Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABHD13 "bA153I24.2, BEM46L1, C13orf6, FLJ14906" ENSG00000139826 "Abhydrolase domain containing 13" Q7L211 13 108218392-108234243 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032143, HPA032144" Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 43: THP-1 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" Cytosol "HPA032143: AB_2674178, HPA032144: AB_10602304" "unprognostic (2.69e-1)" "unprognostic (2.81e-1)" "unprognostic (1.36e-2)" "unprognostic (2.91e-2)" "unprognostic (8.36e-2)" "unprognostic (1.48e-2)" "unprognostic (1.99e-1)" "unprognostic (2.63e-1)" "unprognostic (8.75e-2)" "unprognostic (1.79e-1)" "unprognostic (1.92e-1)" "unprognostic (6.21e-2)" "unprognostic (1.14e-1)" "unprognostic (2.73e-2)" "unprognostic (1.61e-1)" "unprognostic (1.14e-1)" "unprognostic (5.62e-2)" 7.0 5.3 3.7 7.0 4.0 16.3 7.3 5.9 5.3 6.2 7.0 6.5 7.0 6.3 10.2 5.6 4.3 6.4 4.3 4.1 3.2 6.1 10.4 6.9 8.3 3.3 3.3 5.2 4.7 5.7 3.8 8.4 3.2 6.2 7.3 6.4 4.6 5.6 4.2 4.3 7.4 6.8 3.2 7.8 6.8 3.8 3.4 9.3 7.6 6.4 7.1 7.5 4.3 3.9 9.8 4.0 10.5 5.9 8.0 9.5 5.1 9.5 9.5 8.2 9.7 6.2 9.1 8.2 9.7 7.4 8.1 8.8 7.9 11.0 13.0 11.1 6.9 10.1 5.7 6.1 8.0 21.1 12.0 9.8 10.3 6.4 8.3 7.7 9.8 11.2 5.5 4.5 8.5 4.1 10.3 8.8 5.0 14.5 4.7 8.7 7.5 4.8 11.5 8.7 7.9 9.9 5.0 8.3 10.6 9.3 7.7 19.3 10.2 5.8 6.0 6.8 6.5 8.8 7.4 9.0 13.7 13.0 10.7 7.7 8.2 16.0 5.9 7.6 8.8 6.8 8.0 7.2 7.2 6.0 7.6 6.3 9.0 9.5 7.2 5.3 8.4 8.6 3.7 4.0 5.9 5.3 4.1 3.2 3.3 3.3 3.2 3.2 3.4 3.9 17.6 22.4 16.6 8.1 24.5 44.4 21.4 33.3 15.9 12.8 16.8 10.8 7.2 27.1 22.2 11.0 0.0 20.9 23.7 14.7 9.8 19.1 24.8 12.3 13.4 18.2 30.5 16.2 21.4 21.0 15.4 19.9 19.9 14.4 14.0 9.5 19.6 29.5 19.5 18.5 17.4 11.6 44.7 21.5 40.1 18.2 15.5 24.6 26.6 15.0 25.8 12.6 19.6 16.1 15.2 20.8 14.3 17.3 10.2 20.7 16.4 11.5 18.4 12.2 19.7 15.1 18.2 22.9 12.3 21.1 51.1 21.3 28.4 12.5 12.1 26.3 AC008763.3 ENSG00000269711 "Novel protein" 19 7678501-7682854 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "bone marrow: 22.6;intestine: 7.7;lung: 18.3;lymphoid tissue: 12.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.3;Club cells: 3.7;Fibroblasts: 1.3;granulocytes: 2.5;Macrophages: 1.3;Respiratory ciliated cells: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "classical monocyte: 202.7;neutrophil: 90.1" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "EFO-21: 12.8;HMC-1: 20.9;NB-4: 12.4;THP-1: 33.2;U-937: 24.6" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" 2.3 0.8 0.3 4.6 0.4 22.6 0.6 0.2 0.5 0.2 0.1 0.5 7.7 1.1 0.0 0.4 1.8 1.5 1.4 0.2 0.3 0.7 1.8 18.3 0.0 1.0 0.7 0.1 0.7 0.0 0.3 1.6 0.5 0.5 0.0 0.0 1.2 0.0 0.7 0.9 1.4 0.1 0.2 12.2 0.9 0.6 0.3 0.0 0.6 0.0 0.0 1.2 0.4 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 4.5 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 202.7 1.3 0.2 18.1 0.0 0.0 0.5 0.1 42.9 0.0 0.0 1.4 90.1 0.7 1.7 1.8 0.8 112.3 0.3 0.4 0.2 0.5 0.2 0.3 1.0 0.7 0.5 0.2 0.3 0.1 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 AC073896.1 ENSG00000144785 "Novel protein" 12 56285916-56316059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 18.8;salivary gland: 19.4" "Cell type enhanced" "Detected in single" "Club cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA038466, HPA068007" Uncertain Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 4: Stomach - Digestion" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Centriolar satellite" "HPA038466: AB_10672646, HPA068007: " "unprognostic (3.07e-2)" "unprognostic (9.89e-3)" "unprognostic (8.23e-2)" "unprognostic (3.45e-2)" "unprognostic (8.20e-3)" "unprognostic (1.63e-1)" "unprognostic (2.13e-1)" "unprognostic (1.38e-1)" "unprognostic (3.74e-3)" "unprognostic (2.83e-1)" "unprognostic (1.04e-1)" "unprognostic (9.26e-4)" "unprognostic (2.22e-1)" "unprognostic (3.01e-1)" "unprognostic (1.93e-1)" 7.0 5.7 1.5 3.5 1.5 5.1 3.9 1.5 5.3 1.7 2.6 8.9 9.8 1.2 0.3 3.0 3.3 5.9 1.4 1.7 1.2 3.0 4.7 1.8 2.2 1.6 1.4 3.7 18.8 3.7 0.3 4.4 1.6 2.5 0.3 0.7 19.4 6.6 1.5 1.0 5.6 0.9 1.3 4.2 7.0 2.0 1.6 3.3 3.3 1.4 0.9 2.6 0.3 2.2 22.0 38.1 5.4 23.4 17.4 12.6 37.7 42.5 42.1 33.2 23.4 43.2 22.7 15.8 61.9 17.7 18.8 49.0 9.9 15.3 3.8 30.6 18.4 0.8 22.8 42.6 37.6 15.5 45.4 24.5 23.3 18.3 1.1 19.8 29.0 43.8 19.2 18.5 5.1 36.9 11.0 24.7 37.5 19.1 97.7 50.3 21.2 29.2 0.3 3.4 30.6 29.1 26.1 25.8 26.9 0.6 20.9 84.8 20.6 30.1 15.6 18.8 37.4 29.4 62.0 17.1 41.4 27.0 41.3 31.5 41.3 19.4 40.8 36.4 41.6 65.1 35.5 43.2 50.3 51.9 40.9 38.7 6.9 41.7 22.1 59.5 39.6 70.1 1.5 1.5 1.5 5.3 1.7 1.2 1.6 1.4 1.6 1.3 1.6 2.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 AC090527.2 ENSG00000260170 "Novel protein" 15 45587351-45676314 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "neutrophil: 6.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HBEC3-KT: 1.3;THP-1: 1.1" HPA041589 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA041589: AB_2677565" "unprognostic (5.93e-2)" "unprognostic (1.18e-1)" "unprognostic (2.03e-2)" "unprognostic (1.54e-1)" 0.1 0.0 0.1 0.0 0.2 0.4 0.1 0.0 0.2 0.0 0.2 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 1.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.7 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.3 0.2 2.2 1.7 0.9 0.8 0.8 1.0 0.7 0.7 0.3 0.0 1.3 1.6 0.4 6.2 0.0 0.9 0.5 1.2 0.4 0.1 0.2 0.0 0.2 0.2 0.1 0.1 0.2 0.2 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AFG1L "AFG1, LACE1" ENSG00000135537 "AFG1 like ATPase" Q8WV93 6 108294991-108526796 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 6.4;Distal tubular cells: 9.8;Hofbauer cells: 5.7;Proximal tubular cells: 6.3;Respiratory ciliated cells: 5.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030154, HPA030155, HPA030659" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA030154: AB_10600769, HPA030155: AB_10601232, HPA030659: AB_10602415" "unprognostic (9.76e-5)" "unprognostic (1.72e-1)" "unprognostic (1.68e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-1)" "unprognostic (7.04e-2)" "unprognostic (2.57e-1)" "unprognostic (5.53e-2)" "unprognostic (2.35e-3)" "unprognostic (1.48e-1)" "unprognostic (2.73e-2)" "unprognostic (9.61e-2)" "unprognostic (8.40e-8)" "unprognostic (2.03e-2)" "unprognostic (2.03e-1)" "unprognostic (1.41e-1)" "unprognostic (1.23e-1)" 1.8 2.1 2.2 1.3 2.7 2.1 2.2 2.0 3.3 1.7 2.7 2.6 4.2 1.5 1.9 1.6 2.2 1.5 4.6 1.7 1.9 5.0 3.7 1.7 1.8 1.8 2.0 1.7 2.1 5.4 1.5 2.2 2.0 1.6 3.1 3.1 1.8 1.7 3.7 1.2 3.0 1.7 1.7 2.0 2.8 10.7 2.7 2.3 3.0 4.0 2.1 1.7 1.1 3.2 2.7 1.4 3.4 6.1 3.5 5.1 3.3 3.0 4.4 4.8 4.7 5.7 3.3 4.8 3.8 4.7 5.8 1.5 4.4 4.5 5.4 2.8 2.6 5.7 1.8 6.6 3.5 5.3 2.7 4.7 3.6 3.6 5.8 3.1 2.6 3.5 5.9 2.2 4.5 2.6 0.9 4.8 2.2 4.6 2.8 3.3 4.6 2.8 6.1 2.9 3.7 3.2 2.4 3.5 6.4 4.5 2.8 9.8 3.2 2.9 0.7 2.6 3.4 1.5 2.6 3.7 3.6 6.0 4.5 0.0 1.6 2.8 1.0 1.2 1.3 2.5 1.5 1.9 1.4 3.4 2.1 1.4 0.4 2.4 4.3 1.6 2.3 0.7 2.2 2.7 2.0 3.3 1.7 1.9 1.8 2.0 2.0 1.7 2.7 3.2 2.4 0.0 4.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 2.2 0.0 0.0 5.0 3.7 0.0 6.4 1.1 0.0 9.8 3.1 0.0 2.6 2.6 2.2 0.0 0.0 0.0 3.8 4.6 1.2 0.0 1.8 2.5 5.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.4 0.0 0.0 6.3 5.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.2 0.9 4.5 0.0 0.0 AGO4 "EIF2C4, FLJ20033, hAGO4, KIAA1567" ENSG00000134698 "Argonaute RISC component 4" Q9HCK5 1 35808016-35857890 "Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 60.6;Inhibitory neurons: 72.0;Microglial cells: 63.7;Oligodendrocyte precursor cells: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "THP-1: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012179, HPA067849" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Cytoplasmic bodies" Cytosol "CAB012179: , HPA067849: " "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (5.01e-2)" "unprognostic (1.76e-1)" "prognostic favorable (5.70e-5)" "unprognostic (3.92e-3)" "unprognostic (3.99e-3)" "unprognostic (2.32e-2)" "unprognostic (9.28e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-3)" "unprognostic (4.91e-3)" "unprognostic (4.96e-2)" "unprognostic (2.58e-1)" "unprognostic (3.96e-1)" "unprognostic (1.58e-2)" 8.8 4.9 7.2 8.8 7.1 20.4 7.7 8.6 7.9 8.4 8.6 9.6 4.7 8.9 6.6 7.3 7.2 6.2 9.9 6.8 6.8 5.0 7.5 11.4 7.0 7.4 7.1 7.0 8.6 6.5 5.8 8.9 7.4 8.1 6.4 18.1 8.4 6.1 13.3 20.1 7.8 9.8 6.8 14.2 9.7 7.3 7.3 7.3 5.5 11.8 6.8 8.2 8.5 7.6 6.0 1.5 11.3 6.5 5.8 6.6 5.7 4.5 4.4 4.6 5.3 0.8 9.0 9.6 6.0 6.6 4.7 2.4 4.9 3.6 4.3 10.7 4.5 4.9 4.2 2.8 5.5 5.6 7.2 4.3 7.6 2.5 3.8 8.8 7.9 11.5 3.7 3.7 6.2 0.9 9.1 6.2 3.7 3.8 2.7 9.0 10.1 1.2 4.5 7.4 5.0 7.3 4.1 3.7 12.7 9.6 3.0 24.6 9.5 3.5 1.7 3.6 3.4 5.4 1.8 1.4 4.3 7.0 3.2 1.3 2.7 3.0 0.8 1.5 1.4 0.6 0.7 1.1 2.0 0.4 0.3 0.4 7.5 0.6 1.4 0.4 0.2 0.8 7.2 7.1 8.6 7.9 6.8 6.8 7.4 7.1 7.4 6.8 7.3 7.6 16.4 19.2 21.7 54.9 6.7 9.8 4.7 5.4 9.6 28.2 8.5 7.1 21.8 12.8 9.2 11.0 22.9 4.2 17.9 5.5 1.9 5.6 2.0 12.7 9.4 11.6 12.6 5.0 60.6 5.6 4.7 7.2 10.7 10.9 2.5 11.4 22.1 11.5 13.5 6.7 72.0 8.4 2.0 42.3 10.0 1.6 5.0 28.9 3.6 63.7 33.6 6.5 6.2 87.4 54.8 14.4 11.7 5.7 4.3 9.0 10.0 1.5 10.3 32.2 19.7 6.8 8.5 11.3 1.6 5.9 12.8 4.1 10.3 3.6 5.7 6.7 AL136295.1 ENSG00000254692 "Novel protein" 14 24189157-24213473 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 6.4;granulocytes: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SiHa: 8.1" HPA059249 Approved Approved "Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" "HPA059249: AB_2683959" "unprognostic (3.45e-2)" 1.7 3.0 0.6 2.1 0.7 2.0 0.8 0.7 1.5 1.2 0.5 1.3 2.5 1.0 0.2 0.8 1.1 0.4 1.7 0.6 0.8 1.7 0.8 1.1 1.4 0.8 0.6 0.9 1.4 0.5 0.5 0.7 0.7 0.8 0.9 1.3 0.8 0.6 1.9 1.3 2.2 0.6 0.5 0.8 1.3 1.0 0.8 1.6 0.8 0.0 0.4 0.8 0.7 0.7 1.5 1.4 2.4 0.9 2.2 1.3 1.9 1.4 2.0 1.0 2.2 1.0 5.1 1.5 0.2 1.8 2.9 1.5 1.5 0.8 3.2 2.4 0.0 0.9 0.8 1.2 0.4 4.3 2.5 0.5 0.8 1.2 0.0 3.5 0.7 1.3 0.1 4.3 1.7 1.2 1.1 0.0 2.1 0.7 0.0 1.7 1.9 0.0 1.9 1.1 0.2 1.0 8.1 2.7 3.4 2.8 2.0 3.4 4.4 0.2 1.0 1.3 2.1 3.4 2.6 3.6 0.5 0.9 0.8 0.0 0.1 0.5 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.3 0.1 0.6 0.7 0.7 1.5 0.6 0.8 0.8 0.6 0.7 0.5 0.8 0.7 0.0 6.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 AL359092.3 ENSG00000288570 "Novel protein" 9 130713626-130713724 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.6;stomach 1: 1.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 27 "cerebral cortex: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Karpas-707: 1.1;SK-MEL-30: 1.4;T-47d: 1.1;THP-1: 2.9" NA NA "Cluster 43: THP-1 - Innate immune response" 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 311.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" NA NA 2000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" 119.2 105.5 49.6 29.8 51.0 24.8 76.8 49.3 60.3 51.5 62.5 45.7 54.8 38.6 93.4 105.6 50.2 32.0 48.2 47.4 57.5 142.4 206.5 38.5 40.3 50.5 52.1 53.6 44.0 81.9 39.9 38.0 51.4 65.3 50.6 46.4 104.1 45.6 93.6 54.7 48.6 42.0 50.7 37.9 39.5 63.4 49.3 39.0 123.0 56.4 60.1 39.4 43.9 55.6 55.7 53.5 48.7 44.1 152.1 132.8 40.7 71.9 101.5 70.8 61.0 33.4 40.7 0.1 67.1 64.8 34.9 42.8 40.0 70.3 83.0 25.9 50.6 35.3 34.7 36.5 78.2 56.0 36.1 86.0 34.8 75.2 62.5 97.8 62.2 45.9 56.9 48.4 111.7 33.4 37.6 57.6 71.3 145.1 64.7 31.7 62.0 74.3 92.5 52.0 57.7 39.8 51.4 57.1 67.4 65.6 108.8 84.0 61.9 42.5 41.5 52.4 37.1 44.7 62.5 54.8 47.9 52.6 41.7 61.8 35.2 50.9 45.5 37.7 48.8 49.9 43.8 49.6 34.5 46.8 43.8 50.4 51.3 43.0 45.3 21.6 69.8 45.6 49.6 51.0 49.3 60.3 47.4 57.5 50.5 52.1 51.4 50.7 49.3 55.6 56.2 16.0 47.6 12.7 43.3 32.6 43.3 43.8 68.3 25.0 83.0 54.6 46.5 55.8 36.8 51.5 22.9 48.5 39.3 43.9 97.8 42.9 45.4 27.7 39.1 49.4 55.8 28.2 5.6 37.0 76.4 60.6 36.2 20.4 38.0 60.9 59.3 158.8 61.9 13.5 8.3 56.9 32.6 59.1 24.9 39.8 95.4 43.8 56.9 6.5 34.6 311.5 39.1 12.1 12.2 32.2 33.1 115.5 34.8 39.6 80.3 204.4 59.4 28.9 26.3 32.5 40.1 85.6 49.9 123.8 51.9 38.2 43.7 148.4 63.6 28.3 ANKRD10 FLJ20093 ENSG00000088448 "Ankyrin repeat domain 10" Q9NXR5 13 110878540-110915069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034211, HPA038878, HPA038879" Uncertain Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB034211: AB_2058024, HPA038878: AB_2676252, HPA038879: AB_2676253" "unprognostic (3.29e-2)" "unprognostic (2.38e-1)" "unprognostic (9.26e-2)" "unprognostic (1.06e-1)" "unprognostic (2.89e-3)" "unprognostic (2.49e-1)" "unprognostic (4.97e-3)" "unprognostic (9.60e-2)" "unprognostic (1.16e-1)" "unprognostic (2.61e-1)" "unprognostic (1.16e-1)" "unprognostic (2.92e-2)" "prognostic unfavorable (1.25e-6)" "unprognostic (1.95e-1)" "unprognostic (2.68e-1)" "unprognostic (8.32e-2)" "prognostic favorable (6.41e-6)" 78.2 60.3 61.9 42.2 69.8 88.7 75.6 65.9 85.2 109.1 71.4 97.2 43.8 87.4 89.9 37.6 90.7 53.5 74.3 62.6 68.8 93.9 84.1 91.7 63.3 72.5 65.8 99.6 94.9 25.5 97.5 36.4 75.5 108.1 50.2 77.6 70.3 42.4 176.6 48.9 88.1 49.0 66.3 138.9 75.0 40.8 67.7 52.4 82.1 73.4 50.4 79.2 68.3 80.1 36.1 29.6 66.7 56.2 50.2 48.4 29.6 24.0 50.0 23.5 28.9 31.0 68.8 49.5 51.1 18.2 38.2 81.1 29.2 22.6 31.7 119.1 43.2 59.0 73.3 64.9 20.0 85.9 49.4 46.2 33.7 16.5 24.4 49.1 32.1 48.8 26.4 33.1 64.2 10.8 49.9 95.3 37.0 79.1 18.3 76.0 24.5 49.6 64.9 39.4 53.2 39.7 18.2 31.7 39.9 49.7 22.7 108.0 28.0 27.6 23.0 13.7 24.7 40.8 46.9 28.9 51.7 41.5 44.2 39.0 25.8 22.7 30.4 21.1 26.3 42.9 29.2 25.3 33.8 44.7 30.9 33.7 16.1 31.8 22.3 31.5 39.9 26.8 61.9 69.8 65.9 85.2 62.6 68.8 72.5 65.8 75.5 66.3 67.7 80.1 77.6 16.0 65.4 83.6 69.3 94.3 39.0 25.9 129.1 33.3 72.2 55.0 32.0 45.8 45.3 38.6 54.2 45.1 54.4 43.4 19.6 52.1 8.5 59.0 79.2 83.3 41.9 30.3 118.7 49.2 51.8 78.3 51.5 105.4 30.4 65.3 40.7 48.8 46.6 32.0 105.8 55.2 57.0 46.5 99.7 7.3 39.1 60.4 72.9 145.2 44.7 28.6 35.0 158.3 203.6 38.7 46.2 51.6 58.5 62.5 40.9 45.1 40.8 55.4 52.6 105.6 88.8 28.0 23.6 44.3 77.7 38.9 58.9 44.9 59.6 53.2 ANKRD18A "FLJ35740, KIAA2015" ENSG00000180071 "Ankyrin repeat domain 18A" Q8IVF6 9 38571358-38620596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 18.2;brain: 21.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.3;Excitatory neurons: 24.8;Inhibitory neurons: 26.8;Oligodendrocytes: 118.1;Rod photoreceptor cells: 31.2;Spermatocytes: 53.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 17.9" "HPA046346, HPA046695, HPA049923, HPA051288" Uncertain Uncertain "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli, Nucleoli rim" Cytosol "HPA046346: AB_2679631, HPA046695: , HPA049923: AB_2680954, HPA051288: AB_2681421" "unprognostic (4.02e-2)" "unprognostic (1.07e-1)" "unprognostic (1.42e-3)" "unprognostic (1.69e-2)" "unprognostic (2.05e-1)" "unprognostic (2.38e-2)" "unprognostic (1.26e-1)" "unprognostic (2.37e-1)" "unprognostic (4.34e-1)" "unprognostic (1.15e-1)" "unprognostic (1.92e-2)" "unprognostic (1.94e-5)" "unprognostic (2.31e-2)" "unprognostic (1.63e-2)" "unprognostic (1.58e-2)" "unprognostic (7.03e-2)" "unprognostic (2.14e-1)" 0.0 0.1 3.0 0.3 9.1 18.2 0.4 3.6 3.7 0.4 0.0 0.5 0.3 0.2 0.2 0.8 0.5 0.4 0.6 3.1 5.1 0.9 0.7 0.3 0.2 12.6 6.0 0.0 2.2 0.6 1.0 0.1 14.3 0.9 0.7 5.0 0.4 0.1 0.0 1.3 0.7 0.2 5.1 0.1 1.0 7.2 8.4 0.3 2.2 0.0 0.1 0.2 0.4 21.9 4.8 3.7 3.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 1.9 0.0 0.0 0.9 3.5 3.4 0.0 0.0 5.2 0.0 5.6 2.9 0.0 17.9 0.5 0.0 2.3 0.0 3.1 1.7 0.0 7.2 1.7 0.4 0.3 4.6 0.1 0.9 3.7 6.2 2.1 0.0 6.5 6.8 2.1 2.0 1.5 3.0 2.4 0.5 0.2 7.1 2.6 8.3 4.5 0.0 1.3 0.1 0.0 0.3 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 3.0 9.1 3.6 3.7 3.1 5.1 12.6 6.0 14.3 5.1 8.4 21.9 0.1 0.0 1.5 1.0 0.1 0.6 2.0 1.5 3.4 3.8 2.3 2.4 9.4 1.5 3.7 1.8 2.1 0.0 0.1 0.8 1.9 5.4 8.0 33.3 1.7 0.2 4.2 0.0 24.8 2.4 0.9 0.2 7.7 19.2 0.0 14.7 0.0 0.5 0.1 0.0 26.8 3.3 2.0 0.0 0.3 2.2 0.6 0.2 0.0 1.0 0.4 9.2 0.0 18.1 118.1 3.9 2.6 0.4 0.1 1.9 1.6 0.3 11.0 31.2 0.0 0.0 0.3 53.5 4.3 3.8 1.7 0.0 1.4 0.3 2.3 1.4 AOC1 "ABP, ABP1, DAO" ENSG00000002726 "Amine oxidase copper containing 1" P19801 7 150824627-150861504 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 227.2;kidney: 136.5;placenta: 496.7" "Cell type enhanced" "Detected in many" "Collecting duct cells: 272.2;Distal enterocytes: 517.5;Paneth cells: 532.1;Proximal enterocytes: 957.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 61.3;endometrial cancer: 39.1;pancreatic cancer: 26.9;renal cancer: 69.4;stomach cancer: 43.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 12 "eosinophil: 31.2" "Lineage enriched" "Detected in many" 22 "granulocytes: 31.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 20.5;HaCaT: 6.2;NB-4: 6.4;RPMI-8226: 7.7;THP-1: 27.1" "Low region specificity" "Detected in many" "HPA031032, HPA031033" Approved "Secreted in other tissues" NA NA 2500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 43: THP-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "HPA031032: AB_10670150, HPA031033: AB_10669670" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.84e-2)" "unprognostic (6.31e-3)" "unprognostic (8.31e-3)" "unprognostic (9.07e-3)" "unprognostic (6.42e-2)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (3.11e-1)" "prognostic favorable (1.71e-4)" "unprognostic (5.32e-3)" "unprognostic (3.62e-2)" "unprognostic (1.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.64e-1)" 0.7 0.1 0.3 13.0 0.2 1.9 0.2 0.3 0.3 7.2 0.4 142.2 184.0 2.1 1.9 3.3 0.1 1.8 0.7 0.3 0.2 136.5 5.8 0.6 1.3 0.5 0.5 0.3 1.4 0.0 0.0 496.7 0.5 6.1 94.1 0.1 0.6 1.0 0.1 1.4 227.2 3.4 0.3 0.5 18.0 2.1 0.6 2.1 0.2 0.0 3.8 0.8 0.4 0.5 0.0 0.1 0.1 0.4 0.0 0.0 1.0 0.2 0.0 0.0 0.0 3.2 20.5 0.0 2.7 0.0 1.7 6.2 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.3 0.1 6.4 0.2 1.9 0.0 0.0 0.0 7.7 0.3 0.2 2.2 2.5 0.1 0.9 0.0 0.3 0.8 27.1 0.6 0.2 0.1 0.6 0.0 0.2 0.1 0.1 0.2 1.0 0.1 0.2 0.1 31.2 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.3 0.3 0.3 0.2 0.5 0.5 0.5 0.3 0.6 0.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.8 272.2 0.0 2.1 0.0 517.5 15.6 0.0 7.1 1.9 0.5 0.4 43.3 0.0 0.1 3.3 63.4 0.5 13.7 4.8 5.7 0.0 0.0 0.0 2.8 0.0 0.1 129.7 2.0 0.0 1.7 18.4 0.0 1.0 0.0 0.0 66.2 0.0 0.0 0.0 0.0 3.7 532.1 0.0 0.0 0.7 957.9 145.2 0.2 0.0 0.0 0.0 0.3 3.7 1.3 0.0 0.1 3.4 0.9 0.0 117.9 0.3 APAF1 "APAF-1, CED4" ENSG00000120868 "Apoptotic peptidase activating factor 1" O14727 12 98645290-98735433 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32.0" "Cell type enhanced" "Detected in many" "monocytes: 54.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 71.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031373, CAB069399" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Golgi apparatus" "CAB069399: AB_1611908, HPA031373: AB_10602230" "unprognostic (1.32e-1)" "unprognostic (5.12e-2)" "prognostic favorable (5.90e-4)" "unprognostic (2.21e-1)" "unprognostic (3.94e-1)" "unprognostic (8.21e-3)" "unprognostic (2.03e-3)" "unprognostic (1.35e-1)" "unprognostic (2.26e-2)" "unprognostic (5.92e-3)" "unprognostic (5.63e-2)" "unprognostic (6.04e-2)" "unprognostic (9.93e-3)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (3.53e-2)" "unprognostic (3.07e-2)" 4.5 2.8 2.4 8.9 2.8 32.0 5.0 2.5 2.7 5.5 1.2 8.5 5.1 5.5 3.5 3.2 4.0 7.3 2.6 2.8 1.3 3.7 4.7 6.7 9.4 2.3 1.2 7.7 4.0 2.8 3.1 7.6 2.2 3.9 9.6 5.8 4.6 3.4 3.4 5.7 7.1 5.0 1.9 9.7 6.6 3.1 2.2 7.7 4.7 3.1 8.8 5.8 3.9 4.3 6.8 8.7 30.3 11.6 9.4 18.2 8.3 17.3 12.1 11.7 11.6 6.3 4.8 9.8 4.5 12.7 4.4 11.3 20.2 11.4 13.9 7.3 8.0 18.5 9.6 7.7 3.5 18.6 22.7 7.5 3.5 12.1 5.5 14.1 19.6 7.3 9.1 5.2 18.7 1.8 9.4 19.0 8.1 7.5 5.8 11.9 22.8 3.1 7.1 11.5 4.1 7.4 13.5 5.3 4.6 18.6 9.2 25.7 17.7 7.5 6.6 9.0 5.4 3.5 7.1 11.5 3.3 25.4 11.5 16.8 18.1 17.0 4.0 8.0 3.1 5.5 2.8 2.3 14.3 6.2 2.9 1.9 71.1 2.9 8.5 10.4 2.1 3.9 2.4 2.8 2.5 2.7 2.8 1.3 2.3 1.2 2.2 1.9 2.2 4.3 11.7 12.8 8.2 10.4 13.8 3.8 5.7 8.7 8.6 5.8 6.4 6.5 1.5 1.5 7.8 7.3 14.6 3.8 21.4 22.3 0.0 9.4 0.7 5.9 11.6 11.1 12.0 7.6 12.8 8.0 8.0 9.1 14.8 8.7 6.3 18.6 13.2 6.7 12.3 5.0 13.8 18.9 4.1 34.7 25.3 1.3 5.9 34.1 10.6 30.9 54.6 2.7 20.6 14.1 11.2 19.7 20.3 5.3 8.9 8.7 9.2 2.7 8.9 9.8 0.0 6.9 8.1 6.9 10.0 8.7 3.3 1.9 14.6 4.3 13.3 15.0 APOC2 ENSG00000234906 "Apolipoprotein C2" P02655 19 44946035-44949565 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Disease variant, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 83 "liver: 9641.4" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 1170.2" "Cancer enriched" "Detected in some" 17 "liver cancer: 49.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 30 "NK-cells: 3.2" "Group enriched" "Detected in many" 4 "Hep G2: 713.0;THP-1: 1354.4" HPA055877 Supported "Secreted to blood" NA NA 43000000000 49000000000 "Cluster 48: NK-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA055877: AB_2682953" "unprognostic (4.28e-2)" "unprognostic (7.73e-3)" "unprognostic (1.33e-1)" "unprognostic (3.66e-2)" "unprognostic (8.91e-2)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (1.96e-2)" "unprognostic (2.86e-1)" "unprognostic (1.15e-2)" "unprognostic (5.14e-8)" "unprognostic (1.32e-1)" "unprognostic (1.45e-1)" "unprognostic (1.77e-2)" "unprognostic (9.80e-3)" 1.2 5.4 49.5 1.7 55.2 1.1 5.3 55.1 116.2 4.5 44.7 4.3 41.4 1.2 4.8 2.4 4.3 3.7 0.8 50.7 69.2 16.3 9641.4 34.9 15.8 65.3 64.9 0.4 2.2 6.6 3.0 2.9 74.3 1.3 4.4 2.8 2.4 2.1 1.9 4.3 65.6 0.7 63.3 3.9 2.7 1.1 59.9 3.2 0.9 0.7 9.9 2.2 0.8 75.0 2.9 0.6 0.3 0.4 0.5 0.6 1.3 0.1 0.0 0.0 0.1 2.0 2.8 0.7 0.3 0.0 0.0 2.6 0.0 0.1 0.0 0.7 0.1 123.0 2.7 713.0 0.2 15.4 237.5 0.2 0.3 0.0 0.0 0.3 0.0 0.1 1.7 2.9 0.1 0.8 0.9 126.3 0.5 3.2 0.4 0.8 5.2 1.1 0.0 1.5 0.1 0.1 1.9 0.2 7.7 0.0 0.7 1354.4 0.0 0.3 0.6 0.8 0.8 2.3 0.9 2.2 0.2 3.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 49.5 55.2 55.1 116.2 50.7 69.2 65.3 64.9 74.3 63.3 59.9 75.0 0.1 0.0 2.3 0.0 1.2 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.1 11.5 0.0 3.7 0.0 0.1 0.1 0.0 3.9 0.0 0.0 0.0 0.1 0.3 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 26.0 0.0 13.6 1170.2 33.8 0.0 0.0 0.4 0.0 15.5 1.2 0.0 0.0 24.0 7.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 10.0 0.7 0.0 0.1 17.7 32.3 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.4 0.3 1.8 0.0 1.3 0.0 APOC4-APOC2 ENSG00000224916 "APOC4-APOC2 readthrough (NMD candidate)" 19 44942238-44949565 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1258 "liver: 2221.0" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 147.1" "Cancer enriched" "Detected in some" 17 "liver cancer: 9.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "THP-1: 4.2" HPA055877 Supported NA NA "Cluster 62: Liver - Hemostasis" "Cluster 43: THP-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" "HPA055877: AB_2682953" "unprognostic (1.45e-1)" "unprognostic (4.00e-2)" "unprognostic (1.86e-1)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (1.42e-1)" "unprognostic (1.49e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (4.73e-2)" "unprognostic (1.25e-1)" "unprognostic (1.85e-1)" "unprognostic (2.01e-4)" "unprognostic (2.28e-1)" "unprognostic (2.88e-1)" "unprognostic (5.95e-2)" "unprognostic (1.68e-2)" 0.1 0.4 0.7 0.0 0.6 0.0 0.2 0.7 0.8 0.2 0.6 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.2 0.6 0.6 0.8 2221.0 1.7 0.0 0.7 0.7 0.0 0.3 0.0 0.8 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.7 1.2 0.1 0.4 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.7 0.8 0.6 0.6 0.7 0.7 0.8 0.7 0.9 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.1 147.1 2.2 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 ARHGAP15 BM046 ENSG00000075884 "Rho GTPase activating protein 15" Q53QZ3 2 143091362-143768352 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 79.8;lymphoid tissue: 75.2" "Cell type enhanced" "Detected in many" "B-cells: 126.3;Early spermatids: 132.3;granulocytes: 88.5;Microglial cells: 250.1;NK-cells: 89.6;T-cells: 149.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 59.4;HEL: 75.8;HL-60: 124.3;MOLT-4: 82.0;NB-4: 100.4;THP-1: 131.0;U-698: 89.5;U-937: 63.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032125 Uncertain "Nucleoplasm,Golgi apparatus,Vesicles" NA NA 38000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus, Vesicles" Nucleoplasm "HPA032125: AB_10671370" "unprognostic (1.59e-2)" "unprognostic (2.40e-3)" "unprognostic (8.63e-2)" "unprognostic (2.19e-2)" "unprognostic (2.99e-1)" "unprognostic (6.62e-3)" "unprognostic (6.14e-2)" "unprognostic (2.18e-3)" "unprognostic (1.32e-2)" "unprognostic (3.58e-2)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (6.95e-5)" "unprognostic (4.40e-2)" "unprognostic (2.12e-2)" "unprognostic (4.58e-2)" "unprognostic (6.94e-2)" 6.9 5.9 1.4 27.1 1.3 79.8 7.6 2.3 2.3 4.1 1.9 7.3 6.8 2.6 9.7 4.0 2.8 11.4 5.6 1.2 2.2 4.4 10.2 9.8 59.3 3.0 1.9 1.8 1.3 1.7 1.0 4.0 2.7 4.3 7.7 1.3 4.2 5.1 1.2 2.0 15.1 3.9 1.9 44.9 7.5 7.4 2.1 75.2 4.5 2.2 46.3 11.4 4.3 4.0 0.3 0.1 4.9 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 59.4 0.2 0.1 0.1 0.1 0.2 0.1 0.3 14.6 0.0 75.8 0.5 0.1 0.0 124.3 1.2 0.0 0.0 0.2 0.2 0.1 0.0 47.0 0.3 4.4 0.0 0.1 82.0 100.4 0.3 0.0 0.1 44.7 0.6 22.7 0.0 0.1 0.2 0.4 0.3 0.2 1.0 0.1 4.5 131.0 0.6 0.4 1.2 0.1 0.2 1.0 0.3 89.5 0.7 63.9 3.9 181.8 32.0 140.1 97.7 34.3 161.6 94.3 172.8 125.7 56.3 86.2 119.0 101.7 207.2 121.4 40.5 54.3 147.7 99.9 1.4 1.3 2.3 2.3 1.2 2.2 3.0 1.9 2.7 1.9 2.1 4.0 8.2 0.0 9.6 2.0 126.3 5.6 0.1 0.0 0.0 0.3 1.8 2.0 3.9 1.5 2.5 0.0 0.0 0.2 78.9 0.3 0.0 0.1 132.3 1.8 2.3 4.3 0.0 26.3 12.2 0.0 0.3 9.7 8.6 3.5 88.5 0.0 8.6 0.8 21.3 1.7 6.8 0.0 0.0 39.9 30.9 17.5 14.9 43.0 8.8 250.1 34.9 0.4 89.6 20.6 3.2 0.0 0.0 3.4 65.8 0.2 0.0 0.7 2.2 0.3 46.0 2.7 31.6 68.4 1.2 0.4 4.5 0.3 149.2 0.1 0.2 0.2 ARHGEF1 "LBCL2, P115-RHOGEF, SUB1.5" ENSG00000076928 "Rho guanine nucleotide exchange factor 1" Q92888 19 41883173-41930150 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.4" "Cell type enhanced" "Detected in all" "dendritic cells: 156.2;NK-cells: 187.4;T-cells: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009502, HPA012924, HPA060784" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB009502: AB_667785, HPA012924: AB_1845000, HPA060784: AB_2684363" "prognostic favorable (5.92e-4)" "unprognostic (2.09e-1)" "unprognostic (8.29e-3)" "unprognostic (8.10e-3)" "unprognostic (7.63e-2)" "unprognostic (7.59e-3)" "unprognostic (4.99e-2)" "unprognostic (7.28e-2)" "unprognostic (5.88e-2)" "unprognostic (1.84e-2)" "unprognostic (6.59e-2)" "unprognostic (3.29e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (3.54e-1)" "unprognostic (1.95e-1)" "unprognostic (8.00e-2)" "unprognostic (4.65e-2)" 50.2 20.9 17.1 79.1 21.8 113.5 39.9 19.1 21.9 37.2 17.8 37.5 26.8 33.4 3.6 34.1 36.4 23.5 26.2 16.1 18.2 31.9 30.0 67.7 127.5 24.1 20.2 32.9 27.4 12.6 25.9 18.3 22.0 32.1 10.4 5.6 28.8 11.8 15.4 37.6 87.1 13.4 19.0 168.4 34.9 10.9 21.4 96.5 36.7 8.9 48.9 33.9 33.2 27.9 58.8 69.9 15.8 19.9 21.9 22.9 18.4 30.1 45.7 37.4 32.8 21.5 49.2 77.9 54.6 27.8 19.8 33.8 20.3 46.9 11.8 74.1 23.6 63.1 30.6 28.4 31.9 68.4 100.8 27.8 30.5 36.3 23.5 19.9 36.2 68.2 25.5 46.7 21.8 40.4 48.0 52.9 17.9 46.4 54.0 71.8 29.7 46.3 23.2 31.8 10.3 43.8 42.3 18.7 36.0 8.1 21.9 114.4 49.6 49.7 33.2 26.8 47.7 63.0 43.2 68.4 40.5 107.6 80.2 10.4 20.5 29.2 47.0 39.5 37.2 20.1 35.6 49.4 21.5 19.5 36.1 39.4 27.4 32.1 57.5 11.3 38.7 36.4 17.1 21.8 19.1 21.9 16.1 18.2 24.1 20.2 22.0 19.0 21.4 27.9 46.6 6.4 22.0 35.3 97.3 14.5 13.9 15.0 20.5 18.7 13.1 12.4 4.2 8.6 8.8 7.3 27.1 13.3 156.2 21.7 3.9 23.6 1.4 12.2 16.7 29.0 21.7 23.8 8.0 24.9 22.8 17.7 56.6 16.8 31.7 19.3 26.7 9.3 38.2 11.8 7.9 29.2 16.2 52.5 31.9 1.8 19.3 58.9 19.6 18.7 39.0 8.8 187.4 13.6 27.6 55.9 22.7 16.6 66.4 15.7 10.1 7.3 6.3 19.1 26.3 17.6 17.3 7.3 10.1 17.3 14.8 10.1 159.0 20.4 26.4 11.1 ARID2 "BAF200, DKFZp686G052, FLJ30619, KIAA1557" ENSG00000189079 "AT-rich interaction domain 2" Q68CP9 12 45729706-45908040 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 525.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063044 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA063044: AB_2684929" "unprognostic (8.41e-2)" "unprognostic (1.03e-1)" "unprognostic (4.02e-2)" "unprognostic (3.94e-2)" "unprognostic (4.15e-2)" "prognostic favorable (5.75e-4)" "unprognostic (1.26e-2)" "unprognostic (9.71e-2)" "unprognostic (9.04e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.47e-1)" "unprognostic (1.12e-2)" "unprognostic (9.21e-2)" "unprognostic (3.02e-1)" "unprognostic (2.00e-1)" "unprognostic (6.53e-2)" 6.4 5.2 4.6 6.7 7.8 12.6 7.5 13.8 6.9 8.5 10.2 6.8 5.0 6.9 6.5 8.4 6.4 5.4 6.0 5.0 7.3 6.3 5.4 7.8 7.5 7.8 6.4 8.3 7.2 11.7 5.0 7.2 7.6 7.4 6.0 13.2 6.7 6.2 5.9 10.0 6.6 6.1 6.0 6.9 6.2 26.1 6.2 18.7 8.8 7.7 8.9 6.8 8.0 9.8 10.3 14.5 25.3 11.1 10.5 7.3 13.7 7.0 9.9 9.6 8.9 20.7 10.4 19.8 12.7 9.8 7.0 12.1 20.6 11.8 13.6 8.8 9.8 26.1 15.9 10.1 7.2 20.7 11.5 6.0 8.8 12.1 19.1 13.4 10.0 29.1 22.4 19.9 8.6 13.4 29.9 14.7 15.1 0.0 7.7 22.9 18.0 19.0 9.1 16.9 13.6 17.4 11.4 13.0 11.1 14.5 20.0 40.8 11.8 10.3 12.3 7.0 9.2 13.2 11.8 53.6 7.9 53.2 7.4 9.4 1.1 2.7 2.4 1.3 2.5 1.0 2.1 2.5 1.5 1.1 2.0 1.9 1.4 2.1 3.4 3.3 2.0 0.9 4.6 7.8 13.8 6.9 5.0 7.3 7.8 6.4 7.6 6.0 6.2 9.8 23.3 28.9 28.4 110.4 30.8 33.8 14.4 16.3 36.5 51.6 21.7 15.4 15.6 14.3 17.3 29.5 68.8 15.5 49.0 21.3 7.9 13.2 525.4 23.2 23.8 21.1 21.0 35.1 56.7 10.0 10.5 22.0 24.5 27.7 22.1 29.3 19.2 17.3 11.2 32.0 60.3 19.0 22.4 29.8 36.7 149.3 24.8 25.6 14.2 128.4 22.4 19.9 45.3 144.3 157.9 18.8 24.6 22.6 33.8 23.7 19.1 7.4 15.4 66.2 26.3 27.0 27.2 80.2 17.0 39.3 41.3 23.4 34.8 16.4 17.9 21.0 ARL11 "ARLTS1, FLJ33930" ENSG00000152213 "ADP ribosylation factor like GTPase 11" Q969Q4 13 49628507-49633872 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "B-cells: 18.2;Hofbauer cells: 31.3;Kupffer cells: 34.8;Macrophages: 18.2;monocytes: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 38.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 7.9;HMC-1: 10.7;NB-4: 11.1;THP-1: 14.5;U-698: 6.6;U-937: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040855, HPA040887" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Intermediate filaments, Cytosol" "HPA040855: AB_10793864, HPA040887: AB_10796229" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (2.82e-1)" "unprognostic (7.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.72e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-4)" "unprognostic (1.72e-2)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (3.14e-2)" 0.8 0.8 0.5 3.9 0.5 3.5 0.7 0.6 0.7 0.6 0.8 1.0 1.2 0.2 0.2 1.0 0.3 1.1 0.4 0.4 0.6 0.1 0.6 2.2 6.9 1.0 0.7 0.2 0.1 0.3 0.3 1.9 0.8 0.2 1.5 0.1 0.6 0.2 0.3 0.6 1.9 0.7 0.7 4.8 0.6 0.3 1.0 3.7 0.4 0.4 3.9 1.3 0.8 1.2 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 0.6 0.0 5.2 10.7 0.1 0.1 0.0 0.0 0.0 0.4 5.1 0.3 0.1 0.0 1.3 4.9 11.1 0.1 0.0 0.0 5.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 3.5 14.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.6 0.0 6.3 0.0 21.8 15.3 16.3 0.1 17.9 0.2 7.9 0.3 0.3 8.1 10.1 0.8 0.4 38.0 0.8 13.4 8.6 0.3 4.4 0.5 0.5 0.6 0.7 0.4 0.6 1.0 0.7 0.8 0.7 1.0 1.2 0.9 0.0 1.1 0.0 18.2 0.3 0.3 0.2 1.2 0.7 1.0 0.9 0.6 2.8 0.0 0.0 0.0 4.7 3.4 1.7 0.0 0.0 1.7 0.1 0.1 1.2 1.2 6.9 0.0 0.0 5.1 0.3 0.0 0.1 7.6 0.0 1.8 0.6 31.3 0.0 0.0 3.4 0.0 34.8 3.5 1.3 0.3 18.2 0.0 3.7 19.2 0.3 1.0 0.0 0.1 0.1 10.2 0.0 2.9 0.1 4.2 0.1 2.3 0.5 0.0 0.3 0.2 1.5 0.3 4.1 0.0 1.5 1.2 0.5 3.1 0.4 ARL8B "ARL10C, FLJ10702, Gie1" ENSG00000134108 "ADP ribosylation factor like GTPase 8B" Q9NVJ2 3 5122249-5180911 "Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Langerhans cells: 249.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038759, HPA040515, HPA045924" Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA038759: AB_2676193, HPA040515: AB_2677017, HPA045924: AB_2679500" "unprognostic (1.37e-2)" "unprognostic (1.22e-1)" "unprognostic (3.90e-2)" "unprognostic (3.59e-1)" "unprognostic (1.12e-1)" "unprognostic (3.08e-1)" "prognostic unfavorable (3.68e-6)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (2.21e-2)" "unprognostic (6.27e-3)" "unprognostic (1.96e-1)" "prognostic favorable (4.84e-6)" "unprognostic (5.90e-3)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (1.95e-2)" 41.7 51.1 53.6 36.1 58.4 59.7 42.4 55.4 73.2 39.5 38.3 33.8 30.7 45.1 39.8 65.8 31.1 38.7 55.2 59.7 58.6 53.8 43.9 43.6 38.7 57.2 54.3 38.9 27.5 48.1 0.1 49.8 59.2 45.0 34.8 34.3 28.6 41.8 50.7 54.8 34.3 47.0 60.3 33.9 34.1 32.2 59.5 35.8 62.1 59.9 47.5 49.7 0.3 61.7 49.5 44.1 38.5 20.7 118.4 103.8 71.7 67.8 75.5 64.0 75.8 33.6 44.9 52.6 29.4 65.7 141.4 30.6 61.9 60.1 73.2 58.3 35.8 86.2 34.3 48.4 162.5 73.9 97.0 96.7 179.5 80.9 56.2 67.4 72.2 47.2 76.6 55.0 96.2 45.1 63.0 56.1 36.2 44.6 65.2 43.5 52.2 46.7 63.9 73.8 22.1 41.9 57.7 112.5 96.2 42.7 66.0 219.7 61.6 66.5 55.8 91.9 62.3 50.8 88.0 143.9 94.4 102.7 54.9 42.9 37.8 24.5 18.8 33.0 22.4 19.8 19.6 18.8 31.7 16.7 20.0 20.0 17.0 22.1 27.4 14.2 20.3 27.7 53.6 58.4 55.4 73.2 59.7 58.6 57.2 54.3 59.2 60.3 59.5 61.7 35.8 80.1 63.7 52.9 42.9 128.1 60.5 40.4 74.6 23.3 44.4 31.4 55.6 31.5 45.2 35.0 10.4 42.4 30.4 38.9 19.6 37.2 33.7 45.9 39.8 35.9 13.1 35.1 61.6 37.6 80.1 48.7 33.6 88.5 56.4 25.3 19.2 42.4 97.8 8.4 68.3 19.5 24.4 68.3 249.6 42.0 23.0 109.3 55.2 47.8 103.3 37.2 23.7 47.7 86.0 61.5 26.7 33.8 45.4 71.5 23.2 46.1 40.6 22.7 72.3 31.7 45.7 34.5 24.0 109.5 164.7 173.1 36.8 23.8 16.6 123.3 ARPC4 "ARC20, p20-Arc" ENSG00000241553 "Actin related protein 2/3 complex subunit 4" P59998 3 9792495-9807101 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 468.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 5900000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "unprognostic (2.54e-1)" "unprognostic (4.69e-2)" "unprognostic (8.93e-2)" "unprognostic (2.97e-2)" "unprognostic (2.49e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.79e-1)" "unprognostic (6.43e-2)" "unprognostic (2.05e-1)" "unprognostic (3.57e-1)" "unprognostic (2.99e-2)" "unprognostic (1.18e-1)" "unprognostic (5.20e-2)" "unprognostic (4.83e-2)" "unprognostic (7.89e-2)" "prognostic favorable (2.34e-4)" 100.8 97.8 136.1 135.3 136.2 148.5 84.2 128.9 146.3 86.3 121.5 126.1 98.7 93.2 66.7 139.0 82.6 68.8 71.3 150.5 138.1 118.7 81.7 91.7 171.5 136.1 137.2 69.9 58.4 76.9 54.3 77.5 138.3 69.9 117.7 18.2 69.7 70.9 91.8 101.0 98.0 113.0 136.7 143.3 83.5 38.0 144.9 132.6 69.6 61.2 205.1 121.7 84.9 138.4 151.7 168.9 150.2 95.5 189.9 157.8 402.2 225.1 238.2 204.5 177.6 106.8 199.3 106.2 126.6 326.5 201.1 95.8 102.9 182.7 183.6 202.2 67.2 315.6 156.0 120.7 209.9 291.8 410.6 173.7 166.9 245.6 149.4 171.5 239.0 59.1 165.5 92.2 327.0 302.3 244.2 261.1 278.5 201.9 200.2 209.9 105.9 160.8 248.6 198.0 62.9 209.9 137.1 155.9 161.5 128.3 189.5 450.6 243.8 188.8 87.8 194.2 329.4 60.8 197.1 293.0 272.7 224.2 286.4 300.2 377.6 431.4 279.8 469.0 230.7 210.3 232.4 230.4 314.4 194.9 161.7 218.0 639.5 218.0 457.8 432.2 274.6 480.6 136.1 136.2 128.9 146.3 150.5 138.1 136.1 137.2 138.3 136.7 144.9 138.4 91.1 16.0 42.0 0.0 104.0 68.2 79.5 37.7 17.6 12.9 56.2 38.4 24.3 44.3 32.2 58.8 8.4 117.4 228.5 213.3 72.4 136.0 9.8 42.8 70.9 79.5 112.9 56.8 0.0 126.1 240.3 59.7 44.9 62.1 104.1 69.4 81.4 54.7 340.3 23.5 0.0 151.8 30.5 237.1 155.8 7.4 49.4 210.3 78.2 0.0 468.8 40.7 300.7 0.0 0.0 171.2 182.6 66.2 31.7 75.3 118.8 136.2 29.1 13.3 39.5 43.8 82.4 12.9 32.0 33.9 65.8 169.1 132.1 103.1 154.4 87.9 ARPC4-TTLL3 ENSG00000250151 "ARPC4-TTLL3 readthrough" 3 9793082-9835401 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.4;B-cells: 1.8;Basal squamous epithelial cells: 1.8;Erythroid cells: 3.0;Gastric mucus-secreting cells: 2.0;Macrophages: 1.5;Plasma cells: 1.7;T-cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "unprognostic (9.59e-3)" "unprognostic (7.61e-2)" "unprognostic (6.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.55e-3)" "unprognostic (2.86e-2)" "unprognostic (1.95e-2)" "unprognostic (2.78e-1)" "unprognostic (4.13e-2)" "unprognostic (3.31e-1)" "unprognostic (6.67e-2)" "unprognostic (1.82e-1)" "unprognostic (3.42e-4)" "unprognostic (5.49e-2)" "unprognostic (4.06e-1)" "unprognostic (2.58e-1)" "unprognostic (2.37e-4)" 2.0 1.6 1.4 2.9 1.4 6.7 1.5 1.4 3.2 2.0 1.4 1.5 2.2 1.2 0.6 2.0 1.4 1.3 1.5 1.4 1.6 1.6 1.0 1.9 2.2 1.7 1.5 1.5 0.8 1.0 1.6 1.1 1.5 1.3 0.9 0.6 1.3 0.7 1.6 2.0 2.0 1.5 1.4 3.2 1.3 1.6 1.9 2.3 1.3 0.5 2.1 1.6 1.6 1.7 2.9 0.4 3.0 1.2 3.1 4.6 8.0 3.1 3.3 2.1 2.3 1.4 1.0 3.8 1.4 9.6 4.2 1.5 3.1 2.5 2.6 6.8 1.5 6.1 1.5 0.9 4.3 6.1 9.4 5.6 3.5 5.5 2.4 2.8 3.1 5.8 4.7 4.1 3.1 0.0 3.8 4.9 3.3 1.7 2.1 5.6 2.5 0.1 4.0 3.1 1.6 2.6 2.1 4.3 3.1 1.7 0.8 13.4 4.0 1.8 2.1 3.7 4.5 4.6 6.7 9.6 3.9 5.7 3.9 0.8 2.9 3.0 2.7 2.8 1.7 1.3 1.8 1.4 3.0 1.3 1.4 1.5 3.2 1.3 3.3 2.7 1.4 3.8 1.4 1.4 1.4 3.2 1.4 1.6 1.7 1.5 1.5 1.4 1.9 1.7 0.1 0.0 2.4 0.0 1.8 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.1 0.3 0.0 3.0 0.2 0.0 0.1 1.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.0 0.1 ASH1L "ASH1, ASH1L1, huASH1, KMT2H" ENSG00000116539 "ASH1 like histone lysine methyltransferase" Q9NR48 1 155335268-155563162 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004806 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Golgi apparatus" "HPA004806: AB_1845087" "unprognostic (2.98e-1)" "unprognostic (3.15e-2)" "unprognostic (1.10e-1)" "unprognostic (1.70e-2)" "unprognostic (2.05e-2)" "unprognostic (4.75e-2)" "unprognostic (1.42e-1)" "unprognostic (1.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.59e-1)" "unprognostic (1.07e-1)" "unprognostic (6.84e-2)" "prognostic favorable (3.80e-4)" "unprognostic (2.95e-1)" "unprognostic (1.62e-1)" "unprognostic (2.45e-2)" "unprognostic (1.94e-1)" 14.1 12.8 21.3 8.5 23.4 11.9 16.8 27.0 25.7 14.4 14.8 13.0 9.7 14.4 20.8 9.2 11.4 9.0 12.6 23.8 19.2 13.9 10.0 10.3 10.9 18.7 19.8 21.3 9.9 18.2 8.4 10.3 18.9 15.7 11.5 26.2 14.8 15.4 30.3 20.4 10.2 12.7 19.3 10.5 11.9 6.8 20.7 12.1 15.8 24.3 9.7 11.7 10.0 23.4 17.2 12.3 9.5 9.4 28.0 22.8 9.6 14.7 13.5 8.3 6.5 10.5 12.3 5.4 14.2 17.0 5.4 19.2 13.6 12.6 13.6 7.6 8.9 8.0 13.2 9.8 14.5 8.8 6.6 16.2 18.0 13.6 15.0 17.1 11.0 6.0 12.3 8.3 18.8 19.0 6.4 8.8 8.3 28.8 13.1 6.1 18.5 10.4 18.6 16.0 9.1 14.3 20.1 25.9 12.9 9.3 16.6 26.6 17.4 13.6 15.8 13.4 17.9 8.0 5.3 8.9 10.7 9.1 13.1 1.0 0.4 0.8 0.7 0.2 0.5 0.9 0.5 0.5 0.2 0.8 0.8 0.5 1.0 0.6 0.1 0.7 0.9 0.2 21.3 23.4 27.0 25.7 23.8 19.2 18.7 19.8 18.9 19.3 20.7 23.4 96.5 60.9 103.2 171.7 108.3 103.9 97.4 52.9 109.3 147.6 75.9 58.3 107.8 50.1 82.7 51.5 202.3 53.6 83.3 76.2 17.6 41.5 25.9 72.0 107.4 77.6 67.5 46.7 220.6 39.8 25.2 93.7 101.4 87.9 81.1 72.3 63.1 39.0 24.6 114.4 211.8 59.0 26.4 42.1 106.9 22.8 102.2 69.1 53.4 203.3 85.2 68.4 89.6 190.5 265.0 37.5 64.8 118.8 110.1 112.0 68.9 31.0 47.1 116.7 98.6 134.4 104.6 85.6 56.1 80.9 112.0 76.2 98.7 87.3 60.2 111.6 AZU1 "AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC" ENSG00000172232 "Azurocidin 1" P20160 19 825097-832018 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Heparin-binding, Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "bone marrow: 1578.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.5;Breast myoepithelial cells: 4.6;Endometrial ciliated cells: 8.9;Erythroid cells: 8.8;Respiratory ciliated cells: 4.5;Skeletal myocytes: 5.7;Spermatogonia: 6.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "neutrophil: 3.3" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.3" "Cell line enriched" "Detected in some" 15 "THP-1: 659.5" "Not detected" "Not detected" "HPA055851, HPA075964" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 320000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA055851: AB_2682943, HPA075964: " "unprognostic (1.12e-2)" "unprognostic (3.71e-2)" "unprognostic (4.44e-2)" "unprognostic (8.85e-3)" "unprognostic (1.62e-2)" "unprognostic (1.29e-1)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (3.32e-1)" "unprognostic (4.22e-3)" "unprognostic (2.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-6)" "unprognostic (1.11e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-2)" "unprognostic (3.04e-2)" 0.8 0.2 0.4 0.0 0.4 1578.1 1.5 0.2 0.9 0.2 0.2 0.2 0.0 0.5 0.0 0.1 1.4 0.0 2.0 0.4 0.3 0.4 2.8 15.9 0.6 0.3 0.3 0.2 0.2 0.0 0.9 0.9 0.4 0.4 0.0 0.0 2.6 0.0 0.5 0.6 0.2 0.0 0.2 33.1 0.2 2.4 0.4 3.1 0.5 0.0 0.0 0.3 0.2 0.3 1.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 44.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.4 0.6 659.5 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.6 0.0 34.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 0.1 0.4 0.4 0.2 0.9 0.4 0.3 0.3 0.3 0.4 0.2 0.4 0.3 3.5 0.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.0 4.5 4.6 0.7 0.0 0.5 0.0 0.0 0.2 2.8 0.6 0.0 0.1 0.0 8.9 1.2 1.0 0.0 8.8 0.8 0.0 0.3 0.8 0.0 2.3 0.0 0.1 0.0 0.4 3.2 0.0 1.4 0.4 0.0 3.7 0.4 0.7 0.0 3.2 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.2 0.0 4.5 0.0 0.0 5.7 1.2 0.1 6.4 0.9 0.1 0.0 1.0 0.0 0.6 0.0 B3GNTL1 B3GNT8 ENSG00000175711 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1" Q67FW5 17 82942155-83051810 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 19.9;Respiratory ciliated cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 25.1;HL-60: 27.0;THP-1: 25.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023585, HPA024547" Supported Approved "Nucleoli,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli, Nucleoli fibrillar center" Vesicles "HPA023585: AB_2061075, HPA024547: AB_1845240" "unprognostic (1.51e-2)" "unprognostic (9.84e-2)" "unprognostic (4.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.38e-1)" "unprognostic (8.11e-2)" "unprognostic (2.61e-7)" "unprognostic (9.95e-2)" "unprognostic (2.62e-1)" "unprognostic (1.62e-1)" "unprognostic (8.74e-2)" "unprognostic (2.80e-2)" "unprognostic (4.17e-9)" "unprognostic (2.02e-1)" "unprognostic (1.47e-1)" "unprognostic (1.88e-1)" "unprognostic (3.39e-3)" 2.9 2.8 1.8 2.9 2.1 7.8 2.4 1.4 2.3 3.5 3.9 2.0 1.7 3.7 1.2 2.4 3.7 1.3 3.0 1.9 1.4 1.9 2.4 3.0 2.3 1.3 1.5 3.9 2.3 0.8 2.6 1.4 1.6 2.6 0.9 0.5 2.1 1.5 3.8 2.3 2.1 1.8 1.3 4.2 2.0 3.0 2.1 2.3 2.4 1.4 1.1 3.1 2.5 1.6 11.9 7.8 0.2 3.7 2.1 6.6 4.7 4.2 3.7 4.8 3.7 4.7 25.1 5.8 8.1 5.2 11.7 2.2 1.9 0.0 4.1 8.9 5.1 12.2 12.6 16.0 7.5 27.0 0.5 2.4 2.1 2.9 4.8 2.4 5.9 8.9 5.4 5.5 3.9 2.7 7.6 10.3 1.8 8.1 5.6 9.8 0.9 0.4 2.7 2.5 2.4 0.9 3.6 2.7 3.7 3.4 0.0 25.5 9.7 9.2 6.2 1.4 7.6 1.1 2.9 4.4 10.3 3.6 1.3 3.0 6.0 1.0 2.8 5.9 4.4 3.0 4.4 3.3 10.4 5.5 3.9 4.7 19.0 3.2 3.2 4.1 13.5 4.0 1.8 2.1 1.4 2.3 1.9 1.4 1.3 1.5 1.6 1.3 2.1 1.6 2.6 3.2 4.5 4.6 2.9 1.0 2.0 4.4 3.4 3.5 3.0 3.0 2.8 1.5 6.4 5.5 4.2 5.7 3.6 1.3 1.9 1.9 15.3 6.8 4.2 2.3 1.2 7.6 11.3 1.0 3.1 4.0 3.1 1.9 7.0 7.6 1.4 2.0 7.7 3.3 9.2 1.5 6.1 7.3 2.8 19.9 3.1 8.9 1.8 6.5 5.5 1.3 8.2 5.0 4.7 2.1 2.7 4.9 5.2 2.8 0.2 2.4 20.7 3.5 0.0 2.5 2.3 0.9 5.0 5.6 1.7 1.9 6.8 4.8 3.5 2.1 BHLHE22 "Beta3, BHLHB5, CAGL85, TNRC20" ENSG00000180828 "Basic helix-loop-helix family member e22" Q8NFJ8 8 64580365-64583627 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 23.2" "Cell type enriched" "Detected in some" 14 "Bipolar cells: 64.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 23 "THP-1: 78.4" "Group enriched" "Detected in all" 5 "amygdala: 30.7;cerebellum: 30.7;cerebral cortex: 22.7;hippocampal formation: 46.3;white matter: 13.1" "HPA064128, HPA064872, HPA067500" Enhanced Approved "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA064128: AB_2685195, HPA064872: AB_2685377, HPA067500: AB_2685855" "unprognostic (9.17e-2)" "unprognostic (1.11e-2)" "unprognostic (5.44e-2)" "unprognostic (2.28e-5)" "unprognostic (7.22e-3)" "unprognostic (6.47e-4)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (6.58e-2)" "unprognostic (1.52e-1)" "unprognostic (3.71e-2)" "unprognostic (2.86e-7)" "unprognostic (3.20e-2)" "unprognostic (2.29e-1)" "unprognostic (6.72e-3)" "unprognostic (1.86e-1)" 2.0 0.5 8.9 1.4 6.6 0.0 1.5 12.1 22.4 2.3 0.4 1.3 0.4 0.3 0.1 0.9 0.8 0.4 0.3 23.2 1.5 0.2 0.5 2.0 0.7 5.5 1.5 0.2 0.7 0.1 1.4 0.0 2.6 0.4 0.5 4.4 0.5 2.3 0.1 0.8 1.4 0.4 1.4 1.4 0.5 0.2 1.1 0.3 0.7 0.0 0.6 1.2 2.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 78.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 6.6 12.1 22.4 23.2 1.5 5.5 1.5 2.6 1.4 1.1 1.8 0.3 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 64.7 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 1.2 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.0 3.4 0.2 0.0 0.0 0.6 1.5 0.0 1.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.2 2.9 0.0 0.4 0.1 1.6 0.0 0.1 0.0 0.0 0.0 BMP8B "BMP8, OP-2" ENSG00000116985 "Bone morphogenetic protein 8b" P34820 1 39757182-39788865 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.4" "Group enriched" "Detected in many" 5 "Early spermatids: 72.1;Late spermatids: 106.5;Plasma cells: 38.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "THP-1: 120.5;U-266/70: 33.7;U-266/84: 52.5;WM-115: 56.7" HPA047254 Approved Vesicles "Secreted to blood" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA047254: " "unprognostic (1.53e-3)" "unprognostic (7.29e-2)" "unprognostic (2.18e-1)" "unprognostic (6.64e-3)" "unprognostic (8.79e-2)" "unprognostic (3.44e-2)" "unprognostic (7.27e-2)" "unprognostic (7.56e-2)" "unprognostic (1.88e-1)" "unprognostic (7.41e-2)" "unprognostic (2.68e-1)" "unprognostic (4.72e-4)" "unprognostic (1.79e-2)" "unprognostic (3.15e-1)" "unprognostic (9.67e-2)" "unprognostic (8.68e-3)" "unprognostic (4.82e-1)" 1.7 5.6 2.1 1.5 2.0 0.8 0.9 1.1 5.3 2.1 0.1 3.8 5.4 1.5 3.3 1.0 1.3 0.8 1.0 2.8 1.8 0.9 0.6 1.3 0.7 13.4 3.5 0.8 7.0 1.8 2.7 1.5 3.3 2.4 2.7 0.5 1.7 2.5 0.6 2.0 4.1 0.7 2.8 1.5 1.8 2.2 2.6 0.4 4.7 1.6 0.7 1.6 2.1 4.7 2.7 4.5 0.3 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.8 5.4 0.1 1.8 0.0 0.7 0.4 4.2 0.0 0.0 1.0 5.8 4.9 3.6 0.3 0.1 0.6 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.6 18.1 0.2 3.7 0.1 2.5 0.3 2.8 1.8 2.7 15.9 5.7 4.0 2.7 13.0 3.4 4.3 0.3 13.4 0.9 3.1 120.5 0.0 0.1 0.3 1.1 0.2 33.7 52.5 2.0 0.0 3.7 56.7 0.2 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 2.1 2.0 1.1 5.3 2.8 1.8 13.4 3.5 3.3 2.8 2.6 4.7 0.0 0.0 1.8 0.0 3.5 0.4 0.6 0.2 0.0 0.5 1.1 0.8 1.2 0.0 0.8 0.0 0.0 0.0 0.9 13.5 0.0 1.0 72.1 1.1 0.6 0.4 1.2 0.0 0.4 3.4 0.0 1.7 1.1 2.3 0.0 0.3 0.4 0.0 0.4 0.0 0.3 2.0 0.0 0.0 2.7 106.5 1.2 0.8 5.4 0.0 0.7 0.1 0.0 8.0 1.8 2.2 2.2 0.7 38.9 0.4 5.0 0.0 0.4 0.5 0.0 1.8 3.4 0.8 0.4 0.4 0.0 0.0 0.7 0.1 1.2 0.8 BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 139.8;intestine: 48.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.8;Macrophages: 33.3;monocytes: 80.1;Proximal enterocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 257.7;neutrophil: 292.7" "Group enriched" "Detected in many" 95 "dendritic cells: 78.9;granulocytes: 292.7;monocytes: 257.7" "Cell line enhanced" "Detected in many" "THP-1: 76.0;TIME: 40.4;U-937: 52.5;WM-115: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" NA NA 190000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" 21.2 2.7 1.9 13.7 2.1 139.8 9.4 2.1 4.7 11.0 1.6 8.3 48.6 6.3 2.9 4.6 7.9 18.2 19.1 2.1 2.0 17.0 8.5 12.7 7.1 1.9 1.4 9.3 3.1 1.7 1.3 13.7 2.2 3.7 9.7 1.0 3.9 4.6 2.7 5.0 29.3 9.7 0.8 18.6 3.2 2.7 3.0 3.9 4.9 6.8 3.5 16.8 7.4 3.3 0.6 10.5 1.2 1.0 28.8 7.0 1.6 21.0 2.1 20.4 22.2 0.3 12.1 0.8 1.9 12.2 0.6 0.3 3.3 0.5 17.2 0.8 0.7 5.6 0.8 0.6 6.7 7.2 15.1 5.7 1.5 12.9 1.0 0.9 3.0 5.0 0.7 0.5 12.5 0.3 2.3 4.3 2.7 0.9 2.2 0.8 1.8 0.5 0.5 0.6 1.4 4.3 0.4 0.7 14.2 1.2 0.5 76.0 40.4 0.6 1.0 7.9 1.1 0.6 0.2 0.7 2.7 52.5 44.8 41.8 257.7 20.8 1.1 97.4 1.7 2.2 0.9 0.8 78.9 0.9 1.1 0.7 292.7 0.4 73.9 26.6 1.0 109.8 1.9 2.1 2.1 4.7 2.1 2.0 1.9 1.4 2.2 0.8 3.0 3.3 5.4 3.2 3.7 1.3 0.3 4.6 0.8 0.1 1.8 0.6 1.2 2.0 1.5 2.8 1.0 1.8 0.0 16.0 5.5 3.7 1.9 4.4 4.4 8.0 9.9 3.8 1.2 2.5 0.7 2.5 24.0 22.5 0.0 16.2 15.9 20.6 6.4 2.1 40.8 0.0 0.7 8.1 0.0 26.3 11.5 1.2 3.1 33.3 14.2 3.7 80.1 0.6 3.1 0.5 3.6 1.1 11.9 2.2 0.4 0.6 79.0 9.6 3.0 0.2 6.6 3.9 15.5 2.5 1.4 1.7 3.0 7.1 1.8 1.4 23.2 3.3 C1orf127 FLJ37118 ENSG00000175262 "Chromosome 1 open reading frame 127" 1 10946471-10982037 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 4.4;skeletal muscle: 16.5" "Cell type enriched" "Detected in some" 9 "Enteroendocrine cells: 20.4" "Cancer enriched" "Detected in single" 9 "pancreatic cancer: 2.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.3" "Lineage enhanced" "Detected in single" "dendritic cells: 1.3" "Cell line enriched" "Detected in single" 4 "THP-1: 2.6" "Not detected" "Not detected" HPA027654 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear speckles, Cytosol" "HPA027654: AB_10611814" "unprognostic (1.82e-2)" "unprognostic (8.57e-2)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.17e-2)" "unprognostic (2.03e-2)" "unprognostic (3.81e-2)" "unprognostic (1.32e-2)" "unprognostic (9.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.82e-2)" "unprognostic (8.47e-2)" "unprognostic (1.59e-2)" "unprognostic (3.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.04e-1)" "unprognostic (4.03e-1)" 0.2 0.6 0.3 0.1 0.3 0.1 0.1 1.2 0.7 0.1 0.2 0.3 0.7 0.0 0.1 0.6 0.0 0.3 0.6 0.2 0.3 0.0 0.2 0.4 0.6 0.2 0.5 0.0 4.4 0.1 0.2 0.2 0.3 0.1 0.6 0.0 0.2 0.0 16.5 0.0 0.3 0.0 0.2 0.6 1.9 0.5 0.7 0.1 0.2 3.7 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.3 1.2 0.7 0.2 0.3 0.2 0.5 0.3 0.2 0.7 0.3 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.3 0.8 0.0 0.8 0.6 0.1 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C1orf43 "DKFZp586G1722, NICE-3" ENSG00000143612 "Chromosome 1 open reading frame 43" Q9BWL3 1 154206696-154220637 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010725 Approved Supported Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA010725: AB_1078341" "unprognostic (3.90e-2)" "unprognostic (1.22e-2)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.87e-2)" "unprognostic (6.15e-3)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.72e-1)" "unprognostic (2.78e-1)" "unprognostic (2.64e-2)" "unprognostic (3.51e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (2.89e-1)" "unprognostic (1.75e-2)" "unprognostic (1.23e-1)" 126.7 131.9 148.0 72.6 160.4 77.3 119.7 158.9 168.6 90.5 145.1 109.3 118.4 80.7 115.3 107.7 100.5 86.7 179.7 141.7 158.3 187.7 222.0 106.3 82.0 153.0 152.6 77.1 149.7 149.6 85.7 67.6 151.6 94.9 121.2 135.7 99.1 90.2 477.6 105.8 106.1 90.6 152.4 81.6 117.2 62.0 154.2 92.0 108.7 368.2 99.0 113.9 85.7 169.3 183.5 188.4 156.5 185.1 231.1 230.7 96.2 180.2 309.4 205.0 188.4 127.7 249.8 237.9 268.1 162.9 177.5 182.4 218.5 163.3 147.2 191.1 232.1 184.9 182.6 168.1 357.9 235.4 209.6 187.1 376.6 219.8 449.7 278.6 239.9 262.6 199.1 220.1 268.4 287.5 177.4 212.1 302.3 414.8 282.3 159.8 145.8 435.9 256.0 180.6 254.8 333.5 161.1 420.8 624.9 180.8 416.6 513.5 164.4 157.9 133.6 193.3 229.7 403.5 424.1 227.6 263.4 234.4 430.9 189.9 204.8 134.3 85.9 185.4 102.4 100.3 98.7 93.3 211.5 90.0 102.8 86.8 114.9 83.3 174.6 156.2 154.3 242.7 148.0 160.4 158.9 168.6 141.7 158.3 153.0 152.6 151.6 152.4 154.2 169.3 107.2 115.4 100.8 27.1 92.1 94.2 128.4 155.3 81.4 112.6 132.9 114.4 135.8 128.7 115.4 71.7 29.2 87.2 86.8 106.1 252.4 171.5 247.1 69.6 62.1 105.4 122.0 110.0 27.3 202.0 125.1 80.2 77.5 58.1 62.1 79.5 100.6 146.9 178.9 58.9 30.8 133.9 116.0 162.5 116.1 171.8 65.0 131.5 124.5 16.9 155.4 107.0 64.9 26.2 50.5 162.8 131.6 74.9 104.1 186.1 218.3 262.1 85.7 89.5 72.3 75.8 86.6 70.7 59.2 113.9 100.6 126.1 76.7 117.4 133.6 167.5 CA7 ENSG00000168748 "Carbonic anhydrase 7" P43166 16 66844414-66854153 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 57.0" "Cell type enriched" "Detected in some" 40 "Paneth cells: 3026.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 1.1;THP-1: 1.9" "Region enhanced" "Detected in all" "cerebellum: 67.2" "Low region specificity" "Detected in many" HPA047237 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047237: AB_2679994" "unprognostic (8.77e-4)" "unprognostic (5.23e-4)" "unprognostic (1.57e-1)" "unprognostic (1.96e-2)" "unprognostic (2.19e-1)" "unprognostic (2.16e-2)" "unprognostic (7.90e-2)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "unprognostic (9.62e-2)" "unprognostic (1.69e-2)" "unprognostic (7.12e-3)" "unprognostic (8.47e-2)" "unprognostic (5.20e-1)" "unprognostic (1.90e-2)" "unprognostic (6.46e-2)" 0.0 0.0 5.1 0.2 6.7 0.0 0.1 4.8 10.7 0.0 2.1 57.0 6.9 0.1 0.9 0.1 0.0 0.0 0.0 8.0 3.1 0.0 0.0 0.0 0.0 3.8 3.5 0.0 0.0 0.0 0.1 0.0 3.5 0.0 48.6 0.0 0.0 0.2 0.0 0.0 10.0 1.1 2.6 0.0 0.0 0.5 4.7 0.1 0.0 0.2 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 6.7 4.8 10.7 8.0 3.1 3.8 3.5 3.5 2.6 4.7 5.6 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 74.2 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.1 16.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3026.3 0.0 0.0 0.5 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 39.9 0.1 CAP1 CAP ENSG00000131236 "Cyclase associated actin cytoskeleton regulatory protein 1" Q01518 1 40040233-40072649 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 832.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "THP-1: 1954.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030124 Approved Approved Cytosol NA NA 73000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA030124: AB_10600799" "unprognostic (1.80e-3)" "unprognostic (1.23e-3)" "unprognostic (5.68e-2)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (1.44e-6)" "unprognostic (5.37e-2)" "unprognostic (4.87e-1)" "unprognostic (1.98e-1)" "unprognostic (3.33e-3)" "unprognostic (1.09e-1)" "unprognostic (6.22e-2)" "unprognostic (1.39e-1)" "unprognostic (7.08e-2)" "unprognostic (1.26e-1)" "unprognostic (3.44e-1)" 175.2 96.8 78.6 275.0 92.3 314.9 137.5 87.6 95.3 131.2 77.8 223.7 143.7 207.2 100.4 196.2 134.2 135.3 82.3 82.6 85.3 130.7 124.4 181.7 266.8 98.0 87.6 87.7 67.8 115.1 62.8 184.2 94.4 105.0 210.4 63.4 117.4 140.1 48.1 120.2 165.0 236.6 89.7 206.1 147.8 75.0 91.5 186.8 106.8 56.0 326.4 231.2 130.4 107.9 435.9 185.1 216.4 134.8 310.6 290.5 338.9 749.8 437.7 398.9 399.9 272.5 440.1 339.5 295.7 598.7 275.7 267.1 265.8 535.7 548.1 461.6 164.9 520.2 188.7 216.8 286.4 326.9 1417.9 297.5 280.6 612.5 345.4 456.5 346.4 185.7 201.6 215.0 621.7 129.2 265.4 194.9 367.7 312.1 207.9 197.0 297.6 198.6 451.3 452.0 107.5 222.9 308.7 366.4 523.8 443.1 170.0 1954.7 628.9 347.3 317.9 188.0 641.4 178.9 381.8 301.0 451.5 353.8 466.9 1371.5 776.8 2592.7 665.8 1097.6 526.2 328.0 473.4 643.9 868.3 325.6 397.1 537.9 1560.4 479.8 1402.6 333.8 701.5 1838.4 78.6 92.3 87.6 95.3 82.6 85.3 98.0 87.6 94.4 89.7 91.5 107.9 132.5 121.8 90.9 17.6 179.0 112.3 149.0 236.2 48.9 40.8 81.8 89.9 15.7 80.1 161.8 114.0 27.1 212.9 206.9 372.1 111.6 364.1 411.3 94.5 109.8 163.2 76.1 73.4 22.3 272.3 439.6 107.9 74.5 182.9 229.1 70.9 167.0 77.0 426.0 42.1 16.7 180.2 142.4 411.6 333.3 480.3 88.0 390.8 99.6 25.3 606.5 160.9 315.1 13.0 30.4 832.7 202.0 176.8 117.1 130.7 159.7 142.1 105.6 49.5 164.3 68.9 207.1 118.0 67.9 97.2 132.8 237.8 238.0 74.8 151.5 221.4 CCDC27 FLJ32825 ENSG00000162592 "Coiled-coil domain containing 27" Q2M243 1 3746460-3771645 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "testis: 16.9" "Group enriched" "Detected in some" 63 "Early spermatids: 87.6;Late spermatids: 27.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "THP-1: 1.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "basal ganglia: 1.1" HPA044395 Approved Nucleoplasm,Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol Nucleoplasm "HPA044395: AB_10962987" "unprognostic (1.36e-1)" "unprognostic (6.67e-3)" "unprognostic (3.23e-4)" "unprognostic (3.13e-2)" "unprognostic (3.42e-1)" "unprognostic (2.07e-1)" "unprognostic (1.79e-2)" "unprognostic (7.18e-2)" "unprognostic (1.20e-1)" "unprognostic (2.17e-2)" "unprognostic (2.54e-3)" "unprognostic (2.66e-2)" "unprognostic (2.46e-2)" "unprognostic (2.28e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 16.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 27.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCER2 ENSG00000262484 "Coiled-coil glutamate rich protein 2" I3L3R5 19 38908980-38912158 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 8 "Melanocytes: 617.2" "Group enriched" "Detected in many" 5 "glioma: 5.1;testis cancer: 1.9;urothelial cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.4;THP-1: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069716 Uncertain "Secreted - unknown location" NA NA 8800 "Cluster 27: Brain & Skin - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA069716: AB_2686183" "unprognostic (6.58e-2)" "unprognostic (2.24e-2)" "unprognostic (5.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (2.76e-3)" "unprognostic (3.88e-2)" "unprognostic (2.16e-1)" "unprognostic (5.97e-2)" "unprognostic (1.45e-1)" "unprognostic (4.08e-3)" "unprognostic (3.82e-2)" "unprognostic (1.01e-9)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.32e-4)" 0.5 0.6 2.2 0.2 2.4 0.7 0.8 2.3 3.4 1.2 1.8 0.9 0.3 0.7 0.3 1.2 1.1 0.1 0.9 2.3 2.2 1.8 2.9 0.5 0.3 2.9 2.2 0.7 0.5 0.2 2.5 0.1 2.4 1.4 0.1 1.0 0.9 0.2 2.3 4.2 0.9 0.1 2.1 1.1 0.6 4.9 2.2 0.4 1.2 0.0 0.1 0.9 0.8 2.4 0.1 1.4 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.5 1.