Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCA6 EST155051 ENSG00000154262 "ATP binding cassette subfamily A member 6" Q8N139 17 69078702-69141895 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 77.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.5;Fibroblasts: 117.6;Hepatocytes: 110.3;Inhibitory neurons: 77.8;Leydig cells: 51.3;Microglial cells: 93.7;Theca cells: 45.4" "Cancer enriched" "Detected in some" 7 "liver cancer: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 39.9;ASC TERT1: 56.0;HSkMC: 25.3;HUVEC TERT2: 54.8;RT4: 14.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA064878, HPA067180" Enhanced Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA064878: AB_2685380, HPA067180: AB_2685797" "unprognostic (7.76e-2)" "unprognostic (6.80e-2)" "unprognostic (2.12e-1)" "unprognostic (8.01e-2)" "unprognostic (8.47e-2)" "unprognostic (9.82e-3)" "prognostic favorable (3.29e-4)" "unprognostic (1.35e-1)" "unprognostic (6.60e-2)" "unprognostic (3.00e-2)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (7.96e-4)" "unprognostic (1.61e-4)" "unprognostic (2.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.69e-1)" 23.3 5.5 1.3 2.6 5.5 0.0 15.9 5.1 3.2 10.5 3.1 8.0 2.2 5.9 2.8 5.9 11.3 10.1 17.5 1.1 4.1 3.6 77.9 10.9 5.0 14.3 3.0 29.8 2.3 1.3 2.1 2.1 9.4 2.9 4.4 0.8 9.0 2.0 5.4 6.6 5.5 3.7 7.1 1.5 5.7 1.8 3.4 1.4 8.6 11.7 3.2 14.2 8.9 21.3 0.0 0.0 0.0 0.0 39.9 56.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 25.3 0.1 3.2 0.9 1.5 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 2.5 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 5.5 5.1 3.2 1.1 4.1 14.3 3.0 9.4 7.1 3.4 21.3 12.5 0.0 0.0 2.9 2.0 3.1 1.5 0.4 4.0 11.6 1.8 2.2 6.0 4.3 0.9 3.7 6.2 0.0 1.7 1.8 0.0 0.5 3.3 0.7 5.1 3.2 2.4 2.7 62.5 0.2 0.0 117.6 2.0 2.5 0.0 4.0 3.3 110.3 1.6 0.0 77.8 0.7 0.0 2.5 42.1 2.7 51.3 20.3 5.4 93.7 0.7 3.2 0.0 4.5 33.4 0.4 1.1 12.0 1.2 0.1 0.5 0.9 0.7 13.3 0.0 20.0 14.3 2.0 0.9 1.4 2.8 0.0 1.2 45.4 0.3 0.5 ABCD4 "EST352188, P70R, PMP69, PXMP1L" ENSG00000119688 "ATP binding cassette subfamily D member 4" O14678 14 74285269-74303055 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003396 Approved NA NA "Cluster 35: T-regs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "HPA003396: AB_1078078" "unprognostic (3.92e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-3)" "unprognostic (5.86e-2)" "unprognostic (3.69e-1)" "unprognostic (1.67e-1)" "unprognostic (5.72e-2)" "unprognostic (4.34e-2)" "unprognostic (3.46e-2)" "unprognostic (4.63e-2)" "unprognostic (2.21e-3)" "unprognostic (5.26e-2)" "unprognostic (2.35e-2)" "unprognostic (1.25e-1)" "unprognostic (6.69e-2)" "unprognostic (7.45e-3)" "unprognostic (7.93e-3)" 6.6 4.7 3.0 3.9 3.4 4.6 6.4 4.0 5.4 5.8 2.9 5.4 8.8 4.9 2.1 4.8 8.5 7.7 6.0 3.0 3.3 5.4 7.7 5.8 6.6 4.2 3.4 6.9 6.0 3.8 3.9 7.4 3.7 3.6 4.0 3.3 4.0 3.5 3.9 4.1 8.7 5.2 2.8 6.2 4.5 3.4 3.6 5.5 7.2 2.0 3.8 4.5 4.3 4.5 2.6 3.1 7.9 6.2 6.4 4.3 9.8 3.9 5.6 5.8 6.0 6.5 13.7 4.3 7.4 5.9 3.2 9.2 6.0 5.4 3.0 3.9 3.8 2.3 5.1 5.2 2.1 2.9 4.4 10.4 2.4 4.1 2.8 3.0 9.9 5.4 4.3 1.9 4.5 4.3 7.1 5.6 3.0 5.0 5.9 9.7 11.4 6.3 8.6 8.5 3.7 7.3 5.4 5.3 5.5 3.7 12.3 1.7 9.7 3.6 7.0 3.2 2.5 4.4 4.5 3.3 5.1 4.3 4.5 6.0 1.3 1.8 2.6 1.2 1.7 1.9 2.2 2.9 2.1 1.8 1.2 1.8 1.1 2.6 1.0 4.0 5.2 1.4 3.0 3.4 4.0 5.4 3.0 3.3 4.2 3.4 3.7 2.8 3.6 4.5 50.0 28.9 18.6 32.3 16.7 15.6 14.8 23.0 12.0 46.5 21.4 14.2 9.7 34.3 21.2 20.2 64.6 51.6 28.9 31.4 9.8 25.3 10.3 27.9 23.5 50.2 12.0 9.9 29.6 11.3 19.9 23.0 13.7 20.1 20.3 43.2 44.6 23.3 51.1 32.0 34.7 15.7 18.3 24.8 27.1 7.7 40.4 19.5 21.4 20.6 22.8 36.4 32.0 23.6 38.1 17.9 19.4 25.2 13.3 12.6 60.1 23.9 19.5 55.5 32.9 23.3 19.1 35.8 27.2 10.6 10.7 28.5 23.4 27.9 22.9 16.7 ABI3 "NESH, SSH3BP3" ENSG00000108798 "ABI family member 3" Q9P2A4 17 49210411-49223225 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 69.5" "Cell type enhanced" "Detected in many" "dendritic cells: 82.7;Kupffer cells: 130.7;Macrophages: 71.4;monocytes: 66.0;NK-cells: 249.3;T-cells: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 735.0;non-classical monocyte: 788.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 49.9;HDLM-2: 28.8;HUVEC TERT2: 76.0;RH-30: 18.6;TIME: 59.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA017345, HPA064805" Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA017345: AB_2669592, HPA064805: " "unprognostic (1.24e-1)" "unprognostic (1.23e-2)" "unprognostic (2.18e-2)" "prognostic favorable (7.13e-4)" "unprognostic (1.56e-1)" "unprognostic (1.16e-3)" "unprognostic (5.29e-1)" "unprognostic (8.25e-2)" "unprognostic (3.63e-2)" "unprognostic (1.48e-1)" "unprognostic (3.47e-2)" "unprognostic (1.82e-1)" "unprognostic (2.28e-3)" "unprognostic (1.03e-1)" "unprognostic (9.24e-3)" "unprognostic (4.16e-2)" "unprognostic (2.40e-1)" 10.2 8.1 7.5 21.9 8.8 6.4 8.1 10.6 11.2 6.9 6.9 7.7 10.9 7.3 1.9 5.1 7.4 7.6 12.8 8.2 13.0 10.6 7.0 17.3 30.1 20.5 12.4 3.0 4.1 3.6 4.2 6.3 15.4 8.0 7.4 0.7 4.5 3.6 3.8 4.6 18.1 8.0 15.5 69.5 8.4 1.2 14.1 10.0 8.9 6.8 28.6 7.8 6.2 17.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.9 1.9 3.1 5.2 0.4 0.0 49.9 0.6 0.1 0.0 0.0 0.0 0.0 4.9 28.8 0.0 0.2 0.2 0.0 0.0 0.5 0.2 0.1 0.0 1.4 0.1 0.0 76.0 2.7 0.0 0.0 0.5 0.0 10.1 7.3 3.2 0.0 0.0 8.2 18.6 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.4 59.3 0.1 11.2 0.0 0.0 0.6 2.6 8.4 0.0 0.5 0.1 1.4 117.2 3.2 290.2 735.0 141.2 36.1 51.8 189.2 248.5 27.3 31.4 141.0 17.9 110.8 788.6 9.8 33.5 234.0 7.5 8.8 10.6 11.2 8.2 13.0 20.5 12.4 15.4 15.5 14.1 17.2 25.5 0.0 6.4 1.0 20.5 1.9 0.1 0.0 0.0 0.0 0.8 1.8 1.5 2.8 0.0 0.0 0.0 0.3 82.7 0.2 50.9 0.1 0.4 0.1 0.3 39.4 1.2 6.9 0.2 0.2 0.5 2.4 2.6 0.2 7.0 0.1 39.7 1.6 45.7 0.0 0.2 0.0 0.0 130.7 21.4 0.7 0.3 71.4 1.8 2.8 66.0 0.1 249.3 0.0 0.0 0.0 0.0 0.0 14.7 0.2 0.0 0.4 0.7 0.4 0.0 0.8 2.1 0.2 0.4 0.0 4.3 0.3 58.0 0.5 0.1 0.2 ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Fibroblasts: 213.8;Leydig cells: 97.3;Muller glia cells: 93.7;Skeletal myocytes: 106.8" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 437.3;hTEC/SVTERT24-B: 840.8;hTERT-HME1: 818.4;TIME: 1405.8;U-2197: 311.0" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" NA NA 550000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" 41.3 9.9 3.9 57.0 9.7 0.2 23.1 0.8 4.1 56.4 3.1 36.5 5.3 49.5 10.7 35.1 46.9 97.9 44.5 3.8 26.6 12.2 7.8 68.7 25.9 3.4 5.7 89.4 12.7 3.0 4.7 51.9 7.3 8.7 56.2 57.5 13.7 12.3 6.7 14.0 15.4 72.0 5.6 12.4 25.5 17.1 6.7 7.9 25.0 41.1 39.9 96.7 23.7 9.1 1.3 0.3 0.1 0.0 37.0 437.3 0.4 91.9 90.2 171.4 79.9 0.0 0.2 0.9 0.4 25.0 0.3 0.0 0.1 1.0 278.2 0.8 0.7 2.4 1.6 0.0 23.7 0.5 0.1 26.6 1.0 840.8 818.4 3.6 267.1 0.0 0.5 1.3 158.6 0.0 0.5 0.3 0.1 0.0 87.5 0.4 0.7 0.7 54.0 0.2 0.2 0.6 0.0 0.6 0.1 0.8 0.3 0.1 1405.8 37.7 0.4 311.0 19.7 1.0 0.0 0.0 43.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 9.7 0.8 4.1 3.8 26.6 3.4 5.7 7.3 5.6 6.7 9.1 9.1 57.7 5.5 26.1 0.3 15.9 1.5 5.8 4.6 1.2 0.6 1.8 9.7 10.0 39.8 18.4 2.1 0.5 0.1 0.4 0.0 0.3 10.3 1.2 30.6 23.6 1.2 0.0 2.6 0.4 0.4 213.8 9.7 2.4 3.8 0.2 16.1 0.1 0.9 0.0 47.0 0.8 0.0 0.6 23.2 8.8 97.3 1.8 19.6 7.5 0.0 93.7 0.0 1.5 3.3 1.9 5.4 27.8 0.7 1.5 0.2 9.0 5.0 3.7 0.0 106.8 17.5 0.1 0.3 3.9 19.9 0.7 2.1 3.6 1.0 2.9 ABLIM3 KIAA0843 ENSG00000173210 "Actin binding LIM protein family member 3" O94929 5 149141483-149260542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 197.6;Cardiomyocytes: 61.7;Hepatocytes: 116.0;Oligodendrocyte precursor cells: 63.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 75.3;HHSteC: 77.6;HSkMC: 89.4;hTERT-HME1: 90.9;hTERT-RPE1: 76.2;TIME: 103.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003245 Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 30000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Cell Junctions" "HPA003245: AB_1078083" "unprognostic (1.07e-1)" "unprognostic (1.31e-1)" "unprognostic (9.87e-2)" "unprognostic (1.75e-1)" "unprognostic (8.74e-2)" "unprognostic (4.19e-2)" "unprognostic (9.48e-3)" "unprognostic (4.37e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (4.17e-3)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.12e-2)" "unprognostic (8.10e-2)" "unprognostic (2.45e-3)" "unprognostic (1.20e-1)" 68.4 7.4 19.2 3.8 18.0 0.5 57.6 49.7 19.1 12.5 6.8 11.1 2.7 10.4 6.3 33.2 14.4 7.1 87.8 20.4 26.7 19.8 115.8 20.0 5.3 37.2 25.2 3.9 2.7 59.6 6.8 34.4 28.7 9.1 5.0 28.6 6.5 8.2 45.8 8.3 7.8 10.6 34.0 8.7 5.4 2.0 29.9 2.2 9.2 38.7 4.5 14.1 17.7 30.2 23.6 4.8 0.0 0.2 39.6 75.3 0.1 16.1 44.8 9.1 15.8 0.1 16.2 0.0 2.7 20.5 47.9 0.5 0.1 18.9 17.7 0.1 0.2 0.0 1.4 0.6 77.6 0.0 0.1 89.4 5.1 32.5 90.9 76.2 41.1 0.0 0.0 7.2 54.8 9.2 0.0 0.0 0.2 1.5 63.0 0.0 0.1 0.0 50.3 16.0 6.3 0.1 3.3 1.1 8.7 1.2 1.5 0.1 103.9 18.9 4.2 19.9 27.7 0.1 0.0 0.0 33.5 0.0 55.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 2.7 19.2 18.0 49.7 19.1 20.4 26.7 37.2 25.2 28.7 34.0 29.9 30.2 197.6 0.0 3.7 21.5 1.3 1.5 1.2 2.6 0.6 2.5 7.6 3.9 61.7 18.6 5.3 0.0 0.0 0.2 0.3 0.0 5.9 8.7 3.0 0.5 2.5 39.6 0.0 0.0 31.0 3.5 0.7 9.4 3.6 2.5 1.3 0.0 34.2 116.0 12.3 28.6 33.7 0.0 8.2 13.5 1.1 0.5 0.3 8.5 5.4 21.5 0.9 19.3 0.0 63.8 25.6 22.5 0.0 0.7 0.1 2.5 0.0 23.5 4.9 25.1 0.0 7.4 7.7 1.7 2.7 2.0 1.6 0.4 0.7 0.5 0.0 22.2 AC007998.2 ENSG00000267140 "Novel protein" 18 35443871-35497940 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.8" "Cell type enhanced" "Detected in single" "Endothelial cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 63 "HUVEC TERT2: 257.0" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.67e-3)" "unprognostic (5.32e-2)" "unprognostic (2.01e-1)" "unprognostic (3.51e-2)" "unprognostic (1.48e-2)" "unprognostic (2.24e-2)" "unprognostic (1.60e-1)" "unprognostic (7.77e-2)" "unprognostic (4.11e-2)" "unprognostic (1.04e-1)" "unprognostic (2.61e-1)" 1.8 0.2 0.1 1.8 0.2 0.5 3.3 0.1 0.2 2.6 0.2 0.9 0.5 0.8 0.2 0.9 3.2 1.7 0.6 0.2 0.2 0.5 0.1 1.5 4.8 0.2 0.2 0.3 0.5 0.1 0.0 0.5 0.2 0.1 0.8 0.0 0.1 0.7 0.9 0.2 0.6 1.7 0.1 0.8 0.5 0.2 0.2 0.4 1.8 1.4 1.4 1.6 0.1 0.2 0.6 0.4 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.8 0.6 1.1 0.0 0.6 0.7 0.2 0.0 1.3 0.9 0.0 0.2 0.2 1.2 4.1 0.3 2.4 0.5 0.6 1.6 0.0 0.5 0.2 0.3 0.7 257.0 0.0 0.1 0.1 0.0 0.3 0.1 1.1 0.1 0.0 0.0 0.1 0.2 1.6 0.2 0.5 1.1 0.2 0.3 0.7 0.0 0.9 0.0 0.0 0.7 0.6 0.1 0.0 0.8 0.5 0.4 2.0 0.3 1.1 0.2 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.6 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 AC024598.1 ENSG00000285837 "Novel protein" 10 62374192-62672011 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "gallbladder: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.1;TIME: 2.5" HPA052446 Uncertain Approved Vesicles,Centrosome NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Vesicles, Centrosome" "HPA052446: AB_2681836" 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.7 0.0 0.3 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.5 0.3 0.7 0.1 0.4 0.0 0.0 0.1 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC068870.4 ENSG00000288625 "Novel protein" 15 81002142-81002279 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 13 "brain: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "TIME: 8.9" NA NA "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.7 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.1 0.6 0.2 0.3 0.8 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 265.1;testis: 101.9" "Group enriched" "Detected in many" 20 "Early spermatids: 543.6;Late spermatids: 1322.9;Proximal enterocytes: 1172.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC TERT1: 63.3;HUVEC TERT2: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 13.4 4.9 1.7 4.8 8.1 0.1 8.1 0.2 2.5 18.1 0.5 11.2 176.4 8.1 3.5 4.1 6.3 8.2 10.4 1.3 1.0 10.8 1.9 49.0 4.9 1.3 0.9 1.9 6.2 18.7 9.2 11.6 1.3 8.9 6.1 0.4 7.6 23.8 16.1 3.8 265.1 9.6 0.8 2.8 8.3 101.9 2.0 0.8 19.2 10.0 2.1 5.5 3.8 1.1 0.0 0.0 0.0 0.0 2.6 63.3 0.6 2.4 4.7 0.0 0.0 0.9 5.1 1.3 1.8 11.4 0.1 0.0 3.1 0.0 0.0 0.0 1.4 6.6 0.0 0.0 1.4 0.0 0.0 4.2 0.0 0.1 0.0 1.2 33.8 0.0 5.8 0.0 0.1 1.1 0.0 1.4 0.4 11.7 0.7 0.1 0.5 0.9 0.0 0.0 8.2 5.6 0.0 0.0 0.0 1.3 2.9 0.4 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 8.1 0.2 2.5 1.3 1.0 1.3 0.9 1.3 0.8 2.0 1.1 50.0 0.0 3.3 0.0 0.5 1.5 2.6 0.1 1.2 4.0 3.6 1.9 2.1 1.5 0.7 0.0 0.0 0.1 0.3 11.9 0.0 5.9 543.6 10.8 8.0 34.7 18.0 0.0 4.7 0.4 0.1 11.5 2.0 36.3 7.0 24.1 3.6 0.8 4.2 0.0 1.8 39.8 0.0 33.7 3.5 1322.9 4.4 13.6 3.6 4.7 0.0 1.8 0.0 1.0 0.2 0.7 40.9 2.6 0.1 4.2 1172.8 21.7 0.0 1.1 0.0 2.0 4.2 13.5 6.4 0.2 0.1 0.1 2.2 0.3 26.2 2.1 ACER3 "APHC, FLJ11238, PHCA" ENSG00000078124 "Alkaline ceramidase 3" Q9NUN7 11 76860859-77026797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 335.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070087 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA070087: AB_2732147" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "unprognostic (9.54e-3)" "unprognostic (1.37e-1)" "unprognostic (4.06e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (7.13e-2)" "unprognostic (2.35e-3)" "unprognostic (8.45e-3)" "unprognostic (1.30e-1)" "unprognostic (3.68e-3)" "prognostic unfavorable (2.73e-4)" "unprognostic (5.24e-2)" "unprognostic (3.37e-1)" "unprognostic (9.88e-2)" "unprognostic (7.97e-2)" 10.9 3.0 6.2 4.8 8.5 3.0 5.4 8.5 9.3 5.2 4.0 6.4 6.2 4.2 3.1 6.9 4.1 3.2 3.4 6.3 8.5 4.7 2.5 8.0 4.2 8.6 7.1 2.3 2.9 3.5 2.1 6.2 9.5 4.1 5.5 2.3 4.2 2.3 1.6 2.9 4.6 3.9 8.4 5.6 3.4 6.0 7.3 2.2 3.3 1.2 3.8 4.5 4.4 12.0 7.3 7.7 6.4 7.6 29.2 14.0 5.7 11.2 10.7 8.2 9.2 6.0 7.3 6.4 8.4 8.0 10.3 12.9 10.9 10.6 10.0 8.6 4.3 9.0 4.8 3.6 8.1 9.3 15.0 6.3 5.0 11.8 10.9 4.8 16.8 5.8 6.1 4.2 9.9 5.9 0.7 6.2 3.6 19.3 8.8 4.3 22.8 5.0 6.8 7.2 2.2 5.5 13.9 12.6 3.5 4.9 10.7 5.1 22.2 8.2 6.4 23.3 8.3 3.1 7.1 8.6 5.1 4.7 8.9 0.1 4.3 2.5 0.7 3.1 0.8 1.2 0.5 0.9 4.6 0.4 0.3 0.4 0.9 0.2 2.4 1.5 1.2 1.6 6.2 8.5 8.5 9.3 6.3 8.5 8.6 7.1 9.5 8.4 7.3 12.0 32.4 41.7 35.0 52.9 11.5 31.9 21.4 17.0 33.0 18.8 11.3 11.0 7.5 11.5 27.6 9.2 10.4 13.6 11.3 54.6 7.9 15.5 66.8 6.3 29.0 29.4 2.4 13.5 65.0 17.6 7.5 17.0 26.0 11.5 83.5 30.9 27.8 10.0 44.4 43.7 71.9 30.5 18.3 64.1 67.1 31.7 20.2 64.0 17.8 61.8 40.0 11.3 12.3 159.3 335.1 18.6 37.9 25.9 8.6 15.6 20.0 15.3 12.3 10.0 6.6 17.0 21.0 69.8 25.9 26.3 16.8 26.8 15.2 7.2 20.1 24.1 ACTR1A "ARP1, Arp1A" ENSG00000138107 "Actin related protein 1A" P61163 10 102461881-102502712 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037193, HPA047443" Approved Approved Microtubules NA NA 560000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 1: Pancreatic cells - Digestion" Microtubules "CAB037193: AB_258253, HPA047443: AB_2680049" "unprognostic (9.64e-3)" "unprognostic (1.92e-2)" "unprognostic (8.34e-2)" "unprognostic (4.05e-2)" "unprognostic (2.57e-1)" "unprognostic (3.48e-1)" "unprognostic (2.20e-3)" "unprognostic (2.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.01e-1)" "unprognostic (1.66e-2)" "unprognostic (7.77e-2)" "unprognostic (3.41e-2)" "unprognostic (1.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.10e-1)" "unprognostic (4.13e-1)" 59.4 58.8 98.3 39.4 100.6 36.8 51.5 101.9 108.4 50.9 78.4 90.0 37.8 61.8 37.5 61.6 47.4 36.1 93.0 101.9 108.0 49.0 40.4 58.5 33.7 116.3 105.9 36.9 41.9 56.5 54.7 45.3 116.9 53.0 41.7 41.9 46.4 51.9 174.3 65.1 49.1 69.0 97.4 48.7 56.2 40.4 104.0 56.8 41.2 127.0 42.2 74.8 51.2 104.4 80.5 95.8 113.5 117.1 138.0 109.2 45.5 100.3 177.3 154.4 142.4 52.7 63.3 54.4 75.2 149.5 76.2 78.3 109.9 123.7 106.5 70.7 75.8 72.9 53.4 77.9 99.6 56.9 65.0 112.4 89.6 141.2 100.7 155.7 201.6 88.7 60.5 53.5 154.6 67.1 103.5 97.9 45.4 62.5 86.2 78.5 146.0 35.0 125.2 43.9 40.5 88.8 60.1 35.4 75.1 98.3 130.0 38.9 147.0 74.7 71.5 83.6 102.1 54.0 58.8 63.3 78.7 98.3 45.9 32.2 40.7 44.3 31.1 51.8 25.5 18.8 22.0 30.4 40.6 17.6 18.0 20.7 31.2 23.9 57.0 20.8 33.6 39.2 98.3 100.6 101.9 108.4 101.9 108.0 116.3 105.9 116.9 97.4 104.0 104.4 40.0 57.7 41.0 10.1 23.4 33.8 24.0 42.3 13.1 26.6 22.1 17.1 51.6 14.3 34.8 27.6 16.7 54.9 23.8 52.4 54.8 75.5 53.0 15.3 21.0 45.2 39.6 45.9 14.9 77.5 63.3 36.9 23.4 19.3 32.3 27.3 34.6 24.1 73.9 26.9 15.5 24.4 46.8 37.6 38.2 53.9 33.2 44.5 51.6 5.6 70.3 31.5 38.1 10.1 15.3 92.0 36.8 36.1 30.0 26.7 40.9 45.6 26.5 24.5 46.0 17.1 48.5 61.9 14.0 27.3 32.4 104.7 28.2 32.9 24.2 26.6 ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 96.3" "Cell type enhanced" "Detected in many" "Adipocytes: 107.3;Distal enterocytes: 182.7;Endothelial cells: 84.7;Fibroblasts: 56.0;Hepatic stellate cells: 60.3;Paneth cells: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 19 "classical monocyte: 1.5;myeloid DC: 2.1" "Group enriched" "Detected in many" 19 "dendritic cells: 2.1;monocytes: 1.5" "Cell line enhanced" "Detected in some" "ASC diff: 61.4;ASC TERT1: 42.1;EFO-21: 61.0;HUVEC TERT2: 200.0;TIME: 161.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" 49.2 12.1 17.1 20.1 14.5 0.6 38.4 15.5 14.9 35.9 10.5 39.2 10.2 28.1 4.3 11.4 32.7 14.3 38.5 13.3 14.6 29.8 3.3 96.3 15.1 17.8 16.7 4.8 12.0 23.6 6.2 83.8 18.7 17.7 28.4 0.7 11.8 13.3 18.2 18.5 28.5 16.2 14.0 29.2 19.1 1.7 22.0 4.6 29.2 15.7 6.1 25.1 25.6 15.0 0.0 0.7 0.4 0.0 61.4 42.1 0.1 3.0 5.6 0.1 0.3 0.3 0.4 0.1 61.0 24.0 0.2 0.0 0.0 0.0 0.1 0.1 2.1 1.4 0.0 0.0 9.0 0.0 1.3 16.8 0.1 0.4 0.0 0.0 200.0 0.0 0.2 0.1 1.1 0.5 0.0 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 0.1 0.4 0.0 4.1 161.2 0.0 0.4 0.7 0.0 0.0 0.1 0.2 0.3 0.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 17.1 14.5 15.5 14.9 13.3 14.6 17.8 16.7 18.7 14.0 22.0 15.0 107.3 3.2 7.9 0.0 0.6 5.2 0.3 0.0 0.6 0.4 1.0 1.3 4.0 0.0 1.3 0.0 0.0 0.6 0.3 182.7 0.0 4.0 0.0 1.4 19.9 84.7 5.4 0.0 0.1 1.4 36.9 56.0 0.5 0.7 0.0 0.0 60.3 0.1 12.0 0.0 0.0 26.4 0.0 30.9 12.4 1.2 11.8 7.8 5.4 25.3 9.9 2.0 0.0 1.0 0.1 0.0 74.7 3.4 0.1 0.6 4.5 0.0 2.8 0.4 39.5 32.9 18.2 0.1 0.8 0.6 5.4 2.6 1.2 0.6 49.3 1.0 ADAM15 MDC15 ENSG00000143537 "ADAM metallopeptidase domain 15" Q13444 1 155050566-155062775 "Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.5;Extravillous trophoblasts: 172.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 39.1;intermediate monocyte: 26.5;myeloid DC: 64.0" "Group enriched" "Detected in all" 5 "dendritic cells: 64.0;monocytes: 39.1" "Cell line enhanced" "Detected in many" "PC-3: 329.5;RPMI-8226: 361.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011633, HPA072878" Uncertain Uncertain Vesicles NA NA 640000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA011633: AB_1844574, HPA072878: " "unprognostic (6.35e-3)" "unprognostic (1.51e-1)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (5.83e-5)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (2.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.64e-9)" "unprognostic (3.35e-2)" "unprognostic (6.20e-2)" "unprognostic (2.04e-2)" "unprognostic (7.40e-2)" 70.1 18.5 12.5 21.4 16.0 34.1 64.7 16.9 13.9 40.3 7.1 38.3 16.4 42.5 7.6 79.1 41.5 21.6 63.1 10.5 13.8 32.4 15.1 50.0 10.0 20.2 15.1 25.5 25.5 30.0 14.1 39.1 16.8 40.0 23.8 3.4 45.3 16.7 22.7 107.9 31.3 38.6 17.3 28.8 44.2 4.9 17.1 7.3 31.6 32.4 13.6 38.9 57.3 18.0 112.0 35.0 7.0 153.2 54.9 45.6 66.3 48.2 60.9 60.1 40.5 25.9 63.3 30.9 210.7 63.5 26.7 135.9 34.5 147.9 15.8 14.3 44.9 7.6 63.1 25.3 95.5 63.4 7.9 48.7 153.8 60.5 86.6 82.6 274.7 9.3 11.9 124.8 45.2 64.7 0.5 47.1 21.6 193.4 329.5 10.0 20.5 361.8 43.7 29.7 20.8 44.7 105.2 131.2 41.8 10.7 194.8 38.9 205.1 58.6 24.6 58.9 54.1 13.9 11.7 13.7 42.7 47.6 65.4 0.0 39.1 0.8 9.5 26.5 6.5 2.0 4.7 5.6 64.0 2.1 2.0 2.5 1.4 1.6 6.2 5.3 8.9 22.8 12.5 16.0 16.9 13.9 10.5 13.8 20.2 15.1 16.8 17.3 17.1 18.0 164.5 3.2 6.7 8.8 6.6 48.9 30.4 81.6 47.8 9.7 34.6 20.7 11.5 35.8 38.3 9.2 29.2 13.0 8.1 100.4 0.0 33.4 1.7 13.3 9.2 120.8 12.7 4.6 8.1 25.5 172.4 19.8 85.6 15.4 1.3 8.5 62.2 19.9 31.7 6.7 9.8 80.7 18.3 65.0 43.6 1.3 17.4 27.2 14.2 15.9 28.8 8.8 13.4 9.0 16.8 42.1 50.9 18.0 8.0 55.2 47.4 2.6 22.9 17.0 13.1 15.7 14.5 0.8 6.4 91.2 57.1 17.8 8.6 2.7 76.9 40.0 ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184302-161199054 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.8;ovary: 95.9" "Cell type enhanced" "Detected in many" "Adipocytes: 80.3;Endothelial cells: 115.5;Fibroblasts: 88.8;Oligodendrocytes: 56.0;Sertoli cells: 52.6;Smooth muscle cells: 313.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 4.4" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 11.8;HUVEC TERT2: 14.4;SH-SY5Y: 7.9;TIME: 12.2;U-138 MG: 7.4;U-251 MG: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "CAB025876: , HPA051296: AB_2681426, HPA068374: AB_2685978" "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" 116.8 9.8 6.1 16.3 31.5 0.7 43.4 31.1 19.2 16.4 5.8 18.2 0.8 15.0 0.2 6.2 34.6 14.3 53.6 8.1 15.2 26.0 8.7 50.3 1.6 38.2 29.6 95.9 9.0 2.1 13.0 3.2 31.6 16.9 2.0 1.5 5.2 0.5 13.3 5.0 9.4 10.5 28.3 1.8 22.8 1.8 26.2 1.1 21.3 0.4 0.3 31.8 12.2 48.0 0.0 0.0 0.2 0.1 6.4 4.0 0.6 5.4 0.2 0.5 3.0 0.2 0.2 0.2 4.4 1.7 0.0 0.1 0.0 0.0 1.9 0.1 0.3 0.2 0.5 1.3 0.6 0.0 0.1 4.5 0.0 11.8 0.1 0.0 14.4 0.1 0.2 0.3 0.4 0.1 0.0 0.2 5.3 0.0 0.0 0.1 5.1 0.1 0.0 0.1 0.1 7.9 0.0 0.1 0.1 0.3 0.2 0.5 12.2 7.4 0.1 0.4 10.8 0.2 0.1 0.1 2.2 0.1 0.1 0.5 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.0 4.4 0.2 0.1 6.1 31.5 31.1 19.2 8.1 15.2 38.2 29.6 31.6 28.3 26.2 48.0 80.3 0.0 4.1 0.0 0.2 31.2 3.2 0.0 2.2 2.2 8.6 5.5 5.5 0.0 0.6 0.0 0.0 0.3 0.5 0.2 0.0 0.3 0.0 0.3 13.0 115.5 0.0 0.0 0.4 0.0 0.3 88.8 0.5 0.5 0.0 0.3 43.2 0.9 1.0 3.3 0.1 0.0 0.0 1.0 32.6 0.2 0.3 3.2 35.6 2.8 1.0 0.5 0.0 0.0 56.0 0.0 0.0 1.2 0.7 9.8 0.0 0.1 0.0 1.0 52.6 21.2 313.7 2.7 0.6 2.7 19.0 0.4 3.7 1.6 0.3 7.7 ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 13.3" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 2.6" "Region enhanced" "Detected in many" "thalamus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 118.3;HSkMC: 61.2;hTEC/SVTERT24-B: 64.3;hTERT-RPE1: 55.8;LHCN-M2: 64.3;TIME: 207.9;U-138 MG: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" NA NA 28000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (7.77e-2)" "unprognostic (2.01e-4)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (6.41e-2)" "unprognostic (7.29e-3)" "unprognostic (2.58e-2)" "unprognostic (1.87e-1)" "unprognostic (6.59e-2)" "unprognostic (1.50e-2)" 3.9 5.5 1.0 1.9 0.9 0.0 2.4 1.7 1.1 3.8 0.0 3.0 1.8 13.3 1.1 5.4 4.0 4.9 1.0 3.6 1.8 2.1 0.9 1.2 0.8 2.1 3.3 1.5 1.4 0.2 1.8 0.6 0.5 8.1 2.9 0.4 1.3 1.6 0.4 0.9 1.8 11.2 1.4 0.7 5.1 1.0 9.6 0.5 0.9 0.8 0.9 2.6 2.0 1.0 6.4 0.5 1.2 0.0 17.5 118.3 0.0 3.6 16.3 14.8 33.3 0.0 0.1 0.1 0.1 44.1 5.5 0.0 6.6 1.1 41.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 61.2 0.0 64.3 0.2 55.8 27.1 0.0 0.1 0.3 64.3 0.0 0.2 0.1 5.6 0.0 0.3 0.0 10.1 0.2 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 207.9 96.9 2.5 2.6 15.8 0.0 0.0 0.0 31.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.7 1.1 3.6 1.8 2.1 3.3 0.5 1.4 9.6 1.0 1.6 0.0 0.0 5.2 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.4 1.4 0.0 0.6 0.0 0.0 0.0 0.0 3.1 0.0 0.1 7.2 0.3 1.1 8.9 0.0 0.0 245.4 0.0 0.0 15.1 0.5 0.5 0.0 0.1 1.1 0.0 0.1 0.0 39.5 0.4 0.0 0.0 0.8 2.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 9.0 5.7 0.0 0.4 1.2 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.1 1.2 2.9 1.6 0.1 0.1 0.1 0.0 0.1 1.7 0.1 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 428.1;Alveolar cells type 1: 291.7;Alveolar cells type 2: 539.9;Endothelial cells: 222.6;Hepatic stellate cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 25.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" 69.8 22.8 15.1 6.9 15.0 0.0 46.0 15.0 18.0 10.4 8.6 9.9 5.7 16.0 7.7 7.0 15.0 16.9 51.6 12.8 15.1 58.9 13.0 104.5 8.5 16.6 15.6 6.5 6.4 13.2 6.7 50.6 18.2 8.9 5.7 1.8 5.9 9.2 30.4 7.7 8.5 21.8 13.8 40.5 8.4 3.1 21.6 3.7 32.2 70.2 3.2 11.4 10.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 74.1 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 15.0 18.0 12.8 15.1 16.6 15.6 18.2 13.8 21.6 15.3 428.1 291.7 539.9 2.0 2.9 0.0 0.2 0.0 2.2 0.0 1.5 2.9 16.2 8.6 89.7 1.8 0.0 0.2 1.1 0.6 11.7 0.2 10.6 0.8 1.2 222.6 0.0 0.0 8.4 0.0 1.1 9.0 2.6 0.4 12.6 0.0 251.3 4.0 0.2 0.0 1.0 0.5 0.0 13.7 0.0 4.8 3.1 2.7 0.0 104.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.6 0.5 0.2 48.1 0.7 98.6 9.6 80.1 0.2 0.9 0.6 0.0 0.3 1.8 15.5 0.1 0.8 ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 216.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 222.5;Exocrine glandular cells: 170.7;NK-cells: 208.1;Syncytiotrophoblasts: 186.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.3" "Lineage enriched" "Detected in many" 5 "T-cells: 160.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 218.4;SK-BR-3: 277.7;SK-MEL-30: 297.8;TIME: 241.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" NA NA 32000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" 50.9 13.2 79.6 12.7 67.7 19.6 50.5 46.9 115.2 36.3 0.0 36.7 26.1 19.7 84.2 46.7 52.2 69.6 36.8 68.7 71.5 158.9 4.2 37.3 5.2 64.6 76.2 5.3 59.8 28.4 17.7 101.3 73.9 31.7 33.4 6.6 92.2 57.5 15.7 87.5 19.3 19.8 54.8 12.3 47.9 45.4 92.5 28.9 216.3 16.9 15.6 37.1 37.8 51.6 41.8 47.1 12.0 0.6 0.0 0.1 127.7 8.5 3.9 14.4 2.6 34.7 218.4 0.2 110.5 8.2 196.1 149.1 0.0 103.4 5.1 1.6 0.0 5.1 56.0 39.3 0.3 0.4 2.1 2.4 143.8 24.5 10.2 15.8 118.1 1.0 0.1 1.2 3.2 51.4 107.3 0.8 1.7 143.3 42.6 3.8 1.4 30.8 209.4 134.9 38.2 1.2 2.0 277.7 297.8 8.4 123.8 0.8 241.4 25.6 38.0 1.5 96.2 0.2 2.1 0.6 200.5 0.7 62.9 2.9 0.8 0.2 160.3 0.5 1.9 0.3 10.5 62.6 0.2 0.1 5.3 45.2 3.3 30.6 0.7 0.3 0.2 37.1 79.6 67.7 46.9 115.2 68.7 71.5 64.6 76.2 73.9 54.8 92.5 51.6 107.7 9.6 11.9 113.9 3.7 0.0 24.1 0.0 11.4 0.9 29.6 27.2 4.3 15.7 21.7 79.1 0.0 222.5 120.4 17.7 27.4 33.9 74.0 24.6 4.3 53.9 20.6 17.7 3.5 170.7 25.1 4.7 29.0 45.2 5.1 88.2 30.0 0.5 22.8 0.0 4.9 23.2 0.0 3.5 0.0 31.3 3.1 6.1 0.0 41.2 1.1 4.8 208.1 85.5 1.3 101.1 12.3 0.0 19.1 15.2 5.6 132.6 16.8 0.5 0.0 1.6 7.1 2.7 0.9 23.0 0.0 186.5 35.1 0.4 24.6 19.5 ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 73.1" "Group enriched" "Detected in many" 5 "Adipocytes: 559.9;Endothelial cells: 276.0;Hepatic stellate cells: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 101.2;HUVEC TERT2: 330.0;TIME: 379.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" 73.1 8.2 7.7 9.7 8.2 0.7 64.0 8.5 13.8 22.1 7.0 9.3 4.7 16.3 6.2 9.0 12.1 22.4 24.2 8.0 8.0 15.2 14.3 18.0 9.9 9.1 7.7 4.8 4.7 9.7 5.1 22.5 9.1 9.4 6.3 3.0 7.9 8.9 14.2 9.0 8.6 27.6 7.6 39.8 8.0 6.7 9.8 4.6 20.8 23.6 7.1 24.0 10.4 8.4 0.0 0.0 25.7 0.2 7.3 24.7 0.0 7.8 7.7 0.5 0.3 0.8 0.2 0.2 0.6 22.5 0.0 0.0 0.1 0.0 5.0 0.0 0.0 0.5 0.7 0.1 25.3 0.0 0.3 17.8 0.4 55.7 0.3 101.2 330.0 0.2 0.4 2.5 7.0 0.0 0.0 1.0 0.4 0.2 0.4 0.2 0.0 0.0 61.1 3.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 379.3 0.2 5.8 2.0 0.0 0.8 0.5 0.1 0.3 0.5 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.7 8.2 8.5 13.8 8.0 8.0 9.1 7.7 9.1 7.6 9.8 8.4 559.9 0.0 6.0 0.3 1.2 0.0 0.4 0.0 4.6 0.0 1.8 2.5 7.6 5.7 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 45.3 0.8 1.5 276.0 0.0 2.7 1.5 0.2 0.0 10.2 0.0 3.8 0.0 0.0 287.7 3.5 0.6 1.7 1.0 0.0 0.0 19.2 0.0 57.9 0.6 1.5 0.0 72.1 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.4 1.2 1.3 0.0 0.0 0.0 0.4 0.0 5.1 5.7 7.2 1.8 1.0 0.0 0.0 1.1 5.4 0.0 0.7 ADSS2 ADSS ENSG00000035687 "Adenylosuccinate synthase 2" P30520 1 244408494-244451909 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 26.4;Cytotrophoblasts: 49.3;dendritic cells: 59.6;Extravillous trophoblasts: 97.2;Hofbauer cells: 35.8;Syncytiotrophoblasts: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024400 Supported Approved "Plasma membrane,Cytosol" NA NA 690000 "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA024400: AB_1844623" "unprognostic (4.24e-3)" "unprognostic (2.63e-1)" "unprognostic (3.95e-2)" "unprognostic (8.68e-2)" "unprognostic (6.91e-2)" "unprognostic (2.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (1.01e-2)" "unprognostic (1.44e-2)" "unprognostic (3.10e-1)" "unprognostic (1.35e-1)" "unprognostic (7.62e-2)" "unprognostic (1.86e-1)" "unprognostic (2.04e-1)" "unprognostic (1.18e-2)" 19.8 20.5 17.8 28.1 22.0 43.9 34.6 21.7 26.7 25.9 17.0 28.7 28.7 23.4 29.8 32.6 23.9 21.0 8.9 19.2 21.1 32.9 24.3 25.3 31.9 21.9 19.6 21.7 19.8 27.6 14.5 28.6 23.1 25.3 29.8 11.4 22.8 25.6 10.8 33.2 27.1 25.2 19.6 23.7 35.0 70.3 20.9 33.8 34.9 8.4 34.9 36.2 21.5 28.7 89.9 48.6 41.6 36.9 47.6 67.8 76.2 88.5 74.4 62.3 47.0 64.6 84.5 79.7 57.1 68.9 26.6 66.1 45.9 58.0 69.5 59.6 81.0 53.1 47.8 49.3 57.1 127.1 65.6 46.8 68.5 58.1 58.3 72.1 225.6 43.3 94.0 57.7 62.7 21.6 82.3 85.0 110.5 85.0 53.1 74.9 39.4 86.5 103.8 55.2 56.2 49.2 75.2 69.0 91.4 43.9 48.0 66.7 99.4 57.1 31.3 67.0 93.7 69.1 97.2 60.0 47.2 146.8 86.3 48.3 22.8 20.0 20.4 29.9 22.0 15.3 18.6 17.8 20.1 12.3 15.6 17.9 17.5 23.6 33.6 7.9 22.3 18.8 17.8 22.0 21.7 26.7 19.2 21.1 21.9 19.6 23.1 19.6 20.9 28.7 26.4 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 49.3 59.6 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 97.2 9.3 0.0 0.0 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 54.0 11.0 0.0 0.0 0.0 ADTRP "AIG1L, C6orf105, dJ413H6.1" ENSG00000111863 "Androgen dependent TFPI regulating protein" Q96IZ2 6 11712054-11807046 "Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 98.5;parathyroid gland: 92.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 116.4;Distal tubular cells: 52.8;Early spermatids: 141.6;Late spermatids: 168.0;Paneth cells: 87.0;Proximal enterocytes: 127.0;Undifferentiated cells: 52.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 14.8;T-reg: 13.5" "Lineage enriched" "Detected in many" 5 "T-cells: 14.8" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 93.9;RPMI-8226: 41.2;TIME: 57.7;U-138 MG: 42.4;U-266/84: 47.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA048113 Uncertain Uncertain Nucleoli NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoli "HPA048113: AB_2680268" "unprognostic (6.82e-3)" "unprognostic (1.41e-1)" "unprognostic (1.58e-1)" "unprognostic (8.14e-3)" "unprognostic (3.04e-3)" "unprognostic (1.41e-2)" "unprognostic (4.00e-2)" "unprognostic (1.77e-1)" "unprognostic (1.85e-2)" "unprognostic (2.72e-1)" "unprognostic (5.41e-3)" "unprognostic (2.90e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (2.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.95e-2)" "unprognostic (1.26e-1)" 0.5 0.2 1.9 14.2 2.1 1.1 3.3 0.6 2.2 0.4 35.2 80.7 82.4 0.3 13.7 1.5 0.6 1.6 0.3 2.0 0.0 9.8 1.4 11.1 9.4 0.1 0.1 0.2 0.8 92.9 0.0 2.4 0.1 0.4 58.5 0.6 0.8 24.4 1.0 18.9 98.5 2.6 0.1 1.3 38.2 22.6 0.4 2.6 0.5 0.1 12.7 10.2 0.3 1.1 4.1 0.0 0.0 0.0 0.5 0.9 0.1 1.5 0.8 1.0 0.7 3.6 1.9 0.1 1.7 0.7 2.4 1.9 0.0 11.2 1.4 0.1 0.0 0.3 0.8 0.1 0.3 0.1 0.2 0.0 20.4 10.4 23.6 17.5 93.9 0.7 23.0 0.0 3.1 0.1 0.2 0.6 0.3 0.1 5.8 0.0 0.3 41.2 1.7 0.2 0.1 0.2 1.5 0.0 0.8 2.8 0.0 0.8 57.7 42.4 2.0 0.7 2.6 1.2 47.1 0.0 7.9 1.3 0.2 2.7 0.0 0.0 0.0 0.3 2.6 0.2 3.7 0.3 0.1 0.2 14.8 1.3 0.3 0.1 0.2 0.2 13.5 1.7 1.9 2.1 0.6 2.2 2.0 0.0 0.1 0.1 0.1 0.1 0.4 1.1 0.2 0.0 1.1 0.7 4.0 5.1 0.3 3.9 0.6 0.0 0.1 1.9 0.1 0.0 2.6 5.5 0.0 0.2 0.1 116.4 52.8 0.7 141.6 0.2 0.0 0.3 5.4 2.7 13.1 2.4 0.2 1.1 32.1 0.1 5.7 0.0 0.0 0.2 11.4 0.0 0.4 40.7 2.0 0.8 1.5 168.0 1.8 3.1 1.8 0.0 27.9 0.0 1.0 1.0 0.1 7.9 87.0 0.7 7.8 0.6 127.0 0.7 0.8 0.0 0.0 0.2 1.2 1.6 0.7 0.4 5.7 0.1 6.2 0.0 52.3 0.5 AHNAK MGC5395 ENSG00000124942 "AHNAK nucleoprotein" Q09666 11 62433542-62556235 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 561.4;fHDF/TERT166: 554.5;TIME: 582.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 395.4" "HPA019010, HPA019070, HPA026643" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA 10000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA019010: AB_1844657, HPA019070: AB_1844656, HPA026643: AB_10670426" "unprognostic (1.39e-1)" "unprognostic (7.84e-2)" "unprognostic (3.46e-1)" "unprognostic (3.19e-1)" "unprognostic (1.96e-2)" "unprognostic (5.99e-2)" "unprognostic (2.53e-1)" "unprognostic (1.63e-2)" "unprognostic (4.84e-2)" "unprognostic (1.98e-3)" "prognostic unfavorable (2.42e-4)" "unprognostic (4.30e-1)" "unprognostic (4.49e-3)" "unprognostic (5.42e-2)" "unprognostic (1.18e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.47e-6)" 243.1 27.9 62.6 43.4 50.2 44.1 190.3 33.7 45.4 183.3 61.0 276.2 49.0 183.3 51.7 248.2 145.5 74.8 115.1 65.0 98.0 59.7 60.1 144.1 36.7 76.2 48.3 125.8 30.3 26.3 16.9 97.3 62.9 88.5 96.6 10.1 127.5 105.7 188.5 334.7 136.6 113.1 60.8 59.5 133.5 18.0 49.0 27.9 64.9 172.2 63.7 142.0 213.3 78.4 188.2 107.9 9.8 44.1 421.8 561.4 70.3 166.0 201.4 103.0 57.4 93.7 64.9 0.2 61.7 554.5 79.8 244.1 41.2 203.7 130.7 154.2 7.3 22.6 173.4 27.9 80.8 31.5 142.2 204.2 233.0 202.4 183.6 131.5 215.4 2.7 21.8 138.8 211.7 72.1 0.4 60.7 3.0 59.6 171.7 0.4 45.1 113.9 227.1 120.2 0.3 9.2 167.5 69.3 69.0 198.8 133.7 28.4 582.1 182.4 119.8 229.8 74.4 25.0 5.4 0.6 138.2 10.1 60.9 44.1 75.6 0.3 38.7 45.0 25.8 20.0 24.8 31.7 73.8 16.1 3.2 17.3 1.1 31.5 37.8 20.2 21.5 36.8 62.6 50.2 33.7 45.4 65.0 98.0 76.2 48.3 62.9 60.8 49.0 78.4 413.1 439.1 106.3 49.3 171.4 479.4 133.8 285.0 253.2 1.4 173.0 226.8 199.9 195.9 224.1 193.1 0.0 110.8 194.3 400.8 13.7 99.6 10.6 188.5 195.0 282.5 47.6 43.7 0.9 64.1 145.6 312.9 538.2 351.2 238.9 4.3 201.4 88.5 79.4 1.7 0.8 164.8 138.4 329.8 458.3 33.2 451.4 292.3 318.4 43.1 284.8 30.7 138.0 0.5 0.4 262.5 195.5 466.0 329.0 202.4 262.3 6.8 149.3 1.2 177.5 349.5 244.4 3.1 8.1 596.4 610.3 102.2 256.5 3.0 101.8 198.0 AKAP12 "AKAP250, SSeCKS" ENSG00000131016 "A-kinase anchoring protein 12" Q02952 6 151239967-151358559 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 352.6;Endothelial cells: 278.4;Fibroblasts: 270.0;Muller glia cells: 583.0;Pancreatic endocrine cells: 322.1;Spermatocytes: 325.4" "Cancer enhanced" "Detected in all" "testis cancer: 39.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 235 "basophil: 37.2" "Lineage enriched" "Detected in single" 235 "granulocytes: 37.2" "Cell line enhanced" "Detected in many" "REH: 193.0;TIME: 188.2;U-251 MG: 202.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006344, CAB026379, HPA056230" Enhanced Enhanced "Plasma membrane,Cytosol" No No 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB026379: , HPA006344: AB_1078118, HPA056230: AB_2683073" "unprognostic (6.66e-2)" "unprognostic (1.51e-1)" "unprognostic (9.90e-3)" "prognostic unfavorable (7.08e-4)" "unprognostic (2.61e-2)" "unprognostic (8.88e-2)" "unprognostic (5.05e-2)" "prognostic unfavorable (6.34e-5)" "unprognostic (1.34e-1)" "unprognostic (8.26e-3)" "unprognostic (2.59e-1)" "unprognostic (4.72e-2)" "unprognostic (4.51e-3)" "unprognostic (1.10e-3)" "unprognostic (3.51e-1)" "unprognostic (7.03e-3)" "unprognostic (2.34e-2)" 105.6 16.0 13.8 17.1 16.6 2.2 59.7 99.7 57.5 19.8 4.5 60.1 8.6 31.1 9.3 18.6 31.2 31.5 51.8 14.7 66.8 35.8 30.6 44.3 6.9 67.0 35.3 87.8 10.8 1.6 23.3 38.3 74.7 23.1 13.2 109.4 6.5 20.8 11.9 9.4 24.9 42.9 10.9 14.3 25.6 100.0 39.4 5.9 22.1 14.5 3.4 33.0 21.2 24.3 7.8 37.8 53.2 0.1 98.2 145.9 18.8 43.9 23.7 19.3 19.4 0.9 141.6 0.0 17.1 33.2 160.4 1.0 102.2 32.5 17.2 50.2 37.6 0.6 40.8 35.6 10.9 0.0 9.6 104.0 0.0 81.9 4.3 25.4 127.8 0.6 9.8 0.9 70.7 0.5 0.3 0.1 33.3 0.1 43.9 193.0 2.3 0.2 110.2 6.3 37.9 22.0 14.1 0.5 24.9 74.6 2.8 0.5 188.2 2.6 34.0 110.4 202.9 0.4 0.1 0.2 63.2 0.1 37.4 37.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 16.6 99.7 57.5 14.7 66.8 67.0 35.3 74.7 10.9 39.4 24.3 352.6 12.8 16.2 34.3 6.8 19.6 19.6 63.2 1.2 14.5 1.2 3.9 12.1 5.7 31.1 51.5 2.1 2.4 0.9 1.2 1.9 107.0 101.4 14.2 195.4 278.4 1.8 3.2 75.8 6.7 10.1 270.0 3.6 31.6 64.2 14.7 194.5 4.8 26.9 0.0 33.3 0.7 4.1 15.7 45.4 116.3 39.7 13.9 58.7 37.5 0.6 583.0 1.0 59.8 5.1 322.1 1.1 110.6 6.7 49.5 0.0 89.4 6.0 31.0 98.6 208.3 243.0 325.4 33.0 1.6 11.4 10.0 5.1 9.3 2.5 105.3 AKTIP "FLJ13258, FTS" ENSG00000166971 "AKT interacting protein" Q9H8T0 16 53491040-53504411 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 168.3;Late spermatids: 325.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041794, HPA046300" Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 54: Non-specific - Microtubule organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "HPA041794: AB_2677677, HPA046300: AB_2679619" "unprognostic (2.08e-2)" "unprognostic (5.92e-2)" "unprognostic (2.50e-2)" "unprognostic (5.44e-2)" "unprognostic (2.62e-2)" "unprognostic (9.90e-2)" "unprognostic (1.72e-2)" "unprognostic (3.41e-3)" "unprognostic (2.45e-1)" "unprognostic (2.60e-2)" "unprognostic (1.50e-3)" "unprognostic (7.66e-2)" "prognostic favorable (1.18e-14)" "unprognostic (2.39e-3)" "unprognostic (1.86e-1)" "unprognostic (2.67e-1)" "unprognostic (1.31e-1)" 29.3 20.5 46.9 15.7 48.9 32.1 24.7 47.8 55.7 24.5 42.0 30.2 15.5 22.3 31.6 33.2 21.4 17.4 55.3 50.9 47.2 37.1 31.8 24.4 22.5 51.5 46.9 30.4 17.3 44.9 29.0 30.2 52.8 24.7 17.8 76.9 20.5 31.0 134.9 26.9 20.0 25.7 47.6 15.5 21.2 44.0 47.5 13.2 31.7 81.4 24.2 25.1 26.1 48.9 40.2 25.7 17.2 22.7 22.8 17.2 50.5 24.7 18.6 21.5 5.3 35.0 20.6 6.6 14.9 25.4 16.2 34.0 14.9 20.0 28.8 9.7 23.6 1.9 13.6 28.1 29.6 9.2 17.1 14.6 55.1 21.4 18.4 31.2 37.1 13.4 3.6 14.1 19.2 31.2 8.0 13.7 11.9 19.2 24.6 9.6 28.5 30.3 28.4 33.2 13.5 16.8 14.9 52.4 22.4 22.9 46.7 5.7 35.2 23.1 25.1 15.2 24.4 20.6 19.6 13.5 24.9 8.1 15.0 22.3 4.5 11.0 32.4 3.4 19.5 9.1 31.1 33.9 2.0 13.7 47.7 39.3 29.3 27.1 3.4 3.0 46.4 19.1 46.9 48.9 47.8 55.7 50.9 47.2 51.5 46.9 52.8 47.6 47.5 48.9 41.9 25.6 15.4 11.8 9.3 7.0 15.1 29.0 5.7 28.4 17.9 11.9 32.2 17.2 25.4 23.9 16.7 80.3 13.6 15.0 82.2 29.8 168.3 11.2 7.1 22.2 6.0 3.6 19.4 20.5 44.3 16.4 8.2 12.9 3.8 9.6 26.0 26.3 13.3 21.9 20.2 6.5 44.7 7.0 5.6 325.9 14.0 6.2 23.2 7.5 8.0 58.8 28.8 8.5 21.5 20.6 6.0 38.4 12.2 15.0 36.2 38.2 22.0 27.3 6.6 22.1 22.2 16.1 40.4 11.2 12.8 77.3 28.7 8.4 11.5 19.0 AL049629.2 ENSG00000284969 "Novel protein" 11 33698261-33722467 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Ductal cells: 9.1;Exocrine glandular cells: 14.4;Pancreatic endocrine cells: 44.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 42.8;HUVEC TERT2: 55.1;TIME: 66.2;U-2197: 57.6" HPA026494 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Vesicles" "HPA026494: AB_1846321" 2.5 0.7 1.5 2.3 1.4 1.5 1.1 1.5 1.6 0.5 2.5 0.7 1.4 1.3 1.8 1.2 0.6 2.1 1.1 1.4 1.7 1.6 0.8 1.7 0.3 1.8 2.0 0.6 0.7 1.0 1.5 1.8 0.5 0.7 0.6 2.4 0.7 3.5 0.3 0.3 0.6 1.8 0.5 2.9 1.1 1.8 0.2 0.8 1.1 1.4 2.3 2.1 1.3 3.3 0.2 2.4 3.4 7.9 0.1 18.5 8.4 2.3 2.2 0.1 9.6 0.0 2.3 12.5 1.1 2.2 0.3 42.8 4.0 2.0 0.4 0.3 7.1 0.8 0.8 0.4 1.2 3.0 2.7 1.0 14.7 1.9 55.1 0.3 0.5 7.4 15.4 1.0 1.8 0.8 0.5 1.3 24.8 0.4 1.5 1.3 4.9 2.2 0.0 0.3 2.0 3.4 7.3 0.2 1.0 0.0 66.2 7.0 2.7 57.6 7.4 3.8 3.7 0.3 16.0 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.5 1.4 1.5 1.6 1.4 1.7 1.8 2.0 1.8 1.8 1.8 2.1 0.5 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.7 0.2 2.1 0.0 0.0 0.0 14.4 0.0 0.2 0.0 1.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 AL353579.1 ENSG00000286105 "Transmembrane protein 217" 6 37212181-37257637 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "testis: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;HBF TERT88: 1.2;HEL: 1.2;hTEC/SVTERT24-B: 1.2;TIME: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" 0.1 0.0 0.2 0.0 0.2 0.6 0.0 0.1 0.7 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.1 0.0 0.2 0.2 0.0 0.3 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 4.6 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.5 1.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.2 0.0 1.2 0.8 0.1 0.4 0.0 0.4 0.5 0.0 1.2 0.0 0.0 0.6 0.0 0.3 0.0 0.1 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.7 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AMN1 ENSG00000151743 "Antagonist of mitotic exit network 1 homolog" Q8IY45 12 31671142-31729121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 56.7" "Cell type enhanced" "Detected in many" "Early spermatids: 384.0;Late spermatids: 156.1;Spermatocytes: 232.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 51.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046157, HPA062290" Approved Approved Centrosome NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Centrosome "HPA046157: AB_10965846, HPA062290: AB_2684739" "unprognostic (2.11e-2)" "unprognostic (2.52e-1)" "unprognostic (3.36e-1)" "unprognostic (2.60e-1)" "unprognostic (2.80e-1)" "unprognostic (5.93e-2)" "unprognostic (8.60e-3)" "unprognostic (4.08e-2)" "unprognostic (6.48e-2)" "unprognostic (3.01e-2)" "unprognostic (1.39e-1)" "unprognostic (7.28e-2)" "unprognostic (2.48e-1)" "unprognostic (4.74e-2)" "unprognostic (1.38e-1)" "unprognostic (1.25e-1)" "unprognostic (1.30e-1)" 6.2 10.8 28.1 6.9 29.1 3.4 9.6 25.2 36.4 9.8 18.1 6.0 4.0 11.6 8.4 6.2 18.7 7.5 11.7 30.5 26.9 12.0 6.2 6.9 12.8 25.1 25.1 17.2 8.7 13.7 12.5 5.6 24.8 9.3 4.3 46.0 6.8 7.7 18.4 6.2 6.0 7.5 25.7 10.2 9.4 56.7 26.5 19.5 8.5 20.0 10.2 8.9 6.8 33.1 5.4 11.6 8.5 0.7 8.5 10.8 5.2 5.7 8.2 3.7 7.1 6.0 19.8 2.6 11.9 4.8 28.1 2.8 4.3 6.4 7.6 4.6 5.4 9.7 3.9 8.7 15.4 5.0 4.8 7.1 10.5 6.3 8.9 28.4 21.4 13.9 8.4 8.0 14.3 3.3 2.9 4.0 12.5 11.2 5.1 4.2 14.7 4.5 8.7 11.9 14.7 11.2 7.3 1.5 11.7 19.3 16.9 5.6 11.5 6.1 5.1 5.2 9.9 9.1 9.5 9.0 8.2 4.5 11.9 8.2 5.0 6.4 7.4 3.7 7.5 22.1 7.7 7.9 4.0 19.3 16.9 10.5 51.8 9.4 3.2 12.4 12.8 5.9 28.1 29.1 25.2 36.4 30.5 26.9 25.1 25.1 24.8 25.7 26.5 33.1 13.2 6.4 2.7 25.5 25.7 9.3 25.6 35.3 12.5 11.7 10.5 6.7 4.0 7.2 22.3 16.5 27.1 7.1 3.1 2.1 27.4 10.5 384.0 20.0 4.7 11.5 14.4 1.7 48.6 7.2 5.3 7.7 7.1 12.1 7.6 8.1 11.4 3.2 9.0 30.3 58.5 1.9 42.7 6.0 6.8 156.1 10.2 7.7 16.0 13.1 4.1 15.9 11.3 22.1 67.3 11.1 1.0 13.5 5.4 16.9 2.0 11.4 22.9 43.2 0.0 6.1 11.2 232.9 31.1 6.9 12.6 7.3 9.5 10.8 2.1 32.3 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANGPTL4 "ARP4, FIAF, HFARP, NL2, PGAR, pp1158" ENSG00000167772 "Angiopoietin like 4" Q9BY76 19 8363289-8374370 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 195.8;breast: 165.0;liver: 183.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 318.9;Hepatocytes: 148.4;Pancreatic endocrine cells: 230.4;Proximal enterocytes: 146.3;Skeletal myocytes: 198.3" "Cancer enriched" "Detected in all" 4 "renal cancer: 212.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 3.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "ASC diff: 54.6;HBEC3-KT: 226.5;LHCN-M2: 60.9;TIME: 114.6;U-138 MG: 65.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA007879, CAB033770" Approved Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 7750000 3100000 "Cluster 41: Basophils - Cellular respiration" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "CAB033770: AB_2057427, HPA007879: AB_1078158" "unprognostic (1.26e-1)" "unprognostic (5.29e-3)" "prognostic unfavorable (7.53e-4)" "unprognostic (1.88e-2)" "unprognostic (7.68e-3)" "unprognostic (3.58e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (9.50e-4)" "unprognostic (3.18e-1)" "unprognostic (3.90e-3)" "unprognostic (9.69e-3)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.34e-5)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.00e-2)" 195.8 23.0 25.2 15.4 31.8 1.4 165.0 26.2 32.6 18.8 14.0 25.6 11.5 6.8 0.1 41.2 7.9 9.4 45.4 27.7 27.0 51.9 183.7 46.6 2.0 30.1 37.6 9.1 70.8 1.0 16.1 18.3 27.2 30.4 0.9 3.2 19.1 2.6 24.8 30.2 28.0 6.0 27.3 13.1 21.7 6.7 33.8 0.7 34.1 6.2 2.8 26.6 32.1 33.7 0.1 2.2 1.2 3.3 54.6 12.0 0.7 4.4 0.5 0.7 0.2 0.0 20.9 0.2 30.6 8.8 4.5 3.0 0.0 226.5 0.4 1.9 0.4 0.3 0.9 0.9 1.2 0.1 0.2 5.6 1.0 34.0 0.7 6.2 17.4 0.6 1.1 0.5 60.9 1.8 0.2 2.1 0.3 0.0 1.8 1.3 0.1 1.0 11.1 4.0 0.2 0.5 26.2 2.7 4.3 1.5 6.8 0.4 114.6 65.1 0.3 33.3 0.0 0.3 0.1 0.2 44.9 0.0 12.4 3.3 0.1 0.4 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.9 0.3 0.0 0.1 0.2 0.1 25.2 31.8 26.2 32.6 27.7 27.0 30.1 37.6 27.2 27.3 33.8 33.7 53.5 38.5 5.8 128.0 1.2 14.0 39.8 318.9 17.1 0.2 71.8 49.0 5.3 1.5 85.7 14.7 0.0 7.4 2.5 17.1 0.0 107.1 0.7 4.2 6.9 28.9 0.0 0.0 0.4 18.0 111.2 89.1 46.9 13.8 2.5 1.5 17.9 148.4 8.3 0.0 0.6 14.2 16.2 1.6 10.3 2.2 88.0 5.0 8.8 2.8 2.0 2.7 0.0 1.0 4.5 230.4 8.4 131.7 1.0 38.3 146.3 4.5 19.0 0.1 32.9 198.3 121.5 0.0 3.1 21.8 11.5 40.1 2.3 20.7 6.7 77.7 ANKRD1 "ALRP, C-193, CARP, CVARP, MCARP" ENSG00000148677 "Ankyrin repeat domain 1" Q15327 10 90912096-90921087 "Metabolic proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "heart muscle: 6540.8" "Cell type enriched" "Detected in some" 15 "Cardiomyocytes: 13820.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 474.5;EFO-21: 1248.9;hTERT-RPE1: 679.8;LHCN-M2: 1573.6;SuSa: 469.1;TIME: 2206.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA038736 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoli fibrillar center" Nucleoplasm "HPA038736: AB_2676184" "unprognostic (2.45e-1)" "unprognostic (6.14e-3)" "unprognostic (2.24e-1)" "unprognostic (4.39e-1)" "unprognostic (9.14e-3)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.28e-2)" "unprognostic (6.63e-3)" "unprognostic (2.19e-1)" "unprognostic (3.27e-1)" "unprognostic (4.51e-2)" "unprognostic (3.40e-1)" "unprognostic (2.72e-5)" "unprognostic (3.40e-2)" "unprognostic (2.79e-1)" "unprognostic (7.22e-2)" "unprognostic (3.16e-3)" 0.9 0.7 0.0 0.4 0.0 0.0 1.8 0.2 0.3 0.6 0.6 0.7 0.0 0.4 0.0 0.6 0.1 1.3 6540.8 0.0 0.2 0.7 1.6 48.6 2.5 0.0 0.2 0.7 4.8 0.2 1.1 4.2 0.0 6.8 0.0 0.0 8.7 0.1 571.0 2.3 0.6 2.1 0.0 0.5 1.0 0.9 0.8 1.5 1.7 20.5 0.0 1.2 0.5 0.1 37.2 10.8 6.6 0.3 5.8 6.7 0.5 21.5 2.2 6.0 10.8 474.5 17.9 0.3 1248.9 1.8 48.5 13.3 2.3 3.1 15.7 1.4 1.2 0.2 2.9 148.5 27.7 0.0 0.0 44.2 0.1 9.5 21.6 679.8 437.8 0.0 0.3 0.0 1573.6 0.4 0.0 0.0 1.3 2.7 0.3 0.0 104.3 0.0 3.9 0.5 0.1 0.0 0.3 0.4 1.2 469.1 0.3 1.9 2206.7 4.1 163.9 3.2 175.0 0.0 1.2 3.0 0.9 0.6 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.1 0.0 913.5 42.0 0.0 0.0 0.0 3.5 18.5 0.0 0.0 0.0 0.0 13820.4 7.2 6.6 0.0 0.0 0.6 0.0 0.0 0.0 66.3 5.7 9.4 0.2 83.6 0.0 0.0 0.0 0.2 0.2 243.5 0.0 4.6 3.8 1.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.4 0.0 0.1 1.0 0.0 0.0 74.5 100.9 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.1 ANKRD50 KIAA1223 ENSG00000151458 "Ankyrin repeat domain 50" Q9ULJ7 4 124664048-124712732 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-HME1: 56.8;HUVEC TERT2: 58.2;TIME: 147.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044008 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA044008: AB_10961996" "unprognostic (7.82e-2)" "unprognostic (1.68e-2)" "unprognostic (6.85e-3)" "unprognostic (5.90e-1)" "unprognostic (9.77e-2)" "unprognostic (1.19e-1)" "unprognostic (2.72e-1)" "unprognostic (7.26e-2)" "unprognostic (1.63e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (3.28e-4)" "unprognostic (1.67e-1)" "unprognostic (8.25e-2)" "unprognostic (5.55e-3)" "unprognostic (4.82e-2)" "unprognostic (8.23e-2)" "unprognostic (8.16e-3)" 6.0 2.6 3.2 4.2 4.5 4.5 5.7 1.3 3.1 11.4 2.6 4.7 3.1 7.6 2.5 6.4 2.8 8.5 5.0 3.7 6.2 4.4 5.8 9.6 2.3 4.3 4.2 6.5 3.3 5.7 1.0 14.8 3.8 8.9 5.6 1.8 3.9 6.2 1.4 11.0 3.9 8.9 2.1 3.1 7.4 15.1 7.2 4.6 7.4 3.6 1.9 14.2 5.6 2.0 6.3 11.6 32.0 14.9 25.0 15.8 3.2 15.9 13.4 8.1 5.2 5.0 8.1 0.0 4.8 22.8 7.3 5.7 21.3 12.3 14.1 0.0 4.6 5.3 15.3 5.0 17.8 8.8 6.6 16.0 16.4 12.8 56.8 15.2 58.2 5.7 9.6 11.0 15.5 14.3 11.1 3.2 6.7 9.2 16.9 9.0 9.9 1.4 10.2 25.7 9.2 11.5 11.0 6.9 12.9 13.3 7.4 7.4 147.7 17.1 13.3 8.5 13.8 8.0 0.1 2.1 7.8 3.7 20.0 0.0 0.5 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.8 0.3 0.0 0.1 3.2 4.5 1.3 3.1 3.7 6.2 4.3 4.2 3.8 2.1 7.2 2.0 18.3 32.1 24.6 10.7 0.9 40.4 21.7 17.9 24.5 2.8 12.2 7.1 9.0 12.8 12.5 5.5 0.0 2.9 2.7 7.3 0.0 9.3 41.0 6.6 14.2 21.5 8.4 5.0 15.1 20.1 29.0 16.5 11.7 7.7 5.1 20.4 29.6 8.8 5.3 21.9 42.2 3.7 18.3 13.4 13.0 55.6 6.8 12.6 10.6 30.9 12.8 2.7 0.0 30.7 13.4 15.1 2.8 12.0 0.6 11.7 3.7 4.7 11.0 0.9 0.0 10.9 17.5 17.2 11.2 33.0 30.7 4.1 1.2 33.7 5.3 18.0 ANXA2 "ANX2, ANX2L4, CAL1H, LIP2, LPC2D" ENSG00000182718 "Annexin A2" P07355 15 60347134-60402883 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2185.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5755.6;Pancreatic endocrine cells: 5217.8;Prostatic glandular cells: 4575.5;Urothelial cells: 4326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 4429.7;classical monocyte: 2762.3;intermediate monocyte: 2401.9;myeloid DC: 4018.8;non-classical monocyte: 2686.5;T-reg: 1681.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 174.7" "CAB004311, HPA046964, HPA061798" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 19000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" Cytosol "CAB004311: AB_626677, HPA046964: AB_2732537, HPA061798: AB_2732671" "unprognostic (1.61e-1)" "unprognostic (1.31e-3)" "unprognostic (1.84e-1)" "prognostic favorable (6.88e-5)" "unprognostic (4.06e-3)" "unprognostic (5.42e-3)" "prognostic unfavorable (2.54e-5)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.94e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (7.74e-2)" "unprognostic (2.55e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.59e-5)" 975.6 370.5 49.0 461.9 50.5 151.7 708.5 49.6 96.9 806.3 95.6 631.2 502.0 296.2 267.2 2185.3 388.4 453.9 393.0 47.6 79.4 358.3 185.5 878.3 200.7 90.0 83.6 187.0 324.3 344.0 163.9 650.4 84.9 399.3 606.1 30.2 933.4 386.4 304.8 1140.8 487.5 425.4 73.3 301.6 379.0 116.1 120.9 188.7 351.2 205.8 541.1 842.2 1256.7 80.1 4183.3 4421.4 223.6 105.5 2962.4 4744.2 971.0 4703.6 2968.4 2868.4 2534.9 2083.5 1903.6 10.0 3907.2 5983.6 2185.1 4304.9 992.9 8695.5 3113.5 846.8 103.9 78.2 1918.7 882.7 1782.0 4.5 59.9 2324.4 2278.6 2013.2 4335.0 3477.2 5455.0 58.4 320.9 447.9 6271.8 468.4 18.5 239.1 508.2 3444.1 3283.5 48.9 1198.8 226.6 5172.4 2410.7 295.1 171.9 1774.5 424.8 1942.8 2305.1 922.7 173.6 6336.8 2534.1 3406.8 8668.0 4807.4 172.6 616.3 83.8 2449.2 47.9 5206.0 4429.7 2762.3 355.0 603.8 2401.9 668.5 657.9 686.4 701.7 4018.8 412.1 77.0 313.9 73.6 287.1 2686.5 609.4 1681.4 3754.4 49.0 50.5 49.6 96.9 47.6 79.4 90.0 83.6 84.9 73.3 120.9 80.1 673.9 2141.0 414.8 0.3 101.3 2512.2 3396.9 5755.6 246.4 2.5 395.9 337.4 28.2 773.5 3086.6 560.9 0.0 1874.5 135.9 933.6 13.7 3941.4 93.0 855.9 457.1 772.0 103.4 38.7 0.2 2411.4 2714.4 1076.7 328.7 1376.3 105.7 97.5 474.0 64.2 1537.2 0.0 1.3 689.0 1668.2 429.6 1992.1 126.6 771.1 715.1 1417.6 15.9 1284.0 19.4 138.0 1.5 0.1 5217.8 920.9 638.7 144.5 4575.5 845.8 51.8 2446.8 8.1 184.1 437.7 831.1 13.0 29.3 789.7 2325.1 1150.1 224.1 8.6 749.9 4326.1 AP003108.2 ENSG00000256591 "Novel transcript" 11 61429220-61485822 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.7;dendritic cells: 1.4;Endometrial stromal cells: 1.5;Glandular and luminal cells: 1.4;Granulosa cells: 3.4;Respiratory ciliated cells: 1.5;Theca cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 28.0" "Low region specificity" "Detected in all" HPA039732 Approved NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "HPA039732: AB_10962868" "unprognostic (1.23e-1)" "unprognostic (8.61e-2)" "unprognostic (9.60e-2)" "unprognostic (4.91e-2)" "unprognostic (5.69e-2)" "unprognostic (5.98e-2)" "unprognostic (4.41e-2)" "unprognostic (6.40e-2)" "unprognostic (3.53e-2)" "unprognostic (5.83e-2)" "unprognostic (4.98e-1)" "unprognostic (2.28e-1)" "unprognostic (2.36e-7)" "unprognostic (5.74e-2)" "unprognostic (9.69e-2)" "unprognostic (1.40e-1)" "unprognostic (4.66e-3)" 5.1 4.7 2.7 4.0 3.1 8.7 4.0 3.0 3.9 5.9 2.6 2.7 2.2 3.6 3.1 3.4 3.2 4.8 7.0 3.1 3.4 3.6 2.4 3.8 4.6 3.2 3.3 2.1 2.0 2.3 1.3 3.1 3.3 3.3 3.3 1.0 2.6 2.7 1.8 1.7 2.6 4.2 3.0 4.4 3.4 2.9 3.2 7.7 5.1 5.9 4.8 5.4 1.9 3.1 6.8 3.3 3.8 6.1 9.7 8.1 2.0 8.9 7.6 6.6 6.2 2.6 4.5 7.1 14.5 8.3 5.5 3.0 4.5 6.3 3.9 6.3 5.3 5.4 0.9 0.9 11.4 4.2 2.0 15.6 3.8 9.8 7.8 4.2 16.7 9.2 5.8 6.0 10.9 5.3 14.1 4.0 8.5 5.8 4.5 8.4 5.8 8.6 4.4 5.4 3.0 3.8 3.7 3.5 12.6 2.5 4.9 4.8 28.0 8.4 4.7 4.5 5.0 2.2 9.5 4.8 7.2 5.5 6.3 5.9 8.0 8.4 11.6 7.3 14.6 5.9 11.5 11.8 6.3 6.8 13.2 12.3 11.2 7.4 6.8 6.8 12.9 10.2 2.7 3.1 3.0 3.9 3.1 3.4 3.2 3.3 3.3 3.0 3.2 3.1 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.0 0.6 3.7 0.0 0.3 1.4 0.0 0.0 0.2 0.0 0.7 1.5 0.6 0.0 0.0 0.0 0.2 0.4 0.3 0.0 1.4 1.3 3.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.6 1.5 0.0 0.0 APBB2 "FE65L, FE65L1, MGC35575" ENSG00000163697 "Amyloid beta precursor protein binding family B member 2" Q92870 4 40810027-41216714 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.9" "Group enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 586.1;Oligodendrocytes: 803.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "naive B-cell: 5.6" "Lineage enriched" "Detected in single" 14 "B-cells: 5.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 138.7;TIME: 192.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023542 Approved Approved Mitochondria No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA023542: AB_1844909" "unprognostic (4.43e-2)" "unprognostic (4.40e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (5.91e-3)" "unprognostic (8.13e-2)" "unprognostic (5.77e-2)" "unprognostic (4.00e-3)" "unprognostic (2.51e-1)" "unprognostic (1.21e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (2.19e-3)" "unprognostic (9.35e-3)" "unprognostic (3.92e-2)" "unprognostic (2.29e-2)" "unprognostic (2.61e-1)" 41.6 9.1 23.1 5.4 42.3 8.6 25.1 38.1 24.5 16.1 3.7 13.9 8.3 14.0 5.9 8.9 13.1 16.1 21.5 20.6 30.6 16.5 14.7 18.6 7.4 42.9 39.6 32.1 10.8 8.5 8.5 17.6 39.5 8.7 7.7 15.7 8.6 9.8 28.7 12.6 7.0 14.9 25.2 14.8 11.3 8.5 36.7 13.2 33.6 21.7 5.6 10.7 13.1 72.9 19.4 9.4 20.6 28.8 64.9 50.7 45.2 38.5 45.8 14.0 24.5 34.1 40.2 33.9 20.7 16.5 44.5 5.6 36.5 49.4 25.0 1.1 7.3 0.4 23.5 21.1 65.0 19.2 1.1 76.7 24.6 42.5 43.0 58.2 138.7 19.0 1.1 0.7 86.1 16.3 6.3 3.6 17.1 9.8 17.9 50.9 58.6 38.4 19.9 8.9 27.2 15.4 11.7 6.6 6.9 23.7 17.2 2.2 192.3 20.1 59.5 13.8 61.1 8.1 18.5 41.2 20.7 30.8 24.6 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 5.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 23.1 42.3 38.1 24.5 20.6 30.6 42.9 39.6 39.5 25.2 36.7 72.9 58.8 80.1 14.5 46.7 5.0 10.7 3.8 10.4 7.4 7.6 25.5 13.6 22.5 12.8 6.3 9.2 6.2 14.4 0.5 5.2 7.9 3.8 14.5 5.6 32.8 39.4 3.0 5.3 121.3 6.4 2.8 25.2 12.8 7.5 1.3 13.5 47.2 13.8 3.2 62.2 171.3 4.0 16.2 4.0 6.7 23.1 35.8 2.5 7.2 164.9 0.1 9.3 0.0 586.1 803.4 6.2 6.7 37.2 0.2 2.7 5.5 6.3 4.0 7.6 59.2 43.2 51.4 3.8 10.8 7.3 11.9 6.0 1.2 24.0 7.4 3.6 APLN "apelin, XNPEP2" ENSG00000171388 Apelin Q9ULZ1 X 129645259-129654956 "Predicted secreted proteins" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;placenta: 54.0" "Cell type enriched" "Detected in some" 7 "Endothelial cells: 68.2" "Group enriched" "Detected in all" 6 "glioma: 44.2;renal cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 6 "HUVEC TERT2: 502.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.50e-1)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.50e-2)" "unprognostic (5.94e-2)" "prognostic unfavorable (9.32e-4)" "prognostic unfavorable (6.09e-4)" "unprognostic (4.71e-2)" "unprognostic (2.25e-1)" "unprognostic (3.30e-1)" "unprognostic (9.12e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (1.55e-1)" "unprognostic (1.15e-1)" "unprognostic (2.26e-1)" "unprognostic (8.42e-2)" 4.7 9.2 19.9 2.2 21.2 0.0 3.0 19.0 24.0 0.6 6.8 1.0 0.8 0.7 0.3 0.6 1.2 0.4 12.6 15.4 23.8 7.5 1.4 13.4 0.1 30.1 25.9 2.4 0.3 1.0 5.4 54.0 25.4 1.1 0.3 0.3 0.6 0.5 3.7 1.5 0.8 1.9 29.7 0.7 1.2 1.1 33.6 0.3 0.9 1.1 0.2 3.4 0.4 35.8 0.2 0.6 58.5 0.5 1.9 3.6 0.0 0.2 0.0 1.1 1.8 0.0 0.0 0.0 6.2 0.2 2.5 0.0 1.4 14.1 1.0 0.0 0.1 0.0 0.6 0.1 0.2 3.3 1.4 7.7 0.1 7.2 0.0 0.0 502.1 1.7 0.1 1.9 2.6 0.0 0.2 0.7 1.5 0.0 26.8 0.3 0.5 0.9 0.0 0.0 2.0 6.2 0.2 0.1 0.0 0.1 0.1 0.9 86.2 2.1 0.2 36.5 2.1 0.8 0.0 0.0 34.0 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 21.2 19.0 24.0 15.4 23.8 30.1 25.9 25.4 29.7 33.6 35.8 3.0 0.0 1.3 8.1 0.0 0.1 0.1 0.6 0.0 0.0 0.2 9.4 6.8 0.0 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.2 0.0 0.1 0.1 68.2 0.0 0.0 0.1 0.0 0.7 1.0 0.0 0.2 1.3 0.0 0.0 0.3 0.3 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.2 1.8 1.9 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.4 0.6 0.0 0.2 0.0 0.1 1.2 0.2 2.9 0.0 0.0 APP AD1 ENSG00000142192 "Amyloid beta precursor protein" P05067 21 25880550-26171128 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Apoptosis, Cell adhesion, Endocytosis, Notch signaling pathway" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Alzheimer disease, Amyloidosis, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 870.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 38.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 38.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000157, HPA001462" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 26000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" Vesicles "CAB000157: AB_323833, HPA001462: AB_1078185" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (1.92e-1)" "unprognostic (3.69e-3)" "unprognostic (2.54e-1)" "unprognostic (8.22e-2)" "unprognostic (1.28e-1)" "unprognostic (9.45e-2)" "unprognostic (4.28e-2)" "unprognostic (5.35e-2)" "prognostic favorable (2.79e-6)" "unprognostic (3.77e-2)" "unprognostic (2.46e-1)" "unprognostic (5.23e-2)" "unprognostic (2.08e-3)" 249.9 498.0 413.0 157.4 457.6 134.4 447.5 413.1 572.4 264.2 396.8 357.2 226.4 281.1 293.3 178.6 308.1 350.8 389.0 456.2 405.3 532.5 298.2 279.4 78.9 425.0 481.9 306.2 323.5 278.6 155.4 451.9 448.7 260.6 328.5 209.3 270.7 343.6 107.5 218.6 200.3 379.9 419.7 154.4 213.5 165.6 426.4 159.2 469.9 176.0 78.2 304.9 151.7 523.5 388.7 489.9 538.4 448.5 707.7 869.8 559.8 757.1 1029.2 386.6 449.3 286.4 941.0 0.9 848.3 614.8 505.1 255.6 326.4 921.6 324.4 14.7 253.1 0.8 275.6 204.1 688.0 372.0 19.6 790.4 990.7 456.8 823.0 1584.3 1750.7 158.6 0.8 39.0 614.5 433.1 6.5 4.0 416.2 644.9 418.6 241.2 505.2 325.3 1283.3 270.1 267.3 385.6 824.0 549.0 393.4 720.0 482.4 400.1 1837.1 850.8 350.2 310.4 371.6 232.3 3.1 4.8 690.4 1.6 836.3 1.1 7.5 0.0 0.2 2.2 0.3 0.8 2.2 0.7 5.6 2.2 2.3 0.6 1.5 0.5 1.6 38.1 0.6 3.3 413.0 457.6 413.1 572.4 456.2 405.3 425.0 481.9 448.7 419.7 426.4 523.5 330.2 109.0 39.6 70.5 47.6 181.6 215.6 449.0 306.7 45.2 280.3 199.6 143.2 296.0 214.0 502.1 29.2 472.6 180.7 395.2 56.7 398.7 46.1 78.8 162.2 416.0 162.6 29.2 481.6 180.4 141.2 309.5 164.7 110.7 8.2 100.3 539.7 125.7 76.3 84.1 525.5 303.1 256.3 61.6 79.9 61.8 242.6 69.9 161.9 189.3 89.9 329.9 4.1 423.2 870.8 205.4 223.1 296.8 24.0 187.5 95.2 165.8 164.7 24.5 118.3 336.5 198.5 38.3 86.9 85.9 106.1 552.1 27.0 111.4 283.5 133.6 ARAP3 "CENTD3, DRAG1, FLJ21065" ENSG00000120318 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" Q8WWN8 5 141653401-141682230 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 33.2;Endothelial cells: 28.3;Hepatic stellate cells: 28.5;Horizontal cells: 38.7;Microglial cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.3;neutrophil: 2.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 39.4;HUVEC TERT2: 74.3;TIME: 53.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042887 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042887: AB_10796681" "unprognostic (1.98e-1)" "unprognostic (4.88e-2)" "unprognostic (9.30e-2)" "unprognostic (1.31e-1)" "unprognostic (5.58e-2)" "unprognostic (5.26e-2)" "unprognostic (3.77e-3)" "unprognostic (9.76e-2)" "unprognostic (3.43e-2)" "unprognostic (1.39e-1)" "unprognostic (4.42e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (4.96e-2)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.98e-2)" 11.4 4.1 4.6 5.4 4.7 6.2 10.1 5.2 5.4 9.5 1.5 4.5 3.2 7.5 5.4 3.2 7.8 6.7 14.1 3.3 2.9 7.8 2.1 15.8 2.3 4.1 4.4 3.7 2.5 5.3 5.1 11.9 4.4 7.4 2.6 3.9 3.9 5.8 7.0 2.6 4.6 5.9 3.1 7.3 4.3 1.6 6.3 0.7 8.5 9.2 1.2 7.8 7.3 2.9 11.9 7.5 29.4 0.0 1.8 4.5 0.3 7.0 7.9 7.2 9.2 4.7 0.9 0.1 39.4 2.6 11.7 12.8 5.0 16.8 5.5 0.2 2.1 11.0 12.6 0.1 8.2 0.9 0.4 8.3 7.6 3.9 8.9 20.1 74.3 0.0 0.8 0.1 1.0 0.3 0.0 9.5 17.4 3.9 9.4 0.2 2.3 0.0 0.8 5.4 0.5 24.7 15.1 0.8 12.7 10.6 0.4 2.8 53.3 4.8 10.8 1.3 14.7 0.0 0.1 0.1 12.4 12.6 24.3 0.3 0.5 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.1 0.2 4.6 4.7 5.2 5.4 3.3 2.9 4.1 4.4 4.4 3.1 6.3 2.9 33.2 3.2 8.6 0.3 0.3 0.5 1.7 3.1 0.0 6.1 0.9 2.2 5.2 0.0 2.6 1.8 0.0 0.1 1.6 1.3 0.0 1.2 0.0 0.7 2.3 28.3 0.0 0.0 2.4 0.7 0.1 2.2 1.1 1.2 1.3 0.0 28.5 0.3 1.3 38.7 3.2 1.3 2.0 4.4 2.1 0.6 0.3 2.2 0.0 15.0 2.7 3.6 2.1 1.5 0.1 4.6 1.8 1.5 1.6 2.8 0.0 0.1 0.9 0.9 0.0 1.2 3.3 0.5 0.9 0.8 0.4 0.1 1.5 0.4 2.7 3.6 ARHGAP24 "DKFZP564B1162, FilGAP, FLJ33877" ENSG00000138639 "Rho GTPase activating protein 24" Q8N264 4 85475150-86002668 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 99.8" "Group enriched" "Detected in many" 4 "Astrocytes: 1364.3;Microglial cells: 905.0" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 15.9;memory B-cell: 47.3;naive B-cell: 36.8;plasmacytoid DC: 12.7" "Group enriched" "Detected in many" 5 "B-cells: 47.3;dendritic cells: 12.7;monocytes: 15.9" "Cell line enhanced" "Detected in many" "ASC diff: 109.0;ASC TERT1: 65.5;HHSteC: 63.6;HUVEC TERT2: 121.9;RPTEC TERT1: 67.2;TIME: 87.0;U-138 MG: 59.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014288 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" "HPA014288: AB_1844994" "unprognostic (2.19e-1)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.95e-2)" "unprognostic (2.81e-1)" "unprognostic (9.22e-2)" "unprognostic (5.75e-3)" "unprognostic (4.28e-3)" "unprognostic (3.66e-1)" "unprognostic (1.33e-1)" "unprognostic (5.91e-2)" "unprognostic (6.45e-2)" "prognostic favorable (1.67e-11)" "unprognostic (1.75e-2)" "unprognostic (6.86e-2)" "unprognostic (2.50e-2)" "unprognostic (8.75e-4)" 14.6 2.2 6.5 7.5 5.1 18.7 9.2 6.2 5.8 5.5 3.9 7.4 7.3 9.4 4.6 6.1 4.1 10.9 27.3 5.7 6.6 99.8 9.5 15.7 10.5 15.7 11.5 5.5 30.1 8.1 5.4 22.4 17.2 5.4 6.1 8.4 10.6 7.2 10.2 7.0 10.3 14.1 12.1 16.4 26.0 3.4 10.4 7.5 27.8 7.7 15.5 9.1 5.6 19.1 3.0 6.2 4.4 0.1 109.0 65.5 4.8 21.5 28.5 5.2 8.4 0.1 0.0 2.8 7.4 48.8 6.4 0.0 0.2 9.0 11.0 0.0 1.2 3.6 0.6 0.2 63.6 0.4 0.0 48.4 0.9 10.3 4.7 23.9 121.9 0.0 6.6 0.4 46.1 0.0 0.1 0.0 0.3 1.5 11.3 0.6 22.4 11.8 67.2 0.0 2.3 2.3 2.5 3.5 7.8 4.7 0.4 0.2 87.0 59.9 1.2 4.4 0.3 0.3 0.0 3.9 10.1 2.2 19.9 0.0 15.9 0.0 0.0 3.0 0.0 47.3 0.0 0.0 3.8 36.8 0.0 0.0 5.5 0.0 2.3 12.7 0.0 3.1 6.5 5.1 6.2 5.8 5.7 6.6 15.7 11.5 17.2 12.1 10.4 19.1 14.0 57.7 28.8 1364.3 142.1 8.2 3.9 35.6 10.2 6.6 1.2 4.7 26.4 47.1 18.3 46.0 6.2 54.8 9.9 1.0 226.9 9.4 30.5 1.2 12.9 9.5 2.4 0.0 12.2 11.8 26.2 24.7 25.0 1.4 1.3 6.7 4.2 9.5 10.5 111.0 51.3 3.3 6.1 33.7 21.3 8.8 16.8 26.3 19.6 905.0 34.0 27.7 0.0 27.2 21.8 7.4 2.9 12.4 2.0 2.3 0.2 205.9 24.8 6.6 6.6 50.0 21.3 8.1 5.9 4.0 6.3 232.9 4.1 18.4 5.0 1.9 ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 47.7;breast: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 66.4;Endothelial cells: 48.9;Hepatic stellate cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "HUVEC TERT2: 40.4;TIME: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA044443: AB_10960424, HPA063495: AB_2685023" "unprognostic (3.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.18e-2)" "unprognostic (7.09e-3)" "unprognostic (3.82e-1)" "unprognostic (7.29e-4)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "unprognostic (9.56e-3)" 47.7 5.9 4.6 4.1 4.2 0.0 41.6 4.1 4.7 8.7 3.0 6.9 3.1 10.9 1.6 4.8 9.8 7.3 35.5 4.1 4.1 15.8 2.9 22.1 3.1 4.7 4.5 3.8 4.2 3.4 4.0 14.7 4.8 8.0 2.0 0.2 5.1 3.5 13.2 7.7 6.5 7.2 4.0 7.9 6.9 2.2 5.2 1.6 12.4 10.9 1.8 12.3 8.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 49.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.2 4.1 4.7 4.1 4.1 4.7 4.5 4.8 4.0 5.2 3.6 66.4 0.0 3.0 0.3 0.5 2.8 0.3 0.0 0.6 0.8 0.5 0.4 8.9 2.8 0.0 1.8 0.0 0.0 0.2 0.1 0.0 0.0 3.3 0.4 0.2 48.9 0.0 0.0 0.2 0.0 0.1 1.0 0.0 1.3 0.0 0.0 37.1 0.0 0.1 0.0 0.5 0.0 0.0 1.4 2.8 4.4 0.0 0.5 7.2 11.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.1 0.0 1.6 1.5 0.4 0.2 0.2 1.0 0.1 0.3 0.7 0.0 0.3 ART4 "ARTC4, CD297, DO, DOK1" ENSG00000111339 "ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)" Q93070 12 14825569-14843526 "Blood group antigen proteins, CD markers, Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 53.3;lymphoid tissue: 19.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 15.7;Endothelial cells: 12.9;Erythroid cells: 51.3;Hepatic stellate cells: 66.0;Hepatocytes: 30.2" "Group enriched" "Detected in some" 5 "liver cancer: 3.8;pancreatic cancer: 1.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.0;HEL: 12.1;Hep G2: 7.3;HUVEC TERT2: 27.0" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Low region specificity" "Detected in all" HPA075664 Approved "Rods & Rings" "Secreted to blood" NA NA 17000000 "Cluster 85: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" "Rods & Rings" "HPA075664: " "unprognostic (2.50e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-1)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.90e-2)" "unprognostic (2.62e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-3)" "unprognostic (1.05e-1)" "unprognostic (1.71e-1)" 2.6 2.7 0.3 1.1 0.5 4.6 1.8 0.1 0.4 0.9 0.4 0.6 0.0 0.8 0.3 0.9 2.1 9.0 9.0 0.3 1.1 3.6 53.3 3.2 8.6 0.5 0.4 0.5 2.3 0.3 0.1 7.0 0.4 0.3 0.5 0.3 0.7 0.4 0.3 0.3 0.6 1.1 0.2 19.0 0.3 0.2 0.4 1.9 3.6 0.2 2.3 0.6 0.5 0.6 0.0 0.0 0.2 6.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 7.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.1 0.4 0.3 1.1 0.5 0.4 0.4 0.2 0.4 0.6 0.7 0.0 1.1 0.7 0.2 0.3 0.8 0.0 0.0 2.4 0.2 0.1 1.5 15.7 0.0 1.8 12.5 0.9 0.1 0.0 0.0 0.9 0.4 0.2 0.1 12.9 0.0 51.3 0.2 1.9 2.5 1.9 0.0 0.1 0.0 0.0 66.0 30.2 0.1 0.0 0.2 0.0 0.0 4.7 1.3 0.3 1.8 0.1 1.8 0.0 0.0 0.3 1.0 0.0 0.3 0.6 0.0 0.0 0.0 0.2 0.0 0.2 0.0 11.8 6.6 0.5 1.2 0.1 0.1 0.0 0.1 0.3 0.2 0.0 0.0 0.4 ASAP2 "CENTB3, DDEF2, KIAA0400, PAP, SHAG1" ENSG00000151693 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 2" O43150 2 9206765-9405683 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 46.8" "Cell type enhanced" "Detected in many" "Astrocytes: 141.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 7 "basophil: 2.7" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018615 Approved Supported Cytosol NA NA 260000 "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB018615: AB_2242947" "unprognostic (1.19e-1)" "unprognostic (2.66e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (3.06e-2)" "unprognostic (1.08e-3)" "unprognostic (1.69e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (4.68e-4)" "unprognostic (8.33e-2)" "unprognostic (1.58e-3)" "unprognostic (3.14e-1)" "unprognostic (3.16e-1)" "unprognostic (2.64e-2)" "unprognostic (3.24e-2)" 12.4 3.3 3.9 5.6 11.8 0.7 6.8 11.0 9.1 11.4 4.7 17.7 13.8 12.8 10.0 8.8 10.7 10.1 9.6 6.3 7.0 23.7 3.8 10.0 2.8 8.1 6.1 7.7 7.8 9.9 9.5 10.4 8.9 5.2 16.1 8.8 5.6 9.2 2.5 13.1 13.6 13.9 0.8 1.5 24.3 46.8 3.2 2.7 19.1 6.4 3.1 8.5 7.8 7.0 34.8 19.9 35.8 21.2 26.0 35.9 5.9 34.4 27.7 24.9 24.9 13.9 51.0 0.1 29.8 39.2 54.7 32.8 19.9 60.6 30.6 25.1 8.1 8.0 15.4 24.1 63.1 0.0 2.4 13.6 24.5 30.1 96.8 74.5 51.9 6.4 3.7 3.6 97.8 21.1 10.2 2.0 16.9 49.5 23.2 19.5 53.7 6.5 48.7 26.7 15.6 59.6 28.7 18.9 30.7 18.7 13.1 5.5 81.8 41.6 1.9 32.5 31.7 0.0 0.2 0.1 30.4 0.2 54.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 3.9 11.8 11.0 9.1 6.3 7.0 8.1 6.1 8.9 0.8 3.2 7.0 41.0 19.2 8.3 141.0 1.4 37.2 22.8 16.6 14.8 28.2 8.4 7.7 1.6 4.3 12.9 35.0 0.0 1.6 0.3 60.7 50.9 15.4 67.0 14.9 20.8 36.1 9.1 0.0 76.2 14.0 0.3 26.0 52.5 26.8 1.3 9.7 51.8 4.4 12.8 6.7 46.5 40.8 20.3 4.4 12.9 50.7 2.8 10.6 33.8 39.4 7.9 20.4 0.0 48.2 55.0 62.1 45.4 3.8 0.2 33.8 21.6 31.1 12.9 5.3 26.3 24.9 35.3 39.8 8.9 5.5 32.1 0.4 1.2 1.6 21.4 53.3 ATF6 ATF6A ENSG00000118217 "Activating transcription factor 6" P18850 1 161766298-161977574 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005935 Approved NA NA 46000000 "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "HPA005935: AB_2667472" "unprognostic (1.31e-1)" "unprognostic (5.15e-3)" "unprognostic (3.18e-2)" "unprognostic (8.43e-3)" "unprognostic (1.59e-1)" "unprognostic (5.58e-3)" "unprognostic (1.24e-1)" "unprognostic (5.32e-2)" "unprognostic (3.37e-2)" "unprognostic (3.24e-1)" "unprognostic (6.09e-3)" "unprognostic (3.38e-1)" "unprognostic (7.55e-2)" "unprognostic (2.03e-1)" "unprognostic (2.43e-1)" "unprognostic (1.56e-2)" "unprognostic (7.57e-3)" 13.6 10.1 7.2 13.9 8.4 12.6 11.5 8.3 7.5 8.4 13.6 9.9 9.9 10.6 18.9 11.0 8.9 11.3 9.4 7.2 9.9 14.6 22.0 11.4 10.6 10.2 9.4 9.0 34.4 18.9 7.1 18.0 10.5 10.7 11.2 16.7 13.3 10.3 8.9 11.2 9.4 12.8 10.0 11.3 11.2 10.1 8.0 8.4 15.1 9.5 11.1 13.7 7.9 11.9 23.3 17.9 15.1 22.4 18.6 17.7 26.7 27.8 25.3 17.7 19.2 11.6 38.2 16.9 39.6 34.6 19.9 34.0 15.1 18.6 17.6 23.2 12.9 15.9 22.6 12.7 40.3 29.7 40.6 18.3 29.0 18.2 53.3 23.8 40.3 22.7 37.9 19.2 19.3 23.0 15.9 17.3 12.2 24.5 23.1 13.7 21.4 39.2 19.3 11.1 9.1 13.8 33.3 19.8 41.0 32.9 24.5 39.2 54.4 23.2 21.9 8.7 31.5 28.0 29.2 20.4 28.2 5.1 29.0 9.7 17.8 12.0 9.2 18.3 9.0 8.7 8.3 7.7 12.8 9.5 9.5 9.7 33.2 7.4 24.4 5.7 9.6 10.6 7.2 8.4 8.3 7.5 7.2 9.9 10.2 9.4 10.5 10.0 8.0 11.9 40.5 102.5 85.1 41.8 31.4 34.8 45.4 28.4 18.2 38.6 38.0 25.4 21.6 25.8 67.0 51.5 50.1 49.2 23.2 30.5 7.9 45.9 13.0 27.1 25.3 49.8 37.1 17.9 79.9 37.6 43.1 46.2 23.9 40.2 54.3 24.0 37.5 53.5 50.3 26.9 69.7 28.2 30.5 59.5 59.4 10.8 23.0 66.6 26.6 103.0 62.0 34.1 21.6 60.3 105.8 35.9 15.6 24.5 53.9 43.3 22.3 18.8 61.7 29.9 6.6 61.3 31.8 43.1 30.5 22.7 47.7 103.0 29.0 22.1 22.9 44.1 ATF7 ATFA ENSG00000170653 "Activating transcription factor 7" P17544 12 53507856-53626410 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 141.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003384 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA003384: AB_1078234" "unprognostic (2.20e-2)" "unprognostic (3.10e-2)" "unprognostic (2.48e-2)" "unprognostic (7.96e-2)" "unprognostic (2.54e-1)" "unprognostic (4.73e-2)" "unprognostic (1.54e-2)" "unprognostic (9.16e-3)" "unprognostic (3.59e-3)" "unprognostic (8.03e-2)" "unprognostic (1.76e-3)" "unprognostic (2.59e-1)" "unprognostic (3.28e-3)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.51e-1)" "unprognostic (3.37e-1)" "unprognostic (1.17e-1)" 26.4 13.2 12.4 18.1 19.6 15.4 23.9 26.1 16.7 21.1 11.5 21.9 12.6 24.4 14.5 22.4 17.8 18.1 20.6 15.1 15.5 17.4 14.6 20.2 13.2 20.8 16.9 24.6 18.4 14.2 11.5 18.3 21.8 19.0 21.1 15.3 24.2 14.6 30.5 24.6 14.0 25.9 14.8 14.3 18.0 12.6 18.2 16.4 16.4 22.2 15.7 19.9 20.9 29.1 16.6 32.1 16.6 18.2 30.8 39.1 10.8 19.6 20.1 21.3 14.2 23.0 25.2 25.8 25.4 24.2 8.7 20.2 13.0 21.7 19.2 25.2 16.7 22.6 37.4 24.8 20.7 29.0 16.1 30.7 28.1 26.5 29.9 35.3 42.6 14.0 26.0 23.2 32.1 30.9 17.6 20.2 16.3 18.7 17.4 22.9 19.7 24.9 32.3 21.2 13.8 14.6 29.9 21.7 30.8 16.0 29.2 17.6 31.4 25.2 17.7 20.2 17.9 11.4 14.6 16.2 20.6 27.1 23.6 15.3 13.8 13.8 7.4 19.1 7.6 10.5 10.1 7.5 10.8 11.5 7.2 8.6 8.6 14.2 14.1 7.5 10.4 8.8 12.4 19.6 26.1 16.7 15.1 15.5 20.8 16.9 21.8 14.8 18.2 29.1 30.5 12.8 17.3 83.2 16.3 22.2 24.0 35.9 25.6 9.4 33.3 31.1 18.2 22.8 23.4 14.7 25.0 22.2 14.0 21.4 37.2 30.3 32.2 16.5 23.1 25.4 18.6 13.2 29.0 31.6 25.0 23.8 17.3 22.5 28.6 25.0 28.9 14.7 25.3 10.1 29.7 20.3 24.4 24.1 23.1 35.8 27.1 24.9 24.9 55.3 24.0 23.9 17.5 40.7 141.9 27.5 13.8 24.5 12.5 25.0 17.9 46.0 17.0 10.9 26.3 25.6 27.5 9.9 17.9 34.1 28.8 27.9 17.3 20.2 18.4 28.9 ATG4A "APG4A, AUTL2" ENSG00000101844 "Autophagy related 4A cysteine peptidase" Q8WYN0 X 108091668-108154671 "Enzymes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036374, HPA064759" Uncertain Approved "Actin filaments,Microtubules" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" Microtubules "Actin filaments" "HPA036374: AB_10672354, HPA064759: AB_2685346" "prognostic unfavorable (1.36e-5)" "unprognostic (1.41e-2)" "unprognostic (3.65e-1)" "unprognostic (2.52e-1)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "unprognostic (2.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.14e-1)" "unprognostic (2.62e-2)" "unprognostic (4.09e-1)" "unprognostic (1.03e-3)" "unprognostic (7.53e-2)" "unprognostic (2.98e-1)" "unprognostic (5.02e-3)" "unprognostic (1.20e-2)" 8.1 8.5 4.9 7.8 5.2 9.1 7.7 5.2 6.1 7.6 10.4 12.1 12.8 4.7 11.6 8.9 5.6 7.7 11.8 4.7 5.2 14.1 18.1 8.9 8.2 5.3 5.0 2.8 17.2 12.4 6.1 8.0 5.4 5.9 13.1 5.7 13.0 7.1 18.5 5.8 11.4 7.7 5.0 7.7 11.2 2.4 5.7 11.2 11.4 18.6 11.1 8.9 5.1 5.4 13.0 6.5 4.1 7.8 38.2 13.2 5.1 17.5 11.2 9.1 10.6 5.3 6.9 14.0 15.7 14.0 14.5 6.0 11.9 13.0 13.5 24.1 12.9 6.0 10.3 3.7 8.4 13.0 18.8 13.4 13.9 11.1 4.8 8.4 84.9 19.5 18.5 43.5 16.6 12.8 12.1 11.9 7.8 23.6 18.4 8.2 6.9 20.3 13.2 11.3 5.9 4.5 11.2 13.9 7.9 12.4 7.0 11.5 24.0 5.7 2.6 19.1 9.8 20.2 24.0 15.1 11.1 14.6 8.1 28.1 7.8 15.1 11.7 11.3 8.4 9.2 8.9 11.4 10.6 9.9 7.1 12.0 2.4 12.3 7.8 5.4 10.3 8.7 4.9 5.2 5.2 6.1 4.7 5.2 5.3 5.0 5.4 5.0 5.7 5.4 13.6 3.2 10.3 9.1 8.1 5.1 4.9 13.5 2.8 3.2 7.0 4.6 17.4 7.2 12.8 5.5 4.2 6.2 12.4 19.1 27.4 9.6 7.0 10.6 7.4 12.9 6.7 36.7 7.9 17.9 7.5 4.6 8.2 6.0 3.8 3.3 9.7 15.4 9.0 1.7 8.4 9.0 30.5 4.1 3.6 10.0 2.8 7.3 14.2 4.7 6.7 10.3 18.6 7.1 11.6 16.6 8.0 7.5 23.5 5.6 14.7 24.7 17.2 5.0 0.0 4.5 6.9 2.4 3.9 5.9 5.3 10.4 12.0 6.2 5.6 7.3 BCAP29 "BAP29, DKFZp686M2086" ENSG00000075790 "B cell receptor associated protein 29" Q9UHQ4 7 107580246-107629170 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029215, HPA049694" Supported Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA029215: AB_10602331, HPA049694: AB_2680854" "unprognostic (3.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.82e-2)" "unprognostic (1.05e-2)" "unprognostic (5.42e-3)" "unprognostic (4.71e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.43e-2)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (2.31e-2)" "unprognostic (7.36e-2)" "unprognostic (8.34e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-2)" "unprognostic (5.28e-3)" "unprognostic (1.81e-1)" 47.1 25.7 19.4 22.5 23.7 16.7 28.0 18.1 27.0 48.6 12.8 32.6 16.1 42.6 18.6 34.4 21.7 23.0 61.0 24.4 17.9 20.1 33.3 26.0 16.7 17.5 17.6 21.4 18.9 34.5 12.2 26.7 18.0 31.9 31.2 9.6 18.4 25.0 38.7 22.1 18.8 38.2 19.5 18.1 22.4 70.1 19.2 12.8 85.5 31.5 15.7 30.9 32.5 21.1 71.7 22.8 26.4 13.8 65.2 81.6 22.6 80.6 68.2 32.9 39.7 23.2 72.1 13.4 54.5 58.1 75.1 35.8 13.7 38.6 52.5 50.1 17.3 27.1 35.6 26.2 63.3 33.6 41.2 48.9 31.8 46.7 38.0 95.4 116.9 25.3 58.3 33.4 75.4 67.2 23.2 34.3 15.4 29.7 30.0 18.6 34.1 34.6 60.6 49.1 10.2 37.7 68.2 54.9 58.2 39.3 25.6 37.5 113.9 102.5 52.1 94.6 104.7 31.7 67.9 27.5 66.5 30.5 77.2 47.5 10.5 25.5 9.5 13.6 9.3 12.8 7.5 9.5 10.0 8.5 4.3 8.5 3.9 9.9 21.7 10.1 13.6 8.1 19.4 23.7 18.1 27.0 24.4 17.9 17.5 17.6 18.0 19.5 19.2 21.1 169.8 67.3 57.2 35.6 33.9 38.5 80.7 99.0 25.0 35.2 40.4 34.2 117.8 27.1 77.7 23.9 10.4 30.2 31.4 38.1 15.6 46.4 227.1 54.6 93.3 99.0 22.3 73.2 81.1 73.6 50.8 72.9 32.6 102.0 58.3 14.8 73.2 40.7 52.6 8.4 71.3 35.8 69.2 36.6 35.6 95.8 61.2 49.6 37.4 44.0 41.6 28.3 22.6 50.8 49.7 71.2 32.5 89.1 17.7 110.4 15.6 19.5 55.9 26.7 78.9 62.9 91.3 202.2 35.0 46.5 38.8 70.7 33.5 32.0 45.4 83.5 BCAR1 "CAS, CASS1, Crkas, P130Cas" ENSG00000050820 "BCAR1 scaffold protein, Cas family member" P56945 16 75228181-75268053 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000443, HPA042282" Approved Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB000443: , HPA042282: AB_2677929" "unprognostic (5.44e-2)" "unprognostic (2.96e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-2)" "unprognostic (2.17e-1)" "unprognostic (5.43e-3)" "prognostic unfavorable (9.11e-5)" "prognostic unfavorable (1.24e-4)" "unprognostic (2.15e-1)" "unprognostic (3.49e-2)" "unprognostic (5.18e-2)" "unprognostic (1.77e-2)" "prognostic favorable (4.55e-8)" "unprognostic (3.38e-1)" "unprognostic (3.60e-2)" "unprognostic (8.20e-2)" "unprognostic (2.20e-1)" 34.7 22.3 3.5 4.2 5.8 0.0 27.9 16.9 6.6 37.7 6.3 34.4 15.8 39.2 2.6 22.5 25.3 9.4 47.1 2.3 7.9 47.3 34.2 38.8 2.1 3.9 1.9 19.7 32.4 5.9 29.5 14.1 2.3 25.6 3.5 1.3 25.5 5.7 93.8 18.2 33.1 3.8 0.0 33.7 44.6 34.3 4.2 0.9 26.8 6.8 1.1 24.9 26.2 15.8 21.8 36.8 17.5 6.0 6.7 6.3 34.1 29.5 17.1 20.9 16.4 46.5 32.1 1.9 38.2 33.3 23.6 18.2 6.1 34.0 6.0 0.1 20.0 0.0 23.7 37.2 16.7 0.1 15.1 19.1 16.3 25.3 12.5 12.3 57.9 0.0 20.0 1.0 12.6 48.9 0.1 1.3 23.4 16.1 24.0 0.8 7.9 8.2 19.1 27.9 21.4 31.5 28.7 6.6 11.2 8.4 15.0 5.4 53.6 34.4 29.5 8.8 44.2 8.0 4.7 0.7 22.2 0.1 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 16.9 6.6 2.3 7.9 3.9 1.9 2.3 0.0 4.2 15.8 30.1 22.4 6.9 9.4 1.2 28.0 59.7 36.8 12.0 26.5 20.3 14.4 22.9 31.5 21.8 22.0 6.2 46.8 0.7 75.7 27.4 51.9 19.0 13.7 27.9 49.2 34.8 0.0 13.1 61.8 25.7 21.1 71.9 22.5 8.9 15.0 46.8 21.0 6.0 13.5 11.7 42.1 12.2 1.4 6.3 26.8 16.4 2.1 32.0 10.3 0.6 12.9 0.0 19.1 31.2 68.5 59.6 33.4 1.4 58.4 57.4 38.9 13.1 6.8 19.7 8.5 38.5 20.6 17.1 12.5 17.6 36.1 2.2 10.9 33.7 62.7 BCL10 "c-E10, CARMEN, CIPER, CLAP, mE10" ENSG00000142867 "BCL10 immune signaling adaptor" O95999 1 85265776-85276632 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 194.1;Paneth cells: 210.2;Urothelial cells: 297.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 97.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001944, HPA017925" Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB001944: , HPA017925: AB_1845312" "unprognostic (3.78e-3)" "unprognostic (2.53e-1)" "prognostic favorable (2.51e-4)" "unprognostic (1.61e-1)" "unprognostic (3.47e-1)" "unprognostic (2.61e-2)" "prognostic unfavorable (7.21e-7)" "unprognostic (7.06e-2)" "unprognostic (2.36e-1)" "unprognostic (9.46e-2)" "unprognostic (1.27e-2)" "unprognostic (1.73e-1)" "unprognostic (4.92e-3)" "unprognostic (3.18e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (1.07e-1)" 10.1 7.4 4.3 13.8 4.6 24.3 10.6 5.3 6.8 14.7 6.0 26.7 14.7 8.1 7.9 18.1 9.0 18.9 5.5 5.3 4.4 8.7 9.8 9.2 13.7 4.8 4.6 7.2 8.9 6.2 2.6 9.3 4.4 7.8 23.5 2.7 8.5 5.1 6.7 9.4 16.5 11.8 4.7 11.6 14.9 6.5 5.8 9.4 9.0 5.7 16.4 23.1 11.3 5.5 38.5 7.6 11.6 11.8 13.7 23.7 16.9 26.8 27.6 20.9 27.8 8.1 14.5 14.5 19.1 22.5 39.3 19.6 12.8 32.4 28.7 14.8 8.2 16.9 6.5 11.9 24.0 16.7 15.4 18.6 31.7 31.4 25.6 24.5 97.9 10.0 11.7 14.1 33.2 6.8 16.4 13.5 19.0 22.1 25.0 12.2 21.8 9.8 71.2 29.2 6.3 8.5 8.2 28.6 23.2 14.8 9.6 10.2 47.3 19.0 13.2 24.1 27.5 11.7 6.5 16.6 9.9 13.1 14.7 78.4 34.1 48.2 20.8 41.8 23.5 46.7 27.0 24.4 33.7 41.4 24.7 23.5 85.0 24.6 33.1 26.3 31.1 22.9 4.3 4.6 5.3 6.8 5.3 4.4 4.8 4.6 4.4 4.7 5.8 5.5 40.6 22.4 18.1 3.3 49.6 194.1 167.2 75.4 48.3 5.7 29.2 19.8 4.6 17.2 54.9 23.9 0.0 16.0 24.1 174.3 17.6 71.5 85.1 97.7 36.1 48.2 49.0 9.1 8.8 44.7 28.4 24.9 57.1 152.2 39.3 17.9 28.2 19.8 21.2 10.1 6.1 79.7 38.7 31.8 68.8 13.4 11.1 41.7 16.0 2.8 21.7 11.1 11.3 9.5 6.1 74.1 210.2 11.3 25.0 80.0 45.2 25.4 32.9 6.3 0.0 19.9 21.8 9.7 12.9 76.7 171.3 23.7 31.3 21.5 77.2 297.4 BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 37.8;Endothelial cells: 45.0;Hepatic stellate cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.2;HMC-1: 53.2;HUVEC TERT2: 96.2;TIME: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" 29.8 5.6 8.1 5.7 7.0 0.1 15.4 6.2 9.2 5.7 4.4 4.4 3.2 7.7 0.7 3.8 5.1 13.4 23.3 6.5 6.9 13.4 4.0 28.9 5.5 7.8 7.1 2.9 3.8 3.1 5.5 19.9 7.3 4.5 2.2 0.6 4.0 3.5 11.5 4.4 4.9 7.7 6.6 13.0 4.3 2.0 10.1 2.0 12.0 14.7 2.1 7.9 4.8 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 18.2 0.0 0.0 0.5 0.0 53.2 0.0 0.0 0.0 0.1 0.0 96.2 0.2 3.4 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 38.2 0.8 0.2 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.2 9.2 6.5 6.9 7.8 7.1 7.3 6.6 10.1 6.7 37.8 3.2 4.2 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.3 45.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 23.6 0.2 0.1 0.0 0.0 0.2 0.0 1.9 2.3 0.0 0.0 0.3 3.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.2 0.0 0.9 0.8 0.6 1.5 0.4 1.3 0.1 0.2 0.9 0.0 0.5 BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 23.0;Hepatic stellate cells: 16.8;Inhibitory neurons: 22.8;Microglial cells: 74.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 37.0;HUVEC TERT2: 149.6;Karpas-707: 81.6;SiHa: 70.0;TIME: 74.3;U-266/84: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Approved Mitochondria "Secreted to blood" No No 4970000 46000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" 16.5 3.1 5.1 2.2 5.9 0.4 12.7 3.9 6.2 3.2 7.8 3.7 3.0 3.5 0.6 2.0 2.4 2.1 5.1 3.9 3.7 17.8 1.9 9.1 1.5 4.9 4.5 8.2 0.6 0.6 4.6 18.1 4.7 2.8 2.7 0.1 2.3 2.6 3.1 3.5 3.0 2.3 4.8 4.6 4.7 2.2 5.7 0.9 1.5 1.3 2.4 3.3 3.0 4.1 0.9 2.4 0.3 0.0 0.4 0.3 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 37.0 1.1 1.6 0.5 1.1 0.2 0.0 0.0 5.7 15.9 21.8 1.4 0.8 1.1 16.7 0.0 0.0 0.7 2.4 9.6 149.6 0.0 0.0 81.6 0.0 0.3 0.0 0.0 0.8 0.5 12.0 0.6 0.0 15.3 0.5 0.0 12.3 0.0 70.0 0.0 0.0 9.3 0.0 0.0 74.3 0.0 4.7 0.5 2.6 11.3 41.3 0.1 2.3 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 5.1 5.9 3.9 6.2 3.9 3.7 4.9 4.5 4.7 4.8 5.7 4.1 23.0 0.0 0.5 1.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3.5 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.8 0.2 8.9 0.0 0.0 7.8 0.0 0.1 2.0 0.0 2.0 0.0 1.5 16.8 0.6 0.3 0.0 22.8 0.0 0.0 0.8 2.1 4.2 0.0 1.5 1.8 74.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.8 0.3 0.0 0.0 0.3 0.0 0.0 4.7 0.4 0.1 1.3 0.1 0.1 0.3 0.4 0.4 0.0 0.0 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376327-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.2;Inhibitory neurons: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.5 21.6 8.2 10.9 14.1 2.2 13.2 3.2 16.8 22.6 0.3 13.6 8.5 20.0 11.3 12.4 14.9 17.3 21.5 16.0 14.8 17.4 15.6 29.1 7.2 6.2 7.7 16.8 10.4 17.5 8.5 34.0 10.0 17.1 13.0 26.7 11.0 13.9 10.9 10.9 8.6 24.3 3.9 13.1 11.7 11.3 10.6 9.0 18.2 23.1 9.4 20.6 12.4 5.9 13.3 12.3 12.6 19.7 34.2 31.9 23.8 27.2 28.3 23.6 23.9 10.8 19.6 4.7 30.7 58.2 19.9 24.5 16.8 21.4 41.6 13.8 11.2 14.2 12.6 16.8 22.7 4.0 10.7 24.2 21.5 17.1 22.8 40.6 73.9 5.6 9.3 22.5 33.8 24.8 3.4 3.6 6.9 6.6 11.1 9.1 24.3 7.1 21.3 27.9 12.6 12.7 28.9 17.7 32.7 32.0 13.2 9.5 75.9 48.0 24.4 16.3 16.7 3.1 4.1 1.3 11.3 9.0 13.9 0.1 0.6 0.2 0.9 0.5 0.6 0.3 0.3 0.5 0.6 0.4 0.7 0.3 0.1 0.3 0.9 0.7 1.0 0.3 8.2 14.1 3.2 16.8 16.0 14.8 6.2 7.7 10.0 3.9 10.6 5.9 116.9 105.8 40.3 104.5 15.2 33.4 18.0 34.9 13.6 54.3 29.2 29.7 55.5 15.7 38.8 20.2 81.3 16.9 17.8 25.2 1.9 27.2 2.8 23.1 54.5 152.2 25.1 6.9 202.2 28.1 22.6 47.7 16.8 36.4 23.5 155.1 143.1 19.9 18.7 35.3 190.2 16.3 20.3 24.2 31.7 4.6 33.8 23.5 42.7 170.5 20.2 39.9 16.5 152.8 55.1 46.8 21.1 42.9 9.5 23.9 16.4 12.4 28.0 31.7 65.7 48.8 62.4 33.2 25.0 21.2 35.9 20.0 13.1 0.8 15.5 24.8 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "epididymis: 102.6" "Group enriched" "Detected in some" 4 "Endothelial cells: 28.2;Hepatic stellate cells: 93.9" "Cancer enhanced" "Detected in many" "melanoma: 3.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 77 "granulocytes: 7.6" "Cell line enriched" "Detected in some" 119 "HUVEC TERT2: 353.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 7.7 0.3 0.3 1.7 0.5 7.1 4.9 0.3 0.6 1.7 1.1 3.8 4.4 2.3 102.6 2.3 2.6 2.6 8.8 0.3 0.3 0.6 0.7 3.0 1.5 0.3 0.4 0.9 0.9 0.3 0.2 4.7 0.3 0.9 2.4 0.0 1.1 0.9 1.3 1.6 4.8 2.6 0.3 2.2 1.4 0.2 0.4 0.7 2.0 2.2 0.4 2.6 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 353.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.6 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.4 14.1 0.0 1.1 1.3 0.0 0.4 0.7 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.2 0.0 28.2 4.2 3.2 1.3 0.2 0.0 1.1 4.6 0.2 0.0 0.1 93.9 0.7 0.1 0.0 1.2 0.1 2.0 0.0 1.1 0.0 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.8 0.0 0.0 0.3 0.8 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.4 0.4 BOK "BCL2L9, BOKL, MGC4631" ENSG00000176720 "BCL2 family apoptosis regulator BOK" Q9UMX3 2 241551424-241574131 "Plasma proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 218.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 100.8;Oligodendrocytes: 47.0;Proximal tubular cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3" "Lineage enhanced" "Detected in single" "T-cells: 2.3" "Cell line enhanced" "Detected in many" "TIME: 65.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (6.16e-2)" "unprognostic (3.01e-2)" "unprognostic (1.24e-3)" "unprognostic (6.30e-2)" "unprognostic (8.63e-2)" "unprognostic (1.33e-1)" "unprognostic (2.24e-3)" "unprognostic (1.16e-2)" "unprognostic (8.45e-2)" "unprognostic (2.33e-1)" "unprognostic (2.47e-2)" "unprognostic (2.27e-1)" "prognostic favorable (1.09e-9)" "unprognostic (9.48e-3)" "unprognostic (6.81e-2)" "unprognostic (2.46e-1)" "unprognostic (1.09e-1)" 90.6 7.1 88.4 6.2 138.6 0.4 37.7 110.4 110.3 15.6 51.0 38.0 8.1 34.2 16.3 29.5 18.1 22.7 6.3 77.0 87.8 20.5 97.0 20.1 3.7 146.6 120.6 9.9 16.3 3.8 4.7 5.7 127.1 28.5 5.0 1.2 11.8 25.5 2.6 20.0 9.4 20.4 98.5 6.5 21.5 7.7 115.4 1.1 11.0 3.2 3.4 34.9 18.6 218.8 36.0 8.8 15.7 36.2 26.3 15.6 4.4 28.6 11.3 36.9 37.9 16.2 14.6 0.1 9.7 51.0 9.0 32.9 1.7 28.9 13.8 0.1 0.3 0.1 9.3 42.2 21.8 0.2 1.3 15.9 29.2 15.5 4.4 27.8 44.6 2.4 6.4 0.1 36.7 46.0 0.2 0.2 9.9 40.0 26.8 0.4 25.9 0.2 24.2 0.9 14.0 5.4 13.2 8.5 23.3 18.3 24.4 1.3 65.0 0.1 52.8 0.7 3.2 0.1 0.1 0.1 0.1 0.0 2.1 0.0 0.0 0.0 2.3 0.0 0.2 0.0 0.7 1.0 0.0 0.0 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.6 88.4 138.6 110.4 110.3 77.0 87.8 146.6 120.6 127.1 98.5 115.4 218.8 22.5 6.4 32.1 0.3 0.5 7.1 11.5 8.6 5.2 0.2 19.4 10.5 10.2 32.9 6.3 11.0 0.0 2.0 2.5 5.8 15.6 23.2 0.2 6.6 17.6 15.6 11.4 5.3 0.8 11.1 10.5 10.9 5.6 14.4 0.0 2.6 12.5 100.8 0.7 0.0 1.5 3.7 2.0 4.7 1.2 1.5 6.2 0.7 1.8 4.7 0.0 3.9 6.2 7.5 47.0 27.7 2.8 10.5 0.9 26.3 7.1 41.9 1.5 1.3 0.0 11.7 11.2 0.3 8.2 19.8 12.8 6.2 1.6 3.4 6.1 15.1 BTBD10 "GMRP-1, GMRP1, MGC13007" ENSG00000148925 "BTB domain containing 10" Q9BSF8 11 13388008-13463297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 116.5;Spermatocytes: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046777 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli fibrillar center" "HPA046777: AB_2679801" "unprognostic (2.38e-1)" "unprognostic (4.25e-1)" "unprognostic (1.75e-1)" "unprognostic (9.76e-2)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.07e-1)" "unprognostic (2.52e-1)" "unprognostic (3.00e-1)" "unprognostic (1.29e-3)" "unprognostic (1.15e-2)" "unprognostic (1.43e-1)" "unprognostic (1.32e-1)" "unprognostic (2.02e-1)" "unprognostic (6.98e-2)" "unprognostic (1.27e-1)" 13.8 12.2 19.8 13.6 30.9 13.4 13.3 18.8 27.9 15.0 3.2 18.1 13.1 16.5 12.0 28.6 11.8 15.2 17.7 25.9 18.6 11.4 9.8 13.0 15.7 12.0 15.7 14.1 8.7 13.2 14.1 17.4 16.2 15.0 20.3 18.8 10.8 17.4 14.6 13.1 11.7 21.1 10.0 12.6 17.7 38.3 14.5 18.5 13.6 18.4 17.4 27.1 17.8 22.2 55.9 40.2 34.3 23.2 30.4 29.5 43.5 57.5 33.3 43.5 39.4 37.7 64.0 38.1 27.1 42.2 43.9 44.0 26.3 61.4 50.8 38.7 27.1 20.7 13.9 22.5 46.9 27.6 45.4 25.3 68.0 25.2 57.3 33.0 89.1 26.8 11.8 38.2 46.0 33.7 28.3 15.2 14.9 50.0 34.9 24.8 29.4 23.8 69.7 44.3 14.8 20.9 34.4 27.5 20.5 38.9 19.7 14.7 81.7 44.7 37.2 43.4 33.6 14.2 52.6 25.5 30.6 23.6 38.9 41.1 24.8 38.2 18.1 39.7 21.7 18.4 17.1 20.1 29.2 17.2 19.1 19.3 64.9 25.7 50.5 12.7 23.6 18.3 19.8 30.9 18.8 27.9 25.9 18.6 12.0 15.7 16.2 10.0 14.5 22.2 20.5 16.0 7.0 35.9 16.9 28.2 40.7 27.0 15.9 13.9 9.6 8.6 14.0 12.8 19.7 5.5 4.2 24.3 18.1 15.7 5.9 31.8 95.7 14.3 12.5 22.6 16.3 9.0 116.5 25.2 54.3 15.3 27.5 19.1 22.8 11.1 11.7 5.9 22.9 8.4 74.2 14.2 28.5 16.4 13.0 26.3 9.9 13.0 17.8 38.4 22.2 9.9 18.6 61.9 62.4 50.2 14.2 18.4 12.0 30.1 8.7 10.5 19.9 14.1 6.6 13.4 20.6 121.3 59.7 27.8 35.8 62.1 17.8 9.2 13.3 64.6 BTBD19 ENSG00000222009 "BTB domain containing 19" C9JJ37 1 44808482-44815585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.0" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 9.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 5.4;HUVEC TERT2: 5.1;TIME: 11.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042633, HPA076404" Uncertain Uncertain Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA042633: AB_2678091, HPA076404: AB_2686796" "unprognostic (4.69e-2)" "unprognostic (8.74e-3)" "unprognostic (1.82e-3)" "unprognostic (1.20e-4)" "unprognostic (5.32e-2)" "unprognostic (3.80e-2)" "unprognostic (1.11e-2)" "unprognostic (1.20e-1)" "unprognostic (3.70e-1)" "unprognostic (1.53e-2)" "unprognostic (2.76e-2)" "unprognostic (1.92e-1)" "prognostic unfavorable (4.18e-8)" "unprognostic (2.20e-3)" "unprognostic (2.78e-2)" "unprognostic (8.29e-2)" "unprognostic (1.70e-1)" 2.7 4.3 0.4 1.1 0.4 0.9 1.4 0.5 1.0 3.8 9.0 1.1 0.4 5.4 0.7 0.7 4.0 1.2 2.0 0.5 1.2 1.5 0.8 2.3 0.4 3.2 2.1 4.2 0.6 1.5 5.3 0.8 2.0 1.3 0.4 0.0 0.8 1.2 0.4 0.6 1.1 1.6 1.4 0.9 1.0 0.7 1.7 0.1 3.2 0.4 0.3 1.1 2.1 1.5 0.1 0.9 0.8 0.8 1.7 2.0 0.6 1.7 1.0 0.7 1.6 0.0 0.7 0.0 0.7 2.9 0.4 0.2 0.0 0.8 0.3 0.8 0.1 1.6 0.3 0.9 1.8 0.0 1.2 3.0 0.1 2.9 0.5 5.4 5.1 0.0 0.2 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.1 0.9 1.0 0.0 0.0 11.9 3.0 2.3 1.4 1.3 0.4 0.1 0.0 1.8 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 1.0 0.5 1.2 3.2 2.1 2.0 1.4 1.7 1.5 5.8 3.2 4.2 0.0 1.4 2.0 1.9 0.8 3.4 0.1 4.2 1.8 1.3 1.5 2.9 1.8 0.0 0.4 1.2 2.6 0.0 0.9 0.6 3.8 6.8 5.2 0.0 0.4 0.6 0.6 0.4 6.2 2.0 7.3 2.5 1.1 6.1 3.3 2.9 0.0 0.3 1.7 0.0 5.9 6.2 0.1 3.1 8.1 3.6 1.9 0.5 1.1 0.0 0.5 0.1 1.0 1.4 1.2 2.3 1.1 2.6 3.3 1.5 0.1 0.0 9.3 4.5 1.0 0.2 2.1 2.3 1.2 2.7 4.1 1.0 1.4 BTBD9 "dJ322I12.1, KIAA1880" ENSG00000183826 "BTB domain containing 9" Q96Q07 6 38168451-38640148 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Astrocytes: 191.3;Excitatory neurons: 390.4;Inhibitory neurons: 257.0;Microglial cells: 142.4;Oligodendrocyte precursor cells: 193.5;Oligodendrocytes: 218.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041930 Uncertain Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA041930: AB_10795270" "unprognostic (4.40e-1)" "unprognostic (1.74e-1)" "unprognostic (1.75e-3)" "unprognostic (1.64e-2)" "unprognostic (6.59e-2)" "unprognostic (3.94e-2)" "unprognostic (1.48e-1)" "unprognostic (1.76e-3)" "unprognostic (5.44e-2)" "unprognostic (6.13e-2)" "unprognostic (1.92e-2)" "unprognostic (2.74e-1)" "prognostic favorable (4.20e-13)" "unprognostic (1.35e-1)" "unprognostic (6.56e-2)" "unprognostic (8.67e-2)" "unprognostic (1.15e-2)" 4.2 4.7 13.1 4.3 13.2 8.3 3.8 1.8 22.6 3.8 10.1 5.1 5.2 5.2 4.4 5.6 8.7 5.8 8.3 18.8 4.2 6.2 3.2 9.2 4.7 3.0 7.8 8.1 3.5 13.7 4.3 4.3 4.1 5.2 5.6 7.1 4.5 4.1 7.8 5.2 7.2 5.0 0.7 4.8 4.7 8.1 7.5 3.7 6.7 6.7 4.4 4.7 3.5 10.7 5.4 4.7 6.8 8.5 4.6 6.7 5.4 5.3 7.4 5.4 6.3 6.2 3.1 3.1 3.7 8.2 7.3 3.5 3.2 6.7 5.9 7.4 7.0 6.9 5.1 2.5 4.0 6.5 13.4 5.2 6.0 7.4 7.9 4.9 9.3 4.8 3.2 5.2 5.6 3.4 4.6 2.7 2.0 4.9 3.6 3.0 4.7 6.1 5.1 12.3 10.2 5.8 4.5 5.7 5.2 4.6 5.8 5.3 7.0 5.6 3.7 6.6 5.5 3.3 2.5 3.7 4.9 4.4 6.6 12.3 1.8 3.2 2.4 2.6 3.3 2.6 2.4 2.2 1.7 3.7 3.0 2.7 4.5 3.3 4.0 2.6 4.1 1.9 13.1 13.2 1.8 22.6 18.8 4.2 3.0 7.8 4.1 0.7 7.5 10.7 3.9 3.2 17.9 191.3 14.2 4.6 2.2 2.9 4.6 11.5 3.6 2.9 11.8 8.6 6.7 9.2 8.4 2.7 7.3 15.5 5.9 4.6 17.5 12.8 5.3 4.1 4.9 1.3 390.4 5.8 1.5 4.6 10.2 8.1 0.0 5.5 7.5 3.0 2.6 5.0 257.0 3.9 6.1 3.5 3.0 24.6 3.1 5.6 1.8 142.4 1.5 5.9 2.1 193.5 218.3 5.5 5.0 3.4 10.4 2.1 13.1 6.8 8.7 5.6 0.0 5.4 6.1 3.1 2.9 4.4 5.8 4.7 11.1 3.7 6.0 3.2 C11orf91 ENSG00000205177 "Chromosome 11 open reading frame 91" Q3C1V1 11 33698261-33700801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.5" "Cell type enhanced" "Detected in some" "Early spermatids: 16.6;Late spermatids: 4.0;Sertoli cells: 6.6;Spermatocytes: 12.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 16.2;hTERT-HME1: 10.0;HUVEC TERT2: 8.2;TIME: 12.6;U-2197: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047064, HPA050487" Uncertain Supported Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA047064: AB_2679920, HPA050487: AB_2681142" "unprognostic (9.22e-3)" "unprognostic (1.51e-2)" "unprognostic (1.76e-1)" "unprognostic (6.60e-2)" "unprognostic (1.62e-2)" "unprognostic (3.63e-2)" "unprognostic (2.31e-1)" "unprognostic (5.68e-3)" "unprognostic (7.41e-2)" "unprognostic (2.97e-2)" "unprognostic (1.99e-2)" "unprognostic (3.01e-1)" "unprognostic (8.33e-2)" "unprognostic (4.06e-2)" "unprognostic (3.95e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" 4.8 0.2 0.3 0.6 0.3 1.0 1.5 1.2 2.0 0.1 0.0 0.4 0.0 0.2 0.1 2.9 0.3 4.7 0.8 0.2 0.5 1.4 0.2 1.1 0.2 0.3 0.5 0.2 1.5 0.0 0.1 0.5 0.6 0.2 0.0 0.2 0.5 0.2 0.5 1.0 0.3 0.8 0.4 0.0 2.1 9.5 0.3 0.2 0.4 0.0 0.4 1.4 0.3 0.6 0.2 0.0 0.2 1.5 0.0 0.0 0.0 1.8 0.0 0.9 0.4 0.3 0.6 0.0 0.1 1.9 0.2 0.7 0.5 16.2 1.3 0.5 0.0 0.0 4.0 0.9 0.3 0.0 0.0 0.0 0.1 1.2 10.0 0.5 8.2 0.2 0.0 2.5 3.9 0.0 0.0 0.3 0.0 0.1 5.0 0.0 0.0 0.0 1.1 2.1 0.0 0.3 0.0 1.6 0.1 0.5 0.0 0.0 12.6 1.2 0.3 10.3 0.3 0.7 0.6 0.0 2.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.2 2.0 0.2 0.5 0.3 0.5 0.6 0.4 0.3 0.6 1.2 0.0 0.0 0.3 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 16.6 0.4 0.2 0.6 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 6.6 0.1 0.3 12.3 0.4 0.3 0.0 0.1 0.0 0.0 0.0 1.5 C1orf115 "FLJ14146, RDD1" ENSG00000162817 "Chromosome 1 open reading frame 115" Q9H7X2 1 220690363-220699153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 120.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 109.8;Hepatocytes: 121.3;Proximal enterocytes: 255.7;Syncytiotrophoblasts: 183.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 62.4;HUVEC TERT2: 49.7;TIME: 93.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (5.16e-2)" "prognostic favorable (6.52e-4)" "unprognostic (1.31e-1)" "unprognostic (3.93e-2)" "unprognostic (2.03e-1)" "unprognostic (5.69e-3)" "unprognostic (8.65e-2)" "prognostic favorable (5.12e-5)" "unprognostic (3.11e-1)" "unprognostic (1.33e-1)" "unprognostic (1.74e-2)" "unprognostic (4.24e-1)" "unprognostic (4.54e-2)" "unprognostic (9.21e-3)" "unprognostic (1.07e-1)" 50.0 6.8 32.3 6.8 43.4 0.3 28.4 10.8 45.8 14.8 17.3 30.9 112.4 12.5 21.3 5.7 14.4 10.3 18.9 47.5 11.5 52.8 101.4 23.4 8.5 13.1 10.5 17.9 12.1 20.5 17.5 70.2 13.5 31.1 23.3 8.9 74.1 10.6 14.6 9.1 120.9 11.8 10.0 50.0 22.4 7.2 15.9 3.8 16.5 19.3 9.5 6.9 7.2 25.9 1.6 7.3 0.5 10.1 0.0 0.0 29.0 2.0 8.1 4.2 18.3 7.3 7.6 0.0 3.1 0.6 8.5 0.2 16.9 3.4 3.8 0.0 16.9 0.2 1.5 62.4 9.4 0.0 0.2 1.3 5.7 0.3 2.1 0.0 49.7 0.0 4.7 0.0 0.3 6.7 0.0 0.5 12.3 20.4 5.2 0.0 0.1 0.6 9.0 9.8 5.3 7.4 0.0 12.3 30.9 17.5 20.0 0.4 93.6 0.0 0.1 0.3 1.7 1.1 0.0 0.0 0.2 0.0 1.5 0.0 0.2 0.0 0.2 0.0 0.1 0.5 0.2 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.3 43.4 10.8 45.8 47.5 11.5 13.1 10.5 13.5 10.0 15.9 25.9 76.7 3.2 6.7 1.6 5.8 3.4 4.2 1.4 1.8 17.3 29.8 20.4 19.5 17.2 5.1 31.3 6.2 74.4 0.9 109.8 39.2 9.7 1.5 7.6 1.3 51.5 8.4 8.0 20.7 16.6 68.2 5.6 2.0 11.7 0.0 59.0 18.9 121.3 6.4 0.0 2.0 25.6 6.1 4.7 2.7 2.8 3.1 1.4 8.8 5.6 4.8 10.4 0.0 0.0 1.4 13.9 55.5 19.2 0.0 11.0 255.7 58.2 1.9 3.9 0.0 2.1 4.6 0.5 5.5 0.8 1.7 183.9 1.2 54.9 25.1 2.6 C1QTNF5 "CTRP5, DKFZp586B0621, LORD" ENSG00000223953 "C1q and TNF related 5" Q9BXJ0 11 119338942-119340940 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Ductal cells: 4.7;Endothelial cells: 1.5;Exocrine glandular cells: 1.1;Fibroblasts: 3.6;Gastric mucus-secreting cells: 1.5;Smooth muscle cells: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 17.7;fHDF/TERT166: 14.7;HHSteC: 35.8;hTERT-RPE1: 28.5;HUVEC TERT2: 54.7;TIME: 50.5" "Low region specificity" "Detected in all" "CAB025607, HPA038604" Uncertain "Secreted to blood" NA NA 219000000 1500000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "CAB025607: , HPA038604: AB_2676110" 51.9 13.4 19.1 12.9 20.8 0.1 36.6 20.3 20.7 38.4 25.5 23.0 14.9 50.7 7.5 11.5 27.2 45.5 36.1 17.3 19.8 42.4 11.1 42.0 8.9 21.8 22.2 11.3 18.8 6.8 14.8 13.6 20.4 19.5 7.8 2.2 16.9 8.7 8.8 20.4 24.2 26.8 21.7 32.3 27.1 2.6 27.5 2.8 32.0 15.2 4.6 31.6 20.8 21.7 0.0 0.0 3.3 0.0 17.7 4.9 0.2 4.6 0.3 0.6 2.7 0.1 0.0 0.1 2.0 14.7 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 35.8 0.0 0.0 8.4 0.0 0.3 0.0 28.5 54.7 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.9 0.0 0.1 0.0 4.1 0.0 0.1 0.0 0.0 6.5 0.0 0.0 1.1 0.9 0.0 0.0 50.5 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 20.8 20.3 20.7 17.3 19.8 21.8 22.2 20.4 21.7 27.5 21.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 1.5 0.0 0.0 0.0 1.1 0.0 3.6 1.5 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 C2CD4B "FAM148B, NLF2" ENSG00000205502 "C2 calcium dependent domain containing 4B" A6NLJ0 15 62163535-62165285 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pancreas: 99.3" "Cell type enhanced" "Detected in many" "Adipocytes: 169.8;Endothelial cells: 116.2;Enteroendocrine cells: 214.4;Glandular and luminal cells: 128.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HUVEC TERT2: 1.9" HPA046880 Uncertain NA NA "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA046880: AB_10959458" "unprognostic (6.60e-2)" "prognostic favorable (4.22e-4)" "unprognostic (2.24e-2)" "unprognostic (1.25e-1)" "unprognostic (4.15e-1)" "unprognostic (4.06e-3)" "unprognostic (2.29e-1)" "unprognostic (5.02e-2)" "unprognostic (3.36e-2)" "unprognostic (2.33e-1)" "unprognostic (5.30e-2)" "unprognostic (1.83e-1)" "unprognostic (6.16e-3)" "unprognostic (7.89e-2)" "unprognostic (5.24e-1)" "unprognostic (8.64e-3)" "unprognostic (1.48e-1)" 23.1 1.2 1.5 0.6 1.0 3.0 19.6 0.8 1.2 7.2 0.5 2.5 2.2 4.1 0.0 1.6 2.8 1.6 6.3 0.9 0.9 5.5 1.9 13.0 0.4 1.5 1.3 1.0 99.3 0.3 6.5 0.4 1.5 2.3 0.4 0.0 1.6 0.2 2.8 4.7 2.4 0.7 1.7 0.5 24.4 1.0 2.1 2.7 2.7 1.3 0.0 5.0 2.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.8 1.2 0.9 0.9 1.5 1.3 1.5 1.7 2.1 0.9 169.8 3.2 5.5 0.0 0.1 6.8 3.0 0.1 0.6 0.8 14.5 4.3 1.3 5.7 0.9 1.8 0.0 0.0 0.9 6.1 0.0 2.1 0.0 40.4 15.2 116.2 214.4 0.0 0.0 24.0 0.0 3.2 17.9 128.9 2.5 0.0 11.4 0.4 0.4 0.0 0.1 22.5 6.1 1.0 12.1 0.0 0.0 1.3 3.6 1.9 1.6 0.1 0.0 0.0 0.0 9.8 1.3 0.0 0.1 2.4 1.3 0.0 0.1 0.6 0.0 6.8 4.1 0.1 0.4 0.8 7.0 0.0 1.7 0.5 4.3 3.5 C7orf61 IMAGE:4839025 ENSG00000185955 "Chromosome 7 open reading frame 61" Q8IZ16 7 100456620-100464260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 68.4" "Group enriched" "Detected in many" 20 "Early spermatids: 588.7;Late spermatids: 349.4" "Cancer enriched" "Detected in some" 5 "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 25.2;NB-4: 9.6;TIME: 14.9" HPA060395 Enhanced Approved Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA060395: AB_2684274" "unprognostic (1.88e-1)" "unprognostic (5.02e-1)" "unprognostic (1.26e-2)" "unprognostic (7.70e-5)" "unprognostic (1.65e-1)" "unprognostic (2.63e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (4.26e-1)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (2.53e-1)" "unprognostic (6.39e-13)" "unprognostic (9.54e-2)" "unprognostic (2.93e-1)" "unprognostic (1.33e-2)" "unprognostic (1.24e-2)" 1.3 0.6 11.5 0.5 14.7 1.4 0.9 12.5 13.4 2.0 7.4 1.6 0.0 0.9 0.3 0.9 1.4 0.5 1.2 11.0 12.4 1.0 0.8 1.6 0.8 13.7 13.3 3.0 0.3 0.2 2.9 0.6 13.1 1.5 0.1 1.9 0.5 0.6 0.5 0.8 0.9 0.2 11.1 2.6 0.7 68.4 12.7 0.8 1.1 0.6 0.3 1.1 1.3 16.3 1.0 0.2 0.8 0.9 0.9 2.2 0.3 0.4 1.5 0.2 0.8 1.1 0.5 0.7 1.7 0.9 1.4 0.7 0.3 0.0 0.6 1.0 1.7 1.4 2.2 0.0 1.2 0.5 0.4 0.3 0.4 0.9 1.4 2.4 25.2 2.4 0.7 1.3 1.5 2.4 0.5 9.6 0.6 0.3 1.1 2.5 0.0 0.5 0.4 0.4 0.0 0.0 0.6 0.8 1.5 0.5 0.4 2.6 14.9 1.3 2.2 2.8 0.4 0.3 0.2 1.0 0.3 2.3 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.3 0.3 0.2 0.1 0.0 0.6 0.0 11.5 14.7 12.5 13.4 11.0 12.4 13.7 13.3 13.1 11.1 12.7 16.3 1.7 0.0 0.0 16.0 1.0 8.3 0.5 0.7 4.6 1.7 2.9 5.5 1.4 1.5 0.4 0.0 0.0 0.2 1.7 0.4 0.0 0.5 588.7 0.8 1.2 2.2 0.0 0.0 1.2 0.0 0.4 2.0 0.0 1.1 0.0 1.5 0.7 0.0 0.9 3.3 1.5 0.4 0.0 0.3 16.8 349.4 7.8 1.4 5.4 0.0 0.7 7.4 0.0 4.5 14.1 0.2 0.1 3.8 0.0 0.7 0.5 0.1 0.4 0.1 6.6 1.7 1.8 22.9 2.6 1.6 6.1 0.1 2.2 0.4 0.4 0.4 CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.7;lung: 76.8" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Endometrial stromal cells: 92.7;Endothelial cells: 248.7;Hepatic stellate cells: 259.2;Oligodendrocyte precursor cells: 293.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cell line enriched" "Detected in some" 4 "HUVEC TERT2: 173.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA008070: AB_1845912, HPA046515: AB_2679681" "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" 70.7 6.3 3.4 12.3 4.0 0.4 15.8 6.1 4.4 27.8 3.4 6.9 6.0 21.5 4.6 8.6 11.4 24.4 20.4 3.9 3.8 14.0 12.6 76.8 7.9 11.1 6.2 15.7 4.3 13.0 3.6 11.7 10.8 7.3 9.5 0.9 7.1 7.7 6.2 3.9 6.3 27.1 15.5 8.6 7.1 2.7 3.9 4.6 28.3 20.2 9.1 14.1 4.7 15.2 0.2 0.0 8.8 0.0 6.2 1.6 0.0 0.8 1.3 0.1 1.0 0.0 1.0 0.0 2.3 0.7 0.2 0.0 0.0 0.6 0.2 1.5 0.5 1.5 0.0 0.2 4.9 0.2 0.0 4.6 0.2 0.3 2.1 0.5 173.6 0.1 0.0 2.5 1.2 0.0 0.8 0.1 0.5 0.0 0.0 0.0 3.1 0.5 40.5 0.0 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.2 25.3 0.7 0.1 0.1 0.4 6.2 0.1 0.7 0.4 0.0 0.0 0.0 2.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 9.2 0.0 0.8 0.1 0.1 1.0 1.0 2.6 0.0 0.9 3.4 4.0 6.1 4.4 3.9 3.8 11.1 6.2 10.8 15.5 3.9 15.2 138.3 0.0 11.9 19.6 1.2 9.3 2.3 1.7 21.6 0.2 0.8 1.8 12.3 2.8 3.6 0.0 0.0 0.4 2.4 0.0 3.9 0.3 0.8 3.1 92.7 248.7 0.0 4.8 15.4 0.4 0.2 56.5 1.1 1.7 5.1 12.3 259.2 1.8 0.9 0.0 2.1 0.0 2.0 10.3 29.7 1.0 7.8 15.4 10.6 47.8 16.1 0.0 1.0 293.0 1.0 0.1 0.0 2.6 4.9 1.9 0.0 13.2 2.8 0.1 6.6 4.1 21.5 1.3 0.7 18.2 6.8 0.3 3.0 6.0 0.0 1.8 CALHM5 "C6orf188, dJ493F7.3, FAM26E, MGC45451" ENSG00000178033 "Calcium homeostasis modulator family member 5" Q8N5C1 6 116511639-116524788 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 10.6;Endothelial cells: 2.6;Fibroblasts: 2.0;Granulosa cells: 2.6;Smooth muscle cells: 3.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 5.3;fHDF/TERT166: 5.6;HUVEC TERT2: 5.6;LHCN-M2: 5.9;TIME: 8.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034969, HPA034970" Uncertain Approved "Golgi apparatus" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA034969: AB_10670299, HPA034970: AB_2674390" "unprognostic (2.71e-2)" "unprognostic (1.56e-1)" "unprognostic (8.12e-2)" "unprognostic (1.01e-1)" "unprognostic (1.36e-1)" "unprognostic (3.92e-1)" "unprognostic (1.93e-2)" "unprognostic (5.37e-2)" "unprognostic (4.09e-2)" "unprognostic (4.21e-2)" "unprognostic (1.06e-1)" "unprognostic (9.16e-2)" "unprognostic (1.24e-7)" "unprognostic (1.16e-2)" "unprognostic (2.98e-2)" "unprognostic (7.69e-2)" "unprognostic (6.65e-3)" 3.3 0.5 0.6 1.1 0.7 0.0 1.6 0.5 0.6 1.3 0.7 1.5 0.6 1.3 0.6 1.2 0.9 1.5 2.3 0.6 0.5 1.9 0.5 1.7 0.9 0.6 0.5 0.5 0.1 0.5 0.3 4.4 0.6 0.9 1.0 0.0 0.6 0.7 1.6 1.0 0.9 2.1 0.5 1.7 0.6 0.7 0.8 0.1 0.8 2.5 0.5 1.4 1.2 0.6 0.0 0.0 4.5 0.0 2.7 4.3 0.0 3.6 5.3 1.4 3.8 0.2 0.0 0.0 0.3 5.6 3.8 0.0 0.0 0.0 1.5 0.0 0.2 0.8 0.0 0.0 0.6 0.0 0.0 2.6 0.0 3.4 0.0 1.0 5.6 0.0 0.0 1.0 5.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 8.9 2.5 0.8 0.3 0.2 0.0 0.0 0.0 2.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.6 0.6 0.5 0.6 0.5 0.6 0.5 0.8 0.6 10.6 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.6 0.0 0.0 0.0 0.7 0.0 2.0 0.0 0.0 0.0 2.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 CAPN11 ENSG00000137225 "Calpain 11" Q9UMQ6 6 44158811-44184401 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 30.3" "Cell type enhanced" "Detected in some" "Adipocytes: 14.0;Breast myoepithelial cells: 11.8;Early spermatids: 24.7;Late spermatids: 9.8;Spermatocytes: 50.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "NTERA-2: 2.2;TIME: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB018070, HPA030955" Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB018070: AB_2069481, HPA030955: AB_2673672" "unprognostic (2.20e-2)" "unprognostic (1.87e-1)" "unprognostic (1.64e-2)" "unprognostic (2.75e-1)" "unprognostic (6.22e-2)" "unprognostic (3.34e-2)" "unprognostic (3.99e-2)" "unprognostic (4.57e-2)" "unprognostic (1.29e-1)" "unprognostic (8.96e-2)" "unprognostic (1.01e-1)" "unprognostic (2.13e-1)" "unprognostic (3.62e-6)" "unprognostic (2.38e-2)" "unprognostic (3.51e-1)" "unprognostic (2.27e-2)" "unprognostic (8.89e-2)" 1.6 0.4 0.2 0.3 0.2 0.5 2.3 0.4 0.5 0.8 0.1 0.2 0.0 0.3 0.5 0.2 0.3 0.3 0.3 0.3 0.3 0.2 0.1 0.2 0.4 0.2 0.1 0.0 0.1 0.1 0.0 0.5 0.2 0.3 0.1 0.1 0.4 0.0 0.1 0.8 0.4 0.3 0.1 0.1 0.2 30.3 0.3 2.2 0.3 0.2 0.3 0.4 0.5 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.2 0.2 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 5.8 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.4 0.5 0.3 0.3 0.2 0.1 0.2 0.1 0.3 0.5 14.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 11.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 24.7 0.0 0.0 3.9 0.0 2.7 0.5 0.0 0.0 0.7 0.0 0.2 0.0 0.1 1.1 0.0 1.3 0.0 0.3 0.1 0.0 0.3 0.3 9.8 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.7 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.2 50.0 0.9 0.1 0.0 0.0 0.1 0.1 0.1 0.1 CARD6 CINCIN1 ENSG00000132357 "Caspase recruitment domain family member 6" Q9BX69 5 40841308-40860175 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 23.8;Gastric mucus-secreting cells: 26.5;Pancreatic endocrine cells: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 27.4" "Group enriched" "Detected in all" 5 "dendritic cells: 7.7;granulocytes: 27.4;monocytes: 13.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 20.5;HUVEC TERT2: 34.0;TIME: 36.9" "Low region specificity" "Detected in many" HPA036438 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA036438: AB_10670105" "unprognostic (8.57e-3)" "unprognostic (1.30e-1)" "unprognostic (3.43e-1)" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.40e-2)" "unprognostic (4.15e-2)" "unprognostic (3.12e-2)" "unprognostic (8.97e-2)" "unprognostic (1.50e-2)" "unprognostic (1.49e-1)" "unprognostic (9.37e-2)" "unprognostic (1.00e-1)" "unprognostic (2.93e-2)" "unprognostic (1.11e-2)" "unprognostic (8.88e-3)" 9.0 12.0 1.7 5.5 1.9 3.1 5.8 1.9 1.9 4.8 3.3 2.6 7.8 3.5 1.5 10.6 4.5 11.4 4.4 1.8 2.2 4.8 4.0 9.7 4.8 2.8 2.1 1.8 3.1 2.2 1.7 6.9 2.5 1.9 2.8 0.7 7.5 2.8 2.1 2.4 5.3 4.9 2.5 12.9 12.1 1.3 2.8 2.4 5.3 5.4 4.5 8.4 4.1 2.4 3.4 5.8 0.8 0.1 13.0 20.5 0.1 1.7 3.1 0.2 0.7 0.6 1.2 6.4 10.8 4.0 6.9 2.1 0.3 8.4 0.7 0.6 1.4 7.7 10.8 0.6 4.1 6.3 14.4 13.2 6.7 7.6 1.7 9.5 34.0 0.1 7.9 1.1 3.0 0.1 0.0 6.1 0.1 3.3 1.7 0.1 0.2 6.6 12.6 7.2 0.0 0.0 9.6 2.8 1.5 0.1 0.3 11.5 36.9 1.6 1.4 0.4 2.4 0.3 0.1 0.8 3.0 13.3 5.9 27.4 11.2 4.1 1.2 11.3 1.0 1.0 1.7 1.1 7.7 2.0 1.6 1.2 10.7 1.8 13.9 3.0 3.6 4.5 1.7 1.9 1.9 1.9 1.8 2.2 2.8 2.1 2.5 2.5 2.8 2.4 23.8 0.0 17.5 0.0 3.1 1.7 1.5 6.6 5.2 0.0 2.9 2.0 1.4 11.5 6.4 1.8 0.0 0.7 1.8 0.2 0.0 15.9 0.6 5.7 9.6 20.1 0.0 4.8 0.1 14.0 0.8 10.2 26.5 10.3 13.3 0.4 15.4 3.1 9.2 0.0 0.1 0.4 4.1 16.6 1.8 1.0 3.1 14.1 0.0 4.7 11.2 0.7 2.1 0.5 0.1 21.7 1.2 1.2 0.9 0.4 3.2 0.9 4.4 0.0 0.0 1.1 2.7 0.6 0.2 11.3 2.3 0.5 3.0 8.5 1.2 9.1 CARD8 "CARDINAL, Dakar, KIAA0955, NDPP, TUCAN" ENSG00000105483 "Caspase recruitment domain family member 8" Q9Y2G2 19 48180770-48255946 "Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 115.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 114.4;HUVEC TERT2: 154.6;NB-4: 131.8;TIME: 148.6" "HPA042071, HPA043513" Supported Supported Nucleoplasm NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA042071: AB_2677831, HPA043513: AB_2678522" "unprognostic (3.96e-2)" "unprognostic (1.92e-1)" "unprognostic (7.84e-2)" "unprognostic (1.48e-1)" "unprognostic (3.30e-2)" "unprognostic (1.58e-2)" "unprognostic (6.95e-2)" "unprognostic (2.18e-2)" "unprognostic (9.19e-2)" "unprognostic (7.30e-2)" "unprognostic (3.79e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (1.63e-8)" "unprognostic (1.78e-1)" "unprognostic (1.69e-1)" "unprognostic (9.19e-2)" "prognostic favorable (1.72e-5)" 27.7 8.7 7.8 29.1 9.6 23.7 17.1 9.0 8.7 13.1 11.0 11.2 12.7 10.9 7.8 8.2 8.9 14.4 12.9 7.5 9.3 8.9 12.4 19.1 38.2 10.8 9.6 8.5 11.5 9.7 5.8 23.6 10.6 7.1 11.9 5.4 8.0 7.8 16.3 7.7 14.7 15.9 9.8 38.8 13.8 10.6 11.5 31.3 13.0 20.1 36.9 15.4 7.7 11.1 13.4 31.1 28.1 9.1 10.0 15.3 10.9 12.4 15.6 19.0 29.1 10.8 20.1 28.7 15.8 11.9 12.8 8.2 16.9 9.2 17.1 43.8 14.9 114.4 17.0 21.6 11.8 59.2 87.3 11.2 7.0 10.8 11.7 16.5 154.6 28.6 16.8 32.5 15.6 9.5 24.4 131.8 7.1 27.9 7.8 40.9 13.4 7.1 11.2 17.1 9.7 14.6 20.4 14.2 18.5 13.6 8.9 52.2 148.6 11.3 14.3 5.0 21.2 28.9 78.3 18.0 5.2 42.1 21.2 104.9 45.8 76.8 29.2 63.5 33.8 30.7 29.4 34.4 39.9 31.2 27.4 29.5 167.3 28.1 68.2 27.9 45.0 32.2 7.8 9.6 9.0 8.7 7.5 9.3 10.8 9.6 10.6 9.8 11.5 11.1 115.7 3.2 29.2 11.4 38.9 9.3 4.9 6.5 2.2 8.9 11.4 8.3 9.9 12.8 8.6 12.9 12.5 26.9 50.9 5.1 5.9 7.9 25.3 5.8 10.3 68.6 5.4 36.2 2.0 10.8 11.2 12.1 7.1 6.7 34.1 25.6 73.5 25.9 41.9 6.7 2.7 7.4 6.1 79.5 30.9 59.3 7.8 61.6 21.4 55.3 47.6 4.2 79.3 13.6 17.3 11.2 6.7 7.9 40.1 3.5 9.7 11.7 9.3 3.4 6.6 11.2 11.3 19.6 14.2 6.5 7.1 15.5 55.6 8.6 7.0 3.4 CAVIN2 "cavin-2, PS-p68, SDPR, SDR" ENSG00000168497 "Caveolae associated protein 2" O95810 2 191834310-191847088 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 1296.7;Alveolar cells type 1: 413.