2 13.1 1.1 3.5 0.0 16.1 11.8 6.5 2.6 27.8 26.8 3.1 0.3 0.2 121.0 0.9 6.6 22.8 56.6 1.5 3.3 5.4 254.9 7.5 6.4 26.7 0.1 4.4 TMEM50B C21orf4 ENSG00000142188 "Transmembrane protein 50B" P56557 21 33432485-33479974 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034199, HPA068995" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoli fibrillar center" "CAB034199: AB_2205160, HPA068995: AB_2686066" "unprognostic (3.22e-1)" "unprognostic (5.93e-2)" "unprognostic (7.82e-2)" "unprognostic (6.14e-2)" "unprognostic (1.26e-1)" "prognostic favorable (3.00e-4)" "unprognostic (2.24e-2)" "prognostic favorable (3.33e-4)" "unprognostic (8.65e-2)" "unprognostic (3.36e-2)" "unprognostic (1.85e-2)" "unprognostic (3.54e-2)" "unprognostic (9.58e-3)" "unprognostic (3.41e-3)" "unprognostic (8.28e-2)" "unprognostic (3.47e-3)" "unprognostic (3.32e-3)" 23.4 26.9 17.3 15.5 13.4 9.3 26.4 13.8 20.3 25.3 22.8 20.8 22.4 22.1 55.1 19.9 27.4 29.5 24.7 13.4 15.5 36.0 15.6 24.2 15.4 14.9 20.7 33.6 12.3 35.1 15.0 17.0 16.1 30.8 19.9 28.2 15.8 48.8 19.9 14.5 21.2 22.1 15.0 16.0 23.2 16.0 22.6 13.8 89.3 22.1 15.1 29.7 15.7 14.3 25.7 5.7 10.4 15.5 55.7 40.4 5.4 20.5 27.4 16.8 10.8 6.3 22.9 14.2 21.6 20.3 21.2 10.6 14.2 14.4 12.2 17.3 11.9 28.5 4.0 13.9 25.4 20.7 17.6 20.3 14.0 13.0 10.2 28.4 20.7 15.4 20.1 28.9 21.8 15.9 15.6 21.9 4.6 45.5 5.3 7.9 19.6 25.0 30.4 17.8 8.9 12.1 23.7 29.2 24.5 6.1 34.0 26.7 18.0 11.2 9.1 15.5 8.3 29.4 49.7 18.9 10.5 31.4 19.9 14.7 18.3 43.6 18.1 19.6 18.5 13.4 22.0 20.8 24.8 17.0 24.8 22.7 3.6 19.6 23.3 26.5 35.4 21.2 17.3 13.4 13.8 20.3 13.4 15.5 14.9 20.7 16.1 15.0 22.6 14.3 69.7 28.9 59.4 29.7 44.5 74.1 94.0 55.2 48.9 53.0 61.5 46.0 46.7 55.8 49.3 82.8 108.4 33.9 50.5 46.7 27.4 37.9 58.1 52.6 42.6 60.7 21.6 43.1 23.9 31.0 46.4 62.0 39.8 38.4 29.8 36.1 94.2 55.4 37.9 43.7 46.2 53.1 61.1 33.6 74.1 39.2 71.4 35.4 83.6 33.7 29.7 72.7 50.4 26.2 44.8 28.0 38.2 119.6 57.8 128.9 68.3 56.5 83.6 86.1 98.6 45.0 52.2 190.4 114.0 37.8 93.6 41.3 55.2 22.9 46.5 126.7 TMEM59 "C1orf8, HSPC001" ENSG00000116209 "Transmembrane protein 59" Q9BXS4 1 54026681-54053504 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075447 Approved NA NA 27000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA075447: " "unprognostic (2.63e-1)" "unprognostic (9.88e-2)" "unprognostic (2.63e-2)" "unprognostic (2.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (1.63e-2)" "unprognostic (8.28e-2)" "unprognostic (4.10e-1)" "unprognostic (6.57e-2)" "unprognostic (1.19e-1)" "unprognostic (4.49e-2)" "unprognostic (6.34e-3)" "unprognostic (9.84e-2)" "unprognostic (1.70e-1)" "unprognostic (6.83e-3)" "unprognostic (7.38e-2)" 257.6 359.7 181.9 164.6 220.8 259.7 341.4 240.3 253.8 343.6 379.5 488.3 364.1 208.7 415.5 241.8 403.2 299.3 275.7 178.4 202.0 473.7 505.7 264.0 162.6 240.6 205.0 225.4 586.1 532.5 170.2 325.8 239.1 350.2 485.3 254.2 550.3 279.9 194.5 194.7 369.1 219.8 235.7 188.7 433.0 174.9 204.6 186.9 341.3 247.6 189.2 289.2 202.6 286.8 188.9 122.3 142.8 185.2 844.1 371.1 182.8 347.9 499.1 211.5 276.0 99.1 391.9 96.7 322.6 595.6 257.7 281.1 166.2 237.5 221.9 237.7 177.4 133.5 266.6 166.1 317.8 165.7 268.7 408.3 411.2 207.5 219.2 566.9 246.6 127.8 158.9 326.3 245.1 91.6 97.9 137.3 201.0 528.3 226.3 94.0 251.6 403.2 257.6 248.0 208.2 173.3 381.5 386.0 398.3 266.2 184.9 348.4 259.3 259.8 90.7 193.3 187.8 289.0 338.7 114.5 349.4 275.4 222.3 1183.5 654.6 831.5 439.7 532.9 461.8 449.3 465.9 480.4 520.9 405.2 430.3 426.4 1196.5 430.4 595.9 527.1 576.1 1153.8 181.9 220.8 240.3 253.8 178.4 202.0 240.6 205.0 239.1 235.7 204.6 286.8 355.3 233.9 181.3 49.6 221.3 404.2 637.0 1214.2 237.3 150.2 409.0 325.1 155.1 479.0 991.8 437.7 118.9 477.7 244.5 905.2 160.4 527.8 357.1 348.5 201.9 279.5 408.2 277.0 44.3 352.5 528.7 410.6 226.8 217.2 155.2 89.5 334.4 413.2 320.2 132.9 42.1 672.8 1131.1 302.9 290.3 183.1 432.7 225.4 690.1 27.2 209.3 473.5 190.5 60.3 176.6 329.3 1064.8 354.0 692.8 583.2 1015.8 468.8 977.4 183.6 368.1 198.6 350.4 488.9 210.1 245.5 414.3 687.1 227.2 185.8 534.9 750.4 TMEM64 DKFZp762C1112 ENSG00000180694 "Transmembrane protein 64" Q6YI46 8 90621995-90791632 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "choroid plexus: 42.5;epididymis: 144.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 62.0;Hepatocytes: 51.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB034221 Uncertain NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB034221: AB_1567653" "unprognostic (3.61e-1)" "unprognostic (1.42e-1)" "unprognostic (1.58e-1)" "unprognostic (3.70e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (2.55e-3)" "unprognostic (4.84e-1)" "unprognostic (2.04e-1)" "unprognostic (1.26e-2)" "unprognostic (3.30e-1)" "unprognostic (2.35e-1)" "unprognostic (2.59e-2)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (6.17e-2)" "unprognostic (1.97e-1)" 17.1 12.0 5.2 9.3 9.3 3.4 8.4 7.1 7.1 15.4 42.5 10.5 9.6 10.9 144.9 10.5 8.8 10.4 7.2 4.9 6.8 13.6 20.8 9.5 12.9 9.4 7.4 16.3 15.3 6.8 4.7 10.3 7.8 11.4 5.5 1.0 17.8 17.3 8.9 6.4 9.8 16.3 7.5 8.9 7.1 12.2 7.4 5.1 22.9 7.1 12.1 10.6 7.8 14.5 26.5 20.3 10.0 5.4 45.7 33.0 5.5 19.2 18.2 14.8 16.3 5.7 17.8 17.2 7.5 11.8 6.4 9.0 26.9 13.0 19.5 34.8 9.8 32.1 7.3 12.8 16.1 1.9 5.1 43.4 14.0 6.1 13.8 17.1 15.1 4.1 14.8 36.9 25.1 35.3 0.1 4.6 1.5 13.6 10.6 3.8 22.1 8.7 29.2 50.6 7.1 20.0 12.6 10.9 23.5 13.3 10.9 1.5 15.1 14.9 13.1 10.8 15.8 24.3 0.4 18.8 13.4 3.9 20.0 2.7 0.1 0.1 1.5 0.3 1.9 3.1 1.6 1.7 0.3 2.0 0.7 1.1 0.0 3.2 0.4 0.2 0.8 0.9 5.2 9.3 7.1 7.1 4.9 6.8 9.4 7.4 7.8 7.5 7.4 14.5 16.7 9.6 12.5 5.2 15.7 24.1 12.7 5.4 62.0 0.7 7.3 11.4 20.4 7.2 3.7 22.0 0.0 25.3 18.6 2.5 1.9 3.9 3.7 3.3 9.6 9.0 7.8 18.7 9.9 10.2 6.2 18.1 6.1 4.6 14.0 13.5 6.1 51.7 4.0 1.7 14.1 4.5 8.2 9.7 11.6 3.2 46.9 11.1 24.9 9.4 1.9 4.0 4.1 8.0 46.8 8.8 2.4 21.4 12.6 19.7 16.7 30.6 3.7 0.0 0.0 10.5 11.9 3.4 2.2 17.4 23.4 15.7 13.3 23.7 7.2 8.6 TNFRSF1A "CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60" ENSG00000067182 "TNF receptor superfamily member 1A" P19438 12 6328757-6342114 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" Receptor "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 507.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004102, CAB010309" Approved "Secreted to blood" NA NA 17700 570000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB010309: AB_2206639, HPA004102: AB_1846232" "unprognostic (2.19e-2)" "unprognostic (3.76e-2)" "unprognostic (8.14e-2)" "prognostic favorable (8.22e-4)" "unprognostic (3.07e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.50e-1)" "unprognostic (1.41e-3)" "unprognostic (1.00e-1)" "unprognostic (8.05e-2)" "unprognostic (4.78e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (2.70e-7)" "unprognostic (1.43e-2)" "unprognostic (2.92e-2)" "unprognostic (5.14e-3)" "unprognostic (1.74e-1)" 166.5 133.3 33.7 76.7 34.4 42.4 120.0 35.3 38.6 105.0 47.8 114.1 101.5 111.8 23.0 105.6 106.7 88.8 80.6 32.4 40.3 94.5 176.5 130.7 38.1 45.7 40.4 90.6 57.3 53.7 57.3 82.4 39.6 86.9 56.4 3.5 76.0 46.3 91.0 103.7 109.5 97.5 40.4 111.3 84.4 22.6 39.7 39.2 97.4 63.1 36.1 113.2 113.2 37.4 40.2 296.4 40.9 60.2 277.7 282.0 75.7 82.2 143.0 108.2 93.9 34.7 153.6 3.7 28.9 179.3 85.6 107.1 12.9 96.4 74.1 0.8 25.3 20.3 79.2 82.2 245.5 104.4 66.9 291.8 94.4 90.2 131.4 250.4 134.1 42.0 33.7 29.8 126.3 57.1 34.0 100.0 102.1 146.1 87.6 27.9 66.6 32.4 83.7 70.7 0.1 2.1 117.8 60.9 62.5 103.6 16.4 111.4 146.0 84.6 71.7 64.7 78.4 0.1 10.6 12.8 100.5 95.9 107.0 17.1 165.8 93.5 62.2 130.4 60.0 0.5 25.1 51.0 123.7 0.4 22.3 34.0 507.2 9.7 111.5 31.6 26.2 117.3 33.7 34.4 35.3 38.6 32.4 40.3 45.7 40.4 39.6 40.4 39.7 37.4 102.0 51.3 37.1 15.3 4.8 123.0 115.8 127.3 81.4 0.4 50.1 35.9 9.3 67.2 70.8 27.6 0.0 62.0 35.5 204.0 15.6 98.7 1.2 25.5 66.5 111.8 33.6 30.1 4.6 119.4 120.2 109.3 43.8 42.3 7.6 27.6 159.2 145.0 176.4 0.0 1.3 56.8 32.6 146.7 113.4 5.4 102.2 102.4 71.2 32.8 127.1 15.9 104.0 11.1 0.9 116.6 239.4 65.8 4.2 141.2 227.5 96.9 30.8 0.7 124.9 64.1 89.4 1.3 1.1 57.0 134.7 148.6 31.2 21.5 57.4 140.1 TNNT3 "AMCD2B, DA2B, DKFZp779M2348, FSSV" ENSG00000130595 "Troponin T3, fast skeletal type" P45378 11 1919703-1938706 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 43 "skeletal muscle: 13906.8;tongue: 4507.7" "Cell type enriched" "Detected in many" 4 "Skeletal myocytes: 542.6" "Group enriched" "Detected in many" 9 "head and neck cancer: 28.8;urothelial cancer: 19.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 17 "basophil: 5.3" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.3" "Cell line enriched" "Detected in some" 21 "HSkMC: 24.0" "Region enhanced" "Detected in some" "olfactory bulb: 5.1" "Low region specificity" "Detected in single" "CAB002451, HPA037810, HPA056909" Enhanced NA NA 470000 "Cluster 34: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "CAB002451: AB_564151, HPA037810: AB_10966217, HPA056909: AB_2683273" "unprognostic (1.01e-2)" "prognostic favorable (7.37e-4)" "unprognostic (2.17e-2)" "unprognostic (2.30e-3)" "unprognostic (1.23e-2)" "unprognostic (1.29e-2)" "unprognostic (4.53e-3)" "unprognostic (1.20e-1)" "unprognostic (5.88e-2)" "unprognostic (4.29e-3)" "unprognostic (3.53e-2)" "unprognostic (4.34e-1)" "unprognostic (1.42e-5)" "unprognostic (2.99e-2)" "unprognostic (1.61e-1)" "unprognostic (1.79e-2)" "unprognostic (2.90e-2)" 31.2 2.4 0.2 1.4 0.4 1.5 20.0 0.1 0.4 16.3 0.1 5.8 0.2 6.6 2.8 62.5 14.4 1.9 185.3 0.2 0.1 0.8 1.4 3.7 1.4 0.1 0.1 1.7 2.2 0.3 2.5 41.3 0.1 20.7 0.5 0.0 216.0 3.1 13906.8 8.8 3.0 1.3 0.1 2.8 3.3 5.2 0.1 5.4 7.6 4507.7 2.0 20.3 12.0 0.2 0.0 0.0 0.0 0.0 0.5 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.4 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 33.1 0.0 1.9 0.0 0.8 2.9 3.9 5.9 2.2 0.0 0.4 0.3 17.8 0.0 10.1 0.0 0.0 24.5 1.5 0.0 0.0 0.1 0.3 2.4 0.3 33.9 0.0 0.0 0.1 0.0 6.7 42.0 0.0 0.1 0.0 3.0 0.0 0.0 2.7 0.0 0.0 0.0 6.1 0.0 2.3 2.5 110.9 2.2 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 94.8 0.3 0.2 0.0 0.0 42.5 0.0 0.0 542.6 11.2 0.1 0.6 2.9 3.4 18.3 2.0 0.7 0.0 17.1 TNS1 "DKFZp586K0617, MXRA6, PPP1R155, TNS" ENSG00000079308 "Tensin 1" Q9HBL0 2 217799588-218033982 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Cardiomyocytes: 339.0;Leydig cells: 169.6;Peritubular cells: 504.0;Sertoli cells: 368.1;Smooth muscle cells: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 135.1;ASC TERT1: 74.1;fHDF/TERT166: 66.6;REH: 75.4;TIME: 63.