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.0 0.6 0.5 0.1 0.2 0.1 0.0 0.0 0.0 0.9 0.2 0.9 0.0 0.9 0.2 0.4 0.3 0.0 0.2 0.7 0.1 0.2 0.1 0.6 0.4 0.2 0.1 0.1 0.0 0.1 1.0 1.4 0.0 0.0 0.7 0.0 0.0 0.6 0.5 0.2 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 2.3 3.4 2.3 2.2 2.9 2.2 2.4 2.1 2.2 2.4 0.1 3.2 0.0 3.9 0.1 76.9 0.1 0.1 0.0 2.5 0.4 0.5 0.4 1.5 0.1 1.8 4.2 0.4 0.4 0.3 0.0 0.0 1.4 0.3 0.2 0.6 1.2 0.4 2.3 0.0 0.1 0.8 0.0 0.5 0.0 0.3 0.0 0.6 0.2 0.0 3.3 0.2 0.0 0.3 7.2 4.9 0.3 0.2 617.2 0.0 0.0 1.3 0.0 3.5 2.2 0.1 0.2 0.0 0.0 0.1 0.2 0.2 0.4 3.8 0.0 0.4 0.7 1.1 2.1 0.0 3.0 0.3 0.4 0.2 0.6 0.1 CCL23 "Ckb-8, CKb8, MIP-3, MPIF-1, SCYA23" ENSG00000274736 "C-C motif chemokine ligand 23" P55773 17 36013056-36017972 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Hepatic stellate cells: 243.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 163 "eosinophil: 183.7" "Lineage enriched" "Detected in many" 163 "granulocytes: 183.7" "Group enriched" "Detected in some" 4 "HEL: 17.6;THP-1: 37.4" HPA042015 Uncertain "Secreted to blood" NA NA 937000 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042015: AB_10794039" "unprognostic (1.65e-3)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (9.50e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-1)" "unprognostic (1.20e-4)" "unprognostic (2.17e-1)" "unprognostic (6.49e-2)" "unprognostic (1.08e-2)" "unprognostic (7.05e-2)" "unprognostic (6.93e-2)" "unprognostic (1.35e-3)" "unprognostic (2.18e-1)" "unprognostic (2.76e-1)" "unprognostic (1.20e-2)" "unprognostic (1.95e-1)" 7.9 6.7 0.0 7.0 0.0 3.7 7.3 0.0 0.2 18.5 0.1 4.3 0.2 14.8 1.6 4.7 11.9 3.3 0.7 0.0 0.0 12.0 7.5 21.4 1.6 0.0 0.0 2.9 1.0 0.0 0.3 0.3 0.0 8.6 8.7 0.0 3.5 0.3 0.5 3.6 9.3 10.8 0.0 14.1 3.3 0.6 0.1 0.8 3.1 0.1 1.3 5.5 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 2.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 1.0 0.7 183.7 0.1 0.7 0.0 1.0 0.0 0.4 0.7 0.0 0.0 0.4 0.7 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.5 3.2 2.3 0.0 0.9 1.7 0.4 0.0 0.0 0.0 0.1 0.3 0.2 1.5 0.6 0.0 0.0 0.0 0.7 1.6 0.0 0.0 1.6 0.0 0.2 44.6 0.0 5.7 0.0 0.0 0.0 0.7 0.0 0.0 10.1 0.0 243.8 2.6 7.0 0.0 0.0 0.5 0.0 14.7 2.7 0.1 0.0 3.7 1.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 21.4 0.0 0.1 0.1 0.5 0.1 1.5 0.0 0.0 0.0 0.5 0.0 0.1 0.1 2.7 0.3 0.6 0.0 4.2 0.2 CD209 "CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1" ENSG00000090659 "CD209 molecule" Q9NNX6 19 7739993-7747564 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 34.2;placenta: 22.8" "Group enriched" "Detected in some" 4 "Kupffer cells: 15.6;Langerhans cells: 14.7;Macrophages: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "classical monocyte: 1.4;intermediate monocyte: 1.4;myeloid DC: 1.2" "Group enriched" "Detected in many" 4 "dendritic cells: 1.2;monocytes: 1.4" "Cell line enriched" "Detected in single" 14 "THP-1: 3.3" "CAB032436, CAB033831" Supported "Intracellular and membrane" NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB032436: AB_639039, CAB033831: AB_1121347" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (5.36e-3)" "unprognostic (1.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-2)" "unprognostic (3.83e-2)" "unprognostic (2.10e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (6.17e-2)" "unprognostic (1.09e-1)" 34.2 3.9 0.3 8.6 0.6 0.4 4.4 1.3 3.0 4.0 5.7 10.5 14.3 1.4 1.0 4.8 2.5 8.6 4.5 0.3 0.7 2.1 3.3 4.9 18.1 1.0 0.6 1.0 1.0 0.8 0.7 22.8 0.8 0.8 13.9 0.1 2.1 1.9 0.9 1.4 19.3 10.6 0.9 2.4 4.1 2.1 0.6 5.4 1.4 1.5 2.3 20.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 1.4 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.4 0.3 0.6 1.3 3.0 0.3 0.7 1.0 0.6 0.8 0.9 0.6 0.8 0.3 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 15.6 14.7 0.3 0.0 12.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.1 CDC16 "ANAPC6, APC6, CUT9" ENSG00000130177 "Cell division cycle 16" Q13042 13 114234887-114272723 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042826 Approved NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA042826: AB_10793987" "unprognostic (7.32e-2)" "unprognostic (1.43e-2)" "unprognostic (2.05e-1)" "unprognostic (1.18e-3)" "unprognostic (1.50e-1)" "unprognostic (7.19e-3)" "unprognostic (6.82e-3)" "unprognostic (9.86e-2)" "unprognostic (7.64e-2)" "unprognostic (4.07e-1)" "unprognostic (1.27e-2)" "unprognostic (1.08e-2)" "unprognostic (1.99e-3)" "unprognostic (2.48e-1)" "unprognostic (1.42e-1)" "unprognostic (1.11e-3)" "unprognostic (1.51e-2)" 37.6 36.6 51.2 24.7 52.2 25.7 38.9 51.9 69.2 44.3 56.7 37.0 26.7 37.4 50.3 33.1 45.4 23.9 34.2 51.6 52.9 37.8 49.8 31.7 35.5 52.9 53.5 41.5 48.0 33.4 39.4 34.8 53.7 38.9 37.6 42.8 31.6 31.9 41.7 41.9 35.2 39.2 52.2 44.3 38.1 42.0 51.8 42.8 35.3 37.5 39.5 37.4 35.9 55.6 75.4 42.1 63.1 65.8 78.5 98.7 36.0 76.3 63.0 78.7 75.6 38.9 60.7 68.0 28.7 104.8 75.4 41.6 56.6 72.5 104.2 42.7 65.9 56.8 53.7 39.8 83.8 104.6 76.4 72.2 78.5 53.7 69.0 77.8 76.8 35.7 48.7 26.1 109.7 34.6 45.7 49.2 71.1 129.0 38.8 22.2 32.6 41.3 94.0 50.9 61.2 58.8 42.3 68.8 130.0 106.8 53.3 126.0 61.7 34.8 61.4 27.8 46.6 38.2 32.3 72.2 83.3 63.0 47.5 2.3 2.9 3.3 3.3 3.2 3.1 8.4 2.3 4.3 4.4 6.8 2.5 2.7 0.7 11.2 2.6 6.1 4.7 2.2 51.2 52.2 51.9 69.2 51.6 52.9 52.9 53.5 53.7 52.2 51.8 55.6 27.2 38.5 30.3 69.2 24.7 17.8 21.7 23.0 17.1 17.1 20.4 20.7 37.4 24.3 39.7 35.0 25.0 38.1 24.0 13.6 23.5 34.4 34.6 63.3 25.9 27.1 19.7 45.0 41.6 37.2 33.8 33.5 30.1 31.3 26.6 30.4 28.2 32.6 34.7 13.5 39.3 31.0 16.2 22.0 12.9 29.1 26.4 24.9 23.2 23.4 27.3 23.0 19.6 45.8 65.3 33.0 12.9 29.0 24.9 26.2 19.2 28.7 71.0 23.3 26.3 31.6 23.5 53.9 49.5 21.4 19.0 24.9 21.8 31.3 23.8 18.0 CDC73 "C1orf28, FIHP, HRPT1, HRPT2, parafibromin" ENSG00000134371 "Cell division cycle 73" Q6P1J9 1 193121983-193254815 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002326, CAB016359, HPA069324" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "CAB016359: AB_628102, HPA002326: , HPA069324: " "unprognostic (4.41e-2)" "unprognostic (6.22e-2)" "unprognostic (1.90e-2)" "unprognostic (5.30e-2)" "unprognostic (2.88e-3)" "unprognostic (3.53e-2)" "unprognostic (2.48e-3)" "unprognostic (5.74e-2)" "unprognostic (1.25e-1)" "unprognostic (1.40e-1)" "unprognostic (7.23e-3)" "unprognostic (2.17e-1)" "unprognostic (5.44e-3)" "unprognostic (3.47e-1)" "unprognostic (2.49e-1)" "unprognostic (6.73e-3)" "unprognostic (2.98e-3)" 11.3 9.5 5.8 7.3 6.9 8.9 10.7 6.1 7.3 11.1 4.5 10.2 5.6 10.3 8.5 8.4 7.2 5.9 9.6 4.6 8.1 10.4 9.2 7.9 7.5 6.9 7.2 11.5 6.4 12.9 5.6 9.4 7.9 15.1 9.0 10.1 7.7 9.7 12.2 7.0 7.7 10.3 7.9 8.6 7.0 5.9 6.5 10.6 13.1 5.6 7.9 9.7 8.5 8.3 9.3 2.4 16.6 11.5 18.3 18.9 4.9 6.7 16.1 19.5 16.4 6.5 12.3 10.5 5.2 20.4 8.8 10.7 16.8 14.9 24.7 6.1 4.1 7.3 8.1 7.2 16.1 16.0 11.6 13.7 16.0 14.9 17.7 20.6 17.8 11.1 8.1 14.2 28.8 3.5 13.9 9.2 11.9 21.9 2.5 10.6 7.0 15.0 26.6 8.2 3.9 12.3 8.6 26.8 22.3 21.0 18.3 14.0 9.2 19.3 2.2 16.4 12.6 12.2 7.2 7.6 11.9 10.2 30.1 2.2 0.5 0.7 0.8 1.0 1.2 0.9 1.1 0.6 0.6 0.5 1.4 1.2 0.3 1.3 0.8 1.0 0.9 0.4 5.8 6.9 6.1 7.3 4.6 8.1 6.9 7.2 7.9 7.9 6.5 8.3 44.5 35.3 25.4 54.5 44.9 37.2 35.6 38.4 36.5 30.4 24.4 21.8 44.5 25.8 27.2 33.1 35.5 25.0 48.0 18.2 33.2 37.5 19.7 24.6 39.6 38.0 11.4 40.8 71.9 32.2 42.0 39.1 28.1 30.8 41.1 17.6 25.4 17.2 31.6 21.9 76.4 15.8 34.6 27.4 49.1 8.5 33.5 38.3 28.4 54.4 46.0 35.2 41.2 78.4 112.3 35.5 16.9 36.1 50.3 34.9 19.2 36.3 20.6 36.7 26.3 49.0 48.3 55.6 33.0 36.8 34.9 38.0 44.4 30.3 18.6 27.9 CDK20 "CCRK, p42" ENSG00000156345 "Cyclin dependent kinase 20" Q8IZL9 9 87966441-87974753 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 21.9;Spermatocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.6" "Group enriched" "Detected in many" 7 "NK-cells: 3.6;T-cells: 2.3" "Cell line enhanced" "Detected in many" "SCLC-21H: 18.2;THP-1: 29.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007666, HPA027379, HPA027401" Enhanced Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA007666: AB_10600002, HPA027379: AB_10599939, HPA027401: AB_10601553" "unprognostic (4.60e-2)" "unprognostic (6.48e-2)" "unprognostic (1.69e-2)" "prognostic favorable (2.59e-4)" "unprognostic (2.32e-1)" "unprognostic (4.33e-3)" "unprognostic (2.81e-4)" "unprognostic (6.33e-2)" "unprognostic (1.45e-1)" "unprognostic (1.34e-1)" "unprognostic (2.83e-3)" "unprognostic (4.04e-2)" "prognostic favorable (2.12e-5)" "unprognostic (8.24e-3)" "unprognostic (5.77e-2)" "unprognostic (3.83e-2)" "unprognostic (1.42e-2)" 2.9 14.8 8.8 1.5 9.8 1.0 3.1 5.5 9.5 7.2 11.1 6.4 3.5 5.7 3.8 2.3 13.3 3.5 3.4 10.0 10.6 8.3 3.3 3.0 1.2 6.4 6.8 7.8 6.1 8.4 12.7 1.8 6.9 5.2 2.2 8.4 3.3 5.5 1.0 3.3 4.8 3.6 6.1 1.4 4.4 15.9 10.9 1.3 5.3 1.3 0.5 7.6 3.7 7.1 3.1 3.6 3.2 9.5 2.6 3.5 1.2 2.7 5.4 7.7 6.9 1.1 4.6 0.0 3.7 4.6 13.0 3.7 0.0 2.8 3.2 7.3 3.2 0.0 1.9 0.0 9.2 3.7 4.4 2.6 5.5 12.0 5.1 5.9 0.0 6.7 0.4 0.0 2.2 9.1 2.2 1.2 2.4 7.2 1.1 0.0 0.0 0.1 9.6 2.8 18.2 5.2 2.9 3.9 4.9 1.1 3.9 29.8 0.0 3.4 1.3 0.6 3.0 4.2 4.6 0.0 11.7 2.4 3.5 0.0 0.3 0.2 0.6 0.4 0.3 0.0 1.4 1.0 0.3 0.0 2.3 1.6 0.0 3.6 0.3 0.3 1.5 0.6 8.8 9.8 5.5 9.5 10.0 10.6 6.4 6.8 6.9 6.1 10.9 7.1 0.3 3.2 4.4 5.2 0.2 2.2 2.3 2.2 5.7 6.1 3.0 3.2 2.0 2.8 4.0 1.8 2.1 4.6 0.8 5.8 1.9 5.2 6.3 15.8 6.7 0.8 0.0 0.8 8.3 1.5 2.3 3.4 4.1 5.8 1.3 4.0 0.7 0.8 0.9 8.4 6.7 2.8 4.1 0.0 0.2 4.3 4.4 1.1 0.0 1.0 0.3 5.0 2.1 3.0 2.9 1.4 1.6 6.8 0.3 3.0 7.3 6.3 21.9 15.0 6.6 1.1 3.2 30.2 3.4 0.8 2.3 4.0 1.1 11.6 3.4 1.2 CEBPA "C/EBP-alpha, CEBP" ENSG00000245848 "CCAAT enhancer binding protein alpha" P49715 19 33299934-33302534 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 98.7;liver: 194.7;skin 1: 118.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.6;Hepatocytes: 106.5;Hofbauer cells: 87.0;Suprabasal keratinocytes: 171.8;Syncytiotrophoblasts: 212.3" "Cancer enhanced" "Detected in all" "liver cancer: 70.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 16.0;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 15 "dendritic cells: 5.1;granulocytes: 16.0;monocytes: 15.7" "Cell line enhanced" "Detected in many" "BEWO: 196.9;Hep G2: 110.9;NB-4: 114.1;THP-1: 407.7;U-937: 130.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052734, HPA065037, HPA067937" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA052734: AB_2681931, HPA065037: AB_2685410, HPA067937: AB_2685927" "unprognostic (1.80e-1)" "unprognostic (7.62e-3)" "unprognostic (2.09e-3)" "unprognostic (2.21e-2)" "unprognostic (3.38e-1)" "unprognostic (3.99e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-3)" "unprognostic (5.95e-2)" "unprognostic (3.96e-2)" "unprognostic (3.09e-1)" "unprognostic (9.45e-2)" "unprognostic (8.02e-3)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (2.72e-2)" 98.7 2.9 16.2 5.7 17.9 22.6 67.7 18.3 26.9 8.7 10.4 21.0 21.2 2.9 0.8 20.9 4.3 3.0 2.8 15.7 18.8 3.6 194.7 25.5 9.1 27.4 22.4 1.3 9.7 26.8 2.6 16.0 21.3 8.8 11.5 0.6 9.8 3.4 19.1 118.7 20.8 2.5 25.7 7.7 12.5 1.0 24.5 4.1 6.5 4.5 6.3 8.7 14.8 34.8 2.5 5.1 0.1 7.1 55.8 0.0 196.9 0.1 1.5 0.1 0.0 24.8 0.1 0.0 3.0 0.0 1.1 9.4 5.8 0.6 0.0 35.8 7.2 0.1 0.1 110.9 0.9 36.6 42.1 2.2 25.4 0.0 0.2 0.0 0.0 2.8 2.4 0.0 0.0 12.7 0.2 114.1 5.0 61.8 2.7 0.0 0.4 1.1 0.2 17.7 0.4 1.7 0.7 0.5 0.8 6.2 13.7 407.7 0.1 0.1 0.8 0.1 0.9 0.4 0.0 0.2 0.0 130.9 0.0 16.0 7.1 0.0 0.8 12.3 0.7 0.0 0.1 0.5 5.1 0.1 0.2 0.4 2.5 0.0 15.7 0.2 0.0 2.1 16.2 17.9 18.3 26.9 15.7 18.8 27.4 22.4 21.3 25.7 24.5 34.8 5.4 16.0 37.8 0.0 2.8 37.3 20.8 3.3 22.2 0.7 6.2 12.2 0.4 57.2 5.1 0.0 0.0 40.3 14.4 91.6 3.9 0.5 0.0 0.8 0.8 4.9 4.2 5.7 1.9 5.8 44.3 9.5 12.8 1.3 1.3 0.0 2.2 106.5 87.0 0.0 0.3 24.8 4.1 35.0 27.4 0.2 3.1 42.9 5.4 17.8 28.2 8.4 6.2 1.0 0.4 1.9 30.6 1.5 2.0 15.1 42.5 4.9 5.1 0.5 0.0 4.1 3.1 0.2 0.7 29.7 171.8 212.3 5.0 0.3 51.5 12.2 CFAP92 "FAP92, FLJ43738, KIAA1257" ENSG00000114656 "Cilia and flagella associated protein 92 (putative)" Q9ULG3 3 128909866-129002690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 22.1" "Group enriched" "Detected in some" 4 "Adipocytes: 1.3;Cardiomyocytes: 1.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "neutrophil: 34.0" "Lineage enriched" "Detected in single" 48 "granulocytes: 34.0" "Cell line enhanced" "Detected in many" "AF22: 7.6;HL-60: 13.5;THP-1: 9.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042811, HPA048445" Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA042811: AB_2678180, HPA048445: AB_2680397" "unprognostic (4.17e-2)" "unprognostic (5.16e-2)" "unprognostic (2.46e-1)" "unprognostic (2.67e-1)" "unprognostic (9.41e-3)" "unprognostic (2.45e-1)" "unprognostic (6.74e-2)" "unprognostic (4.22e-2)" "unprognostic (6.48e-3)" "unprognostic (7.45e-2)" "unprognostic (1.72e-1)" "unprognostic (2.88e-2)" "unprognostic (1.42e-2)" "unprognostic (3.38e-1)" "unprognostic (4.69e-2)" "unprognostic (2.52e-1)" "unprognostic (5.50e-2)" 0.4 0.6 3.1 1.0 2.1 2.1 0.8 3.9 2.2 0.4 4.4 0.7 0.8 0.7 0.5 1.1 3.3 1.4 0.6 3.7 2.5 0.5 0.2 1.1 1.0 3.1 4.7 1.2 0.9 1.7 1.8 1.1 3.2 1.0 0.8 2.7 0.7 0.3 0.7 4.3 0.9 0.2 1.4 1.0 1.1 22.1 3.3 4.2 0.8 0.5 0.3 0.4 0.1 1.3 1.0 1.4 7.6 1.6 0.1 0.2 2.4 0.3 0.3 0.1 0.0 1.2 1.0 1.5 0.3 0.0 0.7 1.1 2.3 0.1 0.0 0.6 1.1 3.3 1.9 1.0 0.0 13.5 0.7 0.0 1.4 0.0 0.1 0.5 0.1 2.9 0.9 1.7 0.2 1.5 1.3 2.5 1.4 2.6 1.4 1.1 0.8 0.9 0.0 1.5 1.5 0.7 0.4 0.5 0.6 1.0 2.6 9.2 0.4 0.8 1.2 0.8 0.5 2.2 2.0 2.5 0.6 5.0 0.6 0.8 0.7 2.9 0.3 0.3 0.2 0.4 0.2 0.2 0.2 0.3 0.3 0.5 34.0 0.3 0.3 0.3 0.2 0.2 3.1 2.1 3.9 2.2 3.7 2.5 3.1 4.7 3.2 1.4 3.3 1.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859664-863641 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1496.7;breast: 993.2" "Group enriched" "Detected in many" 6 "Fibroblasts: 9365.5;Leydig cells: 5032.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 297.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.6" "Group enriched" "Detected in many" 5 "ASC diff: 197.4;THP-1: 342.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 732000000 4400000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favorable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 1496.7 33.3 1.5 9.6 1.6 10.7 993.2 1.2 2.4 597.4 3.7 324.8 23.5 58.4 2.4 212.8 258.0 9.6 854.2 1.7 2.3 18.1 8.7 363.3 2.1 3.3 2.3 74.3 41.4 1.7 9.0 14.5 3.6 277.8 10.9 0.6 247.3 6.3 197.0 488.6 248.4 4.0 2.6 28.6 263.8 51.8 2.9 3.6 332.3 26.9 0.8 848.3 729.8 5.8 3.9 5.2 0.6 2.2 197.4 26.2 9.5 0.8 0.0 0.0 0.0 0.8 0.4 0.2 5.7 0.0 0.5 3.0 1.8 0.5 0.0 5.7 14.5 0.5 12.3 3.8 3.6 2.5 4.9 8.7 0.2 0.1 0.0 0.8 0.0 4.5 11.9 0.9 0.0 2.6 0.6 49.2 1.0 4.5 16.1 1.3 0.5 5.2 0.3 1.2 1.8 1.8 5.5 1.9 0.5 0.6 7.5 342.2 0.4 0.2 5.1 2.9 0.6 7.8 4.7 0.4 0.2 20.8 0.2 297.6 41.2 127.8 8.4 55.5 13.2 5.7 4.2 10.2 14.5 1.4 9.7 9.7 112.0 1.3 57.3 1.8 4.7 37.8 1.5 1.6 1.2 2.4 1.7 2.3 3.3 2.3 3.6 2.6 2.9 5.8 857.8 9.6 23.3 0.0 19.2 785.5 49.0 10.1 17.1 2.9 107.3 120.1 55.5 21.5 30.9 18.4 2.1 36.6 40.0 33.1 11.7 7.7 27.1 23.1 593.3 114.8 4.2 8.2 0.2 0.0 32.9 9365.5 113.6 15.9 17.1 0.9 30.4 2.6 272.4 1.7 0.4 8.7 0.0 424.7 1145.2 89.6 5032.4 442.5 642.1 4.7 303.6 1.3 21.6 0.0 0.1 2.9 64.8 283.2 41.0 19.7 4.3 3.4 28.4 6.5 0.0 414.3 530.2 11.4 21.3 28.6 735.9 34.3 82.8 1.2 21.0 233.2 CHI3L1 "GP39, YK-40, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186704 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 232.4;brain: 239.4;liver: 447.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 88.7;Ductal cells: 88.9;Hepatocytes: 61.8;Hofbauer cells: 317.5" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 495 "neutrophil: 470.4" "Lineage enriched" "Detected in single" 495 "granulocytes: 470.4" "Cell line enhanced" "Detected in some" "ASC diff: 322.9;ASC TERT1: 712.9;HSkMC: 637.0;THP-1: 1068.4;U-138 MG: 303.5;U-87 MG: 303.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 10 "olfactory bulb: 16.0" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 25100000 180000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" 79.8 2.0 58.9 138.9 75.9 232.4 62.8 55.3 94.7 30.5 56.8 6.5 0.4 19.5 1.0 14.4 23.4 3.0 9.8 47.4 129.6 60.9 447.8 38.4 32.4 239.4 112.8 6.6 13.8 0.2 134.5 10.1 135.6 13.7 2.0 50.9 99.4 0.9 21.0 75.6 16.8 6.8 70.0 13.9 9.7 1.0 156.4 12.4 15.0 1.0 36.9 97.8 9.1 70.8 0.8 0.0 0.0 0.3 322.9 712.9 0.0 0.0 0.2 0.0 0.0 75.3 0.2 0.1 1.2 0.4 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 8.3 0.3 0.3 637.0 0.0 1.9 0.3 30.8 0.0 0.0 0.0 1.0 0.2 0.3 0.0 5.8 2.7 0.0 0.0 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.3 0.5 0.4 0.2 0.0 1068.4 0.0 303.5 1.6 0.0 0.4 2.3 41.9 0.3 303.7 1.2 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 470.4 0.0 0.9 0.0 0.0 1.3 58.9 75.9 55.3 94.7 47.4 129.6 239.4 112.8 135.6 70.0 156.4 70.8 0.7 6.4 42.8 20.5 0.1 4.2 47.1 88.7 0.0 0.1 29.8 21.5 1.0 2.8 17.3 27.6 0.0 1.3 0.6 0.0 0.0 88.9 0.0 4.8 2.2 2.1 0.0 0.4 1.1 0.0 1.1 18.6 0.0 7.2 0.0 0.0 0.0 61.8 317.5 0.0 0.1 0.0 6.1 0.8 0.4 0.0 0.9 23.7 14.2 0.0 1.0 45.1 0.0 0.0 0.1 2.0 0.0 0.0 1.4 4.2 0.0 0.2 3.4 2.8 0.0 1.0 2.3 0.0 0.0 1.5 1.1 0.8 0.9 0.0 0.0 2.2 CHTOP "C1orf77, DKFZP547E1010, FOP, SRAG" ENSG00000160679 "Chromatin target of PRMT1" Q9Y3Y2 1 153633982-153646306 "Plasma proteins, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028647, HPA030540" Approved Enhanced "Nuclear speckles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA028647: AB_10602699, HPA030540: AB_2673516" "unprognostic (2.72e-1)" "unprognostic (2.41e-1)" "unprognostic (3.41e-2)" "unprognostic (6.77e-2)" "unprognostic (6.80e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (8.65e-2)" "prognostic unfavorable (4.08e-4)" "unprognostic (9.16e-2)" "unprognostic (2.20e-1)" "unprognostic (7.30e-3)" "prognostic unfavorable (2.02e-4)" "unprognostic (1.58e-2)" "unprognostic (4.19e-2)" "unprognostic (2.70e-1)" "prognostic favorable (2.69e-4)" 42.4 44.8 48.1 36.5 54.1 62.5 44.2 54.7 56.0 52.5 48.3 44.2 30.3 45.2 36.2 50.3 47.5 21.9 63.3 47.8 51.1 66.5 54.8 39.3 46.6 51.9 50.7 55.2 63.4 35.9 48.7 33.4 52.2 48.4 32.7 59.9 44.4 29.6 124.4 52.6 46.8 30.5 50.0 65.4 47.9 37.6 49.6 65.7 55.8 68.4 44.4 45.1 47.9 63.5 74.3 63.9 106.2 65.0 45.2 33.1 84.3 51.2 47.0 71.3 61.2 71.6 72.9 83.5 75.6 48.0 46.6 66.8 103.4 74.7 46.9 97.8 95.7 65.5 102.2 60.0 56.1 101.8 78.8 38.5 84.8 69.0 97.5 59.2 57.7 89.4 82.1 62.2 54.1 94.3 109.8 102.6 123.6 106.9 79.1 67.5 65.0 92.5 69.8 100.5 64.3 74.5 54.6 77.8 91.6 69.9 83.7 138.6 50.0 47.7 70.4 60.7 83.8 86.2 77.8 95.5 50.1 81.9 56.8 84.9 42.9 40.9 46.0 44.8 46.2 46.2 45.3 45.3 54.4 43.3 45.2 41.0 30.8 35.1 43.0 41.7 51.9 46.4 48.1 54.1 54.7 56.0 47.8 51.1 51.9 50.7 52.2 50.0 49.6 63.5 46.4 32.1 37.3 32.3 50.1 63.0 103.6 59.7 37.5 40.8 45.6 33.5 74.1 57.2 43.5 53.3 33.3 91.7 47.7 49.2 50.9 69.5 34.9 50.6 42.6 54.2 60.3 81.9 16.1 64.8 121.9 47.1 42.3 63.4 46.3 59.7 43.9 41.2 69.7 43.7 17.6 56.4 42.7 48.9 38.2 18.0 44.7 40.9 35.6 14.0 69.3 44.0 52.5 16.6 40.1 61.3 58.1 42.2 48.2 101.8 48.4 49.0 33.2 57.5 19.7 34.9 59.7 125.2 115.2 46.5 61.7 128.6 45.7 57.9 52.3 110.2 CITED4 ENSG00000179862 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4" Q96RK1 1 40861054-40862363 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 172.1;Breast glandular cells: 183.7;Breast myoepithelial cells: 225.0;Cholangiocytes: 258.7;Endometrial ciliated cells: 350.4;Glandular and luminal cells: 202.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 91.3;THP-1: 264.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056434 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Vesicles "HPA056434: AB_2683132" "unprognostic (5.39e-3)" "unprognostic (5.41e-2)" "unprognostic (1.53e-1)" "prognostic favorable (4.38e-5)" "unprognostic (3.43e-3)" "unprognostic (1.90e-2)" "unprognostic (3.44e-3)" "unprognostic (3.42e-2)" "unprognostic (2.67e-1)" "unprognostic (1.98e-3)" "unprognostic (2.25e-2)" "unprognostic (6.00e-2)" "unprognostic (2.29e-3)" "unprognostic (2.10e-1)" "unprognostic (2.11e-1)" "unprognostic (2.11e-1)" "unprognostic (6.13e-2)" 13.7 15.1 9.3 1.1 10.6 19.1 30.3 9.4 9.5 18.0 4.3 28.9 1.6 17.1 2.4 29.0 14.4 1.9 26.6 6.6 14.5 20.4 38.8 11.4 1.7 14.6 15.4 10.3 49.1 4.4 4.9 1.7 10.6 16.4 0.4 0.8 34.2 8.5 33.0 51.5 7.7 2.3 12.0 29.9 13.4 25.4 13.1 1.2 7.3 9.2 1.3 8.9 23.7 10.5 29.5 5.7 1.6 34.6 0.7 1.3 34.4 1.9 2.1 0.7 0.8 3.0 38.5 0.1 4.6 0.5 1.0 44.6 2.4 24.0 0.6 0.1 0.4 0.2 3.3 4.9 5.9 1.0 0.4 4.2 10.1 2.3 7.6 2.8 1.8 0.4 0.1 0.1 1.3 0.9 0.5 19.6 11.1 0.9 3.9 0.3 0.0 0.1 91.3 16.9 6.7 1.9 1.4 35.8 2.0 3.7 17.4 264.9 2.3 0.0 0.0 0.4 1.1 0.0 0.8 0.0 0.0 13.8 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 9.3 10.6 9.4 9.5 6.6 14.5 14.6 15.4 10.6 12.0 13.1 10.5 17.4 9.6 1.1 1.3 4.0 19.1 172.1 2.1 37.0 4.0 183.7 225.0 10.4 258.7 3.5 22.0 0.0 1.0 11.9 3.7 43.0 14.2 47.9 350.4 24.4 48.9 7.7 9.7 2.0 43.6 0.9 14.0 17.9 202.6 0.0 30.5 11.4 43.1 1.3 1.7 1.7 4.8 2.0 10.4 3.2 64.8 5.0 13.7 19.6 1.0 4.6 46.1 2.1 2.0 3.8 33.0 3.4 5.7 2.4 65.6 0.2 88.0 6.5 3.0 19.7 72.2 19.7 0.9 1.5 49.9 24.3 0.1 14.6 37.3 3.6 122.3 CMYA5 "C5orf10, DKFZp451G223, SPRYD2, TRIM76" ENSG00000164309 "Cardiomyopathy associated 5" Q8N3K9 5 79689836-79800240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 623.5;tongue: 799.5" "Cell type enriched" "Detected in many" 15 "Cardiomyocytes: 3425.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 1.3;RT4: 1.5;THP-1: 5.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA074081, HPA077831" Enhanced Approved "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles, Cytosol" "Vesicles, Plasma membrane" "HPA074081: , HPA077831: " "unprognostic (5.53e-2)" "unprognostic (9.91e-3)" "unprognostic (1.21e-2)" "unprognostic (1.49e-2)" "unprognostic (9.01e-4)" "unprognostic (7.00e-2)" "unprognostic (7.39e-2)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.75e-1)" "unprognostic (5.04e-1)" "unprognostic (1.93e-1)" "unprognostic (1.93e-2)" "unprognostic (6.30e-3)" "unprognostic (3.88e-2)" "unprognostic (7.69e-2)" "unprognostic (9.74e-2)" 0.9 0.1 1.4 0.2 1.4 0.0 3.9 1.2 2.1 1.7 3.1 1.3 0.1 5.9 4.6 6.6 2.1 0.9 155.8 0.6 0.6 2.5 1.2 0.5 0.0 1.6 2.0 14.6 0.3 3.6 2.0 1.1 1.1 6.1 0.2 1.7 6.1 2.1 623.5 2.2 0.4 4.6 1.1 0.0 0.6 0.5 1.7 0.9 2.3 799.5 0.1 2.1 1.2 0.8 0.0 0.0 0.0 0.1 0.5 0.4 0.6 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 1.0 5.4 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.4 1.2 2.1 0.6 0.6 1.6 2.0 1.1 1.1 1.7 0.8 2.7 9.6 2.8 69.5 0.4 1.3 17.9 2.9 4.6 2.0 24.4 46.6 3425.2 5.7 12.2 25.8 0.0 21.4 1.3 0.4 17.6 0.7 0.3 29.3 7.2 19.7 1.8 0.0 32.9 0.4 2.9 113.7 3.6 55.2 1.3 2.5 0.4 2.3 2.1 217.0 10.7 0.2 8.2 0.6 1.6 2.3 14.9 1.4 0.0 6.5 0.1 8.8 2.1 156.3 2.9 0.6 0.2 13.5 0.6 4.8 0.0 15.4 6.2 3.0 0.0 165.6 23.1 2.5 2.0 2.2 5.4 32.8 1.2 1.7 0.2 18.1 CNPY2 "HP10390, TMEM4, ZSIG9" ENSG00000257727 "Canopy FGF signaling regulator 2" Q9Y2B0 12 56309842-56316119 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 475.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038465, HPA038466" Supported Supported Cytosol "Intracellular and membrane" NA NA 220000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA038465: AB_10967609, HPA038466: AB_10672646" "unprognostic (3.83e-2)" "unprognostic (5.62e-2)" "unprognostic (2.49e-1)" "unprognostic (2.46e-2)" "unprognostic (4.33e-2)" "unprognostic (2.20e-1)" "unprognostic (1.17e-3)" "unprognostic (1.46e-1)" "unprognostic (7.68e-2)" "unprognostic (2.04e-3)" "prognostic favorable (8.37e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (2.32e-8)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "unprognostic (2.67e-2)" "unprognostic (5.06e-2)" 36.7 52.5 28.4 25.8 30.3 24.7 41.8 30.0 30.7 43.3 38.1 36.6 30.9 35.6 74.4 34.1 38.1 25.4 28.4 27.7 31.8 37.8 75.7 30.5 22.0 31.1 29.0 42.7 58.9 47.3 66.8 40.8 28.9 35.3 38.5 18.8 53.1 36.4 21.2 23.5 34.6 24.9 30.5 35.1 42.1 20.0 29.8 27.0 44.7 18.6 26.6 32.9 31.1 32.2 50.6 75.5 76.0 62.8 186.0 64.0 120.7 51.0 117.4 108.7 76.5 116.0 87.9 51.2 95.0 132.4 53.2 72.4 92.3 62.8 68.7 51.3 57.5 49.9 106.1 121.8 83.6 94.9 60.4 76.5 80.5 89.9 106.6 165.5 91.1 59.0 73.8 113.5 81.3 76.2 58.2 105.3 72.6 107.5 109.5 65.1 58.3 84.9 90.1 47.6 67.9 41.7 85.1 86.8 93.6 92.7 78.0 176.8 41.2 42.7 33.6 52.2 74.7 58.4 88.2 41.5 90.2 88.2 70.9 56.8 66.5 36.8 65.8 56.9 77.8 73.2 70.7 71.7 69.5 66.2 70.4 67.0 9.8 70.9 34.6 71.3 68.4 76.4 28.4 30.3 30.0 30.7 27.7 31.8 31.1 29.0 28.9 30.5 29.8 32.2 76.2 48.1 93.7 17.3 79.2 54.8 75.2 129.9 17.1 80.5 178.6 191.6 9.8 140.2 95.2 101.2 64.6 248.3 74.0 80.2 52.8 191.8 40.2 54.7 59.9 72.6 141.9 34.3 31.8 168.7 475.0 77.5 31.1 53.1 91.3 60.7 98.9 185.8 147.4 58.9 32.4 187.2 103.7 59.2 55.8 17.7 103.8 47.8 122.7 13.1 99.7 88.6 125.7 40.2 45.6 162.4 114.1 100.1 68.2 107.4 176.6 145.5 74.1 92.2 26.3 59.1 82.8 72.4 44.0 20.0 53.8 236.4 60.5 78.2 177.8 71.0 COMMD2 HSPC042 ENSG00000114744 "COMM domain containing 2" Q86X83 3 149738472-149752495 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044190 Uncertain NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 5: Breast - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA044190: AB_10966289" "unprognostic (2.17e-1)" "unprognostic (8.34e-3)" "unprognostic (6.28e-2)" "unprognostic (1.55e-3)" "unprognostic (1.53e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.78e-4)" "unprognostic (1.45e-1)" "unprognostic (1.02e-2)" "unprognostic (4.93e-2)" "prognostic unfavorable (3.69e-6)" "unprognostic (1.31e-1)" "unprognostic (4.03e-3)" "unprognostic (1.76e-1)" "unprognostic (1.89e-1)" "unprognostic (6.25e-2)" "unprognostic (4.86e-2)" 8.6 7.4 8.5 7.5 9.4 8.9 15.2 9.3 10.6 11.6 8.3 7.3 7.9 13.4 7.3 8.9 8.2 7.7 8.5 8.4 8.5 10.5 9.1 12.6 10.8 9.0 9.0 12.4 6.4 10.3 4.3 13.8 9.0 9.3 8.4 10.6 8.4 8.4 6.4 9.6 6.7 12.3 9.0 10.1 7.2 5.2 8.9 12.3 14.0 8.0 10.4 7.5 7.4 10.2 27.4 7.8 25.2 14.7 21.6 24.7 16.6 16.8 17.6 25.6 25.6 13.9 16.6 22.0 18.6 16.5 16.0 17.1 24.4 20.6 29.7 16.2 22.9 19.8 9.8 9.4 22.9 28.6 8.6 18.8 22.3 12.7 22.5 17.3 18.3 13.6 9.8 12.0 18.5 8.6 20.0 14.0 27.9 16.6 10.4 18.2 25.6 29.6 24.5 7.2 11.5 17.6 19.7 15.6 37.0 20.0 28.9 18.7 16.0 14.9 5.9 15.1 20.2 21.5 9.0 35.8 14.6 25.5 6.3 16.9 6.3 11.2 5.8 9.6 8.5 6.6 7.1 7.1 8.0 6.1 7.4 7.9 4.7 9.7 12.5 4.9 6.3 7.3 8.5 9.4 9.3 10.6 8.4 8.5 9.0 9.0 9.0 9.0 8.9 10.2 48.5 64.1 25.7 11.8 41.8 20.9 37.0 60.9 26.7 55.5 39.1 47.9 16.5 31.5 58.7 22.0 187.7 55.2 41.9 18.6 43.0 55.4 3.2 26.1 37.7 42.7 24.6 26.9 21.6 39.7 60.8 36.8 25.5 23.9 46.3 35.3 40.7 16.9 45.5 28.6 16.2 17.5 52.9 29.2 52.8 4.8 36.4 30.1 33.8 16.9 91.0 33.0 36.0 21.1 25.4 55.0 22.2 36.1 32.0 28.7 26.5 31.7 33.0 116.8 52.6 29.3 35.3 65.2 47.9 35.9 21.6 31.9 37.2 45.7 20.8 23.9 COX19 MGC104475 ENSG00000240230 "Cytochrome c oxidase assembly factor COX19" Q49B96 7 898778-975549 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021226 Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "HPA021226: AB_1847176" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (1.05e-2)" "unprognostic (3.76e-2)" "unprognostic (5.22e-2)" "unprognostic (1.05e-1)" "unprognostic (2.13e-2)" "unprognostic (1.61e-1)" "unprognostic (3.96e-1)" "unprognostic (5.60e-2)" "unprognostic (4.79e-2)" "unprognostic (3.36e-2)" "unprognostic (2.37e-3)" "unprognostic (2.49e-2)" "unprognostic (1.64e-1)" "unprognostic (2.74e-1)" "unprognostic (9.14e-3)" 4.5 12.3 4.0 3.2 4.7 6.7 4.4 6.3 4.8 5.4 2.2 6.8 5.3 4.8 2.2 5.8 6.8 2.0 5.2 4.0 4.3 6.2 5.9 4.9 4.4 4.8 4.2 5.5 7.5 6.4 5.9 2.7 5.0 6.2 3.5 2.9 6.0 2.8 7.5 8.0 7.4 2.4 3.6 7.6 5.9 4.0 4.4 3.7 5.6 4.9 3.5 5.0 4.8 6.9 13.9 3.7 4.1 5.2 3.1 4.4 7.8 6.1 4.4 5.2 4.3 9.6 7.6 6.8 2.0 3.7 8.2 9.1 4.3 4.2 4.1 2.1 7.2 3.0 4.5 7.1 9.8 7.3 6.8 5.1 9.7 4.0 9.2 5.8 3.3 6.9 9.0 5.7 3.4 9.0 3.1 8.6 10.6 16.3 8.6 7.4 0.9 3.3 4.6 6.0 5.4 5.4 3.5 14.4 12.0 6.7 7.2 17.1 4.2 5.2 7.6 6.0 9.5 7.1 5.2 6.6 4.6 10.4 8.7 9.4 5.2 8.3 5.8 5.1 5.9 6.6 6.1 5.2 4.5 6.1 7.5 7.2 5.0 5.4 5.5 7.9 5.9 4.4 4.0 4.7 6.3 4.8 4.0 4.3 4.8 4.2 5.0 3.6 4.4 6.9 25.4 12.8 21.4 6.2 35.4 24.6 35.9 37.7 19.4 19.3 21.7 19.2 14.2 31.5 24.1 31.3 12.5 27.8 49.7 29.9 15.6 34.9 7.4 58.4 23.8 23.5 44.9 17.2 13.1 34.0 41.8 19.0 17.3 49.3 34.9 28.1 25.0 31.0 26.1 15.2 13.3 32.6 36.7 24.9 28.5 2.7 19.6 29.4 21.4 13.1 46.6 33.3 64.9 6.6 22.7 49.6 31.7 14.3 20.8 36.8 37.7 25.8 36.2 27.0 6.6 18.7 23.2 19.2 32.7 21.4 25.7 41.9 39.5 30.9 32.2 45.3 CTSG CG ENSG00000100448 "Cathepsin G" P08311 14 24573518-24576250 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 154 "bone marrow: 5352.9" "Cell type enriched" "Detected in some" 16 "granulocytes: 534.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "THP-1: 8681.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000110, HPA047737" Enhanced "Intracellular and membrane" NA NA 330000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "CAB000110: , HPA047737: AB_2680140" "unprognostic (1.67e-1)" "unprognostic (2.57e-2)" "unprognostic (6.92e-2)" "unprognostic (1.08e-1)" "prognostic favorable (1.57e-4)" "unprognostic (4.05e-2)" "unprognostic (4.13e-2)" "unprognostic (3.06e-1)" "unprognostic (2.42e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" "unprognostic (1.63e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.91e-4)" 23.4 0.1 0.0 13.5 0.0 5352.9 25.4 0.0 0.0 16.6 0.0 25.5 5.8 9.6 10.2 22.1 2.7 25.9 3.7 0.0 0.0 2.3 3.6 11.6 6.5 0.0 0.0 0.5 3.5 1.5 1.0 2.9 0.0 3.7 25.5 0.0 11.5 4.8 1.8 28.0 18.1 7.7 0.0 16.9 4.9 3.2 0.0 26.0 0.8 7.6 6.0 34.8 4.1 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 303.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 33.2 0.0 0.1 0.0 0.0 3.6 41.5 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 1.2 0.0 3.6 0.0 0.0 8681.4 0.0 0.0 0.3 0.0 5.3 0.0 0.8 2.8 0.0 1287.5 0.1 0.0 6.0 0.0 1.1 1.0 0.0 0.0 0.9 3.4 5.4 0.0 0.0 1.7 7.3 5.0 0.0 6.5 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 12.8 33.3 0.0 0.2 6.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.3 0.0 0.0 2.4 0.0 1.3 0.0 0.0 0.1 1.0 0.0 0.0 534.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.6 11.1 9.1 0.0 1.5 5.4 0.0 1.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.7 0.0 0.0 0.2 1.3 0.3 1.7 0.0 4.0 0.0 5.1 0.0 0.4 0.0 CUL4A ENSG00000139842 "Cullin 4A" Q13619 13 113208193-113267108 "Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 171.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058979 Approved Nucleoplasm NA NA 44000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA058979: AB_2683868" "unprognostic (3.01e-1)" "unprognostic (5.93e-3)" "unprognostic (6.19e-2)" "unprognostic (7.51e-2)" "unprognostic (3.19e-1)" "unprognostic (2.53e-2)" "unprognostic (6.41e-3)" "unprognostic (6.77e-2)" "unprognostic (1.45e-1)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "unprognostic (5.16e-3)" "unprognostic (3.57e-3)" "prognostic favorable (2.84e-4)" "unprognostic (2.95e-1)" "unprognostic (3.91e-2)" "unprognostic (3.48e-1)" 39.3 34.6 17.0 26.0 19.4 63.3 34.3 19.2 17.2 30.9 29.7 33.0 26.9 30.8 24.2 36.9 29.1 24.4 63.1 16.2 20.2 30.3 40.5 30.8 33.0 23.2 21.0 28.6 36.6 33.9 25.3 30.2 21.9 33.6 29.8 21.0 37.1 25.1 171.7 47.7 31.4 25.3 19.4 31.4 34.2 47.2 19.5 26.1 31.5 125.7 31.1 32.2 32.4 23.2 106.9 50.9 50.7 43.9 60.2 67.0 65.5 104.9 79.0 88.9 68.5 93.0 85.8 129.7 44.7 92.7 87.3 67.4 76.9 58.3 82.4 57.2 77.1 85.8 109.3 74.8 72.1 134.2 56.8 48.1 70.3 52.5 82.2 59.3 60.3 47.8 88.2 24.8 89.7 51.4 67.7 123.3 47.9 149.3 53.5 70.9 52.2 59.7 61.5 47.8 73.7 43.5 54.3 118.6 53.9 43.6 84.6 141.7 83.2 42.7 90.0 47.2 59.9 65.3 49.8 113.0 93.7 108.2 69.0 12.9 20.0 18.1 27.6 29.1 25.7 17.1 27.1 31.2 17.4 16.5 23.5 27.9 5.9 16.2 30.4 13.5 19.9 25.8 17.0 19.4 19.2 17.2 16.2 20.2 23.2 21.0 21.9 19.4 19.5 23.2 27.8 28.9 36.1 46.7 28.2 46.4 30.9 24.9 52.9 14.4 35.5 27.2 140.3 31.5 24.4 35.0 10.4 32.3 25.0 29.2 25.4 28.3 61.6 28.7 28.0 30.0 23.9 73.8 46.1 37.2 40.5 33.0 36.7 41.7 11.4 26.1 23.6 56.9 30.4 28.6 41.0 34.2 24.4 40.9 30.5 118.2 35.8 31.0 39.2 37.5 28.5 13.0 28.8 43.2 66.1 39.8 25.3 31.6 38.0 54.0 22.2 26.9 26.4 18.1 32.9 30.5 30.9 65.3 38.1 53.8 60.0 39.7 32.5 25.2 32.3 45.6 DCAF12 "CT102, DKFZP434O125, KIAA1892, MGC1058, TCC52, WDR40A" ENSG00000198876 "DDB1 and CUL4 associated factor 12" Q5T6F0 9 34086387-34127399 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 165.9;Erythroid cells: 315.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062279 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA062279: AB_2684734" "unprognostic (9.56e-2)" "unprognostic (3.47e-2)" "unprognostic (3.92e-3)" "unprognostic (2.22e-2)" "unprognostic (6.61e-2)" "unprognostic (2.40e-1)" "unprognostic (6.34e-3)" "unprognostic (6.57e-2)" "unprognostic (2.86e-3)" "prognostic favorable (2.81e-5)" "unprognostic (1.77e-1)" "unprognostic (4.37e-1)" "unprognostic (2.21e-3)" "unprognostic (3.09e-2)" "unprognostic (2.85e-1)" "unprognostic (1.92e-2)" "unprognostic (1.03e-1)" 16.2 32.3 10.4 20.0 10.2 33.7 21.7 9.9 10.8 20.3 13.6 22.2 17.1 17.3 16.8 29.4 18.4 16.9 12.7 9.6 10.1 17.4 23.2 17.3 37.0 11.8 10.7 16.0 15.8 22.7 10.0 28.6 11.2 16.2 25.9 17.4 16.8 14.4 18.2 16.6 17.3 17.5 10.9 17.5 17.3 62.4 10.5 30.0 19.5 23.3 42.2 24.1 16.8 11.4 45.1 29.2 58.1 26.1 24.9 21.6 33.0 24.5 31.4 43.8 37.6 25.6 21.4 88.6 20.7 27.7 15.2 19.6 64.4 28.7 37.6 40.3 34.6 70.1 58.6 36.1 36.4 86.5 41.7 21.6 54.8 28.0 53.1 33.7 35.3 48.9 70.2 30.0 28.6 18.5 55.3 85.8 29.9 29.5 28.3 51.8 31.6 39.3 46.0 32.5 57.0 48.9 49.6 42.0 20.2 30.6 23.5 134.4 25.4 20.8 25.3 17.8 33.5 19.6 38.8 68.7 19.8 65.2 51.2 36.4 28.6 28.3 12.3 24.0 18.5 1.2 12.2 14.1 25.3 0.4 9.8 11.4 27.6 16.0 20.4 20.4 22.9 20.2 10.4 10.2 9.9 10.8 9.6 10.1 11.8 10.7 11.2 10.9 10.5 11.4 13.8 6.4 20.0 7.5 5.9 38.5 18.8 13.3 21.1 6.9 20.3 14.7 6.7 8.6 13.4 5.5 6.2 21.5 27.6 22.0 25.4 16.0 165.9 27.3 13.7 18.2 25.2 315.8 10.0 18.2 25.2 14.5 16.3 19.3 17.7 20.6 15.0 21.9 31.4 10.1 10.4 22.3 10.2 63.9 16.2 63.0 20.2 32.1 17.8 12.2 22.4 7.5 11.3 11.6 8.8 18.0 15.7 21.1 29.6 28.6 13.1 21.5 23.4 7.0 13.1 13.8 17.5 40.1 43.2 33.1 38.6 22.4 16.7 30.0 19.6 38.4 DCANP1 "C5orf20, DCNP1" ENSG00000251380 "Dendritic cell associated nuclear protein" Q8TF63 5 135444214-135447348 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "Microglial cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "THP-1: 1.8" HPA048308 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Nuclear bodies" "HPA048308: AB_2680349" 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFA4 "DEF4, HP-4" ENSG00000164821 "Defensin alpha 4" P12838 8 6935820-6938306 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "bone marrow: 2702.9" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Hepatocytes: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 13 "neutrophil: 13.1" "Lineage enriched" "Detected in many" 13 "granulocytes: 13.1" "Cell line enriched" "Detected in single" 8 "THP-1: 6.8" HPA051266 Enhanced "Secreted to blood" NA NA 98000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA051266: AB_2681414" 0.7 0.1 0.0 0.2 0.0 2702.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.3 2.7 14.2 0.6 0.0 0.0 0.0 0.1 0.0 0.7 1.1 0.0 0.0 0.0 0.0 2.3 0.0 0.4 2.0 0.1 0.0 0.0 46.4 0.1 0.1 0.0 8.9 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 DHRS9 "3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4" ENSG00000073737 "Dehydrogenase/reductase 9" Q9BPW9 2 169064789-169096167 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.9;intestine: 70.4" "Cell type enhanced" "Detected in many" "Club cells: 229.3;Distal enterocytes: 261.2;Early spermatids: 153.2;Paneth cells: 299.9;Respiratory ciliated cells: 155.9;Syncytiotrophoblasts: 267.5;Urothelial cells: 249.2" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 258.3;eosinophil: 99.2;neutrophil: 77.3" "Lineage enriched" "Detected in many" 10 "granulocytes: 258.3" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 22.8;HUVEC TERT2: 21.5;NB-4: 33.7;THP-1: 98.0;TIME: 49.9;U-2197: 31.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036491, HPA036667" Approved "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036491: AB_10673498, HPA036667: AB_10670237" "unprognostic (1.15e-1)" "unprognostic (3.82e-3)" "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (4.80e-2)" "unprognostic (2.35e-1)" "unprognostic (3.24e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (3.62e-4)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.72e-1)" "unprognostic (3.23e-1)" "unprognostic (1.85e-2)" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-1)" 10.0 0.2 2.2 12.5 2.4 8.5 5.1 3.0 2.6 8.6 1.6 70.4 1.9 1.2 0.9 28.2 1.0 5.7 53.9 2.5 2.3 0.3 3.1 7.1 20.2 4.2 3.2 0.7 0.4 0.2 0.4 2.8 4.3 0.8 46.2 1.2 6.1 0.5 0.3 3.3 5.7 4.2 3.8 7.6 10.8 11.3 3.2 2.2 0.3 0.8 26.8 17.5 10.1 4.5 0.0 0.7 0.0 0.0 2.5 10.2 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.0 6.5 1.7 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 8.9 1.0 0.4 0.5 1.3 6.1 22.8 21.5 0.0 1.0 0.0 0.0 0.0 0.1 33.7 0.0 0.3 8.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 98.0 49.9 0.1 0.2 31.4 0.2 0.1 0.0 0.0 0.8 18.9 0.0 258.3 21.0 99.2 0.0 25.0 0.6 6.5 0.0 0.0 21.6 5.0 0.1 0.0 77.3 0.4 5.1 1.6 0.0 5.9 2.2 2.4 3.0 2.6 2.5 2.3 4.2 3.2 4.3 3.8 3.2 4.5 0.3 0.0 1.3 0.0 1.4 1.7 19.3 72.4 0.0 0.0 0.1 0.4 24.4 0.0 229.3 0.0 0.0 2.5 0.0 261.2 0.0 4.6 153.2 0.5 0.0 0.6 1.8 0.8 0.2 25.3 1.3 1.5 7.7 0.1 91.0 0.0 0.0 0.6 25.0 0.0 0.2 51.6 36.7 10.2 38.8 45.5 1.2 16.6 0.0 19.7 3.5 3.9 0.0 0.0 0.2 68.6 299.9 0.4 6.4 6.5 1.5 0.1 155.9 0.1 6.6 0.2 10.9 1.1 0.6 0.3 1.4 267.5 3.8 0.0 8.2 249.2 DISC1 ENSG00000162946 "DISC1 scaffold protein" Q9NRI5 1 231626790-232041272 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 21.7" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 113.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "THP-1: 11.4;TIME: 8.7;WM-115: 8.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA048911 Supported "Intermediate filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 43: THP-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Intermediate filaments, Cytosol" "HPA048911: AB_2732549" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (2.57e-2)" "unprognostic (3.36e-2)" "unprognostic (6.69e-3)" "unprognostic (1.41e-1)" "unprognostic (9.49e-2)" "unprognostic (1.71e-1)" "unprognostic (8.89e-2)" "unprognostic (9.53e-2)" "unprognostic (1.31e-4)" "unprognostic (1.74e-2)" "unprognostic (2.02e-1)" "unprognostic (5.94e-2)" "unprognostic (1.94e-1)" 2.4 1.4 5.3 3.1 5.4 2.6 1.9 3.9 5.6 2.1 2.6 1.5 1.1 1.5 0.5 1.3 1.1 2.6 9.0 4.2 4.9 1.1 1.4 1.7 2.4 6.9 5.8 4.4 0.8 1.1 1.0 7.3 6.9 1.2 1.2 21.7 2.0 0.9 1.4 1.2 1.3 1.4 5.6 2.9 1.0 0.9 7.3 3.1 1.8 1.1 1.7 1.6 1.3 7.7 0.0 0.4 4.0 0.1 0.1 0.3 2.8 1.6 3.6 4.1 3.5 1.4 0.8 0.1 4.8 1.3 1.0 0.0 0.3 0.1 3.7 2.6 1.7 2.2 0.3 4.0 0.5 3.7 5.1 2.2 0.7 1.4 1.2 2.8 3.8 2.7 0.0 1.4 4.6 0.4 1.1 5.6 2.0 0.0 1.5 2.7 1.1 0.4 0.1 0.0 0.7 2.2 1.4 0.0 2.4 1.0 0.0 11.4 8.7 2.1 2.3 1.0 0.9 0.9 0.7 0.0 1.7 5.6 8.8 0.1 0.8 0.0 0.2 0.8 0.1 0.0 0.4 0.0 1.0 0.1 0.4 0.1 0.7 0.2 0.4 0.6 0.1 0.2 5.3 5.4 3.9 5.6 4.2 4.9 6.9 5.8 6.9 5.6 7.3 7.7 6.7 0.0 1.1 0.0 2.1 0.9 0.5 0.7 3.4 23.3 2.0 1.8 7.2 0.0 1.2 3.7 8.4 8.0 2.0 0.5 0.0 0.6 16.6 3.4 2.1 6.7 0.0 2.1 0.0 1.1 0.8 3.0 0.0 4.5 7.0 8.0 10.0 0.0 11.3 0.0 0.0 0.1 0.0 13.0 12.6 23.2 0.9 13.7 3.6 0.0 5.6 2.4 2.1 0.0 0.0 2.0 0.3 1.5 2.1 0.7 0.0 0.2 2.5 113.1 0.0 4.6 2.7 1.4 1.6 0.5 1.1 2.5 5.8 8.1 0.7 0.6 DLL1 ENSG00000198719 "Delta like canonical Notch ligand 1" O00548 6 170282206-170306565 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 53.9" "Cell type enhanced" "Detected in many" "Adipocytes: 88.8;Basal keratinocytes: 66.9;Basal squamous epithelial cells: 82.0;Enteroendocrine cells: 51.9;Intestinal goblet cells: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 3.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 3.3" "Cell line enhanced" "Detected in some" "HaCaT: 6.8;HBEC3-KT: 4.5;NB-4: 14.2;THP-1: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001255 Approved "Plasma membrane" NA NA 690000 "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "HPA001255: " "unprognostic (1.03e-1)" "unprognostic (9.22e-2)" "unprognostic (2.17e-3)" "unprognostic (1.95e-1)" "unprognostic (2.89e-2)" "unprognostic (6.35e-2)" "unprognostic (1.63e-2)" "unprognostic (1.89e-1)" "unprognostic (9.22e-2)" "unprognostic (1.14e-2)" "unprognostic (1.39e-2)" "unprognostic (2.64e-2)" "unprognostic (5.23e-3)" "unprognostic (3.50e-1)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.66e-1)" 20.9 8.6 2.8 2.1 6.9 0.7 19.2 3.3 4.5 21.1 0.2 15.4 3.9 10.1 0.3 21.9 11.5 0.8 15.9 2.2 2.9 12.5 6.4 13.1 1.9 6.0 5.1 4.2 16.9 0.3 6.2 1.2 4.8 28.7 0.9 0.4 17.7 1.1 5.3 26.2 19.3 0.8 2.0 53.9 10.9 1.6 4.0 0.2 12.4 0.7 0.4 9.6 22.9 11.0 0.7 0.1 3.3 2.0 0.1 0.1 1.5 0.3 0.2 0.2 0.3 1.0 0.1 0.0 0.3 0.1 0.6 6.8 1.4 4.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.6 0.0 0.4 0.1 0.7 0.0 0.0 0.0 0.1 0.8 0.0 14.2 0.2 0.1 0.0 1.1 2.8 0.0 0.0 0.4 1.6 0.2 0.1 0.0 0.0 1.1 0.4 14.8 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.4 0.0 0.0 0.1 2.8 6.9 3.3 4.5 2.2 2.9 6.0 5.1 4.8 2.0 4.0 11.0 88.8 0.0 0.5 26.1 2.7 66.9 14.9 31.2 82.0 1.4 5.4 14.7 11.8 0.0 7.2 1.8 22.9 3.1 3.0 3.0 0.0 0.3 0.4 5.1 10.1 28.5 51.9 0.4 6.9 1.8 5.9 19.2 1.5 5.3 5.7 0.2 21.4 0.2 1.3 0.0 6.4 80.3 16.2 4.8 6.6 1.9 0.3 2.7 7.2 4.7 0.2 1.1 0.0 28.6 26.7 0.7 2.5 1.2 0.3 4.8 2.5 0.1 9.0 0.6 13.1 12.3 8.2 0.5 2.0 8.5 12.8 3.7 4.7 0.1 3.6 1.1 DMRT3 DMRTA3 ENSG00000064218 "Doublesex and mab-3 related transcription factor 3" Q9NQL9 9 976655-991732 "Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 10.2;parathyroid gland: 26.9;testis: 10.1" "Cell type enhanced" "Detected in some" "Early spermatids: 4.8;Smooth muscle cells: 2.3;Spermatocytes: 13.9;Spermatogonia: 5.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.0;HEK 293: 1.4;hTERT-RPE1: 2.1;THP-1: 2.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" HPA077685 Approved NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA077685: AB_2732357" "unprognostic (2.42e-1)" "unprognostic (2.26e-1)" "unprognostic (1.51e-2)" "unprognostic (2.13e-4)" "unprognostic (1.73e-2)" "unprognostic (3.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (3.84e-1)" "unprognostic (2.12e-3)" "unprognostic (2.91e-2)" "unprognostic (5.84e-1)" "unprognostic (1.05e-2)" "unprognostic (1.11e-1)" 3.3 0.0 0.7 0.0 0.2 0.0 1.7 0.0 1.0 0.0 10.2 0.1 0.0 0.1 0.0 0.3 0.6 0.0 0.0 1.4 0.0 0.0 0.0 0.0 2.0 0.2 0.2 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.6 0.0 0.2 0.1 0.0 0.0 10.1 0.0 0.1 5.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.7 0.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 1.0 1.4 0.0 0.2 0.2 0.0 0.1 0.0 1.4 1.5 0.0 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.3 0.5 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.8 0.0 0.0 0.4 0.0 0.0 1.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.3 13.9 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DNAJC5 "CLN4, DNAJC5A, FLJ00118, FLJ13070" ENSG00000101152 "DnaJ heat shock protein family (Hsp40) member C5" Q9H3Z4 20 63895126-63936031 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012139, HPA012737, HPA013154" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Plasma membrane" Vesicles "HPA012139: , HPA012737: AB_1847293, HPA013154: AB_1847292" "unprognostic (9.96e-3)" "unprognostic (2.75e-1)" "unprognostic (3.91e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (8.82e-6)" "unprognostic (3.04e-2)" "unprognostic (2.73e-1)" "unprognostic (2.65e-2)" "unprognostic (1.78e-3)" "unprognostic (1.51e-1)" "prognostic favorable (7.70e-6)" "unprognostic (2.24e-2)" "unprognostic (3.54e-2)" "unprognostic (4.28e-3)" "unprognostic (1.08e-2)" 12.6 22.1 30.8 10.7 33.0 16.9 11.1 10.2 39.1 11.4 2.1 17.6 11.5 12.1 5.7 42.0 11.6 7.4 25.8 36.2 31.0 17.7 12.8 18.0 9.9 27.9 23.9 8.8 22.7 21.2 28.5 8.4 30.4 16.7 6.9 28.1 16.2 11.5 14.5 19.2 17.5 8.6 13.8 22.2 20.8 10.7 26.8 8.4 16.8 9.5 8.5 13.4 16.9 25.7 25.2 23.7 19.8 18.8 19.4 15.9 14.6 28.6 27.4 49.4 23.8 52.7 30.2 9.8 31.6 28.2 22.7 36.4 15.9 53.6 16.0 8.2 11.3 19.3 17.4 25.8 18.1 19.2 43.5 18.0 39.9 22.9 11.7 19.1 24.2 16.5 19.2 8.9 22.6 17.3 21.1 30.9 7.1 21.0 26.5 21.0 10.9 10.7 16.4 22.6 21.4 13.9 30.8 48.7 17.8 11.6 23.5 75.9 43.7 42.6 14.4 20.4 21.5 11.1 5.6 13.6 42.9 25.3 25.4 0.7 3.2 2.6 3.2 3.7 1.8 1.6 1.8 2.7 2.5 1.4 2.5 2.5 3.1 1.5 3.1 3.9 3.1 2.6 30.8 33.0 10.2 39.1 36.2 31.0 27.9 23.9 30.4 13.8 26.8 25.7 12.8 6.4 17.8 19.2 10.4 20.8 18.5 25.5 20.5 60.7 17.4 14.1 31.7 14.3 23.2 23.9 62.6 18.5 19.1 71.7 13.7 20.5 48.9 23.9 8.5 18.7 32.4 10.3 37.1 37.6 18.4 12.4 27.0 23.5 1.3 12.1 23.9 27.8 43.5 79.1 38.8 33.3 14.2 51.0 24.8 123.5 7.2 31.4 14.2 25.3 36.9 27.9 22.6 19.1 26.2 59.0 41.1 12.4 17.3 39.5 62.0 22.9 29.4 47.0 13.1 9.0 13.1 13.5 13.2 28.0 22.9 30.2 15.0 13.3 28.4 64.5 DOCK8 "FLJ00026, FLJ00152, FLJ00346, ZIR8" ENSG00000107099 "Dedicator of cytokinesis 8" Q8NF50 9 214854-465259 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 45.0;lymphoid tissue: 64.8" "Cell type enhanced" "Detected in many" "Microglial cells: 506.8;monocytes: 134.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 173.6" "Group enriched" "Detected in all" 4 "dendritic cells: 53.0;granulocytes: 173.6;monocytes: 84.2" "Cell line enhanced" "Detected in many" "Daudi: 52.9;HL-60: 53.3;MOLT-4: 50.1;NB-4: 83.7;REH: 61.9;RT4: 54.3;THP-1: 158.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003218, HPA073349" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Centrosome "Nucleoplasm, Mitochondria, Cytosol" "HPA003218: AB_1078695, HPA073349: " "unprognostic (1.56e-1)" "unprognostic (5.90e-2)" "unprognostic (7.75e-2)" "unprognostic (7.55e-3)" "unprognostic (3.31e-1)" "unprognostic (6.28e-3)" "unprognostic (1.79e-1)" "unprognostic (8.12e-2)" "unprognostic (2.72e-2)" "unprognostic (6.72e-2)" "unprognostic (1.90e-1)" "unprognostic (3.89e-2)" "prognostic favorable (9.21e-6)" "unprognostic (2.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.91e-1)" "prognostic favorable (6.89e-6)" 11.0 13.3 4.3 35.7 4.4 42.2 7.3 5.2 3.9 4.3 45.0 7.3 7.3 3.0 2.9 7.2 4.3 14.6 2.0 4.0 5.9 16.5 6.1 19.7 51.1 8.8 7.6 2.0 4.2 7.7 2.6 15.3 9.1 5.1 7.3 4.5 4.6 2.8 1.0 3.0 15.4 6.2 9.3 45.6 9.5 7.5 8.8 64.8 4.9 2.5 49.6 14.8 3.3 12.8 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 1.6 1.4 52.9 3.9 0.0 0.0 2.3 0.8 0.3 0.0 18.2 2.3 0.1 0.0 0.2 0.0 53.3 7.1 0.2 9.3 0.0 0.2 0.0 0.0 0.0 11.8 25.9 0.0 3.2 50.1 83.7 0.2 0.2 0.7 61.9 0.1 21.3 0.2 54.3 0.1 0.0 0.0 0.6 3.6 1.0 1.4 158.0 10.2 0.0 0.4 0.7 0.1 10.3 0.1 0.0 0.1 33.3 0.9 65.1 56.9 73.5 12.2 52.0 10.2 25.2 15.7 13.8 53.0 23.2 11.3 11.1 173.6 24.1 84.2 13.8 15.6 22.6 4.3 4.4 5.2 3.9 4.0 5.9 8.8 7.6 9.1 9.3 8.8 12.8 5.0 9.6 33.5 2.3 112.6 6.4 2.5 1.2 45.5 3.6 12.3 10.8 2.3 18.6 4.9 7.3 77.2 70.9 101.9 1.5 1.9 1.0 33.4 1.9 0.7 9.8 8.4 35.1 1.9 6.5 4.3 5.3 12.8 3.2 24.6 12.7 2.9 2.6 58.4 0.0 4.2 12.9 2.0 115.0 49.4 14.8 3.1 107.7 8.8 506.8 134.3 1.1 74.2 4.5 2.2 1.4 24.9 0.4 94.6 1.5 1.2 12.8 8.0 4.2 13.1 30.2 20.6 22.1 13.3 9.4 3.8 42.7 111.6 1.1 1.3 3.4 DRAM2 "MGC54289, PRO180, RP5-1180E21.1, TMEM77, WWFQ154" ENSG00000156171 "DNA damage regulated autophagy modulator 2" Q6UX65 1 111117163-111140203 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018036, HPA061701" Supported Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Vesicles" "HPA018036: AB_1858134, HPA061701: AB_2684590" "unprognostic (9.38e-3)" "unprognostic (1.58e-2)" "unprognostic (2.16e-3)" "unprognostic (5.22e-2)" "unprognostic (1.12e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.57e-3)" "prognostic unfavorable (6.43e-4)" "unprognostic (2.69e-1)" "unprognostic (4.37e-3)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (1.77e-3)" 38.0 23.1 13.9 33.1 14.5 17.9 26.8 17.7 19.9 23.1 22.7 26.7 28.6 17.7 17.6 15.0 30.1 36.4 23.7 13.5 15.2 26.5 24.9 25.0 55.3 15.6 14.9 24.3 25.6 28.3 4.6 41.2 16.2 17.8 30.7 16.9 25.8 16.7 16.6 17.9 26.3 17.0 15.5 45.3 23.4 10.3 15.0 27.8 22.0 23.6 50.3 29.4 4.2 17.8 38.0 12.9 24.0 10.8 57.3 56.2 23.4 28.7 29.9 24.7 24.9 12.5 38.2 28.7 17.2 25.6 12.1 37.4 30.5 24.0 31.9 26.8 25.6 16.8 18.4 16.4 41.4 19.4 15.4 38.5 41.4 18.3 38.4 53.6 29.9 29.1 34.1 19.6 30.1 19.6 16.6 28.8 14.5 43.3 13.2 11.1 40.0 14.0 42.5 25.8 19.1 18.2 16.8 52.4 80.1 33.1 16.7 84.6 24.8 20.6 13.8 16.2 18.9 25.7 9.6 29.8 33.4 34.7 29.6 41.7 47.3 11.5 14.2 61.0 19.4 65.7 17.5 15.3 45.1 54.1 22.3 19.0 7.2 25.0 49.8 28.6 17.7 35.5 13.9 14.5 17.7 19.9 13.5 15.2 15.6 14.9 16.2 15.5 15.0 17.8 34.5 12.8 12.0 17.3 146.2 47.0 54.4 82.5 34.1 11.6 53.6 43.9 29.7 32.9 53.1 44.1 2.1 98.1 38.9 41.2 43.0 59.2 8.5 51.7 19.5 36.4 13.2 28.6 20.6 46.6 102.3 39.2 24.5 17.6 23.6 18.5 42.8 26.0 183.1 20.2 31.7 45.7 77.3 189.4 97.8 7.8 33.5 110.3 81.8 39.4 89.0 27.1 56.7 31.7 42.6 41.9 64.3 24.8 54.7 46.3 88.4 80.4 95.8 10.1 39.5 26.4 32.5 4.7 14.6 40.8 53.0 73.3 38.6 26.3 43.7 70.1 DUSP23 "DUSP25, FLJ20442" ENSG00000158716 "Dual specificity phosphatase 23" Q9BVJ7 1 159780932-159782543 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 458.5;Proximal tubular cells: 800.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HSkMC: 142.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028211, HPA045792" Approved Supported Nucleoplasm NA NA 22000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA028211: AB_2672522, HPA045792: AB_10961133" "unprognostic (1.52e-1)" "unprognostic (4.12e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-2)" "unprognostic (4.36e-2)" "unprognostic (3.22e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.16e-1)" "unprognostic (4.62e-1)" "unprognostic (3.33e-3)" "unprognostic (4.72e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (2.59e-5)" "unprognostic (8.58e-2)" "unprognostic (2.84e-2)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" 75.0 122.4 29.1 15.4 31.5 20.5 99.9 32.0 38.5 57.6 30.0 46.3 26.7 55.0 15.5 82.0 52.3 13.4 36.1 31.8 31.4 199.1 189.3 55.3 10.4 32.0 30.1 35.6 76.8 34.6 20.8 5.9 32.1 55.3 13.9 8.1 152.4 15.3 65.4 61.1 42.9 12.0 32.8 39.2 39.7 18.2 31.3 15.2 58.8 16.6 9.1 45.1 53.6 31.0 39.5 42.2 0.3 0.2 39.5 33.5 0.4 15.8 13.0 18.4 14.3 17.3 44.7 0.1 90.9 17.6 4.2 1.5 10.8 14.5 10.0 9.9 4.6 54.4 14.7 0.0 58.6 33.3 40.4 142.8 38.3 12.1 43.0 13.2 71.0 0.1 25.2 19.4 26.3 72.5 3.5 1.4 71.3 71.6 58.7 0.1 0.0 18.8 22.7 6.9 17.8 39.4 28.6 63.0 78.5 7.3 40.6 51.7 51.7 15.3 0.8 1.9 0.2 13.5 34.8 0.5 25.8 26.5 11.7 111.8 181.7 229.1 97.9 153.4 54.6 60.5 72.7 92.8 261.3 43.7 44.0 65.1 185.6 100.5 105.6 59.2 70.8 112.2 29.1 31.5 32.0 38.5 31.8 31.4 32.0 30.1 32.1 32.8 31.3 31.0 100.4 41.7 58.7 3.3 23.8 74.6 129.2 151.8 100.7 8.5 110.6 112.1 29.5 95.8 122.2 51.5 6.2 16.1 28.4 97.7 262.2 210.7 48.3 47.5 30.8 155.8 35.4 37.5 1.4 458.5 29.2 31.2 32.1 130.9 54.5 66.1 75.0 249.4 170.3 1.7 0.5 124.9 91.6 94.3 72.9 8.4 26.4 92.2 42.7 4.7 58.9 74.8 69.0 1.0 4.4 208.4 112.2 15.8 14.6 121.5 140.4 800.7 54.8 10.0 13.1 16.0 34.9 5.4 19.9 123.2 74.4 5.7 43.6 72.3 109.5 116.1 ECH1 HPXEL ENSG00000104823 "Enoyl-CoA hydratase 1" Q13011 19 38815422-38831841 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 749.9;skeletal muscle: 906.9" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 796.9;Proximal tubular cells: 880.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002907, HPA005835" Supported Supported Supported Mitochondria No No 720000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA002907: AB_1847964, HPA005835: AB_1847965" "unprognostic (1.91e-1)" "unprognostic (3.03e-2)" "unprognostic (3.64e-2)" "unprognostic (6.43e-2)" "unprognostic (5.73e-3)" "unprognostic (6.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (5.86e-2)" "unprognostic (2.24e-1)" "unprognostic (3.37e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (3.54e-1)" "unprognostic (3.52e-1)" "unprognostic (1.74e-2)" 216.0 343.0 51.2 47.6 53.7 62.3 194.2 54.1 60.3 124.9 58.6 232.9 93.5 115.3 32.3 168.4 114.0 66.8 749.9 49.3 52.5 271.6 556.1 122.1 67.8 51.8 51.8 107.2 141.4 56.0 77.1 67.1 53.4 99.5 99.9 12.8 138.6 43.3 906.9 149.0 167.4 59.7 50.6 192.3 180.5 100.7 55.0 51.0 117.9 455.1 65.7 142.4 132.4 53.3 64.0 273.8 42.0 68.8 161.0 82.0 61.8 31.7 53.2 26.6 27.1 178.8 124.8 98.6 117.2 72.8 24.1 30.1 70.9 72.9 21.1 345.3 37.7 120.7 76.5 146.1 161.3 131.9 116.9 109.0 186.6 35.1 61.2 52.3 63.4 127.3 58.4 160.8 59.6 120.0 91.8 82.2 27.8 278.8 65.9 101.8 126.2 199.0 168.7 142.6 51.4 67.2 161.0 77.1 86.5 27.3 106.4 288.4 53.7 45.5 39.3 46.5 29.6 121.0 153.2 96.4 71.4 164.9 90.7 316.1 312.9 268.0 253.6 248.2 237.2 368.4 243.5 249.1 308.6 361.3 216.5 242.4 41.6 342.7 212.8 221.5 391.8 541.8 51.2 53.7 54.1 60.3 49.3 52.5 51.8 51.8 53.4 50.6 55.0 53.3 125.4 86.6 104.7 13.1 111.1 82.2 220.0 320.8 80.8 22.4 124.0 143.8 302.7 205.9 203.2 145.3 16.7 796.9 103.4 257.7 510.6 195.4 64.5 95.7 56.9 96.4 189.2 99.9 7.1 90.1 370.6 104.1 112.7 77.0 120.9 177.6 90.7 549.4 277.6 37.0 8.6 298.9 193.3 99.0 85.2 56.7 130.8 97.5 145.9 8.4 205.1 53.0 113.3 7.1 16.0 97.0 257.5 143.0 122.1 100.1 383.0 880.0 182.6 21.4 78.9 88.4 119.7 73.3 51.3 121.6 90.8 580.9 118.6 624.2 350.0 218.1 EGLN1 "C1orf12, HIFPH2, PHD2, SM-20, ZMYND6" ENSG00000135766 "Egl-9 family hypoxia inducible factor 1" Q9GZT9 1 231363751-231422287 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 190.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 29.1" "Lineage enriched" "Detected in many" 15 "granulocytes: 29.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022129 Approved NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA022129: AB_1848046" "unprognostic (4.20e-1)" "prognostic unfavorable (2.99e-7)" "unprognostic (8.86e-2)" "unprognostic (1.26e-1)" "unprognostic (3.87e-1)" "unprognostic (1.67e-1)" "unprognostic (1.20e-1)" "unprognostic (3.87e-3)" "unprognostic (1.91e-1)" "unprognostic (3.99e-1)" "unprognostic (6.63e-2)" "unprognostic (9.71e-2)" "unprognostic (3.82e-2)" "unprognostic (1.23e-1)" "unprognostic (1.55e-1)" "unprognostic (5.65e-2)" "unprognostic (1.81e-2)" 32.8 35.6 37.5 18.1 40.8 20.0 23.9 38.8 43.2 26.3 31.6 30.0 34.0 30.8 24.5 33.6 24.2 28.2 58.7 39.9 37.2 38.8 56.5 19.1 21.1 41.6 39.0 37.5 40.0 39.0 9.3 42.6 36.8 23.8 26.1 49.9 22.0 30.3 190.7 48.6 35.5 27.6 40.9 27.6 19.1 17.1 43.4 16.7 25.5 153.4 21.3 27.0 12.0 40.9 54.2 59.9 17.5 33.7 44.8 29.4 15.8 22.7 42.2 36.3 49.4 41.3 48.0 15.5 41.7 42.4 31.7 25.1 26.8 30.1 61.0 18.6 42.5 6.7 23.5 37.7 31.5 38.5 8.1 25.4 27.5 24.9 34.2 58.6 49.3 18.5 33.9 37.9 38.3 12.2 8.9 14.4 18.4 33.4 21.0 20.0 21.7 22.7 48.0 23.4 15.9 45.3 32.9 41.4 83.1 11.2 22.4 112.8 54.3 44.3 20.8 40.5 47.2 65.7 46.4 14.7 60.4 14.0 59.4 4.2 0.5 3.1 1.2 1.0 0.7 0.7 0.9 0.8 0.8 0.7 1.0 1.8 29.1 1.6 1.8 0.7 0.5 0.4 37.5 40.8 38.8 43.2 39.9 37.2 41.6 39.0 36.8 40.9 43.4 40.9 64.7 19.2 23.2 36.6 19.8 58.5 15.0 10.7 33.0 32.3 19.4 13.3 111.9 67.2 11.6 18.4 37.5 16.2 16.6 57.6 35.2 37.8 1.2 18.5 20.2 60.6 12.7 8.2 43.9 36.2 34.2 25.9 15.3 21.2 10.1 55.6 28.9 70.6 16.9 62.2 52.6 24.6 16.2 24.1 45.3 5.0 16.1 29.8 26.6 44.0 19.0 56.9 12.3 46.3 48.3 36.6 30.9 23.0 23.9 15.1 43.2 52.3 13.5 44.0 19.7 36.4 36.6 13.1 20.9 24.9 57.5 10.4 24.9 16.0 23.5 21.3 EGLN2 "HIFPH1, PHD1" ENSG00000269858 "Egl-9 family hypoxia inducible factor 2" Q96KS0 19 40798996-40808434 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 269.1;Late spermatids: 740.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056649 Supported Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA056649: AB_2683203" "unprognostic (1.11e-2)" "prognostic favorable (2.88e-4)" "unprognostic (9.40e-3)" "unprognostic (6.01e-2)" "unprognostic (6.03e-2)" "unprognostic (6.47e-3)" "unprognostic (1.51e-2)" "unprognostic (4.74e-2)" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "prognostic favorable (4.81e-4)" "unprognostic (7.10e-2)" "unprognostic (7.48e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (9.99e-2)" "unprognostic (1.38e-3)" 57.6 58.5 99.3 50.0 99.8 52.1 47.6 95.1 140.9 70.0 79.6 65.4 34.3 53.9 31.5 40.2 45.5 39.1 67.8 103.4 96.2 54.2 57.7 74.3 62.4 97.3 99.3 59.0 36.6 27.7 44.5 48.3 97.7 59.9 28.5 16.6 39.2 45.1 40.0 27.4 46.7 40.9 90.5 116.8 47.6 232.1 99.9 41.9 55.8 40.8 44.1 57.9 57.9 98.1 46.5 123.4 55.9 54.4 71.1 51.5 36.5 49.4 41.1 68.9 75.4 102.8 45.7 41.1 41.1 59.3 62.5 29.3 70.8 56.3 36.4 51.7 40.5 54.8 76.4 39.4 76.1 42.7 71.6 63.9 58.5 65.8 37.4 43.3 86.0 44.3 79.3 37.3 73.4 32.9 78.9 70.2 48.7 72.4 42.6 72.7 27.7 27.8 74.0 70.2 51.4 46.9 80.9 62.9 67.2 47.2 83.4 114.0 80.5 85.9 61.7 35.7 59.5 18.7 29.6 75.6 63.0 61.4 65.5 93.2 72.5 190.5 85.8 83.4 91.1 85.2 101.7 90.3 62.6 90.0 105.2 89.6 261.6 61.4 82.3 45.5 100.2 110.5 99.3 99.8 95.1 140.9 103.4 96.2 97.3 99.3 97.7 90.5 99.9 98.1 2.8 22.4 16.8 0.0 43.9 48.8 55.2 33.8 17.6 40.5 3.3 0.8 22.2 31.5 30.7 3.7 14.6 58.1 19.0 83.0 0.0 15.8 269.1 0.9 1.5 49.9 44.9 30.7 0.0 10.1 26.5 27.6 23.9 1.2 17.2 0.8 72.8 33.7 66.7 21.9 0.0 33.9 48.8 39.8 62.4 740.8 63.0 26.3 40.9 0.0 38.5 24.4 60.8 0.0 0.0 14.0 71.0 52.3 8.7 67.6 54.9 1.4 23.0 17.8 39.5 14.6 17.2 159.4 52.5 14.2 38.4 132.6 33.2 2.1 43.7 69.8 ELANE "ELA2, HLE, HNE, NE" ENSG00000197561 "Elastase, neutrophil expressed" P08246 19 851014-856247 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 91 "bone marrow: 3894.