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 49.0;neutrophil: 24.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 49.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 162.3;HEL: 119.8;HUVEC TERT2: 362.3;LHCN-M2: 561.1;TIME: 148.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039325, HPA062122" Enhanced Enhanced "Plasma membrane,Cytosol" Yes No 88000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA039325: AB_10805473, HPA062122: AB_2684688" "unprognostic (6.85e-3)" "unprognostic (1.37e-1)" "unprognostic (1.24e-1)" "unprognostic (4.47e-2)" "unprognostic (2.83e-1)" "unprognostic (1.46e-1)" "unprognostic (3.19e-2)" "unprognostic (6.14e-2)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (2.90e-1)" "prognostic favorable (8.45e-5)" "prognostic unfavorable (3.69e-4)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (4.39e-3)" 164.9 25.1 17.9 13.0 20.1 6.5 60.9 16.9 20.2 56.8 13.1 69.4 11.5 38.9 13.2 48.2 53.9 51.8 96.7 15.1 16.5 25.9 31.2 93.9 15.3 19.5 17.3 53.0 22.5 12.9 7.1 34.0 19.5 30.2 24.9 1.1 7.1 30.0 32.3 6.9 21.1 58.1 15.9 111.9 15.0 4.3 22.3 4.1 78.3 59.9 5.6 42.7 19.5 17.0 0.0 20.2 6.8 0.1 1.0 3.4 0.1 4.1 3.5 0.8 1.5 0.0 0.0 0.1 24.8 162.3 0.0 3.4 0.0 31.8 2.3 0.1 0.0 119.8 1.4 45.6 43.6 0.0 0.0 8.4 20.5 3.4 9.6 2.2 362.3 0.0 43.9 0.0 561.1 0.0 0.0 0.1 0.1 0.0 1.0 0.0 32.3 0.2 41.7 0.0 0.0 0.1 0.0 0.0 0.0 9.1 0.0 0.1 148.9 0.0 12.4 7.4 0.0 0.0 0.0 0.1 0.0 1.0 0.0 49.0 2.4 1.2 0.2 0.8 0.3 0.1 0.0 0.0 2.3 0.3 0.2 0.0 24.3 1.3 1.5 3.1 0.5 121.3 17.9 20.1 16.9 20.2 15.1 16.5 19.5 17.3 19.5 15.9 22.3 17.0 1296.7 413.5 76.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.7 15.6 0.0 0.0 81.7 0.0 0.0 0.2 2.6 0.0 5.9 1.6 0.0 0.4 5.4 164.5 0.0 0.0 0.0 0.2 0.2 15.0 0.0 0.6 185.4 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.7 29.2 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.1 1.5 16.4 0.0 0.0 CBWD6 CBWD7 ENSG00000215126 "COBW domain containing 6" Q4V339 9 41131306-41199261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 39.4;Excitatory neurons: 24.9;Inhibitory neurons: 20.2;Langerhans cells: 30.0;Oligodendrocyte precursor cells: 18.6;Suprabasal keratinocytes: 42.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 17.3;PC-3: 26.8;TIME: 16.6" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (9.48e-2)" "unprognostic (6.02e-2)" "unprognostic (1.62e-2)" "unprognostic (1.91e-2)" "unprognostic (1.30e-2)" "unprognostic (6.28e-2)" "unprognostic (5.92e-2)" "unprognostic (3.71e-2)" "unprognostic (2.07e-2)" "unprognostic (1.12e-1)" "unprognostic (4.24e-2)" "unprognostic (1.09e-1)" "unprognostic (2.28e-4)" "unprognostic (5.65e-2)" "unprognostic (1.65e-1)" "unprognostic (1.01e-2)" "unprognostic (9.94e-4)" 2.0 5.3 1.8 0.7 1.8 2.2 2.1 1.8 3.4 1.0 2.5 1.9 1.1 1.2 0.2 2.9 0.9 1.5 3.4 1.8 2.1 3.4 7.2 2.0 0.3 1.9 1.9 1.6 3.4 0.1 2.7 0.2 2.2 1.7 0.1 0.9 2.5 1.9 3.6 1.5 1.9 0.3 1.9 2.1 2.2 1.9 2.0 0.1 2.2 0.0 0.5 1.1 1.9 1.8 2.0 0.5 0.9 0.2 0.9 2.4 1.6 11.0 12.4 12.6 0.0 4.3 1.2 2.7 0.5 9.0 0.5 1.8 15.9 0.3 0.4 2.8 10.6 0.7 6.4 2.9 0.1 3.4 1.0 0.2 1.5 8.4 10.1 0.9 9.7 0.8 1.4 1.5 17.3 1.8 5.1 0.7 2.3 4.5 26.8 1.2 10.8 3.6 11.5 0.5 0.7 1.2 2.7 0.8 1.1 2.2 0.9 1.5 16.6 0.2 1.0 0.3 1.2 4.9 0.8 13.5 1.5 1.0 1.2 1.6 4.1 1.7 0.6 5.0 0.9 3.5 2.9 2.3 2.3 1.2 1.8 2.2 0.6 0.4 7.0 2.7 1.3 2.4 1.8 1.8 1.8 3.4 1.8 2.1 1.9 1.9 2.2 1.9 2.0 1.8 2.0 3.2 8.9 5.2 1.3 39.4 0.0 11.0 0.0 0.0 5.1 2.7 0.0 0.0 7.5 5.5 0.0 5.2 1.4 0.0 3.9 4.3 0.0 1.5 0.9 1.4 0.0 0.0 24.9 4.9 5.2 1.4 0.0 1.4 8.8 2.2 0.0 0.0 3.0 0.0 20.2 0.0 8.2 0.0 30.0 0.0 0.0 1.4 14.2 5.6 1.6 0.0 0.0 18.6 8.1 4.4 0.0 0.0 1.4 0.0 0.0 8.8 7.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 42.9 6.3 2.8 1.4 0.0 0.0 CCDC178 "C18orf34, FLJ44050" ENSG00000166960 "Coiled-coil domain containing 178" Q5BJE1 18 32937402-33441101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.9;testis: 15.2" "Cell type enhanced" "Detected in some" "Adipocytes: 29.2;Early spermatids: 89.0;Late spermatids: 76.8;Spermatocytes: 49.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "HUVEC TERT2: 5.1;U-87 MG: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.15e-2)" "unprognostic (2.66e-1)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (9.88e-2)" "unprognostic (2.58e-1)" "unprognostic (2.75e-1)" "unprognostic (2.58e-3)" "unprognostic (2.92e-1)" "unprognostic (5.95e-4)" "unprognostic (4.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.94e-4)" "unprognostic (2.86e-1)" "unprognostic (1.42e-3)" "unprognostic (9.03e-3)" 10.9 0.3 0.2 0.2 0.3 0.0 7.8 0.0 0.4 2.7 0.1 0.8 0.5 1.3 2.2 0.6 1.5 2.5 0.5 0.2 0.3 2.8 0.1 0.7 0.2 0.4 0.6 4.0 0.1 0.0 0.6 0.0 0.2 3.5 0.5 0.1 0.5 2.0 0.3 0.7 0.6 1.5 0.4 7.6 0.6 15.2 0.1 0.1 0.8 0.0 0.6 2.1 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.3 0.4 0.6 0.2 0.4 0.1 0.2 29.2 0.0 0.0 0.3 0.0 0.4 0.4 0.0 2.2 0.0 0.1 0.4 0.3 0.0 0.0 1.8 0.0 0.0 0.1 0.0 9.8 0.0 89.0 0.6 0.3 12.8 0.0 0.0 7.9 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.0 0.0 76.8 1.8 0.2 0.0 2.8 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.7 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.2 49.4 16.3 0.1 0.3 0.0 0.0 6.1 0.0 0.0 CCDC190 "C1orf110, MGC48998" ENSG00000185860 "Coiled-coil domain containing 190" Q86UF4 1 162824458-162868815 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 2.3;choroid plexus: 1.0;esophagus: 3.3;lung: 1.8" "Cell type enriched" "Detected in some" 4 "Respiratory ciliated cells: 26.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.9;hTERT-RPE1: 4.8;HUVEC TERT2: 4.8;LHCN-M2: 7.3;TIME: 16.7;U-2197: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028579, HPA028584, HPA028592" Uncertain Approved Vesicles NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA028579: AB_10610978, HPA028584: AB_10599423, HPA028592: AB_10601001" "unprognostic (4.29e-1)" "unprognostic (8.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-2)" "unprognostic (8.33e-3)" "unprognostic (3.04e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (7.41e-5)" "unprognostic (2.64e-1)" "unprognostic (1.52e-1)" "unprognostic (5.26e-1)" "unprognostic (1.70e-1)" 0.1 0.1 0.9 0.0 1.0 0.0 0.0 0.3 1.0 0.1 1.0 0.0 0.0 0.1 0.3 3.3 0.5 0.4 0.5 1.4 2.1 0.0 0.0 1.8 0.0 1.6 2.1 0.0 0.0 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.5 0.0 0.1 0.3 2.3 0.0 0.1 0.1 0.4 0.1 0.0 2.3 0.1 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.2 0.3 0.2 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 3.9 2.4 4.8 4.8 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.4 0.0 8.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.3 1.0 1.4 2.1 1.6 2.1 1.0 0.5 2.3 2.3 0.0 0.0 0.5 0.0 0.2 0.0 0.7 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 2.5 0.6 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 26.2 0.0 0.0 0.4 0.5 0.1 0.2 5.8 0.0 0.0 0.0 0.0 0.0 0.5 CCDC25 FLJ10853 ENSG00000147419 "Coiled-coil domain containing 25" Q86WR0 8 27733316-27772653 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023256 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Golgi apparatus" Cytosol "HPA023256: AB_2072067" "unprognostic (1.43e-1)" "unprognostic (5.48e-2)" "unprognostic (3.10e-3)" "unprognostic (1.60e-1)" "unprognostic (4.39e-1)" "unprognostic (6.62e-3)" "unprognostic (2.34e-1)" "unprognostic (2.48e-2)" "unprognostic (1.51e-1)" "unprognostic (8.49e-3)" "unprognostic (3.50e-1)" "unprognostic (2.69e-2)" "prognostic favorable (1.11e-7)" "unprognostic (3.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" 14.0 20.9 10.1 11.8 11.4 4.9 17.4 10.5 17.1 10.1 7.3 14.3 35.5 10.4 14.3 14.2 12.9 11.9 12.2 9.9 11.3 22.5 32.3 8.8 14.0 11.1 10.5 10.8 16.3 18.3 7.5 10.6 11.5 11.6 15.7 11.1 13.5 12.0 28.4 10.3 30.8 10.3 11.3 10.5 20.0 10.9 11.9 11.4 18.8 15.2 14.2 11.7 9.4 13.0 50.1 27.9 25.8 24.7 22.8 33.0 17.2 41.0 39.5 24.7 24.0 11.2 17.9 53.6 27.7 20.9 21.2 23.1 23.6 40.0 35.5 20.3 16.4 66.9 23.1 19.3 36.9 23.8 20.8 37.1 25.9 27.1 37.6 28.7 54.0 33.7 32.2 24.6 27.8 19.2 55.3 19.9 37.9 49.4 14.8 18.7 44.4 28.8 32.3 26.7 15.1 41.7 27.5 21.0 42.8 19.0 24.0 13.1 44.6 22.5 33.4 38.9 21.7 24.5 33.8 19.5 35.0 30.8 23.8 20.3 8.9 6.6 15.2 12.6 17.8 19.8 19.6 16.1 11.6 15.5 18.3 19.3 3.2 14.3 13.4 18.1 23.2 10.4 10.1 11.4 10.5 17.1 9.9 11.3 11.1 10.5 11.5 11.3 11.9 13.0 47.5 25.6 38.9 12.4 34.8 21.4 39.6 46.5 55.2 42.6 57.3 61.6 62.5 60.1 44.5 53.3 12.5 77.6 31.2 61.6 109.5 76.9 183.1 46.8 51.0 54.2 26.5 46.7 30.5 134.6 56.0 49.3 63.2 33.3 63.9 39.3 55.0 144.5 44.7 55.5 21.9 58.6 46.8 33.5 27.2 162.9 47.2 27.4 37.4 12.2 44.4 60.2 35.0 12.1 17.7 83.7 51.1 47.4 40.7 55.2 182.1 128.6 53.7 38.9 46.0 44.4 49.1 91.1 59.6 56.7 22.3 42.4 38.7 88.1 71.2 36.0 CCDC68 SE57-1 ENSG00000166510 "Coiled-coil domain containing 68" Q9H2F9 18 54901509-54959461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.8;placenta: 32.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 95.2;Early spermatids: 95.4;Pancreatic endocrine cells: 87.9;Paneth cells: 68.7;Proximal enterocytes: 61.1" "Cancer enhanced" "Detected in many" "stomach cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 10.8;HHSteC: 13.6;HSkMC: 14.9;RT4: 10.5;TIME: 28.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA040865, HPA048197" Supported Approved "Golgi apparatus,Cytosol" No NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Cytosol "HPA040865: AB_2677176, HPA048197: AB_2680310" "unprognostic (1.36e-2)" "prognostic unfavorable (4.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.38e-2)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (2.65e-2)" "unprognostic (6.29e-2)" "unprognostic (2.71e-1)" "unprognostic (1.16e-1)" "unprognostic (1.15e-3)" "unprognostic (1.13e-1)" "prognostic favorable (5.28e-4)" "unprognostic (1.77e-2)" "unprognostic (9.71e-2)" "unprognostic (6.12e-2)" "unprognostic (2.38e-1)" 5.5 3.8 1.6 4.1 1.5 0.4 3.4 1.4 2.7 4.2 2.3 18.9 20.2 3.3 0.8 1.8 2.4 5.1 5.7 1.5 3.6 2.8 9.5 13.0 0.8 2.0 2.3 15.7 2.8 0.8 3.6 32.4 2.0 4.2 18.2 0.6 1.8 1.3 1.5 0.9 24.8 2.7 1.2 7.2 14.3 8.8 3.3 0.6 2.6 4.4 1.3 2.3 1.8 1.3 10.8 3.3 0.0 0.0 3.0 8.3 0.0 0.3 4.2 0.6 0.7 5.9 6.2 0.0 7.6 0.0 0.1 0.1 0.7 6.8 0.5 0.0 1.6 0.8 3.6 1.2 13.6 0.0 0.0 14.9 0.0 3.2 0.1 0.0 4.9 0.0 0.0 0.1 0.4 0.8 0.0 0.2 0.0 7.6 3.6 0.3 0.0 0.3 1.2 10.5 0.1 2.5 3.3 1.0 0.1 1.2 0.0 0.0 28.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.6 1.5 1.4 2.7 1.5 3.6 2.0 2.3 2.0 1.2 3.3 1.3 38.5 19.2 10.3 0.3 1.0 0.3 7.4 4.8 1.2 0.1 2.0 1.9 5.5 10.0 13.3 1.8 0.0 2.3 0.3 95.2 1.9 7.2 95.4 15.0 2.5 40.8 6.0 3.6 5.7 35.6 2.7 9.6 38.2 27.1 8.8 2.6 37.5 7.0 0.4 0.0 0.5 21.8 8.2 3.2 1.3 36.7 3.4 0.6 0.0 12.2 1.0 3.3 1.0 0.0 0.1 87.9 68.7 0.7 0.0 32.4 61.1 5.3 4.2 0.2 6.6 0.9 3.0 1.2 2.2 1.1 0.0 6.0 0.4 3.8 20.2 6.4 CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 1156.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "HUVEC TERT2: 92.1" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" 411.9 102.7 0.4 6.4 0.3 3.3 400.7 0.2 1.7 192.0 2.8 66.6 2.9 198.0 59.3 62.0 233.5 69.3 98.6 0.3 0.3 69.2 82.6 66.4 49.0 0.5 0.3 44.1 22.6 12.4 39.5 0.9 0.7 97.4 9.8 0.0 61.9 49.5 55.9 93.3 50.5 94.3 0.4 632.7 67.5 16.0 0.4 34.4 123.9 24.5 28.2 116.8 177.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.7 0.3 0.3 0.5 0.3 0.7 0.4 0.4 0.3 136.5 0.0 8.2 0.0 2.2 1.9 0.1 0.0 3.4 0.0 0.6 1.1 0.2 18.6 0.6 0.0 0.0 0.0 0.1 2.0 0.0 0.0 24.2 0.4 0.3 203.8 0.0 26.7 0.0 0.0 0.0 9.4 0.0 0.2 1.3 0.0 1156.5 11.0 0.3 0.0 0.0 1.0 0.0 58.8 3.1 63.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 2.3 1.1 2.6 0.0 0.0 0.3 2.3 0.0 0.0 2.0 1.4 0.0 1.8 0.1 0.6 0.2 CCN2 "CTGF, IGFBP8" ENSG00000118523 "Cellular communication network factor 2" P29279 6 131948176-131951372 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cell adhesion, DNA synthesis" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 101.2;Cardiomyocytes: 38.7;Extravillous trophoblasts: 47.1;Fibroblasts: 261.8;Smooth muscle cells: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 8.1" "Lineage enriched" "Detected in single" 81 "B-cells: 8.1" "Cell line enhanced" "Detected in many" "EFO-21: 1605.0;HUVEC TERT2: 1377.0;TIME: 2874.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005123, HPA031074, HPA031075" Approved Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" No No 1010000 5900000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "CAB005123: AB_638805, HPA031074: AB_10599618, HPA031075: AB_10611248" "unprognostic (2.87e-1)" "unprognostic (1.43e-1)" "unprognostic (4.41e-2)" "unprognostic (5.68e-2)" "unprognostic (9.79e-2)" "unprognostic (1.82e-2)" "unprognostic (3.38e-1)" "unprognostic (4.96e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.27e-3)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.62e-1)" "unprognostic (1.77e-2)" "unprognostic (3.84e-3)" 265.9 107.5 18.9 168.0 18.8 2.0 206.4 16.3 34.0 531.0 31.5 148.8 43.7 418.5 34.4 271.9 243.8 441.4 371.8 25.8 14.2 235.7 82.9 226.3 73.6 18.8 32.1 77.0 194.0 43.0 44.8 198.2 20.2 364.6 136.1 2.4 138.2 154.3 51.8 155.1 151.2 576.3 14.2 569.1 182.6 24.7 20.8 49.5 464.7 61.9 14.9 324.0 102.5 18.2 4.6 7.5 126.8 3.7 279.9 158.5 1.8 373.1 178.2 226.8 119.4 0.2 12.2 0.6 1605.0 482.7 185.0 6.2 4.2 26.4 211.3 2.5 3.5 0.2 55.7 137.3 109.6 0.3 0.5 232.2 5.9 163.9 40.2 340.7 1377.0 0.0 0.4 0.3 650.8 2.5 0.5 1.2 61.8 41.3 21.7 32.6 6.0 0.7 81.9 0.4 0.5 0.8 38.3 62.2 18.3 308.5 6.1 3.1 2874.4 311.6 242.4 397.8 694.0 11.5 1.7 4.1 42.5 0.7 399.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.9 18.8 16.3 34.0 25.8 14.2 18.8 32.1 20.2 14.2 20.8 18.2 101.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 0.0 0.0 0.0 17.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 47.1 261.8 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.4 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 CD109 "CPAMD7, DKFZp762L1111, FLJ38569" ENSG00000156535 "CD109 molecule" Q6YHK3 6 73695785-73828316 "CD markers, Plasma proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "parathyroid gland: 330.4" "Cell type enhanced" "Detected in many" "Adipocytes: 65.3;Basal respiratory cells: 62.8;Hofbauer cells: 45.0;Squamous epithelial cells: 51.4;Suprabasal keratinocytes: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 206.4;BJ hTERT+: 126.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008992, HPA015723" Enhanced Supported "Plasma membrane,Cytosol" NA NA 180000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA008992: , HPA015723: AB_2732415" "unprognostic (2.28e-1)" "unprognostic (1.03e-1)" "unprognostic (7.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.17e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-3)" "unprognostic (1.23e-3)" "unprognostic (7.49e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-3)" "unprognostic (8.81e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (7.96e-5)" "unprognostic (9.50e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (4.68e-4)" 8.6 1.1 2.3 2.4 2.5 2.8 5.5 2.1 2.1 9.9 0.7 6.9 1.3 12.5 5.6 10.2 3.2 4.1 5.8 2.0 4.0 7.0 1.1 6.6 1.0 3.2 3.6 0.7 0.5 330.4 0.4 6.5 3.5 3.6 2.9 0.2 3.4 2.5 1.2 18.9 2.2 12.6 3.7 2.1 1.1 1.8 2.5 3.1 1.3 3.3 2.2 4.5 7.4 3.1 35.6 29.4 1.5 0.1 48.2 206.4 0.0 30.5 126.0 9.0 18.4 0.1 20.2 0.0 19.7 63.5 19.5 96.5 3.5 60.9 12.1 8.5 5.5 11.5 21.0 5.8 10.1 0.0 0.3 60.7 52.4 18.6 68.7 34.2 71.6 3.9 0.0 0.2 45.0 0.8 0.8 0.0 2.4 0.3 18.9 2.6 8.4 40.6 4.8 3.6 0.0 0.1 68.6 0.7 30.8 1.3 0.8 5.8 68.7 96.8 10.1 17.2 28.5 0.7 17.9 0.1 40.3 0.1 89.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 2.3 2.5 2.1 2.1 2.0 4.0 3.2 3.6 3.5 3.7 2.5 3.1 65.3 3.2 1.7 39.8 1.1 41.4 8.4 62.8 35.9 0.3 2.2 2.2 13.0 0.0 16.3 0.0 0.0 0.4 1.2 0.1 1.9 0.1 23.4 10.8 10.5 38.0 0.0 7.6 4.0 0.0 0.5 25.0 0.5 15.0 2.5 0.0 21.0 0.6 45.0 0.0 3.3 0.1 4.1 2.7 28.5 21.0 0.6 13.5 23.2 19.7 3.3 0.0 0.0 1.5 1.0 0.4 0.0 0.0 1.7 10.8 0.0 23.5 16.0 0.2 0.0 7.4 13.2 1.0 3.5 51.4 43.8 1.4 4.6 1.4 0.2 7.2 CD59 "16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20" ENSG00000085063 "CD59 molecule (CD59 blood group)" P13987 11 33703010-33736479 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1445.2;Prostatic glandular cells: 1678.0;Urothelial cells: 1531.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 3747.5;U-2197: 3049.9" "CAB001448, HPA026494" Supported Uncertain "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 58000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus, Vesicles" "CAB001448: AB_563604, HPA026494: AB_1846321" "unprognostic (2.07e-2)" "prognostic unfavorable (3.81e-5)" "unprognostic (7.40e-2)" "unprognostic (1.14e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (3.10e-5)" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (4.47e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.92e-5)" "unprognostic (1.66e-2)" "prognostic favorable (1.39e-10)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (3.09e-1)" 517.4 248.3 284.5 209.6 310.8 198.8 555.9 329.0 365.1 305.5 542.2 255.1 120.7 290.7 971.7 478.9 368.1 475.3 608.3 288.2 359.7 577.4 339.8 553.5 148.8 327.9 340.2 228.5 353.6 706.1 250.3 485.6 340.9 256.8 271.4 130.7 693.6 443.2 529.3 282.8 167.9 380.0 330.5 131.8 422.7 127.7 337.0 167.7 308.1 915.0 288.6 550.5 325.5 315.6 297.2 278.4 77.6 212.0 1697.1 1314.9 46.8 1765.7 1778.5 408.9 451.9 129.7 822.1 23.9 291.5 1802.5 475.5 314.0 141.0 1589.9 561.1 475.5 218.2 31.3 846.7 193.1 483.2 183.4 94.8 631.8 387.2 343.3 1550.6 1104.9 2475.5 109.3 207.9 585.9 2575.4 282.7 79.9 70.3 43.5 541.8 1421.8 30.1 232.1 227.8 1304.4 510.0 54.3 79.5 576.2 243.7 298.2 218.0 187.5 18.1 3747.5 838.6 235.5 3049.9 595.9 273.8 558.8 30.4 734.2 1.3 1556.9 164.9 22.3 209.6 50.9 7.9 64.8 63.9 104.9 56.6 95.4 59.6 68.2 41.4 134.3 92.5 4.8 49.9 298.2 53.5 284.5 310.8 329.0 365.1 288.2 359.7 327.9 340.2 340.9 330.5 337.0 315.6 728.0 272.4 247.2 32.3 39.1 286.0 1103.2 951.4 82.0 51.3 434.9 270.0 315.5 444.7 569.7 242.8 33.3 553.5 29.2 344.6 164.4 1445.2 129.4 94.3 91.6 792.6 166.6 206.0 25.1 618.3 407.2 303.5 109.6 115.6 139.4 88.2 585.0 185.7 486.7 47.1 29.9 112.8 722.2 139.4 374.2 61.6 237.3 88.2 1270.0 54.4 161.7 198.3 26.8 32.6 22.2 1195.7 392.2 204.7 149.7 1678.0 41.7 208.2 1042.5 56.2 276.1 159.1 410.7 130.6 31.2 83.7 284.4 836.6 52.4 139.5 104.9 1531.0 CD9 "BA2, MIC3, MRP-1, P24, TSPAN29" ENSG00000010278 "CD9 molecule" P21926 12 6199715-6238271 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2822.0;Ionocytes: 4461.6;Urothelial cells: 2594.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "basophil: 1957.3;eosinophil: 1156.4" "Lineage enriched" "Detected in all" 32 "granulocytes: 1957.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 1521.6;RT4: 1126.8;TIME: 2266.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002490 Supported Supported "Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB002490: AB_563643" "unprognostic (1.38e-1)" "unprognostic (6.36e-3)" "unprognostic (8.27e-3)" "unprognostic (6.98e-3)" "unprognostic (3.89e-1)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (2.90e-1)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.30e-1)" "prognostic favorable (6.49e-5)" "unprognostic (6.10e-2)" "unprognostic (1.77e-1)" "prognostic favorable (8.93e-5)" "unprognostic (9.26e-2)" 204.4 287.8 116.9 96.5 162.9 17.3 298.9 139.8 193.3 399.5 157.3 496.9 127.2 242.4 270.9 1000.2 242.3 102.4 267.5 124.3 132.3 294.2 79.4 403.0 37.4 165.8 141.0 69.0 93.4 881.8 98.1 85.4 160.2 488.5 466.2 32.6 614.5 456.4 74.4 455.3 211.2 197.0 139.2 69.5 178.2 26.4 146.5 66.1 338.0 116.6 289.4 373.1 566.4 207.1 417.6 173.7 3.5 108.7 167.7 170.8 150.1 241.1 477.8 80.8 121.9 128.5 1521.6 1.4 59.2 51.4 239.0 885.6 92.7 475.5 62.7 21.5 63.1 2.0 117.1 26.6 71.3 1.1 497.0 0.6 347.0 147.3 126.0 225.3 976.3 28.9 19.3 1.7 51.5 578.6 1.8 45.4 136.0 504.3 175.7 4.1 290.1 529.7 802.1 1126.8 0.5 34.0 240.9 195.8 215.8 789.0 91.1 42.1 2266.0 8.6 214.6 8.8 29.5 1.7 1.3 63.2 137.2 1.0 221.7 1957.3 61.1 1156.4 1.3 23.6 2.2 5.5 1.4 1.6 10.2 20.5 4.2 11.5 30.9 2.6 0.6 3.7 0.4 71.7 116.9 162.9 139.8 193.3 124.3 132.3 165.8 141.0 160.2 139.2 146.5 207.1 250.0 794.9 403.1 35.6 27.8 1037.8 1864.4 2822.0 804.1 4.9 433.5 379.5 20.9 84.4 1403.7 1075.9 0.0 21.5 8.7 929.9 137.0 599.1 3.0 457.8 66.8 496.5 172.9 10.5 0.4 178.2 271.0 356.9 60.6 722.6 653.4 42.3 522.6 43.1 618.0 0.0 0.6 744.8 4461.6 35.2 685.3 13.1 32.0 253.4 940.9 11.2 151.7 375.1 2.1 56.3 169.5 352.9 896.4 70.7 59.3 1576.4 330.0 21.7 1409.8 14.7 664.0 322.6 397.5 7.3 74.1 1214.3 1279.8 54.0 77.8 838.5 761.1 2594.9 CDC42 "CDC42Hs, G25K" ENSG00000070831 "Cell division cycle 42" P60953 1 22025511-22101360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004360, HPA069590" Approved Supported "Microtubules,Cytokinetic bridge" Yes No 2700000 "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Microtubules, Cytokinetic bridge" "CAB004360: AB_627233, HPA069590: AB_2732138" "unprognostic (9.40e-2)" "unprognostic (1.37e-1)" "unprognostic (9.45e-3)" "unprognostic (5.11e-2)" "unprognostic (1.73e-1)" "unprognostic (9.72e-2)" "prognostic unfavorable (5.28e-5)" "unprognostic (1.09e-1)" "unprognostic (7.92e-3)" "unprognostic (1.86e-2)" "unprognostic (3.90e-2)" "unprognostic (9.41e-2)" "unprognostic (9.72e-3)" "unprognostic (2.71e-1)" "unprognostic (3.88e-2)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" 177.4 116.1 91.7 160.2 96.5 402.9 142.7 100.1 113.8 128.6 98.4 198.2 142.3 131.3 99.8 162.3 124.8 131.7 117.0 95.2 108.8 158.8 153.5 154.1 167.9 115.5 103.7 105.9 82.5 128.4 59.6 170.3 108.4 108.3 185.4 95.9 103.8 107.5 119.9 132.0 156.9 175.0 107.4 157.5 159.9 64.2 102.2 157.7 110.6 120.9 216.8 194.8 114.9 127.1 341.9 146.4 272.2 222.0 295.0 306.4 274.2 347.3 318.8 365.5 336.2 178.0 374.5 253.1 272.8 416.7 136.2 210.7 241.1 369.3 431.1 332.4 180.1 438.1 184.5 225.4 259.1 388.5 350.5 285.6 396.6 341.0 195.2 234.7 535.6 157.8 250.8 273.4 430.2 135.6 242.9 307.5 170.2 242.9 179.3 199.6 297.6 243.3 316.2 301.3 183.4 175.8 293.4 228.7 263.4 296.3 242.3 219.1 466.3 265.3 265.2 349.3 207.8 148.6 355.9 305.8 234.5 419.3 277.6 244.3 200.6 255.1 142.4 282.3 144.3 108.0 152.0 146.7 162.3 103.4 109.5 143.5 308.3 145.0 352.2 107.2 157.4 244.8 91.7 96.5 100.1 113.8 95.2 108.8 115.5 103.7 108.4 107.4 102.2 127.1 502.1 60.9 51.8 20.9 301.0 450.6 385.5 266.0 136.1 119.1 281.1 179.6 86.9 231.6 168.0 312.6 18.8 349.6 470.1 434.9 375.6 441.3 38.0 350.5 356.5 307.7 300.4 243.0 58.5 441.9 499.6 225.2 152.4 425.8 163.6 138.2 277.0 230.9 439.2 106.0 71.0 315.4 187.2 585.4 875.2 41.3 157.8 443.4 423.4 53.4 654.9 102.5 286.3 41.7 72.9 570.5 369.7 177.1 192.9 323.1 283.1 578.2 176.2 65.2 236.7 174.2 308.3 155.3 116.2 176.6 556.6 551.6 379.2 178.6 286.7 469.6 CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318474 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 320.3;Excitatory neurons: 447.6;Inhibitory neurons: 479.0;Oligodendrocyte precursor cells: 444.3;Oligodendrocytes: 671.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Intermediate filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Intermediate filaments" "CAB070414: AB_11156796, HPA071252: AB_2686374" "unprognostic (3.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (4.88e-2)" "unprognostic (2.87e-2)" "unprognostic (7.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-2)" "unprognostic (1.21e-2)" 15.6 12.5 26.3 5.5 32.4 3.5 12.2 33.5 30.0 15.8 12.2 21.2 14.7 15.0 7.7 10.1 12.6 13.7 16.4 24.9 25.2 17.3 14.7 12.3 2.0 25.7 26.8 14.0 13.1 19.7 14.6 12.7 27.0 15.8 10.3 23.7 7.6 14.9 11.4 6.3 12.9 14.5 19.8 6.6 22.4 24.4 29.7 2.2 8.1 13.6 1.8 23.0 11.3 37.0 22.6 21.1 21.9 10.4 21.5 26.4 7.7 25.4 35.7 17.2 17.9 17.1 50.1 0.1 26.6 42.4 13.0 10.3 16.3 14.2 20.9 0.1 13.2 17.4 25.5 6.7 24.3 14.1 7.5 18.6 17.9 27.8 27.8 21.3 58.0 13.6 45.1 0.1 28.2 6.2 0.4 2.5 18.0 29.3 20.0 0.0 37.0 0.1 27.7 43.1 15.7 22.9 43.0 17.8 24.8 13.4 23.1 0.8 59.0 31.3 16.2 36.1 33.9 0.1 0.1 0.1 41.4 0.0 42.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 26.3 32.4 33.5 30.0 24.9 25.2 25.7 26.8 27.0 19.8 29.7 37.0 82.6 41.7 35.7 320.3 0.8 11.7 26.0 15.9 12.0 97.7 14.0 12.8 59.9 30.0 38.9 44.1 118.9 5.9 1.8 49.3 13.7 26.0 128.0 18.7 45.1 68.4 26.4 45.6 447.6 41.1 7.3 44.4 92.8 25.7 7.0 21.5 47.8 28.9 3.7 223.8 479.0 30.5 22.4 4.4 9.9 132.3 44.1 6.4 16.0 180.8 5.9 33.4 0.0 444.3 671.8 65.1 74.0 85.4 1.8 30.1 50.7 41.3 24.8 66.9 78.9 64.0 68.4 45.6 57.7 8.0 8.0 1.4 1.3 23.4 34.4 43.1 CDC42BPB "KIAA1124, MRCKB" ENSG00000198752 "CDC42 binding protein kinase beta" Q9Y5S2 14 102932380-103057549 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022821 Approved NA NA 12000 "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA022821: AB_1846376" "unprognostic (6.73e-2)" "unprognostic (2.19e-2)" "unprognostic (6.99e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (2.90e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "unprognostic (3.46e-2)" "unprognostic (2.28e-1)" "prognostic favorable (8.67e-10)" "unprognostic (2.11e-1)" "unprognostic (1.86e-1)" "unprognostic (8.59e-2)" "unprognostic (7.56e-2)" 38.7 31.3 42.7 17.8 42.5 3.6 31.2 31.2 40.2 33.5 21.0 35.8 30.2 38.0 17.9 37.8 31.3 29.5 36.3 44.3 36.4 32.3 28.9 32.9 9.8 38.6 40.2 33.4 33.1 34.2 32.5 29.5 35.7 28.7 20.2 24.1 27.9 30.4 27.2 33.0 34.9 32.3 38.5 22.2 32.0 25.2 40.8 8.6 29.6 24.2 12.6 35.0 33.2 46.1 42.8 83.8 52.7 38.7 57.3 65.1 53.0 47.9 50.3 49.7 45.4 28.8 49.0 0.0 51.1 93.7 37.7 53.0 54.9 57.2 52.3 52.2 24.8 23.4 68.0 29.0 62.2 0.2 24.1 56.7 57.6 51.0 48.5 52.2 97.7 9.8 19.3 11.7 48.3 89.2 0.4 5.4 25.3 66.5 68.4 0.2 44.3 1.2 63.1 82.6 38.2 41.6 85.1 31.6 35.8 55.7 48.7 14.9 125.3 47.3 31.6 105.8 45.3 15.1 17.4 12.4 53.2 5.2 46.9 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.7 42.5 31.2 40.2 44.3 36.4 38.6 40.2 35.7 38.5 40.8 46.1 57.1 57.7 35.8 37.5 7.8 14.5 16.5 14.5 17.6 45.8 19.1 15.4 28.8 28.6 27.4 55.2 33.3 12.6 0.5 35.4 3.9 29.8 14.2 35.8 55.0 46.3 25.2 11.0 40.3 21.8 11.1 25.7 32.1 59.4 13.3 37.8 36.0 20.5 12.8 57.2 33.1 16.1 30.5 13.5 14.7 7.9 32.3 21.7 12.4 31.9 11.1 29.3 0.0 31.7 74.6 44.2 15.4 55.3 3.5 26.1 28.2 15.4 28.1 42.3 6.6 38.6 29.3 15.5 17.0 27.2 18.3 16.8 3.2 37.3 27.5 32.4 CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 311.9;Endothelial cells: 206.1;Hepatic stellate cells: 185.6;Late spermatids: 84.6;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 752.5;TIME: 655.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" 84.5 13.8 16.3 14.9 15.9 0.2 71.4 15.1 16.6 16.2 11.3 16.8 7.9 19.9 8.6 12.4 17.1 29.7 84.4 13.8 14.6 19.1 24.0 95.0 13.1 16.7 16.6 8.1 7.7 10.3 7.4 235.9 17.9 11.6 10.2 1.3 12.0 9.1 41.8 16.7 17.0 27.8 15.5 20.4 13.3 10.5 22.6 5.2 37.5 58.9 7.9 22.1 14.2 15.5 0.5 0.6 4.6 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 119.8 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 752.5 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 15.7 0.0 2.4 0.0 0.1 655.1 0.0 0.9 0.1 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 15.9 15.1 16.6 13.8 14.6 16.7 16.6 17.9 15.5 22.6 15.5 311.9 0.0 6.2 1.3 0.7 4.1 0.0 0.0 1.8 0.0 1.0 2.7 17.9 5.7 0.6 1.8 0.0 6.6 0.5 0.0 0.0 0.2 33.5 0.5 0.6 206.1 0.0 10.7 0.1 0.0 48.9 7.1 0.0 1.3 3.8 0.0 185.6 1.7 2.3 0.0 0.1 0.0 0.0 35.7 6.3 84.6 6.2 1.2 12.4 28.1 0.1 0.3 0.0 0.5 0.1 0.0 0.0 2.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.4 10.9 0.3 0.3 3.0 80.7 1.5 3.0 0.1 0.2 CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400480 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 101.5;Oligodendrocytes: 259.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 134.8;TIME: 160.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA015325: AB_1855090" "unprognostic (4.35e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.50e-1)" "unprognostic (4.96e-3)" "unprognostic (5.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.23e-2)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.09e-6)" "unprognostic (4.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.92e-2)" "unprognostic (1.70e-2)" 21.4 11.2 26.3 18.9 45.9 48.1 18.4 23.0 34.7 13.2 8.3 17.0 11.9 26.2 9.1 14.6 13.9 16.2 11.4 36.7 28.6 11.6 16.3 20.6 21.7 23.2 23.0 15.7 10.5 10.6 8.0 31.8 23.0 14.0 12.2 19.3 8.7 11.1 8.8 11.0 11.5 29.5 27.4 21.8 10.5 26.6 28.5 24.8 11.6 12.3 22.2 17.1 12.8 54.0 15.4 12.5 32.5 8.9 15.9 41.2 24.1 34.8 46.9 29.1 27.2 7.7 8.8 22.7 23.0 24.5 15.6 13.8 19.8 20.9 39.5 24.9 15.5 32.7 8.5 10.9 34.4 17.9 18.4 30.0 21.3 43.0 77.1 51.8 134.8 18.9 24.7 18.1 66.8 9.5 17.0 28.1 14.4 7.6 22.8 29.2 18.0 19.8 35.1 12.7 17.1 11.7 19.9 18.4 25.9 24.7 14.0 15.7 160.5 25.6 10.0 13.8 18.7 26.0 21.1 24.1 9.6 7.6 19.2 66.7 6.4 17.1 22.2 9.3 24.0 17.5 17.9 25.1 10.0 16.6 25.0 21.7 23.2 31.4 9.0 7.3 15.8 16.6 26.3 45.9 23.0 34.7 36.7 28.6 23.2 23.0 23.0 27.4 28.5 54.0 58.1 16.0 6.5 54.5 37.3 26.8 10.7 8.6 19.4 11.8 13.8 9.8 11.9 7.2 10.3 9.2 16.7 12.0 64.4 7.2 0.0 4.9 3.3 17.6 10.0 51.7 15.0 17.9 101.5 3.6 27.9 24.0 21.4 17.2 18.3 8.9 34.2 10.8 12.1 5.0 59.2 7.9 4.1 14.5 20.7 4.1 9.9 16.7 17.8 64.6 8.6 22.6 32.0 52.3 259.2 7.4 3.4 9.4 64.7 12.5 6.5 8.6 15.4 9.6 6.6 22.7 22.0 8.8 21.6 24.2 25.9 13.7 63.2 10.7 6.0 15.1 CDYL2 FLJ38866 ENSG00000166446 "Chromodomain Y like 2" Q8N8U2 16 80597907-80804598 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 69.6;Glandular and luminal cells: 34.3;Late spermatids: 26.4;Microglial cells: 30.9;Oligodendrocyte precursor cells: 27.6" "Cancer enhanced" "Detected in all" "prostate cancer: 9.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 1.0;non-classical monocyte: 4.0" "Lineage enriched" "Detected in single" 8 "monocytes: 4.0" "Cell line enhanced" "Detected in many" "HDLM-2: 15.9;HUVEC TERT2: 22.7;MCF7: 20.2;TIME: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041016 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA041016: AB_10794183" "unprognostic (8.63e-2)" "unprognostic (7.37e-2)" "unprognostic (2.93e-3)" "prognostic favorable (6.13e-4)" "unprognostic (1.48e-1)" "unprognostic (4.38e-2)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (1.02e-1)" "unprognostic (2.40e-1)" "unprognostic (2.30e-1)" "unprognostic (1.54e-1)" "unprognostic (1.22e-1)" "unprognostic (4.33e-2)" "unprognostic (9.11e-2)" "unprognostic (2.12e-1)" "unprognostic (3.69e-3)" 2.9 1.3 4.1 3.4 6.1 5.6 3.1 12.5 9.5 4.2 0.0 1.2 3.2 2.3 1.9 1.9 0.8 1.6 1.0 5.9 5.8 3.6 1.8 2.1 3.7 2.2 23.6 0.3 1.2 2.6 0.8 11.0 7.5 9.8 1.4 1.1 2.5 6.1 0.4 0.8 2.9 2.9 1.0 2.2 1.8 11.1 7.4 1.7 1.3 0.7 3.4 3.4 1.2 4.9 0.0 0.0 0.3 0.0 5.3 5.3 4.6 5.6 3.7 1.5 0.4 0.2 2.8 0.5 1.8 3.4 0.0 0.1 0.2 5.6 0.8 15.9 3.1 2.0 8.3 0.2 0.2 0.2 0.2 1.7 2.1 2.9 2.6 8.1 22.7 1.8 0.0 0.2 0.8 20.2 0.0 0.1 1.7 0.2 6.1 0.0 0.0 0.0 8.8 7.1 1.4 0.0 0.7 4.6 0.0 1.3 4.5 3.3 33.9 0.1 9.9 0.0 1.4 0.0 0.0 0.0 3.4 4.3 0.1 0.3 0.1 0.5 0.1 1.0 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.1 0.0 0.0 4.0 0.0 0.2 0.1 4.1 6.1 12.5 9.5 5.9 5.8 2.2 23.6 7.5 1.0 7.4 4.9 5.2 3.2 1.7 15.0 1.7 2.8 2.7 0.3 0.6 0.6 7.7 2.7 1.6 2.8 1.0 3.7 0.0 11.8 2.7 0.7 3.9 2.4 13.1 7.4 7.2 7.0 1.2 4.4 69.6 4.2 5.9 3.1 0.5 34.3 0.0 3.1 6.1 4.5 2.3 0.0 21.8 2.6 0.0 9.1 1.7 26.4 2.8 4.3 0.0 30.9 16.2 0.7 0.0 27.6 2.0 2.1 0.5 4.5 1.1 8.3 4.8 5.9 0.2 0.4 0.0 0.1 3.8 4.7 10.2 0.7 1.1 16.3 4.9 4.3 2.0 2.9 CEACAM19 CEAL1 ENSG00000186567 "CEA cell adhesion molecule 19" Q7Z692 19 44662278-44684359 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.9;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 12.2;RPTEC TERT1: 15.8;TIME: 20.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.1" "HPA014462, HPA052865" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Nucleoli, Mitochondria" Nucleoplasm "HPA014462: AB_2669006, HPA052865: AB_2681976" "unprognostic (2.91e-1)" "unprognostic (5.29e-3)" "unprognostic (6.96e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-2)" "unprognostic (8.43e-2)" "unprognostic (5.22e-2)" "unprognostic (1.15e-2)" "unprognostic (9.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.77e-1)" "unprognostic (3.26e-9)" "unprognostic (8.01e-3)" "unprognostic (9.62e-2)" "unprognostic (1.31e-1)" "unprognostic (2.70e-1)" 3.9 5.6 3.7 1.3 3.7 1.5 3.8 4.9 5.1 7.0 3.5 4.7 3.0 5.2 1.7 5.1 6.8 2.4 11.7 4.0 3.8 9.4 8.2 8.2 1.1 2.8 3.0 6.6 8.9 1.5 7.0 2.2 2.7 7.8 3.4 2.4 5.7 3.1 13.8 12.4 3.8 3.1 1.9 3.5 4.6 5.7 3.7 0.9 6.5 3.4 2.2 4.2 8.7 4.7 5.1 10.3 1.5 1.0 3.5 4.0 3.8 2.8 4.2 0.9 1.8 0.4 1.1 0.1 1.0 3.8 1.0 6.2 2.6 1.1 0.8 1.5 5.8 0.1 6.7 1.7 3.6 0.2 1.0 1.3 10.0 2.6 6.1 12.2 2.4 0.7 0.3 0.3 1.4 1.2 0.0 0.6 0.9 1.4 1.1 0.0 1.8 0.2 15.8 1.2 1.9 0.5 1.1 1.1 0.9 1.4 1.4 0.3 20.9 0.4 6.8 1.5 0.9 0.1 0.3 0.0 0.5 2.0 1.7 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.7 3.7 4.9 5.1 4.0 3.8 2.8 3.0 2.7 1.9 3.7 4.7 3.6 3.2 2.2 2.0 0.0 2.0 0.9 2.1 1.2 2.9 1.9 1.5 4.5 1.5 2.4 0.0 0.0 0.2 0.1 2.1 0.0 1.6 3.8 0.9 0.9 4.1 1.8 0.0 7.9 3.3 0.2 1.0 3.6 2.4 0.0 0.8 4.6 2.6 0.3 0.0 6.1 2.3 4.1 0.6 0.8 1.9 3.1 0.5 0.0 1.9 0.4 0.3 1.0 2.0 2.4 4.5 2.6 2.6 0.0 1.8 1.2 0.4 1.8 0.6 0.0 8.8 1.7 3.1 0.9 1.2 6.0 0.0 0.2 1.6 2.5 0.9 CEP164 "KIAA1052, NPHP15" ENSG00000110274 "Centrosomal protein 164" Q9UPV0 11 117314557-117413266 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, DNA damage, DNA repair, Mitosis" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 454.5;Early spermatids: 241.0;Late spermatids: 291.7;Rod photoreceptor cells: 268.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037605, HPA037606" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Centrosome" "HPA037605: AB_10672908, HPA037606: AB_10672498" "unprognostic (1.92e-1)" "unprognostic (8.99e-2)" "unprognostic (7.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.47e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (1.90e-1)" "prognostic favorable (5.93e-4)" "unprognostic (6.54e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "unprognostic (2.13e-1)" "unprognostic (7.93e-2)" 7.0 5.8 6.7 9.7 8.2 7.3 6.8 10.8 8.0 10.5 11.5 7.3 4.2 10.8 8.1 8.6 11.4 8.4 4.3 5.5 7.9 5.1 7.3 6.7 7.6 8.2 7.5 11.9 26.3 5.6 11.1 4.6 8.1 6.9 5.1 26.0 5.7 5.8 3.1 8.0 6.2 10.3 4.9 8.5 5.8 23.9 9.2 7.7 8.4 1.3 8.5 7.1 7.5 14.0 13.2 18.0 13.0 25.9 12.8 21.7 4.2 25.6 14.3 18.0 17.5 22.4 20.8 25.9 18.1 15.9 17.7 17.1 14.6 15.0 15.3 25.8 12.0 7.8 18.9 7.1 18.9 11.3 16.8 15.2 12.6 27.3 26.5 16.1 23.6 12.6 21.7 16.4 14.4 11.2 10.6 10.2 9.2 8.5 19.4 14.0 15.5 10.1 7.9 11.3 15.1 21.8 20.3 12.2 14.4 14.4 16.9 13.2 25.7 21.3 13.2 20.7 23.8 5.8 7.7 15.2 10.3 12.6 14.5 96.2 34.3 23.4 35.4 30.9 22.9 38.8 44.3 40.4 13.9 41.0 41.4 32.6 82.5 29.6 42.0 49.4 52.6 10.8 6.7 8.2 10.8 8.0 5.5 7.9 8.2 7.5 8.1 4.9 9.2 14.0 21.0 6.4 13.1 28.1 15.4 7.6 10.3 13.2 10.8 97.7 14.5 23.6 5.8 15.7 10.3 11.0 454.5 4.5 14.3 9.0 1.9 11.1 241.0 26.5 30.3 18.3 15.5 8.0 19.0 14.7 6.8 17.2 17.9 14.7 19.6 17.6 13.2 9.0 12.9 74.0 26.3 10.2 10.2 11.7 11.4 291.7 23.9 14.5 5.4 8.4 21.2 23.4 15.5 21.6 28.7 11.7 5.8 17.0 11.0 9.8 5.4 6.2 31.6 268.7 0.0 30.3 21.4 37.6 17.2 11.4 8.1 2.2 16.4 45.0 11.9 5.6 CETP BPIFF ENSG00000087237 "Cholesteryl ester transfer protein" P11597 16 56961923-56983845 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 33.5;liver: 43.0;lymphoid tissue: 59.6;placenta: 36.2" "Group enriched" "Detected in some" 6 "Adipocytes: 48.6;Hepatic stellate cells: 75.0;Kupffer cells: 142.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.3;plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 2.3;HUVEC TERT2: 4.7;TIME: 2.8" "Secreted to blood" NA NA 2470000000 360000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.52e-2)" "unprognostic (4.17e-3)" "unprognostic (2.48e-1)" "unprognostic (1.00e-1)" "unprognostic (4.01e-3)" "unprognostic (4.03e-3)" "unprognostic (3.56e-2)" "unprognostic (1.41e-1)" "unprognostic (3.05e-3)" "unprognostic (4.92e-3)" "unprognostic (7.17e-3)" "unprognostic (2.62e-1)" "unprognostic (7.62e-2)" "unprognostic (2.20e-2)" "unprognostic (4.08e-2)" "unprognostic (7.34e-2)" "unprognostic (9.97e-2)" 33.5 2.0 0.7 3.8 0.7 5.7 6.6 0.7 1.4 0.3 0.7 0.6 0.9 0.7 0.0 0.3 0.3 4.0 0.7 0.6 0.8 3.7 43.0 2.8 43.3 1.1 0.8 0.3 0.5 1.8 3.1 36.2 0.9 0.3 0.5 0.0 0.7 0.5 0.3 0.4 1.9 0.8 0.8 59.6 0.4 0.3 0.9 2.3 5.2 0.3 7.6 1.5 0.1 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.2 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.8 0.1 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.3 0.1 0.0 0.0 0.1 1.8 2.3 3.2 0.0 1.2 0.7 0.7 0.7 1.4 0.6 0.8 1.1 0.8 0.9 0.8 0.9 0.8 48.6 0.0 1.8 0.0 1.5 0.5 0.0 0.0 0.0 0.1 0.4 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 13.4 0.0 5.3 0.1 0.9 0.4 0.2 0.0 0.1 0.0 0.0 75.0 1.3 3.1 0.0 0.1 0.2 0.0 142.0 1.2 0.7 0.0 2.1 0.0 0.0 1.4 0.0 1.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.1 0.6 0.0 0.4 0.0 0.4 1.3 0.0 0.0 CFAP54 "C12orf55, C12orf63, FLJ31514, FLJ44112" ENSG00000188596 "Cilia and flagella associated protein 54" Q96N23 12 96489571-96875555 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.7;choroid plexus: 30.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;Alveolar cells type 2: 80.1;Club cells: 42.7;Endometrial ciliated cells: 65.8;granulocytes: 37.8;Oligodendrocytes: 47.7;Respiratory ciliated cells: 106.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 7.7;TIME: 9.4" "Low region specificity" "Detected in many" HPA039897 Enhanced Approved Microtubules,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Microtubules Cytosol "HPA039897: AB_10674427" "unprognostic (1.87e-4)" "unprognostic (3.63e-2)" "unprognostic (8.07e-2)" "unprognostic (7.89e-2)" "unprognostic (4.66e-2)" "unprognostic (5.55e-2)" "unprognostic (2.75e-2)" "unprognostic (2.91e-2)" "unprognostic (6.16e-2)" "unprognostic (8.40e-2)" "unprognostic (2.86e-1)" "unprognostic (2.36e-1)" "unprognostic (3.55e-5)" "unprognostic (2.72e-2)" "unprognostic (3.35e-1)" "unprognostic (3.26e-2)" "unprognostic (8.00e-2)" 0.8 0.7 5.6 1.3 8.1 2.7 0.9 9.2 10.3 0.6 30.7 0.7 1.8 1.6 1.6 0.7 5.0 0.8 0.5 7.0 4.6 0.9 0.9 1.4 1.2 14.6 14.7 1.0 0.2 0.6 1.0 0.7 7.3 0.9 1.1 6.2 0.8 0.6 1.3 1.6 1.2 0.6 8.5 1.5 1.0 5.4 7.0 0.5 1.3 0.2 1.1 0.4 0.1 12.4 1.4 0.6 0.8 1.1 0.4 0.6 0.9 0.7 0.2 0.2 0.4 0.6 1.9 1.0 1.6 0.4 0.9 1.0 0.3 0.3 0.3 2.0 0.6 0.9 2.3 0.7 0.1 1.5 1.5 0.2 0.3 1.1 0.5 1.8 7.7 0.9 0.6 3.5 0.8 0.7 1.2 1.5 1.7 0.6 1.0 1.2 1.1 1.3 2.2 1.3 1.6 1.2 0.8 0.7 1.0 0.9 2.1 0.7 9.4 1.7 2.2 1.8 1.5 4.2 2.1 0.6 1.3 0.9 1.3 2.4 0.7 0.6 0.7 0.6 0.5 0.7 0.5 0.6 0.3 1.1 0.6 0.6 1.3 0.7 0.7 0.6 0.4 0.1 5.6 8.1 9.2 10.3 7.0 4.6 14.6 14.7 7.3 8.5 7.0 12.4 2.1 70.5 80.1 27.1 2.6 0.0 0.3 0.0 0.0 3.9 0.3 0.6 1.0 1.5 42.7 0.0 22.9 0.3 2.2 0.0 0.0 0.2 33.2 65.8 2.9 6.8 1.2 1.3 21.9 0.0 0.3 6.4 0.5 1.9 37.8 0.6 0.4 0.0 0.2 0.0 3.9 0.0 0.0 0.8 0.0 15.4 0.3 3.2 0.0 1.9 0.1 8.1 0.0 4.0 47.7 0.3 0.1 0.0 5.0 0.5 0.0 0.3 106.4 7.8 0.0 1.7 0.5 16.8 7.0 0.0 0.0 0.0 4.2 1.9 0.1 0.3 CFLAR "c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT" ENSG00000003402 "CASP8 and FADD like apoptosis regulator" O15519 2 201116154-201176687 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 609.9;Urothelial cells: 521.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 392.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 392.6" "Cell line enhanced" "Detected in all" "U-266/70: 214.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019044, CAB022157, CAB025216" Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB022157: , CAB025216: , HPA019044: AB_10696204" "unprognostic (4.61e-2)" "unprognostic (5.32e-2)" "unprognostic (2.49e-1)" "unprognostic (1.44e-1)" "unprognostic (2.95e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.46e-2)" "unprognostic (9.01e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (3.08e-2)" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (7.83e-2)" "unprognostic (9.13e-2)" "unprognostic (6.84e-2)" "unprognostic (2.24e-2)" 122.4 50.6 38.8 103.9 40.9 247.6 83.1 54.1 47.4 57.0 75.6 86.0 59.2 57.9 60.6 68.0 66.6 71.6 184.8 39.4 32.7 57.5 59.2 174.6 91.1 46.5 40.5 38.3 40.7 31.8 29.4 94.0 42.1 65.6 56.4 12.4 58.0 63.2 222.8 51.0 64.8 58.8 36.6 98.1 56.5 25.3 51.9 54.1 78.8 89.2 107.3 78.7 61.7 46.1 21.5 42.9 30.0 17.9 92.3 71.0 37.5 53.6 92.1 34.3 41.6 50.4 78.4 5.8 49.6 62.5 41.6 15.5 9.8 40.3 53.9 160.7 29.9 32.3 38.4 82.2 63.6 24.2 102.2 76.8 39.6 58.2 50.3 41.7 176.7 7.3 110.8 131.2 63.1 17.9 11.3 96.3 10.2 17.2 32.7 11.7 7.2 46.5 42.5 44.0 6.6 11.8 35.7 31.2 43.2 19.6 22.1 44.8 193.6 71.0 29.5 26.7 26.1 214.6 76.2 35.9 50.6 19.5 36.3 91.8 60.3 70.3 54.4 61.8 48.4 25.6 46.5 52.1 33.4 20.9 29.5 38.3 392.6 45.2 68.5 23.0 60.7 42.0 38.8 40.9 54.1 47.4 39.4 32.7 46.5 40.5 42.1 36.6 51.9 46.1 191.3 451.9 234.9 30.3 126.4 54.8 229.6 164.9 29.0 10.9 38.9 30.0 205.8 102.9 206.7 69.9 31.3 77.2 166.2 132.5 74.3 148.8 83.3 202.8 75.0 261.0 95.1 59.1 6.9 72.5 34.8 89.5 73.4 219.2 81.6 93.4 201.0 97.5 68.6 13.5 16.8 76.8 40.7 123.2 609.9 44.8 51.9 278.0 97.8 146.1 247.0 23.4 276.0 29.7 56.8 166.4 155.6 49.7 317.8 386.0 116.7 101.5 276.1 30.7 39.5 113.2 77.9 14.4 12.2 33.2 86.1 70.1 168.3 56.1 50.9 521.3 CGNL1 "FLJ14957, JACOP, KIAA1749, PCING" ENSG00000128849 "Cingulin like 1" Q0VF96 15 57375967-57550717 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 87.2;Astrocytes: 79.7;Hepatic stellate cells: 58.5;Hepatocytes: 65.5;Microglial cells: 156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 52.7;SuSa: 37.6;TIME: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013500, HPA056911, HPA069214" Enhanced Supported "Nuclear bodies,Cell Junctions" No No "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Cell Junctions" "Nuclear bodies" "CAB013500: , HPA056911: AB_2683274, HPA069214: AB_2686102" "unprognostic (1.04e-2)" "unprognostic (2.42e-1)" "unprognostic (1.52e-2)" "prognostic favorable (3.55e-4)" "unprognostic (3.22e-1)" "unprognostic (1.51e-3)" "prognostic favorable (5.58e-4)" "unprognostic (4.32e-2)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (4.05e-2)" "unprognostic (1.91e-2)" "prognostic favorable (1.37e-6)" "unprognostic (2.26e-2)" "unprognostic (3.39e-1)" "unprognostic (1.88e-3)" "unprognostic (1.18e-2)" 5.0 11.5 23.6 1.5 23.0 0.0 19.8 19.8 18.5 32.0 47.2 3.2 1.2 17.8 4.4 11.0 8.9 2.8 20.1 18.6 24.2 68.3 36.0 21.0 1.1 28.9 28.2 5.8 18.6 9.6 4.1 28.8 27.7 28.7 2.3 12.3 32.3 16.2 0.7 11.5 2.5 10.8 20.0 0.4 15.5 6.6 29.9 4.6 19.8 1.9 3.2 8.9 20.2 15.7 0.0 1.3 13.1 0.0 0.0 0.0 0.2 0.2 2.9 1.1 2.4 8.4 0.1 0.0 11.4 1.7 1.9 0.0 6.2 0.1 1.8 0.1 1.0 0.1 0.1 5.7 0.2 0.1 0.0 0.4 0.4 1.3 0.0 4.4 52.7 0.5 0.0 0.0 2.1 2.4 0.0 0.2 6.5 3.7 0.6 0.1 6.6 0.3 4.4 0.0 0.3 0.7 0.0 5.1 0.0 37.6 0.5 0.6 32.5 0.0 3.3 0.1 1.9 0.0 0.0 0.0 0.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.6 23.0 19.8 18.5 18.6 24.2 28.9 28.2 27.7 20.0 29.9 15.7 3.9 51.3 87.2 79.7 0.2 4.6 13.4 5.1 4.6 0.4 27.4 27.1 21.0 10.0 11.7 22.0 0.0 1.0 1.6 0.9 41.1 9.9 3.0 11.0 9.4 21.8 13.1 2.7 0.7 13.2 1.0 17.1 11.2 11.8 1.3 3.5 58.5 65.5 0.3 0.0 1.9 3.7 18.3 1.6 4.9 18.1 19.9 0.9 7.2 156.4 0.6 43.7 0.0 11.1 1.5 4.3 1.2 27.8 0.0 18.6 0.2 39.4 2.2 1.4 0.0 6.6 2.3 0.6 0.6 0.8 2.4 1.4 1.2 0.6 2.2 7.0 CLDN11 "OSP, OTM" ENSG00000013297 "Claudin 11" O75508 3 170418868-170454733 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 130.1;ovary: 95.4;testis: 116.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 56.4;Leydig cells: 105.3;Oligodendrocytes: 394.5;Peritubular cells: 67.7" "Cancer enhanced" "Detected in many" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 141.3;ASC TERT1: 174.2;EFO-21: 91.8;HUVEC TERT2: 162.2;TIME: 252.1" "Region enriched" "Detected in all" 5 "white matter: 2084.8" "CAB009789, HPA013166, HPA013657" Enhanced Supported "Lipid droplets,Cell Junctions" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" "Cell Junctions" "Lipid droplets" "CAB009789: AB_639330, HPA013166: AB_1854821, HPA013657: " "prognostic favorable (6.31e-4)" "unprognostic (3.18e-1)" "unprognostic (2.32e-2)" "unprognostic (5.28e-4)" "unprognostic (3.45e-2)" "unprognostic (4.60e-1)" "unprognostic (5.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.52e-1)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" "unprognostic (5.48e-2)" "unprognostic (8.70e-11)" "unprognostic (2.50e-3)" "unprognostic (1.93e-1)" "unprognostic (6.68e-3)" "unprognostic (2.29e-1)" 29.9 5.4 18.8 0.0 51.7 0.0 15.3 48.7 36.5 6.7 4.4 7.6 0.1 8.1 1.5 5.1 18.0 8.7 7.8 22.7 34.6 6.4 2.2 4.8 0.2 130.1 44.2 95.4 0.8 0.0 20.9 1.2 88.6 11.2 0.3 0.2 5.2 1.0 1.5 6.5 6.6 0.4 52.5 1.2 3.1 116.9 47.4 0.0 1.8 0.7 0.1 13.2 13.2 94.6 0.0 0.0 0.1 0.0 141.3 174.2 0.0 1.2 8.5 11.0 19.6 0.0 19.2 0.0 91.8 14.2 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 10.6 42.8 0.0 0.0 61.0 0.0 60.9 0.0 0.4 162.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 4.6 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 51.7 48.7 36.5 22.7 34.6 130.1 44.2 88.6 52.5 47.4 94.6 16.4 0.0 0.6 2.3 0.4 14.4 15.6 1.0 0.0 0.5 5.7 27.7 1.4 1.5 0.1 1.8 0.0 0.9 0.8 0.3 0.0 0.1 8.3 0.5 0.2 37.3 0.0 2.7 1.5 0.0 1.6 56.4 0.0 0.6 0.0 27.2 49.2 1.1 0.9 0.0 2.8 0.0 0.0 1.2 23.8 24.3 105.3 1.1 14.2 24.4 0.0 0.4 0.0 3.5 394.5 0.7 0.0 67.7 0.0 15.4 0.2 0.2 0.2 0.1 0.0 2.9 6.6 11.6 4.1 1.0 10.2 0.8 0.6 1.6 0.1 2.0 CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 439.7;breast: 420.9;lung: 398.7" "Group enriched" "Detected in many" 10 "Adipocytes: 2644.3;Endothelial cells: 775.2;Hepatic stellate cells: 701.4" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 18.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 18.8" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 85.4;SCLC-21H: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" 439.7 16.2 124.1 6.1 101.0 0.3 420.9 111.7 127.4 70.2 205.2 75.9 9.2 86.1 3.0 54.4 83.1 6.5 138.3 93.8 103.3 45.5 16.9 398.7 9.6 124.5 114.0 36.4 20.7 1.5 16.9 12.5 127.8 50.2 3.6 2.0 36.0 3.5 101.6 95.9 71.0 6.4 109.2 44.8 41.4 10.5 160.7 1.8 122.5 14.9 2.2 103.7 75.9 107.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.1 0.1 0.2 1.1 0.0 0.0 0.0 0.0 85.4 0.1 0.7 0.2 0.1 0.0 0.1 0.5 0.2 0.0 0.2 0.9 0.7 0.1 0.0 0.0 53.0 0.3 0.0 0.0 0.0 0.0 0.4 0.2 7.1 0.1 1.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.2 18.8 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 4.6 0.2 5.8 0.0 0.1 0.1 0.0 26.9 124.1 101.0 111.7 127.4 93.8 103.3 124.5 114.0 127.8 109.2 160.7 107.4 2644.3 3.2 7.7 0.7 2.4 32.4 1.1 0.1 3.4 1.8 5.9 7.6 14.8 2.8 0.6 7.3 0.0 0.3 4.2 0.0 0.0 0.7 5.0 8.1 0.7 775.2 2.4 8.0 0.0 0.8 0.1 12.5 0.0 1.0 1.3 0.3 701.4 2.7 0.8 0.0 0.1 0.2 4.1 17.0 33.3 5.5 5.3 46.2 14.2 129.3 0.7 2.4 1.0 0.5 0.3 0.0 0.0 0.7 2.8 4.0 0.0 0.0 0.3 7.3 0.0 61.7 12.1 1.1 1.9 1.2 30.5 0.0 4.6 25.0 0.0 6.7 CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Adipocytes: 396.6;Endothelial cells: 272.8;Hepatic stellate cells: 567.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 83.7;HUVEC TERT2: 451.8;TIME: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 4100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum, Golgi apparatus" "HPA039468: AB_2676524, HPA048119: AB_2680270" "unprognostic (4.02e-1)" "unprognostic (4.26e-2)" "unprognostic (4.20e-3)" "unprognostic (9.44e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.13e-6)" "unprognostic (2.55e-3)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (5.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (4.97e-2)" "unprognostic (5.28e-2)" 67.1 9.5 13.6 7.9 13.4 0.1 50.6 13.8 15.2 24.8 10.9 15.2 10.1 31.2 7.6 11.1 22.6 19.0 65.1 11.5 13.3 15.9 9.4 55.5 6.6 15.0 13.9 9.5 7.8 10.5 6.1 25.0 15.4 14.5 7.2 0.8 13.6 9.8 33.2 15.8 18.8 19.8 13.1 16.7 13.8 3.5 14.9 4.6 31.4 43.3 4.2 19.2 16.8 15.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 451.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 13.4 13.8 15.2 11.5 13.3 15.0 13.9 15.4 13.1 14.9 15.6 396.6 0.0 3.2 0.0 0.9 3.4 0.2 0.0 1.8 0.1 1.5 2.5 6.4 1.5 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.1 0.2 0.5 272.8 0.0 0.0 0.4 0.2 0.1 31.0 0.0 0.3 1.3 0.1 567.2 2.1 0.4 0.0 0.2 0.0 0.0 6.4 3.1 1.0 0.6 1.1 5.4 15.0 0.0 0.2 0.0 4.0 2.9 0.0 0.0 0.4 1.4 0.2 0.0 0.0 0.0 0.5 0.0 14.1 7.5 1.6 0.9 0.9 3.1 0.1 1.3 6.7 0.0 0.3 CLTA Lca ENSG00000122705 "Clathrin light chain A" P09496 9 36190856-36304781 "Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1299.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002665, HPA050918, HPA054667" Enhanced Enhanced Vesicles,Endosomes,Lysosomes NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Vesicles, Endosomes, Lysosomes" "CAB002665: , HPA050918: AB_2681273, HPA054667: AB_2682565" "prognostic favorable (5.64e-4)" "unprognostic (7.62e-2)" "unprognostic (9.22e-2)" "unprognostic (8.45e-3)" "unprognostic (1.71e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (9.46e-5)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (1.92e-3)" "unprognostic (7.27e-2)" "unprognostic (2.15e-1)" "unprognostic (1.23e-3)" "unprognostic (5.92e-2)" "unprognostic (1.56e-1)" "prognostic favorable (1.01e-4)" "unprognostic (4.98e-2)" 172.8 174.2 131.6 80.8 139.1 67.2 165.6 144.7 165.1 170.9 137.5 163.3 107.9 165.6 100.7 207.1 158.9 64.4 98.1 133.3 143.8 236.0 146.8 146.2 84.1 145.1 138.5 205.6 164.3 104.3 139.3 124.4 151.4 145.0 108.6 84.8 162.8 71.2 87.7 163.2 136.0 84.9 141.6 153.0 161.4 108.5 141.7 85.2 160.1 51.5 93.4 150.9 158.4 151.5 326.3 257.2 188.4 146.3 270.0 269.8 302.6 328.5 248.2 258.1 301.5 194.2 143.9 243.8 177.0 220.9 460.7 136.2 238.8 228.2 238.4 166.0 193.1 187.5 255.0 199.8 359.4 201.0 166.5 297.3 250.5 297.4 234.3 241.0 329.6 129.3 166.0 126.4 399.0 113.3 182.2 254.8 301.8 218.8 360.3 173.3 124.8 142.1 353.7 229.1 146.1 245.3 137.3 160.0 289.4 220.2 146.9 244.2 418.4 209.4 234.0 240.3 347.9 83.0 208.9 259.5 256.9 278.0 188.9 142.2 221.7 115.4 97.1 239.6 101.9 121.0 104.9 100.2 222.6 119.6 92.9 82.0 86.7 96.2 191.8 192.2 162.9 209.4 131.6 139.1 144.7 165.1 133.3 143.8 145.1 138.5 151.4 141.6 141.7 151.5 291.5 128.2 143.9 14.4 105.9 197.3 274.3 374.3 169.0 139.4 274.0 315.0 51.5 217.3 247.4 180.3 60.5 958.0 140.1 349.3 463.7 480.5 51.9 241.5 174.3 244.0 183.8 154.8 28.5 335.6 469.1 187.5 142.2 182.7 73.5 198.4 312.7 170.6 903.7 92.5 30.4 350.5 248.2 391.7 172.0 97.6 262.9 249.3 195.7 20.6 343.5 282.8 117.4 16.1 49.0 465.2 426.4 215.5 97.7 320.5 411.5 651.7 304.7 127.3 177.5 170.0 310.4 288.0 216.8 210.9 193.2 1299.5 103.7 281.6 380.0 360.4 COL13A1 ENSG00000197467 "Collagen type XIII alpha 1 chain" Q5TAT6 10 69801880-69964275 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Osteogenesis" "Developmental protein, Heparin-binding" "Congenital myasthenic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 30.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 10.1;granulocytes: 20.3;Melanocytes: 5.4;Microglial cells: 6.5;NK-cells: 9.2;Smooth muscle cells: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 63.6;BJ hTERT+: 61.6;hTERT-RPE1: 83.7;HUVEC TERT2: 102.2;PC-3: 93.1;TIME: 137.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA050392 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA050392: AB_2681110" "unprognostic (2.79e-2)" "unprognostic (2.82e-3)" "unprognostic (1.38e-1)" "unprognostic (3.86e-1)" "unprognostic (4.67e-4)" "unprognostic (3.13e-1)" "unprognostic (1.69e-1)" "unprognostic (7.43e-2)" "unprognostic (6.16e-3)" "unprognostic (1.22e-1)" "unprognostic (2.60e-1)" "unprognostic (2.53e-2)" "unprognostic (1.36e-5)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (1.52e-2)" "unprognostic (3.93e-2)" 1.2 1.9 1.5 2.6 1.7 0.3 2.0 9.5 3.3 5.7 1.9 4.6 2.9 1.8 30.4 1.9 2.8 2.4 3.4 1.4 1.5 2.0 0.8 10.9 0.9 1.6 1.6 0.9 2.1 0.8 3.7 1.7 1.8 13.6 3.4 0.0 0.7 8.0 0.9 5.2 3.8 2.9 1.6 8.0 6.2 0.7 1.7 0.3 1.5 1.4 0.8 3.8 1.8 1.5 1.5 0.6 22.1 0.0 0.1 4.3 0.1 63.6 61.6 10.9 5.5 0.0 1.4 0.2 10.5 30.1 1.0 2.3 0.0 0.2 18.9 0.0 1.6 0.0 0.0 0.0 2.9 0.0 0.1 9.8 0.1 27.5 9.0 83.7 102.2 0.0 0.0 0.1 10.4 0.4 0.0 0.2 5.3 0.0 93.1 0.1 0.0 10.3 0.4 0.0 2.4 0.0 0.0 0.2 3.4 0.9 0.0 0.2 137.4 0.3 17.1 5.7 45.7 13.4 0.0 0.1 37.2 0.1 51.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.5 1.7 9.5 3.3 1.4 1.5 1.6 1.6 1.8 1.6 1.7 1.5 0.9 0.0 0.6 0.3 0.0 3.4 0.3 0.3 0.6 0.2 0.1 2.0 2.1 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 1.3 0.0 0.0 0.2 3.4 0.0 0.0 1.4 0.0 0.0 10.1 0.0 0.1 20.3 1.8 1.1 0.0 0.1 0.0 0.3 0.0 0.0 0.3 2.3 0.0 0.0 0.3 5.4 6.5 0.0 0.1 9.2 0.0 0.3 0.1 0.0 0.4 0.3 0.5 0.9 0.0 0.1 0.0 0.0 1.1 5.6 0.5 0.5 0.2 3.0 0.1 0.6 0.5 0.1 0.1 COL4A5 "ASLN, ATS" ENSG00000188153 "Collagen type IV alpha 5 chain" P29400 X 108439838-108697545 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.9" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 713.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 87.7;HHSteC: 95.0;HUVEC TERT2: 92.8;TIME: 88.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077177 Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "HPA077177: " "unprognostic (2.58e-2)" "unprognostic (2.57e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-2)" "unprognostic (7.27e-2)" "unprognostic (2.70e-1)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.41e-5)" "unprognostic (2.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (1.06e-1)" 7.4 5.6 25.2 2.3 57.4 0.0 8.1 38.2 40.8 38.1 20.0 5.8 3.8 59.2 25.4 9.6 37.5 18.2 10.9 27.0 33.7 16.9 2.4 8.5 1.2 47.7 43.1 23.0 3.8 16.8 19.7 14.5 47.4 37.0 5.6 6.1 7.4 32.9 7.6 26.4 6.3 47.2 36.4 5.5 34.5 6.0 45.3 2.7 10.5 4.4 1.0 47.6 22.7 102.9 4.5 26.7 47.2 14.9 18.0 10.6 0.3 2.8 11.7 14.2 23.2 24.0 1.9 4.2 0.0 2.0 8.6 21.7 13.2 45.2 17.8 6.7 11.7 3.4 87.7 2.9 95.0 0.0 13.5 49.2 53.6 17.4 37.2 45.2 92.8 0.0 0.2 0.1 13.9 2.0 0.1 0.5 14.0 0.0 16.0 0.1 0.0 0.2 35.9 26.7 0.0 0.0 70.2 2.2 6.0 65.6 12.9 0.0 88.8 9.5 2.8 6.4 4.0 1.9 0.0 0.0 8.2 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 57.4 38.2 40.8 27.0 33.7 47.7 43.1 47.4 36.4 45.3 102.9 1.0 6.4 7.3 72.5 0.0 26.9 29.7 29.4 17.1 0.5 14.8 14.7 10.0 2.8 14.2 20.2 0.0 0.7 0.0 0.0 0.0 0.4 0.1 7.4 45.4 4.6 0.0 0.0 1.1 0.9 0.4 12.3 3.1 5.7 1.3 2.0 4.2 0.5 0.4 0.0 1.5 0.2 6.1 0.3 2.1 1.7 20.2 0.6 1.8 20.6 0.0 11.1 0.0 3.5 713.9 0.4 0.0 36.9 0.0 18.1 0.0 0.1 8.2 0.6 6.6 2.4 18.3 0.4 0.9 4.2 15.9 0.7 1.1 21.5 0.1 24.7 COL4A6 ENSG00000197565 "Collagen type IV alpha 6 chain" Q14031 X 108155607-108439497 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 32.6;urinary bladder: 40.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 24.5;Basal respiratory cells: 16.0;Cardiomyocytes: 13.1;Prostatic glandular cells: 12.1;Urothelial cells: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 46.0;HeLa: 40.1;HHSteC: 59.2;hTERT-HME1: 44.1;HUVEC TERT2: 41.7;TIME: 94.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA065393 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Endoplasmic reticulum" "HPA065393: AB_2685483" "unprognostic (8.47e-3)" "unprognostic (4.50e-3)" "unprognostic (9.75e-3)" "unprognostic (9.80e-3)" "unprognostic (1.18e-1)" "unprognostic (5.99e-2)" "unprognostic (1.78e-2)" "unprognostic (3.78e-2)" "unprognostic (1.72e-1)" "unprognostic (9.84e-2)" "unprognostic (1.40e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.32e-2)" "unprognostic (2.06e-1)" "unprognostic (8.54e-3)" "unprognostic (3.51e-1)" 3.0 0.5 0.3 0.4 0.3 0.0 2.0 0.2 0.2 12.6 1.3 1.9 1.4 32.6 17.0 5.5 14.9 13.3 5.4 0.3 0.7 4.2 0.1 1.0 0.1 0.9 1.7 9.3 0.1 5.5 7.2 3.2 1.0 12.5 2.1 1.2 1.4 21.5 1.4 6.5 1.5 24.5 0.4 1.4 13.3 1.2 0.3 0.9 0.7 1.2 0.1 40.7 9.2 0.6 0.1 31.1 9.9 0.0 24.2 1.7 0.0 0.0 1.8 0.3 0.2 17.9 0.0 0.0 0.0 0.0 3.9 5.8 10.3 46.0 0.8 0.4 8.8 0.8 40.1 0.3 59.2 0.0 0.0 2.6 27.8 6.5 44.1 0.1 41.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 14.0 0.0 3.8 0.0 0.0 0.0 1.9 3.4 0.0 0.0 2.4 0.0 0.0 18.2 0.9 0.0 94.2 0.0 0.1 5.5 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.2 0.3 0.7 0.9 1.7 1.0 0.4 0.3 0.6 0.1 0.0 0.0 6.2 0.0 6.4 24.5 16.0 3.4 0.2 2.3 6.1 13.1 0.0 2.6 1.8 0.0 0.1 0.0 0.0 1.9 0.0 2.1 0.7 6.0 0.4 0.0 0.0 0.4 0.0 0.0 6.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 2.0 0.0 0.3 0.3 4.1 0.0 0.0 8.4 0.0 5.5 0.0 0.0 0.6 0.1 0.0 9.1 0.0 12.1 0.0 0.0 2.2 0.4 0.0 0.4 7.2 0.2 0.2 0.1 3.7 0.0 0.1 0.8 0.0 15.2 CPNE7 ENSG00000178773 "Copine 7" Q9UBL6 16 89575758-89597246 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0;epididymis: 19.3;pituitary gland: 14.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.2;Collecting duct cells: 20.2;Excitatory neurons: 9.3;Inhibitory neurons: 9.1;Spermatogonia: 10.2;T-cells: 9.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 4.9" "Lineage enriched" "Detected in single" 5 "T-cells: 4.9" "Cell line enhanced" "Detected in many" "HHSteC: 103.2;TIME: 58.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA043359 Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "HPA043359: AB_10794884" "unprognostic (6.77e-2)" "unprognostic (1.30e-2)" "unprognostic (1.43e-1)" "unprognostic (1.97e-1)" "unprognostic (3.08e-2)" "unprognostic (1.97e-1)" "unprognostic (1.82e-1)" "unprognostic (2.28e-3)" "unprognostic (2.55e-1)" "unprognostic (6.47e-2)" "unprognostic (5.88e-2)" "unprognostic (6.93e-2)" "prognostic unfavorable (9.52e-6)" "unprognostic (1.87e-2)" "unprognostic (1.17e-1)" "unprognostic (3.08e-1)" "prognostic favorable (7.22e-4)" 0.5 0.4 13.5 0.9 13.2 0.9 1.5 0.0 17.6 1.4 0.0 0.7 3.6 0.6 19.3 2.1 2.1 3.3 0.4 15.1 11.4 4.3 1.2 1.7 0.5 2.6 16.2 0.5 0.9 2.4 14.1 0.3 7.4 1.8 0.1 1.6 1.4 6.1 0.0 1.6 3.4 0.2 1.0 0.8 3.2 4.1 28.0 1.6 0.8 0.1 0.4 1.6 1.3 6.0 0.1 24.7 0.2 0.4 40.8 41.8 0.3 10.7 4.5 14.6 11.2 24.8 20.7 0.0 9.5 4.2 0.5 16.8 15.4 0.7 5.0 6.0 12.2 0.2 21.5 0.5 103.2 0.1 4.1 16.3 1.1 7.7 29.0 49.3 0.2 17.4 27.3 0.3 35.1 3.8 8.0 4.8 16.1 15.6 19.1 0.4 0.0 17.6 2.2 0.1 13.7 0.2 3.6 5.2 1.1 0.3 4.6 3.2 58.8 28.4 0.0 17.7 0.0 0.1 0.0 5.0 27.8 17.3 12.0 0.0 0.0 0.1 0.7 0.0 4.9 0.0 1.1 1.8 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.2 0.2 13.5 13.2 0.0 17.6 15.1 11.4 2.6 16.2 7.4 1.0 28.0 6.0 0.5 0.0 0.6 1.3 0.1 2.3 1.1 0.1 0.6 11.2 3.9 5.2 0.8 1.5 0.8 20.2 0.0 0.0 1.4 0.1 0.0 0.9 0.0 1.0 0.5 0.7 0.0 0.4 9.3 0.2 0.2 0.3 3.1 2.2 0.0 0.1 0.4 0.0 0.1 0.0 9.1 0.3 0.0 0.0 0.4 0.6 0.3 0.9 1.8 0.0 0.0 0.3 0.0 3.5 0.6 0.6 0.0 0.7 0.1 1.2 0.7 1.7 0.2 0.9 0.0 0.3 0.5 0.3 10.2 1.2 1.1 0.0 9.5 0.0 1.9 2.1 CREM hCREM-2 ENSG00000095794 "CAMP responsive element modulator" Q03060 10 35126791-35212958 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 216.6" "Cell type enhanced" "Detected in all" "dendritic cells: 819.1;Early spermatids: 2013.6;Langerhans cells: 1094.0;Late spermatids: 814.3;T-cells: 612.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 103.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001818, CAB018352" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 13: T-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "CAB018352: AB_673599, HPA001818: AB_1078566" "unprognostic (1.78e-1)" "unprognostic (6.26e-3)" "unprognostic (7.09e-2)" "unprognostic (2.51e-2)" "unprognostic (6.22e-3)" "unprognostic (9.27e-3)" "unprognostic (1.16e-1)" "unprognostic (2.41e-2)" "unprognostic (1.32e-1)" "unprognostic (7.66e-3)" "unprognostic (8.98e-2)" "unprognostic (3.42e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (4.44e-2)" "unprognostic (4.19e-1)" "unprognostic (1.66e-2)" "unprognostic (1.52e-1)" 54.9 137.4 31.9 51.0 34.3 22.0 27.1 31.3 39.2 26.4 38.6 24.5 8.9 30.3 11.4 17.6 29.2 44.5 50.5 33.6 42.9 58.8 60.5 30.5 17.6 36.7 35.5 60.6 16.0 24.5 59.5 100.3 36.0 32.0 13.6 23.5 13.4 23.3 30.0 9.0 15.9 24.5 34.1 25.3 20.7 216.6 35.8 29.3 22.3 31.3 16.9 60.5 19.1 33.5 24.8 39.0 32.3 33.2 22.2 23.0 32.2 31.8 24.8 19.6 27.0 4.6 10.2 42.0 30.2 18.7 21.2 5.6 28.0 20.8 28.5 103.8 20.6 14.9 25.7 18.6 26.5 3.6 15.2 20.4 25.9 38.3 11.7 17.2 55.3 31.1 44.3 16.9 30.4 20.0 26.1 10.8 9.6 9.2 88.6 16.0 16.9 7.8 34.8 9.7 7.5 20.4 15.1 13.1 88.7 36.5 7.2 11.0 74.0 14.9 19.1 41.4 21.3 7.4 10.9 14.6 35.6 33.1 13.0 5.3 3.5 11.5 11.5 5.5 14.6 7.0 12.6 10.4 4.1 6.8 9.0 10.4 9.7 10.2 4.2 12.4 16.2 8.5 31.9 34.3 31.3 39.2 33.6 42.9 36.7 35.5 36.0 34.1 35.8 33.5 98.7 19.2 47.9 42.7 301.8 143.4 58.0 30.9 18.8 18.3 32.1 32.4 62.3 20.0 33.2 165.5 6.2 98.7 819.1 16.8 97.8 40.6 2013.6 32.6 27.6 118.7 69.0 5.7 50.1 44.4 109.1 140.6 29.0 44.2 347.7 14.5 17.9 37.6 120.6 10.1 34.3 17.9 32.6 61.4 1094.0 814.3 26.1 286.1 247.3 30.0 187.4 39.0 65.9 113.1 34.9 30.6 19.7 32.7 109.4 49.5 15.3 64.2 46.1 19.5 46.0 45.5 232.8 464.7 156.8 15.9 108.4 230.0 612.4 46.4 13.6 52.7 CRTAC1 "ASPIC1, CEP-68, FLJ10320" ENSG00000095713 "Cartilage acidic protein 1" Q9NQ79 10 97865000-98030828 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.6;fallopian tube: 38.2;lung: 50.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 119.5;Club cells: 36.4;Inhibitory neurons: 63.6;Oligodendrocyte precursor cells: 54.8" "Cancer enhanced" "Detected in many" "melanoma: 43.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 3.0;HMC-1: 2.5;HUVEC TERT2: 7.1;SCLC-21H: 4.7;SK-MEL-30: 7.7;TIME: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008175 Enhanced "Secreted to extracellular matrix" NA NA 550000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "HPA008175: AB_1847254" "unprognostic (2.55e-1)" "unprognostic (6.41e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.54e-1)" "unprognostic (6.96e-3)" "unprognostic (9.30e-2)" "unprognostic (9.13e-2)" "unprognostic (1.02e-2)" "unprognostic (3.01e-1)" "unprognostic (7.66e-2)" "unprognostic (1.69e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.70e-4)" "unprognostic (1.05e-2)" "unprognostic (3.29e-3)" "prognostic favorable (1.51e-4)" 4.4 0.8 8.7 1.1 23.7 0.0 2.4 10.9 20.1 6.4 0.9 11.5 0.5 1.3 3.8 8.3 38.2 0.3 10.6 9.1 8.1 4.3 0.4 50.0 0.4 45.1 10.2 0.7 1.3 0.8 5.3 0.0 45.6 2.3 0.4 11.3 3.4 33.6 1.1 4.1 2.3 0.8 12.6 0.1 1.8 3.9 18.5 0.2 4.7 1.5 0.3 30.2 4.9 15.5 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.7 0.0 3.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 4.7 1.1 0.5 0.0 7.7 0.3 0.0 0.0 9.4 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 23.7 10.9 20.1 9.1 8.1 45.1 10.2 45.6 12.6 18.5 15.5 1.9 22.4 119.5 2.9 0.0 1.5 2.7 1.3 5.7 10.1 2.6 2.8 7.1 1.5 36.4 9.2 0.0 0.0 0.1 0.0 0.0 4.6 0.1 0.5 0.1 8.8 1.8 0.0 22.9 0.7 0.0 2.3 0.0 0.6 5.1 0.0 5.7 0.1 0.0 0.0 63.6 0.0 0.0 0.6 0.9 0.6 0.0 0.2 8.8 2.8 0.0 14.1 0.0 54.8 6.2 0.6 0.0 0.4 1.2 1.3 0.0 0.0 0.9 5.3 0.0 3.5 0.3 1.5 1.9 13.1 0.4 0.0 0.4 0.0 0.0 1.7 CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.9;intermediate monocyte: 9.5;myeloid DC: 6.3;non-classical monocyte: 5.6" "Group enriched" "Detected in many" 19 "dendritic cells: 6.3;monocytes: 9.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" 72.6 48.8 29.6 34.8 28.1 5.9 83.3 28.2 33.0 86.0 50.0 107.9 97.8 70.8 49.3 209.7 58.4 56.3 49.0 26.6 26.8 77.9 82.6 83.9 19.0 34.8 30.6 49.3 120.0 76.1 57.7 106.0 32.5 78.9 102.0 23.5 121.8 57.1 26.8 129.4 104.9 54.8 32.3 51.5 105.4 44.3 38.0 24.4 98.6 19.9 48.4 83.5 111.9 33.5 156.6 106.4 70.2 63.3 46.1 71.6 141.7 65.1 78.8 58.5 55.6 88.5 163.9 1.0 113.2 72.5 50.9 201.7 58.8 97.4 71.1 1.0 21.9 32.0 35.8 109.9 52.6 5.0 52.7 70.0 133.5 67.1 73.5 103.8 197.2 1.7 55.1 0.4 55.1 48.0 1.7 13.9 54.7 101.2 56.5 0.7 67.4 1.3 90.2 171.0 4.9 40.1 91.5 133.6 113.1 176.3 138.9 6.1 166.0 59.6 50.3 53.2 34.6 1.2 0.9 2.3 53.2 3.4 111.5 0.0 4.9 0.1 0.0 9.5 0.2 0.2 0.0 0.1 6.3 0.3 0.0 0.0 0.2 0.4 5.6 1.4 0.1 1.1 29.6 28.1 28.2 33.0 26.6 26.8 34.8 30.6 32.5 32.3 38.0 33.5 116.2 147.4 84.0 0.0 8.8 117.1 96.9 82.9 126.9 21.0 101.5 70.5 17.5 125.8 96.6 141.6 39.6 94.0 2.3 305.5 13.7 106.7 14.1 91.1 58.5 98.6 86.2 21.3 0.0 97.2 85.6 34.5 165.1 139.4 32.4 61.1 91.8 127.6 44.4 15.2 0.0 160.7 52.9 64.3 55.5 10.5 28.3 46.4 48.0 0.0 28.5 30.2 2.1 0.0 0.0 141.8 169.3 38.4 5.0 116.9 179.6 57.6 88.2 26.4 26.3 32.3 38.1 37.0 21.1 285.1 200.5 90.8 6.2 39.9 127.0 194.6 DEFB131A "DEFB-31, DEFB131" ENSG00000186146 "Defensin beta 131A" P59861 4 9444534-9450514 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "epididymis: 167.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "thyroid cancer: 1.3" "Group enriched" "Detected in some" 4 "medulla oblongata: 1.2;pons: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "TIME: 2.1" "Secreted in other tissues" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "unprognostic (2.11e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 14.9 0.0 167.4 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 14.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 1.2 0.2 1.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DHDDS "DS, FLJ13102, hCIT, HDS, RP59" ENSG00000117682 "Dehydrodolichyl diphosphate synthase subunit" Q86SQ9 1 26432282-26471306 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease variant, Epilepsy, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 256.5;Early spermatids: 99.1;Rod photoreceptor cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026721, HPA026727" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA026721: AB_1847643, HPA026727: AB_1847644" "unprognostic (1.11e-2)" "unprognostic (5.43e-2)" "unprognostic (5.12e-2)" "unprognostic (9.81e-2)" "unprognostic (6.71e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-3)" "unprognostic (3.81e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-2)" "unprognostic (4.51e-2)" "unprognostic (3.40e-2)" "prognostic favorable (4.08e-7)" "unprognostic (9.42e-2)" "unprognostic (2.85e-1)" "unprognostic (2.22e-1)" "unprognostic (2.95e-1)" 57.3 19.6 12.3 18.9 11.8 12.4 22.7 32.5 14.0 14.6 14.6 37.3 19.1 13.5 38.5 26.3 12.9 15.9 19.8 12.8 13.3 25.5 22.0 13.9 17.6 15.5 16.9 11.4 18.5 39.8 20.9 12.6 18.8 14.1 38.8 37.8 43.3 14.0 13.5 21.2 18.2 18.4 9.0 14.1 23.3 12.3 14.1 14.1 19.1 11.8 20.8 18.1 14.4 12.2 34.2 24.8 20.6 23.8 36.1 28.2 28.4 54.9 33.4 44.0 41.6 37.4 34.6 38.4 33.3 57.2 30.0 24.1 25.4 42.8 42.9 22.7 13.9 38.0 66.9 30.8 39.3 41.4 51.5 40.3 27.6 59.1 32.2 29.4 51.2 26.7 27.3 41.0 39.7 19.4 23.1 20.2 26.3 53.1 36.2 25.3 33.4 31.2 25.4 28.8 24.4 19.4 36.4 38.0 26.6 26.8 29.8 20.9 63.0 30.1 26.3 60.4 32.0 48.1 72.4 39.5 43.0 54.0 26.8 9.4 16.1 9.6 13.8 23.6 9.8 13.2 9.0 9.1 13.6 10.2 7.4 10.9 13.0 10.1 23.1 11.5 8.3 10.5 12.3 11.8 32.5 14.0 12.8 13.3 15.5 16.9 18.8 9.0 14.1 12.2 9.4 9.6 7.8 7.8 13.5 4.6 9.6 12.0 10.8 29.6 9.6 7.4 15.5 15.7 13.8 14.7 256.5 18.3 13.7 76.3 11.7 19.3 99.1 11.6 12.9 11.1 20.9 5.7 26.9 14.5 23.4 11.1 33.6 20.0 19.0 14.4 10.0 13.2 24.5 15.2 28.5 46.3 14.2 11.5 7.1 23.4 10.5 10.5 10.6 10.3 34.4 16.3 14.4 9.0 11.4 17.6 40.3 7.5 18.7 10.6 24.7 29.3 11.5 106.1 0.0 8.4 14.5 13.2 13.5 12.4 5.1 25.4 10.3 15.8 26.0 12.2 DHX29 DDX29 ENSG00000067248 "DExH-box helicase 29" Q7Z478 5 55256055-55307694 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Helicase, Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038317, HPA038318" Approved Approved Cytosol "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA038317: AB_10673169, HPA038318: AB_10672589" "unprognostic (3.43e-2)" "unprognostic (5.09e-1)" "unprognostic (2.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.80e-1)" "unprognostic (2.37e-3)" "unprognostic (1.72e-1)" "unprognostic (6.66e-2)" "unprognostic (1.76e-2)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.57e-3)" "unprognostic (4.01e-1)" "unprognostic (3.85e-1)" "unprognostic (4.78e-3)" "unprognostic (9.40e-2)" 10.6 10.6 5.3 9.7 5.7 6.7 12.0 9.1 7.0 12.5 6.7 12.1 7.2 11.4 6.8 12.7 9.5 8.9 10.7 5.7 5.1 16.9 13.1 9.4 9.5 5.0 5.0 8.9 11.7 18.7 10.4 11.4 5.1 13.4 9.8 8.7 10.3 12.0 24.2 11.6 8.4 12.6 5.5 7.9 10.4 7.4 5.1 10.0 15.4 14.8 9.7 12.0 10.3 7.1 36.7 25.5 20.9 27.2 32.3 28.2 25.6 38.9 30.9 28.2 28.7 21.3 23.0 20.7 34.9 44.5 35.8 26.0 34.0 37.1 40.5 9.1 19.4 18.8 21.6 14.6 18.3 13.3 19.6 23.8 23.0 29.9 17.2 18.5 37.9 16.5 24.4 15.0 33.4 25.9 21.4 11.1 17.5 10.5 27.1 10.9 31.8 35.7 23.0 25.3 19.6 12.5 37.4 21.3 18.6 20.5 28.7 21.7 32.9 25.9 20.2 22.8 27.4 13.2 24.1 29.0 29.9 23.0 29.1 68.6 22.5 24.3 18.0 24.4 20.4 27.3 22.5 20.0 17.5 26.3 25.0 21.6 20.6 24.5 30.1 36.8 21.9 8.9 5.3 5.7 9.1 7.0 5.7 5.1 5.0 5.0 5.1 5.5 5.1 7.1 44.5 70.5 42.6 34.0 35.2 37.6 37.5 71.8 39.3 81.6 44.9 49.8 73.6 41.5 69.4 64.4 41.7 68.3 39.5 34.4 54.8 61.4 54.8 37.4 61.5 40.7 38.4 68.4 47.3 61.7 54.6 52.7 35.7 36.5 31.6 39.0 22.9 45.0 41.2 42.1 46.9 36.4 63.1 26.0 26.6 16.6 46.6 41.5 28.4 28.1 50.7 35.7 35.0 42.7 54.9 61.9 27.3 53.0 57.0 53.2 35.2 105.2 35.9 83.6 52.6 52.8 54.2 117.5 108.1 50.1 47.5 81.3 36.1 106.4 39.9 43.3 DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Adipocytes: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 57 "HUVEC TERT2: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" 40.8 5.3 14.4 6.1 15.0 0.8 36.9 11.7 13.9 19.6 7.8 9.1 2.6 20.5 6.9 6.5 18.0 8.8 27.3 11.4 13.1 7.0 1.4 14.1 5.7 14.4 14.2 6.9 3.5 4.6 3.3 40.5 14.1 11.3 3.8 1.4 6.8 7.2 16.6 7.4 7.7 20.7 12.4 3.1 6.3 1.5 14.8 2.7 18.5 16.6 3.4 14.3 13.9 15.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 81.7 0.1 0.0 0.5 0.0 0.1 0.0 0.3 0.1 1.4 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.4 15.0 11.7 13.9 11.4 13.1 14.4 14.2 14.1 12.4 14.8 15.4 96.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DIXDC1 "Dixin, KIAA1735" ENSG00000150764 "DIX domain containing 1" Q155Q3 11 111927144-112022653 "Predicted intracellular proteins" "Wnt signaling pathway" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 104.3;Horizontal cells: 121.1;Oligodendrocytes: 140.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "eosinophil: 5.2" "Lineage enriched" "Detected in single" 11 "granulocytes: 5.2" "Cell line enhanced" "Detected in many" "hTERT-HME1: 42.7;TIME: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039424, HPA039658, HPA061366" Approved Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA039424: AB_2676500, HPA039658: AB_2676611, HPA061366: " "unprognostic (1.93e-1)" "unprognostic (2.90e-2)" "unprognostic (8.93e-3)" "unprognostic (2.84e-1)" "unprognostic (2.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.37e-1)" "unprognostic (1.41e-1)" "unprognostic (7.23e-2)" "unprognostic (1.59e-1)" "unprognostic (7.85e-2)" "unprognostic (5.11e-2)" "prognostic favorable (6.89e-5)" "unprognostic (4.10e-2)" "unprognostic (2.11e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (4.19e-5)" 17.8 17.7 16.4 8.6 23.2 0.7 15.0 36.8 22.6 18.7 22.8 29.5 5.6 24.8 18.6 12.7 20.4 12.6 23.3 17.0 16.9 11.4 7.0 9.4 2.6 20.1 21.8 15.8 3.8 17.1 7.1 10.8 19.1 23.4 10.0 22.0 7.8 35.8 13.7 5.4 9.1 25.6 18.0 2.9 14.9 19.1 19.7 2.6 10.7 12.3 2.5 25.3 12.0 34.4 0.8 3.7 9.9 18.5 29.9 17.5 2.1 7.7 5.3 2.9 5.2 0.6 2.0 1.6 2.0 21.5 3.4 0.9 4.4 2.4 2.9 6.4 3.7 0.8 5.8 10.3 4.6 5.3 0.7 14.2 19.3 6.3 42.7 21.5 30.6 4.0 5.2 0.6 11.9 0.9 3.3 4.6 5.9 0.8 6.6 1.6 2.9 6.1 12.1 0.3 8.0 16.7 5.7 4.6 2.5 4.3 6.8 2.0 50.4 13.1 5.6 2.4 12.9 1.2 5.5 0.8 7.2 13.5 4.7 0.0 0.1 5.2 0.3 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.1 16.4 23.2 36.8 22.6 17.0 16.9 20.1 21.8 19.1 18.0 19.7 34.4 12.8 16.0 10.3 40.1 0.4 6.4 16.3 4.1 11.4 22.3 23.7 28.8 35.6 7.2 10.1 18.4 104.3 1.4 0.9 2.6 15.6 6.4 23.1 32.1 48.6 28.1 2.4 2.1 47.7 7.7 5.1 32.8 11.7 11.3 1.3 6.3 62.8 19.3 1.7 121.1 83.8 13.9 6.1 3.4 5.3 17.5 39.7 1.5 12.4 20.6 1.0 30.2 0.0 34.7 140.4 7.0 6.2 36.9 2.0 10.8 2.7 15.4 35.5 69.2 13.1 25.3 31.8 62.3 16.4 3.3 4.1 1.4 2.0 3.5 4.5 3.1 DNAJB4 HLJ1 ENSG00000162616 "DnaJ heat shock protein family (Hsp40) member B4" Q9UDY4 1 77979175-78017964 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 119.0;HUVEC TERT2: 182.3;LHCN-M2: 312.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004995, HPA028383, HPA028385" Approved Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 9500 "Cluster 44: Non-specific - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "CAB004995: AB_425882, HPA028383: AB_10599601, HPA028385: AB_10599944" "unprognostic (1.21e-1)" "unprognostic (4.36e-2)" "unprognostic (2.19e-1)" "unprognostic (5.50e-3)" "unprognostic (3.40e-2)" "unprognostic (4.76e-3)" "unprognostic (4.32e-3)" "unprognostic (3.93e-3)" "unprognostic (1.53e-1)" "unprognostic (2.16e-1)" "unprognostic (2.00e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.60e-2)" "unprognostic (1.51e-1)" "unprognostic (7.12e-3)" "unprognostic (1.01e-2)" 31.6 49.7 21.9 11.1 24.2 6.7 15.4 24.4 74.6 24.0 19.9 14.3 6.4 21.3 10.8 26.4 13.9 32.3 50.4 23.1 27.1 20.6 20.0 17.0 9.7 23.0 24.8 16.0 22.8 14.1 11.6 26.0 23.0 23.3 11.2 15.0 7.6 14.1 44.1 9.6 9.6 29.9 23.3 42.2 12.3 7.9 25.9 10.5 44.5 71.4 6.2 23.6 12.8 35.3 6.2 11.8 14.5 8.6 61.8 115.0 6.7 119.0 28.8 50.8 56.8 3.9 8.0 8.9 19.4 55.5 20.7 9.2 18.7 10.1 86.1 10.1 5.3 4.5 32.9 28.7 84.1 2.5 2.4 47.9 27.9 66.5 18.9 28.4 182.3 2.9 19.6 6.1 312.1 0.7 3.0 6.6 9.4 1.8 5.6 5.0 25.2 5.9 12.0 3.1 10.8 3.4 13.3 10.0 11.7 15.0 3.9 3.7 88.7 72.5 17.8 51.2 15.9 5.5 1.8 7.9 9.9 5.3 12.9 3.3 0.7 1.2 1.1 0.8 1.8 1.6 1.3 1.3 0.7 1.3 3.0 2.1 0.2 1.6 0.9 2.3 1.9 0.9 21.9 24.2 24.4 74.6 23.1 27.1 23.0 24.8 23.0 23.3 25.9 35.3 81.5 60.9 6.3 35.9 23.9 41.7 112.5 16.3 48.3 29.3 90.9 57.1 98.7 18.6 20.0 18.4 68.8 51.2 15.3 40.9 37.2 11.2 144.7 55.1 37.3 84.4 21.4 42.1 41.6 14.7 23.2 87.3 45.9 51.9 56.6 16.7 42.8 22.3 19.4 30.3 39.0 37.9 12.2 18.3 70.1 62.6 24.5 33.7 65.8 21.5 5.1 40.5 8.2 28.6 53.8 11.4 27.3 35.0 70.6 33.9 16.8 31.0 34.7 56.5 26.3 82.8 120.3 23.1 12.0 55.5 39.2 181.0 52.7 32.1 30.9 43.2 DNASE1L1 "DNAS1L1, DNASEX, DNL1L, XIB" ENSG00000013563 "Deoxyribonuclease 1 like 1" P49184 X 154401236-154412112 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 147.0" "Cell type enhanced" "Detected in many" "Kupffer cells: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072635 Approved "Intracellular and membrane" NA NA 96000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "HPA072635: AB_2686542" "unprognostic (5.27e-2)" "unprognostic (1.95e-1)" "unprognostic (4.57e-3)" "unprognostic (2.97e-1)" "unprognostic (1.27e-2)" "unprognostic (1.59e-3)" "unprognostic (3.82e-2)" "unprognostic (3.08e-2)" "unprognostic (2.88e-1)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (4.98e-1)" "prognostic favorable (2.19e-4)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "unprognostic (6.75e-2)" 18.7 26.6 12.6 13.0 12.1 24.1 17.8 11.7 14.1 15.8 26.6 15.2 15.2 15.8 22.5 21.6 14.0 13.0 43.2 13.5 14.3 20.9 18.8 22.0 16.4 12.2 13.4 13.7 12.8 22.7 20.1 16.1 12.6 15.1 12.3 3.9 22.0 11.3 147.0 11.3 19.3 11.3 13.0 28.5 18.1 7.7 13.6 8.9 24.1 94.8 13.2 13.5 16.9 11.9 19.7 19.6 6.3 12.2 56.6 74.5 7.7 54.5 85.3 17.6 34.6 5.7 28.0 32.9 68.2 103.0 67.4 9.6 7.6 31.0 12.8 9.9 13.0 4.8 20.6 7.1 38.8 8.6 33.4 55.6 35.7 39.6 40.0 47.9 76.4 5.3 6.5 34.0 61.1 33.0 3.6 4.2 5.0 35.5 22.1 7.3 28.5 52.9 31.0 9.7 20.2 12.0 17.1 29.9 22.5 13.9 11.9 7.8 112.9 17.7 20.3 25.6 10.9 64.2 15.4 34.4 26.6 14.4 22.4 13.0 12.0 17.1 3.5 21.6 4.0 6.2 3.3 3.1 14.5 4.1 2.4 2.2 7.0 4.6 20.9 8.3 4.9 6.4 12.6 12.1 11.7 14.1 13.5 14.3 12.2 13.4 12.6 13.0 13.6 11.9 20.1 6.4 6.5 3.3 8.0 1.3 7.1 11.1 9.6 1.8 5.1 3.8 2.0 5.7 5.4 5.5 0.0 5.3 6.7 15.5 9.8 6.1 0.1 5.8 5.7 17.7 6.1 6.5 3.2 10.2 23.3 5.2 11.7 7.5 13.3 4.9 23.2 8.6 29.1 0.0 2.2 10.4 6.1 36.6 11.7 1.2 3.4 25.4 16.0 4.7 22.9 12.8 7.2 0.0 0.5 13.5 18.1 2.6 6.8 5.9 27.0 9.6 7.0 1.4 0.0 16.7 3.3 0.4 0.4 10.4 1.7 8.9 6.0 3.2 10.9 10.9 DOCK4 "FLJ34238, KIAA0716" ENSG00000128512 "Dedicator of cytokinesis 4" Q8N1I0 7 111726110-112206407 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.6" "Group enriched" "Detected in many" 4 "Astrocytes: 791.0;Excitatory neurons: 422.8;Microglial cells: 1568.3;Oligodendrocyte precursor cells: 434.3;Oligodendrocytes: 815.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 43.3;HUVEC TERT2: 75.5;TIME: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071516 Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Plasma membrane" "Golgi apparatus, Cytosol" "HPA071516: AB_2686407" "unprognostic (1.37e-1)" "unprognostic (4.18e-1)" "unprognostic (1.53e-1)" "unprognostic (2.48e-2)" "unprognostic (7.10e-2)" "unprognostic (2.03e-2)" "unprognostic (9.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" "unprognostic (5.78e-2)" "unprognostic (7.06e-2)" "unprognostic (3.66e-1)" "unprognostic (5.71e-2)" "unprognostic (1.89e-2)" "unprognostic (9.48e-2)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" 7.8 4.4 17.1 6.6 41.6 1.4 4.8 11.4 21.9 5.0 0.0 3.2 1.5 4.6 2.8 2.5 5.2 5.0 4.9 40.6 17.8 4.5 10.0 17.3 2.7 16.5 18.1 8.4 3.2 3.3 3.2 6.9 15.6 4.0 2.8 10.5 3.3 2.5 6.2 2.5 2.4 7.3 14.9 1.8 2.2 2.1 19.2 1.7 3.5 7.3 2.2 3.7 3.5 26.0 0.1 3.5 8.8 7.8 7.2 10.4 5.3 1.0 9.6 1.7 2.8 0.0 0.2 0.8 7.6 2.3 2.0 0.5 1.5 8.8 6.5 2.9 12.9 0.4 5.8 14.3 5.1 1.1 0.4 4.9 1.0 43.3 20.8 3.0 75.5 3.4 0.1 22.6 3.8 1.0 2.0 0.7 5.1 1.5 15.8 0.8 7.0 3.6 6.0 0.5 1.9 7.5 6.2 4.3 5.8 8.2 0.8 0.4 69.0 6.6 3.4 13.7 3.0 1.2 0.5 0.9 0.7 1.8 16.5 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.1 0.1 0.0 0.1 17.1 41.6 11.4 21.9 40.6 17.8 16.5 18.1 15.6 14.9 19.2 26.0 56.4 48.1 6.8 791.0 1.1 5.2 3.3 7.5 8.6 27.4 3.7 6.3 13.1 2.8 16.7 3.7 22.9 0.3 0.1 2.3 0.0 2.1 3.8 1.3 5.5 47.1 10.9 5.3 422.8 0.4 0.2 21.4 0.5 2.2 2.5 5.0 43.9 17.0 14.6 94.2 177.1 0.7 14.2 16.7 21.0 1.5 5.6 27.4 8.8 1568.3 6.1 5.4 0.0 434.3 815.3 1.2 8.0 8.2 0.2 8.2 0.0 1.8 12.2 11.4 13.1 4.2 5.8 0.6 1.9 2.3 2.7 0.0 0.6 26.2 1.5 1.8 DOCK6 "KIAA1395, ZIR1" ENSG00000130158 "Dedicator of cytokinesis 6" Q96HP0 19 11199295-11262524 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 70.3;Cardiomyocytes: 185.4;Endothelial cells: 64.8;Hepatic stellate cells: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 68.2;TIME: 68.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049423, HPA049424" Approved Supported Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA049423: AB_2680760, HPA049424: AB_2680761" "unprognostic (2.69e-2)" "unprognostic (2.27e-1)" "unprognostic (9.51e-2)" "unprognostic (3.35e-2)" "unprognostic (4.72e-3)" "prognostic favorable (9.09e-4)" "unprognostic (2.54e-2)" "unprognostic (4.91e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-2)" "unprognostic (2.57e-1)" "unprognostic (7.89e-2)" "unprognostic (1.25e-3)" "unprognostic (2.76e-1)" "unprognostic (1.51e-1)" "unprognostic (5.41e-2)" "unprognostic (2.95e-1)" 31.2 9.9 7.4 5.4 6.3 0.4 27.5 4.5 9.7 15.4 3.6 16.8 14.2 14.7 4.6 16.8 11.6 12.0 29.6 4.6 5.1 26.3 13.2 46.3 4.9 7.8 7.1 12.0 14.4 5.4 11.9 15.0 6.9 14.8 6.2 1.8 11.4 7.5 15.1 25.2 15.4 7.1 5.7 14.5 15.8 5.8 11.4 2.1 29.0 9.3 2.6 14.2 16.6 5.6 14.6 8.9 9.9 8.1 7.3 10.5 15.9 4.2 6.9 4.1 6.3 16.9 11.2 0.9 25.4 7.1 3.9 8.3 4.3 22.3 2.5 12.4 7.0 2.8 2.2 12.8 11.8 4.3 13.7 8.1 13.0 7.5 17.0 7.9 68.2 0.3 15.7 0.0 9.1 32.7 0.1 14.7 12.5 13.2 16.6 0.9 6.7 14.0 6.8 20.0 0.6 17.6 4.2 4.2 7.6 6.5 4.9 7.6 68.8 7.5 7.8 17.1 7.6 1.2 0.2 14.1 6.3 3.2 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 6.3 4.5 9.7 4.6 5.1 7.8 7.1 6.9 5.7 11.4 5.6 70.3 3.2 12.6 6.8 0.9 6.5 6.2 8.5 4.6 1.4 4.3 3.8 185.4 5.7 11.3 25.8 0.0 0.3 0.9 15.6 1.9 5.4 3.5 3.9 8.9 64.8 12.1 0.0 2.9 6.8 1.3 19.6 35.2 7.2 5.1 4.7 55.3 5.6 4.6 0.0 5.9 15.9 8.2 2.5 4.4 1.3 22.4 1.6 3.6 35.6 0.0 4.6 0.0 7.1 3.5 11.9 10.9 9.4 1.9 8.4 11.9 1.9 9.2 2.6 19.7 8.4 30.8 1.5 4.3 7.4 11.5 0.5 1.2 7.8 9.7 9.0 DOCK9 "KIAA1058, ZIZ1" ENSG00000088387 "Dedicator of cytokinesis 9" Q9BZ29 13 98793429-99086625 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 216.7" "Cell type enhanced" "Detected in many" "Adipocytes: 158.7;Excitatory neurons: 150.6;Inhibitory neurons: 202.2;Microglial cells: 148.0;Oligodendrocyte precursor cells: 238.8;Oligodendrocytes: 402.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 2.0;MAIT T-cell: 4.8;memory CD4 T-cell: 5.2;memory CD8 T-cell: 2.1;naive CD4 T-cell: 6.0;naive CD8 T-cell: 4.0;NK-cell: 7.3;T-reg: 2.4" "Group enriched" "Detected in many" 11 "NK-cells: 7.3;T-cells: 6.0" "Cell line enhanced" "Detected in many" "BEWO: 200.8;hTERT-HME1: 435.4;HUVEC TERT2: 180.9;TIME: 179.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034061, CAB034065, HPA043940" Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB034061: AB_2277513, CAB034065: AB_2094798, HPA043940: AB_2678741" "unprognostic (5.31e-2)" "unprognostic (3.20e-2)" "unprognostic (8.76e-2)" "unprognostic (4.24e-2)" "unprognostic (1.88e-1)" "unprognostic (1.48e-1)" "unprognostic (3.62e-2)" "unprognostic (2.96e-1)" "unprognostic (2.47e-1)" "unprognostic (1.16e-1)" "unprognostic (6.38e-3)" "unprognostic (2.79e-1)" "unprognostic (7.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.17e-1)" "unprognostic (1.36e-2)" "unprognostic (3.31e-2)" 83.2 22.4 82.6 21.4 137.2 6.0 71.1 96.6 91.0 42.9 30.8 44.4 15.7 31.3 35.5 93.1 30.3 36.6 58.9 72.8 93.8 21.9 15.8 93.0 33.8 116.6 112.1 27.4 19.9 41.8 21.1 98.2 123.4 23.0 20.8 39.5 51.2 21.7 25.9 76.9 35.2 36.9 86.6 16.8 24.7 16.2 110.4 47.8 62.6 64.3 40.4 29.0 49.6 216.7 61.6 19.4 10.6 14.2 10.6 8.3 200.8 17.2 14.2 12.1 10.7 127.4 47.7 51.3 39.8 16.6 21.8 59.5 27.4 54.3 21.8 52.2 15.2 0.0 37.6 2.1 14.0 0.1 2.9 9.0 37.2 12.4 435.4 27.9 180.9 33.0 10.6 11.6 52.1 20.2 35.5 0.3 4.9 84.6 14.2 2.1 39.3 2.7 38.3 50.8 22.4 24.3 26.4 63.4 15.7 85.9 16.9 0.4 179.7 9.7 11.4 6.5 28.5 17.6 14.8 8.6 15.6 0.0 16.0 0.0 0.0 0.0 2.0 0.0 4.8 0.6 5.2 2.1 0.0 0.2 6.0 4.0 0.1 7.3 0.0 0.0 2.4 1.5 82.6 137.2 96.6 91.0 72.8 93.8 116.6 112.1 123.4 86.6 110.4 216.7 158.7 16.0 39.5 37.5 3.4 15.3 7.1 14.7 10.2 37.9 15.4 6.5 9.4 11.5 12.5 9.2 50.1 35.6 7.0 11.9 1.9 5.4 1.7 10.5 5.3 90.2 6.7 3.6 150.6 6.6 8.3 17.2 2.6 21.4 2.5 18.0 47.8 8.4 5.0 25.2 202.2 6.0 10.2 1.9 7.4 3.3 7.8 1.7 1.8 148.0 0.4 12.9 4.1 238.8 402.2 14.7 5.6 14.7 2.8 10.1 10.6 3.8 7.1 23.9 0.0 122.6 12.4 7.2 5.4 25.6 32.0 17.2 11.0 2.4 5.9 10.5 DRP2 ENSG00000102385 "Dystrophin related protein 2" Q13474 X 101219769-101264502 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.8;lymphoid tissue: 4.7" "Group enriched" "Detected in some" 6 "Excitatory neurons: 35.6;Inhibitory neurons: 24.5;Oligodendrocyte precursor cells: 11.1" "Cancer enhanced" "Detected in single" "glioma: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RH-30: 10.7;TIME: 18.5;U-87 MG: 4.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 56.0" HPA002949 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Plasma membrane" "HPA002949: AB_1078706" "unprognostic (8.47e-4)" "unprognostic (3.56e-3)" "unprognostic (1.01e-2)" "unprognostic (5.58e-4)" "unprognostic (1.74e-2)" "unprognostic (2.47e-2)" "unprognostic (7.93e-3)" "unprognostic (2.94e-3)" "unprognostic (1.27e-2)" "unprognostic (5.46e-3)" "unprognostic (1.42e-1)" "unprognostic (4.61e-2)" "unprognostic (4.44e-16)" "unprognostic (3.71e-4)" "unprognostic (4.22e-1)" "unprognostic (9.03e-2)" "unprognostic (1.25e-1)" 0.7 0.3 4.0 0.2 5.9 0.2 0.4 0.0 8.8 0.6 0.0 3.2 0.2 0.7 0.7 0.2 0.2 0.2 0.2 6.2 0.7 0.0 0.0 0.0 0.0 0.1 2.6 1.4 0.0 0.0 2.3 0.0 0.6 1.3 0.4 1.0 0.6 0.9 0.2 0.3 0.8 0.6 0.0 0.0 0.3 0.5 0.7 4.7 0.0 1.1 0.0 0.6 1.1 4.8 0.0 0.6 2.2 0.1 0.1 0.2 0.1 0.4 0.1 0.3 0.9 0.0 0.4 0.3 0.2 0.1 0.6 0.0 0.3 0.0 0.7 0.1 0.2 0.2 0.6 0.0 0.2 0.1 0.4 1.4 0.0 0.7 0.0 0.0 1.4 0.5 0.0 0.9 1.5 0.0 1.3 0.5 0.1 0.1 0.1 0.3 10.7 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.4 0.0 0.1 18.5 0.2 0.7 0.2 0.4 0.0 0.1 0.0 4.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.9 0.0 8.8 6.2 0.7 0.1 2.6 0.6 0.0 0.7 4.8 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 1.8 0.0 35.6 0.0 0.1 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 24.5 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.3 0.0 11.1 1.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DUSP18 DUSP20 ENSG00000167065 "Dual specificity phosphatase 18" Q8NEJ0 22 30652051-30667887 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 123.4;Late spermatids: 344.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034070, HPA051349" Uncertain Supported Nucleoplasm Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "CAB034070: AB_2094867, HPA051349: AB_2681450" "unprognostic (1.11e-1)" "unprognostic (2.34e-2)" "unprognostic (3.49e-3)" "unprognostic (4.88e-3)" "unprognostic (1.88e-1)" "unprognostic (9.12e-2)" "unprognostic (3.77e-4)" "unprognostic (1.83e-1)" "unprognostic (1.61e-1)" "unprognostic (3.53e-2)" "unprognostic (9.62e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-3)" "unprognostic (6.55e-2)" "unprognostic (1.97e-1)" "unprognostic (4.56e-2)" "unprognostic (1.02e-1)" 3.3 1.9 3.4 4.5 3.6 3.3 2.8 2.9 5.3 2.4 9.1 5.4 5.0 2.9 4.9 4.1 10.9 4.2 2.0 3.7 4.0 2.2 1.0 5.5 4.7 5.4 7.6 2.4 2.9 3.3 4.2 2.1 4.9 2.1 6.8 5.2 2.5 2.4 1.3 4.8 4.6 3.8 4.8 4.3 4.8 13.9 4.5 4.0 3.3 1.6 3.9 3.3 2.6 6.0 5.4 5.4 2.5 5.8 6.2 11.9 2.3 4.9 5.3 4.7 5.1 3.1 5.3 3.6 3.3 6.0 6.2 3.8 1.3 3.8 5.3 9.8 6.1 1.5 2.2 2.2 2.6 7.4 5.3 3.1 5.4 7.8 3.0 5.3 15.0 4.1 1.7 2.8 5.2 4.8 4.2 1.8 0.8 6.4 3.3 2.8 1.7 1.2 5.6 3.7 6.2 3.7 4.8 1.7 3.5 3.2 4.5 2.2 11.1 9.9 5.4 2.7 2.8 2.1 2.6 1.7 11.4 1.3 5.0 31.4 15.3 29.9 8.6 19.3 6.6 9.7 9.6 7.7 17.2 8.7 6.6 7.5 31.8 7.4 21.4 9.7 13.2 8.4 3.4 3.6 2.9 5.3 3.7 4.0 5.4 7.6 4.9 4.8 4.5 6.0 7.2 19.2 5.4 11.4 7.1 21.4 13.3 6.5 2.2 2.9 4.9 3.4 2.0 10.0 9.6 5.5 45.9 1.2 12.0 10.0 3.9 10.1 123.4 34.5 5.0 10.1 35.5 2.1 8.0 9.4 3.9 6.8 8.6 5.0 7.0 4.4 13.9 1.1 8.1 1.7 4.4 15.4 6.1 15.6 28.5 344.2 8.4 13.2 8.8 13.1 13.9 10.1 9.2 1.5 14.3 9.3 15.4 6.8 3.9 8.8 24.2 4.1 64.6 16.8 6.6 8.6 6.6 63.0 17.2 5.7 21.3 1.0 9.7 3.5 19.0 8.7 DYNC1I2 "DIC74, DNCI2" ENSG00000077380 "Dynein cytoplasmic 1 intermediate chain 2" Q13409 2 171687409-171750158 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transport" "Motor protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033836, HPA040619, HPA053987" Supported Supported "Nucleoli,Endoplasmic reticulum,Microtubules,Cytosol" NA NA 82000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum, Cytosol" "Nucleoli, Microtubules" "CAB033836: AB_2093633, HPA040619: AB_2677045, HPA053987: AB_2682334" "unprognostic (3.01e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-2)" "unprognostic (8.15e-2)" "unprognostic (8.90e-2)" "unprognostic (1.37e-3)" "unprognostic (2.51e-3)" "unprognostic (6.30e-3)" "unprognostic (1.23e-1)" "unprognostic (1.89e-2)" "unprognostic (1.40e-2)" "unprognostic (4.19e-1)" "prognostic favorable (8.04e-4)" "unprognostic (1.76e-1)" "unprognostic (1.47e-1)" "unprognostic (1.35e-3)" "unprognostic (6.42e-2)" 65.1 58.5 89.2 44.4 121.1 23.1 65.3 122.6 185.9 62.3 70.4 62.3 54.3 74.5 51.0 68.3 47.1 58.6 65.9 89.2 101.4 80.0 41.3 51.7 38.7 130.5 116.2 71.7 38.7 68.2 29.4 76.2 124.1 59.9 64.7 63.5 46.7 60.3 51.0 48.8 51.0 80.4 104.0 41.4 49.3 55.9 112.9 60.0 56.3 57.7 47.4 72.3 53.3 155.5 87.5 55.0 167.0 61.9 151.2 144.0 94.2 149.2 115.7 122.9 133.7 96.5 84.4 79.2 127.7 178.8 168.0 86.2 132.5 143.5 159.8 30.1 59.7 69.3 65.7 109.6 75.5 80.0 71.7 113.0 133.4 152.3 97.3 171.7 219.1 76.5 112.1 21.3 246.1 54.4 68.9 65.7 77.0 127.0 55.5 68.7 149.8 58.3 163.3 138.0 105.8 116.6 82.7 65.6 90.6 126.0 64.1 77.3 238.3 185.9 91.9 75.2 90.9 26.3 54.0 64.5 126.8 64.2 139.2 209.6 93.9 49.2 50.7 98.0 54.3 77.2 58.1 59.4 68.7 71.1 51.7 49.5 5.8 64.4 100.1 111.8 66.2 39.6 89.2 121.1 122.6 185.9 89.2 101.4 130.5 116.2 124.1 104.0 112.9 155.5 146.2 198.7 60.6 30.3 49.2 50.6 59.2 138.5 19.9 73.1 101.7 87.1 75.4 158.7 124.8 169.2 64.6 101.9 46.3 169.5 131.0 207.6 129.5 118.2 147.3 117.1 84.3 95.2 102.4 161.5 107.5 91.2 42.8 172.6 102.3 69.3 174.9 150.7 101.1 80.8 104.9 140.0 116.0 148.1 39.8 48.0 128.6 75.9 35.6 45.9 156.2 91.3 70.0 35.7 182.4 189.2 126.9 138.0 22.7 44.7 139.2 270.3 108.0 128.9 111.7 61.4 111.0 248.4 95.2 43.2 60.0 115.6 46.7 60.6 123.9 58.5 DYNC1LI2 DNCLI2 ENSG00000135720 "Dynein cytoplasmic 1 light intermediate chain 2" O43237 16 66720893-66751609 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 311.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049538, HPA057201" Approved Approved Centrosome,Cytosol NA NA 21000 "Cluster 18: Basophils - Vesicular transport" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 1: Pancreatic cells - Digestion" Centrosome Cytosol "HPA049538: , HPA057201: AB_2683366" "unprognostic (6.03e-2)" "unprognostic (2.40e-2)" "unprognostic (8.28e-2)" "unprognostic (1.57e-2)" "unprognostic (5.35e-2)" "unprognostic (2.80e-1)" "unprognostic (7.58e-2)" "unprognostic (3.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (1.67e-2)" "unprognostic (1.88e-1)" "unprognostic (6.51e-3)" "unprognostic (4.77e-2)" "unprognostic (1.92e-1)" "unprognostic (7.70e-3)" "unprognostic (1.34e-1)" 60.9 44.9 225.7 39.2 240.6 42.4 44.1 207.1 311.6 46.2 131.4 70.5 43.3 50.7 40.6 50.6 37.7 48.7 59.4 184.1 202.3 43.0 29.1 45.9 27.0 228.5 228.0 45.5 44.7 65.7 35.6 46.8 226.2 52.7 61.1 37.3 48.6 49.9 42.3 51.3 44.6 64.9 244.5 36.3 50.2 34.1 221.3 24.6 61.6 49.9 28.8 45.7 40.8 265.1 52.5 54.0 79.1 71.0 100.1 98.3 71.6 84.5 67.1 67.5 87.0 73.4 50.6 21.9 64.6 83.3 49.1 74.1 61.2 60.4 98.2 14.9 43.9 27.0 68.1 70.6 55.5 29.0 38.5 64.8 80.6 77.8 53.4 94.3 96.2 22.4 44.4 28.0 88.8 37.5 18.1 37.5 47.5 58.4 93.0 39.4 166.3 26.5 67.2 73.3 78.8 54.9 152.1 32.6 100.6 56.5 39.7 28.8 123.2 86.9 43.3 43.0 58.2 35.3 27.4 43.0 74.6 27.7 55.8 13.6 16.6 16.6 12.3 9.9 14.2 4.8 10.4 10.2 12.2 9.4 8.7 8.4 15.7 9.3 14.5 7.6 11.4 8.7 225.7 240.6 207.1 311.6 184.1 202.3 228.5 228.0 226.2 244.5 221.3 265.1 117.9 102.5 120.4 44.1 29.5 66.2 63.1 66.1 52.3 82.5 54.8 51.2 48.3 54.3 93.8 27.6 33.3 61.3 47.2 114.0 7.9 85.7 112.6 77.6 68.5 97.6 106.1 28.4 50.9 58.1 62.0 66.7 52.5 87.4 36.7 87.5 62.4 33.3 30.6 107.7 45.4 78.6 65.1 39.9 53.7 66.8 63.3 36.8 69.4 34.7 37.8 116.0 35.0 51.3 106.9 101.7 56.7 80.5 37.3 83.6 60.0 49.4 105.0 61.4 118.3 93.4 87.0 103.0 51.1 53.6 69.9 84.8 32.2 61.2 66.7 95.8 DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453722-71686768 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 95.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Endothelial cells: 43.7;Excitatory neurons: 34.7;Hepatic stellate cells: 32.2;Kupffer cells: 27.1;Oligodendrocytes: 62.7;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.0" "Group enriched" "Detected in many" 5 "hTERT-RPE1: 31.9;HUVEC TERT2: 85.5;LHCN-M2: 75.3;RH-30: 78.5;TIME: 58.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" 10.1 1.7 1.0 11.5 1.1 31.6 4.3 4.1 7.7 1.9 0.7 7.0 2.0 2.3 0.5 7.4 3.2 4.6 16.8 0.2 3.8 3.6 6.5 8.3 3.7 14.8 5.1 1.3 1.5 2.3 1.5 21.1 13.7 3.3 2.5 0.5 1.3 4.8 95.3 1.2 3.1 10.2 2.0 21.4 2.5 1.1 10.2 2.3 4.6 32.3 0.9 6.9 1.8 1.8 1.1 0.0 3.3 3.0 0.0 0.0 6.1 0.1 0.8 2.2 1.5 0.4 1.0 0.0 12.1 0.1 3.4 2.5 0.0 1.2 1.1 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.0 1.5 0.0 2.3 10.6 31.9 85.5 0.2 8.4 0.0 75.3 0.0 0.0 5.8 8.1 0.0 0.9 0.0 78.5 0.0 2.6 0.2 0.0 0.0 4.1 0.7 0.1 7.9 0.3 0.8 58.1 0.3 3.8 0.2 1.1 0.0 0.0 0.0 0.0 13.3 0.0 0.0 4.1 0.1 0.5 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 27.0 0.4 0.1 0.0 0.0 1.4 1.0 1.1 4.1 7.7 0.2 3.8 14.8 5.1 13.7 2.0 10.2 1.8 30.5 3.2 8.1 1.0 1.0 2.4 0.0 0.1 0.0 1.1 0.3 0.6 24.0 0.0 1.3 0.0 0.0 8.1 0.7 0.1 0.0 0.4 4.8 0.7 1.3 43.7 0.0 2.7 34.7 0.2 3.8 2.2 0.0 9.3 2.5 0.3 32.2 13.4 11.4 0.0 13.0 0.2 0.0 27.1 3.0 6.0 0.6 10.2 0.0 16.9 5.8 0.1 0.0 2.5 62.7 0.1 0.0 0.7 0.1 0.2 0.0 2.1 0.7 0.2 6.6 5.2 5.5 0.6 1.1 0.1 1.6 66.2 1.1 0.9 0.0 0.1 ECE1 ECE ENSG00000117298 "Endothelin converting enzyme 1" P42892 1 21217247-21345572 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 29.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 673.8;TIME: 588.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001490, HPA013616" Enhanced NA NA 1300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA001490: AB_1078718, HPA013616: AB_1847963" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (1.49e-2)" "unprognostic (1.46e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (6.20e-2)" "unprognostic (1.92e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (7.70e-2)" "unprognostic (3.55e-2)" "unprognostic (9.10e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-2)" 87.3 123.2 26.5 47.7 29.4 48.1 79.4 23.0 30.1 61.4 12.6 71.0 30.1 42.4 10.0 26.7 46.9 36.8 70.9 21.3 33.7 38.1 54.0 72.1 35.7 34.4 25.7 71.0 91.8 125.0 47.4 66.5 30.4 53.1 34.7 14.7 33.6 25.1 19.8 34.3 46.1 42.3 21.2 48.5 43.3 22.7 28.1 21.1 51.4 33.2 34.9 58.8 43.8 27.5 93.0 60.1 77.9 38.3 111.0 116.4 44.1 135.4 236.8 72.9 66.6 44.1 275.8 34.0 323.6 138.8 157.7 38.4 32.6 64.9 63.5 83.0 27.2 48.7 89.9 34.8 144.3 7.1 11.8 61.6 74.3 112.6 55.8 199.2 673.8 27.6 10.0 17.7 62.9 19.4 14.6 11.4 23.2 26.3 46.5 17.5 45.0 49.2 114.0 17.0 26.4 63.1 134.3 79.2 57.4 42.5 55.9 20.2 588.7 160.7 77.9 73.3 79.9 26.4 49.0 39.1 332.6 16.5 196.6 0.2 8.4 3.3 2.9 10.0 4.2 6.1 6.1 4.6 0.7 4.1 4.0 2.7 29.8 1.5 7.8 2.8 8.6 7.2 26.5 29.4 23.0 30.1 21.3 33.7 34.4 25.7 30.4 21.2 28.1 27.5 164.0 19.2 7.5 46.4 25.1 20.3 19.7 81.6 18.8 5.0 71.3 44.7 18.9 10.0 54.7 23.9 0.0 6.0 12.4 105.8 5.9 25.8 1.5 19.6 35.2 106.1 25.2 20.2 19.2 56.7 35.0 51.8 20.9 51.8 18.4 35.4 97.1 36.0 3.3 0.0 14.8 13.0 57.0 9.6 14.3 4.2 43.5 17.3 7.2 31.9 25.5 50.4 8.2 13.6 22.5 100.4 106.5 55.3 29.4 34.9 45.7 7.5 24.2 4.4 39.5 72.7 47.5 1.3 5.9 8.5 16.1 10.5 17.9 80.6 21.6 40.8 ECI2 "ACBD2, DRS1, HCA88, PECI" ENSG00000198721 "Enoyl-CoA delta isomerase 2" O75521 6 4115693-4135597 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 422.7" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 293.6;Distal tubular cells: 428.4;Proximal tubular cells: 577.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022130, HPA031626" Enhanced Enhanced Peroxisomes,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Peroxisomes, Mitochondria" "HPA022130: AB_1855176, HPA031626: AB_2673965" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (1.71e-2)" "unprognostic (1.04e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.17e-3)" "unprognostic (4.97e-2)" "unprognostic (9.49e-2)" "unprognostic (3.95e-3)" "unprognostic (3.17e-2)" "unprognostic (5.75e-2)" "prognostic favorable (2.04e-6)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (8.45e-2)" "unprognostic (1.34e-1)" 53.6 123.6 43.9 21.0 47.7 21.5 65.0 46.5 63.7 60.0 50.5 53.3 64.0 44.9 102.1 26.7 49.2 40.1 150.9 42.4 47.8 236.0 422.7 28.6 20.0 45.0 45.6 71.4 159.8 53.2 52.6 37.7 44.2 45.2 55.4 31.8 29.9 36.3 198.4 22.7 59.6 35.5 45.3 30.1 103.5 30.9 49.0 33.5 37.0 236.4 21.8 31.6 26.8 45.5 82.8 45.1 72.8 161.0 89.7 131.4 8.8 114.0 116.7 122.1 107.7 34.0 12.4 3.6 139.6 126.0 111.0 41.6 83.6 67.4 179.5 30.4 95.8 44.0 59.7 186.8 51.3 40.4 20.7 90.6 40.6 106.2 58.4 166.0 262.9 136.2 146.2 31.1 118.6 33.4 113.9 100.7 49.5 8.1 158.7 108.8 90.8 1.5 67.2 16.8 1.8 33.7 6.8 48.2 107.6 131.0 109.8 18.9 268.6 92.4 49.8 82.7 69.8 46.8 88.7 8.4 47.9 34.7 73.0 19.2 36.4 17.4 41.5 28.4 57.1 45.8 48.8 58.3 58.9 51.9 59.8 59.2 1.2 66.0 43.3 45.3 57.9 41.1 43.9 47.7 46.5 63.7 42.4 47.8 45.0 45.6 44.2 45.3 49.0 45.5 61.0 28.9 25.2 17.0 24.4 18.2 48.6 50.3 22.2 14.3 33.3 41.0 165.8 78.6 40.1 36.8 12.5 293.6 29.3 32.0 428.4 53.2 63.1 60.8 43.1 48.0 52.1 77.6 10.7 175.5 29.0 55.2 34.7 57.0 23.4 68.6 53.9 162.2 64.3 18.5 11.9 41.6 20.3 22.0 19.2 50.6 63.3 23.5 35.6 14.0 34.7 77.7 21.6 8.5 18.2 80.4 37.5 50.8 28.3 24.7 120.6 577.0 83.6 46.4 26.3 46.8 33.9 46.5 35.6 24.9 12.8 101.9 41.2 224.0 60.8 22.3 ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 235.8;Endothelial cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 122 "EFO-21: 172.1;HUVEC TERT2: 443.7;TIME: 330.9" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" 62.7 12.7 5.5 11.2 5.5 0.2 59.8 5.7 8.5 26.8 5.3 19.4 4.6 29.4 7.4 15.9 33.5 12.1 54.6 5.2 5.9 29.9 6.0 60.1 11.6 6.0 5.9 10.4 6.7 4.7 7.1 33.5 6.3 19.6 8.0 0.8 16.1 7.3 15.1 16.6 20.7 24.4 6.1 23.5 15.2 3.3 6.7 3.5 40.9 17.2 7.2 35.5 26.1 5.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 172.1 0.3 0.1 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 443.7 0.1 0.0 0.0 1.4 0.0 0.0 0.9 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 330.9 0.4 0.4 0.0 1.7 0.0 0.0 0.2 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.5 5.7 8.5 5.2 5.9 6.0 5.9 6.3 6.1 6.7 5.9 235.8 0.0 3.9 0.0 1.0 14.9 0.4 0.0 0.0 0.0 1.9 2.5 0.0 0.0 0.6 0.0 0.0 0.2 1.0 0.0 0.0 0.6 0.0 0.4 0.5 214.9 0.0 0.0 0.1 1.2 0.1 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.7 10.6 5.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.4 0.0 0.0 1.9 0.0 0.0 0.0 13.9 0.3 1.3 0.9 0.0 1.6 EEA1 ZFYVE2 ENSG00000102189 "Early endosome antigen 1" Q15075 12 92770637-92929331 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005861, CAB018782, HPA038158, HPA038159" Supported Supported Vesicles NA NA 20000 "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB005861: AB_2262056, CAB018782: AB_2277714, HPA038158: AB_10966710, HPA038159: AB_10962356" "unprognostic (5.38e-2)" "unprognostic (4.60e-1)" "unprognostic (2.00e-2)" "unprognostic (5.62e-2)" "unprognostic (1.62e-1)" "unprognostic (1.81e-2)" "unprognostic (6.75e-2)" "unprognostic (6.87e-2)" "unprognostic (1.31e-1)" "unprognostic (5.00e-2)" "unprognostic (2.81e-2)" "unprognostic (1.07e-1)" "unprognostic (2.68e-3)" "unprognostic (5.86e-2)" "unprognostic (2.85e-1)" "unprognostic (3.89e-2)" "unprognostic (1.65e-1)" 11.4 6.6 2.8 6.7 3.0 3.7 7.2 6.6 4.3 9.3 0.0 8.2 6.7 8.7 4.1 13.1 4.8 7.3 7.8 2.7 3.8 6.6 9.5 7.1 5.6 5.3 4.3 8.9 6.0 8.1 2.8 9.4 5.5 7.3 7.0 13.7 7.0 5.7 9.6 10.2 6.6 8.4 3.2 7.3 7.0 5.3 3.5 4.1 8.1 10.4 5.5 8.5 6.8 4.4 14.9 4.9 7.2 5.1 30.1 30.1 16.4 28.8 16.6 15.0 10.6 17.1 4.0 15.2 5.1 20.3 21.3 17.5 16.0 8.1 23.0 10.2 7.8 16.2 5.9 15.7 16.7 11.6 7.3 19.7 11.7 16.1 24.0 16.7 25.3 4.2 12.2 5.0 15.7 6.9 8.4 7.9 7.2 6.0 10.5 9.2 18.2 10.1 7.7 20.4 6.0 4.4 21.2 13.7 12.9 9.9 18.2 10.1 34.4 21.0 8.0 16.8 11.2 5.4 10.1 10.2 7.8 10.1 11.6 0.0 0.6 0.2 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.4 0.8 0.5 0.5 0.2 0.9 0.5 0.1 0.2 2.8 3.0 6.6 4.3 2.7 3.8 5.3 4.3 5.5 3.2 3.5 4.4 58.3 99.3 59.8 60.7 36.4 37.9 57.6 25.2 35.9 53.1 26.5 24.9 93.0 17.2 32.8 25.8 37.5 65.5 39.4 35.7 43.0 59.0 15.1 37.1 85.7 58.9 16.8 14.9 58.5 34.7 45.8 81.1 29.0 53.6 32.9 29.8 31.4 37.4 36.4 183.4 76.2 26.6 14.2 38.6 36.8 9.5 61.8 44.5 48.0 68.4 44.0 60.0 28.8 94.5 102.5 40.4 35.9 68.1 19.8 50.0 26.3 35.3 26.4 68.4 46.0 104.4 71.0 131.1 30.0 91.3 50.3 113.6 29.8 35.5 30.7 78.1 EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.7;Cytotrophoblasts: 1365.8;Fibroblasts: 309.7;Syncytiotrophoblasts: 889.6" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 953.6;hTERT-RPE1: 2226.5;HUVEC TERT2: 4270.9;TIME: 3554.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" 240.5 55.7 57.0 57.2 82.8 0.2 115.3 57.1 88.8 54.9 180.7 74.6 22.5 73.2 128.4 51.5 134.8 140.4 187.8 47.5 75.6 57.4 12.9 150.1 27.2 80.8 121.1 175.1 29.2 17.6 22.6 329.7 65.5 58.4 91.0 42.8 87.7 161.2 14.7 55.2 45.3 93.5 72.2 42.4 46.9 8.0 71.0 16.8 139.1 93.8 21.2 203.9 77.3 71.9 358.4 3.1 8.5 0.3 320.9 217.1 0.8 208.1 233.7 25.2 20.5 0.0 18.0 0.5 140.4 234.3 22.1 323.4 1.6 234.6 8.9 1.0 1.0 0.3 87.4 0.2 843.2 0.3 0.6 953.6 117.5 21.9 260.9 2226.5 4270.9 0.5 1.2 0.2 99.2 36.7 2.6 0.5 4.2 0.1 0.8 0.2 0.3 0.9 9.8 7.3 2.0 0.4 284.6 105.0 0.7 8.1 289.8 1.5 3554.3 1.5 107.5 397.9 138.5 13.7 0.5 1.4 73.1 0.3 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 82.8 57.1 88.8 47.5 75.6 80.8 121.1 65.5 72.2 71.0 71.9 26.6 250.0 109.1 234.1 0.1 79.4 79.1 367.7 42.1 2.8 6.2 78.2 12.5 12.8 98.2 27.6 0.0 1365.8 0.4 0.0 9.8 36.2 0.5 2.2 38.9 73.5 0.0 0.0 1.0 25.6 173.0 309.7 6.1 2.1 2.5 3.9 48.5 0.7 94.9 0.0 4.7 0.0 40.7 0.8 33.9 0.9 42.6 3.2 17.8 6.5 0.6 137.3 0.0 2.5 0.8 2.8 0.0 0.0 1.5 24.2 0.0 14.7 88.8 4.7 0.0 7.0 28.7 0.4 1.8 6.0 31.7 889.6 5.0 61.3 0.0 6.2 EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 806.1;Endothelial cells: 436.5;Hepatic stellate cells: 511.5;Hofbauer cells: 290.3;Spermatogonia: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Cell line enhanced" "Detected in many" "EFO-21: 183.9;HUVEC TERT2: 329.0;RPMI-8226: 136.8;TIME: 312.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" 195.6 50.2 108.8 13.4 90.4 14.4 192.3 85.0 144.3 112.9 74.4 49.1 13.4 104.3 9.8 39.8 98.5 27.4 243.3 89.8 86.5 144.3 56.1 204.2 20.8 102.0 96.9 37.8 28.2 18.5 51.3 181.6 100.9 74.9 3.5 1.0 39.4 13.2 60.5 47.8 51.4 13.4 89.9 191.7 40.7 43.3 111.7 5.6 105.5 25.2 2.9 87.5 86.3 85.2 0.1 45.7 14.6 52.7 1.2 1.0 33.4 12.9 2.3 7.3 2.3 16.2 42.4 0.3 183.9 4.3 11.9 6.5 3.7 8.3 0.3 77.2 14.1 28.8 3.4 1.3 11.4 0.0 40.1 1.5 3.2 3.7 0.0 2.5 329.0 2.1 104.9 0.1 2.5 83.5 0.5 0.7 21.1 64.3 2.6 91.4 5.9 136.8 4.6 1.1 9.3 31.0 6.3 5.9 12.2 4.2 15.5 43.6 312.6 1.8 37.2 4.4 2.5 0.4 0.1 0.5 0.2 0.1 38.4 0.0 2.1 3.5 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.8 0.2 5.5 5.9 0.0 2.4 108.8 90.4 85.0 144.3 89.8 86.5 102.0 96.9 100.9 89.9 111.7 85.2 806.1 0.0 26.5 2.3 6.2 11.9 5.6 5.5 9.6 2.0 5.9 6.7 23.7 5.7 4.2 3.7 0.0 3.1 5.9 1.4 7.9 19.4 2.7 1.4 3.4 436.5 1.2 58.9 15.0 2.0 17.8 18.5 0.5 1.9 20.3 2.0 511.5 20.5 290.3 3.3 10.1 4.6 2.0 24.5 14.2 9.2 8.7 18.7 19.6 102.1 1.2 1.9 0.0 3.5 1.8 5.8 3.7 6.0 4.0 19.1 22.5 25.2 0.2 2.3 13.1 13.0 18.4 18.9 179.8 2.7 9.5 6.0 2.9 4.8 0.5 3.5 EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 189.5;Urothelial cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 103.8;TIME: 172.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Approved "Plasma membrane" NA NA 440000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA052729: AB_2681928, HPA066751: AB_2685713" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.34e-3)" "unprognostic (3.36e-2)" "unprognostic (3.46e-2)" "unprognostic (4.48e-3)" "unprognostic (1.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.74e-1)" "unprognostic (6.93e-2)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.72e-1)" 21.6 4.6 3.1 11.8 3.2 10.9 16.4 7.5 3.5 9.4 5.3 12.1 5.5 9.6 10.5 15.0 9.8 15.2 27.8 3.3 3.8 14.3 9.6 15.0 12.8 4.8 4.0 5.6 14.3 12.8 5.8 8.3 4.8 9.5 10.2 6.1 10.4 9.7 4.4 14.3 12.4 12.9 5.2 7.4 9.9 2.8 4.0 5.3 18.4 4.7 8.8 23.8 9.0 6.6 28.7 9.8 9.3 9.6 4.6 6.5 8.1 14.9 31.4 25.9 36.1 41.4 16.1 5.9 39.2 18.8 51.6 28.4 13.9 32.6 19.0 35.7 11.7 8.7 13.5 7.1 11.3 4.0 24.4 5.5 12.6 26.3 28.8 9.9 103.8 8.7 9.2 6.6 21.1 12.2 4.2 4.5 7.1 27.8 33.5 0.1 24.5 9.4 23.4 57.0 15.4 6.5 10.9 23.2 17.0 9.0 22.9 5.6 172.8 8.1 15.7 30.5 73.1 18.1 30.9 12.4 10.3 9.4 71.6 1.1 14.0 9.0 4.0 12.4 6.1 2.1 6.2 5.0 14.9 2.6 2.6 3.8 2.3 4.4 5.2 2.5 7.9 8.0 3.1 3.2 7.5 3.5 3.3 3.8 4.8 4.0 4.8 5.2 4.0 6.6 94.9 6.4 44.2 3.9 20.0 81.6 189.5 68.1 34.1 4.9 31.4 20.1 36.6 30.0 69.0 44.1 31.3 10.1 22.2 96.0 7.9 71.3 16.1 66.1 9.7 114.9 22.6 5.7 1.2 62.6 20.4 21.3 25.5 72.4 61.6 16.2 54.7 8.7 89.0 1.7 0.7 22.5 28.5 35.6 52.7 34.7 7.5 46.3 19.6 12.2 53.5 37.5 4.1 26.7 2.7 75.1 70.9 4.9 31.5 49.9 71.4 4.6 60.8 27.8 13.1 8.0 29.0 5.4 8.2 29.3 79.8 17.4 27.8 21.2 37.3 200.1 EIF2B2 "EIF-2Bbeta, EIF2B" ENSG00000119718 "Eukaryotic translation initiation factor 2B subunit beta" P49770 14 75002921-75012366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005841, CAB037105, HPA048028" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 12000 "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB037105: AB_1840834, HPA005841: AB_1078725, HPA048028: AB_2680235" "unprognostic (1.10e-1)" "unprognostic (4.41e-2)" "unprognostic (5.70e-2)" "unprognostic (6.71e-2)" "unprognostic (7.64e-2)" "unprognostic (3.45e-3)" "prognostic unfavorable (2.26e-6)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "prognostic favorable (2.95e-4)" "unprognostic (4.15e-2)" "unprognostic (2.74e-1)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" 2.7 5.3 4.0 2.9 4.5 3.2 3.6 8.7 4.8 3.9 2.2 3.0 3.0 3.6 4.9 3.8 3.1 4.0 3.9 3.6 6.1 4.9 3.3 2.7 4.0 4.5 4.2 2.9 4.0 8.5 3.5 4.8 4.5 4.1 3.8 6.8 2.8 4.5 5.5 4.0 2.8 3.4 2.9 2.7 2.6 3.9 4.8 3.9 11.5 7.1 4.2 4.0 2.6 6.9 5.9 7.0 5.6 6.4 6.3 5.2 7.4 3.7 6.1 7.1 8.2 9.0 5.9 5.2 2.3 5.8 4.5 4.4 8.8 8.7 10.6 3.2 6.5 4.6 6.3 6.2 8.2 3.4 5.3 4.8 8.2 9.1 9.3 6.1 24.8 4.5 4.2 4.9 15.5 17.4 5.5 4.3 4.0 7.3 10.3 3.4 6.6 4.3 10.1 7.0 6.0 4.8 3.9 5.5 8.4 6.9 9.0 3.2 6.4 5.4 5.2 2.4 4.8 8.4 7.5 6.2 5.9 4.3 4.2 4.2 1.8 1.4 3.0 1.9 2.5 2.1 2.6 2.5 2.4 2.0 1.9 2.0 1.0 3.3 1.8 2.0 4.0 2.5 4.0 4.5 8.7 4.8 3.6 6.1 4.5 4.2 4.5 2.9 4.8 6.9 18.9 19.2 11.5 6.2 14.1 17.7 19.5 28.9 18.2 28.2 15.4 17.0 18.2 22.8 21.5 25.8 45.9 51.5 16.1 15.3 41.1 36.2 12.1 17.0 14.5 32.1 15.6 20.8 5.3 33.1 56.5 18.3 12.8 12.8 21.5 17.5 13.2 11.9 33.7 28.6 5.4 9.0 20.3 19.1 11.9 12.7 15.8 18.8 14.2 1.9 28.0 27.3 28.8 2.5 8.5 28.1 11.7 16.1 11.3 17.5 19.0 50.8 17.2 29.4 26.3 16.9 27.9 84.2 27.4 27.3 21.9 165.5 14.9 30.5 19.7 19.2 EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Adipocytes: 409.0;Endothelial cells: 261.7;Hepatic stellate cells: 175.3;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" NA NA 470000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA005928: AB_1078735" "unprognostic (8.01e-2)" "unprognostic (2.13e-4)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (2.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (1.03e-4)" "unprognostic (3.65e-1)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-2)" "unprognostic (3.10e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.75e-3)" "unprognostic (2.36e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" 46.3 20.2 6.7 9.6 7.1 0.2 38.2 7.1 11.2 37.1 7.8 10.3 6.8 27.9 9.9 12.7 19.2 31.4 38.5 6.3 7.5 79.7 7.5 48.4 6.6 8.1 7.0 6.9 6.2 19.2 9.6 0.8 9.0 12.7 8.1 1.5 9.2 25.6 18.5 9.0 8.3 38.8 7.0 3.5 8.2 2.3 9.4 8.7 43.6 40.2 4.9 24.9 13.9 7.4 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.1 0.0 30.6 0.0 0.0 0.1 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 7.1 7.1 11.2 6.3 7.5 8.1 7.0 9.0 7.0 9.4 7.4 409.0 6.4 6.0 0.3 14.0 16.6 0.5 0.1 6.2 0.1 2.1 3.0 14.1 0.0 0.7 0.0 0.0 0.1 1.7 0.0 0.0 0.1 0.7 0.6 0.6 261.7 0.0 8.0 1.3 0.0 0.0 16.2 0.0 0.3 0.0 0.1 175.3 1.1 0.2 0.0 0.2 0.0 0.0 5.5 21.4 1.3 1.2 1.7 16.0 111.5 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.4 2.6 1.0 0.0 0.2 0.0 0.4 0.0 5.8 21.4 0.2 0.5 1.1 14.6 0.3 2.4 0.7 0.0 1.0 ENG "CD105, END, HHT1, ORW, ORW1" ENSG00000106991 Endoglin P17813 9 127815013-127854658 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 528.7" "Cell type enhanced" "Detected in many" "Adipocytes: 407.5;Endothelial cells: 514.4;Extravillous trophoblasts: 294.4;Hepatic stellate cells: 579.0;Leydig cells: 487.1;Peritubular cells: 1421.8;Syncytiotrophoblasts: 376.4;Theca cells: 308.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 19.9;intermediate monocyte: 28.2;myeloid DC: 10.3;NK-cell: 7.6;non-classical monocyte: 22.1" "Group enriched" "Detected in many" 4 "dendritic cells: 10.3;monocytes: 28.2;NK-cells: 7.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 263.8;HUVEC TERT2: 487.4;TIME: 1027.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000096, HPA011862, HPA067440, CAB072873" Enhanced Supported "Nuclear bodies,Plasma membrane" NA NA 280000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nuclear bodies" "CAB000096: AB_563482, CAB072873: AB_2665725, HPA011862: AB_1846217, HPA067440: AB_2685840" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "prognostic favorable (6.61e-4)" "prognostic favorable (5.62e-6)" "unprognostic (2.15e-1)" "unprognostic (4.06e-1)" "unprognostic (3.87e-2)" "unprognostic (2.20e-2)" "unprognostic (8.98e-2)" "prognostic unfavorable (4.26e-4)" "unprognostic (3.33e-3)" "unprognostic (7.35e-2)" "unprognostic (2.84e-1)" "unprognostic (1.27e-1)" 234.5 92.6 44.4 80.2 41.5 18.8 164.8 45.2 44.5 129.7 50.4 62.4 33.2 111.1 35.1 43.1 122.4 58.7 528.7 36.7 43.1 211.6 60.7 260.7 43.4 50.0 47.1 220.9 47.1 29.7 56.1 93.6 52.8 93.9 17.5 2.1 46.2 73.5 72.3 51.3 76.8 65.7 43.1 226.5 57.6 98.9 59.4 17.3 169.2 54.8 17.7 93.0 95.8 43.6 1.3 1.0 7.1 0.4 117.8 81.0 217.8 147.1 102.0 74.4 43.4 0.5 1.3 1.0 70.2 263.8 56.8 2.4 0.0 23.2 24.5 0.7 0.3 42.3 76.7 4.6 91.7 20.2 0.5 137.6 5.4 97.7 34.9 1.0 487.4 1.4 0.7 1.4 88.1 0.9 0.6 1.8 1.7 0.3 4.2 66.9 12.5 1.4 0.0 0.4 0.8 1.8 78.0 65.3 20.1 4.7 13.8 29.8 1027.5 248.1 13.7 164.7 0.7 5.2 1.2 0.9 67.1 52.0 83.2 0.0 19.9 0.5 1.8 28.2 0.6 0.6 3.0 3.4 10.3 1.4 1.9 3.0 0.5 7.6 22.1 3.8 1.2 8.4 44.4 41.5 45.2 44.5 36.7 43.1 50.0 47.1 52.8 43.1 59.4 43.6 407.5 3.2 16.0 2.0 9.2 12.0 2.3 2.1 2.8 2.8 9.5 9.8 28.4 18.6 2.3 3.7 4.2 30.0 8.6 0.4 0.0 10.2 8.6 7.7 67.9 514.4 2.4 49.2 0.6 1.1 294.4 85.7 3.1 8.1 15.2 0.8 579.0 9.8 132.0 0.0 0.7 1.6 0.0 65.4 29.7 51.4 487.1 56.6 24.9 78.7 36.2 2.0 4.1 1.5 1.1 1.4 0.0 1421.8 2.1 2.0 0.0 0.3 5.1 4.6 72.3 44.0 57.5 4.4 5.2 1.3 8.4 376.4 9.6 308.1 0.5 1.4 EOGT "AER61, C3orf64, FLJ33770" ENSG00000163378 "EGF domain specific O-linked N-acetylglucosamine transferase" Q5NDL2 3 68975217-69013684 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Peritubular cells: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 86.