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018774, HPA036089, HPA036090" Approved Enhanced "Focal adhesion sites" NA NA 47000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" "CAB018774: AB_2207032, HPA036089: AB_10796111, HPA036090: AB_10794322" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.13e-2)" "unprognostic (5.46e-2)" "unprognostic (2.63e-2)" "unprognostic (1.20e-3)" "unprognostic (7.34e-2)" "unprognostic (2.55e-2)" "unprognostic (1.28e-3)" "unprognostic (5.57e-2)" "unprognostic (9.74e-2)" "unprognostic (4.71e-3)" "unprognostic (5.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.49e-2)" "prognostic unfavorable (5.19e-4)" 248.2 60.3 51.6 42.9 98.0 42.3 100.9 71.7 45.5 99.5 45.1 373.4 23.4 253.7 44.3 117.8 136.2 80.4 170.4 34.0 53.4 74.6 39.6 117.2 11.5 82.3 79.2 110.4 55.2 33.2 15.4 54.5 106.4 126.1 41.7 7.7 52.9 225.0 171.6 47.8 78.9 178.0 72.2 70.1 115.2 23.5 80.9 21.5 65.8 207.2 7.5 228.4 82.6 82.9 0.3 0.4 8.9 0.1 135.1 74.1 0.8 22.9 7.8 1.3 0.9 10.0 0.1 0.0 13.1 66.6 1.5 1.7 1.4 1.3 0.7 9.4 0.8 19.8 5.7 2.6 9.8 0.1 2.3 35.2 0.0 24.4 0.2 43.6 32.2 0.1 0.6 2.6 18.8 4.4 0.1 1.4 0.9 0.2 0.4 75.4 16.8 1.0 4.8 0.2 2.1 10.1 3.9 9.7 2.0 6.1 3.1 8.5 63.2 16.6 29.5 17.5 4.9 1.1 0.1 0.1 9.8 2.7 1.2 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.0 0.8 51.6 98.0 71.7 45.5 34.0 53.4 82.3 79.2 106.4 72.2 80.9 82.9 93.3 173.1 85.9 29.7 1.1 16.2 48.6 29.5 42.1 4.8 7.2 21.2 339.0 38.6 27.5 14.7 0.0 8.7 0.5 0.1 7.9 36.1 2.2 3.0 29.5 76.6 0.0 143.1 3.9 19.1 1.5 52.4 1.1 3.8 30.4 8.8 71.7 38.5 13.0 42.1 5.3 0.0 6.1 15.3 19.3 11.9 169.6 16.7 10.6 32.8 1.3 14.1 0.0 15.6 52.0 17.0 0.0 504.0 0.4 12.1 0.0 26.1 22.3 1.3 368.1 29.7 183.5 1.1 1.9 5.7 11.8 1.9 4.1 20.7 0.2 17.3 TNS2 "C1-TEN, KIAA1075, TENC1" ENSG00000111077 "Tensin 2" Q63HR2 12 53046969-53064379 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.3;Hepatic stellate cells: 93.1;Leydig cells: 141.7;Peritubular cells: 114.0;Sertoli cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 114.2;ASC TERT1: 78.1;HHSteC: 59.9;HSkMC: 86.2;hTERT-RPE1: 61.9;TIME: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034659 Approved NA Yes "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA034659: AB_10603349" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (5.21e-3)" "unprognostic (1.86e-1)" "unprognostic (3.59e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-2)" "unprognostic (8.97e-3)" "prognostic favorable (1.72e-4)" "prognostic favorable (9.32e-4)" "unprognostic (4.46e-2)" "unprognostic (1.09e-2)" "unprognostic (8.46e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" 156.3 66.9 59.3 14.8 66.2 0.3 121.6 46.4 57.8 121.2 33.3 79.0 14.4 98.8 14.0 28.3 121.0 32.5 99.6 43.7 49.2 67.3 66.5 83.4 15.8 58.0 63.5 104.1 34.6 17.0 43.3 33.1 54.0 66.3 11.5 6.0 35.7 41.1 69.0 42.1 56.7 28.5 50.8 79.5 58.2 15.9 58.3 7.2 80.6 58.8 6.4 82.6 81.1 57.9 2.0 21.2 2.7 2.2 114.2 78.1 0.7 11.8 27.1 6.2 3.2 1.4 5.7 0.1 25.3 32.1 2.6 1.5 0.1 7.8 2.4 0.5 0.8 0.4 25.5 11.3 59.9 0.3 0.5 86.2 0.3 7.9 4.7 61.9 36.3 0.4 0.6 0.3 24.9 5.1 0.2 0.4 1.9 1.4 5.8 0.7 6.6 0.3 8.2 0.4 1.2 2.7 4.4 2.4 8.8 1.6 26.1 0.7 52.1 12.9 14.8 4.7 2.0 0.6 0.3 0.1 20.4 0.3 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.3 66.2 46.4 57.8 43.7 49.2 58.0 63.5 54.0 50.8 58.3 57.9 109.3 3.2 25.7 33.3 0.5 0.0 6.8 0.0 5.2 21.1 15.1 13.0 7.9 10.0 2.5 5.5 0.0 0.5 0.9 0.4 3.9 5.8 2.8 4.4 41.1 69.6 1.2 2.7 3.1 4.4 0.4 40.5 2.0 14.5 0.0 7.7 93.1 37.5 2.4 30.3 7.8 3.9 0.0 4.4 0.0 7.2 141.7 2.9 0.0 31.9 0.1 29.6 0.0 46.3 35.6 2.4 9.0 114.0 1.8 4.5 2.1 2.6 1.5 11.3 151.2 51.3 64.7 4.2 4.4 1.3 0.0 0.8 1.4 2.6 1.8 2.1 TOB2 "APRO5, bK223H9, TOB4, TOBL, TROB2" ENSG00000183864 "Transducer of ERBB2, 2" Q14106 22 41433494-41446801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016603, HPA054112" Approved Approved Cytosol NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 54: Non-specific - Microtubule organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA016603: AB_2669400, HPA054112: AB_2682385" "unprognostic (1.21e-3)" "unprognostic (3.10e-2)" "unprognostic (3.41e-1)" "prognostic favorable (3.08e-5)" "unprognostic (3.89e-2)" "unprognostic (1.38e-1)" "unprognostic (1.36e-1)" "unprognostic (5.36e-2)" "unprognostic (4.94e-2)" "unprognostic (5.74e-2)" "unprognostic (3.18e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.18e-6)" "unprognostic (1.50e-2)" "unprognostic (7.14e-2)" "unprognostic (1.85e-1)" "unprognostic (7.13e-2)" 46.1 31.3 39.3 15.6 56.3 9.7 25.5 78.1 40.1 26.5 18.5 30.1 22.4 25.0 11.8 26.6 38.4 28.8 41.2 39.3 43.8 24.6 27.1 20.7 18.5 61.7 42.9 38.0 29.0 35.6 22.8 22.0 44.0 26.6 15.5 55.0 17.2 19.4 86.5 27.1 23.9 20.1 39.5 20.6 30.5 13.6 52.0 19.6 36.1 68.1 19.7 23.3 21.0 71.9 36.8 16.6 28.5 19.4 65.4 45.5 27.5 23.9 36.7 29.8 26.2 21.9 17.0 22.4 23.5 34.8 11.6 31.4 26.7 13.4 27.1 23.0 34.2 12.3 23.9 33.4 44.8 33.5 15.9 42.1 22.5 35.6 15.4 30.1 30.2 7.6 18.9 24.5 24.6 40.8 13.9 19.2 24.4 48.1 17.6 29.7 19.2 19.4 21.3 25.3 13.1 8.8 60.0 32.2 44.6 17.7 17.9 16.5 37.9 29.3 27.1 23.0 22.7 22.9 10.7 12.2 17.8 14.2 19.7 3.9 5.9 4.1 7.5 8.0 7.1 10.0 6.2 6.3 5.3 7.5 3.2 4.7 3.8 3.8 8.4 8.0 5.5 6.1 39.3 56.3 78.1 40.1 39.3 43.8 61.7 42.9 44.0 39.5 52.0 71.9 48.5 48.1 59.6 48.6 61.4 126.8 66.6 24.3 105.3 56.0 83.1 56.9 59.8 58.6 31.7 47.8 64.6 34.7 56.9 76.9 23.5 29.7 41.1 88.6 59.3 45.3 54.3 16.8 12.2 19.1 37.3 54.1 42.3 116.9 34.1 13.7 52.5 29.7 19.6 25.2 15.1 67.7 10.2 22.0 117.9 61.6 66.8 51.4 53.4 14.0 34.6 58.3 18.6 10.1 43.6 32.3 60.0 82.0 26.2 73.6 103.6 29.2 45.9 105.2 52.6 97.4 60.9 23.8 28.9 88.7 136.7 63.3 57.4 19.6 61.9 92.2 TOM1 ENSG00000100284 "Target of myb1 membrane trafficking protein" O60784 22 35299275-35347992 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 213.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 170.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000818, HPA001749" Approved Approved "Plasma membrane,Centriolar satellite,Cytosol" NA NA 44000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane, Centriolar satellite" "HPA000818: AB_2666101, HPA001749: AB_1080323" "unprognostic (3.75e-1)" "unprognostic (8.07e-2)" "unprognostic (5.18e-2)" "prognostic favorable (2.20e-5)" "unprognostic (1.11e-2)" "unprognostic (7.55e-2)" "unprognostic (4.07e-3)" "unprognostic (2.24e-1)" "unprognostic (9.92e-2)" "unprognostic (2.32e-1)" "unprognostic (3.71e-1)" "unprognostic (8.16e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.22e-1)" "unprognostic (1.30e-1)" "unprognostic (7.54e-3)" "unprognostic (3.31e-2)" 34.7 47.8 20.8 17.0 19.4 60.8 32.1 19.9 25.8 43.6 23.6 22.7 29.1 26.6 12.7 76.5 26.8 24.9 43.2 19.8 26.6 32.7 49.0 37.1 15.3 30.2 24.5 21.5 20.2 48.5 37.4 27.7 32.9 23.2 9.8 5.9 60.6 11.7 213.8 74.9 28.4 10.8 19.6 23.9 20.8 25.9 24.8 13.1 26.5 68.6 12.7 19.5 45.0 22.1 15.8 15.3 8.8 14.3 58.3 34.9 42.3 15.5 43.8 28.4 31.1 21.5 14.3 6.2 28.0 45.4 18.3 7.3 8.6 15.6 9.9 18.7 21.3 5.3 17.1 43.8 58.6 10.8 23.6 49.8 19.2 39.6 13.3 18.5 19.8 11.6 10.3 15.3 14.1 13.8 8.2 27.5 7.0 18.9 8.6 14.9 12.3 13.2 10.9 11.3 14.9 12.1 34.1 34.8 34.5 7.3 18.0 16.7 22.0 34.0 29.4 27.3 7.7 18.0 12.4 16.7 45.7 10.5 11.4 18.6 100.9 44.5 19.3 60.7 15.6 13.6 29.5 18.4 48.0 11.0 22.6 15.7 129.1 15.1 66.2 25.9 48.2 63.3 20.8 19.4 19.9 25.8 19.8 26.6 30.2 24.5 32.9 19.6 24.8 22.1 10.1 22.4 36.9 8.8 12.7 12.7 10.3 29.5 7.4 11.1 19.1 11.0 23.2 15.7 33.0 12.9 12.5 64.6 13.8 41.6 27.4 40.9 29.9 32.0 17.8 14.2 16.2 9.7 9.3 38.9 57.1 22.6 15.3 48.0 22.8 10.4 16.1 34.0 60.8 11.8 15.2 18.1 50.8 33.5 35.2 21.4 11.5 45.2 19.6 7.5 34.0 19.5 9.2 6.6 13.2 34.2 21.5 12.8 5.7 11.9 55.3 34.9 24.2 8.2 6.6 16.6 15.4 23.5 5.6 17.3 21.9 170.2 18.2 13.4 15.2 10.7 TRAM2 KIAA0057 ENSG00000065308 "Translocation associated membrane protein 2" Q15035 6 52497408-52577060 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 122.0;Plasma cells: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 250.1;ASC TERT1: 265.8;fHDF/TERT166: 253.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035092, HPA057925" Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA035092: AB_10610562, HPA057925: AB_2683557" "unprognostic (2.32e-2)" "unprognostic (2.19e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (1.12e-1)" "unprognostic (4.07e-2)" "unprognostic (8.90e-3)" "unprognostic (1.14e-1)" "unprognostic (1.65e-1)" "unprognostic (3.03e-1)" "unprognostic (3.01e-1)" "unprognostic (5.05e-1)" "prognostic unfavorable (1.41e-9)" "unprognostic (1.37e-2)" "unprognostic (1.60e-1)" "unprognostic (6.64e-2)" "unprognostic (1.19e-2)" 19.5 4.9 3.4 14.8 4.7 5.3 13.8 3.0 4.3 14.9 7.8 12.5 14.0 13.1 11.5 5.6 13.5 17.3 10.4 3.0 3.3 7.4 16.2 14.1 7.5 4.3 3.5 12.4 7.0 2.8 3.9 35.8 3.6 6.0 14.7 3.9 6.4 5.8 3.6 11.5 12.6 17.5 3.3 19.2 9.5 13.3 4.4 4.5 12.4 5.9 13.3 13.3 9.6 3.3 45.4 19.8 22.7 22.6 250.1 265.8 39.8 130.0 130.8 106.7 98.2 43.2 9.2 11.0 21.4 253.4 76.0 10.0 14.9 81.3 133.6 24.8 8.0 24.1 20.5 54.9 71.3 6.2 13.1 97.4 8.0 93.5 41.2 155.1 124.1 9.1 15.1 78.4 154.5 16.2 8.9 17.7 10.4 17.9 8.8 10.9 59.8 91.0 25.3 7.5 5.5 8.7 29.9 13.2 31.6 47.7 20.6 12.9 198.8 177.6 38.4 65.0 72.1 53.4 97.7 31.1 64.7 16.1 110.8 0.1 1.0 1.0 0.9 1.1 0.5 1.2 0.7 0.5 1.1 0.8 0.3 0.6 0.2 0.7 2.1 0.5 0.2 0.7 3.4 4.7 3.0 4.3 3.0 3.3 4.3 3.5 3.6 3.3 4.4 3.3 12.8 6.4 3.2 6.8 15.9 8.2 2.8 8.5 3.4 3.1 4.0 5.1 9.9 4.3 4.1 7.3 25.0 36.2 6.6 7.8 3.9 3.6 38.3 4.0 28.9 17.9 9.0 8.6 12.0 3.2 30.8 26.2 6.1 5.0 2.5 34.0 19.6 36.1 15.7 5.0 9.2 19.6 6.1 12.0 6.9 122.0 20.8 5.7 26.6 13.1 4.3 1.8 8.2 3.5 3.1 6.2 1.7 23.3 69.5 2.8 7.0 3.1 4.9 12.7 13.1 16.2 15.7 23.4 8.6 1.2 4.1 20.7 6.0 14.3 5.7 1.5 TRARG1 "BEC-1, DSPB1, IFITMD3, LOST1, TUSC5" ENSG00000184811 "Trafficking regulator of GLUT4 (SLC2A4) 1" Q8IXB3 17 1279662-1300978 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "adipose tissue: 101.4;breast: 68.