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.7;Fibroblasts: 16.2;Langerhans cells: 11.1;Leydig cells: 6.2;Melanocytes: 7.2;Suprabasal keratinocytes: 7.4" "Group enriched" "Detected in some" 7 "pancreatic cancer: 3.5;stomach cancer: 3.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 4.0;neutrophil: 12.1" "Group enriched" "Detected in many" 9 "granulocytes: 12.1;monocytes: 4.0" "Cell line enriched" "Detected in some" 91 "THP-1: 3105.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015409, HPA066836, HPA073774" Enhanced "Secreted to blood" NA NA 370000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015409: AB_831596, HPA066836: AB_2685733, HPA073774: " "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-3)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.43e-2)" "unprognostic (3.92e-1)" "unprognostic (6.38e-3)" "unprognostic (5.80e-1)" "unprognostic (2.54e-2)" "unprognostic (4.06e-2)" "unprognostic (3.48e-2)" "unprognostic (1.19e-10)" "unprognostic (6.27e-3)" "unprognostic (4.00e-2)" "unprognostic (2.76e-2)" "unprognostic (4.75e-3)" 3.4 1.0 0.3 0.0 0.3 3894.9 3.4 0.1 0.7 0.5 0.2 2.0 0.4 1.0 0.0 1.1 1.4 0.1 4.0 0.3 0.2 0.7 3.3 19.4 0.6 0.1 0.2 0.5 0.5 0.0 1.2 0.8 0.1 2.9 0.0 0.0 2.4 0.1 1.5 5.4 1.8 0.1 0.1 42.6 1.4 0.4 0.2 6.3 3.1 0.0 0.0 2.1 1.0 0.2 2.0 0.1 0.0 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 3105.0 0.0 0.0 0.1 0.0 1.3 0.0 0.2 0.8 0.0 34.0 0.0 0.0 4.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 27.2 0.3 0.3 0.1 0.7 0.3 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.9 0.0 0.0 0.0 0.3 8.7 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.7 0.0 4.2 0.1 0.0 1.3 16.2 0.0 0.1 0.0 0.0 0.7 0.9 0.2 0.0 0.1 0.0 0.0 3.4 11.1 0.0 6.2 1.1 7.2 0.0 0.9 0.0 1.0 0.0 0.1 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.2 0.0 0.0 7.4 0.0 0.7 0.2 0.0 0.0 EMB MGC71745 ENSG00000170571 Embigin Q6PCB8 5 50396192-50443248 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 152.5;intestine: 72.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 108.4;dendritic cells: 133.3;NK-cells: 153.5;Proximal enterocytes: 137.5;T-cells: 150.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 281.5;U-937: 124.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.01e-3)" "unprognostic (8.65e-2)" "unprognostic (1.66e-2)" "unprognostic (1.15e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-2)" "unprognostic (8.31e-2)" "unprognostic (2.71e-1)" "unprognostic (1.17e-1)" "unprognostic (1.33e-1)" "unprognostic (1.49e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (2.76e-5)" "unprognostic (4.96e-3)" "unprognostic (1.79e-1)" "unprognostic (1.22e-2)" "unprognostic (8.86e-3)" 18.4 22.4 1.7 28.4 1.6 152.5 12.1 4.0 2.9 8.6 2.4 9.7 72.0 3.1 2.7 8.0 5.8 12.9 5.1 1.9 5.4 2.5 4.7 15.9 55.9 6.9 7.8 2.1 2.1 24.2 8.4 13.4 5.6 29.1 11.6 10.5 5.5 20.4 1.3 32.3 68.3 8.0 3.5 25.0 14.3 10.9 3.7 28.4 20.7 3.6 48.4 16.8 2.8 3.1 38.8 2.9 6.5 0.1 2.9 8.7 0.5 1.7 0.0 2.7 0.3 0.3 91.6 74.3 2.1 3.2 0.0 55.7 15.3 43.5 0.4 24.0 38.8 34.5 10.2 0.0 0.5 69.9 0.2 0.6 23.3 6.9 28.2 44.6 0.0 28.8 0.0 86.8 52.4 41.0 43.2 39.3 27.2 0.0 19.9 65.5 0.2 98.6 0.0 29.8 21.2 19.9 0.0 10.1 1.1 13.4 4.3 281.5 0.1 0.1 32.5 0.2 0.3 1.0 0.0 59.3 0.1 124.1 8.3 9.5 34.1 38.7 44.5 4.4 54.1 20.7 39.9 41.0 22.3 13.7 23.5 31.8 30.2 37.3 1.4 25.7 53.6 42.8 1.7 1.6 4.0 2.9 1.9 5.4 6.9 7.8 5.6 3.5 3.7 3.1 3.3 67.3 17.3 1.6 78.1 18.2 2.0 21.2 8.6 3.3 6.5 8.0 1.9 10.0 27.7 0.0 108.4 12.1 133.3 1.2 0.0 0.8 0.6 1.0 0.4 3.8 7.3 21.9 51.9 0.9 8.5 7.8 15.8 0.4 19.0 0.0 20.7 1.6 20.6 1.7 28.7 11.3 8.2 31.4 86.4 1.5 2.8 63.5 10.6 41.2 78.0 2.1 153.5 0.0 1.6 15.7 4.4 6.8 71.1 9.6 137.5 0.4 34.3 9.0 0.0 2.3 4.6 1.0 3.8 6.4 12.6 8.5 150.9 0.0 15.4 2.4 EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419687 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.6;parathyroid gland: 69.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 138.6;Inhibitory neurons: 172.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 12.0;HEK 293: 35.1;RH-30: 31.7;THP-1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010496 Approved "Intracellular and membrane" NA NA 660000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" 0.3 0.0 1.2 0.4 3.4 0.0 1.2 3.4 5.1 1.4 0.0 24.6 1.5 0.9 0.2 0.2 0.5 2.2 3.6 4.9 2.6 5.9 0.0 0.2 0.0 1.2 2.2 1.9 0.1 69.9 1.2 0.4 1.5 9.7 2.5 1.8 5.4 0.9 0.1 0.2 4.4 2.1 0.4 3.9 10.3 0.9 0.6 0.0 0.1 0.1 0.0 8.2 1.8 1.2 0.0 0.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 35.1 0.0 3.0 0.0 0.0 0.0 0.0 0.5 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.6 0.0 1.0 5.4 31.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 32.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.4 3.4 5.1 4.9 2.6 1.2 2.2 1.5 0.4 0.6 1.2 0.2 0.0 0.0 4.2 0.0 0.4 0.4 0.0 0.6 18.5 3.1 1.8 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 13.1 1.3 1.4 1.8 0.0 0.0 138.6 0.0 0.0 5.9 0.0 3.8 0.0 3.7 0.0 0.0 0.1 11.8 172.0 0.0 0.0 0.0 0.4 3.3 0.9 0.1 0.0 11.2 0.0 0.4 0.0 4.5 8.3 0.1 0.0 0.0 0.0 0.4 0.0 11.8 0.0 1.0 0.0 0.2 0.5 0.2 1.1 0.2 1.0 0.0 0.2 0.9 0.0 0.1 ERCC5 "ERCM2, XPGC" ENSG00000134899 "ERCC excision repair 5, endonuclease" P28715 13 102845831-102875995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.7;Gastric mucus-secreting cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA045845, HPA050374" Supported Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "HPA045845: AB_2679471, HPA050374: AB_2681106" "unprognostic (1.28e-3)" "unprognostic (1.32e-3)" "unprognostic (1.86e-2)" "unprognostic (9.28e-3)" "unprognostic (6.19e-2)" "unprognostic (8.73e-2)" "unprognostic (1.23e-1)" "unprognostic (8.72e-2)" "unprognostic (2.52e-1)" "unprognostic (2.55e-1)" "unprognostic (7.77e-3)" "unprognostic (5.76e-3)" "prognostic unfavorable (2.96e-6)" "unprognostic (3.56e-2)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "prognostic favorable (6.82e-4)" 14.1 11.1 7.8 10.9 8.6 16.3 14.5 8.9 11.8 12.2 10.5 14.5 20.1 9.2 13.4 10.7 9.7 10.8 9.8 8.1 8.2 12.6 21.8 12.8 15.2 8.5 8.2 12.5 11.3 12.3 3.7 11.3 8.5 11.7 14.3 12.6 10.5 10.8 9.5 13.2 17.1 9.6 8.0 15.2 16.3 7.0 8.4 21.3 13.5 10.8 16.5 11.2 3.9 8.4 21.5 10.5 15.4 7.4 34.4 30.5 8.9 24.5 31.1 13.6 16.7 10.8 37.9 19.3 10.4 23.4 9.4 23.8 14.3 19.6 10.1 19.4 9.7 16.6 23.7 13.3 15.9 50.9 26.3 26.1 19.2 15.7 25.6 19.6 23.1 23.4 9.5 16.5 23.9 8.0 18.7 23.5 7.7 30.2 9.9 14.9 10.9 17.9 19.3 15.7 9.0 14.1 12.6 25.0 8.8 13.6 13.9 43.4 21.4 7.5 5.5 3.7 13.1 16.1 5.0 9.4 41.3 20.7 10.9 19.2 11.9 20.4 16.2 15.0 14.6 8.9 17.1 19.8 14.3 8.8 18.4 18.2 3.5 20.5 21.1 7.4 20.7 17.7 7.8 8.6 8.9 11.8 8.1 8.2 8.5 8.2 8.5 8.0 8.4 8.4 2.2 3.2 9.5 0.0 22.2 7.1 4.7 11.5 16.5 0.0 2.0 2.0 28.6 14.3 14.0 0.0 0.0 9.6 7.3 17.6 0.0 1.6 60.7 2.4 4.8 8.6 4.9 24.8 0.0 1.2 7.5 11.0 44.9 2.1 19.0 1.7 13.2 21.2 10.5 0.0 0.0 22.3 10.2 17.2 6.5 28.3 22.1 14.0 7.2 0.0 12.6 0.0 19.6 0.0 0.0 1.7 16.7 15.8 21.5 4.0 26.6 1.5 11.4 0.0 19.7 10.6 6.7 11.6 6.3 19.1 7.0 5.7 31.3 1.7 18.2 5.0 EXO5 "C1orf176, DEM1, FLJ21144" ENSG00000164002 "Exonuclease 5" Q9H790 1 40508741-40516556 "Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 150.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028429 Supported Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA028429: AB_2092105" "unprognostic (9.44e-2)" "unprognostic (7.36e-2)" "unprognostic (3.69e-2)" "unprognostic (6.65e-2)" "unprognostic (1.66e-1)" "unprognostic (3.23e-2)" "prognostic unfavorable (9.16e-6)" "unprognostic (4.65e-2)" "unprognostic (2.24e-3)" "unprognostic (1.91e-3)" "unprognostic (4.78e-2)" "prognostic unfavorable (2.93e-4)" "unprognostic (9.95e-3)" "unprognostic (4.36e-2)" "unprognostic (4.13e-1)" "unprognostic (9.85e-3)" "unprognostic (2.53e-1)" 4.7 4.5 2.2 5.7 3.3 4.7 5.5 3.8 2.8 4.9 2.3 5.0 4.4 6.1 5.2 4.4 5.1 4.2 4.0 2.5 2.2 5.0 6.4 5.3 8.4 1.9 2.1 4.4 4.2 4.1 3.4 5.1 1.9 5.3 5.0 4.5 4.6 5.5 4.2 5.2 5.5 7.6 2.0 7.0 4.1 3.9 3.1 10.8 4.4 2.4 10.9 4.8 4.1 2.4 14.6 5.2 12.5 21.0 8.3 7.5 8.7 19.4 4.9 17.1 20.5 9.3 17.3 19.6 11.7 12.4 19.4 17.8 12.3 12.9 20.4 6.6 8.0 17.1 24.8 13.0 10.2 0.1 16.4 7.8 8.0 23.6 8.7 5.0 10.9 13.7 20.0 0.1 24.6 6.1 27.4 13.4 19.0 2.4 2.0 20.7 42.6 7.7 8.6 22.3 15.1 13.4 25.0 8.9 15.9 19.1 12.5 150.1 12.3 11.7 35.1 26.5 19.1 5.6 18.7 0.1 1.7 5.3 23.8 8.8 5.9 15.0 12.6 8.7 10.4 10.8 8.7 9.1 7.0 8.4 10.5 10.2 10.5 8.1 6.6 5.8 12.9 6.5 2.2 3.3 3.8 2.8 2.5 2.2 1.9 2.1 1.9 2.0 3.1 2.4 2.4 0.0 1.7 1.6 3.4 0.9 0.9 5.0 1.8 3.3 2.2 2.7 1.1 7.2 3.1 7.3 4.2 5.0 5.3 2.3 0.0 4.8 1.2 1.0 2.4 3.2 1.2 3.0 3.1 2.4 4.6 2.6 1.1 1.5 5.7 5.8 2.2 3.6 5.2 3.3 2.1 2.2 4.1 2.5 2.4 1.3 3.4 2.0 1.8 3.7 4.8 4.8 4.1 1.5 1.9 2.9 1.9 1.9 3.1 1.0 2.4 2.3 2.5 2.9 6.6 3.2 2.9 6.1 6.3 1.9 1.0 1.9 2.9 3.1 3.0 0.3 FAM205C FAM205CP ENSG00000187791 "Family with sequence similarity 205 member C" A6NFA0 9 34889066-34895764 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 28.9" "Group enriched" "Detected in some" 91 "Early spermatids: 275.6;Late spermatids: 489.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 103 "THP-1: 14.8" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.29e-1)" "unprognostic (1.90e-1)" "unprognostic (3.64e-2)" "unprognostic (8.64e-2)" "unprognostic (2.63e-1)" "unprognostic (1.84e-1)" "unprognostic (7.73e-2)" "unprognostic (1.85e-4)" "unprognostic (1.48e-3)" 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.1 0.1 28.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 1.9 0.0 275.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 489.3 1.2 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.6 0.0 0.5 0.0 0.0 0.0 2.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FCGR1A "CD64, CD64A" ENSG00000150337 "Fc fragment of IgG receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 93.3;lymphoid tissue: 41.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 283.3;Kupffer cells: 140.9;Late spermatids: 64.9;Macrophages: 94.9" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 131.5;intermediate monocyte: 54.7;myeloid DC: 35.6;neutrophil: 93.4" "Group enriched" "Detected in many" 53 "dendritic cells: 35.6;granulocytes: 93.4;monocytes: 131.5" "Cell line enriched" "Detected in some" 5 "THP-1: 191.6" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" 12.2 7.2 8.4 41.3 8.9 17.9 3.6 8.8 12.8 4.2 8.4 2.3 1.1 1.6 93.3 1.7 1.8 8.2 2.2 8.6 9.4 2.8 4.2 28.6 14.4 14.6 10.6 2.3 4.3 2.7 2.5 32.6 13.0 1.6 2.1 2.3 1.9 2.4 0.3 0.4 1.3 19.1 13.2 12.5 2.1 3.7 12.2 1.4 1.4 0.8 0.8 14.7 0.8 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.3 191.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 24.4 0.0 2.0 131.5 1.6 0.0 54.7 0.7 1.6 0.0 0.3 35.6 0.0 0.0 0.1 93.4 0.0 11.8 0.9 0.3 48.5 8.4 8.9 8.8 12.8 8.6 9.4 14.6 10.6 13.0 13.2 12.2 18.9 0.3 0.0 3.1 0.0 0.8 0.1 0.0 0.0 0.6 1.5 0.2 0.8 1.7 1.5 1.3 0.0 2.1 2.7 0.0 0.0 0.0 0.0 30.8 0.1 0.1 9.3 0.0 2.7 0.1 0.0 1.3 1.0 0.0 0.1 0.0 0.2 1.8 0.5 283.3 0.0 0.1 0.0 0.0 140.9 6.0 64.9 0.3 94.9 0.0 7.5 34.7 0.3 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.7 1.3 6.6 0.2 0.3 0.6 0.4 0.1 0.0 4.1 0.6 0.1 0.1 0.0 FCGR1B CD64b ENSG00000198019 "Fc fragment of IgG receptor Ib" Q92637 1 121087345-121097161 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 86.5;Kupffer cells: 51.5;Late spermatids: 14.6;Macrophages: 36.6;monocytes: 16.4;Sertoli cells: 19.7" "Cancer enriched" "Detected in single" 4 "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 31.2;neutrophil: 36.3" "Group enriched" "Detected in many" 4 "granulocytes: 36.3;monocytes: 31.2" "Group enriched" "Detected in some" 6 "NB-4: 19.8;THP-1: 73.9" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (3.21e-2)" "unprognostic (4.35e-2)" "unprognostic (1.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (9.60e-2)" "unprognostic (1.56e-2)" "unprognostic (6.42e-2)" "unprognostic (3.10e-2)" "unprognostic (8.17e-2)" "unprognostic (1.91e-1)" "unprognostic (3.65e-1)" "unprognostic (3.24e-10)" "unprognostic (8.99e-2)" "unprognostic (2.85e-2)" "unprognostic (7.86e-3)" "unprognostic (8.93e-2)" 5.0 3.0 4.4 18.9 4.5 6.6 1.8 4.5 7.8 1.0 3.7 0.7 0.5 0.7 51.5 0.7 0.8 1.9 1.1 4.6 4.7 1.4 1.7 6.8 2.2 6.1 5.7 0.6 2.6 0.7 1.0 11.0 6.2 0.8 0.8 0.8 0.9 0.6 0.4 0.2 0.7 5.8 6.0 7.2 0.9 0.7 6.2 0.4 2.1 0.1 0.3 4.0 0.4 6.4 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 5.9 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 19.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.1 0.0 0.3 1.0 73.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 31.2 0.6 0.0 19.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 36.3 0.0 12.4 0.3 0.0 8.8 4.4 4.5 4.5 7.8 4.6 4.7 6.1 5.7 6.2 6.0 6.2 6.4 0.4 0.0 2.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.1 0.6 2.2 0.0 0.6 0.0 2.1 0.8 0.1 0.1 0.0 0.0 7.7 0.2 0.2 2.0 0.0 0.8 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.4 0.4 0.3 86.5 3.3 0.1 0.0 0.0 51.5 4.1 14.6 1.2 36.6 0.0 11.2 16.4 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.4 19.7 0.6 0.1 0.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.1 FLAD1 "FAD1, PP591" ENSG00000160688 "Flavin adenine dinucleotide synthetase 1" Q8NFF5 1 154983338-154993111 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028476, HPA028486, HPA028563" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA028476: AB_10599974, HPA028486: AB_10600206, HPA028563: AB_10602286" "unprognostic (2.64e-1)" "unprognostic (2.60e-1)" "unprognostic (2.72e-1)" "unprognostic (3.84e-2)" "unprognostic (7.34e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (1.31e-1)" "unprognostic (2.32e-1)" "unprognostic (8.08e-2)" "unprognostic (6.51e-2)" "unprognostic (9.74e-2)" "prognostic unfavorable (2.55e-6)" "unprognostic (1.67e-2)" "unprognostic (5.06e-2)" "unprognostic (5.50e-2)" "unprognostic (1.17e-2)" 21.9 21.1 19.2 17.0 20.5 14.2 23.5 20.2 20.7 20.4 19.7 22.8 20.1 19.8 20.5 26.1 19.1 11.8 28.7 20.1 19.5 21.7 32.8 17.7 22.8 20.2 20.3 15.5 18.9 18.0 15.1 14.3 20.6 24.3 18.9 9.8 21.0 13.7 34.1 32.9 24.9 17.7 19.6 30.1 22.0 19.0 20.6 16.0 22.5 32.0 23.0 22.6 21.1 21.0 33.4 52.4 32.8 56.1 27.9 20.5 62.1 24.7 20.5 35.2 30.2 46.9 40.1 38.5 48.8 23.0 18.3 42.6 63.4 51.3 23.0 40.6 47.5 31.4 42.8 33.7 38.1 46.0 39.1 29.5 65.9 40.2 42.8 17.0 41.5 40.4 51.4 30.3 30.2 71.8 31.9 32.0 71.7 72.2 53.8 52.8 16.2 88.7 33.9 45.8 54.9 75.6 38.7 86.2 50.0 63.0 74.0 68.6 26.4 21.9 30.1 28.6 39.6 47.5 63.7 66.9 26.4 36.8 36.1 29.8 35.3 23.7 34.5 33.0 38.9 39.0 31.9 33.8 37.7 34.2 29.1 28.9 7.8 26.1 41.4 38.3 37.9 37.6 19.2 20.5 20.2 20.7 20.1 19.5 20.2 20.3 20.6 19.6 20.6 21.0 12.2 9.6 10.6 9.8 19.3 26.5 18.1 37.1 23.3 15.7 16.4 15.9 39.4 20.0 22.6 25.8 6.2 42.5 16.9 22.1 31.3 24.4 25.3 15.4 12.0 14.1 12.0 19.0 8.2 28.2 42.6 12.1 25.0 12.6 8.8 21.2 11.7 27.0 27.6 15.2 6.3 20.8 28.5 18.1 11.1 77.6 10.2 14.8 14.2 5.6 34.7 23.3 32.0 4.5 8.2 25.4 14.9 9.8 18.3 26.1 30.3 32.9 19.3 17.2 6.6 9.7 18.3 22.9 20.6 25.7 27.6 36.0 20.2 23.1 25.4 20.0 FOXD4 "FKHL9, FOXD4a, FREAC5" ENSG00000170122 "Forkhead box D4" Q12950 9 116231-118417 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;monocytes: 2.6" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "THP-1: 4.3" HPA012836 Uncertain Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "HPA012836: AB_2105429" "unprognostic (8.27e-2)" "unprognostic (1.09e-2)" "unprognostic (2.38e-3)" "unprognostic (4.75e-2)" "unprognostic (1.02e-1)" "unprognostic (3.87e-3)" "unprognostic (1.22e-1)" "unprognostic (4.20e-2)" "unprognostic (9.46e-2)" "unprognostic (2.52e-4)" "unprognostic (3.66e-4)" "unprognostic (7.06e-3)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" "unprognostic (2.43e-1)" "unprognostic (6.26e-2)" "unprognostic (1.02e-3)" 0.2 0.4 0.4 0.1 0.4 0.0 0.1 0.9 0.7 0.3 0.3 0.2 0.0 0.3 0.0 0.2 0.2 0.0 0.1 0.5 0.4 0.6 0.2 0.3 0.1 0.6 0.3 0.2 0.5 0.2 0.5 0.0 0.5 0.4 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.0 0.3 0.4 0.3 1.1 0.5 0.1 0.2 0.0 0.0 0.2 0.2 0.4 0.3 0.2 0.0 0.2 0.6 0.1 1.8 0.1 0.1 0.0 0.1 0.4 0.0 1.8 0.3 0.0 0.0 0.0 0.4 0.1 0.1 1.8 1.5 0.0 0.2 0.2 0.1 1.5 0.9 0.2 0.0 0.0 0.1 0.3 0.0 0.1 0.6 0.8 0.0 0.6 0.1 1.0 0.0 0.2 0.8 0.1 0.5 0.2 0.4 1.0 0.9 0.7 0.5 0.3 0.0 0.1 0.5 4.3 0.3 0.5 0.5 0.3 0.6 0.1 0.2 0.5 0.4 1.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.9 0.7 0.5 0.4 0.6 0.3 0.5 0.3 0.5 0.4 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.6 0.6 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.4 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.3 0.1 0.0 0.2 0.1 0.3 0.0 FUT4 "CD15, ELFT, FCT3A, FUC-TIV" ENSG00000196371 "Fucosyltransferase 4" P22083 11 94543840-94549898 "Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 100.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 22.8;Ductal cells: 19.3;Gastric mucus-secreting cells: 21.9;Intestinal goblet cells: 23.7;Pancreatic endocrine cells: 22.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 11.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HL-60: 37.4;NB-4: 24.2;THP-1: 46.6;U-937: 32.9" "Low region specificity" "Detected in single" "CAB000014, CAB016129" Enhanced Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "CAB000014: , CAB016129: AB_626918" "unprognostic (6.36e-2)" "unprognostic (7.53e-2)" "unprognostic (4.70e-3)" "unprognostic (2.46e-3)" "unprognostic (1.46e-2)" "unprognostic (2.29e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (3.64e-4)" "unprognostic (7.26e-2)" "unprognostic (4.14e-1)" "unprognostic (4.81e-3)" "unprognostic (1.27e-1)" "unprognostic (9.08e-3)" "unprognostic (8.17e-2)" "unprognostic (1.37e-1)" "unprognostic (4.04e-1)" "unprognostic (3.10e-3)" 3.7 1.2 1.3 4.7 1.1 100.8 2.5 1.2 1.4 2.3 0.2 9.2 12.3 2.8 1.2 1.8 2.1 3.7 1.7 1.6 1.1 1.9 1.5 2.1 3.7 1.3 1.0 2.9 6.7 0.5 1.3 3.1 1.3 1.6 8.7 1.6 6.8 2.2 0.9 0.8 10.8 2.5 1.6 3.6 10.8 1.3 1.4 3.7 1.2 1.1 2.8 2.1 1.3 1.9 2.9 1.4 1.7 0.0 5.3 4.8 8.9 2.6 1.3 2.3 2.5 12.5 4.0 0.0 6.1 4.4 1.2 1.4 2.9 0.3 2.1 19.1 2.9 9.4 2.2 0.3 2.7 37.4 8.0 4.1 0.1 2.9 0.0 0.5 3.6 8.3 9.7 0.0 2.7 1.4 7.9 24.2 3.4 11.6 3.4 6.9 0.0 0.0 2.4 1.9 2.4 0.9 1.5 3.7 1.5 5.1 2.1 46.6 3.3 1.8 4.9 0.0 1.0 1.1 0.6 0.0 1.6 32.9 1.1 0.5 0.8 0.7 0.2 0.4 0.1 0.1 0.2 0.3 0.4 0.1 0.2 0.1 0.3 0.2 1.2 0.5 0.5 0.2 1.3 1.1 1.2 1.4 1.6 1.1 1.3 1.0 1.3 1.6 1.4 1.9 2.9 0.0 0.0 1.3 1.8 1.7 3.0 0.9 1.2 1.0 1.8 1.8 0.9 22.8 1.9 1.8 4.2 15.6 2.6 12.1 0.0 19.3 0.3 1.1 2.8 2.3 10.2 3.4 1.5 17.9 3.2 6.0 21.9 3.3 0.0 2.6 3.9 1.0 9.0 0.0 1.9 23.7 0.0 12.9 3.5 0.8 4.4 5.2 3.6 3.7 13.6 0.4 0.0 3.0 3.4 22.5 5.8 1.2 0.5 2.9 11.6 2.4 1.7 7.9 0.0 3.1 2.6 1.7 3.5 2.1 0.6 2.2 3.1 2.0 17.9 1.4 FUT7 ENSG00000180549 "Fucosyltransferase 7" Q11130 9 137030174-137032088 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 3.9;brain: 2.5;lymphoid tissue: 6.1" "Group enriched" "Detected in some" 8 "dendritic cells: 66.9;Langerhans cells: 38.7;monocytes: 20.7;NK-cells: 28.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 210.0" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "NB-4: 23.7;THP-1: 24.0;U-937: 14.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA042780 Approved "Golgi apparatus" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus" "HPA042780: AB_2678162" "unprognostic (1.33e-2)" "unprognostic (4.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (5.42e-2)" "unprognostic (5.01e-6)" "unprognostic (2.50e-1)" "unprognostic (2.35e-2)" "unprognostic (6.75e-4)" "unprognostic (4.68e-1)" "unprognostic (1.72e-2)" "unprognostic (3.20e-1)" "unprognostic (6.69e-6)" "unprognostic (3.99e-2)" "unprognostic (4.14e-2)" "unprognostic (1.03e-1)" "unprognostic (8.75e-2)" 0.3 0.1 0.6 1.7 1.7 3.9 0.1 1.0 1.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.1 0.7 1.2 0.1 0.1 0.9 4.6 1.9 1.2 0.0 0.0 0.0 0.2 0.1 1.1 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.4 0.1 0.7 6.1 0.3 0.2 1.2 1.0 0.2 0.4 3.2 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 23.7 0.0 0.2 0.0 1.2 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 2.0 7.5 1.5 10.4 1.6 52.5 20.1 52.1 28.9 21.7 5.5 0.9 4.3 91.6 127.1 0.2 210.0 90.2 15.4 0.6 1.7 1.0 1.3 0.7 1.2 1.9 1.2 1.1 0.7 1.2 2.5 0.1 0.0 0.0 0.0 3.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 66.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.2 0.0 3.7 38.7 0.0 0.0 2.7 0.0 0.0 20.7 0.0 28.8 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 4.6 0.0 0.7 0.0 GALR2 GALNR2 ENSG00000182687 "Galanin receptor 2" O43603 17 76074781-76077537 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 7.7" "Cell type enhanced" "Detected in some" "B-cells: 1.7;Endometrial ciliated cells: 1.0;Macrophages: 1.5;Respiratory ciliated cells: 1.6;Spermatogonia: 1.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.4;NTERA-2: 2.0;PC-3: 1.3;THP-1: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA044513 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA044513: AB_10962510" "unprognostic (1.26e-2)" "unprognostic (1.04e-2)" "unprognostic (1.16e-1)" "unprognostic (1.37e-2)" "unprognostic (2.62e-2)" "unprognostic (3.54e-1)" "unprognostic (3.49e-2)" "unprognostic (3.43e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-1)" "unprognostic (9.32e-5)" "unprognostic (2.31e-1)" "unprognostic (2.11e-3)" "unprognostic (1.24e-1)" "unprognostic (2.39e-1)" "unprognostic (4.04e-2)" "unprognostic (8.14e-2)" 0.1 0.1 0.2 0.3 0.0 0.9 0.0 0.1 0.2 0.3 0.0 7.7 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.4 0.1 0.2 0.1 0.0 0.4 0.2 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.3 5.8 1.7 0.3 0.2 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.9 0.2 0.2 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.1 1.1 0.0 0.7 1.2 0.1 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.1 0.1 2.0 0.0 1.3 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.7 0.3 0.2 0.0 0.3 3.0 0.1 0.1 0.3 0.1 0.2 0.3 0.1 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.2 0.2 0.4 0.4 0.2 0.4 0.3 0.4 0.0 0.1 0.0 0.0 0.0 1.7 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.9 0.0 0.4 0.0 0.0 0.1 0.2 0.3 0.0 0.2 0.4 1.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.2 0.1 0.0 0.3 0.4 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.4 0.2 1.6 0.0 0.0 0.0 0.1 0.7 1.1 0.0 0.1 0.3 0.3 0.0 0.2 0.4 GGPS1 GGPPS1 ENSG00000152904 "Geranylgeranyl diphosphate synthase 1" O95749 1 235327350-235344532 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isoprene biosynthesis" Transferase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 212.7;Late spermatids: 290.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029472, HPA050727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "HPA029472: AB_10696206, HPA050727: " "unprognostic (7.45e-2)" "unprognostic (3.18e-2)" "unprognostic (1.25e-1)" "unprognostic (2.23e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-3)" "prognostic unfavorable (6.69e-4)" "unprognostic (4.50e-2)" "unprognostic (3.66e-2)" "unprognostic (3.77e-3)" "unprognostic (2.66e-2)" "unprognostic (8.77e-3)" "unprognostic (1.95e-2)" "unprognostic (1.99e-1)" "unprognostic (3.35e-2)" "unprognostic (1.41e-1)" "unprognostic (1.70e-2)" 24.0 23.5 20.4 17.3 21.4 7.8 34.1 23.0 27.6 24.5 18.5 24.8 21.2 23.3 30.4 22.4 21.2 20.0 23.5 21.1 22.5 27.8 21.7 20.1 21.3 21.8 20.6 23.3 16.4 21.1 17.6 19.2 22.3 29.4 23.9 38.8 31.2 19.7 29.8 20.3 20.6 25.7 22.3 20.5 20.4 48.2 20.9 27.6 27.4 28.9 21.9 23.6 17.0 25.7 41.3 22.3 54.5 41.5 41.7 59.9 20.5 36.2 50.7 23.6 33.1 17.5 64.5 28.1 51.3 40.6 38.1 33.5 29.4 37.8 31.2 28.8 54.4 24.0 19.7 29.9 46.9 30.0 19.7 39.3 66.5 32.2 43.0 41.8 42.5 46.2 58.5 24.7 31.5 24.6 37.0 35.7 46.4 109.9 11.5 22.6 17.3 32.6 66.2 22.4 43.3 59.8 27.3 61.5 54.7 20.1 76.7 46.5 35.9 27.9 20.8 47.6 34.7 42.0 55.8 34.3 35.4 33.3 51.4 43.7 31.0 48.5 31.5 37.3 32.1 38.6 39.5 33.8 30.4 32.8 36.2 33.4 27.8 31.9 54.2 25.2 42.5 36.8 20.4 21.4 23.0 27.6 21.1 22.5 21.8 20.6 22.3 22.3 20.9 25.7 18.3 32.1 34.5 16.3 27.2 39.9 60.4 64.6 27.9 32.1 29.1 22.4 24.5 17.2 39.5 20.2 43.8 30.7 24.1 21.4 72.4 37.5 212.7 16.8 15.1 29.4 17.4 12.0 26.5 28.3 43.7 31.0 14.3 12.9 24.6 16.4 28.9 13.0 26.8 48.8 25.7 26.1 69.2 26.9 49.0 290.7 35.8 24.3 67.6 20.6 36.7 55.4 36.0 15.6 23.2 31.8 23.3 35.0 8.5 65.6 29.3 61.3 30.4 51.2 26.3 26.1 32.5 111.6 50.0 18.7 40.6 47.1 33.0 30.9 22.7 55.9 GMFG ENSG00000130755 "Glia maturation factor gamma" O60234 19 39328353-39342372 "Plasma proteins, Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 577.4;lymphoid tissue: 460.7" "Cell type enhanced" "Detected in many" "Adipocytes: 304.3;Hofbauer cells: 467.5;Kupffer cells: 523.4;Langerhans cells: 343.2;Macrophages: 409.6;monocytes: 409.4;NK-cells: 423.3;T-cells: 370.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 356.7;HMC-1: 602.6;JURKAT: 464.5;Karpas-707: 494.4;NB-4: 361.6;REH: 409.8;THP-1: 641.5;U-937: 482.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002954 Uncertain Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA002954: AB_1078997" "unprognostic (1.22e-2)" "prognostic favorable (7.35e-4)" "unprognostic (2.37e-2)" "unprognostic (1.21e-3)" "unprognostic (9.93e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-1)" "unprognostic (4.84e-2)" "unprognostic (1.00e-1)" "unprognostic (2.09e-1)" "unprognostic (3.09e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.11e-6)" "unprognostic (3.01e-1)" "unprognostic (8.76e-3)" "unprognostic (1.06e-1)" "unprognostic (5.27e-3)" 111.6 26.3 27.1 188.6 27.4 577.4 71.3 26.9 41.6 26.0 29.3 45.6 33.8 20.7 19.6 19.7 29.0 60.8 25.1 27.9 29.1 36.8 65.9 117.7 299.5 30.7 30.1 9.2 14.4 15.6 10.8 102.4 30.5 18.5 53.2 2.0 18.9 15.0 11.4 16.2 75.0 47.8 29.1 325.3 41.5 7.4 28.6 460.7 37.6 23.6 262.7 93.5 18.3 32.6 1.4 0.0 2.0 0.4 0.0 0.0 0.7 1.1 0.3 0.3 0.2 0.3 33.1 309.6 2.4 0.3 0.1 1.5 0.0 0.7 1.2 99.7 0.5 329.7 0.4 3.5 5.1 356.7 602.6 0.7 0.6 0.5 0.8 0.8 19.2 464.5 12.3 494.4 2.4 0.0 316.6 361.6 0.6 0.1 0.2 409.8 3.2 196.8 0.5 40.9 0.8 0.5 1.3 1.9 2.1 0.6 0.8 641.5 175.7 0.2 3.2 0.8 1.1 26.9 107.3 340.0 1.7 482.4 2.7 4389.0 1574.5 3622.3 720.9 1447.6 773.8 812.5 1058.2 894.4 1139.9 742.7 1044.5 858.2 5262.9 908.0 1686.2 459.6 1840.4 2617.7 27.1 27.4 26.9 41.6 27.9 29.1 30.7 30.1 30.5 29.1 28.6 32.6 304.3 28.9 97.6 0.0 211.7 18.6 4.4 0.3 2.8 0.0 4.2 9.4 3.2 11.5 17.3 0.0 0.0 3.6 273.5 0.9 0.0 1.1 11.8 0.6 2.2 176.4 0.0 119.4 0.5 0.7 4.0 18.2 9.7 0.8 238.0 0.3 272.4 11.8 467.5 0.0 0.4 0.3 2.0 523.4 343.2 30.4 1.8 409.6 74.7 1.9 409.4 0.7 423.3 0.5 0.3 0.3 0.0 0.4 216.8 1.1 0.3 4.6 8.9 0.3 46.0 4.2 26.4 8.6 3.3 1.4 14.8 5.5 370.6 2.3 1.1 4.1 GPR18 ENSG00000125245 "G protein-coupled receptor 18" Q14330 13 99254732-99261744 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.7;lymphoid tissue: 38.9;testis: 13.0" "Group enriched" "Detected in some" 4 "Early spermatids: 172.6;Late spermatids: 190.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 65.3;NK-cells: 52.9;T-cells: 41.9" "Group enriched" "Detected in some" 4 "Daudi: 8.1;THP-1: 20.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013873 Enhanced NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "HPA013873: AB_1849285" "unprognostic (3.87e-6)" "unprognostic (1.31e-3)" "unprognostic (3.22e-2)" "unprognostic (1.31e-6)" "unprognostic (2.89e-1)" "unprognostic (7.55e-4)" "unprognostic (4.27e-5)" "unprognostic (3.45e-3)" "unprognostic (2.31e-3)" "unprognostic (5.43e-2)" "unprognostic (9.70e-2)" "unprognostic (4.03e-1)" "unprognostic (3.20e-6)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (6.92e-3)" 0.4 0.1 0.2 12.2 0.3 9.7 0.2 0.7 0.4 0.3 0.9 0.9 1.0 0.4 0.2 0.5 0.2 1.2 0.3 0.2 0.1 0.3 0.9 0.7 38.9 0.7 0.2 0.1 0.1 0.0 0.1 0.1 0.4 0.4 1.0 0.0 0.9 0.1 0.1 0.3 4.1 0.2 0.1 10.5 1.5 13.0 0.3 7.9 0.4 0.1 32.5 2.1 0.4 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 2.9 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 20.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 3.5 0.0 0.2 1.9 0.5 24.4 5.5 41.3 65.3 22.1 34.0 12.6 53.3 41.9 38.9 2.2 52.9 5.3 12.5 6.4 13.1 0.2 0.3 0.7 0.4 0.2 0.1 0.7 0.2 0.4 0.1 0.3 0.4 0.2 0.0 1.3 0.3 44.7 0.3 0.0 0.0 0.0 1.0 0.1 0.3 1.0 0.0 0.6 0.0 0.0 0.0 14.4 0.1 0.0 0.0 172.6 1.3 0.2 0.2 1.2 6.1 0.4 0.0 0.0 0.2 1.1 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.3 1.2 190.5 0.9 3.9 0.0 0.0 0.6 0.0 18.6 0.5 0.1 0.0 0.1 1.2 1.4 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.2 1.8 0.4 0.0 0.3 0.0 20.5 0.1 0.1 0.1 GSC2 GSCL ENSG00000063515 "Goosecoid homeobox 2" O15499 22 19146993-19150292 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "brain: 1.2;retina: 1.1;testis: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "pons: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "THP-1: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA043011 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 43: THP-1 - Innate immune response" "HPA043011: AB_10959883" "unprognostic (3.29e-1)" "unprognostic (1.56e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GUCY2F "CYGF, GC-F, GUC2DL, RetGC-2, ROS-GC2" ENSG00000101890 "Guanylate cyclase 2F, retinal" P51841 X 109372906-109482086 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "cGMP biosynthesis, Sensory transduction, Vision" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 145 "retina: 42.2" "Cell type enriched" "Detected in some" 26 "Rod photoreceptor cells: 31.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "THP-1: 1.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 43: THP-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.91e-1)" "unprognostic (4.45e-2)" "unprognostic (2.96e-1)" "unprognostic (2.23e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.4 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 HAL HIS ENSG00000084110 "Histidine ammonia-lyase" P42357 12 95972662-95996365 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 198.2;skin 1: 61.1" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 129.6" "Cancer enriched" "Detected in some" 11 "liver cancer: 23.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basophil: 56.9;neutrophil: 73.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 73.3" "Cell line enhanced" "Detected in some" "BEWO: 2.2;NB-4: 2.8;THP-1: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038547, HPA038548" Enhanced Approved Cytosol NA NA 280000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA038547: AB_10669541, HPA038548: AB_10673175" "unprognostic (3.39e-1)" "unprognostic (4.46e-2)" "unprognostic (1.53e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (5.05e-2)" "unprognostic (2.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-3)" "unprognostic (1.89e-2)" "unprognostic (3.74e-1)" "unprognostic (4.03e-2)" "unprognostic (2.87e-2)" 1.4 0.3 0.1 2.9 0.1 11.5 2.2 0.1 0.4 0.8 0.1 0.5 0.6 0.4 0.0 1.0 0.7 0.6 0.3 0.1 0.1 0.3 198.2 2.3 0.5 0.1 0.1 0.2 0.9 0.1 3.0 0.4 0.1 0.2 0.4 0.0 0.6 0.1 0.2 61.1 0.8 0.5 0.0 7.6 0.4 0.1 0.1 0.5 0.2 0.6 1.4 0.5 1.4 0.2 0.4 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.4 0.4 0.0 0.6 0.3 0.2 0.1 0.2 0.3 0.0 0.1 0.1 0.0 0.1 2.8 0.9 0.1 0.4 0.2 0.1 0.0 0.1 0.6 0.1 0.3 0.3 0.0 0.0 0.0 0.0 11.4 0.1 0.1 0.1 0.1 0.1 0.4 0.5 0.1 0.0 1.7 0.0 56.9 15.1 2.4 0.0 5.7 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 73.3 0.7 13.6 0.3 0.2 4.4 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.0 1.1 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.7 2.8 0.3 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.1 3.2 2.0 0.4 0.0 9.7 0.2 0.2 0.7 0.1 0.5 15.0 0.0 0.1 2.5 129.6 0.3 0.0 0.1 0.1 0.0 7.7 0.8 0.0 0.0 3.5 0.0 0.0 6.3 0.0 1.0 0.0 0.0 0.0 1.3 0.0 0.4 0.2 1.2 0.7 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 2.8 0.0 0.6 0.0 0.3 0.1 HAX1 "HAX-1, HCLSBP1, HS1BP1" ENSG00000143575 "HCLS1 associated protein X-1" O00165 1 154272589-154275875 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055141, HPA075289" Approved Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA055141: AB_2682714, HPA075289: AB_2686742" "unprognostic (1.32e-1)" "unprognostic (2.68e-1)" "unprognostic (9.50e-2)" "unprognostic (6.93e-2)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (1.55e-3)" "unprognostic (2.34e-1)" "unprognostic (2.20e-1)" "unprognostic (9.09e-3)" "unprognostic (3.09e-2)" "unprognostic (8.91e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (1.52e-1)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (3.96e-1)" 58.6 63.0 100.0 43.6 105.5 36.8 74.4 105.2 124.1 60.0 100.6 62.0 48.0 46.2 100.1 53.7 61.7 40.4 168.6 100.5 107.9 76.1 104.0 45.2 58.3 102.1 99.9 72.9 85.5 84.9 88.6 40.5 102.9 55.5 63.3 54.1 85.8 63.8 256.7 48.8 43.2 64.1 105.1 47.1 66.3 69.5 105.0 67.4 69.2 242.7 77.3 58.5 48.9 103.3 115.3 100.7 84.2 178.0 100.3 111.8 132.1 109.8 178.7 227.0 207.5 126.6 125.7 170.9 150.7 188.0 105.9 100.0 190.7 151.3 172.3 171.0 140.8 81.8 76.5 104.4 221.5 172.5 167.0 104.4 274.2 172.8 206.3 82.2 129.7 246.1 166.1 244.8 145.6 260.9 169.9 136.1 88.7 277.4 213.2 121.3 59.7 326.7 115.4 60.8 123.2 121.7 96.4 228.2 326.7 137.5 190.0 454.8 64.5 92.7 122.7 97.7 148.8 284.8 315.9 315.3 139.0 158.4 153.4 266.5 97.6 215.4 113.7 121.9 129.3 136.1 139.2 128.3 118.6 142.2 166.5 132.6 61.1 116.7 150.1 122.8 183.3 163.9 100.0 105.5 105.2 124.1 100.5 107.9 102.1 99.9 102.9 105.1 105.0 103.3 69.9 28.9 37.6 7.2 125.2 74.6 112.2 118.8 60.9 57.0 92.8 123.1 106.9 62.9 71.6 46.0 47.9 84.8 76.1 54.1 181.9 93.3 147.6 41.3 36.6 65.6 57.6 66.0 12.0 106.4 132.1 62.2 36.7 34.0 99.6 80.6 61.4 90.3 98.7 40.4 12.9 67.1 91.6 63.9 79.3 104.6 61.2 66.8 87.2 9.4 128.5 91.1 91.6 7.5 17.1 84.6 63.6 62.1 192.9 92.5 128.7 141.8 59.3 97.5 59.2 58.2 76.0 223.8 112.0 71.0 76.4 88.8 97.7 74.3 71.7 101.7 HDGF HMG1L2 ENSG00000143321 "Heparin binding growth factor" P51858 1 156742109-156766925 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "DNA-binding, Growth factor, Heparin-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026035, HPA048728, HPA053422" Enhanced Enhanced Nucleoplasm "Secreted to blood" NA NA 790000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 43: THP-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB026035: , HPA048728: AB_2680503, HPA053422: AB_2682146" "unprognostic (2.80e-1)" "unprognostic (9.63e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (9.06e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (2.43e-8)" "unprognostic (9.80e-3)" "unprognostic (2.34e-2)" "prognostic favorable (9.84e-4)" "unprognostic (2.45e-3)" "unprognostic (3.67e-2)" "unprognostic (1.40e-3)" "unprognostic (8.66e-3)" "unprognostic (2.14e-1)" "unprognostic (2.06e-1)" "unprognostic (3.86e-2)" 96.3 89.7 95.9 72.8 98.8 305.3 90.6 98.4 113.4 91.4 98.0 109.2 130.2 77.6 70.0 186.3 112.8 62.5 119.0 92.8 95.1 135.4 222.3 113.5 64.6 106.3 99.7 86.8 93.2 92.8 67.8 71.8 98.8 81.7 118.1 68.9 96.6 56.8 234.9 155.3 128.4 70.5 100.8 77.2 99.1 42.6 99.6 157.2 90.7 132.5 114.9 106.7 102.7 105.7 491.5 249.1 258.2 125.6 150.0 203.0 296.8 158.4 406.3 366.8 234.4 279.4 500.9 335.5 310.6 325.0 158.6 338.8 408.9 365.0 356.0 276.1 299.9 278.1 339.4 241.2 202.0 411.9 227.4 152.4 335.7 292.8 560.4 278.6 272.4 249.6 387.0 260.4 293.7 369.3 345.5 459.2 472.1 755.4 347.7 384.8 156.9 435.1 401.0 162.6 396.9 432.0 380.4 480.3 199.3 319.8 387.6 621.9 242.4 181.1 286.5 230.3 408.9 364.0 486.0 555.6 238.9 318.4 235.2 6.2 9.9 9.2 6.6 8.8 4.9 5.6 5.6 5.9 11.6 6.6 5.0 4.7 5.6 5.2 10.0 11.9 8.2 6.8 95.9 98.8 98.4 113.4 92.8 95.1 106.3 99.7 98.8 100.8 99.6 105.7 51.9 70.5 99.2 12.1 35.3 147.3 185.1 90.5 76.2 66.7 89.9 66.0 91.0 98.7 75.3 71.7 27.1 44.1 72.4 121.4 80.3 112.2 48.4 144.0 79.2 66.1 124.6 217.8 12.0 132.0 107.3 66.7 62.7 91.8 30.4 67.4 35.0 164.5 52.7 53.8 12.4 104.3 48.8 45.6 89.1 47.0 40.7 71.0 39.2 14.0 57.3 71.4 25.7 5.5 16.1 165.7 59.5 45.9 59.0 281.3 138.2 118.1 126.8 34.9 19.7 70.9 57.8 27.7 28.3 108.6 159.4 54.9 50.5 83.2 114.9 228.6 HEBP2 "C6orf34, SOUL" ENSG00000051620 "Heme binding protein 2" Q9Y5Z4 6 138403531-138422197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 678.8;Urothelial cells: 1174.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 219.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016928 Approved NA NA 690000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 43: THP-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" "HPA016928: AB_1850572" "unprognostic (8.53e-2)" "unprognostic (1.54e-1)" "unprognostic (7.92e-2)" "unprognostic (6.88e-2)" "unprognostic (7.96e-2)" "unprognostic (1.48e-1)" "unprognostic (5.60e-2)" "unprognostic (1.62e-2)" "unprognostic (1.50e-1)" "unprognostic (2.48e-1)" "unprognostic (3.49e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (2.47e-5)" "unprognostic (2.76e-3)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "prognostic favorable (3.07e-4)" 168.1 34.4 13.9 15.0 11.2 31.8 147.3 13.8 13.8 50.6 14.8 51.7 21.9 35.2 28.0 131.1 30.4 12.8 78.5 11.2 15.8 42.4 72.3 26.4 7.0 14.1 17.4 27.8 37.2 14.6 27.2 13.3 14.8 52.7 19.2 10.1 72.2 10.5 132.8 80.4 32.7 13.3 13.4 17.6 54.3 7.5 22.9 8.6 27.0 33.5 12.3 51.5 81.5 12.5 42.8 8.6 13.6 45.4 42.5 17.1 88.2 45.7 12.8 6.0 9.9 23.2 28.3 1.3 74.0 24.0 29.0 40.0 13.2 22.7 3.4 31.0 60.8 17.4 8.7 42.9 24.8 27.4 0.1 20.8 25.8 6.5 22.6 32.2 23.7 31.5 40.7 23.4 10.5 34.9 9.0 83.7 17.7 22.2 33.1 29.1 20.5 26.1 26.5 31.8 31.0 5.7 47.5 85.5 29.4 21.0 27.6 219.5 28.9 14.5 40.8 18.7 46.1 36.5 31.5 17.2 25.2 41.6 9.4 5.6 7.9 5.6 1.5 8.2 2.0 5.0 4.3 2.5 7.4 2.9 2.0 1.7 14.6 1.9 5.0 4.6 6.4 2.3 13.9 11.2 13.8 13.8 11.2 15.8 14.1 17.4 14.8 13.4 22.9 12.5 106.3 19.2 31.6 5.9 48.7 117.5 387.1 73.4 71.7 28.6 274.7 262.4 160.8 190.1 98.1 121.4 14.6 273.3 49.2 231.9 295.4 304.3 4.5 167.0 104.2 91.7 102.2 38.3 1.1 578.1 408.5 70.7 72.9 229.9 45.1 38.4 74.6 547.6 93.6 18.5 1.0 169.4 79.3 84.7 58.5 10.9 67.7 70.9 58.7 8.4 98.3 90.5 51.5 3.5 1.8 678.8 224.6 66.5 68.2 510.0 115.2 353.0 72.7 38.9 59.2 78.4 89.0 11.7 58.2 201.2 204.9 291.3 59.9 29.2 141.8 1174.8 HLX "HB24, HLX1" ENSG00000136630 "H2.0 like homeobox" Q14774 1 220879431-220885059 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 86.5" "Cell type enhanced" "Detected in many" "Adipocytes: 35.7;Endothelial cells: 32.5;Hepatic stellate cells: 47.5;Hofbauer cells: 34.1;Kupffer cells: 24.8;Langerhans cells: 23.5;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 65.1;neutrophil: 55.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 65.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 32.4;THP-1: 100.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA005968 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA005968: AB_1079066" "unprognostic (6.18e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.57e-2)" "unprognostic (9.19e-3)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (5.14e-3)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" "unprognostic (3.19e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.28e-6)" "unprognostic (8.44e-3)" "unprognostic (3.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" 35.2 4.7 1.4 10.3 1.3 86.5 18.6 1.4 2.0 7.5 1.5 44.4 4.8 5.5 0.5 3.9 9.3 9.6 18.9 2.0 1.6 6.8 21.8 23.1 8.5 1.9 1.7 4.2 4.3 1.3 3.0 13.8 2.0 6.3 2.0 0.0 3.5 0.4 9.2 8.7 18.9 5.6 1.9 15.7 5.2 1.8 2.6 2.1 9.5 4.2 2.3 11.0 8.8 1.9 0.0 2.1 0.0 3.2 9.2 14.7 3.0 11.4 18.9 12.8 10.6 0.2 0.3 0.0 0.1 6.8 2.5 0.0 0.5 0.0 5.3 3.0 5.9 0.0 1.1 0.3 15.1 3.9 0.8 15.4 0.2 14.7 0.8 1.1 5.7 0.0 4.0 0.0 1.6 0.0 0.0 10.3 0.3 0.0 5.2 0.3 9.0 0.1 0.8 0.1 0.0 2.4 0.7 0.0 32.4 0.1 0.0 100.4 1.8 8.7 0.0 1.3 9.3 0.0 0.0 0.0 14.1 12.3 3.6 65.1 10.4 22.3 0.0 3.4 0.0 5.7 0.0 0.0 13.0 2.7 0.0 0.0 55.9 0.7 0.7 8.7 0.4 3.3 1.4 1.3 1.4 2.0 2.0 1.6 1.9 1.7 2.0 1.9 2.6 1.9 35.7 9.6 5.3 1.0 4.3 2.8 0.1 0.0 0.6 0.1 0.5 1.3 5.7 0.0 0.0 0.0 0.0 0.6 3.0 0.4 0.0 0.5 0.5 0.2 2.6 32.5 0.0 8.4 0.3 0.4 0.7 8.4 0.5 0.3 3.8 0.1 47.5 10.8 34.1 0.0 0.2 0.3 0.0 24.8 23.5 0.4 2.5 17.8 0.0 4.7 44.2 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.2 0.0 0.1 0.0 0.0 6.6 7.5 10.6 0.1 2.2 0.3 3.1 0.4 1.1 0.4 0.3 0.4 HOMER3 HOMER-3 ENSG00000051128 "Homer scaffold protein 3" Q9NSC5 19 18929201-18941261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 125.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 76.4;Muller glia cells: 72.6;Proximal tubular cells: 84.2;Theca cells: 322.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 15.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 353.6;THP-1: 420.0;U-266/84: 375.4" "Region enriched" "Detected in all" 6 "cerebellum: 189.2" "Low region specificity" "Detected in all" "CAB032656, HPA040999, CAB079015" Enhanced Supported Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane, Cytoplasmic bodies" "CAB032656: AB_2120801, CAB079015: , HPA040999: AB_2677242" "unprognostic (3.41e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.24e-5)" "unprognostic (1.19e-1)" "unprognostic (2.06e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.07e-1)" "unprognostic (8.88e-2)" "unprognostic (5.78e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (5.99e-2)" "unprognostic (3.76e-2)" "unprognostic (2.33e-1)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" 33.1 29.6 33.3 9.9 41.9 22.3 26.2 76.9 44.6 31.7 41.1 27.0 7.0 24.6 6.4 15.3 16.7 16.5 25.0 40.4 35.1 52.2 6.1 25.6 7.9 42.3 40.9 20.1 12.4 37.5 8.6 14.7 42.8 21.9 6.0 5.9 27.6 9.4 114.5 35.4 14.4 10.6 39.4 125.1 17.0 9.2 41.6 7.4 49.3 18.6 3.8 29.7 26.0 45.5 112.1 28.5 53.1 44.4 48.3 48.6 26.2 108.1 94.9 106.4 53.4 14.6 41.8 0.9 49.9 122.1 76.1 68.6 18.4 140.4 58.9 4.0 11.0 0.1 9.7 27.5 44.9 21.5 1.7 39.3 89.4 59.0 79.1 113.0 130.3 7.9 3.2 28.6 78.1 30.3 1.9 353.6 27.3 6.1 115.5 55.2 16.2 53.4 38.2 28.3 0.2 44.8 26.6 31.2 78.5 10.2 14.0 420.0 105.3 94.0 42.0 114.5 132.2 274.2 375.4 93.6 148.0 270.6 69.8 0.1 15.0 2.9 0.1 5.3 0.0 2.3 0.8 0.3 1.3 2.7 0.1 0.0 5.8 0.0 1.6 0.2 0.8 4.2 33.3 41.9 76.9 44.6 40.4 35.1 42.3 40.9 42.8 39.4 41.6 45.5 21.7 3.2 0.0 9.4 9.3 11.9 22.4 24.4 6.8 2.2 14.3 22.5 4.1 2.8 8.0 12.9 0.0 1.0 0.6 0.1 11.7 22.9 2.0 4.3 18.7 38.0 1.8 0.4 0.3 13.6 2.4 20.5 0.0 6.3 10.2 34.8 21.8 0.7 76.4 1.7 3.9 0.9 22.4 16.2 7.6 1.7 13.7 32.2 12.4 1.9 8.3 72.6 0.0 1.0 13.4 42.0 0.0 10.9 13.8 25.2 0.0 84.2 3.6 4.1 0.0 14.4 27.8 4.7 6.7 4.2 14.5 1.1 2.5 322.4 0.3 21.4 HRC MGC133236 ENSG00000130528 "Histidine rich calcium binding protein" P23327 19 49151198-49155396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 50 "heart muscle: 718.3;skeletal muscle: 453.0;tongue: 244.7" "Cell type enriched" "Detected in some" 17 "Cardiomyocytes: 1182.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 5.8;HSkMC: 5.6;K-562: 8.0;THP-1: 13.9;U-266/84: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA004833 Enhanced "Intracellular and membrane" NA NA 100000 "Cluster 38: Heart - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA004833: AB_1079083" "unprognostic (1.06e-1)" "unprognostic (1.04e-3)" "unprognostic (1.46e-2)" "unprognostic (4.94e-2)" "unprognostic (5.66e-2)" "unprognostic (9.75e-3)" "unprognostic (3.44e-1)" "unprognostic (1.74e-1)" "unprognostic (4.09e-1)" "unprognostic (1.62e-1)" "unprognostic (7.41e-3)" "unprognostic (5.85e-3)" "unprognostic (4.04e-2)" "unprognostic (6.68e-2)" "unprognostic (1.07e-1)" "unprognostic (1.86e-1)" "unprognostic (1.46e-1)" 9.3 3.6 2.5 0.6 2.7 0.0 5.7 3.1 4.0 6.4 2.0 2.4 0.9 6.3 5.4 4.5 9.2 2.2 718.3 2.5 2.3 3.5 1.9 2.8 0.8 2.4 2.6 4.6 1.3 1.5 1.5 2.1 2.6 4.3 0.9 0.8 8.1 2.5 453.0 2.9 2.3 2.1 2.2 0.5 1.8 1.4 2.8 0.6 4.7 244.7 0.4 3.1 3.9 2.4 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.6 5.8 0.0 0.0 1.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 13.9 0.2 0.0 0.0 0.3 0.0 0.0 4.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.7 3.1 4.0 2.5 2.3 2.4 2.6 2.6 2.2 2.8 2.4 3.7 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 1.0 0.8 1.0 1182.5 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.3 1.7 11.0 1.2 0.0 0.0 0.2 0.0 20.9 0.0 0.5 0.0 0.0 0.7 0.6 0.1 3.3 0.1 2.8 0.0 0.0 1.1 0.4 8.4 0.3 3.6 0.0 0.0 1.3 0.0 0.0 0.1 0.1 0.4 8.2 0.1 0.2 0.5 0.0 0.0 0.2 65.7 8.7 44.2 0.0 0.2 0.1 0.1 0.1 0.2 2.8 1.5 0.2 IL10RB "CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2" ENSG00000243646 "Interleukin 10 receptor subunit beta" Q08334 21 33266367-33310187 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 198.4;Extravillous trophoblasts: 164.9;Syncytiotrophoblasts: 315.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020670, HPA047550" Approved Approved Cytosol NA NA 1600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 43: THP-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "CAB020670: , HPA047550: AB_2680086" "unprognostic (8.43e-2)" "unprognostic (6.50e-2)" "unprognostic (5.88e-2)" "unprognostic (1.77e-1)" "unprognostic (1.48e-2)" "unprognostic (7.78e-2)" "unprognostic (1.97e-3)" "unprognostic (1.26e-1)" "unprognostic (5.69e-3)" "unprognostic (1.31e-1)" "unprognostic (1.19e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (5.62e-9)" "unprognostic (3.09e-1)" "unprognostic (2.76e-1)" "unprognostic (1.29e-2)" "unprognostic (1.05e-1)" 24.6 14.5 8.2 30.3 8.2 19.8 18.1 8.1 11.3 20.2 8.6 40.6 36.5 14.7 9.9 27.6 23.9 23.9 13.8 8.1 7.8 16.8 27.5 25.8 27.6 9.0 8.1 20.4 25.4 10.7 11.3 62.5 8.9 18.6 38.0 4.8 23.6 12.3 12.4 20.2 45.7 19.8 8.6 43.1 33.8 5.0 9.5 30.5 14.0 9.8 26.0 29.3 19.3 9.8 28.8 21.6 4.9 19.1 82.7 61.3 30.0 22.9 62.3 23.5 33.6 20.6 36.1 10.9 25.0 37.8 48.3 34.5 13.2 14.8 17.3 28.5 15.5 30.8 15.1 15.2 58.3 29.5 54.6 62.5 26.8 41.2 23.5 36.8 34.6 25.6 20.6 79.7 32.5 29.1 22.6 27.4 4.2 59.1 11.4 18.5 14.4 33.9 22.6 16.6 7.5 8.0 45.4 35.3 37.5 9.7 21.3 104.5 31.0 24.1 22.7 40.0 12.4 49.9 48.3 6.8 40.5 44.5 19.4 103.8 115.0 98.9 32.0 134.9 35.2 51.6 39.3 38.1 67.9 54.1 36.8 36.3 219.4 56.9 141.6 73.6 77.6 87.5 8.2 8.2 8.1 11.3 8.1 7.8 9.0 8.1 8.9 8.6 9.5 9.8 3.1 35.3 20.5 11.8 26.5 14.5 38.0 54.0 19.4 5.8 3.3 2.8 12.3 32.9 32.3 3.7 14.6 198.4 33.6 102.1 0.0 20.1 1.1 2.3 3.5 23.5 10.2 17.7 14.5 30.1 164.9 24.2 29.6 2.4 35.5 2.1 31.8 23.2 116.6 8.4 12.7 64.4 30.5 111.3 25.3 1.6 31.7 54.3 14.2 23.4 80.6 6.7 49.4 14.6 18.5 23.4 86.8 23.7 39.9 44.3 103.1 1.1 15.8 6.4 19.7 16.9 9.1 2.9 5.0 21.7 14.6 315.6 21.0 0.2 41.4 67.6 IL17RA "CD217, CDw217, hIL-17R, IL-17RA, IL17R" ENSG00000177663 "Interleukin 17 receptor A" Q96F46 22 17084954-17115694 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.9;Kupffer cells: 81.4;Macrophages: 61.4;monocytes: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HL-60: 59.9;NB-4: 52.5;THP-1: 74.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB024996 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 62000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB024996: " "unprognostic (1.92e-1)" "unprognostic (3.15e-1)" "unprognostic (1.65e-2)" "unprognostic (9.83e-2)" "unprognostic (7.66e-2)" "unprognostic (5.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-2)" "unprognostic (8.52e-2)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (1.96e-2)" "prognostic favorable (8.35e-4)" "unprognostic (2.16e-2)" "unprognostic (1.27e-1)" "unprognostic (6.51e-3)" 9.1 5.6 5.5 9.6 11.3 31.8 6.9 5.7 7.5 5.4 6.8 4.7 3.8 5.4 5.0 5.2 6.0 3.6 4.6 6.3 5.5 3.7 5.7 10.0 6.9 9.8 7.3 4.5 5.2 3.9 3.8 3.5 8.9 5.0 3.4 1.5 5.2 2.8 1.8 6.9 6.2 5.3 7.7 16.6 5.6 2.0 7.7 15.4 4.2 2.6 5.6 4.6 4.7 9.6 7.9 4.5 4.1 5.1 8.0 4.6 5.1 11.5 7.4 5.3 6.8 4.4 5.1 7.1 4.6 11.6 6.9 12.4 5.6 5.4 3.7 11.6 6.6 0.0 2.6 2.8 9.2 59.9 17.8 6.8 7.9 4.7 3.7 5.2 5.7 5.6 3.0 7.3 5.5 6.7 7.2 52.5 2.2 10.1 4.3 1.6 0.8 1.3 5.1 5.8 2.8 0.1 8.0 6.7 5.7 4.6 5.3 74.7 15.9 4.1 5.8 6.1 4.3 5.8 3.4 3.3 6.0 28.3 4.5 8.5 7.4 7.2 1.1 3.4 0.9 0.5 1.5 1.2 3.9 0.4 2.4 1.8 16.5 1.5 3.5 1.8 1.0 2.6 5.5 11.3 5.7 7.5 6.3 5.5 9.8 7.3 8.9 7.7 7.7 9.6 14.0 12.8 14.1 2.9 13.8 8.8 6.6 10.2 10.8 3.9 7.2 5.8 6.1 10.0 8.6 5.5 8.4 6.1 18.7 23.6 0.0 8.7 4.0 7.2 8.1 13.7 13.2 9.2 8.3 12.6 11.9 13.6 29.0 9.7 7.6 58.9 17.5 11.1 34.0 3.3 6.4 13.9 6.1 81.4 16.2 2.1 9.0 61.4 8.8 41.2 114.2 4.3 28.8 12.5 11.4 12.2 12.4 4.5 10.3 9.1 14.7 3.4 8.0 2.9 13.1 10.4 10.0 3.0 13.4 9.0 6.8 6.4 25.4 8.1 12.4 9.6 IRF2BP2 IRF-2BP2 ENSG00000168264 "Interferon regulatory factor 2 binding protein 2" Q7Z5L9 1 234604269-234610178 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 440.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 277.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027815, HPA062269" Approved Enhanced Nucleoplasm NA NA 13000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA027815: AB_10609994, HPA062269: AB_2684732" "unprognostic (1.15e-3)" "unprognostic (1.02e-1)" "unprognostic (3.90e-1)" "unprognostic (2.13e-1)" "unprognostic (3.41e-3)" "unprognostic (1.69e-1)" "unprognostic (1.74e-3)" "unprognostic (1.97e-2)" "unprognostic (8.77e-2)" "unprognostic (2.19e-1)" "unprognostic (3.69e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (6.42e-4)" "unprognostic (1.25e-1)" "unprognostic (2.70e-1)" "unprognostic (3.14e-1)" "unprognostic (3.77e-1)" 35.6 39.6 43.3 25.6 50.2 157.2 45.0 48.5 49.1 50.0 43.3 42.5 39.6 55.8 26.5 47.0 45.1 40.7 45.0 40.5 45.4 34.2 53.6 43.7 36.3 55.2 49.0 54.8 49.5 45.5 24.1 29.6 51.1 39.2 49.3 26.9 55.0 33.5 47.4 64.2 42.2 31.7 48.9 28.4 44.4 18.0 44.7 29.6 57.3 40.5 30.3 38.7 43.7 61.1 28.0 41.5 29.8 45.7 61.2 48.1 35.1 21.8 18.4 12.7 14.2 24.5 33.5 0.0 49.4 21.2 43.3 37.4 16.2 28.3 20.2 45.2 36.8 26.7 32.9 72.3 49.4 101.0 91.0 57.0 65.8 28.3 53.4 74.4 33.0 24.5 23.0 55.6 33.2 8.4 25.5 107.2 27.1 65.1 15.7 49.6 13.8 66.8 25.1 22.9 58.8 41.8 35.2 46.7 72.7 29.8 45.1 277.5 36.8 45.5 19.0 34.7 41.6 122.9 33.8 9.1 23.1 89.6 63.4 10.1 4.5 8.5 3.9 3.6 4.0 4.3 4.8 4.6 4.7 4.0 4.9 4.1 2.3 3.0 1.9 17.8 4.0 2.5 43.3 50.2 48.5 49.1 40.5 45.4 55.2 49.0 51.1 48.9 44.7 61.1 96.0 134.6 191.3 28.1 75.6 325.9 440.4 142.3 139.5 34.6 126.6 109.7 63.6 133.0 143.8 51.5 10.4 44.6 168.3 84.2 13.7 65.8 24.9 180.8 126.2 101.9 145.5 76.6 14.3 50.0 58.0 97.3 47.4 285.2 107.5 39.6 117.4 185.7 88.9 58.9 22.9 117.1 71.2 131.8 271.2 27.1 69.6 159.7 110.3 30.9 83.2 87.7 38.1 20.6 64.2 68.9 92.0 81.3 39.2 138.2 81.7 40.2 95.1 19.5 78.9 117.1 102.9 29.5 24.1 182.1 396.2 79.4 91.3 15.5 162.7 370.6 IRS2 ENSG00000185950 "Insulin receptor substrate 2" Q9Y4H2 13 109752695-109786583 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 51.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "hTERT-HME1: 38.1;LHCN-M2: 36.9;SH-SY5Y: 40.2;THP-1: 62.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016944, HPA054664" Approved Supported Aggresome,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Cytosol Aggresome "CAB016944: , HPA054664: AB_2682563" "unprognostic (2.87e-3)" "unprognostic (5.73e-3)" "unprognostic (4.39e-2)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (5.49e-3)" "unprognostic (2.10e-1)" "unprognostic (9.28e-2)" "unprognostic (9.70e-2)" "unprognostic (2.34e-3)" "unprognostic (1.17e-1)" "unprognostic (2.09e-2)" "unprognostic (6.21e-3)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (3.17e-2)" "unprognostic (1.24e-1)" 26.2 16.5 22.2 5.9 21.8 51.3 18.9 12.1 28.4 10.7 3.9 11.3 4.4 13.0 6.3 4.2 7.7 4.0 13.0 32.2 22.9 3.5 22.1 11.1 2.3 29.4 24.5 18.6 4.3 3.6 19.1 6.7 24.8 13.3 3.4 6.0 11.6 6.1 21.4 15.5 6.0 4.7 13.6 5.4 7.8 3.0 25.2 2.3 5.5 7.7 2.2 7.1 8.6 20.1 5.8 6.6 4.2 0.0 34.5 6.9 2.3 6.3 7.4 3.8 3.1 0.6 7.0 0.0 3.9 4.5 5.4 2.6 2.2 5.6 4.7 2.3 29.5 2.8 9.3 0.0 34.8 10.7 3.3 14.5 29.6 1.1 38.1 24.5 1.4 0.5 1.9 0.0 36.9 3.0 0.1 31.1 4.5 3.2 1.4 13.1 3.8 2.8 10.6 1.5 6.1 40.2 3.3 0.1 27.2 3.5 0.8 62.8 0.1 7.8 0.0 0.5 8.5 0.0 3.1 2.1 5.8 10.2 13.7 1.5 0.6 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 3.3 0.0 0.2 0.0 0.2 0.1 22.2 21.8 12.1 28.4 32.2 22.9 29.4 24.5 24.8 13.6 25.2 20.1 13.7 32.1 33.8 53.8 31.1 113.9 48.0 100.2 81.4 25.8 68.9 98.4 72.3 60.1 79.5 31.3 114.7 20.3 40.0 71.2 5.9 36.4 47.6 81.6 110.6 13.4 122.6 34.5 51.3 3.1 11.1 52.0 28.1 188.5 25.3 25.8 20.0 142.9 24.1 25.2 42.2 42.0 52.9 143.5 24.4 12.3 37.3 131.2 129.9 29.0 59.3 32.4 17.5 46.3 34.8 30.8 44.4 20.3 7.9 76.8 77.3 3.9 40.3 30.6 26.3 57.1 44.0 21.2 10.2 74.6 126.2 30.6 37.5 63.1 42.7 53.6 ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Group enriched" "Detected in many" 6 "dendritic cells: 417.6;Hofbauer cells: 652.4;Kupffer cells: 485.9;Langerhans cells: 259.1;Macrophages: 527.4;monocytes: 463.8;NK-cells: 959.9;T-cells: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "THP-1: 812.4;U-937: 615.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" 54.5 23.2 8.2 175.2 9.5 376.2 15.4 13.1 9.3 15.5 11.7 25.2 23.8 8.5 2.8 16.2 17.0 36.4 11.8 7.7 14.2 8.4 23.4 78.0 169.1 29.5 19.9 7.2 11.3 5.1 4.6 44.4 28.1 8.8 13.9 1.1 19.5 9.2 6.8 9.3 32.8 46.4 23.9 137.2 29.1 5.9 26.2 87.2 7.3 7.6 68.4 46.3 5.9 50.4 1.9 4.8 0.0 0.0 0.0 0.3 1.7 0.0 2.7 0.1 0.0 0.4 0.4 17.9 128.1 0.2 0.6 0.5 0.0 0.2 0.0 1.5 1.4 18.2 0.0 3.2 0.1 106.6 27.5 1.6 0.1 0.5 0.3 0.1 0.3 58.0 0.7 1.4 7.0 4.0 117.8 126.1 0.4 0.4 2.4 1.5 23.2 64.6 4.7 0.0 0.6 1.3 3.4 2.5 1.7 0.0 0.4 812.4 2.5 0.2 6.6 0.4 3.7 0.8 5.9 2.9 0.1 615.0 0.9 186.6 1848.8 1224.1 726.7 1144.9 326.6 86.1 349.7 506.5 1031.4 115.2 233.1 396.5 1386.1 585.5 1183.5 165.5 288.0 3034.2 8.2 9.5 13.1 9.3 7.7 14.2 29.5 19.9 28.1 23.9 26.2 50.4 7.1 16.0 29.6 0.3 81.7 5.5 0.5 9.6 0.6 0.0 4.1 6.5 4.0 14.3 18.6 5.5 0.0 4.0 417.6 0.3 0.0 3.4 1.0 0.6 0.5 16.8 0.0 19.6 0.5 0.4 4.8 5.3 2.6 0.7 24.1 8.2 9.7 8.6 652.4 0.0 0.3 0.2 2.0 485.9 259.1 2.8 0.6 527.4 5.4 27.2 463.8 0.4 959.9 0.0 0.2 0.6 0.1 1.5 50.5 0.6 1.8 4.2 3.6 0.8 6.6 2.1 3.2 0.2 1.0 0.9 5.1 5.6 254.5 0.0 0.3 0.7 IVD ACAD2 ENSG00000128928 "Isovaleryl-CoA dehydrogenase" P26440 15 40405485-40435947 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.0;Theca cells: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041391, HPA044250" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA041391: AB_2677449, HPA044250: AB_2678875" "unprognostic (9.30e-2)" "unprognostic (3.31e-1)" "unprognostic (1.36e-2)" "unprognostic (4.24e-2)" "unprognostic (7.53e-2)" "unprognostic (1.74e-1)" "prognostic favorable (1.95e-5)" "unprognostic (1.50e-2)" "unprognostic (2.53e-1)" "unprognostic (2.84e-2)" "unprognostic (4.08e-2)" "unprognostic (2.31e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.40e-1)" "unprognostic (3.40e-2)" "unprognostic (1.14e-1)" "unprognostic (5.46e-3)" 25.8 80.5 35.1 14.5 40.8 15.9 45.3 35.6 40.8 29.4 39.5 31.6 24.3 26.4 29.0 16.0 35.0 21.5 61.7 34.0 41.5 59.1 145.4 24.3 19.6 40.2 38.8 43.3 27.4 39.2 58.3 15.3 37.5 42.1 27.2 13.0 31.8 36.8 55.7 8.6 26.8 23.8 37.9 27.9 46.7 25.0 44.5 16.8 119.2 55.4 19.5 31.1 20.8 45.3 20.9 11.9 22.9 38.9 35.9 32.9 1.0 27.6 32.7 39.4 24.0 36.5 16.0 0.8 57.7 43.4 32.6 20.8 45.9 46.6 30.1 36.4 34.0 52.1 36.2 38.9 64.6 22.0 48.5 45.3 18.5 23.5 55.3 46.3 38.8 60.4 2.5 2.4 42.1 27.1 27.3 38.9 17.8 1.3 33.0 41.2 32.6 27.9 45.2 51.6 37.3 21.5 38.2 83.4 18.7 21.5 69.0 117.6 27.6 29.9 20.2 23.6 24.9 54.5 38.5 1.0 30.9 22.8 28.4 17.0 24.8 36.7 33.3 36.1 31.0 27.5 18.5 26.6 58.8 27.6 18.5 26.7 2.3 39.4 73.1 89.2 26.9 24.3 35.1 40.8 35.6 40.8 34.0 41.5 40.2 38.8 37.5 37.9 44.5 45.3 13.1 28.9 54.5 27.4 19.0 2.3 21.0 17.3 13.1 26.0 27.5 22.2 88.0 45.8 29.9 44.1 14.6 20.3 34.0 17.9 95.9 19.7 5.4 21.4 31.0 18.6 19.7 21.3 15.3 14.9 7.3 20.2 29.6 19.9 34.7 46.5 21.4 135.0 28.1 16.8 16.6 24.4 14.2 18.3 6.2 7.4 20.5 18.6 5.4 21.5 28.8 26.0 26.8 25.1 21.4 14.8 9.4 24.8 10.0 16.6 22.0 97.3 29.3 19.9 19.7 25.0 18.2 16.1 3.7 17.4 0.6 9.9 18.0 105.7 35.4 11.9 KCNN2 "hSK2, KCa2.2" ENSG00000080709 "Potassium calcium-activated channel subfamily N member 2" Q9H2S1 5 114055926-114496500 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 27.8;brain: 20.8;liver: 31.3" "Cell type enhanced" "Detected in some" "Astrocytes: 36.2;Excitatory neurons: 149.9;Inhibitory neurons: 97.0;Oligodendrocyte precursor cells: 63.3" "Group enriched" "Detected in some" 7 "glioma: 3.5;melanoma: 3.2;prostate cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 17.5;NTERA-2: 6.4;SK-MEL-30: 12.9;THP-1: 21.8;U-937: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038221 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA038221: AB_10673044" "unprognostic (9.22e-3)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (5.65e-2)" "unprognostic (1.43e-1)" "unprognostic (1.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (4.61e-1)" "unprognostic (3.16e-1)" "unprognostic (4.25e-1)" 0.4 27.8 7.8 0.2 10.8 0.0 0.5 11.3 14.0 2.0 2.2 1.4 0.3 2.9 0.3 0.2 0.4 0.4 6.8 20.8 7.5 3.9 31.3 2.3 0.4 11.1 4.7 0.7 4.5 0.4 7.6 0.0 6.7 9.6 0.7 2.5 0.5 4.3 9.5 1.3 0.3 2.0 9.0 0.5 0.7 3.0 8.2 0.2 0.3 6.7 0.2 2.3 1.0 11.1 0.1 0.0 0.0 0.0 0.0 0.0 2.1 17.5 2.7 0.3 0.0 0.0 0.2 0.0 0.5 0.0 2.3 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.8 0.0 0.2 0.0 0.3 0.0 1.4 6.4 0.0 0.0 0.0 0.0 0.8 0.2 0.1 2.1 0.0 0.0 0.2 12.9 0.4 0.3 21.8 0.3 0.0 0.5 1.8 0.0 0.1 0.0 0.1 2.0 7.