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019460 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear membrane" Cytosol "HPA019460: AB_1844628" "unprognostic (2.62e-1)" "unprognostic (3.72e-1)" "unprognostic (1.07e-1)" "unprognostic (1.95e-2)" "unprognostic (8.96e-2)" "unprognostic (6.30e-2)" "unprognostic (2.18e-3)" "unprognostic (6.66e-2)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" "unprognostic (1.68e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (8.97e-5)" "unprognostic (7.41e-2)" "unprognostic (4.67e-1)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" 19.4 9.1 7.2 12.8 7.2 5.9 19.5 6.7 10.9 14.0 22.4 25.8 7.4 29.9 9.8 17.5 18.5 17.8 28.5 7.1 7.0 10.2 5.7 28.7 8.2 7.7 7.6 11.6 12.6 5.0 9.3 22.3 8.0 27.9 8.6 8.8 16.4 33.7 20.0 9.7 11.4 25.4 7.8 10.0 15.5 8.9 7.8 11.1 7.9 15.2 8.8 24.7 13.7 7.5 19.0 7.1 12.5 14.4 16.6 32.2 8.6 25.4 31.5 16.0 21.0 9.1 10.2 1.1 3.8 28.1 13.6 6.0 8.3 32.3 19.9 62.3 5.6 20.2 15.5 13.5 18.7 11.5 8.2 26.8 29.4 20.6 25.1 19.4 86.2 0.8 5.9 11.1 53.7 5.5 2.0 3.8 13.5 6.2 3.5 0.8 12.4 8.2 13.9 43.4 1.2 6.3 29.1 1.7 23.5 12.8 6.0 15.9 44.6 40.6 13.4 5.1 24.3 6.0 20.5 9.3 16.3 17.1 23.8 5.4 1.5 0.0 2.0 1.4 2.3 1.1 3.0 4.3 2.4 0.7 2.5 2.7 0.2 2.4 0.5 0.4 6.6 1.3 7.2 7.2 6.7 10.9 7.1 7.0 7.7 7.6 8.0 7.8 7.8 7.5 29.6 12.8 10.3 14.0 3.5 7.1 11.4 13.2 16.5 2.2 7.5 11.7 20.7 4.3 14.5 1.8 16.7 0.9 3.1 5.1 0.0 4.6 16.5 15.3 7.5 23.7 6.0 3.8 11.2 8.2 5.3 9.3 9.2 15.4 0.0 9.4 20.3 3.6 6.7 0.0 21.4 4.5 2.0 6.8 9.8 15.1 3.1 8.6 8.8 30.9 6.5 1.4 1.0 9.5 12.2 12.4 3.4 40.6 5.4 8.3 2.1 1.9 13.2 5.6 0.0 26.8 15.2 5.5 2.5 14.8 4.5 0.8 7.0 6.9 3.4 8.6 EPB41L3 "4.1B, DAL1, KIAA0987" ENSG00000082397 "Erythrocyte membrane protein band 4.1 like 3" Q9Y2J2 18 5392381-5630700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 171.9;Excitatory neurons: 306.8;Inhibitory neurons: 237.4;Late spermatids: 291.6;Oligodendrocytes: 159.2;Syncytiotrophoblasts: 214.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.7;non-classical monocyte: 12.4" "Lineage enriched" "Detected in many" 5 "monocytes: 12.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 62.8;HUVEC TERT2: 59.5;SCLC-21H: 65.5;TIME: 164.8;U-2 OS: 57.7;U-2197: 57.1;U-251 MG: 71.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028605 Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 100000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "HPA028605: AB_10611963" "unprognostic (3.58e-3)" "unprognostic (1.17e-2)" "unprognostic (3.61e-1)" "unprognostic (7.97e-2)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (2.60e-1)" "unprognostic (9.73e-2)" "unprognostic (3.40e-1)" "unprognostic (3.63e-3)" "unprognostic (1.07e-3)" "unprognostic (5.81e-2)" "unprognostic (5.96e-2)" "unprognostic (5.65e-3)" "unprognostic (8.99e-2)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" 27.6 28.1 5.8 27.4 5.3 4.1 11.7 17.9 49.9 6.4 0.0 17.7 49.6 7.8 5.6 10.7 13.6 9.3 6.5 7.1 24.8 33.9 4.8 13.9 7.9 59.6 14.7 11.4 6.9 59.6 10.4 21.1 53.3 5.8 13.1 45.8 4.0 7.3 6.1 4.0 47.7 13.4 7.7 12.2 3.2 62.3 29.1 6.5 4.6 10.7 3.9 10.3 5.7 29.8 0.3 0.9 3.9 0.0 54.5 62.8 43.7 12.8 0.0 0.0 0.0 0.7 0.1 0.1 0.1 39.8 23.2 0.2 38.6 0.0 0.0 0.0 34.2 0.1 0.4 0.0 0.2 0.1 4.6 33.3 0.0 12.3 0.1 16.2 59.5 0.0 0.4 0.4 0.1 0.0 0.5 0.7 7.9 0.2 12.5 0.3 0.0 0.2 0.4 4.8 65.5 0.5 0.1 0.5 25.9 31.2 0.7 4.8 164.8 0.3 57.7 57.1 71.6 0.1 0.1 0.0 0.2 5.4 6.8 0.0 4.3 0.0 0.0 7.7 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.7 0.0 12.4 0.0 0.0 0.7 5.8 5.3 17.9 49.9 7.1 24.8 59.6 14.7 53.3 7.7 29.1 29.8 18.2 19.2 6.4 28.7 1.3 15.9 4.1 0.0 3.4 75.6 5.3 1.7 3.5 2.8 1.9 7.3 77.2 98.6 0.2 44.0 15.6 0.4 171.9 2.2 10.1 21.9 9.1 3.2 306.8 0.7 44.2 27.7 0.0 2.1 0.0 0.0 7.1 0.8 58.8 3.3 237.4 10.0 0.0 82.2 66.7 291.6 22.4 81.9 10.6 103.0 50.9 3.3 2.1 44.2 159.2 0.8 8.3 7.9 1.6 3.8 91.2 68.4 1.6 14.7 0.0 3.0 13.1 2.7 11.5 2.3 8.4 214.0 2.6 0.2 12.3 1.7 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3" "Cell type enhanced" "Detected in many" "Ductal cells: 45.1;Enteroendocrine cells: 48.7;Intestinal goblet cells: 61.1;Oligodendrocytes: 76.3;Pancreatic endocrine cells: 63.7;Undifferentiated cells: 97.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 86.5;HUVEC TERT2: 74.2;TIME: 79.2;U-251 MG: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" No No 380000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.1 1.6 2.1 9.2 3.7 0.5 1.6 4.1 4.2 2.5 0.0 22.6 21.0 1.8 1.9 0.6 4.4 3.7 3.3 2.2 4.3 3.8 0.4 1.8 2.9 5.7 4.5 10.6 3.9 6.1 2.9 4.0 4.8 1.9 23.3 2.9 1.5 3.0 0.2 0.9 21.8 3.3 5.0 2.4 1.7 1.8 5.4 1.2 7.3 0.3 1.7 4.4 1.0 8.2 43.4 17.2 17.2 27.7 1.6 1.5 0.0 10.0 0.5 27.3 5.7 6.3 16.6 0.6 20.2 4.0 86.5 39.6 10.8 52.8 7.7 0.1 4.1 0.0 1.9 0.1 16.5 0.0 4.3 5.3 17.5 48.7 0.3 25.4 74.2 2.4 1.8 0.1 5.7 6.4 1.1 0.3 4.0 49.0 11.2 5.3 18.0 0.8 14.7 4.0 18.0 19.3 17.4 0.7 0.2 1.5 1.1 0.5 79.2 11.5 29.6 29.4 69.5 0.0 0.2 0.1 21.8 0.9 0.5 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 3.7 4.1 4.2 2.2 4.3 5.7 4.5 4.8 5.0 5.4 8.2 0.4 3.2 0.0 5.5 0.3 0.8 1.7 20.5 0.0 15.4 0.1 0.1 1.3 7.2 8.6 0.0 0.0 0.5 0.1 24.3 0.0 45.1 2.6 1.0 0.8 1.2 48.7 0.0 34.1 8.0 2.8 5.0 1.1 2.4 0.0 0.5 0.4 0.4 9.6 6.7 32.3 61.1 6.1 7.6 1.4 0.8 0.9 7.2 0.0 21.5 0.7 18.4 0.0 5.5 76.3 63.7 12.6 0.7 0.3 2.3 5.5 0.2 1.7 1.8 0.0 0.6 2.1 0.5 3.5 0.0 0.4 1.1 0.3 0.2 97.2 1.1 EPHB4 "HTK, Tyro11" ENSG00000196411 "EPH receptor B4" P54760 7 100802565-100827523 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Angiogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 68.5;Hepatic stellate cells: 113.2;Syncytiotrophoblasts: 206.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.0;neutrophil: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB013537 Uncertain NA NA 1400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB013537: " "prognostic unfavorable (8.56e-4)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.33e-1)" "unprognostic (5.23e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.84e-1)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (9.51e-3)" "unprognostic (6.63e-2)" "unprognostic (3.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (8.84e-4)" 26.4 49.8 5.0 8.0 4.3 5.6 32.6 4.6 4.8 45.6 6.8 20.7 8.3 61.5 3.8 24.7 27.1 18.0 26.1 4.1 4.1 28.3 33.3 28.2 5.8 5.5 5.1 36.0 26.8 10.1 6.3 35.5 5.3 28.9 10.2 0.3 24.2 22.4 7.7 35.8 17.5 22.2 5.1 47.9 21.4 12.3 6.3 3.1 17.6 13.3 4.9 17.3 28.1 4.8 37.7 33.1 32.5 94.2 20.4 13.0 94.7 14.1 31.2 22.3 29.0 27.4 28.3 4.8 63.6 15.3 31.3 38.2 14.3 38.3 11.9 6.2 25.6 1.3 19.0 43.2 11.8 0.7 0.9 15.3 56.7 14.2 33.1 24.8 84.0 1.5 71.9 1.8 18.4 66.4 0.7 15.0 54.7 56.3 47.5 51.4 15.6 8.9 28.6 19.9 0.2 27.4 22.0 10.4 22.1 45.1 26.1 6.7 71.3 27.6 42.6 51.3 21.4 0.2 0.8 1.7 4.0 12.0 51.2 0.0 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 4.3 0.0 0.1 0.1 0.0 0.7 5.0 4.3 4.6 4.8 4.1 4.1 5.5 5.1 5.3 5.1 6.3 4.8 47.1 9.6 12.6 1.6 1.9 20.5 10.3 13.9 15.9 0.1 22.0 19.7 5.7 7.2 8.5 5.5 0.0 68.5 1.1 9.1 0.0 12.3 28.5 4.8 21.8 51.2 3.0 10.8 0.3 6.6 11.2 6.5 12.8 8.0 1.3 10.7 113.2 22.4 9.0 0.0 0.2 17.4 8.2 4.1 3.4 9.9 8.1 1.3 3.6 1.9 1.5 1.7 0.0 0.0 1.0 20.6 7.6 4.1 1.4 13.3 1.3 4.0 4.2 0.2 6.6 5.7 6.3 1.4 10.2 12.1 17.8 206.5 1.2 2.9 19.9 8.0 ERAP2 "L-RAP, LRAP" ENSG00000164308 "Endoplasmic reticulum aminopeptidase 2" Q6P179 5 96875986-96919703 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 176.1;GAMG: 105.0;hTEC/SVTERT24-B: 83.2;MOLT-4: 98.8;TIME: 188.7" "Low region specificity" "Detected in all" "CAB025618, HPA034498, HPA064360" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 11000000 "Cluster 15: NK-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "CAB025618: , HPA034498: AB_2674191, HPA064360: " "unprognostic (4.62e-2)" "unprognostic (1.60e-1)" "unprognostic (4.98e-2)" "unprognostic (1.56e-1)" "unprognostic (3.14e-1)" "unprognostic (8.71e-2)" "unprognostic (2.60e-2)" "unprognostic (1.17e-2)" "unprognostic (5.03e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.01e-1)" "unprognostic (9.54e-3)" "unprognostic (6.59e-2)" "unprognostic (8.48e-2)" "unprognostic (4.65e-2)" "unprognostic (3.05e-1)" 7.8 7.1 3.0 31.5 3.0 7.5 11.9 2.3 4.3 12.2 3.0 16.2 32.6 8.4 17.5 10.5 7.0 11.0 7.5 2.9 2.5 11.3 14.5 18.1 46.4 4.3 3.3 8.5 2.9 3.7 3.6 11.0 3.5 10.3 6.2 2.3 6.6 7.0 8.9 10.1 21.5 3.4 2.7 36.7 19.0 1.7 3.8 49.9 5.6 9.9 29.7 14.7 6.8 3.5 2.1 2.4 1.7 0.9 1.9 3.8 0.6 8.1 13.8 7.3 12.3 7.9 176.1 12.2 35.1 11.5 105.0 2.9 0.9 65.4 5.8 4.3 7.9 0.6 3.0 8.5 2.7 43.2 19.2 25.3 12.8 83.2 0.6 1.2 4.9 27.4 0.2 25.8 20.8 1.4 98.8 22.5 0.2 0.0 3.7 45.7 16.2 29.3 55.2 15.4 3.5 0.2 1.1 0.9 16.5 0.4 6.5 1.7 188.7 3.9 1.1 10.0 24.6 26.2 23.2 4.2 50.8 5.8 0.9 23.0 12.1 15.4 24.8 27.5 31.3 28.5 34.6 30.6 19.8 17.7 37.4 28.9 4.2 45.4 28.5 6.9 34.6 27.6 3.0 3.0 2.3 4.3 2.9 2.5 4.3 3.3 3.5 2.7 3.8 3.5 46.7 32.1 20.0 11.8 62.6 5.7 11.2 24.4 12.0 1.5 3.1 5.8 4.4 8.6 15.9 44.1 0.0 11.5 35.6 48.1 0.0 5.3 0.3 7.0 10.6 34.1 1.8 15.8 2.5 25.5 17.0 23.4 17.3 7.4 7.0 33.4 31.4 16.3 12.3 0.0 2.1 23.3 8.2 29.4 14.2 0.7 10.5 33.0 7.2 21.5 19.4 6.5 20.6 7.1 4.9 22.1 27.6 7.9 56.0 4.3 52.4 6.2 15.7 2.8 0.0 12.2 12.2 0.9 0.8 10.0 3.0 6.7 54.2 9.3 34.2 10.5 ERCC6 "ARMD5, CKN2, CSB, RAD26" ENSG00000225830 "ERCC excision repair 6, chromatin remodeling factor" "P0DP91, Q03468" 10 49454168-49539538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Age-related macular degeneration, Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Mental retardation, Premature ovarian failure, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 53.8;hTERT-RPE1: 123.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071297 Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies" "HPA071297: AB_2732177" "unprognostic (1.92e-2)" "unprognostic (1.85e-1)" "unprognostic (9.79e-3)" "unprognostic (7.26e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-2)" "unprognostic (3.03e-2)" "unprognostic (2.99e-2)" "unprognostic (1.71e-2)" "unprognostic (1.13e-1)" "unprognostic (1.80e-1)" "unprognostic (4.57e-2)" "unprognostic (1.04e-1)" "unprognostic (8.61e-2)" "unprognostic (4.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" 2.7 2.1 1.6 1.9 1.5 4.6 3.8 3.0 2.3 3.1 7.7 2.4 2.0 3.0 1.5 3.8 2.9 2.7 3.4 1.2 1.1 3.2 3.3 2.7 2.9 2.4 1.9 4.5 3.1 5.9 2.8 3.4 2.1 3.3 2.7 3.1 3.2 2.2 3.5 4.6 2.5 2.3 2.2 2.9 2.4 3.1 2.1 3.3 5.1 3.6 3.4 2.6 3.3 1.9 11.2 5.5 4.1 2.1 6.6 10.5 3.4 21.2 27.1 14.1 9.9 6.2 5.6 4.9 3.7 18.7 6.7 9.5 6.3 16.6 13.5 8.4 4.1 3.9 21.7 3.4 3.9 5.0 3.7 4.3 17.2 12.9 53.8 123.4 19.8 2.9 6.8 0.8 16.8 8.3 3.4 2.0 4.0 3.5 10.2 2.3 5.8 2.6 4.1 7.1 5.9 4.7 15.4 3.6 8.2 9.4 7.1 2.7 38.9 7.0 5.5 8.6 5.2 3.3 4.5 4.1 7.3 5.0 5.1 13.1 3.0 7.5 4.1 2.6 3.0 6.8 2.3 2.2 3.9 5.2 2.8 1.4 7.2 1.2 5.3 2.2 3.1 1.8 1.6 1.5 3.0 2.3 1.2 1.1 2.4 1.9 2.1 2.2 2.1 1.9 6.9 16.0 13.2 14.7 6.0 3.6 1.4 1.5 5.2 0.0 7.1 7.1 7.1 5.7 8.2 9.2 0.0 2.5 10.9 4.8 5.9 5.2 11.3 8.1 8.7 5.1 1.2 1.3 24.3 6.0 2.1 4.9 2.0 10.1 7.6 8.9 5.3 4.3 2.6 0.0 21.7 5.3 0.0 4.4 2.6 15.3 2.8 8.0 1.8 23.4 11.2 0.0 4.1 17.6 16.6 5.2 2.6 2.2 3.6 2.5 5.0 3.6 9.0 0.0 6.6 4.4 4.2 5.3 5.0 3.5 4.1 1.8 7.4 11.4 2.8 1.9 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 405.9;Endothelial cells: 301.0;Hepatic stellate cells: 138.1;Sertoli cells: 151.2;Smooth muscle cells: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Group enriched" "Detected in many" 10 "HEL: 218.8;HUVEC TERT2: 277.9;TIME: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" 97.5 17.7 38.4 9.0 37.7 1.9 79.4 38.8 46.9 33.3 30.1 20.0 7.0 36.2 7.8 21.8 34.2 20.0 83.0 35.2 38.7 63.6 11.5 112.5 8.7 40.9 38.9 14.4 13.6 13.2 14.8 106.9 44.0 19.8 7.8 2.5 15.6 15.6 27.1 18.2 20.9 29.4 37.3 17.3 23.4 4.3 45.4 5.4 95.9 49.8 8.3 30.8 30.2 37.8 1.2 1.6 0.4 1.2 0.0 0.3 5.1 0.1 0.1 0.0 0.1 2.7 14.1 1.2 3.2 0.0 0.2 0.0 3.7 0.0 0.0 1.8 1.3 218.8 0.1 8.0 0.6 0.4 3.6 0.0 0.0 0.0 0.0 0.2 277.9 0.1 0.2 5.9 0.5 1.8 0.0 0.0 0.6 20.8 2.1 0.0 1.0 0.9 0.0 2.4 0.2 0.8 0.1 16.1 0.0 7.5 3.3 0.8 142.0 0.4 0.4 0.5 0.0 0.2 0.2 0.2 0.1 0.5 0.4 8.2 0.6 0.0 0.1 0.3 0.0 2.1 1.5 0.1 0.4 7.5 2.2 0.8 6.5 0.0 0.0 0.4 0.4 24.8 38.4 37.7 38.8 46.9 35.2 38.7 40.9 38.9 44.0 37.3 45.4 37.8 405.9 38.5 56.0 2.0 4.5 15.2 0.5 0.2 2.8 18.5 2.5 3.2 11.2 0.0 3.0 14.7 4.2 1.8 2.5 3.5 5.9 7.6 5.0 1.1 1.5 301.0 0.0 5.3 1.5 2.4 18.7 13.8 3.6 1.4 3.8 0.1 138.1 1.7 1.1 0.0 0.4 0.4 0.0 5.3 22.1 26.3 0.9 25.7 12.4 20.6 1.2 0.7 0.0 0.5 0.4 46.5 2.1 0.4 2.8 1.8 0.1 0.1 1.9 1.3 151.2 4.6 89.4 0.1 0.9 0.8 10.9 37.1 2.0 2.4 1.6 2.3 ESM1 ENSG00000164283 "Endothelial cell specific molecule 1" Q9NQ30 5 54977867-55022671 "Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 19.9;thyroid gland: 17.3" "Cell type enriched" "Detected in some" 8 "Endothelial cells: 142.4" "Cancer enriched" "Detected in all" 8 "renal cancer: 65.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "NK-cell: 1.4" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 302.2;TIME: 568.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB047364 Approved "Secreted to blood" NA NA 1540000 340000 "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB047364: " "unprognostic (4.70e-2)" "prognostic unfavorable (2.11e-7)" "unprognostic (2.63e-3)" "unprognostic (2.31e-3)" "unprognostic (4.68e-2)" "unprognostic (1.55e-1)" "unprognostic (6.85e-3)" "unprognostic (1.59e-2)" "unprognostic (1.05e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (4.00e-4)" "unprognostic (7.77e-2)" "unprognostic (1.09e-1)" "unprognostic (7.84e-2)" "unprognostic (2.94e-1)" 1.3 4.2 0.4 0.7 0.7 0.6 0.5 0.2 1.1 2.0 0.8 0.2 0.7 3.6 0.4 0.2 0.2 1.3 3.6 0.3 1.3 19.9 2.6 11.3 1.2 0.5 0.5 0.7 2.3 6.0 2.2 0.4 0.3 3.5 0.0 0.1 6.3 3.7 0.2 0.1 0.8 0.7 0.8 0.9 0.3 0.6 1.6 0.2 17.3 0.2 0.6 1.3 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 79.8 9.5 4.1 1.0 0.0 0.0 0.1 7.4 5.7 2.3 0.0 0.0 1.0 14.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.7 0.4 8.5 302.2 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 568.0 4.7 13.7 39.2 21.3 0.1 0.0 0.0 1.7 0.0 3.8 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.1 0.4 0.7 0.2 1.1 0.3 1.3 0.5 0.5 0.3 0.8 1.6 0.4 6.3 0.0 0.6 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.0 16.1 0.0 0.1 0.1 142.4 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.0 0.7 0.0 2.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.5 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 1.5 1.7 0.1 0.3 0.0 0.1 0.1 0.6 1.1 0.0 0.7 ESX1 "ESX1L, ESXR1" ENSG00000123576 "ESX homeobox 1" Q8N693 X 104250038-104254933 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "testis: 8.9" "Cell type enriched" "Detected in some" 25 "Spermatogonia: 98.0" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "TIME: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA051992, HPA073330" Enhanced Supported "Nuclear speckles" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA051992: AB_2681684, HPA073330: " "unprognostic (1.87e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 98.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 EVA1C "B18, B19, C21orf63, C21orf64, FAM176C, PRED34" ENSG00000166979 "Eva-1 homolog C" P58658 21 32412006-32515397 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 156.1;Late spermatids: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.1;gdT-cell: 3.1;MAIT T-cell: 3.8;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.2;naive CD8 T-cell: 1.6;NK-cell: 3.2" "Group enriched" "Detected in many" 7 "granulocytes: 1.1;NK-cells: 3.2;T-cells: 3.8" "Cell line enhanced" "Detected in many" "A549: 24.5;CAPAN-2: 22.4;HBEC3-KT: 18.1;hTCEpi: 18.1;HUVEC TERT2: 18.7;SK-MEL-30: 19.1;U-87 MG: 19.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015720, HPA029944, CAB034174" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB034174: AB_1564317, HPA015720: AB_1845705, HPA029944: AB_10601092" "unprognostic (7.55e-3)" "unprognostic (8.91e-3)" "unprognostic (5.51e-2)" "unprognostic (2.55e-1)" "unprognostic (3.16e-2)" "prognostic favorable (5.06e-4)" "unprognostic (1.40e-3)" "unprognostic (4.24e-3)" "unprognostic (3.39e-1)" "unprognostic (2.65e-2)" "unprognostic (1.65e-1)" "unprognostic (3.84e-2)" "unprognostic (3.29e-2)" "unprognostic (1.08e-1)" "unprognostic (2.73e-1)" "unprognostic (5.95e-3)" "unprognostic (4.25e-3)" 25.8 3.1 4.9 3.7 5.6 1.1 20.4 5.3 6.4 14.0 5.3 11.6 1.3 22.1 6.3 11.1 23.9 11.9 13.5 4.7 5.8 6.8 2.0 17.3 4.7 5.8 5.5 12.5 5.2 7.2 7.6 7.1 5.7 20.0 2.4 0.4 14.4 22.0 6.1 18.5 6.7 13.0 4.9 5.8 9.7 9.6 6.0 2.3 10.6 5.2 8.9 18.4 17.1 6.4 0.0 24.5 0.1 1.1 7.2 4.1 0.4 4.5 2.2 1.5 0.5 0.0 22.4 0.1 0.3 0.2 2.3 0.0 0.7 18.1 0.5 2.2 0.0 0.0 10.9 0.6 6.7 0.0 0.0 1.5 18.1 3.4 13.2 3.8 18.7 1.7 0.0 0.0 1.8 0.1 0.1 0.0 0.8 1.1 4.4 0.0 0.4 0.0 0.4 0.3 6.8 1.1 13.4 1.0 19.1 0.1 0.8 0.0 15.4 1.9 0.5 2.6 1.0 0.3 0.1 0.1 19.9 0.1 5.6 1.1 0.0 0.0 3.1 0.1 3.8 0.0 3.2 3.2 0.1 0.0 0.6 1.6 0.0 3.2 0.3 0.0 0.4 1.2 4.9 5.6 5.3 6.4 4.7 5.8 5.8 5.5 5.7 4.9 6.0 6.4 77.1 19.2 16.0 19.9 1.3 42.7 94.3 156.1 83.6 6.8 22.4 32.4 7.1 42.9 72.2 9.2 0.0 0.3 14.4 3.3 0.0 77.7 84.6 22.6 62.9 68.8 1.8 19.4 24.6 10.2 0.2 18.5 12.2 12.3 6.3 1.1 36.8 1.4 0.5 6.7 37.6 4.8 10.2 1.9 21.3 227.2 14.6 4.9 23.2 49.6 3.1 28.2 16.5 32.6 86.3 8.2 2.6 14.7 6.6 53.6 7.5 2.3 70.0 2.0 19.7 9.4 27.5 15.2 2.1 22.0 29.5 0.7 13.0 0.2 6.8 60.0 EXOC1 "BM-102, FLJ10893, SEC3, SEC3L1, Sec3p" ENSG00000090989 "Exocyst complex component 1" Q9NV70 4 55853648-55905086 "Predicted intracellular proteins, Transporters" "Antiviral defense, Exocytosis, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037706, HPA044873" Uncertain Approved "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Microtubules, Cytosol" "HPA037706: AB_10670525, HPA044873: AB_2679125" "unprognostic (7.10e-3)" "unprognostic (4.48e-2)" "unprognostic (8.85e-2)" "unprognostic (9.22e-2)" "unprognostic (9.81e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.63e-4)" "unprognostic (2.84e-3)" "unprognostic (4.65e-2)" "unprognostic (2.04e-2)" "unprognostic (4.03e-3)" "unprognostic (1.55e-1)" "unprognostic (1.94e-1)" "unprognostic (3.11e-1)" "unprognostic (2.93e-2)" "unprognostic (6.24e-2)" "prognostic favorable (5.50e-5)" 19.7 16.5 18.1 17.3 20.4 12.7 20.0 20.4 20.0 18.9 18.7 18.0 16.8 16.6 20.4 29.3 16.5 15.5 16.5 18.3 20.0 15.9 10.2 17.4 18.3 21.1 19.2 15.1 12.9 20.5 14.5 20.8 20.3 14.3 19.1 18.5 17.4 12.8 13.6 28.1 16.2 15.7 20.4 20.8 15.6 16.9 20.1 13.9 16.3 13.5 20.0 16.2 20.1 25.1 21.8 12.4 21.9 25.3 36.9 45.9 14.6 30.2 30.1 24.1 25.1 8.6 37.1 20.9 20.6 32.6 29.1 25.4 18.0 23.9 34.5 11.1 12.4 19.4 14.8 10.1 34.7 21.3 26.4 37.4 32.1 25.1 27.6 31.2 39.9 16.0 28.3 20.1 53.0 13.8 15.6 21.5 13.9 31.2 23.4 18.0 16.4 17.1 26.9 23.6 16.2 28.7 18.0 29.2 25.5 18.5 18.6 22.6 48.5 29.7 24.2 25.8 26.3 23.9 12.7 18.4 38.6 23.4 28.8 21.3 14.6 13.1 6.5 19.0 8.8 8.4 9.2 9.5 14.3 8.3 8.3 6.0 19.5 12.5 23.6 6.4 11.6 7.9 18.1 20.4 20.4 20.0 18.3 20.0 21.1 19.2 20.3 20.4 20.1 25.1 44.7 41.7 38.0 77.4 24.5 34.8 14.8 34.0 22.2 48.8 26.4 21.2 29.1 17.2 35.6 22.0 31.3 60.8 21.4 38.3 19.6 23.6 45.3 41.0 47.5 39.0 22.2 19.6 72.6 20.0 31.6 28.9 22.4 37.2 36.7 35.5 40.0 12.3 40.9 28.6 86.5 28.8 24.4 37.7 47.4 16.7 21.5 37.8 40.9 56.2 38.7 40.3 22.6 73.4 138.0 36.2 32.4 23.7 19.0 17.4 37.6 21.9 44.7 32.5 32.9 25.9 27.9 47.6 31.6 42.5 39.9 51.2 27.8 44.6 28.7 26.8 EXOC6 "DKFZp761I2124, EXOC6A, FLJ1125, MGC33397, SEC15L, SEC15L1, Sec15p" ENSG00000138190 "Exocyst complex component 6" Q8TAG9 10 92826831-93059493 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 164.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 181.7;Microglial cells: 146.1;Oligodendrocyte precursor cells: 157.3;Rod photoreceptor cells: 177.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036285, HPA059111" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA036285: AB_10673617, HPA059111: AB_2683907" "unprognostic (1.41e-1)" "unprognostic (1.39e-3)" "unprognostic (5.20e-2)" "unprognostic (2.65e-1)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (1.16e-3)" "unprognostic (7.21e-3)" "unprognostic (3.84e-1)" "unprognostic (2.70e-1)" "unprognostic (1.66e-1)" "unprognostic (8.13e-2)" "prognostic favorable (4.66e-4)" "unprognostic (2.12e-2)" "unprognostic (1.00e-1)" "unprognostic (1.42e-1)" "unprognostic (6.41e-2)" 8.7 14.4 5.9 8.2 7.5 12.9 8.0 7.7 8.6 6.5 8.0 9.6 8.1 6.1 5.7 4.2 5.8 10.1 7.1 8.2 6.0 6.4 10.1 10.7 9.5 3.4 2.4 3.9 10.0 6.3 6.1 37.4 3.7 8.6 10.2 164.2 5.6 4.3 31.8 5.0 9.5 7.7 3.3 9.1 7.0 9.9 6.1 8.5 28.4 19.7 8.2 10.1 3.5 7.1 19.8 24.3 25.7 16.8 1.3 1.6 9.1 9.0 24.9 8.1 9.7 9.1 16.5 22.5 19.0 4.3 6.6 12.3 20.8 5.7 10.1 20.1 20.9 35.1 8.3 11.7 9.6 36.4 30.6 2.2 3.0 7.2 4.8 14.6 113.8 14.6 29.2 14.5 4.0 10.7 15.3 23.2 3.5 40.2 7.0 22.5 11.2 11.6 17.4 13.2 8.5 11.9 9.2 9.2 11.8 6.4 18.2 18.8 22.4 0.6 8.2 7.5 14.7 10.8 12.4 18.1 2.8 41.6 9.3 6.2 4.9 15.2 3.0 3.9 3.0 6.7 3.4 2.8 5.1 6.6 2.7 3.2 30.6 2.8 3.9 11.1 3.3 2.4 5.9 7.5 7.7 8.6 8.2 6.0 3.4 2.4 3.7 3.3 6.1 7.1 28.3 16.0 16.7 33.6 27.6 3.3 10.7 8.6 3.4 40.2 9.8 6.5 12.0 20.0 15.0 16.5 39.6 22.9 24.1 14.3 5.9 28.3 5.4 8.8 3.0 53.1 25.6 39.2 181.7 15.4 7.8 7.8 13.7 16.5 10.8 24.3 77.1 14.2 21.4 23.5 100.3 16.6 14.2 18.2 12.5 12.6 4.4 18.9 5.4 146.1 22.8 27.1 19.6 157.3 84.7 14.1 10.3 14.7 13.8 14.1 10.8 8.4 10.0 177.8 13.1 13.6 9.0 25.0 25.5 4.9 4.8 20.5 18.4 29.8 11.9 15.8 F11R "CD321, JAM-1, JAM-A, JAM1, JAMA, JCAM, PAM-1" ENSG00000158769 "F11 receptor" Q9Y624 1 160995211-161021343 "CD markers, Plasma proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 253.2;Urothelial cells: 242.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 165.5;neutrophil: 113.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 165.5" "Cell line enhanced" "Detected in many" "HaCaT: 205.4;OE19: 202.4;SuSa: 232.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004671, HPA043616, HPA061700" Enhanced Supported "Cell Junctions,Microtubules" NA NA 1900000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Microtubules "Cell Junctions" "CAB004671: AB_425964, HPA043616: , HPA061700: AB_2684589" "unprognostic (1.60e-2)" "unprognostic (5.78e-3)" "unprognostic (1.78e-3)" "unprognostic (2.24e-1)" "unprognostic (4.99e-2)" "unprognostic (4.89e-2)" "unprognostic (2.28e-1)" "unprognostic (2.55e-1)" "unprognostic (6.35e-2)" "unprognostic (1.98e-3)" "unprognostic (1.87e-2)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (2.50e-1)" "unprognostic (1.59e-1)" "unprognostic (9.72e-3)" "unprognostic (5.01e-2)" 21.1 24.5 6.6 20.8 6.3 21.3 26.8 6.0 8.2 24.2 9.6 52.6 55.9 11.9 21.1 85.5 33.1 28.7 12.8 6.3 6.5 40.4 73.6 67.1 13.2 7.8 7.5 14.0 41.7 36.3 18.8 50.7 7.5 28.7 51.7 2.2 49.4 21.2 6.1 48.2 64.0 9.0 7.2 21.5 52.6 13.0 8.6 16.5 39.2 6.3 32.0 52.2 44.1 7.1 122.9 15.5 4.7 1.4 3.3 0.2 95.5 0.6 0.1 4.0 4.1 113.5 155.9 8.9 78.6 0.2 22.6 205.4 25.3 105.2 6.4 6.9 17.8 25.8 6.2 52.3 4.8 24.2 72.6 1.4 132.5 0.6 32.7 24.1 98.6 18.8 35.6 2.5 0.6 53.5 7.6 13.6 80.1 202.4 21.9 11.3 0.0 39.2 67.2 94.4 34.3 8.8 29.2 123.4 26.2 232.8 132.6 41.7 58.8 0.3 3.0 0.4 1.2 28.2 59.3 3.1 18.0 23.4 7.5 34.6 31.0 165.5 12.6 16.3 6.7 4.7 11.7 8.0 24.6 2.9 11.1 8.8 113.4 8.2 13.0 18.7 5.7 25.1 6.6 6.3 6.0 8.2 6.3 6.5 7.8 7.5 7.5 7.2 8.6 7.1 27.7 253.2 137.2 0.0 9.8 35.2 119.7 86.2 64.3 0.9 35.0 15.5 3.3 67.2 136.2 77.3 2.1 78.6 10.2 154.9 7.9 76.8 7.2 120.8 13.9 41.5 62.2 10.3 2.7 71.0 176.2 9.1 66.8 150.9 18.3 13.7 34.2 68.8 31.0 0.0 1.1 71.5 46.8 14.4 25.5 2.1 2.1 24.7 8.8 7.5 48.7 1.5 13.4 3.0 0.4 91.4 114.1 0.7 10.8 135.3 82.5 12.6 178.8 2.4 0.0 5.1 6.2 13.4 2.9 102.3 50.6 63.1 12.3 8.1 50.7 242.0 FAM107A "DRR1, TU3A" ENSG00000168309 "Family with sequence similarity 107 member A" O95990 3 58564117-58627610 "Predicted intracellular proteins" "Cell cycle, Growth regulation, Stress response" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 1923.8;choroid plexus: 1389.1" "Cell type enhanced" "Detected in many" "Adipocytes: 196.3;Astrocytes: 81.9;Endothelial cells: 121.3;Hepatic stellate cells: 150.6;Muller glia cells: 125.0" "Cancer enriched" "Detected in many" 6 "glioma: 110.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 20.7;HUVEC TERT2: 64.9" "Low region specificity" "Detected in all" HPA055888 Enhanced Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA055888: AB_2682957" "unprognostic (1.20e-2)" "unprognostic (1.19e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.11e-1)" "unprognostic (7.80e-3)" "prognostic favorable (3.38e-4)" "unprognostic (1.92e-1)" "unprognostic (1.64e-1)" "unprognostic (5.73e-2)" "unprognostic (7.82e-3)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (1.33e-2)" "unprognostic (2.82e-1)" "unprognostic (1.92e-1)" "unprognostic (7.95e-3)" 73.2 7.5 1824.7 8.3 1801.2 0.3 58.6 1490.8 1923.8 34.5 1389.1 36.9 5.4 36.3 53.3 29.2 87.0 16.0 140.4 1745.7 1736.7 45.0 5.5 93.2 3.1 1611.9 1644.5 11.8 23.3 5.9 109.6 29.4 1613.0 80.5 16.0 85.1 40.6 38.0 26.3 23.3 45.2 42.5 1564.5 25.7 37.7 5.7 1698.7 43.9 51.4 32.8 8.6 68.9 41.6 1770.4 0.0 0.0 0.9 0.0 20.7 1.3 0.3 0.1 0.0 0.1 0.2 0.0 0.1 0.1 5.8 0.0 0.2 0.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 1.4 0.0 0.1 0.1 0.3 64.9 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.2 0.0 3.6 0.3 0.2 0.2 0.1 0.1 0.0 0.1 1.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1824.7 1801.2 1490.8 1923.8 1745.7 1736.7 1611.9 1644.5 1613.0 1564.5 1698.7 1770.4 196.3 6.4 5.5 81.9 0.5 2.2 50.8 0.3 2.2 5.2 2.3 1.3 26.5 4.3 3.2 38.6 52.1 0.1 0.4 0.0 9.8 1.1 14.5 23.2 2.4 121.3 3.6 2.7 1.4 0.2 0.0 18.4 0.0 39.3 1.3 5.9 150.6 1.6 0.0 3.3 5.3 0.0 0.0 2.2 3.7 32.4 32.9 1.9 5.4 14.0 0.0 125.0 0.0 2.0 0.6 0.3 0.0 11.7 1.3 7.3 0.2 4.5 2.3 50.2 6.6 6.6 10.4 0.7 0.4 0.4 2.7 0.0 1.0 0.5 0.0 2.2 FAM124B FLJ22746 ENSG00000124019 "Family with sequence similarity 124 member B" Q9H5Z6 2 224378698-224402107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 8.5" "Group enriched" "Detected in some" 4 "Adipocytes: 13.8;Endothelial cells: 10.8;Erythroid cells: 9.4;granulocytes: 4.5" "Cancer enriched" "Detected in many" 10 "testis cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 29.5;eosinophil: 17.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "HUVEC TERT2: 103.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA070240 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA070240: AB_2686238" "unprognostic (2.01e-1)" "unprognostic (1.83e-1)" "unprognostic (6.87e-3)" "unprognostic (2.49e-1)" "unprognostic (7.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.28e-2)" "unprognostic (5.78e-2)" "unprognostic (3.19e-1)" "unprognostic (1.85e-1)" "unprognostic (1.57e-1)" "unprognostic (3.36e-1)" "unprognostic (7.61e-3)" "unprognostic (1.36e-2)" "unprognostic (4.30e-1)" "unprognostic (2.25e-1)" "unprognostic (5.80e-3)" 5.2 0.5 1.4 1.1 1.2 4.7 4.3 1.4 1.7 1.5 0.9 0.9 1.0 1.6 0.3 1.4 1.2 1.2 1.8 1.3 1.6 0.6 1.9 2.3 0.7 1.8 1.7 0.4 0.4 2.4 0.2 8.5 1.5 0.5 1.0 0.2 0.8 0.5 1.2 1.8 1.0 2.3 1.6 0.5 0.6 0.3 1.7 1.1 1.0 4.6 0.7 1.5 1.4 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.5 0.1 0.0 0.0 0.0 15.0 0.0 0.1 0.0 0.0 0.0 103.4 0.0 4.8 0.2 0.0 0.1 0.0 0.1 6.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.7 7.5 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.5 3.0 17.2 0.2 2.3 0.0 0.0 0.7 0.0 7.9 0.0 0.0 0.0 0.1 5.4 0.8 0.0 2.5 1.1 1.4 1.2 1.4 1.7 1.3 1.6 1.8 1.7 1.5 1.6 1.7 1.1 13.8 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 1.2 0.3 0.2 10.8 0.0 9.4 0.2 0.0 0.1 0.4 0.0 0.8 4.5 0.0 2.2 0.4 0.4 0.0 0.2 0.0 0.0 0.9 0.6 0.0 0.0 0.7 0.0 1.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.3 0.0 0.1 0.1 0.0 0.1 1.1 0.1 0.0 0.0 FAM171A1 "APCN, C10orf38, FLJ12884" ENSG00000148468 "Family with sequence similarity 171 member A1" Q5VUB5 10 15211643-15371289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.7" "Cell type enhanced" "Detected in many" "Astrocytes: 263.8;Cholangiocytes: 98.7;Excitatory neurons: 166.9;Oligodendrocytes: 214.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 1.7;MAIT T-cell: 4.4;memory CD4 T-cell: 2.5;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.7;naive CD8 T-cell: 2.4" "Lineage enriched" "Detected in single" 19 "T-cells: 4.7" "Cell line enhanced" "Detected in many" "TIME: 105.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051345 Approved Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" Nucleoplasm "HPA051345: AB_2681449" "unprognostic (3.60e-2)" "unprognostic (7.15e-2)" "unprognostic (2.21e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (4.11e-2)" "unprognostic (9.84e-2)" "unprognostic (9.19e-2)" "unprognostic (2.28e-1)" "unprognostic (3.97e-2)" "unprognostic (3.09e-2)" "unprognostic (1.87e-1)" "prognostic favorable (2.71e-5)" "unprognostic (3.08e-1)" "unprognostic (1.86e-1)" "prognostic unfavorable (4.90e-6)" "unprognostic (3.28e-2)" 11.0 5.0 60.1 7.5 73.2 0.5 8.8 69.8 56.4 11.8 22.7 21.6 19.1 12.8 6.4 6.4 15.6 12.9 10.6 68.5 49.5 31.9 15.4 7.4 6.0 79.6 64.8 14.2 22.4 10.9 3.7 4.1 75.6 11.2 17.6 2.6 14.1 11.9 7.6 4.2 13.0 12.3 59.3 12.4 13.3 3.5 68.7 3.9 6.9 6.1 6.6 9.0 6.3 86.7 0.0 16.2 33.3 12.6 13.2 24.9 0.4 19.5 3.9 10.2 8.8 3.0 19.2 0.1 21.5 53.4 22.7 1.4 24.0 0.2 11.5 5.9 33.4 46.7 5.2 48.1 14.3 0.0 36.0 19.7 4.9 27.8 4.0 36.8 51.4 6.8 17.5 0.2 32.8 1.4 7.7 0.1 30.4 9.3 7.8 30.4 17.0 5.1 12.7 0.0 22.4 27.6 10.9 0.2 0.1 35.0 0.2 0.6 105.6 13.9 53.6 50.4 20.8 6.3 2.1 0.1 30.3 0.0 10.8 0.0 0.0 0.0 1.7 0.0 4.4 0.0 2.5 2.2 0.0 0.0 4.7 2.4 0.0 0.2 0.0 0.0 0.5 0.9 60.1 73.2 69.8 56.4 68.5 49.5 79.6 64.8 75.6 59.3 68.7 86.7 11.1 0.0 0.0 263.8 1.0 1.3 4.0 3.1 8.0 4.0 7.6 5.7 6.8 98.7 1.7 14.7 0.0 0.1 0.2 25.4 3.9 21.1 0.7 5.9 12.5 43.7 21.0 6.5 166.9 12.2 0.2 12.3 35.7 14.6 1.3 14.4 49.2 24.7 0.4 6.7 76.6 23.7 4.1 2.8 1.7 1.1 5.3 0.3 1.8 33.7 0.7 1.5 0.0 44.2 214.4 17.5 16.1 5.7 5.2 16.5 7.3 4.5 2.4 1.1 0.0 7.5 5.9 2.3 5.7 8.0 1.8 0.1 2.0 11.4 38.8 3.6 FAM228A "C2orf84, FLJ30851" ENSG00000186453 "Family with sequence similarity 228 member A" Q86W67 2 24175053-24200849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 35.1" "Group enriched" "Detected in some" 5 "Early spermatids: 119.7;Spermatocytes: 176.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 2.5;hTERT-RPE1: 1.1;TIME: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075817 Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA075817: " "unprognostic (2.57e-1)" "unprognostic (7.14e-2)" "unprognostic (2.92e-2)" "unprognostic (1.98e-3)" "unprognostic (7.13e-4)" "unprognostic (2.19e-3)" "unprognostic (1.55e-1)" "unprognostic (3.05e-1)" "unprognostic (9.57e-2)" "unprognostic (2.14e-1)" "unprognostic (4.44e-5)" "unprognostic (1.73e-2)" "unprognostic (1.04e-4)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" "unprognostic (2.30e-1)" "unprognostic (1.33e-2)" 2.0 0.9 1.9 0.6 1.7 0.0 1.6 1.4 2.8 0.9 0.0 0.9 0.3 0.7 0.9 0.9 0.6 1.1 1.7 1.3 1.0 0.8 0.3 0.8 0.6 0.8 0.7 0.7 0.3 0.1 0.4 1.0 0.8 0.8 0.3 0.9 0.2 0.9 0.4 0.4 0.4 0.5 0.2 0.4 0.7 35.1 0.7 0.3 0.6 0.4 0.2 0.9 0.5 1.9 0.1 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.0 0.2 0.2 0.0 0.1 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.1 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.1 1.9 1.7 1.4 2.8 1.3 1.0 0.8 0.7 0.8 0.2 0.7 1.9 0.4 3.2 0.5 3.3 0.0 0.5 0.1 0.0 0.0 0.4 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.7 119.7 0.0 0.4 0.5 0.0 0.0 5.5 0.5 0.2 1.6 0.0 0.0 0.0 0.6 1.1 0.1 0.5 1.7 5.8 0.0 0.0 0.8 0.4 24.8 2.8 0.3 0.0 2.8 0.1 0.3 1.0 3.0 3.1 0.7 0.0 4.5 0.0 0.1 0.0 0.0 0.1 0.2 6.6 1.0 0.8 176.0 10.4 0.0 0.1 0.1 0.1 0.5 0.0 0.2 FAM43A FLJ90022 ENSG00000185112 "Family with sequence similarity 43 member A" Q8N2R8 3 194685883-194689037 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.9" "Cell type enhanced" "Detected in many" "Adipocytes: 89.2;Endothelial cells: 102.4;Extravillous trophoblasts: 83.3;Hepatic stellate cells: 97.1;NK-cells: 75.2;Syncytiotrophoblasts: 162.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 123.7;NB-4: 72.8;PC-3: 56.9;TIME: 66.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048345 Uncertain Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA048345: AB_2680367" "unprognostic (1.61e-1)" "unprognostic (1.11e-1)" "unprognostic (9.18e-2)" "unprognostic (1.90e-2)" "unprognostic (5.71e-3)" "unprognostic (5.13e-3)" "unprognostic (9.80e-2)" "unprognostic (8.28e-2)" "unprognostic (4.96e-2)" "unprognostic (1.38e-1)" "unprognostic (3.92e-3)" "unprognostic (1.74e-1)" "unprognostic (2.14e-1)" "unprognostic (1.15e-1)" "unprognostic (1.45e-1)" "unprognostic (2.91e-3)" "prognostic unfavorable (9.96e-4)" 25.2 4.8 8.3 5.1 5.6 3.7 15.7 6.9 14.1 16.1 4.0 15.7 1.4 13.0 1.2 15.4 15.1 4.0 30.3 11.7 6.5 41.4 5.8 9.7 10.0 33.2 9.6 4.5 3.0 1.4 8.7 11.2 34.8 22.1 2.3 0.8 8.0 2.7 6.0 25.2 11.6 3.7 7.3 54.9 8.3 4.4 8.3 1.3 8.0 4.0 6.3 17.2 25.1 6.9 0.3 1.8 1.4 1.1 23.3 11.4 10.4 3.8 8.6 0.1 0.0 0.8 0.3 1.3 37.4 11.6 8.5 3.8 2.3 1.0 0.1 0.9 6.4 4.7 10.8 1.3 1.8 1.2 13.5 3.0 4.8 0.5 0.1 0.6 123.7 0.2 2.8 2.5 0.3 1.9 0.0 72.8 6.0 12.8 56.9 6.0 0.4 0.6 0.1 0.2 35.6 3.0 2.4 2.3 7.5 2.4 1.5 15.7 66.3 1.2 1.9 1.6 0.8 0.2 1.5 3.5 0.7 34.3 24.0 2.2 0.6 1.3 0.5 0.5 0.7 1.2 0.3 0.5 0.8 2.5 0.0 0.2 0.9 1.6 0.5 4.5 0.2 0.3 8.3 5.6 6.9 14.1 11.7 6.5 33.2 9.6 34.8 7.3 8.3 6.9 89.2 0.0 2.5 0.0 26.7 4.0 21.4 6.7 4.6 16.0 10.6 7.0 35.1 0.0 4.0 1.8 8.4 21.1 38.3 39.6 7.9 7.8 0.3 3.2 19.5 102.4 6.6 0.4 3.5 1.8 83.3 30.1 8.6 4.0 15.2 3.8 97.1 1.4 6.0 0.0 7.3 8.0 24.4 13.1 3.9 1.3 16.4 9.3 12.4 28.1 7.7 2.2 75.2 0.0 2.6 7.0 19.1 9.8 8.5 20.3 1.0 0.4 1.4 2.8 26.3 5.2 20.8 0.6 14.2 6.5 4.0 162.4 16.0 3.0 11.0 12.6 FAM89B "LRAP25, MTVR1" ENSG00000176973 "Family with sequence similarity 89 member B" Q8N5H3 11 65572349-65574198 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046895 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "HPA046895: AB_2679858" "unprognostic (1.16e-1)" "unprognostic (9.46e-3)" "unprognostic (1.02e-1)" "unprognostic (5.11e-2)" "unprognostic (4.09e-1)" "unprognostic (3.92e-3)" "prognostic unfavorable (2.98e-4)" "unprognostic (8.32e-2)" "unprognostic (1.51e-1)" "prognostic favorable (6.00e-4)" "unprognostic (1.69e-1)" "unprognostic (4.07e-3)" "prognostic unfavorable (9.48e-5)" "unprognostic (3.59e-2)" "unprognostic (2.63e-1)" "unprognostic (3.27e-2)" "unprognostic (1.12e-2)" 39.9 33.8 59.0 19.8 54.9 22.5 34.2 53.9 84.7 46.1 40.2 70.7 13.7 47.7 13.0 46.2 42.7 24.8 56.7 60.7 46.6 39.6 36.0 39.7 25.8 52.2 50.6 43.8 76.2 23.2 22.9 14.6 52.9 50.3 10.9 3.2 47.0 24.2 129.7 44.1 34.4 23.0 50.8 48.3 45.0 18.4 53.8 31.3 26.1 95.1 19.4 54.0 43.1 55.9 16.6 26.3 38.4 47.8 45.7 52.5 12.5 29.3 26.2 21.4 12.7 15.8 18.2 11.2 38.7 45.9 23.7 28.1 16.3 17.5 5.0 38.0 43.6 21.3 18.8 9.0 27.8 10.5 38.7 41.1 34.8 17.7 12.2 68.3 57.5 26.2 24.2 73.3 30.7 24.6 48.1 37.1 17.2 16.1 61.2 59.2 5.9 49.6 24.1 15.2 43.5 57.6 21.5 30.8 50.0 11.7 31.1 15.7 37.9 45.6 23.9 44.6 15.5 36.3 61.3 7.4 39.9 15.7 33.2 7.8 5.7 11.6 5.0 10.5 6.8 2.6 6.3 6.4 5.0 2.3 5.3 5.4 8.5 5.8 14.0 5.5 10.1 3.5 59.0 54.9 53.9 84.7 60.7 46.6 52.2 50.6 52.9 50.8 53.8 55.9 45.3 9.6 3.9 9.8 33.4 47.4 32.8 4.3 18.8 10.1 67.0 57.8 10.7 21.5 5.3 23.9 2.1 27.7 63.9 27.2 13.7 23.6 10.4 19.7 33.3 39.7 29.2 36.7 13.6 27.5 19.9 32.8 10.7 20.3 4.5 26.5 43.5 27.6 32.5 16.8 10.9 15.2 2.0 40.6 48.8 27.8 26.4 47.1 44.4 13.1 27.1 29.1 73.2 9.0 10.6 33.3 21.7 30.1 43.6 31.8 16.1 14.9 4.2 8.7 46.0 22.3 48.8 2.9 13.1 19.1 57.4 22.3 46.5 26.2 16.6 48.5 FAR2 "FLJ10462, MLSTD1, SDR10E2" ENSG00000064763 "Fatty acyl-CoA reductase 2" Q96K12 12 29149103-29340980 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.2;intestine: 34.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 114.3;Inhibitory neurons: 172.1;Microglial cells: 63.7;Syncytiotrophoblasts: 193.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 50.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 76.2;HUVEC TERT2: 84.0;NB-4: 74.2;SK-BR-3: 89.6;TIME: 68.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015884 Approved Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoli "HPA015884: AB_1853998" "unprognostic (6.32e-2)" "unprognostic (2.40e-2)" "unprognostic (1.50e-3)" "unprognostic (3.33e-3)" "unprognostic (2.41e-1)" "unprognostic (4.13e-3)" "unprognostic (4.30e-2)" "unprognostic (1.18e-1)" "unprognostic (3.11e-2)" "unprognostic (6.37e-2)" "unprognostic (5.70e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.33e-1)" "unprognostic (5.22e-3)" 8.3 9.0 4.1 9.3 8.3 17.1 9.3 1.2 8.5 4.3 0.0 34.5 17.6 5.6 36.2 7.4 3.6 5.2 6.6 6.2 9.2 5.0 3.8 11.3 7.9 1.2 2.9 2.3 3.2 1.3 2.4 18.1 1.3 2.6 28.2 9.4 4.4 1.9 6.3 9.0 19.2 7.6 1.4 12.2 4.9 9.2 5.2 7.0 4.4 2.6 3.0 6.5 3.7 4.9 2.5 4.9 4.9 1.2 6.8 26.9 2.1 21.3 24.7 5.8 5.4 8.2 28.0 3.7 5.4 3.4 4.3 1.5 13.4 0.2 1.4 1.8 32.2 76.2 10.7 2.7 14.7 30.0 24.0 7.5 0.2 8.7 11.0 14.3 84.0 2.9 6.6 2.7 0.9 0.8 19.9 74.2 19.3 1.6 54.5 16.1 7.9 3.1 25.7 7.2 8.6 7.9 4.8 89.6 37.8 9.7 4.1 28.2 68.2 15.6 4.6 5.6 9.3 4.4 4.9 1.8 24.5 38.5 13.7 3.8 22.8 50.0 5.0 13.9 3.4 2.0 8.3 6.2 8.1 1.8 2.9 3.2 41.0 4.0 8.0 3.1 16.1 9.6 4.1 8.3 1.2 8.5 6.2 9.2 1.2 2.9 1.3 1.4 5.2 4.9 9.1 0.0 3.3 7.8 0.6 1.3 0.1 0.2 0.6 2.0 1.4 0.8 12.1 0.0 1.4 0.0 0.0 16.0 1.1 35.7 0.0 0.1 31.5 0.4 2.9 11.9 7.2 4.6 114.3 0.2 19.6 4.8 5.6 0.4 10.8 0.0 9.7 0.0 19.3 5.0 172.1 21.8 0.0 22.2 3.7 6.4 1.2 12.2 16.0 63.7 6.9 0.5 1.0 24.6 6.9 3.3 36.8 0.4 8.0 0.4 15.1 0.4 3.2 1.2 0.0 4.2 3.6 16.6 1.0 0.3 0.3 193.9 4.2 0.9 23.7 0.3 FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Endothelial cells: 18.0;Fibroblasts: 17.9;Hepatic stellate cells: 33.2;Inhibitory neurons: 35.0;Microglial cells: 23.4;Oligodendrocytes: 54.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 11.2;fHDF/TERT166: 11.4;HSkMC: 13.6;HUVEC TERT2: 14.3;TIME: 21.9" "Low region specificity" "Detected in many" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" 3.3 1.0 3.2 1.4 4.1 0.0 2.7 1.2 2.7 4.0 0.7 6.4 0.9 3.0 1.3 2.3 1.9 4.3 4.0 3.8 2.0 2.8 2.5 4.5 0.8 3.1 2.8 4.9 0.9 3.0 0.6 2.9 2.8 3.7 2.3 0.5 1.0 2.6 1.6 1.4 2.2 3.5 3.5 2.7 2.0 0.7 3.3 1.1 4.0 4.8 0.8 2.5 1.8 4.8 0.0 0.9 7.4 0.8 15.5 11.2 0.0 2.6 3.0 1.2 1.2 0.0 0.4 0.0 3.1 11.4 1.5 0.0 2.8 3.2 0.7 0.0 1.3 1.7 3.3 0.1 5.4 1.1 0.0 13.6 1.9 0.7 7.0 9.1 14.3 0.0 0.0 1.9 6.7 0.1 0.5 0.0 0.5 0.0 0.3 0.9 1.5 0.0 0.1 0.0 0.2 1.5 0.4 0.0 0.0 0.4 0.0 0.0 21.9 7.8 2.2 2.7 1.1 0.3 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 4.1 1.2 2.7 3.8 2.0 3.1 2.8 2.8 3.5 3.3 4.8 19.3 6.4 0.0 8.8 0.0 1.7 0.2 1.5 0.0 3.7 0.3 1.3 6.9 0.0 0.3 5.5 0.0 0.1 0.9 0.0 0.0 0.7 0.9 0.6 8.8 18.0 0.0 0.0 9.4 0.2 0.0 17.9 1.1 1.0 0.0 1.2 33.2 7.4 0.2 0.0 35.0 0.0 0.0 2.2 2.2 0.2 5.9 0.3 3.6 23.4 0.0 1.1 1.0 6.0 54.4 0.3 0.0 4.9 1.4 0.4 0.0 0.7 0.1 0.2 0.0 5.3 4.1 0.1 0.6 0.5 0.6 0.0 0.3 5.7 0.0 0.1 FBLIM1 "CAL, FBLP-1, migfilin" ENSG00000162458 "Filamin binding LIM protein 1" Q8WUP2 1 15756607-15786594 "Predicted intracellular proteins" "Cell adhesion, Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.3;Paneth cells: 153.6;Peritubular cells: 191.5;Proximal enterocytes: 145.9;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 255.9;TIME: 420.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA025287, HPA072750" Approved Enhanced "Nucleoli fibrillar center,Cell Junctions,Focal adhesion sites" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions, Focal adhesion sites" "Nucleoli fibrillar center" "HPA025287: AB_1848443, HPA072750: AB_2686554" "unprognostic (4.10e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (2.26e-1)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.33e-2)" "unprognostic (8.77e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (2.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.33e-2)" "unprognostic (3.01e-1)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" 32.4 17.9 2.7 21.5 3.3 0.8 28.1 3.2 4.8 43.2 5.2 75.6 82.2 75.7 15.6 24.1 43.5 69.8 45.6 2.5 2.4 26.7 7.1 39.3 9.6 2.6 3.2 39.1 27.5 36.2 11.0 29.4 2.9 47.0 53.2 1.8 31.7 63.1 5.4 16.8 86.1 47.1 2.5 27.6 64.0 12.8 3.8 2.8 17.6 5.6 6.8 44.6 29.3 2.6 34.2 17.2 15.9 0.6 3.7 8.1 21.6 55.2 84.3 38.4 30.4 6.0 48.8 0.3 114.5 87.8 67.3 62.5 11.3 121.0 19.2 0.3 6.6 0.2 4.7 31.7 98.5 0.2 0.6 39.7 81.7 31.9 75.1 82.7 255.9 2.0 1.2 7.6 13.2 0.8 0.6 1.1 16.5 50.9 25.0 0.1 0.4 1.0 51.4 22.1 0.2 38.9 29.0 3.4 6.0 33.9 6.8 0.6 420.4 50.7 7.1 0.8 25.7 0.4 1.0 0.5 8.0 0.2 0.5 1.7 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.5 0.3 0.3 0.8 0.4 0.2 0.4 0.1 0.1 2.7 3.3 3.2 4.8 2.5 2.4 2.6 3.2 2.9 2.5 3.8 2.6 10.8 12.8 18.1 0.0 3.1 86.3 82.7 41.4 20.5 3.7 28.6 23.9 37.1 47.1 30.6 16.5 6.2 8.9 4.8 207.3 0.0 99.1 3.4 13.6 75.9 19.2 46.0 0.0 0.7 53.5 114.2 29.3 133.5 20.5 18.9 9.4 55.0 2.5 5.6 1.7 5.5 54.8 26.4 1.9 23.5 4.0 80.2 5.8 14.2 2.8 2.7 9.1 1.0 1.0 1.2 113.0 153.6 191.5 1.2 29.8 145.9 2.5 11.6 6.4 144.7 11.9 64.8 2.8 1.9 17.4 62.8 19.4 6.0 6.6 53.8 62.6 FGD5 "FLJ00274, FLJ39957, ZFYVE23" ENSG00000154783 "FYVE, RhoGEF and PH domain containing 5" Q6ZNL6 3 14810853-14934571 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 51.3;Endothelial cells: 44.7;Hepatic stellate cells: 55.6;Microglial cells: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 94.9;TIME: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014436, HPA014536, HPA019191" Uncertain Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA014436: , HPA014536: AB_1848518, HPA019191: AB_1848519" "unprognostic (2.57e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.28e-2)" "unprognostic (2.02e-2)" "unprognostic (1.03e-3)" "unprognostic (1.08e-1)" "unprognostic (4.10e-2)" "unprognostic (6.34e-2)" "unprognostic (5.53e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (3.46e-1)" "unprognostic (1.32e-2)" "prognostic favorable (7.50e-4)" 19.8 4.4 4.8 5.6 4.3 0.3 15.0 4.1 4.9 10.4 3.4 5.3 9.2 11.3 2.3 5.7 8.5 11.9 11.5 3.0 2.9 10.1 3.1 20.6 4.2 4.5 11.5 5.3 2.2 3.5 3.2 17.7 4.8 5.3 4.6 0.2 3.7 4.4 6.8 5.4 7.0 11.4 3.2 25.0 4.6 4.3 6.7 2.0 7.5 13.4 3.6 7.7 5.6 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 94.9 0.1 0.0 0.0 0.0 0.0 0.4 0.2 5.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.4 0.0 81.1 0.0 6.6 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 4.3 4.1 4.9 3.0 2.9 4.5 11.5 4.8 3.2 6.7 3.0 51.3 0.0 4.6 0.0 0.9 3.1 0.2 0.0 1.2 0.1 1.3 1.9 4.4 1.5 0.6 0.0 0.0 0.3 0.4 0.1 1.9 0.2 7.3 0.4 5.3 44.7 0.0 5.3 3.4 0.2 0.1 11.3 1.1 0.3 0.0 0.0 55.6 1.3 10.5 0.0 8.6 0.2 0.0 2.2 5.9 9.9 11.5 3.3 1.8 25.3 0.0 0.0 1.0 0.5 0.3 4.8 2.5 4.5 0.0 0.3 1.0 7.0 0.0 0.2 0.0 4.9 2.4 0.2 3.6 0.1 1.8 0.5 0.7 2.3 0.5 0.2 FGD6 "FLJ11183, ZFYVE24" ENSG00000180263 "FYVE, RhoGEF and PH domain containing 6" Q6ZV73 12 95076749-95217482 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 109.0;Microglial cells: 90.9;Pancreatic endocrine cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007974 Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA007974: AB_1848520" "unprognostic (1.28e-2)" "unprognostic (2.67e-3)" "unprognostic (6.06e-2)" "unprognostic (5.56e-2)" "unprognostic (1.65e-1)" "unprognostic (4.70e-2)" "unprognostic (4.66e-2)" "unprognostic (1.35e-3)" "unprognostic (1.32e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.62e-5)" "prognostic unfavorable (9.83e-4)" "prognostic unfavorable (5.46e-6)" "unprognostic (1.01e-2)" "unprognostic (1.38e-1)" "unprognostic (3.33e-2)" "unprognostic (1.92e-1)" 1.8 3.3 3.3 5.1 5.3 1.5 2.9 0.3 5.2 3.3 4.0 4.5 1.3 3.4 1.2 3.3 1.9 4.9 3.6 3.2 0.4 3.3 3.1 5.2 5.5 2.0 1.7 4.5 3.4 1.2 1.1 4.3 0.3 3.3 4.2 2.2 2.2 4.0 1.6 7.8 3.5 3.5 1.8 3.3 1.8 3.0 2.9 2.5 5.2 1.3 9.7 3.3 3.5 1.6 22.5 20.1 18.2 2.0 1.9 1.8 9.5 3.1 4.4 1.1 1.8 7.7 15.0 23.8 5.1 2.0 1.3 8.9 3.3 18.7 2.6 2.5 2.0 1.1 3.2 3.8 2.5 2.5 0.2 7.5 8.4 2.2 22.1 7.3 11.9 3.2 5.1 0.4 0.6 1.2 2.0 0.5 7.5 2.8 6.9 5.5 3.6 1.9 12.8 7.1 3.0 4.9 9.0 4.6 0.4 9.1 2.1 0.2 16.4 0.7 2.0 0.9 2.4 2.2 5.3 6.7 0.9 1.6 1.4 0.2 1.6 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.9 1.4 0.1 0.0 0.1 0.1 2.0 0.0 0.0 0.6 3.3 5.3 0.3 5.2 3.2 0.4 2.0 1.7 0.3 1.8 2.9 1.6 12.4 16.0 17.0 109.0 3.9 48.6 21.9 18.6 29.0 3.8 11.0 10.5 22.2 10.0 14.0 9.2 4.2 4.5 1.5 26.5 0.0 22.6 1.7 10.9 17.3 22.3 12.5 1.7 23.9 21.9 8.8 7.3 6.6 22.1 1.3 10.6 16.4 5.2 11.7 1.7 22.4 15.5 10.2 16.1 11.8 3.1 12.5 11.0 1.8 90.9 12.6 1.9 1.0 4.0 4.1 78.1 17.0 10.5 3.5 19.3 14.9 5.2 12.0 9.7 0.0 3.5 6.1 4.8 16.0 28.3 24.9 43.8 1.7 4.9 5.5 30.7 FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FKBP prolyl isomerase 1A" P62942 20 1368977-1393164 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Paneth cells: 977.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 675.2;granulocytes: 974.2;monocytes: 1013.4" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 1749.2;TIME: 1929.6" "CAB004639, HPA051798" Uncertain NA NA 12000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004639: AB_425434, HPA051798: AB_2681615" "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "unprognostic (5.22e-3)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "prognostic unfavorable (3.44e-7)" "unprognostic (7.05e-3)" "unprognostic (2.76e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-3)" "unprognostic (6.65e-2)" "prognostic unfavorable (6.69e-5)" "unprognostic (1.97e-2)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" 272.7 185.0 138.4 178.8 177.5 167.0 188.2 88.5 163.2 123.0 112.6 158.6 108.9 165.4 150.1 169.8 131.7 104.5 171.4 166.7 115.8 186.7 98.1 235.2 162.7 92.4 98.9 135.1 114.6 123.0 79.5 218.7 95.6 125.4 188.5 11.8 111.0 119.8 110.3 127.3 117.0 225.1 97.8 185.7 118.3 56.9 120.5 188.1 190.9 150.6 202.2 206.8 126.2 118.9 718.1 299.5 172.9 240.3 654.1 771.3 202.9 423.9 337.1 382.7 354.2 278.4 295.2 272.5 149.3 555.7 656.3 337.7 255.1 1007.2 419.7 68.8 170.5 284.2 113.9 473.3 406.4 390.5 168.0 484.7 332.0 410.3 412.6 513.3 1749.2 401.0 271.0 145.8 443.3 125.8 401.9 453.7 307.1 335.3 276.4 307.0 254.1 351.9 540.0 243.4 248.7 173.8 208.0 479.3 728.8 231.8 177.2 293.0 1929.6 1363.6 201.8 278.1 329.5 76.4 168.1 292.9 248.1 332.3 307.5 316.3 870.8 974.2 112.9 1005.8 104.3 128.1 135.5 133.2 675.2 136.2 140.1 132.6 805.0 160.6 1013.4 312.7 195.0 1153.8 138.4 177.5 88.5 163.2 166.7 115.8 92.4 98.9 95.6 97.8 120.5 118.9 779.1 86.6 77.2 0.0 160.6 263.1 211.2 393.3 152.0 17.6 175.6 156.5 59.7 170.1 179.5 172.9 0.0 281.8 148.3 456.2 238.7 432.4 47.7 98.7 183.8 814.8 330.6 196.4 0.0 337.5 702.0 212.2 160.0 122.5 143.5 95.3 623.6 113.5 746.7 35.3 0.0 245.9 329.6 541.8 436.5 52.2 200.0 428.8 241.9 0.0 527.4 52.2 152.4 0.0 0.0 483.6 977.5 162.9 214.8 221.1 210.8 332.1 123.0 11.7 138.1 87.4 224.7 169.3 141.8 329.4 299.3 231.5 150.1 347.3 318.0 245.7 FLNB "ABP-278, FH1, FLN1L, LRS1, TABP, TAP" ENSG00000136068 "Filamin B" O75369 3 58008400-58172251 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Myogenesis" "Actin-binding, Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 344.9;Pancreatic endocrine cells: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 523.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004747, HPA004886, CAB019322" Enhanced Supported "Golgi apparatus,Plasma membrane,Actin filaments,Cytosol" NA NA 20000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments, Cytosol" "CAB019322: , HPA004747: AB_1848599, HPA004886: AB_1848600" "unprognostic (1.29e-2)" "unprognostic (1.08e-2)" "unprognostic (5.97e-2)" "unprognostic (6.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (6.52e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (9.23e-2)" "prognostic favorable (3.45e-6)" "unprognostic (4.38e-2)" "unprognostic (1.36e-1)" "unprognostic (6.65e-3)" "unprognostic (2.33e-1)" 74.6 63.1 42.8 22.3 51.3 7.4 90.4 50.9 52.4 45.5 57.1 122.2 52.8 75.5 120.3 57.7 75.9 19.6 47.2 40.1 41.6 96.7 71.5 49.9 24.4 54.4 52.3 68.9 83.2 59.9 38.1 48.0 52.6 124.4 74.4 10.2 64.0 51.4 16.3 91.3 92.7 36.2 48.1 55.3 70.2 30.4 50.0 74.8 91.1 17.8 23.8 114.7 58.6 58.3 134.4 225.0 22.3 32.9 14.8 25.0 385.7 49.0 39.3 106.6 108.4 227.1 223.1 21.9 18.1 172.9 172.8 215.9 42.1 311.5 103.0 121.6 20.8 18.4 192.7 110.5 107.8 16.2 63.1 40.2 132.1 148.5 448.3 125.2 365.4 94.7 30.9 6.6 67.0 29.2 49.3 38.5 34.5 146.6 192.1 21.6 5.8 18.7 143.8 224.6 24.7 23.1 247.3 132.6 27.4 160.9 110.3 44.6 523.3 27.8 84.5 334.1 175.6 4.8 1.7 17.0 102.2 29.2 29.9 10.1 0.3 5.0 0.5 0.8 2.7 4.1 1.7 0.8 1.4 1.6 5.1 3.8 0.2 7.3 1.5 17.9 2.0 1.5 42.8 51.3 50.9 52.4 40.1 41.6 54.4 52.3 52.6 48.1 50.0 58.3 133.7 51.3 30.2 3.9 11.0 50.6 42.9 73.2 29.0 3.3 86.6 43.4 10.0 57.2 62.0 47.8 39.6 28.7 36.8 344.9 0.0 93.8 15.6 103.6 24.4 92.9 49.2 10.3 34.1 67.1 207.1 28.8 88.7 133.8 24.7 34.4 151.3 52.0 14.6 1.7 34.3 82.8 38.7 11.3 12.2 22.4 16.1 11.1 5.4 22.5 11.6 9.1 2.1 25.1 40.9 385.7 161.0 27.8 3.4 115.2 157.3 6.5 76.1 10.6 0.0 4.4 25.9 4.4 6.9 46.4 51.7 49.8 9.9 84.6 93.0 88.4 FLRT2 ENSG00000185070 "Fibronectin leucine rich transmembrane protein 2" O43155 14 85530144-85654428 "Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.6" "Cell type enhanced" "Detected in many" "Astrocytes: 279.5;Excitatory neurons: 549.6;Inhibitory neurons: 321.3;Leydig cells: 219.0;Microglial cells: 432.8;Oligodendrocyte precursor cells: 212.1" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in some" 6 "basal ganglia: 2.1;cerebral cortex: 8.2;hippocampal formation: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 60.1;HUVEC TERT2: 38.7;TIME: 55.3;U-138 MG: 58.8;U-2197: 43.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 17000 "Cluster 2: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (8.13e-3)" "unprognostic (4.59e-3)" "unprognostic (3.57e-2)" "unprognostic (1.46e-2)" "unprognostic (4.75e-2)" "unprognostic (9.46e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (5.34e-2)" "unprognostic (8.02e-6)" "unprognostic (1.98e-3)" "unprognostic (8.03e-2)" "unprognostic (1.50e-2)" "unprognostic (1.50e-5)" 9.2 4.5 0.8 4.5 2.1 0.1 2.9 0.0 8.2 11.0 2.3 2.7 0.9 6.1 3.0 3.5 6.4 9.1 3.8 4.7 0.0 1.4 1.2 2.3 3.5 0.0 0.0 29.6 21.7 1.3 1.9 1.2 0.0 5.1 3.1 3.1 1.9 3.3 7.3 6.1 1.7 5.2 0.0 3.0 2.2 4.6 0.2 1.2 4.9 3.1 2.6 5.3 4.2 0.0 0.0 0.2 8.9 0.0 7.9 14.5 0.0 9.7 6.3 9.0 8.4 0.0 0.0 0.0 0.0 28.5 0.9 2.0 13.6 18.6 21.8 0.0 7.8 0.0 5.3 0.0 25.2 2.1 0.0 8.0 10.6 7.5 60.1 2.7 38.7 0.0 0.0 0.0 21.8 0.0 0.0 0.0 4.2 0.0 0.2 0.0 10.8 0.0 0.0 0.0 2.1 0.0 2.3 0.0 3.2 11.8 0.0 0.1 55.3 58.8 9.9 43.0 17.8 0.0 0.0 0.0 18.5 0.0 5.8 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 2.1 0.0 8.2 4.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.9 0.0 1.3 279.5 0.1 21.4 1.7 5.2 6.2 7.0 3.9 4.4 4.0 10.0 0.4 1.8 0.0 0.4 0.1 0.1 0.0 66.2 3.1 2.2 65.1 15.9 0.0 0.0 549.6 42.8 0.2 34.3 0.5 1.6 0.0 39.9 66.0 0.2 2.4 10.1 321.3 0.0 0.0 1.3 6.6 7.7 219.0 1.2 1.8 432.8 0.6 13.2 0.0 212.1 9.0 20.4 0.0 124.8 0.0 1.1 0.0 0.2 1.7 1.4 13.1 3.2 8.5 1.1 0.6 1.0 24.0 0.8 0.8 32.3 0.0 0.2 FMNL3 "DKFZp762B245, MGC45819, WBP3" ENSG00000161791 "Formin like 3" Q8IVF7 12 49636499-49708165 "Predicted intracellular proteins" Angiogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 35.8;Cone photoreceptor cells: 39.6;dendritic cells: 48.6;Microglial cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002552, HPA023201" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles, Plasma membrane" Cytosol "HPA002552: AB_1078862, HPA023201: AB_1848575" "unprognostic (2.97e-1)" "unprognostic (2.77e-3)" "unprognostic (4.97e-3)" "unprognostic (7.19e-2)" "unprognostic (5.42e-2)" "unprognostic (2.33e-3)" "unprognostic (5.37e-3)" "unprognostic (1.52e-2)" "unprognostic (2.83e-1)" "unprognostic (1.54e-1)" "unprognostic (6.67e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (1.04e-1)" "unprognostic (2.31e-1)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" 12.2 5.7 13.7 20.5 13.2 5.2 10.6 13.0 11.2 9.6 3.0 8.0 5.7 11.2 19.2 4.5 6.9 11.1 12.6 11.0 12.6 9.3 2.7 17.4 23.5 21.7 14.6 16.1 3.2 3.6 4.1 14.0 18.2 6.0 5.6 2.7 4.6 4.4 5.6 4.4 10.2 11.5 17.7 13.4 6.6 10.1 20.4 20.1 13.4 6.7 28.3 8.6 6.3 20.4 8.6 2.5 18.4 6.1 5.0 20.1 0.2 10.4 21.0 13.8 12.1 9.7 2.3 18.2 19.5 12.4 15.2 0.4 9.5 4.3 12.6 16.2 3.6 20.1 2.9 0.5 8.8 4.0 25.1 12.7 0.7 21.7 9.1 41.2 37.1 9.0 4.6 13.0 20.5 6.3 16.6 6.0 6.0 0.9 5.5 7.9 23.0 2.8 13.1 1.3 3.0 8.6 6.0 0.8 11.8 9.3 1.5 5.9 47.2 34.2 11.8 0.6 18.2 6.7 0.4 9.8 21.3 12.4 14.7 3.0 0.1 0.8 0.8 0.4 0.4 0.2 0.3 0.5 0.2 1.1 0.4 0.5 0.0 0.6 0.3 5.1 0.1 0.5 13.7 13.2 13.0 11.2 11.0 12.6 21.7 14.6 18.2 17.7 20.4 20.4 35.8 3.2 3.4 6.8 17.5 1.7 0.7 0.4 2.2 11.3 1.3 2.3 3.3 0.0 1.4 1.8 39.6 2.1 48.6 0.1 0.0 0.3 2.0 0.7 2.6 29.7 0.0 1.7 16.0 0.6 0.8 7.1 1.5 2.0 27.8 5.4 15.7 0.8 11.1 3.3 6.5 0.8 0.0 6.9 9.0 4.6 3.7 17.7 5.4 119.0 22.9 0.5 16.5 27.6 5.5 0.8 0.1 6.4 1.8 0.8 0.0 0.2 0.2 2.0 13.1 15.5 10.3 5.9 7.5 0.4 1.4 2.5 13.6 2.6 0.1 0.4 FOCAD "FLJ20375, KIAA1797" ENSG00000188352 Focadhesin Q5VW36 9 20658309-20995955 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "choroid plexus: 154.6" "Cell type enhanced" "Detected in all" "Excitatory neurons: 529.1;Inhibitory neurons: 314.2;Oligodendrocyte precursor cells: 140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055015 Approved Uncertain Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA055015: AB_2682673" "unprognostic (3.05e-2)" "unprognostic (1.02e-1)" "prognostic favorable (3.25e-4)" "unprognostic (3.69e-3)" "unprognostic (4.14e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (9.64e-2)" "unprognostic (7.38e-2)" "unprognostic (1.23e-1)" "unprognostic (5.26e-2)" "unprognostic (9.15e-2)" "prognostic favorable (3.09e-8)" "unprognostic (1.90e-1)" "unprognostic (2.33e-1)" "unprognostic (3.99e-2)" "unprognostic (1.41e-2)" 7.3 19.4 15.0 6.1 14.7 5.2 7.7 12.7 21.9 8.5 154.6 9.5 4.5 9.0 11.2 8.9 13.2 5.2 12.5 23.0 20.6 9.5 4.9 8.6 5.3 10.7 8.1 7.4 12.8 12.3 25.1 8.3 10.5 10.5 10.4 7.1 11.9 7.1 11.2 8.5 6.4 9.0 5.2 6.2 8.2 7.7 15.8 14.5 20.4 11.8 6.2 7.3 7.7 17.5 32.8 22.2 23.7 17.8 21.7 24.7 12.5 19.1 30.2 13.3 15.1 14.8 11.0 13.4 9.9 27.4 11.1 11.2 20.8 37.8 23.0 59.8 15.4 10.5 25.3 18.5 11.2 17.5 13.0 22.9 25.5 13.2 21.6 18.5 51.3 11.1 0.3 19.2 22.3 12.6 13.3 33.0 18.7 17.4 22.2 0.1 10.7 9.0 20.6 13.9 15.7 7.9 12.6 21.3 5.2 31.5 13.3 10.2 31.7 0.1 8.7 14.7 17.5 4.7 28.3 15.0 0.0 24.3 8.0 6.8 1.6 4.9 2.9 3.3 3.8 1.5 2.5 2.8 4.0 2.6 2.2 2.7 1.2 2.7 1.9 1.6 2.6 1.7 15.0 14.7 12.7 21.9 23.0 20.6 10.7 8.1 10.5 5.2 15.8 17.5 7.0 9.6 14.7 85.8 5.2 2.9 2.8 4.5 6.8 5.8 5.8 5.1 14.9 4.3 8.6 16.5 4.2 4.7 4.1 7.9 1.9 8.1 16.6 21.2 6.7 6.0 17.5 5.5 529.1 8.6 7.6 8.7 12.8 6.8 5.1 13.9 9.7 4.0 5.1 11.8 314.2 10.1 10.2 4.4 3.5 5.0 5.0 5.3 8.8 74.9 2.8 7.9 2.1 140.8 59.0 8.9 3.4 3.8 10.7 5.8 2.5 4.8 25.0 4.0 6.6 11.2 6.7 13.7 7.5 11.2 3.7 3.3 5.7 7.0 10.4 3.0 FOXC2 "FKHL14, MFH-1" ENSG00000176692 "Forkhead box C2" Q99958 16 86566829-86569728 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 5.6" "Group enriched" "Detected in some" 4 "Peritubular cells: 30.9;Sertoli cells: 19.7;Smooth muscle cells: 33.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 25.2;HUVEC TERT2: 19.5;LHCN-M2: 31.2;TIME: 36.0;U-138 MG: 18.4;U-2197: 31.5;U-87 MG: 24.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 6 "spinal cord: 42.7" HPA056302 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Nuclear bodies" "HPA056302: AB_2683093" "unprognostic (3.17e-2)" "unprognostic (1.76e-3)" "unprognostic (4.87e-2)" "unprognostic (4.32e-1)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (4.49e-2)" "unprognostic (1.15e-2)" "unprognostic (4.71e-2)" "unprognostic (8.88e-2)" "unprognostic (1.47e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.57e-7)" "unprognostic (1.12e-2)" "unprognostic (3.47e-2)" "unprognostic (2.43e-1)" "unprognostic (1.84e-4)" 2.4 1.5 0.5 0.3 1.1 0.0 1.8 0.9 1.6 2.2 3.2 0.5 0.1 0.8 0.6 0.5 2.0 1.3 5.6 0.4 0.4 5.4 0.1 2.1 0.4 0.5 0.5 1.1 0.2 0.1 2.4 0.1 0.5 1.0 0.1 0.1 2.4 0.6 0.7 0.8 0.4 0.4 0.7 0.0 0.4 1.9 0.7 0.1 2.0 0.5 0.1 0.8 1.5 0.3 0.0 0.0 0.0 0.0 5.8 7.8 0.0 11.3 14.3 8.0 1.5 0.0 0.0 0.0 1.5 1.4 11.2 0.0 0.2 3.3 7.0 0.0 0.6 0.0 7.9 0.0 2.7 0.0 0.0 1.3 3.4 25.2 7.9 14.5 19.5 0.0 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.5 0.1 0.0 1.7 0.0 0.1 0.1 0.0 0.0 1.8 0.0 0.0 5.9 0.0 0.0 36.0 18.4 0.0 31.5 0.0 0.0 0.0 0.0 24.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.9 1.6 0.4 0.4 0.5 0.5 0.5 0.7 0.7 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.8 2.1 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.5 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.6 1.5 0.1 1.8 1.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 30.9 1.2 0.8 0.0 0.0 0.0 0.1 19.7 0.6 33.2 0.2 5.0 0.5 0.0 0.0 0.0 0.0 0.1 1.4 FOXP1 "12CC4, hFKH1B, HSPC215, QRF1" ENSG00000114861 "Forkhead box P1" Q9H334 3 70954708-71583989 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 41.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTEC/SVTERT24-B: 95.0" "Low region specificity" "Detected in all" "HPA003876, CAB011501" Supported Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB011501: AB_732428, HPA003876: AB_1078907" "unprognostic (2.31e-1)" "unprognostic (4.35e-3)" "unprognostic (2.09e-2)" "unprognostic (3.54e-2)" "unprognostic (2.69e-1)" "unprognostic (2.81e-3)" "unprognostic (1.68e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (2.03e-1)" "unprognostic (4.38e-3)" "unprognostic (3.40e-1)" "unprognostic (6.14e-2)" "unprognostic (1.05e-1)" "unprognostic (8.65e-2)" "unprognostic (1.27e-1)" "unprognostic (6.05e-2)" 16.5 3.8 5.0 20.3 41.1 38.5 14.5 0.3 12.5 11.2 9.9 28.7 12.2 15.3 6.5 23.0 14.3 21.0 12.7 7.8 0.0 7.0 13.0 22.9 22.2 3.1 6.7 32.4 16.8 6.5 9.1 13.7 0.9 21.2 23.4 2.6 29.7 9.6 8.2 10.9 15.3 22.7 0.1 17.8 20.6 14.4 6.6 26.3 14.5 11.1 25.4 21.6 14.2 8.1 9.6 8.0 16.8 13.2 8.4 21.3 8.2 26.3 30.9 22.0 17.4 51.9 11.2 31.1 4.3 12.9 17.6 6.9 31.0 22.8 40.3 7.8 11.7 13.0 17.0 52.7 20.5 25.7 31.6 21.7 10.3 95.0 42.1 18.3 36.6 15.4 13.6 36.7 10.8 42.6 11.9 9.3 19.7 7.2 39.9 38.0 30.7 4.7 18.8 30.1 14.5 27.6 32.6 7.7 1.9 15.9 5.6 21.9 47.7 34.9 14.3 48.9 42.2 9.0 7.1 41.8 22.5 35.7 7.5 46.9 15.3 15.2 18.3 13.1 19.4 58.1 38.7 22.6 13.0 62.2 60.8 40.0 27.0 22.2 25.3 21.7 35.9 28.8 5.0 41.1 0.3 12.5 7.8 0.0 3.1 6.7 0.9 0.1 6.6 8.1 158.8 73.7 121.3 130.9 266.5 183.0 170.6 58.2 176.4 30.3 98.5 115.1 42.1 148.7 72.0 33.1 18.8 47.2 122.9 118.1 31.3 79.0 156.0 116.3 48.2 184.9 271.6 111.5 391.0 95.1 12.6 90.4 95.8 128.0 219.8 117.7 184.9 72.3 49.5 6.7 139.9 231.2 154.6 117.6 209.0 89.6 42.0 101.3 37.4 414.1 120.3 15.5 116.4 184.5 286.4 124.8 102.8 24.8 66.0 178.8 91.7 19.4 83.7 42.8 92.1 102.9 119.4 13.7 33.6 111.5 101.4 52.4 168.1 33.1 157.2 146.3 FRMD4B "GRSP1, KIAA1013" ENSG00000114541 "FERM domain containing 4B" Q9Y2L6 3 69168782-69542583 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 84.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1209.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 39.8;hTERT-HME1: 52.7;HUVEC TERT2: 55.1;TIME: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009705 Uncertain Supported Approved "Nucleoplasm,Golgi apparatus,Centriolar satellite" NA NA 17000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Centriolar satellite" "Nucleoplasm, Golgi apparatus" "HPA009705: AB_1849147" "unprognostic (1.36e-1)" "unprognostic (2.92e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (4.59e-2)" "unprognostic (9.73e-2)" "unprognostic (1.49e-1)" "unprognostic (2.02e-1)" "unprognostic (2.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.09e-2)" "unprognostic (8.23e-2)" "prognostic favorable (5.01e-4)" "unprognostic (1.49e-1)" "unprognostic (7.54e-2)" "unprognostic (2.79e-1)" "unprognostic (4.39e-3)" 11.0 4.8 17.5 12.3 46.7 15.5 16.1 26.9 30.9 24.9 7.0 12.8 9.1 11.3 9.3 26.8 13.2 19.2 17.4 20.8 29.3 16.3 34.5 24.8 10.9 39.4 37.1 10.9 8.2 3.7 4.0 25.5 36.3 16.9 12.9 21.9 37.1 10.5 2.3 23.0 12.5 10.5 22.7 32.3 15.0 4.7 42.0 14.1 27.1 4.6 11.2 13.7 15.8 84.0 6.7 1.8 10.4 0.3 0.2 1.5 11.3 0.5 1.7 0.8 0.5 39.8 11.3 0.8 3.5 0.5 1.0 25.9 4.9 35.3 1.2 2.2 3.3 20.4 2.6 2.3 0.7 5.2 10.2 1.7 35.2 1.0 52.7 1.6 55.1 4.7 1.6 5.8 3.0 7.7 0.5 0.8 5.6 8.9 8.5 32.2 2.8 1.0 14.8 4.6 12.1 15.6 1.7 12.2 35.5 9.3 4.6 6.8 47.1 0.6 4.3 0.4 1.8 0.6 0.3 1.2 0.4 13.5 13.5 18.3 27.6 2.3 1.9 13.8 7.0 1.6 6.3 2.8 16.9 2.0 1.9 1.8 7.1 3.8 2.3 16.8 15.4 7.7 17.5 46.7 26.9 30.9 20.8 29.3 39.4 37.1 36.3 22.7 42.0 84.0 20.6 41.7 83.6 2.9 3.6 60.7 33.4 57.8 69.4 13.8 34.4 21.7 33.4 41.5 58.5 14.7 218.9 49.9 20.3 74.4 33.2 32.6 18.9 207.9 49.3 64.3 24.5 8.6 4.2 17.3 19.7 32.1 75.4 282.6 34.7 97.5 89.3 53.6 92.6 0.0 92.7 42.1 36.7 138.7 112.7 4.0 6.5 105.2 28.4 93.7 26.3 13.5 1.0 129.2 1209.1 24.5 67.0 18.4 6.9 61.1 10.7 55.6 38.2 109.2 6.6 11.8 21.0 0.0 3.5 79.9 51.4 58.3 44.6 32.1 32.2 172.8 FUT8 ENSG00000033170 "Fucosyltransferase 8" Q9BYC5 14 65410592-65744121 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.3" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1019.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 15.6;NK-cells: 14.8;T-cells: 10.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017129, HPA043410" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB017129: , HPA043410: AB_2678467" "unprognostic (1.67e-1)" "unprognostic (1.63e-1)" "unprognostic (3.28e-2)" "unprognostic (1.65e-3)" "unprognostic (2.10e-1)" "unprognostic (5.61e-2)" "unprognostic (1.41e-1)" "unprognostic (8.81e-2)" "unprognostic (2.00e-2)" "unprognostic (1.33e-3)" "unprognostic (8.09e-2)" "unprognostic (1.94e-1)" "unprognostic (1.04e-3)" "unprognostic (1.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" 7.9 8.2 21.0 11.9 38.2 3.6 10.5 44.1 28.2 6.9 0.0 11.4 17.5 9.0 5.3 6.8 15.6 11.1 4.7 20.4 27.7 6.9 3.4 8.1 11.7 32.8 29.9 7.3 9.9 9.6 4.6 17.3 29.3 5.8 11.6 8.3 42.6 10.5 2.5 5.3 17.4 11.0 29.4 10.2 31.8 16.4 29.7 11.3 8.4 6.3 18.6 13.3 4.5 64.3 115.9 22.5 12.6 110.6 49.5 38.4 61.6 35.9 64.8 30.3 32.6 16.9 44.8 30.7 29.2 40.1 79.4 9.0 29.9 11.4 45.6 124.2 11.0 33.5 7.2 23.0 26.8 7.6 23.9 96.0 6.8 39.3 19.4 124.4 69.6 17.1 14.1 28.8 20.8 60.8 36.6 16.7 14.7 59.6 66.6 26.9 10.3 17.2 46.5 33.1 23.4 16.6 20.8 9.8 8.0 70.6 10.2 12.9 141.8 34.5 36.0 15.3 30.5 47.3 18.5 74.3 68.6 13.6 11.1 0.7 2.0 0.7 3.6 0.9 3.8 15.6 6.2 5.6 2.6 8.3 6.6 6.6 0.3 14.8 1.4 2.6 10.0 2.9 21.0 38.2 44.1 28.2 20.4 27.7 32.8 29.9 29.3 29.4 29.7 64.3 19.0 12.8 32.5 227.5 43.1 12.1 7.4 11.5 17.1 10.1 18.3 11.7 5.9 8.6 18.9 12.9 4.2 45.5 8.3 5.9 0.0 9.1 37.9 9.9 14.6 16.0 5.4 15.8 169.0 31.7 28.1 22.7 78.0 10.2 7.6 3.3 14.6 3.5 13.0 8.4 166.4 26.5 2.0 12.2 8.6 15.3 12.8 10.2 1.8 70.3 3.6 27.8 9.2 138.7 1019.1 54.7 10.3 13.5 124.3 8.8 24.5 8.4 15.3 9.1 0.0 14.3 13.2 34.6 26.8 7.4 9.8 14.1 18.9 10.6 21.7 7.2 FZD4 "CD344, EVR1" ENSG00000174804 "Frizzled class receptor 4" Q9ULV1 11 86945679-86955395 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 120.1" "Cell type enhanced" "Detected in many" "Adipocytes: 83.0;Collecting duct cells: 36.8;Endothelial cells: 51.2;Hepatic stellate cells: 99.6;Sertoli cells: 32.9" "Cancer enhanced" "Detected in all" "renal cancer: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 63.6;Hep G2: 85.2;HSkMC: 46.0;HUVEC TERT2: 93.6;TIME: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042328, HPA074833" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA042328: AB_10962494, HPA074833: AB_2686716" "unprognostic (6.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.87e-2)" "unprognostic (5.51e-2)" "unprognostic (1.82e-1)" "unprognostic (6.97e-2)" "unprognostic (3.33e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (2.22e-1)" "prognostic favorable (8.60e-5)" "unprognostic (1.05e-2)" "unprognostic (9.96e-2)" "unprognostic (9.22e-2)" "unprognostic (1.97e-1)" 120.1 9.5 6.7 5.8 6.2 0.3 55.6 5.1 7.3 12.5 7.8 14.9 2.8 12.2 7.6 6.5 16.3 11.5 27.4 5.6 5.9 27.1 14.6 32.9 6.2 6.5 6.3 12.9 9.5 6.4 8.7 11.7 7.0 12.5 6.3 1.1 12.2 30.2 31.5 5.9 8.8 13.4 5.6 14.1 14.1 5.1 8.5 3.9 18.1 40.6 4.6 10.5 9.5 5.9 1.3 1.1 2.7 5.2 63.6 16.5 3.7 8.4 7.6 3.2 3.3 7.1 0.9 0.0 1.8 2.6 4.4 2.8 3.1 1.3 2.5 0.2 2.1 2.8 2.3 85.2 18.9 0.0 0.1 46.0 0.5 2.8 0.5 7.5 93.6 0.1 3.9 0.4 2.2 2.2 0.0 0.0 3.9 7.5 18.8 0.1 4.8 0.2 9.0 13.7 0.6 0.8 3.5 1.0 1.4 5.6 12.0 0.0 46.3 7.8 5.1 9.2 1.7 0.4 1.3 0.0 1.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 6.2 5.1 7.3 5.6 5.9 6.5 6.3 7.0 5.6 8.5 5.9 83.0 0.0 1.3 9.8 0.5 1.5 0.5 1.3 2.2 0.7 5.5 3.2 8.3 7.2 2.0 36.8 10.4 0.2 0.5 1.0 3.9 0.5 0.7 0.4 2.7 51.2 0.0 2.7 8.1 1.6 0.2 17.7 4.1 0.5 0.0 9.1 99.6 14.1 0.2 0.0 3.4 1.3 0.0 6.7 1.8 2.2 9.3 0.6 0.0 10.3 0.0 0.2 2.1 3.0 0.7 1.0 0.1 6.8 0.3 1.4 0.7 9.4 2.1 0.2 32.9 14.4 26.6 0.3 3.2 1.3 0.6 0.3 0.4 16.6 1.1 0.2 GABBR2 "GABABR2, GPR51, GPRC3B, HG20" ENSG00000136928 "Gamma-aminobutyric acid type B receptor subunit 2" O75899 9 98288109-98708935 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 90.4" "Group enriched" "Detected in some" 4 "Excitatory neurons: 386.5;Inhibitory neurons: 395.1" "Group enriched" "Detected in many" 10 "glioma: 7.2;thyroid cancer: 11.6;urothelial cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 14.6;fHDF/TERT166: 7.3;HUVEC TERT2: 29.5;U-138 MG: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013820, HPA031684, CAB079065" Enhanced Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB079065: , HPA013820: AB_1849364, HPA031684: AB_2673993" "unprognostic (2.00e-1)" "unprognostic (7.56e-2)" "unprognostic (3.75e-1)" "unprognostic (3.09e-5)" "unprognostic (2.52e-1)" "unprognostic (1.16e-1)" "unprognostic (2.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.66e-1)" "unprognostic (4.43e-2)" "unprognostic (1.43e-2)" "unprognostic (2.06e-1)" "unprognostic (1.76e-2)" "unprognostic (3.52e-2)" "unprognostic (1.91e-1)" "unprognostic (2.68e-2)" "unprognostic (3.45e-2)" 0.0 3.6 26.0 0.2 40.8 0.0 0.0 10.6 90.4 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.6 39.9 18.0 0.0 0.0 0.3 0.0 12.7 19.6 0.0 0.1 0.2 0.6 0.1 12.5 0.0 0.0 8.5 0.0 0.1 2.8 0.2 0.0 0.1 8.3 0.0 0.2 0.6 39.5 0.0 1.4 0.5 0.2 0.5 0.0 36.3 0.0 0.0 0.0 0.0 0.1 0.1 1.2 14.6 2.9 3.0 5.5 0.1 0.1 0.0 0.9 7.3 0.6 0.0 0.1 0.2 1.0 0.0 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.9 0.2 0.0 29.5 0.0 0.3 0.1 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 4.0 0.0 0.1 3.5 0.0 0.0 0.0 0.1 1.2 11.5 0.7 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 26.0 40.8 10.6 90.4 39.9 18.0 12.7 19.6 12.5 8.3 39.5 36.3 0.1 0.0 0.0 14.0 0.0 0.1 0.0 0.0 0.0 86.4 0.5 0.1 1.9 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 90.3 0.1 0.0 0.6 0.0 0.0 386.5 0.2 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 395.1 0.0 0.0 0.0 0.0 34.5 0.3 0.1 1.8 11.2 0.0 1.8 0.0 26.2 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.4 0.0 0.3 1.3 0.7 0.9 0.0 0.1 0.4 0.0 0.3 0.1 0.0 GALNT1 GalNAc-T1 ENSG00000141429 "Polypeptide N-acetylgalactosaminyltransferase 1" Q10472 18 35581117-35711834 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 331.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012628 Uncertain "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA012628: AB_1849439" "unprognostic (9.81e-2)" "unprognostic (1.01e-1)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" "unprognostic (2.08e-1)" "unprognostic (2.83e-2)" "unprognostic (1.96e-2)" "unprognostic (7.06e-2)" "unprognostic (2.03e-2)" "unprognostic (1.51e-2)" "unprognostic (3.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (4.38e-2)" "unprognostic (2.74e-2)" "unprognostic (1.07e-2)" "unprognostic (8.60e-2)" 28.9 20.6 11.9 27.4 12.1 26.0 37.2 12.3 14.2 26.5 15.1 42.8 42.9 19.4 19.7 57.6 15.9 28.9 23.8 10.9 14.4 17.4 45.9 23.3 33.5 13.1 13.2 16.9 24.6 12.2 13.5 52.0 13.5 25.4 41.1 17.1 46.8 18.0 29.0 52.4 49.3 22.7 13.1 25.4 27.1 16.9 13.1 18.6 30.0 37.3 40.8 70.5 27.0 13.9 32.5 34.9 40.5 37.6 78.5 74.0 53.4 33.2 35.4 30.3 27.4 21.0 61.9 38.3 34.9 36.0 28.7 24.4 20.2 63.8 48.1 45.0 18.5 48.7 62.8 48.8 39.2 106.6 62.1 50.7 59.7 47.6 52.1 90.1 331.4 30.8 14.8 49.3 118.9 26.1 31.6 40.5 41.6 33.5 16.4 38.9 53.0 18.5 124.8 148.9 21.8 42.9 59.4 43.0 36.2 77.1 32.9 82.8 116.3 55.7 22.5 37.0 37.1 70.1 35.7 72.5 39.1 72.1 29.5 7.2 3.4 7.6 3.2 4.5 3.6 4.1 2.2 2.9 4.0 2.4 2.0 3.0 4.3 4.6 6.6 4.4 2.5 1.4 11.9 12.1 12.3 14.2 10.9 14.4 13.1 13.2 13.5 13.1 13.1 13.9 85.6 80.1 44.1 35.9 33.4 29.8 28.4 28.8 22.2 31.3 77.2 43.8 43.3 48.6 39.9 16.5 12.5 31.0 44.8 109.1 7.9 42.6 1.4 77.6 44.7 41.7 38.9 30.9 57.5 39.9 92.7 49.8 26.0 73.0 20.3 51.7 35.7 71.3 77.9 85.8 56.3 59.0 16.2 58.8 37.1 2.9 19.0 56.7 19.6 57.1 41.3 105.9 28.8 54.3 56.8 58.5 51.4 18.0 36.7 54.4 76.8 22.0 33.5 28.5 13.1 55.2 28.7 6.5 12.2 26.3 82.1 33.2 33.7 50.3 85.3 52.8 GALNT7 GALNAC-T7 ENSG00000109586 "Polypeptide N-acetylgalactosaminyltransferase 7" Q86SF2 4 173168811-173323967 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 143.4;Inhibitory neurons: 172.0;Intestinal goblet cells: 126.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064243, HPA065317" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 6200000 "Cluster 5: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" Nucleoplasm "HPA064243: AB_2685223, HPA065317: AB_2685465" "unprognostic (1.81e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.53e-4)" "unprognostic (1.37e-3)" "unprognostic (1.48e-1)" "unprognostic (6.86e-3)" "unprognostic (2.72e-2)" "unprognostic (1.77e-1)" "unprognostic (2.85e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (7.65e-4)" "unprognostic (1.33e-1)" "unprognostic (4.66e-3)" "unprognostic (3.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.34e-3)" "unprognostic (5.97e-2)" 6.4 6.4 6.4 16.3 8.8 11.5 23.3 34.2 8.3 25.1 3.5 47.8 29.1 16.9 7.0 14.9 9.8 15.6 5.9 6.6 7.8 7.8 2.9 9.6 12.2 12.6 8.3 11.2 22.2 8.7 5.2 13.0 11.7 39.7 52.8 22.4 27.4 8.1 1.4 3.9 33.7 16.7 10.1 11.0 65.7 11.9 8.4 60.0 13.5 3.9 9.8 17.0 5.9 16.0 71.1 37.2 35.0 11.2 18.6 27.1 50.3 18.1 20.5 16.7 23.0 11.5 109.9 39.4 13.3 16.6 45.2 59.2 15.0 32.0 22.7 154.3 29.1 47.8 72.2 0.4 12.2 71.6 32.8 17.5 28.3 37.6 18.9 63.4 112.3 28.2 32.6 59.3 86.0 23.5 52.7 39.4 34.8 70.2 24.0 52.1 32.4 10.2 123.2 32.8 28.2 21.5 8.5 50.4 25.4 45.3 20.2 21.0 135.6 11.9 52.3 0.6 40.0 17.2 0.2 20.8 48.6 42.3 43.6 13.2 14.3 18.9 5.1 7.5 7.2 6.2 5.7 5.3 12.4 3.3 4.4 3.3 21.3 7.5 8.0 5.0 9.2 6.4 6.4 8.8 34.2 8.3 6.6 7.8 12.6 8.3 11.7 10.1 8.4 16.0 10.0 6.4 38.0 72.8 12.1 1.8 9.0 12.3 4.0 47.9 41.1 19.8 9.6 8.6 36.0 20.2 2.1 1.4 16.4 143.4 0.0 14.4 2.5 28.3 13.3 11.3 22.8 12.0 74.4 48.9 3.7 12.1 102.4 52.9 24.1 14.8 12.1 0.2 10.3 10.1 172.0 126.8 24.4 17.9 6.2 4.2 9.3 17.2 8.8 62.8 16.3 8.1 5.2 71.4 54.1 39.9 50.0 5.3 6.6 52.8 63.7 10.0 17.4 25.5 13.1 16.1 11.7 3.8 5.5 14.9 1.1 0.8 9.9 13.1 48.6 19.4 GASK1B "C4orf18, DKFZp434L142, ENED, FAM198B, FLJ38155" ENSG00000164125 "Golgi associated kinase 1B" Q6UWH4 4 158124474-158173318 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 206.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.9;Cardiomyocytes: 33.8;Endothelial cells: 12.1;Fibroblasts: 14.5;Hofbauer cells: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "classical monocyte: 50.6;intermediate monocyte: 28.8;myeloid DC: 15.1;non-classical monocyte: 14.0" "Group enriched" "Detected in many" 41 "dendritic cells: 15.1;monocytes: 50.6" "Cell line enhanced" "Detected in many" "ASC diff: 77.0;ASC TERT1: 143.3;HSkMC: 166.4;HUVEC TERT2: 193.3;WM-115: 74.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007227 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA 13000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA007227: AB_1847689" "unprognostic (4.87e-2)" "unprognostic (7.79e-2)" "unprognostic (6.60e-3)" "unprognostic (9.42e-3)" "unprognostic (2.37e-2)" "unprognostic (7.47e-2)" "unprognostic (2.13e-2)" "unprognostic (7.49e-2)" "unprognostic (9.20e-3)" "unprognostic (1.71e-1)" "unprognostic (1.60e-1)" "unprognostic (1.89e-1)" "unprognostic (3.25e-3)" "unprognostic (3.74e-3)" "unprognostic (3.85e-2)" "unprognostic (1.14e-2)" "unprognostic (1.89e-2)" 73.9 206.2 29.0 39.8 29.2 2.8 47.3 21.8 23.3 47.0 11.9 23.4 13.3 77.7 21.8 17.2 19.4 37.1 77.9 28.7 29.6 9.5 8.6 14.1 11.2 51.7 33.0 140.3 14.2 11.5 2.8 29.0 26.9 23.6 23.3 0.8 23.6 30.0 12.4 7.3 18.5 70.2 34.1 20.8 11.8 10.4 35.5 5.7 17.7 16.7 6.8 43.2 9.2 33.0 12.5 9.9 6.1 1.1 77.0 143.3 11.4 3.1 2.4 0.6 3.7 13.3 4.9 0.1 0.3 5.0 5.1 0.2 70.7 18.9 1.8 0.1 0.2 1.0 0.0 37.0 51.4 0.6 0.3 166.4 4.6 24.2 2.6 8.0 193.3 0.0 13.0 0.0 35.7 0.8 0.0 0.2 0.4 43.4 0.2 0.1 0.5 0.2 0.0 27.5 0.4 0.1 0.0 27.8 8.2 33.4 5.4 0.3 9.3 16.0 17.1 9.6 6.1 0.0 0.1 44.8 2.5 0.3 74.3 0.1 50.6 0.0 0.1 28.8 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.7 0.1 14.0 0.6 0.0 17.8 29.0 29.2 21.8 23.3 28.7 29.6 51.7 33.0 26.9 34.1 35.5 33.0 22.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 1.2 14.5 0.0 0.0 0.0 0.0 0.0 0.0 67.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 GBF1 "ARF1GEF, KIAA0248" ENSG00000107862 "Golgi brefeldin A resistant guanine nucleotide exchange factor 1" Q92538 10 102245371-102382899 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 28.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037759, HPA037760" Uncertain Supported "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA037759: AB_10671884, HPA037760: AB_2675651" "unprognostic (5.97e-2)" "unprognostic (3.33e-1)" "unprognostic (2.74e-3)" "unprognostic (7.02e-2)" "unprognostic (2.03e-1)" "unprognostic (6.72e-2)" "unprognostic (3.78e-2)" "unprognostic (8.28e-2)" "unprognostic (1.12e-2)" "unprognostic (5.34e-3)" "unprognostic (2.04e-2)" "unprognostic (6.06e-2)" "unprognostic (1.87e-1)" "unprognostic (2.10e-1)" "unprognostic (2.24e-1)" "unprognostic (3.02e-1)" "unprognostic (3.09e-2)" 19.4 21.1 31.5 16.0 31.7 25.0 19.3 28.7 47.2 21.7 34.9 24.6 20.6 23.5 12.7 21.9 19.7 9.8 30.0 32.2 27.7 21.7 23.2 20.5 14.6 28.5 37.3 21.6 25.6 24.4 31.5 11.5 30.6 24.2 13.9 19.2 24.5 15.2 48.1 24.9 25.8 16.4 27.1 21.7 21.2 20.5 29.8 11.8 25.4 30.1 13.8 21.7 20.5 29.1 19.4 49.7 23.3 25.1 62.9 40.7 28.1 37.7 56.0 45.3 48.1 52.7 35.1 21.7 29.7 59.6 33.8 38.6 45.9 52.8 33.8 35.4 36.9 33.3 38.1 44.6 26.4 35.2 46.8 37.3 28.0 60.7 57.5 77.2 45.2 22.5 20.7 53.7 41.8 36.9 24.2 38.9 15.4 29.5 35.6 33.6 72.1 18.8 39.3 30.9 15.0 16.3 30.2 22.3 26.5 33.1 50.4 30.8 60.5 29.1 29.6 37.7 55.6 32.4 36.3 26.5 30.0 36.3 22.1 28.6 4.5 4.3 4.9 5.0 5.9 6.5 3.6 6.5 5.0 3.9 5.7 5.3 4.6 4.6 4.1 4.2 7.4 3.9 31.5 31.7 28.7 47.2 32.2 27.7 28.5 37.3 30.6 27.1 29.8 29.1 12.5 12.8 10.1 56.5 15.5 9.8 5.5 10.6 17.6 24.7 15.7 12.8 17.0 15.7 10.9 12.9 56.3 12.2 15.1 31.4 3.9 12.5 4.9 14.3 18.1 12.3 12.0 13.9 72.1 16.7 16.3 14.6 31.1 15.6 7.6 10.3 8.2 17.6 12.2 52.2 73.0 21.9 12.2 11.0 5.0 4.7 10.2 13.4 12.4 66.5 9.5 11.1 9.2 80.9 71.1 18.6 20.7 11.3 46.0 7.7 27.1 9.0 12.3 41.0 6.6 21.7 12.3 36.0 25.4 20.7 13.1 17.6 16.0 19.1 19.4 6.7 GIMAP1 "HIMAP1, IAN2, IMAP1, IMAP38" ENSG00000213203 "GTPase, IMAP family member 1" Q8WWP7 7 150716606-150724284 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.7" "Cell type enhanced" "Detected in many" "Adipocytes: 189.8;Endothelial cells: 109.9;Hepatic stellate cells: 117.8;Kupffer cells: 109.1;monocytes: 74.9;NK-cells: 185.3;T-cells: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 14.7;MOLT-4: 9.2;TIME: 3.9" "Low region specificity" "Detected in many" "HPA044887, HPA053441" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA044887: AB_10960351, HPA053441: AB_2682152" "unprognostic (1.60e-2)" "unprognostic (6.58e-3)" "unprognostic (8.21e-3)" "unprognostic (2.54e-3)" "unprognostic (1.10e-1)" "unprognostic (2.33e-3)" "prognostic favorable (1.09e-4)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (3.44e-1)" "unprognostic (4.60e-3)" "unprognostic (7.89e-2)" "unprognostic (1.77e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.12e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-1)" 9.8 2.5 3.0 11.0 3.0 1.0 7.9 2.9 3.5 3.8 3.0 3.7 3.5 4.6 1.1 2.1 4.4 3.2 9.3 2.8 2.9 3.5 2.4 8.9 19.6 3.5 3.2 1.5 1.4 1.5 1.1 7.1 3.4 2.3 2.2 0.1 2.5 2.0 5.4 2.5 6.9 3.8 3.5 24.7 3.3 0.8 3.6 6.6 5.3 7.1 8.4 3.5 3.0 3.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.7 1.9 0.0 0.0 0.0 0.0 9.2 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 3.0 32.2 0.1 43.8 29.6 51.1 0.3 47.5 54.2 13.5 0.6 68.2 56.2 2.7 42.6 30.6 0.8 34.0 35.0 3.0 3.0 2.9 3.5 2.8 2.9 3.5 3.2 3.4 3.5 3.6 3.2 189.8 3.2 1.5 0.0 5.1 5.5 0.6 0.0 1.2 0.6 1.9 3.6 5.9 2.8 0.6 0.0 0.0 0.3 51.5 0.1 0.0 0.3 0.3 0.4 0.6 109.9 0.0 10.5 0.0 0.4 0.3 3.7 1.5 0.2 8.2 0.2 117.8 2.0 37.9 0.0 0.0 0.0 0.0 109.1 7.6 1.3 1.5 48.0 8.8 0.0 74.9 0.3 185.3 0.0 0.0 0.1 0.1 0.0 7.6 0.7 0.2 0.5 0.0 1.0 0.0 2.5 3.5 0.3 0.5 0.7 3.1 0.4 97.3 1.0 0.0 0.7 GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.7" "Cell type enhanced" "Detected in many" "Adipocytes: 182.3;Endothelial cells: 195.2;Hepatic stellate cells: 222.0;Kupffer cells: 197.2;Macrophages: 110.0;monocytes: 176.0;NK-cells: 344.0;T-cells: 186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 26 "HUVEC TERT2: 326.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" 46.1 18.3 15.0 75.1 15.6 4.2 31.8 16.2 21.2 19.7 16.3 21.2 16.5 23.0 9.6 12.0 18.7 24.6 31.3 14.3 16.0 17.3 29.9 50.8 127.7 19.2 18.0 7.7 6.7 9.6 6.0 48.7 18.0 10.2 22.4 1.5 11.2 13.3 17.5 8.4 25.0 38.3 18.8 115.6 18.0 4.2 16.4 30.5 21.1 48.1 85.1 31.1 11.6 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 326.4 3.4 0.1 0.3 0.0 0.0 0.4 0.2 0.4 0.0 0.0 12.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 370.2 5.2 325.8 390.9 404.2 3.0 408.0 402.8 122.1 1.3 424.3 361.9 339.7 263.4 320.4 5.3 312.1 776.9 15.0 15.6 16.2 21.2 14.3 16.0 19.2 18.0 18.0 18.8 16.4 18.7 182.3 3.2 12.4 0.3 7.3 6.8 0.2 0.0 3.4 0.1 2.2 4.7 9.9 5.7 1.8 11.0 0.0 0.6 82.6 0.0 0.0 0.2 0.6 0.3 0.4 195.2 0.0 9.7 0.5 0.2 0.8 9.0 2.0 0.3 6.3 0.0 222.0 3.7 96.4 0.0 0.1 0.0 0.0 197.2 20.9 1.7 5.0 110.0 10.6 18.7 176.0 0.2 344.0 0.0 0.1 0.1 0.0 0.0 14.7 0.4 0.0 1.9 0.7 0.4 13.1 3.9 7.9 0.0 0.8 1.1 6.1 0.8 186.2 0.8 0.0 0.3 GIMAP6 "FLJ22690, IAN6" ENSG00000133561 "GTPase, IMAP family member 6" Q6P9H5 7 150625375-150632648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 95.3;Endothelial cells: 83.5;Hepatic stellate cells: 92.1;Kupffer cells: 75.2;monocytes: 37.4;NK-cells: 91.6;T-cells: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "monocytes: 75.1;NK-cells: 217.3;T-cells: 127.2" "Cell line enhanced" "Detected in some" "HMC-1: 18.4;HUVEC TERT2: 124.9;MOLT-4: 43.3;TIME: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026715, HPA050740" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA026715: AB_1849675, HPA050740: AB_2797239" "unprognostic (8.58e-2)" "unprognostic (1.34e-2)" "unprognostic (6.56e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.22e-1)" "prognostic favorable (2.91e-4)" "prognostic favorable (1.56e-4)" "unprognostic (2.88e-2)" "unprognostic (8.75e-2)" "unprognostic (8.87e-2)" "unprognostic (4.68e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.75e-1)" "unprognostic (2.48e-2)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" 42.0 9.4 9.7 33.9 9.7 2.5 21.8 9.7 10.6 14.9 8.0 12.0 13.6 19.3 7.3 8.4 16.9 14.7 29.1 8.0 9.5 12.4 12.7 38.8 50.2 11.4 10.5 5.7 5.2 8.0 3.3 32.3 11.3 6.4 12.2 0.6 7.8 10.0 24.7 6.4 18.7 25.8 10.9 64.0 11.6 3.2 11.6 29.3 14.2 34.7 33.9 16.5 6.5 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 3.8 0.0 6.3 0.0 0.0 0.0 0.4 18.4 0.1 0.0 0.0 0.0 0.0 124.9 0.5 0.0 4.6 0.0 0.0 43.3 5.4 0.0 0.0 0.0 4.6 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.8 35.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 13.0 0.0 11.6 58.1 2.1 112.9 75.1 127.2 0.4 104.3 120.2 22.1 0.3 108.3 103.0 8.0 217.3 60.2 0.7 105.7 163.5 9.7 9.7 9.7 10.6 8.0 9.5 11.4 10.5 11.3 10.9 11.6 10.1 95.3 0.0 1.1 0.0 3.1 3.8 0.1 0.0 0.6 0.0 1.1 1.0 7.4 0.0 0.0 0.0 0.0 0.2 24.5 0.1 0.0 0.0 0.4 0.1 0.2 83.5 0.0 19.4 0.0 0.2 0.3 3.4 0.0 0.2 2.5 0.3 92.1 1.7 30.6 0.0 0.0 0.1 0.0 75.2 6.5 2.2 1.2 20.0 1.8 13.1 37.4 0.1 91.6 0.0 0.1 0.1 0.0 0.0 2.9 0.1 0.0 0.2 0.7 0.4 0.0 2.6 2.2 0.3 0.1 0.4 3.1 0.4 41.2 1.2 0.0 0.3 GIMAP8 "DKFZp667I133, hIAN6, IAN9" ENSG00000171115 "GTPase, IMAP family member 8" Q8ND71 7 150450630-150479393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.6" "Cell type enhanced" "Detected in many" "Adipocytes: 67.4;Endothelial cells: 66.0;Hepatic stellate cells: 86.0;Kupffer cells: 75.1;Microglial cells: 32.8;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 59.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014474, HPA017765" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA014474: AB_1849685, HPA017765: AB_1849683" "unprognostic (7.86e-2)" "unprognostic (7.87e-3)" "unprognostic (1.04e-1)" "unprognostic (4.42e-3)" "unprognostic (2.11e-1)" "unprognostic (8.09e-3)" "unprognostic (1.07e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (8.07e-2)" "unprognostic (6.26e-3)" "unprognostic (2.15e-1)" "unprognostic (1.04e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" 20.3 5.7 4.4 21.3 5.0 0.7 16.0 4.7 5.5 9.8 5.5 6.7 6.8 10.4 3.1 4.3 9.0 7.5 17.4 4.1 4.5 8.3 9.4 27.0 23.2 5.4 4.9 3.5 2.8 4.6 2.6 15.4 5.4 4.9 7.2 0.3 4.3 5.3 9.8 4.7 10.5 12.7 5.4 40.6 5.0 2.0 5.1 7.3 11.9 15.1 13.5 8.4 5.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 59.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.7 0.0 9.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.5 45.2 0.0 15.3 59.0 17.4 0.5 14.8 13.9 13.0 0.0 16.7 13.6 4.8 15.5 57.4 0.7 7.7 26.8 4.4 5.0 4.7 5.5 4.1 4.5 5.4 4.9 5.4 5.4 5.1 5.8 67.4 3.2 5.3 0.3 0.8 3.1 0.5 0.0 1.8 0.0 0.4 0.8 5.5 5.7 0.0 1.8 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.2 0.1 66.0 0.0 1.3 0.1 0.0 0.0 2.3 0.5 0.2 3.8 0.0 86.0 1.6 6.8 0.0 0.1 0.0 0.0 75.1 2.8 0.9 0.3 21.9 0.0 32.8 44.2 0.0 19.6 0.0 0.1 0.0 0.0 0.0 2.2 0.9 0.0 0.2 1.5 0.0 0.0 1.5 1.2 0.2 0.4 0.5 1.7 0.1 11.1 0.2 0.0 0.4 GLCE "HSEPI, KIAA0836" ENSG00000138604 "Glucuronic acid epimerase" O94923 15 69160584-69272217 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 79.0;Microglial cells: 76.8;Oligodendrocytes: 154.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 35.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 1.9;monocytes: 2.3;T-cells: 2.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 119.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040481, HPA048216" Uncertain Approved Mitochondria "Intracellular and membrane" NA NA 240000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA040481: AB_2677004, HPA048216: AB_2680317" "unprognostic (1.30e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-3)" "unprognostic (7.77e-2)" "unprognostic (1.58e-1)" "unprognostic (5.55e-3)" "unprognostic (1.00e-1)" "unprognostic (2.84e-1)" "unprognostic (1.48e-1)" "unprognostic (2.56e-1)" "unprognostic (7.47e-2)" "unprognostic (1.41e-1)" "unprognostic (2.40e-2)" "unprognostic (1.53e-1)" "unprognostic (6.00e-2)" "unprognostic (5.23e-1)" "unprognostic (4.07e-2)" 9.1 12.2 6.7 5.6 7.8 0.9 8.9 35.8 6.2 8.2 8.4 12.8 14.2 6.4 6.9 10.0 5.5 7.5 6.3 6.0 6.7 13.3 16.8 8.4 3.5 5.7 8.5 12.7 4.7 8.7 6.4 13.4 7.2 5.8 14.2 13.2 10.9 5.8 4.1 10.4 11.5 7.0 7.5 4.4 9.1 3.9 8.8 4.9 4.1 4.9 5.1 6.6 4.6 8.0 9.6 8.5 5.6 9.7 18.6 17.6 2.0 17.6 23.2 13.3 25.2 7.1 23.6 5.8 8.5 14.4 16.8 14.0 12.1 11.4 27.1 2.2 13.4 9.7 15.0 7.2 17.9 4.2 19.0 12.1 7.8 16.6 18.6 9.7 119.4 4.3 3.9 6.0 25.4 5.9 2.6 7.4 2.7 9.7 5.9 5.8 22.6 7.3 12.3 10.1 17.9 3.7 18.0 11.0 38.1 3.8 7.9 5.8 41.8 12.7 15.7 14.3 15.8 2.5 3.7 1.3 12.9 7.0 18.8 0.0 2.1 0.0 0.3 1.6 0.5 0.2 0.8 0.4 1.8 0.2 0.5 0.7 0.0 0.2 2.3 1.9 2.0 0.9 6.7 7.8 35.8 6.2 6.0 6.7 5.7 8.5 7.2 7.5 8.8 8.0 16.9 0.0 15.4 4.9 6.2 4.8 10.1 8.3 26.2 10.3 18.8 19.4 8.1 7.2 8.8 11.0 10.4 22.7 12.1 21.3 5.9 13.0 3.9 4.0 5.4 22.6 20.4 9.4 79.0 13.8 12.7 14.0 28.1 4.9 2.5 11.8 16.4 27.2 16.4 8.4 41.5 27.1 10.2 13.3 4.4 5.1 6.2 10.7 8.8 76.8 13.7 13.1 4.1 35.7 154.9 16.9 28.2 17.7 7.1 5.3 32.4 18.3 18.2 16.6 13.1 6.6 9.4 29.8 25.9 27.9 6.5 33.0 5.9 17.1 26.4 13.3 GLIPR2 "C9orf19, GAPR-1" ENSG00000122694 "GLI pathogenesis related 2" Q9H4G4 9 36136536-36163913 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 188.5;Langerhans cells: 203.6;Macrophages: 117.6;monocytes: 203.0;NK-cells: 180.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 71.6;HDLM-2: 72.9;TIME: 127.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029478 Approved Uncertain Vesicles,Microtubules NA NA 19000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Microtubules "HPA029478: AB_10670038" "unprognostic (1.57e-2)" "unprognostic (5.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.46e-2)" "unprognostic (1.33e-2)" "unprognostic (9.90e-2)" "unprognostic (2.50e-1)" "unprognostic (1.84e-2)" "unprognostic (4.26e-2)" "unprognostic (3.21e-1)" "unprognostic (5.87e-2)" "prognostic unfavorable (6.54e-7)" "unprognostic (6.57e-3)" "unprognostic (4.94e-1)" "unprognostic (1.02e-1)" "unprognostic (2.43e-2)" 38.5 20.9 17.6 52.7 22.8 73.8 32.4 21.0 22.6 45.9 14.1 73.7 14.7 77.8 15.1 18.6 36.9 24.1 24.2 17.2 19.3 8.8 6.9 62.6 29.9 24.8 22.1 13.3 5.6 2.5 4.9 8.8 22.3 38.3 33.1 2.7 15.3 39.3 7.7 12.2 32.2 63.8 22.8 41.3 25.3 3.4 26.7 18.7 15.8 11.1 19.2 38.8 27.4 27.6 3.7 2.9 20.9 22.3 71.6 33.3 2.4 32.9 20.0 7.8 14.1 1.3 0.3 0.2 10.2 30.9 19.7 0.2 7.9 1.1 4.7 72.9 6.4 8.8 6.2 0.4 27.9 5.7 28.3 23.4 1.0 44.5 7.8 14.0 62.5 22.6 0.4 5.0 17.4 7.9 27.9 15.2 20.1 0.3 10.7 18.9 44.1 1.0 1.6 1.8 5.6 11.3 4.4 2.2 3.6 42.2 2.3 24.0 127.3 10.7 24.8 9.6 28.0 7.8 2.2 12.7 11.0 35.0 2.5 268.6 360.9 540.3 168.4 162.5 89.1 24.4 114.3 108.2 208.3 24.5 47.0 74.7 657.0 125.5 124.9 18.5 132.2 414.0 17.6 22.8 21.0 22.6 17.2 19.3 24.8 22.1 22.3 22.8 26.7 27.6 11.9 3.2 25.4 4.6 22.3 13.4 2.5 14.7 1.8 0.3 46.9 19.0 2.6 2.8 30.9 5.5 0.0 3.8 66.9 14.7 0.0 21.2 0.7 1.8 33.9 13.3 8.4 58.7 1.1 1.3 3.3 54.3 11.7 2.1 52.6 1.9 16.1 0.9 188.5 0.0 0.8 42.4 14.2 83.2 203.6 2.3 18.0 117.6 62.2 2.8 203.0 21.4 180.2 3.0 28.6 5.2 16.1 25.9 22.8 16.0 4.0 1.1 64.3 0.5 46.0 44.7 43.2 0.9 6.4 0.9 10.2 3.4 75.5 10.9 45.3 3.3 GNAI2 "GIP, GNAI2B" ENSG00000114353 "G protein subunit alpha i2" P04899 3 50226292-50259362 "Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 656.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007704 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 4000000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Cytosol "Nucleoplasm, Plasma membrane" "HPA007704: AB_1849230" "prognostic favorable (1.03e-4)" "unprognostic (3.89e-1)" "unprognostic (3.35e-2)" "unprognostic (8.40e-3)" "unprognostic (2.58e-1)" "unprognostic (2.32e-2)" "unprognostic (2.59e-2)" "unprognostic (3.23e-1)" "unprognostic (1.08e-3)" "unprognostic (6.01e-2)" "unprognostic (7.00e-3)" "unprognostic (1.12e-1)" "unprognostic (6.24e-3)" "unprognostic (1.44e-1)" "unprognostic (4.30e-2)" "unprognostic (4.33e-2)" "unprognostic (1.38e-1)" 210.2 100.3 155.2 217.9 167.3 367.1 152.8 166.3 181.6 146.0 120.2 142.1 69.9 141.7 66.9 124.4 136.9 152.5 157.1 144.3 184.6 79.4 126.5 214.5 251.3 199.8 170.2 147.7 64.1 66.9 99.2 241.8 194.8 103.6 64.3 35.6 71.9 156.9 69.3 87.0 103.0 154.0 173.6 262.1 73.6 69.6 173.3 160.3 101.3 89.4 170.4 169.7 108.4 193.2 128.2 63.0 186.3 197.6 220.7 277.5 35.5 271.1 399.6 354.9 361.1 70.4 173.2 149.1 119.2 567.0 193.4 100.1 132.8 350.3 222.8 331.2 50.9 364.8 158.0 110.2 219.8 329.2 479.8 270.3 152.9 319.1 129.8 289.6 837.8 124.1 26.1 307.1 357.5 155.7 313.6 433.0 109.7 59.0 302.4 185.0 89.8 219.7 232.6 130.9 48.4 86.1 189.5 57.1 124.4 150.4 94.3 346.1 792.3 330.9 187.5 309.2 274.7 199.4 278.3 127.0 373.6 466.9 398.1 16.6 59.3 113.7 33.7 80.9 20.2 28.8 26.8 34.3 57.3 26.1 20.2 25.8 145.2 23.5 74.5 47.2 34.0 27.3 155.2 167.3 166.3 181.6 144.3 184.6 199.8 170.2 194.8 173.6 173.3 193.2 656.8 41.7 32.1 25.1 119.5 56.7 59.7 32.3 45.5 29.0 61.6 83.8 22.9 55.8 26.6 44.1 14.6 79.5 311.4 11.7 5.9 124.3 203.3 57.8 115.7 340.3 92.2 52.1 12.4 60.5 84.4 101.9 21.9 71.8 89.9 150.0 221.3 79.7 336.0 6.7 14.8 24.6 18.3 342.7 291.7 302.0 90.7 386.1 83.6 58.1 356.6 292.6 151.4 26.7 45.4 160.3 40.9 95.5 104.8 46.1 30.3 24.5 24.4 21.9 52.6 85.3 163.1 16.6 22.6 37.6 62.9 116.4 164.9 156.3 20.5 70.1 GNAT2 ACHM4 ENSG00000134183 "G protein subunit alpha transducin 2" P19087 1 109603091-109619929 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "retina: 78.8" "Cell type enriched" "Detected in some" 8 "Cone photoreceptor cells: 60.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 2.3;eosinophil: 2.5;neutrophil: 3.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.7" "Cell line enhanced" "Detected in some" "CACO-2: 4.5;TIME: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 79: Retina - Phototransduction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" 0.0 0.1 0.4 0.5 0.8 0.4 0.0 0.8 1.1 0.0 3.6 0.1 0.0 0.2 0.0 0.2 0.1 1.0 0.9 0.9 0.1 0.2 0.9 0.1 0.3 0.3 0.2 0.0 0.9 0.2 0.2 0.5 0.6 0.1 0.1 78.8 0.3 0.1 0.2 1.8 0.7 0.1 0.0 0.2 0.2 2.7 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.3 0.7 0.7 0.5 1.1 0.1 0.1 0.3 0.7 0.1 0.2 0.0 4.5 0.4 1.3 1.8 0.0 0.3 0.4 1.8 0.1 0.3 0.3 0.4 1.2 1.8 0.7 0.0 1.5 0.8 0.4 0.2 0.7 0.3 1.0 0.4 0.5 0.6 0.7 0.2 1.1 0.5 0.4 0.6 0.6 0.4 0.5 0.8 0.8 0.2 2.0 1.2 0.5 1.3 0.4 1.7 2.7 0.9 0.0 5.9 0.3 0.4 1.3 2.5 1.4 2.9 1.7 2.8 0.5 0.5 2.3 0.5 2.5 0.6 0.4 0.6 0.5 0.4 0.4 0.4 0.4 0.4 0.4 3.7 0.4 0.6 0.5 0.3 0.1 0.4 0.8 0.8 1.1 0.9 0.1 0.3 0.2 0.6 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 60.5 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.1 0.0 2.8 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GNG11 GNGT11 ENSG00000127920 "G protein subunit gamma 11" P61952 7 93921735-93928610 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Adipocytes: 1903.6;Endothelial cells: 1236.2;Hepatic stellate cells: 994.2;Macrophages: 481.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 20.5;neutrophil: 9.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.5" "Cell line enhanced" "Detected in many" "EFO-21: 219.9;HUVEC TERT2: 349.6;SK-MEL-30: 221.8;TIME: 201.1;U-87 MG: 187.1" "Low region specificity" "Detected in all" HPA045255 Uncertain NA NA 3400000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "HPA045255: AB_10794781" "unprognostic (1.30e-1)" "unprognostic (8.04e-2)" "unprognostic (2.53e-1)" "unprognostic (4.89e-3)" "unprognostic (4.94e-2)" "unprognostic (2.63e-2)" "unprognostic (2.58e-2)" "unprognostic (3.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (1.42e-1)" "unprognostic (2.62e-2)" "unprognostic (1.91e-2)" "unprognostic (2.14e-3)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" "unprognostic (4.71e-3)" 75.5 16.8 14.4 8.1 14.6 2.5 64.4 14.7 22.0 24.9 13.7 23.5 6.7 26.8 10.9 10.9 33.5 15.5 48.3 14.1 14.7 34.9 12.1 39.8 7.8 14.9 14.6 56.7 8.8 4.4 9.3 85.9 15.3 15.8 6.4 1.5 9.1 17.9 15.4 11.4 16.1 16.7 15.1 39.0 16.0 3.3 16.1 19.0 29.1 18.6 3.5 27.9 18.4 14.9 0.2 34.2 67.2 31.0 51.2 40.0 0.0 34.8 67.7 19.0 26.7 0.1 2.9 0.0 219.9 17.5 79.9 0.5 0.5 3.2 23.8 0.2 2.0 11.0 35.9 0.0 81.8 0.0 0.1 13.4 0.1 61.0 6.0 78.7 349.6 0.0 0.1 0.2 85.9 0.0 0.1 0.1 5.8 0.0 10.4 32.5 7.6 0.1 41.3 0.0 0.1 67.2 0.0 0.2 221.8 8.6 144.4 2.4 201.1 93.4 10.4 68.3 3.9 0.0 0.2 0.7 187.1 0.0 81.8 20.5 0.7 0.3 0.1 0.1 0.2 2.3 0.0 0.0 1.0 2.0 0.2 0.0 9.8 0.0 0.1 3.7 0.1 50.2 14.4 14.6 14.7 22.0 14.1 14.7 14.9 14.6 15.3 15.1 16.1 14.9 1903.6 12.8 27.3 1.3 20.6 83.6 11.8 3.1 5.7 0.7 15.2 26.8 94.8 11.5 3.1 187.6 0.0 2.3 15.4 0.1 74.3 135.7 5.9 124.1 94.6 1236.2 0.0 40.6 0.0 5.7 12.9 207.3 0.5 236.4 2.5 12.7 994.2 11.1 17.0 0.0 0.0 0.3 18.3 55.9 89.5 17.0 82.3 481.1 188.5 26.2 49.6 9.2 41.2 0.5 0.2 4.3 0.0 86.9 8.0 11.0 0.0 12.9 1.7 4.7 151.2 115.5 165.0 1.9 7.6 2.7 65.8 23.8 15.9 109.9 0.0 4.5 GNG12 ENSG00000172380 "G protein subunit gamma 12" Q9UBI6 1 67701475-67833467 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057790, HPA062208" Enhanced Supported Approved Mitochondria NA NA 550000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA057790: AB_2683527, HPA062208: AB_2684711" "unprognostic (5.18e-2)" "unprognostic (1.76e-3)" "unprognostic (4.46e-3)" "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (4.71e-2)" "unprognostic (5.29e-2)" "unprognostic (5.84e-3)" "unprognostic (5.50e-2)" "unprognostic (3.41e-2)" "unprognostic (4.46e-3)" "unprognostic (8.13e-2)" "unprognostic (4.12e-3)" "unprognostic (2.33e-2)" "unprognostic (9.33e-2)" "unprognostic (7.78e-2)" "unprognostic (2.14e-3)" 63.4 57.0 14.4 28.5 12.3 0.3 50.1 10.4 14.0 59.3 13.5 68.4 122.0 59.7 27.7 82.0 43.4 59.3 34.5 13.7 19.5 79.2 44.8 34.3 12.0 21.9 29.1 47.9 25.2 54.7 13.1 60.2 16.9 38.3 65.7 6.6 26.6 47.6 12.9 80.4 110.8 73.9 18.6 56.2 42.7 17.7 16.4 15.9 59.8 19.7 22.7 56.5 46.5 18.7 60.5 55.5 58.0 31.5 241.2 207.9 59.5 182.9 237.2 157.9 141.0 26.5 58.2 0.1 75.9 258.0 98.8 44.2 36.6 150.0 275.7 0.5 28.1 1.0 46.0 0.1 96.0 0.1 3.0 125.7 87.8 168.7 221.8 221.1 251.9 0.0 3.6 0.3 175.6 10.2 0.1 0.5 44.1 65.7 68.3 0.3 119.6 0.9 151.8 53.5 13.2 26.8 126.8 52.1 248.4 48.8 26.9 1.1 326.7 182.5 118.8 332.0 114.5 3.0 0.3 0.5 115.3 7.1 252.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 12.3 10.4 14.0 13.7 19.5 21.9 29.1 16.9 18.6 16.4 18.7 49.7 54.5 32.2 54.5 2.1 201.3 78.8 53.3 78.6 2.1 52.4 37.1 26.7 35.8 42.8 58.8 6.2 61.8 0.9 243.1 74.3 96.2 14.6 51.8 20.6 67.0 34.7 5.3 0.5 138.5 105.6 82.6 45.3 49.3 3.8 21.3 76.1 45.6 27.9 3.3 15.3 56.3 30.5 18.2 32.4 16.6 71.4 6.2 78.2 21.5 3.6 3.0 0.0 63.3 1.3 143.7 99.9 75.6 0.2 119.9 227.3 177.9 79.2 18.9 52.6 54.8 71.7 1.8 18.8 83.1 216.8 175.9 4.5 107.1 61.8 109.1 GPR150 PGR11 ENSG00000178015 "G protein-coupled receptor 150" Q8NGU9 5 95620087-95622142 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;pancreas: 6.9" "Cell type enhanced" "Detected in some" "Early spermatids: 4.0;Extravillous trophoblasts: 5.3;granulocytes: 5.7;Hofbauer cells: 3.5;NK-cells: 2.1;Spermatocytes: 2.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.4;SiHa: 1.2;TIME: 2.7" "Low region specificity" "Detected in some" HPA026635 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA026635: AB_1849266" "unprognostic (3.03e-2)" "unprognostic (6.88e-3)" "unprognostic (1.01e-1)" "unprognostic (1.01e-2)" "unprognostic (5.95e-2)" "unprognostic (5.34e-4)" "unprognostic (1.98e-2)" "unprognostic (6.36e-2)" "unprognostic (3.13e-1)" "unprognostic (1.17e-2)" "unprognostic (1.94e-3)" "unprognostic (1.88e-2)" "unprognostic (1.76e-1)" "unprognostic (3.23e-2)" "unprognostic (4.42e-2)" "unprognostic (3.55e-2)" "unprognostic (1.26e-1)" 0.9 0.1 1.9 0.0 2.7 0.0 0.7 0.0 2.6 0.3 0.0 0.3 0.1 0.2 0.1 0.1 0.3 0.1 0.1 2.5 0.8 0.0 0.1 0.3 0.3 0.0 0.0 0.0 6.9 1.2 0.6 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.2 0.6 0.3 0.0 0.0 0.4 1.6 0.2 2.2 0.1 0.1 0.0 0.1 0.3 0.2 1.8 0.0 0.0 0.0 0.0 1.4 0.6 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.8 0.5 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.5 1.2 0.0 0.3 0.0 0.0 0.4 2.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.9 2.7 0.0 2.6 2.5 0.8 0.0 0.0 0.0 0.0 2.2 1.8 0.5 0.0 0.6 0.0 0.9 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 4.0 0.1 0.1 0.2 0.0 0.4 0.0 0.2 5.3 0.9 0.0 0.0 5.7 0.0 0.4 0.5 3.5 0.0 0.0 0.3 0.0 0.3 0.3 1.1 0.0 0.9 0.0 0.0 0.7 0.0 2.1 0.0 0.0 0.2 0.7 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.3 2.5 0.5 0.1 0.3 0.0 1.4 0.0 0.8 0.1 GPR17 ENSG00000144230 "G protein-coupled receptor 17" Q13304 2 127645864-127652639 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 19.8;intestine: 23.8" "Cell type enriched" "Detected in some" 58 "Oligodendrocyte precursor cells: 58.3" "Cancer enriched" "Detected in some" 32 "glioma: 16.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "naive B-cell: 1.9" "Lineage enriched" "Detected in single" 19 "B-cells: 1.9" "Cell line enhanced" "Detected in some" "HeLa: 3.1;REH: 4.4;TIME: 4.3;U-2 OS: 1.7;U-2197: 2.0;U-251 MG: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029766 Enhanced Supported Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA029766: AB_10612114" "unprognostic (8.10e-2)" "unprognostic (1.73e-1)" "unprognostic (2.61e-1)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (5.19e-2)" "unprognostic (2.77e-5)" "unprognostic (8.40e-3)" "unprognostic (2.92e-1)" "unprognostic (3.25e-2)" "unprognostic (1.61e-3)" "unprognostic (6.60e-2)" "unprognostic (2.11e-3)" "unprognostic (3.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" 9.8 1.1 9.1 3.4 6.3 0.1 7.9 4.7 9.7 3.6 3.5 23.8 1.5 14.8 1.4 2.4 5.3 2.1 19.8 6.4 5.5 3.0 2.6 9.3 1.1 7.2 7.5 1.8 2.2 0.0 0.7 1.2 7.2 5.5 0.1 0.1 2.0 0.0 7.5 3.4 6.0 0.0 6.4 7.5 5.8 0.9 7.7 0.1 3.8 0.2 0.0 8.8 5.0 8.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.1 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 4.4 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 1.2 0.1 0.0 4.3 0.0 1.7 2.0 2.6 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 6.3 4.7 9.7 6.4 5.5 7.2 7.5 7.2 6.4 7.7 8.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 58.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602212 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.6" "Cell type enhanced" "Detected in some" "Adipocytes: 26.7;Endothelial cells: 26.4;Hepatic stellate cells: 24.7;Sertoli cells: 6.6;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HUVEC TERT2: 18.7;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014278 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA014278: AB_1849300" "unprognostic (2.49e-2)" "unprognostic (6.62e-3)" "unprognostic (1.33e-2)" "unprognostic (2.93e-2)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (4.66e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" "unprognostic (9.18e-2)" "unprognostic (2.49e-3)" 40.6 6.9 7.0 3.3 6.2 0.5 22.1 6.0 8.8 4.9 6.2 4.2 0.9 7.4 0.7 2.6 6.0 3.3 23.8 5.6 5.9 24.6 3.6 28.6 0.9 8.0 7.5 3.5 3.7 1.4 5.9 4.0 8.6 5.8 0.7 0.9 2.9 0.9 5.7 2.9 5.1 2.5 6.5 4.1 5.6 1.7 10.7 0.5 18.2 2.5 0.6 7.0 4.9 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.7 0.7 1.1 0.0 0.1 0.0 2.0 0.1 0.0 0.1 0.0 0.1 1.3 0.2 0.1 0.0 0.1 0.0 0.5 0.0 0.8 0.0 0.0 0.3 0.3 0.0 18.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 31.3 0.1 1.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 6.2 6.0 8.8 5.6 5.9 8.0 7.5 8.6 6.5 10.7 6.3 26.7 0.0 0.5 0.7 0.1 2.4 0.2 0.0 1.2 0.1 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.1 0.3 26.4 0.0 0.0 0.1 0.0 0.0 1.5 2.0 0.2 0.0 0.0 24.7 0.1 0.3 0.0 0.2 0.0 0.0 1.2 1.6 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 6.6 0.6 16.8 0.0 0.2 0.1 1.3 0.0 0.1 0.3 0.0 0.3 GPX1 ENSG00000233276 "Glutathione peroxidase 1" P07203 3 49357176-49358353 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3273.8;Kupffer cells: 3971.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1534.3;granulocytes: 1010.7;monocytes: 1337.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011582, HPA044758" Approved Supported Cytosol NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB011582: AB_2112120, HPA044758: AB_2679076" "unprognostic (1.50e-2)" "unprognostic (4.34e-3)" "unprognostic (1.25e-1)" "prognostic favorable (7.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (6.73e-3)" "unprognostic (5.03e-2)" "unprognostic (3.40e-2)" "unprognostic (2.48e-1)" "unprognostic (5.46e-2)" "unprognostic (1.53e-1)" "unprognostic (7.64e-3)" "unprognostic (9.14e-3)" "unprognostic (3.16e-2)" "unprognostic (5.72e-3)" "unprognostic (7.64e-3)" 321.4 200.0 178.3 151.9 186.6 246.7 151.5 190.2 298.9 90.9 247.3 86.9 122.2 82.2 17.8 134.3 86.5 91.1 95.5 173.1 198.9 152.9 281.6 168.3 174.3 234.0 213.0 61.9 74.4 35.2 85.7 121.2 208.3 107.0 42.7 8.3 113.1 53.9 157.1 70.4 113.6 70.4 218.0 195.9 92.9 31.5 217.6 75.3 82.1 61.7 86.6 116.8 94.9 256.3 322.8 189.2 72.6 95.4 113.5 205.9 225.9 217.7 114.7 151.5 80.1 157.8 229.7 0.6 301.6 139.8 181.7 93.2 98.8 660.3 31.6 200.2 271.6 224.8 190.2 397.4 575.6 161.0 594.4 455.9 267.6 292.4 221.5 190.0 341.5 78.6 0.5 179.3 125.9 0.8 51.2 407.0 441.3 147.4 510.5 190.8 93.8 120.3 258.2 385.6 87.7 178.5 249.5 1.5 287.3 75.7 1.5 559.5 546.5 209.7 236.0 385.8 453.6 1.1 127.9 116.3 390.5 436.3 507.8 1010.7 1337.0 707.6 69.8 483.7 100.9 314.2 127.7 83.7 1093.1 276.8 118.4 116.2 136.4 107.4 275.8 1534.3 233.3 1401.2 178.3 186.6 190.2 298.9 173.1 198.9 234.0 213.0 208.3 218.0 217.6 256.3 0.0 109.0 323.5 6.2 148.1 249.7 432.8 985.0 92.2 32.1 0.0 0.0 0.0 220.2 616.7 0.0 10.4 499.9 491.5 229.5 0.0 0.0 300.7 0.0 0.0 227.8 251.3 364.1 12.8 0.0 830.3 131.0 73.4 0.0 480.6 0.0 585.7 888.1 3273.8 1.7 17.9 285.0 386.6 3971.6 965.7 1102.9 134.5 1305.5 273.9 41.2 828.6 63.4 138.0 8.0 7.6 0.0 179.0 67.0 82.4 481.0 349.9 0.0 490.0 14.6 210.4 150.6 151.8 12.7 169.4 112.1 154.1 278.8 112.2 0.0 367.3 517.0 GRB14 ENSG00000115290 "Growth factor receptor bound protein 14" Q14449 2 164492417-164621482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 12.6;tongue: 20.3" "Group enriched" "Detected in many" 4 "Distal tubular cells: 92.0;Granulosa cells: 272.4" "Cancer enhanced" "Detected in many" "liver cancer: 9.5" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.5;HUVEC TERT2: 9.6;RPTEC TERT1: 9.1;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022294, HPA035052, HPA035053" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "CAB022294: , HPA035052: , HPA035053: AB_2674432" "unprognostic (2.60e-1)" "unprognostic (6.34e-2)" "unprognostic (1.74e-2)" "unprognostic (6.75e-2)" "unprognostic (7.47e-2)" "unprognostic (8.33e-5)" "unprognostic (5.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.33e-1)" "unprognostic (5.71e-2)" "unprognostic (8.33e-3)" "unprognostic (2.71e-1)" "unprognostic (1.89e-3)" "unprognostic (7.10e-2)" "unprognostic (5.19e-2)" "unprognostic (9.27e-2)" 0.7 3.0 0.0 0.3 0.4 0.0 0.3 0.0 0.6 0.1 0.1 0.9 0.9 0.2 5.4 1.2 0.1 0.1 2.7 1.3 0.1 6.6 12.6 0.4 0.0 0.3 0.2 2.0 4.7 0.0 0.3 1.7 0.0 0.3 0.3 0.4 0.3 0.3 2.4 0.2 0.2 0.4 0.0 0.2 0.2 2.6 0.3 0.0 0.9 20.3 0.0 0.0 0.1 0.0 0.8 5.5 0.3 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 2.5 0.5 0.0 2.9 0.0 0.9 0.3 0.8 1.2 0.3 0.0 4.1 0.0 0.3 1.3 0.1 0.0 0.0 0.3 0.8 1.8 0.0 1.6 9.6 0.0 0.0 0.0 1.5 2.1 0.0 0.0 1.9 0.2 1.2 0.0 0.0 0.1 9.1 0.4 3.1 0.3 0.0 0.3 0.0 1.1 0.7 0.0 11.8 0.1 1.2 0.0 0.1 0.4 0.1 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.6 1.3 0.1 0.3 0.2 0.0 0.0 0.3 0.0 4.5 0.0 5.4 0.7 0.1 0.1 0.3 0.0 0.0 1.3 1.6 1.4 17.7 22.8 0.0 16.5 0.0 0.2 1.3 0.3 92.0 13.5 1.5 0.6 0.2 3.0 0.0 0.0 24.5 3.3 0.2 2.4 0.0 1.9 0.0 272.4 1.1 40.4 0.0 0.0 6.2 2.6 0.0 1.0 0.3 4.4 9.3 3.2 19.6 1.9 1.0 0.3 0.0 3.5 2.3 4.0 0.0 17.3 0.0 0.8 0.3 14.7 0.0 0.8 13.1 0.8 10.9 0.7 6.4 0.1 0.0 0.1 0.2 30.4 1.6 0.2 GSDMC MLZE ENSG00000147697 "Gasdermin C" Q9BYG8 8 129748196-129786624 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 33.1;lymphoid tissue: 12.8;skin 1: 25.5;vagina: 11.4" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 46.5;Basal squamous epithelial cells: 37.5;Squamous epithelial cells: 29.5;Suprabasal keratinocytes: 53.1" "Cancer enhanced" "Detected in many" "cervical cancer: 11.8;head and neck cancer: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.2;HaCaT: 3.7;hTCEpi: 1.8;HUVEC TERT2: 2.0;TIME: 5.8" "Low region specificity" "Detected in many" "HPA023670, HPA024767, HPA026317" Supported Approved Mitochondria NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Mitochondria "HPA023670: AB_1854006, HPA024767: AB_1854007, HPA026317: AB_1854008" "unprognostic (6.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.61e-3)" "unprognostic (4.23e-2)" "unprognostic (2.11e-2)" "unprognostic (4.22e-3)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (8.28e-2)" "unprognostic (7.51e-2)" "unprognostic (4.92e-3)" "unprognostic (5.71e-2)" "unprognostic (2.93e-3)" "unprognostic (1.87e-2)" "unprognostic (1.88e-1)" "unprognostic (8.66e-2)" "unprognostic (1.90e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.4 0.0 0.0 0.0 0.0 0.1 33.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 5.4 0.0 0.0 25.5 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.4 11.4 0.1 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.0 1.0 0.0 46.5 0.9 7.4 37.5 0.0 1.5 0.9 3.6 0.0 9.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.1 0.0 3.9 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.1 29.5 53.1 0.0 0.1 0.0 0.0 2.8 HBP1 ENSG00000105856 "HMG-box transcription factor 1" O60381 7 107168961-107202522 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 332.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020225, CAB032824" Approved Supported "Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" "CAB032824: AB_2114615, HPA020225: " "unprognostic (9.00e-2)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (4.43e-1)" "unprognostic (4.79e-2)" "unprognostic (7.49e-3)" "unprognostic (1.99e-1)" "unprognostic (2.25e-2)" "unprognostic (3.47e-2)" "unprognostic (2.07e-2)" "unprognostic (2.99e-3)" "unprognostic (1.50e-1)" "prognostic favorable (7.70e-5)" "unprognostic (7.39e-2)" "unprognostic (2.31e-1)" "unprognostic (7.69e-2)" "unprognostic (5.26e-2)" 58.4 49.8 13.2 15.0 18.3 49.0 52.4 17.1 14.8 50.1 15.2 45.9 16.3 53.1 20.0 54.4 40.0 19.9 39.8 13.0 14.7 26.7 37.8 40.1 17.3 19.2 16.1 51.1 34.9 29.0 24.2 24.6 19.2 35.4 17.8 16.5 46.6 22.5 86.4 70.9 34.9 22.1 15.0 34.0 38.0 57.1 14.9 23.6 36.8 39.6 19.9 43.4 51.5 25.7 9.0 10.1 18.8 12.2 38.7 36.1 8.8 15.6 35.1 11.2 19.6 3.6 23.5 8.7 20.4 21.8 23.3 11.4 7.7 9.7 13.9 6.5 7.0 6.0 16.7 6.9 22.1 4.3 17.3 42.3 28.3 10.9 13.3 37.7 37.0 8.8 11.3 21.2 14.5 14.8 7.3 13.6 11.8 12.8 11.5 6.9 13.8 22.4 19.9 11.1 7.3 22.0 18.4 26.7 25.9 25.9 8.3 13.2 35.8 14.7 11.4 22.7 4.7 24.6 31.9 9.0 14.4 9.2 15.3 142.1 59.5 80.0 37.5 61.7 35.8 35.6 39.5 36.5 40.3 34.6 45.2 38.5 146.2 53.8 64.1 20.5 55.6 91.8 13.2 18.3 17.1 14.8 13.0 14.7 19.2 16.1 19.2 15.0 14.9 25.7 67.9 22.4 39.7 37.2 72.9 108.2 77.6 56.2 91.6 29.7 83.1 54.7 22.1 31.5 51.6 33.1 8.4 46.1 95.5 56.1 45.0 50.5 175.9 56.8 45.8 51.8 54.2 59.5 32.6 32.3 26.1 76.8 50.4 93.3 50.7 25.7 35.3 36.8 28.9 42.1 35.2 41.3 85.5 49.8 81.8 332.7 54.0 67.8 74.7 49.6 46.3 33.4 37.0 40.2 91.4 33.7 46.6 57.9 70.2 82.8 55.1 45.3 37.6 29.2 46.0 91.4 70.0 53.0 38.0 55.3 133.0 210.4 94.8 42.6 28.1 89.9 HDX "CXorf43, FLJ30678" ENSG00000165259 "Highly divergent homeobox" Q7Z353 X 84317874-84502479 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 51.1;Inhibitory neurons: 56.7;Oligodendrocyte precursor cells: 45.8;Oligodendrocytes: 26.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047189 Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA047189: AB_10965463" "unprognostic (7.26e-2)" "unprognostic (3.53e-2)" "unprognostic (1.64e-2)" "unprognostic (1.51e-5)" "unprognostic (3.23e-4)" "unprognostic (5.52e-2)" "unprognostic (1.44e-1)" "unprognostic (6.46e-2)" "unprognostic (1.13e-1)" "unprognostic (1.81e-1)" "unprognostic (6.40e-6)" "unprognostic (1.14e-1)" "unprognostic (7.20e-2)" "unprognostic (3.86e-3)" "unprognostic (2.34e-1)" "unprognostic (1.30e-2)" "unprognostic (3.66e-2)" 1.3 1.6 0.6 0.7 0.9 0.0 1.6 2.9 1.6 1.8 0.0 1.3 0.3 1.8 1.5 1.1 1.6 1.3 1.1 0.8 1.3 1.1 1.0 1.0 0.5 1.1 0.6 2.1 0.5 1.2 1.2 0.3 1.0 1.4 1.1 1.8 1.3 1.5 0.4 0.4 0.7 1.7 0.8 1.0 0.7 1.0 0.6 0.4 1.4 0.4 0.6 1.3 1.0 1.3 0.0 1.5 7.5 0.0 4.4 3.9 0.0 2.3 3.2 5.0 4.9 0.3 0.8 0.0 0.4 1.8 6.2 0.3 0.1 0.5 4.3 0.0 0.3 0.0 1.4 0.0 3.6 0.0 0.0 2.2 0.0 3.1 2.2 3.2 5.4 0.0 0.0 0.0 4.9 0.1 0.0 0.0 4.7 0.0 2.2 0.0 5.7 0.0 2.4 1.0 0.2 3.9 0.0 0.1 0.0 2.7 0.4 0.0 6.4 2.5 1.9 0.8 2.2 0.1 0.0 0.0 1.5 0.0 0.9 0.0 2.3 0.0 0.7 3.5 0.1 1.8 0.2 0.2 3.2 0.5 0.6 0.4 0.0 0.9 3.5 0.3 0.1 0.6 0.6 0.9 2.9 1.6 0.8 1.3 1.1 0.6 1.0 0.8 0.6 1.3 7.8 0.0 2.7 19.2 2.8 2.5 23.1 2.8 5.7 9.4 4.8 5.2 1.9 1.5 3.5 5.5 12.5 0.0 2.7 1.7 0.0 7.0 8.7 2.9 7.1 6.7 7.1 0.4 51.1 1.8 0.0 7.7 2.0 6.6 1.3 4.1 1.8 0.7 1.0 6.7 56.7 1.5 0.0 1.9 3.6 2.1 4.1 4.1 0.0 20.6 3.8 4.1 1.0 45.8 26.5 2.9 1.9 3.4 1.2 12.4 0.5 2.9 1.3 5.3 0.0 8.8 7.5 2.4 0.3 3.0 1.7 0.1 1.5 4.7 1.3 19.6 HECW2 "KIAA1301, NEDL2" ENSG00000138411 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2" Q9P2P5 2 196189099-196593684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 331.5;Hepatic stellate cells: 99.2;Inhibitory neurons: 375.4;Oligodendrocyte precursor cells: 143.2;Oligodendrocytes: 460.