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 294 "ASC diff: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050825 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050825: AB_2681252" "unprognostic (5.84e-2)" "unprognostic (7.21e-2)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (2.01e-1)" "unprognostic (2.91e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.83e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (1.90e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (5.10e-1)" 101.4 1.1 0.0 1.2 0.0 0.0 68.7 0.0 0.4 0.4 0.0 1.2 0.0 0.2 0.0 0.1 0.1 0.6 1.7 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 1.2 2.1 2.3 0.0 0.0 0.0 0.6 0.6 0.0 0.1 1.0 0.6 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIM35 "HLS5, KIAA1098, MAIR" ENSG00000104228 "Tripartite motif containing 35" Q9UPQ4 8 27284886-27311272 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 68.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019647 Approved Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA019647: AB_1858291" "unprognostic (7.67e-3)" "unprognostic (6.53e-2)" "unprognostic (1.61e-2)" "unprognostic (9.64e-3)" "unprognostic (9.35e-2)" "prognostic favorable (1.38e-4)" "unprognostic (8.79e-2)" "unprognostic (8.02e-2)" "unprognostic (5.72e-2)" "unprognostic (2.30e-1)" "unprognostic (1.12e-1)" "unprognostic (4.86e-2)" "prognostic favorable (5.59e-7)" "unprognostic (1.74e-2)" "unprognostic (1.69e-1)" "unprognostic (3.99e-2)" "unprognostic (1.92e-1)" 9.4 6.1 6.5 5.9 8.2 7.2 8.4 8.1 9.2 8.9 13.7 7.9 5.5 8.8 4.5 10.7 7.4 3.6 5.5 8.9 6.8 6.3 11.9 5.9 6.9 10.0 7.7 6.1 5.9 4.6 4.2 5.3 9.7 7.3 3.9 4.1 16.3 9.0 5.0 32.2 6.2 7.2 6.7 6.2 5.9 6.4 9.8 8.1 4.6 4.6 7.0 8.2 10.4 11.7 17.4 12.3 7.0 9.0 68.4 16.9 16.1 10.3 8.1 9.4 10.0 17.6 3.4 15.3 10.3 11.5 8.3 17.0 10.1 19.9 7.1 8.7 7.6 15.1 10.3 15.1 17.8 8.3 12.4 24.6 44.2 13.3 26.1 5.0 9.4 14.5 10.8 16.4 7.7 9.0 27.8 11.3 12.3 11.1 9.8 13.8 9.0 13.3 6.4 13.5 11.9 11.4 8.6 8.1 14.3 6.7 5.2 13.2 10.9 8.5 17.7 27.1 10.2 7.5 8.5 11.1 12.1 12.0 8.5 11.9 3.0 4.0 8.6 3.0 9.7 5.3 11.2 9.7 3.8 3.8 7.5 11.2 1.1 8.9 3.4 6.4 14.5 5.3 6.5 8.2 8.1 9.2 8.9 6.8 10.0 7.7 9.7 6.7 9.8 11.7 9.4 3.2 4.5 5.2 4.4 20.9 6.0 4.6 40.9 3.5 3.6 2.7 5.0 8.6 3.8 12.9 6.2 3.5 3.2 3.6 0.0 3.7 1.0 4.0 3.7 6.7 2.4 8.6 8.3 5.1 2.8 6.6 6.1 4.6 5.7 3.8 23.9 20.3 2.9 5.0 5.3 2.7 6.1 8.9 6.2 0.6 12.8 6.9 7.2 3.7 5.2 3.5 3.1 4.5 16.8 4.7 2.0 10.9 4.8 3.6 4.5 6.1 0.9 3.5 0.0 3.4 5.5 1.3 3.9 15.0 22.3 1.5 6.9 2.4 3.5 2.5 TSKU "E2IG4, LRRC54, TSK" ENSG00000182704 "Tsukushi, small leucine rich proteoglycan" Q8WUA8 11 76782251-76798153 "Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 237.3" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 506.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 168.0;ASC diff: 282.5;OE19: 188.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008164 Approved Approved "Nucleoplasm,Nuclear bodies" "Secreted to blood" NA NA 6200000 "Cluster 6: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "Nuclear bodies" "HPA008164: AB_1853327" "unprognostic (1.07e-2)" "unprognostic (2.29e-3)" "unprognostic (6.15e-2)" "prognostic favorable (3.66e-4)" "unprognostic (7.05e-2)" "unprognostic (2.39e-1)" "unprognostic (3.08e-1)" "unprognostic (2.17e-3)" "unprognostic (4.81e-2)" "unprognostic (4.62e-2)" "prognostic unfavorable (2.87e-4)" "prognostic favorable (1.66e-4)" "prognostic unfavorable (2.80e-8)" "unprognostic (1.47e-1)" "unprognostic (4.93e-2)" "unprognostic (6.71e-2)" "unprognostic (3.88e-2)" 96.5 12.1 4.2 8.3 4.5 2.1 80.4 6.5 5.8 147.1 27.8 23.5 37.1 46.4 20.6 62.8 67.7 14.9 34.8 6.5 2.7 41.5 237.3 15.0 2.4 4.4 3.1 47.0 16.8 6.4 14.8 30.3 5.0 44.0 14.4 4.1 33.9 24.6 9.5 60.0 32.3 41.1 1.9 6.9 28.2 9.1 3.9 4.7 37.6 5.7 5.6 41.6 99.6 4.4 3.7 168.0 19.1 18.4 282.5 36.1 34.6 5.9 32.2 12.6 12.0 22.2 48.0 0.3 32.7 21.1 53.7 68.6 10.9 42.7 3.9 35.7 5.9 8.3 43.5 63.1 53.6 3.0 11.9 37.3 46.0 22.5 18.2 24.0 15.7 6.4 19.9 1.4 11.7 81.9 0.5 6.5 24.5 188.9 7.4 5.9 18.3 28.7 29.7 29.7 16.8 28.5 32.7 25.7 15.4 15.8 34.5 2.7 4.9 35.4 28.2 86.8 14.2 1.1 0.6 1.4 16.6 8.9 6.4 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.0 4.2 4.5 6.5 5.8 6.5 2.7 4.4 3.1 5.0 1.9 3.9 4.4 6.2 0.0 0.5 1.0 0.5 17.3 12.1 25.8 27.9 3.5 13.6 13.2 3.2 11.5 12.1 1.8 0.0 50.0 0.1 33.2 0.0 6.7 0.2 8.1 35.6 5.8 7.8 13.5 0.5 21.7 71.8 33.0 14.8 10.6 1.3 38.7 9.7 506.3 9.9 0.0 0.1 12.4 26.4 9.1 6.4 2.0 37.3 0.8 5.4 1.9 1.6 9.2 0.0 0.0 0.0 21.3 21.2 45.1 0.1 14.6 28.6 21.9 3.0 0.6 0.0 1.0 11.3 0.4 2.0 22.3 22.6 43.8 1.6 8.6 13.8 20.1 TTC3 "DCRR1, RNF105, TPRD, TPRDI, TPRDII, TPRDIII" ENSG00000182670 "Tetratricopeptide repeat domain 3" P53804 21 37073226-37203112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016810, HPA023964, HPA036304" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli" Cytosol "HPA016810: AB_1858434, HPA023964: AB_1858435, HPA036304: AB_2675049" "unprognostic (3.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (1.53e-1)" "unprognostic (1.37e-2)" "unprognostic (8.52e-2)" "unprognostic (9.29e-2)" "unprognostic (8.71e-2)" "unprognostic (1.61e-1)" "unprognostic (2.05e-2)" "unprognostic (1.99e-1)" "unprognostic (9.10e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (6.74e-2)" 45.8 29.3 28.1 27.1 25.0 26.4 43.1 36.3 35.3 59.3 45.7 34.6 24.7 38.9 58.6 27.9 34.9 35.4 28.0 38.9 15.5 37.7 31.7 24.4 29.4 10.0 11.1 60.6 42.9 39.1 35.6 29.0 11.8 51.2 36.3 63.0 50.0 41.4 27.7 30.7 30.3 34.6 6.7 27.3 40.9 27.4 15.3 38.0 64.8 30.6 29.2 30.6 9.4 21.4 72.9 25.4 115.3 22.2 108.9 156.8 40.0 77.5 96.0 34.2 46.1 34.0 35.8 62.3 26.6 130.9 32.1 23.3 35.3 47.9 48.2 66.3 25.0 125.6 38.0 44.1 39.6 70.9 39.1 81.9 28.8 35.0 31.0 68.8 51.6 54.1 77.3 71.1 65.2 56.0 69.4 18.8 33.3 48.0 42.6 91.6 55.3 33.2 39.4 55.3 87.7 67.6 97.2 55.2 49.1 26.5 62.2 27.3 68.3 49.2 19.5 61.2 30.4 71.1 55.1 60.6 80.7 69.9 37.9 4.8 6.2 6.8 11.5 6.4 17.1 13.0 13.3 15.8 10.8 15.1 23.2 14.4 1.0 12.8 8.6 17.3 10.0 4.8 28.1 25.0 36.3 35.3 38.9 15.5 10.0 11.1 11.8 6.7 15.3 21.4 78.3 125.0 142.7 161.3 144.8 65.9 94.8 102.7 86.0 347.7 175.8 140.1 134.7 68.6 118.2 75.4 227.2 50.1 129.5 67.8 166.3 91.1 192.7 115.0 217.4 78.9 190.2 65.4 424.5 75.3 93.5 171.0 131.5 132.0 64.6 256.8 99.6 94.4 61.4 329.7 396.0 163.1 99.7 95.2 83.7 192.4 210.0 86.8 211.7 111.5 87.4 196.5 93.7 321.7 261.9 73.3 96.5 261.1 167.6 121.4 72.8 96.1 108.6 233.9 52.6 245.8 127.9 400.0 258.4 91.7 62.8 52.7 109.7 204.1 148.1 103.9 TTPAL "C20orf121, dJ179M20.3" ENSG00000124120 "Alpha tocopherol transfer protein like" Q9BTX7 20 44475874-44494603 "Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 28.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 91.0;HSkMC: 78.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046957, HPA066532" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus, Cytosol" "HPA046957: AB_10959741, HPA066532: AB_2685686" "unprognostic (8.71e-2)" "unprognostic (3.05e-2)" "unprognostic (2.90e-1)" "prognostic unfavorable (3.47e-5)" "unprognostic (1.69e-1)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.54e-1)" "unprognostic (1.64e-2)" "unprognostic (2.32e-1)" "unprognostic (5.06e-2)" "unprognostic (4.50e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (8.09e-5)" "unprognostic (2.09e-2)" "unprognostic (2.88e-1)" "unprognostic (2.24e-2)" "unprognostic (7.93e-2)" 8.2 4.4 5.4 5.7 5.5 9.0 5.2 4.7 5.4 6.1 7.1 3.6 3.5 5.0 4.7 5.5 4.9 4.0 2.8 6.3 7.3 4.1 28.7 3.3 8.4 5.2 6.3 4.1 6.4 7.2 7.0 2.8 8.1 4.6 4.0 2.9 5.0 4.3 2.7 12.5 4.0 5.4 3.2 4.6 4.0 3.0 5.2 6.2 7.6 1.7 7.9 5.0 5.3 4.3 21.1 10.8 8.2 14.6 91.0 35.3 8.2 22.4 31.1 21.3 18.1 40.1 12.5 13.1 18.8 20.9 38.8 20.4 10.5 35.2 22.9 13.6 4.8 6.2 11.6 11.8 25.2 9.3 14.1 78.5 22.6 20.9 35.0 10.1 7.3 11.0 8.0 13.4 17.2 24.2 9.1 5.9 9.8 11.4 18.0 2.8 8.8 7.1 8.3 15.0 18.2 8.6 31.1 13.5 14.0 10.1 14.8 6.0 7.5 47.2 18.8 14.2 19.5 19.8 14.5 14.0 22.8 6.6 14.1 0.6 1.1 1.8 4.0 2.2 4.4 3.6 3.6 4.2 1.1 3.8 3.0 4.7 2.6 5.7 2.3 2.0 3.8 2.3 5.4 5.5 4.7 5.4 6.3 7.3 5.2 6.3 8.1 3.2 5.2 4.3 3.9 9.6 11.4 6.2 15.7 6.4 17.2 9.5 1.8 24.4 8.0 5.8 5.3 18.6 10.3 22.0 25.0 7.4 19.8 8.7 1.9 10.2 4.9 8.4 30.5 7.5 9.5 38.9 8.3 9.4 8.6 13.8 2.6 9.3 9.5 8.3 8.2 60.7 4.9 18.5 9.1 5.3 2.0 17.6 6.5 10.3 18.6 6.9 3.6 2.8 8.4 11.5 30.9 8.5 7.1 13.3 9.3 11.3 8.6 14.3 11.0 4.7 8.4 20.3 6.6 16.3 10.1 9.6 11.4 6.1 20.0 10.9 17.9 12.3 9.5 10.9 TXNIP "ARRDC6, EST01027, HHCPA78, THIF, VDUP1" ENSG00000265972 "Thioredoxin interacting protein" Q9H3M7 1 145992435-145996579 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 2550.5;NK-cells: 2028.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 951.8;HSkMC: 1276.5;hTCEpi: 664.0;hTERT-RPE1: 781.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031085, HPA053694" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Cytosol "HPA031085: AB_10601706, HPA053694: AB_2682232" "unprognostic (1.45e-1)" "unprognostic (1.57e-2)" "unprognostic (1.