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 10.8 11.3 14.0 20.8 7.5 11.1 4.7 6.7 9.0 8.2 11.1 1.4 0.0 1.1 36.2 0.0 0.3 0.3 0.0 0.0 7.9 0.6 1.3 15.1 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.6 0.6 0.5 0.0 8.2 0.0 0.0 149.9 0.9 0.0 0.8 0.0 1.3 0.0 0.8 5.0 18.3 0.0 0.0 97.0 1.0 0.0 1.0 0.3 0.5 0.0 0.1 21.4 6.5 0.0 0.4 0.0 63.3 9.2 1.0 0.1 0.0 1.2 4.7 0.0 0.7 0.0 7.8 0.0 0.1 0.3 0.3 6.5 0.3 0.3 0.0 0.0 0.2 0.5 0.6 KCNS1 Kv9.1 ENSG00000124134 "Potassium voltage-gated channel modifier subfamily S member 1" Q96KK3 20 45091214-45101127 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 22.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.0;Cholangiocytes: 7.2;Collecting duct cells: 1.8;Excitatory neurons: 6.2" "Cancer enriched" "Detected in many" 5 "cervical cancer: 6.1" "Region enhanced" "Detected in many" "cerebral cortex: 22.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBF TERT88: 1.3;HHSteC: 2.1;hTEC/SVTERT24-B: 1.0;THP-1: 1.8;U-87 MG: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.46e-2)" "unprognostic (2.95e-3)" "unprognostic (2.03e-1)" "unprognostic (3.11e-4)" "unprognostic (8.91e-3)" "unprognostic (6.01e-3)" "unprognostic (7.47e-2)" "unprognostic (8.94e-2)" "unprognostic (4.37e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (6.74e-2)" "unprognostic (4.65e-2)" "unprognostic (6.35e-2)" "unprognostic (5.62e-2)" "unprognostic (3.06e-2)" "unprognostic (1.15e-1)" "unprognostic (1.39e-1)" 0.0 0.4 0.9 0.1 2.9 0.1 0.2 0.0 22.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.1 4.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.5 2.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.1 0.4 0.4 0.1 0.1 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.8 0.0 0.9 0.2 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 2.9 0.0 22.8 4.1 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 2.0 0.3 0.0 0.4 0.1 0.1 0.0 0.0 0.3 0.1 1.1 7.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 6.2 0.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 KDM4A "JHDM3A, JMJD2, JMJD2A, KIAA0677, TDRD14A" ENSG00000066135 "Lysine demethylase 4A" O75164 1 43650149-43705518 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007610 Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 56: Intestine - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA007610: AB_1852006" "unprognostic (7.01e-2)" "unprognostic (1.50e-1)" "unprognostic (3.22e-2)" "unprognostic (6.18e-2)" "unprognostic (3.54e-2)" "unprognostic (5.40e-3)" "prognostic unfavorable (1.39e-5)" "unprognostic (4.88e-3)" "unprognostic (1.13e-1)" "unprognostic (5.47e-1)" "unprognostic (2.70e-1)" "unprognostic (7.95e-2)" "unprognostic (2.81e-1)" "unprognostic (2.32e-3)" "unprognostic (2.02e-1)" "unprognostic (1.92e-1)" "unprognostic (1.28e-1)" 10.6 20.6 10.7 12.2 11.3 12.1 12.8 12.7 12.4 15.1 11.8 18.0 28.0 14.2 13.0 14.4 18.0 11.8 10.0 10.7 9.3 12.7 14.8 14.7 15.6 10.7 10.4 19.7 12.7 19.1 10.9 11.2 10.9 13.7 18.5 19.6 13.3 11.4 11.1 21.8 22.6 14.9 10.0 13.9 14.4 5.7 10.7 21.6 17.3 15.7 18.0 13.7 11.8 11.2 25.1 22.6 36.6 63.6 34.5 32.6 25.3 23.4 26.4 34.7 34.6 26.0 21.7 32.5 23.5 23.4 26.3 25.3 45.1 27.6 35.4 23.2 37.8 46.5 33.7 21.2 32.7 33.4 35.9 35.4 43.2 33.7 42.3 26.6 37.0 27.9 23.5 45.1 25.5 19.6 26.4 28.2 59.9 21.5 23.0 35.0 42.2 23.9 24.3 48.8 32.1 29.1 50.5 34.2 63.3 52.8 20.0 111.5 28.1 20.6 32.8 18.7 31.9 20.7 26.7 29.2 21.3 27.8 39.3 10.2 4.9 9.0 4.4 3.7 4.9 4.3 4.3 3.6 4.1 3.1 2.9 2.6 3.0 4.1 5.2 3.6 4.9 3.5 10.7 11.3 12.7 12.4 10.7 9.3 10.7 10.4 10.9 10.0 10.7 11.2 5.3 9.6 22.3 12.7 14.0 9.2 5.3 8.3 25.6 20.1 8.9 7.5 7.4 8.6 8.2 1.8 37.5 8.5 10.4 19.3 5.9 8.6 9.7 11.2 9.8 9.2 12.0 16.4 21.3 6.7 6.1 9.8 23.4 6.9 13.3 12.0 7.9 13.1 8.9 32.0 17.8 16.6 10.2 9.7 5.5 6.1 12.5 7.9 1.8 5.6 11.6 10.9 13.4 17.6 23.8 10.7 13.5 14.7 14.3 5.4 17.3 6.9 25.4 23.5 6.6 11.1 7.7 0.6 2.9 21.0 4.7 8.1 9.5 13.6 15.4 6.0 KIAA0930 "bK268H5.C22.1, C22orf9" ENSG00000100364 KIAA0930 Q6ICG6 22 45192244-45240894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 211.9" "Cell type enhanced" "Detected in many" "Astrocytes: 132.2;Excitatory neurons: 139.6;Oligodendrocytes: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 11.0;eosinophil: 8.6;intermediate monocyte: 13.9;myeloid DC: 12.1;non-classical monocyte: 17.3;plasmacytoid DC: 10.0" "Group enriched" "Detected in all" 5 "dendritic cells: 12.1;granulocytes: 8.6;monocytes: 17.3" "Cell line enhanced" "Detected in many" "THP-1: 327.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038091 Uncertain Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" Nucleoplasm "HPA038091: AB_10675627" "unprognostic (4.16e-2)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "prognostic favorable (9.22e-5)" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (6.90e-8)" "unprognostic (2.80e-1)" "unprognostic (2.03e-1)" "unprognostic (3.58e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-1)" "prognostic unfavorable (8.95e-7)" "unprognostic (6.89e-3)" "unprognostic (5.32e-2)" "unprognostic (5.58e-2)" "unprognostic (1.15e-1)" 33.9 58.3 195.7 27.7 209.3 24.7 25.9 163.3 211.9 46.0 130.3 29.4 14.6 24.0 40.4 34.5 18.2 16.0 18.1 184.1 189.1 23.8 48.4 24.8 29.0 182.8 192.6 13.6 20.1 18.5 19.2 12.0 179.8 29.1 11.2 3.5 26.7 24.7 33.8 64.0 21.4 15.2 170.4 38.7 18.6 26.2 193.6 20.4 18.4 13.1 22.3 44.0 35.6 210.3 49.6 31.5 19.1 38.3 64.1 30.2 19.2 26.9 26.8 28.2 24.1 29.5 26.5 33.2 39.2 42.8 22.5 54.5 29.5 118.6 10.7 35.6 46.4 0.1 42.0 34.3 25.7 89.4 19.7 17.1 59.2 27.3 45.3 21.5 26.8 23.9 11.7 53.1 17.4 56.9 40.0 82.8 18.9 35.8 26.5 48.1 12.9 110.7 42.6 29.7 15.9 28.4 42.5 57.6 75.5 36.8 28.1 327.8 36.5 29.0 50.6 39.7 15.7 44.9 32.9 32.1 34.0 133.7 30.3 0.8 11.0 8.6 2.3 13.9 1.6 2.3 0.9 2.6 12.1 1.8 0.9 1.6 2.5 1.9 17.3 10.0 2.0 3.7 195.7 209.3 163.3 211.9 184.1 189.1 182.8 192.6 179.8 170.4 193.6 210.3 11.4 6.4 8.8 132.2 9.9 52.8 18.6 22.7 6.8 7.3 13.9 13.5 11.5 12.8 11.8 18.4 6.2 2.0 24.9 16.2 0.0 18.6 2.9 11.6 9.3 9.7 10.7 23.1 139.6 20.7 6.5 32.7 4.6 19.5 2.5 3.8 17.5 23.3 67.5 5.0 56.7 10.0 14.2 71.1 50.0 10.8 10.8 59.8 44.4 24.4 68.5 6.5 13.4 16.1 152.9 18.0 13.7 14.7 11.2 25.6 15.7 13.8 9.3 5.9 0.0 10.2 10.9 7.5 4.4 15.2 57.3 2.7 9.3 5.3 12.8 23.1 KTI12 "MGC20419, SBBI81, TOT4" ENSG00000198841 "KTI12 chromatin associated homolog" Q96EK9 1 52032103-52033810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031203, HPA031204, HPA031205" Approved Approved "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles, Cytoplasmic bodies" "HPA031203: AB_2732464, HPA031204: AB_10600110, HPA031205: AB_10611380" "unprognostic (6.14e-2)" "unprognostic (9.45e-2)" "unprognostic (1.19e-3)" "unprognostic (3.36e-3)" "unprognostic (4.18e-1)" "unprognostic (1.83e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (1.74e-1)" "unprognostic (2.94e-1)" "unprognostic (3.72e-2)" "unprognostic (4.06e-2)" "unprognostic (8.08e-3)" "unprognostic (6.59e-2)" "unprognostic (3.36e-3)" "unprognostic (2.39e-1)" "unprognostic (3.59e-2)" "unprognostic (1.64e-2)" 7.5 10.2 4.2 6.9 4.0 16.7 5.9 4.5 4.4 4.5 4.9 6.5 4.9 7.3 4.7 5.8 6.9 3.8 5.1 4.0 5.0 4.9 6.8 4.2 8.7 4.5 4.1 9.2 6.8 3.9 6.4 4.2 4.1 4.0 4.0 2.5 4.0 4.7 4.6 5.5 7.6 4.7 4.1 8.5 7.1 7.2 4.9 6.6 4.0 3.5 7.6 5.5 3.8 4.4 14.0 13.4 5.3 12.5 17.8 14.8 16.6 13.9 17.0 20.1 17.1 15.2 6.7 16.0 15.3 14.5 29.8 15.6 18.7 16.4 13.9 16.5 20.9 16.6 14.6 14.9 12.3 23.8 15.7 13.9 12.5 16.0 8.6 8.7 13.8 14.0 25.2 7.7 17.1 11.1 17.5 26.7 10.3 12.2 14.9 16.3 14.6 21.5 19.4 10.0 9.3 13.5 13.4 23.3 25.8 12.0 4.5 37.2 10.4 16.2 10.1 19.4 26.3 28.6 25.8 25.4 17.9 25.2 12.1 17.0 21.6 16.4 22.1 24.5 24.9 29.8 24.7 27.0 29.4 22.7 29.0 20.7 4.5 24.2 19.3 44.6 26.9 18.8 4.2 4.0 4.5 4.4 4.0 5.0 4.5 4.1 4.1 4.1 4.9 4.4 10.8 3.2 5.1 0.0 14.3 7.1 13.2 14.1 5.7 6.1 5.3 6.1 3.1 8.6 6.3 3.7 0.0 12.1 17.5 1.8 5.9 11.3 2.3 4.4 10.6 8.4 2.4 8.6 0.0 10.9 17.0 8.6 3.1 3.9 6.3 26.3 9.3 5.9 10.0 10.1 0.0 3.9 6.1 6.6 6.4 1.2 11.5 6.0 5.4 0.0 13.6 9.7 10.3 0.0 0.0 10.5 3.4 10.1 9.5 7.8 3.1 11.6 4.7 4.9 19.7 8.1 10.7 20.3 9.3 6.7 7.4 18.3 10.6 28.1 4.7 11.5 LAIR1 CD305 ENSG00000167613 "Leukocyte associated immunoglobulin like receptor 1" Q6GTX8 19 54351384-54370558 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.1;lymphoid tissue: 46.3" "Cell type enhanced" "Detected in many" "dendritic cells: 106.6;granulocytes: 109.3;Hofbauer cells: 190.9;Kupffer cells: 100.9;Macrophages: 128.9;NK-cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 7.5;Karpas-707: 19.4;THP-1: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011155 Enhanced Supported "Plasma membrane" NA NA 350000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA011155: AB_1852685" "unprognostic (1.91e-1)" "unprognostic (1.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.25e-2)" "unprognostic (2.03e-2)" "unprognostic (4.38e-2)" "unprognostic (2.16e-2)" "unprognostic (1.74e-1)" "unprognostic (5.00e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.01e-5)" "unprognostic (1.72e-1)" "unprognostic (2.72e-3)" "unprognostic (3.52e-2)" "unprognostic (5.22e-2)" 23.3 11.6 0.5 3.0 0.3 4.4 12.3 1.6 1.3 4.1 0.5 6.9 0.4 3.8 0.2 2.6 5.5 0.9 3.8 0.4 0.6 4.6 3.5 28.1 5.8 1.0 0.8 2.2 3.8 0.1 4.4 1.0 1.0 5.4 0.2 0.1 5.8 0.2 1.3 2.1 14.3 2.0 0.4 46.3 5.0 1.7 1.1 3.9 3.3 0.1 0.9 6.3 3.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 3.3 7.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 19.4 0.0 0.0 2.6 1.8 0.0 0.0 0.0 2.6 0.2 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 22.9 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 3.2 0.3 13.1 4.2 11.7 7.7 9.8 4.8 2.1 2.3 4.1 0.1 5.8 3.4 4.4 0.7 6.3 11.0 11.2 1.7 3.8 0.5 0.3 1.6 1.3 0.4 0.6 1.0 0.8 1.0 0.4 1.1 0.9 1.9 16.0 25.6 0.3 26.1 0.6 0.6 0.2 0.0 5.6 1.1 2.9 1.5 1.5 11.2 0.0 37.5 5.3 106.6 0.2 0.0 0.1 32.2 0.6 0.7 5.0 0.0 10.9 0.4 0.0 5.2 2.5 0.0 0.7 109.3 0.6 3.6 1.2 190.9 1.7 0.5 0.0 0.0 100.9 17.7 26.1 0.3 128.9 0.0 13.1 22.5 0.9 98.9 0.0 0.6 0.1 0.0 0.0 5.1 0.7 0.3 0.3 11.0 15.4 0.0 0.9 1.3 2.9 1.0 0.4 1.1 10.0 32.1 0.2 0.2 0.9 LAMP2 CD107b ENSG00000005893 "Lysosomal associated membrane protein 2" P13473 X 120426148-120469365 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Autophagy "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 507.2;Syncytiotrophoblasts: 402.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 556.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 556.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005272, HPA029100" Supported Supported Vesicles NA NA 520000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB005272: AB_647855, HPA029100: AB_10795022" "unprognostic (2.99e-3)" "unprognostic (5.26e-2)" "unprognostic (2.66e-3)" "unprognostic (1.74e-1)" "unprognostic (3.10e-1)" "unprognostic (2.50e-2)" "unprognostic (4.84e-1)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (9.73e-2)" "unprognostic (1.11e-2)" "unprognostic (2.50e-2)" "unprognostic (2.85e-1)" "unprognostic (6.78e-2)" "unprognostic (2.66e-1)" "unprognostic (5.53e-3)" 54.2 68.7 80.3 38.3 144.2 62.8 56.3 109.1 135.5 64.9 52.7 39.2 44.3 44.3 55.1 79.4 44.1 69.6 45.3 81.6 101.8 85.5 129.9 54.2 34.1 113.0 112.6 49.1 57.8 64.2 32.2 47.9 120.6 62.2 35.0 32.6 102.1 55.1 111.6 67.2 42.4 42.8 100.5 39.5 51.8 26.2 100.9 59.3 61.7 67.4 36.6 43.4 63.3 211.7 53.8 47.5 40.1 49.7 367.0 140.9 91.5 79.3 130.4 77.1 134.4 42.7 90.3 47.9 73.1 132.7 236.2 84.9 56.7 67.2 125.5 43.6 37.2 35.8 46.4 54.3 148.1 158.9 73.2 151.5 114.8 108.1 75.1 188.6 107.5 32.5 42.1 122.9 117.2 79.3 45.3 80.2 29.0 63.7 42.6 35.1 65.3 73.1 102.3 36.9 14.0 22.6 99.7 93.0 196.5 57.4 64.7 173.0 122.5 114.1 58.7 176.2 261.5 68.5 78.6 30.2 131.4 182.4 284.4 30.6 114.9 224.1 27.1 97.1 20.6 17.1 24.3 24.5 64.2 22.5 23.4 21.8 556.6 31.8 96.2 33.4 33.4 66.3 80.3 144.2 109.1 135.5 81.6 101.8 113.0 112.6 120.6 100.5 100.9 211.7 75.7 73.7 53.8 52.2 29.8 100.9 92.5 262.7 64.9 17.6 74.0 58.3 37.3 173.0 155.3 66.2 14.6 163.7 44.3 52.1 39.2 217.7 3.3 103.4 74.1 69.9 36.6 14.1 32.4 70.6 128.3 113.7 38.7 168.1 17.7 46.7 87.8 176.8 208.0 18.5 40.7 32.6 134.3 133.1 80.4 8.6 113.7 135.5 131.6 33.7 132.7 116.3 50.4 57.3 507.2 62.5 54.4 109.9 66.6 100.8 97.5 154.7 75.6 11.5 39.5 176.8 61.7 6.4 13.7 78.8 136.2 402.4 34.5 71.0 34.8 92.9 LAMTOR2 "ENDAP, MAPBPIP, MAPKSP1AP, p14, Ragulator2, ROBLD3" ENSG00000116586 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2" Q9Y2Q5 1 156054782-156058506 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 627.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004126 Approved Approved Nucleoplasm,Vesicles No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Vesicles" "HPA004126: AB_1849916" "unprognostic (2.09e-1)" "unprognostic (1.23e-1)" "unprognostic (2.07e-1)" "unprognostic (1.58e-1)" "unprognostic (8.14e-2)" "unprognostic (4.52e-2)" "unprognostic (8.64e-2)" "unprognostic (3.90e-2)" "unprognostic (3.79e-1)" "unprognostic (1.66e-2)" "unprognostic (2.06e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (1.10e-6)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (8.65e-2)" "unprognostic (1.35e-1)" 64.3 84.4 81.9 41.6 81.4 57.1 57.7 83.9 98.9 44.8 83.0 62.0 51.5 42.3 76.7 75.2 52.1 43.8 96.1 81.6 84.7 91.0 164.3 53.8 56.3 81.6 82.5 26.7 87.8 74.4 44.6 37.5 82.0 50.9 56.5 18.0 59.3 44.0 88.6 57.8 53.7 48.9 82.2 65.7 78.1 26.6 85.8 56.1 44.7 70.2 52.0 53.6 46.7 85.8 63.9 142.3 65.4 90.9 131.9 106.7 72.3 55.7 94.4 68.8 78.1 65.9 106.1 94.0 94.4 108.7 60.0 91.5 67.7 151.1 38.7 78.4 103.0 54.9 96.2 88.6 104.4 78.0 86.5 126.1 93.4 73.1 93.3 94.4 142.6 137.3 50.8 68.1 100.9 128.7 80.6 111.4 69.4 250.9 212.1 67.5 48.7 138.7 152.5 93.2 25.3 145.3 70.4 195.1 116.3 104.1 136.5 227.9 96.6 57.5 52.4 83.4 53.0 101.6 166.5 56.2 102.2 87.3 62.9 281.8 465.8 376.2 172.2 446.9 169.8 290.6 188.2 188.7 537.2 249.4 142.6 152.8 231.8 207.0 363.2 284.1 298.3 389.7 81.9 81.4 83.9 98.9 81.6 84.7 81.6 82.5 82.0 82.2 85.8 85.8 102.5 57.7 46.5 3.6 64.5 48.4 59.5 190.3 43.3 29.4 129.9 123.2 113.5 114.4 120.2 108.5 6.2 146.3 73.9 247.5 387.4 193.0 44.5 113.2 78.7 92.6 126.1 48.0 4.5 179.3 203.1 67.5 68.3 105.0 107.3 56.7 86.7 322.1 416.1 6.7 5.4 164.7 197.4 188.9 150.1 89.0 47.2 165.0 158.3 5.6 297.4 92.8 94.7 4.5 5.8 183.2 267.4 50.8 76.8 80.2 317.8 627.2 144.1 30.5 32.9 38.9 124.6 25.5 33.9 99.4 80.0 77.2 64.2 83.3 166.9 97.7 LAT2 "HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5" ENSG00000086730 "Linker for activation of T cells family member 2" Q9GZY6 7 74199652-74229834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.3;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "B-cells: 90.6;granulocytes: 171.6;Hofbauer cells: 82.7;Kupffer cells: 71.1;Langerhans cells: 81.9;Macrophages: 89.1;monocytes: 89.6;NK-cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 871.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 192.2;REH: 205.7;RPMI-8226: 73.3;THP-1: 186.5;U-937: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003462 Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA003462: AB_1079238" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (1.32e-2)" "unprognostic (3.55e-3)" "unprognostic (1.09e-1)" "unprognostic (3.30e-3)" "unprognostic (2.79e-2)" "unprognostic (1.33e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (6.34e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" 6.8 5.4 9.7 37.7 11.1 61.3 3.8 11.8 12.8 3.7 9.1 6.5 6.3 2.9 2.5 3.6 4.2 9.1 2.3 10.3 12.2 3.3 4.8 19.2 51.6 18.4 13.6 1.7 3.0 2.2 3.0 7.4 17.7 7.1 7.7 1.2 4.5 3.5 3.3 3.0 13.6 8.8 16.5 47.0 6.5 2.0 15.3 12.2 2.8 2.4 56.6 10.1 2.5 20.1 1.7 1.1 1.1 3.1 0.3 0.0 1.1 1.4 1.2 0.6 0.7 2.3 28.9 19.6 0.4 0.5 6.1 1.2 0.4 1.1 0.6 31.4 1.2 8.6 1.8 1.8 0.1 56.1 55.6 0.4 0.8 2.1 0.6 1.2 0.3 1.1 1.6 9.3 0.5 1.7 1.3 192.2 0.9 5.5 2.0 205.7 1.1 73.3 0.2 1.7 0.9 0.8 0.6 1.2 1.2 0.9 1.1 186.5 2.1 2.1 19.9 0.8 1.8 0.9 6.2 32.2 9.4 177.6 1.5 871.6 276.6 46.0 8.8 159.0 0.9 169.3 2.3 1.4 225.2 191.1 1.0 2.9 491.0 73.9 93.9 8.9 4.9 214.7 9.7 11.1 11.8 12.8 10.3 12.2 18.4 13.6 17.7 16.5 15.3 20.1 1.3 3.2 16.2 0.7 90.6 3.4 0.7 0.0 0.6 0.3 1.0 1.9 1.1 5.7 3.1 3.7 0.0 0.6 47.8 0.2 0.0 0.3 2.4 1.3 0.6 3.9 7.8 16.6 1.7 0.2 1.1 1.7 1.1 2.1 171.6 0.4 3.9 4.5 82.7 0.0 1.4 0.8 0.0 71.1 81.9 3.4 0.0 89.1 1.8 20.6 89.6 0.2 70.0 0.5 0.9 0.6 0.1 0.7 18.7 1.2 0.1 0.2 5.9 1.3 0.0 1.9 0.9 0.4 1.4 0.1 2.6 1.2 27.7 0.3 0.8 0.4 LPO SPO ENSG00000167419 Lactoperoxidase P22079 17 58218548-58268518 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Antimicrobial, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 404 "salivary gland: 1026.8" "Group enriched" "Detected in some" 6 "Breast glandular cells: 25.2;Early spermatids: 8.3;Late spermatids: 14.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "midbrain: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "THP-1: 9.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA028688 Enhanced Supported "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 43: THP-1 - Innate immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA028688: AB_10601909" "unprognostic (2.74e-1)" "unprognostic (5.12e-2)" "unprognostic (4.14e-3)" "unprognostic (1.56e-3)" "unprognostic (2.41e-2)" "unprognostic (9.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (2.40e-2)" "unprognostic (6.27e-3)" "unprognostic (6.32e-2)" "unprognostic (2.56e-1)" "unprognostic (0.00e+0)" "unprognostic (3.41e-2)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (1.22e-1)" 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1026.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 2.5 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.7 25.2 0.5 0.7 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 8.3 0.3 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 1.3 0.0 0.4 0.0 0.2 1.7 0.3 0.0 0.0 0.0 0.0 14.1 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.5 1.4 0.1 0.0 0.3 0.0 0.2 0.1 2.6 0.4 0.0 0.3 0.0 0.2 0.0 0.5 0.5 LRP3 "hLRp105, LRP-3" ENSG00000130881 "LDL receptor related protein 3" O75074 19 33177603-33208864 "Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.2;Muller glia cells: 29.9;Peritubular cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "THP-1: 61.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041658 Approved "Lipid droplets" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Lipid droplets" "HPA041658: " "unprognostic (3.10e-1)" "unprognostic (2.55e-2)" "unprognostic (3.25e-2)" "unprognostic (1.45e-2)" "unprognostic (2.38e-2)" "unprognostic (1.80e-1)" "unprognostic (1.39e-1)" "unprognostic (3.14e-2)" "unprognostic (3.07e-2)" "unprognostic (4.67e-2)" "prognostic favorable (6.12e-7)" "unprognostic (1.34e-1)" "unprognostic (2.71e-3)" "unprognostic (4.36e-1)" "unprognostic (2.85e-2)" "unprognostic (2.40e-1)" "unprognostic (1.32e-1)" 28.1 28.2 44.7 5.1 47.2 18.7 23.8 15.2 61.2 27.0 0.0 25.7 7.1 27.0 8.5 8.5 21.4 8.4 19.1 53.2 22.6 11.0 39.3 13.0 2.6 21.4 25.8 69.8 17.6 16.7 26.9 3.5 20.8 25.9 3.0 2.4 16.8 12.0 28.7 14.2 10.2 10.3 17.0 6.8 17.3 8.6 31.6 1.7 20.4 17.6 0.9 24.3 15.6 25.7 0.1 48.6 13.1 47.9 32.2 12.1 9.0 12.4 12.0 11.1 4.3 14.0 0.6 0.0 31.6 15.4 16.0 0.0 12.6 1.3 0.9 0.2 23.8 0.0 10.7 49.1 12.3 17.8 1.6 18.2 11.1 3.1 1.7 1.9 9.3 0.0 0.1 0.0 14.4 45.2 0.1 19.6 27.0 9.7 2.0 0.0 6.0 0.1 0.0 19.4 28.8 43.3 20.0 0.1 3.5 1.4 20.0 61.5 0.0 23.5 20.4 35.6 7.1 0.0 0.0 0.2 0.0 30.0 7.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.1 44.7 47.2 15.2 61.2 53.2 22.6 21.4 25.8 20.8 17.0 31.6 25.7 4.4 0.0 3.6 18.9 1.1 3.3 2.6 1.4 4.0 30.2 12.8 13.7 0.5 14.3 3.5 5.5 4.2 0.2 0.4 1.3 0.0 5.8 2.7 5.4 17.6 3.0 1.8 5.7 19.5 7.8 0.7 24.9 0.5 10.7 0.0 19.2 6.1 28.3 10.3 23.5 19.4 6.4 0.0 8.8 2.7 6.4 26.1 5.0 3.6 4.7 5.8 29.9 0.0 15.1 1.7 5.9 1.0 32.7 0.1 8.2 0.7 0.6 0.3 4.2 6.6 6.8 13.7 0.2 2.8 2.3 2.6 0.0 0.6 9.8 6.0 1.9 LRRC37A2 FLJ45049 ENSG00000238083 "Leucine rich repeat containing 37 member A2" A6NM11 17 46511511-46555650 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 6.5" "Cell type enhanced" "Detected in many" "Astrocytes: 34.0;Early spermatids: 46.8;Excitatory neurons: 55.9;Inhibitory neurons: 55.5;Microglial cells: 34.7;Oligodendrocyte precursor cells: 47.7;Oligodendrocytes: 46.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.3;THP-1: 1.2" "HPA042121, HPA043056, HPA045090, HPA049080" Supported Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA042121: AB_2677858, HPA043056: AB_2678294, HPA045090: AB_2679211, HPA049080: AB_2680624" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "unprognostic (8.96e-2)" "unprognostic (6.35e-2)" "unprognostic (2.53e-1)" "unprognostic (2.97e-3)" "unprognostic (4.61e-3)" "unprognostic (1.63e-1)" "unprognostic (6.47e-2)" "unprognostic (2.01e-1)" "unprognostic (1.55e-3)" "unprognostic (8.00e-2)" "unprognostic (3.02e-7)" "unprognostic (8.40e-2)" "unprognostic (2.82e-1)" "unprognostic (1.52e-1)" "unprognostic (5.77e-2)" 0.5 0.1 0.2 0.2 0.2 0.5 0.5 0.8 0.2 0.3 0.1 0.3 0.0 0.3 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.6 0.1 0.3 0.2 0.4 0.1 0.2 0.2 0.4 0.7 0.0 0.3 0.3 0.3 0.4 0.2 0.3 0.6 0.6 0.4 0.2 0.0 0.1 0.2 6.5 0.4 0.4 0.3 0.2 0.2 0.4 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.4 1.2 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.1 0.0 0.3 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.2 0.1 0.1 0.4 0.1 0.3 0.0 0.4 0.0 2.5 22.4 14.6 34.0 3.8 1.5 4.2 1.0 2.2 7.1 2.6 2.2 2.5 1.5 5.1 0.0 12.5 1.1 8.5 2.3 0.0 2.6 46.8 8.3 5.6 3.0 1.8 0.8 55.9 0.9 0.9 3.2 1.5 5.5 11.4 5.4 1.4 0.8 1.4 13.5 55.5 2.5 0.0 1.2 1.8 11.5 3.4 3.5 0.0 34.7 1.8 2.4 3.1 47.7 46.4 1.0 2.7 1.9 3.0 2.5 1.2 0.4 11.3 8.8 13.1 4.1 2.7 7.9 3.0 1.4 2.3 0.7 6.1 1.7 1.6 2.9 LRRC8C AD158 ENSG00000171488 "Leucine rich repeat containing 8 VRAC subunit C" Q8TDW0 1 89633072-89769903 "Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 73.5;Excitatory neurons: 73.6;Inhibitory neurons: 99.2;Microglial cells: 185.5;Oligodendrocytes: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.9;monocytes: 6.6;T-cells: 11.3" "Cell line enhanced" "Detected in many" "THP-1: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029347 Uncertain Approved "Golgi apparatus" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 28: Placenta - Pregnancy" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA029347: AB_10601544" "unprognostic (2.61e-2)" "unprognostic (3.09e-2)" "unprognostic (3.83e-2)" "unprognostic (1.76e-2)" "unprognostic (3.32e-2)" "unprognostic (1.65e-2)" "unprognostic (5.02e-2)" "unprognostic (3.76e-3)" "unprognostic (4.28e-2)" "unprognostic (4.90e-3)" "unprognostic (5.32e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (2.78e-2)" "unprognostic (4.42e-2)" "unprognostic (1.94e-2)" "unprognostic (3.38e-2)" 14.3 7.6 3.8 9.0 4.5 8.0 7.7 4.5 5.8 3.2 11.4 3.2 3.2 7.3 1.9 2.9 2.8 6.6 6.2 4.1 4.1 2.5 3.3 7.7 12.2 4.6 5.0 5.3 1.8 2.8 2.3 6.6 5.1 2.3 3.7 1.6 2.0 2.0 2.7 6.0 3.8 15.8 4.8 9.2 2.9 4.0 4.7 5.6 3.5 8.0 7.7 6.2 2.0 6.0 0.3 3.8 3.0 2.7 9.1 10.2 1.4 19.3 21.6 8.7 8.0 0.0 1.3 6.0 5.3 8.5 14.9 13.1 10.1 29.0 20.9 14.8 6.1 5.7 2.9 0.3 7.4 26.6 1.9 4.4 5.8 18.8 10.0 5.8 35.6 9.2 3.9 7.9 7.5 0.7 3.9 26.2 3.3 0.1 7.8 26.5 1.4 2.0 1.8 3.2 2.3 10.7 7.1 0.7 16.2 4.7 0.2 41.3 29.9 15.3 7.3 5.3 14.9 2.9 2.6 3.1 4.7 19.6 2.6 0.4 6.0 0.0 3.8 5.2 3.3 0.7 6.1 5.1 8.9 0.5 4.8 4.5 0.8 2.0 6.6 0.7 11.3 3.2 3.8 4.5 4.5 5.8 4.1 4.1 4.6 5.0 5.1 4.8 4.7 6.0 73.5 3.2 3.6 31.3 7.6 45.4 3.8 5.6 3.4 2.3 1.7 2.9 6.3 2.8 2.7 0.0 0.0 0.1 24.6 0.3 0.0 1.7 36.3 0.2 1.9 47.3 1.2 4.8 73.6 2.4 1.1 8.7 2.6 0.6 0.0 58.5 28.9 0.1 13.6 1.7 99.2 0.3 2.0 29.5 36.9 21.3 0.0 27.8 26.6 185.5 21.3 0.5 13.4 22.1 85.2 12.8 1.9 0.7 20.8 2.1 0.3 0.6 2.9 1.2 0.0 2.2 24.2 3.9 2.0 1.3 44.9 0.3 27.1 3.4 0.3 2.5 LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Group enriched" "Detected in many" 11 "Hofbauer cells: 407.1;Kupffer cells: 1326.9;Langerhans cells: 1240.5;Macrophages: 871.6;monocytes: 1096.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 39.3;HMC-1: 73.6;MOLT-4: 39.6;NB-4: 76.2;THP-1: 179.9;U-937: 92.9" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" 15.2 10.2 4.3 22.0 4.3 100.3 7.9 4.6 7.2 5.6 5.0 7.9 7.1 3.7 1.4 5.5 6.6 3.1 7.6 4.6 5.5 10.8 14.4 48.8 13.8 6.1 4.9 3.0 4.7 0.9 6.1 4.7 6.6 8.9 3.0 0.5 6.9 2.3 2.1 7.8 15.0 5.1 5.4 181.9 5.7 1.8 5.2 15.1 4.6 1.9 7.1 9.1 5.1 6.0 0.3 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 2.5 0.6 0.0 0.0 0.5 0.3 0.4 0.3 12.9 0.0 39.3 0.0 0.0 0.7 29.3 73.6 0.0 0.3 0.1 1.2 0.3 0.9 0.8 0.1 0.2 0.0 0.0 39.6 76.2 0.1 0.0 0.0 18.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 179.9 0.3 0.0 0.4 0.0 0.2 0.1 0.0 5.9 0.0 92.9 0.0 112.2 419.7 681.6 9.4 1273.9 80.7 32.8 15.9 20.2 392.9 21.9 10.9 9.0 1133.0 21.6 1746.7 69.9 12.0 541.6 4.3 4.3 4.6 7.2 4.6 5.5 6.1 4.9 6.6 5.4 5.2 6.0 5.4 35.3 86.7 0.7 43.7 35.2 0.3 0.2 0.0 0.3 3.2 12.2 1.9 7.2 13.0 11.0 0.0 2.9 42.8 1.0 0.0 0.6 1.5 0.4 1.9 12.9 0.0 15.1 0.2 0.2 3.8 9.2 1.5 0.4 70.3 0.1 22.9 5.8 407.1 0.0 0.3 0.0 2.0 1326.9 1240.5 5.4 3.7 871.6 44.4 24.4 1096.6 0.7 60.8 0.5 0.1 0.1 1.1 1.2 4.7 1.0 0.0 3.8 11.0 0.2 26.3 2.2 2.8 2.4 4.6 0.4 28.3 5.3 43.6 0.0 0.4 0.3 LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503637-41513887 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.2;lung: 15.1;salivary gland: 11.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 25.3;Gastric mucus-secreting cells: 18.8;Hepatic stellate cells: 11.4;Intestinal goblet cells: 7.9;Proximal enterocytes: 15.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "MAIT T-cell: 5.7;plasmacytoid DC: 5.0" "Group enriched" "Detected in many" 10 "dendritic cells: 5.0;T-cells: 5.7" "Cell line enhanced" "Detected in some" "HEL: 5.0;NB-4: 9.7;RH-30: 4.6;THP-1: 14.7" "Low region specificity" "Detected in many" HPA059545 Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA059545: AB_2684057" "unprognostic (9.47e-4)" "unprognostic (5.52e-4)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-1)" "unprognostic (5.65e-3)" "unprognostic (1.74e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.81e-3)" "unprognostic (9.36e-3)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" 0.8 0.6 1.0 1.4 1.6 4.6 0.5 1.2 1.8 0.9 0.6 5.2 12.5 0.2 0.0 0.3 0.4 2.4 1.7 1.3 0.7 4.0 2.9 15.1 1.2 0.6 0.6 0.1 0.3 0.6 0.7 10.4 0.7 0.4 5.7 0.1 11.8 0.3 1.8 1.4 13.2 0.3 0.6 5.5 9.9 2.5 0.8 0.4 0.7 0.0 2.1 0.7 0.7 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.6 0.8 1.2 2.2 0.0 0.0 0.0 0.6 0.0 0.0 2.6 0.0 0.4 0.2 1.3 5.0 0.1 0.0 2.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 1.9 0.0 1.8 0.0 0.0 9.7 0.4 1.8 0.2 0.2 4.6 0.1 0.0 0.0 0.4 2.9 0.1 0.2 0.0 2.6 0.2 14.7 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.8 0.0 0.0 0.0 0.4 0.0 5.7 0.5 0.3 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 1.0 1.6 1.2 1.8 1.3 0.7 0.6 0.6 0.7 0.6 0.8 0.9 0.3 0.0 0.0 0.3 1.6 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.8 2.8 0.9 0.0 0.0 0.3 5.5 25.3 0.0 0.0 2.8 0.1 0.4 1.8 1.8 3.2 2.9 0.2 1.5 0.2 18.8 0.2 0.0 0.3 11.4 0.5 0.1 0.0 0.2 7.9 0.0 1.9 0.6 2.1 0.0 0.4 3.6 0.0 0.4 0.0 1.0 0.5 0.4 0.7 5.5 0.0 2.7 0.0 15.3 0.0 5.6 0.0 0.0 0.3 0.5 2.2 1.2 0.0 0.1 0.4 4.0 0.0 3.8 0.0 LYST "CHS, CHS1" ENSG00000143669 "Lysosomal trafficking regulator" Q99698 1 235661041-235883640 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Phagocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.3;retina: 27.9" "Cell type enhanced" "Detected in all" "monocytes: 277.4" "Cancer enhanced" "Detected in all" "melanoma: 11.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in many" 5 "granulocytes: 12.2;monocytes: 6.1" "Cell line enhanced" "Detected in many" "HDLM-2: 30.8;SK-MEL-30: 27.1;THP-1: 99.5;U-937: 38.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053366, HPA055725" Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane, Centriolar satellite" "HPA053366: AB_2682129, HPA055725: AB_2682898" "unprognostic (1.56e-2)" "unprognostic (1.54e-1)" "unprognostic (9.92e-2)" "unprognostic (8.85e-2)" "unprognostic (1.96e-2)" "unprognostic (4.32e-2)" "unprognostic (4.11e-2)" "unprognostic (7.79e-2)" "unprognostic (4.08e-2)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.59e-1)" "unprognostic (1.54e-1)" "unprognostic (6.29e-2)" "unprognostic (1.99e-1)" 5.2 2.7 2.0 8.5 2.7 31.3 6.4 10.1 3.3 7.1 9.1 4.5 3.0 4.3 2.7 4.2 3.9 5.1 2.2 2.0 2.5 3.6 5.5 5.5 7.5 2.2 2.6 4.5 2.2 6.2 1.8 4.6 2.5 3.4 4.3 27.9 4.3 3.3 1.7 9.7 3.3 4.4 1.1 10.8 7.7 6.1 3.3 25.7 6.4 3.8 6.5 5.7 5.2 3.4 8.6 1.9 0.9 2.0 12.7 14.4 1.3 3.1 12.5 3.3 3.1 0.0 2.3 1.1 1.2 6.8 7.7 4.1 1.2 1.6 2.9 30.8 2.7 2.8 1.9 0.6 2.3 4.2 3.7 4.8 7.8 4.0 10.0 4.8 2.8 1.3 0.2 1.7 2.6 0.4 5.3 8.7 0.2 1.6 0.9 0.4 1.2 0.0 9.2 9.2 5.4 1.1 3.4 0.2 27.1 1.0 1.2 99.5 5.8 2.4 1.1 2.8 2.8 2.1 0.1 0.2 4.1 38.0 7.0 0.4 2.9 5.7 0.6 3.4 0.8 1.0 0.2 0.7 1.7 1.4 0.2 0.4 12.2 1.7 6.1 0.2 0.2 0.7 2.0 2.7 10.1 3.3 2.0 2.5 2.2 2.6 2.5 1.1 3.3 3.4 66.3 19.2 41.1 71.2 70.9 71.0 89.8 14.6 18.8 67.4 17.6 15.6 11.6 15.7 28.4 11.0 93.8 6.7 77.3 25.0 11.7 6.6 24.6 22.6 23.8 51.2 9.6 21.0 151.5 12.3 5.0 27.0 41.3 22.4 112.5 9.4 26.0 15.4 31.9 52.2 155.9 14.3 28.5 65.6 81.3 17.7 28.0 111.4 120.9 159.3 277.4 25.6 88.6 112.1 81.6 39.6 24.2 21.8 37.3 56.0 12.7 10.9 26.7 162.5 13.1 31.2 22.7 93.3 28.0 18.7 65.1 8.8 71.3 13.6 7.6 98.5 MAFG "MGC13090, MGC20149" ENSG00000197063 "MAF bZIP transcription factor G" O15525 17 81918270-81927735 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 12.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 12.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025573 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" "CAB025573: " "unprognostic (4.42e-2)" "unprognostic (1.50e-1)" "unprognostic (3.11e-1)" "prognostic unfavorable (5.82e-4)" "unprognostic (3.00e-2)" "unprognostic (8.72e-2)" "prognostic unfavorable (1.90e-6)" "unprognostic (9.77e-3)" "unprognostic (1.27e-1)" "unprognostic (8.05e-2)" "unprognostic (5.97e-3)" "unprognostic (4.91e-2)" "unprognostic (7.46e-2)" "unprognostic (2.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.97e-2)" "unprognostic (4.54e-3)" 13.5 12.9 24.3 9.8 23.3 40.6 9.6 18.5 26.3 11.1 13.6 17.7 11.1 15.3 5.0 19.2 13.4 10.7 18.6 25.3 26.7 13.0 11.0 22.1 8.0 26.9 28.4 14.0 10.0 13.6 13.0 8.2 33.5 11.6 6.8 4.9 10.5 9.5 44.9 11.8 14.9 10.8 21.3 15.5 15.2 14.0 27.1 7.1 14.6 19.7 6.7 18.3 11.4 21.7 18.2 61.2 13.0 12.9 22.5 17.1 23.1 20.6 21.8 17.2 15.9 20.1 30.7 8.1 20.6 16.0 52.4 21.1 13.9 9.7 11.4 14.3 18.5 37.1 85.5 25.8 33.9 33.4 61.8 14.1 20.7 24.1 22.2 26.9 21.2 16.9 49.9 38.8 17.3 8.0 15.9 37.4 15.6 37.7 21.2 19.9 20.6 15.0 7.6 18.7 22.4 26.7 15.1 18.9 47.1 21.8 8.0 91.0 26.3 37.6 29.9 32.1 27.7 27.2 18.2 12.7 31.0 35.7 49.8 12.2 2.8 1.5 0.2 0.9 0.4 0.7 0.3 0.0 2.3 0.4 0.2 0.3 3.2 0.3 1.1 1.7 0.3 1.2 24.3 23.3 18.5 26.3 25.3 26.7 26.9 28.4 33.5 21.3 27.1 21.7 33.4 22.4 9.8 19.2 19.8 74.4 108.5 12.6 27.3 29.4 63.0 33.8 18.0 32.9 12.4 11.0 22.9 8.8 12.0 52.5 5.9 17.3 88.0 41.1 23.1 53.8 45.2 49.9 14.6 19.8 13.9 47.8 36.2 74.3 18.4 22.0 30.0 16.7 26.5 43.7 14.5 22.3 12.2 50.8 90.1 97.6 24.5 55.2 33.8 12.2 29.1 24.0 2.1 11.1 9.5 29.4 37.6 19.9 11.8 116.6 37.6 12.4 16.6 28.2 13.1 37.2 41.6 8.7 14.1 38.8 89.4 35.3 19.0 12.4 32.4 132.8 MAP10 "KIAA1383, MTR120" ENSG00000212916 "Microtubule associated protein 10" Q9P2G4 1 232804892-232808407 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.3;Cone photoreceptor cells: 22.9;Spermatocytes: 11.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 6.8;NB-4: 6.7;REH: 5.5;THP-1: 10.1;U-937: 6.9" "Low region specificity" "Detected in all" HPA052496 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA052496: AB_2681852" "unprognostic (2.70e-1)" "unprognostic (6.18e-2)" "unprognostic (4.41e-2)" "unprognostic (6.05e-2)" "unprognostic (4.41e-1)" "unprognostic (3.06e-2)" "unprognostic (1.87e-2)" "unprognostic (4.60e-1)" "unprognostic (6.84e-2)" "unprognostic (1.04e-1)" "unprognostic (6.26e-3)" "unprognostic (2.03e-2)" "unprognostic (1.73e-3)" "unprognostic (3.97e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-1)" "unprognostic (7.98e-2)" 1.0 1.0 0.5 1.2 0.7 0.7 1.8 0.2 0.8 1.6 0.0 0.9 1.4 1.1 2.6 0.5 1.3 1.3 2.6 0.6 0.6 1.1 2.5 1.2 2.7 0.7 0.2 2.2 1.7 0.7 0.8 1.1 0.6 1.0 0.8 3.6 1.5 0.9 2.6 0.4 1.7 1.3 0.2 1.5 1.5 3.1 0.2 3.7 2.2 1.5 2.0 0.9 0.5 0.5 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.8 0.6 0.2 0.3 0.0 4.0 0.0 2.0 1.6 0.0 0.0 0.0 0.9 0.6 1.5 0.0 0.2 0.2 0.0 1.7 2.6 0.0 2.4 0.2 0.2 0.0 0.3 3.1 0.0 1.0 0.0 1.4 1.9 6.8 6.7 0.0 1.7 0.0 5.5 0.0 1.9 1.4 1.6 3.3 2.7 0.0 0.3 0.0 0.9 0.6 10.1 0.7 0.0 1.7 0.2 1.2 1.9 0.0 0.0 1.5 6.9 0.1 5.1 1.9 1.7 0.5 1.4 0.6 0.6 0.8 0.2 2.5 1.3 1.2 0.9 0.0 1.2 3.2 2.9 1.4 0.7 0.5 0.7 0.2 0.8 0.6 0.6 0.7 0.2 0.6 0.2 0.2 0.5 4.4 0.0 1.1 0.7 1.6 0.4 0.3 1.0 1.2 12.3 1.0 1.0 4.9 5.7 2.1 0.0 22.9 0.7 1.9 0.7 0.0 2.9 3.1 1.0 2.2 2.6 0.0 0.4 4.2 3.0 0.5 1.8 1.5 0.5 1.3 3.4 0.4 1.3 1.5 0.0 3.5 2.3 6.1 1.2 0.8 2.2 0.6 1.1 0.0 1.0 5.6 3.2 2.1 2.5 3.2 1.7 0.3 0.7 0.7 0.2 1.9 0.2 1.5 8.5 0.0 2.4 1.2 11.2 6.1 0.8 0.3 0.3 1.3 4.4 2.0 0.4 MARCO "SCARA2, SR-A6" ENSG00000019169 "Macrophage receptor with collagenous structure" Q9UEW3 2 118942194-118994660 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 94.9;lung: 199.6;lymphoid tissue: 87.9" "Cell type enriched" "Detected in many" 6 "Kupffer cells: 1269.8" "Cancer enhanced" "Detected in many" "lung cancer: 21.6" "Group enriched" "Detected in many" 4 "cerebral cortex: 4.1;thalamus: 12.6" "Group enriched" "Detected in some" 4 "classical monocyte: 33.7;intermediate monocyte: 56.5" "Lineage enriched" "Detected in many" 5 "monocytes: 56.5" "Cell line enhanced" "Detected in some" "HaCaT: 1.7;THP-1: 2.5;U-2 OS: 2.6;U-266/70: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA063793 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 30000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus" Vesicles "HPA063793: AB_2685123" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (5.96e-3)" "unprognostic (3.36e-2)" "unprognostic (1.71e-2)" "unprognostic (3.58e-2)" "unprognostic (3.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (6.27e-3)" "unprognostic (5.13e-2)" "unprognostic (2.24e-3)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (6.55e-2)" 64.7 31.1 0.4 87.9 1.4 3.4 7.4 0.7 4.1 0.7 4.4 5.7 2.0 0.7 1.3 2.4 25.5 2.4 19.0 0.9 1.0 1.6 94.9 199.6 17.7 1.2 1.7 7.5 0.8 0.3 1.5 2.8 1.9 1.8 2.1 0.0 4.4 2.3 1.5 2.5 3.1 29.8 1.2 37.1 3.5 2.0 12.6 1.3 1.5 5.0 1.1 25.2 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.6 0.4 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 33.7 0.0 0.0 56.5 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.7 0.0 7.2 1.0 0.0 9.2 0.4 1.4 0.7 4.1 0.9 1.0 1.2 1.7 1.9 1.2 12.6 0.7 0.7 25.6 45.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 3.4 1.8 0.4 1.5 16.7 3.7 0.0 0.7 1.4 0.1 0.0 3.9 0.0 0.0 0.0 5.2 0.0 8.0 0.0 0.2 1.1 2.6 0.0 0.0 12.6 0.0 11.4 3.4 169.6 0.0 0.0 0.0 0.0 1269.8 46.4 0.1 0.0 199.3 0.0 2.8 23.2 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.5 0.1 0.0 0.2 13.1 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.9 1.9 4.1 0.0 0.0 0.1 MEFV "FMF, MEF, TRIM20" ENSG00000103313 "MEFV innate immuity regulator, pyrin" O15553 16 3242027-3256633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" Actin-binding "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.1;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 7.6;Kupffer cells: 15.1;Macrophages: 15.5;monocytes: 26.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "neutrophil: 8.3" "Group enriched" "Detected in many" 4 "granulocytes: 8.3;monocytes: 5.7" "Cell line enriched" "Detected in some" 6 "THP-1: 6.6" "Not detected" "Not detected" HPA077497 Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Cytosol "HPA077497: " "unprognostic (2.67e-1)" "unprognostic (1.06e-1)" "unprognostic (4.96e-2)" "unprognostic (2.01e-1)" "unprognostic (2.49e-2)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "unprognostic (3.35e-2)" "unprognostic (2.97e-2)" "unprognostic (1.09e-1)" "unprognostic (8.89e-2)" "unprognostic (3.27e-1)" "unprognostic (7.58e-7)" "unprognostic (1.08e-1)" "unprognostic (7.16e-4)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" 2.4 0.6 0.1 6.5 0.2 6.1 0.3 0.4 1.0 0.2 0.3 0.4 0.5 0.2 0.2 0.3 0.6 1.0 0.5 0.3 0.1 0.4 0.7 4.0 0.4 0.3 0.2 0.1 0.2 0.0 0.2 0.8 0.5 0.2 0.3 0.2 0.3 0.0 0.7 0.2 0.6 1.0 0.0 8.9 0.4 1.3 0.3 0.4 0.3 0.3 0.3 1.8 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.2 1.1 0.0 2.4 3.2 0.1 0.0 3.4 0.0 0.1 0.1 0.0 1.7 0.2 0.0 0.1 8.3 0.3 5.7 0.1 0.0 1.2 0.1 0.2 0.4 1.0 0.3 0.1 0.3 0.2 0.5 0.0 0.3 0.4 0.2 0.0 1.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.3 7.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.4 0.2 1.0 0.0 0.1 0.0 0.0 15.1 2.4 0.3 0.0 15.5 0.0 0.0 26.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.0 0.5 0.2 0.3 0.7 0.0 0.1 0.0 0.6 0.0 0.0 0.1 METTL14 KIAA1627 ENSG00000145388 "Methyltransferase like 14" Q9HCE5 4 118685392-118715433 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038002 Supported Supported Nucleoplasm Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA038002: AB_10672401" "unprognostic (4.48e-1)" "unprognostic (5.13e-2)" "unprognostic (5.98e-3)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.83e-1)" "unprognostic (3.75e-2)" "unprognostic (4.40e-1)" "unprognostic (9.97e-2)" "unprognostic (2.40e-2)" "unprognostic (3.64e-2)" "unprognostic (3.33e-3)" "prognostic favorable (1.46e-5)" "unprognostic (1.05e-1)" "unprognostic (1.32e-1)" "unprognostic (1.76e-3)" "unprognostic (7.76e-3)" 8.9 8.8 5.2 8.6 6.0 19.5 11.5 6.8 6.3 8.8 5.5 8.8 8.8 11.7 10.7 8.9 8.8 7.7 8.3 4.8 6.3 10.2 14.9 9.1 11.6 5.5 5.2 12.7 7.8 10.9 8.2 9.0 6.3 9.7 8.2 11.7 7.6 8.0 8.4 10.9 9.2 9.2 5.4 10.8 7.9 15.1 5.7 12.5 10.6 7.7 11.0 8.5 7.9 7.4 19.6 8.9 19.0 17.8 11.7 14.7 13.8 17.1 13.0 12.6 14.4 12.9 22.8 22.0 9.8 12.0 12.6 9.4 16.2 14.1 16.1 17.5 9.8 18.5 11.4 14.4 13.3 30.2 21.2 13.1 15.8 14.6 9.6 16.5 11.5 17.4 20.1 18.2 17.5 13.2 29.7 24.7 16.2 16.7 7.7 16.8 23.7 11.2 13.8 12.7 15.4 17.3 12.0 22.0 17.2 17.2 10.0 28.5 15.8 18.1 16.6 16.3 13.7 15.2 17.0 24.9 12.9 16.5 15.1 37.7 12.8 29.0 17.0 19.6 19.3 24.3 17.8 17.7 15.3 25.3 21.0 19.0 10.3 21.8 23.7 12.1 20.8 13.7 5.2 6.0 6.8 6.3 4.8 6.3 5.5 5.2 6.3 5.4 5.7 7.4 18.6 25.6 25.9 14.7 20.6 10.8 18.3 10.6 16.5 16.8 13.4 12.6 15.7 17.2 20.8 23.9 22.9 18.7 28.3 13.7 11.7 11.9 96.9 14.5 21.7 17.3 12.1 8.4 18.7 15.6 10.2 16.8 9.2 18.0 22.1 18.3 16.4 32.1 12.1 8.4 17.0 15.2 6.1 17.9 7.6 16.7 18.6 13.3 7.2 14.0 14.0 13.4 25.7 14.1 26.9 14.8 13.0 13.9 8.2 17.1 15.4 20.6 15.2 25.4 13.1 15.3 15.5 42.2 28.1 12.4 11.9 15.3 20.6 17.0 12.8 16.0 MFSD2A "FLJ14490, MFSD2" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 96.9;liver: 162.0;skin 1: 87.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 136.2;Hepatocytes: 299.6;Proximal enterocytes: 235.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 12 "dendritic cells: 24.3;monocytes: 13.2" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 52.0;THP-1: 169.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Plasma membrane, Cytoplasmic bodies" "HPA043107: AB_10794387" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (6.92e-2)" "unprognostic (2.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (9.26e-2)" "unprognostic (4.11e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.33e-4)" 6.3 1.4 34.0 3.4 31.7 8.4 13.4 34.8 36.0 4.8 22.2 7.2 14.6 8.5 96.9 12.5 3.5 2.3 1.4 30.9 33.4 5.8 162.0 36.1 2.3 38.5 33.8 2.2 0.6 0.7 8.0 17.1 38.6 2.4 5.0 2.6 4.0 79.2 0.5 87.8 32.0 3.5 32.8 1.5 1.9 33.9 37.2 1.6 7.5 0.1 3.6 20.2 14.1 33.1 6.2 2.7 12.5 18.9 8.7 1.6 0.0 5.9 11.2 12.8 15.1 0.8 3.4 38.0 3.4 3.0 8.8 15.0 12.4 21.8 9.8 4.9 6.0 4.6 0.1 0.1 28.8 6.8 21.8 9.7 13.3 52.0 21.5 2.3 3.1 11.5 0.0 9.5 5.7 0.8 10.6 10.4 10.1 21.4 4.7 7.4 18.5 8.7 2.1 17.9 4.4 6.7 4.5 31.7 3.0 1.1 1.5 169.8 2.0 2.7 5.3 9.5 24.9 1.8 3.5 8.5 28.9 26.0 9.2 0.0 13.2 1.4 0.1 6.6 0.2 1.5 0.1 0.2 14.7 0.2 0.0 0.1 0.7 0.2 1.2 24.3 0.0 3.6 34.0 31.7 34.8 36.0 30.9 33.4 38.5 33.8 38.6 32.8 37.2 33.1 0.5 19.2 136.2 3.3 6.3 52.8 21.2 40.0 51.2 2.0 6.3 2.3 0.6 12.8 30.8 16.5 0.0 0.5 5.7 62.2 0.0 3.4 1.0 25.8 5.5 22.9 1.2 5.7 1.5 24.8 7.6 9.7 24.5 61.8 17.2 0.1 7.1 299.6 6.7 0.0 1.3 34.5 12.2 9.8 43.3 2.7 0.6 16.1 0.0 38.4 5.5 38.8 0.0 0.0 1.6 27.2 39.3 0.4 5.0 13.9 235.1 6.1 33.9 2.7 0.0 5.0 3.3 1.0 1.3 49.3 54.8 52.5 3.3 0.1 20.7 26.6 MICAL1 "DKFZp434B1517, FLJ11937, FLJ21739, MICAL, NICAL" ENSG00000135596 "Microtubule associated monooxygenase, calponin and LIM domain containing 1" Q8TDZ2 6 109444062-109465968 "Enzymes, Predicted intracellular proteins" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 76.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 148.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA030175, HPA030176, HPA030178" Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "HPA030175: AB_2673359, HPA030176: AB_2673360, HPA030178: AB_10600824" "unprognostic (1.07e-2)" "unprognostic (1.86e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-1)" "unprognostic (2.21e-1)" "unprognostic (2.71e-3)" "unprognostic (1.52e-2)" "unprognostic (1.92e-2)" "unprognostic (6.93e-2)" "unprognostic (1.94e-1)" "prognostic favorable (2.63e-7)" "unprognostic (2.31e-1)" "prognostic unfavorable (6.71e-7)" "unprognostic (2.05e-1)" "unprognostic (3.27e-1)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" 20.6 6.3 17.8 27.6 17.5 65.9 14.2 17.8 25.6 48.6 16.1 21.7 37.8 29.6 2.5 11.8 32.7 14.7 11.1 17.8 19.9 18.8 5.4 35.2 32.8 20.7 18.4 13.6 8.7 9.2 17.9 10.7 20.6 30.8 10.1 6.2 11.0 18.8 5.1 16.0 43.2 9.1 18.1 56.7 18.3 18.7 20.3 18.3 12.6 3.9 16.6 62.2 30.8 22.4 4.1 5.1 15.8 0.2 55.9 43.6 10.7 31.3 22.0 6.7 11.0 7.3 4.7 23.2 6.6 33.1 19.4 5.4 9.6 12.3 2.8 20.3 4.0 9.9 12.0 11.5 22.8 6.5 0.3 25.7 6.2 15.5 12.6 25.2 20.0 14.0 2.7 40.2 40.6 5.1 8.0 36.0 9.9 5.5 5.4 21.9 10.0 3.3 15.0 10.0 5.3 28.1 2.9 2.7 50.4 10.0 4.9 148.8 21.6 16.7 5.9 9.8 12.2 29.7 9.6 20.8 13.9 21.4 12.3 14.6 7.3 13.6 6.5 13.2 3.9 3.5 6.4 5.2 12.8 5.1 4.3 3.1 9.3 5.1 14.2 14.4 9.4 6.8 17.8 17.5 17.8 25.6 17.8 19.9 20.7 18.4 20.6 18.1 20.3 22.4 5.3 44.8 14.4 3.3 26.2 6.1 1.3 2.3 1.2 3.4 2.5 3.6 4.4 0.0 4.2 1.8 4.2 1.3 31.0 24.9 1.9 7.8 13.2 2.0 29.8 5.9 32.2 4.6 13.8 6.5 10.9 9.7 76.9 2.4 15.2 3.1 4.6 0.3 32.2 0.0 12.9 34.9 6.1 28.3 44.5 23.1 20.8 34.7 16.0 8.4 34.0 2.2 21.6 12.5 4.2 11.6 27.6 37.6 15.4 1.3 49.6 4.6 10.7 18.3 0.0 31.6 27.3 7.9 9.5 0.7 4.8 4.8 22.5 2.9 13.9 1.5 MLC1 "KIAA0027, LVM, MLC, VL" ENSG00000100427 "Modulator of VRAC current 1" Q15049 22 50059391-50085426 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 262.7;choroid plexus: 145.6" "Cell type enriched" "Detected in some" 6 "Astrocytes: 115.6" "Cancer enriched" "Detected in some" 69 "glioma: 122.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 20.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HL-60: 228.2;NB-4: 219.8;THP-1: 401.5;U-266/70: 131.6;U-266/84: 120.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003040 Enhanced Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA003040: AB_1079387" "unprognostic (2.68e-2)" "unprognostic (5.46e-6)" "unprognostic (5.41e-3)" "unprognostic (1.51e-1)" "unprognostic (1.47e-1)" "unprognostic (2.42e-3)" "unprognostic (9.54e-3)" "unprognostic (7.21e-2)" "unprognostic (2.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.31e-1)" "unprognostic (1.51e-3)" "unprognostic (8.39e-4)" "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (3.66e-2)" "unprognostic (2.92e-1)" 0.3 0.1 239.3 0.7 235.7 36.4 0.1 212.7 261.8 3.0 145.6 0.1 0.4 0.3 1.0 0.1 1.8 1.0 0.6 225.8 234.5 0.1 0.4 1.6 0.3 262.7 243.1 0.3 0.1 0.0 1.1 2.3 221.8 4.8 0.0 4.1 0.1 1.4 0.1 1.0 0.1 0.2 231.9 2.2 0.2 3.8 231.5 0.5 0.1 0.0 0.5 0.4 11.9 217.2 0.4 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 68.1 0.0 0.0 0.1 228.2 68.4 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 1.8 219.8 0.3 0.0 0.1 24.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 401.5 0.0 0.0 0.2 0.1 0.3 131.6 120.2 0.4 0.3 35.7 2.2 0.0 1.1 0.0 3.9 6.8 0.1 0.1 0.3 1.6 0.9 0.0 0.1 1.8 0.1 20.2 9.2 0.2 0.1 4.0 239.3 235.7 212.7 261.8 225.8 234.5 262.7 243.1 221.8 231.9 231.5 217.2 0.0 0.0 0.5 115.6 0.3 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.1 17.2 0.0 0.0 0.0 1.1 0.1 0.4 0.1 0.0 7.8 0.4 0.0 0.1 2.4 0.0 0.1 1.3 4.4 0.4 0.0 3.5 0.0 0.5 0.0 0.0 0.3 0.0 0.7 0.0 0.6 1.8 7.5 0.6 16.3 18.6 0.5 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.3 2.7 0.1 0.0 0.0 MLNR GPR38 ENSG00000102539 "Motilin receptor" O43193 13 49220338-49222377 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.3;thyroid gland: 1.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "testis cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.3;THP-1: 4.0" "Not detected" "Not detected" HPA070324 Approved "Plasma membrane,Cytosol" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Plasma membrane, Cytosol" "HPA070324: " "unprognostic (9.75e-2)" "unprognostic (2.13e-2)" "unprognostic (2.90e-1)" "unprognostic (1.13e-1)" "unprognostic (6.03e-2)" "unprognostic (7.80e-2)" "unprognostic (1.54e-2)" "unprognostic (7.79e-2)" "unprognostic (1.88e-2)" "unprognostic (3.74e-1)" "unprognostic (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.38e-1)" 0.0 0.0 0.1 0.0 0.3 1.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.4 0.1 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.3 0.3 0.4 0.3 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MNDA PYHIN3 ENSG00000163563 "Myeloid cell nuclear differentiation antigen" P41218 1 158831351-158849506 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 292.9;lymphoid tissue: 107.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 219.1;Kupffer cells: 408.5;Langerhans cells: 241.7;Macrophages: 412.0;monocytes: 1118.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 6012.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 6012.8" "Group enriched" "Detected in some" 14 "NB-4: 151.8;THP-1: 282.7;U-937: 185.5" "Low region specificity" "Detected in all" "HPA034532, HPA073215" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles,Cytosol" NA NA 400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Nucleoli, Nucleoli rim, Vesicles, Cytosol" "HPA034532: AB_10669677, HPA073215: AB_2686582" "unprognostic (1.53e-2)" "unprognostic (7.84e-3)" "unprognostic (2.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.42e-1)" "unprognostic (1.41e-2)" "unprognostic (2.02e-2)" "unprognostic (7.99e-3)" "unprognostic (1.58e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (9.89e-2)" "unprognostic (1.96e-2)" "unprognostic (1.07e-1)" "unprognostic (4.95e-2)" "unprognostic (2.81e-2)" "unprognostic (1.02e-1)" 24.2 14.9 2.7 82.4 2.8 292.9 6.0 2.9 4.4 6.3 3.2 6.7 3.7 4.0 1.4 7.4 5.7 26.6 4.3 2.6 3.1 3.6 11.5 47.3 15.6 5.2 4.3 2.2 4.8 3.7 1.6 20.4 4.3 3.8 7.7 12.1 5.7 3.5 3.8 5.1 7.7 20.7 5.1 107.8 4.5 5.1 4.2 14.4 3.8 19.0 14.5 23.4 1.8 5.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 14.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 282.7 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.0 185.5 0.0 155.4 1354.4 243.8 2.6 534.3 3.7 33.5 1.6 1.9 616.5 15.3 1.6 1.4 6012.8 2.8 270.6 9.6 1.5 1099.5 2.7 2.8 2.9 4.4 2.6 3.1 5.2 4.3 4.3 5.1 4.2 5.4 2.6 35.3 56.0 0.0 34.7 2.4 0.0 0.0 0.0 1.2 1.1 3.4 0.9 5.7 9.3 0.0 0.0 0.9 5.9 0.0 0.0 0.0 0.4 0.1 0.1 5.0 0.0 22.3 0.0 0.4 1.3 6.5 0.5 0.1 44.1 0.0 3.9 2.2 219.1 0.0 0.1 0.0 0.0 408.5 241.7 3.3 1.2 412.0 1.8 33.7 1118.9 136.1 26.8 0.5 0.1 0.0 0.0 0.0 1.1 0.0 0.0 1.7 8.0 4.8 13.1 1.5 8.2 0.9 0.3 0.4 2.3 1.0 11.7 0.0 0.0 0.1 MRPL18 HSPC071 ENSG00000112110 "Mitochondrial ribosomal protein L18" Q9H0U6 6 159789812-159798436 "Predicted intracellular proteins, Ribosomal proteins" Transport "Chaperone, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028774, HPA028775" Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" "HPA028774: AB_10600113, HPA028775: AB_10601440" "unprognostic (4.73e-3)" "unprognostic (9.67e-2)" "unprognostic (5.90e-2)" "unprognostic (1.79e-1)" "unprognostic (1.07e-1)" "unprognostic (3.34e-3)" "prognostic unfavorable (3.61e-4)" "unprognostic (3.44e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-1)" "unprognostic (3.56e-1)" "unprognostic (7.91e-2)" "prognostic unfavorable (9.02e-5)" "unprognostic (3.51e-1)" "unprognostic (7.14e-2)" "unprognostic (1.35e-2)" "unprognostic (5.22e-2)" 45.1 55.8 75.0 42.0 77.6 45.8 39.0 78.6 122.5 41.1 76.3 55.6 43.0 45.8 51.3 52.0 53.7 35.9 64.6 76.1 77.4 55.1 65.2 36.8 54.8 76.6 75.0 42.9 40.6 43.6 38.4 41.2 76.8 42.4 46.5 28.1 44.5 43.9 77.4 40.9 38.8 48.7 77.4 35.0 45.0 30.2 77.0 50.3 34.9 74.1 48.6 50.1 42.8 82.3 77.5 148.5 55.1 140.1 78.4 86.7 109.7 105.6 89.7 124.1 128.8 172.4 68.5 118.1 88.5 88.8 185.9 107.4 205.1 129.9 118.4 81.4 166.7 117.9 119.8 303.1 87.6 117.6 100.4 67.9 113.0 132.5 97.1 80.0 110.3 121.4 172.4 120.2 115.1 119.5 155.4 256.2 77.2 149.2 143.6 106.6 54.6 196.1 140.3 49.6 92.2 59.1 102.6 165.9 65.7 56.0 102.3 283.7 70.5 93.8 106.0 159.8 212.8 98.5 196.7 139.8 142.7 245.1 116.6 130.6 116.3 108.9 92.6 152.9 107.6 154.3 118.2 103.9 134.4 132.2 131.4 117.6 23.2 110.8 175.9 167.9 137.5 193.0 75.0 77.6 78.6 122.5 76.1 77.4 76.6 75.0 76.8 77.4 77.0 82.3 93.8 51.3 30.5 9.1 62.2 127.3 271.8 170.1 63.2 29.8 98.3 127.6 61.4 108.7 98.6 53.3 16.7 103.8 66.1 94.9 211.3 125.4 226.8 95.9 74.2 73.6 143.5 49.2 11.8 110.9 194.2 77.5 44.9 74.0 93.4 56.0 41.4 86.7 126.8 23.5 12.7 131.5 124.1 48.9 170.4 58.8 90.4 106.1 106.7 11.2 81.7 92.1 75.2 8.5 15.6 126.7 116.2 83.1 54.5 210.4 75.6 192.5 120.4 42.4 85.5 51.1 106.3 258.2 125.8 72.8 119.2 74.8 90.1 108.9 138.7 172.6 MS4A14 "DKFZp434H092, FLJ32856, MS4A16, NYD-SP21" ENSG00000166928 "Membrane spanning 4-domains A14" Q96JA4 11 60378530-60417756 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 73.0" "Group enriched" "Detected in some" 44 "Early spermatids: 262.3;Late spermatids: 672.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.5;non-classical monocyte: 8.0" "Lineage enriched" "Detected in many" 5 "monocytes: 8.0" "Cell line enriched" "Detected in single" 23 "THP-1: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA058973 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA058973: " "unprognostic (1.78e-1)" "unprognostic (1.76e-1)" "unprognostic (5.75e-2)" "unprognostic (1.77e-1)" "unprognostic (1.27e-1)" "unprognostic (1.79e-2)" "unprognostic (1.24e-1)" "unprognostic (3.45e-2)" "unprognostic (4.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.77e-1)" "unprognostic (2.14e-1)" "unprognostic (4.50e-6)" "unprognostic (3.73e-2)" "unprognostic (7.16e-3)" "unprognostic (8.40e-2)" "unprognostic (7.11e-2)" 5.1 3.7 6.2 3.5 5.6 0.6 3.6 5.8 8.8 1.2 7.5 2.7 0.7 0.9 0.6 0.9 1.3 0.9 2.6 5.8 6.3 1.8 2.0 11.9 1.3 7.7 6.8 0.7 1.3 0.3 1.5 2.4 7.2 1.8 1.1 0.4 1.9 0.5 0.9 0.9 2.7 1.2 6.0 10.4 1.2 73.0 8.5 0.3 1.5 0.3 1.9 2.0 1.2 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 3.4 0.0 0.0 5.5 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.9 6.2 5.6 5.8 8.8 5.8 6.3 7.7 6.8 7.2 6.0 8.5 8.0 0.2 0.0 1.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 262.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 7.3 5.5 672.0 4.1 10.4 0.0 3.7 5.7 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.7 0.0 6.6 0.1 0.0 6.5 3.4 0.0 0.3 0.1 0.1 0.0 0.0 0.0 MS4A3 "CD20L, HTM4" ENSG00000149516 "Membrane spanning 4-domains A3" Q96HJ5 11 60056587-60071115 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 93 "bone marrow: 420.2" "Cell type enriched" "Detected in some" 5 "Erythroid cells: 19.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 1478 "basophil: 2686.3" "Lineage enriched" "Detected in single" 4507 "granulocytes: 2686.3" "Cell line enhanced" "Detected in some" "HEL: 48.9;K-562: 94.2;NB-4: 109.8;THP-1: 319.0;U-937: 126.2" "Not detected" "Not detected" HPA019210 Supported Approved "Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA019210: AB_1854134" "unprognostic (6.37e-3)" "unprognostic (1.25e-1)" "unprognostic (2.67e-1)" "unprognostic (3.77e-1)" 0.1 0.0 0.0 0.3 0.0 420.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 4.5 0.0 0.5 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 48.9 0.0 0.0 0.0 17.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.2 0.0 0.0 0.0 0.0 109.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 319.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 126.2 0.0 2686.3 0.1 1.8 0.1 0.1 0.3 0.2 0.4 0.0 0.3 0.2 0.2 0.4 0.9 0.1 0.5 0.2 0.1 8.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 19.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.3 0.0 0.0 0.8 0.0 3.6 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 580.8;Hofbauer cells: 376.8;Kupffer cells: 1649.6;Langerhans cells: 470.0;Macrophages: 675.9;monocytes: 429.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cell line enriched" "Detected in some" 8 "THP-1: 47.9" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" 72.6 42.3 10.7 57.5 10.9 33.5 40.0 10.8 22.5 28.1 14.7 41.0 27.8 14.3 9.6 25.7 16.8 61.4 22.8 10.0 11.8 11.5 108.6 56.4 109.1 15.8 13.7 12.3 7.8 8.7 9.8 65.2 14.8 12.4 54.9 1.4 16.0 18.3 5.3 7.3 45.1 52.6 12.4 121.5 24.5 7.8 13.6 32.2 10.0 17.7 47.6 59.9 8.6 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.1 0.0 406.4 1095.3 8.2 1.6 345.6 3.4 9.6 2.2 1.4 638.8 1.5 1.0 1.0 72.8 2.1 24.4 454.4 1.9 752.8 10.7 10.9 10.8 22.5 10.0 11.8 15.8 13.7 14.8 12.4 13.6 17.6 5.3 6.4 22.9 0.0 16.1 9.3 0.6 0.0 1.2 0.3 2.2 8.0 3.3 17.2 2.5 3.7 0.0 2.0 220.6 0.3 0.0 0.0 2.2 0.4 0.2 12.8 0.0 43.9 0.1 0.0 2.7 4.3 2.6 0.2 13.9 0.1 580.8 20.5 376.8 0.0 0.1 0.1 0.0 1649.6 470.0 5.1 1.5 675.9 14.2 40.3 429.2 0.0 11.3 0.5 0.1 0.0 1.2 0.0 2.0 0.2 0.0 0.5 1.5 0.6 46.0 3.0 4.4 0.5 1.1 2.4 8.0 2.1 10.4 0.1 0.2 0.3 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 MTM1 ENSG00000171100 "Myotubularin 1" Q13496 X 150568621-150673143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 52.2;Oligodendrocytes: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010008, HPA010665" Approved Supported "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA010008: AB_1079426, HPA010665: AB_1079425" "unprognostic (3.66e-3)" "unprognostic (8.43e-3)" "unprognostic (3.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.08e-1)" "unprognostic (6.45e-2)" "unprognostic (4.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.74e-1)" "unprognostic (2.35e-2)" "unprognostic (1.08e-1)" "unprognostic (4.59e-2)" "prognostic favorable (7.40e-7)" "unprognostic (4.46e-2)" "unprognostic (1.25e-1)" "unprognostic (4.99e-2)" "unprognostic (2.46e-1)" 6.8 11.1 7.4 9.7 8.3 11.3 7.6 8.0 8.4 5.7 6.1 19.8 11.7 6.5 8.4 7.5 9.6 7.1 7.3 6.9 8.5 12.9 18.4 11.2 12.4 7.8 8.6 11.7 4.9 16.0 3.8 6.3 8.0 8.0 19.2 5.4 6.3 10.7 11.8 8.2 12.1 6.9 7.7 11.9 7.8 11.5 8.8 8.4 11.2 10.1 9.7 7.1 4.7 8.8 14.3 6.1 8.5 3.1 7.5 7.3 5.4 6.1 8.5 7.0 7.9 4.7 7.3 22.2 11.4 8.3 21.9 9.9 6.1 11.5 8.6 6.4 5.2 5.6 5.4 15.0 5.8 25.2 19.1 4.5 14.3 5.7 11.9 6.9 9.4 9.3 3.9 19.8 8.8 4.5 6.9 25.2 4.3 13.4 7.4 8.0 4.9 4.5 11.7 6.9 2.2 2.4 5.5 11.3 8.5 11.9 4.1 35.2 8.2 5.0 3.1 12.4 7.1 4.2 10.0 20.3 6.0 14.8 8.0 34.8 9.5 27.9 2.0 10.8 6.8 8.0 9.6 7.3 12.0 10.6 9.0 5.4 11.6 14.6 9.8 7.4 12.2 7.1 7.4 8.3 8.0 8.4 6.9 8.5 7.8 8.6 8.0 7.7 8.8 8.8 9.9 9.6 20.0 52.2 13.9 15.2 8.3 5.8 2.2 0.0 5.8 3.9 15.0 4.3 6.0 3.7 0.0 2.1 8.4 33.0 1.9 3.4 35.6 7.7 5.0 11.5 9.6 7.4 44.0 4.3 2.8 6.6 8.2 4.8 8.8 3.3 16.4 13.2 8.0 0.0 41.5 17.7 2.0 16.3 10.4 18.8 6.2 13.0 5.4 24.4 12.0 0.0 0.0 27.6 47.7 4.7 9.5 12.8 8.0 6.8 11.2 14.7 13.4 0.0 0.0 5.2 6.9 5.1 4.1 4.9 19.0 7.3 12.8 4.8 13.8 9.7 NAAA ASAHL ENSG00000138744 "N-acylethanolamine acid amidase" Q02083 4 75913660-75941013 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 142.2;Kupffer cells: 115.8;Langerhans cells: 109.9;Proximal enterocytes: 167.7" "Cancer enriched" "Detected in all" 4 "prostate cancer: 31.