Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AAAS ENSG00000094914 "Aladin WD repeat nucleoporin" Q9NRG9 12 53307456-53324864 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040086 Approved Approved "Nuclear membrane,Centrosome,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear membrane" "Centrosome, Cytosol" "HPA040086: AB_10805602" "unprognostic (1.53e-1)" "unprognostic (1.24e-1)" "unprognostic (1.83e-1)" "unprognostic (1.81e-2)" "unprognostic (1.76e-1)" "unprognostic (2.64e-1)" "unprognostic (1.51e-3)" "unprognostic (1.70e-1)" "unprognostic (4.34e-1)" "unprognostic (1.00e-2)" "unprognostic (1.57e-2)" "unprognostic (6.64e-2)" "prognostic unfavorable (2.93e-4)" "unprognostic (1.95e-1)" "unprognostic (9.82e-2)" "unprognostic (2.53e-1)" "unprognostic (7.44e-2)" 17.0 36.3 12.3 13.8 15.0 19.1 17.1 15.2 15.6 20.3 15.1 19.1 12.3 19.1 7.2 19.3 19.9 9.4 22.7 12.9 13.7 21.7 24.6 14.0 17.6 14.3 14.1 19.2 23.9 18.0 24.8 17.4 14.8 18.4 15.1 12.3 18.5 11.7 22.6 17.3 17.7 16.8 13.7 22.2 21.6 27.3 14.0 25.2 19.4 18.5 21.6 17.8 17.9 17.2 26.1 77.3 63.2 38.0 28.6 32.2 38.9 29.8 31.3 72.6 42.1 54.0 56.7 62.2 47.4 37.3 41.9 37.6 106.4 78.8 42.1 41.0 68.1 49.7 29.9 40.7 26.4 45.5 37.9 28.1 39.4 48.9 44.6 40.4 56.6 56.2 67.6 70.6 30.4 72.8 71.2 46.1 40.0 27.7 53.1 72.1 39.3 69.4 38.2 17.5 32.8 41.3 20.2 46.9 21.0 40.2 61.2 38.8 25.5 34.9 51.1 27.4 32.9 32.5 43.5 54.7 25.6 39.6 40.5 1.0 17.7 10.7 18.4 20.2 20.8 20.0 15.9 16.8 18.8 21.8 21.7 21.4 1.1 10.5 22.5 22.6 17.4 15.2 12.3 15.0 15.2 15.6 12.9 13.7 14.3 14.1 14.8 13.7 14.0 17.2 11.7 12.8 7.8 17.9 15.1 7.4 19.0 26.2 10.2 11.8 13.2 13.0 8.2 17.2 15.4 14.7 16.7 58.4 13.7 9.3 13.7 20.4 12.5 11.9 12.9 11.7 8.4 41.2 7.3 18.3 49.5 14.9 13.3 8.9 8.2 13.1 11.0 12.0 28.5 1.7 6.6 13.1 18.3 12.4 9.3 26.2 17.7 10.6 10.6 5.6 11.6 18.0 15.5 6.6 11.4 8.9 11.0 12.8 20.8 8.1 11.2 18.5 12.6 15.5 19.7 11.0 39.7 34.2 40.5 13.1 7.4 36.5 11.4 14.9 17.2 13.0 AAMP ENSG00000127837 "Angio associated migratory cell protein" Q13685 2 218264129-218270178 "Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017717, HPA031868" Approved Supported Microtubules,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Microtubules Cytosol "CAB017717: , HPA031868: AB_2674078" "unprognostic (1.57e-1)" "unprognostic (6.12e-2)" "unprognostic (8.11e-3)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.39e-2)" "unprognostic (5.04e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (8.94e-2)" "unprognostic (7.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (4.22e-2)" "unprognostic (5.51e-2)" "unprognostic (1.23e-3)" "unprognostic (5.26e-2)" "unprognostic (1.92e-1)" "unprognostic (9.09e-2)" 66.5 66.4 65.0 46.2 66.1 27.5 65.2 67.1 80.1 62.6 63.2 76.3 62.8 61.7 43.8 75.1 60.8 56.1 65.4 65.7 67.2 60.2 77.5 46.6 47.8 69.2 66.6 79.8 70.7 72.7 62.1 54.9 66.4 58.0 58.0 38.4 66.9 58.7 90.4 76.6 61.7 50.7 67.5 53.0 86.9 53.8 67.1 54.0 66.6 62.0 52.6 70.0 57.4 70.3 126.1 104.6 75.1 102.2 111.9 75.7 146.0 89.6 136.3 167.1 124.5 226.2 100.1 64.6 121.8 112.6 158.8 94.3 150.7 133.4 129.3 103.5 200.9 147.4 108.2 237.4 158.9 139.3 92.4 97.8 152.7 172.2 149.7 99.7 97.6 124.3 202.6 82.4 108.9 198.0 112.4 234.9 121.0 182.4 75.4 90.6 97.5 105.8 100.3 160.5 96.2 92.9 59.4 128.7 134.7 119.1 99.1 104.6 84.7 110.2 82.3 81.2 106.8 105.7 198.1 108.4 111.0 88.6 77.4 75.9 166.2 60.3 101.1 209.2 105.1 100.3 90.1 94.9 191.4 105.7 111.1 100.7 26.2 114.9 210.6 114.1 109.3 179.4 65.0 66.1 67.1 80.1 65.7 67.2 69.2 66.6 66.4 67.5 67.1 70.3 57.8 41.7 35.2 11.4 50.4 90.5 86.1 122.9 66.0 47.7 50.7 45.2 35.5 41.5 74.0 42.3 12.5 160.0 42.2 74.3 103.7 95.7 3.5 33.5 46.4 50.6 75.5 34.0 11.5 95.4 130.3 63.4 80.5 38.2 34.8 57.6 42.5 46.2 91.9 63.9 12.9 89.9 93.6 37.0 65.3 8.8 83.3 38.5 62.2 5.6 64.8 80.2 41.2 8.0 10.5 86.6 72.0 74.9 51.2 116.0 99.5 85.3 47.4 37.1 65.7 38.4 86.5 72.0 53.3 70.2 97.3 202.6 44.4 62.5 103.5 119.9 ACADL "ACAD4, LCAD" ENSG00000115361 "Acyl-CoA dehydrogenase long chain" P28330 2 210187126-210225447 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 28.0;pancreas: 28.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.9;Early spermatids: 85.6;Late spermatids: 69.4;Leydig cells: 46.9;Peritubular cells: 46.6;Proximal tubular cells: 31.5" "Group enriched" "Detected in many" 8 "liver cancer: 2.2;prostate cancer: 6.8;renal cancer: 8.8;thyroid cancer: 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.4;RPTEC TERT1: 2.6;SuSa: 2.3;U-2 OS: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011990 Enhanced Supported NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" "HPA011990: AB_1844465" "unprognostic (6.29e-3)" "unprognostic (7.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (1.33e-2)" "unprognostic (7.66e-3)" "unprognostic (3.24e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (1.99e-1)" "prognostic favorable (1.58e-11)" "unprognostic (4.22e-3)" "unprognostic (1.18e-4)" "unprognostic (8.81e-3)" "unprognostic (1.06e-1)" 11.9 1.1 0.8 0.1 0.8 0.0 8.0 0.7 1.1 3.4 0.9 0.5 0.0 0.7 1.1 0.5 4.0 0.6 3.1 0.7 1.2 19.8 28.0 10.1 0.0 0.8 0.8 12.7 28.4 4.5 2.9 1.0 0.8 20.6 0.1 0.0 6.8 4.8 9.5 2.8 0.4 0.1 0.8 0.0 5.6 3.1 0.7 1.5 23.7 5.0 0.0 1.0 3.8 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.6 0.5 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.1 0.7 1.2 0.8 0.8 0.8 0.8 0.7 0.9 0.2 28.9 70.9 1.0 0.0 0.6 1.4 1.1 1.2 0.2 1.3 0.5 1.1 8.6 7.6 22.0 2.1 8.8 0.0 0.0 15.6 4.0 85.6 7.1 0.4 0.2 0.0 0.0 0.2 11.9 0.3 4.9 3.6 5.9 2.5 0.8 0.7 23.0 0.5 0.0 13.3 0.0 0.0 0.3 0.4 69.4 46.9 0.4 0.0 4.7 0.0 0.2 0.0 7.5 0.3 3.9 0.0 46.6 0.0 8.2 0.0 31.5 2.4 0.2 0.0 7.6 13.7 0.7 0.7 0.7 1.0 6.3 0.4 0.1 0.0 0.7 ACOT9 "ACATE2, CGI-16, MT-ACT48" ENSG00000123130 "Acyl-CoA thioesterase 9" Q9Y305 X 23701055-23766475 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035533 Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 7600 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA035533: AB_10696506" "unprognostic (5.69e-2)" "unprognostic (6.34e-2)" "unprognostic (1.59e-1)" "unprognostic (2.09e-1)" "unprognostic (1.53e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (1.12e-1)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (9.75e-3)" "unprognostic (3.49e-2)" "unprognostic (2.15e-3)" "unprognostic (6.53e-2)" "unprognostic (1.68e-1)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" 24.1 18.8 8.0 19.5 7.5 15.8 19.8 7.5 9.5 17.7 10.3 22.0 15.5 22.5 8.4 12.1 17.3 13.6 49.3 7.2 9.1 15.5 14.5 26.1 12.7 8.0 7.5 15.1 14.0 11.7 8.8 17.8 8.6 16.1 16.4 9.6 18.6 22.1 27.6 12.5 15.8 32.3 6.9 18.4 17.7 6.2 8.5 6.3 17.4 14.2 12.5 21.3 14.7 7.5 81.5 54.0 23.1 51.4 37.2 42.0 11.7 62.7 54.3 60.7 58.4 48.5 71.4 4.1 39.1 70.5 81.8 48.3 29.6 79.9 84.2 18.8 44.6 27.4 55.0 35.6 49.9 10.8 33.3 37.5 53.6 71.5 80.5 39.6 90.3 0.6 17.7 26.7 66.7 28.4 15.2 26.1 33.9 31.8 65.3 15.7 87.6 34.4 72.8 29.8 4.5 22.1 68.4 28.3 41.6 85.5 31.9 14.0 84.7 50.7 33.8 73.3 34.7 6.4 16.1 0.5 37.4 10.5 43.6 24.7 30.2 22.2 10.2 43.5 14.1 11.1 12.6 11.3 32.4 9.9 4.0 9.4 15.8 12.3 56.2 5.4 20.8 18.6 8.0 7.5 7.5 9.5 7.2 9.1 8.0 7.5 8.6 6.9 8.5 7.5 34.6 48.1 27.3 12.1 23.0 20.1 45.9 51.8 7.4 5.3 5.6 6.7 44.3 18.6 36.8 16.5 25.0 4.0 21.5 9.7 5.9 59.6 0.8 20.8 22.9 38.7 2.4 11.2 6.1 52.5 11.4 33.4 16.8 21.6 37.3 14.8 32.9 11.8 42.4 5.0 8.6 10.3 16.2 37.1 95.4 0.4 18.0 57.3 33.8 13.1 192.3 11.9 19.6 4.5 3.1 83.4 15.0 25.6 27.7 52.4 14.6 30.3 38.0 9.9 26.3 35.2 65.1 1.6 10.4 3.5 10.7 3.0 21.2 30.4 11.2 38.2 ACTBL2 DKFZp686D0972 ENSG00000169067 "Actin beta like 2" Q562R1 5 57480018-57482811 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.1;Club cells: 1.0;Ductal cells: 1.7;Early spermatids: 2.4;Exocrine glandular cells: 1.1;Pancreatic endocrine cells: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 1.3;RPTEC TERT1: 1.6;SiHa: 2.9;U-2 OS: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041264, HPA041271" Uncertain NA NA 830000000 "Cluster 38: EFO-21 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.83e-2)" "unprognostic (1.70e-1)" "unprognostic (2.96e-1)" "unprognostic (8.66e-2)" "unprognostic (2.57e-2)" "unprognostic (2.39e-1)" "unprognostic (3.63e-2)" "unprognostic (1.22e-1)" "unprognostic (1.14e-3)" "unprognostic (3.20e-1)" "unprognostic (2.48e-3)" "unprognostic (1.60e-2)" "unprognostic (2.04e-2)" "unprognostic (1.92e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.9 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.3 1.1 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 2.4 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 ACTR3 ARP3 ENSG00000115091 "Actin related protein 3" P61158 2 113890063-113962596 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005085, HPA047016, HPA051683" Approved NA NA 25000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "CAB005085: AB_2289106, HPA047016: AB_2679903, HPA051683: AB_2681573" "unprognostic (7.28e-2)" "prognostic unfavorable (6.52e-5)" "unprognostic (2.03e-2)" "unprognostic (1.01e-3)" "unprognostic (1.14e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (7.76e-5)" "unprognostic (9.27e-3)" "unprognostic (1.63e-1)" "unprognostic (2.50e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.81e-5)" "unprognostic (2.57e-1)" "unprognostic (2.54e-2)" "unprognostic (3.44e-2)" "unprognostic (4.44e-1)" 97.5 125.3 29.9 229.7 36.4 216.5 64.5 37.6 41.0 62.7 52.4 129.3 107.4 78.1 47.2 167.1 58.1 84.4 71.7 48.0 41.9 79.4 89.9 97.9 291.2 46.4 38.2 46.4 64.3 54.7 23.1 101.4 41.7 71.3 125.1 31.7 64.3 83.6 47.8 77.7 119.0 137.0 36.2 155.8 113.1 84.8 39.0 185.8 67.3 49.8 331.3 153.6 67.1 46.7 377.8 179.1 249.4 170.6 178.0 251.7 259.9 518.7 395.0 369.7 349.1 379.9 233.6 538.7 590.6 487.9 497.1 200.0 262.3 286.5 486.7 806.2 135.6 502.7 210.2 296.2 314.8 474.0 879.1 227.1 220.8 484.9 316.5 216.1 348.6 207.1 273.9 393.8 493.1 153.2 429.7 204.5 187.2 254.8 297.5 328.8 246.8 273.4 381.0 348.9 124.0 124.1 263.0 269.7 330.6 188.7 112.7 387.7 514.6 440.9 288.3 205.6 451.5 208.5 446.5 635.4 385.5 304.2 417.7 753.0 478.9 1048.4 464.4 728.1 381.6 455.9 424.6 460.6 634.4 385.0 371.4 437.9 777.1 479.9 887.7 191.4 587.0 1265.4 29.9 36.4 37.6 41.0 48.0 41.9 46.4 38.2 41.7 36.2 39.0 46.7 113.7 89.8 64.1 26.4 254.0 331.9 369.7 139.1 93.9 32.0 57.5 48.9 68.5 57.2 125.4 68.0 8.4 144.6 196.5 164.4 129.1 220.8 113.6 109.2 100.8 138.9 85.3 154.8 40.1 154.8 316.6 101.4 122.9 171.0 267.5 88.4 81.0 72.9 339.2 38.7 40.4 120.2 105.8 201.4 413.7 108.3 45.4 288.1 112.1 69.3 316.5 46.7 286.3 58.3 67.6 177.0 168.1 73.0 158.7 181.7 103.3 132.4 117.7 19.5 65.7 58.5 194.1 207.1 74.7 173.4 353.8 205.6 264.4 242.2 120.3 314.1 ACTR8 "ARP8, INO80N" ENSG00000113812 "Actin related protein 8" Q9H981 3 53867066-53882152 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 44.3;Late spermatids: 85.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 56.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065236 Supported Nucleoplasm,Centrosome NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Centrosome "HPA065236: AB_2685442" "unprognostic (9.05e-2)" "unprognostic (2.06e-1)" "prognostic favorable (2.21e-4)" "unprognostic (2.97e-1)" "unprognostic (5.67e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (5.11e-6)" "unprognostic (2.24e-2)" "unprognostic (4.68e-2)" "unprognostic (1.02e-1)" "unprognostic (2.82e-1)" "unprognostic (5.68e-2)" "prognostic favorable (7.88e-9)" "unprognostic (3.68e-1)" "unprognostic (3.35e-1)" "unprognostic (2.84e-1)" "unprognostic (1.15e-1)" 8.4 6.8 7.8 9.8 8.6 9.4 9.3 10.5 9.0 9.2 13.0 9.3 7.4 9.8 9.0 9.2 9.0 8.1 18.5 8.3 9.3 13.0 8.7 9.2 13.9 8.6 9.6 10.3 9.4 14.7 7.2 11.0 8.5 9.0 12.0 7.6 8.8 8.6 9.0 9.2 7.2 11.0 8.8 9.4 9.6 21.5 9.3 13.4 12.1 12.6 14.8 11.5 7.3 9.6 11.9 14.4 27.5 22.9 22.2 27.6 20.6 27.4 34.8 36.3 28.7 22.6 14.1 36.1 7.9 37.9 26.7 9.9 21.0 18.8 34.1 14.7 8.7 35.2 21.9 24.3 26.1 38.6 30.8 21.8 19.1 37.6 23.4 28.0 28.4 18.9 16.4 12.2 37.0 13.8 12.9 23.0 25.7 17.0 22.7 16.8 17.3 21.8 27.5 32.7 8.1 23.5 17.8 15.4 16.1 25.9 9.9 21.1 19.7 27.5 17.8 25.6 25.2 33.9 46.4 36.3 20.4 27.7 17.6 56.2 8.2 10.5 9.2 12.0 9.2 9.8 8.5 8.8 10.7 6.1 8.9 9.6 4.3 15.1 7.4 7.8 15.0 8.0 7.8 8.6 10.5 9.0 8.3 9.3 8.6 9.6 8.5 8.8 9.3 9.6 6.3 3.2 7.7 6.5 9.4 7.8 6.0 12.3 5.7 6.8 5.4 5.1 19.5 10.0 8.6 3.7 4.2 12.7 11.6 5.7 21.5 15.1 44.3 5.9 12.0 8.8 10.8 7.8 7.1 15.6 11.3 7.8 12.2 7.6 5.7 10.9 8.2 5.4 11.5 1.7 8.5 10.6 12.2 7.6 6.9 85.9 10.8 10.0 5.4 4.7 11.9 7.6 13.4 8.0 6.2 15.5 3.5 9.8 13.6 6.3 5.9 24.1 5.0 5.3 0.0 5.5 20.8 27.6 20.3 7.3 6.5 10.3 11.5 13.5 6.3 6.5 AIMP1 "EMAP-2, EMAPII, p43, SCYE1" ENSG00000164022 "Aminoacyl tRNA synthetase complex interacting multifunctional protein 1" Q12904 4 106315544-106349456 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Inflammatory response, Protein biosynthesis" "Cytokine, RNA-binding, tRNA-binding" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017618, HPA018476" Supported Enhanced Cytosol "Secreted to blood" NA NA 6500000 35000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB017618: AB_2285445, HPA018476: AB_1848137" "unprognostic (1.17e-3)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (2.36e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.29e-3)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (8.90e-2)" "unprognostic (5.86e-2)" "unprognostic (1.23e-2)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "unprognostic (7.13e-2)" "unprognostic (1.73e-1)" "unprognostic (2.27e-2)" 32.5 33.4 23.3 31.4 25.9 60.1 44.4 25.8 32.9 32.2 25.2 42.1 39.9 34.5 35.1 37.7 32.1 32.1 34.4 23.2 25.0 40.3 35.8 29.0 38.6 25.8 25.7 42.3 32.4 37.8 25.6 30.1 25.7 33.1 41.6 36.0 35.0 35.1 65.3 29.4 37.8 32.3 24.3 33.5 34.8 23.5 24.8 35.4 38.9 50.4 39.2 40.9 30.7 27.8 66.7 46.1 47.3 60.3 51.0 78.0 68.1 80.8 69.7 73.9 87.7 81.9 97.8 109.4 61.6 79.6 50.5 61.4 69.6 86.6 98.8 62.1 47.4 64.2 63.8 134.0 101.3 147.4 75.4 62.9 100.2 74.5 117.5 56.3 64.3 68.2 120.8 58.0 82.4 58.5 99.2 78.2 51.4 94.6 46.5 81.1 86.3 101.5 94.7 60.5 72.9 56.9 52.7 158.1 86.4 61.7 75.2 107.8 50.5 87.9 73.1 66.1 105.9 71.5 98.9 110.0 74.6 112.7 97.0 60.6 54.7 55.0 42.9 61.8 51.7 57.4 54.0 43.9 58.5 55.8 55.8 51.0 7.7 51.9 73.4 74.7 72.2 34.9 23.3 25.9 25.8 32.9 23.2 25.0 25.8 25.7 25.7 24.3 24.8 27.8 87.4 70.5 55.2 18.6 72.7 50.2 147.0 166.1 50.7 49.7 71.3 87.8 95.4 82.9 130.2 66.2 35.5 124.5 58.1 83.3 156.5 121.1 79.0 75.4 83.8 60.8 73.8 66.7 17.3 126.6 144.8 66.0 48.9 130.8 79.3 64.2 61.4 109.8 109.6 25.2 20.4 144.4 116.0 90.1 53.3 19.4 99.1 68.8 32.0 16.9 117.2 56.0 74.2 24.6 38.3 118.3 93.7 85.4 40.9 141.8 146.8 166.1 105.6 45.5 59.2 77.5 128.4 127.2 74.3 66.4 50.2 150.9 68.9 74.3 142.2 173.1 AMER1 "FAM123B, FLJ39827, RP11-403E24.2, WTX" ENSG00000184675 "APC membrane recruitment protein 1" Q5JTC6 X 64185117-64205708 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 15.3" "Cell type enhanced" "Detected in many" "Sertoli cells: 6.6;Theca cells: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065214, HPA065265" Approved Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" "Vesicles, Plasma membrane" "HPA065214: AB_2685435, HPA065265: AB_2685450" "unprognostic (1.56e-2)" "unprognostic (8.85e-2)" "unprognostic (6.86e-2)" "unprognostic (2.74e-1)" "unprognostic (2.12e-2)" "unprognostic (1.86e-1)" "unprognostic (3.57e-2)" "unprognostic (1.48e-1)" "unprognostic (8.02e-2)" "unprognostic (1.75e-1)" "unprognostic (6.31e-2)" "unprognostic (3.43e-1)" "unprognostic (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (6.19e-2)" "unprognostic (2.89e-1)" 1.1 1.4 1.6 1.3 1.5 1.2 1.3 1.8 1.6 1.9 0.1 1.5 1.5 1.9 4.0 2.8 2.2 1.0 1.3 1.0 1.6 1.8 2.1 1.2 1.2 1.5 1.4 6.3 2.0 1.6 0.7 0.8 1.5 1.7 1.3 1.3 2.2 2.2 4.1 2.2 1.3 2.8 0.7 1.3 1.6 0.4 1.9 1.6 1.4 15.3 1.6 1.3 1.3 1.0 3.1 2.2 5.8 4.6 2.2 2.1 4.7 1.4 1.2 2.1 1.3 7.3 1.1 5.9 1.8 3.0 1.6 4.3 12.5 4.1 2.0 2.5 2.5 3.7 4.9 4.9 1.6 7.7 0.9 3.0 5.3 1.6 3.2 1.7 1.2 4.6 5.6 5.9 1.1 3.7 5.2 4.0 15.6 4.0 4.4 11.7 9.4 4.3 0.9 1.0 2.6 3.9 3.7 5.0 1.9 4.8 1.6 2.1 0.8 2.5 5.8 6.7 1.9 3.0 2.2 4.4 1.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 1.5 1.8 1.6 1.0 1.6 1.5 1.4 1.5 0.7 1.9 1.0 0.9 0.0 0.0 1.0 1.5 2.2 0.6 0.9 2.8 5.0 1.7 1.5 2.6 4.3 0.3 0.0 2.1 1.1 3.4 1.1 0.0 1.2 0.1 3.3 2.6 1.5 1.2 0.8 0.8 1.6 0.8 1.8 3.6 2.0 0.0 3.9 1.4 2.6 0.4 0.0 1.3 1.0 0.0 1.0 0.3 0.2 2.5 0.5 1.8 1.0 1.2 0.2 0.0 1.0 0.6 0.7 0.5 4.1 2.4 1.2 0.8 0.8 0.0 1.0 6.6 2.3 4.4 0.0 0.2 3.6 2.6 0.7 0.9 6.4 1.6 0.7 ANAPC2 "APC2, KIAA1406" ENSG00000176248 "Anaphase promoting complex subunit 2" Q9UJX6 9 137174784-137188560 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 58.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018692, HPA066539" Enhanced Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB018692: AB_2258285, HPA066539: AB_2685688" "unprognostic (5.20e-2)" "unprognostic (8.86e-3)" "unprognostic (1.43e-2)" "prognostic favorable (8.91e-5)" "unprognostic (2.29e-1)" "unprognostic (2.38e-2)" "unprognostic (4.46e-1)" "unprognostic (4.84e-2)" "unprognostic (1.07e-1)" "unprognostic (3.36e-1)" "prognostic favorable (1.07e-7)" "unprognostic (7.41e-2)" "prognostic favorable (3.67e-4)" "prognostic favorable (2.87e-4)" "unprognostic (1.35e-1)" "unprognostic (8.46e-2)" "unprognostic (9.88e-2)" 14.4 17.7 8.8 11.3 9.6 15.0 15.8 8.9 13.4 15.2 8.6 14.4 11.9 15.8 3.1 15.8 14.7 8.6 15.6 9.7 8.1 14.2 20.2 13.1 14.5 11.5 9.1 15.2 20.7 7.4 13.8 7.2 10.2 17.5 3.1 4.3 18.2 8.9 18.9 19.2 16.5 5.3 8.1 19.9 17.0 25.5 8.8 10.2 15.5 8.3 6.1 13.8 13.4 12.9 20.9 45.6 10.7 17.5 12.6 7.5 33.5 18.5 11.5 16.9 12.8 27.8 20.9 22.4 21.3 12.3 15.8 41.9 12.9 13.8 2.5 28.9 22.5 13.3 55.1 24.9 14.9 20.7 22.1 15.0 10.9 11.3 6.1 8.3 20.8 20.7 20.3 26.4 8.0 58.2 24.7 28.7 21.6 27.4 34.6 29.3 26.5 41.4 13.1 18.1 14.1 21.3 28.2 36.5 11.9 5.1 39.2 27.8 22.4 24.8 19.8 30.1 16.7 12.9 20.5 24.5 20.1 14.1 18.3 0.3 0.6 0.1 0.5 0.6 0.3 0.3 0.3 0.4 0.5 0.2 0.3 0.4 0.2 0.3 0.9 0.6 0.3 1.1 8.8 9.6 8.9 13.4 9.7 8.1 11.5 9.1 10.2 8.1 8.8 12.9 9.3 0.0 0.5 6.2 12.2 9.3 7.9 14.2 6.2 5.7 13.0 12.6 3.2 11.5 11.5 11.0 4.2 25.9 11.1 19.0 13.7 10.0 40.5 4.2 4.0 9.0 10.2 9.5 2.4 10.9 11.1 9.0 27.0 5.0 11.4 8.5 12.1 11.1 15.6 1.7 2.5 19.1 12.2 8.8 7.8 58.4 11.1 7.6 14.2 1.0 13.9 3.7 6.2 1.5 4.3 8.6 8.0 9.4 15.3 6.8 21.2 15.8 10.2 4.7 0.0 9.8 17.4 40.5 26.4 11.9 9.5 24.5 9.4 5.9 15.4 7.1 ANGPTL6 "AGF, ARP5" ENSG00000130812 "Angiopoietin like 6" Q8NI99 19 10092338-10102796 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 30.2" "Cell type enhanced" "Detected in some" "B-cells: 4.1;Hepatic stellate cells: 5.7;Hepatocytes: 8.2;Smooth muscle cells: 15.8;Spermatogonia: 6.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HMC-1: 58.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 450000 23000000 "Cluster 24: B-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.28e-1)" "unprognostic (2.18e-6)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (2.16e-1)" "unprognostic (1.02e-2)" "unprognostic (8.77e-2)" "unprognostic (5.25e-2)" "unprognostic (1.00e-1)" "unprognostic (2.99e-2)" "unprognostic (1.23e-2)" "unprognostic (1.85e-1)" "unprognostic (2.26e-10)" "unprognostic (8.96e-2)" "unprognostic (4.41e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" 0.3 0.3 0.8 2.1 0.7 2.8 0.3 0.8 1.1 0.2 0.4 0.6 0.7 0.1 0.2 0.3 0.7 0.4 0.2 0.7 0.8 0.5 30.2 0.5 3.3 1.7 1.1 0.3 1.1 0.1 0.4 2.2 1.3 0.2 0.4 0.1 0.2 0.0 0.0 0.3 3.5 0.2 1.2 3.4 1.6 1.6 1.0 0.8 0.3 0.0 3.3 0.5 0.2 1.7 0.3 0.0 0.0 0.1 0.1 0.0 0.4 0.2 0.1 0.0 0.2 0.0 0.1 7.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 2.0 0.2 0.2 0.0 0.5 58.9 0.0 0.2 0.1 0.1 0.3 0.0 0.6 0.4 0.3 0.0 0.0 1.3 4.7 0.2 0.4 1.1 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.3 0.0 0.5 0.0 0.0 5.0 0.0 0.1 0.1 0.0 0.0 5.1 1.4 2.9 0.2 0.7 0.7 0.0 0.3 0.0 0.6 0.4 0.4 0.7 0.4 0.4 0.1 0.9 0.2 0.4 0.0 0.4 0.2 0.1 0.5 0.2 0.8 0.7 0.8 1.1 0.7 0.8 1.7 1.1 1.3 1.2 1.0 1.7 0.3 0.0 0.0 0.0 4.1 0.3 0.1 0.4 0.0 0.1 0.4 0.3 0.4 2.8 0.3 0.0 0.0 0.2 1.7 0.1 1.9 0.3 0.3 0.0 0.3 0.2 0.0 0.4 0.9 0.0 0.2 2.5 0.5 0.1 0.0 0.1 5.7 8.2 2.3 0.0 0.6 0.0 0.0 0.0 0.3 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 2.1 0.0 0.2 0.5 0.2 0.2 0.0 0.1 15.8 0.5 6.3 0.0 0.0 0.3 1.0 0.9 0.1 0.1 ANKFY1 "ANKHZN, BTBD23, KIAA1255, RANK-5, ZFYVE14" ENSG00000185722 "Ankyrin repeat and FYVE domain containing 1" Q9P2R3 17 4163821-4263995 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024513, HPA024522, HPA065849" Approved Enhanced Endosomes NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Endosomes "HPA024513: AB_1844830, HPA024522: AB_10601453, HPA065849: AB_2685567" "unprognostic (4.57e-3)" "unprognostic (1.25e-1)" "unprognostic (1.26e-1)" "unprognostic (9.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.42e-3)" "unprognostic (1.13e-1)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (4.14e-2)" "unprognostic (7.83e-2)" "unprognostic (2.55e-2)" "unprognostic (4.76e-3)" "unprognostic (2.11e-1)" "unprognostic (2.50e-1)" "unprognostic (1.80e-1)" "unprognostic (2.05e-1)" 13.8 16.1 18.9 13.5 25.4 16.4 12.5 23.4 19.0 15.2 15.1 25.8 11.4 18.0 10.6 13.6 15.1 11.9 11.4 17.8 23.9 11.3 13.9 15.3 14.0 27.5 23.6 19.9 9.6 19.0 12.3 14.2 25.4 12.1 13.9 13.1 13.7 12.2 14.1 19.8 13.7 14.8 25.8 15.0 13.0 5.9 22.9 20.3 14.4 11.4 12.8 14.6 13.9 28.1 20.6 47.2 31.5 21.3 41.7 31.6 20.5 22.5 23.4 35.5 35.2 21.0 13.7 17.8 18.0 34.1 19.0 32.0 29.3 24.0 31.2 9.7 29.7 17.6 34.0 19.6 23.2 10.6 20.4 33.3 24.8 25.5 18.7 19.0 21.3 17.2 17.3 16.7 24.5 16.0 15.9 11.3 13.3 16.0 16.4 23.9 21.0 9.9 18.5 27.7 10.5 16.4 31.9 15.1 20.2 24.3 17.5 13.7 27.3 22.5 11.7 31.0 30.3 5.5 4.6 5.9 27.5 21.1 27.5 1.0 3.9 1.7 2.7 6.4 2.5 0.9 1.8 1.9 2.7 0.9 1.8 1.7 1.6 1.0 7.3 1.1 1.7 2.2 18.9 25.4 23.4 19.0 17.8 23.9 27.5 23.6 25.4 25.8 22.9 28.1 14.5 28.9 24.6 43.1 8.7 12.4 8.9 12.7 13.1 24.1 12.2 13.2 4.6 8.6 13.6 18.4 29.2 11.2 15.1 13.8 1.9 9.8 4.3 13.9 20.0 15.1 12.1 6.3 59.9 9.7 9.8 15.2 18.8 12.5 3.8 21.1 24.7 19.7 20.2 26.9 60.5 10.9 6.1 24.4 7.6 3.8 14.6 19.1 17.8 39.4 18.8 9.8 19.6 36.7 46.4 13.2 6.4 19.2 7.4 15.4 11.4 7.6 22.4 30.2 6.6 25.5 11.9 12.9 12.8 17.2 11.6 6.2 15.5 16.6 12.5 14.5 ANP32D PP32R2 ENSG00000139223 "Acidic nuclear phosphoprotein 32 family member D" O95626 12 48472559-48473622 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Smooth muscle cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063133, HPA067561" Uncertain Enhanced Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Centrosome" Cytosol "HPA063133: AB_2684947, HPA067561: AB_2685861" "unprognostic (2.20e-1)" "unprognostic (3.75e-1)" "unprognostic (3.18e-1)" "unprognostic (3.23e-2)" "unprognostic (5.11e-2)" "unprognostic (1.72e-3)" "unprognostic (2.30e-2)" "unprognostic (3.62e-3)" "unprognostic (2.76e-2)" "unprognostic (3.48e-1)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 AP2M1 "AP50, CLAPM1, mu2" ENSG00000161203 "Adaptor related protein complex 2 subunit mu 1" Q96CW1 3 184174689-184184091 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036849, HPA069870" Uncertain Supported "Plasma membrane" NA NA 7500 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA036849: AB_10672101, HPA069870: AB_2686217" "unprognostic (1.16e-1)" "unprognostic (1.35e-2)" "unprognostic (5.28e-3)" "unprognostic (4.96e-3)" "unprognostic (1.79e-1)" "unprognostic (2.88e-2)" "prognostic unfavorable (9.12e-4)" "unprognostic (3.80e-3)" "unprognostic (2.09e-1)" "unprognostic (5.53e-2)" "unprognostic (4.11e-2)" "unprognostic (9.18e-2)" "prognostic unfavorable (7.45e-6)" "unprognostic (2.61e-2)" "unprognostic (4.09e-2)" "unprognostic (1.60e-2)" "unprognostic (1.28e-1)" 191.8 364.2 233.5 164.7 250.3 231.3 164.6 211.3 257.3 222.8 196.3 232.4 167.5 216.4 104.2 218.1 178.6 166.5 366.2 261.1 249.0 196.0 140.9 180.0 148.2 234.8 211.1 198.6 106.4 224.8 224.9 243.3 248.9 183.2 141.1 230.4 167.2 231.8 181.2 157.2 156.2 243.7 200.9 162.5 156.3 106.4 235.4 158.4 148.0 194.0 157.6 223.7 192.4 225.6 436.3 327.5 275.7 311.8 432.1 450.8 284.3 714.3 412.5 788.5 550.5 355.1 309.9 198.2 851.3 1076.1 516.1 480.0 376.3 482.9 647.1 409.8 470.4 512.2 365.8 317.9 508.9 254.8 311.5 577.0 269.4 501.1 318.5 711.0 595.3 258.3 250.0 377.1 750.1 993.6 330.1 151.2 674.1 388.1 484.7 302.7 351.5 393.7 489.7 389.3 292.0 212.6 561.3 696.4 335.1 427.5 934.4 305.7 645.0 497.1 400.1 492.4 960.2 336.9 318.7 441.6 937.1 369.9 331.7 194.4 294.8 244.9 137.5 238.8 136.2 114.3 127.6 134.0 268.7 112.7 107.7 111.8 127.7 170.2 206.8 134.1 185.4 441.0 233.5 250.3 211.3 257.3 261.1 249.0 234.8 211.1 248.9 200.9 235.4 225.6 146.8 54.5 50.7 41.4 84.8 124.9 177.2 275.1 97.9 174.2 108.0 98.2 195.9 112.9 133.5 114.0 70.9 400.9 117.3 155.9 375.6 243.7 326.6 69.3 131.2 172.2 140.8 277.8 62.0 161.3 327.1 161.5 71.4 78.5 149.1 173.6 182.4 78.0 576.9 277.6 63.4 119.0 201.4 137.1 162.9 347.8 164.7 185.1 199.3 34.7 369.4 199.4 130.7 26.2 46.1 232.1 153.1 214.8 100.2 138.8 253.8 290.7 58.3 125.9 197.2 106.9 278.0 83.3 101.7 128.5 126.6 513.6 102.6 278.1 154.1 185.1 AP3M1 ENSG00000185009 "Adaptor related protein complex 3 subunit mu 1" Q9Y2T2 10 74120255-74150842 "Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 266.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045591, HPA048380" Uncertain NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA045591: AB_2679377, HPA048380: AB_2680379" "unprognostic (1.83e-3)" "unprognostic (1.26e-1)" "unprognostic (6.69e-2)" "unprognostic (7.52e-2)" "unprognostic (3.40e-2)" "unprognostic (1.61e-1)" "unprognostic (4.92e-3)" "unprognostic (1.04e-1)" "unprognostic (1.07e-1)" "unprognostic (2.10e-1)" "unprognostic (2.24e-1)" "unprognostic (6.99e-2)" "unprognostic (9.64e-2)" "unprognostic (1.55e-1)" "unprognostic (1.68e-1)" "unprognostic (3.84e-1)" "unprognostic (3.43e-2)" 24.6 23.3 9.8 22.6 11.2 16.3 22.5 13.2 13.6 21.3 11.9 21.8 20.7 23.2 16.5 25.6 20.0 18.0 21.5 9.9 13.6 19.7 27.1 19.2 25.6 12.8 15.1 20.0 24.1 36.0 9.0 32.4 13.6 26.1 27.5 17.6 19.0 22.7 14.3 17.3 19.1 29.0 12.3 21.8 20.4 17.6 11.2 30.5 24.5 20.6 32.8 25.7 14.5 14.5 51.8 52.3 64.8 74.3 41.9 56.3 44.1 50.9 65.1 61.1 67.8 60.1 45.9 52.2 34.0 49.2 35.2 55.0 76.7 48.3 74.6 51.8 55.4 43.6 39.4 35.8 34.9 72.9 43.5 40.0 27.5 52.7 43.6 66.9 81.8 43.5 84.9 63.2 55.2 28.2 70.0 34.0 28.2 56.6 266.0 61.9 52.4 41.7 46.1 40.4 30.5 47.5 40.2 102.5 57.3 52.5 97.6 41.3 60.5 31.0 44.5 40.1 60.4 33.3 62.2 75.0 51.1 80.7 31.3 38.1 22.5 16.9 20.5 24.4 23.6 19.9 18.1 21.5 24.5 18.6 18.9 20.1 13.8 23.5 29.3 15.6 19.3 23.2 9.8 11.2 13.2 13.6 9.9 13.6 12.8 15.1 13.6 12.3 11.2 14.5 11.5 28.9 12.1 8.8 19.7 11.0 13.3 10.6 18.8 8.2 17.8 12.2 8.6 11.5 17.3 11.0 33.3 38.3 27.8 15.4 7.9 14.1 2.0 16.8 15.1 15.9 12.0 12.4 16.7 15.7 16.8 15.3 18.3 23.6 12.7 20.9 14.3 19.5 21.1 21.9 15.2 17.6 8.2 19.8 8.2 2.0 17.4 17.4 10.6 8.4 23.1 17.3 17.5 18.6 13.7 15.8 10.2 13.9 18.6 13.6 12.3 10.6 5.8 14.5 19.7 12.7 19.4 19.9 14.7 23.6 13.5 34.2 19.2 20.1 15.4 12.9 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 ARF1 ENSG00000143761 "ADP ribosylation factor 1" P84077 1 228082660-228099212 "Disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB007742 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Cytosol "Plasma membrane" "CAB007742: AB_562043" "unprognostic (9.54e-2)" "unprognostic (1.35e-2)" "unprognostic (2.30e-2)" "unprognostic (2.50e-3)" "unprognostic (2.33e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (4.65e-2)" "unprognostic (1.78e-1)" "unprognostic (3.73e-1)" "unprognostic (8.95e-3)" "unprognostic (6.74e-2)" "unprognostic (2.96e-2)" "unprognostic (5.85e-2)" "unprognostic (2.69e-2)" "unprognostic (1.56e-1)" "unprognostic (8.57e-2)" "unprognostic (1.94e-1)" 268.3 282.5 213.8 176.7 222.5 426.9 241.9 188.1 261.9 249.1 215.1 259.8 242.6 266.6 193.1 304.7 247.5 189.2 340.0 242.7 231.3 257.0 324.7 298.2 185.0 200.6 201.6 237.3 327.6 296.9 299.1 276.9 207.6 244.0 177.3 96.7 355.2 203.9 330.9 237.3 240.8 176.2 196.6 251.4 265.6 193.9 218.9 184.4 240.3 206.4 154.7 229.0 233.1 206.4 476.6 321.6 257.4 257.9 289.9 362.6 425.7 409.5 433.0 444.3 386.8 383.6 442.7 239.9 428.8 438.3 204.6 298.8 316.4 399.4 219.4 355.3 506.8 234.3 209.8 386.6 559.5 342.1 333.8 350.4 476.7 408.6 427.0 374.1 443.3 267.0 456.0 533.3 431.4 341.8 350.0 495.9 331.7 656.7 643.0 279.0 228.1 750.6 315.1 242.1 362.6 320.0 265.9 790.0 466.8 87.8 543.9 681.0 406.0 324.6 256.5 479.4 626.8 498.5 301.0 331.1 445.9 285.0 670.6 1003.7 556.5 625.5 387.3 527.8 472.4 276.7 328.0 359.8 423.6 261.3 253.2 280.8 863.6 345.5 528.2 571.4 417.9 1082.4 213.8 222.5 188.1 261.9 242.7 231.3 200.6 201.6 207.6 196.6 218.9 206.4 276.9 173.1 185.2 25.8 205.1 262.6 281.7 248.0 104.2 114.3 209.1 172.0 139.8 125.8 208.1 115.8 45.9 373.7 267.8 487.8 230.9 422.7 236.3 164.6 218.7 247.2 230.1 173.8 42.3 404.5 565.8 227.3 142.8 240.8 198.3 128.8 152.4 124.8 409.4 158.2 41.1 436.9 213.6 198.8 256.2 429.9 229.2 300.1 300.6 35.6 356.0 162.2 214.2 30.7 40.7 400.2 407.2 227.2 282.8 344.6 370.1 173.3 180.7 80.2 230.1 149.6 416.0 321.1 155.7 158.3 286.0 676.7 224.9 174.6 335.2 370.0 ARMC1 "Arcp, FLJ10511" ENSG00000104442 "Armadillo repeat containing 1" Q9NVT9 8 65602458-65634217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026085 Approved Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA026085: AB_1845031" "prognostic unfavorable (4.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (8.18e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (7.73e-4)" "unprognostic (4.13e-2)" "unprognostic (7.49e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.81e-1)" "unprognostic (3.30e-3)" "unprognostic (1.08e-1)" "unprognostic (1.07e-1)" "unprognostic (1.98e-1)" "unprognostic (1.66e-1)" 16.6 15.4 19.0 13.5 23.8 13.1 18.4 21.0 29.0 15.2 16.4 16.4 15.6 18.6 16.4 16.8 13.2 11.9 21.6 19.7 21.7 22.0 23.2 12.4 19.3 19.8 20.9 18.8 14.9 21.0 9.0 15.0 20.4 17.8 16.6 12.5 15.7 16.9 19.2 11.5 13.7 21.6 20.4 13.9 13.6 9.4 20.8 22.3 14.7 24.6 20.3 16.8 10.8 25.6 51.3 35.6 34.2 32.0 33.1 30.1 24.8 44.7 33.2 46.5 34.2 26.5 40.3 79.0 11.2 41.0 50.7 33.4 61.9 35.9 62.9 45.0 31.7 61.3 20.6 38.9 44.1 23.4 32.0 27.8 40.9 38.3 52.5 36.6 48.5 55.3 64.5 54.7 50.6 32.9 86.9 30.7 35.7 63.6 38.9 49.9 42.6 27.9 37.2 23.8 25.3 27.3 28.5 35.4 44.3 34.6 56.9 27.2 28.5 43.8 32.1 33.8 42.5 40.3 45.2 53.2 41.5 42.8 43.7 36.3 5.6 7.4 8.3 9.3 11.4 9.8 9.9 10.2 7.2 6.9 9.9 10.1 0.7 11.5 9.2 6.4 11.4 6.5 19.0 23.8 21.0 29.0 19.7 21.7 19.8 20.9 20.4 20.4 20.8 25.6 26.6 41.7 27.7 16.0 33.0 15.8 12.1 17.5 19.4 23.7 20.7 19.4 33.4 18.6 24.5 16.5 22.9 35.0 32.9 14.4 54.8 28.3 10.4 15.9 26.9 23.7 23.4 62.7 23.9 28.1 43.9 24.4 20.4 15.3 10.8 31.5 21.4 25.6 25.0 20.2 22.7 17.0 24.4 18.9 12.6 5.7 26.1 20.6 21.4 19.7 31.6 47.3 24.7 15.1 47.7 28.0 13.0 33.4 27.2 18.9 19.9 47.7 17.6 21.9 6.6 29.0 32.2 50.7 24.5 29.9 18.5 37.6 28.0 28.1 23.4 9.1 ASMT "ASMTY, HIOMT, HIOMTY" ENSG00000196433 "Acetylserotonin O-methyltransferase" P46597 X 1615059-1643081 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Melatonin biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.8;Early spermatids: 1.1;Excitatory neurons: 1.5;Extravillous trophoblasts: 1.0;Inhibitory neurons: 1.3;Oligodendrocytes: 1.3;Theca cells: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.84e-2)" "unprognostic (1.63e-3)" "unprognostic (1.89e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-1)" "unprognostic (8.55e-4)" "unprognostic (1.54e-1)" "unprognostic (2.27e-2)" "unprognostic (4.30e-3)" "unprognostic (1.56e-1)" "unprognostic (1.43e-3)" "unprognostic (2.64e-1)" "unprognostic (4.04e-3)" "unprognostic (1.49e-1)" "unprognostic (3.27e-2)" "unprognostic (2.23e-1)" "unprognostic (2.79e-3)" 0.4 0.8 0.6 0.3 0.6 0.7 0.4 0.6 0.9 0.8 1.4 0.5 0.0 0.6 1.8 0.2 0.5 0.2 0.4 0.6 1.1 0.3 0.3 0.3 0.2 0.4 0.4 0.4 0.4 0.1 1.4 0.1 0.4 0.5 0.0 0.4 0.3 0.2 0.2 0.4 0.4 0.2 0.3 0.6 0.4 0.4 0.5 0.1 0.5 0.1 0.1 0.5 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.6 0.0 2.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.9 0.6 1.1 0.4 0.4 0.4 0.3 0.5 0.6 0.2 0.0 1.8 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.2 0.0 0.0 1.5 0.0 1.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.0 0.0 0.1 0.5 3.4 0.0 0.1 ASNS ENSG00000070669 "Asparagine synthetase (glutamine-hydrolyzing)" P08243 7 97851677-97872542 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Asparagine biosynthesis" Ligase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 121.4" "Cell type enhanced" "Detected in all" "Early spermatids: 233.9;Late spermatids: 217.0;Smooth muscle cells: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 8.9;T-cells: 14.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004924, HPA029318, HPA064737" Approved Enhanced Cytosol No No 47000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA004924: AB_2667295, HPA029318: AB_10602389, HPA064737: AB_2685341" "unprognostic (3.93e-2)" "unprognostic (2.51e-1)" "unprognostic (6.70e-2)" "prognostic unfavorable (4.24e-4)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.79e-5)" "prognostic unfavorable (9.42e-6)" "unprognostic (2.28e-2)" "unprognostic (9.08e-2)" "unprognostic (1.89e-1)" "unprognostic (8.10e-3)" "unprognostic (2.53e-3)" "prognostic unfavorable (6.21e-7)" "unprognostic (5.33e-1)" "unprognostic (2.15e-1)" "unprognostic (6.21e-2)" "unprognostic (1.33e-1)" 17.3 18.0 49.9 19.5 52.3 13.7 17.8 52.7 66.3 19.9 28.2 24.5 9.7 19.0 31.5 27.0 20.1 11.2 19.4 55.3 51.0 28.9 9.3 25.6 28.8 58.7 43.5 20.8 121.4 26.3 44.1 4.6 59.4 21.5 19.9 35.3 41.6 14.5 8.0 22.9 22.6 18.0 43.6 30.3 46.0 33.3 49.7 13.3 27.5 8.6 25.7 21.7 18.6 63.8 124.6 46.6 51.6 415.9 35.3 57.9 109.1 85.7 62.5 41.6 134.8 64.2 49.3 101.7 45.3 189.8 92.3 57.4 118.2 151.2 102.2 122.4 85.3 31.0 24.6 50.8 347.8 207.1 89.9 106.2 508.8 55.8 361.2 23.5 41.4 94.4 177.1 365.2 76.3 286.5 6.4 54.4 68.1 308.4 125.4 14.0 10.0 282.7 28.4 22.3 218.1 156.7 23.2 136.7 499.0 60.6 57.1 139.1 7.6 21.6 138.5 56.7 40.7 412.6 239.7 401.1 288.7 90.3 220.8 1.9 0.3 0.4 3.6 1.1 4.3 8.9 7.2 3.4 1.5 6.0 10.1 5.5 1.8 2.0 1.0 0.2 14.2 3.3 49.9 52.3 52.7 66.3 55.3 51.0 58.7 43.5 59.4 43.6 49.7 63.8 5.8 9.6 7.2 11.1 14.4 12.4 26.1 20.9 6.2 20.3 9.7 11.2 7.6 7.2 12.3 9.2 25.0 3.1 6.7 10.5 7.9 30.9 233.9 2.9 8.6 6.7 24.4 46.1 51.8 61.6 7.8 8.9 14.3 4.5 8.2 8.8 2.9 1.3 1.1 25.2 48.6 19.6 32.6 1.3 3.2 217.0 9.6 2.1 8.8 5.6 7.3 9.2 5.2 16.1 16.9 36.6 14.7 9.4 19.9 26.1 1.1 3.9 4.5 24.9 6.6 10.2 112.3 3.4 20.2 5.5 10.9 5.6 11.2 6.0 9.9 14.9 ASNSD1 "FLJ20752, NBLA00058, NS3TP1" ENSG00000138381 "Asparagine synthetase domain containing 1" Q9NWL6 2 189661385-189670831 "Predicted intracellular proteins" "Amino-acid biosynthesis, Asparagine biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036132, HPA036133, HPA075042" Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA036132: AB_2674960, HPA036133: AB_10696650, HPA075042: AB_2686731" "unprognostic (1.32e-1)" "unprognostic (1.70e-1)" "unprognostic (4.88e-2)" "unprognostic (2.15e-3)" "prognostic favorable (4.54e-4)" "unprognostic (8.42e-2)" "prognostic unfavorable (8.66e-4)" "unprognostic (5.68e-2)" "unprognostic (1.35e-2)" "unprognostic (1.41e-3)" "unprognostic (2.09e-1)" "unprognostic (6.32e-3)" "unprognostic (8.98e-3)" "unprognostic (8.11e-2)" "unprognostic (2.52e-1)" "unprognostic (1.53e-1)" "unprognostic (1.86e-1)" 27.1 26.1 23.1 19.2 24.5 36.9 33.5 31.8 33.5 27.9 21.3 21.1 22.5 28.6 19.6 21.3 24.0 19.7 32.2 23.6 25.5 30.5 40.4 21.9 27.1 24.2 24.0 37.6 27.1 33.2 19.1 33.7 24.5 21.6 18.3 40.2 25.2 20.8 59.6 17.5 17.7 28.1 24.6 23.0 20.4 17.5 24.1 27.9 26.3 70.5 25.1 27.4 17.1 25.9 33.1 22.0 53.5 42.5 58.9 50.4 47.2 66.4 57.1 65.7 67.5 72.5 22.6 65.3 39.0 61.9 36.4 26.5 60.2 49.2 76.6 65.4 72.5 57.5 48.5 69.2 61.4 59.9 33.2 59.9 37.2 66.3 58.9 46.5 63.3 46.9 58.6 49.6 69.6 43.2 68.8 68.9 81.0 55.3 102.4 41.3 43.4 62.4 39.0 40.2 59.5 31.2 41.7 35.0 59.1 66.7 52.3 55.9 57.0 56.6 44.5 48.1 73.4 73.7 86.5 93.4 44.1 33.9 52.7 82.8 26.1 107.6 38.8 22.7 48.6 37.2 42.3 43.3 26.7 37.2 49.4 45.3 48.9 49.1 25.2 21.4 57.6 37.3 23.1 24.5 31.8 33.5 23.6 25.5 24.2 24.0 24.5 24.6 24.1 25.9 31.3 54.5 34.9 10.1 41.1 30.0 24.4 31.2 25.0 22.4 29.7 25.9 43.7 28.6 35.6 16.5 12.5 67.2 36.1 24.1 82.2 35.7 7.0 24.8 34.9 31.1 36.0 41.7 17.2 45.3 43.3 41.8 16.8 22.8 19.0 24.6 29.6 51.9 34.1 15.2 18.9 25.2 26.4 28.0 23.7 5.6 40.7 24.5 17.8 7.5 34.7 40.5 50.4 14.6 17.6 36.5 12.0 33.8 37.9 23.0 18.7 56.7 29.4 27.0 46.0 48.7 47.9 30.3 43.8 29.4 28.4 119.9 42.7 30.9 27.7 19.3 ATG3 "APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96" ENSG00000144848 "Autophagy related 3" Q9NT62 3 112532510-112562046 "Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 657.9;Spermatocytes: 341.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037260, HPA040471" Enhanced Supported "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB037260: AB_1078236, HPA040471: AB_2677000" "unprognostic (2.77e-2)" "prognostic favorable (6.82e-4)" "unprognostic (4.90e-3)" "unprognostic (1.30e-1)" "unprognostic (2.63e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (9.35e-6)" "unprognostic (6.79e-2)" "unprognostic (6.67e-2)" "unprognostic (6.99e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.52e-3)" "unprognostic (4.66e-2)" "unprognostic (6.02e-2)" "unprognostic (3.48e-2)" "unprognostic (5.25e-2)" 33.1 38.7 41.4 49.1 50.1 94.1 34.7 51.3 53.5 28.3 38.2 38.2 38.2 24.7 24.7 34.8 23.2 24.7 33.3 39.7 46.8 41.6 43.3 31.1 48.4 49.1 48.2 25.6 41.8 44.8 30.6 33.6 48.5 23.2 40.3 29.1 29.4 28.3 29.5 29.8 36.6 29.9 48.2 48.2 37.7 85.3 45.6 51.2 42.2 33.6 46.3 38.7 26.3 55.7 105.0 55.9 51.5 52.6 66.6 54.5 57.5 89.8 65.3 86.9 78.9 78.9 60.6 130.3 66.6 78.0 106.6 74.1 84.9 78.0 120.9 22.8 40.9 82.0 52.3 51.0 102.9 145.2 67.0 50.6 58.3 85.5 130.2 56.8 82.2 81.2 71.6 108.8 92.9 91.4 86.4 68.2 56.3 135.8 109.7 74.9 45.9 110.5 72.6 56.1 88.1 34.7 74.7 70.5 109.5 48.4 79.8 107.5 66.7 92.3 75.8 39.4 80.1 70.2 72.0 201.3 84.4 133.2 69.4 64.4 167.7 121.9 39.4 258.8 49.4 61.8 48.0 49.2 169.4 59.2 46.2 46.3 174.2 50.5 327.9 36.3 75.6 138.2 41.4 50.1 51.3 53.5 39.7 46.8 49.1 48.2 48.5 48.2 45.6 55.7 45.6 48.1 39.0 10.1 53.3 74.1 42.4 74.3 37.5 22.5 32.0 50.2 86.2 37.1 51.3 25.8 12.5 73.1 45.3 47.0 117.4 73.7 657.9 37.9 40.8 54.1 31.2 90.0 11.7 86.1 85.0 42.6 36.7 45.2 39.9 42.0 40.0 40.0 121.3 18.5 11.4 53.3 75.3 106.3 131.1 146.5 42.6 134.8 69.4 11.2 185.8 42.1 54.6 13.0 33.7 70.9 49.2 43.2 70.4 39.1 76.0 87.5 37.3 22.2 59.2 45.5 77.6 341.0 119.7 57.4 70.6 122.3 55.0 68.6 69.8 54.2 ATP2B3 "CFAP39, CLA2, PMCA3, SCAX1" ENSG00000067842 "ATPase plasma membrane Ca2+ transporting 3" Q16720 X 153517676-153582939 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "choroid plexus: 187.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.1;Endometrial ciliated cells: 6.5;Excitatory neurons: 23.7;Extravillous trophoblasts: 10.7;Inhibitory neurons: 30.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 9.9;SH-SY5Y: 2.9;THP-1: 2.5;U-937: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001583 Enhanced Supported NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 10: Non-specific - Unknown function" "HPA001583: AB_1079641" "unprognostic (1.35e-1)" "unprognostic (3.07e-2)" "unprognostic (3.28e-1)" "unprognostic (6.82e-2)" "unprognostic (1.30e-1)" "unprognostic (4.32e-2)" "unprognostic (2.67e-1)" "unprognostic (6.34e-2)" "unprognostic (2.68e-2)" "unprognostic (8.58e-2)" "unprognostic (1.38e-3)" "unprognostic (3.44e-1)" "unprognostic (2.71e-12)" "unprognostic (1.44e-3)" "unprognostic (2.04e-1)" "unprognostic (2.42e-2)" 0.0 9.7 6.0 0.0 7.5 0.0 0.0 3.4 33.7 0.0 187.9 0.3 0.0 0.0 0.9 0.0 1.2 0.0 0.0 25.7 1.3 0.2 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 1.4 0.5 4.8 0.0 0.0 2.2 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 2.9 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 7.5 3.4 33.7 25.7 1.3 5.5 0.0 4.8 0.0 2.7 12.2 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 1.3 0.1 0.0 0.0 23.7 0.0 10.7 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 30.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.4 0.0 3.5 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.6 4.5 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 ATP6V0B "ATP6F, HATPL, VMA16" ENSG00000117410 "ATPase H+ transporting V0 subunit b" Q99437 1 43974487-43978295 "Metabolic proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 1694.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2268.9" "Group enriched" "Detected in all" 4 "dendritic cells: 769.4;granulocytes: 2268.9;monocytes: 1046.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044281 Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA044281: " "unprognostic (1.38e-1)" "unprognostic (2.16e-1)" "unprognostic (1.27e-1)" "unprognostic (5.69e-2)" "unprognostic (5.31e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (4.79e-4)" "unprognostic (1.32e-1)" "unprognostic (1.82e-2)" "unprognostic (7.23e-2)" "prognostic favorable (3.24e-4)" "unprognostic (6.13e-2)" "prognostic favorable (3.62e-6)" "unprognostic (5.55e-2)" "unprognostic (1.93e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (8.87e-4)" 78.9 162.2 222.2 68.3 225.4 286.4 79.4 234.5 267.0 63.8 253.8 94.8 61.1 57.5 97.3 101.0 61.5 64.5 107.2 231.3 256.2 233.8 168.3 115.8 71.6 235.4 232.9 49.7 172.0 182.0 157.5 76.6 251.1 101.4 90.8 106.6 112.1 60.7 138.6 98.9 83.8 55.7 232.2 143.7 124.9 56.7 244.0 60.1 101.7 84.0 74.7 92.6 70.9 255.4 150.4 135.9 99.4 129.1 149.3 78.0 142.9 134.1 168.5 217.1 183.6 143.2 144.5 140.3 119.7 119.0 253.2 118.4 233.4 170.1 99.8 135.4 266.4 175.0 209.7 195.1 238.0 262.7 307.9 97.4 219.6 235.3 206.5 136.7 105.1 167.3 189.5 260.9 177.1 147.3 103.2 411.3 182.4 184.8 271.1 150.7 108.1 371.7 225.2 159.1 260.9 137.2 89.0 303.1 319.0 111.4 128.8 419.5 62.8 119.0 105.7 222.6 311.4 241.9 397.5 150.3 161.2 355.5 188.5 528.7 1046.6 892.1 161.2 652.9 161.5 321.1 171.0 156.8 630.7 271.9 129.7 130.1 2268.9 124.4 618.8 769.4 187.2 1450.9 222.2 225.4 234.5 267.0 231.3 256.2 235.4 232.9 251.1 232.2 244.0 255.4 125.1 80.1 126.9 26.4 176.6 335.9 161.9 577.2 173.6 238.7 241.5 219.1 101.7 144.4 367.7 283.3 102.2 197.4 216.0 242.1 201.5 347.8 4.4 186.6 93.6 136.9 224.0 114.6 36.5 328.5 223.3 118.9 114.7 207.9 206.7 77.0 102.1 241.0 815.7 129.5 40.5 306.2 1694.7 347.6 454.5 12.9 78.9 489.8 281.1 24.4 379.2 220.2 103.0 28.6 62.4 379.0 382.7 65.5 301.2 355.1 186.0 223.5 244.1 231.7 78.9 77.4 444.3 116.6 197.9 192.9 358.3 496.5 121.2 135.9 241.8 337.5 ATP6V1C1 "ATP6C, ATP6D, VATC, Vma5" ENSG00000155097 "ATPase H+ transporting V1 subunit C1" P21283 8 103021063-103073051 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 162.7;Late spermatids: 166.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023943, HPA057297" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA023943: AB_1845197, HPA057297: AB_2683402" "unprognostic (5.73e-3)" "unprognostic (3.30e-1)" "unprognostic (1.09e-2)" "unprognostic (1.93e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-2)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.29e-2)" "unprognostic (3.87e-1)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (5.59e-2)" "unprognostic (3.98e-2)" "unprognostic (1.23e-1)" "unprognostic (3.85e-1)" "unprognostic (3.88e-1)" "unprognostic (2.83e-1)" 23.8 32.2 31.6 23.8 36.8 9.7 21.6 18.7 38.2 17.8 20.7 15.4 16.1 19.0 14.2 15.6 16.8 19.8 30.1 39.4 28.9 51.7 27.5 18.6 26.2 25.4 24.5 17.7 18.8 39.0 22.2 30.2 31.5 18.3 18.8 36.7 15.3 16.1 17.2 11.9 17.8 20.6 20.2 19.9 17.4 20.9 25.5 21.9 37.8 24.3 24.5 25.2 14.0 26.3 68.4 38.6 20.2 15.6 54.6 39.3 27.7 49.0 49.7 60.6 68.9 30.4 76.7 41.2 58.2 40.8 97.5 29.6 42.4 41.0 87.8 30.3 26.4 39.2 28.0 35.8 59.5 20.8 52.5 28.8 55.4 77.4 36.2 35.6 43.9 28.7 54.6 37.3 71.4 32.1 46.2 16.7 19.1 67.9 37.6 24.6 36.0 36.4 70.3 48.8 28.5 22.6 26.9 26.9 102.0 40.5 58.9 27.8 44.4 33.2 36.1 74.3 35.0 45.1 17.7 42.1 60.2 47.2 33.2 16.8 30.5 38.1 15.1 44.9 17.2 18.7 12.7 15.1 29.0 18.7 14.4 16.0 50.2 18.7 42.7 15.8 23.1 21.1 31.6 36.8 18.7 38.2 39.4 28.9 25.4 24.5 31.5 20.2 25.5 26.3 31.3 32.1 26.4 38.2 22.9 34.9 33.1 31.2 21.1 32.3 21.9 20.6 43.3 15.7 26.5 31.3 16.7 35.4 15.5 14.7 64.6 36.9 162.7 18.3 19.5 25.5 15.6 33.6 64.9 31.5 35.6 28.4 12.2 16.4 24.1 14.0 17.5 19.0 101.8 37.0 56.6 12.4 46.8 47.6 99.6 166.9 24.2 62.8 19.6 36.5 34.3 34.5 14.4 39.2 44.7 30.4 18.2 18.4 25.1 34.7 19.2 139.1 41.2 25.3 19.7 20.7 45.5 11.1 23.4 19.5 32.8 74.8 18.5 17.4 13.5 27.4 ATXN7L2 "FLJ00381, MGC46534" ENSG00000162650 "Ataxin 7 like 2" Q5T6C5 1 109483479-109492804 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 7.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029827, HPA054952" Uncertain Approved "Nucleoli rim,Vesicles,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoli rim" "Vesicles, Cytosol" "HPA029827: AB_10602390, HPA054952: AB_2682647" "unprognostic (4.53e-2)" "unprognostic (6.55e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.65e-4)" "unprognostic (3.90e-2)" "unprognostic (4.61e-5)" "unprognostic (2.40e-4)" "unprognostic (1.75e-1)" "unprognostic (3.53e-2)" "unprognostic (8.07e-2)" "unprognostic (2.77e-4)" "unprognostic (2.85e-2)" "prognostic unfavorable (1.19e-8)" "unprognostic (3.70e-2)" "unprognostic (1.08e-1)" "unprognostic (8.27e-2)" "unprognostic (3.94e-3)" 1.2 2.7 1.3 0.7 1.4 3.0 1.1 1.3 2.7 1.9 0.7 1.2 0.5 2.0 0.1 1.2 1.4 0.8 1.3 2.5 1.0 2.0 1.7 1.0 0.9 1.1 1.1 1.9 1.0 0.3 2.1 0.4 1.0 1.2 0.1 0.1 0.9 0.4 7.9 1.7 1.4 0.3 0.9 2.2 1.0 5.2 1.3 1.5 2.2 1.6 0.5 1.3 1.2 1.4 1.8 1.4 0.9 3.6 1.2 2.2 2.5 1.3 1.6 2.6 1.8 3.0 1.2 4.8 2.0 1.6 0.7 2.1 1.9 1.8 0.3 4.4 2.7 2.6 3.0 1.3 0.8 4.0 6.0 2.4 0.9 2.8 0.0 1.1 0.6 5.1 4.5 2.6 0.5 5.8 7.1 5.2 5.6 1.9 2.0 4.9 2.3 3.4 0.9 1.9 8.4 3.4 1.4 4.5 2.2 0.2 0.8 4.1 0.3 1.9 5.5 1.8 5.3 1.7 1.2 4.6 2.2 3.3 4.8 0.0 0.8 1.1 2.3 1.1 2.2 1.0 1.9 2.5 0.6 1.3 1.7 1.6 0.9 1.4 0.8 0.4 1.8 1.0 1.3 1.4 1.3 2.7 2.5 1.0 1.1 1.1 1.0 0.9 1.3 1.4 1.0 0.0 0.5 5.5 2.4 0.6 1.4 1.3 1.8 3.5 1.4 0.9 1.9 1.5 2.1 1.8 2.1 1.4 1.6 1.4 0.0 1.4 3.5 0.8 2.4 1.3 1.8 0.8 4.7 1.8 1.5 1.7 1.1 1.0 4.5 2.3 1.8 1.1 0.6 3.3 3.9 1.1 2.0 1.2 1.0 1.0 1.2 0.6 0.0 1.0 0.4 0.9 1.0 3.0 1.8 1.5 1.4 1.5 2.9 0.7 0.7 0.6 0.3 2.0 0.0 2.5 4.8 4.2 4.9 1.3 0.9 3.1 2.6 3.5 0.9 0.9 ATXN7L3 DKFZp761G2113 ENSG00000087152 "Ataxin 7 like 3" Q14CW9 17 44191805-44200113 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064316 Supported Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Plasma membrane" "HPA064316: AB_2685243" "unprognostic (2.37e-2)" "unprognostic (8.87e-3)" "unprognostic (1.10e-1)" "unprognostic (3.74e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.03e-4)" "unprognostic (2.86e-3)" "unprognostic (6.74e-3)" "unprognostic (1.09e-1)" "unprognostic (1.50e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.21e-3)" "unprognostic (9.05e-2)" "unprognostic (3.75e-2)" "unprognostic (1.40e-1)" 23.3 24.6 51.0 32.6 58.1 45.0 21.3 28.0 76.6 28.4 12.0 26.8 31.2 28.3 25.9 40.1 26.5 24.1 24.9 58.5 35.9 29.2 28.0 25.2 37.2 58.3 42.4 25.5 24.2 24.5 35.1 30.7 60.6 26.9 24.3 21.5 27.9 27.7 25.3 31.2 29.6 25.8 33.0 36.3 28.3 36.9 48.3 42.1 29.1 22.6 35.5 28.7 28.1 54.1 40.9 67.7 73.3 47.8 50.1 49.5 39.8 49.1 54.3 61.4 57.7 52.0 45.1 71.3 38.6 55.5 56.6 43.9 57.7 46.1 51.2 83.6 57.2 48.5 58.9 58.5 49.3 76.3 94.3 56.1 69.0 51.7 54.1 65.0 60.3 54.2 66.1 43.5 40.8 30.7 92.3 58.0 55.1 36.7 52.5 62.8 70.9 54.1 49.8 57.9 46.5 59.0 29.0 25.4 50.5 101.4 62.0 67.1 52.2 61.5 63.8 32.3 46.5 52.1 73.8 86.4 40.6 32.6 36.8 0.4 1.2 1.5 1.7 0.7 1.0 1.4 1.4 1.1 1.0 2.4 1.0 1.3 2.5 0.5 0.9 1.6 0.8 1.1 51.0 58.1 28.0 76.6 58.5 35.9 58.3 42.4 60.6 33.0 48.3 54.1 14.3 3.2 3.7 5.5 9.4 7.1 5.6 8.0 8.6 17.4 13.7 9.1 6.2 5.7 6.6 18.4 16.7 6.3 11.3 22.2 3.9 7.1 14.7 14.0 16.9 10.5 14.4 4.0 9.1 13.1 6.7 7.2 8.6 20.7 2.5 9.9 10.4 8.1 8.4 28.6 8.6 11.0 4.1 11.1 10.9 40.0 9.0 10.0 5.4 8.4 12.7 8.6 5.2 3.0 5.3 15.0 13.6 5.7 5.5 8.6 14.1 4.6 7.6 13.9 6.6 6.7 9.3 6.3 8.5 11.0 10.5 13.7 10.0 10.4 11.2 9.1 ATXN7L3B lnc-SCA7 ENSG00000253719 "Ataxin 7 like 3B" Q96GX2 12 74537835-74545430 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056612 Approved Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA056612: AB_2683190" "unprognostic (3.43e-3)" "unprognostic (1.07e-1)" "unprognostic (4.76e-2)" "unprognostic (3.20e-2)" "unprognostic (3.68e-1)" "unprognostic (9.26e-2)" "unprognostic (1.81e-3)" "unprognostic (7.12e-2)" "unprognostic (9.55e-2)" "unprognostic (6.06e-2)" "unprognostic (2.08e-1)" "unprognostic (1.49e-1)" "prognostic favorable (2.25e-6)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (1.16e-2)" "unprognostic (1.15e-2)" 13.8 18.5 27.5 15.2 28.2 20.1 22.2 26.2 30.7 18.2 25.5 17.3 20.3 21.1 25.0 13.9 33.2 14.2 17.9 28.9 32.0 23.6 20.5 16.6 21.0 25.6 27.2 32.3 22.9 25.9 15.9 22.8 28.8 22.3 19.1 46.3 23.3 21.1 20.9 17.9 18.9 18.0 25.3 19.1 38.3 8.8 30.7 30.5 24.5 20.9 22.8 14.1 12.0 27.4 21.5 16.6 54.3 34.6 33.6 31.4 23.2 20.1 20.0 23.3 18.1 19.3 11.6 31.0 15.6 20.0 15.6 21.1 28.4 19.4 19.2 28.8 22.3 41.5 17.3 29.4 32.0 41.6 8.4 36.4 44.3 17.9 29.2 40.6 27.3 35.5 52.1 15.2 19.3 31.0 46.2 29.5 31.0 29.4 15.8 35.7 29.4 28.1 21.5 34.8 85.1 53.7 22.7 26.6 32.6 35.0 62.8 26.9 23.6 22.3 19.5 13.4 12.7 18.0 18.0 39.9 9.6 15.0 22.8 17.3 9.5 12.7 5.1 8.9 6.2 4.2 7.7 5.7 8.9 4.8 13.1 7.4 2.7 8.4 12.1 4.9 6.1 9.1 27.5 28.2 26.2 30.7 28.9 32.0 25.6 27.2 28.8 25.3 30.7 27.4 40.1 73.7 46.3 10.1 33.4 18.4 42.1 25.2 56.9 87.9 40.6 44.7 53.0 41.5 48.3 38.6 33.3 58.7 54.8 33.1 31.3 39.6 0.7 76.1 67.5 39.9 36.2 36.2 17.2 32.8 34.0 41.7 98.4 37.5 46.2 35.8 27.8 27.5 22.9 52.2 18.2 38.7 10.2 23.9 10.7 2.0 37.6 25.9 21.4 13.1 32.9 104.5 62.8 9.5 17.9 61.8 23.4 37.6 27.6 47.3 23.3 39.8 113.5 80.8 19.7 58.8 81.5 11.6 15.8 37.0 22.9 45.0 37.5 46.7 35.8 37.9 BAX BCL2L4 ENSG00000087088 "BCL2 associated X, apoptosis regulator" Q07812 19 48954815-48961798 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004206, HPA027878" Approved NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "CAB004206: AB_626729, HPA027878: AB_10601687" "unprognostic (4.11e-2)" "unprognostic (4.70e-2)" "unprognostic (1.50e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (1.63e-5)" "unprognostic (4.92e-2)" "unprognostic (1.09e-1)" "unprognostic (4.71e-2)" "unprognostic (3.66e-2)" "unprognostic (8.10e-2)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (1.08e-1)" "unprognostic (4.47e-3)" "unprognostic (6.22e-2)" 30.2 30.4 24.4 59.2 26.8 65.7 27.2 25.5 29.3 27.6 23.9 78.1 68.2 29.9 23.2 35.8 33.2 37.6 22.6 24.5 25.5 31.0 33.4 46.0 59.5 27.1 25.4 19.6 32.7 26.1 15.9 43.3 27.0 25.7 58.8 7.2 26.5 27.0 18.1 29.8 64.6 36.3 26.1 60.0 43.8 12.4 26.3 83.2 23.4 11.8 44.7 46.7 26.1 27.1 177.4 286.0 170.1 150.4 165.4 161.7 280.2 117.8 233.4 151.7 210.6 76.4 168.6 214.6 53.9 181.2 141.3 93.8 78.0 229.0 125.7 166.6 181.0 91.9 56.6 288.0 265.7 96.3 280.9 222.3 161.7 126.1 75.5 183.3 354.6 83.4 91.4 86.0 264.8 123.1 157.6 150.3 132.8 171.3 82.5 109.2 113.1 82.4 161.0 168.4 97.4 114.7 99.2 69.8 57.4 240.6 56.2 171.2 210.2 194.0 212.1 120.1 165.1 97.9 136.6 145.0 118.1 129.2 275.1 5.2 12.1 13.4 6.5 18.4 4.6 7.3 3.7 7.1 12.2 5.9 2.4 6.0 13.1 12.2 20.9 12.5 7.5 8.4 24.4 26.8 25.5 29.3 24.5 25.5 27.1 25.4 27.0 26.1 26.3 27.1 83.2 3.2 4.8 8.1 164.6 54.8 63.8 160.8 101.3 19.3 64.1 67.4 8.4 78.6 98.7 60.7 10.4 126.0 130.2 152.9 74.3 122.7 1.1 43.4 65.7 83.7 114.0 79.3 7.9 96.2 157.9 57.0 114.2 46.0 43.9 151.7 59.3 28.1 263.6 30.3 8.3 102.7 209.5 121.8 143.0 4.0 48.1 148.3 83.6 3.7 295.3 43.9 140.1 7.5 13.8 139.4 177.0 38.4 96.2 126.6 229.8 227.4 66.4 15.9 46.0 35.8 259.4 20.3 38.1 92.0 56.4 101.9 149.4 175.5 149.7 86.7 BAZ1B "WBSCR10, WBSCR9, WSTF" ENSG00000009954 "Bromodomain adjacent to zinc finger domain 1B" Q9UIG0 7 73440406-73522293 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037081, CAB037158, HPA058068" Supported Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB037081: AB_477637, CAB037158: AB_477636, HPA058068: " "unprognostic (1.17e-1)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (2.06e-2)" "unprognostic (1.37e-1)" "unprognostic (5.72e-2)" "unprognostic (1.10e-3)" "unprognostic (1.89e-1)" "unprognostic (1.09e-1)" "unprognostic (2.50e-2)" "unprognostic (1.53e-1)" "unprognostic (2.12e-1)" "unprognostic (7.13e-2)" "unprognostic (1.03e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 22.6 19.4 24.1 22.1 28.3 24.7 16.7 28.6 25.2 22.5 21.5 23.0 16.0 24.4 17.7 18.0 19.3 16.0 19.6 21.9 26.9 16.8 24.1 20.3 27.9 25.1 26.5 30.8 21.0 27.6 19.2 22.7 24.7 22.6 20.5 28.3 17.1 25.4 28.0 14.2 18.2 24.7 23.8 23.4 18.9 17.3 25.5 40.6 23.8 30.7 29.6 21.9 17.5 29.1 75.6 76.1 102.5 115.3 52.0 55.1 34.1 71.7 54.7 67.4 70.5 62.4 55.6 141.6 16.3 64.1 102.6 51.7 126.1 47.7 100.9 80.3 63.8 84.4 89.3 54.3 57.9 128.8 68.5 39.6 45.5 83.2 101.6 50.4 54.5 75.9 149.9 86.4 76.7 71.7 132.8 59.1 66.7 57.6 56.2 133.1 89.9 94.5 38.5 58.2 102.4 87.2 102.1 112.4 59.8 87.1 69.1 63.6 64.4 116.1 66.5 70.6 123.2 49.7 84.7 235.7 65.9 119.1 107.7 4.0 1.5 1.0 3.0 1.1 2.6 1.2 2.3 2.2 1.1 2.5 1.7 1.9 1.1 2.8 0.8 3.1 2.5 0.9 24.1 28.3 28.6 25.2 21.9 26.9 25.1 26.5 24.7 23.8 25.5 29.1 46.3 76.9 129.8 28.7 52.8 29.8 34.5 16.7 38.1 69.9 28.1 24.6 81.7 27.1 59.0 20.2 43.8 57.3 50.4 33.1 7.9 35.5 8.4 47.4 72.2 53.5 34.7 89.8 35.0 23.1 59.6 58.7 34.7 52.6 51.8 59.5 34.6 59.1 33.0 60.6 35.3 34.6 22.4 33.4 24.8 12.5 61.2 38.7 12.4 34.7 47.3 54.4 61.8 28.6 43.9 26.5 13.6 76.3 65.3 40.5 25.2 12.9 49.2 53.8 32.9 67.1 57.5 75.7 127.0 47.0 25.3 34.6 56.5 46.1 43.3 35.2 BCCIP "BCCIPalpha, TOK-1" ENSG00000107949 "BRCA2 and CDKN1A interacting protein" Q9P287 10 125823546-125853695 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038011 Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA038011: AB_2675784" "unprognostic (1.05e-1)" "unprognostic (2.38e-2)" "unprognostic (2.29e-1)" "unprognostic (2.96e-2)" "unprognostic (3.54e-2)" "unprognostic (1.38e-2)" "unprognostic (1.93e-3)" "unprognostic (2.51e-1)" "unprognostic (3.04e-2)" "unprognostic (6.62e-3)" "unprognostic (1.88e-1)" "unprognostic (1.30e-3)" "unprognostic (1.90e-3)" "unprognostic (4.75e-2)" "unprognostic (1.58e-1)" "unprognostic (7.39e-2)" "unprognostic (9.91e-2)" 40.0 35.1 37.7 38.3 39.1 62.4 52.4 41.1 43.4 31.4 42.3 37.6 32.3 31.0 54.6 38.5 33.0 26.6 48.0 37.5 38.7 55.3 67.9 27.2 49.3 38.3 38.3 42.8 47.1 41.6 24.8 32.5 39.2 42.4 41.1 55.7 58.2 28.6 77.5 31.8 31.7 31.4 38.7 29.8 42.8 48.3 39.0 50.0 39.8 63.6 48.7 55.9 30.1 40.8 225.6 114.4 126.9 141.3 70.9 77.2 105.9 117.9 112.1 142.3 131.2 188.2 146.4 156.6 72.1 108.6 107.1 121.4 219.3 167.0 197.6 145.3 148.5 157.9 97.5 210.0 89.4 219.7 96.1 79.9 98.7 170.1 178.3 108.0 137.7 145.1 177.7 78.1 122.5 134.7 142.7 220.4 98.2 188.0 170.2 134.7 133.5 94.3 126.6 106.0 67.2 68.5 88.1 142.4 149.9 102.7 76.9 96.3 93.0 65.9 116.9 98.2 215.9 79.3 94.9 233.0 129.7 112.5 52.0 30.3 68.3 41.1 56.2 86.6 77.8 76.8 63.7 61.9 75.2 71.4 71.1 64.4 11.2 68.2 94.3 65.0 75.6 48.1 37.7 39.1 41.1 43.4 37.5 38.7 38.3 38.3 39.2 38.7 39.0 40.8 21.6 64.1 67.9 16.6 46.9 66.9 59.3 60.6 58.1 24.2 32.2 27.3 80.4 28.6 67.0 23.9 22.9 41.4 28.2 16.7 78.2 52.7 14.7 37.6 36.6 30.4 25.8 47.3 21.3 44.1 38.0 43.2 40.2 33.2 27.1 33.6 23.2 50.4 35.8 16.8 21.0 23.1 42.7 28.9 22.2 9.4 37.0 29.3 23.2 11.2 36.2 30.2 28.8 22.1 25.7 45.1 19.6 31.2 57.7 51.9 22.7 62.4 74.7 25.1 26.3 47.5 37.5 105.3 117.2 57.8 52.1 33.8 38.6 28.3 33.3 55.5 BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 38.5;Bipolar cells: 13.8;Cardiomyocytes: 9.1;Excitatory neurons: 22.3;Smooth muscle cells: 25.8;Theca cells: 9.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 36.6;BJ hTERT+ SV40 Large T+: 28.0;BJ hTERT+ SV40 Large T+ RasG12V: 20.9;HBF TERT88: 26.5;U-138 MG: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009564, HPA031440, HPA056104" Enhanced Supported "Nuclear speckles,Mitochondria" "Secreted to blood" NA Yes 16000000 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Mitochondria" "CAB009564: AB_2064213, HPA031440: AB_2673883, HPA056104: AB_2683038" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" 0.4 0.5 1.9 0.2 2.4 0.2 0.2 3.3 5.3 0.6 0.1 0.4 0.3 0.2 3.3 0.6 0.1 0.7 3.6 8.2 1.9 0.6 0.1 2.0 0.1 3.3 2.1 0.5 0.4 0.0 1.2 1.6 2.5 2.0 0.1 0.7 0.3 1.8 0.4 0.9 0.1 0.1 0.4 0.1 0.3 0.6 1.6 0.3 1.0 0.0 0.1 2.1 0.6 0.8 2.9 12.2 0.3 0.0 3.7 2.2 0.0 36.6 7.9 28.0 20.9 0.1 4.0 0.0 3.7 11.8 0.5 1.4 0.1 0.2 26.5 0.2 0.1 0.0 3.5 0.0 17.4 0.2 0.2 9.2 4.2 6.8 3.7 18.1 1.3 0.1 0.0 0.1 4.8 0.0 0.0 0.0 4.0 0.1 2.9 0.0 2.0 0.0 4.5 0.0 0.2 1.1 7.8 0.1 0.1 1.7 0.2 0.0 11.0 37.6 6.9 14.4 9.2 0.5 0.1 0.0 14.1 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.4 3.3 5.3 8.2 1.9 3.3 2.1 2.5 0.4 1.6 0.8 0.2 38.5 0.5 1.6 0.0 0.6 0.4 0.5 1.8 13.8 0.5 0.9 9.1 0.0 0.4 1.8 4.2 0.4 0.0 0.1 0.0 0.8 1.8 0.3 0.3 0.2 0.0 0.0 22.3 0.0 0.5 6.1 0.0 0.1 1.3 1.9 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.4 1.5 0.3 0.9 1.8 0.0 0.0 0.2 0.0 2.0 2.2 0.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 1.8 0.0 1.8 25.8 3.7 0.8 2.3 0.0 0.7 0.0 9.3 0.1 0.1 BMS1 "BMS1L, KIAA0187" ENSG00000165733 "BMS1 ribosome biogenesis factor" Q14692 10 42782795-42834937 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036589, HPA043081" Uncertain Enhanced "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Mitotic chromosome" "HPA036589: AB_10601460, HPA043081: AB_2678305" "unprognostic (1.46e-2)" "unprognostic (4.31e-1)" "unprognostic (7.09e-2)" "unprognostic (3.56e-2)" "unprognostic (3.11e-2)" "unprognostic (7.25e-3)" "prognostic unfavorable (1.06e-6)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (1.89e-2)" "unprognostic (3.81e-3)" "unprognostic (1.32e-2)" "unprognostic (2.16e-3)" "unprognostic (7.03e-2)" "unprognostic (1.80e-1)" "unprognostic (3.43e-1)" "unprognostic (4.82e-2)" 8.1 8.3 6.5 8.9 7.2 10.7 8.5 8.6 8.2 8.2 8.5 7.7 6.3 8.2 6.8 9.6 7.3 5.1 9.0 6.1 7.8 8.1 8.1 7.6 10.0 7.4 7.8 8.4 8.8 11.4 7.6 8.2 7.7 7.3 7.9 6.5 8.8 6.9 17.7 10.2 7.8 7.7 6.5 8.7 7.4 8.1 7.0 9.6 7.2 13.4 10.8 10.1 8.3 7.2 32.0 26.7 25.3 29.0 18.8 15.5 24.5 26.1 27.5 30.3 25.9 37.1 24.4 16.9 18.1 22.7 17.0 27.3 42.0 33.8 39.4 24.7 29.3 22.7 20.7 31.9 16.2 61.7 20.4 13.9 16.9 32.7 31.5 16.9 23.2 19.4 40.4 17.7 21.8 27.1 34.6 20.3 32.3 22.0 28.0 31.3 26.7 18.1 16.8 27.7 19.3 20.4 22.9 25.1 21.7 26.2 30.6 17.6 28.3 14.0 50.7 28.4 43.2 14.1 18.7 48.5 20.5 44.9 11.0 3.8 4.6 2.7 7.2 8.2 8.5 8.7 8.9 7.9 7.5 6.1 9.6 8.3 0.6 6.1 7.1 3.9 6.9 5.3 6.5 7.2 8.6 8.2 6.1 7.8 7.4 7.8 7.7 6.5 7.0 7.2 25.6 32.1 33.1 19.6 29.7 22.9 33.9 28.4 14.2 20.7 18.8 17.1 48.0 20.0 37.4 23.9 10.4 27.7 23.6 10.2 21.5 32.3 14.6 28.8 34.5 31.3 16.8 19.5 31.4 34.9 30.0 26.4 16.3 30.0 22.1 36.8 21.4 18.6 19.7 21.9 28.8 11.5 22.4 15.3 22.6 12.1 23.6 19.9 33.8 10.3 35.2 12.8 24.7 20.1 24.0 38.2 8.9 16.6 31.3 32.2 8.8 30.1 49.5 28.7 19.7 35.3 31.4 40.3 56.1 17.1 25.4 24.9 25.3 33.5 18.7 41.4 BRCC3 "BRCC36, C6.1A, CXorf53" ENSG00000185515 "BRCA1/BRCA2-containing complex subunit 3" P46736 X 155071420-155123077 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Metalloprotease, Protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048737 Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA048737: AB_2680504" "unprognostic (1.16e-2)" "unprognostic (2.40e-2)" "unprognostic (5.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (2.88e-2)" "unprognostic (4.48e-2)" "unprognostic (6.47e-3)" "unprognostic (1.33e-1)" "unprognostic (9.68e-2)" "unprognostic (1.35e-3)" "unprognostic (3.72e-2)" "unprognostic (3.71e-3)" "unprognostic (7.14e-3)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "unprognostic (1.90e-1)" 9.9 12.9 6.8 12.1 6.6 15.6 15.8 9.2 7.7 12.8 6.8 22.3 19.3 9.2 18.5 18.4 11.6 8.4 11.2 6.6 7.0 17.8 13.8 9.8 15.4 5.9 7.1 8.1 11.4 14.7 5.2 14.0 6.7 14.6 23.3 12.9 18.5 10.9 17.8 11.1 16.9 10.6 5.4 11.0 15.6 2.3 7.4 13.4 15.2 17.6 15.5 12.6 6.3 6.6 95.6 45.1 24.4 19.6 20.9 17.7 37.9 35.9 25.8 24.1 52.3 44.0 40.1 84.1 62.8 22.1 36.1 36.3 54.4 33.6 38.0 45.4 42.1 17.7 76.1 41.4 15.8 62.8 25.5 17.3 16.9 35.1 28.5 23.1 30.1 32.2 27.4 24.9 24.6 33.6 25.8 28.8 22.3 101.9 41.9 36.2 43.3 42.0 36.8 36.5 38.0 17.3 25.6 43.6 27.3 31.5 25.2 33.7 31.5 20.4 32.1 27.6 53.8 30.0 56.1 114.5 28.2 61.5 25.3 36.8 18.8 34.0 20.0 22.9 23.4 17.6 19.3 18.2 21.2 16.7 14.8 16.6 10.5 28.4 24.1 13.3 25.4 16.9 6.8 6.6 9.2 7.7 6.6 7.0 5.9 7.1 6.7 5.4 7.4 6.6 12.0 32.1 23.3 16.6 14.0 5.5 7.0 13.8 6.8 13.0 15.0 14.0 27.2 10.0 28.5 7.3 14.6 26.7 17.6 25.5 19.6 22.9 0.6 13.8 13.7 10.6 9.6 17.1 31.9 19.8 26.6 11.3 12.8 15.9 26.6 13.7 8.6 8.6 17.4 8.4 35.2 22.6 16.2 9.5 7.0 1.3 5.9 14.5 5.4 15.9 22.3 12.9 20.6 26.7 29.2 14.7 16.8 12.0 21.1 10.3 16.3 18.0 25.1 14.5 19.7 12.6 22.9 1.2 1.3 26.2 6.5 13.5 14.9 18.3 27.3 8.3 BRIX1 "BRIX, BXDC2, FLJ11100" ENSG00000113460 "Biogenesis of ribosomes BRX1" Q8TDN6 5 34915677-34925996 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039614 Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Mitotic chromosome" "HPA039614: AB_10963698" "prognostic unfavorable (2.18e-4)" "unprognostic (2.60e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.10e-5)" "unprognostic (1.82e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (4.11e-8)" "unprognostic (3.37e-2)" "unprognostic (3.84e-3)" "prognostic favorable (6.34e-4)" "unprognostic (1.24e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.07e-9)" "unprognostic (1.95e-2)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "unprognostic (2.09e-2)" 18.6 17.1 13.3 17.6 13.8 37.1 24.7 15.2 18.7 15.1 12.8 15.6 12.9 17.4 17.8 17.7 16.1 12.2 14.7 13.2 14.1 15.1 18.5 13.0 26.4 13.7 13.6 18.5 13.7 18.2 9.5 25.7 13.8 15.7 17.1 11.6 12.9 14.5 10.4 14.6 12.8 16.1 13.9 14.3 13.1 13.9 13.5 20.7 15.8 12.2 25.8 30.1 12.3 15.2 66.1 57.0 64.2 87.1 26.0 37.8 121.6 74.9 52.7 100.0 63.5 74.5 81.0 138.8 38.7 45.5 113.5 52.1 108.5 79.8 117.3 75.1 101.3 93.9 125.7 71.9 67.4 150.8 63.8 44.4 49.8 93.3 85.9 31.0 48.5 72.9 158.4 43.8 66.2 63.6 108.3 163.9 101.0 75.2 86.8 94.6 112.5 60.5 59.3 70.7 75.1 68.8 157.6 109.7 76.1 50.0 66.4 92.7 28.4 78.7 87.5 58.1 151.0 39.3 87.7 177.6 66.3 171.3 100.3 15.0 21.4 10.0 34.5 21.0 50.1 63.7 43.2 44.3 27.8 49.9 53.3 46.6 1.2 43.7 30.6 37.5 43.5 44.6 13.3 13.8 15.2 18.7 13.2 14.1 13.7 13.6 13.8 13.9 13.5 15.2 35.5 28.9 30.7 8.5 40.0 108.7 114.3 110.2 55.2 20.8 27.3 41.3 23.2 25.8 63.0 23.9 12.5 127.1 37.0 13.5 49.0 52.5 24.8 29.9 45.1 40.6 21.0 45.2 11.9 42.7 100.6 44.4 19.4 31.6 20.2 30.0 20.0 11.9 42.7 21.9 13.4 19.0 63.1 10.7 20.1 8.4 39.4 18.4 32.0 4.7 31.1 22.3 21.6 10.6 13.6 44.7 13.1 29.0 21.4 70.9 9.9 37.9 45.8 37.2 6.6 54.3 55.7 59.9 77.6 46.0 95.8 126.1 37.1 31.7 31.9 85.1 BRPF1 BR140 ENSG00000156983 "Bromodomain and PHD finger containing 1" P55201 3 9731729-9748015 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 82.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003359 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA003359: AB_1078217" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (6.47e-2)" "unprognostic (9.10e-2)" "unprognostic (3.42e-1)" "unprognostic (2.33e-2)" "prognostic unfavorable (3.20e-5)" "unprognostic (3.00e-1)" "unprognostic (3.72e-1)" "unprognostic (3.26e-3)" "unprognostic (4.27e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (1.51e-3)" "unprognostic (4.86e-2)" "unprognostic (3.55e-1)" "unprognostic (6.87e-2)" "unprognostic (9.67e-3)" 8.0 7.1 4.7 6.9 6.9 23.5 7.7 9.9 7.4 8.2 3.8 8.3 4.8 9.5 4.4 8.6 8.8 5.5 7.3 6.7 3.8 6.2 5.5 7.9 8.9 4.7 4.2 9.3 7.3 7.7 6.7 6.5 4.3 7.5 4.0 4.0 9.1 5.0 9.5 10.9 8.3 5.4 3.1 10.5 7.5 14.4 5.2 11.9 9.0 6.8 7.6 7.9 7.8 5.5 9.9 17.2 12.5 8.2 8.9 8.6 82.4 12.6 7.5 14.3 10.2 12.1 8.3 18.6 6.0 11.6 13.5 8.2 15.3 12.0 9.0 20.1 17.9 21.4 33.8 9.8 11.4 30.6 20.0 8.5 9.8 19.8 13.1 7.2 10.8 17.5 25.2 15.9 8.3 24.3 19.8 25.7 20.6 6.7 15.9 28.7 10.6 12.3 6.7 14.5 8.9 15.2 12.7 9.0 10.1 8.2 9.8 31.4 14.1 15.9 13.6 14.5 24.0 13.4 18.1 31.5 13.1 25.9 15.1 1.0 0.9 1.4 1.3 0.8 2.0 0.6 0.9 1.2 0.8 0.5 1.1 1.3 0.8 4.2 0.7 1.9 0.7 0.8 4.7 6.9 9.9 7.4 6.7 3.8 4.7 4.2 4.3 3.1 5.2 5.5 7.9 16.0 10.0 2.6 6.8 14.1 5.1 3.9 8.0 4.6 9.2 7.0 3.7 2.8 6.2 7.3 6.2 4.2 13.0 9.4 0.0 4.1 3.9 4.2 6.9 9.7 10.2 9.7 3.4 5.5 5.5 5.8 7.7 7.0 8.8 7.3 11.0 3.5 6.4 8.4 2.4 5.0 2.0 5.6 9.2 1.2 6.5 6.9 1.8 2.8 6.3 5.2 5.2 4.0 2.9 6.1 3.1 6.0 7.9 5.1 4.9 2.1 4.3 5.1 6.6 11.3 7.7 16.6 13.9 9.9 18.5 3.7 10.8 5.6 6.1 6.8 BTF3L4 MGC23908 ENSG00000134717 "Basic transcription factor 3 like 4" Q96K17 1 52056199-52090716 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067026 Approved Approved Nucleoplasm,Cytosol NA NA 59000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA067026: AB_2685765" "unprognostic (6.12e-2)" "unprognostic (6.33e-2)" "unprognostic (5.09e-2)" "unprognostic (8.83e-3)" "unprognostic (1.42e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (6.73e-8)" "unprognostic (8.85e-2)" "unprognostic (5.59e-2)" "unprognostic (1.71e-3)" "unprognostic (2.61e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (4.43e-6)" "unprognostic (1.62e-1)" "unprognostic (2.56e-1)" "unprognostic (1.68e-1)" "unprognostic (8.56e-2)" 44.6 51.9 28.4 30.3 29.3 61.0 43.6 28.8 36.1 31.4 28.3 25.1 14.5 36.4 30.7 36.0 36.5 23.9 40.1 28.8 33.0 35.0 40.9 26.3 36.6 31.0 31.2 52.9 38.3 42.1 31.0 37.4 31.6 29.2 23.6 31.4 29.9 24.5 70.1 35.9 18.6 34.8 30.3 28.1 27.6 34.0 31.8 49.2 43.1 59.0 40.8 42.3 29.9 39.7 99.8 23.7 113.5 59.6 60.4 76.4 117.3 96.1 96.3 108.0 115.2 43.8 50.8 92.3 93.9 68.3 127.1 56.6 111.1 75.0 137.0 64.4 77.7 105.8 41.0 65.5 163.8 118.2 70.0 79.2 101.0 100.2 140.1 89.1 86.9 75.1 81.5 57.0 98.0 42.1 82.6 69.9 202.7 76.7 51.2 53.6 132.1 109.8 105.3 78.6 89.1 100.6 112.5 102.8 141.7 124.8 92.8 124.8 64.0 60.5 65.4 78.4 114.8 98.9 176.3 89.4 52.2 90.0 77.9 70.3 74.2 70.9 29.7 78.9 40.2 49.9 42.8 31.0 72.9 49.7 49.1 38.2 31.6 49.7 70.9 34.3 62.6 64.3 28.4 29.3 28.8 36.1 28.8 33.0 31.0 31.2 31.6 30.3 31.8 39.7 60.4 35.3 22.3 17.0 76.0 107.7 91.7 153.6 65.4 43.6 81.2 75.6 44.7 52.9 82.2 69.9 33.3 111.1 45.9 18.7 168.3 106.0 115.3 82.9 83.6 55.1 52.2 114.9 30.8 80.1 137.6 77.2 44.4 73.3 22.8 128.2 56.0 81.0 129.3 38.7 32.9 33.8 120.1 127.8 92.9 25.4 72.4 87.4 78.2 27.2 86.5 62.0 49.4 29.7 39.5 72.7 26.3 55.7 58.7 135.9 23.4 162.9 75.7 33.2 59.2 73.7 106.3 97.1 31.1 108.5 160.3 145.8 56.0 114.9 34.8 106.7 BUD31 "Cwc14, EDG-2, EDG2, fSAP17, G10, YCR063W" ENSG00000106245 "BUD31 homolog" P41223 7 99408641-99419616 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028943 Approved Approved Nucleoplasm,Microtubules,Centrosome NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Microtubules, Centrosome" "HPA028943: AB_10602396" "unprognostic (1.68e-1)" "unprognostic (2.73e-2)" "unprognostic (2.89e-2)" "unprognostic (2.63e-2)" "unprognostic (5.29e-2)" "unprognostic (2.38e-2)" "unprognostic (2.02e-3)" "unprognostic (2.16e-2)" "unprognostic (4.02e-2)" "unprognostic (1.46e-2)" "unprognostic (8.71e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (9.66e-4)" "unprognostic (1.42e-1)" "unprognostic (4.10e-2)" "unprognostic (1.55e-1)" "unprognostic (1.71e-1)" 48.2 47.1 51.3 32.6 51.0 91.7 45.9 54.5 59.7 37.8 52.3 46.4 32.0 38.1 35.4 49.6 39.9 32.2 39.6 51.9 51.8 65.5 42.9 43.4 45.5 51.4 51.3 39.0 33.9 41.1 54.0 33.9 51.6 42.3 25.7 14.8 37.9 30.8 31.6 40.8 35.2 29.2 51.5 40.9 44.0 68.4 55.0 41.1 41.2 25.1 35.8 40.3 40.7 53.2 111.2 123.9 67.5 153.9 67.3 75.0 67.0 103.7 96.7 113.4 124.1 148.5 104.5 83.7 122.7 98.3 123.8 65.5 76.0 92.9 93.8 102.3 106.9 61.1 83.1 98.2 139.4 106.0 78.2 73.8 112.1 104.1 195.1 66.4 89.8 87.6 151.7 182.3 106.2 283.9 143.3 281.2 152.2 114.6 156.8 73.2 69.5 145.7 100.7 85.6 120.3 145.8 101.8 114.9 216.8 43.8 72.2 129.0 74.8 108.1 138.5 216.8 163.6 115.0 207.2 220.9 94.9 153.6 199.4 390.7 206.8 516.9 175.8 232.0 164.7 226.1 165.5 171.2 175.9 223.9 140.0 145.7 451.2 203.7 252.6 171.2 215.7 360.5 51.3 51.0 54.5 59.7 51.9 51.8 51.4 51.3 51.6 51.5 55.0 53.2 103.2 83.3 81.2 3.6 88.1 192.7 142.3 192.7 103.6 32.8 94.8 134.1 12.8 68.6 110.5 92.0 10.4 169.9 118.5 157.7 238.7 169.9 173.1 137.3 91.7 98.1 146.8 85.2 5.7 187.1 163.0 97.9 65.2 111.9 91.2 79.6 86.0 84.3 151.5 16.8 5.6 187.2 111.9 89.2 125.1 121.3 82.0 90.8 136.9 5.6 148.5 103.5 116.4 5.0 6.8 248.1 153.8 74.1 68.4 153.9 155.4 242.3 171.2 40.1 59.2 77.4 144.3 298.2 135.7 99.1 183.8 182.4 112.0 86.9 132.3 174.8 C17orf49 "BAP18, HEPIS, MGC49942" ENSG00000258315 "Chromosome 17 open reading frame 49" Q8IXM2 17 7014495-7017525 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 62.0;Smooth muscle cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA022961, HPA024457" Supported Uncertain Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA022961: AB_1845592, HPA024457: AB_1845593" "unprognostic (1.48e-2)" "unprognostic (1.67e-3)" "unprognostic (9.09e-2)" "unprognostic (5.15e-2)" "unprognostic (4.54e-1)" "unprognostic (3.27e-2)" "unprognostic (2.38e-1)" "unprognostic (7.62e-2)" "unprognostic (2.27e-2)" "unprognostic (4.06e-2)" "unprognostic (2.25e-2)" "unprognostic (1.49e-2)" "unprognostic (1.06e-9)" "unprognostic (5.68e-2)" "unprognostic (1.74e-1)" "unprognostic (1.41e-2)" "unprognostic (4.62e-2)" 62.3 42.6 54.9 61.5 54.6 122.1 55.5 55.6 60.4 42.1 49.3 37.8 34.9 36.0 53.1 52.8 49.3 38.2 53.1 53.7 55.4 47.2 47.1 55.3 97.5 54.6 54.0 35.6 50.8 37.7 40.1 36.9 54.1 35.3 42.3 39.2 42.2 26.8 69.6 63.1 37.0 34.0 54.6 73.0 35.5 28.2 57.2 97.6 52.9 55.1 105.4 53.9 39.5 55.9 68.2 88.3 136.8 106.6 95.4 134.5 47.0 36.1 58.7 70.8 57.5 43.6 54.5 64.6 97.1 86.8 23.0 55.1 34.5 69.8 53.7 227.6 91.6 58.4 27.9 85.3 71.6 37.7 74.8 85.4 92.4 52.9 106.0 50.7 112.0 51.6 21.9 179.3 87.5 77.7 62.3 125.1 45.9 77.1 51.2 38.3 40.0 95.1 80.9 44.6 37.2 105.3 63.4 32.3 67.5 49.1 41.0 47.9 61.7 40.8 50.3 69.7 93.5 63.8 39.5 22.5 63.6 55.6 59.9 259.3 159.7 157.7 190.8 225.8 122.3 238.7 195.9 193.8 251.3 221.0 128.9 143.0 148.1 391.4 177.4 346.7 215.3 193.1 54.9 54.6 55.6 60.4 53.7 55.4 54.6 54.0 54.1 54.6 57.2 55.9 9.6 3.2 10.3 0.0 18.2 10.5 5.9 8.2 13.1 1.2 8.9 11.2 1.1 2.8 7.2 1.8 0.0 10.9 18.1 8.2 17.6 17.7 0.2 2.3 4.1 12.3 30.6 8.6 0.0 23.1 16.5 6.0 2.6 4.2 18.9 3.1 9.3 2.1 11.1 0.0 0.0 12.5 14.2 7.8 32.3 1.4 4.1 12.0 24.9 0.0 62.0 2.1 16.5 0.0 0.0 24.2 14.3 1.5 14.1 6.6 8.8 6.0 4.1 3.5 6.6 6.1 41.9 5.4 18.5 11.9 11.8 10.4 17.6 3.3 14.0 6.2 C5orf34 FLJ32363 ENSG00000172244 "Chromosome 5 open reading frame 34" Q96MH7 5 43486709-43515148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 19.7;Spermatocytes: 18.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045386 Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "HPA045386: AB_10965552" "unprognostic (2.67e-2)" "unprognostic (1.25e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (2.65e-6)" "unprognostic (1.08e-1)" "unprognostic (1.07e-2)" "unprognostic (1.66e-4)" "unprognostic (7.79e-3)" "unprognostic (6.51e-3)" "unprognostic (4.00e-2)" "unprognostic (4.61e-2)" "unprognostic (2.09e-1)" "unprognostic (9.97e-6)" "unprognostic (9.87e-2)" "unprognostic (1.45e-1)" "unprognostic (1.39e-3)" "unprognostic (5.99e-2)" 0.9 0.4 0.6 1.3 0.7 1.1 1.6 0.3 0.8 1.2 0.3 1.0 0.6 0.9 0.4 1.0 0.8 0.6 0.5 0.8 0.6 0.8 0.4 0.7 2.8 0.8 0.7 0.8 0.3 0.4 0.3 1.1 0.8 2.4 1.3 0.5 1.0 1.2 0.4 1.3 0.8 1.2 0.8 1.0 0.7 4.1 0.5 3.6 1.2 0.4 2.4 1.4 1.1 0.8 5.6 6.5 9.3 11.1 1.4 3.1 10.5 8.3 7.6 13.3 10.5 4.0 5.7 14.7 8.5 2.7 18.1 5.4 11.3 3.9 14.7 6.9 13.4 3.0 24.0 3.5 0.6 8.1 1.7 2.4 1.3 13.5 7.3 2.1 6.4 7.9 9.5 3.9 10.6 4.3 4.4 11.3 6.6 2.4 7.3 8.2 18.5 9.2 3.6 2.6 6.5 8.0 14.1 6.8 5.8 5.6 11.4 8.5 4.1 10.5 12.9 11.0 8.8 4.1 6.0 8.9 6.0 10.3 11.4 0.0 0.0 0.0 0.5 0.2 0.8 0.7 0.5 0.5 0.3 0.4 0.7 1.4 0.3 0.9 0.1 2.5 0.2 0.3 0.6 0.7 0.3 0.8 0.8 0.6 0.8 0.7 0.8 0.8 0.5 0.8 1.7 3.2 0.5 0.7 2.6 1.7 1.8 1.4 1.2 0.3 1.2 1.7 0.7 0.0 0.5 1.8 0.0 3.7 3.1 0.2 1.9 1.0 1.3 0.9 1.1 1.3 0.0 7.0 8.6 1.5 4.4 1.5 2.0 1.4 5.1 5.0 2.5 0.0 1.7 0.0 3.0 0.4 2.0 1.2 1.4 1.3 1.2 1.2 1.8 1.0 2.7 0.1 0.0 0.5 2.4 0.8 0.3 0.7 2.0 1.6 0.3 0.5 0.5 0.6 19.7 0.6 3.6 18.9 6.9 2.3 2.0 0.4 1.6 1.9 1.6 2.2 C8orf76 FLJ14825 ENSG00000189376 "Chromosome 8 open reading frame 76" Q96K31 8 123219967-123241377 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 136.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 164.9" HPA023708 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA023708: AB_1845785" "prognostic unfavorable (9.95e-4)" "unprognostic (1.61e-1)" "unprognostic (9.71e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (1.27e-1)" "unprognostic (6.78e-2)" "unprognostic (4.47e-3)" "unprognostic (1.48e-2)" "unprognostic (2.49e-2)" "unprognostic (1.43e-1)" "unprognostic (3.50e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (5.95e-11)" "unprognostic (1.54e-2)" "unprognostic (1.94e-1)" "unprognostic (3.26e-1)" "unprognostic (2.71e-2)" 10.5 14.1 12.0 9.5 12.8 12.6 10.8 13.3 15.0 9.3 13.3 10.8 9.4 7.7 11.4 15.4 8.9 8.7 13.0 12.0 12.6 9.2 18.4 9.4 14.1 12.3 12.5 8.3 10.8 7.7 17.3 12.2 12.4 10.5 11.8 11.0 12.5 8.1 15.2 8.4 11.1 7.8 12.7 14.3 10.0 7.3 12.6 13.9 9.8 7.9 13.9 10.5 10.3 13.4 24.7 22.4 20.3 14.3 19.5 17.8 13.9 22.7 22.0 26.0 26.1 20.5 17.5 16.8 24.4 21.9 19.4 18.4 22.9 12.4 29.3 27.0 31.9 19.7 10.1 28.0 35.0 10.5 15.6 13.1 23.3 23.3 19.4 15.2 23.4 25.9 28.6 12.8 21.9 72.3 30.7 23.1 16.6 59.4 37.6 16.1 10.4 19.3 22.4 20.1 26.7 24.8 22.7 164.9 25.0 20.6 20.2 24.7 12.9 14.8 28.3 16.1 19.0 16.8 19.8 18.2 15.9 23.7 16.3 19.9 18.3 28.3 13.6 21.4 14.4 11.7 14.8 17.6 19.2 14.8 14.0 14.1 10.9 15.0 18.1 16.8 21.3 13.2 12.0 12.8 13.3 15.0 12.0 12.6 12.3 12.5 12.4 12.7 12.6 13.4 12.4 12.8 2.0 7.2 17.7 13.5 17.8 29.0 17.1 8.2 13.8 13.8 5.9 7.2 25.4 1.8 10.4 27.4 23.4 21.3 5.9 16.4 5.1 10.7 15.4 11.7 24.7 8.6 6.8 11.8 31.5 15.1 8.2 11.5 22.2 10.8 8.9 11.1 22.6 136.3 8.2 12.5 32.6 14.5 17.7 4.0 12.8 16.3 14.2 3.7 21.7 12.9 20.6 3.5 8.8 14.8 13.8 7.5 19.1 21.6 19.4 11.2 48.3 7.7 19.7 11.5 28.7 14.4 17.1 12.6 11.5 40.2 18.1 8.8 15.7 39.9 CCAR1 "CARP-1, CARP1, FLJ10590" ENSG00000060339 "Cell division cycle and apoptosis regulator 1" Q8IX12 10 68721012-68792377 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007856, HPA048513" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Golgi apparatus" "HPA007856: AB_1078415, HPA048513: AB_2680424" "unprognostic (1.71e-1)" "unprognostic (1.22e-1)" "unprognostic (2.34e-2)" "unprognostic (1.86e-1)" "unprognostic (5.15e-3)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.41e-5)" "unprognostic (1.10e-1)" "unprognostic (3.25e-2)" "prognostic favorable (4.05e-5)" "unprognostic (2.89e-2)" "unprognostic (3.21e-3)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.67e-1)" "unprognostic (2.36e-1)" "unprognostic (2.24e-1)" "unprognostic (1.41e-2)" 17.4 21.4 14.4 20.2 16.0 23.4 17.2 21.1 25.4 15.9 15.2 17.9 16.8 16.7 16.1 20.1 14.5 16.5 15.6 13.6 17.0 18.4 19.1 15.9 30.3 16.9 14.9 19.9 20.4 15.9 14.5 21.7 16.4 17.3 22.2 20.9 18.5 13.5 20.6 23.9 19.4 16.0 13.2 21.5 17.8 14.3 16.8 29.8 18.2 17.9 28.7 21.7 17.0 19.2 64.0 64.8 73.9 49.7 31.4 30.3 57.7 56.0 47.4 59.3 40.0 87.2 50.8 74.7 29.9 39.1 29.8 49.3 78.4 44.3 64.8 51.5 48.2 60.1 46.1 54.5 35.7 96.2 67.5 30.5 54.2 50.1 61.7 36.7 48.5 37.5 83.5 46.8 58.8 46.5 64.2 60.7 74.1 49.7 58.4 74.2 44.1 44.7 52.5 48.6 42.7 36.9 55.1 89.1 57.1 57.6 60.6 58.9 48.1 36.8 46.3 40.1 61.4 32.2 45.5 78.5 30.8 63.8 35.6 6.1 14.6 14.3 16.3 13.0 14.6 14.2 11.3 15.8 21.0 17.3 13.5 14.3 3.3 10.6 15.5 13.1 18.4 11.3 14.4 16.0 21.1 25.4 13.6 17.0 16.9 14.9 16.4 13.2 16.8 19.2 50.5 35.3 85.5 61.4 69.2 37.0 49.6 54.7 66.0 51.0 36.1 40.0 65.5 41.5 49.0 46.0 58.4 73.1 62.9 44.1 23.5 68.0 28.8 55.2 68.5 54.0 46.1 61.2 49.7 78.1 83.8 49.2 45.3 62.2 67.2 76.8 39.3 40.4 49.2 55.5 51.2 55.1 30.5 47.4 36.3 14.5 53.7 49.8 21.4 41.2 65.4 36.5 66.9 47.7 66.1 77.7 34.2 50.4 61.0 45.3 36.0 18.3 49.1 68.7 65.7 53.2 62.3 128.7 77.2 50.4 37.4 109.5 61.3 83.2 67.2 49.4 CCDC47 GK001 ENSG00000108588 "Coiled-coil domain containing 47" Q96A33 17 63745255-63776351 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029674, HPA072573, HPA075958" Approved Enhanced "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA029674: AB_10602703, HPA072573: AB_2686535, HPA075958: " "unprognostic (6.33e-2)" "unprognostic (3.26e-2)" "prognostic favorable (2.17e-4)" "unprognostic (1.38e-1)" "unprognostic (3.54e-1)" "unprognostic (1.47e-2)" "unprognostic (1.53e-2)" "unprognostic (9.08e-2)" "unprognostic (1.57e-1)" "unprognostic (3.68e-1)" "unprognostic (2.73e-1)" "unprognostic (1.26e-1)" "unprognostic (8.35e-2)" "unprognostic (1.88e-1)" "unprognostic (6.43e-2)" "unprognostic (7.46e-2)" "unprognostic (1.16e-1)" 57.9 67.3 24.3 42.5 33.6 29.0 57.1 28.8 39.2 47.7 46.9 83.4 87.1 39.1 53.7 52.6 43.9 48.2 65.5 29.3 27.9 72.0 102.2 52.7 33.5 28.8 27.4 35.3 59.8 84.6 21.9 54.8 29.9 60.2 80.6 46.9 62.4 52.0 115.3 52.2 78.2 42.1 30.1 35.6 78.5 32.1 26.0 29.9 62.0 83.7 40.5 58.5 29.3 34.3 143.3 133.8 81.4 71.9 112.4 74.0 158.0 141.9 92.6 96.1 112.4 118.7 127.0 112.9 74.3 100.9 110.8 114.3 99.3 88.1 168.9 39.4 101.2 160.9 106.4 117.3 107.6 129.9 81.3 78.5 121.3 132.4 113.2 67.9 81.3 55.3 183.5 95.5 79.4 116.1 100.5 48.1 70.8 179.4 134.0 92.2 157.9 154.6 115.3 161.1 74.2 101.5 95.2 242.8 120.3 103.0 159.8 70.4 104.0 177.6 112.9 130.6 166.0 93.9 119.9 112.8 103.9 81.4 147.3 53.2 59.7 75.6 40.7 61.5 47.9 38.4 39.8 37.9 82.5 31.7 41.1 36.2 47.6 43.4 65.9 54.7 49.0 52.0 24.3 33.6 28.8 39.2 29.3 27.9 28.8 27.4 29.9 30.1 26.0 34.3 96.9 144.2 122.2 16.3 46.6 100.8 108.5 95.9 98.4 40.9 65.9 53.6 129.0 72.9 128.3 60.7 14.6 111.1 59.0 99.8 9.8 115.3 17.9 80.3 73.9 83.9 52.2 76.6 26.2 105.1 98.3 85.3 65.7 126.0 45.5 31.2 68.2 96.3 57.5 57.2 25.9 95.1 83.4 56.9 58.3 11.5 47.8 60.7 39.2 13.1 52.9 55.3 25.7 22.6 25.5 92.0 62.6 56.1 56.0 89.6 87.5 32.6 83.0 27.9 72.3 117.2 92.1 82.0 44.7 90.1 90.8 144.1 42.7 53.0 110.5 83.3 CCDC58 FLJ33273 ENSG00000160124 "Coiled-coil domain containing 58" Q4VC31 3 122359591-122383231 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 114.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051965 Approved Approved Nucleoli,Mitochondria No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoli "HPA051965: AB_2681676" "unprognostic (1.51e-1)" "unprognostic (1.23e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (5.64e-2)" "unprognostic (6.98e-3)" "prognostic unfavorable (2.94e-5)" "unprognostic (2.72e-2)" "unprognostic (1.03e-2)" "unprognostic (4.98e-3)" "unprognostic (5.26e-3)" "unprognostic (1.84e-2)" "unprognostic (7.11e-3)" "unprognostic (1.03e-3)" "unprognostic (2.58e-1)" "unprognostic (1.86e-1)" "prognostic favorable (7.29e-4)" 14.7 21.0 16.9 15.7 17.8 18.0 19.0 18.2 28.2 10.7 18.4 28.5 22.5 11.7 24.6 23.2 10.6 13.4 27.3 17.1 17.6 46.8 49.8 9.0 23.3 17.8 18.1 13.1 13.8 14.9 7.8 14.4 18.2 11.1 29.1 17.1 11.3 10.6 78.8 15.0 18.6 11.4 17.4 12.1 16.4 9.4 18.1 16.2 18.3 47.2 21.5 22.6 12.5 18.3 135.1 41.9 78.2 50.2 28.5 39.8 100.6 50.5 54.3 119.4 116.4 118.4 66.4 98.0 84.6 38.6 92.7 91.9 127.9 86.3 142.5 34.1 45.3 115.9 28.5 145.6 47.5 174.5 39.5 33.0 43.9 73.5 79.8 50.7 55.9 85.8 133.6 41.6 63.7 67.2 111.7 123.6 150.0 147.2 78.1 72.8 92.9 120.1 83.7 70.3 78.8 38.4 58.5 61.5 150.5 65.3 61.2 112.8 32.6 66.4 86.1 28.6 102.3 32.9 47.5 217.4 75.7 83.3 60.0 0.9 7.7 2.7 15.2 16.7 18.0 20.9 19.9 20.1 16.5 19.2 23.0 22.2 1.4 19.2 14.2 29.2 17.2 6.7 16.9 17.8 18.2 28.2 17.1 17.6 17.8 18.1 18.2 17.4 18.1 18.3 5.7 3.2 17.0 8.1 18.1 15.3 19.1 21.4 21.1 10.5 14.1 10.4 32.0 20.0 22.2 12.9 10.4 21.8 8.4 19.6 54.8 31.4 0.5 24.7 20.5 13.7 5.4 14.1 11.3 30.0 44.7 12.8 16.8 26.2 21.5 14.4 10.8 50.5 17.8 0.0 13.2 27.7 16.2 8.7 7.6 1.5 12.8 8.9 8.8 2.8 19.8 9.7 16.5 11.6 11.8 31.9 14.7 8.2 12.5 30.7 23.9 114.0 22.5 9.6 13.1 15.1 41.8 23.1 31.0 30.8 18.5 15.2 10.9 11.8 35.1 23.0 CCT4 Cctd ENSG00000115484 "Chaperonin containing TCP1 subunit 4" P50991 2 61868085-61888671 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029349 Supported Supported Nucleoplasm,Cytosol NA NA 1700000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "HPA029349: AB_10600800" "prognostic unfavorable (2.03e-4)" "unprognostic (2.80e-2)" "unprognostic (6.46e-2)" "unprognostic (1.74e-3)" "unprognostic (5.03e-2)" "unprognostic (1.40e-2)" "prognostic unfavorable (9.37e-12)" "unprognostic (1.28e-3)" "unprognostic (2.48e-1)" "unprognostic (1.56e-1)" "unprognostic (4.88e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-2)" "unprognostic (5.18e-2)" "unprognostic (2.00e-1)" "unprognostic (3.96e-1)" "unprognostic (2.14e-2)" 66.4 67.0 60.4 59.9 62.6 64.9 90.2 67.1 114.9 68.4 66.7 65.1 45.8 68.7 50.8 75.6 74.4 43.1 67.0 62.3 65.7 73.5 63.7 48.7 81.4 63.9 62.6 109.3 95.3 62.8 45.9 65.8 66.1 57.8 58.9 56.8 53.7 57.5 96.7 66.4 48.5 72.0 70.4 55.3 64.5 77.6 66.0 83.3 65.3 74.0 92.0 68.4 61.2 80.0 274.5 313.6 203.1 190.1 166.2 251.5 342.5 244.6 174.3 345.6 230.4 550.5 193.2 437.9 239.7 176.5 354.6 192.4 405.8 313.9 362.3 216.0 398.9 280.4 149.4 347.7 149.3 347.8 179.1 215.0 214.4 278.8 287.2 259.5 293.3 220.0 406.5 137.2 297.5 246.4 299.6 451.2 365.3 364.2 276.0 336.9 319.2 297.4 237.5 186.2 177.6 148.8 177.2 221.9 324.5 235.7 161.9 245.6 185.2 190.6 275.5 143.3 400.1 205.3 297.3 739.8 188.9 391.7 255.7 58.2 60.7 25.0 83.2 88.9 106.9 93.6 87.1 100.8 100.4 88.6 112.9 112.2 8.4 107.5 103.3 64.3 100.7 125.2 60.4 62.6 67.1 114.9 62.3 65.7 63.9 62.6 66.1 70.4 66.0 80.0 111.8 73.7 54.3 20.9 125.4 152.6 350.8 206.6 136.1 52.9 131.3 136.4 47.7 82.9 116.7 73.5 14.6 256.5 106.5 52.8 135.0 156.0 250.0 111.9 117.2 118.0 140.6 156.9 28.0 130.6 284.9 114.9 67.8 92.8 95.8 148.2 95.3 79.4 163.5 32.0 31.3 105.9 175.0 105.0 112.4 72.1 88.3 110.2 94.3 30.0 125.8 64.9 71.1 26.7 40.8 143.9 61.4 97.8 111.9 200.3 67.9 165.2 143.1 63.3 92.1 117.2 297.8 338.8 153.2 151.2 151.3 180.6 146.6 173.7 138.2 203.8 CCT5 KIAA0098 ENSG00000150753 "Chaperonin containing TCP1 subunit 5" P48643 5 10249929-10266389 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002238, HPA005958, CAB006271" Enhanced NA NA 1400000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "CAB006271: AB_425898, HPA002238: AB_1078427, HPA005958: AB_1846209" "unprognostic (7.02e-3)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" "unprognostic (1.79e-2)" "unprognostic (3.46e-1)" "unprognostic (2.10e-3)" "prognostic unfavorable (6.57e-11)" "unprognostic (6.40e-3)" "unprognostic (2.04e-1)" "unprognostic (1.91e-3)" "unprognostic (1.13e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (8.23e-6)" "unprognostic (1.02e-1)" "unprognostic (1.94e-1)" "unprognostic (3.84e-1)" "unprognostic (1.82e-2)" 85.3 79.5 68.6 95.3 70.4 82.0 74.7 73.2 112.4 58.2 79.2 85.7 67.5 66.8 53.3 100.8 77.4 48.1 74.8 72.7 82.4 76.0 74.1 58.7 96.3 71.5 74.7 50.8 58.4 175.6 46.1 85.8 78.7 52.3 97.2 48.9 60.3 52.9 128.2 60.5 62.2 89.5 74.5 62.3 62.6 104.3 76.0 106.6 63.2 90.8 118.4 105.8 63.7 83.8 350.5 489.8 405.1 463.7 250.9 188.5 568.4 454.1 288.6 704.0 492.6 657.8 372.2 537.6 490.4 326.4 615.9 332.8 770.4 492.7 774.2 504.5 527.9 440.2 1063.7 510.7 293.8 667.6 303.7 221.3 300.3 556.8 368.9 191.4 422.7 343.6 597.5 188.2 453.3 494.0 481.4 659.7 432.6 348.3 579.4 437.9 304.4 275.8 447.3 359.1 304.8 335.3 953.5 424.6 335.6 316.9 327.2 490.9 285.2 576.4 517.7 214.1 687.9 192.2 322.7 570.1 323.7 955.4 470.8 125.6 181.5 139.3 117.5 248.8 155.7 151.6 131.3 130.7 188.9 125.6 121.8 123.7 101.4 147.3 286.1 69.5 150.3 255.3 68.6 70.4 73.2 112.4 72.7 82.4 71.5 74.7 78.7 74.5 76.0 83.8 81.7 67.3 41.3 12.1 71.5 88.2 172.1 206.6 60.3 46.7 50.7 54.6 23.6 51.5 116.7 49.7 18.8 214.2 60.7 81.4 49.0 217.4 235.1 127.0 107.5 92.8 70.9 98.2 16.8 162.8 271.8 81.8 62.7 101.1 48.8 100.7 40.0 52.5 175.7 35.3 19.3 89.9 116.0 69.2 64.7 93.1 83.0 84.0 40.9 13.1 92.1 56.6 72.1 19.1 22.9 199.0 81.8 75.6 59.6 128.5 61.0 99.2 131.7 60.8 72.3 81.0 272.5 282.3 184.4 93.1 74.6 155.4 66.5 170.2 126.9 126.1 CCT8 "C21orf112, Cctq, PRED71" ENSG00000156261 "Chaperonin containing TCP1 subunit 8" P50990 21 29055805-29073797 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018520, HPA021051, HPA029426" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" No No 1100000 "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA018520: AB_1846204, HPA021051: AB_1846205, HPA029426: AB_10601796" "unprognostic (3.41e-3)" "unprognostic (2.75e-2)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (1.25e-1)" "unprognostic (4.25e-3)" "prognostic unfavorable (1.56e-5)" "unprognostic (8.78e-2)" "unprognostic (1.37e-1)" "unprognostic (3.09e-1)" "unprognostic (1.02e-2)" "unprognostic (2.91e-1)" "unprognostic (3.01e-2)" "unprognostic (8.26e-2)" "unprognostic (3.50e-2)" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" 72.7 125.0 62.5 99.1 67.0 99.5 100.4 70.3 84.0 78.5 78.0 87.9 77.9 74.8 88.2 83.7 80.9 64.3 116.3 66.9 74.7 102.7 92.7 70.1 140.8 64.5 65.3 88.0 95.3 100.0 40.6 107.0 69.0 77.1 102.1 71.3 70.7 72.5 121.1 75.0 78.6 85.5 66.7 88.9 68.8 79.1 68.7 141.2 78.5 145.2 154.3 122.3 50.3 66.1 437.4 243.1 319.4 233.3 220.4 302.3 350.9 340.5 219.1 386.2 317.5 548.6 269.0 858.8 229.1 237.1 466.8 174.4 632.2 391.7 441.1 364.0 348.1 1185.2 289.8 384.3 227.0 609.0 335.6 229.0 244.9 448.6 372.6 278.6 368.1 379.7 935.8 519.0 404.1 270.9 456.6 359.4 572.6 433.6 310.6 411.7 596.5 547.4 409.1 283.2 316.7 231.6 334.1 356.6 364.7 347.5 319.9 526.7 267.4 221.3 613.7 216.7 439.7 329.2 651.8 695.1 256.3 704.5 339.0 79.9 110.1 54.4 56.9 120.9 79.6 79.8 76.3 73.4 133.3 61.8 85.5 82.1 11.5 87.7 132.2 83.5 92.7 127.4 62.5 67.0 70.3 84.0 66.9 74.7 64.5 65.3 69.0 66.7 68.7 66.1 66.9 64.1 61.7 15.0 120.1 143.1 197.6 278.6 70.0 85.6 88.4 76.5 75.7 90.1 150.0 75.4 18.8 268.9 122.1 67.3 144.8 194.1 17.0 106.6 92.8 94.8 97.0 150.2 26.7 138.0 275.8 93.4 52.0 73.7 112.8 135.6 55.3 53.4 170.5 77.4 31.3 106.2 201.4 115.6 122.4 20.5 84.2 109.9 115.6 26.2 226.6 96.1 97.9 13.6 21.4 131.2 92.1 92.9 130.7 185.9 107.4 189.7 147.7 84.6 105.2 88.7 214.7 170.1 176.8 90.2 131.4 285.3 105.1 254.5 161.1 170.6 CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34, ubiqiutin conjugating enzyme" P49427 19 531760-542092 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 249.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311, HPA074334" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370, HPA074334: " "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" 35.1 36.7 52.0 13.3 51.2 34.5 34.2 51.5 63.0 36.9 47.5 62.5 17.8 33.5 14.1 40.5 33.6 10.1 80.0 52.7 48.7 32.1 88.0 32.1 12.5 51.0 50.7 35.6 58.5 18.7 43.4 29.2 50.8 36.9 11.5 28.2 34.2 19.3 105.0 51.8 27.6 18.5 48.2 31.0 38.6 100.2 52.7 16.4 26.7 63.2 9.7 43.7 34.2 52.7 54.8 54.6 66.4 54.7 29.2 28.4 68.5 47.8 36.1 50.2 51.9 86.1 32.8 29.5 49.3 34.1 30.1 36.9 52.1 40.2 25.0 49.2 146.0 27.8 35.5 94.5 73.6 39.0 32.4 36.4 58.9 42.2 43.6 38.8 60.6 41.2 120.3 57.5 33.8 80.7 53.3 53.6 85.3 39.4 51.7 49.1 35.1 51.2 38.0 32.4 87.2 65.9 41.5 42.1 85.2 53.2 34.0 57.4 50.5 36.5 43.7 86.2 65.2 57.7 47.3 40.1 50.0 55.6 38.8 3.2 2.5 4.7 1.6 2.7 1.1 2.3 2.1 2.9 2.0 1.0 1.6 1.6 8.2 1.2 3.5 1.6 2.5 1.0 52.0 51.2 51.5 63.0 52.7 48.7 51.0 50.7 50.8 48.2 52.7 52.7 39.4 0.0 5.4 21.9 11.4 46.8 17.5 5.4 16.5 35.5 43.4 47.1 27.7 27.1 3.5 14.7 25.0 44.3 30.9 47.4 13.7 24.9 63.9 29.6 28.3 27.7 13.2 77.7 8.3 20.5 55.4 21.4 16.8 42.3 0.0 28.1 15.7 41.1 27.9 16.8 6.3 34.0 14.2 14.5 38.6 249.4 18.0 20.6 19.6 2.8 15.1 68.9 20.6 6.6 12.9 45.0 27.0 15.1 25.0 34.8 25.9 18.9 5.5 44.3 13.1 22.6 34.9 22.4 54.6 15.2 54.7 63.1 22.0 27.1 23.7 27.9 CDC42 "CDC42Hs, G25K" ENSG00000070831 "Cell division cycle 42" P60953 1 22025511-22101360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004360, HPA069590" Approved Supported "Microtubules,Cytokinetic bridge" Yes No 2700000 "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Microtubules, Cytokinetic bridge" "CAB004360: AB_627233, HPA069590: AB_2732138" "unprognostic (9.40e-2)" "unprognostic (1.37e-1)" "unprognostic (9.45e-3)" "unprognostic (5.11e-2)" "unprognostic (1.73e-1)" "unprognostic (9.72e-2)" "prognostic unfavorable (5.28e-5)" "unprognostic (1.09e-1)" "unprognostic (7.92e-3)" "unprognostic (1.86e-2)" "unprognostic (3.90e-2)" "unprognostic (9.41e-2)" "unprognostic (9.72e-3)" "unprognostic (2.71e-1)" "unprognostic (3.88e-2)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" 177.4 116.1 91.7 160.2 96.5 402.9 142.7 100.1 113.8 128.6 98.4 198.2 142.3 131.3 99.8 162.3 124.8 131.7 117.0 95.2 108.8 158.8 153.5 154.1 167.9 115.5 103.7 105.9 82.5 128.4 59.6 170.3 108.4 108.3 185.4 95.9 103.8 107.5 119.9 132.0 156.9 175.0 107.4 157.5 159.9 64.2 102.2 157.7 110.6 120.9 216.8 194.8 114.9 127.1 341.9 146.4 272.2 222.0 295.0 306.4 274.2 347.3 318.8 365.5 336.2 178.0 374.5 253.1 272.8 416.7 136.2 210.7 241.1 369.3 431.1 332.4 180.1 438.1 184.5 225.4 259.1 388.5 350.5 285.6 396.6 341.0 195.2 234.7 535.6 157.8 250.8 273.4 430.2 135.6 242.9 307.5 170.2 242.9 179.3 199.6 297.6 243.3 316.2 301.3 183.4 175.8 293.4 228.7 263.4 296.3 242.3 219.1 466.3 265.3 265.2 349.3 207.8 148.6 355.9 305.8 234.5 419.3 277.6 244.3 200.6 255.1 142.4 282.3 144.3 108.0 152.0 146.7 162.3 103.4 109.5 143.5 308.3 145.0 352.2 107.2 157.4 244.8 91.7 96.5 100.1 113.8 95.2 108.8 115.5 103.7 108.4 107.4 102.2 127.1 502.1 60.9 51.8 20.9 301.0 450.6 385.5 266.0 136.1 119.1 281.1 179.6 86.9 231.6 168.0 312.6 18.8 349.6 470.1 434.9 375.6 441.3 38.0 350.5 356.5 307.7 300.4 243.0 58.5 441.9 499.6 225.2 152.4 425.8 163.6 138.2 277.0 230.9 439.2 106.0 71.0 315.4 187.2 585.4 875.2 41.3 157.8 443.4 423.4 53.4 654.9 102.5 286.3 41.7 72.9 570.5 369.7 177.1 192.9 323.1 283.1 578.2 176.2 65.2 236.7 174.2 308.3 155.3 116.2 176.6 556.6 551.6 379.2 178.6 286.7 469.6 CDK12 "CRK7, CRKR, CRKRS, KIAA0904" ENSG00000167258 "Cyclin dependent kinase 12" Q9NYV4 17 39461486-39564907 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 307.