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.92e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (2.51e-1)" "unprognostic (9.23e-2)" "unprognostic (1.20e-1)" "unprognostic (3.65e-2)" "unprognostic (1.19e-1)" "unprognostic (8.49e-3)" "unprognostic (1.35e-2)" "unprognostic (1.31e-1)" "unprognostic (8.19e-2)" "unprognostic (2.22e-3)" 1542.7 466.8 130.3 566.5 159.9 404.7 1396.7 137.1 158.5 846.0 133.8 965.4 223.3 811.8 381.2 428.7 730.3 395.0 745.2 120.3 136.6 532.6 204.0 841.9 800.8 182.0 144.9 382.9 580.5 634.0 192.3 594.0 185.4 352.4 487.5 14.5 567.0 554.5 1446.1 1060.4 810.7 658.7 157.1 946.4 713.4 106.4 159.2 373.7 556.6 2306.2 1068.8 740.9 638.7 217.3 56.5 0.2 13.0 0.9 291.6 951.8 29.7 66.0 131.3 58.5 79.7 35.3 74.6 15.8 379.6 18.1 9.7 15.0 13.0 124.8 154.8 74.2 7.1 45.7 20.2 32.6 13.8 189.7 91.7 1276.5 664.0 119.0 206.7 781.9 23.2 61.8 184.8 121.2 30.2 76.5 31.9 180.2 36.3 112.5 48.5 28.5 107.8 498.3 151.6 122.8 61.7 99.9 283.1 80.5 239.0 26.2 29.1 266.6 56.5 160.1 10.0 304.2 108.7 169.3 170.7 13.8 39.3 86.6 86.3 1059.6 571.2 1219.2 792.2 551.3 729.8 519.3 668.8 710.4 334.4 542.4 650.2 708.5 1246.6 637.1 496.3 154.8 674.5 1684.4 130.3 159.9 137.1 158.5 120.3 136.6 182.0 144.9 185.4 157.1 159.2 217.3 2550.5 227.6 328.5 26.4 1360.4 70.7 236.9 129.8 413.8 6.5 167.4 111.2 526.0 185.8 184.4 272.2 29.2 5.0 1004.6 578.0 450.0 79.7 8.3 179.8 594.5 740.2 164.2 270.8 0.2 53.8 4.1 666.5 160.5 464.2 377.4 53.6 349.8 114.8 231.9 6.7 0.5 320.9 136.3 845.1 184.9 35.5 654.5 730.8 108.5 36.5 892.0 3.6 2028.9 45.2 55.8 225.7 459.4 447.2 639.6 370.7 79.0 169.3 155.8 3.7 1196.5 452.4 398.7 7.6 63.7 160.1 72.2 10.9 1142.8 303.9 186.9 516.2 UBQLN2 "Chap1, CHAP1/DSK2, Dsk2, LIC-2, N4BP4, PLIC-2, PLIC2, RIHFB2157" ENSG00000188021 "Ubiquilin 2" Q9UHD9 X 56563627-56567868 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Autophagy "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006431, CAB013481" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "CAB013481: AB_2533341, HPA006431: AB_1078707" "unprognostic (1.23e-2)" "unprognostic (2.88e-1)" "unprognostic (1.47e-1)" "unprognostic (1.51e-3)" "unprognostic (1.76e-2)" "unprognostic (5.08e-2)" "prognostic unfavorable (2.29e-4)" "unprognostic (2.66e-1)" "unprognostic (1.25e-1)" "unprognostic (4.42e-1)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (8.81e-2)" "unprognostic (1.35e-1)" "unprognostic (1.45e-1)" "unprognostic (8.88e-2)" "unprognostic (8.42e-3)" 13.8 20.2 24.9 14.9 26.8 11.1 12.1 19.7 30.6 15.9 12.7 15.7 11.2 16.6 15.9 18.7 17.5 14.5 21.6 27.4 25.5 13.5 19.4 13.8 18.4 20.2 20.4 25.7 10.5 23.6 16.3 15.8 22.1 20.2 12.1 22.2 14.4 20.0 28.0 13.6 12.4 18.4 21.3 14.9 13.1 4.4 22.6 18.9 20.7 22.8 18.6 18.6 11.1 25.5 36.3 26.5 25.9 30.6 58.3 37.0 16.3 28.6 33.9 21.0 23.2 14.9 16.6 27.6 30.5 34.0 32.9 20.7 50.0 31.9 25.3 43.0 30.1 11.2 34.2 15.9 30.6 22.1 23.7 34.7 39.6 28.3 24.6 30.3 18.7 17.6 13.3 29.5 33.6 16.9 28.5 19.2 21.7 11.6 31.1 25.3 33.7 26.3 42.8 27.9 31.9 29.9 41.3 18.1 17.4 45.2 30.4 16.1 21.2 22.2 22.5 32.4 17.5 11.1 14.8 18.9 24.9 23.1 19.3 50.0 23.6 24.1 15.1 31.1 17.1 7.8 22.9 17.7 17.8 8.6 30.3 18.9 20.4 20.9 34.2 6.5 23.5 20.3 24.9 26.8 19.7 30.6 27.4 25.5 20.2 20.4 22.1 21.3 22.6 25.5 13.9 22.4 17.2 0.0 30.5 31.2 41.6 27.4 20.5 42.3 14.5 11.3 37.6 15.7 25.0 18.4 18.8 28.8 15.4 12.1 17.6 20.0 0.1 11.8 22.7 18.9 34.2 18.3 0.0 16.6 26.7 27.9 13.7 15.7 12.7 14.2 18.2 20.3 24.7 42.1 0.0 20.3 18.3 30.7 25.3 1.6 24.8 21.1 17.8 0.0 35.9 22.3 42.2 0.0 0.0 18.9 12.7 36.5 23.5 32.0 20.7 16.4 27.5 35.8 13.1 25.4 29.8 0.3 1.5 32.7 30.4 40.0 28.7 12.2 19.3 35.6 USP35 KIAA1372 ENSG00000118369 "Ubiquitin specific peptidase 35" Q9P2H5 11 78188812-78215232 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Early spermatids: 39.1;Granulosa cells: 30.8;Late spermatids: 121.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055213, HPA058592" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" Nucleoplasm "HPA055213: AB_2682740, HPA058592: AB_2683766" "unprognostic (6.69e-2)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (6.87e-3)" "unprognostic (3.38e-2)" "unprognostic (1.08e-2)" "unprognostic (2.00e-1)" "unprognostic (1.46e-1)" "unprognostic (3.57e-2)" "unprognostic (3.84e-3)" "unprognostic (1.03e-2)" "unprognostic (3.11e-2)" "unprognostic (1.29e-3)" "unprognostic (2.93e-1)" "unprognostic (1.31e-1)" "unprognostic (4.38e-2)" "unprognostic (1.49e-2)" 6.1 19.8 8.0 3.6 7.4 2.5 5.1 5.1 8.0 9.2 7.4 7.6 3.5 6.7 3.2 6.0 6.4 3.5 10.2 8.3 7.1 6.2 16.8 7.0 3.3 9.0 8.2 7.4 5.9 12.4 13.4 4.7 9.4 5.9 1.9 2.1 3.9 3.2 4.1 3.0 4.5 4.7 3.9 4.9 4.6 4.5 8.3 6.2 8.7 4.0 2.6 6.6 7.7 6.4 2.2 3.3 5.7 6.1 9.7 8.7 3.9 5.0 5.8 5.8 4.0 8.4 4.7 1.7 5.0 9.5 6.2 5.8 3.8 7.8 3.4 12.8 2.0 2.9 9.8 5.0 7.4 1.8 8.3 7.4 5.1 12.1 3.5 11.4 7.2 6.5 4.1 4.2 4.6 2.0 4.7 7.6 1.7 6.2 5.3 2.9 5.2 2.0 4.5 4.1 2.8 5.9 3.9 5.1 1.9 8.1 4.3 1.6 8.9 10.6 5.9 12.8 2.7 5.7 2.0 2.7 3.1 2.0 6.3 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 7.4 5.1 8.0 8.3 7.1 9.0 8.2 9.4 3.9 8.3 6.4 1.3 0.0 1.8 5.9 1.2 0.8 0.2 0.7 3.4 0.8 1.0 0.6 3.5 0.0 0.3 0.0 6.2 0.7 1.0 1.2 0.0 1.1 39.1 1.3 2.7 1.9 0.0 0.4 5.2 2.0 1.6 2.0 5.1 1.2 0.0 30.8 1.4 2.7 1.6 0.0 4.8 0.9 0.0 0.6 0.8 121.6 1.5 1.4 1.8 2.8 2.7 0.4 0.0 3.5 2.8 2.0 0.1 3.0 0.8 0.3 0.8 1.0 0.5 0.6 6.6 0.7 1.3 1.2 2.4 4.1 1.0 0.3 2.9 2.1 1.3 0.2 VCAM1 CD106 ENSG00000162692 "Vascular cell adhesion molecule 1" P19320 1 100719742-100739045 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "lymphoid tissue: 389.3" "Cell type enhanced" "Detected in many" "Ductal cells: 142.6;Hepatic stellate cells: 94.9;Kupffer cells: 561.9;Proximal tubular cells: 188.4;Theca cells: 186.8" "Cancer enriched" "Detected in all" 8 "renal cancer: 89.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HHSteC: 164.7;HSkMC: 111.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000154, HPA034796, HPA069867" Enhanced Approved "Cell Junctions" NA NA 624000000 1300000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Cell Junctions" "CAB000154: , HPA034796: AB_2674333, HPA069867: AB_2686215" "unprognostic (2.96e-1)" "prognostic favorable (3.82e-4)" "unprognostic (1.31e-1)" "unprognostic (7.49e-3)" "unprognostic (1.04e-1)" "prognostic favorable (7.19e-5)" "unprognostic (1.60e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (1.20e-1)" "unprognostic (3.95e-2)" "unprognostic (8.23e-2)" "unprognostic (1.80e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.55e-2)" 29.1 43.2 4.0 34.7 3.5 8.3 15.0 5.0 4.5 6.7 6.0 15.0 15.4 9.4 2.4 7.7 9.8 29.5 9.4 2.8 7.6 64.3 43.7 18.1 96.3 6.5 6.2 39.5 13.3 18.4 7.0 43.2 7.0 9.7 23.5 1.5 8.7 5.5 3.1 3.6 14.4 11.0 6.0 389.3 14.4 5.4 11.2 24.6 7.3 6.3 75.9 72.7 5.5 5.9 0.0 0.0 0.8 0.3 0.6 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.0 0.1 25.7 0.0 0.0 0.0 0.0 164.7 0.2 0.0 111.0 0.0 29.3 0.2 0.0 1.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 3.5 5.0 4.5 2.8 7.6 6.5 6.2 7.0 6.0 11.2 5.9 9.6 0.0 5.6 0.0 1.7 9.9 0.5 0.4 0.0 0.1 0.9 0.6 1.9 0.0 0.2 3.7 0.0 1.3 1.1 0.0 9.8 142.6 0.3 0.7 14.0 40.3 0.0 2.7 0.0 3.2 1.2 60.1 0.0 0.8 1.3 7.5 94.9 3.2 3.6 0.0 0.0 0.0 0.0 561.9 15.9 0.0 17.1 7.9 1.8 6.5 0.0 4.0 0.0 0.0 0.1 2.3 1.1 7.5 0.9 1.3 0.0 188.4 1.5 0.0 0.0 5.5 19.2 0.1 2.3 0.4 7.4 2.7 10.0 186.8 0.1 0.4 VEGFD "FIGF, VEGF-D" ENSG00000165197 "Vascular endothelial growth factor D" O43915 X 15345596-15384413 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 42.7" "Cell type enriched" "Detected in some" 12 "Fibroblasts: 39.8" "Cancer enhanced" "Detected in some" "liver cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.4;ASC TERT1: 2.8;EFO-21: 1.3;HSkMC: 2.8" "Group enriched" "Detected in many" 4 "amygdala: 2.1;cerebral cortex: 3.5;hippocampal formation: 3.3;white matter: 2.6" "Not detected" "Not detected" HPA027342 Uncertain "Secreted to blood" NA NA 592000 450000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA027342: AB_1848597" "unprognostic (5.90e-2)" "unprognostic (9.79e-3)" "unprognostic (1.02e-1)" "unprognostic (1.06e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-1)" "unprognostic (6.06e-3)" "unprognostic (5.57e-2)" "unprognostic (2.24e-3)" "unprognostic (2.65e-2)" "unprognostic (1.59e-5)" "unprognostic (3.08e-2)" "unprognostic (2.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.70e-1)" "unprognostic (3.85e-1)" "unprognostic (1.75e-2)" 11.4 9.9 1.8 0.7 1.8 0.0 20.3 1.5 2.3 19.2 1.5 5.0 1.2 3.8 4.9 2.7 4.1 2.8 15.5 1.6 2.0 1.7 1.5 42.7 0.4 1.8 1.7 4.4 0.7 2.7 7.0 0.2 2.0 1.5 2.0 0.3 2.3 1.8 17.6 1.2 4.2 3.3 1.3 2.8 5.8 0.6 2.1 0.3 1.5 23.0 1.3 6.0 8.1 2.0 0.0 0.6 0.5 0.9 3.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.3 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.1 0.0 0.3 2.8 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.3 0.6 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 1.5 2.3 1.6 2.0 1.8 1.7 2.0 1.3 2.1 2.0 3.1 3.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.5 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 39.8 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.3 1.6 0.0 0.0 VIM ENSG00000026025 Vimentin P08670 10 17228241-17237593 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 4879.0;Langerhans cells: 4893.1;Leydig cells: 5013.2;Muller glia cells: 8977.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 18287.8;fHDF/TERT166: 10084.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000080, HPA001762, CAB058687" Enhanced Supported "Intermediate filaments" NA NA 35000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Intermediate filaments" "CAB000080: AB_2304493, CAB058687: AB_2665570, HPA001762: AB_1080568" "unprognostic (1.02e-1)" "unprognostic (2.58e-1)" "unprognostic (2.87e-2)" "prognostic favorable (9.75e-6)" "unprognostic (3.81e-2)" "unprognostic (2.52e-1)" "unprognostic (3.21e-1)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" "unprognostic (2.05e-1)" "unprognostic (9.29e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.87e-3)" "unprognostic (7.32e-2)" "unprognostic (1.82e-1)" "unprognostic (9.47e-3)" 3467.6 423.1 349.3 610.6 369.5 1455.5 2362.8 289.1 527.4 1816.3 568.1 923.2 218.4 1226.5 400.0 451.5 1458.7 960.2 1364.3 337.5 404.6 473.6 192.8 1133.2 806.2 667.4 328.2 3690.8 370.0 224.8 574.5 1030.0 443.7 570.0 400.8 731.0 628.5 551.8 363.7 1126.8 674.7 1109.3 414.6 819.9 522.8 251.7 472.7 412.2 1391.1 555.8 744.7 983.5 1366.6 425.5 21.2 1119.0 1981.0 3180.7 6407.4 18287.8 3.0 5238.5 3458.9 3859.2 3421.5 8.5 70.4 2.9 273.2 10084.4 1804.7 8.4 283.8 147.0 3734.1 3567.5 387.2 563.2 523.5 0.3 1967.3 301.1 222.8 6746.8 6.5 5712.0 3213.4 9020.8 6366.3 372.4 889.3 1575.4 6939.5 4.5 736.6 911.2 632.4 1.4 1394.0 564.8 2745.9 95.7 3925.3 0.8 8.1 946.6 1.4 6.9 5447.5 1133.1 8.6 341.8 5459.0 3819.8 1644.5 3244.7 6311.5 1754.4 953.7 130.4 5775.4 28.9 3726.3 667.8 751.8 215.2 219.5 469.3 278.7 176.3 357.0 285.0 866.0 117.5 217.1 217.2 409.3 99.2 471.2 342.3 481.5 615.4 349.3 369.5 289.1 527.4 337.5 404.6 667.4 328.2 443.7 414.6 472.7 425.5 3211.7 157.0 349.4 53.5 605.8 725.8 21.6 361.2 58.1 74.2 108.8 539.1 109.5 94.4 157.3 108.5 50.1 22.1 1110.1 9.1 5.9 198.8 58.1 922.9 2314.1 2923.2 309.1 236.5 0.4 569.0 45.8 3443.0 101.4 693.7 2776.4 4879.0 2195.6 19.2 3541.4 33.7 0.3 1.8 16.2 2841.2 4893.1 131.6 5013.2 3177.8 3082.5 85.3 3893.1 8977.0 259.5 1.0 0.4 525.9 1.5 2336.6 2097.2 79.5 3.1 181.6 90.7 284.1 1420.0 3171.9 3714.2 55.1 27.5 39.4 473.0 52.7 1566.3 1791.1 6.2 28.9 VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 454.