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 672.4;non-classical monocyte: 583.3" "Lineage enriched" "Detected in all" 5 "monocytes: 672.4" "Cell line enhanced" "Detected in many" "U-2197: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026135 Approved "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "CAB026135: " "unprognostic (5.30e-3)" "unprognostic (1.23e-2)" "unprognostic (1.41e-2)" "prognostic favorable (1.93e-4)" "unprognostic (1.10e-1)" "unprognostic (2.17e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-2)" "unprognostic (2.24e-1)" "unprognostic (2.87e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.63e-1)" "unprognostic (2.15e-2)" "unprognostic (2.54e-1)" "unprognostic (3.20e-2)" "unprognostic (3.42e-3)" "unprognostic (6.21e-2)" 19.0 14.6 9.2 30.0 10.0 18.5 37.4 10.9 10.8 23.0 14.1 61.8 30.9 12.9 9.1 28.4 16.4 15.7 19.9 9.5 13.3 40.6 68.4 23.0 48.4 11.2 11.1 8.2 7.6 11.7 7.7 19.4 11.7 70.9 69.9 32.7 31.5 11.4 8.6 22.8 60.7 15.4 9.5 63.8 18.5 3.4 13.2 16.3 15.9 13.0 27.9 20.0 18.4 14.5 11.9 26.6 1.1 0.7 62.4 62.8 1.1 17.5 11.6 11.8 4.0 9.3 41.1 1.0 8.9 43.5 0.4 23.1 34.8 13.4 7.1 17.0 1.3 8.4 19.4 22.6 14.3 31.4 29.6 16.0 10.0 10.3 3.5 18.4 19.1 18.7 9.6 35.9 10.6 43.5 20.2 20.5 13.5 53.4 10.5 13.5 0.4 55.6 12.4 6.7 15.9 2.3 18.1 56.2 5.4 1.8 63.3 54.1 28.8 0.7 1.5 78.6 0.8 8.8 3.8 5.9 14.8 44.5 7.4 48.6 270.1 110.3 62.0 672.4 67.5 58.8 78.4 61.8 143.2 40.4 65.2 54.5 90.3 35.5 583.3 53.2 114.6 233.7 9.2 10.0 10.9 10.8 9.5 13.3 11.2 11.1 11.7 9.5 13.2 14.5 10.6 0.0 7.3 7.2 31.2 11.3 18.8 5.7 4.0 11.5 31.3 14.2 4.4 25.8 10.9 5.5 18.8 24.6 19.5 142.2 13.7 5.7 0.5 12.1 18.1 14.6 48.0 10.8 17.7 8.4 19.2 28.2 3.1 11.9 15.2 3.5 18.5 37.2 39.7 11.8 27.4 45.4 8.2 115.8 109.9 0.0 10.5 80.3 17.8 7.5 77.8 7.7 16.5 5.0 4.8 4.1 46.7 7.5 16.8 55.4 167.7 12.4 27.7 86.9 0.0 31.8 16.7 1.1 0.9 15.9 18.9 13.3 34.8 9.1 24.4 14.0 NCKAP1L HEM1 ENSG00000123338 "NCK associated protein 1 like" P55160 12 54497752-54548243 "Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.9" "Cell type enhanced" "Detected in many" "B-cells: 66.2;dendritic cells: 92.3;Hofbauer cells: 115.5;Kupffer cells: 175.1;Macrophages: 108.1;monocytes: 153.2;NK-cells: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 112.4;HMC-1: 112.4;NB-4: 82.6;REH: 59.1;THP-1: 121.3;U-937: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039490, HPA040772" Approved Uncertain "Plasma membrane,Cytosol" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "Plasma membrane" "HPA039490: AB_2676540, HPA040772: AB_2677129" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (1.61e-2)" "unprognostic (1.22e-3)" "unprognostic (9.29e-2)" "unprognostic (1.01e-2)" "unprognostic (3.69e-1)" "unprognostic (2.95e-2)" "unprognostic (6.53e-3)" "unprognostic (4.80e-1)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (1.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.76e-2)" "unprognostic (3.63e-2)" "unprognostic (4.74e-2)" 9.7 4.6 3.3 34.8 4.0 28.4 4.7 3.6 3.7 4.0 4.0 19.7 5.8 2.5 1.3 6.1 3.4 7.3 2.6 2.9 3.7 2.3 7.1 20.2 42.5 6.9 4.8 1.8 1.6 4.0 1.5 11.0 6.5 4.7 9.7 0.4 3.5 5.2 1.2 2.3 18.1 10.3 5.4 44.9 6.7 1.2 6.8 37.4 2.2 2.0 43.4 27.9 2.8 8.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 47.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.3 47.9 0.0 0.0 0.0 112.4 112.4 0.0 0.0 0.0 0.0 0.0 0.7 40.1 7.7 43.7 0.0 0.0 47.9 82.6 0.1 0.0 0.0 59.1 0.2 47.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 121.3 0.0 0.2 0.0 0.1 0.1 2.4 2.9 38.4 0.2 70.4 0.0 31.7 68.6 55.0 31.7 103.9 26.2 30.2 28.3 32.7 72.0 28.8 17.9 26.4 16.9 36.1 121.3 40.8 45.1 65.1 3.3 4.0 3.6 3.7 2.9 3.7 6.9 4.8 6.5 5.4 6.8 8.4 1.0 0.0 11.6 0.3 66.2 1.3 0.3 0.0 0.0 1.3 0.6 2.2 1.5 4.3 1.8 0.0 0.0 0.7 92.3 0.2 0.0 0.1 0.9 0.2 0.3 3.6 0.0 22.1 0.8 0.4 1.0 2.7 2.0 0.3 56.3 0.1 7.5 1.4 115.5 0.0 0.5 0.0 0.0 175.1 28.5 2.3 1.2 108.1 5.4 42.2 153.2 0.4 113.3 0.5 0.0 0.0 0.1 0.0 40.0 0.1 0.0 0.3 0.7 0.9 0.0 0.8 1.3 0.9 1.6 0.1 0.6 1.4 59.7 0.2 0.0 0.2 NDUFAF1 "CGI-65, CIA30" ENSG00000137806 "NADH:ubiquinone oxidoreductase complex assembly factor 1" Q9Y375 15 41387218-41409403 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 85.3;Spermatocytes: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039933, HPA040064" Supported Approved Mitochondria,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Mitochondria, Cytosol" "HPA039933: AB_10795265, HPA040064: AB_10795687" "unprognostic (2.02e-1)" "unprognostic (1.02e-1)" "unprognostic (1.72e-1)" "unprognostic (2.10e-3)" "unprognostic (2.38e-1)" "unprognostic (1.20e-1)" "prognostic favorable (2.88e-5)" "unprognostic (3.01e-1)" "unprognostic (2.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" "prognostic favorable (3.34e-6)" "unprognostic (1.68e-1)" "unprognostic (3.23e-1)" "unprognostic (3.17e-2)" "unprognostic (2.05e-1)" 16.0 33.4 20.0 9.5 20.7 4.2 12.4 21.6 29.6 9.7 22.8 12.7 12.6 10.5 15.5 13.8 9.8 7.7 42.7 20.7 21.4 29.0 38.7 9.3 11.5 21.1 21.0 9.7 11.8 18.3 11.5 8.0 21.3 10.1 10.4 12.4 12.2 13.2 63.5 9.7 10.9 10.8 21.5 11.9 14.1 21.1 20.8 10.9 10.5 60.9 13.1 12.8 9.9 22.9 15.9 13.3 16.4 13.3 30.0 28.3 14.9 26.1 25.1 23.6 21.3 22.5 8.1 16.7 38.2 24.9 17.5 25.0 20.1 15.9 19.3 32.9 23.9 22.4 25.0 13.8 27.1 24.7 17.0 30.0 18.5 20.8 18.0 19.9 19.0 31.9 38.2 17.2 30.6 17.5 19.9 28.6 12.6 27.5 17.9 15.0 17.4 40.6 41.9 27.8 17.5 13.8 13.2 31.8 12.6 16.9 25.1 50.2 15.4 18.0 10.1 30.5 24.2 15.8 34.7 28.0 24.0 43.5 19.3 35.0 12.8 16.2 7.8 15.0 9.1 13.8 9.6 9.5 11.8 11.8 10.6 8.6 9.4 13.4 13.3 18.2 16.8 8.5 20.0 20.7 21.6 29.6 20.7 21.4 21.1 21.0 21.3 21.5 20.8 22.9 7.7 12.8 10.1 6.5 14.6 4.7 15.8 43.8 9.6 15.7 12.3 11.9 58.7 15.7 27.3 22.0 12.5 36.3 19.8 8.5 64.6 30.5 59.5 14.2 14.2 11.1 6.7 13.5 8.8 31.3 34.6 12.5 12.2 13.1 7.0 16.3 8.6 28.2 28.8 6.7 9.1 8.5 30.5 12.8 7.0 15.0 16.4 16.2 10.6 3.7 23.4 20.7 16.5 4.0 10.3 20.9 3.7 16.1 15.0 11.8 23.3 85.3 30.6 19.2 26.3 15.3 17.3 84.7 21.6 11.3 7.7 50.3 12.3 32.6 11.9 16.3 NDUFS2 CI-49 ENSG00000158864 "NADH:ubiquinone oxidoreductase core subunit S2" O75306 1 161197104-161214723 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 464.8;tongue: 633.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055140, HPA061953" Enhanced Supported Mitochondria NA NA 25000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA055140: AB_2682713, HPA061953: AB_2684646" "unprognostic (2.13e-2)" "unprognostic (2.24e-2)" "unprognostic (8.47e-2)" "unprognostic (7.78e-2)" "unprognostic (9.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-2)" "unprognostic (1.51e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-2)" "unprognostic (3.17e-2)" "unprognostic (1.11e-1)" "prognostic favorable (2.32e-4)" "unprognostic (2.35e-1)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (1.82e-1)" 60.2 98.2 38.7 37.4 41.6 39.5 49.6 46.4 48.8 40.2 76.6 96.5 102.4 41.4 33.4 62.0 52.5 36.8 273.7 40.5 47.5 137.0 177.4 48.5 42.4 49.5 40.7 51.6 47.7 156.5 35.8 41.6 53.1 45.7 101.8 36.2 53.5 49.0 464.8 51.4 81.5 58.6 41.6 43.6 73.3 29.5 47.9 48.3 45.0 633.7 60.1 57.5 40.0 49.2 101.8 129.4 95.2 104.0 115.1 102.8 77.0 85.7 105.8 139.6 107.5 143.9 98.5 108.4 168.1 113.0 81.3 135.9 129.1 131.8 122.1 84.2 108.0 105.9 109.5 136.5 117.7 116.0 105.3 147.2 112.3 121.1 137.2 96.8 160.5 115.4 139.9 72.7 132.5 93.5 81.7 58.4 175.3 288.5 116.5 72.0 83.3 172.0 157.8 109.4 97.2 152.0 93.0 237.0 151.5 116.4 221.7 342.2 108.6 84.5 66.3 65.5 123.7 125.2 172.0 95.1 123.6 109.3 105.4 150.0 159.3 85.7 82.0 193.2 82.6 81.4 86.6 86.3 217.8 68.4 86.6 88.1 86.7 93.5 190.7 128.7 130.8 167.5 38.7 41.6 46.4 48.8 40.5 47.5 49.5 40.7 53.1 41.6 47.9 49.2 70.5 35.3 45.7 30.7 47.1 38.9 52.4 277.8 52.9 74.6 58.9 50.7 232.6 74.4 148.4 77.3 31.3 146.8 47.6 187.5 332.6 184.3 11.3 43.5 57.0 67.5 72.0 78.9 28.0 143.2 111.3 69.7 80.5 41.3 69.7 99.7 65.7 206.5 150.5 92.5 30.1 122.6 242.1 87.8 42.0 7.8 43.5 66.5 83.6 14.0 97.9 57.0 35.0 18.1 48.3 147.7 105.1 33.4 49.5 25.6 221.9 345.5 103.0 57.3 46.0 41.9 176.6 42.0 27.5 68.8 43.3 158.4 50.0 192.0 172.5 57.5 NEUROG3 "Atoh5, bHLHa7, Math4B, ngn3" ENSG00000122859 "Neurogenin 3" Q9Y4Z2 10 69571698-69573422 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 5.4;intestine: 2.6" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 9.5;Enteroendocrine cells: 5.3" "Cancer enhanced" "Detected in some" "stomach cancer: 1.4" "Group enriched" "Detected in some" 20 "cerebral cortex: 4.5;hippocampal formation: 5.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "THP-1: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA039785 Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" Nucleoplasm "HPA039785: AB_10795114" "unprognostic (1.22e-2)" "unprognostic (7.33e-2)" "unprognostic (3.04e-2)" "unprognostic (2.42e-1)" "unprognostic (1.10e-1)" "unprognostic (1.65e-2)" "unprognostic (5.85e-5)" "unprognostic (4.58e-2)" "unprognostic (4.19e-1)" 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.6 2.6 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 4.5 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 NFAM1 CNAIP ENSG00000235568 "NFAT activating protein with ITAM motif 1" Q8NET5 22 42380407-42432403 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.9;lymphoid tissue: 19.9" "Cell type enhanced" "Detected in some" "granulocytes: 11.4;Hofbauer cells: 17.0;Kupffer cells: 53.9;Macrophages: 27.2;monocytes: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 90.4" "Group enriched" "Detected in many" 4 "granulocytes: 90.4;monocytes: 48.2" "Cell line enriched" "Detected in some" 4 "THP-1: 37.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031812 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA031812: AB_10603121" "unprognostic (9.77e-3)" "unprognostic (2.77e-3)" "unprognostic (8.21e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.83e-2)" "unprognostic (8.76e-3)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (9.12e-3)" "unprognostic (9.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (8.12e-3)" "unprognostic (1.75e-1)" "unprognostic (4.42e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" 6.3 1.9 1.5 12.4 1.9 30.9 1.1 1.5 2.2 1.8 2.0 1.5 1.3 0.6 0.6 1.3 2.0 2.3 1.3 1.8 2.4 1.2 2.3 7.5 5.5 3.1 2.2 0.3 0.8 0.3 0.6 2.9 2.9 0.9 1.2 0.1 0.8 1.4 0.4 1.4 2.3 2.9 2.3 19.9 1.1 0.7 2.9 2.1 0.7 1.5 2.1 3.1 0.7 3.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 8.8 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 5.8 0.0 0.0 0.1 0.0 0.4 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.3 48.2 2.8 0.1 32.5 0.2 0.0 0.1 0.0 16.5 0.1 0.0 0.0 90.4 0.0 31.1 0.3 0.0 25.4 1.5 1.9 1.5 2.2 1.8 2.4 3.1 2.2 2.9 2.3 2.9 3.0 0.4 0.0 3.7 0.0 0.5 0.9 0.7 0.9 0.6 0.2 0.4 0.0 0.6 1.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.8 0.4 0.2 0.5 1.2 0.0 0.7 0.2 0.1 0.5 0.0 0.3 11.4 0.0 0.7 0.6 17.0 0.0 0.6 0.0 0.0 53.9 8.2 5.6 0.3 27.2 0.0 8.4 44.6 0.0 0.0 2.0 0.5 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.5 0.5 0.8 0.7 0.0 1.0 0.3 1.3 0.4 0.0 0.5 NFYC "CBF-C, NF-YC" ENSG00000066136 "Nuclear transcription factor Y subunit gamma" Q13952 1 40691648-40771603 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "THP-1: 347.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055011 Supported Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA055011: AB_2682671" "unprognostic (1.20e-3)" "unprognostic (1.51e-2)" "unprognostic (9.77e-2)" "unprognostic (1.37e-3)" "unprognostic (8.53e-2)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.24e-4)" "unprognostic (1.47e-2)" "unprognostic (5.66e-3)" "unprognostic (3.53e-3)" "unprognostic (2.75e-1)" "unprognostic (2.60e-2)" "prognostic favorable (1.24e-4)" "unprognostic (2.25e-2)" "unprognostic (3.63e-1)" "unprognostic (3.12e-1)" "unprognostic (7.75e-3)" 27.2 26.9 29.4 29.8 30.6 40.6 29.6 37.7 35.3 31.9 37.2 31.3 28.9 32.4 24.0 33.6 31.1 23.7 60.8 31.0 28.9 31.8 33.8 24.3 37.1 28.6 29.6 40.6 32.7 50.2 20.9 30.2 28.5 25.8 23.5 27.7 46.7 24.5 72.9 42.9 29.6 28.9 28.0 39.7 31.2 22.7 31.4 41.1 34.8 63.5 33.8 29.4 30.3 33.8 34.7 46.6 67.3 51.0 26.6 24.1 67.2 28.3 31.5 49.4 46.2 65.4 85.7 83.0 43.2 27.1 43.7 40.8 54.6 42.5 51.5 50.6 57.7 90.1 33.8 59.9 31.6 48.0 73.8 26.8 45.2 48.9 51.4 38.0 32.6 62.4 40.3 51.5 23.7 47.6 86.6 47.3 58.2 41.4 36.0 64.2 71.7 74.9 46.6 41.9 45.8 42.4 33.9 73.4 77.4 77.2 33.3 347.6 29.8 22.9 77.9 40.5 42.4 47.6 84.0 68.9 53.2 61.1 62.8 54.8 61.8 64.7 28.4 69.3 29.2 47.0 37.6 32.2 59.8 43.1 40.3 30.5 103.2 41.3 81.1 46.2 44.2 41.0 29.4 30.6 37.7 35.3 31.0 28.9 28.6 29.6 28.5 28.0 31.4 33.8 27.3 19.2 21.3 51.6 40.0 29.2 28.1 25.5 31.3 18.6 22.6 24.5 32.6 15.7 20.6 11.0 10.4 74.4 22.6 23.7 37.2 27.6 9.2 14.8 22.0 29.0 16.3 39.5 37.6 37.5 51.9 21.7 25.5 21.7 38.0 25.2 26.0 23.1 51.9 25.2 46.8 21.9 30.5 30.5 31.6 6.2 27.7 33.0 17.8 49.6 44.2 29.3 25.7 39.2 41.9 26.8 18.7 21.4 33.6 19.6 25.2 22.3 10.7 12.6 19.7 24.0 27.5 43.8 39.1 27.3 32.4 76.1 30.2 27.7 27.4 25.1 NLRP3 "AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, DFNA34, FCAS, FCU, MWS, NALP3, PYPAF1" ENSG00000162711 "NLR family pyrin domain containing 3" Q96P20 1 247416156-247449108 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" Activator "Amyloidosis, Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 53.8" "Cell type enriched" "Detected in many" 6 "Macrophages: 254.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 129.4" "Group enriched" "Detected in many" 23 "dendritic cells: 37.3;granulocytes: 129.4;monocytes: 35.6" "Cell line enriched" "Detected in some" 4 "THP-1: 78.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA012878 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA012878: AB_1846752" "unprognostic (3.56e-2)" "unprognostic (1.33e-1)" "unprognostic (6.23e-2)" "unprognostic (3.96e-2)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (7.86e-2)" "unprognostic (4.46e-2)" "unprognostic (3.84e-1)" "unprognostic (7.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.11e-1)" "unprognostic (1.52e-2)" "unprognostic (4.88e-3)" "unprognostic (2.17e-4)" "unprognostic (1.10e-1)" "unprognostic (6.10e-2)" 8.3 1.4 1.0 10.0 0.8 53.8 3.5 0.8 1.0 1.8 0.8 1.5 0.8 0.9 0.4 2.7 1.4 6.5 1.0 0.9 1.6 0.6 2.1 4.6 2.5 2.0 1.4 0.7 1.6 0.9 0.5 3.4 2.1 0.8 1.8 0.3 0.8 0.7 0.5 0.4 2.4 4.8 1.9 4.6 1.4 0.3 1.6 1.7 1.0 0.5 1.7 6.4 0.4 3.4 7.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.9 0.2 0.4 0.0 0.3 0.0 0.3 0.0 0.5 0.0 0.0 2.2 2.9 0.5 0.0 1.3 0.2 0.0 0.0 5.3 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.8 0.0 0.0 0.4 0.4 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 78.4 0.1 3.2 2.5 0.0 0.2 0.0 0.0 0.0 7.2 18.9 2.4 129.4 35.6 0.2 0.6 21.7 1.7 0.0 2.9 1.2 37.3 0.1 1.1 0.7 8.6 0.0 11.5 1.8 0.1 12.2 1.0 0.8 0.8 1.0 0.9 1.6 2.0 1.4 2.1 1.9 1.6 3.4 2.2 0.0 0.5 0.3 2.6 1.0 0.1 0.0 0.6 0.3 0.6 1.1 0.6 0.0 0.0 0.0 0.0 0.7 6.0 0.0 0.0 0.0 0.3 0.1 0.5 2.3 0.0 1.7 2.6 0.0 0.4 1.2 1.5 0.1 2.5 0.2 0.4 0.3 16.2 0.0 1.2 0.2 0.0 35.4 41.4 0.2 0.0 254.2 0.0 17.8 14.5 0.7 1.0 1.0 0.4 0.1 0.0 0.4 4.0 0.0 0.0 0.2 0.0 0.4 0.0 1.0 1.1 0.4 0.4 1.3 0.6 1.4 10.2 0.1 0.0 0.0 NSA2 "FLJ94393, HCLG1, HUSSY-29, TINP1" ENSG00000164346 "NSA2 ribosome biogenesis factor" O95478 5 74766991-74780113 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043487 Approved Enhanced Nucleoplasm,Nucleoli No No "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Nucleoli" "HPA043487: AB_2678507" "unprognostic (4.79e-3)" "unprognostic (1.92e-1)" "unprognostic (5.49e-2)" "unprognostic (7.80e-2)" "unprognostic (1.54e-1)" "unprognostic (4.07e-2)" "unprognostic (6.14e-3)" "unprognostic (4.24e-1)" "unprognostic (2.15e-2)" "unprognostic (9.14e-2)" "unprognostic (8.66e-2)" "unprognostic (1.03e-1)" "unprognostic (4.92e-2)" "unprognostic (3.98e-1)" "unprognostic (1.64e-1)" "unprognostic (2.31e-2)" "unprognostic (1.44e-1)" 32.0 36.5 17.1 33.2 18.9 39.3 28.7 19.3 22.2 43.7 15.6 36.4 30.4 29.9 25.0 26.7 35.0 12.2 28.3 17.4 19.0 30.9 26.6 20.3 36.9 19.1 17.9 60.4 37.7 20.6 28.1 17.3 19.2 28.5 22.8 22.6 28.1 11.5 67.9 22.2 26.0 16.9 19.9 25.8 31.2 31.8 18.2 23.5 22.1 19.0 32.0 35.9 30.6 20.4 65.2 35.4 42.5 57.6 26.6 48.9 64.8 45.8 24.5 29.5 24.9 61.2 62.3 53.0 94.0 27.3 70.2 39.6 34.6 51.9 41.9 36.1 53.7 27.9 65.8 68.3 24.8 47.9 61.7 32.4 48.2 39.8 29.6 46.5 25.5 47.3 28.0 42.8 32.2 50.1 81.4 120.4 28.3 27.8 29.9 58.4 49.8 100.5 37.7 70.9 45.3 58.5 27.8 52.8 135.7 32.6 49.5 135.8 28.0 22.0 67.4 41.8 133.3 42.7 61.1 90.0 54.6 84.3 33.3 9.3 12.1 7.5 16.3 20.6 23.5 27.1 24.6 24.7 18.5 19.5 28.7 29.8 2.2 21.4 15.9 17.2 26.4 10.3 17.1 18.9 19.3 22.2 17.4 19.0 19.1 17.9 19.2 19.9 18.2 20.4 125.8 80.1 95.9 6.5 237.4 94.1 162.1 95.9 215.1 34.6 164.2 218.3 83.7 140.2 94.5 62.5 14.6 142.3 183.7 122.9 150.6 143.1 418.6 145.2 303.6 101.1 139.6 129.2 13.1 237.9 196.2 107.6 112.1 192.8 119.2 165.4 129.2 207.7 137.4 50.5 13.2 234.6 52.9 233.2 100.2 159.1 278.4 161.9 83.6 7.5 229.6 85.8 188.4 10.1 13.4 181.2 147.9 171.5 139.4 144.4 147.5 281.7 55.9 37.7 138.1 132.8 138.0 250.2 96.3 171.7 86.0 135.4 176.1 176.8 246.1 192.5 NUDT7 ENSG00000140876 "Nudix hydrolase 7" P0C024 16 77722492-77742260 "Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 70.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 58.7;Proximal tubular cells: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 49.7;U-698: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042042 Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" Nucleoplasm "HPA042042: AB_10806232" "unprognostic (1.92e-1)" "unprognostic (1.17e-2)" "unprognostic (6.64e-2)" "unprognostic (5.95e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.84e-4)" "unprognostic (2.48e-1)" "unprognostic (4.05e-2)" "unprognostic (2.11e-1)" "unprognostic (2.46e-2)" "unprognostic (4.74e-2)" "unprognostic (4.52e-1)" "prognostic favorable (5.36e-11)" "unprognostic (1.19e-1)" "unprognostic (8.96e-2)" "unprognostic (1.32e-1)" "unprognostic (3.42e-2)" 14.4 23.6 5.9 5.2 6.0 2.2 9.2 6.4 7.4 5.8 15.6 12.0 10.8 7.8 17.5 6.6 10.2 6.8 37.6 5.6 7.8 22.1 70.1 6.1 8.9 5.5 5.4 7.3 9.5 16.3 6.0 4.5 6.0 6.6 12.3 9.7 9.0 7.2 8.1 9.0 8.7 7.4 5.3 7.0 7.5 8.7 6.8 6.4 11.8 12.1 9.1 8.2 5.8 6.1 2.1 7.0 6.2 3.5 28.4 7.2 5.8 1.8 9.1 2.7 3.5 2.0 8.8 10.3 6.6 6.9 6.5 6.9 4.7 7.6 1.6 3.3 6.4 0.1 0.4 9.6 3.1 7.1 1.4 12.2 9.4 1.5 5.3 1.2 4.8 14.7 7.6 4.4 1.1 19.1 3.7 16.8 6.6 12.4 1.7 7.8 0.8 3.1 14.1 0.0 5.1 5.0 6.5 2.6 5.7 10.6 18.6 49.7 3.7 3.1 0.4 1.4 0.3 0.0 0.0 40.6 12.1 8.8 0.0 3.8 12.4 1.7 12.6 17.5 14.4 14.2 14.8 15.1 10.2 19.8 19.5 13.5 2.0 3.5 17.5 11.7 31.5 8.8 5.9 6.0 6.4 7.4 5.6 7.8 5.5 5.4 6.0 5.3 6.8 6.1 8.3 16.0 8.7 12.7 4.1 9.7 6.5 14.6 14.2 2.5 10.9 14.5 17.9 18.6 7.9 14.7 0.0 20.3 7.9 12.1 58.7 8.0 11.6 19.5 4.7 8.2 6.7 3.6 4.3 9.5 9.1 8.5 3.6 6.6 1.3 7.0 5.3 41.2 5.9 6.7 5.6 6.6 10.2 9.2 4.4 4.6 5.6 4.1 8.8 1.9 2.1 25.0 10.3 3.5 2.7 4.0 10.4 4.9 1.1 2.0 22.6 42.2 21.0 7.3 6.6 7.1 8.9 14.2 20.0 12.2 13.9 6.7 6.9 10.7 14.8 4.5 NUP42 "CG1, H_RG271G13.9, hCG1, NLP_1, NUPL2" ENSG00000136243 "Nucleoporin 42" O15504 7 23181841-23201011 "Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 7.7;Cardiomyocytes: 20.3;Cytotrophoblasts: 17.1;dendritic cells: 10.5;Extravillous trophoblasts: 11.6;Hofbauer cells: 28.1;Syncytiotrophoblasts: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049036, HPA057251" Supported Nucleoplasm No No "Cluster 17: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA049036: , HPA057251: " "unprognostic (3.81e-2)" "unprognostic (2.53e-1)" "unprognostic (3.97e-1)" "unprognostic (3.87e-1)" "unprognostic (4.16e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-3)" "unprognostic (2.16e-1)" "unprognostic (1.09e-2)" "unprognostic (1.42e-2)" "unprognostic (1.30e-3)" "unprognostic (2.07e-2)" "unprognostic (4.74e-3)" "unprognostic (1.32e-1)" "unprognostic (2.00e-3)" "unprognostic (3.59e-1)" "unprognostic (1.32e-2)" 10.8 14.7 12.9 10.8 8.8 20.6 11.4 21.2 13.8 11.2 18.0 11.1 14.9 14.2 15.1 13.6 12.9 13.1 19.7 11.2 10.4 15.1 13.9 10.0 21.6 11.6 9.9 12.0 6.2 17.1 6.4 8.6 8.9 12.1 14.3 8.2 10.7 10.1 11.6 16.4 12.4 15.0 3.6 15.8 11.6 18.9 10.7 19.4 14.4 9.0 18.3 13.2 7.7 22.6 31.1 14.0 21.5 44.5 21.3 25.0 17.8 23.1 16.6 25.2 26.4 21.2 31.9 52.4 22.0 16.1 54.1 41.6 37.9 17.2 32.6 15.9 39.0 32.0 36.5 21.7 24.6 67.4 47.1 11.6 25.5 21.8 14.5 20.4 29.0 22.0 58.9 31.4 25.5 7.7 32.5 54.6 45.1 38.4 21.9 31.6 19.0 40.5 27.1 21.6 33.2 31.2 22.9 14.0 44.9 41.2 17.0 86.3 21.6 16.5 21.8 28.3 39.7 44.9 64.8 52.3 17.6 46.7 44.4 33.2 10.3 8.1 11.0 10.1 10.7 18.8 12.8 12.1 15.0 13.6 10.6 12.7 8.0 17.8 9.3 14.4 16.2 11.1 12.9 8.8 21.2 13.8 11.2 10.4 11.6 9.9 8.9 3.6 10.7 22.6 7.7 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.3 0.0 0.0 0.0 0.0 17.1 10.5 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 11.6 5.2 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 6.6 1.3 0.0 0.0 0.0 OAZ1 "AZ1, AZI, MGC138338, OAZ" ENSG00000104904 "Ornithine decarboxylase antizyme 1" P54368 19 2269509-2273490 "Plasma proteins, Predicted intracellular proteins" "Polyamine biosynthesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009291 Uncertain Approved "Vesicles,Centriolar satellite" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "Centriolar satellite" "HPA009291: AB_1079519" "unprognostic (2.37e-1)" "unprognostic (9.69e-3)" "unprognostic (1.72e-1)" "unprognostic (6.04e-3)" "unprognostic (9.41e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (3.75e-2)" "unprognostic (3.19e-2)" "unprognostic (6.22e-2)" "prognostic favorable (4.10e-5)" "unprognostic (3.58e-2)" "unprognostic (2.40e-1)" "unprognostic (8.37e-2)" "unprognostic (1.72e-1)" "unprognostic (2.44e-2)" "unprognostic (6.01e-2)" 201.8 252.4 114.7 170.0 125.3 330.3 177.6 107.3 189.7 143.2 111.9 204.3 161.5 134.3 91.4 167.2 151.5 109.0 289.8 132.7 121.1 203.4 172.7 194.2 244.7 119.7 122.1 139.9 209.8 46.5 173.4 134.2 117.0 150.9 77.8 36.4 226.8 89.2 525.6 177.4 197.7 85.1 116.0 294.9 188.3 67.5 120.1 68.0 144.6 123.4 138.3 170.7 152.7 113.9 577.1 117.7 88.3 152.7 181.1 287.5 228.9 400.4 275.4 197.9 269.7 169.5 181.2 389.7 210.6 187.6 78.3 163.1 87.7 120.8 129.6 523.1 303.3 301.2 108.7 267.3 184.6 425.7 456.4 192.6 207.3 74.8 112.7 177.8 227.4 141.3 297.8 439.1 226.1 210.8 357.1 442.7 291.5 83.5 210.7 291.3 176.1 519.0 184.3 164.0 207.9 220.2 264.0 236.7 464.8 70.6 198.4 890.0 293.1 140.2 173.9 610.5 427.8 423.8 188.0 468.9 636.6 660.5 217.3 1887.3 1649.6 1940.9 466.4 1685.5 469.7 962.1 506.3 502.1 1155.4 941.6 464.3 466.0 2063.4 366.1 2039.6 778.3 779.9 2803.0 114.7 125.3 107.3 189.7 132.7 121.1 119.7 122.1 117.0 116.0 120.1 113.9 492.6 365.4 510.0 54.5 1096.3 1476.0 1102.4 828.6 715.9 325.4 748.2 626.1 746.8 579.0 543.0 294.3 106.3 1065.2 1149.3 1018.3 1230.6 1043.4 95.1 452.9 335.6 591.2 613.7 1446.6 85.6 1018.2 1605.0 711.4 305.3 325.4 713.5 385.8 529.0 773.2 2248.7 222.1 78.6 816.9 547.3 2400.4 2984.5 286.7 558.6 2391.4 1136.6 60.0 2929.3 362.0 1001.1 46.3 62.2 1071.2 1388.3 477.3 1143.0 1314.8 1700.6 1540.0 553.2 285.5 460.2 487.9 821.8 251.8 256.5 751.8 1283.3 1683.5 911.1 666.9 733.6 1692.6 OOSP1 ENSG00000284873 "Oocyte secreted protein 1" 11 59938432-59957480 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.2;Inhibitory neurons: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "THP-1: 1.2" "Not detected" "Not detected" NA NA "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR2B11 ENSG00000177535 "Olfactory receptor family 2 subfamily B member 11" Q5JQS5 1 247449118-247458105 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "Alveolar cells type 2: 2.2;Club cells: 5.0;granulocytes: 3.8;Macrophages: 2.2;Respiratory ciliated cells: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "THP-1: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA047459 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA047459: AB_10963692" "unprognostic (1.83e-1)" 0.1 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 OTX1 ENSG00000115507 "Orthodenticle homeobox 1" P32242 2 63050057-63057836 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "salivary gland: 18.0;skin 1: 8.4" "Cell type enhanced" "Detected in some" "Astrocytes: 9.8;Basal respiratory cells: 6.3;Club cells: 4.1;Ionocytes: 6.1;Respiratory ciliated cells: 6.8;Suprabasal keratinocytes: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 95 "neutrophil: 9.4" "Lineage enriched" "Detected in single" 95 "granulocytes: 9.4" "Cell line enriched" "Detected in many" 9 "THP-1: 54.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052122 Uncertain Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA052122: AB_2681736" "unprognostic (2.25e-2)" "unprognostic (1.03e-1)" "unprognostic (1.19e-1)" "unprognostic (2.36e-3)" "unprognostic (2.32e-1)" "unprognostic (1.67e-2)" "unprognostic (6.92e-3)" "unprognostic (3.66e-2)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (2.26e-3)" "unprognostic (1.71e-1)" "unprognostic (0.00e+0)" "unprognostic (4.64e-2)" "unprognostic (2.31e-1)" "unprognostic (3.80e-4)" "unprognostic (3.67e-3)" 0.1 0.0 2.1 0.0 1.7 0.0 0.2 0.1 2.5 0.0 3.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.1 0.0 0.2 2.5 0.0 0.2 0.0 0.0 0.0 0.7 0.7 0.0 0.0 18.0 0.0 0.0 8.4 0.0 0.0 0.0 0.1 0.2 0.3 2.8 0.0 0.0 0.0 0.5 0.0 0.1 1.8 2.3 1.3 4.2 2.5 0.0 0.1 5.9 0.0 0.3 0.3 0.4 4.4 2.2 0.1 0.8 0.0 1.1 3.0 2.7 1.9 0.5 1.1 2.5 2.7 2.2 5.0 0.0 1.9 2.0 0.0 0.7 0.0 0.7 0.8 0.0 2.6 2.4 0.0 0.2 2.1 2.6 4.6 0.0 2.2 1.6 2.3 3.6 0.7 1.2 0.8 0.4 0.5 1.8 0.2 1.5 0.0 1.0 54.1 0.1 0.9 1.7 0.0 0.9 1.5 1.1 4.0 0.3 2.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 2.1 1.7 0.1 2.5 1.9 1.4 0.2 2.5 0.7 0.0 2.8 1.8 0.2 0.0 0.0 9.8 0.1 1.7 0.0 6.3 0.6 0.0 0.8 1.0 0.8 0.0 4.1 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.2 0.6 1.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 6.8 0.0 0.0 0.7 0.3 0.3 0.5 1.1 2.6 0.1 0.0 0.1 0.2 0.1 P2RY2 P2U ENSG00000175591 "Purinergic receptor P2Y2" P41231 11 73218281-73242427 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.7;skeletal muscle: 50.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.5;Distal enterocytes: 18.0;Pancreatic endocrine cells: 18.9;Proximal enterocytes: 14.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 57.6" "Group enriched" "Detected in many" 12 "granulocytes: 57.6;monocytes: 20.2" "Cell line enhanced" "Detected in many" "HaCaT: 32.8;HL-60: 30.8;MCF7: 25.1;NB-4: 26.1;PC-3: 24.5;SK-BR-3: 29.6;THP-1: 76.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB022642 Uncertain Uncertain Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB022642: " "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (6.50e-4)" "unprognostic (2.04e-2)" "unprognostic (4.66e-3)" "unprognostic (8.93e-2)" "unprognostic (2.87e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (9.69e-2)" "unprognostic (4.92e-4)" "unprognostic (1.34e-1)" "unprognostic (2.82e-1)" "unprognostic (1.05e-1)" "unprognostic (8.57e-3)" 0.8 3.8 1.4 1.8 1.6 15.8 1.7 1.3 1.0 6.9 1.1 3.3 2.7 0.5 0.3 29.7 1.4 0.7 10.0 1.3 1.8 2.7 3.9 3.5 0.1 2.1 1.9 0.4 0.7 4.8 1.6 2.0 1.6 2.1 2.8 1.2 6.2 1.2 50.2 6.0 5.9 0.5 1.3 3.9 1.1 1.2 2.6 0.2 8.8 31.3 2.8 2.2 19.0 1.4 7.2 6.7 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.0 17.2 5.4 0.0 10.4 0.4 0.0 32.8 0.9 15.2 0.0 0.0 0.6 2.3 0.6 3.2 0.1 30.8 0.0 0.0 6.8 2.3 0.5 0.0 1.4 0.0 1.4 0.0 0.0 25.1 0.1 26.1 0.4 6.8 24.5 0.0 0.0 1.1 2.4 17.9 0.0 0.0 0.5 29.6 0.0 0.2 12.9 76.5 10.2 0.0 0.3 0.0 0.0 1.0 0.4 0.0 0.0 5.6 0.0 0.5 6.6 57.6 0.0 20.2 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.0 13.5 0.0 0.0 2.5 1.4 1.6 1.3 1.0 1.3 1.8 2.1 1.9 1.6 1.3 2.6 1.4 0.7 3.2 0.5 0.0 0.2 3.7 8.6 13.2 1.2 0.7 2.8 0.5 6.1 5.7 10.3 0.0 0.0 16.5 0.0 18.0 1.9 5.8 6.0 1.4 0.1 1.5 0.0 0.8 0.0 6.3 1.3 0.7 0.5 0.8 0.0 1.2 0.0 5.2 2.6 0.0 0.0 5.1 0.0 3.7 0.7 8.8 0.0 4.5 0.0 0.0 2.8 6.0 0.0 0.0 0.1 18.9 10.9 0.0 0.2 5.3 14.2 0.3 2.8 0.4 0.0 0.8 1.4 0.1 0.1 12.6 7.2 10.9 0.1 0.1 3.0 11.7 P4HB "DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB" ENSG00000185624 "Prolyl 4-hydroxylase subunit beta" P07237 17 81843159-81860856 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chaperone, Isomerase" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1856.8;pancreas: 2446.9" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 1077.9;Extravillous trophoblasts: 1349.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012463, HPA018884" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No No 110000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB012463: , HPA018884: AB_1854896" "unprognostic (9.47e-3)" "unprognostic (1.09e-2)" "unprognostic (2.99e-2)" "unprognostic (7.14e-3)" "unprognostic (7.75e-3)" "unprognostic (1.05e-2)" "unprognostic (1.30e-1)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (4.73e-3)" "unprognostic (1.43e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (2.30e-11)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (4.99e-3)" "unprognostic (3.19e-3)" 266.5 507.8 34.6 209.8 35.7 517.1 225.5 39.1 35.7 272.0 59.6 258.4 640.2 206.5 133.0 618.7 183.4 202.0 318.4 31.7 50.2 270.7 1856.8 301.3 104.0 48.9 37.1 187.8 2446.9 144.3 330.0 334.3 40.8 335.8 173.6 23.3 948.1 184.2 328.5 370.4 554.7 179.8 39.8 428.6 539.2 68.8 58.7 89.3 244.8 150.8 137.9 233.7 322.9 43.7 690.3 580.7 236.8 687.5 813.4 726.7 593.6 1038.5 1081.1 741.9 934.5 550.4 576.9 264.4 501.8 1120.2 407.5 464.1 248.8 647.4 254.1 145.8 320.5 355.2 362.9 953.6 1010.8 1146.4 613.4 618.8 494.8 478.2 596.7 843.0 1250.1 182.1 273.6 978.2 559.5 566.4 260.5 723.2 157.7 791.0 463.8 261.8 342.5 614.0 453.2 492.8 248.7 301.1 586.1 1693.1 808.1 289.6 855.3 1601.2 644.1 980.5 503.1 574.3 586.6 743.5 407.9 204.8 1372.0 591.3 825.4 198.3 268.1 163.0 202.6 154.4 209.8 83.9 138.9 165.7 174.7 68.1 74.9 114.6 72.9 157.0 115.3 311.5 105.6 372.4 34.6 35.7 39.1 35.7 31.7 50.2 48.9 37.1 40.8 39.8 58.7 43.7 122.3 102.5 162.1 23.2 151.4 120.1 163.6 371.0 140.6 59.2 283.0 170.8 24.1 247.4 211.7 112.2 33.3 790.2 208.9 420.7 41.1 671.9 43.5 78.4 196.8 153.9 199.9 140.9 15.3 1077.9 1349.1 272.5 388.9 209.1 99.1 210.4 190.2 840.7 435.9 62.2 16.2 610.9 189.2 186.9 125.5 64.9 141.4 180.3 136.9 20.6 263.3 122.7 230.7 13.6 19.6 575.2 465.6 112.1 664.3 310.6 914.2 105.0 91.3 54.3 157.8 103.4 226.7 83.4 94.1 302.3 144.6 1001.2 138.8 378.4 475.4 220.8 PARP8 "ARTD16, FLJ21308, pART16" ENSG00000151883 "Poly(ADP-ribose) polymerase family member 8" Q8N3A8 5 50665899-50846519 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.2" "Cell type enhanced" "Detected in many" "dendritic cells: 124.9;Excitatory neurons: 197.9;Inhibitory neurons: 139.3;Microglial cells: 112.4;Oligodendrocyte precursor cells: 158.3;T-cells: 157.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 91.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049183 Approved Approved "Nucleoplasm,Midbody ring,Cytosol" Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Midbody ring, Cytosol" "HPA049183: AB_2680667" "unprognostic (1.22e-2)" "unprognostic (2.53e-1)" "unprognostic (1.77e-1)" "unprognostic (1.05e-1)" "unprognostic (2.12e-1)" "unprognostic (6.33e-2)" "unprognostic (8.86e-3)" "unprognostic (7.27e-2)" "unprognostic (1.86e-2)" "unprognostic (8.96e-2)" "unprognostic (2.85e-1)" "unprognostic (6.81e-2)" "unprognostic (9.63e-2)" "unprognostic (2.84e-2)" "unprognostic (4.42e-2)" "unprognostic (4.23e-2)" "prognostic favorable (1.12e-4)" 11.7 13.1 4.6 26.8 8.8 78.2 9.2 0.0 7.9 8.3 0.3 8.8 14.5 6.6 4.2 7.7 9.9 25.7 6.9 14.7 12.6 7.0 8.0 19.8 42.0 3.4 4.5 11.6 12.2 13.8 4.9 12.4 0.1 11.3 9.3 4.6 10.3 7.4 4.8 7.6 15.0 8.4 2.7 43.6 20.2 9.1 7.7 19.2 43.1 2.1 22.5 14.5 5.4 2.0 24.8 0.1 12.2 18.8 3.2 5.7 18.0 4.3 15.7 4.1 12.0 0.9 33.5 14.8 16.9 0.5 43.3 12.4 2.1 13.1 10.0 20.2 15.9 10.6 9.2 1.1 6.3 28.1 0.2 6.8 10.9 8.5 6.0 24.6 0.2 23.1 1.6 9.1 5.9 8.8 31.8 32.5 12.3 0.4 6.0 15.4 24.0 17.1 7.6 12.8 13.0 19.0 13.8 21.6 3.7 17.6 1.0 91.2 0.0 1.0 15.4 1.2 12.6 6.9 0.2 29.5 13.8 7.6 17.7 27.4 13.7 31.9 43.6 4.0 70.6 13.4 34.3 50.5 9.2 16.7 20.9 34.9 28.6 39.5 2.9 4.2 22.5 22.7 4.6 8.8 0.0 7.9 14.7 12.6 3.4 4.5 0.1 2.7 7.7 2.0 6.2 32.1 21.1 29.4 51.7 8.0 5.2 12.7 26.2 13.6 10.4 6.5 5.6 14.3 19.1 22.0 0.0 22.5 124.9 17.2 7.9 14.2 28.7 11.8 8.4 3.9 15.0 7.4 197.9 10.2 6.4 13.4 46.9 10.6 14.5 12.6 6.8 5.0 14.3 6.7 139.3 4.2 8.2 26.1 16.9 15.3 1.2 27.1 8.8 112.4 43.4 0.7 93.7 158.3 7.3 18.7 8.4 3.0 65.0 7.7 8.2 4.3 25.6 2.1 6.6 12.3 13.0 12.8 6.0 14.3 4.0 24.8 157.3 6.5 9.6 13.7 PBX3 ENSG00000167081 "PBX homeobox 3" P40426 9 125747345-125967377 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 153.1" "Cell type enhanced" "Detected in many" "Microglial cells: 91.8;Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 192.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 39.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 13.9" "Lineage enriched" "Detected in all" 4 "dendritic cells: 13.9" "Cell line enhanced" "Detected in many" "THP-1: 90.1" "Region enhanced" "Detected in all" "olfactory bulb: 167.4" "Group enriched" "Detected in all" 5 "basal ganglia: 46.3;olfactory bulb: 161.9" HPA003881 Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA003881: AB_1855020" "unprognostic (1.97e-2)" "unprognostic (3.78e-2)" "unprognostic (1.15e-1)" "unprognostic (1.93e-2)" "unprognostic (1.27e-1)" "unprognostic (2.35e-1)" "unprognostic (2.20e-1)" "unprognostic (3.38e-2)" "unprognostic (2.83e-1)" "unprognostic (2.88e-1)" "unprognostic (2.42e-3)" "unprognostic (7.02e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-2)" "unprognostic (1.63e-1)" "unprognostic (8.03e-2)" "unprognostic (6.29e-2)" 10.9 56.0 10.4 12.9 14.6 6.9 10.0 17.4 13.2 27.2 7.0 47.9 6.8 9.8 20.0 11.8 14.2 22.5 38.0 7.2 15.0 7.1 18.1 13.0 8.0 19.7 21.0 58.2 18.8 153.1 12.6 6.7 19.4 30.9 13.7 28.0 11.8 28.0 8.5 19.4 14.3 22.6 18.8 12.8 21.5 8.2 15.3 16.7 35.1 5.7 6.9 20.7 21.9 21.7 11.6 11.0 50.0 43.1 13.1 19.1 8.5 29.9 16.8 19.2 14.5 14.3 21.1 11.3 3.6 22.1 20.8 8.5 28.3 12.3 38.3 12.4 20.5 9.7 7.9 5.8 17.2 9.6 15.5 9.5 13.7 14.5 10.0 45.3 23.1 7.2 0.4 10.3 43.5 5.9 10.0 4.9 35.8 14.2 7.4 18.9 73.3 1.5 15.6 6.4 25.9 45.1 20.2 3.8 9.4 18.8 15.7 90.1 26.6 40.0 10.2 23.8 57.1 7.2 12.8 11.5 19.7 15.2 20.6 2.3 1.7 2.2 0.8 1.4 0.9 1.0 0.9 0.7 1.9 1.5 1.7 0.7 1.4 3.2 1.3 13.9 0.8 1.0 10.4 14.6 17.4 13.2 7.2 15.0 19.7 21.0 19.4 18.8 15.3 21.7 7.3 9.6 16.7 17.9 10.0 22.7 10.3 3.0 6.8 7.5 11.5 8.3 60.3 2.8 8.6 12.9 37.5 0.6 20.7 1.3 7.9 13.5 15.2 1.1 14.0 11.9 11.5 6.3 44.3 2.5 0.9 23.4 5.6 1.5 16.5 9.4 9.7 12.6 15.3 42.1 19.3 5.7 6.1 29.0 23.7 11.4 19.9 22.9 7.2 91.8 13.6 11.5 6.2 136.2 192.2 3.1 12.1 11.3 3.8 13.0 0.9 2.8 8.5 43.1 0.0 5.3 13.0 33.7 16.0 10.4 26.3 0.4 10.5 8.7 3.4 8.7 PCID2 FLJ11305 ENSG00000126226 "PCI domain containing 2" Q5JVF3 13 113177536-113208715 "Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 204.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069107, HPA073074" Uncertain Approved Nucleoplasm,Nucleoli NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA069107: AB_2686088, HPA073074: AB_2686568" "unprognostic (2.53e-2)" "unprognostic (2.94e-2)" "unprognostic (4.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (7.80e-5)" "unprognostic (1.73e-3)" "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (1.47e-1)" "unprognostic (3.02e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.24e-6)" "unprognostic (1.41e-2)" "unprognostic (5.41e-3)" "unprognostic (1.45e-1)" "unprognostic (6.28e-2)" 22.2 29.0 16.6 15.8 17.4 15.5 22.9 19.0 18.8 27.0 18.3 25.2 12.1 23.0 23.0 19.3 25.9 17.1 37.7 16.8 17.3 20.1 23.8 18.6 25.8 16.4 16.6 33.7 23.9 19.1 22.6 15.5 16.4 24.7 18.5 10.7 23.8 19.2 29.1 18.9 20.2 21.8 16.5 24.7 24.4 45.3 17.6 24.4 20.8 24.4 23.0 23.9 22.4 18.8 62.9 26.3 39.1 34.7 70.2 52.3 27.4 47.2 70.7 64.4 59.1 51.9 57.7 50.2 30.7 64.5 81.6 38.8 62.9 42.8 71.2 44.3 62.1 64.8 68.1 45.9 70.0 110.4 25.5 43.3 46.6 40.4 71.1 51.4 51.3 68.5 50.4 19.9 73.6 30.3 59.4 77.9 38.9 115.1 33.2 53.4 43.4 48.0 58.8 31.3 52.0 31.9 29.5 72.2 55.9 39.3 39.9 133.4 33.5 19.0 68.7 27.9 36.2 30.4 30.4 70.4 65.3 74.1 44.2 28.2 25.5 20.0 68.9 34.4 81.6 39.7 58.0 72.5 26.0 39.5 52.2 54.6 3.9 22.6 33.2 24.8 64.7 54.7 16.6 17.4 19.0 18.8 16.8 17.3 16.4 16.6 16.4 16.5 17.6 18.8 26.5 19.2 16.7 16.3 28.4 21.5 29.1 37.8 17.6 23.6 25.5 32.3 27.8 21.5 23.7 14.7 16.7 30.2 38.5 7.8 27.4 22.8 52.8 26.8 35.7 26.2 7.8 32.8 43.6 13.8 24.7 33.8 18.8 21.7 10.8 39.0 18.9 18.4 20.2 37.0 33.7 15.6 16.2 18.2 14.0 18.1 41.3 17.2 16.0 26.2 24.0 19.0 38.1 25.1 40.4 18.1 15.8 40.6 16.8 46.3 13.6 23.6 30.4 23.8 19.7 37.4 30.9 204.4 72.7 17.6 24.7 31.1 43.7 33.0 20.1 25.3 PDYN "ADCA, PENKB, SCA23" ENSG00000101327 Prodynorphin P01213 20 1978757-1994285 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Neurotransmitter, Opioid peptide" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 47.0" "Group enriched" "Detected in some" 83 "Early spermatids: 47.8;Late spermatids: 119.0" "Group enriched" "Detected in some" 29 "glioma: 2.6;ovarian cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "THP-1: 1.0" "Group enriched" "Detected in many" 4 "basal ganglia: 152.2;hypothalamus: 60.7" "Region enhanced" "Detected in many" "basal ganglia: 132.2" "HPA053342, CAB079777" Enhanced Supported "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "CAB079777: , HPA053342: AB_2682121" "unprognostic (7.00e-2)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" "unprognostic (3.73e-2)" 0.0 0.0 43.2 0.1 31.1 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.0 17.6 0.0 0.0 0.0 0.0 1.8 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 21.0 0.0 0.0 8.3 9.2 0.2 0.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.2 31.1 0.0 43.1 47.0 17.6 1.8 4.1 0.2 21.0 9.2 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 119.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PDZD7 "bA108L7.8, DFNB57, FLJ23209, PDZK7" ENSG00000186862 "PDZ domain containing 7" Q9H5P4 10 101007679-101032295 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 21.5;intestine: 20.0;pituitary gland: 6.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 15.9;Cone photoreceptor cells: 22.9;Excitatory neurons: 32.3;Inhibitory neurons: 16.5;Proximal enterocytes: 56.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 7.5;SCLC-21H: 11.7;THP-1: 18.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074542 Supported Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 43: THP-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA074542: " "unprognostic (1.46e-1)" "unprognostic (2.85e-3)" "unprognostic (3.96e-2)" "unprognostic (2.10e-1)" "unprognostic (2.15e-2)" "unprognostic (2.83e-2)" "unprognostic (1.38e-2)" "unprognostic (5.31e-2)" "unprognostic (2.52e-2)" "unprognostic (2.95e-2)" "unprognostic (2.45e-1)" "unprognostic (1.87e-3)" "unprognostic (3.54e-3)" "unprognostic (3.89e-1)" "unprognostic (1.79e-1)" "unprognostic (3.51e-2)" "unprognostic (2.80e-1)" 1.5 1.3 5.8 1.0 8.0 1.3 0.5 10.2 15.4 0.7 0.7 0.4 12.8 1.4 0.9 0.3 0.4 1.9 0.6 5.7 4.5 1.5 0.1 1.0 0.9 21.5 7.7 0.6 0.9 1.1 6.0 1.0 21.0 0.7 0.2 2.3 1.1 0.5 0.9 2.4 20.0 1.0 2.7 1.6 1.0 1.2 8.8 0.7 1.2 0.2 0.1 0.4 0.8 9.9 7.5 0.9 0.5 0.7 0.9 0.1 2.3 1.2 0.6 0.0 0.3 1.5 1.7 3.7 3.5 0.3 1.0 2.2 0.2 0.7 0.0 1.0 2.5 0.2 3.8 2.3 0.6 0.5 3.1 0.3 0.1 0.2 0.1 4.2 0.2 3.3 0.6 0.7 0.1 1.8 0.5 1.2 0.6 1.5 2.4 1.6 1.0 0.4 1.8 0.6 11.7 5.4 0.8 0.3 1.2 1.0 2.4 18.2 0.5 1.1 2.4 1.4 1.0 1.5 0.1 0.2 6.4 1.2 0.6 0.6 0.4 0.5 0.3 0.4 0.3 0.3 0.2 0.4 0.1 0.3 0.4 0.2 1.6 0.8 0.3 0.1 0.1 0.3 5.8 8.0 10.2 15.4 5.7 4.5 21.5 7.7 21.0 2.7 8.8 9.9 0.8 0.0 0.0 1.3 0.1 0.5 0.5 0.2 0.0 15.9 0.5 0.9 1.4 2.8 0.2 1.8 22.9 0.2 0.1 0.2 1.9 0.7 1.7 2.1 0.3 0.7 0.0 0.0 32.3 0.4 5.2 0.8 1.1 0.3 0.0 1.6 0.7 0.0 2.1 1.7 16.5 1.5 0.0 1.3 2.7 2.6 0.3 1.0 0.0 5.6 0.3 0.9 1.0 0.5 6.9 1.3 1.2 1.2 0.3 0.4 56.7 1.6 1.3 8.3 0.0 1.4 1.7 2.9 3.7 0.2 0.4 1.9 0.8 0.1 1.0 0.2 PEX11B ENSG00000131779 "Peroxisomal biogenesis factor 11 beta" O96011 1 145911350-145918717 "Disease related genes, Predicted membrane proteins" "Peroxisome biogenesis" "Peroxisome biogenesis disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017150, HPA050104" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles Nucleoplasm "HPA017150: , HPA050104: AB_2681017" "unprognostic (4.59e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.29e-1)" "unprognostic (3.62e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.67e-4)" "prognostic favorable (6.85e-4)" "unprognostic (1.19e-1)" "unprognostic (4.08e-2)" "unprognostic (2.10e-1)" "unprognostic (8.48e-2)" "unprognostic (6.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (7.62e-3)" "unprognostic (4.28e-1)" 17.5 25.1 34.7 19.0 35.8 13.3 31.2 32.5 42.5 24.6 33.3 24.9 24.6 23.4 33.1 34.3 25.7 17.0 28.0 36.3 38.1 32.4 27.1 20.1 27.4 33.3 33.0 24.6 27.2 33.5 24.5 23.1 35.1 24.3 27.6 20.2 28.7 25.6 39.8 28.1 25.9 21.0 31.6 27.7 28.3 30.8 34.1 30.2 26.4 34.9 34.7 23.2 22.2 34.2 27.1 24.4 21.0 21.1 48.6 37.9 21.9 26.8 35.3 34.4 26.5 11.3 30.7 25.2 28.1 38.3 16.6 31.9 18.6 40.0 24.0 28.4 14.1 15.6 14.8 29.2 68.3 46.9 27.5 49.9 49.3 23.3 22.8 43.9 44.5 34.8 28.7 40.5 54.7 43.1 35.8 43.5 7.5 57.4 29.5 33.0 31.5 55.5 58.8 19.1 14.7 24.0 20.2 38.4 24.7 20.5 53.2 72.0 39.7 23.1 18.2 30.3 19.8 43.1 54.0 35.1 38.5 26.3 16.0 89.6 64.7 47.3 58.5 60.9 64.8 93.2 67.5 65.4 70.8 84.1 74.7 67.9 32.4 71.1 60.5 94.9 79.6 82.7 34.7 35.8 32.5 42.5 36.3 38.1 33.3 33.0 35.1 31.6 34.1 34.2 5.0 16.0 10.3 9.8 17.0 19.4 9.2 41.3 26.7 8.0 16.8 17.0 12.8 17.2 20.7 40.5 0.0 37.9 19.6 20.2 45.0 13.7 12.2 8.2 7.0 12.3 12.7 14.1 13.0 13.8 13.9 11.1 19.4 7.4 3.8 9.3 18.2 32.9 23.0 5.0 13.5 16.0 20.3 18.3 10.7 21.1 14.0 12.9 21.4 4.7 27.1 12.6 25.7 9.5 12.9 16.0 11.4 19.9 17.4 10.1 20.1 34.5 22.9 5.1 6.6 5.8 10.3 41.1 24.3 34.0 22.0 20.0 13.8 11.6 15.8 9.4 PHACTR3 "C20orf101, PPP1R123" ENSG00000087495 "Phosphatase and actin regulator 3" Q96KR7 20 59577509-59847711 "Predicted intracellular proteins" "Actin-binding, Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 104.4;choroid plexus: 36.5" "Cell type enhanced" "Detected in many" "Astrocytes: 205.7;Excitatory neurons: 100.4;Inhibitory neurons: 88.7;Oligodendrocyte precursor cells: 218.1;Oligodendrocytes: 241.1" "Group enriched" "Detected in some" 5 "glioma: 3.8;lung cancer: 1.6;pancreatic cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 85.4;HBEC3-KT: 64.6;PC-3: 113.2;THP-1: 131.3;U-937: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051834, HPA054847" Enhanced Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA051834: AB_2681629, HPA054847: " "unprognostic (7.14e-2)" "unprognostic (1.22e-1)" "unprognostic (3.72e-2)" "unprognostic (1.43e-7)" "unprognostic (1.99e-1)" "unprognostic (2.87e-2)" "unprognostic (5.83e-3)" "unprognostic (8.92e-2)" "unprognostic (5.02e-2)" "unprognostic (2.30e-2)" "unprognostic (7.71e-2)" "unprognostic (7.22e-2)" "unprognostic (1.74e-2)" "unprognostic (1.66e-1)" "unprognostic (5.43e-2)" "unprognostic (2.53e-3)" "unprognostic (1.32e-1)" 0.9 1.2 90.4 0.5 92.4 0.5 0.4 82.0 93.4 0.3 36.5 0.8 0.7 1.0 0.7 1.1 8.6 1.9 4.0 82.3 75.4 2.2 0.6 5.9 0.1 78.5 82.4 6.2 0.2 0.0 1.7 0.6 76.1 0.1 0.8 3.3 0.1 0.0 0.2 1.1 1.0 0.3 74.7 5.5 0.5 0.5 93.7 1.9 0.1 1.0 0.1 0.5 0.1 104.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 85.4 0.0 6.2 1.3 0.0 0.2 0.3 64.6 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 1.4 0.1 10.5 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 17.9 0.3 0.4 113.2 0.0 0.0 0.7 25.1 1.4 2.1 6.5 0.5 0.0 0.1 0.0 0.5 131.3 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 90.4 92.4 82.0 93.4 82.3 75.4 78.5 82.4 76.1 74.7 93.7 104.4 0.3 12.8 0.5 205.7 0.3 0.6 1.3 2.1 0.0 13.8 0.2 0.0 8.9 10.0 8.4 3.7 0.0 0.0 0.0 0.0 1.9 1.1 1.0 7.1 3.7 0.3 1.2 0.0 100.4 0.0 0.0 4.2 0.0 2.1 0.0 0.5 3.3 0.0 0.2 5.0 88.7 0.9 44.7 0.3 1.1 0.9 0.0 3.7 0.0 7.5 0.0 0.8 0.0 218.1 241.1 2.9 0.1 0.0 0.9 2.9 4.3 0.1 1.3 1.9 0.0 2.9 0.9 0.3 1.0 0.1 0.4 0.0 0.1 0.9 4.5 3.2 PIBF1 "C13orf24, CEP90" ENSG00000083535 "Progesterone immunomodulatory binding factor 1" Q8WXW3 13 72782133-73016461 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 334.5;Oligodendrocyte precursor cells: 143.7;Oligodendrocytes: 138.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052269, HPA066120" Approved Supported "Centriolar satellite" "Secreted to blood" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Centriolar satellite" "HPA052269: AB_2681779, HPA066120: AB_2685621" "unprognostic (1.54e-1)" "unprognostic (4.17e-1)" "unprognostic (6.73e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (3.80e-2)" "unprognostic (3.79e-2)" "unprognostic (3.87e-2)" "unprognostic (4.08e-2)" "unprognostic (2.62e-2)" "unprognostic (2.26e-3)" "unprognostic (1.39e-1)" "unprognostic (6.85e-3)" "unprognostic (8.31e-2)" "unprognostic (2.78e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-1)" 7.6 9.1 5.2 6.7 5.5 10.2 12.2 7.4 7.3 11.5 9.8 7.4 7.0 11.5 10.7 7.1 11.0 8.4 7.5 4.6 4.8 8.3 9.8 8.7 9.9 5.1 5.0 12.6 5.5 8.5 7.5 9.7 4.7 9.8 8.8 10.2 7.4 8.2 6.6 8.5 6.9 8.5 4.7 8.4 8.7 14.3 5.0 13.0 15.5 7.4 8.4 10.1 8.0 6.0 13.1 4.2 16.8 9.8 14.4 25.3 6.5 11.9 15.9 11.8 14.4 5.8 22.1 12.0 13.7 13.2 6.2 11.1 9.1 12.0 18.9 12.2 8.7 8.2 10.9 6.7 18.4 31.0 7.5 16.4 9.4 12.7 30.7 15.1 15.5 8.2 11.7 6.1 15.9 3.7 15.2 18.6 8.9 23.3 3.9 12.0 12.4 12.4 24.5 7.0 9.6 15.4 9.2 6.3 16.3 13.5 10.6 21.8 11.8 6.0 6.3 9.5 7.2 9.7 7.5 6.0 18.0 17.3 13.3 8.4 3.4 6.1 6.0 3.7 6.4 5.9 6.4 6.5 3.0 5.6 8.7 7.3 3.3 8.6 3.6 5.1 5.3 2.5 5.2 5.5 7.4 7.3 4.6 4.8 5.1 5.0 4.7 4.7 5.0 6.0 33.8 32.1 30.8 101.2 21.6 10.3 16.3 10.5 16.5 17.1 15.5 17.8 28.1 14.3 27.7 5.5 16.7 9.4 19.3 6.6 13.7 11.6 334.5 41.5 33.6 20.0 7.2 15.2 115.1 11.1 10.2 20.4 21.4 18.5 24.1 21.8 9.7 5.6 7.1 18.5 119.3 9.7 12.2 8.6 3.5 50.4 19.3 10.3 8.8 92.8 9.8 11.9 17.5 143.7 138.6 12.0 8.5 15.4 11.6 11.8 7.1 6.5 46.3 31.3 13.1 28.9 17.9 59.4 39.2 11.8 8.9 6.0 23.1 25.6 10.0 13.7 PIK3CD p110D ENSG00000171608 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta" O00329 1 9651731-9729114 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Chemotaxis, Differentiation, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 60.9;lymphoid tissue: 50.4" "Cell type enhanced" "Detected in many" "dendritic cells: 44.0;granulocytes: 25.3;Kupffer cells: 35.2;Microglial cells: 29.0;NK-cells: 29.9;T-cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 153.3;NB-4: 65.9;REH: 68.9;THP-1: 65.4;U-937: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015420, HPA044953" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Cytokinetic bridge" "CAB015420: AB_831654, HPA044953: AB_2679153" "unprognostic (5.73e-3)" "unprognostic (2.75e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-2)" "unprognostic (4.71e-2)" "unprognostic (1.40e-2)" "unprognostic (2.13e-1)" "unprognostic (7.42e-2)" "unprognostic (2.78e-2)" "unprognostic (1.54e-2)" "unprognostic (3.46e-2)" "unprognostic (6.75e-2)" "unprognostic (8.65e-3)" "unprognostic (2.09e-1)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (6.78e-2)" 7.2 3.1 6.8 33.4 6.3 60.9 3.9 6.1 7.5 6.2 6.4 5.4 5.2 4.9 1.7 4.9 6.1 7.0 3.3 7.0 5.3 6.4 3.5 12.0 46.9 7.3 6.6 7.0 3.0 2.9 2.8 4.2 7.8 4.6 3.4 0.6 5.1 2.7 1.2 3.0 17.2 4.7 6.6 50.4 5.7 4.0 9.3 24.3 5.5 3.5 32.0 7.4 5.1 8.5 8.1 5.2 0.4 1.4 1.3 1.1 0.7 12.1 24.5 26.0 21.1 0.3 3.3 21.5 4.9 9.8 12.4 2.4 2.0 11.0 16.2 153.3 0.4 2.4 1.3 9.0 5.1 56.0 18.7 4.3 4.5 29.2 9.8 11.4 3.8 14.9 8.0 0.1 15.0 0.6 5.4 65.9 2.2 0.3 1.4 68.9 13.0 0.7 10.9 0.0 1.7 1.5 2.7 4.9 11.9 6.8 0.8 65.4 9.8 7.7 7.9 0.2 11.5 4.9 4.9 30.1 16.7 78.6 4.4 18.0 23.5 40.2 21.6 23.0 22.6 12.8 16.3 19.9 22.5 13.6 20.9 23.1 63.2 25.9 29.2 25.7 13.3 38.3 6.8 6.3 6.1 7.5 7.0 5.3 7.3 6.6 7.8 6.6 9.3 8.5 1.7 9.6 13.4 2.0 22.2 1.5 2.2 1.8 4.0 0.7 2.0 1.7 3.1 0.0 1.1 0.0 2.1 0.3 44.0 0.1 1.9 3.9 3.0 2.0 1.7 2.7 0.0 10.3 6.7 2.0 0.5 2.9 0.0 1.0 25.3 4.2 3.6 0.0 14.7 0.0 13.4 0.1 0.0 35.2 6.0 2.8 1.2 23.1 3.6 29.0 19.3 2.5 29.9 1.0 1.1 11.3 0.0 1.5 8.2 4.1 0.2 3.8 3.3 1.3 6.6 2.0 4.7 1.5 3.4 2.9 1.1 0.3 37.1 1.5 0.2 2.1 PLPPR3 "FLJ11535, LPPR3, PRG-2, PRG2" ENSG00000129951 "Phospholipid phosphatase related 3" Q6T4P5 19 812488-821955 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 9.8;brain: 21.1;fallopian tube: 11.1" "Cell type enriched" "Detected in some" 7 "Endometrial ciliated cells: 37.2" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NB-4: 61.8;THP-1: 128.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052293, HPA057034" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA052293: AB_2681787, HPA057034: AB_2683316" "unprognostic (7.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.33e-2)" "unprognostic (3.66e-3)" "unprognostic (1.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.32e-1)" "unprognostic (4.51e-4)" "unprognostic (8.06e-3)" "unprognostic (1.07e-1)" "unprognostic (1.72e-12)" "unprognostic (1.21e-2)" "unprognostic (6.82e-2)" "unprognostic (8.50e-2)" "unprognostic (2.91e-1)" 0.0 0.0 16.8 0.2 14.1 9.8 2.2 0.0 21.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 11.1 0.1 0.1 14.2 11.5 0.0 0.0 2.3 0.1 4.1 8.2 0.3 0.0 0.2 0.4 0.0 1.5 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 2.3 0.2 0.1 3.2 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.5 12.2 0.0 0.0 0.0 6.9 0.2 0.1 0.0 0.0 0.7 0.1 0.1 8.4 0.1 0.1 0.3 2.3 0.0 0.0 0.0 5.2 0.0 1.6 0.0 0.5 4.4 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.1 12.0 0.3 0.0 1.1 0.0 61.8 9.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 15.5 0.3 0.0 0.0 6.3 5.4 128.9 0.1 0.2 0.2 0.3 0.1 0.2 0.5 0.2 0.0 10.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 14.1 0.0 21.1 14.2 11.5 4.1 8.2 1.5 2.3 13.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 3.7 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 37.2 0.6 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.4 0.0 1.2 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.9 0.1 5.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 PPCS FLJ11838 ENSG00000127125 "Phosphopantothenoylcysteine synthetase" Q9HAB8 1 42456117-42473385 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 397.2;Proximal tubular cells: 316.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031361, HPA031363" Approved Approved Mitochondria NA NA 17000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA031361: AB_10602150, HPA031363: AB_2673844" "unprognostic (1.49e-1)" "unprognostic (6.71e-2)" "unprognostic (8.15e-2)" "unprognostic (1.55e-1)" "unprognostic (3.84e-3)" "unprognostic (1.68e-2)" "prognostic unfavorable (5.96e-5)" "unprognostic (2.71e-1)" "unprognostic (7.79e-3)" "unprognostic (9.13e-3)" "unprognostic (3.24e-2)" "unprognostic (2.44e-1)" "unprognostic (2.41e-2)" "unprognostic (6.45e-2)" "unprognostic (2.32e-1)" "unprognostic (2.80e-1)" "unprognostic (4.30e-2)" 51.0 62.7 28.2 34.6 29.3 27.1 65.0 29.8 34.6 44.2 36.8 63.5 58.0 35.8 71.0 48.4 31.7 43.1 42.5 28.6 32.0 88.1 99.6 39.8 43.5 30.1 28.8 30.2 66.9 59.8 27.8 38.0 29.1 52.3 58.0 22.4 59.3 44.2 45.9 47.0 56.4 29.0 31.6 42.2 64.7 15.0 29.9 27.8 64.8 40.4 38.2 43.3 40.1 32.9 83.4 34.3 17.2 28.8 52.3 55.0 72.1 40.7 43.3 49.1 44.2 30.7 93.3 22.6 80.7 46.2 30.3 48.8 11.5 62.5 40.3 66.2 35.1 39.9 34.7 31.3 72.5 39.9 69.4 48.8 98.9 35.8 62.4 58.2 48.3 29.9 16.9 17.0 50.5 47.3 20.4 40.1 22.6 70.0 49.8 22.6 18.8 45.3 106.2 70.7 23.0 25.0 47.9 113.2 129.4 50.2 56.7 167.8 31.1 28.2 41.1 42.9 46.5 58.6 37.3 17.5 12.6 44.4 61.0 298.8 231.5 325.6 114.5 245.4 135.2 171.5 141.1 128.0 195.9 182.4 149.5 132.9 159.5 185.6 237.2 135.8 160.9 262.8 28.2 29.3 29.8 34.6 28.6 32.0 30.1 28.8 29.1 31.6 29.9 32.9 61.0 57.7 84.1 5.9 62.6 23.3 42.3 99.4 42.7 12.1 91.3 100.2 104.3 84.4 90.8 64.4 6.2 172.2 52.6 129.2 397.2 96.5 3.5 66.7 43.9 48.7 31.3 29.0 7.4 136.8 131.0 52.9 61.7 59.3 57.0 52.8 44.6 120.1 107.4 11.8 7.0 124.9 103.7 84.4 44.3 4.6 60.6 76.3 81.8 6.5 127.0 64.8 79.3 8.0 8.7 98.5 125.2 63.6 41.8 51.7 159.7 316.3 63.2 28.0 26.3 26.2 48.9 10.3 20.8 66.3 36.2 134.6 62.5 103.2 101.2 60.1 PPIAL4C ENSG00000263464 "Peptidylprolyl isomerase A like 4C" A0A0B4J2A2 1 149583865-149584464 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.4;lymphoid tissue: 2.2" "Cell type enriched" "Detected in single" 5 "Cardiomyocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 18.8;THP-1: 22.5" HPA058345 Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA058345: AB_2683685" "unprognostic (3.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (7.93e-2)" "unprognostic (5.98e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-1)" "unprognostic (6.61e-2)" "unprognostic (2.25e-1)" 0.3 1.9 0.5 2.2 0.5 0.2 0.4 0.7 0.9 0.4 0.4 0.8 3.4 0.9 0.0 0.1 0.1 0.1 0.0 0.5 0.5 0.7 0.3 1.0 2.1 0.5 0.5 0.2 0.0 0.2 0.2 0.8 0.5 0.4 0.2 0.0 0.0 0.1 0.5 0.3 1.8 0.1 0.4 1.7 0.8 0.0 0.5 0.0 0.1 0.0 0.8 0.1 0.1 0.5 4.1 0.0 0.5 3.2 0.2 0.5 2.8 0.5 0.2 1.2 0.9 0.0 6.4 1.9 2.4 0.0 3.1 4.5 0.0 0.3 0.8 4.8 0.0 0.4 0.0 0.0 0.1 1.1 1.7 0.2 1.0 0.8 0.4 0.0 0.0 0.2 0.9 6.1 0.9 0.7 7.4 18.8 7.6 0.8 0.1 7.2 0.1 12.2 0.0 0.0 5.0 6.8 0.8 13.1 7.9 0.0 6.1 22.5 0.0 4.4 6.1 3.2 10.5 4.4 6.9 11.9 5.0 5.8 9.8 1.6 3.8 1.6 4.1 5.2 4.8 7.0 4.6 4.5 8.0 6.2 3.8 5.0 0.3 3.3 3.6 8.3 6.1 12.0 0.5 0.5 0.7 0.9 0.5 0.5 0.5 0.5 0.5 0.4 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIAL4H ENSG00000270339 "Peptidylprolyl isomerase A like 4H" A0A075B767 1 146344131-146344790 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "THP-1: 1.2" HPA058345 Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "HPA058345: AB_2683685" "unprognostic (1.35e-1)" "unprognostic (2.13e-3)" "unprognostic (2.34e-1)" "unprognostic (2.76e-2)" "unprognostic (2.34e-1)" "unprognostic (2.84e-2)" 0.0 0.0 1.1 0.0 1.0 0.0 0.1 2.4 1.6 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.0 0.0 0.0 0.1 0.8 0.8 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 2.4 1.6 1.1 1.0 0.8 0.8 0.8 0.8 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIE "CyP-33, MGC111222, MGC3736" ENSG00000084072 "Peptidylprolyl isomerase E" Q9UNP9 1 39692182-39763914 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA019357, HPA020131" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA019357: AB_2670131, HPA020131: AB_1847405" "unprognostic (2.94e-1)" "unprognostic (4.32e-2)" "unprognostic (6.34e-2)" "unprognostic (6.97e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.52e-2)" "unprognostic (2.69e-1)" "unprognostic (3.88e-3)" "unprognostic (1.25e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (5.86e-2)" "unprognostic (3.95e-1)" "unprognostic (9.06e-2)" "unprognostic (1.00e-1)" 26.0 27.9 22.3 16.1 22.9 18.5 26.8 22.7 26.5 31.4 20.2 41.1 18.3 33.8 24.9 31.8 35.0 18.1 33.3 22.3 22.8 33.0 33.7 23.3 27.2 22.6 22.0 36.7 40.2 23.8 27.7 20.7 22.9 32.3 22.5 20.9 26.2 23.6 43.1 29.5 29.2 25.4 23.7 32.7 31.7 41.8 22.3 20.6 29.1 30.3 28.2 36.4 29.5 24.6 24.5 34.4 37.2 25.7 40.9 36.9 14.3 40.8 42.7 58.7 56.4 32.8 64.8 68.4 52.2 47.9 34.5 32.8 57.1 52.3 68.8 41.1 38.4 75.6 37.4 9.7 50.9 68.4 36.3 32.8 47.2 53.9 21.0 42.0 54.5 52.8 74.8 39.5 46.6 24.7 34.2 42.1 39.9 49.7 31.5 41.4 28.4 38.4 37.8 37.2 47.7 42.3 43.8 31.5 28.4 49.7 40.9 155.8 35.8 36.3 35.3 48.4 57.1 55.8 66.4 52.5 27.0 86.4 52.3 38.3 62.8 32.6 83.9 64.8 82.8 107.5 89.4 83.8 74.1 109.2 103.5 82.4 6.0 123.2 70.0 63.8 101.3 122.5 22.3 22.9 22.7 26.5 22.3 22.8 22.6 22.0 22.9 23.7 22.3 24.6 28.2 32.1 36.7 10.7 37.0 24.9 43.1 69.8 23.9 25.9 30.3 47.5 31.8 21.5 62.1 33.1 14.6 62.5 39.3 22.8 66.5 57.5 29.2 34.6 27.7 28.7 28.8 38.3 7.7 48.4 59.3 34.0 16.3 23.4 55.2 44.1 37.9 31.1 56.1 23.5 8.8 32.9 40.7 33.4 26.9 76.3 29.8 30.0 39.2 8.4 46.8 34.0 58.7 8.0 13.6 40.0 24.1 45.1 31.7 32.0 39.3 69.8 63.4 29.7 59.2 23.3 40.1 76.1 51.4 24.5 26.3 34.8 36.6 36.3 35.9 32.9 PPIH "CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP" ENSG00000171960 "Peptidylprolyl isomerase H" O43447 1 42658335-42676758 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059019 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "HPA059019: AB_2683885" "unprognostic (7.93e-3)" "unprognostic (5.49e-3)" "unprognostic (2.53e-2)" "unprognostic (6.42e-2)" "unprognostic (3.79e-2)" "unprognostic (1.95e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (1.09e-1)" "unprognostic (2.37e-2)" "unprognostic (1.82e-2)" "unprognostic (2.84e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.78e-9)" "unprognostic (6.59e-3)" "unprognostic (4.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" 22.9 23.2 22.1 27.8 23.1 56.8 27.7 23.7 29.5 24.8 20.8 33.2 24.4 23.5 25.4 36.4 23.5 17.9 25.8 23.0 22.5 22.1 17.5 22.4 44.5 22.2 22.0 25.8 19.2 18.3 13.4 24.7 22.7 21.2 32.8 22.4 23.9 18.3 19.8 27.5 27.8 21.5 21.8 32.3 23.4 22.9 22.5 60.3 26.0 21.1 50.4 26.6 25.8 23.3 105.8 66.4 80.1 113.3 24.9 51.5 101.4 67.6 50.1 127.4 114.4 98.1 111.8 171.5 85.9 52.8 61.7 82.3 150.8 108.2 133.9 150.2 119.7 156.4 104.4 98.6 21.4 322.0 90.7 31.2 57.5 117.9 90.6 49.1 60.6 161.2 205.7 91.7 63.8 84.2 250.1 451.0 200.4 100.4 77.7 136.8 150.2 152.2 64.1 64.8 59.2 113.5 59.6 101.1 77.4 100.8 54.5 465.0 48.1 53.2 143.1 77.0 171.7 60.0 140.2 319.6 62.8 294.9 94.8 29.7 15.1 33.3 35.0 23.5 33.3 33.6 35.7 39.9 20.7 32.9 36.1 43.5 3.6 36.4 21.8 25.9 38.2 25.0 22.1 23.1 23.7 29.5 23.0 22.5 22.2 22.0 22.7 21.8 22.5 23.3 31.3 19.2 20.7 9.8 48.1 28.9 48.2 51.7 38.7 10.0 30.1 44.4 14.1 11.5 25.8 22.0 4.2 62.5 37.7 15.7 45.0 29.4 33.2 23.4 27.4 25.1 21.5 49.8 12.7 26.4 104.5 25.5 27.5 21.6 31.0 46.9 19.2 11.2 52.1 5.0 9.6 27.3 34.6 18.6 25.6 7.3 29.2 28.5 16.0 9.4 26.2 22.2 52.5 11.6 11.6 25.8 17.6 21.4 45.6 28.0 16.1 34.1 19.6 16.1 19.7 21.5 42.0 19.7 32.3 54.6 21.5 37.9 42.7 46.4 40.0 38.7 PPP1R27 "DYSFIP1, toonin" ENSG00000182676 "Protein phosphatase 1 regulatory subunit 27" Q86WC6 17 81833492-81835050 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skeletal muscle: 1205.9" "Group enriched" "Detected in some" 14 "Early spermatids: 56.5;Skeletal myocytes: 108.8" "Cancer enriched" "Detected in single" 10 "head and neck cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "HL-60: 206.4;THP-1: 385.