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008038, HPA073305" Supported Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA008038: AB_1078570, HPA073305: " "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (7.56e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.56e-3)" "unprognostic (2.37e-2)" "unprognostic (3.86e-2)" "unprognostic (3.00e-3)" "unprognostic (6.87e-3)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "unprognostic (9.10e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-2)" "unprognostic (5.32e-1)" 9.5 7.6 2.5 14.0 1.9 34.3 9.5 8.0 4.0 11.0 4.1 9.8 9.9 10.8 6.0 10.4 9.2 9.2 6.8 1.6 2.9 8.0 12.3 9.2 15.1 3.0 1.7 11.9 8.7 13.0 6.2 11.5 1.6 9.8 10.4 11.7 9.2 9.3 6.7 10.6 10.4 10.0 0.3 12.9 10.3 17.7 3.4 17.9 12.2 7.8 15.3 13.1 9.1 3.3 31.9 40.0 24.9 22.2 17.2 19.0 21.1 28.9 24.7 39.9 29.0 48.1 19.8 45.4 24.6 31.1 38.7 51.8 49.2 36.6 38.4 29.6 38.7 49.7 26.9 36.3 16.4 66.9 33.4 20.4 25.0 48.2 37.6 16.0 24.4 27.7 85.2 30.7 22.9 14.3 57.9 17.7 23.8 16.0 16.9 36.8 50.3 25.7 14.8 38.8 24.6 15.7 37.0 307.8 25.1 34.8 38.5 29.3 26.4 34.5 27.6 24.5 37.9 23.6 18.4 63.5 24.2 28.2 23.0 11.2 2.0 3.2 2.6 1.5 1.8 1.8 1.5 1.7 1.2 3.1 1.7 1.6 7.0 4.5 1.3 2.7 1.2 0.7 2.5 1.9 8.0 4.0 1.6 2.9 3.0 1.7 1.6 0.3 3.4 3.3 41.4 25.6 29.1 50.9 59.0 64.6 58.5 31.2 50.1 46.6 38.1 26.9 14.5 32.9 40.3 38.6 64.6 33.2 59.0 44.6 13.7 30.2 25.1 49.8 63.4 40.6 31.1 39.3 53.9 27.5 29.9 39.2 45.3 63.1 29.1 43.8 32.2 46.3 27.4 35.3 52.9 39.6 42.7 45.9 49.1 17.3 37.3 41.3 26.6 32.8 41.4 27.8 48.4 47.3 53.1 47.9 33.9 33.8 53.5 81.5 33.3 16.7 38.1 65.4 32.9 48.0 48.5 140.2 104.8 53.0 69.0 58.3 59.0 46.0 39.9 84.8 CDK5 PSSALRE ENSG00000164885 "Cyclin dependent kinase 5" Q00535 7 151053815-151057897 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008909, HPA064535" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB008909: , HPA064535: AB_2685280" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (4.22e-2)" "unprognostic (1.43e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-1)" "unprognostic (5.67e-3)" "unprognostic (1.05e-2)" "unprognostic (1.22e-1)" "unprognostic (5.78e-3)" "unprognostic (6.25e-3)" "unprognostic (3.35e-1)" "unprognostic (4.47e-2)" "unprognostic (1.46e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" "unprognostic (1.11e-1)" 6.3 16.8 50.2 9.4 53.2 11.2 8.6 44.9 65.8 8.6 40.0 9.3 10.9 6.7 24.9 10.2 8.2 9.5 9.8 57.5 50.9 13.5 12.5 8.3 9.8 48.6 45.3 4.5 9.5 22.8 14.7 8.6 48.4 8.8 9.9 11.3 9.6 10.2 8.5 9.5 8.6 10.4 43.2 9.4 7.9 4.9 50.1 14.2 10.0 7.2 11.6 8.8 6.0 50.9 31.9 40.8 37.3 59.7 48.8 36.1 17.8 24.4 41.7 47.9 40.3 31.2 31.0 34.7 71.3 31.8 63.5 23.5 67.8 40.6 22.6 24.9 43.3 38.2 32.4 30.7 31.6 29.0 64.4 37.9 28.7 39.0 13.5 62.8 38.8 57.6 36.3 24.0 50.7 68.4 76.4 57.9 39.3 57.2 80.5 38.9 14.8 41.5 46.2 27.9 23.0 97.8 30.9 37.7 43.8 36.0 18.6 25.9 22.7 42.2 10.3 31.2 39.2 52.1 61.4 13.7 66.4 46.5 75.8 18.9 39.4 20.1 13.5 46.2 11.1 13.3 12.8 13.6 44.7 12.8 9.8 11.8 5.7 19.9 36.4 26.9 31.9 23.8 50.2 53.2 44.9 65.8 57.5 50.9 48.6 45.3 48.4 43.2 50.1 50.9 7.6 0.0 6.0 1.6 6.2 3.6 8.2 18.0 6.2 12.1 9.6 10.4 3.1 8.6 14.7 11.0 2.1 26.8 5.4 8.0 39.2 21.4 0.8 14.9 10.9 8.9 9.0 12.2 5.8 18.9 12.3 7.6 9.7 9.3 30.5 23.6 7.9 11.1 41.9 0.0 6.4 8.9 18.3 21.9 6.2 1.3 4.7 16.6 10.6 1.9 19.9 12.6 12.3 1.5 3.7 22.8 15.0 11.3 12.4 4.3 20.2 35.7 14.4 7.1 6.6 4.5 13.1 3.9 11.2 11.4 6.3 9.0 7.3 14.2 9.5 9.0 CENPB ENSG00000125817 "Centromere protein B" P07199 20 3783851-3786740 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011626, HPA053507, HPA054405" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" Nucleoplasm "CAB011626: AB_726801, HPA053507: AB_2682173, HPA054405: AB_2682477" "unprognostic (2.01e-1)" "unprognostic (8.47e-3)" "unprognostic (2.61e-1)" "unprognostic (1.12e-2)" "unprognostic (1.75e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (6.09e-4)" "unprognostic (2.40e-2)" "unprognostic (3.27e-2)" "unprognostic (3.57e-1)" "unprognostic (1.48e-3)" "unprognostic (7.93e-2)" "unprognostic (2.78e-2)" "unprognostic (1.39e-1)" "unprognostic (2.68e-1)" "unprognostic (1.34e-1)" "unprognostic (2.46e-1)" 45.2 39.8 115.4 20.4 120.8 14.9 40.3 97.8 109.8 41.1 68.0 56.9 21.4 45.5 11.0 42.2 36.2 15.3 54.8 89.6 91.8 40.4 42.3 36.0 17.5 121.9 113.7 36.6 40.7 26.1 29.6 15.3 108.2 40.0 12.6 3.9 35.0 24.1 95.0 53.7 34.9 19.4 119.6 35.9 44.3 10.8 111.8 17.7 35.0 43.2 13.7 48.2 33.9 133.5 111.9 140.4 27.1 58.1 56.2 44.4 17.4 78.2 56.4 49.1 39.5 57.5 78.1 38.7 24.0 72.9 77.0 88.3 21.7 88.9 24.6 55.5 37.1 82.3 51.5 51.4 65.2 27.0 26.7 50.5 46.9 70.5 45.0 38.5 42.5 49.2 53.9 23.8 42.4 183.2 81.1 61.8 34.0 62.7 165.4 66.8 3.6 28.3 52.2 67.6 66.2 49.4 64.7 89.7 62.4 12.2 56.7 59.1 73.2 84.9 45.8 74.1 121.3 28.5 44.1 22.5 29.8 95.2 56.9 0.0 1.7 0.6 1.9 1.7 1.3 1.0 1.3 1.2 1.3 1.4 1.1 1.4 0.2 1.7 1.1 1.7 0.4 1.1 115.4 120.8 97.8 109.8 89.6 91.8 121.9 113.7 108.2 119.6 111.8 133.5 30.2 6.4 19.5 2.3 6.8 13.9 5.7 11.2 15.9 18.3 23.8 23.1 16.5 30.0 11.6 14.7 10.4 6.2 17.2 48.0 3.9 18.9 1.2 12.7 21.5 24.7 20.4 12.0 2.6 29.8 7.9 14.6 15.8 18.1 7.6 24.0 17.9 25.6 22.7 21.9 4.5 27.1 6.1 25.7 12.3 7.5 21.8 15.3 17.8 3.7 17.3 31.1 12.3 1.5 3.8 31.0 25.4 25.9 5.7 12.5 28.4 8.7 10.8 13.0 13.1 22.4 21.9 1.1 1.5 17.4 14.1 4.5 11.8 46.5 26.9 7.4 CHD4 "Mi-2b, Mi2-BETA" ENSG00000111642 "Chromodomain helicase DNA binding protein 4" Q14839 12 6570082-6614524 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA012008 Supported Enhanced Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA012008: AB_1846633" "unprognostic (6.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.71e-2)" "unprognostic (6.40e-3)" "unprognostic (8.99e-2)" "unprognostic (3.36e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "unprognostic (6.85e-2)" "unprognostic (3.15e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (3.33e-1)" "unprognostic (1.82e-1)" "unprognostic (9.84e-2)" "unprognostic (1.66e-1)" 34.5 45.6 22.9 38.6 30.7 44.4 31.9 24.6 30.1 39.4 20.6 45.7 26.5 47.8 44.9 35.4 37.7 31.1 41.4 19.7 26.1 39.3 31.6 35.3 46.3 27.3 29.2 40.9 37.7 58.3 33.5 42.2 28.0 28.4 35.4 44.9 33.8 44.1 50.0 45.8 35.5 49.9 22.6 39.0 38.5 34.2 29.6 90.7 54.6 38.7 56.6 42.2 34.4 27.4 86.7 79.7 187.6 72.1 76.6 84.7 110.4 92.9 93.4 102.3 93.5 130.6 66.6 184.9 36.0 107.5 66.1 76.0 179.1 104.5 135.7 139.9 92.7 258.5 122.0 83.3 67.1 207.2 119.1 82.9 51.7 99.1 68.7 128.2 122.2 101.6 209.0 91.0 98.7 111.8 196.6 67.8 184.7 82.5 72.7 166.4 114.9 103.6 64.2 101.6 88.8 114.6 121.1 136.0 92.9 205.4 61.3 121.3 114.4 103.4 217.4 76.3 111.5 144.0 91.8 230.2 68.7 125.8 79.5 12.3 6.8 8.7 9.3 7.7 9.6 8.8 8.4 9.3 6.9 11.3 10.6 10.3 10.8 12.2 8.0 14.4 15.9 5.6 22.9 30.7 24.6 30.1 19.7 26.1 27.3 29.2 28.0 22.6 29.6 27.4 68.2 60.9 119.7 56.2 82.8 68.6 47.4 42.4 76.2 109.9 77.5 61.2 132.9 58.6 67.2 88.3 70.9 48.2 106.0 58.1 13.7 84.6 76.4 128.1 153.3 78.9 97.1 64.4 26.1 71.9 46.1 67.7 47.9 123.7 85.9 73.0 56.0 69.2 69.0 139.7 21.4 66.6 54.9 51.9 78.3 59.1 65.9 68.9 48.0 25.3 66.7 71.4 56.7 24.6 55.5 95.8 36.4 74.4 69.0 49.4 45.8 38.3 82.1 57.8 52.6 112.1 98.1 102.6 111.6 78.9 67.6 68.0 85.1 83.7 72.1 47.4 CHTOP "C1orf77, DKFZP547E1010, FOP, SRAG" ENSG00000160679 "Chromatin target of PRMT1" Q9Y3Y2 1 153633982-153646306 "Plasma proteins, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028647, HPA030540" Approved Enhanced "Nuclear speckles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA028647: AB_10602699, HPA030540: AB_2673516" "unprognostic (2.72e-1)" "unprognostic (2.41e-1)" "unprognostic (3.41e-2)" "unprognostic (6.77e-2)" "unprognostic (6.80e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (8.65e-2)" "prognostic unfavorable (4.08e-4)" "unprognostic (9.16e-2)" "unprognostic (2.20e-1)" "unprognostic (7.30e-3)" "prognostic unfavorable (2.02e-4)" "unprognostic (1.58e-2)" "unprognostic (4.19e-2)" "unprognostic (2.70e-1)" "prognostic favorable (2.69e-4)" 42.4 44.8 48.1 36.5 54.1 62.5 44.2 54.7 56.0 52.5 48.3 44.2 30.3 45.2 36.2 50.3 47.5 21.9 63.3 47.8 51.1 66.5 54.8 39.3 46.6 51.9 50.7 55.2 63.4 35.9 48.7 33.4 52.2 48.4 32.7 59.9 44.4 29.6 124.4 52.6 46.8 30.5 50.0 65.4 47.9 37.6 49.6 65.7 55.8 68.4 44.4 45.1 47.9 63.5 74.3 63.9 106.2 65.0 45.2 33.1 84.3 51.2 47.0 71.3 61.2 71.6 72.9 83.5 75.6 48.0 46.6 66.8 103.4 74.7 46.9 97.8 95.7 65.5 102.2 60.0 56.1 101.8 78.8 38.5 84.8 69.0 97.5 59.2 57.7 89.4 82.1 62.2 54.1 94.3 109.8 102.6 123.6 106.9 79.1 67.5 65.0 92.5 69.8 100.5 64.3 74.5 54.6 77.8 91.6 69.9 83.7 138.6 50.0 47.7 70.4 60.7 83.8 86.2 77.8 95.5 50.1 81.9 56.8 84.9 42.9 40.9 46.0 44.8 46.2 46.2 45.3 45.3 54.4 43.3 45.2 41.0 30.8 35.1 43.0 41.7 51.9 46.4 48.1 54.1 54.7 56.0 47.8 51.1 51.9 50.7 52.2 50.0 49.6 63.5 46.4 32.1 37.3 32.3 50.1 63.0 103.6 59.7 37.5 40.8 45.6 33.5 74.1 57.2 43.5 53.3 33.3 91.7 47.7 49.2 50.9 69.5 34.9 50.6 42.6 54.2 60.3 81.9 16.1 64.8 121.9 47.1 42.3 63.4 46.3 59.7 43.9 41.2 69.7 43.7 17.6 56.4 42.7 48.9 38.2 18.0 44.7 40.9 35.6 14.0 69.3 44.0 52.5 16.6 40.1 61.3 58.1 42.2 48.2 101.8 48.4 49.0 33.2 57.5 19.7 34.9 59.7 125.2 115.2 46.5 61.7 128.6 45.7 57.9 52.3 110.2 CLK3 ENSG00000179335 "CDC like kinase 3" P49761 15 74598500-74645414 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046817 Approved Supported "Nucleoplasm,Intermediate filaments" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Intermediate filaments" "HPA046817: AB_10964124" "unprognostic (4.10e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (2.05e-6)" "unprognostic (1.91e-3)" "unprognostic (7.91e-2)" "unprognostic (5.76e-2)" "unprognostic (1.46e-1)" "unprognostic (1.30e-2)" "unprognostic (1.95e-1)" "unprognostic (2.54e-1)" "unprognostic (8.14e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "unprognostic (9.73e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-2)" 35.9 28.7 30.3 26.5 31.8 112.4 34.6 36.4 35.9 36.7 32.8 36.6 28.9 32.3 25.9 38.6 31.3 32.7 28.3 30.2 31.2 30.0 29.4 34.0 37.7 32.8 31.6 38.4 33.9 35.3 32.3 31.6 32.5 31.9 21.8 33.1 36.1 29.7 50.7 41.7 33.7 26.2 29.5 41.7 35.1 44.4 32.2 55.8 32.3 52.1 30.3 37.8 33.8 35.4 56.7 35.1 45.5 25.6 57.2 43.4 35.8 37.7 59.2 52.7 64.3 47.9 36.4 51.2 27.2 33.9 73.5 39.0 85.4 36.3 34.3 73.2 46.9 63.0 52.0 33.6 90.7 17.2 46.6 54.8 71.0 69.4 57.4 64.0 58.6 51.0 31.3 36.2 31.1 39.9 50.9 57.3 29.1 55.7 24.6 40.7 21.8 33.7 41.1 40.3 25.5 29.9 30.2 33.0 34.3 34.7 31.4 33.8 27.3 31.0 23.7 19.7 50.2 59.0 51.8 42.2 27.2 82.4 40.1 74.2 65.5 90.0 68.9 74.1 68.2 71.0 73.6 71.9 61.3 78.8 74.4 70.9 115.9 90.7 97.7 69.5 87.7 85.9 30.3 31.8 36.4 35.9 30.2 31.2 32.8 31.6 32.5 29.5 32.2 35.4 29.8 6.4 38.4 14.0 34.1 44.9 44.9 41.6 26.2 35.5 22.8 15.9 18.6 28.6 35.1 12.9 56.3 27.7 41.8 46.7 31.3 34.2 83.6 25.8 19.9 28.6 29.3 31.5 6.6 24.2 46.2 24.5 37.8 41.5 21.5 27.4 21.4 13.4 27.5 28.6 7.9 34.7 42.7 23.3 34.4 19.8 27.7 28.4 28.4 6.5 29.5 18.0 29.9 7.1 9.6 30.8 52.0 20.3 26.6 38.9 35.5 18.6 23.4 42.6 13.1 20.4 35.8 45.4 21.4 21.0 41.9 58.6 40.1 20.4 28.1 63.5 CLPP ENSG00000125656 "Caseinolytic mitochondrial matrix peptidase proteolytic subunit" Q16740 19 6361531-6370242 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010649 Supported Supported Mitochondria NA NA 8500 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA010649: AB_1078538" "unprognostic (2.28e-1)" "unprognostic (7.14e-2)" "unprognostic (2.82e-1)" "unprognostic (4.34e-2)" "unprognostic (2.17e-2)" "unprognostic (1.15e-2)" "unprognostic (6.17e-3)" "unprognostic (7.43e-2)" "unprognostic (2.76e-1)" "unprognostic (1.31e-1)" "prognostic favorable (6.50e-4)" "unprognostic (1.21e-1)" "unprognostic (5.65e-2)" "unprognostic (6.97e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.86e-3)" 48.6 65.8 52.0 41.5 51.5 42.9 45.1 52.2 63.8 39.1 58.0 46.6 47.4 41.1 17.8 56.1 40.1 20.8 78.0 50.9 52.7 60.5 90.7 39.7 47.7 52.8 52.4 38.5 53.6 36.6 44.5 25.4 49.5 41.0 22.9 15.6 48.3 31.2 146.8 47.5 43.6 25.1 51.8 45.6 55.6 45.2 54.5 45.2 36.1 59.3 35.6 44.6 37.9 53.9 146.7 98.2 61.2 113.9 38.7 54.8 62.4 76.9 59.5 112.2 102.5 87.2 48.9 124.1 122.8 61.3 61.1 83.1 63.5 109.1 38.5 133.8 189.3 95.8 82.2 122.9 106.6 90.7 129.8 73.4 74.4 78.9 82.9 69.7 113.9 188.5 97.5 174.5 72.3 192.8 153.1 104.5 93.2 100.6 207.8 108.6 73.2 206.2 81.2 79.4 99.3 95.9 48.9 123.8 133.0 36.7 67.3 130.6 76.9 70.5 69.7 180.7 156.0 235.4 225.3 137.2 103.5 132.9 117.3 29.4 82.6 47.8 112.0 79.6 133.5 119.5 159.4 139.6 102.4 131.5 138.4 137.4 62.1 126.5 55.5 155.5 207.2 162.6 52.0 51.5 52.2 63.8 50.9 52.7 52.8 52.4 49.5 51.8 54.5 53.9 39.6 22.4 35.2 8.1 45.9 44.9 59.5 90.8 38.1 31.0 47.6 57.9 45.8 55.8 46.2 44.1 12.5 72.2 43.7 56.0 144.8 88.8 105.5 27.6 43.1 51.6 35.3 54.9 5.4 96.6 113.6 42.4 36.2 35.0 26.0 63.1 61.8 89.6 81.3 21.9 7.5 50.9 54.9 38.9 35.0 229.8 42.6 38.7 55.2 4.7 70.6 46.6 46.4 4.5 9.5 101.9 67.7 43.2 82.4 89.5 110.9 189.0 44.5 24.6 13.1 30.0 79.9 67.7 48.1 56.5 37.1 57.7 65.3 95.1 65.4 65.4 CLTA Lca ENSG00000122705 "Clathrin light chain A" P09496 9 36190856-36304781 "Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1299.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002665, HPA050918, HPA054667" Enhanced Enhanced Vesicles,Endosomes,Lysosomes NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Vesicles, Endosomes, Lysosomes" "CAB002665: , HPA050918: AB_2681273, HPA054667: AB_2682565" "prognostic favorable (5.64e-4)" "unprognostic (7.62e-2)" "unprognostic (9.22e-2)" "unprognostic (8.45e-3)" "unprognostic (1.71e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (9.46e-5)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (1.92e-3)" "unprognostic (7.27e-2)" "unprognostic (2.15e-1)" "unprognostic (1.23e-3)" "unprognostic (5.92e-2)" "unprognostic (1.56e-1)" "prognostic favorable (1.01e-4)" "unprognostic (4.98e-2)" 172.8 174.2 131.6 80.8 139.1 67.2 165.6 144.7 165.1 170.9 137.5 163.3 107.9 165.6 100.7 207.1 158.9 64.4 98.1 133.3 143.8 236.0 146.8 146.2 84.1 145.1 138.5 205.6 164.3 104.3 139.3 124.4 151.4 145.0 108.6 84.8 162.8 71.2 87.7 163.2 136.0 84.9 141.6 153.0 161.4 108.5 141.7 85.2 160.1 51.5 93.4 150.9 158.4 151.5 326.3 257.2 188.4 146.3 270.0 269.8 302.6 328.5 248.2 258.1 301.5 194.2 143.9 243.8 177.0 220.9 460.7 136.2 238.8 228.2 238.4 166.0 193.1 187.5 255.0 199.8 359.4 201.0 166.5 297.3 250.5 297.4 234.3 241.0 329.6 129.3 166.0 126.4 399.0 113.3 182.2 254.8 301.8 218.8 360.3 173.3 124.8 142.1 353.7 229.1 146.1 245.3 137.3 160.0 289.4 220.2 146.9 244.2 418.4 209.4 234.0 240.3 347.9 83.0 208.9 259.5 256.9 278.0 188.9 142.2 221.7 115.4 97.1 239.6 101.9 121.0 104.9 100.2 222.6 119.6 92.9 82.0 86.7 96.2 191.8 192.2 162.9 209.4 131.6 139.1 144.7 165.1 133.3 143.8 145.1 138.5 151.4 141.6 141.7 151.5 291.5 128.2 143.9 14.4 105.9 197.3 274.3 374.3 169.0 139.4 274.0 315.0 51.5 217.3 247.4 180.3 60.5 958.0 140.1 349.3 463.7 480.5 51.9 241.5 174.3 244.0 183.8 154.8 28.5 335.6 469.1 187.5 142.2 182.7 73.5 198.4 312.7 170.6 903.7 92.5 30.4 350.5 248.2 391.7 172.0 97.6 262.9 249.3 195.7 20.6 343.5 282.8 117.4 16.1 49.0 465.2 426.4 215.5 97.7 320.5 411.5 651.7 304.7 127.3 177.5 170.0 310.4 288.0 216.8 210.9 193.2 1299.5 103.7 281.6 380.0 360.4 CLTC "CLTCL2, Hc" ENSG00000141367 "Clathrin heavy chain" Q00610 17 59619689-59696956 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Cell cycle, Cell division, Mitosis" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010389, CAB011571, CAB017155, HPA059143" Approved Enhanced "Vesicles,Endosomes,Lysosomes,Mitotic spindle,Cytosol" Yes No 14000000 "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Vesicles, Endosomes, Lysosomes" "Mitotic spindle, Cytosol" "CAB010389: AB_2083184, CAB011571: AB_2083165, CAB017155: , HPA059143: AB_2683924" "unprognostic (1.56e-1)" "prognostic unfavorable (7.35e-4)" "prognostic favorable (7.65e-4)" "unprognostic (1.03e-1)" "unprognostic (2.62e-1)" "unprognostic (5.23e-3)" "prognostic unfavorable (5.54e-4)" "unprognostic (1.11e-1)" "unprognostic (6.43e-2)" "unprognostic (1.09e-1)" "unprognostic (3.34e-2)" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "unprognostic (9.22e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.02e-4)" 105.4 95.2 42.1 89.7 54.9 96.3 81.6 67.3 103.9 92.3 36.7 121.7 74.1 83.1 126.4 82.1 67.8 88.9 90.7 60.7 65.1 125.5 117.7 82.1 75.5 95.5 52.4 73.2 56.8 186.8 51.6 139.6 95.2 97.8 128.3 163.6 68.6 104.2 88.4 81.3 73.3 121.0 43.8 78.8 91.2 71.3 68.2 76.0 114.1 83.9 86.8 101.1 51.6 55.0 293.3 426.1 207.6 207.0 345.8 280.5 240.0 305.7 321.7 268.2 278.9 264.7 175.2 200.6 340.1 436.4 296.9 186.2 313.6 255.1 356.2 214.4 166.8 328.2 248.8 414.0 262.3 228.5 182.3 266.9 154.6 408.0 262.3 211.4 302.0 99.9 334.4 280.4 429.1 511.1 135.6 65.1 179.6 263.3 248.2 118.7 343.6 244.9 297.5 404.1 184.1 216.7 188.3 122.9 180.4 270.5 290.3 142.3 385.6 492.4 287.9 237.0 317.8 213.3 320.3 181.4 357.7 151.6 305.3 16.6 33.1 21.3 17.5 36.3 21.7 13.7 16.1 19.2 36.5 12.9 13.4 15.0 19.9 18.9 32.5 22.8 22.1 23.3 42.1 54.9 67.3 103.9 60.7 65.1 95.5 52.4 95.2 43.8 68.2 55.0 62.6 99.3 107.9 80.3 46.3 63.9 44.4 75.6 28.5 91.9 58.5 34.7 77.9 71.4 103.3 77.3 60.5 109.1 60.7 184.0 27.4 76.2 23.3 95.5 95.6 79.7 120.6 115.9 137.7 97.7 47.7 84.5 99.4 106.1 68.4 75.5 120.7 185.4 182.5 85.8 135.9 120.7 77.3 195.0 93.2 77.2 74.0 128.3 53.4 79.6 102.8 53.9 38.1 73.4 124.2 106.2 76.1 93.6 83.0 86.3 102.7 132.4 128.0 65.2 78.9 66.0 82.8 52.7 38.0 60.5 79.3 107.9 45.9 81.3 127.8 91.6 CNBP "CNBP1, DM2, RNF163, ZCCHC22, ZNF9" ENSG00000169714 "CCHC-type zinc finger nucleic acid binding protein" P62633 3 129167827-129183922 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063097 Approved Nucleoplasm,Cytosol NA NA 160000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA063097: AB_2684939" "unprognostic (1.74e-1)" "unprognostic (3.11e-2)" "unprognostic (4.84e-1)" "unprognostic (3.35e-2)" "unprognostic (6.28e-2)" "unprognostic (7.38e-2)" "unprognostic (7.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (6.39e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (4.72e-3)" "unprognostic (4.62e-3)" "unprognostic (1.89e-1)" "unprognostic (2.03e-1)" "unprognostic (2.51e-1)" "unprognostic (1.58e-1)" 292.7 308.2 175.2 181.1 184.0 254.1 274.6 198.6 211.3 295.9 175.7 314.1 198.5 285.8 197.6 264.6 275.7 195.1 487.2 170.6 184.3 231.6 433.7 258.3 251.0 182.7 175.1 385.8 307.4 277.9 169.5 214.3 187.1 256.6 219.0 231.8 250.8 282.4 1207.6 288.0 199.2 234.9 195.6 200.7 262.1 131.2 181.9 254.2 261.8 797.9 250.7 317.5 269.2 211.7 452.7 266.4 369.9 294.6 355.2 303.9 294.9 344.2 535.7 362.2 412.4 389.2 305.7 589.8 292.2 318.1 269.6 328.3 484.3 396.4 484.6 404.5 357.9 569.2 251.7 420.2 355.7 622.4 314.5 295.5 449.2 254.8 897.8 247.6 324.1 328.1 437.6 391.9 384.0 538.9 578.6 454.1 452.7 399.7 439.1 502.4 343.4 707.7 379.1 425.4 501.2 402.8 271.5 263.0 766.3 214.4 305.6 421.3 347.9 268.4 266.2 374.1 353.7 367.3 365.4 932.3 277.3 419.2 362.4 1077.7 810.5 930.9 551.8 596.8 699.0 691.0 658.8 595.3 552.8 603.8 700.3 610.5 1102.3 601.1 485.5 320.4 704.3 2029.8 175.2 184.0 198.6 211.3 170.6 184.3 182.7 175.1 187.1 195.6 181.9 211.7 253.7 259.6 263.9 27.1 292.8 524.7 417.0 262.9 259.6 153.7 177.5 272.5 608.0 141.5 235.1 79.1 33.3 252.3 188.1 143.9 373.7 226.9 36.0 141.4 195.1 267.5 171.3 246.5 28.2 290.7 396.6 309.4 142.8 172.8 314.5 173.0 167.0 138.5 246.5 92.5 33.7 178.6 140.4 194.4 463.0 42.9 316.0 232.4 318.4 35.6 392.7 350.3 236.9 32.6 42.8 230.1 158.0 319.7 311.7 405.1 196.5 237.4 164.8 153.8 263.0 343.6 571.0 305.2 271.5 286.5 586.7 291.7 304.2 277.7 213.6 376.2 CNIH4 HSPC163 ENSG00000143771 "Cornichon family AMPA receptor auxiliary protein 4" Q9P003 1 224356858-224379459 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 320.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044268 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" "HPA044268: AB_10965330" "unprognostic (2.01e-1)" "unprognostic (1.34e-3)" "unprognostic (1.56e-1)" "unprognostic (1.66e-1)" "unprognostic (1.40e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (4.47e-3)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (5.96e-3)" "prognostic unfavorable (4.61e-4)" "unprognostic (2.51e-1)" "prognostic unfavorable (4.27e-6)" "unprognostic (3.15e-3)" "unprognostic (2.20e-1)" "unprognostic (1.42e-3)" "unprognostic (1.63e-2)" 21.9 19.4 14.6 12.1 15.3 26.9 19.7 15.1 17.4 15.5 17.8 19.9 16.6 18.4 12.1 23.5 16.0 12.1 18.3 14.7 16.0 19.4 18.3 21.4 9.3 15.5 15.1 15.6 11.8 18.9 10.5 18.5 15.9 13.2 15.5 14.8 14.4 15.6 25.1 19.5 17.8 19.2 14.9 15.1 16.5 10.0 14.8 9.7 12.3 19.1 11.3 20.8 18.3 15.2 81.1 110.4 51.6 46.3 91.6 59.5 42.5 54.4 50.7 55.8 51.1 110.7 93.7 24.0 86.5 54.9 60.5 94.6 95.4 59.9 58.6 29.8 101.1 20.6 70.7 59.0 79.6 40.9 38.9 61.7 80.8 69.7 91.0 55.9 74.8 42.3 49.3 31.1 66.8 62.8 17.6 37.0 68.2 106.3 63.0 19.1 94.8 26.4 92.4 89.9 13.1 43.9 82.4 90.1 69.3 64.6 69.4 96.2 71.9 51.5 44.6 64.2 112.6 13.4 18.7 23.9 63.5 55.3 56.1 54.5 60.0 72.7 36.7 106.6 35.4 25.8 47.8 42.2 52.3 23.9 38.1 41.8 48.4 31.6 153.7 17.5 36.0 58.1 14.6 15.3 15.1 17.4 14.7 16.0 15.5 15.1 15.9 14.9 14.8 15.2 68.4 125.0 84.9 9.8 27.3 66.5 137.0 320.0 42.7 20.4 49.5 74.0 117.8 61.5 160.2 53.3 29.2 145.9 29.7 138.7 29.4 140.3 16.2 61.3 62.6 76.2 15.6 56.2 15.4 125.2 180.6 90.9 27.5 60.8 32.3 54.0 58.5 70.1 107.6 20.2 14.2 38.5 120.1 124.4 60.0 10.9 65.9 86.5 58.7 12.2 72.9 52.9 45.3 13.6 16.9 132.9 116.7 65.1 28.1 148.7 136.2 101.5 127.7 34.3 85.5 45.5 196.5 145.6 63.4 73.0 86.9 161.2 50.4 45.7 72.7 149.0 CNOT3 "KIAA0691, LENG2, NOT3, NOT3H" ENSG00000088038 "CCR4-NOT transcription complex subunit 3" O75175 19 54137749-54155681 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 213.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006408 Approved Approved Cytosol NA NA 39000 "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA006408: AB_1078543" "unprognostic (1.23e-1)" "unprognostic (2.54e-1)" "unprognostic (1.75e-2)" "unprognostic (1.40e-1)" "unprognostic (4.86e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (9.06e-2)" "unprognostic (1.43e-2)" "unprognostic (2.65e-2)" "unprognostic (9.30e-3)" "unprognostic (4.08e-3)" "prognostic unfavorable (2.77e-4)" "unprognostic (2.18e-1)" "unprognostic (1.73e-1)" "unprognostic (2.11e-1)" "unprognostic (2.66e-2)" 21.3 29.0 11.3 17.5 11.6 19.6 22.9 13.7 14.1 27.0 7.6 27.1 16.8 27.3 19.6 26.8 27.5 12.5 19.4 10.9 14.2 24.8 25.3 21.2 20.4 12.0 9.5 30.5 28.3 17.5 34.0 19.2 10.4 27.6 13.2 18.0 26.1 18.7 24.1 30.3 25.1 16.8 7.1 29.9 26.6 35.2 10.8 23.6 30.0 11.0 18.1 25.6 25.5 12.0 45.5 69.1 69.7 40.8 25.4 25.2 48.0 39.2 68.4 52.2 45.9 44.2 36.2 53.1 24.8 46.1 41.8 44.1 77.3 39.2 53.1 55.5 213.4 81.7 44.5 39.1 43.3 47.7 54.9 32.1 35.8 46.7 77.3 37.1 41.5 39.0 61.8 47.9 38.3 53.3 63.8 27.9 43.1 87.7 52.4 57.8 52.4 35.7 33.7 85.4 44.9 37.2 75.1 54.6 25.8 50.6 31.3 50.2 37.8 47.3 50.3 23.4 54.4 46.3 54.1 71.2 38.7 37.1 48.0 0.9 1.6 3.1 1.6 1.0 1.2 1.3 1.1 1.5 1.4 1.4 1.2 1.3 4.2 0.8 1.4 3.4 1.2 2.0 11.3 11.6 13.7 14.1 10.9 14.2 12.0 9.5 10.4 7.1 10.8 12.0 14.2 12.8 7.4 10.7 17.4 9.9 17.2 15.7 18.8 17.5 14.0 13.8 2.0 12.8 14.4 7.3 16.7 28.8 20.5 17.8 9.8 14.8 19.9 20.9 19.6 13.2 14.4 13.3 6.1 14.5 28.5 13.6 20.9 21.4 3.8 22.7 12.5 8.5 16.2 16.8 7.0 17.1 18.3 9.7 6.9 6.6 17.1 13.1 5.4 4.7 15.6 12.0 16.5 5.0 8.0 15.1 23.9 9.4 20.8 21.4 14.9 9.0 14.3 18.5 6.6 17.3 17.9 49.2 47.9 16.6 9.9 50.1 15.4 21.6 13.2 17.3 CNOT4 "CLONE243, NOT4, NOT4H" ENSG00000080802 "CCR4-NOT transcription complex subunit 4" O95628 7 135361795-135510127 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005737 Approved NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA005737: AB_1078544" "unprognostic (9.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "unprognostic (5.47e-2)" "unprognostic (3.61e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (2.82e-2)" "unprognostic (4.18e-2)" "prognostic favorable (1.61e-4)" "unprognostic (9.08e-2)" "unprognostic (1.00e-2)" "prognostic favorable (7.67e-6)" "unprognostic (1.01e-1)" "unprognostic (6.31e-2)" "unprognostic (2.23e-1)" "unprognostic (9.33e-2)" 9.2 8.9 10.3 8.2 11.0 7.9 8.3 16.2 14.0 11.3 5.9 8.7 7.4 11.1 9.1 10.1 10.4 8.9 12.5 10.7 13.7 10.0 10.4 8.7 10.1 9.4 10.6 15.4 9.2 13.4 6.5 10.7 9.4 9.5 8.4 15.4 11.4 9.4 21.7 10.2 7.7 11.0 7.7 9.5 8.1 17.6 10.2 11.9 13.6 22.2 11.5 9.0 8.7 11.2 15.4 14.3 14.3 19.3 23.3 18.4 10.3 16.9 18.3 14.1 17.4 12.4 15.4 15.2 14.3 15.6 20.0 14.2 18.3 12.8 20.0 17.3 14.1 12.6 11.9 11.0 12.9 14.4 14.5 14.2 16.0 18.1 11.1 16.2 14.7 10.7 22.4 11.8 21.0 19.2 19.8 21.2 18.9 14.1 11.9 12.7 14.1 16.6 16.6 14.0 15.1 17.7 19.7 21.7 11.6 13.2 13.5 15.8 20.0 17.0 10.0 15.9 18.5 18.1 18.2 21.5 17.2 16.4 23.2 23.7 10.5 14.6 12.4 10.8 13.6 9.8 10.4 10.4 9.4 10.7 11.1 10.5 9.4 15.8 13.1 7.5 9.7 9.2 10.3 11.0 16.2 14.0 10.7 13.7 9.4 10.6 9.4 7.7 10.2 11.2 53.9 22.4 43.0 83.9 63.0 67.7 76.3 54.0 45.5 50.6 49.7 58.2 42.7 31.5 44.3 36.8 106.3 31.5 60.9 30.0 70.5 32.9 30.7 31.3 56.7 48.3 40.7 50.9 103.7 20.7 22.5 58.4 35.2 45.1 62.6 46.1 40.0 25.0 25.5 55.5 94.0 30.2 30.5 28.1 61.0 20.7 65.3 33.4 42.7 88.1 61.0 69.1 68.0 119.6 102.8 32.4 31.2 69.2 58.9 73.0 32.0 56.2 35.4 72.4 19.7 83.8 75.3 113.4 75.7 42.1 75.7 44.6 61.6 45.9 29.3 89.4 COA7 "C1orf163, FLJ12439, RESA1, SELRC1" ENSG00000162377 "Cytochrome c oxidase assembly factor 7 (putative)" Q96BR5 1 52684449-52698347 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028154, HPA029926" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Mitochondria" "HPA028154: AB_10600656, HPA029926: AB_10602173" "unprognostic (1.88e-1)" "unprognostic (1.02e-1)" "unprognostic (1.29e-2)" "prognostic unfavorable (8.55e-4)" "unprognostic (2.30e-2)" "unprognostic (5.12e-2)" "prognostic unfavorable (7.01e-5)" "unprognostic (1.14e-1)" "unprognostic (2.27e-2)" "unprognostic (1.24e-1)" "unprognostic (4.07e-2)" "unprognostic (7.42e-2)" "unprognostic (2.49e-1)" "prognostic favorable (4.35e-4)" "unprognostic (1.18e-1)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" 6.8 4.8 5.7 5.4 5.5 3.9 7.3 5.2 6.5 4.6 2.5 7.9 7.7 5.5 4.2 6.3 4.6 3.5 5.5 5.3 5.0 9.6 12.1 3.9 4.0 4.7 4.5 3.7 10.7 5.2 2.5 5.2 4.8 3.6 7.5 4.3 3.3 3.6 16.0 6.5 5.6 5.9 3.9 3.9 5.1 3.2 5.1 2.7 7.1 20.4 4.5 5.5 3.5 5.7 26.0 14.5 13.0 21.1 20.7 17.9 28.6 19.1 15.9 23.4 19.5 18.2 9.0 59.4 12.7 11.4 29.6 19.5 31.9 27.1 30.4 18.4 31.9 49.9 22.5 20.9 25.5 49.7 16.4 19.8 23.5 26.6 33.0 10.3 16.3 16.6 46.5 10.0 17.9 17.3 17.0 25.3 57.7 27.7 40.8 32.9 44.6 43.2 20.7 25.9 29.2 15.4 27.9 35.0 36.3 18.3 20.5 33.4 18.2 18.3 24.0 25.5 26.7 21.2 57.0 27.2 8.5 35.4 15.2 1.6 2.9 0.4 1.1 4.3 1.5 1.8 1.2 1.1 3.0 0.7 1.0 1.1 0.6 1.1 2.2 1.1 0.7 1.6 5.7 5.5 5.2 6.5 5.3 5.0 4.7 4.5 4.8 3.9 5.1 5.7 6.0 6.4 12.4 0.7 4.5 11.5 31.2 7.1 9.6 8.8 6.1 5.2 13.2 10.0 7.1 3.7 4.2 17.1 1.7 11.4 27.4 11.9 0.5 3.2 12.3 8.8 2.4 5.5 1.6 13.3 17.0 7.8 5.1 3.4 0.0 8.0 3.6 13.7 13.7 16.8 2.1 7.0 6.1 4.7 3.5 0.8 7.5 7.0 1.8 1.9 8.7 6.8 4.1 3.5 1.5 11.0 7.0 7.5 9.9 19.3 5.0 20.1 2.6 10.2 6.6 11.4 14.0 4.6 13.0 9.7 12.9 16.6 4.2 10.5 10.5 17.8 COMMD1 "C2orf5, MGC27155, MURR1" ENSG00000173163 "Copper metabolism domain containing 1" Q8N668 2 61888724-62147247 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034633, HPA049223" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA034633: AB_10601800, HPA049223: AB_2680680" "unprognostic (6.08e-2)" "unprognostic (2.34e-2)" "unprognostic (2.83e-1)" "unprognostic (1.43e-2)" "unprognostic (2.30e-1)" "unprognostic (1.22e-2)" "unprognostic (5.58e-2)" "unprognostic (1.07e-1)" "unprognostic (4.93e-1)" "unprognostic (3.41e-2)" "unprognostic (2.26e-1)" "unprognostic (2.07e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-2)" "unprognostic (1.27e-1)" "unprognostic (5.51e-2)" "unprognostic (2.77e-1)" 20.8 26.4 22.2 21.9 23.4 20.4 27.0 25.2 33.0 23.0 22.9 18.6 22.6 20.0 30.1 24.8 20.9 20.2 54.7 23.5 22.9 31.2 35.9 18.7 23.5 22.1 22.1 21.3 24.1 24.4 14.8 26.5 22.6 22.2 22.6 20.1 33.5 20.2 35.2 22.2 14.9 29.9 22.4 20.6 19.2 24.4 22.2 20.7 28.1 38.1 25.5 23.9 19.8 24.1 23.2 29.1 32.0 25.4 41.2 41.2 27.4 27.2 45.6 53.7 37.9 50.1 20.4 40.4 22.3 50.8 45.8 17.6 18.0 33.1 55.8 43.9 21.1 31.5 16.3 56.0 35.1 49.6 23.8 34.6 37.7 26.1 30.8 39.2 54.6 23.2 19.6 64.3 56.7 43.6 38.6 87.4 27.9 19.0 39.0 27.1 42.4 46.7 49.3 25.0 19.5 21.7 30.7 50.9 28.6 31.8 32.4 21.4 25.9 48.1 41.5 30.2 42.4 26.6 22.9 48.6 26.5 42.8 42.8 62.4 96.2 48.4 63.0 86.5 63.4 91.8 71.5 72.0 117.3 84.7 68.1 73.8 8.1 91.1 78.4 109.5 88.8 110.8 22.2 23.4 25.2 33.0 23.5 22.9 22.1 22.1 22.6 22.4 22.2 24.1 53.0 35.3 33.8 56.8 38.2 54.4 73.8 98.7 47.8 35.4 47.0 72.4 176.7 41.5 57.3 35.0 10.4 127.3 37.3 27.4 129.1 71.5 195.6 50.6 52.1 53.2 21.6 43.1 91.9 65.1 75.5 67.6 32.1 47.2 57.7 60.4 52.5 72.4 101.7 28.6 78.4 29.8 63.1 36.0 81.3 163.5 41.3 46.3 83.6 71.2 118.6 45.3 30.9 89.5 109.7 57.1 37.1 49.7 71.5 48.9 49.0 192.3 49.1 33.2 32.9 57.6 97.2 124.5 58.7 49.6 61.7 147.2 38.6 81.6 30.1 64.0 COPB1 COPB ENSG00000129083 "COPI coat complex subunit beta 1" P53618 11 14443440-14500027 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012338, HPA043954, HPA064403" Supported Enhanced "Golgi apparatus,Vesicles,Cytosol" NA NA 330000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles, Cytosol" "CAB012338: AB_726922, HPA043954: AB_2678746, HPA064403: AB_2685258" "unprognostic (2.35e-1)" "unprognostic (1.02e-3)" "unprognostic (1.36e-2)" "unprognostic (4.76e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (6.91e-4)" "prognostic unfavorable (5.63e-7)" "unprognostic (4.69e-3)" "unprognostic (3.42e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (8.04e-4)" "unprognostic (8.94e-2)" "unprognostic (1.78e-2)" "unprognostic (3.02e-2)" "unprognostic (8.00e-2)" "unprognostic (3.87e-1)" "unprognostic (1.69e-2)" 48.1 47.1 19.9 55.0 21.8 79.8 62.6 26.2 25.3 64.9 44.7 59.8 57.7 52.6 69.3 46.7 49.2 54.9 43.7 20.1 23.6 65.3 73.6 49.9 59.1 24.2 21.8 49.1 59.2 67.6 48.4 69.2 23.7 66.9 67.1 39.3 67.5 53.8 33.1 36.6 58.8 61.1 23.5 46.3 59.7 46.8 23.0 68.1 81.0 38.1 64.5 60.4 40.0 27.6 134.9 113.6 118.6 89.4 193.1 221.3 95.9 199.2 206.5 173.1 202.0 89.1 203.5 130.1 87.1 252.9 164.6 144.7 134.6 133.3 212.1 122.7 114.0 138.3 74.3 135.8 171.3 128.9 134.4 156.3 172.4 116.0 217.8 158.9 183.7 71.6 104.5 103.8 221.1 101.6 117.2 78.7 61.7 163.3 123.1 94.9 163.1 89.0 156.1 123.3 75.6 81.2 154.2 123.2 104.8 135.5 112.3 110.1 189.5 166.2 85.4 181.3 110.1 55.2 100.5 143.8 125.1 79.2 158.6 52.8 38.7 43.5 45.7 47.8 55.7 38.4 38.1 47.6 52.3 32.0 37.8 39.8 31.2 44.6 49.8 31.1 44.8 43.2 19.9 21.8 26.2 25.3 20.1 23.6 24.2 21.8 23.7 23.5 23.0 27.6 55.6 109.0 63.2 29.0 64.3 38.9 59.7 82.6 52.3 28.4 43.0 27.9 31.3 35.8 107.8 44.1 27.1 65.4 71.2 55.9 41.1 77.1 17.2 72.6 81.4 55.5 43.8 50.9 36.9 81.7 69.6 70.5 63.2 72.5 65.2 50.7 51.4 58.1 60.9 18.5 39.1 87.5 61.1 50.7 43.5 10.7 51.0 61.5 21.4 35.6 70.1 34.0 44.3 32.6 49.6 93.6 37.5 55.3 107.4 54.3 60.6 57.3 131.9 29.5 52.6 60.8 78.7 87.5 64.3 48.7 35.8 117.0 77.0 49.3 51.5 60.7 COPS2 "ALIEN, CSN2, TRIP15" ENSG00000166200 "COP9 signalosome subunit 2" P61201 15 49106068-49155661 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016867, HPA018271, HPA061071" Approved Supported "Vesicles,Cytokinetic bridge" Yes No 190000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" Vesicles "Cytokinetic bridge" "HPA016867: AB_1858336, HPA018271: AB_1858335, HPA061071: AB_2684424" "unprognostic (3.47e-1)" "unprognostic (2.28e-2)" "unprognostic (1.66e-1)" "unprognostic (7.20e-2)" "unprognostic (1.86e-1)" "unprognostic (7.84e-3)" "unprognostic (1.04e-1)" "unprognostic (6.77e-2)" "unprognostic (2.49e-2)" "unprognostic (6.09e-2)" "unprognostic (3.86e-3)" "unprognostic (1.42e-1)" "unprognostic (4.35e-3)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (5.62e-2)" "unprognostic (1.10e-3)" 61.7 43.4 24.8 34.4 28.5 124.5 67.0 35.0 36.8 61.9 25.3 43.2 43.3 58.4 44.0 63.2 43.2 53.7 61.5 26.1 30.4 60.8 57.6 35.0 45.5 30.9 27.7 76.7 54.0 65.7 26.4 45.0 32.8 45.2 41.6 32.2 40.0 47.0 92.6 35.5 37.2 56.5 35.2 32.0 36.4 51.0 27.5 49.6 61.8 112.1 48.8 59.0 35.3 41.7 92.0 53.1 111.6 94.4 134.2 189.9 76.7 157.3 149.8 135.4 123.5 113.0 49.1 151.1 105.2 152.2 108.7 131.9 160.3 130.9 148.0 103.3 64.5 141.0 105.4 91.7 102.6 134.7 70.7 161.2 104.3 110.4 193.3 149.3 144.0 82.5 184.4 78.8 149.3 49.5 72.3 67.3 72.6 128.4 68.9 78.2 105.2 227.7 143.5 136.5 108.4 78.6 90.7 96.4 127.8 129.4 95.6 133.3 93.4 132.1 71.0 249.6 167.9 71.0 196.3 191.0 123.4 215.1 109.4 11.7 17.9 12.2 13.1 23.5 24.4 14.6 19.7 19.2 21.0 13.9 24.8 16.2 7.4 16.6 22.9 13.3 28.4 16.0 24.8 28.5 35.0 36.8 26.1 30.4 30.9 27.7 32.8 35.2 27.5 41.7 72.8 76.9 56.1 14.4 50.0 87.1 57.1 90.8 80.8 23.2 47.6 59.3 104.3 27.1 69.8 23.9 10.4 56.1 48.2 18.5 54.8 40.3 28.2 56.7 91.6 53.6 20.8 50.1 35.2 29.9 71.0 79.6 36.2 94.0 52.6 39.3 46.1 32.5 43.9 33.7 36.1 25.1 32.6 47.5 44.9 21.6 55.3 46.1 35.6 19.7 49.3 24.8 27.8 21.6 48.7 35.9 21.6 53.4 63.5 53.0 41.0 84.8 47.4 19.7 19.7 74.6 109.0 93.1 43.3 63.2 98.9 131.9 54.0 58.6 34.6 64.4 COPS5 "CSN5, JAB1, MOV-34, SGN5" ENSG00000121022 "COP9 signalosome subunit 5" Q92905 8 67043079-67083783 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 347.5;Late spermatids: 427.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004242, HPA004845, HPA051531" Supported Enhanced Nucleoplasm NA NA 37000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004242: AB_627835, HPA004845: AB_1078557, HPA051531: AB_2681522" "unprognostic (1.90e-3)" "unprognostic (1.35e-1)" "unprognostic (1.61e-1)" "unprognostic (2.85e-3)" "unprognostic (2.53e-1)" "unprognostic (4.16e-2)" "unprognostic (2.04e-3)" "unprognostic (1.39e-1)" "unprognostic (2.15e-2)" "unprognostic (4.48e-2)" "unprognostic (4.74e-3)" "unprognostic (1.96e-2)" "unprognostic (1.90e-3)" "unprognostic (2.88e-2)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.18e-2)" 43.5 43.8 52.1 33.3 54.2 39.4 45.2 58.3 62.6 34.2 52.0 45.5 45.6 34.0 43.6 42.2 35.6 31.6 100.0 53.2 57.1 56.3 71.0 33.1 40.9 55.1 53.3 33.4 43.0 58.5 31.1 50.9 56.8 36.4 51.6 39.7 42.3 36.6 125.2 36.0 47.8 47.6 57.4 33.4 37.6 58.7 56.2 52.6 37.8 134.9 48.7 42.2 30.0 59.7 104.0 97.8 79.6 74.4 83.1 88.3 63.3 89.0 74.0 121.2 108.9 62.6 125.4 96.5 39.9 93.6 86.8 84.1 109.2 98.9 134.0 92.4 92.1 135.9 95.2 87.3 82.2 86.3 79.1 81.0 126.2 99.1 132.6 95.2 121.2 100.3 163.0 64.6 111.8 96.5 154.3 157.6 107.1 217.2 108.6 97.2 56.7 76.4 131.3 91.6 48.6 66.7 51.0 98.4 91.6 71.2 160.9 90.8 89.9 60.1 74.9 74.7 70.3 81.4 108.5 127.7 89.1 97.6 84.1 65.8 52.0 64.5 35.8 55.7 37.2 36.8 34.6 39.9 63.9 33.7 36.1 32.4 38.3 51.9 56.6 34.0 53.2 43.8 52.1 54.2 58.3 62.6 53.2 57.1 55.1 53.3 56.8 57.4 56.2 59.7 55.0 22.4 26.0 19.2 40.6 49.3 45.1 102.6 28.5 36.4 43.7 51.8 119.9 58.6 61.2 31.3 33.3 143.8 58.0 38.1 88.0 73.4 347.5 44.6 38.2 46.4 34.2 69.2 21.5 60.0 101.4 45.2 25.5 37.1 36.1 50.9 34.2 35.5 79.3 25.2 21.5 41.5 59.0 31.7 28.5 427.2 43.2 40.2 28.4 10.3 59.9 62.0 56.7 18.6 32.4 50.1 48.6 51.1 46.6 54.0 87.8 81.9 46.1 53.0 32.9 49.1 87.8 123.4 49.6 42.9 47.5 127.8 42.3 72.5 55.4 50.6 COPS6 "CSN6, MOV34-34KD" ENSG00000168090 "COP9 signalosome subunit 6" Q7L5N1 7 100088969-100092187 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044315 Approved Supported Nucleoplasm "Intracellular and membrane" NA NA 110000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA044315: AB_10959750" "unprognostic (1.48e-2)" "unprognostic (2.43e-2)" "unprognostic (6.56e-3)" "unprognostic (1.38e-1)" "unprognostic (5.84e-2)" "unprognostic (2.09e-2)" "unprognostic (3.62e-3)" "unprognostic (2.93e-2)" "unprognostic (2.00e-1)" "unprognostic (2.45e-2)" "unprognostic (4.96e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (6.72e-4)" "unprognostic (1.20e-1)" "unprognostic (3.58e-2)" "unprognostic (8.57e-2)" "unprognostic (8.77e-2)" 71.3 85.5 98.5 48.7 103.0 51.8 68.6 102.5 102.0 87.1 99.5 101.3 44.1 86.5 84.0 90.6 78.1 52.9 112.9 101.9 100.7 70.8 71.6 56.5 50.3 99.3 98.4 74.8 60.2 100.8 79.2 64.0 100.4 68.8 57.8 61.4 65.0 74.2 147.3 61.8 58.4 78.5 101.7 63.1 78.4 57.4 98.7 63.1 61.5 152.8 60.6 90.5 74.7 105.0 167.6 233.4 136.2 163.5 116.1 138.4 86.6 147.7 223.5 239.7 174.9 191.9 153.8 114.4 186.1 242.2 267.3 124.1 155.1 247.9 240.4 114.9 242.6 98.2 215.9 149.3 243.3 112.1 97.6 137.5 161.4 259.2 273.9 159.5 333.0 172.7 142.7 160.5 286.4 413.7 251.6 164.8 124.0 241.3 273.2 117.6 226.6 275.4 193.6 153.8 213.4 158.6 152.7 298.5 114.1 176.4 123.7 109.2 177.9 231.3 211.1 280.5 264.8 118.1 140.2 235.3 175.5 150.0 350.6 231.8 187.8 168.2 178.8 206.6 180.7 168.0 176.8 170.9 211.3 170.3 137.4 153.6 73.5 163.5 194.6 157.8 225.8 146.6 98.5 103.0 102.5 102.0 101.9 100.7 99.3 98.4 100.4 101.7 98.7 105.0 87.8 51.3 44.2 24.8 73.4 110.6 118.1 208.1 70.0 108.3 62.8 76.3 166.3 88.6 117.2 86.5 52.1 197.3 84.2 55.1 211.3 138.3 76.5 61.6 103.4 94.9 75.3 69.0 20.9 113.5 133.7 116.0 52.5 48.3 90.7 100.5 90.3 63.2 128.8 95.9 21.0 67.4 158.7 69.6 82.5 197.1 127.7 55.1 156.5 13.1 101.4 147.0 115.4 17.6 24.0 115.1 64.7 125.3 84.3 95.0 84.2 214.2 117.9 127.1 98.6 76.3 261.5 80.5 100.2 81.2 100.3 137.9 82.7 137.9 87.1 96.1 CPSF2 "CPSF100, KIAA1367" ENSG00000165934 "Cleavage and polyadenylation specific factor 2" Q9P2I0 14 92121969-92172145 "Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024238 Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Vesicles "HPA024238: AB_1847200" "unprognostic (2.31e-1)" "unprognostic (9.80e-2)" "unprognostic (3.73e-2)" "unprognostic (1.77e-2)" "unprognostic (4.95e-2)" "unprognostic (2.14e-2)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.34e-1)" "unprognostic (2.94e-1)" "unprognostic (1.78e-2)" "unprognostic (2.33e-2)" "unprognostic (6.68e-2)" "unprognostic (8.78e-3)" "unprognostic (2.44e-1)" "unprognostic (2.91e-1)" "unprognostic (8.75e-2)" "unprognostic (4.90e-2)" 14.8 14.5 7.3 24.9 9.7 11.5 11.8 9.3 10.1 13.7 13.0 16.1 14.7 15.0 15.0 18.3 11.7 15.0 13.1 6.8 8.9 13.6 19.7 14.7 21.0 9.5 9.2 12.6 14.9 18.2 10.7 16.7 10.6 15.6 16.8 13.9 13.6 14.1 27.1 11.1 14.4 17.8 8.5 18.6 17.4 26.0 8.5 27.3 18.3 25.6 24.8 16.6 12.3 12.2 48.1 46.9 47.0 48.6 23.9 21.1 69.5 60.7 59.0 55.1 54.3 41.4 64.9 51.3 38.9 65.1 37.2 69.2 65.2 55.2 79.2 83.3 22.4 75.4 46.1 39.5 70.5 76.3 60.6 34.7 46.2 52.5 93.8 36.5 52.2 54.5 68.8 62.9 62.1 69.6 88.3 26.8 53.3 76.8 42.3 86.0 72.7 45.9 37.5 67.1 51.7 34.7 71.7 39.9 51.1 41.9 82.9 47.4 56.3 43.9 27.7 33.4 52.4 37.6 66.2 103.0 53.0 58.9 69.7 16.6 12.9 9.3 7.8 11.7 10.4 7.6 6.9 8.4 11.3 4.0 6.1 8.6 4.4 11.1 9.8 7.3 12.1 9.5 7.3 9.7 9.3 10.1 6.8 8.9 9.5 9.2 10.6 8.5 8.5 12.2 14.2 28.9 31.8 23.2 22.9 10.3 15.2 15.1 15.9 12.7 13.4 9.5 27.1 10.0 25.5 7.3 29.2 24.0 19.8 14.6 13.7 18.0 28.2 24.3 30.0 22.9 13.8 33.0 13.6 24.0 22.7 20.0 17.3 16.8 30.4 26.2 20.7 27.2 24.8 11.8 17.5 17.3 12.2 32.9 8.8 11.2 19.0 31.1 3.6 19.7 41.2 16.9 27.8 18.6 27.9 23.8 14.0 23.0 35.4 29.9 12.5 16.3 34.1 22.7 32.9 19.6 23.2 61.7 41.3 27.2 12.8 25.3 22.8 26.6 18.2 20.2 CPSF3 "CPSF-73, CPSF73, YSH1" ENSG00000119203 "Cleavage and polyadenylation specific factor 3" Q9UKF6 2 9423651-9473101 "Predicted intracellular proteins" "mRNA processing" "Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 187.6;Spermatocytes: 151.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034657 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA034657: AB_10669728" "unprognostic (9.07e-2)" "unprognostic (2.23e-1)" "unprognostic (2.73e-2)" "unprognostic (1.89e-2)" "unprognostic (2.56e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.30e-1)" "unprognostic (6.82e-2)" "unprognostic (8.45e-3)" "unprognostic (7.39e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (3.93e-5)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (3.64e-1)" "unprognostic (1.10e-2)" 14.2 15.0 10.5 18.4 11.9 23.4 16.9 11.7 13.5 14.5 12.2 17.1 13.9 13.2 23.4 16.2 14.4 11.3 11.1 10.2 11.3 15.6 19.9 12.9 26.3 11.6 10.8 10.4 12.7 14.3 10.6 16.2 12.1 12.7 19.4 11.6 11.5 13.3 15.0 19.2 13.2 16.8 11.4 15.4 13.8 50.9 12.1 32.2 16.4 12.4 30.5 16.4 11.5 13.5 35.7 79.2 85.1 74.4 46.6 54.6 89.2 56.2 60.3 67.2 63.7 100.6 64.5 112.2 51.8 49.3 61.0 61.6 96.0 66.6 81.5 73.9 70.5 95.6 37.7 94.5 40.1 92.8 61.0 49.0 44.6 84.6 61.3 38.2 55.9 71.9 117.0 46.9 64.1 78.7 96.2 121.0 125.9 89.2 54.9 92.6 107.2 94.2 59.9 52.4 46.4 110.7 55.0 41.5 63.5 71.5 40.7 63.1 42.5 53.3 46.1 54.3 70.8 56.1 80.5 118.9 62.3 95.0 57.9 32.9 34.4 23.1 22.2 39.9 23.3 25.3 20.3 23.3 50.1 23.6 20.9 22.6 5.8 38.0 38.4 33.2 36.7 30.5 10.5 11.9 11.7 13.5 10.2 11.3 11.6 10.8 12.1 11.4 12.1 13.5 7.1 6.4 12.7 3.9 15.7 10.5 10.5 26.4 8.6 12.2 7.2 6.5 11.1 8.6 19.5 5.5 8.4 39.5 19.7 9.0 19.6 22.5 187.6 14.6 15.7 11.8 12.6 36.2 9.8 22.5 43.4 13.1 8.6 14.0 8.2 19.9 6.8 14.2 26.1 21.9 9.6 11.9 26.4 20.1 9.5 33.9 11.1 20.6 19.6 10.3 36.3 18.2 16.5 8.5 13.7 16.4 7.4 12.4 15.7 6.5 9.7 18.7 18.0 20.1 6.6 12.3 38.0 151.4 43.2 16.1 8.8 27.2 13.1 26.1 15.1 8.7 CPSF6 "CFIM, CFIM68, CFIM72, HPBRII-4, HPBRII-7" ENSG00000111605 "Cleavage and polyadenylation specific factor 6" Q16630 12 69239569-69274358 "Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039973 Supported Enhanced "Nucleoplasm,Nuclear speckles" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA039973: AB_10795242" "unprognostic (1.50e-1)" "unprognostic (3.33e-2)" "unprognostic (4.37e-3)" "unprognostic (5.47e-2)" "unprognostic (4.24e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (1.91e-6)" "unprognostic (6.82e-2)" "unprognostic (2.91e-3)" "unprognostic (8.57e-2)" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.20e-1)" "unprognostic (7.63e-2)" "unprognostic (2.05e-1)" "unprognostic (7.41e-2)" 23.8 26.3 14.4 35.8 13.9 71.9 23.8 30.5 16.8 27.5 1.8 24.0 26.2 28.4 38.6 27.8 25.3 18.3 21.5 14.5 18.0 20.8 20.6 22.5 46.9 6.1 5.6 40.5 23.9 28.3 26.5 25.0 8.4 23.1 24.8 43.5 26.0 20.2 27.9 24.6 25.4 23.7 8.2 27.1 26.6 22.3 12.6 43.6 26.6 17.0 40.8 25.6 25.2 12.3 97.5 80.3 115.7 81.7 43.8 49.7 87.1 62.7 74.1 87.3 82.0 83.8 64.8 153.6 62.6 63.9 48.5 89.2 114.5 73.7 92.3 101.4 78.1 124.3 85.7 97.1 65.4 170.1 87.1 60.0 57.2 70.4 28.7 58.2 68.3 90.6 130.1 159.6 73.3 112.9 159.9 110.3 112.3 80.4 67.8 159.9 91.6 108.2 68.9 113.4 97.0 85.4 83.7 77.7 88.9 68.8 93.2 118.5 79.1 65.4 80.0 62.6 104.5 101.9 88.5 190.9 53.1 97.5 85.9 44.3 26.0 29.9 27.9 32.6 29.5 32.8 30.8 29.1 39.0 28.9 23.4 28.2 7.7 30.2 28.7 27.8 47.2 19.7 14.4 13.9 30.5 16.8 14.5 18.0 6.1 5.6 8.4 8.2 12.6 12.3 29.1 12.8 24.9 53.2 49.9 76.0 46.7 55.7 43.3 56.5 30.0 24.5 31.7 30.0 39.9 18.4 37.5 64.6 51.1 22.5 37.2 59.6 18.7 35.6 40.2 35.0 52.5 47.1 97.6 56.8 85.7 36.6 33.6 37.9 34.9 54.0 23.6 23.0 39.5 89.2 115.4 32.6 75.3 29.3 39.7 19.8 56.8 37.1 24.9 53.4 53.5 37.8 45.3 137.2 126.0 61.1 23.3 53.0 56.3 37.4 25.4 26.6 28.0 45.8 39.5 37.4 56.0 68.1 69.4 43.9 59.1 51.2 38.5 54.1 36.2 51.5 CRK ENSG00000167193 "CRK proto-oncogene, adaptor protein" P46108 17 1420689-1463162 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010485, HPA068087" Approved Approved "Plasma membrane" NA NA 400000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "CAB010485: AB_2085043, HPA068087: AB_2685950" "unprognostic (6.82e-3)" "unprognostic (1.94e-1)" "unprognostic (8.70e-3)" "unprognostic (5.34e-2)" "unprognostic (2.43e-1)" "unprognostic (3.32e-2)" "unprognostic (2.48e-1)" "unprognostic (1.67e-2)" "unprognostic (6.65e-2)" "unprognostic (1.88e-1)" "unprognostic (2.65e-1)" "unprognostic (5.35e-2)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (3.77e-1)" "unprognostic (1.56e-1)" "unprognostic (3.93e-2)" 48.2 23.2 27.9 20.8 28.3 5.7 30.6 28.1 27.8 26.4 25.2 34.1 26.8 28.2 32.1 26.9 21.0 29.7 27.7 28.2 28.5 31.5 50.1 30.2 17.3 29.6 29.7 24.8 27.3 25.3 11.2 42.2 29.4 23.9 34.4 22.6 23.8 27.0 32.0 20.4 24.2 35.6 30.1 20.4 26.1 20.5 31.2 17.6 36.7 37.9 20.1 31.6 21.8 29.3 45.9 69.8 50.8 54.6 83.7 70.2 47.5 77.3 64.8 59.7 55.3 90.7 26.3 22.0 37.6 89.1 41.7 69.1 68.2 55.8 87.2 11.1 46.6 24.5 43.7 50.2 77.9 10.6 20.9 68.3 64.7 61.9 77.1 45.8 74.3 20.2 42.1 20.3 84.4 46.3 11.5 12.1 46.3 50.4 34.6 24.3 25.7 20.1 78.4 48.4 18.8 49.2 73.5 45.2 54.6 47.7 44.5 17.7 79.8 59.7 33.9 63.8 77.3 9.6 15.8 13.5 50.4 20.6 66.6 6.2 3.9 5.3 3.0 4.2 3.0 3.6 3.2 2.7 4.4 5.2 2.4 3.5 13.9 2.7 4.4 3.9 2.6 1.7 27.9 28.3 28.1 27.8 28.2 28.5 29.6 29.7 29.4 30.1 31.2 29.3 89.5 67.3 51.5 12.7 34.6 149.5 68.8 29.6 50.7 43.8 62.7 45.5 35.2 48.6 33.8 33.1 27.1 63.3 22.1 92.6 41.1 62.1 4.3 55.2 64.5 89.7 49.8 39.5 17.5 65.3 61.6 52.7 47.4 94.1 7.6 33.0 92.8 65.6 45.3 53.8 17.6 61.9 22.4 47.1 91.6 8.3 43.8 46.3 53.4 19.7 45.3 43.5 24.7 12.5 13.6 76.7 60.5 44.0 25.7 77.9 58.3 39.7 32.6 38.9 46.0 59.6 72.9 29.0 58.6 62.8 167.8 85.0 29.9 35.4 66.4 92.2 CSDE1 "D1S155E, UNR" ENSG00000009307 "Cold shock domain containing E1" O75534 1 114716913-114758676 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1408.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 2403.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018846, HPA052221" Supported Enhanced "Plasma membrane,Cytosol" NA NA 100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA018846: AB_1847266, HPA052221: AB_2681767" "unprognostic (2.84e-1)" "unprognostic (9.18e-3)" "unprognostic (4.86e-3)" "unprognostic (3.30e-3)" "unprognostic (2.83e-2)" "unprognostic (4.51e-2)" "unprognostic (5.32e-3)" "unprognostic (5.16e-2)" "unprognostic (1.78e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (2.40e-1)" "unprognostic (4.69e-2)" "unprognostic (4.67e-2)" "unprognostic (1.18e-1)" "unprognostic (5.17e-3)" "unprognostic (2.54e-2)" 412.5 166.8 149.0 170.9 168.8 276.4 241.9 160.5 170.8 193.8 163.5 300.1 187.3 226.7 196.2 247.2 162.9 172.0 414.8 137.6 169.8 228.2 233.6 182.8 172.4 166.4 169.5 258.8 216.2 273.8 85.8 182.4 172.6 229.8 199.6 177.6 230.0 245.6 1408.6 201.6 196.1 236.4 172.2 176.5 201.7 257.4 164.7 218.8 262.6 1039.4 208.2 238.4 137.0 187.3 658.8 226.6 395.5 396.1 440.7 561.4 550.1 566.7 420.5 373.0 301.1 334.0 193.7 514.9 465.6 543.1 217.0 272.3 442.4 439.6 539.2 632.1 302.8 506.1 390.3 299.9 388.2 380.7 288.7 414.7 468.2 447.0 583.2 502.2 433.5 426.5 523.3 327.3 458.9 2403.4 513.8 242.0 755.0 274.0 302.5 378.4 1221.9 244.0 295.4 508.4 485.6 320.7 553.9 455.8 433.3 411.9 234.5 599.4 526.9 437.8 597.3 579.6 629.1 495.7 587.9 567.7 564.9 422.2 1365.1 217.2 241.4 230.8 146.4 233.1 199.7 161.6 186.5 180.7 226.8 130.4 219.3 189.1 155.2 191.0 270.8 87.2 222.2 389.4 149.0 168.8 160.5 170.8 137.6 169.8 166.4 169.5 172.6 172.2 164.7 187.3 193.2 198.7 194.2 41.8 198.3 216.2 219.7 149.0 235.6 134.0 218.2 161.5 572.0 160.2 181.1 128.8 58.4 172.4 155.2 160.8 226.9 198.2 405.5 130.4 178.8 191.3 219.9 232.8 70.8 202.9 208.2 181.7 143.2 174.3 219.1 234.7 156.4 189.1 156.8 99.3 73.7 220.3 120.1 277.9 202.0 639.7 161.8 216.8 220.5 55.3 241.8 195.5 117.4 54.3 86.5 213.8 150.6 225.7 283.6 269.0 240.1 235.5 143.2 121.3 164.3 232.4 274.2 263.3 189.8 247.2 234.0 272.9 193.3 208.2 210.5 283.8 CSNK1A1L MGC33182 ENSG00000180138 "Casein kinase 1 alpha 1 like" Q8N752 13 37103259-37105664 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.5" "Group enriched" "Detected in some" 6 "Early spermatids: 30.0;Late spermatids: 23.0;Spermatocytes: 16.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 39 "granulocytes: 7.6" "Not detected" "Not detected" HPA051334 Uncertain Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA051334: AB_2681446" "unprognostic (1.23e-2)" "unprognostic (1.59e-1)" "unprognostic (3.19e-2)" "unprognostic (3.54e-2)" "unprognostic (2.40e-2)" "unprognostic (5.40e-2)" "unprognostic (8.90e-2)" "unprognostic (3.47e-1)" "unprognostic (1.47e-3)" "unprognostic (4.50e-1)" "unprognostic (2.02e-1)" "unprognostic (2.28e-3)" "unprognostic (3.45e-1)" "unprognostic (2.38e-1)" 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 7.6 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 1.8 3.5 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 30.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 23.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.6 2.2 16.1 1.2 0.0 2.7 0.3 0.0 0.0 0.1 1.7 CSNK2A3 CSNK2A1P ENSG00000254598 "Casein kinase 2 alpha 3" Q8NEV1 11 11351942-11353250 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 12.4;Cholangiocytes: 4.3;Smooth muscle cells: 6.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.1;SK-BR-3: 1.3" "HPA059206, HPA061698" Uncertain Approved Nucleoplasm NA NA "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA059206: AB_2683948, HPA061698: AB_2732667" "unprognostic (3.10e-2)" "unprognostic (3.39e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.82e-2)" "unprognostic (1.60e-1)" "unprognostic (6.25e-4)" "unprognostic (4.36e-2)" "unprognostic (5.42e-2)" "unprognostic (1.88e-1)" "unprognostic (5.46e-3)" "unprognostic (1.07e-1)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.38e-2)" 0.5 0.5 0.7 0.2 0.1 0.0 0.5 0.4 0.6 0.4 0.0 0.5 0.3 0.6 0.0 0.7 0.4 0.0 0.8 0.9 0.0 0.4 0.3 0.6 0.0 0.0 0.0 0.5 0.5 0.0 0.3 0.2 0.0 0.3 0.0 0.1 0.6 0.0 1.8 0.7 0.4 0.2 0.0 0.2 0.5 0.9 0.1 0.0 0.5 0.0 0.0 0.4 0.5 0.0 2.1 0.4 0.1 0.6 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.0 0.3 0.2 0.3 0.2 0.2 0.5 0.3 0.6 0.1 0.9 0.4 0.1 0.3 0.2 0.3 0.1 0.5 0.6 1.3 0.3 0.0 0.4 0.1 0.3 0.3 0.4 0.1 0.2 0.2 0.3 0.3 0.9 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.4 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 3.2 0.5 0.0 0.5 1.8 1.0 0.7 0.0 1.2 0.6 0.9 12.4 4.3 1.0 3.7 0.0 0.7 0.5 0.4 0.0 0.7 2.5 0.1 0.3 2.0 1.2 0.0 0.0 0.8 0.5 0.9 0.0 0.4 1.3 0.6 1.8 0.3 0.3 3.3 0.0 0.3 0.0 1.6 0.8 1.9 0.6 0.2 0.0 0.0 0.6 0.9 1.0 0.0 0.0 0.5 1.2 0.0 0.1 1.2 0.6 0.7 0.9 0.5 0.0 2.3 6.9 0.9 0.9 0.0 1.0 1.0 0.6 1.1 0.6 0.6 CSTF3 CstF-77 ENSG00000176102 "Cleavage stimulation factor subunit 3" Q12996 11 33077188-33162371 "Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039743, HPA040168" Enhanced Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA039743: AB_10795682, HPA040168: AB_10794025" "unprognostic (2.38e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.63e-4)" "unprognostic (3.77e-1)" "unprognostic (4.04e-2)" "unprognostic (4.35e-2)" "prognostic unfavorable (8.20e-6)" "unprognostic (1.47e-1)" "unprognostic (1.67e-2)" "unprognostic (6.42e-3)" "unprognostic (9.73e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (4.64e-2)" "unprognostic (1.86e-2)" "unprognostic (1.15e-2)" "unprognostic (1.01e-3)" 13.8 21.2 28.5 20.8 30.9 12.7 19.5 34.7 39.8 24.2 30.5 20.3 19.1 19.8 61.1 26.7 21.2 14.9 17.1 30.0 32.4 28.9 34.6 21.3 26.6 26.3 26.8 25.9 21.1 18.2 57.6 19.1 27.4 30.4 20.0 31.9 20.6 15.0 16.9 26.1 20.2 13.7 26.1 25.5 18.6 32.9 31.1 23.8 29.8 11.8 21.5 22.0 24.7 32.9 45.8 43.3 82.8 56.4 22.0 38.7 59.8 44.2 28.5 48.5 66.2 31.7 34.9 49.3 31.2 28.5 32.4 58.5 73.8 42.9 77.5 52.7 128.3 50.6 109.1 58.2 24.9 66.5 30.9 28.2 30.6 37.6 36.7 39.1 64.4 39.2 67.9 34.2 66.4 32.3 66.8 35.7 40.3 34.6 54.0 52.2 80.5 39.7 54.6 58.2 61.4 34.9 50.9 29.9 37.6 52.7 54.4 44.1 39.5 40.3 49.7 64.5 59.7 32.3 46.8 41.9 47.4 68.9 40.2 4.6 4.8 7.0 5.8 6.9 6.8 6.5 7.2 5.8 7.7 5.0 7.5 7.9 1.9 6.9 8.3 5.7 9.1 3.7 28.5 30.9 34.7 39.8 30.0 32.4 26.3 26.8 27.4 26.1 31.1 32.9 12.8 19.2 18.7 38.5 19.0 18.9 50.6 50.1 10.2 33.3 22.3 19.9 21.8 17.2 43.5 58.8 6.2 63.0 12.7 15.1 62.6 24.3 37.6 31.4 20.7 21.2 31.8 34.9 75.2 16.9 32.0 23.1 15.3 18.9 14.5 29.0 11.0 57.3 28.4 13.5 59.1 30.0 77.3 22.0 21.1 10.3 29.8 17.0 28.4 42.2 28.1 35.7 14.4 62.4 56.9 20.8 18.6 29.7 14.0 33.0 20.6 47.0 68.0 25.2 26.3 26.1 25.4 77.3 57.6 19.1 19.5 33.8 18.3 25.3 29.6 55.6 CTCF "CFAP108, FAP108" ENSG00000102974 "CCCTC-binding factor" P49711 16 67562467-67639177 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Chromosome partition, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004122, CAB062550, CAB068181, CAB068182" Supported Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB062550: AB_2665624, CAB068181: AB_2665625, CAB068182: AB_2665626, HPA004122: AB_2667139" "unprognostic (2.70e-1)" "unprognostic (4.21e-2)" "unprognostic (3.41e-2)" "unprognostic (4.70e-2)" "unprognostic (4.41e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (4.21e-4)" "unprognostic (1.71e-2)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (1.36e-2)" "unprognostic (1.99e-2)" "prognostic favorable (4.06e-4)" "unprognostic (3.47e-1)" "unprognostic (5.99e-2)" "unprognostic (4.58e-2)" "unprognostic (1.11e-2)" 17.3 14.5 10.6 20.6 12.2 34.6 17.5 17.4 12.7 21.3 7.4 18.9 15.9 20.8 13.8 20.2 19.9 14.6 15.9 10.7 11.9 18.4 18.7 16.4 29.0 10.3 10.2 22.3 18.4 28.3 12.9 20.4 10.3 17.2 21.6 18.4 17.1 17.7 30.5 23.3 19.4 20.3 9.0 22.7 18.3 10.5 10.2 69.6 19.3 28.4 35.4 19.7 20.0 16.2 34.6 51.2 66.9 26.7 29.9 25.5 54.2 32.4 33.6 45.9 43.5 42.3 34.5 106.6 26.0 27.7 26.2 43.8 65.3 35.7 51.5 38.5 44.0 63.9 28.5 49.3 20.4 73.7 59.7 20.8 42.5 34.6 38.2 27.5 35.5 83.1 57.7 43.3 38.6 66.7 156.8 27.4 58.3 38.7 34.5 113.5 54.9 58.7 28.2 48.7 57.0 40.0 57.3 33.2 27.9 35.2 41.0 45.3 33.8 39.3 41.3 30.5 35.7 38.6 52.6 151.2 23.1 43.1 43.1 6.8 2.3 3.4 4.3 2.4 4.1 5.5 4.8 3.5 2.1 7.4 3.8 4.4 6.8 3.5 4.8 5.6 3.9 1.4 10.6 12.2 17.4 12.7 10.7 11.9 10.3 10.2 10.3 9.0 10.2 16.2 38.0 22.4 29.8 19.9 50.4 22.3 24.3 11.4 35.3 35.5 35.6 33.9 32.6 27.1 28.1 23.9 8.4 27.4 54.0 29.2 19.6 31.3 2.1 29.8 43.9 37.3 31.2 52.6 23.0 33.6 33.7 29.9 27.0 40.2 19.6 39.1 23.9 24.0 24.0 45.4 24.2 26.4 16.2 26.7 12.6 3.6 24.8 31.1 12.4 32.8 29.2 32.3 49.4 17.1 32.8 32.5 16.5 28.6 62.6 35.6 18.8 24.5 16.7 27.6 19.7 38.6 41.4 18.4 27.3 38.8 24.7 29.6 47.9 32.6 23.8 30.0 CUEDC2 "C10orf66, MGC2491" ENSG00000107874 "CUE domain containing 2" Q9H467 10 102423245-102432584 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036544, HPA041829" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA036544: AB_10670111, HPA041829: AB_2677694" "unprognostic (2.10e-1)" "unprognostic (2.80e-2)" "unprognostic (7.31e-2)" "unprognostic (4.24e-2)" "unprognostic (9.78e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (1.06e-1)" "unprognostic (4.98e-2)" "unprognostic (1.88e-1)" "unprognostic (2.24e-2)" "unprognostic (1.32e-1)" "unprognostic (3.48e-3)" "unprognostic (4.34e-1)" "unprognostic (1.67e-1)" "unprognostic (8.38e-2)" "unprognostic (1.58e-2)" 45.6 66.6 84.3 28.3 86.0 29.8 42.3 89.4 91.2 49.5 80.5 64.7 19.8 53.4 33.7 30.7 48.3 31.5 91.8 84.4 89.0 55.8 44.9 38.1 33.2 85.1 84.1 56.3 41.0 58.9 45.5 27.8 86.2 48.1 23.3 31.1 40.8 37.3 119.4 37.5 34.2 42.5 83.8 42.8 48.0 38.4 88.1 43.2 42.2 119.2 30.4 48.2 37.7 87.2 53.8 58.2 98.3 120.0 77.3 95.8 35.8 42.4 147.8 95.6 71.6 18.9 56.5 94.4 91.7 76.3 41.7 54.7 65.0 97.3 50.5 75.5 66.4 58.7 50.1 20.8 130.4 45.2 38.0 116.2 89.9 93.6 95.3 187.0 100.1 108.5 46.6 96.5 109.4 58.8 110.2 101.6 35.4 44.1 37.9 124.6 115.0 49.9 101.9 24.8 49.7 113.0 29.6 31.6 96.8 41.5 94.3 71.7 59.5 48.2 45.4 60.6 62.9 112.3 93.2 63.3 84.4 154.2 41.4 98.9 111.5 84.4 69.2 91.5 77.3 80.5 66.9 72.4 112.0 89.5 66.2 63.2 43.0 93.0 58.0 97.9 84.3 86.7 84.3 86.0 89.4 91.2 84.4 89.0 85.1 84.1 86.2 83.8 88.1 87.2 56.6 32.1 21.9 10.7 36.1 31.7 49.0 73.1 44.9 54.7 58.8 81.0 56.8 40.0 37.4 46.0 25.0 66.9 40.6 24.0 80.3 70.0 21.0 28.3 52.9 46.4 55.7 35.7 12.2 46.6 33.2 58.5 31.6 26.6 51.4 89.6 59.3 49.9 75.1 67.3 16.0 36.4 63.1 49.1 47.7 42.2 57.2 44.3 51.6 3.7 97.0 94.7 44.3 13.6 23.4 40.0 32.0 60.2 45.4 38.3 34.5 151.7 28.1 47.5 39.5 46.5 164.9 56.6 31.3 42.6 33.8 45.6 38.7 92.5 39.3 41.9 CUL5 VACM-1 ENSG00000166266 "Cullin 5" Q93034 11 108008898-108107761 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002185, CAB017787" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Cytosol" "CAB017787: , HPA002185: AB_1078587" "unprognostic (5.66e-2)" "unprognostic (6.58e-2)" "unprognostic (7.16e-3)" "unprognostic (1.30e-1)" "unprognostic (5.54e-2)" "unprognostic (1.62e-1)" "unprognostic (2.32e-2)" "unprognostic (2.80e-1)" "unprognostic (5.97e-3)" "unprognostic (1.78e-1)" "unprognostic (9.17e-2)" "unprognostic (1.77e-2)" "prognostic favorable (1.06e-5)" "unprognostic (3.83e-2)" "unprognostic (1.24e-1)" "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" 9.8 11.5 6.8 9.5 7.0 28.3 13.0 10.9 9.1 11.8 7.3 9.1 9.0 13.1 9.9 10.6 9.6 8.5 15.2 6.8 8.0 16.3 14.2 8.8 11.2 6.4 6.8 12.4 8.9 13.4 5.7 11.4 6.5 12.1 9.1 12.7 8.5 9.5 46.4 11.4 8.6 10.5 7.4 9.8 9.4 6.5 6.8 12.7 14.4 37.5 10.3 10.0 7.0 10.3 14.4 6.6 19.6 15.1 12.5 20.2 9.7 15.0 16.3 13.4 15.0 21.3 16.5 20.1 27.3 18.8 14.0 18.0 18.4 12.3 19.4 13.2 11.1 18.9 6.2 15.7 21.1 21.8 14.9 15.8 16.1 14.1 18.6 17.5 18.7 16.2 25.0 7.2 21.4 7.9 20.9 18.1 10.3 18.4 11.6 15.0 14.6 21.8 16.4 21.2 13.9 19.6 20.4 21.1 12.3 12.0 31.1 17.0 19.7 24.6 11.4 17.6 16.2 7.2 6.2 26.5 9.6 24.0 16.0 1.2 2.3 1.6 2.1 2.1 2.0 1.7 2.1 1.9 2.3 2.2 2.3 2.3 0.4 1.6 2.2 2.5 1.7 1.3 6.8 7.0 10.9 9.1 6.8 8.0 6.4 6.8 6.5 7.4 6.8 10.3 50.2 57.7 42.5 66.3 49.0 29.8 29.3 26.0 44.3 52.7 35.1 25.7 111.9 37.1 39.2 31.3 66.7 37.6 49.2 21.8 50.9 29.6 6.0 45.4 48.7 41.3 17.6 34.3 84.9 23.5 23.6 42.6 33.1 40.9 43.1 42.8 40.0 54.8 27.1 55.5 83.8 28.7 22.4 41.6 20.3 8.0 30.7 41.2 14.2 61.8 51.7 31.5 30.9 74.4 101.7 29.1 29.0 38.0 48.4 36.6 27.9 76.7 36.6 59.4 19.7 56.0 53.1 35.5 44.0 43.9 30.3 35.8 38.8 48.0 30.3 32.9 CYFIP1 "KIAA0068, P140SRA-1, SHYC" ENSG00000273749 "Cytoplasmic FMR1 interacting protein 1" Q7L576 15 22867052-22981063 "Predicted intracellular proteins" "Cell shape, Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 253.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 23.5;intermediate monocyte: 24.9;myeloid DC: 22.0;non-classical monocyte: 12.5" "Group enriched" "Detected in many" 5 "dendritic cells: 22.0;monocytes: 24.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068106 Approved NA NA 1100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA068106: AB_2685955" "unprognostic (1.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.85e-1)" "unprognostic (8.20e-3)" "unprognostic (3.94e-1)" "unprognostic (2.09e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.93e-1)" "unprognostic (8.56e-2)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "prognostic favorable (4.47e-5)" "unprognostic (1.20e-1)" "unprognostic (9.36e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-3)" 41.2 26.0 16.6 19.8 16.9 4.7 36.4 15.8 20.0 33.2 16.7 37.7 31.5 33.8 23.8 46.2 24.7 24.0 21.8 15.5 17.9 25.9 26.1 40.5 19.2 20.7 19.5 28.9 41.7 37.3 13.3 39.5 23.1 29.3 28.1 4.4 39.3 24.6 21.2 39.7 29.3 24.9 23.5 26.5 33.8 15.9 21.7 10.2 27.5 14.4 16.2 29.9 36.6 28.6 67.6 74.8 35.5 72.2 42.7 49.3 49.7 47.5 35.7 32.1 31.7 70.0 32.9 0.2 34.1 50.0 32.9 64.2 31.9 58.8 29.7 36.2 45.5 41.3 40.9 51.9 37.3 14.4 29.5 39.3 43.1 25.4 29.7 33.6 48.3 37.0 20.0 23.4 37.8 58.1 1.5 25.7 25.1 87.1 61.8 18.3 45.7 16.6 81.4 114.3 43.1 44.3 40.9 67.2 46.3 35.0 53.1 30.3 49.5 58.7 47.2 24.3 69.6 3.4 7.7 0.7 56.6 32.5 33.7 0.0 23.5 0.4 0.5 24.9 2.4 2.0 2.1 1.0 22.0 0.3 0.4 0.1 0.7 4.3 12.5 3.3 1.6 8.2 16.6 16.9 15.8 20.0 15.5 17.9 20.7 19.5 23.1 23.5 21.7 28.6 56.7 35.3 37.9 18.6 5.7 20.0 27.3 33.8 23.9 2.3 28.9 29.8 7.4 17.2 37.9 18.4 2.1 38.6 4.1 78.7 11.7 33.5 4.5 33.8 35.8 50.7 17.4 9.2 41.8 35.0 40.0 32.2 42.8 50.6 8.8 99.1 35.3 31.5 108.7 5.0 46.1 34.0 28.5 104.5 29.5 5.3 36.4 73.8 28.4 253.9 43.3 17.9 0.0 19.6 16.0 43.2 43.2 32.4 6.3 33.2 41.9 21.8 39.6 2.0 26.3 29.5 40.8 9.0 17.9 40.4 26.3 31.7 4.8 38.5 33.0 34.8 CYTH2 "ARNO, CTS18.1, cytohesin-2, PSCD2, PSCD2L, Sec7p-L, Sec7p-like" ENSG00000105443 "Cytohesin 2" Q99418 19 48469208-48482314 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014872, HPA060662" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Cytosol "Golgi apparatus, Plasma membrane" "CAB014872: , HPA060662: AB_2732652" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.60e-3)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.66e-1)" "unprognostic (2.83e-2)" "unprognostic (3.70e-1)" "unprognostic (1.85e-1)" "unprognostic (2.33e-2)" "unprognostic (9.19e-2)" "unprognostic (3.14e-1)" "unprognostic (1.22e-1)" "unprognostic (1.24e-1)" "prognostic favorable (3.21e-4)" 8.1 12.1 17.2 11.4 17.8 8.1 14.2 20.3 19.0 15.9 15.4 9.3 21.5 10.7 13.6 15.3 7.6 23.2 7.4 16.2 17.1 21.0 7.2 11.2 8.2 18.1 19.1 7.5 16.6 19.6 14.8 16.3 17.4 15.0 8.3 39.0 22.6 9.1 3.6 15.1 21.3 8.2 15.3 10.6 17.5 35.6 21.2 14.9 52.5 5.7 8.8 10.9 10.6 21.2 24.7 36.8 107.9 24.7 16.2 13.9 19.6 18.9 17.3 19.9 18.7 20.1 32.9 16.1 19.2 16.6 16.5 30.4 21.1 23.1 12.5 24.6 28.1 22.5 52.6 22.0 14.6 14.0 29.7 18.0 38.5 24.6 15.9 90.2 26.0 23.4 22.9 55.0 26.6 20.0 23.9 102.5 11.8 22.1 14.9 29.6 15.9 11.2 34.2 52.1 31.9 30.9 20.7 57.6 16.8 34.0 27.1 18.8 28.3 42.6 21.3 10.3 27.8 54.1 30.8 10.8 15.5 27.1 30.7 2.8 2.7 2.3 2.6 2.1 1.8 2.6 3.2 3.7 2.4 1.8 2.8 2.0 7.2 1.4 2.7 3.9 3.6 2.1 17.2 17.8 20.3 19.0 16.2 17.1 18.1 19.1 17.4 15.3 21.2 21.2 48.5 28.9 33.5 15.0 18.7 45.9 115.0 81.1 26.7 35.6 47.6 28.7 11.5 55.8 63.2 40.5 25.0 51.2 42.6 35.0 35.2 82.7 285.9 85.3 26.5 56.0 26.0 4.6 5.7 93.6 47.0 33.5 55.0 56.3 17.7 32.5 50.3 8.3 43.7 21.9 6.8 29.3 67.1 27.9 39.7 163.0 37.3 34.9 35.6 9.4 52.0 42.6 22.6 4.5 12.0 136.6 36.2 36.9 23.2 77.1 57.9 53.3 80.6 59.5 52.6 42.9 70.9 63.5 53.2 23.2 47.5 142.7 33.2 26.0 25.4 139.2 DAZAP1 MGC19907 ENSG00000071626 "DAZ associated protein 1" Q96EP5 19 1407569-1435687 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004201, HPA004631" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 1600000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA004201: AB_1078627, HPA004631: AB_1078626" "unprognostic (1.50e-1)" "unprognostic (3.19e-2)" "unprognostic (7.69e-2)" "unprognostic (2.29e-1)" "unprognostic (7.31e-3)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.86e-4)" "unprognostic (1.83e-1)" "unprognostic (2.30e-1)" "unprognostic (6.13e-2)" "unprognostic (1.09e-1)" "unprognostic (8.11e-3)" "unprognostic (2.72e-3)" "unprognostic (2.40e-3)" "unprognostic (8.30e-2)" "unprognostic (1.65e-1)" "unprognostic (2.21e-3)" 44.2 34.7 20.5 55.9 21.4 69.3 37.2 22.8 23.5 31.9 23.1 45.1 45.3 33.5 10.5 64.7 32.1 13.3 55.0 19.7 20.7 40.6 51.2 37.0 49.8 23.6 21.2 32.3 48.0 20.3 22.6 22.2 22.3 33.0 23.6 20.1 32.4 17.1 65.2 42.3 46.9 19.5 18.2 49.3 39.0 77.5 25.2 47.7 32.1 21.4 34.4 42.2 36.7 27.0 275.7 98.0 64.3 117.9 27.8 33.5 183.9 120.7 59.6 95.7 78.2 98.0 132.3 320.8 72.1 58.7 47.4 151.2 84.9 114.5 80.7 225.9 135.2 165.4 95.2 101.3 64.3 203.1 136.1 33.7 73.8 65.4 119.0 41.1 85.0 133.7 251.5 164.1 60.6 111.9 357.5 178.3 198.7 99.6 97.1 254.3 102.4 199.3 72.9 91.7 127.3 114.2 79.9 124.0 149.3 83.1 113.1 266.8 93.7 79.0 107.5 139.7 267.9 192.9 212.2 256.0 95.6 194.4 123.8 1.5 2.3 1.9 2.7 3.4 2.9 3.1 2.4 2.9 2.2 2.1 2.4 2.6 1.0 3.0 2.4 2.7 2.7 1.3 20.5 21.4 22.8 23.5 19.7 20.7 23.6 21.2 22.3 18.2 25.2 27.0 57.1 9.6 27.6 29.7 50.3 69.3 90.9 37.6 34.1 55.7 46.9 33.3 40.0 38.6 28.8 25.8 35.5 43.5 68.7 60.0 23.5 44.4 49.8 26.3 37.0 45.0 33.0 96.6 17.1 55.1 108.6 39.7 46.9 34.0 26.6 58.0 36.0 41.6 47.7 26.9 16.8 71.6 28.5 49.2 54.9 65.7 28.0 50.3 40.9 16.9 36.0 35.1 34.0 18.6 45.2 63.5 49.4 23.7 73.6 110.3 50.4 48.2 23.5 45.4 26.3 50.5 58.9 111.6 41.0 67.0 74.9 69.0 53.0 41.8 81.5 107.9 DCAF13 "DKFZP564O0463, Gm83, HSPC064, Sof1, WDSOF1" ENSG00000164934 "DDB1 and CUL4 associated factor 13" Q9NV06 8 103414714-103443453 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Ubl conjugation pathway" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044504 Uncertain Supported "Nucleoplasm,Nucleoli,Cell Junctions,Centrosome,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli" "Cell Junctions, Centrosome, Cytosol" "HPA044504: AB_2678963" "prognostic unfavorable (4.06e-4)" "unprognostic (4.39e-2)" "unprognostic (1.70e-1)" "unprognostic (4.46e-3)" "unprognostic (3.57e-2)" "unprognostic (7.86e-3)" "prognostic unfavorable (8.05e-6)" "unprognostic (5.92e-3)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.54e-3)" "unprognostic (2.31e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (6.42e-2)" "unprognostic (8.63e-2)" 16.7 19.2 10.3 22.9 11.0 15.2 23.9 11.3 15.6 17.7 12.8 20.7 16.1 16.2 19.1 21.3 18.0 12.7 16.2 10.9 11.1 32.4 20.7 12.9 24.7 10.8 13.7 13.6 18.5 20.0 15.6 18.7 11.4 14.7 21.4 13.8 14.3 12.8 18.8 15.7 14.5 18.2 11.3 14.3 15.6 32.2 10.4 24.7 18.1 16.0 30.5 33.6 14.6 11.9 96.5 84.2 76.9 79.0 54.7 62.7 57.6 70.1 53.2 64.4 65.9 83.1 90.9 132.2 116.1 73.3 64.0 69.9 105.8 89.0 124.1 127.7 74.9 183.0 48.0 95.9 62.2 76.1 75.7 51.8 59.9 95.9 157.5 40.3 91.4 89.6 125.3 56.7 99.9 78.0 144.9 79.3 118.0 268.9 129.6 92.6 93.3 136.4 95.3 78.6 97.6 92.3 43.5 67.3 83.1 67.4 103.9 51.2 60.6 65.3 105.3 85.5 94.7 61.7 116.5 188.0 88.0 162.8 85.7 19.6 37.6 22.1 35.5 46.5 48.8 60.8 37.5 38.2 54.4 50.8 37.0 38.2 4.2 52.8 35.2 28.3 58.0 44.9 10.3 11.0 11.3 15.6 10.9 11.1 10.8 13.7 11.4 11.3 10.4 11.9 40.0 16.0 17.0 9.1 39.7 79.5 76.6 92.4 38.1 19.6 21.6 24.9 20.8 12.8 53.8 33.1 25.0 57.9 34.8 11.0 39.2 55.0 54.6 26.9 35.4 39.9 14.5 22.1 9.5 48.4 75.0 37.4 17.9 24.7 40.6 49.3 17.5 16.9 42.7 16.8 9.0 17.5 69.2 14.8 23.9 16.7 24.2 22.9 26.6 11.2 28.5 28.8 27.8 16.1 20.0 43.6 12.3 17.7 30.3 51.1 24.3 79.1 36.0 23.7 13.1 50.2 48.0 102.0 86.3 37.1 77.0 33.9 33.1 41.7 28.1 56.9 DCAF8L2 WDR42C ENSG00000189186 "DDB1 and CUL4 associated factor 8 like 2" P0C7V8 X 27590382-27748821 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 34 "testis: 21.4" "Cell type enhanced" "Detected in some" "Smooth muscle cells: 1.3;Spermatogonia: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "U-2 OS: 9.4" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 10: Non-specific - Unknown function" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (5.60e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.7 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 DCTN3 DCTN-22 ENSG00000137100 "Dynactin subunit 3" O75935 9 34613545-34620523 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044905 Approved Approved Nucleoli,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoli "HPA044905: AB_10960996" "unprognostic (3.38e-1)" "unprognostic (4.13e-2)" "unprognostic (3.47e-1)" "unprognostic (6.79e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (2.92e-3)" "unprognostic (9.88e-2)" "unprognostic (4.41e-2)" "prognostic favorable (2.10e-5)" "unprognostic (1.26e-3)" "unprognostic (4.24e-3)" "prognostic favorable (5.76e-11)" "unprognostic (3.06e-1)" "unprognostic (2.25e-1)" "unprognostic (3.22e-1)" "unprognostic (4.43e-2)" 72.9 87.9 98.3 33.7 104.6 107.3 72.2 97.0 123.5 80.6 92.9 81.1 42.0 72.9 46.8 98.5 66.4 38.7 127.1 106.0 103.3 88.6 67.0 60.8 48.0 97.1 97.2 78.7 76.5 94.4 108.4 40.7 102.4 68.2 39.0 57.0 69.2 51.4 152.5 111.1 51.1 53.6 94.1 58.7 75.6 36.3 100.3 81.3 71.5 114.4 59.0 69.5 79.2 95.6 147.1 120.7 110.1 115.6 95.1 132.3 45.1 122.7 112.8 166.4 130.2 77.7 53.8 67.0 74.6 161.8 58.4 57.4 101.0 128.3 105.6 211.9 126.5 44.9 202.9 68.5 102.6 118.8 131.3 117.5 109.4 115.6 75.0 81.4 111.1 123.6 54.2 135.3 147.4 120.9 151.4 320.0 33.4 61.0 192.7 75.2 59.7 93.4 81.5 51.2 36.5 93.3 90.9 82.7 48.0 32.2 110.6 134.5 102.7 104.6 84.1 120.1 121.0 90.6 126.0 45.5 164.1 68.6 217.4 235.2 131.1 187.4 99.9 139.4 92.1 88.4 106.0 106.8 133.8 94.7 83.6 98.9 114.4 102.2 150.3 136.1 179.1 152.5 98.3 104.6 97.0 123.5 106.0 103.3 97.1 97.2 102.4 94.1 100.3 95.6 103.7 32.1 38.3 13.1 61.3 101.6 111.8 180.7 82.0 83.2 97.3 146.9 86.1 77.2 91.8 80.9 25.0 128.8 105.6 74.1 207.4 127.5 14.3 78.6 98.8 79.2 74.7 115.7 16.8 154.6 111.9 97.9 56.6 67.1 87.5 82.4 88.5 84.9 133.8 74.0 16.2 64.9 91.6 88.8 99.0 21.1 103.5 76.8 149.4 5.6 94.9 212.9 125.7 7.5 16.8 126.7 84.5 122.6 89.1 54.7 89.0 240.2 95.0 96.7 59.2 82.0 150.5 82.2 72.9 109.9 142.6 99.7 95.7 143.2 61.6 96.6 DCUN1D5 "FLJ32431, MGC2714" ENSG00000137692 "Defective in cullin neddylation 1 domain containing 5" Q9BTE7 11 103050686-103092194 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050863 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoli Nucleoplasm "HPA050863: AB_2681259" "unprognostic (4.47e-2)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (1.47e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (4.62e-4)" "prognostic unfavorable (2.01e-7)" "unprognostic (1.92e-3)" "unprognostic (1.21e-2)" "prognostic favorable (9.52e-5)" "unprognostic (2.08e-2)" "prognostic unfavorable (4.12e-4)" "unprognostic (2.64e-3)" "unprognostic (1.40e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-2)" "unprognostic (1.43e-3)" 15.8 14.6 11.9 4.2 12.7 4.7 13.2 16.6 17.5 11.3 7.9 11.3 1.4 11.1 3.8 21.4 10.3 1.8 23.9 13.3 12.8 14.3 13.7 11.0 5.1 11.8 13.0 9.1 14.2 3.0 13.0 3.3 12.1 11.3 2.2 7.5 12.2 3.0 31.3 11.8 9.4 2.7 13.2 12.3 13.3 18.5 13.5 4.5 9.2 7.7 4.1 11.9 12.1 13.0 18.2 14.5 18.8 16.3 11.6 13.2 10.0 17.9 6.8 9.0 12.7 51.2 24.8 8.0 32.8 13.3 29.0 21.3 24.3 24.0 16.1 9.7 22.4 21.6 16.2 22.3 18.7 33.7 12.4 7.6 23.8 17.7 22.8 18.3 18.1 32.6 26.3 0.1 10.5 21.6 24.4 46.5 24.5 33.6 32.9 9.5 15.1 22.4 15.4 33.9 12.8 11.0 10.0 21.8 21.4 25.1 20.4 22.4 4.0 12.4 14.8 16.6 17.6 7.8 12.5 33.0 7.9 31.4 13.0 12.8 6.6 6.5 8.7 8.5 10.2 11.3 10.8 9.5 9.5 9.3 9.3 10.3 2.5 15.1 7.1 11.1 11.8 9.3 11.9 12.7 16.6 17.5 13.3 12.8 11.8 13.0 12.1 13.2 13.5 13.0 24.9 16.0 11.0 26.8 30.2 79.5 63.2 101.6 38.1 11.7 34.4 36.2 30.7 15.7 42.8 9.2 8.4 57.2 29.3 8.2 49.0 59.5 5.0 26.5 38.2 27.2 14.4 52.1 50.7 55.6 88.6 35.6 21.9 25.3 15.8 37.3 16.1 25.3 44.7 6.7 39.6 17.9 67.1 29.8 32.4 8.4 14.3 22.7 30.2 15.9 26.5 18.9 15.5 25.6 27.5 63.1 12.2 19.5 52.8 92.6 8.6 39.2 28.0 14.1 26.3 31.5 74.6 121.6 119.8 59.0 83.7 43.8 30.9 59.8 23.2 73.0 DDRGK1 "C20orf116, dJ1187M17.3, UFBP1" ENSG00000198171 "DDRGK domain containing 1" Q96HY6 20 3190350-3204685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013373, HPA013705" Approved Supported "Nucleoli,Endoplasmic reticulum" NA NA 24000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" Nucleoli "HPA013373: AB_2091955, HPA013705: AB_2668872" "unprognostic (2.99e-1)" "unprognostic (1.55e-1)" "unprognostic (3.42e-2)" "unprognostic (1.60e-1)" "unprognostic (6.54e-3)" "unprognostic (2.14e-1)" "unprognostic (1.19e-2)" "unprognostic (1.63e-1)" "unprognostic (4.10e-3)" "unprognostic (8.16e-2)" "unprognostic (5.44e-3)" "unprognostic (7.29e-2)" "prognostic favorable (2.01e-5)" "unprognostic (6.80e-3)" "unprognostic (1.43e-2)" "unprognostic (2.48e-2)" "unprognostic (6.90e-2)" 44.6 89.1 43.2 23.8 44.6 24.8 45.5 38.9 65.7 50.8 36.7 43.3 43.4 43.5 20.0 46.0 49.0 22.4 38.4 42.3 36.8 51.2 77.9 51.6 23.6 39.7 38.8 48.9 84.1 54.7 36.6 25.9 39.5 45.7 19.2 43.2 61.7 32.2 58.2 53.0 44.9 19.9 33.5 36.3 63.0 34.8 37.5 18.6 51.3 14.1 17.0 43.5 44.6 48.4 108.5 133.3 32.3 60.6 71.7 27.2 46.6 67.2 31.9 40.6 44.1 105.7 76.7 64.3 53.6 37.5 77.9 118.2 33.5 100.6 14.8 44.0 62.8 54.4 45.6 186.1 97.9 62.1 56.6 42.8 96.2 77.8 55.2 44.8 37.5 45.3 77.0 74.8 26.4 59.2 42.9 115.5 40.1 73.6 60.8 55.9 28.7 98.6 66.7 99.8 71.4 44.1 69.2 192.7 65.6 19.2 82.0 37.6 57.2 64.9 28.8 46.3 104.2 55.8 67.7 27.3 18.0 51.6 38.9 23.1 36.9 45.6 33.3 25.3 32.7 26.9 35.0 35.6 36.8 26.3 30.8 30.5 9.5 24.6 23.2 57.3 36.2 25.9 43.2 44.6 38.9 65.7 42.3 36.8 39.7 38.8 39.5 33.5 37.5 48.4 57.3 44.8 53.9 19.9 35.1 26.3 68.8 119.0 44.3 47.9 77.1 72.3 31.3 91.5 114.3 69.9 64.6 127.5 50.9 105.8 19.6 147.0 42.2 54.8 42.6 54.1 53.4 26.5 28.6 178.8 65.1 49.3 54.0 79.0 27.3 34.8 50.0 125.6 119.3 52.2 13.9 72.2 154.6 60.9 36.0 21.1 55.9 54.2 39.2 7.5 67.8 73.7 64.9 6.0 28.4 145.0 125.3 68.8 60.5 75.7 216.3 80.5 81.6 108.3 65.7 39.1 115.6 38.7 23.6 64.0 38.8 146.0 44.7 70.0 92.7 75.0 DDX41 "ABS, MGC8828" ENSG00000183258 "DEAD-box helicase 41" Q9UJV9 5 177511577-177516961 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017911, HPA048803" Supported Supported Nucleoplasm,Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA017911: AB_1847558, HPA048803: AB_2680527" "unprognostic (2.52e-1)" "unprognostic (1.51e-1)" "unprognostic (7.57e-2)" "unprognostic (1.02e-1)" "unprognostic (2.34e-1)" "unprognostic (2.61e-2)" "unprognostic (4.21e-3)" "unprognostic (2.60e-2)" "unprognostic (1.92e-1)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (4.47e-2)" "prognostic unfavorable (2.21e-6)" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (1.75e-1)" 26.5 29.0 15.1 28.7 16.1 22.3 25.4 13.1 21.9 26.1 13.7 26.5 24.8 25.2 16.8 33.7 30.6 18.3 18.9 17.8 14.2 26.8 27.1 24.5 24.7 15.8 13.7 28.6 23.5 31.2 18.0 22.8 16.0 22.3 19.3 14.6 28.7 19.1 43.4 35.0 28.7 20.1 12.8 26.7 26.7 17.9 16.2 24.3 29.0 20.3 25.0 24.8 27.6 16.4 62.1 71.4 42.4 44.9 43.4 45.2 125.1 58.4 35.1 47.1 36.1 107.7 61.3 67.2 83.3 57.6 67.6 47.8 57.2 128.5 33.2 175.4 68.0 90.5 70.8 66.5 52.5 89.3 82.3 48.7 47.0 45.3 59.0 43.5 53.4 68.1 72.3 50.0 55.6 135.5 80.6 45.9 62.0 59.0 61.3 72.7 48.1 86.2 50.5 78.8 45.0 41.9 64.6 83.2 56.5 27.1 54.6 110.2 51.3 74.4 42.8 43.6 87.6 49.6 75.9 120.1 81.3 100.1 47.0 14.3 31.4 22.3 18.3 28.5 23.5 17.0 18.3 16.8 27.2 14.4 14.6 18.8 9.2 25.8 31.4 11.2 18.8 25.6 15.1 16.1 13.1 21.9 17.8 14.2 15.8 13.7 16.0 12.8 16.2 16.4 17.0 25.6 17.8 7.8 20.6 21.0 22.9 37.9 18.2 16.9 17.5 16.5 9.0 25.8 24.3 9.2 2.1 46.6 22.9 22.9 41.1 42.1 11.2 16.1 16.5 22.3 11.4 25.2 6.0 39.6 63.2 17.6 17.3 19.2 29.8 21.3 16.1 18.0 48.8 8.4 6.4 27.0 18.3 23.5 15.4 22.9 14.9 22.2 12.4 4.7 34.6 23.9 20.6 5.0 3.9 33.5 23.9 21.1 23.2 19.0 29.5 40.1 20.5 10.3 13.1 14.5 29.0 24.5 26.7 26.2 20.3 37.5 19.0 25.6 31.0 22.7 DDX42 "RHELP, RNAHP, SF3b125, SF3B8" ENSG00000198231 "DEAD-box helicase 42" Q86XP3 17 63773603-63819317 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023447, HPA023571, HPA025941" Approved Enhanced "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA023447: AB_1847560, HPA023571: AB_1847561, HPA025941: AB_1847562" "unprognostic (3.46e-1)" "unprognostic (7.11e-2)" "unprognostic (8.44e-2)" "unprognostic (1.29e-1)" "unprognostic (2.49e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.06e-1)" "unprognostic (4.73e-2)" "unprognostic (1.90e-1)" "unprognostic (2.54e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (9.26e-4)" "unprognostic (3.02e-1)" "unprognostic (2.42e-1)" "unprognostic (7.35e-2)" "unprognostic (1.55e-2)" 43.5 32.6 27.4 30.5 29.4 37.3 42.7 26.2 29.7 38.5 21.6 42.9 31.3 42.4 39.0 32.6 44.0 30.2 35.3 25.8 30.8 30.0 34.8 35.8 40.6 29.9 30.1 54.7 54.4 39.9 29.2 36.5 28.9 39.3 36.4 39.3 47.3 40.7 59.2 39.6 33.5 43.1 29.0 37.2 37.1 39.8 30.7 40.1 34.2 42.7 47.1 39.5 30.6 26.5 87.4 89.9 79.2 81.3 78.2 62.7 85.0 83.4 74.6 74.7 72.9 84.7 55.9 120.8 32.0 94.3 62.4 68.2 90.3 74.3 98.5 35.9 59.1 91.0 92.0 104.2 77.1 106.9 59.7 80.3 69.2 67.9 81.6 63.5 75.2 61.6 103.2 49.7 77.0 71.3 102.8 59.3 75.8 69.4 47.4 88.7 135.8 62.3 68.2 101.3 49.5 93.9 63.2 112.3 74.1 110.7 77.2 87.1 80.5 109.9 67.0 45.3 99.4 55.6 47.9 109.5 56.4 58.1 58.9 1.9 2.2 6.9 3.7 2.2 4.2 2.8 3.0 3.7 2.9 5.3 3.6 3.7 2.0 4.5 4.3 1.8 2.1 1.9 27.4 29.4 26.2 29.7 25.8 30.8 29.9 30.1 28.9 29.0 30.7 26.5 41.5 80.1 60.4 24.2 34.7 31.2 24.4 24.5 48.9 40.9 37.0 38.0 49.5 30.0 49.0 36.8 37.5 33.3 29.3 27.0 13.7 30.4 9.2 64.9 68.0 41.8 40.7 33.0 33.6 27.1 24.4 42.2 32.1 72.0 30.4 82.1 30.0 34.5 23.2 50.5 30.3 37.8 28.5 32.7 26.1 12.7 48.7 29.6 14.2 21.5 55.5 46.6 32.0 18.1 26.7 41.1 25.3 50.4 36.7 39.0 26.5 23.5 65.5 46.7 39.5 63.2 51.8 68.5 63.1 52.7 29.7 27.4 32.7 71.3 33.8 32.4 DDX50 "GU2, GUB, MGC3199, RH-II/GuB" ENSG00000107625 "DExD-box helicase 50" Q9BQ39 10 68901286-68946847 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037388, HPA037389, HPA058196" Approved Enhanced Nucleoli NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoli "HPA037388: AB_10671752, HPA037389: AB_2675450, HPA058196: AB_2683635" "unprognostic (2.05e-1)" "unprognostic (3.36e-1)" "unprognostic (9.90e-2)" "unprognostic (9.75e-2)" "unprognostic (1.29e-1)" "unprognostic (1.23e-1)" "unprognostic (1.47e-3)" "unprognostic (2.62e-1)" "unprognostic (1.97e-1)" "unprognostic (8.78e-2)" "unprognostic (4.57e-2)" "unprognostic (1.44e-1)" "unprognostic (4.22e-3)" "unprognostic (1.22e-2)" "unprognostic (2.38e-2)" "unprognostic (4.91e-2)" "unprognostic (1.02e-1)" 21.5 16.9 12.3 19.0 12.4 17.3 25.5 14.6 13.9 24.5 14.2 25.1 13.1 27.3 18.1 19.9 22.5 17.4 18.6 12.5 13.5 19.1 16.3 15.9 27.7 12.1 12.2 30.4 20.9 23.1 21.9 22.1 12.3 19.7 17.9 23.3 15.8 22.5 20.9 17.7 16.3 27.3 12.5 19.7 17.5 25.8 13.3 30.6 25.7 20.7 27.4 23.7 20.0 14.0 48.3 30.6 53.8 67.0 45.4 58.6 33.5 50.2 56.7 45.7 42.5 69.3 41.3 62.4 29.4 45.7 27.9 41.5 53.4 38.0 58.0 54.6 38.5 33.6 30.0 31.0 45.6 71.7 40.5 45.9 38.2 43.7 120.7 79.3 37.3 52.8 60.8 37.5 57.0 39.7 67.6 67.7 31.3 46.7 67.3 58.0 60.6 11.4 35.5 28.7 36.9 50.2 36.5 43.0 57.1 50.2 50.6 45.3 32.0 35.1 40.0 39.5 69.5 49.7 47.6 52.8 37.6 72.8 20.9 9.2 10.6 15.0 18.5 16.7 22.9 16.8 22.8 19.4 14.0 17.1 24.1 21.9 3.4 20.6 13.6 12.4 21.8 15.0 12.3 12.4 14.6 13.9 12.5 13.5 12.1 12.2 12.3 12.5 13.3 14.0 27.8 19.2 21.7 21.2 50.5 11.9 35.4 34.6 36.5 44.2 21.1 23.1 27.4 30.0 31.5 20.2 39.6 40.6 36.0 11.4 56.7 28.7 80.3 25.2 41.6 30.3 16.2 29.5 37.5 25.1 39.3 32.2 22.4 22.8 43.0 30.3 23.2 16.2 23.2 37.0 36.4 19.2 26.4 21.6 9.1 20.0 36.4 21.3 12.4 22.5 41.2 22.7 51.5 28.1 29.5 22.8 14.3 39.1 46.3 30.1 11.1 41.3 26.7 55.1 19.7 35.8 53.5 72.8 58.4 31.7 14.3 41.2 40.8 35.4 21.4 20.7 DENR "DRP, DRP1, SMAP-3" ENSG00000139726 "Density regulated re-initiation and release factor" O43583 12 122752824-122771064 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 227.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021783 Approved Approved Cytosol NA NA 200000 "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA021783: AB_2670820" "unprognostic (3.65e-2)" "unprognostic (7.00e-2)" "unprognostic (5.69e-2)" "unprognostic (7.33e-3)" "unprognostic (6.62e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (1.58e-7)" "unprognostic (2.23e-3)" "unprognostic (2.13e-2)" "unprognostic (2.11e-2)" "unprognostic (3.75e-1)" "unprognostic (1.02e-3)" "prognostic unfavorable (8.57e-6)" "unprognostic (1.32e-1)" "unprognostic (1.26e-1)" "unprognostic (2.65e-1)" "unprognostic (1.35e-1)" 25.4 22.6 19.0 27.0 19.6 27.5 29.6 15.3 23.6 22.2 15.1 25.5 26.7 23.7 22.1 32.5 21.7 22.1 24.4 19.4 20.2 25.5 27.6 18.8 36.2 16.8 21.6 19.2 21.2 59.0 17.1 31.6 19.5 28.0 26.0 16.5 28.4 24.8 60.2 29.6 25.0 24.5 15.2 28.0 23.3 14.6 18.9 38.9 29.8 44.7 35.5 30.0 20.4 16.7 113.1 62.1 77.7 80.1 48.7 71.9 67.6 100.5 56.1 87.6 60.6 86.9 40.6 99.9 103.4 72.5 66.6 84.0 93.8 89.5 117.6 90.9 67.3 122.8 36.2 63.8 63.5 139.6 97.4 62.8 86.9 79.3 107.4 81.6 86.4 109.7 129.8 35.8 94.8 74.9 137.7 134.1 159.2 67.2 128.4 120.6 91.2 63.7 85.3 99.9 89.3 63.4 139.2 40.8 107.3 79.1 129.5 78.1 82.2 81.2 95.9 91.7 102.1 58.8 145.8 160.4 76.4 100.1 90.9 227.9 35.0 58.1 38.8 53.3 45.3 45.5 41.9 39.4 47.3 41.4 48.5 43.4 42.2 47.3 69.9 42.1 49.2 44.5 19.0 19.6 15.3 23.6 19.4 20.2 16.8 21.6 19.5 15.2 18.9 16.7 43.4 70.5 40.1 31.0 59.8 71.9 65.9 55.4 59.7 37.7 66.2 69.8 66.3 45.8 47.7 47.8 41.7 73.0 60.8 40.9 64.6 68.6 17.9 67.7 83.5 51.4 84.8 53.8 39.0 61.8 130.3 48.3 40.8 70.7 43.1 50.4 42.1 54.3 57.4 55.5 36.2 53.6 44.7 50.1 42.4 8.0 50.4 49.3 26.6 25.3 60.2 47.3 75.2 48.2 31.3 88.0 44.6 45.9 47.9 73.2 40.3 67.3 49.5 35.9 19.7 46.2 62.5 120.3 136.8 72.8 64.9 60.6 54.7 47.3 58.8 51.3 DHX15 "DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p" ENSG00000109606 "DEAH-box helicase 15" O43143 4 24517441-24584554 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047047 Approved Enhanced "Nuclear speckles" NA NA 130000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA047047: AB_2679916" "unprognostic (4.46e-3)" "unprognostic (2.47e-2)" "prognostic favorable (5.74e-4)" "unprognostic (3.35e-1)" "unprognostic (5.30e-2)" "unprognostic (5.74e-2)" "unprognostic (2.06e-3)" "unprognostic (5.53e-3)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (3.60e-2)" "unprognostic (8.68e-3)" "unprognostic (7.77e-3)" "unprognostic (2.51e-3)" "unprognostic (2.19e-1)" "unprognostic (1.59e-1)" "unprognostic (5.41e-3)" 40.3 35.7 17.0 51.2 23.2 78.5 50.7 30.5 22.6 41.3 29.4 48.8 36.8 44.5 30.2 43.9 38.5 35.6 33.3 18.4 20.9 45.7 44.7 37.1 60.2 20.9 20.3 43.8 47.7 52.1 21.6 55.0 22.0 39.5 57.9 40.1 37.7 35.9 43.0 42.1 37.9 48.0 20.8 40.0 44.7 33.5 20.2 79.8 40.0 42.2 70.9 65.6 34.7 29.0 135.0 129.1 209.4 104.6 100.6 97.4 124.7 153.0 133.9 157.8 155.5 132.0 158.5 245.4 91.8 126.2 183.7 109.8 272.1 184.1 243.7 90.6 129.0 213.3 134.7 107.3 59.2 222.3 140.9 82.2 108.4 154.3 103.1 100.8 133.9 113.4 203.4 96.2 181.3 101.3 293.7 148.2 228.4 133.4 115.8 190.4 245.3 114.6 187.1 190.2 179.0 111.9 118.7 112.8 109.1 149.0 123.8 113.7 123.5 132.8 87.5 101.6 181.4 72.1 130.2 289.3 89.1 177.9 161.8 57.5 29.6 28.5 28.8 30.8 39.7 28.7 32.0 33.7 39.0 29.9 33.2 32.2 13.9 37.1 38.5 25.8 38.6 28.5 17.0 23.2 30.5 22.6 18.4 20.9 20.9 20.3 22.0 20.8 20.2 29.0 51.2 76.9 57.4 40.1 53.4 98.7 68.3 58.0 56.3 30.2 50.1 36.7 28.1 35.8 70.6 27.6 22.9 72.7 44.9 79.8 37.2 59.3 32.6 61.7 53.2 53.6 60.5 58.9 51.4 41.8 69.7 55.5 79.5 97.3 57.0 47.4 42.8 48.4 44.7 26.9 50.8 69.3 36.7 46.9 53.2 16.5 39.4 50.2 48.0 49.6 48.0 24.4 34.0 61.3 99.1 57.1 41.2 40.3 51.0 73.1 33.2 34.8 55.6 32.1 26.3 59.6 69.4 72.9 46.3 60.4 100.0 88.2 49.3 34.0 71.2 89.4 DLGAP4 "DAP4, KIAA0964, SAPAP4" ENSG00000080845 "DLG associated protein 4" Q9Y2H0 20 36306336-36528637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 213.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054105, HPA056378" Approved Approved "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA054105: AB_2682381, HPA056378: " "unprognostic (1.11e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-2)" "prognostic unfavorable (2.24e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.73e-6)" "unprognostic (1.23e-1)" "prognostic favorable (9.88e-5)" "unprognostic (1.28e-1)" "unprognostic (2.18e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.07e-1)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" 55.4 47.5 39.0 23.5 31.4 7.5 40.3 2.8 45.9 51.7 2.6 71.4 21.2 64.5 12.5 31.7 45.2 26.4 58.4 39.3 12.3 34.3 37.3 60.5 16.6 5.4 18.1 48.4 47.8 13.8 36.4 26.5 10.5 44.7 15.0 25.4 37.8 30.6 130.8 86.8 37.1 42.5 2.8 32.9 36.5 29.3 29.1 14.7 43.3 45.9 14.8 56.2 46.6 20.6 49.9 44.2 53.0 44.1 49.0 79.9 53.2 73.2 66.5 70.0 48.2 67.4 30.9 14.0 38.5 103.3 61.9 46.7 14.3 75.1 51.8 22.5 5.2 31.8 22.7 46.2 70.9 12.9 26.5 52.9 57.0 83.1 57.6 54.2 69.7 19.5 22.5 37.2 53.6 37.0 26.3 49.0 23.2 36.2 93.4 26.1 14.0 19.4 33.0 24.3 34.8 47.9 48.0 96.0 60.0 53.7 55.3 22.3 71.2 212.1 64.6 92.6 40.9 12.7 9.8 15.1 84.9 16.2 85.4 2.7 16.5 26.9 15.0 17.3 11.9 19.5 13.5 10.7 14.5 20.8 10.1 8.1 23.6 9.6 17.9 17.4 11.9 12.6 39.0 31.4 2.8 45.9 39.3 12.3 5.4 18.1 10.5 2.8 29.1 20.6 30.4 16.0 20.5 34.0 25.2 66.4 53.8 30.6 9.1 34.9 30.2 21.0 27.9 22.8 22.9 12.9 8.4 23.1 23.7 27.2 7.9 53.0 69.9 25.9 47.7 36.6 63.3 4.4 77.9 55.7 52.3 40.1 23.4 29.4 12.6 35.7 27.8 17.5 27.2 74.0 93.4 35.0 20.3 22.4 54.4 213.4 29.8 23.9 10.6 37.5 47.5 38.7 21.6 81.4 13.2 84.4 25.0 26.4 8.9 72.9 25.8 20.4 28.3 29.5 72.3 28.8 51.0 13.7 30.3 13.2 71.7 55.1 20.7 29.8 20.6 52.3 DNAJA2 "CPR3, DNAJ, DNJ3, HIRIP4" ENSG00000069345 "DnaJ heat shock protein family (Hsp40) member A2" O60884 16 46955362-46973674 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049789, HPA060538" Approved Approved "Nucleoli,Intermediate filaments,Cytosol" NA NA 67000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Cytosol" "Intermediate filaments" "HPA049789: AB_2680883, HPA060538: AB_2684315" "unprognostic (7.68e-3)" "unprognostic (1.05e-2)" "unprognostic (4.77e-2)" "unprognostic (3.67e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (2.81e-4)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.53e-2)" "unprognostic (5.41e-2)" "unprognostic (2.12e-1)" "prognostic favorable (1.19e-9)" "unprognostic (9.22e-2)" "unprognostic (2.28e-1)" "unprognostic (9.22e-2)" "unprognostic (4.69e-2)" 20.7 25.2 30.5 14.2 32.6 23.9 19.7 33.9 40.5 17.9 32.2 21.3 20.0 22.0 28.6 21.5 17.4 16.4 36.0 32.3 31.9 28.0 36.0 16.6 19.7 29.8 30.2 22.0 17.0 29.2 16.4 19.9 30.5 21.8 19.0 29.5 17.1 20.6 37.1 21.1 20.5 17.0 31.0 22.7 19.2 24.9 31.2 20.3 22.2 38.7 21.4 21.6 18.2 30.5 23.1 26.9 26.6 22.8 35.7 34.1 40.3 29.4 35.4 43.4 20.5 23.7 23.6 37.1 23.2 31.9 18.6 35.0 43.0 30.2 49.8 8.8 36.0 27.2 12.8 50.7 42.7 41.7 36.3 36.5 34.6 25.2 23.7 37.9 30.4 14.7 31.7 12.0 37.0 25.4 30.1 57.5 40.6 21.1 39.6 34.3 48.7 44.1 52.7 24.1 36.1 23.1 34.9 52.1 33.4 26.1 20.3 32.2 31.6 25.4 16.0 18.5 25.1 29.3 21.7 49.0 26.9 35.5 21.8 13.1 10.3 13.5 9.8 12.7 12.9 11.3 13.2 11.2 9.4 8.4 12.9 13.1 10.7 12.8 11.3 6.7 17.2 9.7 30.5 32.6 33.9 40.5 32.3 31.9 29.8 30.2 30.5 31.0 31.2 30.5 64.3 51.3 35.9 11.8 78.4 126.9 75.1 56.4 101.3 38.8 37.5 28.4 100.3 40.0 48.2 40.5 18.8 85.2 76.1 67.6 90.1 73.4 93.3 86.9 76.8 52.2 52.0 49.4 16.6 62.2 72.5 66.2 54.0 72.1 53.9 52.7 31.1 54.9 56.5 37.0 15.3 55.6 52.9 42.5 86.4 56.8 50.1 65.1 72.9 12.2 72.3 60.5 45.3 10.1 11.0 71.2 64.2 59.0 70.7 61.6 83.3 111.4 67.6 43.7 52.6 63.4 99.4 177.7 106.0 111.1 120.5 172.4 89.6 131.4 62.6 87.3 DNAJC13 "KIAA0678, RME8" ENSG00000138246 "DnaJ heat shock protein family (Hsp40) member C13" O75165 3 132417502-132539032 "Human disease related genes, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036923, HPA036924" Approved Supported Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" Vesicles Cytosol "HPA036923: AB_10672480, HPA036924: AB_2675386" "unprognostic (3.35e-3)" "unprognostic (7.47e-2)" "unprognostic (9.16e-2)" "unprognostic (1.20e-2)" "unprognostic (9.71e-2)" "unprognostic (4.92e-2)" "prognostic unfavorable (7.49e-4)" "unprognostic (3.68e-2)" "unprognostic (3.38e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (8.36e-4)" "unprognostic (1.92e-1)" "unprognostic (4.81e-3)" "unprognostic (2.15e-1)" "unprognostic (1.71e-1)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" 11.7 9.4 5.9 12.4 6.5 15.5 11.4 6.0 6.3 12.9 8.2 14.4 10.9 13.8 11.7 10.7 9.9 9.9 12.9 5.9 6.9 16.0 9.8 11.3 11.0 7.7 6.9 11.7 6.8 12.6 5.9 15.4 7.1 10.8 14.3 10.7 9.1 12.1 12.5 9.8 10.4 16.7 6.3 12.2 9.7 7.8 7.5 12.0 15.7 14.2 10.6 12.4 10.3 7.8 31.0 18.0 22.2 10.9 54.3 46.7 13.7 32.3 62.5 31.4 33.8 20.4 18.2 15.7 20.5 46.3 41.1 24.1 22.1 24.3 43.5 18.3 6.4 20.6 17.1 13.6 27.6 21.1 18.3 34.2 16.4 28.5 35.1 22.7 44.6 26.0 11.4 25.6 43.7 24.1 16.8 9.1 12.7 26.7 15.8 15.9 16.5 13.0 27.7 32.4 7.9 11.9 31.6 16.7 36.1 19.0 24.7 17.8 40.9 34.7 17.8 33.3 13.9 14.8 15.7 21.5 36.8 13.6 25.2 2.0 2.6 0.4 0.8 2.2 0.7 1.0 0.9 0.7 2.8 0.4 0.6 0.8 0.5 0.7 4.0 1.4 0.4 0.8 5.9 6.5 6.0 6.3 5.9 6.9 7.7 6.9 7.1 6.3 7.5 7.8 16.8 12.8 21.9 45.7 14.4 6.6 7.3 7.3 6.8 10.8 8.9 7.2 47.2 8.6 11.3 12.9 33.3 7.9 13.2 21.5 1.9 9.0 1.7 10.3 31.3 17.1 14.4 12.8 48.7 9.1 7.7 20.2 16.8 18.7 12.0 18.9 13.2 8.5 20.5 67.3 48.7 12.5 0.0 34.2 9.2 3.6 15.2 26.5 28.4 60.0 25.1 13.3 6.2 46.8 64.7 11.7 12.5 21.4 13.9 10.5 17.0 18.7 13.1 11.5 6.6 22.3 19.7 5.3 13.7 15.4 7.5 5.1 10.8 22.5 13.4 11.0 DNAJC14 "DNAJ, DRIP78, FLJ32792, HDJ3, LIP6" ENSG00000135392 "DnaJ heat shock protein family (Hsp40) member C14" Q6Y2X3 12 55820960-55830824 "Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017653 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" "HPA017653: AB_1847799" "unprognostic (2.54e-2)" "unprognostic (1.77e-2)" "unprognostic (1.47e-1)" "unprognostic (1.90e-1)" "unprognostic (6.04e-2)" "unprognostic (3.14e-2)" "unprognostic (6.91e-3)" "unprognostic (6.92e-2)" "unprognostic (3.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.63e-1)" "unprognostic (4.34e-2)" "unprognostic (3.89e-3)" "unprognostic (4.73e-2)" "unprognostic (7.98e-2)" "unprognostic (9.17e-2)" "unprognostic (8.92e-2)" 14.0 13.2 14.2 15.4 14.8 16.3 15.6 13.4 14.2 16.0 14.2 14.2 13.8 15.4 16.9 11.3 17.4 12.6 12.2 14.0 13.3 16.4 16.9 15.2 16.9 14.5 14.6 12.8 13.5 24.6 11.5 16.2 13.8 14.8 15.0 12.3 15.5 13.4 11.2 13.2 15.0 16.1 13.8 17.6 14.6 18.6 14.6 23.6 17.7 11.3 19.0 14.2 10.4 16.2 25.0 29.7 31.9 32.3 31.3 29.5 36.1 27.6 35.8 35.2 25.5 24.2 41.5 31.5 51.9 31.4 24.3 26.9 28.7 34.4 32.1 50.8 20.6 43.6 28.0 20.4 32.4 26.5 35.9 26.5 28.3 35.4 32.8 52.4 38.7 45.7 34.0 36.4 40.6 29.5 48.8 26.3 25.1 24.8 24.8 39.6 28.5 27.6 32.4 21.3 43.1 40.2 22.2 30.5 21.0 30.6 64.1 40.1 33.6 33.2 30.6 31.2 22.6 43.7 40.7 27.7 33.7 24.1 42.1 14.8 9.5 16.1 12.9 8.4 10.2 10.3 9.6 11.6 9.1 7.4 8.4 10.5 7.8 11.3 11.5 11.6 8.4 11.1 14.2 14.8 13.4 14.2 14.0 13.3 14.5 14.6 13.8 13.8 14.6 16.2 9.2 6.4 7.7 1.6 6.8 4.0 4.0 8.1 5.7 7.1 7.5 4.2 0.8 7.2 9.0 11.0 10.4 10.0 6.7 9.6 3.9 9.8 4.5 7.1 7.7 8.1 7.2 10.8 3.9 7.7 14.1 6.4 7.7 6.8 1.3 9.7 5.3 7.4 9.8 1.7 3.8 5.2 0.0 12.5 10.7 4.7 9.6 9.2 7.2 3.7 8.6 7.9 13.4 1.5 5.5 9.3 7.7 9.1 8.5 5.6 8.0 7.5 6.9 5.2 6.6 7.4 11.5 6.8 10.0 5.1 4.1 13.0 6.3 7.7 7.2 3.5 DNAJC2 "MPHOSPH11, MPP11, ZRF1, ZUO1, zuotin" ENSG00000105821 "DnaJ heat shock protein family (Hsp40) member C2" Q99543 7 103312289-103344830 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chaperone, Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 248.5;Spermatocytes: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 61.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020454 Approved Supported Cytosol NA Yes "Cluster 42: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA020454: AB_1859492" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "unprognostic (5.53e-2)" "unprognostic (2.20e-2)" "unprognostic (1.11e-1)" "unprognostic (7.71e-2)" "unprognostic (2.13e-3)" "unprognostic (2.13e-3)" "unprognostic (1.63e-2)" "unprognostic (5.35e-2)" "unprognostic (2.21e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (1.11e-1)" "unprognostic (2.30e-1)" "unprognostic (3.51e-1)" "unprognostic (3.28e-1)" 15.7 13.4 10.2 12.2 10.7 42.0 13.4 12.7 19.2 13.1 10.5 11.9 14.7 12.8 9.7 13.8 12.1 9.8 13.5 10.5 10.4 16.4 15.7 11.2 16.8 10.0 10.7 15.7 13.4 9.0 12.6 11.9 10.3 12.3 11.9 8.7 12.6 7.7 32.5 13.6 11.9 7.4 9.3 12.2 12.9 31.3 11.4 12.3 12.7 12.7 13.2 18.8 12.8 11.8 52.7 38.1 21.4 38.7 16.1 22.6 41.6 35.1 25.8 38.5 28.6 52.9 37.2 74.9 53.7 24.4 55.2 35.5 57.5 25.7 58.4 40.6 43.4 55.1 38.7 47.3 28.6 97.9 41.2 19.6 21.9 44.9 39.4 16.2 25.6 27.8 128.3 46.2 32.0 83.8 95.0 102.1 75.9 56.8 57.0 59.7 43.0 70.1 22.8 24.8 40.6 38.7 47.7 66.2 39.7 39.6 28.1 49.8 30.8 37.5 59.9 83.3 68.1 48.9 67.8 146.0 27.3 97.9 47.6 61.3 9.0 9.3 10.9 10.3 12.1 11.7 10.9 11.7 9.4 13.7 12.5 12.5 3.6 16.4 15.3 11.2 12.8 5.9 10.2 10.7 12.7 19.2 10.5 10.4 10.0 10.7 10.3 9.3 11.4 11.8 31.3 25.6 47.0 10.7 46.1 64.6 78.7 37.3 35.3 27.1 26.3 36.6 32.3 22.8 50.2 22.0 41.7 43.7 45.9 31.1 35.2 45.0 248.5 43.8 50.1 39.6 35.3 29.9 24.7 46.0 75.5 41.0 42.8 44.2 53.7 50.1 18.5 30.6 39.6 21.9 17.9 39.0 26.4 24.5 41.3 37.3 39.4 37.8 19.6 13.1 42.9 19.3 44.3 24.1 20.6 50.2 32.9 31.2 36.9 79.2 36.4 31.0 43.4 29.0 39.5 63.7 64.8 238.7 131.9 33.5 62.1 55.4 43.2 58.3 51.9 91.5 DNPEP "ASPEP, DAP" ENSG00000123992 "Aspartyl aminopeptidase" Q9ULA0 2 219372043-219400022 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 364.4;Late spermatids: 462.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036398, HPA044860" Enhanced Supported Cytosol NA NA 2700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA036398: AB_10970915, HPA044860: AB_10961275" "unprognostic (3.71e-1)" "unprognostic (6.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.75e-1)" "unprognostic (2.54e-3)" "unprognostic (3.34e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-2)" "unprognostic (1.61e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-1)" "unprognostic (5.63e-3)" "unprognostic (3.49e-1)" "unprognostic (2.50e-1)" "unprognostic (1.85e-3)" 25.8 18.9 15.4 25.0 15.8 18.0 23.6 14.8 18.6 24.9 14.7 34.5 56.5 22.4 21.5 25.1 25.1 22.6 39.9 16.2 16.9 22.1 32.0 27.6 23.4 15.8 15.0 30.2 27.2 25.8 13.0 37.1 15.2 22.6 30.8 9.5 26.2 24.4 64.5 31.7 56.2 19.9 16.0 24.7 25.4 58.5 17.4 17.5 15.2 46.4 16.2 29.6 21.6 14.7 47.5 25.8 15.4 45.7 39.7 32.2 122.0 23.0 46.5 59.3 62.5 72.6 61.2 27.2 48.7 49.5 76.0 45.0 18.6 53.6 21.3 56.4 12.5 46.6 25.0 79.8 107.2 38.9 32.2 54.4 55.4 61.8 50.2 37.9 41.2 38.6 53.8 45.3 31.0 103.7 60.8 44.5 25.5 67.7 15.1 77.2 35.7 36.5 33.0 74.0 19.1 26.0 27.1 86.5 34.5 26.9 25.8 43.3 23.5 55.4 46.1 31.4 33.7 49.6 31.8 21.3 80.0 37.7 24.1 8.7 17.2 7.3 16.1 19.7 18.8 13.2 13.2 18.3 20.8 16.2 14.0 18.7 1.6 21.2 17.0 7.2 16.6 14.8 15.4 15.8 14.8 18.6 16.2 16.9 15.8 15.0 15.2 16.0 17.4 14.7 43.1 12.8 18.2 8.8 35.6 38.6 74.1 55.1 52.9 19.3 41.2 36.7 33.6 55.8 27.2 25.8 33.3 90.4 26.7 70.4 49.0 62.9 364.4 16.5 36.5 41.8 48.0 19.8 3.1 66.3 96.9 43.4 29.0 19.6 24.1 39.1 30.4 47.9 51.0 10.1 5.2 110.3 38.7 31.5 26.8 462.0 52.5 26.2 32.0 4.7 53.0 29.8 45.3 3.0 3.3 52.3 75.6 41.0 38.3 113.1 202.6 79.6 16.3 37.6 26.3 31.9 120.0 20.1 20.1 43.4 44.8 66.4 34.1 36.9 70.9 74.6 DNTTIP2 "ERBP, HSU15552, TdIF2" ENSG00000067334 "Deoxynucleotidyltransferase terminal interacting protein 2" Q5QJE6 1 93866284-93879918 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044502, HPA053707" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA044502: AB_10960277, HPA053707: AB_2682236" "unprognostic (2.95e-3)" "unprognostic (3.84e-2)" "unprognostic (6.21e-3)" "unprognostic (1.12e-2)" "unprognostic (2.41e-1)" "unprognostic (8.92e-2)" "prognostic unfavorable (1.90e-6)" "unprognostic (7.94e-2)" "unprognostic (5.57e-3)" "unprognostic (2.69e-2)" "unprognostic (2.