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.7;non-classical monocyte: 3.7" "Group enriched" "Detected in many" 8 "granulocytes: 4.7;monocytes: 3.7" "Cell line enhanced" "Detected in many" "HDLM-2: 30.1;hTEC/SVTERT24-B: 16.3;HUVEC TERT2: 20.9;SCLC-21H: 31.6;TIME: 26.3;U-138 MG: 21.7" "Low region specificity" "Detected in all" HPA034609 Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034609: AB_10669993" "unprognostic (2.65e-2)" "unprognostic (3.89e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-3)" "unprognostic (2.55e-1)" "unprognostic (4.28e-2)" "unprognostic (7.63e-3)" "unprognostic (1.23e-1)" "unprognostic (2.61e-2)" "unprognostic (7.05e-2)" "unprognostic (4.16e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (5.18e-5)" "unprognostic (8.05e-3)" "unprognostic (5.20e-2)" "unprognostic (1.49e-1)" "unprognostic (4.48e-2)" 4.1 1.5 2.4 1.2 3.5 0.1 1.7 4.4 6.1 2.2 0.0 0.4 0.4 0.8 0.3 3.1 3.5 2.1 8.1 3.3 0.0 1.6 2.7 5.3 2.0 1.1 0.8 0.2 0.6 4.3 1.2 7.4 2.1 0.4 0.4 2.7 0.9 0.5 1.4 0.8 0.5 1.3 0.0 6.0 0.9 3.5 1.7 0.8 3.8 3.5 2.4 1.0 0.6 8.2 0.1 1.4 2.3 0.0 1.4 4.2 1.6 2.7 7.3 2.1 2.6 0.3 0.1 1.4 0.5 13.4 3.3 3.2 0.9 0.1 4.5 30.1 1.6 0.0 2.3 0.2 0.2 0.5 0.3 1.0 1.3 16.3 5.7 4.1 20.9 0.0 0.2 0.1 6.7 1.8 0.0 0.7 2.5 0.2 1.0 0.0 0.5 0.0 0.1 0.0 31.6 2.5 2.0 0.5 0.0 0.4 0.1 0.2 26.3 21.7 1.4 4.6 0.7 0.2 0.0 1.3 5.4 0.1 0.2 0.1 0.3 0.8 0.0 1.1 0.0 0.4 0.0 0.0 0.4 0.5 0.0 0.0 4.7 0.0 3.7 0.0 0.0 0.1 2.4 3.5 4.4 6.1 3.3 0.0 1.1 0.8 2.1 0.0 1.7 8.2 61.2 0.0 12.1 12.7 3.6 2.2 0.3 0.1 3.4 9.5 1.1 0.8 18.7 0.0 0.1 0.0 0.0 0.2 0.7 0.6 0.0 0.1 11.1 0.4 1.6 34.2 2.4 0.0 331.5 0.0 0.3 4.2 0.5 0.3 1.3 4.9 99.2 1.5 0.1 0.0 375.4 0.6 0.0 7.2 3.0 5.3 0.0 1.4 3.6 14.0 1.2 12.0 0.0 143.2 460.7 0.1 0.0 2.6 3.4 0.4 0.0 0.1 1.0 1.1 0.0 1.2 2.2 0.5 6.1 9.2 1.6 0.1 1.4 0.7 0.1 0.6 HES2 bHLHb40 ENSG00000069812 "Hes family bHLH transcription factor 2" Q9Y543 1 6412418-6424670 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 33.7;skin 1: 16.9;vagina: 18.8" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 48.9;Late spermatids: 45.3;Paneth cells: 33.0;Squamous epithelial cells: 58.5;Syncytiotrophoblasts: 99.3" "Cancer enhanced" "Detected in many" "cervical cancer: 17.0;head and neck cancer: 16.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "basophil: 3.0;neutrophil: 1.3" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.0" "Cell line enhanced" "Detected in some" "BEWO: 19.7;HaCaT: 37.6;HBEC3-KT: 32.3;hTCEpi: 18.3;PC-3: 13.4;TIME: 55.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA039462 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA039462: AB_10673533" "unprognostic (1.96e-1)" "unprognostic (7.00e-2)" "unprognostic (1.66e-1)" "unprognostic (6.82e-3)" "unprognostic (1.13e-2)" "unprognostic (1.89e-1)" "unprognostic (2.56e-4)" "unprognostic (4.74e-2)" "unprognostic (7.41e-2)" "unprognostic (3.20e-2)" "unprognostic (5.63e-3)" "unprognostic (1.38e-1)" "unprognostic (7.67e-2)" "unprognostic (5.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.14e-1)" "unprognostic (1.00e-2)" 0.1 0.0 0.2 0.8 0.2 0.4 0.8 0.4 0.4 9.8 0.2 6.1 0.3 0.3 0.6 33.7 2.6 0.1 0.1 0.3 0.2 1.1 0.1 1.1 0.1 0.3 0.2 0.1 0.0 0.3 0.2 6.7 0.4 1.6 4.6 1.2 3.7 0.1 0.1 16.9 1.3 0.3 0.1 0.1 0.1 2.9 0.2 0.3 0.0 0.1 1.7 0.3 18.8 0.7 1.8 0.6 0.0 0.2 0.3 0.1 19.7 0.0 0.0 0.1 0.0 0.5 0.3 0.1 3.5 0.2 0.2 37.6 1.0 32.3 0.0 0.0 0.4 0.3 0.4 0.3 0.3 0.0 0.2 0.1 18.3 0.1 0.7 0.0 9.8 0.0 0.3 0.3 0.1 2.9 0.1 1.6 0.0 2.0 13.4 0.1 0.0 0.2 0.3 0.5 0.2 0.0 1.9 10.3 0.3 1.9 1.4 0.7 55.1 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.1 3.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 1.3 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.4 0.4 0.3 0.2 0.3 0.2 0.4 0.1 0.2 0.7 0.4 9.6 3.9 0.0 0.4 6.5 8.7 10.5 8.0 1.8 2.0 1.5 9.1 0.0 12.7 1.8 4.2 3.6 0.4 17.3 0.0 1.1 19.4 10.3 1.2 1.5 3.0 0.0 0.0 0.0 4.6 1.1 0.0 9.9 1.3 0.2 1.4 0.2 0.9 0.0 0.0 48.9 6.1 0.6 4.8 45.3 0.3 1.2 1.8 0.0 0.1 1.0 1.0 0.0 0.0 0.5 33.0 0.7 0.3 10.9 9.2 6.6 16.8 6.1 0.0 1.4 0.9 5.8 4.8 58.5 19.6 99.3 0.8 0.1 13.1 23.2 HHIP "FLJ20992, HIP" ENSG00000164161 "Hedgehog interacting protein" Q96QV1 4 144646156-144745271 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3;lung: 16.2" "Group enriched" "Detected in many" 5 "Alveolar cells type 2: 175.6;Leydig cells: 136.1;Oligodendrocytes: 413.3;Theca cells: 162.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 322.6;TIME: 376.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012616 Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA012616: AB_1850687" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (7.12e-3)" "unprognostic (8.18e-2)" "unprognostic (2.43e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-1)" "unprognostic (1.95e-2)" "unprognostic (4.20e-1)" "unprognostic (1.90e-2)" "unprognostic (1.89e-1)" "unprognostic (9.66e-3)" "unprognostic (7.13e-3)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" "unprognostic (2.38e-1)" 2.3 2.3 10.4 0.4 25.4 0.8 0.3 10.7 19.6 1.3 0.0 3.2 2.6 1.6 3.8 0.0 0.1 1.1 0.2 17.1 11.0 0.8 6.8 16.2 0.0 20.0 20.2 0.6 2.6 0.0 0.3 0.0 13.6 4.7 3.2 0.9 0.3 2.6 0.4 0.2 3.7 0.1 9.4 0.0 5.9 1.5 18.1 2.7 0.6 1.3 0.0 5.0 0.3 37.3 0.0 0.1 4.9 0.1 0.3 1.9 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 3.0 0.2 0.3 0.0 2.2 0.0 2.0 0.1 0.0 0.1 0.1 0.0 0.0 10.4 7.8 17.2 322.6 29.1 0.1 0.0 4.8 0.0 47.7 0.0 4.4 0.0 2.8 0.4 65.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 376.7 0.4 3.9 0.3 2.5 2.2 0.0 10.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 10.4 25.4 10.7 19.6 17.1 11.0 20.0 20.2 13.6 9.4 18.1 37.3 0.3 12.8 175.6 3.9 0.4 0.0 0.0 0.5 0.0 42.7 0.0 0.0 1.2 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.5 6.0 0.6 0.0 0.0 17.6 0.4 0.0 38.9 0.0 0.4 16.5 0.1 9.3 0.1 0.1 0.0 13.9 0.0 2.0 0.0 0.4 4.5 136.1 1.3 1.8 1.0 0.0 0.3 0.0 8.5 413.3 0.1 0.0 44.0 0.0 0.0 0.0 0.0 4.4 3.3 0.0 1.7 0.9 0.3 0.5 0.0 0.6 0.0 1.0 162.7 0.0 0.0 HIF3A "bHLHe17, IPAS, MOP7, PASD7" ENSG00000124440 "Hypoxia inducible factor 3 subunit alpha" Q9Y2N7 19 46297042-46343433 "Predicted intracellular proteins, Transcription factors" "Angiogenesis, Apoptosis, Stress response, Transcription, Transcription regulation" "Developmental protein, Repressor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 83.5;Astrocytes: 257.9;Endothelial cells: 60.4;Leydig cells: 136.4;Muller glia cells: 79.9;Oligodendrocyte precursor cells: 69.9;Peritubular cells: 103.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.3;HHSteC: 19.1;HSkMC: 16.8;TIME: 16.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041141 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041141: AB_10803997" "unprognostic (9.20e-2)" "unprognostic (2.99e-1)" "unprognostic (5.48e-2)" "prognostic unfavorable (6.90e-9)" "unprognostic (4.12e-2)" "unprognostic (2.35e-2)" "unprognostic (3.57e-3)" "unprognostic (1.30e-1)" "unprognostic (3.32e-2)" "unprognostic (1.38e-2)" "unprognostic (3.76e-2)" "unprognostic (7.07e-2)" "unprognostic (3.41e-4)" "unprognostic (1.55e-2)" "unprognostic (1.61e-1)" "unprognostic (4.45e-4)" "unprognostic (5.98e-2)" 34.2 8.8 24.1 1.1 24.7 0.7 24.2 17.5 25.9 32.5 9.4 55.4 1.1 31.1 4.1 10.8 35.8 2.6 55.9 19.5 17.4 7.3 2.7 32.8 1.2 22.2 22.3 34.2 6.5 0.5 22.6 27.4 18.6 22.3 2.0 10.0 7.5 7.1 10.7 10.8 24.8 3.0 16.8 31.8 37.3 5.4 22.5 0.5 13.0 9.7 0.4 55.0 25.1 17.3 0.0 0.0 1.5 0.2 4.3 9.3 0.4 0.0 0.0 0.0 0.0 2.1 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 19.1 0.1 0.5 16.8 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 2.3 0.0 0.1 16.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.0 1.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.7 0.1 0.4 0.7 0.1 0.0 24.1 24.7 17.5 25.9 19.5 17.4 22.2 22.3 18.6 16.8 22.5 17.3 83.5 3.2 1.8 257.9 0.5 1.1 2.2 0.3 0.6 1.5 1.4 0.9 45.7 17.2 0.7 0.0 0.0 0.2 0.3 0.2 1.9 0.0 1.9 2.4 7.0 60.4 1.2 8.0 0.7 0.0 0.4 13.6 1.1 2.3 0.0 3.1 51.0 0.9 0.6 0.0 3.5 1.2 0.0 1.3 2.1 7.4 136.4 0.7 3.6 33.7 0.0 79.9 0.0 69.9 1.2 0.1 8.0 103.4 0.0 1.6 0.5 0.1 0.0 2.5 6.6 5.5 8.4 1.6 3.6 0.2 2.3 0.5 0.4 0.1 2.1 0.7 HIP1R "FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655" ENSG00000130787 "Huntingtin interacting protein 1 related" O75146 12 122834453-122862961 "Cancer-related genes, Predicted intracellular proteins" Endocytosis Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 103.4" "Cell type enhanced" "Detected in many" "Astrocytes: 134.5;Oligodendrocyte precursor cells: 168.9;Oligodendrocytes: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.3;naive B-cell: 10.6" "Group enriched" "Detected in many" 8 "B-cells: 10.6;granulocytes: 2.9;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017187, HPA038135, HPA038136" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Cytosol" Vesicles "CAB017187: , HPA038135: AB_2675851, HPA038136: AB_2675852" "unprognostic (4.52e-1)" "unprognostic (6.39e-2)" "unprognostic (7.07e-2)" "unprognostic (6.55e-3)" "unprognostic (8.67e-2)" "unprognostic (1.00e-2)" "unprognostic (1.02e-2)" "unprognostic (8.11e-2)" "unprognostic (6.37e-2)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.72e-2)" "prognostic favorable (6.50e-7)" "unprognostic (2.18e-2)" "unprognostic (2.84e-1)" "unprognostic (2.54e-3)" "prognostic favorable (7.26e-4)" 18.5 24.0 68.6 10.4 95.5 13.3 22.6 78.8 80.3 16.0 33.5 16.3 31.8 9.0 3.8 18.0 9.0 7.7 18.9 68.0 67.8 50.2 25.6 15.4 17.5 87.3 83.8 5.6 50.2 8.9 42.0 4.7 75.6 21.0 4.9 5.5 58.7 10.5 7.2 51.7 36.0 2.2 65.3 20.9 66.7 8.5 85.7 12.6 21.5 4.4 11.7 11.4 19.7 103.4 38.1 10.8 8.0 33.1 2.3 6.1 39.2 5.9 9.5 5.9 4.6 16.8 11.1 36.0 19.0 4.3 8.9 32.4 9.7 21.4 0.5 5.8 14.0 0.8 13.8 17.8 7.1 2.8 24.5 3.8 14.9 8.0 13.4 8.1 40.5 16.5 9.6 2.0 3.4 54.4 17.4 8.8 7.4 32.8 12.8 9.0 10.2 12.5 19.6 45.4 8.1 17.9 7.1 18.0 9.5 4.3 36.6 1.5 32.8 3.7 27.5 11.7 5.7 24.8 14.2 21.8 6.0 6.0 3.1 0.0 0.0 2.9 2.7 0.0 1.5 9.3 1.7 2.1 0.0 10.6 3.0 1.9 0.2 0.7 0.0 0.0 0.4 2.0 68.6 95.5 78.8 80.3 68.0 67.8 87.3 83.8 75.6 65.3 85.7 103.4 57.0 0.0 13.4 134.5 38.0 13.3 16.8 8.4 6.8 16.4 21.2 18.2 4.2 60.1 11.1 60.7 29.2 3.7 18.2 28.4 0.0 40.1 3.1 21.9 4.7 18.2 7.8 1.3 11.2 28.7 13.1 2.3 80.5 37.5 5.7 25.3 19.2 24.4 0.6 18.5 9.7 29.9 22.4 1.2 4.2 2.9 1.5 2.2 10.6 9.4 0.1 12.5 7.2 168.9 117.8 22.7 25.3 1.2 17.2 20.2 47.5 17.9 14.2 16.6 0.0 2.5 4.1 6.5 13.3 11.5 21.0 1.9 15.0 1.3 23.9 28.4 HMOX2 HO-2 ENSG00000103415 "Heme oxygenase 2" P30519 16 4474690-4510347 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 515.3;Late spermatids: 2001.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025464, HPA040611" Supported Approved Vesicles,Cytosol NA NA 12000 "Cluster 20: T-cells - T-cell receptor" "Cluster 43: Testis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" "CAB025464: , HPA040611: AB_10961034" "unprognostic (3.33e-1)" "unprognostic (3.58e-2)" "unprognostic (1.11e-1)" "prognostic favorable (7.91e-4)" "unprognostic (2.74e-1)" "unprognostic (4.27e-2)" "unprognostic (6.23e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (3.60e-1)" "unprognostic (7.74e-3)" "unprognostic (9.87e-2)" "prognostic favorable (8.98e-6)" "unprognostic (3.51e-2)" "unprognostic (4.14e-2)" "unprognostic (1.65e-2)" "unprognostic (2.64e-1)" 63.0 51.3 43.7 23.2 51.9 18.3 55.7 56.9 55.2 47.1 36.2 41.0 34.8 35.8 22.5 84.5 35.9 26.9 149.9 47.7 50.0 71.2 109.5 46.6 33.2 55.8 49.2 25.6 39.7 38.6 43.8 17.9 57.1 34.5 25.1 22.5 44.1 14.1 37.9 44.4 42.6 22.7 44.7 67.8 100.2 152.2 54.3 24.3 41.9 32.3 36.3 33.2 49.0 53.5 82.9 38.2 20.5 45.6 65.8 31.5 33.8 53.9 26.5 48.3 43.7 48.3 55.5 36.9 64.0 55.7 34.6 51.5 75.4 126.9 48.4 51.5 48.4 27.5 35.2 63.3 43.7 56.8 44.4 48.7 41.7 55.7 37.6 37.9 83.7 46.9 44.7 18.1 44.5 114.3 48.7 58.4 34.2 81.1 35.7 54.3 33.7 84.4 72.3 51.8 34.4 19.4 43.1 95.1 66.4 33.9 58.2 36.3 91.7 25.7 39.9 120.3 30.1 24.3 30.0 78.0 16.5 52.5 35.2 87.6 37.1 252.6 166.3 46.5 142.1 69.8 153.8 168.5 73.6 66.8 145.5 151.6 125.1 99.0 35.7 39.2 155.4 142.3 43.7 51.9 56.9 55.2 47.7 50.0 55.8 49.2 57.1 44.7 54.3 53.5 33.8 35.3 41.5 7.8 37.2 54.8 35.7 73.5 19.4 29.3 26.4 29.1 70.6 32.9 54.5 36.8 20.9 75.3 59.8 70.7 129.1 79.7 515.3 38.6 30.9 53.4 31.8 14.3 23.0 90.7 69.6 39.4 89.7 53.3 19.7 38.8 75.0 93.0 67.2 28.6 21.6 37.6 85.5 23.9 52.9 2001.6 45.4 30.6 62.2 5.6 29.3 53.9 141.1 9.5 32.9 114.9 70.7 56.1 47.1 37.7 110.8 239.3 39.9 27.8 72.3 14.6 58.0 199.7 149.8 28.2 51.6 38.4 88.3 47.4 48.9 28.7 HOOK3 HK3 ENSG00000168172 "Hook microtubule tethering protein 3" Q86VS8 8 42896946-43030535 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024756 Approved Supported "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA024756: AB_1850913" "unprognostic (1.84e-2)" "unprognostic (1.61e-1)" "unprognostic (2.73e-1)" "unprognostic (8.61e-3)" "unprognostic (6.05e-2)" "unprognostic (1.77e-3)" "unprognostic (2.36e-1)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.13e-1)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.63e-1)" "unprognostic (3.78e-1)" "unprognostic (2.55e-1)" "unprognostic (7.12e-2)" 9.8 6.2 3.1 7.4 8.7 11.1 8.9 11.9 8.9 8.2 1.5 7.5 7.5 8.3 8.2 10.6 7.0 14.4 4.6 4.0 11.1 6.6 7.3 8.0 6.6 7.6 4.9 6.1 7.6 7.2 4.1 8.6 7.3 12.4 7.7 8.8 9.6 7.1 10.6 8.1 8.9 6.7 4.4 6.6 9.5 11.4 4.9 6.4 21.7 8.2 7.4 9.3 6.0 15.5 11.2 10.9 26.2 14.2 19.0 16.7 10.1 14.0 11.6 11.5 10.7 14.5 12.8 13.9 13.9 18.8 10.9 6.4 22.1 9.5 18.5 9.5 6.4 26.3 9.2 10.2 10.6 2.8 14.9 13.7 6.6 15.4 13.2 15.9 16.7 9.7 14.7 15.9 14.0 2.7 21.7 5.2 9.5 8.8 3.3 12.6 27.3 3.5 8.6 16.5 6.7 10.6 15.9 6.7 7.4 11.4 12.2 9.4 30.2 17.1 13.2 20.9 9.0 15.6 18.6 18.1 14.5 9.9 25.8 9.4 2.0 2.0 1.2 2.0 0.4 0.9 1.1 0.9 2.4 0.9 0.6 0.8 2.2 1.2 1.9 1.4 0.8 1.1 3.1 8.7 11.9 8.9 4.0 11.1 7.6 4.9 7.3 4.4 4.9 15.5 75.3 93.0 60.6 90.1 43.2 68.3 36.2 28.7 43.3 40.1 29.4 22.4 48.2 44.3 43.6 25.8 33.3 43.6 40.6 26.1 27.4 47.1 120.3 60.0 84.0 65.2 65.4 34.5 102.1 32.8 25.9 65.8 33.1 93.8 53.8 37.9 60.3 36.4 38.0 75.7 107.6 26.9 20.3 79.4 96.4 36.3 44.7 82.8 55.2 78.7 118.6 36.3 37.0 119.1 157.8 59.7 27.6 53.8 43.6 43.5 37.3 21.4 35.2 32.2 65.7 63.4 74.6 28.0 21.5 39.8 74.7 113.7 40.9 42.6 16.2 71.1 HOPX "HOP, LAGY, NECC1, OB1, SMAP31" ENSG00000171476 "HOP homeobox" Q9BPY8 4 56647988-56681899 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 716.7;skin 1: 1439.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 750.0;Alveolar cells type 2: 569.2;Basal keratinocytes: 414.6;dendritic cells: 345.3;NK-cells: 1150.4;Suprabasal keratinocytes: 377.2;Syncytiotrophoblasts: 321.8" "Cancer enhanced" "Detected in many" "glioma: 43.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 518.2;NK-cell: 781.6" "Group enriched" "Detected in all" 15 "NK-cells: 781.6;T-cells: 518.2" "Cell line enhanced" "Detected in many" "HDLM-2: 31.2;HUVEC TERT2: 66.9;RT4: 50.5;TIME: 76.2;U-266/70: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018632, HPA030180" Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear bodies" Cytosol "CAB018632: AB_2120833, HPA030180: AB_10603770" "unprognostic (2.32e-1)" "unprognostic (1.81e-2)" "unprognostic (8.03e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (1.78e-2)" "unprognostic (2.88e-1)" "unprognostic (7.79e-2)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (9.30e-5)" "unprognostic (3.40e-2)" "unprognostic (1.51e-1)" "unprognostic (7.10e-2)" "unprognostic (5.33e-2)" 9.5 33.7 212.8 27.7 235.6 12.1 112.2 215.4 322.0 250.1 239.2 30.5 17.2 19.1 541.4 716.7 10.5 35.1 48.8 237.4 212.0 24.0 2.9 372.8 18.4 237.6 211.6 9.4 5.3 13.3 11.7 59.6 218.5 26.9 7.0 22.1 172.0 64.7 19.2 1439.9 11.3 115.6 238.8 11.9 33.9 45.3 215.0 15.8 224.5 31.8 190.4 34.1 368.6 234.2 0.0 0.0 0.0 0.0 5.0 15.7 5.9 0.0 0.0 1.4 1.0 0.0 0.0 12.6 0.7 0.3 2.3 2.2 1.4 0.0 1.9 31.2 0.2 0.1 0.0 0.0 2.0 0.0 0.1 2.6 11.9 3.6 0.0 3.4 66.9 0.0 0.0 0.5 3.2 0.5 0.1 1.0 0.1 3.6 0.0 0.0 0.0 0.3 0.0 50.5 1.0 0.6 0.0 0.0 0.0 4.6 0.0 0.0 76.2 0.0 0.2 0.5 0.1 26.0 0.1 0.1 3.2 0.0 0.0 5.7 1.1 2.0 518.2 3.5 282.0 43.4 123.6 227.6 2.6 36.5 20.9 150.8 11.2 781.6 4.5 3.6 9.1 365.6 212.8 235.6 215.4 322.0 237.4 212.0 237.6 211.6 218.5 238.8 215.0 234.2 14.5 750.0 569.2 38.2 23.3 414.6 42.2 8.7 59.7 3.5 3.4 3.0 14.8 2.8 125.6 1.8 0.0 2.3 345.3 0.8 1.9 0.4 33.3 2.8 4.0 28.7 8.4 30.5 62.2 0.2 5.5 16.7 5.6 5.2 10.1 99.5 5.3 1.2 4.0 0.0 7.9 11.1 4.1 11.4 30.9 45.9 3.1 7.9 35.6 14.0 41.4 166.4 1150.4 7.1 6.7 1.7 0.0 3.0 9.6 31.3 1.2 0.6 12.5 5.6 32.9 3.7 104.8 3.3 15.3 31.6 377.2 321.8 219.9 0.1 1.4 28.8 HSPA12B "C20orf60, dJ1009E24.2" ENSG00000132622 "Heat shock protein family A (Hsp70) member 12B" Q96MM6 20 3732685-3753111 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 65.0;Endothelial cells: 50.1;Hepatic stellate cells: 16.1;Late spermatids: 16.8;Microglial cells: 15.0;Peritubular cells: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 4.9;EFO-21: 4.9;HUVEC TERT2: 9.5;TIME: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013659, HPA015639" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA013659: AB_1234541, HPA015639: AB_1851192" "unprognostic (1.00e-1)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (6.99e-2)" "unprognostic (4.53e-2)" "unprognostic (2.09e-1)" "unprognostic (1.21e-1)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.07e-2)" "unprognostic (6.45e-2)" "unprognostic (8.74e-2)" "unprognostic (2.61e-2)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (4.05e-1)" "unprognostic (1.66e-2)" 23.1 4.1 9.3 3.0 8.9 1.3 23.0 6.6 7.8 15.0 4.2 6.6 1.8 12.5 1.2 4.2 10.3 4.7 29.3 6.6 7.0 11.8 1.7 20.6 1.7 8.2 7.9 8.2 2.6 1.5 2.9 11.3 8.4 4.9 1.2 0.4 5.4 1.9 12.3 7.7 6.1 4.0 6.8 25.3 5.1 5.2 10.4 0.7 9.2 10.2 0.9 10.2 10.2 6.0 0.5 1.7 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.2 4.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 2.6 0.1 0.1 0.0 0.1 0.0 0.1 0.0 1.4 9.5 0.4 0.3 0.2 0.0 1.0 0.4 0.9 1.0 0.0 0.8 1.8 0.2 0.5 0.0 0.0 0.9 0.7 0.3 0.2 0.1 0.1 0.2 0.5 5.3 0.1 2.2 0.7 0.4 0.4 0.3 0.5 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 9.3 8.9 6.6 7.8 6.6 7.0 8.2 7.9 8.4 6.8 10.4 6.0 65.0 0.0 0.0 0.3 0.4 1.9 0.1 0.0 0.0 0.5 0.7 0.3 5.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 9.8 0.2 3.2 50.1 0.0 0.0 0.5 0.0 0.2 10.5 0.0 0.1 0.0 0.1 16.1 0.3 0.5 0.0 0.4 0.0 0.0 1.4 2.5 16.8 7.5 0.2 0.0 15.0 0.0 3.1 0.0 0.0 0.3 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.2 2.0 3.5 1.7 0.3 1.1 0.4 0.3 0.7 0.0 0.2 HSPG2 "perlecan, PRCAN, SJS1" ENSG00000142798 "Heparan sulfate proteoglycan 2" P98160 1 21822244-21937310 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 366.8;Endothelial cells: 322.9;Granulosa cells: 776.0;Hepatic stellate cells: 600.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 293.0;HUVEC TERT2: 620.8;TIME: 504.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009820, HPA018892, CAB020718, HPA072690" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 1400000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB009820: AB_2119229, CAB020718: , HPA018892: AB_1850597, HPA072690: " "unprognostic (1.61e-1)" "unprognostic (1.57e-2)" "unprognostic (4.93e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (8.56e-2)" "unprognostic (4.55e-1)" "unprognostic (1.90e-2)" "unprognostic (9.35e-2)" "unprognostic (2.19e-3)" "unprognostic (5.82e-2)" "unprognostic (2.83e-1)" "unprognostic (1.21e-3)" "unprognostic (1.17e-2)" "unprognostic (4.86e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (2.82e-4)" 140.7 54.7 3.8 36.1 5.2 1.7 96.2 3.7 4.8 65.9 18.8 153.1 18.3 151.9 6.6 44.1 85.0 53.4 156.6 3.6 2.9 37.6 10.6 49.0 14.2 5.6 4.6 31.3 31.7 13.1 11.8 30.3 5.7 60.3 8.6 0.3 45.0 56.5 65.1 41.0 54.9 96.2 4.0 37.4 76.1 9.0 7.6 6.7 69.1 40.8 3.5 110.2 59.7 4.7 44.0 40.7 13.8 45.9 131.0 99.4 51.5 70.2 17.8 21.1 18.7 50.5 86.7 3.3 293.0 112.9 0.8 26.9 3.1 31.9 5.4 0.6 4.3 15.7 46.0 35.7 27.0 0.0 4.1 61.6 9.4 19.9 6.0 28.1 620.8 0.3 21.4 5.7 32.4 11.8 0.0 20.0 11.7 19.6 17.9 6.3 87.8 6.1 35.1 6.5 1.3 4.1 51.4 20.0 28.7 14.0 8.1 7.2 504.3 41.1 51.8 29.7 2.3 0.5 7.3 2.6 9.7 0.1 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 5.2 3.7 4.8 3.6 2.9 5.6 4.6 5.7 4.0 7.6 4.7 366.8 70.5 28.6 3.6 3.9 26.4 13.5 81.1 21.1 0.6 6.2 21.5 5.8 38.6 30.3 92.0 0.0 11.0 3.4 52.9 0.0 76.1 1.4 24.2 47.7 322.9 2.4 22.9 0.8 25.0 89.0 141.3 62.2 39.8 23.4 776.0 600.4 6.6 6.8 3.3 0.8 12.6 16.2 22.1 19.2 5.8 75.2 4.6 60.5 15.9 1.8 1.6 0.0 2.5 4.3 87.5 29.9 69.2 4.6 19.3 19.2 0.9 28.7 0.6 32.9 82.5 69.8 0.3 4.8 10.0 17.8 9.3 5.0 83.3 20.1 11.8 HTR1B "5-HT1B, 5-HT1DB, HTR1D2, S12" ENSG00000135312 "5-hydroxytryptamine receptor 1B" P28222 6 77460924-77463491 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 9.6;placenta: 6.7;stomach 1: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "pancreatic cancer: 0.7;stomach cancer: 0.8;testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "HUVEC TERT2: 79.4;TIME: 35.1" "Region enriched" "Detected in all" 4 "basal ganglia: 38.6" "Region enhanced" "Detected in many" "basal ganglia: 11.7" HPA028808 Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Plasma membrane" "Endoplasmic reticulum" "HPA028808: AB_2672782" "unprognostic (3.86e-2)" "unprognostic (3.56e-1)" "unprognostic (7.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.11e-1)" "unprognostic (8.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-3)" "unprognostic (3.08e-2)" "unprognostic (2.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" 0.8 0.6 2.1 0.4 6.0 0.0 0.2 0.0 3.8 0.8 0.0 0.1 0.1 0.5 0.0 0.0 0.5 0.5 0.0 1.2 2.1 0.5 0.0 0.4 0.0 0.6 4.3 0.3 0.1 0.0 0.2 6.7 1.2 0.2 0.1 0.3 0.2 0.5 0.1 0.2 0.1 0.1 0.1 0.0 5.0 0.5 9.6 0.0 0.2 0.3 0.0 1.3 0.5 1.4 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.4 3.5 1.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.2 0.6 2.2 1.4 79.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 6.0 0.0 3.8 1.2 2.1 0.6 4.3 1.2 0.1 9.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HTR1D "5-HT1D, HT1DA, HTRL, RDC4" ENSG00000179546 "5-hydroxytryptamine receptor 1D" P28221 1 23191895-23194729 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 12.4;intestine: 9.4" "Group enriched" "Detected in some" 7 "Cholangiocytes: 5.7;Proximal enterocytes: 6.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 12.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 10.5;hTERT-RPE1: 9.8;OE19: 14.3;TIME: 26.4;U-2 OS: 8.4" NA NA "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.73e-2)" "unprognostic (8.69e-3)" "unprognostic (8.86e-3)" "unprognostic (2.03e-1)" "unprognostic (2.65e-2)" "unprognostic (5.97e-4)" "prognostic unfavorable (1.86e-4)" "unprognostic (3.87e-3)" "unprognostic (8.88e-2)" "unprognostic (4.00e-2)" "prognostic unfavorable (5.30e-4)" "unprognostic (3.17e-2)" "unprognostic (3.28e-6)" "unprognostic (9.14e-2)" "unprognostic (2.27e-1)" "unprognostic (2.45e-1)" "unprognostic (8.02e-3)" 0.0 0.0 1.9 0.2 5.7 0.2 0.1 0.3 3.8 0.0 0.1 0.2 9.4 0.1 0.0 0.0 0.5 1.6 0.0 1.4 1.3 0.0 0.0 0.1 0.0 0.6 12.4 0.0 0.2 0.1 0.1 0.2 1.7 0.1 0.2 0.1 0.0 0.1 0.1 0.1 8.2 0.1 2.0 0.1 0.1 0.2 4.4 0.0 0.1 0.0 0.1 0.1 0.0 0.7 3.2 10.5 0.1 0.0 0.0 0.2 0.9 0.0 0.8 0.3 0.4 0.7 7.5 0.0 3.0 0.4 5.2 2.2 2.1 0.0 0.5 0.0 0.9 0.0 6.0 0.1 0.4 0.0 0.0 0.1 0.2 1.3 0.4 9.8 6.1 0.1 0.1 0.0 0.2 1.3 0.0 0.0 2.5 14.3 0.1 0.0 0.0 0.0 0.2 0.0 2.5 0.0 7.0 0.4 0.1 0.8 0.1 0.0 26.4 0.0 8.4 0.1 2.5 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 1.9 5.7 0.3 3.8 1.4 1.3 0.6 12.4 1.7 2.0 4.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 5.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.3 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.7 HYAL2 "LuCa-2, LUCA2" ENSG00000068001 "Hyaluronidase 2" Q12891 3 50317790-50322782 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 282.8" "Group enriched" "Detected in many" 5 "Adipocytes: 497.6;Endothelial cells: 216.3;Hepatic stellate cells: 253.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "HUVEC TERT2: 363.3;TIME: 502.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036436 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA036436: AB_10670104" "unprognostic (9.97e-3)" "unprognostic (2.60e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-3)" "unprognostic (3.44e-1)" "unprognostic (7.41e-2)" "unprognostic (7.93e-2)" "unprognostic (4.70e-1)" "unprognostic (1.44e-1)" "unprognostic (6.76e-2)" "unprognostic (2.36e-1)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (7.36e-2)" "unprognostic (2.72e-1)" "unprognostic (7.02e-3)" "unprognostic (5.62e-2)" 97.4 62.6 24.7 29.1 23.0 3.1 93.9 24.9 28.3 51.6 24.3 34.0 17.9 66.1 10.3 39.7 55.6 47.5 92.2 22.3 24.8 85.1 32.2 186.8 40.0 26.0 24.9 29.1 27.9 25.7 41.6 87.4 27.5 37.2 11.5 3.3 37.5 22.0 30.9 37.1 38.7 37.4 27.1 282.8 38.6 22.0 28.1 9.5 80.9 35.7 14.6 47.0 45.8 24.9 26.8 38.5 63.0 64.1 38.2 32.9 39.6 29.8 41.2 42.0 32.6 44.6 77.3 7.0 102.4 43.6 82.5 27.4 24.6 58.7 12.0 14.2 19.6 9.7 34.9 69.2 33.0 8.1 24.4 51.9 48.8 42.1 13.8 38.1 363.3 18.2 17.6 8.0 35.4 37.0 17.7 16.6 72.0 23.2 55.7 15.5 12.4 26.1 52.4 24.2 16.6 53.3 30.4 31.2 31.8 21.2 34.4 20.3 502.9 50.0 49.7 33.5 47.5 13.9 24.1 21.6 29.4 25.5 73.0 0.0 9.5 10.7 1.4 14.1 3.0 1.1 1.3 3.8 5.3 1.5 0.4 0.7 9.2 2.8 13.6 4.0 1.9 3.3 24.7 23.0 24.9 28.3 22.3 24.8 26.0 24.9 27.5 27.1 28.1 24.9 497.6 19.2 9.9 5.2 3.6 13.0 28.6 45.2 11.4 7.8 17.6 16.6 7.3 32.9 30.9 33.1 6.2 33.6 4.1 13.5 11.7 53.0 4.7 8.5 19.8 216.3 7.3 10.1 1.6 38.7 38.4 26.6 16.8 13.8 0.0 31.5 253.1 9.1 46.2 8.4 1.9 13.0 42.7 12.6 9.3 5.0 24.5 9.4 17.8 15.9 7.6 19.7 5.2 4.0 3.4 45.6 13.5 22.2 4.2 45.3 16.1 11.8 11.0 6.1 39.5 11.2 26.0 11.2 56.0 24.9 12.6 32.7 4.1 50.0 16.6 33.3 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 IGF2BP3 "CT98, IMP-3, IMP3" ENSG00000136231 "Insulin like growth factor 2 mRNA binding protein 3" O00425 7 23310209-23470491 "Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.3;placenta: 28.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 84.8;Early spermatids: 40.8;Extravillous trophoblasts: 93.4;Hofbauer cells: 38.5;Late spermatids: 24.1;Syncytiotrophoblasts: 78.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 170.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002037, HPA076951" Enhanced Supported Cytosol NA NA 27000 "Cluster 24: B-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA002037: AB_1851483, HPA076951: " "unprognostic (5.72e-2)" "unprognostic (3.12e-1)" "unprognostic (7.25e-2)" "unprognostic (3.56e-3)" "unprognostic (1.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.64e-3)" "unprognostic (3.18e-2)" "unprognostic (2.60e-3)" "unprognostic (3.67e-1)" "unprognostic (1.02e-5)" "unprognostic (8.76e-2)" "unprognostic (0.00e+0)" "unprognostic (1.43e-1)" "unprognostic (7.95e-2)" "unprognostic (2.87e-4)" "unprognostic (7.51e-3)" 0.3 0.0 0.6 0.8 0.3 0.6 0.1 0.2 0.4 0.1 0.0 0.1 0.0 0.0 0.8 2.1 0.9 0.2 0.0 0.3 0.0 0.0 0.5 0.5 4.2 0.0 0.0 0.0 0.6 0.3 0.0 28.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 5.1 0.3 1.6 0.8 0.1 7.3 0.2 0.2 0.1 48.7 14.0 104.5 31.0 16.2 42.8 63.7 8.1 35.7 19.6 24.2 45.0 37.4 36.4 42.1 21.3 86.4 31.2 45.8 35.2 34.2 5.9 18.3 19.3 38.1 37.9 50.3 35.5 13.1 44.1 24.2 15.0 6.3 114.7 170.0 20.0 89.5 0.2 47.8 0.0 21.6 23.5 83.0 36.6 43.3 33.2 34.8 47.1 38.4 4.2 27.4 59.6 4.8 0.3 38.9 118.3 0.0 6.6 68.9 18.6 1.2 40.6 21.0 0.0 15.8 56.7 73.8 38.6 72.8 0.0 0.4 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 1.0 2.8 0.3 0.7 0.3 0.0 0.5 0.0 0.0 0.5 0.0 0.3 0.0 0.0 84.8 1.4 0.1 0.0 1.2 40.8 5.4 0.2 1.7 0.0 0.0 2.0 0.2 93.4 3.5 0.0 1.5 3.8 0.1 1.1 0.2 38.5 1.7 12.9 0.0 0.0 0.8 0.6 24.1 2.1 11.3 3.6 5.6 2.9 0.2 2.1 1.5 1.8 1.0 0.0 0.0 2.1 0.2 0.0 0.1 2.6 1.6 0.0 0.4 7.7 6.8 3.5 0.7 0.4 78.5 0.3 0.0 0.0 0.6 IGHJ3 ENSG00000242887 "Immunoglobulin heavy joining 3" 14 105864587-105864635 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 36.4;intestine: 57.9;pancreas: 61.6" "Cell type enriched" "Detected in single" 48 "Plasma cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 9.0;naive B-cell: 29.1" "Group enriched" "Detected in many" 7 "B-cells: 29.1;granulocytes: 9.0" "Cell line enhanced" "Detected in some" "Daudi: 1.5;RPMI-8226: 6.1;TIME: 8.0;U-251 MG: 2.6" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.67e-4)" "unprognostic (8.67e-3)" "unprognostic (1.12e-1)" "unprognostic (2.42e-2)" "prognostic favorable (3.86e-5)" "unprognostic (3.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.82e-1)" "unprognostic (4.22e-2)" "unprognostic (2.03e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (8.47e-2)" "unprognostic (2.54e-1)" "unprognostic (9.62e-2)" "unprognostic (1.30e-1)" 16.2 3.0 0.6 0.0 0.9 0.0 0.0 0.2 2.5 1.9 0.5 0.0 0.0 0.0 0.0 36.4 0.7 9.1 0.0 0.6 0.9 0.9 10.2 17.3 0.0 1.5 0.4 11.3 61.6 0.0 0.0 0.0 1.7 7.5 57.9 0.1 0.0 4.3 0.0 2.4 0.0 0.0 1.4 0.0 0.0 0.3 0.7 0.0 2.4 0.0 0.0 5.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.2 0.0 0.9 0.0 0.7 1.1 2.6 29.1 1.5 1.2 0.0 0.4 0.7 0.0 1.2 0.0 0.6 0.9 0.2 2.5 0.6 0.9 1.5 0.4 1.7 1.4 0.7 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 209.7;lymphoid tissue: 398.1;salivary gland: 213.2" "Cell type enriched" "Detected in some" 86 "Plasma cells: 3885.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.1;NB-4: 2.1;NTERA-2: 1.2;RH-30: 2.3;TIME: 1.9" "Immunoglobulin genes" NA NA 37000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.30e-4)" "unprognostic (1.21e-2)" "unprognostic (7.19e-3)" "unprognostic (1.51e-2)" "unprognostic (9.16e-3)" "prognostic favorable (9.34e-4)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (4.05e-1)" "prognostic unfavorable (9.31e-8)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" 18.1 2.7 0.3 0.0 0.3 0.0 24.8 0.2 1.1 16.8 0.3 209.7 0.0 7.1 0.9 17.4 30.9 0.0 2.0 0.2 0.3 15.4 10.7 55.3 0.0 0.4 0.3 2.9 16.2 2.3 1.3 0.6 0.4 7.2 0.0 0.0 213.2 0.3 0.4 4.3 111.3 0.8 0.4 398.1 83.0 0.4 0.3 0.0 25.6 0.0 0.0 27.7 10.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 2.1 1.2 0.0 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.2 1.1 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 1.0 21.4 0.0 0.0 0.1 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3885.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGLV10-54 ENSG00000211642 "Immunoglobulin lambda variable 10-54" A0A075B6I4 22 22038643-22215270 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 121.9;intestine: 324.6;lymphoid tissue: 329.7;salivary gland: 253.6;stomach 1: 194.5" "Cell type enriched" "Detected in some" 17 "Plasma cells: 358.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 2.2" "Group enriched" "Detected in some" 32 "memory B-cell: 60.0;naive B-cell: 35.2" "Lineage enriched" "Detected in many" 41 "B-cells: 60.0" "Cell line enhanced" "Detected in single" "TIME: 2.3" "Immunoglobulin genes" NA NA 54000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.35e-5)" "unprognostic (2.65e-2)" "unprognostic (9.06e-2)" "unprognostic (8.71e-3)" "unprognostic (1.29e-1)" "prognostic favorable (8.30e-5)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" "unprognostic (5.62e-1)" "unprognostic (1.18e-1)" "unprognostic (3.22e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (3.33e-1)" "unprognostic (5.57e-2)" "unprognostic (5.17e-2)" "unprognostic (3.86e-1)" 3.6 1.9 0.1 96.4 0.3 33.8 121.9 0.1 2.2 2.0 0.8 324.6 294.8 1.5 0.0 22.5 24.3 21.9 12.0 0.1 0.3 2.5 7.0 22.3 64.7 1.4 0.1 2.6 11.6 0.0 0.4 0.4 0.2 6.4 155.1 0.0 253.6 2.3 0.1 1.0 138.9 12.7 0.2 155.3 194.5 0.4 0.1 22.9 2.5 0.0 329.7 21.8 4.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 60.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.1 0.3 0.1 2.2 0.1 0.3 1.4 0.1 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IL18BP IL18BPa ENSG00000137496 "Interleukin 18 binding protein" O95998 11 71998613-72005715 "Disease related genes, Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "Adipocytes: 14.0;Exocrine glandular cells: 13.6;Kupffer cells: 14.2;Langerhans cells: 12.9;Macrophages: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025980, HPA041061" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 3070000 16000000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "CAB025980: , HPA041061: AB_2677280" "unprognostic (2.66e-3)" "unprognostic (2.04e-3)" "unprognostic (9.14e-3)" "unprognostic (1.70e-2)" "unprognostic (5.58e-3)" "unprognostic (7.75e-2)" "unprognostic (1.41e-1)" "unprognostic (6.20e-2)" "unprognostic (1.19e-2)" "unprognostic (1.75e-3)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.93e-6)" "unprognostic (1.19e-1)" "unprognostic (4.14e-2)" "unprognostic (6.76e-2)" "unprognostic (1.93e-2)" 14.4 18.4 6.0 25.0 6.3 7.9 13.6 7.1 9.1 12.5 4.9 12.7 8.3 10.4 3.5 6.4 10.1 8.1 10.9 5.8 8.3 24.9 15.0 31.1 26.2 8.7 7.8 11.1 8.4 2.5 10.7 17.1 9.0 16.5 11.0 3.8 8.9 4.2 5.0 7.4 17.2 13.5 6.1 49.2 10.2 6.1 8.5 6.5 12.6 2.4 11.9 12.2 8.5 7.3 1.7 2.3 5.1 2.9 1.0 1.6 5.9 3.3 1.8 3.0 4.0 11.7 2.4 1.2 2.2 1.3 3.4 4.0 2.5 2.4 2.0 2.5 3.8 4.5 7.6 3.7 1.3 2.4 12.3 2.4 2.3 2.4 1.2 3.5 6.3 7.9 7.4 2.0 1.8 3.2 3.8 5.7 3.6 1.9 2.2 6.1 5.4 1.9 2.1 4.4 2.8 5.3 3.0 4.2 3.7 4.8 3.6 2.7 13.6 4.2 3.5 5.1 1.9 3.3 1.8 2.1 1.7 11.5 2.3 7.0 20.2 56.1 52.5 72.9 23.9 31.9 27.5 31.6 36.9 20.2 22.5 32.5 8.6 5.2 60.9 53.7 15.1 39.8 6.0 6.3 7.1 9.1 5.8 8.3 8.7 7.8 9.0 6.1 8.5 7.3 14.0 6.4 3.3 0.7 8.0 2.0 0.4 0.7 0.0 3.3 2.1 1.9 1.8 1.5 1.0 0.0 10.4 1.0 7.2 0.5 0.0 3.0 0.0 1.1 1.9 11.1 0.0 0.8 0.7 13.6 1.4 3.4 1.1 1.8 7.6 2.2 10.4 0.5 11.2 3.3 0.5 0.8 0.0 14.2 12.9 0.0 0.9 15.4 0.0 1.0 4.6 1.1 7.2 0.5 0.0 5.4 0.2 0.7 2.3 1.0 1.1 1.9 1.8 3.7 0.0 1.8 1.6 0.7 0.5 0.6 2.0 0.8 6.4 1.6 0.8 0.2 IL6ST "CD130, GP130, sGP130" ENSG00000134352 "Interleukin 6 signal transducer" P40189 5 55935095-55995022 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 580.3;Hepatic stellate cells: 808.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 16.7" "Lineage enriched" "Detected in many" 4 "T-cells: 16.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 151.3;BJ hTERT+: 175.2;HHSteC: 155.1;HSkMC: 135.1;TIME: 147.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010558, CAB025784" Approved Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 160000000 "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Golgi apparatus" "CAB025784: , HPA010558: AB_1078439" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (3.95e-2)" "unprognostic (8.93e-2)" "unprognostic (3.99e-2)" "unprognostic (5.18e-2)" "unprognostic (9.53e-3)" "unprognostic (1.89e-2)" "unprognostic (2.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (3.69e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" 67.1 46.0 26.8 14.1 31.0 9.6 51.3 30.9 36.7 43.0 21.3 33.9 4.2 35.2 18.5 18.4 34.2 23.6 35.1 23.5 31.4 30.0 77.6 53.3 15.9 32.1 27.0 36.9 21.9 39.6 22.5 101.7 35.9 32.6 14.3 28.6 31.9 29.9 41.0 17.8 31.1 28.7 35.1 34.7 27.8 8.9 25.3 23.6 40.4 34.7 16.2 37.7 35.1 42.9 14.4 35.6 9.4 18.8 75.5 151.3 22.3 54.5 175.2 44.1 62.4 40.5 16.3 1.1 33.7 52.5 71.6 7.8 9.8 19.2 84.1 1.6 8.5 4.6 20.1 14.2 155.1 0.4 6.2 135.1 11.1 103.1 42.7 43.6 101.8 1.9 3.7 51.0 47.0 2.9 0.7 0.8 1.5 1.8 10.1 1.1 22.5 14.4 22.5 12.1 3.8 5.9 26.6 5.7 19.7 13.7 29.5 3.1 147.8 12.4 10.1 44.5 24.6 14.6 8.2 0.5 28.9 1.1 31.1 0.0 3.9 0.1 0.7 3.4 0.3 0.8 3.7 0.8 2.1 0.4 16.7 4.8 0.6 0.8 0.5 1.9 4.1 4.0 26.8 31.0 30.9 36.7 23.5 31.4 32.1 27.0 35.9 35.1 25.3 42.9 221.6 134.6 149.8 59.4 30.0 103.9 98.0 60.6 71.2 56.5 202.4 81.3 81.5 124.4 105.4 68.0 35.5 77.9 33.1 34.5 7.9 85.3 12.3 76.4 227.6 256.2 19.8 41.1 25.7 62.0 75.5 285.5 59.1 580.3 32.9 58.6 808.5 219.8 56.0 16.8 70.0 34.1 46.8 93.7 99.1 16.7 105.9 60.3 80.0 188.3 45.8 190.8 7.2 75.4 64.2 80.8 35.6 130.5 100.6 163.9 33.6 52.2 80.3 39.3 98.6 158.7 150.3 54.4 38.6 44.9 83.5 101.8 75.5 228.7 17.1 106.1 INSC ENSG00000188487 "INSC spindle orientation adaptor protein" Q1MX18 11 15112424-15247208 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "parathyroid gland: 25.3" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.9;Early spermatids: 4.6;Exocrine glandular cells: 3.1;Oligodendrocyte precursor cells: 8.0;Pancreatic endocrine cells: 10.9;Proximal tubular cells: 8.9" "Cancer enhanced" "Detected in some" "melanoma: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 11.7;hTERT-HME1: 6.0;Karpas-707: 3.3;LHCN-M2: 3.6;TIME: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA039769 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039769: AB_10697556" "unprognostic (1.64e-2)" "unprognostic (6.54e-2)" "unprognostic (1.45e-3)" "unprognostic (1.59e-1)" "unprognostic (6.00e-2)" "unprognostic (4.59e-3)" "unprognostic (6.88e-2)" "unprognostic (3.44e-3)" "unprognostic (3.69e-1)" "unprognostic (3.59e-2)" "unprognostic (2.63e-1)" "unprognostic (2.31e-1)" "unprognostic (3.30e-3)" "unprognostic (2.31e-1)" "unprognostic (1.35e-1)" "unprognostic (2.50e-2)" "unprognostic (5.00e-2)" 0.2 0.8 0.2 1.0 0.1 0.6 0.2 0.1 0.2 1.1 0.1 4.7 2.1 0.1 0.1 0.5 0.3 0.6 1.2 0.1 0.2 0.3 0.2 0.9 0.0 0.3 0.2 0.1 0.9 25.3 0.2 0.0 0.2 1.0 1.8 0.0 0.5 1.0 0.0 0.1 3.0 0.5 0.2 0.1 2.4 0.7 0.1 0.2 0.3 0.1 0.0 0.8 0.8 0.2 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.4 0.0 0.0 0.0 0.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.5 0.6 6.0 0.0 0.0 0.0 0.0 3.3 3.6 0.0 0.0 0.2 0.0 0.1 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 1.0 0.0 0.0 1.5 0.2 0.0 0.5 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.2 0.3 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.9 0.1 4.6 0.2 0.0 0.1 1.8 0.0 0.5 3.1 0.0 0.9 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.0 0.0 10.9 0.0 0.0 0.1 0.2 0.0 8.9 0.0 0.0 0.0 0.0 1.1 1.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 2.6 IPO11 RanBP11 ENSG00000086200 "Importin 11" Q9UI26 5 62403972-62628582 "Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 68.4;Hepatic stellate cells: 65.0;Inhibitory neurons: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 22.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065346, HPA067097" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA065346: , HPA067097: AB_2685776" "unprognostic (9.29e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (3.35e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (4.28e-5)" "unprognostic (4.26e-2)" "unprognostic (6.45e-2)" "unprognostic (1.26e-3)" "unprognostic (9.63e-2)" "unprognostic (5.09e-2)" "unprognostic (8.38e-3)" "unprognostic (1.62e-1)" "unprognostic (1.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.24e-2)" 16.0 9.1 13.4 9.7 13.7 6.6 14.4 13.6 14.6 10.6 16.3 9.2 6.9 9.4 8.5 12.0 10.2 10.7 14.7 14.7 13.7 11.9 11.4 7.7 10.4 14.1 13.7 9.4 8.6 13.4 6.0 16.5 13.6 9.0 8.6 6.3 8.5 8.4 12.6 8.8 7.9 11.0 14.4 13.4 8.5 21.4 13.9 10.0 14.0 14.4 10.1 13.4 9.9 15.7 27.1 25.4 22.3 34.6 17.0 23.4 30.9 28.4 20.5 29.1 31.9 27.5 20.2 45.3 22.2 28.9 35.5 21.4 47.3 32.0 45.6 17.5 24.6 21.6 24.5 24.4 12.8 23.7 11.6 16.7 17.7 34.3 35.7 13.7 113.8 22.4 41.5 14.5 27.9 26.0 26.1 32.2 28.0 15.4 14.5 31.6 33.7 41.6 17.7 26.4 24.1 13.9 24.8 19.3 21.0 21.9 24.9 17.0 51.8 17.4 19.3 19.8 26.4 11.3 20.0 31.3 21.2 33.4 21.3 16.5 2.4 2.2 3.8 3.8 4.5 3.3 3.9 3.9 4.0 4.8 5.5 4.0 2.5 22.7 7.0 2.4 2.8 3.6 13.4 13.7 13.6 14.6 14.7 13.7 14.1 13.7 13.6 14.4 13.9 15.7 39.6 9.6 3.7 35.9 11.8 8.5 4.2 3.3 13.6 4.2 6.2 4.8 13.2 5.7 4.5 7.3 2.1 7.6 7.9 2.7 3.9 4.2 42.2 8.4 7.0 40.0 3.0 21.7 68.4 5.5 6.7 7.6 6.1 5.6 13.3 9.6 65.0 6.2 5.2 5.0 55.0 4.4 2.0 6.5 6.4 25.3 5.6 7.4 3.6 20.6 2.6 3.9 10.3 28.1 48.3 3.3 1.7 4.1 10.7 5.2 2.6 3.6 25.6 4.9 6.6 9.7 8.7 14.6 16.2 10.9 8.8 5.1 8.8 4.6 5.7 4.8 IQGAP1 "HUMORFA01, KIAA0051, p195, SAR1" ENSG00000140575 "IQ motif containing GTPase activating protein 1" P46940 15 90388242-90502239 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013302, HPA014055" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 1500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cell Junctions" "CAB013302: AB_2533146, HPA014055: AB_1851856" "unprognostic (2.83e-1)" "unprognostic (7.73e-2)" "unprognostic (1.85e-1)" "unprognostic (1.02e-2)" "unprognostic (5.95e-2)" "unprognostic (4.24e-2)" "unprognostic (7.07e-2)" "unprognostic (1.17e-1)" "unprognostic (3.82e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (2.02e-1)" "unprognostic (1.03e-2)" "unprognostic (1.87e-1)" "unprognostic (1.25e-3)" 57.3 31.1 14.4 69.3 30.0 69.7 51.6 19.8 20.5 62.0 26.9 67.1 32.3 72.2 21.3 75.6 45.1 55.0 22.9 17.0 21.5 35.6 18.8 74.2 58.9 29.0 24.6 39.6 30.1 49.7 12.1 79.8 28.1 36.2 66.9 7.1 72.2 38.0 15.0 64.9 37.9 81.3 16.5 57.7 52.6 13.0 27.9 65.4 64.3 25.4 63.4 63.5 31.4 63.4 148.9 81.5 39.8 46.6 99.3 128.4 229.6 139.7 127.0 124.7 132.4 93.6 150.5 82.7 66.2 231.5 111.4 259.2 80.6 153.5 149.5 106.4 56.6 55.5 145.8 34.3 120.2 102.9 113.6 76.2 139.5 147.2 206.5 152.7 172.8 53.0 49.0 112.8 192.3 76.5 55.4 30.8 51.6 235.8 45.6 67.5 106.5 72.1 126.9 233.8 49.5 37.3 195.1 96.9 100.7 162.8 85.1 86.5 224.2 141.1 73.4 120.4 145.6 43.3 67.0 82.4 128.3 98.5 77.5 30.6 27.5 20.0 21.8 25.2 19.3 12.6 13.5 18.9 23.3 12.5 7.9 14.0 89.9 27.6 31.0 13.8 16.1 16.9 14.4 30.0 19.8 20.5 17.0 21.5 29.0 24.6 28.1 16.5 27.9 63.4 180.9 266.0 286.3 36.2 129.2 103.0 124.9 87.7 72.8 4.6 115.1 88.4 18.0 54.3 167.2 77.3 16.7 89.7 215.3 204.5 7.9 95.9 8.8 133.8 127.9 135.7 60.7 46.7 39.7 98.7 159.4 116.5 91.7 242.0 209.3 130.2 95.3 11.6 149.0 1.7 24.4 121.1 63.1 407.5 175.1 13.2 47.8 261.6 71.2 60.9 272.2 13.5 200.8 9.5 316.0 128.1 112.1 48.2 137.3 98.6 72.7 19.6 134.2 30.2 78.9 108.8 131.0 18.9 32.6 99.3 113.4 95.6 176.8 56.0 152.0 151.5 ITGA10 ENSG00000143127 "Integrin subunit alpha 10" O75578 1 145891208-145910111 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Endothelial cells: 22.7;Hepatic stellate cells: 55.3;Horizontal cells: 20.2;Late spermatids: 44.8;Microglial cells: 19.7" "Cancer enriched" "Detected in many" 4 "melanoma: 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 50.7;HSkMC: 46.3;hTERT-HME1: 41.0;LHCN-M2: 72.6;TIME: 125.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "prognostic favorable (7.18e-4)" "unprognostic (4.53e-1)" "unprognostic (4.44e-3)" "unprognostic (2.32e-2)" "unprognostic (3.60e-2)" "unprognostic (2.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.84e-1)" "unprognostic (4.37e-1)" "unprognostic (5.72e-3)" "unprognostic (6.48e-2)" "unprognostic (5.79e-2)" "unprognostic (2.58e-6)" "unprognostic (2.77e-3)" "unprognostic (1.54e-1)" "unprognostic (2.05e-5)" "unprognostic (2.57e-2)" 3.8 2.0 4.2 0.8 4.3 0.2 8.3 4.4 5.8 6.9 10.5 4.6 1.4 4.0 2.1 2.1 4.5 1.4 8.3 4.2 4.3 3.0 1.8 16.5 0.9 4.1 4.4 3.6 1.6 0.7 5.8 1.9 4.2 5.0 0.7 3.8 5.3 0.7 13.6 2.9 5.7 1.9 4.3 2.0 4.6 2.8 4.7 0.5 5.6 2.8 0.9 6.6 3.5 3.7 0.0 1.4 0.2 0.3 1.3 50.7 0.0 0.6 14.2 0.2 0.6 0.0 0.7 0.3 0.8 0.3 0.1 0.3 0.4 1.3 0.5 0.6 0.1 0.2 0.0 0.5 9.2 0.2 0.7 46.3 2.7 1.9 41.0 19.4 23.5 1.5 0.1 0.2 72.6 0.3 0.1 0.5 0.2 1.1 1.1 0.3 0.1 0.0 0.8 0.2 0.1 0.0 0.1 0.0 0.6 0.5 0.8 0.3 125.7 22.2 0.3 0.3 0.3 0.2 0.8 0.1 2.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 4.3 4.4 5.8 4.2 4.3 4.1 4.4 4.2 4.3 4.7 3.7 7.3 0.0 3.7 0.7 1.8 2.3 6.3 0.6 0.6 10.5 10.2 16.5 4.3 0.0 2.8 7.3 8.4 0.8 2.7 0.4 0.0 0.1 36.0 1.1 1.3 22.7 0.0 0.0 3.9 0.2 0.5 4.2 2.0 1.4 0.0 0.2 55.3 0.8 0.6 20.2 4.0 0.2 0.0 0.6 2.2 44.8 0.9 1.2 0.0 19.7 0.6 0.6 2.1 2.5 0.8 0.0 0.1 0.7 0.1 3.6 0.2 0.0 0.4 7.3 0.0 4.8 3.9 5.8 1.9 2.0 2.7 0.8 1.8 0.4 0.7 1.3 ITGA2 CD49B ENSG00000164171 "Integrin subunit alpha 2" P17301 5 52989340-53094779 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 406.2;Oligodendrocytes: 370.9;Pancreatic endocrine cells: 558.7;Prostatic glandular cells: 299.3;Urothelial cells: 363.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 91.4;HaCaT: 92.5;hTERT-RPE1: 83.2;HUVEC TERT2: 83.5;TIME: 71.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017690, HPA060991, HPA063556" Enhanced Approved Nucleoplasm,Cytosol Yes No 43000000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "CAB017690: AB_1124939, HPA060991: AB_2684405, HPA063556: AB_2685040" "unprognostic (8.35e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "unprognostic (3.70e-2)" "unprognostic (2.67e-3)" "unprognostic (2.38e-2)" "unprognostic (1.87e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (4.27e-1)" "unprognostic (3.88e-2)" "unprognostic (2.87e-2)" "unprognostic (1.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.11e-1)" 1.4 12.8 2.4 4.9 6.7 0.4 7.8 4.4 3.7 5.0 0.9 6.1 7.7 4.9 7.4 11.0 2.6 9.0 1.1 2.4 4.2 9.8 0.5 12.5 0.9 4.8 4.9 1.0 1.6 9.3 1.2 4.8 5.4 6.6 5.9 2.4 10.4 11.1 0.5 17.1 7.7 2.4 3.3 6.8 7.5 0.4 4.8 4.3 2.3 0.7 4.6 15.6 8.0 12.9 60.4 15.4 1.3 0.8 3.9 7.1 4.5 60.2 91.4 2.2 3.6 29.0 41.8 0.1 9.8 25.4 33.5 92.5 4.9 67.1 8.5 0.0 4.4 4.3 3.7 17.5 13.3 0.7 1.3 2.9 11.4 59.2 10.5 83.2 83.5 3.1 0.1 0.2 1.6 11.4 0.6 0.1 3.7 15.7 29.6 0.0 0.4 0.1 18.9 32.0 0.6 3.2 3.2 4.1 6.1 2.3 9.6 0.2 71.2 10.8 6.3 1.7 12.1 0.0 0.1 0.1 64.0 0.0 48.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 6.7 4.4 3.7 2.4 4.2 4.8 4.9 5.4 3.3 4.8 12.9 7.4 57.7 13.7 9.1 0.6 151.0 406.2 141.3 56.9 2.7 24.4 39.0 1.3 15.7 133.2 53.3 4.2 1.9 0.9 23.2 9.8 144.0 0.1 20.3 5.0 39.0 13.8 0.0 0.5 169.3 2.2 11.6 13.3 90.6 1.3 45.4 5.3 0.2 0.3 0.0 0.9 37.8 20.3 0.0 6.1 0.2 1.2 2.5 12.4 14.0 1.1 14.7 0.0 0.0 370.9 558.7 20.3 0.0 2.6 299.3 20.6 3.8 103.6 4.3 0.0 4.4 12.1 0.0 1.3 57.0 37.2 0.4 5.8 23.7 30.9 363.9 ITGA5 "CD49e, FNRA" ENSG00000161638 "Integrin subunit alpha 5" P08648 12 54395261-54419266 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 398.8;smooth muscle: 361.9;urinary bladder: 386.5" "Cell type enhanced" "Detected in many" "Endothelial cells: 101.5;Extravillous trophoblasts: 391.9;Hepatic stellate cells: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 89.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 615.4;HUVEC TERT2: 1360.8;TIME: 1277.7;U-87 MG: 623.6" "Region enriched" "Detected in many" 5 "basal ganglia: 10.4" "Low region specificity" "Detected in many" "HPA002642, CAB009008" Enhanced NA NA 26000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB009008: AB_647474, HPA002642: AB_1078469" "unprognostic (7.51e-3)" "prognostic unfavorable (4.07e-6)" "prognostic unfavorable (8.43e-4)" "unprognostic (1.58e-1)" "unprognostic (8.51e-3)" "prognostic unfavorable (2.91e-4)" "prognostic unfavorable (2.23e-5)" "prognostic unfavorable (2.44e-4)" "unprognostic (2.76e-2)" "unprognostic (6.19e-2)" "unprognostic (8.99e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (1.32e-8)" "unprognostic (2.11e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (8.89e-4)" "unprognostic (2.18e-3)" 114.4 47.1 8.7 136.2 9.2 46.4 69.1 9.2 13.8 64.0 9.7 398.8 15.3 106.1 5.0 72.3 71.1 50.8 113.9 8.5 9.0 26.6 48.6 121.7 17.5 11.3 9.9 39.3 20.9 14.9 10.5 91.6 11.3 141.9 40.6 1.3 24.5 114.9 29.1 50.5 87.6 361.9 10.6 16.3 90.8 4.0 17.1 13.2 40.5 25.7 12.5 386.5 76.9 9.8 65.4 23.9 43.6 0.6 130.8 278.7 113.5 286.0 308.2 300.9 220.6 17.1 15.3 0.5 206.9 308.5 149.1 10.1 12.5 81.4 197.4 0.4 12.2 28.1 31.3 1.1 179.5 88.7 44.4 206.8 39.2 351.9 258.3 615.4 1360.8 15.6 25.6 0.8 165.4 6.4 13.7 99.2 18.1 4.2 19.1 13.7 29.2 6.2 46.9 1.1 0.1 0.6 57.7 4.3 2.2 93.8 7.1 79.9 1277.7 353.0 62.3 85.9 121.5 0.3 3.6 0.7 623.6 83.0 118.5 16.4 64.9 0.5 14.2 27.3 11.2 0.1 10.9 10.9 62.6 0.3 7.7 6.6 89.1 26.4 24.0 3.4 4.9 42.9 8.7 9.2 9.2 13.8 8.5 9.0 11.3 9.9 11.3 10.6 17.1 9.8 58.3 3.2 4.4 1.6 2.7 14.3 3.4 11.3 4.0 1.1 6.1 2.8 16.3 14.3 4.9 0.0 0.0 5.4 19.6 0.0 0.0 34.0 0.3 1.7 32.1 101.5 0.0 3.4 1.4 3.4 391.9 45.0 0.5 3.0 19.7 5.1 88.9 27.1 28.4 0.0 1.2 0.0 2.0 22.8 58.5 0.5 6.5 38.5 10.6 14.0 24.6 0.0 21.6 0.0 0.2 8.8 0.0 4.5 8.7 3.6 0.0 0.2 1.8 1.1 13.1 11.1 30.7 0.2 0.7 1.3 10.7 34.6 14.3 2.4 0.0 2.0 ITPR2 "CFAP48, IP3R2" ENSG00000123104 "Inositol 1,4,5-trisphosphate receptor type 2" Q14571 12 26335352-26833194 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.3" "Cell type enhanced" "Detected in many" "Astrocytes: 551.4;Excitatory neurons: 287.2;Microglial cells: 802.9;Oligodendrocyte precursor cells: 441.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 32.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059144, HPA062260" Uncertain Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" Nucleoplasm "HPA059144: AB_2683925, HPA062260: AB_2684728" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-1)" "unprognostic (2.25e-1)" "unprognostic (2.37e-2)" "unprognostic (3.59e-3)" "unprognostic (8.70e-2)" "unprognostic (1.66e-1)" "unprognostic (8.61e-2)" "unprognostic (2.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.54e-2)" "unprognostic (2.82e-1)" "unprognostic (9.13e-2)" "unprognostic (3.99e-2)" "unprognostic (3.76e-1)" 8.3 10.4 10.5 8.1 7.3 6.0 17.3 6.3 9.7 4.8 3.4 6.2 5.3 5.2 5.7 7.4 5.5 5.5 3.7 7.7 8.7 12.6 44.3 5.6 7.9 19.1 13.2 5.9 7.7 11.4 2.2 10.9 14.9 5.5 6.6 8.8 16.9 2.9 1.8 10.2 4.9 4.5 13.1 6.7 5.2 2.5 16.1 20.1 4.3 4.1 6.8 4.9 4.7 15.6 4.9 2.0 2.9 4.6 8.5 8.6 3.0 4.4 6.1 3.0 3.1 0.2 2.4 16.5 2.7 5.9 3.3 5.2 15.1 9.3 4.0 3.9 5.1 13.5 4.4 27.1 7.9 12.0 5.8 8.1 1.2 6.3 11.6 6.2 28.5 6.5 6.4 5.1 3.9 4.0 8.6 17.8 12.2 4.4 1.5 2.9 7.0 10.7 7.3 7.4 0.9 4.5 19.8 3.5 11.4 11.3 7.7 6.0 62.6 6.0 2.3 5.9 5.7 4.9 4.2 31.2 5.7 5.6 3.9 32.4 6.4 9.9 2.9 2.7 2.5 5.4 2.6 2.4 1.4 5.0 3.0 2.7 17.3 4.8 4.3 11.9 4.4 1.0 10.5 7.3 6.3 9.7 7.7 8.7 19.1 13.2 14.9 13.1 16.1 15.6 27.1 48.1 52.9 551.4 45.7 20.9 17.8 3.3 31.3 3.2 87.0 57.1 24.5 34.3 8.6 23.9 146.0 21.0 39.1 7.7 7.9 20.8 3.1 13.3 64.9 38.5 78.5 33.4 287.2 23.4 9.5 20.3 16.8 22.7 44.4 60.0 25.0 123.7 39.5 0.0 99.1 46.1 32.6 46.3 8.2 6.7 18.0 68.7 33.8 802.9 28.2 13.0 41.2 441.8 22.3 17.6 37.0 17.7 83.6 25.9 14.5 14.6 5.0 64.7 0.0 22.7 17.6 3.6 6.3 54.3 26.7 27.9 29.2 43.4 11.7 15.8 ITPRIP "bA127L20.2, DANGER, KIAA1754" ENSG00000148841 "Inositol 1,4,5-trisphosphate receptor interacting protein" Q8IWB1 10 104309698-104338465 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 203.2" "Cell type enhanced" "Detected in many" "Adipocytes: 98.0;Hepatic stellate cells: 82.1;Squamous epithelial cells: 108.4;Suprabasal keratinocytes: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 103.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043626 Uncertain Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA043626: AB_10963078" "unprognostic (2.45e-2)" "unprognostic (3.06e-1)" "unprognostic (1.59e-2)" "unprognostic (3.22e-2)" "unprognostic (1.08e-2)" "unprognostic (4.20e-1)" "unprognostic (7.87e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (9.74e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (4.00e-2)" "unprognostic (5.37e-3)" "unprognostic (1.01e-3)" "unprognostic (2.65e-1)" "unprognostic (2.75e-1)" "unprognostic (2.11e-3)" 36.3 13.7 5.7 16.9 5.9 203.2 25.4 5.3 10.5 31.6 15.5 13.6 3.1 16.3 3.7 52.9 15.1 21.2 72.5 5.5 6.6 18.0 13.3 38.5 10.4 8.0 6.3 29.1 9.4 8.0 15.9 26.8 6.4 14.0 5.0 1.7 14.1 9.0 10.1 66.3 8.8 18.2 7.0 12.6 12.3 7.4 8.0 12.8 21.1 10.4 11.9 23.7 43.5 7.7 6.4 16.1 19.2 8.6 32.8 31.4 10.9 35.0 75.9 25.8 32.0 1.2 2.8 11.2 7.7 22.5 51.2 20.7 6.5 17.4 26.6 9.6 7.6 6.6 24.6 4.9 64.3 15.9 12.3 29.2 103.5 53.8 42.8 29.9 48.7 11.4 28.4 21.5 32.0 2.7 3.1 17.0 14.3 2.2 17.9 14.3 9.9 6.8 10.6 2.8 10.7 7.0 6.7 7.8 16.0 11.6 0.6 11.8 82.7 51.9 13.6 34.5 34.5 7.8 9.8 7.3 38.0 27.9 24.8 4.4 9.5 14.0 4.5 5.8 4.5 2.5 2.7 2.6 6.2 2.8 3.2 2.9 30.6 5.0 5.8 4.2 2.3 21.3 5.7 5.9 5.3 10.5 5.5 6.6 8.0 6.3 6.4 7.0 8.0 7.7 98.0 3.2 8.3 1.3 9.0 37.9 15.3 13.2 44.3 0.0 3.0 2.4 7.8 1.5 9.0 3.7 0.0 7.3 37.0 1.7 0.0 3.7 6.3 11.7 10.0 42.5 0.0 8.8 0.6 2.4 22.6 15.5 3.6 46.7 20.3 3.6 82.1 2.3 10.8 0.0 0.4 2.6 2.0 17.2 20.6 1.6 5.0 28.1 8.8 6.5 7.0 3.8 10.3 0.5 0.9 3.0 0.5 5.7 13.6 5.8 0.2 0.5 5.2 0.6 13.1 6.3 14.7 8.1 1.8 108.4 72.7 5.1 23.8 4.4 1.1 20.5 JAK1 "JAK1A, JAK1B, JTK3" ENSG00000162434 "Janus kinase 1" P23458 1 64833229-65067754 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 700.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 336.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013088 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "CAB013088: " "prognostic favorable (9.63e-4)" "unprognostic (1.24e-1)" "prognostic favorable (2.81e-4)" "unprognostic (5.10e-2)" "unprognostic (1.16e-1)" "unprognostic (4.21e-2)" "unprognostic (1.53e-1)" "unprognostic (7.00e-3)" "unprognostic (8.40e-2)" "unprognostic (7.88e-3)" "unprognostic (1.66e-2)" "unprognostic (8.84e-2)" "prognostic favorable (2.67e-4)" "unprognostic (2.35e-1)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "unprognostic (3.51e-1)" 99.6 38.2 44.8 73.9 42.6 51.4 60.7 46.7 45.4 58.2 61.7 50.5 33.9 56.7 60.8 38.7 40.7 64.2 49.5 46.0 53.9 55.4 86.6 62.1 110.1 56.0 47.0 77.1 46.7 55.0 35.6 57.0 49.1 42.2 54.5 41.7 34.2 55.2 83.4 79.2 50.8 64.2 44.0 88.3 49.5 46.8 59.8 103.8 45.0 118.6 101.7 81.2 39.3 45.5 50.4 66.2 27.7 3.0 336.8 177.2 35.1 76.3 116.1 64.6 75.7 21.4 27.7 76.5 59.1 142.8 118.7 27.8 19.4 63.6 93.8 102.7 29.5 104.0 32.1 56.2 126.6 40.2 68.4 159.9 92.6 97.2 103.0 78.4 208.7 37.0 37.9 78.9 80.1 31.2 22.3 39.6 18.6 65.3 37.4 30.5 77.8 28.5 213.8 84.9 19.8 57.9 107.4 51.6 52.9 56.6 104.3 28.6 180.8 74.7 34.1 174.2 42.0 47.7 23.6 60.4 70.5 57.9 34.1 162.4 52.1 146.8 94.0 66.3 105.7 89.1 90.2 100.7 69.4 73.1 97.0 80.6 177.9 305.4 76.2 55.0 117.1 130.8 44.8 42.6 46.7 45.4 46.0 53.9 56.0 47.0 49.1 44.0 59.8 45.5 211.2 51.3 94.9 62.3 219.8 116.6 150.7 91.3 78.0 37.0 66.2 71.6 112.8 87.2 84.2 112.2 22.9 9.0 345.0 89.2 43.0 171.3 125.2 90.1 167.0 183.0 66.4 52.8 59.6 213.8 105.2 131.9 91.3 151.2 57.0 48.7 174.2 91.4 58.5 21.9 85.3 62.0 69.2 160.2 148.9 101.7 96.0 177.9 49.8 80.6 234.8 53.5 700.3 61.3 42.7 217.5 58.6 84.7 175.2 183.8 53.7 79.0 61.9 38.6 164.3 70.6 191.8 40.8 53.1 71.2 166.1 12.2 256.0 95.7 47.6 200.1 JCAD KIAA1462 ENSG00000165757 "Junctional cadherin 5 associated" Q9P266 10 30012803-30115494 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 106.8;Endothelial cells: 30.3;Granulosa cells: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 29.3;HUVEC TERT2: 29.9;LHCN-M2: 24.9;TIME: 67.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017956 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" "HPA017956: AB_1852408" "unprognostic (1.78e-1)" "unprognostic (8.33e-2)" "unprognostic (5.37e-2)" "unprognostic (8.07e-2)" "unprognostic (6.32e-2)" "unprognostic (7.09e-2)" "unprognostic (9.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (1.33e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (2.54e-4)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.34e-2)" 31.2 7.5 13.5 5.2 21.2 0.1 13.0 5.1 13.0 6.5 3.1 36.0 1.4 17.3 7.5 5.9 12.5 10.4 18.3 10.8 7.2 6.7 1.8 24.2 3.5 12.5 8.4 10.9 16.9 4.9 4.5 33.6 10.1 7.8 3.9 13.1 2.4 9.5 9.9 3.7 3.7 17.3 7.3 0.9 4.5 14.0 13.3 6.1 13.6 14.8 1.8 18.3 4.4 8.1 15.3 6.7 5.9 0.0 3.7 0.9 8.6 8.1 8.5 1.2 2.0 2.6 0.1 0.0 0.6 29.3 1.7 0.3 1.6 0.5 3.3 1.7 3.6 0.0 0.0 0.1 16.0 0.0 1.0 9.1 0.2 19.9 1.5 0.5 29.9 0.4 0.0 0.0 24.9 0.5 0.0 0.7 1.2 0.9 10.2 0.0 3.3 0.0 1.2 0.3 0.8 0.1 0.3 0.1 0.0 8.4 0.0 1.4 67.8 14.9 3.6 4.7 0.7 6.2 0.8 0.0 3.5 10.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 21.2 5.1 13.0 10.8 7.2 12.5 8.4 10.1 7.3 13.3 8.1 106.8 0.0 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 16.4 0.0 1.3 8.5 30.3 0.0 0.0 0.0 0.4 0.9 2.2 0.0 0.8 1.3 72.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 0.2 7.1 0.0 0.0 KANK3 "ANKRD47, FLJ46061" ENSG00000186994 "KN motif and ankyrin repeat domains 3" Q6NY19 19 8322584-8343262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 196.2;Endothelial cells: 83.8;Hepatic stellate cells: 55.3" "Cancer enhanced" "Detected in all" "testis cancer: 7.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "NK-cells: 1.2;T-cells: 1.0" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.1;TIME: 14.8;U-266/70: 5.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "olfactory bulb: 16.2" HPA051153 Approved Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA051153: AB_2681365" "unprognostic (1.56e-1)" "unprognostic (1.63e-4)" "unprognostic (1.54e-2)" "unprognostic (8.95e-3)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (1.82e-3)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-2)" "unprognostic (4.77e-1)" "prognostic favorable (1.69e-5)" "unprognostic (5.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.86e-1)" "unprognostic (3.24e-1)" 25.6 7.6 12.0 2.3 9.7 0.6 26.1 9.6 12.2 8.2 5.8 6.2 2.9 10.2 0.7 5.1 11.2 2.5 32.9 8.7 8.9 22.2 4.2 33.4 2.8 12.5 11.5 3.6 3.9 1.5 6.9 14.6 11.5 7.6 0.5 0.3 4.1 1.8 13.7 6.7 7.3 2.4 9.7 35.5 6.2 2.4 13.2 0.7 15.5 6.0 0.8 7.9 6.8 8.9 0.1 0.6 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.2 0.0 2.3 0.0 0.0 0.1 0.5 2.6 0.0 0.7 1.4 0.3 0.3 0.4 0.1 0.2 1.3 0.0 0.8 0.0 0.0 0.0 8.1 0.6 0.0 0.3 0.0 0.4 0.0 0.4 0.5 0.5 0.2 1.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.7 0.1 0.0 0.5 0.0 14.8 0.0 1.3 0.3 0.1 5.9 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 1.0 0.0 0.5 0.1 0.5 0.1 0.0 0.1 0.2 0.4 0.2 1.2 0.0 0.0 0.4 0.2 12.0 9.7 9.6 12.2 8.7 8.9 12.5 11.5 11.5 9.7 13.2 8.9 196.2 6.4 3.2 2.0 0.3 2.5 0.4 0.6 0.6 0.3 1.5 2.5 2.2 0.0 0.8 0.0 4.2 0.4 3.8 0.1 5.9 0.1 6.6 0.5 0.7 83.8 0.0 2.7 0.6 1.8 0.3 6.4 1.5 0.8 0.0 0.2 55.3 1.0 0.5 0.0 0.9 0.0 0.0 1.3 2.1 8.1 0.6 0.9 5.4 18.7 0.0 0.4 12.3 0.5 1.6 0.6 0.1 0.4 0.4 1.0 0.0 0.4 0.7 0.7 19.7 8.3 12.9 6.5 3.6 1.1 1.3 0.3 2.8 4.0 0.1 0.8 KATNBL1 "C15orf29, FLJ22557" ENSG00000134152 "Katanin regulatory subunit B1 like 1" Q9H079 15 34140674-34210096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 128.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 128.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062573 Approved Supported "Nucleoplasm,Midbody,Cleavage furrow,Mitotic spindle" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Midbody, Mitotic spindle" "Nucleoplasm, Cleavage furrow" "HPA062573: AB_2684796" "unprognostic (5.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.35e-2)" "unprognostic (2.91e-2)" "unprognostic (2.01e-2)" "unprognostic (1.38e-1)" "unprognostic (1.14e-1)" "unprognostic (1.75e-1)" "unprognostic (1.01e-1)" "unprognostic (5.16e-2)" "unprognostic (3.94e-3)" "unprognostic (8.00e-3)" "prognostic unfavorable (4.60e-5)" "unprognostic (2.71e-2)" "unprognostic (7.23e-2)" "unprognostic (2.42e-1)" "unprognostic (1.43e-1)" 22.0 12.1 16.3 22.9 16.6 16.3 20.8 25.0 20.8 22.5 22.4 19.9 15.9 20.7 19.0 39.9 16.8 15.9 13.4 15.8 14.9 17.0 17.6 18.4 17.6 15.0 13.8 14.4 14.0 14.5 12.1 32.4 16.0 16.9 21.2 31.2 14.6 13.6 13.2 31.4 15.7 25.4 12.9 18.6 17.7 18.0 18.2 15.2 12.5 13.0 20.3 17.8 27.7 25.3 37.1 31.5 49.7 33.4 39.5 39.0 37.0 49.6 30.0 38.7 38.4 17.8 19.9 17.6 31.2 32.2 54.5 47.5 24.9 28.5 45.8 36.9 12.6 31.8 34.6 21.6 27.0 33.9 33.1 23.6 40.8 26.1 51.3 39.7 70.6 45.4 34.3 36.7 53.1 17.6 21.4 27.4 35.8 47.4 25.0 32.3 30.3 16.1 35.9 49.5 28.1 24.8 30.1 21.9 14.7 49.2 27.0 38.8 40.4 51.9 26.7 46.8 39.7 21.5 32.5 37.1 46.5 35.7 38.9 62.8 18.2 29.7 18.4 17.3 23.3 23.9 19.6 18.8 20.7 25.6 21.5 19.2 128.5 13.2 11.5 28.4 17.9 12.0 16.3 16.6 25.0 20.8 15.8 14.9 15.0 13.8 16.0 12.9 18.2 25.3 59.7 38.5 25.2 83.9 41.7 41.3 65.2 60.5 34.7 57.0 42.1 43.1 12.8 24.3 51.6 25.8 52.1 58.6 42.3 30.6 33.2 59.1 75.4 40.5 53.3 47.0 23.9 39.8 104.3 54.5 86.2 38.8 39.3 50.8 44.9 68.7 37.9 20.8 39.1 67.3 96.7 35.6 52.9 27.6 48.8 59.2 31.7 36.2 32.0 64.6 49.9 53.1 27.8 86.0 114.4 105.3 37.4 33.1 41.1 116.8 21.4 41.6 49.6 44.7 59.2 52.2 45.3 47.8 44.3 45.0 54.3 179.5 39.7 31.6 39.1 132.6 KCNAB1 "AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3" ENSG00000169282 "Potassium voltage-gated channel subfamily A member regulatory beta subunit 1" Q14722 3 156037701-156539138 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 52.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.8;Excitatory neurons: 108.6;Inhibitory neurons: 605.4;Oligodendrocyte precursor cells: 206.6;Oligodendrocytes: 97.5;Sertoli cells: 78.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HEL: 3.4;hTEC/SVTERT24-B: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036110, HPA044550" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Nucleoplasm, Plasma membrane" "HPA036110: , HPA044550: AB_10797032" "unprognostic (1.52e-1)" "unprognostic (3.73e-1)" "unprognostic (1.33e-1)" "unprognostic (2.98e-4)" "unprognostic (1.24e-2)" "unprognostic (1.64e-1)" "unprognostic (1.81e-1)" "unprognostic (2.83e-2)" "unprognostic (8.51e-2)" "unprognostic (3.72e-2)" "unprognostic (5.87e-2)" "unprognostic (9.70e-2)" "unprognostic (2.17e-3)" "unprognostic (2.60e-1)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-1)" 15.8 6.3 12.7 1.2 52.7 1.6 7.3 15.5 17.3 8.4 4.2 4.1 1.7 5.4 12.8 2.2 4.3 2.9 5.5 25.9 11.6 1.8 2.6 3.3 0.9 7.2 12.1 2.9 4.0 2.0 1.8 1.3 7.2 22.4 1.8 12.8 3.9 19.2 2.0 2.2 2.7 2.7 8.4 5.2 1.6 3.1 14.1 1.8 28.7 5.1 0.3 2.9 5.0 15.4 0.5 0.5 0.7 0.2 0.0 0.0 1.4 1.2 0.0 0.0 0.1 0.9 0.1 0.4 0.7 0.0 0.3 0.3 0.0 0.0 0.0 0.4 1.0 3.4 0.6 1.6 0.0 1.0 0.2 0.0 0.0 5.2 0.0 1.1 2.1 0.5 0.1 0.3 0.2 0.1 0.3 0.6 1.1 1.5 0.2 0.6 0.7 2.8 0.0 0.2 0.8 0.8 0.3 0.6 0.7 0.5 0.8 0.5 2.2 0.8 0.5 1.4 1.2 1.8 0.4 0.4 2.6 1.1 1.0 0.8 0.1 0.0 0.4 0.2 0.8 0.2 0.4 0.3 0.2 0.2 0.3 0.3 0.0 0.3 0.3 1.2 0.5 0.1 12.7 52.7 15.5 17.3 25.9 11.6 7.2 12.1 7.2 8.4 14.1 15.4 7.2 0.0 0.0 7.5 0.7 0.8 0.3 0.0 0.0 85.8 1.4 1.4 4.3 0.0 0.7 0.0 31.3 0.1 0.5 0.1 0.0 0.4 13.7 0.6 2.4 2.8 0.0 0.0 108.6 0.0 0.0 3.8 0.0 2.1 0.0 0.4 0.7 0.0 4.6 0.0 605.4 0.0 0.0 11.1 1.0 7.0 0.0 1.2 1.8 24.4 0.0 2.7 0.0 206.6 97.5 0.0 0.0 2.6 2.3 0.2 0.0 0.1 0.0 6.7 78.9 1.3 73.3 0.3 4.2 1.2 0.9 0.1 0.5 0.2 0.0 0.2 KCTD12 "C13orf2, KIAA1778, PFET1" ENSG00000178695 "Potassium channel tetramerization domain containing 12" Q96CX2 13 76880175-76886405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 281.2;Endothelial cells: 192.2;Enteroendocrine cells: 386.7;Hofbauer cells: 218.9;Kupffer cells: 395.9;Macrophages: 221.3;monocytes: 206.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 3.9;myeloid DC: 3.7" "Group enriched" "Detected in many" 17 "dendritic cells: 3.7;granulocytes: 1.0;monocytes: 3.9" "Cell line enhanced" "Detected in many" "ASC diff: 111.4;HUVEC TERT2: 229.0;TIME: 186.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056987, HPA077376" Supported Approved Mitochondria NA NA 21000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA056987: , HPA077376: " "unprognostic (6.42e-2)" "unprognostic (2.67e-1)" "unprognostic (5.13e-1)" "unprognostic (1.04e-3)" "unprognostic (5.82e-2)" "unprognostic (3.98e-2)" "unprognostic (2.02e-1)" "unprognostic (1.32e-3)" "unprognostic (1.35e-2)" "unprognostic (1.90e-1)" "unprognostic (9.83e-3)" "unprognostic (1.23e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.11e-2)" "unprognostic (1.65e-2)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" 76.1 27.8 21.4 55.7 20.1 12.0 52.4 27.0 20.8 44.5 12.4 39.5 22.5 51.3 17.8 38.3 75.0 55.0 22.6 26.9 27.8 31.0 13.9 58.0 39.4 36.2 33.5 47.1 12.5 25.2 6.4 83.9 31.4 14.7 42.5 3.4 20.0 18.5 16.6 22.9 28.1 65.3 37.0 64.8 28.0 26.9 31.4 18.3 16.4 37.1 33.4 39.2 17.4 34.4 1.7 1.5 15.3 0.0 111.4 52.5 4.3 6.9 1.5 4.2 5.5 0.5 0.3 0.0 3.8 18.8 4.9 53.9 6.6 66.4 3.5 1.5 35.1 0.2 38.3 0.0 4.7 18.6 0.1 21.4 21.5 2.7 48.9 8.5 229.0 13.2 0.3 0.2 53.9 1.4 8.5 0.3 7.8 16.6 7.7 0.4 7.4 19.6 17.7 0.2 4.3 7.9 17.3 0.5 2.2 18.5 1.0 12.1 186.0 2.7 4.9 0.4 14.0 2.7 0.5 0.0 42.5 4.0 16.1 0.0 3.9 0.7 0.0 2.5 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 1.0 0.0 1.5 1.9 0.0 0.9 21.4 20.1 27.0 20.8 26.9 27.8 36.2 33.5 31.4 37.0 31.4 34.4 281.2 25.6 8.4 2.9 7.5 40.0 2.7 11.9 28.5 4.4 11.2 27.3 21.8 4.3 16.3 97.5 14.6 3.0 30.4 19.7 17.6 6.5 3.6 4.9 44.6 192.2 386.7 6.1 4.8 0.6 90.6 80.0 12.2 3.3 7.0 53.1 61.1 2.5 218.9 0.0 11.5 71.5 12.2 395.9 75.4 11.8 157.2 221.3 51.6 45.9 206.7 4.8 7.2 0.5 0.9 0.5 15.7 44.8 7.6 4.5 0.7 7.5 72.8 1.5 26.3 153.2 32.2 1.9 7.0 16.9 34.4 4.2 5.5 24.0 46.6 1.9 KCTD16 KIAA1317 ENSG00000183775 "Potassium channel tetramerization domain containing 16" Q68DU8 5 144170873-144485686 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 11.0" "Group enriched" "Detected in some" 15 "Excitatory neurons: 801.9;Inhibitory neurons: 788.9;Oligodendrocyte precursor cells: 362.4" "Cancer enhanced" "Detected in single" "renal cancer: 0.7" "Region enhanced" "Detected in many" "basal ganglia: 11.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.9;TIME: 6.2;U-87 MG: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044590, HPA050154" Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044590: AB_2679008, HPA050154: AB_2681034" "unprognostic (7.22e-2)" "unprognostic (3.63e-1)" "unprognostic (2.54e-2)" "unprognostic (6.81e-5)" "unprognostic (9.88e-2)" "unprognostic (1.21e-1)" "unprognostic (7.74e-3)" "unprognostic (3.23e-2)" "unprognostic (1.94e-2)" "unprognostic (9.57e-2)" "unprognostic (9.38e-3)" "unprognostic (6.20e-3)" "unprognostic (2.52e-8)" "unprognostic (1.55e-3)" "unprognostic (2.34e-1)" "unprognostic (5.80e-3)" "unprognostic (1.22e-2)" 0.0 0.5 1.1 0.0 11.0 0.0 0.0 0.0 6.5 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 5.1 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.5 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.5 0.4 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 6.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 11.0 0.0 6.5 5.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.0 40.8 0.0 0.0 0.0 0.3 0.0 14.3 0.0 0.1 0.7 1.5 0.0 0.0 2.1 0.1 0.0 0.1 0.0 4.3 9.7 0.3 0.1 0.6 0.0 0.0 801.9 5.5 0.0 0.9 0.0 0.0 0.0 0.1 0.4 0.0 0.1 20.2 788.9 0.4 0.0 0.0 0.5 5.3 0.0 0.0 0.0 16.9 0.1 0.8 0.0 362.4 34.9 1.8 0.0 0.0 0.0 0.0 0.1 0.8 0.9 2.9 0.0 0.1 0.4 4.8 2.2 0.0 0.0 0.0 0.1 0.1 0.2 0.0 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Adipocytes: 157.8;Endothelial cells: 143.8;Hepatic stellate cells: 158.1;Muller glia cells: 206.6" "Cancer enhanced" "Detected in all" "renal cancer: 27.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 74.8;TIME: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004028, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 11000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear membrane" "CAB004028: AB_2212507, HPA073577: " "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 41.6 11.7 2.7 4.3 3.8 0.0 26.1 2.8 4.1 14.8 10.4 6.3 2.2 39.5 2.9 4.0 17.9 5.6 20.6 2.1 2.8 15.7 9.2 23.5 2.8 3.2 3.6 5.2 6.2 8.6 11.0 30.9 3.5 11.7 1.0 16.4 5.3 10.0 6.5 5.9 7.5 7.5 3.3 4.4 8.4 1.8 4.5 1.0 34.4 4.6 1.0 8.6 7.5 3.4 0.0 0.0 4.4 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.5 0.0 0.0 0.9 0.0 0.0 0.4 0.2 74.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.8 2.8 4.1 2.1 2.8 3.2 3.6 3.5 3.3 4.5 3.4 157.8 0.0 4.9 0.0 1.4 2.5 0.5 0.1 1.8 11.7 1.3 2.5 9.4 1.5 18.4 0.0 0.0 0.1 0.8 0.0 0.0 0.5 0.8 0.4 2.6 143.8 0.0 2.7 0.1 0.0 0.1 8.3 0.0 0.8 2.5 0.0 158.1 3.3 0.4 0.0 1.3 0.0 0.0 10.6 2.1 0.9 0.0 1.2 7.2 7.5 0.0 206.6 0.0 0.0 6.1 0.5 0.0 0.4 1.3 0.5 0.0 0.0 3.9 7.9 0.0 0.9 7.5 0.3 0.9 0.8 2.7 0.1 0.6 1.6 0.0 1.4 KIAA1671 ENSG00000197077 KIAA1671 Q9BY89 22 24952730-25197448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 74.4;Excitatory neurons: 67.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.8" "Lineage enriched" "Detected in single" 4 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "OE19: 39.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018135 Approved Approved Microtubules NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Microtubules "HPA018135: AB_1859551" "unprognostic (1.67e-1)" "unprognostic (1.65e-3)" "unprognostic (1.14e-2)" "unprognostic (1.46e-2)" "unprognostic (7.34e-2)" "unprognostic (3.52e-2)" "unprognostic (8.71e-3)" "unprognostic (1.26e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (2.66e-2)" "unprognostic (7.68e-2)" "prognostic favorable (3.19e-6)" "unprognostic (6.72e-2)" "unprognostic (1.14e-1)" "unprognostic (7.54e-2)" "unprognostic (7.87e-2)" 10.7 13.7 12.4 5.1 13.2 0.8 22.5 2.8 17.9 10.3 8.6 16.0 14.4 6.6 5.2 25.9 20.0 14.8 11.3 20.0 7.7 11.0 34.1 12.2 5.5 6.7 8.3 8.5 10.1 10.3 11.2 4.1 3.9 13.2 14.2 15.5 25.9 15.5 25.1 28.0 16.8 6.8 6.5 3.8 12.4 4.9 13.5 15.6 26.6 22.1 8.9 8.9 18.7 5.6 25.2 15.7 3.3 5.9 0.1 0.1 2.6 0.1 0.1 1.4 0.1 12.6 9.0 0.1 11.7 1.1 6.9 29.8 25.5 25.2 1.0 0.2 10.6 0.1 16.7 16.9 3.3 0.1 1.3 0.6 22.4 7.9 24.3 16.6 28.9 0.5 0.3 0.1 3.4 11.6 0.1 0.1 5.2 39.9 8.3 1.1 26.6 4.9 16.3 10.8 8.0 6.7 20.3 14.0 1.3 10.8 7.6 0.2 19.5 1.4 27.0 16.6 4.5 0.1 0.4 0.1 10.0 0.0 4.3 0.2 0.0 0.0 1.8 0.0 0.2 0.0 0.5 1.3 0.0 0.1 0.2 0.8 0.2 0.4 0.0 0.1 0.1 0.3 12.4 13.2 2.8 17.9 20.0 7.7 6.7 8.3 3.9 6.5 13.5 5.6 27.7 12.8 21.9 74.4 1.1 10.8 21.1 16.2 18.2 4.2 25.4 16.5 11.9 25.8 19.2 5.5 22.9 0.2 3.0 62.9 0.0 18.9 2.6 31.2 3.5 28.5 7.2 5.3 67.8 18.9 0.1 4.9 22.4 30.2 1.3 4.2 29.6 47.8 2.4 16.8 22.9 12.3 6.1 1.9 5.9 3.5 7.2 1.6 10.6 43.1 0.6 21.6 0.0 12.5 3.4 21.4 34.1 9.1 0.6 18.2 34.1 8.8 32.0 17.6 0.0 11.0 9.3 6.8 8.8 27.3 14.5 1.0 6.6 6.6 20.1 29.2 KIF13B "GAKIN, KIAA0639" ENSG00000197892 "Kinesin family member 13B" Q9NQT8 8 29067278-29263124 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "brain: 64.5;parathyroid gland: 161.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 140.2;Oligodendrocytes: 371.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025023, HPA049655" Enhanced NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA025023: AB_1852471, HPA049655: AB_2732555" "unprognostic (1.37e-1)" "unprognostic (4.31e-1)" "prognostic favorable (8.92e-4)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "prognostic favorable (6.26e-4)" "unprognostic (1.04e-1)" "unprognostic (1.66e-1)" "unprognostic (1.21e-2)" "unprognostic (9.69e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (9.76e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.19e-1)" "unprognostic (1.81e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" 7.4 11.7 25.9 6.8 47.6 5.1 9.2 34.9 30.6 8.7 16.6 18.3 16.1 6.7 9.4 8.4 7.1 8.4 5.3 20.0 29.4 18.5 10.2 8.5 4.3 47.3 43.7 7.2 10.9 161.5 10.0 3.8 42.1 10.9 13.8 7.9 15.6 8.5 4.7 20.0 15.7 5.5 29.3 8.9 19.2 6.6 40.1 5.1 9.0 3.0 4.6 9.5 6.1 64.5 12.4 13.2 4.6 3.8 7.5 4.3 6.7 0.7 2.9 3.9 6.2 8.3 6.9 2.6 6.9 0.8 7.1 8.2 3.7 2.1 5.1 3.9 3.6 6.6 1.8 8.4 7.2 1.8 19.2 5.0 3.9 8.9 3.6 8.3 17.1 4.9 8.6 9.5 12.9 3.8 9.7 3.1 2.3 17.4 2.2 5.5 10.6 4.9 17.0 13.2 1.3 9.1 2.4 8.0 11.7 4.8 5.9 3.7 22.8 2.8 7.6 0.8 5.6 6.9 11.1 4.4 16.4 3.4 13.2 0.1 1.5 1.7 1.5 1.1 0.7 1.4 0.6 0.9 0.5 0.8 0.5 0.6 0.7 0.9 0.6 2.2 0.6 0.5 25.9 47.6 34.9 30.6 20.0 29.4 47.3 43.7 42.1 29.3 40.1 64.5 22.2 44.8 24.8 30.0 16.5 4.5 13.8 17.2 5.2 13.3 23.5 11.2 5.3 20.0 36.8 35.0 60.5 6.4 35.8 95.8 11.7 25.7 8.0 55.3 12.7 14.2 25.2 7.4 26.7 25.0 0.9 10.0 55.0 140.2 41.0 10.6 13.9 18.6 8.9 16.8 35.3 44.1 36.7 25.7 6.3 3.5 8.1 24.4 7.2 41.2 12.1 9.5 12.3 47.3 371.1 39.7 58.0 20.3 42.5 28.1 34.7 17.8 34.9 26.2 6.6 36.4 7.4 6.3 7.7 9.8 6.8 5.1 31.8 5.9 36.0 32.5 KIF1C "SAX2, SPAX2, SPG58" ENSG00000129250 "Kinesin family member 1C" O43896 17 4997950-5028401 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 244.8;choroid plexus: 142.7;heart muscle: 185.0;skeletal muscle: 561.0;tongue: 389.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 315.4;Distal enterocytes: 168.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024602, HPA045020" Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA024602: AB_1852480, HPA045020: AB_2679187" "unprognostic (3.89e-2)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (1.24e-2)" "unprognostic (3.74e-1)" "unprognostic (8.97e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-1)" "unprognostic (6.69e-2)" "unprognostic (8.31e-2)" "unprognostic (1.45e-1)" "unprognostic (4.90e-3)" "prognostic favorable (2.26e-9)" "unprognostic (1.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.41e-1)" "unprognostic (7.10e-3)" 54.6 18.6 200.1 25.1 230.9 6.3 36.3 184.0 210.0 33.9 142.7 63.3 53.3 44.4 7.9 75.7 31.5 28.0 185.0 164.4 175.0 37.9 46.4 49.6 10.0 219.0 216.9 24.1 51.6 55.1 10.5 18.6 197.0 36.4 33.2 4.3 38.3 36.7 561.0 53.4 51.4 36.3 200.7 26.5 51.2 17.7 200.8 11.3 38.7 389.2 16.7 51.4 37.3 244.8 104.1 97.6 32.2 69.4 74.5 44.5 51.0 80.8 64.3 63.2 38.3 70.7 24.5 16.6 46.7 127.2 41.2 105.3 58.4 107.2 44.6 40.2 68.7 12.0 124.1 57.4 50.7 4.9 34.6 46.0 109.9 85.2 58.0 59.6 87.2 14.5 45.9 28.4 62.6 61.5 14.7 8.0 25.1 68.1 63.4 15.1 54.1 17.2 55.7 71.9 7.8 15.3 114.2 63.0 34.9 30.6 62.0 14.9 185.5 84.8 63.7 62.2 99.3 10.8 9.9 8.9 62.6 20.9 43.0 0.5 0.4 0.7 0.2 0.4 0.2 0.4 0.2 0.2 0.3 0.4 0.2 0.2 1.2 0.3 0.2 0.2 0.3 0.1 200.1 230.9 184.0 210.0 164.4 175.0 219.0 216.9 197.0 200.7 200.8 244.8 24.8 54.5 50.6 6.5 6.8 16.8 19.0 25.6 12.5 12.5 24.8 14.2 315.4 48.6 28.1 25.8 0.0 14.8 6.5 168.9 19.6 32.2 71.6 13.0 15.1 37.8 14.4 4.4 5.7 43.1 14.0 21.9 51.0 29.3 12.7 21.6 37.1 82.7 16.1 23.5 7.3 77.3 12.2 18.5 11.0 32.1 16.8 11.9 16.0 10.3 16.1 7.7 6.2 4.5 5.0 63.0 83.8 42.5 11.4 44.1 92.9 42.9 18.4 5.8 6.6 35.0 35.1 18.7 23.6 21.3 20.2 23.3 7.9 12.4 65.4 36.6 KLF10 "EGRA, TIEG, TIEG1" ENSG00000155090 "Kruppel like factor 10" Q13118 8 102648784-102655725 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 409.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (6.67e-2)" "unprognostic (1.29e-2)" "unprognostic (4.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.42e-3)" "unprognostic (7.76e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.61e-5)" "unprognostic (4.88e-1)" "unprognostic (2.74e-2)" "unprognostic (3.44e-2)" "unprognostic (3.77e-1)" "unprognostic (6.60e-3)" "unprognostic (3.27e-2)" "unprognostic (8.23e-2)" "unprognostic (7.51e-3)" "unprognostic (1.06e-1)" 65.4 28.8 6.1 25.4 7.2 152.8 40.3 4.9 14.3 37.6 8.2 58.4 28.3 40.7 17.0 39.6 42.4 64.9 33.5 7.8 6.8 40.0 95.7 71.3 22.6 6.3 6.8 25.0 126.2 15.2 16.4 71.1 6.0 45.4 46.1 11.4 32.0 33.3 158.9 72.1 26.2 60.3 6.1 34.9 41.1 26.7 6.4 45.6 30.0 122.9 22.3 46.4 27.4 6.2 22.3 32.4 17.3 15.7 30.4 66.3 30.8 43.0 22.9 26.8 12.8 17.3 42.2 35.5 38.2 39.1 49.4 24.0 10.0 106.5 35.4 20.3 17.4 27.6 24.4 15.9 24.7 16.3 41.3 94.5 105.2 36.8 42.1 62.1 60.0 6.8 18.2 68.3 87.2 36.2 17.8 28.3 13.5 58.5 78.8 7.2 59.7 34.0 38.8 67.6 25.4 27.6 64.0 26.3 35.0 25.0 25.4 19.1 67.0 55.9 39.5 65.3 44.0 61.6 51.7 32.6 52.1 20.1 32.2 17.2 52.5 14.3 16.5 48.2 9.0 17.1 12.5 17.2 57.2 5.8 3.1 12.7 5.3 15.6 26.0 10.1 18.4 34.7 6.1 7.2 4.9 14.3 7.8 6.8 6.3 6.8 6.0 6.1 6.4 6.2 195.5 141.1 74.9 1.0 49.2 137.1 167.6 117.3 409.8 3.5 115.9 119.6 117.9 40.0 56.6 44.1 6.2 52.3 41.7 74.6 9.8 58.3 8.5 110.1 121.6 134.7 94.2 11.2 6.7 43.3 87.7 147.7 46.4 183.3 100.1 34.9 94.2 53.5 61.1 8.4 0.6 49.2 93.6 73.1 185.6 10.4 66.5 117.6 76.5 7.5 83.7 7.7 8.2 0.5 0.5 42.7 41.2 29.3 51.4 136.7 35.5 43.8 50.7 2.6 26.3 157.1 124.1 18.7 30.7 222.9 164.8 72.7 47.8 40.6 48.1 58.8 KLF2 LKLF ENSG00000127528 "Kruppel like factor 2" Q9Y5W3 19 16324826-16328685 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 1043.3;B-cells: 691.8;dendritic cells: 542.9;Endothelial cells: 511.8;Gastric mucus-secreting cells: 561.7;NK-cells: 466.5;Plasma cells: 806.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 26.8;TIME: 67.8;U-266/70: 45.6;U-266/84: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055964 Approved Approved Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA055964: AB_2682989" "unprognostic (3.22e-3)" "unprognostic (1.89e-2)" "unprognostic (3.13e-2)" "unprognostic (1.72e-3)" "unprognostic (1.04e-1)" "unprognostic (7.91e-3)" "prognostic favorable (8.55e-4)" "unprognostic (1.74e-1)" "unprognostic (3.09e-2)" "unprognostic (4.28e-2)" "unprognostic (4.90e-1)" "unprognostic (1.52e-1)" "unprognostic (9.76e-3)" "unprognostic (7.80e-2)" "unprognostic (1.76e-1)" "unprognostic (3.50e-1)" "unprognostic (7.56e-2)" 153.7 27.1 25.0 61.6 23.2 90.0 108.4 15.4 18.5 59.2 10.9 55.2 9.6 61.5 2.5 32.2 105.9 14.7 118.4 13.6 17.9 41.6 13.4 110.8 45.4 27.3 34.1 152.6 12.5 5.6 28.8 22.4 24.2 41.8 5.0 0.6 35.7 6.8 52.0 65.5 44.6 19.5 14.1 70.9 73.1 18.3 27.9 13.0 53.5 20.5 8.3 86.9 63.8 15.5 7.5 1.8 0.1 1.6 0.4 1.0 2.9 16.6 1.8 5.5 1.8 0.1 24.0 0.7 3.7 6.7 0.9 2.5 0.5 0.0 1.5 0.6 2.0 0.0 1.4 0.2 4.2 0.0 12.1 1.2 0.2 1.4 0.3 7.1 10.9 14.7 0.5 15.4 2.4 0.4 1.5 3.2 0.2 7.3 2.2 0.5 4.3 26.8 0.2 0.3 0.5 0.2 0.9 12.3 10.4 0.1 0.5 8.6 67.8 12.9 9.4 1.0 23.8 45.6 49.3 1.6 5.7 0.0 5.8 63.2 8.3 25.1 42.7 32.9 34.9 44.7 56.6 43.9 3.3 47.5 53.5 44.4 79.5 28.7 29.1 0.6 59.4 20.5 25.0 23.2 15.4 18.5 13.6 17.9 27.3 34.1 24.2 14.1 27.9 15.5 1043.3 35.3 60.0 1.0 691.8 23.8 25.9 7.4 30.1 5.8 69.6 51.8 47.9 31.5 9.0 3.7 8.4 4.5 542.9 151.7 0.0 10.3 2.3 53.8 31.1 511.8 46.4 35.0 0.8 6.0 7.6 350.6 561.7 20.4 33.6 8.1 393.3 10.6 91.3 0.0 1.9 110.5 2.0 242.4 58.5 6.3 89.5 272.9 64.0 48.7 74.1 7.6 466.5 0.5 0.3 64.3 61.3 73.0 806.5 10.7 4.8 1.9 18.2 8.8 65.7 460.9 235.3 0.8 2.9 22.1 26.3 6.6 417.8 57.9 33.7 12.9 KLHL3 KIAA1129 ENSG00000146021 "Kelch like family member 3" Q9UH77 5 137617500-137736089 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.7" "Cell type enhanced" "Detected in many" "Early spermatids: 44.1;Excitatory neurons: 91.9;Inhibitory neurons: 56.1;Late spermatids: 60.7;Muller glia cells: 46.2;Oligodendrocytes: 66.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 5.8;RT4: 6.1;TIME: 13.5;U-266/70: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051291 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA051291: AB_2681423" "unprognostic (4.31e-2)" "unprognostic (5.31e-1)" "unprognostic (4.99e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "unprognostic (6.17e-2)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.41e-1)" "unprognostic (6.39e-3)" "unprognostic (3.28e-1)" "unprognostic (9.32e-2)" "unprognostic (1.76e-1)" "unprognostic (1.71e-1)" "unprognostic (5.20e-3)" "unprognostic (1.50e-4)" 4.4 7.1 8.5 2.3 10.6 1.0 3.9 26.7 9.9 5.2 3.4 2.8 1.8 3.3 1.8 2.5 3.7 4.0 16.5 9.5 7.4 8.5 2.5 3.0 3.9 6.8 7.2 5.8 2.4 0.4 8.5 2.3 7.1 3.2 1.6 7.7 2.1 1.5 1.9 2.1 2.9 2.4 5.2 4.2 3.5 6.5 8.3 3.9 9.2 1.6 2.9 3.3 4.7 12.6 0.3 0.3 1.4 0.0 0.8 1.1 0.9 0.3 0.4 0.1 0.2 0.5 5.3 1.3 2.8 0.0 0.0 0.1 0.3 2.5 0.2 1.4 0.6 0.6 1.1 0.0 0.3 0.0 1.0 1.0 0.2 0.6 0.0 2.2 5.8 3.7 0.2 1.1 0.2 0.0 3.0 0.8 2.4 0.0 0.8 2.4 0.0 0.0 0.9 6.1 1.6 0.9 0.3 0.0 0.5 3.8 0.0 0.5 13.5 0.4 0.3 0.0 0.4 7.9 4.7 0.0 5.0 0.1 0.6 0.0 0.0 0.5 0.2 0.0 0.2 0.0 0.9 0.3 0.0 0.0 0.9 0.5 0.0 0.7 0.0 0.4 0.4 0.2 8.5 10.6 26.7 9.9 9.5 7.4 6.8 7.2 7.1 5.2 8.3 12.6 13.3 0.0 2.2 20.2 1.9 1.1 1.7 1.4 1.2 15.6 1.8 1.5 36.4 1.5 1.4 7.3 22.9 0.6 5.6 0.5 1.9 0.8 44.1 7.1 1.8 14.1 15.6 2.7 91.9 0.9 0.1 3.9 9.2 7.1 1.3 6.6 24.7 3.7 0.6 5.0 56.1 1.0 0.0 1.3 1.2 60.7 2.5 0.7 1.8 7.5 1.0 46.2 5.2 30.7 66.4 1.3 0.3 1.9 1.0 0.8 0.5 0.3 2.3 6.6 0.0 3.7 3.9 9.2 8.5 1.8 0.9 0.1 3.2 6.8 1.9 1.2 KLHL4 "DKELCHL, KHL4, KIAA1687" ENSG00000102271 "Kelch like family member 4" Q9C0H6 X 87517409-87670050 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 26.5;brain: 21.3" "Group enriched" "Detected in some" 4 "Oligodendrocytes: 286.2;Theca cells: 109.4" "Cancer enriched" "Detected in some" 8 "glioma: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;GAMG: 18.2;HUVEC TERT2: 32.0;NTERA-2: 24.3;SuSa: 17.8;TIME: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029192 Approved Supported "Microtubules,Centriolar satellite" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Microtubules "Centriolar satellite" "HPA029192: AB_10602341" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (8.74e-2)" "unprognostic (2.84e-3)" "unprognostic (1.48e-2)" "unprognostic (5.90e-2)" "unprognostic (1.71e-2)" "unprognostic (1.89e-2)" "unprognostic (5.21e-2)" "unprognostic (2.63e-1)" "unprognostic (5.98e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (8.08e-5)" "unprognostic (2.40e-4)" "unprognostic (1.05e-1)" "unprognostic (5.87e-2)" "unprognostic (7.25e-4)" 1.3 26.5 5.3 0.4 10.2 0.0 0.9 7.3 7.1 1.2 0.6 0.3 0.1 3.0 0.3 0.5 2.5 1.5 0.8 5.2 5.7 1.1 0.6 0.8 0.4 9.6 7.5 7.9 0.3 0.0 0.0 0.1 9.5 0.3 0.3 2.3 0.0 1.4 0.3 0.1 0.3 5.1 7.5 1.3 0.3 7.0 6.7 0.1 0.6 0.3 0.1 0.9 0.2 21.3 0.0 3.6 14.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 18.2 0.0 0.1 0.9 0.0 1.4 0.4 0.0 2.6 0.0 11.0 0.2 0.0 1.6 4.7 6.0 1.3 11.6 32.0 0.0 0.2 2.5 8.1 0.0 0.0 0.0 24.3 0.1 5.7 0.0 8.9 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 17.8 0.0 0.1 34.4 0.0 5.6 0.0 0.5 0.2 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 10.2 7.3 7.1 5.2 5.7 9.6 7.5 9.5 7.5 6.7 21.3 1.7 0.0 0.0 2.0 0.0 0.1 0.0 0.1 0.0 3.6 0.0 0.0 1.5 0.0 0.0 0.0 8.4 0.0 0.2 0.0 0.0 0.0 0.7 0.2 0.1 15.0 0.0 0.0 44.4 0.0 0.0 4.4 0.0 0.1 0.0 4.5 14.3 0.2 0.1 0.0 6.6 0.0 0.0 0.3 0.3 1.5 0.9 0.1 0.0 4.7 0.0 1.5 0.0 36.2 286.2 0.1 0.0 1.5 0.1 0.0 0.0 3.4 2.2 4.1 0.0 1.2 0.5 0.4 0.4 0.0 0.3 0.0 0.7 109.4 0.0 0.0 KSR2 FLJ25965 ENSG00000171435 "Kinase suppressor of ras 2" Q6VAB6 12 117453012-117968990 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.0;pituitary gland: 7.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 161.8;Excitatory neurons: 284.7;Inhibitory neurons: 234.9;Oligodendrocyte precursor cells: 95.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 10.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 4.5;SCLC-21H: 3.2;TIME: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035536 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA035536: AB_10673485" "unprognostic (1.74e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (2.29e-2)" "unprognostic (9.11e-2)" "unprognostic (8.42e-2)" "unprognostic (6.91e-3)" "unprognostic (1.10e-2)" "unprognostic (5.78e-2)" "unprognostic (5.80e-2)" "unprognostic (2.05e-4)" "unprognostic (1.19e-1)" "unprognostic (9.28e-3)" "unprognostic (5.02e-2)" "unprognostic (5.68e-2)" "unprognostic (8.14e-3)" "unprognostic (5.74e-2)" 0.0 0.9 2.3 0.0 2.4 0.0 0.2 1.1 10.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.2 0.0 0.0 7.7 0.0 0.7 0.0 0.0 0.1 0.7 0.0 0.0 0.5 0.6 7.9 0.0 0.6 0.1 0.3 1.9 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.8 0.3 0.0 0.6 0.0 0.1 0.2 0.0 2.7 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 1.3 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.1 0.4 0.9 3.2 0.1 0.0 0.0 0.0 0.0 0.7 0.0 6.9 0.0 0.5 0.0 0.1 0.5 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.4 1.1 10.0 7.7 0.0 0.7 0.0 0.6 0.1 0.3 2.7 0.9 0.0 0.0 17.6 0.5 0.3 1.2 0.1 0.0 55.2 2.8 2.4 2.2 5.7 0.2 161.8 39.6 0.9 0.0 1.3 0.0 2.3 10.8 4.0 0.3 0.5 20.4 5.3 284.7 1.5 0.4 0.1 0.0 4.7 0.0 0.0 0.0 0.0 0.1 47.1 234.9 10.3 2.0 0.3 0.4 12.5 0.0 0.0 0.0 5.6 0.0 2.4 0.0 95.0 4.2 0.4 1.5 0.0 0.0 1.4 0.1 0.8 0.3 28.2 0.0 0.3 0.1 0.6 3.1 0.0 0.3 0.3 0.6 0.0 3.0 1.3 KTN1 "CG1, KIAA0004, KNT" ENSG00000126777 "Kinectin 1" Q86UP2 14 55559072-55701526 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003178, CAB015331, HPA017876" Enhanced Enhanced "Endoplasmic reticulum" NA NA 55000 "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Endoplasmic reticulum" "CAB015331: , HPA003178: AB_1079218, HPA017876: AB_1852652" "unprognostic (7.00e-3)" "unprognostic (2.99e-2)" "unprognostic (8.60e-2)" "unprognostic (5.50e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.83e-5)" "prognostic unfavorable (3.76e-4)" "unprognostic (1.75e-1)" "unprognostic (1.21e-2)" "unprognostic (1.01e-1)" "unprognostic (9.08e-2)" "unprognostic (8.72e-2)" "prognostic favorable (1.01e-6)" "unprognostic (1.27e-1)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" 81.6 77.7 90.8 52.8 98.9 36.1 81.6 92.8 106.3 61.4 165.0 97.4 43.4 58.1 97.1 72.7 53.2 58.6 134.6 81.0 94.2 104.0 106.6 67.0 61.8 100.2 95.3 63.9 67.2 143.0 67.4 69.4 100.7 77.5 90.8 127.9 73.5 73.5 378.2 137.6 53.2 60.3 95.2 53.4 61.1 145.1 99.4 54.7 107.7 281.6 61.0 113.1 55.2 110.3 200.5 133.4 100.3 106.5 132.8 127.3 140.2 159.7 127.3 97.2 85.2 89.4 233.9 152.8 213.4 166.7 102.7 347.2 122.5 138.2 162.7 251.9 65.2 109.1 223.0 174.4 126.3 160.3 83.3 119.1 124.6 122.1 208.4 208.3 161.9 122.2 107.4 88.1 189.0 154.6 141.3 95.0 76.8 91.1 194.3 109.6 258.2 73.5 244.8 307.0 122.4 100.0 245.8 113.2 143.2 201.7 115.3 101.7 230.0 193.9 250.4 100.0 151.2 38.9 55.9 110.4 229.4 93.4 109.5 117.0 42.7 48.0 56.2 40.3 54.7 95.6 69.4 65.8 44.0 106.6 71.1 62.1 29.6 64.9 52.6 185.8 48.4 16.0 90.8 98.9 92.8 106.3 81.0 94.2 100.2 95.3 100.7 95.2 99.4 110.3 363.1 307.7 239.8 72.5 171.7 654.5 285.8 215.6 270.9 206.5 460.6 348.7 852.7 270.2 214.7 428.6 360.7 155.1 194.9 575.2 31.3 249.7 721.9 351.3 186.6 345.0 224.0 165.3 93.9 304.0 199.1 211.9 95.3 298.1 134.9 384.5 295.9 401.7 116.8 326.4 112.1 226.4 207.5 181.3 261.6 377.9 248.5 168.9 172.5 104.9 194.3 449.2 142.2 90.0 139.8 341.2 325.7 441.6 184.6 283.5 152.6 109.3 319.3 400.9 335.2 333.5 292.1 694.3 386.4 217.8 723.0 164.7 168.3 162.4 282.4 328.0 L3MBTL3 KIAA1798 ENSG00000198945 "L3MBTL histone methyl-lysine binding protein 3" Q96JM7 6 130013699-130141449 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 63.5;HUVEC TERT2: 62.5;TIME: 43.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044382, HPA053035" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 34: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA044382: AB_2678920, HPA053035: AB_2682021" "unprognostic (2.33e-1)" "unprognostic (9.92e-2)" "unprognostic (1.40e-1)" "unprognostic (7.82e-2)" "unprognostic (4.22e-3)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (1.48e-2)" "unprognostic (2.90e-1)" "unprognostic (2.63e-1)" "unprognostic (7.56e-3)" "unprognostic (1.07e-1)" "unprognostic (8.44e-2)" "unprognostic (3.94e-3)" "unprognostic (2.88e-1)" "unprognostic (2.45e-2)" "unprognostic (1.60e-2)" 4.5 11.0 3.3 9.9 3.3 7.7 4.7 1.7 3.6 9.5 9.6 4.6 2.8 11.2 11.7 2.3 5.5 5.3 2.4 4.1 3.8 4.8 5.8 4.0 11.1 2.5 3.1 10.1 2.3 5.6 5.5 5.7 2.4 7.0 5.0 2.1 4.9 6.2 2.5 2.7 5.1 8.3 2.5 12.6 3.3 7.6 4.5 7.7 6.0 2.1 8.9 5.7 5.3 2.6 1.7 6.5 15.2 2.4 10.4 13.4 3.1 7.8 15.9 3.0 5.5 8.0 8.1 2.7 11.0 9.9 9.3 6.5 8.7 13.6 4.6 6.1 8.8 18.3 3.2 2.0 5.2 10.8 63.5 8.8 9.6 3.6 10.2 15.1 62.5 8.3 13.3 7.1 7.7 0.7 23.2 1.9 7.0 1.7 3.3 8.7 4.2 0.0 9.8 2.5 0.5 2.0 2.9 0.7 6.1 18.2 16.4 9.3 43.0 5.1 6.9 0.9 5.3 1.4 0.1 4.7 2.5 4.5 5.2 8.2 4.9 4.8 3.7 5.5 3.2 10.7 3.5 4.7 1.9 13.4 3.2 4.1 4.9 2.1 22.7 14.8 5.9 1.0 3.3 3.3 1.7 3.6 4.1 3.8 2.5 3.1 2.4 2.5 4.5 2.6 9.1 3.2 6.5 6.5 20.5 5.1 5.1 2.4 10.2 4.2 5.3 2.8 3.9 1.5 3.8 9.2 2.1 13.4 20.7 2.8 1.9 5.6 24.2 6.1 12.8 9.4 3.6 5.0 20.8 5.4 7.1 7.3 4.6 16.1 40.4 24.7 8.9 6.3 4.0 0.0 10.5 9.3 6.1 8.2 4.0 3.1 9.6 9.5 1.8 11.2 12.9 5.3 13.4 15.6 8.5 10.9 5.2 6.0 5.2 4.7 0.5 5.9 4.1 0.7 6.6 11.2 8.6 5.8 7.6 4.0 4.4 6.2 15.6 9.5 5.0 5.5 LACC1 "C13orf31, FAMIN, FLJ38725" ENSG00000179630 "Laccase domain containing 1" Q8IV20 13 43879284-43893932 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.4" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 39.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.0;eosinophil: 3.1;intermediate monocyte: 5.2;myeloid DC: 2.7;non-classical monocyte: 8.0" "Group enriched" "Detected in many" 4 "dendritic cells: 2.7;granulocytes: 3.1;monocytes: 8.0" "Cell line enhanced" "Detected in many" "HMC-1: 37.1;TIME: 118.2" "Low region specificity" "Detected in all" "CAB034228, HPA040150, HPA044211" Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB034228: AB_1564163, HPA040150: AB_10963540, HPA044211: AB_10961258" "unprognostic (2.48e-1)" "unprognostic (3.27e-2)" "unprognostic (4.54e-2)" "unprognostic (3.31e-3)" "unprognostic (1.17e-2)" "unprognostic (3.90e-2)" "unprognostic (6.41e-3)" "unprognostic (4.43e-2)" "unprognostic (3.03e-3)" "unprognostic (1.78e-2)" "unprognostic (6.06e-3)" "unprognostic (2.02e-1)" "unprognostic (3.93e-2)" "unprognostic (3.30e-1)" "unprognostic (9.36e-3)" "unprognostic (2.22e-1)" "unprognostic (1.18e-1)" 6.4 6.6 12.7 12.2 22.3 1.9 5.4 10.8 20.6 4.5 6.8 10.3 9.9 3.9 3.2 6.8 3.2 9.8 10.1 11.7 13.6 4.8 7.2 6.4 8.8 13.9 14.5 3.4 3.5 9.9 2.8 6.1 15.2 5.4 13.3 0.8 4.6 4.9 1.4 4.8 13.8 5.8 12.5 7.2 6.8 9.4 17.3 6.5 3.5 1.2 8.3 11.1 2.9 27.4 4.7 2.5 1.3 0.0 2.7 12.3 9.5 10.3 25.7 2.8 3.9 5.3 10.5 9.9 2.3 13.8 6.0 6.7 0.3 2.9 4.5 6.6 1.7 12.3 2.6 1.9 12.5 2.9 37.1 16.3 8.5 10.3 12.6 3.4 5.9 1.1 0.0 7.1 6.4 2.3 0.3 3.7 0.9 2.6 2.2 2.3 0.0 5.2 7.4 5.5 1.6 2.5 3.4 1.2 4.9 6.8 1.5 6.2 118.2 3.5 1.1 18.8 0.1 0.0 0.0 2.4 10.0 3.7 8.0 1.0 3.0 3.1 0.7 5.2 0.8 0.8 0.6 0.6 2.7 1.0 0.2 0.3 0.1 0.4 8.0 0.5 0.8 1.0 12.7 22.3 10.8 20.6 11.7 13.6 13.9 14.5 15.2 12.5 17.3 27.4 4.6 12.8 6.8 1.0 5.9 5.7 8.4 8.1 3.4 0.5 5.1 4.6 24.2 4.3 7.8 11.0 0.0 6.5 1.0 7.6 1.9 5.5 1.3 5.1 3.4 7.4 5.4 1.7 2.1 3.8 4.3 4.5 2.0 8.5 8.2 9.7 5.0 5.1 15.3 0.0 6.2 4.4 6.1 17.6 10.3 3.1 2.1 24.2 1.8 1.9 7.8 2.0 1.0 2.0 39.2 8.0 11.2 1.5 0.5 11.4 10.5 8.2 7.2 0.2 6.6 5.3 6.0 17.1 16.7 8.4 10.2 9.2 4.3 4.6 6.7 10.2 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LAMA5 ENSG00000130702 "Laminin subunit alpha 5" O15230 20 62307955-62367312 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Cytotrophoblasts: 104.4;Glandular and luminal cells: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 114.9;CACO-2: 159.6;EFO-21: 114.4;HaCaT: 107.2;HeLa: 118.3;TIME: 138.4" "Low region specificity" "Detected in many" "HPA058389, CAB078157" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 1800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "CAB078157: AB_2665809, HPA058389: " "unprognostic (8.01e-2)" "unprognostic (2.47e-1)" "unprognostic (1.92e-2)" "unprognostic (3.42e-3)" "unprognostic (1.17e-1)" "unprognostic (9.90e-3)" "unprognostic (4.01e-3)" "unprognostic (5.45e-2)" "unprognostic (8.99e-2)" "unprognostic (1.34e-2)" "unprognostic (5.98e-3)" "unprognostic (2.98e-3)" "unprognostic (4.04e-2)" "unprognostic (9.86e-3)" "unprognostic (2.07e-1)" "unprognostic (9.76e-2)" "unprognostic (1.33e-2)" 27.1 11.8 4.7 5.0 2.2 1.3 27.0 15.2 7.0 26.3 18.9 66.7 5.3 31.3 1.2 24.5 31.8 7.9 26.6 2.4 2.0 32.7 13.2 43.9 3.0 3.2 1.9 9.3 13.9 4.8 12.1 20.0 2.5 36.7 1.2 0.6 17.8 15.4 11.0 36.0 19.9 7.3 0.6 14.0 25.1 4.6 9.3 2.7 28.6 2.8 1.9 32.6 30.2 0.4 15.1 114.9 2.2 14.8 2.7 31.0 85.9 4.2 2.2 3.3 0.6 159.6 59.1 1.3 114.4 0.1 3.6 107.2 3.1 45.8 0.2 0.3 6.5 3.8 118.3 46.1 9.9 0.0 16.6 1.6 29.6 7.9 8.0 5.7 15.0 0.0 7.0 1.7 0.0 22.3 0.1 0.4 7.3 19.3 65.9 0.2 1.4 12.8 28.6 70.3 1.1 44.5 63.2 62.2 1.2 11.6 62.0 0.9 138.4 1.6 41.2 0.7 18.9 0.8 0.2 0.6 31.7 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 2.2 15.2 7.0 2.4 2.0 3.2 1.9 2.5 0.6 9.3 0.4 60.2 76.9 37.1 19.9 6.9 17.1 16.0 56.8 52.9 3.6 16.7 20.8 20.5 12.8 43.9 38.6 8.4 104.4 3.9 0.6 0.0 28.6 4.3 35.5 11.7 49.6 2.4 6.1 5.9 4.5 23.3 13.0 6.1 82.0 2.5 0.9 18.9 12.7 13.1 3.3 12.7 0.3 14.2 0.6 5.4 1.3 9.9 2.2 1.8 10.3 1.1 8.2 1.0 3.5 1.3 13.2 0.1 19.5 8.5 21.9 0.0 12.2 49.6 1.8 26.3 11.0 39.4 0.6 1.7 23.4 12.6 57.3 2.2 1.7 0.6 27.5 LAMB1 CLM ENSG00000091136 "Laminin subunit beta 1" P07942 7 107923799-108003213 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 185.6;Fibroblasts: 99.6;Peritubular cells: 141.8;Theca cells: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 593.0;ASC TERT1: 815.3;HSkMC: 779.6;TIME: 547.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004056, HPA004132, CAB004256" Enhanced "Secreted to extracellular matrix" NA NA 250000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "CAB004256: AB_627867, HPA004056: AB_1079226, HPA004132: AB_1079225" "unprognostic (2.39e-1)" "unprognostic (6.45e-3)" "unprognostic (2.01e-1)" "unprognostic (6.75e-2)" "unprognostic (3.45e-3)" "unprognostic (8.26e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (3.77e-2)" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "unprognostic (3.44e-1)" "unprognostic (5.01e-2)" "unprognostic (2.87e-2)" "unprognostic (4.50e-3)" "unprognostic (1.75e-1)" "unprognostic (4.45e-2)" "unprognostic (1.46e-1)" 141.4 21.8 1.2 26.5 1.6 0.1 74.1 0.9 1.7 46.4 23.0 87.0 29.3 78.9 3.3 25.2 44.1 53.4 53.9 2.4 0.7 81.4 14.7 104.3 9.4 0.0 0.8 29.4 48.2 12.1 11.8 154.3 0.2 18.1 40.4 0.7 24.6 29.7 20.4 39.3 67.5 73.2 0.1 42.4 49.5 11.4 1.4 19.7 43.5 40.6 5.2 53.5 31.0 0.4 94.5 148.6 77.3 3.6 593.0 815.3 291.9 103.5 182.5 68.6 72.1 306.7 166.6 0.0 127.7 200.3 90.8 41.9 24.8 143.6 49.9 0.1 24.8 4.8 52.6 87.9 364.3 0.0 2.8 779.6 49.0 175.9 193.4 409.2 450.0 2.8 17.0 0.0 126.5 29.9 0.1 0.5 42.9 54.9 103.6 0.4 51.9 0.3 238.5 96.0 24.3 142.1 75.1 100.9 68.5 180.2 37.6 1.1 547.1 179.9 44.3 60.2 133.1 0.0 0.2 0.4 89.9 0.0 301.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.9 1.7 2.4 0.7 0.0 0.8 0.2 0.1 1.4 0.4 81.8 0.0 5.6 2.9 2.2 8.9 5.2 16.7 10.8 12.1 2.0 9.5 16.3 15.7 7.6 27.6 4.2 85.5 3.5 10.5 3.9 18.0 2.0 22.6 185.6 57.8 19.2 0.0 51.6 11.2 27.1 99.6 2.6 34.6 2.5 2.9 20.7 3.5 10.1 8.4 23.7 8.0 8.2 2.8 3.8 4.7 71.1 2.4 8.8 11.2 2.0 2.1 5.2 6.0 3.2 21.6 17.0 141.8 0.4 3.6 9.5 11.6 2.9 8.6 52.6 10.2 54.4 5.5 5.1 4.7 6.7 32.6 3.2 174.7 19.2 2.1 LATS2 ENSG00000150457 "Large tumor suppressor kinase 2" Q9NRM7 13 20973036-21061586 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 139.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039191, HPA049037" Approved Supported "Centriolar satellite,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Centriolar satellite, Cytosol" "HPA039191: AB_2676385, HPA049037: AB_2680609" "unprognostic (2.77e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (6.22e-3)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (1.84e-2)" "unprognostic (1.88e-1)" "unprognostic (2.16e-3)" "unprognostic (4.48e-1)" "unprognostic (6.57e-3)" "unprognostic (8.03e-2)" "unprognostic (4.92e-2)" "unprognostic (7.85e-2)" "unprognostic (1.66e-2)" "unprognostic (1.25e-1)" "unprognostic (7.97e-2)" "unprognostic (1.11e-2)" 19.8 12.2 3.9 7.3 4.3 15.1 12.4 4.8 3.7 10.1 7.7 13.1 2.9 12.2 3.0 11.5 9.7 15.1 11.5 5.3 3.3 9.9 9.8 12.4 5.3 5.4 4.6 11.0 10.2 4.3 2.3 13.9 4.5 9.8 4.3 1.3 6.1 8.8 16.7 7.7 6.2 13.1 4.1 11.2 7.8 14.6 5.1 2.4 13.5 13.3 3.3 14.2 8.9 4.7 6.8 7.4 16.0 9.7 18.4 24.1 14.6 22.1 22.8 22.5 19.2 21.1 10.0 0.0 10.5 33.8 8.8 9.6 9.5 10.1 33.1 3.8 2.5 12.4 9.4 16.0 28.6 3.4 4.2 36.0 18.1 14.9 9.9 11.3 32.0 2.8 2.3 0.5 28.9 11.7 0.4 11.6 3.8 7.0 3.5 2.9 28.5 0.0 16.3 3.1 0.3 0.0 17.4 11.3 23.9 13.9 9.8 6.4 40.6 23.8 15.9 17.7 14.1 2.9 1.7 0.0 5.7 3.8 18.6 0.1 0.5 0.5 0.4 0.4 0.9 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.9 0.4 0.2 0.0 0.0 0.1 3.9 4.3 4.8 3.7 5.3 3.3 5.4 4.6 4.5 4.1 5.1 4.7 36.6 41.7 9.9 12.1 2.8 32.9 14.7 8.5 21.6 0.4 12.5 11.0 24.3 15.7 10.5 5.5 0.0 24.8 21.0 6.5 3.9 10.1 139.4 40.3 30.4 35.1 0.0 8.2 0.6 7.3 8.9 37.2 8.6 62.1 5.1 9.8 44.6 19.6 9.9 0.0 0.6 1.9 6.1 17.9 49.3 13.7 25.4 26.0 17.8 21.5 11.0 4.9 13.4 2.0 8.8 18.6 2.8 34.6 8.9 21.7 0.6 9.5 11.6 1.0 6.6 32.3 30.0 8.8 14.5 9.9 25.3 48.0 8.1 7.9 1.5 15.2 LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 236.5;Endothelial cells: 194.4;Excitatory neurons: 1314.4;Hepatic stellate cells: 364.8;Inhibitory neurons: 196.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cell line enhanced" "Detected in many" "AF22: 18.3;fHDF/TERT166: 19.0;HAP1: 34.4;HUVEC TERT2: 65.3;TIME: 17.1;U-138 MG: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" 58.9 15.5 13.7 8.0 19.8 0.4 52.2 3.3 45.9 43.5 7.6 12.7 6.5 65.5 23.4 15.8 28.0 31.2 33.7 23.3 7.3 28.0 26.0 58.2 11.5 4.4 10.9 18.2 7.6 17.0 9.0 58.8 4.7 18.0 8.5 5.3 10.8 13.7 14.0 9.4 12.8 53.8 7.1 50.4 11.5 5.0 7.9 8.3 31.3 24.3 4.8 22.5 22.8 19.7 0.0 0.0 18.3 0.1 10.5 16.9 0.0 10.2 8.0 1.2 2.7 0.0 0.0 0.0 0.0 19.0 0.0 0.0 34.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 9.5 0.0 12.5 0.0 2.7 65.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.7 0.0 0.1 8.8 0.0 0.0 0.8 0.0 0.0 2.3 0.0 0.0 0.0 4.9 0.0 0.0 17.1 25.7 0.1 1.2 0.0 8.3 0.1 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.2 13.7 19.8 3.3 45.9 23.3 7.3 4.4 10.9 4.7 7.1 7.9 19.7 236.5 0.0 5.5 44.7 1.5 8.7 0.3 0.0 2.8 27.1 1.7 2.2 8.7 2.8 0.0 0.0 0.0 0.2 6.8 0.0 0.0 4.4 1.3 1.4 36.5 194.4 0.0 8.0 1314.4 0.2 0.2 44.4 4.1 1.1 5.7 0.1 364.8 3.1 0.4 0.0 196.5 0.0 0.0 16.4 13.2 2.6 38.2 1.4 8.8 117.1 0.0 10.4 3.1 120.6 36.7 0.2 0.0 50.4 0.0 0.3 0.0 0.1 0.7 2.1 6.6 2.8 19.3 0.2 0.7 1.3 6.8 0.1 4.9 39.7 0.0 0.5 LDLRAD2 ENSG00000187942 "Low density lipoprotein receptor class A domain containing 2" Q5SZI1 1 21812265-21825225 "Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.2;Granulosa cells: 4.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 1.2;THP-1: 1.0;TIME: 2.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "basal ganglia: 4.0;midbrain: 5.9" HPA030478 Approved "Secreted - unknown location" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "HPA030478: AB_10601541" "unprognostic (4.16e-2)" "unprognostic (1.22e-1)" "unprognostic (4.13e-2)" "unprognostic (4.21e-2)" "unprognostic (1.78e-1)" "unprognostic (6.22e-3)" "unprognostic (1.35e-2)" "unprognostic (4.85e-2)" "unprognostic (7.52e-2)" "unprognostic (3.80e-2)" "unprognostic (5.34e-2)" "unprognostic (5.38e-2)" "unprognostic (1.04e-3)" "unprognostic (7.39e-3)" "unprognostic (3.14e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" 3.7 2.8 0.4 0.8 0.3 1.0 3.0 0.2 0.1 2.7 0.4 4.3 1.6 3.5 0.0 1.7 2.7 0.5 6.8 0.7 1.1 2.2 0.7 1.6 0.7 2.4 3.3 1.1 2.0 0.0 1.5 0.1 1.7 3.7 0.1 0.0 7.2 0.0 1.2 1.3 2.4 0.1 1.7 2.7 3.7 1.4 1.4 0.0 2.2 0.0 0.3 3.9 2.4 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.5 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.1 0.1 1.2 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 1.0 2.2 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.3 0.2 0.1 0.7 1.1 2.4 3.3 1.7 1.7 1.4 0.3 2.2 0.0 0.6 0.0 0.6 0.5 0.1 0.4 0.6 0.0 0.1 0.1 0.7 0.0 0.2 1.8 0.0 0.2 0.3 0.0 0.0 0.2 1.7 0.3 1.2 1.6 0.0 1.3 0.2 0.0 0.6 1.3 0.0 0.9 0.0 4.9 0.7 0.2 0.3 0.0 0.1 0.0 0.0 0.3 0.2 0.4 0.0 0.3 0.0 1.0 0.5 0.0 0.0 0.0 0.2 0.3 0.1 0.0 1.3 0.5 0.0 0.0 0.8 0.0 0.0 1.2 0.7 0.6 1.2 0.1 0.4 0.3 0.4 0.4 0.0 0.0 LIPG EDL ENSG00000101670 "Lipase G, endothelial type" Q9Y5X9 18 49560699-49599185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "placenta: 149.3;thyroid gland: 242.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Extravillous trophoblasts: 67.9;Glandular and luminal cells: 49.0;Hepatocytes: 78.2" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 20.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 122.6;HaCaT: 189.8;RPTEC TERT1: 122.4;TIME: 247.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA016966 Uncertain "Secreted to blood" NA NA 657000000 810000 "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA016966: AB_1852893" "unprognostic (2.20e-2)" "unprognostic (3.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.25e-3)" "unprognostic (6.38e-2)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" "unprognostic (4.55e-3)" "unprognostic (9.93e-2)" "unprognostic (1.44e-1)" "unprognostic (6.44e-2)" "unprognostic (8.74e-2)" "unprognostic (2.98e-1)" "unprognostic (8.68e-2)" "unprognostic (5.64e-2)" "unprognostic (1.54e-1)" "unprognostic (1.35e-1)" 4.6 0.2 0.9 16.3 0.6 0.3 1.0 4.0 2.6 0.9 1.7 5.9 6.4 1.4 2.9 1.3 0.5 14.0 1.2 3.2 0.7 6.7 34.7 7.2 1.8 2.8 2.8 0.2 1.9 0.2 0.4 149.3 1.6 1.5 7.2 4.9 0.5 20.9 2.5 1.4 7.2 7.7 1.4 0.4 1.7 7.0 3.7 1.9 242.5 0.1 1.7 14.4 0.6 1.2 2.2 0.3 53.6 122.6 0.5 0.1 0.9 0.6 5.8 0.0 0.1 54.5 19.6 0.2 29.7 0.0 37.2 189.8 8.1 39.0 0.0 0.6 0.3 0.1 0.2 0.3 8.1 0.1 0.8 5.4 43.0 19.1 36.8 0.3 28.0 0.2 0.3 0.3 0.0 0.0 0.0 0.2 8.1 1.4 0.5 0.1 0.0 3.0 122.4 14.8 0.8 0.1 1.0 1.4 0.1 6.9 0.2 0.2 247.4 0.2 0.1 0.1 0.6 0.1 0.0 0.1 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.6 4.0 2.6 3.2 0.7 2.8 2.8 1.6 1.4 3.7 1.2 0.3 0.0 1.1 0.7 0.3 1.8 5.6 3.3 0.0 0.6 2.8 1.9 1.8 24.3 3.5 14.7 60.5 5.5 0.1 9.3 0.0 3.3 8.4 19.1 8.3 7.9 13.8 0.0 0.2 1.4 67.9 6.0 2.6 49.0 0.0 11.5 5.3 78.2 1.8 0.0 0.3 5.3 2.0 1.9 0.0 8.1 0.3 0.8 1.8 2.8 0.7 1.1 0.0 1.0 0.2 12.8 2.7 0.0 0.3 10.6 10.1 1.3 0.5 2.9 0.0 1.0 2.0 1.4 0.9 0.4 2.6 19.4 1.1 0.1 11.2 11.4 LIPT1 "MGC12290, MGC13378" ENSG00000144182 "Lipoyltransferase 1" Q9Y234 2 99154955-99163157 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 41.0;Spermatocytes: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034802 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA034802: AB_10669851" "unprognostic (1.13e-2)" "unprognostic (7.21e-3)" "unprognostic (1.75e-1)" "unprognostic (1.32e-2)" "unprognostic (7.46e-2)" "unprognostic (6.48e-2)" "unprognostic (1.13e-3)" "prognostic favorable (5.70e-4)" "unprognostic (1.49e-2)" "unprognostic (4.11e-2)" "unprognostic (1.82e-2)" "unprognostic (1.59e-1)" "unprognostic (1.32e-3)" "unprognostic (1.72e-1)" "unprognostic (4.92e-2)" "unprognostic (3.16e-1)" "prognostic favorable (9.60e-8)" 7.1 7.8 6.7 6.8 7.5 12.3 10.9 7.4 8.3 8.1 6.3 6.7 8.4 8.1 14.1 5.1 8.1 6.5 8.5 6.9 7.8 11.2 8.1 5.7 10.7 7.2 7.1 11.8 7.3 6.3 6.7 4.9 7.2 9.2 7.3 7.5 8.9 6.0 9.1 7.0 8.4 5.6 7.2 11.9 6.9 13.5 7.2 5.3 11.3 8.9 7.4 6.3 5.6 10.4 6.2 4.0 5.4 9.2 9.3 11.0 13.0 4.0 4.7 3.1 3.4 9.8 10.3 9.9 8.4 2.4 8.4 5.4 6.6 5.0 6.1 10.6 12.0 10.3 5.1 8.7 9.9 7.0 5.1 6.5 8.0 5.6 12.7 6.3 8.8 11.4 10.0 5.8 5.4 5.0 6.9 13.4 13.8 6.0 9.9 11.7 5.8 10.4 10.1 9.2 5.2 5.0 5.6 6.2 14.8 9.8 6.6 14.2 6.4 4.6 6.4 4.1 3.8 9.1 12.9 10.7 4.8 11.4 6.7 15.4 10.3 16.1 16.8 9.6 20.9 14.2 18.9 18.5 5.6 12.4 23.6 19.9 2.7 18.4 9.5 5.6 12.3 11.6 6.7 7.5 7.4 8.3 6.9 7.8 7.2 7.1 7.2 7.2 7.2 10.4 9.3 3.2 6.7 6.5 7.5 3.6 10.8 14.5 6.2 5.2 3.9 7.9 6.6 2.8 8.5 12.9 2.1 7.6 9.7 3.3 13.7 5.1 41.0 3.6 6.5 7.8 6.1 3.2 5.3 3.4 4.3 7.2 3.1 3.4 5.1 8.3 12.8 2.2 7.2 11.8 5.5 6.1 6.1 7.9 2.2 25.4 9.6 4.6 1.8 1.9 8.5 12.1 18.6 9.5 14.3 3.4 6.9 7.5 2.7 5.6 15.9 11.8 9.0 10.6 6.6 13.1 5.8 40.6 12.8 3.0 4.3 5.3 8.9 5.0 6.2 6.2 LIX1L MGC46719 ENSG00000271601 "Limb and CNS expressed 1 like" Q8IVB5 1 145933423-145958017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063598 Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA063598: AB_2685055" "unprognostic (5.21e-2)" "unprognostic (4.09e-1)" "unprognostic (6.84e-3)" "unprognostic (2.85e-2)" "unprognostic (3.71e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (9.81e-2)" "unprognostic (3.46e-1)" "unprognostic (3.87e-2)" "unprognostic (1.84e-3)" "unprognostic (3.51e-2)" "prognostic unfavorable (3.19e-5)" "unprognostic (2.10e-3)" "unprognostic (4.95e-1)" "unprognostic (1.25e-2)" "prognostic unfavorable (5.27e-4)" 21.0 19.0 14.6 15.2 15.1 6.4 16.0 13.8 13.1 27.1 15.6 23.0 6.7 27.6 11.1 9.8 21.1 15.6 16.3 12.9 13.5 9.8 10.2 15.6 20.4 15.0 15.2 36.9 5.8 7.5 16.3 16.2 14.0 16.2 9.2 19.0 9.4 20.8 34.8 8.1 13.3 25.7 13.9 20.8 11.3 6.6 15.8 16.6 10.8 31.5 20.8 21.1 16.9 15.0 7.3 10.3 31.0 34.5 63.4 53.5 0.4 16.3 29.4 24.8 18.1 0.8 6.7 19.6 17.5 33.1 9.3 0.4 14.6 13.6 23.3 18.2 4.5 10.9 11.0 10.4 20.8 26.2 24.8 32.9 6.2 20.3 29.3 39.9 48.7 25.8 16.4 30.6 39.9 0.2 34.6 21.8 9.0 0.1 13.2 23.2 15.6 32.4 25.7 0.2 11.1 31.6 33.5 0.1 24.9 12.8 1.2 20.3 38.0 41.9 11.5 27.6 27.8 24.5 18.7 19.9 29.5 21.4 20.7 4.0 2.2 3.9 5.7 2.2 7.0 3.0 6.6 5.8 2.1 3.1 6.1 8.0 3.7 3.8 3.8 3.3 5.4 2.6 14.6 15.1 13.8 13.1 12.9 13.5 15.0 15.2 14.0 13.9 15.8 15.0 29.7 0.0 5.8 11.1 23.1 11.3 10.6 10.8 11.4 17.1 3.8 7.5 17.5 14.3 4.9 11.0 8.4 1.4 18.6 2.8 3.9 9.6 10.4 2.3 21.6 36.7 12.6 23.5 5.1 10.0 4.3 28.4 2.6 3.5 5.1 10.8 45.7 19.6 21.1 13.5 6.1 1.4 8.2 24.3 43.8 3.6 35.8 18.8 28.4 15.9 27.4 28.1 35.0 8.5 7.0 11.0 1.2 56.4 17.8 7.5 0.1 7.7 3.0 13.6 26.3 16.8 37.9 24.1 4.7 3.1 7.7 0.8 37.4 21.4 2.1 4.2 LMBR1L "FLJ10494, KIAA1174" ENSG00000139636 "Limb development membrane protein 1 like" Q6UX01 12 49097136-49110900 "Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Granulosa cells: 722.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.25e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (1.05e-1)" "unprognostic (1.89e-1)" "unprognostic (2.62e-1)" "unprognostic (6.56e-3)" "unprognostic (1.17e-1)" "unprognostic (1.77e-3)" "unprognostic (1.59e-1)" "prognostic favorable (3.50e-4)" "unprognostic (2.72e-2)" "prognostic unfavorable (4.45e-7)" "unprognostic (2.48e-2)" "unprognostic (1.16e-1)" "unprognostic (1.95e-2)" "unprognostic (1.52e-3)" 6.5 9.4 12.6 4.0 13.0 4.3 4.4 14.8 18.2 6.4 12.3 8.2 6.4 7.6 6.7 8.8 7.2 5.1 11.6 12.8 13.6 10.3 6.2 5.5 7.3 13.3 12.8 8.6 5.9 5.0 8.5 11.0 13.3 6.6 4.5 5.9 5.6 6.9 6.0 5.2 8.8 6.9 12.5 7.5 5.9 25.7 12.7 11.0 3.9 6.1 6.5 8.7 6.2 14.0 7.5 10.5 13.3 13.7 9.3 13.4 14.5 7.0 11.1 9.3 8.5 10.7 5.9 3.2 5.5 14.4 5.9 3.6 9.8 5.0 5.7 12.3 15.6 7.5 6.1 9.8 17.9 5.3 11.7 15.3 6.8 13.3 7.9 25.4 29.5 13.0 19.7 4.9 8.9 3.3 9.3 14.8 6.2 20.1 7.6 6.5 5.5 3.7 6.9 15.1 7.4 6.5 5.9 5.8 13.4 11.7 5.0 7.0 28.6 6.0 3.7 4.0 2.7 8.9 5.9 4.6 8.8 4.8 3.5 24.1 19.7 51.7 12.9 16.4 11.0 17.3 13.2 14.7 14.1 18.8 18.1 15.4 9.6 6.0 21.1 10.1 22.0 17.4 12.6 13.0 14.8 18.2 12.8 13.6 13.3 12.8 13.3 12.5 12.7 14.0 26.5 6.4 20.0 16.6 26.9 15.4 13.0 13.1 23.9 37.0 14.2 10.9 7.5 7.2 9.9 9.2 20.9 14.8 29.9 15.0 3.9 16.1 104.8 6.1 11.1 27.6 47.1 11.6 14.9 10.2 39.3 21.1 9.7 9.0 17.7 722.7 17.9 8.6 16.7 32.0 14.8 12.5 16.2 13.2 41.5 156.3 13.7 23.4 21.4 14.0 27.6 9.3 27.8 8.5 13.0 17.5 15.5 6.8 36.3 14.0 51.2 3.4 6.8 31.1 13.1 17.6 24.1 14.7 12.5 15.0 14.8 22.3 33.0 18.2 13.2 18.3 LRRC36 FLJ11004 ENSG00000159708 "Leucine rich repeat containing 36" Q1X8D7 16 67326798-67385204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 35.3" "Group enriched" "Detected in some" 7 "Alveolar cells type 2: 94.7;Early spermatids: 192.8;Late spermatids: 118.0;Spermatocytes: 68.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "plasmacytoid DC: 9.7" "Lineage enriched" "Detected in many" 7 "dendritic cells: 9.7" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 1.4;JURKAT: 1.3;TIME: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA058479 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 83: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "HPA058479: AB_2683728" "unprognostic (4.59e-2)" "unprognostic (6.84e-2)" "unprognostic (2.17e-2)" "unprognostic (2.26e-5)" "unprognostic (5.27e-2)" "unprognostic (4.32e-2)" "unprognostic (5.29e-2)" "unprognostic (3.26e-2)" "unprognostic (1.99e-2)" "unprognostic (1.65e-1)" "unprognostic (3.32e-3)" "unprognostic (4.49e-2)" "unprognostic (1.36e-1)" "unprognostic (1.26e-1)" "unprognostic (3.70e-1)" "unprognostic (1.99e-1)" "unprognostic (3.88e-2)" 0.1 0.0 0.2 0.0 0.3 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 3.0 0.1 0.0 0.1 0.4 0.3 0.0 4.9 0.2 0.4 0.3 0.1 0.3 0.0 0.1 6.1 0.3 0.0 0.5 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 35.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.2 0.3 0.2 0.2 0.1 0.4 0.4 0.3 0.3 0.1 0.2 0.0 0.4 3.2 94.7 0.0 0.3 0.3 0.4 0.2 0.0 0.8 0.3 0.3 0.7 0.0 0.8 0.0 0.0 0.1 6.7 0.5 0.0 1.9 192.8 15.4 0.2 3.2 2.4 0.0 1.2 0.0 0.1 1.4 0.0 0.4 8.8 1.5 0.0 0.0 0.2 0.0 2.6 0.6 0.0 0.0 0.7 118.0 2.1 0.7 7.2 1.9 0.7 1.5 0.0 2.0 0.4 0.1 0.3 1.5 0.0 0.1 0.5 1.3 12.0 0.2 0.0 0.7 0.4 68.2 15.1 0.0 0.3 0.3 0.3 0.6 1.7 0.3 LRRC70 "LOC100130733, SLRN" ENSG00000186105 "Leucine rich repeat containing 70" Q7Z2Q7 5 62578819-62581446 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 3.6;Endothelial cells: 4.9;Erythroid cells: 1.7;Fibroblasts: 1.8;granulocytes: 3.8;Hepatic stellate cells: 3.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "HUVEC TERT2: 17.6;TIME: 9.6" "Low region specificity" "Detected in all" HPA013409 Uncertain NA NA 17000 "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013409: AB_10601911" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (4.04e-1)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.17e-4)" "unprognostic (3.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.60e-1)" "unprognostic (2.19e-1)" "unprognostic (4.15e-1)" "unprognostic (7.40e-4)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" 4.7 0.8 0.5 1.4 0.4 3.6 4.7 0.5 1.2 3.9 0.6 1.4 0.8 1.9 1.0 1.7 3.3 3.6 1.8 0.4 0.4 1.9 1.4 1.9 1.9 0.7 0.8 2.9 0.9 1.2 1.4 4.6 0.6 2.0 1.4 1.0 1.2 0.5 0.7 2.7 1.4 3.4 0.6 4.1 1.1 1.7 0.5 1.0 4.0 0.6 0.7 1.7 2.8 0.8 0.2 0.0 0.2 0.1 0.5 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 17.6 0.3 0.2 0.7 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 9.6 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.5 0.4 0.5 1.2 0.4 0.4 0.7 0.8 0.6 0.6 0.5 0.8 3.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.1 0.1 4.9 0.0 1.7 0.0 0.0 0.0 1.8 0.0 0.1 3.8 0.1 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.4 0.3 0.0 0.3 0.0 0.0 0.0 LRRC71 "C1orf92, FLJ32884" ENSG00000160838 "Leucine rich repeat containing 71" Q8N4P6 1 156920632-156933094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.8;fallopian tube: 12.4;testis: 25.4" "Group enriched" "Detected in some" 4 "Early spermatids: 236.9;Late spermatids: 605.3" "Cancer enriched" "Detected in single" 7 "endometrial cancer: 3.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 3.5;PC-3: 1.6;TIME: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (8.91e-2)" "unprognostic (4.21e-2)" "unprognostic (6.13e-2)" "unprognostic (1.95e-3)" "unprognostic (5.43e-2)" "unprognostic (3.98e-2)" "unprognostic (1.28e-1)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (8.02e-2)" "unprognostic (5.07e-3)" "unprognostic (5.18e-1)" "unprognostic (1.68e-7)" "unprognostic (2.29e-1)" "unprognostic (5.18e-2)" "unprognostic (1.23e-1)" "unprognostic (1.56e-2)" 0.2 0.5 0.9 0.0 0.5 0.0 0.1 0.3 0.1 1.0 8.8 0.0 0.0 0.2 0.0 0.0 12.4 0.0 0.1 1.1 1.3 0.1 0.0 2.3 0.0 3.9 4.8 0.1 0.0 0.0 0.1 0.1 2.