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 749.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 638.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" 99.4 107.6 56.0 38.4 60.4 55.2 87.0 60.3 73.5 111.0 64.9 97.0 44.2 109.9 87.2 51.8 90.8 58.9 99.1 57.4 59.3 122.7 454.9 77.4 35.8 64.4 59.5 115.1 168.0 51.3 115.7 45.6 63.8 76.3 41.1 23.0 92.4 69.8 34.4 81.1 82.3 84.7 59.9 62.2 88.1 55.6 68.5 35.0 76.3 32.2 32.6 100.6 88.0 64.8 73.6 187.7 57.2 165.4 638.0 389.6 68.2 269.0 229.3 128.9 218.5 79.0 83.3 54.9 141.6 331.6 87.2 66.2 79.4 103.5 139.5 81.9 204.8 52.5 239.9 378.2 103.1 104.1 74.1 225.0 54.2 173.4 146.6 336.8 141.0 78.2 70.3 130.6 253.6 271.1 74.4 205.9 106.8 98.0 175.9 132.7 160.3 286.8 127.7 61.8 119.5 146.9 118.7 84.2 137.8 91.2 138.3 123.9 126.8 171.1 61.5 159.6 101.9 76.1 80.2 50.7 445.8 174.5 90.8 77.0 127.5 196.2 118.1 94.7 116.8 91.7 116.7 119.4 127.6 102.6 102.9 101.4 104.0 84.2 98.2 157.4 143.1 112.8 56.0 60.4 60.3 73.5 57.4 59.3 64.4 59.5 63.8 59.9 68.5 64.8 95.1 57.7 51.0 5.9 30.6 84.6 68.0 157.0 10.8 12.3 93.3 117.3 20.9 141.5 64.3 108.5 8.4 85.7 48.1 34.3 62.6 204.2 6.1 25.8 83.7 89.5 67.1 32.4 8.8 129.4 293.6 132.8 10.7 48.8 55.3 60.3 118.9 749.9 184.1 10.1 7.5 44.2 46.8 80.1 94.3 13.9 158.1 66.9 115.6 5.6 107.4 68.8 51.5 6.6 17.6 103.8 28.2 172.3 29.5 59.5 152.9 204.6 33.4 19.3 59.2 78.4 99.8 30.6 34.2 10.7 112.0 39.5 39.7 82.4 49.0 55.2 VPS35L "C16orf62, MGC16824" ENSG00000103544 "VPS35 endosomal protein sorting factor like" Q7Z3J2 16 19555240-19706793 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 32.4;Cytotrophoblasts: 29.4;Distal tubular cells: 29.4;Hofbauer cells: 44.9;Syncytiotrophoblasts: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042969, HPA053547" Uncertain Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042969: AB_10794920, HPA053547: AB_2682183" "unprognostic (7.15e-2)" "unprognostic (6.54e-2)" "unprognostic (1.17e-1)" "unprognostic (7.20e-2)" "unprognostic (1.51e-1)" "unprognostic (2.67e-1)" "unprognostic (1.15e-1)" "unprognostic (2.74e-1)" "unprognostic (2.52e-1)" "unprognostic (1.22e-3)" "unprognostic (3.57e-2)" "unprognostic (2.06e-1)" "prognostic favorable (1.31e-8)" "unprognostic (1.82e-3)" "unprognostic (8.92e-2)" "unprognostic (5.08e-2)" "unprognostic (1.13e-2)" 19.3 22.7 23.3 15.9 33.5 13.2 17.1 21.8 24.9 21.2 11.7 19.2 13.7 20.1 22.4 16.8 19.2 17.5 17.8 20.7 23.5 22.2 14.4 16.2 14.6 23.3 24.4 23.3 16.5 35.6 20.4 20.2 24.6 15.9 19.4 16.1 12.4 18.9 22.2 13.8 15.3 25.1 20.5 17.2 13.3 31.5 28.0 16.1 22.7 25.2 16.6 18.3 15.6 40.3 22.3 37.5 35.7 28.4 44.2 60.1 5.8 32.5 52.3 33.9 38.9 6.4 37.0 27.1 67.4 51.7 0.2 6.2 27.5 16.7 36.5 1.6 15.7 16.4 32.6 0.6 57.4 25.9 31.6 43.9 24.4 31.7 21.5 48.2 54.4 13.2 22.3 6.2 55.7 15.7 23.0 7.2 24.8 3.9 5.1 19.6 11.7 7.1 38.6 5.2 21.8 22.1 43.7 1.5 18.6 27.2 12.9 22.2 61.0 17.4 16.2 25.7 3.7 23.8 45.2 10.6 33.6 21.1 27.5 26.5 35.3 16.5 18.9 42.0 23.5 14.7 18.0 18.8 42.6 23.5 21.0 18.6 4.2 37.6 37.7 11.5 21.6 28.5 23.3 33.5 21.8 24.9 20.7 23.5 23.3 24.4 24.6 20.5 28.0 40.3 32.4 6.4 16.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 9.5 9.1 0.0 0.0 8.1 16.5 0.0 29.4 5.0 0.0 29.4 20.4 0.0 8.2 15.8 15.5 0.0 0.0 0.0 17.0 19.5 8.1 0.0 11.1 3.8 18.1 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 10.5 0.0 0.0 1.2 0.0 0.0 21.9 2.9 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 40.2 3.4 21.0 0.0 0.0 VPS39 "KIAA0770, VAM6" ENSG00000166887 "VPS39 subunit of HOPS complex" Q96JC1 15 42158701-42208307 "Plasma proteins, Predicted intracellular proteins" "Autophagy, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 57.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (4.39e-1)" "unprognostic (2.52e-1)" "unprognostic (1.28e-2)" "prognostic favorable (3.21e-7)" "unprognostic (9.85e-2)" "unprognostic (2.14e-2)" "unprognostic (3.40e-3)" "unprognostic (2.59e-2)" "unprognostic (2.71e-1)" "unprognostic (2.81e-2)" "unprognostic (1.01e-2)" "unprognostic (6.59e-2)" "unprognostic (1.85e-3)" "unprognostic (1.53e-1)" "unprognostic (4.51e-1)" "unprognostic (3.28e-2)" "unprognostic (5.04e-2)" 24.2 24.9 16.0 18.5 17.0 23.8 19.0 13.7 19.8 23.5 12.4 22.1 18.5 23.8 24.7 20.4 25.3 20.6 28.3 17.8 17.5 22.3 13.0 24.5 23.0 15.8 16.7 21.1 26.5 43.7 19.8 22.0 16.6 24.1 19.8 21.3 22.0 26.1 36.5 29.4 21.4 27.3 15.9 22.9 20.9 20.9 19.0 31.6 26.6 34.7 26.2 20.4 17.5 15.6 15.6 21.6 30.7 35.0 55.2 52.9 19.5 27.3 49.1 32.5 34.1 18.5 13.2 13.9 27.0 50.1 34.0 36.0 24.1 27.4 29.8 43.6 13.7 33.7 34.6 17.4 38.1 30.8 25.0 46.6 38.8 30.5 31.4 38.0 34.3 38.2 25.2 37.4 36.4 13.9 23.7 17.2 19.1 34.9 18.4 17.9 28.6 22.0 23.7 36.0 27.2 39.7 22.5 21.5 14.4 31.5 34.5 39.7 37.6 28.0 11.8 33.9 20.3 31.7 45.3 20.2 34.2 27.6 23.2 38.5 14.7 18.2 14.9 16.4 15.1 15.2 13.3 16.1 15.6 11.9 13.4 12.7 16.6 20.8 15.6 6.7 13.1 18.5 16.0 17.0 13.7 19.8 17.8 17.5 15.8 16.7 16.6 15.9 19.0 15.6 14.4 22.4 43.2 27.1 15.7 3.6 3.3 5.6 10.8 11.7 14.0 13.2 57.0 15.7 11.4 9.2 14.6 10.3 12.6 17.5 1.9 7.3 11.4 16.0 16.8 14.4 9.6 16.6 31.2 8.0 7.8 13.7 24.5 15.7 9.5 15.3 9.7 11.8 12.2 11.8 32.2 11.9 10.2 16.9 4.4 21.6 12.2 14.7 3.6 30.9 16.0 13.5 8.2 29.1 34.4 10.2 11.4 13.9 28.7 5.8 14.7 6.2 13.3 11.6 0.0 8.9 10.7 5.2 4.5 12.6 7.0 13.4 13.7 10.5 10.0 4.5 WASF3 "KIAA0900, SCAR3, WAVE3" ENSG00000132970 "WASP family member 3" Q9UPY6 13 26557683-26688948 "Cancer-related genes, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 60.0;retina: 56.4" "Cell type enhanced" "Detected in many" "Astrocytes: 161.6;Early spermatids: 104.1;Horizontal cells: 82.4;Inhibitory neurons: 127.5;Oligodendrocyte precursor cells: 69.9" "Cancer enhanced" "Detected in all" "glioma: 14.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037086, HPA066228" Enhanced NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "CAB037086: AB_1080585, HPA066228: " "unprognostic (1.42e-1)" "unprognostic (3.65e-2)" "unprognostic (2.25e-1)" "unprognostic (7.57e-2)" "unprognostic (8.23e-2)" "unprognostic (3.34e-1)" "unprognostic (6.19e-2)" "unprognostic (8.37e-2)" "unprognostic (8.98e-2)" "unprognostic (2.99e-1)" "prognostic favorable (2.21e-4)" "unprognostic (8.86e-3)" "unprognostic (2.93e-3)" "unprognostic (6.35e-2)" "unprognostic (2.12e-2)" "unprognostic (2.69e-3)" "unprognostic (9.18e-2)" 19.6 15.9 49.6 2.8 52.4 0.3 14.7 60.0 50.0 9.3 2.6 7.4 1.0 9.1 4.9 3.9 11.2 4.0 8.7 48.9 48.1 6.9 6.9 7.4 2.6 40.2 51.1 20.9 5.2 6.7 8.6 0.5 31.3 9.0 3.1 56.4 6.1 9.3 7.8 4.7 3.8 7.6 28.8 5.1 7.2 13.0 50.3 1.6 17.0 5.0 1.7 7.4 7.6 45.2 0.0 0.2 39.4 0.1 82.8 16.4 3.6 17.6 24.7 26.4 11.7 0.0 3.7 15.3 2.1 39.5 10.2 3.6 10.7 11.4 20.7 0.0 9.9 1.0 0.0 15.0 12.3 5.8 11.2 33.7 10.7 5.6 17.1 5.4 35.2 5.0 0.5 0.1 8.3 3.2 0.0 0.2 10.5 0.6 3.8 0.0 21.5 0.1 2.9 7.3 9.2 18.9 8.6 7.4 11.5 8.4 0.0 0.6 20.1 19.3 7.4 10.1 9.1 0.0 0.0 15.1 9.3 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 49.6 52.4 60.0 50.0 48.9 48.1 40.2 51.1 31.3 28.8 50.3 45.2 11.2 25.6 2.0 161.6 0.2 2.2 2.8 1.7 2.8 46.2 4.9 6.5 9.8 4.3 1.9 9.2 33.3 0.1 0.3 0.9 11.7 2.3 104.1 1.3 4.6 8.3 20.4 0.0 49.4 2.7 0.3 15.7 2.0 2.3 14.7 62.8 12.5 8.2 0.3 82.4 127.5 1.3 0.0 1.9 2.7 35.3 14.6 4.3 5.4 30.9 0.7 46.7 1.0 69.9 41.0 2.0 0.0 29.0 0.1 5.1 0.0 3.3 1.2 41.2 6.6 32.0 9.1 7.2 18.7 2.0 1.4 0.0 0.2 5.1 0.5 1.9 WBP1L "C10orf26, FLJ20154, OPAL1" ENSG00000166272 "WW domain binding protein 1 like" Q9NX94 10 102743948-102834516 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037635, HPA038371" Uncertain Approved Nucleoplasm,Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" Microtubules Nucleoplasm "HPA037635: AB_10672462, HPA038371: AB_2675980" "unprognostic (3.28e-2)" "unprognostic (6.46e-2)" "unprognostic (1.14e-2)" "prognostic favorable (4.03e-4)" "unprognostic (5.35e-3)" "unprognostic (2.73e-2)" "unprognostic (3.33e-2)" "unprognostic (1.25e-1)" "unprognostic (1.69e-1)" "unprognostic (2.43e-3)" "unprognostic (2.55e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.56e-6)" "unprognostic (2.34e-2)" "unprognostic (1.57e-1)" "unprognostic (4.88e-2)" "unprognostic (1.53e-1)" 34.9 43.2 21.3 22.3 23.1 5.0 25.8 20.7 20.1 26.4 28.7 27.7 15.2 27.4 18.9 21.1 29.4 25.1 24.1 19.8 22.4 20.8 42.1 24.5 21.4 32.0 23.9 26.5 15.5 41.7 22.9 23.5 23.6 26.9 15.0 5.7 22.6 22.4 54.6 37.5 19.9 26.2 25.9 21.3 25.7 14.2 24.7 33.7 41.1 49.0 18.9 24.5 20.5 22.6 21.0 26.8 14.5 24.5 47.0 37.9 29.5 21.0 56.7 20.5 25.8 18.3 31.9 18.1 27.8 32.5 16.5 22.7 10.7 18.2 15.5 18.3 11.3 36.6 11.6 13.3 30.3 17.8 41.7 41.2 32.0 26.4 20.3 47.0 40.5 21.6 18.1 22.0 35.6 27.5 21.7 19.8 11.0 16.1 12.9 42.9 38.3 11.7 18.2 20.4 3.4 13.9 11.5 11.6 24.1 26.0 47.2 19.5 30.4 19.6 20.1 22.3 19.1 40.6 22.9 13.0 27.7 33.6 8.8 7.8 12.2 16.2 8.7 14.8 7.0 6.5 7.3 8.4 8.7 6.1 6.5 6.9 15.2 12.9 19.4 5.4 8.2 10.6 21.3 23.1 20.7 20.1 19.8 22.4 32.0 23.9 23.6 25.9 24.7 22.6 13.3 22.4 19.0 29.4 12.2 8.2 8.0 17.0 11.4 6.4 25.0 15.4 15.7 12.8 17.8 12.9 0.0 33.9 17.2 26.4 1.9 14.2 2.0 9.7 11.0 20.4 9.1 11.1 24.6 25.3 14.6 29.3 16.8 12.7 38.1 16.4 27.1 56.2 27.7 13.5 26.4 14.6 14.2 46.6 13.1 1.8 13.1 28.8 10.6 40.3 28.9 9.8 29.9 19.1 26.3 24.6 13.7 19.5 9.0 29.9 18.3 8.9 20.5 3.8 19.7 16.6 17.7 4.4 5.8 11.3 11.8 40.0 14.4 8.9 12.2 11.3 WDR19 "DYF-2, FAP66, FLJ23127, IFT144, KIAA1638, NPHP13, ORF26, Oseg6, Pwdmp" ENSG00000157796 "WD repeat domain 19" Q8NEZ3 4 39182504-39285810 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 61.8;Inhibitory neurons: 82.5;Respiratory ciliated cells: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 45.3;ASC TERT1: 47.