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.80e-5)" "unprognostic (2.59e-1)" "unprognostic (8.41e-2)" "unprognostic (2.25e-1)" "unprognostic (1.06e-2)" 5.0 3.7 4.9 3.5 5.2 15.3 5.0 10.3 6.7 3.5 5.6 3.4 2.7 4.0 6.3 4.4 3.5 4.5 4.5 5.5 5.4 4.2 5.0 3.7 5.5 4.8 4.9 4.3 3.4 3.8 2.1 4.6 5.1 3.7 3.6 4.2 2.9 3.0 8.9 5.5 2.7 3.7 3.8 4.5 3.6 4.5 5.3 4.3 4.7 5.0 5.2 6.5 2.8 6.8 14.3 6.6 7.2 7.8 6.9 6.2 11.1 9.4 6.6 11.0 9.4 7.3 6.1 18.8 12.2 9.9 13.8 7.7 11.9 11.2 15.6 11.4 6.6 15.4 11.3 11.0 7.2 17.4 5.3 6.8 11.9 11.9 9.8 5.5 7.9 6.0 18.6 6.0 15.1 6.3 12.2 11.3 14.2 6.3 10.6 7.0 15.6 7.2 11.3 10.8 8.7 7.7 9.8 14.4 10.5 9.2 6.2 12.6 7.7 8.8 9.2 10.2 15.9 6.4 9.3 15.3 5.1 13.6 5.9 9.7 5.7 11.6 6.4 8.3 7.7 8.2 5.8 5.8 5.1 8.4 5.3 6.9 8.0 9.6 8.5 3.5 6.4 6.8 4.9 5.2 10.3 6.7 5.5 5.4 4.8 4.9 5.1 3.8 5.3 6.8 98.9 57.7 78.2 3.6 66.7 54.4 163.0 57.9 43.3 33.9 27.5 38.9 73.0 11.5 91.2 12.9 58.4 52.0 110.2 17.3 21.5 74.3 53.8 85.1 72.0 74.2 8.4 20.6 6.8 60.3 44.4 54.3 38.2 122.4 119.4 36.6 25.7 19.4 38.1 20.2 7.7 14.5 46.8 29.5 72.1 11.0 25.7 75.8 23.2 8.4 52.1 29.2 48.4 3.5 7.2 88.6 20.1 25.9 50.1 96.7 17.2 19.6 85.1 34.4 19.7 90.7 79.0 62.8 65.9 40.0 50.6 55.8 87.7 44.4 23.1 112.0 DOLK "DK1, KIAA1094, TMEM15" ENSG00000175283 "Dolichol kinase" Q9UPQ8 9 128945530-128947603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066767, HPA068706" Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli" Cytosol "HPA066767: AB_2732751, HPA068706: AB_2732118" "unprognostic (6.35e-2)" "unprognostic (2.69e-1)" "unprognostic (2.63e-1)" "unprognostic (1.30e-3)" "unprognostic (3.55e-1)" "unprognostic (2.81e-3)" "unprognostic (8.90e-3)" "unprognostic (3.26e-1)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.83e-2)" "prognostic favorable (5.53e-4)" "unprognostic (3.20e-2)" "unprognostic (1.06e-1)" "prognostic favorable (6.88e-5)" "unprognostic (6.13e-3)" 9.6 14.3 6.6 6.3 6.3 1.5 7.8 6.7 6.7 7.4 8.6 7.5 7.6 9.3 13.5 8.6 8.9 7.9 10.5 6.5 7.1 9.1 10.5 9.1 6.8 6.9 7.6 6.7 14.5 16.8 5.9 9.3 7.3 10.0 6.6 4.4 12.0 10.0 6.7 9.9 7.5 9.4 6.5 8.0 10.6 14.5 7.6 5.1 7.8 7.1 6.6 8.6 5.9 6.8 11.7 42.5 14.8 22.0 42.6 22.2 20.0 23.7 38.1 28.5 21.0 33.7 17.9 6.4 12.3 34.6 40.3 80.3 20.3 29.6 14.7 10.7 17.8 8.0 27.4 24.5 43.0 8.8 13.5 31.1 27.0 30.8 16.8 16.7 28.1 9.1 19.7 10.0 31.3 56.9 7.3 7.3 19.0 33.0 26.0 7.2 19.5 25.1 25.7 17.3 13.5 15.1 31.4 25.6 14.1 13.7 44.8 11.4 23.6 25.6 9.2 32.5 19.8 9.4 25.0 6.4 24.2 8.0 19.9 2.7 15.4 6.9 11.2 15.3 10.1 11.8 9.9 12.3 16.6 12.5 12.8 13.2 2.2 13.0 21.2 9.3 16.8 10.5 6.6 6.3 6.7 6.7 6.5 7.1 6.9 7.6 7.3 6.5 7.6 6.8 8.5 6.4 4.1 2.9 2.6 1.8 3.6 13.9 4.6 9.1 4.4 4.3 3.5 10.0 10.9 7.3 8.4 25.6 3.5 5.2 0.0 15.7 15.1 5.9 7.2 9.2 1.2 3.6 1.2 14.2 16.4 8.1 5.1 3.6 1.3 7.5 16.1 9.2 13.5 5.0 2.2 3.5 12.2 5.2 2.7 3.7 12.2 2.9 3.6 1.9 2.8 10.7 5.2 2.5 1.7 11.1 7.5 6.0 1.5 4.4 7.5 9.0 11.4 7.1 0.0 7.0 15.7 33.8 15.1 3.3 1.3 18.2 2.3 15.8 5.7 2.1 DUSP12 "DUSP1, YVH1" ENSG00000081721 "Dual specificity phosphatase 12" Q9UNI6 1 161749758-161757238 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008840 Uncertain Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA008840: AB_1847884" "unprognostic (3.51e-2)" "unprognostic (2.62e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-2)" "unprognostic (2.11e-1)" "unprognostic (4.04e-2)" "prognostic unfavorable (1.99e-5)" "unprognostic (1.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.25e-3)" "unprognostic (9.52e-2)" "unprognostic (2.42e-3)" "prognostic unfavorable (1.55e-7)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (3.25e-2)" "unprognostic (2.42e-1)" 13.3 9.6 12.1 9.1 12.5 30.9 14.1 14.3 14.6 13.8 12.1 12.9 7.6 14.3 8.9 10.3 12.5 6.7 9.4 12.0 12.4 14.4 9.4 11.4 13.8 12.2 12.2 13.6 13.6 8.2 9.5 11.2 12.3 11.0 10.5 13.2 10.9 9.5 7.4 10.9 12.4 11.0 12.3 14.1 11.5 6.7 12.0 11.7 12.1 7.3 13.0 13.1 11.5 13.3 32.6 28.2 33.1 21.7 17.2 18.5 30.4 25.9 33.7 39.2 29.9 42.1 28.2 19.9 25.7 31.9 24.4 22.7 26.0 32.0 38.0 25.5 22.0 17.8 27.7 28.4 36.4 38.6 17.1 25.4 34.6 34.1 61.0 22.2 27.6 27.2 31.7 20.9 28.3 30.0 22.7 43.2 52.1 35.2 43.1 32.2 32.0 32.9 22.2 39.3 20.6 43.6 21.9 36.2 44.1 36.2 31.3 43.6 19.3 33.3 30.8 26.3 55.6 35.3 31.0 47.0 20.3 38.1 33.3 32.0 16.9 13.7 18.4 19.5 22.9 19.2 20.8 17.8 22.0 20.0 19.6 21.8 6.8 28.4 12.2 10.0 19.5 12.9 12.1 12.5 14.3 14.6 12.0 12.4 12.2 12.2 12.3 12.3 12.0 13.3 22.9 19.2 12.8 8.1 25.5 13.6 14.4 25.9 25.6 15.9 13.4 16.1 5.0 8.6 15.6 7.3 8.4 21.7 26.4 4.8 21.5 22.2 4.2 7.4 13.7 18.4 11.3 16.2 11.9 24.3 22.7 17.3 11.7 7.2 18.3 18.7 18.5 8.2 20.5 10.1 14.8 9.8 8.2 20.6 16.2 1.2 8.7 15.4 10.6 10.3 22.1 15.8 33.0 12.1 14.4 21.2 6.5 17.7 27.5 17.1 8.6 18.5 7.0 19.6 0.0 13.2 24.5 13.9 12.6 18.2 13.1 17.6 23.5 16.4 12.1 12.0 EDARADD ENSG00000186197 "EDAR associated death domain" Q8WWZ3 1 236348257-236502915 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 8.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 26.7;granulocytes: 22.7;Syncytiotrophoblasts: 22.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "basophil: 49.5" "Lineage enriched" "Detected in many" 8 "granulocytes: 49.5" "Cell line enhanced" "Detected in some" "BEWO: 15.9;HDLM-2: 13.2;HMC-1: 52.7;RT4: 45.3;T-47d: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA018836 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA018836: AB_1847984" "unprognostic (3.74e-1)" "unprognostic (3.10e-2)" "unprognostic (2.92e-1)" "unprognostic (2.12e-2)" "unprognostic (2.06e-3)" "unprognostic (3.12e-3)" "unprognostic (9.94e-2)" "unprognostic (2.96e-2)" "unprognostic (2.62e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (2.57e-2)" "unprognostic (5.72e-2)" "unprognostic (3.00e-1)" "unprognostic (2.47e-1)" "unprognostic (1.90e-2)" "unprognostic (9.62e-3)" 0.4 0.1 0.2 0.4 0.1 0.4 4.8 0.1 0.1 0.7 0.0 0.3 0.4 0.4 5.2 3.3 1.2 0.8 0.9 0.1 0.1 1.1 0.3 0.7 1.2 0.2 0.2 0.4 3.8 0.1 0.1 4.9 0.1 3.6 0.3 0.0 1.4 6.1 0.0 5.8 0.3 0.1 0.1 1.2 6.3 3.4 0.2 2.3 6.4 0.0 2.6 8.7 1.0 0.1 0.0 3.8 0.3 0.0 0.0 0.0 15.9 0.0 0.0 1.3 0.8 1.0 0.0 0.0 0.0 0.2 4.3 8.8 6.5 9.6 1.2 13.2 7.6 0.1 0.1 1.4 0.0 0.4 52.7 0.0 2.7 0.9 0.8 0.0 0.0 1.8 0.4 0.0 0.0 0.4 0.3 0.0 3.9 0.0 0.0 3.4 0.1 0.0 0.0 45.3 0.4 0.3 0.0 1.2 0.2 0.3 12.6 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 49.5 0.3 0.1 3.1 0.4 4.1 0.1 4.7 6.1 0.5 0.2 0.4 3.2 0.3 5.3 0.2 0.1 5.1 2.1 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.3 0.0 1.3 0.0 0.4 6.9 7.3 16.3 13.1 0.0 7.1 7.4 4.1 5.7 8.4 0.0 0.0 26.7 3.0 0.1 3.9 1.7 10.6 0.2 1.2 1.2 0.0 2.5 0.5 0.9 14.2 1.1 5.1 0.4 22.7 2.8 5.0 0.5 3.4 0.0 0.6 0.1 8.2 1.5 8.9 9.3 0.3 0.6 12.4 1.0 3.7 0.6 0.0 1.0 0.4 0.6 0.0 0.4 1.8 4.2 0.1 0.4 3.2 0.1 0.0 1.4 6.1 13.4 3.7 6.5 5.3 22.6 6.2 0.3 0.0 5.3 EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 189.5;Urothelial cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 103.8;TIME: 172.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Approved "Plasma membrane" NA NA 440000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA052729: AB_2681928, HPA066751: AB_2685713" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.34e-3)" "unprognostic (3.36e-2)" "unprognostic (3.46e-2)" "unprognostic (4.48e-3)" "unprognostic (1.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.74e-1)" "unprognostic (6.93e-2)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.72e-1)" 21.6 4.6 3.1 11.8 3.2 10.9 16.4 7.5 3.5 9.4 5.3 12.1 5.5 9.6 10.5 15.0 9.8 15.2 27.8 3.3 3.8 14.3 9.6 15.0 12.8 4.8 4.0 5.6 14.3 12.8 5.8 8.3 4.8 9.5 10.2 6.1 10.4 9.7 4.4 14.3 12.4 12.9 5.2 7.4 9.9 2.8 4.0 5.3 18.4 4.7 8.8 23.8 9.0 6.6 28.7 9.8 9.3 9.6 4.6 6.5 8.1 14.9 31.4 25.9 36.1 41.4 16.1 5.9 39.2 18.8 51.6 28.4 13.9 32.6 19.0 35.7 11.7 8.7 13.5 7.1 11.3 4.0 24.4 5.5 12.6 26.3 28.8 9.9 103.8 8.7 9.2 6.6 21.1 12.2 4.2 4.5 7.1 27.8 33.5 0.1 24.5 9.4 23.4 57.0 15.4 6.5 10.9 23.2 17.0 9.0 22.9 5.6 172.8 8.1 15.7 30.5 73.1 18.1 30.9 12.4 10.3 9.4 71.6 1.1 14.0 9.0 4.0 12.4 6.1 2.1 6.2 5.0 14.9 2.6 2.6 3.8 2.3 4.4 5.2 2.5 7.9 8.0 3.1 3.2 7.5 3.5 3.3 3.8 4.8 4.0 4.8 5.2 4.0 6.6 94.9 6.4 44.2 3.9 20.0 81.6 189.5 68.1 34.1 4.9 31.4 20.1 36.6 30.0 69.0 44.1 31.3 10.1 22.2 96.0 7.9 71.3 16.1 66.1 9.7 114.9 22.6 5.7 1.2 62.6 20.4 21.3 25.5 72.4 61.6 16.2 54.7 8.7 89.0 1.7 0.7 22.5 28.5 35.6 52.7 34.7 7.5 46.3 19.6 12.2 53.5 37.5 4.1 26.7 2.7 75.1 70.9 4.9 31.5 49.9 71.4 4.6 60.8 27.8 13.1 8.0 29.0 5.4 8.2 29.3 79.8 17.4 27.8 21.2 37.3 200.1 EIF1AD "haponin, MGC11102" ENSG00000175376 "Eukaryotic translation initiation factor 1A domain containing" Q8N9N8 11 65996545-66002176 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054991, HPA058735" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Vesicles" Cytosol "HPA054991: AB_2682664, HPA058735: AB_2683802" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (3.03e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (8.63e-5)" "unprognostic (1.86e-2)" "unprognostic (1.17e-1)" "unprognostic (8.76e-2)" "unprognostic (1.36e-3)" "unprognostic (2.31e-1)" "unprognostic (1.59e-3)" "unprognostic (7.63e-3)" "unprognostic (1.40e-1)" "unprognostic (1.28e-3)" "unprognostic (3.96e-1)" 15.7 17.7 15.3 19.9 15.8 44.6 16.0 18.7 19.8 13.1 14.4 15.8 15.1 15.9 16.2 21.0 15.3 13.0 17.1 16.4 17.7 15.2 17.3 15.0 23.4 16.1 15.7 20.4 19.2 17.1 16.6 21.1 16.3 13.4 14.7 16.6 16.8 14.9 27.2 23.1 16.9 14.8 14.8 20.0 16.1 19.4 17.3 19.9 13.8 23.3 27.6 17.1 14.5 18.4 51.0 43.9 35.0 35.9 27.6 28.8 32.8 36.4 34.6 44.2 37.7 44.8 47.5 38.2 62.6 41.2 38.0 34.9 42.2 48.8 41.5 35.1 21.7 54.4 52.0 46.4 33.7 50.3 41.8 24.1 41.9 65.3 44.1 31.2 31.0 40.9 81.1 54.4 64.7 68.7 46.6 55.1 25.9 23.3 47.5 50.3 35.9 75.0 25.6 31.8 26.5 31.2 39.3 54.7 41.5 28.1 53.1 31.0 36.5 59.7 39.9 47.8 36.1 66.7 85.5 79.8 42.9 33.8 39.5 52.6 20.5 13.5 17.7 16.6 13.6 19.4 15.0 13.0 21.3 19.0 14.1 13.5 13.1 16.4 21.3 12.7 15.3 13.3 15.3 15.8 18.7 19.8 16.4 17.7 16.1 15.7 16.3 14.8 17.3 18.4 8.2 3.2 5.4 3.3 16.2 37.7 12.2 13.4 12.5 7.2 14.2 9.1 16.2 14.3 7.3 5.5 14.6 16.3 17.7 11.6 15.6 12.7 18.3 9.0 8.3 11.6 2.4 21.0 3.0 13.1 23.0 11.4 7.1 10.5 12.7 31.7 16.4 16.5 24.5 11.8 2.8 11.2 6.1 10.4 29.5 14.3 12.2 14.4 12.4 1.0 17.6 10.5 17.5 5.5 4.5 29.0 15.2 5.7 22.6 13.2 13.8 15.7 10.6 18.5 6.6 9.8 27.0 31.3 23.2 15.7 48.9 25.3 16.2 7.4 10.9 13.2 EIF2B3 "EIF-2B, EIF2Bgamma" ENSG00000070785 "Eukaryotic translation initiation factor 2B subunit gamma" Q9NR50 1 44850522-44986722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024213, HPA024218, HPA024219" Supported Supported Vesicles,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "HPA024213: AB_1848067, HPA024218: AB_1848068, HPA024219: AB_1848069" "unprognostic (2.12e-2)" "unprognostic (7.49e-2)" "unprognostic (4.37e-3)" "unprognostic (5.14e-2)" "unprognostic (1.57e-2)" "unprognostic (4.45e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (4.55e-2)" "unprognostic (1.14e-2)" "unprognostic (7.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.36e-1)" "unprognostic (5.38e-2)" "unprognostic (6.98e-2)" "unprognostic (7.80e-2)" "unprognostic (5.69e-3)" "unprognostic (2.73e-2)" 23.6 27.2 11.4 11.6 10.9 10.9 21.9 13.2 15.6 18.7 10.1 17.5 8.6 17.0 12.5 17.4 16.3 9.6 40.6 11.2 11.6 15.4 24.7 13.5 14.3 11.9 12.1 18.2 16.9 30.0 15.8 9.7 12.8 15.0 13.4 19.0 25.1 13.7 77.0 17.6 10.7 19.4 11.0 14.9 14.2 19.3 11.2 13.3 12.5 48.0 14.5 17.7 17.1 14.0 35.4 26.9 30.9 25.5 36.3 43.1 36.2 56.1 42.2 56.5 52.9 39.0 20.7 90.6 39.9 43.2 45.0 20.6 65.3 48.6 69.5 32.5 58.1 44.3 29.3 38.4 46.2 71.2 24.3 29.3 25.8 61.0 69.9 26.5 52.8 30.1 106.1 31.6 62.3 23.1 69.7 30.2 42.0 38.8 52.7 54.7 51.3 65.7 28.7 15.7 53.2 20.5 55.1 63.8 37.4 40.7 24.7 32.8 28.3 35.9 42.9 53.4 73.7 31.6 37.9 68.9 27.9 59.5 43.1 1.6 23.4 3.9 18.6 37.2 22.8 14.8 18.3 21.1 37.0 18.9 22.9 23.6 2.1 25.5 33.1 25.3 17.6 21.4 11.4 10.9 13.2 15.6 11.2 11.6 11.9 12.1 12.8 11.0 11.2 14.0 13.9 6.4 22.0 24.8 15.8 13.8 19.0 33.0 10.8 15.1 15.8 16.8 79.2 15.7 24.9 5.5 20.9 25.1 12.1 4.5 29.4 18.9 26.1 17.0 23.0 14.4 3.6 15.3 39.9 15.8 22.6 22.6 13.7 11.5 25.9 21.1 3.9 22.6 24.8 21.9 44.5 7.0 20.3 10.7 11.2 11.3 26.4 15.4 17.8 26.2 30.1 21.7 10.3 29.1 35.7 13.7 6.9 25.2 22.6 17.1 5.7 23.1 34.2 21.8 26.3 19.7 45.4 45.5 23.6 17.1 14.9 14.9 13.5 40.4 9.4 13.9 EIF2S1 "EIF-2alpha, EIF2, EIF2A" ENSG00000134001 "Eukaryotic translation initiation factor 2 subunit alpha" P05198 14 67360328-67386516 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011663, HPA064885" Supported Enhanced Cytosol NA NA 210000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB011663: AB_2096478, HPA064885: AB_2685382" "unprognostic (1.86e-2)" "unprognostic (8.33e-2)" "unprognostic (4.31e-2)" "unprognostic (2.46e-2)" "unprognostic (3.78e-2)" "unprognostic (1.78e-3)" "prognostic unfavorable (4.73e-7)" "unprognostic (4.14e-3)" "unprognostic (4.49e-1)" "unprognostic (1.68e-2)" "prognostic unfavorable (4.97e-4)" "unprognostic (2.95e-1)" "unprognostic (1.21e-2)" "unprognostic (1.73e-1)" "unprognostic (4.65e-1)" "unprognostic (1.59e-2)" "prognostic unfavorable (7.11e-4)" 28.3 24.5 12.5 29.9 14.0 25.0 25.7 15.1 17.8 18.1 10.4 25.0 21.5 19.4 19.6 38.8 15.8 21.5 28.7 14.6 14.1 24.5 35.3 18.4 30.4 13.7 12.7 17.1 26.3 22.9 9.4 26.3 13.6 22.1 26.7 21.2 18.3 22.3 49.4 23.7 21.5 27.0 13.8 19.8 19.8 33.4 13.5 27.9 27.9 40.6 33.5 39.1 19.0 16.6 265.7 86.4 59.8 92.3 56.4 63.4 127.8 115.5 68.3 127.4 110.7 101.6 92.2 118.7 57.0 87.4 85.7 100.4 139.1 110.3 192.7 86.9 51.9 76.9 80.0 70.4 59.2 82.7 71.9 52.4 62.6 113.9 172.5 49.8 105.4 73.8 132.6 89.6 127.3 131.3 113.7 64.7 61.1 157.9 142.9 85.7 99.0 84.6 78.2 120.0 85.9 60.7 83.0 96.5 91.1 52.3 164.5 70.8 81.3 167.4 180.7 82.0 124.4 77.0 90.4 180.7 97.1 145.3 110.2 51.4 50.6 33.0 47.4 71.0 58.4 55.4 54.5 51.7 70.1 45.8 50.3 51.5 6.9 58.6 62.8 48.0 64.3 70.7 12.5 14.0 15.1 17.8 14.6 14.1 13.7 12.7 13.6 13.8 13.5 16.6 64.1 28.9 40.2 17.3 44.1 142.8 88.2 77.2 37.5 22.1 32.0 30.1 92.8 30.0 55.8 22.0 12.5 78.7 38.0 23.3 70.5 89.6 81.0 34.6 48.9 60.3 13.1 64.2 21.7 63.0 104.7 51.2 34.1 44.8 35.5 35.7 26.4 39.8 70.4 37.0 20.9 30.6 61.1 37.9 51.3 33.4 31.1 40.7 51.6 15.9 61.3 32.2 36.0 15.1 23.8 70.8 18.3 40.6 56.7 79.9 26.6 65.1 35.0 35.2 26.3 60.7 85.9 204.9 96.3 49.7 130.4 93.4 46.1 57.9 39.7 79.1 EIF2S2 "EIF2, EIF2beta, PPP1R67" ENSG00000125977 "Eukaryotic translation initiation factor 2 subunit beta" P20042 20 34088309-34112243 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034415, HPA041262, HPA041332" Approved Supported "Nucleoli,Endoplasmic reticulum" NA NA 480000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" Nucleoli "CAB034415: AB_2095998, HPA041262: AB_2677381, HPA041332: AB_2677417" "unprognostic (5.76e-3)" "unprognostic (7.12e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (8.74e-4)" "unprognostic (1.02e-1)" "unprognostic (1.47e-3)" "prognostic unfavorable (3.23e-5)" "unprognostic (9.36e-3)" "unprognostic (2.39e-1)" "unprognostic (6.55e-3)" "unprognostic (3.04e-3)" "unprognostic (1.25e-2)" "prognostic unfavorable (9.64e-10)" "unprognostic (2.52e-2)" "unprognostic (1.82e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-2)" 50.7 49.2 40.1 44.0 42.1 45.0 42.3 43.1 54.5 34.8 39.8 45.8 38.3 33.7 37.9 61.2 30.6 32.5 46.2 39.0 41.7 54.0 59.2 46.8 52.8 44.3 41.3 32.0 81.4 35.8 27.7 54.2 43.9 35.0 42.8 23.7 43.5 33.9 100.8 39.0 37.6 40.5 43.6 37.9 50.8 37.1 41.6 46.6 42.4 64.0 56.3 63.1 37.9 48.4 211.9 139.1 103.4 125.5 99.1 149.3 196.6 188.7 180.2 184.1 184.6 493.4 144.5 188.5 135.1 171.9 204.1 194.5 169.7 310.6 222.0 61.0 92.3 373.8 110.0 254.5 254.7 241.9 116.7 153.6 259.1 182.7 270.2 125.8 195.5 273.7 223.6 174.8 153.5 135.8 226.0 201.3 100.6 243.7 251.1 128.2 176.0 176.2 145.5 174.2 104.7 71.3 209.3 125.2 403.7 119.2 189.9 282.4 132.8 208.7 129.0 132.5 179.8 162.4 153.8 195.9 196.5 185.0 155.1 54.2 77.1 64.8 54.7 89.0 68.1 84.8 77.2 77.2 75.8 71.2 72.0 72.8 47.3 74.9 83.8 105.3 96.1 64.0 40.1 42.1 43.1 54.5 39.0 41.7 44.3 41.3 43.9 43.6 41.6 48.4 157.4 169.9 162.1 13.7 167.8 180.5 326.3 384.9 81.4 60.5 171.7 154.6 145.1 223.1 241.7 139.8 31.3 359.2 139.6 145.7 307.2 344.2 314.9 182.9 160.1 199.2 126.7 300.7 17.6 529.2 394.4 128.5 110.6 139.1 144.4 80.1 253.4 497.1 243.0 42.1 17.1 229.6 215.7 223.1 119.3 163.7 126.5 147.0 119.2 16.9 286.8 92.8 126.7 17.1 25.2 519.3 133.8 129.4 182.6 292.7 141.5 335.0 207.7 95.3 111.7 102.6 226.6 446.4 211.6 132.7 174.5 641.7 124.0 220.6 200.4 343.8 EIF3A "EIF3, eIF3-p170, eIF3-theta, EIF3S10, KIAA0139, TIF32" ENSG00000107581 "Eukaryotic translation initiation factor 3 subunit A" Q14152 10 119033670-119080823 "Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038315, HPA038316" Enhanced Supported Nucleoplasm,Cytosol Yes No 110000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA038315: AB_10672588, HPA038316: AB_10673168" "unprognostic (8.15e-2)" "unprognostic (2.09e-2)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "unprognostic (3.19e-1)" "unprognostic (1.47e-1)" "unprognostic (2.16e-1)" "unprognostic (1.84e-1)" "unprognostic (9.38e-2)" "unprognostic (3.84e-3)" "unprognostic (9.07e-2)" "unprognostic (5.48e-3)" "unprognostic (8.07e-2)" "unprognostic (1.20e-1)" "unprognostic (9.07e-2)" "unprognostic (1.89e-2)" 83.0 53.2 27.5 73.7 30.9 120.7 62.5 28.4 31.8 48.8 38.0 62.9 65.8 60.1 34.9 69.3 44.8 50.1 69.0 25.7 33.7 58.1 77.9 49.5 75.1 34.8 30.0 61.7 155.1 70.2 24.4 57.0 35.4 55.5 63.9 31.6 73.3 46.3 178.2 69.9 60.0 62.8 31.6 57.4 72.8 44.8 32.4 78.3 70.3 89.8 74.6 76.4 51.8 32.4 258.5 190.9 154.0 211.6 163.6 235.0 119.4 228.9 235.9 144.0 143.7 181.2 165.5 300.2 83.2 190.3 113.3 252.0 202.5 175.7 203.5 166.1 166.3 258.3 143.6 203.2 186.2 382.3 183.9 204.6 193.0 212.7 362.8 240.7 165.7 119.8 269.7 191.9 188.7 152.5 159.4 179.8 147.8 99.4 96.3 162.1 332.1 143.7 137.0 213.9 71.6 151.3 180.2 166.9 244.9 132.0 107.2 241.1 245.6 138.7 128.0 147.1 335.8 164.9 194.0 286.9 147.2 368.2 97.6 49.0 38.2 23.9 27.4 41.8 31.7 25.6 33.1 25.2 36.1 24.7 22.6 24.7 10.0 26.6 58.1 20.5 50.9 28.3 27.5 30.9 28.4 31.8 25.7 33.7 34.8 30.0 35.4 31.6 32.4 32.4 122.1 233.9 323.8 24.5 147.3 304.2 279.1 129.0 203.7 60.1 155.8 133.7 320.7 111.5 198.5 64.4 62.6 169.1 181.1 130.2 27.4 157.2 199.4 230.3 248.6 145.3 141.2 270.0 32.7 185.4 159.5 152.5 159.0 371.8 145.4 132.6 74.3 184.5 126.3 43.7 34.9 168.2 87.5 200.3 169.0 119.1 108.7 196.5 147.7 29.0 235.9 78.2 135.9 24.6 38.9 192.8 105.4 117.8 258.6 253.6 98.5 58.7 158.3 54.1 59.2 209.7 221.6 158.0 112.9 255.3 363.8 252.3 171.1 145.0 227.7 302.3 EIF3D "eIF3-p66, eIF3-zeta, EIF3S7" ENSG00000100353 "Eukaryotic translation initiation factor 3 subunit D" O15371 22 36510855-36529184 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045882, HPA063330, HPA066216" Approved Supported Cytosol NA NA 36000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA045882: AB_2679482, HPA063330: AB_2684988, HPA066216: AB_2685637" "unprognostic (4.98e-2)" "unprognostic (2.22e-1)" "unprognostic (8.74e-3)" "unprognostic (6.50e-3)" "unprognostic (1.39e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (8.10e-5)" "unprognostic (1.47e-1)" "unprognostic (2.58e-1)" "unprognostic (9.98e-2)" "unprognostic (5.54e-3)" "unprognostic (3.93e-2)" "unprognostic (5.49e-2)" "unprognostic (2.14e-2)" "unprognostic (1.72e-1)" "unprognostic (5.22e-2)" "unprognostic (9.78e-2)" 121.7 84.3 46.1 105.2 48.9 176.9 184.5 48.6 48.2 127.8 59.0 118.7 107.3 121.7 123.7 144.5 158.1 84.6 95.0 46.2 48.0 88.4 88.0 87.5 174.1 51.1 48.6 193.3 228.0 108.1 55.3 109.8 51.3 97.8 135.5 45.6 132.8 102.2 152.1 153.4 100.1 118.7 48.9 138.6 129.3 63.5 50.8 162.6 113.5 93.1 211.8 134.7 116.2 52.2 312.4 171.3 172.2 197.2 237.8 462.3 287.8 235.2 321.2 319.5 313.7 270.7 171.1 395.3 173.4 271.8 202.4 230.9 295.1 374.5 320.7 215.7 313.6 215.4 151.9 209.6 428.2 507.5 214.4 419.6 427.7 357.1 515.0 365.1 347.5 128.0 238.3 195.9 363.6 194.0 180.3 281.0 188.5 484.9 141.6 318.1 278.0 305.0 314.2 214.9 135.9 190.7 153.6 311.3 337.4 180.0 196.7 472.5 243.9 247.9 222.6 188.3 333.6 247.5 171.8 316.9 252.1 318.1 242.7 166.7 383.7 141.3 320.3 353.5 520.4 518.1 461.1 381.1 528.9 509.2 558.2 455.7 95.1 402.3 348.9 303.3 608.7 826.1 46.1 48.9 48.6 48.2 46.2 48.0 51.1 48.6 51.3 48.9 50.8 52.2 115.6 60.9 92.0 13.7 184.7 212.9 287.1 299.1 134.9 37.3 231.9 216.8 67.9 130.1 167.1 46.0 31.3 224.2 151.5 68.2 150.6 191.7 126.3 108.4 95.3 141.7 112.7 101.4 8.5 207.8 240.4 99.4 78.0 88.1 187.3 128.9 126.7 41.0 219.7 25.2 8.7 149.1 109.9 211.0 176.1 46.4 138.5 121.7 129.9 8.4 275.1 75.6 137.0 10.6 12.5 185.6 134.7 108.3 72.5 230.6 176.5 160.1 119.9 46.2 72.3 147.9 260.8 106.0 83.2 140.3 215.8 246.1 159.8 162.2 219.7 288.0 EIF3H "eIF3-gamma, eIF3-p40, EIF3S3" ENSG00000147677 "Eukaryotic translation initiation factor 3 subunit H" O15372 8 116642130-116766925 "Cancer-related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 1808.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023117, HPA023553" Approved Approved Cytosol NA NA 38000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA023117: AB_1848076, HPA023553: AB_1848077" "prognostic unfavorable (5.26e-4)" "prognostic unfavorable (8.07e-4)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (6.69e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (8.34e-4)" "unprognostic (3.63e-2)" "unprognostic (1.37e-1)" "unprognostic (1.96e-1)" "unprognostic (1.12e-3)" "unprognostic (3.08e-1)" "unprognostic (3.77e-2)" "unprognostic (6.36e-2)" "unprognostic (1.48e-1)" "unprognostic (9.19e-2)" "unprognostic (1.11e-1)" 212.3 164.1 111.0 168.6 119.8 341.1 246.8 114.8 138.5 270.2 104.2 233.1 172.7 212.7 180.0 232.0 211.3 159.2 223.6 106.9 121.0 184.2 181.0 149.2 283.2 118.4 113.7 392.6 249.9 184.0 147.6 161.7 120.6 179.5 201.9 131.0 219.9 158.1 372.6 201.8 167.9 182.5 124.2 171.4 195.2 144.4 111.9 291.0 215.5 278.3 307.1 221.7 237.0 130.2 455.0 256.2 302.2 264.9 390.3 678.0 300.4 292.5 374.4 316.7 306.5 266.1 521.6 719.4 288.6 307.2 230.4 284.4 335.5 445.2 395.5 468.5 271.9 636.0 212.0 400.6 487.8 278.1 325.7 630.0 606.4 287.0 659.5 536.4 348.8 555.5 548.2 370.1 360.4 335.7 778.2 388.1 308.6 995.6 404.5 443.6 201.8 517.6 479.8 327.8 341.6 412.4 153.5 1808.1 504.9 294.8 538.3 550.5 322.5 201.8 374.5 301.5 388.8 591.3 574.4 591.3 280.2 483.4 281.8 165.2 361.6 132.2 217.9 356.8 358.9 438.1 393.5 317.9 468.6 381.4 511.0 432.1 74.4 314.6 366.1 260.9 477.7 585.7 111.0 119.8 114.8 138.5 106.9 121.0 118.4 113.7 120.6 124.2 111.9 130.2 138.9 182.7 210.7 42.4 314.6 337.5 423.7 444.2 266.9 62.7 317.2 273.4 160.8 191.6 253.0 93.8 12.5 488.0 211.4 117.0 448.0 290.5 387.2 81.2 196.0 185.8 201.0 215.8 47.8 380.5 551.0 183.7 125.9 159.2 194.4 166.2 168.8 104.6 332.4 26.9 49.9 301.6 170.9 386.6 402.8 265.0 331.5 261.5 209.9 51.5 509.9 136.0 224.6 58.3 70.3 292.9 240.5 220.1 166.7 338.5 260.2 443.9 92.9 76.8 197.2 251.5 504.1 233.0 176.0 317.4 356.5 577.2 287.5 241.4 345.5 481.2 EIF3I "eIF3-beta, eIF3-p36, EIF3S2, TRIP-1" ENSG00000084623 "Eukaryotic translation initiation factor 3 subunit I" Q13347 1 32221077-32245397 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA029939, HPA029940" Enhanced Approved Cytosol NA NA 70000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA029939: AB_10611109, HPA029940: AB_10600878" "unprognostic (4.48e-2)" "unprognostic (1.01e-1)" "unprognostic (7.82e-2)" "prognostic favorable (2.14e-4)" "unprognostic (3.86e-2)" "unprognostic (2.32e-2)" "prognostic unfavorable (4.21e-4)" "unprognostic (9.26e-2)" "unprognostic (1.28e-1)" "unprognostic (4.94e-2)" "unprognostic (1.00e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (4.81e-6)" "unprognostic (1.80e-1)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (8.47e-2)" 123.4 146.6 69.2 109.3 70.2 103.5 164.5 76.9 87.3 126.4 78.7 137.2 96.4 104.4 162.3 154.7 141.7 93.7 127.0 68.6 71.8 123.8 152.8 99.6 134.0 72.8 71.2 154.1 134.8 141.9 78.3 116.2 73.3 113.2 163.5 52.5 127.2 120.4 247.3 119.8 91.0 144.9 72.7 84.7 118.8 48.9 73.6 164.5 131.8 220.5 187.1 158.0 107.1 79.0 404.3 293.3 207.4 463.5 326.9 427.2 209.3 301.3 514.2 517.2 401.5 317.1 418.3 533.0 320.7 514.0 315.9 265.9 498.6 549.9 667.0 234.4 348.1 288.9 245.8 362.7 352.5 559.1 295.4 413.1 471.2 528.0 569.5 363.4 478.8 363.8 699.1 223.4 502.4 276.3 469.3 370.2 624.2 445.4 339.4 344.1 356.3 509.0 515.9 300.9 325.6 343.4 276.6 351.7 562.1 366.6 282.9 270.7 286.4 333.2 360.3 523.8 653.5 377.7 495.7 487.4 365.2 419.6 440.2 113.8 196.6 93.7 164.4 206.7 180.4 182.1 171.8 160.5 235.8 164.9 148.4 140.5 15.2 183.0 162.0 177.0 219.6 299.8 69.2 70.2 76.9 87.3 68.6 71.8 72.8 71.2 73.3 72.7 73.6 79.0 136.9 51.3 76.7 6.8 114.5 136.6 227.6 275.6 84.8 38.0 123.6 114.7 41.9 87.2 136.4 51.5 10.4 300.8 118.2 90.1 133.1 295.4 60.8 79.2 114.2 163.5 138.6 69.0 6.8 272.8 341.4 125.6 71.9 85.1 115.3 120.3 89.6 77.1 224.1 13.5 8.2 184.0 148.5 108.1 131.5 29.5 172.4 108.8 144.1 5.6 190.8 69.9 112.3 7.1 10.7 284.4 115.6 139.2 107.5 173.9 125.9 216.2 99.2 41.8 92.1 108.0 338.3 76.5 76.6 121.8 141.4 342.3 115.1 192.3 213.5 219.9 EIF3M "FLJ29030, GA17, hfl-B5, PCID1, TANGO7" ENSG00000149100 "Eukaryotic translation initiation factor 3 subunit M" Q7L2H7 11 32583798-32606264 "Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031063 Approved Approved Cytosol NA NA 130000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA031063: AB_10602128" "unprognostic (4.40e-2)" "unprognostic (1.47e-1)" "unprognostic (2.64e-2)" "unprognostic (7.16e-2)" "unprognostic (3.18e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.28e-9)" "unprognostic (5.79e-3)" "unprognostic (2.27e-2)" "unprognostic (1.83e-2)" "unprognostic (4.14e-3)" "unprognostic (1.91e-1)" "unprognostic (5.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.12e-1)" "unprognostic (1.10e-2)" "unprognostic (6.42e-2)" 96.9 105.0 49.5 72.4 53.0 141.4 135.1 51.9 71.6 89.6 51.1 80.6 77.1 96.5 106.6 95.0 146.4 70.8 86.1 52.0 56.1 112.7 108.4 60.1 122.7 52.3 49.5 162.9 131.6 64.7 49.4 79.8 51.5 71.3 98.4 43.3 78.6 82.3 103.1 102.5 60.2 98.3 52.7 71.1 88.0 74.3 51.7 131.2 107.6 82.4 146.6 113.6 79.5 55.9 173.6 219.0 171.0 218.8 222.7 318.2 251.5 176.1 242.7 264.5 255.6 284.5 124.1 445.6 118.1 201.6 226.7 214.1 301.1 319.4 328.2 151.4 372.3 201.2 164.5 303.4 322.1 473.9 276.4 287.4 355.1 178.8 434.6 221.5 301.3 234.6 403.8 151.2 293.8 204.1 238.3 494.4 188.4 230.8 334.2 192.0 430.7 209.9 291.4 321.4 131.3 203.0 125.2 233.5 279.9 187.0 259.3 279.6 142.1 164.6 188.0 353.0 540.2 183.5 248.8 324.0 148.2 284.3 166.1 71.9 211.7 65.7 99.7 189.3 137.6 144.9 136.9 127.3 258.4 117.9 141.1 129.9 24.8 142.3 142.8 154.8 156.5 186.0 49.5 53.0 51.9 71.6 52.0 56.1 52.3 49.5 51.5 52.7 51.7 55.9 82.7 83.3 66.4 19.2 147.5 212.9 256.2 372.8 189.0 44.7 112.9 132.3 41.1 81.5 168.0 60.7 20.9 261.8 127.8 47.1 131.0 187.3 154.9 76.4 168.8 106.3 72.4 148.5 23.8 250.7 284.0 121.9 103.0 104.3 158.4 123.6 98.6 73.3 197.1 10.1 23.5 132.3 156.6 250.6 209.6 55.2 133.9 153.6 110.3 12.2 283.6 70.0 131.8 20.1 21.6 171.8 87.4 120.4 132.4 212.0 86.3 220.6 87.6 42.5 72.3 140.1 254.9 109.4 72.6 159.5 225.0 243.0 154.1 228.3 169.9 252.9 EIF4A1 "DDX2A, EIF-4A, EIF4A" ENSG00000161960 "Eukaryotic translation initiation factor 4A1" P60842 17 7572824-7579006 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1342.5;Basal respiratory cells: 1913.6;Langerhans cells: 1330.1;Suprabasal keratinocytes: 1233.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011689, HPA068286" Uncertain Approved Cytosol NA NA 4100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB011689: AB_732122, HPA068286: AB_2685968" "unprognostic (1.49e-2)" "unprognostic (2.41e-1)" "unprognostic (8.00e-2)" "unprognostic (2.17e-1)" "unprognostic (2.49e-1)" "unprognostic (2.12e-3)" "unprognostic (7.25e-2)" "unprognostic (2.89e-2)" "unprognostic (2.72e-2)" "unprognostic (2.11e-2)" "unprognostic (2.65e-2)" "unprognostic (5.19e-3)" "prognostic unfavorable (1.76e-8)" "unprognostic (1.91e-1)" "unprognostic (5.96e-2)" "unprognostic (1.16e-1)" "unprognostic (1.13e-2)" 500.5 373.3 110.2 296.5 113.4 416.2 354.2 118.1 129.6 287.0 116.7 260.6 199.7 290.3 196.6 566.2 307.9 229.5 229.7 112.7 123.9 274.2 328.3 339.0 286.3 128.9 119.1 302.8 360.5 150.4 190.2 301.9 125.9 219.2 289.5 118.5 268.6 168.7 281.2 375.5 228.9 316.6 122.9 291.4 313.2 159.8 131.2 309.3 171.4 122.4 385.2 506.9 321.6 131.5 1048.3 1396.3 914.1 833.9 802.7 931.9 852.4 977.9 1104.0 1770.4 1356.8 1420.1 457.7 1428.7 735.7 1032.2 774.7 907.6 1962.5 1505.4 1890.2 468.1 1454.0 799.3 854.7 1597.9 1226.2 826.4 771.9 1244.8 763.3 1491.8 1510.3 1055.1 1351.6 784.4 831.1 284.9 1294.2 1092.6 865.0 704.8 789.1 1068.6 952.6 802.1 691.1 682.2 1249.8 939.1 481.2 934.2 883.0 585.6 1273.8 679.4 651.5 625.1 976.1 930.2 649.9 603.8 2010.9 276.0 425.7 921.2 1000.8 999.3 1045.7 318.5 1639.1 408.1 463.4 1377.5 755.2 469.1 493.1 497.9 1905.9 412.2 477.7 488.1 157.1 658.5 1076.3 727.7 682.0 2945.6 110.2 113.4 118.1 129.6 112.7 123.9 128.9 119.1 125.9 122.9 131.2 131.5 212.3 115.4 239.6 0.0 139.7 1342.5 678.5 1913.6 173.0 113.5 191.0 183.4 6.8 104.4 799.6 73.5 116.7 345.6 185.8 100.5 152.6 295.4 32.4 120.7 171.6 286.1 116.1 139.6 0.0 231.4 370.5 299.2 129.5 165.0 149.1 237.5 154.2 63.8 212.1 106.0 0.0 117.3 767.0 160.4 1330.1 42.0 160.9 206.7 725.7 0.0 133.3 120.7 119.4 0.0 0.0 313.9 123.3 109.1 134.7 342.8 151.8 174.0 446.1 119.4 151.2 374.4 871.4 71.5 102.8 154.0 1233.4 636.9 224.2 197.1 135.9 474.6 EIF4E2 "4EHP, EIF4EL3, IF4e" ENSG00000135930 "Eukaryotic translation initiation factor 4E family member 2" O60573 2 232550674-232583644 "Predicted intracellular proteins" "Protein biosynthesis, RNA-mediated gene silencing, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 302.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019253, HPA077074" Enhanced Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Cytosol "HPA019253: AB_1848092, HPA077074: " "unprognostic (3.44e-2)" "unprognostic (2.70e-1)" "unprognostic (1.30e-1)" "unprognostic (3.83e-2)" "unprognostic (1.63e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.38e-4)" "unprognostic (1.42e-1)" "unprognostic (5.62e-3)" "unprognostic (1.42e-2)" "unprognostic (1.31e-1)" "unprognostic (1.21e-2)" "unprognostic (1.36e-2)" "unprognostic (7.74e-2)" "unprognostic (3.34e-3)" "unprognostic (1.88e-1)" "unprognostic (9.38e-2)" 40.8 35.9 27.8 52.4 29.0 58.3 43.0 29.2 34.3 35.4 26.9 67.4 50.6 41.6 36.9 51.9 33.2 42.8 38.3 28.1 29.2 63.9 93.2 45.2 49.2 30.4 28.7 33.6 40.8 36.2 24.5 56.9 31.5 34.8 77.2 34.4 38.8 31.8 153.1 50.2 52.5 56.1 27.1 42.5 51.1 42.2 29.5 41.9 36.2 62.5 61.9 47.3 34.3 31.1 104.9 99.5 108.7 79.3 83.4 110.2 161.9 144.9 88.3 101.9 107.8 109.8 100.3 109.0 39.0 151.6 116.7 88.6 128.2 131.2 128.9 98.6 122.0 146.6 97.4 149.9 98.8 213.0 130.7 103.1 98.1 105.5 78.5 102.8 172.1 53.0 139.0 34.7 118.7 201.4 83.1 171.0 174.3 124.1 83.5 73.2 231.7 72.3 209.6 133.2 98.7 135.5 77.0 86.6 95.3 117.2 81.3 145.3 148.6 88.3 114.9 96.6 106.1 67.3 71.0 139.8 100.0 109.4 78.9 299.2 205.7 194.4 63.6 220.0 51.4 62.2 65.8 67.7 179.3 60.5 55.1 56.1 132.1 70.7 205.9 70.9 114.7 155.5 27.8 29.0 29.2 34.3 28.1 29.2 30.4 28.7 31.5 27.1 29.5 31.1 37.2 41.7 57.3 11.8 40.1 38.0 78.2 127.4 31.3 19.8 41.5 49.3 36.9 65.8 85.4 35.0 18.8 142.0 53.6 109.1 74.3 164.5 129.6 45.6 63.1 46.9 66.0 50.7 20.0 151.5 204.3 60.2 48.9 68.6 43.7 47.2 50.0 119.9 125.4 20.2 19.3 111.3 120.1 90.8 87.5 302.4 38.2 72.6 30.2 10.3 135.8 29.3 51.5 12.1 29.7 159.8 109.3 38.7 51.8 96.8 139.1 170.8 58.8 22.3 26.3 38.8 118.5 68.4 56.0 59.7 51.1 182.5 42.7 92.3 87.9 120.4 EIF4G2 "DAP5, NAT1, p97" ENSG00000110321 "Eukaryotic translation initiation factor 4 gamma 2" P78344 11 10797050-10808940 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005163, HPA006773, HPA016965" Approved Enhanced Cytosol NA NA 48000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB005163: AB_638994, HPA006773: AB_1848099, HPA016965: AB_1848100" "unprognostic (1.10e-2)" "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (9.92e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (6.18e-5)" "unprognostic (1.25e-1)" "unprognostic (7.84e-3)" "unprognostic (5.42e-2)" "unprognostic (7.07e-2)" "unprognostic (2.63e-1)" "prognostic favorable (1.67e-4)" "unprognostic (1.02e-2)" "unprognostic (2.08e-1)" "unprognostic (6.16e-2)" "unprognostic (2.74e-1)" 307.1 259.9 177.4 278.4 178.0 516.4 213.7 182.9 197.9 281.1 260.2 329.2 217.0 310.5 310.1 372.0 265.0 290.0 377.9 165.0 195.9 321.8 288.7 312.8 286.6 190.0 226.5 247.1 259.6 368.6 160.2 406.4 196.9 276.2 318.6 258.5 231.1 305.5 456.4 299.5 216.3 395.9 186.5 249.5 245.4 226.4 193.0 384.8 349.7 372.4 369.3 430.0 203.0 191.1 933.5 715.1 958.4 527.9 668.2 712.0 668.4 848.9 841.7 713.1 483.6 790.1 1064.3 525.7 474.1 1029.4 545.2 537.8 1048.1 781.0 970.8 820.1 489.0 676.3 427.7 607.2 580.2 1041.8 545.9 582.3 601.0 444.6 577.3 657.1 830.2 483.5 527.8 570.5 935.1 481.8 691.7 377.9 702.1 646.8 756.0 690.3 563.8 336.1 630.7 1328.3 357.9 584.6 966.5 658.7 516.7 640.7 561.1 474.5 805.5 916.1 614.8 793.4 711.4 281.5 841.5 766.9 531.5 600.2 998.7 343.1 331.3 498.6 212.1 382.2 277.0 251.3 237.3 250.1 304.6 212.9 205.8 212.9 244.6 262.4 422.3 162.3 295.9 767.1 177.4 178.0 182.9 197.9 165.0 195.9 190.0 226.5 196.9 186.5 193.0 191.1 306.7 323.7 284.4 48.6 273.6 633.2 372.0 213.4 285.1 128.1 236.0 196.0 382.6 198.8 243.4 147.1 123.0 321.8 289.0 422.3 244.6 325.2 163.7 213.4 247.1 302.9 247.8 169.1 48.1 368.1 373.7 250.1 263.5 269.3 199.5 271.3 209.9 209.0 272.2 164.9 53.8 279.7 191.2 240.1 417.9 152.0 208.8 312.7 250.8 54.4 279.7 197.3 224.6 36.7 53.3 582.5 260.6 240.7 262.0 307.1 205.6 329.5 225.3 142.8 131.5 328.1 363.1 203.6 197.6 320.3 630.1 1056.1 267.7 281.2 289.0 518.3 ELAVL1 "Hua, HUR, MelG" ENSG00000066044 "ELAV like RNA binding protein 1" Q15717 19 7958573-8005659 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 227.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005256, HPA046298" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 230000 "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli, Cytosol" "CAB005256: AB_2096342, HPA046298: AB_2679618" "unprognostic (1.19e-1)" "unprognostic (9.66e-3)" "unprognostic (2.46e-2)" "unprognostic (3.98e-1)" "unprognostic (1.04e-1)" "unprognostic (6.37e-3)" "unprognostic (1.81e-2)" "unprognostic (8.44e-2)" "unprognostic (3.75e-2)" "prognostic favorable (4.93e-4)" "unprognostic (2.09e-1)" "unprognostic (1.59e-2)" "unprognostic (7.23e-2)" "unprognostic (6.14e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-2)" 27.5 27.7 14.5 33.1 15.6 27.8 25.0 16.0 15.7 29.4 19.5 27.9 25.2 31.6 25.9 30.0 34.3 22.4 34.0 15.3 15.9 24.8 29.0 24.2 40.2 13.7 15.6 31.8 28.4 37.5 21.4 32.7 13.8 26.9 27.2 19.0 29.6 29.4 37.7 24.9 25.1 35.9 16.2 30.1 24.6 46.1 15.1 52.7 27.9 32.2 44.1 37.4 25.2 16.6 127.5 84.1 137.9 104.5 52.9 52.7 76.5 89.5 78.4 136.9 106.3 122.4 73.2 153.2 125.5 104.0 76.9 86.0 155.2 107.9 114.8 134.9 131.8 135.5 58.9 115.7 77.4 129.9 103.1 65.8 63.6 95.7 57.7 64.8 106.2 115.6 140.7 112.6 95.7 95.8 215.3 103.7 122.1 96.4 101.6 239.0 89.6 100.9 87.5 93.9 98.0 70.8 88.9 89.1 71.7 82.6 101.8 101.4 79.7 127.3 87.3 119.2 161.8 109.8 114.7 161.9 71.3 154.2 112.2 29.9 19.7 37.2 16.4 17.2 17.0 20.8 24.0 26.3 25.0 27.7 21.8 16.6 5.3 33.1 22.1 12.5 20.9 16.3 14.5 15.6 16.0 15.7 15.3 15.9 13.7 15.6 13.8 16.2 15.1 16.6 45.7 25.6 23.1 18.6 56.0 72.4 79.5 29.0 51.2 47.2 54.9 37.2 31.3 30.0 20.7 47.8 56.3 86.8 48.1 32.9 66.5 37.1 227.7 41.6 46.5 52.2 42.0 95.7 20.3 33.8 102.3 53.1 40.2 47.2 21.0 59.5 47.2 89.2 64.2 60.6 21.5 52.9 18.3 57.5 79.2 164.1 50.4 47.3 51.6 23.4 43.9 43.4 57.7 33.7 26.9 35.3 45.7 56.8 88.7 98.2 38.3 65.8 27.3 55.7 52.6 45.5 71.0 164.7 61.2 72.0 71.0 74.8 50.9 44.7 60.2 84.6 EMC4 "FLJ90746, MGC24415, PIG17, TMEM85" ENSG00000128463 "ER membrane protein complex subunit 4" Q5J8M3 15 34225013-34230156 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053440 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA053440: AB_2682151" "unprognostic (8.99e-2)" "unprognostic (1.59e-1)" "unprognostic (7.68e-2)" "unprognostic (3.29e-2)" "unprognostic (9.23e-2)" "unprognostic (1.29e-3)" "unprognostic (3.25e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (1.78e-3)" "unprognostic (1.33e-1)" "unprognostic (2.20e-2)" "unprognostic (2.52e-1)" "unprognostic (5.42e-2)" "unprognostic (4.20e-2)" "unprognostic (2.96e-1)" "unprognostic (1.97e-2)" 76.1 68.1 83.8 48.8 86.5 58.7 68.4 90.3 103.7 69.3 92.0 69.1 55.1 67.0 102.9 78.3 67.8 52.3 86.4 87.6 88.8 67.9 91.3 57.3 55.4 87.2 85.2 66.2 90.7 83.0 60.3 59.2 88.4 62.3 58.2 65.4 79.0 63.7 214.4 63.9 57.1 58.8 86.9 49.1 69.8 49.4 85.7 58.1 60.6 136.7 54.2 59.2 71.4 95.2 123.1 248.2 103.9 135.1 133.2 119.6 95.0 137.7 156.9 166.0 143.4 162.0 106.1 48.5 177.7 160.0 145.6 229.4 107.0 135.3 118.7 148.3 103.7 91.9 219.4 154.8 161.0 139.8 87.8 121.4 126.3 121.4 136.0 118.1 139.8 144.6 117.0 186.6 147.1 137.9 109.9 149.9 116.9 165.0 163.5 102.0 94.7 138.3 161.0 186.9 137.1 166.4 101.7 148.3 77.6 74.8 99.3 164.7 106.5 151.3 103.8 131.8 142.7 162.8 251.5 122.0 184.5 164.1 131.1 256.5 158.6 176.9 154.5 173.9 170.0 237.2 170.6 185.8 162.6 187.7 172.2 168.8 88.5 197.8 200.2 166.6 216.1 277.6 83.8 86.5 90.3 103.7 87.6 88.8 87.2 85.2 88.4 86.9 85.7 95.2 75.3 54.5 67.7 8.8 67.9 91.5 103.7 206.5 55.8 35.8 83.7 104.1 58.7 58.6 132.4 66.2 18.8 150.6 62.5 39.5 125.2 180.3 121.8 67.6 55.1 86.1 52.0 38.7 14.1 172.3 173.6 87.8 36.7 69.1 88.0 63.2 64.2 78.6 113.7 18.5 15.4 62.8 166.8 48.5 73.2 27.4 100.6 56.5 101.4 13.1 87.9 98.4 76.2 15.1 16.9 184.0 65.4 90.7 117.9 89.6 71.8 117.5 133.3 42.8 85.5 81.4 123.2 169.7 91.9 60.2 110.0 141.7 68.8 69.7 66.4 125.4 EMC6 "MGC2963, RAB5IFL, TMEM93" ENSG00000127774 "ER membrane protein complex subunit 6" Q9BV81 17 3668812-3669668 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 185.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062681 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Centrosome Nucleoplasm "HPA062681: AB_2684831" "unprognostic (2.21e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.21e-2)" "unprognostic (1.62e-1)" "unprognostic (1.63e-1)" "unprognostic (6.20e-3)" "unprognostic (4.03e-2)" "prognostic unfavorable (9.39e-5)" "unprognostic (1.86e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-2)" "unprognostic (7.58e-3)" "unprognostic (4.17e-2)" "unprognostic (1.94e-1)" "unprognostic (6.37e-2)" "unprognostic (3.27e-1)" "unprognostic (6.32e-2)" 35.6 58.2 35.1 14.7 36.0 30.3 31.4 38.9 40.2 24.7 40.1 40.8 20.0 29.1 11.3 49.3 27.0 5.2 91.0 34.8 37.2 53.2 75.8 29.2 13.3 36.2 35.3 23.4 44.3 18.5 27.7 13.5 35.9 33.0 10.3 17.2 35.5 10.6 185.0 36.9 35.3 9.0 38.5 37.8 47.4 63.3 37.3 15.5 29.6 60.7 12.6 32.8 30.4 37.8 92.8 88.6 38.1 40.1 26.9 21.4 73.2 64.7 31.4 51.7 47.5 54.1 33.8 57.6 91.6 30.3 45.9 87.2 44.5 45.6 37.2 56.0 166.2 41.9 65.4 76.2 38.7 29.3 41.6 27.1 50.6 47.8 33.2 40.9 39.8 68.0 53.4 40.6 38.6 56.2 60.5 86.2 55.0 55.9 99.1 55.7 35.5 55.3 74.2 25.9 31.3 56.7 53.1 41.2 75.6 37.8 48.0 31.1 44.2 43.3 54.4 65.9 96.5 39.5 47.1 38.4 67.7 38.0 53.3 91.6 83.1 87.1 66.1 83.8 61.1 74.6 73.6 73.4 72.7 72.0 75.2 68.5 62.8 56.5 60.7 114.3 92.5 87.4 35.1 36.0 38.9 40.2 34.8 37.2 36.2 35.3 35.9 38.5 37.3 37.8 40.1 16.0 25.9 9.4 60.3 89.0 127.1 144.2 42.1 41.8 82.9 87.8 0.2 82.9 74.8 58.8 35.5 118.4 68.1 55.7 166.3 126.2 252.2 90.0 42.7 56.6 51.4 46.7 7.4 142.8 148.6 40.8 48.4 58.0 55.2 59.8 47.5 148.7 102.5 33.7 8.4 74.7 105.8 57.1 49.6 176.1 38.5 56.6 67.6 3.7 83.3 125.9 77.2 5.5 17.9 164.8 71.6 34.3 81.9 179.9 84.6 203.8 82.2 52.9 39.5 43.3 111.7 151.0 91.6 81.1 101.9 129.0 52.7 65.0 72.6 169.5 EMC7 "C11orf3, C15orf24" ENSG00000134153 "ER membrane protein complex subunit 7" Q9NPA0 15 34084017-34101862 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010029 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA010029: AB_1078335" "unprognostic (2.16e-1)" "unprognostic (8.16e-3)" "unprognostic (5.28e-2)" "prognostic favorable (4.68e-5)" "unprognostic (7.75e-2)" "prognostic unfavorable (9.25e-5)" "unprognostic (1.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.18e-1)" "unprognostic (5.65e-3)" "unprognostic (4.67e-2)" "unprognostic (3.17e-1)" "unprognostic (1.36e-1)" "unprognostic (3.31e-1)" "unprognostic (2.58e-1)" "unprognostic (2.49e-2)" "unprognostic (2.47e-3)" 65.4 86.5 74.2 48.3 78.2 75.2 58.5 82.6 92.9 47.2 91.4 61.3 52.1 49.6 104.4 47.6 45.9 50.4 70.4 74.1 85.7 90.7 103.8 54.4 43.8 78.5 79.2 43.1 79.1 93.2 54.7 77.3 79.7 62.2 64.8 67.2 59.9 57.0 91.0 56.0 46.8 58.8 82.1 42.5 57.7 76.9 79.6 40.1 71.0 70.9 46.2 63.0 44.0 87.0 68.1 185.7 62.2 84.2 249.3 143.3 69.3 190.4 199.3 174.8 181.0 170.6 79.7 40.4 187.4 189.5 181.3 128.9 94.7 96.3 128.5 99.7 96.5 99.4 273.6 147.3 229.1 101.2 135.0 155.1 181.5 125.0 178.7 117.3 110.3 75.9 99.5 259.9 170.7 79.8 54.5 115.2 58.1 157.2 122.3 69.5 76.2 140.3 187.3 119.1 107.2 78.2 114.0 151.8 97.7 75.5 110.0 161.2 94.9 185.8 71.6 123.7 144.4 172.4 219.7 86.2 187.8 153.3 154.8 316.0 161.1 178.1 139.7 184.2 136.9 137.0 138.6 144.0 150.6 102.9 100.4 124.1 143.8 122.7 206.2 242.6 195.8 196.4 74.2 78.2 82.6 92.9 74.1 85.7 78.5 79.2 79.7 82.1 79.6 87.0 65.5 28.9 36.1 20.2 51.7 86.9 56.8 194.6 40.9 58.6 44.0 50.3 92.9 54.3 117.9 103.0 45.9 127.5 92.1 56.5 39.2 124.4 117.3 52.4 66.2 67.3 45.6 48.0 15.5 172.4 153.4 90.1 32.6 52.6 45.1 40.2 60.3 78.6 112.6 30.3 17.8 57.6 146.5 65.2 60.1 81.6 90.1 61.2 103.2 12.2 70.9 112.4 40.2 17.6 27.7 137.9 63.0 104.2 97.1 61.3 72.5 90.8 94.5 62.9 118.3 65.4 136.5 257.9 57.4 43.1 86.4 160.1 65.8 100.4 61.3 55.2 EMG1 "C2F, Grcc2f, NEP1" ENSG00000126749 "EMG1 N1-specific pseudouridine methyltransferase" Q92979 12 6970913-6997428 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, RNA-binding, rRNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039304, HPA039666" Supported Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA039304: AB_2676432, HPA039666: AB_10672891" "unprognostic (1.23e-1)" "unprognostic (1.17e-1)" "unprognostic (6.77e-2)" "unprognostic (1.35e-2)" "unprognostic (2.11e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.69e-4)" "unprognostic (2.70e-1)" "unprognostic (1.03e-1)" "unprognostic (2.12e-1)" "unprognostic (9.03e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (2.83e-6)" "unprognostic (2.13e-1)" "unprognostic (2.34e-1)" "unprognostic (6.75e-2)" "unprognostic (1.62e-1)" 16.8 18.0 13.0 15.2 14.2 12.6 17.3 14.4 20.2 14.9 15.9 14.0 11.1 14.5 13.6 20.2 16.1 4.6 22.6 13.2 14.1 23.2 22.8 15.9 13.4 14.4 14.2 13.9 13.6 9.4 12.8 8.6 14.5 15.7 9.7 9.3 13.6 6.1 21.2 17.4 14.0 7.4 14.3 18.1 14.6 9.9 14.0 12.3 15.6 12.8 12.8 16.1 14.1 15.3 55.5 53.7 20.5 25.2 15.8 11.5 84.7 40.1 17.9 31.2 21.2 106.4 57.6 55.4 14.7 25.1 56.8 39.8 18.9 46.1 35.2 40.1 30.6 76.8 51.7 99.6 20.3 79.0 47.8 18.5 27.2 45.5 51.8 16.2 13.9 38.6 38.6 12.1 29.8 65.3 41.4 48.3 169.6 45.4 28.0 56.3 41.2 44.0 20.0 68.8 11.9 35.7 42.2 43.9 41.4 57.5 12.0 57.8 29.2 32.4 42.6 26.8 92.9 14.6 17.9 97.7 34.8 33.7 52.8 15.5 44.1 22.3 60.7 66.4 63.3 85.3 63.6 67.6 51.2 88.0 74.4 69.1 6.2 60.9 86.4 55.8 68.1 81.3 13.0 14.2 14.4 20.2 13.2 14.1 14.4 14.2 14.5 14.3 14.0 15.3 30.1 16.0 41.3 1.3 34.0 36.6 92.2 79.1 25.0 14.7 29.0 36.8 0.0 24.3 60.9 42.3 8.4 107.3 22.8 18.1 49.0 75.3 9.6 23.1 24.8 32.3 9.6 16.0 1.3 66.8 121.0 31.8 11.7 22.7 60.9 27.7 23.2 35.9 65.4 16.8 1.4 25.7 71.2 25.0 29.3 15.5 37.9 27.7 28.4 1.9 45.1 24.5 43.3 2.0 2.7 75.7 19.8 25.9 17.3 69.0 25.1 81.1 54.0 16.0 39.5 29.2 86.5 28.9 59.7 28.4 39.9 74.3 30.6 46.4 35.7 75.8 ENY2 "DC6, FLJ20480, Sus1" ENSG00000120533 "ENY2 transcription and export complex 2 subunit" Q9NPA8 8 109334324-109345954 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Transcription, Transcription regulation, Translocation, Transport" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024648 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Mitochondria" "HPA024648: AB_2100208" "unprognostic (2.10e-3)" "unprognostic (1.96e-1)" "unprognostic (2.18e-1)" "unprognostic (7.85e-2)" "unprognostic (7.70e-2)" "unprognostic (7.45e-3)" "unprognostic (1.48e-2)" "unprognostic (6.65e-2)" "unprognostic (2.54e-1)" "unprognostic (1.21e-2)" "unprognostic (1.47e-1)" "unprognostic (8.86e-3)" "prognostic unfavorable (7.17e-6)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "unprognostic (8.84e-2)" "unprognostic (2.66e-1)" 54.4 55.5 28.1 44.7 29.1 87.6 57.0 29.3 45.3 44.2 32.9 59.5 54.5 37.9 53.8 48.2 36.1 29.9 64.2 29.1 32.2 74.4 101.3 40.4 49.6 31.5 30.5 29.5 44.9 47.2 34.4 41.3 30.1 39.0 55.1 24.5 43.7 36.0 71.7 34.7 47.9 44.1 29.8 47.7 47.9 34.8 29.7 60.3 38.0 68.5 53.8 48.4 38.9 30.9 180.3 145.9 213.6 97.1 79.5 101.0 61.4 140.0 89.9 141.2 177.2 109.0 109.1 115.3 127.9 110.9 63.6 89.7 96.8 99.5 171.7 184.1 113.9 223.5 106.7 227.4 85.4 78.3 133.5 77.5 66.7 92.5 87.3 102.2 215.1 111.5 216.5 63.7 162.7 289.9 235.9 175.5 156.1 207.1 140.3 148.4 93.2 144.5 192.5 134.7 128.9 137.5 87.7 109.3 127.2 117.0 138.6 132.3 146.9 94.1 158.9 97.8 144.7 107.9 125.6 222.2 95.2 128.3 112.7 65.6 102.5 93.5 28.9 112.8 36.7 41.4 39.0 35.6 93.8 27.3 31.9 35.8 56.8 42.4 121.8 80.3 42.3 74.5 28.1 29.1 29.3 45.3 29.1 32.2 31.5 30.5 30.1 29.8 29.7 30.9 231.3 70.5 93.8 16.3 135.0 185.6 196.3 305.7 159.9 63.8 149.2 192.7 170.6 138.7 184.6 145.3 123.0 263.3 157.0 171.5 381.5 214.3 173.3 146.4 134.7 226.3 154.2 160.1 22.7 200.0 284.5 161.0 88.7 144.8 91.8 99.3 142.5 371.1 276.8 45.4 23.9 245.1 225.9 230.3 265.7 111.0 148.2 205.0 158.3 17.8 260.9 112.4 126.7 19.6 27.6 251.2 237.1 112.5 147.2 230.3 264.5 546.1 125.0 139.9 78.9 163.9 262.9 208.7 130.4 151.0 174.6 167.3 132.4 143.9 209.1 208.0 ESD ENSG00000139684 "Esterase D" P10768 13 46771256-46797420 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 569.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039700 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039700: AB_10697553" "unprognostic (3.05e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (7.66e-2)" "unprognostic (1.75e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.73e-2)" "unprognostic (3.31e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (2.91e-2)" "unprognostic (2.71e-2)" "unprognostic (2.18e-1)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" 123.8 87.5 83.0 73.0 85.5 95.1 146.7 86.3 110.8 141.0 87.7 125.7 106.7 129.7 160.1 93.6 121.8 96.4 151.5 84.3 98.6 194.4 277.2 92.3 93.5 87.3 85.6 179.0 67.3 109.9 81.5 81.9 89.7 112.5 135.0 122.0 92.8 140.3 149.8 83.3 93.4 166.2 94.3 63.9 83.0 54.2 82.4 155.7 155.0 179.0 110.3 104.9 96.2 100.0 138.4 77.9 229.8 160.4 264.5 441.9 62.5 190.8 280.9 264.7 204.6 131.6 162.8 156.5 56.9 233.3 194.0 137.1 256.8 227.2 333.0 180.4 270.4 200.3 70.7 208.6 220.5 400.1 82.2 304.6 207.0 167.9 229.4 316.2 253.2 260.3 200.3 40.7 433.5 135.1 352.7 260.0 59.8 175.2 148.8 277.1 133.6 106.2 378.4 55.4 115.0 130.1 85.0 72.6 160.3 157.6 137.1 223.0 169.2 94.4 113.0 187.5 181.8 27.6 63.5 135.7 205.3 223.2 131.2 35.0 129.4 55.7 48.5 113.6 80.9 104.1 97.6 76.3 142.8 83.4 114.1 90.5 15.0 109.3 106.1 170.7 90.6 100.3 83.0 85.5 86.3 110.8 84.3 98.6 87.3 85.6 89.7 94.3 82.4 100.0 139.0 54.5 56.8 37.5 77.2 134.1 227.4 300.5 148.0 51.5 114.1 123.2 99.2 167.3 111.7 154.5 41.7 160.4 51.2 59.1 360.0 168.0 135.5 102.2 120.6 112.5 108.8 99.5 22.7 103.2 141.0 162.9 51.0 80.7 96.4 71.1 132.1 154.7 227.5 21.9 19.3 114.6 175.0 140.2 148.0 34.8 267.8 108.2 165.4 25.3 144.3 199.5 36.0 23.6 36.2 85.4 92.3 211.4 35.9 99.1 137.1 569.1 94.2 77.3 151.2 196.0 484.2 61.6 46.3 120.6 129.3 74.4 78.2 151.2 199.8 143.6 ESF1 "bA526K24.1, C20orf6" ENSG00000089048 "ESF1 nucleolar pre-rRNA processing protein homolog" Q9H501 20 13714322-13784919 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047083, HPA050396" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli" "HPA047083: AB_2679924, HPA050396: AB_2681111" "unprognostic (2.81e-1)" "unprognostic (1.54e-1)" "unprognostic (1.82e-1)" "unprognostic (1.31e-2)" "unprognostic (4.83e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (7.81e-9)" "unprognostic (2.52e-2)" "unprognostic (3.17e-2)" "unprognostic (1.78e-1)" "unprognostic (4.17e-3)" "unprognostic (3.91e-2)" "unprognostic (7.34e-2)" "unprognostic (2.16e-2)" "unprognostic (2.02e-1)" "unprognostic (1.60e-2)" "unprognostic (1.57e-1)" 12.0 9.6 11.2 9.6 12.4 7.9 10.8 11.5 13.3 8.6 8.7 8.3 7.5 10.2 10.3 9.1 6.9 8.5 9.5 9.8 12.4 9.7 13.9 6.6 10.8 12.8 12.3 12.5 6.5 10.0 5.3 11.3 14.2 9.5 9.8 9.0 6.2 7.3 12.6 10.8 6.8 8.8 12.8 9.9 7.8 14.1 12.6 9.7 10.5 12.2 9.7 12.3 7.1 13.4 30.4 24.3 24.1 13.0 18.8 23.3 14.9 28.9 18.5 21.5 19.4 26.0 29.2 38.4 15.1 14.5 40.2 45.9 36.0 30.3 41.4 11.1 18.1 49.5 10.2 64.2 25.4 59.4 13.2 18.7 23.0 33.1 28.2 16.0 17.0 18.7 70.9 17.9 27.1 22.6 46.7 39.8 25.9 27.0 17.1 30.6 61.1 30.4 16.7 22.3 25.9 16.2 23.8 41.8 42.4 22.1 20.5 27.3 23.2 36.2 24.2 25.7 59.1 17.9 43.4 45.7 14.7 27.2 33.2 2.7 8.7 2.7 10.5 11.1 12.3 18.2 12.2 11.6 8.9 17.4 14.9 13.8 0.5 15.1 14.0 19.3 10.0 4.6 11.2 12.4 11.5 13.3 9.8 12.4 12.8 12.3 14.2 12.8 12.6 13.4 71.5 22.4 45.0 36.6 60.4 61.8 63.8 50.5 44.3 92.8 31.4 53.2 61.7 50.1 47.6 33.1 45.9 47.8 55.3 53.8 33.2 55.0 80.5 35.3 61.4 50.8 48.5 34.5 56.2 42.1 39.2 48.5 32.6 34.0 26.0 55.4 45.0 51.5 45.1 95.9 59.7 49.7 28.5 35.3 22.4 30.2 65.3 35.3 26.6 34.7 57.6 58.0 33.0 53.8 63.6 56.0 48.8 73.7 26.8 62.8 47.6 38.4 34.6 81.9 32.9 117.0 78.0 210.4 175.5 31.5 53.6 41.5 40.8 71.9 61.5 42.2 ETV3L FLJ16478 ENSG00000253831 "ETS variant transcription factor 3 like" Q6ZN32 1 157092043-157112412 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;choroid plexus: 1.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 1.3;Breast myoepithelial cells: 2.0;Langerhans cells: 3.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "hypothalamus: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "HDLM-2: 36.2" "Not detected" "Not detected" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (7.39e-4)" "unprognostic (1.53e-1)" "unprognostic (3.22e-2)" "unprognostic (1.79e-5)" "unprognostic (2.25e-1)" "unprognostic (5.91e-2)" "unprognostic (1.57e-2)" "unprognostic (3.09e-4)" "unprognostic (1.88e-1)" "unprognostic (5.37e-2)" "unprognostic (3.37e-1)" 0.0 0.0 0.1 0.3 0.3 0.0 0.8 0.0 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.2 1.8 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.3 2.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 EVI5 NB4S ENSG00000067208 "Ecotropic viral integration site 5" O60447 1 92508696-92792404 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027339 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" Vesicles "HPA027339: AB_1848308" "unprognostic (1.23e-1)" "unprognostic (2.84e-1)" "unprognostic (4.29e-3)" "unprognostic (1.65e-1)" "unprognostic (4.94e-2)" "unprognostic (1.06e-1)" "unprognostic (5.13e-3)" "unprognostic (7.43e-2)" "unprognostic (1.12e-1)" "unprognostic (9.11e-2)" "unprognostic (9.04e-3)" "unprognostic (2.25e-1)" "unprognostic (6.15e-2)" "unprognostic (8.30e-2)" "unprognostic (5.40e-1)" "unprognostic (6.38e-2)" "unprognostic (2.35e-2)" 5.7 8.1 5.9 4.5 8.3 2.7 4.4 8.5 5.8 5.9 8.2 4.8 4.3 6.4 4.6 4.0 5.1 5.8 7.1 4.2 7.7 5.0 16.4 7.1 3.2 8.1 6.2 3.8 3.8 7.9 3.9 12.1 6.8 5.3 5.5 4.9 4.5 5.6 2.9 5.0 4.0 7.1 8.6 4.5 6.4 9.6 6.3 1.3 6.6 3.6 3.3 5.5 3.8 10.9 5.4 5.9 9.1 8.9 14.5 18.2 8.6 12.2 18.5 8.2 9.4 10.4 1.4 2.4 16.8 14.0 15.2 6.1 8.6 9.0 14.6 0.2 3.3 4.3 5.6 6.2 14.2 3.1 4.8 11.5 7.2 14.2 8.5 23.9 17.9 0.2 7.7 3.8 13.9 2.7 0.3 3.6 2.6 3.5 4.8 2.2 21.7 3.2 6.3 15.5 3.4 7.0 14.4 7.4 16.6 9.8 3.6 7.1 11.8 9.1 6.6 12.2 8.1 5.5 3.4 3.8 6.0 5.0 7.6 0.9 2.7 2.8 0.1 1.9 0.0 1.2 0.1 0.0 1.3 1.2 0.0 0.0 3.4 0.1 2.9 0.8 0.0 0.4 5.9 8.3 8.5 5.8 4.2 7.7 8.1 6.2 6.8 8.6 6.3 10.9 27.2 60.9 29.9 91.4 18.7 43.5 29.3 23.0 18.2 24.5 20.5 17.7 51.8 22.8 32.3 16.5 25.0 48.4 7.5 22.9 17.6 27.9 3.0 67.8 39.4 31.2 22.1 11.4 158.4 29.9 26.0 42.5 42.3 26.2 13.3 21.9 43.2 52.4 32.2 30.3 149.3 27.0 14.2 54.0 27.0 5.8 28.3 45.1 26.6 114.3 48.9 28.5 5.2 112.6 199.6 68.4 19.3 54.2 28.8 28.1 21.8 20.1 46.9 25.4 13.1 51.4 56.4 37.4 42.4 21.2 50.0 65.5 5.5 60.9 20.0 32.1 EWSR1 EWS ENSG00000182944 "EWS RNA binding protein 1" Q01844 22 29268009-29300525 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Calmodulin-binding, Repressor, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004230, HPA051771, HPA062953" Enhanced Enhanced "Nucleoplasm,Nucleoli rim" No No 59000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli rim" "CAB004230: AB_675526, HPA051771: AB_2681602, HPA062953: AB_2684910" "unprognostic (1.96e-1)" "unprognostic (6.39e-3)" "unprognostic (1.32e-1)" "unprognostic (3.93e-2)" "unprognostic (3.59e-1)" "unprognostic (3.15e-2)" "prognostic unfavorable (1.27e-6)" "unprognostic (1.33e-1)" "unprognostic (1.09e-2)" "unprognostic (2.71e-2)" "unprognostic (7.04e-2)" "unprognostic (9.30e-2)" "prognostic unfavorable (1.21e-5)" "unprognostic (7.33e-3)" "unprognostic (1.79e-1)" "unprognostic (3.67e-2)" "unprognostic (1.50e-3)" 84.8 102.2 63.2 93.2 64.7 172.3 80.3 70.3 69.5 87.9 61.2 90.5 88.0 105.1 61.9 99.0 86.0 56.1 101.7 64.7 63.7 88.0 85.0 76.8 120.1 67.4 64.7 86.8 79.1 98.0 64.1 70.2 63.6 78.4 84.4 111.2 76.5 77.3 140.0 88.0 92.6 86.9 59.7 101.0 84.3 135.5 63.9 183.0 77.2 79.9 126.8 88.1 86.2 71.8 307.7 239.7 327.6 249.1 166.0 136.0 218.2 188.1 301.3 309.9 264.5 270.3 154.5 428.0 114.1 294.3 234.9 238.9 471.5 392.6 313.7 287.5 341.6 323.9 218.8 262.7 246.5 499.5 219.3 211.1 162.5 259.1 413.0 152.2 244.2 201.1 248.3 186.0 233.8 310.6 505.9 185.8 221.1 261.4 182.8 348.1 317.2 253.3 288.0 328.2 261.4 247.7 236.3 258.5 195.9 216.2 170.9 261.0 246.3 184.4 198.2 115.1 272.3 236.2 205.5 387.4 169.9 220.6 224.4 203.9 201.1 182.6 195.2 283.5 199.5 169.4 181.3 194.4 227.5 191.3 175.8 170.9 148.1 216.9 293.0 122.0 244.0 314.2 63.2 64.7 70.3 69.5 64.7 63.7 67.4 64.7 63.6 59.7 63.9 71.8 77.5 102.5 106.8 68.6 130.8 69.5 145.2 153.2 108.1 72.4 63.8 46.6 68.0 87.2 127.2 64.4 75.0 141.0 91.3 92.4 66.5 121.7 165.4 96.3 88.1 88.3 80.9 102.0 55.8 107.6 133.5 85.4 117.2 115.2 121.0 88.5 71.7 71.7 99.3 82.4 60.8 110.9 136.3 69.7 94.0 32.7 61.5 91.9 81.8 47.8 110.9 72.8 122.6 49.8 67.6 116.5 106.4 62.1 156.6 97.4 79.4 72.6 128.9 84.9 52.6 93.1 141.4 209.6 107.5 105.5 58.5 152.4 121.4 84.9 110.2 115.1 EXOC3 "SEC6L1, Sec6p" ENSG00000180104 "Exocyst complex component 3" O60645 5 443175-471937 "Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 61.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037880 Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Mitochondria" "HPA037880: AB_2675716" "unprognostic (2.94e-1)" "unprognostic (4.74e-3)" "unprognostic (4.82e-3)" "unprognostic (4.10e-1)" "unprognostic (6.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.91e-3)" "unprognostic (1.91e-1)" "unprognostic (6.62e-2)" "unprognostic (3.26e-1)" "prognostic favorable (1.54e-4)" "unprognostic (6.54e-2)" "unprognostic (2.33e-1)" "unprognostic (5.02e-2)" "unprognostic (2.97e-1)" "unprognostic (1.82e-1)" "unprognostic (1.70e-1)" 27.1 22.0 16.7 20.3 19.1 24.3 25.5 20.9 18.7 27.0 18.5 38.1 20.8 29.1 10.7 36.4 25.6 19.3 28.6 19.0 19.0 22.7 21.8 22.3 23.6 18.5 18.4 26.1 31.7 22.1 26.0 18.5 19.8 24.6 14.4 8.0 26.7 20.3 78.8 34.4 27.0 19.0 16.6 26.5 32.9 35.6 18.2 22.9 25.0 41.2 20.1 31.4 27.6 20.3 33.5 55.3 18.2 40.9 30.6 26.3 45.2 29.1 29.9 28.6 34.5 28.0 48.0 28.4 44.2 36.6 35.3 37.2 14.7 25.2 20.9 105.8 25.7 30.6 114.0 21.3 28.6 46.0 73.9 26.8 18.4 32.1 28.0 30.0 32.5 18.3 23.6 18.1 22.5 39.7 33.2 54.8 15.1 20.5 33.0 27.0 20.9 36.5 24.1 41.4 18.2 23.2 72.5 40.5 28.8 17.7 54.8 52.5 24.5 28.3 34.6 22.0 23.8 30.3 23.6 20.2 29.8 55.1 26.2 10.4 10.5 61.0 11.2 12.4 9.8 6.0 8.8 9.1 6.6 6.4 11.1 10.2 14.8 19.4 9.1 4.8 12.4 7.1 16.7 19.1 20.9 18.7 19.0 19.0 18.5 18.4 19.8 16.6 18.2 20.3 15.5 22.4 29.1 15.0 14.1 42.8 16.3 18.6 20.5 14.0 18.1 16.5 31.4 14.3 21.1 14.7 35.5 25.3 15.6 28.9 27.4 27.3 31.8 16.4 16.2 17.1 5.4 14.7 12.6 30.2 24.2 16.6 23.4 17.0 22.9 27.7 13.9 16.9 24.0 63.9 11.2 20.3 18.3 26.9 23.8 65.3 20.2 24.6 26.6 10.3 25.2 17.0 13.4 10.6 16.7 26.4 23.1 17.0 18.6 18.0 25.5 23.1 29.3 20.2 19.7 19.1 24.8 33.9 29.7 29.4 53.8 34.1 22.7 21.1 23.5 24.6 EXOC7 "BLOM4, EXO70, Exo70p, KIAA1067, YJL085W" ENSG00000182473 "Exocyst complex component 7" Q9UPT5 17 76081016-76121576 "Human disease related genes, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022840, HPA022842" Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol "Vesicles, Plasma membrane" "HPA022840: AB_1848316, HPA022842: AB_1848317" "unprognostic (5.20e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (3.49e-2)" "unprognostic (2.37e-2)" "unprognostic (1.88e-1)" "unprognostic (1.30e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (7.39e-3)" "unprognostic (1.53e-2)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (1.05e-1)" "unprognostic (1.18e-1)" 40.4 31.4 36.0 32.7 37.0 53.2 31.2 31.4 36.7 39.3 34.1 40.1 32.5 40.1 33.1 52.3 52.3 35.4 47.2 36.8 35.5 31.9 30.2 35.9 32.7 35.4 34.3 49.6 41.1 61.2 41.0 35.3 36.5 48.1 27.9 24.7 50.6 43.1 43.0 37.0 34.7 43.5 31.9 32.4 30.3 24.9 36.4 43.5 43.0 41.4 32.3 44.3 30.1 34.8 65.6 79.4 71.9 58.5 66.6 47.0 74.5 58.9 77.6 103.9 74.7 67.5 43.0 33.7 42.0 103.0 65.6 52.7 43.9 57.1 69.0 29.3 59.1 55.8 64.0 72.3 46.4 62.9 55.7 66.1 44.3 80.5 39.2 73.5 116.9 59.8 38.1 33.7 65.6 59.8 102.1 27.8 37.8 49.5 83.4 54.0 123.3 34.6 59.7 133.6 38.9 91.4 66.5 48.6 44.6 68.8 79.7 51.0 77.5 111.3 66.3 74.1 65.8 46.0 18.2 31.2 66.4 28.0 59.0 55.1 41.1 66.1 35.5 57.4 24.4 26.7 26.9 30.4 28.9 26.9 27.7 23.9 46.2 36.4 79.7 12.3 32.0 44.9 36.0 37.0 31.4 36.7 36.8 35.5 35.4 34.3 36.5 31.9 36.4 34.8 31.0 19.2 35.0 36.6 37.7 19.8 40.1 40.8 31.3 87.6 30.2 28.8 7.5 28.6 41.4 40.5 143.9 51.5 37.5 47.6 33.2 38.3 22.4 35.1 25.8 27.1 48.9 48.6 26.2 37.1 29.0 31.6 27.0 34.4 41.1 65.0 30.7 27.0 37.7 67.3 31.1 43.8 54.9 29.6 21.3 52.2 37.3 26.9 24.9 15.0 36.8 52.1 56.7 44.2 35.0 44.6 41.4 38.4 15.7 41.5 62.8 35.3 43.7 108.8 46.0 27.8 49.5 32.1 16.6 20.3 19.9 71.1 35.8 56.6 29.8 44.8 EXOSC7 "EAP1, hRrp42p, KIAA0116, p8, RRP42, Rrp42p" ENSG00000075914 "Exosome component 7" Q15024 3 44975241-45036066 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036182, HPA057980" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA036182: AB_10673346, HPA057980: AB_2683571" "unprognostic (1.69e-2)" "unprognostic (3.92e-3)" "unprognostic (1.84e-3)" "unprognostic (4.97e-2)" "unprognostic (3.00e-3)" "unprognostic (2.16e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-2)" "unprognostic (2.96e-1)" "unprognostic (7.85e-2)" "unprognostic (1.20e-1)" "unprognostic (7.67e-3)" "prognostic favorable (2.69e-4)" "unprognostic (4.33e-1)" "unprognostic (7.30e-2)" "unprognostic (2.94e-1)" "unprognostic (1.20e-1)" 17.5 44.1 9.5 12.5 9.5 17.2 18.4 10.0 10.4 23.5 10.7 15.3 11.6 20.4 7.0 27.2 17.0 9.1 27.0 9.5 10.9 22.2 18.1 15.0 19.6 10.4 9.8 19.0 18.6 20.1 17.3 15.4 10.1 15.9 10.8 5.9 17.5 15.9 43.8 44.6 13.2 11.2 9.7 15.3 20.0 23.2 10.5 20.2 19.9 36.4 16.8 22.7 22.2 9.8 61.5 55.7 44.9 37.3 45.9 50.0 40.5 26.2 42.2 56.0 57.7 93.3 47.8 77.4 40.3 45.6 42.6 33.9 55.9 72.2 46.0 52.3 49.2 67.5 64.5 91.5 88.7 95.3 26.5 44.1 45.6 61.2 123.6 36.5 54.8 84.9 107.4 37.8 40.3 63.2 68.6 167.9 54.3 55.2 78.4 33.8 41.7 117.7 51.0 85.5 20.9 31.4 37.0 31.6 39.7 38.4 46.7 77.9 39.3 28.8 43.0 48.3 71.7 47.1 47.5 92.6 42.4 131.6 26.2 6.8 41.3 7.6 38.8 41.5 43.6 71.3 44.6 40.2 66.0 59.7 51.8 41.4 2.1 58.3 31.5 40.2 47.7 45.4 9.5 9.5 10.0 10.4 9.5 10.9 10.4 9.8 10.1 9.7 10.5 9.8 25.0 35.3 30.1 16.0 23.2 61.8 68.8 97.2 47.3 29.5 23.9 43.2 39.0 21.5 46.5 35.0 18.8 67.8 22.1 8.6 135.0 51.7 3.9 23.7 34.8 24.0 13.1 19.6 19.9 46.7 62.4 32.7 23.0 21.7 15.2 33.0 18.2 28.6 46.5 20.2 22.5 19.3 79.3 14.2 22.6 8.3 47.8 17.4 26.6 8.4 20.6 37.6 33.0 10.6 14.0 41.7 10.3 41.0 19.4 74.8 17.7 47.4 34.3 23.4 13.1 25.7 53.9 53.7 66.3 35.5 74.2 63.1 26.2 52.2 24.3 56.3 FAM122A "C9orf42, MGC17347" ENSG00000187866 "Family with sequence similarity 122A" Q96E09 9 68780065-68785566 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056646 Approved Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" Nucleoplasm "HPA056646: AB_2683202" "unprognostic (1.88e-2)" "unprognostic (7.62e-2)" "unprognostic (9.17e-2)" "unprognostic (1.48e-2)" "unprognostic (2.55e-2)" "unprognostic (1.16e-1)" "unprognostic (9.79e-2)" "unprognostic (1.45e-2)" "unprognostic (4.18e-1)" "unprognostic (8.49e-3)" "unprognostic (1.45e-2)" "unprognostic (4.58e-3)" "prognostic favorable (1.34e-5)" "unprognostic (9.35e-2)" "unprognostic (3.02e-2)" "unprognostic (2.72e-1)" "unprognostic (6.89e-2)" 9.9 9.3 4.6 5.8 4.9 5.3 9.7 8.2 6.3 9.7 15.0 7.9 4.4 9.3 6.7 8.3 8.5 5.6 9.0 5.4 5.4 9.7 9.9 6.8 7.4 5.1 5.4 10.5 8.9 11.0 6.8 10.2 5.1 7.7 6.5 6.8 8.2 8.4 8.9 7.6 7.4 7.8 4.4 8.3 7.4 4.9 5.0 6.5 8.5 8.6 7.2 7.2 8.0 5.0 5.2 3.4 4.8 4.1 15.9 10.3 6.4 7.3 6.9 6.3 5.0 1.2 2.5 11.0 3.5 7.7 4.5 9.6 5.3 4.9 7.8 11.9 5.6 6.1 6.0 4.4 9.7 11.2 4.1 8.4 11.0 5.8 4.5 7.1 6.3 7.8 6.5 12.1 6.8 2.9 6.3 2.9 6.0 12.4 6.2 7.6 6.6 3.4 5.7 4.3 7.6 3.4 5.4 4.5 3.8 6.6 2.7 4.8 8.0 5.8 4.2 11.0 5.5 14.2 6.1 4.4 6.3 6.9 6.7 1.9 2.0 1.5 1.7 1.9 1.4 1.5 1.7 1.8 2.2 2.5 3.5 2.0 1.1 1.8 1.9 2.6 2.0 1.0 4.6 4.9 8.2 6.3 5.4 5.4 5.1 5.4 5.1 4.4 5.0 5.0 10.0 3.2 9.8 0.0 19.6 23.6 18.7 13.3 20.5 18.8 18.2 17.0 15.9 10.0 13.1 5.5 16.7 28.2 11.8 11.3 66.5 18.3 32.0 10.4 20.2 17.2 18.0 27.0 0.0 13.8 17.0 13.9 14.3 8.1 17.7 12.7 17.2 18.6 21.6 8.4 0.0 17.0 10.2 22.3 17.0 15.4 15.2 15.0 14.2 0.0 16.8 38.3 24.7 0.0 0.0 12.9 15.8 17.0 18.3 11.9 11.1 27.2 23.0 19.8 46.0 18.8 43.9 52.4 21.3 19.5 23.7 30.6 16.8 23.1 15.3 17.8 FAM162A "C3orf28, E2IG5" ENSG00000114023 "Family with sequence similarity 162 member A" Q96A26 3 122384176-122412334 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 625.3;Distal tubular cells: 540.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035856, HPA075611" Approved Supported Mitochondria NA NA 19000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA035856: AB_10611965, HPA075611: " "unprognostic (1.17e-2)" "unprognostic (1.42e-1)" "unprognostic (5.64e-2)" "unprognostic (1.10e-1)" "unprognostic (3.99e-1)" "unprognostic (7.84e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (5.91e-3)" "unprognostic (8.74e-2)" "unprognostic (1.95e-2)" "unprognostic (7.91e-3)" "unprognostic (4.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.06e-1)" "unprognostic (4.10e-2)" "prognostic favorable (3.93e-4)" 49.0 105.7 54.8 31.3 60.2 39.9 43.9 57.3 82.2 84.5 57.1 145.9 56.1 49.5 59.4 207.6 49.7 46.2 174.2 57.1 58.5 107.6 200.3 32.0 32.9 55.9 57.2 84.3 133.9 116.6 51.0 17.6 55.6 74.6 149.0 83.5 59.8 49.2 141.0 89.8 56.3 44.6 56.6 31.7 93.2 43.6 58.8 34.7 44.1 142.6 42.7 76.9 131.5 55.6 132.0 27.7 40.4 75.6 72.1 66.4 20.7 52.9 46.8 49.0 123.9 69.4 58.7 142.1 89.2 18.2 40.3 89.8 73.5 128.1 130.0 74.0 55.1 115.6 44.0 125.8 47.4 114.0 39.6 77.3 65.5 46.7 97.9 164.3 66.0 137.7 79.2 55.6 71.1 52.0 116.9 137.9 59.5 294.9 144.4 69.5 57.8 186.9 144.3 314.9 60.1 48.1 39.4 92.4 114.3 59.9 57.9 55.7 47.0 48.4 34.6 28.7 55.6 108.8 39.9 144.8 143.3 109.7 22.8 9.9 25.8 75.7 58.3 68.2 86.9 75.3 79.5 74.0 84.6 68.1 85.1 88.6 8.5 50.6 75.9 70.4 80.4 38.8 54.8 60.2 57.3 82.2 57.1 58.5 55.9 57.2 55.6 56.6 58.8 55.6 55.7 28.9 46.0 41.1 68.2 128.1 155.3 625.3 82.0 31.5 80.6 109.5 338.4 84.4 188.6 130.6 47.9 51.4 47.9 477.5 540.0 148.2 102.5 82.0 30.1 49.8 106.9 47.7 33.0 177.6 47.8 78.7 84.6 79.2 85.7 59.3 44.6 280.4 92.7 38.7 30.4 374.3 240.1 66.7 108.9 33.1 134.5 61.2 104.9 7.5 108.9 79.7 45.3 22.1 21.6 141.6 313.2 148.6 61.2 121.4 186.2 466.2 95.5 29.9 105.2 83.2 315.3 146.4 68.3 315.1 132.8 47.2 66.0 121.1 358.4 210.9 FARSB "FARSLB, FRSB, PheHB" ENSG00000116120 "Phenylalanyl-tRNA synthetase subunit beta" Q9NSD9 2 222566899-222656092 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036677, HPA036678, HPA061398" Enhanced Supported Nucleoplasm,Cytosol NA NA 28000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA036677: AB_2675242, HPA036678: AB_10673504, HPA061398: AB_2684504" "unprognostic (9.95e-3)" "unprognostic (1.86e-3)" "unprognostic (7.02e-2)" "unprognostic (7.42e-3)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (6.45e-10)" "unprognostic (8.89e-3)" "unprognostic (4.51e-2)" "unprognostic (3.63e-2)" "unprognostic (5.25e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.36e-1)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.25e-4)" 12.8 10.9 9.5 7.6 10.0 8.0 12.8 10.4 11.3 13.1 6.5 14.7 9.1 13.5 6.5 20.7 11.9 3.9 16.7 10.2 10.7 11.8 14.1 9.4 7.4 9.6 9.4 14.3 15.6 8.0 13.2 5.0 10.8 11.2 11.1 10.0 10.4 6.1 31.9 14.9 10.8 8.1 8.4 9.7 13.9 13.5 9.9 7.7 9.7 13.2 8.3 13.1 13.7 9.4 31.1 17.8 20.7 27.2 18.0 26.3 31.0 31.0 19.2 29.4 23.9 45.3 16.6 15.3 22.7 22.6 24.7 25.8 39.7 34.7 43.0 22.8 20.7 35.1 18.9 28.8 27.9 51.9 14.0 17.6 27.0 33.9 51.2 10.5 28.3 26.4 53.5 30.3 36.1 28.9 31.2 29.2 26.6 37.0 22.0 30.2 49.4 49.8 24.5 19.9 33.4 11.2 12.9 22.4 27.6 24.7 20.9 21.3 15.8 25.5 21.1 37.8 38.5 14.8 15.5 54.5 20.8 34.0 27.2 0.5 7.6 1.2 9.6 9.4 14.3 15.1 12.8 11.9 14.4 12.7 16.4 14.2 0.9 17.4 11.3 7.2 12.5 13.7 9.5 10.0 10.4 11.3 10.2 10.7 9.6 9.4 10.8 8.4 9.9 9.4 10.2 6.4 6.4 21.2 25.2 12.4 19.5 32.7 19.4 17.9 16.3 18.0 28.6 5.7 18.5 22.0 4.2 37.0 7.5 18.1 35.2 24.7 57.5 17.3 15.8 13.3 20.9 24.2 50.2 30.4 43.3 18.0 32.6 18.6 5.1 21.8 7.5 17.8 27.4 3.3 56.7 19.9 20.3 10.1 9.7 73.1 15.2 11.8 7.2 26.2 11.3 13.2 15.5 38.7 38.2 22.8 11.3 19.9 27.3 18.1 9.9 31.0 16.8 19.5 6.6 17.6 34.4 67.4 33.7 28.8 14.2 22.2 16.9 24.3 45.8 14.3 FBXO4 FBX4 ENSG00000151876 "F-box protein 4" Q9UKT5 5 41925254-41941743 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003362 Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA003362: AB_2666918" "unprognostic (1.43e-1)" "unprognostic (2.10e-2)" "unprognostic (9.25e-3)" "unprognostic (2.65e-2)" "unprognostic (2.50e-1)" "unprognostic (7.32e-2)" "unprognostic (6.15e-2)" "unprognostic (1.48e-2)" "unprognostic (1.62e-3)" "unprognostic (5.42e-3)" "unprognostic (1.69e-1)" "unprognostic (5.42e-2)" "prognostic unfavorable (1.28e-4)" "unprognostic (8.57e-2)" "unprognostic (1.51e-1)" "unprognostic (5.39e-2)" "unprognostic (8.27e-2)" 10.0 7.5 2.3 6.8 2.8 8.4 12.4 3.0 3.6 8.8 2.2 6.8 7.9 6.2 15.8 6.3 8.3 6.6 5.3 2.4 2.9 7.4 11.2 6.6 11.6 2.5 2.5 7.3 11.8 7.0 4.4 6.0 2.8 8.3 8.0 4.9 7.3 8.1 4.1 7.0 7.0 5.9 2.8 9.3 8.0 8.3 2.5 11.1 12.7 4.9 12.5 6.3 5.5 3.3 9.0 6.5 1.2 16.4 8.5 13.9 9.6 7.4 13.9 12.3 16.8 3.2 23.9 22.6 9.7 10.5 2.8 2.3 3.9 2.5 10.3 8.0 1.5 11.5 22.8 8.2 16.6 19.4 7.4 8.4 5.4 6.3 23.6 4.6 9.4 10.2 10.8 7.1 14.4 3.6 12.6 3.9 0.5 12.9 5.4 2.3 2.5 5.9 8.5 8.7 2.5 4.8 29.0 2.3 11.2 0.6 14.6 22.2 6.8 13.9 3.8 9.3 5.9 10.7 9.8 1.6 13.9 21.7 7.2 2.9 5.4 1.3 8.9 8.7 10.2 12.5 9.7 9.4 10.6 12.0 9.8 9.2 0.4 9.4 20.1 9.4 8.4 7.3 2.3 2.8 3.0 3.6 2.4 2.9 2.5 2.5 2.8 2.8 2.5 3.3 12.3 9.6 11.9 12.1 18.5 12.6 13.3 20.1 13.6 6.1 14.8 10.7 3.7 15.7 9.6 11.0 0.0 26.4 11.4 2.9 11.7 13.7 0.7 12.9 12.0 10.2 1.8 20.4 14.7 16.0 27.9 13.1 9.7 13.7 5.1 12.9 16.1 17.6 16.3 3.3 15.6 10.8 12.2 6.5 12.3 1.5 10.5 10.0 19.6 5.6 5.8 8.7 8.2 25.1 26.7 9.8 6.8 10.5 17.4 5.1 9.7 24.8 14.7 8.7 6.6 11.4 18.9 24.9 23.8 15.8 14.2 12.4 12.7 16.5 10.5 9.4 FCF1 "Bka, C14orf111, CGI-35, UTP24" ENSG00000119616 "FCF1 rRNA-processing protein" Q9Y324 14 74713144-74738620 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 104.7;Smooth muscle cells: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA046681 Approved Approved Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA046681: AB_10960541" "unprognostic (1.39e-2)" "unprognostic (1.54e-1)" "unprognostic (5.74e-2)" "unprognostic (1.01e-2)" "unprognostic (1.18e-1)" "unprognostic (7.94e-3)" "prognostic unfavorable (5.54e-6)" "unprognostic (3.17e-1)" "unprognostic (3.43e-2)" "unprognostic (7.36e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (7.79e-2)" "prognostic favorable (2.26e-4)" "unprognostic (3.30e-1)" "unprognostic (1.46e-1)" "unprognostic (3.03e-1)" "unprognostic (1.47e-1)" 32.5 23.1 9.9 25.4 12.7 27.0 34.9 12.7 13.0 30.5 11.5 28.6 18.9 29.2 20.9 24.9 38.4 22.0 26.8 9.4 12.1 30.1 32.8 27.9 34.4 12.5 12.7 39.9 16.5 26.6 12.9 32.1 12.8 28.2 29.3 13.2 19.9 30.6 25.3 17.3 20.5 30.2 11.3 23.5 23.0 18.4 11.4 33.2 43.3 22.4 41.3 29.2 19.0 17.4 109.3 78.7 55.8 63.5 86.8 76.3 73.5 93.6 71.7 91.4 81.2 88.1 87.3 97.2 59.6 82.1 44.2 78.5 94.1 88.5 160.7 90.6 40.8 67.4 46.4 57.9 62.6 83.1 59.5 60.3 76.6 97.3 101.4 72.4 86.6 82.7 82.2 56.9 83.3 77.5 97.0 29.6 75.0 63.2 90.5 72.9 109.5 46.3 46.4 88.1 39.1 56.9 120.1 62.8 55.0 61.4 80.7 57.0 79.9 72.7 77.6 69.5 108.3 49.9 140.7 147.7 69.2 77.5 82.5 13.5 17.0 20.5 19.1 15.3 21.0 24.3 18.4 16.6 13.9 21.2 19.5 20.5 14.7 15.3 18.8 31.3 19.6 9.2 9.9 12.7 12.7 13.0 9.4 12.1 12.5 12.7 12.8 11.3 11.4 17.4 11.9 6.4 18.3 7.5 18.8 3.1 7.6 10.5 11.4 7.5 12.2 7.5 24.0 34.3 14.9 12.9 6.2 11.8 26.6 16.3 15.6 17.4 23.8 28.0 18.5 13.7 10.2 36.2 11.6 19.0 14.7 13.3 6.1 13.5 26.0 9.3 28.5 104.7 12.8 11.8 11.7 15.9 8.2 33.6 4.3 11.9 15.5 12.6 0.0 7.5 16.4 13.5 24.7 11.6 17.5 17.4 10.3 17.0 12.0 6.1 13.1 18.4 45.4 7.2 13.1 12.5 67.7 12.4 12.3 11.1 4.8 8.8 14.3 8.2 15.6 6.7 FCHO2 ENSG00000157107 "FCH and mu domain containing endocytic adaptor 2" Q0JRZ9 5 72956041-73090522 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 19.3;neutrophil: 20.6" "Group enriched" "Detected in many" 9 "granulocytes: 20.6;monocytes: 6.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037685, HPA037686, HPA077850" Enhanced Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Centrosome "Vesicles, Cytosol" "HPA037685: AB_2675610, HPA037686: AB_10673636, HPA077850: AB_2686860" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" "unprognostic (1.01e-2)" "unprognostic (1.10e-1)" "unprognostic (6.59e-2)" "unprognostic (2.68e-3)" "unprognostic (4.99e-2)" "unprognostic (6.25e-2)" "unprognostic (1.31e-1)" "unprognostic (5.67e-2)" "unprognostic (6.56e-3)" "unprognostic (1.21e-1)" "prognostic favorable (7.00e-5)" "unprognostic (1.43e-1)" "unprognostic (3.27e-3)" "unprognostic (9.59e-2)" "unprognostic (1.76e-1)" 16.6 9.8 5.1 11.3 6.5 10.7 15.0 9.8 9.1 14.5 11.4 16.3 17.1 16.1 9.0 29.6 11.3 16.9 10.6 5.2 5.0 19.7 17.9 21.8 11.0 6.7 5.6 14.9 9.1 15.3 4.1 21.2 6.4 13.0 17.1 9.1 11.6 12.6 10.4 12.3 18.6 13.4 5.3 17.1 13.6 7.2 8.8 5.2 24.0 12.2 9.2 14.9 16.5 9.5 15.0 11.8 11.3 9.9 15.6 20.5 33.0 12.9 19.0 9.6 15.1 6.0 25.6 3.5 17.6 18.0 17.8 11.1 9.6 22.6 13.0 3.8 11.3 7.3 9.9 7.6 7.8 1.5 7.3 13.8 11.5 12.8 20.6 21.9 22.3 3.5 8.4 6.2 20.2 7.0 0.0 7.3 3.6 3.0 6.1 3.2 10.8 4.4 23.4 20.8 4.5 7.1 17.7 12.6 8.3 15.7 15.1 10.4 23.1 12.5 5.8 13.9 9.3 2.2 4.4 0.7 8.1 1.1 15.8 19.3 3.2 8.8 1.5 4.6 1.0 0.4 0.5 0.6 1.4 0.9 0.2 0.5 20.6 0.9 6.6 0.5 0.4 0.8 5.1 6.5 9.8 9.1 5.2 5.0 6.7 5.6 6.4 5.3 8.8 9.5 51.8 57.7 44.3 34.9 3.8 10.5 15.6 12.0 12.5 11.1 16.5 12.3 15.1 14.3 23.1 35.0 4.2 14.2 7.0 25.6 13.7 16.0 2.4 24.3 17.0 36.8 14.9 12.6 78.2 17.5 8.9 22.8 17.3 38.3 18.3 9.5 52.1 11.0 19.8 11.8 51.5 14.8 8.2 81.0 13.0 2.8 13.4 45.8 16.0 71.2 12.9 15.4 3.1 62.4 59.1 30.7 29.4 13.9 3.5 22.5 21.0 21.8 21.5 8.9 26.3 25.1 21.3 16.9 14.3 15.0 15.3 13.7 4.4 9.1 14.0 30.2 FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 83.4;lymphoid tissue: 110.9" "Cell type enhanced" "Detected in many" "Adipocytes: 46.8;Hofbauer cells: 48.7;Kupffer cells: 92.3;Macrophages: 51.9;monocytes: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 315.8" "Group enriched" "Detected in many" 4 "dendritic cells: 162.6;granulocytes: 315.8;monocytes: 151.7" "Cell line enhanced" "Detected in many" "HEL: 63.5;HL-60: 56.9;HMC-1: 116.6;NB-4: 76.1;THP-1: 110.8;U-937: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" 30.8 8.0 9.4 20.2 8.8 83.4 21.3 9.6 10.8 18.1 9.6 12.5 5.8 15.7 2.4 5.9 19.0 14.0 19.6 8.3 8.7 18.9 25.2 30.9 13.8 11.1 9.2 13.5 7.8 2.3 5.6 16.3 10.1 17.9 4.6 1.5 58.3 8.0 6.1 8.0 12.5 10.7 10.4 110.9 9.6 4.5 10.9 4.2 16.0 7.0 5.7 15.1 13.5 9.8 0.4 0.8 0.8 10.3 3.1 8.8 17.9 2.9 0.1 5.1 2.9 2.6 0.1 6.8 0.5 6.0 0.2 1.5 1.7 0.3 1.6 3.3 1.1 63.5 0.0 11.9 6.8 56.9 116.6 8.8 0.1 7.6 0.0 0.0 31.2 9.4 1.8 0.2 0.0 21.3 1.8 76.1 3.2 2.5 0.0 8.6 0.1 0.1 0.0 0.2 0.4 0.1 0.0 2.8 2.3 2.9 0.1 110.8 24.9 0.2 10.4 0.2 0.2 0.1 8.0 2.5 0.3 48.0 2.4 64.4 151.7 315.8 0.5 88.6 0.4 5.2 0.3 0.4 162.6 4.1 0.2 0.3 100.5 51.4 39.8 65.0 0.2 81.5 9.4 8.8 9.6 10.8 8.3 8.7 11.1 9.2 10.1 10.4 10.9 9.8 46.8 3.2 5.8 3.6 5.0 3.8 5.4 0.5 0.6 0.2 4.1 3.8 3.4 8.6 0.5 1.8 0.0 5.3 25.6 0.6 3.9 7.3 1.7 2.0 4.2 29.1 3.0 8.0 2.8 4.3 4.2 9.0 2.0 4.2 29.2 10.7 20.0 15.0 48.7 0.0 0.2 2.0 2.0 92.3 27.9 8.4 9.0 51.9 7.2 5.6 57.8 2.5 26.8 2.0 0.3 2.1 2.0 10.1 4.0 3.1 0.7 1.5 0.2 1.9 13.1 4.6 12.9 4.4 15.9 1.0 2.8 4.5 6.7 3.3 3.7 5.2 FIP1L1 "DKFZp586K0717, FIP1" ENSG00000145216 "Factor interacting with PAPOLA and CPSF1" Q6UN15 4 53377641-53460862 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "mRNA processing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA037475, HPA058202" Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA037475: AB_10696933, HPA058202: AB_2683636" "unprognostic (3.80e-1)" "unprognostic (5.46e-2)" "unprognostic (5.60e-3)" "unprognostic (1.40e-1)" "unprognostic (7.18e-2)" "unprognostic (4.71e-2)" "prognostic unfavorable (1.51e-4)" "unprognostic (1.87e-1)" "unprognostic (9.00e-3)" "unprognostic (1.14e-2)" "unprognostic (5.48e-2)" "unprognostic (1.42e-1)" "unprognostic (4.07e-1)" "unprognostic (1.10e-1)" "unprognostic (8.66e-3)" "unprognostic (3.10e-2)" "unprognostic (1.39e-1)" 19.1 15.7 5.8 14.8 5.9 31.8 17.0 11.3 8.7 18.4 1.2 14.3 11.7 17.9 12.7 15.9 16.0 11.0 13.0 4.9 9.9 13.3 13.7 14.2 20.2 4.8 5.1 22.0 9.7 16.4 9.7 21.1 4.9 12.3 15.1 17.0 14.7 11.4 25.8 17.9 14.4 15.9 4.6 14.8 14.4 31.4 7.0 29.4 14.6 11.7 23.3 17.5 16.2 8.7 43.7 29.5 51.8 32.6 36.4 31.9 63.5 52.8 64.0 45.1 35.0 43.2 37.8 79.5 42.6 47.2 44.4 26.7 55.6 37.9 55.8 27.0 31.0 60.0 25.5 40.7 51.2 95.4 53.6 31.2 35.6 51.6 49.8 42.0 32.3 47.7 71.3 34.3 34.1 33.3 88.5 44.4 35.9 53.7 28.8 79.2 22.0 36.9 33.9 34.7 40.8 41.5 37.6 40.3 65.1 47.0 25.2 33.6 33.9 44.2 39.7 39.9 67.2 43.3 27.8 100.8 38.4 59.2 84.3 45.2 23.3 51.4 32.5 25.0 38.8 34.8 33.0 32.9 31.9 32.3 36.6 32.3 28.3 50.7 37.0 46.5 45.9 33.1 5.8 5.9 11.3 8.7 4.9 9.9 4.8 5.1 4.9 4.6 7.0 8.7 36.1 25.6 25.4 47.0 50.4 38.7 46.6 41.5 30.1 41.2 24.0 25.4 14.4 21.5 34.1 27.6 18.8 58.7 54.0 26.9 37.2 45.8 10.3 37.6 51.1 33.4 36.6 29.2 78.8 34.9 52.2 41.9 29.6 41.6 49.4 40.0 28.5 21.2 33.2 77.4 78.7 27.0 32.6 19.8 24.6 15.2 66.8 32.2 32.0 60.9 41.3 48.6 29.9 137.7 91.4 36.9 33.3 53.4 40.3 36.5 25.2 23.3 44.8 30.3 39.5 38.9 46.9 118.5 87.6 31.8 34.1 86.3 49.8 56.8 29.4 38.5 FKBP3 "FKBP-25, FKBP25" ENSG00000100442 "FKBP prolyl isomerase 3" Q00688 14 45115599-45135319 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 424.4;tongue: 372.0" "Cell type enhanced" "Detected in all" "Late spermatids: 377.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000864, CAB012232, CAB012520" Supported Supported Cytosol NA NA 1300000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB012232: , CAB012520: AB_873554, HPA000864: AB_1078873" "unprognostic (7.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.18e-1)" "unprognostic (9.72e-2)" "unprognostic (1.25e-1)" "unprognostic (9.82e-3)" "unprognostic (3.58e-3)" "unprognostic (2.28e-1)" "unprognostic (5.04e-3)" "unprognostic (1.22e-3)" "unprognostic (7.47e-2)" "unprognostic (6.92e-3)" "unprognostic (1.00e-1)" "unprognostic (3.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-2)" "unprognostic (1.47e-1)" 40.9 46.8 100.3 35.8 102.3 38.4 50.0 110.1 122.1 38.1 91.8 49.4 44.7 31.4 64.8 54.7 31.4 29.8 109.5 101.9 100.6 66.5 69.7 27.6 53.7 100.7 99.3 35.3 32.8 55.5 56.6 46.9 100.1 57.7 49.1 82.3 37.1 37.9 424.4 38.3 47.8 39.2 99.8 39.9 38.0 52.9 101.4 59.6 40.1 372.0 57.7 43.3 38.6 105.8 161.0 175.3 249.0 132.4 109.0 117.8 98.3 96.2 110.3 149.3 163.5 154.8 134.1 85.1 98.9 110.0 84.1 130.0 188.4 124.8 211.7 123.7 111.0 69.8 138.8 202.6 107.1 122.2 72.8 112.0 127.5 87.2 80.1 136.8 198.0 131.9 102.9 62.1 179.9 196.9 197.5 163.0 126.7 178.3 164.5 187.0 183.7 102.9 242.2 183.7 151.2 59.2 154.8 94.5 156.0 186.4 222.6 89.9 128.7 113.0 195.6 59.9 75.1 104.0 198.8 132.5 68.3 83.0 108.1 23.4 22.4 22.1 18.7 27.3 22.8 29.7 25.0 25.7 33.3 21.8 23.4 26.7 3.6 24.2 29.4 43.0 30.8 20.2 100.3 102.3 110.1 122.1 101.9 100.6 100.7 99.3 100.1 99.8 101.4 105.8 48.3 41.7 46.6 25.8 45.3 47.8 94.4 205.5 45.5 79.3 39.9 46.7 202.5 48.6 101.4 93.8 10.4 320.9 51.2 56.4 252.4 131.1 212.7 55.0 83.3 58.5 56.1 50.9 49.7 73.0 135.4 70.0 36.7 68.1 53.7 75.6 38.2 91.1 131.1 40.4 44.5 71.2 124.1 39.9 43.0 377.4 80.8 53.7 69.4 17.8 110.7 80.7 50.4 21.1 34.3 88.4 53.7 97.8 58.0 76.4 91.8 220.1 73.5 67.4 105.2 71.3 118.5 154.0 111.2 65.0 47.9 165.0 48.8 84.1 96.1 77.6 FKBPL "DIR1, NG7, WISp39" ENSG00000204315 "FKBP prolyl isomerase like" Q9UIM3 6 32128707-32130288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 51.2;Squamous epithelial cells: 34.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043478, HPA060158" Approved Approved "Nucleoplasm,Mitotic spindle" Yes No "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Mitotic spindle" "HPA043478: AB_2678500, HPA060158: AB_2684213" "unprognostic (1.80e-1)" "unprognostic (6.80e-2)" "unprognostic (1.14e-1)" "unprognostic (1.03e-3)" "unprognostic (1.02e-1)" "unprognostic (7.67e-2)" "unprognostic (8.22e-3)" "unprognostic (2.25e-2)" "unprognostic (1.22e-1)" "prognostic favorable (8.46e-4)" "unprognostic (1.30e-1)" "unprognostic (8.96e-2)" "unprognostic (5.79e-2)" "unprognostic (7.32e-2)" "unprognostic (4.39e-2)" "unprognostic (2.70e-1)" "unprognostic (1.13e-1)" 3.3 4.2 2.9 2.0 2.5 2.8 4.0 2.2 3.2 3.8 2.2 4.1 1.6 3.1 6.1 10.7 4.3 1.6 2.9 2.6 2.4 4.0 5.2 3.2 3.1 2.9 2.4 3.2 5.5 4.0 2.9 1.7 2.6 3.2 3.4 1.8 6.4 1.1 4.5 9.8 3.6 3.6 2.1 4.7 6.1 6.2 2.5 5.5 5.6 4.4 1.1 2.9 5.1 3.6 0.0 0.9 8.1 13.8 11.6 8.2 3.4 5.4 6.1 10.0 9.7 17.5 7.3 0.0 1.8 9.3 13.1 4.2 11.3 10.5 6.9 0.0 13.7 0.0 11.9 10.2 6.5 0.0 6.6 8.0 5.6 19.3 6.1 7.3 10.6 15.8 11.9 15.0 10.2 6.0 6.9 5.9 6.0 16.1 3.0 0.0 5.0 13.6 10.4 1.5 15.3 1.0 5.5 9.6 10.2 2.4 16.8 11.8 4.7 14.3 4.1 7.5 13.3 7.7 1.5 5.7 5.6 7.1 9.1 6.6 1.8 0.5 0.7 2.5 0.7 2.1 1.1 1.3 1.9 0.5 1.0 1.0 2.6 3.4 0.8 1.6 0.3 1.5 2.9 2.5 2.2 3.2 2.6 2.4 2.9 2.4 2.6 2.1 2.5 3.6 8.8 6.4 5.9 0.3 7.8 11.2 4.7 6.7 51.2 2.9 11.5 8.5 2.0 7.2 6.2 1.8 0.0 9.9 6.1 9.3 5.9 8.1 4.2 11.6 6.1 9.6 6.0 19.8 0.7 6.7 13.3 5.6 6.1 8.1 2.5 12.4 5.0 3.3 5.0 10.1 0.6 7.0 8.2 2.8 8.8 5.5 2.8 4.2 7.2 1.0 3.7 7.3 3.1 0.0 0.5 6.0 6.2 3.4 7.7 5.2 10.3 9.9 3.2 4.9 0.0 5.4 17.4 11.1 8.8 34.1 10.2 14.1 6.8 14.9 6.5 4.1 FOXG1 "BF1, FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B, FOXG1C, HBF-3, HFK1, HFK2, HFK3, QIN" ENSG00000176165 "Forkhead box G1" P55316 14 28766787-28770277 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 25.3" "Cell type enhanced" "Detected in some" "Astrocytes: 69.5;Excitatory neurons: 35.9;Inhibitory neurons: 33.2;Oligodendrocyte precursor cells: 31.2;Spermatocytes: 15.4" "Cancer enriched" "Detected in some" 10 "glioma: 15.9" "Group enriched" "Detected in many" 37 "amygdala: 11.6;basal ganglia: 20.1;cerebral cortex: 25.3;hippocampal formation: 21.5;white matter: 8.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 15.6;SCLC-21H: 39.0;U-138 MG: 25.2;U-251 MG: 25.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 10: Non-specific - Unknown function" "unprognostic (2.92e-2)" "unprognostic (2.22e-1)" "unprognostic (1.92e-1)" "unprognostic (3.49e-1)" "unprognostic (1.17e-3)" "unprognostic (2.14e-2)" "unprognostic (1.27e-11)" "unprognostic (4.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.60e-2)" 0.0 0.0 11.6 0.0 20.1 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 21.5 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.2 3.1 0.2 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 7.6 6.0 4.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 3.4 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.0 0.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.1 0.0 2.3 0.0 0.1 0.1 25.2 0.0 2.0 25.2 0.0 0.0 0.0 8.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 20.1 0.0 25.3 21.5 0.4 0.0 0.0 0.0 0.0 0.2 8.9 0.0 0.0 0.0 69.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 35.9 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 33.2 0.0 0.0 0.0 0.0 3.4 0.3 0.0 0.0 4.7 0.0 1.4 0.0 31.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 9.5 15.4 2.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 FRG1 "FRG1A, FSG1" ENSG00000109536 "FSHD region gene 1" Q14331 4 189940870-189963202 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Myogenesis, Ribosome biogenesis, rRNA processing" "Actin-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA075683 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" "HPA075683: " "unprognostic (1.67e-1)" "unprognostic (1.04e-2)" "unprognostic (1.24e-1)" "unprognostic (1.52e-1)" "unprognostic (5.56e-2)" "unprognostic (7.14e-2)" "unprognostic (5.62e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-3)" "unprognostic (2.83e-3)" "unprognostic (2.55e-1)" "unprognostic (2.42e-1)" "unprognostic (3.84e-3)" "prognostic favorable (9.65e-4)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (1.01e-1)" 36.8 25.7 6.0 6.4 6.0 16.6 33.9 6.1 13.0 29.5 6.1 35.0 6.6 32.9 9.6 30.7 27.6 5.9 31.9 6.0 6.1 29.2 24.8 23.5 7.9 6.0 6.0 32.0 30.6 13.1 18.5 5.9 6.0 21.7 7.7 3.6 24.9 7.5 31.1 28.6 26.7 8.6 6.0 29.0 30.0 19.8 6.0 13.0 23.4 9.4 8.4 28.8 28.3 6.1 12.2 8.5 21.5 19.0 11.0 16.4 14.6 18.0 13.4 23.3 15.6 6.1 20.1 21.9 8.5 13.5 8.8 7.3 20.3 13.8 24.6 13.3 9.6 39.4 9.3 4.3 18.8 28.9 14.9 12.1 15.5 12.9 4.2 15.8 15.5 19.1 25.4 42.4 19.0 6.9 38.6 42.7 4.4 5.4 12.8 27.2 4.9 14.4 16.3 6.9 15.8 15.7 11.4 13.0 21.1 11.8 6.7 20.3 15.4 8.8 11.6 6.5 13.4 15.4 12.8 17.6 15.7 18.7 13.1 30.7 13.4 19.7 13.6 18.0 13.8 16.9 16.0 15.1 12.1 15.4 13.6 14.8 13.3 16.9 19.1 13.4 20.1 13.6 6.0 6.0 6.1 13.0 6.0 6.1 6.0 6.0 6.0 6.0 6.0 6.1 69.3 80.1 52.9 6.5 61.9 33.4 42.5 62.9 18.2 43.1 47.6 56.9 70.6 64.3 52.9 33.1 16.7 77.0 82.2 45.6 131.0 106.0 50.4 42.4 51.4 61.1 44.9 94.1 12.5 121.9 65.2 50.9 18.8 40.9 84.2 34.8 83.6 133.8 68.1 32.0 11.6 53.9 50.8 92.6 46.7 20.4 76.1 57.4 21.4 4.7 107.6 61.1 124.6 12.5 17.0 88.4 48.9 72.6 41.9 20.7 60.8 126.2 51.7 52.0 52.6 50.7 84.6 75.9 70.6 27.5 28.1 53.5 64.6 42.8 52.9 32.4 FTSJ3 SPB1 ENSG00000108592 "FtsJ RNA 2'-O-methyltransferase 3" Q8IY81 17 63819433-63830012 "Metabolic proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055544, HPA062628" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA055544: AB_2682843, HPA062628: AB_2684813" "unprognostic (1.33e-1)" "unprognostic (1.41e-1)" "unprognostic (6.60e-2)" "unprognostic (7.82e-2)" "unprognostic (6.45e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (1.27e-1)" "unprognostic (2.57e-1)" "unprognostic (2.41e-2)" "unprognostic (2.85e-1)" "unprognostic (1.12e-1)" "unprognostic (4.99e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (5.10e-1)" "unprognostic (3.43e-1)" 20.7 20.7 11.8 18.2 12.4 15.8 18.0 12.3 12.7 20.4 12.0 20.5 14.2 20.2 17.2 19.0 18.8 15.1 20.8 11.3 12.0 23.3 18.8 14.8 20.9 12.6 12.1 22.3 15.7 20.6 12.4 13.1 12.5 18.7 18.0 8.8 17.7 18.1 28.8 23.9 18.4 22.6 12.3 21.0 17.8 15.2 12.3 21.0 17.2 14.6 23.8 20.1 18.7 12.7 63.0 97.0 36.8 52.5 57.9 49.5 57.0 61.4 44.7 68.8 54.2 81.4 40.9 83.4 24.7 36.2 36.0 42.6 69.3 58.4 87.8 14.4 69.2 75.0 68.6 76.6 42.2 95.9 52.5 35.1 45.3 106.9 51.2 34.9 58.2 50.2 75.9 33.1 46.5 105.5 84.9 31.1 99.4 70.2 97.7 74.6 100.9 58.6 44.8 56.3 33.9 132.5 72.3 60.9 43.1 72.7 58.0 31.8 52.7 50.9 71.6 57.4 115.1 79.5 120.9 81.4 45.6 62.6 50.3 4.5 11.4 7.0 11.0 13.0 14.5 9.6 11.6 14.5 13.6 8.6 9.2 11.5 2.5 13.9 10.1 10.3 15.1 10.0 11.8 12.4 12.3 12.7 11.3 12.0 12.6 12.1 12.5 12.3 12.3 12.7 16.2 32.1 30.2 4.2 17.3 13.8 13.6 16.1 26.7 6.6 10.6 12.6 27.7 18.6 25.7 14.7 10.4 16.0 19.4 15.7 13.7 28.0 8.8 23.5 27.5 25.1 12.7 20.8 2.0 33.8 17.0 18.4 11.2 24.1 24.1 17.5 14.3 19.9 14.2 3.3 2.0 12.0 16.2 13.8 9.3 17.8 24.2 16.3 8.8 1.9 19.3 16.0 15.5 1.5 3.8 30.6 14.0 19.2 18.6 10.6 15.5 29.8 24.3 9.3 46.0 21.0 20.5 11.7 15.7 20.8 12.8 16.3 18.6 15.7 21.1 9.5 FUBP1 "FBP, FUBP" ENSG00000162613 "Far upstream element binding protein 1" Q96AE4 1 77944055-77979110 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006149 Supported Enhanced Nucleoplasm NA NA 300000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA006149: AB_1849172" "unprognostic (4.17e-2)" "unprognostic (2.83e-2)" "unprognostic (3.35e-3)" "unprognostic (3.89e-2)" "unprognostic (3.77e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (9.83e-9)" "unprognostic (2.32e-2)" "unprognostic (2.16e-1)" "unprognostic (1.69e-1)" "unprognostic (3.31e-3)" "unprognostic (9.80e-3)" "unprognostic (9.02e-3)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (6.24e-2)" "unprognostic (9.46e-2)" 29.6 37.8 13.4 35.5 15.3 79.6 30.9 24.0 17.9 28.1 18.5 24.3 24.9 36.4 36.8 24.8 28.5 16.8 29.7 13.8 15.9 39.3 17.1 31.6 42.8 15.6 13.4 46.9 33.7 23.0 41.7 23.0 15.7 24.1 27.5 57.2 30.5 13.3 33.8 27.5 27.5 19.0 15.1 35.2 26.1 17.0 15.3 35.7 36.9 15.2 38.6 25.3 27.4 24.3 49.4 36.5 106.9 40.0 11.9 19.0 77.6 53.5 23.4 35.8 29.2 34.7 49.1 91.3 22.1 31.9 49.1 51.4 54.8 45.4 48.1 91.6 38.5 58.8 87.4 56.9 25.8 104.9 22.8 25.2 35.5 39.7 36.4 39.6 29.2 59.1 65.8 45.1 31.0 39.0 74.0 60.4 75.7 38.0 26.2 94.6 78.7 30.9 35.2 49.0 54.2 61.1 41.5 42.8 44.2 44.7 52.9 38.7 50.7 50.7 66.0 14.7 62.5 44.8 39.4 106.1 21.1 45.3 44.5 6.5 10.5 12.3 20.5 17.0 23.3 19.0 19.6 20.8 9.3 14.7 19.4 23.6 5.3 29.4 19.1 15.4 24.5 15.3 13.4 15.3 24.0 17.9 13.8 15.9 15.6 13.4 15.7 15.1 15.3 24.3 38.6 73.7 57.5 48.0 70.7 84.8 107.0 49.5 39.3 44.7 48.7 31.2 76.4 24.3 71.0 33.1 41.7 46.8 68.2 27.1 43.0 59.5 33.3 54.8 50.7 52.0 55.1 43.1 48.8 72.1 66.2 49.0 28.5 60.5 77.8 59.4 30.4 23.4 33.4 18.5 53.6 35.9 36.7 32.1 37.0 19.8 48.1 41.8 39.2 61.8 61.5 32.5 52.5 56.3 88.3 69.2 33.5 30.1 68.9 54.2 23.6 28.9 73.2 40.5 32.9 70.3 65.7 33.2 41.3 40.9 63.1 35.7 72.1 38.0 37.8 72.7 GAPVD1 "DKFZP434C212, KIAA1521" ENSG00000165219 "GTPase activating protein and VPS9 domains 1" Q14C86 9 125261794-125367207 "Predicted intracellular proteins" Endocytosis "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029386, HPA029387, HPA074882" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA 46000 "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" Cytosol "HPA029386: AB_10599604, HPA029387: AB_10600311, HPA074882: " "unprognostic (8.43e-3)" "unprognostic (3.84e-2)" "unprognostic (3.53e-1)" "unprognostic (1.97e-1)" "unprognostic (5.43e-2)" "unprognostic (4.04e-2)" "unprognostic (7.08e-2)" "unprognostic (1.31e-2)" "unprognostic (7.56e-2)" "unprognostic (1.23e-1)" "unprognostic (2.77e-1)" "unprognostic (1.27e-1)" "unprognostic (2.54e-3)" "unprognostic (2.77e-1)" "unprognostic (4.19e-2)" "unprognostic (1.67e-2)" "unprognostic (5.82e-2)" 12.3 9.8 8.1 12.2 11.1 23.0 12.0 11.7 9.4 12.2 13.1 10.3 8.0 11.1 9.8 17.0 10.7 10.3 9.7 8.4 8.8 13.0 11.2 15.7 12.6 9.8 8.9 12.1 10.6 18.7 8.2 18.4 10.0 10.5 9.8 16.5 9.3 12.4 19.1 14.7 9.2 13.3 10.1 12.7 9.6 26.8 9.7 14.1 18.9 18.7 15.0 12.2 10.1 14.2 22.8 23.2 21.8 20.0 26.2 28.6 30.5 25.0 28.9 29.0 24.2 37.0 15.9 30.2 13.3 31.9 28.7 44.9 46.2 25.8 31.1 28.1 27.1 34.6 53.1 18.4 30.1 41.4 56.0 20.1 25.2 34.6 27.2 18.7 35.0 23.8 68.8 16.3 24.3 33.2 31.2 18.0 21.6 41.2 26.2 27.2 47.6 29.1 16.2 23.2 28.8 18.9 36.9 32.6 20.0 21.7 40.9 20.9 36.1 19.9 14.3 35.7 27.2 20.7 42.3 29.9 24.1 22.9 26.4 25.6 15.9 19.6 13.0 15.4 12.7 10.0 13.5 14.6 15.4 9.5 13.3 14.3 19.5 15.2 19.8 5.8 11.8 11.3 8.1 11.1 11.7 9.4 8.4 8.8 9.8 8.9 10.0 10.1 9.7 14.2 30.0 109.0 58.0 35.6 28.3 31.9 18.2 23.0 32.5 29.9 21.0 17.5 66.8 14.3 34.8 27.6 52.1 42.3 20.7 16.6 9.8 16.2 58.3 35.7 30.7 26.8 12.6 77.0 68.4 19.3 23.7 26.2 18.3 31.4 15.8 27.6 21.4 15.2 27.6 35.3 69.7 15.9 10.2 25.4 28.5 17.7 23.0 30.5 17.8 51.5 31.2 22.8 18.6 45.2 62.7 22.3 13.9 24.0 26.5 20.0 15.4 16.1 57.2 39.1 19.7 27.8 32.0 85.6 34.5 32.3 36.9 67.0 28.3 32.5 17.0 29.8 GBA "GBA1, GLUC" ENSG00000177628 "Glucosylceramidase beta" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 65.2;Syncytiotrophoblasts: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" NA NA 470000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "CAB037171: AB_1078958, CAB037289: AB_1078957, HPA006667: AB_1078979" "unprognostic (6.03e-2)" "unprognostic (6.02e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-1)" "unprognostic (6.00e-3)" "unprognostic (2.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.76e-2)" "unprognostic (1.22e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-1)" "unprognostic (2.94e-2)" 23.9 37.9 22.5 24.8 24.4 41.7 25.1 25.9 24.3 26.7 27.4 35.1 23.9 22.9 50.2 27.6 20.5 28.3 19.1 26.1 27.7 33.6 33.7 28.3 19.9 27.3 28.0 16.9 33.4 103.1 43.8 39.2 36.2 23.3 39.8 12.4 26.8 33.6 9.1 33.4 22.5 29.7 25.0 29.0 22.7 8.8 29.2 19.7 37.7 13.6 28.0 27.1 21.9 29.5 38.0 72.2 25.1 34.2 254.8 55.8 29.3 65.4 230.4 95.3 119.0 43.2 135.7 26.3 70.4 153.7 152.0 76.2 35.9 46.4 50.3 55.5 25.1 21.8 45.1 23.2 73.6 25.8 87.0 73.4 38.2 199.7 30.2 100.2 85.6 22.2 23.4 42.9 113.5 82.6 32.5 11.9 16.3 61.9 51.2 26.8 41.9 108.1 63.9 29.0 23.9 33.5 57.4 136.4 145.3 45.6 102.6 63.3 65.7 71.7 31.7 91.9 53.7 86.2 78.6 20.4 126.6 23.4 56.4 21.4 36.0 15.3 20.8 35.8 13.2 11.1 15.7 13.8 22.4 7.8 11.0 11.7 28.9 11.6 37.2 12.5 23.4 23.3 22.5 24.4 25.9 24.3 26.1 27.7 27.3 28.0 36.2 25.0 29.2 29.5 6.8 3.2 5.1 3.3 8.8 6.0 5.8 9.5 4.6 4.0 12.7 6.5 8.8 17.2 8.1 12.9 2.1 30.7 6.2 36.1 3.9 30.5 1.4 12.3 9.7 12.2 14.6 7.4 3.4 32.4 27.9 18.6 20.9 17.9 7.0 7.9 17.2 23.2 65.2 5.0 2.7 11.6 4.1 33.3 9.9 2.8 9.9 26.8 26.6 1.0 22.8 11.7 12.3 0.5 3.3 29.5 15.8 9.1 19.8 6.7 28.6 20.6 8.5 6.0 0.0 9.4 21.6 22.5 12.5 8.6 4.4 59.4 8.5 6.0 10.4 6.5 GDPD1 "FLJ37451, GDE4" ENSG00000153982 "Glycerophosphodiester phosphodiesterase domain containing 1" Q8N9F7 17 59220467-59275970 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 34.3;Early spermatids: 47.2;Excitatory neurons: 65.1;Inhibitory neurons: 63.9;Oligodendrocyte precursor cells: 34.2;Oligodendrocytes: 36.5;Spermatocytes: 52.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 22.3;K-562: 12.5;SCLC-21H: 12.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "unprognostic (8.33e-2)" "unprognostic (6.63e-3)" "unprognostic (2.68e-2)" "unprognostic (5.98e-3)" "unprognostic (7.12e-2)" "unprognostic (5.35e-2)" "unprognostic (4.85e-6)" "prognostic favorable (2.98e-4)" "unprognostic (2.00e-1)" "unprognostic (1.36e-2)" "unprognostic (1.24e-3)" "unprognostic (2.73e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-3)" "unprognostic (4.72e-2)" "unprognostic (1.32e-2)" "unprognostic (6.28e-3)" 0.8 1.8 4.7 0.9 4.3 1.5 1.8 7.0 8.4 1.1 1.9 1.8 5.7 1.5 0.7 0.8 1.4 1.8 1.1 5.1 4.7 2.0 1.0 2.3 0.9 5.9 5.4 0.9 1.1 5.9 1.8 1.3 6.3 2.0 1.5 5.8 2.3 1.5 1.7 1.4 4.2 1.3 2.8 1.5 5.2 8.6 5.1 1.6 2.6 0.7 1.1 1.3 0.8 5.4 0.8 1.0 4.2 3.2 0.6 0.2 2.6 0.5 1.6 0.4 3.3 0.0 1.3 2.0 4.7 0.1 3.0 0.6 6.6 1.1 1.9 2.6 6.8 22.3 0.7 3.2 2.0 1.0 3.2 0.6 5.4 2.1 0.6 1.9 1.9 4.9 12.5 1.3 0.8 1.0 3.9 0.4 0.8 6.6 1.1 2.4 0.4 2.1 2.0 1.2 12.5 3.4 1.0 0.4 4.6 1.3 3.0 1.4 1.6 0.2 1.3 0.2 0.4 3.7 2.3 0.7 1.0 1.2 1.4 2.4 0.5 0.3 0.5 0.7 0.4 0.3 0.4 0.6 0.2 0.5 0.5 0.7 0.9 0.8 0.7 0.7 0.3 0.3 4.7 4.3 7.0 8.4 5.1 4.7 5.9 5.4 6.3 2.8 5.1 5.4 1.6 3.2 8.2 34.3 1.3 0.5 1.5 1.2 1.8 6.1 1.6 1.0 3.1 0.0 8.7 5.5 10.4 0.4 3.2 0.9 0.0 2.2 47.2 1.8 0.4 1.4 1.2 11.3 65.1 1.8 5.5 1.1 9.2 0.7 0.0 4.0 0.7 0.6 1.9 6.7 63.9 3.1 6.1 2.6 1.0 8.3 0.6 3.0 1.8 2.8 2.7 2.3 3.1 34.2 36.5 1.6 2.0 1.5 0.9 1.2 7.6 0.5 5.6 4.4 0.0 1.6 5.7 52.4 17.7 0.5 0.4 2.3 2.5 2.2 1.2 1.6 GFM1 "EFGM, EGF1, GFM, mtEF-G1" ENSG00000168827 "G elongation factor mitochondrial 1" Q96RP9 3 158644527-158695581 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034764, HPA034765, HPA061405" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA034764: AB_2674320, HPA034765: AB_10669849, HPA061405: AB_2684505" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (5.48e-3)" "unprognostic (4.48e-3)" "unprognostic (1.84e-1)" "unprognostic (3.40e-1)" "unprognostic (4.75e-2)" "unprognostic (6.05e-2)" "unprognostic (2.48e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (9.20e-4)" "unprognostic (2.79e-1)" "prognostic favorable (1.16e-7)" "unprognostic (1.62e-1)" "unprognostic (4.78e-1)" "unprognostic (3.32e-2)" "unprognostic (8.78e-2)" 26.7 25.0 12.3 21.7 13.2 24.1 27.8 18.1 21.3 14.1 16.8 30.1 24.9 17.2 20.8 24.1 13.4 17.5 39.0 13.0 15.5 43.7 49.6 18.8 20.7 14.5 13.2 12.7 26.4 40.1 12.0 25.7 15.3 19.6 31.5 46.4 21.0 21.9 63.0 15.2 19.8 20.9 13.7 16.4 23.9 23.5 14.1 16.6 32.1 60.2 20.7 23.5 12.9 15.7 92.2 55.9 25.5 32.0 41.8 30.6 34.2 42.6 49.8 75.9 57.4 73.2 58.7 73.9 54.7 39.2 32.0 55.9 62.5 47.8 84.3 40.6 33.7 56.1 34.6 34.3 48.6 76.7 35.9 37.3 55.7 43.8 41.0 17.6 50.2 43.0 71.7 50.3 67.9 56.9 49.6 30.6 55.7 97.0 29.8 49.8 28.0 132.6 51.0 38.3 48.9 42.8 63.8 96.1 79.1 19.9 132.1 60.0 28.0 46.4 21.0 69.4 74.1 82.7 61.4 138.9 41.8 65.0 52.4 18.9 19.3 13.8 22.2 27.2 28.6 17.0 19.3 23.0 23.3 16.4 22.1 23.9 3.0 25.4 22.0 11.2 17.4 18.4 12.3 13.2 18.1 21.3 13.0 15.5 14.5 13.2 15.3 13.7 14.1 15.7 31.4 19.2 19.0 17.0 26.1 21.5 26.0 20.9 20.5 57.3 23.0 11.9 54.8 22.8 18.9 12.9 31.3 31.6 20.1 22.2 11.7 19.9 15.4 12.4 20.2 36.6 19.3 29.0 39.8 25.0 17.6 20.9 22.4 14.8 19.0 17.7 22.5 61.6 29.0 15.2 43.9 24.5 30.5 20.4 21.5 7.6 22.7 21.7 17.8 18.7 33.8 27.3 16.5 22.6 43.3 20.3 10.5 17.0 19.2 21.7 22.1 37.9 25.1 51.6 13.1 21.5 23.4 34.4 31.6 20.1 21.0 30.8 22.3 41.4 28.9 22.0 GLRX3 "bA500G10.4, GLRX4, GRX3, GRX4, PICOT, TXNL2" ENSG00000108010 "Glutaredoxin 3" O76003 10 130136391-130184521 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 280.