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.0 25.4 1.1 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.3 0.1 1.1 1.3 3.9 4.8 2.4 3.9 1.1 1.0 0.2 0.0 1.8 0.7 0.0 0.0 0.0 3.1 0.0 0.5 0.0 0.0 0.7 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 236.9 37.8 0.3 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 2.0 0.0 0.0 605.3 4.4 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 3.4 0.0 0.1 0.0 0.0 89.6 0.6 0.0 0.0 1.1 54.2 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 LRRC8A "FLJ10337, KIAA1437, LRRC8, SWELL1" ENSG00000136802 "Leucine rich repeat containing 8 VRAC subunit A" Q8IWT6 9 128882133-128918039 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 192.0;Prostatic glandular cells: 207.0;Urothelial cells: 328.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 163.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (6.33e-2)" "unprognostic (3.88e-2)" "unprognostic (1.88e-3)" "unprognostic (2.61e-2)" "unprognostic (1.72e-1)" "unprognostic (4.38e-3)" "unprognostic (4.29e-2)" "unprognostic (1.19e-3)" "unprognostic (2.44e-1)" "unprognostic (4.80e-2)" "prognostic unfavorable (3.83e-4)" "unprognostic (3.53e-1)" "prognostic favorable (5.27e-5)" "unprognostic (3.69e-1)" "unprognostic (8.77e-2)" "unprognostic (3.93e-3)" "unprognostic (1.02e-2)" 31.4 17.4 68.2 16.2 69.4 17.3 27.3 69.4 77.1 30.8 44.6 31.4 9.7 36.3 7.3 71.7 23.5 23.3 32.0 57.2 67.9 18.2 28.9 42.4 9.3 76.7 77.2 18.8 21.2 32.4 13.7 23.1 67.9 29.3 8.5 13.4 28.1 25.5 13.9 35.2 17.3 29.1 63.9 16.2 25.0 11.8 82.6 9.9 25.6 18.4 10.1 32.7 44.2 52.4 35.1 54.2 32.0 27.5 73.6 28.3 40.4 39.8 26.2 24.1 17.1 24.1 73.2 12.8 43.6 43.3 30.1 163.8 19.9 87.5 11.3 13.1 16.4 11.5 33.4 29.2 49.8 13.8 20.3 22.1 60.9 42.7 50.8 48.6 84.1 17.5 25.8 12.4 31.8 30.3 15.6 13.2 95.9 58.3 58.4 21.4 37.0 20.6 37.9 17.3 19.2 39.9 44.4 27.3 15.8 23.9 19.9 10.2 149.4 69.9 30.2 29.9 58.8 14.4 36.5 15.5 38.7 10.3 41.3 0.7 0.7 1.9 3.9 1.1 1.8 1.2 1.9 2.5 1.0 0.9 1.9 1.8 1.4 3.5 0.3 1.6 3.5 1.0 68.2 69.4 69.4 77.1 57.2 67.9 76.7 77.2 67.9 63.9 82.6 52.4 98.8 16.0 15.6 57.1 7.5 105.7 192.0 91.6 113.3 13.1 38.3 29.2 31.3 17.2 73.6 7.3 6.2 13.8 17.4 31.9 0.0 28.9 6.9 22.0 50.5 57.4 16.1 13.7 11.8 21.2 17.6 27.5 24.5 47.0 6.3 35.1 55.6 16.5 6.1 25.2 14.2 28.7 24.4 5.0 17.4 4.5 23.0 9.9 26.6 12.2 5.1 41.3 36.0 8.5 9.7 78.1 23.0 44.4 13.5 207.0 10.9 8.1 33.2 10.2 65.7 38.2 35.2 3.2 8.6 91.6 145.1 20.8 15.5 9.6 14.5 328.5 LTBP2 "C14orf141, LTBP3" ENSG00000119681 "Latent transforming growth factor beta binding protein 2" Q14767 14 74498183-74612378 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Heparin-binding" "Disease variant, Dwarfism, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 60.6;Fibroblasts: 59.5;Peritubular cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 240.8;HUVEC TERT2: 129.1;LHCN-M2: 129.4;TIME: 564.5" "Group enriched" "Detected in some" 10 "cerebellum: 5.3;olfactory bulb: 2.4" "Region enhanced" "Detected in many" "olfactory bulb: 15.4" HPA003415 Approved Approved Nucleoplasm "Secreted to extracellular matrix" NA NA 14000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA003415: AB_1079284" "unprognostic (1.24e-1)" "unprognostic (3.09e-2)" "unprognostic (5.10e-2)" "unprognostic (3.92e-3)" "unprognostic (2.08e-3)" "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (4.43e-2)" "unprognostic (1.08e-1)" "unprognostic (1.61e-1)" "unprognostic (2.80e-2)" "unprognostic (3.77e-1)" "unprognostic (1.98e-3)" "unprognostic (2.22e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.94e-4)" 34.2 4.0 1.1 15.2 2.9 0.6 24.4 4.1 5.6 66.2 9.5 6.6 3.1 22.5 23.9 10.7 11.7 33.1 45.4 1.2 1.1 4.1 2.1 64.9 8.3 2.2 1.1 39.4 8.7 9.6 7.3 28.0 1.4 15.7 2.6 2.3 26.7 19.6 13.6 12.6 6.9 16.0 2.2 3.9 8.5 5.4 1.9 3.1 53.0 21.4 6.1 14.2 21.6 1.0 2.5 4.9 1.2 0.2 36.9 67.7 0.2 47.4 16.2 9.2 5.7 0.0 17.4 0.4 13.8 240.8 4.1 4.8 0.2 17.7 3.8 0.2 0.8 0.8 2.2 2.1 8.8 0.1 0.6 70.2 7.7 50.7 29.1 68.9 129.1 0.1 0.2 0.1 129.4 1.1 0.1 0.3 0.3 0.2 4.5 0.5 1.1 0.1 11.3 6.7 1.0 3.3 33.1 0.1 1.1 3.4 1.1 0.2 564.5 3.3 54.0 17.0 18.0 0.7 0.7 0.1 13.1 0.3 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 2.9 4.1 5.6 1.2 1.1 2.2 1.1 1.4 2.2 1.9 1.0 3.8 0.0 2.2 2.3 0.1 5.6 15.1 13.0 13.1 2.1 1.9 60.6 6.4 0.0 6.1 0.0 0.0 0.5 1.2 0.1 5.9 1.4 1.2 0.5 7.9 6.5 0.0 5.7 1.1 0.4 0.3 59.5 1.5 0.9 1.3 1.9 9.3 0.4 4.2 3.3 0.7 0.0 20.3 0.3 5.8 5.8 16.4 3.7 0.0 22.5 0.1 0.4 0.0 1.0 0.3 4.4 0.0 82.4 0.3 10.7 0.0 0.0 0.3 1.0 6.6 3.2 10.8 2.8 3.8 5.2 1.0 1.2 0.9 2.2 0.1 2.1 LUZP1 LUZP ENSG00000169641 "Leucine zipper protein 1" Q86V48 1 23084023-23177808 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 349.1;Early spermatids: 291.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 127.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028506, HPA028542" Enhanced Approved "Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "HPA028506: AB_10600083, HPA028542: AB_10601986" "unprognostic (3.04e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (7.35e-3)" "unprognostic (7.20e-2)" "unprognostic (3.96e-2)" "unprognostic (8.27e-2)" "unprognostic (8.46e-3)" "unprognostic (9.77e-3)" "unprognostic (7.34e-2)" "unprognostic (2.56e-3)" "unprognostic (1.19e-1)" "unprognostic (3.50e-1)" "prognostic favorable (1.46e-7)" "unprognostic (4.49e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-1)" "unprognostic (1.33e-1)" 11.5 14.3 6.0 9.2 8.1 14.2 7.3 6.3 24.6 10.1 4.1 13.1 22.7 11.9 5.4 9.3 6.3 13.0 13.6 7.6 10.9 10.7 3.6 10.4 6.4 13.7 8.1 7.6 6.1 20.1 3.8 12.7 13.9 9.8 13.2 5.4 6.9 9.6 3.3 8.9 24.7 12.8 5.1 10.7 5.2 11.4 12.3 9.8 9.5 6.6 7.1 10.4 7.4 11.0 26.4 17.7 24.5 28.5 24.6 31.3 17.8 25.3 40.1 31.0 32.4 10.1 12.0 0.5 22.6 43.0 19.9 34.8 24.5 68.5 37.6 9.6 16.2 36.6 21.8 9.6 16.2 18.5 22.5 27.7 26.4 45.6 35.6 25.6 70.6 10.0 13.6 2.0 25.2 7.0 12.6 7.9 20.8 8.1 18.9 18.9 36.7 3.1 14.0 17.1 4.5 11.6 60.4 16.8 20.3 48.9 9.6 9.6 127.0 36.2 27.2 27.2 25.4 3.0 7.8 9.8 15.9 29.8 31.8 39.8 7.6 8.4 11.5 5.4 13.1 3.2 8.7 7.5 7.6 5.8 6.9 6.9 4.1 7.1 10.9 15.8 5.1 3.3 6.0 8.1 6.3 24.6 7.6 10.9 13.7 8.1 13.9 5.1 12.3 11.0 103.5 9.6 14.1 58.1 17.1 135.2 349.1 64.7 117.8 23.7 31.3 41.7 54.7 27.1 33.7 20.2 2.1 25.6 34.1 100.3 15.6 58.6 291.4 35.6 83.0 138.2 21.5 9.5 113.2 30.6 53.7 49.4 14.3 54.1 22.8 21.9 68.6 11.5 27.3 21.9 111.3 55.8 61.1 18.0 77.9 52.9 36.4 36.4 33.8 65.6 83.7 17.4 33.0 38.2 7.2 75.9 54.0 43.6 19.5 83.5 117.3 23.3 24.0 8.4 32.9 43.7 67.5 84.6 85.9 72.9 70.8 24.8 46.3 38.4 54.9 183.0 LYVE1 "LYVE-1, XLKD1" ENSG00000133800 "Lymphatic vessel endothelial hyaluronan receptor 1" Q9Y5Y7 11 10556966-10611689 "Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 126.4;placenta: 149.3" "Group enriched" "Detected in many" 4 "Hepatic stellate cells: 238.8;Hofbauer cells: 807.4;Kupffer cells: 338.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "HUVEC TERT2: 81.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 1.8" "CAB025860, HPA042953" Supported NA NA 3300000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB025860: , HPA042953: AB_2678238" "unprognostic (9.83e-2)" "unprognostic (1.52e-1)" "unprognostic (1.87e-1)" "unprognostic (3.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.07e-4)" "unprognostic (7.53e-2)" "unprognostic (4.09e-2)" "prognostic unfavorable (6.98e-5)" "unprognostic (1.67e-2)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.43e-3)" 126.4 68.9 2.7 19.3 3.5 0.9 37.3 2.0 5.1 17.6 8.9 19.9 13.3 8.1 5.7 26.2 23.0 20.2 13.5 2.9 2.4 8.1 44.2 23.8 8.4 3.0 2.2 11.8 4.9 2.3 2.7 149.3 3.1 4.0 20.0 0.3 5.4 11.2 5.0 7.1 17.6 67.1 2.1 61.6 10.5 4.3 3.3 1.7 13.5 27.4 3.0 35.1 6.8 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 81.6 0.0 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 3.5 2.0 5.1 2.9 2.4 3.0 2.2 3.1 2.1 3.3 3.2 5.7 0.0 2.8 8.1 2.1 3.7 0.1 0.0 0.0 0.0 0.5 0.3 4.6 8.6 0.0 0.0 0.0 5.3 0.3 0.0 0.0 0.0 1.0 0.0 0.2 102.7 0.0 5.3 0.8 0.0 5.7 3.4 0.0 0.0 1.3 0.0 238.8 4.5 807.4 0.0 0.4 0.0 0.0 338.1 10.7 2.3 3.7 86.0 7.2 12.2 0.1 0.0 0.0 0.5 0.6 0.0 0.0 0.4 2.7 0.2 0.0 0.0 1.5 0.0 13.1 3.4 6.8 0.0 0.0 1.4 3.3 11.1 1.4 0.7 0.0 0.2 MAMDC2 MGC21981 ENSG00000165072 "MAM domain containing 2" Q7Z304 9 70043848-70226972 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 74.5" "Cell type enhanced" "Detected in many" "Early spermatids: 42.5;Excitatory neurons: 37.0;Fibroblasts: 38.7;Inhibitory neurons: 42.9;Leydig cells: 96.6;Microglial cells: 45.9;Peritubular cells: 82.0;Sertoli cells: 39.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 55.7;HHSteC: 57.2;LHCN-M2: 75.0;TIME: 71.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021814, HPA022249" Uncertain Approved "Nuclear speckles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Plasma membrane" "HPA021814: AB_1853508, HPA022249: AB_2139157" "unprognostic (1.88e-1)" "unprognostic (3.16e-3)" "unprognostic (2.21e-3)" "unprognostic (2.71e-2)" "unprognostic (4.30e-2)" "unprognostic (8.49e-2)" "unprognostic (1.27e-2)" "unprognostic (8.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.92e-1)" "unprognostic (3.67e-1)" "unprognostic (3.03e-2)" "unprognostic (4.23e-3)" "unprognostic (2.35e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (2.79e-3)" 17.2 8.2 1.0 1.2 1.2 0.2 15.6 0.8 1.6 30.4 2.3 45.5 8.4 74.5 19.1 21.2 58.5 13.0 15.4 0.7 1.5 2.6 1.2 37.2 0.5 0.7 1.2 49.1 3.7 1.8 0.8 4.3 0.7 7.7 12.3 5.7 9.9 10.8 6.6 9.2 21.6 25.3 0.7 16.1 19.1 7.5 1.8 1.6 8.0 17.1 3.1 32.3 18.5 1.1 0.3 0.0 0.7 0.0 55.7 18.8 1.7 11.1 5.0 2.7 4.6 0.0 1.2 0.0 0.7 2.1 1.5 9.1 0.1 0.8 2.3 0.0 0.0 0.0 15.6 0.1 57.2 0.0 0.0 3.6 0.7 1.7 0.9 19.9 4.9 0.0 0.0 0.5 75.0 0.0 0.0 0.1 7.7 0.1 0.0 0.0 8.8 7.3 24.6 0.0 0.7 0.0 0.1 0.1 0.0 20.8 0.0 0.0 71.0 0.0 1.8 0.1 2.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.0 1.2 0.8 1.6 0.7 1.5 0.7 1.2 0.7 0.7 1.8 1.1 2.0 0.0 1.5 20.2 0.5 6.1 0.5 0.4 0.6 0.8 0.5 10.8 4.3 0.0 0.1 3.7 4.2 0.2 0.2 0.2 0.0 0.1 42.5 0.7 13.7 3.9 0.0 0.0 37.0 0.2 6.6 38.7 0.5 0.5 1.3 0.3 0.4 0.0 3.3 0.0 42.9 0.1 0.0 0.0 17.5 11.4 96.6 13.6 10.6 45.9 0.0 13.8 0.0 11.6 23.3 0.4 0.2 82.0 0.0 0.1 0.0 0.5 0.1 0.5 39.5 4.8 22.4 0.4 0.4 1.1 4.8 0.3 0.8 0.1 0.1 0.1 MAP1B "MAP5, PPP1R102" ENSG00000131711 "Microtubule associated protein 1B" P46821 5 72107234-72209565 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 431.3;retina: 154.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 717.2;Excitatory neurons: 571.8;Horizontal cells: 647.8;Rod photoreceptor cells: 562.1;Sertoli cells: 769.2;Smooth muscle cells: 461.2" "Cancer enriched" "Detected in all" 5 "glioma: 48.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 301.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009792, HPA022275" Enhanced Supported Enhanced Cytosol NA NA 180000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB009792: AB_2137420, HPA022275: AB_1853944" "unprognostic (9.96e-2)" "unprognostic (3.97e-2)" "unprognostic (1.57e-2)" "unprognostic (3.70e-1)" "unprognostic (4.67e-3)" "unprognostic (2.98e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (7.00e-2)" "unprognostic (4.78e-3)" "unprognostic (1.32e-1)" "unprognostic (1.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.90e-1)" "unprognostic (1.75e-2)" "prognostic unfavorable (8.22e-5)" 30.2 19.4 135.6 10.9 127.6 0.1 17.8 181.9 299.9 14.9 0.0 16.9 2.1 16.6 9.5 13.0 11.5 11.0 25.8 138.9 310.5 4.0 2.2 7.1 2.2 392.1 297.1 7.0 3.6 2.5 16.4 10.0 431.3 20.1 5.3 154.9 7.7 25.4 6.0 13.3 7.1 26.4 222.4 1.3 15.3 12.0 332.9 1.5 8.3 9.6 1.3 26.7 11.4 272.0 1.4 62.8 133.5 48.7 80.9 140.1 0.2 32.6 22.7 29.0 34.5 0.5 1.7 0.1 71.8 108.2 87.9 0.6 73.2 2.8 43.3 0.2 12.3 6.7 22.3 18.3 43.6 0.0 5.1 142.1 9.3 116.7 42.8 25.9 91.6 0.2 10.6 0.3 49.5 0.6 0.1 0.0 36.5 0.0 21.3 0.4 16.4 0.1 2.5 0.1 89.9 63.0 28.9 0.3 14.9 109.7 0.2 6.1 301.6 90.7 44.6 69.4 140.3 8.0 0.4 0.2 98.5 0.1 72.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 135.6 127.6 181.9 299.9 138.9 310.5 392.1 297.1 431.3 222.4 332.9 272.0 45.6 0.0 2.0 85.5 1.5 31.6 71.3 2.3 5.2 240.3 14.3 34.3 366.0 2.8 11.5 9.2 717.2 1.6 0.6 0.0 0.0 12.9 13.2 75.4 116.8 97.8 77.6 0.0 571.8 3.4 1.4 220.6 6.6 27.7 1.3 25.3 42.1 0.8 6.4 647.8 350.7 0.7 18.3 1.3 28.4 23.4 309.7 10.1 80.0 91.8 0.0 406.1 0.0 131.2 269.3 7.1 0.0 384.8 0.5 22.1 0.1 0.9 48.6 562.1 769.2 85.4 461.2 8.9 8.0 1.9 50.6 4.0 4.2 269.9 0.2 20.0 MAP3K3 "MAPKKK3, MEKK3" ENSG00000198909 "Mitogen-activated protein kinase kinase kinase 3" Q99759 17 63622415-63696305 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007764, HPA035410, HPA035411" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "CAB007764: AB_562314, HPA035410: AB_2674614, HPA035411: AB_2674615" "unprognostic (9.65e-3)" "unprognostic (1.33e-1)" "unprognostic (5.14e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (4.12e-2)" "unprognostic (1.03e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (9.37e-2)" "unprognostic (1.46e-3)" "unprognostic (5.51e-2)" "unprognostic (2.35e-1)" "unprognostic (2.79e-2)" "unprognostic (4.68e-2)" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" 30.1 12.3 11.3 23.7 12.4 31.5 23.6 13.9 12.3 21.6 13.6 28.8 8.7 23.8 6.5 17.7 24.2 21.8 40.9 10.5 12.1 22.9 13.9 28.7 22.3 14.9 12.7 24.0 12.9 15.2 13.8 22.9 13.2 22.2 8.5 6.9 15.1 18.4 23.7 19.3 18.7 22.0 13.1 34.5 18.7 17.2 12.9 15.1 18.0 30.3 14.5 23.4 19.1 13.6 22.6 16.3 20.4 20.1 37.7 30.2 9.4 22.0 24.4 27.0 21.2 7.8 4.5 24.2 15.0 43.2 18.7 8.3 13.4 15.5 16.9 21.7 29.3 19.6 22.6 11.0 19.5 15.6 20.1 22.3 10.4 33.6 17.1 16.3 65.7 17.4 12.2 31.1 21.4 15.9 27.3 15.9 12.5 4.5 16.8 14.3 53.0 15.6 9.4 10.3 10.6 25.3 14.6 17.1 17.9 24.9 17.3 14.8 60.5 67.8 17.8 37.3 26.9 30.3 33.6 8.9 14.4 12.0 18.0 15.0 11.4 15.3 2.8 11.8 3.0 2.0 3.4 2.8 4.9 2.4 3.3 3.2 25.1 1.9 12.5 1.9 2.9 3.5 11.3 12.4 13.9 12.3 10.5 12.1 14.9 12.7 13.2 13.1 12.9 13.6 31.6 19.2 14.5 23.5 11.0 7.8 5.4 3.9 5.7 15.8 9.5 8.9 10.3 12.8 5.1 16.5 14.6 3.2 25.8 3.3 9.8 4.5 8.3 10.0 12.3 33.0 4.2 2.1 39.8 8.1 3.3 13.6 3.1 9.3 3.8 7.1 48.2 10.1 16.3 18.5 34.2 3.9 2.0 47.1 13.0 6.4 14.9 35.1 23.2 54.4 42.7 8.8 24.7 31.2 36.1 5.2 1.9 13.2 8.3 8.2 3.7 2.4 5.4 14.0 19.7 21.9 12.9 23.9 17.8 6.1 11.2 1.4 15.6 6.2 4.5 3.8 MAP4 ENSG00000047849 "Microtubule associated protein 4" P27816 3 47850690-48089272 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 743.9" "Cell type enhanced" "Detected in all" "Bipolar cells: 392.2;Cardiomyocytes: 921.5;Cone photoreceptor cells: 625.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038149, HPA038150" Enhanced Approved "Plasma membrane,Microtubules,Cytosol" NA NA 880000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Microtubules, Cytosol" "Plasma membrane" "HPA038149: AB_10672471, HPA038150: AB_10672505" "unprognostic (2.51e-1)" "unprognostic (4.48e-1)" "unprognostic (2.72e-1)" "unprognostic (1.95e-2)" "unprognostic (3.36e-1)" "unprognostic (4.57e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (6.82e-2)" "unprognostic (1.46e-2)" "unprognostic (5.02e-2)" "unprognostic (2.23e-2)" "unprognostic (1.30e-2)" "unprognostic (2.25e-2)" "unprognostic (8.89e-2)" "unprognostic (6.45e-2)" "unprognostic (1.88e-1)" "unprognostic (1.21e-3)" 127.4 55.7 475.5 50.4 483.4 16.1 98.0 433.2 406.8 118.0 215.5 193.2 35.1 111.7 69.7 90.7 94.7 52.9 380.9 351.2 408.7 88.3 66.0 105.0 35.0 567.9 490.6 90.0 71.4 31.4 56.1 64.8 509.2 92.7 47.6 149.0 71.4 88.1 743.9 120.6 80.6 94.5 526.1 64.0 93.9 80.0 552.3 42.1 61.1 491.0 37.8 135.5 115.2 533.2 121.9 95.7 117.1 89.3 168.6 298.5 49.5 222.6 241.2 184.1 204.9 81.3 74.4 102.3 50.7 337.9 172.8 79.2 151.4 201.6 204.7 148.7 63.8 69.3 102.8 106.0 228.6 48.6 53.9 251.4 246.4 224.0 271.6 167.1 245.1 70.6 91.2 115.3 146.9 69.1 69.5 58.9 70.9 59.9 195.0 36.6 110.1 128.1 118.2 100.1 46.4 72.3 171.0 68.3 118.6 163.0 50.1 44.8 334.5 172.7 132.3 182.9 144.4 80.4 66.9 47.8 222.2 58.6 167.3 10.5 6.6 3.7 15.6 10.6 7.5 12.3 10.2 12.7 7.1 11.5 4.9 7.6 2.6 13.4 27.3 10.8 13.0 9.7 475.5 483.4 433.2 406.8 351.2 408.7 567.9 490.6 509.2 526.1 552.3 533.2 147.9 70.5 48.2 124.4 45.1 74.8 55.4 53.1 42.7 392.2 34.7 36.2 921.5 48.6 53.4 80.9 625.5 33.8 54.6 43.7 27.4 97.8 116.2 78.2 143.2 110.4 28.8 21.6 63.7 65.3 81.0 105.5 39.8 93.4 27.8 81.6 50.0 57.3 38.0 47.1 71.2 31.7 34.6 28.3 50.5 38.8 77.0 40.0 78.2 95.5 72.0 82.8 47.4 77.9 167.2 92.0 28.0 103.0 47.2 89.0 37.1 39.2 43.6 97.5 72.3 149.0 119.0 65.6 64.3 58.7 69.6 22.4 60.5 137.4 39.5 44.7 MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894689 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 472.1" "Cell type enhanced" "Detected in many" "Microglial cells: 337.3;Oligodendrocytes: 1134.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008476: AB_1079362" "unprognostic (6.40e-2)" "unprognostic (1.09e-2)" "unprognostic (4.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (4.29e-2)" "unprognostic (9.79e-2)" "unprognostic (2.22e-3)" "unprognostic (8.65e-2)" "prognostic unfavorable (3.62e-6)" "unprognostic (6.67e-3)" "unprognostic (8.98e-2)" "unprognostic (3.15e-1)" "unprognostic (7.14e-3)" 54.1 9.1 272.6 42.9 316.1 72.5 32.2 208.8 252.5 23.9 95.0 21.1 10.6 27.4 12.1 35.2 19.7 34.5 44.8 219.4 256.3 15.0 32.8 29.2 54.1 317.5 286.1 23.1 16.1 15.0 10.0 49.4 273.1 13.9 17.8 22.7 19.3 10.2 37.4 21.1 17.7 28.7 246.7 24.2 22.0 40.1 348.5 44.3 15.8 30.6 60.1 33.1 25.6 472.1 112.7 83.8 175.2 84.3 162.4 288.6 219.5 139.8 114.3 122.2 100.1 139.5 145.6 163.1 118.3 210.3 36.0 45.5 56.0 123.2 121.1 219.8 38.0 122.4 62.5 367.7 136.7 59.1 5.5 261.3 55.3 301.9 133.5 122.1 322.5 90.3 80.9 0.4 325.4 61.3 137.8 36.5 89.2 42.5 131.5 164.1 120.0 0.6 81.2 38.8 68.5 113.6 96.5 0.4 104.0 160.8 22.4 105.1 409.1 240.5 102.9 70.6 168.6 0.3 0.4 96.7 155.2 73.2 180.1 8.8 3.2 0.0 2.3 3.2 1.6 3.4 2.9 1.5 1.1 5.0 2.2 2.5 13.5 1.1 3.1 6.0 3.7 1.5 272.6 316.1 208.8 252.5 219.4 256.3 317.5 286.1 273.1 246.7 348.5 472.1 104.3 19.2 23.9 283.0 64.5 30.0 41.9 17.4 12.5 109.1 14.3 17.4 71.0 28.6 29.6 18.4 50.1 13.1 38.4 12.0 0.0 57.4 31.5 67.2 77.1 84.2 17.4 48.0 197.5 53.2 23.4 49.7 26.5 101.0 24.0 151.8 67.1 39.2 38.8 35.3 122.4 13.6 14.2 26.9 245.9 46.0 55.0 54.7 19.6 337.3 88.0 49.2 10.3 228.7 1134.5 128.1 12.0 17.3 18.0 72.1 5.3 6.3 22.9 10.4 52.6 65.2 73.3 29.0 82.1 24.3 24.6 7.8 38.4 17.2 14.4 40.4 MAPK3 "ERK1, p44erk1, p44mapk, PRKM3" ENSG00000102882 "Mitogen-activated protein kinase 3" P27361 16 30114105-30123506 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 336.9;Early spermatids: 267.2;Proximal enterocytes: 235.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 49.1;neutrophil: 21.5" "Lineage enriched" "Detected in all" 7 "granulocytes: 49.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002683, HPA003995, HPA005700, HPA030069" Approved Supported Nucleoplasm NA NA 46000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB002683: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (5.03e-2)" "unprognostic (4.62e-2)" "unprognostic (3.46e-2)" "unprognostic (1.60e-1)" "unprognostic (4.70e-3)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (2.09e-2)" "unprognostic (3.59e-2)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (3.51e-2)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-2)" 99.5 64.3 178.7 42.4 162.3 45.2 86.3 113.0 200.9 93.3 86.0 117.2 103.1 74.9 27.4 129.6 71.6 65.3 65.4 168.6 132.7 49.4 21.2 71.3 37.8 135.6 148.7 78.7 33.7 61.2 55.8 70.2 142.3 49.2 91.9 71.5 61.0 43.3 51.7 77.6 113.2 58.7 127.4 57.4 86.4 31.6 129.5 31.4 58.0 57.0 49.3 64.8 89.0 130.9 56.3 30.0 62.2 35.7 153.7 202.4 35.1 40.7 101.1 63.4 75.3 36.4 110.0 56.3 39.7 115.5 73.2 20.6 53.3 47.8 61.0 106.9 61.8 17.3 31.6 61.8 154.2 13.0 46.2 125.8 27.3 72.5 32.2 96.1 163.7 60.3 24.3 70.0 85.2 147.1 59.2 21.5 16.9 113.6 26.1 68.9 37.3 127.4 58.0 35.0 55.2 39.3 23.2 81.8 24.1 50.5 53.5 30.7 117.2 41.7 35.4 48.4 14.5 79.1 39.3 29.6 83.3 27.1 30.0 6.2 5.1 49.1 1.6 3.7 2.6 2.3 3.7 3.0 2.8 2.5 2.6 2.9 21.5 2.2 2.0 2.8 6.6 2.8 178.7 162.3 113.0 200.9 168.6 132.7 135.6 148.7 142.3 127.4 129.5 130.9 95.5 22.4 17.5 7.5 10.7 9.8 22.2 11.4 5.7 30.4 23.3 19.9 15.4 20.0 13.0 9.2 22.9 77.6 15.2 336.9 23.5 39.8 267.2 24.8 25.1 68.1 54.7 6.1 7.7 61.2 134.2 34.7 79.0 15.7 2.5 19.1 71.7 7.0 45.2 8.4 10.3 159.3 22.4 26.4 12.3 176.0 32.3 20.6 23.2 7.5 24.5 67.0 13.4 7.1 9.8 118.8 167.2 27.4 6.2 13.5 235.6 23.9 24.7 41.5 19.7 18.8 29.3 10.9 19.8 15.8 13.2 33.8 14.5 40.0 94.9 22.4 MARCHF3 "MARCH-III, MARCH3, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 43.8;Syncytiotrophoblasts: 98.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.5;naive B-cell: 12.1" "Lineage enriched" "Detected in many" 4 "B-cells: 12.1" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 40.4;HUVEC TERT2: 27.4;TIME: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" 5.6 2.8 6.1 2.9 5.6 3.7 2.6 5.3 4.1 0.9 1.9 5.3 0.9 1.4 0.0 1.4 1.5 5.2 7.8 3.9 5.7 0.8 0.7 2.4 2.5 11.5 7.1 1.1 2.4 0.3 2.4 1.7 7.9 0.6 5.6 7.4 4.6 0.2 6.5 5.8 2.4 2.9 8.3 1.6 2.4 5.6 7.8 1.3 1.4 3.3 2.1 7.6 0.7 8.5 0.4 1.8 3.9 2.1 3.4 3.2 1.2 14.2 5.9 11.1 16.3 1.9 0.8 3.8 1.3 1.9 2.4 1.1 4.9 2.5 15.3 0.8 4.7 12.2 3.2 1.9 5.6 5.0 3.0 2.4 0.7 40.4 4.8 2.6 27.4 0.6 5.1 0.7 9.3 1.3 0.5 2.3 3.3 3.0 4.6 1.5 15.5 1.2 0.9 2.0 1.3 0.9 3.3 0.5 1.6 1.9 2.9 5.0 33.5 2.2 1.8 12.6 1.6 1.9 2.3 2.3 8.3 3.8 2.0 0.0 0.2 2.8 0.5 0.4 0.1 10.5 0.6 0.3 0.1 12.1 2.3 0.5 0.8 2.3 0.3 0.7 2.9 0.8 6.1 5.6 5.3 4.1 3.9 5.7 11.5 7.1 7.9 8.3 7.8 8.5 3.8 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 43.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 98.6 0.6 0.0 0.0 0.0 MARCHF7 "AXOT, MARCH-VII, MARCH7, RNF177" ENSG00000136536 "Membrane associated ring-CH-type finger 7" Q9H992 2 159712457-159771027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 33.3;Cardiomyocytes: 88.4;Cytotrophoblasts: 36.2;dendritic cells: 28.2;Extravillous trophoblasts: 38.8;Hofbauer cells: 34.0;Syncytiotrophoblasts: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014275, HPA022152" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA014275: AB_10599820, HPA022152: AB_10601107" "unprognostic (2.42e-1)" "unprognostic (2.24e-1)" "unprognostic (1.02e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (2.46e-2)" "unprognostic (6.42e-2)" "unprognostic (3.44e-1)" "unprognostic (3.17e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.84e-4)" "unprognostic (1.41e-3)" "unprognostic (1.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.61e-1)" 38.3 30.0 16.4 37.9 21.7 43.2 48.2 32.3 21.5 38.6 25.1 33.2 30.0 45.0 34.2 67.3 37.5 38.1 48.9 15.8 16.1 32.8 40.1 38.2 47.9 17.4 17.1 47.5 22.3 36.6 22.7 46.9 17.7 38.1 36.9 37.9 26.9 36.3 55.2 38.6 30.0 50.6 14.9 45.1 33.5 62.0 17.1 60.8 47.5 44.1 52.2 39.0 37.5 21.8 50.3 35.3 88.7 40.7 61.9 81.9 89.1 83.9 81.1 82.5 73.9 70.9 57.5 71.0 36.8 84.2 46.8 61.3 55.4 74.5 102.9 75.9 43.2 96.0 53.8 53.3 60.7 79.9 72.6 72.7 83.0 99.5 86.5 92.5 99.3 50.7 75.6 65.6 82.9 44.2 52.4 73.8 84.6 54.6 47.3 75.0 64.5 59.3 74.6 112.1 51.9 48.6 65.6 48.2 67.0 94.3 56.9 94.4 93.5 86.9 51.9 53.9 47.2 51.5 61.0 96.8 54.1 46.8 84.0 83.5 28.8 59.6 28.6 29.5 33.3 27.6 30.4 32.4 27.6 26.4 36.3 35.9 127.5 39.4 43.4 22.3 34.3 30.9 16.4 21.7 32.3 21.5 15.8 16.1 17.4 17.1 17.7 14.9 17.1 21.8 33.3 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.4 0.0 0.0 0.0 0.0 36.2 28.2 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 38.8 13.5 0.0 0.0 0.0 0.0 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 44.2 5.8 0.0 0.0 0.0 MARF1 "KIAA0430, LKAP, LMKB, PPP1R34" ENSG00000166783 "Meiosis regulator and mRNA stability factor 1" Q9Y4F3 16 15594387-15643154 "Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 28.7;Breast glandular cells: 26.3;Endometrial stromal cells: 27.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017992 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus, Vesicles" "HPA017992: AB_1852921" "unprognostic (2.33e-1)" "unprognostic (6.44e-3)" "unprognostic (8.84e-2)" "unprognostic (3.78e-2)" "unprognostic (1.28e-1)" "unprognostic (6.13e-3)" "unprognostic (2.35e-1)" "unprognostic (2.10e-2)" "unprognostic (2.47e-2)" "unprognostic (6.93e-2)" "unprognostic (8.44e-3)" "unprognostic (1.35e-1)" "unprognostic (6.94e-3)" "unprognostic (3.08e-2)" "unprognostic (1.24e-1)" "unprognostic (8.74e-2)" "unprognostic (7.94e-2)" 10.5 7.1 2.1 10.8 5.2 9.7 9.4 1.5 6.6 10.0 3.7 16.0 10.4 12.8 1.0 12.3 13.7 12.5 9.2 4.5 3.4 13.5 8.3 9.3 14.6 3.6 4.5 18.2 12.9 12.3 5.9 9.4 2.6 10.4 12.1 8.4 14.4 13.7 18.3 10.5 11.2 12.0 0.0 12.1 10.1 4.9 4.4 12.7 14.8 15.2 22.0 12.1 8.8 4.5 8.3 9.4 15.0 8.2 12.1 22.4 7.2 9.6 12.4 8.2 13.5 2.7 6.2 29.8 17.0 12.3 6.7 5.6 7.7 12.4 13.6 11.6 5.0 13.1 12.3 10.4 13.4 15.7 10.5 13.4 13.4 15.3 15.5 16.9 19.5 12.8 12.6 13.3 15.6 7.7 13.9 2.6 5.6 7.1 7.2 19.5 22.0 5.9 7.1 6.4 9.1 10.8 7.7 8.9 14.3 6.7 9.2 13.2 19.7 11.2 5.5 11.6 6.3 12.3 12.9 15.9 12.4 9.6 16.4 2.5 0.7 4.6 1.1 1.2 0.7 4.1 1.7 1.3 0.8 5.2 1.9 1.4 7.1 0.9 1.8 0.3 1.7 0.9 2.1 5.2 1.5 6.6 4.5 3.4 3.6 4.5 2.6 0.0 4.4 4.5 21.4 22.4 28.7 0.0 10.7 0.0 0.0 0.0 0.0 0.0 26.3 19.8 0.0 0.0 18.6 23.9 0.0 5.7 14.7 0.0 15.6 10.4 0.0 17.8 27.5 8.4 0.0 0.0 0.0 14.2 5.9 7.7 0.0 20.0 11.4 23.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 7.2 0.0 0.0 0.0 0.0 13.7 0.0 0.0 6.8 0.0 0.0 19.0 17.5 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 7.7 7.8 17.9 0.0 0.0 ME3 ENSG00000151376 "Malic enzyme 3" Q16798 11 86441108-86672636 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 54.2;Excitatory neurons: 103.7;Inhibitory neurons: 147.8;Oligodendrocyte precursor cells: 75.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 54.4;hTERT-RPE1: 64.1;HUVEC TERT2: 36.3;TIME: 40.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA038473 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA038473: AB_10672747" "unprognostic (1.83e-3)" "unprognostic (8.00e-2)" "unprognostic (1.99e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-1)" "unprognostic (2.91e-1)" "unprognostic (5.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-1)" "unprognostic (1.20e-1)" "unprognostic (5.74e-2)" "unprognostic (2.97e-1)" "unprognostic (1.65e-1)" "unprognostic (2.73e-1)" "unprognostic (2.96e-2)" "prognostic favorable (3.86e-4)" 17.4 24.4 25.5 5.0 27.2 6.2 19.5 12.2 31.5 24.5 14.4 16.4 7.1 16.7 5.6 4.2 13.6 11.5 26.2 27.0 15.7 25.1 6.2 11.3 4.2 24.8 25.9 27.9 15.9 16.2 22.4 4.7 22.9 19.9 13.7 10.8 12.6 9.0 21.9 4.5 8.9 14.1 5.3 10.9 21.0 13.0 20.4 3.5 12.5 19.5 2.4 17.1 14.2 16.5 0.0 18.1 5.2 0.0 7.9 16.6 0.1 5.9 9.6 12.9 16.0 14.0 54.4 0.0 5.3 5.7 31.5 0.2 0.0 0.1 5.6 9.2 0.0 9.6 16.8 0.0 11.9 1.2 0.0 11.8 2.8 10.2 0.1 64.1 36.3 0.0 0.2 0.0 9.1 1.8 2.7 0.1 1.2 1.7 7.7 8.3 0.0 0.6 11.4 21.4 6.2 0.1 3.8 0.1 0.0 2.1 0.9 1.5 40.0 1.5 1.2 26.3 0.9 0.1 3.3 0.0 1.4 17.1 1.6 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.7 1.2 2.3 0.0 0.9 1.1 0.0 1.0 0.1 0.3 0.0 0.5 25.5 27.2 12.2 31.5 27.0 15.7 24.8 25.9 22.9 5.3 20.4 16.5 13.6 3.2 3.3 30.3 1.1 2.3 4.6 5.4 5.7 16.5 7.5 9.1 54.2 2.8 8.1 3.7 0.0 0.3 1.9 19.2 43.0 9.1 0.7 3.2 6.1 11.5 9.0 4.2 103.7 7.9 0.4 8.4 19.9 1.6 0.0 33.4 14.6 1.6 6.8 20.2 147.8 14.8 4.1 1.6 3.5 2.5 6.2 1.8 1.8 14.0 1.1 2.0 1.0 75.4 4.8 11.5 21.1 6.4 0.5 6.4 3.5 6.5 14.9 2.5 13.1 7.0 8.2 0.4 0.2 2.6 1.6 0.0 1.6 38.8 11.0 6.6 MGARP "C4orf49, CESP-1, HUMMR, OSAP" ENSG00000137463 "Mitochondria localized glutamic acid rich protein" Q8TDB4 4 139266165-139280225 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 228.0;retina: 116.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 151.3;Granulosa cells: 93.5;Horizontal cells: 208.6;Muller glia cells: 508.9;Theca cells: 474.8" "Cancer enhanced" "Detected in some" "renal cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 20.4;fHDF/TERT166: 30.7;HHSteC: 23.6;HUVEC TERT2: 61.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015994, HPA070835" Enhanced Supported Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA015994: AB_2630370, HPA070835: " "unprognostic (2.68e-1)" "unprognostic (1.73e-1)" "unprognostic (8.18e-2)" "unprognostic (4.25e-2)" "unprognostic (3.54e-2)" "unprognostic (3.11e-2)" "unprognostic (3.42e-2)" "unprognostic (1.02e-3)" "unprognostic (2.90e-2)" "unprognostic (4.96e-2)" "unprognostic (1.50e-2)" "unprognostic (1.31e-1)" "unprognostic (4.08e-2)" "unprognostic (1.47e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-2)" "unprognostic (2.36e-1)" 9.4 228.0 3.2 0.3 3.2 0.1 1.8 7.8 4.6 2.0 3.1 1.0 0.2 5.0 1.8 0.4 2.2 0.9 3.0 3.1 4.0 1.8 0.2 0.7 0.9 3.7 4.0 23.9 0.3 0.2 11.8 0.3 3.7 2.6 0.3 116.9 0.4 4.0 0.8 0.4 0.3 3.8 3.2 0.8 0.4 8.6 3.6 0.3 0.8 0.3 0.6 1.1 2.5 3.6 0.0 1.1 0.6 0.5 1.5 0.7 0.1 20.4 0.1 3.0 0.1 0.1 0.2 0.1 0.2 30.7 8.7 0.5 4.4 0.1 1.7 0.0 2.0 0.0 0.1 0.2 23.6 0.2 0.2 7.2 0.7 3.3 0.2 7.1 61.7 0.2 0.4 0.4 5.1 0.1 0.8 0.5 1.1 0.4 0.1 0.1 0.0 0.0 0.7 0.3 0.6 1.2 0.0 0.0 0.2 0.3 0.0 0.4 0.5 0.1 0.1 0.0 0.0 0.8 0.7 0.5 8.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.2 3.2 7.8 4.6 3.1 4.0 3.7 4.0 3.7 3.2 3.6 3.6 0.6 0.0 0.0 0.0 0.2 1.7 0.7 0.4 1.2 151.3 0.7 10.8 3.5 0.0 0.1 0.0 8.4 0.2 0.3 0.1 1.9 0.0 0.3 0.8 1.2 1.1 0.0 0.0 1.3 0.0 0.2 10.7 0.0 0.3 0.0 93.5 0.4 0.4 0.5 208.6 2.5 0.0 0.0 0.0 0.3 0.6 17.1 0.6 0.0 0.0 0.0 508.9 2.1 5.0 0.7 0.1 0.0 24.8 0.3 0.3 0.1 9.2 0.0 32.6 0.0 1.9 3.4 0.8 0.4 0.7 0.9 0.3 0.6 474.8 0.1 0.3 MGAT5 "GNT-V, MGAT5A" ENSG00000152127 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase" Q09328 2 134119983-134454621 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 109.5;Inhibitory neurons: 134.5;Microglial cells: 141.5;Oligodendrocyte precursor cells: 124.7;Oligodendrocytes: 495.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010919 Approved "Intracellular and membrane" NA NA 440000 "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA010919: AB_10601864" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.21e-2)" "unprognostic (3.65e-1)" "unprognostic (3.76e-1)" "unprognostic (4.45e-3)" "unprognostic (3.41e-3)" "unprognostic (5.68e-2)" "unprognostic (8.63e-3)" "unprognostic (1.59e-1)" "unprognostic (2.64e-1)" "unprognostic (5.97e-2)" "unprognostic (1.81e-2)" "unprognostic (9.27e-2)" "unprognostic (2.17e-2)" "unprognostic (1.91e-1)" 9.4 10.4 15.4 15.0 25.2 15.5 7.9 29.6 17.9 9.1 8.5 12.6 16.1 8.8 6.6 9.0 19.0 11.1 39.0 13.3 32.1 15.3 3.7 10.4 24.6 30.5 32.9 12.0 10.9 16.3 6.2 15.1 32.1 8.4 15.0 11.6 14.6 9.4 2.2 6.8 18.1 11.2 18.4 16.2 16.9 7.2 24.2 19.1 11.3 4.6 25.4 13.2 5.0 26.4 27.9 11.0 27.3 19.7 23.8 45.3 19.1 36.4 55.0 14.4 12.0 4.7 13.4 44.3 27.1 29.2 16.4 9.7 21.6 17.0 27.3 43.9 12.7 25.0 13.7 58.0 15.5 24.5 85.1 12.5 17.4 30.3 18.6 19.6 108.7 22.1 13.0 29.6 26.3 17.9 13.3 11.6 12.5 28.9 27.0 16.2 32.3 28.6 11.1 33.7 45.1 55.4 11.7 9.9 69.3 18.3 7.7 16.8 49.5 45.1 24.0 33.1 19.3 8.3 4.1 16.5 37.8 34.4 73.1 0.6 0.4 1.0 0.8 0.3 1.3 3.0 1.5 1.0 0.3 3.7 0.6 0.8 1.1 1.3 0.4 0.9 1.0 0.6 15.4 25.2 29.6 17.9 13.3 32.1 30.5 32.9 32.1 18.4 24.2 26.4 13.2 3.2 2.4 66.6 63.2 8.0 5.7 10.3 8.0 43.6 11.6 9.9 67.3 8.6 8.5 1.8 2.1 3.2 14.9 36.9 0.0 9.0 15.6 22.6 7.6 12.5 7.2 4.4 109.5 9.0 26.3 9.0 37.2 21.0 0.0 23.1 11.7 3.0 15.5 16.8 134.5 20.3 30.5 13.5 9.9 15.1 4.4 12.9 14.2 141.5 5.3 11.4 9.2 124.7 495.5 13.0 13.2 9.4 9.0 9.7 17.6 2.4 22.6 5.2 0.0 8.8 14.3 0.6 6.1 7.3 7.2 5.3 22.4 16.6 9.9 14.5 MIPOL1 CCDC193 ENSG00000151338 "Mirror-image polydactyly 1" Q8TD10 14 37197913-37552361 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 138.2;Excitatory neurons: 159.4;Inhibitory neurons: 141.1;Late spermatids: 129.2;Oligodendrocyte precursor cells: 91.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 25.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002893, HPA050179" Enhanced Approved Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA002893: AB_1079386, HPA050179: AB_2681043" "unprognostic (3.24e-1)" "unprognostic (1.33e-1)" "unprognostic (2.26e-1)" "unprognostic (4.30e-2)" "unprognostic (1.08e-1)" "unprognostic (6.29e-2)" "unprognostic (4.61e-4)" "unprognostic (2.37e-2)" "unprognostic (2.84e-2)" "unprognostic (2.39e-2)" "unprognostic (3.54e-2)" "unprognostic (8.73e-2)" "unprognostic (1.58e-1)" "unprognostic (3.17e-1)" "unprognostic (9.78e-3)" "unprognostic (3.41e-3)" "unprognostic (1.85e-2)" 2.5 2.7 1.8 1.2 1.6 0.4 4.0 1.0 1.6 4.7 1.8 2.7 1.3 4.4 2.2 3.4 3.4 3.3 2.8 1.4 1.7 4.0 1.9 2.4 0.3 1.9 1.7 6.2 4.5 6.5 2.8 1.4 1.8 5.5 2.1 2.9 3.4 3.3 2.0 1.8 1.2 3.5 1.8 1.2 3.5 7.9 1.8 0.9 5.3 2.8 0.6 3.4 3.5 1.9 5.3 2.2 0.8 7.4 5.3 8.7 0.0 4.8 3.2 4.0 5.9 2.9 3.2 0.0 4.6 4.0 1.6 6.1 0.0 6.6 5.4 0.0 7.8 0.0 3.6 12.8 3.4 0.0 0.1 5.5 6.6 1.1 12.8 4.9 25.2 0.0 10.5 0.1 6.0 5.3 0.0 0.0 3.1 3.5 16.3 0.0 0.7 0.0 5.8 5.9 6.2 0.0 6.2 5.3 5.5 5.4 6.6 0.0 13.4 0.0 3.9 0.0 5.5 0.0 0.0 0.0 0.0 0.0 9.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 1.8 1.6 1.0 1.6 1.4 1.7 1.9 1.7 1.8 1.8 1.8 1.9 7.9 76.9 59.2 41.4 1.2 4.2 15.7 5.8 18.2 13.8 8.0 6.6 14.3 11.5 55.8 9.2 52.1 0.1 0.7 1.6 9.8 4.9 138.2 5.6 13.8 10.4 9.1 1.3 159.4 7.4 0.1 16.2 14.3 6.0 46.7 10.8 3.9 3.0 0.1 11.8 141.1 1.9 6.1 1.6 5.7 129.2 8.4 5.2 7.2 45.0 0.2 6.0 1.0 91.0 24.9 11.3 0.8 9.1 0.1 16.2 0.9 4.0 70.0 23.0 0.0 19.9 16.7 36.2 15.1 6.3 6.3 0.0 4.7 16.2 3.5 8.6 MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Endothelial cells: 25.9;granulocytes: 29.1;Macrophages: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078638 Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA078638: " "unprognostic (7.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.57e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-2)" "unprognostic (3.67e-3)" "unprognostic (1.90e-1)" "unprognostic (6.64e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.60e-3)" "unprognostic (5.30e-2)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.53e-3)" 20.0 7.1 8.4 20.3 8.7 30.7 12.1 8.6 12.7 9.0 9.6 11.0 11.0 6.0 2.0 15.6 8.0 11.5 10.6 7.8 8.2 15.4 9.3 25.6 15.4 10.1 9.8 3.0 9.9 1.6 3.7 9.2 9.3 8.4 11.4 0.3 13.3 4.3 3.1 4.9 14.4 7.6 9.1 36.1 10.8 1.2 10.3 6.7 8.7 3.1 13.8 12.3 11.5 9.6 13.5 24.4 0.1 0.1 6.0 12.4 0.2 17.0 14.8 15.4 22.4 13.9 26.6 0.3 19.1 14.2 13.7 21.7 4.3 24.9 5.8 8.3 0.6 18.8 17.6 16.2 4.2 12.3 18.6 8.5 2.4 16.8 5.7 9.0 37.3 21.3 2.7 2.5 11.9 22.0 7.0 24.3 2.2 29.3 30.0 13.5 1.8 23.8 22.0 10.2 1.0 0.8 13.4 8.7 7.2 0.1 6.2 12.5 41.4 7.8 4.8 7.0 11.7 11.2 40.2 3.2 13.7 42.3 3.9 21.9 36.2 45.8 11.2 22.2 15.4 8.1 12.6 12.0 18.9 6.7 6.8 10.4 48.6 3.6 23.3 1.2 17.4 16.0 8.4 8.7 8.6 12.7 7.8 8.2 10.1 9.8 9.3 9.1 10.3 9.6 32.1 3.2 10.7 1.0 9.8 3.4 6.8 3.1 7.4 0.2 3.3 3.4 3.1 2.8 5.5 1.8 0.0 0.2 9.6 8.9 1.9 4.6 3.5 1.2 1.9 25.9 1.2 3.4 0.5 5.2 0.8 7.1 15.3 1.6 29.1 0.3 16.8 1.3 16.6 1.7 0.5 10.9 0.0 18.2 7.8 5.2 0.9 28.9 7.2 11.2 16.7 0.1 11.3 1.5 5.2 4.9 9.4 0.4 18.5 2.8 5.5 0.6 2.0 0.6 0.0 3.0 3.1 0.1 0.2 13.4 2.8 0.3 16.5 0.2 9.5 7.5 MMRN1 "ECM, EMILIN4, GPIa*, MMRN" ENSG00000138722 "Multimerin 1" Q13201 4 89879532-89954629 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Endothelial cells: 158.0;Hepatic stellate cells: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "NK-cell: 6.3;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 9 "dendritic cells: 2.2;NK-cells: 6.3" "Cell line enriched" "Detected in some" 13 "HUVEC TERT2: 1242.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA035769 Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA035769: AB_10696511" "unprognostic (1.15e-1)" "unprognostic (1.81e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (7.05e-3)" "unprognostic (1.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.88e-1)" "unprognostic (2.12e-1)" "unprognostic (9.71e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.77e-4)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (2.23e-2)" 22.6 3.8 0.8 10.9 0.8 1.8 27.3 0.8 1.1 28.5 1.4 9.9 5.4 15.0 2.8 14.5 23.1 21.1 3.6 0.6 0.9 1.1 8.7 16.1 14.0 1.4 1.4 4.9 3.4 0.5 0.7 40.1 1.2 3.8 14.9 0.5 2.7 4.6 1.1 8.2 13.5 16.8 1.1 0.6 5.2 12.7 1.5 3.7 23.1 6.6 7.6 19.6 9.8 1.1 0.0 0.0 94.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1242.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 6.3 0.0 2.2 0.2 1.2 0.8 0.8 0.8 1.1 0.6 0.9 1.4 1.4 1.2 1.1 1.5 1.1 15.4 0.0 12.0 0.3 2.3 4.2 0.1 0.0 0.0 0.0 0.7 0.1 2.2 0.0 0.6 0.0 0.0 0.0 3.9 0.0 1.9 0.0 17.7 0.3 0.7 158.0 0.0 25.9 0.2 0.0 0.0 1.9 0.0 0.4 2.5 0.1 146.3 2.4 0.6 0.0 0.1 0.0 0.0 5.7 5.9 7.7 0.3 9.1 1.8 21.5 0.7 0.8 2.1 0.0 0.4 0.0 0.0 0.0 5.0 0.4 0.0 0.0 1.5 0.4 0.0 0.3 0.9 15.4 0.0 0.8 4.5 0.0 1.6 0.0 0.0 0.1 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MOV10L1 "CHAMP, DJ402G11.8, DKFZp434B0717" ENSG00000073146 "Mov10 like RISC complex RNA helicase 1" Q9BXT6 22 50089879-50161690 "Enzymes, Predicted intracellular proteins" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 42.6" "Cell type enhanced" "Detected in some" "Early spermatids: 118.9;Late spermatids: 310.8;Spermatocytes: 80.3;Spermatogonia: 46.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 2.5;HUVEC TERT2: 12.5;TIME: 5.8" "Not detected" "Not detected" HPA019034 Approved NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "HPA019034: AB_1854070" "unprognostic (1.39e-1)" "unprognostic (2.30e-2)" "unprognostic (1.88e-2)" "unprognostic (7.91e-2)" "unprognostic (4.29e-2)" "unprognostic (4.05e-2)" "unprognostic (1.21e-1)" "unprognostic (2.69e-1)" "unprognostic (9.43e-2)" "unprognostic (7.51e-2)" "unprognostic (6.26e-2)" "unprognostic (2.03e-1)" "unprognostic (8.02e-3)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" 0.6 0.1 1.2 0.2 1.1 0.2 0.4 4.0 1.5 3.3 0.0 2.0 0.1 4.4 1.6 0.6 2.1 1.0 0.8 1.1 0.5 0.5 0.8 0.6 0.2 1.2 0.6 3.0 0.2 0.0 1.0 0.6 1.4 2.1 0.2 1.3 0.5 0.1 0.0 0.3 1.1 1.6 0.2 0.0 0.2 42.6 0.7 0.0 0.5 0.0 0.2 0.5 3.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.4 0.7 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 2.5 0.0 1.1 0.1 0.0 0.0 0.0 0.1 12.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 5.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.1 4.0 1.5 1.1 0.5 1.2 0.6 1.4 0.2 0.7 0.6 0.3 0.0 0.0 1.3 0.0 0.3 0.1 0.1 0.0 3.1 0.1 0.3 1.6 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 118.9 0.3 5.2 0.8 0.0 0.0 5.5 0.4 0.1 0.6 0.0 0.5 0.0 0.7 0.4 0.1 1.7 5.0 3.2 0.0 0.0 0.0 0.0 310.8 1.5 0.2 0.0 8.4 0.0 2.3 0.0 1.5 1.1 0.0 0.0 3.0 0.0 0.1 0.0 1.7 0.0 3.7 13.1 0.2 0.3 80.3 46.7 0.1 0.0 0.1 0.1 0.3 0.0 0.1 MROH8 "C20orf131, C20orf132, dJ621N11.3, dJ621N11.4" ENSG00000101353 "Maestro heat like repeat family member 8" 20 37101226-37179588 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 9.8" "Cell type enhanced" "Detected in many" "Adipocytes: 25.4;Breast myoepithelial cells: 33.9;Early spermatids: 33.9;Late spermatids: 31.4;Spermatocytes: 23.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.5" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.16e-2)" "unprognostic (6.65e-3)" "unprognostic (5.88e-3)" "unprognostic (1.04e-2)" "unprognostic (2.17e-2)" "unprognostic (6.92e-2)" "unprognostic (3.31e-3)" "unprognostic (2.50e-4)" "unprognostic (1.98e-1)" "unprognostic (3.00e-2)" "unprognostic (1.11e-3)" "unprognostic (9.70e-3)" "unprognostic (5.00e-9)" "unprognostic (1.39e-1)" "unprognostic (1.01e-1)" "unprognostic (3.10e-2)" "unprognostic (1.62e-1)" 0.8 0.6 2.0 0.3 2.3 1.4 0.8 3.1 3.1 0.7 2.8 1.0 0.2 1.0 4.0 0.5 1.0 0.6 1.3 2.2 2.3 0.8 1.4 0.4 0.5 1.9 2.0 0.9 0.8 0.4 2.6 0.4 2.1 1.0 0.5 3.9 1.1 0.9 2.5 1.8 0.6 0.9 1.7 0.8 0.5 9.8 2.3 0.7 0.7 2.5 0.9 0.6 0.5 2.4 0.6 0.0 0.9 0.3 1.3 0.6 0.6 0.3 0.2 0.3 0.3 1.3 0.7 1.0 0.2 0.0 0.7 0.6 0.5 0.0 0.5 0.0 0.0 0.7 1.3 0.3 0.4 0.2 0.6 0.3 0.1 0.3 0.0 0.8 0.9 0.7 0.6 0.6 0.0 0.0 0.5 1.6 0.3 0.0 0.3 0.7 0.0 0.2 0.5 0.7 0.5 0.5 0.5 0.0 0.4 0.7 0.0 0.1 1.7 1.0 0.3 0.2 0.1 0.9 0.2 1.0 0.9 0.1 0.9 1.3 0.9 0.5 0.3 0.7 0.2 0.7 0.3 0.4 0.3 0.6 0.2 0.2 4.5 0.1 0.6 1.1 0.2 0.3 2.0 2.3 3.1 3.1 2.2 2.3 1.9 2.0 2.1 1.7 2.3 2.4 25.4 3.2 0.6 17.3 2.0 0.6 1.1 0.5 1.8 6.2 6.6 33.9 3.0 7.2 0.2 0.0 8.4 3.7 0.7 1.6 0.0 0.3 33.9 2.2 6.5 4.0 1.2 3.2 15.0 0.2 1.1 5.3 6.1 2.6 0.0 11.9 1.8 3.9 2.7 0.0 17.5 1.2 0.0 1.6 1.1 31.4 1.5 3.2 1.8 3.7 1.0 5.8 1.0 7.1 8.5 0.1 1.4 3.0 3.5 0.6 4.0 2.6 1.5 4.9 0.0 1.1 11.7 23.6 5.9 1.5 0.4 1.4 1.5 3.4 1.3 0.4 MSL3 MSL3L1 ENSG00000005302 "MSL complex subunit 3" Q8N5Y2 X 11758159-11775772 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034535, HPA034536" Uncertain Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA034535: AB_10603878, HPA034536: AB_10670973" "unprognostic (2.58e-1)" "unprognostic (1.76e-3)" "unprognostic (1.04e-1)" "unprognostic (9.56e-2)" "unprognostic (5.36e-2)" "prognostic favorable (3.28e-4)" "prognostic unfavorable (4.93e-4)" "unprognostic (8.36e-2)" "unprognostic (2.48e-2)" "unprognostic (4.88e-3)" "unprognostic (2.13e-1)" "unprognostic (5.04e-2)" "prognostic unfavorable (3.14e-9)" "unprognostic (1.20e-1)" "unprognostic (2.06e-1)" "unprognostic (4.35e-1)" "prognostic favorable (2.17e-4)" 17.6 11.8 13.4 23.1 14.3 17.0 15.9 12.7 15.4 12.9 13.1 15.4 8.6 13.4 5.4 17.8 14.0 10.0 12.9 14.5 15.0 12.5 13.9 21.9 31.3 13.3 14.1 12.1 11.0 6.8 11.1 10.4 13.4 14.5 8.5 5.7 14.4 8.5 35.8 16.0 25.4 9.9 13.8 49.3 13.6 15.7 16.2 38.8 14.5 22.6 27.0 14.8 14.5 13.2 18.6 20.3 28.0 15.0 21.6 30.1 10.2 24.0 21.9 25.2 30.9 13.7 16.8 22.5 25.2 21.6 16.2 14.0 29.7 17.0 34.1 12.6 20.2 14.0 23.0 7.0 18.5 19.6 20.8 18.7 21.6 29.1 10.9 20.6 38.4 26.6 22.2 14.2 24.5 18.3 19.0 19.3 22.3 21.2 32.7 10.8 25.8 34.1 16.1 21.2 17.8 20.8 22.0 10.4 16.9 23.5 18.0 13.0 34.4 23.7 18.2 40.0 22.6 10.6 20.1 32.9 18.1 12.4 21.0 46.6 53.6 37.2 36.6 47.0 31.9 41.7 42.6 41.3 42.3 45.9 57.9 52.2 66.2 39.4 60.4 41.5 60.4 62.1 13.4 14.3 12.7 15.4 14.5 15.0 13.3 14.1 13.4 13.8 16.2 13.2 30.1 9.6 19.2 7.8 52.7 13.3 15.1 10.7 22.2 10.4 19.1 17.9 16.1 17.2 12.7 7.3 8.4 22.9 73.5 12.7 9.8 18.0 57.0 32.0 30.1 29.1 6.7 24.4 10.7 17.1 33.7 18.2 15.8 25.2 26.6 24.3 27.8 16.8 21.9 8.4 7.3 16.4 8.2 58.2 36.1 24.5 12.5 46.9 14.2 14.0 68.4 10.9 41.2 8.5 8.3 22.5 8.7 16.6 41.3 12.6 12.2 15.2 23.2 7.7 6.6 20.5 21.8 41.8 24.8 24.9 18.5 11.8 54.5 21.6 13.6 13.2 MSMP "PC-3, PSMP" ENSG00000215183 "Microseminoprotein, prostate associated" Q1L6U9 9 35752990-35756613 "Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5;choroid plexus: 1.1;pituitary gland: 1.5;placenta: 1.2" "Group enriched" "Detected in some" 50 "Early spermatids: 96.3;Late spermatids: 216.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 85.7;PC-3: 108.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA055174 Uncertain Supported Vesicles,Cytosol "Secreted in other tissues" No No 30000 "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 34: Spermatids - Unknown function" Vesicles Cytosol "HPA055174: AB_2682726" 0.2 0.0 0.6 0.2 0.3 0.0 0.1 0.4 0.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.0 0.1 0.2 1.5 0.4 0.0 0.0 0.0 1.5 1.2 0.9 0.0 0.1 0.2 0.0 0.0 0.5 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.3 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 85.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.6 0.3 0.4 0.8 0.3 0.3 1.5 0.4 0.9 0.6 0.3 0.4 1.3 0.0 1.1 0.0 1.1 0.4 1.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 1.4 96.3 0.6 0.1 3.1 0.0 0.0 0.0 2.0 0.2 0.3 0.0 0.2 0.0 0.5 2.5 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.8 216.6 0.3 0.1 1.8 0.0 0.0 0.4 0.0 0.0 0.0 1.8 0.1 0.7 0.1 1.5 0.0 0.4 0.2 0.5 0.0 0.0 0.1 0.8 0.5 0.0 0.1 0.3 0.2 0.1 0.3 1.3 MSN ENSG00000147065 Moesin P26038 X 65588377-65741931 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 337.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047337, CAB047338" Enhanced Enhanced "Plasma membrane" NA NA 130000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010898: AB_260635, CAB047336: , CAB047337: , CAB047338: , HPA000263: AB_1856043, HPA011135: AB_1854053, HPA011227: AB_1854054" "unprognostic (1.03e-1)" "unprognostic (7.89e-2)" "unprognostic (7.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.08e-3)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (1.44e-2)" "unprognostic (3.35e-2)" "unprognostic (1.70e-2)" "unprognostic (9.04e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (5.68e-3)" "unprognostic (7.75e-2)" "unprognostic (7.21e-2)" "unprognostic (6.81e-2)" 213.3 83.3 66.6 259.8 71.4 269.8 144.6 80.0 70.9 113.9 79.6 116.0 43.9 155.8 45.0 87.9 110.0 123.1 130.2 64.8 95.9 139.7 91.8 281.5 207.5 101.9 79.6 91.9 41.0 39.2 48.2 150.6 98.8 72.5 78.4 24.0 76.0 126.6 56.2 100.7 96.6 251.6 91.8 200.0 78.4 21.9 87.3 177.0 152.5 75.7 242.2 154.8 98.0 95.5 298.3 223.2 214.0 177.9 250.6 328.9 1.9 733.9 472.2 397.3 305.5 0.6 50.9 247.7 638.8 654.4 210.3 199.4 228.5 523.4 514.1 461.7 63.0 687.5 355.0 0.6 236.0 845.3 1063.8 248.1 110.7 733.1 641.5 384.2 892.3 338.5 339.5 747.1 638.4 0.6 503.0 631.0 266.1 0.3 418.9 259.8 384.0 189.0 426.5 0.2 1.7 0.8 590.6 4.4 231.5 239.7 2.7 453.8 1426.9 449.5 285.3 613.2 494.6 268.6 438.4 262.5 328.9 1053.3 513.0 219.9 312.4 194.0 214.8 359.3 160.4 91.9 116.9 170.6 225.3 76.9 78.3 121.9 334.3 177.5 460.3 31.9 97.0 673.8 66.6 71.4 80.0 70.9 64.8 95.9 101.9 79.6 98.8 91.8 87.3 95.5 243.4 179.5 163.0 19.9 140.8 205.5 62.2 56.5 38.7 0.7 27.9 30.9 27.5 11.5 45.4 68.0 4.2 6.0 227.3 7.5 29.4 177.3 1.4 35.7 64.9 256.2 0.0 71.9 2.2 170.0 16.0 85.7 16.3 62.9 164.6 22.6 100.3 51.2 167.2 5.0 3.8 3.2 2.0 255.3 206.2 5.3 73.7 251.9 69.4 67.5 291.9 43.6 337.8 7.1 14.7 327.7 3.3 109.4 105.7 102.2 0.0 113.6 25.6 2.4 72.3 85.0 131.0 1.9 3.6 24.3 149.5 4.2 206.9 24.4 2.2 54.0 MTARC2 "FLJ20605, MARC2, MOSC2" ENSG00000117791 "Mitochondrial amidoxime reducing component 2" Q969Z3 1 220748225-220784815 "Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 132.5;liver: 223.6" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 29.0" "Cancer enhanced" "Detected in all" "liver cancer: 35.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 14.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 14.1" "Cell line enhanced" "Detected in many" "T-47d: 36.0;TIME: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015085, HPA017572" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "HPA015085: AB_1848780, HPA017572: AB_1848778" "unprognostic (8.17e-2)" "unprognostic (1.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.40e-10)" "unprognostic (4.78e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-1)" "unprognostic (1.90e-1)" "unprognostic (2.05e-2)" "prognostic favorable (3.09e-4)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (2.39e-2)" "unprognostic (6.23e-2)" 30.4 17.9 10.3 6.2 11.8 0.6 16.5 7.8 15.4 11.6 54.5 17.9 59.1 6.7 15.6 9.7 10.8 21.6 25.0 11.2 10.1 132.5 223.6 31.2 7.4 7.9 11.7 21.9 29.9 125.0 9.5 12.7 8.3 20.2 20.5 3.0 36.3 12.5 34.5 4.7 58.2 9.5 8.2 11.6 27.9 11.0 11.9 3.1 42.1 21.4 8.2 12.5 10.4 9.9 9.5 7.8 4.1 5.4 10.1 4.6 3.2 6.7 11.7 8.0 8.1 5.3 11.9 0.0 4.6 6.5 4.3 1.3 0.0 9.4 7.5 0.0 15.7 0.0 16.5 11.0 9.3 4.5 0.0 8.0 14.1 3.0 0.0 12.1 22.2 0.0 6.3 0.1 5.1 2.3 0.0 15.7 6.6 3.2 7.8 0.0 13.0 0.2 28.2 10.3 2.3 6.1 10.6 0.1 15.2 4.5 36.0 5.6 33.9 0.0 4.8 10.6 12.0 2.0 0.1 0.0 1.7 0.0 0.1 14.1 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.3 11.8 7.8 15.4 11.2 10.1 7.9 11.7 8.3 8.2 11.9 9.9 7.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.7 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 MTG1 GTPBP7 ENSG00000148824 "Mitochondrial ribosome associated GTPase 1" Q9BT17 10 133394094-133422520 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037826, HPA037827" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA037826: AB_2675692, HPA037827: AB_10670959" "unprognostic (2.94e-2)" "unprognostic (8.08e-2)" "unprognostic (5.90e-3)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-2)" "unprognostic (5.85e-2)" "unprognostic (6.20e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-1)" "prognostic favorable (5.08e-4)" "unprognostic (4.63e-3)" "prognostic unfavorable (6.79e-7)" "unprognostic (3.88e-2)" "unprognostic (5.96e-2)" "unprognostic (5.19e-2)" "prognostic favorable (1.03e-5)" 15.1 28.1 10.0 13.6 9.9 12.5 16.3 11.0 12.2 17.0 11.4 16.0 19.7 15.2 2.8 21.4 15.0 8.4 15.0 9.7 9.6 27.1 48.4 13.0 16.2 10.8 9.9 17.2 19.7 17.6 16.2 11.2 10.2 19.3 11.2 3.4 16.3 10.4 18.5 17.7 18.9 10.1 9.3 26.1 18.4 31.2 10.4 12.7 18.0 13.0 14.1 15.4 15.4 9.9 42.5 43.3 28.3 63.4 17.0 12.5 42.0 24.2 20.8 38.5 31.4 55.0 25.8 31.2 36.2 20.5 16.3 33.5 30.6 43.2 17.4 29.8 37.7 30.5 23.5 52.1 40.2 20.6 30.4 31.5 22.9 37.3 58.6 27.7 56.5 27.9 26.2 28.0 30.6 47.4 20.2 28.9 39.3 45.2 14.4 29.6 28.0 7.1 34.6 29.6 10.7 37.9 36.4 32.1 51.4 15.8 28.2 29.6 37.1 14.2 29.2 14.6 26.1 13.5 8.3 43.3 25.2 18.3 19.8 0.5 21.5 23.0 26.9 35.5 27.7 41.5 23.8 22.7 20.3 48.8 18.6 19.2 3.1 47.5 42.9 42.8 27.5 20.3 10.0 9.9 11.0 12.2 9.7 9.6 10.8 9.9 10.2 9.3 10.4 9.9 4.5 9.6 3.6 30.7 27.1 4.2 5.9 8.8 33.0 0.0 6.1 5.3 1.6 8.6 5.9 3.7 0.0 9.4 8.1 8.4 5.9 13.5 2.2 5.9 9.9 7.7 12.6 26.1 25.1 9.6 7.3 9.0 43.8 5.9 6.3 10.8 7.5 5.5 5.4 0.0 31.8 7.5 4.1 6.3 4.7 5.4 9.0 7.1 5.4 21.5 8.1 0.0 12.3 29.7 33.9 10.4 9.2 4.9 37.5 7.2 12.5 6.9 6.1 0.0 13.1 6.1 6.0 9.0 9.3 32.9 3.4 6.7 16.6 6.7 10.1 7.4 MTUS1 "ATBP, ATIP1, ATIP3, DKFZp586D1519, FLJ14295, ICIS, KIAA1288, MP44, MTSG1" ENSG00000129422 "Microtubule associated scaffold protein 1" Q9ULD2 8 17643795-17800917 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 408.9;Alveolar cells type 2: 281.0;Oligodendrocytes: 469.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.4" "Lineage enriched" "Detected in single" 19 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "A549: 115.7;AN3-CA: 100.1;HUVEC TERT2: 296.8;SK-MEL-30: 84.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067903, HPA069795" Enhanced Nucleoli,Microtubules No No "Cluster 32: T-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoli, Microtubules" "HPA067903: AB_2685921, HPA069795: AB_2686198" "unprognostic (3.20e-1)" "unprognostic (3.29e-1)" "prognostic favorable (1.05e-4)" "unprognostic (2.50e-2)" "unprognostic (2.27e-1)" "unprognostic (7.72e-3)" "unprognostic (1.36e-1)" "unprognostic (1.86e-3)" "unprognostic (2.44e-1)" "unprognostic (9.73e-2)" "unprognostic (7.93e-3)" "unprognostic (3.33e-1)" "prognostic favorable (2.76e-4)" "unprognostic (2.04e-1)" "unprognostic (2.38e-2)" "unprognostic (2.53e-3)" "unprognostic (2.43e-1)" 52.9 39.0 65.6 13.4 100.4 0.3 45.0 97.4 81.7 34.5 59.3 36.6 32.6 31.4 22.6 38.0 28.7 37.9 85.6 66.0 76.9 26.2 56.8 40.4 9.0 106.4 90.8 51.4 98.2 65.2 22.9 70.0 104.2 31.9 39.1 56.9 49.9 24.7 106.2 26.0 33.4 38.2 75.7 16.1 42.2 12.2 87.6 22.8 27.3 167.4 14.5 35.8 31.0 151.1 21.9 115.7 18.5 100.1 0.1 0.6 33.2 1.1 7.8 0.6 2.3 8.7 7.8 2.8 8.5 0.0 4.8 22.2 30.8 10.9 1.1 15.8 13.2 0.0 19.2 55.8 6.6 0.0 0.4 9.1 16.4 2.4 33.3 0.0 296.8 7.7 0.0 43.3 0.1 5.7 4.4 5.7 26.5 44.1 2.9 0.1 17.0 11.5 5.9 44.4 9.2 2.2 14.8 26.6 84.7 11.0 19.2 0.3 61.4 0.1 24.0 0.1 0.2 5.9 3.5 0.0 0.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.4 65.6 100.4 97.4 81.7 66.0 76.9 106.4 90.8 104.2 75.7 87.6 151.1 408.9 70.5 281.0 139.1 2.9 21.0 56.4 38.9 58.1 0.0 42.7 31.6 141.6 55.8 88.4 20.2 0.0 23.8 1.6 58.5 11.7 50.1 18.5 71.4 53.8 154.5 15.0 0.0 6.1 174.2 40.0 83.8 94.8 144.2 9.5 7.6 29.3 71.2 58.2 0.0 81.8 47.3 22.4 4.1 16.1 24.5 76.4 9.0 28.4 174.3 2.7 0.0 2.1 39.2 469.2 56.5 19.1 57.2 15.3 77.9 52.4 10.4 49.4 0.0 19.7 69.7 60.1 2.4 8.3 45.3 20.3 54.0 7.1 79.8 49.3 81.3 MVP "LRP, VAULT1" ENSG00000013364 "Major vault protein" Q14764 16 29820394-29848039 "Cancer-related genes, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" Ribonucleoprotein "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 504.7;Exocrine glandular cells: 310.8;Paneth cells: 338.3;Proximal enterocytes: 514.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 429.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002321, CAB002752, CAB022717, HPA064740" Enhanced Supported Cytosol NA NA 110000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB002752: , CAB022717: , HPA002321: AB_1079277, HPA064740: AB_2685342" "prognostic favorable (4.51e-4)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "unprognostic (1.80e-1)" "unprognostic (8.17e-2)" "unprognostic (3.03e-2)" "unprognostic (1.11e-2)" "unprognostic (2.22e-2)" "unprognostic (6.03e-3)" "unprognostic (2.19e-1)" "unprognostic (6.85e-3)" "unprognostic (2.86e-1)" "prognostic favorable (5.49e-5)" "unprognostic (2.22e-1)" "unprognostic (5.19e-2)" "unprognostic (5.69e-3)" "unprognostic (2.65e-2)" 84.4 181.7 26.2 96.0 35.7 46.4 71.0 29.9 33.7 76.6 32.5 165.6 154.7 73.1 14.3 75.4 73.3 74.3 64.4 26.0 31.9 113.4 66.9 121.9 71.1 43.1 36.4 103.3 101.9 18.9 47.5 38.0 35.5 59.7 96.5 6.3 77.1 38.9 50.6 61.1 158.9 69.0 32.6 114.0 107.8 39.4 42.3 31.3 60.6 32.4 47.6 80.0 72.9 38.3 64.8 191.8 0.8 1.7 212.0 275.0 25.9 163.4 258.5 88.0 121.4 24.7 216.8 3.1 134.9 231.0 108.9 78.1 0.8 129.5 42.2 166.4 1.8 3.0 81.6 87.6 190.1 2.3 60.2 366.9 96.1 207.0 58.3 170.5 274.5 6.2 0.5 92.1 167.7 18.3 0.8 4.3 2.4 93.4 11.6 2.1 0.7 32.5 229.1 114.6 10.5 7.6 41.8 53.8 31.8 6.5 9.5 18.7 429.3 124.2 59.4 119.9 62.0 66.6 45.1 2.7 294.6 4.8 24.9 50.4 140.8 56.3 70.9 214.3 55.1 36.6 80.7 73.6 113.1 27.2 59.4 54.0 160.0 73.7 204.0 69.2 90.7 164.4 26.2 35.7 29.9 33.7 26.0 31.9 43.1 36.4 35.5 32.6 42.3 38.3 34.2 48.1 115.5 9.8 31.2 19.6 39.3 120.3 16.5 4.8 17.9 10.0 12.9 82.9 112.0 69.9 2.1 113.6 31.2 504.7 45.0 272.7 4.9 43.9 25.9 40.9 56.5 8.6 3.2 310.8 71.4 52.8 120.8 65.9 33.7 14.8 36.4 23.8 78.0 8.4 3.4 177.1 95.6 41.0 27.1 21.1 57.5 55.0 32.0 9.4 223.3 3.0 59.8 0.0 23.1 278.5 338.3 47.8 36.4 25.0 514.8 194.8 110.3 4.9 19.7 23.8 51.3 2.7 1.8 20.7 21.9 264.5 45.1 24.7 206.8 56.7 MXD4 "bHLHc12, MAD4, MST149, MSTP149" ENSG00000123933 "MAX dimerization protein 4" Q14582 4 2247432-2262109 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 169.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053363 Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA053363: AB_2682128" "unprognostic (1.26e-1)" "unprognostic (1.09e-1)" "unprognostic (2.37e-2)" "unprognostic (2.84e-2)" "unprognostic (3.54e-2)" "prognostic favorable (2.21e-5)" "unprognostic (1.64e-1)" "unprognostic (5.94e-2)" "unprognostic (8.37e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.39e-5)" "unprognostic (5.65e-2)" "unprognostic (1.09e-3)" "unprognostic (2.13e-1)" "unprognostic (1.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.12e-2)" 38.6 42.0 43.9 11.3 39.8 29.8 35.9 62.1 58.4 31.1 38.2 35.2 18.3 37.1 11.6 21.0 27.9 15.1 36.2 40.9 37.7 38.8 20.6 38.5 20.2 40.6 40.5 23.2 25.3 12.4 63.5 14.3 39.7 33.0 7.2 5.9 35.0 25.0 24.1 25.9 28.6 14.0 37.5 57.6 31.2 22.1 41.2 23.2 33.4 14.4 9.1 25.1 19.4 39.6 2.3 8.3 12.9 15.5 44.2 32.6 3.0 16.4 16.6 12.0 12.2 2.0 7.1 7.1 36.1 25.0 6.4 11.2 3.7 13.0 3.1 6.3 39.5 1.3 29.0 23.6 32.4 5.5 14.5 51.1 22.9 3.9 6.1 26.5 28.9 10.3 9.8 11.6 11.3 16.2 12.6 31.6 5.1 9.6 36.4 8.5 4.4 15.1 14.2 13.0 20.8 38.7 15.4 7.5 12.3 15.7 35.2 34.4 68.7 13.3 5.3 9.9 3.7 17.6 13.2 2.8 18.2 4.9 4.0 7.2 2.7 3.4 3.3 3.0 2.7 2.2 3.0 3.3 2.5 2.0 1.5 1.5 1.1 2.0 3.0 7.2 4.0 1.4 43.9 39.8 62.1 58.4 40.9 37.7 40.6 40.5 39.7 37.5 41.2 39.6 169.7 19.2 19.9 48.0 37.9 19.1 15.3 13.6 7.4 81.6 67.8 67.1 18.4 17.2 16.1 60.7 87.6 44.3 129.6 47.9 15.6 16.5 10.1 39.6 81.9 54.7 33.6 20.6 11.6 18.3 48.4 53.6 23.0 42.8 24.1 37.9 103.5 35.5 50.3 65.6 20.5 55.9 10.2 72.9 27.5 28.8 33.2 58.8 23.2 27.2 21.6 67.9 68.0 19.1 19.7 17.5 31.8 56.4 54.0 28.7 44.0 22.1 13.4 97.1 26.3 39.6 48.5 7.0 37.0 17.3 26.3 32.7 54.7 100.5 38.2 13.1 MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697895-152724567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.6" "Group enriched" "Detected in some" 5 "Adipocytes: 123.0;Endothelial cells: 141.3;Hepatic stellate cells: 230.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 248 "granulocytes: 30.7" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 124.6;TIME: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Approved Nucleoplasm,Vesicles NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" 26.6 3.2 6.8 5.2 6.9 1.2 21.4 6.9 10.2 9.0 5.2 6.1 3.5 10.1 4.5 4.6 9.2 10.5 17.1 6.3 7.1 6.6 13.1 15.6 6.2 7.7 6.9 3.6 2.7 4.3 2.2 20.7 8.6 4.4 5.8 1.0 3.7 3.8 12.8 4.7 5.6 12.4 6.8 49.6 4.5 1.8 10.0 2.5 12.2 20.5 3.0 8.1 7.3 7.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 17.7 0.1 0.0 0.2 0.0 0.1 0.0 23.0 0.3 0.0 0.7 0.1 0.1 0.0 0.2 0.2 0.3 0.0 124.6 0.0 0.3 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 104.4 0.5 0.8 1.5 0.0 1.1 0.0 15.6 0.0 0.0 0.0 0.9 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.6 6.8 6.9 6.9 10.2 6.3 7.1 7.7 6.9 8.6 6.8 10.0 7.5 123.0 0.0 5.2 0.7 0.8 7.1 0.2 0.1 2.8 0.2 0.4 0.9 3.1 2.8 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 1.3 0.2 141.3 0.0 13.7 0.1 0.2 0.0 4.0 0.0 0.1 1.3 0.0 230.6 2.1 0.1 0.0 0.1 0.0 0.0 7.3 7.3 3.7 0.3 13.3 14.2 30.9 0.1 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.5 0.0 0.0 17.7 0.0 0.0 1.5 2.2 0.1 0.1 0.5 5.5 0.0 0.9 0.5 0.0 0.7 MYL12B MRLC2 ENSG00000118680 "Myosin light chain 12B" O14950 18 3261479-3278461 "Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039262, HPA045244, HPA059197" Supported NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (2.55e-2)" "unprognostic (7.31e-2)" "unprognostic (5.69e-2)" "unprognostic (4.05e-2)" "unprognostic (3.66e-1)" "unprognostic (2.85e-3)" "unprognostic (1.38e-2)" "unprognostic (7.65e-2)" "unprognostic (2.89e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (9.69e-4)" "unprognostic (1.18e-1)" "prognostic favorable (8.17e-5)" "unprognostic (3.38e-1)" "unprognostic (3.77e-1)" "prognostic favorable (6.62e-6)" "unprognostic (1.27e-2)" 360.1 441.4 172.7 232.6 179.2 301.8 377.8 181.2 233.2 317.9 206.8 436.4 420.1 265.9 482.9 509.1 297.0 278.9 312.6 185.2 186.5 559.9 406.1 426.9 272.3 186.2 180.1 231.7 224.3 418.7 189.7 405.2 184.9 244.1 439.6 103.9 364.9 273.0 269.7 342.1 403.5 248.4 180.4 274.1 321.4 152.9 183.3 303.8 340.5 214.7 314.8 404.3 347.9 181.5 565.6 294.1 253.8 247.3 726.9 598.1 437.1 839.9 719.9 751.9 769.3 611.7 439.0 282.5 360.1 1154.6 576.7 277.3 424.3 967.7 748.6 166.1 180.7 285.0 297.2 482.8 744.0 645.0 428.0 533.6 879.0 512.7 320.4 659.9 1128.1 283.3 247.8 266.3 971.9 1146.7 372.0 450.3 170.1 666.5 249.7 181.0 320.2 228.5 1572.8 995.6 208.1 217.4 836.3 497.2 524.7 403.6 429.2 379.3 1422.8 736.3 1111.3 654.0 1036.9 148.1 153.2 342.8 448.2 256.9 586.8 1484.7 500.6 1513.2 643.7 666.4 548.3 436.8 619.3 701.5 582.0 360.0 501.2 582.5 1141.6 485.2 799.0 797.2 742.7 1294.1 172.7 179.2 181.2 233.2 185.2 186.5 186.2 180.1 184.9 180.4 183.3 181.5 846.5 807.7 516.2 16.3 279.4 634.5 889.6 2141.6 412.6 82.6 394.7 556.9 755.3 444.7 1157.4 542.6 25.0 1084.6 470.9 1301.7 1048.7 1453.7 164.3 617.3 362.5 674.4 243.9 269.7 21.9 1470.9 1082.5 447.4 290.0 705.2 446.8 372.9 683.9 292.2 614.1 65.6 20.4 590.3 990.7 375.7 450.1 225.0 446.4 448.1 345.1 52.5 911.6 185.7 461.4 14.1 21.6 2199.0 1180.2 433.3 121.6 814.9 1459.2 1477.9 891.9 94.5 355.0 269.5 542.6 240.0 208.9 486.5 568.4 1402.6 532.9 671.1 568.9 1097.6 MYOF "FER1L3, KIAA1207" ENSG00000138119 Myoferlin Q9NZM1 10 93306429-93482334 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 123.4;Pancreatic endocrine cells: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.4;non-classical monocyte: 26.6" "Group enriched" "Detected in many" 57 "dendritic cells: 8.1;monocytes: 26.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 452.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014245 Enhanced Supported "Vesicles,Plasma membrane" NA NA 190000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "Plasma membrane" "HPA014245: AB_1848495" "unprognostic (3.41e-2)" "unprognostic (3.85e-1)" "unprognostic (2.88e-2)" "unprognostic (7.44e-2)" "unprognostic (3.50e-2)" "unprognostic (8.57e-3)" "unprognostic (3.48e-2)" "unprognostic (7.75e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.55e-1)" "unprognostic (5.74e-3)" "unprognostic (1.87e-1)" "unprognostic (1.94e-2)" "unprognostic (9.17e-2)" "unprognostic (9.18e-2)" 31.7 8.1 2.9 20.6 4.1 1.5 43.3 5.0 2.5 56.4 37.4 22.4 5.3 27.5 7.1 36.4 36.9 26.6 13.8 3.4 4.1 10.9 2.9 32.2 4.4 8.9 6.8 9.8 5.9 23.8 3.8 55.2 8.1 27.5 29.3 0.9 19.7 31.4 3.6 56.1 9.0 44.3 6.2 6.5 13.4 2.2 5.4 5.1 35.7 6.2 9.1 62.0 29.4 6.2 228.9 206.3 21.4 14.6 159.4 318.4 62.0 190.3 452.7 110.1 109.2 51.1 177.1 0.0 76.9 353.7 116.2 350.0 1.8 204.7 82.6 1.4 0.9 0.0 80.8 2.1 55.2 0.0 0.2 183.0 71.6 77.7 323.8 289.4 299.7 0.0 0.0 0.5 275.6 39.4 0.1 0.9 1.6 72.0 171.6 0.0 15.8 0.1 314.3 281.5 0.1 0.0 130.4 29.7 46.1 83.1 141.5 4.7 378.5 167.3 11.8 111.3 113.9 0.2 0.3 0.3 128.2 2.6 201.0 0.0 5.4 0.0 0.0 20.4 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.3 0.0 26.6 2.8 0.2 1.6 2.9 4.1 5.0 2.5 3.4 4.1 8.9 6.8 8.1 6.2 5.4 6.2 42.5 60.9 52.5 1.6 1.2 23.7 63.0 101.4 39.3 0.1 48.4 34.3 9.2 14.3 91.5 22.0 0.0 56.6 3.8 74.1 1.9 54.8 0.6 50.9 45.9 28.8 1.8 0.0 2.7 33.7 23.7 38.1 23.0 123.4 1.3 1.7 35.7 0.4 22.9 0.0 0.8 29.6 42.7 29.2 20.2 0.6 5.9 28.5 8.8 60.0 12.8 0.1 0.0 2.0 0.7 153.7 22.2 9.1 0.8 86.7 0.6 1.5 60.7 0.8 6.6 15.9 39.6 0.1 0.3 53.4 30.7 51.2 1.9 8.3 18.7 100.7 NADSYN1 FLJ10631 ENSG00000172890 "NAD synthetase 1" Q6IA69 11 71453109-71524107 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017798, HPA038523, HPA038524" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "Golgi apparatus, Cytosol" "CAB017798: , HPA038523: AB_2676060, HPA038524: AB_2676061" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" "unprognostic (7.30e-2)" "unprognostic (2.63e-3)" "unprognostic (1.75e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.17e-6)" "unprognostic (1.19e-2)" "unprognostic (4.38e-2)" "unprognostic (1.41e-1)" "unprognostic (9.41e-2)" "unprognostic (1.99e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (4.12e-3)" "unprognostic (1.38e-1)" "unprognostic (1.54e-2)" "prognostic favorable (5.10e-4)" 29.5 34.1 18.8 24.1 20.4 67.6 26.2 18.5 21.2 30.4 20.3 48.6 39.5 26.0 24.2 56.3 31.2 25.8 20.3 17.8 18.3 33.2 49.8 35.3 33.3 22.4 19.6 27.6 29.5 13.4 36.0 16.5 21.0 45.3 36.0 6.9 32.9 22.8 11.0 31.1 51.1 19.3 18.8 58.4 34.3 25.6 21.7 27.9 31.8 5.1 28.2 43.4 33.4 24.4 15.9 37.8 12.0 21.6 35.0 50.6 32.4 29.7 27.2 15.4 17.0 32.4 25.7 13.4 33.1 35.3 20.7 55.2 15.9 42.6 8.2 27.9 12.8 22.2 27.6 36.3 43.3 45.1 40.9 72.0 65.8 19.9 17.8 34.9 54.6 24.2 11.9 18.5 21.9 49.7 22.4 29.9 7.0 69.6 21.3 27.5 37.2 13.5 37.8 72.1 8.9 12.7 21.2 27.9 56.0 17.9 24.9 24.4 66.2 16.7 14.2 30.9 11.8 24.3 11.0 11.7 29.9 25.6 12.0 6.1 28.0 17.3 15.3 25.0 12.7 12.2 13.5 13.8 31.1 9.2 8.8 11.4 17.7 16.3 22.6 23.0 17.7 21.4 18.8 20.4 18.5 21.2 17.8 18.3 22.4 19.6 21.0 18.8 21.7 24.4 12.6 22.4 32.3 4.2 24.0 6.2 17.8 18.4 26.2 7.8 13.5 10.9 8.3 12.8 19.8 11.0 4.2 17.4 27.3 65.3 3.9 16.5 22.6 21.1 11.1 15.6 23.4 20.2 5.1 17.3 14.5 12.8 51.0 19.7 22.1 23.1 13.9 16.7 20.1 13.5 5.8 30.3 16.2 23.2 18.5 60.9 9.3 25.4 8.8 8.4 25.8 5.9 29.9 7.5 18.5 20.0 55.8 10.1 18.0 17.9 73.3 16.2 16.5 7.3 13.1 9.6 9.8 15.9 5.0 38.3 12.8 17.2 22.3 17.1 43.7 24.2 NALCN "bA430M15.1, CanIon, VGCNL1" ENSG00000102452 "Sodium leak channel, non-selective" Q8IZF0 13 101053776-101416508 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.1" "Group enriched" "Detected in some" 10 "Astrocytes: 125.4;Excitatory neurons: 265.8;Inhibitory neurons: 277.4;Oligodendrocyte precursor cells: 324.7;Oligodendrocytes: 477.4" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.6" "Cell line enhanced" "Detected in many" "HaCaT: 14.2;HHSteC: 14.4;hTERT-RPE1: 11.0;TIME: 19.8;U-87 MG: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031889, HPA031890, HPA031958" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA031889: AB_10669638, HPA031890: AB_10696056, HPA031958: AB_10601039" "unprognostic (4.66e-1)" "unprognostic (6.55e-3)" "unprognostic (1.86e-3)" "unprognostic (6.78e-3)" "unprognostic (1.16e-1)" "unprognostic (1.37e-3)" "unprognostic (8.11e-2)" "unprognostic (2.60e-1)" "unprognostic (7.72e-2)" "unprognostic (5.92e-2)" "unprognostic (1.25e-1)" "unprognostic (2.18e-1)" "unprognostic (1.58e-5)" "unprognostic (1.77e-3)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" 0.5 4.3 7.5 0.4 9.8 0.6 2.7 6.4 10.3 1.5 0.0 0.4 0.6 0.5 1.5 0.2 1.0 2.3 3.3 8.6 10.2 0.3 1.2 1.1 0.3 8.2 5.8 2.8 1.3 2.9 6.8 3.0 7.0 0.3 0.6 6.1 0.8 1.0 0.3 0.5 0.5 0.5 6.8 0.4 0.7 0.6 8.3 0.0 2.4 0.2 0.1 0.5 0.2 13.1 0.1 7.8 1.4 0.2 0.7 0.3 0.1 0.8 0.8 1.8 0.4 0.2 8.9 0.0 0.3 3.6 0.8 14.2 0.0 2.2 5.5 0.0 1.2 0.4 3.8 0.1 14.4 0.2 0.3 0.4 0.5 1.7 4.6 11.0 8.2 0.1 0.1 0.4 5.9 0.0 0.1 0.0 0.4 1.3 1.8 0.0 0.0 0.0 4.6 1.9 1.2 0.6 0.1 0.0 0.8 0.9 0.2 0.1 19.8 0.4 0.1 0.3 1.8 0.1 0.1 0.1 11.4 0.1 0.3 2.6 0.1 0.2 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 0.5 0.2 0.1 0.2 0.1 0.1 7.5 9.8 6.4 10.3 8.6 10.2 8.2 5.8 7.0 6.8 8.3 13.1 0.1 0.0 0.0 125.4 0.0 0.3 0.0 0.3 0.6 15.4 3.5 4.6 6.2 0.0 0.1 0.0 6.2 1.0 0.0 0.0 0.0 0.8 4.5 0.1 0.2 0.6 0.0 0.0 265.8 0.2 0.2 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 26.9 277.4 0.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 23.4 0.0 2.0 0.0 324.7 477.4 0.3 0.0 1.9 0.0 0.0 0.0 0.1 0.0 2.6 0.0 3.6 0.5 0.2 0.8 0.0 0.1 0.5 0.0 0.1 0.0 0.0 NAV1 "DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1" ENSG00000134369 "Neuron navigator 1" Q8NEY1 1 201622885-201826969 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 169.1;Inhibitory neurons: 161.7;Oligodendrocyte precursor cells: 713.8;Oligodendrocytes: 224.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.4;myeloid DC: 2.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2.1;granulocytes: 3.4" "Cell line enhanced" "Detected in many" "TIME: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012302, HPA018127, HPA027887" Enhanced Approved Microtubules NA NA "Cluster 46: Basophils - DNA binding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Microtubules "CAB012302: AB_776716, HPA018127: AB_1854317, HPA027887: AB_10601040" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (4.12e-2)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-1)" "unprognostic (1.79e-1)" "unprognostic (3.45e-1)" "unprognostic (9.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.68e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (3.45e-2)" "unprognostic (2.16e-1)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" 19.6 2.7 17.4 8.2 18.3 1.6 15.2 8.0 17.7 11.7 0.0 12.3 3.7 10.1 4.3 8.6 7.2 7.5 26.6 17.5 20.3 4.6 1.9 11.1 4.1 24.6 17.9 3.7 4.4 5.2 5.2 11.8 15.1 7.5 5.4 5.4 7.8 6.7 4.8 7.7 6.2 10.3 9.9 3.6 5.3 4.4 21.8 2.8 9.4 6.7 3.7 14.9 12.6 32.5 1.6 2.9 29.0 3.8 84.3 69.5 51.7 44.6 43.0 35.5 30.9 0.0 15.7 0.6 0.7 61.4 19.4 21.5 22.0 14.9 28.4 2.5 3.2 1.4 5.6 0.0 22.5 0.2 19.1 30.6 5.4 62.4 36.0 94.9 80.7 1.8 0.8 2.6 29.8 0.4 0.0 0.1 42.4 0.7 1.7 3.9 65.0 9.3 4.8 4.3 21.9 4.5 11.1 47.6 14.5 19.2 0.4 1.2 187.8 54.5 11.1 54.7 39.4 8.1 2.3 0.2 59.2 5.9 47.5 3.4 0.5 0.1 0.2 0.3 0.1 0.3 0.2 0.0 2.1 0.3 0.2 0.1 0.0 0.1 0.3 0.5 0.0 0.3 17.4 18.3 8.0 17.7 17.5 20.3 24.6 17.9 15.1 9.9 21.8 32.5 77.4 3.2 1.5 169.1 3.1 11.0 2.2 5.9 8.0 34.6 4.8 4.3 29.2 1.5 4.8 12.9 0.0 14.9 0.9 4.7 0.0 13.0 3.6 1.6 6.4 39.3 52.8 1.7 98.2 8.3 54.1 45.8 8.2 4.4 17.7 54.5 21.0 0.7 14.5 25.2 161.7 3.4 6.1 18.3 15.8 3.8 10.8 15.1 23.2 69.3 60.6 11.8 1.0 713.8 224.6 21.7 4.2 0.7 4.9 2.3 0.9 0.6 3.5 4.0 6.6 119.3 18.8 0.6 2.6 16.9 7.0 15.7 2.0 6.6 5.0 3.2 NBPF14 DJ328E19.C1.1 ENSG00000270629 "NBPF member 14" 1 148531385-148679742 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 89.8;Astrocytes: 95.0;Paneth cells: 174.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 128.6" "HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol Microtubules "HPA038748: AB_2676188, HPA038752: , HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (5.28e-2)" "unprognostic (3.88e-2)" "unprognostic (7.92e-3)" "unprognostic (7.13e-2)" "unprognostic (2.46e-1)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (2.02e-2)" "unprognostic (7.69e-4)" "unprognostic (7.23e-3)" "unprognostic (5.20e-2)" "unprognostic (5.15e-4)" "unprognostic (2.28e-2)" "unprognostic (2.61e-1)" "unprognostic (3.73e-1)" "unprognostic (2.52e-2)" 31.3 10.3 18.1 26.1 16.8 44.2 26.1 11.0 31.9 21.4 40.8 19.6 9.1 29.4 22.4 24.2 22.5 19.9 9.3 23.5 12.1 13.9 21.2 22.1 22.2 21.2 17.3 45.2 26.9 18.4 3.9 15.7 14.4 19.3 20.1 26.1 16.3 14.7 13.6 51.8 11.3 27.5 10.4 31.9 11.4 23.6 25.1 16.3 16.5 12.2 18.6 16.6 15.7 20.7 80.9 12.9 30.7 21.1 64.1 90.4 14.4 26.5 25.4 16.9 20.2 11.5 21.3 16.0 6.6 32.0 25.1 23.7 20.0 26.4 29.4 29.4 21.3 36.5 47.1 2.3 22.8 30.9 14.9 83.2 23.9 55.7 58.5 97.3 29.2 11.5 13.9 50.8 43.8 44.2 7.8 20.8 13.1 14.8 31.4 11.7 25.4 39.8 17.9 34.0 0.4 0.5 54.4 28.6 15.6 30.2 36.7 26.7 128.6 23.4 23.2 22.9 50.1 41.7 16.2 35.5 39.1 27.0 31.1 11.9 16.2 15.2 2.0 8.3 1.0 11.8 1.5 1.3 4.5 11.3 2.0 1.8 34.9 2.4 15.6 17.7 1.8 1.7 18.1 16.8 11.0 31.9 23.5 12.1 21.2 17.3 14.4 10.4 25.1 20.7 2.9 89.8 83.7 95.0 34.8 2.2 47.3 0.6 10.8 2.0 16.9 9.3 20.2 11.5 15.2 12.9 4.2 1.3 28.1 10.7 0.0 37.4 47.3 11.4 8.5 3.7 3.6 15.5 3.7 16.2 14.0 31.8 6.1 20.0 53.7 21.2 3.3 9.9 13.7 0.0 4.4 7.4 0.0 45.3 3.4 43.8 28.3 49.6 1.8 17.8 61.8 13.3 6.2 28.1 0.7 26.4 174.5 17.0 13.3 22.2 6.9 8.6 9.1 9.8 13.1 14.0 18.1 47.5 13.0 38.2 6.3 1.5 12.4 8.4 21.0 41.3 NCOA4 "ARA70, DKFZp762E1112, ELE1, PTC3, RFG" ENSG00000266412 "Nuclear receptor coactivator 4" Q13772 10 46005088-46030623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 476.2;Macrophages: 316.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 251.9;granulocytes: 839.6;monocytes: 363.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051260, HPA065208" Uncertain Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Nucleoli "Golgi apparatus, Cytosol" "HPA051260: AB_2681412, HPA065208: AB_2685432" "unprognostic (4.23e-2)" "unprognostic (1.50e-1)" "unprognostic (2.44e-2)" "unprognostic (1.82e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.34e-1)" "unprognostic (1.80e-1)" "unprognostic (9.34e-2)" "unprognostic (4.67e-2)" "unprognostic (5.22e-2)" "unprognostic (9.16e-2)" "unprognostic (2.04e-2)" "prognostic favorable (8.04e-6)" "unprognostic (1.35e-1)" "unprognostic (4.71e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" 117.1 67.8 45.6 91.5 52.5 189.5 96.9 56.1 50.9 85.1 50.7 110.3 249.7 70.2 74.6 110.3 62.6 87.8 156.8 40.6 55.8 159.7 372.9 108.3 102.6 52.4 53.5 65.5 64.6 97.9 25.2 131.3 53.6 132.2 115.7 33.7 79.2 78.7 163.5 71.1 155.9 98.3 52.6 148.1 90.3 43.6 51.6 124.4 87.0 193.6 150.3 104.6 46.8 60.0 142.7 58.5 68.0 70.4 176.9 159.4 170.3 128.3 204.8 122.1 119.6 91.0 102.3 161.2 149.2 211.2 69.1 141.8 72.6 142.3 137.1 114.4 74.1 108.4 74.3 263.5 124.0 279.9 229.7 156.1 139.2 104.2 175.7 131.6 185.5 79.5 119.7 93.5 171.9 64.0 136.1 104.3 41.4 110.2 34.8 79.5 99.3 96.7 148.9 119.4 68.2 46.1 128.9 146.2 131.5 133.5 105.7 135.3 171.6 75.8 89.9 81.3 87.5 69.3 79.1 156.9 94.6 231.2 41.2 692.1 363.6 611.8 78.9 223.6 86.2 57.6 73.3 74.9 251.9 53.8 78.2 66.4 839.6 119.0 275.3 77.4 92.8 559.4 45.6 52.5 56.1 50.9 40.6 55.8 52.4 53.5 53.6 52.6 51.6 60.0 44.5 51.3 95.2 13.4 44.6 49.5 39.3 126.2 50.7 14.3 49.6 38.5 161.3 45.8 96.2 44.1 29.2 104.7 58.2 108.8 80.3 45.3 105.4 45.1 37.7 52.9 26.9 476.2 17.4 51.8 107.2 45.3 42.3 56.9 195.2 28.2 55.3 166.7 181.4 20.2 20.5 45.4 59.0 254.5 74.2 72.4 37.3 316.1 51.6 16.9 158.4 38.2 44.3 18.6 22.9 47.8 63.9 47.4 37.6 62.0 162.5 128.8 59.7 13.0 13.1 36.7 46.7 24.5 16.5 71.9 56.7 158.2 41.3 60.7 71.3 52.0 NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 29.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1968.8;Inhibitory neurons: 1254.4;Oligodendrocyte precursor cells: 726.3;Oligodendrocytes: 442.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.7;TIME: 28.5;U-2 OS: 22.9;U-251 MG: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 380000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Actin filaments, Cytosol" "HPA011894: AB_1854363" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (7.99e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.15e-2)" "unprognostic (8.73e-2)" "unprognostic (3.38e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-5)" "unprognostic (5.89e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-3)" "unprognostic (2.11e-4)" 16.5 5.8 12.8 3.6 15.9 1.2 5.9 4.4 15.7 7.1 0.0 17.5 2.7 5.2 4.1 10.5 7.2 10.7 11.2 15.1 9.1 6.8 0.3 5.5 1.6 1.9 5.6 6.0 4.5 0.7 3.9 2.9 2.7 7.3 7.8 29.8 2.4 5.4 3.3 5.8 5.1 6.4 3.7 0.6 7.4 3.2 12.4 5.6 3.5 5.1 0.8 13.3 6.6 6.5 0.4 0.1 0.8 0.2 26.7 21.0 0.2 19.4 7.2 10.4 12.7 0.1 0.2 0.3 0.1 21.5 0.2 0.6 0.0 0.0 22.4 0.2 0.1 0.1 3.4 0.1 2.2 0.2 0.4 10.2 0.1 8.9 1.5 15.4 12.5 0.3 0.1 0.8 19.5 0.1 0.2 0.2 3.2 0.3 11.0 13.7 20.4 0.3 1.7 0.3 1.5 1.7 6.8 0.1 0.0 0.4 0.1 0.3 28.5 2.3 22.9 0.9 24.5 0.4 0.2 0.1 5.2 13.0 8.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 12.8 15.9 4.4 15.7 15.1 9.1 1.9 5.6 2.7 3.7 12.4 6.5 6.0 0.0 0.5 170.7 0.0 5.0 0.6 0.1 0.0 51.4 0.2 0.5 4.2 1.5 2.5 0.0 27.1 0.0 4.4 0.1 0.0 2.4 6.2 0.1 1.3 2.6 0.0 0.8 1968.8 0.0 0.0 88.7 0.5 0.1 0.0 0.2 0.0 0.0 0.2 1.7 1254.4 0.6 0.0 0.0 16.7 12.5 210.3 2.4 8.8 58.1 3.1 12.2 0.0 726.3 442.7 0.5 0.0 44.8 0.5 1.3 0.0 1.5 7.1 58.7 32.9 8.3 8.5 0.7 2.5 0.3 3.4 0.0 1.1 0.2 0.1 0.7 NHSL1 "bA43P8.1, C6orf63, KIAA1357" ENSG00000135540 "NHS like 1" Q5SYE7 6 138422043-138692571 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.2" "Cell type enriched" "Detected in many" 4 "Astrocytes: 502.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.6;non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 46.2;TIME: 64.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029966, HPA029967" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear membrane" Nucleoplasm "HPA029966: AB_10601972, HPA029967: AB_2673271" "unprognostic (1.85e-1)" "unprognostic (9.71e-2)" "unprognostic (6.19e-2)" "unprognostic (1.81e-1)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (3.27e-1)" "unprognostic (8.34e-2)" "unprognostic (5.21e-2)" "unprognostic (9.99e-2)" "unprognostic (1.10e-1)" "unprognostic (8.00e-2)" "unprognostic (4.19e-2)" "unprognostic (3.73e-2)" "unprognostic (1.52e-1)" "unprognostic (6.55e-2)" "unprognostic (4.06e-2)" 4.1 1.2 15.7 2.4 14.1 0.3 2.5 9.7 8.5 2.4 16.6 13.2 15.8 1.2 4.6 10.4 1.0 3.0 15.7 14.6 11.2 5.8 14.8 12.8 1.0 16.2 15.9 0.5 3.3 2.1 1.1 4.3 10.7 0.8 11.4 2.6 3.5 0.5 0.5 11.4 23.2 3.2 9.2 2.6 7.8 0.4 14.4 0.6 1.4 0.8 2.1 2.7 4.5 5.6 5.5 4.7 32.8 13.8 9.4 11.4 12.2 4.8 2.3 1.7 1.6 6.2 3.1 0.0 6.0 4.1 3.1 12.3 20.0 12.5 0.9 0.4 13.4 3.4 2.2 46.2 13.8 12.4 2.3 16.7 7.0 0.9 14.1 1.8 23.3 1.9 0.0 1.8 7.2 10.7 1.3 1.0 13.1 3.1 8.8 14.1 3.4 1.0 11.2 13.7 12.4 0.0 5.1 10.3 33.4 21.5 3.3 3.9 64.3 4.6 4.5 4.6 13.3 1.2 2.7 0.0 0.4 5.0 25.5 0.4 1.2 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 0.2 15.7 14.1 9.7 8.5 14.6 11.2 16.2 15.9 10.7 9.2 14.4 5.6 6.2 60.9 66.9 502.1 0.5 42.8 3.1 6.6 4.0 0.6 4.1 6.0 22.7 15.7 9.9 29.5 29.2 14.2 0.1 84.1 9.8 3.7 1.1 19.0 1.8 9.3 20.3 2.7 3.3 3.6 3.5 15.6 16.8 16.9 8.8 1.5 26.4 38.1 4.5 37.0 2.9 32.3 6.1 9.4 7.1 0.4 0.6 7.5 21.4 104.0 0.6 15.4 0.0 79.9 2.3 3.9 43.0 0.0 0.1 5.4 87.3 15.8 22.0 1.4 6.6 2.3 4.7 0.0 1.1 7.7 49.2 43.4 1.8 0.8 45.4 10.5 NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 93.6;Hepatocytes: 141.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 14.5;eosinophil: 13.6;gdT-cell: 11.0;MAIT T-cell: 19.8;memory CD4 T-cell: 17.5;memory CD8 T-cell: 12.9;naive CD4 T-cell: 21.8;naive CD8 T-cell: 14.5;NK-cell: 20.8;T-reg: 29.5" "Group enriched" "Detected in many" 8 "granulocytes: 14.5;NK-cells: 20.8;T-cells: 29.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 102.6;TIME: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" 25.9 4.4 7.3 6.1 8.7 3.7 17.5 12.2 10.0 9.8 4.0 8.8 6.6 12.7 3.5 7.0 8.3 7.0 8.7 7.0 4.9 9.4 16.8 6.3 8.9 5.0 7.6 15.4 5.6 16.5 5.5 4.4 5.1 9.0 9.2 7.0 5.2 7.7 8.3 10.1 10.9 10.5 4.3 9.4 7.9 13.4 9.1 27.0 5.9 8.5 8.0 8.6 7.9 7.3 8.8 11.3 12.7 9.3 33.7 35.9 2.3 18.8 15.3 17.0 23.0 10.9 38.7 0.4 12.7 102.6 46.6 10.6 11.4 10.7 28.3 11.7 13.9 23.4 5.4 15.2 22.4 1.7 84.0 31.9 10.8 23.8 7.2 62.2 65.8 16.3 11.2 1.5 63.7 10.9 18.3 4.4 9.3 10.0 10.5 13.6 18.5 1.8 12.6 1.8 3.9 14.4 22.8 3.7 6.3 10.5 11.7 7.3 147.1 16.7 24.4 75.0 13.7 13.0 14.3 1.0 20.7 6.3 12.4 14.5 0.5 13.6 11.0 0.7 19.8 2.2 17.5 12.9 0.5 2.5 21.8 14.5 1.9 20.8 0.8 0.5 29.5 6.5 7.3 8.7 12.2 10.0 7.0 4.9 5.0 7.6 5.1 4.3 9.1 7.3 52.5 9.6 8.8 25.1 16.0 16.6 23.4 8.3 7.4 20.6 14.7 13.1 13.5 57.2 10.9 27.6 4.2 1.3 16.9 32.8 9.8 33.9 6.6 4.7 20.5 21.7 18.0 15.1 39.6 19.5 3.0 16.3 9.2 10.3 93.6 13.2 25.4 141.9 2.8 20.2 30.1 11.4 4.1 7.9 7.1 14.5 21.8 5.8 12.4 17.8 10.1 12.9 40.2 12.5 15.3 27.1 15.9 20.7 10.0 17.9 38.4 63.2 5.3 17.2 0.0 13.4 21.0 8.1 46.8 6.8 14.8 2.6 33.9 11.0 18.1 16.7 NOS3 "ECNOS, eNOS" ENSG00000164867 "Nitric oxide synthase 3" P29474 7 150991017-151014588 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 62.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.4;Early spermatids: 81.9;Endothelial cells: 32.6;Hepatic stellate cells: 29.3;Late spermatids: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "BEWO: 23.1;HUVEC TERT2: 44.7;K-562: 16.6;TIME: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002168 Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002168: AB_564072" "unprognostic (6.53e-2)" "unprognostic (3.36e-1)" "unprognostic (1.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (6.97e-2)" "unprognostic (2.56e-1)" "unprognostic (9.40e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" 19.3 6.3 8.4 5.8 6.8 0.8 13.2 5.7 6.7 7.3 3.4 5.9 2.6 9.7 0.4 5.8 8.1 4.7 20.6 5.7 6.1 24.2 4.3 11.2 2.7 9.2 7.7 3.2 2.9 1.2 7.2 4.8 8.6 7.6 1.2 0.8 4.4 1.7 3.9 4.2 6.7 3.7 7.5 62.4 5.4 7.2 11.0 0.6 9.1 3.5 1.2 9.7 7.4 6.0 0.4 0.1 1.3 4.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.3 2.2 0.4 2.1 0.0 0.2 0.7 0.0 0.1 0.0 0.0 0.4 2.2 0.3 6.4 0.6 0.5 10.4 0.1 0.2 0.0 0.0 0.1 44.7 5.1 16.6 3.6 0.0 0.0 0.2 0.5 1.7 0.7 0.1 3.0 0.0 1.8 0.0 0.3 0.5 0.4 0.2 1.4 0.0 0.4 0.1 1.4 82.5 0.2 0.7 0.4 0.1 2.4 8.9 2.2 0.0 7.5 0.0 0.2 0.1 0.1 1.1 0.2 0.7 0.3 1.7 0.9 0.2 0.5 2.3 0.9 0.3 0.2 0.2 0.2 2.1 0.5 8.4 6.8 5.7 6.7 5.7 6.1 9.2 7.7 8.6 7.5 11.0 6.0 20.4 9.6 2.2 0.3 0.7 0.9 0.1 0.1 0.0 0.2 0.2 0.3 3.1 0.0 0.7 0.0 0.0 0.2 0.7 0.1 0.0 1.0 81.9 4.9 0.7 32.6 0.0 0.0 0.2 0.0 0.1 2.9 0.5 3.2 5.7 0.7 29.3 0.7 0.4 0.0 0.2 0.4 0.0 0.6 0.5 29.3 0.9 0.4 0.0 7.5 0.0 0.3 0.0 0.0 0.0 0.8 0.0 1.2 1.5 0.4 0.1 0.2 2.2 0.3 0.0 0.6 2.6 6.9 5.3 0.2 0.6 3.6 1.6 0.9 0.1 0.9 NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Human disease related genes, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7" "Cell type enhanced" "Detected in some" "Adipocytes: 39.4;Bipolar cells: 56.7;Endothelial cells: 32.0;Excitatory neurons: 21.8;Hepatic stellate cells: 42.5;Horizontal cells: 21.9;Inhibitory neurons: 20.9" "Cancer enriched" "Detected in many" 4 "glioma: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.7;HDLM-2: 11.0;HUVEC TERT2: 16.9;SH-SY5Y: 5.6;TIME: 25.8;U-2 OS: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: AB_10962628" "unprognostic (9.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (3.04e-3)" "unprognostic (1.46e-1)" "unprognostic (6.21e-2)" "unprognostic (2.36e-1)" "unprognostic (3.02e-3)" "unprognostic (6.42e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (5.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-1)" "unprognostic (8.31e-2)" 6.7 1.9 12.4 0.7 15.1 0.0 5.7 0.5 16.7 3.2 0.0 1.8 0.6 3.4 0.6 1.4 2.9 1.4 6.7 16.0 5.8 4.7 1.0 9.3 0.5 4.6 3.0 1.2 1.1 1.0 6.2 3.9 3.6 2.3 0.5 5.6 1.1 0.8 2.3 1.1 1.7 2.0 0.6 1.5 1.5 2.0 4.6 0.4 4.5 2.5 0.2 2.5 2.0 9.8 0.0 0.1 9.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 1.3 0.0 0.0 11.0 0.4 0.0 0.1 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 5.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 15.1 0.5 16.7 16.0 5.8 4.6 3.0 3.6 0.6 4.6 9.8 39.4 0.0 0.0 5.9 0.1 0.6 0.2 0.0 0.6 56.7 0.1 0.5 3.4 1.5 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.1 32.0 0.0 0.0 21.8 0.2 0.0 1.2 0.0 0.1 0.0 0.1 42.5 0.5 0.1 21.9 20.9 0.0 0.0 1.6 1.5 3.5 0.0 0.1 0.0 9.4 0.0 1.3 0.0 11.6 9.5 0.2 0.0 0.4 1.2 0.3 0.0 0.0 0.0 3.3 0.0 0.6 0.6 2.4 2.3 0.3 0.1 0.0 0.5 0.4 0.0 0.3 NOX4 "KOX, KOX-1" ENSG00000086991 "NADPH oxidase 4" Q9NPH5 11 89324353-89498187 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 138.0" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 164.0" "Cancer enhanced" "Detected in many" "renal cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 14.3;HUVEC TERT2: 27.7;TIME: 70.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.91e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-3)" "unprognostic (6.58e-3)" "unprognostic (1.92e-1)" "unprognostic (2.33e-1)" "unprognostic (8.83e-3)" "unprognostic (8.95e-3)" "unprognostic (3.80e-1)" "unprognostic (6.88e-2)" "unprognostic (1.56e-2)" "unprognostic (1.73e-1)" "prognostic favorable (6.14e-4)" "unprognostic (1.99e-4)" "unprognostic (9.71e-2)" "unprognostic (5.69e-2)" "unprognostic (3.03e-3)" 7.8 0.7 0.7 0.7 1.2 0.2 3.8 0.7 1.2 1.5 0.0 1.2 0.2 4.9 0.4 0.4 1.3 2.4 7.6 0.4 0.6 138.0 0.3 1.5 0.2 1.0 0.7 0.8 0.3 3.6 0.9 3.1 0.9 1.0 0.3 17.1 3.0 1.3 1.7 1.4 0.6 3.4 0.8 0.4 0.5 0.3 0.7 0.1 2.1 3.5 0.5 1.4 1.1 1.7 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.5 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.1 14.3 27.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 6.1 0.0 0.0 0.3 7.1 0.4 0.0 70.6 0.2 5.0 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 1.2 0.7 1.2 0.4 0.6 1.0 0.7 0.9 0.8 0.7 1.7 4.4 0.0 0.0 2.9 1.0 0.6 0.1 0.4 0.0 7.5 0.2 0.3 1.0 0.0 0.0 11.0 6.2 2.2 0.2 0.1 15.6 0.0 0.8 1.0 1.4 5.9 0.0 0.0 30.0 0.0 0.8 9.2 0.0 3.0 0.0 0.6 2.5 0.1 0.2 0.0 21.1 0.0 0.0 0.0 0.5 0.7 0.3 1.3 0.0 6.5 0.1 4.5 0.0 7.1 28.4 0.1 0.0 1.2 0.3 0.1 0.0 164.0 0.0 27.1 0.0 1.2 1.0 0.6 0.7 0.1 0.3 2.5 1.1 0.1 0.0 0.1 NR2F2 "ARP1, COUP-TFII, COUPTF2, COUPTFB, NF-E3, SVP40, TFCOUP2" ENSG00000185551 "Nuclear receptor subfamily 2 group F member 2" P24468 15 96325938-96340263 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 292.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 542.2;Hepatic stellate cells: 395.5;Leydig cells: 510.4;Peritubular cells: 610.5;Sertoli cells: 486.4;Smooth muscle cells: 385.7;Theca cells: 572.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058974 Approved Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA058974: AB_2732629" "unprognostic (9.28e-2)" "unprognostic (2.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.42e-2)" "unprognostic (8.96e-2)" "unprognostic (5.44e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (2.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.89e-1)" "unprognostic (9.19e-2)" "unprognostic (5.14e-2)" "unprognostic (5.96e-2)" "unprognostic (1.72e-2)" "unprognostic (7.47e-2)" "unprognostic (1.28e-2)" 95.5 43.1 32.7 18.8 19.2 0.1 59.7 15.0 19.6 128.6 23.5 52.6 21.5 120.9 61.8 22.1 101.5 65.7 44.4 20.0 24.8 79.8 32.1 56.8 42.4 16.2 21.9 292.4 20.0 30.7 20.3 74.7 18.2 60.6 26.7 2.5 22.9 126.4 33.1 24.1 32.1 81.8 12.5 106.2 82.3 26.7 49.3 7.8 46.2 31.5 15.1 46.3 74.5 10.7 154.7 39.1 125.6 78.5 249.1 85.5 41.9 109.1 83.2 111.1 94.3 134.8 153.4 0.1 86.8 55.2 44.1 90.4 22.3 78.3 138.8 0.5 86.5 49.9 48.7 24.6 69.5 38.7 18.0 61.3 26.5 92.5 19.8 130.5 207.3 0.1 135.3 0.4 71.2 105.5 0.1 27.6 1.2 59.6 52.7 0.1 30.9 0.2 244.7 165.7 15.8 0.2 12.3 3.7 17.5 55.0 61.1 2.8 215.3 119.9 39.7 28.3 38.8 0.1 0.4 0.4 67.0 18.9 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 19.2 15.0 19.6 20.0 24.8 16.2 21.9 18.2 12.5 49.3 10.7 133.4 28.9 18.1 0.7 1.1 14.4 24.9 71.7 39.3 7.5 51.9 50.8 46.4 203.0 34.6 62.5 25.0 126.2 2.0 35.7 46.9 22.0 3.2 70.9 542.2 166.1 26.4 5.3 0.1 10.9 50.3 125.8 80.0 68.9 0.0 41.5 395.5 51.6 10.3 3.3 24.8 35.5 32.6 12.2 20.1 22.9 510.4 5.0 26.6 36.5 0.6 30.2 0.0 0.0 0.5 15.6 23.9 610.5 2.8 22.3 14.3 65.5 37.3 13.8 486.4 27.8 385.7 6.4 7.9 20.5 10.4 35.3 5.8 572.5 27.1 21.3 NR3C2 "MLR, MR" ENSG00000151623 "Nuclear receptor subfamily 3 group C member 2" P08235 4 148078762-148444698 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 265.8;Excitatory neurons: 275.7;Inhibitory neurons: 269.9;Microglial cells: 176.1;Oligodendrocyte precursor cells: 230.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.8" "Lineage enriched" "Detected in single" 6 "T-cells: 1.8" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 9.7;HUVEC TERT2: 6.0;Karpas-707: 6.9;PC-3: 6.1;RPTEC TERT1: 7.8;TIME: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009155, HPA074979" Enhanced Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB009155: AB_2155949, HPA074979: AB_2686724" "unprognostic (2.75e-3)" "unprognostic (2.63e-2)" "unprognostic (6.70e-3)" "unprognostic (1.52e-1)" "unprognostic (4.09e-1)" "unprognostic (7.82e-3)" "unprognostic (1.04e-2)" "unprognostic (1.11e-2)" "unprognostic (1.14e-1)" "unprognostic (4.35e-2)" "unprognostic (4.97e-2)" "unprognostic (2.39e-1)" "prognostic favorable (3.10e-11)" "unprognostic (1.42e-1)" "unprognostic (1.87e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" 4.6 4.5 4.5 3.7 5.6 1.0 4.8 9.2 11.7 5.6 4.0 21.8 8.7 6.2 3.8 3.1 5.9 5.8 9.4 13.7 3.5 12.1 8.5 7.3 3.1 3.0 5.9 14.7 7.6 12.5 5.5 1.8 3.0 3.7 26.2 8.5 10.7 4.3 12.1 3.0 15.3 4.9 3.2 5.2 8.3 4.3 6.1 2.9 19.7 14.1 2.1 5.9 3.3 4.8 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.4 0.0 0.0 1.4 2.6 1.0 0.2 0.0 1.3 0.7 0.1 0.2 2.3 0.2 0.6 0.0 0.0 1.7 0.3 0.1 0.0 0.0 0.0 9.7 6.0 0.9 0.0 6.9 2.0 0.0 0.0 0.0 0.1 1.2 6.1 0.5 0.0 0.1 7.8 0.1 0.1 0.0 0.0 1.4 0.6 0.1 0.7 0.0 8.7 4.3 2.5 0.1 0.8 0.0 0.0 0.1 1.4 0.6 1.0 0.0 0.0 0.0 0.5 0.0 1.8 0.1 0.7 0.4 0.0 0.2 1.0 1.1 0.0 0.0 0.2 0.0 0.2 0.1 4.5 5.6 9.2 11.7 13.7 3.5 3.0 5.9 3.0 3.2 6.1 4.8 11.9 28.9 13.9 265.8 5.1 2.0 2.2 0.4 6.2 10.3 6.2 5.8 20.3 7.2 6.7 11.0 18.8 0.9 1.0 76.1 9.8 3.0 68.2 2.1 1.1 8.2 18.0 0.0 275.7 5.8 0.5 5.9 13.7 2.6 5.7 6.4 8.6 7.0 0.6 13.5 269.9 44.6 6.1 2.9 2.4 41.8 4.4 1.7 7.2 176.1 1.2 8.1 1.0 230.2 95.7 3.2 26.8 3.8 0.8 1.8 26.4 2.3 4.7 9.6 0.0 14.7 5.1 1.8 5.6 2.6 1.7 0.1 4.9 1.8 21.5 2.1 NUMB C14orf41 ENSG00000133961 "NUMB endocytic adaptor protein" P49757 14 73275107-73458617 "Cancer-related genes, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 290.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002874, CAB011478" Approved Enhanced "Cell Junctions" NA NA 12000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "CAB011478: AB_443023, HPA002874: " "unprognostic (5.28e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-1)" "unprognostic (1.32e-3)" "unprognostic (2.02e-1)" "unprognostic (2.01e-1)" "unprognostic (2.43e-1)" "unprognostic (9.49e-2)" "unprognostic (1.33e-2)" "unprognostic (4.08e-3)" "unprognostic (2.65e-3)" "unprognostic (4.14e-2)" "prognostic favorable (2.32e-6)" "unprognostic (9.12e-2)" "unprognostic (1.63e-1)" "unprognostic (3.92e-2)" "unprognostic (2.87e-1)" 35.6 25.9 17.3 37.7 19.2 35.5 33.0 20.4 23.4 34.3 22.0 46.3 46.6 35.6 25.9 40.0 39.0 41.7 28.8 20.9 17.6 41.3 52.1 52.8 24.7 20.3 19.5 33.9 37.3 40.5 20.2 44.4 19.7 29.5 42.2 20.4 36.8 31.6 21.1 32.6 47.4 37.6 18.1 40.4 36.8 20.3 19.4 27.6 39.0 24.1 30.9 40.5 34.0 18.2 70.2 46.9 33.3 30.2 65.8 99.6 45.3 64.9 87.2 51.2 54.1 57.0 86.0 31.9 39.7 80.7 37.8 45.2 39.8 66.6 77.2 48.9 22.2 25.5 28.2 37.3 69.7 23.7 57.5 56.0 70.3 126.2 74.8 56.2 112.3 49.2 47.0 37.1 65.6 62.9 43.3 32.8 15.4 78.9 50.1 27.6 46.7 21.6 71.2 105.3 13.6 35.3 81.0 54.2 33.4 55.9 81.3 34.5 108.8 76.2 42.7 49.3 28.2 30.9 38.9 29.2 153.1 27.4 34.3 91.9 93.3 96.8 12.6 76.4 13.2 22.6 12.7 14.0 68.7 21.4 12.9 11.8 290.3 12.8 102.8 12.8 17.9 64.5 17.3 19.2 20.4 23.4 20.9 17.6 20.3 19.5 19.7 18.1 19.4 18.2 54.4 64.1 49.0 108.4 53.6 42.8 27.7 38.6 42.1 30.7 38.4 26.0 22.0 44.3 50.0 55.2 81.3 26.0 29.9 59.3 25.4 27.9 11.9 68.2 35.0 59.2 40.7 22.9 151.1 26.4 31.0 37.5 43.8 56.6 24.1 26.3 52.1 51.0 42.6 15.2 78.8 39.4 36.7 91.5 109.7 8.1 45.1 94.1 46.2 141.5 117.3 42.6 39.1 62.4 81.8 46.9 39.3 36.9 40.9 37.1 64.7 43.2 56.9 46.4 26.3 22.8 29.7 59.2 32.7 35.6 46.5 34.3 25.6 16.7 37.5 44.6 NYNRIN "CGIN1, FLJ11811, KIAA1305" ENSG00000205978 "NYN domain and retroviral integrase containing" Q9P2P1 14 24399003-24419283 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 18.2;Squamous epithelial cells: 18.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 14.4;HEL: 14.7;HUVEC TERT2: 35.6;RT4: 29.8;TIME: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018945 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA018945: AB_1859538" "unprognostic (9.41e-3)" "unprognostic (3.96e-2)" "unprognostic (2.02e-1)" "unprognostic (4.49e-3)" "unprognostic (5.08e-2)" "unprognostic (1.14e-2)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (1.44e-3)" "unprognostic (4.21e-1)" "unprognostic (1.01e-1)" "unprognostic (4.51e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-2)" "unprognostic (1.86e-1)" "unprognostic (3.39e-1)" "unprognostic (2.43e-1)" 8.7 3.7 4.3 3.1 3.9 0.4 6.3 16.3 4.6 16.8 5.4 7.6 4.0 11.5 28.0 11.6 16.9 8.6 7.5 3.2 6.6 6.3 4.5 8.1 1.9 5.8 5.4 35.1 3.8 5.8 5.8 12.8 6.3 7.5 5.5 1.8 7.4 14.9 3.8 13.3 5.3 10.5 3.2 4.4 6.0 5.1 7.8 4.5 7.8 4.2 2.9 9.5 14.0 2.8 0.2 0.1 4.6 0.0 6.3 13.0 0.3 2.2 2.3 1.5 1.6 3.3 14.4 0.4 0.6 8.6 0.2 0.0 7.5 0.2 1.5 0.0 0.8 14.7 2.0 0.3 4.7 0.0 0.0 13.3 0.6 1.0 0.0 2.6 35.6 0.1 2.4 0.0 0.2 0.6 0.0 0.8 2.7 1.0 0.0 1.9 0.0 0.0 0.0 29.8 0.6 10.0 0.0 1.3 0.2 11.2 2.5 2.1 17.4 0.1 8.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.3 3.9 16.3 4.6 3.2 6.6 5.8 5.4 6.3 3.2 7.8 2.8 15.2 3.2 1.7 4.9 0.1 4.6 3.9 9.5 15.4 0.5 1.8 3.6 3.1 8.6 15.6 9.2 0.0 1.1 1.6 2.7 0.0 4.1 0.8 1.4 10.8 15.0 5.4 3.6 1.0 3.0 1.0 10.1 10.7 1.7 0.0 12.0 18.2 2.7 10.7 0.0 3.9 9.0 4.1 9.0 1.4 0.2 2.5 1.4 3.6 3.7 0.7 5.4 0.0 0.5 0.1 4.8 5.1 0.4 1.2 1.2 1.0 0.3 10.8 0.2 0.0 1.2 7.3 0.3 1.2 18.0 3.8 1.1 0.3 1.5 8.8 4.5 OSTC DC2 ENSG00000198856 "Oligosaccharyltransferase complex non-catalytic subunit" Q9NRP0 4 108650585-108667820 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 628.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.26e-1)" "unprognostic (1.00e-1)" "unprognostic (2.10e-2)" "prognostic favorable (1.44e-4)" "unprognostic (6.05e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (6.46e-2)" "unprognostic (4.55e-2)" "unprognostic (3.13e-3)" "unprognostic (9.16e-3)" "prognostic unfavorable (2.31e-8)" "unprognostic (2.06e-1)" "unprognostic (1.68e-1)" "unprognostic (4.06e-2)" "unprognostic (1.55e-2)" 72.6 74.1 22.8 84.2 23.7 98.9 99.8 24.1 29.8 118.6 35.0 85.1 96.2 87.1 180.0 77.5 72.7 82.4 51.6 22.3 26.5 74.6 193.9 64.6 87.8 25.9 24.1 69.7 132.9 51.1 82.8 105.4 24.7 64.6 98.4 22.6 83.5 59.6 24.3 47.8 89.1 82.7 25.1 70.1 87.1 39.2 26.4 91.6 106.2 30.6 80.9 92.5 60.4 26.8 123.2 75.5 200.2 138.2 419.3 556.1 158.0 328.3 316.8 166.9 203.0 161.6 274.7 258.5 236.0 388.7 101.2 81.6 159.8 133.5 192.8 108.8 117.4 133.0 99.7 357.0 336.8 304.0 124.1 362.8 253.7 137.4 280.2 349.9 379.6 160.1 255.0 295.1 329.5 152.2 213.1 264.7 137.2 332.2 95.7 216.2 217.5 284.6 292.1 85.9 99.9 123.4 111.8 265.0 262.9 245.2 122.4 246.5 298.5 175.4 185.3 132.2 135.9 168.0 183.1 254.0 225.1 183.9 195.7 146.4 136.2 76.4 130.4 145.5 202.4 120.2 138.0 143.0 204.0 91.5 128.3 139.2 18.6 152.7 125.9 375.9 105.5 227.2 22.8 23.7 24.1 29.8 22.3 26.5 25.9 24.1 24.7 25.1 26.4 26.8 123.1 38.5 48.5 11.8 128.4 97.3 114.1 413.8 86.6 15.1 178.3 197.1 34.2 124.4 235.4 84.6 16.7 276.9 199.9 54.6 88.0 221.7 9.4 105.4 337.0 120.0 58.0 105.5 9.4 159.5 628.6 200.2 120.8 180.5 122.4 169.5 111.4 187.1 256.1 11.8 13.3 274.2 209.5 139.9 196.7 10.1 164.1 138.5 161.9 6.5 140.0 50.2 140.1 12.1 17.5 160.3 90.4 109.1 424.4 183.7 166.5 173.9 126.9 17.3 72.3 108.8 175.3 74.5 72.4 134.9 117.9 365.4 117.2 197.4 178.5 145.2 P4HA3 C-P4Halpha(III) ENSG00000149380 "Prolyl 4-hydroxylase subunit alpha 3" Q7Z4N8 11 74235801-74311640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 10.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Early spermatids: 25.6;Erythroid cells: 13.5;Horizontal cells: 18.5;Rod photoreceptor cells: 12.8;Spermatocytes: 13.1;Spermatogonia: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 19.5;fHDF/TERT166: 9.5;HSkMC: 9.1;HUVEC TERT2: 38.2;TIME: 27.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA007897 Approved "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA007897: AB_2156427" "unprognostic (2.74e-2)" "unprognostic (1.37e-4)" "unprognostic (1.31e-3)" "unprognostic (3.19e-2)" "unprognostic (2.54e-4)" "unprognostic (9.65e-3)" "unprognostic (4.34e-2)" "unprognostic (3.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.21e-3)" "unprognostic (1.38e-2)" "unprognostic (8.31e-2)" "prognostic unfavorable (3.34e-9)" "unprognostic (1.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (7.83e-4)" 1.6 0.7 0.1 3.9 0.0 0.0 0.9 0.1 0.3 1.3 0.3 1.6 0.3 4.5 0.5 0.3 1.2 5.6 0.3 0.0 0.1 1.0 1.3 1.4 0.9 0.1 0.1 1.0 0.2 0.0 3.7 3.9 0.1 6.3 0.7 0.0 0.5 4.3 0.1 0.3 0.4 10.5 0.0 0.1 0.4 1.5 0.1 0.1 2.6 0.1 0.3 5.4 1.7 0.1 0.0 1.4 1.7 0.0 6.2 0.7 0.0 19.5 1.4 1.0 2.1 0.0 0.0 0.0 1.8 9.5 0.7 0.0 0.0 0.3 0.2 0.0 0.1 0.0 1.2 0.0 8.0 0.0 0.0 9.1 0.0 6.5 0.7 1.1 38.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 27.4 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.2 0.4 0.7 0.9 0.0 9.1 0.5 0.1 0.4 0.0 0.2 0.0 14.6 0.2 3.1 0.2 0.0 0.2 25.6 3.8 2.5 3.2 0.0 13.5 2.4 0.0 0.4 5.2 0.0 1.0 0.0 4.3 6.1 0.0 0.4 18.5 3.3 0.2 0.0 0.9 1.1 3.2 0.0 0.3 0.0 6.5 1.6 1.9 3.1 1.5 0.9 0.8 0.2 0.4 0.0 1.1 0.2 0.0 0.7 12.8 0.0 2.1 5.4 13.1 12.2 0.1 0.3 0.1 0.4 1.3 0.2 0.6 PALMD "C1orf11, FLJ20271, PALML" ENSG00000099260 Palmdelphin Q9NP74 1 99646113-99694541 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 130.8" "Cell type enhanced" "Detected in many" "Adipocytes: 537.2;Cardiomyocytes: 157.6;Endothelial cells: 219.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 155.2;LHCN-M2: 49.5;TIME: 220.5;U-87 MG: 92.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017959, HPA030549" Supported Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Focal adhesion sites" "HPA017959: AB_1854949, HPA030549: AB_2673518" "unprognostic (1.48e-2)" "unprognostic (1.15e-2)" "unprognostic (2.05e-2)" "prognostic favorable (9.42e-4)" "unprognostic (7.67e-2)" "prognostic favorable (5.90e-5)" "unprognostic (1.54e-2)" "unprognostic (2.10e-1)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (8.32e-2)" "unprognostic (6.18e-2)" "unprognostic (5.19e-2)" "unprognostic (1.63e-2)" "unprognostic (1.88e-1)" "unprognostic (2.70e-1)" "unprognostic (8.08e-2)" 130.8 43.0 14.6 7.1 11.7 0.0 77.6 10.5 15.3 27.4 45.8 9.5 3.4 33.0 6.1 38.2 22.8 14.6 91.2 13.7 12.7 11.0 57.1 28.4 3.9 12.0 11.8 18.8 4.9 9.2 10.5 43.2 11.5 18.0 6.5 7.5 71.0 7.9 112.6 48.9 8.6 31.4 11.1 6.3 6.1 11.0 14.1 8.0 7.2 66.2 8.6 14.5 15.9 10.4 0.0 0.3 0.4 0.2 7.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 39.2 2.5 0.6 10.8 0.0 0.5 0.1 0.1 0.1 0.0 18.6 26.4 0.0 0.0 0.1 3.9 2.0 0.0 0.0 4.3 155.2 0.0 22.7 0.0 49.5 0.6 0.0 0.0 0.0 1.6 6.8 0.0 38.2 0.1 0.0 8.0 0.9 0.5 0.0 9.9 0.0 1.0 2.3 0.0 220.5 0.0 0.4 16.8 0.0 0.0 0.0 0.1 92.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 11.7 10.5 15.3 13.7 12.7 12.0 11.8 11.5 11.1 14.1 10.4 537.2 6.4 5.6 0.3 0.5 38.5 11.4 49.6 22.2 2.0 20.0 31.8 157.6 32.9 35.9 3.7 0.0 0.4 1.6 0.1 5.9 8.1 74.9 78.7 71.9 219.4 1.8 2.7 1.4 0.2 0.3 19.2 2.0 17.7 1.3 0.0 96.0 57.3 0.6 3.3 1.8 0.0 14.2 2.2 5.5 12.2 9.3 1.7 24.9 73.1 0.0 55.0 0.0 0.5 0.2 4.1 0.0 24.0 0.0 5.9 0.0 0.4 111.5 3.3 0.0 91.3 12.7 0.5 0.6 27.5 46.5 0.3 1.4 110.1 0.1 3.3 PCDH1 pc42 ENSG00000156453 "Protocadherin 1" Q08174 5 141853090-141879246 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 61.5;Distal enterocytes: 66.4;Exocrine glandular cells: 46.3;Pancreatic endocrine cells: 65.2;Urothelial cells: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 86.1;HaCaT: 108.0;HUVEC TERT2: 56.2;OE19: 77.8;RT4: 74.2;TIME: 74.5;WM-115: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047720, HPA050538" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA 2500000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cell Junctions" Nucleoli "HPA047720: AB_2680130, HPA050538: AB_2681162" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (5.30e-2)" "unprognostic (4.61e-3)" "unprognostic (5.03e-2)" "unprognostic (4.16e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (1.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.43e-1)" "prognostic favorable (7.55e-5)" "unprognostic (2.05e-1)" "unprognostic (4.16e-2)" "unprognostic (3.13e-2)" "unprognostic (1.91e-1)" 24.0 4.0 11.7 7.7 15.9 1.2 22.8 3.3 15.1 11.6 0.0 23.1 21.4 9.2 6.4 41.7 9.1 6.6 19.3 17.0 2.3 21.3 19.3 27.7 2.0 0.0 0.8 2.5 13.8 3.8 6.5 19.2 0.0 10.8 14.3 3.4 28.8 11.2 8.2 27.4 17.1 7.2 1.1 1.8 23.6 1.1 2.7 1.0 12.6 11.1 9.1 9.8 19.2 5.7 18.9 1.0 7.7 8.5 0.3 0.0 5.5 0.2 0.2 0.1 0.0 4.5 86.1 0.1 43.7 0.6 1.0 108.0 9.9 7.9 0.0 0.1 0.3 0.0 0.4 0.1 6.9 0.0 0.3 0.0 17.8 0.1 1.2 18.1 56.2 0.0 0.1 9.2 0.0 15.1 0.3 0.0 32.5 77.8 14.6 0.3 0.1 13.2 6.3 74.2 0.9 1.8 0.5 23.3 20.0 21.6 18.8 0.4 74.5 0.1 0.7 0.1 6.9 0.0 0.1 0.2 0.5 0.0 52.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 11.7 15.9 3.3 15.1 17.0 2.3 0.0 0.8 0.0 1.1 2.7 5.7 61.5 0.0 5.3 3.6 0.2 1.0 12.0 4.6 0.0 9.6 9.5 4.7 4.4 20.0 8.6 12.9 0.0 0.7 2.0 66.4 3.9 15.3 1.3 10.1 2.1 34.2 7.7 2.7 12.3 46.3 0.3 2.6 21.9 21.3 0.0 0.0 7.5 30.1 0.2 26.9 6.1 21.3 12.2 1.4 2.3 2.5 0.6 0.5 0.0 6.5 0.0 4.8 7.2 5.5 7.2 65.2 30.3 0.4 1.4 25.8 36.4 5.2 7.1 0.5 13.1 0.9 18.5 0.3 0.2 7.4 2.6 20.1 0.9 0.5 18.9 54.5 PCDH10 "KIAA1400, OL-PCDH" ENSG00000138650 "Protocadherin 10" Q9P2E7 4 133149294-133208606 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 35.4;placenta: 25.9;prostate: 10.6;seminal vesicle: 17.3" "Cell type enhanced" "Detected in many" "Astrocytes: 58.1;Endometrial ciliated cells: 26.5;Excitatory neurons: 64.9;Glandular and luminal cells: 29.1;Inhibitory neurons: 57.7;Oligodendrocyte precursor cells: 46.8;Oligodendrocytes: 59.6" "Cancer enhanced" "Detected in many" "glioma: 8.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 11.5;HUVEC TERT2: 27.4;MOLT-4: 24.1;TIME: 55.4;U-138 MG: 14.5;U-251 MG: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011220, HPA073462" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA 88000 "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA011220: AB_1855041, HPA073462: AB_2686605" "unprognostic (7.20e-2)" "unprognostic (8.74e-3)" "unprognostic (4.30e-2)" "unprognostic (8.12e-5)" "unprognostic (8.33e-2)" "unprognostic (3.20e-1)" "unprognostic (5.27e-3)" "unprognostic (4.51e-1)" "unprognostic (3.83e-2)" "unprognostic (1.15e-1)" "unprognostic (9.30e-3)" "unprognostic (8.72e-2)" "unprognostic (1.45e-1)" "unprognostic (8.68e-4)" "unprognostic (8.88e-2)" "unprognostic (6.31e-2)" "unprognostic (2.16e-4)" 0.5 5.1 20.5 0.2 35.4 0.0 0.1 0.9 23.9 1.5 0.0 0.5 0.1 1.6 0.5 0.3 1.2 0.5 1.2 19.6 15.2 2.1 0.1 0.7 0.0 7.7 24.9 2.3 0.2 0.0 1.4 25.9 11.3 10.6 0.2 3.0 0.5 17.3 0.0 0.0 0.4 0.7 3.7 0.0 0.4 1.4 16.8 0.1 0.5 0.0 0.0 1.8 2.8 19.1 0.0 0.7 8.7 0.0 0.3 0.0 0.0 8.6 4.6 0.7 0.4 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.9 0.0 4.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 11.5 27.4 0.0 0.3 0.0 4.2 0.0 24.1 0.0 0.0 0.0 0.3 0.5 0.3 0.5 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.3 55.4 14.5 0.0 0.1 12.9 0.0 0.0 0.0 1.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 35.4 0.9 23.9 19.6 15.2 7.7 24.9 11.3 3.7 16.8 19.1 1.4 0.0 0.6 58.1 0.0 0.1 0.5 0.1 1.2 15.0 1.2 2.7 2.3 0.0 0.7 0.0 0.0 0.8 0.0 0.9 1.9 0.0 5.6 26.5 4.6 4.0 0.0 0.0 64.9 0.0 0.9 15.5 0.0 29.1 0.0 5.0 0.0 0.0 1.8 0.0 57.7 0.2 0.0 0.0 0.0 1.7 0.0 0.5 0.0 6.5 0.0 8.6 0.0 46.8 59.6 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.1 2.7 0.0 4.3 11.5 17.4 0.9 0.0 0.3 2.9 0.2 3.9 0.1 0.4 PDCD6IP "AIP1, Alix, Hp95" ENSG00000170248 "Programmed cell death 6 interacting protein" Q8WUM4 3 33798571-33869707 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 299.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA011905, CAB016212, HPA051604" Approved Approved Vesicles,Centrosome "Intracellular and membrane" NA NA 4100000 "Cluster 27: Non-specific - Gene expression" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Centrosome "CAB016212: AB_673819, HPA011905: AB_1855111, HPA051604: " "unprognostic (1.53e-1)" "unprognostic (2.63e-1)" "prognostic favorable (1.16e-4)" "unprognostic (2.17e-1)" "unprognostic (2.75e-1)" "unprognostic (5.12e-2)" "unprognostic (7.76e-3)" "unprognostic (1.23e-2)" "unprognostic (3.29e-1)" "unprognostic (2.86e-1)" "unprognostic (3.88e-3)" "unprognostic (4.49e-2)" "prognostic favorable (3.90e-9)" "unprognostic (9.61e-2)" "unprognostic (1.89e-1)" "unprognostic (4.78e-1)" "unprognostic (1.11e-1)" 33.1 27.6 16.3 24.5 17.9 21.2 32.9 18.4 23.3 35.0 23.0 46.4 36.2 35.1 26.4 46.0 30.9 25.9 30.5 17.6 19.7 35.0 33.2 35.2 26.1 25.2 18.1 34.3 25.0 40.6 22.8 31.2 26.4 30.0 41.5 30.5 29.7 23.7 33.9 39.8 38.8 31.8 18.6 27.5 37.2 23.8 18.8 24.4 34.2 22.1 30.1 26.9 35.9 21.4 47.2 46.4 30.2 25.1 78.5 80.6 34.3 67.2 56.2 50.9 52.2 33.3 43.8 75.9 33.8 77.7 32.2 45.5 47.8 61.4 57.8 27.4 39.5 56.7 37.4 28.2 50.8 56.5 57.6 62.2 69.5 57.6 67.8 60.5 77.1 32.4 50.3 26.2 74.4 27.0 36.3 31.8 29.9 43.5 57.8 32.8 36.5 43.8 64.6 39.2 14.7 26.8 61.6 67.8 30.7 48.9 62.0 51.4 101.1 59.5 28.2 50.1 46.9 26.6 37.6 55.6 56.7 62.6 28.8 6.8 13.5 11.0 8.0 18.1 8.7 12.0 8.9 8.1 12.4 10.8 7.7 7.5 6.8 12.1 18.0 5.0 9.4 10.0 16.3 17.9 18.4 23.3 17.6 19.7 25.2 18.1 26.4 18.6 18.8 21.4 78.5 86.6 84.8 85.8 76.1 41.7 62.6 62.7 51.8 28.6 42.5 34.0 53.4 62.9 80.6 64.4 52.1 53.0 58.5 299.9 37.2 67.2 85.3 121.6 84.0 68.8 36.1 40.6 83.5 78.3 52.8 54.3 96.8 77.8 53.7 53.0 54.3 57.3 60.6 25.2 69.2 97.1 63.1 93.0 44.7 50.4 74.0 85.0 28.4 75.9 71.0 23.1 42.2 96.0 161.7 122.5 127.1 80.5 46.9 56.5 130.2 61.0 130.9 49.9 46.0 42.3 50.4 93.0 48.4 61.5 43.2 96.6 55.2 47.7 86.7 70.3 PDCL "DKFZp564M1863, PhLP" ENSG00000136940 "Phosducin like" Q13371 9 122798389-122828588 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021571, HPA021647, CAB026473" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol Nucleoplasm "CAB026473: , HPA021571: AB_1855114, HPA021647: AB_1855115" "unprognostic (3.51e-2)" "unprognostic (4.11e-2)" "unprognostic (2.78e-1)" "unprognostic (1.17e-2)" "unprognostic (1.39e-2)" "unprognostic (1.39e-1)" "unprognostic (8.74e-3)" "unprognostic (1.77e-1)" "unprognostic (3.13e-2)" "unprognostic (1.49e-2)" "unprognostic (1.52e-1)" "unprognostic (1.50e-1)" "prognostic favorable (7.00e-4)" "unprognostic (9.84e-2)" "unprognostic (1.35e-1)" "unprognostic (3.35e-1)" "unprognostic (2.93e-1)" 11.0 8.7 6.8 10.4 9.5 19.4 13.0 8.5 8.7 12.1 7.3 10.2 9.3 13.4 7.7 9.8 10.3 9.5 8.8 6.5 9.2 8.8 6.4 13.1 13.1 8.8 8.4 9.9 6.8 11.0 5.0 14.1 9.2 11.1 10.5 12.4 12.8 9.2 5.9 10.6 9.1 11.3 7.4 12.7 10.7 6.7 8.5 13.1 11.6 6.9 12.3 9.2 7.5 10.6 16.9 23.2 38.4 14.4 34.1 22.5 21.4 23.1 23.8 20.9 21.2 15.2 21.9 28.1 18.7 27.5 23.0 32.3 24.1 22.6 22.7 28.0 12.1 29.2 30.1 25.3 17.4 24.6 55.3 19.7 15.8 20.7 10.3 19.3 43.3 17.6 29.7 16.1 23.1 25.8 27.1 22.2 28.4 28.8 17.6 27.8 36.5 20.9 25.6 0.0 30.8 27.4 31.3 17.3 13.8 25.1 26.5 16.8 48.4 19.4 23.0 28.4 22.8 12.0 26.7 30.5 16.6 19.6 19.0 30.4 13.8 23.9 15.2 12.5 16.2 12.7 18.2 14.1 14.5 16.0 18.5 16.4 11.4 19.8 21.8 17.0 31.3 13.4 6.8 9.5 8.5 8.7 6.5 9.2 8.8 8.4 9.2 7.4 8.5 10.6 43.0 9.6 9.2 5.2 16.7 24.2 14.7 25.4 25.6 42.6 19.9 16.0 5.7 14.3 13.4 20.2 22.9 27.6 29.1 12.9 9.8 20.7 5.5 29.9 22.3 37.5 12.6 50.5 5.8 18.0 27.3 26.7 9.7 36.3 57.1 14.4 31.8 7.6 24.9 40.4 8.2 19.0 24.4 22.6 15.7 4.1 23.0 19.3 19.6 10.3 30.4 36.1 20.6 6.6 15.4 16.5 13.2 17.0 18.2 15.8 9.1 15.3 21.9 38.2 19.7 15.8 21.6 14.5 21.9 25.8 23.2 31.9 25.9 19.9 13.5 16.5 PDE10A ENSG00000112541 "Phosphodiesterase 10A" Q9Y233 6 165327287-165988078 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 67.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 204.7;Inhibitory neurons: 209.6;Microglial cells: 89.0;Oligodendrocyte precursor cells: 48.7;Oligodendrocytes: 51.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "basal ganglia: 67.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 9.0;LHCN-M2: 12.5;RT4: 6.9;SH-SY5Y: 8.1;TIME: 11.3;U-2 OS: 7.0" "Region enriched" "Detected in all" 11 "basal ganglia: 350.1" "Region enriched" "Detected in all" 5 "basal ganglia: 194.1" "CAB045998, HPA047200" Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB045998: AB_2162589, HPA047200: AB_2679981" "unprognostic (1.02e-1)" "unprognostic (3.63e-2)" "unprognostic (3.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.20e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (9.36e-2)" "unprognostic (6.03e-2)" "unprognostic (3.79e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (4.44e-7)" "unprognostic (3.59e-3)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (5.90e-3)" 2.6 1.3 3.1 0.8 67.2 0.0 2.3 5.5 10.7 1.3 0.0 1.0 0.2 2.0 2.4 0.4 2.4 1.5 3.6 2.1 2.5 3.8 0.3 1.0 0.5 1.6 2.3 2.3 0.5 0.5 2.7 2.5 0.9 1.7 0.2 1.9 0.4 1.7 0.4 0.3 0.7 2.1 0.5 1.4 1.1 3.4 9.6 0.3 6.0 0.5 0.4 3.2 0.9 0.1 0.0 2.4 5.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.3 0.8 0.0 0.0 0.0 3.8 0.1 2.2 0.0 0.0 0.1 3.9 0.0 9.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.5 0.0 0.0 0.0 12.5 0.3 0.9 0.0 1.1 0.0 4.7 1.5 5.8 0.0 5.9 6.9 1.8 8.1 0.0 0.0 0.4 0.7 0.0 0.0 11.3 0.1 7.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 67.2 5.5 10.7 2.1 2.5 1.6 2.3 0.9 0.5 9.6 0.1 13.8 0.0 0.0 10.4 0.1 0.4 3.3 0.4 0.0 7.2 0.3 0.3 7.3 0.0 1.2 5.5 2.1 7.8 0.0 0.0 3.9 2.0 14.3 0.2 1.7 13.4 0.0 0.0 204.7 0.0 6.1 6.6 1.1 0.4 1.3 0.1 7.9 0.0 0.8 16.8 209.6 0.0 0.0 0.0 0.0 14.9 0.0 0.2 1.8 89.0 0.0 12.6 0.0 48.7 51.8 0.1 0.0 0.4 0.0 17.9 0.0 7.2 0.9 1.1 0.0 12.4 5.0 8.8 2.1 0.1 0.3 2.9 0.1 1.6 0.1 6.9 PDLIM4 RIL ENSG00000131435 "PDZ and LIM domain 4" P50479 5 132257696-132273454 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 315.5;Prostatic glandular cells: 473.0;Skeletal myocytes: 225.2;Urothelial cells: 381.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 91.8;HBEC3-KT: 109.2;HHSteC: 103.7;hTEC/SVTERT24-B: 117.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011912 Uncertain Approved "Actin filaments,Cytosol" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments, Cytosol" "HPA011912: AB_1856277" "unprognostic (1.36e-3)" "unprognostic (1.93e-1)" "unprognostic (1.62e-2)" "unprognostic (8.08e-3)" "unprognostic (4.70e-3)" "unprognostic (2.01e-2)" "unprognostic (1.89e-1)" "unprognostic (2.39e-1)" "unprognostic (1.34e-1)" "unprognostic (3.38e-2)" "unprognostic (3.94e-2)" "unprognostic (4.20e-2)" "unprognostic (5.84e-3)" "unprognostic (1.13e-2)" "unprognostic (2.61e-1)" "unprognostic (3.57e-2)" "unprognostic (3.40e-3)" 24.8 6.6 14.5 18.6 13.8 0.7 34.5 17.9 17.8 36.5 20.1 104.9 6.9 90.7 17.7 50.0 48.3 20.5 61.6 15.8 23.8 33.3 1.2 10.5 4.5 27.7 20.5 28.4 6.5 4.9 28.2 8.0 21.3 50.2 4.8 2.6 47.4 28.1 5.4 64.4 27.2 42.9 22.5 6.7 32.2 6.3 17.9 6.6 14.2 2.6 10.1 59.4 39.1 21.7 46.6 0.0 9.7 0.1 13.2 36.7 3.3 12.9 6.3 12.9 4.2 0.0 4.3 0.3 8.6 68.4 65.8 91.8 0.0 109.2 6.1 0.2 5.1 0.0 0.0 2.2 103.7 0.0 0.3 46.5 7.8 117.6 43.7 45.9 74.0 0.0 20.2 0.1 57.6 0.0 0.0 0.3 3.4 0.0 28.1 2.2 66.4 0.2 29.0 0.0 0.0 39.0 29.7 0.0 0.0 7.7 0.1 4.8 47.9 46.3 49.9 48.4 72.9 0.1 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 14.5 13.8 17.9 17.8 15.8 23.8 27.7 20.5 21.3 22.5 17.9 21.7 10.1 0.0 4.4 5.5 0.7 105.7 315.5 183.8 76.2 0.5 38.2 149.5 6.8 0.0 57.0 14.7 2.1 5.1 0.8 0.6 107.6 121.5 14.2 21.1 81.0 69.8 16.8 0.0 0.7 9.9 14.4 85.1 6.1 17.9 4.5 10.7 21.0 0.3 6.6 0.0 0.6 16.6 61.1 0.3 32.5 15.8 36.4 3.4 165.4 3.7 1.0 17.7 0.0 0.0 0.3 105.7 154.6 27.4 0.0 473.0 5.6 8.9 138.3 0.7 26.3 225.2 53.8 9.9 13.9 47.8 82.8 22.8 4.2 2.0 5.5 381.7 PDLIM5 "Enh, LIM" ENSG00000163110 "PDZ and LIM domain 5" Q96HC4 4 94451857-94668227 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 629.5;skeletal muscle: 1163.5;tongue: 576.0" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 1844.2" "Cancer enriched" "Detected in all" 8 "prostate cancer: 132.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 219.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 219.