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039616, HPA058847" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Centrosome, Cytosol" "HPA039616: AB_10796331, HPA058847: AB_2683834" "unprognostic (1.80e-1)" "unprognostic (9.32e-2)" "unprognostic (6.40e-2)" "unprognostic (5.69e-2)" "unprognostic (1.37e-1)" "unprognostic (1.26e-3)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.06e-1)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "prognostic favorable (2.70e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (3.52e-2)" "unprognostic (2.40e-2)" "unprognostic (5.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.56e-2)" 7.5 8.0 3.1 5.3 2.5 3.7 9.2 5.3 3.8 10.5 10.8 6.8 1.9 16.0 13.3 3.9 20.3 8.4 4.2 2.3 2.5 8.8 6.3 8.8 4.7 5.3 3.6 17.9 5.4 8.1 9.1 6.2 2.9 7.7 4.2 13.0 5.7 8.4 2.3 5.5 4.7 9.1 3.5 4.6 6.2 14.0 2.7 6.9 16.7 2.4 4.9 6.2 6.8 3.6 6.1 5.2 10.3 12.1 45.3 47.0 4.7 7.5 17.2 8.1 10.6 2.8 6.5 10.4 4.1 7.8 17.2 4.0 10.9 5.4 8.6 0.5 8.5 2.2 10.3 6.1 16.1 9.6 2.6 30.5 11.1 11.9 7.2 24.6 10.7 11.0 8.7 9.1 9.9 2.1 7.7 8.1 3.5 3.7 5.6 8.2 10.4 4.2 7.0 2.9 11.5 10.4 10.2 2.4 6.1 13.1 5.5 3.6 7.9 7.9 5.3 17.5 7.8 7.2 7.6 7.6 11.9 3.3 3.7 0.1 0.3 0.2 0.3 0.5 0.3 0.8 0.5 0.6 0.3 1.2 0.5 0.6 0.3 0.8 0.5 0.1 0.3 0.2 3.1 2.5 5.3 3.8 2.3 2.5 5.3 3.6 2.9 3.5 2.7 3.6 5.5 12.8 9.3 26.1 5.4 4.8 4.9 4.6 2.2 10.1 7.3 7.4 4.5 2.8 9.4 18.4 10.4 1.2 1.8 0.7 0.0 5.5 5.1 32.3 14.6 6.7 2.4 4.0 61.8 3.6 3.2 10.8 2.0 12.0 2.5 13.4 4.2 10.0 3.2 25.2 82.5 2.0 12.2 3.2 3.6 3.4 16.4 3.0 1.8 19.7 1.8 6.7 1.0 18.1 19.7 2.9 0.2 18.8 3.9 3.0 0.3 4.0 46.6 21.7 0.0 10.9 7.9 33.8 10.2 3.9 4.7 1.4 2.9 13.1 1.1 1.9 WDR86 ENSG00000187260 "WD repeat domain 86" Q86TI4 7 151375909-151410727 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "cervix: 23.6;thyroid gland: 29.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 17.9;Endometrial ciliated cells: 13.9;Endometrial stromal cells: 22.5;Fibroblasts: 10.0;Microglial cells: 7.5;Muller glia cells: 11.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 14.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 13.7;NTERA-2: 2.6;SCLC-21H: 5.8;SH-SY5Y: 4.1;SuSa: 3.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (8.93e-3)" "unprognostic (1.83e-2)" "unprognostic (3.13e-4)" "unprognostic (1.59e-1)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (2.42e-2)" "unprognostic (1.34e-2)" "unprognostic (6.02e-2)" "unprognostic (1.14e-2)" "unprognostic (6.32e-3)" "unprognostic (2.20e-1)" "unprognostic (1.84e-6)" "unprognostic (7.22e-2)" "unprognostic (1.96e-1)" "unprognostic (2.35e-2)" "unprognostic (1.04e-1)" 10.9 1.3 7.0 0.3 4.9 0.1 8.1 0.2 5.4 23.6 6.6 10.5 0.8 9.1 0.2 1.4 19.2 0.9 0.6 5.1 0.4 3.0 0.8 1.3 1.1 2.5 3.3 6.2 0.9 7.6 8.0 2.9 0.9 4.1 0.1 0.4 1.3 4.7 0.5 0.7 3.1 0.4 1.4 18.5 5.8 0.8 0.5 0.2 29.1 0.0 0.1 2.2 6.6 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 4.1 0.0 0.0 0.0 3.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 7.0 4.9 0.2 5.4 5.1 0.4 2.5 3.3 0.9 1.4 0.5 0.4 3.4 0.0 0.5 2.6 1.3 0.0 0.2 1.9 1.2 0.3 3.4 17.9 1.4 0.0 1.5 0.0 0.0 0.9 0.7 0.0 0.0 0.0 0.0 13.9 22.5 1.5 0.0 0.0 1.8 0.0 1.4 10.0 0.5 3.1 0.0 0.7 0.4 0.2 0.5 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.2 0.5 0.0 7.5 1.2 11.5 1.0 1.5 0.2 0.0 0.0 3.0 0.4 0.0 0.0 0.0 5.4 0.8 0.0 0.2 4.6 0.1 0.5 0.0 0.3 0.8 3.1 0.1 0.0 0.3 WNT2B "WNT13, XWNT2" ENSG00000134245 "Wnt family member 2B" Q93097 1 112466541-112530165 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leydig cells: 80.2;Peritubular cells: 197.5" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.4;HSkMC: 8.0;SuSa: 3.4;TIME: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047274, HPA066368" Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA047274: AB_2732539, HPA066368: AB_2685664" "unprognostic (2.08e-3)" "unprognostic (2.06e-3)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (1.77e-1)" "unprognostic (1.49e-1)" "unprognostic (9.42e-2)" "unprognostic (4.90e-3)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (5.94e-2)" "unprognostic (1.13e-1)" "unprognostic (5.65e-4)" "unprognostic (5.41e-2)" "unprognostic (7.64e-2)" "unprognostic (4.80e-2)" "unprognostic (2.49e-2)" 4.5 1.9 2.0 1.5 4.9 0.1 2.8 2.1 2.8 8.2 2.0 5.6 3.0 4.9 2.8 5.8 4.7 2.8 4.3 1.9 1.7 2.4 1.0 6.3 0.8 1.8 1.7 10.9 1.8 0.6 2.3 4.8 1.9 6.1 5.3 5.5 2.2 13.9 1.6 11.1 5.2 2.2 1.4 1.7 3.8 3.8 1.8 0.2 1.9 0.8 0.7 5.6 9.1 2.3 0.4 0.3 2.2 0.5 2.2 4.4 0.4 1.0 1.0 0.2 0.4 0.2 0.5 1.1 0.2 1.1 0.2 1.4 0.7 0.3 0.2 0.0 0.4 0.1 0.8 0.3 1.8 0.2 0.5 8.0 0.8 0.4 0.1 1.3 1.2 0.3 0.1 0.2 0.2 0.3 0.1 0.1 0.3 0.0 0.3 0.1 0.3 0.0 1.5 0.3 0.3 0.3 0.7 0.1 0.7 3.4 0.0 0.2 3.5 0.3 1.4 0.8 0.3 0.1 0.1 0.0 0.9 0.1 0.9 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 2.0 4.9 2.1 2.8 1.9 1.7 1.8 1.7 1.9 1.4 1.8 2.3 7.6 12.8 3.3 2.0 2.0 10.1 1.8 6.1 5.2 14.1 2.1 0.9 6.5 1.5 3.9 1.8 27.1 2.1 2.4 3.5 0.0 0.8 5.6 2.6 3.6 10.2 8.4 2.1 5.5 1.4 0.8 17.7 1.1 6.8 2.5 2.8 6.1 0.2 1.1 5.0 6.2 2.2 4.1 2.1 8.2 3.4 80.2 4.0 3.6 30.9 2.2 9.8 0.0 11.6 7.1 2.0 4.8 197.5 2.5 4.4 2.9 0.9 4.6 27.6 0.0 9.7 2.7 5.9 5.5 26.4 13.9 1.9 1.9 2.0 1.5 2.6 XG PBDX ENSG00000124343 "Xg glycoprotein (Xg blood group)" P55808 X 2752040-2816500 "Blood group antigen proteins, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.5;skin 1: 38.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 14.4;Basal respiratory cells: 15.1;Basal squamous epithelial cells: 30.7;Fibroblasts: 30.1;Melanocytes: 10.6;Squamous epithelial cells: 10.1;Suprabasal keratinocytes: 21.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC diff: 63.7;ASC TERT1: 50.6;fHDF/TERT166: 31.5;hTCEpi: 49.6;T-47d: 28.2" "Low region specificity" "Detected in all" NA NA 22000 "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "prognostic unfavorable (4.25e-4)" "unprognostic (1.69e-2)" "unprognostic (1.40e-1)" "unprognostic (8.55e-3)" "unprognostic (1.89e-1)" "unprognostic (3.86e-2)" "unprognostic (4.50e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-2)" "unprognostic (8.62e-2)" "unprognostic (7.21e-2)" "unprognostic (2.30e-1)" "unprognostic (8.10e-6)" "unprognostic (3.96e-3)" "unprognostic (7.98e-2)" "unprognostic (5.83e-3)" "unprognostic (6.77e-3)" 17.5 0.0 0.0 0.1 0.0 1.2 8.9 0.1 0.0 12.0 0.0 0.3 0.1 1.2 0.0 11.7 0.8 3.3 2.6 0.1 0.1 0.3 0.7 0.6 0.3 0.3 0.2 0.2 0.1 0.1 0.1 1.8 0.2 0.8 0.1 0.0 7.6 0.6 3.2 38.6 0.1 0.2 0.3 0.1 0.3 0.1 0.0 2.2 1.9 5.0 3.1 2.1 12.7 0.7 0.1 0.0 0.0 0.1 63.7 50.6 0.6 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 31.5 0.0 5.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.1 49.6 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.2 4.2 0.1 28.2 0.0 0.1 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.2 0.2 0.3 0.0 0.7 3.3 0.0 0.0 1.0 0.0 14.4 0.5 15.1 30.7 0.0 0.2 0.4 0.4 0.0 1.3 1.8 0.0 0.8 0.5 0.0 0.0 0.0 0.0 2.4 0.5 0.8 0.0 1.3 0.9 0.0 0.1 30.1 0.0 1.2 0.0 6.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 9.0 0.0 0.0 0.1 10.6 1.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 2.5 2.5 0.2 0.5 10.1 21.9 0.5 0.5 0.5 0.0 0.2 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 166.6;kidney: 156.0" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 475.9" "Cancer enhanced" "Detected in many" "liver cancer: 18.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cell line enhanced" "Detected in some" "ASC diff: 8.2;ASC TERT1: 40.1;HSkMC: 21.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 13000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 7.5 0.9 0.1 3.7 0.1 0.2 3.0 0.1 0.1 3.7 0.1 5.5 99.0 2.4 0.1 2.2 6.3 4.3 5.3 0.1 0.1 156.0 23.1 2.1 0.5 0.2 0.1 1.8 0.3 0.3 0.1 1.2 0.1 1.8 6.3 0.0 1.5 0.4 0.5 4.4 166.6 6.0 0.1 0.3 3.4 0.1 0.1 1.0 1.4 2.4 0.4 7.8 4.0 0.1 0.0 0.0 0.5 0.0 8.2 40.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 4.3 1.4 1.2 0.0 1.3 2.8 0.2 0.2 0.4 2.0 0.1 0.0 2.8 0.4 1.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.2 0.5 11.4 5.9 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.2 0.0 0.0 10.0 1.1 0.0 0.0 0.0 0.4 18.5 0.8 0.0 0.3 12.8 0.0 1.0 3.6 0.0 0.0 1.0 1.8 1.0 0.0 0.0 3.1 0.0 0.1 0.0 21.0 0.0 0.1 0.0 475.9 75.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.0 1.2 0.9 0.0 8.4 0.0 ZBTB16 "PLZF, ZNF145" ENSG00000109906 "Zinc finger and BTB domain containing 16" Q05516 11 114059711-114256765 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 105.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 134.8;Inhibitory neurons: 125.9;NK-cells: 119.4;Skeletal myocytes: 163.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 23.3;MAIT T-cell: 39.4;naive B-cell: 11.0;NK-cell: 10.9" "Group enriched" "Detected in many" 5 "B-cells: 11.0;NK-cells: 10.9;T-cells: 39.4" "Cell line enhanced" "Detected in some" "ASC diff: 71.5;ASC TERT1: 38.6;HEL: 40.7;HHSteC: 26.6;HSkMC: 26.7;hTCEpi: 30.6;hTERT-HME1: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001499, CAB004540" Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB004540: AB_2218941, HPA001499: AB_1079640" "unprognostic (2.21e-1)" "unprognostic (2.17e-1)" "unprognostic (7.30e-2)" "unprognostic (1.18e-1)" "unprognostic (2.53e-1)" "unprognostic (3.05e-1)" "unprognostic (1.25e-2)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (8.79e-4)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "prognostic favorable (2.21e-4)" "unprognostic (2.57e-3)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (5.90e-2)" 55.8 20.8 5.1 3.4 14.9 7.6 32.3 11.7 24.8 25.9 17.7 20.9 0.9 29.6 4.0 28.1 30.9 13.1 28.1 9.9 8.4 10.6 14.5 27.1 8.8 20.1 8.4 51.4 61.7 34.3 6.4 9.6 15.2 15.1 3.3 2.2 13.3 7.0 88.6 28.5 16.3 15.8 4.9 13.2 18.3 4.0 7.1 6.5 29.3 105.8 2.0 29.4 19.7 18.0 0.0 0.0 13.0 0.0 71.5 38.