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042227, HPA048632" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA042227: , HPA048632: AB_2680469" "unprognostic (3.35e-2)" "unprognostic (1.12e-4)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (1.29e-1)" "unprognostic (1.85e-2)" "unprognostic (1.37e-1)" "unprognostic (2.21e-2)" "unprognostic (7.07e-2)" "unprognostic (1.32e-1)" "unprognostic (5.38e-2)" "unprognostic (8.70e-2)" "unprognostic (4.98e-6)" "unprognostic (7.97e-2)" "unprognostic (1.21e-1)" "unprognostic (2.19e-3)" "unprognostic (1.30e-1)" 0.3 0.9 0.0 0.0 0.1 1.3 0.4 0.2 0.3 0.4 0.0 0.2 0.0 0.1 0.0 1.2 0.1 0.0 0.5 0.1 0.0 0.2 0.7 0.2 0.0 0.1 0.0 0.2 0.4 0.0 11.8 0.0 0.1 1.8 0.0 0.0 5.8 0.0 1205.9 2.1 0.2 0.0 0.0 0.2 0.1 0.5 0.1 0.1 0.4 47.6 0.0 0.1 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 206.4 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 1.4 0.2 0.0 0.0 385.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 1.3 0.0 0.0 0.0 0.3 0.0 0.3 0.1 1.2 2.9 1.3 2.4 0.6 0.0 0.2 0.0 0.0 3.0 0.3 1.6 0.0 0.0 56.5 0.9 0.7 0.9 1.2 0.0 0.0 0.5 2.7 0.6 0.0 1.5 0.0 0.7 1.1 1.2 0.6 0.0 0.0 1.1 0.0 0.0 0.4 5.7 0.9 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.4 0.0 0.3 4.7 0.2 0.2 0.2 0.0 108.8 0.5 1.7 0.6 1.2 0.1 1.4 0.2 0.2 1.6 0.5 PPP1R3A "GM, PPP1R3" ENSG00000154415 "Protein phosphatase 1 regulatory subunit 3A" Q16821 7 113876777-114075920 "Disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 64 "heart muscle: 40.8;skeletal muscle: 152.9;tongue: 104.1" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 157.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 67 "THP-1: 14.6" "Region enriched" "Detected in single" 12 "thalamus: 1.1" "Not detected" "Not detected" "HPA070440, HPA073138" Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA070440: , HPA073138: " "unprognostic (8.96e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 40.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.0 0.0 152.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 104.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.8 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPP1R3G ENSG00000219607 "Protein phosphatase 1 regulatory subunit 3G" B7ZBB8 6 5085341-5089487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 5.9;liver: 6.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 18.5;Glandular and luminal cells: 7.2" "Cancer enhanced" "Detected in many" "liver cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.3;PC-3: 3.9;THP-1: 14.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056393 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA056393: AB_2683115" "unprognostic (1.99e-2)" "unprognostic (5.50e-3)" "unprognostic (2.10e-1)" "unprognostic (5.29e-2)" "unprognostic (1.70e-2)" "unprognostic (1.38e-1)" "unprognostic (6.56e-3)" "unprognostic (8.64e-3)" "unprognostic (1.81e-2)" "unprognostic (2.98e-1)" "unprognostic (1.04e-2)" "unprognostic (3.71e-1)" "unprognostic (7.60e-2)" "unprognostic (1.33e-2)" "unprognostic (5.56e-2)" "unprognostic (3.17e-3)" "unprognostic (1.27e-1)" 2.3 3.0 2.3 0.3 2.1 0.1 1.4 1.5 2.7 2.1 0.9 2.0 0.2 1.2 1.0 1.8 1.0 0.3 5.9 2.0 1.8 0.6 6.2 0.3 0.5 2.3 2.3 0.8 0.1 0.3 0.2 0.7 1.9 1.2 0.5 0.2 0.6 1.4 0.5 1.2 0.5 0.5 1.6 2.8 0.6 0.2 2.2 0.2 0.3 0.2 0.4 2.8 2.1 1.7 0.0 0.2 0.1 0.0 1.6 1.0 0.0 0.3 0.4 0.2 0.3 0.0 0.3 0.0 3.3 0.6 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.3 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 3.9 0.1 0.0 0.0 0.4 0.4 0.0 0.0 0.5 0.0 0.0 0.3 0.0 14.6 0.0 0.0 0.0 0.8 0.5 2.0 1.7 0.0 0.6 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 2.3 2.1 1.5 2.7 2.0 1.8 2.3 2.3 1.9 1.6 2.2 1.7 4.2 0.0 0.0 0.0 0.4 0.5 0.5 0.4 0.0 0.5 0.2 0.1 18.5 0.0 0.1 3.7 0.0 0.8 0.0 1.3 0.0 0.3 0.0 1.2 2.0 1.9 1.2 0.0 0.0 0.0 0.4 3.7 0.0 7.2 0.0 1.4 2.9 0.0 4.5 0.0 0.0 0.9 0.0 4.0 4.7 0.2 0.9 1.8 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.6 1.8 3.0 1.8 0.4 0.0 2.1 0.2 0.2 0.0 2.0 2.5 0.1 0.9 0.2 0.3 0.8 0.2 0.5 1.4 1.2 PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40072710-40097260 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 251.9;Kupffer cells: 315.8;Langerhans cells: 328.8;Macrophages: 271.3;monocytes: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 1254.3;eosinophil: 624.2;intermediate monocyte: 1006.3;myeloid DC: 1091.1;neutrophil: 683.9;non-classical monocyte: 815.7" "Group enriched" "Detected in all" 4 "dendritic cells: 1091.1;granulocytes: 683.9;monocytes: 1254.3" "Cell line enhanced" "Detected in all" "SK-BR-3: 1082.7;THP-1: 1449.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 240000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" 69.8 59.4 92.9 92.7 95.6 117.5 95.7 100.4 135.9 70.1 106.1 50.5 32.1 72.7 60.1 45.1 55.4 57.1 45.3 93.6 101.2 75.8 54.1 128.5 93.9 97.0 96.7 68.6 42.6 79.2 39.0 74.8 99.6 73.4 58.8 89.4 56.8 63.2 21.3 40.3 39.2 95.3 101.6 177.0 45.1 37.6 99.1 78.0 60.0 37.1 75.1 79.1 34.7 113.5 115.6 62.5 93.7 81.0 106.5 92.1 209.8 68.4 127.9 153.0 183.3 350.1 270.5 140.1 118.1 65.2 112.2 209.5 154.9 112.7 163.6 186.4 151.4 100.3 127.2 155.5 137.5 233.7 158.9 103.1 107.5 108.7 126.4 79.7 190.9 108.8 167.7 247.0 80.6 168.1 109.8 88.3 258.3 163.9 93.8 116.0 263.7 226.1 89.2 152.0 114.1 96.9 247.9 1082.7 298.6 111.7 199.3 1449.6 85.2 100.7 147.1 70.7 174.9 161.2 383.8 133.9 109.4 408.7 155.5 85.7 1254.3 624.2 122.2 1006.3 137.9 118.8 171.5 131.3 1091.1 118.6 227.0 168.3 683.9 100.3 815.7 101.8 204.1 1586.9 92.9 95.6 100.4 135.9 93.6 101.2 97.0 96.7 99.6 101.6 99.1 113.5 45.2 28.9 47.7 19.9 33.3 39.6 77.1 30.8 34.7 46.6 55.3 37.5 15.7 41.5 40.0 38.6 16.7 51.7 28.9 4.7 5.9 59.0 64.8 13.8 46.4 49.6 19.9 40.1 28.4 42.1 66.5 56.6 14.8 18.2 84.9 34.6 47.5 9.3 251.9 25.2 39.2 8.1 20.3 315.8 328.8 87.6 31.4 271.3 67.6 31.9 227.2 120.3 28.8 27.6 22.7 22.2 6.0 39.5 34.2 42.4 3.2 18.5 32.3 37.0 19.7 30.5 49.3 17.5 33.0 19.1 27.3 41.2 43.5 39.4 11.4 35.6 PRPF3 "hPrp3, Prp3, RP18, SNRNP90" ENSG00000117360 "Pre-mRNA processing factor 3" O43395 1 150321479-150353233 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027226, HPA067116" Approved Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA027226: AB_1855770, HPA067116: AB_2685783" "unprognostic (2.75e-1)" "unprognostic (3.00e-1)" "unprognostic (2.20e-1)" "unprognostic (2.77e-1)" "unprognostic (1.78e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.59e-5)" "unprognostic (7.89e-2)" "unprognostic (7.13e-3)" "unprognostic (1.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (3.19e-5)" "unprognostic (6.77e-3)" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "unprognostic (7.78e-3)" 26.0 24.7 18.1 22.3 20.2 44.8 27.0 23.2 23.1 27.5 22.8 25.2 16.9 25.0 26.7 22.2 25.7 13.8 19.5 17.8 21.4 29.0 30.4 24.3 28.6 19.7 18.9 34.1 23.8 17.6 27.0 20.9 19.3 27.5 19.6 43.5 21.7 19.5 22.2 23.8 24.6 18.7 17.3 33.8 19.1 20.1 19.7 30.9 32.0 14.9 28.5 24.3 24.3 21.6 44.8 47.5 47.1 30.3 31.0 33.5 63.8 45.6 31.9 69.1 47.5 36.6 40.8 58.7 29.7 37.6 64.4 51.5 86.1 32.2 61.7 29.7 38.3 50.7 72.1 35.2 30.7 62.5 31.6 24.6 43.7 59.0 50.5 32.9 42.7 39.0 61.3 34.8 50.0 66.5 52.3 55.0 67.6 114.3 41.9 75.1 38.5 38.8 28.5 26.7 40.3 35.7 37.9 44.2 34.9 63.3 52.9 150.5 34.3 43.2 33.3 36.7 75.8 33.1 62.8 64.7 28.8 56.2 45.9 9.3 9.0 13.3 14.9 11.8 14.6 13.0 10.8 9.8 9.5 10.0 11.0 11.4 5.3 11.5 21.8 7.6 9.1 8.3 18.1 20.2 23.2 23.1 17.8 21.4 19.7 18.9 19.3 17.3 19.7 21.6 26.1 35.3 23.4 31.6 26.1 11.7 13.1 13.0 10.8 30.4 10.8 10.8 13.2 11.5 19.7 11.0 18.8 16.1 22.9 15.8 13.7 15.6 11.5 13.2 20.0 22.5 2.4 19.0 19.5 11.9 16.0 16.3 17.9 17.8 22.8 25.5 14.6 11.0 12.1 32.0 17.5 17.5 4.1 8.6 11.8 5.3 20.2 14.5 10.6 15.0 14.2 27.8 17.5 18.1 28.4 13.4 9.5 18.4 12.4 12.6 12.6 5.0 20.6 42.6 13.1 19.1 21.2 44.3 23.5 11.6 10.1 20.0 24.0 11.3 11.6 10.0 PRTN3 "ACPA, AGP7, C-ANCA, MBT, P29, PR-3" ENSG00000196415 "Proteinase 3" P24158 19 840999-848175 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "bone marrow: 2098.1" "Cell type enriched" "Detected in some" 17 "Erythroid cells: 26.5" "Cancer enhanced" "Detected in single" "stomach cancer: 1.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 8 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.0" "Cell line enriched" "Detected in some" 6 "THP-1: 2054.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005938, CAB017558" Enhanced Approved Vesicles,Cytosol "Secreted to blood" NA NA 390000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Vesicles "CAB017558: AB_2172317, HPA005938: AB_1855764" "unprognostic (2.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.83e-3)" "unprognostic (4.20e-1)" "unprognostic (3.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.98e-3)" "unprognostic (3.67e-2)" "unprognostic (8.62e-6)" "unprognostic (5.31e-2)" "unprognostic (2.00e-1)" "unprognostic (5.14e-2)" 0.8 0.2 0.6 0.0 0.7 2098.1 0.4 0.2 1.3 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.0 1.6 0.6 0.4 0.3 2.8 11.7 0.4 0.3 0.4 0.1 0.1 0.2 1.3 0.6 0.4 0.3 0.0 0.0 1.6 0.0 0.3 1.3 0.0 0.0 0.2 38.2 0.1 0.2 0.6 7.1 0.4 0.0 0.0 0.0 0.1 0.4 1.2 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 343.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 2054.4 0.0 0.0 0.0 0.2 0.9 0.0 0.2 0.3 0.0 14.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 9.9 0.6 0.7 0.2 1.3 0.6 0.4 0.3 0.4 0.4 0.2 0.6 0.4 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.8 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 26.5 0.4 0.0 0.9 0.9 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 1.5 0.0 0.1 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.1 PSD2 "DKFZp761B0514, EFA6C" ENSG00000146005 "Pleckstrin and Sec7 domain containing 2" Q9BQI7 5 139795808-139844466 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 106.3" "Cell type enriched" "Detected in some" 4 "Astrocytes: 229.9" "Cancer enriched" "Detected in single" 43 "glioma: 19.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "THP-1: 1.1;U-2 OS: 1.1;U-698: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054625 Approved "Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA054625: " "unprognostic (3.76e-2)" "unprognostic (1.90e-1)" "unprognostic (1.34e-3)" "unprognostic (2.48e-3)" "unprognostic (1.34e-2)" "unprognostic (5.01e-2)" "unprognostic (1.22e-2)" "unprognostic (6.55e-2)" "unprognostic (2.42e-1)" "unprognostic (2.17e-1)" "unprognostic (2.53e-1)" "unprognostic (4.02e-1)" "unprognostic (4.16e-3)" "unprognostic (3.40e-2)" "unprognostic (2.28e-1)" "unprognostic (3.07e-1)" "unprognostic (2.12e-3)" 0.1 0.3 70.8 0.3 91.3 0.2 0.5 86.5 63.1 0.8 22.0 0.2 0.1 0.2 1.6 0.0 0.4 0.2 0.2 58.7 76.3 0.1 0.1 0.1 0.0 90.6 106.2 0.1 0.4 0.0 0.9 0.0 79.2 0.2 0.1 4.1 1.7 0.4 0.3 0.1 0.1 0.1 70.5 0.2 0.1 1.1 106.3 1.0 0.1 0.0 0.1 0.1 0.2 56.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.5 0.9 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.3 1.1 0.0 0.0 0.2 0.0 1.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.8 91.3 86.5 63.1 58.7 76.3 90.6 106.2 79.2 70.5 106.3 56.3 0.0 0.0 0.0 229.9 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 9.1 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 6.5 0.0 2.6 0.0 52.8 24.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.6 0.0 1.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTGES3L ENSG00000267060 "Prostaglandin E synthase 3 like" 17 42968088-42980433 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "heart muscle: 41.4;skeletal muscle: 124.3;tongue: 95.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 45.6;Cone photoreceptor cells: 8.4;Early spermatids: 13.1;Spermatocytes: 8.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 4.1" "Lineage enriched" "Detected in single" 5 "dendritic cells: 4.1" "Cell line enhanced" "Detected in many" "THP-1: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" "unprognostic (9.77e-2)" "unprognostic (6.61e-2)" "unprognostic (7.45e-2)" "unprognostic (4.66e-2)" "unprognostic (2.36e-2)" "unprognostic (1.31e-2)" "unprognostic (1.24e-1)" "unprognostic (6.23e-2)" "unprognostic (2.80e-4)" "unprognostic (9.24e-2)" "unprognostic (3.03e-2)" "unprognostic (1.40e-1)" "unprognostic (3.10e-1)" "unprognostic (6.25e-2)" "unprognostic (4.08e-2)" 0.9 0.6 1.9 1.4 3.1 3.0 1.1 2.1 2.8 1.5 1.8 13.2 1.4 8.2 1.4 3.4 2.5 1.6 41.4 1.9 1.5 0.6 0.3 0.7 1.1 1.6 1.5 0.6 0.5 0.4 1.3 0.5 1.8 2.9 2.8 1.7 2.4 3.4 124.3 1.0 2.5 7.2 1.1 0.7 3.4 2.2 1.5 0.6 0.8 95.1 0.9 5.7 1.2 2.4 0.8 0.6 1.9 2.8 0.1 0.3 1.6 1.2 0.5 1.0 0.6 1.7 0.7 0.7 0.5 0.5 1.0 1.6 1.4 1.5 1.9 0.5 0.7 4.3 3.1 3.1 0.1 0.8 7.1 0.5 1.1 2.2 1.8 0.7 0.3 3.1 1.8 1.4 2.1 0.7 2.8 2.1 1.8 2.2 0.6 1.4 6.3 0.7 1.7 1.5 1.5 4.9 1.3 3.4 2.0 2.2 1.9 16.7 0.4 2.0 1.8 0.6 1.2 3.0 2.1 0.8 0.3 1.0 0.7 0.9 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.5 0.3 0.1 4.1 0.1 0.4 1.9 3.1 2.1 2.8 1.9 1.5 1.6 1.5 1.8 1.1 1.5 2.4 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.8 1.5 1.3 45.6 0.0 0.1 0.0 8.4 0.1 2.9 1.4 0.0 1.4 13.1 1.2 0.4 1.0 1.8 0.0 0.0 0.2 0.6 2.4 0.0 1.1 0.0 0.8 0.7 0.1 1.1 0.0 0.0 0.9 0.0 0.6 0.7 4.5 0.6 2.1 0.0 0.0 1.7 0.8 1.0 0.0 0.0 0.7 2.8 0.4 0.0 0.7 1.1 0.5 0.9 2.6 0.0 2.7 2.5 8.2 3.4 0.0 0.0 0.1 0.2 4.8 1.1 0.3 PTGES3L-AARSD1 ENSG00000108825 "PTGES3L-AARSD1 readthrough" Q9BTE6 17 42950526-42980528 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 17.3;tongue: 10.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.5;granulocytes: 3.8;Respiratory ciliated cells: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 16 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 16 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "RH-30: 4.9;THP-1: 10.8" "HPA021408, HPA022869, HPA023714" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Nuclear membrane, Cytosol" "HPA021408: AB_1844410, HPA022869: AB_1844411, HPA023714: AB_1844412" "unprognostic (6.47e-2)" "unprognostic (1.25e-1)" "unprognostic (2.87e-1)" "unprognostic (5.44e-2)" "unprognostic (9.34e-4)" "unprognostic (1.56e-1)" "unprognostic (2.27e-3)" "unprognostic (2.23e-1)" "unprognostic (1.41e-1)" "unprognostic (1.33e-1)" "unprognostic (1.18e-2)" "unprognostic (1.17e-2)" "unprognostic (1.82e-1)" "unprognostic (5.13e-1)" "unprognostic (3.27e-2)" "unprognostic (1.91e-4)" "unprognostic (1.83e-1)" 0.4 0.2 0.1 0.8 1.0 0.7 0.4 0.0 0.8 0.7 0.2 4.3 0.8 3.2 0.4 1.1 1.0 0.8 3.0 0.3 0.3 0.3 0.2 0.4 0.2 0.1 0.1 0.3 0.3 0.3 1.2 0.2 0.0 1.3 1.8 0.6 0.6 1.7 17.3 0.3 1.2 5.6 0.0 0.2 1.5 3.3 0.0 0.2 0.3 10.6 0.2 1.9 0.6 0.3 0.6 0.0 1.7 1.8 0.1 0.0 0.4 1.2 1.5 0.8 0.7 1.2 0.1 0.1 1.2 0.2 0.5 0.0 0.3 0.8 1.2 0.7 0.2 4.1 1.7 2.5 0.0 0.5 2.7 0.0 0.5 1.3 0.0 0.5 0.3 1.1 1.3 0.3 1.6 0.0 1.4 0.4 0.4 2.5 0.4 0.7 4.9 0.5 0.2 0.3 0.8 2.4 1.0 0.3 1.1 2.3 0.5 10.8 0.0 0.5 0.9 0.0 0.4 2.9 0.8 0.2 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 1.0 0.0 0.8 0.3 0.3 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 PTPN9 MEG2 ENSG00000169410 "Protein tyrosine phosphatase non-receptor type 9" P43378 15 75463251-75579315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 63.0;Excitatory neurons: 66.1;Inhibitory neurons: 63.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041922 Approved Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA041922: AB_10795269" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (2.42e-1)" "unprognostic (1.54e-2)" "unprognostic (6.80e-2)" "unprognostic (7.38e-2)" "unprognostic (5.95e-2)" "unprognostic (3.93e-1)" "unprognostic (3.14e-1)" "unprognostic (9.25e-3)" "unprognostic (6.35e-2)" "prognostic favorable (2.49e-6)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.39e-1)" 15.9 12.0 14.8 13.0 16.3 10.8 15.1 11.9 18.8 16.6 11.7 18.0 17.9 16.5 13.3 9.9 16.2 12.1 11.0 16.9 18.4 18.2 14.7 15.8 14.5 18.6 14.4 14.0 10.2 17.9 9.7 19.9 15.1 16.6 19.7 8.9 13.0 21.2 6.4 11.0 20.0 18.0 13.6 13.4 13.5 7.2 17.0 16.1 32.8 13.1 15.0 18.1 13.8 14.5 20.3 24.1 36.7 24.6 26.8 29.3 12.0 29.8 46.2 36.9 33.4 14.5 30.0 32.6 23.3 51.1 29.5 30.0 79.9 34.3 37.0 40.5 19.8 18.4 16.2 15.7 40.2 28.2 27.1 38.4 35.2 29.6 45.9 37.7 31.4 21.3 12.4 11.5 42.1 13.5 20.0 26.3 33.6 18.2 12.1 38.9 18.2 9.1 46.6 32.5 14.4 29.9 42.4 23.3 46.3 34.9 12.1 47.8 36.5 35.2 11.3 23.3 32.2 16.9 18.9 30.0 20.5 41.9 35.3 3.2 2.2 2.3 3.4 3.0 2.8 1.7 2.4 3.0 3.0 1.3 1.0 1.8 0.3 3.9 2.9 2.0 1.6 1.7 14.8 16.3 11.9 18.8 16.9 18.4 18.6 14.4 15.1 13.6 17.0 14.5 12.7 6.4 13.4 63.0 9.2 3.3 8.2 6.6 5.7 12.1 8.0 7.1 3.7 10.0 8.1 11.0 8.4 20.0 7.3 25.0 15.6 10.8 3.0 7.9 19.4 10.0 7.2 13.7 66.1 9.9 4.2 20.6 10.7 11.4 15.2 23.6 17.5 12.6 18.8 3.3 63.2 11.5 6.1 18.9 18.1 4.7 12.5 16.5 7.2 46.9 24.2 5.6 19.6 48.7 19.6 18.2 12.6 27.4 9.7 12.1 24.9 14.0 8.1 17.1 13.1 11.7 20.8 10.6 9.4 6.6 3.3 10.1 13.4 11.6 13.2 13.1 PYM1 "PYM, WIBG" ENSG00000170473 "PYM homolog 1, exon junction complex associated factor" Q9BRP8 12 55901413-55932618 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012803, HPA039717, HPA046200" Supported Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" No No 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "Cell Junctions" "CAB012803: AB_2269494, HPA039717: AB_2676644, HPA046200: AB_10965556" "unprognostic (3.03e-2)" "unprognostic (1.00e-1)" "unprognostic (5.65e-2)" "unprognostic (8.82e-2)" "unprognostic (1.97e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.44e-2)" "unprognostic (3.94e-2)" "unprognostic (1.29e-1)" "unprognostic (1.32e-2)" "unprognostic (1.59e-2)" "unprognostic (2.22e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.34e-4)" 24.5 30.8 19.8 24.0 20.2 22.5 27.9 21.5 24.8 26.1 22.9 31.1 31.6 22.1 41.5 72.3 22.7 19.8 21.8 19.5 20.7 26.3 43.0 20.8 35.4 20.5 20.6 17.1 28.0 26.3 22.3 22.8 20.5 31.2 30.0 17.4 34.0 15.9 29.8 41.9 29.5 19.8 20.1 31.1 24.1 25.9 20.1 33.2 27.0 29.0 42.1 24.8 31.4 20.2 50.3 39.1 56.1 31.4 33.4 43.2 92.6 36.1 43.1 33.3 28.0 57.7 57.9 62.9 53.6 35.1 15.4 38.6 43.6 77.1 26.7 48.6 32.7 51.0 35.1 71.8 40.7 59.7 44.7 39.2 48.8 37.7 56.0 42.2 35.9 27.3 44.5 67.4 39.7 75.3 38.6 105.7 98.3 56.7 20.2 34.3 22.3 72.5 69.5 69.8 37.7 43.4 46.2 61.1 33.1 51.8 74.5 124.0 28.2 20.0 28.3 31.5 26.6 35.5 58.2 97.2 34.2 40.9 31.9 17.5 79.8 75.8 58.5 92.2 72.3 98.1 105.4 82.2 120.2 88.2 68.7 69.5 19.1 53.1 66.5 65.6 186.0 87.2 19.8 20.2 21.5 24.8 19.5 20.7 20.5 20.6 20.5 20.1 20.1 20.2 16.2 19.2 17.3 0.0 28.6 0.0 29.4 0.0 21.1 12.7 41.7 38.4 0.0 25.8 14.2 23.9 8.4 84.3 21.1 29.8 78.2 40.6 15.2 21.1 17.0 16.3 7.3 32.2 0.0 50.6 76.3 17.6 22.4 21.1 18.9 14.5 22.9 44.3 55.2 6.7 0.0 32.1 0.0 47.7 0.0 11.7 23.3 42.8 0.0 0.0 110.4 55.7 48.4 0.0 0.0 54.1 33.7 23.7 21.9 34.7 66.8 61.3 16.8 13.6 13.1 18.0 15.7 23.8 25.6 63.1 0.0 62.0 29.6 16.5 29.3 34.3 RAB40C "RARL, RASL8C" ENSG00000197562 "RAB40C, member RAS oncogene family" Q96S21 16 589357-629272 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 58.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 14.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 14.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076172 Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 50: Non-specific - Ribosome" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA076172: " "unprognostic (8.04e-2)" "unprognostic (3.63e-1)" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (5.38e-3)" "unprognostic (1.07e-2)" "prognostic unfavorable (1.18e-4)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (5.78e-2)" "unprognostic (3.45e-2)" "unprognostic (2.90e-1)" "unprognostic (1.37e-3)" "unprognostic (3.89e-2)" "unprognostic (6.20e-2)" "unprognostic (7.48e-2)" "unprognostic (4.00e-3)" 10.5 8.0 7.4 4.5 10.0 5.8 11.6 7.1 17.7 13.2 0.0 20.3 13.3 13.0 5.1 20.4 12.2 4.5 12.5 10.9 2.0 13.9 12.8 13.3 4.1 3.4 2.6 12.1 38.5 5.1 21.4 6.6 3.2 17.5 4.4 1.9 14.3 5.9 18.8 58.0 13.6 4.4 1.5 7.9 19.3 13.8 4.0 10.2 10.6 6.2 2.6 18.3 16.1 8.8 7.7 16.3 9.4 13.2 5.3 6.6 12.6 10.1 4.7 8.0 6.5 14.7 13.7 8.8 10.5 6.0 7.1 17.1 5.8 8.3 1.6 9.3 9.8 4.9 11.3 10.5 9.4 9.9 8.9 5.6 17.9 6.4 6.7 5.6 6.6 10.3 11.2 8.8 3.5 22.7 9.6 18.0 10.9 13.5 9.4 15.4 6.7 14.1 4.7 10.9 12.8 10.3 11.1 24.1 9.4 4.3 17.8 19.6 8.2 8.4 11.8 11.3 6.1 8.4 8.6 11.0 5.5 13.4 8.9 1.1 2.8 14.0 0.4 1.8 1.9 1.1 1.4 1.5 1.6 0.7 1.0 0.7 4.8 0.8 0.8 0.7 0.6 1.3 7.4 10.0 7.1 17.7 10.9 2.0 3.4 2.6 3.2 1.5 4.0 8.8 7.1 9.6 15.7 20.5 4.3 17.5 9.9 11.3 18.2 11.4 9.8 7.9 6.3 8.6 10.4 11.0 8.4 26.6 7.7 33.2 7.9 6.2 4.0 12.1 7.1 5.4 10.8 5.2 44.5 12.5 15.3 4.7 23.4 12.7 7.0 11.2 7.5 16.2 9.4 16.8 18.6 16.5 24.4 6.1 4.1 6.6 5.0 4.5 7.2 10.3 7.5 8.4 7.2 10.6 14.8 10.4 21.3 6.4 2.5 10.8 38.2 9.7 11.2 3.3 0.0 5.6 5.8 17.1 13.9 24.8 31.1 56.8 4.6 7.2 18.7 8.6 RIMBP3 "KIAA1666, RIMBP3.1, RIMBP3A" ENSG00000275793 "RIMS binding protein 3" Q9UFD9 22 18605815-18611919 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 27 "brain: 35.7;choroid plexus: 24.5;testis: 28.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MOLT-4: 3.0;THP-1: 3.2" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (1.55e-2)" "unprognostic (3.95e-3)" "unprognostic (1.62e-1)" "unprognostic (3.95e-2)" "unprognostic (2.29e-2)" "unprognostic (9.81e-3)" "unprognostic (1.83e-3)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (4.72e-3)" "unprognostic (6.06e-3)" "unprognostic (9.58e-2)" "unprognostic (8.49e-3)" "unprognostic (7.23e-2)" "unprognostic (1.03e-1)" "unprognostic (2.69e-3)" "unprognostic (7.95e-2)" 0.1 0.2 7.9 0.4 10.8 0.1 0.0 35.7 22.0 0.1 24.5 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 11.0 11.7 0.0 0.0 0.2 0.8 14.9 10.1 0.1 0.1 0.3 0.1 0.2 26.2 0.2 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.0 19.6 0.7 0.2 28.4 13.5 1.0 0.4 0.0 0.5 0.0 0.0 32.4 0.4 1.3 0.5 0.4 0.7 0.3 0.0 0.5 1.4 0.6 0.7 0.0 0.0 0.3 0.6 0.2 0.4 0.3 0.3 0.0 0.1 1.4 0.4 0.6 0.3 0.5 0.0 2.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 1.1 0.2 0.3 0.5 0.6 3.0 1.7 0.6 0.6 0.1 1.2 1.6 0.2 0.1 0.1 0.8 0.1 1.2 0.0 0.2 0.1 0.1 3.2 0.1 1.0 0.7 0.5 0.3 0.0 0.4 0.3 0.5 0.7 1.1 0.0 0.2 0.2 0.1 0.1 0.4 0.1 0.2 0.2 0.2 0.1 0.3 0.2 0.1 0.3 0.0 0.0 0.2 0.3 7.9 10.8 35.7 22.0 11.0 11.7 14.9 10.1 26.2 19.6 13.5 32.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RIMBP3B ENSG00000274600 "RIMS binding protein 3B" A6NNM3 22 21383374-21389478 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 49 "brain: 41.3;choroid plexus: 18.4;testis: 13.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.2;RH-30: 1.1;THP-1: 2.1" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (3.78e-1)" "unprognostic (3.54e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.28e-1)" "unprognostic (5.35e-2)" "unprognostic (4.37e-1)" "unprognostic (3.61e-4)" "unprognostic (1.69e-2)" "unprognostic (7.11e-2)" 0.0 0.1 8.2 0.4 12.8 0.0 0.0 41.3 19.1 0.0 18.4 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 10.4 13.6 0.0 0.0 0.1 0.3 16.5 12.6 0.0 0.1 0.2 0.0 0.2 19.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 16.2 0.2 0.0 13.6 13.2 0.4 0.1 0.0 0.2 0.0 0.0 29.6 0.0 0.5 0.1 0.1 0.3 0.2 0.1 0.1 0.4 0.2 0.2 0.0 0.1 0.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.2 0.2 0.9 1.2 0.1 0.2 0.1 0.8 1.1 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.2 0.6 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.2 0.1 0.0 0.2 0.1 8.2 12.8 41.3 19.1 10.4 13.6 16.5 12.6 19.2 16.2 13.2 29.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RLF "Zn-15L, ZNF292L" ENSG00000117000 "RLF zinc finger" Q13129 1 40161387-40240921 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054653, HPA057300" Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 42: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Nucleoli "HPA054653: AB_2682557, HPA057300: AB_2683404" "unprognostic (1.71e-1)" "unprognostic (2.24e-2)" "unprognostic (6.46e-2)" "unprognostic (1.88e-2)" "unprognostic (6.78e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (5.84e-2)" "unprognostic (3.43e-2)" "unprognostic (2.18e-2)" "unprognostic (2.60e-2)" "unprognostic (9.38e-2)" "prognostic unfavorable (7.68e-6)" "unprognostic (1.86e-1)" "unprognostic (2.59e-1)" "unprognostic (1.12e-1)" "unprognostic (4.69e-2)" 8.7 4.9 5.5 6.2 6.0 32.8 8.3 12.0 7.9 8.4 2.5 7.6 5.1 7.9 4.7 7.3 7.0 6.6 7.5 6.0 5.6 4.9 7.7 8.2 7.7 4.1 4.3 8.3 5.6 6.5 5.1 7.3 4.2 6.6 5.2 15.4 5.7 5.4 8.5 12.2 6.2 6.1 4.3 6.2 5.7 10.3 5.2 10.2 5.8 7.1 8.5 7.8 8.4 8.2 18.3 6.9 13.3 13.9 11.6 9.4 15.8 6.7 9.9 11.3 14.9 14.0 9.4 18.1 8.6 8.6 8.4 16.8 16.9 11.8 20.4 8.5 11.4 14.9 8.0 8.7 9.2 12.5 8.7 9.3 12.1 12.0 13.5 13.5 7.8 9.8 23.0 10.8 10.4 5.8 10.6 7.5 17.8 6.7 7.9 8.2 21.8 10.6 7.2 18.2 9.4 13.1 12.5 16.5 12.0 20.5 7.8 44.6 6.7 13.2 14.1 11.0 12.6 9.8 9.8 16.6 11.5 11.4 8.4 6.9 1.5 3.0 1.8 2.0 2.4 2.3 1.8 1.9 1.9 2.1 2.3 2.0 3.2 2.4 2.4 0.8 1.8 1.3 5.5 6.0 12.0 7.9 6.0 5.6 4.1 4.3 4.2 4.3 5.2 8.2 36.7 32.1 15.1 52.2 55.8 65.6 50.3 12.7 30.7 17.8 25.5 18.4 16.9 2.8 23.9 3.7 16.7 8.9 40.6 10.4 5.9 13.8 41.3 43.8 41.6 24.9 20.2 11.3 87.1 6.7 10.6 34.9 29.6 56.0 26.6 23.0 16.1 9.0 9.7 26.9 84.7 8.8 14.2 13.8 45.2 8.7 9.0 39.9 17.8 60.9 17.5 14.1 9.2 71.9 89.0 10.1 15.5 7.9 44.6 28.7 8.9 5.5 26.0 17.2 13.1 52.8 36.1 32.2 20.8 29.3 61.1 17.2 45.8 17.0 10.8 33.0 RNASEL "PRCA1, RNS4" ENSG00000135828 "Ribonuclease L" Q05823 1 182573634-182589256 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002633, CAB010906" Approved Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB010906: AB_477444, HPA002633: AB_1856314" "unprognostic (3.46e-2)" "unprognostic (9.10e-2)" "unprognostic (7.74e-2)" "unprognostic (1.13e-1)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (6.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "unprognostic (2.02e-1)" "unprognostic (5.43e-2)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.81e-1)" 5.6 6.4 3.2 8.8 3.5 3.6 5.9 3.4 3.9 6.6 3.7 8.1 7.0 6.5 9.6 6.2 5.2 6.9 3.4 2.9 3.4 6.2 3.5 6.9 9.6 3.4 3.5 11.3 3.1 7.9 5.4 6.9 3.6 7.2 9.0 5.7 5.0 8.3 2.0 5.4 8.0 7.1 2.8 8.9 7.8 2.2 3.6 8.0 9.1 4.5 9.9 6.0 6.3 3.3 2.6 3.6 1.5 0.6 7.9 13.7 2.8 4.9 6.1 4.9 4.5 2.1 5.6 5.6 8.4 5.6 2.2 4.7 3.6 5.1 1.9 4.5 3.1 6.6 1.3 0.3 4.1 12.4 12.5 9.8 11.4 2.6 0.7 3.1 2.1 8.2 2.4 4.2 4.3 3.8 3.6 5.1 1.2 8.4 1.0 5.3 1.2 2.9 5.2 3.4 0.7 0.2 4.4 5.3 4.3 3.9 5.4 13.6 2.8 2.5 2.0 2.7 2.7 3.7 1.3 0.7 4.0 7.5 3.8 41.7 14.8 53.1 9.4 15.8 12.4 10.3 11.1 10.1 12.4 7.9 17.3 12.8 55.3 10.9 30.3 14.7 10.0 10.5 3.2 3.5 3.4 3.9 2.9 3.4 3.4 3.5 3.6 2.8 3.6 3.3 4.5 6.4 4.2 5.2 6.5 1.0 2.9 4.9 1.2 4.3 2.8 2.4 1.3 1.5 9.0 3.7 4.2 4.2 8.2 14.8 7.9 6.7 0.0 2.5 9.6 5.1 2.4 4.8 4.2 1.8 3.7 6.4 7.7 3.4 5.7 5.5 3.9 1.6 6.2 1.7 6.6 9.3 8.2 9.7 1.2 0.8 2.8 5.8 0.0 1.9 7.3 8.7 5.2 6.0 3.6 2.2 3.2 6.4 2.7 3.5 7.2 7.3 9.1 6.1 19.7 5.8 5.2 0.4 0.9 4.5 1.0 2.6 7.5 12.1 4.0 4.6 RNASET2 "bA514O12.3, FLJ10907, RNASE6PL" ENSG00000026297 "Ribonuclease T2" O00584 6 166922113-166957191 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Endonuclease, Hydrolase, Lyase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 490.2;Glandular and luminal cells: 761.3;Hofbauer cells: 382.2;Kupffer cells: 484.7;Macrophages: 418.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "THP-1: 497.9" "HPA029013, HPA066509" Approved "Secreted to blood" NA NA 15000000 "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA029013: AB_10602922, HPA066509: AB_2685682" "unprognostic (4.18e-2)" "unprognostic (2.57e-1)" "unprognostic (1.44e-1)" "unprognostic (1.06e-1)" "unprognostic (4.13e-2)" "unprognostic (9.33e-2)" "unprognostic (1.76e-2)" "unprognostic (1.30e-1)" "unprognostic (1.15e-2)" "unprognostic (8.11e-2)" "unprognostic (1.79e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (1.70e-14)" "unprognostic (5.03e-2)" "unprognostic (7.34e-2)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" 34.9 35.0 50.1 68.6 50.4 124.3 50.2 52.2 65.9 161.5 52.3 74.0 57.6 49.1 140.7 24.8 134.6 69.6 19.8 49.5 53.5 31.2 52.4 47.2 117.4 68.2 54.3 36.2 144.7 40.7 26.3 43.5 66.2 51.9 89.9 8.3 112.8 94.1 7.3 25.4 65.4 27.8 61.9 195.1 72.9 13.3 59.1 43.8 76.7 12.1 86.9 54.9 32.2 79.8 12.8 14.2 12.6 37.8 57.0 40.6 8.4 15.8 21.2 7.3 7.4 33.7 19.9 11.1 149.8 41.3 16.7 41.0 20.8 18.6 4.3 15.9 35.1 10.2 20.6 84.6 19.1 152.7 37.3 23.9 33.6 4.3 2.7 30.4 10.1 21.7 20.9 94.5 10.9 44.9 12.6 109.5 6.4 140.0 13.0 25.0 16.6 131.7 136.3 9.9 4.4 28.7 32.0 100.4 8.3 22.3 13.1 497.9 19.3 14.9 9.8 43.7 13.5 15.0 19.5 1.4 32.3 149.2 10.3 116.9 185.6 674.8 29.1 277.0 53.4 136.7 159.9 72.3 226.4 119.6 128.4 41.4 438.9 30.7 368.8 369.3 90.8 179.8 50.1 50.4 52.2 65.9 49.5 53.5 68.2 54.3 66.2 61.9 59.1 79.8 21.8 19.2 29.3 10.1 270.1 43.3 116.4 45.1 72.3 10.5 97.0 95.1 9.5 47.1 28.0 38.6 0.0 63.4 286.8 133.7 23.5 59.2 10.3 490.2 78.9 44.9 75.4 27.6 13.6 27.4 58.8 45.8 80.0 761.3 71.7 38.6 19.2 20.0 382.2 13.5 37.1 204.0 24.4 484.7 187.7 11.3 35.4 418.2 58.7 113.4 146.1 24.4 64.9 14.6 1.7 74.1 324.8 29.3 158.6 61.2 178.5 19.6 19.0 7.1 26.3 31.9 18.6 10.0 23.1 58.3 34.5 27.8 149.2 15.3 193.0 103.9 RNF175 FLJ34190 ENSG00000145428 "Ring finger protein 175" Q8N4F7 4 153710160-153760024 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6;choroid plexus: 10.8" "Group enriched" "Detected in some" 5 "Early spermatids: 72.8;Excitatory neurons: 91.4;Inhibitory neurons: 95.7;Oligodendrocyte precursor cells: 38.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 8.8;HSkMC: 5.8;REH: 6.7;SH-SY5Y: 7.6;THP-1: 17.5;U-87 MG: 4.5" HPA035837 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA035837: AB_10601609" "unprognostic (3.23e-2)" "unprognostic (4.12e-2)" "unprognostic (3.34e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (3.11e-4)" "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (7.15e-4)" "unprognostic (1.17e-1)" "unprognostic (2.96e-3)" "unprognostic (6.30e-3)" "unprognostic (1.42e-1)" "unprognostic (3.63e-4)" "unprognostic (7.25e-3)" "unprognostic (3.27e-1)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" 1.5 2.5 18.8 2.9 19.2 6.1 0.8 15.0 27.6 3.0 10.8 0.6 0.1 0.2 0.9 0.6 0.5 1.0 4.0 18.3 21.8 0.2 0.4 1.4 1.2 17.7 15.3 0.1 0.3 0.0 4.0 0.1 17.6 2.4 0.1 3.5 1.4 3.4 0.1 0.7 0.5 0.1 14.1 2.5 0.3 1.6 18.0 0.1 0.2 0.5 0.6 0.5 1.5 17.5 0.2 0.0 8.8 0.0 0.0 0.6 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.0 0.0 0.0 6.7 0.0 0.3 0.0 0.1 0.0 7.6 0.0 0.0 0.2 0.1 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.9 0.0 0.0 1.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.9 0.0 2.2 0.0 2.4 0.0 2.1 0.0 0.6 0.6 18.8 19.2 15.0 27.6 18.3 21.8 17.7 15.3 17.6 14.1 18.0 17.5 0.1 0.0 0.5 6.8 0.0 0.4 0.1 0.6 0.6 0.7 0.1 0.6 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.8 0.0 0.1 0.2 0.0 0.4 91.4 0.0 0.0 2.9 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.0 95.7 0.0 0.0 5.9 2.9 14.6 0.0 1.5 1.8 2.8 0.7 0.8 0.0 38.7 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 1.6 0.0 0.0 0.3 1.5 1.3 0.0 0.3 0.0 0.6 0.0 0.0 0.2 RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178405-32180793 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 371.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "CAB034107: AB_2238618, HPA065032: AB_2685408" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.45e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (4.07e-1)" "prognostic favorable (2.44e-4)" "unprognostic (1.95e-1)" "unprognostic (8.93e-3)" "unprognostic (2.91e-3)" "unprognostic (8.84e-2)" "unprognostic (9.17e-2)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" 38.2 75.9 60.4 29.2 63.4 40.4 44.5 64.6 66.0 44.9 59.4 59.5 61.6 44.8 45.8 37.5 54.1 46.1 81.7 59.2 60.6 115.6 126.2 38.7 43.1 65.0 60.6 60.4 41.6 55.5 17.2 30.1 62.6 44.0 62.4 42.9 43.9 31.7 89.6 44.6 76.5 30.5 62.8 38.8 55.3 29.5 61.8 60.7 48.6 76.5 43.4 45.1 38.8 67.0 51.2 66.1 43.7 167.5 46.9 31.3 34.0 20.6 26.5 44.4 48.7 89.1 42.1 65.2 70.8 47.9 62.5 41.7 80.3 45.1 45.2 41.8 107.5 53.9 69.5 184.4 55.0 0.2 101.2 32.3 60.3 73.3 53.6 77.2 89.1 115.0 136.6 67.8 63.8 71.9 66.5 151.5 0.3 71.8 28.7 44.4 48.2 88.2 124.0 32.6 44.8 92.1 39.9 42.4 46.7 39.9 87.0 183.0 40.3 48.1 44.7 0.5 79.1 38.6 63.5 79.3 33.2 116.4 29.6 64.8 45.7 75.8 64.8 65.9 55.6 64.6 52.5 57.6 64.7 56.2 57.5 58.3 22.1 79.6 46.7 264.6 58.2 75.0 60.4 63.4 64.6 66.0 59.2 60.6 65.0 60.6 62.6 62.8 61.8 67.0 38.3 19.2 41.1 2.9 52.7 95.7 70.0 146.6 52.3 23.6 61.8 56.5 62.9 87.2 79.5 92.0 0.0 78.1 70.3 151.9 283.7 110.8 21.6 47.2 31.7 50.9 73.2 126.3 3.4 91.3 101.7 44.6 28.5 31.7 56.3 41.5 47.8 131.5 68.9 33.7 3.5 83.0 132.2 51.1 171.7 22.6 59.4 43.3 85.4 1.0 69.5 91.3 65.9 1.5 10.0 78.5 173.0 72.6 45.5 58.4 270.6 371.6 73.4 27.6 65.7 50.6 63.0 55.7 37.7 44.4 84.4 84.1 53.8 42.8 100.3 56.5 RPS10-NUDT3 ENSG00000270800 "RPS10-NUDT3 readthrough" 6 34284887-34426071 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 35.3;Alveolar cells type 2: 58.7;Club cells: 19.2;granulocytes: 10.1;Respiratory ciliated cells: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 27.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047027, HPA047268, HPA048084, HPA055953" Uncertain Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA047027: AB_2679907, HPA047268: AB_2680007, HPA048084: AB_2680255, HPA055953: AB_2682984" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.85e-2)" "unprognostic (7.54e-3)" "unprognostic (1.28e-2)" "unprognostic (6.85e-2)" "unprognostic (8.95e-2)" "unprognostic (2.67e-1)" "unprognostic (5.07e-2)" "unprognostic (1.36e-1)" "unprognostic (3.63e-1)" "unprognostic (5.17e-8)" "unprognostic (5.80e-2)" "unprognostic (9.49e-2)" "unprognostic (2.23e-1)" "unprognostic (1.42e-1)" 7.7 6.6 5.9 6.3 5.2 9.5 5.5 3.3 9.0 7.2 0.0 5.0 1.4 4.1 0.1 9.6 4.3 1.5 17.0 6.0 6.3 8.6 10.2 6.3 3.2 7.1 6.7 6.3 7.7 2.0 6.1 4.5 7.3 5.7 1.3 1.4 5.6 0.6 18.6 4.9 4.4 2.9 6.8 6.8 5.1 8.9 7.3 3.8 5.8 8.6 2.3 5.8 7.2 4.8 17.6 6.0 16.0 27.3 11.6 8.0 16.2 13.0 7.0 10.3 10.3 6.7 9.2 22.9 22.2 8.7 23.4 11.5 23.7 7.1 12.5 15.1 9.9 35.1 11.3 19.4 4.2 33.2 38.4 3.2 14.9 15.2 31.6 14.2 10.1 20.7 35.9 22.7 13.2 17.8 33.9 16.4 7.9 38.5 5.8 18.7 13.5 15.0 10.5 19.1 24.6 8.7 9.6 10.0 34.1 10.1 15.1 59.6 7.9 15.3 22.9 7.0 18.2 11.3 18.3 28.8 2.1 20.2 23.7 11.2 5.9 27.3 3.2 6.8 3.3 6.0 3.7 3.6 7.5 5.9 3.6 3.4 4.3 5.0 6.9 5.3 3.7 5.4 5.9 5.2 3.3 9.0 6.0 6.3 7.1 6.7 7.3 6.8 7.3 4.8 0.0 35.3 58.7 2.6 0.0 0.8 0.1 0.0 0.0 0.0 0.4 0.3 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 2.1 0.0 0.0 8.3 0.4 0.1 3.8 0.0 0.3 10.1 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.5 0.0 0.0 4.1 0.0 1.0 0.0 0.0 0.0 0.5 4.8 0.0 0.0 0.0 0.0 0.2 0.0 0.1 11.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 2.3 0.0 0.0 0.2 RSPO1 "FLJ40906, RSPONDIN" ENSG00000169218 "R-spondin 1" Q2MKA7 1 37611350-37634892 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 28.9;endometrium 1: 41.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 7.7;Breast myoepithelial cells: 15.6;Fibroblasts: 5.4;Langerhans cells: 2.9" "Cancer enriched" "Detected in some" 13 "ovarian cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.2;THP-1: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046154, HPA062923" Uncertain Approved Vesicles "Secreted in female reproductive system" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA046154: AB_10964912, HPA062923: " "unprognostic (1.50e-2)" "unprognostic (1.97e-3)" "unprognostic (5.99e-3)" "unprognostic (2.22e-1)" "unprognostic (1.76e-1)" "unprognostic (3.75e-6)" "unprognostic (1.84e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (2.08e-1)" "unprognostic (1.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.76e-2)" "unprognostic (3.21e-1)" "unprognostic (1.53e-2)" 11.3 0.1 0.0 0.8 0.1 0.1 7.9 0.1 0.1 28.9 0.0 1.8 1.1 41.4 2.2 3.1 20.0 2.7 0.7 0.1 0.0 0.8 0.1 4.0 1.9 0.1 0.1 2.1 0.5 0.1 0.1 0.4 0.1 6.7 0.5 0.1 1.3 1.8 0.0 6.6 3.3 13.1 0.0 0.8 4.0 0.2 0.1 0.0 0.0 0.5 3.0 1.5 19.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 7.7 15.6 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.9 0.1 0.9 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.4 0.1 0.3 0.0 0.0 0.1 RWDD2B "C21orf6, GL011" ENSG00000156253 "RWD domain containing 2B" P57060 21 29004384-29019360 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Spermatocytes: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 3.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018316 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA018316: AB_1845702" "unprognostic (1.96e-1)" "unprognostic (1.89e-2)" "unprognostic (1.42e-1)" "unprognostic (6.14e-2)" "unprognostic (6.67e-2)" "unprognostic (5.02e-2)" "unprognostic (1.75e-1)" "unprognostic (2.52e-2)" "unprognostic (1.80e-2)" "unprognostic (3.92e-2)" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (1.16e-1)" "unprognostic (6.77e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (2.75e-2)" 0.6 0.9 0.6 0.5 0.5 0.3 0.7 0.9 1.0 0.7 0.2 0.6 0.3 0.6 1.0 0.7 0.6 0.7 1.4 0.7 0.4 0.9 1.2 0.5 1.0 0.8 0.4 0.5 0.8 1.0 0.7 0.6 0.7 0.7 0.7 1.1 0.9 0.7 3.5 1.2 0.4 0.8 0.2 0.6 0.6 0.9 0.6 0.6 1.0 2.9 0.8 0.6 0.4 1.1 1.2 0.6 1.0 1.6 4.6 1.9 0.2 1.2 1.9 1.6 1.9 1.4 1.0 2.1 1.3 2.1 1.0 0.7 1.4 1.4 1.4 1.3 1.0 3.0 0.7 1.0 2.4 0.3 0.1 2.1 1.3 1.8 2.5 1.7 2.0 0.9 1.2 2.0 2.2 2.4 0.6 1.2 1.4 3.4 1.1 0.4 1.2 2.8 1.7 1.4 1.8 2.6 3.0 1.6 3.2 0.7 2.8 1.7 1.5 2.1 1.2 1.5 0.5 2.7 2.7 1.2 1.7 1.9 1.9 3.0 0.4 0.3 0.6 0.3 0.4 0.8 0.3 0.5 0.3 0.6 0.2 0.4 1.1 0.4 0.7 0.5 0.1 0.3 0.6 0.5 0.9 1.0 0.7 0.4 0.8 0.4 0.7 0.2 0.6 1.1 9.0 16.0 14.3 2.6 5.3 3.3 3.2 12.0 7.4 2.4 11.0 11.6 29.9 21.5 7.7 12.9 0.0 12.6 8.7 3.2 29.4 9.0 14.7 6.4 12.9 8.3 12.0 6.5 5.2 9.2 11.2 10.7 7.1 6.1 1.3 5.0 5.7 23.1 8.2 0.0 4.7 7.0 10.2 6.0 3.9 12.5 11.1 4.6 8.8 1.9 12.9 6.9 16.5 5.5 2.9 8.0 8.3 13.5 5.3 4.9 6.7 27.4 4.5 1.3 6.6 10.3 9.6 41.5 17.7 13.2 4.7 6.4 6.2 22.9 6.1 3.3 RXRA NR2B1 ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 218.9;Kupffer cells: 134.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 19.5" "Group enriched" "Detected in many" 5 "granulocytes: 19.5;monocytes: 12.9" "Cell line enhanced" "Detected in many" "HaCaT: 105.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Golgi apparatus" "CAB004565: AB_2184877, CAB005352: AB_2184874" "unprognostic (2.68e-1)" "unprognostic (7.94e-2)" "unprognostic (3.67e-2)" "unprognostic (7.22e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-3)" "prognostic favorable (7.02e-4)" "unprognostic (7.72e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" 40.5 22.7 33.5 14.5 36.4 18.9 11.2 25.5 29.4 12.2 16.9 16.6 25.8 13.5 8.7 28.5 16.5 13.6 19.4 27.1 30.2 16.0 32.9 18.8 8.2 32.9 31.3 21.7 25.4 45.1 3.5 14.5 30.8 15.6 10.0 5.4 21.7 17.1 106.5 88.1 28.0 11.1 30.4 25.1 14.7 7.9 42.7 6.0 17.6 51.9 7.6 16.2 8.2 22.6 19.6 36.4 14.7 21.9 42.8 19.1 66.7 14.1 16.1 9.6 6.5 20.7 28.0 0.0 25.8 22.5 15.1 105.5 7.7 32.8 2.9 26.3 7.2 0.1 47.5 30.0 20.4 18.8 4.8 29.0 52.1 11.5 10.6 12.9 12.8 1.6 26.0 1.1 8.7 61.8 1.1 59.5 17.5 63.4 16.9 7.4 30.3 36.7 12.2 64.3 17.2 10.5 37.3 46.9 10.6 7.1 44.9 78.8 16.5 16.2 23.4 17.4 9.7 1.7 0.2 0.4 11.6 33.9 12.7 1.3 8.1 6.6 1.4 12.9 0.2 0.3 0.9 1.0 3.2 0.1 0.2 1.2 19.5 2.2 11.2 0.7 1.2 3.2 33.5 36.4 25.5 29.4 27.1 30.2 32.9 31.3 30.8 30.4 42.7 22.6 32.1 32.1 22.9 36.2 4.6 34.5 16.5 21.1 12.5 6.0 16.7 14.4 38.8 72.9 26.2 9.2 25.0 30.1 11.0 72.3 1.9 13.9 4.3 19.8 16.6 28.9 9.6 30.9 9.1 14.1 29.5 23.7 17.9 17.4 1.3 21.3 71.0 218.9 31.9 33.7 17.6 21.2 10.2 134.2 30.0 18.8 32.3 50.4 12.4 10.3 80.4 36.5 14.4 29.1 6.0 15.9 32.4 21.1 7.4 17.7 55.6 19.9 34.4 19.9 19.7 34.6 30.6 0.9 9.4 34.4 46.9 23.9 12.6 15.5 27.5 32.8 SATB2 "FLJ21474, KIAA1034" ENSG00000119042 "SATB homeobox 2" Q9UPW6 2 199269500-199471266 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 13.9;intestine: 39.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 129.7;Enteroendocrine cells: 99.7;Excitatory neurons: 363.9;Intestinal goblet cells: 66.9;Paneth cells: 70.0;Undifferentiated cells: 84.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.0" "Group enriched" "Detected in many" 84 "basal ganglia: 10.9;cerebral cortex: 13.9;hippocampal formation: 4.6;white matter: 3.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 40.3;K-562: 45.1;THP-1: 59.8" "Region enhanced" "Detected in many" "cerebral cortex: 29.2" "Group enriched" "Detected in all" 5 "cerebral cortex: 46.4;hippocampal formation: 37.1" "HPA001042, CAB023669, HPA029543, CAB062562, CAB067751, CAB068229, CAB068230, CAB068231" Enhanced Supported Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB023669: AB_1129287, CAB062562: AB_2665615, CAB067751: AB_2665629, CAB068229: AB_2665628, CAB068230: AB_2665630, CAB068231: AB_2665631, HPA001042: AB_10601711, HPA029543: AB_10959737" "unprognostic (1.77e-2)" "unprognostic (1.90e-1)" "unprognostic (8.53e-3)" "unprognostic (4.77e-2)" "unprognostic (1.07e-1)" "unprognostic (9.39e-3)" "unprognostic (1.80e-1)" "unprognostic (5.54e-3)" "unprognostic (8.26e-2)" "unprognostic (3.75e-1)" "unprognostic (2.04e-2)" "unprognostic (1.13e-1)" "prognostic favorable (5.37e-8)" "unprognostic (1.14e-1)" "unprognostic (2.84e-1)" "unprognostic (7.95e-6)" "unprognostic (1.08e-3)" 2.7 4.8 0.0 4.3 10.9 0.3 2.2 0.0 13.9 2.7 0.0 34.2 1.5 1.7 0.9 0.8 1.4 1.3 0.7 4.6 0.0 4.0 3.0 0.9 0.5 0.0 0.0 1.9 3.9 2.1 1.0 0.6 0.0 1.9 39.5 0.8 1.5 2.8 2.2 1.8 5.7 3.0 0.0 0.7 1.0 2.8 0.0 0.2 1.6 2.7 1.0 1.6 3.1 3.9 2.6 1.7 17.6 8.1 8.3 9.9 1.3 6.2 8.9 4.4 5.7 0.4 5.8 0.9 0.2 13.3 6.9 0.5 14.0 3.7 7.0 9.4 12.3 40.3 4.1 4.9 1.9 18.7 17.1 4.8 6.4 8.8 5.6 11.3 0.4 6.0 45.1 0.0 12.8 0.9 0.8 22.9 3.2 2.0 2.9 1.7 6.0 0.1 6.6 0.6 3.8 0.0 3.1 0.0 9.5 3.1 3.6 59.8 6.2 31.5 5.9 10.1 16.6 2.6 8.9 25.9 21.7 14.6 25.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 13.9 4.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 1.4 0.0 1.1 18.6 0.6 1.8 2.7 0.5 0.6 2.4 0.9 0.4 1.5 0.0 0.7 0.0 4.2 0.1 0.2 129.7 1.9 0.3 1.0 0.9 3.9 1.5 99.7 0.0 363.9 2.7 0.3 3.6 0.0 0.7 0.0 1.6 1.8 5.4 0.8 0.0 3.5 66.9 0.0 2.5 3.0 0.9 2.5 1.0 5.4 9.4 0.6 0.5 0.0 21.1 34.1 1.2 70.0 1.2 0.0 4.3 19.1 7.6 0.2 0.5 0.0 1.7 10.4 6.1 4.1 0.8 3.0 0.1 1.3 3.9 84.7 2.2 SCMH1 Scml3 ENSG00000010803 "Scm polycomb group protein homolog 1" Q96GD3 1 41027200-41242154 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 125.4;Excitatory neurons: 161.3;Inhibitory neurons: 213.0;Microglial cells: 102.1;Oligodendrocyte precursor cells: 154.3;Oligodendrocytes: 77.9;Spermatocytes: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048898, HPA053292" Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA048898: , HPA053292: AB_2797246" "unprognostic (6.02e-2)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (3.82e-4)" "unprognostic (1.98e-2)" "unprognostic (8.77e-2)" "unprognostic (8.93e-3)" "unprognostic (2.77e-2)" "unprognostic (1.40e-1)" "unprognostic (7.38e-2)" "unprognostic (9.47e-2)" "unprognostic (1.63e-1)" "unprognostic (8.08e-2)" "prognostic favorable (5.80e-4)" 22.0 24.0 15.2 11.3 15.9 17.8 23.2 16.5 18.1 32.0 18.6 54.6 12.7 35.4 20.5 14.0 33.1 15.8 39.3 16.1 16.9 29.8 19.7 20.6 10.4 13.6 14.7 36.3 40.1 34.7 27.6 11.0 13.1 40.4 17.0 21.0 27.5 30.7 44.9 13.3 23.4 24.6 12.2 15.5 32.5 32.8 16.7 16.6 24.1 34.2 10.5 38.9 21.3 14.1 19.5 12.8 29.9 27.5 13.4 25.4 0.1 15.4 26.7 25.2 26.0 12.3 24.6 35.4 11.4 28.1 21.1 4.8 23.3 20.6 21.6 24.7 17.8 16.6 17.7 31.2 58.2 35.7 26.2 27.7 20.5 16.7 40.2 30.5 25.7 43.3 15.7 26.8 25.0 10.6 36.0 30.8 27.7 16.4 13.5 39.3 31.3 21.0 20.4 24.1 21.0 22.5 26.7 21.1 22.1 20.2 18.8 90.7 19.0 26.3 20.4 16.4 28.5 27.1 16.2 38.6 16.5 31.5 24.4 0.6 0.6 1.2 1.6 1.1 2.0 2.4 1.9 1.5 1.9 1.1 1.3 1.1 0.0 1.6 0.2 3.9 1.4 0.9 15.2 15.9 16.5 18.1 16.1 16.9 13.6 14.7 13.1 12.2 16.7 14.1 7.1 9.6 10.8 125.4 9.4 6.6 25.8 11.5 26.7 17.0 16.4 17.0 14.9 18.6 7.4 12.9 16.7 7.3 10.8 7.2 1.9 11.4 9.4 7.2 13.8 9.6 8.4 16.0 161.3 21.3 3.3 11.4 15.3 13.1 5.1 11.9 8.9 7.3 6.2 8.4 213.0 7.4 8.2 3.3 6.5 12.4 16.4 3.2 8.8 102.1 2.7 6.9 2.1 154.3 77.9 12.4 6.2 18.0 20.2 23.3 10.4 18.1 5.8 14.2 19.7 11.9 10.3 54.3 26.1 6.1 3.7 4.8 7.4 3.5 12.4 14.5 SCNM1 MGC3180 ENSG00000163156 "Sodium channel modifier 1" Q9BWG6 1 151156664-151170296 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "THP-1: 269.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052439, HPA054324" Uncertain Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA052439: AB_2681834, HPA054324: AB_2682451" "unprognostic (1.20e-1)" "unprognostic (4.42e-2)" "unprognostic (6.13e-2)" "unprognostic (7.79e-2)" "unprognostic (8.96e-3)" "unprognostic (1.77e-1)" "unprognostic (4.25e-3)" "unprognostic (1.25e-2)" "unprognostic (1.77e-1)" "prognostic favorable (1.23e-4)" "unprognostic (1.38e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (2.17e-13)" "unprognostic (8.74e-2)" "unprognostic (1.13e-1)" "unprognostic (8.48e-2)" "unprognostic (9.71e-2)" 27.6 19.9 37.6 27.5 37.7 46.1 24.3 38.6 40.6 24.4 34.3 25.8 20.1 25.2 17.3 25.8 21.8 18.7 23.2 36.6 38.0 22.8 16.8 21.6 39.9 38.7 37.9 20.8 15.0 17.6 16.4 21.1 38.1 23.7 17.4 13.7 20.2 17.2 65.0 29.1 23.4 21.6 37.9 34.1 21.3 18.3 38.4 35.0 18.0 34.3 34.7 29.8 23.0 40.0 46.5 32.0 35.0 41.4 47.9 35.9 58.3 35.9 41.5 85.7 66.5 69.9 44.2 73.3 57.1 39.0 22.4 61.5 41.3 33.1 41.4 46.6 45.7 63.5 44.5 45.5 69.2 85.2 60.0 37.8 63.3 60.3 53.4 40.2 52.4 50.5 51.7 54.7 42.6 114.0 61.2 132.0 89.0 72.1 49.2 82.3 41.7 91.7 46.7 30.6 43.0 69.0 40.5 65.4 83.5 43.2 60.5 269.9 38.7 40.8 38.3 42.5 78.1 70.7 104.3 117.4 42.5 89.5 53.6 286.7 189.1 203.3 80.4 146.0 77.6 125.9 97.4 92.0 254.9 112.7 89.0 76.9 190.5 131.6 95.1 260.8 131.4 182.3 37.6 37.7 38.6 40.6 36.6 38.0 38.7 37.9 38.1 37.9 38.4 40.0 21.0 3.2 15.2 0.0 33.7 26.6 17.8 47.8 33.0 19.9 20.2 26.3 32.9 17.2 34.1 29.5 18.8 36.6 52.3 21.4 54.8 34.0 33.5 24.0 23.1 26.9 14.4 34.7 0.0 31.9 33.6 26.5 26.0 15.2 40.5 15.8 27.5 11.9 74.1 8.4 0.0 20.4 54.9 57.2 62.0 25.3 31.1 55.1 21.4 0.0 67.6 25.7 64.9 0.0 0.0 41.9 31.2 21.4 23.2 16.6 36.3 37.1 38.5 16.9 32.9 14.2 43.9 27.9 15.1 33.6 18.3 27.5 37.8 14.7 16.8 22.0 SDHC "CYB560, cybL, PGL3" ENSG00000143252 "Succinate dehydrogenase complex subunit C" Q99643 1 161314381-161363206 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 776.7;Proximal tubular cells: 916.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.48e-2)" "unprognostic (6.88e-2)" "unprognostic (6.38e-3)" "unprognostic (1.86e-2)" "unprognostic (1.90e-2)" "unprognostic (5.02e-2)" "unprognostic (7.08e-2)" "unprognostic (2.33e-1)" "unprognostic (7.38e-2)" "unprognostic (1.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "prognostic favorable (2.20e-4)" "unprognostic (9.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.19e-3)" "unprognostic (3.77e-1)" 128.9 143.7 73.7 64.1 79.7 60.5 100.3 84.5 85.1 78.7 92.9 118.9 127.8 70.9 76.0 109.7 98.6 63.3 154.1 68.4 83.4 285.7 319.4 65.5 74.7 78.8 79.1 69.2 62.5 173.6 52.4 73.1 76.7 77.3 132.2 84.3 74.8 84.7 277.4 69.8 101.4 101.4 85.1 62.8 89.9 52.7 84.8 93.1 89.5 288.4 105.1 88.4 61.3 85.6 161.1 129.7 157.5 147.7 248.3 213.3 196.3 150.9 190.3 180.3 137.3 185.4 208.7 53.7 190.6 214.8 121.6 178.5 244.3 214.2 193.2 185.6 205.6 110.2 106.6 196.7 126.9 193.8 109.1 211.5 181.7 174.3 119.4 167.9 177.5 164.0 178.9 43.8 266.3 167.0 152.4 112.5 145.4 376.3 123.7 131.6 151.0 217.1 330.3 167.8 118.3 180.7 211.0 385.1 225.4 207.9 342.1 259.3 133.5 103.7 125.1 127.9 147.3 173.3 287.8 269.4 140.3 139.2 193.6 88.6 111.0 65.7 76.6 99.6 79.6 68.6 66.2 75.4 136.1 65.7 71.2 71.0 52.0 66.9 87.5 100.6 78.3 130.0 73.7 79.7 84.5 85.1 68.4 83.4 78.8 79.1 76.7 85.1 84.8 85.6 50.9 44.8 59.4 14.7 70.1 61.8 151.2 342.6 59.7 74.9 81.4 58.3 94.0 131.5 163.5 150.8 64.6 248.0 65.5 95.9 776.7 218.4 18.6 87.1 63.8 80.7 66.8 81.4 19.3 145.2 248.5 79.8 79.5 62.6 58.3 66.6 83.2 249.1 237.3 72.3 27.4 103.4 215.7 100.6 74.4 34.7 102.9 94.6 129.9 9.4 176.1 107.8 107.1 17.6 24.5 142.7 89.5 109.1 71.9 100.2 139.1 916.5 177.9 69.3 52.6 74.5 94.4 115.3 114.4 111.2 76.4 307.6 72.0 215.7 154.2 155.0 SEMG1 "CT103, SEMG" ENSG00000124233 "Semenogelin 1" P04279 20 45207033-45209768 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 147 "seminal vesicle: 30405.5" "Group enriched" "Detected in some" 18 "Basal prostatic cells: 7.5;Prostatic glandular cells: 3.4" "Cancer enriched" "Detected in some" 14 "prostate cancer: 20.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 239 "eosinophil: 26.8" "Lineage enriched" "Detected in single" 269 "granulocytes: 26.8" "Cell line enhanced" "Detected in some" "NTERA-2: 1.3;THP-1: 3.1" "HPA042476, HPA064892" Enhanced "Secreted in male reproductive system" NA NA 7000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 43: THP-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" "HPA042476: AB_10794799, HPA064892: AB_2732724" "unprognostic (3.71e-1)" "unprognostic (2.92e-2)" "unprognostic (1.44e-1)" "unprognostic (3.32e-1)" "unprognostic (1.11e-2)" 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 207.1 0.0 0.0 0.0 30405.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 SERF2 "4F5REL, FAM2C, H4F5rel, HsT17089" ENSG00000140264 "Small EDRK-rich factor 2" P84101 15 43777087-43804427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056613 Uncertain Nucleoplasm,Nucleoli NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA056613: " "unprognostic (3.29e-1)" "unprognostic (7.29e-2)" "unprognostic (1.13e-3)" "prognostic favorable (5.33e-4)" "unprognostic (1.40e-1)" "unprognostic (3.91e-2)" "unprognostic (6.06e-2)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (2.50e-1)" "unprognostic (3.04e-1)" "unprognostic (1.36e-1)" "unprognostic (3.37e-2)" "unprognostic (2.84e-1)" "unprognostic (3.35e-2)" "unprognostic (2.76e-2)" "unprognostic (9.42e-2)" 760.6 1067.4 704.4 446.7 726.4 944.9 619.4 750.2 906.3 650.8 1027.1 728.4 443.4 509.9 776.2 887.9 456.8 469.4 1187.9 698.1 712.2 1002.2 1328.7 700.8 686.4 737.1 725.3 474.3 795.1 490.9 569.3 484.2 734.7 794.5 631.9 72.8 823.7 312.8 636.9 631.1 593.2 507.4 739.4 745.3 784.3 400.2 759.4 450.7 706.6 723.6 628.9 595.0 634.1 758.8 497.5 770.8 573.8 792.9 1963.2 1431.3 438.9 844.8 1042.5 540.4 682.7 991.5 470.0 250.4 694.7 1429.2 698.7 641.1 454.6 623.8 271.1 699.6 526.2 610.9 1074.9 1936.8 934.7 581.8 1235.8 1349.9 810.5 425.8 452.1 836.1 783.5 680.7 630.2 1593.5 1067.4 1441.8 758.6 1337.2 501.5 1849.7 885.1 743.9 382.6 1147.2 1462.5 1695.7 450.6 481.1 458.9 1871.5 463.9 488.4 1574.7 2363.9 682.9 920.0 469.0 1409.4 669.3 593.3 886.2 1837.8 989.2 1032.8 980.4 4033.8 5391.9 5884.9 2716.6 5055.2 2481.3 3853.8 2938.5 2784.5 4649.4 3901.8 2713.3 2731.7 3154.6 2568.8 4495.9 6486.5 3793.5 12856.7 704.4 726.4 750.2 906.3 698.1 712.2 737.1 725.3 734.7 739.4 759.4 758.8 1269.2 506.4 789.0 0.0 1149.8 1151.3 1379.1 3393.0 861.6 53.9 2373.1 2483.2 2229.8 1338.2 2099.5 1736.1 54.2 2660.9 1475.6 2388.2 3897.3 1707.6 576.8 1243.6 1343.1 1283.3 1167.5 1310.8 0.5 2255.2 3410.2 1489.3 1403.7 1261.0 785.9 775.2 1532.4 2884.5 3545.2 47.1 0.5 2862.6 2278.6 2262.1 2298.5 319.2 1225.3 2102.8 1817.8 0.0 2626.4 544.5 1881.6 1.5 0.3 1804.7 2363.9 992.2 1546.7 2188.9 3013.2 5083.6 1950.6 148.4 604.8 680.1 1737.3 750.2 381.1 1725.5 1556.5 3275.8 1216.9 1446.6 2042.5 2819.5 SERPINI2 "MEPI, PANCPIN, PI14, TSA2004" ENSG00000114204 "Serpin family I member 2" O75830 3 167441789-167479004 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 133 "pancreas: 1370.0" "Cell type enhanced" "Detected in some" "Astrocytes: 37.5;Exocrine glandular cells: 93.4;Respiratory ciliated cells: 22.9" "Cancer enriched" "Detected in some" 6 "pancreatic cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "THP-1: 9.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 8.7" "Secreted to digestive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 43: THP-1 - Innate immune response" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (1.88e-2)" "unprognostic (2.23e-3)" "unprognostic (1.14e-1)" "unprognostic (5.27e-2)" "unprognostic (1.17e-2)" "unprognostic (1.29e-2)" "unprognostic (1.11e-2)" "unprognostic (2.04e-1)" "unprognostic (3.13e-1)" "unprognostic (1.76e-5)" "unprognostic (5.35e-2)" "unprognostic (4.16e-2)" 0.1 0.1 3.7 0.0 2.9 0.4 0.1 4.4 1.5 0.2 10.2 0.1 1.0 0.2 0.2 0.2 3.9 0.0 0.5 2.5 3.7 0.2 0.0 1.0 0.1 9.6 7.7 0.5 1370.0 0.0 0.4 0.0 7.1 0.2 0.0 0.0 0.4 0.0 0.0 0.1 1.9 0.1 9.4 0.2 0.3 0.1 4.3 0.0 0.0 0.2 0.1 0.1 0.1 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 9.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.7 2.9 4.4 1.5 2.5 3.7 9.6 7.7 7.1 9.4 4.3 5.8 0.0 0.0 1.1 37.5 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 5.9 0.1 0.1 0.0 0.0 3.6 93.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 1.2 0.0 0.0 2.0 0.9 4.8 0.0 0.0 0.0 0.0 0.7 0.0 22.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 SEZ6L2 "FLJ90517, PSK-1" ENSG00000174938 "Seizure related 6 homolog like 2" Q6UXD5 16 29871159-29899547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 101.6;pituitary gland: 91.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 236.6;Cone photoreceptor cells: 185.6;Enteroendocrine cells: 132.5;Horizontal cells: 188.4;Rod photoreceptor cells: 230.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064471 Enhanced NA NA 5600000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA064471: AB_2685271" "unprognostic (2.56e-2)" "prognostic unfavorable (7.46e-4)" "prognostic unfavorable (1.31e-4)" "unprognostic (2.11e-1)" "prognostic unfavorable (5.24e-4)" "unprognostic (1.27e-1)" "unprognostic (1.67e-2)" "unprognostic (2.71e-2)" "unprognostic (8.22e-2)" "unprognostic (1.85e-1)" "unprognostic (1.43e-3)" "unprognostic (8.31e-2)" "unprognostic (1.04e-1)" "unprognostic (8.22e-2)" "unprognostic (2.30e-1)" "unprognostic (2.12e-1)" "unprognostic (1.08e-1)" 4.6 23.2 47.3 1.4 43.6 0.1 4.5 37.0 101.6 11.8 0.0 4.5 10.3 9.0 0.7 1.1 4.0 9.6 2.3 43.7 93.1 7.8 0.6 4.5 0.9 69.2 29.2 5.4 41.2 21.3 91.9 3.0 62.5 14.4 3.4 25.8 22.1 4.3 1.0 2.4 5.8 4.1 21.1 1.9 16.6 11.2 46.4 0.4 1.0 0.0 1.4 3.1 1.8 57.3 1.4 11.6 0.9 11.0 0.1 0.5 7.7 14.4 6.7 13.3 7.3 17.2 53.8 5.8 76.7 17.5 11.1 4.9 4.4 3.4 4.0 0.1 9.6 0.9 9.2 35.7 28.7 0.0 33.9 32.3 6.5 15.8 4.3 48.1 1.0 5.1 1.8 34.5 6.7 59.4 0.2 0.1 17.2 19.6 19.8 0.0 0.0 1.6 12.1 5.1 51.3 41.2 4.9 36.5 2.3 9.1 34.3 51.3 0.6 44.3 21.6 0.3 0.9 3.9 3.6 0.3 53.8 9.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 43.6 37.0 101.6 43.7 93.1 69.2 29.2 62.5 21.1 46.4 57.3 3.2 3.2 16.4 4.2 0.8 2.9 9.4 6.2 2.8 236.6 49.6 30.6 8.6 77.2 5.5 3.7 185.6 0.3 0.5 19.9 0.0 61.7 2.8 25.1 48.2 4.9 132.5 0.0 28.6 39.4 2.7 12.2 34.7 33.4 1.3 3.5 2.5 0.2 1.3 188.4 46.3 32.9 10.2 0.3 0.0 5.4 1.2 1.0 12.4 3.7 0.6 20.8 0.0 5.5 13.1 45.2 22.1 1.9 1.4 23.5 15.3 5.0 3.4 230.3 13.1 0.9 15.2 8.2 4.7 1.0 1.4 1.4 0.7 26.8 29.0 9.1 SFMBT2 KIAA1617 ENSG00000198879 "Scm like with four mbt domains 2" Q5VUG0 10 7158624-7411486 "Predicted intracellular proteins" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 27.7" "Cell type enriched" "Detected in many" 4 "Microglial cells: 618.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 23.0;REH: 21.0;RPMI-8226: 20.2;SH-SY5Y: 16.6;THP-1: 25.0;U-937: 16.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035447, HPA035448, HPA070388" Uncertain Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear speckles" "HPA035447: AB_2674628, HPA035448: AB_10669904, HPA070388: " "unprognostic (4.36e-2)" "unprognostic (2.29e-2)" "unprognostic (4.36e-2)" "unprognostic (1.42e-3)" "unprognostic (3.23e-2)" "unprognostic (2.05e-3)" "unprognostic (4.65e-1)" "unprognostic (4.56e-1)" "unprognostic (1.03e-1)" "unprognostic (6.51e-2)" "unprognostic (5.57e-2)" "unprognostic (1.38e-1)" "unprognostic (2.41e-2)" "unprognostic (1.26e-1)" "unprognostic (9.17e-3)" "unprognostic (5.37e-3)" "unprognostic (7.29e-2)" 3.8 4.1 13.0 5.9 13.1 6.6 5.5 10.2 9.8 3.4 5.1 2.8 2.0 4.0 3.7 1.1 4.0 3.5 4.0 7.5 17.6 3.0 1.3 4.7 7.3 20.4 15.0 9.1 1.3 5.7 6.4 3.4 17.1 6.6 3.2 18.0 2.3 3.1 4.2 1.7 4.0 3.3 12.7 9.0 3.1 1.8 27.7 4.5 6.8 2.6 5.8 4.1 4.2 19.0 0.0 4.0 0.3 0.0 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.0 1.1 7.6 0.0 0.0 0.0 1.9 7.6 0.0 0.0 0.4 7.9 0.0 13.0 0.0 0.7 8.0 1.1 1.1 0.4 0.0 0.3 0.0 0.1 10.0 11.5 23.0 0.0 3.5 7.0 14.3 1.6 0.0 0.0 21.0 2.2 20.2 0.0 0.8 2.0 16.6 0.0 0.1 0.0 2.1 1.3 25.0 0.0 0.0 2.6 0.4 0.2 10.1 13.3 0.0 1.1 16.5 0.3 0.1 0.2 1.1 0.7 2.3 0.4 0.0 0.2 0.5 0.4 0.0 1.0 0.6 0.1 0.9 4.6 3.1 0.0 0.2 13.0 13.1 10.2 9.8 7.5 17.6 20.4 15.0 17.1 12.7 27.7 19.0 8.2 0.0 5.2 148.2 10.2 1.5 1.5 0.0 1.2 8.1 9.3 8.6 9.7 1.5 0.6 0.0 81.3 7.7 22.1 0.1 0.0 0.4 0.2 0.8 15.8 10.1 4.2 6.1 77.3 0.2 2.5 4.2 2.0 3.5 4.5 7.1 5.7 1.1 15.5 0.0 103.9 0.0 0.0 15.7 9.9 0.8 5.0 26.3 5.4 618.3 11.4 12.4 15.5 26.2 113.7 0.1 0.0 2.2 25.8 11.4 0.0 0.3 0.7 34.1 0.0 4.4 2.6 0.3 3.9 0.2 1.3 4.4 25.8 2.5 0.2 0.6 SFT2D1 "C6orf83, MGC19825, pRGR1" ENSG00000198818 "SFT2 domain containing 1" Q8WV19 6 166319728-166342576 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014677 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA014677: AB_2238986" "unprognostic (8.45e-2)" "unprognostic (1.43e-3)" "unprognostic (2.29e-1)" "unprognostic (1.41e-2)" "unprognostic (6.77e-2)" "prognostic unfavorable (7.47e-4)" "prognostic unfavorable (2.19e-5)" "unprognostic (3.64e-1)" "unprognostic (1.68e-1)" "unprognostic (1.68e-1)" "unprognostic (6.53e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.59e-4)" "unprognostic (4.20e-2)" "unprognostic (5.05e-2)" "prognostic favorable (5.90e-4)" "unprognostic (2.75e-2)" 40.8 43.9 55.0 35.6 61.7 35.8 45.9 62.3 76.2 35.4 54.0 52.1 39.2 26.5 68.2 36.6 33.8 34.4 30.5 54.5 59.0 51.0 24.5 37.0 50.9 64.0 59.0 31.9 51.1 36.1 17.3 48.9 65.3 47.5 50.1 12.9 70.7 28.0 22.2 24.7 39.0 24.8 62.9 41.9 50.7 26.9 57.2 41.7 46.3 27.5 47.9 40.4 29.4 72.4 47.1 39.9 41.9 86.3 76.1 65.9 56.4 70.7 69.6 56.8 85.5 80.2 103.3 43.9 55.7 68.8 90.2 59.7 62.5 67.0 88.3 58.8 88.4 53.0 35.4 133.4 65.9 134.9 106.5 61.1 78.9 65.5 58.3 81.8 31.3 73.1 96.1 46.8 90.3 68.5 42.1 241.5 40.2 154.5 36.2 28.6 45.0 105.4 141.6 46.1 8.0 34.3 45.6 87.8 73.0 48.1 46.4 252.3 28.6 33.4 60.4 87.4 79.7 40.7 32.3 50.6 70.4 84.8 85.5 141.1 90.7 126.3 62.1 98.6 38.7 88.1 47.3 52.3 103.4 72.5 50.3 51.7 166.0 58.9 107.3 204.9 79.4 92.7 55.0 61.7 62.3 76.2 54.5 59.0 64.0 59.0 65.3 62.9 57.2 72.4 45.6 41.7 66.5 25.1 103.4 86.5 127.8 262.4 59.2 10.0 136.0 103.6 25.0 51.5 143.9 108.5 0.0 153.0 154.2 109.3 90.1 154.5 70.3 52.0 49.9 55.8 28.8 63.3 15.6 126.8 259.4 81.5 61.2 73.9 149.0 31.3 65.3 30.6 211.6 15.2 13.6 162.5 168.9 178.5 178.4 25.2 85.1 143.5 99.6 21.5 198.3 31.7 111.2 16.6 71.5 155.4 146.5 47.4 108.5 239.2 115.5 140.4 96.0 9.1 85.5 69.5 64.0 159.0 93.4 72.9 102.9 131.2 74.9 63.2 131.4 194.0 SH3KBP1 CIN85 ENSG00000147010 "SH3 domain containing kinase binding protein 1" Q96B97 X 19533977-19887600 "Disease related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.8;monocytes: 289.