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028941 Approved NA NA 350000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA028941: AB_10601015" "unprognostic (7.11e-3)" "unprognostic (4.02e-2)" "unprognostic (1.67e-2)" "unprognostic (5.39e-3)" "unprognostic (5.66e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (9.03e-6)" "unprognostic (9.29e-2)" "unprognostic (1.13e-1)" "unprognostic (5.76e-2)" "unprognostic (1.46e-3)" "unprognostic (1.08e-3)" "prognostic unfavorable (9.24e-6)" "unprognostic (4.01e-1)" "unprognostic (1.20e-1)" "unprognostic (7.57e-2)" "unprognostic (1.11e-1)" 36.0 44.6 24.3 40.5 25.7 38.0 35.2 25.9 30.9 29.8 26.9 32.9 35.9 29.4 28.4 58.4 25.3 28.6 54.3 25.5 28.4 37.7 42.9 28.4 54.5 27.6 26.9 24.0 35.4 36.1 21.2 40.9 28.4 27.1 38.7 27.8 32.3 29.5 53.5 41.4 31.3 40.8 25.8 27.1 33.4 64.4 26.5 39.6 32.6 55.1 63.0 49.8 38.0 26.9 209.9 134.2 126.8 195.3 84.0 130.8 136.5 149.9 148.3 182.5 153.5 234.4 164.5 157.8 94.2 118.3 160.4 133.7 170.8 179.5 198.0 123.6 145.7 84.0 87.2 201.9 108.8 163.9 80.8 85.4 205.0 167.2 227.3 164.2 147.3 116.8 190.1 72.4 201.1 103.0 119.4 239.8 146.7 121.5 142.8 161.3 131.8 59.8 179.5 114.1 62.4 84.7 85.8 93.2 194.2 139.2 69.2 103.0 111.6 96.2 96.4 130.7 219.2 52.7 87.4 316.0 201.6 88.9 59.5 25.7 45.2 21.5 40.6 58.8 48.2 52.1 45.1 45.4 70.3 37.8 34.4 41.7 7.3 59.1 51.8 44.8 76.7 49.5 24.3 25.7 25.9 30.9 25.5 28.4 27.6 26.9 28.4 25.8 26.5 26.9 47.6 41.7 28.1 20.9 38.4 82.8 90.1 167.1 32.5 24.1 42.1 40.5 61.5 40.0 74.4 27.6 14.6 122.9 47.3 38.3 62.6 160.1 252.7 39.6 43.4 57.0 34.0 44.6 24.7 147.7 162.2 48.3 28.5 38.7 42.5 47.7 43.2 36.2 113.2 42.1 24.6 50.7 77.3 44.6 54.2 138.9 40.7 46.1 49.8 15.0 72.9 37.9 47.4 22.1 22.5 150.2 32.3 50.4 41.0 115.2 58.7 100.7 58.3 25.1 19.7 41.2 95.1 280.9 188.1 62.7 99.0 163.1 41.8 49.7 64.7 100.5 GMFB GMF ENSG00000197045 "Glia maturation factor beta" P60983 14 54474484-54489026 "Plasma proteins, Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 90.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002954 Approved Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA002954: AB_1078997" "unprognostic (7.93e-2)" "unprognostic (7.69e-3)" "unprognostic (4.81e-3)" "unprognostic (2.99e-2)" "unprognostic (1.12e-2)" "unprognostic (2.06e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.48e-2)" "unprognostic (1.90e-1)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "prognostic favorable (9.48e-5)" "unprognostic (1.80e-1)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (9.09e-2)" 25.2 21.8 62.8 23.5 68.8 28.8 26.0 61.6 90.4 18.6 39.8 35.0 33.5 19.3 14.0 15.8 14.2 16.5 17.2 61.4 75.6 33.6 25.8 24.2 25.3 73.0 64.5 16.1 12.8 20.1 12.3 26.5 71.4 14.8 35.2 18.4 10.7 12.9 7.0 13.7 29.5 18.2 84.0 18.4 19.0 11.1 71.9 16.2 21.9 10.2 24.4 22.3 11.4 85.3 92.7 36.9 71.8 53.2 75.8 94.5 53.9 93.2 67.9 66.2 82.1 42.6 79.4 85.2 42.4 92.0 39.5 33.4 73.7 64.0 104.4 30.9 25.4 42.5 37.4 39.9 64.7 59.9 35.5 72.0 58.8 57.1 56.0 67.9 60.8 38.4 31.4 28.8 106.1 45.7 36.8 22.9 46.4 52.1 38.9 36.9 84.7 24.4 84.4 86.3 42.4 65.5 64.6 54.4 71.4 59.0 59.8 46.4 48.1 94.9 71.9 48.7 58.4 10.4 19.4 52.0 80.0 36.3 61.5 6.8 10.2 9.1 5.0 13.3 7.0 6.6 5.9 5.1 12.6 7.8 6.2 6.6 16.1 8.0 14.0 4.4 8.5 6.2 62.8 68.8 61.6 90.4 61.4 75.6 73.0 64.5 71.4 84.0 71.9 85.3 23.3 25.6 16.2 8.1 39.3 59.9 50.2 33.6 48.9 18.4 28.0 18.0 17.3 20.0 22.6 25.8 4.2 39.3 33.7 61.8 21.5 38.7 27.3 21.5 29.5 22.2 29.9 14.5 16.8 23.3 84.5 35.1 23.9 36.1 21.6 25.4 16.8 24.5 45.4 21.9 13.6 33.6 26.4 34.6 36.4 7.5 20.2 43.0 46.2 8.4 37.8 25.7 25.7 14.1 16.5 37.3 32.1 15.8 16.9 56.0 26.0 60.5 16.4 15.4 13.1 77.0 54.5 16.0 11.4 33.5 43.8 58.3 26.2 18.8 36.2 56.2 GMPS GATD7 ENSG00000163655 "Guanine monophosphate synthase" P49915 3 155870650-155944020 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" Ligase Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 100.3" "Cell type enhanced" "Detected in all" "Early spermatids: 272.7;Late spermatids: 193.6;Spermatocytes: 171.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046630 Approved Cytosol No No 50000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA046630: AB_2679727" "unprognostic (3.89e-2)" "unprognostic (2.02e-2)" "unprognostic (1.59e-2)" "prognostic unfavorable (5.54e-5)" "unprognostic (2.30e-1)" "unprognostic (1.35e-2)" "prognostic unfavorable (8.73e-7)" "unprognostic (1.71e-2)" "unprognostic (3.52e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.58e-2)" "unprognostic (2.79e-2)" "unprognostic (2.89e-2)" "unprognostic (3.78e-1)" "unprognostic (3.55e-3)" "unprognostic (8.79e-2)" 18.8 20.7 7.2 20.0 7.7 44.6 24.1 22.7 11.0 21.2 7.9 19.7 15.8 20.6 16.0 22.1 17.1 14.0 17.9 6.8 8.5 15.9 22.6 18.2 27.0 7.8 6.8 17.0 26.4 23.1 11.5 20.8 8.3 17.4 22.5 10.1 20.9 17.5 20.0 25.0 16.7 23.4 6.3 19.2 18.0 100.3 8.0 32.3 20.3 16.7 29.4 23.3 19.9 8.8 241.0 93.1 123.0 101.1 49.0 77.0 118.9 99.8 91.6 128.2 128.8 170.5 156.2 171.7 116.1 77.1 98.1 114.6 105.7 104.2 175.0 101.1 81.8 183.2 63.7 92.8 55.9 188.5 68.7 57.3 62.9 99.4 150.5 68.2 79.9 91.3 131.7 63.8 96.8 160.1 153.9 99.4 118.5 130.4 68.3 149.2 145.8 207.5 66.3 103.5 73.3 68.0 111.0 156.0 101.8 83.9 163.6 122.3 56.9 84.4 68.5 121.0 204.3 88.8 58.5 288.5 84.8 137.4 77.0 23.7 16.1 11.5 24.7 20.2 29.1 16.0 23.6 22.3 26.1 11.6 23.3 22.3 2.2 29.3 29.5 14.2 27.1 17.5 7.2 7.7 22.7 11.0 6.8 8.5 7.8 6.8 8.3 6.3 8.0 8.8 23.8 19.2 20.2 19.6 21.5 39.9 47.4 43.9 22.8 22.0 19.5 18.5 16.4 15.7 28.4 7.3 2.1 44.1 21.6 8.3 25.4 33.8 272.7 14.3 37.5 29.9 7.2 68.5 40.9 29.5 56.2 32.4 19.9 18.4 28.6 34.0 22.1 11.6 29.9 21.9 41.6 19.7 26.4 18.5 27.1 193.6 23.0 25.2 23.2 22.5 31.7 17.8 30.9 30.2 31.6 21.3 11.9 24.8 21.9 50.6 17.8 22.8 17.3 8.7 19.7 28.6 65.2 171.2 65.5 29.0 38.2 30.8 30.4 63.2 26.8 42.4 GNB2 ENSG00000172354 "G protein subunit beta 2" P62879 7 100673567-100679174 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010032, HPA040736" Approved Supported "Plasma membrane" NA NA 940000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "CAB010032: AB_2263466, HPA040736: AB_2677106" "unprognostic (1.55e-1)" "unprognostic (5.76e-2)" "unprognostic (1.01e-3)" "unprognostic (2.76e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (3.68e-3)" "unprognostic (3.52e-1)" "unprognostic (6.58e-2)" "unprognostic (2.54e-1)" "unprognostic (9.79e-3)" "unprognostic (1.70e-1)" "unprognostic (3.75e-2)" "unprognostic (1.24e-1)" "unprognostic (3.19e-1)" "unprognostic (5.29e-2)" "unprognostic (2.98e-1)" 198.4 211.0 131.4 128.3 137.3 207.5 188.0 112.3 179.6 209.4 103.8 168.0 103.2 182.4 63.7 328.4 179.8 105.5 175.9 130.2 138.1 186.1 185.8 210.1 107.9 140.3 130.1 175.3 184.8 98.9 203.3 107.4 123.6 183.0 83.6 20.1 190.8 113.6 175.9 295.5 143.5 113.5 126.3 225.9 172.4 92.9 137.6 90.2 144.8 90.2 105.7 165.2 217.7 120.7 358.6 268.6 222.7 272.5 169.8 199.9 194.3 208.4 288.4 294.3 241.7 205.3 333.7 157.7 216.0 311.3 332.2 243.0 177.7 312.6 103.0 216.9 152.1 120.8 198.7 171.3 282.4 157.7 254.5 259.5 291.1 304.2 244.6 237.6 343.6 132.5 228.6 303.3 270.4 980.0 249.5 450.3 173.5 225.1 290.1 234.3 136.3 253.8 235.4 291.3 241.0 380.1 278.0 449.2 201.3 125.3 192.4 192.1 325.8 313.8 346.8 619.2 266.6 88.8 111.9 240.9 237.1 349.7 443.6 27.6 28.6 70.9 17.5 42.7 16.2 13.6 17.9 15.4 28.1 18.1 11.8 12.4 117.2 15.4 35.9 23.8 23.5 12.5 131.4 137.3 112.3 179.6 130.2 138.1 140.3 130.1 123.6 126.3 137.6 120.7 138.1 57.7 97.0 16.0 104.1 151.8 159.3 72.9 148.0 10.4 105.4 106.0 35.0 100.1 55.5 84.6 4.2 172.4 89.4 285.4 162.4 163.7 32.6 133.5 106.8 136.5 180.4 127.7 12.7 218.7 312.1 117.6 135.1 127.2 44.4 97.6 126.0 69.9 264.4 72.3 10.8 211.2 75.3 198.6 198.8 20.1 144.8 193.5 140.5 15.9 160.8 128.2 96.8 5.0 6.9 257.1 285.6 130.1 122.5 226.5 162.3 107.0 68.3 8.5 65.7 62.0 162.2 34.3 69.6 240.7 194.8 293.9 117.8 88.1 192.2 259.5 GNG8 ENSG00000167414 "G protein subunit gamma 8" Q9UK08 19 46634076-46634685 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.1;choroid plexus: 32.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 12.6;Langerhans cells: 5.1;Melanocytes: 32.0;monocytes: 9.5;Oligodendrocytes: 5.0;Smooth muscle cells: 9.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 6.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 10.8;T-reg: 5.7" "Group enriched" "Detected in many" 5 "B-cells: 10.8;T-cells: 5.7" "Cell line enriched" "Detected in some" 4 "SH-SY5Y: 1157.3" "Region enhanced" "Detected in all" "white matter: 20.2" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 10: Non-specific - Unknown function" "unprognostic (7.23e-4)" "unprognostic (4.96e-6)" "unprognostic (9.00e-2)" "unprognostic (1.85e-1)" "unprognostic (2.41e-1)" "prognostic favorable (2.14e-5)" "unprognostic (1.94e-1)" "unprognostic (1.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (9.60e-2)" "unprognostic (9.83e-2)" "unprognostic (5.90e-8)" "unprognostic (2.67e-2)" "unprognostic (1.70e-1)" "unprognostic (4.22e-2)" "unprognostic (4.41e-1)" 0.7 22.0 44.6 5.6 52.5 0.8 0.4 44.7 71.6 5.4 32.7 4.8 1.9 2.5 0.0 0.9 2.4 0.7 10.0 43.0 68.8 2.4 0.4 1.2 4.3 51.1 105.1 1.4 0.1 2.9 7.7 0.2 46.6 1.4 2.1 0.9 0.1 1.7 0.0 0.2 2.7 3.0 42.0 2.9 1.2 1.0 48.9 16.0 0.3 0.0 6.0 1.0 1.4 65.6 0.0 1.6 1.7 0.7 0.0 0.0 0.0 0.8 0.7 0.6 0.6 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.0 0.0 89.3 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.3 0.0 0.0 0.0 0.0 0.6 0.8 0.0 1.3 0.9 0.0 0.8 0.0 0.0 264.0 1157.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.3 0.0 0.9 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.5 0.0 0.0 10.8 2.2 1.0 1.7 0.0 0.0 0.0 5.7 4.3 44.6 52.5 44.7 71.6 43.0 68.8 51.1 105.1 46.6 42.0 48.9 65.6 0.0 0.0 0.0 1.0 1.6 0.1 0.1 0.1 0.0 0.0 0.0 0.1 12.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 5.1 3.1 0.0 2.0 32.0 0.0 9.5 0.0 0.0 1.5 5.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 9.0 0.1 0.1 0.0 0.3 0.0 0.9 0.1 0.0 0.1 GNL2 "HUMAUANTIG, Ngp-1, Nog2, Nug2" ENSG00000134697 "G protein nucleolar 2" Q13823 1 37566816-37595937 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027163, HPA060026" Approved Enhanced "Nucleoli,Nucleoli rim" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "HPA027163: AB_10601655, HPA060026: AB_2684191" "unprognostic (1.38e-2)" "unprognostic (5.23e-2)" "unprognostic (2.61e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (5.86e-9)" "unprognostic (2.28e-1)" "unprognostic (7.80e-2)" "prognostic favorable (7.89e-4)" "unprognostic (1.01e-2)" "unprognostic (8.19e-2)" "prognostic unfavorable (2.90e-11)" "unprognostic (3.36e-2)" "unprognostic (7.33e-3)" "unprognostic (3.37e-1)" "unprognostic (1.87e-1)" 27.8 22.4 11.1 24.8 12.1 49.9 30.4 12.5 13.5 21.7 13.1 22.8 17.8 22.8 24.4 26.4 20.1 19.4 21.6 10.9 12.1 19.2 31.6 22.7 26.5 13.0 12.0 20.4 20.8 20.9 19.3 23.5 12.7 18.2 25.5 11.7 23.2 14.2 50.6 29.5 18.7 24.4 12.1 19.6 21.9 30.2 13.5 26.1 16.0 29.0 32.7 35.2 21.2 14.1 66.5 33.5 63.9 66.4 49.8 57.1 102.9 98.6 68.5 89.3 90.4 92.6 75.2 107.8 62.7 73.5 50.8 60.6 105.1 80.5 121.1 62.6 83.5 108.4 66.4 74.5 66.5 143.3 73.7 36.2 72.6 122.4 144.3 42.7 65.2 47.1 146.8 74.6 87.3 58.2 77.7 85.9 165.8 48.2 65.9 81.8 114.7 121.8 75.0 70.7 76.9 71.1 74.2 73.4 73.1 93.8 52.7 82.5 53.0 59.1 83.9 127.2 138.6 69.9 67.8 185.8 68.3 113.2 77.3 23.2 28.1 24.4 22.5 36.3 26.0 28.1 21.0 24.6 39.8 21.1 21.9 21.2 2.8 33.5 35.3 29.0 28.2 21.7 11.1 12.1 12.5 13.5 10.9 12.1 13.0 12.0 12.7 12.1 13.5 14.1 18.5 16.0 48.1 6.5 29.7 63.3 84.3 37.2 27.3 8.8 17.5 14.5 21.9 12.8 63.3 7.3 10.4 37.2 27.8 18.2 27.4 52.9 54.0 27.2 31.0 28.1 17.3 17.7 6.4 62.3 49.4 40.8 23.9 29.7 48.1 29.5 11.0 18.3 32.0 6.7 5.3 27.3 24.4 17.9 29.6 13.5 23.9 27.7 8.8 8.4 31.7 21.1 25.7 3.5 5.7 51.5 21.9 19.2 32.4 68.3 15.7 18.8 54.4 9.6 0.0 44.8 34.8 46.7 45.6 29.5 52.8 46.1 28.3 20.6 27.5 56.5 GPATCH11 "CCDC75, CENP-Y, CENPY, FLJ38348" ENSG00000152133 "G-patch domain containing 11" Q8N954 2 37084451-37099244 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038231, HPA038232" Enhanced Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA038231: AB_2675904, HPA038232: AB_10675788" "unprognostic (1.28e-2)" "unprognostic (1.58e-1)" "unprognostic (2.45e-1)" "unprognostic (1.80e-1)" "unprognostic (3.88e-2)" "unprognostic (2.23e-2)" "unprognostic (4.58e-3)" "unprognostic (2.40e-2)" "unprognostic (2.44e-2)" "unprognostic (4.39e-2)" "unprognostic (1.16e-1)" "unprognostic (1.26e-1)" "unprognostic (8.64e-3)" "unprognostic (4.31e-2)" "unprognostic (4.44e-2)" "unprognostic (3.40e-2)" "unprognostic (7.16e-2)" 23.0 6.3 7.5 7.8 8.5 10.0 6.9 8.8 9.9 7.0 6.0 4.5 4.8 4.8 3.7 5.1 3.7 4.4 5.4 7.7 8.8 5.5 5.7 6.3 12.7 8.3 8.0 5.9 3.0 5.5 3.5 5.7 8.5 4.0 4.9 21.0 3.7 4.1 2.4 5.9 5.0 4.3 8.5 8.0 4.8 11.6 8.0 10.3 6.4 5.4 11.7 5.2 3.1 10.4 12.5 7.4 12.4 9.7 25.7 11.9 13.2 22.1 8.9 13.1 10.7 9.4 5.2 14.4 12.1 8.3 11.4 8.8 14.8 5.3 19.5 24.7 16.1 26.3 9.8 9.6 8.3 31.7 27.5 7.8 9.4 18.0 10.1 8.6 11.6 9.0 25.0 65.8 15.4 6.3 20.6 17.4 5.3 20.5 10.3 16.9 26.4 40.7 5.7 5.3 14.9 13.9 11.6 7.4 11.2 9.9 7.6 14.6 12.9 23.7 13.1 17.4 24.7 25.6 28.2 21.6 16.9 26.2 21.3 5.9 2.4 2.2 4.4 2.0 4.4 8.7 3.2 3.7 3.6 6.8 3.4 3.5 0.8 6.7 0.7 12.2 2.6 1.5 7.5 8.5 8.8 9.9 7.7 8.8 8.3 8.0 8.5 8.5 8.0 10.4 14.7 12.8 8.1 3.9 23.3 4.2 2.7 5.7 7.4 24.3 6.2 7.0 14.1 8.6 5.0 11.0 25.0 8.8 48.7 12.1 11.7 9.3 32.9 12.6 20.0 12.8 3.0 22.1 14.3 14.1 30.5 12.2 8.6 13.9 12.0 8.7 17.9 15.0 13.4 13.5 12.1 9.1 6.1 18.8 15.0 10.5 16.1 21.1 3.6 5.6 12.7 28.9 22.6 10.6 12.5 14.8 4.9 22.2 23.2 1.6 9.7 13.2 11.5 52.7 13.1 13.4 21.7 75.5 43.6 7.8 5.4 3.8 16.8 13.7 6.0 2.0 GPBP1L1 SP192 ENSG00000159592 "GC-rich promoter binding protein 1 like 1" Q9HC44 1 45627304-45688113 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028593 Approved Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028593: AB_10602906" "unprognostic (1.39e-1)" "unprognostic (8.41e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (6.35e-2)" "unprognostic (1.97e-3)" "unprognostic (2.42e-3)" "unprognostic (9.79e-2)" "unprognostic (3.91e-2)" "unprognostic (1.94e-3)" "unprognostic (1.12e-2)" "unprognostic (4.11e-1)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (4.51e-1)" "unprognostic (7.56e-3)" "unprognostic (6.13e-2)" 28.7 26.7 25.2 31.0 29.4 49.3 40.9 27.3 28.0 35.0 26.1 57.3 54.0 35.6 37.6 45.0 36.2 30.3 41.7 23.6 27.1 47.0 66.3 39.2 39.9 27.7 28.3 30.6 39.3 41.7 25.5 34.1 28.2 35.8 61.2 27.4 42.4 36.1 46.2 47.2 56.7 36.3 26.8 36.9 42.6 57.9 27.4 54.7 48.7 54.9 49.5 35.6 36.7 32.8 41.1 24.7 42.1 44.9 48.4 47.1 57.5 31.9 52.2 44.8 56.1 25.2 44.8 56.3 40.5 43.7 46.9 42.0 46.6 47.8 56.3 64.4 33.4 73.7 28.9 39.2 66.7 74.2 65.1 34.6 102.0 35.3 99.4 60.2 57.7 71.0 63.7 48.7 51.6 22.0 66.2 65.8 60.4 54.8 27.7 43.0 55.1 41.9 51.5 40.2 51.9 34.7 52.6 76.6 83.5 81.6 35.1 86.2 49.8 32.0 33.6 35.2 48.9 47.2 46.9 41.3 34.0 60.6 34.5 24.0 21.6 40.3 21.6 27.3 22.9 16.5 20.9 21.1 23.0 14.1 22.6 22.4 22.6 26.6 30.6 13.1 26.4 21.1 25.2 29.4 27.3 28.0 23.6 27.1 27.7 28.3 28.2 26.8 27.4 32.8 43.3 60.9 24.4 54.5 45.1 64.9 41.2 28.3 59.2 23.5 51.3 33.5 46.9 41.5 34.3 60.7 35.5 26.2 47.5 96.8 50.9 33.0 23.4 38.1 32.2 38.6 38.3 62.1 48.5 38.9 33.7 25.4 44.9 47.5 59.6 24.3 37.5 81.3 25.0 37.0 49.0 67.2 32.6 49.9 51.6 17.6 20.5 46.1 23.2 70.3 41.3 18.2 45.3 50.8 93.8 51.2 57.0 21.4 36.6 62.8 75.5 58.7 33.0 32.9 19.7 22.4 42.0 78.9 75.3 71.7 67.8 45.4 47.1 27.7 68.6 78.2 GSPT1 "eRF3a, ETF3A, GST1" ENSG00000103342 "G1 to S phase transition 1" P15170 16 11868128-11916082 "Plasma proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Protein biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052488, HPA074588" Approved Approved Vesicles,Cytosol NA NA 210000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol Vesicles "HPA052488: AB_2681849, HPA074588: " "unprognostic (4.13e-2)" "unprognostic (1.66e-1)" "prognostic favorable (2.10e-5)" "unprognostic (1.64e-1)" "unprognostic (2.05e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (7.94e-4)" "unprognostic (2.38e-1)" "unprognostic (2.31e-1)" "unprognostic (1.74e-1)" "unprognostic (1.41e-3)" "unprognostic (1.65e-1)" "prognostic favorable (3.06e-5)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.61e-3)" "unprognostic (3.13e-2)" 60.8 57.5 22.3 49.5 24.7 76.3 46.0 24.4 33.3 42.0 27.4 56.0 33.8 34.5 46.6 67.9 30.1 35.2 53.4 23.9 24.5 53.6 76.3 47.7 55.4 25.0 23.1 33.3 62.2 62.7 27.5 50.0 26.2 47.8 59.6 35.3 41.0 41.8 127.0 43.5 34.3 46.9 25.0 40.2 49.8 68.7 23.1 56.3 57.7 97.8 82.0 85.7 39.6 29.3 220.1 212.9 116.1 161.0 164.2 169.3 167.5 238.0 245.9 187.1 185.4 153.1 197.8 295.7 303.9 207.5 130.1 164.3 297.8 220.3 312.9 142.4 153.6 202.0 163.1 325.5 137.9 258.7 103.5 133.5 170.0 212.0 288.3 122.4 210.4 146.2 331.7 148.7 220.0 211.2 219.8 134.0 232.9 163.0 120.1 256.4 200.5 345.6 184.7 189.3 186.4 99.6 342.0 256.3 144.2 164.3 222.4 122.6 163.3 206.8 129.5 151.5 190.3 146.6 233.2 253.8 145.4 258.1 128.5 1.4 5.8 7.7 6.3 11.1 8.8 7.9 8.1 7.7 7.0 6.5 8.2 8.1 1.9 7.2 9.9 3.8 10.5 4.3 22.3 24.7 24.4 33.3 23.9 24.5 25.0 23.1 26.2 25.0 23.1 29.3 69.4 76.9 160.2 39.5 92.3 242.2 232.0 47.1 170.8 47.7 95.0 61.6 123.4 57.2 69.1 86.5 50.1 76.1 94.5 88.1 103.7 58.9 94.9 109.0 95.6 74.4 66.6 328.5 61.6 63.4 118.3 77.2 81.1 153.9 24.7 93.2 43.5 77.9 75.2 52.2 47.0 107.2 32.6 60.8 116.3 51.6 47.8 80.9 64.0 35.6 50.1 43.6 25.7 38.7 42.9 73.0 66.9 47.4 166.2 271.0 38.3 120.3 52.7 41.5 59.2 94.6 123.0 138.3 83.5 198.5 257.7 102.1 132.1 128.1 114.1 270.4 GSTA5 ENSG00000182793 "Glutathione S-transferase alpha 5" Q7RTV2 6 52831655-52840843 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 10 "Smooth muscle cells: 23.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004342, HPA048934, HPA053817" Uncertain Approved Cytosol NA NA "Cluster 10: Non-specific - Unknown function" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (1.97e-2)" "unprognostic (2.83e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 2.2 0.4 0.0 0.0 0.0 23.6 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 GTF3C4 "KAT12, TFIIIC90" ENSG00000125484 "General transcription factor IIIC subunit 4" Q9UKN8 9 132670035-132694953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transcription "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069369 Supported Nucleoplasm,Mitochondria No No "Cluster 40: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Mitochondria "HPA069369: AB_2686130" "unprognostic (7.02e-2)" "unprognostic (9.01e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-2)" "unprognostic (1.58e-1)" "unprognostic (1.76e-1)" "unprognostic (4.77e-1)" "unprognostic (1.92e-2)" "prognostic favorable (2.99e-4)" "unprognostic (1.65e-1)" "unprognostic (1.23e-1)" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" 4.9 4.4 4.3 4.6 5.0 6.9 8.4 9.2 4.3 7.3 3.6 5.3 3.9 6.6 5.5 6.7 6.6 5.2 5.8 4.5 5.2 6.0 5.3 5.7 5.0 3.4 4.8 10.3 6.1 9.4 3.2 6.4 3.7 6.2 5.4 5.5 7.3 5.7 5.8 9.8 3.6 6.2 3.6 4.5 5.8 8.3 5.6 8.1 9.5 8.0 6.6 5.0 3.8 3.8 15.2 21.7 25.8 22.5 12.3 14.4 20.0 15.1 18.4 19.6 14.4 25.4 10.9 22.7 9.8 18.6 18.1 33.8 39.8 23.6 21.1 15.4 19.1 19.0 28.9 10.8 12.8 28.6 12.4 11.4 17.6 20.4 26.1 11.6 16.8 15.1 32.7 11.4 14.0 24.6 17.8 13.3 33.1 22.2 21.4 17.6 31.1 20.6 14.3 12.5 36.3 24.6 25.9 25.8 15.9 15.8 35.4 12.1 17.8 32.9 18.7 15.1 21.6 4.9 12.3 25.1 13.5 17.8 20.7 0.0 0.3 0.2 0.5 0.3 0.4 0.5 0.4 0.6 0.2 0.4 0.5 0.5 0.3 0.5 0.2 0.5 0.4 0.2 4.3 5.0 9.2 4.3 4.5 5.2 3.4 4.8 3.7 3.6 5.6 3.8 9.9 19.2 11.5 2.3 7.8 30.7 6.9 6.9 21.6 15.5 19.1 14.7 14.6 1.5 6.7 3.7 14.6 7.5 9.0 6.6 7.9 8.3 6.5 21.5 26.2 11.6 13.1 8.2 3.2 6.3 7.5 13.0 8.6 17.7 1.3 17.1 10.0 8.6 6.3 20.2 3.1 8.1 10.2 7.6 9.3 3.7 19.0 6.3 3.6 1.9 7.1 11.9 7.2 1.0 2.1 5.8 7.0 19.2 10.7 11.6 3.8 6.6 16.2 16.9 0.0 18.8 10.9 16.7 13.8 22.1 40.1 6.4 8.8 18.2 9.0 6.4 HCFC1 "CFF, HCF-1, HCF1, HFC1, MGC70925, MRX3, PPP1R89, VCAF" ENSG00000172534 "Host cell factor C1" P51610 X 153947557-153971818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction" "Chromatin regulator" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078588 Supported Supported Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA078588: " "unprognostic (2.05e-3)" "unprognostic (2.92e-2)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (2.64e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (4.31e-6)" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "prognostic favorable (9.62e-5)" "unprognostic (1.45e-1)" "unprognostic (1.29e-3)" "unprognostic (1.99e-2)" "unprognostic (2.12e-1)" "unprognostic (1.73e-2)" "unprognostic (2.80e-1)" 18.8 25.5 18.4 15.5 16.9 40.2 17.1 14.9 22.5 21.9 10.3 29.7 11.4 33.6 8.5 25.1 24.3 7.6 23.1 19.7 14.1 22.1 23.8 21.6 19.0 16.6 16.8 25.5 21.1 11.4 33.9 8.7 15.2 23.5 7.0 7.2 19.2 12.8 28.4 18.6 25.3 11.1 13.6 32.8 24.8 17.9 16.8 26.1 21.1 10.5 12.1 23.6 19.8 17.1 45.3 57.7 38.4 48.9 15.8 11.2 56.3 18.2 14.0 21.1 19.1 61.5 29.8 81.6 45.3 23.6 34.6 36.4 41.8 29.7 11.0 43.6 49.2 49.0 47.7 48.8 10.8 60.9 77.8 17.6 19.1 36.8 15.9 12.7 22.7 58.2 69.4 50.2 15.0 63.0 84.6 78.2 50.0 29.4 35.1 97.5 31.6 49.3 16.0 41.4 42.5 46.2 33.7 34.4 19.4 18.4 31.7 54.4 30.2 39.9 49.0 35.0 59.4 79.1 117.0 100.2 32.5 58.6 38.6 0.9 2.1 0.9 3.0 3.1 2.1 2.4 2.4 2.3 2.4 2.4 2.4 3.4 0.4 1.5 2.2 4.2 1.7 2.3 18.4 16.9 14.9 22.5 19.7 14.1 16.6 16.8 15.2 13.6 16.8 17.1 19.1 19.2 17.8 7.5 21.9 16.6 13.4 15.5 20.5 21.0 24.6 18.7 35.9 20.0 13.6 12.9 14.6 16.5 26.8 20.1 3.9 17.4 0.6 16.7 18.4 21.2 19.2 39.9 8.4 16.5 21.3 17.7 19.9 21.6 3.8 25.0 15.7 29.5 21.3 20.2 8.3 23.2 8.2 35.2 13.8 1.8 17.4 26.0 5.4 9.4 28.6 13.6 17.5 8.0 7.2 19.5 13.3 21.8 32.0 25.7 12.6 8.8 13.4 12.4 6.6 21.8 21.2 11.3 25.0 28.9 13.9 15.9 22.8 14.3 23.9 20.5 HDHD2 DKFZP564D1378 ENSG00000167220 "Haloacid dehalogenase like hydrolase domain containing 2" Q9H0R4 18 47107408-47150500 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040697, CAB045978, HPA059818" Approved Approved Vesicles NA NA 240000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB045978: AB_11124418, HPA040697: AB_2677084, HPA059818: AB_2684132" "unprognostic (3.22e-1)" "unprognostic (6.32e-2)" "unprognostic (9.95e-2)" "unprognostic (7.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.58e-1)" "unprognostic (3.11e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-2)" "unprognostic (5.35e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "prognostic favorable (3.52e-5)" "unprognostic (1.95e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (1.17e-1)" 13.7 26.3 29.1 10.5 31.0 10.5 17.0 37.2 33.4 10.9 27.3 17.2 13.4 11.8 16.0 14.3 16.2 11.9 27.2 28.3 31.5 23.9 30.2 13.5 19.6 34.2 31.8 14.2 17.9 27.0 15.6 11.6 35.2 17.6 16.5 22.1 14.0 17.1 15.5 11.7 13.7 13.5 31.2 13.5 15.8 11.4 31.9 28.1 26.4 24.1 21.2 13.1 10.0 37.5 14.1 9.1 34.5 16.9 20.6 28.4 9.6 15.8 15.3 24.9 25.0 4.7 11.1 23.0 13.4 17.7 11.3 12.2 19.0 21.2 35.3 19.2 17.6 22.1 15.0 23.5 28.2 31.1 19.6 23.4 25.5 14.0 31.3 27.1 21.0 37.2 22.8 26.3 32.6 19.0 29.2 19.6 33.9 11.9 9.3 28.1 22.0 31.2 31.4 21.5 31.2 26.0 15.0 10.6 19.5 23.7 16.0 42.7 15.2 18.9 15.2 5.4 11.5 33.1 16.9 19.9 23.3 32.1 18.8 21.4 24.7 19.7 20.7 22.9 21.8 27.3 21.5 20.5 23.9 26.7 27.1 21.6 2.3 30.5 23.3 15.8 24.2 21.4 29.1 31.0 37.2 33.4 28.3 31.5 34.2 31.8 35.2 31.2 31.9 37.5 8.8 16.0 18.2 21.5 16.9 7.1 11.1 10.7 13.6 22.5 17.7 10.5 13.1 15.7 14.0 11.0 14.6 25.0 9.7 15.6 72.4 18.9 1.9 11.0 8.5 11.5 13.8 13.9 28.9 17.9 15.0 11.0 12.8 6.4 7.6 15.6 13.9 28.1 21.7 45.4 29.2 16.2 14.2 20.3 15.0 2.7 17.7 15.0 16.0 20.6 22.7 53.1 14.4 36.7 45.4 16.4 19.3 23.7 9.7 17.5 16.0 57.7 16.4 27.0 19.7 15.1 19.7 20.2 35.1 13.1 6.0 19.7 12.2 29.8 21.6 13.0 HEATR6 "ABC1, FLJ22087" ENSG00000068097 "HEAT repeat containing 6" Q6AI08 17 60041008-60078922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 64.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030789, HPA062157" Uncertain Approved Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA030789: AB_10601660, HPA062157: AB_2684700" "unprognostic (1.98e-1)" "unprognostic (7.95e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (2.03e-4)" "unprognostic (4.22e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.02e-6)" "unprognostic (2.24e-1)" "unprognostic (2.86e-1)" "unprognostic (1.97e-1)" "unprognostic (6.81e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (6.73e-4)" "unprognostic (5.01e-2)" "unprognostic (1.81e-1)" "unprognostic (5.50e-2)" "unprognostic (2.11e-1)" 4.5 7.2 5.3 2.1 6.0 3.1 4.3 6.8 5.9 6.7 4.4 7.4 1.8 7.1 3.2 4.6 6.6 1.9 5.1 5.1 5.3 4.1 3.6 5.0 3.0 6.2 5.4 7.7 5.1 3.4 7.3 2.7 6.2 5.7 2.3 5.2 5.2 3.5 6.0 5.5 6.1 2.7 5.4 7.2 4.9 4.9 5.8 3.0 4.6 2.4 2.2 6.5 5.2 7.8 4.8 13.0 9.5 7.5 5.1 9.1 6.9 4.5 8.9 8.8 9.7 5.2 3.6 1.8 7.8 8.0 7.1 4.9 5.6 6.0 11.9 4.1 7.2 9.3 8.8 9.7 5.6 7.0 10.1 7.1 8.8 6.4 7.6 9.5 4.7 6.0 5.9 5.1 6.6 64.6 8.9 3.6 5.9 3.9 8.7 3.2 16.9 5.8 5.7 7.1 5.4 13.7 4.6 1.6 6.6 8.2 7.9 5.6 4.5 8.9 15.0 8.2 8.4 6.5 7.1 0.1 7.6 5.1 6.9 2.4 3.4 3.4 3.4 5.4 3.2 8.2 2.5 2.5 6.0 4.3 3.3 2.6 0.5 3.0 5.6 2.9 2.9 2.7 5.3 6.0 6.8 5.9 5.1 5.3 6.2 5.4 6.2 5.4 5.8 7.8 4.6 12.8 6.3 9.4 8.0 0.9 2.8 6.2 6.2 11.1 3.1 5.0 9.2 2.8 8.1 7.3 10.4 5.7 5.0 1.1 3.9 4.8 1.0 4.8 9.1 5.1 6.7 3.0 13.1 3.3 3.4 7.4 6.6 4.3 11.4 8.8 4.2 2.8 4.6 6.7 13.7 1.5 4.1 5.6 2.6 0.7 3.4 8.5 1.8 15.9 15.3 8.8 7.2 16.6 25.3 2.9 1.0 11.3 3.3 1.7 1.5 3.3 10.5 6.6 6.6 6.5 15.4 5.1 7.7 3.6 2.3 2.1 7.6 10.1 3.1 1.2 HMGA2 "BABL, HMGIC, LIPO" ENSG00000149948 "High mobility group AT-hook 2" P52926 12 65824460-65966291 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, DNA condensation, Growth regulation, Mitosis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.9;testis: 3.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 16.0;Early spermatids: 18.4;Glandular and luminal cells: 17.3;Granulosa cells: 29.7;Pancreatic endocrine cells: 19.9;Smooth muscle cells: 33.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 324.4;hTERT-RPE1: 232.6;SuSa: 216.1" "CAB017809, HPA039076" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim" "CAB017809: , HPA039076: AB_2676335" "unprognostic (2.39e-1)" "unprognostic (6.00e-2)" "unprognostic (2.08e-1)" "unprognostic (3.68e-3)" "unprognostic (5.21e-3)" "prognostic unfavorable (4.79e-4)" "unprognostic (4.05e-3)" "unprognostic (6.17e-3)" "unprognostic (6.71e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-6)" "unprognostic (3.33e-2)" "unprognostic (4.55e-5)" "unprognostic (4.22e-2)" "unprognostic (2.53e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (2.86e-4)" 0.4 0.0 0.3 0.3 0.2 4.9 0.2 0.7 0.5 1.1 0.0 2.1 1.3 0.4 0.0 0.3 1.2 0.3 0.1 0.2 0.1 0.2 0.2 0.1 0.1 0.4 0.2 0.6 0.9 0.0 0.4 0.2 0.2 0.0 2.4 0.5 0.1 0.1 1.5 0.4 1.0 0.1 0.1 0.1 1.1 3.8 0.2 0.2 0.6 0.2 0.1 0.1 0.1 0.4 47.9 21.4 324.4 45.8 15.0 82.0 0.1 148.5 68.5 26.0 25.8 28.1 19.8 0.0 92.3 7.0 120.0 20.5 54.2 129.3 123.8 0.2 56.2 0.2 0.7 169.3 8.4 4.7 0.4 62.7 8.0 55.2 98.4 232.6 105.0 0.2 0.1 0.6 149.9 0.2 0.4 27.8 190.3 4.6 89.2 12.7 16.1 0.1 68.9 0.3 0.0 0.0 0.1 0.1 85.0 216.1 0.5 0.7 120.8 89.5 26.9 71.2 45.3 0.2 0.2 0.4 112.0 0.3 21.4 1.4 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.3 0.6 0.1 0.0 0.0 0.3 0.2 0.7 0.5 0.2 0.1 0.4 0.2 0.2 0.1 0.2 0.4 0.0 0.0 1.1 5.9 0.2 0.0 3.6 16.0 2.8 0.0 0.1 0.1 1.7 0.0 3.0 0.0 0.0 0.8 0.0 5.0 0.0 2.5 18.4 10.4 0.8 0.6 0.0 7.4 0.8 0.8 0.5 2.3 3.1 17.3 0.0 29.7 0.7 0.0 9.0 0.0 0.9 5.1 4.1 0.0 0.0 9.0 0.3 0.7 0.0 0.0 0.0 0.0 1.0 0.0 0.9 19.9 4.5 0.0 0.4 5.5 4.0 0.3 7.3 0.0 0.0 1.1 33.7 13.5 0.6 0.3 0.1 0.8 0.3 0.3 8.4 1.1 HNRNPA2B1 HNRPA2B1 ENSG00000122566 "Heterogeneous nuclear ribonucleoprotein A2/B1" P22626 7 26171151-26201529 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Transport" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001666, HPA005812, CAB012403, HPA065537" Supported Enhanced Nucleoplasm "Intracellular and membrane" NA NA 11000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB012403: , HPA001666: AB_1850836, HPA005812: AB_2667441, HPA065537: AB_2685507" "unprognostic (1.19e-1)" "unprognostic (4.45e-1)" "unprognostic (2.33e-1)" "unprognostic (6.39e-2)" "unprognostic (5.64e-2)" "unprognostic (8.04e-3)" "prognostic unfavorable (1.03e-6)" "unprognostic (1.25e-2)" "unprognostic (9.12e-3)" "unprognostic (4.35e-3)" "unprognostic (1.31e-1)" "prognostic unfavorable (5.12e-4)" "prognostic unfavorable (8.01e-5)" "unprognostic (6.74e-2)" "unprognostic (3.36e-2)" "unprognostic (2.02e-1)" "unprognostic (1.56e-2)" 367.0 421.3 101.3 151.4 105.4 77.6 314.1 110.9 140.3 403.5 106.4 381.8 124.8 404.3 116.1 417.6 376.3 62.4 463.6 99.7 106.4 530.8 388.5 364.9 184.1 106.4 105.0 527.8 350.2 80.8 337.6 118.9 108.2 300.8 127.5 131.1 325.1 79.2 764.9 280.5 419.0 84.2 102.3 447.5 353.4 370.5 105.4 174.8 367.2 92.0 172.5 339.9 360.8 111.7 202.5 101.8 491.6 312.7 110.7 117.5 249.6 255.8 110.7 149.6 183.6 159.8 338.5 210.2 104.2 180.1 218.8 300.0 196.3 268.7 288.5 74.9 191.2 232.6 309.9 212.1 72.9 374.6 359.4 123.6 192.4 156.3 253.3 194.6 161.1 273.9 210.9 250.4 280.4 229.1 216.5 817.2 320.7 81.7 117.7 239.5 122.1 159.3 287.0 335.8 190.7 245.6 203.5 291.8 127.7 393.6 326.3 359.7 222.0 193.2 265.6 184.6 253.7 367.0 296.0 308.7 149.9 453.8 316.5 0.0 1.7 1.3 4.8 1.0 4.0 2.7 3.0 0.8 0.8 0.8 2.7 2.6 0.6 3.3 0.8 1.6 1.0 0.5 101.3 105.4 110.9 140.3 99.7 106.4 106.4 105.0 108.2 102.3 105.4 111.7 717.8 487.2 591.0 194.6 667.5 738.5 797.7 793.2 560.5 469.4 361.0 361.3 702.1 316.0 665.8 343.9 298.2 971.6 707.7 435.1 461.8 568.0 128.2 465.8 640.8 600.5 491.4 683.2 123.3 452.2 939.9 602.7 449.6 591.1 644.7 680.5 333.4 382.8 613.1 312.9 147.2 533.1 496.4 388.5 681.9 150.0 411.0 640.3 393.1 157.4 572.0 545.4 484.1 198.0 320.6 438.2 438.7 390.0 751.0 520.4 428.4 506.8 608.0 547.0 440.4 599.4 726.5 596.9 490.6 573.8 600.5 1082.8 701.7 652.2 541.4 632.1 HNRNPA3 HNRPA3 ENSG00000170144 "Heterogeneous nuclear ribonucleoprotein A3" P51991 2 177212563-177223958 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001666, HPA005812, HPA066381" Supported Enhanced Nucleoplasm NA NA 1800000 "Cluster 6: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA001666: AB_1850836, HPA005812: AB_2667441, HPA066381: AB_2685666" "unprognostic (2.85e-2)" "prognostic favorable (4.87e-4)" "unprognostic (2.21e-1)" "unprognostic (1.26e-1)" "unprognostic (2.14e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.95e-5)" "unprognostic (2.46e-1)" "unprognostic (3.15e-3)" "unprognostic (2.80e-3)" "unprognostic (3.65e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (9.57e-7)" "unprognostic (6.95e-2)" "unprognostic (3.04e-1)" "unprognostic (4.55e-2)" "unprognostic (1.10e-2)" 162.9 119.0 101.6 210.8 104.5 235.2 144.2 107.5 114.6 183.8 98.8 185.3 129.2 180.1 178.1 244.6 164.3 75.4 118.4 93.7 124.1 193.6 144.3 175.2 232.9 111.8 103.1 208.2 141.4 130.5 137.5 158.5 106.9 141.0 194.7 181.7 138.8 118.1 136.3 179.9 152.3 164.2 103.8 174.7 143.1 175.8 108.6 308.3 176.0 93.0 304.8 153.3 189.2 108.1 657.6 432.9 934.3 469.8 248.2 221.2 717.8 489.3 235.7 382.8 358.5 885.1 337.4 1315.9 366.5 388.4 518.3 370.6 944.2 616.7 712.9 609.6 556.2 996.1 620.3 1727.6 264.8 1064.7 584.0 249.8 288.3 569.9 422.1 217.9 537.3 587.4 723.1 414.3 492.1 891.1 746.9 444.4 507.3 762.5 405.0 947.2 790.1 414.2 547.9 1227.6 545.1 484.7 729.6 228.1 316.4 700.8 325.6 652.5 582.2 476.3 540.4 338.0 719.0 387.6 759.5 1117.2 305.4 699.5 320.0 8.9 21.2 10.8 25.0 22.6 20.2 21.2 20.0 22.0 23.4 20.4 17.5 18.1 8.2 23.5 23.0 37.8 25.9 14.5 101.6 104.5 107.5 114.6 93.7 124.1 111.8 103.1 106.9 103.8 108.6 108.1 274.8 166.7 255.1 84.5 277.4 351.8 429.6 442.1 224.8 192.8 155.2 135.1 64.2 114.4 302.7 160.0 98.0 512.7 368.9 200.7 121.3 257.2 47.2 296.5 387.2 289.7 275.0 288.6 56.9 273.8 563.0 231.4 184.0 343.0 278.1 222.6 196.7 165.0 342.7 148.0 70.5 315.0 193.3 221.0 372.5 44.0 204.7 258.3 192.1 73.1 311.1 187.1 232.8 65.9 88.6 276.1 184.0 209.5 336.6 288.9 136.8 156.7 257.8 164.4 151.2 319.3 461.9 362.8 208.3 331.1 330.5 496.0 307.9 214.1 310.7 382.6 HNRNPAB "ABBP1, FLJ40338, HNRPAB" ENSG00000197451 "Heterogeneous nuclear ribonucleoprotein A/B" Q99729 5 178204533-178211163 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046688 Approved Enhanced Nucleoplasm NA NA 460000 "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA046688: AB_10964924" "unprognostic (2.23e-1)" "unprognostic (6.21e-2)" "unprognostic (2.61e-2)" "unprognostic (1.96e-2)" "unprognostic (8.69e-2)" "unprognostic (1.17e-1)" "unprognostic (1.22e-3)" "unprognostic (4.09e-2)" "unprognostic (6.17e-3)" "prognostic favorable (9.79e-4)" "unprognostic (9.12e-3)" "unprognostic (4.23e-2)" "prognostic unfavorable (1.35e-7)" "unprognostic (3.47e-2)" "unprognostic (1.82e-1)" "unprognostic (3.53e-1)" "unprognostic (2.08e-1)" 86.7 103.2 33.2 92.5 34.9 139.7 63.9 35.6 37.0 66.0 37.3 144.7 98.2 75.5 43.8 122.0 64.4 51.1 83.1 32.4 39.1 91.9 88.3 69.1 95.7 36.9 35.4 56.7 55.4 76.2 46.2 64.0 36.9 59.8 119.0 27.1 68.1 54.0 119.0 115.4 88.9 74.4 35.5 79.9 85.5 38.2 36.9 117.0 52.0 58.7 102.7 122.3 72.7 38.5 347.4 282.5 424.1 414.7 153.8 134.6 613.2 378.5 174.3 296.9 317.2 525.4 251.8 555.2 340.3 204.7 361.1 223.2 373.1 516.7 363.8 865.9 439.5 349.8 223.7 325.1 153.7 446.1 285.6 134.0 239.2 267.3 266.8 122.3 270.3 218.4 290.1 245.7 302.0 934.2 542.6 429.7 389.5 354.0 401.7 436.3 255.6 329.8 254.2 364.8 389.5 302.4 295.2 407.9 278.8 264.0 244.7 270.7 244.0 359.7 305.2 256.2 527.8 285.4 360.2 649.3 145.2 488.2 298.8 3.2 4.4 15.7 5.1 7.0 5.7 5.9 4.1 6.0 4.4 5.2 3.9 4.7 0.8 5.8 7.5 10.9 4.8 2.2 33.2 34.9 35.6 37.0 32.4 39.1 36.9 35.4 36.9 35.5 36.9 38.5 124.7 32.1 41.0 4.6 115.4 281.6 212.1 42.7 243.0 26.5 129.6 141.3 45.9 41.5 42.7 49.7 18.8 106.3 148.5 251.2 50.9 118.9 9.3 112.4 225.6 107.1 119.2 273.2 3.5 151.7 208.9 110.1 167.7 124.7 44.5 102.0 53.6 101.2 101.0 16.8 4.3 219.0 48.8 67.0 129.9 11.1 74.0 109.9 67.6 8.4 56.2 34.7 76.2 3.5 6.1 204.2 138.2 88.0 179.6 275.0 90.5 116.8 25.8 28.3 78.9 149.7 173.6 81.6 122.4 362.5 339.8 114.4 129.7 238.1 247.9 235.5 HNRNPCL1 HNRPCL1 ENSG00000179172 "Heterogeneous nuclear ribonucleoprotein C like 1" O60812 1 12847377-12848720 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.9;Langerhans cells: 1.7;Smooth muscle cells: 2.7;Suprabasal keratinocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Non-specific - Unknown function" "unprognostic (2.13e-1)" "unprognostic (3.57e-1)" "unprognostic (2.57e-1)" "unprognostic (4.40e-1)" "unprognostic (1.10e-1)" "unprognostic (7.05e-2)" "unprognostic (3.23e-2)" "unprognostic (1.15e-1)" "unprognostic (4.11e-1)" "unprognostic (1.05e-1)" "unprognostic (6.03e-1)" "unprognostic (1.71e-1)" "unprognostic (8.28e-2)" "unprognostic (8.64e-3)" "unprognostic (8.88e-2)" "unprognostic (3.43e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.8 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.1 2.7 0.1 0.1 0.0 1.7 0.3 0.1 0.0 0.0 0.5 HNRNPCL2 HNRNPCP5 ENSG00000275774 "Heterogeneous nuclear ribonucleoprotein C like 2" B2RXH8 1 13115488-13116854 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Non-specific - Unknown function" "unprognostic (9.41e-2)" "unprognostic (2.20e-1)" "unprognostic (7.42e-2)" "unprognostic (3.84e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 HNRNPD "AUF1, HNRPD" ENSG00000138668 "Heterogeneous nuclear ribonucleoprotein D" Q14103 4 82352498-82374503 "Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004911 Supported Enhanced Nucleoplasm NA NA 1100000 "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA004911: AB_1078250" "unprognostic (9.60e-3)" "unprognostic (1.01e-2)" "unprognostic (9.09e-2)" "unprognostic (2.65e-1)" "unprognostic (1.74e-1)" "unprognostic (1.77e-1)" "unprognostic (1.03e-3)" "unprognostic (1.75e-2)" "unprognostic (6.23e-2)" "unprognostic (2.06e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-2)" "unprognostic (1.40e-2)" "unprognostic (5.93e-2)" "unprognostic (1.08e-1)" "unprognostic (2.81e-1)" "unprognostic (1.31e-2)" 147.4 114.7 61.9 207.3 61.6 377.7 155.5 83.7 89.1 167.3 68.4 153.6 169.8 176.6 137.1 155.5 152.0 98.7 122.7 60.7 81.0 144.2 140.6 129.0 290.2 61.0 61.7 180.6 146.7 134.1 117.0 167.8 59.2 138.6 164.4 188.1 147.1 125.4 169.7 151.8 177.2 140.1 54.1 184.6 164.6 97.7 61.6 335.1 122.8 103.4 310.7 159.8 145.7 69.2 661.7 257.5 1073.5 344.2 138.9 179.1 508.9 506.2 384.6 566.7 484.9 461.1 565.7 1332.6 357.1 343.3 301.9 318.2 863.8 376.6 883.9 250.1 450.8 957.4 345.2 630.7 282.1 1283.9 475.2 221.0 164.7 459.6 459.5 290.2 521.2 637.3 1076.0 446.6 487.7 254.3 1569.2 887.2 897.8 487.2 236.1 1149.2 1089.0 556.7 478.0 394.8 540.9 583.3 496.5 426.0 262.2 497.0 319.7 504.9 443.7 435.3 595.3 339.7 661.7 472.5 403.1 1516.3 334.6 651.6 508.9 26.1 11.3 12.4 13.3 12.5 15.1 20.3 16.2 17.0 13.5 13.9 17.5 14.6 13.6 14.1 14.1 23.6 19.7 7.2 61.9 61.6 83.7 89.1 60.7 81.0 61.0 61.7 59.2 54.1 61.6 69.2 152.4 102.5 143.5 63.6 128.0 261.3 227.8 139.0 111.0 128.4 124.6 121.9 202.6 125.8 149.0 112.2 62.6 299.7 163.4 71.6 70.5 204.3 35.3 136.2 218.9 162.3 146.6 182.6 65.3 210.6 355.2 134.7 98.4 204.5 92.3 191.5 114.9 114.4 156.6 107.7 72.9 158.9 85.5 125.6 172.7 21.8 124.8 134.5 90.7 63.7 169.3 187.8 130.7 84.9 105.8 157.4 56.7 102.3 151.0 208.3 91.3 80.9 115.7 118.8 111.7 185.5 154.5 106.7 133.7 147.0 229.7 272.0 133.6 149.1 169.3 228.8 HNRNPF HNRPF ENSG00000169813 "Heterogeneous nuclear ribonucleoprotein F" P52597 10 43385617-43409166 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA016884, HPA069667" Supported Enhanced Nucleoplasm NA Yes 2500000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA016884: AB_1856444, HPA069667: AB_2686166" "unprognostic (9.93e-2)" "unprognostic (2.26e-2)" "unprognostic (1.81e-1)" "unprognostic (3.65e-2)" "unprognostic (6.39e-2)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.85e-4)" "unprognostic (1.51e-2)" "unprognostic (6.37e-2)" "unprognostic (6.33e-3)" "unprognostic (4.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.95e-2)" "unprognostic (3.77e-3)" "unprognostic (3.35e-1)" "unprognostic (3.71e-1)" "unprognostic (2.22e-1)" 114.6 77.7 43.3 133.9 48.6 161.3 102.9 49.8 47.9 86.8 65.2 124.5 134.2 78.3 58.9 114.9 119.4 88.9 63.7 40.2 45.9 94.4 173.2 97.6 181.4 52.4 51.4 87.3 87.5 73.1 50.5 113.6 51.5 90.8 118.9 80.4 85.2 74.8 93.6 104.5 130.7 89.1 49.2 123.5 118.0 84.0 49.4 193.3 72.7 79.6 182.8 160.0 81.8 58.3 292.1 302.9 184.2 280.7 220.5 239.5 269.1 222.5 371.0 305.6 358.2 285.5 394.7 581.8 139.2 242.0 179.3 401.7 496.8 363.6 249.5 245.6 297.2 371.2 178.6 370.9 271.4 550.5 360.9 293.2 282.4 237.6 434.6 177.1 266.4 281.3 382.0 256.2 234.2 453.4 542.5 300.5 139.5 439.1 252.4 449.0 172.7 276.8 314.9 442.7 226.1 226.8 226.6 410.4 344.3 199.2 457.4 265.3 200.4 140.1 264.4 231.8 356.8 228.5 415.8 352.6 227.1 520.0 139.7 205.5 234.9 227.2 247.0 269.2 301.0 238.9 256.6 273.3 251.8 200.7 213.8 204.0 152.2 287.9 253.6 140.6 315.8 460.5 43.3 48.6 49.8 47.9 40.2 45.9 52.4 51.4 51.5 49.2 49.4 58.3 223.8 134.6 102.8 13.4 206.9 336.0 336.5 204.9 189.5 51.4 156.8 126.4 66.3 157.3 147.9 112.2 47.9 292.9 201.7 164.7 176.1 218.6 360.1 203.8 153.3 176.6 126.8 199.6 10.8 142.2 414.8 157.0 154.9 147.0 116.1 106.9 127.5 222.3 226.0 48.8 12.0 230.1 164.8 193.3 181.7 92.7 146.0 178.5 99.6 24.4 213.0 116.9 219.4 16.6 32.7 161.4 152.1 117.8 163.3 280.8 189.7 233.1 242.0 163.6 98.6 179.7 278.1 184.5 167.3 210.2 330.5 210.4 229.9 126.3 238.8 314.0 HNRNPK "CSBP, HNRPK, TUNP" ENSG00000165119 "Heterogeneous nuclear ribonucleoprotein K" P61978 9 83968083-83980616 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, Ribonucleoprotein, RNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004435, HPA007644, CAB016225, HPA044105" Supported Enhanced Nucleoplasm NA NA 7100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004435: AB_627734, CAB016225: , HPA007644: AB_1079077, HPA044105: AB_2678812" "unprognostic (4.84e-2)" "unprognostic (4.69e-1)" "unprognostic (1.15e-2)" "unprognostic (8.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.83e-3)" "prognostic unfavorable (6.68e-5)" "unprognostic (3.46e-3)" "unprognostic (8.11e-2)" "unprognostic (1.47e-1)" "unprognostic (8.85e-3)" "unprognostic (2.81e-2)" "unprognostic (2.76e-3)" "unprognostic (2.23e-3)" "unprognostic (6.50e-2)" "unprognostic (4.59e-1)" "unprognostic (2.82e-1)" 283.6 308.1 186.1 326.2 197.1 637.3 265.3 202.4 236.6 264.5 227.4 270.2 287.0 297.0 227.3 276.8 269.7 243.8 275.8 188.8 220.3 279.2 346.8 240.4 401.9 203.1 187.8 317.5 247.4 350.8 198.2 325.8 203.0 251.3 277.5 342.2 242.2 251.4 315.3 256.1 282.9 287.6 205.7 298.3 250.1 183.4 194.4 548.5 297.2 312.9 423.7 351.2 230.7 241.0 926.1 624.2 1048.4 625.7 492.2 540.7 840.0 634.1 785.0 778.2 726.4 527.0 641.2 1087.2 425.8 671.1 673.8 689.5 1061.5 772.9 941.8 753.7 624.2 765.1 511.9 754.6 648.7 958.6 726.5 554.6 577.4 665.6 876.1 583.7 806.1 605.5 792.8 541.4 776.4 809.0 1198.4 652.1 934.7 929.3 599.3 1030.2 835.0 727.6 760.3 747.6 677.1 802.6 669.6 703.8 645.5 721.8 698.6 801.6 665.8 537.9 631.7 552.7 844.2 564.7 795.5 784.6 514.3 762.6 779.5 582.0 438.9 559.2 302.2 419.8 378.9 347.8 346.6 348.7 457.5 324.4 354.8 327.2 546.1 477.9 429.1 270.8 457.4 1012.5 186.1 197.1 202.4 236.6 188.8 220.3 203.1 187.8 203.0 205.7 194.4 241.0 354.7 205.1 270.0 58.4 398.4 506.0 540.7 421.5 313.0 180.9 281.6 203.3 195.0 230.2 322.4 263.0 89.6 585.3 379.9 288.1 395.2 448.2 43.4 326.2 329.0 331.7 387.0 447.9 45.9 368.3 738.5 323.4 233.9 384.2 336.8 300.0 260.9 356.6 388.4 156.5 51.2 379.2 307.2 352.9 412.9 45.4 334.6 333.4 327.3 58.1 448.9 362.5 338.8 71.9 116.2 397.0 282.7 321.2 281.0 353.3 260.0 416.7 308.1 182.6 276.1 340.9 479.7 345.9 241.7 309.5 448.7 728.5 368.6 334.9 406.9 453.2 HNRNPM "CEAR, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1" ENSG00000099783 "Heterogeneous nuclear ribonucleoprotein M" P52272 19 8444767-8489114 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016113, HPA024344" Supported Enhanced Nucleoplasm NA NA 440000 "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB016113: AB_627739, HPA024344: AB_1850879" "unprognostic (2.12e-1)" "unprognostic (8.59e-2)" "unprognostic (2.51e-2)" "unprognostic (2.06e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (1.80e-6)" "unprognostic (2.44e-1)" "unprognostic (2.59e-2)" "unprognostic (6.91e-3)" "unprognostic (4.70e-3)" "unprognostic (7.34e-2)" "unprognostic (3.62e-2)" "unprognostic (1.22e-3)" "unprognostic (1.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.73e-1)" 97.2 83.9 55.6 126.3 63.0 230.9 94.4 66.0 63.8 104.4 61.4 108.3 98.4 113.8 57.1 126.4 92.5 54.4 89.1 51.6 61.0 92.4 89.4 90.6 141.3 60.7 59.1 121.9 84.1 90.5 71.5 87.5 60.8 76.6 91.9 127.7 93.0 75.4 148.6 106.5 100.8 88.0 57.2 110.5 90.9 78.1 59.8 166.3 93.2 62.1 156.0 93.2 101.5 69.3 477.5 315.7 580.8 236.3 131.4 145.2 373.7 279.3 208.5 340.3 256.9 452.4 141.4 697.4 363.4 254.3 242.4 286.3 603.3 349.4 425.1 437.5 501.0 620.1 312.2 439.8 136.3 640.0 317.4 150.5 173.4 289.2 119.9 100.0 309.7 256.3 632.3 193.6 273.3 324.3 617.2 556.8 505.1 258.2 381.1 687.8 508.1 330.5 179.6 452.9 320.7 356.8 469.5 250.4 278.8 276.8 299.0 378.4 362.9 294.5 357.4 313.6 529.2 285.4 560.8 791.4 221.7 511.4 329.1 21.3 78.4 48.0 91.2 93.4 91.7 69.6 79.0 91.6 86.6 61.4 84.3 83.0 20.0 86.0 71.8 86.3 87.6 94.5 55.6 63.0 66.0 63.8 51.6 61.0 60.7 59.1 60.8 57.2 59.8 69.3 157.1 128.2 189.0 48.6 154.1 166.3 204.8 240.8 105.9 199.6 143.8 125.1 92.1 118.7 240.8 117.7 70.9 272.8 170.3 95.5 97.8 237.4 13.2 150.6 194.7 164.3 190.4 211.5 43.3 273.1 304.4 141.7 76.0 190.2 267.4 136.3 111.4 148.5 174.4 138.0 46.5 154.6 138.4 127.2 139.8 18.3 113.4 137.7 110.3 59.0 212.5 186.1 219.4 60.8 79.8 202.2 102.9 142.1 118.7 92.7 77.8 106.0 193.1 213.6 210.4 194.1 231.2 182.3 150.6 106.3 137.0 262.4 168.7 125.4 183.3 131.3 HNRNPR "hnRNP-R, HNRPR" ENSG00000125944 "Heterogeneous nuclear ribonucleoprotein R" O43390 1 23303771-23344336 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011687, HPA026092" Supported Enhanced Nucleoplasm NA NA 470000 "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB011687: AB_2295532, HPA026092: AB_1850885" "unprognostic (1.86e-1)" "unprognostic (2.12e-1)" "unprognostic (1.45e-2)" "unprognostic (1.17e-1)" "unprognostic (1.92e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.32e-5)" "unprognostic (2.29e-2)" "unprognostic (1.67e-2)" "unprognostic (3.01e-1)" "unprognostic (1.15e-3)" "unprognostic (3.28e-2)" "unprognostic (7.65e-2)" "unprognostic (1.37e-1)" "unprognostic (4.95e-2)" "unprognostic (4.14e-2)" "unprognostic (4.12e-1)" 51.1 47.9 18.4 48.7 21.6 56.6 49.0 26.0 22.9 55.0 22.3 44.7 33.6 66.1 25.8 54.9 52.6 29.0 40.4 18.1 22.2 43.8 27.2 47.6 58.0 20.2 19.6 61.6 34.0 42.3 33.9 50.0 21.6 35.0 43.2 40.2 46.7 31.8 55.9 51.2 46.7 44.7 20.1 41.9 38.9 31.0 19.2 71.9 43.5 27.7 60.0 48.3 50.1 26.8 161.7 103.9 200.9 123.5 70.0 73.6 103.6 102.7 118.0 178.3 123.0 73.2 113.4 202.3 52.1 141.4 88.9 89.5 211.0 143.9 208.5 142.3 161.4 192.5 131.0 121.9 68.4 224.2 125.1 74.8 86.7 141.5 113.4 73.3 112.9 153.0 185.4 139.9 119.2 98.3 268.3 71.6 111.6 105.3 103.4 196.9 186.5 144.1 96.5 88.7 137.3 132.6 141.8 116.0 88.7 109.5 98.6 102.6 121.0 102.6 133.4 123.8 129.5 81.3 149.0 276.8 71.9 200.7 117.7 21.7 35.9 44.9 49.0 47.2 51.7 41.4 45.0 47.7 45.8 41.6 48.0 45.5 12.8 53.9 48.1 30.0 58.4 46.6 18.4 21.6 26.0 22.9 18.1 22.2 20.2 19.6 21.6 20.1 19.2 26.8 112.0 118.6 109.1 29.0 132.7 127.6 207.1 139.0 95.6 127.8 89.1 78.0 72.3 84.4 138.0 88.3 43.8 253.0 125.8 60.2 92.0 126.6 22.9 110.5 183.8 129.3 116.4 150.4 28.6 126.5 274.4 135.3 92.2 146.2 172.0 171.4 61.8 73.1 106.6 126.2 32.6 107.8 138.4 77.7 92.4 17.2 120.9 98.8 83.6 36.5 147.7 159.9 112.3 63.3 60.6 125.2 64.1 116.6 144.3 208.5 59.6 76.9 114.5 111.1 85.5 159.1 170.2 170.4 148.3 136.4 129.9 206.7 136.5 157.3 116.8 182.4 HPR ENSG00000261701 "Haptoglobin-related protein" P00739 16 72063148-72077246 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 811.9" "Group enriched" "Detected in some" 14 "Hepatocytes: 503.0;Smooth muscle cells: 128.8" "Cancer enriched" "Detected in some" 53 "liver cancer: 185.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 50.6" HPA047750 Supported Approved Vesicles "Secreted to blood" NA NA 49000000000 55000000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA047750: AB_2680146" "unprognostic (2.43e-1)" "unprognostic (4.69e-2)" "unprognostic (5.97e-3)" "unprognostic (2.42e-1)" "unprognostic (2.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.66e-1)" "unprognostic (8.21e-2)" "unprognostic (2.30e-1)" "unprognostic (3.44e-6)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" 5.5 0.5 14.1 0.2 15.3 0.1 2.0 13.9 16.7 1.2 11.3 1.2 0.6 0.3 0.4 0.3 1.3 0.7 137.2 13.7 14.3 4.0 811.9 1.5 0.7 14.4 14.3 2.0 0.6 0.0 0.3 0.0 13.6 1.6 0.1 0.8 0.3 0.3 1.7 0.6 1.1 0.1 12.8 0.3 1.7 1.9 15.2 0.2 1.1 0.2 0.1 0.4 1.9 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.6 2.2 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.2 0.0 0.1 0.0 0.6 0.6 0.0 14.1 15.3 13.9 16.7 13.7 14.3 14.4 14.3 13.6 12.8 15.2 13.1 0.0 0.0 7.5 2.3 0.4 0.1 0.0 0.9 0.0 0.1 0.0 0.0 22.4 12.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.8 0.0 5.3 0.2 0.2 0.0 2.6 0.0 0.0 0.0 1.1 10.8 503.0 0.0 0.0 0.2 0.0 2.0 12.8 0.0 2.8 9.9 0.0 0.0 0.0 0.0 4.9 0.0 0.0 1.2 0.0 0.0 5.3 0.0 0.0 0.0 13.0 0.2 0.1 0.0 6.1 128.8 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 HSPA4 "HS24/P52, HSPH2" ENSG00000170606 "Heat shock protein family A (Hsp70) member 4" P34932 5 133052013-133106449 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010023, CAB025529" Uncertain Approved Nucleoplasm,Cytosol NA NA 14000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "CAB025529: , HPA010023: AB_1851206" "unprognostic (2.54e-2)" "unprognostic (3.59e-1)" "unprognostic (2.91e-2)" "unprognostic (2.62e-1)" "unprognostic (5.30e-2)" "unprognostic (2.52e-3)" "prognostic unfavorable (4.13e-4)" "unprognostic (2.31e-3)" "unprognostic (2.90e-1)" "unprognostic (2.40e-1)" "unprognostic (1.53e-1)" "unprognostic (2.85e-1)" "unprognostic (4.44e-3)" "unprognostic (2.54e-1)" "unprognostic (1.09e-1)" "unprognostic (4.05e-2)" "unprognostic (1.41e-1)" 31.3 36.9 33.8 41.0 37.2 35.6 26.9 38.1 63.7 26.6 52.0 31.8 26.6 27.5 29.3 62.0 26.8 27.8 50.8 39.8 43.8 44.3 47.2 26.3 47.4 37.6 41.0 21.3 29.7 43.5 24.0 37.7 45.0 26.3 34.7 104.0 27.9 26.9 57.7 26.1 26.0 35.3 38.4 28.7 26.6 62.8 40.3 40.2 39.7 41.7 60.9 48.4 23.7 48.2 160.8 215.8 147.6 241.7 137.5 114.6 267.3 171.0 127.8 162.1 199.2 408.0 163.2 264.4 175.2 165.8 382.6 138.9 259.4 282.9 232.7 122.9 148.3 195.4 136.5 225.7 109.6 122.6 163.8 115.1 117.3 209.7 136.3 92.9 157.2 126.5 207.9 79.6 179.8 141.4 173.5 91.0 202.4 123.8 98.7 156.6 180.4 140.2 146.7 207.4 117.0 96.0 163.4 84.4 234.6 273.5 124.3 118.5 139.0 146.8 210.8 127.1 206.1 90.7 215.2 199.9 125.5 198.7 149.2 29.5 22.6 24.9 18.1 35.8 21.5 34.2 16.6 19.0 27.7 42.0 17.1 16.2 14.7 22.9 27.1 10.5 18.0 18.5 33.8 37.2 38.1 63.7 39.8 43.8 37.6 41.0 45.0 38.4 40.3 48.2 30.5 64.1 47.0 12.4 74.8 41.8 116.8 25.5 52.9 58.9 30.3 26.8 113.1 28.6 47.3 22.0 54.2 67.3 38.5 42.9 27.4 48.4 68.7 54.7 48.5 40.8 47.2 46.9 24.2 49.9 66.1 45.3 38.2 46.1 54.6 66.9 19.6 32.9 64.3 35.3 24.8 34.4 36.7 28.2 40.9 31.9 23.3 50.7 30.2 21.5 55.0 60.1 22.6 18.6 24.2 50.1 24.9 25.9 66.5 61.5 27.7 49.7 60.7 152.4 26.3 41.8 85.1 107.4 101.0 71.7 41.8 87.2 58.2 68.0 39.4 69.7 HTRA2 "OMI, PARK13, PRSS25" ENSG00000115317 "HtrA serine peptidase 2" O43464 2 74529725-74533332 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" Apoptosis "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 118.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004004, HPA006602, HPA027366" Uncertain Supported Mitochondria NA NA 260000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "CAB004004: AB_326421, HPA006602: AB_2667622, HPA027366: AB_1851301" "unprognostic (3.09e-1)" "unprognostic (4.06e-2)" "unprognostic (2.82e-1)" "unprognostic (2.58e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (7.77e-8)" "unprognostic (2.12e-3)" "unprognostic (4.18e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-2)" "unprognostic (8.15e-2)" "unprognostic (7.23e-3)" "unprognostic (4.03e-1)" "unprognostic (1.73e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-2)" 11.4 8.6 8.1 8.1 8.7 11.1 6.8 9.1 9.7 7.1 7.7 6.4 6.9 6.9 1.0 6.0 7.1 4.7 9.4 8.1 8.3 8.1 6.5 6.6 7.8 8.6 8.5 10.9 7.4 9.4 4.7 6.3 8.3 4.8 3.3 2.5 8.5 5.3 14.5 5.4 7.9 5.3 8.2 9.9 6.4 6.2 9.6 9.1 6.8 9.0 4.8 6.5 5.8 9.2 19.1 14.7 14.7 12.6 21.3 9.0 30.1 17.0 10.3 10.3 7.0 21.1 8.5 16.6 12.9 10.7 26.0 19.7 12.0 19.6 2.4 34.0 31.4 33.3 10.8 19.0 19.8 15.3 22.4 9.9 13.7 18.4 19.5 18.4 14.2 23.5 43.9 24.9 9.7 14.1 22.0 31.1 10.0 22.8 37.7 15.8 37.0 17.1 9.6 8.2 15.1 17.7 8.9 18.6 32.5 7.3 9.3 13.2 10.6 19.2 19.7 33.4 35.3 29.5 10.2 9.8 13.6 23.4 13.0 5.8 7.0 4.0 4.8 5.7 5.8 11.0 4.8 4.1 8.6 9.9 4.3 4.1 2.6 5.0 4.5 4.5 5.7 5.5 8.1 8.7 9.1 9.7 8.1 8.3 8.6 8.5 8.3 8.2 9.6 9.2 30.7 0.0 4.8 6.2 27.3 20.6 19.7 33.8 13.6 12.0 17.4 21.7 0.9 21.5 15.7 11.0 0.0 24.7 25.8 12.5 35.2 32.4 30.8 11.9 18.1 29.6 9.0 118.5 6.3 17.7 37.8 23.3 11.2 12.9 27.3 20.9 22.9 12.7 31.5 10.1 6.3 12.3 20.3 10.7 19.4 48.9 24.8 14.6 30.2 2.8 26.3 20.2 30.9 5.5 7.5 26.1 16.8 20.7 36.0 21.3 24.8 36.8 13.5 16.3 26.3 18.7 56.5 64.3 43.3 16.7 22.0 20.2 20.6 27.1 20.0 15.7 IFT20 ENSG00000109083 "Intraflagellar transport 20" Q8IY31 17 28328325-28335489 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 245.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021376 Approved Approved Microtubules NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Microtubules "HPA021376: AB_1851460" "unprognostic (1.29e-1)" "unprognostic (2.35e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (8.65e-4)" "unprognostic (1.13e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (8.02e-2)" "unprognostic (4.86e-3)" "unprognostic (2.42e-1)" "unprognostic (2.48e-2)" "unprognostic (6.19e-3)" "prognostic unfavorable (5.09e-7)" "unprognostic (1.67e-1)" "unprognostic (2.29e-1)" "unprognostic (2.59e-2)" "unprognostic (4.71e-3)" 24.9 32.9 26.6 14.7 26.9 77.0 26.8 27.0 46.1 23.4 29.1 37.0 28.8 20.9 39.2 18.8 22.6 22.2 19.7 26.9 28.3 33.5 41.4 22.3 20.7 27.7 27.6 21.6 116.1 25.5 45.2 24.1 27.0 29.9 20.0 26.7 41.2 20.5 9.5 17.6 28.0 20.0 27.5 24.9 42.4 50.1 27.0 22.8 29.2 7.5 19.9 27.9 19.6 27.9 27.3 39.0 25.2 20.7 74.2 75.2 24.2 47.2 58.0 28.9 45.5 59.6 12.7 13.4 24.8 59.8 17.5 29.1 16.9 35.1 41.8 55.0 72.5 8.0 39.7 26.7 72.7 34.1 16.0 57.6 46.4 24.8 39.9 48.2 46.1 26.6 24.2 32.8 23.0 38.2 30.7 26.8 16.9 82.4 21.8 14.4 32.6 35.4 46.2 26.7 31.7 46.2 31.3 64.3 74.8 43.6 41.0 38.2 51.3 16.9 25.8 25.3 25.9 49.6 44.8 17.1 61.6 24.6 25.1 53.7 67.7 52.6 38.6 50.6 44.8 43.2 39.2 38.6 78.1 51.6 39.8 34.7 71.1 36.8 49.0 56.1 45.8 53.7 26.6 26.9 27.0 46.1 26.9 28.3 27.7 27.6 27.0 27.5 27.0 27.9 42.1 38.5 55.8 17.9 36.7 37.0 38.0 63.0 34.7 63.3 74.6 68.3 6.1 47.1 51.5 51.5 60.5 73.0 47.4 30.7 140.8 60.8 245.4 79.8 40.3 47.3 62.6 25.7 31.3 113.2 82.6 47.4 32.1 39.5 23.5 34.2 38.2 48.6 54.2 57.2 36.5 69.5 40.7 47.8 69.4 53.4 60.3 49.6 32.0 7.5 72.8 37.4 42.2 24.6 30.7 68.0 29.9 57.6 57.8 45.9 127.8 98.0 102.6 78.3 78.9 33.5 67.0 164.8 53.0 25.7 42.8 81.4 35.9 59.6 43.1 49.5 ILKAP "DKFZP434J2031, FLJ10181, PPM1O" ENSG00000132323 "ILK associated serine/threonine phosphatase" Q9H0C8 2 238170402-238203708 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004752, HPA056099" Uncertain Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA004752: AB_1851753, HPA056099: AB_2797255" "unprognostic (1.50e-1)" "unprognostic (1.62e-1)" "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (1.60e-1)" "unprognostic (3.07e-2)" "unprognostic (3.88e-2)" "unprognostic (1.37e-3)" "unprognostic (7.03e-2)" "prognostic unfavorable (9.89e-6)" "unprognostic (6.24e-2)" "unprognostic (6.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.20e-1)" 20.5 17.4 24.3 15.1 25.6 29.0 19.5 26.5 26.9 26.2 22.3 30.8 14.6 25.1 15.3 23.2 23.4 8.7 24.2 23.8 24.9 26.0 26.2 18.6 20.5 24.9 24.2 24.5 20.6 13.1 26.5 12.9 24.1 25.2 12.9 13.0 17.3 14.5 41.4 22.4 23.3 16.1 23.9 25.9 21.4 23.1 24.6 17.9 23.9 18.3 18.1 26.6 21.8 27.4 40.5 25.6 36.9 36.3 28.1 18.6 37.9 41.5 27.9 40.9 35.4 23.7 20.9 25.8 10.5 30.1 48.8 33.8 48.1 34.4 41.2 46.6 49.8 66.7 26.0 52.7 43.3 43.7 50.3 19.6 23.3 43.6 43.6 20.2 31.1 34.0 52.4 16.1 35.4 48.1 43.4 58.0 34.8 37.4 25.9 52.6 75.6 23.7 30.4 18.8 54.1 26.7 28.2 29.6 68.9 27.9 23.3 43.7 28.9 39.7 36.7 53.5 45.1 28.6 31.4 46.7 32.5 47.3 34.3 43.4 19.8 27.1 28.2 25.6 25.4 24.7 24.9 26.4 27.7 24.0 28.8 22.9 7.3 24.8 21.4 20.9 30.7 23.0 24.3 25.6 26.5 26.9 23.8 24.9 24.9 24.2 24.1 23.9 24.6 27.4 27.7 12.8 22.0 43.8 35.4 27.0 29.1 30.8 25.0 28.9 19.4 21.6 23.1 17.2 19.6 25.8 29.2 41.2 51.5 22.4 43.0 27.9 8.1 17.1 20.6 21.5 19.1 64.2 37.7 28.5 43.7 26.7 29.0 16.1 33.7 43.5 22.1 19.2 34.4 38.7 33.2 24.0 16.2 17.0 22.0 12.6 28.3 24.0 30.2 25.3 34.0 25.1 57.7 36.7 72.2 24.8 16.2 29.3 33.6 29.7 24.1 33.4 19.3 28.6 32.9 29.2 47.4 54.4 70.8 29.2 28.7 40.4 36.6 23.0 27.4 23.5 IMMP1L "FLJ25059, IMMP1" ENSG00000148950 "Inner mitochondrial membrane peptidase subunit 1" Q96LU5 11 31432401-31509645 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038372, HPA058308" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038372: AB_10669643, HPA058308: AB_2732620" "unprognostic (2.39e-1)" "unprognostic (1.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.17e-2)" "unprognostic (9.67e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (7.97e-4)" "unprognostic (7.59e-2)" "unprognostic (4.66e-3)" "unprognostic (5.15e-3)" "prognostic favorable (6.72e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-2)" "unprognostic (4.66e-1)" "unprognostic (4.52e-2)" "unprognostic (1.37e-2)" "unprognostic (1.04e-3)" 11.7 15.6 42.8 6.4 43.7 11.1 19.3 45.5 66.4 13.5 41.8 12.7 8.6 11.5 29.8 11.7 10.4 5.1 26.2 42.8 42.3 27.2 18.6 8.9 9.5 42.4 42.0 17.5 16.4 17.9 23.3 6.9 42.3 14.3 10.0 37.7 11.8 14.1 50.0 12.5 9.5 10.7 42.9 10.8 15.1 16.7 43.0 24.8 13.2 42.1 13.1 10.9 12.6 43.5 22.9 26.9 95.6 21.0 14.9 9.9 15.3 19.9 8.7 16.2 11.7 21.0 17.5 20.7 18.7 15.9 32.5 25.8 37.6 28.8 23.8 24.9 52.6 29.4 45.5 32.3 15.8 29.6 19.9 8.0 27.1 8.7 19.2 29.5 17.5 48.8 38.0 23.2 15.9 28.2 48.5 48.9 15.8 114.6 26.3 41.1 72.2 20.6 54.6 26.2 22.5 27.0 32.5 11.6 32.5 61.9 37.1 35.1 2.6 15.3 27.2 16.2 42.2 17.2 58.2 47.5 24.9 24.9 18.5 21.9 3.0 32.2 28.9 3.4 26.3 34.1 25.3 29.5 8.1 32.1 32.0 39.8 0.8 37.3 3.0 40.2 35.4 13.6 42.8 43.7 45.5 66.4 42.8 42.3 42.4 42.0 42.3 42.9 43.0 43.5 29.2 35.3 14.6 30.7 22.4 18.2 26.8 60.5 12.0 30.6 44.6 55.1 56.8 18.6 26.8 60.7 33.3 36.3 17.6 21.7 119.3 17.0 39.8 30.2 16.9 19.4 56.5 47.4 40.6 24.5 32.5 19.7 20.9 33.8 22.7 22.7 18.2 45.0 21.3 43.7 48.0 30.6 52.9 7.7 11.4 10.5 13.4 9.4 8.8 24.4 10.3 85.3 30.9 51.3 60.7 15.8 26.7 20.7 22.0 26.0 18.6 98.4 28.9 38.5 32.9 19.1 51.0 61.6 23.0 19.6 27.3 23.7 24.2 16.2 34.7 26.2 IMPDH2 ENSG00000178035 "Inosine monophosphate dehydrogenase 2" P12268 3 49024325-49029447 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" "DNA-binding, Oxidoreductase, RNA-binding" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001400, CAB020717" Approved Supported "Cytosol,Rods & Rings" NA NA 340000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "Rods & Rings" "CAB020717: , HPA001400: AB_1079139" "unprognostic (2.09e-2)" "unprognostic (2.91e-1)" "unprognostic (5.96e-2)" "unprognostic (1.20e-1)" "unprognostic (7.31e-3)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.30e-1)" "unprognostic (2.65e-1)" "unprognostic (2.17e-1)" "unprognostic (5.44e-2)" "unprognostic (4.24e-2)" "unprognostic (1.30e-1)" "unprognostic (3.85e-1)" "unprognostic (5.80e-2)" "unprognostic (2.24e-1)" "unprognostic (4.47e-2)" 109.1 89.3 42.1 68.0 43.0 105.3 188.6 44.2 41.6 169.6 37.3 100.8 75.3 113.5 48.2 169.0 199.3 64.9 70.0 39.5 45.2 67.5 63.5 83.3 78.7 46.9 43.2 331.0 313.9 55.7 65.0 81.0 46.6 97.6 121.2 22.0 87.9 66.4 272.8 180.0 74.1 100.9 45.1 68.6 93.4 36.1 43.8 95.9 75.1 124.4 122.0 119.7 137.5 48.9 271.8 150.6 201.6 211.3 309.2 558.4 200.6 180.8 298.2 425.5 361.0 265.8 235.2 485.7 128.2 220.7 119.5 183.1 433.6 369.8 371.1 119.9 135.3 362.2 205.0 257.8 264.4 388.4 139.0 497.7 403.1 414.6 756.5 331.8 313.5 337.7 221.7 266.2 354.1 213.4 327.0 258.9 269.0 255.4 300.2 143.5 218.4 487.9 251.7 166.2 130.2 128.9 198.1 216.5 341.3 170.2 277.3 166.1 151.4 181.0 347.7 449.5 468.8 253.3 193.3 227.3 214.1 421.9 188.1 21.8 27.8 10.7 43.6 46.8 81.9 79.7 58.4 47.7 51.1 79.6 84.9 71.6 10.9 60.5 41.6 38.0 40.2 45.2 42.1 43.0 44.2 41.6 39.5 45.2 46.9 43.2 46.6 45.1 43.8 48.9 40.5 64.1 60.9 3.9 92.2 202.7 255.0 253.8 229.9 16.1 202.7 231.8 32.3 74.4 122.4 36.8 14.6 327.3 34.5 51.1 80.3 133.6 2.7 49.0 120.5 60.9 60.7 112.5 2.9 187.1 280.6 104.4 70.3 51.2 66.1 98.0 52.8 24.9 95.3 15.2 4.1 124.4 114.0 55.9 105.4 6.7 123.3 50.0 88.9 1.0 67.3 26.5 24.7 4.0 5.2 108.8 70.8 71.1 64.6 160.1 47.4 92.0 53.7 15.8 39.5 149.4 215.1 22.6 62.5 195.7 195.6 314.0 52.3 166.8 266.5 157.2 INTS12 "INT12, PHF22, SBBI22" ENSG00000138785 "Integrator complex subunit 12" Q96CB8 4 105682627-105895986 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035772, HPA041814" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies, Plasma membrane" "HPA035772: AB_10671109, HPA041814: AB_2677687" "unprognostic (5.30e-2)" "unprognostic (4.54e-2)" "unprognostic (1.84e-3)" "unprognostic (1.78e-1)" "unprognostic (3.68e-2)" "unprognostic (2.58e-3)" "prognostic unfavorable (2.67e-4)" "unprognostic (3.95e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-3)" "unprognostic (3.00e-2)" "unprognostic (3.48e-2)" "unprognostic (5.93e-3)" "unprognostic (3.62e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (2.06e-1)" 15.2 11.1 12.8 10.9 13.3 30.4 20.2 14.9 18.0 14.1 12.0 14.7 18.1 14.6 17.8 13.5 13.2 12.7 18.9 12.4 14.9 18.7 22.6 16.4 14.0 12.3 14.0 11.6 12.6 17.2 10.3 11.9 12.5 18.1 15.6 17.2 14.4 13.4 26.5 14.0 15.5 17.1 12.7 12.6 15.0 13.9 14.3 19.9 19.9 26.0 17.0 15.6 11.2 13.7 24.4 12.8 28.5 29.8 27.5 32.6 20.8 28.2 29.1 34.7 35.9 18.1 26.9 34.9 15.4 31.9 26.9 13.8 31.7 40.7 42.8 36.9 19.0 26.3 19.6 25.7 44.3 46.7 23.0 31.0 51.7 34.5 51.4 22.5 32.3 29.1 39.8 26.7 37.8 25.6 55.3 28.9 12.4 35.3 19.5 28.0 31.0 26.8 32.5 16.3 30.7 24.6 19.8 32.6 31.0 22.4 26.4 27.2 21.3 22.7 23.3 24.8 30.5 40.8 40.9 52.2 25.3 31.5 46.0 64.0 23.7 38.5 25.7 26.6 28.9 33.0 29.4 29.4 27.7 32.1 30.6 28.3 17.9 42.9 28.3 42.6 34.8 21.9 12.8 13.3 14.9 18.0 12.4 14.9 12.3 14.0 12.5 12.7 14.3 13.7 19.0 12.8 11.8 14.0 15.1 11.0 11.8 25.8 15.4 10.5 12.1 11.7 18.7 11.5 12.9 3.7 10.4 16.1 13.6 8.3 43.0 25.2 35.8 8.1 11.2 16.8 6.0 15.6 13.8 20.3 18.6 10.8 8.6 8.7 24.7 9.9 11.7 9.3 17.8 10.1 15.7 5.2 30.5 9.0 9.5 28.4 12.2 9.8 7.2 9.4 15.5 14.0 21.6 27.2 19.1 20.5 6.8 8.2 18.9 14.2 16.5 17.1 6.2 9.3 0.0 12.9 20.1 13.4 16.2 14.1 10.4 18.3 13.0 14.9 10.2 11.0 INTS5 "INT5, KIAA1698" ENSG00000185085 "Integrator complex subunit 5" Q6P9B9 11 62646848-62653302 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046181, HPA056915" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA046181: , HPA056915: AB_2683276" "unprognostic (2.87e-1)" "unprognostic (9.51e-2)" "unprognostic (9.11e-2)" "unprognostic (9.70e-2)" "unprognostic (2.71e-1)" "unprognostic (6.41e-2)" "unprognostic (1.97e-2)" "unprognostic (5.52e-2)" "unprognostic (1.90e-1)" "unprognostic (5.95e-2)" "unprognostic (2.33e-1)" "unprognostic (5.09e-2)" "prognostic favorable (8.44e-5)" "unprognostic (7.08e-3)" "unprognostic (2.97e-2)" "unprognostic (3.36e-1)" "unprognostic (1.35e-2)" 8.3 9.3 5.5 8.0 5.7 5.4 8.5 5.7 6.0 10.1 5.5 9.1 7.8 11.4 5.3 12.1 12.9 5.8 8.1 5.7 5.4 8.6 12.6 7.7 10.6 6.0 5.6 10.2 10.3 8.8 6.6 6.0 5.8 9.2 5.8 2.8 11.7 6.9 13.9 12.4 8.8 8.3 5.5 10.5 9.5 6.1 5.8 8.3 7.8 8.3 9.2 9.1 8.7 5.8 17.5 21.1 12.2 11.4 23.5 17.1 11.4 14.2 14.4 18.7 13.4 15.1 19.0 33.1 25.0 18.0 15.5 26.7 24.6 32.9 9.0 20.8 17.1 17.2 15.8 10.2 21.2 19.0 15.7 19.9 25.3 20.1 17.1 14.2 18.8 14.5 26.6 18.9 16.3 35.8 22.0 22.1 18.7 20.7 26.4 22.2 16.5 39.9 14.3 11.3 16.4 13.8 15.9 22.0 22.2 8.6 31.3 12.9 15.7 17.8 13.6 27.6 12.9 26.5 21.9 23.8 20.5 14.3 17.2 4.3 5.3 3.9 6.4 3.5 10.1 4.1 5.9 5.7 5.5 5.0 6.9 6.4 1.9 7.7 4.1 5.5 4.6 6.3 5.5 5.7 5.7 6.0 5.7 5.4 6.0 5.6 5.8 5.5 5.8 5.8 5.0 3.2 7.8 2.3 8.8 2.2 7.1 8.2 4.6 7.5 6.6 6.3 3.1 7.2 9.3 3.7 0.0 14.0 10.7 4.8 11.7 12.0 6.4 5.7 5.0 6.9 6.7 2.5 2.0 10.6 9.3 5.2 4.1 4.4 8.9 6.7 9.7 11.5 8.7 10.1 2.1 7.9 8.2 7.0 3.1 8.9 6.5 4.3 0.0 1.9 12.6 10.4 8.2 2.0 1.0 9.7 2.2 7.9 7.3 8.5 8.7 10.2 13.2 3.8 13.1 5.1 8.6 10.8 11.3 5.4 4.1 19.8 6.8 9.1 7.6 5.9 INTS8 "C8orf52, FLJ20530, INT8, MGC131633" ENSG00000164941 "Integrator complex subunit 8" Q75QN2 8 94813311-94881746 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057299 Approved Approved Nucleoplasm Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA057299: AB_2683403" "unprognostic (1.08e-2)" "unprognostic (3.12e-2)" "unprognostic (1.28e-1)" "unprognostic (5.86e-2)" "unprognostic (1.96e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (2.54e-6)" "unprognostic (3.07e-2)" "unprognostic (6.87e-2)" "unprognostic (9.77e-3)" "unprognostic (4.84e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.24e-1)" "unprognostic (5.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.96e-2)" 8.8 7.5 4.4 13.9 4.8 15.5 8.1 8.3 6.4 14.5 6.9 12.8 7.8 13.2 4.2 10.5 9.5 7.3 10.2 4.8 6.4 6.4 8.9 7.5 17.4 5.7 4.4 11.4 13.5 10.1 8.3 9.4 4.6 10.4 14.8 10.3 11.0 8.7 12.6 10.3 10.6 13.6 4.0 9.9 10.6 30.6 6.3 20.6 8.8 12.0 13.6 10.4 10.4 6.1 52.4 31.9 49.2 43.4 17.7 41.7 25.5 27.5 26.0 35.7 33.0 22.5 38.0 52.3 25.2 20.7 44.3 31.5 61.3 29.2 47.6 58.1 28.8 45.7 19.3 22.1 21.1 24.6 31.7 17.1 13.5 34.7 29.6 40.8 40.1 35.1 44.4 38.9 22.0 34.5 53.7 20.4 28.1 114.9 55.8 42.7 19.7 29.0 30.0 26.6 34.6 18.4 26.8 7.7 24.1 40.3 37.3 31.6 28.1 16.1 18.9 31.1 25.1 22.0 43.0 45.2 21.6 49.4 32.2 2.1 9.6 15.1 4.6 6.8 7.5 13.4 10.8 11.8 9.3 10.4 11.0 6.5 9.3 9.6 6.6 5.5 10.0 4.5 4.4 4.8 8.3 6.4 4.8 6.4 5.7 4.4 4.6 4.0 6.3 6.1 11.0 16.0 8.6 16.6 19.4 5.9 11.6 9.1 9.6 13.7 6.1 4.6 8.3 5.7 11.6 7.3 33.3 10.0 9.7 10.3 3.9 8.3 36.0 15.0 12.1 11.8 18.0 17.7 44.8 13.4 12.9 10.8 8.6 6.1 12.7 15.2 8.9 5.5 9.5 28.6 40.9 11.8 8.2 11.6 6.6 6.4 16.1 14.0 7.2 25.3 21.6 8.0 16.5 33.2 31.2 10.9 14.6 16.1 18.0 8.8 9.5 5.1 19.7 18.9 6.6 10.6 13.1 54.7 32.5 9.0 7.0 8.5 14.2 11.0 11.1 8.1 IPO7 "Imp7, RANBP7" ENSG00000205339 "Importin 7" O95373 11 9384652-9448127 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019002, HPA056590" Approved Approved Supported Nucleoplasm,Cytosol NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA019002: AB_1856059, HPA056590: AB_2683180" "unprognostic (1.92e-1)" "prognostic unfavorable (4.98e-4)" "unprognostic (9.50e-2)" "unprognostic (1.27e-1)" "unprognostic (3.68e-1)" "unprognostic (1.60e-2)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.19e-2)" "unprognostic (7.60e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (8.38e-6)" "unprognostic (3.06e-1)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (8.08e-2)" "unprognostic (2.17e-1)" "unprognostic (3.90e-3)" 37.9 29.1 24.1 31.3 25.7 22.7 40.4 27.3 30.7 35.7 27.5 34.6 27.2 33.9 29.2 37.9 31.3 31.8 50.4 23.2 28.0 41.4 38.5 28.9 30.1 27.6 27.4 33.1 33.8 38.9 13.0 41.1 27.3 32.1 34.1 47.8 33.3 33.2 110.3 25.3 26.0 43.4 26.8 22.9 25.6 12.7 27.4 31.8 54.0 93.4 34.8 51.8 22.8 29.9 148.7 110.8 130.6 104.4 129.4 165.7 104.4 176.0 112.4 127.1 136.4 99.1 132.6 138.1 62.5 136.3 115.5 113.5 187.5 136.7 210.7 66.3 154.5 114.3 118.8 100.1 80.7 177.0 83.3 106.7 144.8 84.0 195.6 129.5 152.8 46.7 174.7 80.5 167.9 60.3 107.5 86.3 129.0 136.3 130.2 111.4 205.5 63.0 105.3 137.5 51.7 101.5 78.6 153.5 129.1 103.2 70.7 87.6 120.9 155.6 107.4 162.0 190.9 23.2 95.3 93.6 102.0 93.6 86.4 0.1 1.5 0.3 1.4 2.6 2.7 1.9 1.5 2.0 3.2 1.4 1.9 1.7 0.7 3.5 3.8 1.4 1.5 1.0 24.1 25.7 27.3 30.7 23.2 28.0 27.6 27.4 27.3 26.8 27.4 29.9 41.3 67.3 71.5 19.6 46.4 144.0 103.3 44.8 68.9 40.1 65.5 42.4 131.9 25.8 59.7 35.0 58.4 52.8 39.7 27.2 33.2 34.2 4.6 55.9 92.5 55.7 31.1 50.9 43.9 42.2 63.8 58.0 47.4 99.5 37.9 56.5 25.0 46.8 35.3 35.3 49.7 38.8 32.6 48.0 92.2 7.1 28.0 56.6 39.2 17.8 39.2 31.8 13.4 28.1 44.9 45.5 32.9 35.7 47.6 150.6 26.5 45.7 48.4 39.8 13.1 96.2 71.0 21.6 19.8 82.2 147.9 36.7 37.7 49.0 50.9 127.4 IRF2 ENSG00000168310 "Interferon regulatory factor 2" P14316 4 184387729-184474550 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 163.6;Karpas-707: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030813, CAB032306, HPA057327" Supported Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Cell Junctions, Cytosol" "CAB032306: AB_2249157, HPA030813: AB_10600718, HPA057327: AB_2683410" "prognostic favorable (6.95e-5)" "unprognostic (1.69e-3)" "unprognostic (5.43e-2)" "unprognostic (1.59e-3)" "unprognostic (2.70e-2)" "unprognostic (1.46e-1)" "unprognostic (2.48e-2)" "unprognostic (4.05e-2)" "unprognostic (8.37e-3)" "unprognostic (2.90e-2)" "unprognostic (4.00e-2)" "unprognostic (2.35e-1)" "unprognostic (6.87e-3)" "unprognostic (8.55e-3)" "unprognostic (5.25e-2)" "prognostic favorable (8.34e-5)" "unprognostic (1.31e-3)" 25.1 30.1 18.2 47.8 23.4 18.0 21.9 22.1 19.3 25.6 21.4 27.8 31.1 21.8 22.7 26.7 25.3 24.9 19.5 17.5 21.9 18.5 37.4 27.6 62.5 25.3 22.1 28.1 14.8 20.2 12.3 28.9 25.2 20.6 28.7 9.3 29.1 21.2 28.1 19.4 33.3 23.2 21.7 54.9 31.5 6.1 23.5 49.8 21.7 23.8 52.2 35.6 22.5 29.6 20.3 14.9 17.5 12.0 37.4 37.9 10.5 14.4 44.8 34.8 36.0 4.2 37.9 12.2 7.4 21.7 28.4 18.3 12.0 27.4 22.1 163.6 6.6 34.4 7.9 26.8 37.1 21.1 27.7 41.2 24.8 19.8 50.1 29.8 26.7 14.5 6.9 165.3 14.6 14.1 40.6 25.8 4.0 18.5 10.7 52.7 6.9 55.1 26.6 30.4 7.5 11.6 20.4 16.8 31.3 7.3 13.0 18.9 22.0 9.9 10.7 11.3 12.8 47.3 40.6 11.0 20.9 20.3 17.8 106.7 95.7 175.8 76.4 126.3 77.9 104.9 74.5 82.2 79.6 107.7 78.8 78.8 407.6 94.8 145.7 20.2 111.7 100.3 18.2 23.4 22.1 19.3 17.5 21.9 25.3 22.1 25.2 21.7 23.5 29.6 58.9 38.5 24.5 53.5 68.9 49.1 50.5 60.4 45.5 13.1 25.8 27.3 21.9 27.1 36.0 25.8 6.2 31.3 48.8 40.3 37.2 30.9 0.2 53.4 40.2 42.9 30.6 62.7 23.8 30.1 16.2 35.8 34.1 63.2 26.6 23.1 38.2 37.6 48.5 20.2 27.8 29.5 44.7 90.3 53.5 3.0 37.3 65.9 19.6 41.2 144.0 23.4 70.0 43.7 77.1 28.7 38.9 53.0 63.4 72.9 42.1 46.1 58.7 8.4 39.5 25.4 44.8 0.6 2.4 49.5 44.5 26.7 56.3 37.7 22.8 70.9 IRF2BPL "C14orf4, EAP1, KIAA1865" ENSG00000119669 "Interferon regulatory factor 2 binding protein like" Q9H1B7 14 77024543-77028708 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050862, HPA061333" Approved Enhanced Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA050862: AB_2681258, HPA061333: AB_2684481" "unprognostic (5.58e-2)" "unprognostic (6.48e-2)" "unprognostic (1.99e-3)" "prognostic unfavorable (5.52e-4)" "unprognostic (8.78e-3)" "unprognostic (1.57e-2)" "unprognostic (2.70e-1)" "unprognostic (1.81e-1)" "unprognostic (5.74e-2)" "unprognostic (2.53e-2)" "unprognostic (2.51e-3)" "unprognostic (5.39e-2)" "unprognostic (1.03e-3)" "unprognostic (2.55e-1)" "unprognostic (9.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" 26.1 25.3 12.2 9.2 13.9 5.6 28.5 13.4 12.0 20.1 12.8 32.4 6.9 25.8 5.1 13.3 33.7 6.5 22.6 14.1 21.1 28.7 19.1 20.9 6.2 15.2 14.8 32.4 17.5 19.8 22.6 7.9 10.9 18.4 3.3 7.3 19.2 10.1 16.8 25.2 15.1 8.0 12.6 19.0 18.8 13.5 19.0 9.7 18.7 4.2 3.3 26.4 18.2 9.4 15.4 13.2 32.2 36.3 9.6 8.8 45.8 15.9 13.0 4.4 5.9 6.2 24.8 5.4 11.3 13.6 12.4 23.6 5.6 11.8 3.7 25.8 19.1 6.9 13.0 8.5 12.5 1.9 29.7 11.8 9.1 7.8 6.8 34.8 6.0 10.9 10.4 59.4 5.7 42.2 21.0 14.5 14.5 6.6 68.2 4.4 9.1 13.0 15.6 22.4 24.9 36.0 22.5 23.2 42.5 8.6 16.1 3.4 10.4 20.2 19.5 6.8 10.3 22.9 26.3 9.0 31.3 4.7 25.8 1.7 1.4 1.3 2.8 1.9 2.7 1.4 2.5 2.6 1.3 1.6 2.0 2.3 9.0 5.9 2.3 10.7 2.6 0.8 12.2 13.9 13.4 12.0 14.1 21.1 15.2 14.8 10.9 12.6 19.0 9.4 71.4 22.4 14.3 5.9 40.2 73.7 32.5 22.5 115.5 57.1 54.6 41.5 19.5 32.9 11.6 64.4 29.2 22.8 58.9 10.8 37.2 19.6 1.3 25.3 26.0 44.0 47.6 10.8 8.2 19.0 49.7 47.8 12.2 25.6 26.6 15.2 55.6 60.5 33.3 10.1 8.6 14.7 16.2 54.7 78.9 4.0 30.1 26.6 35.6 9.4 10.0 57.8 38.1 8.5 4.8 17.8 7.0 34.3 21.1 30.0 6.7 23.1 13.8 10.4 39.5 56.4 83.2 1.6 50.5 54.2 50.6 46.0 39.0 27.5 12.8 20.6 ITSN2 "KIAA1256, PRO2015, SH3D1B, SH3P18, SWA, SWAP" ENSG00000198399 "Intersectin 2" Q9NZM3 2 24202864-24360536 "Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036475 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "Vesicles, Plasma membrane" "HPA036475: AB_10670718" "unprognostic (2.36e-1)" "unprognostic (1.28e-1)" "unprognostic (1.24e-1)" "unprognostic (5.95e-2)" "unprognostic (4.64e-1)" "prognostic favorable (2.98e-4)" "unprognostic (3.32e-2)" "unprognostic (3.83e-2)" "unprognostic (2.77e-1)" "unprognostic (1.66e-1)" "unprognostic (2.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (2.39e-1)" "unprognostic (2.72e-2)" "unprognostic (2.41e-2)" "unprognostic (2.12e-2)" 23.1 21.4 11.0 35.8 11.1 73.6 15.3 6.6 12.3 22.1 17.5 19.5 17.6 19.5 12.9 36.7 15.4 19.0 20.0 10.3 10.3 21.2 27.4 27.0 53.3 12.1 12.5 16.4 67.0 18.7 16.2 24.7 11.8 17.8 20.1 16.0 18.4 15.0 23.3 26.5 22.4 18.0 9.4 43.3 24.7 15.2 15.3 30.0 50.7 18.9 50.9 22.2 24.5 15.7 41.2 19.7 4.8 14.2 13.6 18.1 43.5 24.5 22.8 11.1 13.2 19.2 21.4 63.6 21.2 20.4 32.7 18.2 21.9 15.5 18.3 50.8 21.0 86.1 12.6 21.4 22.9 44.7 47.6 14.2 17.7 19.4 33.7 21.1 35.3 23.7 25.0 46.7 17.6 16.9 18.4 21.7 8.9 24.9 19.1 22.8 55.7 19.0 19.6 76.0 3.3 9.9 19.4 20.6 29.5 19.2 14.1 23.7 49.1 23.6 20.6 19.6 22.9 50.6 60.4 65.0 18.8 40.4 21.0 69.6 30.4 56.2 31.1 37.0 32.8 68.7 26.8 27.7 28.7 73.1 27.4 24.6 112.8 26.5 59.3 18.9 31.2 20.3 11.0 11.1 6.6 12.3 10.3 10.3 12.1 12.5 11.8 9.4 15.3 15.7 62.6 96.1 103.3 64.6 143.2 51.7 82.0 21.7 41.5 23.7 21.9 20.2 70.5 22.8 48.5 29.5 20.9 26.1 88.6 42.5 17.6 53.0 4.3 42.8 21.5 62.8 24.5 33.2 114.7 75.5 35.3 40.7 53.0 62.1 103.9 30.4 39.3 27.8 42.4 13.5 98.2 28.6 26.4 93.1 111.1 7.6 30.1 102.2 24.9 132.1 107.1 16.0 105.0 104.0 140.5 88.3 48.4 18.0 85.2 74.9 40.1 27.0 35.3 33.2 13.1 54.2 40.3 95.6 58.8 36.4 58.1 24.2 94.9 28.3 24.6 116.6 IWS1 "DKFZp761G0123, FLJ10006, FLJ14655, FLJ32319" ENSG00000163166 "Interacts with SUPT6H, CTD assembly factor 1" Q96ST2 2 127436207-127526886 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035719, HPA061866" Supported Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA035719: AB_10669527, HPA061866: AB_2684628" "unprognostic (3.11e-2)" "unprognostic (1.31e-1)" "unprognostic (1.80e-2)" "unprognostic (3.07e-2)" "unprognostic (1.44e-1)" "unprognostic (1.17e-2)" "unprognostic (8.49e-2)" "unprognostic (1.05e-1)" "unprognostic (4.27e-2)" "unprognostic (2.25e-1)" "unprognostic (4.32e-2)" "unprognostic (9.96e-2)" "unprognostic (1.42e-2)" "unprognostic (1.50e-1)" "unprognostic (9.10e-2)" "unprognostic (9.01e-2)" "unprognostic (9.81e-2)" 24.2 18.5 26.7 23.2 32.3 31.5 22.2 30.3 37.8 23.1 30.1 24.8 23.4 22.9 23.8 22.9 21.3 18.9 48.4 26.8 32.2 30.1 40.2 22.5 28.8 30.7 32.1 18.0 21.6 23.8 24.8 26.5 32.0 23.3 23.8 26.5 22.7 19.3 76.0 21.6 24.4 21.9 27.7 27.6 23.1 23.2 31.5 31.2 20.7 62.0 28.4 25.8 23.4 40.4 52.0 34.5 68.4 45.0 51.0 42.4 71.4 73.9 50.0 67.2 55.9 81.6 38.8 48.7 38.2 59.3 51.4 41.9 66.7 58.2 79.4 50.7 45.4 68.1 50.6 92.9 60.2 78.2 54.5 42.0 43.6 71.5 64.0 35.7 58.0 60.3 72.8 37.0 64.3 48.3 77.7 63.4 92.2 43.0 46.8 68.9 53.5 44.9 67.6 62.0 53.4 34.7 52.9 65.9 60.3 73.4 29.6 53.5 66.4 66.3 50.4 40.4 43.8 28.6 33.6 64.5 36.6 54.2 45.0 3.6 13.2 18.5 9.7 14.8 11.8 11.4 11.1 11.8 13.0 15.1 10.5 11.0 13.9 15.0 17.3 11.8 11.0 9.5 26.7 32.3 30.3 37.8 26.8 32.2 30.7 32.1 32.0 27.7 31.5 40.4 23.1 112.2 74.3 35.3 36.6 15.7 55.3 22.8 23.9 27.9 16.9 15.7 77.4 21.5 53.5 16.5 27.1 40.0 33.5 35.1 19.6 38.6 13.2 38.5 39.8 28.9 28.1 30.7 21.9 25.5 56.3 41.9 32.1 36.8 42.3 42.3 20.7 25.7 27.1 21.9 27.8 25.7 30.5 16.4 25.4 8.5 39.1 29.2 10.6 25.3 40.1 26.4 46.4 25.6 105.0 41.9 28.0 31.6 37.5 53.8 25.1 19.1 44.6 44.7 32.9 29.3 35.6 69.8 52.0 24.1 17.0 92.8 37.4 34.6 26.9 77.2 KCNK13 "K2p13.1, THIK-1, THIK1" ENSG00000152315 "Potassium two pore domain channel subfamily K member 13" Q9HB14 14 90061994-90185853 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.6;parathyroid gland: 6.0;testis: 9.2" "Cell type enriched" "Detected in some" 4 "Microglial cells: 41.2" "Cancer enhanced" "Detected in many" "testis cancer: 5.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.2" "Lineage enhanced" "Detected in single" "dendritic cells: 1.2" "Cell line enhanced" "Detected in some" "GAMG: 1.0;RT4: 1.9;SuSa: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA003514 Approved Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cell Junctions" "HPA003514: AB_2666978" "unprognostic (1.40e-1)" "unprognostic (1.73e-1)" "unprognostic (6.17e-2)" "unprognostic (6.31e-2)" "unprognostic (2.56e-1)" "unprognostic (5.55e-2)" "unprognostic (3.56e-2)" "unprognostic (3.98e-2)" "unprognostic (2.40e-1)" "unprognostic (2.34e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-2)" "unprognostic (1.97e-1)" "unprognostic (2.04e-2)" "unprognostic (6.32e-2)" "unprognostic (1.46e-1)" "unprognostic (5.65e-2)" 0.3 0.8 1.7 1.7 1.5 0.0 0.2 0.9 1.9 0.1 5.6 0.4 0.5 0.2 1.0 0.2 0.3 0.4 1.6 1.6 1.4 3.9 0.5 0.4 0.6 1.6 2.3 0.1 0.3 6.0 0.3 0.2 1.8 0.1 0.5 0.0 0.2 0.4 0.0 0.1 0.5 0.3 1.8 0.6 0.4 9.2 2.2 1.1 1.9 0.0 0.5 0.5 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.4 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.1 1.9 0.7 0.2 0.0 0.7 0.5 2.9 0.0 0.7 0.0 0.0 0.8 0.0 0.3 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.7 1.5 0.9 1.9 1.6 1.4 1.6 2.3 1.8 1.8 2.2 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.8 0.4 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 6.3 0.0 0.4 0.0 0.0 6.0 0.0 4.4 0.0 0.0 4.0 8.1 0.6 0.0 3.2 0.0 41.2 9.0 0.0 0.0 3.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.3 0.1 0.1 0.4 0.0 0.1 KIAA0100 "BCOX, BCOX1, CT101, DKFZp686M0843, FMP27, MGC111488" ENSG00000007202 KIAA0100 Q14667 17 28614446-28645454 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042781 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted to blood" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytosol" "HPA042781: AB_10797020" "unprognostic (1.91e-1)" "unprognostic (1.03e-2)" "unprognostic (3.47e-2)" "unprognostic (5.26e-3)" "unprognostic (2.43e-1)" "unprognostic (6.89e-2)" "prognostic unfavorable (3.47e-5)" "unprognostic (4.99e-2)" "unprognostic (3.04e-1)" "unprognostic (3.03e-3)" "unprognostic (2.40e-2)" "unprognostic (2.53e-1)" "unprognostic (4.24e-3)" "unprognostic (7.58e-2)" "unprognostic (5.84e-2)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 36.1 30.7 22.4 28.5 20.7 31.5 30.6 18.2 23.5 22.7 31.7 30.8 19.7 23.1 25.7 31.3 29.2 20.5 24.2 24.4 21.3 43.0 18.6 30.7 28.4 29.9 24.4 23.9 24.4 51.8 25.2 29.6 29.3 27.1 34.8 27.5 28.9 27.1 51.9 31.8 26.7 35.3 20.2 28.8 23.3 24.9 26.5 32.3 35.4 42.5 34.9 30.3 16.0 20.6 66.5 123.8 61.4 58.8 109.3 64.8 44.8 60.9 80.1 72.3 67.6 85.9 29.4 92.0 71.2 111.2 75.3 86.2 91.4 89.6 87.1 102.8 88.7 73.2 95.9 47.2 47.0 129.1 121.3 66.5 68.2 98.0 74.1 56.1 104.9 64.1 70.6 29.0 66.8 94.4 94.5 61.1 26.9 119.0 46.6 71.7 69.0 60.0 43.4 116.9 60.2 46.5 76.8 205.5 50.7 76.0 123.2 88.6 98.1 55.0 60.4 74.5 116.2 27.2 33.8 58.0 62.8 81.7 65.4 0.3 1.1 1.5 1.2 1.0 1.2 1.1 0.5 1.0 1.3 0.6 0.6 0.7 0.7 0.8 1.2 2.9 0.7 0.7 22.4 20.7 18.2 23.5 24.4 21.3 29.9 24.4 29.3 20.2 26.5 20.6 21.5 16.0 17.8 15.0 16.5 10.3 8.9 8.7 15.4 31.7 19.3 14.7 30.2 14.3 13.0 12.9 29.2 15.3 34.4 30.5 5.9 9.9 19.4 20.4 16.1 16.4 12.1 14.1 19.1 11.0 9.4 14.1 21.4 16.4 8.2 20.4 18.5 30.5 10.6 28.6 18.3 16.4 8.2 31.5 18.6 23.2 9.3 19.9 10.6 14.0 25.3 14.3 21.6 11.6 12.7 9.8 12.1 6.4 17.1 15.8 17.9 15.1 15.1 22.5 0.0 20.3 20.1 30.5 28.1 22.9 11.1 45.6 17.0 24.2 22.6 11.7 KIF3A "FLA10, KLP-20" ENSG00000131437 "Kinesin family member 3A" Q9Y496 5 132692628-132737638 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.3;retina: 33.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 178.7;Horizontal cells: 185.1;Inhibitory neurons: 157.0;Spermatocytes: 147.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 68.2" "Lineage enriched" "Detected in all" 10 "granulocytes: 68.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037085 Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Intermediate filaments, Cytosol" "CAB037085: AB_477147" "unprognostic (8.22e-3)" "unprognostic (2.58e-1)" "unprognostic (2.29e-3)" "unprognostic (3.59e-2)" "unprognostic (2.51e-1)" "unprognostic (3.80e-1)" "unprognostic (8.21e-4)" "unprognostic (1.30e-1)" "unprognostic (4.71e-2)" "unprognostic (1.46e-1)" "unprognostic (1.44e-2)" "unprognostic (7.64e-2)" "unprognostic (6.08e-3)" "unprognostic (8.62e-2)" "unprognostic (1.92e-1)" "unprognostic (1.17e-1)" "unprognostic (1.23e-1)" 2.6 8.0 14.3 3.8 15.2 1.6 5.0 9.7 26.3 4.4 0.0 3.4 2.5 4.7 5.0 3.3 7.0 4.0 4.6 16.5 16.7 5.8 1.4 4.5 3.9 12.6 13.1 5.1 2.7 11.8 11.3 3.2 17.6 5.1 2.6 33.9 2.8 4.8 2.5 4.0 2.0 4.5 1.3 2.8 3.7 21.5 8.2 6.0 5.4 3.1 3.7 3.8 3.0 13.8 10.6 12.6 11.4 20.8 7.7 7.8 9.4 8.9 7.0 8.2 10.9 13.0 8.0 29.7 11.6 10.4 24.8 7.2 9.6 17.6 17.2 8.6 10.2 4.3 6.9 4.7 7.9 5.3 11.4 5.8 8.6 12.1 14.0 11.4 10.4 18.8 4.8 15.3 10.1 7.9 34.5 4.2 5.5 3.8 4.8 8.8 9.2 3.2 8.4 9.4 36.2 11.9 12.0 4.3 14.4 18.6 12.8 1.6 10.9 10.1 15.9 7.3 10.6 11.5 19.6 16.4 12.9 4.4 11.1 68.2 0.6 1.9 6.3 1.5 6.9 6.7 6.5 6.1 1.3 4.0 6.4 7.0 0.6 4.8 2.0 1.2 5.4 2.0 14.3 15.2 9.7 26.3 16.5 16.7 12.6 13.1 17.6 1.3 8.2 13.8 10.9 54.5 38.0 65.3 12.0 13.6 15.6 25.5 12.5 76.5 13.7 18.7 29.9 11.5 31.7 38.6 125.1 14.6 18.4 0.8 29.4 20.5 86.2 69.7 20.4 11.3 19.8 3.4 178.7 12.9 11.5 16.8 5.6 23.7 13.9 24.6 13.2 2.4 6.2 185.1 157.0 3.8 54.9 3.5 7.7 25.0 16.4 4.8 42.7 21.5 5.4 47.0 5.2 122.6 100.7 12.4 4.6 24.5 14.4 7.6 1.1 10.8 121.0 99.6 13.1 23.8 40.5 147.1 102.6 9.0 15.9 9.9 23.6 27.7 2.1 6.0 KIF5B "KNS, KNS1" ENSG00000170759 "Kinesin family member 5B" P33176 10 32009015-32056425 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009846, HPA037589, HPA037590" Approved Enhanced "Centriolar satellite,Cytosol" NA Yes 97000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" "Centriolar satellite, Cytosol" "CAB009846: AB_2280915, HPA037589: AB_2675563, HPA037590: AB_2675564" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (4.00e-2)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.70e-1)" "unprognostic (6.37e-3)" "unprognostic (2.03e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.43e-2)" "unprognostic (2.39e-1)" "unprognostic (8.06e-2)" "unprognostic (1.76e-1)" 59.7 41.8 110.0 46.7 128.2 84.9 45.3 107.7 149.7 47.3 75.6 66.4 52.0 54.1 30.3 52.7 39.2 59.8 87.4 85.8 100.2 44.7 31.9 52.5 39.9 121.9 123.8 27.6 41.8 91.6 22.9 54.4 120.6 65.9 63.6 45.1 39.1 52.0 65.0 38.9 54.7 81.3 128.1 48.1 51.4 64.4 116.8 44.0 50.5 67.3 36.6 60.8 29.8 143.4 115.8 96.4 127.3 89.9 89.2 97.7 54.4 155.6 73.3 117.6 99.6 106.6 124.0 78.7 65.8 185.8 66.9 93.3 117.6 99.4 156.4 68.4 64.1 100.2 87.9 104.5 102.5 70.5 105.6 79.9 138.0 135.8 94.0 93.4 152.8 68.2 122.9 80.5 164.7 69.7 74.0 39.7 20.7 110.1 43.4 95.7 237.2 32.6 90.6 79.5 123.3 89.9 120.4 47.5 117.3 88.0 57.5 99.4 128.4 118.7 111.0 139.3 117.2 24.2 29.8 90.9 113.2 142.2 114.1 41.8 25.9 44.0 19.1 33.0 18.7 23.7 24.0 20.6 24.7 24.3 21.1 20.8 51.1 24.3 35.7 47.9 29.4 18.4 110.0 128.2 107.7 149.7 85.8 100.2 121.9 123.8 120.6 128.1 116.8 143.4 160.3 182.7 206.8 49.3 86.3 213.1 177.7 200.6 66.0 181.9 119.0 103.8 396.0 115.8 198.4 104.8 100.1 121.0 125.5 145.0 45.0 209.4 185.5 167.8 171.4 181.0 132.3 69.2 44.6 176.0 134.9 141.2 85.6 158.9 91.2 159.7 88.5 46.2 132.7 151.4 56.0 227.3 213.6 111.8 129.1 51.8 59.0 137.2 101.4 84.3 169.3 160.5 82.4 61.9 83.3 202.2 164.9 130.9 84.2 254.1 120.2 59.5 206.1 123.8 85.5 176.0 244.8 566.0 195.6 87.6 236.7 331.9 116.0 137.4 208.1 246.8 KIN "KIN17, Rts2" ENSG00000151657 "Kin17 DNA and RNA binding protein" O60870 10 7750962-7787993 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA replication, Host-virus interaction, mRNA processing, Stress response" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016339, HPA038700" Enhanced Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB016339: AB_627860, HPA038700: AB_2676159" "unprognostic (4.33e-3)" "unprognostic (1.24e-2)" "unprognostic (1.66e-2)" "unprognostic (1.40e-2)" "unprognostic (2.94e-2)" "unprognostic (1.31e-1)" "unprognostic (3.17e-3)" "unprognostic (1.30e-2)" "unprognostic (2.58e-1)" "unprognostic (5.59e-2)" "unprognostic (1.11e-1)" "unprognostic (5.40e-3)" "prognostic unfavorable (1.44e-7)" "unprognostic (3.98e-2)" "unprognostic (1.17e-1)" "unprognostic (4.65e-1)" "prognostic favorable (3.23e-5)" 2.1 2.4 1.9 2.6 1.9 3.1 2.6 4.4 2.5 2.8 1.8 2.2 2.4 3.3 2.8 2.0 2.4 2.1 2.1 1.8 1.8 2.3 3.3 2.2 3.4 1.7 1.8 3.0 2.7 2.0 2.6 3.0 1.9 2.5 2.2 3.4 2.5 2.1 2.8 3.4 2.4 2.1 1.4 2.8 2.5 2.1 2.0 2.4 2.9 2.2 2.7 2.1 2.4 2.6 4.3 2.7 4.1 2.5 3.3 3.9 3.3 3.8 1.7 4.5 4.8 5.2 4.2 3.3 1.9 2.3 1.4 4.0 3.5 2.3 5.1 3.8 4.0 5.2 2.7 5.1 4.6 1.9 4.1 3.3 2.5 3.4 2.2 3.7 3.4 4.1 5.3 3.1 3.5 3.9 3.8 2.9 3.9 4.5 1.6 4.8 2.9 3.1 3.8 2.3 1.7 3.8 3.0 2.9 6.2 3.8 5.5 3.8 2.5 2.9 3.2 5.1 3.1 4.0 4.7 4.1 3.6 2.9 2.0 15.9 3.9 7.1 3.7 4.3 3.7 5.9 3.3 3.1 3.0 5.4 3.6 3.8 8.8 4.9 4.1 5.8 3.0 1.5 1.9 1.9 4.4 2.5 1.8 1.8 1.7 1.8 1.9 1.4 2.0 2.6 31.5 35.3 27.2 12.1 20.7 17.3 14.6 31.3 13.6 54.8 17.2 20.1 13.0 20.0 24.8 18.4 39.6 36.7 32.0 20.4 13.7 32.9 5.7 21.7 28.4 25.6 23.3 30.3 17.4 21.5 23.8 24.0 14.3 27.9 16.4 22.9 21.0 11.9 32.1 63.9 14.8 20.3 18.3 16.9 22.8 6.2 27.7 21.8 16.0 11.2 30.7 28.7 38.1 13.0 19.4 21.2 23.6 30.9 18.1 18.9 18.2 16.9 26.0 54.7 13.1 27.8 29.7 29.1 19.0 12.1 14.3 38.4 25.7 30.1 14.7 17.3 KLHDC2 "HCLP-1, LCP" ENSG00000165516 "Kelch domain containing 2" Q9Y2U9 14 49768130-49786385 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000628 Approved Supported "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear membrane" "Nuclear bodies" "HPA000628: AB_2666051" "unprognostic (2.65e-1)" "unprognostic (8.29e-2)" "unprognostic (1.30e-2)" "unprognostic (9.01e-2)" "unprognostic (2.57e-2)" "unprognostic (5.52e-3)" "unprognostic (4.54e-2)" "unprognostic (9.72e-3)" "unprognostic (7.43e-2)" "unprognostic (1.24e-1)" "unprognostic (4.81e-3)" "unprognostic (6.77e-3)" "prognostic favorable (2.75e-10)" "unprognostic (2.20e-2)" "unprognostic (2.08e-1)" "unprognostic (1.32e-2)" "unprognostic (9.34e-2)" 21.5 22.3 12.8 8.6 13.3 10.1 19.6 13.7 16.1 18.8 15.0 23.8 18.4 20.7 14.8 15.0 17.0 13.8 38.0 14.4 14.0 34.1 49.1 14.5 10.9 12.4 12.3 25.1 30.3 16.8 17.7 12.7 13.9 18.5 18.0 23.9 20.1 20.1 53.0 18.8 21.6 14.1 13.3 12.3 24.4 23.3 12.6 15.2 28.2 38.2 10.5 22.3 16.2 14.9 14.7 12.2 22.5 11.0 31.7 27.5 23.7 15.0 28.8 18.8 19.0 7.1 19.6 29.1 20.4 27.4 10.8 12.8 13.9 13.9 15.9 20.1 14.7 9.1 8.6 17.0 23.1 19.6 7.8 28.6 23.5 8.6 16.9 23.1 17.4 24.6 11.8 21.5 15.1 17.3 20.1 8.6 16.6 17.0 34.8 15.3 24.0 18.1 8.6 31.2 27.4 22.0 25.1 46.4 17.1 17.2 17.8 7.4 14.9 17.2 13.3 13.7 7.8 29.0 19.7 17.1 9.7 10.0 9.2 12.3 9.1 19.9 11.1 6.1 13.8 18.2 16.8 17.4 9.0 19.0 23.5 15.8 8.4 16.8 5.8 6.8 18.0 12.3 12.8 13.3 13.7 16.1 14.4 14.0 12.4 12.3 13.9 13.3 12.6 14.9 40.6 41.7 52.4 30.3 42.1 48.9 53.5 64.8 53.5 65.1 48.6 40.9 9.3 77.2 53.9 47.8 50.1 102.5 40.7 68.9 107.6 59.8 96.8 44.8 41.9 36.4 57.2 47.8 30.6 85.8 68.6 51.2 67.2 38.7 30.4 62.8 45.3 91.8 33.2 65.6 35.4 75.3 63.1 28.7 33.6 27.1 81.4 26.5 39.2 18.7 36.3 73.9 54.6 28.1 33.1 54.8 78.9 77.5 74.5 53.9 143.9 170.1 27.8 98.1 65.7 46.3 90.5 238.7 93.2 42.7 66.3 82.4 44.9 54.7 78.9 55.5 KPNA4 "IPOA3, MGC12217, MGC26703, QIP1, SRP3" ENSG00000186432 "Karyopherin subunit alpha 4" O00629 3 160495007-160565571 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 124.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034336, HPA043154, HPA045500" Enhanced Enhanced Nucleoplasm NA NA 110000 "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB034336: AB_2281054, HPA043154: AB_2678343, HPA045500: AB_2679351" "unprognostic (1.58e-1)" "unprognostic (7.65e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (8.59e-4)" "unprognostic (7.56e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.24e-7)" "unprognostic (7.71e-3)" "unprognostic (1.57e-1)" "unprognostic (1.22e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (1.20e-1)" "unprognostic (1.21e-1)" "unprognostic (3.98e-2)" "unprognostic (2.21e-1)" "unprognostic (2.17e-3)" "unprognostic (1.48e-1)" 20.2 8.1 4.4 12.0 5.4 15.2 11.1 7.2 10.8 11.1 2.7 16.9 8.8 12.7 8.5 16.5 9.0 9.7 23.3 5.8 7.3 11.1 12.2 11.0 10.4 6.2 5.5 9.0 13.2 11.0 6.3 11.9 6.5 11.6 8.5 13.2 10.5 12.4 124.6 11.3 9.8 13.5 5.9 11.2 12.1 12.2 5.5 11.2 10.3 59.8 12.0 14.3 11.8 6.9 103.4 29.9 20.0 32.7 30.3 27.8 39.7 70.7 39.6 41.0 33.0 38.5 32.1 52.6 73.8 59.9 52.5 45.8 27.4 38.2 50.2 77.0 20.5 52.8 15.2 9.0 37.7 49.3 33.8 22.0 18.5 38.5 76.6 27.5 53.9 26.5 44.2 33.5 45.5 13.8 38.0 17.7 53.9 33.7 31.4 33.9 41.6 50.4 21.9 22.9 23.3 24.8 60.8 29.7 55.7 22.8 33.7 14.4 72.9 39.4 36.0 37.3 87.9 80.4 50.4 96.3 30.9 45.4 31.6 7.7 2.3 2.9 1.8 3.5 2.5 2.3 1.6 2.6 1.7 1.5 1.3 2.0 4.2 4.0 5.7 1.5 2.7 1.8 4.4 5.4 7.2 10.8 5.8 7.3 6.2 5.5 6.5 5.9 5.5 6.9 70.5 38.5 25.1 40.1 62.8 123.6 87.3 24.3 60.3 58.6 59.4 48.1 158.8 30.0 38.4 11.0 79.2 26.1 54.5 65.0 35.2 36.5 24.3 71.2 63.2 60.7 28.7 38.1 48.5 37.7 25.3 55.1 45.9 92.1 31.6 57.6 37.5 34.7 39.2 53.8 52.9 38.1 28.5 47.9 97.2 18.4 33.8 80.0 44.4 49.6 43.2 57.5 28.8 45.8 69.2 77.4 44.3 34.6 65.2 86.5 32.0 40.2 40.6 69.6 32.9 102.4 67.4 38.2 25.3 85.3 126.0 40.6 60.6 36.1 43.7 104.4 LAMTOR2 "ENDAP, MAPBPIP, MAPKSP1AP, p14, Ragulator2, ROBLD3" ENSG00000116586 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2" Q9Y2Q5 1 156054782-156058506 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 627.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004126 Approved Approved Nucleoplasm,Vesicles No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Vesicles" "HPA004126: AB_1849916" "unprognostic (2.09e-1)" "unprognostic (1.23e-1)" "unprognostic (2.07e-1)" "unprognostic (1.58e-1)" "unprognostic (8.14e-2)" "unprognostic (4.52e-2)" "unprognostic (8.64e-2)" "unprognostic (3.90e-2)" "unprognostic (3.79e-1)" "unprognostic (1.66e-2)" "unprognostic (2.06e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (1.10e-6)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (8.65e-2)" "unprognostic (1.35e-1)" 64.3 84.4 81.9 41.6 81.4 57.1 57.7 83.9 98.9 44.8 83.0 62.0 51.5 42.3 76.7 75.2 52.1 43.8 96.1 81.6 84.7 91.0 164.3 53.8 56.3 81.6 82.5 26.7 87.8 74.4 44.6 37.5 82.0 50.9 56.5 18.0 59.3 44.0 88.6 57.8 53.7 48.9 82.2 65.7 78.1 26.6 85.8 56.1 44.7 70.2 52.0 53.6 46.7 85.8 63.9 142.3 65.4 90.9 131.9 106.7 72.3 55.7 94.4 68.8 78.1 65.9 106.1 94.0 94.4 108.7 60.0 91.5 67.7 151.1 38.7 78.4 103.0 54.9 96.2 88.6 104.4 78.0 86.5 126.1 93.4 73.1 93.3 94.4 142.6 137.3 50.8 68.1 100.9 128.7 80.6 111.4 69.4 250.9 212.1 67.5 48.7 138.7 152.5 93.2 25.3 145.3 70.4 195.1 116.3 104.1 136.5 227.9 96.6 57.5 52.4 83.4 53.0 101.6 166.5 56.2 102.2 87.3 62.9 281.8 465.8 376.2 172.2 446.9 169.8 290.6 188.2 188.7 537.2 249.4 142.6 152.8 231.8 207.0 363.2 284.1 298.3 389.7 81.9 81.4 83.9 98.9 81.6 84.7 81.6 82.5 82.0 82.2 85.8 85.8 102.5 57.7 46.5 3.6 64.5 48.4 59.5 190.3 43.3 29.4 129.9 123.2 113.5 114.4 120.2 108.5 6.2 146.3 73.9 247.5 387.4 193.0 44.5 113.2 78.7 92.6 126.1 48.0 4.5 179.3 203.1 67.5 68.3 105.0 107.3 56.7 86.7 322.1 416.1 6.7 5.4 164.7 197.4 188.9 150.1 89.0 47.2 165.0 158.3 5.6 297.4 92.8 94.7 4.5 5.8 183.2 267.4 50.8 76.8 80.2 317.8 627.2 144.1 30.5 32.9 38.9 124.6 25.5 33.9 99.4 80.0 77.2 64.2 83.3 166.9 97.7 LGALS1 GBP ENSG00000100097 "Galectin 1" P09382 22 37675636-37679802 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3949.7;Langerhans cells: 4906.5;monocytes: 7118.4;Smooth muscle cells: 4703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 1649.6" "HPA000646, HPA000687, HPA001130, CAB002157" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" No Yes 10000000 20000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB002157: AB_563734, HPA000646: AB_1078935, HPA000687: AB_2756309, HPA001130: AB_2756311" "unprognostic (1.65e-1)" "unprognostic (8.13e-2)" "unprognostic (5.13e-2)" "prognostic favorable (2.36e-5)" "unprognostic (6.38e-2)" "unprognostic (2.67e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.22e-3)" "unprognostic (4.91e-3)" "unprognostic (2.51e-1)" "unprognostic (6.16e-3)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.18e-10)" "unprognostic (2.24e-2)" "unprognostic (8.13e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (5.10e-4)" 1921.2 778.5 482.4 523.8 520.7 324.7 1490.9 613.5 695.3 1805.7 465.2 1634.7 197.7 2270.1 196.8 387.4 1147.0 556.0 1397.4 457.7 549.0 362.4 277.4 920.2 176.7 694.5 576.1 1440.2 155.5 188.1 254.8 426.1 661.5 903.0 207.2 39.5 397.5 756.3 1172.9 472.8 475.3 1353.4 593.8 460.7 582.7 244.9 624.9 153.9 290.9 691.9 116.9 1059.7 1156.4 782.4 2850.9 1664.3 36.5 1440.9 3314.6 6505.1 32.7 6450.7 7619.4 4761.9 4716.9 189.6 368.3 3.3 649.1 6661.4 1609.2 296.3 58.8 4309.2 1663.3 2917.2 30.9 251.3 1606.3 791.1 2155.3 145.1 3167.7 4031.7 294.2 3785.7 1609.9 4271.1 5325.7 1.7 186.6 1163.4 3771.1 1287.6 5.2 2038.4 14.3 629.6 3914.9 5.4 2388.6 799.7 2000.0 6.4 5.5 843.4 1287.4 224.3 1644.5 66.7 1187.2 1689.0 7122.0 6224.0 3070.2 2788.9 3349.3 701.8 530.6 13.6 7291.9 762.0 2535.9 1086.5 3047.4 110.2 766.5 2320.4 113.6 567.7 694.9 754.2 3653.1 287.5 114.3 478.1 122.2 415.4 2556.7 899.2 1514.7 4667.0 482.4 520.7 613.5 695.3 457.7 549.0 694.5 576.1 661.5 593.8 624.9 782.4 1505.8 166.7 90.4 12.7 294.3 730.3 144.0 2796.6 49.5 10.0 144.2 477.9 986.3 74.4 213.4 163.7 6.2 88.0 466.5 49.9 17.6 690.2 30.9 183.0 3011.6 1063.6 3.0 74.9 7.5 90.4 1573.3 2540.4 28.1 230.3 540.0 172.2 653.2 614.1 3949.7 8.4 5.4 8.4 339.7 2159.0 4906.5 106.4 975.5 1700.0 2856.6 15.9 7118.4 278.0 588.1 4.0 17.1 233.5 6.1 1300.7 590.9 118.8 0.5 28.7 109.8 45.4 1650.1 1873.6 4703.8 33.8 13.1 18.2 588.0 151.5 767.5 197.2 11.6 57.0 LIAS LAS ENSG00000121897 "Lipoic acid synthetase" O43766 4 39459004-39485109 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 86.0;Late spermatids: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018842, HPA019076" Approved Supported Approved Nucleoplasm,Mitochondria Yes No "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Mitochondria "HPA018842: AB_1852864, HPA019076: AB_1852866" "unprognostic (3.61e-1)" "unprognostic (1.89e-1)" "unprognostic (8.44e-2)" "unprognostic (2.33e-1)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (8.31e-2)" "unprognostic (1.57e-1)" "unprognostic (4.19e-2)" "unprognostic (3.68e-2)" "unprognostic (2.46e-3)" "unprognostic (3.80e-2)" "prognostic favorable (4.11e-7)" "unprognostic (9.41e-3)" "unprognostic (2.35e-1)" "unprognostic (5.45e-2)" "unprognostic (6.98e-2)" 5.4 7.5 5.9 3.0 6.5 6.6 5.7 7.6 9.8 5.1 5.9 6.4 5.5 4.6 5.3 6.7 6.1 3.6 11.1 6.2 6.7 8.7 8.6 2.9 5.1 6.3 6.4 10.0 6.8 6.5 4.0 3.3 6.8 4.1 6.4 5.4 4.3 3.1 27.2 5.7 5.2 5.2 5.5 3.6 6.3 9.8 6.2 4.3 4.2 21.0 4.2 5.8 4.7 8.3 5.7 4.5 5.4 5.2 11.5 11.4 4.8 6.6 3.7 6.1 4.1 6.8 7.8 20.8 7.3 2.5 15.2 4.9 15.9 9.1 8.0 2.4 4.0 8.8 2.3 7.0 10.4 19.1 5.5 10.8 14.6 7.1 22.4 13.4 7.0 12.7 21.1 5.2 7.5 3.6 10.9 24.9 7.3 15.3 14.2 9.1 15.2 12.9 7.1 2.9 6.0 4.8 3.8 4.9 22.5 7.6 5.6 8.8 2.6 4.7 10.6 6.3 15.5 9.9 15.8 14.3 7.2 22.2 4.0 2.5 6.4 3.9 5.7 7.6 12.7 10.0 8.1 8.0 6.2 7.6 16.2 11.6 3.4 7.7 5.6 5.5 5.7 4.7 5.9 6.5 7.6 9.8 6.2 6.7 6.3 6.4 6.8 5.5 6.2 8.3 11.0 9.6 12.6 14.0 12.9 9.7 11.6 17.4 12.0 25.8 15.7 17.3 20.1 17.2 12.7 18.4 10.4 24.0 22.6 12.9 21.5 13.2 86.0 11.2 15.8 10.3 18.1 12.4 11.9 6.4 18.2 10.4 9.2 10.3 17.7 19.0 11.4 19.0 17.5 10.1 18.8 13.5 18.3 13.5 7.8 100.1 10.2 11.4 1.8 6.5 17.6 15.4 16.5 14.6 22.9 10.3 10.1 12.4 5.8 6.6 18.3 32.6 14.1 26.7 0.0 10.8 20.5 64.9 25.1 13.7 9.2 9.6 14.2 19.0 18.4 8.8 LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 115.