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013511, HPA016740, HPA020026" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 1200000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Focal adhesion sites" "CAB013511: AB_2533388, HPA016740: AB_1855153, HPA020026: AB_1855154" "unprognostic (6.20e-2)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.08e-2)" "unprognostic (6.61e-2)" "unprognostic (2.24e-1)" "unprognostic (1.33e-1)" "unprognostic (2.46e-2)" "unprognostic (7.60e-2)" "unprognostic (2.65e-1)" "unprognostic (1.18e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (2.11e-2)" "unprognostic (3.15e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" 41.7 26.0 20.5 25.6 25.2 59.7 39.5 22.4 22.4 27.4 84.9 34.1 33.3 94.8 11.3 72.3 40.5 47.5 629.5 21.4 27.7 34.9 82.7 22.0 16.2 30.9 30.1 27.2 30.2 12.2 17.5 67.7 25.0 88.5 30.8 18.2 40.2 68.9 1163.5 21.5 34.4 105.9 22.7 24.1 31.0 12.7 26.3 10.9 25.5 576.0 21.1 45.8 27.6 21.0 31.4 87.2 33.6 13.0 71.7 51.3 13.0 71.6 59.9 40.1 32.6 80.8 66.3 12.0 72.0 72.3 21.0 31.8 46.5 68.2 65.9 24.1 19.3 43.7 53.8 32.2 103.7 14.6 38.3 66.4 58.4 96.1 74.0 177.9 93.5 13.2 19.2 12.5 86.2 29.8 15.0 4.8 11.4 66.7 36.6 7.2 24.7 11.1 45.0 94.6 16.5 21.8 38.9 88.7 20.3 26.7 10.3 5.2 113.7 103.7 17.3 46.1 44.1 9.5 13.0 12.7 56.5 10.3 24.9 219.7 23.4 21.0 12.1 40.6 9.7 10.5 12.0 12.8 19.5 7.6 7.9 10.4 22.6 9.2 44.6 6.6 11.8 15.2 20.5 25.2 22.4 22.4 21.4 27.7 30.9 30.1 25.0 22.7 26.3 21.0 107.4 44.8 23.6 184.1 22.1 194.4 380.3 92.1 63.7 4.7 90.2 67.4 1844.2 62.9 82.9 49.7 31.3 13.7 18.5 180.0 13.7 95.0 19.2 68.7 11.8 117.2 109.4 27.6 4.9 95.1 96.5 97.8 84.6 108.7 52.0 29.1 137.8 207.0 38.8 1.7 20.7 107.4 36.7 60.6 75.3 9.1 41.3 59.8 62.2 104.0 41.6 86.2 12.3 181.5 43.1 139.2 166.8 66.5 23.2 300.7 117.5 73.6 70.0 35.8 78.9 96.7 134.7 23.8 34.4 107.3 157.0 23.8 31.1 6.8 74.0 217.5 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 80.0;Early spermatids: 144.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 14.2;basal ganglia: 20.1;cerebral cortex: 41.7;hippocampal formation: 23.4;white matter: 18.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 117.8;hTERT-RPE1: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavorable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favorable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 10.6 62.6 14.2 10.5 20.1 14.4 16.1 0.0 41.7 14.2 1.2 8.9 7.2 15.5 17.0 14.2 12.2 19.4 49.2 23.4 0.0 12.8 4.2 12.6 12.9 0.0 2.3 19.3 19.9 29.9 5.4 13.8 0.0 10.3 12.4 14.1 11.7 9.4 72.9 4.3 7.6 11.2 0.0 13.2 11.7 26.7 3.0 11.6 18.8 16.9 12.4 14.0 6.8 18.5 25.7 12.0 25.9 10.9 21.0 37.9 8.6 19.3 21.7 22.1 25.8 12.7 90.3 13.9 63.8 30.8 117.8 54.4 11.0 16.1 32.8 1.5 5.6 6.6 15.7 4.5 23.9 3.3 9.0 24.5 31.5 37.7 59.8 117.1 50.9 12.4 2.4 22.8 27.6 6.0 20.3 10.3 12.1 26.8 15.4 4.8 15.5 2.6 15.3 17.0 2.4 11.4 12.7 1.4 61.8 20.9 4.0 3.9 90.9 27.5 17.2 63.8 23.3 12.6 5.8 12.1 34.2 11.7 25.1 6.4 27.9 14.5 9.2 25.3 8.9 15.6 15.1 12.0 22.5 17.9 8.9 7.8 3.1 5.4 41.1 3.7 34.9 18.0 14.2 20.1 0.0 41.7 23.4 0.0 0.0 2.3 0.0 0.0 3.0 18.5 10.7 12.8 7.8 15.0 18.0 13.0 12.7 36.3 68.9 38.3 11.6 7.0 80.0 14.3 35.6 16.5 8.4 4.3 13.7 27.5 5.9 33.3 144.2 33.3 14.9 15.0 10.2 1.3 73.6 14.0 3.9 20.8 16.3 70.2 6.3 3.7 12.5 3.3 6.3 10.1 23.4 5.5 10.2 19.2 19.1 28.1 11.5 19.9 10.6 19.7 22.4 18.8 10.3 13.0 8.5 24.5 9.6 13.5 8.1 15.6 4.9 11.4 30.5 11.5 6.6 35.4 13.1 10.1 11.4 26.5 10.9 4.4 19.3 7.1 10.7 23.9 PEAR1 "FLJ00193, JEDI, MEGF12" ENSG00000187800 "Platelet endothelial aggregation receptor 1" Q5VY43 1 156893698-156916434 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.6;Endothelial cells: 30.6;Hepatic stellate cells: 40.0;Leydig cells: 44.4;Peritubular cells: 35.7;Sertoli cells: 26.3;Smooth muscle cells: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 19.5;HBEC3-KT: 29.9;HHSteC: 21.6;HUVEC TERT2: 52.2;TIME: 85.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035217 Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA 62000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cell Junctions" Centrosome "HPA035217: AB_10669902" "unprognostic (1.02e-1)" "unprognostic (1.84e-5)" "unprognostic (4.77e-2)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.48e-1)" "unprognostic (5.62e-2)" "unprognostic (5.93e-2)" "unprognostic (1.04e-2)" "unprognostic (3.99e-1)" "unprognostic (2.17e-1)" "unprognostic (5.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.20e-2)" "unprognostic (3.37e-3)" "unprognostic (8.51e-2)" "unprognostic (2.64e-2)" 19.0 5.0 2.5 2.3 3.0 2.3 12.9 1.2 4.1 12.3 2.0 4.5 1.6 10.0 1.1 2.6 9.1 7.4 8.7 1.2 1.7 4.8 2.1 11.8 3.8 2.0 2.3 9.1 2.3 1.7 3.4 11.7 2.3 4.7 0.9 0.4 2.9 3.7 5.7 4.2 4.1 4.6 1.1 7.0 3.7 3.0 2.9 1.4 9.7 7.6 1.1 6.0 7.3 1.4 0.5 2.9 0.8 0.0 0.0 3.7 0.1 11.7 19.5 4.8 2.8 0.3 0.5 0.0 0.6 8.7 0.4 0.2 0.0 29.9 1.3 0.2 0.0 14.8 0.7 0.8 21.6 0.1 0.0 11.3 0.1 6.5 1.5 1.0 52.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 6.9 0.0 0.0 85.2 0.1 6.4 2.6 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.5 3.0 1.2 4.1 1.2 1.7 2.0 2.3 2.3 1.1 2.9 1.4 44.6 0.0 3.2 0.0 0.4 0.9 0.1 0.7 1.2 2.4 0.6 1.3 7.5 1.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 1.2 0.2 2.5 30.6 1.8 5.7 0.0 0.4 0.1 10.1 1.5 0.4 1.3 0.1 40.0 0.4 0.5 0.0 0.0 2.3 0.0 1.6 1.5 3.5 44.4 3.0 5.4 12.2 0.4 0.2 0.0 0.0 0.0 1.2 0.0 35.7 0.0 0.2 0.0 0.1 0.2 0.2 26.3 1.7 34.2 1.5 1.5 0.2 1.1 0.3 0.3 1.1 0.3 0.2 PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Cell type enhanced" "Detected in many" "Adipocytes: 672.9;Endothelial cells: 468.2;Hepatic stellate cells: 275.3;Macrophages: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 773.0;TIME: 537.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" 195.6 21.4 20.3 78.9 21.4 35.5 128.5 21.9 25.3 54.9 21.7 37.9 29.7 51.1 9.2 54.3 45.1 88.6 70.3 18.0 22.2 43.6 22.4 204.9 68.0 24.7 23.1 10.7 21.3 29.9 9.7 455.1 24.1 23.5 37.7 4.0 33.4 24.5 35.7 36.2 39.4 83.5 26.3 94.9 30.9 5.0 28.1 62.4 69.8 97.0 60.4 84.0 35.7 22.2 0.1 0.3 1.3 0.1 1.1 1.5 0.4 0.2 0.3 0.0 0.1 4.7 0.1 4.2 121.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 95.0 1.8 2.2 3.7 0.5 0.3 0.3 0.0 0.8 0.2 1.6 773.0 34.1 2.3 57.8 0.1 0.4 33.3 8.1 0.1 0.0 9.1 1.4 15.3 3.8 0.0 0.1 0.4 0.3 1.8 0.0 0.1 0.2 0.0 48.5 537.8 0.8 0.5 0.9 0.2 3.4 6.3 6.8 1.6 6.7 0.1 54.8 263.9 219.2 19.8 419.6 18.9 26.7 2.2 46.6 154.0 32.7 36.3 68.6 392.0 40.3 702.3 88.6 2.1 224.2 20.3 21.4 21.9 25.3 18.0 22.2 24.7 23.1 24.1 26.3 28.1 22.2 672.9 16.0 37.9 0.7 24.4 0.0 0.5 0.0 4.0 0.0 4.8 4.6 23.3 1.5 3.1 9.2 0.0 0.5 50.1 0.0 0.0 0.8 0.9 1.1 1.1 468.2 0.0 17.9 1.2 0.2 4.0 22.0 0.0 1.6 8.8 0.0 275.3 3.0 45.8 0.0 1.2 0.0 0.0 110.4 0.0 1.1 2.5 143.9 0.0 47.8 93.8 0.3 26.8 0.5 1.3 0.1 0.0 1.9 109.1 1.3 0.0 0.5 7.3 1.2 0.0 6.9 15.8 0.1 0.5 1.6 0.0 0.8 21.2 4.3 0.1 1.0 PFKP "PFK-C, PFKF" ENSG00000067057 "Phosphofructokinase, platelet" Q01813 10 3066333-3137718 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 277.0" "Cell type enhanced" "Detected in many" "Early spermatids: 459.8;Late spermatids: 516.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018257, HPA056484" Uncertain Supported Cytosol No No 1900000 "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA018257: AB_10960391, HPA056484: AB_2683147" "unprognostic (1.16e-1)" "unprognostic (2.41e-3)" "unprognostic (5.79e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.55e-4)" "prognostic unfavorable (8.72e-6)" "unprognostic (1.36e-3)" "unprognostic (2.38e-1)" "unprognostic (8.51e-2)" "unprognostic (2.37e-2)" "unprognostic (8.82e-2)" "unprognostic (6.02e-3)" "unprognostic (2.60e-2)" "unprognostic (9.74e-2)" "unprognostic (2.06e-1)" "unprognostic (4.54e-3)" 35.0 11.5 41.6 41.5 39.3 14.4 23.5 13.8 49.9 26.3 61.7 43.8 48.8 55.5 5.6 67.1 34.9 34.1 128.6 60.4 65.0 44.6 4.7 19.1 32.5 30.7 50.9 19.1 15.9 15.2 29.9 15.5 58.0 35.6 30.7 277.0 39.8 62.0 70.4 40.3 59.6 44.1 8.3 19.1 36.8 141.1 47.0 29.7 38.5 21.0 21.2 64.7 42.8 31.7 314.8 420.2 25.9 0.6 26.8 56.9 336.9 187.2 66.6 186.2 222.8 444.5 320.4 37.0 147.8 134.9 174.9 243.0 141.7 292.3 173.1 102.1 111.0 132.0 189.1 24.2 65.2 53.7 203.4 27.0 61.2 190.0 96.0 273.7 367.8 153.7 37.0 1.3 195.7 239.8 182.5 44.4 42.9 133.9 149.3 138.8 46.9 150.1 185.7 115.9 69.5 64.7 133.7 111.0 172.0 307.8 93.7 80.3 449.2 124.6 65.3 380.5 199.3 195.4 200.1 135.7 331.0 98.0 78.5 30.8 8.5 2.9 26.8 4.2 21.2 13.7 26.2 25.0 14.5 15.3 9.6 15.4 1.3 26.7 1.6 22.5 37.6 16.5 41.6 39.3 13.8 49.9 60.4 65.0 30.7 50.9 58.0 8.3 47.0 31.7 30.5 3.2 7.0 128.6 14.8 28.7 58.5 96.8 14.8 40.4 10.3 7.7 147.4 8.6 57.9 64.4 54.2 7.8 16.3 72.6 43.0 115.7 459.8 41.2 9.0 36.0 37.2 10.3 49.4 10.8 205.8 25.9 35.7 63.8 55.9 25.8 14.6 0.7 33.9 42.1 25.9 23.1 124.1 7.6 31.4 516.3 7.5 14.3 19.6 15.0 15.4 113.1 16.5 16.1 6.7 116.8 57.2 6.8 14.2 80.9 53.2 5.9 62.6 133.4 13.1 43.2 34.6 149.4 3.5 25.1 22.6 26.5 28.8 11.2 28.9 64.2 PGM2L1 "BM32A, FLJ32029" ENSG00000165434 "Phosphoglucomutase 2 like 1" Q6PCE3 11 74330316-74398433 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 90.1;Exocrine glandular cells: 124.5;Pancreatic endocrine cells: 140.1;Respiratory ciliated cells: 95.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 16.6;LHCN-M2: 19.9;RH-30: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056995, HPA060948" Enhanced Approved Mitochondria No No 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 1: Pancreatic cells - Digestion" Mitochondria "HPA056995: AB_2683305, HPA060948: AB_2684394" "unprognostic (7.44e-3)" "unprognostic (1.33e-1)" "unprognostic (7.28e-3)" "unprognostic (8.91e-2)" "unprognostic (6.16e-2)" "unprognostic (1.55e-1)" "unprognostic (7.16e-6)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (5.97e-3)" "unprognostic (1.70e-2)" "unprognostic (2.98e-1)" "unprognostic (9.33e-3)" "unprognostic (3.71e-1)" "unprognostic (1.97e-1)" "unprognostic (3.04e-1)" "unprognostic (1.03e-2)" 1.9 2.6 17.6 3.7 22.1 3.2 1.9 0.0 21.5 4.9 0.0 3.2 1.3 4.4 0.8 1.0 3.2 3.3 1.1 23.1 16.2 1.6 1.0 1.8 3.0 1.9 4.5 0.9 3.1 0.7 3.9 1.1 2.2 2.9 3.5 2.6 2.6 1.3 5.9 0.7 1.5 4.0 0.3 1.5 2.1 1.3 5.7 8.1 2.7 11.1 2.7 6.4 1.9 7.8 2.7 3.8 14.5 2.7 4.3 1.9 0.4 3.5 2.6 3.0 3.3 1.4 6.8 0.3 8.5 2.3 5.3 1.3 2.9 0.7 2.8 1.1 1.5 2.1 2.0 1.1 0.5 2.4 3.2 1.0 0.7 6.8 1.2 3.2 16.6 5.0 2.8 1.8 19.9 0.3 9.9 2.1 2.9 2.0 3.3 3.1 18.9 0.1 7.8 0.5 0.7 2.9 5.7 1.3 2.6 3.9 0.2 0.4 14.0 6.6 6.0 2.7 3.7 2.4 3.8 0.3 0.6 3.4 1.6 1.2 0.3 0.5 0.9 0.3 1.3 1.1 1.6 1.1 0.2 0.8 1.5 0.8 0.3 1.4 0.2 0.8 3.9 0.5 17.6 22.1 0.0 21.5 23.1 16.2 1.9 4.5 2.2 0.3 5.7 7.8 19.6 6.4 6.4 8.5 20.9 7.6 41.2 14.3 10.8 23.9 26.5 19.4 7.3 17.2 30.2 9.2 16.7 0.6 17.6 13.8 5.9 37.4 14.1 28.1 23.5 32.1 11.9 47.5 90.1 124.5 5.3 21.0 7.1 25.5 8.2 16.1 29.3 1.0 5.4 8.4 64.8 16.2 18.3 23.0 21.6 3.6 2.5 9.9 16.0 20.6 4.6 4.4 12.3 14.6 7.1 140.1 9.3 3.8 13.4 50.4 4.2 5.3 95.4 11.0 26.3 21.3 16.7 34.2 21.2 9.0 5.3 0.1 25.0 8.8 20.9 55.6 PIK3C2A PI3K-C2alpha ENSG00000011405 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha" O00443 11 17077730-17207983 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Endocytosis, Exocytosis" "Kinase, Transferase" "Cataract, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037641, HPA037642" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Vesicles, Cytosol" "HPA037641: AB_10671878, HPA037642: AB_10697081" "unprognostic (2.35e-1)" "unprognostic (2.16e-2)" "unprognostic (3.71e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (6.63e-2)" "unprognostic (2.47e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (1.86e-2)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.20e-2)" "unprognostic (1.51e-1)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" 22.5 13.7 16.3 12.3 25.9 9.4 15.9 22.5 14.6 16.1 17.4 13.2 14.9 18.0 15.7 15.4 14.5 19.0 12.4 10.5 14.0 23.5 15.5 16.6 11.3 16.6 16.1 14.1 12.3 43.6 10.3 23.1 17.0 16.4 13.0 22.4 11.8 14.8 6.4 12.3 11.8 18.3 13.8 13.0 18.0 19.3 19.6 9.4 30.7 12.1 10.9 14.9 12.0 15.8 53.8 24.1 39.6 24.8 28.0 28.3 35.3 33.2 35.7 23.9 33.2 58.9 6.0 15.6 16.2 28.6 39.1 34.8 31.9 25.4 42.1 13.5 27.6 9.8 28.4 23.3 30.6 12.3 14.9 22.2 17.5 23.6 45.8 22.2 57.7 9.9 23.4 14.7 18.6 16.6 6.6 7.7 22.6 30.1 18.5 6.9 41.1 11.0 29.6 47.0 23.2 20.5 50.6 21.4 23.2 33.0 12.7 12.3 72.5 19.1 27.4 50.1 20.4 5.9 14.1 12.8 22.8 11.3 22.6 1.7 1.5 1.1 1.7 1.0 1.1 1.4 1.3 1.3 2.1 1.5 1.7 1.0 2.3 1.8 3.2 1.4 0.9 0.6 16.3 25.9 22.5 14.6 10.5 14.0 16.6 16.1 17.0 13.8 19.6 15.8 93.2 76.9 62.0 217.4 25.0 35.3 26.1 18.7 24.5 49.1 34.7 25.0 29.7 25.8 33.1 36.8 70.9 29.6 29.5 22.6 19.6 19.8 35.9 51.8 35.1 87.6 28.7 11.2 57.0 25.1 17.9 28.6 45.3 72.4 32.2 22.8 106.7 32.4 19.2 35.3 81.1 23.5 18.3 46.3 33.1 18.6 25.7 27.0 19.6 69.3 19.6 73.0 17.5 62.8 79.4 26.1 13.1 31.2 29.9 42.7 15.2 22.4 26.4 40.4 39.5 33.7 35.1 52.6 26.8 23.5 34.0 143.5 25.3 25.1 20.7 37.3 PIR ENSG00000087842 Pirin O00625 X 15384799-15493564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 96.1;Syncytiotrophoblasts: 85.6" "Cancer enhanced" "Detected in all" "melanoma: 48.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 292.4;HUVEC TERT2: 683.9;SK-MEL-30: 267.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000697 Approved Supported Cytosol NA NA 35000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA000697: AB_1079621" "unprognostic (3.46e-3)" "prognostic favorable (2.78e-4)" "unprognostic (4.26e-2)" "unprognostic (5.62e-3)" "unprognostic (4.16e-3)" "unprognostic (2.09e-2)" "unprognostic (6.70e-3)" "unprognostic (1.65e-1)" "unprognostic (1.08e-1)" "prognostic favorable (4.94e-4)" "unprognostic (3.78e-2)" "unprognostic (1.92e-1)" "prognostic unfavorable (6.11e-7)" "unprognostic (1.99e-2)" "unprognostic (8.90e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-1)" 19.1 19.9 20.2 5.2 23.7 5.7 15.4 23.5 24.3 12.4 21.2 10.0 6.5 11.7 15.3 29.6 13.3 11.4 17.3 18.7 22.9 11.4 21.0 15.4 2.7 23.0 22.6 13.1 3.3 4.9 11.3 10.5 22.8 10.1 6.7 7.9 10.3 14.2 14.7 11.9 8.6 10.4 22.5 20.1 11.9 6.2 22.5 6.2 15.7 6.4 7.1 30.4 17.4 25.7 14.3 76.6 45.0 66.3 26.1 29.0 14.4 4.2 26.5 11.0 24.5 21.5 118.9 0.0 147.2 12.3 292.4 96.7 52.8 21.3 4.0 0.0 11.6 8.4 80.7 63.9 33.4 4.4 29.8 8.3 72.3 41.9 14.4 19.2 683.9 0.0 6.4 19.2 9.4 29.8 3.3 4.1 48.4 62.1 47.7 0.0 8.9 37.9 22.2 136.0 17.2 47.5 36.7 20.5 267.9 76.8 42.4 26.7 43.2 5.9 11.0 28.5 8.7 9.1 39.6 0.3 28.6 15.8 59.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 20.2 23.7 23.5 24.3 18.7 22.9 23.0 22.6 22.8 22.5 22.5 25.7 24.5 0.0 4.1 0.0 1.1 8.7 24.3 48.4 10.8 2.8 4.2 4.8 5.8 10.0 19.4 1.8 0.0 96.1 0.0 4.8 9.8 5.9 0.6 59.6 3.8 40.3 11.3 11.6 0.2 2.5 12.8 15.6 15.8 20.0 0.0 21.7 22.9 24.0 22.0 20.2 0.2 3.4 38.7 6.4 3.4 4.0 37.6 4.1 40.9 0.0 11.9 30.8 0.0 0.0 0.0 3.4 1.7 28.6 3.6 18.1 5.9 12.0 38.0 4.8 13.1 8.4 11.3 0.6 3.5 34.5 12.6 85.6 0.6 56.2 4.3 50.9 PITPNA "PITPN, VIB1A" ENSG00000174238 "Phosphatidylinositol transfer protein alpha" Q00169 17 1517718-1562792 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000528 Uncertain Approved Vesicles,Cytosol NA NA 190000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" Cytosol Vesicles "HPA000528: AB_1079622" "unprognostic (1.54e-1)" "unprognostic (6.63e-2)" "unprognostic (2.43e-1)" "prognostic favorable (2.29e-4)" "unprognostic (7.88e-2)" "unprognostic (8.89e-3)" "unprognostic (2.37e-1)" "unprognostic (1.37e-1)" "unprognostic (7.33e-2)" "unprognostic (3.17e-2)" "prognostic favorable (1.80e-6)" "unprognostic (7.41e-2)" "prognostic favorable (9.35e-4)" "unprognostic (1.72e-1)" "unprognostic (1.23e-1)" "unprognostic (8.10e-2)" "unprognostic (6.81e-3)" 42.5 36.8 41.7 61.0 45.4 93.6 41.7 46.6 56.2 50.7 51.0 47.2 56.7 55.3 58.8 76.6 65.9 45.4 39.1 43.8 50.5 40.0 39.0 46.9 40.4 62.4 45.4 32.1 33.9 60.8 33.1 50.2 58.4 54.2 55.6 47.6 84.1 61.7 24.7 93.2 88.9 54.3 41.9 42.4 40.5 44.8 52.2 33.2 64.7 22.7 57.1 51.9 41.8 43.0 64.9 70.5 70.5 61.0 72.1 78.8 110.7 68.9 75.8 70.6 50.9 78.7 25.7 81.8 62.4 94.0 45.4 79.5 64.2 68.4 97.0 68.3 69.2 44.7 61.4 37.0 70.6 31.1 51.6 58.9 90.6 70.5 73.1 74.4 118.4 67.1 63.3 44.9 74.8 36.5 80.1 28.5 49.3 103.4 34.1 63.8 27.2 46.9 70.5 73.5 25.2 55.2 83.2 59.1 51.4 70.5 52.2 24.7 113.8 44.8 39.5 126.4 95.5 27.2 49.8 28.8 77.4 47.9 58.4 3.7 2.4 3.2 2.1 2.7 4.0 4.3 3.1 2.8 3.5 3.1 2.9 2.6 8.0 3.7 1.9 2.7 5.2 1.7 41.7 45.4 46.6 56.2 43.8 50.5 62.4 45.4 58.4 41.9 52.2 43.0 29.3 35.3 35.0 28.7 14.1 31.0 17.5 12.0 12.0 36.4 30.0 30.2 23.9 17.2 17.1 25.8 8.4 43.4 26.9 41.2 13.7 16.0 12.0 50.5 48.4 31.4 22.1 15.6 42.4 18.5 47.3 19.1 13.3 36.5 19.0 16.8 34.6 30.2 40.5 40.4 46.3 27.7 10.2 29.9 49.7 16.8 12.5 36.4 19.6 36.5 36.6 40.2 13.4 12.1 16.0 26.0 22.9 21.8 15.7 33.0 78.0 16.3 21.7 18.4 6.6 18.8 45.1 35.8 34.7 37.8 41.8 120.0 14.9 24.7 25.3 27.0 PKIA PRKACN1 ENSG00000171033 "CAMP-dependent protein kinase inhibitor alpha" P61925 8 78516340-78605267 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 1160.4;tongue: 953.8" "Cell type enhanced" "Detected in many" "Astrocytes: 104.8;Cardiomyocytes: 367.0;Excitatory neurons: 103.3;Inhibitory neurons: 78.2;Muller glia cells: 82.8;Oligodendrocyte precursor cells: 82.9" "Cancer enhanced" "Detected in many" "glioma: 15.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 21.4" "Lineage enriched" "Detected in many" 9 "T-cells: 21.4" "Cell line enhanced" "Detected in many" "HDLM-2: 63.9;HUVEC TERT2: 104.0;RT4: 100.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042791 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA042791: AB_10795761" "unprognostic (3.83e-3)" "unprognostic (1.89e-1)" "unprognostic (1.55e-2)" "unprognostic (5.59e-6)" "unprognostic (8.75e-2)" "unprognostic (1.56e-1)" "unprognostic (5.10e-3)" "unprognostic (1.65e-3)" "unprognostic (3.25e-2)" "unprognostic (2.58e-1)" "unprognostic (4.12e-1)" "unprognostic (1.00e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (5.41e-4)" "unprognostic (3.14e-1)" "unprognostic (1.38e-1)" "unprognostic (7.52e-3)" 2.5 9.5 44.4 5.6 49.3 2.7 4.1 41.4 49.2 2.2 11.9 3.5 1.2 3.1 3.0 21.5 5.3 8.2 185.9 49.8 44.0 4.7 0.2 8.6 7.6 25.4 34.3 5.8 1.4 108.1 8.0 1.6 36.0 20.3 2.8 33.7 6.2 5.3 1160.4 9.2 2.5 2.6 35.2 4.1 1.6 1.3 48.1 26.3 34.2 953.8 11.0 9.5 3.6 36.2 0.6 0.3 34.2 0.0 18.5 4.8 0.2 32.1 6.3 3.4 7.2 0.0 5.3 14.8 0.2 4.8 3.3 0.5 11.3 10.3 22.3 63.9 24.6 18.5 3.7 0.2 1.2 0.0 10.3 7.7 1.5 0.0 9.6 45.5 104.0 19.8 0.0 15.8 51.4 5.4 28.3 0.0 8.1 0.0 35.3 0.0 29.3 0.0 18.7 100.2 16.6 32.5 4.1 26.4 0.0 8.9 0.0 0.1 41.2 7.8 6.4 1.8 19.2 6.5 6.9 4.9 36.9 0.1 9.8 0.0 0.0 0.0 0.5 0.1 0.4 2.3 9.1 1.8 0.1 2.2 7.7 4.6 0.4 1.7 0.1 0.2 21.4 2.5 44.4 49.3 41.4 49.2 49.8 44.0 25.4 34.3 36.0 35.2 48.1 36.2 0.6 3.2 2.8 104.8 9.8 5.9 8.8 4.5 19.9 40.2 2.6 6.5 367.0 0.0 2.0 1.8 2.1 3.1 2.7 0.4 1.9 0.0 13.9 0.9 0.2 9.1 10.2 4.2 103.3 0.2 2.8 12.3 0.0 1.3 5.7 18.6 2.5 0.0 0.7 58.9 78.2 0.8 6.1 0.0 1.1 5.9 0.0 3.9 3.6 15.0 0.5 82.8 0.0 82.9 17.9 1.5 0.1 0.4 2.3 6.1 0.0 0.1 1.0 6.9 0.0 22.9 4.8 0.4 0.6 13.9 13.8 3.4 8.0 0.1 0.3 3.6 PLA2G4C cPLA2-gamma ENSG00000105499 "Phospholipase A2 group IVC" Q9UP65 19 48047843-48110817 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid metabolism, Phospholipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 78.8;skeletal muscle: 66.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 77.1;Cone photoreceptor cells: 66.7;Muller glia cells: 57.1;Oligodendrocytes: 137.1;Rod photoreceptor cells: 153.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 5.7" "Group enriched" "Detected in many" 4 "B-cells: 4.0;monocytes: 5.7" "Cell line enhanced" "Detected in many" "HHSteC: 13.1;TIME: 19.4" "Not detected" "Not detected" HPA043083 Approved Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA043083: AB_10795714" "unprognostic (1.27e-1)" "unprognostic (3.88e-2)" "unprognostic (4.18e-2)" "unprognostic (2.82e-2)" "unprognostic (7.37e-2)" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (6.53e-2)" "unprognostic (8.30e-2)" "unprognostic (1.94e-1)" "unprognostic (5.11e-3)" "unprognostic (1.90e-1)" "unprognostic (4.66e-2)" "unprognostic (9.45e-2)" "unprognostic (2.28e-3)" "unprognostic (1.87e-1)" "unprognostic (9.01e-2)" 5.1 17.3 13.8 5.5 23.8 0.3 4.3 20.8 20.5 4.6 4.5 6.5 6.3 8.6 3.0 4.3 5.1 5.8 25.1 14.1 18.2 6.1 4.7 8.0 10.2 24.8 23.5 1.7 4.9 12.8 6.6 5.1 26.7 6.8 3.3 78.8 4.1 8.0 66.7 6.4 8.5 10.3 14.3 11.2 3.3 2.8 21.1 4.7 4.9 41.2 5.6 5.1 2.6 41.5 0.7 1.3 0.0 0.3 5.7 3.0 0.1 1.3 8.5 1.4 3.4 0.0 2.1 0.0 1.8 3.7 2.7 0.3 0.0 0.2 2.2 0.9 0.2 0.0 0.5 1.3 13.1 0.0 1.9 0.6 0.3 0.7 5.7 2.6 4.9 0.1 0.0 8.0 2.2 2.2 0.1 0.2 0.1 1.0 0.1 0.1 2.0 0.8 2.7 0.6 0.9 0.1 1.5 2.9 7.1 4.3 0.8 2.2 19.4 2.2 0.8 2.8 1.0 0.5 1.8 0.2 1.9 0.0 4.8 0.0 2.1 0.0 0.1 5.7 0.4 4.0 0.5 0.0 1.2 0.9 0.0 0.0 0.0 1.1 1.4 0.8 0.1 1.4 13.8 23.8 20.8 20.5 14.1 18.2 24.8 23.5 26.7 14.3 21.1 41.5 7.2 3.2 1.7 30.7 2.4 2.8 1.0 1.5 1.2 77.1 2.4 2.9 35.3 5.7 0.5 0.0 66.7 0.2 0.6 1.2 1.9 13.0 0.3 0.5 4.6 14.3 0.0 0.0 31.6 2.9 0.2 7.4 1.1 0.7 0.0 0.1 4.6 2.0 5.6 33.7 34.7 1.6 18.3 1.2 11.1 0.2 0.6 4.9 7.2 15.0 3.1 57.1 1.0 25.1 137.1 2.7 1.4 7.9 0.7 2.5 5.7 5.2 0.2 153.8 13.1 18.0 9.9 0.9 1.0 0.2 3.0 0.1 1.1 1.6 0.3 0.4 PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 39.1;thyroid gland: 41.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Excitatory neurons: 34.6;Inhibitory neurons: 43.5;Muller glia cells: 33.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 14.5;ASC TERT1: 19.5;BJ hTERT+: 16.2;hTERT-RPE1: 26.3;TIME: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" NA NA 960000 "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "CAB068217: AB_2665660, CAB068218: AB_2665661" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (4.91e-3)" "unprognostic (6.01e-2)" "unprognostic (9.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (9.38e-3)" "unprognostic (4.30e-3)" "unprognostic (2.82e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.62e-1)" "unprognostic (6.58e-2)" "unprognostic (2.02e-1)" 4.7 2.9 0.7 1.4 0.8 0.0 14.9 9.7 2.2 6.9 1.7 3.1 3.9 8.8 2.9 4.7 5.4 9.3 2.5 0.5 1.5 20.8 1.4 2.6 1.9 2.0 2.7 10.8 0.6 19.7 2.2 3.8 2.1 3.1 3.2 5.6 39.1 2.9 0.5 10.9 6.1 6.9 1.4 5.1 1.6 1.0 2.5 0.6 41.9 1.3 2.7 3.9 6.0 1.0 0.2 1.6 0.6 0.0 14.5 19.5 0.1 6.8 16.2 1.3 1.8 0.0 3.4 0.0 0.4 7.2 1.4 3.3 0.1 5.0 1.4 0.0 0.0 0.0 11.8 0.0 1.2 0.0 0.0 7.9 5.4 1.9 2.1 26.3 9.3 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.2 0.1 2.6 0.0 0.0 0.0 1.4 0.7 0.0 0.0 11.8 2.2 0.0 1.7 2.6 0.2 47.3 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.8 9.7 2.2 0.5 1.5 2.0 2.7 2.1 1.4 2.5 1.0 11.1 6.4 2.8 20.9 0.1 9.4 2.7 18.1 21.6 2.7 22.1 14.5 4.1 5.7 11.3 33.1 0.0 7.3 0.5 1.7 0.0 0.6 0.1 5.6 22.0 4.0 1.2 0.0 34.6 2.0 1.3 14.8 0.0 9.4 1.3 9.6 8.6 0.0 0.6 16.8 43.5 7.2 4.1 0.0 2.1 1.4 16.1 0.5 7.2 25.3 0.0 33.5 0.0 5.5 1.8 5.1 11.3 16.6 0.1 2.6 15.6 2.3 8.1 1.4 6.6 3.4 4.8 0.1 1.0 9.3 5.4 1.5 0.6 6.3 7.5 3.0 PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600404-171810950 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 519.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 57.5;SK-MEL-30: 31.1;TIME: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004527, HPA042396, HPA066938" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "CAB004527: AB_677324, HPA042396: AB_2677977, HPA066938: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.76e-6)" 7.8 26.4 9.2 6.6 24.7 7.8 7.5 18.4 13.6 10.4 4.5 14.6 46.9 6.2 2.8 33.0 6.4 86.8 24.4 10.5 14.3 12.0 33.7 4.7 9.1 24.8 22.0 24.2 21.2 1.6 2.3 10.7 23.5 3.4 14.7 0.5 13.8 6.0 2.5 29.2 43.9 4.8 14.7 15.7 8.2 5.0 19.0 4.1 3.7 6.8 10.8 5.1 12.4 41.4 4.5 7.2 3.7 1.4 11.2 12.6 7.7 2.3 9.9 3.5 4.3 1.1 6.4 0.0 17.0 0.9 24.0 15.2 0.6 2.0 5.7 3.6 3.2 4.2 11.5 26.1 4.9 7.3 18.9 4.9 10.9 4.2 2.0 10.0 57.5 1.2 2.8 0.0 0.9 1.3 0.0 6.4 0.8 11.9 5.1 0.2 1.5 0.1 8.9 1.8 0.1 0.1 7.9 4.7 31.1 5.1 9.0 9.7 50.7 1.5 5.7 4.0 2.5 9.6 8.2 0.1 6.7 8.6 1.9 8.3 1.8 2.3 0.3 1.1 2.6 0.0 0.2 0.6 0.6 0.0 0.0 0.1 1.0 2.2 0.4 0.0 0.8 0.6 9.2 24.7 18.4 13.6 10.5 14.3 24.8 22.0 23.5 14.7 19.0 41.4 7.7 0.0 4.7 2.0 0.9 7.1 3.4 11.0 10.8 0.4 4.9 5.6 33.6 57.2 11.1 1.8 0.0 3.0 1.9 37.5 3.9 8.4 13.1 1.0 4.8 7.4 4.2 6.3 8.9 3.4 3.7 15.7 27.0 1.3 27.9 10.4 6.4 15.9 20.0 0.0 12.1 23.6 6.1 13.2 2.4 9.5 10.5 10.2 12.4 98.4 5.4 0.0 1.0 12.5 519.6 2.4 18.3 4.5 3.4 0.7 38.3 48.0 9.9 0.1 19.7 3.8 8.4 6.1 5.3 93.5 34.9 2.3 2.3 12.1 17.8 4.7 PLD2 ENSG00000129219 "Phospholipase D2" O14939 17 4807152-4823434 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013397 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA013397: AB_1855328" "unprognostic (1.87e-1)" "unprognostic (3.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (2.90e-2)" "unprognostic (3.85e-3)" "unprognostic (3.64e-1)" "unprognostic (6.15e-3)" "unprognostic (2.58e-3)" "unprognostic (1.25e-1)" "unprognostic (8.10e-3)" "unprognostic (1.08e-1)" "unprognostic (2.95e-1)" "unprognostic (1.91e-1)" "unprognostic (1.85e-1)" "unprognostic (5.48e-2)" 17.4 8.1 19.9 10.0 22.8 2.6 17.9 21.5 21.3 32.3 16.0 11.2 6.9 15.2 6.9 63.3 14.5 14.3 10.2 19.4 21.9 11.7 12.1 16.1 9.5 30.4 24.3 21.5 14.0 8.9 10.4 14.2 22.3 19.0 9.0 4.9 22.6 14.5 5.1 33.5 10.7 13.4 24.7 12.6 11.3 4.3 24.5 12.9 11.9 6.7 18.0 15.0 37.1 23.5 13.0 20.2 17.4 18.8 15.0 19.9 20.0 8.2 17.2 14.2 11.3 21.7 15.1 5.6 9.4 21.3 5.3 30.2 13.9 18.3 12.8 7.3 7.0 1.8 15.7 13.2 10.8 0.1 13.3 29.4 27.0 12.8 12.1 20.0 33.2 3.9 2.1 5.2 12.0 9.9 0.7 2.4 9.2 10.7 8.7 6.3 11.2 1.4 12.9 20.9 5.9 10.2 15.5 18.1 11.6 14.1 13.0 3.0 26.1 9.4 9.5 21.6 12.8 4.6 2.3 1.2 14.4 2.6 5.6 4.0 4.8 1.2 1.2 4.9 0.9 1.6 1.3 0.9 3.6 0.9 0.3 0.4 0.3 0.8 5.4 1.6 2.3 2.4 19.9 22.8 21.5 21.3 19.4 21.9 30.4 24.3 22.3 24.7 24.5 23.5 10.9 0.0 1.1 26.8 2.8 12.6 9.8 11.2 14.8 1.2 11.6 10.3 2.8 7.2 8.9 1.8 0.0 21.8 2.6 7.1 1.9 8.7 0.0 2.5 4.6 12.0 1.2 0.0 1.6 11.5 14.8 7.7 10.7 5.4 5.7 12.0 12.8 2.9 12.9 0.0 2.7 7.0 6.1 8.1 13.8 0.5 9.6 10.7 7.2 5.6 19.9 7.8 1.0 3.5 5.8 10.4 10.2 8.6 1.4 14.0 3.8 4.2 9.2 1.7 0.0 4.1 5.0 0.2 2.7 9.8 12.1 17.4 3.1 7.2 5.7 10.5 PLEKHG5 "GEF720, KIAA0720, Syx, Tech" ENSG00000171680 "Pleckstrin homology and RhoGEF domain containing G5" O94827 1 6467122-6520074 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.4;skin 1: 102.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 57.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 32.1;TIME: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049570 Uncertain Approved Nucleoplasm NA NA "Cluster 61: Skin - Cornification" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA049570: AB_2680818" "unprognostic (5.59e-2)" "unprognostic (1.33e-1)" "unprognostic (2.47e-1)" "unprognostic (2.81e-1)" "unprognostic (1.50e-3)" "unprognostic (5.10e-2)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (4.40e-2)" "unprognostic (1.02e-2)" "unprognostic (4.85e-1)" "unprognostic (2.70e-2)" "unprognostic (1.28e-3)" "unprognostic (4.85e-1)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (4.85e-2)" 18.7 15.0 4.4 2.9 2.6 0.6 12.0 57.4 16.6 14.0 0.0 7.3 6.4 7.5 1.9 21.6 8.6 7.3 16.4 13.0 0.0 6.5 1.8 6.0 5.0 0.0 0.0 7.5 5.1 4.4 43.3 12.4 1.8 9.9 3.5 3.4 9.3 7.2 6.8 102.5 8.4 3.9 0.0 50.9 4.4 5.4 0.0 2.0 7.2 3.0 3.3 5.9 14.3 0.0 7.1 2.7 11.9 9.4 1.5 4.2 3.1 8.4 7.0 3.2 2.1 6.9 18.8 0.3 22.6 2.8 4.9 22.6 2.2 23.7 1.3 16.5 3.0 0.0 15.1 2.9 1.9 0.0 1.3 5.5 10.2 8.1 12.5 17.4 24.9 1.7 0.0 1.5 0.6 5.0 0.5 32.1 4.9 2.3 23.8 0.1 2.7 2.3 6.3 3.1 10.5 25.2 1.1 8.2 1.5 5.3 8.2 0.5 30.3 8.1 5.0 0.0 6.6 0.1 0.0 2.4 9.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.6 57.4 16.6 13.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 10.6 0.0 1.5 1.0 0.2 7.4 2.3 4.7 8.0 1.4 1.4 2.2 4.1 1.5 3.6 3.7 2.1 2.6 0.1 4.2 0.0 1.3 8.6 2.5 5.9 9.8 3.5 0.4 17.4 1.3 4.0 1.9 3.1 3.2 0.0 4.0 7.5 0.3 5.3 1.7 9.6 6.4 6.1 0.8 1.3 5.7 1.8 2.4 0.0 7.5 0.0 9.7 0.0 2.0 1.2 5.1 5.6 8.6 0.4 3.8 4.1 0.4 2.7 1.5 13.1 2.1 1.7 2.1 5.1 10.8 14.5 1.9 0.7 2.5 2.8 5.8 PLK3 "CNK, FNK, PRK" ENSG00000173846 "Polo like kinase 3" Q9H4B4 1 44800377-44805990 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Paneth cells: 116.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060318 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "HPA060318: AB_2684252" "unprognostic (1.06e-1)" "unprognostic (8.71e-2)" "unprognostic (3.69e-2)" "unprognostic (3.51e-3)" "unprognostic (3.09e-2)" "unprognostic (4.72e-2)" "unprognostic (1.02e-1)" "unprognostic (1.59e-1)" "unprognostic (5.12e-3)" "unprognostic (6.78e-2)" "unprognostic (7.67e-3)" "unprognostic (2.79e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (5.06e-2)" "unprognostic (1.35e-1)" 13.6 6.4 3.2 10.7 3.6 13.8 8.9 4.0 5.3 8.7 8.1 4.9 3.3 8.1 2.8 19.2 7.4 17.3 6.3 3.6 6.0 5.8 7.1 12.9 9.0 9.3 7.1 6.6 8.9 7.1 7.5 6.7 6.7 5.6 2.9 0.4 6.7 3.3 2.8 16.1 6.5 4.9 5.8 7.7 5.4 2.1 5.4 5.4 7.3 2.4 5.8 18.0 8.7 7.2 7.2 4.1 6.6 3.4 4.7 15.0 12.3 15.7 20.8 5.9 5.8 2.5 9.9 8.1 6.5 12.9 18.7 6.5 3.7 21.4 3.2 13.5 0.7 9.1 2.6 6.2 22.5 2.9 11.7 11.8 12.3 17.4 16.1 20.0 17.8 3.0 4.9 3.6 13.0 4.6 6.2 2.7 4.5 4.0 5.5 7.8 4.3 13.3 20.3 2.4 5.0 3.2 4.5 8.3 17.6 10.1 0.6 2.8 23.3 3.6 9.4 7.5 9.7 9.5 4.7 2.8 8.0 5.2 7.2 0.0 4.0 1.0 1.9 5.9 2.1 1.4 11.6 4.7 5.0 1.2 12.4 5.8 4.7 0.8 6.3 2.0 14.0 4.4 3.2 3.6 4.0 5.3 3.6 6.0 9.3 7.1 6.7 5.8 5.4 7.2 55.7 12.8 35.1 1.3 32.2 44.1 60.5 23.3 32.5 7.1 58.4 33.7 3.4 32.9 15.8 5.5 2.1 19.0 32.2 77.7 0.0 18.3 0.8 41.9 27.6 43.5 53.0 2.7 3.6 13.0 22.9 36.7 109.6 67.5 78.7 12.0 32.5 6.7 36.9 6.7 6.3 53.0 2.0 37.7 60.3 0.7 9.9 72.5 12.4 10.3 9.8 7.4 1.0 1.5 2.0 24.3 116.8 5.3 31.4 25.8 47.3 3.3 14.7 10.2 26.3 58.5 30.5 2.5 4.5 37.2 33.5 59.2 65.2 17.0 46.3 58.9 PLSCR3 ENSG00000187838 "Phospholipid scramblase 3" Q9NRY6 17 7389727-7394842 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 3.0;Ductal cells: 5.8;Exocrine glandular cells: 3.6;monocytes: 2.0;Pancreatic endocrine cells: 8.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048387, HPA068609" Supported Supported Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA048387: AB_2680381, HPA068609: AB_2686011" "unprognostic (1.86e-2)" "unprognostic (5.29e-2)" "unprognostic (2.29e-2)" "unprognostic (1.56e-2)" "unprognostic (4.36e-2)" "unprognostic (5.02e-2)" "unprognostic (2.27e-2)" "unprognostic (9.71e-2)" "unprognostic (1.75e-3)" "unprognostic (1.91e-1)" "unprognostic (1.11e-2)" "unprognostic (1.77e-2)" "unprognostic (2.11e-5)" "unprognostic (1.24e-2)" "unprognostic (1.48e-1)" "unprognostic (1.97e-1)" "unprognostic (2.55e-2)" 39.5 21.1 7.4 11.0 7.5 3.3 35.0 7.0 8.5 46.2 7.2 27.1 3.1 44.5 5.9 37.4 29.4 6.5 32.0 6.8 7.4 23.5 14.4 32.8 10.5 8.5 7.3 30.5 16.7 5.6 16.4 7.0 7.6 24.7 3.4 1.2 22.9 8.0 21.2 35.2 21.9 12.3 7.4 40.7 21.9 6.1 8.1 6.4 22.8 11.1 10.5 34.8 38.1 7.7 26.7 6.6 5.7 17.2 19.4 32.8 6.8 24.1 22.1 21.3 19.3 9.8 6.6 7.3 19.4 35.1 9.0 37.6 7.0 41.4 10.9 19.0 4.0 6.7 9.2 6.0 23.6 2.5 8.2 22.6 25.4 20.7 30.1 32.0 32.3 14.5 4.1 5.6 27.1 14.3 7.7 2.0 5.1 7.1 18.3 15.1 4.3 8.3 20.1 17.7 4.7 15.6 13.9 8.8 5.9 5.0 16.0 1.3 53.2 13.9 14.5 15.7 10.3 6.2 7.4 3.0 22.4 8.4 15.9 7.0 24.5 2.8 39.5 34.1 40.8 32.2 72.8 40.7 24.1 32.5 59.2 36.1 2.6 18.0 30.2 2.8 83.5 33.3 7.4 7.5 7.0 8.5 6.8 7.4 8.5 7.3 7.6 7.4 8.1 7.7 1.0 3.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 5.8 0.0 0.1 1.0 1.0 0.0 0.0 0.0 3.6 0.3 1.0 0.0 0.1 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 PLSCR4 ENSG00000114698 "Phospholipid scramblase 4" Q9NRQ2 3 146192335-146251179 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 77.3;Astrocytes: 151.1;Endothelial cells: 63.4;Hepatic stellate cells: 110.3;Oligodendrocyte precursor cells: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 60.5;ASC TERT1: 48.2;hTERT-RPE1: 62.1;HUVEC TERT2: 50.8;TIME: 106.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002276 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA002276: AB_1855479" "unprognostic (3.73e-3)" "unprognostic (4.03e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.62e-1)" "unprognostic (6.77e-3)" "unprognostic (1.19e-1)" "unprognostic (4.36e-2)" "unprognostic (7.33e-2)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (4.13e-4)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" "unprognostic (8.13e-3)" "unprognostic (2.97e-3)" 60.2 43.8 30.2 9.4 28.2 2.3 41.9 30.9 32.5 28.9 11.6 27.4 6.8 30.1 15.7 23.2 41.2 45.6 28.0 28.7 38.5 25.3 69.0 37.4 10.5 39.3 44.0 36.4 20.5 4.3 11.2 56.4 32.6 13.8 25.2 13.7 23.6 25.8 7.4 16.1 13.6 33.7 36.9 30.1 14.4 21.6 41.8 6.6 31.2 18.8 6.7 19.8 25.5 32.2 0.0 9.9 1.7 0.0 60.5 48.2 0.3 11.5 15.7 5.0 10.9 1.0 12.6 0.0 12.3 21.0 5.0 1.4 2.4 1.1 2.8 0.1 0.1 5.0 7.9 1.3 28.1 0.1 1.3 29.6 1.6 10.4 3.0 62.1 50.8 0.0 0.2 0.9 7.4 0.3 0.0 0.1 2.1 5.1 3.4 0.0 0.8 0.0 0.1 0.0 0.6 0.0 20.1 0.1 3.9 2.5 0.7 0.6 106.4 10.4 2.6 23.6 2.1 0.3 0.0 0.0 2.6 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.2 28.2 30.9 32.5 28.7 38.5 39.3 44.0 32.6 36.9 41.8 32.2 77.3 3.2 10.3 151.1 1.0 10.8 5.6 0.8 12.0 0.6 10.2 8.6 4.1 25.8 6.0 3.7 0.0 0.7 0.3 27.4 0.0 8.2 1.1 3.6 11.6 63.4 10.3 15.6 1.7 11.6 0.5 57.1 2.0 1.5 1.3 7.0 110.3 44.1 0.8 0.0 0.6 11.7 0.0 7.1 11.8 3.8 42.9 1.1 3.6 40.3 0.1 51.4 0.0 61.3 0.6 4.7 13.3 32.4 2.8 2.6 6.4 28.3 6.4 1.5 0.0 18.9 23.6 1.2 0.9 4.8 8.7 0.8 1.8 20.0 8.1 2.7 PLXNA2 "FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2" ENSG00000076356 "Plexin A2" O75051 1 208022242-208244384 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 35.1" "Cell type enhanced" "Detected in many" "Astrocytes: 100.6;Excitatory neurons: 134.7;Horizontal cells: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 52.8;HaCaT: 55.4;HUVEC TERT2: 70.3;TIME: 162.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009763 Approved NA NA 1400000 "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB009763: AB_2166388" "unprognostic (8.25e-2)" "unprognostic (3.91e-2)" "unprognostic (8.85e-2)" "unprognostic (2.77e-2)" "unprognostic (8.66e-2)" "unprognostic (2.07e-1)" "unprognostic (1.97e-2)" "unprognostic (4.84e-2)" "unprognostic (6.88e-3)" "unprognostic (7.06e-2)" "unprognostic (2.61e-1)" "unprognostic (8.41e-2)" "unprognostic (4.49e-3)" "unprognostic (1.26e-1)" "unprognostic (5.40e-2)" "unprognostic (1.27e-2)" "unprognostic (2.40e-1)" 7.9 1.4 6.6 2.1 9.1 0.4 4.9 10.5 11.2 3.9 19.0 9.0 6.8 6.0 2.0 15.4 5.2 4.0 8.8 10.0 1.6 3.4 2.4 14.3 1.0 2.2 7.8 13.8 35.1 1.3 3.0 8.5 3.2 4.1 7.2 3.7 4.1 3.1 9.6 9.5 7.7 5.9 4.5 1.3 9.0 0.6 2.7 4.3 6.8 9.4 2.4 9.4 6.3 7.7 6.4 3.7 6.9 1.0 7.6 14.7 52.8 5.0 3.1 3.0 0.5 0.2 0.1 0.0 9.8 3.9 1.3 55.4 0.1 31.4 0.9 1.9 1.1 0.0 6.9 3.7 3.2 0.0 0.2 3.9 10.0 2.4 14.2 2.0 70.3 0.0 0.0 0.0 30.7 0.7 0.1 0.1 1.1 11.2 9.4 0.0 7.0 4.7 5.7 4.0 2.0 12.5 5.9 4.5 5.5 13.3 0.5 0.0 162.9 1.1 1.7 5.9 10.4 0.3 0.0 0.0 6.5 0.0 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 9.1 10.5 11.2 10.0 1.6 2.2 7.8 3.2 4.5 2.7 7.7 50.7 28.9 28.6 100.6 1.7 4.8 16.2 12.9 30.1 12.7 2.9 2.2 5.8 7.2 25.6 0.0 2.1 5.3 0.8 64.6 1.9 4.2 0.9 13.8 0.9 48.1 9.1 0.0 134.7 15.3 2.5 9.6 44.4 9.5 6.3 1.1 36.8 5.9 3.3 249.0 62.9 29.0 8.2 5.5 6.0 0.6 9.9 4.4 5.4 54.4 1.4 0.4 1.0 44.7 3.1 23.3 52.2 6.8 1.7 8.2 33.6 2.2 8.5 2.7 6.6 26.3 8.1 1.9 1.0 41.1 10.5 1.9 1.1 1.4 26.5 22.7 PLXNA4 "DKFZp434G0625PRO34003, FAYV2820, KIAA1550, PLXNA4A, PLXNA4B" ENSG00000221866 "Plexin A4" Q9HCM2 7 132123332-132648688 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.8;brain: 29.1" "Group enriched" "Detected in many" 4 "Excitatory neurons: 235.3;Inhibitory neurons: 261.3" "Cancer enhanced" "Detected in many" "glioma: 3.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 29.1;hippocampal formation: 26.0" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.6" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.6" "Cell line enhanced" "Detected in some" "ASC diff: 25.2;HMC-1: 17.1;hTERT-RPE1: 22.1;RH-30: 18.5;TIME: 57.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029919, HPA052141, HPA075592" Approved Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA029919: AB_10671093, HPA052141: AB_2681745, HPA075592: AB_2732297" "unprognostic (2.05e-2)" "unprognostic (3.59e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.61e-6)" "unprognostic (5.76e-2)" "unprognostic (1.21e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-2)" "unprognostic (2.19e-1)" "unprognostic (7.99e-2)" "unprognostic (7.64e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-5)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (5.90e-2)" "unprognostic (1.42e-3)" 13.8 2.4 4.2 1.6 5.6 0.3 7.6 0.1 29.1 8.4 0.0 1.5 0.4 1.5 0.2 3.8 2.0 1.9 3.9 26.0 1.3 0.7 0.3 1.2 1.0 2.3 0.1 3.6 0.4 0.1 1.0 3.5 1.8 0.5 0.7 4.8 0.4 0.9 0.7 2.2 0.8 2.6 0.9 1.5 1.6 1.1 1.6 0.2 1.5 3.1 0.3 1.0 0.7 4.4 0.0 0.1 0.2 0.0 25.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 17.1 0.2 0.0 0.1 0.0 22.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.0 18.5 2.0 0.0 0.0 0.4 9.6 0.0 0.0 0.0 0.2 0.0 0.0 57.6 5.7 0.2 1.3 0.5 0.0 0.0 0.0 5.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.6 0.0 0.0 4.2 5.6 0.1 29.1 26.0 1.3 2.3 0.1 1.8 0.9 1.6 4.4 2.5 0.0 0.0 5.2 0.6 0.6 0.2 0.0 0.0 22.4 2.2 0.1 10.9 0.0 0.0 12.9 16.7 0.1 17.4 0.0 0.0 0.0 14.0 2.1 3.0 2.7 1.2 0.0 235.3 0.0 0.1 7.4 1.1 5.0 1.3 1.6 5.0 0.2 0.1 0.0 261.3 0.1 0.0 0.0 1.1 9.8 14.0 0.7 7.2 10.3 0.0 11.3 2.1 51.8 3.7 0.8 0.0 7.2 0.7 0.1 0.0 0.5 0.0 1.5 0.0 0.7 1.1 0.2 0.3 0.1 1.3 0.0 1.7 0.4 0.1 0.4 PLXND1 KIAA0620 ENSG00000004399 "Plexin D1" Q9Y4D7 3 129555214-129606676 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 107.3;Endothelial cells: 102.1;Hepatic stellate cells: 132.1;Hofbauer cells: 81.5;Kupffer cells: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 10.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 392.3;HSkMC: 286.1;HUVEC TERT2: 346.1;TIME: 414.4" "Group enriched" "Detected in all" 4 "amygdala: 36.6;basal ganglia: 33.1;cerebral cortex: 27.4;hippocampal formation: 26.3" "Low region specificity" "Detected in all" CAB020819 Approved NA NA 120000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB020819: " "unprognostic (8.97e-3)" "unprognostic (1.95e-1)" "unprognostic (6.30e-2)" "unprognostic (8.35e-2)" "unprognostic (1.28e-2)" "unprognostic (3.00e-3)" "unprognostic (6.35e-2)" "unprognostic (4.51e-2)" "unprognostic (3.69e-1)" "unprognostic (3.02e-3)" "unprognostic (3.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (5.93e-7)" "unprognostic (1.30e-1)" "unprognostic (3.21e-2)" "unprognostic (3.17e-2)" "unprognostic (1.00e-2)" 72.6 22.1 32.0 37.4 38.1 26.5 47.4 36.2 35.6 58.4 26.1 19.5 6.0 33.5 17.6 21.5 35.0 39.4 39.8 29.3 34.2 24.7 18.3 67.5 34.7 48.7 43.5 16.3 13.9 18.0 11.1 112.4 43.8 19.0 16.9 3.5 13.3 27.0 12.9 19.5 20.9 52.6 38.8 33.6 15.8 10.8 49.0 62.7 29.5 39.8 23.2 37.1 26.8 43.2 10.0 57.7 47.4 16.3 392.3 167.9 98.4 42.8 123.1 25.5 29.5 13.4 8.1 2.1 179.9 152.9 13.2 0.6 25.9 0.6 7.5 1.9 3.2 40.7 30.2 61.4 44.8 13.5 11.0 286.1 1.7 26.4 2.8 36.6 346.1 2.1 14.5 1.5 34.8 31.0 2.4 44.2 11.8 2.4 8.0 47.4 32.0 51.8 10.2 2.3 27.6 1.1 11.0 3.5 15.9 107.6 15.5 59.7 414.4 21.5 28.5 0.6 32.4 1.9 2.2 19.9 7.5 29.2 19.0 0.0 10.7 0.0 1.7 5.1 6.8 0.0 1.2 1.4 2.9 0.0 0.0 0.1 0.2 3.1 5.2 3.6 0.0 1.7 32.0 38.1 36.2 35.6 29.3 34.2 48.7 43.5 43.8 38.8 49.0 43.2 107.3 3.2 27.2 12.4 3.6 8.0 0.4 2.1 0.6 0.1 7.6 3.4 10.6 5.7 3.1 0.0 0.0 7.1 16.9 0.2 0.0 1.4 1.4 3.7 52.5 102.1 13.1 12.6 10.4 3.5 16.4 19.5 5.6 6.2 22.2 1.3 132.1 7.7 81.5 0.0 0.6 3.2 6.1 75.6 31.8 1.8 38.8 41.7 8.8 27.2 29.4 6.5 10.3 0.5 27.7 2.7 0.1 13.9 12.9 0.5 0.0 0.3 1.2 0.3 32.9 14.4 37.1 0.6 4.0 1.5 4.4 5.3 14.4 49.5 0.5 0.6 POLR3GL "flj32422, MGC3200" ENSG00000121851 "RNA polymerase III subunit GL" Q9BT43 1 145964690-145978848 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 196.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA027288 Uncertain NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA027288: AB_10602119" "prognostic favorable (2.96e-4)" "unprognostic (3.58e-3)" "unprognostic (1.55e-2)" "prognostic favorable (6.52e-5)" "unprognostic (2.88e-1)" "unprognostic (1.19e-1)" "unprognostic (2.23e-1)" "unprognostic (1.37e-2)" "unprognostic (4.15e-2)" "unprognostic (2.11e-1)" "unprognostic (5.98e-3)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (9.96e-2)" "unprognostic (3.61e-1)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" 50.3 42.0 33.4 26.5 33.9 28.7 41.9 32.7 42.9 29.8 33.9 41.2 19.8 30.2 27.7 20.1 31.4 21.0 67.7 32.6 35.9 31.7 55.2 31.7 40.5 34.9 33.8 36.2 21.1 31.4 33.3 19.8 33.6 28.7 25.0 28.3 26.2 24.6 139.8 26.9 36.7 24.4 33.1 46.6 33.6 19.8 34.4 41.1 33.7 66.1 41.6 32.7 25.1 33.9 28.5 12.6 28.6 26.4 70.3 78.8 6.9 28.3 43.9 19.0 28.6 3.9 31.0 60.9 41.4 39.6 15.4 8.6 14.1 27.7 28.8 66.8 15.5 40.6 10.6 19.8 43.2 41.1 55.3 60.1 18.1 31.2 36.0 55.5 50.5 64.2 68.9 51.5 73.1 30.5 33.6 51.4 5.9 42.9 27.8 27.8 35.3 92.8 30.6 6.5 15.5 28.8 40.0 2.6 58.3 23.2 24.8 65.5 52.7 17.7 11.7 35.0 19.3 83.9 27.4 47.4 32.1 48.5 16.4 225.8 53.8 266.1 124.2 73.3 119.0 118.4 125.3 123.2 56.0 110.0 126.7 130.6 41.2 116.2 79.0 44.1 179.5 103.5 33.4 33.9 32.7 42.9 32.6 35.9 34.9 33.8 33.6 33.1 34.4 33.9 69.8 28.9 52.8 12.1 63.0 27.9 27.5 52.4 15.9 32.3 34.8 37.8 83.7 52.9 35.7 20.2 8.4 19.9 76.0 35.1 123.3 35.2 38.8 21.9 24.7 51.4 21.1 46.7 6.5 38.6 26.5 40.1 21.9 15.5 85.4 35.6 60.7 84.3 70.2 57.2 7.9 31.1 63.1 70.0 46.6 11.2 45.1 54.9 58.7 10.3 73.1 84.9 196.7 4.0 9.3 38.6 33.8 47.0 48.2 20.1 31.6 41.2 42.7 20.9 26.3 32.6 40.5 22.9 29.4 25.2 30.0 9.4 94.6 50.0 33.1 24.6 PPP1R21 "CCDC128, FLJ16566, KLRAQ1" ENSG00000162869 "Protein phosphatase 1 regulatory subunit 21" Q6ZMI0 2 48440598-48515391 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 99.6;Oligodendrocytes: 190.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036791, HPA036792" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "HPA036791: AB_10671713, HPA036792: AB_2675317" "unprognostic (1.25e-1)" "unprognostic (2.13e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (6.83e-4)" "unprognostic (1.57e-2)" "unprognostic (1.01e-1)" "unprognostic (2.78e-3)" "unprognostic (1.44e-2)" "unprognostic (7.46e-2)" "unprognostic (3.00e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.13e-1)" "prognostic favorable (4.59e-6)" "unprognostic (9.23e-2)" "unprognostic (1.93e-1)" "prognostic favorable (9.87e-4)" "unprognostic (6.60e-2)" 9.3 10.6 10.6 10.5 13.4 9.9 8.5 8.2 13.4 8.5 10.7 8.8 7.9 12.7 19.6 12.1 14.5 10.8 10.1 9.7 9.4 28.1 11.6 11.2 13.3 11.1 11.0 13.4 8.1 33.5 9.6 12.8 10.2 11.4 10.6 12.0 5.7 10.6 5.7 10.5 9.9 13.0 8.7 13.0 9.0 9.4 11.7 13.9 21.4 4.8 12.2 9.5 7.6 18.9 17.3 8.2 6.8 8.5 17.1 12.5 18.3 10.0 11.0 6.1 7.2 4.5 10.6 11.8 16.4 14.2 11.7 9.3 5.8 9.1 12.4 15.1 4.8 12.6 7.2 10.8 11.6 5.5 9.8 15.9 8.1 11.0 13.2 15.1 15.3 5.9 5.2 19.2 16.7 9.5 10.9 9.5 17.7 12.3 8.4 9.1 18.8 13.1 11.9 10.8 9.2 5.7 19.0 4.8 18.1 18.2 8.6 9.0 13.9 6.4 7.8 5.6 8.0 14.3 4.1 10.5 10.2 12.5 8.6 18.6 4.7 8.1 3.7 5.4 2.9 5.4 4.3 4.4 5.0 6.8 6.4 5.5 11.6 3.8 4.8 3.1 4.6 2.3 10.6 13.4 8.2 13.4 9.7 9.4 11.1 11.0 10.2 8.7 11.7 18.9 14.5 22.4 16.5 37.5 23.6 10.5 32.9 8.6 13.6 9.1 6.9 6.7 11.0 14.3 9.2 25.8 2.1 21.7 8.5 11.7 5.9 11.0 3.9 10.2 11.5 10.9 18.7 10.3 99.6 8.4 16.3 15.0 25.5 12.3 12.0 12.4 10.8 13.6 35.2 28.6 49.6 10.7 10.2 26.1 12.2 5.7 12.2 19.3 12.4 44.0 24.3 21.2 19.6 69.9 190.3 12.2 9.3 20.7 19.4 17.0 10.7 59.3 20.0 6.8 13.1 9.6 14.2 9.8 10.8 17.4 14.1 27.1 20.5 12.1 8.4 27.2 PPP1R3B "FLJ14005, GL, PPP1R4" ENSG00000173281 "Protein phosphatase 1 regulatory subunit 3B" Q86XI6 8 9136255-9151574 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.9;skeletal muscle: 95.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 69.9;Hepatocytes: 184.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "basophil: 53.6;eosinophil: 15.8;neutrophil: 50.4" "Lineage enriched" "Detected in all" 19 "granulocytes: 53.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 47.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA028731 Enhanced Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA028731: AB_10602120" "unprognostic (4.97e-3)" "unprognostic (1.45e-2)" "unprognostic (2.82e-1)" "unprognostic (3.46e-2)" "unprognostic (2.39e-1)" "unprognostic (5.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.68e-1)" "unprognostic (4.13e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (4.98e-2)" "prognostic unfavorable (4.08e-7)" "prognostic unfavorable (6.03e-5)" "unprognostic (3.33e-1)" "unprognostic (6.86e-2)" "unprognostic (1.21e-1)" 24.1 7.5 1.9 8.2 2.8 12.3 15.9 3.4 3.8 19.6 5.9 16.1 4.6 19.8 4.4 17.2 12.9 9.0 29.9 1.7 3.1 7.6 144.9 9.2 4.3 4.8 3.0 10.4 5.1 50.1 3.3 10.4 4.1 21.7 9.5 7.1 13.9 18.6 95.4 12.3 7.2 12.0 3.1 7.7 12.0 7.1 3.9 4.5 11.7 17.7 3.6 26.4 15.0 4.5 6.7 2.5 7.3 2.5 17.9 15.1 26.3 2.4 7.9 2.9 3.5 10.0 3.1 2.3 3.9 5.0 16.1 1.2 1.3 1.9 3.1 7.2 1.1 4.0 1.0 0.0 8.0 2.0 17.1 12.4 5.9 2.5 14.6 22.0 47.3 11.6 3.1 5.6 1.1 4.1 11.2 3.8 10.6 15.2 2.2 4.5 9.2 4.0 28.6 26.9 0.0 13.6 4.4 0.1 18.6 11.6 3.4 4.1 32.9 8.5 2.9 1.7 3.1 3.1 7.5 0.0 14.8 6.2 2.6 53.6 1.6 15.8 2.2 1.1 1.8 1.6 2.0 1.2 0.9 1.2 2.7 1.5 50.4 2.2 0.7 1.8 1.5 1.6 1.9 2.8 3.4 3.8 1.7 3.1 4.8 3.0 4.1 3.1 3.9 4.5 16.7 12.8 34.5 0.7 5.5 10.7 18.8 7.2 3.4 3.7 19.4 12.7 69.9 24.3 21.8 9.2 6.2 12.9 7.6 26.7 3.9 8.8 20.3 29.5 21.9 21.0 0.0 0.8 0.8 12.7 38.3 12.7 9.7 51.7 33.6 10.4 31.1 184.7 6.9 6.7 0.4 11.5 8.2 9.8 27.9 5.2 9.6 15.6 5.4 3.7 3.1 3.9 4.1 3.5 1.4 18.4 7.5 18.0 4.5 8.0 7.4 6.8 30.8 13.0 13.1 10.9 17.9 1.7 5.7 0.6 12.1 18.3 10.8 9.4 5.5 2.2 PPP2R2A "B55A, B55alpha, PR52A, PR55A, PR55alpha" ENSG00000221914 "Protein phosphatase 2 regulatory subunit Balpha" P63151 8 26291508-26372680 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, CAB079289" Approved Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB079289: AB_659890, HPA042122: AB_2677859, HPA042770: AB_2678155" "unprognostic (1.17e-1)" "unprognostic (2.68e-2)" "unprognostic (4.29e-3)" "unprognostic (5.34e-2)" "unprognostic (3.44e-2)" "unprognostic (2.11e-2)" "unprognostic (4.64e-3)" "unprognostic (3.65e-1)" "unprognostic (2.48e-1)" "unprognostic (3.87e-2)" "unprognostic (2.71e-2)" "unprognostic (8.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (2.90e-1)" "unprognostic (3.44e-2)" "unprognostic (1.16e-1)" 32.1 16.1 8.9 12.7 13.1 4.7 30.4 9.1 14.3 33.1 6.4 19.1 21.7 22.3 8.5 59.6 24.6 14.1 26.7 9.5 10.2 18.0 28.3 25.8 16.0 9.4 9.7 24.7 14.7 14.0 13.5 38.2 9.2 19.5 15.2 10.5 27.0 15.9 53.4 38.9 19.4 18.3 10.2 17.9 17.7 18.1 8.8 16.0 19.4 23.6 25.7 24.2 37.0 13.6 42.1 33.5 52.5 32.2 28.3 43.6 54.2 74.5 49.4 63.1 65.2 48.9 24.2 54.5 19.1 28.9 31.5 51.2 56.9 50.1 78.0 23.8 24.4 43.8 36.6 23.0 42.0 25.2 19.1 29.3 62.4 39.4 52.0 31.7 96.1 27.5 64.1 37.1 51.7 26.0 54.4 17.6 62.5 73.6 20.5 36.1 35.1 41.8 31.0 74.8 21.0 27.7 30.3 27.9 41.0 37.2 26.9 13.7 45.8 28.5 46.0 31.4 47.0 18.6 32.4 80.9 35.1 39.7 52.2 0.6 0.4 1.6 0.4 0.9 0.7 1.3 1.1 1.0 1.1 1.1 0.6 0.9 1.0 0.9 0.9 0.7 1.8 0.7 8.9 13.1 9.1 14.3 9.5 10.2 9.4 9.7 9.2 10.2 8.8 13.6 63.4 73.7 67.8 42.1 59.2 136.6 215.9 81.6 72.8 53.0 65.6 52.5 36.9 27.1 98.8 14.7 47.9 76.6 70.2 57.5 49.0 45.5 47.9 100.5 51.6 82.3 76.9 53.5 95.1 32.2 65.3 65.5 57.6 98.4 55.2 61.0 55.3 34.6 36.6 37.0 49.9 51.2 61.1 32.0 66.1 128.8 46.9 47.6 60.5 72.1 48.1 51.6 35.0 122.6 250.6 61.0 50.1 73.4 53.5 140.0 44.4 43.9 111.2 40.8 52.6 56.1 76.7 44.6 57.2 102.3 142.9 66.9 66.5 59.9 50.6 232.8 PPP4R1 PP4R1 ENSG00000154845 "Protein phosphatase 4 regulatory subunit 1" Q8TF05 18 9546791-9615240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040905, HPA041089" Uncertain Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA040905: AB_10794869, HPA041089: AB_10805836" "unprognostic (1.76e-1)" "unprognostic (5.33e-2)" "unprognostic (1.40e-2)" "unprognostic (5.14e-2)" "unprognostic (3.74e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-3)" "unprognostic (9.36e-2)" "unprognostic (1.16e-2)" "unprognostic (4.00e-3)" "unprognostic (3.13e-3)" "unprognostic (4.15e-1)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (2.76e-1)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" 20.7 16.2 16.7 16.8 19.1 32.0 18.8 18.7 17.8 27.2 19.1 24.7 23.2 20.8 17.1 70.7 21.1 20.7 20.7 15.6 17.4 19.6 15.3 34.6 13.0 17.7 17.2 17.0 19.9 23.5 11.7 29.0 17.7 16.6 19.7 13.3 23.3 16.9 16.2 26.1 26.1 23.3 16.9 18.4 24.4 35.7 17.0 19.9 18.7 17.4 24.9 40.7 35.7 20.6 70.3 48.5 115.0 31.6 22.3 33.7 58.3 66.9 44.7 64.9 62.3 44.1 39.6 34.0 47.6 66.1 55.0 29.4 54.0 99.4 87.0 39.8 21.8 32.2 35.0 32.0 34.7 83.0 46.7 30.3 62.8 56.1 52.9 48.5 75.3 22.6 47.5 29.8 70.9 34.5 58.1 31.7 46.1 97.5 30.3 71.5 69.2 21.4 54.6 96.5 33.6 39.5 79.3 35.3 26.4 73.3 19.3 31.5 81.3 113.6 70.2 59.3 83.5 26.5 39.7 60.7 42.5 34.0 52.5 14.6 6.1 10.9 3.9 4.7 5.0 3.8 4.3 3.9 7.0 1.8 1.4 3.2 36.1 4.1 4.7 2.9 4.6 3.5 16.7 19.1 18.7 17.8 15.6 17.4 17.7 17.2 17.7 16.9 17.0 20.6 26.4 99.3 76.1 35.9 11.9 40.4 26.5 30.8 42.7 19.6 20.7 14.7 21.4 7.2 55.4 22.0 10.4 27.0 12.0 31.2 5.9 23.8 77.3 48.1 26.7 29.5 17.4 15.6 43.0 34.9 15.9 19.3 45.3 54.0 3.8 27.0 26.0 12.2 16.8 33.7 54.9 16.4 8.2 19.6 16.7 57.2 17.4 20.7 14.2 34.7 20.5 10.6 13.4 61.9 66.5 49.8 16.2 11.7 10.8 21.0 23.7 10.0 58.9 19.3 13.1 16.5 22.1 20.4 12.3 52.0 42.5 23.0 12.9 9.2 13.6 68.4 PRKACB PKACb ENSG00000142875 "Protein kinase cAMP-activated catalytic subunit beta" P22694 1 84078062-84238498 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 334.4;Inhibitory neurons: 348.8;Oligodendrocyte precursor cells: 302.6;Oligodendrocytes: 499.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010363, HPA029754, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA 130000 "Cluster 48: NK-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Cytokinetic bridge" "CAB010363: AB_2170182, HPA029754: AB_10601491, HPA071185: AB_2686356" "unprognostic (9.38e-2)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.49e-4)" "unprognostic (1.28e-1)" "unprognostic (3.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "prognostic favorable (1.89e-6)" "unprognostic (1.22e-1)" "unprognostic (3.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.48e-1)" 16.5 47.7 79.4 26.1 101.6 16.0 17.7 70.0 113.3 19.8 0.0 55.9 10.8 19.2 38.8 17.8 10.0 26.2 23.8 100.7 107.5 23.8 20.8 15.8 41.8 53.5 44.4 17.8 27.8 23.5 24.7 11.5 65.4 30.6 51.7 71.6 83.7 27.3 4.9 4.1 12.7 28.8 59.9 36.0 34.1 8.1 91.0 63.5 25.2 13.5 36.8 27.6 7.7 110.0 8.6 16.9 26.4 31.8 29.9 26.1 12.3 41.7 31.4 20.8 19.4 0.4 7.5 45.1 28.0 32.8 38.0 5.8 12.6 13.6 22.0 44.1 6.8 99.3 21.3 3.2 29.4 39.8 2.2 15.6 6.0 20.2 11.2 30.2 97.2 16.7 3.2 25.2 34.3 1.6 51.8 21.0 26.1 0.1 11.8 39.6 41.2 27.3 50.5 30.2 8.6 33.4 23.0 8.8 25.6 19.7 8.1 8.2 86.8 28.7 22.4 29.4 31.9 18.6 24.2 45.3 13.7 41.5 36.5 56.3 7.5 16.4 59.3 10.2 47.7 35.2 43.4 52.9 19.4 28.4 65.0 69.5 3.8 73.1 16.2 11.1 44.2 66.8 79.4 101.6 70.0 113.3 100.7 107.5 53.5 44.4 65.4 59.9 91.0 110.0 9.5 0.0 1.5 118.8 56.6 5.1 7.2 3.5 11.4 44.9 11.5 9.1 44.4 21.5 5.2 14.7 35.5 1.9 103.0 115.5 33.2 6.2 2.9 11.4 27.0 13.4 21.7 52.3 334.4 11.9 1.2 17.0 16.3 14.0 58.9 15.2 28.5 17.0 27.1 47.1 348.8 58.1 4.1 62.3 24.4 3.6 14.9 51.6 16.0 95.5 14.6 35.6 96.8 302.6 499.0 20.6 42.2 21.8 53.9 10.0 4.5 25.6 6.3 34.4 13.1 14.1 20.3 13.9 8.0 8.1 2.8 0.7 87.6 11.4 51.1 9.1 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.5" "Cell type enhanced" "Detected in many" "Early spermatids: 206.5;Excitatory neurons: 394.4;Inhibitory neurons: 531.9;Late spermatids: 456.4;Oligodendrocyte precursor cells: 147.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.5;basal ganglia: 20.0;cerebral cortex: 34.5;hippocampal formation: 33.1;white matter: 17.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "REH: 27.0;TIME: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: AB_2678959" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favorable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favorable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 4.4 5.6 18.5 3.7 20.0 8.0 4.2 5.5 34.5 4.6 0.0 5.7 2.6 4.4 2.3 4.1 5.7 3.0 6.2 33.1 0.0 10.0 12.5 20.1 5.7 6.0 0.2 2.8 3.3 9.4 5.2 8.3 4.4 2.9 3.3 15.4 2.7 3.0 7.6 2.7 3.5 4.1 0.0 3.9 4.1 7.6 1.1 3.1 4.9 5.3 4.2 4.9 3.4 17.1 7.7 2.7 3.8 3.8 5.8 6.7 3.1 4.9 9.5 4.3 4.5 0.7 7.0 11.3 4.8 5.5 6.1 1.8 2.5 2.8 6.1 6.9 4.4 0.1 1.8 1.5 6.5 0.9 3.8 5.8 3.0 6.5 4.7 3.6 16.0 2.4 1.6 2.6 5.0 3.8 3.8 0.5 1.3 4.2 1.4 27.0 18.3 12.4 3.9 5.1 2.6 5.7 2.4 7.6 17.1 1.4 6.1 2.6 26.8 8.2 8.5 6.1 5.1 0.0 0.0 9.3 6.7 6.3 8.4 0.0 0.5 0.7 0.3 0.1 0.4 1.5 0.2 0.2 0.8 1.8 0.5 0.1 0.1 0.4 0.6 0.3 0.0 0.3 18.5 20.0 5.5 34.5 33.1 0.0 6.0 0.2 4.4 0.0 1.1 17.1 12.6 6.4 9.2 90.4 20.7 5.0 8.4 5.0 9.1 55.3 6.4 5.7 11.9 8.6 17.2 11.0 14.6 0.5 9.3 6.1 3.9 3.7 206.5 6.8 7.0 13.8 7.7 0.4 394.4 3.8 7.2 8.7 11.2 6.9 7.0 2.9 13.2 12.5 2.8 11.8 531.9 5.8 0.0 19.0 10.7 456.4 5.3 11.5 14.2 70.3 9.4 6.5 1.0 147.8 96.0 3.6 2.9 6.0 4.2 5.3 4.1 30.2 19.3 7.6 13.1 2.9 6.4 2.8 2.3 9.0 4.8 2.9 6.8 1.2 6.2 8.8 PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 128.4;Microglial cells: 267.9;NK-cells: 229.6;T-cells: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.5;MAIT T-cell: 91.3;memory CD4 T-cell: 88.0;memory CD8 T-cell: 137.0;naive CD4 T-cell: 106.9;naive CD8 T-cell: 105.5;NK-cell: 117.1;T-reg: 79.8" "Group enriched" "Detected in all" 14 "NK-cells: 117.1;T-cells: 137.0" "Cell line enhanced" "Detected in many" "BEWO: 81.8;HUVEC TERT2: 108.7;MOLT-4: 75.8;RT4: 46.4;TIME: 72.0" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" 26.6 7.8 21.1 21.9 30.2 24.2 21.9 12.4 15.7 20.6 9.5 8.9 9.5 14.5 10.9 30.0 13.6 19.7 19.2 13.2 13.9 14.5 10.3 35.3 55.2 19.3 21.7 5.9 8.4 14.2 15.0 32.5 19.4 15.8 8.8 3.1 28.3 11.4 14.2 23.7 16.6 18.1 18.6 38.5 9.6 7.5 29.9 65.8 21.1 18.1 38.5 25.3 21.7 15.5 18.1 6.3 0.8 4.9 2.8 0.6 81.8 0.3 1.5 0.8 0.8 1.9 10.5 0.3 12.4 0.1 1.6 12.3 0.6 13.5 1.4 2.2 7.9 0.1 2.0 0.7 1.2 0.0 2.4 2.2 13.8 0.7 9.4 1.2 108.7 35.4 0.2 0.4 6.2 32.7 75.8 0.7 1.4 12.9 8.4 6.3 3.2 0.2 0.2 46.4 3.2 5.1 2.1 16.2 10.2 14.5 15.9 1.4 72.0 2.1 14.0 2.1 0.9 1.4 0.2 0.6 3.1 1.1 3.6 0.8 3.0 2.4 116.5 1.9 91.3 2.2 88.0 137.0 9.2 1.4 106.9 105.5 5.9 117.1 1.1 3.0 79.8 84.0 21.1 30.2 12.4 15.7 13.2 13.9 19.3 21.7 19.4 18.6 29.9 15.5 59.7 6.4 11.4 2.0 6.6 18.7 16.4 8.3 15.9 0.4 15.0 9.3 9.0 10.0 15.5 0.0 0.0 27.6 128.4 0.6 3.9 6.0 32.6 10.3 2.1 70.8 11.9 18.1 1.7 6.8 21.2 5.0 7.1 20.9 1.3 15.4 68.9 2.0 6.0 0.0 3.1 2.7 2.0 14.4 6.9 6.0 1.8 15.4 16.0 267.9 8.9 7.0 229.6 4.5 1.8 5.4 4.3 6.8 26.6 14.7 4.6 1.2 9.2 0.5 0.0 4.4 5.2 0.1 2.4 18.1 26.7 48.3 130.5 1.6 1.3 26.0 PRM3 ENSG00000178257 "Protamine 3" Q9NNZ6 16 11273199-11273629 "Predicted intracellular proteins" "Differentiation, DNA condensation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 88.9" "Cell type enriched" "Detected in some" 4 "Late spermatids: 3440.3" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "TIME: 3.6" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" 0.0 0.0 0.4 0.0 0.6 2.6 0.0 2.4 1.2 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.2 0.6 0.0 0.0 0.1 0.2 0.0 88.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 2.4 1.2 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 854.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3440.3 12.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.9 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PROCR "CCD41, CD201, EPCR" ENSG00000101000 "Protein C receptor" Q9UNN8 20 35172072-35216240 "Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 126.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 114.2;Fibroblasts: 83.4;granulocytes: 63.1;Hepatic stellate cells: 74.6;Sertoli cells: 170.9;Syncytiotrophoblasts: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 385.0;HUVEC TERT2: 611.1;TIME: 365.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 8.9" HPA039461 Enhanced NA NA 980000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "HPA039461: AB_10673359" "unprognostic (1.51e-1)" "unprognostic (1.03e-1)" "unprognostic (4.12e-2)" "unprognostic (1.68e-1)" "unprognostic (2.64e-1)" "unprognostic (4.69e-2)" "unprognostic (4.69e-2)" "unprognostic (1.84e-1)" "unprognostic (1.52e-1)" "unprognostic (4.76e-2)" "unprognostic (5.22e-2)" "unprognostic (4.27e-1)" "prognostic unfavorable (7.62e-6)" "unprognostic (3.37e-2)" "unprognostic (2.29e-1)" "unprognostic (1.05e-1)" "unprognostic (2.19e-2)" 126.8 23.1 6.8 19.6 7.3 8.6 53.9 12.0 7.7 31.2 14.6 25.2 16.3 36.2 13.4 12.0 42.9 21.2 43.5 7.0 6.8 15.6 6.8 19.8 10.0 8.9 7.3 18.0 12.6 6.1 8.6 31.3 8.8 19.5 21.4 1.8 8.7 17.3 10.1 25.2 21.4 28.4 7.5 27.5 23.2 5.0 8.9 3.0 26.0 10.3 4.0 34.2 28.4 10.1 15.2 88.9 0.2 9.2 93.6 76.1 20.2 20.8 90.4 33.7 65.2 115.2 76.7 2.9 63.3 21.0 93.6 48.5 20.2 131.8 27.8 0.7 27.5 33.2 19.8 4.7 22.8 1.3 385.0 65.1 48.8 159.0 131.1 49.2 611.1 1.1 11.8 4.2 35.3 5.0 1.1 1.6 12.2 18.8 90.4 0.6 16.7 0.4 58.3 5.8 2.7 1.2 11.3 23.9 18.8 11.0 8.1 5.0 365.5 86.0 43.2 32.8 35.4 0.3 1.1 0.9 99.1 33.5 18.6 5.0 1.5 0.8 8.2 1.8 14.8 0.9 2.5 5.2 7.8 1.3 0.6 5.9 4.0 3.3 1.3 1.3 2.2 2.2 6.8 7.3 12.0 7.7 7.0 6.8 8.9 7.3 8.8 7.5 8.9 10.1 19.9 0.0 12.6 2.3 0.5 13.9 18.5 10.1 10.2 0.5 1.1 4.4 2.4 5.7 4.9 5.5 0.0 12.1 2.0 0.5 1.9 32.2 1.6 1.0 24.0 58.8 6.0 2.7 3.6 16.4 114.2 83.4 1.5 0.9 63.1 15.9 74.6 1.9 21.9 1.7 2.5 0.7 0.0 1.6 8.8 1.0 15.5 13.5 3.6 9.4 2.2 0.3 7.2 0.5 5.6 15.6 0.5 2.6 0.6 9.7 9.8 6.3 1.8 0.6 170.9 4.3 45.9 20.4 19.7 2.8 8.4 69.0 4.4 4.2 2.0 11.9 PRSS23 "SIG13, SPUVE" ENSG00000150687 "Serine protease 23" O95084 11 86791059-86952910 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 249.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.1;Endothelial cells: 502.1;Granulosa cells: 347.3;Hepatic stellate cells: 591.8;Theca cells: 445.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 104.6" "Group enriched" "Detected in many" 25 "NK-cells: 34.2;T-cells: 104.6" "Cell line enhanced" "Detected in many" "GAMG: 1093.7;hTERT-RPE1: 1296.9;TIME: 1138.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030591 Uncertain "Secreted to blood" NA NA 440000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA030591: AB_10602067" "unprognostic (2.68e-2)" "unprognostic (1.20e-2)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (2.40e-3)" "prognostic unfavorable (2.12e-4)" "unprognostic (1.89e-2)" "unprognostic (4.30e-2)" "unprognostic (2.08e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (5.56e-4)" "unprognostic (5.35e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.13e-3)" "unprognostic (9.44e-2)" "unprognostic (1.99e-3)" "unprognostic (8.01e-2)" 55.0 21.4 7.8 35.3 7.8 2.1 43.2 7.1 8.7 249.1 12.9 103.6 19.2 103.4 13.4 22.1 24.9 83.8 28.3 7.9 8.0 42.4 15.0 63.3 21.8 14.0 13.9 26.8 29.8 36.0 16.4 61.7 8.8 61.3 50.3 2.7 52.4 128.2 79.6 19.4 29.0 115.5 7.1 18.0 54.2 31.8 14.1 17.5 40.9 18.7 10.2 99.6 79.1 7.4 62.7 153.3 161.1 1.0 70.4 172.3 0.7 269.0 244.4 293.2 232.6 368.1 484.7 0.2 208.2 414.7 1093.7 126.2 2.6 205.0 70.9 0.7 13.0 21.1 74.7 1.4 36.3 0.1 0.9 137.4 26.8 143.2 162.1 1296.9 604.8 0.9 1.3 0.3 223.4 87.7 0.2 0.3 9.8 211.7 16.8 0.0 0.0 0.7 111.5 82.3 1.5 1.0 59.9 4.5 18.7 397.6 6.0 0.6 1138.2 174.0 2.3 351.7 154.5 1.3 1.3 0.8 124.2 0.5 176.3 0.2 0.2 0.1 104.6 0.1 0.2 0.2 17.8 60.0 0.2 0.0 4.7 50.4 1.6 34.2 2.7 0.2 0.0 39.9 7.8 7.8 7.1 8.7 7.9 8.0 14.0 13.9 8.8 7.1 14.1 7.4 95.8 28.9 14.5 14.0 3.2 15.4 96.2 367.1 2.8 1.6 44.7 78.0 4.3 37.1 231.3 53.3 2.1 18.4 53.4 154.8 7.9 162.6 3.1 10.3 130.3 502.1 13.8 20.4 26.3 83.5 15.7 117.1 22.4 7.0 2.5 347.3 591.8 5.2 5.0 0.0 16.5 30.6 85.5 36.6 18.2 6.6 14.3 5.4 72.9 39.4 1.5 0.8 180.2 11.6 2.3 257.7 80.1 7.5 5.8 100.1 5.2 5.7 90.1 0.9 39.5 14.4 105.9 3.0 7.3 1.7 9.8 4.5 24.0 445.1 11.1 60.2 PSMD10 p28 ENSG00000101843 "Proteasome 26S subunit, non-ATPase 10" O75832 X 108084207-108091549 "Predicted intracellular proteins" Apoptosis Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002920, CAB010434" Approved Supported "Intermediate filaments,Cytosol" NA NA 250000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" Cytosol "Intermediate filaments" "CAB010434: AB_640866, HPA002920: AB_1079708" "unprognostic (1.59e-3)" "unprognostic (4.12e-3)" "unprognostic (3.83e-1)" "unprognostic (3.00e-1)" "unprognostic (4.65e-2)" "unprognostic (1.50e-2)" "unprognostic (3.85e-3)" "unprognostic (2.35e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-2)" "unprognostic (4.95e-2)" "unprognostic (7.37e-3)" "unprognostic (1.64e-2)" "unprognostic (1.42e-2)" "unprognostic (2.09e-1)" "unprognostic (5.07e-2)" "unprognostic (1.09e-1)" 28.2 38.6 49.4 26.2 52.3 28.7 35.1 54.5 68.3 34.3 47.4 32.7 25.3 36.4 48.3 34.5 44.9 25.8 26.0 49.9 58.9 34.6 33.4 28.6 34.8 55.4 58.6 31.7 18.6 41.4 33.1 40.4 61.4 31.6 33.2 44.6 26.2 30.4 24.8 26.8 27.0 36.2 56.4 27.1 27.8 27.5 57.5 41.9 38.1 23.9 39.1 33.4 27.7 59.4 101.3 100.5 68.9 62.6 102.6 77.3 61.8 81.6 69.2 73.9 64.0 60.7 64.4 86.0 119.7 80.2 107.6 54.0 109.8 80.3 113.4 91.3 94.8 50.5 91.0 78.2 51.8 79.2 54.8 58.2 85.9 67.2 82.2 73.2 186.4 83.2 99.9 114.3 94.0 133.0 75.3 70.9 124.1 96.9 138.3 74.2 97.5 92.7 80.7 64.8 44.2 42.1 124.8 52.4 86.0 87.4 56.5 66.9 130.5 58.1 33.1 98.3 61.4 88.5 128.5 90.5 80.4 109.2 69.7 83.6 46.8 72.3 45.9 58.1 49.0 47.9 45.8 49.2 52.2 48.0 45.6 51.4 22.0 58.3 71.4 53.0 57.8 69.9 49.4 52.3 54.5 68.3 49.9 58.9 55.4 58.6 61.4 56.4 57.5 59.4 14.2 19.2 19.8 3.3 23.4 22.6 25.9 31.8 23.9 15.1 20.4 20.6 11.2 8.6 35.4 11.0 2.1 28.3 12.8 16.5 31.3 19.9 4.1 38.3 26.9 22.8 14.4 35.7 3.4 18.7 35.3 22.6 11.7 21.6 34.1 17.9 22.1 25.6 31.3 13.5 4.5 16.8 16.2 29.5 19.0 4.4 25.7 20.2 17.8 0.0 26.1 18.3 20.6 5.5 9.6 24.5 14.1 21.1 34.7 26.6 14.9 34.8 69.9 7.7 0.0 13.8 32.1 46.2 40.3 32.4 29.1 25.0 20.2 24.6 19.2 33.7 PTGER4 EP4 ENSG00000171522 "Prostaglandin E receptor 4" P35408 5 40679915-40693735 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 85.7;pancreas: 54.2" "Cell type enhanced" "Detected in many" "dendritic cells: 134.8;Langerhans cells: 130.7;Macrophages: 90.2;T-cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 43.2;HUVEC TERT2: 28.7;LHCN-M2: 27.6;RT4: 43.1;THP-1: 27.4;TIME: 54.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011226, HPA012756" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "HPA011226: AB_1855885, HPA012756: AB_1855884" "unprognostic (1.79e-2)" "unprognostic (6.53e-3)" "unprognostic (9.43e-3)" "unprognostic (6.77e-3)" "unprognostic (1.44e-1)" "unprognostic (7.16e-2)" "unprognostic (7.28e-3)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "unprognostic (3.61e-2)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.48e-4)" 11.7 9.7 0.7 15.1 0.5 85.7 6.3 0.9 1.0 3.1 1.1 20.3 20.6 2.7 1.2 5.6 12.1 11.2 6.4 0.8 0.8 8.5 4.1 18.3 15.4 1.8 2.4 1.2 54.2 1.0 1.1 3.0 1.7 3.0 17.0 0.1 3.5 2.5 3.9 3.8 24.8 5.9 1.7 12.5 19.7 2.9 1.0 19.4 2.8 6.8 9.3 11.6 2.4 3.3 3.7 0.8 0.0 0.1 16.7 19.7 0.1 0.3 1.4 1.0 0.7 0.0 1.1 0.4 0.3 0.0 17.5 2.8 0.2 6.7 1.7 43.2 0.8 0.0 1.5 0.0 15.1 15.2 3.0 2.1 1.0 10.2 4.1 2.3 28.7 14.7 0.0 10.2 27.6 0.0 16.3 7.0 0.1 0.7 6.5 10.7 2.7 1.4 3.9 43.1 0.0 0.0 0.6 1.3 0.1 0.6 6.6 27.4 54.0 5.5 0.0 0.1 1.3 0.1 0.3 2.0 2.4 11.3 1.5 5.3 7.1 14.6 15.8 19.0 9.0 1.8 9.5 9.9 8.1 1.6 5.7 8.1 12.8 3.8 24.7 1.1 8.4 7.3 0.7 0.5 0.9 1.0 0.8 0.8 1.8 2.4 1.7 1.7 1.0 3.3 44.5 12.8 9.0 1.3 46.4 61.2 5.8 16.2 22.8 0.0 9.4 9.1 3.9 0.0 10.2 7.3 0.0 0.2 134.8 45.7 0.0 0.9 3.7 1.6 1.4 18.0 13.1 2.5 2.8 7.7 0.9 30.0 29.6 2.2 10.1 4.6 3.6 0.8 29.5 0.0 3.4 53.8 4.1 49.7 130.7 1.8 0.9 90.2 19.6 3.7 48.8 0.1 57.7 1.5 7.1 2.9 28.1 0.4 38.6 6.7 16.3 0.1 13.0 0.3 0.0 39.1 11.8 7.1 1.0 17.5 30.4 0.3 214.9 0.1 31.4 1.4 PTGFRN "CD315, CD9P-1, EWI-F, FLJ11001, FPRP, KIAA1436, SMAP-6" ENSG00000134247 "Prostaglandin F2 receptor inhibitor" Q9P2B2 1 116909916-116990353 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 66.2;Cardiomyocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-87 MG: 146.8;WM-115: 111.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017074 Approved NA NA 340000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA017074: AB_1855888" "unprognostic (1.18e-1)" "unprognostic (2.11e-3)" "unprognostic (3.03e-1)" "unprognostic (8.58e-2)" "unprognostic (3.20e-1)" "unprognostic (2.91e-2)" "unprognostic (1.48e-3)" "unprognostic (3.39e-2)" "unprognostic (1.76e-2)" "unprognostic (7.28e-2)" "unprognostic (2.77e-2)" "unprognostic (5.28e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "unprognostic (4.15e-2)" 11.6 21.1 3.2 10.1 3.5 0.0 10.6 3.3 4.8 14.9 8.3 40.6 11.3 31.2 10.6 21.2 23.9 17.2 48.8 3.3 2.6 4.0 6.6 6.6 2.5 2.8 4.5 15.9 13.3 6.3 2.9 5.0 2.2 18.0 21.7 1.4 18.5 23.6 2.9 17.8 14.0 46.6 4.6 3.1 10.5 5.3 4.1 5.3 6.9 3.9 6.2 20.1 15.1 3.2 40.0 10.3 18.4 42.8 3.2 8.3 2.6 2.8 4.4 15.4 5.8 7.2 8.7 0.0 35.7 10.6 12.7 69.7 41.4 74.4 9.7 0.4 25.1 2.9 24.0 11.1 1.1 0.1 3.9 37.3 66.0 2.0 36.4 21.9 30.0 4.2 16.5 0.2 23.5 50.9 0.0 5.5 21.5 3.3 0.1 0.0 100.6 0.2 51.3 32.4 9.0 20.8 80.0 55.9 22.9 32.1 48.8 12.3 77.6 22.4 33.2 37.2 25.1 0.0 0.1 0.1 146.8 0.0 111.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 3.5 3.3 4.8 3.3 2.6 2.8 4.5 2.2 4.6 4.1 3.2 2.3 3.2 5.9 15.0 0.5 66.2 13.4 25.6 22.2 6.5 10.9 11.9 79.4 10.0 12.2 3.7 0.0 0.8 0.3 20.6 1.9 31.2 4.8 10.2 19.3 12.1 13.9 0.0 13.6 31.8 5.5 32.0 10.7 16.9 0.0 22.1 3.9 11.1 4.4 0.0 7.4 18.2 14.2 8.8 9.7 6.3 19.3 4.7 8.8 3.7 3.1 1.2 0.0 31.2 0.9 27.9 11.1 30.1 0.0 15.1 15.8 1.2 13.6 0.2 19.7 48.5 12.5 0.8 5.2 20.3 45.3 0.8 1.4 28.3 26.3 17.4 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 295.2;Excitatory neurons: 584.9;Oligodendrocyte precursor cells: 353.9;Oligodendrocytes: 791.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" NA Yes 25000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavorable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 51.0 40.4 83.8 19.5 115.1 6.7 42.1 62.4 99.9 40.3 51.0 37.2 25.8 37.3 49.7 25.6 34.0 32.1 36.9 84.5 77.3 42.6 30.1 39.4 25.3 79.1 87.6 33.7 32.1 53.1 21.3 74.2 81.0 34.0 35.3 35.5 39.9 41.6 38.7 29.6 29.5 37.6 67.6 22.8 32.8 38.9 86.7 11.9 38.7 39.4 25.8 43.9 34.0 154.5 52.6 81.9 111.0 40.3 45.8 48.8 71.6 50.8 70.0 46.3 45.3 35.9 42.1 31.7 111.7 65.3 65.0 60.3 66.1 116.0 69.6 0.3 30.8 70.1 44.3 50.0 62.5 0.1 31.8 33.4 55.8 58.0 81.0 121.5 139.0 44.0 72.0 0.8 62.9 91.0 0.9 0.7 43.2 113.2 90.3 46.8 60.9 1.5 97.7 117.3 43.9 54.8 79.0 25.0 52.0 97.2 59.2 1.2 84.9 45.2 85.5 54.0 58.1 0.0 0.6 3.4 58.7 0.6 62.9 1.6 3.3 0.0 0.2 1.4 0.0 5.3 0.6 0.0 4.5 6.3 4.4 1.6 1.3 4.7 0.8 6.1 0.2 3.9 83.8 115.1 62.4 99.9 84.5 77.3 79.1 87.6 81.0 67.6 86.7 154.5 71.3 32.1 33.1 295.2 20.6 33.3 70.1 36.3 64.9 55.2 29.3 23.5 29.6 32.9 32.1 55.2 60.5 37.0 8.0 23.1 23.5 27.2 68.4 29.3 43.3 54.3 25.8 8.4 584.9 23.3 53.7 37.2 37.8 46.5 9.5 84.7 37.5 15.7 8.1 67.3 263.6 23.0 30.5 15.2 15.9 38.8 23.9 19.4 24.9 159.3 3.9 40.9 0.0 353.9 791.4 43.1 23.5 21.8 1.7 82.4 29.3 25.6 33.7 55.0 98.6 32.7 128.4 88.9 65.5 42.8 25.9 33.2 3.4 67.0 24.1 87.3 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRE PTPE ENSG00000132334 "Protein tyrosine phosphatase receptor type E" P23469 10 127907103-128085855 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 46.9" "Cell type enhanced" "Detected in many" "dendritic cells: 256.6;Inhibitory neurons: 191.6;Langerhans cells: 307.9;Macrophages: 276.3;Oligodendrocyte precursor cells: 247.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 634.6;plasmacytoid DC: 475.9" "Group enriched" "Detected in all" 12 "dendritic cells: 475.9;granulocytes: 634.6;monocytes: 175.4" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 38.6;HUVEC TERT2: 41.6;NB-4: 32.5;TIME: 79.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015870, HPA021872" Supported Approved "Intermediate filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Intermediate filaments" "HPA015870: AB_1855759, HPA021872: AB_1855760" "unprognostic (5.23e-2)" "unprognostic (1.37e-1)" "unprognostic (1.99e-1)" "unprognostic (7.11e-2)" "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (6.50e-2)" "unprognostic (4.49e-2)" "unprognostic (2.11e-1)" "unprognostic (2.56e-2)" "unprognostic (8.71e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (4.08e-5)" "unprognostic (1.52e-1)" "unprognostic (6.71e-3)" "unprognostic (2.49e-2)" "unprognostic (5.59e-2)" 13.6 16.7 13.9 25.3 8.9 46.9 6.7 5.7 13.9 3.9 7.7 9.2 9.5 3.5 2.6 7.9 4.9 10.3 10.6 14.2 11.1 4.3 4.4 16.0 16.4 11.6 9.0 1.6 2.7 2.7 5.0 7.8 10.7 3.4 9.3 1.0 5.8 2.4 1.3 4.7 12.9 7.4 10.8 20.6 7.4 2.6 10.7 8.6 5.5 3.1 9.8 12.7 4.4 14.2 4.3 0.9 0.5 0.0 2.5 0.4 7.5 0.1 0.0 1.6 3.6 1.7 25.1 3.3 2.6 2.1 5.2 2.3 2.1 12.2 0.7 4.0 1.9 0.4 1.4 0.0 4.1 16.2 11.6 0.8 6.9 6.1 12.1 38.6 41.6 10.3 0.0 1.9 2.6 4.0 4.9 32.5 0.2 4.6 1.5 19.1 2.6 6.4 6.8 18.0 0.0 2.5 7.4 1.3 0.3 1.8 0.6 20.1 79.5 1.7 1.8 7.8 8.9 0.9 1.3 4.6 11.3 12.5 0.0 174.3 175.4 147.2 36.6 64.5 22.3 7.7 16.5 25.1 97.9 8.3 11.5 19.6 634.6 31.6 54.9 475.9 26.7 43.3 13.9 8.9 5.7 13.9 14.2 11.1 11.6 9.0 10.7 10.8 10.7 14.2 25.0 83.3 57.2 22.5 26.2 59.5 54.3 42.4 15.9 5.2 14.2 23.6 20.3 8.6 23.7 3.7 0.0 43.2 256.6 15.7 0.0 3.7 2.1 3.6 10.6 78.0 6.7 10.3 112.7 4.4 67.4 17.5 10.7 7.7 31.6 3.7 47.5 2.3 57.5 0.0 191.6 15.8 18.3 166.7 307.9 2.5 0.6 276.3 24.9 165.8 139.5 0.0 150.4 247.3 93.4 49.2 13.3 0.4 38.5 21.3 13.9 2.2 7.8 0.9 0.0 86.0 12.8 0.5 1.9 20.4 64.6 17.0 59.3 9.2 11.7 40.3 PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase receptor type K" Q15262 6 127968785-128520616 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 889.9;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 1278.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.6;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 13000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: AB_2682359, HPA054822: AB_2682614" "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favorable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" 10.7 4.2 13.4 9.7 20.6 0.2 25.6 16.7 18.6 13.5 8.6 27.3 32.8 12.1 8.2 9.7 14.9 32.5 12.4 15.9 14.5 14.9 29.6 19.4 6.9 16.8 16.7 15.1 26.2 10.2 7.0 21.8 17.8 18.9 27.6 4.6 15.3 19.0 5.9 12.2 28.5 15.9 14.5 7.9 30.5 2.2 16.4 10.2 11.7 9.9 8.7 20.9 12.3 29.8 17.3 16.7 10.9 1.0 24.9 31.9 11.0 43.6 86.3 18.4 16.6 28.8 15.0 0.1 13.4 40.7 50.8 49.0 10.2 35.9 26.7 50.3 19.4 0.3 23.6 45.7 29.7 0.0 1.7 23.9 35.4 35.9 49.6 50.8 54.0 14.7 0.0 1.1 49.3 33.6 26.6 0.1 11.9 34.5 22.6 94.8 21.7 3.1 51.1 33.4 43.8 0.1 45.2 55.6 2.7 12.4 14.6 1.1 86.9 30.0 18.4 54.8 42.2 0.7 6.0 0.0 38.1 0.0 31.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.9 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.1 13.4 20.6 16.7 18.6 15.9 14.5 16.8 16.7 17.8 14.5 16.4 29.8 39.2 25.6 33.5 155.7 17.5 63.5 88.1 45.2 60.3 7.3 56.6 26.5 22.2 101.5 44.1 18.4 4.2 24.8 0.8 75.2 0.0 63.2 4.6 30.6 11.5 46.6 43.9 0.0 889.9 61.3 4.1 28.6 77.5 77.5 1.3 13.4 11.4 40.9 6.4 10.1 55.3 44.2 8.2 1.6 8.8 2.7 17.1 2.2 17.8 200.5 1.7 5.1 0.0 313.1 1278.1 124.2 53.8 18.0 1.0 115.8 68.7 13.4 25.9 0.7 59.2 20.1 41.5 11.3 8.9 27.0 38.1 26.8 3.4 14.1 56.6 157.0 PWP1 IEF-SSP-9502 ENSG00000136045 "PWP1 homolog, endonuclein" Q13610 12 107685799-107713162 "Predicted intracellular proteins" "Ribosome biogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038708 Approved "Nucleoli rim,Golgi apparatus" Yes No "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli rim" "Golgi apparatus" "HPA038708: AB_2676163" "unprognostic (7.06e-2)" "unprognostic (1.82e-1)" "unprognostic (2.70e-2)" "unprognostic (1.92e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (9.65e-4)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.97e-2)" "unprognostic (1.41e-1)" "unprognostic (2.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.89e-1)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.00e-1)" "unprognostic (6.95e-2)" "unprognostic (6.13e-2)" "unprognostic (1.10e-2)" 29.7 20.9 18.6 26.4 19.0 31.9 33.7 18.8 23.6 24.9 29.5 27.7 17.7 30.3 24.8 28.7 24.7 20.4 17.3 18.9 19.1 30.4 32.2 21.4 32.0 17.4 18.0 32.8 25.8 33.0 17.8 29.5 20.0 25.2 26.0 26.9 24.4 27.5 22.9 28.8 21.7 32.3 18.1 23.7 23.1 30.1 18.8 33.2 25.9 17.6 37.4 31.4 24.5 19.0 71.0 86.9 51.8 49.4 70.9 77.2 68.5 72.9 81.9 100.8 84.8 88.5 32.9 108.8 38.4 112.9 68.4 60.7 70.8 77.0 99.2 54.7 80.6 82.9 50.5 103.2 72.7 101.8 56.9 70.2 69.1 93.5 83.0 79.0 119.8 66.0 110.8 29.8 109.1 78.3 71.6 99.3 62.0 64.8 141.2 58.3 61.2 101.4 62.7 98.3 58.4 46.9 59.6 42.4 104.1 64.8 75.3 49.7 94.9 76.7 38.9 63.0 84.1 42.5 62.8 84.9 34.3 55.3 68.7 29.4 20.8 16.2 41.7 27.8 37.8 68.5 40.6 43.9 35.0 64.1 34.5 47.9 6.6 44.2 34.4 47.3 48.6 29.7 18.6 19.0 18.8 23.6 18.9 19.1 17.4 18.0 20.0 18.1 18.8 19.0 44.1 41.7 38.1 13.7 80.1 48.4 52.3 70.6 36.5 50.4 41.0 41.3 22.1 25.8 48.9 27.6 37.5 69.1 48.4 14.6 58.7 69.7 24.4 34.5 47.3 52.0 21.0 52.2 15.6 63.0 74.5 51.6 30.5 35.8 57.6 41.5 43.5 52.0 46.2 33.7 19.0 31.9 26.4 34.3 28.0 11.1 50.4 33.2 30.2 4.7 75.2 41.4 38.1 15.1 16.7 68.0 19.8 44.0 46.0 50.2 24.5 70.8 42.8 46.2 26.3 41.8 50.9 124.3 79.2 41.9 49.7 45.7 44.0 45.8 34.1 40.5 PXN ENSG00000089159 Paxillin P49023 12 120210439-120265771 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 152.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 169.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003841, HPA051309" Supported Enhanced "Focal adhesion sites,Centrosome,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Focal adhesion sites" "Centrosome, Cytosol" "CAB003841: AB_562188, HPA051309: AB_2681436" "unprognostic (4.00e-2)" "unprognostic (1.94e-2)" "unprognostic (3.51e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (1.09e-4)" "prognostic unfavorable (3.72e-5)" "prognostic unfavorable (7.12e-5)" "prognostic unfavorable (1.73e-4)" "unprognostic (3.12e-2)" "unprognostic (9.19e-3)" "unprognostic (2.66e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-2)" "unprognostic (3.35e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-1)" "unprognostic (2.75e-2)" 83.1 60.9 28.7 49.1 30.8 81.4 74.4 27.6 30.5 64.5 33.7 69.0 55.7 56.3 18.7 30.9 72.3 38.2 84.2 28.0 28.5 70.2 29.5 84.6 29.3 37.1 30.8 28.5 34.5 27.8 29.5 73.3 30.3 58.9 49.9 61.8 49.4 40.6 119.2 45.6 61.1 44.5 31.8 72.5 47.5 26.5 36.6 25.9 58.1 46.1 18.4 75.8 53.2 29.2 182.4 87.5 31.3 30.1 60.4 158.1 206.1 151.8 128.6 118.9 61.5 102.5 108.9 12.2 94.6 154.9 115.1 126.0 21.7 272.0 93.0 9.9 18.6 2.3 63.8 37.9 86.8 2.7 3.6 76.5 176.2 125.3 143.9 139.7 211.6 32.2 32.4 19.5 239.3 119.6 11.1 4.1 43.5 77.1 300.8 26.2 51.0 10.8 121.4 171.9 48.7 14.5 133.2 40.3 81.7 72.1 96.1 14.8 289.9 78.9 86.7 103.6 183.9 20.4 12.3 4.6 228.9 27.0 159.2 40.8 44.2 49.2 84.5 15.7 45.3 1.7 38.4 56.0 26.2 1.1 29.5 40.3 169.6 51.8 0.8 4.1 31.4 60.6 28.7 30.8 27.6 30.5 28.0 28.5 37.1 30.8 30.3 31.8 36.6 29.2 93.6 57.7 27.9 11.8 3.0 42.3 40.6 32.8 15.4 7.8 20.3 22.9 14.7 22.8 33.3 42.3 33.3 40.8 61.6 83.1 19.6 31.6 2.1 26.0 16.7 71.0 54.6 6.1 5.1 40.2 152.4 29.7 37.2 28.8 18.3 6.2 62.2 17.2 34.2 11.8 7.7 52.7 24.4 42.3 23.7 2.8 24.2 23.5 26.6 19.7 36.8 9.1 99.9 13.0 9.2 84.8 51.6 18.8 14.5 41.7 56.6 14.6 40.0 33.6 6.6 16.7 12.1 3.5 9.1 8.1 19.5 25.0 34.4 11.3 35.8 42.6 RAB11FIP3 "eferin, KIAA0665, Rab11-FIP3" ENSG00000090565 "RAB11 family interacting protein 3" O75154 16 425649-523011 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 151.1" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028088, HPA028631, HPA030086" Enhanced Enhanced "Nucleoplasm,Vesicles,Cytokinetic bridge,Centriolar satellite,Mitochondria" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Centriolar satellite" "Nucleoplasm, Cytokinetic bridge, Mitochondria" "HPA028088: AB_10601672, HPA028631: AB_10601853, HPA030086: AB_10669596" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.51e-1)" "prognostic favorable (1.22e-4)" "unprognostic (2.87e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.87e-5)" "unprognostic (6.71e-2)" "unprognostic (4.74e-1)" "unprognostic (9.66e-2)" "prognostic favorable (3.16e-5)" "unprognostic (1.12e-1)" "prognostic favorable (7.99e-4)" "unprognostic (1.39e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-1)" "unprognostic (1.44e-1)" 27.9 32.3 18.0 5.3 18.9 7.0 19.5 21.3 22.6 29.6 7.6 35.1 9.0 31.3 5.5 12.3 27.5 7.4 31.4 21.7 14.0 151.1 37.3 25.2 5.8 14.4 15.8 33.8 47.4 15.9 41.5 6.5 15.2 29.9 3.1 6.1 19.3 7.8 52.2 19.5 27.5 7.1 12.7 26.4 22.2 34.6 16.8 5.3 24.8 15.8 3.2 31.7 19.9 19.0 5.9 14.9 14.6 11.9 20.2 13.2 10.0 10.6 11.6 10.7 7.6 11.5 3.0 15.3 11.0 18.7 8.9 5.5 8.9 13.4 3.9 10.8 14.9 7.9 14.8 31.7 20.9 9.5 8.6 12.7 8.8 11.6 9.9 11.7 17.3 10.7 3.5 6.0 14.4 22.5 10.2 15.9 11.7 5.0 6.8 22.8 10.8 4.6 11.3 4.0 13.8 12.0 11.5 13.6 7.5 5.0 7.6 13.9 29.9 14.8 8.8 13.6 7.0 6.9 6.7 18.8 6.5 5.8 11.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 18.0 18.9 21.3 22.6 21.7 14.0 14.4 15.8 15.2 12.7 16.8 19.0 9.4 3.2 1.7 36.9 3.8 3.7 0.7 1.1 2.2 7.7 3.5 4.3 12.4 7.2 4.3 5.5 6.2 1.0 5.7 5.9 27.4 1.6 1.2 6.4 8.7 7.1 3.0 1.7 73.5 1.2 0.2 5.5 2.0 13.1 1.3 8.4 17.9 15.9 0.8 21.9 60.3 3.0 0.0 3.7 1.6 2.6 0.6 4.7 0.0 19.7 0.6 7.2 2.1 46.8 40.7 1.4 3.9 1.9 3.4 0.9 8.1 384.2 3.1 7.6 6.6 5.3 5.4 4.0 2.8 0.3 2.3 0.8 4.4 6.1 5.9 0.3 RAI14 "DKFZp564G013, KIAA1334, NORPEG, RAI13" ENSG00000039560 "Retinoic acid induced 14" Q9P0K7 5 34656328-34832612 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 208.2;Early spermatids: 210.1;Late spermatids: 364.3;Syncytiotrophoblasts: 156.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 267.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 23.8" "HPA036949, HPA036950" Supported Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Actin filaments, Cytosol" "HPA036949: AB_10670568, HPA036950: AB_10669721" "unprognostic (7.63e-2)" "unprognostic (9.86e-2)" "unprognostic (4.87e-2)" "unprognostic (1.40e-1)" "unprognostic (3.38e-2)" "unprognostic (4.75e-2)" "unprognostic (5.49e-2)" "unprognostic (6.18e-2)" "unprognostic (6.28e-2)" "unprognostic (2.62e-1)" "unprognostic (8.18e-2)" "unprognostic (4.58e-2)" "prognostic unfavorable (9.75e-4)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.33e-1)" "unprognostic (4.81e-2)" "unprognostic (4.34e-2)" 10.6 9.0 10.1 21.6 14.5 2.4 9.8 13.3 9.8 51.2 17.5 22.1 7.0 53.6 6.2 10.0 13.8 18.7 6.8 8.0 9.4 18.9 27.5 26.2 14.7 18.1 13.9 9.5 7.9 10.8 4.9 34.6 17.1 11.4 10.3 10.2 16.5 25.4 1.9 19.5 7.5 58.0 15.6 39.4 10.8 39.2 12.7 6.3 10.1 2.3 10.2 43.0 14.3 20.0 12.5 48.5 55.2 37.1 29.0 100.9 70.3 147.0 118.3 83.3 83.0 36.7 15.6 2.9 57.0 72.5 90.5 8.2 64.0 109.0 179.2 0.2 30.5 20.6 43.3 22.9 90.0 0.5 1.9 94.8 34.0 149.4 118.1 136.7 267.4 4.6 29.4 1.0 110.1 10.0 2.3 0.7 43.3 7.8 47.0 18.2 84.1 0.6 97.4 70.1 14.4 7.9 86.8 12.8 39.5 80.5 14.9 2.3 173.2 134.1 71.7 33.5 65.1 3.1 0.1 0.4 113.5 0.4 53.5 0.9 0.2 0.1 0.9 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.4 0.8 0.0 0.1 0.0 0.0 10.1 14.5 13.3 9.8 8.0 9.4 18.1 13.9 17.1 15.6 12.7 20.0 16.2 105.8 208.2 33.3 0.9 12.0 32.2 46.7 23.9 3.2 27.8 9.9 5.2 7.2 81.8 35.0 68.8 32.3 0.6 17.9 7.9 36.1 210.1 35.7 36.1 96.1 1.8 2.7 6.6 28.5 75.3 25.0 11.2 36.1 3.8 22.7 17.2 23.0 7.2 15.2 6.0 1.1 16.2 1.6 4.3 364.3 72.1 4.6 5.4 15.0 1.0 19.3 0.0 31.2 60.1 53.3 5.1 31.6 0.1 26.6 6.3 25.3 24.8 5.1 0.0 6.0 33.4 9.0 9.2 6.4 15.8 156.1 3.4 11.4 2.6 61.5 RALA RAL ENSG00000006451 "RAS like proto-oncogene A" P11233 7 39623565-39708120 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Exocytosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 292.4;Pancreatic endocrine cells: 411.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 302.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047037, HPA065232" Approved Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "Focal adhesion sites" "HPA047037: , HPA065232: AB_2685440" "unprognostic (1.20e-3)" "unprognostic (1.03e-2)" "unprognostic (2.91e-1)" "unprognostic (7.73e-3)" "unprognostic (1.98e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (7.71e-2)" "unprognostic (2.17e-1)" "prognostic favorable (7.46e-4)" "prognostic unfavorable (6.30e-4)" "unprognostic (3.32e-1)" "unprognostic (4.95e-3)" "unprognostic (5.38e-2)" "unprognostic (7.15e-2)" "unprognostic (2.79e-1)" "unprognostic (2.95e-2)" 27.8 32.1 32.4 20.7 35.5 7.4 23.8 35.8 37.3 23.0 30.2 30.9 32.6 20.4 20.1 54.0 19.6 26.8 17.6 33.7 34.3 20.6 21.4 41.8 21.4 37.0 35.7 22.2 16.0 22.6 10.5 32.5 36.4 15.4 31.6 13.0 19.8 15.8 25.8 26.9 30.9 21.1 37.7 18.8 33.8 12.7 34.9 25.5 17.4 19.1 35.2 23.5 22.0 39.8 81.0 18.3 44.1 38.6 81.7 67.6 30.0 69.7 99.7 61.8 67.9 46.1 39.0 41.5 25.5 54.1 58.1 81.5 62.5 45.0 105.5 40.2 29.6 32.4 28.1 34.1 132.1 56.9 43.8 53.7 54.0 110.0 155.4 76.7 302.4 39.7 65.9 27.0 63.2 26.3 40.3 66.7 123.0 88.0 35.9 49.4 40.2 36.3 63.1 37.3 78.0 75.6 42.8 67.7 49.4 78.7 63.5 60.9 98.0 36.4 32.4 46.3 50.7 47.6 39.1 50.3 40.5 58.0 67.2 38.3 13.5 15.7 12.5 15.6 15.7 15.8 20.1 16.2 22.6 18.0 25.6 22.9 6.1 23.2 12.6 14.5 28.1 15.9 32.4 35.5 35.8 37.3 33.7 34.3 37.0 35.7 36.4 37.7 34.9 39.8 66.5 83.3 38.1 25.5 40.5 90.1 37.3 75.1 41.5 14.6 41.3 63.5 37.3 40.0 50.3 23.9 6.2 52.1 28.4 80.1 21.5 165.4 98.2 56.5 64.8 121.5 47.8 35.1 47.6 122.0 92.5 52.4 42.3 99.9 31.7 41.8 75.0 27.8 101.9 11.8 48.4 53.1 144.5 33.0 292.4 17.4 47.8 73.0 30.2 44.0 97.0 37.3 23.7 39.2 37.0 411.0 73.8 69.6 48.6 61.0 70.8 38.6 36.6 16.6 32.9 26.5 131.9 59.1 71.6 113.4 109.4 62.0 37.0 53.9 58.7 64.5 RAPGEF5 "GFR, KIAA0277, MR-GEF" ENSG00000136237 "Rap guanine nucleotide exchange factor 5" Q92565 7 22118236-22357154 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 152.1;parathyroid gland: 387.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 504.6;Inhibitory neurons: 193.4;Microglial cells: 138.7;Oligodendrocytes: 640.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 21.1;HUVEC TERT2: 45.0;SCLC-21H: 34.1;TIME: 25.8;U-698: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057821, HPA076772" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA057821: AB_2683538, HPA076772: AB_2686814" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (5.22e-2)" "prognostic favorable (3.52e-5)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (1.31e-1)" "unprognostic (3.76e-2)" "unprognostic (6.36e-3)" "unprognostic (6.57e-2)" "unprognostic (2.55e-1)" "unprognostic (8.26e-3)" 21.0 12.7 30.7 7.0 82.9 0.9 16.4 76.1 58.5 8.9 2.9 9.5 7.5 8.8 4.8 13.9 8.3 16.8 16.8 45.7 46.9 16.7 21.8 37.5 14.3 115.3 71.8 6.5 20.1 387.8 7.4 67.2 107.1 5.1 11.0 4.2 7.6 5.7 5.1 9.2 8.3 12.1 82.0 50.9 7.0 6.4 59.8 15.7 11.7 11.1 10.7 9.3 11.9 152.1 2.8 0.0 4.6 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 5.5 1.4 21.1 1.1 0.3 0.7 13.0 2.8 1.9 0.0 0.0 4.2 0.3 0.0 5.4 0.1 0.0 0.1 0.5 2.4 1.3 0.7 0.7 45.0 5.9 4.8 0.1 0.0 1.2 3.0 0.1 3.6 5.4 4.0 5.2 0.0 7.4 4.2 1.9 34.1 9.0 0.5 6.0 0.1 0.7 3.0 0.1 25.8 0.0 1.0 0.4 1.1 10.9 2.5 37.4 0.5 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 82.9 76.1 58.5 45.7 46.9 115.3 71.8 107.1 82.0 59.8 152.1 125.5 9.6 16.5 13.4 3.1 11.0 4.2 2.4 86.0 30.6 8.8 5.5 10.0 15.7 3.8 0.0 0.0 0.3 0.6 16.0 1.9 6.5 61.5 3.3 1.2 70.1 7.2 0.4 504.6 7.0 0.1 5.3 16.3 10.8 8.2 0.1 86.0 6.3 0.2 23.5 193.4 18.3 2.0 3.1 2.0 65.2 1.8 0.9 7.2 138.7 0.0 0.6 0.0 28.1 640.8 5.0 20.3 4.9 12.9 3.0 18.1 0.3 0.5 1.6 85.5 1.4 21.5 1.2 1.6 19.8 11.2 0.3 2.4 1.9 10.1 4.4 RASIP1 "FLJ20401, RAIN" ENSG00000105538 "Ras interacting protein 1" Q5U651 19 48720585-48740610 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 121.8;Endothelial cells: 83.9;Hepatic stellate cells: 94.2;Theca cells: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 14.7;HeLa: 13.9;HUVEC TERT2: 38.5;SiHa: 21.1;TIME: 52.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077251 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA077251: AB_2732337" "unprognostic (9.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (3.64e-2)" "prognostic favorable (7.17e-5)" "unprognostic (8.44e-2)" "unprognostic (2.63e-1)" "unprognostic (3.10e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.46e-4)" "unprognostic (5.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-2)" "unprognostic (1.32e-1)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" 24.4 7.0 5.9 2.6 4.3 0.7 21.0 4.4 4.6 9.2 1.4 5.6 2.5 11.2 1.1 5.1 9.9 3.8 18.8 3.6 4.0 12.6 2.6 27.9 2.2 4.9 5.3 4.9 13.2 1.6 4.1 7.9 5.9 5.5 0.7 0.1 4.8 2.7 7.7 6.0 5.7 4.2 4.5 16.8 10.3 6.8 7.3 1.5 10.5 4.0 1.4 7.6 7.7 3.6 10.2 0.1 0.2 0.2 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.6 1.1 0.8 2.2 0.0 0.0 2.5 0.2 2.2 0.0 0.0 14.7 0.2 13.9 0.4 2.2 0.0 0.7 2.2 1.2 0.0 0.0 0.0 38.5 1.3 1.3 0.1 0.0 0.9 0.0 1.3 0.3 0.4 0.0 0.2 0.0 0.4 0.0 0.8 6.7 0.5 21.1 0.0 0.0 0.1 0.1 0.0 52.4 0.0 0.4 0.2 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 4.3 4.4 4.6 3.6 4.0 4.9 5.3 5.9 4.5 7.3 3.6 121.8 0.0 1.3 0.0 1.2 6.5 5.7 2.0 0.6 1.1 5.9 10.8 7.3 1.5 1.2 1.8 0.0 0.4 0.7 0.1 0.0 0.7 5.9 3.2 4.8 83.9 0.0 2.7 3.4 0.7 1.9 9.5 2.0 3.8 0.0 6.0 94.2 1.9 0.7 6.7 1.1 0.1 4.1 6.3 3.0 5.2 10.2 1.0 19.6 16.9 0.0 2.1 0.0 1.5 1.5 0.8 0.0 11.3 1.4 10.1 0.2 0.3 2.1 0.7 19.7 1.9 6.2 1.0 11.0 3.7 6.0 0.3 1.0 40.2 0.2 6.4 RBM3 IS1-RNPL ENSG00000102317 "RNA binding motif protein 3" P98179 X 48574449-48581162 "Predicted intracellular proteins" "Stress response" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 1442.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "HPA003624, CAB062559" Enhanced Enhanced Nucleoplasm NA NA 130000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "CAB062559: AB_2665621, HPA003624: AB_10602123" "unprognostic (1.07e-2)" "unprognostic (1.14e-3)" "prognostic favorable (3.07e-7)" "unprognostic (1.65e-3)" "unprognostic (2.87e-1)" "unprognostic (4.05e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (9.37e-2)" "unprognostic (1.63e-2)" "unprognostic (2.65e-2)" "unprognostic (2.02e-2)" "unprognostic (6.18e-2)" "unprognostic (1.10e-1)" "unprognostic (5.05e-2)" "unprognostic (3.92e-2)" "unprognostic (1.59e-1)" 246.8 129.7 21.7 143.2 23.7 301.8 200.9 23.0 33.2 82.3 27.5 122.4 102.1 118.2 89.4 147.1 101.7 71.9 100.7 22.3 27.9 89.2 71.1 130.5 158.5 27.9 24.0 99.3 167.2 94.2 80.1 104.0 26.5 75.7 146.0 51.4 126.0 81.8 112.3 195.3 102.6 114.9 28.7 128.5 114.2 55.9 23.4 156.9 90.1 38.3 206.1 135.0 101.7 29.3 128.2 168.7 172.5 187.3 42.4 226.3 117.2 156.0 272.3 381.6 273.6 173.7 322.5 241.4 50.0 302.3 75.9 107.1 153.2 209.1 304.1 236.5 206.7 126.2 270.5 164.0 153.0 360.8 248.0 168.1 143.8 129.7 124.3 46.2 320.4 131.7 69.8 194.6 268.6 215.9 304.9 209.3 100.5 33.3 230.1 280.7 181.4 196.5 177.7 201.8 70.1 179.1 152.2 206.9 187.5 83.7 272.2 363.6 440.7 127.0 213.0 425.8 278.2 93.7 114.0 279.1 176.5 208.0 263.0 33.0 187.0 30.7 118.4 211.9 141.7 147.5 120.6 119.7 264.1 101.5 120.6 119.5 28.7 150.9 187.0 185.0 137.5 256.3 21.7 23.7 23.0 33.2 22.3 27.9 27.9 24.0 26.5 28.7 23.4 29.3 336.2 166.7 172.1 18.6 391.7 519.4 182.9 379.4 157.6 58.9 326.1 260.5 76.8 154.4 196.7 53.3 47.9 459.9 392.1 165.8 176.1 482.2 6.0 114.6 193.8 292.9 247.4 287.0 18.4 1442.0 726.9 274.2 164.1 234.3 265.2 144.9 195.9 74.6 433.2 42.1 17.7 360.2 136.3 439.5 783.6 17.1 245.7 339.3 522.9 18.7 571.7 181.8 358.4 15.1 18.0 915.3 235.9 147.4 317.7 119.0 143.3 164.3 84.6 87.0 131.5 378.4 299.4 43.6 200.8 285.2 507.8 489.3 352.5 178.2 368.0 202.6 RELL1 ENSG00000181826 "RELT like 1" Q8IUW5 4 37590800-37686376 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.7" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Microglial cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 59.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013377 Approved Supported "Plasma membrane,Microtubules" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Microtubules" "HPA013377: AB_1844403" "unprognostic (1.70e-1)" "unprognostic (1.70e-1)" "unprognostic (4.78e-2)" "unprognostic (5.30e-2)" "unprognostic (6.80e-2)" "unprognostic (7.28e-2)" "unprognostic (7.35e-2)" "unprognostic (2.67e-2)" "unprognostic (2.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (7.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (6.15e-2)" "unprognostic (1.71e-2)" 13.5 2.4 10.6 4.9 15.5 25.6 7.8 20.1 14.9 5.1 9.3 8.3 6.2 5.5 2.7 6.4 5.1 6.1 6.0 8.0 13.3 3.9 4.8 6.6 4.7 29.7 19.3 3.5 2.3 1.5 1.4 6.1 27.7 3.0 6.6 3.1 3.5 3.8 15.8 12.4 5.5 6.0 24.4 7.3 12.3 1.6 20.1 3.7 12.5 4.3 4.8 7.8 4.1 39.7 4.8 5.1 12.9 11.1 10.8 6.2 10.8 8.0 6.9 5.5 7.2 16.8 5.7 1.3 5.7 6.9 9.8 4.3 4.1 7.2 9.6 0.2 2.1 1.8 4.7 18.2 8.1 6.0 4.5 10.6 10.2 7.5 8.2 3.4 24.9 3.3 3.1 5.0 6.4 4.4 7.5 8.3 3.2 6.9 1.5 2.5 45.0 2.2 13.2 5.9 2.9 8.5 6.1 6.6 10.6 3.2 18.0 3.2 29.6 13.8 8.7 10.1 9.5 2.5 2.6 7.3 11.7 12.8 11.4 0.8 15.2 27.4 5.1 5.7 6.3 0.7 6.2 4.9 8.5 0.2 5.3 7.0 59.3 7.7 5.5 9.8 5.5 5.1 10.6 15.5 20.1 14.9 8.0 13.3 29.7 19.3 27.7 24.4 20.1 39.7 30.5 9.6 3.1 16.3 2.9 3.3 2.5 1.7 10.8 0.4 8.1 9.5 2.1 5.7 3.9 0.0 0.0 1.4 9.8 8.4 0.0 3.1 6.5 5.5 9.9 14.4 1.2 3.4 3.3 8.6 3.6 10.7 22.4 2.4 2.5 0.5 6.4 0.9 2.6 3.3 2.4 1.6 0.0 3.2 2.7 8.1 3.7 9.2 1.8 36.5 4.1 4.0 0.0 22.6 12.5 10.3 2.9 6.0 15.5 2.7 6.7 0.2 3.3 1.4 13.1 18.8 16.4 0.8 0.3 5.5 4.7 5.2 10.6 5.1 1.1 3.8 RELN "PRO1598, RL" ENSG00000189056 Reelin P78509 7 103471381-103989658 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein, Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 64.4" "Group enriched" "Detected in some" 8 "Hepatic stellate cells: 128.5;Inhibitory neurons: 372.4" "Cancer enhanced" "Detected in many" "liver cancer: 5.7" "Region enriched" "Detected in many" 10 "cerebellum: 64.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 16.2;PC-3: 8.6;SCLC-21H: 11.1;SH-SY5Y: 13.7;TIME: 33.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 110.0" HPA077891 Approved "Golgi apparatus,Vesicles" "Secreted in brain" NA NA 30000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Vesicles "HPA077891: " "unprognostic (1.42e-1)" "unprognostic (2.93e-3)" "unprognostic (4.31e-2)" "unprognostic (1.29e-4)" "unprognostic (1.30e-1)" "unprognostic (6.95e-2)" "unprognostic (1.85e-1)" "unprognostic (8.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.48e-2)" "unprognostic (3.31e-3)" "unprognostic (3.86e-1)" "unprognostic (2.02e-2)" "unprognostic (1.43e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.06e-2)" 1.3 1.8 2.0 0.6 1.8 0.0 2.7 64.4 3.8 1.5 0.6 0.8 0.2 0.4 0.1 0.8 2.8 0.7 1.7 3.3 6.4 0.4 13.4 0.5 0.4 2.6 4.2 0.4 0.1 0.0 0.5 0.0 6.3 0.6 0.9 2.9 0.8 0.9 0.2 0.6 0.9 0.7 3.9 0.3 0.5 0.7 0.5 0.0 1.7 1.1 0.2 0.7 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 4.3 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 1.9 0.0 0.0 0.0 11.1 13.7 0.0 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.8 64.4 3.8 3.3 6.4 2.6 4.2 6.3 3.9 0.5 0.5 1.0 0.0 0.0 9.1 0.5 0.6 0.0 0.0 0.6 30.2 0.5 0.4 5.1 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 13.6 0.1 0.0 8.3 0.0 7.0 2.6 1.2 0.1 7.5 0.0 0.1 0.0 0.0 128.5 3.3 0.2 0.0 372.4 0.0 0.0 5.3 2.2 6.1 0.0 0.1 0.0 2.8 0.0 0.2 0.0 3.0 10.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.8 0.7 0.1 0.8 0.0 0.6 0.3 0.4 0.0 0.0 0.0 RGS4 SCZD9 ENSG00000117152 "Regulator of G protein signaling 4" P49798 1 163068775-163076802 "Disease related genes, Predicted intracellular proteins" "Signal transduction inhibitor" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 34.6;brain: 120.6" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 51.6;Excitatory neurons: 115.4;Inhibitory neurons: 59.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 120.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "hTERT-RPE1: 527.4;LHCN-M2: 244.2;SH-SY5Y: 429.5;TIME: 959.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030802 Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA030802: AB_10602295" "unprognostic (1.03e-1)" "unprognostic (1.84e-1)" "unprognostic (3.02e-2)" "unprognostic (6.84e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (8.26e-2)" "unprognostic (1.27e-1)" "unprognostic (5.34e-3)" "unprognostic (1.82e-1)" "unprognostic (6.45e-2)" "unprognostic (2.12e-2)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.97e-4)" "prognostic unfavorable (1.92e-4)" "unprognostic (1.00e-1)" "unprognostic (8.33e-2)" "unprognostic (2.30e-2)" 8.2 34.6 35.6 3.0 46.7 0.0 1.7 0.0 120.6 5.9 0.0 4.3 4.2 7.8 1.2 9.7 7.3 18.3 8.7 49.3 42.2 1.9 4.0 3.0 3.7 0.0 5.2 2.2 4.7 2.3 14.3 1.6 2.0 4.7 2.5 6.7 0.8 6.5 0.4 0.3 2.8 4.7 0.0 1.7 8.4 3.0 0.0 1.8 3.1 1.4 0.4 5.9 1.4 39.7 0.3 0.0 1.2 7.2 25.1 115.9 0.2 77.8 92.1 12.6 31.9 0.0 0.3 0.3 35.6 50.2 0.5 0.2 0.0 0.1 42.2 0.4 0.1 0.3 0.0 0.0 11.0 0.2 0.2 19.0 0.0 123.0 14.3 527.4 127.5 0.0 0.1 0.6 244.2 0.0 0.0 0.5 6.5 0.0 9.6 0.1 0.0 0.4 0.0 0.0 2.9 429.5 0.0 0.1 0.2 4.0 0.1 0.1 959.6 91.5 5.2 19.1 129.5 0.1 0.1 0.3 11.4 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.6 46.7 0.0 120.6 49.3 42.2 0.0 5.2 2.0 0.0 0.0 39.7 0.8 0.0 0.0 15.7 0.0 0.3 1.7 0.1 0.0 4.3 0.7 0.0 0.7 0.0 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.3 12.6 0.5 16.9 2.6 51.6 0.0 115.4 0.2 0.1 20.2 0.0 0.4 0.0 1.1 1.1 0.0 0.4 0.0 59.9 0.0 0.0 0.0 0.5 3.8 0.0 0.1 0.0 13.1 0.0 15.7 0.0 13.0 13.0 2.7 0.1 0.0 0.0 0.5 0.0 0.0 0.7 1.6 0.0 0.2 17.0 0.1 0.6 0.5 0.3 0.1 0.6 0.1 0.1 0.3 RGS7BP R7BP ENSG00000186479 "Regulator of G protein signaling 7 binding protein" Q6MZT1 5 64506015-64612319 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.0" "Group enriched" "Detected in some" 5 "Excitatory neurons: 122.5;Inhibitory neurons: 170.6;Oligodendrocyte precursor cells: 67.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 26.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HUVEC TERT2: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039600 Approved Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Actin filaments" "HPA039600: AB_2676591" "unprognostic (2.93e-1)" "unprognostic (3.39e-1)" "unprognostic (7.35e-2)" "unprognostic (4.77e-2)" "unprognostic (7.57e-2)" "unprognostic (8.59e-2)" "unprognostic (5.22e-2)" "unprognostic (8.81e-3)" "unprognostic (1.86e-2)" "unprognostic (7.64e-2)" "unprognostic (5.49e-3)" "unprognostic (1.83e-1)" "unprognostic (1.65e-3)" "unprognostic (3.39e-3)" "unprognostic (2.06e-3)" "unprognostic (6.46e-2)" "unprognostic (8.50e-3)" 1.9 3.2 3.2 0.5 12.2 0.0 0.5 1.0 26.0 4.0 0.0 0.6 0.9 2.3 3.7 1.7 7.8 1.7 2.6 7.2 1.2 2.0 1.0 1.4 0.3 0.2 3.3 2.4 0.2 0.1 0.8 0.0 0.0 5.3 0.7 4.8 1.8 7.4 0.1 0.3 1.0 1.4 0.0 0.7 0.8 0.8 10.2 0.0 0.3 1.0 0.1 0.9 0.5 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 12.2 1.0 26.0 7.2 1.2 0.2 3.3 0.0 0.0 10.2 5.0 0.4 0.0 0.0 5.5 0.1 0.0 0.1 0.1 0.6 6.5 0.7 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.1 5.1 4.6 0.0 2.7 122.5 0.0 0.0 0.8 0.0 4.7 0.0 0.1 23.2 0.1 0.0 0.0 170.6 0.0 0.0 0.3 0.0 1.9 7.2 0.1 0.0 12.2 0.0 3.6 0.0 67.8 6.4 0.0 0.0 13.9 0.0 0.1 0.0 0.2 2.2 2.1 6.6 0.1 13.2 0.3 0.6 0.4 0.0 0.0 0.2 0.0 0.0 0.2 RHOJ "ARHJ, FLJ14445, RASL7B, TCL" ENSG00000126785 "Ras homolog family member J" Q9H4E5 14 63204114-63293508 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 41.0;Astrocytes: 176.0;Endothelial cells: 72.5;Hepatic stellate cells: 41.4;Microglial cells: 35.6;Oligodendrocyte precursor cells: 43.2;Skeletal myocytes: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 63.8;HUVEC TERT2: 375.4;TIME: 100.9;WM-115: 106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003050 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003050: AB_1079812" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.37e-2)" "unprognostic (2.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.77e-2)" "unprognostic (2.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (3.04e-3)" "unprognostic (1.42e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (3.50e-3)" "unprognostic (4.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.06e-3)" 19.6 3.3 12.5 8.5 14.6 0.1 17.4 10.8 16.9 12.9 8.5 14.2 7.5 27.9 17.3 15.5 18.5 25.3 17.9 14.0 11.1 11.7 4.2 21.5 9.6 10.9 11.0 14.2 4.4 3.5 6.4 9.3 11.0 11.8 10.7 5.5 8.4 13.8 7.9 7.6 9.8 31.4 8.3 12.6 9.3 2.8 14.5 3.1 13.8 13.4 4.9 19.7 9.4 13.0 0.0 0.0 63.8 0.0 0.0 0.0 0.0 10.6 42.6 3.6 6.2 0.0 0.0 0.0 5.9 0.8 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.3 0.0 0.1 8.0 35.8 375.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 5.1 0.0 0.4 0.0 0.1 0.1 0.0 0.0 14.6 1.1 0.1 0.0 100.9 0.1 1.1 0.8 6.1 0.0 0.0 0.0 0.0 0.0 106.5 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 12.5 14.6 10.8 16.9 14.0 11.1 10.9 11.0 11.0 8.3 14.5 13.0 41.0 0.0 1.3 176.0 0.3 5.9 0.3 0.1 0.0 0.3 1.2 5.2 3.8 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 1.4 0.5 0.3 6.7 72.5 0.0 0.0 11.1 0.9 0.0 31.0 0.0 0.3 0.0 0.5 41.4 0.5 0.1 0.0 2.2 0.0 0.0 1.9 7.7 1.6 11.8 1.0 3.6 35.6 0.0 11.1 0.0 43.2 0.4 0.1 0.0 16.1 2.5 0.6 0.0 0.0 0.0 0.4 6.6 34.6 17.0 0.1 0.4 0.9 4.8 0.1 0.6 6.9 0.0 1.4 RIN2 RASSF4 ENSG00000132669 "Ras and Rab interactor 2" Q8WYP3 20 19757606-20002457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 198.5;Microglial cells: 191.1;Oligodendrocyte precursor cells: 296.6;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "PC-3: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034641 Approved Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoli, Golgi apparatus" "HPA034641: AB_10671230" "unprognostic (8.23e-3)" "unprognostic (8.09e-3)" "unprognostic (3.71e-2)" "unprognostic (1.97e-1)" "unprognostic (3.12e-2)" "unprognostic (3.86e-2)" "unprognostic (1.61e-2)" "unprognostic (3.69e-2)" "unprognostic (2.69e-2)" "unprognostic (1.78e-3)" "unprognostic (2.49e-1)" "unprognostic (6.27e-2)" "prognostic favorable (8.34e-6)" "unprognostic (3.10e-1)" "unprognostic (2.08e-2)" "unprognostic (8.02e-3)" "unprognostic (3.63e-2)" 14.2 6.4 8.7 8.6 13.5 6.1 9.5 9.4 7.1 14.4 14.4 12.5 13.3 14.1 3.9 13.6 11.7 17.8 18.7 9.5 10.8 12.1 5.3 18.3 4.7 14.6 13.2 15.0 6.5 4.6 1.4 19.8 12.8 9.4 12.7 5.5 15.6 13.5 9.4 8.2 14.7 16.2 9.5 16.8 8.8 1.8 12.7 3.0 13.7 13.2 5.3 8.1 3.8 14.0 6.7 22.4 4.1 13.7 23.3 14.2 13.1 5.9 22.8 5.7 3.0 10.0 5.8 0.0 24.0 14.6 10.6 24.7 0.1 33.5 6.3 2.7 0.1 0.0 3.5 0.8 5.4 0.0 0.1 21.7 6.1 10.7 11.9 13.4 30.6 0.0 0.1 0.4 17.0 5.3 0.1 0.4 0.7 3.2 47.1 0.1 13.8 3.4 7.2 9.2 3.5 0.9 5.3 23.7 0.1 4.1 2.0 1.4 33.7 11.4 2.9 8.1 9.2 0.1 0.1 0.0 8.0 0.0 2.0 0.2 1.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 1.0 0.1 0.0 0.4 8.7 13.5 9.4 7.1 9.5 10.8 14.6 13.2 12.8 9.5 12.7 14.0 52.3 64.1 17.5 198.5 1.4 41.9 18.5 30.9 24.5 6.1 25.6 18.4 34.3 14.3 23.7 31.3 8.4 6.8 0.2 30.4 43.0 17.5 1.0 50.0 47.3 52.7 14.4 0.4 5.9 34.5 7.4 33.2 10.7 87.3 0.0 32.4 105.3 4.2 100.2 6.7 82.8 17.2 26.4 60.3 40.3 0.8 19.3 37.7 21.4 191.1 21.4 33.2 1.0 296.6 202.4 26.2 10.5 15.4 0.8 22.3 23.0 50.1 27.1 1.9 0.0 25.4 22.6 0.5 0.8 33.6 54.0 7.1 2.9 43.1 21.9 32.2 RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 9121.6" "Cell type enhanced" "Detected in many" "Adipocytes: 826.6;Alveolar cells type 1: 929.5;Alveolar cells type 2: 818.4;Gastric mucus-secreting cells: 821.1;Hepatic stellate cells: 650.3;Hofbauer cells: 1583.4;Intestinal goblet cells: 663.8;Macrophages: 632.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 286.8;OE19: 67.4;RT4: 114.2;TIME: 179.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 1100000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" 694.2 501.3 336.6 131.3 466.1 6.2 353.3 404.4 556.1 203.9 294.9 378.4 176.7 139.4 112.0 194.0 232.0 406.4 377.7 351.3 380.9 253.0 54.5 775.9 187.8 438.9 408.3 190.6 9121.6 60.6 43.9 897.4 403.7 83.9 425.2 3.1 168.0 149.7 127.6 118.1 201.8 285.6 357.3 353.1 1003.5 977.5 465.4 177.6 119.7 280.6 68.8 374.7 107.9 533.7 0.0 1.4 0.5 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 6.7 0.0 0.3 1.7 0.0 2.2 0.6 0.0 1.4 0.0 0.1 0.1 5.3 0.1 0.8 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 286.8 0.0 31.4 0.4 0.0 0.0 0.3 2.0 1.2 67.4 0.0 0.2 0.1 1.5 0.2 114.2 1.2 1.4 0.0 0.8 0.3 2.0 0.3 0.1 179.3 0.0 2.7 1.8 0.3 0.6 0.1 0.1 4.6 0.1 3.8 1.6 9.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.0 5.0 0.0 2.4 336.6 466.1 404.4 556.1 351.3 380.9 438.9 408.3 403.7 357.3 465.4 533.7 826.6 929.5 818.4 1.6 11.1 35.6 1.0 1.9 15.9 0.1 6.2 11.7 59.8 27.1 174.0 16.5 0.0 12.9 5.7 261.8 0.0 8.8 20.0 3.8 1.9 581.7 48.7 28.0 0.5 315.2 14.6 58.4 821.1 3.4 25.2 103.8 650.3 7.9 1583.4 1.7 0.8 663.8 8.2 267.9 197.5 57.1 32.0 632.8 40.9 36.5 3.4 0.8 0.0 1.0 232.3 286.8 246.7 10.9 7.5 1.4 81.7 0.9 34.9 2.7 98.6 20.7 31.4 16.4 6.6 16.6 28.1 25.9 10.6 392.8 162.9 3.8 RNF121 FLJ11099 ENSG00000137522 "Ring finger protein 121" Q9H920 11 71929018-71997597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046041 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA046041: AB_10965850" "unprognostic (1.36e-2)" "unprognostic (8.84e-2)" "unprognostic (9.72e-2)" "unprognostic (1.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.38e-2)" "unprognostic (1.41e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" "unprognostic (6.54e-2)" "unprognostic (1.85e-2)" "unprognostic (1.90e-1)" "prognostic favorable (2.72e-6)" "unprognostic (1.54e-1)" "unprognostic (1.81e-1)" "unprognostic (2.57e-2)" "unprognostic (1.70e-1)" 7.2 9.5 8.8 6.6 8.7 5.8 11.3 8.5 9.2 9.8 9.7 8.1 15.9 8.4 20.0 7.4 11.6 7.8 10.0 8.8 9.0 16.4 11.5 7.6 8.1 8.8 9.1 11.2 10.9 24.3 9.5 11.1 8.8 10.6 10.3 15.7 15.1 13.6 17.2 8.3 13.9 11.8 9.0 6.7 9.2 8.7 9.1 7.7 12.9 14.9 10.4 9.1 7.1 8.7 10.9 22.7 20.5 14.6 19.1 15.2 13.8 16.7 17.7 25.4 26.9 46.0 20.9 9.2 14.9 18.5 26.7 22.1 22.7 21.2 26.7 13.8 13.1 14.0 21.5 21.9 14.3 12.8 11.5 14.8 17.9 28.7 18.2 27.9 46.7 13.5 23.2 8.6 22.7 23.5 9.0 14.1 13.7 43.4 21.9 11.0 44.5 7.9 28.3 18.4 13.7 14.6 22.9 20.4 30.4 20.6 22.5 9.5 32.8 19.0 17.2 11.8 14.6 9.6 10.2 9.4 16.5 8.3 17.1 4.4 2.2 2.2 3.0 2.9 3.5 3.2 2.3 2.4 2.3 1.3 2.7 2.9 1.2 3.2 2.1 3.7 2.1 2.9 8.8 8.7 8.5 9.2 8.8 9.0 8.8 9.1 8.8 9.0 9.1 8.7 9.6 6.4 9.6 12.7 9.4 8.8 11.2 22.8 10.2 16.1 12.1 10.9 9.7 12.8 13.3 20.2 20.9 32.0 17.9 15.2 7.9 26.0 6.3 8.9 10.3 6.5 9.6 13.0 19.3 32.3 26.5 11.8 9.2 10.9 7.0 11.6 8.9 14.4 14.2 10.1 16.9 13.2 26.4 6.6 12.9 3.0 13.1 7.6 10.6 15.0 15.0 19.0 10.3 18.1 19.0 29.0 11.0 12.4 17.1 10.3 31.0 20.9 10.3 21.1 19.7 10.0 14.2 25.1 19.6 6.4 5.8 31.1 10.0 13.4 9.4 9.9 RNF152 FLJ39176 ENSG00000176641 "Ring finger protein 152" Q8N8N0 18 61808067-61894247 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.3;choroid plexus: 62.3;kidney: 56.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 96.4;Proximal tubular cells: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 21.5;SH-SY5Y: 13.4;TIME: 14.2;U-138 MG: 21.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.30e-2)" "unprognostic (1.97e-2)" "unprognostic (1.64e-1)" "unprognostic (8.55e-3)" "unprognostic (2.05e-1)" "unprognostic (2.09e-1)" "unprognostic (2.96e-3)" "unprognostic (3.62e-1)" "unprognostic (1.51e-2)" "unprognostic (8.13e-2)" "unprognostic (5.14e-2)" "unprognostic (6.73e-2)" "prognostic favorable (1.13e-8)" "prognostic unfavorable (2.85e-5)" "unprognostic (3.26e-2)" "unprognostic (2.82e-2)" "unprognostic (4.83e-2)" 7.4 3.4 5.4 0.9 13.9 0.9 6.7 48.3 5.3 8.2 62.3 7.2 1.7 6.3 3.6 4.5 5.2 3.8 7.6 6.1 10.6 56.5 22.1 7.0 0.5 25.5 13.7 4.0 2.5 2.4 2.9 6.5 28.7 5.3 6.6 5.0 14.0 2.8 2.3 11.4 5.5 4.1 8.5 0.6 6.3 1.3 21.1 0.6 5.4 2.3 0.8 4.2 7.5 14.9 0.0 0.0 4.8 1.0 4.4 0.6 0.0 3.1 9.4 0.7 0.5 0.0 0.1 0.1 0.9 4.9 0.1 21.5 5.9 11.4 1.3 0.0 0.6 0.0 0.0 0.0 2.3 0.0 0.1 0.7 8.1 3.6 2.4 2.1 8.7 0.1 0.0 0.1 1.4 0.9 0.8 0.0 0.3 0.7 0.0 0.3 3.1 0.0 0.5 3.7 3.9 13.4 0.0 8.7 1.5 4.2 5.1 0.0 14.2 21.6 2.2 0.0 0.5 0.1 0.0 0.0 0.7 0.0 7.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.4 13.9 48.3 5.3 6.1 10.6 25.5 13.7 28.7 8.5 21.1 14.9 26.8 0.0 0.0 9.4 0.2 42.3 28.1 11.1 11.4 19.1 16.2 10.3 4.8 12.8 10.5 20.2 0.0 0.4 0.9 58.1 46.9 2.5 0.4 16.8 18.5 17.1 16.2 8.0 9.9 2.7 0.1 9.5 18.3 29.9 0.0 0.1 10.8 96.4 0.1 21.9 20.0 5.6 32.6 1.8 7.7 1.4 8.7 2.2 28.4 2.8 0.0 3.5 0.0 16.6 27.5 1.7 34.9 18.4 0.3 8.7 46.6 159.0 1.8 3.6 65.7 2.8 59.7 0.2 0.5 28.0 32.5 0.3 1.7 18.7 16.2 21.2 ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 181.5;Endothelial cells: 119.7;Hepatic stellate cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 247.6;TIME: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" 41.4 7.2 11.4 6.6 9.6 0.2 31.8 9.0 9.4 10.0 5.8 6.5 2.9 10.9 2.1 5.5 10.3 9.7 25.8 7.9 9.2 18.5 5.3 34.8 7.8 11.3 10.7 4.1 4.3 4.7 4.6 28.6 11.2 7.0 1.7 0.2 4.1 4.6 13.9 6.9 7.3 9.9 9.5 43.5 6.3 1.4 13.2 1.8 16.7 11.9 2.0 9.4 7.0 8.6 0.4 0.0 0.4 0.0 0.0 1.1 0.1 0.2 3.1 0.7 1.5 0.0 0.0 0.0 23.6 0.1 1.0 0.0 0.0 0.4 1.2 0.0 0.0 0.9 0.0 0.1 0.6 0.0 0.0 0.1 0.0 8.9 3.0 0.4 247.6 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 224.8 1.2 0.6 0.3 1.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 9.6 9.0 9.4 7.9 9.2 11.3 10.7 11.2 9.5 13.2 8.6 181.5 0.0 4.2 2.3 1.6 2.2 1.0 0.2 0.6 0.2 0.6 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.5 0.2 0.3 119.7 0.0 4.0 0.0 0.2 0.0 5.2 0.0 0.3 2.5 0.6 148.9 1.5 0.1 0.0 0.0 0.0 0.0 8.1 3.7 1.7 4.4 2.8 1.8 20.6 0.1 1.1 0.0 0.5 0.1 0.1 0.0 1.2 2.6 0.3 0.0 0.0 0.0 5.2 0.0 4.5 2.1 0.0 0.1 0.6 1.3 0.0 0.9 2.0 0.1 0.2 ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179759-11348330 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 280.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol NA NA 710000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" 36.4 9.3 6.7 13.5 16.3 6.8 22.3 19.1 14.3 18.7 0.8 22.6 16.7 22.0 10.3 16.2 13.6 15.6 17.0 12.1 3.5 14.5 16.5 16.9 10.1 1.7 4.4 19.0 11.7 12.8 5.9 24.9 1.4 17.4 26.2 13.5 14.6 18.1 30.4 8.5 19.2 27.9 2.0 16.4 14.1 7.8 6.4 8.4 13.9 28.9 8.8 21.1 11.0 10.4 17.5 41.7 33.8 33.2 59.7 41.6 21.6 40.4 37.7 25.8 27.1 39.8 37.2 21.9 23.4 64.5 31.3 18.9 24.7 23.4 40.6 31.2 14.7 43.8 70.6 79.7 21.4 24.7 12.1 32.6 14.6 31.9 22.6 21.0 42.0 11.9 38.6 8.6 38.8 14.8 18.2 12.7 18.8 36.9 25.3 21.7 74.2 7.0 14.0 48.8 15.9 16.9 79.6 27.4 27.4 25.5 11.3 13.6 57.3 52.9 38.2 21.2 36.0 6.8 8.9 18.8 22.8 28.2 75.4 0.9 0.4 0.4 0.6 0.4 0.7 0.3 0.4 0.4 0.3 0.5 0.4 0.4 0.6 0.8 0.4 0.6 0.4 0.2 6.7 16.3 19.1 14.3 12.1 3.5 1.7 4.4 1.4 2.0 6.4 10.4 114.5 115.4 79.1 81.3 16.0 39.9 43.0 15.3 21.1 35.7 33.5 41.1 107.0 37.1 53.1 22.0 58.4 26.3 20.4 97.7 1.9 27.1 11.0 53.6 141.2 90.3 21.2 22.5 280.4 39.5 19.1 64.0 18.3 55.3 29.0 36.9 56.0 43.1 19.6 80.8 158.1 92.2 10.2 20.3 27.0 4.9 43.8 30.4 23.2 107.7 20.6 38.4 15.5 99.0 66.9 39.1 43.6 78.6 16.2 53.5 45.3 15.7 32.7 48.5 131.5 70.0 118.5 30.3 24.6 19.9 27.8 31.5 18.5 34.2 54.8 40.7 RPGR "COD1, CORDX1, CRD, RP15, RP3" ENSG00000156313 "Retinitis pigmentosa GTPase regulator" Q92834 X 38269163-38327544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Guanine-nucleotide releasing factor" "Cancer-related genes, Ciliopathy, Cone-rod dystrophy, Deafness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 146.1;Hepatic stellate cells: 121.7;Respiratory ciliated cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 14.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 14.6" "Cell line enhanced" "Detected in many" "HL-60: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001593, HPA073455" Approved Supported "Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "HPA001593: AB_1079835, HPA073455: AB_2686603" "unprognostic (3.22e-2)" "unprognostic (1.16e-2)" "unprognostic (5.04e-2)" "unprognostic (1.08e-1)" "unprognostic (3.20e-1)" "unprognostic (9.94e-2)" "unprognostic (3.46e-2)" "unprognostic (6.32e-2)" "unprognostic (2.04e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-6)" "unprognostic (1.93e-1)" "unprognostic (7.59e-2)" "unprognostic (8.96e-3)" "unprognostic (1.61e-3)" 19.2 5.7 4.7 4.4 4.6 12.2 16.8 5.2 5.5 10.2 15.5 9.1 3.0 11.6 2.5 5.5 15.0 5.5 9.8 4.6 6.3 6.2 3.7 14.8 3.7 7.6 7.0 6.2 7.5 2.6 32.9 3.7 5.8 6.9 3.6 12.1 5.2 2.6 12.1 6.0 9.4 4.5 6.6 5.1 6.8 8.1 5.3 4.7 9.7 3.7 3.2 8.7 8.2 5.4 4.7 6.0 3.4 3.2 3.6 5.2 2.7 5.8 6.5 4.1 4.8 2.7 2.6 7.1 1.8 3.9 3.4 4.4 4.1 1.8 5.6 7.5 7.9 2.5 2.7 5.5 3.3 31.8 5.8 8.0 2.4 8.7 9.2 1.6 18.9 7.5 3.3 0.0 5.7 1.5 9.1 17.7 8.7 2.9 7.5 6.8 11.7 6.4 3.6 3.0 2.7 5.2 6.4 2.6 7.2 5.1 1.7 5.4 22.4 4.5 8.0 10.7 7.2 1.9 3.9 6.0 10.6 6.1 6.2 1.3 2.6 5.9 1.3 2.4 2.9 1.9 1.5 1.8 2.6 1.5 2.2 1.8 14.6 1.7 2.0 1.8 1.9 1.8 4.7 4.6 5.2 5.5 4.6 6.3 7.6 7.0 5.8 6.6 5.3 5.4 75.2 16.0 32.6 21.2 21.8 7.9 13.5 6.6 7.4 29.5 8.8 8.8 8.0 8.6 18.0 1.8 62.6 5.8 14.0 12.6 3.9 15.3 51.4 146.1 30.4 61.3 17.4 5.5 21.8 8.6 9.5 11.8 9.2 21.0 20.3 73.5 121.7 9.7 7.8 35.3 20.0 13.5 10.2 16.2 8.4 9.1 7.8 14.5 5.4 18.7 15.5 9.4 14.4 9.0 17.1 9.9 8.9 4.5 11.0 10.2 5.0 3.1 119.2 85.7 0.0 23.1 12.9 24.9 25.3 4.8 5.8 8.2 17.2 6.6 8.9 11.2 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 236.1;Endothelial cells: 122.3;Hepatic stellate cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 73.0;HUVEC TERT2: 198.9;TIME: 113.3;U-251 MG: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" 114.7 14.4 58.8 29.8 62.7 18.5 91.9 59.8 59.0 18.5 27.8 19.5 9.4 24.7 3.9 26.8 22.9 28.0 71.8 51.3 65.1 18.0 31.3 78.3 46.3 65.2 73.0 8.2 20.3 23.3 8.7 48.1 61.3 13.7 10.1 14.6 15.0 7.8 27.9 17.9 22.3 31.2 57.6 63.1 17.1 2.6 76.5 21.4 35.9 51.5 26.9 34.3 19.2 52.6 15.6 0.2 14.2 0.0 1.4 32.7 0.1 73.0 13.5 47.9 16.6 0.1 0.7 0.0 17.8 25.2 0.4 0.0 1.8 0.8 27.0 6.1 1.2 6.8 0.3 0.0 6.6 0.0 3.5 45.0 0.3 0.1 3.7 1.7 198.9 5.8 0.2 14.4 13.5 0.0 20.6 0.0 3.9 0.4 4.8 0.0 13.4 0.5 0.1 0.0 0.0 0.1 0.7 0.0 0.2 0.9 0.0 0.2 113.3 6.8 2.9 2.0 147.1 1.3 0.0 1.0 0.7 0.0 0.4 1248.4 2.2 55.4 589.4 2.1 441.5 294.7 502.6 492.1 2.6 346.9 383.3 396.3 15.4 397.5 3.4 3.1 329.4 438.7 58.8 62.7 59.8 59.0 51.3 65.1 65.2 73.0 61.3 57.6 76.5 52.6 236.1 0.0 8.9 37.9 36.0 7.6 0.2 0.0 2.2 0.4 1.1 1.1 23.8 2.8 1.3 0.0 0.0 5.9 25.0 0.0 0.0 0.0 0.0 1.1 1.0 122.3 0.0 0.4 0.1 0.0 0.3 11.7 0.5 1.8 7.6 9.7 114.2 8.9 9.9 0.0 0.3 0.0 0.0 6.5 5.7 0.0 0.9 3.0 5.4 13.1 9.9 31.1 40.2 0.5 0.2 0.0 0.0 0.0 18.2 0.5 0.0 0.1 0.0 1.4 0.0 3.6 4.8 0.7 0.7 0.6 5.1 2.6 29.9 1.8 0.1 0.4 SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted intracellular proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.6" "Cell type enhanced" "Detected in many" "Adipocytes: 65.9;Endothelial cells: 51.3;Hepatic stellate cells: 62.4;Langerhans cells: 37.7;Microglial cells: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 12.1;REH: 11.5;TIME: 37.