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003351, HPA003355, CAB021892" Enhanced Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB021892: , HPA003351: AB_1079956, HPA003355: AB_1079954" "unprognostic (1.17e-2)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (4.65e-3)" "unprognostic (1.62e-1)" "unprognostic (2.88e-2)" "unprognostic (6.47e-2)" "unprognostic (9.91e-2)" "unprognostic (9.75e-2)" "unprognostic (1.76e-3)" "unprognostic (5.96e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (4.00e-1)" "unprognostic (1.54e-1)" "unprognostic (3.94e-2)" "unprognostic (4.92e-2)" 45.1 11.0 17.1 45.5 16.8 68.6 26.6 14.2 20.3 18.2 47.3 37.1 13.7 10.6 11.3 8.5 11.9 21.2 24.4 16.4 20.8 13.5 15.6 26.0 68.1 19.9 22.9 8.7 6.9 14.4 11.9 32.5 20.3 6.7 35.3 5.1 10.4 7.4 13.0 24.0 18.4 14.8 18.5 37.0 18.9 5.7 26.0 55.0 20.5 32.4 68.7 17.7 11.2 27.1 52.5 54.3 8.4 19.4 41.6 80.0 44.2 46.4 67.4 23.3 37.2 37.2 105.6 97.4 47.6 67.5 67.0 5.9 19.8 18.4 37.3 32.3 13.4 21.2 13.6 30.1 27.2 134.0 160.2 47.4 18.0 48.5 141.9 64.6 35.4 67.6 8.0 114.2 59.7 23.5 80.4 135.4 14.8 63.1 71.2 49.1 82.0 9.1 27.1 10.6 6.0 6.2 43.2 5.6 65.3 53.8 5.4 155.2 113.6 40.6 34.9 52.2 51.9 165.6 119.0 86.0 86.5 109.4 183.5 49.2 104.7 171.1 180.2 77.7 140.4 55.4 174.2 187.8 132.6 50.3 143.3 142.5 210.0 76.5 96.9 148.4 224.1 195.9 17.1 16.8 14.2 20.3 16.4 20.8 19.9 22.9 20.3 18.5 26.0 27.1 40.3 16.0 54.4 5.5 75.6 12.0 3.5 7.5 5.2 5.1 5.4 6.2 78.1 11.5 25.0 9.2 16.7 26.2 174.3 207.8 1.9 8.3 0.7 6.3 28.5 26.5 50.8 23.3 72.3 18.9 39.3 56.9 23.4 8.3 96.6 5.9 27.8 17.6 55.8 8.4 126.3 34.4 10.2 87.4 102.1 1.9 52.8 113.0 33.8 108.7 289.2 0.1 175.1 87.0 145.9 48.0 153.3 38.4 63.5 3.5 26.4 40.3 20.1 2.8 59.2 12.1 72.2 24.3 22.7 1.9 10.9 22.6 138.7 26.7 59.4 7.7 SHOX2 "OG12, OG12X, SHOT" ENSG00000168779 "Short stature homeobox 2" O60902 3 158095905-158106420 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 7.8;brain: 26.4" "Cell type enriched" "Detected in some" 6 "Early spermatids: 90.3" "Cancer enhanced" "Detected in many" "glioma: 3.4" "Region enhanced" "Detected in many" "thalamus: 26.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.2;THP-1: 38.7" "Group enriched" "Detected in many" 5 "midbrain: 36.0;thalamus: 54.8" "Group enriched" "Detected in some" 6 "midbrain: 10.6;pons: 16.3;thalamus: 32.1" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (2.62e-1)" "unprognostic (6.32e-2)" "unprognostic (3.32e-2)" "unprognostic (1.08e-3)" "unprognostic (1.51e-1)" "unprognostic (1.69e-3)" "unprognostic (2.28e-3)" "unprognostic (7.66e-2)" "unprognostic (7.35e-2)" "unprognostic (2.23e-1)" "unprognostic (6.31e-2)" "unprognostic (8.75e-3)" "unprognostic (0.00e+0)" "unprognostic (4.20e-3)" "unprognostic (2.12e-1)" "unprognostic (3.95e-2)" "unprognostic (2.76e-3)" 7.8 0.1 8.9 0.0 0.5 0.1 5.4 0.0 1.1 3.9 0.0 0.1 0.0 0.4 0.1 0.0 0.2 0.2 3.4 0.1 6.1 0.0 0.0 0.2 1.7 10.6 13.0 0.2 0.1 0.3 0.2 0.2 7.0 0.1 0.0 0.0 2.2 0.4 1.3 2.2 0.1 0.0 0.5 0.0 0.2 3.4 26.4 0.0 0.5 0.4 0.3 0.4 1.0 0.2 5.5 0.6 0.3 8.1 24.2 15.3 1.5 8.9 3.4 4.8 8.2 1.8 0.7 1.2 0.2 12.8 9.5 0.1 10.1 0.0 1.9 5.1 2.9 13.7 2.7 0.0 0.0 1.2 10.7 6.9 0.3 4.4 0.5 14.8 0.0 0.7 3.8 0.9 2.1 0.3 0.0 0.7 0.0 0.1 0.5 6.2 7.4 1.4 0.0 0.0 2.7 20.5 1.0 0.2 5.2 0.1 0.2 38.7 0.5 15.0 3.1 16.6 14.8 1.1 2.9 0.9 14.5 7.3 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 8.9 0.5 0.0 1.1 0.1 6.1 10.6 13.0 7.0 0.5 26.4 0.2 3.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.2 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 90.3 0.1 1.7 0.9 0.0 0.0 0.0 0.2 0.7 9.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 1.9 1.2 13.9 2.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 13.1 1.1 8.5 5.7 2.8 0.0 0.4 0.3 0.1 0.0 0.2 0.0 SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 11 "Hofbauer cells: 78.6;Kupffer cells: 93.4;Macrophages: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Cell line enriched" "Detected in single" 19 "THP-1: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" NA NA 260000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" 23.0 13.7 2.0 7.7 2.9 12.3 8.6 1.9 6.5 1.8 7.5 10.2 5.1 2.0 1.8 2.2 7.0 8.5 6.4 1.8 2.2 3.9 8.4 16.7 12.7 10.2 3.3 2.7 1.6 0.5 2.3 18.8 10.9 1.9 6.6 0.3 5.4 1.2 3.7 3.0 11.2 7.7 5.0 18.9 5.1 2.5 10.9 3.6 3.7 2.6 1.9 7.6 3.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 2.0 2.9 1.9 6.5 1.8 2.2 10.2 3.3 10.9 5.0 10.9 3.9 0.5 3.2 4.4 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.0 0.3 2.4 0.0 0.6 0.0 2.1 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.2 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.3 0.0 0.0 93.4 6.3 0.1 0.0 42.6 0.0 3.7 2.1 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 1.4 1.0 0.0 0.1 0.6 0.6 1.9 0.4 0.0 0.0 0.0 SIKE1 "FLJ21168, SIKE" ENSG00000052723 "Suppressor of IKBKE 1" Q9BRV8 1 114769479-114780685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024177, HPA025726" Supported Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Focal adhesion sites" Vesicles "HPA024177: AB_1848798, HPA025726: AB_1848800" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (3.53e-2)" "unprognostic (4.52e-3)" "unprognostic (4.10e-1)" "unprognostic (6.04e-2)" "unprognostic (3.37e-3)" "unprognostic (2.11e-1)" "unprognostic (1.72e-2)" "unprognostic (2.52e-2)" "unprognostic (1.94e-2)" "unprognostic (7.91e-2)" "unprognostic (2.38e-2)" "unprognostic (3.86e-2)" "unprognostic (9.06e-2)" "unprognostic (2.95e-3)" "unprognostic (1.05e-1)" 8.8 6.9 5.9 9.7 6.0 9.8 9.6 8.5 6.7 9.1 5.7 8.6 9.8 9.4 7.6 7.7 6.0 6.9 7.3 4.9 7.7 10.8 12.2 6.8 12.1 7.0 6.8 8.6 6.8 9.7 4.9 9.6 7.0 7.6 9.4 8.0 7.3 7.5 6.7 13.4 8.5 9.2 6.4 9.5 8.4 5.6 8.2 13.6 10.1 7.4 12.0 7.2 5.6 7.1 16.3 4.4 22.9 21.2 27.6 21.4 22.0 13.9 12.4 18.9 25.3 12.2 9.1 30.6 12.5 11.8 8.0 15.7 24.3 16.7 27.0 19.4 13.3 16.4 13.9 15.6 26.3 18.8 12.9 21.0 19.6 14.1 22.4 13.6 17.5 26.2 25.2 17.7 15.7 62.7 37.1 19.9 52.1 10.5 12.3 21.2 43.7 15.3 16.0 13.5 15.7 18.5 20.0 23.2 25.5 20.8 12.6 72.0 13.9 15.6 19.0 26.8 19.0 16.4 14.1 29.1 23.7 31.1 34.0 6.0 1.7 2.0 2.2 2.3 2.8 2.0 2.2 2.2 2.2 2.1 2.6 2.8 1.2 2.6 2.4 2.7 1.7 1.4 5.9 6.0 8.5 6.7 4.9 7.7 7.0 6.8 7.0 6.4 8.2 7.1 29.2 25.6 14.8 13.1 32.7 31.9 26.7 40.0 30.1 10.7 22.7 23.2 41.0 20.0 30.2 31.3 10.4 29.7 43.9 30.3 50.9 27.1 34.8 20.1 34.9 26.3 18.6 29.9 16.2 25.7 33.6 27.9 18.8 26.8 19.7 77.1 27.1 40.0 27.7 8.4 19.7 21.4 48.8 19.7 26.6 58.1 28.3 24.8 23.2 4.7 25.4 15.8 32.0 10.1 16.6 31.1 18.3 19.9 37.7 30.5 25.7 62.8 21.3 16.1 19.7 26.5 28.8 35.5 39.6 33.0 36.4 36.0 37.4 48.3 21.2 23.6 SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 5.1;Kupffer cells: 20.0;Macrophages: 9.5;Microglial cells: 14.0;monocytes: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.5;non-classical monocyte: 24.4" "Group enriched" "Detected in many" 329 "dendritic cells: 21.1;granulocytes: 69.5;monocytes: 51.1" "Cell line enhanced" "Detected in some" "A-431: 4.7;HBEC3-KT: 4.0;HMC-1: 7.8;hTCEpi: 8.5;HUVEC TERT2: 4.3;THP-1: 7.7;TIME: 3.7;U-937: 8.3" "Low region specificity" "Detected in all" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" 5.6 2.4 1.1 12.0 1.2 6.5 1.6 1.3 1.6 1.8 1.8 1.5 0.9 0.9 0.1 1.8 1.6 3.7 1.4 1.1 1.5 1.1 1.8 7.2 7.0 2.7 2.1 0.5 0.7 0.6 0.6 7.5 2.4 0.9 1.7 0.2 1.3 0.6 0.5 0.9 2.0 4.1 1.6 13.1 1.2 0.5 2.7 1.4 0.7 1.8 3.2 3.9 0.9 2.6 4.7 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 7.8 0.0 8.5 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.7 3.7 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 8.3 0.0 3.0 51.1 31.7 0.1 30.4 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.0 69.5 0.0 24.4 0.6 0.0 18.9 1.1 1.2 1.3 1.6 1.1 1.5 2.7 2.1 2.4 1.6 2.7 2.6 0.0 0.0 1.1 0.0 0.5 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.1 1.3 0.0 1.4 0.2 5.1 0.0 0.1 0.0 0.0 20.0 3.3 0.0 0.0 9.5 0.0 14.0 8.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.1 0.7 0.3 0.1 0.0 0.6 SIRPD "dJ576H24.4, PTPNS1L2" ENSG00000125900 "Signal regulatory protein delta" Q9H106 20 1534251-1557705 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 57.8" "Group enriched" "Detected in some" 118 "Early spermatids: 427.6;Late spermatids: 522.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "neutrophil: 37.2" "Group enriched" "Detected in many" 4 "granulocytes: 37.2;monocytes: 21.0" "Cell line enhanced" "Detected in some" "HL-60: 1.5;HMC-1: 1.9;NB-4: 2.6;THP-1: 5.6;U-937: 1.2" "Not detected" "Not detected" HPA042663 Enhanced "Secreted in male reproductive system" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 36: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "HPA042663: AB_2678102" "unprognostic (4.91e-2)" "unprognostic (1.51e-2)" "unprognostic (3.01e-2)" "unprognostic (4.47e-1)" "unprognostic (2.49e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-2)" "unprognostic (2.79e-1)" "unprognostic (3.66e-8)" "unprognostic (2.14e-1)" "unprognostic (3.32e-2)" "unprognostic (9.57e-3)" "unprognostic (2.44e-2)" 0.2 0.1 0.2 2.8 0.1 2.7 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.4 0.1 0.1 0.1 0.1 0.2 1.9 1.1 0.3 0.2 0.3 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.4 0.1 1.5 0.1 57.8 0.1 0.0 0.0 0.0 0.5 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.9 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 21.0 21.5 0.1 13.5 0.2 0.1 0.1 0.2 6.8 0.0 0.1 0.0 37.2 0.0 6.1 4.3 0.3 6.6 0.2 0.1 0.0 0.3 0.1 0.1 0.3 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 427.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 4.0 0.0 522.7 3.4 2.2 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SIRT7 ENSG00000187531 "Sirtuin 7" Q9NRC8 17 81911939-81921323 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 22.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027284, HPA028246, CAB037261, HPA053669" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear speckles" "CAB037261: AB_1079989, HPA027284: , HPA028246: , HPA053669: AB_2682224" "unprognostic (8.15e-3)" "unprognostic (3.24e-2)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.46e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (1.97e-5)" "unprognostic (3.03e-1)" "unprognostic (2.10e-1)" "unprognostic (2.46e-2)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.69e-7)" "unprognostic (4.34e-3)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (2.16e-2)" 8.8 8.0 6.8 7.4 7.3 23.2 8.6 7.5 8.6 12.5 7.4 17.3 12.9 7.0 1.9 42.1 8.0 5.4 6.4 6.9 6.7 11.5 14.2 9.6 11.8 7.6 7.0 6.0 12.8 5.4 6.9 4.2 7.4 9.8 5.8 0.6 14.1 3.7 6.2 22.4 17.1 3.6 7.0 18.7 17.9 13.3 7.6 9.4 7.9 3.7 7.2 10.8 18.0 7.6 26.5 21.7 2.8 9.5 6.9 6.4 17.0 13.1 10.8 15.1 14.1 18.7 20.7 11.8 9.9 7.3 9.6 18.8 10.5 8.1 4.9 10.2 22.9 10.4 10.7 29.7 20.4 13.6 20.5 6.5 25.0 14.5 11.9 6.4 11.3 6.5 11.3 5.8 7.2 20.9 14.6 19.5 6.8 40.6 22.3 9.7 5.5 11.1 14.7 17.4 11.1 14.6 15.0 35.9 17.7 5.0 15.1 32.1 9.0 6.8 14.9 12.9 24.2 9.5 3.2 9.0 16.6 18.4 11.3 4.5 2.6 22.2 2.8 3.8 0.9 4.5 2.1 2.3 1.4 7.0 2.0 0.7 4.4 1.8 3.3 2.1 1.2 1.5 6.8 7.3 7.5 8.6 6.9 6.7 7.6 7.0 7.4 7.0 7.6 7.6 15.2 12.8 12.2 12.4 41.4 38.0 25.8 21.1 28.5 23.4 27.4 19.0 4.4 18.6 18.7 18.4 56.3 31.1 62.8 99.0 9.8 22.4 21.8 28.8 14.0 15.4 20.4 16.0 14.3 13.6 33.2 12.4 152.9 37.0 11.4 20.1 15.0 16.0 26.1 30.3 10.6 34.6 28.5 26.4 33.5 14.1 14.3 29.4 24.9 5.6 47.3 14.7 71.1 6.6 13.8 52.7 74.5 10.1 33.2 29.1 74.7 16.0 29.6 39.1 0.0 12.5 15.5 41.3 37.4 52.4 55.5 49.3 50.8 17.9 44.6 53.9 SLC22A16 "CT2, FLIPT2, OAT6, OKB1" ENSG00000004809 "Solute carrier family 22 member 16" Q86VW1 6 110424687-110476641 "Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 20.5;testis: 21.4" "Group enriched" "Detected in some" 10 "Early spermatids: 34.9;Erythroid cells: 60.4;Late spermatids: 31.8;Spermatocytes: 43.1" "Cancer enriched" "Detected in single" 5 "endometrial cancer: 0.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.7;classical monocyte: 6.9" "Group enriched" "Detected in many" 56 "dendritic cells: 4.0;granulocytes: 5.7;monocytes: 6.9" "Group enriched" "Detected in some" 18 "NB-4: 16.9;REH: 14.6;THP-1: 53.1;U-937: 30.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036902 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA036902: AB_10672274" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (5.11e-3)" "unprognostic (2.19e-3)" "unprognostic (2.70e-4)" "unprognostic (1.45e-1)" "unprognostic (8.15e-2)" "unprognostic (6.93e-2)" "unprognostic (1.48e-2)" "unprognostic (4.98e-2)" "unprognostic (1.02e-3)" "unprognostic (2.49e-1)" "unprognostic (2.61e-6)" "unprognostic (5.78e-4)" "unprognostic (2.72e-2)" "unprognostic (2.74e-2)" "unprognostic (2.65e-2)" 0.3 0.0 0.1 0.6 0.2 20.5 0.1 0.2 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.2 0.2 0.0 0.0 3.8 0.0 0.5 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.8 0.2 0.5 0.0 21.4 0.1 1.2 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 53.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 30.9 0.0 5.7 6.9 1.3 0.0 1.5 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.5 0.1 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.3 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.9 0.4 0.1 0.0 0.0 60.4 0.1 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 1.8 0.5 31.8 1.5 1.1 0.0 0.0 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.3 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 43.1 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 SLC66A1 "FLJ20320, LAAT-1, LAAT1, PQLC2" ENSG00000040487 "Solute carrier family 66 member 1" Q6ZP29 1 19312326-19329300 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 26.9;Extravillous trophoblasts: 17.0;Hofbauer cells: 37.4;Syncytiotrophoblasts: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057810 Approved Supported Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA057810: AB_2683535" "unprognostic (7.84e-3)" "unprognostic (6.56e-2)" "unprognostic (6.54e-2)" "prognostic favorable (3.50e-4)" "unprognostic (3.77e-3)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.64e-5)" "unprognostic (2.61e-1)" "unprognostic (4.47e-2)" "unprognostic (1.04e-1)" "unprognostic (1.42e-3)" "unprognostic (3.82e-2)" "unprognostic (4.70e-3)" "unprognostic (8.64e-2)" "unprognostic (2.07e-1)" "unprognostic (6.56e-2)" "unprognostic (4.46e-2)" 10.7 24.8 12.4 5.6 13.8 13.1 10.7 17.9 14.7 12.9 11.3 11.6 10.7 10.8 9.1 9.8 10.1 6.9 11.3 12.5 13.0 15.2 26.6 10.7 7.9 15.7 13.6 11.0 17.4 7.9 23.2 7.1 14.7 14.2 4.7 12.1 10.5 6.3 14.2 14.1 16.7 5.7 12.1 14.6 14.5 18.6 14.2 4.3 13.5 6.1 5.6 9.9 10.6 15.1 14.6 15.0 13.9 22.4 13.3 12.4 17.6 18.0 24.6 24.7 20.7 22.1 18.0 4.7 23.0 13.3 34.2 10.6 13.7 16.2 11.1 9.9 16.5 3.6 13.4 24.0 37.8 3.1 6.3 20.6 16.7 34.9 11.1 13.8 9.6 8.1 26.8 10.7 24.0 12.8 2.1 10.2 13.3 5.2 13.3 8.1 17.5 8.2 18.9 9.4 17.2 14.3 13.5 9.1 35.5 12.4 15.1 35.8 12.8 20.4 11.8 35.0 16.1 18.4 13.8 2.7 25.1 18.3 17.3 1.3 10.5 10.3 3.7 9.1 2.6 6.0 3.9 3.1 13.7 5.4 1.1 2.3 6.4 4.1 13.8 20.5 3.8 4.5 12.4 13.8 17.9 14.7 12.5 13.0 15.7 13.6 14.7 12.1 14.2 15.1 2.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 26.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 17.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 60.5 0.1 0.0 0.0 0.0 SLC7A10 asc-1 ENSG00000130876 "Solute carrier family 7 member 10" Q9NS82 19 33208664-33225850 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adipose tissue: 31.8;brain: 12.7;breast: 12.7" "Cell type enriched" "Detected in some" 4 "Astrocytes: 40.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 1.9;HHSteC: 1.1;HSkMC: 1.6;THP-1: 3.9;U-2 OS: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041884, HPA057036" Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nucleoli" "HPA041884: AB_10794494, HPA057036: AB_2683317" "unprognostic (1.85e-2)" "unprognostic (1.69e-3)" "unprognostic (2.79e-2)" "unprognostic (1.79e-6)" "unprognostic (1.16e-1)" "unprognostic (2.08e-1)" "unprognostic (1.31e-1)" "unprognostic (4.98e-3)" "unprognostic (4.64e-2)" "unprognostic (1.96e-1)" "unprognostic (3.28e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-2)" "unprognostic (1.34e-3)" "unprognostic (8.91e-2)" "unprognostic (3.47e-1)" "unprognostic (2.18e-2)" 31.8 0.3 7.9 0.1 9.7 0.0 12.7 10.1 11.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.3 9.2 0.5 0.0 0.0 0.2 8.5 12.4 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 0.5 0.8 0.0 0.1 0.2 0.5 0.0 6.0 0.0 0.1 0.5 12.7 0.0 0.5 0.4 0.3 0.3 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 3.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 9.7 10.1 11.1 7.3 9.2 8.5 12.4 8.4 6.0 12.7 5.1 0.1 0.0 0.0 40.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.0 2.4 0.0 9.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 SMAP2 SMAP1L ENSG00000084070 "Small ArfGAP2" Q8WU79 1 40344850-40423326 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 216.3" "Cell type enhanced" "Detected in all" "B-cells: 338.4;dendritic cells: 258.0;Kupffer cells: 284.4;Macrophages: 256.8;monocytes: 291.7;Plasma cells: 224.4;T-cells: 199.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 177.1;THP-1: 302.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021466, HPA024424" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA021466: AB_2239737, HPA024424: AB_1857259" "unprognostic (1.65e-1)" "prognostic favorable (6.55e-4)" "unprognostic (7.17e-2)" "unprognostic (1.40e-3)" "unprognostic (4.32e-1)" "prognostic favorable (5.34e-5)" "prognostic unfavorable (2.53e-4)" "unprognostic (9.05e-2)" "unprognostic (2.27e-1)" "unprognostic (2.24e-1)" "unprognostic (4.00e-3)" "unprognostic (2.65e-1)" "unprognostic (1.02e-2)" "unprognostic (1.88e-2)" "unprognostic (5.45e-2)" "unprognostic (6.23e-2)" "unprognostic (1.24e-1)" 65.3 24.0 44.2 136.7 50.7 80.9 33.3 35.7 54.3 43.9 33.8 33.5 17.5 17.9 14.1 26.2 30.7 46.3 17.2 52.1 48.2 19.2 73.5 58.4 205.8 41.8 41.1 17.1 23.8 27.4 43.9 38.0 42.9 20.0 32.1 48.5 29.5 19.0 30.0 33.3 99.2 40.1 38.3 216.3 41.8 17.0 48.0 158.3 19.2 21.2 199.5 52.2 19.3 47.2 25.1 9.3 22.0 22.2 31.4 60.0 12.2 38.4 34.7 38.9 37.9 11.7 16.8 93.1 18.4 34.4 16.0 10.2 41.1 29.4 53.3 177.1 34.8 51.7 14.2 25.5 28.1 54.3 153.7 51.7 24.3 50.4 21.6 19.1 22.4 71.6 94.9 95.2 47.0 16.8 79.3 51.2 13.4 24.7 84.7 30.3 20.4 96.3 18.9 28.9 37.1 17.1 18.1 46.1 29.9 16.8 14.8 302.3 12.4 42.8 17.6 40.2 29.9 31.3 37.1 75.9 38.8 53.1 28.2 12.4 87.7 102.0 14.5 153.8 18.2 43.7 23.3 22.1 49.3 58.6 32.4 30.1 195.4 31.6 195.8 9.3 35.5 52.1 44.2 50.7 35.7 54.3 52.1 48.2 41.8 41.1 42.9 38.3 48.0 47.2 12.8 25.6 28.4 10.1 338.4 18.0 11.4 8.5 4.0 34.7 17.5 13.6 15.3 30.0 24.5 7.3 22.9 5.5 258.0 11.0 5.9 12.6 12.7 78.2 15.8 18.7 9.5 66.7 75.7 18.7 9.6 17.1 26.0 25.0 28.4 10.4 38.6 66.3 43.5 26.9 52.4 9.8 12.2 284.4 140.1 19.5 5.3 256.8 28.4 89.9 291.7 15.0 129.8 54.8 33.6 17.1 8.9 4.9 224.4 9.6 10.0 9.1 70.2 25.6 32.9 12.8 27.9 15.9 11.6 12.7 17.8 4.1 199.9 14.6 9.5 14.6 SMG5 "EST1B, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5" ENSG00000198952 "SMG5 nonsense mediated mRNA decay factor" Q9UPR3 1 156249224-156282825 "Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072651 Uncertain "Cytoplasmic bodies" No No "Cluster 39: Non-specific - mRNA processing" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cytoplasmic bodies" "HPA072651: AB_2686544" "unprognostic (2.09e-2)" "unprognostic (3.45e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.39e-4)" "unprognostic (3.20e-1)" "unprognostic (4.06e-2)" "prognostic unfavorable (6.70e-9)" "unprognostic (1.28e-1)" "unprognostic (3.21e-3)" "unprognostic (6.90e-2)" "unprognostic (1.82e-2)" "unprognostic (1.71e-2)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (4.28e-1)" "unprognostic (8.77e-2)" "unprognostic (4.26e-2)" 25.2 43.2 44.5 22.0 46.5 46.7 23.7 43.6 46.0 25.6 42.1 35.4 27.3 27.5 24.6 37.3 27.1 18.8 58.8 42.0 42.8 43.4 47.5 32.7 25.8 49.9 48.3 25.7 28.3 46.3 39.0 26.5 46.9 35.2 22.0 35.3 26.8 23.8 62.8 36.4 32.3 28.0 44.4 33.8 33.4 27.7 50.3 29.4 29.9 43.3 24.8 31.2 25.9 53.3 53.4 45.8 54.8 40.9 52.2 29.5 79.0 54.0 48.2 80.0 67.7 116.2 67.4 48.1 61.6 64.8 63.7 62.8 97.3 68.3 51.4 54.5 80.9 55.6 45.8 64.2 67.6 58.8 54.5 37.4 66.7 76.9 81.5 41.2 52.1 70.4 77.0 47.1 56.9 54.5 48.3 47.5 110.9 97.0 94.6 77.2 41.8 51.1 52.1 63.4 73.4 61.1 68.5 100.6 61.8 71.9 86.8 124.3 44.0 55.4 61.6 59.1 79.6 71.7 17.9 89.1 48.8 57.8 71.7 1.6 3.7 5.2 3.8 3.9 3.1 2.9 2.9 2.8 2.4 2.5 2.5 2.7 4.1 3.0 4.2 2.4 2.0 3.6 44.5 46.5 43.6 46.0 42.0 42.8 49.9 48.3 46.9 44.4 50.3 53.3 9.1 16.0 13.4 21.9 16.8 14.7 7.8 7.3 17.6 12.8 14.7 9.8 39.5 18.6 9.6 20.2 33.3 17.8 10.4 44.8 7.9 12.3 2.8 14.1 9.1 12.9 22.7 9.9 23.9 14.5 10.7 9.4 35.2 16.1 12.7 18.4 9.7 21.6 12.4 18.5 21.4 20.3 8.2 14.4 8.6 5.5 8.4 11.1 5.4 19.7 13.5 11.2 7.2 12.1 24.2 17.9 24.2 7.2 17.9 14.3 23.7 15.5 12.8 12.6 6.6 9.2 10.5 8.5 7.8 16.9 12.1 17.1 14.0 11.4 23.6 15.4 SNUPN "RNUT1, SNURPORTIN-1, Snurportin1" ENSG00000169371 "Snurportin 1" O95149 15 75598083-75626469 "Predicted intracellular proteins" Transport RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 137.1;Spermatocytes: 93.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005004 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB005004: AB_425829" "unprognostic (2.37e-2)" "unprognostic (1.54e-1)" "unprognostic (2.36e-2)" "unprognostic (8.73e-2)" "unprognostic (2.25e-1)" "unprognostic (1.18e-1)" "unprognostic (4.76e-2)" "unprognostic (6.74e-2)" "unprognostic (1.35e-1)" "unprognostic (2.14e-1)" "unprognostic (1.99e-3)" "unprognostic (9.07e-2)" "unprognostic (9.97e-2)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (3.12e-1)" "unprognostic (2.14e-2)" 18.2 16.0 21.0 15.5 21.6 13.8 23.5 20.5 26.3 20.4 21.9 18.1 14.9 18.9 20.3 14.3 23.7 13.5 16.4 22.1 20.9 20.1 22.1 14.9 20.1 19.5 20.1 26.3 12.7 21.0 12.1 15.2 20.1 16.5 17.4 13.2 19.8 17.6 34.7 16.7 15.4 24.5 18.7 17.2 15.8 34.3 20.5 22.1 20.9 30.5 21.1 18.0 15.5 21.2 26.1 34.1 30.4 21.6 42.1 46.8 23.2 26.1 38.5 44.2 47.8 25.4 62.6 47.4 35.7 34.0 36.6 29.9 60.3 38.3 34.5 27.3 56.1 56.4 29.3 16.4 40.6 39.4 37.3 44.6 37.3 32.8 41.0 40.1 42.4 36.8 36.8 30.9 45.4 9.0 38.5 38.7 40.6 42.7 19.5 48.7 23.7 46.7 39.7 13.6 28.5 19.9 11.4 38.7 68.9 37.5 33.0 73.8 27.9 35.3 32.8 19.4 23.3 21.9 43.7 69.8 38.7 59.6 47.0 10.3 39.5 12.2 47.4 37.7 57.3 34.7 48.9 45.8 47.7 41.1 63.2 53.0 6.7 36.9 40.1 47.0 42.1 41.0 21.0 21.6 20.5 26.3 22.1 20.9 19.5 20.1 20.1 18.7 20.5 21.2 19.1 12.8 14.5 7.8 13.1 13.3 10.4 30.5 18.2 19.0 18.7 21.5 11.7 14.3 16.8 9.2 12.5 28.7 19.2 10.3 54.8 23.1 137.1 14.9 23.6 14.4 16.2 14.1 9.0 19.3 38.5 25.2 10.7 12.8 12.7 20.4 17.2 18.5 24.7 13.5 8.2 12.4 14.2 17.7 17.3 60.3 31.4 19.1 19.6 7.5 24.2 18.3 25.7 3.0 7.6 14.7 10.5 29.3 9.9 11.5 17.6 34.1 15.1 20.4 19.7 16.6 14.5 93.2 14.6 15.0 10.9 11.9 16.2 27.3 18.1 5.7 SNX13 "KIAA0713, RGS-PX1" ENSG00000071189 "Sorting nexin 13" Q9Y5W8 7 17790761-17940501 "Predicted membrane proteins" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 274.3;Late spermatids: 211.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (7.26e-2)" "unprognostic (7.40e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (9.02e-2)" "unprognostic (3.25e-1)" "unprognostic (2.52e-1)" "unprognostic (4.39e-1)" "unprognostic (1.23e-1)" "unprognostic (2.21e-1)" "unprognostic (7.85e-2)" "unprognostic (5.58e-2)" "prognostic favorable (5.98e-6)" "unprognostic (8.12e-2)" "unprognostic (6.96e-2)" "unprognostic (4.07e-1)" "unprognostic (1.46e-1)" 12.8 12.7 8.7 7.9 9.2 4.8 12.7 10.5 11.1 11.7 8.0 13.0 9.9 13.7 13.0 8.0 9.4 9.2 12.7 9.2 9.6 13.7 9.1 9.5 8.9 8.8 9.3 13.7 9.7 20.9 8.5 14.2 9.0 13.2 13.7 11.2 12.5 9.8 14.2 10.2 9.6 10.1 8.5 10.5 11.6 7.9 9.1 8.3 17.3 17.3 7.2 9.2 10.0 9.5 8.6 4.0 7.5 9.9 19.7 19.0 8.9 8.4 13.3 6.7 8.0 3.5 8.6 9.4 5.6 9.6 14.3 9.1 5.9 7.9 10.9 1.7 6.8 3.3 8.2 4.7 12.4 8.3 6.0 13.7 14.5 6.3 10.7 13.4 9.7 6.6 7.3 7.7 12.1 4.1 6.0 10.5 7.0 11.1 7.1 4.4 7.8 5.1 14.5 13.2 6.5 6.7 7.9 18.0 7.7 14.8 9.6 14.2 9.0 10.3 4.9 13.8 10.1 15.4 6.1 7.3 14.6 5.6 15.1 0.9 0.9 1.2 0.7 1.5 1.1 0.9 0.6 0.5 0.8 0.6 0.8 0.7 2.0 0.9 1.2 0.5 0.4 0.4 8.7 9.2 10.5 11.1 9.2 9.6 8.8 9.3 9.0 8.5 9.1 9.5 29.9 22.4 32.1 65.6 24.6 10.6 14.0 15.6 21.1 19.4 18.4 14.2 41.3 12.8 28.3 12.9 43.8 34.1 20.7 30.1 13.7 13.2 274.3 22.7 30.2 22.9 19.8 24.8 89.7 12.9 14.2 25.6 22.4 17.3 19.6 24.8 35.7 15.4 23.7 16.8 96.0 16.1 22.4 31.4 22.8 211.1 23.6 31.5 5.4 126.5 23.4 18.8 16.5 107.5 94.3 12.3 27.7 17.7 21.2 19.9 18.8 17.3 31.3 25.0 26.3 28.6 24.5 34.2 21.5 20.1 11.9 51.3 18.5 25.7 16.3 24.5 SNX3 Grd19 ENSG00000112335 "Sorting nexin 3" O60493 6 108211222-108261246 "Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" Microphthalmia "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 270000 "Cluster 26: Non-specific - Mitochondria" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "prognostic unfavorable (4.37e-5)" "unprognostic (1.70e-2)" "unprognostic (2.44e-1)" "unprognostic (1.04e-2)" "unprognostic (2.49e-1)" "unprognostic (1.82e-2)" "unprognostic (7.74e-3)" "unprognostic (2.16e-2)" "unprognostic (2.36e-1)" "unprognostic (5.76e-2)" "unprognostic (1.87e-1)" "unprognostic (7.66e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (2.32e-2)" "unprognostic (1.68e-1)" "unprognostic (1.50e-1)" "unprognostic (1.67e-1)" 224.3 220.8 217.3 131.3 220.4 296.3 182.6 216.5 304.6 169.5 208.3 167.6 119.4 137.9 152.8 172.4 144.5 132.0 266.6 224.3 219.6 168.6 199.0 147.3 184.0 214.2 219.8 187.5 123.6 124.4 95.4 199.3 215.8 104.6 112.9 88.3 134.5 119.4 323.0 129.0 125.2 157.0 221.1 145.1 122.0 109.8 218.9 123.4 123.2 285.3 163.6 166.5 147.8 234.9 164.9 98.2 94.9 314.3 505.0 377.9 147.6 241.3 240.3 187.5 231.2 155.0 118.8 138.5 232.8 315.3 328.8 128.6 212.5 207.9 254.6 161.2 136.7 268.1 110.2 182.6 272.9 183.9 175.3 324.4 279.9 180.1 202.1 296.9 312.9 131.0 261.6 161.1 263.1 156.6 70.4 403.7 80.1 199.1 166.2 76.2 229.7 145.4 300.0 225.1 111.0 154.9 155.5 197.7 260.4 212.2 100.6 623.8 235.8 161.0 108.2 218.0 319.7 65.0 90.7 148.9 284.2 332.5 197.2 118.5 75.9 169.1 37.4 70.5 48.2 215.3 43.8 39.5 109.8 181.6 44.6 37.0 48.4 64.5 68.6 132.1 48.8 70.4 217.3 220.4 216.5 304.6 224.3 219.6 214.2 219.8 215.8 221.1 218.9 234.9 329.6 105.8 70.0 39.2 332.6 378.9 328.7 264.3 231.1 44.6 254.0 244.3 395.2 161.5 160.3 191.3 16.7 685.3 219.3 199.1 643.7 307.1 387.8 144.6 161.1 352.6 128.0 611.8 55.7 253.8 581.2 323.0 101.9 120.0 167.1 127.2 275.9 240.6 974.2 43.7 43.1 154.7 189.2 451.6 786.3 496.6 288.6 415.7 368.2 31.9 409.1 325.7 209.1 27.2 39.7 260.1 200.9 266.7 187.1 247.7 321.4 697.8 198.8 53.7 256.4 186.0 304.1 316.5 173.3 354.5 440.8 618.3 181.0 259.4 180.6 337.9 SOWAHD ANKRD58 ENSG00000187808 "Sosondowah ankyrin repeat domain family member D" A6NJG2 X 119758588-119760202 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.1;lymphoid tissue: 7.1;testis: 5.0" "Cell type enhanced" "Detected in some" "B-cells: 12.2;Extravillous trophoblasts: 38.3;Hofbauer cells: 17.5;Proximal enterocytes: 9.1;Rod photoreceptor cells: 8.2;Syncytiotrophoblasts: 9.4" "Cancer enriched" "Detected in many" 6 "testis cancer: 8.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 4.3;NB-4: 2.9;SK-BR-3: 3.2;THP-1: 8.3;U-937: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA065955 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA065955: AB_2685586" "unprognostic (1.78e-2)" "unprognostic (9.37e-2)" "unprognostic (3.10e-2)" "unprognostic (8.88e-2)" "unprognostic (1.67e-1)" "unprognostic (4.38e-2)" "unprognostic (2.03e-1)" "unprognostic (7.20e-2)" "unprognostic (3.45e-2)" "unprognostic (6.07e-2)" "unprognostic (5.80e-2)" "unprognostic (2.41e-2)" "unprognostic (1.04e-5)" "unprognostic (5.82e-2)" "unprognostic (3.14e-2)" "unprognostic (9.22e-2)" "unprognostic (3.74e-3)" 0.3 0.4 0.7 1.8 0.6 2.1 0.2 0.6 0.9 0.2 0.3 1.2 2.1 0.1 0.0 0.2 0.3 0.2 0.2 0.6 0.6 1.1 0.3 1.6 2.5 1.1 0.6 0.3 0.3 0.7 0.1 1.1 0.9 0.2 0.5 0.7 1.7 0.1 0.0 0.3 4.1 0.1 1.0 7.1 1.2 5.0 1.1 0.6 0.1 0.2 1.5 0.3 0.1 1.5 0.4 0.0 0.1 0.1 0.0 0.0 4.3 0.0 0.0 0.4 0.6 0.8 0.1 0.2 0.6 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.0 1.2 0.2 0.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.4 0.0 2.9 0.9 0.8 0.3 2.5 0.1 0.1 0.0 0.1 0.2 0.1 0.9 3.2 0.1 0.3 0.5 8.3 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.0 7.4 0.0 0.0 3.1 1.9 0.0 3.3 0.0 9.1 0.4 0.3 2.0 11.7 1.7 0.9 3.3 0.3 2.9 1.0 0.0 0.7 0.7 0.6 0.6 0.9 0.6 0.6 1.1 0.6 0.9 1.0 1.1 1.5 0.2 0.0 0.0 0.0 12.2 0.0 0.1 0.0 0.0 0.8 0.3 0.5 0.5 1.5 0.0 3.7 0.0 6.1 2.7 3.7 0.0 0.4 0.6 0.1 0.0 0.4 0.0 0.0 0.0 0.4 38.3 0.1 0.5 0.2 0.0 0.2 0.0 0.0 17.5 1.7 0.0 0.9 0.0 5.4 0.6 1.2 0.0 6.5 0.0 0.0 3.4 0.6 1.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 9.1 0.2 0.0 8.2 0.0 0.0 0.2 0.1 0.9 0.1 0.1 9.4 0.5 0.1 2.3 0.0 SP9 ZNF990 ENSG00000217236 "Sp9 transcription factor" P0CG40 2 174334954-174338500 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 3.2" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 11.1" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.2;fHDF/TERT166: 5.5;HEK 293: 2.2;THP-1: 11.6" "Group enriched" "Detected in many" 6 "basal ganglia: 5.8;olfactory bulb: 11.7" "Group enriched" "Detected in many" 4 "basal ganglia: 5.6;olfactory bulb: 21.6" HPA062616 Uncertain Approved Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA062616: AB_2684808" "unprognostic (2.04e-2)" "unprognostic (6.94e-3)" "unprognostic (1.44e-1)" "unprognostic (3.95e-1)" "unprognostic (7.55e-3)" "unprognostic (8.54e-2)" "unprognostic (3.12e-1)" "unprognostic (1.01e-1)" 0.0 0.0 2.5 0.0 2.9 0.0 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.7 1.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.2 7.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.5 0.0 0.1 0.2 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.9 0.0 3.2 0.7 1.6 0.1 0.3 0.1 0.0 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 ST3GAL3 "MRT12, SIAT6" ENSG00000126091 "ST3 beta-galactoside alpha-2,3-sialyltransferase 3" Q11203 1 43705824-43931165 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.0;tongue: 82.9" "Cell type enhanced" "Detected in many" "Astrocytes: 59.7;Excitatory neurons: 94.4;Granulosa cells: 52.5;Inhibitory neurons: 120.1;Microglial cells: 57.1;Oligodendrocyte precursor cells: 66.9;Oligodendrocytes: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051102 Uncertain "Intracellular and membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA051102: AB_2681344" "unprognostic (8.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.22e-1)" "unprognostic (3.20e-1)" "unprognostic (9.72e-2)" "unprognostic (7.01e-2)" "unprognostic (4.39e-2)" "unprognostic (2.33e-2)" "unprognostic (1.38e-3)" "unprognostic (7.00e-2)" "unprognostic (3.68e-3)" "unprognostic (1.67e-2)" "unprognostic (1.30e-1)" "unprognostic (4.35e-1)" "unprognostic (6.60e-2)" 12.9 14.7 28.5 5.0 27.3 11.0 11.0 30.8 32.5 14.6 22.8 19.4 2.6 16.7 9.8 8.3 12.8 6.9 26.1 27.2 29.4 9.9 13.5 8.7 6.1 27.9 29.0 14.9 8.0 6.7 17.8 6.5 29.2 13.2 4.4 24.5 8.3 13.3 88.0 7.0 6.6 13.1 23.2 7.6 9.6 22.6 30.8 4.9 8.4 82.9 3.7 16.7 10.1 28.1 4.3 2.7 23.4 11.0 17.4 21.9 3.0 15.5 30.8 14.1 13.7 2.6 6.6 7.0 8.6 19.0 7.7 3.8 2.8 10.2 15.7 8.7 5.8 15.0 10.6 7.5 14.7 6.6 7.1 12.1 7.4 9.7 21.3 26.1 12.1 18.4 8.8 13.1 25.3 2.7 7.0 11.7 9.2 1.0 8.1 11.4 3.3 6.1 11.0 2.4 9.3 13.8 5.5 2.5 14.1 9.6 3.5 30.3 10.4 8.3 3.9 13.3 15.4 10.4 6.1 6.9 11.7 15.7 15.3 1.7 2.1 1.2 3.3 1.1 2.9 2.2 2.1 2.5 1.5 2.8 3.5 2.6 2.4 2.2 1.9 3.3 2.9 3.3 28.5 27.3 30.8 32.5 27.2 29.4 27.9 29.0 29.2 23.2 30.8 28.1 6.7 6.4 19.3 59.7 6.6 3.3 3.0 4.1 5.7 9.4 4.6 3.3 34.5 1.5 3.8 3.7 0.0 3.1 2.7 2.2 5.9 2.6 19.4 2.4 6.6 7.6 2.4 8.4 94.4 2.4 1.6 9.0 1.5 2.8 24.1 52.5 4.6 8.6 3.1 18.5 120.1 1.4 4.1 2.2 3.1 14.5 3.7 4.5 3.6 57.1 3.6 6.1 5.2 66.9 66.2 2.7 0.2 11.7 4.2 2.2 0.1 6.3 4.9 17.8 19.7 5.8 9.8 8.5 5.1 2.7 1.3 1.0 6.0 15.7 1.7 10.0 STRA8 ENSG00000146857 "Stimulated by retinoic acid 8" Q7Z7C7 7 135231979-135258492 "Predicted intracellular proteins" "Differentiation, DNA replication, Meiosis, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "choroid plexus: 6.6" "Cell type enriched" "Detected in some" 6 "Spermatogonia: 10.8" "Cancer enhanced" "Detected in many" "renal cancer: 2.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.5;THP-1: 2.4;U-266/84: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA078044 Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA078044: " "unprognostic (2.84e-1)" "unprognostic (4.86e-2)" "unprognostic (3.89e-2)" "unprognostic (9.67e-4)" "unprognostic (1.21e-1)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (1.26e-3)" "unprognostic (1.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.45e-1)" "unprognostic (2.69e-1)" 0.1 0.0 0.6 0.0 0.5 0.0 0.0 0.3 0.5 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.3 0.0 0.1 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 2.4 0.1 0.1 0.0 0.0 0.0 0.2 1.5 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.3 0.5 1.0 0.3 0.6 0.5 0.6 0.3 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 10.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 STXBP2 "Hunc18b, UNC18B" ENSG00000076944 "Syntaxin binding protein 2" Q15833 19 7636881-7647873 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 194.2" "Cell type enhanced" "Detected in many" "Kupffer cells: 262.5;Macrophages: 249.1;monocytes: 368.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 248.6;classical monocyte: 471.0;eosinophil: 295.6;intermediate monocyte: 604.8;myeloid DC: 239.7;neutrophil: 356.2;non-classical monocyte: 893.3" "Group enriched" "Detected in all" 6 "dendritic cells: 239.7;granulocytes: 356.2;monocytes: 893.3" "Cell line enhanced" "Detected in many" "HMC-1: 244.8;U-937: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015564, HPA063868" Approved Enhanced Cytosol No No 870000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA015564: AB_1857626, HPA063868: AB_2685136" "unprognostic (1.20e-2)" "unprognostic (6.17e-3)" "unprognostic (2.85e-2)" "prognostic favorable (2.29e-4)" "unprognostic (2.54e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (4.65e-4)" "unprognostic (4.22e-3)" "unprognostic (2.35e-1)" "unprognostic (6.25e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (1.51e-1)" "unprognostic (4.62e-2)" "unprognostic (2.85e-1)" "prognostic favorable (7.68e-4)" "prognostic favorable (5.13e-6)" 24.2 22.8 5.2 65.9 6.3 194.2 24.3 4.8 10.9 22.2 9.3 52.5 67.4 8.4 33.2 73.1 27.7 28.4 7.5 5.1 6.2 62.4 49.0 89.6 51.0 8.3 6.6 5.3 86.7 36.1 29.4 36.3 7.9 52.1 37.0 4.2 79.4 22.8 2.9 52.3 63.9 14.6 6.7 162.2 71.9 74.9 8.8 85.3 52.0 3.0 34.6 34.6 34.8 9.3 113.0 39.1 0.9 0.5 0.0 0.9 75.6 14.2 1.5 2.7 7.4 92.5 69.6 29.6 55.4 11.3 49.5 75.5 4.1 67.5 2.7 124.1 46.9 127.8 49.7 55.8 63.6 83.2 244.8 4.4 67.4 13.4 38.0 0.3 58.5 74.7 81.4 98.5 0.0 70.9 41.2 193.2 28.7 72.7 68.0 41.8 0.3 114.7 55.0 128.1 11.5 0.6 34.0 49.6 2.2 35.6 61.9 212.7 61.7 0.4 21.8 1.5 0.8 108.4 58.6 38.8 1.2 224.8 2.7 248.6 471.0 295.6 69.9 604.8 56.7 47.3 52.7 63.8 239.7 52.2 36.6 44.3 356.2 74.7 893.3 91.5 78.9 306.9 5.2 6.3 4.8 10.9 5.1 6.2 8.3 6.6 7.9 6.7 8.8 9.3 2.1 0.0 7.7 0.7 44.1 23.6 48.2 105.1 18.8 6.0 38.0 22.9 0.9 31.5 68.5 35.0 2.1 97.7 56.2 181.4 33.2 100.3 99.9 32.5 5.4 6.7 59.8 38.3 0.6 118.8 123.2 5.7 150.3 47.6 71.8 34.6 16.4 19.6 168.4 0.0 0.4 108.2 105.8 262.5 46.6 233.5 1.8 249.1 14.2 1.0 368.2 0.9 72.1 0.0 0.0 132.8 152.6 1.9 54.7 49.1 171.7 75.9 42.5 4.0 6.6 1.0 8.6 45.7 20.2 35.3 21.3 153.0 47.7 6.0 79.3 68.7 SVBP "CCDC23, MGC45441" ENSG00000177868 "Small vasohibin binding protein" Q8N300 1 42807052-42817397 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 149.0;Erythroid cells: 135.4;Spermatocytes: 158.0;Spermatogonia: 153.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008507 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Secreted to blood" Yes No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA008507: AB_2072066" "prognostic favorable (6.33e-4)" "unprognostic (2.68e-2)" "unprognostic (2.91e-1)" "unprognostic (4.60e-2)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.15e-2)" "unprognostic (3.35e-3)" "unprognostic (1.59e-2)" "unprognostic (6.73e-3)" "unprognostic (2.16e-1)" "unprognostic (5.37e-3)" "unprognostic (1.17e-3)" "unprognostic (7.07e-2)" "unprognostic (2.44e-3)" "unprognostic (2.31e-3)" 34.7 15.1 36.4 13.7 37.7 43.1 29.9 39.1 49.9 30.9 33.6 29.3 11.6 24.9 26.2 17.7 27.2 15.2 24.7 37.1 38.4 25.6 19.1 17.4 23.0 38.2 37.3 36.3 12.1 22.1 30.6 20.6 37.5 20.3 15.7 22.6 15.9 15.4 28.0 17.7 19.9 19.2 38.2 22.1 19.0 52.9 37.1 48.3 19.0 23.5 23.5 23.9 24.8 40.3 25.9 12.9 75.2 26.9 30.9 48.3 37.2 21.5 18.1 28.8 29.7 22.8 20.2 29.1 23.5 28.6 22.6 18.3 14.3 23.7 35.2 53.6 23.7 54.5 12.1 43.9 25.6 41.3 35.2 31.2 37.4 16.2 15.4 29.7 29.1 56.0 46.2 14.3 35.3 12.0 41.5 50.8 40.8 23.7 14.5 30.9 55.8 19.2 29.9 25.3 45.5 40.4 26.8 14.9 31.7 76.9 11.3 120.1 22.7 25.4 28.1 19.6 35.6 14.9 19.1 20.7 16.1 27.5 24.4 60.5 40.2 76.5 26.8 40.8 23.5 56.4 46.5 32.3 39.2 59.8 42.8 37.2 70.3 37.3 43.8 33.0 115.7 24.7 36.4 37.7 39.1 49.9 37.1 38.4 38.2 37.3 37.5 38.2 37.1 40.3 46.2 9.6 6.3 0.0 25.0 0.0 33.0 0.0 23.9 6.2 33.1 53.1 0.0 28.6 9.3 20.2 2.1 53.8 20.0 19.5 54.8 51.7 149.0 32.2 34.6 32.3 18.2 135.4 0.0 24.5 66.0 36.6 14.3 18.2 11.4 22.8 42.8 45.6 70.4 6.7 0.0 19.6 0.0 51.8 0.0 61.6 42.9 48.4 0.0 0.0 70.2 33.1 29.9 0.0 0.0 43.1 21.7 53.8 16.9 21.9 20.5 43.2 7.3 15.5 59.2 28.1 28.4 158.0 153.8 21.4 0.0 61.6 21.4 24.1 23.6 31.1 SYCP1 "CT8, HOM-TES-14, SCP1" ENSG00000198765 "Synaptonemal complex protein 1" Q15431 1 114854863-114995370 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 70 "testis: 40.2" "Cell type enriched" "Detected in some" 8 "Spermatocytes: 1162.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 98 "THP-1: 17.2" "Region enriched" "Detected in single" 51 "cerebellum: 14.7" "Not detected" "Not detected" HPA021083 Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear bodies, Cytosol" "HPA021083: AB_1857685" "unprognostic (2.91e-1)" "unprognostic (6.89e-3)" "unprognostic (4.87e-1)" "unprognostic (8.74e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.5 0.3 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 56.7 5.3 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 1162.6 32.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TARBP1 "TRM3, TRMT3, TRP-185" ENSG00000059588 "TAR (HIV-1) RNA binding protein 1" Q13395 1 234391313-234479179 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 209.4;Inhibitory neurons: 161.5;Oligodendrocyte precursor cells: 115.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020810, HPA024632" Uncertain Approved "Nuclear speckles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "CAB020810: , HPA024632: AB_1857770" "unprognostic (3.64e-3)" "unprognostic (1.07e-1)" "unprognostic (3.75e-1)" "unprognostic (3.47e-1)" "unprognostic (8.26e-2)" "unprognostic (2.44e-3)" "unprognostic (8.45e-3)" "unprognostic (5.22e-3)" "unprognostic (3.72e-2)" "unprognostic (5.52e-2)" "unprognostic (2.56e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.14e-10)" "unprognostic (5.72e-2)" "unprognostic (1.82e-1)" "unprognostic (4.38e-2)" "unprognostic (4.27e-2)" 4.8 5.2 3.9 7.4 4.0 11.1 9.1 5.5 5.0 4.9 0.1 6.1 6.5 4.9 7.6 6.3 7.6 5.7 3.8 3.7 2.9 5.6 3.9 6.2 10.3 0.4 0.8 2.7 7.7 6.1 6.3 8.3 1.1 7.4 9.0 7.3 9.3 4.5 6.3 7.9 5.8 4.6 0.7 7.5 8.3 4.8 4.3 6.7 6.2 7.1 11.4 3.7 4.2 4.1 18.9 12.9 8.3 9.7 13.6 18.5 17.2 7.9 5.9 10.1 7.4 6.2 12.0 16.3 8.2 6.0 8.7 12.1 9.7 9.9 9.7 16.0 14.9 9.0 14.0 9.1 4.3 39.7 7.6 7.7 8.9 7.3 4.1 7.8 10.5 21.6 11.5 10.2 7.1 3.9 16.5 19.4 17.7 20.1 5.3 28.7 4.9 16.0 6.8 10.8 8.9 10.6 10.8 14.0 12.1 5.5 9.0 39.9 7.1 9.3 1.2 10.4 16.1 27.0 19.0 7.2 6.0 18.3 14.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.1 0.1 0.1 0.0 0.5 0.3 0.0 0.3 0.0 1.1 0.0 0.0 3.9 4.0 5.5 5.0 3.7 2.9 0.4 0.8 1.1 0.7 4.3 4.1 12.4 41.7 22.7 53.8 14.6 6.2 4.1 7.4 7.4 35.1 18.4 18.9 5.8 5.7 13.3 7.3 37.5 20.1 23.3 7.2 1.9 4.7 21.5 13.8 13.6 11.1 11.5 16.4 209.4 5.7 17.6 10.1 16.3 9.9 3.8 13.2 12.1 7.7 9.0 57.2 161.5 12.2 10.2 6.6 9.2 3.6 5.6 11.4 10.6 39.4 8.0 7.7 10.3 115.1 72.3 8.8 6.5 6.0 6.3 6.5 5.8 4.3 27.9 17.1 0.0 12.7 7.8 4.1 8.6 11.5 8.2 11.9 12.8 12.8 19.6 4.8 TASL "CXorf21, FLJ11577" ENSG00000120280 "TLR adaptor interacting with endolysosomal SLC15A4" Q9HAI6 X 30558809-30577766 "Disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.5;lymphoid tissue: 10.9" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "THP-1: 166.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001185 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA001185: AB_1078591" "unprognostic (1.37e-1)" "unprognostic (2.52e-2)" "unprognostic (4.37e-2)" "unprognostic (2.27e-2)" "unprognostic (3.47e-2)" "unprognostic (5.25e-3)" "unprognostic (9.07e-3)" "unprognostic (5.94e-3)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (3.43e-1)" "unprognostic (3.60e-1)" "unprognostic (1.66e-3)" "unprognostic (8.99e-2)" "unprognostic (1.98e-2)" "unprognostic (3.45e-2)" "unprognostic (3.23e-2)" 1.8 1.8 0.6 10.9 0.6 19.5 2.1 0.7 1.0 1.1 1.1 3.5 4.7 0.6 0.4 1.6 0.8 3.9 0.6 0.7 0.6 1.1 2.4 4.7 10.5 1.3 1.1 0.3 0.3 0.7 0.3 2.9 1.3 1.0 3.4 0.2 1.0 0.6 0.1 0.7 3.0 2.2 0.9 9.8 3.6 0.3 1.5 5.8 0.6 0.4 10.2 4.1 0.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.0 0.0 13.8 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 21.5 0.0 0.0 0.0 20.5 0.0 21.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.0 0.0 0.0 0.0 0.0 0.1 15.0 1.6 7.5 0.0 23.9 0.0 8.6 21.9 24.1 1.6 19.8 0.3 23.0 2.0 1.1 25.3 23.6 1.8 1.3 30.6 7.1 44.4 45.9 3.4 8.0 0.6 0.6 0.7 1.0 0.7 0.6 1.3 1.1 1.3 0.9 1.5 2.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 TAX1BP1 "CALCOCO3, TXBP151" ENSG00000106052 "Tax1 binding protein 1" Q86VP1 7 27739331-27844564 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024432 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Cytosol Nucleoplasm "HPA024432: AB_1857783" "unprognostic (1.38e-2)" "unprognostic (5.52e-2)" "unprognostic (3.55e-2)" "unprognostic (2.71e-2)" "unprognostic (2.55e-1)" "unprognostic (9.83e-3)" "unprognostic (1.81e-2)" "unprognostic (2.36e-1)" "unprognostic (4.59e-2)" "unprognostic (6.72e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (3.69e-1)" "prognostic favorable (2.80e-6)" "unprognostic (1.76e-1)" "unprognostic (4.76e-2)" "unprognostic (1.21e-1)" "unprognostic (3.03e-1)" 57.0 107.0 58.0 54.9 61.1 106.6 78.7 62.5 67.6 64.7 71.5 72.3 63.4 63.5 88.2 113.6 78.4 73.1 128.1 56.4 65.7 102.2 80.4 69.5 57.5 61.2 59.9 55.3 69.9 125.2 44.7 104.2 61.3 83.3 79.6 124.3 91.6 79.7 94.4 57.1 67.9 66.0 59.6 66.2 76.3 77.2 63.6 76.7 98.6 89.2 67.8 101.5 52.4 64.5 180.9 98.2 98.1 93.4 151.9 109.9 66.5 131.5 160.9 96.6 120.1 79.8 142.8 38.3 120.9 193.5 166.1 125.0 92.8 86.1 149.8 72.3 48.2 103.6 98.5 160.2 143.0 152.7 117.9 93.7 175.2 112.4 127.9 115.7 105.5 65.3 117.3 113.9 197.5 66.5 67.4 150.1 110.7 234.6 91.0 55.6 105.3 79.1 136.7 200.8 64.9 105.4 184.5 237.8 280.6 187.1 111.1 226.5 114.6 90.5 140.1 113.8 87.8 207.6 154.1 71.2 106.1 283.6 212.3 155.3 81.3 211.8 68.6 100.4 84.4 70.8 81.7 81.2 59.6 62.3 74.5 75.2 163.7 63.4 114.8 55.0 117.1 85.8 58.0 61.1 62.5 67.6 56.4 65.7 61.2 59.9 61.3 59.6 63.6 64.5 111.3 214.7 199.3 58.1 122.8 183.3 269.4 220.7 100.7 375.3 161.6 98.2 595.7 134.4 268.4 128.8 95.9 154.7 178.2 209.3 412.8 211.5 124.3 342.9 128.2 142.9 140.0 160.4 107.4 262.9 105.6 156.7 118.3 245.9 148.8 101.3 78.9 106.3 123.1 159.9 107.0 162.1 242.1 144.7 107.3 94.2 116.8 191.4 113.8 86.2 260.0 189.8 141.1 82.0 105.7 301.4 166.1 148.6 157.4 291.0 146.0 323.4 546.6 147.6 105.2 126.6 202.7 221.8 137.5 121.7 191.9 621.4 166.1 197.0 140.3 393.3 TBX4 ENSG00000121075 "T-box transcription factor 4" P57082 17 61452404-61485110 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 32.3;placenta: 21.0;prostate: 9.0" "Group enriched" "Detected in some" 8 "Early spermatids: 6.2;Late spermatids: 14.6" "Cancer enhanced" "Detected in some" "lung cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 2.9;Hep G2: 1.2;OE19: 1.2;THP-1: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB032413, HPA044457" Uncertain Approved Vesicles NA NA "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB032413: AB_2200705, HPA044457: AB_2678948" "unprognostic (1.03e-2)" "unprognostic (2.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.63e-3)" "unprognostic (6.07e-2)" "unprognostic (3.80e-2)" "unprognostic (1.25e-2)" "unprognostic (4.14e-2)" "unprognostic (7.77e-3)" "unprognostic (7.41e-2)" "unprognostic (6.83e-2)" "unprognostic (1.38e-1)" "unprognostic (1.46e-8)" "unprognostic (1.92e-1)" "unprognostic (4.41e-2)" "unprognostic (6.15e-2)" "unprognostic (5.39e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.0 0.1 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 32.3 0.1 0.1 0.1 0.0 0.3 0.0 0.0 21.0 0.1 9.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 7.2 0.4 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 2.9 0.3 0.2 0.2 1.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 1.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.3 0.1 0.0 5.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TCF23 "bHLHa24, OUT" ENSG00000163792 "Transcription factor 23" Q7RTU1 2 27149004-27156974 "Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "endometrium 1: 51.2;fallopian tube: 24.6;ovary: 18.5;smooth muscle: 20.4" "Cell type enhanced" "Detected in some" "Leydig cells: 10.5;Peritubular cells: 29.0;Sertoli cells: 52.6" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 1.6" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 12 "THP-1: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA044596 Approved "Nuclear speckles" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "HPA044596: AB_10797258" "unprognostic (1.04e-1)" "unprognostic (2.47e-3)" "unprognostic (1.70e-2)" "unprognostic (4.21e-2)" "unprognostic (3.65e-2)" "unprognostic (2.68e-2)" "unprognostic (1.70e-2)" "unprognostic (4.07e-2)" "unprognostic (3.21e-1)" "unprognostic (1.74e-2)" "unprognostic (4.08e-2)" "unprognostic (8.58e-2)" "unprognostic (2.41e-5)" "unprognostic (7.58e-3)" "unprognostic (3.01e-1)" "unprognostic (8.58e-4)" "unprognostic (2.64e-2)" 0.4 0.0 0.2 0.0 0.2 0.2 0.0 0.5 0.4 4.6 0.2 0.2 0.1 51.2 5.8 0.0 24.6 0.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.1 18.5 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.5 0.2 0.1 0.1 20.4 0.0 2.3 0.1 2.6 0.2 0.0 0.0 0.0 0.0 0.2 2.9 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.2 0.2 0.1 0.2 0.3 0.3 0.2 0.0 0.4 0.3 0.2 1.1 0.3 0.1 0.4 0.1 0.0 0.2 0.2 0.5 0.4 0.3 0.2 0.1 0.1 0.3 0.0 0.2 0.5 0.1 0.0 2.2 0.0 0.3 0.0 0.6 0.0 0.0 0.4 0.3 0.3 0.7 0.0 0.6 0.0 2.1 0.0 0.2 0.1 0.0 0.0 1.7 0.2 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 1.3 0.1 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 10.5 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.7 0.0 0.1 0.0 0.6 52.6 1.0 1.5 0.3 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.6 TENT5A "C6orf37, FAM46A, FLJ20037" ENSG00000112773 "Terminal nucleotidyltransferase 5A" Q96IP4 6 81491439-81752774 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 225.9;salivary gland: 104.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 73.1;Endometrial stromal cells: 70.6;Extravillous trophoblasts: 115.4;Glandular and luminal cells: 176.7;Syncytiotrophoblasts: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 81.9;HeLa: 86.1;HL-60: 95.6;THP-1: 162.0;U-937: 72.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051067, HPA067140" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA051067: , HPA067140: AB_2685788" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (5.39e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (2.62e-3)" "unprognostic (5.93e-2)" "unprognostic (2.48e-2)" "unprognostic (2.53e-1)" "unprognostic (1.03e-1)" "unprognostic (1.40e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (7.18e-2)" "unprognostic (6.38e-2)" "unprognostic (9.25e-2)" "unprognostic (9.66e-2)" 13.5 21.3 4.3 7.9 4.6 225.9 12.2 9.0 5.8 21.3 9.9 17.2 16.4 10.2 19.7 4.4 12.0 32.3 21.7 4.0 14.0 6.4 35.9 9.1 5.2 7.8 7.1 23.6 8.3 9.4 17.4 18.7 6.1 9.9 16.9 8.7 104.4 24.8 2.1 18.7 22.2 11.1 5.0 9.9 37.8 3.7 6.7 2.9 8.8 5.1 4.3 16.6 8.8 5.3 3.5 5.0 3.3 0.2 67.9 29.8 6.2 27.0 19.2 15.7 23.5 51.0 2.6 0.3 1.0 81.9 10.0 2.9 2.4 4.2 11.5 0.0 6.2 0.1 86.1 8.0 21.2 95.6 7.1 13.2 2.4 12.3 2.1 51.2 2.0 0.8 1.4 0.0 10.6 14.7 0.0 67.2 0.9 29.2 3.8 0.0 28.8 0.1 2.1 6.2 3.3 4.4 12.1 5.2 8.3 9.9 1.2 162.0 4.5 17.9 3.8 7.6 7.6 0.4 0.3 0.3 25.3 72.7 7.8 37.3 29.9 46.3 11.5 29.6 6.8 18.2 4.3 5.7 24.2 21.0 8.1 8.0 13.8 16.9 47.3 8.5 5.6 14.0 4.3 4.6 9.0 5.8 4.0 14.0 7.8 7.1 6.1 5.0 6.7 5.3 22.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 40.8 44.2 0.0 0.0 0.0 5.5 0.0 39.9 43.1 0.0 3.9 30.5 0.0 73.1 70.6 2.9 0.0 0.0 0.0 23.4 115.4 32.7 0.0 176.7 0.0 40.9 0.0 0.0 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 9.8 0.0 0.0 0.0 0.0 26.7 0.0 0.0 5.9 0.0 0.0 3.6 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 162.0 9.4 12.6 0.0 0.0 TEX101 "CT131, MGC4766, SGRG, SPATA44, TES101RP" ENSG00000131126 "Testis expressed 101" Q9BY14 19 43401496-43418597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 117.7" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 909.7" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 5 "cerebral cortex: 21.5" "Immune cell enriched" "Detected in single" 557 "basophil: 55.7" "Lineage enriched" "Detected in single" 557 "granulocytes: 55.7" "Cell line enhanced" "Detected in single" "THP-1: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA041915, HPA042513" Enhanced "Secreted in male reproductive system" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA041915: AB_10795268, HPA042513: AB_10795507" "unprognostic (2.50e-2)" "unprognostic (5.67e-4)" "unprognostic (2.64e-1)" "unprognostic (6.89e-2)" "unprognostic (1.87e-1)" "unprognostic (5.78e-4)" "unprognostic (1.70e-1)" "unprognostic (2.84e-2)" "unprognostic (6.54e-2)" "unprognostic (4.06e-1)" "unprognostic (2.49e-2)" "unprognostic (1.67e-7)" "unprognostic (8.83e-2)" "unprognostic (2.24e-1)" "unprognostic (7.49e-2)" "unprognostic (7.04e-2)" 0.1 0.4 0.3 0.3 0.3 0.1 0.2 0.3 21.5 0.5 0.2 0.5 0.4 0.4 0.2 1.3 0.3 0.2 0.5 2.6 0.2 0.2 0.5 0.2 0.2 4.3 0.2 0.5 1.6 0.1 0.0 0.2 2.0 0.3 0.5 0.0 1.1 0.2 0.6 1.5 0.5 0.3 1.1 0.1 0.2 117.7 0.3 1.0 0.1 0.0 1.3 0.1 1.0 0.4 0.2 0.0 0.3 0.1 0.2 0.6 0.1 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.4 0.3 0.1 0.1 0.2 0.1 0.3 0.0 0.1 0.4 0.1 0.5 0.1 0.2 0.3 0.4 0.0 0.2 0.2 0.4 0.2 0.1 0.2 0.3 0.0 0.1 0.2 0.1 0.2 0.1 0.7 0.0 0.2 0.5 0.0 0.2 0.0 0.1 0.2 0.6 0.1 0.0 1.3 0.1 0.2 0.1 0.1 0.3 0.2 0.3 0.1 0.2 0.1 0.1 55.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 21.5 2.6 0.2 4.3 0.2 2.0 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.2 0.1 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 10.2 0.0 0.0 31.5 6.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 909.7 151.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 THBS4 ENSG00000113296 "Thrombospondin 4" P35443 5 79991311-80083287 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Tissue remodeling, Unfolded protein response" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 216.7;heart muscle: 167.9;smooth muscle: 251.4;tongue: 214.6" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 493.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 46 "eosinophil: 4.5" "Lineage enriched" "Detected in single" 46 "granulocytes: 4.5" "Cell line enhanced" "Detected in some" "AF22: 3.1;THP-1: 7.0;U-2 OS: 2.8;U-266/70: 2.6" "Region enriched" "Detected in many" 8 "white matter: 85.7" "Region enriched" "Detected in many" 27 "spinal cord: 89.3" "CAB004597, HPA042426" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 510000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB004597: AB_628352, HPA042426: AB_2677992" "unprognostic (1.41e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-3)" "unprognostic (3.64e-2)" "unprognostic (9.94e-2)" "unprognostic (8.10e-2)" "unprognostic (5.64e-2)" "unprognostic (7.12e-2)" "unprognostic (1.66e-1)" "unprognostic (2.25e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-3)" "unprognostic (2.74e-2)" "unprognostic (3.98e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (3.33e-4)" 216.7 1.2 15.4 5.2 19.6 10.6 26.8 13.8 13.0 2.1 5.0 58.1 2.2 26.8 1.6 6.0 2.5 10.4 167.9 12.2 24.5 0.7 0.3 1.3 1.1 22.3 25.3 4.1 22.8 35.7 14.3 0.2 19.9 9.0 8.7 7.5 46.5 5.7 77.2 2.9 3.3 251.4 21.7 0.3 8.6 8.7 28.0 3.6 27.0 214.6 4.0 3.5 5.8 20.0 0.1 0.0 3.1 0.2 0.2 1.3 0.3 0.1 0.1 0.9 0.3 0.1 0.4 0.1 0.1 0.2 0.8 0.1 0.1 0.4 0.8 0.1 0.4 0.3 0.0 0.2 1.7 0.0 0.0 0.9 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 2.4 0.0 0.0 0.0 0.9 0.0 0.2 0.0 2.5 0.7 0.0 0.0 0.2 1.3 0.0 7.0 0.0 0.0 2.8 0.2 0.2 2.6 0.1 0.4 1.1 2.2 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 19.6 13.8 13.0 12.2 24.5 22.3 25.3 19.9 21.7 28.0 20.0 57.0 0.0 1.1 37.2 0.7 0.3 0.1 0.2 2.2 1.3 0.8 1.8 9.1 0.0 0.7 3.7 56.3 0.1 0.5 0.0 0.0 0.2 40.8 0.3 0.8 9.4 9.0 0.0 9.7 0.0 0.0 84.2 0.5 0.3 0.0 5.9 0.4 0.2 0.1 1.7 12.7 0.0 0.0 0.0 0.3 7.2 0.9 2.7 1.8 6.5 0.0 2.2 0.0 60.3 24.0 0.0 0.0 43.6 0.3 1.0 0.0 0.8 0.2 1.9 493.0 78.9 116.9 14.5 2.1 0.6 1.0 0.0 2.1 1.2 0.0 0.0 THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.5" "Cell type enhanced" "Detected in many" "Astrocytes: 150.5;Bipolar cells: 183.8;Horizontal cells: 208.6;Inhibitory neurons: 494.3;Oligodendrocyte precursor cells: 262.4" "Cancer enhanced" "Detected in many" "renal cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 54 "basophil: 5.3" "Lineage enriched" "Detected in single" 54 "granulocytes: 5.3" "Cell line enhanced" "Detected in some" "A549: 10.3;HUVEC TERT2: 6.7;REH: 7.1;SH-SY5Y: 10.2;THP-1: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" NA NA 6100000 "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA000923: AB_1080271" "unprognostic (3.01e-1)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.44e-1)" "unprognostic (9.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "prognostic favorable (2.24e-6)" "unprognostic (2.13e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" 2.4 0.7 2.9 0.7 2.3 0.0 2.1 3.2 4.4 3.3 0.0 1.0 0.3 2.8 0.8 0.5 2.1 2.6 0.7 4.2 3.5 7.5 0.6 1.1 0.3 2.8 4.9 2.5 0.4 1.2 1.6 4.1 2.5 3.4 0.7 5.0 0.5 2.1 0.2 0.5 0.5 2.4 3.4 0.9 0.5 0.8 4.8 0.2 1.9 1.2 0.2 1.8 1.7 2.4 0.0 10.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 1.6 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 7.1 0.0 0.0 0.3 0.1 0.7 10.2 0.0 0.3 0.0 1.6 0.1 19.2 3.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 3.2 4.4 4.2 3.5 2.8 4.9 2.5 3.4 4.8 2.4 46.9 22.4 8.2 150.5 0.0 2.7 1.4 0.0 1.2 183.8 0.8 0.5 1.5 21.5 2.8 55.2 112.6 23.5 0.1 0.4 7.9 7.0 1.2 4.9 22.4 42.6 41.7 0.0 56.6 2.2 4.3 8.1 0.5 18.8 0.0 6.1 28.2 1.3 2.2 208.6 494.3 0.8 0.0 1.5 2.9 0.5 24.2 0.5 12.4 105.9 0.0 20.7 0.0 262.4 5.4 5.5 6.8 1.5 0.1 7.7 0.1 8.8 0.1 9.3 0.0 10.6 5.0 1.6 1.1 0.6 2.4 51.9 0.8 21.5 1.2 1.1 TIFAB ENSG00000255833 "TIFA inhibitor" Q6ZNK6 5 135444226-135452351 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.6" "Cell type enhanced" "Detected in some" "dendritic cells: 8.0;Early spermatids: 4.2;Hofbauer cells: 4.0;Langerhans cells: 17.6;Late spermatids: 9.2;monocytes: 4.6" "Cancer enriched" "Detected in single" 4 "testis cancer: 0.