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 40.0;neutrophil: 96.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 96.9" "Cell line enhanced" "Detected in all" "BEWO: 135.5;hTCEpi: 251.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB019313: , HPA008183: AB_1079252, HPA053882: AB_2682291" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (4.02e-2)" "unprognostic (5.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.96e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.57e-6)" "unprognostic (4.48e-2)" "unprognostic (1.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-1)" 20.1 14.4 25.5 39.8 27.3 53.8 30.9 25.8 22.1 26.4 32.6 34.0 21.2 17.0 7.7 71.8 34.2 21.3 14.3 20.8 27.7 27.7 33.0 46.8 23.2 37.8 34.2 21.6 28.8 27.0 21.9 48.0 32.8 36.7 34.7 25.5 50.7 19.1 18.8 71.5 29.3 15.9 32.7 37.5 30.0 19.2 33.6 21.3 42.0 9.2 17.8 25.7 45.3 33.1 26.6 4.4 17.9 10.0 7.6 8.8 135.5 17.2 8.0 16.9 14.2 22.7 12.2 25.8 29.9 26.0 8.1 52.6 20.9 90.3 10.6 19.1 22.8 18.8 21.1 24.7 11.4 35.1 33.1 14.3 251.5 13.7 41.0 114.5 43.6 20.6 10.7 18.2 23.3 20.9 21.5 12.0 16.7 68.3 6.7 28.1 30.0 14.3 19.6 62.3 22.8 20.4 13.0 82.1 35.1 54.8 68.7 13.9 26.6 15.1 23.5 8.3 16.3 10.0 16.2 22.4 9.6 16.4 6.6 5.8 5.1 40.0 3.1 3.5 5.9 2.0 5.7 4.3 1.9 2.4 5.6 4.4 96.9 6.7 1.4 4.4 15.2 4.4 25.5 27.3 25.8 22.1 20.8 27.7 37.8 34.2 32.8 32.7 33.6 33.1 19.5 32.1 17.9 16.3 5.2 35.9 37.7 24.8 59.2 9.4 18.0 23.2 25.1 10.0 32.6 5.5 20.9 69.8 15.3 39.3 3.9 13.0 1.4 49.6 19.2 22.4 13.2 10.3 6.4 45.0 52.4 7.6 48.9 41.6 23.5 8.6 14.3 7.1 18.2 3.3 11.3 42.8 18.3 8.9 8.2 1.6 4.4 13.8 3.6 16.9 5.4 16.6 2.1 2.5 15.5 25.9 21.2 4.5 6.2 27.1 12.0 10.5 36.3 22.8 19.7 7.5 17.2 15.6 18.4 46.1 39.1 115.5 9.3 7.1 51.7 29.9 LSM11 FLJ38273 ENSG00000155858 "LSM11, U7 small nuclear RNA associated" P83369 5 157743712-157760709 "Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039587 Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nuclear bodies" "HPA039587: AB_10796330" "unprognostic (3.99e-2)" "unprognostic (2.05e-1)" "unprognostic (2.38e-2)" "unprognostic (6.90e-2)" "unprognostic (2.32e-2)" "unprognostic (1.90e-1)" "unprognostic (6.61e-3)" "unprognostic (9.68e-3)" "unprognostic (1.70e-1)" "unprognostic (2.89e-2)" "unprognostic (3.77e-2)" "unprognostic (3.57e-1)" "unprognostic (1.62e-3)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (6.11e-2)" "unprognostic (3.01e-2)" 2.0 2.1 3.6 1.9 3.8 1.7 2.2 3.8 4.8 4.3 0.2 6.4 2.3 5.3 1.5 2.2 3.1 2.3 1.2 4.0 2.3 1.3 1.3 1.8 2.1 2.7 3.0 3.4 1.9 1.8 2.2 2.1 3.0 4.3 2.6 7.1 1.8 4.7 1.4 2.2 2.3 3.3 3.0 1.6 2.3 4.1 2.7 1.8 1.2 1.4 2.1 9.8 3.5 3.0 3.2 2.3 6.2 6.6 2.7 3.5 5.4 4.3 1.9 3.6 4.7 6.9 3.1 7.0 4.9 2.5 2.5 3.7 8.1 4.7 3.9 5.0 7.6 2.9 8.6 4.4 1.0 8.7 3.5 1.6 3.1 4.3 4.4 4.0 5.9 5.7 5.5 3.7 3.9 3.0 4.9 5.1 1.8 2.6 6.9 7.7 7.7 2.9 1.8 2.9 3.6 5.7 2.8 3.8 3.8 4.5 3.2 5.3 4.2 6.9 2.7 4.1 6.9 3.0 2.0 6.9 2.8 8.9 3.1 0.4 0.1 0.0 0.2 0.1 0.3 0.1 0.3 0.2 0.1 0.1 0.2 0.2 0.1 0.4 0.0 0.0 0.2 0.1 3.6 3.8 3.8 4.8 4.0 2.3 2.7 3.0 3.0 3.0 2.7 3.0 3.6 6.4 4.1 2.3 2.7 3.6 3.5 1.3 2.2 26.1 3.3 2.5 2.2 1.5 3.1 3.7 6.2 2.1 4.7 3.1 0.0 1.7 10.6 0.8 3.7 3.2 3.0 1.3 11.7 0.9 4.8 3.6 2.0 1.6 1.3 5.5 3.9 2.2 2.2 8.4 11.8 2.0 0.0 4.2 5.7 15.7 1.5 2.6 0.0 1.0 3.5 2.2 4.1 1.5 2.4 1.8 6.2 4.1 2.4 3.7 2.1 1.5 1.9 7.8 0.0 4.3 9.1 10.5 10.9 1.9 4.3 1.2 2.8 2.1 5.5 4.0 LSM6 YDR378C ENSG00000164167 "LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated" P62312 4 146175703-146200000 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, rRNA processing, tRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045079 Approved Approved "Actin filaments" NA NA 30000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Actin filaments" "HPA045079: AB_10961320" "unprognostic (5.04e-3)" "unprognostic (4.91e-2)" "unprognostic (6.81e-2)" "unprognostic (1.67e-1)" "unprognostic (6.34e-2)" "unprognostic (3.72e-2)" "unprognostic (6.57e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.88e-4)" "unprognostic (2.28e-2)" "unprognostic (4.36e-1)" "unprognostic (8.20e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (1.51e-1)" "unprognostic (2.93e-1)" "unprognostic (2.15e-1)" "unprognostic (3.08e-3)" 11.2 6.2 6.2 10.0 6.7 11.4 6.9 9.6 13.5 5.3 4.5 10.1 5.8 5.5 5.8 5.2 5.4 4.6 4.4 5.4 7.1 7.9 9.9 6.2 18.3 6.9 7.3 6.8 6.4 3.9 4.3 9.1 6.8 7.4 7.6 8.3 6.8 4.5 4.3 4.8 8.2 4.9 6.9 10.4 8.9 7.5 6.9 12.5 4.2 5.7 14.2 8.5 4.4 6.6 21.1 11.1 28.0 11.3 9.4 9.7 19.2 17.7 17.8 17.2 18.9 12.1 23.7 27.9 6.3 10.3 16.3 8.8 22.7 10.8 27.5 35.1 15.7 18.4 8.9 32.2 16.0 50.1 16.1 7.0 15.9 17.2 7.8 10.5 16.6 19.7 25.4 31.0 13.7 17.5 56.4 37.0 21.7 21.9 14.3 29.9 14.8 14.3 13.4 23.2 23.8 11.3 9.7 12.6 22.0 15.3 9.8 37.1 12.2 16.2 17.9 11.8 29.9 17.7 23.5 32.9 20.2 16.0 18.6 3.5 27.4 18.4 18.2 43.9 24.1 32.3 23.8 21.6 26.6 33.3 26.6 24.1 16.2 26.8 59.6 21.3 28.3 30.8 6.2 6.7 9.6 13.5 5.4 7.1 6.9 7.3 6.8 6.9 6.9 6.6 143.3 22.4 34.1 11.8 86.7 69.3 91.2 141.8 56.9 22.5 55.3 88.0 25.1 51.5 55.9 27.6 2.1 132.7 53.5 38.2 68.4 67.2 3.6 53.4 44.9 68.7 23.4 82.6 12.3 67.1 183.4 65.6 30.1 33.1 56.4 52.1 54.7 65.8 124.9 18.5 13.3 66.2 61.1 96.2 98.0 13.8 76.1 98.2 51.6 7.5 171.2 33.7 74.2 16.6 13.1 53.1 83.6 57.9 60.6 162.8 92.7 111.5 64.3 25.0 32.9 47.5 82.2 107.3 196.2 78.0 71.7 73.7 77.1 71.6 85.5 99.8 LTC4S MGC33147 ENSG00000213316 "Leukotriene C4 synthase" Q16873 5 179793980-179796647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid biosynthesis, Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "granulocytes: 327.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 20.2;eosinophil: 63.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 63.1" "Cell line enriched" "Detected in some" 11 "HMC-1: 102.0" "Low region specificity" "Detected in many" HPA044688 Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Endoplasmic reticulum, Cytosol" "HPA044688: " "unprognostic (8.94e-2)" "unprognostic (2.40e-2)" "unprognostic (9.35e-3)" "unprognostic (3.57e-2)" "unprognostic (1.24e-2)" "unprognostic (9.40e-2)" "unprognostic (4.53e-5)" "unprognostic (2.27e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (2.65e-1)" "unprognostic (1.98e-2)" "unprognostic (4.62e-1)" 8.9 6.9 1.1 0.5 0.8 2.3 5.5 1.5 1.3 4.2 0.7 3.3 0.7 5.7 0.0 3.1 11.8 0.3 12.4 1.0 1.4 7.1 1.9 7.7 0.2 2.1 1.5 5.7 2.0 0.2 3.5 0.4 1.4 4.8 0.2 0.0 4.3 0.8 1.0 3.1 3.2 0.4 2.9 6.1 3.0 1.5 2.6 0.0 5.9 0.0 0.1 4.8 4.0 4.7 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.9 8.9 0.2 0.4 0.3 0.6 102.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.1 6.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 3.2 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 1.0 0.1 20.2 0.5 63.1 0.8 0.6 3.0 0.3 2.1 1.5 8.6 0.2 0.4 1.0 0.3 4.7 0.0 0.4 0.2 0.6 1.1 0.8 1.5 1.3 1.0 1.4 2.1 1.5 1.4 2.9 2.6 4.7 32.3 0.0 3.2 2.9 2.3 9.9 9.6 11.2 14.8 0.4 26.4 38.6 0.0 14.3 6.2 14.7 0.0 10.4 5.0 0.6 1.9 5.9 0.3 4.0 1.5 49.5 3.0 2.1 0.8 2.4 1.9 8.3 3.1 5.6 327.4 0.5 72.1 0.9 41.5 0.0 0.7 1.7 0.0 20.8 46.3 0.9 16.4 53.9 1.8 28.1 2.0 0.1 2.1 1.0 1.5 1.9 0.5 47.4 10.0 3.7 2.2 54.8 5.8 0.5 0.0 0.8 1.6 0.1 0.7 5.2 7.0 3.0 10.0 1.5 3.1 10.0 LZTS2 "KIAA1813, LAPSER1" ENSG00000107816 "Leucine zipper tumor suppressor 2" Q9BRK4 10 100996618-101007836 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 70.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044956 Approved Approved "Plasma membrane,Cytosol" No Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA044956: AB_10795989" "unprognostic (1.42e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (8.18e-2)" "unprognostic (4.64e-2)" "unprognostic (1.56e-1)" "unprognostic (5.49e-3)" "unprognostic (3.56e-1)" "unprognostic (7.57e-2)" "unprognostic (4.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.63e-2)" "unprognostic (1.86e-1)" "unprognostic (5.46e-3)" "unprognostic (1.76e-3)" 69.9 66.0 46.8 14.9 65.5 14.4 63.3 58.0 54.1 74.3 25.8 96.3 17.5 90.3 17.7 41.0 69.2 19.8 58.9 41.2 45.8 51.8 18.0 57.1 12.1 63.7 64.3 78.6 29.5 29.1 43.6 28.5 58.5 69.5 8.9 5.9 44.3 40.6 37.8 48.9 43.0 26.6 49.0 44.4 54.9 36.2 64.1 10.8 57.6 18.0 8.1 84.1 54.4 78.9 32.9 43.1 34.6 59.7 45.0 36.3 70.8 38.7 72.8 31.9 36.0 50.5 26.6 13.1 35.1 52.5 23.0 54.6 21.5 28.2 7.8 12.8 31.9 12.1 46.4 66.3 63.6 6.4 15.2 66.1 20.2 25.1 30.1 67.3 32.8 15.6 38.7 7.3 28.7 31.6 5.8 15.8 38.8 12.6 35.2 74.7 101.3 13.5 24.4 39.3 8.4 62.8 26.3 11.9 99.9 18.6 61.0 51.6 42.1 37.9 42.6 40.5 20.7 14.0 10.2 3.3 64.0 17.7 19.4 0.0 0.7 0.4 2.7 0.4 3.7 2.3 3.4 3.0 1.1 2.9 3.5 3.0 0.3 2.9 0.1 1.8 3.0 1.5 46.8 65.5 58.0 54.1 41.2 45.8 63.7 64.3 58.5 49.0 64.1 78.9 34.7 16.0 10.5 20.2 5.3 13.4 9.0 12.4 19.4 14.4 21.7 20.3 5.2 11.5 9.4 5.5 6.2 18.6 1.9 8.0 7.9 19.1 6.8 7.9 20.5 22.9 16.7 5.0 6.8 12.6 13.2 21.8 14.8 13.0 1.3 38.9 18.5 2.6 22.2 18.5 7.7 17.8 16.2 7.2 9.2 4.1 25.7 8.4 16.0 13.1 4.8 18.9 4.1 9.0 70.3 13.3 7.9 29.3 5.4 18.1 6.5 8.3 6.1 4.0 26.3 21.1 40.7 3.8 15.0 10.8 12.1 47.1 6.0 26.9 15.1 9.7 MAGOH "MAGOH1, MAGOHA" ENSG00000162385 "Mago homolog, exon junction complex subunit" P61326 1 53226900-53238518 "Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015425, HPA043036, HPA047754" Approved Supported Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB015425: AB_629914, HPA043036: AB_2678279, HPA047754: AB_2680148" "prognostic favorable (1.85e-4)" "unprognostic (2.61e-2)" "unprognostic (5.39e-2)" "unprognostic (2.33e-1)" "unprognostic (3.59e-1)" "unprognostic (6.34e-3)" "unprognostic (3.07e-3)" "unprognostic (2.18e-1)" "unprognostic (5.17e-2)" "unprognostic (1.46e-2)" "unprognostic (8.54e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (1.45e-5)" "unprognostic (2.01e-2)" "unprognostic (1.63e-1)" "unprognostic (3.60e-2)" "unprognostic (6.75e-3)" 51.4 48.5 36.5 59.0 36.5 141.1 51.8 37.8 47.1 41.0 38.4 61.2 53.1 57.2 59.0 48.1 55.9 37.9 43.3 36.6 38.1 53.6 76.4 44.8 85.0 37.5 37.1 49.2 43.8 50.4 34.9 67.9 37.9 39.9 55.5 34.4 44.5 37.4 43.8 42.9 55.2 50.7 37.5 55.2 46.8 32.3 36.8 101.7 51.7 42.5 86.3 62.1 38.9 38.1 207.8 101.0 169.4 150.2 88.1 56.9 197.6 152.3 92.0 202.4 204.5 233.2 97.1 293.5 168.8 93.1 248.4 125.9 228.3 136.7 242.3 197.1 249.6 266.1 127.4 253.3 141.4 459.3 143.3 62.7 95.3 184.4 150.6 77.7 136.8 260.8 279.6 63.8 109.9 169.3 377.2 316.0 310.0 171.1 218.4 256.1 323.2 154.5 109.1 208.3 142.7 115.7 202.0 161.2 250.1 206.8 85.1 330.2 122.0 122.6 167.7 170.7 354.9 93.6 184.8 453.4 109.4 289.5 127.0 31.5 34.8 53.9 49.3 51.9 48.1 47.4 46.9 51.5 50.0 42.9 42.6 44.9 41.9 52.9 50.2 58.6 54.2 32.7 36.5 36.5 37.8 47.1 36.6 38.1 37.5 37.1 37.9 37.5 36.8 38.1 134.5 51.3 47.6 10.1 93.5 144.4 121.3 231.6 99.0 31.0 62.1 85.9 50.6 60.1 106.9 57.0 14.6 206.9 123.5 47.0 178.1 96.2 44.9 123.9 83.7 89.6 54.4 90.9 13.0 84.9 195.4 83.5 46.9 102.2 83.6 78.4 57.8 44.2 116.0 23.5 12.4 89.2 130.2 47.8 103.2 16.1 75.5 80.0 81.8 7.5 102.5 67.2 84.5 10.6 15.1 87.4 70.9 68.1 62.6 92.3 69.0 152.0 100.4 36.4 59.2 93.9 148.1 90.0 67.9 82.7 120.8 241.9 107.6 89.5 87.1 92.1 MAGOHB "FLJ10292, MGN2" ENSG00000111196 "Mago homolog B, exon junction complex subunit" Q96A72 12 10604193-10613609 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 119.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043036, HPA047754" Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "HPA043036: AB_2678279, HPA047754: AB_2680148" "unprognostic (1.16e-2)" "unprognostic (4.94e-2)" "unprognostic (2.71e-1)" "unprognostic (1.98e-1)" "unprognostic (1.51e-1)" "unprognostic (2.50e-2)" "unprognostic (3.42e-2)" "unprognostic (6.27e-2)" "unprognostic (8.57e-2)" "prognostic favorable (5.56e-6)" "unprognostic (1.02e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (5.04e-8)" "prognostic favorable (6.50e-4)" "unprognostic (1.61e-1)" "unprognostic (3.33e-1)" "unprognostic (6.03e-2)" 7.7 8.2 7.1 7.1 7.3 7.2 9.2 7.8 11.1 7.5 7.3 8.9 5.3 6.5 11.7 8.0 4.3 4.7 7.7 6.7 6.9 11.2 14.4 5.0 9.4 6.9 6.8 4.0 5.9 7.1 7.3 7.4 6.8 6.8 8.8 4.0 5.1 6.2 3.2 5.6 6.2 7.7 6.9 7.1 6.0 3.4 6.9 11.1 6.4 2.4 12.1 7.0 4.5 7.5 39.4 53.0 55.7 38.7 13.0 17.7 55.0 56.0 16.7 46.0 33.3 69.4 37.4 64.5 8.7 38.1 42.0 21.3 50.2 33.1 59.2 39.4 70.0 53.6 54.4 47.4 16.9 110.0 29.2 12.6 12.5 36.7 22.7 12.9 28.9 76.5 52.7 9.9 42.0 56.9 71.9 72.2 113.7 40.8 47.2 63.1 92.6 39.4 36.7 46.5 15.2 31.3 38.9 43.0 40.6 106.7 20.9 95.8 16.5 26.1 88.3 38.2 82.0 14.2 42.5 128.1 61.3 56.9 72.0 0.5 7.8 3.0 14.2 13.6 15.3 12.1 13.6 15.9 11.6 12.7 15.3 18.7 1.4 20.1 13.1 32.9 13.4 8.3 7.1 7.3 7.8 11.1 6.7 6.9 6.9 6.8 6.8 6.9 6.9 7.5 21.8 19.2 18.8 4.2 27.1 14.1 27.8 61.4 14.8 12.2 22.3 26.8 25.5 17.2 32.7 22.0 8.4 67.5 34.8 13.3 70.5 43.8 9.9 21.1 29.8 24.4 22.7 36.4 7.6 34.3 119.6 30.4 19.4 31.4 24.1 33.6 19.2 38.5 49.6 0.0 7.9 32.7 40.7 14.5 14.1 6.5 18.0 18.5 30.2 5.6 30.8 18.4 30.9 14.1 10.3 25.3 11.3 15.4 26.4 33.5 16.2 48.3 22.3 15.1 26.3 19.7 49.1 24.7 54.3 21.6 13.2 46.8 24.1 17.8 25.5 26.4 MAK16 "MAK16L, RBM13" ENSG00000198042 "MAK16 homolog" Q9BXY0 8 33485182-33501262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044417, HPA050574" Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Vesicles" "HPA044417: AB_2678935, HPA050574: AB_2681181" "unprognostic (2.10e-1)" "unprognostic (1.74e-1)" "unprognostic (8.48e-3)" "unprognostic (2.28e-2)" "unprognostic (1.72e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.00e-4)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "unprognostic (4.00e-2)" "unprognostic (3.08e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.66e-4)" "unprognostic (8.04e-2)" "unprognostic (1.20e-1)" "unprognostic (6.74e-2)" "unprognostic (1.47e-1)" 9.9 6.2 4.7 9.3 4.8 9.2 8.9 5.1 5.7 6.6 4.1 5.7 5.4 7.2 5.1 8.0 5.9 6.5 7.0 4.5 6.4 7.2 9.0 5.6 11.1 5.3 6.3 7.5 9.3 5.9 4.5 7.8 5.8 6.1 6.5 4.0 5.6 5.6 8.4 7.4 5.0 7.7 5.3 6.5 5.4 5.6 5.5 8.8 8.5 8.0 10.8 12.2 5.1 6.0 14.1 19.3 13.2 30.6 15.2 18.1 19.9 25.0 16.2 26.4 24.6 28.5 12.0 49.7 23.8 22.1 22.5 18.3 45.6 27.8 35.0 10.8 12.3 46.9 13.2 25.6 22.9 19.3 27.4 19.1 24.8 34.8 40.4 9.4 19.6 33.5 59.5 27.5 22.0 16.1 68.9 22.4 71.4 34.4 13.2 23.9 20.1 22.2 22.2 23.7 33.6 26.7 15.5 21.1 30.4 16.2 14.7 19.5 17.8 24.9 19.3 32.6 28.9 13.8 16.4 50.4 15.3 39.7 27.0 0.0 2.4 0.6 3.2 5.0 3.6 2.0 3.2 2.8 2.9 2.5 4.0 4.3 0.4 4.4 7.9 3.0 2.6 2.3 4.7 4.8 5.1 5.7 4.5 6.4 5.3 6.3 5.8 5.3 5.5 6.0 12.8 16.0 9.7 3.6 12.8 15.6 15.2 5.6 13.1 5.1 7.9 9.0 12.9 10.0 11.3 9.2 2.1 11.5 7.8 3.9 7.9 10.6 1.8 9.8 19.8 12.7 1.8 15.8 5.8 7.8 15.8 15.8 8.2 10.5 9.5 10.8 5.3 7.3 8.7 10.1 6.0 6.7 6.1 5.3 4.7 1.3 9.0 7.8 1.8 2.8 7.7 2.9 10.3 7.1 4.7 11.5 5.0 7.5 12.1 15.3 4.1 10.2 10.5 5.1 6.6 17.6 14.4 13.8 19.2 12.7 14.9 7.5 9.9 13.8 7.4 12.3 MALSU1 "C7orf30, mtRsfA" ENSG00000156928 "Mitochondrial assembly of ribosomal large subunit 1" Q96EH3 7 23298739-23311729 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "AN3-CA: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020487, HPA052210" Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA020487: AB_1845757, HPA052210: AB_2681762" "unprognostic (3.62e-1)" "unprognostic (3.68e-1)" "unprognostic (1.43e-1)" "unprognostic (4.66e-3)" "unprognostic (5.24e-3)" "prognostic unfavorable (9.71e-4)" "unprognostic (1.08e-1)" "unprognostic (1.51e-2)" "unprognostic (9.79e-2)" "unprognostic (1.83e-3)" "unprognostic (3.15e-2)" "unprognostic (7.15e-2)" "unprognostic (2.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.68e-1)" 2.6 3.2 2.8 1.6 2.9 2.0 2.2 3.3 3.7 1.9 3.7 2.7 1.0 1.8 2.3 3.9 2.3 1.4 5.1 2.7 2.7 3.1 5.6 2.0 2.9 2.5 2.5 2.6 2.9 2.3 2.0 3.4 2.5 1.6 1.7 1.8 1.9 2.3 6.3 1.8 1.8 1.8 2.4 1.8 2.2 4.9 2.9 1.5 3.3 6.4 1.9 2.1 1.9 3.0 9.2 11.4 8.8 47.8 7.8 5.4 7.6 6.1 5.0 6.2 5.7 19.7 8.1 8.8 7.0 4.4 27.5 8.7 7.9 4.3 7.6 4.2 12.9 5.2 15.0 30.4 5.0 12.2 3.2 4.6 6.5 5.3 5.8 41.5 5.8 8.5 16.5 2.3 7.9 6.4 8.4 37.2 15.1 18.0 29.0 6.5 6.7 12.4 6.1 8.1 7.0 8.5 5.0 8.9 16.1 17.2 4.5 7.3 9.8 5.2 4.0 10.0 12.5 2.6 8.6 14.7 20.6 15.0 17.3 0.7 1.0 0.7 0.8 0.8 1.0 1.0 1.2 1.0 1.0 1.0 1.4 0.9 0.7 0.9 0.7 0.9 1.2 1.0 2.8 2.9 3.3 3.7 2.7 2.7 2.5 2.5 2.5 2.4 2.9 3.0 40.5 38.5 41.7 12.7 32.1 43.7 54.8 58.3 30.1 29.1 38.6 60.8 97.1 37.1 40.0 44.1 16.7 77.6 25.7 22.3 115.4 90.6 168.5 50.2 31.9 38.9 19.2 35.3 14.7 96.3 68.7 44.9 16.3 31.7 14.5 41.5 44.3 106.8 54.0 18.5 16.6 32.5 50.8 26.3 15.1 33.6 49.4 22.3 35.6 8.4 44.5 46.8 30.9 18.6 20.2 73.2 28.2 49.2 34.9 61.2 38.1 117.6 44.6 35.8 32.9 35.6 65.6 82.2 75.2 42.4 44.2 49.8 25.2 61.7 44.4 49.2 MAPRE1 EB1 ENSG00000101367 "Microtubule associated protein RP/EB family member 1" Q15691 20 32819954-32850405 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003600, CAB009337, CAB019391" Supported Enhanced "Centriolar satellite,Cytosol" NA NA 11000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Centriolar satellite, Cytosol" "CAB009337: AB_2141629, CAB019391: , HPA003600: AB_1079309" "unprognostic (3.74e-1)" "unprognostic (1.89e-1)" "unprognostic (2.68e-1)" "unprognostic (4.48e-3)" "unprognostic (2.98e-3)" "unprognostic (1.10e-2)" "prognostic unfavorable (6.33e-4)" "unprognostic (1.25e-2)" "unprognostic (1.17e-1)" "unprognostic (7.24e-2)" "unprognostic (5.99e-2)" "unprognostic (6.05e-2)" "unprognostic (3.76e-2)" "unprognostic (3.07e-2)" "unprognostic (1.03e-1)" "unprognostic (5.42e-2)" "unprognostic (4.59e-3)" 66.7 44.5 41.2 69.7 46.7 192.7 48.3 45.3 45.5 45.9 41.9 69.0 39.7 61.0 52.9 62.7 44.8 57.4 58.2 37.0 50.0 54.1 30.4 50.6 75.8 48.0 52.5 37.8 40.4 38.3 24.3 66.8 47.9 56.0 58.0 16.1 32.7 70.6 34.1 34.7 41.2 91.3 47.7 57.7 43.9 54.4 47.5 88.0 74.1 39.7 69.3 83.1 37.8 47.0 179.7 161.4 176.6 102.0 93.5 84.3 250.7 171.3 106.3 261.0 191.0 470.0 161.9 271.2 167.4 154.8 265.6 159.9 213.1 191.6 283.7 92.4 83.1 523.3 105.0 253.2 98.7 190.6 222.8 91.6 94.1 213.8 141.7 89.3 165.0 151.4 240.0 150.6 232.4 111.0 263.0 166.2 127.6 182.7 147.5 174.4 312.8 145.9 143.0 121.8 109.7 115.3 307.2 134.3 179.4 160.6 194.3 140.0 147.5 291.9 157.7 147.3 224.7 131.5 194.5 289.6 154.9 428.3 166.0 256.8 125.8 262.1 100.1 150.8 104.0 75.1 94.1 92.9 97.4 81.8 94.6 104.3 139.7 111.1 170.6 89.5 107.1 185.6 41.2 46.7 45.3 45.5 37.0 50.0 48.0 52.5 47.9 47.7 47.5 47.0 71.6 19.2 30.2 8.1 67.0 132.8 194.4 48.1 62.0 11.1 54.7 42.3 36.5 25.8 44.5 55.2 8.4 108.0 82.0 67.6 84.1 68.8 90.2 43.5 44.7 64.8 71.5 52.8 7.8 78.3 130.0 61.4 40.8 60.9 115.4 45.7 39.3 14.9 107.0 10.1 8.5 43.6 36.7 94.6 121.2 76.6 35.8 99.5 71.2 12.2 120.5 36.5 92.7 7.5 12.6 75.0 40.5 64.3 71.1 115.3 32.6 74.3 39.4 11.5 65.7 61.5 102.8 72.1 62.1 65.2 110.8 169.2 89.8 76.6 44.4 123.1 MED1 "CRSP1, CRSP200, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2" ENSG00000125686 "Mediator complex subunit 1" Q15648 17 39404285-39451272 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 206.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017696, HPA052818" Approved Supported Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB017696: AB_1128703, HPA052818: AB_2681962" "unprognostic (1.77e-1)" "unprognostic (1.63e-1)" "unprognostic (9.26e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" "unprognostic (1.67e-1)" "unprognostic (1.21e-2)" "unprognostic (4.50e-1)" "unprognostic (7.86e-2)" "unprognostic (1.95e-3)" "unprognostic (4.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.78e-2)" "unprognostic (2.00e-1)" "unprognostic (5.94e-2)" "unprognostic (9.40e-2)" "unprognostic (5.79e-2)" 10.3 8.7 7.2 11.3 7.7 12.9 10.6 8.5 8.2 9.7 7.4 10.6 7.7 11.0 5.9 9.8 9.3 7.6 9.6 6.9 7.4 8.8 9.0 8.7 13.3 7.2 7.3 11.3 7.9 16.8 6.0 10.4 7.5 8.3 9.5 8.0 8.6 7.7 13.7 11.1 9.7 11.2 7.4 11.2 8.6 10.7 7.7 16.9 9.1 12.2 14.7 10.9 9.1 8.8 20.1 24.5 32.5 22.7 23.1 23.7 25.8 24.0 25.6 30.6 30.1 24.9 20.1 51.4 26.2 28.9 37.2 38.3 38.0 22.9 50.0 49.2 31.8 32.3 24.1 24.0 24.4 59.8 33.9 22.1 23.6 39.3 55.0 20.1 28.1 30.6 42.1 28.4 25.7 10.7 56.5 23.2 20.9 19.4 15.1 41.3 43.1 22.9 18.5 22.4 20.3 23.2 30.9 206.2 27.6 28.0 38.5 33.4 23.7 24.8 31.1 28.1 42.3 25.3 36.4 53.6 24.3 28.4 32.0 1.3 1.4 1.8 1.6 1.4 1.9 2.2 1.8 1.8 1.5 2.0 1.8 2.1 1.2 1.9 0.8 1.5 1.5 1.0 7.2 7.7 8.5 8.2 6.9 7.4 7.2 7.3 7.5 7.4 7.7 8.8 18.8 25.6 13.9 10.1 24.7 27.1 14.2 13.1 19.4 13.7 18.0 13.8 18.9 12.8 21.0 9.2 14.6 17.2 20.6 12.7 3.9 12.3 7.9 19.0 27.1 21.2 13.8 26.9 13.4 12.0 12.8 19.7 10.7 27.0 9.5 19.9 17.2 20.2 14.9 11.8 13.9 14.8 16.2 20.0 16.5 7.7 14.6 16.4 21.4 11.2 21.0 13.5 17.5 11.1 16.0 13.7 12.1 18.0 20.2 19.9 9.4 8.5 17.4 12.0 19.7 26.1 21.2 22.3 17.0 21.7 32.7 22.2 22.8 18.7 15.0 18.7 MED12 "ARC240, CAGH45, FGS1, HOPA, KIAA0192, Kto, OKS, OPA1, TNRC11, TRAP230" ENSG00000184634 "Mediator complex subunit 12" Q93074 X 71118556-71142454 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003184, HPA003185" Enhanced Approved Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA003184: AB_1079349, HPA003185: AB_1079350" "unprognostic (1.39e-1)" "unprognostic (2.23e-1)" "unprognostic (5.42e-2)" "unprognostic (2.07e-1)" "unprognostic (6.89e-3)" "unprognostic (7.14e-2)" "unprognostic (1.68e-2)" "unprognostic (1.15e-2)" "unprognostic (2.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (2.50e-1)" "unprognostic (1.22e-3)" "unprognostic (1.28e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-1)" "unprognostic (5.16e-2)" 18.9 32.3 10.1 13.4 11.6 15.1 19.3 10.8 12.2 20.3 9.3 15.2 8.1 18.1 10.7 13.4 17.8 8.5 13.4 9.7 10.5 13.1 10.3 15.2 13.6 12.3 10.9 28.9 14.9 14.1 16.3 16.8 11.3 17.4 9.2 8.2 14.3 12.6 15.4 14.7 15.9 12.6 10.2 28.4 15.5 13.4 11.2 19.1 18.1 10.6 12.2 15.2 17.1 12.0 14.2 16.4 25.5 15.3 18.3 16.1 37.1 9.9 14.0 15.2 10.8 19.8 13.1 18.5 12.7 17.2 10.5 13.8 29.7 12.3 12.1 19.6 23.0 30.7 37.9 27.5 14.3 28.8 26.2 18.9 13.2 20.0 23.3 19.6 23.8 23.1 29.0 31.6 15.2 24.3 30.5 16.3 14.7 18.2 21.3 28.0 28.5 14.0 11.8 27.5 14.0 16.9 22.7 11.8 12.2 26.2 13.9 14.2 21.1 16.5 19.7 15.4 7.0 15.4 9.5 13.7 9.8 15.8 11.2 6.9 2.1 4.3 3.0 1.9 2.5 2.0 2.1 2.8 2.1 1.9 2.3 2.0 4.1 2.7 1.3 2.8 4.4 2.4 10.1 11.6 10.8 12.2 9.7 10.5 12.3 10.9 11.3 10.2 11.2 12.0 15.4 9.6 4.2 7.2 8.4 6.0 6.3 6.5 4.6 7.2 8.6 11.0 9.3 11.5 7.6 9.2 6.2 20.7 10.9 10.8 1.9 6.9 0.4 7.9 8.9 12.8 7.8 13.7 3.8 6.3 8.0 8.2 8.6 7.1 9.5 21.1 14.6 4.4 9.1 13.5 4.2 5.8 2.0 6.5 9.8 2.3 14.0 8.9 5.4 6.5 7.4 6.3 13.4 4.0 4.2 9.4 10.0 13.5 7.3 7.5 7.5 2.7 7.5 4.9 0.0 10.0 7.6 6.6 7.3 6.1 5.7 27.2 8.8 27.9 6.8 8.6 MED19 LCMR1 ENSG00000156603 "Mediator complex subunit 19" A0JLT2 11 57703714-57712323 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039912, HPA040860" Uncertain Enhanced "Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" "HPA039912: AB_10795262, HPA040860: AB_10794153" "unprognostic (2.61e-1)" "unprognostic (1.62e-1)" "unprognostic (5.01e-2)" "unprognostic (2.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (1.34e-6)" "unprognostic (1.40e-1)" "unprognostic (4.87e-3)" "prognostic favorable (1.76e-6)" "unprognostic (3.08e-1)" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (6.71e-2)" "unprognostic (6.97e-2)" "unprognostic (4.91e-2)" "unprognostic (1.38e-2)" 11.3 18.1 22.7 6.2 23.7 6.8 11.6 20.7 41.5 11.0 21.0 10.0 9.6 11.6 13.4 15.5 9.2 6.1 11.3 23.4 22.6 14.7 13.2 8.9 7.5 21.4 22.9 9.6 11.6 9.8 16.0 10.2 22.2 12.5 7.8 12.0 12.1 8.9 10.6 15.5 9.7 8.1 22.2 10.8 11.1 22.8 26.0 8.2 13.6 9.2 9.4 10.1 11.9 23.7 30.3 19.1 22.7 21.0 23.6 21.4 27.0 25.4 19.7 23.9 24.0 13.6 23.0 16.6 38.5 24.4 21.0 22.6 17.1 16.1 21.0 21.8 18.6 14.3 11.3 12.7 35.5 15.7 16.4 17.5 28.9 23.8 46.6 16.7 31.1 13.3 15.9 16.1 29.1 14.5 22.3 29.2 19.8 21.4 37.7 21.1 32.2 20.2 15.9 12.6 17.6 24.7 20.5 20.7 47.2 19.1 43.8 16.0 25.7 20.7 24.8 49.2 22.6 19.9 20.5 15.7 28.3 11.5 22.1 27.9 25.8 31.3 29.2 37.2 31.6 45.0 32.8 31.4 25.6 39.4 34.0 32.0 16.4 24.6 39.2 36.9 33.9 26.0 22.7 23.7 20.7 41.5 23.4 22.6 21.4 22.9 22.2 22.2 26.0 23.7 40.7 9.6 27.1 4.6 32.5 87.6 60.9 72.0 62.0 38.6 37.4 39.8 14.7 30.0 40.2 51.5 35.5 58.2 32.2 36.2 39.2 44.1 12.2 33.3 37.8 39.3 23.3 21.4 9.2 45.4 48.6 38.1 20.9 34.0 22.2 39.2 36.0 26.3 29.3 37.0 8.3 38.3 54.9 17.6 31.4 15.4 28.3 18.6 37.4 2.8 26.3 37.4 24.7 5.5 7.2 40.6 33.2 29.7 22.9 53.6 32.9 47.2 42.1 59.7 19.7 31.3 50.5 111.7 97.9 42.7 82.3 73.1 35.8 37.5 31.8 52.8 MED28 "DKFZP434N185, EG1, magicin" ENSG00000118579 "Mediator complex subunit 28" Q9H204 4 17614641-17634105 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Actin-binding, Activator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035900, HPA035901" Uncertain Supported Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA035900: AB_10673223, HPA035901: AB_2674853" "unprognostic (1.14e-3)" "unprognostic (6.97e-2)" "unprognostic (1.95e-1)" "unprognostic (6.08e-3)" "unprognostic (8.22e-3)" "unprognostic (3.90e-1)" "unprognostic (1.55e-2)" "unprognostic (5.47e-2)" "unprognostic (5.71e-2)" "unprognostic (2.43e-1)" "unprognostic (2.27e-2)" "unprognostic (7.00e-2)" "unprognostic (1.16e-2)" "unprognostic (6.30e-2)" "unprognostic (8.46e-2)" "unprognostic (1.14e-1)" "unprognostic (5.07e-3)" 6.9 5.6 8.8 7.5 9.3 12.2 9.2 9.4 8.8 12.2 8.8 9.8 5.9 11.5 9.7 7.9 10.6 5.2 6.4 8.4 9.4 7.7 6.2 9.7 10.8 9.4 8.8 14.8 7.3 6.6 10.3 8.5 8.4 9.1 6.9 11.7 9.2 7.3 12.6 10.2 9.6 7.2 8.6 10.2 8.7 6.0 9.6 11.2 9.8 5.9 11.1 9.1 9.9 11.9 4.6 2.9 23.2 11.7 10.0 7.8 9.4 6.5 7.7 8.6 7.8 8.1 10.9 12.6 4.5 6.0 7.6 4.5 14.1 7.0 8.6 5.0 7.0 22.2 10.1 12.3 7.0 15.7 10.7 7.6 9.6 5.4 4.5 9.0 7.5 18.0 20.0 11.3 7.7 4.5 23.3 27.0 16.1 9.1 4.8 17.8 8.5 5.9 8.2 6.8 16.6 8.3 5.7 4.9 5.7 13.6 9.3 16.0 9.4 5.6 3.9 4.0 6.2 8.4 4.0 16.1 5.1 14.9 6.1 5.2 6.6 6.5 4.5 5.2 4.4 5.5 4.9 4.2 6.4 5.6 6.4 5.0 9.0 5.5 4.4 4.4 4.2 7.5 8.8 9.3 9.4 8.8 8.4 9.4 9.4 8.8 8.4 8.6 9.6 11.9 45.7 19.2 27.6 4.9 67.6 92.2 114.0 86.2 46.1 42.6 54.9 65.8 19.5 38.6 55.2 22.0 16.7 114.5 69.9 25.9 84.1 61.6 11.6 31.2 47.3 63.9 44.3 93.2 5.1 53.8 167.8 57.9 19.4 35.5 59.1 78.4 52.5 31.5 93.9 33.7 5.8 41.2 65.1 74.1 103.0 20.4 56.5 61.7 60.5 5.6 115.4 58.9 94.7 9.5 8.9 57.2 47.4 47.0 33.0 110.2 33.6 58.8 40.6 35.1 32.9 50.5 74.7 76.0 100.5 46.0 93.5 134.6 61.3 62.7 47.5 104.6 MED8 "ARC32, MGC17544, MGC19641" ENSG00000159479 "Mediator complex subunit 8" Q96G25 1 43383917-43389808 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028377, HPA028438" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Golgi apparatus" "HPA028377: AB_10600112, HPA028438: AB_10600057" "unprognostic (1.23e-1)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (1.49e-2)" "unprognostic (2.37e-2)" "unprognostic (8.58e-3)" "prognostic unfavorable (2.04e-7)" "unprognostic (2.60e-2)" "unprognostic (1.82e-2)" "unprognostic (1.87e-2)" "unprognostic (5.17e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.11e-7)" "unprognostic (7.08e-2)" "unprognostic (3.28e-1)" "unprognostic (3.05e-2)" "unprognostic (1.36e-1)" 30.4 27.8 24.0 20.9 25.1 27.0 26.5 24.6 29.1 24.0 27.3 25.1 23.1 21.8 24.0 43.5 20.6 16.8 20.7 24.6 25.1 27.3 43.6 24.4 21.7 26.8 25.0 21.9 29.5 20.9 36.3 25.5 26.1 23.7 24.7 40.3 26.9 20.5 22.4 36.4 22.9 24.3 24.8 25.9 28.2 22.3 25.3 17.5 25.6 14.5 28.1 24.1 27.3 27.2 56.8 35.3 31.8 38.0 48.7 48.2 42.7 56.5 51.4 65.8 69.3 65.7 40.7 33.2 39.7 71.8 43.2 34.7 50.2 47.7 62.9 47.9 48.5 56.5 60.5 82.8 82.3 50.7 57.5 47.5 60.6 71.2 84.6 39.4 53.3 31.1 50.8 57.1 42.9 36.4 26.1 40.8 30.5 52.3 39.9 30.9 37.3 53.6 43.5 35.8 33.2 25.1 33.2 53.7 111.9 43.6 36.3 97.8 39.9 29.2 52.0 55.9 80.5 67.5 83.4 40.2 60.8 61.2 39.0 44.7 57.0 54.9 33.6 53.1 32.1 44.5 30.5 38.0 57.0 36.8 30.7 32.0 45.3 32.6 48.4 26.2 43.3 38.8 24.0 25.1 24.6 29.1 24.6 25.1 26.8 25.0 26.1 24.8 25.3 27.2 25.6 16.0 12.9 5.9 25.8 18.7 23.2 35.6 11.4 27.7 23.9 23.4 12.6 27.1 28.2 14.7 14.6 52.9 26.2 26.4 33.2 51.1 13.6 16.3 23.9 25.1 19.3 42.5 11.5 75.6 72.3 30.3 23.0 19.7 31.7 21.8 16.4 27.8 60.4 16.8 8.0 29.2 28.5 18.2 32.0 22.8 24.5 26.2 19.6 4.7 35.9 32.3 28.8 6.6 13.8 57.9 30.0 21.8 41.2 24.6 40.8 48.5 16.0 58.7 26.3 12.3 42.9 64.6 45.0 24.3 25.4 88.4 23.3 31.9 22.6 39.9 MEF2A "RSRFC4, RSRFC9" ENSG00000068305 "Myocyte enhancer factor 2A" Q02078 15 99565417-99716466 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 262.8;Microglial cells: 708.3;Oligodendrocytes: 264.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004499, HPA046597" Approved Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004499: AB_627921, HPA046597: AB_2679714" "unprognostic (1.89e-1)" "unprognostic (8.82e-2)" "unprognostic (5.91e-2)" "unprognostic (8.04e-2)" "unprognostic (8.68e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-1)" "unprognostic (6.26e-2)" "unprognostic (1.93e-2)" "unprognostic (1.91e-2)" "unprognostic (7.08e-3)" "unprognostic (1.46e-1)" "prognostic favorable (6.93e-4)" "prognostic unfavorable (7.96e-4)" "unprognostic (4.69e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-3)" 32.8 22.9 18.7 20.3 25.4 18.3 22.1 16.4 27.6 27.7 12.9 23.5 12.8 34.5 23.8 21.7 21.8 22.6 89.7 21.9 12.1 24.8 24.5 30.4 25.0 17.4 20.7 30.1 12.8 37.6 9.8 26.4 15.4 23.0 15.0 24.2 19.5 23.7 61.5 54.8 17.6 35.7 18.4 27.2 17.8 15.0 28.4 23.3 19.7 81.9 22.9 22.5 16.6 25.7 17.9 10.1 16.7 8.5 20.7 26.3 8.2 17.8 40.8 14.4 19.5 10.4 24.4 22.3 24.5 38.6 22.1 19.3 17.1 14.1 18.6 15.3 24.8 45.2 22.3 9.4 35.4 18.1 21.3 17.6 23.2 19.3 39.7 59.6 26.5 18.3 16.3 41.6 27.0 7.4 29.7 26.3 8.9 11.9 14.6 43.3 36.1 18.5 29.5 24.9 10.7 14.8 27.2 11.6 51.0 17.6 11.0 16.4 43.7 39.8 21.9 19.9 21.7 22.6 27.8 48.5 27.8 19.6 38.7 7.7 12.1 14.3 3.9 15.6 3.3 15.8 3.6 3.6 13.3 12.1 5.0 3.9 10.8 6.5 19.3 7.8 2.6 5.6 18.7 25.4 16.4 27.6 21.9 12.1 17.4 20.7 15.4 18.4 28.4 25.7 152.7 80.1 43.9 113.9 87.2 88.6 31.7 26.9 62.0 52.0 31.6 37.0 175.8 20.0 40.7 29.5 50.1 7.7 32.9 26.5 25.4 18.0 10.4 80.3 60.6 100.6 12.7 24.8 262.8 18.8 3.4 61.5 34.7 130.7 31.0 30.5 50.3 41.0 39.5 30.3 174.9 17.2 12.2 107.5 63.1 7.8 55.9 104.1 35.6 708.3 65.8 25.2 23.7 157.3 264.4 26.8 22.6 64.7 55.6 27.0 18.9 19.7 51.7 44.9 72.3 62.4 69.4 29.9 29.6 29.4 50.4 9.2 27.8 28.8 17.9 26.8 METAP2 "MAP2, MNPEP, p67" ENSG00000111142 "Methionyl aminopeptidase 2" P50579 12 95473520-95515839 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013025, HPA019095" Enhanced Supported "Plasma membrane,Cytosol" NA NA 70000 "Cluster 6: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB013025: AB_2533993, HPA019095: AB_1853823" "unprognostic (1.91e-1)" "unprognostic (1.02e-1)" "unprognostic (5.92e-2)" "unprognostic (2.44e-1)" "unprognostic (3.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (4.51e-6)" "unprognostic (1.25e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-2)" "unprognostic (8.53e-2)" "unprognostic (1.66e-1)" "unprognostic (1.49e-1)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.95e-2)" "unprognostic (1.03e-1)" 52.5 58.0 41.1 51.6 44.5 102.2 55.0 45.0 53.2 46.0 39.7 50.7 36.7 54.2 52.6 54.7 42.6 47.0 65.9 40.2 49.9 55.6 84.5 49.0 78.0 46.5 43.8 60.5 52.7 52.3 36.6 51.3 48.8 43.3 50.9 30.8 40.6 101.0 119.5 58.3 37.7 54.9 42.4 40.3 37.4 61.8 44.7 69.1 51.8 78.7 125.0 62.2 41.5 50.2 192.3 157.8 163.7 129.6 98.4 156.4 125.9 186.0 127.6 177.7 125.7 228.0 88.6 542.1 113.5 133.4 101.9 120.5 187.4 142.4 203.8 131.2 161.2 244.9 113.7 165.6 104.5 313.5 117.1 137.5 148.1 164.9 164.0 210.7 192.9 184.2 321.8 60.5 135.3 125.8 230.3 213.0 204.5 109.4 233.4 179.6 141.5 178.5 123.5 198.3 127.0 165.3 166.0 132.7 169.0 140.6 159.4 146.5 165.1 100.7 98.5 115.0 195.7 87.7 246.8 585.1 58.1 173.7 129.9 77.5 70.5 32.0 60.0 52.2 74.3 114.2 66.8 67.8 66.0 101.8 79.2 74.1 3.4 72.8 65.6 85.3 71.6 46.4 41.1 44.5 45.0 53.2 40.2 49.9 46.5 43.8 48.8 42.4 44.7 50.2 87.0 282.0 238.9 22.9 101.3 233.2 130.2 141.3 97.3 70.6 119.7 95.9 143.6 100.1 133.3 290.6 66.7 146.2 87.7 96.8 164.4 115.2 189.5 114.9 260.0 110.2 91.7 278.4 35.1 145.8 161.5 112.2 53.0 153.7 122.9 140.5 112.1 314.6 98.1 75.7 49.5 119.7 73.2 141.0 89.8 123.3 100.3 83.8 92.5 20.6 103.5 72.6 81.4 26.2 41.4 130.1 105.8 106.8 87.0 108.1 93.4 186.6 92.4 83.8 98.6 137.4 133.4 378.4 207.6 95.2 215.0 172.0 80.7 101.4 144.8 110.5 MFAP1 AMP ENSG00000140259 "Microfibril associated protein 1" P55081 15 43804492-43824690 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015583, HPA042370" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Centrosome "HPA015583: , HPA042370: AB_10796904" "unprognostic (1.05e-1)" "unprognostic (5.94e-2)" "unprognostic (2.56e-2)" "unprognostic (1.23e-2)" "unprognostic (2.06e-1)" "unprognostic (5.28e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.08e-1)" "unprognostic (1.48e-1)" "unprognostic (1.66e-2)" "unprognostic (3.12e-1)" "unprognostic (7.02e-2)" "prognostic favorable (1.04e-9)" "unprognostic (1.66e-2)" "unprognostic (9.68e-2)" "unprognostic (3.82e-3)" "unprognostic (1.54e-2)" 15.9 24.0 17.5 17.6 18.0 12.9 21.4 21.3 23.2 16.6 19.7 17.1 14.5 18.8 23.4 22.2 18.4 14.9 22.1 17.7 19.3 23.7 18.1 15.2 26.6 18.3 19.3 24.8 15.3 33.2 14.5 23.2 18.7 22.8 18.1 25.0 17.0 17.7 26.3 20.5 15.0 19.1 17.7 17.1 16.8 19.3 18.5 24.4 24.7 23.2 32.4 20.6 17.5 19.1 40.1 41.0 69.4 46.0 57.9 36.3 42.7 63.1 43.8 50.3 58.2 64.1 25.6 42.8 58.7 39.4 50.9 70.8 62.5 51.7 58.9 72.9 37.6 103.7 71.6 48.5 45.4 62.3 53.2 34.1 55.3 48.0 43.3 48.0 49.8 48.3 95.8 35.7 60.9 30.0 51.1 47.0 49.2 74.2 35.4 73.9 69.6 27.6 52.0 59.0 43.8 43.0 55.6 47.0 27.0 55.2 70.7 39.5 47.4 50.6 35.8 56.3 51.7 43.5 112.2 91.8 42.5 58.4 37.9 42.5 25.5 56.9 35.3 34.8 34.7 35.0 35.1 33.6 32.6 28.3 35.7 35.0 22.6 50.5 29.1 26.8 44.1 26.3 17.5 18.0 21.3 23.2 17.7 19.3 18.3 19.3 18.7 17.7 18.5 19.1 30.4 35.3 30.2 5.2 32.8 30.3 59.6 50.1 35.9 41.8 22.4 28.8 31.0 25.8 43.2 51.5 6.2 94.6 33.2 27.4 56.7 44.2 6.2 43.1 39.9 35.6 11.3 32.0 9.0 29.4 55.0 29.8 21.4 39.4 46.3 37.6 20.7 18.8 35.4 32.0 8.6 24.4 38.7 20.7 20.5 6.3 28.0 25.5 26.6 5.6 30.6 51.5 33.0 2.0 8.2 26.8 27.1 35.7 20.6 39.3 22.1 42.9 60.0 35.2 19.7 35.9 41.7 49.7 84.8 28.1 27.7 147.4 33.6 39.4 21.3 50.6 MORC3 "KIAA0136, NXP2, ZCW5, ZCWCC3" ENSG00000159256 "MORC family CW-type zinc finger 3" Q14149 21 36320189-36386148 "Predicted intracellular proteins" "Host-virus interaction" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018406, HPA034848" Approved Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Mitochondria "HPA018406: AB_1858988, HPA034848: AB_2674359" "unprognostic (4.01e-3)" "unprognostic (4.86e-2)" "unprognostic (4.25e-2)" "unprognostic (1.38e-1)" "unprognostic (1.16e-1)" "unprognostic (6.29e-2)" "unprognostic (6.56e-2)" "unprognostic (1.40e-1)" "unprognostic (1.17e-1)" "unprognostic (2.53e-1)" "unprognostic (6.40e-2)" "unprognostic (8.61e-2)" "unprognostic (1.18e-3)" "unprognostic (1.38e-2)" "unprognostic (3.91e-1)" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" 11.2 7.5 6.3 17.3 7.9 34.5 13.9 13.6 7.7 14.6 4.7 10.9 10.9 17.3 9.4 17.7 12.0 12.6 11.6 6.4 6.6 9.4 14.1 12.9 20.3 7.2 6.2 23.8 11.1 10.4 6.5 17.2 8.0 13.6 11.6 7.7 11.5 11.8 17.7 14.9 11.0 13.9 8.6 18.6 13.0 10.8 7.2 19.4 11.7 15.8 20.0 15.4 13.8 11.8 19.7 7.8 19.1 12.8 16.5 16.3 25.1 17.9 30.0 20.3 17.5 12.8 12.9 9.4 7.0 19.9 21.0 9.8 12.9 16.9 18.8 18.7 10.3 37.2 8.2 7.2 11.4 23.4 34.7 12.0 21.3 18.3 26.5 22.2 14.5 14.6 31.0 24.3 14.9 5.8 14.1 9.8 14.2 24.9 7.9 16.4 7.5 17.8 6.6 20.1 7.1 17.4 22.2 12.3 22.8 14.3 14.9 16.3 23.3 17.7 4.9 14.3 15.2 10.9 9.8 8.9 12.7 32.3 13.2 32.5 8.9 19.5 9.1 10.9 9.0 11.3 9.9 8.6 8.8 12.6 12.6 9.1 13.5 9.9 13.6 5.7 13.4 7.9 6.3 7.9 13.6 7.7 6.4 6.6 7.2 6.2 8.0 8.6 7.2 11.8 29.0 28.9 24.1 44.4 49.6 68.3 65.7 33.1 36.5 19.4 19.6 17.4 20.4 14.3 28.9 22.0 8.4 16.1 44.3 14.7 3.9 17.8 51.7 20.9 30.1 24.1 11.4 63.3 36.4 12.5 19.7 31.0 19.4 28.0 47.5 22.4 16.8 16.5 17.5 16.8 37.1 17.1 18.3 26.8 56.8 18.3 18.6 35.8 24.9 52.5 41.4 12.2 40.2 41.7 55.3 23.3 14.5 26.7 17.1 42.0 9.5 7.1 33.5 12.2 13.1 44.8 41.5 33.5 31.4 45.8 81.7 25.2 44.6 16.7 11.1 68.1 MOSPD2 MGC26706 ENSG00000130150 "Motile sperm domain containing 2" Q8NHP6 X 14873421-14922327 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.9" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 125.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 53.4" "Group enriched" "Detected in all" 6 "granulocytes: 53.4;monocytes: 15.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003334 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA003334: AB_2146004" "unprognostic (2.74e-1)" "unprognostic (4.39e-2)" "unprognostic (6.52e-2)" "unprognostic (2.29e-1)" "unprognostic (7.57e-2)" "unprognostic (6.39e-2)" "prognostic unfavorable (8.91e-4)" "unprognostic (1.51e-1)" "unprognostic (7.24e-2)" "unprognostic (4.21e-3)" "unprognostic (1.00e-1)" "unprognostic (8.64e-2)" "unprognostic (1.04e-1)" "unprognostic (4.56e-1)" "unprognostic (1.37e-1)" "unprognostic (2.69e-1)" "unprognostic (1.96e-2)" 8.3 6.9 9.8 10.7 19.8 8.1 8.5 17.2 21.3 10.7 1.3 6.7 8.2 8.9 7.4 13.1 6.8 11.5 5.1 10.0 12.0 8.6 9.5 14.2 11.6 25.9 15.8 10.5 5.4 6.5 3.6 15.4 24.8 7.1 7.2 7.3 6.6 6.9 2.4 19.4 7.7 8.6 15.7 14.0 8.0 4.0 19.0 8.7 15.0 4.5 9.9 8.6 8.0 48.9 9.4 13.4 9.6 4.9 33.1 20.8 9.4 22.8 21.4 16.2 19.2 7.0 11.1 13.0 6.1 39.0 25.0 15.4 12.6 9.8 20.7 9.0 11.1 4.5 12.5 5.5 20.4 8.6 10.0 19.0 13.5 14.4 19.0 15.6 14.4 12.7 5.8 12.5 15.3 4.5 7.9 7.0 6.6 8.7 12.0 8.2 12.7 10.6 13.2 6.2 3.0 6.9 17.1 7.8 38.5 36.8 6.6 12.7 14.9 13.9 5.6 48.9 8.8 7.6 9.7 8.1 18.3 6.6 20.3 11.8 14.7 6.6 2.7 14.4 3.3 2.1 3.0 2.2 5.1 3.1 3.2 3.4 53.4 5.4 15.8 1.6 3.6 5.8 9.8 19.8 17.2 21.3 10.0 12.0 25.9 15.8 24.8 15.7 19.0 48.9 18.3 22.4 18.2 16.3 15.5 8.5 7.3 5.7 14.8 7.3 10.2 8.3 6.0 11.5 10.9 22.0 6.2 15.5 12.6 9.1 9.8 7.0 5.8 20.3 10.6 14.4 12.6 6.7 17.2 6.1 9.4 14.3 12.2 16.6 7.6 8.7 18.9 8.2 21.8 6.7 17.2 6.7 10.2 28.9 7.1 24.3 10.5 32.7 10.6 23.4 32.5 8.0 8.2 14.1 125.8 6.9 5.7 15.1 12.6 6.7 7.8 11.4 15.4 4.7 13.1 11.6 13.4 9.9 7.9 16.8 12.8 23.5 10.3 11.4 6.4 6.7 MPHOSPH10 "CT90, MPP10, MPP10P, PPP1R106" ENSG00000124383 "M-phase phosphoprotein 10" O00566 2 71130632-71150101 "Predicted intracellular proteins, Predicted membrane proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035059, HPA035060, HPA049907" Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA035059: AB_2674436, HPA035060: AB_10601875, HPA049907: AB_2680947" "unprognostic (3.20e-3)" "unprognostic (1.59e-1)" "unprognostic (8.51e-2)" "unprognostic (5.77e-2)" "unprognostic (1.03e-1)" "unprognostic (1.62e-1)" "unprognostic (3.58e-2)" "unprognostic (1.01e-1)" "unprognostic (6.41e-3)" "unprognostic (6.13e-2)" "unprognostic (3.50e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (3.89e-7)" "unprognostic (1.24e-1)" "unprognostic (2.91e-1)" "unprognostic (2.47e-1)" "unprognostic (2.23e-2)" 22.6 18.4 15.2 20.4 16.4 26.5 25.0 17.7 21.4 19.9 15.4 17.6 17.7 22.1 27.5 28.6 16.6 18.4 23.2 15.3 17.7 17.8 30.8 16.9 25.2 17.1 17.0 25.9 19.7 22.9 15.8 20.3 17.0 24.6 19.1 15.1 21.0 16.7 33.1 26.7 15.5 16.8 15.6 19.6 17.8 15.4 16.3 22.5 21.7 24.0 27.5 23.8 18.1 17.6 45.8 33.7 42.7 51.3 39.1 36.7 58.3 49.8 39.6 40.6 29.7 60.7 32.9 64.3 30.5 35.3 31.0 41.1 54.8 35.3 54.1 44.7 43.2 77.3 26.3 139.1 34.1 101.0 58.2 32.0 44.4 33.4 44.4 27.4 34.8 39.1 113.5 49.1 41.0 49.1 81.6 101.5 71.0 63.5 38.1 66.6 66.7 75.4 33.1 49.0 51.8 40.0 33.6 75.0 49.9 36.1 38.2 44.5 36.0 47.2 51.1 45.3 64.0 41.0 50.6 104.1 40.5 82.8 49.1 17.6 12.4 9.8 15.2 17.8 20.2 18.0 19.6 18.8 15.3 15.0 21.4 19.2 1.9 17.1 26.1 16.3 18.3 11.3 15.2 16.4 17.7 21.4 15.3 17.7 17.1 17.0 17.0 15.6 16.3 17.6 38.6 35.3 55.5 8.1 36.8 33.4 42.7 37.8 30.7 37.2 26.0 36.8 44.5 30.0 53.0 18.4 4.2 50.5 47.7 17.9 25.4 47.8 6.0 40.4 52.4 40.4 18.0 26.9 9.8 41.8 48.1 43.2 19.9 65.4 48.1 31.2 21.8 33.2 27.2 18.5 11.4 21.6 26.4 17.7 20.8 6.3 48.7 19.0 12.4 15.0 39.2 25.5 47.4 12.1 15.9 33.1 15.0 43.6 25.6 40.6 14.2 22.7 29.2 53.2 39.5 62.2 49.1 70.2 84.5 35.6 33.5 32.4 39.9 42.8 28.2 31.9 MRPL14 "MRP-L32, RPML32" ENSG00000180992 "Mitochondrial ribosomal protein L14" Q6P1L8 6 44113451-44127452 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 182.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 622.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038769, HPA076790" Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038769: AB_10673288, HPA076790: AB_2686815" "unprognostic (4.58e-1)" "unprognostic (8.39e-2)" "unprognostic (1.84e-1)" "unprognostic (7.25e-2)" "unprognostic (1.15e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-2)" "unprognostic (3.21e-2)" "unprognostic (7.20e-2)" "prognostic favorable (4.81e-4)" "unprognostic (1.74e-2)" "unprognostic (3.75e-1)" "prognostic unfavorable (7.46e-5)" "unprognostic (7.13e-2)" "unprognostic (1.65e-1)" "prognostic favorable (1.08e-4)" "unprognostic (3.27e-2)" 26.5 41.0 25.7 22.4 26.1 20.7 25.0 25.2 28.5 23.7 24.7 38.0 36.1 29.4 25.5 41.9 22.9 16.2 48.8 25.8 25.3 34.7 80.3 57.8 26.0 25.5 24.7 16.2 24.9 20.6 23.2 26.3 25.5 25.0 34.8 23.6 30.0 19.2 182.1 43.4 29.5 27.7 25.8 26.0 30.1 51.4 26.2 35.3 24.3 109.4 28.6 35.9 27.6 26.5 216.0 90.2 62.5 87.1 53.0 51.4 79.6 78.5 77.8 102.6 101.6 189.1 73.8 93.1 86.7 67.4 98.2 85.9 71.2 127.9 80.8 111.2 193.8 96.1 77.2 235.1 65.3 92.1 64.8 48.2 68.5 96.7 57.1 78.7 85.9 78.8 205.9 58.3 91.7 216.3 111.4 144.6 54.8 622.6 85.8 78.8 70.2 126.7 170.8 104.9 138.8 54.2 50.4 97.5 101.7 53.9 89.5 93.1 69.1 90.4 135.6 65.6 137.9 71.9 68.3 221.8 102.3 90.5 67.4 45.3 115.6 26.3 79.0 113.7 95.1 111.9 100.3 90.5 108.3 105.3 79.2 81.1 6.7 171.4 78.4 122.2 76.1 107.1 25.7 26.1 25.2 28.5 25.8 25.3 25.5 24.7 25.5 25.8 26.2 26.5 48.2 375.0 250.0 3.6 64.5 231.1 200.5 362.7 65.4 29.8 126.6 146.3 136.9 112.9 217.2 57.0 31.3 179.5 51.1 257.9 203.5 205.3 293.1 94.9 66.0 82.0 93.4 78.4 5.0 220.2 206.2 76.4 82.0 101.5 44.4 83.4 50.3 341.2 279.8 33.7 5.3 158.3 219.7 52.0 164.6 122.9 74.6 66.1 69.4 3.7 152.9 66.0 85.5 4.5 7.3 333.0 278.5 53.4 73.7 376.8 203.7 258.7 157.5 70.0 46.0 63.3 149.4 199.2 122.3 116.6 281.3 160.1 56.3 100.5 199.5 376.3 MRPL15 "HSPC145, L15mt, MRP-L15, MRP-L7, RPML7" ENSG00000137547 "Mitochondrial ribosomal protein L15" Q9P015 8 54135241-54148514 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 291.2;tongue: 279.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 248.4;Syncytiotrophoblasts: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044425 Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA044425: AB_10969629" "unprognostic (5.67e-3)" "unprognostic (8.89e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (9.30e-2)" "unprognostic (1.90e-2)" "unprognostic (2.57e-2)" "unprognostic (3.10e-3)" "unprognostic (1.39e-1)" "unprognostic (3.39e-2)" "unprognostic (1.94e-3)" "unprognostic (1.57e-2)" "unprognostic (2.56e-2)" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (1.06e-1)" "unprognostic (1.06e-2)" 42.5 34.4 33.2 36.4 34.1 25.1 49.3 37.0 50.5 32.6 38.7 70.8 58.6 28.6 27.7 48.8 35.6 29.0 169.6 33.5 38.3 83.8 89.2 26.5 42.9 36.6 35.7 30.5 29.2 83.4 18.6 49.6 35.8 27.5 67.5 63.1 41.4 29.0 291.2 38.5 50.6 45.4 33.8 27.3 38.4 14.7 38.3 38.1 35.2 279.4 57.4 64.1 26.3 33.0 164.1 118.9 98.0 122.6 76.1 110.5 125.8 128.4 93.0 173.3 150.2 134.1 197.1 253.9 170.3 112.1 164.4 161.5 206.2 165.5 190.4 109.9 109.5 165.8 62.4 168.5 114.5 92.0 168.9 103.3 167.4 159.5 165.6 74.7 366.7 89.4 208.2 80.8 251.3 156.1 262.4 177.3 206.2 313.9 60.8 169.5 63.6 136.3 210.8 147.1 56.5 83.7 66.8 204.0 167.0 97.4 195.2 96.6 129.6 95.8 111.7 139.5 151.5 94.6 128.4 207.1 88.8 137.8 153.4 40.1 93.8 27.3 50.7 123.4 63.8 100.6 64.8 68.4 141.1 76.6 59.0 56.9 3.3 54.0 115.7 88.9 79.8 85.8 33.2 34.1 37.0 50.5 33.5 38.3 36.6 35.7 35.8 33.8 38.3 33.0 28.0 25.6 14.4 9.4 33.1 23.6 40.7 114.5 19.4 28.2 25.0 37.2 120.9 55.8 50.4 36.8 29.2 160.3 17.6 38.7 248.4 103.2 18.7 34.0 34.4 34.8 18.0 31.7 10.9 70.9 155.2 32.8 23.9 39.2 25.4 37.9 26.4 59.2 106.1 25.2 12.4 52.5 75.3 44.5 22.9 4.3 24.8 37.9 33.8 7.5 56.5 37.4 20.6 11.1 6.0 97.5 34.3 22.6 35.3 33.9 66.8 127.0 32.1 58.8 13.1 32.1 70.1 14.8 34.3 37.3 34.4 198.9 19.7 91.3 78.3 41.8 MRPL2 "CGI-22, MRP-L14, RPML14" ENSG00000112651 "Mitochondrial ribosomal protein L2" Q5T653 6 43054029-43059438 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007455, HPA064814" Approved Supported Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA007455: AB_1079410, HPA064814: AB_2685358" "unprognostic (2.31e-1)" "unprognostic (1.49e-2)" "unprognostic (3.06e-1)" "unprognostic (1.48e-2)" "unprognostic (3.34e-1)" "unprognostic (1.62e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (3.17e-1)" "prognostic favorable (6.01e-4)" "unprognostic (3.07e-1)" "unprognostic (1.79e-1)" "unprognostic (3.24e-2)" "unprognostic (6.42e-2)" "unprognostic (2.33e-2)" "unprognostic (3.13e-1)" "unprognostic (2.78e-1)" 26.5 32.4 27.9 12.6 28.8 20.0 26.0 31.0 37.6 23.2 27.9 27.5 25.6 23.5 13.7 24.6 22.2 10.1 48.2 28.3 31.7 33.7 51.2 18.6 13.4 29.8 28.9 24.5 27.1 29.6 29.5 13.3 30.1 22.0 16.8 10.9 22.6 17.6 75.1 25.1 20.3 12.0 27.4 19.9 23.6 19.7 29.0 17.7 26.7 56.7 14.4 22.6 21.4 28.9 47.9 43.1 20.3 39.3 28.4 20.7 38.9 20.4 24.8 47.3 41.3 109.0 15.4 61.8 42.3 24.6 36.2 49.9 50.5 48.7 27.8 30.4 90.9 46.8 34.9 109.5 57.2 43.5 21.0 27.6 51.4 52.5 82.8 22.6 32.6 68.7 84.6 36.6 23.6 84.0 48.1 127.1 22.7 175.7 49.5 59.0 25.1 77.3 38.2 26.3 51.3 27.4 18.2 39.4 73.4 18.6 41.4 73.9 27.3 27.6 40.0 35.7 58.7 47.7 44.9 115.2 21.5 65.2 27.8 17.5 37.8 30.2 28.4 40.9 36.5 46.5 31.8 33.6 54.3 48.6 32.7 32.3 9.8 38.5 33.7 56.1 39.2 31.3 27.9 28.8 31.0 37.6 28.3 31.7 29.8 28.9 30.1 27.4 29.0 28.9 36.8 22.4 18.6 5.5 27.5 24.3 32.0 86.5 19.4 22.7 25.9 30.0 37.5 38.6 48.9 60.7 27.1 74.0 21.3 43.1 185.9 59.1 94.0 30.6 34.1 32.1 30.6 35.3 5.3 53.7 53.1 31.1 30.1 32.5 28.5 43.1 33.2 75.9 49.3 5.0 5.8 44.2 69.2 23.7 26.6 37.0 55.0 22.9 53.4 2.8 41.3 44.7 43.3 2.0 5.5 44.2 51.3 51.6 35.6 31.6 77.6 159.4 40.4 23.4 26.3 32.5 82.7 53.1 41.7 35.7 27.1 63.5 27.2 59.0 65.7 28.7 MRPS14 HSMRPS14 ENSG00000120333 "Mitochondrial ribosomal protein S14" O60783 1 175010789-175023425 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051087 Uncertain Supported "Nuclear membrane,Mitochondria" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" Mitochondria "Nuclear membrane" "HPA051087: AB_2681339" "unprognostic (9.24e-2)" "unprognostic (6.37e-2)" "unprognostic (1.50e-1)" "unprognostic (3.46e-1)" "unprognostic (3.44e-2)" "unprognostic (5.39e-2)" "unprognostic (1.61e-2)" "unprognostic (3.01e-2)" "unprognostic (7.32e-2)" "unprognostic (4.85e-2)" "unprognostic (7.67e-2)" "unprognostic (3.10e-2)" "unprognostic (1.31e-3)" "unprognostic (1.67e-1)" "unprognostic (8.04e-2)" "unprognostic (2.42e-1)" "unprognostic (3.21e-2)" 17.2 20.3 24.9 11.2 26.8 4.5 20.6 26.5 28.3 16.2 20.0 13.4 12.4 17.4 21.7 9.5 15.4 13.9 15.1 23.4 26.9 20.4 19.2 13.2 15.8 26.7 25.8 18.4 14.8 28.0 12.2 13.9 26.7 20.2 15.7 22.5 17.0 16.9 13.0 11.4 11.9 14.9 26.6 14.3 14.1 11.2 25.0 17.5 23.2 14.2 15.1 12.0 9.3 28.3 16.2 12.8 29.5 10.5 32.6 23.4 9.4 13.8 16.8 23.0 23.7 16.7 13.9 20.4 16.5 18.6 10.1 14.0 18.5 16.1 24.3 22.6 25.4 16.8 25.6 19.2 13.8 18.9 14.5 25.6 19.4 13.6 9.4 20.3 19.4 17.4 20.7 17.6 16.2 8.9 20.8 13.7 16.2 30.1 6.7 17.8 15.6 24.4 15.8 12.8 24.8 17.4 20.0 18.3 13.8 23.1 21.7 19.7 15.9 7.8 8.6 16.4 12.5 19.1 17.5 25.1 11.1 17.5 16.6 9.3 15.2 7.7 14.8 15.1 21.2 17.5 15.5 15.8 16.2 17.3 20.8 17.6 5.2 18.2 12.3 14.0 19.0 14.3 24.9 26.8 26.5 28.3 23.4 26.9 26.7 25.8 26.7 26.6 25.0 28.3 29.8 28.9 24.5 5.5 38.4 22.0 52.6 105.9 22.2 17.5 31.6 33.8 78.1 44.3 64.0 55.2 14.6 95.4 26.7 26.4 137.0 69.8 23.8 26.5 35.8 39.1 31.8 46.3 7.8 44.8 107.0 41.4 20.4 26.6 18.3 34.8 33.9 67.2 80.7 1.7 9.4 35.8 103.7 34.7 23.9 12.9 46.6 25.6 49.8 9.4 73.9 46.1 45.3 6.6 10.4 47.7 45.7 42.9 48.7 50.0 35.3 126.1 50.6 22.6 39.5 25.1 66.4 96.9 39.1 36.7 29.3 56.1 28.8 43.0 48.8 52.6 MSL1 "DKFZp686P24239, hMSL1, MSL-1" ENSG00000188895 "MSL complex subunit 1" Q68DK7 17 40121971-40136917 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 8.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.7" "Cell line enhanced" "Detected in all" "SK-BR-3: 358.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022800, HPA023567" Uncertain Enhanced Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA022800: AB_1853057, HPA023567: AB_1853059" "unprognostic (1.94e-1)" "unprognostic (6.28e-2)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (4.71e-2)" "unprognostic (5.39e-2)" "unprognostic (2.33e-2)" "unprognostic (1.60e-1)" "unprognostic (1.06e-2)" "unprognostic (2.24e-1)" "unprognostic (3.46e-1)" "unprognostic (7.48e-3)" "prognostic unfavorable (3.06e-6)" "unprognostic (2.92e-2)" "unprognostic (7.91e-2)" "unprognostic (5.80e-2)" "unprognostic (2.61e-2)" 60.2 52.0 34.3 48.0 33.6 56.7 56.7 26.1 39.6 76.6 16.1 62.7 51.7 75.1 55.9 48.1 77.5 38.6 46.8 32.1 26.5 57.1 43.9 61.5 50.8 24.1 25.7 58.3 59.3 47.8 78.8 48.5 22.2 59.8 46.8 41.1 56.5 51.9 63.6 60.8 61.6 53.7 21.8 88.2 57.1 66.2 27.9 62.3 79.8 51.6 51.6 53.3 62.0 27.7 35.9 42.2 88.3 57.9 78.5 67.6 45.0 61.6 65.3 76.1 68.4 42.4 37.8 78.8 45.6 65.0 48.4 65.2 74.7 40.5 78.2 68.0 59.6 43.6 60.5 50.6 40.9 59.7 81.6 56.9 63.6 56.1 46.5 77.4 71.0 47.2 69.3 62.8 61.4 22.8 95.0 64.8 37.6 39.4 27.2 77.1 48.7 72.1 55.4 38.9 80.9 48.0 57.5 358.8 46.5 80.1 83.5 81.0 58.7 51.0 56.4 37.8 52.3 98.5 58.5 77.7 52.0 43.7 60.7 0.0 1.0 0.8 1.7 0.6 0.8 1.1 0.9 1.3 0.7 0.9 0.9 0.8 8.7 0.7 0.8 1.4 0.6 0.5 34.3 33.6 26.1 39.6 32.1 26.5 24.1 25.7 22.2 21.8 27.9 27.7 44.1 28.9 40.7 42.7 22.7 50.0 37.8 21.7 69.4 55.2 41.6 32.3 29.5 25.8 25.8 11.0 12.5 15.4 43.8 36.4 3.9 17.2 16.1 35.8 53.9 43.3 31.2 22.3 39.8 20.7 15.4 37.4 20.4 48.1 3.8 24.8 36.4 35.9 25.2 52.2 33.4 29.1 8.2 36.4 42.8 28.5 58.4 34.2 32.0 33.7 30.6 31.3 30.9 25.1 32.4 24.7 32.1 39.9 26.8 72.7 35.4 9.0 32.7 28.4 39.5 29.2 40.7 71.8 49.2 57.5 65.8 17.0 29.9 27.5 31.4 58.7 MTCH2 SLC25A50 ENSG00000109919 "Mitochondrial carrier 2" Q9Y6C9 11 47617315-47642607 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 569.2;Proximal tubular cells: 508.1;Spermatocytes: 435.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038390 Approved Approved Mitochondria NA NA 14000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038390: AB_10669723" "unprognostic (4.94e-2)" "unprognostic (3.29e-1)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (4.27e-1)" "unprognostic (7.63e-3)" "unprognostic (1.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.51e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic favorable (9.05e-6)" "unprognostic (1.12e-2)" "unprognostic (8.75e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" 28.8 40.3 13.2 14.1 14.1 12.6 25.3 14.3 15.7 20.5 12.7 41.7 38.9 26.8 19.4 50.3 18.9 11.9 41.0 13.8 15.1 57.3 115.3 20.0 14.7 13.3 14.0 13.6 22.6 21.2 18.5 9.9 13.7 18.3 32.7 16.2 29.8 11.9 81.8 28.7 37.6 21.4 12.8 19.6 22.6 69.8 14.7 14.6 21.6 47.5 23.0 23.2 26.1 14.9 47.8 51.2 42.9 57.9 49.7 45.8 31.6 50.5 46.1 66.7 62.6 40.9 47.2 65.4 26.8 62.3 71.7 58.5 77.7 66.4 80.9 33.0 73.4 37.5 69.3 82.5 68.2 79.1 36.1 52.1 51.5 44.3 65.8 38.6 61.1 55.1 70.9 38.0 82.9 69.3 61.1 59.5 46.4 92.4 77.0 56.1 65.4 47.0 78.5 60.6 51.0 35.7 69.1 68.8 37.1 40.3 99.2 36.4 51.2 60.9 52.9 102.4 65.8 40.5 49.3 73.2 50.4 67.7 55.7 13.3 33.8 14.1 20.3 37.6 19.6 25.1 17.7 19.2 44.0 19.5 15.1 17.6 3.2 22.2 31.5 28.9 24.0 34.1 13.2 14.1 14.3 15.7 13.8 15.1 13.3 14.0 13.7 12.8 14.7 14.9 28.4 22.4 35.9 54.9 39.2 47.0 56.0 169.3 44.9 0.0 50.7 41.3 67.8 71.4 84.0 53.3 0.0 82.8 41.2 98.1 181.9 153.3 569.2 48.8 37.5 31.6 79.8 74.6 47.0 109.4 119.1 40.0 46.4 40.1 37.3 29.3 33.2 289.4 164.2 0.0 50.9 97.0 150.5 65.7 40.3 166.5 28.9 67.5 81.8 22.5 103.9 0.0 30.9 58.8 58.6 93.0 69.7 58.3 70.9 84.9 213.3 508.1 79.0 0.0 32.9 30.0 141.3 435.4 104.4 129.8 54.1 127.8 34.5 74.4 165.5 65.2 MTF2 "M96, PCL2, TDRD19A" ENSG00000143033 "Metal response element binding transcription factor 2" Q9Y483 1 93079235-93139079 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 117.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069047, HPA069066" Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA069047: AB_2686073, HPA069066: AB_2686078" "unprognostic (1.84e-2)" "unprognostic (1.45e-1)" "unprognostic (5.56e-2)" "unprognostic (7.88e-3)" "unprognostic (7.12e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.90e-7)" "unprognostic (1.26e-2)" "unprognostic (9.22e-3)" "unprognostic (3.98e-2)" "unprognostic (4.55e-2)" "prognostic unfavorable (1.05e-4)" "prognostic unfavorable (2.47e-7)" "unprognostic (7.19e-3)" "unprognostic (2.48e-1)" "unprognostic (2.48e-1)" "unprognostic (1.26e-2)" 5.5 6.5 5.6 10.4 6.2 23.5 9.3 10.0 7.9 7.5 5.0 7.5 7.6 8.1 7.3 5.7 6.7 6.2 4.4 5.7 5.7 7.4 6.7 7.2 20.1 4.9 5.0 10.1 5.4 5.5 5.8 12.3 5.2 5.5 7.6 8.8 5.2 4.1 7.2 7.5 7.9 5.9 5.3 11.5 6.8 16.9 5.8 29.2 7.1 5.9 18.8 6.7 6.6 6.5 20.8 9.8 33.7 22.8 5.7 5.5 38.8 12.8 10.3 21.9 27.3 17.3 11.0 66.9 23.3 8.2 19.2 10.4 31.1 13.4 32.5 25.8 22.7 45.7 15.7 22.4 8.5 61.4 19.4 7.0 7.2 21.2 12.4 10.1 21.3 50.9 53.2 20.0 13.9 9.2 88.1 49.5 57.4 8.9 13.0 70.4 40.8 17.9 20.5 22.1 20.8 24.8 21.1 25.1 26.5 34.8 15.2 42.1 12.1 14.7 21.4 14.1 19.8 15.3 19.2 117.7 2.8 35.4 9.8 9.1 7.3 11.8 7.9 8.1 9.3 7.2 8.3 10.3 9.4 8.6 9.8 8.9 5.4 10.6 5.1 8.7 10.1 4.9 5.6 6.2 10.0 7.9 5.7 5.7 4.9 5.0 5.2 5.3 5.8 6.5 36.4 28.9 29.7 52.2 53.8 46.5 28.5 37.0 26.2 0.0 33.2 25.0 13.6 18.6 32.6 38.6 0.0 68.3 64.5 26.2 7.9 33.8 5.0 24.7 29.2 40.2 32.2 51.6 70.3 19.3 67.4 23.9 23.4 36.0 60.1 56.4 43.5 15.0 34.1 0.0 58.0 31.1 40.7 27.4 54.0 7.4 32.6 34.5 17.8 54.4 50.4 0.0 90.6 68.9 68.1 30.9 28.5 23.7 39.6 41.2 39.2 15.5 21.0 0.0 39.5 24.2 39.4 125.5 89.3 24.1 43.2 60.7 54.0 45.8 33.7 48.1 MTOR "FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1" ENSG00000198793 "Mechanistic target of rapamycin kinase" P42345 1 11106535-11262551 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069425, HPA071227" Approved Approved Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "CAB069425: , HPA071227: AB_2686367" "unprognostic (3.18e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (2.45e-3)" "unprognostic (5.50e-2)" "unprognostic (2.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "unprognostic (8.24e-3)" "unprognostic (3.48e-2)" "unprognostic (1.88e-1)" "prognostic favorable (1.49e-5)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" "unprognostic (6.60e-2)" "unprognostic (7.55e-2)" 16.3 19.4 18.2 13.5 19.0 14.0 16.8 18.4 20.1 15.2 18.6 22.8 11.0 17.5 21.8 18.3 14.6 9.0 23.6 19.7 17.7 24.1 27.6 15.2 15.3 16.5 21.2 14.2 18.3 20.6 21.8 11.8 18.4 19.8 16.0 26.9 16.5 13.8 36.4 17.1 19.6 13.8 14.6 21.2 18.7 33.8 22.7 19.2 17.8 17.8 15.9 17.1 14.9 18.7 28.5 25.2 33.3 25.4 39.4 18.6 16.6 23.4 22.3 30.6 29.9 26.0 25.5 31.4 19.6 27.8 18.8 33.1 45.3 35.8 39.3 25.2 33.2 41.7 53.8 33.4 24.7 41.1 29.7 24.0 26.8 43.7 44.0 14.5 39.3 29.6 47.4 26.1 21.6 32.4 28.5 31.2 25.3 29.6 23.5 28.2 39.2 21.0 27.2 25.3 33.4 24.5 50.1 26.8 31.2 36.5 21.8 24.0 42.3 26.5 23.9 20.5 31.8 25.5 25.5 60.5 19.1 43.6 28.6 0.3 1.1 1.3 1.9 2.4 1.6 1.4 1.1 1.0 1.6 1.1 1.3 1.1 0.8 1.1 1.3 1.2 2.4 1.0 18.2 19.0 18.4 20.1 19.7 17.7 16.5 21.2 18.4 14.6 22.7 18.7 9.2 16.0 11.8 40.8 10.0 3.4 5.2 7.6 8.6 0.0 7.7 7.5 25.1 2.8 10.3 9.2 0.0 7.9 9.8 9.4 1.9 8.5 42.0 13.8 16.1 11.0 10.3 14.3 43.8 6.2 7.2 9.2 16.8 18.6 13.3 12.9 5.3 13.4 6.9 0.0 49.2 7.8 6.1 8.2 4.1 36.1 7.8 9.1 8.8 36.5 9.2 0.0 10.3 38.2 37.4 10.4 5.4 8.2 17.2 8.9 7.0 4.5 6.3 0.0 39.5 11.4 12.1 49.3 37.4 15.6 5.7 9.9 9.8 15.3 10.0 5.7 NAA15 "FLJ13340, NARG1, NATH, TBDN100" ENSG00000164134 "N-alpha-acetyltransferase 15, NatA auxiliary subunit" Q9BXJ9 4 139301505-139420033 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023589, HPA050661" Approved Supported "Nuclear bodies,Cytosol" NA NA 140000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Nuclear bodies" "HPA023589: AB_1854311, HPA050661: AB_2681208" "unprognostic (6.25e-3)" "unprognostic (5.95e-2)" "unprognostic (7.80e-3)" "unprognostic (8.45e-2)" "unprognostic (2.88e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.16e-2)" "unprognostic (9.20e-3)" "unprognostic (1.07e-2)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "unprognostic (8.65e-2)" "unprognostic (7.37e-3)" "unprognostic (2.12e-1)" "unprognostic (8.28e-3)" "unprognostic (1.58e-1)" 9.1 8.9 6.5 11.4 7.3 16.4 9.9 12.4 8.3 7.3 7.3 8.4 7.6 8.9 6.0 12.5 7.1 7.0 10.0 6.5 6.7 7.5 10.9 6.4 14.5 7.3 6.8 7.9 7.8 9.7 5.8 10.6 7.7 8.3 9.1 9.2 6.2 7.2 17.0 9.3 7.0 8.7 6.9 8.5 7.9 13.1 6.9 13.4 9.0 16.3 15.5 14.5 7.7 10.5 44.7 32.1 30.4 49.2 21.7 26.4 37.3 42.2 27.6 39.9 30.6 45.3 38.2 91.1 25.3 35.0 34.6 28.1 80.5 51.7 57.2 42.8 29.6 49.0 29.6 29.8 23.0 90.5 30.5 18.7 31.0 50.4 39.1 21.1 40.5 35.2 92.1 38.7 42.9 35.6 86.8 26.8 50.7 83.4 25.0 53.4 40.9 47.0 31.8 37.2 39.3 30.8 28.2 45.7 28.8 30.6 27.8 35.2 35.0 38.3 27.0 36.7 48.7 46.5 89.0 88.7 32.9 64.6 37.4 4.2 3.4 1.1 5.0 3.9 5.9 4.8 5.3 5.9 4.7 5.3 5.1 5.8 2.6 4.5 3.9 4.0 5.5 2.1 6.5 7.3 12.4 8.3 6.5 6.7 7.3 6.8 7.7 6.9 6.9 10.5 28.4 48.1 33.8 28.4 39.7 93.4 69.6 20.7 29.0 34.0 28.1 15.7 46.9 22.8 32.3 20.2 20.9 39.9 22.8 14.4 15.6 28.1 9.0 40.3 38.9 31.5 15.6 34.5 44.0 19.5 50.8 32.9 21.4 40.5 34.8 35.7 16.8 28.1 32.5 40.4 45.9 20.8 18.3 24.1 35.0 11.3 25.4 27.8 28.4 29.0 26.6 27.7 32.0 42.3 57.6 26.5 16.2 29.0 23.4 53.8 10.2 16.4 34.0 36.3 32.9 69.0 47.4 90.0 59.7 44.0 99.3 41.7 31.7 32.1 32.5 70.2 NAA35 "bA379P1.1, FLJ21613, FLJ22643, MAK10" ENSG00000135040 "N-alpha-acetyltransferase 35, NatC auxiliary subunit" Q5VZE5 9 85941146-86025462 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021547 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "HPA021547: AB_1853505" "unprognostic (5.87e-2)" "unprognostic (2.41e-1)" "unprognostic (4.71e-3)" "unprognostic (9.25e-3)" "unprognostic (2.37e-2)" "unprognostic (6.39e-2)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.86e-1)" "unprognostic (5.22e-3)" "unprognostic (1.56e-1)" "unprognostic (8.30e-2)" "unprognostic (1.09e-1)" "unprognostic (2.36e-3)" "unprognostic (1.88e-1)" "unprognostic (4.34e-2)" "unprognostic (9.18e-2)" "unprognostic (1.07e-2)" 7.7 12.2 6.9 6.3 7.3 6.6 9.3 9.8 7.0 8.9 8.2 11.1 8.6 9.4 7.8 10.9 8.4 5.7 8.8 6.9 7.2 8.4 8.7 7.1 6.2 6.3 6.0 9.9 10.8 9.4 12.0 7.4 6.2 9.7 10.5 14.3 10.1 6.8 17.4 9.1 8.1 7.0 6.4 6.5 8.8 15.4 8.4 7.3 10.4 13.2 7.2 9.0 9.1 8.9 25.4 15.8 17.7 13.5 9.8 13.1 24.8 15.5 15.1 16.1 13.1 12.4 15.7 8.4 8.5 15.4 13.1 34.9 15.0 18.4 16.8 22.3 13.1 21.6 19.9 14.6 16.6 30.4 17.6 13.1 15.2 17.0 24.6 12.4 14.0 15.6 25.3 15.6 14.9 14.6 15.7 16.0 17.8 28.0 18.2 14.4 26.9 12.6 17.3 20.4 16.7 15.5 17.6 15.8 13.6 17.0 11.9 11.7 14.0 11.2 12.4 16.9 15.0 22.3 29.1 5.7 16.3 12.5 10.2 1.7 2.5 5.1 3.4 2.6 4.3 9.5 3.5 3.1 3.0 9.3 4.6 3.4 1.3 3.5 1.9 2.2 3.1 2.6 6.9 7.3 9.8 7.0 6.9 7.2 6.3 6.0 6.2 6.4 8.4 8.9 14.6 3.2 14.1 58.4 16.8 16.3 20.2 19.0 19.9 25.5 18.0 13.1 23.3 18.6 22.8 11.0 22.9 22.6 14.9 20.2 1.9 19.7 8.7 29.4 18.6 14.3 20.9 14.5 51.8 25.8 18.9 13.6 16.3 22.5 12.0 32.9 9.3 9.8 12.2 21.9 58.7 14.5 30.5 11.0 8.4 5.3 9.3 10.7 14.2 52.5 12.3 18.7 14.4 44.7 68.8 18.3 16.6 11.7 17.1 22.0 12.0 8.9 33.7 36.6 13.1 21.4 24.7 56.7 36.3 17.7 16.6 31.1 15.8 24.4 16.6 19.2 NACA2 "MGC71999, NACAL" ENSG00000253506 "Nascent polypeptide associated complex subunit alpha 2" Q9H009 17 61590421-61591219 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 33 "testis: 64.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 143.4;Early spermatids: 418.0;Late spermatids: 155.3;Spermatocytes: 233.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 3.2;SK-MEL-30: 2.0" "HPA073152, HPA073648" Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA073152: AB_2686575, HPA073648: AB_2686621" "unprognostic (2.37e-1)" "unprognostic (1.50e-2)" "unprognostic (9.59e-2)" "unprognostic (5.33e-3)" "unprognostic (3.37e-1)" "unprognostic (1.45e-1)" "unprognostic (8.14e-3)" "unprognostic (4.91e-2)" "unprognostic (3.51e-2)" "unprognostic (1.18e-2)" "unprognostic (7.80e-2)" "unprognostic (2.08e-1)" "unprognostic (1.80e-2)" "unprognostic (6.88e-2)" "unprognostic (7.53e-3)" "unprognostic (5.45e-3)" "unprognostic (3.09e-3)" 1.0 0.9 0.0 0.5 0.0 0.2 1.0 0.0 0.0 1.1 0.0 0.9 0.1 0.7 0.0 1.1 0.7 0.0 0.9 0.0 0.0 1.1 0.8 0.7 0.4 0.0 0.0 1.9 1.1 0.0 0.7 0.1 0.0 1.0 0.1 0.0 0.8 0.0 1.0 1.4 0.7 0.1 0.0 0.7 0.8 64.1 0.0 0.0 0.8 0.0 0.2 0.7 1.0 0.0 0.3 0.0 0.3 0.3 0.1 0.2 0.9 0.0 0.3 0.1 0.2 0.2 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.3 0.3 0.1 0.1 0.3 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.1 1.0 0.0 0.1 0.4 3.2 0.7 0.0 0.1 0.4 0.2 1.1 0.1 0.0 0.3 0.7 0.2 0.4 2.0 0.0 0.8 1.1 0.0 0.1 0.4 0.6 0.3 0.3 0.3 0.3 0.4 0.2 0.2 0.1 0.3 0.1 0.2 0.7 0.3 0.4 0.3 0.3 0.4 0.4 0.4 0.4 0.0 0.3 0.7 0.4 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 2.0 11.2 69.3 60.6 15.0 0.0 0.7 2.2 3.2 143.4 35.8 5.2 1.8 0.0 17.5 11.7 2.9 86.1 0.3 418.0 0.5 1.1 17.6 3.6 2.7 3.4 0.8 24.1 18.5 0.0 0.6 0.0 0.7 26.4 15.1 14.5 0.0 4.0 9.1 10.2 50.7 66.3 155.3 33.8 8.2 46.2 1.0 23.7 1.5 23.7 1.5 3.5 0.6 11.1 11.3 0.0 48.1 8.1 62.1 2.9 0.9 13.1 63.8 107.3 233.8 11.4 0.0 79.3 24.1 16.3 1.1 11.8 42.9 NCL "C23, Nsr1" ENSG00000115053 Nucleolin P19338 2 231453531-231483641 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004210, HPA023981, HPA071110" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 1400000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB004210: AB_670270, HPA023981: AB_1854688, HPA071110: " "unprognostic (1.91e-1)" "unprognostic (2.53e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.63e-2)" "unprognostic (2.72e-3)" "prognostic unfavorable (1.41e-6)" "unprognostic (3.74e-2)" "unprognostic (4.31e-3)" "unprognostic (9.78e-2)" "unprognostic (6.70e-3)" "unprognostic (6.07e-2)" "unprognostic (1.66e-2)" "unprognostic (2.57e-2)" "unprognostic (9.70e-2)" "unprognostic (2.84e-2)" "unprognostic (1.42e-2)" 212.0 192.8 128.8 226.0 146.3 301.4 228.7 129.1 139.6 180.0 114.1 183.6 160.7 205.2 150.2 228.8 173.2 132.2 164.3 115.9 152.3 166.2 218.5 147.4 289.7 148.8 141.5 258.2 209.0 258.9 115.9 203.4 140.4 155.4 219.2 147.1 157.0 160.9 350.9 197.1 157.4 201.0 137.9 176.3 164.7 126.2 142.1 347.0 198.4 228.2 329.0 271.1 169.1 143.9 718.3 691.8 715.7 640.1 485.7 592.0 823.0 790.4 497.2 690.8 628.2 1227.4 521.4 1083.7 608.6 651.0 892.6 719.5 1614.4 1059.9 1284.7 554.6 644.0 1587.3 605.9 1749.5 544.0 1930.4 632.7 513.5 613.2 872.3 1019.6 394.9 834.2 770.5 1745.4 378.6 760.5 1176.4 1443.2 1086.7 1202.0 728.7 435.9 1290.8 1452.0 918.4 583.8 959.9 749.0 502.0 555.8 704.5 706.9 625.7 476.8 985.3 686.3 611.4 626.7 714.5 1063.7 624.3 554.5 1885.9 467.2 1173.1 685.2 27.3 95.6 62.5 136.5 100.3 152.8 113.5 118.4 121.9 130.6 111.9 130.3 114.2 16.8 177.8 121.7 102.0 102.3 151.0 128.8 146.3 129.1 139.6 115.9 152.3 148.8 141.5 140.4 137.9 142.1 143.9 286.2 291.7 411.7 8.1 468.9 459.9 633.8 241.0 644.9 145.0 315.2 303.8 320.9 147.3 401.6 195.0 47.9 386.9 596.2 215.0 230.9 294.4 20.6 348.7 669.8 291.1 200.0 419.2 9.3 254.4 444.6 370.9 292.0 421.8 451.7 262.7 130.6 242.0 239.5 80.8 10.4 319.6 156.6 133.7 231.1 32.2 217.2 281.8 165.4 10.3 268.9 199.6 346.1 14.1 14.9 268.0 153.9 159.9 543.5 651.1 120.1 277.6 250.3 141.0 151.2 548.9 442.0 433.3 532.4 707.9 441.4 379.0 454.0 442.6 380.6 449.1 NCOA6 "AIB3, ASC2, KIAA0181, NRC, PRIP, RAP250, TRBP" ENSG00000198646 "Nuclear receptor coactivator 6" Q14686 20 34689097-34825651 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 130.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004198, HPA050211" Supported Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA004198: AB_1078228, HPA050211: AB_2681052" "unprognostic (2.48e-1)" "unprognostic (4.81e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.65e-4)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.87e-2)" "unprognostic (1.51e-1)" "prognostic favorable (8.78e-5)" "unprognostic (9.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (4.42e-2)" 10.2 9.0 5.2 9.1 6.7 14.0 9.2 12.7 12.4 10.8 4.8 12.9 13.2 10.7 12.2 11.7 11.3 8.8 9.2 6.1 8.2 9.9 8.4 10.4 8.9 6.3 4.6 11.6 12.6 22.0 10.0 13.5 4.6 9.8 14.5 26.7 12.9 11.3 12.7 13.5 12.0 13.2 2.3 9.4 11.4 18.8 7.4 18.1 13.8 13.1 10.3 10.4 10.5 9.6 25.2 14.7 32.6 19.7 17.5 19.4 21.3 12.0 15.3 21.1 16.9 37.9 17.2 17.7 12.9 21.5 25.8 30.0 29.3 20.2 23.9 9.0 13.2 41.6 16.7 22.4 19.3 23.5 29.4 14.8 36.5 19.8 24.5 14.6 20.2 20.1 21.5 23.7 17.7 16.3 37.5 14.8 6.7 21.0 21.1 24.9 39.3 15.9 15.6 16.6 27.2 18.5 22.0 52.5 20.5 15.0 22.2 18.5 20.0 34.1 20.7 25.6 20.2 26.9 24.3 20.0 22.5 13.5 15.5 1.1 0.6 2.5 0.9 0.5 0.8 1.0 0.8 0.8 1.1 0.8 0.7 0.5 1.5 0.7 0.7 1.0 0.5 0.5 5.2 6.7 12.7 12.4 6.1 8.2 6.3 4.6 4.6 2.3 7.4 9.6 17.3 25.6 16.0 54.9 11.0 17.0 9.1 10.6 13.6 28.8 14.3 10.9 20.1 18.6 11.6 16.5 29.2 13.0 12.2 31.9 5.9 12.5 23.5 16.4 21.3 14.0 10.8 13.3 50.9 12.4 12.1 14.5 15.8 23.3 6.3 18.5 13.9 12.1 10.8 33.7 58.8 17.4 20.3 12.2 10.3 17.3 18.0 13.0 10.6 45.9 17.6 11.5 13.4 54.3 130.4 15.4 12.4 13.5 14.2 16.9 20.3 9.3 17.5 29.8 26.3 16.6 16.9 25.6 27.1 19.2 20.9 15.9 13.1 13.6 17.6 14.6 NDUFAF6 "C8orf38, MGC40214" ENSG00000156170 "NADH:ubiquinone oxidoreductase complex assembly factor 6" Q330K2 8 94895767-95116455 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047148, HPA050545" Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA047148: AB_2679954, HPA050545: AB_2681166" "unprognostic (1.97e-3)" "unprognostic (1.62e-3)" "unprognostic (2.46e-1)" "unprognostic (1.29e-3)" "unprognostic (8.73e-2)" "unprognostic (3.45e-2)" "unprognostic (7.62e-3)" "unprognostic (2.52e-2)" "unprognostic (9.61e-2)" "unprognostic (3.85e-1)" "unprognostic (3.09e-2)" "unprognostic (4.35e-2)" "unprognostic (4.04e-3)" "unprognostic (9.44e-2)" "unprognostic (1.57e-2)" "unprognostic (1.45e-2)" "unprognostic (2.32e-3)" 4.7 3.1 6.9 4.1 7.7 5.5 5.3 8.8 8.1 1.9 5.1 4.4 2.1 3.2 5.7 4.3 4.2 1.9 8.8 6.4 7.8 4.4 10.9 2.6 4.9 6.9 7.6 3.9 3.1 3.5 2.6 3.6 7.3 3.5 5.5 7.4 2.2 3.4 14.6 5.6 3.0 3.2 6.7 3.1 4.3 4.0 7.6 4.7 6.3 13.8 5.2 2.5 1.7 8.9 7.7 4.5 5.4 5.1 3.5 4.3 11.1 8.0 5.0 6.6 4.8 3.6 3.7 14.8 5.3 3.7 2.0 6.3 7.8 5.4 4.9 3.7 15.1 13.7 10.0 6.7 5.4 5.1 6.9 6.5 9.0 3.8 6.1 3.0 3.8 12.1 9.9 8.0 8.0 6.8 13.0 16.5 5.9 10.0 10.6 8.6 4.3 11.3 6.1 7.3 10.1 5.5 4.1 2.5 10.8 6.5 10.1 4.2 4.8 4.7 3.7 3.7 5.8 10.7 8.5 12.4 3.9 13.5 2.7 1.9 1.8 3.0 2.3 1.1 2.9 5.8 3.2 2.2 2.4 5.4 3.1 2.3 0.9 2.9 2.2 2.1 2.9 1.9 6.9 7.7 8.8 8.1 6.4 7.8 6.9 7.6 7.3 6.7 7.6 8.9 23.4 12.8 15.9 35.3 23.6 9.7 10.1 21.5 19.4 22.7 25.7 27.4 32.0 28.6 21.2 12.9 16.7 24.0 14.3 18.5 43.0 15.8 28.5 13.5 9.1 14.8 12.5 23.3 31.8 34.7 30.2 9.4 10.7 9.8 31.8 21.5 12.1 28.3 22.6 25.2 37.0 15.3 24.4 7.3 5.6 8.1 10.5 10.1 14.2 33.7 12.0 25.6 6.2 43.2 58.3 19.3 18.2 13.9 53.1 11.2 23.2 38.2 24.7 23.6 13.1 11.9 21.4 28.4 43.9 17.9 11.9 10.9 13.0 16.5 19.4 9.5 NDUFB9 "B22, LYRM3, UQOR22" ENSG00000147684 "NADH:ubiquinone oxidoreductase subunit B9" Q9Y6M9 8 124539101-124580648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1314.9;tongue: 1486.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 2950.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042768 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA042768: AB_10797508" "unprognostic (1.18e-2)" "unprognostic (2.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-3)" "unprognostic (8.32e-2)" "unprognostic (9.71e-2)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (3.80e-2)" "unprognostic (1.51e-1)" "unprognostic (3.64e-1)" "prognostic favorable (3.42e-5)" "unprognostic (9.54e-2)" "unprognostic (9.64e-2)" "unprognostic (4.94e-2)" "unprognostic (2.74e-1)" 155.6 158.2 259.0 78.5 263.8 265.2 157.8 281.1 381.2 109.7 245.0 226.4 184.6 129.5 147.4 209.2 126.0 70.4 789.5 257.6 288.7 324.9 325.0 122.9 96.5 279.3 277.8 107.1 209.4 282.9 124.0 81.2 281.5 117.8 191.0 135.8 210.9 115.1 1314.9 149.3 162.9 111.1 253.4 116.8 241.2 204.7 286.2 102.8 154.2 1486.4 104.1 139.9 124.7 274.1 348.2 316.8 236.1 321.2 240.6 204.2 196.0 165.2 189.3 297.4 222.4 417.7 327.6 341.0 421.0 193.6 153.9 385.5 347.3 266.7 279.9 395.8 464.8 831.3 199.6 505.9 320.8 261.8 218.2 239.6 382.1 271.9 587.9 160.1 275.9 241.1 523.7 277.6 243.4 1089.0 415.8 522.7 237.5 1247.0 692.7 276.3 179.9 468.0 400.0 288.8 326.6 255.0 362.4 2950.7 382.8 141.1 407.3 348.2 219.7 172.5 444.1 162.9 399.5 354.8 517.7 392.5 298.6 515.4 233.1 302.2 253.1 136.2 210.5 179.2 209.6 260.9 275.8 237.1 247.5 201.4 269.1 223.9 49.2 188.9 136.1 183.1 346.0 345.8 259.0 263.8 281.1 381.2 257.6 288.7 279.3 277.8 281.5 253.4 286.2 274.1 169.0 125.0 124.8 7.8 147.7 217.8 277.5 448.3 178.7 77.4 247.3 313.0 1005.6 260.2 267.3 286.9 98.0 494.6 119.9 525.0 800.3 338.0 389.8 120.7 100.6 164.1 233.7 227.6 10.5 405.7 296.0 187.9 169.7 109.2 139.4 149.9 167.4 517.7 380.6 37.0 14.9 421.0 488.3 206.0 137.6 865.4 158.8 183.0 247.3 15.9 226.3 144.1 171.0 7.1 18.2 378.1 450.0 152.7 169.1 290.3 584.6 789.7 208.6 91.1 170.9 221.2 511.8 317.6 264.8 377.0 188.4 523.0 155.6 216.0 521.7 315.8 NDUFS2 CI-49 ENSG00000158864 "NADH:ubiquinone oxidoreductase core subunit S2" O75306 1 161197104-161214723 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 464.8;tongue: 633.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055140, HPA061953" Enhanced Supported Mitochondria NA NA 25000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA055140: AB_2682713, HPA061953: AB_2684646" "unprognostic (2.13e-2)" "unprognostic (2.24e-2)" "unprognostic (8.47e-2)" "unprognostic (7.78e-2)" "unprognostic (9.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-2)" "unprognostic (1.51e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-2)" "unprognostic (3.17e-2)" "unprognostic (1.11e-1)" "prognostic favorable (2.32e-4)" "unprognostic (2.35e-1)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (1.82e-1)" 60.2 98.2 38.7 37.4 41.6 39.5 49.6 46.4 48.8 40.2 76.6 96.5 102.4 41.4 33.4 62.0 52.5 36.8 273.7 40.5 47.5 137.0 177.4 48.5 42.4 49.5 40.7 51.6 47.7 156.5 35.8 41.6 53.1 45.7 101.8 36.2 53.5 49.0 464.8 51.4 81.5 58.6 41.6 43.6 73.3 29.5 47.9 48.3 45.0 633.7 60.1 57.5 40.0 49.2 101.8 129.4 95.2 104.0 115.1 102.8 77.0 85.7 105.8 139.6 107.5 143.9 98.5 108.4 168.1 113.0 81.3 135.9 129.1 131.8 122.1 84.2 108.0 105.9 109.5 136.5 117.7 116.0 105.3 147.2 112.3 121.1 137.2 96.8 160.5 115.4 139.9 72.7 132.5 93.5 81.7 58.4 175.3 288.5 116.5 72.0 83.3 172.0 157.8 109.4 97.2 152.0 93.0 237.0 151.5 116.4 221.7 342.2 108.6 84.5 66.3 65.5 123.7 125.2 172.0 95.1 123.6 109.3 105.4 150.0 159.3 85.7 82.0 193.2 82.6 81.4 86.6 86.3 217.8 68.4 86.6 88.1 86.7 93.5 190.7 128.7 130.8 167.5 38.7 41.6 46.4 48.8 40.5 47.5 49.5 40.7 53.1 41.6 47.9 49.2 70.5 35.3 45.7 30.7 47.1 38.9 52.4 277.8 52.9 74.6 58.9 50.7 232.6 74.4 148.4 77.3 31.3 146.8 47.6 187.5 332.6 184.3 11.3 43.5 57.0 67.5 72.0 78.9 28.0 143.2 111.3 69.7 80.5 41.3 69.7 99.7 65.7 206.5 150.5 92.5 30.1 122.6 242.1 87.8 42.0 7.8 43.5 66.5 83.6 14.0 97.9 57.0 35.0 18.1 48.3 147.7 105.1 33.4 49.5 25.6 221.9 345.5 103.0 57.3 46.0 41.9 176.6 42.0 27.5 68.8 43.3 158.4 50.0 192.0 172.5 57.5 NENF "CIR2, SCIRP10, SPUF" ENSG00000117691 "Neudesin neurotrophic factor" Q9UMX5 1 212432920-212446379 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 512.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026763, HPA028488" Uncertain "Secreted to blood" NA NA 4000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA026763: AB_1854379, HPA028488: AB_2672638" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (2.49e-2)" "unprognostic (7.24e-2)" "unprognostic (7.41e-3)" "unprognostic (3.80e-3)" "unprognostic (5.35e-2)" "unprognostic (1.70e-2)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (4.99e-3)" "prognostic unfavorable (1.54e-6)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (4.28e-1)" "unprognostic (2.28e-2)" 63.9 53.4 132.2 16.8 149.0 26.9 65.7 141.3 188.1 82.8 137.7 53.8 19.8 59.8 70.2 45.9 58.3 23.9 141.0 130.9 138.5 70.0 62.7 45.4 16.4 142.5 142.7 82.7 68.7 64.1 148.1 29.4 143.2 69.4 36.1 22.7 72.4 50.5 95.0 55.6 35.2 44.7 142.7 33.6 47.7 16.7 138.3 23.0 57.6 104.5 25.6 58.0 57.7 156.0 78.8 65.3 26.6 103.2 155.3 116.6 38.9 39.5 94.5 67.5 65.7 74.0 49.8 36.0 29.0 93.0 68.4 49.7 55.1 56.0 55.1 45.7 107.2 26.5 39.9 24.4 59.3 25.1 66.2 83.9 82.5 47.8 40.0 76.1 44.1 54.1 60.2 39.0 60.5 40.2 45.4 95.3 39.0 73.9 137.9 42.1 62.6 50.2 70.3 23.1 43.2 77.5 59.2 89.6 74.0 40.4 70.8 75.2 9.1 54.9 49.0 76.8 73.3 36.2 62.6 26.9 57.5 36.0 43.0 0.9 4.8 2.1 3.9 7.1 6.9 8.1 4.7 8.8 7.8 5.3 6.1 6.2 0.5 0.9 5.0 13.5 5.8 2.5 132.2 149.0 141.3 188.1 130.9 138.5 142.5 142.7 143.2 142.7 138.3 156.0 124.8 12.8 21.6 14.0 72.0 166.2 233.0 10.8 173.6 44.0 322.5 418.5 152.9 163.0 13.4 248.3 12.5 291.4 64.3 101.0 164.4 50.9 5.3 40.7 119.1 87.4 135.8 135.0 11.9 49.0 182.0 219.7 65.7 58.4 47.1 45.7 145.3 211.8 189.3 38.7 12.6 143.7 6.1 149.4 198.1 23.9 297.6 127.2 186.7 11.2 69.2 329.6 34.0 21.6 80.5 32.7 70.7 223.8 136.0 322.9 56.1 512.7 7.6 28.4 118.3 162.1 233.9 13.3 138.5 158.8 170.6 184.4 70.4 61.8 157.0 264.5 NEURL4 KIAA1787 ENSG00000215041 "Neuralized E3 ubiquitin protein ligase 4" Q96JN8 17 7315628-7329393 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043678, HPA055314" Uncertain NA NA "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA043678: AB_10963092, HPA055314: AB_2682782" "unprognostic (4.38e-1)" "unprognostic (1.12e-1)" "unprognostic (4.70e-2)" "unprognostic (3.25e-3)" "unprognostic (1.63e-1)" "unprognostic (4.22e-2)" "unprognostic (4.78e-2)" "unprognostic (1.27e-1)" "unprognostic (1.85e-2)" "unprognostic (8.96e-3)" "prognostic favorable (2.34e-5)" "unprognostic (4.96e-2)" "unprognostic (3.72e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.47e-1)" "unprognostic (8.12e-2)" 7.3 6.7 2.6 3.3 3.1 3.0 7.9 1.2 4.2 10.7 0.6 11.9 3.9 11.4 1.7 7.0 10.3 2.4 9.0 3.1 1.2 7.9 5.7 6.9 3.9 1.8 1.6 12.8 8.7 4.6 12.3 2.3 1.5 10.0 1.8 2.5 8.4 3.3 18.8 9.4 9.8 2.4 0.3 9.3 8.6 9.8 1.6 3.8 12.4 5.2 2.3 10.0 8.6 2.4 3.3 11.5 7.3 11.7 4.4 2.8 8.7 5.0 3.2 6.0 4.9 8.0 2.7 10.2 5.1 3.0 4.9 9.4 7.8 4.7 2.6 5.5 12.3 5.1 13.2 4.7 3.0 5.0 6.9 2.7 4.8 6.2 3.5 4.7 3.8 8.5 7.3 2.1 2.6 4.2 7.5 9.3 5.1 3.9 5.6 12.9 5.8 4.1 3.7 3.4 6.8 5.7 5.2 5.2 2.0 3.7 4.4 3.5 4.8 5.5 4.2 4.6 5.6 4.3 2.9 4.3 3.5 4.6 5.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.1 1.2 4.2 3.1 1.2 1.8 1.6 1.5 0.3 1.6 2.4 3.4 0.0 2.2 10.4 2.4 2.5 0.8 2.3 0.6 11.4 4.9 5.3 1.6 4.3 2.3 5.5 14.6 2.3 1.9 5.4 1.9 2.5 2.0 4.3 4.1 2.9 4.2 2.1 8.4 1.4 1.8 2.1 8.2 3.8 2.5 6.4 4.6 3.4 2.6 5.0 7.0 5.0 4.1 2.5 1.8 1.6 2.8 3.5 0.0 4.7 1.9 3.1 5.2 4.5 6.4 2.4 2.1 1.9 2.0 1.6 5.1 5.8 2.5 8.7 0.0 2.7 3.7 4.2 4.5 3.4 2.8 1.9 2.5 3.2 5.7 0.6 NFKBIL1 "IKBL, NFKBIL" ENSG00000204498 "NFKB inhibitor like 1" Q9UBC1 6 31546870-31558829 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.8;HBEC3-KT: 5.0;HEK 293: 20.2;JURKAT: 9.8;U-266/70: 10.8;U-266/84: 9.6;U-698: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006298 Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA006298: AB_1079480" "unprognostic (1.11e-1)" "unprognostic (3.18e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.21e-1)" "unprognostic (3.63e-1)" "unprognostic (2.51e-2)" "unprognostic (6.29e-2)" "unprognostic (5.41e-2)" "unprognostic (5.97e-3)" "unprognostic (5.54e-2)" "unprognostic (1.33e-1)" "unprognostic (2.16e-1)" "unprognostic (8.73e-2)" "unprognostic (9.92e-2)" "unprognostic (3.15e-1)" "unprognostic (7.50e-2)" 20.4 18.3 0.0 0.5 0.0 0.0 21.5 0.0 0.3 22.8 0.0 26.9 0.0 21.1 2.2 17.5 22.3 0.0 19.4 0.0 0.0 20.8 23.4 16.7 0.0 0.0 0.0 33.0 42.8 0.0 23.9 0.0 0.0 24.3 0.0 0.4 19.8 0.0 27.6 24.2 16.5 0.0 0.0 19.4 30.4 17.4 0.0 0.0 23.4 0.0 0.0 23.1 19.4 0.1 0.0 4.0 0.0 0.1 4.4 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 2.8 0.0 0.0 5.0 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 9.6 5.9 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.2 0.2 0.9 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.7 6.4 3.6 7.8 14.9 20.8 26.7 31.4 30.1 18.8 25.6 25.5 5.7 25.8 12.8 25.8 2.1 21.8 13.2 23.1 39.2 27.0 8.7 15.9 14.6 18.4 7.8 9.2 5.6 31.8 28.1 19.6 25.5 12.9 7.0 25.2 24.3 15.8 24.4 6.7 6.1 27.1 14.2 29.3 16.1 8.9 25.4 17.4 8.8 1.9 26.2 26.8 24.7 3.5 5.2 32.7 22.4 25.9 8.3 24.3 61.4 24.8 13.0 17.9 26.3 20.2 30.9 12.7 10.0 17.4 18.8 29.6 11.6 30.7 26.2 22.3 NGF NGFB ENSG00000134259 "Nerve growth factor" P01138 1 115285904-115338770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 20.8;ovary: 18.9" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 15.7;Leydig cells: 29.2;Sertoli cells: 118.3;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in many" "renal cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 87.9;BJ hTERT+ SV40 Large T+: 30.1;GAMG: 46.2;hTEC/SVTERT24-B: 29.8;hTERT-RPE1: 49.0;U-2197: 60.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted in other tissues" NA NA 40000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "unprognostic (7.55e-2)" "unprognostic (2.66e-2)" "unprognostic (1.53e-3)" "unprognostic (8.85e-2)" "unprognostic (4.12e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (5.30e-2)" "unprognostic (8.73e-3)" "unprognostic (4.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.08e-7)" "unprognostic (1.15e-3)" "unprognostic (2.13e-1)" "unprognostic (7.99e-3)" "unprognostic (1.62e-4)" 13.9 2.5 1.7 1.6 1.7 0.0 4.0 1.3 2.1 7.1 2.1 5.0 0.1 8.8 1.4 1.1 13.2 1.7 20.8 1.6 2.2 6.4 4.0 1.6 0.5 1.9 1.7 18.9 0.8 0.4 2.7 1.1 1.9 2.6 0.6 0.1 2.1 1.0 0.9 0.9 2.1 4.0 1.4 3.7 2.1 1.1 1.9 0.2 3.3 1.1 0.1 5.5 5.0 1.6 0.0 0.3 0.0 0.0 1.8 0.1 0.0 87.9 9.9 30.1 21.9 0.0 0.0 0.0 1.9 21.1 46.2 3.6 0.0 0.6 13.8 0.0 0.2 0.0 0.6 0.0 12.1 0.0 0.0 0.1 0.6 29.8 21.6 49.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 3.0 0.0 1.3 0.0 1.2 0.0 0.0 0.0 1.1 0.3 1.6 0.6 0.0 3.9 0.0 0.0 0.8 1.8 3.7 60.0 3.5 0.0 0.0 0.0 3.6 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.7 1.3 2.1 1.6 2.2 1.9 1.7 1.9 1.4 1.9 1.6 0.4 0.0 0.0 0.3 0.0 3.1 0.5 3.9 0.0 0.0 0.1 1.5 0.7 1.5 0.2 0.0 0.0 3.0 0.0 0.0 0.0 5.6 0.2 0.2 0.8 0.8 0.0 0.0 0.3 0.0 1.3 7.3 0.0 0.3 0.0 0.0 4.2 0.0 0.1 0.0 15.7 0.0 2.0 0.0 1.7 0.4 29.2 0.2 1.8 1.9 0.0 0.0 0.0 12.1 0.5 0.1 0.0 6.0 0.0 0.6 0.0 0.0 0.1 0.0 118.3 0.8 51.6 0.3 1.0 0.0 2.3 2.5 0.6 0.0 0.0 0.3 NIPBL "DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, IDN3, Scc2" ENSG00000164190 "NIPBL cohesin loading factor" Q6KC79 5 36876769-37066413 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Activator, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 303.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040834, HPA058239" Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA040834: AB_10796562, HPA058239: AB_2683650" "unprognostic (4.92e-2)" "unprognostic (9.77e-2)" "unprognostic (5.28e-2)" "unprognostic (8.10e-2)" "unprognostic (9.38e-2)" "unprognostic (6.02e-2)" "unprognostic (7.34e-2)" "unprognostic (3.04e-2)" "unprognostic (3.85e-2)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" "unprognostic (3.41e-1)" "unprognostic (1.04e-1)" "unprognostic (3.40e-2)" 11.5 9.4 5.6 14.7 8.6 25.1 13.5 12.0 7.3 12.9 7.8 12.2 10.0 13.4 6.6 11.4 10.5 11.1 7.7 5.3 5.9 11.6 12.7 11.9 16.5 7.3 6.6 17.6 13.1 19.6 5.0 13.9 8.2 11.1 12.2 22.4 11.2 10.7 9.5 14.2 13.2 12.4 6.3 15.3 13.4 14.2 6.9 29.8 17.2 14.3 16.7 12.6 7.5 11.1 22.5 13.1 33.3 15.6 20.7 22.3 24.4 17.6 19.3 18.9 15.7 18.2 22.6 33.5 11.3 21.6 22.2 19.2 28.9 15.9 27.0 27.9 14.7 40.9 57.4 13.3 14.0 48.4 26.4 16.5 19.3 21.3 28.1 18.1 24.0 20.8 39.3 24.5 17.9 10.8 33.8 18.1 16.0 12.9 11.3 28.2 51.9 13.0 13.1 31.4 24.5 17.2 84.6 22.5 18.0 26.2 23.0 27.3 26.3 24.9 27.1 21.0 13.3 17.7 25.5 39.1 13.6 32.4 19.1 10.9 2.9 4.3 3.2 2.2 3.0 2.8 2.7 2.9 2.3 3.1 2.9 3.3 7.7 2.8 3.3 3.4 2.1 1.6 5.6 8.6 12.0 7.3 5.3 5.9 7.3 6.6 8.2 6.3 6.9 11.1 80.6 131.4 108.6 169.8 84.8 48.4 66.2 34.2 58.1 62.6 43.6 49.4 87.0 38.6 63.3 33.1 77.2 44.1 107.1 45.9 5.9 55.5 13.4 72.9 75.7 74.1 41.5 85.4 179.2 46.7 34.1 64.3 61.2 91.7 84.0 77.7 44.6 28.2 37.1 40.4 165.5 46.3 38.7 51.8 46.6 15.1 66.5 86.7 24.9 236.1 103.3 49.2 97.9 229.2 303.7 55.0 48.6 56.4 84.5 66.4 45.2 12.2 65.2 72.8 52.6 102.9 80.1 185.8 133.6 58.2 47.0 75.9 92.0 73.8 42.9 88.0 NMD3 CGI-07 ENSG00000169251 "NMD3 ribosome export adaptor" Q96D46 3 161104696-161253532 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035019 Supported Nucleoplasm,Nucleoli NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli" "HPA035019: AB_10600922" "unprognostic (1.37e-2)" "unprognostic (2.71e-1)" "unprognostic (9.50e-2)" "unprognostic (9.39e-3)" "unprognostic (1.95e-3)" "unprognostic (1.18e-2)" "unprognostic (1.03e-1)" "unprognostic (4.41e-2)" "unprognostic (2.00e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (2.03e-5)" "unprognostic (7.97e-2)" "unprognostic (5.57e-2)" "unprognostic (6.17e-2)" "unprognostic (8.71e-2)" "unprognostic (2.26e-2)" "unprognostic (5.86e-3)" 26.9 21.5 13.1 18.1 13.8 64.7 32.3 19.3 14.1 27.0 12.8 18.6 17.6 26.3 15.3 24.4 20.2 22.6 40.0 11.2 14.2 29.2 77.7 19.7 22.3 10.8 13.4 26.4 34.9 21.9 12.7 25.6 11.8 27.7 21.2 17.0 32.8 20.0 60.3 17.2 15.4 28.3 12.1 21.1 42.5 16.0 13.0 18.7 25.2 34.5 24.7 39.3 16.5 13.9 68.7 39.2 37.8 38.6 46.3 63.1 51.9 76.3 57.9 55.9 64.8 66.5 54.9 86.4 94.8 53.8 39.3 43.8 60.9 56.1 86.4 90.2 37.4 89.0 31.4 41.7 50.7 108.0 51.7 53.2 40.9 39.7 129.1 59.4 61.4 29.9 66.3 46.3 66.8 155.7 49.6 41.3 47.4 82.1 61.7 59.8 54.5 87.9 53.1 153.2 59.8 37.3 43.5 105.2 63.9 40.9 78.3 49.0 54.2 44.1 31.5 51.3 93.4 75.6 54.5 87.1 55.5 69.5 61.5 30.5 16.6 8.9 16.5 17.6 25.9 17.3 19.2 20.4 19.8 15.6 25.3 20.1 3.6 35.4 11.4 11.0 26.8 20.7 13.1 13.8 19.3 14.1 11.2 14.2 10.8 13.4 11.8 12.1 13.0 13.9 30.6 19.2 14.6 22.9 25.3 64.9 52.9 23.8 34.7 24.7 26.8 16.5 43.9 21.5 25.1 11.0 14.6 33.3 25.2 14.0 35.2 25.6 19.3 13.8 29.6 30.1 13.8 32.2 16.6 38.9 48.8 34.0 31.1 19.3 25.4 20.3 22.1 41.6 23.4 30.3 15.3 19.4 26.4 33.1 47.0 7.0 25.4 21.6 24.9 12.2 26.1 12.8 21.6 19.6 18.2 33.0 13.9 27.4 20.9 46.7 19.7 39.9 18.5 20.8 26.3 29.1 87.5 39.2 27.4 33.4 74.3 56.6 25.8 24.4 21.2 72.7 NME1 "NDPKA, NM23, NM23-H1" ENSG00000239672 "NME/NM23 nucleoside diphosphate kinase 1" P15531 17 51153559-51162428 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Endocytosis, Neurogenesis, Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008467, CAB040571, HPA041113" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 21000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "CAB040571: , HPA008467: AB_1079492, HPA041113: AB_2677305" "unprognostic (2.24e-1)" "unprognostic (2.01e-1)" "unprognostic (3.48e-3)" "unprognostic (5.96e-2)" "unprognostic (9.71e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (2.60e-5)" "unprognostic (4.54e-2)" "unprognostic (3.35e-1)" "unprognostic (2.33e-3)" "unprognostic (2.90e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.07e-9)" "unprognostic (9.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.83e-1)" "unprognostic (9.46e-2)" 63.6 84.4 79.3 74.7 81.6 77.0 63.1 78.7 102.2 38.2 79.0 60.1 38.8 49.7 46.8 91.0 48.6 20.8 37.7 88.0 92.0 65.4 83.2 41.3 73.9 83.9 78.4 33.6 67.8 52.8 47.4 39.2 82.4 38.7 77.6 218.4 50.7 30.4 35.6 57.5 33.1 66.3 76.5 48.5 41.8 25.3 81.0 61.1 41.3 20.9 95.8 72.2 48.9 80.1 483.6 833.1 285.9 444.8 118.6 183.7 479.7 355.3 227.3 652.2 489.7 656.9 288.1 754.2 372.4 304.1 272.4 252.1 542.5 553.3 553.4 398.4 729.3 504.9 605.8 975.9 237.1 575.8 243.8 177.8 341.7 493.1 458.6 120.6 404.6 247.8 739.0 270.0 392.8 720.4 715.2 647.1 390.7 957.5 739.3 446.9 587.6 751.3 511.5 320.2 418.6 461.1 188.1 521.0 385.3 246.2 554.0 419.6 279.5 476.9 452.2 307.0 774.4 374.0 840.9 956.3 286.2 480.4 385.8 1.1 55.0 2.1 47.2 77.1 69.3 96.4 50.3 53.8 134.0 67.6 54.3 60.4 1.7 69.6 48.6 84.8 49.1 68.4 79.3 81.6 78.7 102.2 88.0 92.0 83.9 78.4 82.4 76.5 81.0 80.1 53.1 32.1 30.5 0.0 71.3 132.4 97.5 198.8 88.8 283.3 98.8 118.1 34.2 65.8 92.3 71.7 285.7 180.0 25.4 54.2 150.6 211.3 34.2 40.2 107.2 85.1 89.7 81.8 0.0 201.5 269.7 85.0 64.2 37.2 45.7 113.5 27.8 123.3 207.1 40.4 0.0 107.4 101.7 25.7 88.9 93.7 61.2 48.9 129.9 0.0 47.2 105.6 27.8 0.0 0.0 194.0 50.5 58.6 113.8 170.6 12.2 195.2 42.0 323.7 13.1 83.0 182.9 22.7 98.8 139.4 133.1 88.5 38.0 215.5 157.7 98.2 NONO "NMT55, NRB54, P54, P54NRB, PPP1R114" ENSG00000147140 "Non-POU domain containing octamer binding" Q15233 X 71254814-71301522 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022069, HPA054094, HPA054559" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Nuclear speckles" NA NA 450000 "Cluster 44: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Nuclear speckles" "CAB022069: , HPA054094: AB_2682376, HPA054559: AB_2682522" "unprognostic (2.39e-3)" "unprognostic (2.22e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (8.87e-2)" "unprognostic (5.54e-2)" "unprognostic (1.02e-3)" "unprognostic (9.34e-2)" "unprognostic (2.32e-2)" "unprognostic (1.41e-2)" "unprognostic (3.12e-1)" "unprognostic (2.07e-1)" "unprognostic (7.29e-3)" "unprognostic (6.79e-2)" "unprognostic (5.73e-3)" "unprognostic (2.76e-2)" "unprognostic (3.04e-2)" 106.4 147.2 58.6 96.4 57.7 115.3 109.2 71.5 64.9 116.8 64.4 101.3 86.2 130.2 107.9 111.9 115.4 100.7 81.2 55.3 69.9 103.3 121.5 103.2 136.5 60.3 61.5 197.9 164.8 114.8 97.1 99.1 60.5 97.0 101.2 70.2 106.8 89.6 99.1 112.2 102.0 113.5 59.2 109.5 114.3 55.2 68.5 255.5 116.0 86.1 165.2 116.8 102.6 61.0 421.2 539.7 595.3 344.4 251.2 238.5 345.3 330.9 319.2 459.3 388.5 413.4 312.9 481.4 379.9 320.5 309.7 310.5 949.5 299.4 488.1 383.9 605.7 394.8 498.4 398.0 212.3 547.7 338.7 272.0 206.0 473.1 305.7 370.5 382.0 342.1 535.3 509.0 406.2 413.9 756.0 466.8 771.3 433.9 365.2 660.0 657.3 414.0 345.9 426.1 431.7 519.4 467.8 299.1 392.5 354.9 271.4 354.0 343.9 268.0 438.6 402.9 400.1 297.3 503.2 516.0 216.8 627.1 433.8 107.5 117.3 91.1 107.9 120.0 119.9 107.4 107.9 106.4 118.7 107.2 115.1 115.6 50.8 119.6 140.7 101.1 128.0 178.1 58.6 57.7 71.5 64.9 55.3 69.9 60.3 61.5 60.5 59.2 68.5 61.0 72.9 76.9 81.1 16.3 97.2 126.3 99.9 105.8 116.7 62.3 111.4 83.6 63.5 90.1 99.8 44.1 41.7 132.3 103.6 52.0 56.7 147.8 11.8 81.6 137.8 95.4 139.8 144.6 16.2 111.4 179.9 93.9 71.4 104.8 88.0 135.9 83.9 128.3 112.6 53.8 20.7 105.6 95.6 153.2 107.7 15.9 106.6 95.0 56.9 13.1 132.0 84.8 96.8 19.6 22.8 110.7 75.4 127.9 115.2 94.9 89.0 121.0 71.1 50.3 65.7 78.7 127.8 45.7 66.5 137.3 122.3 130.1 108.5 163.7 117.2 103.0 NOP10 "MGC70651, NOLA3, NOP10P" ENSG00000182117 "NOP10 ribonucleoprotein" Q9NPE3 15 34341719-34343136 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 878.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059198 Supported Supported "Nuclear bodies" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 52: Non-specific - Ribosome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" "HPA059198: AB_2683945" "unprognostic (2.65e-1)" "unprognostic (1.72e-2)" "unprognostic (1.08e-1)" "prognostic favorable (1.48e-5)" "unprognostic (3.12e-1)" "unprognostic (2.39e-3)" "unprognostic (8.11e-3)" "unprognostic (9.99e-2)" "unprognostic (2.28e-1)" "unprognostic (8.31e-3)" "unprognostic (1.77e-3)" "unprognostic (1.76e-1)" "unprognostic (1.83e-3)" "unprognostic (2.61e-1)" "unprognostic (2.59e-1)" "unprognostic (1.05e-1)" "unprognostic (6.77e-3)" 154.9 145.7 119.9 104.8 122.2 208.3 151.7 124.3 149.6 118.6 120.1 164.3 109.3 91.9 285.5 175.0 120.0 90.2 179.4 120.7 129.1 167.7 241.1 148.0 146.2 125.3 123.2 63.3 90.4 142.5 90.5 126.8 125.6 98.2 202.1 48.4 93.6 102.2 184.4 114.4 110.2 163.6 125.1 167.5 119.0 41.7 132.7 213.2 112.8 227.4 218.6 213.6 121.2 132.8 212.2 471.9 325.1 205.3 520.4 443.7 172.4 281.3 471.8 555.4 703.6 358.5 200.3 146.7 328.6 457.7 627.3 292.8 599.1 502.8 526.0 216.0 341.7 461.6 396.5 523.7 724.2 303.2 228.6 513.8 471.0 508.3 588.1 305.0 795.6 399.9 417.0 206.4 695.3 295.8 234.0 486.1 319.8 628.7 453.3 252.2 223.4 241.8 754.0 475.5 210.4 279.5 202.1 211.7 221.4 442.9 235.4 619.4 331.2 295.3 219.6 418.2 242.7 198.9 427.1 406.8 377.5 495.8 214.5 1080.4 852.4 889.6 368.7 867.8 394.9 723.0 476.7 442.7 636.3 639.5 503.6 441.2 2797.7 534.1 696.7 824.6 700.1 1065.2 119.9 122.2 124.3 149.6 120.7 129.1 125.3 123.2 125.6 125.1 132.7 132.8 202.7 109.0 153.3 7.2 175.1 239.5 179.8 470.8 130.3 30.9 158.6 195.2 299.7 143.0 273.9 149.0 12.5 210.7 158.0 286.1 446.1 365.6 15.0 230.7 148.1 257.5 195.7 169.5 6.7 351.9 402.1 154.2 122.9 234.0 164.0 81.3 240.9 359.7 878.9 13.5 7.1 283.9 315.3 504.5 321.5 16.8 103.8 309.2 190.3 12.2 322.1 70.0 250.3 5.0 10.0 600.6 362.9 100.1 209.5 251.2 304.2 668.9 298.6 33.7 105.2 91.7 336.0 19.0 101.8 224.8 302.8 214.0 154.2 128.7 241.0 451.3 NOP14 "C4orf9, NOL14, RES4-25, UTP2" ENSG00000087269 "NOP14 nucleolar protein" P78316 4 2937933-2963406 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039596, HPA055652" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoli Nucleoplasm "HPA039596: AB_2676590, HPA055652: AB_2682876" "unprognostic (4.70e-2)" "unprognostic (6.47e-2)" "prognostic favorable (3.93e-5)" "unprognostic (7.32e-2)" "unprognostic (3.28e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (9.10e-4)" "unprognostic (2.41e-2)" "unprognostic (8.62e-2)" "unprognostic (2.09e-1)" "unprognostic (1.30e-1)" "unprognostic (2.55e-3)" "unprognostic (1.16e-1)" "unprognostic (1.27e-3)" "unprognostic (1.44e-1)" "unprognostic (7.15e-2)" "unprognostic (4.77e-2)" 17.5 15.7 4.6 18.4 5.9 22.9 16.5 11.2 5.1 13.2 6.9 13.7 12.4 13.2 6.0 18.3 12.2 9.3 13.0 4.3 5.8 11.5 19.0 12.4 23.4 5.5 5.4 19.2 24.6 11.1 11.0 12.1 5.6 11.6 12.7 7.1 13.9 9.0 41.7 22.3 13.6 11.5 4.6 15.2 15.4 7.7 6.1 15.7 15.5 14.6 19.7 19.8 14.6 6.8 52.7 43.8 25.6 52.9 33.6 37.9 44.6 47.4 33.5 48.2 39.6 57.5 54.1 148.0 32.8 38.7 35.1 35.5 71.1 61.5 51.6 28.4 67.8 117.8 40.5 52.6 44.3 129.3 49.2 38.6 54.2 54.7 49.5 23.9 41.3 44.6 108.7 50.9 37.0 37.7 137.4 94.4 66.6 48.0 70.7 87.8 38.7 49.3 24.1 83.2 52.6 30.9 39.4 28.8 37.9 23.0 55.0 50.3 51.7 40.3 23.3 49.6 88.3 37.9 65.8 124.8 41.9 93.6 42.6 1.0 2.1 0.4 2.8 2.4 4.9 2.1 3.4 4.3 2.5 3.5 4.1 3.1 0.2 3.2 1.6 3.1 2.5 2.1 4.6 5.9 11.2 5.1 4.3 5.8 5.5 5.4 5.6 4.6 6.1 6.8 13.3 19.2 30.5 3.6 22.2 25.9 23.4 11.6 27.9 9.6 12.2 12.2 20.2 12.8 23.9 1.8 14.6 16.8 21.0 11.8 11.7 19.5 2.6 13.6 27.8 16.5 9.0 22.3 4.7 24.0 18.4 16.3 20.9 16.4 20.8 25.9 8.6 24.3 11.0 20.2 5.7 11.6 4.1 7.0 12.1 2.6 12.5 14.6 0.0 3.7 15.3 6.3 10.3 3.0 4.7 21.3 6.5 9.8 28.1 27.1 5.1 14.1 12.0 7.7 13.1 23.3 19.7 11.8 19.1 32.5 32.5 11.5 24.1 38.5 17.0 21.4 NOP56 "NOL5A, SCA36" ENSG00000101361 "NOP56 ribonucleoprotein" O00567 20 2652593-2658393 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" Ribonucleoprotein "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049918, CAB075757" Supported Enhanced "Nucleoli fibrillar center" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli fibrillar center" "CAB075757: AB_2665763, HPA049918: AB_2680952" "unprognostic (2.82e-1)" "unprognostic (2.97e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.01e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.59e-7)" "unprognostic (2.63e-2)" "prognostic unfavorable (6.77e-4)" "unprognostic (7.11e-2)" "unprognostic (2.59e-2)" "unprognostic (9.87e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (1.04e-2)" "unprognostic (2.53e-1)" "unprognostic (1.12e-2)" "unprognostic (2.42e-1)" 41.4 31.3 39.9 42.6 39.7 60.4 37.1 38.8 59.7 30.9 35.3 33.8 28.8 39.9 34.7 37.1 50.7 26.3 30.9 41.1 45.8 29.8 30.5 25.9 53.5 40.4 40.6 49.7 38.6 27.1 31.5 37.4 43.4 31.1 39.9 21.0 27.1 35.6 43.2 38.4 28.1 52.0 39.9 37.7 25.9 28.3 45.4 51.9 33.4 29.2 62.2 52.4 28.4 44.4 152.8 147.3 108.4 108.0 122.8 89.8 184.2 150.4 97.3 198.3 134.9 204.3 122.2 330.5 82.7 104.2 117.7 253.3 287.5 221.4 196.6 93.5 171.4 195.0 76.0 225.3 125.9 179.4 91.3 123.6 137.2 254.8 260.4 78.2 117.4 153.1 215.7 151.2 138.1 103.1 317.8 214.1 233.8 270.9 180.9 257.2 156.2 188.5 120.8 146.7 115.5 101.1 171.0 193.4 302.8 115.7 167.6 152.7 91.6 170.2 115.9 132.6 227.2 91.9 186.0 274.0 45.9 209.4 128.5 5.1 23.2 18.9 33.0 26.4 41.1 35.8 35.9 36.6 23.6 32.4 34.0 34.0 1.8 33.6 19.8 41.1 33.4 24.8 39.9 39.7 38.8 59.7 41.1 45.8 40.4 40.6 43.4 39.9 45.4 44.4 75.0 44.8 59.8 14.0 89.3 96.4 103.6 76.4 88.2 39.5 62.9 78.6 39.0 42.9 100.1 23.9 62.6 117.5 132.2 71.8 25.4 78.2 8.0 64.6 100.6 73.3 72.3 93.2 24.6 86.5 124.2 87.5 44.4 48.5 79.1 97.5 52.5 40.9 86.9 50.5 24.1 81.2 54.9 46.8 45.9 14.0 57.2 57.5 30.2 12.2 64.9 32.8 80.3 18.1 21.5 75.6 34.6 54.9 79.6 92.0 38.7 53.8 81.2 37.6 26.3 110.0 141.5 50.3 185.9 89.1 81.7 56.5 102.6 99.4 110.0 58.0 NOP58 "HSPC120, NOP5" ENSG00000055044 "NOP58 ribonucleoprotein" Q9Y2X3 2 202265736-202303661 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018472, HPA021062" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli fibrillar center" Nucleoplasm "HPA018472: AB_1854564, HPA021062: AB_1854565" "unprognostic (1.56e-2)" "unprognostic (1.61e-1)" "unprognostic (9.20e-2)" "unprognostic (2.15e-3)" "unprognostic (2.39e-1)" "unprognostic (3.94e-2)" "prognostic unfavorable (1.97e-6)" "unprognostic (6.64e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.86e-4)" "unprognostic (4.52e-3)" "unprognostic (5.20e-2)" "prognostic unfavorable (3.38e-9)" "unprognostic (1.79e-2)" "unprognostic (3.10e-1)" "unprognostic (1.33e-1)" "unprognostic (2.60e-1)" 36.0 35.1 33.5 43.9 33.6 76.3 43.7 38.8 58.4 29.5 33.4 30.4 28.2 32.2 33.4 37.8 31.6 23.6 25.1 33.4 36.3 32.8 40.7 26.4 60.3 32.3 33.3 37.4 37.8 24.8 30.2 32.6 32.6 29.5 35.8 28.1 26.5 23.1 41.8 30.7 29.7 27.3 32.6 33.9 29.6 24.9 34.8 41.9 27.1 21.5 59.8 43.3 30.2 35.3 126.4 86.0 85.1 106.8 62.0 55.6 199.2 118.5 62.9 89.1 82.9 191.5 110.9 193.1 95.4 72.5 111.6 114.0 170.1 144.7 158.4 75.0 152.5 233.6 133.3 193.7 91.5 234.7 108.6 72.1 85.3 124.6 284.6 48.6 81.2 112.3 260.4 144.1 113.4 131.4 215.1 258.7 212.9 139.4 146.5 179.5 128.3 257.1 107.1 148.5 130.5 95.8 109.0 156.6 140.8 136.2 106.4 181.8 70.3 113.5 133.8 102.5 206.0 115.7 226.1 274.8 84.2 163.7 138.5 13.4 24.0 7.4 37.2 35.6 55.0 56.1 53.1 51.2 37.4 45.0 57.5 58.9 2.3 52.1 28.3 53.1 58.0 32.5 33.5 33.6 38.8 58.4 33.4 36.3 32.3 33.3 32.6 32.6 34.8 35.3 56.3 109.0 116.2 22.2 111.6 85.8 150.5 98.0 78.0 28.1 53.8 70.2 82.7 37.1 116.8 40.5 41.7 78.1 87.1 35.7 29.4 59.9 39.2 59.6 75.9 62.3 35.2 65.2 39.0 67.8 96.9 82.6 51.0 97.0 137.3 47.7 32.2 46.1 47.7 25.2 47.5 61.5 61.1 23.2 43.5 11.1 43.2 51.5 24.9 20.6 59.6 18.8 35.0 20.6 27.0 50.3 17.3 29.7 118.6 89.9 18.3 37.8 70.6 44.2 26.3 112.2 116.8 70.4 58.4 77.5 74.7 68.0 124.1 45.4 79.6 94.6 NSFL1C "dJ776F14.1, p47, UBX1, UBXD10, UBXN2C" ENSG00000088833 "NSFL1 cofactor" Q9UNZ2 20 1442162-1473842 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047108, HPA050628" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 1900000 "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA047108: AB_2679935, HPA050628: AB_2681194" "unprognostic (7.55e-2)" "unprognostic (5.26e-2)" "unprognostic (2.51e-2)" "unprognostic (2.47e-1)" "unprognostic (5.96e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.10e-2)" "unprognostic (1.59e-1)" "unprognostic (4.67e-2)" "unprognostic (2.58e-1)" "unprognostic (4.97e-2)" "unprognostic (6.90e-2)" "unprognostic (5.