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 40.7 0.0 0.0 26.6 0.9 0.7 26.7 30.6 0.0 25.6 0.0 4.6 5.5 0.1 0.0 0.8 0.0 2.2 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 4.2 1.2 23.3 1.2 39.4 0.4 1.2 3.5 0.1 11.0 1.3 0.6 0.3 10.9 1.2 0.0 0.4 5.7 5.1 14.9 11.7 24.8 9.9 8.4 20.1 8.4 15.2 4.9 7.1 18.0 95.3 22.4 7.7 59.1 16.3 11.1 81.7 7.7 8.6 32.6 12.6 16.8 35.1 42.9 7.1 9.2 0.0 0.1 51.2 0.7 1.9 1.9 21.1 1.7 41.3 49.5 7.2 18.1 134.8 0.9 0.2 59.8 1.1 3.8 14.5 38.2 65.7 50.9 0.8 0.0 125.9 3.7 8.2 27.0 5.3 27.7 89.8 32.1 7.2 65.6 7.6 20.2 119.4 45.8 43.4 0.3 0.1 92.2 17.7 38.6 28.8 6.6 6.8 1.9 105.2 163.9 75.3 0.4 9.9 1.8 6.8 0.3 27.8 0.2 3.5 9.4 ZBTB47 "DKFZp434N0615, KIAA1190, ZNF651" ENSG00000114853 "Zinc finger and BTB domain containing 47" Q9UFB7 3 42653697-42667580 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 112.5" "Cell type enhanced" "Detected in many" "Astrocytes: 21.9;Inhibitory neurons: 11.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 55.5;fHDF/TERT166: 30.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074057 Enhanced Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA074057: AB_2686657" "unprognostic (1.03e-1)" "unprognostic (1.15e-2)" "unprognostic (8.23e-2)" "unprognostic (3.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.95e-2)" "unprognostic (2.07e-1)" "unprognostic (1.23e-1)" "unprognostic (2.74e-1)" "unprognostic (2.00e-2)" "unprognostic (4.86e-2)" "unprognostic (8.99e-2)" "prognostic favorable (7.96e-5)" "unprognostic (5.77e-2)" "unprognostic (1.26e-1)" "unprognostic (4.57e-2)" "unprognostic (7.10e-2)" 23.2 13.7 74.4 9.3 69.3 2.7 17.9 52.6 65.3 21.5 32.9 29.3 3.9 23.0 4.5 11.5 15.2 11.4 70.3 61.0 54.0 9.4 6.2 14.0 2.7 70.5 63.8 15.3 13.4 9.9 12.3 6.2 58.2 23.5 3.3 6.5 17.4 14.5 112.5 16.4 11.2 14.8 59.9 7.2 18.7 9.1 70.8 2.0 19.4 63.1 1.8 23.7 15.9 81.2 6.7 5.9 3.6 2.4 55.5 20.7 1.2 15.1 12.7 6.5 4.7 1.3 2.7 0.1 6.4 30.9 2.5 1.6 0.9 5.9 1.2 0.0 7.2 3.7 18.9 1.6 17.5 0.1 5.3 23.5 10.4 8.5 7.1 17.0 7.3 0.0 3.9 4.8 12.9 1.7 0.2 0.5 2.1 0.2 3.5 5.0 6.7 1.9 3.4 1.3 4.0 6.7 7.3 1.2 6.0 1.5 8.3 8.6 17.3 14.1 8.2 13.9 6.4 0.2 0.0 0.0 13.1 4.8 4.3 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.1 74.4 69.3 52.6 65.3 61.0 54.0 70.5 63.8 58.2 59.9 70.8 81.2 1.8 0.0 1.1 21.9 0.0 4.0 1.5 3.6 3.4 6.4 0.8 0.9 10.5 0.0 1.8 1.8 0.0 0.1 1.6 0.1 0.0 0.7 10.0 0.5 4.5 2.1 0.0 0.0 7.8 1.3 0.2 6.4 4.6 1.2 4.5 2.9 2.2 0.7 1.4 0.0 11.8 0.3 2.0 1.9 4.1 2.5 3.4 2.0 8.8 8.4 0.8 7.7 0.0 9.0 11.5 0.6 1.2 3.0 1.9 2.0 0.0 0.6 1.1 1.9 0.0 7.8 4.4 0.0 0.2 1.3 3.1 0.1 0.4 5.9 0.0 1.1 ZCCHC24 "C10orf56, FLJ90798, Z3CXXC8" ENSG00000165424 "Zinc finger CCHC-type containing 24" Q8N2G6 10 79382325-79445624 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 148.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 66.0;Hepatic stellate cells: 64.2;Hepatocytes: 59.2;Leydig cells: 68.6;Oligodendrocyte precursor cells: 184.5;Oligodendrocytes: 130.6;Peritubular cells: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 135.0;ASC TERT1: 115.1;BJ hTERT+: 91.6;HSkMC: 120.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038348 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria Nucleoplasm "HPA038348: AB_10669538" "unprognostic (3.47e-3)" "unprognostic (8.70e-3)" "unprognostic (3.35e-1)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (7.28e-2)" "unprognostic (2.17e-2)" "unprognostic (2.25e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (3.76e-4)" "unprognostic (4.77e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (5.35e-6)" "unprognostic (1.84e-2)" "unprognostic (5.52e-2)" "unprognostic (2.85e-2)" "unprognostic (2.95e-3)" 40.4 11.9 119.7 13.8 147.7 2.6 32.5 112.0 109.7 42.3 44.8 67.7 6.2 42.8 8.9 14.0 34.1 23.8 35.7 89.4 101.0 8.7 33.1 22.7 7.5 134.9 145.8 26.4 8.4 4.0 9.4 16.1 120.3 32.2 8.9 3.7 12.0 27.2 58.0 13.7 18.2 36.1 119.7 10.9 25.5 8.9 136.8 2.7 18.4 26.5 4.3 43.2 22.9 148.0 3.3 3.1 10.4 9.0 135.0 115.1 2.5 24.6 91.6 14.2 16.5 2.6 0.1 0.1 13.1 49.5 5.0 0.3 1.7 0.6 11.9 6.2 6.5 1.3 7.2 3.1 35.1 3.8 2.0 120.5 1.3 12.8 3.5 42.1 2.9 0.9 4.8 5.3 12.3 1.1 0.1 14.9 2.5 0.6 30.1 0.6 12.3 2.2 1.7 4.0 0.3 12.9 7.7 0.9 31.5 9.7 3.5 7.0 2.0 13.6 12.4 37.4 8.5 9.2 6.5 0.1 27.9 4.9 49.4 0.0 0.6 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.1 0.1 119.7 147.7 112.0 109.7 89.4 101.0 134.9 145.8 120.3 119.7 136.8 148.0 36.2 0.0 2.6 29.0 1.4 7.6 1.4 1.5 1.8 0.1 5.6 5.7 20.2 5.7 1.2 0.0 0.0 0.6 4.5 0.3 0.0 0.8 2.0 2.3 66.0 29.5 0.0 4.4 0.3 0.8 0.9 40.9 5.1 2.6 1.3 4.1 64.2 59.2 10.7 0.0 0.5 0.4 0.0 17.1 14.5 4.8 68.6 7.4 16.0 30.0 5.6 16.7 1.0 184.5 130.6 0.9 0.1 65.5 5.0 2.9 0.0 1.8 1.2 1.1 13.1 38.7 24.0 0.7 1.7 1.4 4.5 1.5 3.6 8.9 0.1 1.3 ZDHHC1 "C16orf1, HSU90653, ZNF377" ENSG00000159714 "Zinc finger DHHC-type containing 1" Q8WTX9 16 67394152-67416833 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 84.6;Late spermatids: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.4;non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 11.4;ASC TERT1: 11.3;U-138 MG: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042531, HPA048659" Uncertain Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA042531: AB_2678041, HPA048659: AB_2680483" "unprognostic (8.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.05e-3)" "prognostic favorable (1.25e-6)" "unprognostic (1.68e-2)" "unprognostic (9.33e-2)" "unprognostic (6.03e-2)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" "prognostic favorable (5.99e-4)" "unprognostic (2.17e-1)" "prognostic favorable (1.55e-6)" "unprognostic (2.10e-1)" "unprognostic (1.59e-1)" "unprognostic (1.46e-1)" "unprognostic (5.63e-3)" 17.7 10.9 3.7 1.8 3.5 0.2 17.9 3.2 5.6 27.1 7.4 14.5 2.3 21.7 3.9 6.8 22.4 6.3 10.8 3.4 4.2 19.3 4.4 12.4 1.4 4.9 6.7 23.6 17.7 7.8 20.4 3.1 4.1 19.5 1.7 0.8 17.0 6.7 10.7 19.1 7.4 3.9 4.7 14.9 10.6 20.3 4.4 0.6 29.4 3.0 0.8 12.8 16.3 2.8 5.2 6.0 1.4 7.3 11.4 11.3 0.0 3.2 9.0 2.6 2.8 0.0 2.6 0.0 1.3 4.2 2.5 3.3 0.4 0.6 0.5 1.6 4.6 0.5 0.1 0.4 5.2 0.2 4.0 6.0 5.3 2.7 0.6 6.0 3.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 2.9 1.8 0.1 0.0 0.0 0.0 3.5 2.9 2.1 7.4 0.5 0.1 6.5 0.4 1.9 1.1 5.8 11.7 2.0 5.6 3.3 1.4 0.3 0.0 7.2 0.1 4.7 0.0 1.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.3 3.7 3.5 3.2 5.6 3.4 4.2 4.9 6.7 4.1 4.7 4.4 2.8 7.0 0.0 0.0 10.4 0.9 7.1 6.7 1.3 10.8 2.2 7.5 7.0 1.1 10.0 1.4 7.3 4.2 2.0 0.3 5.2 9.8 3.4 29.3 84.6 10.9 5.2 9.0 0.4 5.7 4.0 0.2 13.6 8.6 7.3 0.0 8.5 6.1 2.0 2.0 3.3 5.0 12.9 2.0 16.4 6.8 53.0 14.6 9.3 5.4 2.8 8.2 7.9 1.0 4.0 2.5 2.2 4.9 10.9 0.7 7.2 2.0 6.6 5.5 0.5 0.0 5.1 9.4 12.4 8.6 6.2 7.1 5.7 0.7 10.4 6.8 4.8 ZDHHC9 "CGI-89, CXorf11, DHHC9, ZDHHC10, ZNF379, ZNF380" ENSG00000188706 "Zinc finger DHHC-type palmitoyltransferase 9" Q9Y397 X 129803288-129843909 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 66.0;Oligodendrocytes: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031814 Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA031814: AB_10610700" "prognostic unfavorable (9.77e-5)" "prognostic unfavorable (4.64e-5)" "unprognostic (2.83e-2)" "unprognostic (7.53e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.01e-3)" "unprognostic (1.02e-1)" "unprognostic (4.04e-1)" "unprognostic (3.49e-2)" "unprognostic (9.70e-3)" "unprognostic (4.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" "unprognostic (1.17e-2)" "unprognostic (4.11e-2)" 28.2 12.0 39.2 10.2 66.6 5.4 24.3 46.5 52.5 19.1 23.3 22.0 31.6 11.8 11.7 15.6 12.1 15.3 15.5 39.2 49.0 37.1 40.1 26.7 3.3 60.5 58.2 11.2 25.9 25.2 11.4 17.2 52.5 18.8 24.9 6.0 21.1 11.3 13.4 35.3 34.0 15.3 44.8 3.9 19.5 4.1 57.8 3.6 13.8 11.3 6.6 23.8 14.5 78.6 45.9 23.8 33.2 67.5 112.4 87.7 27.0 44.3 50.6 20.9 26.0 37.6 58.4 1.6 73.7 47.6 54.0 30.4 38.0 44.6 30.0 2.6 23.7 9.2 24.0 50.1 44.4 6.1 15.7 96.0 71.1 34.0 50.1 36.5 39.9 15.0 10.1 17.6 34.0 40.0 8.8 11.4 18.0 102.3 40.4 8.2 21.4 27.1 30.1 25.2 26.3 22.0 12.7 64.7 20.5 38.9 27.6 10.1 32.8 21.1 7.3 50.0 36.3 16.5 12.7 5.5 37.9 25.1 10.8 0.0 2.2 1.8 3.0 2.0 3.7 2.7 3.6 2.9 2.4 1.5 4.5 2.6 0.0 2.5 5.2 5.1 1.8 2.1 39.2 66.6 46.5 52.5 39.2 49.0 60.5 58.2 52.5 44.8 57.8 78.6 66.0 22.4 28.6 4.6 2.8 18.6 12.4 12.8 13.1 9.1 16.8 15.1 4.6 17.2 15.9 46.0 2.1 5.6 2.7 20.1 3.9 18.6 1.8 23.8 16.9 16.6 18.0 4.2 10.5 19.8 19.1 32.7 18.3 59.7 2.5 11.5 7.9 43.7 4.9 1.7 11.8 23.2 10.2 3.5 12.2 2.0 12.2 3.9 10.6 7.5 0.3 1.5 1.0 9.5 118.2 33.5 14.6 7.5 7.7 39.1 51.0 25.8 7.2 2.8 0.0 9.5 11.1 8.4 8.7 16.9 19.2 10.3 5.1 7.5 27.2 22.1 ZFP36L2 "BRF2, ERF2, RNF162C, TIS11D" ENSG00000152518 "ZFP36 ring finger protein like 2" P47974 2 43222402-43226606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Developmental protein, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1727.3;Basal squamous epithelial cells: 2181.9;Plasma cells: 2029.3;Suprabasal keratinocytes: 1549.6;T-cells: 1760.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047428 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA047428: AB_10963428" "unprognostic (2.07e-2)" "unprognostic (1.81e-2)" "unprognostic (9.77e-2)" "unprognostic (6.10e-2)" "unprognostic (9.