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 2000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA035108: AB_10670289, HPA072936: AB_2686559" "unprognostic (1.94e-1)" "unprognostic (2.84e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (6.39e-2)" 15.2 5.0 1.5 3.1 1.8 0.4 12.7 1.4 3.4 5.6 1.4 5.2 0.0 6.0 0.9 2.7 6.5 2.2 11.8 1.6 1.8 7.5 7.5 16.3 2.1 2.7 1.7 2.6 3.1 0.1 3.8 4.3 2.2 4.6 1.2 0.2 4.2 0.0 5.3 3.1 5.4 1.2 1.7 25.6 4.2 1.6 1.7 0.5 18.8 1.9 1.0 5.6 4.6 2.8 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.3 12.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 11.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 37.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 1.8 1.4 3.4 1.6 1.8 2.7 1.7 2.2 1.7 1.7 2.8 65.9 22.4 17.6 6.5 0.6 3.4 0.4 0.7 1.2 1.2 0.8 0.9 3.5 0.0 2.9 3.7 4.2 0.4 2.0 4.9 1.9 0.4 0.3 0.5 0.9 51.3 0.0 3.4 5.4 0.2 0.2 2.5 4.1 1.1 3.8 0.3 62.4 2.3 9.0 0.0 3.5 4.4 0.0 15.7 37.7 0.4 1.2 10.1 3.6 26.2 4.8 0.7 0.0 0.5 1.1 0.3 1.2 1.2 0.0 0.7 3.0 0.2 3.0 2.0 0.0 2.1 3.0 0.5 0.6 0.3 2.7 1.2 1.0 1.3 2.2 0.8 SCN1B ENSG00000105711 "Sodium voltage-gated channel beta subunit 1" Q07699 19 35030470-35040449 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 256.5;skeletal muscle: 572.0;tongue: 227.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 67.9;Excitatory neurons: 50.4;Hofbauer cells: 31.3;Inhibitory neurons: 48.3;Kupffer cells: 35.1;Macrophages: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 17.5;EFO-21: 12.7;TIME: 26.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 349.1" "Secreted in other tissues" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (8.18e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-2)" "unprognostic (6.40e-2)" "unprognostic (1.17e-2)" "unprognostic (2.69e-2)" "unprognostic (4.40e-2)" "unprognostic (1.20e-1)" "unprognostic (3.34e-2)" "unprognostic (4.72e-3)" "prognostic favorable (1.38e-4)" "unprognostic (2.25e-1)" "unprognostic (2.05e-2)" "unprognostic (9.68e-3)" "unprognostic (5.81e-2)" "unprognostic (4.12e-2)" "unprognostic (4.78e-2)" 20.2 13.6 48.2 3.3 53.0 2.3 16.3 95.8 256.5 15.5 7.7 9.7 1.9 9.4 2.2 8.6 21.7 4.8 95.4 45.0 97.2 8.3 8.5 11.1 3.0 120.4 67.0 7.8 12.3 18.2 17.4 5.3 115.7 8.7 2.7 10.7 15.4 3.6 572.0 6.3 8.0 4.5 52.2 19.8 8.4 2.8 153.5 1.3 11.1 227.8 0.8 13.4 10.5 113.6 0.4 17.5 0.2 1.0 5.2 7.8 0.1 7.1 6.1 3.4 0.9 0.7 0.2 0.2 12.7 7.1 3.0 0.3 1.1 0.7 1.6 0.2 0.8 0.2 2.5 4.5 6.9 0.1 0.1 2.5 0.1 0.4 0.2 6.8 11.6 0.2 0.4 0.1 2.2 1.7 0.2 0.2 0.8 1.6 5.1 0.9 1.8 0.2 0.5 0.1 8.1 4.3 0.9 0.1 1.4 0.6 1.6 0.4 26.1 6.7 6.6 0.3 4.6 0.3 0.5 1.0 4.0 0.8 4.8 0.7 0.2 0.1 0.3 0.1 0.6 0.1 0.1 0.1 0.6 0.2 0.1 0.1 0.7 0.2 0.1 0.1 0.3 0.7 48.2 53.0 95.8 256.5 45.0 97.2 120.4 67.0 115.7 52.2 153.5 113.6 12.8 0.0 3.3 11.8 1.1 1.8 0.8 1.6 0.0 67.9 1.6 7.7 20.3 0.0 0.6 0.0 2.1 0.4 2.9 0.0 9.8 0.3 0.3 2.0 2.0 9.7 0.0 0.4 50.4 2.6 0.6 9.9 2.0 1.8 2.5 0.1 20.7 1.2 31.3 8.4 48.3 1.6 0.0 35.1 3.7 0.0 7.5 29.5 3.6 15.9 3.0 13.3 0.0 6.0 18.5 0.7 0.1 2.2 2.7 1.1 0.1 2.5 1.0 22.8 0.0 25.3 3.6 0.2 0.7 0.1 1.1 1.0 2.0 0.1 0.8 0.3 SEC14L1 "PRELID4A, SEC14L" ENSG00000129657 "SEC14 like lipid binding 1" Q92503 17 77088749-77217101 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 430.3;Hepatic stellate cells: 286.3;Late spermatids: 740.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 355.0" "Lineage enriched" "Detected in all" 11 "granulocytes: 355.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 398.1;TIME: 251.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021463, HPA028703" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA021463: AB_2670712, HPA028703: AB_10602300" "unprognostic (1.19e-1)" "unprognostic (8.61e-2)" "unprognostic (1.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (7.37e-2)" "unprognostic (1.21e-1)" "unprognostic (7.40e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (1.37e-1)" "unprognostic (1.33e-3)" "unprognostic (3.09e-1)" "unprognostic (4.30e-2)" 66.7 54.2 42.6 44.6 63.3 65.5 57.6 75.4 60.7 39.5 36.3 19.5 21.8 24.6 28.2 31.5 27.3 34.3 50.2 49.5 57.5 42.0 25.3 66.9 49.7 64.0 63.0 20.7 30.8 25.1 27.9 76.7 54.6 18.3 19.8 19.0 35.0 16.8 94.1 20.5 21.7 27.1 46.2 49.9 31.7 51.9 63.6 24.1 41.6 54.7 46.2 26.0 20.6 50.9 55.0 45.4 65.6 105.0 27.4 36.3 24.1 47.4 42.0 57.8 49.5 55.7 39.6 143.1 93.3 65.0 71.1 26.3 36.0 47.8 72.6 27.3 50.1 81.1 42.4 75.9 44.4 26.8 39.8 46.6 20.7 47.8 47.8 69.1 398.1 24.3 55.8 136.0 79.2 36.2 28.5 22.4 25.0 25.7 43.7 20.3 104.2 112.2 91.2 26.2 59.5 44.8 51.1 31.3 32.1 58.3 27.9 20.7 251.1 65.4 60.6 35.0 37.7 71.1 64.8 79.9 27.9 22.1 21.6 33.8 19.4 48.9 7.1 28.3 8.9 14.6 6.9 5.3 12.7 10.8 10.9 5.9 355.0 10.0 33.3 18.9 12.5 11.5 42.6 63.3 75.4 60.7 49.5 57.5 64.0 63.0 54.6 46.2 63.6 50.9 430.3 41.7 18.6 55.8 69.4 29.3 23.5 22.5 37.0 31.5 86.5 37.8 17.6 15.7 28.9 27.6 18.8 10.8 77.5 20.3 99.7 18.0 242.6 114.8 46.7 205.9 19.7 86.5 33.0 20.7 10.8 34.0 35.2 240.5 34.7 104.3 286.3 11.1 51.6 37.0 54.6 14.0 61.1 127.2 48.1 740.3 26.4 115.1 35.6 62.8 76.1 31.4 34.0 23.1 44.4 41.8 15.2 17.3 269.1 39.5 9.6 24.8 69.5 17.2 39.5 36.4 36.3 45.1 42.5 25.1 30.4 13.3 51.6 64.3 11.5 39.1 SELE "CD62E, ELAM, ELAM1, ESEL" ENSG00000007908 "Selectin E" P16581 1 169722640-169764705 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 56.1" "Cell type enriched" "Detected in some" 4 "Endothelial cells: 379.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HUVEC TERT2: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" CAB002143 Enhanced NA NA 8140000 180000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002143: AB_563608" "unprognostic (2.39e-1)" "unprognostic (2.16e-2)" "unprognostic (1.37e-2)" "unprognostic (2.09e-2)" "unprognostic (1.61e-1)" "unprognostic (1.40e-2)" "unprognostic (1.59e-1)" "unprognostic (2.94e-1)" "unprognostic (3.63e-1)" "unprognostic (3.88e-1)" "unprognostic (9.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.56e-2)" "unprognostic (8.13e-3)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.55e-1)" 29.6 5.5 1.2 12.6 0.8 0.5 12.0 0.5 1.7 4.1 4.1 4.2 0.7 5.3 0.5 4.0 23.8 10.7 8.0 0.8 1.6 7.6 6.9 10.3 3.0 1.8 1.2 3.3 1.2 12.5 4.0 1.4 1.7 27.7 2.6 0.3 3.1 3.8 0.8 5.5 2.3 18.7 1.3 0.0 5.2 2.4 2.9 8.4 13.8 1.0 3.6 56.1 5.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.5 1.7 0.8 1.6 1.8 1.2 1.7 1.3 2.9 1.1 34.6 0.0 3.8 0.0 0.0 46.1 1.1 0.0 1.2 0.0 0.5 0.3 4.0 1.5 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.2 0.3 379.5 0.0 0.0 0.1 0.0 0.0 12.7 0.0 0.2 1.3 0.0 3.9 8.5 0.0 0.0 0.0 0.0 0.0 0.0 81.9 3.0 0.0 0.9 46.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 1.3 4.1 0.2 0.0 1.2 47.7 0.0 3.4 0.1 0.1 2.5 SELENOW "SELW, SEPW1" ENSG00000178980 "Selenoprotein W" P63302 19 47778585-47784686 "Predicted intracellular proteins" Antioxidant "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1609.8;skeletal muscle: 1723.7;tongue: 1969.8" "Cell type enhanced" "Detected in many" "Adipocytes: 855.4;Breast myoepithelial cells: 490.5;Distal tubular cells: 633.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 541.5;HUVEC TERT2: 624.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.03e-1)" "unprognostic (8.98e-3)" "unprognostic (7.21e-2)" "unprognostic (2.98e-2)" "unprognostic (6.28e-2)" "unprognostic (4.17e-2)" "unprognostic (4.46e-3)" "prognostic favorable (5.44e-4)" "unprognostic (1.73e-1)" "unprognostic (2.42e-1)" "unprognostic (1.36e-1)" "unprognostic (6.78e-2)" "unprognostic (1.45e-3)" "unprognostic (4.58e-2)" "unprognostic (1.36e-1)" "unprognostic (3.46e-2)" "unprognostic (3.27e-1)" 188.5 103.4 1283.6 107.6 1308.6 44.7 204.0 1297.0 1609.8 270.1 1374.7 535.1 127.4 218.5 258.8 266.6 306.9 240.5 988.8 1351.6 1261.2 146.6 109.6 199.7 112.1 1273.2 1296.9 170.9 132.6 168.7 138.6 153.5 1251.5 233.2 224.7 128.1 195.8 291.5 1723.7 312.3 177.5 467.0 1278.9 146.1 207.8 55.3 1333.8 113.7 156.7 1969.8 87.8 323.5 173.3 1321.9 74.4 119.6 174.0 141.4 124.7 268.1 43.7 76.7 59.6 71.4 53.8 49.6 57.1 0.0 64.3 163.1 70.1 57.8 293.6 389.6 124.1 216.4 72.9 34.9 61.7 63.2 138.0 9.1 131.8 285.1 541.5 119.4 113.0 158.7 624.7 109.1 46.4 28.6 317.7 179.0 156.6 115.4 68.0 186.0 91.4 26.9 18.3 23.5 208.0 130.8 72.4 51.5 77.6 203.0 77.9 299.2 114.2 43.7 213.9 71.0 151.2 50.7 141.3 46.3 153.1 16.1 75.3 93.2 165.0 309.3 187.8 448.3 303.8 226.2 265.1 182.4 333.6 311.7 147.8 159.2 331.0 288.3 19.9 216.1 293.5 166.8 436.6 414.1 1283.6 1308.6 1297.0 1609.8 1351.6 1261.2 1273.2 1296.9 1251.5 1278.9 1333.8 1321.9 855.4 333.3 282.3 0.0 20.4 0.0 0.0 0.0 0.0 0.0 347.1 490.5 0.0 0.0 219.7 154.5 0.0 157.0 127.3 0.0 633.9 278.3 0.0 350.2 221.5 220.8 0.0 0.0 0.0 244.5 327.9 145.5 0.0 188.4 119.8 153.8 0.0 0.0 251.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.3 0.0 0.0 156.6 0.0 0.0 0.0 0.0 243.7 0.0 0.0 21.3 0.0 0.0 380.8 303.9 0.0 0.0 0.0 210.7 0.0 0.0 0.0 0.0 182.4 66.9 341.7 0.0 0.0 SEMA3D "coll-2, Sema-Z2" ENSG00000153993 "Semaphorin 3D" O95025 7 84995553-85186855 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 47.8;thyroid gland: 45.4" "Cell type enhanced" "Detected in many" "Early spermatids: 157.4;Leydig cells: 52.5;Peritubular cells: 62.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 28.4;HaCaT: 28.7;TIME: 44.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037522 Uncertain Approved "Golgi apparatus,Plasma membrane" "Secreted in other tissues" NA NA 120000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus" "Plasma membrane" "HPA037522: AB_10672494" "unprognostic (7.05e-2)" "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (7.58e-3)" "unprognostic (4.02e-3)" "unprognostic (9.94e-2)" "unprognostic (5.62e-2)" "unprognostic (1.63e-1)" "unprognostic (9.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.26e-3)" "unprognostic (1.63e-1)" "unprognostic (2.75e-3)" "unprognostic (5.25e-3)" 3.2 2.9 5.9 1.0 1.9 0.0 5.9 0.8 4.6 5.6 0.0 2.8 1.8 2.4 2.6 1.7 5.1 1.7 2.2 6.2 4.7 3.8 1.0 3.6 3.3 2.3 8.9 1.9 0.7 0.2 0.5 0.7 2.2 8.3 3.4 2.2 4.3 1.9 0.0 2.4 3.3 1.4 3.0 47.8 3.3 3.8 3.2 0.3 45.4 0.9 1.4 3.1 0.7 3.2 0.0 0.0 12.1 0.0 0.0 0.0 0.5 7.6 8.2 8.8 4.2 0.0 0.0 0.0 2.2 28.4 0.2 28.7 3.1 0.0 5.8 0.0 5.8 0.0 3.1 0.0 0.1 0.0 0.0 0.1 0.0 1.5 7.2 10.1 13.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.6 7.5 2.1 8.9 6.8 2.8 0.0 0.1 1.1 0.0 0.0 0.4 13.8 0.4 0.0 44.2 0.0 2.7 0.4 0.0 5.4 3.4 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 1.9 0.8 4.6 6.2 4.7 2.3 8.9 2.2 3.0 3.2 3.2 2.8 0.0 3.3 18.3 1.8 3.6 2.4 0.1 0.0 2.6 0.8 8.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 157.4 1.6 0.3 14.8 26.5 0.0 12.3 0.2 0.0 15.3 0.0 4.3 2.5 0.2 2.9 0.0 1.3 1.7 5.1 0.7 2.0 0.0 5.7 23.3 52.5 0.5 12.4 19.7 0.0 1.9 0.0 3.0 0.9 0.0 0.0 62.4 0.0 5.8 1.9 4.7 0.8 4.1 0.0 0.7 2.0 0.7 0.8 0.1 2.4 0.0 0.5 11.2 1.0 0.4 SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 100.8" "Cell type enhanced" "Detected in many" "Adipocytes: 40.2;Bipolar cells: 23.4;Endothelial cells: 24.4;Hepatic stellate cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 108.1;HUVEC TERT2: 187.0;RT4: 112.3;SK-BR-3: 170.2;TIME: 338.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" NA NA 1700000 7900000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA035008: AB_10604091" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (1.87e-2)" "unprognostic (5.52e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.71e-1)" "unprognostic (9.05e-2)" "unprognostic (4.20e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.23e-2)" "unprognostic (6.19e-2)" "unprognostic (8.56e-2)" "unprognostic (3.88e-3)" "unprognostic (6.87e-3)" 33.8 9.0 8.8 8.6 5.7 2.7 31.9 5.1 8.1 28.3 12.0 10.5 13.4 14.5 5.4 100.8 15.6 10.8 22.6 5.0 9.2 49.2 4.8 46.2 3.7 10.2 12.7 3.6 6.7 5.5 11.1 30.4 8.7 32.7 6.3 22.0 24.6 32.5 10.4 75.1 12.5 9.1 6.3 50.7 17.3 2.4 21.8 6.1 27.1 6.1 12.6 27.0 55.4 4.7 13.9 3.1 0.7 14.2 0.2 1.3 3.0 8.0 24.2 6.5 10.2 5.4 6.1 0.5 77.9 1.1 0.7 47.5 6.9 100.7 2.4 0.1 1.8 0.8 108.1 18.5 5.7 1.7 3.2 6.2 55.3 15.1 45.4 90.7 187.0 1.2 2.9 0.1 1.3 12.4 1.5 7.5 8.6 6.2 10.1 11.8 0.0 0.5 7.2 112.3 1.1 2.6 12.8 170.2 0.3 10.4 67.2 7.3 338.6 4.2 31.9 29.7 5.5 0.2 0.0 0.9 0.3 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 5.7 5.1 8.1 5.0 9.2 10.2 12.7 8.7 6.3 21.8 4.7 40.2 0.0 1.1 0.0 0.2 6.8 3.0 9.2 5.7 23.4 10.7 6.0 9.2 1.5 6.6 18.4 10.4 11.2 0.6 5.5 0.0 0.3 0.0 6.5 2.4 24.4 0.0 0.0 0.7 0.8 0.5 1.1 16.3 6.9 0.0 0.2 25.4 0.6 1.4 6.7 1.1 10.7 0.0 0.3 0.8 0.3 0.3 0.2 0.0 3.7 0.0 8.7 0.0 0.0 0.1 6.8 3.8 0.0 0.0 2.5 5.7 0.7 5.4 19.8 0.0 0.5 2.5 0.0 0.4 17.7 8.9 6.3 0.4 0.2 5.2 8.6 SEMA6C KIAA1869 ENSG00000143434 "Semaphorin 6C" Q9H3T2 1 151131685-151146664 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 322.9;tongue: 96.9" "Cell type enhanced" "Detected in many" "Adipocytes: 12.9;Cardiomyocytes: 19.1;Cone photoreceptor cells: 20.9;Inhibitory neurons: 13.7;Skeletal myocytes: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.1;HUVEC TERT2: 24.8;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA076150, HPA077625" Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1500000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "Nucleoli fibrillar center, Cytosol" "HPA076150: , HPA077625: " "unprognostic (6.97e-2)" "unprognostic (8.40e-2)" "unprognostic (1.56e-3)" "prognostic unfavorable (3.27e-4)" "unprognostic (2.79e-1)" "unprognostic (2.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" "unprognostic (4.25e-2)" "prognostic favorable (3.06e-5)" "unprognostic (3.72e-2)" "unprognostic (1.67e-2)" "unprognostic (6.12e-2)" "unprognostic (9.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" 8.8 2.8 7.7 1.8 6.7 1.2 7.9 21.9 9.4 12.0 1.0 7.6 13.7 10.5 1.4 5.5 10.7 3.7 38.8 7.9 5.4 12.1 12.4 5.1 1.7 5.0 5.0 14.8 3.6 2.1 13.4 1.9 4.9 8.3 1.8 5.2 8.5 2.3 322.9 8.9 10.8 6.2 2.2 3.0 5.4 32.2 7.3 2.2 4.7 96.9 0.9 8.4 8.8 5.3 0.9 1.0 14.1 5.4 5.8 1.9 1.3 1.0 0.5 0.9 1.3 0.3 0.6 0.7 4.0 3.3 2.0 1.4 1.3 0.5 0.8 1.3 4.2 7.7 0.7 1.2 0.8 0.1 2.7 3.3 1.7 1.2 0.6 2.8 24.8 4.1 0.7 0.7 2.3 0.5 1.3 1.0 6.3 0.2 1.7 9.0 3.1 0.3 0.5 0.4 7.1 9.3 1.3 0.6 1.2 3.5 1.6 1.3 11.8 2.3 3.3 3.5 0.6 5.9 1.2 6.1 0.6 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 6.7 21.9 9.4 7.9 5.4 5.0 5.0 4.9 2.2 7.3 5.3 12.9 0.0 2.8 3.9 1.0 1.7 0.8 0.3 0.6 5.7 1.9 3.0 19.1 1.5 0.8 0.0 20.9 0.2 0.6 0.1 0.0 0.3 0.6 0.4 2.8 10.2 0.0 0.8 6.7 0.4 0.6 4.4 0.5 0.4 0.0 9.9 6.8 5.3 0.4 6.7 13.7 0.3 0.0 2.5 0.7 3.1 5.6 0.5 1.8 4.7 0.4 1.9 1.0 5.5 1.5 0.4 0.0 2.6 1.9 0.5 3.3 2.9 0.3 7.5 0.0 12.0 2.9 3.3 1.2 0.5 1.0 0.1 0.8 0.5 0.8 0.5 SERPINE1 "PAI, PAI1, PLANH1" ENSG00000106366 "Serpin family E member 1" P05121 7 101127104-101139247 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 418.0" "Cell type enhanced" "Detected in many" "Endothelial cells: 165.1;Fibroblasts: 162.1;Pancreatic endocrine cells: 231.8;Smooth muscle cells: 239.3;Syncytiotrophoblasts: 651.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "NK-cell: 9.5" "Lineage enriched" "Detected in single" 20 "NK-cells: 9.5" "Cell line enhanced" "Detected in many" "BJ: 3483.8;HUVEC TERT2: 4014.7;LHCN-M2: 3874.5;TIME: 10032.6;U-138 MG: 4609.6;U-251 MG: 4256.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA050039, CAB068501" Uncertain Approved Cytosol "Secreted to blood" No No 142000000 13000000 "Cluster 22: NK-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB068501: AB_1642775, HPA050039: AB_2680997" "unprognostic (5.02e-2)" "prognostic unfavorable (5.01e-4)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.10e-2)" "unprognostic (9.04e-3)" "prognostic unfavorable (2.84e-5)" "unprognostic (6.80e-3)" "prognostic unfavorable (4.41e-6)" "unprognostic (2.33e-1)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.88e-8)" "prognostic unfavorable (3.27e-6)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (5.51e-4)" 215.5 75.3 3.1 91.6 3.4 1.7 56.2 5.2 12.8 62.1 5.0 31.7 7.4 31.1 1.0 16.4 41.3 360.3 136.0 3.9 6.6 166.2 345.8 260.2 21.3 6.4 3.7 105.6 135.1 11.8 12.3 418.0 4.5 37.8 5.4 4.9 10.6 8.0 17.8 21.2 13.1 74.3 4.8 13.8 30.3 5.5 12.7 6.7 59.5 4.3 3.5 359.9 19.2 6.0 77.3 64.4 1.2 5.1 766.6 1511.0 89.3 3483.8 654.6 1717.6 1487.4 9.4 5.5 2.7 812.6 1117.9 2367.3 18.1 0.4 269.4 1756.2 4.3 0.7 1.1 5.2 61.4 1532.6 0.2 3.8 596.1 106.9 2641.4 1374.8 928.5 4014.7 0.2 6.4 2.5 3874.5 0.4 0.6 2.2 18.2 1.3 41.7 0.6 6.1 4.8 5.1 30.3 1.0 0.8 286.3 77.2 8.3 410.9 3.3 9.9 10032.6 4609.6 204.0 1593.8 4256.0 0.6 2.9 4.2 1150.5 2.4 45.9 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 9.5 0.0 0.3 0.0 0.8 3.1 3.4 5.2 12.8 3.9 6.6 6.4 3.7 4.5 4.8 12.7 6.0 35.8 0.0 7.7 0.0 1.1 40.0 43.7 97.4 14.2 0.3 0.3 2.3 2.5 4.3 11.0 5.5 0.0 56.0 1.0 0.4 0.0 65.1 0.0 4.7 53.8 165.1 5.3 0.0 0.5 4.5 75.1 162.1 0.5 3.2 10.2 12.4 40.4 112.3 15.9 0.0 0.3 0.2 8.2 4.6 9.6 1.1 17.7 11.1 7.2 5.6 1.1 0.7 0.0 0.0 0.0 231.8 0.0 12.0 3.6 9.7 0.1 0.0 8.2 0.3 39.5 55.4 239.3 0.0 0.1 9.0 24.7 651.7 2.3 2.1 0.5 8.1 SGMS2 "MGC26963, SMS2" ENSG00000164023 "Sphingomyelin synthase 2" Q8NHU3 4 107824563-107915047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 126.6;Basal prostatic cells: 167.4;Endometrial ciliated cells: 172.1;Glandular and luminal cells: 147.8;Urothelial cells: 159.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 3.7;eosinophil: 2.4;intermediate monocyte: 1.5;myeloid DC: 4.2;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 35 "dendritic cells: 4.2;granulocytes: 2.4;monocytes: 3.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015076 Supported NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA015076: AB_1857298" "unprognostic (7.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.36e-2)" "unprognostic (1.87e-2)" "unprognostic (7.88e-3)" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (1.32e-1)" "unprognostic (4.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.82e-3)" "unprognostic (3.26e-1)" "prognostic favorable (1.37e-4)" "unprognostic (6.18e-2)" "unprognostic (5.63e-2)" "unprognostic (8.71e-2)" "unprognostic (5.22e-3)" 8.6 3.0 5.2 9.0 15.3 4.6 5.2 10.1 7.8 12.7 36.7 12.3 19.5 8.8 4.6 16.4 12.5 39.6 9.1 3.3 6.5 14.5 20.4 27.8 1.1 13.9 14.3 1.1 11.7 3.6 4.7 5.1 13.0 9.6 10.6 0.8 9.2 4.6 2.5 3.6 16.5 29.1 10.2 1.1 13.8 9.6 10.6 0.8 18.0 3.4 2.9 13.9 4.2 21.6 20.8 7.7 1.1 5.8 12.9 29.9 0.4 25.0 18.8 11.6 12.1 3.5 42.1 1.5 9.7 40.0 10.1 7.6 14.5 22.1 20.7 5.9 5.7 0.9 16.5 1.2 14.8 14.2 0.1 10.4 15.1 22.7 27.4 24.2 26.1 0.3 0.2 0.5 18.6 6.9 0.5 0.1 0.7 12.1 8.6 0.5 9.9 2.9 30.7 10.0 2.0 0.1 19.1 26.9 3.3 3.0 14.5 0.4 44.7 13.9 21.9 20.1 11.7 1.4 0.5 0.8 18.7 3.4 5.9 0.0 3.7 2.4 0.0 1.5 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.3 0.0 1.4 0.0 0.0 1.0 5.2 15.3 10.1 7.8 3.3 6.5 13.9 14.3 13.0 10.2 10.6 21.6 3.4 86.6 126.6 7.2 1.0 56.0 167.4 12.8 18.2 0.5 20.9 10.4 17.8 28.6 88.0 16.5 0.0 1.0 2.9 32.3 3.9 19.8 71.4 172.1 13.5 10.7 8.9 0.0 8.0 19.5 0.9 26.6 58.1 147.8 10.1 2.8 11.4 25.0 5.5 1.7 10.0 26.0 14.2 22.1 43.0 11.1 2.5 28.2 8.8 1.9 23.3 0.2 2.1 0.5 18.5 37.9 60.5 0.4 0.4 96.9 33.5 12.4 104.0 0.1 0.0 46.1 22.0 0.9 3.1 38.1 72.9 13.8 3.3 0.1 21.8 159.7 SH2D3C NSP3 ENSG00000095370 "SH2 domain containing 3C" Q8N5H7 9 127738317-127778710 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 52.6;dendritic cells: 29.7;Endothelial cells: 52.2;Hepatic stellate cells: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 53.3;HUVEC TERT2: 60.0;REH: 60.7;RPMI-8226: 46.1;TIME: 50.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047586 Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA047586: AB_2680093" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (3.28e-2)" "prognostic favorable (9.47e-4)" "unprognostic (5.23e-2)" "prognostic favorable (1.98e-4)" "unprognostic (3.75e-2)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.58e-3)" "unprognostic (1.61e-1)" "unprognostic (1.88e-3)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (5.28e-2)" 27.3 7.6 11.2 15.9 10.5 11.2 24.9 11.7 13.2 12.2 2.8 7.6 4.5 15.8 1.2 5.8 12.6 9.2 44.7 10.7 9.6 19.9 4.7 52.2 25.8 8.6 7.5 5.0 4.8 3.9 7.1 15.8 8.4 8.5 1.8 0.8 6.8 3.5 14.6 7.4 15.1 7.3 8.1 47.2 7.3 5.1 8.9 27.8 22.9 11.4 10.5 10.9 9.4 8.0 0.1 0.2 0.9 0.2 0.8 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 19.5 1.1 0.0 1.1 0.7 0.0 0.0 0.0 15.6 0.3 7.3 0.1 0.0 0.3 5.6 53.3 0.3 0.2 0.3 0.1 0.0 60.0 11.6 0.2 20.6 0.0 0.1 5.1 16.8 0.8 0.0 0.0 60.7 0.9 46.1 0.0 0.0 14.5 4.4 0.3 0.1 0.0 1.4 0.1 9.6 50.1 0.0 1.2 0.1 0.1 20.3 22.2 20.3 0.4 4.8 0.0 34.0 29.9 37.8 32.3 94.7 26.4 26.2 18.8 30.4 32.8 29.5 16.6 17.5 82.2 34.6 124.8 59.8 21.6 34.2 11.2 10.5 11.7 13.2 10.7 9.6 8.6 7.5 8.4 8.1 8.9 8.0 52.6 3.2 5.8 0.7 15.9 1.3 0.3 1.9 0.6 3.2 1.1 1.7 10.5 2.8 0.9 0.0 0.0 0.3 29.7 0.0 0.0 0.5 13.8 2.2 2.8 52.2 4.2 3.6 10.8 0.0 0.2 3.1 2.0 0.8 11.4 0.0 41.7 0.7 6.0 3.3 10.7 0.3 0.0 6.0 3.7 16.3 1.2 10.7 1.8 23.4 13.4 3.6 21.6 3.0 0.7 0.1 0.0 0.7 7.6 0.1 0.0 0.1 0.8 2.4 6.6 1.2 12.5 1.8 1.5 0.9 0.4 0.7 15.5 2.0 0.1 0.2 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHE ENSG00000169291 "Src homology 2 domain containing E" Q5VZ18 1 154469772-154502412 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.9;Alveolar cells type 2: 23.4;Endothelial cells: 64.4;Hepatic stellate cells: 85.3;Kupffer cells: 26.7;Late spermatids: 23.0;Microglial cells: 26.2;Spermatocytes: 30.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 49.1;TIME: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037417 Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA037417: AB_10672384" "unprognostic (3.24e-1)" "unprognostic (4.95e-2)" "unprognostic (7.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (6.80e-3)" "unprognostic (7.24e-2)" "unprognostic (3.07e-3)" "unprognostic (3.10e-2)" "unprognostic (8.22e-2)" "unprognostic (4.04e-2)" "unprognostic (8.29e-2)" "unprognostic (2.40e-2)" "unprognostic (7.31e-2)" "unprognostic (1.62e-1)" "unprognostic (3.33e-3)" "unprognostic (1.33e-2)" 23.4 9.8 9.4 3.3 8.8 1.2 20.9 7.7 10.6 13.2 7.4 7.4 3.4 12.1 4.3 5.0 12.5 6.9 22.7 8.3 8.3 10.5 5.8 20.6 3.9 8.4 9.1 7.6 3.0 4.9 3.7 16.5 8.8 8.1 4.2 0.6 5.4 4.2 7.1 6.4 8.9 8.0 8.1 21.4 5.5 22.2 10.2 2.6 22.1 11.3 2.3 9.7 9.9 8.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 4.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 49.1 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.5 0.0 1.0 13.6 0.0 0.3 1.4 0.0 0.1 0.2 0.1 0.0 1.0 0.0 0.5 0.3 0.2 1.5 1.5 1.1 0.9 0.6 0.6 0.1 0.9 0.8 0.9 2.4 1.7 1.1 4.0 0.0 0.5 9.4 8.8 7.7 10.6 8.3 8.3 8.4 9.1 8.8 8.1 10.2 8.0 56.9 0.0 23.4 3.9 0.3 3.3 0.4 0.3 1.2 0.1 0.4 1.3 4.4 1.5 1.3 1.8 0.0 0.0 0.2 0.0 0.0 0.1 13.0 0.4 0.3 64.4 0.0 2.7 0.3 0.0 0.0 6.7 0.0 0.5 3.8 2.1 85.3 3.4 1.4 0.0 0.3 0.0 0.0 26.7 6.6 23.0 1.5 2.0 0.0 26.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 3.7 0.7 0.0 0.1 0.0 0.4 0.0 3.3 2.2 30.6 13.0 0.3 1.6 0.1 0.7 0.3 0.0 0.3 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SKIL "SNO, SnoA, SnoN" ENSG00000136603 "SKI like proto-oncogene" P12757 3 170357678-170396835 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008472, HPA014233" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA008472: AB_1856933, HPA014233: " "unprognostic (5.50e-2)" "unprognostic (1.71e-2)" "unprognostic (3.95e-2)" "unprognostic (3.51e-3)" "unprognostic (7.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.21e-2)" "unprognostic (1.68e-2)" "unprognostic (2.52e-2)" "unprognostic (7.79e-2)" "unprognostic (2.26e-3)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.19e-7)" "unprognostic (2.94e-2)" "unprognostic (7.34e-2)" "unprognostic (8.73e-2)" "unprognostic (3.34e-1)" 11.9 12.0 6.1 18.8 7.3 23.1 9.0 8.5 10.0 9.4 8.3 10.4 13.8 12.0 8.2 9.2 6.4 21.1 12.0 6.6 10.9 10.3 15.6 16.1 13.8 10.7 10.8 9.2 9.6 5.7 11.0 13.9 10.5 11.6 9.7 9.6 7.4 8.9 11.0 5.8 14.2 10.5 12.0 7.2 15.9 13.0 11.4 9.2 11.3 21.4 18.4 14.6 8.8 13.2 19.9 24.0 15.6 10.4 20.0 8.7 29.1 19.6 13.6 13.8 10.6 4.9 42.2 24.9 60.5 18.2 23.1 44.8 9.9 9.0 21.3 43.6 9.2 32.8 24.8 11.0 17.8 13.7 17.4 15.3 8.8 19.9 15.0 42.9 34.1 2.4 14.7 27.9 28.4 21.3 5.9 4.5 61.2 21.8 8.1 13.6 52.8 5.0 20.8 31.7 11.5 14.1 48.3 47.4 10.3 31.6 32.2 14.2 66.1 38.2 35.9 33.0 37.1 36.2 18.6 47.3 14.3 7.1 18.3 3.1 3.4 1.8 1.3 8.3 1.8 3.6 1.1 1.7 2.4 4.4 1.9 2.0 4.0 2.8 10.3 1.6 0.5 1.9 6.1 7.3 8.5 10.0 6.6 10.9 10.7 10.8 10.5 12.0 11.4 13.2 104.1 73.7 72.8 21.2 142.1 72.7 88.8 52.5 67.7 25.6 79.3 38.1 12.4 21.5 70.4 35.0 54.2 14.8 124.9 45.9 15.6 56.7 115.7 118.4 80.9 86.0 23.8 3.0 48.6 111.4 58.3 100.6 93.8 102.0 204.8 46.3 72.5 32.0 26.3 53.8 21.6 62.4 22.4 65.4 85.2 35.8 37.9 121.7 35.6 60.0 42.1 12.7 14.4 26.2 27.5 176.5 29.1 68.1 104.3 43.5 41.3 45.9 82.1 30.5 26.3 143.6 63.6 53.9 37.6 61.3 96.0 41.2 81.5 17.5 31.3 117.8 SLC29A1 ENT1 ENSG00000112759 "Solute carrier family 29 member 1 (Augustine blood group)" Q99808 6 44219553-44234142 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 216.6;Extravillous trophoblasts: 224.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 26 "eosinophil: 1046.6" "Lineage enriched" "Detected in all" 26 "granulocytes: 1046.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012384 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA012384: AB_1857073" "unprognostic (1.82e-2)" "unprognostic (1.41e-2)" "unprognostic (1.81e-1)" "unprognostic (2.49e-3)" "unprognostic (2.76e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.96e-4)" "unprognostic (1.38e-2)" "unprognostic (4.60e-2)" "unprognostic (9.02e-2)" "unprognostic (1.34e-1)" 76.4 95.8 10.2 22.3 10.2 53.4 50.4 13.0 14.8 25.4 4.5 59.7 13.1 37.3 15.9 25.3 34.5 44.2 119.7 10.1 12.2 17.8 57.9 33.1 25.9 13.2 10.2 12.9 91.2 22.8 22.6 58.8 15.3 16.5 17.8 21.1 35.6 19.3 144.5 53.0 17.2 46.2 9.5 14.5 53.7 14.9 10.7 81.3 30.7 100.7 17.0 32.8 17.7 10.8 85.3 84.2 58.5 95.1 87.8 8.1 347.1 61.2 24.0 83.6 57.4 91.8 34.8 171.2 60.8 18.5 51.7 103.8 105.2 72.8 51.9 97.6 97.2 150.5 57.8 122.5 14.1 170.3 139.7 10.9 18.4 123.0 42.7 171.6 216.0 137.2 205.4 100.1 46.9 94.0 142.0 114.4 89.0 218.4 55.4 94.0 117.8 208.9 49.1 49.5 75.0 97.0 18.4 58.9 43.9 61.5 80.7 107.1 333.1 46.4 74.8 62.6 117.7 67.0 93.8 221.9 28.8 136.8 57.1 21.9 12.1 1046.6 5.1 38.8 4.2 4.4 2.7 3.9 6.8 2.4 1.1 2.4 1.8 3.1 32.5 40.0 8.2 6.6 10.2 10.2 13.0 14.8 10.1 12.2 13.2 10.2 15.3 9.5 10.7 10.8 64.2 0.0 10.5 1.3 4.0 10.7 9.0 4.1 2.2 10.9 20.2 30.1 46.4 17.2 6.0 7.3 14.6 216.6 5.7 3.0 3.9 24.2 0.5 4.3 3.5 31.7 31.2 49.2 18.4 56.7 224.6 40.0 26.5 11.2 8.2 25.4 25.7 16.7 63.6 5.0 25.4 2.9 79.3 37.0 13.3 2.8 32.9 19.2 35.6 16.9 8.3 4.3 0.0 5.0 2.6 61.9 3.4 53.8 14.2 18.2 0.7 0.9 6.9 11.9 92.1 21.0 22.5 0.4 11.0 4.6 15.6 42.0 3.2 4.1 6.2 9.8 SLC35F2 FLJ13018 ENSG00000110660 "Solute carrier family 35 member F2" Q8IXU6 11 107790991-107928293 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 37.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.0;Basal prostatic cells: 34.5;Suprabasal keratinocytes: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 188.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048185, HPA060150" Enhanced Approved "Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA048185: AB_2680304, HPA060150: " "unprognostic (7.73e-2)" "unprognostic (3.28e-3)" "unprognostic (8.37e-3)" "unprognostic (5.77e-2)" "unprognostic (1.38e-3)" "unprognostic (3.07e-2)" "unprognostic (7.26e-2)" "prognostic unfavorable (4.03e-4)" "unprognostic (6.22e-2)" "unprognostic (8.20e-2)" "prognostic unfavorable (5.92e-6)" "unprognostic (1.24e-1)" "unprognostic (4.10e-2)" "unprognostic (1.34e-1)" "unprognostic (7.33e-2)" "unprognostic (3.25e-2)" "unprognostic (1.19e-1)" 4.1 1.2 3.3 7.2 3.9 5.1 5.5 2.3 3.6 16.3 3.2 17.9 19.0 6.3 11.6 12.2 13.5 5.1 3.5 3.8 4.2 10.0 0.5 5.7 7.9 3.5 3.4 5.0 5.4 6.0 3.4 3.2 3.3 22.3 20.4 12.7 37.4 6.1 1.1 20.5 17.8 4.6 4.3 4.0 7.0 4.5 3.5 5.5 7.2 1.5 13.9 7.9 9.5 3.6 30.8 19.8 2.3 30.1 15.2 22.6 29.0 6.8 3.9 17.3 22.7 84.2 31.4 51.2 67.7 20.1 94.1 63.1 37.3 60.5 34.2 40.3 34.8 28.5 18.1 34.1 24.8 65.0 14.2 15.7 36.9 58.3 123.1 53.2 91.7 38.3 74.0 20.7 13.0 17.0 28.3 69.7 20.5 67.5 188.4 57.7 23.9 68.9 100.1 26.7 46.6 20.1 21.9 54.8 14.8 24.7 38.1 15.2 68.0 33.4 53.9 0.8 73.5 54.6 62.5 53.9 21.4 22.0 22.4 0.3 0.2 0.0 3.1 0.1 8.2 10.6 5.3 5.4 6.9 6.5 1.9 2.7 0.6 3.7 0.0 0.3 13.5 1.8 3.3 3.9 2.3 3.6 3.8 4.2 3.5 3.4 3.3 4.3 3.5 3.6 2.7 9.6 1.5 2.0 10.3 46.0 34.5 6.4 14.8 1.1 3.7 2.3 0.6 7.2 9.6 3.7 12.5 0.9 2.5 21.5 3.9 9.5 0.3 13.6 2.8 13.7 6.0 1.7 3.9 8.2 19.1 8.3 6.1 22.9 2.5 5.0 0.7 0.0 4.8 0.0 4.4 10.1 4.1 0.3 15.0 1.0 0.9 3.6 23.2 6.5 3.7 1.2 1.0 4.0 0.4 25.9 10.0 2.6 23.6 20.6 15.1 6.4 0.1 8.0 6.6 2.8 3.1 0.3 7.5 8.6 50.3 4.5 5.7 4.9 24.7 16.6 SLC8B1 "FLJ22233, NCKX6, NCLX, SLC24A6" ENSG00000089060 "Solute carrier family 8 member B1" Q6J4K2 12 113298759-113359493 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sensory transduction, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 75.4" "Cell type enhanced" "Detected in many" "Theca cells: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 54.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040668 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "HPA040668: AB_10793861" "prognostic favorable (9.52e-4)" "unprognostic (1.58e-1)" "unprognostic (1.27e-1)" "unprognostic (4.30e-1)" "unprognostic (1.93e-2)" "unprognostic (2.80e-3)" "unprognostic (1.90e-1)" "unprognostic (6.52e-2)" "unprognostic (1.84e-1)" "unprognostic (2.68e-2)" "unprognostic (2.60e-1)" "unprognostic (5.14e-1)" "unprognostic (1.75e-1)" "unprognostic (1.54e-3)" "unprognostic (9.39e-2)" "unprognostic (1.14e-1)" "prognostic favorable (5.02e-4)" 18.5 75.4 7.6 14.8 10.3 17.7 15.1 8.6 8.6 19.3 4.4 15.6 10.6 11.9 7.9 15.8 13.1 11.3 11.0 7.5 8.0 17.2 17.6 20.6 13.8 14.2 9.5 55.5 18.1 7.5 15.3 8.1 10.6 16.9 9.3 1.4 16.9 9.1 10.0 19.4 16.9 6.9 9.3 29.4 12.1 13.6 11.6 18.0 13.1 5.6 9.9 12.7 15.2 11.2 25.3 5.5 3.2 7.0 15.5 10.9 10.6 8.3 23.8 10.6 10.3 5.4 21.1 6.6 18.5 10.8 9.2 20.1 9.8 5.7 5.1 16.3 3.1 13.3 13.1 6.2 25.8 33.9 28.7 11.1 16.9 12.2 5.2 9.1 24.5 24.0 27.7 3.3 6.0 5.9 10.6 27.5 5.7 8.2 14.2 3.9 4.2 8.3 11.4 34.7 0.2 5.4 22.5 45.1 5.4 4.2 8.0 13.1 54.3 7.5 8.8 22.4 5.0 4.5 10.3 5.0 9.6 19.2 6.0 4.1 16.5 32.8 8.0 24.1 10.2 3.3 14.5 7.9 19.1 4.4 28.8 13.5 10.3 6.1 24.8 14.3 19.4 15.8 7.6 10.3 8.6 8.6 7.5 8.0 14.2 9.5 10.6 9.3 11.6 11.2 9.3 12.8 12.6 13.7 5.8 4.5 13.2 8.0 4.6 2.4 8.4 6.5 4.3 8.6 10.9 12.9 10.4 7.8 9.2 30.6 5.9 13.0 1.5 6.0 9.4 9.6 4.9 1.7 7.7 17.4 8.6 13.6 14.3 15.5 21.5 32.4 6.4 12.0 21.6 0.0 3.9 13.3 4.1 21.8 22.6 1.5 24.5 32.4 1.8 22.5 17.8 2.8 5.2 4.0 6.2 22.5 20.7 28.2 3.3 19.1 23.6 3.3 4.5 0.8 32.9 9.9 13.3 1.0 3.9 12.2 7.1 10.7 9.8 96.7 13.3 21.3 SMAD1 "JV4-1, MADH1, MADR1" ENSG00000170365 "SMAD family member 1" Q15797 4 145481194-145559176 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 195.9;Endothelial cells: 76.3;Late spermatids: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 46.2;non-classical monocyte: 22.2" "Group enriched" "Detected in many" 5 "granulocytes: 46.2;monocytes: 22.2" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005389 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "CAB005389: AB_656608" "unprognostic (8.20e-2)" "unprognostic (1.63e-1)" "unprognostic (2.76e-2)" "unprognostic (1.11e-1)" "unprognostic (3.74e-1)" "unprognostic (6.85e-2)" "unprognostic (1.70e-1)" "unprognostic (6.02e-2)" "unprognostic (2.30e-1)" "unprognostic (8.24e-2)" "unprognostic (5.31e-2)" "unprognostic (4.68e-2)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" "unprognostic (5.88e-2)" "unprognostic (1.14e-3)" "unprognostic (3.15e-2)" 19.6 5.3 16.7 10.9 21.9 5.8 15.9 15.3 18.2 20.4 6.9 20.4 15.4 29.0 32.7 16.3 24.4 17.1 13.1 13.2 16.6 12.6 20.2 12.3 17.6 14.6 18.3 11.7 13.3 29.1 6.0 11.4 14.5 12.5 20.8 6.5 12.9 17.2 20.7 24.4 15.7 30.4 13.6 14.0 10.6 13.9 16.4 18.3 17.4 17.8 13.7 17.9 8.9 13.6 9.6 12.6 23.5 27.3 8.7 12.8 11.5 13.9 32.6 22.0 16.4 6.2 34.0 9.8 8.0 31.8 9.7 14.1 26.6 30.2 12.8 0.0 13.5 0.0 10.0 13.1 23.2 15.8 2.4 17.6 35.2 11.8 22.9 17.9 110.7 20.7 11.1 0.4 27.0 9.6 24.4 0.3 21.8 15.3 14.6 47.0 21.1 28.5 25.9 17.1 35.3 17.6 18.8 40.3 9.6 14.1 14.0 0.2 32.4 10.5 14.5 11.3 8.6 31.1 0.0 56.1 16.7 0.3 11.1 46.2 3.6 1.5 0.0 9.4 0.0 0.0 0.6 0.0 6.8 0.1 0.3 0.0 0.0 2.4 22.2 0.0 1.3 1.3 16.7 21.9 15.3 18.2 13.2 16.6 14.6 18.3 14.5 13.6 16.4 13.6 62.9 9.6 10.9 54.9 0.1 11.5 17.5 22.0 45.5 6.6 8.6 9.3 3.6 12.8 16.3 14.7 14.6 5.2 0.8 13.2 7.9 12.6 195.9 19.5 12.1 76.3 9.1 8.4 47.7 18.5 2.7 11.5 12.2 24.8 0.0 10.0 10.4 12.0 2.5 10.1 43.2 10.4 28.5 6.5 2.7 80.7 4.4 4.5 1.8 26.2 3.2 5.3 0.0 66.9 22.0 12.0 10.2 5.7 0.3 17.5 6.6 11.5 12.7 5.9 0.0 19.0 10.6 8.3 16.8 19.9 12.6 2.2 1.2 6.9 8.8 17.2 SNAP23 "HsT17016, SNAP23A, SNAP23B" ENSG00000092531 "Synaptosome associated protein 23" O00161 15 42491233-42545356 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 326.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 675.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001214, CAB037083, CAB037317" Approved Supported "Plasma membrane" NA NA 3900000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "CAB037083: AB_477494, CAB037317: AB_261925, HPA001214: AB_1080037" "unprognostic (1.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (3.76e-3)" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (9.67e-3)" "unprognostic (1.60e-1)" "unprognostic (2.60e-1)" "unprognostic (2.93e-1)" "unprognostic (7.31e-2)" "unprognostic (1.36e-1)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (8.95e-2)" "unprognostic (1.10e-1)" "unprognostic (3.93e-2)" 44.4 30.3 23.0 62.9 27.7 35.1 38.2 25.7 46.3 37.5 28.6 52.8 50.3 43.2 35.3 31.9 29.8 40.2 44.6 23.5 24.8 42.4 44.4 45.2 84.6 28.0 25.9 34.6 24.2 36.2 12.9 68.9 31.3 49.2 51.2 12.8 45.2 30.9 43.9 26.5 56.4 48.3 25.6 70.3 39.9 36.1 27.5 38.0 33.1 28.7 78.7 42.5 23.9 37.2 58.3 29.7 55.7 54.7 91.8 70.4 85.1 77.6 61.8 50.8 59.1 93.0 27.8 35.1 91.3 52.3 48.1 52.7 63.2 50.1 70.9 58.4 35.3 149.2 30.5 89.1 66.8 57.4 136.6 59.1 37.9 43.5 70.4 64.7 192.9 69.4 121.6 31.4 67.1 24.1 68.3 69.4 46.0 94.3 22.8 122.4 33.8 55.1 71.8 57.8 9.0 36.3 57.2 51.3 56.4 83.5 76.2 91.6 155.0 46.6 61.2 52.1 80.4 59.1 122.3 153.2 56.3 120.0 62.8 244.8 159.8 675.6 51.4 237.6 60.2 110.2 53.5 50.2 148.2 103.9 68.0 52.4 361.9 70.7 236.0 62.6 66.4 179.4 23.0 27.7 25.7 46.3 23.5 24.8 28.0 25.9 31.3 25.6 27.5 37.2 58.9 112.2 30.5 30.7 79.0 50.7 107.6 30.8 34.7 7.7 41.9 19.8 19.2 38.6 32.8 20.2 20.9 75.9 45.3 61.3 56.7 71.1 207.6 34.4 38.6 77.1 14.9 25.0 21.2 52.2 109.5 44.3 32.6 41.2 83.5 22.4 77.4 28.0 88.9 5.0 23.6 80.2 52.9 125.4 112.8 326.0 39.1 131.8 44.4 36.5 120.0 14.6 53.5 39.7 54.6 110.8 52.8 60.5 27.9 79.9 55.0 76.2 42.6 18.4 52.6 42.1 40.6 16.7 7.9 29.3 38.5 142.6 48.2 47.8 39.7 64.7 SNCA "NACP, PARK1, PARK4, PD1" ENSG00000145335 "Synuclein alpha" P37840 4 89700345-89838315 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Alzheimer disease, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 273.6;brain: 128.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 1225.0;Excitatory neurons: 251.5;Melanocytes: 352.2;Oligodendrocytes: 195.4" "Cancer enriched" "Detected in many" 8 "melanoma: 37.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 102.9" "Group enriched" "Detected in all" 4 "dendritic cells: 102.9;granulocytes: 51.5;monocytes: 66.9" "Cell line enhanced" "Detected in many" "HEL: 221.5;HUVEC TERT2: 269.8;RT4: 137.3;SK-MEL-30: 271.6;TIME: 311.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005459, CAB010877" Enhanced "Intracellular and membrane" NA NA 28000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010877: AB_261518, HPA005459: AB_2667324" "unprognostic (4.80e-2)" "unprognostic (1.52e-1)" "unprognostic (8.13e-2)" "unprognostic (1.05e-3)" "unprognostic (2.65e-2)" "unprognostic (1.54e-2)" "unprognostic (1.78e-2)" "unprognostic (3.44e-2)" "unprognostic (1.73e-2)" "unprognostic (3.85e-3)" "unprognostic (1.01e-3)" "unprognostic (2.09e-2)" "unprognostic (1.57e-1)" "unprognostic (2.51e-3)" "unprognostic (1.68e-1)" "unprognostic (3.93e-4)" "unprognostic (7.48e-3)" 16.0 9.9 91.5 10.0 112.2 273.6 7.8 47.2 128.2 26.1 16.1 28.5 3.3 34.3 3.4 8.5 11.2 5.4 20.9 115.2 69.1 12.4 2.9 16.6 2.2 97.5 88.3 29.3 2.2 1.1 28.7 28.3 89.9 17.3 6.9 20.3 15.9 9.7 1.2 16.4 8.6 33.3 36.0 15.2 6.4 3.2 76.2 5.3 10.2 8.5 4.8 9.3 23.2 107.0 0.5 1.0 40.1 0.0 0.7 0.0 0.6 0.4 44.5 1.6 3.0 0.0 0.0 0.2 12.0 0.0 0.0 9.3 53.6 97.7 1.5 0.0 22.6 221.5 115.4 0.5 84.2 0.0 1.4 2.1 38.2 0.0 109.5 117.3 269.8 2.2 2.0 0.6 0.2 0.0 2.1 0.3 10.6 0.2 4.8 0.0 15.8 0.0 0.3 137.3 23.2 15.6 0.2 0.3 271.6 29.0 0.0 0.4 311.4 1.3 8.0 0.1 0.8 0.2 0.2 0.1 8.8 0.2 87.4 51.5 66.9 0.1 0.3 27.7 0.1 4.2 1.9 0.3 84.6 1.7 1.0 0.5 11.1 17.3 8.2 102.9 0.0 63.7 91.5 112.2 47.2 128.2 115.2 69.1 97.5 88.3 89.9 36.0 76.2 107.0 1.8 0.0 0.6 40.1 2.6 76.6 16.3 173.4 101.3 10.4 0.9 14.4 13.4 0.0 21.5 11.0 0.0 10.1 10.1 0.1 1.9 0.0 0.6 0.3 1.1 19.4 1.8 1225.0 251.5 0.2 1.9 32.7 0.0 0.3 0.0 23.9 7.5 0.8 62.3 10.1 53.8 0.0 44.7 17.2 64.2 1.5 2.1 100.7 352.2 76.8 24.4 19.4 4.1 95.5 195.4 0.2 0.0 0.0 0.5 11.3 0.0 2.0 6.6 7.4 13.1 0.5 5.3 19.6 16.9 4.5 22.6 3.4 3.8 43.6 0.0 3.4 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 126.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 37.6 10.3 9.7 17.2 9.7 58.4 26.5 27.7 13.2 21.7 9.8 14.6 16.1 23.1 7.8 19.7 13.6 20.4 16.3 9.5 12.5 20.0 25.4 26.4 19.8 14.0 11.5 14.4 22.7 18.5 11.4 33.3 14.7 11.2 11.9 18.8 11.4 10.8 14.3 30.3 17.2 22.9 9.5 33.0 14.4 11.1 13.2 40.5 27.3 21.6 14.7 19.8 21.7 8.7 8.4 5.0 9.1 8.8 26.6 9.5 8.7 8.8 14.8 9.4 9.1 6.9 11.8 13.2 6.8 11.2 6.2 5.3 10.7 18.9 9.6 15.1 8.8 15.0 9.1 8.1 13.8 17.1 16.1 10.5 12.7 10.6 17.9 9.5 126.0 14.9 6.7 14.9 8.7 4.4 17.3 15.0 10.1 4.6 22.6 11.7 6.7 14.0 24.2 14.1 6.4 13.4 7.7 8.1 11.1 7.9 5.5 21.4 74.1 8.2 8.3 9.5 10.4 23.7 18.3 11.0 5.8 20.1 12.0 9.4 4.2 7.6 9.5 7.5 13.0 3.6 8.3 9.6 4.0 3.6 12.1 13.1 27.7 11.0 7.1 1.2 9.7 9.7 9.7 9.7 27.7 13.2 9.5 12.5 14.0 11.5 14.7 9.5 13.2 8.7 88.4 32.1 24.1 30.0 29.0 52.8 10.3 6.4 12.5 52.1 9.7 8.6 17.7 15.7 15.0 16.5 16.7 7.7 57.6 37.0 11.7 10.9 50.4 23.3 16.2 84.2 10.8 10.3 21.6 8.9 3.2 16.4 12.8 19.8 14.5 8.9 98.6 25.2 13.7 30.3 43.2 10.7 12.2 24.8 19.0 7.5 12.5 26.5 23.2 34.7 21.9 16.3 65.9 24.6 10.7 11.2 20.6 11.7 27.3 12.7 25.2 12.2 19.2 18.3 124.9 31.3 49.1 11.1 16.2 13.7 51.3 8.2 61.2 9.5 11.1 18.0 SNTB2 "D16S2531E, EST25263, SNT2B2, SNT3, SNTL" ENSG00000168807 "Syntrophin beta 2" Q13425 16 69187129-69309052 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.4;Muller glia cells: 214.1;Rod photoreceptor cells: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SiHa: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001394 Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA001394: AB_1080170" "unprognostic (4.86e-1)" "unprognostic (3.26e-2)" "unprognostic (2.77e-2)" "unprognostic (8.07e-3)" "unprognostic (6.46e-2)" "unprognostic (9.68e-2)" "unprognostic (1.89e-2)" "unprognostic (5.50e-2)" "unprognostic (1.22e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-2)" "unprognostic (3.64e-2)" "unprognostic (5.77e-3)" "unprognostic (1.71e-2)" "unprognostic (7.43e-2)" "unprognostic (1.73e-2)" "unprognostic (1.88e-1)" 11.0 5.0 3.3 5.2 3.9 2.7 8.8 1.0 6.7 11.0 10.1 6.7 3.7 10.4 5.1 7.0 8.7 7.1 5.3 4.6 0.8 6.7 3.8 8.6 5.6 2.5 0.9 6.2 4.1 12.4 4.0 5.2 0.9 8.2 5.3 21.6 5.2 5.5 5.7 8.5 6.0 8.7 0.6 5.7 6.1 7.1 1.5 5.8 10.5 3.8 4.9 8.7 8.7 3.7 7.2 10.9 7.4 5.8 26.6 35.6 9.1 13.9 19.3 10.7 11.8 10.7 6.5 9.0 8.3 16.2 5.6 12.9 10.0 6.8 13.9 4.0 5.5 4.0 11.1 9.2 8.8 0.3 5.9 25.6 4.9 17.6 7.1 11.1 32.4 2.5 2.3 13.8 13.1 8.2 3.0 1.4 5.0 4.2 8.6 18.1 6.5 16.8 5.7 10.9 2.8 6.1 42.6 6.0 4.4 5.5 7.1 0.5 25.4 20.0 9.6 14.2 13.0 3.1 5.2 10.0 12.8 1.4 9.3 0.4 0.2 0.3 0.9 0.3 0.9 0.2 0.4 0.5 0.2 0.2 0.2 1.1 0.9 0.7 0.3 0.1 0.5 0.3 3.3 3.9 1.0 6.7 4.6 0.8 2.5 0.9 0.9 0.6 1.5 3.7 55.9 19.2 11.7 36.6 9.0 38.0 28.0 17.1 70.0 33.2 19.0 25.0 9.2 10.0 10.4 27.6 41.7 9.5 33.7 29.0 3.9 9.7 25.9 20.6 61.3 81.4 10.3 4.8 151.4 24.1 7.9 53.1 20.9 28.7 1.3 15.8 126.7 11.1 6.9 5.0 62.6 16.6 8.2 33.1 29.3 27.5 59.0 12.9 30.2 33.7 8.6 214.1 47.4 30.7 27.9 16.3 32.8 65.1 20.7 40.9 12.7 34.5 10.0 136.7 6.6 26.0 35.6 27.9 15.4 30.7 38.8 3.7 32.8 20.2 19.6 28.7 SNX6 ENSG00000129515 "Sorting nexin 6" Q9UNH7 14 34561093-34630160 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049374 Approved Supported Endosomes,Lysosomes NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Endosomes, Lysosomes" "HPA049374: AB_2680734" "unprognostic (1.89e-1)" "unprognostic (6.49e-2)" "unprognostic (1.46e-1)" "unprognostic (3.06e-2)" "unprognostic (1.12e-1)" "unprognostic (2.36e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (1.23e-1)" "unprognostic (6.63e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.68e-4)" "unprognostic (1.91e-1)" "unprognostic (3.48e-2)" "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (8.82e-2)" "unprognostic (2.10e-2)" 50.0 36.5 38.0 46.8 44.4 42.0 36.7 41.2 62.9 40.4 40.2 50.4 74.2 33.6 30.1 40.0 31.2 39.7 33.7 35.4 41.0 44.4 38.9 33.4 56.5 45.4 42.9 31.3 25.1 78.3 14.9 74.5 44.9 25.8 49.1 14.8 27.2 29.5 30.5 30.3 49.1 43.9 44.8 49.2 39.6 36.0 42.1 45.1 34.1 29.2 47.8 50.2 29.6 51.4 112.3 65.3 73.5 48.9 114.5 224.7 99.4 113.1 124.0 110.4 95.4 61.6 115.4 73.2 79.0 153.2 44.1 67.8 81.1 85.8 187.9 93.5 31.7 44.6 34.9 115.9 108.5 77.2 46.8 154.1 98.9 80.7 109.7 100.4 151.7 53.3 48.8 56.3 146.9 68.4 69.9 41.4 40.2 97.7 73.0 74.3 84.4 64.1 135.2 84.6 56.7 61.1 89.9 72.9 94.6 65.0 77.6 47.5 150.8 74.6 52.6 67.8 72.0 55.9 95.9 82.9 37.6 41.6 86.1 73.5 74.2 93.4 73.1 97.4 95.8 71.5 97.0 84.8 66.5 68.0 73.3 79.2 126.5 74.0 101.3 47.6 102.0 109.0 38.0 44.4 41.2 62.9 35.4 41.0 45.4 42.9 44.9 44.8 42.1 51.4 130.2 86.6 49.7 17.6 77.5 51.4 63.0 109.7 69.4 43.4 51.1 67.8 73.4 27.1 87.2 80.9 22.9 166.7 108.9 73.0 125.2 88.1 6.6 74.9 110.1 87.5 52.0 55.5 25.5 64.7 126.3 88.0 68.8 114.3 85.4 93.5 124.6 36.8 251.1 21.9 31.2 62.7 67.1 196.1 73.0 15.3 64.3 155.7 62.2 26.2 155.4 69.6 88.6 21.1 52.5 74.1 77.9 94.8 51.2 84.0 54.8 127.0 73.3 39.4 59.2 74.2 133.8 164.6 167.9 90.0 65.8 254.6 109.4 346.2 82.0 76.8 SOX7 ENSG00000171056 "SRY-box transcription factor 7" Q9BT81 8 10723768-10730511 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "vagina: 42.4" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal keratinocytes: 61.2;Basal prostatic cells: 67.6;Basal squamous epithelial cells: 148.5;Endothelial cells: 115.1;Squamous epithelial cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 11.8;hTCEpi: 21.3;HUVEC TERT2: 25.2;TIME: 6.8" "Low region specificity" "Detected in many" HPA009065 Approved Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "Golgi apparatus" "HPA009065: AB_1857390" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (1.15e-3)" "unprognostic (1.29e-2)" "unprognostic (1.60e-1)" "unprognostic (1.65e-1)" "unprognostic (3.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.74e-2)" "unprognostic (7.26e-2)" "unprognostic (7.44e-2)" "unprognostic (1.09e-1)" "unprognostic (7.71e-3)" "unprognostic (2.45e-3)" "unprognostic (2.38e-1)" "unprognostic (5.41e-3)" "unprognostic (4.84e-3)" 22.6 3.8 2.5 1.0 2.3 0.1 11.9 1.9 2.6 27.0 1.4 4.2 0.1 4.3 1.1 26.8 4.5 3.6 18.5 2.1 1.8 5.1 4.3 23.2 1.7 2.6 2.2 1.5 2.6 1.0 5.6 17.3 2.5 5.4 1.1 0.4 10.5 2.7 9.8 20.2 3.6 2.3 2.5 2.4 3.7 0.7 2.7 1.5 7.6 6.4 1.9 4.6 42.4 2.0 5.8 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.3 0.6 11.8 3.4 4.2 0.1 0.1 0.4 0.1 0.3 0.1 0.0 0.2 0.2 0.1 21.3 0.0 4.3 0.0 25.2 0.0 0.6 0.3 0.0 0.2 0.2 0.2 1.6 0.9 3.2 1.2 0.0 0.0 0.0 2.1 0.6 3.4 2.2 0.0 0.0 1.4 0.0 0.1 6.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.3 1.9 2.6 2.1 1.8 2.6 2.2 2.5 2.5 2.7 2.0 115.4 0.0 11.5 0.3 1.1 61.2 67.6 24.5 148.5 1.2 5.2 4.7 4.8 1.5 6.3 0.0 4.2 4.3 0.1 0.2 0.0 0.2 0.2 14.9 1.9 115.1 0.0 0.0 4.6 0.2 0.8 4.7 0.0 22.9 3.8 0.5 48.5 4.9 0.7 0.0 2.9 0.2 10.2 1.9 8.7 0.1 0.9 0.9 3.6 10.3 0.3 0.5 0.0 1.5 0.8 0.5 0.0 0.4 1.2 17.8 0.1 0.6 3.2 2.2 0.0 8.5 4.4 2.4 1.6 98.9 40.6 12.4 1.8 1.2 0.4 26.6 SPAAR "LINC00961, SPAR" ENSG00000235387 "Small regulatory polypeptide of amino acid response" A0A1B0GVQ0 9 35909490-35937153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.4;breast: 10.8" "Cell type enriched" "Detected in some" 7 "Adipocytes: 42.3" "Cancer enhanced" "Detected in many" "renal cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HUVEC TERT2: 34.0;TIME: 40.1" "Not detected" "Not detected" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.17e-1)" "unprognostic (2.19e-2)" "unprognostic (1.91e-2)" "unprognostic (7.00e-3)" "unprognostic (4.23e-2)" "unprognostic (2.61e-3)" "unprognostic (6.95e-2)" "unprognostic (1.00e-1)" "unprognostic (3.40e-3)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (7.72e-2)" "unprognostic (7.12e-3)" "unprognostic (1.67e-2)" "unprognostic (3.04e-1)" "unprognostic (1.27e-1)" "unprognostic (3.22e-1)" 12.4 1.2 2.9 0.6 2.5 0.0 10.8 2.2 3.3 0.7 1.1 1.2 0.3 1.2 0.1 0.5 1.2 0.6 8.9 2.3 2.2 4.2 0.8 3.2 0.4 3.0 2.6 0.7 0.5 0.5 0.6 4.7 3.1 1.0 0.4 1.4 0.7 0.5 3.1 0.9 0.9 0.6 2.3 0.7 0.9 7.5 3.3 0.2 1.9 1.8 0.0 1.5 0.8 2.4 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.6 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.4 0.1 0.2 0.0 0.0 34.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 40.1 0.0 0.8 2.7 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.5 2.2 3.3 2.3 2.2 3.0 2.6 3.1 2.3 3.3 2.4 42.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 5.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 SPATA22 NYD-SP20 ENSG00000141255 "Spermatogenesis associated 22" Q8NHS9 17 3440019-3513852 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 52 "testis: 230.2" "Cell type enhanced" "Detected in some" "Early spermatids: 293.3;Late spermatids: 207.8;Spermatocytes: 1047.6" "Cancer enriched" "Detected in single" 10 "testis cancer: 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "K-562: 7.7;TIME: 10.9" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 74: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (4.09e-2)" "unprognostic (9.31e-2)" "unprognostic (2.54e-2)" "unprognostic (7.07e-2)" "unprognostic (9.05e-2)" "unprognostic (1.98e-2)" "unprognostic (6.79e-4)" "unprognostic (4.33e-1)" "unprognostic (1.87e-1)" "unprognostic (1.27e-1)" 1.1 0.6 0.8 0.2 1.2 0.1 1.1 0.5 1.2 0.7 0.0 0.3 0.2 0.4 0.2 0.3 0.5 0.1 0.4 0.6 0.7 0.4 0.2 0.3 0.3 1.2 1.0 0.2 0.2 2.8 0.2 3.5 1.1 0.3 0.0 0.2 0.2 0.1 0.6 0.2 0.3 0.2 0.5 0.6 0.1 230.2 2.2 0.2 0.2 0.3 0.0 0.3 0.2 4.4 0.0 0.0 0.1 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.2 0.1 0.2 0.0 0.1 0.8 1.2 0.5 1.2 0.6 0.7 1.2 1.0 1.1 0.5 2.2 4.4 0.3 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.6 0.0 0.0 0.0 0.0 3.7 0.2 0.0 0.0 0.0 293.3 0.1 0.2 0.7 0.0 0.0 4.5 0.0 17.3 0.7 0.0 0.1 0.0 0.1 0.0 0.1 1.1 0.0 1.2 0.1 0.0 0.6 0.3 207.8 14.3 0.9 0.0 0.0 0.0 0.0 0.0 1.5 45.8 0.0 0.0 8.6 0.0 0.0 0.0 0.2 0.0 0.0 13.1 0.9 0.4 1047.6 58.8 0.0 0.1 1.2 0.1 0.2 0.0 0.0 SPATS2 "FLJ13117, SCR59, SPATA10" ENSG00000123352 "Spermatogenesis associated serine rich 2" Q86XZ4 12 49366584-49527425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 144.8;Spermatogonia: 138.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 6.0;dendritic cells: 8.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038642, HPA038643, HPA076823" Uncertain Enhanced Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA038642: AB_2676128, HPA038643: AB_10672523, HPA076823: " "unprognostic (2.87e-2)" "unprognostic (2.63e-1)" "unprognostic (2.20e-2)" "unprognostic (1.89e-1)" "unprognostic (5.56e-2)" "unprognostic (6.33e-2)" "prognostic unfavorable (9.57e-8)" "unprognostic (4.55e-2)" "unprognostic (6.32e-2)" "prognostic favorable (1.44e-4)" "unprognostic (2.64e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.20e-4)" "unprognostic (9.51e-2)" "unprognostic (1.16e-1)" "unprognostic (2.57e-1)" "unprognostic (4.81e-1)" 7.7 7.8 9.1 10.3 11.0 6.5 9.4 15.3 12.8 12.8 10.9 11.0 11.6 11.1 7.9 6.8 6.9 11.1 7.1 11.5 6.2 9.6 4.8 8.0 15.7 10.7 7.8 8.0 12.2 21.5 13.8 8.9 11.1 9.9 11.5 10.1 18.4 6.1 11.1 16.3 10.3 11.3 4.4 10.8 13.1 26.1 8.1 13.2 12.9 6.4 18.1 10.3 13.1 10.4 17.9 39.7 33.2 38.7 19.1 29.3 10.7 20.8 29.8 34.2 29.6 36.0 39.0 44.4 47.5 18.4 22.5 20.8 28.9 39.1 43.8 33.9 17.2 40.4 28.2 29.1 34.7 11.1 23.1 25.6 19.0 53.8 50.9 111.8 82.0 19.8 21.7 38.9 35.2 32.3 22.7 16.5 34.2 29.0 40.1 32.7 56.5 53.4 31.9 22.5 37.2 33.4 45.4 28.6 49.0 20.4 49.2 12.0 75.7 15.1 36.5 13.5 13.2 52.4 65.7 37.5 19.7 18.6 22.0 1.6 1.3 0.3 1.7 0.4 1.7 6.0 1.4 1.0 4.1 3.2 1.2 1.0 0.9 1.3 0.3 8.0 1.1 1.1 9.1 11.0 15.3 12.8 11.5 6.2 10.7 7.8 11.1 4.4 8.1 10.4 35.0 19.2 19.8 34.6 33.8 58.0 48.8 52.0 25.0 44.5 29.9 29.8 9.9 35.8 19.6 36.8 22.9 9.7 19.2 9.6 5.9 26.0 77.4 28.3 63.1 44.6 36.6 22.7 114.0 27.9 12.0 34.8 23.0 45.1 10.8 37.1 29.3 5.6 8.0 42.1 67.6 21.6 20.3 9.2 39.8 46.3 31.7 15.3 19.6 27.2 15.0 22.3 16.5 59.3 30.6 46.4 11.7 33.4 144.8 36.4 13.3 12.4 10.1 5.9 52.6 20.5 27.7 137.3 138.1 17.0 60.4 5.3 16.2 31.5 30.2 29.4 SPG7 "CAR, CMAR, SPG5C" ENSG00000197912 "SPG7 matrix AAA peptidase subunit, paraplegin" Q9UQ90 16 89490719-89557766 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "unprognostic (1.42e-1)" "unprognostic (1.72e-1)" "unprognostic (4.12e-2)" "prognostic favorable (2.22e-4)" "unprognostic (4.10e-1)" "unprognostic (1.11e-2)" "unprognostic (1.14e-1)" "unprognostic (1.50e-1)" "unprognostic (1.54e-1)" "unprognostic (2.33e-1)" "prognostic favorable (4.91e-4)" "unprognostic (3.56e-2)" "unprognostic (7.01e-2)" "unprognostic (1.44e-2)" "unprognostic (2.58e-1)" "unprognostic (1.71e-1)" "prognostic favorable (4.25e-4)" 29.8 44.8 19.3 7.0 18.8 8.2 27.9 21.3 28.6 31.5 18.5 33.3 9.9 31.8 4.0 28.2 26.4 6.8 52.3 19.4 18.3 32.4 47.0 24.9 8.9 19.7 18.6 39.0 31.9 13.8 38.7 5.9 20.3 31.2 8.1 9.9 29.0 9.7 56.7 31.3 35.5 9.0 16.9 34.1 31.1 31.9 18.7 10.5 53.1 31.0 8.0 30.1 26.9 20.0 11.5 28.3 17.3 26.6 33.2 24.2 10.9 27.3 24.6 21.0 10.4 23.0 22.3 16.5 32.5 20.1 16.2 30.5 21.5 24.4 14.7 11.7 25.3 11.4 12.0 43.4 16.2 5.5 10.3 15.2 20.1 12.8 14.1 27.9 25.6 22.0 23.1 5.5 21.7 21.0 14.4 22.5 21.9 23.8 21.4 31.8 26.2 10.8 15.9 17.3 16.4 10.5 44.9 8.3 9.5 15.2 22.6 17.0 33.7 13.9 17.2 12.0 12.2 13.7 19.8 12.8 17.7 19.8 17.7 4.5 2.5 3.9 2.7 2.4 2.6 1.6 1.7 1.3 2.8 3.4 3.1 2.0 2.9 3.7 1.7 2.3 1.8 1.0 19.3 18.8 21.3 28.6 19.4 18.3 19.7 18.6 20.3 16.9 18.7 20.0 53.9 48.1 49.4 39.2 45.6 15.9 27.9 30.1 44.9 57.8 31.2 37.2 45.8 22.8 41.5 35.0 95.9 39.9 47.6 42.3 19.6 40.0 66.0 50.5 41.7 49.9 37.2 27.3 58.5 25.8 28.8 35.9 67.2 54.1 21.5 95.3 51.0 38.1 32.2 40.4 53.1 43.8 30.5 34.8 21.8 22.1 42.9 35.2 21.4 35.6 42.6 30.5 51.5 87.0 46.2 39.5 39.5 33.4 43.5 29.5 68.2 23.8 37.7 73.7 6.6 36.9 36.2 57.5 36.5 36.7 18.0 25.9 45.5 68.3 51.0 28.7 SPRED3 ENSG00000188766 "Sprouty related EVH1 domain containing 3" Q2MJR0 19 38388421-38399587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.0;pituitary gland: 5.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 6.6;Enteroendocrine cells: 10.8;Excitatory neurons: 9.8;Inhibitory neurons: 10.4" "Cancer enhanced" "Detected in many" "glioma: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 12.9;TIME: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071521 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA071521: " "unprognostic (1.09e-1)" "unprognostic (1.88e-3)" "unprognostic (8.71e-3)" "unprognostic (3.35e-3)" "unprognostic (3.70e-2)" "unprognostic (2.00e-3)" "unprognostic (2.09e-3)" "unprognostic (7.77e-3)" "unprognostic (1.49e-1)" "unprognostic (9.22e-3)" "unprognostic (1.69e-2)" "unprognostic (3.09e-2)" "unprognostic (1.40e-11)" "unprognostic (6.21e-4)" "unprognostic (3.67e-1)" "unprognostic (1.04e-3)" "unprognostic (8.45e-3)" 0.7 0.4 3.2 1.0 3.7 0.3 0.5 0.5 5.0 0.6 0.4 0.5 1.8 0.4 0.3 0.4 0.6 0.7 0.7 4.5 8.0 2.3 0.2 0.7 0.2 4.4 5.0 0.3 1.1 1.7 5.6 0.3 4.6 1.0 0.2 1.5 0.5 0.3 0.9 0.8 1.3 0.8 1.1 0.1 0.4 1.1 5.0 0.1 0.6 0.0 0.2 0.6 0.5 2.7 0.3 1.2 4.0 3.3 0.6 1.9 2.3 8.1 5.3 2.6 2.4 0.4 0.8 0.2 2.9 2.7 2.1 0.1 0.7 1.0 2.4 0.8 1.5 0.1 0.3 0.5 1.4 2.2 0.1 1.3 0.9 6.2 1.8 12.9 8.3 0.6 0.7 1.5 8.1 0.4 0.0 0.1 1.8 0.5 4.0 1.0 1.4 0.1 5.7 0.7 0.2 3.1 0.2 0.2 0.4 1.7 0.7 0.1 15.9 2.9 9.0 2.4 4.5 0.6 0.3 0.6 9.8 0.3 5.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 3.2 3.7 0.5 5.0 4.5 8.0 4.4 5.0 4.6 1.1 5.0 2.7 1.1 0.0 0.0 2.0 0.4 0.0 1.3 0.4 1.2 6.6 1.5 2.4 1.2 0.0 0.3 1.8 2.1 0.5 0.3 0.5 0.0 1.0 2.0 0.7 1.1 1.5 10.8 0.0 9.8 0.6 0.3 0.5 0.0 1.6 0.0 0.3 0.7 0.0 0.1 1.7 10.4 1.2 0.0 0.0 0.0 0.2 0.3 0.5 0.0 1.0 0.0 1.9 1.0 5.0 2.2 3.0 0.1 0.0 0.0 1.2 2.7 0.1 0.1 0.3 0.0 2.3 1.2 1.5 1.0 0.5 0.1 0.8 0.4 0.2 0.8 0.7 SPTBN1 ENSG00000115306 "Spectrin beta, non-erythrocytic 1" Q01082 2 54456317-54671446 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 615.4;Peritubular cells: 663.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012685, HPA013149" Supported Approved "Golgi apparatus" NA Yes 1500000 "Cluster 39: Non-specific - mRNA processing" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA012685: AB_1857433, HPA013149: AB_1857434" "unprognostic (2.72e-1)" "unprognostic (4.44e-3)" "unprognostic (3.00e-2)" "unprognostic (3.25e-1)" "unprognostic (4.09e-2)" "unprognostic (7.95e-2)" "unprognostic (9.24e-2)" "unprognostic (3.72e-2)" "unprognostic (7.31e-2)" "unprognostic (1.67e-1)" "unprognostic (2.26e-2)" "unprognostic (7.25e-2)" "prognostic favorable (2.59e-5)" "unprognostic (2.31e-1)" "unprognostic (2.73e-1)" "unprognostic (1.68e-3)" "unprognostic (5.18e-3)" 187.3 70.9 210.6 34.7 205.1 37.6 78.7 97.4 166.1 54.1 94.2 62.8 32.7 52.0 36.3 41.7 56.2 69.2 135.9 156.2 99.7 65.3 83.8 131.6 28.9 141.2 154.4 73.2 45.5 129.2 27.8 97.4 120.4 43.8 52.4 56.0 55.1 74.4 54.0 39.4 46.8 59.9 134.8 58.7 55.6 32.6 214.6 29.3 72.8 87.2 30.0 45.6 38.6 163.6 96.5 150.5 60.4 57.2 234.7 158.8 74.8 40.2 82.3 63.7 61.4 101.7 66.6 0.4 112.1 142.0 55.1 110.9 85.1 128.0 66.0 0.8 35.6 43.7 118.4 166.2 97.7 59.7 24.4 62.3 64.8 193.8 119.7 77.6 151.6 95.1 50.0 64.0 86.1 21.6 105.0 14.5 66.3 129.6 70.2 116.2 95.0 37.2 92.2 120.6 36.3 113.3 121.5 39.5 88.1 58.9 19.6 9.9 235.2 89.9 79.0 110.2 58.2 62.8 42.8 32.7 98.1 17.7 163.7 2.3 0.4 2.8 3.7 0.0 3.9 3.7 3.4 3.6 1.3 3.5 5.0 3.6 0.6 5.2 0.0 1.1 3.2 3.1 210.6 205.1 97.4 166.1 156.2 99.7 141.2 154.4 120.4 134.8 214.6 163.6 615.4 407.1 124.6 233.4 45.7 83.1 50.0 64.7 42.7 94.4 60.8 58.0 262.9 144.4 100.6 145.3 73.0 28.3 31.7 343.6 7.9 223.7 12.1 140.4 80.3 426.4 83.1 21.5 231.3 121.9 42.0 271.6 139.7 115.7 35.4 68.2 228.5 184.6 14.2 141.3 195.4 135.5 77.3 17.7 47.0 31.5 503.2 16.6 147.7 294.2 9.7 131.9 36.0 154.8 283.1 243.3 109.9 663.5 76.3 75.6 142.8 44.1 187.3 93.6 164.3 340.3 171.9 54.7 53.3 79.7 68.2 11.1 49.2 56.6 151.9 88.1 SPTBN5 "BSPECV, HUBSPECV, HUSPECV" ENSG00000137877 "Spectrin beta, non-erythrocytic 5" Q9NRC6 15 41848146-41894053 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 8.8;retina: 26.9" "Group enriched" "Detected in many" 22 "Cone photoreceptor cells: 210.6;Rod photoreceptor cells: 211.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.7;SCLC-21H: 5.1;TIME: 13.6;WM-115: 4.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "spinal cord: 3.6" HPA055283 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA055283: " "unprognostic (5.46e-2)" "unprognostic (2.49e-1)" "unprognostic (3.28e-2)" "unprognostic (2.01e-1)" "unprognostic (2.26e-2)" "unprognostic (5.84e-3)" "unprognostic (1.12e-1)" "unprognostic (6.84e-3)" "unprognostic (6.40e-3)" "unprognostic (2.25e-1)" "unprognostic (2.96e-2)" "unprognostic (6.92e-2)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.28e-1)" "unprognostic (1.37e-2)" "unprognostic (1.11e-2)" 1.0 0.3 0.4 0.7 1.3 0.4 1.1 8.8 1.4 0.6 0.1 0.5 0.3 0.4 0.8 1.7 0.5 0.9 2.0 0.6 0.1 1.7 1.6 1.2 0.6 0.8 0.3 0.6 1.1 0.5 1.9 0.2 1.0 1.6 0.2 26.9 2.7 0.3 0.4 1.7 0.5 0.2 0.1 0.5 1.0 0.8 0.1 0.0 2.1 0.4 0.1 2.6 0.7 0.8 0.2 0.0 0.4 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.6 0.0 0.8 0.0 1.5 0.4 0.0 0.2 0.0 0.8 0.1 0.0 1.6 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.1 0.4 0.0 0.3 0.0 0.3 1.4 5.1 0.1 0.2 0.4 0.1 0.4 0.8 0.0 13.6 0.0 1.3 0.3 1.7 1.5 2.3 0.0 0.0 0.1 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 8.8 1.4 0.6 0.1 0.8 0.3 1.0 0.1 0.1 0.8 1.9 0.0 2.4 2.9 0.2 0.8 0.9 0.4 1.2 7.9 1.8 2.0 4.0 0.0 1.5 0.0 210.6 0.1 0.8 0.7 0.0 0.5 1.1 1.1 0.3 3.7 0.0 0.0 2.3 0.2 0.3 0.6 2.0 3.8 1.3 1.0 0.4 0.5 2.0 3.3 0.5 0.5 0.0 0.0 0.6 0.9 0.0 1.0 1.8 0.0 0.8 9.6 1.0 6.0 0.5 1.0 1.4 0.0 0.9 0.2 0.2 0.6 0.8 211.8 0.0 0.2 0.3 0.5 0.5 3.9 1.3 0.0 0.5 0.2 0.6 1.0 STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Cell type enriched" "Detected in many" 4 "Hepatic stellate cells: 745.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Group enriched" "Detected in some" 46 "HUVEC TERT2: 103.1;NB-4: 146.9;TIME: 128.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" 194.2 160.4 41.0 50.4 42.9 13.8 84.5 41.4 58.3 54.4 62.8 87.7 29.6 45.3 8.5 29.2 79.3 25.8 74.6 41.9 44.4 85.6 102.1 104.7 12.9 50.0 48.4 32.2 32.2 5.0 52.0 55.4 53.7 57.6 31.0 0.6 45.7 16.0 25.9 24.0 95.1 33.8 43.0 439.5 53.2 21.0 65.3 6.8 55.1 4.6 8.2 105.7 48.6 47.8 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.2 0.2 0.6 0.0 0.0 1.8 0.1 0.0 0.1 0.0 103.1 0.1 0.3 0.1 0.0 0.0 0.0 146.9 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.0 0.0 128.8 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 9.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 41.0 42.9 41.4 58.3 41.9 44.4 50.0 48.4 53.7 43.0 65.3 47.8 31.3 0.0 3.8 0.0 5.5 6.0 0.6 0.0 1.8 1.0 1.5 2.7 2.4 11.5 0.0 3.7 0.0 1.7 1.9 0.0 0.0 0.0 0.5 0.4 0.5 43.0 1.2 21.5 0.3 0.0 2.0 3.3 0.5 0.3 18.3 0.0 745.0 19.7 130.7 0.0 0.3 0.0 0.0 185.4 30.3 2.9 4.4 147.0 12.4 30.0 21.9 0.5 2.1 0.5 0.1 0.0 0.0 20.3 2.0 0.2 0.0 0.8 0.0 0.1 19.7 2.0 1.4 0.9 2.2 1.5 4.8 2.2 2.3 0.5 0.0 0.2 STARD13 "ARHGAP37, DLC2, GT650, LINC00464" ENSG00000133121 "StAR related lipid transfer domain containing 13" Q9Y3M8 13 33103137-33350630 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Astrocytes: 212.5;Excitatory neurons: 120.7;Inhibitory neurons: 135.6;Microglial cells: 167.7;Oligodendrocyte precursor cells: 212.6;Oligodendrocytes: 470.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 50.2;TIME: 36.0;WM-115: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039535, HPA058867" Supported NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA039535: AB_10965929, HPA058867: AB_2683839" "unprognostic (7.42e-2)" "unprognostic (6.71e-2)" "unprognostic (1.99e-1)" "unprognostic (4.99e-2)" "unprognostic (1.17e-2)" "unprognostic (1.47e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" "unprognostic (1.48e-1)" "unprognostic (7.13e-3)" "unprognostic (3.42e-2)" "unprognostic (4.66e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.36e-1)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (5.29e-2)" 16.0 10.9 10.0 5.6 13.2 0.3 11.1 8.7 10.9 16.6 13.4 28.0 4.8 14.8 5.3 7.2 10.4 10.8 12.5 12.6 8.1 8.4 6.1 12.5 2.5 11.1 11.9 7.2 10.8 16.9 4.3 24.6 9.6 9.0 6.8 1.8 6.4 8.1 5.4 5.3 7.0 15.7 8.4 7.4 11.2 2.8 11.7 1.4 20.4 6.3 1.4 14.0 9.6 13.6 11.4 1.6 3.4 2.4 6.8 16.0 0.6 21.2 26.2 17.4 10.8 0.9 4.0 0.1 2.8 10.2 10.7 10.4 1.5 7.5 22.0 10.0 3.6 5.2 3.9 5.2 5.7 0.0 4.6 13.3 4.3 19.7 24.0 9.7 17.1 0.1 0.0 1.7 50.2 3.3 0.0 0.0 2.2 1.2 5.7 0.2 16.6 0.1 10.6 3.2 0.1 5.5 3.2 8.0 2.6 3.0 18.5 4.7 36.0 8.7 9.3 22.0 11.0 2.9 0.0 0.1 7.0 0.1 40.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 10.0 13.2 8.7 10.9 12.6 8.1 11.1 11.9 9.6 8.4 11.7 13.6 30.5 28.9 15.1 212.5 0.1 2.4 2.8 1.1 4.0 5.3 8.6 5.1 19.8 7.2 2.0 9.2 0.0 9.4 4.2 11.8 0.0 7.7 1.2 5.5 26.6 18.4 6.7 0.0 120.7 2.2 3.7 18.8 10.7 6.4 5.1 6.2 17.9 10.7 16.7 5.0 135.6 4.4 0.0 8.8 6.8 1.4 7.2 10.8 14.2 167.7 0.8 1.1 0.0 212.6 470.9 5.5 4.3 7.5 4.7 4.4 3.4 2.1 6.3 0.4 13.1 15.6 33.1 0.1 0.3 1.0 2.3 7.5 0.6 31.1 5.4 1.5 STK25 "SOK1, YSK1" ENSG00000115694 "Serine/threonine kinase 25" O00506 2 241492670-241509730 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 489.9;tongue: 213.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047147 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA047147: AB_10966137" "unprognostic (1.75e-1)" "unprognostic (8.29e-2)" "prognostic unfavorable (6.03e-4)" "unprognostic (3.42e-2)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (3.91e-8)" "unprognostic (6.16e-2)" "unprognostic (7.15e-3)" "unprognostic (1.11e-1)" "unprognostic (2.58e-3)" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-1)" "unprognostic (3.19e-1)" "unprognostic (4.58e-1)" 53.2 50.6 48.2 37.1 48.9 47.0 52.8 35.8 56.7 59.8 27.8 59.8 36.2 62.9 24.0 62.6 60.5 32.9 69.1 50.4 47.1 56.5 50.0 49.6 36.7 37.5 40.9 59.4 70.3 45.9 65.3 38.7 43.3 55.4 30.5 28.9 48.7 40.2 489.9 53.1 50.5 42.1 30.7 61.6 58.7 48.7 46.4 38.5 71.9 213.8 31.8 60.8 56.7 41.2 75.2 46.9 91.1 114.0 109.9 75.9 140.1 122.3 81.8 90.9 103.4 52.3 64.4 28.5 33.7 163.9 82.3 62.9 130.2 132.9 109.9 107.0 136.4 79.7 98.3 136.6 99.3 48.7 59.0 110.1 93.9 88.3 70.3 111.1 208.7 102.6 125.2 24.6 168.8 78.6 73.0 75.9 127.9 69.5 66.3 121.1 116.2 42.6 79.5 62.4 152.8 70.2 59.4 44.2 77.0 102.7 35.7 85.2 245.7 68.2 83.0 79.1 88.3 50.3 12.1 48.8 66.0 39.6 79.1 17.0 16.3 12.9 17.3 15.5 16.3 15.9 15.9 18.5 15.0 16.9 12.3 11.8 5.8 24.6 19.7 11.8 23.3 12.6 48.2 48.9 35.8 56.7 50.4 47.1 37.5 40.9 43.3 30.7 46.4 41.2 43.6 22.4 41.4 23.2 19.7 25.5 29.0 29.7 19.9 48.7 33.2 39.4 36.3 42.9 24.0 25.8 27.1 82.7 19.8 35.2 27.4 46.0 13.8 18.5 28.4 52.7 35.4 48.6 29.8 34.2 80.7 35.1 36.7 25.4 25.4 40.8 45.7 21.5 45.1 32.0 26.1 40.0 20.3 27.3 25.7 14.4 32.6 20.8 19.6 21.5 47.0 58.9 18.6 16.1 27.5 36.9 74.5 39.9 15.8 37.1 43.4 46.1 16.2 41.1 46.0 41.7 35.3 90.2 54.7 31.7 30.4 52.4 25.4 53.2 44.9 29.9 STX6 ENSG00000135823 "Syntaxin 6" O43752 1 180972712-181023121 "Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038557, HPA038558" Approved Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Nucleoplasm "HPA038557: AB_2676082, HPA038558: AB_10672716" "unprognostic (1.11e-2)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (9.09e-3)" "unprognostic (2.23e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (6.24e-5)" "unprognostic (2.12e-1)" "unprognostic (6.12e-2)" "unprognostic (4.48e-3)" "unprognostic (4.18e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (1.93e-8)" "unprognostic (2.59e-1)" "unprognostic (1.59e-1)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" 9.5 7.4 13.7 11.2 14.9 2.7 9.2 15.9 17.9 9.5 11.6 7.9 7.5 8.2 7.7 17.5 7.4 7.1 5.8 15.6 13.5 8.7 4.8 11.3 10.9 13.8 13.7 8.2 4.1 7.4 4.5 11.5 12.6 7.2 8.1 8.1 8.0 6.7 4.0 12.8 7.6 8.7 13.2 9.3 7.9 5.6 14.1 17.2 11.4 4.9 14.1 14.2 11.2 16.6 16.9 18.6 18.0 24.1 18.5 21.7 30.3 21.2 27.3 16.4 13.9 17.4 16.5 17.0 28.7 23.4 10.2 29.4 16.5 37.4 19.0 12.3 12.1 11.4 14.2 17.2 18.4 16.4 14.1 19.9 33.6 27.6 28.3 29.3 33.6 15.7 21.3 11.8 22.0 24.2 15.9 15.4 28.2 21.0 9.2 13.7 22.0 24.7 19.6 41.7 25.5 27.0 22.2 42.3 23.9 30.7 25.8 14.9 28.0 22.4 11.8 21.2 17.3 19.8 11.8 12.3 11.0 15.8 13.5 2.6 1.6 2.1 0.7 1.3 0.8 0.7 1.1 1.1 2.2 0.7 1.4 0.9 1.4 0.2 1.1 0.7 1.4 0.6 13.7 14.9 15.9 17.9 15.6 13.5 13.8 13.7 12.6 13.2 14.1 16.6 13.9 16.0 18.6 32.3 11.8 48.9 21.3 19.0 41.5 12.8 16.0 11.7 6.4 2.8 13.7 18.4 6.2 25.7 15.8 10.5 11.7 10.7 8.9 19.4 16.6 23.0 23.4 16.0 54.7 9.8 24.9 12.7 19.4 22.7 12.0 12.7 14.6 4.8 26.4 8.4 38.0 11.1 16.2 26.1 28.0 11.8 8.4 31.9 7.2 23.4 25.2 6.7 15.5 50.3 30.7 14.9 13.9 13.2 10.0 22.2 10.2 11.5 13.3 11.4 6.6 8.2 12.2 5.6 15.4 47.8 37.6 20.5 14.0 16.4 10.6 22.8 STYK1 "DKFZp761P1010, NOK, SuRTK106" ENSG00000060140 "Serine/threonine/tyrosine kinase 1" Q6J9G0 12 10618923-10674318 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.1;stomach 1: 17.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.6;Excitatory neurons: 20.6;Gastric mucus-secreting cells: 15.3;Paneth cells: 12.6;Proximal enterocytes: 10.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Immune cell enriched" "Detected in some" 7 "NK-cell: 12.5" "Lineage enriched" "Detected in many" 7 "NK-cells: 12.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 28.7;HDLM-2: 17.5;HMC-1: 18.3;HUVEC TERT2: 25.5;TIME: 23.8" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Not detected" "Not detected" "HPA040468, HPA048569" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" Nucleoplasm "HPA040468: AB_2676998, HPA048569: AB_2680446" "unprognostic (2.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (3.11e-2)" "unprognostic (3.35e-2)" "unprognostic (6.85e-2)" "unprognostic (5.08e-3)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (1.70e-14)" "unprognostic (5.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" 0.4 0.3 1.2 1.8 3.0 1.1 3.9 0.0 5.2 1.9 0.0 15.9 2.4 0.5 1.2 7.3 2.2 3.5 0.1 3.6 0.0 0.6 0.3 1.3 1.4 0.0 0.0 0.3 0.3 0.0 2.4 0.7 0.0 11.6 17.1 0.9 6.7 0.9 0.1 2.8 11.2 0.6 0.0 0.9 17.5 0.2 0.0 0.2 0.4 0.0 2.5 5.1 3.3 0.3 4.8 0.2 0.0 0.6 0.0 0.0 1.3 7.3 0.7 3.5 3.4 2.6 28.7 0.3 4.7 1.8 4.5 1.4 1.6 8.0 7.4 17.5 0.4 1.0 2.4 0.2 0.0 2.2 18.3 0.4 0.4 5.1 0.3 0.5 25.5 0.2 0.3 0.3 8.1 3.1 0.2 1.3 4.2 11.8 2.0 0.1 2.0 0.3 2.5 14.6 0.9 0.1 4.5 4.9 0.0 6.7 3.5 0.6 23.8 1.0 3.8 0.5 0.8 0.0 1.0 0.2 3.5 0.2 5.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.0 0.1 12.5 0.0 0.0 0.0 0.3 1.2 3.0 0.0 5.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 2.2 0.0 0.0 0.3 0.8 3.1 1.2 0.6 3.3 2.0 0.7 1.5 3.3 0.0 0.0 0.1 1.8 19.6 0.0 0.5 0.2 7.3 0.5 0.4 4.2 0.8 20.6 0.2 0.6 0.2 15.3 4.5 1.3 6.3 0.0 0.0 0.0 0.0 1.6 8.9 2.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 6.2 0.0 0.5 5.9 12.6 0.0 0.9 4.7 10.6 0.0 8.8 0.4 0.0 1.2 0.2 0.2 0.8 3.1 1.0 0.3 1.9 0.0 6.9 5.5 SULT1B1 ST1B2 ENSG00000173597 "Sulfotransferase family 1B member 1" O43704 4 69721167-69787961 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.4;stomach 1: 44.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 298.2;Gastric mucus-secreting cells: 61.7;Paneth cells: 153.4;Proximal enterocytes: 234.3;Undifferentiated cells: 76.4" "Group enriched" "Detected in some" 11 "colorectal cancer: 7.6;liver cancer: 2.6;pancreatic cancer: 5.5;stomach cancer: 5.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 10.7;neutrophil: 32.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 32.0" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 110.9;OE19: 26.3;TIME: 36.2;U-2197: 31.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA002107 Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA002107: AB_2666542" "unprognostic (9.58e-2)" "unprognostic (4.05e-2)" "unprognostic (1.66e-2)" "unprognostic (1.16e-1)" "unprognostic (2.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.50e-1)" "unprognostic (4.77e-2)" "unprognostic (5.14e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "unprognostic (3.27e-1)" "unprognostic (1.15e-3)" "unprognostic (1.89e-1)" "unprognostic (1.06e-2)" "unprognostic (6.93e-2)" "unprognostic (5.46e-2)" 3.0 0.7 2.3 10.7 4.3 5.5 2.1 8.0 6.8 1.5 2.5 69.9 99.4 2.0 2.4 2.0 1.5 1.5 1.9 3.2 1.8 1.9 23.8 2.5 4.2 0.9 0.9 3.0 0.8 0.9 0.1 1.3 2.0 2.5 62.2 3.9 0.8 1.4 1.2 1.3 95.3 5.1 0.3 9.7 44.9 1.2 2.0 3.0 2.7 2.3 7.5 1.6 0.9 5.6 0.7 0.6 0.8 0.8 1.8 1.9 1.2 0.8 0.4 0.3 0.3 0.7 0.7 1.3 0.7 0.8 1.0 1.1 0.1 0.2 0.7 1.5 1.0 1.0 1.2 0.5 2.7 1.3 1.3 12.3 0.2 0.3 0.5 1.1 110.9 1.6 0.6 2.5 1.0 0.7 0.6 1.0 0.8 26.3 0.4 0.6 3.7 0.8 0.2 1.8 1.3 0.8 0.5 0.3 0.5 0.7 1.6 0.6 36.2 1.0 1.7 31.5 0.6 1.9 1.0 0.6 0.4 3.3 1.3 10.7 4.8 1.4 1.0 2.7 0.3 0.1 1.5 0.4 2.7 0.2 4.9 2.5 32.0 2.9 3.4 0.2 0.9 2.6 2.3 4.3 8.0 6.8 3.2 1.8 0.9 0.9 2.0 0.3 2.0 5.6 1.3 19.2 20.8 0.3 0.9 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 8.4 0.0 0.0 0.0 4.9 298.2 0.0 0.3 0.1 1.2 0.1 2.2 33.7 2.7 0.1 4.4 0.2 1.8 61.7 0.2 16.4 0.2 2.9 45.1 0.3 0.0 0.1 42.6 0.0 24.9 1.8 0.0 0.0 9.4 0.0 3.7 15.4 0.0 11.3 0.0 0.1 18.2 153.4 0.0 1.0 0.2 234.3 1.5 12.8 0.0 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.3 6.7 0.1 76.4 0.1 SUSD5 KIAA0527 ENSG00000173705 "Sushi domain containing 5" O60279 3 33150043-33218810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Excitatory neurons: 15.4;Inhibitory neurons: 10.5;Oligodendrocyte precursor cells: 61.3;Sertoli cells: 32.9;Smooth muscle cells: 29.0" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 31.1;HUVEC TERT2: 78.5;LHCN-M2: 30.4;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052788 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA 17000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "HPA052788: AB_2681948" "unprognostic (1.81e-1)" "unprognostic (1.52e-2)" "unprognostic (5.84e-3)" "unprognostic (5.52e-3)" "unprognostic (1.39e-3)" "unprognostic (4.05e-2)" "unprognostic (3.72e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" "unprognostic (2.24e-2)" "unprognostic (1.69e-1)" "unprognostic (2.15e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-3)" "unprognostic (6.45e-2)" "unprognostic (8.46e-2)" "unprognostic (1.89e-2)" 4.6 1.4 2.9 0.9 3.0 0.1 1.9 2.2 4.6 6.3 4.4 1.7 0.8 4.6 2.2 1.3 5.2 5.5 1.5 3.1 4.4 1.5 0.5 1.7 2.3 3.4 3.4 3.8 0.6 1.0 0.8 0.2 3.4 1.3 1.2 0.6 0.7 6.3 1.6 1.9 1.9 4.8 3.8 2.5 1.8 2.1 4.7 0.1 3.2 3.3 5.3 1.5 2.4 3.5 0.0 1.1 1.2 0.7 1.7 0.2 0.1 9.6 3.4 31.1 10.5 0.1 0.0 0.0 8.8 2.5 9.5 0.1 13.7 4.5 12.9 0.3 15.3 0.0 2.0 0.0 0.2 0.1 0.1 1.3 2.4 19.9 3.9 15.2 78.5 0.0 0.0 0.1 30.4 0.0 0.0 0.1 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.0 1.0 0.1 0.1 2.5 0.7 1.8 1.9 31.3 0.0 14.4 1.2 4.7 0.0 0.7 0.0 0.3 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.9 3.0 2.2 4.6 3.1 4.4 3.4 3.4 3.4 3.8 4.7 3.5 0.1 0.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 2.2 0.5 0.0 0.0 15.4 0.0 0.1 1.4 0.0 0.9 0.0 0.2 0.4 0.0 0.0 3.3 10.5 0.0 0.0 2.1 2.0 0.3 0.0 0.1 1.8 0.0 0.0 0.5 0.0 61.3 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 32.9 3.6 29.0 0.1 2.6 0.1 1.0 0.0 0.2 0.1 0.0 0.1 SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.6;naive B-cell: 84.8" "Group enriched" "Detected in all" 7 "B-cells: 84.8;granulocytes: 48.6;monocytes: 29.6" "Cell line enhanced" "Detected in many" "Daudi: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" 39.3 10.4 12.8 37.5 13.7 20.9 31.9 13.6 15.9 22.6 17.2 15.0 15.4 17.8 10.4 17.8 16.3 22.0 16.2 12.2 14.1 17.2 10.0 24.9 66.1 16.7 13.6 10.2 15.0 19.4 5.7 39.0 16.7 14.1 12.8 3.9 18.0 15.3 9.8 26.4 20.3 19.7 16.5 59.5 15.9 4.8 14.3 17.3 22.3 14.7 75.3 31.2 17.6 16.5 40.6 22.2 30.8 0.1 62.9 54.6 54.0 43.4 52.6 40.3 44.1 24.7 31.3 161.0 41.6 83.5 57.9 47.7 37.9 24.2 51.6 14.8 15.2 42.6 25.7 12.1 35.2 33.3 76.2 38.4 29.6 29.5 52.3 32.6 124.4 20.2 3.9 0.6 42.4 6.4 10.0 16.1 28.4 10.7 11.3 23.6 28.9 4.7 33.6 106.1 1.5 15.5 41.3 52.6 35.2 42.9 20.9 25.1 143.6 70.3 25.1 59.4 41.2 4.2 12.4 111.5 27.9 36.6 29.3 19.7 5.7 48.6 1.2 13.5 0.5 80.6 1.4 1.1 8.2 84.8 1.2 1.3 1.1 7.9 29.6 2.3 4.2 5.4 12.8 13.7 13.6 15.9 12.2 14.1 16.7 13.6 16.7 16.5 14.3 16.5 154.0 67.3 60.8 33.0 183.7 35.6 68.1 40.1 36.5 3.4 35.1 28.3 17.6 22.8 57.7 20.2 0.0 82.6 9.9 11.3 13.7 47.4 1.6 66.5 18.6 136.0 13.1 9.7 9.0 21.6 128.0 39.1 15.8 71.6 137.8 10.3 53.2 7.2 65.0 26.9 14.5 8.7 18.3 61.9 50.8 2.9 29.8 58.5 28.4 77.8 88.8 9.2 6.2 22.1 22.4 37.0 15.1 34.6 20.7 63.0 22.4 11.7 50.9 2.3 19.7 46.2 35.5 5.5 10.8 17.4 31.3 140.1 15.5 33.4 9.0 78.8 SYNJ2 INPP5H ENSG00000078269 "Synaptojanin 2" O15056 6 157981863-158099176 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 116.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 102.1;Glandular and luminal cells: 114.2;Oligodendrocytes: 502.1;Pancreatic endocrine cells: 140.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 133.4;TIME: 109.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031575 Approved Approved Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Microtubules Cytosol "HPA031575: AB_10604101" "prognostic unfavorable (2.63e-4)" "unprognostic (1.94e-2)" "unprognostic (7.61e-2)" "unprognostic (1.25e-2)" "unprognostic (1.48e-2)" "unprognostic (7.68e-2)" "unprognostic (1.24e-1)" "unprognostic (7.06e-2)" "unprognostic (2.91e-1)" "unprognostic (7.29e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.02e-6)" "unprognostic (1.66e-2)" "unprognostic (3.75e-2)" "unprognostic (1.75e-1)" "unprognostic (9.45e-2)" 4.2 5.8 26.1 6.2 69.9 20.0 8.0 58.6 42.0 4.5 1.9 10.6 7.1 7.6 10.5 7.7 5.5 9.4 10.7 22.5 32.4 8.4 4.9 4.5 5.9 98.1 74.7 3.6 8.1 1.5 4.1 3.5 78.9 6.9 10.4 2.3 16.5 5.8 7.2 4.3 6.8 7.7 57.8 4.2 8.5 9.4 58.2 6.5 5.2 9.5 6.5 11.0 4.6 116.2 16.4 56.6 4.5 7.3 3.4 11.2 24.2 29.8 60.4 35.0 41.1 28.7 13.5 0.5 19.8 57.9 133.4 15.4 10.1 18.5 40.1 22.9 9.3 31.8 29.8 30.9 6.5 10.9 32.6 5.9 9.9 53.3 12.4 47.1 61.7 16.4 24.7 6.5 16.1 7.6 14.0 12.2 5.1 51.4 31.2 6.0 19.1 13.4 11.8 18.8 34.8 2.0 22.7 14.2 5.9 17.2 10.9 7.1 109.7 25.8 26.8 61.4 36.5 2.5 7.8 0.4 49.2 17.5 18.4 3.0 0.6 0.5 0.9 0.3 1.9 1.0 1.3 0.8 0.6 2.0 1.1 0.8 4.3 1.0 0.4 0.5 1.2 0.5 26.1 69.9 58.6 42.0 22.5 32.4 98.1 74.7 78.9 57.8 58.2 116.2 17.2 3.2 3.3 5.2 15.4 21.7 19.9 7.5 14.2 2.4 25.4 18.4 13.9 21.5 8.6 18.4 0.0 7.7 12.8 20.0 3.9 59.0 35.5 48.5 13.7 26.4 17.4 5.5 102.1 35.2 5.0 16.6 34.1 114.2 5.1 37.7 7.9 5.2 2.0 0.0 10.1 14.8 10.2 2.2 17.6 56.5 1.2 12.5 10.6 7.5 6.9 1.6 16.5 8.5 502.1 140.2 7.1 6.4 13.5 50.6 13.1 1.7 14.4 0.6 0.0 7.3 18.9 0.9 1.1 11.5 17.2 15.9 17.1 2.2 15.7 36.2 SYNPO KIAA1029 ENSG00000171992 Synaptopodin Q8N3V7 5 150601080-150659207 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 369.6;skeletal muscle: 1296.3;tongue: 502.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 264.7;Distal enterocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Lineage enriched" "Detected in single" 10 "B-cells: 1.0" "Cell line enhanced" "Detected in many" "BEWO: 88.4;EFO-21: 72.8;HUVEC TERT2: 72.7;TIME: 178.0;U-87 MG: 152.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033265, HPA034631, CAB037325, HPA071347" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Actin filaments" "CAB033265: AB_2201163, CAB037325: , HPA034631: AB_10669994, HPA071347: AB_2732179" "unprognostic (2.09e-2)" "unprognostic (7.72e-3)" "unprognostic (3.95e-2)" "unprognostic (2.78e-3)" "unprognostic (3.07e-2)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-2)" "unprognostic (1.90e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (1.53e-6)" "unprognostic (1.23e-1)" "unprognostic (5.72e-2)" "unprognostic (2.21e-2)" "unprognostic (6.35e-2)" 91.8 112.1 103.5 21.3 60.7 0.3 48.6 0.0 88.9 23.2 0.8 37.4 31.4 38.7 20.9 31.0 30.8 32.2 369.6 91.2 5.2 60.6 38.5 72.1 10.6 18.2 8.5 34.6 32.9 17.1 21.6 23.8 5.2 46.0 17.5 10.0 21.6 29.1 1296.3 15.4 39.6 38.9 20.6 38.9 34.9 17.0 5.1 6.6 31.1 502.1 11.1 56.8 22.3 34.9 0.5 24.2 0.2 0.3 3.5 3.2 88.4 13.8 18.9 4.6 3.7 21.6 9.7 0.1 72.8 19.9 29.2 8.9 0.1 13.5 1.9 0.2 0.2 0.0 37.4 4.7 19.6 0.0 0.9 3.7 21.3 5.2 3.7 27.5 72.7 0.2 0.2 0.2 4.4 1.6 0.1 0.7 2.8 9.3 11.6 0.5 0.7 0.2 3.4 1.9 8.5 39.3 19.9 21.6 0.7 31.1 1.6 6.6 178.0 17.4 53.2 0.4 3.6 0.8 0.2 1.3 152.5 0.3 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.5 60.7 0.0 88.9 91.2 5.2 18.2 8.5 5.2 20.6 5.1 34.9 51.1 35.3 12.2 1.3 4.8 4.6 3.0 32.6 1.8 1.9 6.4 2.5 264.7 27.1 17.0 7.3 2.1 14.8 0.5 70.5 0.0 43.7 1.7 0.4 0.4 56.3 13.8 2.7 22.5 34.5 6.0 19.9 4.6 0.5 0.0 40.9 62.8 40.0 2.1 0.0 5.7 8.4 2.0 10.8 5.1 3.4 2.8 0.9 5.4 6.5 24.0 7.2 0.0 2.5 1.3 35.6 24.4 27.8 0.6 5.7 52.6 4.4 7.6 0.8 46.0 18.0 29.2 1.2 0.8 1.4 2.3 25.9 1.6 8.6 11.8 3.6 TACC1 ENSG00000147526 "Transforming acidic coiled-coil containing protein 1" O75410 8 38728186-38853028 "Predicted intracellular proteins" "Cell cycle, Cell division" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 554.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 34.8;granulocytes: 31.5;monocytes: 14.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017041, HPA024702, HPA056841" Approved Approved Cytosol NA NA 47000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB017041: , HPA024702: AB_1857723, HPA056841: " "unprognostic (1.83e-2)" "unprognostic (3.07e-1)" "unprognostic (2.18e-1)" "unprognostic (8.31e-2)" "unprognostic (6.55e-2)" "unprognostic (5.30e-2)" "unprognostic (1.79e-1)" "unprognostic (1.15e-1)" "unprognostic (2.47e-1)" "unprognostic (7.85e-2)" "unprognostic (1.63e-1)" "unprognostic (5.94e-2)" "prognostic favorable (1.06e-5)" "unprognostic (1.03e-3)" "unprognostic (2.84e-2)" "unprognostic (2.15e-2)" "unprognostic (1.18e-1)" 151.8 31.5 32.8 39.5 41.0 68.4 67.7 23.2 36.3 73.8 19.0 76.8 21.5 84.0 14.1 70.5 64.0 47.5 42.4 27.0 25.9 51.6 23.8 67.7 41.9 28.6 34.9 35.9 44.5 29.6 14.1 74.4 27.6 54.8 44.0 15.9 19.1 75.5 20.3 19.4 40.3 90.9 25.6 61.2 38.7 29.2 37.2 27.1 34.4 56.4 34.9 58.6 36.8 49.3 39.4 74.2 53.2 16.6 55.9 38.9 34.8 50.1 64.4 46.8 47.6 34.6 5.9 40.1 29.9 49.5 40.5 36.7 32.0 22.7 96.5 28.8 12.1 155.5 22.8 22.4 65.8 31.4 69.0 71.2 20.6 76.2 24.1 48.5 169.8 47.5 16.4 97.9 143.0 29.2 74.4 17.9 7.6 63.5 35.0 16.7 120.3 7.1 15.9 38.2 3.8 4.2 40.6 41.5 33.9 31.6 19.3 23.9 138.0 56.5 34.3 72.8 40.9 50.5 35.5 35.2 51.4 35.7 69.8 13.7 11.7 15.7 6.0 10.5 6.5 2.0 4.0 5.0 7.6 2.3 3.2 3.6 31.5 3.8 14.3 34.8 3.4 5.8 32.8 41.0 23.2 36.3 27.0 25.9 28.6 34.9 27.6 25.6 37.2 49.3 554.0 218.0 152.9 67.9 66.7 35.2 55.5 9.3 148.0 35.2 14.3 25.1 53.9 191.6 32.7 46.0 62.6 66.2 122.9 30.0 119.3 176.4 4.3 34.9 51.2 251.0 37.8 79.3 109.1 60.2 64.3 147.5 25.0 79.0 115.8 42.1 350.5 39.2 79.0 109.4 73.8 121.2 6.1 90.9 158.7 11.5 168.4 128.8 40.9 203.3 87.1 59.8 51.5 44.2 134.3 47.5 44.2 206.1 73.7 62.4 3.4 23.5 7.7 44.2 190.7 150.0 223.3 42.9 62.3 45.5 18.9 94.0 81.5 43.4 48.7 40.0 TANK "I-TRAF, TRAF2" ENSG00000136560 "TRAF family member associated NFKB activator" Q92844 2 161136908-161236230 "Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010345, HPA037675, HPA037676" Approved Supported Nucleoli,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" Cytosol Nucleoli "CAB010345: AB_2199871, HPA037675: AB_2675600, HPA037676: AB_2675601" "unprognostic (1.14e-2)" "unprognostic (9.68e-2)" "unprognostic (1.53e-1)" "unprognostic (5.27e-2)" "unprognostic (3.98e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.71e-1)" "unprognostic (2.98e-2)" "unprognostic (4.16e-2)" "unprognostic (1.06e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (2.78e-6)" "unprognostic (2.13e-2)" "unprognostic (2.00e-1)" "unprognostic (5.69e-3)" "unprognostic (2.30e-2)" 42.9 36.2 20.9 46.2 23.6 84.2 57.7 22.1 24.7 30.5 25.3 32.4 28.0 30.7 27.0 29.8 35.0 43.0 27.1 20.1 24.1 29.1 66.5 39.7 52.8 24.0 25.5 30.8 22.9 27.8 19.7 36.9 23.5 24.6 35.8 32.1 26.6 24.7 52.3 26.7 29.1 32.5 21.4 43.2 30.2 22.3 21.9 42.1 36.4 43.3 51.4 49.0 25.0 25.1 39.2 24.5 31.7 36.3 91.3 124.9 45.2 58.0 86.4 39.3 57.7 30.8 50.5 53.1 38.7 67.6 28.2 27.5 19.2 43.4 59.5 126.6 20.5 29.8 22.5 79.1 72.4 51.1 32.2 98.3 66.6 59.6 46.6 73.5 101.7 32.0 30.5 68.7 77.7 29.3 31.4 50.7 18.2 40.9 21.5 17.9 45.5 35.2 86.3 62.1 26.4 30.7 37.4 40.6 60.4 43.2 17.5 64.9 108.2 50.4 29.3 25.7 34.0 46.6 46.1 80.9 66.9 40.3 40.8 122.2 71.4 97.1 36.0 78.5 55.9 63.8 58.8 53.1 66.5 66.7 39.9 39.6 189.4 42.4 94.0 43.4 100.7 55.0 20.9 23.6 22.1 24.7 20.1 24.1 24.0 25.5 23.5 21.4 21.9 25.1 34.7 57.7 79.6 82.3 108.9 59.9 106.3 82.7 21.6 32.7 73.0 71.5 27.3 42.9 69.2 46.0 12.5 43.1 54.8 50.4 60.7 58.8 18.0 47.2 42.3 46.7 47.4 63.8 49.9 40.5 82.9 67.8 28.5 52.4 59.5 17.0 28.2 58.1 45.6 21.9 60.9 29.3 71.2 71.5 194.0 10.0 52.8 106.8 72.9 120.9 177.7 33.5 40.2 63.3 87.4 56.0 43.9 26.4 57.1 81.8 34.4 46.5 66.2 37.4 26.3 52.1 40.3 54.3 33.9 29.3 60.9 134.9 109.3 33.0 32.2 158.4 TAX1BP3 TIP-1 ENSG00000213977 "Tax1 binding protein 3" O14907 17 3662895-3668679 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.9;Ductal cells: 351.0;Exocrine glandular cells: 385.9;Pancreatic endocrine cells: 505.8;Paneth cells: 362.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 164.3;granulocytes: 217.8;monocytes: 78.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046410, HPA063078" Approved Approved "Nucleoli fibrillar center,Vesicles,Actin filaments" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli fibrillar center" "Vesicles, Actin filaments" "HPA046410: AB_2679656, HPA063078: AB_2684937" "unprognostic (6.15e-2)" "unprognostic (6.46e-3)" "unprognostic (3.37e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.68e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.80e-2)" "unprognostic (5.45e-3)" "unprognostic (5.19e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (7.90e-4)" "unprognostic (5.12e-2)" "unprognostic (2.10e-1)" "unprognostic (2.10e-3)" "unprognostic (1.92e-1)" 107.3 131.8 62.7 49.2 78.5 16.5 94.4 67.9 67.3 192.9 48.2 108.5 108.8 128.1 33.6 258.5 84.4 90.9 194.8 57.3 58.8 115.0 39.7 94.9 39.3 72.5 73.3 95.9 80.4 23.5 30.9 53.2 69.9 91.7 77.4 3.7 109.7 105.6 28.7 120.4 119.6 70.3 66.2 52.3 136.5 51.2 65.2 44.6 63.6 33.4 49.0 102.8 160.1 80.6 183.1 319.1 68.4 38.5 219.2 175.6 81.3 223.6 184.5 234.0 136.7 135.9 144.5 19.1 159.1 290.8 77.2 282.6 39.1 205.3 90.8 50.7 64.4 25.9 75.8 106.6 191.1 4.3 37.7 267.6 322.5 145.1 68.9 165.3 266.0 50.1 9.6 14.4 280.1 169.4 52.2 15.1 65.9 116.7 112.6 50.0 41.8 16.3 248.6 141.2 14.7 43.2 276.2 116.2 39.4 67.5 125.3 23.2 269.6 195.3 75.2 154.9 230.2 5.7 2.6 5.5 117.4 30.0 190.3 217.8 65.4 120.4 26.9 78.9 22.2 29.2 25.0 26.6 58.7 25.3 17.3 22.7 73.8 20.0 73.6 164.3 36.7 53.3 62.7 78.5 67.9 67.3 57.3 58.8 72.5 73.3 69.9 66.2 65.2 80.6 51.5 60.9 25.8 0.0 19.0 95.3 79.7 229.3 99.6 1.6 51.0 28.2 41.5 92.9 107.6 99.3 0.0 124.7 68.5 395.9 88.0 351.0 16.2 12.8 27.3 77.0 24.6 21.4 0.0 385.9 145.3 72.6 43.8 16.1 26.6 21.2 75.3 11.1 69.8 5.0 0.0 120.0 71.2 35.2 73.2 10.5 174.6 64.0 113.8 0.0 85.5 19.8 26.8 0.0 0.0 505.8 362.8 209.9 5.8 89.0 279.2 185.3 26.8 2.6 39.5 44.1 78.6 8.6 12.8 94.5 76.0 155.6 16.1 92.0 103.0 107.9 TBC1D9 "GRAMD9, KIAA0882, MDR1" ENSG00000109436 "TBC1 domain family member 9" Q6ZT07 4 140620782-140756385 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 91.6" "Cancer enriched" "Detected in all" 7 "breast cancer: 85.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.9" "Group enriched" "Detected in many" 37 "B-cells: 5.9;dendritic cells: 3.2;monocytes: 1.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000262, HPA006503" Uncertain Approved Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 35: Glandular cells - Unknown function" Cytosol "HPA000262: AB_2665956, HPA006503: AB_2667604" "unprognostic (1.41e-1)" "unprognostic (1.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.49e-2)" "unprognostic (3.00e-1)" "unprognostic (1.22e-2)" "unprognostic (9.17e-2)" "unprognostic (2.11e-3)" "unprognostic (2.64e-1)" "unprognostic (2.66e-1)" "unprognostic (2.96e-3)" "unprognostic (6.77e-2)" "prognostic favorable (1.61e-6)" "unprognostic (2.17e-2)" "unprognostic (1.11e-1)" "unprognostic (6.72e-2)" "unprognostic (2.16e-2)" 18.2 9.2 7.2 15.2 7.9 2.0 48.7 22.5 9.4 12.9 35.2 7.3 8.2 8.3 7.8 9.1 10.0 13.8 8.5 8.4 15.3 15.7 12.6 16.3 15.1 7.9 9.6 15.9 9.1 9.8 6.3 20.5 15.4 14.6 6.6 21.0 8.8 21.3 2.2 3.2 12.8 7.7 6.4 33.7 16.8 3.3 12.9 5.6 5.8 6.9 19.4 15.8 7.1 3.3 0.9 11.9 10.9 9.4 26.0 24.3 22.3 15.3 16.3 10.8 13.7 2.4 10.4 0.1 9.5 19.9 13.4 2.4 13.7 10.8 10.1 0.0 7.7 7.0 8.5 10.4 9.4 0.9 1.1 20.1 17.7 9.4 37.2 31.2 30.3 3.7 0.0 0.0 10.2 12.0 1.6 0.1 1.7 12.7 10.4 7.7 17.9 18.1 12.3 22.0 16.0 11.4 15.8 27.4 10.5 18.4 6.4 0.4 47.7 28.3 8.5 18.6 13.3 0.0 0.0 0.1 17.2 1.3 15.7 0.0 1.7 0.0 0.0 1.3 0.0 5.9 0.0 0.0 2.9 2.9 0.0 0.0 0.0 0.0 0.5 3.2 0.0 0.7 7.2 7.9 22.5 9.4 8.4 15.3 7.9 9.6 15.4 6.4 12.9 3.3 49.4 54.5 9.3 4.6 42.1 4.6 10.6 21.4 4.0 35.4 91.6 39.4 8.1 17.2 15.1 55.2 4.2 14.1 14.0 8.3 7.9 13.6 0.5 49.4 20.9 32.6 7.7 0.4 54.8 17.2 4.7 15.1 8.2 61.4 0.0 8.0 17.2 23.9 18.3 10.1 66.2 6.6 24.4 39.3 30.3 1.3 13.1 44.8 8.8 78.7 39.5 43.5 1.0 27.6 2.6 12.2 5.8 26.7 25.0 16.3 6.1 5.7 15.9 7.6 0.0 2.8 11.1 0.8 1.7 10.4 3.8 43.2 3.7 16.0 3.1 16.0 TBCEL "LRRC35, MGC10233" ENSG00000154114 "Tubulin folding cofactor E like" Q5QJ74 11 121024072-121090775 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 104.0;Oligodendrocytes: 39.4;Plasma cells: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA038593, HPA038594" Approved Uncertain Cytosol NA NA 22000 "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "HPA038593: AB_10669647, HPA038594: AB_2676103" "unprognostic (9.06e-3)" "unprognostic (3.42e-2)" "unprognostic (2.65e-1)" "unprognostic (2.29e-1)" "unprognostic (5.80e-2)" "unprognostic (3.13e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-2)" "unprognostic (1.27e-2)" "unprognostic (1.06e-2)" "unprognostic (4.20e-2)" "unprognostic (3.14e-1)" "unprognostic (8.55e-2)" "unprognostic (3.07e-3)" "unprognostic (1.86e-1)" "unprognostic (1.66e-2)" "unprognostic (1.02e-1)" 7.4 7.6 10.7 5.9 14.2 5.6 9.0 14.4 11.5 7.2 15.0 7.4 5.4 8.5 9.6 5.7 6.2 7.7 9.8 8.5 11.0 8.3 15.1 9.6 7.5 10.5 10.5 9.2 6.3 16.5 7.9 10.8 9.8 9.0 5.9 8.3 7.2 12.3 6.1 5.1 5.8 9.6 10.2 8.4 6.0 14.8 14.2 7.2 10.3 8.2 7.4 6.6 4.7 13.6 6.2 5.8 9.8 8.5 17.5 16.5 7.5 11.5 14.2 8.7 12.7 6.0 9.7 7.6 17.3 14.3 8.4 1.6 10.8 3.8 11.4 9.1 8.0 13.2 4.5 6.0 21.6 9.4 8.8 18.2 12.8 8.4 9.1 8.8 14.4 4.3 3.9 14.3 12.3 4.2 3.9 7.8 5.8 0.2 5.6 3.3 14.3 3.5 11.7 3.8 5.2 12.0 11.3 11.7 7.9 8.3 11.3 7.9 18.9 19.2 4.2 7.8 6.4 5.5 4.3 4.0 2.7 0.1 7.3 0.0 0.2 0.1 0.3 0.3 0.4 0.1 0.4 0.4 0.2 0.2 0.4 0.3 0.1 0.6 0.2 0.4 0.2 0.2 10.7 14.2 14.4 11.5 8.5 11.0 10.5 10.5 9.8 10.2 14.2 13.6 9.4 6.4 11.3 15.7 7.8 2.9 1.8 2.0 2.8 9.0 4.4 2.9 10.3 7.2 1.7 7.3 14.6 1.7 3.4 2.0 1.9 4.7 11.3 9.3 8.2 8.0 3.6 104.0 34.1 2.6 1.9 7.0 1.5 3.7 1.3 6.7 13.2 20.7 3.1 8.4 32.9 2.5 4.1 6.7 2.8 5.8 9.3 4.3 10.6 20.6 10.1 5.5 6.2 36.2 39.4 3.3 1.0 9.8 42.7 2.7 2.0 4.3 8.4 9.2 0.0 14.8 6.0 14.9 6.0 3.7 1.7 1.4 3.7 6.8 2.3 1.2 TCAF2 "FAM115C, FAM139A, FLJ40722, GATD9" ENSG00000170379 "TRPM8 channel associated factor 2" A6NFQ2 7 143620952-143730409 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.2;Hepatocytes: 12.3;Syncytiotrophoblasts: 15.7;T-cells: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 10.6;HUVEC TERT2: 11.6;TIME: 18.5;U-87 MG: 13.8" "HPA038756, HPA038758" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cell Junctions" "HPA038756: AB_10960427, HPA038758: AB_10960353" "unprognostic (6.59e-2)" "unprognostic (4.99e-2)" "unprognostic (2.34e-2)" "unprognostic (8.86e-3)" "prognostic unfavorable (9.53e-5)" "unprognostic (1.89e-1)" "unprognostic (3.11e-2)" "unprognostic (4.47e-2)" "unprognostic (2.36e-1)" "unprognostic (2.04e-2)" "unprognostic (3.98e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.17e-6)" "unprognostic (7.19e-2)" "unprognostic (4.02e-2)" "unprognostic (5.41e-3)" "unprognostic (2.85e-2)" 2.1 1.9 1.5 4.0 1.5 4.1 5.8 4.6 3.4 4.0 0.0 1.2 1.0 1.7 0.8 9.2 1.9 2.2 1.2 1.5 1.9 2.6 4.5 3.7 4.2 2.2 2.5 2.6 2.0 2.1 2.6 5.2 2.5 2.8 1.1 3.2 3.7 1.2 0.7 4.3 2.4 1.5 0.7 2.8 2.0 1.6 1.7 3.3 1.3 0.7 3.4 2.8 5.9 3.2 5.5 0.3 0.1 0.2 1.0 1.0 2.0 1.5 3.1 0.7 2.2 0.1 0.3 0.2 2.1 1.3 0.5 0.8 0.1 3.0 2.3 10.6 0.5 0.8 0.6 0.1 1.2 0.3 0.4 2.9 1.3 0.3 0.9 2.1 11.6 0.7 3.0 5.1 4.3 0.8 0.6 0.8 0.2 5.0 2.7 0.4 2.1 2.4 0.0 1.9 0.1 0.1 0.5 4.3 0.2 0.8 1.9 0.2 18.5 1.3 0.9 5.5 0.4 7.7 2.6 0.1 13.8 0.4 3.2 5.7 0.2 0.2 2.9 0.2 3.1 1.9 4.8 3.1 0.2 1.8 4.2 3.3 0.9 2.2 0.2 0.7 5.6 1.2 1.5 1.5 4.6 3.4 1.5 1.9 2.2 2.5 2.5 0.7 1.7 3.2 0.5 0.0 1.8 0.0 4.5 0.0 1.3 0.0 3.4 0.7 5.6 3.4 0.4 0.0 1.8 0.0 0.0 16.2 5.6 0.2 0.0 0.9 1.0 0.8 1.4 3.5 0.0 0.4 3.7 0.4 4.9 2.4 2.6 1.3 2.5 0.3 0.7 12.3 2.0 0.0 3.6 0.2 0.0 1.6 0.0 1.1 1.8 1.8 0.0 0.0 0.4 2.1 7.2 1.5 0.1 1.3 0.1 0.7 5.0 2.1 2.1 0.4 0.0 0.1 0.0 2.3 1.1 3.5 2.0 4.9 0.0 15.7 9.1 0.8 0.4 1.1 TCTEX1D4 ENSG00000188396 "Tctex1 domain containing 4" Q5JR98 1 44805893-44807351 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 21.6;fallopian tube: 10.2" "Group enriched" "Detected in some" 9 "Endometrial ciliated cells: 94.5;Respiratory ciliated cells: 129.4" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "neutrophil: 7.9" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.9" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 1.7;TIME: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA062652 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "HPA062652: AB_2684818" "unprognostic (3.12e-1)" "unprognostic (3.13e-1)" "unprognostic (1.81e-1)" "prognostic favorable (1.58e-4)" "unprognostic (5.28e-2)" "unprognostic (3.59e-2)" "unprognostic (2.85e-2)" "unprognostic (2.26e-1)" "unprognostic (3.85e-1)" "unprognostic (1.69e-2)" "unprognostic (1.26e-2)" "unprognostic (4.92e-2)" "unprognostic (4.70e-3)" "unprognostic (2.86e-1)" "unprognostic (2.20e-1)" "unprognostic (1.59e-1)" "unprognostic (7.83e-3)" 1.1 2.0 0.7 1.2 1.0 2.4 0.4 1.1 2.1 1.1 21.6 0.4 0.4 1.3 2.2 0.7 10.2 1.8 0.6 0.9 1.4 0.6 0.6 2.8 0.3 5.1 4.0 0.4 0.9 0.4 0.8 0.1 3.0 0.3 0.1 0.0 1.1 0.3 0.4 0.6 0.5 0.1 2.6 0.4 1.0 0.4 3.9 0.0 0.9 0.2 0.0 0.4 0.3 3.0 0.5 0.9 0.3 0.0 0.0 0.0 1.0 0.7 0.0 0.0 0.0 0.4 0.7 0.0 0.7 0.0 0.7 0.8 0.0 0.0 0.0 1.1 0.0 0.1 0.8 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.7 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.2 0.5 0.9 0.0 0.0 1.8 0.1 0.7 0.2 0.3 0.7 0.4 0.0 0.2 0.2 0.2 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.2 0.7 1.0 1.1 2.1 0.9 1.4 5.1 4.0 3.0 2.6 3.9 3.0 0.2 0.0 0.5 0.0 0.3 0.3 0.4 11.4 0.0 0.0 0.6 0.8 0.2 1.5 10.6 1.8 0.0 0.2 0.1 0.9 0.0 1.2 0.0 94.5 0.9 0.4 0.0 0.0 0.0 4.0 0.2 0.4 0.0 1.5 0.0 0.2 0.0 1.2 0.8 0.0 0.0 1.7 10.2 1.2 0.9 0.1 0.3 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 2.4 0.0 0.0 0.4 2.3 1.3 129.4 0.0 0.0 0.8 3.8 0.1 0.6 0.0 0.0 0.3 0.3 0.5 0.6 0.5 TDRD10 DKFZp434M202 ENSG00000163239 "Tudor domain containing 10" Q5VZ19 1 154502219-154548147 "Cancer-related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 55.6" "Group enriched" "Detected in some" 5 "Early spermatids: 61.8;Late spermatids: 89.0;Spermatocytes: 103.7" "Cancer enhanced" "Detected in many" "testis cancer: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.0;TIME: 1.4" "Not detected" "Not detected" HPA054327 Approved Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA054327: AB_2682452" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.33e-3)" "unprognostic (9.69e-3)" "unprognostic (5.80e-3)" "unprognostic (2.99e-1)" "unprognostic (5.97e-3)" "unprognostic (2.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.00e-3)" "unprognostic (1.61e-1)" "unprognostic (1.34e-3)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "prognostic favorable (8.04e-5)" "unprognostic (1.62e-1)" 11.1 4.5 3.7 0.5 3.7 0.1 6.8 3.1 3.7 5.1 3.3 2.8 0.7 4.2 2.3 2.4 6.5 1.6 7.6 3.3 3.2 3.5 4.5 8.1 0.8 3.2 3.5 10.1 0.9 0.9 2.6 1.7 3.3 3.9 1.3 0.1 1.8 1.2 1.9 2.3 3.5 1.8 3.2 8.9 1.9 55.6 3.7 0.5 11.0 1.4 0.4 3.9 3.6 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.7 3.1 3.7 3.3 3.2 3.2 3.5 3.3 3.2 3.7 3.1 10.0 3.2 6.7 4.9 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.5 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.8 0.0 0.1 8.2 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 1.3 0.7 6.1 0.4 0.4 0.0 0.5 0.0 0.0 4.0 2.1 89.0 2.5 1.0 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.4 103.7 16.5 0.1 0.3 0.0 0.0 0.1 0.0 0.0 TECPR1 "DKFZP434B0335, FLJ23419, FLJ90593, KIAA1358" ENSG00000205356 "Tectonin beta-propeller repeat containing 1" Q7Z6L1 7 98214624-98252232 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "pancreas: 84.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Rod photoreceptor cells: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021061 Approved Supported Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "HPA021061: AB_1847687" "unprognostic (8.10e-3)" "unprognostic (7.89e-2)" "unprognostic (9.05e-3)" "unprognostic (5.00e-3)" "unprognostic (2.03e-1)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (1.45e-2)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "prognostic favorable (8.12e-4)" "unprognostic (2.48e-1)" "unprognostic (2.54e-1)" "unprognostic (1.38e-1)" "unprognostic (3.24e-1)" "unprognostic (9.46e-2)" "unprognostic (6.12e-2)" 8.4 7.0 11.7 10.4 12.3 6.1 8.0 6.5 12.5 6.4 4.7 8.5 9.2 6.8 3.0 9.8 6.9 5.7 9.9 12.7 12.9 7.7 9.2 13.3 11.8 11.8 11.2 5.7 84.9 3.1 16.7 8.6 12.7 11.6 5.0 10.2 18.9 3.8 9.1 5.9 10.8 4.7 8.5 18.6 18.3 4.6 11.5 9.5 9.6 5.0 6.7 6.8 6.6 8.2 4.4 6.1 8.4 18.3 7.2 4.3 6.2 9.1 5.0 7.1 8.7 5.8 5.4 3.6 14.4 10.6 8.8 2.8 5.7 4.2 3.0 8.8 8.0 5.3 9.4 5.3 8.5 6.5 9.9 7.5 3.4 6.9 5.3 6.6 25.2 15.1 3.6 15.0 5.4 7.2 9.4 6.8 3.3 8.6 5.9 7.8 8.5 17.7 5.4 4.8 15.0 16.9 5.4 14.9 8.5 6.1 4.8 9.2 26.0 6.7 11.5 17.4 7.6 17.6 9.8 1.9 14.0 5.6 12.5 2.5 2.9 0.9 2.2 3.2 1.3 1.8 2.9 1.7 1.8 1.6 4.8 4.2 3.5 1.0 4.9 2.4 3.0 2.3 11.7 12.3 6.5 12.5 12.7 12.9 11.8 11.2 12.7 8.5 11.5 8.2 32.2 9.6 18.4 18.3 12.3 2.3 2.2 3.7 1.8 37.1 7.0 5.8 11.2 7.2 7.0 5.5 106.3 6.0 10.9 16.0 1.9 6.4 2.1 6.9 5.5 22.9 29.3 2.1 21.1 13.4 9.8 7.2 35.7 8.1 8.2 11.0 21.0 8.5 13.7 32.0 17.8 22.9 10.2 20.5 4.0 2.2 7.2 14.2 1.8 16.9 19.5 11.4 14.4 10.1 10.1 11.9 10.3 3.4 17.4 4.1 10.8 3.6 7.7 66.7 0.0 7.5 7.4 5.5 4.5 7.1 1.8 3.4 16.0 9.0 10.0 2.9 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295068 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Intestinal goblet cells: 1.0;Plasma cells: 2.8;Spermatocytes: 1.5;Spermatogonia: 4.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 438.0;fHDF/TERT166: 429.4;HBEC3-KT: 929.2;hTEC/SVTERT24-B: 560.1;LHCN-M2: 252.2;TIME: 799.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: AB_2682554, HPA065897: AB_2685576" "unprognostic (1.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.24e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-3)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (9.16e-4)" "unprognostic (8.84e-11)" "unprognostic (1.92e-1)" "unprognostic (2.15e-1)" "unprognostic (3.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 213.2 438.0 3.2 0.0 173.9 31.7 59.4 0.3 0.1 3.0 0.2 429.4 0.1 0.1 1.0 929.2 29.1 0.0 1.7 0.1 0.0 0.4 0.1 0.5 1.2 0.0 22.9 560.1 6.8 1.3 1.5 1.8 2.9 0.2 252.2 0.4 0.2 9.4 2.9 0.1 1.3 2.1 0.0 5.4 23.9 0.5 0.2 2.1 0.1 0.0 0.2 0.0 0.1 0.3 799.9 0.0 0.0 0.0 0.0 0.9 0.5 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 TFPI "EPI, LACI, TFI, TFPI1" ENSG00000003436 "Tissue factor pathway inhibitor" P10646 2 187464230-187565760 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 272.3;placenta: 191.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2284.2;Hepatic stellate cells: 872.4;Syncytiotrophoblasts: 879.2" "Cancer enhanced" "Detected in all" "liver cancer: 22.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 3.3;neutrophil: 1.3;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 6 "dendritic cells: 2.7;granulocytes: 3.3" "Cell line enhanced" "Detected in many" "HHSteC: 386.2;HUVEC TERT2: 742.5;LHCN-M2: 459.9;TIME: 451.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA005575, CAB020842" Supported "Secreted to blood" NA NA 58100000 87000000 "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB020842: , HPA005575: AB_1080290" "unprognostic (8.75e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (7.95e-2)" "unprognostic (4.99e-2)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (3.05e-1)" "unprognostic (5.63e-2)" "unprognostic (3.86e-3)" "unprognostic (9.22e-2)" "unprognostic (2.43e-2)" "unprognostic (2.72e-2)" "unprognostic (7.05e-2)" "unprognostic (3.39e-3)" "unprognostic (4.05e-2)" "unprognostic (4.49e-2)" "unprognostic (5.81e-2)" 67.5 12.6 2.6 20.5 3.4 8.2 52.3 4.9 5.8 41.5 7.4 23.3 52.5 25.7 18.5 33.3 35.6 57.6 38.5 4.1 2.2 56.3 272.3 126.7 33.3 6.8 2.5 26.5 25.0 7.1 6.1 191.2 3.9 15.7 27.4 4.5 15.0 12.8 26.8 19.8 41.8 30.7 3.7 20.7 19.2 6.9 3.6 11.1 36.2 42.8 17.7 52.9 29.8 3.2 38.9 24.7 29.3 0.8 224.3 267.7 0.7 66.0 156.3 42.7 65.1 22.6 192.6 0.7 27.3 52.7 74.7 2.1 15.9 3.6 110.3 1.9 7.6 12.3 73.8 197.3 386.2 0.9 0.4 123.1 5.1 232.8 61.9 93.4 742.5 0.7 31.2 0.7 459.9 35.4 4.6 0.7 22.9 0.8 68.8 0.3 40.2 0.3 72.9 1.4 0.3 0.5 56.7 2.1 3.5 95.8 0.7 0.2 451.4 30.6 29.0 61.4 13.5 1.1 1.7 0.4 239.4 0.6 35.4 3.3 0.2 0.2 0.2 0.1 0.1 0.4 0.1 0.0 0.2 0.5 0.2 0.2 1.3 0.5 0.1 2.7 0.1 2.3 2.6 3.4 4.9 5.8 4.1 2.2 6.8 2.5 3.9 3.7 3.6 3.2 99.2 35.3 335.5 1.3 4.4 20.8 2.9 33.5 4.6 0.6 16.1 9.1 7.0 173.0 102.5 38.6 0.0 59.5 4.8 0.5 13.7 140.0 41.5 7.3 74.2 287.1 105.0 43.1 0.7 273.1 2284.2 283.0 12.2 5.3 13.9 1.5 872.4 382.1 50.2 1.7 0.2 11.3 158.7 63.7 41.3 15.2 171.8 21.9 26.6 13.1 33.7 33.1 1.0 0.0 0.1 157.6 34.1 70.0 9.5 8.0 36.6 109.4 45.2 1.1 216.9 141.2 127.8 2.7 0.5 10.2 18.5 879.2 8.1 30.6 18.5 16.7 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 230.0 56.1 16.5 73.8 12.9 29.4 145.7 13.8 19.3 90.0 30.6 96.0 44.2 69.1 18.2 44.9 69.6 91.9 95.2 10.6 13.4 67.9 59.1 148.0 70.1 17.6 16.5 26.6 52.0 59.0 16.9 81.6 16.7 44.1 54.1 2.1 49.2 60.8 31.1 39.1 77.7 107.2 17.3 111.1 63.4 7.8 21.5 49.7 91.8 62.2 60.7 98.0 55.1 17.2 16.6 100.2 5.3 0.1 313.6 472.3 15.9 83.9 116.1 28.5 27.7 22.9 86.6 2.2 298.2 117.2 32.2 33.3 4.0 125.4 42.0 7.0 8.9 10.1 10.7 104.5 128.5 14.9 76.6 430.0 93.6 126.3 114.4 117.0 296.0 10.9 1.8 0.0 381.7 1.3 16.2 10.5 2.2 75.7 39.8 14.1 36.4 2.1 113.5 40.5 0.1 5.6 24.9 6.1 22.0 6.6 0.0 14.0 418.6 134.7 33.2 61.4 32.0 2.8 0.3 12.5 80.1 16.1 55.8 9.0 3.0 11.5 3.4 3.1 3.3 4.5 4.8 3.3 2.6 6.4 16.6 7.3 13.1 1.9 8.0 6.6 0.7 3.8 16.5 12.9 13.8 19.3 10.6 13.4 17.6 16.5 16.7 17.3 21.5 17.2 391.5 144.2 99.7 0.7 77.0 37.3 18.9 23.5 39.9 5.1 23.7 24.1 84.5 50.1 39.5 27.6 0.0 6.8 85.3 10.5 3.9 13.1 2.5 28.3 57.5 236.4 8.4 20.4 0.4 15.8 5.1 129.2 39.3 30.8 29.8 0.7 478.0 55.5 30.4 0.0 1.0 12.4 22.4 147.0 58.0 3.8 32.9 67.9 30.2 170.5 47.5 0.2 56.7 6.0 2.4 37.6 12.1 47.4 37.5 8.6 13.6 7.2 14.7 1.2 32.9 60.8 53.4 0.3 1.2 8.0 30.5 3.7 68.2 1.7 14.5 10.8 TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127385-38166578 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 432.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.5;Cytotrophoblasts: 311.1;Ductal cells: 226.7;Endometrial stromal cells: 459.1;Hepatic stellate cells: 408.0;Hepatocytes: 205.7;Pancreatic endocrine cells: 326.5;Syncytiotrophoblasts: 374.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 1546.7;EFO-21: 505.5;hTERT-RPE1: 994.3;HUVEC TERT2: 695.3;TIME: 924.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Yes No 1700000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Plasma membrane" "CAB002598: , HPA021019: AB_1858247, HPA029518: AB_10603133" "unprognostic (7.80e-2)" "unprognostic (1.51e-1)" "unprognostic (5.22e-2)" "unprognostic (1.40e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-3)" "unprognostic (3.29e-2)" "unprognostic (9.78e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (6.99e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (1.60e-2)" "unprognostic (1.93e-2)" "unprognostic (6.70e-2)" "unprognostic (6.40e-2)" 105.9 45.1 23.0 68.4 22.3 3.2 30.3 22.9 29.5 432.0 53.0 30.6 29.8 266.3 28.3 37.3 217.7 127.7 394.9 21.4 23.0 76.7 244.1 288.5 18.0 25.4 22.5 40.6 25.6 19.3 95.9 234.3 26.0 88.7 20.8 2.1 9.8 56.6 63.9 4.0 63.7 159.0 24.4 32.7 62.3 3.9 30.6 15.4 36.3 33.4 10.3 154.2 87.8 24.8 65.0 47.5 0.2 1.8 47.3 5.1 24.0 95.5 45.2 0.7 1.8 78.4 1546.7 0.1 505.5 1.0 105.4 1.7 0.1 221.7 3.4 0.7 0.2 10.3 2.6 35.0 191.9 0.0 0.5 5.2 0.4 40.2 0.3 994.3 695.3 0.0 21.4 0.1 16.0 0.3 0.0 0.6 0.8 0.9 4.6 0.0 0.1 0.3 69.0 0.0 0.0 1.3 224.4 0.2 7.6 31.6 2.2 0.6 924.2 1.6 57.6 7.8 46.3 0.0 0.6 0.8 60.7 0.1 18.4 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 22.3 22.9 29.5 21.4 23.0 25.4 22.5 26.0 24.4 30.6 24.8 58.0 9.6 18.3 0.0 7.4 0.5 10.4 41.0 0.6 0.0 8.5 8.8 204.5 31.5 55.3 14.7 2.1 311.1 0.1 11.7 3.9 226.7 3.2 16.7 459.1 183.8 0.0 74.5 0.1 145.7 38.6 37.7 0.5 13.1 2.5 2.8 408.0 205.7 54.4 0.0 0.1 1.8 6.1 23.7 2.1 5.0 1.2 35.5 0.0 28.1 6.5 0.4 0.0 0.0 0.3 326.5 1.1 6.0 0.0 68.6 63.0 27.6 23.6 0.5 0.0 5.2 49.1 0.4 4.0 0.9 0.0 374.2 3.9 2.1 3.3 26.4 THBS1 "THBS, THBS-1, TSP, TSP-1, TSP1" ENSG00000137801 "Thrombospondin 1" P07996 15 39581079-39599466 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion, Unfolded protein response" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 279.5;Granulosa cells: 228.3;Macrophages: 598.0;Smooth muscle cells: 283.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 15.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 2610.2;HUVEC TERT2: 2494.4;LHCN-M2: 1863.4;TIME: 3552.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 20.6" "CAB033678, HPA059756" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 16000000000 1400000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB033678: AB_793044, HPA059756: AB_2684121" "unprognostic (1.72e-2)" "unprognostic (9.55e-3)" "unprognostic (7.49e-2)" "unprognostic (3.31e-1)" "unprognostic (4.34e-2)" "unprognostic (1.03e-3)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (6.40e-2)" "unprognostic (9.16e-2)" "prognostic unfavorable (8.47e-5)" "prognostic unfavorable (8.50e-4)" "unprognostic (1.00e-1)" "unprognostic (9.25e-3)" "unprognostic (1.48e-3)" 364.3 72.5 1.7 394.0 3.7 114.7 95.1 2.1 11.3 66.7 27.3 166.4 24.8 161.3 3.5 49.1 142.6 275.2 98.3 2.2 2.1 70.9 129.4 309.2 32.3 10.8 4.4 76.3 69.1 7.0 26.8 99.0 10.8 89.8 85.6 0.4 137.3 12.0 16.2 35.4 83.5 243.6 0.9 79.8 150.5 2.2 14.3 12.0 34.0 4.3 7.1 396.3 36.2 2.1 171.9 62.7 49.0 17.8 199.4 233.9 0.7 1025.7 861.6 283.6 185.5 185.0 135.7 1.0 348.4 2610.2 54.4 621.0 2.2 516.1 145.0 43.4 0.5 46.6 35.0 46.9 44.4 0.3 13.2 524.9 37.2 237.2 535.1 1123.6 2494.4 1.6 1.5 1.7 1863.4 14.7 0.8 3.6 8.9 17.7 20.3 0.7 125.7 1.3 430.6 472.6 0.6 0.4 300.7 16.4 18.5 60.8 178.6 3.3 3552.9 972.6 221.0 1141.1 1146.6 2.4 1.8 2.0 33.0 0.8 1064.4 0.3 8.7 15.7 0.7 0.8 2.7 0.0 0.4 0.5 0.5 0.1 0.1 0.1 1.5 7.8 0.1 0.4 0.0 10.5 1.7 3.7 2.1 11.3 2.2 2.1 10.8 4.4 10.8 0.9 14.3 2.1 19.0 25.6 19.6 0.7 4.9 95.7 131.2 37.6 181.6 0.1 66.8 69.8 48.7 18.6 19.9 69.9 6.2 1.9 8.2 144.5 0.0 52.1 0.2 64.9 127.7 79.2 3.6 0.0 0.9 127.5 2.5 279.5 15.8 38.2 162.7 228.3 44.6 7.4 6.3 0.0 1.3 46.4 48.8 105.9 97.9 0.3 1.8 598.0 39.2 13.1 5.9 0.1 3.1 0.0 0.1 183.9 55.1 0.4 5.9 79.2 8.5 48.3 11.9 1.5 6.6 59.0 283.8 0.2 0.3 51.8 51.0 2.1 19.5 10.8 67.8 42.1 THSD1 TMTSP ENSG00000136114 "Thrombospondin type 1 domain containing 1" Q9NS62 13 52377167-52416373 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 22.0;Astrocytes: 25.5;Basal respiratory cells: 16.5;Endothelial cells: 29.9;Hepatic stellate cells: 17.2;Microglial cells: 17.8;Spermatocytes: 18.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 19.9;HBEC3-KT: 19.9;hTCEpi: 19.0;hTERT-HME1: 19.5;HUVEC TERT2: 40.6;LHCN-M2: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012611, CAB020796" Uncertain Supported Cytosol "Intracellular and membrane" No No 1400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB020796: , HPA012611: AB_1857990" "unprognostic (1.21e-1)" "unprognostic (7.54e-3)" "unprognostic (3.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.31e-1)" "unprognostic (1.54e-2)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.87e-2)" "unprognostic (3.35e-1)" "unprognostic (6.10e-3)" "unprognostic (1.55e-1)" "unprognostic (3.05e-3)" "unprognostic (8.44e-2)" "unprognostic (1.31e-1)" "unprognostic (3.35e-2)" "unprognostic (4.90e-2)" 10.0 2.0 7.9 1.0 7.4 0.2 8.7 5.5 8.5 5.3 4.5 2.8 0.7 5.2 2.8 3.1 5.1 3.3 9.0 8.2 5.5 3.0 2.2 11.5 2.1 6.0 5.4 2.1 1.4 1.4 3.4 11.3 5.8 4.1 1.4 6.8 3.9 1.9 4.5 6.3 2.7 4.7 5.6 5.9 2.1 2.1 6.4 1.4 5.0 10.4 1.6 3.8 4.5 5.9 0.9 3.9 0.5 3.5 3.1 10.3 0.8 8.4 4.1 3.2 5.1 0.1 0.7 0.3 1.0 19.9 3.1 4.4 0.0 19.9 4.9 9.3 2.9 0.5 0.0 0.0 1.9 2.1 0.6 4.1 19.0 15.4 19.5 1.8 40.6 1.2 0.0 0.3 18.6 0.0 0.7 0.4 0.3 0.2 0.9 0.6 4.3 0.0 4.5 0.2 0.1 0.7 0.2 0.1 0.8 0.2 0.4 0.3 9.6 1.0 1.7 0.0 6.3 0.6 0.1 0.1 1.8 0.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 7.4 5.5 8.5 8.2 5.5 6.0 5.4 5.8 5.6 6.4 5.9 22.0 0.0 1.1 25.5 0.9 1.5 1.1 16.5 0.6 8.0 1.5 3.0 3.1 0.0 1.8 1.8 2.1 5.4 3.6 0.3 3.9 0.3 1.4 0.8 1.0 29.9 0.0 0.0 3.5 0.6 1.8 6.4 1.1 0.7 0.0 1.5 17.2 2.0 3.1 0.0 3.1 0.3 0.0 1.6 1.6 0.6 3.4 0.6 5.4 17.8 0.4 1.2 1.0 3.0 0.9 0.4 0.2 3.8 0.6 1.8 0.4 0.8 1.3 3.2 6.6 4.4 2.3 18.5 10.1 1.0 1.6 3.4 0.9 0.6 0.3 0.4 THSD4 "ADAMTSL6, FLJ13710, FVSY9334, PRO34005" ENSG00000187720 "Thrombospondin type 1 domain containing 4" Q6ZMP0 15 71096952-71783383 "Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 103.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 106.4;Basal squamous epithelial cells: 449.0;Microglial cells: 247.3;Squamous epithelial cells: 141.5" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 45.3;BJ hTERT+: 53.0;T-47d: 43.3;TIME: 66.6;U-2197: 44.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.0" "Secreted - unknown location" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.59e-1)" "unprognostic (4.38e-2)" "unprognostic (3.14e-2)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.14e-1)" "unprognostic (7.80e-2)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (3.01e-3)" 4.8 8.4 9.8 1.6 7.8 0.0 14.7 6.1 8.6 103.7 9.5 7.0 7.9 22.2 7.8 60.3 37.0 10.9 41.6 8.5 7.2 14.2 7.0 10.3 0.9 7.8 9.1 3.1 6.4 0.7 9.7 3.6 7.6 34.0 6.9 1.2 11.4 15.0 3.0 8.5 8.7 10.3 7.0 1.9 12.0 3.1 15.9 1.6 8.8 2.5 2.5 13.3 38.5 5.9 6.0 45.3 0.8 13.0 6.7 40.2 0.2 22.0 53.0 11.2 5.8 0.3 8.7 0.0 17.7 7.8 38.5 17.0 1.8 9.1 6.8 2.0 2.0 0.0 4.4 0.0 4.3 0.0 0.0 3.0 6.7 6.7 26.6 30.5 20.7 0.0 0.0 0.5 9.2 9.1 0.0 0.1 3.9 0.1 7.8 0.0 0.7 0.8 29.5 6.0 0.7 5.5 8.8 10.9 0.0 5.0 43.3 0.1 66.6 0.2 1.0 44.4 11.8 0.0 0.3 0.0 10.4 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 7.8 6.1 8.6 8.5 7.2 7.8 9.1 7.6 7.0 15.9 5.9 1.1 19.2 9.0 6.5 0.0 13.9 106.4 11.3 449.0 3.0 48.7 43.9 60.1 58.6 7.5 5.5 6.2 0.4 0.8 16.2 1.9 18.3 7.5 19.3 13.2 9.8 3.0 0.0 17.1 1.8 0.4 12.5 2.6 31.8 0.0 0.3 6.1 12.3 0.2 0.0 19.1 6.1 0.0 0.0 2.1 16.9 17.4 1.6 8.8 247.3 0.0 0.3 0.0 8.5 6.7 13.6 11.0 74.4 1.2 94.6 29.3 0.5 11.0 0.9 0.0 16.8 6.6 0.9 1.7 141.5 10.9 0.8 3.1 42.2 13.2 29.7 TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 130.8;Endothelial cells: 108.8;Hepatic stellate cells: 128.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.1;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.1;NK-cells: 2.5" "Group enriched" "Detected in some" 4 "EFO-21: 106.3;HUVEC TERT2: 238.4;TIME: 210.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 87000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" 47.0 10.1 16.6 8.1 14.8 0.9 37.8 14.6 16.9 14.0 10.1 11.2 5.2 20.4 5.3 6.5 16.0 13.3 34.2 13.1 14.2 19.8 6.7 35.3 10.1 16.4 16.5 7.5 4.2 3.2 8.0 48.6 16.8 10.8 3.1 0.4 7.4 6.5 14.0 7.9 11.0 14.1 13.9 19.9 8.8 3.0 21.1 2.1 24.2 20.7 2.9 15.1 11.8 14.8 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 106.3 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 41.9 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.7 238.4 0.0 0.0 0.0 0.0 0.0 0.0 20.4 1.3 0.0 0.1 8.1 16.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.1 210.0 1.2 0.4 0.0 0.2 0.0 0.2 0.4 0.0 0.0 3.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 16.6 14.8 14.6 16.9 13.1 14.2 16.4 16.5 16.8 13.9 21.1 14.8 130.8 0.0 4.2 0.0 0.4 2.2 0.6 0.0 1.2 0.3 1.0 0.9 4.9 1.5 1.8 0.0 0.0 0.3 0.7 0.9 0.0 0.0 2.0 0.1 0.4 108.8 0.0 2.5 0.4 0.2 0.1 3.1 0.0 0.4 20.3 0.1 128.8 1.3 0.5 0.0 0.2 0.1 0.0 5.6 3.1 2.5 2.1 1.1 1.8 29.0 0.1 0.1 1.0 1.0 1.1 0.0 0.0 0.7 0.1 0.7 0.1 0.9 3.6 0.9 0.0 2.2 2.2 0.9 0.7 0.5 1.4 0.3 2.3 0.5 0.2 0.7 TJP1 "DKFZp686M05161, MGC133289, ZO-1" ENSG00000104067 "Tight junction protein 1" Q07157 15 29699367-29968915 "Predicted intracellular proteins, Transporters" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 893.