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.44e-2)" "unprognostic (7.50e-3)" 22.8 37.7 38.3 13.5 39.5 27.8 21.5 37.0 45.9 23.2 41.6 23.0 14.9 22.5 26.8 28.5 26.1 13.5 29.1 39.7 38.6 21.4 26.3 18.0 15.2 39.0 39.0 25.7 15.5 23.9 14.1 21.1 39.8 20.9 18.4 22.6 19.3 26.4 69.0 36.6 17.6 22.9 36.4 19.8 18.0 14.8 38.6 21.0 20.0 43.3 18.6 22.4 21.6 39.7 55.6 64.4 35.9 32.0 30.5 31.4 28.7 21.0 41.8 57.7 41.3 53.9 43.1 31.6 16.6 47.8 47.2 50.4 25.9 70.3 40.8 12.3 25.1 29.8 10.3 61.4 33.8 30.7 16.4 23.5 33.3 55.3 20.3 30.8 46.8 23.4 42.5 26.5 36.2 29.1 31.4 54.7 40.7 42.5 65.4 14.7 41.1 29.8 68.6 37.1 20.5 23.4 29.6 59.8 26.7 18.8 36.5 22.0 37.8 38.7 29.4 23.9 40.2 21.9 41.8 24.7 28.9 43.0 29.3 31.4 21.3 80.3 20.0 26.6 19.7 35.0 21.2 19.5 29.7 36.0 23.4 20.7 69.1 16.7 28.1 23.1 28.2 25.5 38.3 39.5 37.0 45.9 39.7 38.6 39.0 39.0 39.8 36.4 38.6 39.7 34.6 22.4 23.2 17.3 36.1 89.2 63.5 106.3 44.3 60.2 28.6 26.0 35.4 24.3 57.8 31.3 22.9 150.7 29.7 68.2 56.7 104.7 23.0 51.0 29.6 44.3 43.6 41.0 24.0 94.5 146.0 41.1 30.5 54.9 40.5 49.1 31.1 42.2 81.1 70.7 24.8 42.5 61.1 43.7 43.6 38.8 39.1 43.8 42.7 14.0 52.9 61.7 32.0 17.6 31.2 123.4 65.7 46.3 41.8 76.0 66.4 73.8 43.2 44.5 78.9 44.2 64.7 106.1 103.2 55.1 75.7 151.6 31.6 48.9 44.0 88.5 NUP43 "bA350J20.1, FLJ13287" ENSG00000120253 "Nucleoporin 43" Q8NFH3 6 149724315-149749665 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027126, HPA027291, HPA028500" Enhanced Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" Cytosol "HPA027126: AB_10599301, HPA027291: AB_10601851, HPA028500: AB_10602287" "prognostic unfavorable (2.08e-4)" "unprognostic (3.02e-1)" "unprognostic (3.86e-2)" "unprognostic (1.45e-3)" "unprognostic (2.29e-1)" "unprognostic (8.19e-3)" "prognostic unfavorable (7.13e-7)" "unprognostic (5.14e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-1)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-2)" "unprognostic (6.25e-3)" "unprognostic (2.02e-1)" "unprognostic (2.72e-2)" "unprognostic (3.60e-2)" 8.4 8.6 6.2 11.4 7.5 6.2 13.6 7.2 6.9 9.7 6.5 9.4 8.7 9.8 7.5 9.5 8.2 6.4 10.8 5.6 6.6 9.9 9.6 8.0 15.9 6.6 6.6 9.1 12.2 8.9 5.6 11.4 6.9 10.3 9.7 9.8 8.8 9.2 14.2 13.5 10.9 9.4 6.6 13.6 9.8 7.9 6.5 12.8 11.1 11.6 17.0 9.0 9.1 8.3 21.1 34.9 31.1 49.6 20.0 23.7 48.9 36.3 20.3 34.0 43.0 49.5 19.5 61.4 36.6 20.2 32.1 33.5 54.6 31.6 58.3 27.8 38.2 70.9 35.5 49.6 13.4 73.2 44.1 15.3 16.4 49.9 33.1 13.0 27.5 34.6 71.4 33.6 29.6 20.7 52.2 30.4 28.3 24.1 21.0 50.2 43.2 20.6 23.2 28.9 12.9 21.2 43.4 27.1 14.2 25.6 28.7 30.9 21.3 28.3 30.2 41.2 53.9 20.5 43.3 63.9 25.2 49.3 40.5 2.9 4.9 3.4 3.5 5.4 3.8 4.3 4.2 3.5 2.6 6.2 4.3 5.5 1.9 3.7 4.8 5.0 4.9 2.2 6.2 7.5 7.2 6.9 5.6 6.6 6.6 6.6 6.9 6.6 6.5 8.3 5.8 3.2 7.8 9.1 11.5 7.9 5.5 4.7 2.8 11.9 4.5 5.0 14.3 11.5 5.2 3.7 6.2 10.9 11.3 4.7 3.9 9.0 33.3 4.3 8.7 5.7 10.2 7.6 4.8 7.8 12.2 6.4 6.1 6.0 0.0 12.8 8.2 4.4 7.8 6.7 5.1 6.9 2.0 11.9 6.9 78.9 10.2 6.5 8.8 9.4 15.1 10.5 9.2 11.1 17.4 6.6 2.3 10.5 8.7 6.2 3.9 5.4 4.2 9.5 13.1 6.9 22.1 7.1 9.2 5.5 8.5 6.6 7.6 7.4 8.4 6.7 NUP85 "FLJ12549, NUP75" ENSG00000125450 "Nucleoporin 85" Q9BW27 17 75205659-75235758 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061910, HPA062595" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA061910: AB_2684634, HPA062595: AB_2684801" "unprognostic (2.30e-1)" "unprognostic (5.10e-2)" "unprognostic (5.12e-3)" "unprognostic (2.52e-3)" "unprognostic (2.25e-1)" "unprognostic (1.01e-2)" "prognostic unfavorable (1.73e-7)" "unprognostic (3.46e-1)" "unprognostic (1.09e-2)" "unprognostic (9.93e-2)" "unprognostic (2.94e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (1.03e-3)" "unprognostic (2.16e-1)" "unprognostic (9.10e-3)" "unprognostic (2.11e-1)" 20.9 12.9 15.2 18.6 15.7 20.8 20.0 21.8 17.0 21.5 15.4 18.7 15.8 20.8 16.1 20.5 20.9 11.6 16.4 15.6 14.7 18.9 22.1 18.7 26.5 15.8 15.1 20.8 18.7 12.1 12.7 19.0 16.0 18.9 21.0 11.2 16.7 14.3 16.7 23.9 20.5 19.6 14.9 25.3 16.9 22.2 15.3 33.2 18.0 14.1 27.0 17.9 19.5 17.0 66.5 74.0 53.4 37.3 20.3 31.5 74.0 47.3 37.4 108.5 101.7 63.2 61.4 61.1 26.6 41.1 70.5 55.9 88.8 50.6 96.1 19.3 70.1 51.0 83.3 56.3 16.6 52.8 40.7 30.3 30.5 76.1 32.8 24.9 84.7 49.0 63.3 38.1 53.8 73.0 100.2 64.8 40.0 82.2 67.4 68.9 115.1 55.5 42.1 47.5 40.6 38.5 58.2 73.7 42.5 59.4 83.3 59.1 30.8 80.2 74.4 52.5 76.3 23.6 21.0 79.2 41.4 47.3 50.6 8.1 24.9 21.5 16.1 22.6 22.9 16.1 17.5 15.9 20.5 21.5 17.0 12.8 8.2 16.7 16.5 22.5 16.6 17.3 15.2 15.7 21.8 17.0 15.6 14.7 15.8 15.1 16.0 14.9 15.3 17.0 13.2 6.4 12.5 7.2 13.9 6.1 8.9 19.1 6.2 7.8 10.3 7.5 9.0 8.6 15.0 7.3 10.4 23.0 11.7 9.1 7.9 16.0 3.7 11.1 13.6 15.0 7.7 16.2 13.5 19.4 22.1 13.8 9.7 10.3 11.4 13.0 21.0 23.1 23.0 6.7 9.9 11.0 16.2 13.3 7.2 3.9 14.3 13.7 8.8 10.3 15.8 4.8 22.6 3.5 10.6 18.3 7.5 9.8 8.6 7.9 8.8 11.7 11.8 8.8 32.9 7.9 19.2 24.9 29.3 7.3 7.1 12.7 10.9 7.4 13.3 8.0 NUP88 MGC8530 ENSG00000108559 "Nucleoporin 88" Q99567 17 5360963-5419676 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 146.0;Spermatocytes: 147.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002209, HPA021816" Approved Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB002209: AB_564128, HPA021816: AB_1854725" "unprognostic (3.46e-2)" "unprognostic (1.66e-2)" "unprognostic (1.04e-2)" "unprognostic (8.83e-2)" "unprognostic (1.05e-1)" "unprognostic (2.03e-1)" "unprognostic (3.38e-2)" "unprognostic (3.94e-1)" "unprognostic (4.72e-2)" "unprognostic (4.94e-2)" "unprognostic (2.04e-2)" "unprognostic (5.75e-3)" "unprognostic (1.49e-1)" "unprognostic (1.10e-1)" "unprognostic (9.03e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" 11.8 12.0 4.2 16.3 3.8 20.8 15.2 7.5 6.0 10.8 3.3 13.2 9.9 10.4 16.4 12.1 12.4 8.0 12.2 3.9 3.9 15.2 27.3 9.4 26.4 4.1 4.0 8.5 10.2 15.3 9.0 10.9 4.3 11.5 19.3 9.6 13.2 10.3 31.2 12.9 11.7 13.7 3.6 14.8 12.3 49.3 3.8 24.1 14.6 21.6 32.9 15.1 9.0 4.2 46.2 50.0 44.0 33.3 18.3 20.0 40.2 35.8 29.0 58.7 52.0 41.5 17.8 88.6 13.3 33.1 38.1 43.5 73.6 39.6 74.7 22.7 48.6 40.0 42.7 32.5 24.8 31.8 34.6 14.3 28.2 43.7 71.3 24.5 41.0 34.3 42.3 22.2 46.5 24.3 46.7 23.4 41.2 46.4 23.9 44.1 48.5 38.7 30.7 22.3 17.5 33.9 44.0 20.4 28.1 33.7 22.9 37.3 26.8 26.4 28.3 27.1 66.9 15.0 19.4 39.5 31.3 36.3 37.4 5.4 7.6 4.3 12.4 12.2 12.3 39.1 13.3 15.0 10.9 35.7 14.3 15.9 0.9 21.1 14.3 12.2 17.6 11.5 4.2 3.8 7.5 6.0 3.9 3.9 4.1 4.0 4.3 3.6 3.8 4.2 6.9 12.8 17.8 10.1 38.0 22.2 31.5 13.5 14.2 13.3 8.9 6.2 10.7 11.5 18.1 16.5 16.7 30.1 19.3 15.2 11.7 27.9 146.0 26.1 15.0 11.5 13.8 28.6 22.9 25.4 24.8 12.2 15.3 47.2 7.6 14.9 9.3 16.5 11.4 10.1 20.4 10.1 14.2 7.9 12.3 38.0 15.2 10.6 3.6 11.2 19.4 7.8 26.8 13.0 17.8 23.3 15.4 10.9 9.4 21.7 9.9 7.5 11.5 11.0 13.1 19.5 20.5 147.5 61.8 15.8 17.0 36.0 17.9 13.6 17.6 42.8 NUP93 KIAA0095 ENSG00000102900 "Nucleoporin 93" Q8N1F7 16 56730118-56850286 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017937 Uncertain NA NA 38000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA017937: AB_1854726" "unprognostic (6.31e-2)" "unprognostic (3.22e-2)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (3.99e-3)" "unprognostic (2.78e-3)" "prognostic unfavorable (1.72e-6)" "unprognostic (9.18e-2)" "unprognostic (9.35e-3)" "unprognostic (5.22e-2)" "unprognostic (4.55e-2)" "unprognostic (1.97e-1)" "unprognostic (2.66e-2)" "unprognostic (3.71e-1)" "unprognostic (1.85e-1)" "unprognostic (9.68e-2)" "unprognostic (3.74e-2)" 17.9 13.9 13.2 21.3 17.4 52.7 15.5 6.8 23.9 15.3 0.2 17.7 9.9 16.9 12.4 22.3 15.3 12.4 14.2 30.6 10.7 12.8 9.3 15.3 27.7 10.7 9.3 14.9 14.2 14.8 10.8 19.1 9.9 17.7 18.1 31.7 12.2 12.7 20.0 21.6 14.5 19.5 8.3 24.2 15.2 39.8 11.4 34.1 34.3 14.2 30.3 17.1 16.1 11.5 71.3 84.5 71.6 81.0 25.9 34.8 81.0 58.7 48.2 156.2 100.1 119.4 66.1 107.7 60.4 54.9 54.2 120.6 143.3 90.1 149.8 34.0 81.3 72.6 64.7 97.3 35.0 96.7 82.8 29.3 35.7 104.2 64.7 31.6 90.8 95.3 87.8 22.3 72.3 52.4 136.2 81.1 92.1 44.2 95.4 163.9 129.4 108.9 53.1 47.8 66.6 44.1 159.1 54.6 47.3 77.4 43.0 57.9 55.3 68.1 74.0 57.8 67.5 35.0 60.7 190.2 47.4 88.5 67.5 19.3 49.9 195.7 38.9 77.2 45.2 45.4 28.3 40.9 60.9 45.4 28.7 41.0 11.8 51.8 77.5 28.7 39.7 47.4 13.2 17.4 6.8 23.9 30.6 10.7 10.7 9.3 9.9 8.3 11.4 11.5 11.3 6.4 12.3 17.6 13.4 12.0 13.6 20.7 6.2 68.6 9.0 7.6 11.8 1.5 20.2 9.2 10.4 21.1 9.4 8.6 11.7 24.6 11.7 10.9 8.8 16.5 4.9 33.2 51.1 25.5 31.7 12.8 13.7 10.6 17.2 22.3 10.8 7.2 26.6 38.7 49.4 11.2 24.4 17.8 23.8 7.7 23.3 17.3 16.0 33.7 30.3 11.7 8.2 18.1 22.1 21.4 7.2 13.5 8.1 16.5 3.6 11.0 13.0 20.8 13.1 11.4 27.9 54.6 62.2 14.3 16.1 10.3 13.5 22.3 15.3 18.0 NUTF2 "NTF2, PP15" ENSG00000102898 "Nuclear transport factor 2" P61970 16 67846923-67872567 "Plasma proteins, Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 336.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040915, HPA040956" Supported NA NA 2300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA040915: AB_10794073, HPA040956: AB_10796233" "unprognostic (1.74e-1)" "unprognostic (1.43e-1)" "unprognostic (1.59e-1)" "unprognostic (4.41e-3)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.08e-3)" "unprognostic (1.56e-3)" "unprognostic (2.25e-1)" "unprognostic (2.33e-2)" "unprognostic (5.17e-3)" "unprognostic (9.80e-2)" "prognostic unfavorable (2.58e-4)" "unprognostic (1.79e-1)" "unprognostic (1.60e-1)" "unprognostic (9.73e-2)" "unprognostic (1.45e-1)" 57.1 53.7 86.4 36.5 86.6 42.0 49.8 88.8 93.4 47.4 75.3 57.9 27.4 60.7 49.4 53.7 47.9 26.6 74.7 88.4 96.6 50.8 51.5 49.9 47.8 96.2 99.6 42.4 56.9 41.6 43.0 49.8 99.2 44.6 42.6 17.2 40.5 32.5 93.4 58.7 42.8 58.0 90.7 41.4 45.9 56.6 88.3 57.4 39.3 79.2 53.3 57.9 45.2 91.7 149.0 174.8 186.9 212.2 92.8 94.1 249.9 118.8 102.8 165.4 134.1 222.3 152.5 169.2 107.7 161.3 95.9 130.3 235.4 176.2 179.3 65.9 225.5 114.2 73.6 357.5 124.0 161.6 83.1 123.4 114.1 152.9 190.7 91.0 175.5 127.7 164.2 59.1 173.6 301.8 257.3 311.1 318.9 152.4 117.6 228.2 121.5 254.2 218.9 128.5 169.6 164.4 266.4 109.5 93.6 174.5 161.0 137.3 147.4 140.3 168.3 104.2 144.0 94.8 131.0 367.5 92.9 113.0 147.8 47.8 64.0 27.4 61.0 95.7 70.1 52.7 64.9 60.3 81.5 51.8 48.8 55.9 17.9 71.9 88.3 78.7 72.8 101.8 86.4 86.6 88.8 93.4 88.4 96.6 96.2 99.6 99.2 90.7 88.3 91.7 67.6 57.7 20.2 4.9 58.6 68.2 79.5 136.5 64.9 15.9 62.8 53.7 38.7 27.1 58.5 49.7 2.1 208.2 62.4 66.2 137.0 196.5 9.9 71.4 66.1 71.9 98.3 126.4 6.9 105.1 336.1 57.6 60.6 52.7 39.3 65.1 28.2 22.5 149.4 20.2 7.4 69.1 89.5 32.4 83.6 20.8 33.2 75.2 58.7 4.7 130.2 26.5 69.0 4.0 8.3 198.8 93.3 42.9 86.2 166.0 96.5 124.1 53.7 7.6 13.1 48.5 187.5 54.6 82.0 88.7 87.7 183.5 62.9 62.1 95.6 114.5 OLA1 "GTPBP9, PTD004" ENSG00000138430 "Obg like ATPase 1" Q9NTK5 2 174072447-174248599 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035790, HPA041443" Approved Enhanced Cytosol NA NA 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA035790: AB_10601977, HPA041443: AB_2677483" "unprognostic (3.30e-1)" "unprognostic (1.06e-1)" "unprognostic (2.23e-2)" "unprognostic (2.85e-3)" "unprognostic (1.20e-1)" "unprognostic (3.08e-3)" "prognostic unfavorable (9.73e-8)" "unprognostic (6.51e-3)" "unprognostic (7.66e-2)" "unprognostic (1.09e-2)" "unprognostic (3.50e-3)" "unprognostic (1.63e-1)" "unprognostic (1.13e-3)" "unprognostic (4.32e-2)" "unprognostic (2.51e-2)" "unprognostic (2.62e-2)" "unprognostic (9.75e-2)" 42.2 44.3 39.7 38.2 42.7 53.7 57.3 42.5 48.9 34.3 30.0 48.0 50.1 34.7 38.8 58.1 38.0 35.1 57.4 44.5 43.8 56.4 43.0 23.5 47.9 38.0 36.6 31.1 56.3 44.1 27.4 42.0 40.1 41.1 52.7 42.5 36.3 33.6 105.6 52.0 45.7 37.0 38.0 24.6 35.2 48.8 40.7 58.3 59.7 93.1 53.3 48.3 31.0 39.1 181.4 84.1 134.9 225.5 70.1 152.2 243.0 142.1 142.8 194.2 147.1 200.9 104.4 246.5 138.9 114.5 143.9 139.9 165.3 164.6 227.3 113.7 142.5 231.3 76.4 209.9 135.3 264.3 90.2 134.8 200.6 206.3 217.4 177.4 174.5 88.0 256.8 82.3 170.3 116.6 241.4 272.9 159.1 193.9 273.0 180.4 217.8 170.7 245.1 192.0 218.3 124.7 96.8 141.6 206.2 142.2 101.2 220.6 127.5 127.1 161.4 128.5 210.8 76.2 207.3 190.5 124.6 180.0 115.4 18.1 24.9 7.4 16.2 24.2 23.4 17.9 18.6 20.8 37.1 16.4 21.5 21.2 2.1 26.1 20.0 22.5 25.3 22.7 39.7 42.7 42.5 48.9 44.5 43.8 38.0 36.6 40.1 38.0 40.7 39.1 43.2 35.3 33.0 57.5 49.0 62.7 73.5 92.4 76.8 47.3 86.0 83.8 68.3 47.1 57.0 31.3 35.5 153.7 47.7 44.6 103.7 145.1 267.8 37.1 55.2 47.8 70.7 92.5 132.6 105.3 112.8 53.0 60.1 43.1 41.2 73.3 29.3 25.8 97.3 33.7 129.8 79.6 65.1 59.6 54.4 99.5 40.4 55.9 32.0 65.6 83.1 60.3 52.5 101.6 101.8 112.8 51.8 51.1 56.3 84.2 78.4 141.7 36.1 35.9 26.3 69.7 92.3 104.8 35.9 113.7 64.1 105.9 55.9 94.6 107.6 79.3 OSBP OSBP1 ENSG00000110048 "Oxysterol binding protein" P22059 11 59574398-59615774 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039227, HPA043625" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 70000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039227: AB_2676401, HPA043625: AB_2678587" "unprognostic (3.09e-2)" "unprognostic (3.76e-2)" "prognostic favorable (2.08e-5)" "unprognostic (7.80e-3)" "unprognostic (7.32e-2)" "unprognostic (2.79e-2)" "unprognostic (2.13e-1)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (7.42e-2)" "unprognostic (1.42e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.08e-7)" "unprognostic (1.25e-1)" "unprognostic (9.00e-2)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" 19.6 41.7 14.1 15.5 15.2 27.2 27.4 15.3 18.9 24.7 18.4 26.8 29.4 20.0 31.6 19.6 22.4 19.5 25.5 15.0 15.6 42.8 57.6 18.5 17.8 15.4 16.7 22.4 37.3 44.9 16.1 22.9 16.7 25.9 28.3 15.9 30.1 27.0 57.7 26.6 25.5 21.2 14.0 15.6 27.8 18.0 15.7 24.0 32.3 43.8 23.7 19.6 17.1 15.1 40.9 33.6 24.7 33.2 56.5 52.4 26.8 32.9 42.3 38.4 34.4 38.1 40.2 41.1 42.7 37.9 47.2 41.4 45.4 43.5 43.0 40.0 20.9 28.1 25.1 25.8 60.2 36.2 52.9 40.4 52.8 36.2 94.4 40.0 41.7 38.3 48.6 37.3 34.5 19.0 34.0 26.2 28.0 59.5 32.7 32.5 39.8 28.6 45.6 47.0 28.5 20.3 38.6 47.7 46.0 33.6 66.9 22.7 45.8 32.7 22.8 49.5 22.3 51.9 45.2 41.4 37.0 25.6 26.8 1.7 1.6 1.5 2.8 1.4 2.6 2.2 2.9 2.3 1.6 1.6 2.6 2.1 1.5 2.2 1.3 4.0 1.3 1.1 14.1 15.2 15.3 18.9 15.0 15.6 15.4 16.7 16.7 14.0 15.7 15.1 29.2 25.6 9.0 14.7 18.9 39.6 16.4 13.7 29.6 23.8 38.0 27.1 34.1 32.9 19.0 27.6 22.9 14.2 31.1 34.0 7.9 14.0 8.8 37.9 52.7 21.8 30.0 10.5 25.6 18.6 14.7 21.1 22.4 43.8 27.9 21.8 15.4 67.1 16.0 26.9 22.9 40.0 8.2 12.9 16.9 14.5 15.8 17.9 14.2 12.2 9.6 15.7 18.6 18.1 23.3 20.2 20.5 19.9 32.2 31.2 34.6 21.0 27.8 21.7 6.6 28.4 19.3 25.1 14.5 27.0 47.3 30.8 20.0 43.5 28.4 26.4 OSR1 ODD ENSG00000143867 "Odd-skipped related transcription factor 1" Q8TAX0 2 19351485-19358623 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 81.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 35.8;Leydig cells: 133.6;Peritubular cells: 45.9;Smooth muscle cells: 21.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.9" "Region enhanced" "Detected in some" "thalamus: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 11 "U-2197: 101.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015525 Uncertain NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA015525: AB_1854822" "unprognostic (1.71e-3)" "unprognostic (1.23e-1)" "unprognostic (6.85e-4)" "unprognostic (1.42e-1)" "unprognostic (1.39e-1)" "unprognostic (1.45e-2)" "unprognostic (8.47e-4)" "unprognostic (2.79e-1)" "unprognostic (1.91e-1)" "unprognostic (6.87e-2)" "unprognostic (3.56e-2)" "unprognostic (1.03e-1)" "unprognostic (2.21e-3)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (1.62e-1)" 38.6 2.4 0.4 3.5 0.8 0.0 22.4 0.3 1.7 16.7 1.8 23.1 1.4 10.3 0.3 3.6 8.1 5.9 13.4 1.6 0.0 1.5 0.5 17.0 0.5 0.3 0.1 6.1 2.8 0.2 2.7 3.3 0.2 13.9 2.0 0.0 31.5 3.7 3.0 10.8 11.1 11.3 0.2 0.1 9.7 5.4 3.4 0.6 10.2 3.5 0.1 81.4 12.3 0.0 0.0 2.4 0.1 4.7 3.2 9.2 0.0 6.0 2.8 5.6 2.8 0.0 0.1 0.0 0.0 8.5 2.7 0.0 3.0 1.4 1.4 0.0 0.2 0.0 0.1 3.5 4.0 0.0 0.2 4.6 0.0 5.2 6.9 4.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.1 0.0 3.6 5.0 0.0 0.2 0.0 0.6 1.9 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 1.3 0.4 101.8 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.3 1.7 1.6 0.0 0.3 0.1 0.2 0.2 3.4 0.0 1.2 0.0 0.5 0.0 0.0 4.7 1.0 1.7 0.6 0.0 1.0 6.1 7.2 0.0 1.1 3.7 0.0 0.5 0.1 0.1 0.0 1.3 0.7 0.0 0.7 0.5 0.0 0.0 0.1 0.0 0.4 35.8 0.0 0.1 1.3 1.2 0.0 0.0 0.9 0.0 0.0 0.3 4.1 0.0 4.9 3.8 133.6 0.3 3.6 2.8 0.0 0.0 0.0 0.0 0.1 0.4 0.1 45.9 0.0 0.4 0.0 2.9 0.3 0.0 0.0 1.3 21.4 0.4 0.1 0.3 4.1 0.4 0.7 0.8 0.2 1.1 PAFAH1B3 ENSG00000079462 "Platelet activating factor acetylhydrolase 1b catalytic subunit 3" Q15102 19 42297033-42303546 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 188.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035639 Uncertain Approved "Intermediate filaments" NA NA 290000 "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Intermediate filaments" "HPA035639: AB_10670163" "unprognostic (3.19e-1)" "unprognostic (5.38e-3)" "unprognostic (1.13e-1)" "unprognostic (5.99e-2)" "unprognostic (1.83e-1)" "unprognostic (2.09e-2)" "prognostic unfavorable (8.74e-4)" "unprognostic (1.73e-1)" "unprognostic (2.67e-1)" "unprognostic (6.36e-2)" "unprognostic (2.37e-1)" "unprognostic (7.67e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (2.68e-1)" "unprognostic (3.21e-2)" "unprognostic (4.56e-2)" "unprognostic (6.80e-3)" 8.3 23.5 34.7 12.4 35.4 27.9 13.7 36.5 44.1 18.9 31.3 16.8 12.4 13.8 12.9 28.1 14.8 10.8 4.6 35.1 39.9 21.8 7.9 9.2 17.0 32.2 33.1 18.3 18.1 13.8 21.2 5.9 34.4 15.2 12.1 13.0 17.0 6.3 13.5 13.6 14.7 7.5 32.0 16.0 15.9 23.7 42.9 37.6 9.3 5.2 18.3 14.1 16.6 32.5 111.9 200.2 127.5 135.8 2.6 6.7 38.1 27.9 39.2 91.9 94.4 67.7 94.7 70.0 34.8 35.0 63.7 37.1 58.9 75.2 38.3 105.7 77.0 85.8 52.7 91.8 19.3 54.4 90.3 19.9 33.9 56.5 26.3 50.7 41.3 152.5 58.5 81.9 67.9 162.5 124.2 42.4 70.3 138.3 0.2 90.0 47.9 62.0 76.4 117.7 144.8 109.9 44.6 89.4 47.0 40.4 111.4 62.1 22.3 74.8 98.5 6.7 77.3 38.0 84.9 60.6 41.3 87.4 65.8 23.2 27.5 15.7 23.4 22.3 31.2 38.3 32.8 26.7 51.1 48.2 43.3 30.6 3.4 18.2 12.0 27.8 58.1 21.0 34.7 35.4 36.5 44.1 35.1 39.9 32.2 33.1 34.4 32.0 42.9 32.5 18.8 16.0 11.2 3.6 26.1 28.2 45.7 82.7 46.1 26.5 67.9 83.2 2.3 30.0 41.6 33.1 14.6 38.6 13.2 39.1 80.3 112.9 16.7 30.4 12.4 24.4 58.9 53.0 3.0 55.3 44.9 21.7 38.7 33.1 27.9 71.4 17.9 10.3 62.7 11.8 5.4 54.0 87.5 28.2 33.5 27.0 13.7 21.8 46.2 1.0 18.2 33.7 11.3 3.0 3.6 81.5 36.1 9.1 37.3 31.0 30.9 63.7 35.0 19.8 0.0 3.6 52.6 5.6 188.8 59.0 17.8 13.5 24.6 46.2 74.3 58.9 PAPOLA PAP ENSG00000090060 "Poly(A) polymerase alpha" P51003 14 96501433-96567111 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1036.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001788 Supported Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA001788: AB_1079564" "unprognostic (3.18e-1)" "unprognostic (1.30e-1)" "unprognostic (9.69e-2)" "unprognostic (7.26e-2)" "unprognostic (9.10e-2)" "unprognostic (5.10e-3)" "prognostic unfavorable (2.41e-5)" "unprognostic (2.12e-2)" "unprognostic (2.82e-2)" "unprognostic (1.38e-3)" "unprognostic (3.13e-1)" "unprognostic (1.22e-3)" "unprognostic (3.37e-1)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (1.08e-2)" "unprognostic (4.05e-1)" 52.6 60.5 62.7 66.6 65.1 96.9 62.7 71.7 87.4 61.7 70.1 70.5 57.1 68.5 72.5 59.6 57.9 56.1 61.0 59.9 64.4 60.7 81.6 50.0 77.8 63.0 61.7 76.1 71.6 73.2 53.0 85.3 64.3 54.2 71.8 92.4 63.8 54.0 46.7 57.9 67.6 61.6 62.8 69.3 65.9 75.8 62.1 93.0 68.9 56.4 82.8 66.4 53.5 80.7 126.6 119.4 150.5 152.6 107.2 119.4 331.6 112.9 120.4 132.1 125.8 132.9 125.6 170.9 125.3 134.1 115.2 104.4 50.1 156.9 235.0 141.1 81.1 131.9 88.9 138.5 110.6 166.2 133.4 110.6 134.1 148.0 131.1 127.8 150.5 79.5 128.2 146.5 128.9 184.6 140.5 91.1 102.9 205.0 135.3 146.7 183.5 98.7 132.0 192.7 154.0 102.0 151.4 115.8 111.6 167.9 165.3 158.3 119.0 91.3 72.6 104.1 140.7 114.3 186.7 138.6 144.5 137.5 158.9 73.5 32.0 56.1 23.8 39.3 29.0 38.9 30.2 34.2 38.8 42.7 35.3 33.9 41.3 41.3 37.7 25.1 32.7 36.6 62.7 65.1 71.7 87.4 59.9 64.4 63.0 61.7 64.3 62.8 62.1 80.7 126.3 80.1 122.4 64.6 171.4 229.7 406.3 196.6 126.9 78.2 140.0 101.6 157.2 88.6 160.1 84.6 95.9 346.2 139.6 124.1 183.9 121.4 634.7 326.1 145.4 150.7 117.2 126.8 87.9 137.0 440.7 129.9 95.3 371.7 136.4 113.8 85.6 112.3 155.6 63.9 111.5 154.9 168.9 141.3 239.4 275.3 96.3 153.2 168.9 104.9 171.8 93.4 135.9 105.1 115.2 129.6 118.9 80.5 197.4 373.0 122.5 136.5 253.1 107.2 105.2 131.6 185.0 256.8 203.0 146.0 247.6 1036.0 167.8 131.2 166.1 540.3 PAPOLB PAPT ENSG00000218823 "Poly(A) polymerase beta" Q9NRJ5 7 4857738-4862030 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "testis: 29.9" "Cell type enhanced" "Detected in some" "Early spermatids: 94.8;Late spermatids: 89.7;Smooth muscle cells: 18.5;Spermatocytes: 37.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047285 Approved Nucleoplasm NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA047285: " "unprognostic (7.58e-2)" "unprognostic (1.25e-1)" "unprognostic (1.68e-2)" "unprognostic (1.78e-1)" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 29.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.4 1.2 0.2 0.0 0.9 0.2 0.1 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.8 0.2 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 89.7 2.5 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.2 0.8 0.0 0.7 18.5 37.4 4.0 0.0 0.9 0.3 0.1 0.1 0.0 0.3 PARL "PRO2207, PSARL, PSARL1, RHBDS1" ENSG00000175193 "Presenilin associated rhomboid like" Q9H300 3 183829271-183884933 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA019545 Approved Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA019545: AB_1855796" "unprognostic (2.10e-1)" "unprognostic (1.53e-3)" "unprognostic (5.88e-2)" "unprognostic (1.17e-2)" "unprognostic (5.76e-2)" "unprognostic (9.55e-2)" "unprognostic (3.17e-3)" "unprognostic (8.97e-2)" "unprognostic (1.81e-1)" "unprognostic (3.62e-3)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (4.28e-2)" "unprognostic (5.49e-2)" "unprognostic (2.58e-1)" "unprognostic (1.73e-1)" "prognostic favorable (9.11e-5)" 38.4 35.8 46.5 26.6 48.2 33.8 40.3 47.4 66.2 33.8 50.7 47.7 29.2 31.9 57.7 36.7 30.2 19.7 54.1 46.6 48.2 39.6 45.0 28.4 32.0 47.7 48.7 31.7 49.9 39.7 32.0 25.5 47.4 37.1 41.9 32.7 40.5 30.3 54.9 37.1 34.7 29.7 47.2 36.2 42.6 26.7 47.6 34.5 31.4 51.6 33.8 38.9 31.5 48.4 115.1 55.6 39.7 33.0 38.8 42.1 80.2 39.2 59.4 80.5 65.0 172.0 59.0 47.8 90.0 56.7 73.5 49.2 64.1 68.0 90.0 71.6 76.1 73.9 35.5 96.9 57.3 73.9 61.6 60.0 85.4 58.0 70.7 38.5 59.0 82.4 42.6 45.0 69.2 131.0 148.3 194.3 105.5 100.6 53.3 64.7 72.8 92.0 79.0 97.6 37.9 52.0 47.6 162.9 107.8 48.1 159.2 143.5 31.8 29.3 63.0 60.9 108.2 89.2 65.7 116.0 56.6 75.1 35.5 97.5 143.1 133.4 51.3 107.8 60.9 62.4 57.3 59.9 132.4 59.1 68.7 54.2 41.3 67.1 83.3 79.7 73.7 116.1 46.5 48.2 47.4 66.2 46.6 48.2 47.7 48.7 47.4 47.2 47.6 48.4 30.3 22.4 19.7 17.9 37.6 30.3 54.9 93.5 26.7 35.9 31.8 31.5 41.2 35.8 44.5 31.3 31.3 58.9 38.4 24.4 117.4 63.9 24.0 15.2 18.3 30.2 33.7 23.3 23.4 84.7 49.0 35.1 28.1 13.7 69.8 33.1 33.2 30.4 77.7 33.7 24.1 42.0 77.3 56.2 55.7 9.7 28.9 57.5 42.7 33.7 79.3 55.9 50.4 17.1 28.0 60.3 35.1 27.1 42.3 55.4 47.3 86.0 30.5 51.1 6.6 44.8 96.6 47.8 47.4 40.2 30.0 42.1 40.9 49.0 49.2 58.8 PARP2 "ADPRTL2, ARTD2" ENSG00000129484 "Poly(ADP-ribose) polymerase 2" Q9UGN5 14 20343615-20357904 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052003 Approved Supported Nucleoplasm,Nucleoli NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA052003: AB_2681689" "unprognostic (3.93e-1)" "unprognostic (7.92e-2)" "unprognostic (4.12e-1)" "unprognostic (1.24e-1)" "unprognostic (3.40e-2)" "unprognostic (7.30e-2)" "prognostic unfavorable (6.48e-4)" "unprognostic (1.97e-2)" "unprognostic (4.43e-2)" "unprognostic (9.35e-3)" "unprognostic (1.44e-2)" "unprognostic (1.42e-2)" "unprognostic (3.37e-3)" "unprognostic (2.83e-1)" "unprognostic (9.19e-2)" "unprognostic (1.91e-1)" "unprognostic (2.89e-2)" 17.7 21.1 21.1 10.7 22.0 26.8 17.5 21.4 31.4 18.1 16.4 19.3 12.8 20.9 17.8 14.6 17.5 10.0 17.1 22.5 21.0 15.5 17.2 13.5 14.5 19.5 18.9 22.9 17.9 11.1 21.0 12.9 19.8 13.9 14.0 26.4 14.2 13.4 32.4 19.2 14.2 15.8 19.0 16.5 16.3 23.8 19.8 11.9 16.7 27.1 17.9 13.8 15.3 22.1 55.5 39.5 59.7 45.3 19.4 18.4 43.4 60.2 32.5 74.8 91.8 36.8 51.3 40.4 26.5 19.0 64.8 50.1 78.3 27.5 87.8 32.4 38.3 37.2 46.6 63.3 17.3 77.9 20.4 12.5 23.0 45.5 51.1 20.5 38.5 48.0 39.2 53.4 52.3 33.5 40.1 33.0 33.0 62.8 60.0 49.7 79.7 26.5 30.0 28.2 41.3 28.3 65.3 36.8 17.9 37.4 34.2 25.8 26.6 45.3 68.1 31.5 48.1 49.3 67.7 53.4 19.0 33.3 51.4 1.9 5.0 0.5 8.9 4.8 11.7 6.8 8.4 7.9 5.5 4.1 9.0 8.6 0.1 7.6 2.6 5.6 5.3 4.8 21.1 22.0 21.4 31.4 22.5 21.0 19.5 18.9 19.8 19.0 19.8 22.1 12.1 25.6 6.5 7.2 9.5 6.5 10.5 16.1 18.8 29.2 7.4 10.0 14.0 5.7 19.9 7.3 12.5 25.8 10.2 4.5 7.9 12.8 9.3 9.9 13.3 11.0 4.8 30.3 17.6 8.7 22.2 11.6 7.7 11.3 8.2 18.4 6.8 10.1 11.9 30.3 15.5 5.0 14.2 4.6 5.1 9.8 11.5 6.6 8.8 9.4 4.2 20.7 6.2 6.0 9.3 10.1 4.5 17.0 19.1 4.5 5.3 7.4 28.0 23.2 6.6 9.8 18.5 20.9 41.5 11.3 4.8 14.9 6.2 16.7 7.4 7.0 PBRM1 "BAF180, PB1" ENSG00000163939 "Polybromo 1" Q86U86 3 52545352-52685917 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015629, HPA059373" Uncertain Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA015629: AB_1855012, HPA059373: AB_2683994" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.91e-2)" "unprognostic (2.00e-1)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "unprognostic (1.02e-2)" "unprognostic (9.54e-2)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (1.99e-2)" "unprognostic (4.32e-2)" "unprognostic (2.89e-3)" "unprognostic (3.06e-1)" "unprognostic (1.96e-1)" "unprognostic (1.53e-2)" "unprognostic (1.06e-1)" 21.4 12.9 6.4 20.8 11.0 24.6 16.6 18.5 8.9 21.1 13.2 17.9 15.4 22.1 16.4 22.5 19.4 16.9 18.5 6.0 11.9 11.2 18.2 17.6 22.1 10.7 9.9 29.4 12.0 14.3 8.7 20.9 11.8 18.6 18.5 20.2 13.1 17.4 15.5 17.3 14.2 25.4 8.6 18.9 16.0 14.1 10.3 42.0 26.7 22.8 22.0 20.0 12.0 19.8 32.5 20.5 71.9 35.4 34.7 35.0 50.4 44.5 29.9 49.5 43.0 23.3 21.5 78.7 6.2 51.8 40.8 21.8 63.1 33.1 59.6 85.5 34.6 74.6 38.1 18.1 49.6 62.7 54.6 33.2 37.3 55.4 35.4 38.9 48.4 60.6 43.7 41.7 50.3 11.0 103.9 18.8 43.8 22.0 34.4 53.8 45.1 40.1 20.4 62.5 48.7 53.8 52.7 12.4 41.6 43.4 23.4 35.7 56.5 46.1 34.8 40.1 54.4 30.0 51.3 73.6 28.5 49.8 46.9 9.0 4.0 9.9 3.6 2.6 3.8 2.9 3.6 4.0 4.0 5.3 5.7 3.6 2.3 3.6 8.0 8.7 3.9 1.6 6.4 11.0 18.5 8.9 6.0 11.9 10.7 9.9 11.8 8.6 10.3 19.8 49.1 41.7 61.3 95.3 44.0 40.5 35.8 28.3 43.9 45.6 40.7 30.4 61.7 30.0 39.8 23.9 47.9 36.0 67.7 36.8 19.6 37.7 39.1 61.4 54.5 47.7 35.2 82.9 76.4 46.2 36.9 39.8 42.8 46.8 29.1 61.9 33.5 47.9 53.0 30.3 84.5 35.3 28.5 61.7 47.7 17.1 34.2 65.6 48.0 80.6 67.6 29.1 49.4 87.9 135.5 49.7 29.2 58.3 76.9 37.5 18.7 18.4 58.2 44.3 26.3 54.3 69.2 48.6 35.8 43.7 51.6 50.9 50.4 45.8 39.8 37.0 PCBP1 "hnRNP-E1, hnRNP-X, HNRPE1, HNRPX" ENSG00000169564 "Poly(rC) binding protein 1" Q15365 2 70087477-70089203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Viral RNA replication" "DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037113, HPA043803, HPA068497" Approved Enhanced "Nuclear speckles,Cytoplasmic bodies" No No 1600000 "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Cytoplasmic bodies" "CAB037113: AB_1840915, HPA043803: AB_2678676, HPA068497: AB_2685996" "unprognostic (1.63e-1)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (7.08e-2)" "unprognostic (5.37e-1)" "unprognostic (1.63e-2)" "unprognostic (8.33e-2)" "unprognostic (9.94e-3)" "unprognostic (2.01e-1)" "unprognostic (2.70e-1)" "unprognostic (6.65e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.71e-5)" "unprognostic (3.85e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-1)" "unprognostic (5.90e-2)" 278.3 276.3 145.5 199.8 155.0 390.0 240.4 168.5 203.5 209.3 159.1 259.9 172.8 253.9 142.6 278.4 193.8 134.9 223.2 142.1 155.6 218.1 304.3 233.6 227.1 163.7 146.9 186.0 249.9 174.6 140.2 194.8 159.2 143.9 125.8 90.5 185.0 139.5 782.3 216.6 203.1 172.4 163.8 241.3 214.5 95.2 150.4 301.0 170.8 308.3 209.6 233.8 206.0 190.9 384.9 387.5 327.1 257.5 345.1 262.4 525.9 280.5 257.2 272.0 227.0 453.0 250.6 522.9 140.9 320.7 293.7 334.7 388.4 408.6 276.5 376.2 299.9 419.2 219.5 701.3 388.0 350.8 385.8 230.3 261.6 224.5 310.5 203.4 350.7 138.9 437.2 375.6 346.2 475.7 454.7 524.7 331.5 361.1 253.2 362.9 358.0 527.1 375.5 389.6 309.7 249.1 230.3 465.8 342.1 229.8 277.6 314.2 325.1 253.5 317.6 217.6 359.4 495.7 551.2 531.7 268.6 480.4 319.5 42.6 89.7 141.5 80.3 92.5 73.8 41.1 62.1 69.3 82.9 36.4 62.8 71.2 138.2 95.4 80.5 58.9 81.7 100.5 145.5 155.0 168.5 203.5 142.1 155.6 163.7 146.9 159.2 163.8 150.4 190.9 241.0 153.8 132.7 27.4 312.7 484.0 296.0 192.1 196.9 64.9 270.8 212.6 0.6 208.8 134.5 196.8 22.9 372.4 208.7 401.7 272.0 196.0 34.4 187.6 220.8 242.8 178.6 485.3 19.1 199.2 470.1 196.9 227.9 284.8 114.2 129.6 227.0 392.7 385.7 58.9 18.0 239.8 138.4 509.2 795.9 34.4 186.1 382.4 300.6 30.0 422.9 122.3 347.1 14.1 49.1 211.7 311.7 186.5 357.1 278.5 338.4 481.0 128.6 56.1 170.9 222.9 241.9 131.0 65.5 267.0 545.8 703.4 291.2 148.4 232.9 366.6 PCBP2 "hnRNP-E2, HNRNPE2, HNRPE2" ENSG00000197111 "Poly(rC) binding protein 2" Q15366 12 53452102-53481162 "Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Viral RNA replication" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038356, HPA073145" Approved Supported Nucleoplasm,Cytosol NA NA 970000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA038356: AB_10697248, HPA073145: " "unprognostic (1.44e-1)" "unprognostic (2.08e-1)" "unprognostic (9.89e-2)" "unprognostic (2.92e-3)" "unprognostic (4.34e-3)" "unprognostic (2.69e-2)" "prognostic unfavorable (1.82e-5)" "unprognostic (2.52e-1)" "unprognostic (2.05e-2)" "prognostic favorable (8.23e-4)" "unprognostic (3.53e-2)" "unprognostic (2.12e-1)" "unprognostic (2.04e-1)" "unprognostic (9.84e-2)" "unprognostic (3.35e-1)" "unprognostic (1.99e-1)" "unprognostic (8.20e-2)" 467.6 429.4 213.6 263.0 232.5 863.1 396.1 260.1 240.3 385.9 238.8 318.2 334.8 345.0 366.4 314.4 407.8 301.5 340.3 197.9 232.9 534.9 509.0 350.9 380.4 228.2 223.5 507.3 501.5 437.3 220.7 299.7 232.8 265.5 325.5 665.2 322.1 264.5 481.1 416.6 324.5 333.8 227.4 323.8 390.4 363.6 228.8 543.6 414.9 401.7 455.6 313.3 323.5 263.2 527.6 809.2 755.8 614.7 1068.5 809.3 582.3 547.0 722.3 844.6 605.4 951.9 760.5 916.9 518.6 796.7 398.6 501.2 830.1 720.1 830.0 579.1 617.4 917.3 597.0 946.0 1071.1 922.5 592.1 937.8 593.9 719.6 1147.1 1451.3 819.3 583.5 810.8 1621.9 762.9 1444.3 856.8 1030.1 975.1 447.8 559.7 690.0 686.4 1098.4 667.5 814.6 742.4 655.6 736.2 656.2 553.9 767.2 918.2 791.8 615.9 443.9 614.0 412.7 561.7 908.2 666.0 840.7 523.9 572.6 494.4 19.1 34.5 25.9 27.7 34.0 44.6 38.1 42.3 35.7 41.6 34.3 48.1 41.8 30.8 23.9 33.3 57.2 52.3 30.1 213.6 232.5 260.1 240.3 197.9 232.9 228.2 223.5 232.8 227.4 228.8 263.2 306.1 115.4 179.2 64.9 433.6 390.7 302.9 352.6 569.1 88.0 361.5 389.9 73.7 253.1 193.0 296.1 110.5 329.2 313.6 242.9 493.1 233.0 68.3 264.2 289.3 285.1 206.5 525.1 54.6 240.0 365.1 285.8 326.2 298.1 155.0 360.3 283.4 302.2 368.2 102.6 58.1 279.1 223.8 437.6 473.8 65.6 309.1 376.0 233.1 74.0 476.5 152.9 292.5 58.8 101.4 250.8 266.5 229.0 483.8 256.3 446.8 714.4 159.5 188.3 190.7 346.6 435.1 292.8 183.4 511.3 382.3 443.3 341.6 240.4 325.7 345.0 PCGF1 "MGC10882, NSPC1, RNF68" ENSG00000115289 "Polycomb group ring finger 1" Q9BSM1 2 74505043-74507695 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA011356, HPA069156" Supported Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA011356: AB_1855063, HPA069156: AB_2686095" "unprognostic (2.41e-1)" "unprognostic (5.97e-2)" "unprognostic (1.11e-3)" "unprognostic (2.71e-2)" "unprognostic (4.25e-2)" "unprognostic (2.73e-2)" "unprognostic (2.32e-2)" "unprognostic (4.18e-3)" "unprognostic (2.26e-1)" "unprognostic (2.14e-1)" "unprognostic (1.57e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (1.69e-4)" "unprognostic (1.00e-1)" "unprognostic (5.09e-2)" "unprognostic (1.21e-1)" "unprognostic (2.13e-1)" 9.9 10.4 13.7 8.6 14.5 17.8 15.2 14.6 17.3 12.8 13.0 11.5 11.2 12.5 14.4 9.7 14.4 10.0 12.3 14.1 13.9 10.9 13.0 12.3 14.1 13.9 13.8 14.8 11.0 17.6 2.3 11.4 14.7 9.3 12.3 18.1 11.0 8.8 12.1 14.8 10.8 11.2 13.7 8.5 11.7 11.0 14.5 14.4 14.2 17.6 14.7 10.7 2.1 15.1 18.9 11.6 12.3 19.0 15.4 19.0 19.0 17.8 23.8 16.2 10.9 25.5 12.8 16.9 7.6 16.5 38.0 11.4 20.7 23.5 14.6 16.3 24.7 12.0 15.7 25.6 24.9 31.7 16.5 25.5 33.3 10.5 57.4 26.0 12.8 21.8 25.0 23.0 17.8 27.8 22.6 42.0 16.3 23.5 12.3 18.0 27.3 14.1 24.8 21.0 14.0 27.8 13.8 27.1 30.1 12.1 10.1 21.4 11.7 26.2 17.5 14.5 24.1 12.5 9.7 18.3 22.1 22.6 16.3 11.1 24.2 10.4 15.5 20.1 18.3 18.1 20.7 19.8 26.9 17.9 16.3 16.8 8.7 14.4 23.3 13.1 24.2 14.2 13.7 14.5 14.6 17.3 14.1 13.9 13.9 13.8 14.7 13.7 14.5 15.1 7.0 3.2 1.8 2.3 8.7 12.5 9.0 23.8 31.3 5.0 10.5 10.9 3.5 12.8 10.6 3.7 4.2 12.2 6.5 9.5 31.3 11.0 19.0 11.3 11.5 8.5 1.2 10.3 1.7 10.4 19.5 13.1 6.1 10.4 10.2 2.9 7.1 6.2 13.6 5.0 1.6 12.8 18.3 9.9 14.0 4.9 7.8 10.8 7.2 0.0 15.0 6.7 19.6 0.5 2.3 11.3 15.9 4.9 11.4 9.4 14.2 17.5 9.5 9.5 6.6 10.4 14.0 19.3 8.0 24.3 18.9 18.3 9.6 5.0 9.4 8.5 PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 491.6;Fibroblasts: 439.9;Leydig cells: 140.5;Smooth muscle cells: 442.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 879.0;BJ hTERT+: 663.0;fHDF/TERT166: 404.5;HSkMC: 973.2;SH-SY5Y: 689.9;U-2197: 1213.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" 101.5 45.5 2.4 51.5 3.8 0.6 72.6 3.5 10.2 162.8 4.6 30.5 7.8 81.7 11.0 26.9 80.6 112.5 110.8 2.3 2.5 21.9 59.7 72.4 41.3 3.0 2.4 47.7 20.6 10.3 31.2 59.5 2.9 45.5 16.7 0.2 24.9 33.5 16.9 45.0 21.6 59.9 3.1 13.8 22.9 13.7 3.6 10.5 49.1 32.7 17.4 86.4 86.7 2.5 0.2 0.5 2.2 3.0 321.5 879.0 2.4 355.5 663.0 161.1 142.7 14.5 0.8 1.1 1.2 404.5 0.5 0.2 0.0 1.2 15.9 2.5 2.5 0.3 6.1 19.8 82.1 0.1 3.5 973.2 0.3 86.3 0.6 0.4 0.1 1.7 8.3 2.0 0.7 2.1 0.6 3.3 72.2 0.0 4.2 1.0 1.5 0.8 0.4 0.6 1.1 689.9 0.2 2.4 1.6 8.2 2.0 0.0 3.5 391.8 107.6 1213.4 0.2 0.4 0.5 0.1 136.6 1.2 68.2 0.0 0.0 0.4 0.1 0.3 0.3 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.1 0.0 2.4 3.8 3.5 10.2 2.3 2.5 3.0 2.4 2.9 3.1 3.6 2.5 33.6 9.6 2.8 2.3 2.5 40.0 3.3 4.2 6.8 4.3 6.6 11.3 16.3 4.3 5.5 5.5 0.0 13.3 4.5 0.8 27.4 6.4 14.8 15.1 491.6 17.2 1.8 5.7 0.5 5.1 11.2 439.9 7.1 11.0 1.3 0.7 33.9 44.8 20.8 16.8 2.5 0.9 6.1 1.9 53.6 27.6 140.5 5.5 32.0 9.4 0.8 12.1 6.2 1.5 0.2 4.1 1.3 50.4 2.1 2.2 0.1 2.5 6.8 2.0 32.9 14.2 442.2 32.8 21.0 3.6 33.1 25.2 9.4 22.6 0.7 3.0 PDAP1 "HASPP28, PAP, PAP1" ENSG00000106244 "PDGFA associated protein 1" Q13442 7 99392048-99408597 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021103, HPA050294, HPA060836" Approved Enhanced "Plasma membrane,Cytosol" NA NA 410000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Cytosol "Plasma membrane" "CAB021103: AB_10057973, HPA050294: AB_2681077, HPA060836: AB_2684374" "unprognostic (2.27e-1)" "unprognostic (1.45e-1)" "unprognostic (3.87e-2)" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.67e-4)" "unprognostic (5.77e-2)" "unprognostic (3.50e-1)" "unprognostic (2.65e-2)" "unprognostic (2.63e-1)" "unprognostic (3.35e-2)" "unprognostic (1.45e-2)" "unprognostic (3.51e-2)" "unprognostic (1.79e-1)" "unprognostic (3.49e-1)" "unprognostic (2.97e-2)" 25.7 29.6 35.8 22.6 36.2 23.2 24.4 36.5 39.3 26.2 34.1 32.4 17.9 26.9 17.5 37.2 22.6 11.9 40.2 34.4 36.1 28.5 31.3 24.0 18.9 37.3 37.9 25.7 26.6 22.5 21.9 19.2 37.4 26.0 18.0 22.9 26.2 20.9 105.0 27.9 23.3 21.1 37.6 23.8 26.3 19.7 37.0 25.5 24.3 59.7 22.4 29.3 26.4 36.6 96.9 82.4 54.6 71.0 41.5 43.2 34.7 76.7 44.9 61.6 51.8 83.9 47.4 41.3 67.2 74.7 78.4 50.2 66.3 78.4 60.5 59.8 74.4 43.6 80.8 74.1 60.8 80.1 40.5 45.6 58.5 68.1 110.3 56.3 62.7 67.5 103.0 75.6 61.4 200.3 110.4 111.2 68.7 98.1 88.3 50.5 54.3 73.6 63.6 73.0 54.8 110.6 58.0 92.4 43.4 61.3 41.1 42.5 57.6 83.6 91.4 100.8 123.6 71.4 87.5 91.0 67.7 72.2 89.1 13.4 12.1 12.5 15.4 16.6 13.9 15.7 14.2 11.2 10.2 14.9 9.8 13.2 31.6 28.0 15.6 21.1 20.9 6.6 35.8 36.2 36.5 39.3 34.4 36.1 37.3 37.9 37.4 37.6 37.0 36.6 82.9 86.6 94.7 6.2 73.6 62.2 110.6 104.6 57.5 97.4 84.3 76.6 63.6 72.9 86.7 42.3 33.3 213.1 84.7 101.6 168.3 176.1 60.3 91.3 118.6 99.1 117.9 151.7 10.1 171.0 223.0 87.4 59.7 88.3 72.2 83.4 61.8 80.8 114.9 77.4 11.6 116.5 75.3 38.3 63.3 78.3 83.6 66.1 103.2 5.6 102.1 166.4 119.4 8.0 17.4 177.4 92.2 92.2 102.5 184.3 100.0 134.5 96.8 101.0 52.6 85.6 127.2 132.5 123.0 131.9 65.6 184.4 79.5 115.2 114.0 122.5 PDCD10 "CCM3, TFAR15" ENSG00000114209 "Programmed cell death 10" Q9BUL8 3 167683298-167734939 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Angiogenesis, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027095 Approved NA NA 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA027095: AB_1855101" "unprognostic (3.39e-2)" "unprognostic (2.75e-1)" "unprognostic (4.98e-2)" "prognostic unfavorable (9.34e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.89e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (4.98e-3)" "unprognostic (2.41e-2)" "unprognostic (9.95e-3)" "prognostic unfavorable (5.22e-5)" "unprognostic (3.08e-2)" "prognostic favorable (5.88e-4)" "unprognostic (1.98e-1)" "unprognostic (2.45e-1)" "unprognostic (3.14e-1)" "unprognostic (5.58e-2)" 34.4 30.4 24.0 39.2 27.1 61.7 41.3 28.4 34.3 24.9 22.6 50.9 48.7 27.3 29.1 50.4 24.4 29.5 35.9 25.6 28.0 43.5 36.4 31.4 53.0 26.9 25.6 25.6 25.7 41.5 21.9 44.4 27.3 31.0 48.7 20.3 31.4 24.7 21.8 27.6 43.4 30.3 27.9 33.1 41.3 44.1 25.9 50.9 37.9 29.6 52.6 50.2 32.3 32.2 133.1 49.3 61.6 39.6 56.7 62.1 67.7 78.5 82.7 89.8 89.9 92.3 153.3 107.5 150.0 73.2 156.5 86.0 73.1 91.1 108.0 172.2 52.9 164.8 59.3 61.1 80.3 109.8 93.0 47.9 92.7 56.9 92.6 64.3 73.3 89.1 129.6 105.2 82.1 117.2 88.4 67.7 79.3 119.3 67.9 51.3 46.9 157.9 112.7 53.5 58.9 52.1 75.2 80.8 148.5 76.8 149.0 92.4 70.5 63.5 41.2 68.9 113.5 113.4 170.9 187.6 75.3 114.6 53.2 224.8 81.7 196.5 82.4 107.0 100.1 136.2 111.2 100.2 79.4 136.4 92.0 95.3 175.0 107.1 138.9 73.2 181.9 133.8 24.0 27.1 28.4 34.3 25.6 28.0 26.9 25.6 27.3 27.9 25.9 32.2 103.3 44.8 42.6 18.6 74.8 108.1 91.0 227.1 69.4 20.2 49.1 57.4 71.1 32.9 120.9 33.1 6.2 106.2 76.9 100.1 105.7 101.4 76.0 58.8 48.3 69.8 34.6 123.3 48.0 122.0 112.3 52.9 62.7 61.4 62.7 34.8 45.3 41.5 91.2 20.2 33.8 75.4 120.1 53.8 73.6 33.5 49.7 89.0 49.8 27.2 100.5 52.9 88.6 19.1 49.7 121.7 103.0 39.5 51.2 97.2 72.0 123.5 92.8 24.1 32.9 37.9 128.4 119.5 103.7 66.6 129.0 103.0 77.9 38.9 55.9 122.7 PDCD2L MGC13096 ENSG00000126249 "Programmed cell death 2 like" Q9BRP1 19 34404399-34426168 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 24.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 35.7;Spermatogonia: 42.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052181 Approved Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA052181: AB_2681751" "unprognostic (5.39e-2)" "unprognostic (3.48e-1)" "unprognostic (1.51e-1)" "unprognostic (6.99e-2)" "unprognostic (1.07e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.81e-4)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (8.78e-2)" "unprognostic (1.30e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.75e-1)" "unprognostic (1.72e-1)" "unprognostic (3.00e-2)" "unprognostic (5.98e-2)" 4.2 5.6 5.0 2.7 5.3 3.1 4.1 4.8 5.8 4.3 4.2 5.3 2.6 5.0 2.9 5.3 5.0 2.1 7.5 5.0 5.6 3.5 5.5 2.9 4.7 4.5 4.7 4.4 8.3 2.2 5.8 2.5 4.9 3.4 3.4 1.1 5.5 3.8 24.7 4.7 4.0 3.1 4.7 4.8 6.5 14.4 5.4 2.9 3.1 9.1 4.8 4.8 3.9 5.7 21.6 35.9 4.4 8.7 2.0 4.2 13.8 6.8 4.9 11.1 11.1 33.6 15.1 17.7 28.8 3.9 11.6 7.4 17.4 14.9 11.7 26.1 36.6 17.4 5.7 26.8 14.5 34.0 9.8 5.1 12.9 6.5 21.2 4.6 11.3 28.0 35.1 9.0 9.6 27.3 13.4 12.4 16.0 47.3 34.4 19.2 8.2 25.1 14.1 12.1 25.8 9.2 0.7 21.4 12.5 7.3 9.3 13.9 6.0 7.3 9.0 8.6 23.4 20.1 32.8 31.4 9.1 29.8 6.3 0.0 3.3 0.0 9.1 5.3 12.9 12.7 8.9 9.0 6.8 10.1 13.1 9.9 0.7 12.5 3.4 23.6 11.7 5.7 5.0 5.3 4.8 5.8 5.0 5.6 4.5 4.7 4.9 4.7 5.4 5.7 5.5 3.2 4.8 3.6 7.6 8.2 15.0 7.6 10.2 4.3 4.8 7.4 5.1 5.7 4.8 3.7 2.1 8.1 12.0 1.7 7.9 13.3 27.4 6.3 4.3 4.9 12.1 4.6 4.2 15.3 7.0 5.1 9.2 2.7 4.5 5.6 5.0 5.1 7.5 1.7 4.3 5.0 2.0 3.3 3.7 3.9 5.3 4.1 3.6 2.8 7.1 4.8 9.2 4.0 3.4 13.1 5.0 6.8 8.2 27.6 1.1 10.2 6.1 2.4 0.0 6.1 12.6 35.7 42.9 7.5 10.7 1.8 5.4 8.2 7.7 9.6 PDCD5 "MGC9294, TFAR19" ENSG00000105185 "Programmed cell death 5" O14737 19 32581190-32587453 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018471 Enhanced Approved Nucleoplasm,Cytosol NA NA 47000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "HPA018471: AB_1855108" "unprognostic (1.04e-1)" "unprognostic (2.08e-1)" "unprognostic (9.65e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (2.02e-1)" "unprognostic (8.64e-2)" "unprognostic (3.64e-3)" "unprognostic (2.43e-2)" "unprognostic (6.22e-2)" "unprognostic (8.49e-2)" "unprognostic (3.87e-2)" "unprognostic (1.93e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (6.00e-2)" "unprognostic (3.35e-2)" "unprognostic (1.10e-1)" "unprognostic (9.54e-2)" 95.7 96.1 86.2 73.8 87.0 46.8 82.0 85.4 110.2 73.2 80.8 100.1 65.8 68.8 50.8 109.3 70.9 34.8 170.9 86.7 91.1 97.8 101.2 68.0 58.6 87.1 87.7 71.8 102.4 52.6 95.1 61.2 88.4 64.3 55.7 39.2 70.1 41.9 224.2 60.5 62.0 65.8 85.8 56.8 78.9 144.4 94.6 41.8 60.6 132.2 59.5 91.1 80.3 89.9 499.0 630.0 168.8 163.7 223.8 334.0 190.0 353.2 225.6 295.2 252.2 525.0 188.3 272.6 498.7 177.1 286.3 133.2 213.6 281.7 254.4 493.1 333.6 412.4 303.9 382.8 284.0 587.0 157.3 219.7 253.8 195.9 315.0 145.1 198.8 214.9 381.0 298.8 247.2 332.0 243.6 298.6 164.9 410.5 211.6 238.9 248.8 323.6 231.9 167.6 326.0 178.4 338.1 351.8 283.4 125.2 152.6 294.6 299.4 272.6 291.7 274.2 602.7 270.6 413.0 504.4 302.3 459.8 244.2 40.7 93.4 50.9 106.4 149.0 134.3 147.3 167.4 132.1 120.6 116.3 115.3 114.3 13.7 116.9 197.6 123.6 217.8 122.7 86.2 87.0 85.4 110.2 86.7 91.1 87.1 87.7 88.4 85.8 94.6 89.9 115.4 73.7 62.7 16.6 70.4 121.6 174.0 292.0 97.3 43.2 129.1 216.4 336.1 94.4 119.4 75.4 27.1 194.7 69.0 94.6 189.8 245.3 469.7 94.0 166.4 121.3 71.3 44.8 24.0 247.3 216.5 150.4 64.2 115.0 46.9 84.9 83.6 151.1 146.7 50.5 29.3 113.6 140.4 48.3 93.1 481.2 142.6 67.4 124.5 11.2 113.8 104.0 66.9 17.6 16.8 292.2 100.4 123.0 124.4 392.4 125.1 216.8 107.9 45.3 72.3 126.8 218.4 487.0 413.1 170.9 119.9 143.0 78.4 164.9 157.8 140.4 PF4V1 "CXCL4L1, CXCL4V1, SCYB4V1" ENSG00000109272 "Platelet factor 4 variant 1" P10720 4 73853296-73854483 "Plasma proteins, Predicted secreted proteins" "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.7;lymphoid tissue: 2.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 10.0;Club cells: 2.6;Enteroendocrine cells: 5.3;Macrophages: 6.4;Theca cells: 2.2" "Cancer enhanced" "Detected in some" "renal cancer: 3.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 38 "basophil: 14.2;neutrophil: 9.9" "Lineage enriched" "Detected in single" 45 "granulocytes: 14.2" "Cell line enhanced" "Detected in single" "EFO-21: 1.7" HPA052485 Supported "Secreted to blood" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA052485: AB_2681847" "unprognostic (4.95e-1)" "unprognostic (5.68e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-3)" "unprognostic (9.88e-2)" "unprognostic (1.72e-2)" "unprognostic (1.68e-3)" "unprognostic (2.66e-1)" "unprognostic (6.02e-2)" "unprognostic (2.65e-1)" "unprognostic (1.95e-3)" "unprognostic (1.39e-2)" "unprognostic (2.11e-1)" 0.2 0.0 0.0 0.1 0.2 1.2 0.2 0.0 0.3 0.2 0.1 0.1 1.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.7 0.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.4 1.1 0.0 0.0 0.9 0.0 0.0 2.4 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 9.9 0.0 0.1 0.3 0.0 11.2 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.2 0.1 0.0 10.0 2.6 1.8 0.0 0.0 0.0 0.1 1.9 0.3 0.0 0.2 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.7 2.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 6.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 1.4 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.5 PFDN2 ENSG00000143256 "Prefoldin subunit 2" Q9UHV9 1 161100556-161118055 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 641.9;Suprabasal keratinocytes: 642.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028700, HPA058304" Approved Enhanced Cytosol NA NA 85000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA028700: AB_10603983, HPA058304: AB_2683673" "unprognostic (2.56e-1)" "unprognostic (2.76e-2)" "unprognostic (1.01e-2)" "unprognostic (2.62e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (9.10e-4)" "unprognostic (9.59e-3)" "unprognostic (1.00e-1)" "unprognostic (1.45e-1)" "unprognostic (1.50e-2)" "unprognostic (8.46e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (4.39e-8)" "unprognostic (1.01e-1)" "unprognostic (1.55e-1)" "unprognostic (1.52e-1)" "unprognostic (3.66e-2)" 99.3 80.2 157.9 55.4 167.4 110.5 71.6 168.7 195.3 59.5 144.7 65.7 43.9 59.2 67.2 73.9 57.7 39.7 103.1 159.4 180.9 95.5 103.2 71.0 64.0 171.8 173.3 60.0 49.8 53.5 100.5 57.0 171.8 54.3 41.9 53.6 50.9 45.6 183.3 54.0 46.8 46.3 165.8 54.5 52.8 58.6 169.4 67.1 48.5 114.5 61.3 82.6 59.9 176.0 305.9 205.3 154.0 201.1 141.3 134.1 167.2 218.4 205.1 190.9 150.6 274.2 228.4 204.6 252.4 148.1 185.6 220.0 241.6 279.1 235.2 224.6 236.3 226.1 322.4 394.9 405.9 314.5 217.1 149.0 362.8 305.6 877.0 144.1 222.4 208.9 343.6 142.6 177.8 316.4 237.2 372.6 300.1 359.7 495.8 200.4 154.9 249.8 212.1 186.7 202.5 334.1 168.3 224.3 367.6 200.5 184.9 394.3 188.9 195.4 283.8 245.1 472.2 211.6 226.3 403.5 236.7 214.2 273.1 112.6 104.8 115.5 58.5 107.5 66.9 116.6 72.5 72.1 129.2 120.0 74.7 72.1 54.1 66.1 135.1 201.5 98.8 73.5 157.9 167.4 168.7 195.3 159.4 180.9 171.8 173.3 171.8 165.8 169.4 176.0 178.2 32.1 39.7 13.1 94.6 641.9 320.5 407.2 124.7 76.3 105.5 140.2 125.2 62.9 163.9 115.8 16.7 183.1 114.3 83.6 342.4 168.0 36.1 152.7 140.4 162.3 101.3 93.0 21.5 150.6 242.9 157.2 55.5 176.1 99.5 116.8 97.5 143.5 175.0 21.9 21.8 97.3 248.2 64.2 399.6 26.9 126.5 120.0 184.9 7.5 123.8 94.8 80.3 11.6 62.4 230.3 78.9 110.2 79.1 426.2 86.2 281.2 135.0 77.6 78.9 135.7 298.2 142.7 269.8 153.3 642.6 179.6 113.8 137.3 95.9 355.6 PFDN6 "H2-KE2, HKE2, KE-2, PFD6" ENSG00000204220 "Prefoldin subunit 6" O15212 6 33289302-33298401 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 220.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043032, HPA048123" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 89000 "Cluster 49: Eosinophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Golgi apparatus" Cytosol "HPA043032: AB_2678278, HPA048123: AB_2680273" "unprognostic (1.04e-1)" "unprognostic (1.96e-2)" "unprognostic (7.66e-2)" "unprognostic (1.97e-1)" "unprognostic (2.00e-1)" "unprognostic (1.35e-2)" "unprognostic (8.29e-2)" "unprognostic (3.36e-1)" "unprognostic (1.55e-1)" "prognostic favorable (1.01e-4)" "unprognostic (6.93e-2)" "unprognostic (6.67e-2)" "prognostic unfavorable (8.97e-4)" "unprognostic (1.79e-1)" "unprognostic (4.13e-2)" "unprognostic (1.28e-1)" "unprognostic (4.68e-3)" 45.3 78.2 23.7 13.7 24.4 12.9 45.4 24.2 27.3 49.2 22.6 55.9 9.3 54.8 14.2 70.2 46.2 6.7 85.1 24.4 24.4 78.8 98.1 41.7 15.9 24.6 24.6 45.3 51.7 14.4 62.7 13.6 24.7 51.0 11.6 8.6 47.6 8.0 129.3 49.6 45.3 9.9 23.7 49.9 58.4 91.4 24.0 17.1 45.6 14.7 17.0 55.6 46.7 25.2 49.4 36.0 34.9 56.7 22.7 17.3 43.4 37.2 20.6 48.0 48.7 42.6 24.0 102.8 43.1 20.5 83.5 42.2 69.5 47.6 58.3 49.3 52.9 89.8 39.4 78.3 33.2 56.3 49.3 20.7 50.9 64.8 41.6 28.5 40.2 61.2 107.2 29.6 36.7 36.0 73.9 58.7 47.7 33.0 37.6 71.9 38.0 65.2 58.9 23.4 61.3 83.9 32.1 83.3 61.3 35.0 44.4 65.0 22.5 24.7 36.0 26.0 68.7 71.2 220.3 89.4 20.5 71.9 38.1 1.8 2.6 1.8 1.9 3.2 2.1 3.3 2.3 3.1 2.4 3.2 1.8 2.5 1.1 2.1 3.5 3.5 3.5 1.9 23.7 24.4 24.2 27.3 24.4 24.4 24.6 24.6 24.7 23.7 24.0 25.2 17.4 25.6 8.7 5.2 49.1 55.7 45.2 92.6 43.9 24.5 30.2 17.1 20.7 60.1 51.6 55.2 10.4 127.5 37.6 90.0 121.3 87.6 94.2 106.5 64.7 30.6 50.4 48.4 4.3 103.8 126.1 32.6 44.4 66.9 61.6 32.9 19.2 74.0 79.2 18.5 4.1 75.7 87.5 35.4 45.2 42.7 61.8 37.2 71.2 2.8 66.3 51.0 50.4 1.5 7.1 88.0 71.3 49.2 55.3 53.9 76.4 210.0 53.0 29.0 39.5 43.6 96.3 208.2 60.4 64.3 63.9 110.8 36.9 47.4 82.7 46.7 PHAX "FLJ13193, RNUXA" ENSG00000164902 "Phosphorylated adaptor for RNA export" Q9H814 5 126600925-126627252 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059630, HPA070326" Supported Enhanced Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA059630: AB_2684088, HPA070326: AB_2686253" "unprognostic (1.06e-3)" "unprognostic (4.77e-2)" "unprognostic (1.35e-2)" "unprognostic (2.64e-2)" "unprognostic (6.11e-2)" "unprognostic (1.22e-1)" "unprognostic (4.59e-3)" "unprognostic (9.20e-2)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (2.07e-1)" "unprognostic (2.29e-1)" "unprognostic (4.91e-3)" "unprognostic (7.21e-2)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.07e-2)" 8.2 8.9 9.5 7.1 9.5 4.4 8.1 11.8 10.3 6.9 7.9 6.3 5.0 9.1 7.5 9.0 7.9 7.1 9.7 9.8 8.9 7.6 8.2 6.4 10.9 8.8 9.0 11.4 7.1 8.8 5.1 7.3 9.1 8.4 6.2 8.4 7.3 6.2 12.1 10.6 5.4 8.3 9.0 7.1 6.3 5.6 9.8 7.2 8.7 10.0 10.4 7.7 5.5 10.9 15.5 15.9 13.5 25.6 19.0 18.3 14.9 21.4 16.0 17.6 16.4 21.8 15.1 15.2 19.0 27.7 21.2 12.2 19.1 29.7 25.7 24.7 20.4 13.0 18.5 8.8 11.3 10.8 13.5 18.6 16.4 17.2 15.6 16.5 15.0 8.7 10.4 17.2 27.4 13.3 15.2 13.4 16.9 10.3 12.4 12.1 19.1 12.4 16.4 18.1 17.3 19.9 19.3 16.4 22.7 13.0 22.0 14.7 23.2 29.0 16.1 16.3 32.7 13.3 13.6 17.0 20.8 17.4 21.3 8.7 4.8 6.6 7.1 5.7 8.1 8.2 7.1 7.4 4.8 7.1 7.9 8.3 3.8 10.7 6.1 6.4 6.5 5.5 9.5 9.5 11.8 10.3 9.8 8.9 8.8 9.0 9.1 9.0 9.8 10.9 34.6 25.6 40.2 10.7 36.1 28.6 31.6 72.1 26.7 60.0 27.7 42.2 56.6 20.0 47.3 35.0 39.6 51.5 42.4 29.5 74.3 53.6 37.2 32.8 44.6 36.8 27.5 26.9 14.2 33.3 50.3 41.8 16.3 28.3 46.9 35.0 28.2 28.5 30.1 75.7 14.8 26.9 65.1 17.2 17.6 9.7 42.0 21.9 21.4 5.6 43.4 86.9 37.0 8.0 11.8 40.3 23.1 41.3 29.7 31.9 16.5 56.1 63.3 72.3 46.0 50.3 51.7 64.5 86.4 32.3 25.9 51.4 34.2 43.2 27.7 27.8 PHB PHB1 ENSG00000167085 Prohibitin P35232 17 49404052-49414901 "Plasma proteins, Predicted intracellular proteins" "DNA synthesis, Host-virus interaction" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 473.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 749.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003280 Supported Supported Mitochondria "Intracellular and membrane" NA NA 360000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA003280: AB_1855732" "unprognostic (2.31e-2)" "unprognostic (5.70e-2)" "unprognostic (1.19e-2)" "unprognostic (7.88e-3)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.58e-4)" "prognostic unfavorable (9.91e-4)" "unprognostic (5.81e-2)" "unprognostic (4.40e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (7.36e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.10e-2)" "unprognostic (1.77e-1)" "unprognostic (2.71e-2)" "unprognostic (3.09e-3)" 81.6 88.4 39.2 23.3 42.2 19.8 77.4 44.2 49.8 55.3 54.0 104.5 52.6 68.0 34.1 88.6 55.7 26.9 147.0 40.6 44.4 143.4 120.4 59.0 27.0 43.9 42.5 59.7 62.5 70.1 51.1 33.1 44.1 67.2 60.0 12.1 135.9 44.7 138.1 67.5 68.0 35.7 40.9 61.1 79.7 33.5 41.9 26.2 61.5 98.5 26.8 75.2 59.4 46.0 86.0 339.1 46.4 96.9 81.9 48.3 111.8 69.8 72.3 175.1 122.4 749.5 80.2 119.2 88.1 60.0 67.3 63.4 151.7 135.3 128.4 72.9 327.1 77.7 122.8 361.8 53.0 109.6 58.1 54.9 125.9 130.9 41.6 45.7 87.6 68.6 112.7 27.6 77.5 224.0 106.0 118.5 99.9 135.9 311.1 74.9 144.0 103.8 144.0 116.1 122.1 75.9 35.4 59.1 113.7 71.7 112.2 33.4 58.9 96.3 124.7 78.4 98.4 35.3 65.7 59.1 58.0 125.6 110.7 11.7 45.9 13.4 61.6 53.4 80.5 61.2 56.6 56.3 62.3 46.7 59.4 59.7 8.9 69.0 59.5 155.1 61.4 79.8 39.2 42.2 44.2 49.8 40.6 44.4 43.9 42.5 44.1 40.9 41.9 46.0 88.5 48.1 46.8 8.8 78.3 117.5 147.5 182.6 70.0 44.8 135.7 180.0 8.4 100.1 101.9 84.6 37.5 230.2 144.4 220.8 406.9 233.1 14.0 93.4 85.5 92.6 131.9 77.2 7.8 158.6 278.7 87.8 74.9 131.0 73.0 124.6 61.4 101.8 228.1 21.9 10.0 281.7 223.8 51.9 87.9 24.7 89.5 70.9 158.3 1.9 120.3 83.1 88.6 11.1 15.3 162.8 139.8 115.1 93.0 242.8 151.4 473.6 68.0 42.1 52.6 72.8 306.5 18.0 47.3 107.6 124.0 152.4 75.9 159.9 337.2 161.9 PHF10 "BAF45a, FLJ10975, XAP135" ENSG00000130024 "PHD finger protein 10" Q8WUB8 6 169703902-169725566 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055649 Supported Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA055649: AB_2682875" "unprognostic (1.74e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-2)" "unprognostic (4.25e-2)" "unprognostic (4.45e-2)" "unprognostic (6.76e-3)" "prognostic unfavorable (3.42e-4)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" "prognostic favorable (1.12e-5)" "unprognostic (5.92e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.63e-1)" "unprognostic (6.82e-2)" "unprognostic (2.43e-1)" "unprognostic (2.76e-2)" 41.9 78.5 49.1 39.0 55.4 53.4 40.9 52.2 53.9 43.1 46.3 49.2 32.3 40.0 39.2 46.7 39.7 34.6 46.5 43.0 54.2 38.4 52.4 40.4 61.7 52.5 56.2 80.7 41.0 47.7 36.3 43.7 54.8 48.4 34.6 59.1 44.5 44.7 81.3 50.9 40.7 33.4 56.6 49.8 42.7 41.7 55.0 53.2 48.6 63.7 61.3 42.3 41.9 57.4 31.2 30.7 119.2 125.5 40.7 24.5 49.0 41.2 37.3 49.8 54.3 88.9 31.4 91.1 24.4 29.2 31.7 38.4 92.5 45.3 72.0 73.3 82.1 91.1 54.8 116.9 41.5 134.2 5.4 18.5 46.7 32.1 29.4 82.3 80.2 64.4 102.7 57.5 36.0 53.4 25.6 115.0 37.6 68.3 18.9 121.0 84.4 73.7 62.1 32.5 56.7 75.9 56.4 18.4 41.5 49.7 36.3 158.6 54.0 28.1 46.6 36.3 53.2 50.7 46.1 112.3 36.7 88.6 45.6 1.6 1.4 3.2 1.5 1.5 1.4 2.6 2.7 2.1 1.4 1.7 2.6 2.8 0.2 1.2 1.6 1.2 1.8 0.8 49.1 55.4 52.2 53.9 43.0 54.2 52.5 56.2 54.8 56.6 55.0 57.4 42.5 25.6 30.1 17.9 24.5 29.8 22.7 13.3 13.1 12.1 38.1 31.8 59.3 35.8 23.7 11.0 41.7 14.8 25.9 11.0 13.7 12.5 15.3 32.1 27.4 28.2 25.9 7.4 14.9 12.6 8.9 27.6 12.8 42.1 6.3 38.1 29.3 27.5 11.6 11.8 19.0 22.8 18.3 13.9 28.7 9.7 22.4 21.5 19.6 28.1 11.8 33.4 10.3 17.6 33.6 17.1 19.4 21.1 16.4 27.6 18.6 12.4 22.7 26.8 19.7 27.9 53.1 18.9 22.0 21.2 23.4 17.4 21.2 33.2 20.0 27.4 PHRF1 "KIAA1542, PPP1R125, RNF221" ENSG00000070047 "PHD and ring finger domains 1" Q9P1Y6 11 576470-612222 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 24.2;MOLT-4: 39.0;U-138 MG: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019867, HPA062933" Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "HPA019867: AB_1852416, HPA062933: AB_2684907" "unprognostic (5.67e-2)" "unprognostic (1.00e-2)" "unprognostic (3.94e-2)" "unprognostic (9.65e-2)" "unprognostic (1.79e-3)" "unprognostic (1.25e-2)" "prognostic unfavorable (6.00e-5)" "unprognostic (6.28e-2)" "unprognostic (2.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-1)" "unprognostic (3.50e-2)" "unprognostic (2.33e-1)" "unprognostic (3.47e-2)" "unprognostic (1.94e-1)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" 14.3 17.5 1.2 1.0 2.6 3.1 13.9 1.4 3.6 14.4 0.9 14.2 0.0 13.2 1.3 18.7 13.5 1.1 14.0 1.1 1.1 12.5 26.5 14.5 0.0 1.5 1.1 14.6 14.4 0.0 13.9 0.0 1.5 14.5 0.0 0.2 13.8 1.2 18.7 22.2 16.3 1.0 0.5 17.6 14.3 17.9 1.7 0.1 13.5 0.0 2.1 12.6 14.4 1.7 2.6 1.6 0.4 7.9 0.0 0.4 1.5 6.2 0.5 0.6 0.0 0.0 0.2 14.8 14.7 0.3 0.3 3.1 0.2 0.0 0.0 4.6 10.5 0.9 0.0 24.2 0.0 1.7 1.6 3.6 0.0 0.0 3.9 0.0 0.3 13.1 3.5 0.0 0.0 0.8 39.0 0.5 1.9 0.2 7.2 1.4 1.5 0.0 0.0 0.3 11.4 1.8 4.3 12.9 0.1 8.9 0.4 5.1 1.2 21.2 7.4 0.5 1.5 2.7 3.7 1.5 0.5 1.2 0.0 0.0 0.3 0.0 0.3 0.2 0.3 0.1 0.4 0.5 0.3 0.4 0.4 0.2 0.5 0.3 0.1 0.4 0.3 0.2 1.2 2.6 1.4 3.6 1.1 1.1 1.5 1.1 1.5 0.5 1.7 1.7 11.5 6.4 11.1 10.1 14.9 17.6 10.1 7.4 18.2 12.2 11.6 7.9 7.8 11.5 8.2 14.7 8.4 8.0 17.1 24.1 0.0 11.6 2.1 14.0 12.9 11.9 11.4 16.0 5.9 10.6 8.0 11.3 23.4 17.7 5.1 14.7 4.6 17.5 9.5 20.2 6.6 14.2 2.0 10.6 11.7 2.8 11.8 13.1 3.6 10.3 11.3 8.2 23.7 4.5 8.4 18.0 12.2 10.5 17.5 12.4 21.8 7.0 12.5 16.0 13.1 14.1 12.2 26.4 28.0 17.4 17.8 8.9 17.2 13.0 14.9 13.6 PICALM "CALM, CLTH" ENSG00000073921 "Phosphatidylinositol binding clathrin assembly protein" Q13492 11 85957175-86069882 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 500.3;Oligodendrocytes: 709.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 40.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019053, HPA019061" Enhanced Enhanced Vesicles NA NA 40000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA019053: AB_1855361, HPA019061: AB_1855362" "unprognostic (9.27e-3)" "unprognostic (7.29e-2)" "unprognostic (3.51e-1)" "unprognostic (6.83e-2)" "unprognostic (5.13e-2)" "unprognostic (1.93e-1)" "unprognostic (5.36e-3)" "unprognostic (9.02e-3)" "unprognostic (9.80e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.31e-1)" "prognostic favorable (2.02e-6)" "unprognostic (1.26e-2)" "unprognostic (5.21e-3)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" 183.5 62.5 97.1 120.4 162.1 111.4 111.5 119.3 118.7 86.4 43.8 86.3 106.3 79.3 52.4 109.1 66.1 127.0 87.9 91.7 110.8 168.5 147.0 99.4 82.7 125.2 130.7 94.4 80.6 120.6 36.5 157.2 131.6 73.1 83.1 71.5 62.3 93.6 75.8 74.2 115.5 135.3 106.0 126.5 73.0 64.9 120.7 93.1 75.7 101.9 96.7 139.5 73.5 194.7 167.0 78.4 121.1 85.9 185.5 188.8 228.5 211.7 274.7 164.4 143.0 310.7 222.4 126.0 210.8 342.6 171.1 134.6 129.4 154.2 232.8 38.6 45.0 364.9 101.5 98.9 185.6 87.2 158.3 166.6 161.7 308.7 253.3 275.1 178.7 85.9 239.1 103.0 305.2 98.2 103.9 76.8 66.9 269.0 42.7 69.8 182.2 91.1 312.5 139.2 72.9 58.7 258.4 85.4 68.7 156.5 115.6 67.0 196.9 298.6 104.1 355.0 170.2 36.7 107.1 118.4 70.8 64.6 206.6 6.4 13.5 7.5 5.7 11.7 4.9 3.1 4.2 8.0 11.4 2.1 4.2 4.0 40.6 7.1 12.5 3.9 6.4 5.3 97.1 162.1 119.3 118.7 91.7 110.8 125.2 130.7 131.6 106.0 120.7 194.7 147.1 35.3 58.9 134.5 33.3 116.0 44.4 33.0 30.1 20.8 34.8 28.6 46.4 42.9 34.3 71.7 12.5 42.9 43.9 64.2 31.3 57.7 59.3 32.3 32.8 98.7 25.1 88.8 144.7 37.6 127.1 44.6 34.1 50.9 48.2 23.2 71.4 52.3 85.0 40.4 140.7 30.1 30.5 142.8 229.2 95.4 35.8 127.4 60.5 500.3 92.1 22.6 32.0 188.0 709.3 90.2 55.3 43.6 39.1 49.5 71.4 84.0 41.0 16.3 78.9 36.4 92.7 17.3 14.1 34.4 96.5 41.3 38.9 23.6 30.6 77.7 PIGX FLJ20522 ENSG00000163964 "Phosphatidylinositol glycan anchor biosynthesis class X" Q8TBF5 3 196639775-196736007 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 87.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 87.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029409, HPA073301" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029409: AB_10610280, HPA073301: " "unprognostic (8.83e-2)" "prognostic favorable (2.12e-4)" "unprognostic (2.14e-1)" "unprognostic (2.42e-3)" "unprognostic (9.25e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (7.45e-5)" "unprognostic (1.91e-1)" "unprognostic (3.97e-2)" "unprognostic (1.11e-2)" "unprognostic (3.18e-2)" "unprognostic (4.02e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "unprognostic (1.53e-1)" "unprognostic (1.46e-1)" "unprognostic (2.01e-1)" 10.5 10.3 14.4 10.4 15.6 9.0 9.9 14.7 16.7 7.5 19.5 10.8 9.1 8.3 12.4 10.3 7.9 8.3 9.6 15.2 16.7 12.2 8.2 7.2 7.1 15.1 15.8 6.8 9.0 19.6 12.7 8.3 14.8 12.8 10.1 17.4 9.9 10.5 17.1 10.4 9.1 11.2 16.0 6.8 7.6 6.0 16.2 11.6 9.2 14.1 10.9 8.7 7.6 16.7 39.4 18.7 21.4 18.1 22.7 15.3 12.6 18.1 20.7 19.3 20.5 13.7 25.6 20.3 63.6 15.4 25.1 22.2 19.5 16.6 23.1 18.6 19.6 21.0 12.8 12.6 19.2 20.6 34.6 15.1 25.7 17.1 15.7 16.3 12.7 36.5 11.7 38.6 21.0 30.1 59.2 32.1 12.8 30.7 18.3 31.1 27.6 29.5 24.6 11.5 24.4 29.2 31.8 23.9 29.7 16.9 71.8 20.3 8.2 18.1 9.2 25.6 29.5 57.0 70.4 41.1 20.7 26.9 21.5 39.6 7.5 87.5 3.3 10.8 3.0 4.6 3.1 4.6 7.7 5.5 3.7 3.2 18.8 8.7 11.6 3.3 4.4 4.1 14.4 15.6 14.7 16.7 15.2 16.7 15.1 15.8 14.8 16.0 16.2 16.7 14.2 19.2 16.3 13.7 16.4 17.1 30.1 5.5 31.9 34.9 28.3 19.2 12.6 21.5 8.4 29.5 47.9 21.4 31.6 20.8 35.2 7.9 30.5 17.2 23.5 16.9 15.7 15.8 17.7 5.6 20.9 22.0 9.2 17.9 12.0 19.3 17.5 16.6 20.1 33.7 23.7 17.0 8.2 21.4 25.4 22.7 28.0 18.1 21.4 15.9 25.0 50.0 32.0 12.1 14.5 5.2 12.5 35.0 20.1 33.8 27.1 32.5 10.2 39.1 26.3 23.6 28.1 27.1 36.0 29.3 15.9 11.6 21.2 22.7 25.7 23.0 PITPNA "PITPN, VIB1A" ENSG00000174238 "Phosphatidylinositol transfer protein alpha" Q00169 17 1517718-1562792 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000528 Uncertain Approved Vesicles,Cytosol NA NA 190000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" Cytosol Vesicles "HPA000528: AB_1079622" "unprognostic (1.54e-1)" "unprognostic (6.63e-2)" "unprognostic (2.43e-1)" "prognostic favorable (2.29e-4)" "unprognostic (7.88e-2)" "unprognostic (8.89e-3)" "unprognostic (2.37e-1)" "unprognostic (1.37e-1)" "unprognostic (7.33e-2)" "unprognostic (3.17e-2)" "prognostic favorable (1.80e-6)" "unprognostic (7.41e-2)" "prognostic favorable (9.35e-4)" "unprognostic (1.72e-1)" "unprognostic (1.23e-1)" "unprognostic (8.10e-2)" "unprognostic (6.81e-3)" 42.5 36.8 41.7 61.0 45.4 93.6 41.7 46.6 56.2 50.7 51.0 47.2 56.7 55.3 58.8 76.6 65.9 45.4 39.1 43.8 50.5 40.0 39.0 46.9 40.4 62.4 45.4 32.1 33.9 60.8 33.1 50.2 58.4 54.2 55.6 47.6 84.1 61.7 24.7 93.2 88.9 54.3 41.9 42.4 40.5 44.8 52.2 33.2 64.7 22.7 57.1 51.9 41.8 43.0 64.9 70.5 70.5 61.0 72.1 78.8 110.7 68.9 75.8 70.6 50.9 78.7 25.7 81.8 62.4 94.0 45.4 79.5 64.2 68.4 97.0 68.3 69.2 44.7 61.4 37.0 70.6 31.1 51.6 58.9 90.6 70.5 73.1 74.4 118.4 67.1 63.3 44.9 74.8 36.5 80.1 28.5 49.3 103.4 34.1 63.8 27.2 46.9 70.5 73.5 25.2 55.2 83.2 59.1 51.4 70.5 52.2 24.7 113.8 44.8 39.5 126.4 95.5 27.2 49.8 28.8 77.4 47.9 58.4 3.7 2.4 3.2 2.1 2.7 4.0 4.3 3.1 2.8 3.5 3.1 2.9 2.6 8.0 3.7 1.9 2.7 5.2 1.7 41.7 45.4 46.6 56.2 43.8 50.5 62.4 45.4 58.4 41.9 52.2 43.0 29.3 35.3 35.0 28.7 14.1 31.0 17.5 12.0 12.0 36.4 30.0 30.2 23.9 17.2 17.1 25.8 8.4 43.4 26.9 41.2 13.7 16.0 12.0 50.5 48.4 31.4 22.1 15.6 42.4 18.5 47.3 19.1 13.3 36.5 19.0 16.8 34.6 30.2 40.5 40.4 46.3 27.7 10.2 29.9 49.7 16.8 12.5 36.4 19.6 36.5 36.6 40.2 13.4 12.1 16.0 26.0 22.9 21.8 15.7 33.0 78.0 16.3 21.7 18.4 6.6 18.8 45.1 35.8 34.7 37.8 41.8 120.0 14.9 24.7 25.3 27.0 PLA1A ps-PLA1 ENSG00000144837 "Phospholipase A1 member A" Q53H76 3 119597875-119629811 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 138.4;parathyroid gland: 65.8;seminal vesicle: 67.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 14.7;Endothelial cells: 14.3;Hepatocytes: 26.0;Langerhans cells: 15.6;Peritubular cells: 14.3" "Group enriched" "Detected in many" 5 "liver cancer: 14.8;melanoma: 55.4;prostate cancer: 24.2;renal cancer: 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "SK-MEL-30: 25.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059740 Approved "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" "Secreted in other tissues" NA NA 420000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytoplasmic bodies" Nucleoplasm "HPA059740: AB_2684118" "unprognostic (1.35e-1)" "prognostic favorable (2.81e-7)" "unprognostic (2.24e-2)" "unprognostic (3.46e-2)" "unprognostic (3.18e-2)" "unprognostic (1.94e-2)" "unprognostic (1.11e-2)" "unprognostic (2.43e-1)" "unprognostic (3.87e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" "unprognostic (9.09e-2)" "unprognostic (1.55e-3)" "unprognostic (9.53e-3)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" "unprognostic (2.67e-1)" 4.9 0.7 12.1 3.5 11.3 0.3 3.4 11.6 16.3 4.7 26.8 2.7 1.1 4.7 138.4 1.5 5.7 2.8 4.9 12.5 12.0 7.7 39.6 21.2 15.6 13.2 12.3 1.1 3.7 65.8 1.7 9.8 13.2 9.1 2.5 1.0 3.5 67.2 16.2 0.8 3.5 8.8 13.4 1.0 4.4 3.7 14.7 1.6 6.9 3.1 8.7 3.9 1.9 12.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.8 0.3 0.5 0.1 0.0 0.2 0.0 0.0 25.0 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 12.1 11.3 11.6 16.3 12.5 12.0 13.2 12.3 13.2 13.4 14.7 12.4 6.5 0.0 1.7 0.0 0.0 0.6 0.5 0.4 0.6 0.0 0.1 0.1 2.8 2.8 1.0 14.7 0.0 0.2 0.1 0.0 1.9 4.7 6.6 0.1 0.1 14.3 1.8 0.0 0.2 2.2 0.0 1.6 0.0 0.9 1.3 0.7 7.9 26.0 1.6 0.0 0.1 0.1 0.0 1.0 15.6 3.2 0.3 5.4 1.8 4.7 4.2 0.0 0.0 0.0 0.0 1.3 0.6 14.3 0.0 0.5 0.0 5.1 7.5 0.1 0.0 0.9 5.9 0.0 0.2 0.0 0.6 1.9 0.1 0.0 0.1 0.2 PLAA "DOA1, FLJ11281, FLJ12699, PLA2P, PLAP" ENSG00000137055 "Phospholipase A2 activating protein" Q9Y263 9 26903372-26947242 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005035, HPA020994, HPA020996" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 12000000 "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB005035: AB_562036, HPA020994: AB_1855444, HPA020996: AB_1855445" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (4.00e-3)" "unprognostic (5.00e-1)" "unprognostic (1.61e-1)" "unprognostic (4.06e-2)" "unprognostic (4.50e-3)" "unprognostic (2.48e-1)" "unprognostic (5.54e-2)" "prognostic favorable (7.87e-4)" "unprognostic (3.24e-2)" "unprognostic (1.44e-1)" "unprognostic (9.29e-3)" "unprognostic (1.86e-2)" "unprognostic (6.68e-2)" "unprognostic (1.39e-2)" "unprognostic (5.10e-1)" 16.0 16.9 8.5 16.2 9.0 42.0 12.6 9.3 11.2 11.3 9.6 15.2 13.6 17.5 13.4 18.8 9.8 13.0 18.8 9.5 9.7 15.4 21.5 12.8 15.0 8.1 8.3 11.0 12.0 16.9 8.0 16.0 9.0 12.9 15.9 14.1 10.9 12.5 50.3 12.1 12.6 19.3 8.3 13.3 12.7 20.4 8.1 18.0 15.9 29.1 18.1 14.7 11.2 10.2 64.6 37.0 46.1 46.3 30.4 38.2 34.6 58.4 33.1 43.9 42.2 13.1 29.8 56.9 48.0 45.0 30.6 25.1 45.8 46.0 47.7 75.7 19.1 35.2 57.9 25.5 30.9 28.8 46.3 34.4 27.0 53.2 38.8 33.0 44.3 41.7 22.1 56.6 47.6 26.6 56.3 28.1 66.8 33.2 31.6 39.4 28.7 34.4 33.5 37.6 29.2 49.9 31.3 36.5 19.1 44.8 25.5 22.5 54.3 0.2 53.8 28.5 48.3 18.4 43.7 59.5 30.8 40.4 23.4 21.9 12.7 21.0 11.0 18.2 12.6 14.3 11.5 11.4 13.1 11.9 10.3 12.0 11.4 14.9 21.2 6.6 18.0 9.6 8.5 9.0 9.3 11.2 9.5 9.7 8.1 8.3 9.0 8.3 8.1 10.2 10.8 16.0 11.2 18.3 18.8 11.0 11.3 14.6 17.1 9.1 7.5 6.6 23.8 5.7 16.1 9.2 0.0 24.9 14.9 11.9 9.8 17.6 27.7 10.2 12.3 17.1 9.6 25.9 31.9 16.2 26.6 11.5 15.8 14.7 40.6 13.2 12.5 10.7 20.7 5.0 30.8 8.6 14.2 15.8 8.2 6.6 8.7 17.5 1.8 21.5 15.9 9.5 16.5 24.6 32.1 15.2 8.7 8.2 23.1 10.6 11.0 12.3 12.7 6.7 19.7 13.0 34.1 28.1 24.9 20.9 9.5 49.3 18.3 21.5 12.6 11.6 PLEKHO1 "CKIP-1, OC120" ENSG00000023902 "Pleckstrin homology domain containing O1" Q53GL0 1 150149183-150164720 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 202.3" "Cell type enhanced" "Detected in many" "Early spermatids: 245.9;Langerhans cells: 159.2;Late spermatids: 390.5;Macrophages: 147.9;monocytes: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061018 Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA061018: AB_2684416" "unprognostic (1.41e-2)" "unprognostic (7.04e-3)" "unprognostic (2.01e-2)" "unprognostic (1.78e-2)" "unprognostic (3.23e-2)" "unprognostic (4.77e-2)" "unprognostic (1.62e-2)" "unprognostic (8.33e-2)" "unprognostic (3.84e-2)" "unprognostic (3.18e-2)" "unprognostic (8.71e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.47e-11)" "unprognostic (9.30e-2)" "unprognostic (1.72e-1)" "unprognostic (1.87e-1)" "unprognostic (6.52e-2)" 27.7 43.2 49.9 53.9 50.1 17.9 22.6 52.8 61.6 32.3 45.5 202.3 17.8 50.7 5.2 17.5 43.5 20.6 59.3 49.5 47.9 15.9 8.7 34.9 49.5 49.8 48.1 28.1 5.1 4.1 14.9 15.1 48.0 45.5 11.5 4.2 11.0 16.2 39.6 11.2 58.4 40.4 48.9 59.9 55.8 83.2 48.0 33.9 13.0 15.2 26.0 97.5 23.6 48.9 14.3 3.4 46.3 36.0 14.4 12.7 3.8 24.8 32.9 31.8 28.1 1.0 0.4 0.4 4.7 28.5 23.9 1.2 23.3 1.1 10.3 86.7 12.1 2.8 1.9 8.9 27.1 20.0 77.7 18.5 1.0 39.8 6.2 30.6 30.6 38.5 5.4 35.9 43.9 6.7 76.0 40.0 43.7 0.0 6.4 68.1 25.2 16.2 5.6 4.1 28.8 46.9 2.0 0.2 18.7 22.1 2.4 19.4 43.4 20.8 24.1 21.9 30.1 14.0 0.4 9.2 83.4 0.2 8.2 2.6 25.9 0.5 5.6 24.8 6.0 20.0 8.2 5.9 20.1 17.2 5.6 4.7 30.9 4.1 23.4 27.3 6.7 9.2 49.9 50.1 52.8 61.6 49.5 47.9 49.8 48.1 48.0 48.9 48.0 48.9 23.5 35.3 8.9 32.3 65.1 21.5 92.7 2.9 4.6 7.9 11.8 17.9 36.4 2.8 2.9 0.0 0.0 1.7 97.5 0.5 1.9 8.8 245.9 17.9 50.2 58.9 17.8 4.2 13.5 7.8 3.3 29.4 4.6 22.0 5.7 24.5 42.5 1.8 107.1 8.4 24.3 0.9 10.2 85.5 159.2 390.5 17.4 147.9 24.9 21.5 151.1 34.0 23.7 9.0 1.6 10.7 0.0 24.5 23.7 50.1 0.2 0.5 1.3 6.2 72.3 7.5 105.0 122.5 17.5 2.9 14.2 1.5 45.6 8.6 0.4 23.0 PMPCB "MPPB, MPPP52" ENSG00000105819 "Peptidase, mitochondrial processing subunit beta" O75439 7 103297435-103329511 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040674, HPA074168" Approved Enhanced Mitochondria No No 19000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA040674: AB_10961998, HPA074168: AB_2686671" "prognostic favorable (2.79e-4)" "unprognostic (3.11e-1)" "unprognostic (7.18e-3)" "unprognostic (3.03e-1)" "unprognostic (3.65e-2)" "unprognostic (1.72e-1)" "unprognostic (1.06e-1)" "unprognostic (7.67e-2)" "unprognostic (7.74e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.42e-3)" "prognostic favorable (2.95e-8)" "unprognostic (2.59e-2)" "unprognostic (9.79e-2)" "unprognostic (2.40e-1)" "unprognostic (4.39e-2)" 30.8 42.0 16.9 22.3 18.2 53.5 32.5 18.9 22.1 33.3 24.7 33.4 38.0 29.9 26.2 27.7 29.3 25.1 44.9 18.8 18.1 47.4 46.1 22.6 36.4 16.5 16.6 35.4 41.1 39.7 22.4 25.8 17.6 31.5 33.2 25.4 30.6 28.1 34.8 33.2 32.4 26.3 17.2 28.2 35.8 26.7 17.4 30.2 33.4 38.2 33.9 29.3 28.4 19.9 30.2 42.8 49.9 69.4 28.5 57.1 38.0 26.7 45.6 54.3 62.8 47.7 33.7 76.9 41.7 47.9 58.0 37.5 59.7 43.2 49.2 26.4 69.4 26.4 74.0 61.6 35.0 35.0 30.6 53.4 40.5 41.8 39.6 51.3 28.8 55.9 52.5 77.9 48.5 71.1 59.2 82.0 59.2 60.4 52.4 42.7 34.3 79.4 50.3 54.2 62.2 76.5 37.3 108.6 55.8 49.5 45.3 49.1 24.9 48.3 57.9 85.1 52.3 57.4 79.9 61.8 35.7 59.3 38.2 16.7 19.3 13.2 18.3 21.4 20.1 25.9 21.1 18.5 24.7 19.3 26.1 21.7 5.7 17.9 19.7 12.6 30.2 22.3 16.9 18.2 18.9 22.1 18.8 18.1 16.5 16.6 17.6 17.2 17.4 19.9 32.0 32.1 36.9 27.1 54.5 36.7 68.2 123.2 51.8 31.6 41.3 37.3 70.4 41.5 70.7 27.6 22.9 125.6 55.9 35.8 72.4 75.6 106.3 38.4 37.0 37.1 27.1 65.8 36.8 73.2 61.3 42.5 35.7 35.0 60.2 49.9 31.1 53.7 54.6 23.5 33.9 48.1 75.3 49.4 30.7 24.0 51.9 42.4 26.6 18.7 92.5 35.8 58.7 35.7 44.4 59.7 45.4 49.7 56.1 35.2 60.4 127.5 58.2 37.9 65.7 48.6 73.5 125.4 56.4 47.1 37.5 124.9 55.9 63.3 59.1 62.2 POLE2 DPE2 ENSG00000100479 "DNA polymerase epsilon 2, accessory subunit" P56282 14 49643555-49688422 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 21.0;Spermatogonia: 24.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" HPA027555 Uncertain Supported "Nucleoplasm,Nuclear bodies,Vesicles" No No "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear bodies" Vesicles "HPA027555: AB_10610282" "unprognostic (1.42e-1)" "unprognostic (6.57e-3)" "unprognostic (3.53e-2)" "unprognostic (7.44e-2)" "unprognostic (2.04e-2)" "unprognostic (4.99e-3)" "unprognostic (7.60e-3)" "unprognostic (2.32e-3)" "unprognostic (1.10e-3)" "unprognostic (2.69e-2)" "unprognostic (1.88e-2)" "unprognostic (1.37e-3)" "unprognostic (5.13e-11)" "unprognostic (9.97e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (1.50e-3)" 0.9 0.9 0.5 5.1 0.3 18.2 3.0 0.5 0.6 2.1 0.0 3.8 2.5 2.5 0.7 3.7 1.0 0.9 0.6 0.2 0.2 0.7 3.1 1.2 5.1 0.2 0.4 1.0 0.8 0.7 0.5 3.0 0.2 1.4 4.5 3.0 1.0 0.7 0.5 3.5 3.6 2.3 0.3 1.5 2.1 4.1 0.2 5.5 0.9 0.9 6.2 1.4 1.9 0.6 37.2 18.6 34.3 16.3 1.7 9.9 18.2 20.4 10.4 31.9 36.7 19.3 27.5 23.6 11.6 11.6 17.5 22.3 35.3 12.8 36.9 27.4 19.6 35.4 20.6 23.9 0.8 41.2 14.6 2.8 0.8 18.5 2.9 4.1 19.0 30.5 30.9 14.3 31.6 32.7 43.6 28.4 20.2 30.9 42.6 35.9 31.7 21.0 11.6 20.6 24.8 14.3 20.5 11.9 6.7 16.5 24.5 15.8 6.7 5.3 38.5 21.4 16.9 10.7 22.7 52.7 9.8 30.1 20.9 0.0 0.0 0.2 0.2 0.0 0.1 0.3 0.2 0.4 0.1 0.2 0.0 0.2 0.0 0.9 0.0 0.2 0.7 0.1 0.5 0.3 0.5 0.6 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.6 2.0 3.2 0.5 4.2 2.4 4.8 2.1 1.9 2.2 0.8 1.5 1.1 1.2 1.5 1.3 0.0 0.0 9.1 1.0 2.2 0.0 1.3 1.2 0.8 2.6 1.5 1.2 21.0 9.5 1.5 10.6 2.7 1.1 1.5 0.0 4.3 5.0 5.5 5.5 0.0 11.9 2.8 0.0 1.9 1.6 0.8 1.5 1.1 1.8 7.5 1.0 2.0 4.1 12.1 11.5 0.8 0.5 3.0 5.7 1.9 1.1 1.2 0.9 3.1 0.0 2.1 7.4 5.3 24.4 6.0 3.7 3.4 1.7 1.8 4.7 1.5 POLR1C "AC40, RPA39, RPA40, RPA5, RPAC1, RPC40" ENSG00000171453 "RNA polymerase I and III subunit C" O15160 6 43509702-43562419 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 306.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031010 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "HPA031010: AB_10603131" "unprognostic (2.84e-1)" "unprognostic (1.67e-1)" "unprognostic (3.15e-1)" "unprognostic (6.57e-2)" "unprognostic (7.01e-2)" "unprognostic (3.59e-1)" "unprognostic (6.69e-3)" "unprognostic (1.09e-3)" "unprognostic (2.00e-3)" "unprognostic (1.90e-2)" "unprognostic (2.05e-1)" "unprognostic (7.32e-2)" "prognostic unfavorable (4.17e-4)" "unprognostic (1.20e-2)" "unprognostic (4.69e-2)" "unprognostic (3.01e-1)" "unprognostic (6.41e-2)" 15.5 19.2 16.0 12.3 16.0 7.7 20.3 15.7 20.9 15.3 19.8 18.4 13.1 15.1 15.7 21.3 21.0 9.5 13.3 16.0 16.4 17.6 17.7 11.0 13.9 15.9 15.9 14.4 15.5 17.1 13.8 12.2 16.2 14.4 15.5 6.6 15.8 12.0 15.3 20.5 10.9 14.8 16.0 12.7 14.6 20.1 16.3 12.5 16.1 13.4 20.8 23.4 15.5 17.1 76.0 61.7 26.6 72.3 40.0 43.0 42.1 45.3 33.5 49.7 42.2 82.5 25.2 85.2 48.3 44.2 42.5 45.2 64.7 57.6 57.6 45.4 67.7 58.3 57.2 115.7 50.1 90.0 39.1 38.7 54.8 67.9 85.4 29.4 39.6 35.4 136.9 24.5 44.0 106.4 47.4 65.0 49.2 306.8 52.9 31.9 41.8 57.6 60.7 104.1 49.0 32.8 39.6 34.1 62.2 19.4 36.9 77.9 47.6 35.3 48.1 38.4 72.3 35.1 85.0 146.0 24.1 60.9 40.0 5.7 30.0 4.6 34.1 24.0 46.5 51.1 40.4 34.1 42.4 55.0 55.1 49.6 2.7 41.7 20.5 38.6 32.7 34.0 16.0 16.0 15.7 20.9 16.0 16.4 15.9 15.9 16.2 16.0 16.3 17.1 13.0 12.8 17.7 9.8 24.9 61.8 50.6 34.3 42.1 8.2 24.0 23.6 5.2 17.2 30.4 5.5 6.2 29.7 15.3 11.3 15.6 26.7 13.5 23.4 15.9 18.6 13.1 12.8 13.6 24.4 18.9 21.5 25.0 14.2 14.0 14.4 15.7 11.9 13.3 5.0 12.3 17.4 28.5 5.2 17.0 8.3 11.5 8.5 21.4 11.2 8.3 7.1 14.4 14.1 10.2 21.0 11.5 11.7 13.1 29.2 5.0 27.5 48.5 15.4 6.6 29.1 45.6 34.4 43.3 26.4 40.9 13.5 17.4 21.5 19.9 37.0 POLR2F "HRBP14.4, RPB6" ENSG00000100142 "RNA polymerase II, I and III subunit F" P61218 22 37952607-38041915 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 4 "melanoma: 1.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000827, CAB009882" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "CAB009882: AB_2299942, HPA000827: AB_1079834" "unprognostic (8.27e-2)" "unprognostic (7.50e-2)" "unprognostic (1.51e-3)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (2.73e-3)" "unprognostic (2.85e-1)" "unprognostic (5.87e-2)" "unprognostic (4.06e-1)" "unprognostic (1.40e-3)" "unprognostic (1.11e-4)" "unprognostic (9.08e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-1)" "unprognostic (7.86e-2)" 52.5 61.1 73.4 34.6 92.3 38.9 50.8 77.5 90.2 59.5 56.9 64.9 37.7 53.2 24.8 58.7 50.2 19.5 91.8 74.2 91.2 58.2 118.6 41.6 31.0 87.9 83.9 60.9 47.5 76.5 62.7 30.2 82.6 47.7 28.7 16.8 56.1 39.6 111.0 45.8 42.3 28.8 75.3 36.4 57.6 48.8 86.8 36.7 54.7 68.4 26.3 53.1 52.7 123.7 150.7 176.2 120.6 128.7 141.1 81.7 109.4 138.0 81.0 141.4 130.5 210.0 51.8 117.4 99.1 120.3 138.3 106.4 166.9 135.7 67.1 143.0 303.7 107.3 181.3 289.1 125.9 213.6 67.0 112.4 99.8 186.3 72.1 71.2 118.7 130.4 208.9 93.7 101.9 220.2 168.4 258.2 174.3 175.4 134.7 162.3 110.4 134.5 77.4 94.8 180.6 67.2 129.5 88.9 215.3 69.6 62.9 144.3 110.5 119.8 173.9 150.4 158.1 106.0 178.0 247.9 122.4 107.9 138.4 118.9 92.9 140.8 83.8 90.4 78.5 95.8 71.9 81.8 86.3 71.3 63.1 63.7 122.8 113.7 78.5 123.3 103.4 85.3 73.4 92.3 77.5 90.2 74.2 91.2 87.9 83.9 82.6 75.3 86.8 123.7 82.6 38.5 85.9 9.4 73.2 204.3 113.9 205.4 63.7 26.7 133.8 168.7 0.3 101.5 122.5 121.4 25.0 243.5 70.5 148.7 193.7 160.0 117.0 96.0 117.2 94.8 117.2 109.6 9.9 159.5 303.4 97.4 58.1 82.4 90.0 90.0 98.6 304.4 178.5 28.6 10.7 143.1 116.0 94.2 102.9 42.0 159.7 65.9 225.9 2.8 102.3 99.4 111.2 9.5 99.0 182.4 152.9 151.2 65.7 137.3 196.6 306.5 114.3 33.3 157.8 90.1 197.1 237.0 241.0 106.0 224.3 211.9 82.4 82.7 145.7 121.2 POTEE "A26C1, A26C1A, CT104.2, POTE-2, POTE2, POTE2gamma" ENSG00000188219 "POTE ankyrin domain family member E" Q6S8J3 2 131218067-131265278 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 1.9;testis: 1.4" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 6.0;Breast glandular cells: 2.5;Prostatic glandular cells: 2.8;Smooth muscle cells: 2.4;Spermatocytes: 4.9;Spermatogonia: 2.0;Urothelial cells: 2.2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.2;K-562: 1.4;U-2 OS: 2.3" "HPA041264, HPA041271, HPA043260" Uncertain NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "HPA041264: AB_2677383, HPA041271: AB_2677386, HPA043260: AB_2678396" "unprognostic (3.13e-2)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (1.38e-1)" "unprognostic (5.04e-2)" "unprognostic (2.59e-3)" "unprognostic (3.84e-2)" "unprognostic (1.05e-1)" "unprognostic (6.61e-3)" "unprognostic (5.77e-2)" "unprognostic (7.60e-2)" "unprognostic (7.46e-3)" "unprognostic (1.19e-1)" "unprognostic (1.84e-1)" "unprognostic (1.72e-1)" "unprognostic (1.90e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.1 0.5 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.2 1.1 0.5 0.4 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.0 0.2 0.0 0.0 2.5 1.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.8 0.0 0.7 0.2 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.2 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.1 2.4 4.9 2.0 0.0 0.1 0.4 0.1 0.2 0.0 2.2 POTEF "A26C1B, POTE2alpha, POTEACTIN" ENSG00000196604 "POTE ankyrin domain family member F" A5A3E0 2 130073535-130129222 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 1.6;testis: 1.7" "Cell type enhanced" "Detected in some" "Melanocytes: 1.8;NK-cells: 1.0;Smooth muscle cells: 1.3;Spermatocytes: 2.2;Spermatogonia: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.7;BEWO: 2.0;CACO-2: 2.3;MCF7: 1.8;U-2 OS: 5.6;U-266/70: 2.7" "HPA041264, HPA041271, HPA043260" Uncertain NA NA 1900000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA041264: AB_2677383, HPA041271: AB_2677386, HPA043260: AB_2678396" "unprognostic (1.36e-1)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (2.98e-1)" "unprognostic (1.01e-1)" "unprognostic (1.18e-2)" "unprognostic (8.13e-3)" "unprognostic (1.44e-2)" "unprognostic (2.90e-2)" "unprognostic (1.16e-1)" "unprognostic (3.38e-1)" "unprognostic (2.23e-1)" "unprognostic (3.50e-1)" "unprognostic (1.02e-1)" "unprognostic (4.48e-1)" "unprognostic (1.05e-2)" "unprognostic (9.35e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 2.7 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.8 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.1 2.7 0.8 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 1.6 0.1 0.2 0.0 0.0 0.2 1.6 0.9 0.5 0.5 1.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.3 2.2 1.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 POTEM "ACT, P704P, POTE14beta" ENSG00000222036 "POTE ankyrin domain family member M" A6NI47 14 18967434-19003752 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "prostate: 18.7" "Cell type enhanced" "Detected in single" "Langerhans cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.2;K-562: 4.2;U-2 OS: 7.4" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 71: Testis - DNA repair" "Cluster 9: U-2 OS - Unknown function" "Cluster 10: Non-specific - Unknown function" "unprognostic (6.16e-2)" 0.1 0.2 0.7 0.2 0.3 0.2 0.3 0.4 0.8 0.2 0.0 0.1 0.2 0.2 0.2 0.1 0.2 0.2 0.3 0.3 0.5 0.1 0.0 0.2 0.2 0.4 0.1 0.3 0.2 0.1 0.0 0.4 0.4 18.7 0.1 1.1 0.3 0.1 0.2 0.5 0.1 0.1 0.0 0.3 0.2 4.1 0.3 0.1 0.6 0.1 0.1 0.1 0.0 0.9 0.7 0.7 0.3 0.6 0.1 0.1 3.2 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.4 0.1 0.4 0.2 0.1 0.2 0.1 0.1 0.2 0.3 1.0 1.0 0.0 0.3 0.8 0.1 0.2 0.4 0.0 0.2 0.1 0.1 4.2 1.8 0.2 0.7 0.4 0.3 0.8 0.0 0.5 0.3 0.3 0.8 0.2 0.2 0.2 1.1 0.3 1.7 0.1 0.9 2.1 0.2 0.5 0.3 7.4 0.4 0.3 0.8 1.5 0.1 0.2 0.3 0.4 0.7 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.7 0.3 0.4 0.8 0.3 0.5 0.4 0.1 0.4 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 POU3F4 "BRN4, DFN3, DFNX2, OTF9" ENSG00000196767 "POU class 3 homeobox 4" X 83508290-83512127 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 11.9" "Cell type enriched" "Detected in some" 6 "Collecting duct cells: 11.0" "Cancer enriched" "Detected in single" 21 "glioma: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 99 "AF22: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA062295 Supported Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA062295: AB_2732681" "unprognostic (5.73e-2)" "unprognostic (2.00e-1)" 0.0 0.0 2.3 0.0 11.9 0.0 0.0 2.6 4.5 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.5 2.5 1.6 0.0 0.0 0.0 2.9 5.5 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 11.9 2.6 4.5 1.5 2.5 2.9 5.5 2.5 2.6 3.4 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPID CYP-40 ENSG00000171497 "Peptidylprolyl isomerase D" Q08752 4 158709127-158723396 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Protein transport, Transport" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019520, HPA019692" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA 480000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA019520: AB_1847400, HPA019692: AB_1847401" "unprognostic (4.26e-2)" "unprognostic (2.03e-2)" "unprognostic (8.91e-3)" "unprognostic (8.17e-3)" "unprognostic (1.50e-1)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.62e-2)" "unprognostic (4.72e-2)" "unprognostic (5.92e-2)" "unprognostic (4.54e-2)" "unprognostic (1.46e-2)" "unprognostic (2.66e-3)" "unprognostic (8.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.64e-1)" "unprognostic (1.09e-1)" 26.8 38.3 38.0 24.4 40.2 25.1 22.8 40.4 77.6 25.4 46.4 33.9 50.6 24.2 19.0 27.7 24.1 18.8 49.6 40.1 44.2 39.5 87.6 19.8 28.6 39.0 39.4 24.2 31.7 17.0 28.6 21.6 40.2 23.5 20.3 36.2 23.3 18.7 88.9 36.1 45.3 18.9 39.6 29.1 29.0 24.1 42.2 24.3 23.9 45.5 25.8 27.4 24.0 46.9 46.7 42.3 41.8 57.7 60.7 45.2 63.1 44.9 24.3 40.3 30.4 55.4 30.9 48.9 19.7 42.0 63.4 35.1 127.9 51.5 48.8 162.9 44.4 87.5 36.5 76.9 46.8 55.6 63.0 28.9 41.2 34.6 51.5 52.0 44.6 81.9 111.0 84.4 45.5 44.6 80.0 49.9 57.9 75.5 55.8 35.9 20.7 41.7 44.6 23.0 70.2 47.1 33.8 69.2 65.6 60.0 31.9 52.2 43.7 40.1 45.3 44.7 60.2 48.3 107.2 62.0 51.1 59.4 41.1 68.8 23.9 55.2 31.1 35.4 36.0 22.3 30.2 29.1 26.4 25.4 30.9 32.0 32.9 40.5 37.7 26.9 37.0 28.0 38.0 40.2 40.4 77.6 40.1 44.2 39.0 39.4 40.2 39.6 42.2 46.9 29.2 6.4 13.4 13.1 24.8 10.1 29.7 17.5 9.1 30.2 19.1 20.8 59.7 25.8 27.9 27.6 22.9 41.5 38.7 17.1 37.2 39.2 39.0 66.1 39.9 25.1 19.6 17.4 24.3 23.0 49.5 24.3 14.3 28.5 32.3 24.4 17.2 18.5 41.9 75.7 28.6 28.3 22.4 17.0 14.7 23.1 20.5 26.0 14.2 9.4 51.6 23.3 48.4 15.1 28.3 29.5 27.4 22.6 22.3 31.6 39.7 33.7 62.3 32.3 6.6 17.7 58.2 96.0 77.5 16.9 11.8 47.6 33.7 33.7 32.0 20.2 PPIG "CARS-Cyp, SCAF10, SRCyp" ENSG00000138398 "Peptidylprolyl isomerase G" Q13427 2 169584342-169641406 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021788, HPA057469" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" Cytosol "HPA021788: AB_1847408, HPA057469: AB_2683445" "unprognostic (2.70e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (3.49e-2)" "unprognostic (1.55e-3)" "unprognostic (3.66e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-3)" "unprognostic (2.47e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (4.56e-4)" "unprognostic (5.23e-2)" "unprognostic (3.29e-1)" "unprognostic (3.41e-2)" "unprognostic (3.39e-2)" 26.0 23.2 23.1 28.4 22.1 54.2 27.5 28.8 58.6 27.6 22.9 26.3 26.6 28.8 31.5 27.5 23.6 22.0 25.6 21.5 29.9 29.2 47.1 24.7 36.9 24.6 25.6 26.5 21.2 32.6 25.8 28.0 24.3 27.9 26.0 29.3 26.5 22.9 27.6 25.4 29.7 21.7 22.9 32.3 27.4 20.1 23.7 36.1 29.9 26.2 35.4 26.3 26.5 25.9 56.4 25.5 70.8 35.9 35.4 42.5 63.7 58.9 42.3 45.0 45.9 66.3 58.9 94.8 52.5 44.1 55.5 50.5 56.6 48.4 65.6 68.0 45.7 129.9 36.7 88.3 34.4 136.8 58.9 36.6 54.0 58.5 64.6 40.6 50.4 53.5 142.7 76.2 49.5 43.5 101.0 81.9 100.8 45.3 25.1 90.7 71.7 90.5 53.9 81.2 60.5 41.2 63.4 47.2 68.9 52.9 44.2 78.7 52.7 53.9 43.7 38.4 52.6 41.1 65.3 126.8 38.5 68.1 54.1 31.9 22.5 36.7 22.8 25.1 26.7 32.9 30.9 29.2 18.2 38.4 33.4 27.6 40.4 21.1 31.4 30.0 26.8 17.0 23.1 22.1 28.8 58.6 21.5 29.9 24.6 25.6 24.3 22.9 23.7 25.9 159.7 221.2 175.1 53.5 188.8 151.4 191.4 185.9 101.3 204.6 120.8 156.1 148.4 107.2 169.5 93.8 54.2 170.0 160.1 91.6 80.3 103.1 11.0 104.6 142.3 141.1 104.8 163.5 82.4 103.3 177.0 142.4 66.8 126.3 179.1 115.8 121.7 181.2 151.7 220.4 81.8 135.8 116.0 130.3 126.5 15.6 142.0 129.6 110.3 46.9 152.4 137.6 133.9 53.8 69.7 93.9 118.0 146.7 130.1 161.8 121.1 113.8 132.2 109.1 164.3 150.2 193.9 276.4 183.8 108.3 172.8 205.5 166.7 147.1 149.9 167.7 PPIH "CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP" ENSG00000171960 "Peptidylprolyl isomerase H" O43447 1 42658335-42676758 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059019 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "HPA059019: AB_2683885" "unprognostic (7.93e-3)" "unprognostic (5.49e-3)" "unprognostic (2.53e-2)" "unprognostic (6.42e-2)" "unprognostic (3.79e-2)" "unprognostic (1.95e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (1.09e-1)" "unprognostic (2.37e-2)" "unprognostic (1.82e-2)" "unprognostic (2.84e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.78e-9)" "unprognostic (6.59e-3)" "unprognostic (4.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" 22.9 23.2 22.1 27.8 23.1 56.8 27.7 23.7 29.5 24.8 20.8 33.2 24.4 23.5 25.4 36.4 23.5 17.9 25.8 23.0 22.5 22.1 17.5 22.4 44.5 22.2 22.0 25.8 19.2 18.3 13.4 24.7 22.7 21.2 32.8 22.4 23.9 18.3 19.8 27.5 27.8 21.5 21.8 32.3 23.4 22.9 22.5 60.3 26.0 21.1 50.4 26.6 25.8 23.3 105.8 66.4 80.1 113.3 24.9 51.5 101.4 67.6 50.1 127.4 114.4 98.1 111.8 171.5 85.9 52.8 61.7 82.3 150.8 108.2 133.9 150.2 119.7 156.4 104.4 98.6 21.4 322.0 90.7 31.2 57.5 117.9 90.6 49.1 60.6 161.2 205.7 91.7 63.8 84.2 250.1 451.0 200.4 100.4 77.7 136.8 150.2 152.2 64.1 64.8 59.2 113.5 59.6 101.1 77.4 100.8 54.5 465.0 48.1 53.2 143.1 77.0 171.7 60.0 140.2 319.6 62.8 294.9 94.8 29.7 15.1 33.3 35.0 23.5 33.3 33.6 35.7 39.9 20.7 32.9 36.1 43.5 3.6 36.4 21.8 25.9 38.2 25.0 22.1 23.1 23.7 29.5 23.0 22.5 22.2 22.0 22.7 21.8 22.5 23.3 31.3 19.2 20.7 9.8 48.1 28.9 48.2 51.7 38.7 10.0 30.1 44.4 14.1 11.5 25.8 22.0 4.2 62.5 37.7 15.7 45.0 29.4 33.2 23.4 27.4 25.1 21.5 49.8 12.7 26.4 104.5 25.5 27.5 21.6 31.0 46.9 19.2 11.2 52.1 5.0 9.6 27.3 34.6 18.6 25.6 7.3 29.2 28.5 16.0 9.4 26.2 22.2 52.5 11.6 11.6 25.8 17.6 21.4 45.6 28.0 16.1 34.1 19.6 16.1 19.7 21.5 42.0 19.7 32.3 54.6 21.5 37.9 42.7 46.4 40.0 38.7 PPIL3 CyPJ ENSG00000240344 "Peptidylprolyl isomerase like 3" Q9H2H8 2 200870907-200889303 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040765, HPA062187" Approved Approved Nucleoplasm,Nucleoli NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA040765: AB_2677125, HPA062187: AB_2684706" "unprognostic (8.96e-3)" "unprognostic (6.07e-2)" "unprognostic (5.34e-2)" "unprognostic (8.16e-2)" "unprognostic (2.69e-2)" "unprognostic (9.61e-2)" "unprognostic (8.31e-2)" "unprognostic (8.05e-2)" "unprognostic (1.40e-2)" "prognostic favorable (1.19e-4)" "unprognostic (5.23e-2)" "unprognostic (6.60e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.14e-1)" "unprognostic (5.96e-2)" "unprognostic (2.21e-2)" "unprognostic (4.87e-2)" 13.0 16.4 15.2 19.8 14.9 35.1 25.4 17.0 22.3 15.7 13.9 19.0 14.6 20.2 28.4 18.6 22.5 13.0 18.2 14.6 16.8 18.4 21.9 15.0 32.2 15.7 15.5 35.4 12.1 14.0 14.9 17.7 16.8 15.1 19.5 25.8 17.1 18.2 18.0 18.0 18.1 12.4 15.4 17.5 19.0 21.1 15.5 30.1 20.8 11.1 32.5 16.2 12.5 18.2 19.9 18.3 53.0 23.5 42.5 90.8 17.5 32.0 35.3 37.1 37.2 13.0 37.5 19.5 32.0 35.4 41.9 24.6 19.3 38.1 33.2 41.4 43.8 84.0 48.3 90.6 21.3 79.7 39.8 32.7 37.7 30.3 47.1 62.0 25.3 38.4 67.4 46.3 46.3 32.4 61.7 67.2 32.9 19.8 28.9 23.3 30.5 29.1 49.6 30.4 22.2 21.1 31.3 29.9 51.7 62.3 24.6 36.9 34.2 51.4 28.8 31.2 26.2 45.5 51.0 94.2 39.6 36.2 33.7 36.2 17.5 19.7 17.5 16.4 25.5 35.2 20.9 17.7 30.9 26.7 25.3 27.6 4.5 31.8 23.1 25.6 30.3 14.6 15.2 14.9 17.0 22.3 14.6 16.8 15.7 15.5 16.8 15.4 15.5 18.2 12.5 0.0 11.5 16.0 33.6 31.7 43.1 71.5 37.5 12.0 23.7 28.2 18.5 15.7 30.4 16.5 10.4 50.3 24.8 9.7 56.7 26.0 44.1 16.1 21.4 16.2 9.5 25.5 19.3 16.1 51.6 22.1 16.3 13.4 26.0 17.2 13.6 19.4 47.0 3.3 18.1 25.3 48.8 32.1 59.1 9.5 36.7 26.8 28.4 9.4 30.2 23.1 37.0 15.1 19.7 18.2 18.1 28.2 24.5 15.9 25.4 59.7 28.7 11.9 19.7 18.2 39.6 45.7 22.6 34.5 46.3 30.8 31.1 8.9 29.4 35.6 PPP1R11 "CFAP255, HCG-V, HCGV, TCTE5, Tctex5" ENSG00000204619 "Protein phosphatase 1 regulatory inhibitor subunit 11" O60927 6 30066709-30070333 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 696.