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "myeloid DC: 4.5;plasmacytoid DC: 13.9" "Lineage enriched" "Detected in many" 11 "dendritic cells: 13.9" "Cell line enriched" "Detected in some" 5 "THP-1: 9.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049372 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA049372: AB_2680733" "unprognostic (1.33e-2)" "unprognostic (1.09e-2)" "unprognostic (1.63e-2)" "unprognostic (1.71e-2)" "unprognostic (1.35e-1)" "unprognostic (1.98e-5)" "unprognostic (3.87e-1)" "unprognostic (3.25e-3)" "unprognostic (5.29e-2)" "unprognostic (1.09e-2)" "unprognostic (6.08e-2)" "unprognostic (1.96e-1)" "unprognostic (1.01e-2)" "unprognostic (2.31e-1)" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (9.01e-2)" 0.1 0.0 0.0 3.7 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.9 1.0 0.1 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.5 5.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.2 0.0 0.0 0.9 1.0 0.2 0.0 2.6 0.7 0.3 0.0 1.9 0.0 0.0 4.9 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 17.6 9.2 0.0 2.2 0.0 0.0 4.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TKTL1 "TKR, TKT2" ENSG00000007350 "Transketolase like 1" P51854 X 154295795-154330350 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "testis: 127.1" "Group enriched" "Detected in some" 7 "Spermatocytes: 166.9;Spermatogonia: 491.5" "Cancer enriched" "Detected in many" 8 "testis cancer: 44.2" "Group enriched" "Detected in some" 5 "cerebral cortex: 4.3;medulla oblongata: 1.7" "Group enriched" "Detected in many" 5 "eosinophil: 60.9;gdT-cell: 24.4" "Group enriched" "Detected in many" 5 "granulocytes: 60.9;T-cells: 24.4" "Cell line enriched" "Detected in some" 163 "THP-1: 495.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "white matter: 1.2" "HPA000505, HPA029155, CAB032191" Enhanced Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 74: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "CAB032191: , HPA000505: AB_1858022, HPA029155: AB_10603134" "unprognostic (2.69e-1)" "unprognostic (1.92e-1)" "unprognostic (1.98e-1)" "unprognostic (5.80e-3)" "unprognostic (2.43e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-2)" "unprognostic (1.00e-1)" "unprognostic (2.10e-2)" "unprognostic (1.61e-1)" "unprognostic (1.98e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.34e-2)" "unprognostic (3.90e-2)" "unprognostic (5.04e-2)" "unprognostic (2.38e-1)" 0.3 0.1 0.3 0.4 0.4 0.9 0.2 0.2 4.3 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 3.8 0.3 0.3 0.3 0.2 1.0 0.4 1.7 0.2 0.1 0.0 0.0 0.9 0.3 0.6 0.1 0.0 2.2 0.0 0.0 0.3 0.2 0.1 0.1 0.5 0.7 0.0 127.1 0.5 0.4 0.1 0.5 0.1 0.1 0.1 0.5 0.3 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.6 0.0 0.0 495.2 0.0 0.0 0.0 0.1 0.2 0.0 3.0 2.7 0.0 0.0 0.4 1.6 0.1 60.9 24.4 0.4 3.5 0.1 2.9 2.2 0.0 0.1 6.0 5.4 1.0 7.8 0.3 0.2 3.5 5.8 0.3 0.4 0.2 4.3 0.3 0.3 1.7 0.2 0.6 0.5 0.5 0.5 0.2 0.0 0.0 0.7 0.5 0.3 0.0 0.0 0.6 0.3 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 44.8 0.0 0.1 0.7 0.0 0.4 0.4 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.1 0.2 25.2 0.4 0.0 0.0 0.3 3.7 22.5 4.1 1.9 0.0 1.0 0.6 6.0 20.6 1.0 0.1 0.0 0.0 1.9 1.3 0.0 0.0 0.1 0.0 1.0 26.3 1.4 1.6 166.9 491.5 0.1 0.1 0.0 4.1 0.1 0.0 0.0 TLR2 "CD282, TIL4" ENSG00000137462 "Toll like receptor 2" O60603 4 153684070-153706260 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 69.9;lymphoid tissue: 51.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 77.3;Kupffer cells: 117.2;Langerhans cells: 35.7;Macrophages: 101.8;Microglial cells: 33.7;monocytes: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 199.6;intermediate monocyte: 178.9;myeloid DC: 121.3;neutrophil: 457.8;non-classical monocyte: 121.5" "Group enriched" "Detected in all" 49 "dendritic cells: 121.3;granulocytes: 457.8;monocytes: 199.6" "Cell line enhanced" "Detected in some" "HL-60: 11.6;HSkMC: 12.5;hTCEpi: 12.7;NB-4: 11.4;RPTEC TERT1: 13.3;RT4: 16.3;THP-1: 62.0;U-937: 11.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060231, HPA071546" Supported Nucleoplasm,Mitochondria No NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Mitochondria" "HPA060231: , HPA071546: " "unprognostic (4.15e-1)" "unprognostic (3.29e-2)" "unprognostic (5.32e-2)" "unprognostic (1.52e-2)" "unprognostic (3.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.39e-2)" "unprognostic (4.24e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-2)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.87e-2)" "unprognostic (3.80e-3)" "unprognostic (1.42e-1)" "unprognostic (5.93e-3)" 26.8 11.8 4.3 51.7 4.4 69.9 12.5 4.6 7.5 7.9 7.6 4.6 3.9 3.3 11.8 5.4 8.2 16.3 6.1 4.0 5.3 5.1 11.3 39.9 8.8 9.5 5.9 2.5 8.8 3.4 4.0 11.4 7.9 4.7 3.3 1.5 17.2 12.3 1.7 3.5 4.9 11.7 7.1 35.9 5.2 1.9 7.4 3.6 3.4 3.7 15.4 23.6 4.0 10.1 7.1 0.1 0.3 0.0 1.0 2.9 0.0 0.0 0.5 0.5 0.8 3.3 0.4 0.0 0.8 0.0 0.0 6.4 0.6 0.4 0.3 0.1 0.1 0.2 0.0 0.8 0.1 11.6 0.9 12.5 12.7 0.0 0.1 0.8 0.0 0.0 0.0 0.1 0.1 0.1 0.0 11.4 0.7 0.0 2.7 0.3 0.0 0.0 13.3 16.3 0.0 0.3 0.7 0.1 3.3 0.4 0.0 62.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 11.3 1.7 48.4 199.6 1.8 0.3 178.9 0.5 0.4 1.1 0.3 121.3 1.2 1.3 0.2 457.8 5.3 121.5 1.1 0.2 76.2 4.3 4.4 4.6 7.5 4.0 5.3 9.5 5.9 7.9 7.1 7.4 10.1 1.7 6.4 77.3 0.7 1.1 1.1 1.2 18.4 1.2 0.0 9.7 2.2 1.3 2.8 19.5 3.7 0.0 0.2 0.6 0.2 0.0 5.0 0.3 1.6 0.5 2.6 0.0 3.6 0.1 3.8 0.2 1.9 2.6 4.9 3.8 0.5 1.4 1.8 17.4 0.0 0.5 0.3 0.0 117.2 35.7 1.3 0.6 101.8 1.8 33.7 68.4 0.4 1.0 1.0 0.1 3.1 0.0 0.4 1.4 3.4 1.5 1.0 7.5 0.3 13.1 0.6 5.1 0.2 1.0 1.9 1.1 0.1 2.3 0.5 0.5 2.0 TM9SF2 P76 ENSG00000125304 "Transmembrane 9 superfamily member 2" Q99805 13 99446311-99564048 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005657 Supported NA NA 2100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA005657: AB_1080303" "unprognostic (9.77e-3)" "unprognostic (3.51e-2)" "unprognostic (2.85e-2)" "unprognostic (1.09e-2)" "unprognostic (3.76e-1)" "prognostic unfavorable (6.40e-4)" "unprognostic (5.96e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "unprognostic (2.99e-2)" "unprognostic (1.66e-1)" "unprognostic (5.19e-2)" "prognostic favorable (5.21e-7)" "unprognostic (6.49e-2)" "unprognostic (8.55e-2)" "unprognostic (2.20e-2)" "unprognostic (2.21e-1)" 66.6 67.2 34.4 66.7 37.4 64.6 90.6 35.9 41.4 100.2 62.5 115.8 119.4 63.6 119.0 56.1 76.6 73.6 51.0 35.8 40.3 108.4 169.4 78.6 62.1 35.9 35.1 53.2 90.2 126.8 41.5 98.2 36.6 97.8 123.7 41.9 109.6 73.2 36.3 56.6 119.3 65.7 39.8 62.4 104.1 59.6 36.9 49.7 121.2 48.3 71.3 90.0 44.4 44.9 187.3 56.7 75.8 107.8 223.2 134.8 108.2 124.1 154.5 86.6 134.8 93.1 234.7 72.1 100.0 150.1 88.4 183.1 81.1 108.7 117.8 80.8 57.8 89.6 90.9 100.2 118.0 235.8 100.0 106.2 132.4 75.1 76.8 133.2 110.4 72.8 90.7 70.0 103.0 62.8 59.1 91.9 66.3 335.7 70.0 49.3 61.0 78.7 178.9 137.3 71.7 87.5 71.7 285.6 94.8 145.5 174.0 280.5 109.1 69.6 50.7 70.5 77.8 96.6 120.8 29.0 163.8 120.0 103.0 192.4 156.4 174.9 57.7 180.5 72.8 86.9 68.4 65.3 139.6 60.1 62.8 58.4 251.3 76.0 182.1 159.6 109.6 178.1 34.4 37.4 35.9 41.4 35.8 40.3 35.9 35.1 36.6 39.8 36.9 44.9 68.9 83.3 76.3 29.0 72.5 40.9 57.3 132.8 48.9 20.6 82.9 40.5 44.0 70.1 170.7 86.5 18.8 99.3 94.5 141.1 11.7 98.6 149.2 101.0 75.6 65.4 83.0 47.9 36.6 102.7 122.8 74.6 89.2 93.9 54.5 35.2 87.4 172.9 116.0 21.9 44.4 167.9 128.1 137.6 57.2 41.8 50.1 100.7 72.9 44.0 97.4 42.7 42.2 34.2 44.8 83.4 116.7 52.3 143.1 69.0 123.5 70.8 187.7 25.3 19.7 44.1 104.1 109.7 56.3 69.8 52.1 171.4 53.2 43.2 119.4 104.0 TMEM104 "FLJ00021, FLJ20255" ENSG00000109066 "Transmembrane protein 104" Q8NE00 17 74776499-74839753 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044330 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Golgi apparatus" "HPA044330: AB_10960543" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (2.70e-1)" "unprognostic (1.71e-2)" "unprognostic (5.95e-2)" "unprognostic (4.99e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (7.46e-2)" "unprognostic (2.86e-2)" "unprognostic (4.75e-1)" "prognostic favorable (1.97e-5)" "unprognostic (8.14e-2)" "unprognostic (6.17e-2)" "unprognostic (8.46e-2)" "unprognostic (7.95e-2)" "unprognostic (2.82e-3)" "unprognostic (1.00e-2)" 6.5 10.7 7.0 5.6 9.1 8.4 5.3 9.2 7.9 3.9 5.6 5.0 3.5 4.7 3.8 6.6 4.2 3.4 7.2 6.5 6.8 7.7 14.9 7.8 4.5 10.4 9.3 3.8 8.1 8.1 9.9 5.0 9.8 5.5 2.9 2.0 7.5 3.8 5.4 5.2 5.3 4.2 8.2 7.0 6.1 8.4 9.3 4.2 7.8 3.8 4.4 5.1 4.2 10.8 10.8 26.0 13.4 15.4 18.9 11.7 8.1 18.2 18.1 22.8 25.1 21.1 11.2 5.6 5.8 20.9 23.4 12.0 13.8 10.2 12.0 4.2 19.5 14.1 10.5 15.0 13.8 23.5 12.6 9.3 10.9 23.1 5.0 6.8 16.5 13.6 8.4 8.5 15.6 10.3 14.1 9.3 7.5 14.2 20.6 8.7 21.3 9.4 9.9 9.3 11.4 15.1 10.1 12.9 13.6 10.0 16.5 35.8 13.2 48.0 12.1 18.4 24.0 5.9 5.5 6.5 18.5 24.0 18.6 1.4 5.0 3.7 4.7 4.1 2.4 3.3 4.5 4.4 5.3 0.8 3.7 2.6 2.1 2.8 4.6 5.5 5.0 3.6 7.0 9.1 9.2 7.9 6.5 6.8 10.4 9.3 9.8 8.2 9.3 10.8 2.3 6.4 5.8 7.8 2.2 2.5 1.1 3.4 0.6 2.7 5.6 3.3 49.5 8.6 4.6 5.5 2.1 4.1 5.2 6.0 0.0 5.0 3.0 3.3 2.7 4.8 8.3 1.7 5.6 5.6 4.3 4.6 5.6 6.4 1.3 3.2 2.9 14.2 13.3 0.0 4.4 4.7 4.1 7.3 3.8 3.5 2.8 9.5 0.0 4.7 4.7 4.1 3.1 4.0 11.1 6.2 3.4 2.2 8.2 2.5 3.4 1.9 2.0 3.1 0.0 3.3 4.2 4.4 3.8 2.8 2.3 3.8 4.3 2.5 3.6 1.6 TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;prostate: 6.6" "Cell type enhanced" "Detected in some" "granulocytes: 1.3;Hofbauer cells: 2.8" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.6" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;monocytes: 1.1" "Cell line enhanced" "Detected in some" "AF22: 6.0;SCLC-21H: 14.2;THP-1: 11.9;U-937: 9.8" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" 0.3 0.6 6.4 0.9 7.5 1.0 0.7 3.5 7.6 0.2 1.5 0.2 0.2 0.3 0.9 0.3 0.3 0.2 1.2 8.7 3.9 0.3 0.1 0.3 0.1 3.8 3.3 0.2 1.1 0.1 1.6 0.7 3.3 6.6 0.2 1.3 0.4 0.2 1.3 0.5 0.2 0.3 3.6 0.7 0.2 1.9 4.9 0.1 0.1 0.4 0.1 0.3 0.2 5.1 0.0 0.0 6.0 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.7 0.0 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.1 0.3 0.0 0.8 3.2 2.1 0.0 0.1 0.2 3.0 0.0 0.3 0.1 14.2 2.1 0.0 0.0 0.3 0.8 0.0 11.9 0.6 0.6 0.2 0.2 0.0 0.2 0.4 0.9 0.0 9.8 0.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 6.4 7.5 3.5 7.6 8.7 3.9 3.8 3.3 3.3 3.6 4.9 5.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 1.3 0.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 70.4;Kupffer cells: 65.4;Macrophages: 35.8;monocytes: 34.7;NK-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 29.8;HL-60: 17.6;HMC-1: 44.1;NB-4: 25.2;THP-1: 95.2;U-937: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" 4.7 4.3 4.9 19.6 5.4 6.1 3.4 5.1 7.5 2.3 5.7 4.5 5.3 1.5 1.4 2.5 2.2 5.5 2.3 4.7 5.2 2.0 5.6 10.8 32.0 6.5 5.7 1.0 1.4 1.2 1.2 6.9 7.0 2.1 6.1 0.9 2.6 1.8 0.8 3.8 7.6 5.4 6.4 39.2 3.4 0.8 6.3 19.2 1.3 2.2 17.7 7.8 1.4 8.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 29.8 0.4 0.0 0.0 17.6 44.1 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.1 0.1 0.0 0.1 0.4 25.2 0.0 0.0 0.1 5.3 0.1 4.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 95.2 2.5 0.2 0.1 0.1 0.2 0.3 0.0 1.9 0.1 37.8 0.1 317.0 238.8 246.7 103.2 220.2 101.9 78.3 125.7 105.2 265.4 83.2 189.5 137.3 292.3 232.9 210.6 63.0 155.7 249.5 4.9 5.4 5.1 7.5 4.7 5.2 6.5 5.7 7.0 6.4 6.3 8.1 0.3 0.0 1.7 0.0 6.9 0.3 0.0 0.0 0.0 0.8 0.8 0.3 0.1 2.8 1.3 0.0 0.0 0.3 11.1 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 8.8 0.0 0.0 0.5 0.2 0.0 0.0 5.1 0.0 0.7 0.3 70.4 0.0 0.0 0.0 0.0 65.4 12.8 0.4 0.3 35.8 0.0 0.0 34.7 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.4 10.6 0.0 0.0 0.0 TNFRSF1B "CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80" ENSG00000028137 "TNF receptor superfamily member 1B" P20333 1 12166991-12209228 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.4" "Cell type enhanced" "Detected in many" "dendritic cells: 268.7;Kupffer cells: 200.5;Langerhans cells: 288.0;Macrophages: 230.2;monocytes: 175.3;T-cells: 138.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 387.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 34.0;K-562: 45.7;THP-1: 51.8;U-87 MG: 30.8;U-937: 37.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004796 Approved "Secreted to blood" NA NA 3230000 8100000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA004796: AB_1078436" "unprognostic (4.45e-2)" "unprognostic (2.27e-3)" "unprognostic (7.62e-2)" "unprognostic (3.82e-3)" "unprognostic (6.30e-2)" "unprognostic (4.47e-3)" "unprognostic (5.28e-3)" "unprognostic (2.79e-1)" "unprognostic (1.69e-2)" "unprognostic (1.73e-2)" "unprognostic (7.26e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.26e-2)" "unprognostic (1.10e-1)" 45.6 5.4 3.9 68.4 3.8 52.1 34.7 4.8 17.9 14.3 5.6 12.8 16.8 11.6 0.4 5.5 14.6 15.6 10.9 3.7 9.0 7.5 15.7 32.0 32.1 18.3 7.2 6.3 5.9 2.3 4.5 35.8 10.6 6.4 10.8 0.8 6.5 2.6 10.7 7.8 23.9 16.8 9.0 53.3 16.4 2.2 8.9 12.7 7.6 6.3 21.3 28.9 8.8 14.1 0.0 0.3 4.1 0.0 9.6 13.5 8.9 1.1 2.0 4.0 4.3 1.8 34.0 0.2 0.6 3.9 5.6 0.0 0.8 0.0 2.2 14.5 0.0 0.0 0.2 0.0 25.2 0.3 3.8 14.8 0.0 13.0 0.0 7.2 19.6 0.2 45.7 6.4 1.5 0.0 0.0 8.1 0.2 4.9 1.4 1.2 0.4 25.9 0.0 0.8 0.0 0.1 0.6 0.4 1.4 6.4 0.0 51.8 7.8 5.3 0.2 27.0 0.0 1.9 0.0 0.0 30.8 37.0 1.4 0.6 127.1 18.2 48.4 260.5 26.5 13.5 34.4 40.5 71.7 8.4 9.8 15.5 138.0 13.4 387.1 15.1 70.9 150.4 3.9 3.8 4.8 17.9 3.7 9.0 18.3 7.2 10.6 9.0 8.9 14.1 99.4 9.6 15.9 0.7 42.8 16.8 3.9 1.0 1.2 0.2 3.2 4.1 3.6 5.7 6.5 3.7 0.0 0.9 268.7 12.8 0.0 0.5 0.6 1.7 5.1 46.0 0.0 7.4 0.2 0.6 6.3 13.2 12.8 4.9 2.5 1.4 31.1 17.0 72.6 0.0 0.2 3.0 0.0 200.5 288.0 1.2 2.1 230.2 16.0 30.9 175.3 0.3 109.2 0.0 0.1 0.7 4.2 0.4 72.5 8.0 25.8 0.4 1.5 1.2 32.9 6.8 9.8 0.0 0.9 0.7 10.5 30.1 138.4 1.9 4.8 8.8 TNN TNW ENSG00000120332 "Tenascin N" Q9UQP3 1 175067833-175148075 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 12.0;breast: 4.9" "Cell type enhanced" "Detected in some" "Adipocytes: 6.1;Fibroblasts: 7.5;Hepatic stellate cells: 2.5;Langerhans cells: 2.5;Smooth muscle cells: 10.4" "Cancer enhanced" "Detected in some" "breast cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.6;NB-4: 3.6;THP-1: 11.1;U-266/70: 2.7;U-937: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB010907, HPA026726, HPA026764" Uncertain "Secreted to extracellular matrix" NA NA 34000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "CAB010907: AB_477565, HPA026726: AB_10601771, HPA026764: AB_10601859" "unprognostic (1.16e-3)" "unprognostic (2.23e-2)" "unprognostic (1.35e-1)" "unprognostic (2.21e-2)" "unprognostic (1.34e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (3.55e-1)" "unprognostic (5.25e-3)" "unprognostic (1.01e-2)" "unprognostic (4.69e-1)" "unprognostic (5.07e-1)" "unprognostic (1.08e-3)" "unprognostic (1.76e-2)" "unprognostic (9.38e-3)" "unprognostic (1.89e-2)" "unprognostic (1.02e-2)" 12.0 0.2 0.0 0.1 0.1 0.0 4.9 0.0 0.1 0.1 0.1 0.3 0.8 0.0 0.0 0.1 0.0 1.7 0.3 0.2 0.0 0.4 1.3 0.4 0.1 0.0 0.1 0.0 0.3 0.8 2.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 3.1 0.4 0.4 0.1 0.4 0.4 0.1 0.1 0.1 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 11.1 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 6.1 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.7 0.0 0.1 7.5 0.0 0.1 0.0 0.0 2.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 10.4 0.4 1.4 0.0 1.8 0.1 0.1 0.0 0.0 0.1 TOR1AIP1 "FLJ13142, LAP1, LAP1B, LAP1C" ENSG00000143337 "Torsin 1A interacting protein 1" Q5JTV8 1 179882042-179920077 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 275.9;Late spermatids: 190.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047151, HPA050546, HPA070991" Enhanced Enhanced "Nuclear membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "Nuclear membrane" "HPA047151: AB_2679956, HPA050546: AB_2681167, HPA070991: " "unprognostic (1.41e-1)" "unprognostic (3.95e-3)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (9.00e-2)" "unprognostic (6.33e-2)" "unprognostic (7.04e-2)" "unprognostic (8.62e-2)" "unprognostic (1.93e-1)" "unprognostic (9.10e-2)" "unprognostic (4.40e-2)" "unprognostic (4.41e-2)" "unprognostic (2.87e-1)" "unprognostic (7.75e-2)" "unprognostic (4.02e-2)" 39.7 34.8 20.4 27.2 23.6 84.5 33.9 22.4 25.0 42.6 29.0 46.5 15.9 40.5 35.9 40.6 31.6 34.3 38.5 18.1 21.4 36.5 38.4 35.5 34.2 23.6 23.3 54.5 27.9 36.9 20.1 28.5 22.0 43.8 22.8 25.1 31.5 43.2 54.1 20.1 23.6 41.0 21.2 35.0 31.3 27.0 21.5 27.5 46.8 74.8 27.6 40.4 26.4 24.5 37.1 36.4 24.9 32.3 109.7 73.6 47.7 48.2 57.7 44.5 45.6 28.5 68.5 9.7 52.1 50.2 31.8 63.5 23.6 39.6 52.8 62.9 23.2 26.4 31.5 28.5 50.4 90.8 78.4 57.8 29.8 55.3 51.3 50.1 40.9 39.5 39.2 47.6 47.9 33.1 37.4 28.5 35.5 47.9 13.9 22.8 38.9 25.5 43.7 71.3 20.9 29.2 60.7 57.9 83.6 36.6 44.3 91.9 41.9 60.7 26.5 42.0 58.8 53.4 75.3 19.5 23.6 49.3 95.1 177.7 86.0 205.3 76.4 94.8 89.6 54.9 68.9 76.8 90.8 66.7 71.0 73.1 132.8 74.6 127.5 65.1 81.9 115.5 20.4 23.6 22.4 25.0 18.1 21.4 23.6 23.3 22.0 21.2 21.5 24.5 42.4 32.1 36.1 21.2 33.9 43.3 64.4 21.3 48.3 11.8 27.5 17.8 30.2 18.6 24.2 20.2 16.7 16.2 44.1 13.1 13.7 20.5 275.9 25.9 30.9 33.6 20.3 25.2 13.6 25.2 26.0 51.7 23.4 48.4 36.1 19.8 36.8 27.4 27.6 6.7 16.9 10.6 20.3 48.5 26.1 190.0 47.5 40.4 14.2 21.5 36.6 40.5 35.0 15.6 26.9 29.0 12.5 58.6 32.8 48.4 11.1 19.2 29.2 13.6 26.3 72.5 38.0 14.0 20.4 38.1 37.5 18.2 47.5 23.6 8.3 54.0 TXNDC8 "bA427L11.2, SPTRX-3, TRX6" ENSG00000204193 "Thioredoxin domain containing 8" Q6A555 9 110303476-110337884 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 101 "testis: 21.9" "Group enriched" "Detected in some" 182 "Early spermatids: 357.8;Late spermatids: 590.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "THP-1: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.50e-1)" "unprognostic (1.13e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 357.8 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 590.4 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UBAC2 "FLJ30548, PHGDHL1, RP11-178C10.1" ENSG00000134882 "UBA domain containing 2" Q8NBM4 13 99200774-99386504 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013448 Approved Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA013448: AB_1855301" "unprognostic (7.04e-2)" "unprognostic (1.19e-1)" "unprognostic (2.43e-1)" "unprognostic (7.30e-3)" "unprognostic (2.23e-1)" "unprognostic (2.79e-3)" "unprognostic (9.48e-3)" "unprognostic (6.50e-3)" "unprognostic (1.58e-1)" "unprognostic (6.95e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (6.44e-2)" "unprognostic (6.13e-3)" "unprognostic (3.33e-2)" "unprognostic (1.16e-1)" "unprognostic (6.08e-2)" "unprognostic (3.26e-2)" 15.3 13.3 9.0 18.2 9.3 19.6 20.0 7.3 9.2 21.3 9.9 21.5 30.7 19.9 17.9 28.6 27.6 22.6 27.3 10.1 8.4 21.9 27.7 16.9 25.4 10.9 9.6 19.1 17.4 30.0 2.7 29.4 8.8 18.4 22.9 7.6 25.8 17.3 39.0 30.6 23.3 19.7 11.6 20.8 17.7 26.2 12.6 29.3 30.0 38.9 27.3 23.9 8.6 8.8 51.8 26.8 22.4 33.9 52.2 62.8 56.3 25.9 73.3 40.3 36.4 29.2 108.7 19.9 43.8 34.8 27.0 49.2 28.8 41.1 22.0 33.8 33.7 37.2 16.9 22.5 48.7 48.2 28.1 45.9 54.9 24.6 71.0 54.6 38.8 39.6 31.1 13.3 31.6 14.3 32.1 15.3 32.6 104.0 27.0 27.6 24.9 15.2 32.7 29.6 25.2 40.3 21.0 67.8 41.4 39.4 41.5 148.7 30.3 21.9 19.0 20.1 29.5 16.3 12.0 6.6 42.9 71.9 38.3 64.6 53.7 41.9 61.3 57.3 87.3 48.1 53.8 62.6 46.2 55.2 73.6 74.5 48.8 84.6 57.5 57.3 40.2 88.1 9.0 9.3 7.3 9.2 10.1 8.4 10.9 9.6 8.8 11.6 12.6 8.8 28.7 6.4 19.1 58.8 45.3 27.1 26.0 41.7 40.5 27.3 31.2 24.3 23.8 21.5 29.4 23.9 27.1 111.6 48.5 37.3 23.5 44.1 26.0 24.5 21.7 26.4 8.4 31.3 110.9 34.9 84.6 31.6 19.4 21.9 22.2 34.3 17.9 29.1 48.5 32.0 103.0 30.1 40.7 39.1 121.4 22.0 35.1 88.4 30.2 81.5 35.7 48.8 69.0 82.0 73.3 29.0 32.6 50.8 11.7 48.7 48.0 22.6 31.6 21.2 32.9 24.7 32.1 66.2 35.1 31.7 33.1 132.4 66.0 54.4 39.1 34.4 UBE2Q1 "NICE-5, PRO3094, UBE2Q" ENSG00000160714 "Ubiquitin conjugating enzyme E2 Q1" Q7Z7E8 1 154548577-154559028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063368 Approved Approved Nucleoplasm,Centrosome,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Centrosome, Cytosol" "HPA063368: AB_2684996" "unprognostic (3.88e-1)" "unprognostic (2.13e-1)" "unprognostic (4.44e-3)" "unprognostic (3.64e-3)" "unprognostic (5.32e-3)" "unprognostic (6.10e-3)" "prognostic unfavorable (8.74e-4)" "unprognostic (2.92e-1)" "unprognostic (2.07e-1)" "unprognostic (9.92e-3)" "unprognostic (3.79e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.84e-7)" "unprognostic (2.20e-1)" "unprognostic (4.46e-1)" "prognostic favorable (1.86e-5)" "unprognostic (1.04e-2)" 25.4 23.1 36.1 19.0 37.0 32.2 22.4 34.5 43.3 21.2 35.2 24.3 18.7 21.8 27.2 27.4 23.7 19.9 25.9 37.3 38.0 28.8 31.6 25.0 29.5 36.0 36.0 23.1 31.8 28.3 31.3 23.9 37.5 21.2 28.2 25.9 22.5 20.9 26.3 26.7 25.5 24.4 35.5 32.3 26.8 34.6 38.2 29.8 23.0 25.8 35.2 25.7 22.2 36.2 39.0 33.0 45.6 35.0 45.8 46.9 39.4 38.0 57.0 47.3 38.0 37.3 40.4 47.5 53.3 52.8 39.5 33.0 54.3 43.6 40.5 48.7 34.3 37.8 29.6 36.4 57.5 62.1 58.3 45.5 56.7 38.5 44.1 51.3 61.8 43.3 32.4 57.1 61.3 60.4 38.1 45.6 62.5 92.3 55.5 43.4 31.8 50.3 52.4 40.6 46.2 64.6 38.1 70.6 64.5 77.5 43.3 93.2 43.3 30.5 34.1 36.5 41.2 69.3 55.2 62.1 34.2 43.2 47.1 3.9 1.3 2.9 2.1 1.6 2.0 1.4 2.0 2.7 1.2 1.5 2.2 2.5 2.0 2.3 1.3 2.4 3.1 0.8 36.1 37.0 34.5 43.3 37.3 38.0 36.0 36.0 37.5 35.5 38.2 36.2 40.8 32.1 26.5 9.8 24.7 16.2 18.0 15.9 15.4 41.2 27.3 32.5 29.4 27.1 18.4 16.5 4.2 19.8 45.2 33.4 11.7 14.5 4.5 24.8 20.9 32.8 33.6 12.0 12.2 21.0 18.2 23.3 14.3 24.9 10.8 31.9 35.3 38.3 27.5 60.6 11.7 29.2 22.4 48.0 19.7 7.3 17.7 27.9 14.2 10.3 30.9 42.8 39.1 7.1 11.7 26.2 18.5 19.2 22.1 29.5 29.6 19.7 29.0 23.1 13.1 20.1 21.2 34.1 29.2 18.1 19.0 19.6 26.5 36.3 25.7 31.4 UFC1 HSPC155 ENSG00000143222 "Ubiquitin-fold modifier conjugating enzyme 1" Q9Y3C8 1 161152776-161158856 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 703.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027481, HPA028722" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 62000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" Cytosol "HPA027481: AB_10599850, HPA028722: AB_10601674" "unprognostic (2.16e-1)" "unprognostic (6.17e-2)" "unprognostic (1.83e-1)" "unprognostic (8.25e-3)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (1.29e-3)" "unprognostic (2.15e-1)" "unprognostic (1.62e-2)" "unprognostic (3.40e-2)" "unprognostic (5.04e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (2.62e-6)" "unprognostic (3.49e-1)" "unprognostic (1.87e-1)" "unprognostic (2.13e-1)" "unprognostic (6.22e-2)" 85.3 112.1 135.3 76.1 139.3 134.5 134.0 137.6 167.5 100.4 138.9 114.5 112.6 91.7 170.6 100.2 209.3 103.2 111.9 135.4 149.2 129.5 115.4 87.8 107.6 136.4 139.0 140.7 164.7 148.0 102.4 92.9 143.0 106.5 141.9 85.1 126.0 112.2 101.0 110.5 103.1 108.4 139.6 79.1 116.3 56.3 137.6 110.4 108.9 108.3 128.6 125.9 76.8 142.3 140.7 119.8 107.8 129.9 137.5 226.7 223.5 124.7 154.0 122.7 111.8 165.0 268.6 183.2 232.8 180.7 77.3 65.7 89.1 127.2 96.1 154.4 238.6 109.4 163.0 200.9 139.8 233.4 271.9 190.4 202.6 152.5 104.6 207.4 227.9 189.4 183.0 123.8 159.8 161.3 126.1 234.9 198.9 387.9 128.5 152.6 80.8 258.6 248.4 158.2 112.9 196.2 108.1 324.2 163.8 176.8 148.2 482.1 165.6 90.5 92.2 90.7 196.1 233.3 322.2 177.5 140.7 164.8 119.7 137.3 156.7 104.5 174.7 164.1 212.8 209.3 185.0 188.2 192.4 164.1 161.9 175.4 28.4 208.3 121.6 206.4 274.4 268.1 135.3 139.3 137.6 167.5 135.4 149.2 136.4 139.0 143.0 139.6 137.6 142.3 107.0 70.5 85.3 18.3 151.9 99.8 173.3 244.6 106.4 57.4 174.2 177.5 117.6 147.3 171.6 104.8 41.7 253.8 170.8 150.8 440.3 224.2 131.0 421.2 96.6 123.3 204.5 124.7 8.7 380.8 386.9 99.2 111.6 113.2 119.7 143.1 116.7 106.2 244.7 47.1 7.7 240.0 205.4 150.7 138.5 392.3 105.0 132.0 131.6 9.4 229.3 161.8 195.7 11.1 13.3 265.5 189.1 91.0 182.6 148.0 243.5 380.9 703.0 72.0 65.7 86.3 106.7 96.6 42.4 125.2 120.9 431.9 155.1 124.4 193.7 218.6 UQCC2 "bA6B20.2, C6orf125, Cbp6, M19, MGC14833, MNF1" ENSG00000137288 "Ubiquinol-cytochrome c reductase complex assembly factor 2" Q9BRT2 6 33694293-33711727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 911.7;Late spermatids: 1207.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039111 Uncertain Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 38: Heart - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "Nuclear bodies" "HPA039111: AB_2676352" "unprognostic (3.58e-2)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (1.93e-1)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (3.21e-2)" "unprognostic (1.50e-1)" "unprognostic (2.35e-3)" "unprognostic (2.43e-2)" "unprognostic (5.93e-2)" "unprognostic (2.33e-2)" "unprognostic (7.43e-2)" "unprognostic (5.77e-2)" "unprognostic (3.88e-1)" "unprognostic (1.07e-1)" 38.9 69.6 100.5 37.3 102.8 45.3 45.3 103.3 140.9 48.4 97.6 43.3 34.3 61.5 58.4 59.2 40.0 20.8 267.2 100.1 106.6 66.9 83.3 33.9 35.6 102.5 102.2 33.4 61.2 46.8 78.0 29.3 102.9 55.4 44.0 104.3 53.0 28.6 228.8 42.9 28.5 52.4 102.4 43.2 49.5 104.1 104.4 45.7 42.9 197.9 40.8 46.1 42.8 107.9 207.7 144.2 162.8 139.4 130.9 129.8 125.5 116.4 117.3 167.7 162.6 233.9 84.5 84.4 180.3 143.5 244.1 109.0 111.7 164.5 138.6 108.0 187.7 163.3 87.3 327.6 215.9 153.8 127.2 136.2 257.4 131.7 204.7 91.0 120.4 158.9 178.4 165.9 190.4 220.9 149.0 315.9 97.3 158.4 167.6 106.5 130.7 279.9 116.2 191.5 273.1 97.1 127.9 191.7 165.6 84.1 168.3 382.2 110.5 178.0 151.1 115.9 242.0 126.8 193.1 146.6 53.7 229.7 211.0 32.7 88.5 18.2 76.1 141.6 93.6 152.4 95.0 87.6 108.6 116.1 98.7 88.0 8.4 81.6 120.9 133.2 110.7 123.8 100.5 102.8 103.3 140.9 100.1 106.6 102.5 102.2 102.9 102.4 104.4 107.9 18.5 28.9 29.3 8.1 54.2 58.5 96.8 193.0 61.5 108.7 96.0 100.3 911.7 74.4 119.8 77.3 50.1 134.7 34.0 112.4 391.3 103.4 342.3 46.6 78.7 54.1 99.7 105.0 8.9 179.7 124.4 88.5 90.7 39.1 59.5 90.0 41.4 166.1 218.8 70.7 10.2 94.5 154.6 67.8 55.6 1207.0 78.6 64.8 83.6 3.7 63.6 79.1 46.4 9.0 10.0 95.6 64.2 83.8 88.3 122.1 44.6 257.2 87.1 123.8 0.0 32.9 269.4 155.9 96.0 103.3 76.3 95.4 43.5 159.3 102.3 118.5 USF1 "bHLHb11, MLTFI, UEF" ENSG00000158773 "Upstream transcription factor 1" P22415 1 161039251-161045977 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001480, HPA036233, HPA036535" Supported Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "CAB001480: AB_2213986, HPA036233: AB_2675012, HPA036535: AB_2675178" "unprognostic (3.66e-2)" "unprognostic (2.79e-2)" "unprognostic (9.12e-3)" "unprognostic (2.17e-1)" "unprognostic (9.40e-2)" "prognostic favorable (8.70e-4)" "unprognostic (1.59e-3)" "unprognostic (2.94e-2)" "unprognostic (3.57e-1)" "unprognostic (1.03e-3)" "unprognostic (3.05e-1)" "unprognostic (2.44e-2)" "prognostic unfavorable (6.01e-12)" "unprognostic (1.24e-3)" "unprognostic (3.29e-1)" "unprognostic (4.08e-1)" "prognostic favorable (1.95e-5)" 15.3 18.2 26.3 18.9 26.2 17.5 13.9 26.2 27.2 14.8 25.7 18.4 18.5 14.3 14.2 13.8 16.8 14.6 18.4 26.5 26.6 15.7 21.0 18.4 27.8 26.0 25.5 16.7 11.4 20.5 11.4 18.1 26.4 15.1 18.3 17.0 14.0 18.2 32.7 15.3 19.6 18.1 26.0 30.5 14.9 7.6 28.2 36.0 12.9 29.4 32.7 20.7 13.7 26.9 17.2 25.5 29.9 35.0 39.4 22.3 39.9 14.0 30.3 42.9 33.3 17.9 21.2 22.1 29.0 23.5 18.6 21.0 35.6 22.3 24.0 20.6 21.2 19.1 20.9 18.9 23.0 26.7 25.4 18.3 22.0 31.1 25.1 27.3 40.7 36.8 31.7 23.1 27.2 20.1 41.5 29.2 61.8 37.0 32.9 35.6 23.3 26.9 21.0 26.8 16.9 32.3 25.5 32.8 18.1 42.9 27.5 85.5 24.0 21.5 13.5 13.2 23.1 19.5 26.6 34.3 18.3 25.9 16.7 2.5 2.6 1.4 1.9 2.1 1.1 1.5 1.1 1.3 2.6 1.7 1.2 1.2 4.1 0.9 2.1 2.7 1.3 1.3 26.3 26.2 26.2 27.2 26.5 26.6 26.0 25.5 26.4 26.0 28.2 26.9 13.1 6.4 6.9 3.6 18.0 2.3 0.6 3.1 9.1 3.3 2.7 3.9 1.0 0.0 3.2 3.7 2.1 2.2 14.5 7.1 1.9 2.1 0.4 5.5 8.1 6.0 3.0 5.0 6.3 1.3 4.4 4.6 14.8 5.6 11.4 4.0 1.1 0.4 3.1 5.0 5.4 3.4 6.1 2.1 3.5 0.2 0.3 12.4 5.4 4.7 4.7 1.6 4.1 4.0 5.8 2.3 7.1 0.0 20.0 1.6 7.3 3.1 7.9 3.5 6.6 3.3 4.9 0.5 0.4 8.5 1.8 3.4 9.3 7.7 4.9 1.9 UTS2 "PRO1068, U-II, UCN2, UII" ENSG00000049247 "Urotensin 2" O95399 1 7843083-7853512 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 43.0" "Cell type enhanced" "Detected in many" "dendritic cells: 15.3;granulocytes: 41.2;monocytes: 17.9;NK-cells: 88.6;T-cells: 18.2" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 5 "medulla oblongata: 43.0;pons: 27.0;white matter: 25.2" "Immune cell enriched" "Detected in many" 5 "T-reg: 45.2" "Lineage enriched" "Detected in many" 5 "T-cells: 45.2" "Cell line enhanced" "Detected in some" "CACO-2: 22.6;HEL: 7.1;HMC-1: 5.7;THP-1: 26.2" "Region enriched" "Detected in single" 19 "pons and medulla: 6.1" "Region enriched" "Detected in some" 12 "spinal cord: 79.7" HPA017000 Uncertain "Secreted to blood" NA NA 2590000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA017000: AB_1858656" "unprognostic (2.10e-3)" "unprognostic (1.35e-1)" "unprognostic (3.89e-3)" "unprognostic (1.33e-3)" "unprognostic (2.32e-5)" "unprognostic (1.09e-4)" "unprognostic (4.95e-2)" "unprognostic (6.69e-2)" "unprognostic (1.40e-1)" "unprognostic (2.65e-2)" "unprognostic (1.28e-1)" "unprognostic (1.89e-1)" "unprognostic (2.52e-5)" "unprognostic (1.75e-1)" "unprognostic (1.44e-1)" "unprognostic (2.47e-1)" "unprognostic (3.30e-3)" 0.5 3.7 0.1 0.5 0.1 2.9 0.1 1.5 0.5 0.3 0.0 0.7 0.6 0.1 0.0 0.1 0.4 0.5 0.0 0.2 4.6 0.3 0.1 0.5 1.8 43.0 6.2 0.3 0.0 0.0 0.0 0.0 27.0 1.4 1.2 0.9 0.0 0.0 0.3 0.3 0.5 1.2 4.0 1.1 0.2 0.0 0.9 0.9 0.1 0.0 0.3 0.2 0.1 25.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.1 0.0 0.2 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 8.5 0.1 0.6 5.0 0.0 6.7 0.0 4.4 4.5 0.8 0.0 0.4 1.3 0.1 6.1 0.0 0.0 45.2 1.7 0.1 0.1 1.5 0.5 0.2 4.6 43.0 6.2 27.0 4.0 0.9 25.2 0.1 0.0 1.9 0.0 5.1 1.5 0.1 0.1 1.8 3.2 0.0 0.0 0.1 0.0 0.7 1.8 0.0 0.0 15.3 2.7 0.0 0.0 0.0 0.0 0.1 0.3 1.2 1.7 0.4 0.0 0.0 0.6 1.1 0.1 41.2 0.0 0.0 0.0 0.1 5.0 0.5 3.7 0.0 0.0 1.3 0.0 0.0 5.5 0.0 1.0 17.9 0.8 88.6 0.5 0.2 0.1 4.7 0.0 4.3 1.2 3.0 0.6 0.0 1.2 0.0 0.2 0.3 0.0 0.0 0.8 0.4 0.1 18.2 0.0 8.0 0.0 VLDLR "CARMQ1, CHRMQ1, VLDLRCH" ENSG00000147852 "Very low density lipoprotein receptor" P98155 9 2621182-2660056 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 77.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 78.1;Cone photoreceptor cells: 104.3;Oligodendrocytes: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 6.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.3" "Cell line enhanced" "Detected in many" "BEWO: 22.3;JURKAT: 20.5;THP-1: 33.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032462, HPA051312" Uncertain Uncertain "Vesicles,Cytokinetic bridge,Centriolar satellite" Yes NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Cytokinetic bridge, Centriolar satellite" "CAB032462: AB_2216805, HPA051312: " "unprognostic (5.31e-2)" "unprognostic (2.65e-1)" "unprognostic (6.92e-2)" "prognostic favorable (5.95e-4)" "unprognostic (1.15e-1)" "unprognostic (2.67e-2)" "unprognostic (2.48e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-1)" "unprognostic (3.00e-2)" "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (6.75e-2)" "unprognostic (1.48e-2)" "unprognostic (1.93e-1)" "unprognostic (1.80e-2)" "unprognostic (4.34e-2)" 15.7 16.3 2.7 2.2 6.4 0.8 8.5 5.3 4.2 10.3 6.4 6.6 0.5 9.6 3.2 19.2 13.8 2.9 43.7 3.2 5.3 10.6 3.1 10.7 0.7 7.7 5.6 77.5 27.4 19.5 6.5 5.9 5.9 6.6 2.0 12.3 11.6 2.0 26.2 5.3 1.9 6.8 4.0 5.5 9.0 6.0 4.9 0.8 11.6 11.7 1.7 12.5 10.4 9.8 0.1 0.8 14.3 0.4 1.5 0.5 22.3 7.0 2.2 1.7 4.3 3.6 0.3 0.0 6.4 2.8 0.6 0.3 3.4 5.6 4.5 9.7 2.4 0.1 1.6 1.8 1.9 9.2 1.7 1.5 3.3 0.7 0.1 7.6 0.7 20.5 0.0 17.4 1.1 0.9 1.1 1.1 9.9 1.5 0.9 0.1 0.4 0.0 6.4 0.4 2.5 2.4 0.6 0.6 10.4 7.5 0.3 33.3 0.3 2.8 4.5 0.1 3.3 14.1 6.1 2.6 14.7 8.2 0.6 0.0 0.0 6.3 0.2 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 2.7 6.4 5.3 4.2 3.2 5.3 7.7 5.6 5.9 4.0 4.9 9.8 4.2 16.0 8.8 1.0 0.1 2.7 1.2 18.7 4.6 23.8 4.3 3.9 78.1 1.5 9.7 5.5 104.3 13.2 1.6 9.8 1.9 11.3 5.7 8.6 6.1 3.6 10.9 0.0 8.3 10.3 29.0 17.2 3.1 19.3 0.0 5.7 2.2 2.8 2.3 11.8 10.9 1.4 24.4 1.0 1.1 2.8 7.8 0.6 10.6 2.8 1.0 3.9 0.0 8.0 39.1 8.6 4.3 10.9 0.5 5.1 0.0 8.0 11.9 32.5 0.0 2.7 9.4 8.2 6.4 5.0 2.0 3.4 1.7 15.9 1.3 6.0 VPS36 "C13orf9, CGI-145, Eap45" ENSG00000136100 "Vacuolar protein sorting 36 homolog" Q86VN1 13 52412602-52450634 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039734, HPA043947" Approved Supported "Vesicles,Lysosomes,Plasma membrane,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 43: THP-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Vesicles, Lysosomes" "Plasma membrane, Cell Junctions" "HPA039734: AB_2676652, HPA043947: AB_2678744" "unprognostic (2.43e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-1)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-1)" "unprognostic (6.57e-2)" "unprognostic (7.84e-2)" "unprognostic (3.96e-3)" "unprognostic (1.19e-2)" "unprognostic (9.37e-2)" "unprognostic (5.57e-2)" "prognostic favorable (9.91e-6)" "unprognostic (6.47e-3)" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (9.83e-2)" 17.1 15.1 10.1 16.8 11.5 8.6 26.1 14.0 16.3 20.0 9.6 24.5 27.6 18.7 12.2 23.7 16.8 16.6 24.0 11.8 10.1 25.4 23.6 19.9 19.5 12.4 11.0 17.9 17.9 23.3 11.0 25.0 12.8 21.8 27.5 43.1 25.2 18.3 23.4 51.1 27.7 20.7 9.9 24.1 18.1 4.0 12.1 22.3 22.5 26.2 20.7 18.9 21.3 12.1 7.3 11.8 20.4 13.5 21.1 29.3 17.8 16.7 12.5 16.1 9.6 14.3 22.9 25.5 8.6 23.8 10.6 20.1 16.6 19.7 18.0 19.3 16.0 30.2 18.7 12.8 25.3 40.2 31.4 20.5 37.9 11.2 18.0 18.0 16.6 33.6 22.7 21.8 31.8 9.6 30.4 40.6 19.5 29.0 6.3 31.0 11.9 15.9 28.7 18.9 10.4 22.0 11.9 27.3 25.9 24.0 15.9 67.1 26.3 10.3 12.6 10.3 19.1 16.3 22.0 26.8 10.6 28.4 24.7 15.6 14.6 12.3 12.3 16.3 19.8 15.3 13.5 15.4 15.6 13.0 12.2 13.1 3.6 21.6 22.7 16.3 16.0 13.7 10.1 11.5 14.0 16.3 11.8 10.1 12.4 11.0 12.8 9.9 12.1 12.1 54.2 83.3 51.5 41.1 49.9 42.8 48.9 57.6 62.0 132.2 51.6 72.8 80.8 38.6 47.7 33.1 120.9 60.2 83.4 62.6 68.4 35.4 1.2 28.0 45.9 55.7 49.8 31.1 57.0 29.3 43.0 46.6 36.7 37.0 44.3 44.9 38.2 54.0 43.8 52.2 54.6 64.1 40.7 44.0 29.1 3.7 49.7 47.1 28.4 36.5 60.8 39.8 59.8 44.7 40.7 29.8 63.0 52.3 55.0 65.4 77.4 78.5 33.2 265.8 46.0 52.7 76.1 15.3 25.9 83.5 58.2 38.2 48.2 40.6 58.6 45.4 VPS72 "Swc2, TCFL1, YL-1, YL1" ENSG00000163159 "Vacuolar protein sorting 72 homolog" Q15906 1 151176304-151195321 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065709 Approved "Nuclear speckles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA065709: AB_2685540" "unprognostic (2.55e-1)" "unprognostic (3.79e-1)" "unprognostic (3.10e-1)" "unprognostic (4.50e-2)" "unprognostic (2.16e-2)" "unprognostic (7.00e-2)" "prognostic unfavorable (4.41e-6)" "unprognostic (4.10e-2)" "unprognostic (2.25e-1)" "unprognostic (1.10e-2)" "unprognostic (9.58e-2)" "unprognostic (1.50e-1)" "unprognostic (7.92e-2)" "unprognostic (4.52e-2)" "unprognostic (4.92e-2)" "unprognostic (4.49e-2)" "unprognostic (1.30e-1)" 23.8 21.0 33.3 17.0 34.1 12.9 22.7 35.3 39.7 27.5 30.0 26.8 16.8 28.1 19.0 25.0 23.5 15.0 25.4 32.9 35.9 24.9 17.9 18.7 21.2 34.2 33.6 25.8 21.5 21.2 19.1 22.3 34.6 25.8 16.2 18.2 23.5 18.1 56.3 24.3 20.5 24.2 33.6 23.5 23.8 18.7 34.3 27.9 20.0 32.3 26.3 32.2 23.6 36.5 60.7 41.0 92.8 66.9 40.1 35.0 79.5 64.2 33.8 50.4 36.4 43.7 49.4 60.6 77.3 48.7 35.0 56.0 69.1 41.4 38.0 72.2 75.4 52.3 31.0 30.2 55.7 77.8 46.0 28.5 56.8 57.4 47.5 52.8 66.7 74.3 100.2 44.5 40.3 103.3 67.0 54.8 108.5 107.5 69.2 73.2 52.9 95.3 47.1 30.5 65.5 116.8 44.1 67.6 78.9 86.6 76.5 114.4 63.2 26.5 44.9 42.7 82.3 82.5 124.9 96.4 43.4 52.9 49.9 63.3 48.8 82.4 57.2 47.5 55.4 65.8 50.9 49.3 55.3 53.9 50.3 45.6 35.7 75.3 40.6 35.2 67.5 58.3 33.3 34.1 35.3 39.7 32.9 35.9 34.2 33.6 34.6 33.6 34.3 36.5 23.3 6.4 9.1 7.5 21.9 28.4 28.6 40.0 28.5 13.7 24.8 32.1 15.1 24.3 26.8 23.9 4.2 57.6 19.1 24.6 64.6 49.9 12.2 15.2 18.1 25.2 20.3 30.9 6.3 46.4 53.5 24.3 20.9 17.4 31.7 25.4 25.0 18.1 32.0 15.2 6.9 30.6 63.1 22.9 18.8 9.7 25.1 17.7 42.7 2.8 33.8 32.8 29.9 4.5 9.1 59.8 30.5 24.8 13.5 31.4 28.6 35.4 15.7 12.9 52.6 23.3 40.7 39.5 30.4 23.5 31.7 63.1 24.8 16.1 27.1 35.5 WDR49 FLJ33620 ENSG00000174776 "WD repeat domain 49" Q8IV35 3 167478684-167653983 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 31.3;choroid plexus: 29.3;fallopian tube: 10.0" "Group enriched" "Detected in some" 5 "Astrocytes: 79.0;Endometrial ciliated cells: 43.4;Respiratory ciliated cells: 47.7" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 2.7;myeloid DC: 2.2;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 24 "dendritic cells: 2.9;monocytes: 2.7" "Cell line enhanced" "Detected in some" "AF22: 2.7;NTERA-2: 3.0;THP-1: 14.5;U-937: 7.8" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 9.5" "HPA036225, HPA036226" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nuclear bodies" Cytosol "HPA036225: AB_10696652, HPA036226: AB_2675007" "unprognostic (1.68e-3)" "unprognostic (1.24e-3)" "unprognostic (2.48e-2)" "unprognostic (1.96e-1)" "unprognostic (5.67e-2)" "unprognostic (5.11e-3)" "unprognostic (1.66e-1)" "unprognostic (6.02e-2)" "unprognostic (9.28e-3)" "unprognostic (1.34e-1)" "unprognostic (4.60e-9)" "unprognostic (1.79e-4)" "unprognostic (3.50e-2)" "unprognostic (3.57e-2)" "unprognostic (2.07e-1)" 0.1 0.1 10.2 0.4 8.2 2.0 0.1 16.6 3.4 0.3 29.3 0.1 2.0 0.4 0.0 0.9 10.0 0.2 2.1 7.0 15.6 0.3 0.0 1.9 0.3 30.1 27.0 0.1 0.3 0.0 0.5 0.0 23.8 0.2 0.1 0.0 0.2 0.0 0.0 0.1 4.6 0.1 31.3 0.4 0.2 0.6 15.5 0.4 0.0 0.2 0.3 0.2 0.2 23.4 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.8 0.0 0.0 2.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.5 10.2 8.2 16.6 3.4 7.0 15.6 30.1 27.0 23.8 31.3 15.5 23.4 0.2 0.0 0.6 79.0 0.1 0.0 0.9 1.7 9.1 0.0 0.1 0.1 1.1 0.0 10.9 0.0 0.0 0.0 1.6 0.1 0.0 0.1 2.4 43.4 0.3 0.2 0.0 1.7 4.5 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 4.1 1.6 2.5 0.8 0.0 1.8 0.0 0.0 4.0 0.0 0.0 2.5 3.0 0.0 0.0 0.0 0.1 0.4 3.3 0.0 47.7 0.0 6.6 0.3 0.6 0.1 0.2 1.0 0.1 0.0 0.1 0.0 0.2 0.8 WDR73 "FLJ14888, HSPC264" ENSG00000177082 "WD repeat domain 73" Q6P4I2 15 84639285-84654343 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 98.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039357 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 51: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" "HPA039357: AB_10673242" "unprognostic (8.49e-2)" "unprognostic (2.16e-1)" "unprognostic (4.77e-2)" "unprognostic (6.86e-2)" "unprognostic (1.74e-1)" "unprognostic (1.48e-1)" "unprognostic (1.18e-2)" "unprognostic (6.59e-2)" "unprognostic (1.02e-1)" "unprognostic (2.32e-2)" "unprognostic (1.26e-2)" "unprognostic (7.19e-4)" "unprognostic (9.21e-4)" "unprognostic (4.12e-1)" "unprognostic (3.16e-2)" "unprognostic (8.58e-2)" "unprognostic (4.02e-2)" 2.2 3.6 1.8 2.2 2.1 2.8 3.3 3.0 2.3 3.2 3.1 3.2 2.3 3.4 4.2 2.7 3.3 1.5 2.2 2.3 2.1 3.2 2.3 2.4 2.3 2.0 2.2 3.3 3.1 3.7 3.2 1.6 2.3 3.5 2.7 3.4 2.9 2.4 2.2 3.0 3.1 2.9 1.8 3.3 2.9 1.8 2.1 3.0 3.9 1.8 2.8 2.9 2.8 2.8 2.8 4.6 5.5 2.7 2.7 3.1 2.8 1.4 2.7 2.4 1.8 4.3 4.7 3.2 1.5 4.7 2.5 6.6 6.4 4.3 2.6 1.7 3.4 2.3 5.5 2.5 3.7 3.4 3.2 5.6 4.0 3.9 5.5 4.5 2.2 3.9 3.9 1.8 1.4 4.7 4.0 5.1 4.7 2.9 1.9 4.2 4.1 2.4 3.7 7.0 3.5 5.8 3.6 5.1 5.8 3.0 8.4 6.5 2.4 2.9 3.3 3.1 4.2 3.4 6.0 2.6 5.1 5.7 4.2 0.4 0.3 0.4 0.4 0.4 0.4 0.3 0.2 0.4 0.1 0.6 0.3 0.3 0.8 0.4 0.2 0.3 0.1 0.4 1.8 2.1 3.0 2.3 2.3 2.1 2.0 2.2 2.3 1.8 2.1 2.8 17.0 25.6 32.8 21.9 17.5 5.4 18.9 18.6 12.5 48.4 16.9 20.1 1.1 27.1 25.9 29.5 73.0 33.6 14.4 13.9 23.5 27.6 4.8 32.2 26.3 14.9 18.0 14.3 13.6 14.0 16.1 18.2 16.3 21.8 17.1 38.0 18.9 9.5 13.2 40.4 15.2 13.8 22.4 10.7 5.1 2.3 22.7 9.8 5.4 15.0 17.4 36.8 21.6 13.6 12.2 17.3 11.5 16.1 8.4 17.7 10.1 20.7 70.1 98.5 6.6 27.2 17.7 44.9 18.0 8.7 5.3 25.7 17.1 44.5 15.0 13.9 YBX1 "BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1" ENSG00000065978 "Y-box binding protein 1" P67809 1 42682418-42703805 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2038.9" "Cell type enhanced" "Detected in all" "Early spermatids: 8388.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005875, HPA040304, HPA057159" Supported Supported "Endoplasmic reticulum,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1600000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Endoplasmic reticulum, Vesicles, Plasma membrane" "CAB005875: AB_2219278, HPA040304: AB_10795364, HPA057159: AB_2683355" "unprognostic (8.59e-2)" "unprognostic (5.16e-2)" "unprognostic (9.27e-3)" "unprognostic (2.68e-3)" "unprognostic (7.76e-2)" "unprognostic (8.03e-3)" "prognostic unfavorable (9.87e-10)" "unprognostic (2.80e-2)" "unprognostic (2.31e-2)" "unprognostic (2.79e-3)" "unprognostic (7.51e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (3.59e-7)" "unprognostic (3.66e-2)" "unprognostic (2.44e-1)" "unprognostic (1.94e-2)" "unprognostic (3.25e-1)" 532.0 254.5 141.7 422.4 155.4 863.9 401.1 153.3 157.7 331.8 154.4 600.2 364.9 406.2 211.3 365.0 337.0 209.8 789.7 140.6 159.4 318.9 309.9 396.3 407.9 175.1 160.2 311.7 266.7 133.8 122.2 242.2 178.8 307.8 378.1 391.8 270.5 219.5 2038.9 295.0 366.1 338.9 152.7 367.1 405.0 783.5 180.8 353.4 282.0 1133.9 382.2 501.5 332.3 173.5 1552.8 761.5 1020.4 1232.7 991.0 908.1 1200.2 971.5 768.9 1116.6 875.8 1034.6 1253.7 1630.6 1157.5 825.2 495.5 870.2 1162.6 1230.5 1103.9 1087.8 1278.0 1596.4 1491.9 1343.8 786.7 2214.4 1320.7 812.6 1092.3 1094.5 1365.7 630.0 950.3 1271.9 1823.0 720.6 1104.0 837.7 2816.5 2464.6 2902.1 755.0 1006.4 1789.6 1972.5 1938.2 1176.7 933.8 1731.6 1298.5 893.7 1294.0 2038.3 1096.8 443.2 5002.2 862.6 945.4 1748.6 1371.1 2209.3 1213.7 1670.6 2004.8 910.4 1750.3 1049.9 15.3 48.4 69.9 42.9 107.1 52.9 69.4 51.8 43.3 77.4 61.2 44.0 45.9 9.0 35.1 124.2 58.6 69.7 34.1 141.7 155.4 153.3 157.7 140.6 159.4 175.1 160.2 178.8 152.7 180.8 173.5 701.7 173.1 230.9 16.3 818.3 1397.7 1265.9 419.7 747.3 247.8 569.7 564.5 1072.3 441.8 355.5 325.5 150.1 753.9 678.4 620.6 1457.6 1013.6 8388.7 363.5 695.5 755.1 587.8 2244.2 16.2 886.6 1998.9 687.6 461.3 427.0 383.1 489.1 483.3 480.1 1708.7 121.1 27.1 930.2 354.0 1656.0 2342.9 3743.4 751.2 1307.6 905.4 19.7 1171.0 463.8 744.6 23.6 32.7 858.2 975.1 806.1 981.0 1935.1 993.3 1169.8 196.2 602.4 466.8 754.8 1083.7 3245.2 425.5 1113.5 1302.5 481.5 635.6 811.4 1257.7 1697.8 YY1AP1 "HCCA2, YAP, YY1AP" ENSG00000163374 "YY1 associated protein 1" Q9H869 1 155659443-155689000 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA006986, HPA064249" Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Nucleoli fibrillar center" "HPA006986: AB_1080620, HPA064249: AB_2685226" "unprognostic (1.96e-2)" "unprognostic (2.80e-1)" "unprognostic (1.09e-2)" "unprognostic (5.67e-2)" "unprognostic (3.91e-2)" "unprognostic (1.77e-1)" "unprognostic (2.86e-3)" "unprognostic (1.23e-1)" "unprognostic (6.95e-2)" "unprognostic (8.13e-2)" "unprognostic (6.87e-2)" "unprognostic (8.65e-2)" "prognostic unfavorable (2.01e-6)" "unprognostic (6.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.39e-1)" "unprognostic (5.84e-2)" 41.9 36.1 35.4 28.1 38.6 77.2 42.8 51.1 41.6 47.1 20.7 56.6 23.5 41.5 38.6 53.0 44.2 26.7 48.1 33.5 32.7 42.3 38.3 49.3 38.6 32.6 35.2 47.5 37.6 35.4 47.1 32.0 32.4 46.3 35.6 41.3 41.0 37.6 113.8 54.0 39.7 42.6 31.7 47.9 41.8 74.6 38.8 50.4 39.9 73.2 49.8 45.8 45.8 41.3 63.5 32.0 40.3 45.9 44.9 40.4 86.5 39.9 58.0 70.4 59.9 49.3 65.7 50.1 38.4 58.6 35.8 60.5 61.3 55.7 66.2 46.7 30.5 41.6 36.2 31.2 47.5 66.7 54.2 43.0 56.1 53.7 68.5 48.8 44.3 47.5 55.8 69.9 52.2 56.0 68.5 32.4 63.7 86.5 46.4 53.7 34.9 80.4 42.7 45.5 40.3 47.8 52.6 75.0 51.5 72.5 82.3 108.7 36.0 39.4 34.6 41.4 53.5 87.7 62.8 123.2 38.9 43.0 46.4 40.3 27.6 50.3 34.7 27.5 36.8 26.7 29.6 36.4 34.0 20.9 25.5 25.5 29.5 45.0 27.7 15.9 40.1 35.1 35.4 38.6 51.1 41.6 33.5 32.7 32.6 35.2 32.4 31.7 38.8 41.3 18.3 19.2 26.7 28.7 26.0 34.7 30.5 20.2 38.7 24.5 27.4 21.3 23.2 22.8 22.9 12.9 43.8 23.6 24.5 25.7 13.7 17.3 68.0 20.0 21.8 24.5 34.9 42.9 33.8 19.1 27.9 24.7 25.0 25.5 25.3 16.6 15.7 23.1 21.5 16.8 34.8 23.8 12.2 20.8 36.3 81.0 28.0 28.5 19.6 37.5 27.4 20.8 15.5 38.7 48.3 18.4 16.2 25.6 36.9 29.2 22.5 11.7 17.3 24.9 6.6 24.9 22.3 77.6 25.5 38.8 35.7 45.0 26.7 26.6 24.4 33.8 ZDHHC11B ENSG00000206077 "Zinc finger DHHC-type containing 11B" P0C7U3 5 710355-784729 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "brain: 29.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 23.0;Excitatory neurons: 47.2;Inhibitory neurons: 38.3;Oligodendrocyte precursor cells: 26.7;Oligodendrocytes: 70.1;Respiratory ciliated cells: 21.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.1;SCLC-21H: 2.4;THP-1: 3.4" "HPA057886, HPA069008" Uncertain Approved Mitochondria NA NA "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA057886: AB_2683548, HPA069008: AB_2686068" "unprognostic (2.81e-1)" "unprognostic (8.38e-3)" "unprognostic (3.79e-2)" "unprognostic (5.11e-3)" "unprognostic (7.18e-2)" "unprognostic (4.02e-3)" "unprognostic (1.19e-1)" "prognostic favorable (3.98e-4)" "unprognostic (4.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.45e-4)" "unprognostic (6.94e-2)" "unprognostic (1.43e-2)" "unprognostic (9.21e-2)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (2.31e-1)" 0.7 1.2 15.1 0.2 19.6 0.0 0.8 5.9 19.9 0.5 0.0 2.0 2.7 0.4 0.1 1.5 2.0 0.3 4.5 14.6 9.0 0.7 1.2 2.4 0.0 14.2 8.6 0.6 1.8 0.4 4.5 0.2 14.9 0.5 2.3 4.3 1.7 0.5 3.6 2.2 2.4 0.4 3.3 1.2 2.3 0.7 15.5 0.0 1.1 1.6 0.3 1.0 0.6 29.5 0.0 0.8 0.0 0.7 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 2.1 0.1 0.0 0.3 0.4 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 2.4 0.4 0.0 0.0 0.7 0.3 0.0 3.4 0.0 0.0 0.6 0.0 0.0 0.8 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 19.6 5.9 19.9 14.6 9.0 14.2 8.6 14.9 3.3 15.5 29.5 0.2 19.2 23.0 17.0 0.0 2.7 1.0 0.1 2.2 7.0 1.1 0.9 8.9 1.5 5.7 3.7 0.0 0.0 0.4 2.0 0.0 0.8 2.5 11.9 0.7 2.8 3.0 0.0 47.2 0.8 0.1 4.7 4.1 3.6 1.3 0.0 0.7 2.3 1.7 10.1 38.3 6.7 0.0 0.6 1.1 0.4 0.9 0.8 0.0 1.9 0.0 0.6 0.0 26.7 70.1 0.1 1.4 0.0 1.7 0.3 7.7 0.5 21.8 0.3 6.6 1.4 2.4 5.0 2.5 2.3 3.1 0.0 1.5 0.5 2.4 2.6 ZEB2 "KIAA0569, SIP-1, SIP1, ZFHX1B" ENSG00000169554 "Zinc finger E-box binding homeobox 2" O60315 2 144364364-144521057 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Epilepsy, Hirschsprung disease, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 363.7" "Cell type enhanced" "Detected in many" "Horizontal cells: 662.9;Inhibitory neurons: 539.3;Oligodendrocytes: 1489.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 154.0;THP-1: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003456 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoli "Nucleoplasm, Cytosol" "HPA003456: AB_10603840" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (4.12e-1)" "unprognostic (4.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.77e-2)" "unprognostic (5.83e-2)" "unprognostic (7.90e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (6.04e-5)" "unprognostic (1.11e-2)" "unprognostic (1.73e-2)" "unprognostic (7.45e-2)" "unprognostic (1.32e-2)" 61.3 45.2 185.6 56.8 258.3 127.5 29.5 138.3 165.5 52.4 3.0 24.5 21.9 29.6 9.6 27.9 20.3 43.9 45.7 132.5 155.4 18.2 23.3 41.2 43.2 238.3 214.5 70.5 5.7 6.7 3.3 62.1 222.8 18.5 29.9 35.5 9.6 22.7 20.8 12.8 25.9 33.3 183.2 69.4 18.0 16.2 249.6 10.6 13.3 18.8 24.2 46.6 24.1 363.7 1.6 2.0 83.4 0.1 98.9 49.7 0.3 35.1 35.1 38.5 37.1 0.0 0.8 6.6 0.1 37.4 10.6 0.4 14.5 0.1 47.6 37.6 11.2 154.0 6.3 0.2 23.0 26.4 113.2 42.1 0.9 48.9 22.9 33.7 29.4 0.0 43.0 4.1 45.2 0.2 0.4 79.9 12.3 0.0 1.9 44.1 63.5 0.2 0.4 0.6 0.7 22.1 4.2 0.2 97.3 27.5 0.2 181.4 45.9 42.9 0.7 87.5 11.0 47.1 0.3 7.5 66.7 78.4 122.6 27.8 47.7 12.2 21.0 42.6 1.9 9.2 2.7 10.7 27.0 9.4 1.9 7.7 15.2 7.3 43.9 21.5 0.6 19.0 185.6 258.3 138.3 165.5 132.5 155.4 238.3 214.5 222.8 183.2 249.6 363.7 32.6 6.4 19.2 121.8 92.4 24.9 1.2 0.6 3.4 158.6 2.2 4.3 71.0 1.5 10.1 5.5 4.2 1.7 426.2 0.1 1.9 0.7 2.2 2.1 84.7 29.2 0.0 127.0 228.2 0.8 2.0 123.0 13.3 2.5 157.5 99.3 79.2 4.6 144.5 662.9 539.3 0.0 0.0 435.0 276.3 7.2 120.5 435.0 103.2 343.8 233.6 69.3 223.5 381.0 1489.6 0.2 1.1 66.5 132.3 1.8 0.0 10.3 4.0 11.9 184.1 185.0 198.7 2.9 11.3 3.4 19.6 4.7 136.7 108.8 0.4 2.2 ZFP69 "FLJ16030, ZFP69A, ZKSCAN23A, ZNF642, ZSCAN54A" ENSG00000187815 "ZFP69 zinc finger protein" Q49AA0 1 40477290-40496343 "Predicted intracellular proteins, Transcription factors" "Lipid metabolism, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 5 "THP-1: 58.2" "Not detected" "Not detected" "HPA027808, HPA054942" Uncertain Approved Nucleoplasm NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA027808: AB_10601031, HPA054942: AB_2682644" "unprognostic (1.07e-2)" "unprognostic (6.00e-2)" "unprognostic (7.58e-3)" "unprognostic (4.15e-2)" "unprognostic (1.52e-1)" "prognostic favorable (9.31e-4)" "unprognostic (7.21e-3)" "unprognostic (1.72e-1)" "unprognostic (8.40e-3)" "unprognostic (6.34e-3)" "unprognostic (2.31e-1)" "unprognostic (4.46e-2)" "prognostic unfavorable (5.00e-6)" "unprognostic (1.05e-1)" "unprognostic (3.14e-2)" "unprognostic (5.98e-2)" "unprognostic (2.81e-1)" 2.0 1.3 2.8 2.3 3.1 1.9 2.0 2.6 2.8 2.4 2.0 2.7 1.9 2.4 2.2 2.0 2.3 1.7 1.8 2.5 2.6 2.2 2.0 2.3 2.9 2.9 2.8 2.6 2.4 2.5 1.3 2.2 2.8 2.5 1.9 2.0 1.7 2.3 0.5 2.8 2.4 2.6 2.6 3.1 2.1 3.6 2.8 3.0 2.1 0.8 2.9 2.7 2.1 3.2 5.4 0.0 3.1 4.1 3.8 3.9 5.3 2.9 3.4 4.4 5.0 2.8 4.2 9.6 3.7 4.6 5.7 4.3 6.0 2.5 5.0 8.7 4.1 7.2 5.3 4.8 3.0 0.1 7.4 4.0 6.2 2.9 4.5 1.4 2.6 0.2 4.2 0.1 2.5 2.8 7.5 9.1 5.9 0.5 0.1 4.1 11.0 4.5 2.4 4.0 4.1 6.5 4.9 4.5 8.3 4.8 0.1 58.2 1.1 2.0 4.0 5.6 0.3 0.2 7.6 5.9 3.7 1.5 5.6 0.0 0.1 0.0 0.5 0.1 0.6 0.3 0.4 0.6 0.2 0.2 0.2 0.6 0.0 1.9 0.1 0.0 0.2 0.2 2.8 3.1 2.6 2.8 2.5 2.6 2.9 2.8 2.8 2.6 2.8 3.2 1.5 6.4 0.0 2.3 2.4 1.0 0.4 0.2 4.0 1.4 0.6 0.6 1.5 0.0 0.1 0.0 0.0 1.2 1.8 0.7 1.9 1.5 15.1 0.8 1.4 2.2 0.0 2.1 2.7 1.3 1.8 1.5 1.1 0.6 0.0 2.6 0.7 1.1 1.3 0.0 2.7 0.9 2.0 1.0 1.9 3.5 1.2 1.4 1.8 2.8 2.4 1.5 2.1 6.6 5.4 1.1 0.3 1.9 3.6 0.4 0.3 0.5 0.8 0.9 0.0 1.4 1.4 4.1 4.6 1.5 0.4 0.3 1.9 1.5 1.3 0.3 ZMPSTE24 "FACE-1, HGPS, PRO1, STE24, Ste24p" ENSG00000084073 "Zinc metallopeptidase STE24" O75844 1 40258041-40294180 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006988 Approved NA NA 50000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 1: Thyroid gland - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "HPA006988: AB_1080659" "unprognostic (6.32e-2)" "unprognostic (1.63e-2)" "unprognostic (3.75e-3)" "unprognostic (4.63e-2)" "unprognostic (4.16e-3)" "unprognostic (1.37e-1)" "prognostic unfavorable (5.73e-6)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (1.84e-3)" "unprognostic (4.78e-2)" "unprognostic (7.96e-2)" "unprognostic (5.06e-2)" "unprognostic (3.65e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (6.34e-4)" "unprognostic (2.71e-2)" 20.5 24.6 16.3 19.9 16.7 5.6 25.5 18.1 22.9 26.2 21.9 28.5 22.2 26.7 27.4 21.7 18.8 25.7 20.6 16.1 18.8 46.0 38.4 21.7 16.8 17.4 17.7 14.3 17.4 53.3 10.2 22.1 18.5 26.3 33.1 10.9 19.6 23.8 16.3 16.3 23.4 32.2 18.7 13.7 21.3 11.0 17.7 15.5 27.5 18.1 23.0 29.4 16.2 18.9 69.3 38.4 35.6 26.1 90.3 71.3 67.0 64.0 60.6 81.7 73.9 35.4 118.8 62.7 41.1 92.1 29.9 71.0 78.4 67.9 97.9 54.4 39.8 59.9 36.0 44.5 45.4 99.3 68.8 45.5 67.4 64.7 28.4 45.4 58.3 27.3 63.0 60.6 80.1 30.2 60.7 28.3 70.0 47.2 42.2 52.2 60.2 77.6 75.2 58.0 38.0 44.6 60.9 155.6 85.9 56.3 55.2 249.1 46.4 68.6 52.5 56.0 78.0 37.1 106.2 49.6 75.6 64.6 79.1 18.9 21.4 14.0 17.6 27.2 22.5 15.0 19.4 19.4 29.4 11.4 16.7 22.9 8.5 29.6 24.3 18.4 24.6 22.7 16.3 16.7 18.1 22.9 16.1 18.8 17.4 17.7 18.5 18.7 17.7 18.9 28.9 38.5 24.1 19.2 20.1 32.0 24.2 41.4 33.0 6.6 35.9 19.0 25.5 54.3 43.0 73.5 0.0 41.4 22.1 44.3 31.3 58.9 3.5 30.7 32.6 31.2 27.6 18.1 16.6 36.9 38.3 36.0 21.9 40.0 21.0 16.6 27.5 64.4 34.0 10.1 13.9 31.0 54.9 33.9 24.5 2.2 28.6 28.6 24.9 11.2 30.5 29.3 19.6 17.6 20.2 44.0 29.3 32.7 31.1 37.7 31.7 42.6 64.2 7.7 0.0 26.8 41.2 7.8 6.4 31.5 27.1 39.0 23.1 28.9 35.6 24.5 ZNF230 FDZF2 ENSG00000159882 "Zinc finger protein 230" Q9UIE0 19 44002957-44013924 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA006172 Approved Mitochondria No No "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA006172: AB_2667532" "unprognostic (3.55e-3)" "unprognostic (5.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.78e-1)" "unprognostic (2.01e-2)" "unprognostic (4.27e-2)" "unprognostic (5.88e-2)" "unprognostic (3.89e-2)" "unprognostic (3.79e-2)" "unprognostic (1.35e-1)" "unprognostic (4.08e-4)" "unprognostic (2.45e-2)" "unprognostic (1.14e-2)" "unprognostic (8.59e-2)" "unprognostic (1.68e-1)" "unprognostic (4.62e-2)" "unprognostic (1.42e-5)" 2.0 2.1 1.1 2.2 1.3 3.2 3.2 2.8 2.0 2.3 1.5 2.0 1.3 2.3 2.1 1.4 2.5 1.6 1.8 1.1 1.4 1.7 2.1 2.4 3.4 1.2 1.3 4.2 1.4 2.7 2.7 2.4 1.4 2.2 2.0 4.6 1.9 2.5 0.8 2.9 2.4 1.8 1.3 3.9 1.9 1.8 1.3 4.0 3.0 1.9 3.9 2.0 1.7 1.8 2.1 1.7 3.4 3.5 2.7 3.3 1.3 2.9 2.9 2.6 4.7 1.0 1.1 1.7 1.9 2.1 1.6 1.7 2.9 2.6 3.9 2.1 3.6 2.9 4.1 1.2 1.5 3.8 2.4 2.5 2.4 2.9 3.0 3.5 1.8 2.0 0.5 0.0 2.7 1.1 4.3 2.7 2.0 1.4 1.6 3.1 4.7 0.8 1.5 2.4 1.9 4.3 4.1 1.4 2.1 2.3 1.2 8.7 2.3 4.1 3.0 1.2 2.2 2.1 2.2 0.3 2.0 2.8 2.6 6.2 3.3 8.7 3.6 4.0 3.8 4.2 4.1 3.7 3.6 4.2 4.5 4.2 11.5 2.9 2.0 2.2 3.7 2.9 1.1 1.3 2.8 2.0 1.1 1.4 1.2 1.3 1.4 1.3 1.3 1.8 4.7 0.0 2.2 1.6 8.3 2.8 2.6 3.0 4.6 8.5 3.3 3.9 6.0 10.0 3.5 3.7 16.7 4.0 9.9 2.7 3.9 3.0 2.7 2.9 3.3 4.2 1.2 2.1 4.6 2.4 3.2 4.4 2.6 1.7 1.3 4.8 3.9 2.7 3.2 8.4 3.8 2.4 10.2 4.4 3.3 1.7 6.5 3.6 3.6 3.7 7.9 5.4 7.2 2.5 4.0 1.2 0.8 4.5 1.4 2.0 4.1 1.6 2.9 9.6 6.6 3.9 4.3 13.7 7.9 2.8 2.7 3.1 6.7 3.7 3.2 2.0 ZNF592 "CAMOS, KIAA0211, SCAR5" ENSG00000166716 "Zinc finger protein 592" Q92610 15 84748592-84806445 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020332, HPA021600" Approved Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA020332: AB_1859365, HPA021600: AB_1859364" "unprognostic (2.83e-1)" "unprognostic (1.90e-1)" "unprognostic (2.48e-2)" "unprognostic (2.35e-2)" "unprognostic (1.15e-1)" "unprognostic (7.63e-2)" "unprognostic (4.15e-1)" "unprognostic (2.26e-1)" "unprognostic (1.13e-1)" "unprognostic (5.04e-1)" "unprognostic (7.98e-2)" "unprognostic (2.84e-1)" "unprognostic (4.80e-3)" "unprognostic (3.64e-1)" "unprognostic (6.62e-2)" "unprognostic (3.90e-1)" "unprognostic (2.62e-1)" 9.7 8.7 9.4 6.7 10.0 11.1 9.6 10.4 9.4 9.7 7.4 9.4 7.9 9.1 7.9 7.4 9.8 4.9 9.6 9.8 9.0 8.7 10.9 9.0 9.5 11.5 10.1 11.8 10.9 9.1 7.9 5.9 10.2 8.7 7.1 7.5 7.5 6.5 18.2 10.1 10.7 6.8 9.3 11.2 8.1 8.0 10.2 11.4 8.8 14.5 9.4 8.5 8.3 10.6 7.7 12.8 11.6 6.5 12.7 8.5 12.8 5.3 7.5 8.6 6.8 12.2 8.9 11.1 6.7 11.9 7.4 13.9 18.0 7.6 6.0 9.0 10.8 12.9 12.9 11.0 7.8 10.6 9.9 9.4 10.6 6.7 11.0 10.2 7.6 7.7 13.0 6.8 9.1 12.0 7.2 13.0 10.6 7.3 5.0 10.3 10.4 9.8 9.2 15.4 10.5 11.4 12.1 10.7 9.0 16.1 6.0 22.3 10.8 12.7 7.4 7.1 10.2 7.8 9.0 11.8 8.0 15.5 7.5 0.0 1.2 0.9 1.2 1.4 0.4 1.5 0.7 1.2 1.3 1.4 1.0 0.9 2.6 1.0 1.3 1.0 0.8 0.8 9.4 10.0 10.4 9.4 9.8 9.0 11.5 10.1 10.2 9.3 10.2 10.6 9.2 9.6 10.5 23.8 15.2 8.4 4.2 8.2 6.2 9.0 14.3 8.8 5.3 8.6 7.5 3.7 8.4 5.6 9.6 18.8 0.0 8.4 7.8 24.7 10.8 9.8 7.8 12.0 21.7 8.1 8.9 8.7 13.7 40.3 3.8 10.2 10.4 16.7 11.3 3.3 20.7 10.8 4.1 21.1 9.8 11.8 4.7 14.6 7.2 28.1 14.9 3.7 11.3 10.1 29.9 9.8 11.1 9.8 16.9 5.6 16.2 6.3 8.4 8.5 6.6 13.1 9.2 13.2 12.4 8.9 7.1 4.8 11.6 8.1 11.4 5.1 ZNF684 MGC27466 ENSG00000117010 "Zinc finger protein 684" Q5T5D7 1 40531573-40548167 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 36.0" "Low region specificity" "Detected in all" HPA059153 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Cytosol Nucleoplasm "HPA059153: AB_2683932" "unprognostic (4.56e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-4)" "unprognostic (2.29e-2)" "unprognostic (2.96e-2)" "unprognostic (3.67e-4)" "unprognostic (8.49e-2)" "unprognostic (2.26e-3)" "unprognostic (2.10e-2)" "unprognostic (7.00e-2)" "unprognostic (4.14e-3)" "unprognostic (3.96e-2)" "prognostic favorable (4.89e-10)" "unprognostic (4.76e-3)" "unprognostic (7.11e-2)" "unprognostic (5.98e-2)" "unprognostic (1.52e-2)" 2.4 3.7 1.7 2.2 2.6 6.4 3.0 2.0 3.3 1.7 2.2 2.8 2.3 2.4 2.8 1.7 1.7 2.4 7.7 1.5 1.8 6.9 12.4 2.5 3.3 2.3 2.2 2.6 2.6 3.3 1.2 1.5 2.6 1.8 3.4 2.1 2.5 1.4 3.3 2.9 1.9 2.3 1.4 3.1 3.2 3.2 2.3 3.4 3.8 2.8 2.7 1.7 1.4 3.9 2.9 0.9 3.6 4.8 3.2 4.8 2.1 2.6 2.5 3.2 5.4 1.7 3.7 5.0 2.1 1.7 2.1 3.5 3.6 2.7 4.9 4.4 6.3 5.4 3.2 4.9 1.7 5.7 5.7 3.0 1.0 3.8 1.5 1.8 4.6 4.0 2.9 6.9 4.5 0.9 8.6 6.6 8.8 1.3 2.8 4.1 10.3 3.6 4.7 2.5 2.5 4.4 4.7 4.5 5.2 4.7 2.0 36.0 2.8 2.9 6.3 3.1 5.1 5.8 4.8 5.9 2.6 5.9 4.8 4.1 1.9 1.0 3.0 4.1 1.6 3.5 2.0 1.7 1.2 1.5 1.3 2.6 1.0 1.9 2.2 1.9 2.6 1.3 1.7 2.6 2.0 3.3 1.5 1.8 2.3 2.2 2.6 1.4 2.3 3.9 4.9 6.4 3.2 10.4 6.8 2.3 1.6 2.2 4.6 3.4 2.0 2.8 13.0 5.7 2.9 7.3 0.0 1.2 7.2 3.2 17.6 5.7 6.5 1.6 3.2 5.0 1.2 4.2 7.8 14.7 2.5 4.2 1.5 1.8 2.5 4.6 4.2 15.8 4.8 3.3 7.9 2.2 4.1 4.2 2.3 3.7 2.5 4.2 8.8 5.6 6.3 4.3 4.1 12.5 16.1 6.4 2.0 3.0 3.2 1.0 1.1 17.3 4.3 2.6 0.0 5.8 4.8 8.7 4.6 1.7 1.3 0.0 5.9 5.3 3.2 1.5