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-1)" "unprognostic (7.62e-3)" "unprognostic (2.04e-1)" "unprognostic (4.50e-2)" "unprognostic (9.67e-3)" "unprognostic (1.65e-1)" "unprognostic (1.96e-2)" "unprognostic (2.50e-1)" "unprognostic (4.52e-2)" "unprognostic (1.23e-1)" "unprognostic (2.98e-2)" 187.0 110.8 33.0 150.1 39.9 195.2 175.0 41.0 31.9 141.5 36.9 130.3 113.6 101.7 38.7 103.7 121.1 124.1 97.6 28.5 45.6 64.7 91.4 169.7 171.1 109.1 50.3 187.4 78.7 19.9 37.7 31.7 51.9 123.1 132.5 17.0 92.5 63.8 64.9 219.9 171.2 65.2 58.5 120.7 127.2 19.2 51.5 160.9 180.8 42.1 121.9 93.5 133.7 45.7 36.2 17.4 17.0 9.5 208.0 211.4 6.9 51.7 93.1 21.6 16.4 61.0 16.7 26.0 37.9 59.7 12.0 66.9 18.2 89.9 18.3 46.6 38.0 42.0 6.4 65.1 61.8 92.3 35.0 149.8 143.4 22.1 143.2 32.6 38.9 39.1 42.6 100.1 21.4 192.0 109.4 190.8 26.0 113.2 30.1 81.0 12.7 151.7 36.9 51.5 15.0 37.6 9.8 58.9 32.2 23.2 10.0 150.4 18.6 58.3 25.2 49.7 32.1 84.1 25.1 39.0 19.6 227.7 27.5 18.7 42.5 82.1 46.6 35.3 45.8 18.1 46.1 62.8 51.2 22.7 34.1 33.9 61.6 52.7 28.1 22.0 19.5 30.0 33.0 39.9 41.0 31.9 28.5 45.6 109.1 50.3 51.9 58.5 51.5 45.7 540.1 48.1 67.1 91.1 1144.2 1727.3 1232.0 76.3 2181.9 3.7 455.0 420.5 120.8 420.4 72.4 136.1 0.0 12.2 1167.2 470.8 84.1 37.2 2.4 192.4 241.9 371.7 187.8 340.6 0.4 37.0 22.2 635.9 562.7 292.0 138.5 497.7 185.6 146.8 236.5 0.0 0.6 538.1 26.4 436.2 435.2 12.5 311.9 579.7 302.4 97.4 318.5 214.2 620.0 29.7 13.8 41.1 378.8 259.9 2029.3 590.1 319.2 81.4 48.2 30.5 105.2 631.8 246.5 3.4 27.8 534.9 1549.6 17.0 1760.1 342.5 581.4 238.0 ZNF106 "SH3BP3, ZFP106, ZNF474" ENSG00000103994 "Zinc finger protein 106" Q9H2Y7 15 42412823-42491141 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 392.5;tongue: 465.5" "Cell type enriched" "Detected in all" 9 "Cardiomyocytes: 1836.4" "Cancer enhanced" "Detected in all" "melanoma: 29.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 161.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054267 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoli "Nucleoplasm, Cytosol" "HPA054267: AB_2682431" "unprognostic (2.15e-2)" "unprognostic (3.31e-1)" "unprognostic (7.10e-2)" "unprognostic (2.61e-2)" "unprognostic (4.01e-2)" "unprognostic (1.34e-1)" "unprognostic (9.32e-2)" "unprognostic (2.49e-1)" "unprognostic (3.96e-1)" "unprognostic (1.33e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (1.76e-3)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (4.36e-1)" "unprognostic (4.09e-3)" 32.4 11.2 20.8 14.3 29.8 24.4 17.9 19.0 28.1 18.0 109.2 19.7 10.0 15.9 17.3 18.5 12.7 17.2 175.6 23.3 22.6 16.5 8.7 20.9 17.5 23.6 29.1 15.9 10.3 17.8 10.3 12.9 22.5 20.9 13.9 22.0 12.9 14.7 392.5 11.7 13.3 23.0 20.8 17.1 12.8 14.3 27.4 15.6 13.2 465.5 18.6 14.6 9.1 27.7 27.2 15.1 29.0 33.5 86.8 68.5 16.1 21.7 22.2 19.6 20.5 33.9 7.8 17.8 19.0 27.7 22.8 31.8 28.3 23.4 29.5 29.0 13.1 34.7 37.9 13.6 23.2 43.1 20.2 55.4 17.8 28.0 32.6 19.5 32.3 23.2 43.0 2.7 36.9 11.9 16.2 13.3 11.0 26.1 15.1 15.2 54.3 10.8 12.1 31.5 16.5 10.2 45.0 22.8 28.7 23.4 20.0 30.0 42.2 20.8 32.5 26.1 32.3 14.8 32.2 76.5 18.4 33.6 37.6 86.8 63.8 27.1 15.6 52.3 13.5 21.8 13.0 13.3 35.6 26.8 11.3 10.6 161.0 12.5 66.8 36.0 13.0 18.0 20.8 29.8 19.0 28.1 23.3 22.6 23.6 29.1 22.5 20.8 27.4 27.7 58.0 134.6 107.7 46.0 49.6 38.5 57.9 41.9 44.3 58.5 50.9 46.0 1836.4 62.9 57.0 29.5 95.9 37.9 67.2 31.7 41.1 43.2 197.2 75.2 67.1 69.9 40.2 50.5 73.3 42.4 39.3 141.7 31.1 37.5 44.9 49.5 62.8 40.1 53.5 35.3 62.9 32.6 32.6 132.7 43.4 105.2 37.6 89.8 65.8 47.8 124.3 53.6 66.9 31.2 34.2 65.7 26.9 92.6 50.7 74.8 39.7 41.5 161.1 79.9 46.0 151.2 70.0 62.3 38.1 49.8 29.8 30.6 46.0 85.9 36.6 68.2 ZNF436 "KIAA1710, Zfp46" ENSG00000125945 "Zinc finger protein 436" Q9C0F3 1 23359448-23369836 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 22.2;Squamous epithelial cells: 22.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 18.8;HSkMC: 34.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043817 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "HPA043817: AB_10794774" "unprognostic (1.50e-1)" "unprognostic (2.91e-1)" "unprognostic (1.44e-1)" "unprognostic (1.93e-1)" "unprognostic (8.10e-2)" "unprognostic (2.12e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.86e-1)" "unprognostic (1.09e-2)" "unprognostic (1.76e-1)" "unprognostic (1.92e-1)" "unprognostic (9.51e-3)" "unprognostic (5.04e-2)" "unprognostic (3.22e-1)" "unprognostic (1.06e-1)" "unprognostic (7.75e-3)" 10.0 14.8 4.8 2.3 5.2 1.4 9.8 5.5 5.4 9.8 4.5 8.5 3.1 9.9 8.0 16.5 6.9 5.5 8.3 5.5 5.3 4.0 3.7 4.2 2.7 6.3 5.2 15.4 6.9 5.3 4.4 4.2 5.6 9.5 3.1 4.6 14.6 5.1 6.5 12.6 5.6 6.2 5.6 7.0 6.1 7.9 5.4 3.5 9.0 6.2 3.6 10.4 10.2 5.9 3.8 2.4 8.6 4.5 9.1 18.8 4.1 3.4 4.6 4.3 5.0 1.4 3.3 2.6 3.8 4.9 2.8 4.8 15.0 5.7 4.6 3.2 3.3 2.8 5.3 2.2 3.6 1.2 1.9 34.9 8.0 3.6 4.1 7.8 6.2 3.1 3.4 1.8 4.5 1.8 2.9 2.1 0.3 1.7 3.8 3.8 3.6 2.5 3.4 9.5 3.9 4.9 9.6 4.7 3.7 2.9 2.6 1.4 5.0 3.7 2.7 2.9 1.9 2.8 3.6 2.1 2.9 2.3 2.9 0.0 0.7 0.7 0.7 0.8 0.7 0.4 0.5 0.8 1.1 0.5 0.8 0.7 0.5 2.6 0.8 0.1 0.9 0.6 4.8 5.2 5.5 5.4 5.5 5.3 6.3 5.2 5.6 5.6 5.4 5.9 7.8 0.0 0.5 2.6 2.0 5.2 1.6 1.9 22.2 4.1 6.9 5.0 6.4 1.5 1.6 5.5 6.2 3.8 2.6 3.5 0.0 2.9 2.3 5.0 8.5 14.0 3.6 1.7 4.2 4.9 1.8 9.6 2.0 7.8 0.0 9.4 3.3 3.1 2.1 10.1 3.3 4.6 2.0 1.9 3.8 1.5 9.9 2.1 5.4 0.0 4.5 9.3 2.1 2.5 3.1 3.6 5.9 11.7 2.1 3.3 4.0 2.8 2.4 2.4 0.0 4.5 4.5 5.5 6.9 22.1 9.7 2.9 2.4 7.9 3.1 2.0 ZNF540 DKFZp547B0714 ENSG00000171817 "Zinc finger protein 540" Q8NDQ6 19 37551406-37614179 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 25.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.3;Excitatory neurons: 47.7;Inhibitory neurons: 56.5;Oligodendrocyte precursor cells: 23.1;Oligodendrocytes: 27.7;Rod photoreceptor cells: 22.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 3.0" HPA003444 Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Vesicles, Cytosol" "HPA003444: AB_1080732" "unprognostic (2.51e-2)" "unprognostic (2.30e-4)" "unprognostic (4.92e-2)" "unprognostic (1.12e-1)" "unprognostic (2.80e-4)" "unprognostic (4.24e-4)" "unprognostic (3.44e-3)" "unprognostic (8.88e-4)" "unprognostic (2.65e-1)" "unprognostic (3.17e-1)" "unprognostic (3.38e-5)" "unprognostic (1.50e-1)" "unprognostic (1.09e-6)" "unprognostic (2.74e-1)" "unprognostic (4.75e-2)" "unprognostic (8.08e-2)" "unprognostic (8.33e-5)" 1.6 4.9 10.5 2.3 10.2 0.6 3.1 14.4 11.2 5.0 6.8 4.4 2.1 3.3 4.8 1.6 3.9 1.8 5.3 9.4 12.3 5.0 2.2 2.6 3.8 8.2 8.9 8.5 2.5 5.3 14.7 1.1 8.6 5.5 1.8 25.8 3.5 4.6 2.0 3.2 4.2 1.8 7.9 4.7 3.2 2.9 11.4 2.1 7.9 1.6 3.4 3.6 3.4 9.1 0.1 0.0 1.1 1.3 3.0 1.8 0.1 0.4 0.4 0.5 0.9 0.1 0.0 0.5 0.1 1.1 0.3 0.4 0.8 0.4 0.4 1.7 1.2 0.4 0.8 0.0 0.8 0.5 0.9 0.9 1.1 0.3 0.0 0.2 0.0 2.4 0.2 0.0 0.7 0.0 0.8 0.3 0.4 0.1 0.2 0.7 0.7 0.4 0.2 0.1 1.2 1.4 0.4 0.1 0.1 0.8 0.6 0.5 0.0 0.4 1.4 0.5 0.4 1.6 1.0 1.3 0.0 0.2 0.2 0.0 0.0 0.8 2.7 0.0 2.6 1.9 2.7 3.0 0.1 2.2 4.4 4.8 0.1 2.4 0.0 0.2 3.1 1.2 10.5 10.2 14.4 11.2 9.4 12.3 8.2 8.9 8.6 7.9 11.4 9.1 2.3 3.2 2.6 15.3 6.3 1.7 1.3 0.8 3.4 23.3 2.4 2.2 10.4 0.0 1.7 1.8 6.2 0.3 3.3 0.2 7.9 0.3 18.6 1.1 1.0 2.2 0.0 0.0 47.7 0.4 0.4 2.8 1.5 0.6 3.8 1.7 2.2 1.1 0.8 18.5 56.5 0.3 0.0 0.8 1.0 5.5 2.5 1.0 3.6 11.2 0.5 5.5 8.2 23.1 27.7 0.2 1.1 5.7 2.5 0.4 2.3 2.7 0.4 22.3 6.6 3.1 2.9 5.7 3.3 1.8 1.3 0.1 3.9 1.2 0.3 0.2 ZNF843 MGC46336 ENSG00000176723 "Zinc finger protein 843" Q8N446 16 31432593-31443160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 4.6;Cardiomyocytes: 5.3;Prostatic glandular cells: 3.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 2.3;EFO-21: 1.8;HMC-1: 1.6" "HPA030911, HPA030912, HPA077945" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nuclear speckles" "HPA030911: AB_2673656, HPA030912: AB_10670434, HPA077945: " "unprognostic (9.27e-2)" "unprognostic (1.32e-1)" "unprognostic (3.43e-3)" "unprognostic (9.24e-2)" "unprognostic (1.33e-1)" "unprognostic (6.25e-3)" "unprognostic (2.86e-1)" "unprognostic (8.30e-3)" "unprognostic (3.55e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-3)" "unprognostic (2.93e-3)" "unprognostic (5.96e-3)" "unprognostic (1.23e-2)" "unprognostic (7.66e-2)" "unprognostic (1.28e-5)" "unprognostic (1.17e-1)" 0.6 0.5 1.5 0.3 1.2 0.3 0.6 2.5 1.3 1.0 0.0 0.4 0.2 1.0 0.7 0.4 1.1 0.7 1.7 1.6 1.9 0.6 0.4 0.3 0.3 1.1 1.4 3.0 2.1 0.9 1.5 0.4 0.9 0.6 0.1 1.1 1.5 0.8 2.2 0.9 0.3 0.5 1.1 0.4 0.4 0.5 1.8 0.2 1.0 0.8 0.2 0.5 0.6 0.9 0.1 0.3 0.2 1.2 2.3 0.6 0.0 0.2 0.2 0.0 0.1 0.1 0.3 0.0 1.8 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.6 0.2 1.6 1.2 0.3 0.0 0.1 0.8 0.0 0.2 0.2 0.2 0.6 0.8 0.1 0.4 0.7 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.7 0.1 0.3 0.2 0.1 0.2 0.0 0.2 0.2 0.8 0.0 0.2 0.1 0.1 0.0 0.1 0.4 1.0 0.2 0.2 0.7 0.1 0.4 0.2 0.2 0.7 0.1 0.2 0.1 0.4 0.7 1.7 0.1 0.2 0.1 1.0 1.5 1.2 2.5 1.3 1.6 1.9 1.1 1.4 0.9 1.1 1.8 0.9 0.5 0.0 0.5 2.9 0.3 0.8 4.6 0.1 0.0 2.2 0.9 1.3 5.3 0.0 0.7 0.0 2.1 0.3 0.1 0.3 0.0 0.3 0.2 0.4 2.0 1.0 1.2 0.0 1.4 0.2 0.1 1.4 0.0 0.4 1.3 1.4 1.8 0.3 0.6 0.0 1.7 0.0 0.0 0.3 2.1 0.0 1.5 0.9 0.0 0.0 0.1 1.4 2.1 1.0 1.3 0.1 0.1 1.5 0.1 3.6 0.0 0.4 0.0 1.9 0.0 2.8 1.3 0.4 0.7 0.1 1.4 0.3 1.2 0.8 0.1 1.9 ZNF846 ENSG00000196605 "Zinc finger protein 846" Q147U1 19 9751993-9793180 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 242.1;Late spermatids: 91.0;Spermatocytes: 177.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA034617, HPA034618" Approved Approved "Actin filaments" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Actin filaments" "HPA034617: AB_10603942, HPA034618: AB_2674249" "unprognostic (1.36e-1)" "unprognostic (4.70e-2)" "unprognostic (1.82e-1)" "unprognostic (2.79e-2)" "unprognostic (6.73e-2)" "prognostic favorable (5.25e-8)" "unprognostic (2.57e-1)" "unprognostic (2.62e-2)" "unprognostic (2.96e-2)" "unprognostic (2.33e-3)" "unprognostic (1.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.31e-2)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (1.32e-1)" "unprognostic (9.05e-3)" 7.9 6.6 9.3 6.2 8.9 4.5 7.0 6.5 9.1 8.5 6.6 8.2 4.2 11.1 9.6 9.2 8.5 9.7 8.2 7.2 8.0 5.0 4.6 6.9 8.1 9.5 10.2 12.9 3.9 7.3 5.5 6.3 8.5 11.8 7.2 7.4 7.1 18.7 5.4 8.0 5.3 10.6 9.2 6.4 6.6 14.0 8.9 8.0 7.3 5.7 6.3 13.1 8.9 10.3 3.8 0.8 11.6 2.8 12.8 16.4 2.6 5.8 4.0 4.1 8.2 2.1 3.1 1.5 2.3 6.9 4.8 1.4 0.8 4.5 4.5 3.4 2.5 8.6 0.3 3.1 4.6 0.8 8.9 16.9 5.9 3.1 2.4 9.4 3.4 4.6 1.5 0.0 4.4 1.5 3.1 7.2 1.7 3.1 4.8 4.5 0.9 0.4 5.2 14.6 1.8 3.5 3.1 0.3 4.4 4.0 1.9 6.0 1.8 3.3 2.4 2.8 0.5 6.5 7.3 8.3 0.4 1.1 2.9 1.1 2.1 1.3 1.7 1.7 3.5 4.2 2.6 4.3 6.9 5.2 2.0 4.2 0.8 2.2 1.2 4.5 3.3 1.6 9.3 8.9 6.5 9.1 7.2 8.0 9.5 10.2 8.5 9.2 8.9 10.3 4.4 9.6 5.4 18.3 4.7 7.9 15.0 14.5 20.5 1.7 7.3 10.0 6.8 5.7 11.9 0.0 2.1 1.6 5.5 5.4 9.8 6.5 242.1 6.4 7.7 5.1 1.2 4.8 25.8 4.9 2.1 7.8 5.1 4.5 5.1 7.8 5.7 5.4 7.5 0.0 13.7 4.9 6.1 13.9 9.1 91.0 6.8 10.2 7.2 41.2 9.2 3.2 1.0 14.6 14.6 7.0 3.9 9.1 3.7 7.3 3.1 6.1 12.5 2.4 6.6 3.7 8.2 177.1 8.6 8.0 8.8 1.2 5.2 7.8 4.1 16.4