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 8 "cerebral cortex: 8.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 51.5;AN3-CA: 65.6;fHDF/TERT166: 48.6;GAMG: 47.4;HBEC3-KT: 53.6;JURKAT: 76.7;RPTEC TERT1: 47.4;U-266/84: 64.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043266, HPA060174" Approved Approved Vesicles NA NA 43000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA043266: AB_2678400, HPA060174: AB_2684216" "unprognostic (2.00e-2)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (4.24e-2)" "unprognostic (3.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.77e-2)" "unprognostic (1.18e-1)" "unprognostic (2.81e-1)" "unprognostic (1.74e-3)" "unprognostic (3.33e-2)" "unprognostic (2.68e-1)" "unprognostic (8.36e-3)" "unprognostic (1.74e-1)" "unprognostic (3.31e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-3)" 44.5 41.1 0.7 0.0 0.7 1.9 41.4 0.6 8.8 44.4 0.6 55.5 11.6 49.6 33.1 52.1 37.3 11.8 51.0 0.7 0.7 62.3 47.5 43.7 5.4 0.9 0.7 41.8 45.1 2.2 29.2 5.8 0.8 46.3 0.7 7.9 42.8 0.0 50.4 42.9 50.7 0.0 0.6 39.8 59.5 41.5 0.7 9.7 42.3 0.0 11.8 51.6 42.7 1.1 51.5 0.0 0.0 65.6 29.4 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 48.6 47.4 0.0 0.0 53.6 0.0 1.0 34.5 42.6 0.0 0.0 0.0 3.0 3.9 0.0 0.0 0.0 0.7 0.0 0.0 76.7 0.5 2.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.4 47.4 29.0 0.0 0.0 0.7 35.5 4.8 26.8 0.0 0.0 0.0 0.0 0.3 4.1 1.5 30.7 64.9 26.7 0.7 0.0 0.0 11.5 4.1 12.4 4.7 9.3 4.5 6.8 5.3 6.5 2.2 7.2 4.9 7.0 2.8 3.9 7.9 3.2 8.4 6.8 0.7 0.7 0.6 8.8 0.7 0.7 0.9 0.7 0.8 0.6 0.7 1.1 38.2 19.2 20.2 2.6 57.8 52.8 80.0 77.2 29.0 29.3 47.7 32.8 18.8 52.9 49.7 40.5 6.2 56.0 39.2 111.5 95.9 142.2 242.1 19.8 24.2 44.3 53.7 32.4 10.1 136.3 119.9 27.0 53.5 31.8 78.6 21.4 45.7 28.0 65.7 13.5 9.0 83.8 77.3 49.7 53.8 696.0 32.3 43.5 62.2 3.7 75.4 58.4 92.7 6.0 7.6 136.5 114.1 40.3 42.2 66.6 139.6 93.3 38.7 33.1 39.5 27.2 89.4 61.9 23.2 39.0 66.5 75.2 52.4 16.5 51.8 94.9 PPP1R2B "MGC87149, PPP1R2P3" ENSG00000231989 "PPP1R2 family member B" Q6NXS1 5 156850295-156852528 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 121 "testis: 21.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "U-266/84: 1.2" "HPA043729, HPA059420" Approved Nucleoplasm,Cytosol NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA043729: AB_2678639, HPA059420: AB_2684009" "unprognostic (1.96e-1)" "unprognostic (2.42e-1)" "unprognostic (1.12e-1)" "unprognostic (2.32e-1)" "unprognostic (9.36e-2)" "unprognostic (1.46e-2)" "unprognostic (1.89e-1)" "unprognostic (4.47e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-2)" "unprognostic (1.77e-1)" "unprognostic (1.33e-1)" "unprognostic (8.51e-2)" "unprognostic (1.41e-1)" "unprognostic (1.06e-2)" "unprognostic (1.07e-2)" "unprognostic (5.19e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 PPP3CB "CALNA2, CALNB, CNA2, PP2Bbeta" ENSG00000107758 "Protein phosphatase 3 catalytic subunit beta" P16298 10 73436433-73496024 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 379.3;tongue: 179.7" "Cell type enhanced" "Detected in all" "Excitatory neurons: 119.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008233, HPA008823" Uncertain Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA008233: AB_1855661, HPA008823: AB_2668148" "unprognostic (3.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "unprognostic (8.93e-2)" "unprognostic (4.28e-2)" "prognostic unfavorable (9.59e-4)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (2.12e-2)" "prognostic favorable (6.96e-5)" "unprognostic (4.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" 44.8 37.5 40.5 29.8 51.1 19.8 32.1 49.5 63.1 30.3 26.7 41.4 24.2 40.3 34.5 33.1 30.9 28.3 41.3 56.9 29.5 28.1 21.8 23.5 34.9 25.4 25.2 39.6 25.3 39.2 30.6 25.5 28.7 39.1 29.6 57.0 26.6 39.8 379.3 26.3 22.6 48.2 27.2 25.3 24.3 29.0 29.1 32.9 23.5 179.7 36.1 34.3 24.3 44.9 53.7 29.0 50.9 53.0 71.4 98.3 24.5 48.0 65.7 46.1 45.4 18.6 26.8 47.1 15.3 70.0 21.8 28.1 41.6 36.9 64.5 66.6 34.0 20.3 25.0 35.5 42.7 45.2 40.2 70.1 43.5 43.6 58.1 84.7 32.3 40.6 25.6 54.0 94.1 16.9 40.7 41.6 20.7 23.3 83.8 26.9 27.7 22.4 45.1 25.6 27.2 31.5 28.1 69.5 36.4 42.1 52.4 43.2 35.6 36.6 33.7 29.5 66.1 35.8 105.3 33.0 45.3 64.0 21.3 2.2 2.0 3.5 4.0 2.7 4.8 2.7 4.3 4.4 2.1 2.3 3.4 5.1 1.1 3.5 1.7 4.0 7.8 1.9 40.5 51.1 49.5 63.1 56.9 29.5 25.4 25.2 28.7 27.2 29.1 44.9 23.0 3.2 14.3 72.5 31.6 25.6 29.8 13.2 27.3 54.8 25.7 16.9 48.9 14.3 12.8 18.4 20.9 21.0 23.7 11.1 62.6 18.1 11.8 20.0 24.2 21.5 42.6 30.7 119.5 19.4 16.8 32.6 20.4 18.8 21.0 35.4 18.9 14.2 20.3 38.7 111.0 13.2 18.3 31.7 24.2 9.9 33.5 25.2 26.6 51.5 29.6 34.8 18.6 79.4 54.4 16.7 12.9 29.0 34.1 27.1 13.4 34.2 17.6 30.1 6.6 41.8 36.4 43.8 49.2 32.1 31.5 22.2 27.3 28.4 13.1 22.1 PPT2 ENSG00000221988 "Palmitoyl-protein thioesterase 2" Q9UMR5 6 32153441-32163678 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 33.6;Smooth muscle cells: 27.8;Syncytiotrophoblasts: 23.3" "Cancer enhanced" "Detected in all" "melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 21.3;HEK 293: 27.9;SK-MEL-30: 29.4" HPA000414 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA000414: " "unprognostic (1.90e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.03e-5)" "unprognostic (1.62e-1)" "unprognostic (6.75e-3)" "unprognostic (2.92e-3)" "unprognostic (6.41e-3)" "unprognostic (7.12e-2)" "unprognostic (2.56e-3)" "unprognostic (5.28e-3)" "unprognostic (1.12e-2)" "unprognostic (2.75e-3)" "unprognostic (5.09e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.24e-3)" 19.0 18.0 1.1 2.1 1.1 0.1 18.7 1.1 4.8 26.5 1.0 23.7 1.6 22.0 2.6 28.2 21.7 0.0 24.5 1.1 1.1 22.1 13.9 14.3 1.7 1.1 1.2 46.2 14.3 0.0 13.7 3.9 1.1 17.2 1.5 6.2 14.9 0.0 19.0 29.4 14.9 1.3 1.1 13.3 21.0 8.3 1.1 1.9 14.6 0.2 1.0 18.1 24.2 1.3 0.0 0.0 0.0 0.4 21.3 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.2 1.6 0.7 5.3 2.6 5.0 0.0 0.0 27.9 4.0 0.0 0.0 0.0 3.5 1.8 4.0 1.6 0.0 7.3 3.8 0.0 14.9 0.0 1.8 1.7 13.0 4.6 0.0 0.0 0.9 0.0 6.3 5.8 0.0 14.3 0.0 1.6 5.4 8.7 5.2 29.4 15.2 0.0 3.7 0.8 0.0 11.4 0.0 0.0 0.8 12.6 3.0 5.8 2.2 3.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.7 0.0 0.1 1.1 1.1 1.1 4.8 1.1 1.1 1.1 1.2 1.1 1.1 1.1 1.3 9.4 0.0 0.5 0.0 0.7 3.3 2.9 2.6 5.7 12.4 4.2 2.9 6.8 2.8 2.8 3.7 16.7 14.5 4.4 2.4 1.9 1.8 0.3 4.5 4.3 7.6 4.9 17.4 0.0 3.0 9.2 6.3 1.5 5.0 0.0 33.6 6.4 4.4 3.0 3.3 0.0 2.6 2.0 1.3 1.3 1.1 4.1 1.1 7.2 0.0 0.2 9.5 3.1 0.0 0.0 1.8 3.8 3.0 1.7 1.4 1.4 3.1 0.6 6.1 0.0 3.6 27.8 4.0 6.7 4.4 2.3 23.3 1.4 5.0 3.0 1.5 PRDX1 "NKEFA, PAGA" ENSG00000117450 "Peroxiredoxin 1" Q06830 1 45510914-45542732 "Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 2690.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004682, HPA007730" Approved Approved Mitochondria NA NA 110000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "CAB004682: AB_437046, HPA007730: AB_1855204" "unprognostic (1.28e-2)" "unprognostic (4.64e-1)" "unprognostic (2.22e-2)" "unprognostic (3.65e-1)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "unprognostic (4.68e-2)" "unprognostic (3.05e-2)" "unprognostic (2.90e-1)" "unprognostic (2.39e-2)" "unprognostic (5.99e-2)" "unprognostic (2.88e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.89e-4)" 277.8 362.9 642.4 290.2 667.1 86.7 454.3 700.7 747.3 314.1 627.0 326.7 501.4 255.3 459.4 945.8 306.3 297.4 542.9 613.0 700.8 785.5 841.2 340.2 371.4 712.1 706.3 255.5 122.7 214.6 210.0 353.3 711.6 256.0 327.1 347.3 348.6 307.2 571.4 296.5 402.1 329.3 713.5 265.8 355.5 143.7 671.4 262.8 802.3 477.7 603.3 393.2 375.3 766.6 1028.1 1743.7 735.2 942.9 828.4 701.9 1459.3 1134.8 1144.1 1183.0 964.3 932.3 429.2 899.1 1125.9 1237.6 1448.6 967.6 1640.2 1101.3 1193.0 696.9 1266.4 678.6 2042.8 2484.7 361.0 793.6 848.9 610.4 813.6 1201.7 283.8 657.7 1409.7 1044.0 1271.8 292.7 1225.2 829.4 1053.7 772.5 2339.8 2241.0 1867.3 1863.6 934.0 1177.7 2211.5 872.4 987.5 495.1 1035.3 2524.2 73.3 2157.3 760.6 631.1 1208.1 474.8 1071.9 1034.4 1541.5 206.1 1220.5 1678.2 791.4 537.9 278.7 469.3 325.6 111.6 155.7 367.1 205.4 253.8 246.8 209.3 293.9 221.6 150.3 166.6 12.1 123.8 407.5 195.9 438.2 416.3 642.4 667.1 700.7 747.3 613.0 700.8 712.1 706.3 711.6 713.5 671.4 766.6 530.7 522.4 259.0 48.3 330.1 607.3 1115.3 1161.1 745.0 161.3 387.0 510.9 54.9 397.5 685.2 617.9 104.3 1258.6 151.5 339.3 946.9 1015.7 19.7 662.7 281.2 437.8 174.5 304.2 15.5 442.8 1773.2 462.0 500.0 435.5 325.3 463.2 326.3 875.2 1467.4 206.9 17.1 295.0 545.3 366.9 980.7 44.2 498.6 534.8 581.7 12.2 545.7 416.4 62.8 24.1 90.5 804.4 384.9 410.7 612.8 1100.9 995.0 2690.9 919.1 402.2 309.0 279.0 982.6 84.5 329.2 1346.9 528.6 1114.9 270.9 499.4 398.8 1462.7 PRKG2 "cGKII, PKG2, PRKGR2" ENSG00000138669 "Protein kinase cGMP-dependent 2" Q13237 4 81087370-81215117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.1;prostate: 9.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 35.3;Excitatory neurons: 32.6;Inhibitory neurons: 66.1;Oligodendrocyte precursor cells: 106.6;Proximal enterocytes: 19.7;Smooth muscle cells: 29.8" "Group enriched" "Detected in some" 4 "melanoma: 4.1;prostate cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 5.0;ASC TERT1: 3.8;HEL: 21.2;hTCEpi: 4.0;SCLC-21H: 6.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007386, CAB018739" Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 56: Intestine - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "CAB018739: AB_2284387, HPA007386: AB_1079678" "unprognostic (6.14e-2)" "unprognostic (2.77e-1)" "unprognostic (2.14e-1)" "unprognostic (5.01e-4)" "unprognostic (4.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.13e-1)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (1.48e-1)" "unprognostic (8.27e-2)" "unprognostic (2.33e-1)" "unprognostic (1.58e-1)" "unprognostic (4.00e-3)" "unprognostic (1.06e-1)" 1.0 0.2 2.1 0.2 1.5 0.5 1.5 0.5 1.7 1.0 0.0 2.4 9.6 0.4 0.3 2.8 0.3 0.2 4.3 1.5 1.6 0.5 0.0 3.3 0.2 3.5 2.7 0.0 1.4 0.0 2.2 0.0 3.8 9.6 2.8 0.3 0.3 3.4 0.0 1.2 13.1 0.5 2.2 0.0 0.9 0.9 6.0 1.0 0.9 0.0 0.4 0.5 0.6 1.0 0.1 0.3 0.1 0.0 5.0 3.8 0.0 0.3 0.0 0.0 0.0 0.4 2.4 0.0 0.2 0.9 0.0 0.1 0.3 1.5 0.0 0.4 0.0 21.2 0.6 0.1 0.0 0.0 0.0 0.5 4.0 0.0 0.0 1.0 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.1 0.9 0.6 0.4 0.0 0.0 0.1 0.0 0.9 6.3 0.0 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.1 1.5 0.5 1.7 1.5 1.6 3.5 2.7 3.8 2.2 6.0 1.0 0.3 35.3 2.6 1.0 0.3 0.0 0.9 0.1 1.2 0.0 0.3 0.1 4.9 0.0 2.0 0.0 0.0 0.0 0.1 5.5 0.0 0.2 10.3 0.3 0.6 0.1 0.0 8.0 32.6 0.0 0.1 2.5 0.0 0.1 1.3 0.1 0.0 0.0 0.1 0.0 66.1 1.7 0.0 0.0 0.0 2.2 0.0 0.1 0.0 12.2 0.1 0.0 0.0 106.6 1.1 0.9 9.2 0.0 0.5 0.8 19.7 0.2 0.8 0.0 0.0 0.1 29.8 0.0 1.3 0.8 0.1 0.0 0.4 0.0 0.7 0.3 PRMT1 "ANM1, HCP1, HRMT1L2" ENSG00000126457 "Protein arginine methyltransferase 1" Q99873 19 49675786-49689029 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 444.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022550, HPA069769, HPA072136" Supported Supported Nucleoplasm NA NA 8500 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB022550: , HPA069769: AB_2686193, HPA072136: AB_2686490" "unprognostic (1.88e-2)" "unprognostic (1.28e-2)" "unprognostic (3.00e-2)" "unprognostic (3.84e-1)" "unprognostic (4.13e-2)" "unprognostic (3.33e-2)" "prognostic unfavorable (8.04e-5)" "unprognostic (3.43e-2)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (3.59e-2)" "unprognostic (1.05e-1)" "unprognostic (7.19e-3)" "unprognostic (2.21e-1)" "unprognostic (3.66e-2)" "unprognostic (4.73e-2)" "unprognostic (1.10e-2)" 79.7 102.2 62.5 76.2 63.2 65.0 76.7 68.1 74.7 107.0 59.4 87.2 55.1 115.4 44.5 90.7 109.7 49.8 149.2 65.7 71.1 77.9 61.8 76.5 94.0 66.5 65.2 106.7 66.3 65.6 101.1 65.3 68.8 77.1 45.5 71.3 67.6 73.9 242.6 74.8 71.8 74.0 66.3 91.6 69.4 78.4 71.3 79.6 70.9 163.2 84.5 92.6 81.6 68.7 262.5 584.9 396.5 481.7 105.4 118.7 208.4 163.7 283.1 461.8 394.0 439.5 202.2 425.9 119.0 193.4 181.1 188.0 337.3 345.8 200.1 333.7 580.5 311.5 156.4 484.6 256.8 378.7 214.2 166.7 169.3 259.2 369.0 154.8 277.1 338.3 334.0 293.2 182.5 394.1 493.2 467.0 420.5 324.9 375.6 344.8 319.9 388.8 264.0 540.9 440.0 342.4 188.9 193.2 103.4 126.9 146.8 220.6 173.9 269.9 262.5 125.4 398.6 280.0 457.4 429.3 165.7 271.0 289.8 25.0 76.8 37.5 104.0 93.8 129.6 198.9 95.4 111.0 131.5 171.6 105.2 103.3 14.8 162.3 71.9 158.9 97.7 132.5 62.5 63.2 68.1 74.7 65.7 71.1 66.5 65.2 68.8 66.3 71.3 68.7 169.7 3.2 10.3 15.7 112.4 207.0 228.7 444.9 123.5 228.9 71.3 96.8 17.2 40.0 117.3 44.1 106.3 195.6 74.4 45.1 127.2 204.0 5.4 88.9 124.5 167.8 115.2 38.3 9.8 135.2 177.5 101.7 51.5 87.5 54.7 154.2 109.6 22.1 104.1 129.5 15.8 74.5 227.9 27.0 125.7 19.4 104.1 52.9 112.1 15.9 149.4 119.3 57.7 14.6 20.2 125.6 45.6 89.1 117.8 263.0 35.2 87.5 62.8 168.7 92.1 89.7 236.3 66.8 121.8 94.9 158.8 235.2 76.8 200.7 105.0 183.2 PRPF40A "FBP-11, FBP11, FLAF1, FLJ20585, FNBP3, HIP10, HYPA, NY-REN-6, Prp40" ENSG00000196504 "Pre-mRNA processing factor 40 homolog A" O75400 2 152651593-152717997 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038272, HPA038273" Approved Enhanced "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA038272: AB_2675923, HPA038273: AB_10671526" "unprognostic (1.81e-1)" "unprognostic (2.91e-1)" "unprognostic (4.31e-3)" "unprognostic (4.49e-3)" "unprognostic (1.55e-3)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.62e-2)" "unprognostic (3.61e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.58e-5)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (1.80e-2)" "unprognostic (2.32e-1)" "unprognostic (3.24e-2)" "unprognostic (2.05e-2)" 16.7 16.7 9.0 24.7 9.8 45.0 21.5 14.3 10.4 16.8 9.4 24.2 23.0 18.6 15.7 27.6 18.0 17.4 15.3 8.7 10.3 18.9 21.7 17.4 30.4 10.4 8.7 18.9 19.7 24.0 10.5 22.2 10.9 18.4 20.9 16.7 16.6 15.0 22.8 21.0 23.0 17.4 9.9 20.7 22.2 25.5 8.7 31.5 24.6 20.0 28.1 27.1 15.1 12.3 63.4 62.9 68.9 70.8 39.1 51.8 95.5 61.8 55.2 86.0 78.9 120.0 57.8 130.9 88.0 62.7 49.2 63.8 90.8 74.3 91.6 72.4 78.6 121.8 55.7 79.9 50.7 135.4 81.6 41.7 61.9 113.8 127.3 52.4 67.5 60.8 133.2 60.6 52.9 38.4 57.2 63.4 102.9 41.2 75.8 110.4 73.3 86.9 43.7 99.8 82.2 56.0 73.9 53.5 67.6 50.6 46.8 85.4 79.1 90.3 56.6 51.9 81.4 38.8 67.7 130.6 57.9 78.2 56.1 87.6 70.1 91.7 66.7 86.5 62.3 65.5 62.1 60.7 79.4 70.3 65.5 58.8 61.1 70.4 101.1 84.8 58.8 80.1 9.0 9.8 14.3 10.4 8.7 10.3 10.4 8.7 10.9 9.9 8.7 12.3 98.5 112.2 118.5 48.3 120.3 141.0 120.0 117.9 101.3 65.0 73.6 70.6 64.4 55.8 122.1 53.3 73.0 123.1 123.7 67.2 49.0 110.0 150.3 101.0 126.6 97.4 78.3 105.6 56.4 111.5 155.9 96.4 74.9 121.0 123.4 111.0 53.9 72.5 109.2 60.6 53.3 81.5 87.5 95.7 114.5 36.4 69.3 125.5 55.2 44.0 184.1 62.7 107.1 44.7 71.3 128.3 86.8 79.7 112.1 131.7 69.5 75.7 152.6 75.2 98.6 104.8 132.1 239.0 121.4 141.6 151.7 132.2 119.9 164.9 103.7 148.4 PSEN2 "AD3L, AD4, PS2, STM2" ENSG00000143801 "Presenilin 2" P49810 1 226870184-226927726 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ionocytes: 36.7;Syncytiotrophoblasts: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "unprognostic (3.40e-2)" "unprognostic (4.73e-3)" "unprognostic (2.94e-1)" "unprognostic (3.86e-2)" "unprognostic (6.54e-2)" "unprognostic (1.64e-3)" "unprognostic (4.72e-2)" "unprognostic (1.31e-1)" "unprognostic (9.98e-2)" "unprognostic (2.73e-2)" "unprognostic (8.25e-3)" "unprognostic (8.53e-3)" "unprognostic (8.45e-2)" "unprognostic (1.17e-1)" "unprognostic (8.36e-2)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" 11.2 19.8 9.7 7.5 9.8 1.6 10.6 12.5 10.7 9.7 10.7 15.2 10.5 15.9 9.0 10.3 13.4 8.3 14.0 9.4 10.6 13.5 12.6 11.5 8.0 9.8 10.9 12.8 45.5 18.1 17.1 9.0 10.8 14.9 8.1 7.4 13.0 13.6 26.5 10.1 13.8 10.4 8.5 15.6 11.5 13.5 10.7 3.3 9.5 16.7 5.0 13.5 9.7 9.7 14.1 24.5 7.2 21.9 10.0 3.5 10.2 12.4 26.5 16.9 12.9 13.8 21.5 1.0 17.0 16.8 10.5 7.9 12.1 11.9 6.7 13.6 20.7 8.7 10.5 12.0 15.4 7.5 15.7 9.1 13.9 18.9 10.4 11.2 6.9 0.7 18.1 6.4 10.0 14.7 0.4 8.2 20.5 22.0 16.0 0.4 22.6 26.4 15.9 13.4 11.3 18.3 9.7 30.6 51.6 18.4 26.5 13.1 8.5 11.2 8.9 9.9 15.2 25.6 45.0 0.9 21.5 2.5 15.7 37.4 8.7 18.4 4.5 9.7 5.1 7.4 1.5 4.6 11.4 3.1 0.7 2.0 1.6 20.0 30.2 0.8 2.4 5.2 9.7 9.8 12.5 10.7 9.4 10.6 9.8 10.9 10.8 8.5 10.7 9.7 11.0 16.0 10.8 2.6 3.9 1.7 4.5 4.0 1.8 6.2 6.6 4.1 12.9 15.7 4.7 5.5 0.0 15.9 1.3 5.9 1.9 13.0 2.5 4.5 3.0 10.0 6.0 6.1 4.2 18.0 4.1 5.9 7.7 5.2 14.5 10.1 19.2 8.4 17.2 16.8 4.5 5.1 36.7 7.2 6.5 1.3 7.2 8.2 33.8 5.6 18.9 21.2 2.1 2.5 1.5 15.2 7.8 13.2 9.9 5.3 13.8 7.2 4.9 5.8 6.6 9.4 10.6 1.5 6.1 3.8 1.8 45.8 2.9 6.6 4.3 4.6 PSMA3 HC8 ENSG00000100567 "Proteasome 20S subunit alpha 3" P25788 14 58244843-58272012 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000905 Approved NA NA 9700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "HPA000905: AB_1079702" "unprognostic (3.60e-1)" "unprognostic (4.81e-3)" "unprognostic (1.17e-1)" "unprognostic (2.19e-2)" "unprognostic (4.91e-1)" "unprognostic (5.79e-2)" "unprognostic (1.97e-3)" "unprognostic (1.27e-1)" "unprognostic (7.92e-2)" "unprognostic (7.36e-3)" "unprognostic (1.65e-2)" "unprognostic (7.57e-2)" "unprognostic (1.83e-3)" "unprognostic (2.33e-2)" "unprognostic (6.47e-2)" "prognostic favorable (2.91e-4)" "unprognostic (2.16e-1)" 74.1 88.6 50.0 84.8 52.6 82.8 82.1 54.9 61.8 59.6 54.2 76.7 81.3 55.4 127.6 75.8 57.9 60.7 99.9 51.2 55.2 94.3 162.2 69.0 104.1 53.2 52.3 40.4 55.4 72.9 46.6 90.8 53.3 60.9 82.9 48.3 54.7 76.3 170.6 53.1 74.3 78.6 55.8 66.6 61.0 41.3 51.9 108.6 74.9 130.4 96.9 102.5 48.6 56.6 359.2 214.3 215.1 179.2 166.4 154.3 277.8 187.2 209.3 257.4 256.8 317.8 294.2 304.1 330.9 171.3 202.4 243.9 249.2 200.9 299.7 262.3 148.9 208.5 150.9 360.8 314.2 340.4 170.0 132.8 142.2 179.2 169.1 151.7 307.2 242.0 201.3 174.6 209.3 400.4 299.7 314.4 144.9 286.8 328.3 249.3 279.6 222.7 377.5 339.7 202.9 100.3 167.5 261.8 189.5 201.6 273.3 244.9 198.3 148.4 287.1 167.6 249.4 68.4 137.3 314.1 215.7 260.2 184.1 95.3 78.9 52.0 71.2 98.9 92.2 85.8 87.1 86.0 91.8 61.9 69.5 80.8 48.2 94.1 85.6 122.4 112.6 95.5 50.0 52.6 54.9 61.8 51.2 55.2 53.2 52.3 53.3 55.8 51.9 56.6 132.9 118.6 119.2 21.9 93.7 118.7 169.6 418.7 71.2 43.5 69.2 77.6 117.0 71.4 195.7 88.3 35.5 387.5 104.5 83.3 166.3 241.3 24.7 127.6 95.6 137.7 64.4 60.6 27.6 231.1 269.2 108.5 59.1 109.1 95.7 412.6 66.4 145.4 184.0 42.1 29.1 103.8 250.3 59.2 77.5 27.4 109.3 89.4 108.5 26.2 206.0 87.3 84.5 32.6 33.6 192.9 89.0 106.1 118.4 167.5 108.9 297.5 157.4 68.6 98.6 83.7 279.6 109.3 66.9 89.8 106.0 403.5 99.3 104.9 108.4 171.6 PSMA5 ZETA ENSG00000143106 "Proteasome 20S subunit alpha 5" P28066 1 109399042-109426448 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 54.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028392, HPA028398, HPA028441" Approved Supported Cytosol NA NA 20000000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA028392: AB_10600115, HPA028398: AB_10602310, HPA028441: AB_10602003" "unprognostic (3.82e-2)" "unprognostic (3.09e-3)" "prognostic favorable (1.45e-5)" "unprognostic (1.57e-1)" "unprognostic (2.71e-1)" "unprognostic (1.52e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (5.95e-2)" "unprognostic (1.71e-2)" "unprognostic (1.13e-3)" "unprognostic (4.20e-3)" "unprognostic (3.05e-1)" "unprognostic (1.07e-3)" "unprognostic (3.99e-2)" "unprognostic (2.34e-1)" "unprognostic (8.81e-3)" "unprognostic (1.05e-1)" 3.5 4.7 5.1 4.3 6.2 3.8 6.8 4.0 7.7 5.8 2.7 7.4 7.5 5.5 8.6 6.8 9.1 5.4 7.7 6.8 6.7 10.9 20.2 5.9 12.7 5.0 4.7 5.2 3.2 5.9 1.4 6.9 4.5 5.4 8.5 4.8 5.0 6.2 6.1 6.2 6.7 6.5 4.1 4.8 5.2 3.5 5.3 6.4 10.2 5.1 9.3 6.1 0.9 6.6 10.1 11.7 6.2 5.7 17.6 16.9 12.6 4.9 29.8 23.2 17.9 15.0 5.5 28.1 7.8 21.2 4.2 5.7 13.8 13.7 16.1 10.7 13.1 13.4 7.7 12.4 14.0 15.2 5.3 8.5 12.3 12.7 14.3 6.2 15.0 8.2 17.1 6.5 12.4 18.6 54.4 10.3 5.7 7.0 16.5 4.4 16.9 7.4 19.0 11.5 7.3 5.2 10.5 16.2 8.9 5.0 5.9 14.1 11.7 4.6 4.6 7.9 10.3 3.6 11.6 19.7 20.0 26.0 7.4 11.0 4.3 3.1 7.7 6.3 8.4 5.7 9.0 8.3 5.9 4.7 9.7 9.7 1.4 7.2 6.1 4.2 11.4 7.0 5.1 6.2 4.0 7.7 6.8 6.7 5.0 4.7 4.5 4.1 5.3 6.6 68.9 41.7 56.8 9.4 77.4 63.6 73.5 231.0 38.1 32.6 59.5 75.7 89.5 75.8 120.9 42.3 6.2 227.0 114.5 82.1 140.8 164.9 82.0 157.6 74.1 71.6 56.3 85.0 21.7 183.0 181.4 60.4 74.9 81.9 82.4 77.7 51.4 117.4 166.9 13.5 18.4 144.1 168.9 57.8 73.6 23.4 67.7 86.3 58.7 15.0 184.8 50.2 114.4 13.0 20.2 191.6 103.5 62.1 113.1 122.2 138.0 205.6 172.4 31.7 46.0 56.1 182.6 120.3 89.1 70.4 65.9 241.2 106.1 121.4 135.3 104.2 PSMA7 "C6, HSPC, RC6-1, XAPC7" ENSG00000101182 "Proteasome 20S subunit alpha 7" O14818 20 62136733-62143440 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 753.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046007, CAB046008, HPA047266" Approved NA NA 22000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "CAB046007: AB_11128404, CAB046008: AB_2171861, HPA047266: AB_2680006" "unprognostic (1.49e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-2)" "unprognostic (2.79e-2)" "unprognostic (6.36e-1)" "unprognostic (6.57e-3)" "prognostic unfavorable (2.54e-5)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (5.06e-3)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (7.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.21e-2)" "unprognostic (6.31e-2)" "unprognostic (1.98e-2)" 223.2 200.1 127.6 148.5 132.0 260.4 198.0 136.9 146.2 134.6 127.1 180.3 132.2 163.4 102.9 191.0 140.5 91.3 266.2 131.9 137.0 168.9 214.0 170.3 164.9 134.0 131.7 134.4 140.2 114.1 104.1 115.0 136.7 117.8 108.0 54.5 129.2 104.2 753.9 136.6 151.3 117.1 134.7 163.3 152.9 61.3 136.4 188.0 121.9 375.3 155.4 168.2 141.3 143.7 532.8 674.6 390.9 419.4 357.2 277.8 345.0 398.3 343.6 1024.7 428.8 1785.8 504.0 438.2 926.2 421.0 644.1 627.2 371.9 752.5 497.0 261.0 261.1 1009.7 641.9 913.2 454.0 434.3 570.4 297.9 602.0 525.1 454.5 248.8 509.2 436.1 439.2 419.2 441.8 568.6 696.1 673.6 332.5 595.0 859.8 476.9 753.5 482.6 385.3 515.4 526.2 321.6 625.9 777.1 701.9 252.7 468.3 643.3 416.1 898.9 725.4 473.3 631.1 286.9 483.9 531.2 626.7 327.7 536.1 754.4 682.6 801.5 536.5 692.6 458.2 579.3 533.3 531.4 632.2 522.7 415.1 427.3 582.2 421.7 720.3 676.3 723.4 1131.2 127.6 132.0 136.9 146.2 131.9 137.0 134.0 131.7 136.7 134.7 136.4 143.7 402.9 211.5 180.8 20.9 252.3 374.5 350.6 616.4 167.4 127.5 223.0 296.4 304.9 327.5 369.2 257.5 73.0 666.2 309.5 375.2 498.9 581.9 355.5 290.2 345.4 397.3 232.0 439.4 19.2 727.7 775.7 321.9 132.0 276.5 251.4 304.7 335.5 787.5 807.0 82.4 18.4 325.6 453.7 435.7 453.1 211.0 334.6 414.8 368.2 18.7 598.4 219.3 377.9 15.1 28.9 663.3 386.4 293.8 234.5 639.7 455.1 759.6 288.8 122.5 230.1 237.0 659.7 81.4 126.3 291.9 309.3 852.6 310.4 410.0 386.9 438.7 PSMB1 "HC5, PMSB1" ENSG00000008018 "Proteasome 20S subunit beta 1" P20618 6 170535120-170553307 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1197.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029635, HPA029637, CAB033911" Enhanced Supported Nucleoplasm NA NA 15000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB033911: AB_2268890, HPA029635: AB_10599738, HPA029637: AB_10601793" "unprognostic (2.78e-2)" "unprognostic (3.10e-2)" "unprognostic (6.73e-2)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (5.41e-3)" "unprognostic (2.36e-2)" "unprognostic (3.32e-2)" "unprognostic (8.39e-2)" "unprognostic (4.28e-2)" "unprognostic (3.07e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.76e-6)" "unprognostic (3.63e-1)" "unprognostic (7.50e-2)" "unprognostic (1.45e-3)" "unprognostic (9.62e-2)" 214.3 191.2 127.8 138.1 131.9 206.8 186.4 129.8 150.7 146.1 131.9 175.9 147.4 174.9 279.4 175.2 157.1 114.5 222.3 127.7 139.0 179.7 308.6 158.3 175.8 129.2 127.5 136.6 153.1 169.2 151.8 173.8 133.2 130.9 166.9 98.5 141.7 151.3 355.2 192.2 149.1 164.3 137.6 165.7 156.8 114.3 132.9 180.5 142.4 239.2 206.8 168.8 143.4 143.0 309.8 284.9 396.2 514.9 347.3 271.2 421.6 288.3 422.7 471.6 478.5 628.9 259.3 449.1 366.2 390.0 430.8 303.7 446.0 459.8 488.7 460.2 502.1 384.4 277.6 799.6 406.3 455.8 327.1 311.5 277.6 455.6 293.1 322.4 409.9 278.1 774.3 373.2 436.9 835.1 343.5 633.0 362.7 558.1 387.9 326.9 314.1 571.6 495.1 183.6 394.5 321.6 277.1 424.5 231.5 351.1 290.9 648.4 313.3 190.4 304.8 466.9 543.2 315.8 454.8 565.8 443.7 510.9 417.5 258.4 431.9 290.2 265.2 416.1 313.5 386.4 306.0 290.7 523.1 305.7 288.1 279.8 249.3 408.2 384.4 297.4 442.6 652.5 127.8 131.9 129.8 150.7 127.7 139.0 129.2 127.5 133.2 137.6 132.9 143.0 242.7 112.2 148.5 19.9 182.1 217.2 351.4 750.7 117.8 120.2 168.2 236.3 232.3 208.8 335.5 141.6 41.7 876.6 175.0 222.0 401.1 498.3 332.4 224.6 190.2 243.8 165.3 223.9 23.5 651.4 790.8 245.5 109.6 215.1 189.5 226.1 168.8 349.8 394.3 119.5 25.1 251.6 417.1 165.3 222.3 81.9 256.3 207.3 231.3 20.6 364.5 237.8 206.0 19.6 43.3 525.5 240.1 235.9 253.4 334.9 327.6 537.0 310.0 135.9 190.7 181.2 500.2 247.8 196.3 153.3 215.8 1197.8 182.1 283.7 276.7 365.4 PSMB2 HC7-I ENSG00000126067 "Proteasome 20S subunit beta 2" P49721 1 35599541-35641526 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026322, HPA026324" Approved Enhanced Nucleoplasm NA NA 9700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA026322: AB_1855821, HPA026324: AB_1855822" "unprognostic (3.54e-2)" "unprognostic (8.53e-2)" "unprognostic (1.63e-3)" "unprognostic (6.93e-2)" "unprognostic (6.41e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.49e-7)" "unprognostic (2.81e-2)" "unprognostic (5.23e-2)" "unprognostic (3.34e-3)" "unprognostic (7.87e-2)" "unprognostic (4.45e-1)" "prognostic unfavorable (2.80e-6)" "unprognostic (1.65e-1)" "unprognostic (2.83e-1)" "unprognostic (3.77e-2)" "unprognostic (2.93e-2)" 26.4 29.3 10.0 13.9 10.3 21.7 25.0 9.7 11.6 23.6 9.4 24.3 12.9 26.9 11.5 31.8 21.9 9.1 27.3 10.6 10.4 22.6 45.9 25.6 15.8 9.9 9.7 21.0 25.2 11.3 19.6 15.2 11.0 20.0 12.7 12.1 22.3 10.8 63.1 30.9 23.2 13.4 9.9 25.4 24.2 15.6 9.5 20.5 18.7 14.8 16.7 22.9 23.9 11.8 68.8 42.4 45.5 32.2 23.3 27.9 55.5 31.8 36.6 63.2 51.1 51.6 79.3 68.8 71.3 37.6 38.6 41.2 59.3 53.4 54.5 54.5 54.1 63.4 44.5 50.1 41.4 66.1 34.7 30.4 33.4 77.0 36.8 25.9 50.8 54.1 76.6 37.7 41.9 30.7 85.5 50.1 59.3 29.7 44.0 52.3 47.5 48.7 45.3 35.9 39.8 30.1 36.0 34.5 52.1 50.3 24.9 29.3 35.2 32.0 37.5 30.9 76.5 31.8 55.0 66.9 49.9 70.4 55.6 20.5 23.6 18.2 19.6 30.3 19.9 22.3 19.3 20.6 26.4 18.5 14.0 17.3 8.8 23.6 35.4 27.4 26.3 26.1 10.0 10.3 9.7 11.6 10.6 10.4 9.9 9.7 11.0 9.9 9.5 11.8 110.8 64.1 68.9 6.2 80.4 111.1 145.2 298.5 50.7 48.0 65.8 95.1 59.8 67.2 145.0 66.2 16.7 406.6 83.6 72.4 144.8 286.2 118.0 95.4 78.8 115.9 98.3 78.7 20.8 227.3 341.0 101.3 61.2 75.9 35.4 109.6 85.6 158.1 222.6 58.9 20.9 96.9 187.2 92.7 70.3 22.8 100.6 94.1 76.5 15.9 184.1 68.4 87.6 17.1 23.4 252.0 76.6 91.4 141.7 186.0 108.5 221.7 126.8 50.4 92.1 66.8 291.4 224.4 144.0 80.4 111.5 442.1 81.4 123.9 111.7 178.9 PSMB3 "HC10-II, MGC4147" ENSG00000277791 "Proteasome 20S subunit beta 3" P49720 17 38752741-38764225 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042775, HPA048147" Approved NA NA 25000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA042775: AB_2678158, HPA048147: AB_2680285" "unprognostic (1.86e-1)" "unprognostic (4.84e-3)" "unprognostic (1.44e-1)" "unprognostic (4.80e-2)" "unprognostic (6.68e-2)" "unprognostic (1.14e-3)" "unprognostic (5.46e-2)" "unprognostic (2.46e-2)" "unprognostic (2.02e-1)" "unprognostic (1.75e-2)" "unprognostic (3.65e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.71e-6)" "unprognostic (4.44e-1)" "unprognostic (1.28e-1)" "unprognostic (2.42e-3)" "unprognostic (6.03e-2)" 95.7 139.3 65.9 95.7 70.8 138.7 92.9 68.2 76.1 83.0 67.4 105.6 82.5 90.6 101.8 110.9 81.4 73.0 154.2 74.4 80.3 120.7 187.3 101.8 137.0 70.0 73.2 59.3 78.1 86.2 81.4 90.9 70.6 85.6 106.1 42.4 84.1 66.6 201.7 99.0 90.3 92.7 69.4 122.0 93.8 53.2 76.1 106.3 87.6 119.5 132.5 102.8 83.0 80.1 246.1 457.3 168.8 277.2 180.9 158.6 237.1 167.6 265.8 563.8 489.1 486.3 324.1 279.5 276.3 228.8 371.1 401.6 279.3 294.3 301.1 373.6 500.2 184.2 226.6 562.5 96.5 289.3 278.1 151.0 184.6 393.5 131.1 132.9 289.3 283.1 301.2 320.4 246.2 319.6 461.1 457.0 250.6 278.8 328.3 261.1 383.3 446.2 312.1 253.4 216.8 145.7 191.8 157.3 201.3 243.8 360.1 356.6 173.1 138.0 269.5 308.9 421.1 202.1 367.2 397.7 285.2 294.8 242.0 227.2 323.7 150.4 176.6 271.4 118.1 148.5 145.2 154.4 274.5 114.6 93.0 94.9 569.6 142.8 209.6 352.6 176.1 372.0 65.9 70.8 68.2 76.1 74.4 80.3 70.0 73.2 70.6 69.4 76.1 80.1 146.2 76.9 124.5 8.8 142.0 199.6 203.6 517.8 79.1 66.7 100.9 105.8 328.0 104.4 281.6 176.6 25.0 434.0 141.4 215.0 406.9 362.1 51.5 140.6 123.8 185.5 133.4 156.4 8.6 497.7 428.3 160.8 100.9 117.7 154.0 110.0 118.9 247.6 416.7 30.3 7.8 207.1 368.2 161.5 266.5 48.2 149.5 231.8 200.9 7.5 309.8 167.5 179.2 3.0 12.6 401.0 242.9 145.9 205.1 189.9 219.9 642.6 274.9 72.2 124.9 110.2 507.6 152.2 76.7 114.0 201.5 504.2 154.0 186.7 224.7 239.9 PSMB4 "HN3, PROS26" ENSG00000159377 "Proteasome 20S subunit beta 4" P28070 1 151399560-151401937 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006700, HPA073499" Approved Uncertain Nucleoplasm,Mitochondria NA NA 12000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Mitochondria "HPA006700: AB_1079704, HPA073499: " "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" "unprognostic (2.69e-1)" "unprognostic (2.52e-1)" "unprognostic (1.63e-1)" "unprognostic (5.74e-2)" "prognostic unfavorable (7.45e-4)" "unprognostic (2.27e-1)" "unprognostic (1.69e-1)" "unprognostic (4.37e-3)" "unprognostic (3.73e-1)" "unprognostic (3.77e-1)" "prognostic unfavorable (2.90e-10)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (3.82e-2)" "unprognostic (5.85e-2)" 189.5 242.7 200.2 156.7 202.1 172.9 174.2 210.6 212.4 167.0 201.9 194.3 150.0 195.5 225.6 170.4 178.3 139.1 241.8 201.7 212.9 196.6 269.5 143.2 214.0 206.8 203.9 179.5 164.0 218.6 168.0 187.1 211.7 162.4 166.4 94.3 169.6 190.6 299.1 186.6 152.8 191.7 210.5 173.8 171.8 69.0 205.8 233.5 156.1 237.5 235.4 196.7 151.3 218.4 428.3 451.9 373.0 447.8 412.9 392.3 507.8 247.6 549.2 719.3 503.1 608.6 569.5 384.1 730.7 424.3 379.1 419.7 383.2 472.7 407.6 535.6 391.1 268.6 320.8 463.3 444.4 377.0 355.7 431.7 444.8 672.5 276.2 364.8 506.1 419.1 434.3 740.0 512.7 1174.2 463.5 452.0 952.8 638.6 576.2 433.8 266.9 688.2 594.4 354.2 408.6 488.0 283.6 626.5 879.8 459.1 564.1 594.6 320.7 310.4 326.1 333.8 557.0 726.9 902.5 769.1 459.5 337.8 667.8 291.8 343.4 227.0 265.0 342.2 314.8 293.6 303.7 301.0 421.7 257.5 260.4 272.8 251.5 347.3 270.5 468.1 405.1 395.2 200.2 202.1 210.6 212.4 201.7 212.9 206.8 203.9 211.7 210.5 205.8 218.4 72.2 153.8 127.4 10.1 82.2 76.6 81.9 131.5 82.0 56.3 62.0 71.6 128.0 68.6 123.2 71.7 16.7 209.8 79.7 87.8 103.7 127.9 16.0 118.1 107.5 97.7 66.4 87.1 10.4 195.8 146.7 91.9 47.4 110.0 111.1 81.1 92.8 151.7 125.0 48.8 11.5 80.5 89.5 108.1 88.8 15.6 104.4 89.4 96.0 12.2 186.2 89.5 64.9 6.6 14.7 131.7 75.0 105.3 89.1 75.5 117.5 148.9 141.5 62.8 65.7 86.0 127.5 54.5 49.7 80.0 75.9 267.3 80.2 124.5 96.0 89.1 PSMB5 MB1 ENSG00000100804 "Proteasome 20S subunit beta 5" P28074 14 23016543-23035230 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 1146.8" "Low region specificity" "Detected in all" "HPA049518, HPA061796" Approved Supported Nucleoplasm,Centrosome NA NA 6200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Centrosome" "HPA049518: AB_2680802, HPA061796: AB_2684612" "unprognostic (3.03e-1)" "unprognostic (1.99e-2)" "unprognostic (8.35e-2)" "unprognostic (6.13e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.85e-4)" "prognostic unfavorable (2.90e-5)" "unprognostic (2.55e-2)" "unprognostic (9.95e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.06e-1)" "unprognostic (1.19e-1)" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (1.95e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (4.73e-4)" 84.0 116.0 129.1 58.7 134.2 32.0 81.0 141.4 134.3 71.3 141.1 80.8 61.1 71.0 129.5 102.3 93.3 61.0 136.8 136.4 141.1 98.5 119.1 64.7 49.0 137.9 138.4 61.6 80.9 143.5 80.1 90.1 145.2 76.8 88.7 59.7 73.5 78.6 332.4 76.0 53.0 103.4 141.3 50.3 81.0 57.8 136.5 79.5 72.3 274.1 68.6 92.1 68.4 146.5 181.0 398.9 250.6 245.5 360.4 318.9 261.8 252.0 307.3 446.1 376.1 329.2 282.2 228.0 228.1 352.1 298.4 239.7 428.4 320.2 401.9 139.9 311.4 146.9 260.3 1146.8 287.3 170.2 162.1 354.2 292.0 331.8 264.1 289.7 475.5 190.5 218.6 121.5 376.0 557.2 97.6 218.4 285.7 341.6 631.4 133.8 197.7 150.7 349.9 256.6 336.0 251.0 179.9 354.8 245.4 322.2 175.0 217.7 254.1 212.4 210.1 197.3 247.8 99.7 218.4 158.8 164.9 140.8 274.6 97.8 127.6 58.0 89.4 125.6 103.5 103.8 101.1 85.1 137.6 99.7 135.0 102.5 48.1 67.4 92.7 172.4 91.3 147.8 129.1 134.2 141.4 134.3 136.4 141.1 137.9 138.4 145.2 141.3 136.5 146.5 94.2 76.9 69.2 16.0 47.3 140.2 174.1 461.5 100.7 61.0 130.4 135.5 157.6 112.9 240.4 95.6 29.2 400.1 40.2 75.0 275.9 277.7 93.0 149.0 109.5 150.0 154.6 82.5 17.6 231.3 435.2 139.9 73.9 88.0 31.0 162.6 89.6 171.6 221.6 70.7 18.0 109.2 329.6 57.5 80.9 106.4 118.7 64.0 115.6 15.9 138.2 170.8 25.7 11.6 29.4 285.7 88.0 122.2 78.2 185.1 81.2 437.8 268.9 71.8 98.6 87.1 355.1 174.4 81.6 144.7 157.1 430.2 43.4 215.7 148.9 215.3 PSMB6 "DELTA, Y" ENSG00000142507 "Proteasome 20S subunit beta 6" P28072 17 4796144-4798502 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023312, HPA063656" Supported Supported Nucleoplasm,Cytosol NA NA 1400000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA023312: AB_1855828, HPA063656: AB_2685078" "unprognostic (2.71e-1)" "unprognostic (1.86e-2)" "unprognostic (2.75e-1)" "unprognostic (3.32e-3)" "unprognostic (8.80e-2)" "unprognostic (1.44e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-2)" "unprognostic (7.47e-2)" "prognostic unfavorable (5.93e-4)" "unprognostic (1.81e-1)" "unprognostic (2.34e-1)" "unprognostic (5.27e-2)" "unprognostic (5.66e-2)" 92.7 107.8 130.1 82.2 133.7 126.9 107.0 138.1 141.2 92.6 137.4 116.3 76.9 101.9 150.9 140.6 99.2 68.3 201.6 132.8 138.1 134.8 184.6 86.2 90.1 135.7 134.1 63.7 99.3 173.3 82.5 119.8 138.7 84.8 118.3 62.6 100.0 114.2 358.6 114.9 77.0 135.3 136.0 90.4 103.8 76.6 133.5 147.4 88.7 339.5 140.5 110.6 89.2 140.3 279.8 478.2 251.6 216.4 209.9 188.1 289.7 144.1 300.1 431.3 336.0 358.7 220.5 215.0 277.9 348.1 246.5 273.8 388.0 404.4 418.0 281.9 409.7 128.0 315.3 422.7 242.0 133.5 194.4 178.3 305.1 377.4 355.7 241.5 426.5 335.8 199.4 316.6 336.1 331.8 237.4 221.8 214.1 356.2 328.2 261.9 178.7 284.6 326.6 185.3 146.9 179.9 206.6 158.9 148.6 261.4 194.5 147.2 205.1 210.8 158.9 286.4 355.2 130.8 191.8 132.9 301.3 242.1 259.3 410.6 603.3 343.2 347.5 589.9 355.9 668.6 373.1 384.0 624.9 640.8 319.8 329.3 210.5 424.4 549.4 585.5 556.2 817.2 130.1 133.7 138.1 141.2 132.8 138.1 135.7 134.1 138.7 136.0 133.5 140.3 156.3 134.6 113.3 8.5 118.3 229.2 184.1 410.8 112.1 65.5 124.6 153.4 454.8 141.5 253.9 134.3 16.7 587.3 142.8 178.0 358.1 321.6 245.2 110.9 108.1 164.7 148.4 183.7 7.6 349.9 418.2 171.5 105.5 116.0 105.2 156.1 99.6 235.4 346.3 32.0 7.2 173.0 311.3 111.7 272.1 52.9 109.6 159.8 236.5 4.7 298.9 183.4 109.2 9.0 16.9 351.3 163.4 123.0 244.7 191.7 188.6 564.6 193.3 81.3 111.7 119.8 486.8 175.1 84.7 178.6 277.2 664.5 125.9 172.6 177.7 217.3 PSMB7 Z ENSG00000136930 "Proteasome 20S subunit beta 7" Q99436 9 124353465-124415444 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052408, HPA054902" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No No 2100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA052408: AB_2681820, HPA054902: AB_2682635" "unprognostic (7.75e-2)" "unprognostic (1.83e-2)" "unprognostic (1.27e-1)" "unprognostic (3.64e-3)" "unprognostic (2.83e-1)" "unprognostic (1.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.24e-3)" "unprognostic (9.03e-2)" "unprognostic (3.60e-1)" "unprognostic (2.99e-1)" "unprognostic (1.78e-1)" "unprognostic (1.26e-2)" "unprognostic (1.67e-1)" "unprognostic (3.45e-1)" "unprognostic (1.93e-3)" "unprognostic (3.98e-2)" 115.7 180.4 129.4 103.9 136.9 189.7 122.6 132.7 144.8 99.8 119.6 103.5 98.7 102.9 147.0 139.1 94.6 87.2 212.0 135.8 137.0 150.9 222.9 91.4 112.7 138.2 139.5 101.6 142.2 143.4 74.7 120.2 138.2 94.8 107.8 81.0 114.3 75.0 277.8 166.2 98.3 92.7 131.5 91.7 115.3 155.2 137.8 147.6 91.3 205.3 124.6 110.5 104.2 135.0 344.4 411.7 275.8 336.4 190.4 224.8 396.1 325.3 447.6 461.7 315.1 546.3 327.1 389.2 256.8 307.4 457.2 480.2 346.7 345.4 420.0 375.0 299.3 245.3 673.3 460.0 428.5 491.6 234.3 270.8 299.6 483.7 478.5 355.1 394.3 345.5 507.9 269.8 362.4 600.0 355.9 329.5 409.7 519.6 581.5 309.8 411.4 457.2 331.5 221.9 323.7 263.6 310.4 394.0 498.4 268.7 454.8 212.7 315.9 297.5 240.7 384.9 499.0 289.9 873.7 394.9 498.1 297.8 429.1 162.7 201.5 154.5 128.3 211.4 138.9 177.8 145.7 142.5 221.1 159.7 138.2 135.9 87.0 185.3 206.8 187.5 226.0 264.8 129.4 136.9 132.7 144.8 135.8 137.0 138.2 139.5 138.2 131.5 137.8 135.0 73.1 76.9 77.6 26.1 88.0 194.1 184.4 309.1 39.9 41.5 113.9 97.5 147.3 134.4 150.0 69.9 22.9 441.4 83.0 146.9 330.6 351.3 404.6 105.7 93.8 123.8 141.2 93.8 38.4 392.7 356.7 112.3 52.5 90.3 104.6 130.8 107.1 277.3 237.2 33.7 31.9 162.5 160.7 122.1 148.4 472.8 139.1 92.5 199.3 33.7 168.5 119.7 113.3 30.7 44.8 393.6 143.7 125.3 69.9 158.0 173.6 484.7 135.7 61.6 85.5 133.8 221.2 330.6 190.4 60.4 218.9 488.7 81.4 135.8 181.2 201.3 PSMC1 "p56, S4" ENSG00000100764 "Proteasome 26S subunit, ATPase 1" P62191 14 90256527-90275429 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 308.0" "Cell type enhanced" "Detected in all" "Early spermatids: 593.2;Late spermatids: 549.5;Syncytiotrophoblasts: 469.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000872, HPA016885" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 110000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA000872: AB_1079705, HPA016885: " "unprognostic (4.10e-1)" "unprognostic (9.70e-2)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (1.23e-2)" "unprognostic (1.00e-2)" "unprognostic (1.58e-1)" "unprognostic (1.03e-3)" "unprognostic (1.12e-2)" "unprognostic (1.10e-2)" "unprognostic (1.14e-2)" "unprognostic (1.28e-1)" "unprognostic (1.03e-1)" "unprognostic (2.85e-1)" "unprognostic (1.11e-2)" 76.7 61.3 47.6 48.0 50.3 86.3 64.9 50.8 63.3 51.7 47.6 72.4 35.7 67.3 71.6 71.5 53.4 37.5 114.9 49.5 53.6 62.2 83.3 55.0 49.5 50.5 51.3 45.6 52.7 69.3 37.0 69.6 53.0 49.7 60.4 40.1 55.3 57.5 308.0 74.1 54.5 61.5 49.4 57.5 61.1 82.2 50.3 62.5 48.1 142.5 72.2 64.7 54.1 50.8 141.6 131.1 147.5 154.8 126.6 115.4 154.9 133.5 185.7 287.9 215.4 122.3 154.7 119.4 198.4 162.3 132.2 142.8 182.2 155.8 334.2 143.9 80.0 93.8 84.6 105.9 109.1 143.7 120.4 104.3 120.7 187.9 137.1 120.2 176.2 130.3 134.8 69.9 200.6 267.9 108.0 186.7 130.6 180.7 160.4 127.5 190.8 97.6 163.0 144.6 154.6 103.2 109.0 279.6 118.0 121.8 175.9 125.2 134.9 110.1 98.8 119.6 196.3 120.0 204.3 178.3 159.8 129.1 172.1 95.1 101.4 160.1 67.1 93.7 66.4 57.7 68.5 69.0 101.1 56.8 62.5 60.7 109.9 82.0 110.7 70.8 101.2 116.5 47.6 50.3 50.8 63.3 49.5 53.6 50.5 51.3 53.0 49.4 50.3 50.8 63.1 102.5 80.4 11.4 51.4 65.0 90.3 175.3 30.1 51.3 48.6 45.7 39.2 88.6 136.0 55.2 52.1 304.2 48.2 91.2 119.3 180.8 593.2 68.9 56.1 90.1 57.0 80.6 21.0 197.7 178.9 71.4 30.1 70.1 98.2 82.4 75.7 196.6 150.2 79.1 21.2 68.7 111.9 91.8 82.2 549.5 76.4 74.7 67.6 14.0 146.0 88.1 72.1 10.6 22.3 210.3 71.5 82.0 50.7 75.5 104.2 160.4 123.9 65.8 85.5 67.5 139.5 198.1 48.7 44.1 50.2 469.4 55.4 82.5 74.4 92.7 PSMC2 "MSS1, Nbla10058, S7" ENSG00000161057 "Proteasome 26S subunit, ATPase 2" P35998 7 103328570-103370346 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 231.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019238, HPA049621" Supported Supported "Cytosol,Cytoplasmic bodies" NA NA 190000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Cytosol, Cytoplasmic bodies" "HPA019238: AB_1855834, HPA049621: AB_2680833" "unprognostic (4.00e-2)" "unprognostic (6.66e-2)" "unprognostic (2.55e-1)" "unprognostic (3.58e-1)" "unprognostic (1.57e-3)" "unprognostic (3.55e-2)" "unprognostic (2.08e-2)" "unprognostic (6.08e-2)" "unprognostic (7.73e-2)" "unprognostic (1.49e-2)" "unprognostic (1.07e-1)" "unprognostic (4.71e-1)" "unprognostic (5.09e-3)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (9.76e-2)" "unprognostic (1.41e-1)" 34.1 33.6 19.6 31.7 21.6 32.0 25.6 23.7 29.5 26.2 24.3 26.2 25.2 23.5 27.8 27.2 23.1 22.0 35.9 20.5 22.9 39.9 54.2 23.5 29.6 22.5 21.0 21.2 16.5 41.4 16.1 30.9 22.3 27.1 22.8 22.3 23.8 26.4 87.2 27.6 24.5 29.6 24.3 22.4 29.5 25.8 21.7 42.4 29.2 77.1 33.5 34.3 17.7 24.8 133.5 78.3 84.4 98.2 93.0 69.7 58.5 102.5 97.9 123.7 122.7 92.7 97.3 100.1 199.2 94.7 168.1 71.0 109.2 76.6 128.7 153.3 68.0 90.5 57.9 57.8 65.2 149.0 84.9 55.3 50.2 122.5 38.9 60.9 89.8 70.4 190.1 98.2 104.2 135.8 165.0 74.2 98.7 109.6 95.2 73.8 108.4 93.8 80.6 64.2 65.3 64.9 97.6 123.9 89.6 92.9 56.6 73.3 91.5 80.9 106.6 174.6 153.8 98.9 274.8 191.3 118.1 143.7 138.5 140.0 53.4 52.7 44.7 81.6 51.5 47.5 51.1 47.9 75.3 40.6 46.3 47.3 7.3 58.4 98.2 42.3 93.3 74.2 19.6 21.6 23.7 29.5 20.5 22.9 22.5 21.0 22.3 24.3 21.7 24.8 36.2 48.1 29.5 18.3 33.8 39.8 41.4 131.8 24.5 36.0 23.5 27.2 61.8 40.0 73.9 27.6 14.6 172.2 34.4 22.5 66.5 113.9 118.9 32.3 33.9 48.5 8.4 64.6 27.9 96.4 110.6 49.7 27.5 24.9 56.4 35.5 34.2 48.5 134.6 26.9 25.1 36.9 93.6 48.5 40.4 33.2 58.4 46.1 32.0 15.9 62.4 69.5 40.2 21.1 32.8 87.3 38.5 64.3 45.0 34.7 36.9 88.8 52.5 49.1 59.2 43.7 105.2 96.3 47.2 23.6 42.9 231.8 39.5 49.1 32.0 42.9 PSMC3 "TBP-1, TBP1" ENSG00000165916 "Proteasome 26S subunit, ATPase 3" P17980 11 47418769-47426473 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006065 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 290000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA006065: AB_1079706" "unprognostic (2.01e-2)" "unprognostic (5.08e-3)" "unprognostic (9.43e-2)" "unprognostic (8.12e-3)" "unprognostic (6.32e-2)" "unprognostic (5.71e-2)" "unprognostic (8.99e-3)" "unprognostic (1.63e-1)" "unprognostic (9.95e-2)" "unprognostic (1.27e-2)" "unprognostic (3.88e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (1.49e-1)" "unprognostic (2.25e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" 85.3 86.1 106.8 64.7 117.3 96.1 77.9 105.3 131.0 73.7 105.8 110.2 52.2 89.9 62.5 88.7 69.0 44.0 172.1 107.8 106.3 73.8 117.7 76.2 65.3 108.6 114.7 58.2 81.4 74.1 55.4 78.8 111.0 74.2 59.1 30.9 73.0 69.8 292.0 103.4 64.0 77.5 104.6 67.8 87.7 74.7 115.2 90.6 69.4 162.9 76.5 80.8 71.7 107.0 223.7 248.2 233.5 173.3 109.6 117.3 226.5 181.5 267.4 445.7 313.8 223.3 126.8 179.5 110.1 230.1 195.7 218.3 206.7 237.7 199.0 269.4 268.1 173.1 301.1 218.5 141.4 203.7 177.0 131.4 126.1 181.6 202.5 98.4 253.8 182.7 249.2 164.7 276.0 497.0 259.5 258.4 229.5 280.7 296.1 269.3 458.8 157.3 209.5 165.2 170.0 147.1 148.7 206.9 116.2 98.2 255.7 209.8 181.3 253.7 321.1 363.8 474.7 176.5 220.0 209.2 262.4 201.7 325.1 111.5 154.3 121.8 160.8 194.6 146.7 146.8 132.9 147.8 160.6 122.4 116.5 118.6 33.9 173.3 211.6 160.0 191.0 254.7 106.8 117.3 105.3 131.0 107.8 106.3 108.6 114.7 111.0 104.6 115.2 107.0 81.5 57.7 42.0 3.9 59.5 86.3 112.8 198.5 50.7 41.2 61.4 64.1 217.6 81.5 103.7 68.0 16.7 265.9 60.0 143.9 152.6 199.2 152.5 72.0 75.7 96.0 64.5 136.6 6.4 202.6 257.9 100.4 54.0 70.1 75.3 79.2 77.1 144.2 158.2 37.0 5.3 111.5 75.3 62.4 80.0 217.6 88.6 62.5 99.6 1.9 132.0 120.2 74.2 3.0 5.2 214.2 110.8 100.1 96.3 102.8 127.7 191.3 76.9 47.4 118.3 75.1 193.3 147.0 63.6 51.3 77.3 352.9 61.8 74.1 117.6 101.6 PSMC4 "MGC13687, MGC23214, MGC8570, MIP224, S6, TBP-7, TBP7" ENSG00000013275 "Proteasome 26S subunit, ATPase 4" P43686 19 39971165-39981764 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 399.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002044, HPA005471" Approved Supported Nucleoplasm,Cytosol NA NA 200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA002044: AB_1079707, HPA005471: AB_1855838" "unprognostic (1.66e-1)" "unprognostic (9.08e-2)" "unprognostic (1.69e-1)" "unprognostic (1.83e-2)" "unprognostic (7.46e-2)" "unprognostic (2.27e-2)" "unprognostic (1.29e-3)" "unprognostic (1.53e-2)" "unprognostic (4.45e-1)" "unprognostic (4.42e-2)" "unprognostic (9.90e-2)" "unprognostic (8.45e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-1)" "unprognostic (2.02e-1)" "unprognostic (2.81e-1)" "unprognostic (2.32e-1)" 41.3 54.8 21.8 21.0 22.5 14.5 38.2 24.1 24.8 38.0 21.3 41.6 20.4 50.9 26.9 54.8 38.2 16.7 58.9 22.9 25.4 48.4 69.1 35.9 18.2 24.1 23.5 32.0 32.5 30.9 37.1 19.3 25.8 35.2 19.0 13.8 36.5 20.3 112.7 48.1 39.0 20.8 24.6 40.3 43.6 43.2 22.7 22.3 41.1 30.2 23.1 41.6 38.0 26.1 68.7 221.3 43.8 53.5 38.0 31.3 47.0 38.6 50.4 87.0 66.4 129.0 46.8 33.0 72.7 49.2 50.5 35.6 61.6 52.7 72.1 60.6 63.0 46.9 39.2 110.4 52.5 52.2 54.7 31.3 46.0 69.1 48.6 25.8 60.5 42.3 63.0 48.5 57.2 108.3 62.4 32.1 80.5 88.3 66.8 54.6 49.7 48.2 64.3 105.7 56.9 74.8 42.3 69.3 38.9 41.9 47.8 45.5 36.2 53.2 54.9 52.2 97.1 62.2 114.6 51.9 69.7 54.0 62.8 38.0 41.5 33.5 44.8 64.8 39.0 35.8 39.8 46.6 66.9 34.7 32.6 32.8 22.3 43.8 89.8 34.8 59.8 61.9 21.8 22.5 24.1 24.8 22.9 25.4 24.1 23.5 25.8 24.6 22.7 26.1 52.5 32.1 19.8 8.1 53.6 64.0 84.8 191.9 40.9 50.1 31.2 31.9 38.1 52.9 96.2 44.1 14.6 174.7 53.7 119.7 92.0 143.3 203.9 70.3 46.3 63.2 59.2 48.8 8.5 110.9 118.9 55.8 53.5 57.1 41.2 41.9 29.6 50.9 163.7 42.1 8.5 41.7 126.1 42.7 66.3 120.0 55.0 57.4 44.4 12.2 91.6 59.5 63.8 6.6 10.7 127.0 103.1 70.0 58.3 65.4 95.2 179.2 88.0 49.9 92.1 49.0 152.1 114.6 45.7 44.7 58.2 399.5 57.5 69.5 69.1 79.8 PSMC5 "p45, p45/SUG, S8, SUG-1, SUG1, TBP10, TRIP1" ENSG00000087191 "Proteasome 26S subunit, ATPase 5" P62195 17 63827152-63832026 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 596.6;Late spermatids: 1350.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017871, HPA064293" Enhanced Supported "Plasma membrane,Cytosol" NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA017871: AB_1857638, HPA064293: AB_2685234" "unprognostic (9.65e-2)" "unprognostic (1.63e-2)" "unprognostic (4.44e-1)" "unprognostic (2.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.35e-1)" "unprognostic (8.29e-3)" "unprognostic (1.24e-2)" "unprognostic (3.38e-1)" "unprognostic (2.85e-1)" "unprognostic (2.17e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (3.13e-6)" "unprognostic (9.54e-2)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.32e-1)" 90.4 99.0 134.8 80.9 137.5 82.4 80.6 141.3 159.0 79.6 130.2 106.1 68.0 80.1 112.3 104.9 83.2 59.4 107.5 136.2 139.3 120.9 112.7 68.1 93.0 140.5 140.2 63.3 71.0 161.1 82.5 75.5 141.2 81.4 84.4 85.3 73.4 86.7 236.2 121.5 70.6 90.3 137.7 82.4 84.5 73.3 139.6 93.3 86.4 168.7 108.0 93.4 79.6 138.9 240.1 369.1 233.9 172.9 171.4 174.7 202.8 225.3 197.0 327.1 243.8 390.3 154.7 158.7 154.7 241.6 246.0 182.8 239.1 228.5 383.5 136.8 289.7 330.3 288.9 362.4 180.1 336.0 230.4 177.5 171.4 291.9 266.6 139.1 263.7 180.9 258.4 210.2 284.9 450.7 279.4 237.4 215.6 266.3 330.0 248.9 445.5 244.3 249.0 270.9 203.2 274.1 158.6 313.9 152.3 254.4 306.8 197.8 238.8 360.3 329.9 161.5 482.6 220.5 335.2 250.4 225.8 255.7 241.5 105.1 120.4 149.4 164.1 176.3 222.8 142.7 191.6 179.3 140.0 122.0 161.3 183.1 37.7 167.4 206.3 108.6 272.1 216.1 134.8 137.5 141.3 159.0 136.2 139.3 140.5 140.2 141.2 137.7 139.6 138.9 97.9 51.3 78.6 8.5 82.7 94.6 145.0 206.3 71.7 84.9 71.1 79.1 156.0 110.1 139.6 68.0 18.8 250.4 85.1 98.8 246.5 195.2 596.6 75.4 69.4 104.7 90.9 107.7 7.9 214.5 187.2 101.4 69.3 68.1 90.2 53.3 86.4 130.9 162.9 72.3 7.9 92.7 197.4 89.8 85.0 1350.2 133.0 93.4 99.6 5.6 148.0 221.4 109.2 7.5 10.5 167.5 96.3 153.4 88.0 125.6 163.7 330.3 95.1 108.4 111.7 113.0 228.7 151.6 150.2 95.0 102.9 369.0 102.9 124.7 97.9 137.9 PSMC6 p42 ENSG00000100519 "Proteasome 26S subunit, ATPase 6" P62333 14 52707178-52728590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042823 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042823: AB_2678188" "unprognostic (2.38e-2)" "unprognostic (2.72e-2)" "unprognostic (9.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.19e-2)" "unprognostic (4.26e-3)" "unprognostic (3.14e-3)" "unprognostic (6.30e-2)" "unprognostic (1.06e-1)" "unprognostic (2.79e-2)" "unprognostic (3.50e-2)" "unprognostic (1.00e-2)" "unprognostic (1.52e-2)" "unprognostic (5.00e-2)" "unprognostic (2.68e-1)" "unprognostic (4.13e-2)" "unprognostic (4.67e-1)" 43.4 48.4 38.8 47.3 39.2 44.1 58.1 41.2 54.0 44.0 37.4 52.2 50.0 47.6 49.2 65.1 49.2 36.5 78.7 39.8 42.1 65.9 87.1 39.6 55.4 41.1 41.0 51.0 43.7 59.9 5.5 54.9 42.0 45.3 54.3 60.1 37.9 45.6 118.1 44.6 46.6 56.8 41.5 38.8 46.5 31.4 41.0 56.3 54.3 106.7 67.0 57.2 7.9 44.1 182.0 115.0 135.4 99.0 92.4 95.8 146.0 139.3 133.1 220.8 165.1 142.6 143.5 156.8 169.8 121.6 111.5 134.0 173.9 121.9 230.6 151.2 74.5 115.0 91.3 153.5 111.0 164.9 106.8 71.8 118.4 112.1 111.6 120.1 141.2 77.4 174.2 64.7 161.8 163.2 129.5 111.8 108.7 170.1 153.8 108.4 237.2 70.7 144.6 178.5 96.0 71.2 123.8 76.5 122.3 120.8 156.4 117.0 108.9 121.2 171.0 95.8 145.2 45.6 127.0 175.8 79.1 110.5 112.9 77.5 62.4 67.0 51.2 71.9 59.5 63.4 62.7 56.4 73.9 56.4 59.6 59.0 52.7 55.6 73.0 38.5 85.4 75.4 38.8 39.2 41.2 54.0 39.8 42.1 41.1 41.0 42.0 41.5 41.0 44.1 81.2 70.5 58.9 23.5 74.2 86.2 141.9 187.1 50.1 65.5 55.3 51.3 76.6 62.9 140.6 57.0 68.8 162.2 69.4 73.5 135.0 131.0 30.4 92.8 75.3 78.2 70.4 85.2 37.4 106.9 139.9 72.1 38.7 96.3 67.7 68.7 50.0 84.4 92.1 62.2 39.0 58.9 109.9 71.3 67.9 19.9 67.1 61.4 80.0 20.6 90.9 64.6 52.5 38.2 46.7 116.2 46.2 65.5 64.0 85.2 72.5 140.2 116.4 107.6 72.3 66.5 130.6 63.4 82.8 48.9 72.0 237.5 65.0 79.7 73.4 116.6 PSMD1 "P112, Rpn2, S1" ENSG00000173692 "Proteasome 26S subunit, non-ATPase 1" Q99460 2 231056845-231173116 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 247.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021092, HPA036736, HPA036737" Enhanced Approved "Nucleoplasm,Actin filaments" NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Actin filaments" "CAB021092: AB_10123242, HPA036736: AB_2675278, HPA036737: AB_2675279" "unprognostic (9.32e-3)" "unprognostic (2.08e-2)" "unprognostic (1.07e-1)" "unprognostic (3.81e-2)" "unprognostic (2.71e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (8.63e-12)" "prognostic unfavorable (2.34e-4)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "unprognostic (3.09e-3)" "unprognostic (2.49e-1)" "unprognostic (8.91e-3)" "unprognostic (1.10e-2)" "unprognostic (6.26e-2)" "unprognostic (4.16e-2)" "unprognostic (1.70e-3)" 37.3 38.2 21.9 31.7 26.1 20.1 29.0 21.9 33.7 26.3 20.9 34.8 35.5 37.4 25.6 41.5 24.3 20.3 51.3 27.5 28.5 34.1 42.1 27.0 28.8 26.9 24.9 19.2 17.3 72.7 32.9 36.8 28.3 29.7 36.8 25.4 25.8 33.4 136.3 34.9 29.3 44.9 24.5 25.2 27.9 29.0 24.5 36.6 27.4 81.6 38.3 37.3 27.8 24.4 103.9 113.1 120.6 93.8 122.2 88.7 115.4 135.3 139.4 133.4 134.0 136.5 97.6 80.0 123.3 150.5 138.0 95.0 169.4 125.0 174.3 124.3 93.3 148.7 81.6 155.5 62.9 133.3 119.4 76.5 57.8 142.4 73.9 73.4 159.6 70.3 212.1 56.8 158.7 100.3 103.0 68.3 157.8 100.1 89.3 86.0 190.4 77.7 96.5 104.0 78.8 74.1 108.7 94.1 65.7 120.6 75.3 74.7 152.3 101.4 110.8 126.0 129.8 48.6 80.2 140.4 162.7 100.0 123.4 34.6 27.8 18.8 25.1 39.0 27.3 21.0 25.8 23.8 30.9 17.2 19.2 22.9 12.5 35.9 42.5 18.9 32.3 25.7 21.9 26.1 21.9 33.7 27.5 28.5 26.9 24.9 28.3 24.5 24.5 24.4 51.9 51.3 48.5 77.7 32.9 33.1 37.7 57.0 19.9 46.4 23.0 25.8 125.4 31.5 53.0 33.1 41.7 119.2 27.0 63.6 17.6 83.9 6.2 51.2 67.5 51.7 39.4 61.6 100.0 102.2 101.4 54.6 42.3 60.9 103.9 67.8 30.0 86.9 72.3 90.9 96.0 30.0 57.0 44.2 23.5 9.9 34.8 49.8 17.8 54.4 62.6 46.6 29.9 67.3 93.1 98.6 26.2 45.9 49.4 46.5 46.9 32.1 66.9 53.2 72.3 54.6 128.2 247.9 158.8 39.2 33.1 167.5 36.6 65.5 42.9 38.8 PSMD10 p28 ENSG00000101843 "Proteasome 26S subunit, non-ATPase 10" O75832 X 108084207-108091549 "Predicted intracellular proteins" Apoptosis Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002920, CAB010434" Approved Supported "Intermediate filaments,Cytosol" NA NA 250000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" Cytosol "Intermediate filaments" "CAB010434: AB_640866, HPA002920: AB_1079708" "unprognostic (1.59e-3)" "unprognostic (4.12e-3)" "unprognostic (3.83e-1)" "unprognostic (3.00e-1)" "unprognostic (4.65e-2)" "unprognostic (1.50e-2)" "unprognostic (3.85e-3)" "unprognostic (2.35e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-2)" "unprognostic (4.95e-2)" "unprognostic (7.37e-3)" "unprognostic (1.64e-2)" "unprognostic (1.42e-2)" "unprognostic (2.09e-1)" "unprognostic (5.07e-2)" "unprognostic (1.09e-1)" 28.2 38.6 49.4 26.2 52.3 28.7 35.1 54.5 68.3 34.3 47.4 32.7 25.3 36.4 48.3 34.5 44.9 25.8 26.0 49.9 58.9 34.6 33.4 28.6 34.8 55.4 58.6 31.7 18.6 41.4 33.1 40.4 61.4 31.6 33.2 44.6 26.2 30.4 24.8 26.8 27.0 36.2 56.4 27.1 27.8 27.5 57.5 41.9 38.1 23.9 39.1 33.4 27.7 59.4 101.3 100.5 68.9 62.6 102.6 77.3 61.8 81.6 69.2 73.9 64.0 60.7 64.4 86.0 119.7 80.2 107.6 54.0 109.8 80.3 113.4 91.3 94.8 50.5 91.0 78.2 51.8 79.2 54.8 58.2 85.9 67.2 82.2 73.2 186.4 83.2 99.9 114.3 94.0 133.0 75.3 70.9 124.1 96.9 138.3 74.2 97.5 92.7 80.7 64.8 44.2 42.1 124.8 52.4 86.0 87.4 56.5 66.9 130.5 58.1 33.1 98.3 61.4 88.5 128.5 90.5 80.4 109.2 69.7 83.6 46.8 72.3 45.9 58.1 49.0 47.9 45.8 49.2 52.2 48.0 45.6 51.4 22.0 58.3 71.4 53.0 57.8 69.9 49.4 52.3 54.5 68.3 49.9 58.9 55.4 58.6 61.4 56.4 57.5 59.4 14.2 19.2 19.8 3.3 23.4 22.6 25.9 31.8 23.9 15.1 20.4 20.6 11.2 8.6 35.4 11.0 2.1 28.3 12.8 16.5 31.3 19.9 4.1 38.3 26.9 22.8 14.4 35.7 3.4 18.7 35.3 22.6 11.7 21.6 34.1 17.9 22.1 25.6 31.3 13.5 4.5 16.8 16.2 29.5 19.0 4.4 25.7 20.2 17.8 0.0 26.1 18.3 20.6 5.5 9.6 24.5 14.1 21.1 34.7 26.6 14.9 34.8 69.9 7.7 0.0 13.8 32.1 46.2 40.3 32.4 29.1 25.0 20.2 24.6 19.2 33.7 PSMD11 "MGC3844, p44.5, Rpn6, S9" ENSG00000108671 "Proteasome 26S subunit, non-ATPase 11" O00231 17 32444379-32483319 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 308.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042275, HPA067433" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA 95000 "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA042275: AB_10794793, HPA067433: AB_2685838" "unprognostic (1.16e-1)" "unprognostic (2.71e-1)" "unprognostic (6.94e-2)" "unprognostic (2.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.33e-6)" "unprognostic (2.64e-2)" "unprognostic (3.97e-1)" "unprognostic (8.10e-2)" "unprognostic (5.88e-2)" "unprognostic (9.17e-3)" "prognostic unfavorable (5.73e-6)" "unprognostic (9.39e-3)" "unprognostic (6.65e-2)" "unprognostic (2.90e-1)" "unprognostic (2.17e-2)" 26.9 26.5 25.6 29.4 26.4 34.5 22.6 24.6 29.5 22.8 20.3 27.3 27.2 28.8 23.1 36.3 21.8 22.7 37.0 26.0 25.6 30.1 37.7 24.3 30.2 27.0 25.3 20.6 25.9 35.0 18.5 34.1 28.1 25.0 32.0 23.8 23.3 21.8 96.0 33.8 23.2 35.0 24.4 24.0 22.9 34.2 25.9 38.4 21.6 58.6 39.1 34.0 24.8 31.2 127.0 136.8 98.4 106.2 65.4 48.4 103.8 71.5 90.0 151.9 122.0 139.9 111.5 99.1 110.7 77.0 145.9 143.0 114.5 98.5 147.8 50.9 81.2 81.0 68.7 108.3 63.3 95.5 81.6 43.7 51.0 134.3 91.8 49.0 108.7 87.0 155.5 110.9 90.8 78.0 143.1 57.4 134.5 67.4 68.8 89.2 127.2 132.4 75.2 92.2 86.3 58.8 89.8 63.4 71.0 100.3 154.2 45.1 77.8 84.3 99.5 105.6 166.5 62.2 105.0 129.1 122.5 74.8 145.2 48.3 41.2 26.7 40.2 41.8 44.2 36.3 39.1 40.6 46.6 34.2 34.5 36.4 19.1 47.7 45.6 38.2 51.5 45.6 25.6 26.4 24.6 29.5 26.0 25.6 27.0 25.3 28.1 24.4 25.9 31.2 62.7 48.1 31.5 36.6 56.3 126.9 108.7 116.3 44.9 44.5 47.8 40.8 71.9 41.5 78.0 25.8 31.3 178.2 57.8 87.5 80.3 117.8 205.4 45.8 46.2 69.7 48.8 100.8 36.0 107.3 146.1 63.8 43.8 59.9 45.7 79.8 55.3 107.0 92.3 37.0 36.4 58.7 77.3 48.4 72.6 48.0 49.0 61.1 26.6 15.9 77.5 63.1 40.2 33.2 55.6 117.2 48.0 48.5 79.3 131.9 66.4 120.6 52.6 43.3 52.6 68.0 189.7 152.7 98.4 85.3 117.5 308.9 54.8 52.0 67.6 109.5 PSMD12 "p55, Rpn5" ENSG00000197170 "Proteasome 26S subunit, non-ATPase 12" O00232 17 67337916-67366605 "Disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023119 Approved Approved Nucleoplasm,Microtubules,Cytosol NA NA 73000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Microtubules "Nucleoplasm, Cytosol" "HPA023119: AB_1855845" "unprognostic (6.06e-2)" "unprognostic (3.16e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.35e-2)" "unprognostic (2.28e-1)" "unprognostic (1.97e-3)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.28e-2)" "unprognostic (3.72e-2)" "prognostic favorable (6.32e-4)" "unprognostic (2.63e-1)" "unprognostic (7.32e-3)" "prognostic unfavorable (4.73e-6)" "unprognostic (1.52e-2)" "unprognostic (1.82e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" 14.8 13.9 11.2 11.4 12.2 12.5 11.9 15.0 19.4 9.4 9.7 10.4 8.2 10.5 10.9 12.5 7.6 9.7 13.7 12.6 17.2 14.9 28.0 9.4 10.8 17.8 17.8 9.1 15.6 14.8 7.6 11.0 18.9 10.7 11.6 8.9 10.0 7.7 35.8 10.3 8.7 11.3 12.9 9.4 11.2 14.4 16.0 12.1 10.3 29.1 15.1 14.7 8.0 12.5 63.8 38.5 29.2 32.2 21.9 26.3 40.6 44.2 27.9 47.8 42.0 40.4 27.4 36.6 28.0 35.9 37.4 37.0 51.1 45.1 70.7 17.8 38.5 43.2 29.9 41.1 28.6 44.7 25.0 29.6 29.4 45.3 35.2 21.2 47.6 27.8 57.4 21.0 45.0 43.5 41.0 42.6 35.7 30.0 50.1 20.9 75.6 32.5 36.1 52.0 28.0 40.6 32.9 62.6 45.2 34.1 45.0 36.9 49.5 50.5 34.4 38.6 81.4 21.4 35.2 30.5 59.8 46.5 29.9 14.0 9.9 8.9 8.7 16.7 12.3 8.0 11.5 9.9 10.3 8.9 10.1 10.7 7.3 10.9 19.6 7.0 12.1 8.7 11.2 12.2 15.0 19.4 12.6 17.2 17.8 17.8 18.9 12.9 16.0 12.5 59.6 48.1 58.8 9.8 37.9 112.3 119.5 109.0 43.3 40.8 37.9 33.0 108.1 25.8 97.7 46.0 25.0 88.3 47.9 29.7 70.5 80.7 158.1 99.1 62.3 73.8 32.9 67.3 21.0 78.7 88.8 64.0 33.1 125.3 50.6 39.9 41.0 84.1 56.0 92.5 22.0 28.6 65.1 44.7 90.6 197.0 46.3 50.6 48.0 10.3 59.8 58.6 37.0 14.6 15.0 84.9 22.7 44.0 58.2 93.4 26.0 77.2 68.1 44.6 26.3 78.6 146.8 126.2 108.0 52.9 94.8 123.0 53.8 53.8 34.1 123.2 PSMD14 "pad1, POH1, Rpn11" ENSG00000115233 "Proteasome 26S subunit, non-ATPase 14" O00487 2 161308425-161411717 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002114, HPA003828" Approved Supported Nucleoplasm NA NA 26000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA002114: AB_1855850, HPA003828: AB_2667057" "unprognostic (3.50e-3)" "unprognostic (1.48e-1)" "unprognostic (9.61e-2)" "unprognostic (6.63e-2)" "unprognostic (2.57e-1)" "unprognostic (7.61e-3)" "prognostic unfavorable (2.66e-8)" "unprognostic (3.11e-2)" "unprognostic (4.04e-2)" "unprognostic (3.90e-3)" "unprognostic (9.84e-3)" "unprognostic (3.02e-1)" "prognostic unfavorable (3.10e-6)" "unprognostic (2.86e-2)" "unprognostic (4.70e-2)" "unprognostic (3.54e-1)" "unprognostic (1.66e-1)" 35.2 38.3 38.6 39.7 40.0 38.8 36.4 42.5 47.5 26.2 36.7 35.2 29.1 24.7 30.1 40.7 27.3 23.7 44.6 40.7 43.3 44.4 48.4 26.9 37.8 42.1 41.7 14.5 25.6 51.1 21.4 42.0 43.7 31.0 41.0 37.9 20.8 29.9 98.0 33.2 26.4 39.6 43.8 22.9 27.2 38.7 41.1 49.7 34.7 76.0 52.0 42.5 19.6 46.6 170.3 145.8 158.8 140.8 113.9 97.0 194.2 173.6 168.2 246.1 198.6 216.2 140.2 200.2 258.0 128.7 144.3 126.5 176.8 185.6 244.6 210.3 133.1 200.8 110.8 245.9 139.7 196.7 113.8 74.4 138.8 277.4 256.8 94.0 185.5 117.1 222.1 139.6 207.7 164.1 145.0 148.0 220.5 124.3 218.2 123.6 154.4 196.0 218.6 145.0 138.4 101.3 117.8 131.7 167.5 131.4 90.2 124.3 147.2 162.7 152.4 111.6 193.8 82.5 242.7 186.7 174.1 129.6 182.2 47.4 48.2 25.2 65.3 69.6 68.7 64.2 69.4 71.0 75.4 57.4 55.4 66.5 4.9 70.2 56.2 74.5 83.7 73.3 38.6 40.0 42.5 47.5 40.7 43.3 42.1 41.7 43.7 43.8 41.1 46.6 40.1 51.3 38.2 35.3 49.4 49.5 48.1 146.8 25.0 43.7 40.2 36.2 89.8 52.9 80.3 23.9 18.8 159.5 60.4 47.7 90.1 124.3 82.5 52.4 51.8 49.9 52.5 56.2 64.0 118.3 154.6 48.1 29.6 58.4 51.2 59.0 31.8 125.3 104.7 47.1 56.1 53.5 118.0 41.1 40.0 36.0 27.7 46.1 48.0 25.3 61.1 87.7 44.3 50.3 64.6 155.0 48.0 34.3 60.2 57.0 36.5 106.1 55.4 60.6 32.9 36.6 64.5 137.0 77.7 34.3 56.0 220.3 47.8 63.6 64.5 50.8 PSMD2 "MGC14274, P97, Rpn1, S2, TRAP2" ENSG00000175166 "Proteasome 26S subunit, non-ATPase 2" Q13200 3 184299198-184309050 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 332.9" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 349.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045192, HPA062363" Enhanced NA NA 430000 "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA045192: AB_10961324, HPA062363: " "unprognostic (1.06e-2)" "unprognostic (1.69e-2)" "unprognostic (6.82e-2)" "unprognostic (2.43e-2)" "unprognostic (2.96e-1)" "prognostic unfavorable (9.98e-4)" "prognostic unfavorable (6.63e-7)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.69e-1)" "unprognostic (4.68e-2)" "unprognostic (1.51e-2)" "unprognostic (1.32e-1)" "unprognostic (4.25e-3)" "unprognostic (1.53e-1)" "unprognostic (9.12e-2)" "unprognostic (1.13e-2)" "unprognostic (2.74e-3)" 64.1 102.6 65.0 61.9 67.6 77.8 53.3 68.3 71.7 58.4 65.1 73.2 49.4 69.1 45.5 84.3 53.5 41.3 116.3 67.6 73.7 62.7 68.8 59.3 57.9 74.8 81.1 50.3 48.0 82.9 58.8 58.4 84.6 52.2 63.2 46.9 60.6 59.8 332.9 79.7 55.8 76.7 68.9 59.1 63.4 101.9 73.2 73.4 55.3 183.3 77.1 64.5 58.8 65.2 800.0 248.6 194.3 328.7 226.2 129.6 238.8 478.3 363.6 580.3 327.6 349.1 163.4 251.5 643.4 393.8 467.1 254.3 290.3 516.4 725.0 383.6 234.1 268.4 229.6 211.9 123.7 191.9 211.8 147.3 156.8 549.5 339.0 219.1 353.6 188.9 201.1 226.9 476.0 310.7 199.4 110.1 279.4 290.8 438.1 217.6 287.8 262.9 240.4 248.7 174.5 134.7 376.2 321.3 174.7 208.4 446.5 145.1 463.6 361.2 383.9 293.3 1049.9 219.7 501.3 412.9 438.7 204.2 256.7 48.8 86.0 82.2 61.9 74.5 56.7 59.0 60.1 68.0 103.1 53.5 58.5 56.3 26.6 76.7 79.6 48.3 66.9 96.3 65.0 67.6 68.3 71.7 67.6 73.7 74.8 81.1 84.6 68.9 73.2 65.2 49.0 67.3 61.7 13.4 53.4 71.1 66.2 101.1 58.1 66.9 38.7 31.5 113.3 38.6 81.8 57.0 20.9 153.8 60.6 67.3 90.1 183.2 161.8 56.1 55.0 63.0 79.6 105.9 21.0 130.8 117.9 60.3 45.3 61.3 40.5 111.3 35.0 60.5 83.8 72.3 20.0 40.0 79.3 38.8 54.0 90.3 48.7 58.5 53.4 15.9 94.1 117.1 51.5 12.5 16.6 349.2 33.3 65.8 84.4 63.1 59.1 97.0 71.5 60.5 32.9 48.2 183.0 184.6 138.9 65.2 67.1 222.9 53.0 94.3 55.8 57.7 PSMD4 "AF, AF-1, Rpn10, S5A" ENSG00000159352 "Proteasome 26S subunit, non-ATPase 4" P55036 1 151254709-151267479 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038807, HPA039252, CAB047300" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 69000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB047300: , HPA038807: AB_2676217, HPA039252: AB_10673418" "unprognostic (3.83e-2)" "unprognostic (7.89e-2)" "unprognostic (6.86e-3)" "unprognostic (1.70e-1)" "unprognostic (2.63e-1)" "unprognostic (2.89e-2)" "unprognostic (1.79e-3)" "unprognostic (2.16e-1)" "unprognostic (2.81e-1)" "unprognostic (2.61e-2)" "unprognostic (7.57e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (6.66e-10)" "unprognostic (9.80e-2)" "unprognostic (6.60e-2)" "unprognostic (2.03e-2)" "unprognostic (3.91e-1)" 108.8 118.0 198.8 77.8 203.8 89.4 97.9 203.0 288.1 88.7 195.2 136.9 68.9 99.5 114.3 115.5 91.0 58.2 191.2 202.8 205.8 110.2 170.5 81.7 95.7 208.5 215.3 85.8 114.0 91.6 79.4 91.1 209.3 91.3 82.1 64.5 83.9 86.4 404.1 103.3 91.3 91.0 204.2 109.6 115.4 152.0 203.7 114.3 76.7 188.0 114.0 118.6 88.2 203.4 251.4 294.8 213.4 175.2 227.4 167.0 231.9 166.0 202.1 258.6 205.1 388.3 278.2 202.2 396.2 235.4 178.7 255.4 277.1 250.6 219.6 331.9 236.6 197.8 256.2 396.6 250.8 234.7 220.5 182.5 204.2 296.3 271.4 193.3 229.5 222.4 313.6 247.9 220.2 723.5 217.4 276.7 406.0 384.3 293.4 181.6 207.7 364.7 252.7 210.6 166.7 283.8 184.5 266.3 222.7 313.0 278.9 452.3 203.4 128.1 201.2 159.2 288.2 295.1 397.7 430.3 212.6 218.1 238.7 439.4 439.0 713.9 247.3 478.1 281.2 399.0 287.4 274.4 398.4 426.1 261.0 258.1 580.2 351.2 502.3 240.3 476.6 651.0 198.8 203.8 203.0 288.1 202.8 205.8 208.5 215.3 209.3 204.2 203.7 203.4 90.1 57.7 62.9 15.7 78.5 88.6 111.9 249.0 58.1 50.9 60.9 69.3 245.2 82.9 125.0 60.7 27.1 328.6 74.0 104.1 168.3 177.3 279.1 91.5 63.0 95.8 84.2 107.3 25.3 186.9 234.1 88.5 46.9 59.1 83.6 88.8 83.2 116.0 184.5 33.7 24.2 94.1 156.6 104.0 98.0 243.2 105.3 90.3 104.9 11.2 256.6 91.9 115.4 16.1 23.2 172.2 129.1 98.6 67.0 121.4 168.6 206.6 148.3 54.6 118.3 79.0 221.1 234.8 83.5 66.7 86.5 414.6 77.7 105.6 114.5 107.2 PSMD6 "KIAA0107, p44S10, Rpn7, S10" ENSG00000163636 "Proteasome 26S subunit, non-ATPase 6" Q15008 3 64010550-64024010 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 285.7" "Cell type enhanced" "Detected in all" "Early spermatids: 513.3;Late spermatids: 717.7;Spermatocytes: 336.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 7 "MCF7: 1458.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036921, HPA036922" Uncertain NA NA 120000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "HPA036921: AB_2675383, HPA036922: AB_10670850" "unprognostic (3.44e-2)" "unprognostic (2.03e-1)" "unprognostic (4.76e-3)" "unprognostic (1.95e-1)" "unprognostic (2.43e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (8.65e-2)" "unprognostic (1.38e-1)" "unprognostic (1.95e-3)" "unprognostic (6.69e-2)" "unprognostic (4.73e-2)" "unprognostic (4.06e-3)" "unprognostic (4.20e-2)" "unprognostic (1.89e-1)" "unprognostic (9.55e-2)" "unprognostic (8.22e-3)" 47.2 67.9 43.9 43.3 45.2 115.0 49.5 47.5 63.2 37.1 44.7 46.2 34.0 43.1 60.1 61.4 35.2 28.2 74.9 46.2 47.5 62.9 74.9 37.9 50.2 47.5 47.5 32.8 285.7 72.9 30.8 54.2 49.2 42.1 43.4 48.4 43.7 45.6 160.8 54.6 34.8 49.5 49.2 38.8 46.1 120.2 45.2 54.8 40.3 90.9 63.9 52.3 40.4 49.0 98.4 102.5 141.1 99.5 97.6 87.0 125.9 136.3 128.8 221.5 162.4 193.0 79.8 136.9 57.6 132.4 154.7 66.1 166.4 144.7 207.3 141.1 104.6 183.6 76.3 128.2 142.9 204.9 112.2 93.7 100.8 184.2 80.3 107.4 141.5 117.7 187.3 86.1 157.8 1458.7 141.0 125.3 180.7 157.3 71.9 117.2 101.1 132.4 177.1 140.7 52.1 85.0 101.6 85.4 136.2 123.4 74.3 125.0 125.7 98.1 106.5 145.2 217.1 108.2 171.0 204.1 144.3 190.8 116.1 99.2 113.9 140.3 103.4 133.0 107.3 124.7 114.0 112.9 120.1 120.3 113.6 110.5 139.4 111.5 139.8 84.0 137.1 167.2 43.9 45.2 47.5 63.2 46.2 47.5 47.5 47.5 49.2 49.2 45.2 49.0 46.4 32.1 43.2 7.5 48.7 62.1 71.7 152.5 27.9 37.0 33.9 34.9 100.0 22.8 86.4 44.1 22.9 197.8 47.3 27.6 86.1 104.0 513.3 49.0 42.3 55.3 25.8 99.9 11.7 133.7 102.3 47.6 27.0 48.9 45.6 46.7 28.9 47.4 92.2 33.7 10.9 27.3 73.2 38.1 40.5 717.7 51.9 51.7 48.0 4.7 71.0 81.8 39.1 10.1 15.4 87.1 30.4 51.1 58.1 44.7 29.7 95.9 73.0 41.2 59.2 41.3 145.8 336.9 131.3 53.4 69.9 290.6 50.4 68.7 35.8 66.1 PSMD7 "MOV34, P40, Rpn8, S12" ENSG00000103035 "Proteasome 26S subunit, non-ATPase 7" P51665 16 74296814-74306288 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 596.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019379, HPA049824, HPA056069" Enhanced Enhanced Nucleoplasm NA NA 190000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB019379: , HPA049824: AB_2680899, HPA056069: AB_2683025" "unprognostic (4.75e-3)" "unprognostic (1.30e-1)" "unprognostic (2.84e-2)" "unprognostic (6.95e-2)" "unprognostic (7.62e-2)" "prognostic unfavorable (6.64e-5)" "prognostic unfavorable (7.71e-6)" "unprognostic (1.97e-2)" "unprognostic (6.51e-2)" "unprognostic (1.91e-2)" "unprognostic (9.34e-3)" "unprognostic (1.34e-2)" "unprognostic (2.52e-2)" "unprognostic (5.06e-3)" "unprognostic (7.04e-2)" "unprognostic (2.12e-1)" "unprognostic (1.86e-2)" 68.9 78.8 51.6 52.1 52.9 126.7 57.5 54.5 69.3 50.1 50.9 75.8 47.3 59.5 59.3 85.8 44.0 41.2 124.8 53.0 54.2 57.3 75.1 52.6 62.3 54.3 54.1 37.8 49.0 49.0 41.7 70.2 55.6 68.3 65.4 47.3 59.7 59.2 265.8 85.5 55.6 62.4 54.3 56.5 58.0 42.0 55.0 71.9 42.0 159.5 71.2 73.1 62.2 56.7 140.1 226.2 170.6 89.0 120.1 122.1 209.8 191.6 166.2 236.2 212.7 301.9 189.8 190.1 207.7 156.7 103.2 176.3 135.0 175.1 215.4 113.3 146.3 147.2 169.1 235.9 156.0 241.3 241.3 112.4 176.3 213.4 213.0 106.0 207.0 119.2 222.2 82.1 153.5 345.4 147.0 232.1 184.9 145.0 113.8 198.8 106.9 251.6 125.1 207.3 106.9 119.3 185.7 70.4 114.9 130.5 148.7 166.6 187.5 137.5 116.0 152.5 146.5 174.6 241.4 560.2 186.6 174.1 145.2 152.4 163.6 193.4 133.2 176.2 130.5 149.7 131.8 141.2 201.9 110.5 126.6 131.2 98.7 139.5 187.4 172.2 168.2 187.8 51.6 52.9 54.5 69.3 53.0 54.2 54.3 54.1 55.6 54.3 55.0 56.7 74.4 67.3 59.4 16.6 84.2 104.4 183.5 167.8 64.3 59.6 47.0 47.5 53.3 57.2 114.9 46.0 8.4 337.1 69.5 120.4 80.3 158.5 153.8 76.3 80.6 96.2 85.5 121.0 22.7 190.9 229.8 87.7 67.8 80.3 103.9 76.7 66.0 147.6 188.5 57.2 21.3 100.1 122.1 75.1 91.2 25.3 56.5 95.1 99.6 9.4 119.5 86.0 81.4 15.6 25.7 164.0 104.1 65.5 121.4 259.6 93.9 109.4 88.1 59.9 92.1 68.4 186.1 184.2 88.7 103.6 129.3 596.1 86.2 114.0 110.3 197.8 PSME2 PA28beta ENSG00000100911 "Proteasome activator subunit 2" Q9UL46 14 24143362-24147570 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 1063.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062661 Approved Nucleoplasm NA NA 5900000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA062661: AB_2684825" "prognostic favorable (1.27e-4)" "unprognostic (7.55e-3)" "unprognostic (2.84e-1)" "unprognostic (8.72e-2)" "unprognostic (2.69e-1)" "unprognostic (1.50e-1)" "unprognostic (3.71e-1)" "unprognostic (1.02e-1)" "unprognostic (2.30e-2)" "unprognostic (2.90e-3)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.47e-5)" "unprognostic (3.09e-2)" "unprognostic (3.00e-1)" "unprognostic (6.43e-3)" "unprognostic (3.07e-3)" 81.3 204.5 25.7 86.6 26.0 42.8 79.7 25.5 40.1 93.7 28.8 104.6 165.9 68.6 48.6 112.5 75.0 30.6 105.3 25.7 28.2 142.0 228.1 107.9 89.6 30.7 26.5 71.7 102.1 27.7 123.7 30.7 27.5 94.1 79.2 18.1 84.0 33.8 63.7 72.6 152.9 44.0 28.1 204.6 101.6 56.9 28.7 52.1 92.2 26.6 80.2 74.0 80.6 27.8 95.2 93.2 59.5 140.6 42.8 59.9 85.6 47.7 108.4 145.7 182.4 72.7 183.9 111.0 30.7 59.8 166.5 79.1 32.1 92.0 87.6 198.6 28.9 75.2 45.8 277.1 135.9 103.4 100.1 61.2 26.3 115.1 44.1 65.6 79.3 78.2 37.2 165.2 61.5 188.6 204.2 140.0 19.8 142.3 112.1 189.2 93.2 119.2 108.9 209.4 36.8 47.7 101.6 168.8 70.3 31.0 89.0 110.7 63.4 80.7 75.1 38.2 102.5 143.7 215.1 140.7 52.9 110.0 99.7 110.3 605.5 217.5 421.1 1217.1 431.5 432.6 412.2 415.9 504.7 357.2 305.7 373.8 192.3 543.4 801.7 375.6 447.3 1562.7 25.7 26.0 25.5 40.1 25.7 28.2 30.7 26.5 27.5 28.1 28.7 27.8 185.3 51.3 113.7 5.2 198.5 154.9 174.3 754.8 126.3 39.7 104.5 120.8 69.5 140.2 287.7 117.7 22.9 296.6 223.6 316.1 299.3 370.5 12.6 113.0 147.3 159.7 98.0 74.2 1.7 567.1 296.6 128.6 132.5 109.9 141.5 83.4 69.7 236.6 332.1 28.6 2.2 288.5 319.4 143.7 224.9 15.5 74.0 237.8 136.9 2.8 763.7 69.8 326.5 2.5 1.3 303.1 324.5 77.8 389.3 282.8 1063.1 373.6 293.7 19.2 46.0 62.0 453.3 54.6 24.8 144.5 139.8 228.2 228.6 229.0 338.5 224.4 PSMG4 "C6orf86, PAC4" ENSG00000180822 "Proteasome assembly chaperone 4" Q5JS54 6 3231403-3303373 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067652, HPA074376, HPA075846" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Mitochondria" "HPA067652: AB_2685880, HPA074376: , HPA075846: " "unprognostic (3.13e-3)" "unprognostic (6.00e-2)" "unprognostic (3.60e-1)" "unprognostic (4.11e-2)" "unprognostic (4.11e-1)" "unprognostic (2.20e-1)" "unprognostic (6.52e-3)" "unprognostic (1.57e-2)" "unprognostic (6.96e-2)" "unprognostic (6.74e-3)" "unprognostic (7.40e-3)" "unprognostic (3.02e-2)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.59e-1)" "unprognostic (8.18e-2)" "unprognostic (2.54e-1)" "unprognostic (3.48e-2)" 20.3 18.3 12.8 8.2 15.7 13.8 20.0 19.8 13.7 16.9 5.0 24.1 14.1 18.9 18.6 19.9 18.4 6.9 15.1 11.5 14.6 20.1 26.9 13.7 10.2 17.6 16.0 16.6 33.4 12.0 22.2 7.0 18.1 19.3 6.9 9.9 20.2 13.4 37.1 20.8 16.8 9.5 13.5 14.4 21.4 16.2 15.9 9.3 21.1 11.1 7.7 19.8 16.8 23.8 61.8 29.0 17.5 42.8 15.3 23.1 29.5 27.2 20.0 25.9 41.4 25.1 20.6 21.0 73.1 16.4 20.2 28.9 15.0 18.9 16.9 34.7 65.2 16.9 33.4 66.6 19.2 48.7 16.9 19.8 20.1 18.8 27.8 14.8 32.4 39.9 65.0 15.1 14.0 58.2 27.6 88.9 21.4 31.3 57.7 36.5 9.5 116.2 21.1 24.0 74.3 21.3 12.9 16.7 61.4 16.5 22.0 21.0 31.7 21.4 20.4 24.6 26.6 48.7 76.4 39.4 15.2 34.1 29.3 16.2 35.5 24.4 25.3 36.9 29.4 50.2 42.1 30.8 28.4 52.1 40.9 35.7 8.9 32.3 36.3 33.9 39.4 23.9 12.8 15.7 19.8 13.7 11.5 14.6 17.6 16.0 18.1 13.5 15.9 23.8 45.2 22.4 21.2 18.6 25.3 27.9 29.1 44.2 38.7 32.0 53.1 88.4 21.9 37.1 26.9 44.1 8.4 39.3 15.2 23.6 84.1 43.9 31.4 23.6 25.9 35.2 22.8 18.5 9.6 87.5 37.8 30.4 15.8 17.1 22.2 38.8 28.2 64.5 35.1 25.2 17.8 31.1 28.5 19.2 21.1 13.3 37.0 18.4 30.2 5.6 35.7 22.0 32.0 21.6 15.7 57.8 25.8 23.0 18.9 47.0 47.3 67.2 22.6 29.4 46.0 45.5 54.0 29.6 78.2 39.6 38.2 12.0 23.7 30.0 35.4 27.1 PTRH2 "BIT1, CFAP37, CGI-147, PTH2" ENSG00000141378 "Peptidyl-tRNA hydrolase 2" Q9Y3E5 17 59674636-59707626 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Apoptosis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012897 Supported Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA012897: AB_1855949" "unprognostic (2.26e-1)" "unprognostic (2.80e-2)" "unprognostic (1.02e-2)" "unprognostic (3.89e-2)" "unprognostic (1.31e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.38e-2)" "unprognostic (2.02e-1)" "unprognostic (9.59e-3)" "unprognostic (2.72e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.01e-8)" "unprognostic (5.43e-3)" "unprognostic (6.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.49e-2)" 20.8 25.9 24.3 17.3 25.1 14.5 27.6 25.0 31.9 19.7 23.6 24.1 15.3 18.8 48.5 18.1 18.4 18.2 14.5 25.1 26.1 18.5 45.7 14.7 19.0 25.9 26.1 16.9 19.5 18.6 14.1 18.6 26.7 20.7 27.5 10.2 15.9 18.6 25.0 15.7 13.2 22.9 24.8 17.5 16.1 19.5 24.9 17.3 16.2 20.9 24.1 44.0 11.8 27.4 75.9 142.9 44.3 40.8 84.8 72.6 47.4 70.6 63.8 60.7 89.0 94.1 57.7 54.1 105.0 60.9 101.1 73.3 98.4 93.8 89.4 104.2 133.2 96.7 72.3 176.2 129.4 86.0 52.5 82.0 120.9 93.9 108.5 42.8 102.5 37.4 111.3 58.2 92.4 187.9 74.2 71.2 38.0 194.5 113.4 39.1 74.8 80.7 103.7 109.2 57.9 74.2 36.7 39.6 91.5 50.7 93.1 61.1 67.2 77.8 77.8 47.1 77.9 73.6 91.9 82.3 50.7 54.4 60.4 6.1 69.0 2.9 22.7 67.4 30.9 43.1 26.3 25.7 50.0 33.1 37.4 27.0 29.0 34.8 86.0 59.4 34.0 37.9 24.3 25.1 25.0 31.9 25.1 26.1 25.9 26.1 26.7 24.8 24.9 27.4 21.4 16.0 13.6 5.5 18.7 36.7 50.1 48.1 27.9 4.1 17.1 22.4 15.4 11.5 51.6 11.0 4.2 26.8 13.0 8.9 11.7 27.2 22.1 23.4 33.1 22.5 6.7 17.9 9.8 25.6 25.0 29.7 17.3 24.1 22.8 12.8 12.8 31.5 16.9 8.4 9.1 10.3 22.4 9.7 17.2 12.0 17.4 14.6 14.2 2.8 11.4 7.2 13.4 7.5 11.5 28.8 12.3 9.8 24.8 35.1 10.0 16.5 33.3 3.4 13.1 25.4 32.2 33.4 13.3 21.3 35.7 31.7 12.6 22.4 16.7 37.5 PTTG2 ENSG00000250254 "Pituitary tumor-transforming 2" Q9NZH5 4 37960398-37961128 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.7;Early spermatids: 5.2;Langerhans cells: 12.9;Smooth muscle cells: 3.7;Spermatocytes: 4.3;Suprabasal keratinocytes: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008890, HPA045034" Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoli "HPA008890: AB_1079717, HPA045034: AB_2679192" "unprognostic (3.29e-1)" "unprognostic (4.41e-4)" "unprognostic (1.11e-1)" "unprognostic (2.07e-2)" "unprognostic (1.74e-2)" "unprognostic (9.58e-2)" "unprognostic (2.27e-1)" "unprognostic (2.74e-1)" "unprognostic (7.07e-2)" "unprognostic (2.74e-2)" "unprognostic (2.20e-1)" "unprognostic (3.46e-2)" "unprognostic (1.64e-1)" "unprognostic (1.34e-1)" "unprognostic (3.32e-1)" "unprognostic (8.60e-5)" 0.2 0.0 0.5 0.2 0.7 1.1 0.1 0.6 1.0 0.4 0.2 1.4 0.0 0.5 0.3 0.1 0.5 0.2 1.0 1.0 0.0 0.3 0.3 0.4 0.2 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.4 0.3 0.1 0.0 0.1 0.2 0.7 0.1 0.4 0.3 0.1 0.9 0.3 0.0 0.1 0.1 0.2 0.6 0.2 0.6 0.3 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.7 0.6 1.0 1.0 0.0 0.3 0.1 0.4 0.1 0.1 1.0 0.3 0.0 0.0 0.0 0.8 4.7 0.7 0.7 0.0 0.0 0.1 0.0 1.1 0.0 0.2 0.0 0.0 0.6 1.5 0.0 0.0 0.0 5.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.6 12.9 0.5 0.6 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.6 3.7 4.3 0.2 0.0 2.8 0.0 0.6 0.0 0.2 0.4 PUF60 "FIR, RoBPI, SIAHBP1" ENSG00000179950 "Poly(U) binding splicing factor 60" Q9UHX1 8 143816344-143829352 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Repressor, Ribonucleoprotein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 332.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045733, HPA052096, HPA059714" Enhanced Enhanced Nucleoplasm NA NA 70000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA045733: AB_10960503, HPA052096: AB_2681722, HPA059714: AB_2684110" "unprognostic (3.49e-2)" "unprognostic (8.78e-2)" "unprognostic (2.66e-1)" "unprognostic (4.05e-2)" "unprognostic (1.81e-2)" "unprognostic (3.47e-2)" "unprognostic (1.51e-2)" "unprognostic (4.34e-3)" "unprognostic (2.64e-2)" "unprognostic (1.07e-2)" "unprognostic (1.75e-1)" "unprognostic (5.45e-2)" "unprognostic (2.36e-2)" "unprognostic (2.64e-2)" "unprognostic (7.00e-2)" "unprognostic (2.28e-2)" "unprognostic (3.42e-2)" 71.6 73.5 7.9 11.0 7.6 39.6 75.5 8.1 22.9 71.4 5.3 84.8 22.3 84.9 5.9 84.9 76.3 7.3 88.5 7.8 15.4 82.8 124.3 64.0 17.7 12.2 11.6 57.2 62.9 11.7 71.0 19.2 14.1 67.2 5.8 1.3 63.3 17.8 125.5 108.7 69.5 10.5 7.3 72.3 73.2 70.8 14.5 15.9 59.8 9.0 9.7 74.5 68.6 12.4 95.7 211.5 36.7 31.3 16.6 15.6 62.7 74.4 27.4 70.3 75.1 95.4 103.9 89.4 71.2 58.9 52.8 83.0 86.5 91.4 3.6 91.4 147.7 110.2 117.0 106.3 60.4 38.5 70.0 45.4 61.8 89.8 26.9 21.1 69.0 92.1 88.7 37.4 20.5 332.5 156.1 26.4 77.8 63.3 191.6 84.2 42.9 91.8 19.5 91.8 71.5 80.3 101.6 40.4 77.7 9.1 116.7 21.4 79.0 72.9 176.2 85.7 98.6 66.7 103.9 109.7 70.7 73.3 71.9 90.8 112.6 99.8 129.0 133.7 139.3 116.8 103.1 128.6 127.1 135.9 98.6 113.1 58.8 132.6 137.6 76.8 139.0 193.9 7.9 7.6 8.1 22.9 7.8 15.4 12.2 11.6 14.1 7.3 14.5 12.4 70.2 38.5 46.4 21.5 64.7 107.7 102.1 197.4 65.4 62.8 51.3 67.9 63.7 51.5 103.0 29.5 29.2 146.6 56.4 98.0 92.0 110.7 20.5 65.6 55.3 67.3 66.9 65.0 8.2 89.8 134.3 68.4 74.9 60.3 55.8 75.0 41.7 76.8 101.1 43.7 8.3 75.9 118.0 44.0 62.3 47.8 64.0 52.3 90.7 6.5 105.2 182.6 81.4 9.5 23.7 98.2 91.4 59.0 52.7 83.0 91.9 118.1 85.4 64.8 65.7 57.1 122.9 104.2 128.5 63.1 107.1 173.3 74.2 99.3 97.7 81.2 PURA "PUR-ALPHA, PUR1, PURALPHA" ENSG00000185129 "Purine rich element binding protein A" Q00577 5 140107777-140125619 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Horizontal cells: 220.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 260000 "Cluster 15: NK-cells - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "unprognostic (2.69e-1)" "unprognostic (1.23e-1)" "unprognostic (2.36e-1)" "unprognostic (3.72e-1)" "unprognostic (1.10e-1)" "unprognostic (4.01e-1)" "unprognostic (1.43e-1)" "unprognostic (1.09e-1)" "unprognostic (2.41e-1)" "unprognostic (2.33e-1)" "unprognostic (3.04e-1)" "unprognostic (9.28e-2)" "prognostic favorable (4.77e-5)" "unprognostic (2.75e-1)" "unprognostic (4.24e-1)" "unprognostic (8.98e-2)" "unprognostic (2.09e-1)" 7.6 9.0 29.6 8.1 19.3 2.5 5.2 11.3 18.6 8.5 0.0 6.4 10.0 6.9 5.5 5.7 5.6 5.6 8.4 14.4 22.7 12.2 8.6 6.8 6.0 24.2 21.4 10.1 7.2 13.5 4.8 8.1 23.6 9.5 4.4 12.6 9.7 8.0 9.6 7.3 9.0 5.6 24.0 9.8 9.4 5.2 26.7 5.8 11.7 8.2 5.7 5.9 4.8 25.8 15.1 9.2 3.7 21.5 9.3 13.4 20.1 32.5 13.4 15.0 11.7 19.2 15.5 15.8 25.2 12.7 10.0 13.4 8.9 18.6 12.7 25.7 28.0 11.8 13.1 6.7 5.8 9.6 19.0 6.2 8.9 14.1 8.5 9.7 4.3 11.3 11.1 16.4 7.7 18.6 15.3 12.1 4.7 5.0 23.3 15.4 14.6 11.3 9.4 11.9 11.7 12.1 16.5 19.1 18.7 3.6 17.2 9.2 15.2 26.8 19.5 9.5 23.4 26.0 13.5 16.8 12.7 10.5 22.7 6.4 1.8 3.4 2.8 1.2 2.1 3.0 3.1 3.2 1.6 3.7 2.7 3.4 0.9 5.2 1.5 2.5 2.9 1.0 29.6 19.3 11.3 18.6 14.4 22.7 24.2 21.4 23.6 24.0 26.7 25.8 82.2 51.3 43.3 28.4 43.5 34.3 48.5 15.0 54.1 162.0 58.5 62.2 76.2 62.9 21.7 77.3 125.1 47.2 53.6 48.8 13.7 22.2 25.4 46.2 66.4 71.2 62.9 27.8 45.3 25.4 44.4 57.5 49.5 40.8 25.4 35.9 77.4 62.1 26.4 220.4 46.0 47.9 12.2 32.3 26.2 10.0 76.4 29.2 37.4 34.7 27.0 95.1 49.4 27.2 43.4 26.4 33.9 102.0 43.5 61.7 57.6 48.9 22.5 106.7 72.3 99.8 76.7 38.6 38.7 39.7 45.5 43.4 49.9 52.7 44.0 48.8 PURB PURBETA ENSG00000146676 "Purine rich element binding protein B" Q96QR8 7 44876299-44885530 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048766 Supported Nucleoplasm NA NA 150000 "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA048766: " "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (3.21e-2)" "unprognostic (9.49e-2)" "unprognostic (4.96e-2)" "unprognostic (2.18e-1)" "unprognostic (8.44e-3)" "unprognostic (1.53e-1)" "unprognostic (1.72e-1)" "unprognostic (1.88e-3)" "unprognostic (2.01e-1)" "unprognostic (4.12e-1)" "unprognostic (5.66e-2)" "unprognostic (4.29e-2)" "unprognostic (7.96e-2)" "unprognostic (1.41e-1)" "unprognostic (3.22e-2)" 10.6 7.8 8.2 10.7 9.5 13.5 11.7 17.4 10.7 10.4 7.4 12.7 7.5 10.7 7.5 11.3 9.3 7.8 8.1 9.7 7.0 9.2 8.6 10.4 10.2 6.9 8.1 9.9 8.4 10.9 7.5 13.1 6.9 10.3 7.4 25.0 9.0 9.1 12.2 14.1 8.9 9.7 7.3 9.8 8.9 5.9 7.9 13.4 11.5 9.2 10.4 9.7 9.3 11.1 16.4 9.0 15.9 30.0 14.5 22.9 10.6 22.1 17.3 16.3 15.7 13.6 12.4 24.4 18.9 25.7 38.6 29.6 15.0 19.6 32.1 20.0 12.2 12.2 23.2 7.7 14.5 19.4 18.7 18.9 24.6 31.2 22.7 17.3 17.5 19.8 21.8 22.2 34.6 22.7 16.2 24.2 24.7 11.0 15.7 13.2 48.0 16.0 13.5 27.7 15.7 22.2 22.1 45.5 14.0 19.0 30.5 21.9 29.7 28.4 31.2 18.6 37.7 38.8 36.6 7.7 21.2 22.3 38.5 0.4 0.2 0.3 0.3 0.1 0.3 0.1 0.2 0.2 0.1 0.2 0.2 0.2 0.5 0.2 0.1 0.2 0.2 0.1 8.2 9.5 17.4 10.7 9.7 7.0 6.9 8.1 6.9 7.3 7.9 11.1 50.1 38.5 40.9 17.0 20.1 69.8 39.5 21.5 35.9 65.3 40.1 29.6 19.8 27.1 28.1 18.4 33.3 19.0 38.9 19.1 9.8 19.6 21.3 45.4 59.1 41.7 20.4 9.2 24.0 22.5 12.0 26.9 23.9 53.7 36.8 33.0 36.0 14.6 16.4 53.8 23.9 18.1 30.5 25.7 108.3 16.9 20.8 53.8 17.8 20.6 21.9 40.2 21.6 18.6 42.4 28.9 12.3 19.9 16.0 46.0 13.5 12.0 28.3 57.0 46.0 61.0 44.6 25.6 11.8 43.4 86.1 18.9 23.8 21.6 23.3 44.1 RAB10 ENSG00000084733 "RAB10, member RAS oncogene family" P61026 2 26034084-26137454 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 488.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045611 Approved NA Yes 4300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA045611: AB_10961124" "unprognostic (7.73e-3)" "unprognostic (2.45e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (7.40e-4)" "unprognostic (8.22e-3)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.99e-5)" "unprognostic (9.22e-3)" "unprognostic (6.14e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (7.37e-5)" "unprognostic (1.06e-2)" "unprognostic (8.69e-3)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.99e-2)" 47.4 51.5 42.8 44.2 49.0 17.7 45.1 48.7 56.7 55.6 29.7 58.8 41.3 38.9 40.3 172.9 39.6 41.9 49.8 41.2 47.3 56.8 48.5 39.9 42.8 52.9 46.9 37.1 37.7 66.3 21.5 40.9 54.4 42.6 57.9 29.0 51.7 41.6 213.9 71.0 46.3 48.1 51.5 44.4 58.8 24.0 46.4 43.8 54.2 114.0 64.5 78.5 78.1 62.8 117.1 139.7 63.8 53.1 131.2 108.2 61.9 90.3 76.8 69.7 61.6 83.2 83.8 77.9 83.4 96.7 79.5 62.0 77.3 84.4 73.9 82.3 56.0 135.1 54.4 134.8 122.6 112.2 73.5 89.0 135.9 85.9 100.3 109.6 89.0 48.9 114.1 76.7 95.1 52.0 69.1 87.1 65.2 139.5 81.7 65.2 133.4 132.8 141.6 111.8 90.1 83.7 75.2 135.1 94.9 70.5 59.5 80.1 110.2 107.1 56.2 75.7 97.2 50.5 84.2 124.4 107.9 132.6 83.5 58.0 75.5 35.5 31.5 135.2 38.6 33.4 36.9 34.1 69.9 32.0 31.1 35.2 54.6 50.6 152.6 24.3 44.6 81.0 42.8 49.0 48.7 56.7 41.2 47.3 52.9 46.9 54.4 51.5 46.4 62.8 70.8 80.1 49.7 37.9 56.2 341.8 195.5 156.4 122.3 23.8 85.2 64.6 76.4 85.8 134.7 92.0 8.4 121.0 48.7 168.8 115.4 188.3 35.5 67.8 76.7 78.4 65.2 101.0 43.6 96.0 204.4 80.7 97.3 98.3 50.7 44.0 53.2 66.8 159.7 26.9 36.0 94.1 107.8 157.2 285.1 29.6 62.7 151.6 88.9 36.5 246.8 104.9 38.1 47.7 78.1 136.8 123.8 70.0 63.6 199.7 85.9 135.2 107.4 32.7 85.5 94.1 159.5 85.3 73.4 255.9 488.0 128.3 59.3 65.6 117.7 334.3 RAB11B H-YPT3 ENSG00000185236 "RAB11B, member RAS oncogene family" Q15907 19 8389981-8404434 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 334.5" "Low region specificity" "Detected in all" HPA054396 Approved "Vesicles,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" "Vesicles, Centriolar satellite" "HPA054396: AB_2682474" "unprognostic (5.81e-3)" "prognostic favorable (2.08e-4)" "unprognostic (1.13e-2)" "unprognostic (1.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.61e-3)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (4.78e-2)" "prognostic favorable (7.58e-5)" "unprognostic (1.23e-1)" "prognostic favorable (2.06e-4)" "unprognostic (3.66e-1)" "unprognostic (3.87e-1)" "unprognostic (8.85e-2)" "unprognostic (3.29e-3)" 102.1 96.7 97.6 59.2 113.2 68.7 113.8 118.5 131.4 105.3 67.4 99.1 76.5 101.3 23.0 95.2 97.3 51.2 167.9 91.7 102.0 129.3 133.8 98.2 58.8 130.9 121.8 107.6 129.7 49.0 115.7 53.9 127.7 111.7 23.4 38.2 104.3 49.3 119.6 101.8 97.2 27.8 108.1 118.7 118.0 64.5 120.4 44.1 210.0 36.6 28.2 99.5 94.2 127.3 93.1 115.3 83.1 75.9 43.7 39.9 64.8 54.6 36.8 39.5 42.0 79.4 74.3 54.1 147.7 47.3 53.1 70.8 29.4 78.7 13.1 109.3 142.4 57.5 97.8 98.0 42.4 67.6 102.6 59.5 49.1 44.6 29.6 51.2 50.1 71.7 62.4 137.2 42.2 92.8 116.7 334.5 117.9 44.6 111.3 75.2 56.2 91.0 43.6 130.1 91.4 118.7 67.7 53.8 71.5 33.8 67.9 75.0 98.0 146.2 85.4 114.0 86.2 145.3 101.7 64.1 109.4 75.3 100.6 47.6 44.4 100.7 44.7 45.5 30.6 39.6 40.3 46.8 45.4 41.3 38.1 36.6 65.7 53.7 55.2 59.1 43.0 39.6 97.6 113.2 118.5 131.4 91.7 102.0 130.9 121.8 127.7 108.1 120.4 127.3 74.0 19.2 25.7 21.2 68.3 62.1 86.2 115.1 75.7 60.1 85.0 79.8 18.1 71.4 59.5 95.6 14.6 152.2 52.4 148.4 127.2 93.8 44.3 58.2 43.2 70.7 114.7 63.1 15.1 94.9 166.7 71.3 99.4 51.0 29.9 56.5 76.1 62.2 109.6 67.3 18.7 112.4 118.0 62.8 52.7 38.0 86.3 62.6 71.2 15.9 76.9 104.1 59.8 8.5 41.3 82.3 154.7 76.3 78.0 81.1 135.5 113.9 59.3 36.0 92.1 50.1 121.0 64.5 38.7 69.8 69.3 209.9 63.3 46.4 92.8 104.6 RAB14 "FBP, RAB-14" ENSG00000119396 "RAB14, member RAS oncogene family" P61106 9 121178133-121223014 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026419, CAB037066" Approved Supported Vesicles NA NA 2700000 "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB037066: AB_1841128, HPA026419: AB_1855996" "unprognostic (1.30e-3)" "unprognostic (3.12e-2)" "unprognostic (9.01e-2)" "unprognostic (7.18e-2)" "unprognostic (6.53e-2)" "unprognostic (3.00e-1)" "unprognostic (1.39e-1)" "unprognostic (1.18e-1)" "unprognostic (2.52e-1)" "unprognostic (6.90e-2)" "unprognostic (3.05e-2)" "unprognostic (9.71e-3)" "prognostic favorable (1.79e-8)" "unprognostic (1.38e-1)" "unprognostic (3.17e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" 39.0 38.7 37.5 35.6 39.7 66.5 42.1 40.3 47.7 37.8 32.6 42.8 39.9 35.6 34.2 63.2 34.0 30.7 32.4 38.4 40.9 50.0 82.8 49.2 41.1 39.6 39.9 35.9 27.6 45.8 28.9 43.1 40.5 38.8 42.4 45.5 34.6 38.1 39.4 56.4 38.9 33.4 40.8 38.3 44.3 33.8 40.2 35.2 43.8 38.9 49.5 43.9 40.8 46.8 53.8 53.7 66.9 56.3 76.2 82.5 52.6 74.8 59.6 56.6 44.7 42.6 57.0 51.2 42.5 72.0 49.2 100.1 48.1 55.8 63.6 44.4 31.7 55.7 69.0 43.9 52.6 60.1 63.8 53.0 98.5 58.2 63.4 62.5 81.2 47.1 42.8 45.6 85.6 50.8 58.5 48.1 39.7 104.8 59.9 45.8 72.3 60.4 62.3 76.0 58.9 34.4 89.0 78.0 53.8 47.1 82.1 46.8 76.0 60.1 43.9 75.3 53.0 40.8 82.6 52.3 56.6 51.9 80.7 34.4 29.4 33.5 22.4 41.5 22.4 24.6 20.9 24.7 31.4 23.4 24.6 25.0 31.8 26.5 43.7 19.0 29.3 24.0 37.5 39.7 40.3 47.7 38.4 40.9 39.6 39.9 40.5 40.8 40.2 46.8 102.6 160.3 103.9 23.5 64.4 157.9 78.2 84.8 97.3 93.8 70.7 58.8 39.2 62.9 96.2 62.5 37.5 85.2 79.6 95.1 86.1 81.3 41.9 80.7 89.8 84.5 60.3 44.4 42.5 64.4 83.0 68.7 64.7 94.4 77.2 58.1 61.1 113.6 91.0 94.2 38.0 59.8 95.6 89.9 105.4 36.2 51.9 80.7 110.3 44.0 84.8 100.5 49.4 38.2 59.0 80.7 52.9 56.4 50.2 81.0 63.2 103.3 86.8 62.0 59.2 64.0 105.6 112.9 113.6 120.0 202.4 116.2 74.3 82.5 64.0 106.0 RABEP1 "neurocrescin, RAB5EP, rabaptin-5, RABPT5" ENSG00000029725 "Rabaptin, RAB GTPase binding effector protein 1" Q15276 17 5282265-5386340 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004549, HPA019669, HPA024235, HPA024691" Supported Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004549: AB_628192, HPA019669: AB_1856019, HPA024235: AB_1856020, HPA024691: AB_1856021" "unprognostic (3.22e-1)" "unprognostic (2.90e-2)" "unprognostic (2.45e-1)" "unprognostic (8.75e-3)" "unprognostic (1.64e-1)" "unprognostic (8.25e-2)" "unprognostic (3.71e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (7.73e-2)" "prognostic favorable (6.43e-4)" "unprognostic (1.14e-1)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" "unprognostic (1.00e-1)" "unprognostic (9.00e-3)" 30.1 23.6 39.1 23.2 45.8 17.1 43.9 41.0 49.3 22.2 32.0 21.1 16.5 26.8 25.1 18.5 16.7 21.7 32.4 37.9 46.7 23.5 32.8 19.5 33.5 43.1 44.8 21.7 18.0 48.0 19.7 30.8 44.2 31.0 20.7 58.2 22.7 21.8 68.5 16.3 18.9 27.5 43.5 28.3 24.0 18.8 43.7 37.3 25.8 52.4 40.3 23.1 15.2 50.7 45.5 57.5 59.6 33.3 60.9 60.5 31.2 58.3 44.5 61.8 58.5 51.4 19.7 98.3 46.0 61.2 35.0 35.9 87.8 50.0 86.4 60.7 75.0 60.9 73.1 39.4 56.4 41.3 37.9 47.2 33.3 59.6 76.5 37.7 54.4 49.9 52.3 48.3 54.2 32.7 66.1 30.4 26.8 25.8 24.9 61.2 70.8 32.4 30.6 43.1 25.3 39.4 52.4 52.8 49.5 52.3 95.9 17.2 46.9 53.1 24.2 52.6 69.6 26.9 31.0 52.4 41.2 62.3 37.5 14.9 21.1 22.4 25.0 22.7 21.9 80.4 19.5 24.0 22.6 96.7 24.6 21.5 30.4 22.6 50.9 35.0 20.0 16.6 39.1 45.8 41.0 49.3 37.9 46.7 43.1 44.8 44.2 43.5 43.7 50.7 36.4 35.3 45.1 57.5 53.8 24.0 30.1 17.0 25.6 51.5 87.3 46.0 91.1 14.3 32.9 18.4 39.6 39.7 47.2 18.6 41.1 30.4 7.6 19.8 55.5 37.9 16.3 58.3 123.7 23.8 35.0 38.5 23.4 25.3 12.6 47.0 34.2 31.7 89.8 35.3 115.9 17.1 30.5 32.1 38.2 6.0 33.8 36.5 30.2 90.9 32.8 89.7 63.8 78.4 114.1 28.3 65.5 28.2 28.2 52.8 16.5 38.1 19.0 52.5 26.3 34.3 47.7 82.2 75.7 25.5 20.3 25.9 34.4 61.2 18.9 33.6 RALA RAL ENSG00000006451 "RAS like proto-oncogene A" P11233 7 39623565-39708120 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Exocytosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 292.4;Pancreatic endocrine cells: 411.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 302.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047037, HPA065232" Approved Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "Focal adhesion sites" "HPA047037: , HPA065232: AB_2685440" "unprognostic (1.20e-3)" "unprognostic (1.03e-2)" "unprognostic (2.91e-1)" "unprognostic (7.73e-3)" "unprognostic (1.98e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (7.71e-2)" "unprognostic (2.17e-1)" "prognostic favorable (7.46e-4)" "prognostic unfavorable (6.30e-4)" "unprognostic (3.32e-1)" "unprognostic (4.95e-3)" "unprognostic (5.38e-2)" "unprognostic (7.15e-2)" "unprognostic (2.79e-1)" "unprognostic (2.95e-2)" 27.8 32.1 32.4 20.7 35.5 7.4 23.8 35.8 37.3 23.0 30.2 30.9 32.6 20.4 20.1 54.0 19.6 26.8 17.6 33.7 34.3 20.6 21.4 41.8 21.4 37.0 35.7 22.2 16.0 22.6 10.5 32.5 36.4 15.4 31.6 13.0 19.8 15.8 25.8 26.9 30.9 21.1 37.7 18.8 33.8 12.7 34.9 25.5 17.4 19.1 35.2 23.5 22.0 39.8 81.0 18.3 44.1 38.6 81.7 67.6 30.0 69.7 99.7 61.8 67.9 46.1 39.0 41.5 25.5 54.1 58.1 81.5 62.5 45.0 105.5 40.2 29.6 32.4 28.1 34.1 132.1 56.9 43.8 53.7 54.0 110.0 155.4 76.7 302.4 39.7 65.9 27.0 63.2 26.3 40.3 66.7 123.0 88.0 35.9 49.4 40.2 36.3 63.1 37.3 78.0 75.6 42.8 67.7 49.4 78.7 63.5 60.9 98.0 36.4 32.4 46.3 50.7 47.6 39.1 50.3 40.5 58.0 67.2 38.3 13.5 15.7 12.5 15.6 15.7 15.8 20.1 16.2 22.6 18.0 25.6 22.9 6.1 23.2 12.6 14.5 28.1 15.9 32.4 35.5 35.8 37.3 33.7 34.3 37.0 35.7 36.4 37.7 34.9 39.8 66.5 83.3 38.1 25.5 40.5 90.1 37.3 75.1 41.5 14.6 41.3 63.5 37.3 40.0 50.3 23.9 6.2 52.1 28.4 80.1 21.5 165.4 98.2 56.5 64.8 121.5 47.8 35.1 47.6 122.0 92.5 52.4 42.3 99.9 31.7 41.8 75.0 27.8 101.9 11.8 48.4 53.1 144.5 33.0 292.4 17.4 47.8 73.0 30.2 44.0 97.0 37.3 23.7 39.2 37.0 411.0 73.8 69.6 48.6 61.0 70.8 38.6 36.6 16.6 32.9 26.5 131.9 59.1 71.6 113.4 109.4 62.0 37.0 53.9 58.7 64.5 RAN "ARA24, Gsp1, TC4" ENSG00000132341 "RAN, member RAS oncogene family" P62826 12 130872037-130877678 "Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Host-virus interaction, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA063353 Enhanced Nucleoplasm No No 4000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA063353: " "unprognostic (2.22e-2)" "unprognostic (5.16e-2)" "unprognostic (2.30e-2)" "unprognostic (3.34e-2)" "unprognostic (1.75e-1)" "unprognostic (3.39e-3)" "prognostic unfavorable (9.99e-8)" "unprognostic (2.81e-3)" "unprognostic (1.28e-1)" "unprognostic (5.41e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (7.86e-5)" "prognostic unfavorable (1.46e-7)" "unprognostic (6.55e-2)" "unprognostic (2.79e-1)" "unprognostic (4.62e-1)" "unprognostic (3.16e-2)" 285.3 333.2 207.7 340.1 222.3 406.0 220.5 212.1 265.0 193.6 204.5 269.1 177.8 207.6 238.1 445.6 180.6 148.9 256.9 220.6 260.3 249.0 208.2 225.9 416.4 207.2 213.3 180.7 192.9 210.6 180.1 243.0 231.0 149.7 266.6 213.3 200.4 155.5 415.0 231.2 220.0 250.1 228.5 255.9 223.4 308.6 236.5 577.6 166.8 383.7 480.6 380.9 244.7 230.2 1391.5 1850.5 1580.8 921.6 707.0 868.2 1219.5 1770.2 926.2 1695.1 1163.1 2003.5 1434.2 2260.7 1169.3 1290.0 1067.9 877.0 2327.1 1854.5 1830.8 766.9 1831.5 1331.9 1318.9 2068.9 864.1 2347.9 1100.3 821.9 1129.3 1470.6 2111.6 1119.9 1671.0 1593.5 2013.6 656.5 1686.3 1688.2 2306.9 2810.1 1857.8 1429.2 2936.2 1773.9 1347.2 1274.4 1608.2 2377.1 1441.5 875.0 1018.5 920.7 1334.4 1299.9 1817.9 1666.5 1157.6 975.6 1495.0 998.8 1694.1 905.2 1605.1 3245.4 1002.2 1410.7 1390.4 285.0 398.0 275.5 501.5 489.3 614.6 726.4 682.5 581.4 531.7 593.3 611.5 585.9 80.7 500.4 481.0 506.9 768.0 1005.0 207.7 222.3 212.1 265.0 220.6 260.3 207.2 213.3 231.0 228.5 236.5 230.2 321.3 182.7 141.5 18.6 337.4 635.3 693.4 702.0 406.3 155.3 239.0 316.0 112.6 165.8 310.5 169.2 37.5 734.2 273.6 157.0 387.4 642.1 90.2 212.9 280.8 306.2 201.9 540.9 27.8 452.8 1266.0 379.6 181.0 201.3 194.0 273.1 143.8 181.6 624.5 139.7 25.8 300.5 349.9 171.7 424.1 148.1 213.4 239.7 332.6 9.4 417.0 287.5 219.4 19.6 23.5 596.4 189.1 230.9 418.2 954.8 167.2 423.2 214.3 141.6 164.3 286.0 600.8 746.4 571.6 578.0 547.0 613.1 332.3 451.9 403.6 621.0 RANBP1 HTF9A ENSG00000099901 "RAN binding protein 1" P43487 22 20115938-20127355 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 754.