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001636, HPA001637, CAB010822" Enhanced Enhanced "Cell Junctions" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "CAB010822: , HPA001636: AB_1080762, HPA001637: AB_1080760" "unprognostic (2.11e-2)" "unprognostic (6.83e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-2)" "unprognostic (9.43e-2)" "unprognostic (1.21e-1)" "unprognostic (4.54e-2)" "unprognostic (6.71e-3)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (2.86e-3)" "unprognostic (3.54e-1)" "prognostic favorable (1.72e-4)" "unprognostic (2.85e-3)" "unprognostic (3.02e-1)" "unprognostic (5.04e-2)" "unprognostic (1.20e-1)" 37.4 16.5 22.1 4.4 35.3 1.1 30.8 21.4 24.4 33.2 17.9 30.5 7.1 42.3 16.5 60.4 27.8 12.6 37.1 22.0 22.2 24.3 18.6 34.0 5.7 26.6 28.6 22.3 30.0 13.4 16.8 31.6 25.2 20.4 9.5 10.0 29.6 10.9 22.0 27.8 19.8 17.4 20.6 13.5 25.8 29.7 30.3 3.7 24.8 5.0 10.2 23.8 35.3 42.6 62.4 36.8 29.1 18.4 17.0 31.7 28.9 18.6 21.1 18.0 20.2 59.2 22.9 0.3 24.8 24.6 21.3 47.4 20.1 23.8 19.0 0.5 14.9 0.3 22.3 24.7 57.9 0.1 0.8 16.5 15.8 21.4 39.2 23.0 38.2 0.1 24.3 12.5 14.2 32.2 0.2 0.7 21.9 23.4 14.6 0.1 35.0 0.2 28.1 33.4 12.9 16.8 39.2 12.8 16.8 42.9 13.3 0.6 54.7 14.3 23.9 12.5 25.6 4.4 4.6 0.4 17.8 0.3 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 35.3 21.4 24.4 22.0 22.2 26.6 28.6 25.2 20.6 30.3 42.6 212.1 169.9 49.2 299.7 1.6 35.8 115.2 36.4 39.3 42.4 53.7 28.6 107.2 51.5 48.6 58.8 10.4 32.3 0.8 87.7 25.4 116.0 19.1 132.2 97.0 166.0 46.0 2.7 293.8 83.7 11.3 56.6 86.6 290.7 5.7 87.7 100.3 49.1 3.8 126.2 187.3 45.4 32.6 6.1 12.1 13.7 33.8 5.2 64.0 266.1 1.6 32.8 0.0 345.3 893.8 178.3 82.0 63.9 5.9 151.4 37.8 26.0 39.2 52.4 78.9 64.1 118.7 63.0 83.9 139.2 60.1 33.7 4.1 120.8 33.1 194.6 TJP2 "DFNA51, X104, ZO-2, ZO2" ENSG00000119139 "Tight junction protein 2" Q9UDY2 9 69121264-69274615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 212.4;Rod photoreceptor cells: 267.6;Urothelial cells: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 237.5" "Low region specificity" "Detected in all" "HPA001813, CAB009228, HPA070714" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 580000 "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB009228: AB_2203583, HPA001813: AB_1080764, HPA070714: AB_2732161" "unprognostic (1.30e-1)" "unprognostic (7.69e-2)" "unprognostic (1.23e-3)" "unprognostic (7.68e-2)" "unprognostic (2.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.82e-2)" "unprognostic (3.30e-2)" "unprognostic (2.93e-3)" "unprognostic (3.60e-1)" "prognostic favorable (1.78e-14)" "unprognostic (3.29e-2)" "unprognostic (6.42e-2)" "unprognostic (8.15e-3)" "unprognostic (5.85e-2)" 44.4 14.9 35.1 11.6 45.3 12.0 30.2 44.5 42.6 16.9 25.7 39.0 54.4 19.8 13.1 45.8 23.8 24.4 35.8 38.0 45.4 44.7 64.8 47.6 9.7 52.6 39.9 37.0 21.9 57.9 5.3 18.4 52.6 24.8 35.1 122.0 37.1 21.9 14.1 35.0 49.6 16.1 55.0 5.7 58.3 32.1 39.9 32.5 44.9 15.1 23.1 55.3 22.3 66.3 237.5 6.4 24.4 25.8 92.9 90.3 108.5 37.3 26.7 54.9 29.0 31.8 106.6 33.0 37.0 20.3 31.4 158.3 33.2 79.3 75.9 115.3 20.7 34.5 22.5 165.2 28.9 13.8 59.1 71.3 65.2 43.1 32.4 19.6 143.6 9.9 19.7 24.7 34.3 36.0 5.5 2.3 49.5 194.5 50.0 23.1 26.9 2.9 192.0 194.2 8.3 14.9 13.3 111.2 3.4 55.7 37.0 7.9 196.3 44.3 48.3 32.4 38.6 23.0 5.2 0.9 48.0 19.6 16.1 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.8 0.1 35.1 45.3 44.5 42.6 38.0 45.4 52.6 39.9 52.6 55.0 39.9 66.3 2.9 44.8 22.8 76.4 2.3 65.1 79.1 26.3 4.6 212.4 4.6 1.3 38.5 40.0 33.1 3.7 35.5 27.9 2.7 74.4 0.0 32.5 3.5 7.1 1.7 36.4 11.5 10.5 10.1 24.3 25.6 15.5 64.2 9.9 5.7 0.2 27.5 104.9 5.6 18.5 13.4 45.0 36.7 14.6 28.9 6.7 29.2 8.2 28.4 22.5 9.0 111.1 1.0 21.6 82.5 44.2 65.8 13.9 5.2 115.4 73.4 1.9 51.3 267.6 0.0 4.9 13.1 19.6 18.0 40.6 64.1 43.2 3.2 0.2 50.3 244.5 TM6SF1 ENSG00000136404 "Transmembrane 6 superfamily member 1" Q9BZW5 15 83107572-83144854 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 47.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;granulocytes: 44.4;Hofbauer cells: 50.9;Kupffer cells: 37.8;Langerhans cells: 46.4;Macrophages: 45.9;Microglial cells: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 76.6;eosinophil: 195.8;neutrophil: 118.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 195.8" "Cell line enhanced" "Detected in some" "HEL: 23.2;HHSteC: 49.6;HUVEC TERT2: 27.7;JURKAT: 36.4;TIME: 68.3;U-698: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016051, HPA056857" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "HPA016051: AB_2203924, HPA056857: AB_2683259" "unprognostic (8.09e-2)" "unprognostic (1.31e-1)" "unprognostic (2.87e-2)" "unprognostic (4.67e-1)" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (6.46e-2)" "unprognostic (3.52e-3)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.80e-1)" "unprognostic (2.55e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.15e-2)" "unprognostic (4.65e-3)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" 6.5 3.9 5.4 5.2 6.0 5.3 4.6 7.7 8.8 3.3 6.3 2.6 2.0 2.8 2.1 3.1 2.8 3.7 9.6 5.2 5.6 1.9 2.3 10.7 5.7 6.8 6.0 1.7 1.2 1.8 0.9 7.8 6.6 2.1 2.6 2.8 2.9 1.3 47.3 1.8 2.6 3.9 6.9 6.2 2.1 3.6 5.4 2.2 10.4 21.8 3.0 3.8 1.5 7.6 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.3 5.6 0.0 0.2 0.0 0.3 0.1 1.0 0.0 0.3 0.0 3.7 0.0 0.0 0.0 0.3 23.2 0.0 0.0 49.6 1.6 0.1 0.2 0.0 0.0 0.1 0.3 27.7 36.4 0.9 0.0 0.4 0.0 0.0 3.0 0.6 0.0 0.0 0.0 4.2 0.0 0.1 0.4 1.2 0.3 0.2 0.0 1.9 0.5 0.0 14.9 68.3 0.6 0.9 0.1 0.3 2.1 0.0 17.0 0.1 3.4 0.1 76.6 31.7 195.8 5.0 13.4 0.0 0.3 0.5 0.8 18.9 0.9 0.1 0.8 118.1 5.0 6.4 2.6 0.0 11.8 5.4 6.0 7.7 8.8 5.2 5.6 6.8 6.0 6.6 6.9 5.4 7.6 30.5 0.0 6.0 2.9 0.9 2.4 0.1 0.4 0.6 1.6 0.5 1.8 1.2 1.5 0.8 0.0 0.0 0.3 7.5 0.0 0.0 0.2 13.1 0.6 0.2 16.7 0.0 4.4 18.7 2.0 0.4 1.5 0.0 0.3 44.4 0.0 7.9 0.1 50.9 0.0 22.4 0.0 0.0 37.8 46.4 7.4 0.9 45.9 3.6 46.9 19.4 0.5 16.5 2.0 1.9 0.4 0.0 0.0 0.7 0.1 0.0 0.0 1.4 1.3 0.0 1.4 0.6 13.1 7.5 0.1 1.7 0.3 4.2 0.1 0.0 0.1 TMEM217 "C6orf128, dJ355M6.2" ENSG00000172738 "Transmembrane protein 217" Q8N7C4 6 37212178-37258155 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.1" "Cell type enhanced" "Detected in many" "Early spermatids: 20.5;Exocrine glandular cells: 16.0;Pancreatic endocrine cells: 15.9;Spermatocytes: 55.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 7.7;HUVEC TERT2: 6.4;TIME: 17.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045432, HPA071187" Approved Nucleoli,Cytosol NA NA "Cluster 43: Testis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoli Cytosol "HPA045432: AB_2732519, HPA071187: AB_2732174" "unprognostic (7.78e-2)" "unprognostic (5.49e-2)" "unprognostic (2.22e-2)" "unprognostic (1.29e-2)" "unprognostic (7.79e-2)" "unprognostic (2.02e-1)" "unprognostic (6.77e-3)" "unprognostic (1.40e-2)" "unprognostic (3.51e-2)" "unprognostic (4.23e-4)" "unprognostic (8.22e-2)" "unprognostic (2.18e-1)" "unprognostic (5.62e-2)" "unprognostic (7.26e-2)" "unprognostic (1.33e-2)" "unprognostic (6.99e-2)" "unprognostic (1.59e-1)" 0.7 3.1 0.9 0.7 1.0 2.8 0.5 1.0 1.6 0.3 0.9 0.3 1.1 0.3 1.5 1.6 0.7 1.2 0.3 0.9 0.9 0.6 0.9 0.7 0.4 0.9 0.9 0.3 2.7 1.3 0.1 0.3 1.0 0.3 0.3 0.7 1.2 0.1 0.1 1.0 0.4 0.4 0.8 0.2 0.2 9.1 1.0 0.7 0.7 0.0 0.3 2.2 0.1 1.1 0.7 0.0 0.5 0.4 0.3 2.1 0.3 2.2 3.9 1.9 5.5 1.7 1.3 0.1 0.8 0.5 2.4 1.2 0.7 0.6 2.0 0.7 1.1 7.7 1.7 0.9 0.9 0.2 3.7 1.4 1.7 5.0 0.5 1.0 6.4 0.8 2.5 0.0 0.9 0.9 0.5 3.2 0.6 0.0 0.3 1.0 0.2 0.2 2.1 0.8 0.6 0.3 0.4 0.4 1.0 0.9 0.1 0.4 17.6 1.8 0.5 0.2 0.4 0.5 0.7 1.9 0.3 1.7 0.4 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.9 1.0 1.0 1.6 0.9 0.9 0.9 0.9 1.0 0.8 1.0 1.1 2.6 0.0 0.6 2.9 0.7 2.5 8.9 2.6 0.6 0.8 3.9 1.8 0.2 1.5 3.9 1.8 0.0 0.8 1.3 3.4 3.9 15.0 20.5 8.3 1.3 3.3 1.8 0.0 2.9 16.0 0.6 3.8 2.0 5.6 5.7 1.4 0.4 0.1 0.9 3.3 2.1 0.4 2.0 0.6 6.3 14.9 0.6 2.8 1.8 0.0 0.0 6.4 0.0 1.5 3.0 15.9 1.1 0.0 0.5 6.9 0.8 1.1 5.0 0.5 0.0 4.1 1.8 55.0 0.8 3.4 3.0 1.1 1.1 1.5 1.0 13.9 TMEM255B "FAM70B, MGC20579" ENSG00000184497 "Transmembrane protein 255B" Q8WV15 13 113759226-113816995 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 65.0;Endothelial cells: 81.5;granulocytes: 39.3;Hepatic stellate cells: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 31.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 31.2" "Cell line enhanced" "Detected in many" "HMC-1: 28.6;HUVEC TERT2: 38.8;PC-3: 39.3;RPMI-8226: 25.1;TIME: 35.9;U-87 MG: 40.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043334 Approved Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA043334: AB_10795982" "unprognostic (2.20e-1)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (4.90e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.49e-3)" "unprognostic (3.00e-2)" "unprognostic (9.39e-2)" "prognostic unfavorable (4.12e-5)" "unprognostic (4.65e-2)" "unprognostic (1.84e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" 14.2 6.1 1.3 3.7 1.3 0.7 10.6 1.1 2.2 10.1 2.1 4.0 1.6 8.4 0.3 3.9 8.1 3.6 6.6 1.6 3.7 10.1 3.4 13.2 2.4 2.1 1.3 4.3 3.1 1.6 3.5 1.0 1.7 7.0 1.4 0.4 4.2 2.2 2.9 4.2 4.8 5.0 1.4 8.2 4.3 3.3 1.9 0.8 11.2 3.9 1.8 7.5 7.1 1.5 10.3 0.0 0.6 0.0 2.8 0.0 0.1 4.8 10.7 5.5 3.5 0.4 0.2 0.2 0.1 7.7 12.5 1.5 1.1 0.7 2.3 0.1 0.9 0.3 0.4 0.0 1.4 2.9 28.6 1.8 2.3 11.7 4.6 15.7 38.8 0.6 0.1 0.2 12.0 0.2 1.5 0.9 1.0 1.6 39.3 1.8 0.8 25.1 5.4 0.5 2.2 5.1 0.2 1.5 0.1 1.0 0.6 8.2 35.9 1.6 10.3 0.6 1.7 0.0 0.0 1.9 40.6 2.7 0.3 31.2 5.4 0.7 0.0 5.5 0.0 0.9 0.0 0.0 1.5 2.8 0.0 0.0 2.7 0.0 4.0 0.0 0.0 1.4 1.3 1.3 1.1 2.2 1.6 3.7 2.1 1.3 1.7 1.4 1.9 1.5 65.0 6.4 4.8 2.3 1.9 5.9 1.2 0.9 1.2 0.9 1.1 1.7 9.1 0.0 0.2 1.8 0.0 0.1 0.3 0.0 1.9 8.2 0.8 0.3 0.8 81.5 1.2 3.2 2.7 1.7 0.1 4.7 0.0 0.2 39.3 2.3 105.0 0.7 12.9 0.0 0.1 0.2 0.0 17.4 14.6 1.1 7.8 16.3 8.8 7.5 3.4 0.5 0.0 0.0 0.6 1.3 0.1 3.0 1.4 1.7 0.0 0.1 0.5 0.8 6.6 0.9 3.6 5.1 19.1 0.2 4.7 0.0 1.8 2.1 0.3 1.0 TMEM35A "FLJ14084, NACHO, TMEM35, TUF-1" ENSG00000126950 "Transmembrane protein 35A" Q53FP2 X 101078879-101096367 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.9;intestine: 36.8;seminal vesicle: 50.9" "Cell type enriched" "Detected in some" 5 "Theca cells: 37.5" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 10.1;HUVEC TERT2: 52.5;SH-SY5Y: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048583 Enhanced Supported Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" Vesicles "Focal adhesion sites, Cytosol" "HPA048583: AB_2680451" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-2)" "unprognostic (3.02e-2)" "unprognostic (3.89e-3)" "unprognostic (2.77e-2)" "unprognostic (6.66e-3)" "unprognostic (1.05e-1)" "unprognostic (3.34e-3)" "unprognostic (9.20e-2)" "unprognostic (4.72e-2)" "unprognostic (3.49e-4)" "unprognostic (5.91e-2)" "unprognostic (1.85e-1)" "unprognostic (1.48e-2)" "unprognostic (9.37e-3)" 3.5 6.9 20.8 1.3 20.4 0.0 0.8 18.5 28.5 4.6 2.5 36.8 3.4 7.8 3.6 11.2 4.1 3.4 0.5 28.4 71.9 0.5 0.0 2.3 0.1 21.8 21.3 7.9 0.2 12.7 2.2 0.1 36.8 22.3 9.6 10.2 0.5 50.9 0.8 0.6 7.2 10.3 15.6 0.8 5.2 1.4 47.5 0.2 0.8 2.5 0.3 9.7 4.4 13.5 0.0 0.0 5.4 0.0 3.9 10.1 0.0 1.1 0.7 0.4 0.2 0.0 0.0 0.0 0.1 3.2 0.0 0.0 3.4 0.0 1.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 0.0 3.5 0.0 1.9 0.0 7.5 52.5 0.0 0.0 0.1 6.6 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 13.2 0.0 0.0 0.0 1.3 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 20.4 18.5 28.5 28.4 71.9 21.8 21.3 36.8 15.6 47.5 13.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 7.4 0.4 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.2 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 37.5 0.0 0.0 TMEM44 DKFZp686O18124 ENSG00000145014 "Transmembrane protein 44" Q2T9K0 3 194587673-194633689 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.2;Hepatic stellate cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 3.7;NK-cell: 8.1" "Group enriched" "Detected in many" 10 "granulocytes: 3.7;NK-cells: 8.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043718 Uncertain Approved Cytosol "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA043718: AB_10794662" "unprognostic (8.94e-2)" "unprognostic (1.01e-1)" "unprognostic (8.31e-3)" "unprognostic (4.53e-2)" "unprognostic (2.78e-3)" "unprognostic (9.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.17e-2)" "unprognostic (1.70e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-2)" "unprognostic (4.75e-3)" "prognostic unfavorable (6.55e-13)" "unprognostic (1.23e-2)" "unprognostic (3.36e-1)" "unprognostic (1.65e-3)" "unprognostic (5.66e-2)" 10.3 2.9 9.8 2.3 11.7 5.2 8.9 7.8 12.4 6.9 7.1 11.0 2.7 5.6 13.7 5.6 5.4 4.5 9.6 10.3 10.1 6.0 3.4 11.3 3.0 9.9 9.7 4.9 3.5 0.9 2.6 7.4 10.0 5.2 7.2 0.6 7.7 2.2 3.2 3.6 6.8 3.2 8.8 9.3 4.9 2.2 10.5 2.0 5.6 2.3 1.6 5.3 5.9 9.2 11.1 9.1 13.4 14.2 4.8 16.2 11.8 8.2 15.3 6.8 10.8 5.0 21.8 2.0 38.9 10.0 20.3 12.6 4.5 6.4 4.6 18.1 6.3 12.4 10.6 3.8 8.7 3.9 18.9 10.0 6.8 15.4 6.8 32.8 28.2 12.1 3.4 0.5 22.9 10.1 5.9 9.9 6.9 11.1 14.8 11.5 8.4 0.3 7.2 6.3 3.7 7.7 6.1 1.9 12.6 5.6 9.0 8.5 33.7 20.8 7.6 6.4 11.2 1.5 1.2 4.0 31.4 15.0 10.4 3.7 0.2 0.2 0.4 0.1 0.0 0.1 0.1 0.6 0.0 0.2 0.0 0.2 0.4 8.1 0.3 0.4 0.0 0.0 9.8 11.7 7.8 12.4 10.3 10.1 9.9 9.7 10.0 8.8 10.5 9.2 22.0 0.0 2.3 3.3 2.1 0.5 3.3 4.9 1.8 0.9 2.8 2.3 1.7 1.5 6.0 5.5 2.1 9.5 1.7 31.2 0.0 5.7 0.6 2.3 3.7 23.8 6.0 4.0 12.7 4.9 4.0 6.0 22.4 2.0 17.7 10.6 53.2 0.6 3.5 0.0 5.4 25.2 6.1 1.3 3.4 0.3 3.1 1.5 1.8 12.2 0.1 0.5 2.1 2.5 1.5 14.9 21.0 1.9 1.3 6.0 3.9 0.4 7.5 0.6 6.6 1.8 3.6 0.5 6.5 2.4 0.6 8.8 1.9 6.0 21.0 6.3 TMEM91 "DSPC3, FLJ27310, IFITMD6" ENSG00000142046 "Transmembrane protein 91" Q6ZNR0 19 41350911-41384083 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 212.0;Late spermatids: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 193.3" "Group enriched" "Detected in all" 8 "granulocytes: 193.3;monocytes: 51.9" "Cell line enhanced" "Detected in many" "HEL: 20.1;HSkMC: 20.5;TIME: 19.8" "Low region specificity" "Detected in all" HPA053240 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "HPA053240: AB_2682085" "unprognostic (3.02e-3)" "unprognostic (1.92e-2)" "unprognostic (5.13e-3)" "unprognostic (2.97e-2)" "unprognostic (1.29e-1)" "unprognostic (9.90e-2)" "unprognostic (4.70e-2)" "unprognostic (2.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.69e-3)" "prognostic favorable (3.54e-5)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.52e-7)" "unprognostic (1.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.06e-2)" 24.0 12.8 32.3 6.9 43.1 36.2 19.7 19.5 35.2 39.1 27.7 26.6 3.5 18.6 10.2 22.6 30.2 8.2 16.4 29.3 49.0 20.3 9.6 23.3 6.5 29.2 33.3 20.1 17.7 4.1 26.2 9.4 28.4 23.0 3.9 9.2 11.4 8.6 5.4 66.3 14.3 8.7 23.3 37.5 12.3 37.8 52.7 5.7 20.5 7.3 7.6 29.8 31.3 24.2 3.3 7.0 5.4 2.7 6.4 13.6 5.0 2.6 3.4 1.3 2.1 0.5 2.9 1.5 2.4 3.0 2.1 0.9 1.3 2.4 3.0 2.3 3.6 20.1 5.7 11.1 12.3 3.4 5.2 20.5 12.6 4.0 9.8 14.8 9.2 3.7 3.8 6.2 2.1 6.3 2.5 6.6 2.3 0.9 4.2 4.2 1.2 1.4 3.4 1.6 1.4 3.3 5.0 1.0 4.1 3.8 1.3 9.9 19.8 3.1 3.0 2.9 2.7 3.8 0.6 1.1 6.5 4.6 1.2 36.8 51.9 4.0 5.9 12.3 7.4 0.7 3.4 3.1 9.5 1.4 8.0 3.9 193.3 1.5 9.1 14.6 4.7 41.2 32.3 43.1 19.5 35.2 29.3 49.0 29.2 33.3 28.4 23.3 52.7 24.2 20.2 3.2 22.4 23.8 3.5 17.8 22.9 59.8 7.4 8.3 10.7 15.9 5.3 2.8 25.0 7.3 6.2 2.7 10.6 0.7 1.9 5.3 212.0 12.0 12.1 13.7 14.4 4.8 11.7 3.2 84.3 21.7 1.1 4.8 34.2 13.0 20.0 3.8 15.7 8.4 18.9 1.6 10.2 67.6 8.4 451.5 14.0 51.6 8.8 7.5 30.7 4.1 20.6 5.0 5.8 3.8 18.5 7.2 1.7 6.5 2.3 2.5 13.5 6.4 6.6 4.8 8.6 4.9 9.0 9.7 21.3 8.6 7.8 3.7 1.7 10.4 TMSB4X "TB4X, TMSB4" ENSG00000205542 "Thymosin beta 4 X-linked" P62328 X 12975110-12977227 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 30742.3;Langerhans cells: 57681.0;monocytes: 48133.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033806 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Vesicles, Cytosol" "CAB033806: AB_2256019" "unprognostic (1.60e-1)" "unprognostic (1.00e-1)" "unprognostic (4.09e-3)" "unprognostic (1.16e-3)" "unprognostic (8.72e-2)" "unprognostic (3.27e-2)" "unprognostic (7.98e-3)" "unprognostic (1.71e-2)" "unprognostic (2.75e-1)" "unprognostic (2.28e-2)" "unprognostic (1.66e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (6.20e-4)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (3.77e-2)" "unprognostic (1.98e-1)" 6173.6 4217.0 3255.7 5088.7 3773.0 8722.4 4452.0 3539.2 4521.9 3685.7 2999.1 4327.1 1776.8 3731.3 2877.9 2069.6 2709.3 4129.3 2652.4 3319.4 3573.5 3300.1 2360.4 6225.5 10448.1 4064.7 3620.0 2592.1 1852.6 483.2 1053.7 2450.2 4203.0 2335.6 3793.9 273.3 1886.8 2441.9 816.5 1962.4 3671.2 3340.7 4219.2 7935.5 4690.0 486.8 3591.8 6377.6 1648.7 1475.0 7233.8 5168.6 2907.2 4467.6 5980.6 4886.3 9387.7 14881.1 11264.5 12247.2 23.0 3083.9 8032.6 2344.3 4005.4 1016.1 4865.3 1417.1 2900.6 9443.7 4198.0 2564.2 1411.5 2072.7 3135.4 8343.4 80.9 1771.0 2621.8 12.9 2619.8 6994.8 14038.1 5755.3 2911.9 2781.9 2412.7 5704.5 14335.9 3714.1 230.0 22.0 8424.8 2121.5 8390.5 15083.5 3384.1 2853.1 3337.3 6352.0 3321.0 5858.5 14234.5 1720.4 994.2 422.9 4461.8 207.4 583.3 6898.2 5536.5 6961.4 11607.2 3383.5 1647.5 19441.4 3123.6 4432.5 3490.6 2774.8 5183.2 2860.5 2499.5 42940.3 34738.5 50992.6 21474.2 33907.1 18326.4 18757.1 23777.1 23343.2 31253.2 16919.4 19802.1 20330.2 35862.9 18444.5 37523.3 12797.6 34088.1 86809.5 3255.7 3773.0 3539.2 4521.9 3319.4 3573.5 4064.7 3620.0 4203.0 4219.2 3591.8 4467.6 6885.8 5253.2 4939.6 35.9 6293.8 8836.3 2708.7 10515.3 296.5 332.9 2318.3 1124.2 106.9 3484.4 8003.6 6882.2 22.9 283.0 9136.2 9016.2 2181.5 17304.6 142.1 2613.2 4698.0 9239.4 1765.0 1339.1 54.3 23029.4 511.7 4800.1 2728.9 5047.4 4380.4 4646.7 6638.0 1088.5 30742.3 62.2 81.0 4883.9 14806.8 20982.2 57681.0 343.6 3932.0 17648.1 6349.9 212.7 48133.8 86.7 20882.8 19.6 102.1 25113.5 5826.4 6035.9 2541.8 3272.5 6888.7 835.1 2596.4 99.4 5732.4 1018.2 5450.7 58.2 126.3 933.7 9528.5 454.8 12719.6 3874.8 3140.6 9064.0 TNFAIP8L1 MGC17791 ENSG00000185361 "TNF alpha induced protein 8 like 1" Q8WVP5 19 4639516-4655568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 31.3;liver: 34.2" "Group enriched" "Detected in many" 5 "Early spermatids: 327.0;Late spermatids: 862.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 33.9;HUVEC TERT2: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.39e-1)" "unprognostic (1.14e-2)" "unprognostic (3.70e-1)" "unprognostic (9.03e-3)" "unprognostic (1.00e-1)" "unprognostic (2.80e-2)" "unprognostic (8.39e-2)" "unprognostic (3.88e-2)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (3.70e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.28e-7)" "unprognostic (7.65e-2)" "unprognostic (8.99e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" 6.8 3.1 8.6 5.0 10.3 2.4 5.3 7.9 9.9 4.9 4.6 31.3 8.8 4.3 3.3 5.7 23.1 3.6 8.1 10.1 6.9 8.8 34.2 8.2 6.8 5.7 6.3 3.9 2.6 1.3 4.4 5.2 5.8 3.5 4.4 0.5 2.3 1.5 4.8 6.8 12.5 5.5 4.9 17.5 10.8 13.9 8.1 4.7 5.4 5.6 5.4 7.0 4.5 7.8 17.2 5.4 7.3 11.6 2.2 3.5 3.8 3.1 5.7 6.3 5.7 9.6 6.3 8.2 1.5 4.8 6.8 8.5 4.6 5.5 5.9 13.6 2.1 18.8 3.3 17.6 3.2 2.8 33.9 4.5 1.6 5.7 3.7 7.9 33.1 10.0 10.0 11.8 7.3 5.5 3.4 13.8 3.7 12.0 7.3 9.4 4.7 3.8 6.3 1.5 2.9 6.5 1.5 4.4 6.4 5.4 3.1 7.4 24.1 3.2 12.9 4.9 12.3 6.4 8.4 7.3 6.2 8.6 9.3 3.2 2.3 7.0 1.4 3.3 2.5 3.6 2.5 1.5 1.9 2.6 3.1 2.7 1.0 3.1 5.1 1.6 3.3 2.0 8.6 10.3 7.9 9.9 10.1 6.9 5.7 6.3 5.8 4.9 8.1 7.8 25.8 0.0 10.3 0.7 12.0 11.6 3.2 7.1 2.8 3.5 3.7 3.4 2.6 8.6 10.0 3.7 0.0 3.8 10.0 4.5 1.9 2.9 327.0 96.9 6.3 46.2 7.7 11.0 5.3 1.2 7.4 5.6 1.1 5.7 49.5 7.1 63.5 41.0 7.7 3.3 2.8 4.3 10.2 11.3 19.3 862.9 8.4 12.5 5.4 6.5 13.5 0.9 11.3 1.0 1.0 2.7 1.4 7.2 6.5 3.4 6.9 20.5 109.9 4.6 19.7 8.3 8.1 10.4 7.6 5.0 11.2 9.3 10.4 5.8 11.4 2.6 TNFAIP8L3 FLJ41287 ENSG00000183578 "TNF alpha induced protein 8 like 3" Q5GJ75 15 51056598-51105276 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 86.9;smooth muscle: 84.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 10.3;Inhibitory neurons: 14.4;Langerhans cells: 10.8;Smooth muscle cells: 9.3;Spermatocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;ASC TERT1: 87.8;HUVEC TERT2: 78.7;LHCN-M2: 74.5;TIME: 105.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077484 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA077484: AB_2732347" "unprognostic (1.38e-1)" "unprognostic (6.22e-2)" "unprognostic (1.12e-3)" "unprognostic (6.63e-2)" "unprognostic (2.54e-1)" "unprognostic (1.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.15e-2)" "unprognostic (4.21e-2)" "unprognostic (4.70e-3)" "unprognostic (6.54e-2)" "unprognostic (9.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (3.51e-4)" 9.4 3.8 9.2 7.1 8.3 0.8 5.7 3.5 8.2 13.7 4.3 8.6 1.6 86.9 6.0 20.4 45.6 6.2 6.3 15.3 6.6 2.7 2.4 15.5 3.9 5.5 8.5 15.9 2.4 0.8 3.0 2.0 4.8 6.8 8.6 0.3 3.9 5.4 4.7 23.1 7.9 84.8 4.3 19.9 5.8 4.4 6.6 0.9 5.4 3.5 3.2 18.6 15.1 5.6 0.1 0.4 0.1 0.2 35.0 87.8 0.4 0.3 0.1 1.0 1.6 0.1 1.0 0.1 1.5 5.0 11.2 0.1 1.2 0.8 0.4 0.1 0.7 0.0 2.4 5.9 9.1 0.3 1.9 32.5 7.1 6.7 26.8 5.8 78.7 0.1 0.1 0.1 74.5 0.9 0.0 0.6 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.1 0.1 0.1 0.9 0.5 0.6 105.5 8.0 0.5 26.5 2.3 0.4 0.0 0.1 16.7 0.1 0.1 0.9 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.6 0.3 0.2 0.2 0.0 0.0 9.2 8.3 3.5 8.2 15.3 6.6 5.5 8.5 4.8 4.3 6.6 5.6 1.2 0.0 0.5 4.6 0.0 3.3 1.1 0.4 0.0 0.1 0.2 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.3 2.3 1.7 3.9 10.3 0.0 4.5 0.4 0.0 5.8 0.0 0.1 0.0 7.1 1.8 0.3 2.9 0.0 14.4 3.3 2.0 2.9 10.8 0.7 9.0 3.5 1.8 1.0 0.6 0.1 0.0 1.0 2.6 0.1 1.5 5.3 0.1 0.4 0.0 0.1 1.3 0.2 6.6 1.6 9.3 23.7 0.8 0.3 8.4 0.0 0.1 0.1 1.5 0.5 TNFRSF10B "CD262, DR5, KILLER, TRAIL-R2, TRAILR2, TRICK2A, TRICKB" ENSG00000120889 "TNF receptor superfamily member 10b" O14763 8 23020133-23069031 "Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA023625 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA023625: AB_1847860" "unprognostic (8.43e-3)" "unprognostic (7.43e-3)" "unprognostic (3.04e-2)" "unprognostic (4.94e-3)" "unprognostic (1.13e-1)" "unprognostic (7.74e-2)" "unprognostic (2.15e-1)" "unprognostic (9.51e-3)" "unprognostic (2.70e-1)" "unprognostic (2.82e-2)" "unprognostic (2.30e-3)" "unprognostic (1.96e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (4.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.86e-1)" "unprognostic (5.52e-2)" 20.7 21.8 4.4 17.1 4.0 13.9 16.8 3.7 4.2 10.7 19.5 14.7 22.0 11.1 6.8 10.4 13.5 23.9 14.0 4.8 3.9 15.1 34.7 22.9 14.9 4.7 4.8 17.8 21.9 19.6 6.5 13.6 4.4 12.2 21.7 1.1 13.2 10.7 10.6 6.9 25.0 16.2 4.8 17.4 14.1 5.1 5.9 8.3 16.8 4.8 16.7 31.1 9.5 4.7 39.0 98.4 144.6 46.5 71.7 93.7 143.0 91.2 123.5 50.7 77.6 40.9 39.1 23.1 59.1 52.4 88.4 37.2 39.3 179.7 90.4 22.9 31.2 0.0 43.6 85.4 238.0 9.6 37.5 136.1 164.6 110.5 121.1 131.9 160.4 27.5 16.1 0.2 104.5 12.3 0.8 14.3 37.0 52.6 34.6 21.0 53.5 14.8 100.2 62.7 0.2 24.2 46.4 14.0 51.1 101.6 23.1 9.9 145.3 71.8 36.4 23.2 66.6 27.4 4.7 10.8 74.6 17.8 106.6 3.8 17.8 0.6 1.9 12.6 3.0 4.0 2.4 2.0 15.8 1.9 4.7 1.9 3.6 1.2 17.5 0.0 1.6 7.8 4.4 4.0 3.7 4.2 4.8 3.9 4.7 4.8 4.4 4.8 5.9 4.7 41.8 12.8 35.6 8.1 17.6 31.6 35.0 55.9 34.7 0.8 31.7 26.7 3.7 12.8 36.4 12.9 0.0 4.2 10.4 28.4 3.9 29.1 1.3 42.2 16.8 39.4 0.0 4.0 3.3 26.5 8.8 18.8 60.6 81.9 9.5 17.1 18.9 27.1 9.8 0.0 1.1 20.8 14.2 21.3 69.6 2.3 7.2 33.1 19.6 38.4 15.5 2.6 1.0 15.1 0.6 50.7 22.6 6.8 5.1 37.7 36.4 9.2 18.7 0.3 0.0 15.4 14.3 0.3 2.1 25.3 18.2 4.2 14.3 21.0 26.0 53.1 TNFSF18 "AITRL, hGITRL, TL6" ENSG00000120337 "TNF superfamily member 18" Q9UNG2 1 173039960-173050963 "Predicted intracellular proteins" "Adaptive immunity, Immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "gallbladder: 1.8" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 13.6;Hofbauer cells: 6.4;Squamous epithelial cells: 6.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "EFO-21: 51.4;HUVEC TERT2: 78.8;TIME: 110.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (2.78e-1)" "unprognostic (7.40e-2)" "unprognostic (3.08e-3)" "unprognostic (1.32e-2)" "unprognostic (3.39e-2)" "unprognostic (5.72e-2)" "unprognostic (2.16e-3)" "unprognostic (7.03e-2)" "unprognostic (2.22e-2)" "unprognostic (3.53e-2)" "unprognostic (1.13e-1)" "unprognostic (6.34e-2)" "unprognostic (2.71e-4)" "unprognostic (8.42e-3)" "unprognostic (6.21e-2)" "unprognostic (1.99e-1)" "unprognostic (8.74e-2)" 0.1 0.2 0.2 0.2 0.3 0.0 0.2 0.4 0.8 0.2 0.0 0.2 0.5 0.0 0.0 0.8 0.0 1.8 0.0 0.4 0.2 0.3 0.8 0.2 0.2 0.4 0.3 0.0 0.2 0.5 0.1 0.4 0.4 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.2 0.3 0.2 0.1 0.3 0.7 0.3 0.0 0.1 0.3 0.0 0.4 0.2 0.0 0.0 0.2 0.1 0.3 0.0 1.1 2.5 0.5 0.0 0.0 0.0 0.0 51.4 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 6.8 0.0 78.8 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 110.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.4 0.8 0.4 0.2 0.4 0.3 0.4 0.2 0.3 0.4 0.1 0.0 0.0 0.7 0.0 0.6 0.5 0.3 13.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.6 0.0 0.0 0.0 2.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.1 0.0 0.0 0.0 0.0 0.1 TNFSF4 "CD252, gp34, OX-40L, TXGP1" ENSG00000117586 "TNF superfamily member 4" P23510 1 173183731-173207331 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins" Cytokine "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Granulosa cells: 37.0;Macrophages: 26.4;monocytes: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 42.0;HHSteC: 17.3;HUVEC TERT2: 81.2;LHCN-M2: 67.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059579 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" "HPA059579: AB_2684071" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (4.58e-2)" "unprognostic (2.74e-1)" "unprognostic (1.73e-2)" "unprognostic (1.74e-1)" "unprognostic (1.13e-3)" "unprognostic (2.13e-1)" "unprognostic (8.65e-2)" "unprognostic (5.17e-2)" "unprognostic (1.26e-2)" "unprognostic (1.18e-1)" "unprognostic (1.11e-7)" "unprognostic (3.73e-3)" "unprognostic (2.66e-1)" "unprognostic (9.49e-2)" "unprognostic (2.98e-2)" 1.2 2.0 1.1 2.3 1.2 0.6 0.6 1.8 1.5 1.0 0.1 1.0 0.3 0.8 0.5 0.6 0.9 1.1 1.0 1.1 0.9 0.8 0.9 1.2 2.2 1.2 1.2 1.1 1.1 0.5 1.5 0.5 1.2 1.4 1.2 1.4 0.4 0.6 0.2 0.3 0.8 0.8 0.8 1.7 0.7 4.0 1.1 3.7 0.4 0.2 1.9 1.5 0.8 1.2 0.1 0.0 0.4 1.2 2.7 14.1 0.2 4.1 0.9 0.2 0.3 0.2 0.1 0.2 0.7 42.0 0.2 0.1 0.1 0.1 0.3 0.7 0.1 0.1 0.4 1.6 17.3 0.3 0.2 6.2 0.3 2.1 0.3 1.3 81.2 1.5 0.1 0.5 67.5 0.0 0.7 0.4 0.3 0.1 0.6 2.0 0.1 0.6 0.6 0.1 0.1 0.6 0.3 0.2 0.9 1.3 0.0 0.7 0.6 0.1 0.1 0.4 0.2 0.9 1.4 0.3 0.2 7.7 4.4 0.0 0.1 0.1 0.5 0.0 0.3 0.5 0.2 0.4 0.3 0.5 0.4 0.4 0.7 1.7 0.0 1.2 0.4 2.8 1.1 1.2 1.8 1.5 1.1 0.9 1.2 1.2 1.2 0.8 1.1 1.2 0.2 0.0 0.5 8.5 0.8 0.8 0.3 0.4 0.6 0.4 0.2 0.0 1.5 1.5 0.1 1.8 0.0 0.2 2.2 0.9 0.0 0.1 5.8 0.2 0.4 1.0 0.0 0.8 3.6 0.0 0.2 3.7 0.0 0.1 0.0 37.0 0.0 1.2 0.5 0.0 5.2 0.0 0.0 0.6 2.3 2.2 0.3 26.4 1.8 0.0 8.2 1.3 2.1 2.5 4.0 0.3 0.1 1.9 0.4 0.4 0.0 0.2 0.8 0.5 0.0 0.6 3.7 0.3 0.2 0.0 0.6 0.0 2.4 0.7 0.1 0.1 TNPO1 "IPO2, KPNB2, MIP, MIP1, TRN" ENSG00000083312 "Transportin 1" Q92973 5 72816312-72916733 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016325 Approved Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA 130000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Cytosol, Cytoplasmic bodies" "CAB016325: AB_675691" "unprognostic (1.16e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-3)" "unprognostic (1.43e-1)" "unprognostic (3.15e-1)" "unprognostic (6.43e-3)" "prognostic unfavorable (6.55e-5)" "unprognostic (8.93e-3)" "unprognostic (9.03e-2)" "unprognostic (3.40e-3)" "unprognostic (2.09e-1)" "unprognostic (3.07e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "unprognostic (1.27e-2)" "unprognostic (2.49e-2)" 23.5 23.0 10.6 28.8 14.6 31.7 25.0 14.0 10.0 20.2 23.0 24.5 20.5 24.0 33.8 23.1 20.6 27.7 20.8 10.5 17.1 30.5 28.4 17.3 29.9 18.2 13.4 22.4 31.5 39.8 15.6 36.8 16.5 23.4 29.9 65.0 20.9 28.1 25.0 11.6 20.9 28.2 15.1 20.6 30.7 37.3 13.1 35.6 36.8 27.0 32.3 33.3 14.0 21.5 94.8 123.7 154.5 104.8 133.3 144.5 110.4 112.3 145.6 112.2 113.6 111.4 87.1 117.5 78.5 173.0 140.4 71.6 126.3 108.8 160.8 66.6 71.9 76.2 144.8 55.9 103.9 78.4 55.1 110.8 80.2 151.0 184.8 78.2 248.6 52.9 113.4 54.8 298.1 50.3 87.2 37.3 99.3 39.8 90.9 83.1 150.5 74.1 73.4 109.5 87.5 73.6 160.6 60.3 135.8 99.8 71.2 61.9 225.1 79.5 113.8 116.8 136.7 53.2 95.8 155.8 69.9 91.3 154.4 8.2 8.2 6.9 11.9 11.0 16.5 10.3 10.9 9.3 10.3 10.8 11.6 11.9 8.4 14.1 14.0 5.0 8.3 10.5 10.6 14.6 14.0 10.0 10.5 17.1 18.2 13.4 16.5 15.1 13.1 21.5 42.3 12.8 25.0 45.7 49.0 59.1 40.9 29.7 60.3 105.0 38.7 24.0 53.8 30.0 28.7 27.6 98.0 81.9 44.9 39.8 17.6 39.0 105.4 38.6 46.1 64.8 53.2 27.1 142.2 41.5 50.0 52.8 53.0 46.7 22.1 62.8 50.7 38.1 42.7 89.2 77.8 46.3 28.5 40.0 42.2 60.9 46.6 42.1 24.9 50.6 47.4 143.1 26.8 79.9 84.7 58.9 24.9 60.2 42.9 57.0 33.9 36.1 27.6 187.9 26.3 72.5 48.8 58.5 76.3 42.0 53.3 131.3 36.9 40.2 37.2 60.2 TNRC6A "CAGH26, GW182, KIAA1460, TNRC6" ENSG00000090905 "Trinucleotide repeat containing adaptor 6A" Q8NDV7 16 24610209-24827632 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" RNA-binding Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 289.3;Excitatory neurons: 283.8;Inhibitory neurons: 414.6;Oligodendrocyte precursor cells: 265.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015305, HPA017869" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA015305: AB_1850454, HPA017869: AB_1850456" "unprognostic (2.64e-1)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.86e-1)" "unprognostic (5.00e-2)" "unprognostic (1.10e-3)" "unprognostic (1.62e-1)" "unprognostic (3.22e-3)" "unprognostic (5.49e-2)" "unprognostic (2.74e-1)" "unprognostic (7.44e-3)" "unprognostic (2.63e-3)" "unprognostic (1.78e-1)" "unprognostic (9.18e-2)" "unprognostic (5.77e-2)" "unprognostic (2.31e-1)" "unprognostic (3.35e-2)" 17.2 21.0 5.0 6.4 3.6 6.0 14.9 10.8 7.1 17.8 6.1 17.8 5.5 23.5 11.5 11.3 17.7 6.4 11.1 3.4 6.6 10.3 13.0 12.8 7.1 6.1 4.8 20.6 19.2 13.2 22.8 6.6 6.1 14.6 6.4 7.0 14.9 8.0 14.0 13.1 15.3 8.1 2.2 9.9 15.2 6.6 7.0 8.6 17.8 6.9 7.4 13.0 13.4 7.4 10.1 13.8 16.0 8.7 13.6 17.7 9.1 16.9 13.6 12.0 13.1 10.2 8.2 10.2 7.1 17.0 12.4 11.2 20.1 14.2 18.0 10.4 10.4 10.2 16.7 14.1 11.7 10.5 6.9 18.0 7.3 15.8 10.2 14.8 16.7 6.6 15.7 6.2 15.8 11.9 8.8 6.9 23.1 4.9 6.8 17.1 12.4 9.1 9.1 9.3 7.7 10.8 11.8 7.2 6.6 12.1 8.4 6.8 15.5 15.3 10.5 7.6 12.0 13.7 11.6 16.5 14.3 6.4 11.3 0.5 0.5 0.4 0.5 0.3 0.4 1.1 0.5 0.5 0.2 1.0 0.7 0.5 0.3 0.6 0.3 1.0 0.5 0.3 5.0 3.6 10.8 7.1 3.4 6.6 6.1 4.8 6.1 2.2 7.0 7.4 51.2 38.5 60.0 289.3 45.5 34.9 17.8 21.9 39.9 97.1 42.8 41.0 75.3 51.5 32.3 46.0 118.9 22.4 49.9 38.3 17.6 23.6 17.2 38.7 65.5 45.5 55.9 34.9 283.8 24.5 15.1 50.5 33.6 42.8 39.3 76.5 60.3 115.3 21.2 176.7 414.6 36.3 22.4 56.2 26.5 11.3 69.0 28.7 30.2 138.7 36.1 42.0 50.4 265.4 234.2 28.5 36.1 81.3 44.7 26.0 42.8 19.2 29.8 81.7 19.7 52.8 60.9 41.2 30.6 38.1 28.7 8.2 39.0 36.5 35.8 17.4 TRIM22 "GPSTAF50, RNF94, STAF50" ENSG00000132274 "Tripartite motif containing 22" Q8IYM9 11 5689697-5737089 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 135.9;dendritic cells: 113.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 174.6;BJ hTERT+ SV40 Large T+ RasG12V: 209.9;HSkMC: 190.6;TIME: 153.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003307, HPA003575" Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA003307: AB_1080381, HPA003575: AB_1080378" "unprognostic (1.47e-2)" "unprognostic (5.27e-3)" "unprognostic (4.00e-2)" "unprognostic (4.21e-3)" "unprognostic (2.21e-1)" "unprognostic (1.21e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (1.86e-3)" "unprognostic (2.93e-2)" "unprognostic (2.10e-1)" "unprognostic (1.98e-2)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" "unprognostic (1.15e-1)" "unprognostic (9.16e-2)" 54.0 21.3 13.1 101.3 18.8 90.3 50.7 16.3 23.7 42.7 25.5 36.0 25.2 50.6 70.2 37.1 49.3 78.6 22.6 14.7 16.5 21.2 72.5 83.4 139.0 17.9 16.7 60.3 17.2 8.0 12.6 21.5 16.7 43.3 53.4 11.0 65.4 52.6 13.4 18.1 53.4 52.1 17.7 143.1 39.5 15.4 12.8 101.2 21.7 40.6 120.7 61.6 22.6 29.3 2.8 1.2 13.9 2.4 88.6 174.6 5.0 53.3 93.9 89.8 209.9 1.7 8.6 111.9 13.0 80.2 20.6 10.5 34.0 56.4 10.7 2.0 0.0 6.4 5.6 1.4 107.8 18.2 11.4 190.6 54.3 18.7 9.6 124.5 128.7 1.0 2.3 4.7 111.6 1.5 54.1 16.9 40.3 0.5 4.9 62.6 3.4 2.3 51.1 14.9 1.4 2.7 4.5 4.5 2.1 56.8 4.5 17.9 153.6 56.4 29.8 2.5 2.4 4.9 4.4 11.2 67.7 28.9 7.2 108.7 118.5 79.6 109.0 143.3 145.9 149.4 118.4 117.2 138.7 158.2 106.5 102.7 103.1 61.3 181.1 177.0 197.9 181.9 13.1 18.8 16.3 23.7 14.7 16.5 17.9 16.7 16.7 17.7 12.8 29.3 54.4 67.3 57.7 2.0 135.9 12.6 17.0 42.5 56.3 0.5 17.7 14.0 6.0 7.2 60.5 29.5 0.0 1.5 113.9 4.7 5.9 11.2 0.3 16.1 27.0 40.5 4.2 16.8 4.9 8.0 4.7 36.2 20.9 23.8 17.7 5.4 33.5 4.3 18.7 1.7 0.3 9.0 30.5 87.1 46.6 2.0 36.1 67.8 5.4 52.5 59.0 6.4 83.4 1.0 0.5 5.4 6.3 30.1 18.8 9.9 4.4 3.3 52.5 1.0 13.1 35.1 24.4 0.6 0.3 14.1 8.7 2.3 89.3 13.0 5.0 18.8 TRIM5 "RNF88, TRIM5alpha" ENSG00000132256 "Tripartite motif containing 5" Q9C035 11 5663195-5938619 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Antiviral defense, Autophagy, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB013497, HPA023420, HPA023422" Approved Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB013497: , HPA023420: AB_1856378, HPA023422: AB_1856379" "unprognostic (2.60e-1)" "unprognostic (9.62e-2)" "unprognostic (2.04e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (4.74e-3)" "unprognostic (5.48e-3)" "unprognostic (5.82e-2)" "unprognostic (1.49e-1)" "unprognostic (6.76e-3)" "unprognostic (8.54e-3)" "unprognostic (1.64e-1)" "unprognostic (2.20e-2)" "unprognostic (1.90e-1)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (6.12e-2)" 8.8 10.9 2.1 8.1 2.3 3.8 8.0 2.0 2.4 11.8 7.2 7.2 7.4 11.7 18.4 7.7 9.4 6.9 5.7 2.0 3.3 9.0 12.8 11.8 8.4 4.0 3.5 11.4 13.3 4.2 3.8 9.6 3.4 8.5 7.7 1.9 14.0 9.1 1.9 5.5 8.5 11.3 3.0 10.4 7.8 8.3 3.5 9.4 9.6 4.0 8.9 8.2 8.6 2.9 7.7 15.4 19.2 12.4 24.0 22.5 5.4 18.0 35.0 37.3 50.0 13.8 13.5 5.5 13.3 18.8 27.6 13.0 18.4 25.8 14.9 9.6 5.1 15.2 10.4 9.5 20.2 11.5 15.3 15.4 22.7 10.5 31.3 22.9 52.8 8.9 16.9 12.2 32.1 4.2 7.7 5.3 7.7 11.7 8.1 14.3 4.7 1.5 23.7 14.4 0.5 1.1 11.8 18.4 6.8 20.7 9.3 6.6 43.3 13.9 20.2 3.6 4.2 9.4 7.9 1.9 10.9 6.8 15.4 10.7 7.6 11.6 3.6 7.8 3.0 3.1 2.8 2.8 9.4 2.6 1.8 3.7 7.7 4.1 8.0 7.0 2.2 4.1 2.1 2.3 2.0 2.4 2.0 3.3 4.0 3.5 3.4 3.0 3.5 2.9 14.2 6.4 14.0 4.9 8.7 5.2 9.5 9.7 9.6 0.2 8.3 6.5 4.9 2.8 13.4 11.0 0.0 7.8 16.4 5.5 5.9 10.6 5.0 8.6 12.6 14.8 1.2 8.4 3.0 8.8 10.5 12.4 6.1 12.5 0.0 11.9 15.4 13.9 6.4 0.0 1.4 9.7 4.1 12.2 7.1 3.8 7.8 10.8 3.6 19.7 10.8 7.0 14.4 3.0 1.0 8.1 4.9 7.5 6.7 10.1 7.4 6.3 3.7 0.1 19.7 6.5 10.9 5.2 3.3 7.0 5.4 7.8 7.5 20.6 7.5 9.9 TRIP10 "CIP4, HSTP, STOT, STP" ENSG00000125733 "Thyroid hormone receptor interactor 10" Q15642 19 6737925-6751530 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 362.8" "Cell type enhanced" "Detected in many" "monocytes: 196.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 26.4" "Lineage enriched" "Detected in many" 10 "dendritic cells: 26.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041934, HPA072625, HPA073886" Approved Supported Nucleoplasm,Vesicles NA NA 24000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 3: Monocytes - Immune response regulation" Vesicles Nucleoplasm "HPA041934: AB_2677754, HPA072625: AB_2732206, HPA073886: AB_2732244" "unprognostic (5.75e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.19e-2)" "unprognostic (6.57e-2)" "prognostic favorable (1.76e-4)" "unprognostic (6.73e-3)" "unprognostic (1.10e-3)" "unprognostic (1.51e-1)" "unprognostic (3.41e-1)" "unprognostic (7.87e-3)" "unprognostic (3.28e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.14e-2)" "unprognostic (1.42e-1)" "unprognostic (8.93e-2)" "unprognostic (8.83e-2)" 110.7 60.3 15.5 25.5 15.6 8.6 92.3 15.3 17.8 123.9 18.6 112.1 30.5 66.5 17.5 253.3 80.1 27.6 125.7 14.6 16.7 81.7 27.0 115.4 14.5 17.5 16.5 99.4 44.7 18.6 22.4 48.6 16.0 80.4 19.9 16.9 85.4 45.0 362.8 57.8 56.0 26.4 15.8 40.0 58.6 29.9 17.5 9.6 75.5 177.3 21.9 86.7 147.4 14.8 83.5 49.7 17.1 25.8 64.7 67.9 61.1 52.5 60.0 58.8 51.1 67.8 46.7 1.8 69.2 44.6 47.6 60.2 38.8 76.5 34.7 52.5 15.5 27.0 48.4 52.3 53.4 1.4 8.3 79.0 50.9 52.5 39.8 77.2 61.2 3.7 40.2 22.1 43.7 28.3 7.5 18.7 36.3 51.9 41.7 12.2 35.1 24.5 50.0 40.9 0.1 19.6 69.1 30.7 20.0 39.4 32.2 14.7 120.5 39.3 70.4 103.8 56.4 23.1 13.4 8.4 63.6 7.9 26.2 0.0 0.8 0.0 0.6 0.1 0.9 1.5 0.3 1.1 5.2 1.7 0.3 0.2 0.1 2.5 0.1 26.4 0.0 0.5 15.5 15.6 15.3 17.8 14.6 16.7 17.5 16.5 16.0 15.8 17.5 14.8 43.0 28.9 19.8 6.5 5.6 85.4 104.9 76.9 43.9 14.7 28.3 16.6 8.7 20.0 66.9 16.5 37.5 9.9 16.5 39.1 5.9 45.0 16.4 30.3 32.1 43.1 7.7 4.4 0.1 38.0 37.9 66.3 10.7 55.7 29.7 8.8 38.9 3.7 9.6 0.0 0.2 16.3 24.4 6.7 90.4 13.6 55.9 19.6 37.4 3.7 196.9 12.5 0.0 5.5 0.4 91.5 24.7 36.1 9.0 116.6 25.8 23.8 24.8 18.5 32.9 26.4 46.4 5.7 6.9 51.3 83.3 14.2 7.4 24.5 25.9 120.7 TRPV4 "CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC" ENSG00000111199 "Transient receptor potential cation channel subfamily V member 4" Q9HBA0 12 109783087-109833406 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Charcot-Marie-Tooth disease, Disease variant, Dwarfism, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 50.8;salivary gland: 19.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 17.1;Cholangiocytes: 20.0;Cytotrophoblasts: 20.0;Kupffer cells: 19.6;Respiratory ciliated cells: 28.2;Syncytiotrophoblasts: 21.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 5 "hippocampal formation: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 7.9;BJ hTERT+: 9.5;EFO-21: 7.2;HaCaT: 14.2;HUVEC TERT2: 8.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007150 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA007150: AB_1080393" "unprognostic (2.98e-2)" "unprognostic (1.12e-2)" "unprognostic (2.33e-2)" "unprognostic (4.20e-3)" "unprognostic (6.25e-3)" "unprognostic (1.09e-2)" "unprognostic (7.95e-2)" "unprognostic (2.03e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "prognostic favorable (4.12e-5)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" 1.0 0.8 0.2 0.9 0.3 0.1 1.9 0.7 0.5 2.0 50.8 0.4 0.7 0.6 0.4 10.3 4.7 1.4 0.8 4.2 0.2 14.7 8.6 2.2 0.8 0.5 0.4 0.3 4.4 0.3 2.1 5.2 0.3 6.8 0.3 0.0 19.2 0.8 0.1 7.5 0.4 0.7 0.2 2.8 0.7 0.8 0.8 0.1 0.9 0.0 0.9 1.8 2.2 0.4 2.4 0.2 0.0 0.0 2.0 1.2 7.9 4.2 9.5 1.2 0.3 0.0 6.4 0.0 7.2 5.8 0.0 14.2 1.0 0.0 0.4 0.0 1.8 0.0 0.1 3.7 0.6 0.0 0.0 3.4 2.0 2.7 0.0 0.6 8.7 0.0 0.5 0.0 0.4 5.3 0.0 0.0 1.5 0.0 0.0 0.0 0.5 0.0 0.0 4.9 0.0 0.0 0.3 0.6 2.6 3.5 1.1 0.2 4.5 0.0 2.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.5 4.2 0.2 0.5 0.4 0.3 0.2 0.8 0.4 0.1 0.0 0.0 0.0 0.7 3.3 8.1 17.1 7.4 0.0 5.1 5.5 1.0 20.0 12.0 11.0 0.0 20.0 0.4 0.0 3.9 2.5 0.2 3.2 1.0 1.4 0.0 0.0 0.3 9.3 5.3 1.2 2.0 1.2 0.0 0.9 0.7 7.7 4.0 0.0 0.4 0.0 6.1 19.6 0.7 0.2 0.9 2.6 7.2 1.9 0.8 0.0 0.0 1.0 0.3 2.0 0.0 0.0 0.0 4.6 0.0 12.5 28.2 0.0 0.0 0.1 1.1 0.3 1.1 4.5 3.8 21.1 0.3 0.2 0.0 3.3 TSPAN14 "DC-TM4F2, MGC11352, TM4SF14" ENSG00000108219 "Tetraspanin 14" Q8NG11 10 80454166-80533124 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 156.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 276.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014773, HPA057174" Uncertain Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA014773: AB_2208670, HPA057174: " "unprognostic (7.52e-2)" "prognostic favorable (3.56e-4)" "unprognostic (6.55e-3)" "unprognostic (1.56e-1)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (2.11e-2)" "unprognostic (8.90e-2)" "unprognostic (5.21e-2)" "unprognostic (3.13e-1)" "unprognostic (5.15e-3)" "unprognostic (4.12e-3)" "prognostic favorable (4.20e-4)" "unprognostic (2.52e-2)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (2.57e-3)" 97.9 20.7 29.1 43.1 24.2 57.2 80.1 25.1 29.7 63.1 19.4 33.4 30.9 38.4 44.1 92.1 47.1 32.9 51.2 26.2 21.4 45.7 21.1 70.8 54.2 31.7 32.2 47.2 33.1 35.7 15.7 81.9 29.7 34.8 27.1 7.9 47.7 34.1 24.9 74.3 34.8 33.3 31.2 48.5 24.7 23.2 32.8 40.1 46.5 42.1 44.6 55.0 56.1 31.4 96.2 135.6 128.3 44.5 186.6 59.3 59.6 49.3 91.8 51.1 38.0 134.8 54.6 31.5 93.2 26.4 18.9 97.0 35.9 88.5 41.4 55.9 13.9 88.9 15.8 118.2 63.5 31.8 20.3 58.8 77.2 52.8 92.1 94.8 191.5 31.8 48.8 23.0 15.0 83.3 50.0 23.3 29.5 61.2 0.1 167.9 14.9 5.3 203.9 131.9 27.5 42.3 19.7 133.7 149.5 43.7 54.1 79.8 276.3 13.0 52.8 12.4 35.1 10.7 42.0 11.8 42.2 65.4 57.5 16.2 51.5 56.3 92.1 102.1 41.3 13.8 70.7 81.1 33.9 13.7 82.3 79.3 54.7 95.2 172.8 13.6 61.8 84.3 29.1 24.2 25.1 29.7 26.2 21.4 31.7 32.2 29.7 31.2 32.8 31.4 141.9 16.0 55.1 13.1 18.5 34.9 40.3 54.6 35.3 2.1 29.5 23.2 11.3 25.8 39.0 33.1 77.2 7.8 38.4 32.8 7.9 43.8 2.4 44.7 38.9 95.3 64.2 35.6 12.9 24.8 74.4 18.8 18.3 75.1 7.6 41.2 156.7 21.1 50.5 3.3 7.4 37.0 34.6 129.3 12.9 4.1 39.1 66.5 14.2 35.6 51.8 23.7 89.6 4.5 13.5 64.2 21.6 41.0 18.4 55.7 23.4 8.0 29.6 7.1 98.6 10.2 43.1 5.0 19.0 80.2 36.4 7.7 55.7 10.4 30.6 69.7 TTC37 "KIAA0372, THES" ENSG00000198677 "Tetratricopeptide repeat domain 37" Q6PGP7 5 95461755-95554977 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037905 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA037905: AB_10673034" "unprognostic (5.99e-2)" "unprognostic (7.65e-3)" "prognostic favorable (2.62e-4)" "unprognostic (8.48e-2)" "unprognostic (9.49e-2)" "unprognostic (5.39e-2)" "unprognostic (1.40e-2)" "unprognostic (2.18e-1)" "unprognostic (6.88e-2)" "unprognostic (5.97e-2)" "unprognostic (6.81e-3)" "unprognostic (2.51e-1)" "unprognostic (3.30e-3)" "unprognostic (6.88e-3)" "unprognostic (3.91e-1)" "unprognostic (3.98e-2)" "unprognostic (7.90e-3)" 23.6 24.2 10.6 17.9 13.1 10.5 25.7 21.4 15.4 23.8 14.8 20.2 21.4 22.8 19.7 19.9 16.9 18.4 24.3 12.3 11.7 27.5 23.2 17.1 20.5 15.0 12.2 22.6 26.7 46.1 20.2 25.9 15.9 27.2 22.1 21.8 20.7 21.4 34.5 32.7 19.2 22.2 12.7 19.4 26.2 7.8 13.3 25.8 26.2 30.9 21.5 17.0 16.7 18.5 33.1 34.6 43.0 14.9 70.3 94.9 38.2 61.8 49.6 39.3 58.6 37.1 23.6 58.0 39.7 59.0 41.0 31.7 54.5 74.5 65.4 34.0 44.6 39.1 68.8 24.6 60.1 25.7 27.1 63.6 37.3 50.1 69.5 60.3 63.0 19.0 31.2 37.1 75.1 19.0 33.5 20.6 24.3 15.1 28.2 28.1 60.0 61.5 43.2 25.7 53.5 41.8 50.8 24.8 57.0 35.7 38.8 21.7 87.4 53.3 30.5 42.5 47.9 35.4 48.3 53.0 54.0 36.9 70.0 6.1 6.4 2.4 10.1 7.8 12.2 10.3 9.8 8.5 8.1 10.0 10.0 10.6 0.2 9.3 8.0 16.2 9.7 4.4 10.6 13.1 21.4 15.4 12.3 11.7 15.0 12.2 15.9 12.7 13.3 18.5 51.4 76.9 56.1 68.6 38.5 19.5 20.4 26.5 8.6 57.8 33.2 31.8 84.9 25.8 40.9 27.6 50.1 32.5 52.0 22.4 15.6 41.5 2.4 44.8 70.9 39.9 32.5 20.2 146.8 40.5 41.8 43.4 42.8 57.3 41.1 64.6 32.9 36.0 26.9 58.9 130.6 34.3 16.2 28.8 16.7 4.3 62.4 32.2 8.8 68.4 55.4 21.0 41.2 99.5 145.0 38.1 20.2 64.7 41.1 19.0 32.2 30.7 38.2 33.6 39.5 55.1 39.5 10.5 10.0 30.9 32.8 19.8 34.8 52.3 34.2 18.2 TTLL5 KIAA0998 ENSG00000119685 "Tubulin tyrosine ligase like 5" Q6EMB2 14 75633625-75955079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transcription Ligase "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 57.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 127.2;Early spermatids: 111.0;Excitatory neurons: 134.3;Inhibitory neurons: 114.2;Oligodendrocytes: 242.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032128 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA032128: AB_10600835" "unprognostic (7.35e-2)" "unprognostic (7.29e-2)" "unprognostic (7.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (5.96e-2)" "unprognostic (7.21e-5)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (7.93e-2)" "unprognostic (1.10e-2)" "unprognostic (3.43e-1)" "unprognostic (5.67e-3)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (8.97e-2)" "unprognostic (2.15e-2)" 5.5 5.5 3.7 6.0 6.0 11.7 7.1 7.1 7.2 7.3 15.0 6.2 4.7 8.0 7.2 7.8 11.6 6.5 5.8 3.8 6.6 6.2 4.1 6.5 5.1 10.5 6.4 7.1 4.9 11.1 5.4 7.5 10.6 6.9 7.3 23.9 6.5 6.9 4.7 7.1 4.5 8.6 6.4 4.1 5.9 57.4 6.4 10.1 7.8 5.8 7.5 6.1 6.4 12.0 22.8 16.2 13.9 14.5 10.9 16.8 12.9 13.1 15.9 15.4 19.9 10.3 20.8 6.4 7.2 13.9 11.3 21.3 12.3 21.7 29.3 7.6 7.3 12.5 16.8 11.3 9.3 9.2 11.5 13.1 10.6 19.4 21.5 16.8 33.8 17.5 7.2 10.5 15.7 32.1 15.6 12.6 9.9 18.0 16.6 9.5 19.6 8.8 15.0 22.2 18.4 11.6 27.5 20.2 6.8 11.0 27.6 9.8 38.1 20.5 18.0 18.5 12.2 8.8 13.5 14.6 20.7 10.4 13.9 11.6 2.0 1.7 2.6 2.0 2.4 2.3 2.5 2.7 3.2 1.8 2.9 2.7 2.4 2.3 2.5 3.4 2.2 1.4 3.7 6.0 7.1 7.2 3.8 6.6 10.5 6.4 10.6 6.4 6.4 12.0 7.1 3.2 10.1 71.8 6.1 5.0 5.5 5.4 8.0 10.9 17.3 11.6 8.7 17.2 10.2 11.0 127.2 8.1 8.5 7.6 3.9 7.1 111.0 37.4 11.9 10.7 7.7 5.0 134.3 5.3 13.2 9.3 8.6 10.8 12.6 11.7 19.6 7.4 5.6 0.0 114.2 6.5 16.2 5.8 5.1 93.1 12.5 6.6 5.4 82.4 8.5 10.0 6.2 78.4 242.9 6.1 11.9 11.7 7.6 6.2 6.0 2.4 40.1 80.1 13.1 9.5 6.0 37.7 16.4 9.0 6.3 6.0 8.3 9.1 8.0 4.6 UBTD1 FLJ11807 ENSG00000165886 "Ubiquitin domain containing 1" Q9HAC8 10 97498924-97571206 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.4;neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034825 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane, Cytosol" "HPA034825: AB_10602254" "unprognostic (1.52e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (5.54e-4)" "unprognostic (2.43e-1)" "unprognostic (1.78e-1)" "unprognostic (3.90e-2)" "unprognostic (3.63e-3)" "unprognostic (1.43e-2)" "unprognostic (1.66e-3)" "unprognostic (9.25e-3)" "unprognostic (2.45e-1)" "unprognostic (4.78e-1)" "unprognostic (6.62e-3)" "unprognostic (8.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.47e-3)" "unprognostic (3.50e-3)" 18.8 11.1 14.9 5.7 15.2 8.8 14.7 16.8 17.0 16.5 12.6 10.3 1.8 13.5 4.0 9.5 13.6 7.0 35.1 13.5 15.8 29.2 18.6 29.8 3.1 17.7 17.1 8.7 9.6 3.6 15.9 3.8 16.2 13.4 0.6 6.0 11.2 7.5 34.2 49.5 5.5 3.6 16.1 11.0 9.4 60.3 18.9 1.6 14.6 11.2 1.1 12.4 16.3 14.6 18.1 17.7 4.6 23.0 18.9 17.8 5.4 20.3 29.4 21.3 16.3 12.0 15.4 2.2 24.1 13.8 13.4 21.4 4.6 27.2 3.0 5.6 9.1 2.2 5.5 15.2 27.2 2.0 5.9 24.6 9.0 23.3 5.7 32.8 34.3 4.7 1.2 3.3 13.9 8.6 0.9 18.5 7.5 3.4 32.1 1.8 8.1 2.1 16.7 6.7 1.5 4.8 9.2 5.6 27.1 4.0 20.8 13.6 37.5 26.9 16.4 28.4 26.8 4.2 5.1 0.9 22.7 12.3 14.3 1.0 2.6 6.4 0.1 0.7 0.1 0.3 0.0 0.0 1.4 0.0 0.0 0.0 6.6 0.0 0.7 0.9 0.3 0.5 14.9 15.2 16.8 17.0 13.5 15.8 17.7 17.1 16.2 16.1 18.9 14.6 5.0 41.7 28.6 13.1 1.1 26.0 8.8 32.2 19.4 3.8 10.0 4.8 15.5 8.6 21.2 7.3 4.2 3.5 0.6 1.5 11.7 18.9 53.5 8.2 8.7 23.8 0.0 0.4 5.6 12.8 12.8 11.6 2.6 4.0 0.0 0.8 7.9 7.0 25.8 6.7 5.9 0.2 10.2 10.1 18.9 33.8 12.8 10.3 10.6 12.2 8.4 16.5 2.1 2.0 14.5 22.1 0.1 9.4 3.0 14.0 0.0 10.4 19.1 18.6 13.1 8.5 10.3 7.5 7.9 8.2 29.7 2.9 1.9 1.5 0.4 7.6 UGP2 "SVUGP2, UGP1, UGPP1" ENSG00000169764 "UDP-glucose pyrophosphorylase 2" Q16851 2 63840952-63891562 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 858.6;tongue: 756.1" "Cell type enhanced" "Detected in all" "Distal enterocytes: 849.9;Hepatocytes: 559.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 417.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034696, HPA034697, HPA064836" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria NA NA 13000000 "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Centrosome, Mitochondria" Nucleoplasm "HPA034696: AB_10670171, HPA034697: AB_2674287, HPA064836: AB_2685365" "unprognostic (1.00e-2)" "unprognostic (6.93e-2)" "unprognostic (5.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.65e-2)" "unprognostic (1.91e-1)" "prognostic favorable (2.50e-5)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.57e-2)" "unprognostic (8.31e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-2)" "unprognostic (3.93e-2)" "unprognostic (3.81e-1)" "unprognostic (8.44e-2)" 267.3 72.0 79.8 65.8 89.3 40.1 119.7 72.7 109.8 65.9 78.8 177.9 66.0 75.2 50.6 97.5 68.9 60.7 232.5 87.9 81.4 105.4 858.6 65.4 65.7 77.7 77.0 47.0 74.4 113.3 49.8 137.8 77.6 57.4 159.3 36.8 92.9 66.2 498.0 59.1 67.6 78.5 73.2 50.8 69.5 38.3 83.3 106.2 64.5 756.1 73.7 88.4 63.7 91.8 122.3 77.6 63.1 42.0 176.1 222.4 220.6 129.1 116.1 82.7 89.4 170.0 104.5 149.5 48.3 165.6 79.9 57.4 73.4 102.6 137.0 99.2 35.7 86.5 50.4 117.9 87.0 79.1 73.9 148.1 175.8 76.1 80.3 108.4 119.4 38.9 48.2 58.1 327.8 56.7 104.6 75.2 122.9 207.7 50.1 80.4 117.9 84.5 147.4 77.7 36.5 29.6 103.3 149.8 64.3 162.6 51.7 59.2 144.3 84.4 125.9 113.8 90.5 101.3 51.4 174.9 99.2 122.7 225.7 417.1 33.0 53.1 48.0 40.7 51.8 33.0 53.6 50.1 27.9 31.8 57.6 53.6 45.4 70.0 39.5 29.7 127.2 62.0 79.8 89.3 72.7 109.8 87.9 81.4 77.7 77.0 77.6 73.2 83.3 91.8 73.4 28.9 54.0 107.4 65.3 75.8 87.8 245.9 34.7 49.6 360.6 87.1 264.3 104.4 171.6 47.8 64.6 414.3 81.1 849.9 242.6 140.6 91.5 53.0 106.3 69.8 44.5 56.0 86.1 103.6 445.5 159.3 79.0 49.5 67.8 42.4 63.5 559.4 120.9 87.5 78.4 179.8 144.5 102.4 90.2 86.1 79.2 89.1 96.0 62.8 139.7 58.8 154.5 37.2 79.3 91.6 313.9 77.5 60.7 81.2 176.2 284.4 139.3 57.3 72.3 50.5 129.2 84.9 54.9 50.9 57.8 472.8 143.1 90.6 189.5 109.1 UHRF2 "MGC33463, NIRF, RNF107, TDRD23, URF2" ENSG00000147854 "Ubiquitin like with PHD and ring finger domains 2" Q96PU4 9 6413151-6507054 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 78.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026633, HPA026697" Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA026633: AB_2732431, HPA026697: AB_2732432" "unprognostic (1.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (8.40e-2)" "unprognostic (4.35e-3)" "unprognostic (4.12e-2)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "unprognostic (5.69e-3)" "unprognostic (2.14e-2)" "unprognostic (6.21e-2)" "unprognostic (8.77e-2)" "unprognostic (7.42e-2)" "unprognostic (1.50e-1)" 10.0 8.1 8.2 9.9 10.3 44.6 9.7 14.9 10.4 12.9 10.4 11.6 6.2 12.9 10.0 8.3 9.9 7.9 7.2 8.7 9.2 8.1 7.9 7.8 17.3 9.4 8.6 12.4 10.7 9.7 5.4 12.1 9.4 15.3 9.2 9.2 8.5 12.6 11.0 7.7 8.5 14.0 8.8 10.4 8.3 8.4 10.0 21.2 8.1 11.9 16.6 11.4 10.1 14.3 18.1 18.8 26.7 11.9 21.4 30.7 20.5 43.9 23.4 23.7 41.2 12.4 12.0 26.9 9.2 19.2 21.8 11.9 24.6 22.5 36.0 53.6 14.9 46.3 36.2 19.7 17.8 19.3 16.1 13.5 14.1 18.4 44.5 44.4 93.2 25.4 5.1 24.0 56.0 5.9 37.0 79.2 10.8 24.8 14.8 43.1 12.4 8.7 17.2 11.3 24.8 9.4 16.6 11.0 25.6 32.1 14.0 41.9 78.6 25.2 10.0 11.0 34.4 7.2 23.2 30.4 12.4 18.2 10.2 4.0 0.5 2.7 1.2 0.5 0.8 1.8 1.8 1.0 0.3 2.9 1.0 1.2 0.5 0.6 0.9 1.2 1.9 0.6 8.2 10.3 14.9 10.4 8.7 9.2 9.4 8.6 9.4 8.8 10.0 14.3 27.5 6.4 14.4 24.2 33.9 21.5 10.2 6.2 12.0 22.0 13.8 13.1 59.0 4.3 8.4 12.9 31.3 13.2 31.3 9.1 1.9 5.2 23.6 12.8 22.9 24.1 7.1 34.9 44.2 4.0 9.9 16.0 20.9 24.5 17.7 27.8 12.8 14.6 10.7 28.6 53.3 14.8 4.1 12.6 9.3 8.1 19.3 15.6 21.4 51.5 12.5 6.4 16.5 46.8 78.6 6.2 14.4 14.7 30.1 16.0 10.2 7.3 6.3 34.8 13.1 14.4 18.8 46.2 23.4 16.1 19.0 5.9 29.0 13.7 12.6 9.8 UNC45A "GC-UNC45, SMAP-1" ENSG00000140553 "Unc-45 myosin chaperone A" Q9H3U1 15 90930180-90954093 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Myogenesis" "Chaperone, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039228 Approved Supported "Nuclear speckles,Cytosol" NA NA 17000 "Cluster 27: Non-specific - Gene expression" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear speckles" Cytosol "HPA039228: AB_2676402" "unprognostic (1.46e-1)" "unprognostic (3.83e-2)" "unprognostic (4.51e-2)" "unprognostic (1.97e-1)" "unprognostic (2.68e-2)" "unprognostic (1.70e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (2.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (1.98e-1)" "unprognostic (9.85e-2)" "prognostic favorable (7.46e-7)" "unprognostic (9.30e-2)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-2)" 25.0 25.3 7.7 16.7 8.2 17.3 23.2 8.6 9.1 32.0 10.0 41.2 16.4 38.1 11.0 31.4 28.4 17.3 15.9 7.8 7.7 18.9 13.0 20.2 18.9 8.9 11.6 26.1 22.3 33.2 17.5 19.6 9.5 25.2 13.4 5.6 25.8 34.1 9.6 37.7 23.5 28.0 8.3 19.7 28.5 13.1 9.6 18.0 19.5 10.6 17.3 39.3 29.4 8.0 38.2 76.3 30.9 27.2 83.0 38.0 27.3 42.4 36.2 56.5 45.1 61.3 49.4 44.7 55.5 53.8 32.5 82.1 52.9 54.4 26.6 49.8 75.9 86.2 77.0 44.4 46.8 21.5 56.2 47.3 65.8 55.7 40.5 54.2 77.5 35.1 38.6 35.8 43.3 62.2 28.1 18.6 41.8 69.5 38.0 54.8 46.9 48.1 38.4 89.2 43.1 39.4 57.1 55.9 54.3 36.8 50.8 44.3 77.0 48.0 34.1 40.4 45.0 33.6 50.5 21.1 46.6 49.7 49.8 11.5 8.3 5.0 11.8 7.3 11.3 7.9 9.6 9.1 10.4 6.3 7.8 7.4 1.6 9.8 11.6 9.1 9.3 9.8 7.7 8.2 8.6 9.1 7.8 7.7 8.9 11.6 9.5 8.3 9.6 8.0 21.7 22.4 22.4 9.4 23.2 16.3 24.8 26.1 30.1 27.2 17.2 19.6 12.7 35.8 23.8 18.4 18.8 53.6 17.5 26.9 13.7 33.6 26.7 12.8 20.3 25.3 37.0 25.2 19.1 18.2 22.7 23.7 26.5 22.1 29.2 30.9 18.9 13.4 28.2 18.5 18.4 15.9 26.4 12.2 14.0 29.0 29.5 20.7 19.6 9.4 28.8 21.5 27.8 7.1 11.0 23.3 26.0 51.6 20.6 16.8 22.0 19.6 11.7 35.1 32.9 15.2 33.9 24.8 6.4 33.9 18.8 46.2 21.4 26.0 22.7 20.3 USP12 USP12L1 ENSG00000152484 "Ubiquitin specific peptidase 12" O75317 13 27066156-27171811 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 153.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, HPA059492" Uncertain Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA007288: AB_1080531, HPA059492: " "unprognostic (6.72e-3)" "unprognostic (2.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (5.85e-2)" "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "unprognostic (8.38e-2)" "unprognostic (8.77e-2)" "unprognostic (2.20e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (2.91e-1)" "unprognostic (6.77e-2)" "unprognostic (1.73e-1)" 20.4 13.6 21.0 20.9 22.0 75.7 15.3 21.6 26.7 13.1 15.5 35.6 18.2 13.2 15.1 17.0 13.5 17.9 14.4 23.7 22.2 24.8 34.9 23.6 29.4 18.9 24.8 14.7 15.3 16.5 13.8 17.7 19.5 14.0 25.5 38.0 10.2 12.1 13.1 24.0 24.3 18.6 21.0 17.2 17.7 15.5 22.2 12.2 16.1 15.9 26.4 21.8 13.5 21.8 24.9 15.3 28.6 14.9 18.8 23.8 10.2 34.1 23.9 18.5 13.7 27.7 37.8 35.1 16.6 27.0 44.9 15.0 18.9 19.8 39.4 57.0 16.1 54.3 19.2 19.6 23.6 31.8 36.5 14.9 28.3 21.0 23.9 23.4 43.3 23.8 18.4 16.5 38.9 14.4 19.6 42.0 20.5 31.5 26.7 22.1 36.5 8.3 36.3 17.3 31.5 19.0 29.3 24.2 28.2 35.5 11.4 30.4 51.6 19.3 18.6 41.6 31.4 12.6 15.0 24.6 32.4 18.5 22.0 0.0 0.5 2.2 0.5 0.5 0.9 1.2 0.9 0.8 0.6 1.6 0.6 0.6 0.5 0.9 0.8 1.1 1.4 0.4 21.0 22.0 21.6 26.7 23.7 22.2 18.9 24.8 19.5 21.0 22.2 21.8 54.2 28.9 29.9 19.6 42.1 91.6 29.4 7.0 34.7 23.8 30.6 24.0 23.4 17.2 9.1 23.9 39.6 15.4 26.5 47.0 29.4 12.8 19.2 29.1 26.4 42.0 20.9 60.6 37.0 16.3 7.0 34.2 23.9 68.9 13.3 15.7 21.4 23.3 14.0 28.6 29.0 27.5 10.2 20.8 153.8 10.7 7.8 47.8 39.2 42.2 33.6 13.8 9.2 43.7 65.0 24.4 37.4 6.4 37.1 34.0 34.3 21.3 12.2 32.1 32.9 114.7 42.8 2.7 12.9 23.1 79.0 10.9 27.2 9.3 24.1 40.6 UTRN "DMDL, DRP, DRP1" ENSG00000152818 Utrophin P46939 6 144285701-144853034 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 410.3;Early spermatids: 527.1;Late spermatids: 332.1;Microglial cells: 425.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HAP1: 219.4;HUVEC TERT2: 157.0;TIME: 203.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016348, HPA018894" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 4200 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "CAB016348: AB_628424, HPA018894: AB_10600839" "unprognostic (3.47e-2)" "unprognostic (2.82e-1)" "unprognostic (2.32e-1)" "unprognostic (6.87e-3)" "unprognostic (1.75e-1)" "unprognostic (3.30e-2)" "unprognostic (3.99e-3)" "unprognostic (2.44e-1)" "unprognostic (9.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.10e-2)" "prognostic favorable (7.61e-5)" "unprognostic (6.32e-2)" "unprognostic (2.20e-1)" "unprognostic (1.66e-1)" "unprognostic (1.49e-2)" 52.6 17.4 26.8 25.8 40.5 56.6 40.5 32.7 18.3 40.4 35.6 33.8 17.0 29.8 16.8 27.9 43.5 31.2 24.8 18.4 67.9 30.9 25.3 49.3 34.9 48.6 52.1 37.2 52.1 69.4 7.9 45.8 49.7 39.7 31.7 11.0 26.0 26.1 14.0 27.5 22.3 25.9 40.0 71.5 27.2 59.2 48.8 43.2 68.4 38.9 35.8 25.2 16.0 31.0 27.2 22.6 39.3 51.0 66.5 60.5 23.4 39.0 37.8 31.1 45.2 86.1 9.8 8.4 33.6 88.4 36.6 15.6 219.4 32.9 44.6 90.6 25.5 32.2 24.9 51.6 26.3 36.1 0.7 35.5 6.8 46.2 24.1 29.3 157.0 25.1 2.0 22.7 44.1 18.1 28.7 15.5 15.9 16.6 23.9 25.7 70.2 0.8 35.9 0.7 49.7 0.9 60.8 8.4 23.5 59.5 33.3 48.2 203.6 29.8 37.0 15.5 37.6 17.7 25.3 1.3 18.2 21.5 49.5 41.2 40.9 23.2 39.5 120.8 28.3 25.7 24.9 33.0 17.2 35.7 21.8 22.8 34.5 37.6 173.9 50.4 22.2 13.9 26.8 40.5 32.7 18.3 18.4 67.9 48.6 52.1 49.7 40.0 48.8 31.0 267.0 410.3 138.7 148.2 101.2 29.4 31.7 17.2 40.9 6.5 47.4 32.1 56.0 28.6 111.0 31.3 0.0 94.4 175.1 10.9 0.0 25.3 527.1 61.2 51.5 171.8 31.2 19.8 61.2 32.0 6.9 51.6 76.5 87.5 29.7 22.8 83.6 15.6 22.3 60.6 161.4 16.9 8.2 109.7 45.9 332.1 23.9 97.6 39.2 425.3 79.8 29.1 171.0 68.9 4.1 28.1 9.3 33.4 70.3 25.4 3.6 7.1 87.3 4.3 144.7 151.0 157.8 6.6 6.6 33.7 45.5 129.3 108.0 32.0 22.3 19.2 UVRAG VPS38 ENSG00000198382 "UV radiation resistance associated" Q9P2Y5 11 75815210-76144232 "Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 144.6;Microglial cells: 178.9;Oligodendrocytes: 361.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016932 Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "HPA016932: AB_1858707" "unprognostic (3.92e-2)" "unprognostic (1.20e-1)" "unprognostic (1.10e-1)" "unprognostic (4.22e-3)" "unprognostic (2.29e-1)" "unprognostic (1.02e-1)" "unprognostic (1.15e-2)" "unprognostic (2.89e-1)" "unprognostic (2.96e-1)" "unprognostic (3.01e-1)" "unprognostic (7.89e-2)" "unprognostic (2.18e-2)" "unprognostic (6.90e-2)" "unprognostic (1.08e-1)" "unprognostic (1.34e-1)" "unprognostic (6.94e-2)" "unprognostic (3.03e-1)" 32.1 12.8 11.4 17.9 16.9 33.9 20.7 12.1 15.4 13.7 35.9 14.5 10.6 13.3 14.3 10.1 13.3 15.3 10.7 11.4 12.8 11.6 15.3 15.4 26.5 15.0 15.9 12.4 8.2 21.3 7.3 18.2 16.9 10.5 12.4 19.2 8.0 11.4 14.5 11.8 10.6 14.9 16.0 21.4 12.7 7.9 13.9 25.2 12.9 14.7 25.4 13.1 8.9 25.2 10.3 14.4 11.2 9.7 27.2 20.2 16.3 15.0 27.5 17.4 13.8 19.7 18.9 49.5 30.5 20.5 30.7 10.8 19.5 17.5 19.9 27.2 7.8 18.3 12.2 16.8 24.2 30.6 19.1 17.4 14.6 23.8 42.6 13.1 51.0 22.0 19.6 29.7 16.5 24.1 20.9 19.6 11.1 32.1 15.7 17.3 28.5 40.9 14.8 35.0 15.3 10.8 16.6 16.7 13.2 17.1 20.9 27.4 45.3 16.8 12.7 62.4 10.3 18.4 23.3 51.0 7.6 16.0 21.3 5.8 9.9 8.4 7.0 8.8 6.4 23.4 6.1 6.9 16.8 26.6 8.2 6.6 13.9 8.1 11.4 24.0 6.3 4.7 11.4 16.9 12.1 15.4 11.4 12.8 15.0 15.9 16.9 16.0 13.9 25.2 97.3 12.8 21.3 53.8 97.0 9.2 9.4 9.8 26.7 52.2 17.5 19.4 16.1 10.0 11.3 7.3 68.8 37.6 41.6 9.5 7.9 11.5 6.2 13.6 28.1 36.5 5.4 24.6 144.6 8.7 10.3 24.7 34.1 18.5 10.8 16.0 20.0 9.2 17.3 53.8 124.6 10.0 8.2 22.0 50.8 2.6 21.5 46.3 8.8 178.9 45.8 19.0 34.0 89.0 361.8 10.5 11.4 16.1 40.4 12.1 10.8 11.0 6.5 53.1 13.1 27.2 28.6 13.5 19.1 19.4 12.6 32.8 28.1 25.1 10.1 9.1 VAMP3 CEB ENSG00000049245 "Vesicle associated membrane protein 3" Q15836 1 7771296-7781432 "Cancer-related genes, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 260000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (1.09e-2)" "unprognostic (4.03e-1)" "unprognostic (3.39e-3)" "unprognostic (2.95e-1)" "unprognostic (9.15e-3)" "unprognostic (3.86e-3)" "unprognostic (9.49e-3)" "unprognostic (2.00e-1)" "unprognostic (7.16e-2)" "unprognostic (2.36e-1)" "unprognostic (1.83e-3)" "unprognostic (2.17e-1)" "prognostic favorable (2.36e-4)" "unprognostic (1.02e-1)" "unprognostic (2.85e-1)" "unprognostic (9.52e-2)" "unprognostic (3.30e-2)" 108.3 79.2 81.8 50.1 102.7 113.4 76.8 101.2 102.7 73.9 70.8 67.9 63.4 74.1 66.1 82.1 65.1 64.7 78.6 78.7 91.3 77.0 63.6 91.7 44.0 111.4 102.3 78.2 33.0 74.0 46.8 87.1 111.1 60.2 74.1 26.2 45.7 81.7 89.4 71.0 69.7 85.5 97.2 56.7 60.6 43.8 93.6 37.1 67.9 98.9 52.3 86.4 60.8 123.6 92.3 64.3 67.9 81.4 181.9 204.1 47.7 162.5 183.3 170.8 160.5 70.8 116.1 12.1 89.1 205.8 86.9 78.5 75.2 109.9 218.1 9.6 93.5 59.2 56.8 99.3 118.0 35.4 56.2 167.2 80.7 121.8 98.7 168.4 209.6 26.8 61.9 54.5 241.7 41.2 26.7 31.5 30.0 102.9 111.6 21.9 98.7 37.4 133.7 52.4 18.6 70.8 141.2 68.5 152.2 81.1 69.4 37.3 186.9 152.5 52.3 160.0 79.4 44.7 65.2 35.1 174.7 140.9 122.9 63.7 63.0 63.0 15.9 71.7 16.5 13.8 14.9 14.1 43.1 11.2 11.9 13.0 84.0 19.0 65.0 14.0 20.9 30.2 81.8 102.7 101.2 102.7 78.7 91.3 111.4 102.3 111.1 97.2 93.6 123.6 88.0 48.1 46.1 11.8 18.6 43.6 58.2 38.8 50.1 12.5 30.5 29.1 44.8 37.1 31.8 40.5 4.2 85.6 24.2 60.1 64.6 67.9 24.3 24.7 35.4 88.1 31.2 28.8 9.6 50.5 113.7 46.1 26.5 28.8 58.2 31.1 73.2 37.5 78.0 8.4 9.9 42.8 42.7 78.2 63.3 12.5 32.3 65.9 56.9 8.4 72.0 76.0 27.8 12.5 24.4 89.8 44.5 47.0 21.6 62.0 65.5 100.0 29.4 8.6 46.0 52.2 53.0 61.3 49.3 61.7 51.3 114.5 21.3 53.3 43.0 86.1 VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 487.9;Endothelial cells: 337.8;Hepatic stellate cells: 486.2;Kupffer cells: 340.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 364.7;LHCN-M2: 428.9;TIME: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA035082: AB_10610564" "unprognostic (1.92e-1)" "unprognostic (3.09e-2)" "unprognostic (6.09e-2)" "unprognostic (1.13e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-3)" "unprognostic (1.28e-2)" "unprognostic (5.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.49e-2)" "unprognostic (2.22e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (9.61e-3)" "unprognostic (3.46e-2)" "unprognostic (1.71e-2)" "unprognostic (2.60e-1)" 134.0 117.4 71.0 59.9 74.1 41.2 118.4 72.9 89.1 78.6 66.8 76.4 23.3 79.4 33.2 45.3 84.3 58.0 114.7 69.4 76.1 90.0 79.3 134.6 92.7 79.1 71.4 52.8 29.0 14.7 31.9 74.1 74.2 72.8 20.5 2.9 36.9 36.7 217.3 44.5 54.1 77.2 73.8 97.5 54.0 11.4 78.0 50.9 63.8 199.6 41.2 87.1 69.7 71.7 0.8 0.2 2.4 0.0 89.3 155.8 2.4 98.5 155.9 95.5 104.5 39.5 15.1 0.3 2.3 172.2 50.7 1.1 0.0 2.4 42.2 142.9 2.8 1.9 2.5 56.1 187.2 4.5 0.9 108.4 9.6 40.1 1.1 138.9 364.7 61.7 0.4 0.3 428.9 14.5 63.1 13.8 0.1 27.2 0.6 92.4 0.4 2.7 2.7 3.6 0.2 3.4 0.6 27.4 0.5 2.2 3.2 5.1 250.0 2.3 6.7 7.5 0.2 0.1 3.1 2.4 110.5 5.4 65.9 59.1 222.6 176.5 180.5 503.8 171.7 60.7 136.1 135.2 79.0 54.5 102.4 125.1 70.2 94.4 424.9 86.4 248.7 283.0 71.0 74.1 72.9 89.1 69.4 76.1 79.1 71.4 74.2 73.8 78.0 71.7 487.9 19.2 21.2 3.6 43.9 60.8 39.8 104.1 39.3 0.8 14.9 27.3 84.4 71.4 70.1 44.1 0.0 22.9 64.5 38.8 29.4 29.9 1.8 7.7 64.7 337.8 12.6 35.6 0.1 49.1 7.2 148.0 9.7 7.9 44.4 22.2 486.2 198.6 80.3 3.3 0.2 20.5 36.7 340.8 91.5 10.2 192.6 147.8 275.7 4.7 136.0 17.5 112.3 0.5 1.6 44.2 51.9 165.1 68.4 64.7 126.5 91.2 50.6 1.0 59.2 152.2 83.9 5.5 6.6 19.8 45.3 21.6 88.5 19.2 7.8 49.4 VASH1 KIAA1036 ENSG00000071246 "Vasohibin 1" Q7L8A9 14 76761468-76783015 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 67.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 139.7;Early spermatids: 72.8;Late spermatids: 95.3;Microglial cells: 53.4;Rod photoreceptor cells: 98.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 46.1;HEL: 35.1;HUVEC TERT2: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000653 Uncertain "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA000653: AB_1080551" "unprognostic (1.47e-1)" "unprognostic (9.13e-2)" "unprognostic (2.56e-2)" "unprognostic (7.29e-2)" "unprognostic (1.93e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-3)" "unprognostic (1.62e-1)" "unprognostic (9.23e-2)" "unprognostic (6.94e-2)" "prognostic favorable (6.56e-6)" "unprognostic (8.84e-2)" "unprognostic (6.44e-3)" "unprognostic (2.69e-1)" "unprognostic (1.92e-1)" "unprognostic (5.06e-2)" "unprognostic (1.73e-1)" 12.1 18.5 33.2 12.3 34.0 3.0 7.4 30.8 28.8 9.2 21.3 7.9 5.6 11.9 4.2 4.3 8.7 9.0 36.0 28.1 30.8 8.1 3.8 16.0 7.8 38.7 36.3 13.4 5.7 3.9 13.7 19.9 36.6 6.5 5.2 67.6 5.6 4.5 7.5 4.6 8.2 11.5 37.1 18.3 5.1 13.2 36.1 3.2 6.1 7.0 6.6 8.5 6.6 36.4 1.1 5.6 46.1 13.8 11.6 8.4 2.3 4.0 1.3 3.4 1.4 1.5 3.1 2.1 2.8 3.2 4.2 1.3 7.3 1.5 1.0 25.0 5.3 35.1 3.4 1.5 6.9 1.5 3.5 4.5 0.3 1.3 0.2 10.4 85.0 6.2 1.6 0.4 1.1 7.1 1.3 3.0 4.7 1.4 2.8 1.3 4.6 1.0 0.9 2.6 19.1 14.8 4.6 1.8 2.2 9.1 7.8 7.4 24.2 4.3 9.6 5.2 2.0 2.0 1.1 1.2 6.1 11.2 8.3 0.0 0.8 0.0 0.6 2.0 0.5 0.1 0.3 0.3 1.3 0.3 0.2 0.3 0.0 0.2 2.7 2.4 0.1 0.5 33.2 34.0 30.8 28.8 28.1 30.8 38.7 36.3 36.6 37.1 36.1 36.4 17.3 0.0 2.3 7.2 2.7 0.6 0.0 0.3 0.0 9.4 0.9 2.4 10.9 1.5 0.7 1.8 139.7 0.4 11.1 0.0 0.0 0.9 72.8 0.8 7.7 27.5 6.7 0.0 13.4 0.0 0.3 7.6 1.5 0.6 12.0 18.1 31.8 1.2 14.8 0.0 11.9 0.4 2.0 14.2 9.3 95.3 1.8 23.6 1.8 53.4 7.6 15.2 3.1 21.6 21.8 0.3 0.0 3.0 0.4 0.0 0.0 0.2 0.0 98.8 13.1 5.5 10.0 0.8 2.3 0.4 0.1 0.3 1.8 5.7 0.2 0.1 VCP "CDC48, IBMPFD, p97, TERA" ENSG00000165280 "Valosin containing protein" P55072 9 35053928-35072668 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, DNA damage, DNA repair, Transport, Ubl conjugation pathway" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 540.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005593, HPA012728, HPA012814" Supported Enhanced Nucleoplasm,Cytosol No No 34000000 "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Cytosol" "CAB005593: AB_2214638, HPA012728: AB_1858730, HPA012814: AB_1858729" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.15e-2)" "prognostic favorable (7.30e-4)" "unprognostic (5.78e-2)" "unprognostic (1.87e-1)" "unprognostic (2.52e-3)" "unprognostic (1.13e-2)" "unprognostic (3.82e-2)" "unprognostic (1.81e-2)" "unprognostic (2.19e-2)" "unprognostic (3.24e-1)" "prognostic favorable (9.63e-7)" "unprognostic (1.83e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-1)" "unprognostic (9.11e-2)" 59.8 88.4 56.8 33.7 59.0 52.0 54.2 58.9 58.0 57.8 72.0 51.8 33.8 59.0 51.6 84.9 49.4 35.3 117.5 60.4 66.2 59.1 87.5 57.2 42.5 64.4 62.0 46.1 61.2 65.7 57.3 46.0 68.2 54.5 36.5 26.3 63.2 58.9 176.0 64.0 51.8 42.5 62.3 64.1 62.5 45.1 63.7 59.6 49.7 135.3 53.3 57.9 55.3 69.8 167.6 223.8 124.6 57.5 187.4 135.3 98.3 153.8 215.0 244.1 197.6 160.0 60.1 140.8 137.2 242.9 173.1 69.5 253.1 230.7 227.6 146.2 126.0 95.3 216.5 238.0 146.5 92.4 106.2 148.5 136.4 239.2 115.6 104.4 276.2 56.3 97.6 71.4 219.2 154.7 114.3 234.9 152.2 82.7 219.1 80.7 111.8 72.8 204.1 175.7 65.7 84.1 100.4 81.2 45.1 152.2 71.5 60.3 215.5 77.5 112.5 63.7 118.6 41.9 116.5 104.3 139.5 67.0 105.4 142.0 62.7 75.0 58.8 70.0 62.4 59.2 59.0 65.6 75.3 53.0 42.3 44.4 71.1 67.1 80.4 49.8 91.2 111.8 56.8 59.0 58.9 58.0 60.4 66.2 64.4 62.0 68.2 62.3 63.7 69.8 86.5 80.1 73.7 22.9 124.3 77.0 120.8 147.6 111.5 86.6 66.0 47.2 220.4 47.1 115.1 55.2 118.9 276.8 91.0 111.9 74.3 188.6 43.6 97.8 85.6 127.7 84.2 137.0 27.4 187.5 164.7 109.7 133.5 105.8 62.1 106.2 111.0 126.0 133.1 74.0 27.7 108.3 89.5 57.9 65.6 47.0 83.9 81.5 76.5 16.9 159.6 88.7 54.6 18.6 31.4 247.9 69.0 86.9 267.6 118.3 77.2 113.4 102.5 90.0 138.1 74.1 154.9 144.5 118.7 126.2 90.6 540.6 105.4 129.6 96.4 135.6 VEPH1 "FLJ12604, KIAA1692" ENSG00000197415 "Ventricular zone expressed PH domain containing 1" Q14D04 3 157259742-157533619 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 20.2;kidney: 27.0;lung: 29.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 266.0;Alveolar cells type 2: 175.9;Distal tubular cells: 46.9;Early spermatids: 64.5;Late spermatids: 84.7" "Cancer enhanced" "Detected in many" "melanoma: 4.3;renal cancer: 4.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 92.0;hTERT-RPE1: 96.7;HUVEC TERT2: 245.1;TIME: 147.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026645 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli, Cytosol" "HPA026645: AB_1858741" "unprognostic (4.35e-2)" "unprognostic (1.42e-2)" "unprognostic (2.44e-1)" "unprognostic (3.58e-1)" "unprognostic (5.17e-2)" "unprognostic (3.30e-3)" "unprognostic (2.87e-3)" "unprognostic (2.22e-1)" "unprognostic (3.52e-2)" "unprognostic (1.75e-3)" "unprognostic (3.57e-3)" "unprognostic (1.99e-2)" "prognostic favorable (7.75e-9)" "unprognostic (2.03e-1)" "unprognostic (2.57e-1)" "unprognostic (1.15e-4)" "unprognostic (7.49e-2)" 0.4 20.2 0.2 0.1 0.3 2.2 1.9 0.8 0.1 3.1 11.1 0.8 0.7 0.3 17.6 0.0 5.4 0.9 0.2 0.7 0.4 27.0 0.5 29.4 0.0 2.7 1.1 0.2 13.1 2.1 17.1 1.3 2.9 1.4 0.8 0.4 2.5 2.8 0.1 1.5 0.1 0.2 0.4 4.0 0.9 2.9 0.4 0.1 2.0 0.1 0.0 0.4 0.3 0.2 7.3 0.8 16.0 0.0 9.2 33.8 0.0 41.9 92.0 12.2 17.7 1.1 6.4 0.0 16.0 45.3 1.9 0.3 0.5 1.0 67.2 0.2 0.0 7.3 0.8 0.0 2.9 0.0 0.1 9.9 0.7 51.9 10.3 96.7 245.1 0.0 2.5 0.0 33.4 0.9 0.0 0.0 6.6 1.9 6.2 0.0 1.2 0.0 6.1 3.6 0.6 0.0 1.3 1.9 17.0 0.2 70.7 0.1 147.2 48.0 1.6 16.8 58.0 0.0 0.0 0.0 38.6 0.0 11.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.7 0.2 0.3 0.8 0.1 0.7 0.4 2.7 1.1 2.9 0.4 0.4 0.2 0.1 266.0 175.9 1.6 0.5 1.8 0.2 0.0 0.0 0.2 4.5 3.7 0.5 22.8 14.3 31.3 2.1 1.8 0.2 1.2 46.9 6.9 64.5 11.1 0.5 0.9 0.0 0.0 2.8 10.1 0.1 0.9 0.0 4.4 0.0 0.8 0.0 0.0 0.2 0.0 3.3 0.4 0.0 0.0 0.3 84.7 1.5 2.3 28.4 0.0 0.7 1.5 0.0 0.0 0.9 1.8 3.2 0.4 0.0 0.3 0.0 28.7 8.1 0.5 0.0 0.1 1.3 0.3 0.9 0.0 0.4 0.0 0.6 0.9 0.8 0.2 VSIG1 "GPA34, MGC44287" ENSG00000101842 "V-set and immunoglobulin domain containing 1" Q86XK7 X 108044970-108079184 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "stomach 1: 193.6" "Cell type enriched" "Detected in some" 10 "Gastric mucus-secreting cells: 333.8" "Group enriched" "Detected in many" 17 "lung cancer: 8.7;pancreatic cancer: 17.7;stomach cancer: 31.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 12.0;T-reg: 12.9" "Lineage enriched" "Detected in many" 4 "T-cells: 12.9" "Cell line enhanced" "Detected in some" "HBEC3-KT: 3.5;HUVEC TERT2: 7.4;PC-3: 2.3;TIME: 1.7" "Not detected" "Not detected" "HPA001445, HPA036310, HPA036311" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 4: Stomach - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Vesicles, Cytosol" "HPA001445: AB_10669749, HPA036310: AB_10670795, HPA036311: AB_10673350" "unprognostic (4.33e-3)" "unprognostic (4.60e-2)" "unprognostic (3.22e-2)" "unprognostic (1.60e-1)" "unprognostic (2.51e-1)" "unprognostic (4.80e-2)" "unprognostic (3.25e-2)" "unprognostic (9.79e-2)" "unprognostic (4.58e-1)" "unprognostic (2.35e-2)" "unprognostic (2.11e-2)" "unprognostic (1.25e-1)" "unprognostic (6.31e-7)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (2.19e-2)" "unprognostic (2.23e-3)" 0.0 0.1 0.1 1.3 0.3 0.5 0.1 0.2 0.3 0.0 0.2 0.2 1.2 0.1 0.3 0.2 0.0 8.4 0.0 0.2 0.2 0.1 0.1 1.0 1.9 0.1 0.1 0.0 0.2 0.0 2.6 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.4 0.5 0.0 0.0 0.8 193.6 47.7 0.1 0.8 0.1 0.0 1.6 8.9 0.1 0.1 0.1 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.0 1.1 0.0 7.4 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.2 0.6 2.3 0.2 0.0 0.0 0.3 0.6 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.1 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 1.0 0.0 3.8 2.8 8.1 3.6 0.0 1.3 12.0 5.8 0.3 0.1 0.1 0.1 12.9 2.6 0.1 0.3 0.2 0.3 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.2 25.6 11.0 1.0 2.4 0.6 0.9 0.7 0.0 0.9 0.2 0.1 0.5 1.5 0.7 0.0 0.0 0.0 0.1 0.4 0.0 2.9 6.1 1.1 0.1 1.0 0.0 0.0 4.1 4.6 0.0 0.6 333.8 0.2 2.5 0.0 0.0 0.0 0.1 0.0 1.4 0.3 0.0 0.0 0.4 10.8 0.6 0.7 0.0 0.0 0.3 0.1 1.0 0.0 0.1 32.9 0.0 0.0 1.0 0.6 0.0 0.0 0.9 0.8 0.0 1.1 0.2 1.0 0.6 0.0 0.0 0.1 4.5 0.2 0.1 3.8 VWF F8VWF ENSG00000110799 "Von Willebrand factor" P04275 12 5948877-6124770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 904.3;Endothelial cells: 737.5;Hepatic stellate cells: 424.4" "Cancer enhanced" "Detected in all" "renal cancer: 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "HUVEC TERT2: 560.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001694, HPA001815, HPA002082, CAB072874, CAB072875" Supported "Secreted to blood" NA NA 28300000000 5600000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB001694: , CAB072874: AB_2665726, CAB072875: AB_2665727, HPA001815: AB_611880, HPA002082: AB_1080575" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-3)" "unprognostic (7.09e-2)" "unprognostic (4.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.92e-2)" "unprognostic (4.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.55e-1)" "unprognostic (3.12e-1)" "unprognostic (2.73e-3)" 151.9 5.9 40.0 20.2 38.8 0.8 117.3 32.9 31.4 46.0 29.2 32.7 12.8 51.1 10.6 21.9 45.7 30.2 137.8 27.4 32.3 9.7 2.1 106.2 22.8 37.6 37.4 22.0 15.0 27.3 6.3 72.7 41.7 27.4 9.2 2.9 18.1 19.2 57.0 23.5 34.5 44.2 32.2 44.1 25.7 10.8 52.4 7.0 50.8 51.6 9.5 39.7 35.5 37.1 0.0 0.0 0.0 0.0 0.7 0.6 0.5 0.0 0.6 0.2 0.4 0.0 0.3 0.0 1.2 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 560.9 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.3 0.5 0.4 0.0 0.1 10.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 40.0 38.8 32.9 31.4 27.4 32.3 37.6 37.4 41.7 32.2 52.4 37.1 904.3 12.8 25.7 3.6 1.0 6.6 0.6 1.3 4.6 0.0 4.5 4.7 112.2 1.5 1.7 11.0 0.0 1.1 2.6 0.0 0.0 0.5 6.8 2.0 1.6 737.5 0.0 2.7 2.9 0.0 0.9 21.1 0.0 2.1 5.7 0.1 424.4 3.3 0.5 0.0 2.2 0.0 4.1 5.3 3.4 15.5 5.9 2.6 5.4 75.9 0.3 0.7 0.0 1.5 4.2 0.0 0.0 0.7 0.0 1.3 0.0 0.1 1.0 1.7 0.0 12.4 34.7 2.9 5.7 4.7 4.3 1.0 2.0 10.6 0.0 1.7 WASHC4 "KIAA1033, SWIP" ENSG00000136051 "WASH complex subunit 4" Q2M389 12 105107324-105169130 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 44.1;Endometrial stromal cells: 48.3;Hofbauer cells: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045666, HPA046737" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA045666: AB_2679411, HPA046737: AB_2679778" "unprognostic (2.68e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (4.85e-2)" "unprognostic (2.76e-1)" "unprognostic (1.10e-1)" "unprognostic (4.41e-1)" "unprognostic (9.79e-3)" "unprognostic (1.32e-2)" "unprognostic (3.14e-2)" "unprognostic (1.24e-2)" "unprognostic (1.81e-1)" "unprognostic (1.49e-2)" "unprognostic (2.96e-1)" "unprognostic (4.61e-2)" "unprognostic (1.87e-1)" "unprognostic (1.03e-1)" "unprognostic (3.86e-2)" 22.4 21.1 9.4 30.9 13.8 23.8 20.8 13.8 12.2 20.7 11.8 16.1 15.3 20.1 19.9 15.1 13.1 22.6 14.3 9.1 13.8 23.5 29.7 20.2 44.0 17.8 13.0 22.8 18.3 20.4 8.5 30.5 18.4 19.2 18.4 15.4 16.1 15.8 12.2 31.2 18.4 19.8 15.2 32.9 17.9 12.1 14.5 18.0 22.1 14.2 39.5 17.6 12.6 22.1 24.0 28.2 24.6 18.2 56.3 56.6 29.5 36.5 41.5 41.7 38.0 20.2 13.5 53.4 19.8 61.0 26.5 21.9 21.5 22.3 33.5 19.2 15.3 11.1 25.6 16.8 38.4 30.9 20.5 45.7 25.7 37.3 30.4 45.1 68.7 18.1 22.1 18.6 45.9 12.1 17.1 32.6 30.1 16.8 23.5 32.7 32.8 16.6 55.6 27.5 15.4 19.0 37.7 26.4 37.9 31.0 19.6 32.9 84.1 49.8 13.6 32.1 23.9 23.3 23.9 42.7 35.4 26.1 51.4 21.3 15.1 9.2 3.0 18.4 4.4 16.2 4.7 4.1 11.9 12.9 4.9 4.7 16.7 8.0 34.2 5.8 3.5 6.9 9.4 13.8 13.8 12.2 9.1 13.8 17.8 13.0 18.4 15.2 14.5 22.1 37.5 35.3 24.3 0.0 25.3 0.0 0.0 0.0 0.0 0.0 16.4 11.0 0.0 0.0 11.8 44.1 0.0 24.1 17.5 0.0 19.6 25.8 0.0 23.8 48.3 18.0 0.0 0.0 0.0 22.1 28.0 14.6 0.0 31.7 26.5 30.7 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.3 0.0 0.0 26.9 0.0 0.0 0.0 0.0 24.2 0.0 0.0 5.2 0.0 0.0 41.8 17.5 0.0 0.0 0.0 17.4 0.0 0.0 0.0 0.0 32.0 8.9 29.1 0.0 0.0 WDFY3 "ALFY, KIAA0993, ZFYVE25" ENSG00000163625 "WD repeat and FYVE domain containing 3" Q8IZQ1 4 84669597-84966690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Developmental protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 44.9" "Group enriched" "Detected in many" 5 "Astrocytes: 241.0;Excitatory neurons: 231.0;Inhibitory neurons: 248.7;Microglial cells: 209.9;Oligodendrocyte precursor cells: 262.9;Oligodendrocytes: 440.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "TIME: 57.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042734, HPA048572" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Nucleoli, Plasma membrane" "HPA042734: AB_2678135, HPA048572: AB_2680447" "unprognostic (7.14e-2)" "unprognostic (6.02e-2)" "unprognostic (7.68e-2)" "unprognostic (1.60e-1)" "unprognostic (1.84e-2)" "unprognostic (2.48e-1)" "unprognostic (2.86e-2)" "unprognostic (3.36e-1)" "unprognostic (1.01e-1)" "unprognostic (4.33e-2)" "unprognostic (3.36e-1)" "unprognostic (7.12e-2)" "prognostic favorable (3.64e-5)" "prognostic unfavorable (9.35e-4)" "unprognostic (2.79e-1)" "unprognostic (4.41e-2)" "unprognostic (4.95e-2)" 8.6 8.6 14.8 7.6 31.7 14.4 8.7 26.8 22.9 8.5 4.7 5.7 3.6 8.2 6.4 7.4 8.2 8.8 5.7 16.3 15.6 20.1 5.6 7.4 2.6 30.6 30.4 13.6 9.0 16.3 6.5 11.8 28.7 8.6 5.6 26.2 7.2 7.4 5.9 10.8 4.7 8.5 21.7 7.8 5.6 8.1 25.6 3.4 11.7 13.2 2.3 8.7 5.7 44.9 11.9 7.8 14.3 7.9 24.8 19.3 9.0 11.2 11.8 11.5 10.3 9.1 9.6 0.0 11.3 18.8 12.3 5.9 15.4 12.3 14.6 7.9 4.9 7.5 9.0 5.5 9.4 5.9 13.7 14.2 10.9 15.0 15.1 13.9 37.1 6.0 7.5 35.3 21.4 8.5 5.7 1.4 7.4 11.4 4.0 8.4 11.4 1.8 19.6 15.6 16.8 7.8 13.8 15.1 7.5 13.5 7.9 14.4 57.0 15.1 14.9 8.5 14.1 0.1 0.0 0.0 10.2 5.0 16.9 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.1 14.8 31.7 26.8 22.9 16.3 15.6 30.6 30.4 28.7 21.7 25.6 44.9 28.5 19.2 12.9 241.0 1.0 14.7 9.1 12.4 11.4 46.6 13.8 11.3 18.2 20.0 14.7 16.5 35.5 11.8 0.5 6.5 1.9 8.6 6.7 27.1 27.8 20.1 9.1 1.3 231.0 7.3 6.9 19.5 15.3 43.4 0.0 31.0 17.9 8.1 20.5 28.6 248.7 7.8 20.3 43.1 14.1 10.1 18.3 29.9 7.2 209.9 19.7 28.7 0.0 262.9 440.4 10.7 6.5 24.5 0.2 13.6 4.8 18.4 15.5 41.9 26.3 30.0 22.8 11.4 7.3 14.1 16.1 14.5 1.8 15.0 6.7 13.6 WDR37 KIAA0982 ENSG00000047056 "WD repeat domain 37" Q9Y2I8 10 1049538-1132384 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 184.8;Late spermatids: 92.9;NK-cells: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037376, HPA037565" Enhanced Approved "Intermediate filaments" No No "Cluster 48: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 34: Spermatids - Unknown function" "Intermediate filaments" "HPA037376: AB_10672789, HPA037565: AB_10696937" "unprognostic (1.50e-2)" "unprognostic (2.07e-1)" "unprognostic (9.08e-3)" "unprognostic (8.51e-3)" "unprognostic (1.81e-1)" "prognostic favorable (1.75e-5)" "unprognostic (2.59e-3)" "unprognostic (3.56e-2)" "unprognostic (1.80e-1)" "unprognostic (1.62e-2)" "prognostic favorable (1.46e-6)" "unprognostic (3.16e-1)" "unprognostic (4.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.34e-5)" "unprognostic (5.98e-2)" 8.4 16.5 10.4 9.3 10.5 22.2 7.8 0.4 18.7 8.1 2.0 8.9 7.3 7.9 8.9 9.1 7.8 6.1 17.6 13.1 2.5 8.7 10.3 10.3 12.5 1.5 1.9 9.7 10.1 9.8 14.6 6.3 2.9 8.1 6.7 14.9 7.6 5.1 18.3 11.5 11.2 6.6 0.0 21.0 10.3 21.2 3.1 10.3 9.5 15.7 9.8 7.0 7.9 9.7 12.4 9.0 11.6 9.4 10.9 15.8 8.2 15.5 8.4 9.5 9.4 11.3 10.4 6.1 9.2 20.3 2.0 11.2 6.1 18.1 8.1 7.4 10.0 14.8 9.6 7.7 7.7 8.8 16.0 19.8 13.6 13.6 4.8 11.3 21.0 12.1 9.1 7.3 15.2 10.9 9.8 6.9 6.4 9.6 4.8 14.9 6.5 10.5 13.2 13.8 5.2 10.1 7.2 13.3 11.9 8.8 12.8 17.9 27.7 7.5 2.5 24.8 12.5 13.4 13.3 8.2 17.4 9.9 5.4 6.0 4.8 3.5 10.0 6.2 8.7 5.5 5.6 7.4 5.2 4.4 6.3 7.3 3.8 11.2 7.1 4.8 5.3 5.2 10.4 10.5 0.4 18.7 13.1 2.5 1.5 1.9 2.9 0.0 3.1 9.7 10.5 3.2 8.1 33.6 14.5 13.4 13.0 7.5 10.2 16.3 8.4 7.2 23.3 5.7 7.9 11.0 12.5 6.2 27.4 8.6 0.0 4.8 184.8 5.7 8.6 13.6 10.7 6.5 65.3 6.1 4.2 9.0 13.3 11.1 12.0 7.3 30.7 7.0 9.0 8.4 59.7 8.1 8.2 18.8 13.7 92.9 12.5 14.8 16.0 43.1 23.7 5.3 86.5 36.7 47.3 9.5 8.3 18.0 9.6 13.6 7.2 4.8 4.9 14.7 6.6 13.0 8.5 11.6 14.3 11.9 12.4 11.4 19.1 10.1 5.9 19.7 WSB1 "DKFZp564A122, DKFZp564B0482, SWIP1" ENSG00000109046 "WD repeat and SOCS box containing 1" Q9Y6I7 17 27294076-27315926 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003293 Approved Approved Mitochondria NA Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA003293: AB_1858863" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-1)" "unprognostic (2.14e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (4.07e-5)" "unprognostic (2.59e-2)" "unprognostic (5.40e-3)" "unprognostic (2.74e-1)" "unprognostic (9.22e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-7)" "unprognostic (1.44e-1)" "unprognostic (3.18e-1)" "unprognostic (1.62e-1)" "unprognostic (3.74e-2)" 41.9 22.1 14.1 45.9 35.7 48.7 35.7 22.9 26.9 47.0 5.2 40.7 28.6 49.4 24.6 27.7 45.9 39.6 32.5 14.1 35.9 29.0 15.6 58.3 34.5 38.7 22.7 47.7 29.6 19.0 23.8 75.0 40.6 27.6 30.9 76.0 27.4 32.1 23.0 23.2 33.7 44.8 17.0 69.9 32.7 21.6 33.2 24.8 28.8 16.1 35.2 32.8 39.1 80.0 30.8 21.3 65.3 37.5 40.3 49.7 69.7 26.6 37.9 20.6 39.6 32.0 12.2 30.6 29.6 36.6 26.2 28.4 40.0 19.6 30.9 85.3 33.1 48.7 41.9 32.7 75.7 34.1 69.2 60.2 26.3 30.1 18.4 31.5 83.1 31.7 49.8 28.6 36.9 19.4 44.4 38.4 19.4 17.1 17.3 35.5 35.9 18.5 31.1 24.6 20.9 28.8 27.8 27.3 36.7 77.8 22.1 44.5 46.5 25.3 19.2 34.8 26.4 12.8 34.9 31.2 23.9 26.8 23.4 75.0 41.1 71.5 21.6 70.3 26.1 22.1 18.1 24.2 65.5 25.3 17.0 19.7 37.1 21.4 82.5 21.5 30.2 26.4 14.1 35.7 22.9 26.9 14.1 35.9 38.7 22.7 40.6 17.0 33.2 80.0 300.4 221.2 476.1 189.7 245.4 249.2 185.6 138.4 253.8 91.9 186.7 147.7 67.5 144.4 194.2 239.1 348.2 360.7 183.2 222.7 27.4 124.9 153.0 201.2 187.6 254.9 194.4 148.1 229.5 65.1 217.2 284.6 190.6 301.5 163.5 436.3 316.6 43.3 228.2 82.4 267.8 191.5 162.8 412.6 288.9 26.6 141.4 358.9 197.5 206.1 153.2 170.5 112.3 349.3 658.2 76.7 185.4 122.6 144.9 196.3 178.7 30.7 137.5 381.4 124.9 243.8 221.9 119.6 104.8 202.2 280.3 714.5 183.9 98.5 133.6 148.9 XIRP2 CMYA3 ENSG00000163092 "Xin actin binding repeat containing 2" A4UGR9 2 166888480-167259753 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 202.3;skeletal muscle: 1034.1;tongue: 543.2" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 1907.2" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;HUVEC TERT2: 4.2;U-2197: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034813, HPA074599" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" Nucleoplasm "HPA034813: AB_10602588, HPA074599: " "unprognostic (5.27e-4)" "unprognostic (5.96e-3)" "unprognostic (7.42e-2)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (2.56e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 202.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.9 0.0 0.0 8.0 0.0 1034.1 1.2 0.1 0.0 0.0 0.5 0.1 3.0 0.0 0.1 0.3 543.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.1 0.3 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1907.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 10.1 0.0 0.0 1.9 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 23.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.4 5.8 1.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 20.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 20.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" 25.2 13.5 11.9 10.5 12.7 4.1 21.8 12.7 14.3 17.4 11.5 21.8 24.8 16.0 17.9 22.7 13.9 18.9 13.1 11.7 13.7 27.9 50.6 17.2 6.2 13.9 13.2 12.4 26.5 20.0 6.1 41.7 13.5 15.0 22.7 8.3 21.0 11.9 8.3 16.7 23.7 15.9 14.2 27.4 21.3 19.0 14.3 10.5 22.0 14.6 8.8 20.3 11.5 14.1 42.7 20.8 64.3 50.6 37.8 46.5 75.6 27.9 56.2 32.0 43.7 49.9 30.7 0.1 28.8 47.3 41.0 24.3 60.8 49.1 62.3 0.2 20.7 12.6 19.4 35.1 30.6 9.9 21.7 35.7 51.7 48.5 53.6 39.8 109.8 7.0 56.1 18.4 46.1 29.3 6.0 13.0 40.9 26.0 26.4 7.4 50.6 3.6 46.8 49.6 13.1 15.3 57.5 42.9 37.1 42.3 29.7 20.5 95.6 78.4 86.2 59.9 75.8 15.7 8.3 2.6 29.7 13.8 47.6 20.2 0.0 1.0 2.2 0.0 1.5 0.1 0.4 1.2 0.0 0.0 1.0 1.7 0.0 1.1 0.0 0.0 0.1 0.6 11.9 12.7 12.7 14.3 11.7 13.7 13.9 13.2 13.5 14.2 14.3 14.1 120.3 25.6 36.8 18.9 3.3 60.2 46.8 21.4 50.1 6.0 38.1 26.7 18.2 24.3 31.3 29.5 6.2 37.1 52.9 40.3 3.9 29.6 29.4 32.8 35.0 91.0 22.8 12.0 0.4 39.2 26.6 35.4 57.6 43.6 13.9 35.9 39.7 44.9 4.9 3.3 10.3 37.2 14.2 5.4 14.7 11.7 18.3 5.0 24.9 46.9 2.0 16.8 16.5 31.7 30.2 51.0 28.8 12.8 28.9 65.4 33.1 45.6 29.0 8.6 19.7 35.9 23.8 20.3 13.6 53.1 49.7 45.6 27.5 42.4 36.7 66.6 YPEL2 FKSG4 ENSG00000175155 "Yippee like 2" Q96QA6 17 59331655-59401729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 83.3" "Cell type enhanced" "Detected in all" "Horizontal cells: 489.6;Oligodendrocytes: 237.8;Rod photoreceptor cells: 862.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 28.2;HSkMC: 20.0;SuSa: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030501, HPA045621" Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA030501: AB_10602683, HPA045621: " "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (2.22e-1)" "unprognostic (5.73e-2)" "unprognostic (4.57e-2)" "unprognostic (1.16e-1)" "unprognostic (7.75e-3)" "unprognostic (1.52e-1)" "unprognostic (2.69e-2)" "unprognostic (1.53e-1)" "unprognostic (8.53e-2)" "unprognostic (1.01e-1)" "unprognostic (3.00e-1)" "unprognostic (1.85e-1)" "unprognostic (3.04e-1)" 17.4 9.8 12.5 11.0 17.3 28.4 11.9 13.8 19.7 9.1 3.2 11.3 9.6 9.2 10.2 11.5 11.6 15.0 24.7 12.2 15.3 13.5 19.6 12.4 10.6 16.4 13.8 6.9 10.8 13.3 9.2 15.0 15.3 7.6 10.3 83.3 10.6 11.3 31.0 12.0 9.5 16.7 10.5 12.3 9.6 8.5 14.3 7.8 11.5 22.7 9.7 10.4 9.0 30.4 0.2 3.0 3.2 1.9 18.4 17.3 6.5 1.5 6.3 1.5 2.5 1.0 3.4 2.8 15.8 3.5 1.9 0.2 1.5 1.9 2.0 28.2 4.2 0.7 2.1 3.2 3.7 4.3 0.7 20.0 4.2 2.8 3.0 5.9 17.3 3.6 1.1 3.3 1.3 2.5 1.2 5.5 1.2 6.2 0.4 1.3 1.0 5.9 5.5 2.6 2.6 10.4 1.6 1.5 4.5 35.5 2.9 6.2 12.0 1.6 4.8 1.2 0.4 4.6 1.5 0.9 3.6 3.2 2.1 13.5 12.6 7.0 3.4 17.2 2.1 6.2 5.5 4.2 7.1 8.6 10.4 7.3 10.5 13.0 17.5 2.5 10.3 7.6 12.5 17.3 13.8 19.7 12.2 15.3 16.4 13.8 15.3 10.5 14.3 30.4 44.0 22.4 15.5 18.3 20.0 19.8 6.8 7.5 27.9 75.9 59.8 23.6 43.2 44.3 15.8 27.6 196.0 1.3 17.5 32.1 7.9 46.0 2.5 29.5 15.0 64.4 30.5 10.3 40.0 16.2 11.1 40.2 43.3 52.8 4.5 130.8 29.3 31.2 9.2 489.6 35.4 42.9 14.2 58.5 37.4 6.2 19.3 40.6 24.9 37.5 34.4 25.1 12.3 13.6 237.8 15.9 25.2 15.8 8.7 21.5 17.9 27.3 25.5 862.6 39.5 17.6 56.8 2.3 14.0 13.6 26.6 2.2 20.2 75.6 17.4 13.3 ZBED6 ENSG00000257315 "Zinc finger BED-type containing 6" P86452 1 203795714-203854999 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068807 Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Centriolar satellite" "HPA068807: AB_2686040" "unprognostic (1.79e-1)" "unprognostic (4.96e-3)" "unprognostic (4.81e-2)" "unprognostic (2.73e-1)" "unprognostic (6.94e-2)" "unprognostic (3.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.72e-1)" "unprognostic (1.24e-2)" "unprognostic (2.28e-3)" "unprognostic (7.54e-3)" "unprognostic (1.56e-1)" "unprognostic (4.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.59e-1)" "unprognostic (4.15e-3)" "unprognostic (1.47e-2)" 5.0 4.3 3.4 3.6 7.9 3.0 3.7 6.7 4.5 6.4 8.9 3.3 6.0 5.9 3.2 3.9 4.0 4.4 2.7 2.8 5.6 4.5 5.7 3.7 4.0 5.8 5.7 6.9 7.0 3.9 3.2 6.0 5.9 3.2 3.8 5.6 4.6 4.1 4.3 4.9 3.6 3.8 2.5 5.0 4.9 2.5 6.8 5.3 5.0 6.2 4.3 3.4 3.7 11.9 4.4 7.2 10.2 5.0 7.6 16.8 4.1 6.2 15.2 4.4 4.9 1.7 4.4 3.0 1.3 10.3 2.6 7.0 3.3 5.2 7.1 8.3 2.7 6.2 7.7 1.4 3.8 4.7 4.4 9.2 2.4 5.8 6.3 9.7 12.2 3.8 7.6 8.7 6.5 3.0 3.2 3.4 2.4 2.1 2.7 2.5 9.1 3.3 2.5 7.3 2.1 10.2 7.4 6.6 2.8 8.7 10.7 5.0 21.4 6.7 6.3 3.2 4.4 4.9 2.0 0.9 7.7 2.4 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 3.4 7.9 6.7 4.5 2.8 5.6 5.8 5.7 5.9 2.5 6.8 11.9 1.5 9.6 6.3 0.0 8.9 15.9 35.3 11.3 6.8 15.0 0.4 0.5 2.5 8.6 15.2 0.0 31.3 14.5 5.4 15.7 0.0 0.1 1.0 2.2 3.0 14.5 18.5 12.0 0.0 0.0 13.9 16.0 11.2 2.3 33.0 1.1 10.0 4.6 6.0 11.8 0.0 14.0 8.2 9.3 19.6 1.0 19.9 8.9 14.2 0.0 5.8 14.7 15.5 0.0 0.0 0.1 14.5 15.1 3.8 43.0 35.1 0.1 11.0 21.1 26.3 37.3 15.2 6.5 8.2 5.6 17.0 34.9 12.0 1.5 14.2 56.9 ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type palmitoyltransferase 13" Q8IUH4 11 19117099-19176422 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Urothelial cells: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "Golgi apparatus" "HPA016759: AB_1858993, HPA018791: AB_1858992" "unprognostic (1.43e-2)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (1.11e-3)" "unprognostic (2.95e-2)" "unprognostic (1.34e-2)" "unprognostic (1.55e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (6.95e-3)" "unprognostic (1.15e-1)" "unprognostic (7.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" 4.8 5.7 5.2 7.8 5.2 9.7 8.9 6.6 7.1 9.3 6.6 16.9 11.2 6.7 5.1 37.2 12.9 8.7 9.1 5.4 5.7 9.2 2.2 6.1 9.6 5.5 5.0 5.3 11.2 14.9 11.7 6.2 5.8 8.2 18.2 16.1 10.2 5.4 1.6 18.8 11.3 6.1 5.3 5.7 18.5 14.4 5.0 11.7 8.7 2.9 22.4 22.4 15.4 5.2 41.6 19.3 18.0 15.5 6.3 7.2 17.3 19.4 17.8 21.3 24.4 11.7 9.7 21.1 13.1 16.3 47.9 61.3 26.0 12.8 23.3 26.4 22.6 11.1 12.6 9.7 14.6 15.2 18.5 8.3 14.7 9.0 12.5 19.9 136.8 28.9 10.7 10.3 22.1 13.5 19.6 12.2 15.1 38.7 17.6 21.3 25.0 5.0 21.9 27.0 31.3 23.0 23.2 28.0 10.7 17.3 13.2 17.6 39.6 18.9 13.2 29.2 15.8 8.7 28.5 19.2 22.6 15.5 33.6 11.6 4.7 32.7 8.5 7.9 7.8 8.7 6.6 9.6 5.9 5.5 6.2 8.3 6.0 6.3 6.4 5.6 9.4 4.6 5.2 5.2 6.6 7.1 5.4 5.7 5.5 5.0 5.8 5.3 5.0 5.2 8.1 9.6 10.7 28.7 9.6 24.2 22.3 27.2 14.2 12.0 7.5 4.8 34.1 12.8 41.3 16.5 10.4 8.7 10.6 20.1 5.9 25.1 120.5 21.5 6.6 11.3 15.6 11.6 27.2 19.2 18.8 9.2 24.5 30.8 12.0 16.2 12.8 0.9 6.1 16.8 34.9 24.7 36.7 6.8 8.3 46.6 7.8 6.2 3.6 9.4 20.8 52.8 18.6 19.6 20.9 20.4 16.4 2.2 10.4 47.4 15.5 3.5 57.0 8.8 0.0 5.4 7.4 58.1 31.7 21.3 36.2 6.3 11.4 7.7 21.4 103.0 ZEB1 "AREB6, BZP, FECD6, NIL-2-A, PPCD3, TCF8, ZEB, Zfhep, Zfhx1a" ENSG00000148516 "Zinc finger E-box binding homeobox 1" P37275 10 31318495-31529814 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 287.8;Excitatory neurons: 276.1;Inhibitory neurons: 261.9;Microglial cells: 479.7;Oligodendrocyte precursor cells: 968.6" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 113.1;TIME: 87.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027524, CAB058686, CAB079943" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Nucleoli "CAB058686: AB_2665569, CAB079943: , HPA027524: AB_1844977" "unprognostic (1.54e-1)" "unprognostic (3.08e-1)" "unprognostic (3.42e-2)" "unprognostic (1.04e-1)" "unprognostic (4.85e-2)" "unprognostic (7.40e-2)" "unprognostic (1.34e-2)" "unprognostic (5.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.96e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (7.34e-6)" "unprognostic (5.59e-3)" "unprognostic (1.19e-1)" "unprognostic (1.62e-2)" "unprognostic (1.66e-2)" 26.6 8.6 16.4 12.9 16.2 8.6 16.8 14.0 20.1 33.2 9.9 49.2 6.0 38.7 13.4 11.7 18.6 20.0 34.8 15.2 22.8 7.5 10.4 16.0 9.6 21.1 19.2 9.3 3.8 3.4 7.9 17.5 21.2 14.5 12.3 14.8 8.0 26.9 54.4 7.0 11.8 39.9 16.8 8.1 18.1 10.1 18.2 29.9 11.2 60.5 9.7 24.4 16.4 18.5 0.1 11.1 35.1 43.9 58.4 113.1 0.0 32.7 44.9 6.6 9.3 0.2 0.1 11.3 15.6 39.6 9.3 0.0 14.9 0.0 11.8 19.1 7.9 0.0 7.0 6.3 44.4 9.8 0.3 53.4 0.1 19.6 17.6 21.4 54.9 9.5 7.5 14.4 42.7 0.1 33.7 6.2 2.3 0.0 6.6 11.6 66.0 5.1 12.9 0.0 0.9 15.6 11.1 0.0 0.0 7.2 0.0 6.7 87.7 40.8 9.4 10.0 16.7 9.1 6.3 12.8 10.9 0.0 4.2 4.9 0.0 5.4 2.4 0.0 3.2 4.1 3.2 1.7 1.3 3.1 6.8 3.5 8.5 6.6 0.0 3.1 5.0 1.6 16.4 16.2 14.0 20.1 15.2 22.8 21.1 19.2 21.2 16.8 18.2 18.5 104.4 0.0 7.7 212.9 34.6 11.2 3.0 2.0 0.6 42.7 1.4 2.8 106.3 1.5 3.6 1.8 45.9 0.3 22.0 0.0 0.0 2.1 110.1 7.2 287.8 110.6 0.0 12.2 276.1 2.7 0.5 66.1 2.0 6.5 1.3 17.0 49.6 13.4 1.2 10.1 261.9 0.0 0.0 3.8 25.6 141.8 30.7 6.3 26.6 479.7 10.7 7.2 7.2 968.6 7.3 2.5 0.0 102.0 33.2 3.7 0.0 1.6 1.5 43.4 78.9 99.2 74.2 17.4 15.7 1.1 8.7 0.7 36.2 12.0 0.0 3.8 ZFHX4 "FLJ20980, ZFH4" ENSG00000091656 "Zinc finger homeobox 4" Q86UP3 8 76681239-76867281 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.3" "Cell type enhanced" "Detected in many" "Astrocytes: 358.5;Bipolar cells: 87.2;Oligodendrocyte precursor cells: 234.2;Oligodendrocytes: 222.6;Skeletal myocytes: 120.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 16.8;TIME: 33.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023837 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli fibrillar center" "HPA023837: AB_1859013" "unprognostic (2.00e-1)" "unprognostic (8.19e-2)" "unprognostic (2.63e-3)" "unprognostic (6.14e-8)" "unprognostic (3.81e-1)" "unprognostic (1.17e-1)" "unprognostic (7.61e-2)" "unprognostic (2.61e-2)" "unprognostic (3.79e-2)" "unprognostic (9.15e-4)" "unprognostic (3.18e-2)" "unprognostic (1.17e-3)" "unprognostic (6.20e-7)" "unprognostic (3.50e-3)" "unprognostic (2.51e-1)" "unprognostic (4.50e-4)" "unprognostic (5.89e-4)" 3.0 3.6 7.5 0.5 12.0 0.0 2.1 0.9 9.3 3.2 0.0 3.2 0.0 0.8 3.2 0.3 0.6 0.9 0.4 6.0 18.9 0.3 2.8 0.1 0.3 11.3 23.3 1.9 0.2 0.2 2.8 0.1 17.7 1.0 0.5 2.2 0.6 5.5 2.8 0.4 0.3 1.1 7.0 0.1 0.8 6.7 15.3 0.6 0.3 3.1 0.0 2.7 2.6 15.0 0.0 2.2 3.8 0.0 7.2 8.7 0.0 3.3 4.6 3.8 3.9 0.0 0.0 0.0 5.8 5.7 1.7 0.4 7.8 1.0 7.6 0.0 10.3 0.1 0.0 0.0 1.9 0.0 0.5 16.8 0.4 9.5 3.0 6.5 0.7 0.0 0.1 0.3 7.0 0.0 0.0 0.0 0.6 0.4 7.1 0.0 6.8 0.0 5.8 0.0 0.0 6.5 0.0 0.8 0.0 0.0 0.9 0.0 33.4 3.7 5.6 10.6 7.4 10.9 1.2 0.0 1.8 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 12.0 0.9 9.3 6.0 18.9 11.3 23.3 17.7 7.0 15.3 15.0 5.4 0.0 1.5 358.5 0.3 0.5 0.1 1.0 2.2 87.2 2.4 2.2 4.0 42.9 0.3 5.5 2.1 0.1 0.2 0.0 0.0 0.1 70.0 0.0 1.1 2.0 0.0 0.0 13.7 0.0 0.0 37.5 0.0 0.0 0.0 0.1 1.1 30.5 0.4 5.0 12.6 0.2 0.0 0.6 1.8 24.3 13.7 0.7 0.0 29.0 0.0 15.0 0.0 234.2 222.6 0.0 0.0 21.4 0.1 0.3 0.0 0.3 0.3 5.8 0.0 120.6 8.1 12.4 2.3 1.2 1.1 0.0 0.6 10.0 0.0 0.9 ZFPM2 "FOG2, hFOG-2, ZC2HC11B, ZNF89B" ENSG00000169946 "Zinc finger protein, FOG family member 2" Q8WW38 8 104590733-105804539 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Gonadal differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.2;ovary: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 115.2;Excitatory neurons: 524.4;Inhibitory neurons: 159.8;Microglial cells: 152.7;Oligodendrocyte precursor cells: 689.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 64.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.4;BJ hTERT+: 14.2;HHSteC: 9.9;hTEC/SVTERT24-B: 5.7;HUVEC TERT2: 10.9;K-562: 6.0;TIME: 6.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 39.4" HPA004094 Approved Supported Nucleoplasm NA NA "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA004094: AB_1859058" "unprognostic (4.48e-2)" "unprognostic (3.24e-2)" "unprognostic (7.77e-3)" "unprognostic (1.36e-2)" "unprognostic (3.51e-1)" "unprognostic (1.53e-1)" "unprognostic (8.37e-2)" "unprognostic (8.35e-3)" "unprognostic (1.97e-2)" "unprognostic (1.04e-1)" "unprognostic (1.97e-1)" "unprognostic (5.74e-2)" "unprognostic (1.69e-6)" "unprognostic (4.10e-3)" "unprognostic (5.41e-2)" "unprognostic (1.63e-4)" "unprognostic (2.61e-2)" 12.2 2.8 7.4 1.5 3.1 0.0 4.5 64.2 12.7 6.5 0.0 4.3 0.5 10.7 2.3 4.5 12.3 5.8 10.2 16.4 3.5 1.1 2.7 3.8 2.7 11.9 5.7 33.3 0.7 0.4 1.1 4.2 12.3 0.9 2.1 1.1 1.0 1.9 18.0 1.6 1.9 17.8 0.2 2.9 2.8 4.3 6.3 1.3 6.8 17.2 1.5 7.0 4.9 3.4 0.0 0.0 6.4 0.0 5.4 1.7 0.0 0.5 14.2 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.0 0.0 4.9 1.6 0.0 0.0 9.9 0.0 0.0 0.5 0.0 5.7 0.0 1.9 10.9 0.0 6.0 0.0 1.3 0.0 1.4 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.4 4.3 0.0 6.5 0.3 0.9 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 3.1 64.2 12.7 16.4 3.5 11.9 5.7 12.3 0.2 6.3 3.4 10.0 0.0 0.6 115.2 0.1 3.6 0.3 0.0 0.6 2.9 0.1 0.3 21.3 0.0 1.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 55.2 0.6 9.8 7.9 0.0 0.0 524.4 0.0 0.1 17.1 1.1 1.5 0.0 24.6 7.1 0.0 0.3 8.4 159.8 0.2 0.0 0.0 1.7 34.0 23.9 0.3 1.8 152.7 0.6 0.1 0.0 689.7 10.0 0.1 0.0 13.5 0.0 0.6 0.0 0.0 0.0 0.7 6.6 22.5 8.1 0.9 2.2 0.1 2.8 0.4 0.2 1.4 0.2 0.4 ZFYVE1 "DFCP1, KIAA1589, PPP1R172, TAFF1, ZNFN2A1" ENSG00000165861 "Zinc finger FYVE-type containing 1" Q9HBF4 14 72969451-73027131 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 45.8;Late spermatids: 108.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002898 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA002898: AB_1080653" "unprognostic (2.19e-1)" "unprognostic (1.50e-1)" "unprognostic (4.65e-2)" "unprognostic (1.23e-1)" "unprognostic (3.47e-1)" "unprognostic (2.40e-2)" "unprognostic (7.42e-3)" "unprognostic (6.82e-2)" "unprognostic (1.05e-2)" "unprognostic (2.40e-2)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" "prognostic favorable (5.07e-12)" "unprognostic (4.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.95e-1)" "unprognostic (7.48e-2)" 11.8 13.5 9.8 5.8 11.3 12.3 9.3 9.8 9.6 8.6 7.4 11.1 9.3 9.1 5.7 13.2 7.2 8.1 9.4 9.4 10.9 12.1 11.2 8.2 7.1 11.3 10.8 9.6 7.7 11.1 6.4 9.4 11.1 7.7 6.6 9.1 8.3 7.1 16.3 13.2 9.1 9.4 10.1 8.2 7.7 16.9 11.2 8.1 12.5 13.7 7.3 9.2 9.3 10.9 8.0 11.3 10.6 10.3 26.9 18.5 7.2 11.5 17.9 12.4 19.5 7.8 6.9 4.2 8.6 14.7 14.6 5.7 7.5 7.1 12.7 16.6 4.2 5.2 5.3 5.5 23.0 1.9 18.7 24.3 18.6 12.2 10.2 18.7 19.7 11.3 4.8 10.8 16.3 9.5 8.3 5.9 5.0 6.4 10.3 11.7 7.4 5.2 11.2 8.3 5.7 9.9 10.4 10.5 12.0 14.6 14.3 7.1 22.0 22.7 9.3 6.4 3.9 15.7 16.9 5.9 12.4 4.2 10.7 2.2 7.0 9.6 6.7 6.3 4.6 3.0 3.4 4.6 6.1 3.0 3.6 4.5 10.9 3.7 5.9 3.5 5.7 5.5 9.8 11.3 9.8 9.6 9.4 10.9 11.3 10.8 11.1 10.1 11.2 10.9 5.6 12.8 5.5 10.1 5.1 6.5 1.8 3.6 8.0 6.2 6.8 4.1 7.8 1.5 3.7 9.2 4.2 3.7 6.8 10.2 1.9 6.4 45.8 6.5 6.3 6.3 7.2 23.1 14.8 5.3 4.4 6.3 7.7 7.0 8.2 9.7 7.1 8.6 5.5 16.8 14.3 7.6 4.1 7.1 3.3 108.9 8.7 7.1 12.4 10.3 6.6 7.6 6.2 13.0 20.6 6.1 9.7 9.1 6.9 3.3 13.1 8.3 3.5 5.4 0.0 5.5 7.6 5.5 3.6 9.0 5.4 9.3 6.4 7.5 4.5 6.2 ZFYVE26 "KIAA0321, SPG15" ENSG00000072121 "Zinc finger FYVE-type containing 26" Q68DK2 14 67727374-67816590 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 50.1;Rod photoreceptor cells: 126.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 4.8" "Lineage enriched" "Detected in single" 11 "dendritic cells: 4.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055500 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA055500: AB_2682837" "unprognostic (3.14e-2)" "unprognostic (1.12e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (1.96e-1)" "unprognostic (1.02e-2)" "prognostic unfavorable (2.84e-6)" "unprognostic (6.87e-2)" "unprognostic (8.18e-2)" "unprognostic (2.97e-2)" "unprognostic (8.29e-3)" "unprognostic (3.71e-2)" "prognostic favorable (1.54e-6)" "unprognostic (1.61e-1)" "unprognostic (1.58e-1)" "unprognostic (6.69e-2)" "unprognostic (5.34e-2)" 5.3 6.4 4.8 5.4 6.3 5.9 5.3 5.8 5.5 5.6 6.8 5.7 4.1 5.7 4.0 5.5 4.5 4.4 5.1 4.5 5.1 4.9 4.4 6.6 7.0 6.4 6.1 6.6 4.9 7.3 5.5 5.9 5.9 4.8 4.7 6.3 4.8 4.6 8.7 7.1 5.8 6.0 5.0 7.3 5.2 2.7 7.8 6.9 5.2 9.6 6.6 5.2 4.8 6.5 12.1 6.9 7.3 7.8 15.2 6.8 10.7 5.8 9.1 13.0 14.9 7.2 7.3 6.7 3.0 7.4 10.8 7.2 10.1 6.9 10.6 6.9 5.6 5.1 8.4 6.7 8.4 3.1 8.3 8.3 9.1 10.1 8.1 6.4 14.6 7.4 7.6 5.3 8.9 9.2 5.1 4.6 3.8 4.8 7.8 4.5 12.1 3.5 5.6 12.2 7.3 4.7 9.0 6.8 8.0 7.1 9.8 4.0 12.9 11.3 9.2 6.9 4.7 4.5 3.3 8.2 9.3 5.6 5.5 0.0 0.2 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.1 0.1 0.0 0.3 0.0 4.8 0.4 0.2 4.8 6.3 5.8 5.5 4.5 5.1 6.4 6.1 5.9 5.0 7.8 6.5 4.4 0.0 9.0 19.9 4.6 2.8 1.8 3.1 6.8 11.6 4.6 3.6 5.8 7.2 4.1 3.7 50.1 2.8 9.6 6.1 0.0 3.9 2.0 4.2 3.7 5.0 3.5 3.8 20.5 2.8 2.4 4.0 5.1 5.2 0.0 6.5 7.1 4.9 9.7 16.8 19.0 3.4 2.0 6.3 6.1 3.1 2.8 8.0 3.6 8.4 7.5 6.9 7.2 16.6 22.1 4.0 6.2 2.2 7.3 2.5 5.0 2.7 4.1 126.3 6.6 7.5 4.0 1.2 1.6 6.9 7.2 4.0 3.8 3.6 3.4 1.9 ZMAT3 "FLJ12296, MGC10613, PAG608, WIG-1, WIG1" ENSG00000172667 "Zinc finger matrin-type 3" Q9HA38 3 178960121-179072215 "Predicted intracellular proteins" "Apoptosis, DNA damage, Growth regulation, Protein transport, Translocation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 105.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HSkMC: 76.0;LHCN-M2: 87.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027569, HPA028671, HPA054356" Enhanced Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "HPA027569: AB_2732438, HPA028671: AB_2672725, HPA054356: AB_2682460" "unprognostic (3.53e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (1.46e-1)" "unprognostic (1.46e-1)" "unprognostic (1.88e-1)" "unprognostic (4.81e-2)" "unprognostic (3.57e-2)" "unprognostic (1.45e-1)" "unprognostic (4.37e-2)" "unprognostic (6.88e-2)" "unprognostic (1.60e-1)" "unprognostic (1.85e-2)" "unprognostic (7.09e-2)" "unprognostic (2.51e-1)" "unprognostic (3.91e-2)" "unprognostic (1.46e-2)" 5.2 7.9 9.9 5.2 10.9 3.4 5.9 4.4 14.5 5.8 3.4 6.3 3.4 5.2 6.2 6.8 5.8 8.9 6.1 12.1 11.0 6.3 12.6 5.9 7.4 10.5 12.1 4.4 4.1 8.8 4.9 5.6 11.9 5.9 8.5 6.1 4.3 7.7 3.1 6.1 3.4 11.2 9.9 6.9 5.1 4.1 12.5 10.2 7.5 4.4 6.4 6.1 3.7 11.7 5.9 4.0 12.8 8.4 57.4 64.2 28.3 23.1 33.9 3.3 4.3 5.1 3.5 24.2 11.1 36.2 5.1 5.4 4.6 24.6 7.6 20.7 7.0 10.7 7.8 16.2 45.7 11.7 16.0 76.0 45.2 8.1 16.7 51.2 48.5 6.8 5.7 3.3 87.7 5.8 9.3 2.1 5.7 8.3 3.3 10.7 11.1 5.2 19.2 11.3 3.0 12.7 7.1 6.4 7.7 23.8 8.0 4.9 53.2 49.9 19.2 8.3 11.0 3.2 2.9 10.2 29.6 1.7 34.9 2.1 0.7 1.7 1.8 0.6 1.0 0.9 1.3 1.4 0.7 1.8 2.2 1.5 0.8 1.6 1.4 0.8 1.0 0.6 9.9 10.9 4.4 14.5 12.1 11.0 10.5 12.1 11.9 9.9 12.5 11.7 11.2 54.5 105.8 38.2 24.6 39.6 10.6 26.1 34.1 19.5 22.2 22.9 21.0 24.3 53.8 35.0 25.0 10.7 25.1 14.0 7.9 16.1 1.1 12.0 15.7 14.6 20.9 14.5 40.7 20.7 2.9 28.2 19.9 12.2 39.8 19.8 17.2 32.1 18.2 62.2 36.7 9.5 30.5 40.2 16.6 2.2 20.2 24.4 51.6 41.2 49.7 15.5 32.0 87.4 18.9 28.6 11.9 29.0 11.1 17.3 14.0 20.2 45.1 11.1 39.5 25.0 23.8 9.5 13.1 25.2 36.7 4.4 29.8 42.8 10.4 11.1 ZMYND8 "PRKCBP1, RACK7" ENSG00000101040 "Zinc finger MYND-type containing 8" Q9ULU4 20 47209214-47356889 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020949 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Golgi apparatus" "HPA020949: AB_1857223" "prognostic unfavorable (2.56e-4)" "unprognostic (5.09e-2)" "unprognostic (5.84e-2)" "unprognostic (3.30e-1)" "unprognostic (2.12e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.62e-4)" "unprognostic (2.10e-1)" "unprognostic (2.60e-1)" "unprognostic (1.50e-1)" "unprognostic (8.64e-2)" "unprognostic (3.62e-1)" "prognostic unfavorable (7.06e-5)" "unprognostic (3.59e-2)" "unprognostic (7.50e-2)" "unprognostic (2.53e-1)" "unprognostic (1.47e-3)" 13.1 32.7 25.4 10.5 21.3 26.0 14.7 26.2 36.2 11.9 47.8 14.1 11.0 9.8 33.3 16.0 15.9 12.3 12.5 35.5 29.5 18.5 10.9 11.1 12.8 30.5 22.9 13.6 12.3 11.6 25.9 11.8 33.0 11.8 14.5 20.1 14.6 14.6 15.3 19.9 16.2 8.7 9.4 18.3 20.0 14.2 25.2 14.6 11.0 11.0 12.8 14.5 14.9 37.3 27.6 17.2 90.5 36.6 15.2 21.3 59.4 21.7 17.8 22.3 22.8 107.7 26.0 26.5 34.4 16.3 27.1 18.7 39.4 96.0 33.3 11.4 14.9 110.4 6.3 95.9 55.4 11.9 55.9 20.9 43.4 24.8 94.1 40.4 61.0 9.5 90.6 17.7 41.0 32.1 4.4 45.4 85.9 20.3 24.3 55.8 15.0 22.9 30.4 49.6 38.0 14.3 10.3 32.4 44.4 70.3 17.0 22.6 143.6 23.9 16.6 23.3 20.2 12.5 25.2 23.2 80.8 18.3 80.3 34.8 7.4 10.4 8.7 7.5 8.7 15.3 8.8 9.0 4.7 18.3 11.4 11.8 19.8 16.3 6.8 16.5 9.3 4.3 25.4 21.3 26.2 36.2 35.5 29.5 30.5 22.9 33.0 9.4 25.2 37.3 48.2 44.8 78.5 94.0 36.6 8.8 32.2 44.6 15.9 108.1 29.3 20.7 23.7 28.6 74.3 90.1 160.6 23.1 36.2 64.0 15.6 36.5 13.6 111.3 29.8 31.7 56.3 112.9 153.8 28.7 42.0 24.2 41.8 124.4 32.2 44.8 30.7 16.1 21.9 85.8 113.5 49.2 42.7 48.8 12.8 21.9 27.7 31.8 10.6 49.6 25.0 24.4 40.2 89.0 138.7 47.1 42.3 26.7 29.7 23.9 56.8 12.0 82.3 50.0 32.9 33.4 27.5 6.3 29.9 19.2 8.4 66.5 34.2 39.3 32.1 24.2 ZNF185 SCELL ENSG00000147394 "Zinc finger protein 185 with LIM domain" O15231 X 152914442-152973480 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 328.7;esophagus: 326.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 32.2;Pancreatic endocrine cells: 72.0;Squamous epithelial cells: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.8" "Group enriched" "Detected in many" 5 "granulocytes: 51.8;monocytes: 27.4" "Cell line enhanced" "Detected in many" "A-431: 124.4;EFO-21: 139.9;HBEC3-KT: 100.0;PC-3: 87.7;TIME: 236.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000400, HPA016438" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Actin filaments, Focal adhesion sites" "HPA000400: AB_1080685, HPA016438: AB_1859109" "unprognostic (1.34e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" "unprognostic (9.75e-3)" "unprognostic (2.69e-1)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (7.94e-2)" "unprognostic (6.28e-2)" "prognostic unfavorable (3.30e-5)" "unprognostic (5.18e-2)" "unprognostic (8.12e-2)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" 5.2 11.6 4.0 5.6 4.2 8.7 12.2 4.8 3.7 69.5 10.9 4.5 1.8 21.8 328.7 326.7 16.4 6.7 1.8 3.2 3.9 11.0 2.1 12.1 4.5 3.5 3.8 6.1 4.3 3.7 8.4 24.9 3.5 24.5 4.2 3.4 44.8 144.1 2.9 53.7 2.6 10.3 4.2 4.5 7.4 3.4 4.3 3.6 21.3 2.9 41.0 11.6 117.5 3.9 124.4 25.9 2.4 1.6 3.0 4.0 5.5 6.0 0.4 14.8 2.2 0.9 36.7 1.6 139.9 9.0 1.4 17.3 3.7 100.0 60.1 1.5 2.4 7.9 9.8 4.1 7.0 0.5 0.6 2.9 70.2 1.6 57.0 14.6 76.5 1.6 0.5 1.1 0.4 29.1 0.5 0.7 1.9 31.4 87.7 0.5 0.4 0.9 7.7 11.5 1.0 8.2 0.2 22.7 3.6 23.3 23.3 2.7 236.2 0.8 50.5 3.0 4.5 1.2 1.0 1.1 1.6 8.9 1.7 51.8 27.4 11.4 1.0 24.4 0.6 0.7 0.7 1.2 7.4 0.6 1.1 0.7 18.5 0.5 21.1 4.9 1.0 20.7 4.0 4.2 4.8 3.7 3.2 3.9 3.5 3.8 3.5 4.2 4.3 3.9 1.1 12.8 2.6 1.3 0.7 9.2 6.2 5.7 4.6 0.5 5.7 7.6 0.9 1.5 9.4 9.2 2.1 3.8 1.7 1.0 0.0 8.6 0.6 14.1 4.2 1.1 0.0 0.0 1.0 3.0 5.0 2.2 2.6 32.2 1.3 3.9 1.4 0.1 9.4 0.0 1.7 2.5 2.0 11.3 4.0 0.3 1.2 9.5 3.6 0.0 14.4 4.0 0.0 1.0 1.4 72.0 0.3 1.2 0.1 7.6 0.3 1.2 6.9 0.3 0.0 0.5 1.9 4.2 5.8 69.7 21.2 0.7 0.8 0.4 2.4 21.3 ZNF277 "NRIF4, ZNF277P" ENSG00000198839 "Zinc finger protein 277" Q9NRM2 7 112206695-112343934 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027307 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 32: Non-specific - Translation" Nucleoplasm "Plasma membrane" "HPA027307: AB_1859164" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (1.07e-1)" "unprognostic (3.95e-2)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (1.43e-1)" "unprognostic (4.18e-2)" "unprognostic (4.60e-2)" "unprognostic (7.61e-2)" "unprognostic (1.88e-2)" "unprognostic (2.85e-1)" "prognostic favorable (9.47e-4)" "unprognostic (1.05e-1)" "unprognostic (2.64e-2)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" 7.5 6.8 3.9 5.4 4.9 6.1 8.9 4.2 7.2 6.1 3.8 7.1 5.9 6.7 3.1 7.1 6.0 6.4 8.0 4.5 3.7 9.5 11.6 7.0 6.8 4.7 3.8 7.1 11.3 7.1 4.6 4.6 4.6 5.6 6.9 4.5 7.1 4.4 6.5 8.3 5.6 6.0 3.8 5.8 7.8 5.4 4.7 7.9 9.4 3.4 6.3 8.2 7.0 7.1 7.6 4.5 7.5 9.3 10.2 28.1 5.6 7.4 7.9 3.5 6.3 6.8 6.8 12.6 13.3 6.1 7.2 5.0 5.7 7.3 9.4 10.2 3.6 6.6 6.1 5.8 6.3 12.1 5.2 17.1 10.8 8.6 5.7 11.1 10.7 13.2 7.9 13.3 6.4 8.8 15.2 20.6 5.1 6.5 5.0 7.4 8.2 11.4 9.5 5.6 5.3 13.8 9.7 12.0 11.9 8.1 3.4 10.2 14.9 5.4 3.1 12.0 4.8 11.5 14.6 14.8 3.9 11.5 6.6 9.3 4.6 6.4 5.7 8.1 8.5 8.7 8.0 8.2 3.7 9.6 9.6 8.1 6.6 7.4 7.2 5.9 9.4 3.7 3.9 4.9 4.2 7.2 4.5 3.7 4.7 3.8 4.6 3.8 4.7 7.1 13.0 38.5 24.6 77.1 25.7 20.6 18.2 35.7 26.2 10.0 19.0 17.5 12.8 27.1 24.1 5.5 2.1 12.3 19.6 12.4 27.4 25.9 46.4 13.6 15.6 17.9 18.5 11.1 51.9 31.0 18.3 15.7 12.8 16.3 7.6 21.4 16.4 19.2 21.7 32.0 43.4 22.5 34.6 46.9 34.8 8.6 17.1 29.1 12.4 43.1 50.6 6.6 37.0 47.7 70.5 24.6 22.9 25.2 13.2 17.5 27.0 34.5 12.7 12.0 19.7 17.1 23.7 32.8 10.4 19.1 24.3 13.8 25.8 28.1 22.4 21.5 ZNF366 FLJ39796 ENSG00000178175 "Zinc finger protein 366" Q8N895 5 72439903-72507410 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 19.0;Cone photoreceptor cells: 31.3;Endothelial cells: 18.3;Langerhans cells: 9.3;Microglial cells: 54.4;monocytes: 14.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "myeloid DC: 10.4" "Lineage enriched" "Detected in many" 9 "dendritic cells: 10.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 1.3;TIME: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023128, HPA023526, HPA074074" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA023128: AB_1859223, HPA023526: AB_1859224, HPA074074: " "unprognostic (3.49e-1)" "unprognostic (8.44e-2)" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "unprognostic (6.17e-2)" "unprognostic (1.95e-3)" "unprognostic (9.25e-2)" "unprognostic (6.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (1.88e-3)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (6.29e-2)" 5.8 0.8 6.1 3.4 5.0 0.1 3.2 4.5 5.6 2.8 2.4 1.4 1.5 3.1 0.7 1.8 2.4 2.3 3.8 4.1 4.6 2.1 1.0 2.6 5.0 5.8 5.5 0.8 0.7 1.1 0.4 8.9 6.0 0.9 1.5 0.5 0.8 1.5 5.0 2.2 1.9 3.9 4.1 6.4 1.4 0.5 7.1 3.1 2.2 5.6 4.0 1.7 1.0 4.5 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.5 6.1 5.0 4.5 5.6 4.1 4.6 5.8 5.5 6.0 4.1 7.1 4.5 19.0 0.0 0.6 0.0 0.1 0.5 0.4 0.0 0.6 0.4 0.1 0.3 1.6 0.0 0.6 0.0 31.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.8 0.4 0.5 0.0 0.3 0.0 0.0 4.6 9.3 0.5 0.3 2.4 0.0 54.4 14.5 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 1.2 0.7 0.0 0.0 0.2 0.3 0.1 0.3 0.1 0.0 0.0 ZYX ENSG00000159840 Zyxin Q15942 7 143381295-143391111 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 596.6" "Cell type enhanced" "Detected in many" "Macrophages: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 163.3" "Group enriched" "Detected in all" 4 "dendritic cells: 58.4;granulocytes: 163.3;monocytes: 83.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004835, CAB009321, HPA073497, CAB075747" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 180000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites" "Plasma membrane, Actin filaments" "CAB009321: AB_2221290, CAB075747: AB_2665753, HPA004835: AB_1080771, HPA073497: AB_2686611" "unprognostic (1.96e-2)" "unprognostic (5.35e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (2.21e-3)" "unprognostic (1.66e-3)" "unprognostic (2.60e-1)" "unprognostic (4.22e-1)" "unprognostic (1.98e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (7.92e-5)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (1.95e-1)" "unprognostic (6.72e-2)" 211.5 75.4 21.6 82.5 24.3 106.3 191.0 24.4 33.5 275.7 24.8 382.6 28.1 596.6 16.5 136.7 294.9 57.0 152.0 21.9 21.9 99.4 89.9 316.8 53.9 27.5 24.7 168.7 78.5 84.3 52.4 38.4 27.5 171.9 20.2 5.2 108.1 75.3 113.3 130.7 148.7 127.7 23.8 213.6 154.0 98.9 28.8 27.6 89.0 19.1 31.1 301.6 185.9 26.8 73.9 39.3 50.6 70.5 93.9 208.2 63.4 152.1 158.9 146.5 122.7 135.4 42.6 4.6 57.5 168.5 84.1 55.8 31.7 138.0 67.8 81.6 18.7 105.9 45.7 46.9 163.8 86.4 162.6 222.9 60.5 160.1 54.0 90.5 187.9 9.1 28.0 42.8 159.6 73.4 1.3 165.9 110.0 25.4 273.1 16.3 28.0 6.4 112.2 34.6 2.8 39.5 112.3 99.2 57.0 45.9 12.1 80.5 343.7 176.5 74.1 187.9 152.4 15.6 20.4 11.7 154.6 87.4 119.8 18.9 70.8 48.2 20.2 70.4 16.2 3.1 19.4 23.3 58.4 2.0 11.7 13.8 163.3 14.7 83.6 14.5 19.1 44.1 21.6 24.3 24.4 33.5 21.9 21.9 27.5 24.7 27.5 23.8 28.8 26.8 51.6 6.4 6.4 8.1 26.7 33.8 174.0 78.4 26.7 3.7 40.2 85.3 11.6 25.8 45.4 35.0 0.0 40.6 51.7 40.1 7.9 100.3 1.5 23.4 172.6 58.2 38.2 19.3 36.9 94.1 95.8 66.6 44.9 42.0 36.8 13.7 55.3 32.0 164.6 0.0 18.3 26.7 24.4 195.7 95.1 6.8 28.6 207.1 14.2 7.5 171.9 15.1 40.2 7.5 5.2 169.8 48.2 55.3 20.3 61.3 19.8 19.6 9.9 3.0 85.5 48.7 103.9 7.3 9.9 46.3 20.2 28.0 91.9 8.8 28.6 106.4