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 2431.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065868, HPA065931" Supported Enhanced Cytosol NA NA 1400000 "Cluster 26: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA065868: AB_2685572, HPA065931: AB_2685580" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "unprognostic (4.43e-3)" "unprognostic (6.55e-3)" "unprognostic (4.35e-2)" "unprognostic (2.50e-2)" "prognostic unfavorable (1.58e-6)" "unprognostic (2.83e-2)" "unprognostic (2.21e-2)" "unprognostic (5.67e-3)" "unprognostic (1.54e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.40e-2)" "unprognostic (3.95e-1)" "unprognostic (4.44e-2)" "unprognostic (7.30e-2)" 65.5 68.0 37.6 63.3 38.6 117.5 60.7 40.2 47.9 67.1 28.8 63.9 52.9 66.7 21.4 94.7 61.2 30.0 47.5 39.7 40.5 64.8 86.7 53.5 94.7 41.1 39.1 61.0 54.0 35.9 50.3 46.2 41.4 49.8 42.9 35.3 51.8 34.3 54.9 61.8 60.6 36.2 40.8 71.1 55.5 117.8 39.6 104.0 46.5 34.8 72.6 61.9 64.7 43.7 434.6 218.5 479.7 263.2 79.1 93.8 403.7 388.7 169.3 494.6 356.4 401.5 150.8 669.8 169.7 157.8 224.9 394.2 449.4 340.4 269.6 290.1 1071.3 562.6 218.5 426.6 120.3 913.7 294.4 103.9 158.7 393.0 139.2 114.3 227.1 300.2 2431.9 261.1 226.8 339.2 665.5 622.0 547.2 553.8 380.8 667.4 674.7 172.6 171.6 233.9 478.6 354.7 356.6 196.4 236.6 210.3 137.1 378.9 176.4 341.5 668.1 258.7 438.3 260.9 383.6 1066.0 186.9 405.9 292.7 21.1 94.7 75.8 71.3 101.6 78.8 123.1 101.6 91.1 111.5 119.1 101.8 77.0 9.5 90.8 93.6 103.6 115.4 102.5 37.6 38.6 40.2 47.9 39.7 40.5 41.1 39.1 41.4 40.8 39.6 43.7 133.1 35.3 37.1 14.7 135.0 274.4 195.0 260.6 109.3 44.4 142.3 175.6 47.1 104.4 104.8 90.1 6.2 409.2 103.8 106.4 277.8 188.5 394.2 104.6 131.1 143.5 117.6 259.2 22.2 112.3 754.9 156.7 72.4 86.7 64.7 187.2 93.5 169.5 268.7 37.0 21.4 194.0 209.5 85.5 223.3 236.1 145.1 95.3 177.9 6.5 140.6 103.5 87.6 7.5 23.9 150.0 109.3 136.9 179.6 338.0 107.3 213.7 93.8 39.0 98.6 110.9 289.5 505.1 435.2 220.1 294.9 194.7 119.2 176.5 273.6 218.2 RAP1A "KREV-1, SMGP21" ENSG00000116473 "RAP1A, member of RAS oncogene family" P62834 1 111542218-111716691 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" Neurogenesis Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 494.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (7.37e-3)" "unprognostic (7.49e-2)" "unprognostic (1.40e-2)" "unprognostic (1.59e-1)" "unprognostic (1.13e-1)" "unprognostic (6.88e-2)" "unprognostic (1.57e-3)" "unprognostic (9.89e-2)" "unprognostic (6.10e-2)" "unprognostic (4.98e-3)" "unprognostic (1.54e-2)" "unprognostic (1.84e-1)" "unprognostic (3.44e-2)" "unprognostic (1.06e-1)" "unprognostic (1.76e-1)" "unprognostic (3.76e-1)" "unprognostic (3.08e-1)" 91.6 59.9 45.4 101.8 55.6 81.4 57.5 55.4 71.1 52.2 41.6 160.2 67.8 53.8 82.2 107.5 51.6 63.3 93.9 42.9 52.1 70.8 98.1 77.3 114.0 57.7 53.3 41.3 36.0 123.4 32.9 65.5 59.5 67.9 94.4 26.9 66.3 96.4 89.4 38.7 75.1 89.5 56.3 89.5 78.9 17.9 49.9 76.7 65.2 86.6 123.6 100.8 45.4 67.9 162.8 25.1 61.1 36.1 121.7 116.7 56.5 105.7 112.2 75.0 84.4 83.3 65.9 132.0 72.5 133.1 48.2 57.6 56.5 79.4 138.9 494.7 58.7 96.0 61.4 51.9 124.0 101.4 95.7 76.0 90.9 83.5 86.8 69.7 100.3 73.9 73.8 142.3 104.6 74.4 52.7 128.0 36.2 72.1 66.5 56.9 129.4 65.9 120.2 80.9 43.3 30.8 129.9 75.6 99.3 61.9 38.3 127.9 94.5 60.2 77.2 76.2 104.4 151.2 54.7 145.4 83.9 152.7 161.1 15.6 22.1 21.1 17.0 23.6 20.0 16.4 29.0 25.9 26.2 10.6 21.5 20.9 48.4 22.1 21.6 13.0 29.0 19.0 45.4 55.6 55.4 71.1 42.9 52.1 57.7 53.3 59.5 56.3 49.9 67.9 107.5 67.3 83.1 36.2 104.8 123.9 103.5 65.2 31.9 17.4 49.3 33.1 122.6 41.5 60.0 46.0 4.2 70.5 117.8 134.2 158.5 73.4 28.1 27.6 39.9 118.4 40.8 149.7 73.1 69.8 76.1 78.4 56.6 38.8 85.6 24.8 97.1 60.3 209.2 50.5 78.1 130.8 46.8 245.4 265.5 14.4 63.3 193.6 101.4 182.7 179.7 71.4 148.3 62.4 203.4 74.9 88.3 78.2 119.2 125.1 104.7 133.8 40.4 11.7 118.3 80.5 141.5 26.0 10.9 42.1 101.7 82.1 168.3 89.6 84.0 152.7 RAP1B "DKFZp586H0723, K-REV, RAL1B" ENSG00000127314 "RAP1B, member of RAS oncogene family" P61224 12 68610855-68671901 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.20e-1)" "unprognostic (1.47e-3)" "unprognostic (1.11e-1)" "unprognostic (1.20e-1)" "unprognostic (4.15e-2)" "unprognostic (7.23e-2)" "unprognostic (1.60e-3)" "unprognostic (1.48e-1)" "unprognostic (5.83e-2)" "unprognostic (1.80e-1)" "unprognostic (2.01e-2)" "unprognostic (2.86e-1)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.08e-1)" "unprognostic (8.86e-2)" "unprognostic (7.86e-2)" "unprognostic (3.22e-1)" 156.1 107.5 48.2 166.5 53.4 277.9 118.2 55.8 64.2 89.8 62.5 126.4 84.2 120.2 69.7 86.3 78.7 129.7 67.9 49.5 60.0 107.3 141.1 134.9 211.8 58.3 53.5 69.3 78.8 74.1 52.0 133.0 59.7 85.1 111.5 57.6 70.0 135.9 49.5 73.5 121.0 146.4 52.4 153.3 104.4 89.6 55.6 162.5 89.1 57.3 181.1 198.1 83.8 66.2 199.9 133.1 153.2 131.2 317.6 253.1 140.2 414.9 252.1 269.5 203.5 178.9 130.2 280.0 232.8 580.5 124.2 113.4 146.5 202.9 379.8 496.2 125.7 725.2 156.7 120.9 370.8 282.0 407.1 254.8 203.3 289.5 346.0 218.6 298.7 232.1 261.2 445.6 272.0 127.9 265.4 361.7 173.9 86.8 191.3 235.8 181.9 211.1 204.9 488.3 59.6 93.3 209.1 124.8 206.1 174.7 160.3 327.2 330.4 243.0 108.9 275.6 229.9 227.1 452.4 342.3 224.7 191.8 212.3 399.1 215.4 205.7 340.1 407.0 221.2 154.1 206.1 297.6 196.2 140.3 222.2 303.4 149.8 469.5 464.3 99.0 186.2 820.8 48.2 53.4 55.8 64.2 49.5 60.0 58.3 53.5 59.7 52.4 55.6 66.2 210.9 80.1 79.9 41.1 166.2 294.4 72.4 150.9 70.6 14.0 73.3 61.0 14.7 37.1 108.9 80.9 22.9 35.5 373.9 176.1 109.5 157.9 99.6 78.5 154.3 132.4 189.5 104.7 45.0 130.8 75.2 123.4 52.0 119.6 147.8 60.5 85.3 32.7 78.5 33.7 46.8 93.5 95.6 111.3 437.6 44.6 38.8 273.1 188.5 105.9 257.3 28.6 362.5 45.8 67.8 186.0 215.6 36.5 228.4 61.4 72.3 182.2 104.0 23.3 6.6 40.3 204.8 46.3 50.2 78.9 297.8 154.5 256.9 123.2 92.2 92.4 RBM17 "MGC14439, SPF45" ENSG00000134453 "RNA binding motif protein 17" Q96I25 10 6089034-6117457 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037477, HPA037478" Supported Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA037477: AB_10671372, HPA037478: AB_2675494" "unprognostic (8.55e-2)" "unprognostic (2.41e-1)" "unprognostic (3.11e-3)" "unprognostic (6.23e-2)" "unprognostic (1.05e-2)" "unprognostic (3.33e-2)" "prognostic unfavorable (4.57e-8)" "unprognostic (3.78e-2)" "unprognostic (6.39e-2)" "unprognostic (3.47e-3)" "unprognostic (1.44e-1)" "unprognostic (8.32e-2)" "prognostic unfavorable (4.31e-5)" "unprognostic (1.82e-1)" "unprognostic (5.53e-2)" "unprognostic (1.26e-2)" "unprognostic (3.01e-2)" 72.4 47.0 46.3 75.3 51.6 139.5 64.4 47.2 53.5 50.2 40.1 57.6 63.8 63.5 38.7 51.9 55.3 52.6 60.8 46.9 52.3 54.6 44.6 78.0 87.4 53.5 49.5 54.7 62.9 45.5 35.8 75.7 52.7 41.5 65.2 41.6 49.9 39.4 95.4 47.0 70.5 60.4 47.3 77.6 51.6 61.9 52.5 87.7 63.3 72.1 85.4 63.5 49.4 52.4 195.9 113.0 141.1 122.7 76.5 69.4 175.5 128.4 58.0 130.2 139.8 184.7 151.2 234.1 89.3 94.4 48.5 188.1 130.3 136.4 138.6 233.7 132.1 199.3 120.4 158.5 96.7 110.0 93.6 71.7 104.0 132.4 72.4 67.9 159.6 168.1 219.0 112.1 84.1 223.6 198.8 66.2 90.3 227.8 81.3 211.4 79.9 120.8 93.5 117.3 60.5 78.9 124.1 110.1 99.0 119.5 146.3 111.3 97.3 76.9 153.4 169.0 138.1 110.2 135.6 386.7 72.0 140.3 51.7 79.7 78.2 102.6 71.6 79.0 75.2 101.8 71.8 73.4 69.9 110.2 71.8 68.1 38.7 77.8 62.3 77.0 101.1 59.8 46.3 51.6 47.2 53.5 46.9 52.3 53.5 49.5 52.7 47.3 52.5 52.4 152.3 89.8 56.0 24.8 107.7 129.2 97.4 72.7 108.7 71.3 68.5 85.3 86.0 65.8 68.1 66.2 50.1 125.6 83.3 80.8 90.1 92.0 90.2 74.7 99.5 123.9 72.7 100.5 42.2 70.9 188.5 89.5 58.6 83.9 96.8 79.7 69.7 65.3 98.8 92.5 41.4 87.1 63.1 73.6 128.6 26.3 66.2 93.9 51.6 38.4 161.5 77.9 96.8 23.6 40.7 88.0 86.4 60.5 153.8 122.3 79.8 75.7 41.3 62.2 72.3 115.6 117.4 266.4 233.3 114.4 108.7 97.0 97.4 78.9 106.5 112.6 RCE1 "FACE-2, FACE2, hRCE1, RCE1A, RCE1B" ENSG00000173653 "Ras converting CAAX endopeptidase 1" Q9Y256 11 66842835-66846552 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074124 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "HPA074124: " "unprognostic (1.11e-1)" "unprognostic (7.23e-2)" "unprognostic (1.15e-1)" "unprognostic (8.16e-3)" "unprognostic (3.11e-1)" "unprognostic (6.40e-3)" "unprognostic (1.98e-3)" "unprognostic (7.69e-3)" "unprognostic (1.39e-1)" "unprognostic (9.14e-3)" "unprognostic (2.35e-3)" "unprognostic (5.31e-3)" "unprognostic (1.06e-1)" "unprognostic (4.48e-3)" "unprognostic (2.17e-2)" "unprognostic (1.04e-1)" "unprognostic (4.28e-2)" 10.1 10.9 14.9 7.2 15.1 20.9 9.3 17.9 18.2 10.7 13.7 13.3 10.1 8.4 5.9 19.9 8.9 8.6 7.3 14.7 14.9 25.7 7.9 8.9 9.9 14.0 14.1 10.8 15.5 9.5 13.9 11.8 14.2 12.0 8.2 10.0 12.6 6.1 4.4 19.9 12.4 5.9 13.5 12.0 12.0 13.5 15.5 9.5 7.0 4.2 6.1 11.9 12.9 14.6 22.7 24.5 14.7 13.8 9.0 7.8 32.3 11.6 11.2 17.7 15.8 46.6 47.2 17.2 21.8 11.1 29.3 39.6 17.1 17.4 10.2 20.7 19.3 15.5 17.0 18.0 31.7 20.3 22.0 12.6 32.7 19.9 17.6 13.7 14.6 23.5 21.7 26.0 9.0 42.8 28.2 38.3 43.5 43.1 24.0 22.9 11.0 34.1 19.5 12.0 18.3 16.5 16.8 22.3 74.1 14.3 26.2 16.3 9.7 24.2 18.7 26.4 18.5 14.6 15.2 19.6 16.4 20.8 18.4 23.1 21.1 14.6 17.1 24.0 15.6 15.3 14.7 22.1 18.9 12.0 11.8 17.8 7.2 14.3 21.5 29.1 6.7 17.8 14.9 15.1 17.9 18.2 14.7 14.9 14.0 14.1 14.2 13.5 15.5 14.6 12.5 0.0 4.8 4.2 16.9 31.2 26.6 46.2 14.2 9.2 16.4 20.6 1.8 10.0 20.3 16.5 29.2 54.6 24.9 12.4 3.9 24.3 10.1 11.3 12.5 12.2 10.7 10.7 7.7 27.4 65.0 12.0 11.7 17.1 8.2 13.3 8.2 3.0 22.8 3.3 6.2 16.0 26.4 8.9 15.1 20.2 6.8 13.3 14.2 3.7 12.9 6.4 9.2 6.0 4.0 30.0 18.0 6.4 14.5 19.6 23.2 7.4 8.9 18.0 13.1 5.6 32.1 9.7 25.7 17.1 24.9 58.6 19.1 10.3 16.2 23.9 REEP5 "C5orf18, D5S346, DP1, POB16, TB2, Yip2e" ENSG00000129625 "Receptor accessory protein 5" Q00765 5 112876385-112922289 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003895, HPA069960" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA069960: AB_2686221" "unprognostic (3.26e-3)" "unprognostic (2.60e-1)" "unprognostic (2.71e-1)" "prognostic favorable (5.23e-6)" "unprognostic (8.29e-2)" "unprognostic (1.44e-2)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (2.85e-1)" "unprognostic (3.75e-2)" "unprognostic (7.75e-2)" "unprognostic (5.90e-2)" "prognostic favorable (2.05e-5)" "unprognostic (2.88e-2)" "unprognostic (4.14e-2)" "unprognostic (1.83e-1)" "unprognostic (3.24e-2)" 76.9 105.4 97.1 50.5 100.2 27.3 130.6 92.7 120.7 87.1 76.8 66.6 56.8 58.4 120.0 52.1 64.7 60.8 133.2 107.3 110.5 148.0 124.3 80.4 48.2 112.2 104.8 72.2 123.0 140.7 41.5 66.6 115.2 98.9 58.1 81.5 147.7 84.2 114.3 59.1 58.1 55.0 96.4 54.3 70.2 28.3 120.0 32.1 239.4 99.6 56.7 73.2 49.1 98.3 101.7 90.9 29.7 72.5 136.0 115.9 104.7 102.2 92.6 96.4 103.4 74.9 138.1 42.5 179.6 105.1 112.5 107.5 66.8 138.9 88.5 190.6 116.4 42.8 56.3 63.5 126.8 36.9 77.4 81.3 136.0 82.2 78.0 94.5 113.7 38.7 26.0 84.5 121.3 100.0 15.7 60.7 43.4 73.5 75.3 22.4 84.3 116.6 229.1 108.4 56.9 43.1 148.5 244.6 99.8 75.5 287.3 58.9 142.4 83.4 32.0 126.5 126.4 97.6 126.2 33.8 142.6 65.4 47.8 224.4 222.9 234.3 140.1 249.5 149.4 175.7 112.7 133.9 189.0 149.2 52.5 94.6 253.0 112.7 316.2 133.6 177.9 236.4 97.1 100.2 92.7 120.7 107.3 110.5 112.2 104.8 115.2 96.4 120.0 98.3 141.2 166.7 102.3 30.0 131.1 93.0 177.7 291.6 89.4 83.5 225.3 188.1 217.3 145.8 213.7 195.0 89.6 296.0 138.4 77.0 82.2 275.1 231.5 111.8 97.0 130.5 118.0 34.9 78.6 414.1 352.8 182.3 65.7 141.6 108.9 76.0 118.2 197.0 267.1 87.5 95.0 127.5 256.3 135.0 159.9 42.0 116.2 168.8 206.3 36.5 188.6 97.2 101.0 44.7 71.5 316.5 141.1 133.9 271.6 225.3 134.1 146.1 170.6 80.0 111.7 92.6 253.0 162.8 63.9 118.1 101.6 489.8 123.7 100.3 104.5 214.8 RER1 ENSG00000157916 "Retention in endoplasmic reticulum sorting receptor 1" O15258 1 2391775-2405442 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037240, HPA051400" Supported Supported "Golgi apparatus" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" "CAB037240: AB_2179604, HPA051400: AB_2681469" "unprognostic (2.90e-2)" "unprognostic (3.35e-2)" "unprognostic (3.17e-2)" "unprognostic (2.59e-2)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (1.53e-2)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.14e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.23e-8)" "unprognostic (1.01e-1)" "unprognostic (5.41e-2)" "unprognostic (1.06e-1)" "unprognostic (3.27e-2)" 100.4 154.2 60.0 89.3 67.6 81.6 97.1 67.0 62.8 93.6 78.3 137.4 114.8 74.4 122.7 176.4 86.1 86.9 75.7 61.1 64.1 106.3 224.8 79.6 94.6 67.0 65.1 92.9 122.3 100.9 82.9 99.0 66.9 94.3 151.4 73.8 101.1 104.2 105.2 101.7 120.0 104.6 65.6 102.2 118.6 107.1 68.5 94.5 85.9 85.1 143.5 101.0 106.5 76.1 203.1 111.0 131.1 146.8 233.7 275.7 100.9 297.1 261.1 254.3 253.2 157.6 299.3 143.9 242.7 297.7 205.1 213.3 152.2 176.7 322.2 180.8 156.1 163.9 247.2 153.0 252.5 181.3 188.6 225.0 176.1 264.3 233.1 175.4 235.8 160.3 197.8 232.6 299.8 141.5 127.2 127.3 87.5 314.1 279.0 146.0 131.9 183.7 227.5 94.3 109.9 126.2 167.9 376.9 242.9 143.7 149.6 127.4 171.8 197.3 114.1 355.9 219.5 223.0 270.2 255.3 209.6 254.8 102.8 239.1 235.5 284.5 195.9 268.2 180.0 169.0 169.8 210.0 221.2 151.7 127.0 155.9 351.3 164.8 275.9 256.1 244.5 309.0 60.0 67.6 67.0 62.8 61.1 64.1 67.0 65.1 66.9 65.6 68.5 76.1 88.7 64.1 50.0 23.5 73.1 53.2 84.4 214.2 50.1 33.6 111.9 123.6 41.6 118.7 131.4 104.8 33.3 233.8 97.5 218.9 66.5 213.4 475.6 89.5 93.5 68.2 36.5 57.2 16.7 258.4 321.8 94.3 71.9 118.8 44.3 76.5 82.1 233.5 217.9 37.0 16.8 158.6 122.1 104.3 73.2 464.0 82.6 99.9 62.2 15.9 126.1 97.0 114.4 19.1 25.8 256.4 195.4 76.0 145.1 142.5 238.7 119.6 136.3 62.6 111.7 60.9 141.6 291.4 145.2 103.4 67.1 467.9 74.3 159.0 162.0 141.0 RFC3 "MGC5276, RFC38" ENSG00000133119 "Replication factor C subunit 3" P40938 13 33818069-33966558 "Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 285.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030149 Approved Supported Nucleoplasm,Vesicles No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 63: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Vesicles" "HPA030149: AB_10602921" "unprognostic (3.86e-2)" "unprognostic (5.27e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-2)" "unprognostic (5.76e-2)" "unprognostic (3.07e-3)" "unprognostic (3.32e-2)" "unprognostic (4.93e-2)" "unprognostic (9.02e-3)" "unprognostic (4.49e-1)" "unprognostic (6.46e-2)" "unprognostic (4.05e-2)" "unprognostic (5.24e-3)" "unprognostic (4.05e-2)" "unprognostic (1.79e-1)" "unprognostic (5.08e-2)" "unprognostic (2.86e-1)" 5.3 13.8 2.6 12.9 2.4 19.5 12.8 8.7 2.6 5.7 1.7 9.0 8.5 10.6 4.3 6.7 8.3 4.6 6.1 2.7 2.5 5.1 7.4 5.4 24.3 2.7 2.2 7.8 4.8 5.1 2.6 10.8 2.8 6.3 11.6 5.9 5.5 4.1 3.5 7.5 7.9 7.6 3.7 6.6 6.5 12.8 2.6 24.1 6.5 4.4 23.4 5.7 4.6 2.5 49.0 51.1 86.4 69.5 6.5 10.0 47.5 66.6 29.2 85.5 73.7 63.0 72.2 179.8 26.8 25.3 53.2 72.5 111.6 45.9 112.0 71.5 68.9 105.0 54.4 68.0 7.5 127.2 48.3 9.8 5.8 74.5 49.9 14.1 28.9 63.7 75.1 44.2 51.4 56.1 108.8 58.1 104.2 101.2 42.1 40.3 103.4 41.1 25.4 42.7 45.1 79.2 49.4 65.3 33.4 45.7 52.2 66.8 15.5 45.1 49.7 57.1 70.9 24.9 36.7 285.3 32.4 73.7 86.6 1.5 4.4 7.2 3.2 6.1 3.7 5.8 3.9 3.3 6.1 5.5 5.0 4.5 0.9 2.5 5.3 2.5 6.3 3.1 2.6 2.4 8.7 2.6 2.7 2.5 2.7 2.2 2.8 3.7 2.6 2.5 9.3 9.6 6.2 5.9 11.2 12.2 6.9 6.9 7.4 16.5 8.9 10.5 7.5 1.5 8.6 3.7 8.4 29.6 5.1 3.0 3.9 7.3 8.4 7.0 7.9 9.4 6.1 43.8 30.2 8.9 39.3 7.5 3.1 7.7 1.3 17.8 8.9 7.2 11.9 8.4 20.3 4.3 4.1 6.7 4.0 7.9 6.2 6.5 8.8 34.7 6.4 5.4 1.0 33.7 18.0 5.4 1.5 4.5 21.0 2.7 1.1 5.4 3.8 12.2 6.6 7.9 29.8 52.6 43.2 9.2 7.0 16.4 6.6 9.2 10.1 3.3 RHEB RHEB2 ENSG00000106615 "Ras homolog, mTORC1 binding" Q15382 7 151466012-151520120 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 724.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019436 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "CAB019436: AB_2178777" "unprognostic (2.22e-2)" "unprognostic (2.29e-2)" "unprognostic (2.25e-2)" "unprognostic (9.47e-2)" "unprognostic (2.65e-2)" "unprognostic (3.08e-3)" "prognostic unfavorable (9.08e-5)" "unprognostic (9.37e-2)" "unprognostic (4.76e-3)" "unprognostic (9.76e-3)" "unprognostic (1.85e-3)" "unprognostic (3.67e-2)" "unprognostic (2.36e-3)" "unprognostic (3.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.91e-1)" "unprognostic (3.15e-1)" 118.6 136.8 124.2 62.0 127.4 108.1 100.9 124.3 173.8 77.1 108.4 130.2 52.9 116.2 160.1 73.0 90.2 56.3 134.4 136.9 133.0 103.7 98.4 93.1 44.3 124.5 129.1 87.0 86.5 81.6 84.3 104.9 130.2 83.0 60.5 106.8 72.4 97.0 193.5 66.9 62.6 114.5 121.5 63.6 85.2 47.3 130.2 71.8 98.9 160.8 47.6 117.2 76.8 125.3 335.9 100.3 173.3 165.7 211.5 172.3 131.3 241.7 211.1 198.0 240.4 145.0 354.0 86.4 370.3 215.2 517.4 111.6 126.3 116.8 255.5 91.7 96.9 73.7 113.2 109.5 329.6 137.7 115.2 132.7 183.1 158.1 211.1 207.7 155.2 128.6 231.7 387.1 276.5 216.7 196.0 195.7 285.7 241.5 145.0 94.1 152.6 173.9 233.1 118.4 166.3 208.6 245.4 235.0 283.0 167.7 88.0 169.9 171.0 156.1 65.5 271.9 395.5 145.2 212.2 123.8 376.9 252.7 432.0 39.5 34.1 47.0 24.8 30.5 41.0 23.6 34.2 31.5 26.7 23.9 24.5 30.5 33.9 36.5 34.4 47.0 37.3 39.6 124.2 127.4 124.3 173.8 136.9 133.0 124.5 129.1 130.2 121.5 130.2 125.3 230.5 60.9 45.8 72.5 87.3 398.2 611.3 272.9 114.4 72.8 187.7 179.2 102.0 81.5 169.0 108.5 18.8 207.0 111.9 126.2 416.7 211.7 53.4 107.7 102.6 168.8 98.2 122.9 64.7 213.3 384.1 179.0 40.8 160.8 106.1 95.0 103.9 137.6 233.9 121.1 49.6 76.3 290.9 111.1 384.6 33.2 112.2 174.5 318.4 29.0 114.3 473.6 65.9 30.2 30.6 271.5 109.2 151.6 119.9 620.3 87.8 296.6 85.0 68.7 124.9 149.4 312.2 355.1 173.4 144.7 405.6 421.1 110.4 86.9 79.7 724.9 RHOA "ARH12, ARHA, Rho12, RHOH12" ENSG00000067560 "Ras homolog family member A" P61586 3 49359139-49412998 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Host-virus interaction" Hydrolase "Cancer-related genes, Disease variant, Ectodermal dysplasia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005052 Approved Supported "Plasma membrane,Cytosol" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB005052: AB_562216" "unprognostic (1.50e-1)" "unprognostic (3.38e-1)" "prognostic favorable (3.08e-4)" "unprognostic (8.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.39e-1)" "unprognostic (8.83e-2)" "unprognostic (9.44e-3)" "unprognostic (2.21e-2)" "unprognostic (4.29e-2)" "prognostic favorable (3.21e-6)" "unprognostic (5.14e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (4.52e-2)" 452.4 315.0 234.6 357.9 258.6 473.4 360.0 257.1 274.1 310.4 237.4 351.9 274.6 293.8 298.6 362.6 269.2 267.1 269.6 220.8 271.2 286.9 274.5 430.9 396.3 282.9 245.8 297.2 225.3 269.4 164.3 396.8 287.2 244.5 369.3 113.3 238.0 315.6 331.0 281.3 281.0 416.9 259.3 329.1 292.1 154.1 257.5 387.7 326.3 298.5 454.9 358.2 273.6 292.5 470.4 406.1 500.9 512.7 569.9 858.9 370.8 930.1 735.7 790.3 722.4 347.6 527.4 721.8 251.6 1404.1 448.8 259.5 560.4 630.6 817.6 505.7 323.3 678.8 488.0 416.0 604.2 647.9 472.8 668.2 437.8 643.2 508.1 799.7 1038.0 391.9 361.1 437.9 967.5 254.3 717.3 739.0 441.4 548.2 497.1 325.5 451.4 610.5 701.9 559.6 167.7 387.3 599.0 464.5 495.4 499.4 301.7 819.6 972.1 558.4 483.2 737.2 725.7 388.0 775.6 754.8 567.9 691.6 678.3 716.9 1105.5 1160.5 480.1 1358.8 423.8 432.7 415.6 479.6 806.9 379.3 314.5 397.1 1282.7 440.9 1398.1 645.5 554.9 1884.8 234.6 258.6 257.1 274.1 220.8 271.2 282.9 245.8 287.2 259.3 257.5 292.5 502.8 387.8 265.2 20.5 374.6 270.9 260.0 236.1 251.6 47.1 239.4 223.1 141.1 178.7 220.9 180.3 6.2 355.8 373.1 447.2 340.4 339.5 48.2 174.2 243.7 413.8 234.4 319.3 26.1 347.8 709.8 386.2 313.9 201.0 257.3 141.6 312.7 173.2 760.0 82.4 27.0 344.9 191.2 771.9 495.8 55.6 335.2 683.7 327.3 52.5 710.0 219.9 389.3 24.6 51.4 398.0 354.6 407.7 375.7 334.1 341.3 350.8 201.1 40.8 276.1 354.1 450.1 264.4 253.6 390.8 279.6 525.2 359.5 299.1 347.7 371.4 RNF130 "G1RZFP, GOLIATH, GP" ENSG00000113269 "Ring finger protein 130" Q86XS8 5 179911651-180072113 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 295.7;Kupffer cells: 393.7;Macrophages: 283.0;monocytes: 276.4;Oligodendrocytes: 514.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 261.6;classical monocyte: 513.2;eosinophil: 331.3;intermediate monocyte: 355.0;myeloid DC: 407.4;neutrophil: 890.5;non-classical monocyte: 328.7;plasmacytoid DC: 317.2" "Group enriched" "Detected in all" 11 "dendritic cells: 407.4;granulocytes: 890.5;monocytes: 513.2" "Cell line enhanced" "Detected in many" "HMC-1: 179.3" "Low region specificity" "Detected in all" HPA014499 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA014499: AB_1856328" "unprognostic (2.01e-1)" "prognostic favorable (6.32e-4)" "unprognostic (2.43e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-3)" "unprognostic (2.93e-2)" "unprognostic (1.78e-1)" "unprognostic (4.00e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (8.41e-2)" "unprognostic (4.17e-2)" "unprognostic (4.32e-1)" "unprognostic (1.38e-2)" 94.2 43.4 79.7 47.7 103.2 94.0 50.2 102.3 114.1 55.5 75.5 40.1 28.1 42.1 35.6 26.4 46.8 55.9 36.2 81.4 85.8 49.4 167.1 62.6 39.2 112.8 94.6 52.2 64.2 28.0 16.6 48.4 110.6 35.1 41.9 14.3 84.6 60.2 33.2 14.6 32.6 52.6 98.4 51.8 34.7 17.5 92.3 17.7 32.3 53.7 25.8 51.6 19.3 138.2 32.7 26.8 125.5 110.9 117.4 54.5 21.9 20.9 29.1 24.1 25.3 8.4 31.8 0.1 69.6 47.5 47.7 3.0 81.5 49.7 26.0 0.3 54.6 57.7 11.8 25.4 27.3 14.9 179.3 52.2 25.9 2.3 15.3 65.6 42.3 57.3 9.7 0.4 27.0 71.0 28.7 68.8 32.7 6.7 33.8 65.9 27.9 0.1 38.7 7.4 68.4 28.8 43.2 34.4 126.5 45.7 40.8 38.6 36.6 50.6 18.9 38.8 27.1 0.4 24.1 6.2 7.7 132.0 41.2 261.6 513.2 331.3 25.4 355.0 21.7 15.8 10.9 12.3 407.4 15.8 12.4 13.6 890.5 53.6 328.7 317.2 1.6 323.8 79.7 103.2 102.3 114.1 81.4 85.8 112.8 94.6 110.6 98.4 92.3 138.2 75.0 19.2 21.4 119.1 22.4 14.1 22.6 27.0 12.5 26.9 55.0 45.5 35.1 81.5 34.7 42.3 52.1 11.2 123.7 26.9 23.5 56.8 11.8 49.0 38.8 48.3 16.3 69.2 119.0 76.5 16.6 57.9 25.5 38.3 82.9 28.9 47.5 147.0 295.7 6.7 144.0 36.1 36.7 393.7 170.7 24.2 36.7 283.0 32.0 141.5 276.4 21.8 28.8 242.8 514.2 41.6 32.1 48.2 11.7 27.2 32.6 52.0 56.3 20.3 46.0 32.4 48.5 13.2 32.9 10.9 12.9 8.8 26.2 33.7 52.9 23.3 ROCK1 p160ROCK ENSG00000067900 "Rho associated coiled-coil containing protein kinase 1" Q13464 18 20946906-21111813 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 406.2;Late spermatids: 505.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004562, HPA007567, HPA045639" Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "CAB004562: AB_628223, HPA007567: AB_1856393, HPA045639: AB_2679401" "unprognostic (7.86e-2)" "unprognostic (2.86e-2)" "unprognostic (1.22e-1)" "unprognostic (6.63e-2)" "unprognostic (9.90e-2)" "unprognostic (1.17e-1)" "unprognostic (6.74e-2)" "unprognostic (1.00e-1)" "unprognostic (1.63e-1)" "unprognostic (8.89e-3)" "prognostic unfavorable (9.93e-4)" "unprognostic (3.85e-2)" "unprognostic (8.93e-3)" "unprognostic (3.04e-2)" "unprognostic (5.47e-2)" "unprognostic (3.19e-1)" "unprognostic (1.28e-1)" 8.0 4.2 3.8 5.7 4.8 18.2 6.0 4.4 3.9 5.3 4.6 5.0 3.6 5.9 4.6 4.2 6.3 4.2 5.5 2.8 3.5 4.4 4.8 7.6 5.5 5.4 4.0 5.4 5.1 2.9 2.9 4.4 4.9 4.4 3.2 4.8 4.4 3.4 2.6 3.7 5.2 3.2 4.4 6.2 5.8 2.6 4.5 5.5 4.5 1.9 4.2 6.6 5.4 5.3 6.5 3.9 3.9 3.8 7.2 7.7 6.3 8.9 4.3 3.9 4.2 6.6 2.7 8.0 6.2 10.5 2.1 5.2 3.6 5.2 7.8 11.4 4.1 6.4 7.3 2.9 3.6 17.9 9.6 5.6 4.6 5.8 4.7 3.2 6.0 3.1 3.7 7.9 4.6 4.1 8.5 3.8 3.2 4.3 6.6 11.9 4.5 3.1 3.7 5.9 4.5 3.5 7.1 4.6 3.6 3.4 4.6 6.7 9.9 7.7 6.4 7.1 7.2 10.7 5.3 9.0 5.8 7.5 4.8 3.0 5.0 6.8 5.0 3.2 4.0 3.9 3.6 3.8 4.2 5.0 3.5 3.5 18.0 2.8 4.0 5.5 3.6 2.5 3.8 4.8 4.4 3.9 2.8 3.5 5.4 4.0 4.9 4.4 4.5 5.3 98.2 96.1 88.7 64.6 112.6 46.3 60.4 30.7 43.9 100.4 32.2 35.6 138.6 28.6 61.4 33.1 131.3 57.5 136.9 36.6 15.6 62.5 406.2 64.8 86.9 94.4 99.0 47.9 81.3 38.0 64.9 78.4 62.7 73.8 72.7 68.5 60.0 47.4 60.3 60.6 74.2 45.8 40.7 135.3 126.7 505.0 97.6 166.2 65.8 106.8 137.1 52.3 204.9 87.0 140.0 70.9 62.8 138.8 83.2 63.2 32.3 21.0 44.6 128.6 170.9 81.4 197.6 107.4 80.9 38.7 36.7 43.0 127.4 70.5 38.9 73.3 RPF1 BXDC5 ENSG00000117133 "Ribosome production factor 1 homolog" Q9H9Y2 1 84479259-84498352 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024642 Supported Supported Nucleoli No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoli "HPA024642: AB_1856428" "unprognostic (1.56e-3)" "unprognostic (2.65e-1)" "unprognostic (3.63e-2)" "unprognostic (7.95e-3)" "unprognostic (2.16e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (2.86e-1)" "unprognostic (1.04e-1)" "unprognostic (4.81e-2)" "unprognostic (1.73e-2)" "unprognostic (2.45e-1)" "unprognostic (1.45e-1)" "unprognostic (3.90e-2)" "unprognostic (1.53e-2)" "unprognostic (1.42e-2)" "unprognostic (2.71e-1)" 24.4 21.6 13.7 19.0 17.4 44.9 24.7 14.7 19.4 23.5 15.8 28.1 17.7 26.0 23.0 27.0 23.2 14.1 34.2 13.5 15.4 28.0 26.1 20.5 26.8 13.7 14.0 20.7 22.8 18.8 21.0 14.9 13.8 20.8 20.9 16.8 21.9 15.5 42.7 26.1 23.2 18.1 13.4 26.2 25.6 25.3 13.9 29.4 23.3 23.9 28.1 24.9 23.3 14.8 43.1 29.2 36.6 30.2 27.1 35.5 40.5 46.8 36.5 53.2 47.0 21.4 17.6 31.9 50.1 33.9 89.0 31.7 54.3 43.2 57.7 51.0 57.6 85.2 30.7 37.8 37.2 80.0 25.4 29.0 63.0 56.0 39.2 30.7 42.6 60.7 79.9 40.7 46.9 21.8 76.3 53.0 91.5 43.0 62.5 48.3 58.5 25.7 51.3 47.6 45.2 42.2 27.7 52.7 107.3 32.8 29.6 53.4 30.3 40.1 41.3 64.8 90.4 29.5 39.0 73.0 19.2 71.0 37.0 64.0 35.2 34.6 41.4 41.0 45.4 65.4 46.0 42.0 37.4 58.6 51.3 50.7 14.7 52.6 46.3 39.5 52.9 47.4 13.7 17.4 14.7 19.4 13.5 15.4 13.7 14.0 13.8 13.4 13.9 14.8 28.2 38.5 39.5 7.2 35.8 34.7 41.5 71.6 12.0 15.7 20.4 19.6 39.3 30.0 43.0 16.5 16.7 35.5 51.7 18.0 74.3 60.3 72.7 34.9 27.6 35.0 33.5 17.2 10.1 64.1 33.1 25.0 16.8 26.5 65.2 18.6 28.9 36.6 44.0 8.4 9.8 29.6 28.5 31.7 30.2 13.2 32.6 28.4 28.4 9.4 37.0 30.1 60.8 8.5 10.4 53.0 23.6 35.0 16.2 26.8 21.7 67.4 53.8 25.6 46.0 23.4 43.3 94.7 63.7 18.0 32.7 27.5 40.3 21.4 36.0 39.7 RPL22L1 ENSG00000163584 "Ribosomal protein L22 like 1" Q6P5R6 3 170864875-170870208 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 651.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 912.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048060, HPA056207, HPA068294" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA048060: AB_2732544, HPA056207: AB_2683065, HPA068294: AB_2732781" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.59e-1)" "unprognostic (1.45e-2)" "unprognostic (1.94e-1)" "unprognostic (2.31e-3)" "unprognostic (1.01e-2)" "unprognostic (9.50e-2)" "unprognostic (1.97e-1)" "prognostic favorable (8.60e-5)" "unprognostic (1.17e-3)" "unprognostic (4.52e-2)" "prognostic unfavorable (5.13e-12)" "unprognostic (5.12e-2)" "unprognostic (3.55e-1)" "unprognostic (1.23e-1)" "unprognostic (6.96e-2)" 41.4 32.0 10.4 64.2 12.0 93.6 46.7 10.7 20.6 25.6 9.8 36.1 19.0 24.8 17.8 75.3 32.3 17.2 23.5 10.4 11.6 27.4 47.9 25.9 75.3 11.9 11.5 34.0 47.5 8.3 22.4 17.2 12.1 25.1 33.0 7.7 34.2 15.7 9.9 46.6 32.9 26.5 11.4 67.4 38.6 13.7 11.8 39.8 16.9 6.2 63.2 61.3 38.0 16.4 153.8 169.2 54.4 632.1 156.8 912.4 165.5 152.9 349.5 121.7 78.4 72.8 34.8 472.8 34.5 143.1 379.6 39.3 136.4 390.2 67.7 28.8 24.7 43.2 21.4 166.4 632.4 88.7 60.1 670.6 775.2 38.9 409.7 189.0 418.9 257.7 30.4 29.8 672.0 194.3 650.6 49.7 849.1 58.6 31.0 857.7 19.4 72.7 305.4 337.4 9.2 45.7 15.4 75.6 72.1 29.2 105.6 77.2 196.3 23.3 175.9 47.2 216.8 47.1 36.0 76.2 420.5 53.7 489.4 2.2 9.5 4.3 13.2 12.6 26.9 47.1 19.4 17.9 10.7 34.8 12.9 14.5 2.1 28.8 17.8 51.2 13.1 6.9 10.4 12.0 10.7 20.6 10.4 11.6 11.9 11.5 12.1 11.4 11.8 16.4 153.2 9.6 43.7 4.6 379.6 197.6 240.2 260.8 198.6 13.9 185.1 397.2 18.1 55.8 111.4 20.2 4.2 89.8 241.9 111.5 66.5 160.8 37.6 128.4 279.6 138.5 144.6 266.7 3.3 232.3 297.4 169.0 146.3 116.8 106.5 202.8 103.9 129.5 184.7 8.4 4.5 240.7 93.6 187.4 101.4 36.3 139.4 148.9 78.2 2.8 108.7 54.2 69.0 7.5 10.1 400.8 137.1 89.1 651.0 421.5 99.1 94.1 60.5 21.0 46.0 189.5 472.0 67.2 58.9 511.7 247.8 98.4 173.7 260.4 197.5 356.3 RPS27L ENSG00000185088 "Ribosomal protein S27 like" Q71UM5 15 63125872-63158021 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 2535.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA066851 Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA066851: AB_2685737" "unprognostic (4.62e-2)" "unprognostic (5.81e-2)" "unprognostic (1.38e-1)" "prognostic favorable (9.08e-6)" "unprognostic (1.75e-1)" "unprognostic (7.24e-2)" "unprognostic (1.42e-3)" "unprognostic (2.98e-1)" "unprognostic (6.38e-2)" "unprognostic (1.80e-1)" "unprognostic (2.19e-3)" "unprognostic (2.51e-1)" "unprognostic (1.97e-2)" "unprognostic (5.31e-2)" "unprognostic (1.36e-1)" "unprognostic (1.97e-3)" "unprognostic (5.10e-3)" 142.2 242.4 78.6 71.3 80.6 73.2 127.1 81.5 113.1 124.7 102.5 190.8 157.4 108.4 157.9 70.8 117.9 94.8 181.0 78.1 84.2 194.5 266.0 109.4 83.5 82.9 81.7 95.9 247.4 94.0 88.6 69.3 84.5 156.2 178.0 31.8 164.7 106.7 190.1 75.9 161.4 80.7 86.0 103.2 174.7 38.1 81.4 86.3 106.5 97.7 68.2 149.2 94.1 90.0 140.4 383.0 340.4 92.9 486.4 571.3 341.3 432.1 306.0 93.8 225.3 71.1 190.0 130.8 150.9 415.9 166.0 52.9 116.5 212.9 155.7 97.8 157.5 108.3 329.1 512.7 558.7 86.8 287.0 452.1 279.0 211.2 158.4 701.2 535.2 81.2 101.6 127.7 785.1 194.1 112.4 134.9 101.0 178.0 112.6 86.9 163.1 149.5 266.7 278.8 49.2 74.7 157.6 65.8 326.2 677.8 145.4 199.1 571.1 490.6 463.8 106.7 195.3 142.3 132.3 117.5 518.5 235.6 453.8 263.8 132.5 164.6 99.4 145.2 125.2 132.0 149.9 118.1 122.0 105.2 116.9 119.4 44.3 110.9 198.2 121.3 305.2 166.0 78.6 80.6 81.5 113.1 78.1 84.2 82.9 81.7 84.5 86.0 81.4 90.0 210.9 96.1 198.6 9.4 255.9 255.4 262.6 424.8 230.5 33.4 361.3 429.1 349.0 511.9 424.6 410.1 47.9 300.1 144.9 694.7 903.9 802.7 60.9 202.3 185.3 245.8 285.4 184.5 12.6 782.4 1269.2 269.2 327.8 155.5 302.6 250.8 302.0 994.8 542.1 13.5 15.6 742.3 520.8 372.1 358.1 34.4 314.7 270.3 466.0 17.8 1049.6 184.8 221.4 16.1 18.5 1019.3 745.5 297.5 495.5 324.6 1513.1 2535.3 330.9 75.2 263.0 180.5 742.6 144.7 82.1 183.6 247.6 235.2 224.7 214.3 732.5 215.2 RRP9 "RNU3IP2, U3-55K" ENSG00000114767 "Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein" O43818 3 51933429-51941904 "Predicted intracellular proteins" "rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 66.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038798 Uncertain Supported Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA038798: AB_10672653" "unprognostic (5.57e-2)" "unprognostic (9.47e-2)" "unprognostic (2.29e-1)" "unprognostic (1.33e-2)" "unprognostic (4.18e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.90e-5)" "unprognostic (1.24e-1)" "unprognostic (2.00e-1)" "unprognostic (1.63e-1)" "unprognostic (2.82e-2)" "unprognostic (8.25e-3)" "unprognostic (2.60e-3)" "unprognostic (1.17e-1)" "unprognostic (1.71e-1)" "unprognostic (4.15e-2)" "unprognostic (5.92e-2)" 20.5 20.1 9.8 13.7 10.7 12.4 17.3 9.9 12.1 17.1 8.2 13.2 10.9 16.4 5.3 17.7 15.8 6.8 14.5 10.4 9.8 17.7 16.2 13.9 15.7 10.1 10.0 15.8 14.2 10.4 10.5 9.1 9.5 14.6 7.6 5.6 11.6 9.0 28.9 17.8 12.5 9.1 9.3 14.6 13.1 10.8 10.5 9.2 12.6 13.2 10.5 19.1 15.5 10.6 35.8 50.0 23.5 56.2 33.8 18.8 59.5 38.4 20.9 63.7 40.3 85.5 39.6 102.7 15.9 27.3 86.5 32.3 81.9 59.4 25.5 47.1 35.8 69.5 30.6 77.5 67.9 76.6 55.6 39.0 43.0 80.1 75.3 15.5 24.9 35.8 67.0 25.2 28.5 56.7 65.3 76.2 92.6 54.7 126.9 39.7 26.7 78.6 31.4 52.1 28.9 34.1 34.8 38.5 38.8 20.0 20.1 49.2 24.1 44.3 59.4 111.0 160.8 43.0 75.6 96.2 39.5 94.2 71.4 2.1 9.1 0.5 16.4 13.2 17.5 16.4 14.1 14.5 17.0 13.5 10.9 13.2 0.6 18.8 6.5 18.0 12.5 10.0 9.8 10.7 9.9 12.1 10.4 9.8 10.1 10.0 9.5 9.3 10.5 10.6 9.2 0.0 10.5 3.6 15.2 66.8 27.1 29.7 13.1 12.9 11.2 10.3 4.1 10.0 14.0 5.5 4.2 26.8 14.8 8.3 15.6 24.3 8.1 11.2 12.7 12.7 8.4 7.2 1.9 13.4 40.5 12.6 9.7 9.3 15.2 14.4 5.0 7.0 23.4 16.8 1.3 7.2 22.4 5.3 13.4 6.6 8.7 8.7 21.4 1.0 12.9 10.6 16.5 2.0 1.6 20.0 10.3 9.1 11.6 34.2 6.2 22.2 11.9 10.7 6.6 15.6 36.7 8.0 23.8 15.0 50.4 16.7 12.5 16.4 18.9 14.6 SAP30L "FLJ11526, NS4ATP2" ENSG00000164576 "SAP30 like" Q9HAJ7 5 154445997-154461053 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048665, HPA078308" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "HPA048665: AB_2680486, HPA078308: " "unprognostic (3.79e-3)" "unprognostic (1.44e-2)" "unprognostic (1.25e-1)" "unprognostic (7.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.09e-4)" "unprognostic (1.33e-1)" "unprognostic (1.61e-1)" "unprognostic (1.32e-1)" "unprognostic (4.33e-2)" "prognostic favorable (2.06e-5)" "unprognostic (3.36e-1)" "prognostic favorable (1.71e-4)" "unprognostic (1.62e-2)" "unprognostic (3.34e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.69e-4)" 10.0 8.4 12.2 5.3 13.7 1.6 11.3 13.0 13.2 14.0 10.2 14.9 10.5 13.4 9.0 7.1 12.9 6.7 9.8 11.1 12.9 13.1 8.0 9.3 6.8 13.2 13.4 19.7 6.4 13.8 5.0 7.7 12.7 10.6 8.7 6.1 7.3 12.4 14.1 11.4 11.0 11.6 13.7 8.9 8.9 7.7 13.1 9.9 9.3 15.3 8.3 10.9 10.0 13.8 9.0 7.3 13.3 8.8 28.4 22.5 6.5 9.2 19.9 10.4 11.2 4.9 5.0 9.7 7.2 14.0 12.1 7.1 10.1 7.5 11.6 4.9 9.9 7.9 6.8 3.6 8.5 10.5 5.7 8.2 13.4 4.6 11.3 16.0 8.5 9.1 3.3 6.0 8.8 4.5 9.9 6.7 3.3 8.2 5.0 9.4 13.3 4.8 6.0 4.4 8.0 10.5 7.3 15.6 17.6 12.4 5.6 12.8 12.1 7.2 5.3 9.6 6.6 5.6 8.6 5.0 10.6 8.1 4.2 0.0 0.3 0.3 0.5 0.4 0.6 0.2 0.6 0.6 0.3 0.5 0.6 0.4 0.2 1.4 1.2 0.4 0.6 0.3 12.2 13.7 13.0 13.2 11.1 12.9 13.2 13.4 12.7 13.7 13.1 13.8 25.7 19.2 6.9 7.8 7.1 17.3 8.7 4.2 8.0 4.5 17.0 14.1 19.8 17.2 6.3 3.7 6.2 7.7 15.5 26.5 3.9 4.8 22.4 15.6 18.4 17.6 7.2 11.0 6.6 8.2 12.3 18.1 4.6 9.8 1.3 16.4 15.7 16.3 8.5 10.1 6.5 11.4 0.0 9.7 12.4 18.0 20.5 11.3 10.6 9.4 10.7 21.4 14.4 6.0 12.1 10.6 13.9 18.0 7.8 16.9 32.7 10.5 9.5 5.8 0.0 14.9 16.0 16.1 17.2 5.5 18.2 6.3 8.9 10.5 12.1 13.3 SAR1A "SAR1, Sara, SARA1" ENSG00000079332 "Secretion associated Ras related GTPase 1A" Q9NR31 10 70147289-70170523 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006923, CAB022545, HPA048368" Supported Supported "Endoplasmic reticulum" NA NA 660000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "CAB022545: , HPA006923: AB_1856577, HPA048368: AB_2680373" "unprognostic (3.77e-2)" "unprognostic (7.13e-2)" "unprognostic (3.08e-3)" "unprognostic (3.13e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (7.00e-5)" "prognostic unfavorable (4.04e-4)" "unprognostic (1.60e-2)" "unprognostic (1.00e-1)" "unprognostic (1.02e-2)" "unprognostic (4.06e-2)" "unprognostic (2.06e-1)" "unprognostic (2.38e-3)" "unprognostic (1.76e-1)" "unprognostic (4.80e-2)" "unprognostic (1.10e-2)" "unprognostic (7.13e-2)" 77.1 52.8 41.8 38.4 43.5 163.2 48.1 45.1 45.7 43.1 53.3 39.1 26.6 41.0 47.0 41.4 37.3 35.0 44.8 43.8 48.3 43.3 70.2 51.4 36.7 42.8 44.9 41.0 33.9 44.2 37.9 76.0 44.0 38.9 35.5 42.0 39.9 38.9 51.1 38.5 34.5 49.7 47.3 40.7 37.9 23.5 48.4 33.2 39.8 56.3 38.4 45.8 36.2 52.1 85.8 56.3 75.7 131.9 246.1 143.1 61.1 128.3 154.4 115.6 140.0 169.7 78.2 74.4 67.1 153.7 52.8 96.6 94.5 75.9 111.6 103.9 44.3 54.1 65.8 82.5 112.4 86.7 56.6 155.9 68.4 76.4 133.2 119.0 63.8 55.9 68.7 105.9 110.0 60.0 73.8 72.6 65.2 55.6 141.3 70.8 84.4 42.5 88.7 69.7 42.6 73.8 98.0 134.6 72.2 66.8 65.8 59.7 88.6 63.7 94.3 92.2 91.3 72.3 141.3 114.0 84.9 111.7 48.7 75.5 63.5 74.0 88.0 80.9 94.8 47.7 68.5 85.9 58.5 38.6 65.7 88.7 67.9 103.3 72.9 44.8 53.2 95.9 41.8 43.5 45.1 45.7 43.8 48.3 42.8 44.9 44.0 47.3 48.4 52.1 88.4 128.2 110.2 6.8 53.5 235.7 138.0 120.2 25.0 38.6 99.2 62.4 74.7 57.2 105.3 49.7 33.3 120.6 109.8 51.6 54.8 78.4 3.0 52.3 85.8 85.2 42.7 46.1 21.2 77.3 199.0 127.8 23.9 89.7 53.2 46.3 69.7 114.1 101.0 26.9 22.2 72.1 65.1 51.2 208.9 5.6 54.7 68.1 113.8 21.5 58.4 61.9 75.2 16.1 26.4 78.8 56.2 58.6 97.7 141.4 59.1 95.9 67.1 33.4 78.9 73.7 158.8 64.1 51.8 37.2 248.8 238.9 86.3 45.2 53.2 175.2 SART1 "Ara1, HAF, SNRNP110, Snu66" ENSG00000175467 "Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP" O43290 11 65961728-65980137 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Allergen, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031188, HPA031189, HPA031190" Supported Enhanced "Nuclear speckles,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Golgi apparatus" "HPA031188: AB_10600092, HPA031189: AB_10601854, HPA031190: AB_10602289" "unprognostic (2.93e-2)" "unprognostic (1.13e-2)" "unprognostic (1.09e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-1)" "unprognostic (6.99e-2)" "unprognostic (2.52e-3)" "unprognostic (8.15e-2)" "unprognostic (8.97e-2)" "unprognostic (2.10e-1)" "unprognostic (2.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (4.24e-2)" 24.6 18.3 15.5 18.3 16.8 41.6 23.1 15.4 17.4 29.2 14.7 26.0 15.6 29.1 8.0 22.7 25.6 8.6 23.2 14.9 16.1 20.4 21.8 22.9 20.3 16.6 16.2 29.2 25.8 11.7 21.4 14.0 15.9 21.7 7.7 8.0 22.2 14.4 38.1 32.0 24.3 10.9 14.6 32.7 24.8 23.5 15.7 20.9 23.5 13.0 13.3 26.2 24.6 17.9 50.4 60.8 27.2 36.8 26.1 20.7 40.8 37.5 27.2 43.8 28.6 44.2 34.3 56.9 42.4 33.8 52.9 48.7 34.6 35.6 22.0 45.8 33.5 65.6 43.6 41.4 39.0 57.4 52.7 26.2 26.4 40.8 36.3 17.4 27.6 42.3 42.2 39.8 25.6 92.6 74.0 83.5 45.7 27.3 55.9 80.8 39.0 60.7 18.4 33.7 30.5 43.0 35.6 37.2 45.5 12.6 41.7 47.0 40.6 54.5 53.0 53.9 54.1 59.6 49.4 48.3 45.0 28.8 47.0 1.4 2.8 8.1 4.3 3.5 3.6 3.9 4.8 4.4 3.6 3.5 3.5 3.9 4.1 2.8 2.0 3.2 5.4 1.8 15.5 16.8 15.4 17.4 14.9 16.1 16.6 16.2 15.9 14.6 15.7 17.9 17.5 6.4 9.1 7.8 27.8 22.7 24.0 12.2 17.6 19.2 12.2 9.1 9.4 21.5 11.3 16.5 10.4 34.1 27.2 30.5 5.9 23.7 9.0 14.2 16.3 19.8 12.5 32.8 5.1 29.3 31.9 17.6 21.9 16.8 32.4 21.8 21.0 15.6 29.4 16.8 4.8 26.5 16.2 22.5 23.6 8.7 37.0 22.9 17.8 6.5 35.7 23.8 34.0 7.1 7.8 26.3 20.1 33.1 31.2 20.5 28.3 18.5 17.5 26.0 32.9 27.6 34.9 26.7 29.7 18.3 21.7 45.3 28.4 15.5 27.5 18.2 SCAMP2 ENSG00000140497 "Secretory carrier membrane protein 2" O15127 15 74843730-74873365 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014699, HPA019194" Approved Supported "Golgi apparatus,Vesicles" NA NA 71000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "HPA014699: AB_1856605, HPA019194: AB_1856604" "unprognostic (1.74e-1)" "unprognostic (1.27e-2)" "unprognostic (2.05e-1)" "unprognostic (5.23e-3)" "unprognostic (2.89e-1)" "unprognostic (1.38e-1)" "unprognostic (1.53e-2)" "unprognostic (7.23e-2)" "unprognostic (9.73e-3)" "unprognostic (7.26e-2)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic favorable (1.12e-6)" "unprognostic (3.40e-1)" "unprognostic (1.79e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-2)" 43.1 46.7 27.8 40.3 32.8 51.5 40.7 31.9 31.2 40.5 38.8 76.0 75.7 36.9 36.9 103.4 47.4 35.4 32.4 26.1 29.8 44.9 42.0 49.6 47.9 40.7 30.9 26.5 54.5 85.6 29.4 48.9 36.7 35.5 72.7 4.7 92.7 32.4 34.2 68.3 80.1 33.6 33.6 66.8 64.9 36.2 33.3 33.0 38.3 18.9 53.4 38.1 49.4 35.4 44.7 57.3 24.2 37.6 72.0 37.2 72.0 45.0 56.6 46.9 50.1 83.0 102.6 36.5 57.8 68.1 67.7 157.8 72.3 55.9 19.4 145.8 71.1 92.8 31.2 57.6 54.3 48.0 170.9 48.0 97.6 44.4 32.0 37.0 46.0 42.0 31.3 67.5 33.3 68.1 24.6 55.3 24.1 111.0 36.6 42.6 22.3 126.4 54.0 63.1 24.9 25.0 36.7 64.3 42.4 35.4 88.5 76.3 43.4 40.2 23.9 43.8 53.0 46.1 73.2 37.6 37.8 112.2 30.2 118.3 111.3 90.0 94.1 106.9 76.1 80.8 85.3 95.9 81.8 70.9 69.4 75.8 74.4 83.8 119.3 128.7 105.3 120.8 27.8 32.8 31.9 31.2 26.1 29.8 40.7 30.9 36.7 33.6 33.3 35.4 36.0 73.7 31.7 17.9 49.5 17.5 41.7 40.5 19.4 6.8 28.0 24.8 14.4 24.3 53.1 40.5 2.1 156.9 63.4 116.8 15.6 67.4 132.3 30.8 22.0 36.2 37.3 29.0 7.7 92.8 61.9 37.2 54.0 40.6 79.2 31.3 26.4 27.7 164.7 6.7 6.1 77.5 42.7 78.3 44.5 56.2 32.0 77.0 32.0 21.5 56.9 41.4 63.8 12.1 17.9 96.1 75.5 23.0 73.1 54.0 105.7 48.1 52.6 8.4 26.3 25.6 35.8 47.1 35.3 39.6 22.3 136.4 55.1 40.0 64.2 58.5 SDAD1 FLJ10498 ENSG00000198301 "SDA1 domain containing 1" Q9NVU7 4 75940950-75990962 "Human disease related genes, Predicted intracellular proteins" "Protein transport, Ribosome biogenesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035949 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoli Nucleoplasm "HPA035949: AB_10673225" "unprognostic (8.82e-3)" "unprognostic (3.39e-3)" "unprognostic (7.62e-3)" "unprognostic (1.10e-1)" "unprognostic (2.17e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (5.15e-2)" "unprognostic (1.44e-1)" "unprognostic (1.59e-1)" "unprognostic (2.08e-2)" "unprognostic (3.98e-2)" "prognostic favorable (2.13e-4)" "unprognostic (1.57e-1)" "unprognostic (1.41e-1)" "unprognostic (2.24e-2)" "unprognostic (4.62e-1)" 14.6 13.5 10.5 14.8 10.8 7.2 17.9 8.4 12.3 13.6 8.5 14.3 11.9 17.6 19.0 15.3 12.7 8.7 14.3 10.9 11.0 15.0 15.8 12.6 21.2 9.6 8.9 13.7 17.7 17.7 8.9 12.9 9.3 14.2 15.1 6.8 15.0 16.2 22.9 14.8 11.1 17.1 8.5 15.5 14.0 21.3 11.1 16.4 21.2 16.4 20.2 18.8 11.7 10.2 29.8 11.8 28.5 38.9 33.1 29.8 30.6 41.3 35.9 34.0 29.1 36.6 42.0 46.7 30.2 38.1 32.4 29.7 44.5 40.5 42.3 41.2 23.0 39.9 24.4 30.6 32.7 68.5 43.9 26.4 45.0 36.3 40.4 21.1 30.0 31.2 72.7 37.8 36.4 33.1 69.6 25.1 47.4 48.3 18.1 41.8 53.5 39.3 32.7 32.6 43.3 35.6 28.1 57.0 48.9 31.1 26.4 39.6 29.1 36.6 36.7 44.4 34.8 33.9 37.6 62.0 40.7 31.1 46.0 10.4 14.5 4.1 19.1 19.1 23.8 17.8 23.0 21.1 15.3 20.1 23.0 19.5 2.3 23.4 27.5 13.0 21.5 15.9 10.5 10.8 8.4 12.3 10.9 11.0 9.6 8.9 9.3 8.5 11.1 10.2 36.2 19.2 34.7 15.0 45.7 27.5 26.8 45.1 35.3 21.1 21.3 29.1 12.3 14.3 46.0 22.0 6.2 30.6 35.7 14.5 35.2 37.7 109.0 12.1 29.9 25.2 22.8 35.3 34.0 24.9 32.2 27.4 20.9 18.7 49.4 26.3 18.9 22.1 37.9 13.5 31.8 22.6 36.7 24.3 16.3 106.7 25.4 30.0 24.9 30.9 40.3 23.7 42.2 23.6 29.9 33.4 18.3 33.1 49.0 37.1 17.1 46.6 26.1 20.0 19.7 33.2 38.7 75.6 100.7 47.5 33.1 25.0 38.1 33.2 27.9 22.4 SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716460 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047533 Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear membrane" "Golgi apparatus" "HPA047533: AB_2680078" "unprognostic (8.81e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "prognostic favorable (1.94e-5)" "unprognostic (3.39e-2)" "prognostic unfavorable (5.99e-5)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-2)" "unprognostic (6.17e-2)" "unprognostic (6.24e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "prognostic favorable (2.95e-4)" "unprognostic (7.89e-2)" 142.9 138.1 66.2 83.4 69.4 172.2 136.2 69.0 80.4 147.1 76.6 110.8 82.9 111.0 202.5 81.6 103.6 97.5 98.4 63.7 72.6 137.2 152.3 107.9 112.6 74.1 67.2 168.6 139.4 114.6 84.5 115.1 73.9 82.0 124.9 37.0 95.9 87.5 154.3 70.5 86.4 96.3 72.4 86.2 95.3 61.5 69.4 93.2 177.5 147.4 98.2 137.3 94.0 75.3 201.7 320.7 286.7 425.4 368.5 462.8 225.4 310.1 356.5 241.9 291.2 347.1 443.0 99.0 198.8 370.3 277.2 408.3 409.1 243.4 255.5 267.1 239.4 279.4 358.8 324.9 311.7 213.4 281.2 315.8 305.0 169.1 285.1 366.0 337.9 116.7 295.8 244.3 315.1 363.1 89.2 345.8 282.1 266.2 135.4 101.6 368.4 302.9 472.6 424.4 131.2 300.8 257.3 239.5 598.5 407.0 248.5 416.6 254.3 240.0 181.0 209.8 361.9 224.4 509.6 150.0 226.4 331.7 180.6 83.5 161.1 89.7 95.1 173.7 95.0 101.0 114.8 104.7 165.8 90.0 95.1 98.0 111.6 134.3 184.8 160.9 168.8 200.8 66.2 69.4 69.0 80.4 63.7 72.6 74.1 67.2 73.9 72.4 69.4 75.3 261.1 89.8 99.1 25.8 131.8 107.1 179.4 356.6 90.5 30.0 163.7 202.6 68.2 228.8 188.0 128.8 22.9 309.1 171.9 111.1 238.7 258.8 46.3 118.5 268.0 217.2 157.4 101.7 21.2 247.3 655.3 206.0 120.8 184.1 218.4 191.0 197.7 165.5 363.3 20.2 22.8 218.7 168.9 386.7 337.2 100.6 299.5 337.3 158.3 24.4 396.7 110.5 204.9 26.7 38.3 183.4 136.3 166.3 197.9 185.7 142.7 350.9 99.3 38.2 170.9 173.5 225.5 233.5 169.6 135.2 119.9 305.8 153.4 237.6 210.7 242.2 SERBP1 "CGI-55, CHD3IP, DKFZP564M2423, HABP4L, PAI-RBP1, PAIRBP1" ENSG00000142864 "SERPINE1 mRNA binding protein 1" Q8NC51 1 67407810-67430415 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020559, CAB026297" Supported Enhanced Cytosol NA NA 810000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB026297: AB_425924, HPA020559: AB_1856701" "unprognostic (1.58e-1)" "unprognostic (6.35e-2)" "unprognostic (1.45e-2)" "unprognostic (6.80e-3)" "unprognostic (2.71e-3)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.36e-4)" "unprognostic (1.98e-2)" "unprognostic (1.32e-3)" "unprognostic (5.97e-2)" "unprognostic (8.25e-3)" "unprognostic (3.04e-1)" "unprognostic (1.33e-2)" "unprognostic (1.40e-2)" "unprognostic (4.76e-1)" "unprognostic (6.64e-2)" "unprognostic (1.34e-3)" 116.2 79.6 45.9 110.1 48.9 130.5 106.9 45.7 48.5 98.3 44.4 91.2 99.6 89.9 65.7 188.2 81.5 66.5 93.4 42.5 46.5 85.9 131.4 76.6 123.8 51.6 47.5 86.8 121.1 131.5 48.0 92.9 52.4 77.3 84.5 47.6 119.0 66.2 336.9 149.6 92.7 82.1 50.3 81.4 94.1 82.9 49.3 125.7 91.1 159.0 118.1 101.4 118.4 52.8 444.4 272.4 274.9 280.4 236.9 214.0 420.9 452.9 163.8 294.7 241.6 524.8 195.4 828.9 341.1 236.0 294.6 337.4 435.2 411.2 309.5 375.7 535.8 764.1 488.7 460.7 207.0 614.9 290.8 221.3 272.1 384.6 356.0 205.9 319.7 276.0 867.4 293.0 236.2 314.9 494.9 412.9 978.1 298.1 355.2 566.3 600.4 429.8 231.0 349.8 468.8 330.8 351.0 385.6 442.4 231.1 212.0 386.4 345.9 283.4 351.5 421.2 618.3 273.6 369.2 747.9 233.0 603.3 326.9 37.8 84.1 53.7 100.4 92.5 125.4 101.3 99.0 100.9 107.5 102.1 114.6 105.6 27.1 147.4 90.1 98.2 131.5 119.2 45.9 48.9 45.7 48.5 42.5 46.5 51.6 47.5 52.4 50.3 49.3 52.8 251.3 250.0 225.5 17.6 262.6 686.4 437.3 363.8 536.7 146.7 262.1 251.8 144.8 214.4 311.4 117.7 91.8 271.5 343.7 200.0 242.6 324.4 555.9 368.1 411.9 314.9 230.1 398.8 24.1 361.5 531.0 231.0 169.7 400.5 219.2 215.6 179.2 331.5 297.9 143.0 24.6 338.7 183.1 247.7 281.2 240.9 221.2 214.2 192.1 27.2 298.4 153.6 325.4 26.7 33.2 349.3 192.0 278.7 277.4 540.5 168.4 323.0 206.3 139.7 138.1 301.6 516.0 569.8 281.6 597.9 719.7 229.3 271.4 318.8 405.0 470.2 SERF2 "4F5REL, FAM2C, H4F5rel, HsT17089" ENSG00000140264 "Small EDRK-rich factor 2" P84101 15 43777087-43804427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056613 Uncertain Nucleoplasm,Nucleoli NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA056613: " "unprognostic (3.29e-1)" "unprognostic (7.29e-2)" "unprognostic (1.13e-3)" "prognostic favorable (5.33e-4)" "unprognostic (1.40e-1)" "unprognostic (3.91e-2)" "unprognostic (6.06e-2)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (2.50e-1)" "unprognostic (3.04e-1)" "unprognostic (1.36e-1)" "unprognostic (3.37e-2)" "unprognostic (2.84e-1)" "unprognostic (3.35e-2)" "unprognostic (2.76e-2)" "unprognostic (9.42e-2)" 760.6 1067.4 704.4 446.7 726.4 944.9 619.4 750.2 906.3 650.8 1027.1 728.4 443.4 509.9 776.2 887.9 456.8 469.4 1187.9 698.1 712.2 1002.2 1328.7 700.8 686.4 737.1 725.3 474.3 795.1 490.9 569.3 484.2 734.7 794.5 631.9 72.8 823.7 312.8 636.9 631.1 593.2 507.4 739.4 745.3 784.3 400.2 759.4 450.7 706.6 723.6 628.9 595.0 634.1 758.8 497.5 770.8 573.8 792.9 1963.2 1431.3 438.9 844.8 1042.5 540.4 682.7 991.5 470.0 250.4 694.7 1429.2 698.7 641.1 454.6 623.8 271.1 699.6 526.2 610.9 1074.9 1936.8 934.7 581.8 1235.8 1349.9 810.5 425.8 452.1 836.1 783.5 680.7 630.2 1593.5 1067.4 1441.8 758.6 1337.2 501.5 1849.7 885.1 743.9 382.6 1147.2 1462.5 1695.7 450.6 481.1 458.9 1871.5 463.9 488.4 1574.7 2363.9 682.9 920.0 469.0 1409.4 669.3 593.3 886.2 1837.8 989.2 1032.8 980.4 4033.8 5391.9 5884.9 2716.6 5055.2 2481.3 3853.8 2938.5 2784.5 4649.4 3901.8 2713.3 2731.7 3154.6 2568.8 4495.9 6486.5 3793.5 12856.7 704.4 726.4 750.2 906.3 698.1 712.2 737.1 725.3 734.7 739.4 759.4 758.8 1269.2 506.4 789.0 0.0 1149.8 1151.3 1379.1 3393.0 861.6 53.9 2373.1 2483.2 2229.8 1338.2 2099.5 1736.1 54.2 2660.9 1475.6 2388.2 3897.3 1707.6 576.8 1243.6 1343.1 1283.3 1167.5 1310.8 0.5 2255.2 3410.2 1489.3 1403.7 1261.0 785.9 775.2 1532.4 2884.5 3545.2 47.1 0.5 2862.6 2278.6 2262.1 2298.5 319.2 1225.3 2102.8 1817.8 0.0 2626.4 544.5 1881.6 1.5 0.3 1804.7 2363.9 992.2 1546.7 2188.9 3013.2 5083.6 1950.6 148.4 604.8 680.1 1737.3 750.2 381.1 1725.5 1556.5 3275.8 1216.9 1446.6 2042.5 2819.5 SF3A3 "PRP9, PRPF9, SAP61, SF3a60" ENSG00000183431 "Splicing factor 3a subunit 3" Q12874 1 37956975-37990075 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032054, HPA032055" Supported Supported "Nucleoplasm,Nuclear speckles" NA NA 57000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" Nucleoplasm "HPA032054: AB_10602184, HPA032055: AB_2674130" "unprognostic (1.56e-1)" "unprognostic (1.21e-1)" "unprognostic (7.08e-3)" "unprognostic (6.19e-3)" "unprognostic (1.06e-1)" "unprognostic (5.68e-2)" "prognostic unfavorable (2.11e-8)" "unprognostic (1.34e-1)" "unprognostic (2.74e-2)" "unprognostic (5.74e-3)" "unprognostic (9.18e-2)" "unprognostic (4.79e-1)" "unprognostic (1.23e-2)" "unprognostic (2.52e-3)" "unprognostic (8.39e-2)" "unprognostic (2.24e-1)" "unprognostic (3.68e-2)" 24.6 23.4 22.3 29.2 22.6 57.9 31.7 24.1 29.0 25.6 23.2 25.1 20.4 30.5 33.7 23.3 27.5 19.1 18.6 22.0 22.8 26.0 27.4 22.9 39.0 22.6 22.6 32.1 20.3 30.6 16.2 25.4 22.9 24.9 30.0 29.9 23.5 28.8 49.6 29.2 21.4 31.7 22.3 27.4 20.0 27.5 23.4 43.4 26.9 27.4 44.6 28.1 18.8 24.0 84.4 57.0 108.1 90.8 63.3 57.7 129.6 82.2 69.1 131.9 106.4 97.2 84.4 165.8 68.1 73.6 51.6 71.5 136.7 108.6 162.3 74.9 125.7 206.3 92.3 86.7 57.9 261.1 93.5 54.9 75.4 135.5 88.4 58.6 89.9 112.6 176.1 60.0 95.2 53.2 131.4 123.0 268.0 80.4 89.9 156.8 197.0 110.7 59.4 83.5 95.8 69.4 104.2 47.1 83.9 95.1 54.0 90.3 82.0 70.3 79.6 64.9 157.2 57.6 89.5 166.4 65.6 215.6 92.1 37.2 41.3 28.4 56.1 53.3 55.0 54.9 65.3 56.7 53.1 68.9 69.4 58.9 4.6 56.2 61.8 32.5 75.5 61.7 22.3 22.6 24.1 29.0 22.0 22.8 22.6 22.6 22.9 22.3 23.4 24.0 37.3 51.3 35.0 11.4 42.2 47.3 38.6 46.6 55.2 37.0 21.3 27.7 22.7 20.0 42.3 22.0 22.9 59.1 40.7 12.1 39.2 44.4 37.9 23.7 42.4 35.8 15.6 53.6 15.7 38.1 69.2 41.6 15.3 25.3 42.4 43.0 25.0 23.6 51.5 26.9 14.9 23.9 34.6 28.0 39.8 14.0 39.7 34.2 39.2 6.5 82.9 45.6 44.3 11.1 11.5 35.4 13.1 54.2 41.5 28.5 19.0 29.2 27.8 38.6 39.5 47.2 68.3 120.8 55.2 36.5 41.8 33.0 42.9 53.5 31.4 24.0 SF3B1 "Hsh155, Prp10, PRPF10, SAP155, SF3b155" ENSG00000115524 "Splicing factor 3b subunit 1" O75533 2 197388515-197435079 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050275 Approved Enhanced "Nuclear speckles" NA NA 94000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA050275: AB_2681071" "unprognostic (6.86e-2)" "unprognostic (2.78e-1)" "unprognostic (2.14e-1)" "unprognostic (3.51e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-3)" "unprognostic (2.44e-3)" "unprognostic (3.31e-3)" "unprognostic (1.25e-2)" "unprognostic (2.20e-1)" "unprognostic (6.79e-2)" "unprognostic (1.78e-2)" "unprognostic (2.57e-2)" "unprognostic (9.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" 183.8 173.9 101.7 132.7 112.4 304.8 180.7 120.5 126.1 222.8 136.8 170.9 110.4 195.8 200.0 136.8 183.8 123.2 135.7 98.2 100.8 135.4 168.5 162.8 203.0 105.7 101.9 226.5 200.7 154.9 147.8 165.3 111.0 163.2 147.3 138.4 180.4 133.2 172.4 156.5 231.6 116.5 107.5 287.8 169.2 91.4 104.9 221.9 167.8 144.8 199.3 154.4 167.1 135.8 134.9 105.4 288.6 155.9 222.8 219.2 237.8 172.6 196.7 163.2 205.9 233.0 147.2 247.5 116.6 193.1 165.8 133.7 273.4 151.2 271.8 196.5 154.8 237.5 257.4 294.3 155.4 270.1 198.6 232.1 163.0 175.9 209.3 278.6 205.9 171.0 210.2 174.0 192.3 134.2 251.1 285.6 231.4 167.5 163.8 234.4 197.9 182.9 245.8 286.4 154.2 186.7 174.7 118.2 139.2 345.1 115.2 242.5 186.8 126.9 109.4 123.3 145.8 168.7 238.8 342.0 123.7 174.8 146.5 49.8 50.4 57.5 54.5 51.7 55.4 46.1 46.2 50.9 60.5 44.1 48.7 49.2 60.8 56.7 52.5 37.5 71.3 56.2 101.7 112.4 120.5 126.1 98.2 100.8 105.7 101.9 111.0 107.5 104.9 135.8 175.6 179.5 222.9 92.4 187.4 119.0 172.0 127.1 125.7 103.4 96.4 83.3 129.2 72.9 194.0 92.0 73.0 116.8 224.1 90.1 56.7 104.8 9.2 123.9 191.0 143.1 110.5 109.0 55.5 94.8 102.3 151.6 132.0 179.0 246.9 171.1 107.1 74.4 100.6 94.2 59.7 108.1 89.5 124.7 144.1 20.6 120.2 166.1 76.5 75.9 163.9 111.1 116.4 87.0 121.1 112.0 68.3 104.6 195.6 103.8 84.2 70.5 221.5 98.5 118.3 159.5 227.9 104.6 100.5 94.3 118.8 142.7 216.2 119.4 91.4 156.1 SF3B4 "Hsh49, SAP49, SF3b49" ENSG00000143368 "Splicing factor 3b subunit 4" Q15427 1 149923317-149927803 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028578, HPA064660" Approved Approved "Nuclear speckles" NA NA 36000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA028578: AB_10601601, HPA064660: AB_2685314" "unprognostic (2.43e-1)" "unprognostic (6.58e-2)" "unprognostic (2.49e-2)" "unprognostic (9.26e-3)" "unprognostic (2.74e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (3.11e-1)" "unprognostic (2.04e-1)" "unprognostic (6.60e-2)" "unprognostic (2.12e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.74e-7)" "unprognostic (9.63e-2)" "unprognostic (6.54e-2)" "unprognostic (3.15e-2)" "unprognostic (1.91e-1)" 35.6 36.8 27.9 42.3 28.4 74.3 31.6 30.1 35.8 36.0 29.3 55.8 39.6 48.5 37.5 45.1 51.8 33.8 28.9 28.6 30.4 29.9 27.1 36.8 48.5 31.1 28.3 47.5 34.6 53.4 26.0 40.1 28.7 32.3 44.2 20.8 40.1 47.9 22.5 62.4 40.1 46.7 28.0 39.4 32.4 46.4 29.1 58.0 39.1 26.9 57.6 50.3 33.4 29.8 153.0 144.1 119.4 110.9 75.5 58.4 172.0 119.0 118.2 188.0 143.0 152.0 125.6 144.2 87.1 139.7 103.0 154.3 150.9 158.2 161.8 95.3 110.7 130.0 77.3 112.8 121.7 156.6 163.5 74.7 122.6 184.0 84.5 59.0 94.6 126.7 116.6 119.6 172.9 456.6 203.9 148.9 199.4 175.9 146.1 157.9 106.4 157.6 137.4 128.2 79.6 147.6 109.8 151.1 92.5 141.4 229.9 205.1 78.3 154.9 170.0 122.9 222.8 169.0 259.4 161.2 124.2 133.8 147.5 70.5 81.1 130.5 84.0 109.8 87.4 80.2 79.6 90.4 71.3 73.1 74.3 71.9 111.2 104.7 120.0 84.6 100.1 67.5 27.9 28.4 30.1 35.8 28.6 30.4 31.1 28.3 28.7 28.0 29.1 29.8 30.4 16.0 13.4 4.2 39.9 54.2 47.5 83.2 65.4 20.0 34.3 41.4 3.9 21.5 41.2 23.9 4.2 80.8 54.2 42.2 60.7 64.3 80.3 38.9 30.4 30.6 26.0 34.3 4.1 51.6 77.5 31.8 27.0 44.5 39.3 32.9 16.8 14.7 53.0 8.4 4.8 40.0 59.0 24.7 42.5 13.3 45.1 34.9 24.9 3.7 61.8 27.5 44.3 4.5 7.0 62.3 35.9 29.3 38.6 32.2 28.5 43.0 49.8 15.9 46.0 30.8 64.6 64.0 51.5 47.0 51.3 94.7 44.9 27.9 36.7 43.8 SMARCC1 "BAF155, CRACC1, Rsc8, SRG3" ENSG00000173473 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1" Q92922 3 47585269-47782106 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011576, CAB016336, HPA024352, HPA026853" Supported Enhanced Nucleoplasm NA NA 31000 "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB011576: AB_2191988, CAB016336: AB_671095, HPA024352: AB_1857274, HPA026853: AB_10603030" "unprognostic (3.47e-1)" "unprognostic (1.65e-1)" "prognostic favorable (3.34e-4)" "unprognostic (2.54e-1)" "unprognostic (1.83e-2)" "unprognostic (3.70e-2)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.33e-2)" "unprognostic (4.28e-3)" "unprognostic (6.92e-2)" "unprognostic (5.53e-2)" "unprognostic (2.78e-2)" "unprognostic (1.66e-2)" "unprognostic (7.99e-2)" "unprognostic (3.84e-1)" "unprognostic (2.31e-2)" "unprognostic (2.45e-1)" 12.2 8.1 19.6 18.6 21.1 21.2 23.5 16.2 19.6 19.3 17.0 23.0 14.7 18.3 15.6 20.1 13.1 11.8 9.4 15.9 17.7 20.0 13.8 13.1 22.2 18.3 19.8 17.8 19.5 14.3 8.3 22.2 18.8 22.4 21.9 9.6 17.0 17.1 19.0 24.1 16.9 16.3 19.7 16.3 16.9 16.7 18.9 34.8 17.7 10.3 30.3 21.0 15.9 20.9 45.1 23.4 95.7 74.9 21.0 35.7 64.3 35.1 32.7 44.5 45.1 42.3 46.6 104.3 27.7 44.4 25.8 37.7 91.2 54.3 64.6 50.3 54.1 102.4 38.4 57.7 31.4 94.8 45.3 30.1 47.0 50.1 55.2 33.1 52.8 68.7 87.5 34.4 48.4 33.4 124.4 48.9 126.8 43.2 35.4 55.1 55.5 92.0 47.2 58.0 42.6 85.5 54.5 52.7 38.9 66.5 45.8 87.1 42.7 29.6 41.7 33.9 58.0 41.9 57.1 122.0 21.6 88.1 42.5 1.9 1.6 1.7 2.7 2.6 2.4 3.9 3.0 3.7 2.1 2.6 2.8 3.3 1.9 2.0 1.9 2.2 3.1 1.9 19.6 21.1 16.2 19.6 15.9 17.7 18.3 19.8 18.8 19.7 18.9 20.9 30.4 41.7 45.9 56.5 61.7 53.0 60.5 37.4 71.7 29.3 60.3 45.5 31.5 34.3 58.9 57.0 37.5 79.7 43.7 30.1 13.7 67.9 88.9 60.2 72.3 38.3 91.6 76.9 47.3 46.7 113.0 32.7 49.5 115.7 24.6 103.8 22.1 37.8 30.2 20.2 52.2 64.5 34.6 32.3 36.9 113.1 25.4 41.6 23.2 42.2 57.7 18.9 52.5 98.0 104.9 58.8 29.0 28.6 65.3 83.7 24.1 38.0 34.0 33.0 39.5 44.7 60.1 59.4 108.3 86.0 66.8 72.5 52.4 77.6 61.8 62.4 SMARCD1 "BAF60A, CRACD1, Rsc6p" ENSG00000066117 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1" Q96GM5 12 50085200-50100707 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Chromatin regulator" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004101 Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Vesicles "HPA004101: AB_1080026" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-2)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "prognostic unfavorable (2.53e-8)" "unprognostic (3.62e-2)" "unprognostic (1.44e-1)" "unprognostic (4.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.10e-2)" "unprognostic (1.20e-3)" "unprognostic (2.18e-1)" "unprognostic (3.45e-1)" "unprognostic (1.38e-1)" "unprognostic (5.04e-2)" 25.8 28.1 25.2 23.2 27.6 44.0 24.9 24.4 27.0 23.5 20.8 22.0 23.2 27.9 27.1 27.5 23.8 17.9 18.3 26.3 23.8 25.3 19.0 23.9 35.0 25.7 25.7 26.4 22.5 47.3 19.7 28.9 25.3 23.2 27.2 25.1 24.3 21.8 16.9 24.3 27.8 28.8 24.8 31.3 20.5 23.8 25.8 57.2 26.8 16.1 47.6 23.5 21.7 27.6 28.4 47.6 134.8 75.8 41.1 38.9 68.1 35.1 62.0 100.3 58.2 130.0 42.1 109.4 51.0 67.2 44.4 35.4 112.9 91.5 87.3 84.4 87.0 107.2 49.4 75.8 49.3 95.0 41.1 40.2 60.2 59.8 107.4 66.1 119.5 114.0 93.1 64.8 50.6 67.7 137.6 54.0 166.0 43.2 76.6 165.5 34.9 96.0 57.3 66.1 71.4 121.3 73.1 35.2 139.3 100.4 79.4 78.7 70.4 50.1 56.0 31.7 69.9 91.6 88.2 95.4 40.6 37.7 56.9 3.4 1.2 2.2 2.9 1.2 2.9 3.6 1.6 2.0 1.8 2.7 1.0 3.3 0.5 1.7 1.9 3.5 2.7 1.2 25.2 27.6 24.4 27.0 26.3 23.8 25.7 25.7 25.3 24.8 25.8 27.6 29.7 0.0 9.6 11.1 42.9 16.6 22.3 17.7 42.7 33.7 33.2 30.2 6.5 15.7 20.5 27.6 20.9 21.1 39.6 21.6 52.8 32.8 4.3 20.0 36.9 30.1 31.1 25.7 9.3 29.0 19.4 17.8 14.8 30.5 16.5 40.0 17.5 15.1 17.3 26.9 10.5 18.2 10.2 14.4 13.1 9.1 16.4 16.8 17.8 7.5 27.1 26.5 29.9 11.1 17.1 36.8 14.8 16.1 28.9 28.8 19.5 47.9 9.4 28.8 32.9 31.6 28.2 28.4 36.5 31.3 19.6 11.1 30.0 26.8 19.1 15.9 SMC1A "DXS423E, KIAA0178, SB1.8, SMC1L1, Smcb" ENSG00000072501 "Structural maintenance of chromosomes 1A" Q14683 X 53374149-53422728 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005499, CAB025404" Supported Enhanced Nucleoplasm NA NA 33000 "Cluster 27: Non-specific - Gene expression" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB025404: , HPA005499: AB_1080028" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (4.00e-2)" "unprognostic (5.76e-2)" "unprognostic (1.04e-1)" "unprognostic (9.89e-2)" "unprognostic (1.29e-3)" "unprognostic (1.89e-1)" "unprognostic (9.80e-3)" "unprognostic (9.49e-2)" "unprognostic (4.48e-2)" "unprognostic (6.55e-2)" "unprognostic (2.58e-1)" "unprognostic (4.18e-3)" "unprognostic (6.28e-2)" "unprognostic (2.89e-1)" "unprognostic (9.39e-2)" 16.6 11.8 8.7 28.4 11.7 30.3 17.2 15.0 9.5 13.8 9.6 20.0 18.6 21.0 8.0 17.1 16.7 11.5 15.6 7.8 9.5 16.3 18.8 16.0 34.4 10.2 10.7 19.1 14.4 25.8 6.3 18.2 10.7 14.0 18.4 21.0 15.1 13.0 17.9 18.1 15.9 22.9 8.7 20.1 15.7 7.8 11.3 58.1 16.8 18.8 29.9 15.5 12.4 13.9 110.0 115.1 92.4 76.1 32.4 35.4 51.5 68.0 37.0 76.4 59.4 71.6 60.5 115.8 54.1 40.7 105.2 78.9 162.9 92.6 85.1 91.7 176.0 94.3 133.9 51.1 15.4 134.9 120.9 20.6 23.3 86.0 52.8 19.4 67.5 68.7 144.7 64.7 58.6 69.2 122.0 40.8 139.9 47.8 55.6 117.2 165.5 100.1 34.4 69.4 92.8 83.5 176.9 84.4 33.5 122.8 87.9 54.0 45.7 63.3 68.0 65.1 62.2 45.8 77.9 91.9 39.1 152.1 64.1 2.7 6.8 4.5 7.3 8.5 7.6 5.4 5.8 6.7 8.4 5.8 5.2 6.3 2.7 4.6 12.4 4.6 5.7 6.7 8.7 11.7 15.0 9.5 7.8 9.5 10.2 10.7 10.7 8.7 11.3 13.9 40.7 44.8 39.9 16.0 45.6 24.1 37.0 27.7 28.5 46.6 30.7 27.4 63.5 27.1 47.4 20.2 27.1 43.2 57.7 49.6 7.9 31.6 10.5 46.5 62.6 41.7 19.9 70.7 12.0 27.1 61.4 37.2 29.0 44.0 35.4 42.7 18.9 54.1 47.6 60.6 14.2 43.5 22.4 41.1 27.6 7.6 37.9 51.5 23.2 24.4 55.2 38.1 59.8 16.6 30.2 33.1 23.6 36.1 61.2 40.7 29.0 24.6 47.1 48.4 39.5 49.5 71.0 54.5 51.2 39.8 24.4 48.4 47.9 34.0 51.4 32.0 SMC6 "FLJ22116, SMC6L1" ENSG00000163029 "Structural maintenance of chromosomes 6" Q96SB8 2 17663812-17800242 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 153.4;Spermatocytes: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035057, CAB037186, HPA042733" Uncertain Supported Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB037186: AB_1080031, HPA035057: AB_2674435, HPA042733: AB_2678134" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" "unprognostic (1.50e-2)" "unprognostic (1.33e-3)" "unprognostic (1.70e-2)" "unprognostic (6.57e-2)" "unprognostic (1.38e-2)" "unprognostic (3.91e-2)" "unprognostic (2.03e-2)" "unprognostic (2.94e-3)" "unprognostic (9.33e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.15e-4)" "unprognostic (7.02e-2)" "unprognostic (1.57e-1)" "unprognostic (1.25e-1)" "unprognostic (5.25e-2)" 8.4 5.2 6.8 14.7 7.6 13.3 8.5 11.4 7.7 9.5 31.9 11.9 9.0 9.4 17.4 13.2 8.7 9.4 8.6 8.0 8.4 8.9 17.2 9.0 21.6 6.2 6.9 6.9 6.1 6.0 11.6 14.2 7.4 6.7 13.3 6.8 12.4 10.8 9.4 14.7 11.4 8.7 5.3 14.9 9.8 35.2 8.4 14.3 7.7 8.8 22.6 8.6 11.4 10.6 50.6 24.8 31.9 26.6 33.6 32.2 32.2 26.4 18.6 16.7 16.2 27.9 19.4 43.9 16.6 24.2 27.9 34.4 38.5 31.0 25.7 52.3 25.2 60.3 16.2 42.1 31.3 42.3 31.2 24.3 21.4 27.0 35.1 20.5 38.9 26.4 67.5 35.4 31.9 20.8 32.8 21.7 43.3 25.3 19.7 38.7 90.0 29.9 16.2 27.7 28.0 29.9 38.4 20.0 30.0 35.1 12.7 18.7 42.7 41.3 16.5 32.5 47.2 25.0 43.5 87.9 21.0 45.7 30.0 2.2 3.8 8.2 7.8 4.2 6.6 24.8 6.0 7.1 5.1 26.4 4.3 6.0 3.1 7.5 6.7 27.7 14.4 4.1 6.8 7.6 11.4 7.7 8.0 8.4 6.2 6.9 7.4 5.3 8.4 10.6 25.6 48.1 12.5 34.9 63.7 18.2 21.6 41.5 68.3 15.2 8.4 9.3 36.5 14.3 30.8 5.5 12.5 15.2 51.5 18.9 11.7 17.0 153.4 33.0 26.3 21.9 11.3 36.6 51.1 11.7 27.5 21.0 32.1 18.2 20.8 38.6 15.7 19.3 17.6 6.7 47.9 15.7 16.2 10.0 9.1 123.7 22.4 20.1 26.6 30.0 22.0 12.5 25.7 56.3 60.5 19.7 17.2 27.4 25.3 25.1 16.0 14.5 27.2 17.4 46.0 41.2 67.8 150.0 87.9 37.4 14.2 12.4 22.2 28.9 21.2 14.9 SMIM35 TMPRSS4-AS1 ENSG00000255274 "Small integral membrane protein 35" A0A1B0GVV1 11 118003634-118088299 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.2;kidney: 1.1" "Cell type enhanced" "Detected in single" "Collecting duct cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Karpas-707: 10.9;RPMI-8226: 7.2" "Group enriched" "Detected in some" 5 "basal ganglia: 1.2;olfactory bulb: 3.5" "Region enriched" "Detected in some" 6 "basal ganglia: 7.9" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (8.83e-2)" "unprognostic (3.42e-2)" "unprognostic (2.64e-1)" "unprognostic (1.58e-1)" "unprognostic (3.04e-4)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.64e-1)" "unprognostic (1.88e-1)" 0.1 0.1 0.2 0.5 0.3 1.2 0.2 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.2 1.1 0.1 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.1 0.0 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 7.2 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.2 0.3 0.2 0.1 0.0 0.1 0.0 0.4 0.2 0.2 1.6 0.1 0.2 0.3 0.1 0.5 0.2 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMNDC1 "SMNR, SPF30, TDRD16C" ENSG00000119953 "Survival motor neuron domain containing 1" O75940 10 110290730-110304938 "Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061214, HPA070666" Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nuclear bodies" "HPA061214: AB_2684451, HPA070666: " "unprognostic (4.65e-2)" "unprognostic (1.68e-2)" "unprognostic (2.64e-1)" "unprognostic (3.07e-2)" "unprognostic (3.63e-3)" "unprognostic (5.03e-3)" "prognostic unfavorable (8.08e-6)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (7.20e-4)" "unprognostic (2.68e-3)" "unprognostic (6.88e-3)" "unprognostic (1.35e-1)" "unprognostic (2.82e-1)" "unprognostic (1.80e-1)" "unprognostic (2.00e-1)" 16.3 12.0 7.0 15.1 7.5 31.8 13.7 10.8 11.1 13.8 7.7 13.4 9.9 14.4 8.7 16.2 13.3 11.6 12.4 6.5 7.2 13.6 14.9 14.2 16.9 7.1 6.9 13.5 10.2 13.1 8.9 18.4 7.0 10.0 11.1 16.6 11.5 10.2 24.8 13.2 11.5 14.6 7.5 14.7 11.5 13.1 7.1 20.4 12.1 17.9 18.3 17.3 13.7 9.4 36.2 27.0 38.9 44.9 29.6 35.1 28.9 41.0 42.6 53.3 54.6 35.1 43.7 51.2 25.7 25.9 30.5 38.5 57.8 28.2 59.9 29.0 30.6 51.1 21.9 41.2 35.3 56.9 47.2 27.4 29.7 42.2 71.1 39.5 30.0 29.0 46.8 46.5 41.9 17.1 61.0 55.0 43.5 27.8 18.4 52.0 77.9 26.8 30.0 25.7 19.4 26.0 26.6 22.4 48.9 33.3 27.7 32.3 33.0 31.2 35.2 28.9 52.9 37.8 42.4 76.7 31.4 77.9 24.6 5.7 8.9 14.5 5.2 9.2 6.4 5.4 6.8 6.7 8.6 4.8 5.9 5.9 16.6 6.3 9.8 5.2 8.1 4.3 7.0 7.5 10.8 11.1 6.5 7.2 7.1 6.9 7.0 7.5 7.1 9.4 57.7 28.9 37.1 6.8 53.4 69.6 42.5 27.2 89.4 27.3 31.7 26.7 23.4 14.3 27.9 11.0 20.9 33.0 55.7 23.9 33.2 22.8 10.7 34.2 52.0 41.5 18.6 37.0 7.8 18.0 32.0 39.1 37.8 58.8 58.3 27.3 27.1 26.5 32.4 33.7 8.0 21.4 38.7 40.9 79.7 4.4 29.2 47.7 35.6 6.5 45.8 23.0 22.6 5.0 11.2 21.7 21.0 22.2 45.7 53.3 20.6 40.9 28.6 33.0 19.7 30.8 39.7 46.2 37.7 72.4 83.4 46.1 57.4 33.5 24.1 65.8 SMU1 "BWD, FLJ10805, fSAP57, SMU-1" ENSG00000122692 "SMU1 DNA replication regulator and spliceosomal factor" Q2TAY7 9 33041765-33076674 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019708 Supported Approved Vesicles NA NA 25000 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA019708: AB_1857300" "unprognostic (2.20e-2)" "prognostic favorable (2.66e-4)" "unprognostic (1.17e-1)" "unprognostic (1.58e-1)" "unprognostic (1.80e-2)" "unprognostic (8.44e-2)" "unprognostic (2.59e-3)" "unprognostic (5.06e-2)" "unprognostic (3.04e-2)" "prognostic favorable (1.25e-4)" "unprognostic (4.98e-3)" "unprognostic (3.15e-1)" "prognostic favorable (1.67e-5)" "unprognostic (1.09e-2)" "unprognostic (7.04e-2)" "unprognostic (8.71e-2)" "unprognostic (5.96e-2)" 11.5 11.3 11.2 10.6 13.0 16.0 11.9 13.9 12.1 11.4 8.6 10.9 8.6 13.1 11.8 10.6 11.4 8.6 10.3 10.7 11.5 11.2 12.9 10.0 12.8 12.4 11.9 14.7 8.2 15.8 8.1 8.4 12.4 11.9 10.9 12.6 9.3 11.5 14.4 12.8 9.4 13.2 12.6 12.1 9.1 8.5 11.7 14.1 11.2 13.0 15.2 11.5 9.9 16.6 26.3 20.4 24.0 20.9 25.4 19.3 18.7 20.1 18.1 26.9 26.5 20.8 10.7 33.0 14.4 25.1 14.6 15.7 31.1 24.1 29.7 38.1 14.9 24.8 33.4 24.5 22.1 43.5 22.4 20.4 27.0 24.9 17.6 20.1 22.9 22.7 23.4 20.5 22.7 12.1 34.2 46.3 33.1 19.6 21.4 28.8 19.9 17.9 20.5 19.4 20.3 17.7 27.2 19.4 13.1 18.6 18.7 15.7 24.6 17.2 19.1 25.2 23.8 9.1 18.1 38.0 19.2 20.2 12.5 23.4 13.9 11.5 12.4 15.4 13.3 12.9 14.0 11.6 15.8 11.7 13.9 14.3 8.1 12.4 17.9 20.0 12.6 10.8 11.2 13.0 13.9 12.1 10.7 11.5 12.4 11.9 12.4 12.6 11.7 16.6 45.5 25.6 31.4 17.9 48.0 53.7 45.7 41.0 43.3 29.5 23.8 22.4 30.6 30.0 39.9 20.2 37.5 34.9 72.7 19.1 21.5 32.3 29.6 41.6 42.8 38.2 28.1 24.4 23.4 24.3 36.3 37.7 17.9 47.3 39.2 32.1 21.4 29.4 30.8 23.5 25.3 19.5 44.7 29.2 40.8 8.7 32.3 40.2 23.2 14.0 39.7 34.8 32.0 21.6 28.3 27.9 20.1 25.9 28.3 33.3 18.1 31.7 44.1 39.3 19.7 53.9 44.7 41.4 30.5 36.3 57.5 57.7 43.7 37.0 23.5 35.5 SNF8 "Dot3, EAP30, VPS22" ENSG00000159210 "SNF8 subunit of ESCRT-II" Q96H20 17 48929316-48944842 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 341.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059320 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "HPA059320: AB_2683977" "unprognostic (7.85e-3)" "unprognostic (3.97e-3)" "unprognostic (2.25e-2)" "unprognostic (1.73e-1)" "unprognostic (4.39e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (7.64e-4)" "unprognostic (1.91e-1)" "unprognostic (1.58e-1)" "unprognostic (2.64e-1)" "unprognostic (1.73e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (2.81e-7)" "unprognostic (1.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.52e-1)" "unprognostic (1.38e-1)" 28.7 31.7 24.6 26.0 26.9 35.2 26.6 25.8 27.1 21.5 24.7 28.4 27.6 21.3 32.1 26.9 20.3 20.5 42.7 23.9 25.7 33.0 33.1 21.9 24.8 25.9 25.9 18.5 29.7 26.1 18.3 22.0 26.1 20.1 30.7 18.1 29.6 21.5 48.6 23.7 24.4 25.8 25.6 22.7 30.0 18.4 25.5 27.8 25.5 48.5 32.5 26.7 20.5 29.2 60.9 119.3 73.2 93.3 73.7 42.4 114.0 49.9 68.1 95.0 84.8 294.6 61.5 55.3 85.5 94.3 106.0 39.8 68.0 70.1 105.4 80.1 110.7 61.6 158.7 126.1 64.2 83.8 66.6 52.7 68.9 91.0 69.2 70.5 90.4 71.7 61.4 54.7 98.2 120.7 90.8 71.4 35.6 139.1 101.3 58.9 132.8 65.8 57.1 67.4 48.0 96.3 60.1 28.1 73.5 125.2 70.9 101.3 77.2 103.6 81.1 65.3 95.1 79.6 97.5 66.0 92.1 45.1 81.5 0.9 4.4 9.2 2.5 5.0 1.3 4.4 3.5 2.8 5.0 5.4 2.3 1.9 1.9 1.6 5.7 6.2 4.7 1.1 24.6 26.9 25.8 27.1 23.9 25.7 25.9 25.9 26.1 25.6 25.5 29.2 77.4 44.8 34.4 14.7 60.0 59.8 76.5 46.4 26.2 67.9 75.0 80.9 49.0 68.6 34.4 64.4 14.6 119.6 71.3 126.4 148.7 147.8 111.9 48.3 57.6 63.5 70.8 71.8 21.4 218.4 175.7 62.8 52.5 41.7 43.1 87.5 61.8 75.2 149.1 25.2 22.7 93.2 48.8 84.4 96.2 341.1 62.7 82.7 85.4 8.4 137.9 95.1 80.3 12.1 17.6 166.6 78.7 62.1 88.6 100.0 125.4 210.1 33.7 86.7 46.0 51.9 123.3 68.0 76.3 58.6 72.5 95.1 57.7 75.0 98.9 95.9 SNRNP48 "C6orf151, dJ336K20B.1, dJ512B11.2, FLJ32234" ENSG00000168566 "Small nuclear ribonucleoprotein U11/U12 subunit 48" Q6IEG0 6 7590198-7611967 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029234 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA029234: AB_10604097" "prognostic unfavorable (8.30e-4)" "unprognostic (3.46e-2)" "unprognostic (2.65e-1)" "unprognostic (9.65e-2)" "unprognostic (1.07e-2)" "unprognostic (1.54e-1)" "unprognostic (9.46e-3)" "unprognostic (2.55e-1)" "unprognostic (9.87e-3)" "unprognostic (1.62e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" "prognostic unfavorable (4.16e-4)" "unprognostic (1.55e-1)" "unprognostic (8.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.03e-1)" 5.4 3.8 4.8 5.5 5.1 10.4 6.9 8.5 6.7 7.0 4.4 5.4 5.7 6.4 4.6 4.7 5.7 4.0 7.2 4.6 5.0 6.0 7.3 4.5 7.3 5.7 4.9 7.7 5.7 3.7 3.6 5.3 5.9 5.8 5.5 7.3 5.3 4.4 9.7 6.3 6.7 5.4 4.7 6.1 5.4 2.7 5.1 7.1 5.8 7.1 5.9 5.6 5.8 5.9 10.0 7.9 16.2 30.3 8.5 12.5 10.9 11.2 10.4 12.0 13.1 16.9 8.1 23.6 11.8 9.4 11.5 12.6 20.2 12.1 18.2 18.2 19.8 17.0 24.1 32.7 8.9 20.5 10.9 8.8 18.3 13.5 10.2 14.2 10.5 20.8 24.1 3.6 16.8 5.7 33.7 29.6 21.9 17.1 8.8 35.8 13.9 31.6 10.8 8.7 25.0 6.8 21.8 5.6 19.6 29.7 10.9 7.2 11.8 15.8 7.1 9.5 19.6 5.8 34.6 14.5 5.3 16.1 28.9 0.1 0.7 0.4 0.7 0.5 1.2 0.6 0.8 0.9 0.9 1.1 0.7 1.3 2.3 1.1 0.3 1.0 0.7 0.6 4.8 5.1 8.5 6.7 4.6 5.0 5.7 4.9 5.9 4.7 5.1 5.9 18.6 19.2 10.3 8.1 15.7 35.7 20.2 13.6 12.0 18.7 12.6 14.6 32.1 15.7 17.3 9.2 20.9 16.3 22.7 19.2 11.7 18.0 2.5 18.0 14.8 20.5 11.4 17.7 20.4 20.1 15.6 18.0 8.2 19.6 24.1 16.8 20.3 23.4 15.9 5.0 18.8 18.2 0.0 15.1 22.1 2.5 17.7 14.9 8.8 13.1 21.7 15.5 19.6 14.6 23.8 12.1 17.9 16.6 11.5 21.4 27.1 20.1 8.5 17.8 6.6 20.9 23.2 16.1 17.0 11.5 34.0 16.3 18.5 11.2 17.1 20.1 SNRPA "Mud1, U1-A, U1A" ENSG00000077312 "Small nuclear ribonucleoprotein polypeptide A" P09012 19 40750637-40765389 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004652, HPA046440, HPA054834" Supported Supported Nucleoplasm NA NA 35000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 14: REH - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004652: AB_425687, HPA046440: AB_2679668, HPA054834: AB_2682619" "unprognostic (3.53e-2)" "prognostic favorable (2.50e-4)" "unprognostic (3.78e-2)" "unprognostic (2.10e-1)" "unprognostic (3.30e-1)" "unprognostic (5.19e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (1.03e-1)" "unprognostic (8.04e-2)" "unprognostic (9.08e-3)" "unprognostic (1.81e-1)" "unprognostic (3.38e-2)" "prognostic unfavorable (2.96e-9)" "unprognostic (2.52e-2)" "unprognostic (1.05e-1)" "unprognostic (4.80e-2)" "unprognostic (7.01e-3)" 45.3 42.1 33.3 40.8 36.6 59.9 47.0 33.8 39.6 61.7 36.1 54.4 36.4 54.8 42.6 55.1 58.4 18.2 38.6 32.7 35.7 48.2 44.9 48.5 57.1 34.5 34.5 69.2 38.0 20.5 47.7 28.7 34.4 55.0 33.8 10.8 41.1 33.0 51.0 41.2 52.7 30.2 34.5 65.2 45.9 36.5 33.9 63.5 56.2 27.6 48.2 53.8 51.7 35.0 143.4 134.6 157.2 129.4 44.2 56.8 125.9 53.8 76.8 145.5 151.9 119.4 129.8 197.2 70.1 75.6 76.2 114.2 162.0 149.6 126.7 96.7 191.5 137.0 115.2 150.0 64.9 159.8 90.0 56.1 36.6 101.4 164.6 78.2 131.7 180.1 167.5 101.2 98.5 145.4 273.7 285.1 164.1 133.1 134.8 251.6 102.0 154.5 100.8 88.4 117.8 113.4 102.4 113.4 90.6 84.3 110.1 150.8 73.8 77.4 127.8 77.5 131.2 107.4 121.6 252.9 78.0 179.3 100.0 3.2 28.0 7.5 27.6 32.2 29.2 28.1 29.2 32.4 56.5 26.4 29.6 27.9 2.5 28.0 16.2 34.7 31.8 23.0 33.3 36.6 33.8 39.6 32.7 35.7 34.5 34.5 34.4 34.5 33.9 35.0 39.3 12.8 15.2 4.9 53.0 35.9 51.6 63.7 63.7 7.2 49.8 67.2 7.2 15.7 27.0 25.8 2.1 87.1 39.6 34.9 43.0 41.6 32.7 22.7 31.1 34.2 33.0 65.4 5.4 49.4 127.0 43.7 51.0 37.6 32.4 67.0 31.4 21.9 60.1 5.0 6.5 44.9 48.8 29.9 35.0 14.6 37.3 37.5 23.2 3.7 50.4 17.8 29.9 6.0 9.5 44.6 29.4 28.2 56.6 38.9 34.6 35.2 17.5 5.1 19.7 28.2 75.7 60.7 66.2 85.1 33.1 66.4 50.9 44.3 61.2 47.7 SNRPD3 "Sm-D3, SMD3" ENSG00000100028 "Small nuclear ribonucleoprotein D3 polypeptide" P62318 22 24555958-24582052 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA001170 Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 290000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA001170: AB_1080042" "unprognostic (3.30e-1)" "unprognostic (1.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.28e-3)" "unprognostic (4.49e-2)" "unprognostic (2.03e-1)" "unprognostic (4.44e-2)" "unprognostic (1.13e-3)" "unprognostic (1.20e-2)" "unprognostic (3.52e-2)" "unprognostic (3.64e-2)" "unprognostic (2.91e-1)" "unprognostic (1.44e-1)" "unprognostic (2.87e-1)" "unprognostic (1.65e-2)" 30.5 31.1 24.7 35.2 25.7 39.2 37.5 29.6 34.8 31.8 25.7 50.5 33.2 35.5 35.5 43.5 36.7 20.2 35.3 25.0 25.8 48.0 64.9 26.9 47.7 23.7 23.9 34.3 23.7 51.2 27.0 24.7 25.5 33.8 40.7 54.1 29.7 31.9 103.7 28.8 35.7 29.5 23.6 34.3 36.5 24.7 25.0 74.4 38.9 86.2 53.3 39.5 32.3 30.7 182.5 45.7 188.6 58.5 70.1 57.7 56.1 173.1 74.8 166.1 148.1 61.4 65.8 158.7 70.1 109.2 83.0 130.7 252.1 219.3 175.5 107.9 188.8 152.4 95.4 113.9 66.2 408.0 95.7 66.5 93.8 186.3 86.6 81.8 120.6 139.8 116.2 60.5 61.5 56.8 187.0 82.6 98.9 237.8 61.9 179.5 190.7 66.6 154.5 130.0 82.2 95.6 83.4 62.7 87.7 162.7 102.3 97.5 135.5 127.0 126.3 74.3 126.2 74.3 168.2 283.7 70.1 127.1 91.4 18.5 42.9 53.9 35.6 50.2 37.6 60.5 38.4 39.2 54.2 50.7 36.6 41.3 18.6 51.1 51.1 49.7 41.1 47.4 24.7 25.7 29.6 34.8 25.0 25.8 23.7 23.9 25.5 23.6 25.0 30.7 120.0 96.1 81.8 7.5 118.2 108.6 115.3 293.1 133.1 61.1 94.2 138.8 95.9 101.5 162.9 130.6 35.5 239.5 123.1 112.6 291.6 161.9 91.0 176.6 157.7 96.8 111.0 139.4 8.1 114.8 228.8 121.0 92.2 147.9 86.2 145.3 66.0 203.3 176.4 38.7 8.7 134.2 168.9 74.5 84.8 85.1 116.2 98.1 67.6 10.3 151.0 134.3 86.5 8.0 13.4 129.4 118.2 118.5 120.7 96.8 191.7 310.5 135.2 68.9 65.7 102.8 209.6 111.1 131.4 164.9 113.7 180.3 111.9 176.2 139.0 113.3 SNW1 "Bx42, FUN20, NCoA-62, Prp45, PRPF45, SKIIP, SKIP, SKIP1" ENSG00000100603 "SNW domain containing 1" Q13573 14 77717599-77761207 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 300.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002457, CAB009931, HPA017370" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB009931: AB_2302187, HPA002457: AB_1080047, HPA017370: AB_1857339" "unprognostic (1.24e-3)" "unprognostic (2.02e-1)" "unprognostic (2.40e-1)" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (4.27e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.07e-1)" "unprognostic (8.09e-3)" "unprognostic (2.88e-2)" "unprognostic (3.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (2.47e-1)" "unprognostic (1.55e-1)" "unprognostic (4.45e-3)" "unprognostic (1.22e-2)" 47.1 33.3 27.6 33.6 29.5 91.2 42.7 30.6 35.9 39.2 29.1 38.4 32.6 39.0 28.4 38.4 38.3 26.7 39.5 27.0 29.0 38.7 33.6 37.1 46.2 29.5 28.6 41.4 38.6 31.3 30.3 33.0 29.8 32.2 32.1 43.3 34.0 21.9 64.8 50.7 38.5 30.9 28.6 44.6 36.6 48.5 28.4 49.0 33.9 35.9 41.9 38.8 38.0 32.9 91.0 66.6 67.0 70.8 54.5 60.6 76.5 61.3 54.6 66.8 61.2 66.0 81.0 88.3 54.5 46.1 50.8 88.2 81.8 58.9 90.3 71.1 63.5 71.8 59.1 66.7 77.7 50.5 81.0 46.8 76.1 60.0 82.8 71.5 65.8 83.7 103.9 64.7 51.9 93.1 90.7 85.4 74.2 103.1 87.8 97.3 85.5 61.7 61.4 82.6 71.2 76.5 84.7 73.6 87.3 68.1 106.6 95.5 69.9 71.6 81.7 64.9 73.9 62.9 95.5 98.7 65.5 79.8 80.9 94.5 71.0 95.6 57.5 76.9 65.5 59.2 64.5 65.9 72.6 67.0 67.6 63.9 67.8 94.5 92.1 43.2 94.5 76.1 27.6 29.5 30.6 35.9 27.0 29.0 29.5 28.6 29.8 28.6 28.4 32.9 86.5 93.0 49.3 13.1 64.2 56.5 80.4 89.1 33.6 56.0 40.1 50.0 49.9 47.1 77.9 53.3 35.5 79.4 75.4 38.0 76.3 79.0 43.5 97.2 81.3 69.9 43.6 85.0 17.9 70.1 100.1 64.9 26.5 80.5 92.3 61.5 55.6 33.7 76.4 38.7 18.6 50.8 54.9 53.6 52.0 24.0 77.9 70.7 39.2 30.0 95.6 66.7 65.9 15.6 31.9 71.3 43.8 74.1 46.3 48.9 48.8 57.3 88.1 72.2 65.7 60.9 89.5 300.5 140.7 39.7 54.3 109.0 76.8 54.4 47.9 70.9 SNX1 "HsT17379, MGC8664, SNX1A, Vps5" ENSG00000028528 "Sorting nexin 1" Q13596 15 64094123-64146090 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 177.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA047373, HPA052761" Approved Enhanced Endosomes,Lysosomes NA NA 6100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" "Endosomes, Lysosomes" "HPA047373: AB_2680018, HPA052761: AB_2681939" "unprognostic (3.99e-2)" "unprognostic (8.65e-3)" "unprognostic (1.96e-1)" "unprognostic (1.50e-2)" "unprognostic (7.13e-2)" "unprognostic (2.73e-1)" "unprognostic (7.15e-2)" "unprognostic (6.49e-3)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (2.47e-2)" "unprognostic (3.26e-1)" "prognostic favorable (9.88e-6)" "unprognostic (2.27e-1)" "unprognostic (3.98e-1)" "unprognostic (2.59e-2)" "unprognostic (1.95e-1)" 63.4 69.0 47.1 59.0 64.1 34.8 46.2 60.9 49.8 52.8 44.5 60.2 49.8 47.6 67.7 60.6 37.5 42.9 50.4 46.2 51.4 56.8 69.3 54.7 67.1 67.5 63.6 39.0 44.3 72.1 32.0 57.8 66.4 51.9 47.6 27.0 55.4 64.4 69.1 48.5 52.4 53.0 62.5 61.0 54.8 34.2 57.2 79.5 102.9 36.8 66.8 62.1 51.2 76.8 75.4 93.5 69.1 60.8 116.4 81.3 23.0 93.5 91.5 81.4 94.5 64.6 115.6 74.4 100.5 86.7 79.7 113.8 102.6 95.2 63.5 136.1 56.0 101.2 110.4 98.2 63.6 94.7 108.0 102.9 62.6 65.2 50.2 59.7 86.1 77.0 74.0 29.2 85.1 107.8 111.4 80.2 54.5 103.2 52.1 100.0 65.3 118.1 127.1 170.5 56.3 56.4 91.4 61.1 86.3 59.5 87.0 86.6 103.0 80.1 120.2 50.8 52.5 93.4 220.5 120.1 72.9 123.5 85.8 144.1 149.1 162.1 83.4 143.1 70.9 101.1 70.4 82.2 127.3 101.9 67.0 66.6 113.7 98.1 144.2 86.1 95.8 156.0 47.1 64.1 60.9 49.8 46.2 51.4 67.5 63.6 66.4 62.5 57.2 76.8 34.4 115.4 74.2 35.6 32.9 26.5 38.1 39.3 29.0 18.9 29.7 29.2 50.6 34.3 52.8 18.4 22.9 51.5 51.6 32.1 33.2 40.9 3.7 36.4 36.7 34.2 26.5 26.5 44.2 37.2 35.1 36.2 27.5 44.9 39.2 44.9 35.3 34.2 72.2 15.2 39.3 28.3 28.5 46.8 27.4 4.0 32.3 42.7 32.0 44.0 56.3 19.7 35.0 121.7 177.7 34.6 30.3 37.6 34.0 32.7 39.2 53.6 31.9 16.5 46.0 36.0 64.0 33.3 23.4 33.8 27.1 47.7 35.0 39.3 28.8 33.9 SNX2 ENSG00000205302 "Sorting nexin 2" O60749 5 122775079-122834543 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 349.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 290.2;naive B-cell: 289.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 79.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037400 Approved Supported Endosomes,Lysosomes NA NA 150000 "Cluster 37: B-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "Endosomes, Lysosomes" "HPA037400: AB_10670381" "unprognostic (9.26e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (2.74e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.90e-6)" "unprognostic (1.03e-1)" "unprognostic (3.86e-2)" "unprognostic (3.27e-2)" "unprognostic (4.41e-2)" "unprognostic (1.60e-1)" "prognostic favorable (8.76e-7)" "unprognostic (8.76e-2)" "unprognostic (1.01e-1)" "unprognostic (1.07e-1)" "unprognostic (8.59e-2)" 40.6 31.0 6.0 17.9 6.5 14.2 33.8 9.5 8.5 27.8 6.2 32.6 13.4 28.2 12.5 30.1 29.0 12.8 22.4 6.2 6.5 37.8 28.0 33.7 26.5 6.4 7.0 37.1 31.3 14.1 23.2 19.2 6.5 24.2 14.5 7.1 29.1 10.1 27.0 29.0 34.8 17.9 6.9 52.4 32.9 17.1 7.1 10.4 38.3 7.7 24.0 33.6 26.1 8.5 18.9 14.1 18.7 13.1 27.8 19.0 79.6 6.2 21.1 15.1 24.2 27.1 27.2 18.8 18.5 14.9 37.4 6.1 24.6 16.2 18.0 13.4 12.2 23.3 15.8 29.7 19.7 7.7 10.8 16.1 12.8 9.6 16.6 17.6 16.8 15.4 10.1 14.9 14.0 16.1 5.5 11.6 6.3 22.2 10.7 20.2 14.3 25.4 17.3 33.9 12.0 13.3 16.0 19.8 17.0 46.4 24.2 16.0 10.7 13.7 6.9 19.1 11.7 4.4 14.9 24.4 13.6 32.1 15.6 77.9 78.5 57.0 15.4 89.1 18.3 290.2 25.7 24.2 66.5 289.1 23.6 21.0 34.7 18.5 86.6 20.1 48.7 72.7 6.0 6.5 9.5 8.5 6.2 6.5 6.4 7.0 6.5 6.9 7.1 8.5 48.4 35.3 42.8 33.0 260.8 40.7 46.9 82.3 45.5 43.1 23.8 29.3 34.4 40.0 62.4 80.9 8.4 153.9 36.2 19.9 131.0 69.1 25.5 71.5 44.7 49.0 31.8 34.3 38.5 51.8 244.9 62.1 52.5 52.2 65.1 41.8 89.6 31.4 349.2 26.9 42.2 32.6 69.2 125.8 75.8 15.0 53.4 133.0 33.8 61.8 215.8 71.7 23.7 51.8 51.4 35.7 37.0 53.0 37.5 28.1 57.8 114.7 77.8 38.0 46.0 42.8 74.5 89.1 75.9 32.9 38.9 122.9 47.2 92.4 39.8 37.5 SNX6 ENSG00000129515 "Sorting nexin 6" Q9UNH7 14 34561093-34630160 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049374 Approved Supported Endosomes,Lysosomes NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Endosomes, Lysosomes" "HPA049374: AB_2680734" "unprognostic (1.89e-1)" "unprognostic (6.49e-2)" "unprognostic (1.46e-1)" "unprognostic (3.06e-2)" "unprognostic (1.12e-1)" "unprognostic (2.36e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (1.23e-1)" "unprognostic (6.63e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.68e-4)" "unprognostic (1.91e-1)" "unprognostic (3.48e-2)" "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (8.82e-2)" "unprognostic (2.10e-2)" 50.0 36.5 38.0 46.8 44.4 42.0 36.7 41.2 62.9 40.4 40.2 50.4 74.2 33.6 30.1 40.0 31.2 39.7 33.7 35.4 41.0 44.4 38.9 33.4 56.5 45.4 42.9 31.3 25.1 78.3 14.9 74.5 44.9 25.8 49.1 14.8 27.2 29.5 30.5 30.3 49.1 43.9 44.8 49.2 39.6 36.0 42.1 45.1 34.1 29.2 47.8 50.2 29.6 51.4 112.3 65.3 73.5 48.9 114.5 224.7 99.4 113.1 124.0 110.4 95.4 61.6 115.4 73.2 79.0 153.2 44.1 67.8 81.1 85.8 187.9 93.5 31.7 44.6 34.9 115.9 108.5 77.2 46.8 154.1 98.9 80.7 109.7 100.4 151.7 53.3 48.8 56.3 146.9 68.4 69.9 41.4 40.2 97.7 73.0 74.3 84.4 64.1 135.2 84.6 56.7 61.1 89.9 72.9 94.6 65.0 77.6 47.5 150.8 74.6 52.6 67.8 72.0 55.9 95.9 82.9 37.6 41.6 86.1 73.5 74.2 93.4 73.1 97.4 95.8 71.5 97.0 84.8 66.5 68.0 73.3 79.2 126.5 74.0 101.3 47.6 102.0 109.0 38.0 44.4 41.2 62.9 35.4 41.0 45.4 42.9 44.9 44.8 42.1 51.4 130.2 86.6 49.7 17.6 77.5 51.4 63.0 109.7 69.4 43.4 51.1 67.8 73.4 27.1 87.2 80.9 22.9 166.7 108.9 73.0 125.2 88.1 6.6 74.9 110.1 87.5 52.0 55.5 25.5 64.7 126.3 88.0 68.8 114.3 85.4 93.5 124.6 36.8 251.1 21.9 31.2 62.7 67.1 196.1 73.0 15.3 64.3 155.7 62.2 26.2 155.4 69.6 88.6 21.1 52.5 74.1 77.9 94.8 51.2 84.0 54.8 127.0 73.3 39.4 59.2 74.2 133.8 164.6 167.9 90.0 65.8 254.6 109.4 346.2 82.0 76.8 SPTLC2 "hLCB2a, KIAA0526, LCB2, LCB2A" ENSG00000100596 "Serine palmitoyltransferase long chain base subunit 2" O15270 14 77505997-77616637 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 164.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA No "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "unprognostic (3.16e-1)" "unprognostic (2.82e-2)" "unprognostic (1.24e-1)" "unprognostic (4.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (1.46e-2)" "unprognostic (3.09e-1)" "unprognostic (4.05e-1)" "unprognostic (1.98e-2)" "unprognostic (2.51e-1)" "prognostic favorable (6.69e-8)" "unprognostic (1.29e-2)" "unprognostic (2.35e-1)" "unprognostic (4.94e-2)" "unprognostic (1.32e-1)" 17.6 12.2 14.6 12.6 26.7 33.7 18.3 24.0 19.4 15.2 9.9 18.5 14.5 10.5 7.6 22.8 14.2 11.8 6.7 15.3 18.1 17.6 7.7 13.1 12.0 30.7 21.5 10.4 5.7 10.7 6.2 20.4 31.5 8.4 19.8 14.2 13.7 8.8 3.9 12.2 17.4 11.6 25.3 19.6 20.4 5.0 21.7 10.3 10.9 6.1 13.3 15.0 10.8 52.7 28.9 18.5 14.1 15.5 14.3 17.8 23.7 41.7 30.8 28.2 29.3 23.7 62.3 28.8 10.4 42.7 14.5 34.7 38.1 23.7 42.5 12.6 11.0 82.5 13.4 14.3 12.1 8.4 25.8 11.7 11.4 18.4 20.4 16.3 40.6 19.4 16.2 13.5 16.2 24.9 22.2 28.7 9.2 45.4 16.8 23.5 14.3 10.0 32.9 63.4 13.6 17.1 15.0 50.3 15.8 24.7 61.8 15.3 25.9 25.7 18.2 9.6 9.7 7.6 13.4 19.1 17.3 29.4 14.8 18.3 31.3 27.1 6.1 24.2 5.7 6.7 5.1 6.8 31.2 7.9 3.5 5.8 19.1 17.7 31.8 11.1 6.0 13.4 14.6 26.7 24.0 19.4 15.3 18.1 30.7 21.5 31.5 25.3 21.7 52.7 125.1 28.9 27.3 24.8 27.3 32.4 28.3 27.0 15.4 15.7 24.3 18.4 8.9 15.7 30.7 47.8 35.5 11.9 28.3 37.6 1.9 24.0 1.6 44.1 36.0 53.1 13.2 51.3 31.2 16.1 12.3 18.9 43.3 36.0 51.3 37.2 68.2 7.2 25.1 5.0 29.5 39.3 20.3 75.9 19.8 1.7 14.6 66.2 19.6 83.4 51.3 8.8 32.0 59.3 164.0 35.0 30.4 15.8 11.0 27.0 28.4 8.8 33.5 20.0 32.9 10.5 25.5 7.3 19.0 37.7 29.1 6.6 23.3 14.6 33.0 60.0 SRA1 "SRA, STRAA1" ENSG00000213523 "Steroid receptor RNA activator 1" Q9HD15 5 140537340-140558252 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Activator, Receptor, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044598, HPA050153" Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA044598: AB_2679013, HPA050153: AB_2681033" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (8.69e-2)" "prognostic favorable (8.01e-6)" "unprognostic (9.32e-2)" "unprognostic (2.56e-1)" "unprognostic (2.90e-1)" "unprognostic (2.43e-1)" "unprognostic (9.38e-2)" "unprognostic (7.41e-2)" "unprognostic (5.58e-3)" "unprognostic (2.61e-1)" "unprognostic (5.34e-2)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (3.71e-1)" "unprognostic (1.04e-1)" 12.2 34.0 8.7 7.7 9.0 9.6 9.7 15.8 12.3 10.0 9.2 12.5 5.1 8.2 6.0 9.3 9.4 5.6 12.0 9.9 9.3 12.4 25.8 15.0 6.3 8.4 8.2 14.9 7.5 4.7 22.2 5.8 8.8 12.5 4.7 7.2 14.8 6.2 14.5 9.4 11.9 5.4 8.6 17.6 14.0 22.6 8.9 5.6 12.9 2.5 5.2 9.4 8.8 9.2 9.7 22.7 11.8 12.3 5.6 7.6 16.4 16.1 9.1 10.3 10.8 41.8 5.9 8.2 11.7 6.2 5.5 6.4 2.1 12.0 4.1 12.7 13.9 7.2 25.0 16.1 12.0 13.1 9.4 14.7 6.1 5.5 2.8 9.1 4.7 13.8 7.4 12.1 6.9 29.5 10.7 20.4 3.6 5.2 18.0 11.7 10.0 7.9 5.4 11.3 8.3 9.8 9.4 8.5 11.6 4.1 10.5 14.7 7.5 9.7 5.1 8.5 13.2 15.1 10.9 8.6 12.0 16.8 6.5 16.1 26.0 20.3 10.7 23.8 9.9 15.8 10.2 10.4 25.2 14.0 8.2 9.4 43.0 13.6 23.6 15.2 19.5 26.8 8.7 9.0 15.8 12.3 9.9 9.3 8.4 8.2 8.8 8.6 8.9 9.2 43.3 6.4 49.4 13.4 46.7 52.4 68.5 126.1 38.7 23.6 57.8 48.9 71.7 57.2 86.4 33.1 8.4 103.7 56.9 87.8 113.5 102.7 104.6 59.5 33.4 39.8 38.4 35.1 15.5 148.2 117.9 48.6 64.7 43.1 68.4 21.8 42.1 69.7 93.1 15.2 17.2 71.6 107.8 61.2 71.5 150.0 25.1 82.0 67.6 7.5 90.4 59.5 42.2 9.0 11.5 186.0 78.7 29.7 113.7 82.9 83.7 131.0 84.1 23.7 26.3 26.7 76.1 77.2 30.7 62.3 45.9 179.0 47.4 66.8 49.2 142.6 SSU72 HSPC182 ENSG00000160075 "SSU72 homolog, RNA polymerase II CTD phosphatase" Q9NP77 1 1541673-1574863 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA processing" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 700.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069290, HPA070604" Supported Approved Nucleoplasm,Cytosol No No "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA069290: AB_2686108, HPA070604: AB_2686285" "unprognostic (3.33e-2)" "unprognostic (2.79e-2)" "unprognostic (6.37e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "unprognostic (9.84e-2)" "unprognostic (2.40e-3)" "unprognostic (2.43e-2)" "unprognostic (3.23e-1)" "unprognostic (3.23e-1)" "unprognostic (6.75e-2)" "unprognostic (1.36e-1)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "unprognostic (8.51e-2)" "unprognostic (3.77e-1)" "unprognostic (1.06e-1)" 105.4 77.3 101.9 64.1 107.4 61.0 94.8 101.9 119.7 82.1 112.6 95.9 75.1 80.4 88.3 123.3 80.6 52.7 131.5 106.2 113.3 105.5 122.4 87.9 74.3 106.6 106.6 81.9 115.0 63.4 99.9 52.0 109.0 86.8 62.7 52.1 100.6 53.6 246.7 100.2 90.8 53.8 103.4 105.9 96.1 58.9 113.2 65.1 107.8 136.3 67.7 83.6 87.2 103.9 204.6 127.6 90.2 140.3 152.1 145.4 92.2 172.8 134.1 147.6 152.5 120.8 229.7 205.4 92.1 137.0 143.7 155.0 147.4 142.5 142.8 172.8 173.9 129.3 110.7 193.8 171.5 165.6 108.4 130.7 117.8 158.4 149.8 123.2 140.1 122.6 227.9 154.1 118.6 181.4 190.8 264.5 158.5 198.9 191.5 149.5 145.5 289.8 163.7 61.8 166.1 114.0 117.1 296.3 535.3 152.0 154.6 142.0 107.8 140.8 89.2 160.9 150.7 186.5 241.2 258.1 148.0 260.1 69.9 143.4 93.0 188.6 80.0 98.9 99.3 120.7 105.9 95.9 100.2 117.7 127.6 105.1 204.1 75.3 91.7 62.9 161.5 101.0 101.9 107.4 101.9 119.7 106.2 113.3 106.6 106.6 109.0 103.4 113.2 103.9 107.5 28.9 72.7 14.7 130.6 186.2 138.9 100.0 108.1 95.9 169.6 173.7 92.4 151.5 69.2 101.2 20.9 208.6 129.9 171.2 291.6 76.3 283.0 107.8 77.6 91.5 142.0 78.8 23.3 106.6 239.4 84.4 89.7 101.0 61.5 90.6 98.6 132.7 141.1 112.7 23.8 165.8 83.4 178.4 130.0 700.2 104.7 123.3 167.2 15.9 144.8 152.3 193.6 25.6 20.1 91.9 206.7 85.7 132.5 199.6 242.8 325.8 59.0 73.4 59.2 77.6 136.6 97.1 157.4 155.9 220.4 245.3 128.1 86.2 172.1 153.2 SUGT1 SGT1 ENSG00000165416 "SGT1 homolog, MIS12 kinetochore complex assembly cochaperone" Q9Y2Z0 13 52652709-52700909 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015942, HPA043949" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 17000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB015942: , HPA043949: AB_2678745" "unprognostic (3.66e-2)" "unprognostic (3.98e-2)" "unprognostic (3.57e-1)" "unprognostic (1.22e-1)" "unprognostic (3.77e-2)" "prognostic unfavorable (8.69e-4)" "unprognostic (2.24e-1)" "unprognostic (2.96e-1)" "unprognostic (3.76e-1)" "unprognostic (1.96e-3)" "unprognostic (9.51e-2)" "unprognostic (1.12e-1)" "unprognostic (6.83e-2)" "unprognostic (2.82e-3)" "unprognostic (9.05e-2)" "unprognostic (2.93e-2)" "unprognostic (1.56e-1)" 27.4 31.4 33.4 25.5 38.1 32.0 23.6 38.6 55.6 23.0 33.1 25.5 27.3 19.6 20.3 30.1 19.4 19.6 37.0 34.8 37.0 31.7 36.5 22.5 27.4 34.8 34.8 21.5 30.6 19.8 26.9 25.9 36.9 19.6 26.9 22.2 25.2 16.3 29.6 24.5 26.8 22.1 35.3 23.2 26.8 34.5 36.4 29.8 21.1 28.1 29.9 27.3 24.3 48.1 47.0 50.2 72.9 55.6 70.4 57.0 69.8 100.8 66.3 61.7 49.0 110.3 114.7 102.4 27.9 62.8 89.5 79.0 90.6 57.9 90.0 85.3 37.7 95.1 65.8 84.4 51.1 74.8 68.7 40.0 51.7 63.9 48.2 79.0 105.0 64.8 90.5 32.7 95.7 33.4 70.3 136.6 85.3 183.9 47.8 79.6 42.4 44.4 108.0 51.7 24.1 30.7 52.1 42.2 49.8 82.6 43.5 70.3 76.1 51.3 59.9 59.6 87.6 25.7 38.9 91.5 30.8 59.2 75.5 63.6 29.0 49.0 24.3 34.5 23.9 30.9 31.4 33.2 32.9 30.3 23.8 26.6 4.1 33.2 34.1 41.0 46.0 25.2 33.4 38.1 38.6 55.6 34.8 37.0 34.8 34.8 36.9 35.3 36.4 48.1 82.1 38.5 36.0 22.2 46.1 39.8 65.4 68.2 38.1 52.6 40.6 55.8 126.2 32.9 51.8 51.5 25.0 67.0 78.3 52.3 78.2 88.3 185.6 112.0 79.0 65.9 34.1 65.2 19.9 89.0 143.0 60.9 50.0 75.1 36.8 49.7 43.5 38.3 97.8 50.5 23.0 58.2 54.9 44.5 43.9 95.7 58.7 54.3 48.0 13.1 123.7 91.8 58.7 21.1 47.6 85.2 55.0 59.8 58.3 44.1 74.3 100.9 67.8 56.6 26.3 72.4 92.1 146.7 101.0 45.7 43.2 74.4 61.1 56.1 55.5 52.3 SUMO1 "GMP1, OFC10, PIC1, SMT3C, SMT3H3, SUMO-1, UBL1" ENSG00000116030 "Small ubiquitin like modifier 1" P63165 2 202206182-202238599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 7.6" "CAB004269, HPA056956" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nuclear bodies" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear membrane" "Nucleoli, Nuclear bodies" "CAB004269: AB_628300, HPA056956: AB_2683285" "unprognostic (7.15e-2)" "unprognostic (2.34e-2)" "unprognostic (1.49e-1)" "unprognostic (2.52e-3)" "unprognostic (2.89e-1)" "unprognostic (9.56e-3)" "unprognostic (1.76e-2)" "unprognostic (8.08e-2)" "unprognostic (1.78e-3)" "prognostic favorable (7.93e-4)" "unprognostic (7.06e-3)" "unprognostic (1.16e-1)" "unprognostic (4.64e-3)" "unprognostic (1.31e-2)" "unprognostic (7.58e-2)" "unprognostic (2.82e-2)" "unprognostic (2.19e-1)" 77.5 99.1 79.4 62.7 84.9 133.7 83.6 89.0 99.9 68.9 84.4 82.7 72.0 65.1 86.3 71.6 65.7 71.7 79.8 85.6 85.3 118.1 174.1 66.5 86.4 79.9 80.1 54.5 55.8 91.6 56.7 75.6 81.1 75.3 82.8 80.2 66.8 61.9 107.5 57.1 80.5 71.5 78.9 68.1 73.8 54.7 81.4 112.1 102.3 103.3 95.4 77.9 54.9 86.6 164.1 82.4 291.4 155.8 159.3 168.5 129.7 171.0 214.6 209.0 274.6 178.1 203.7 111.6 153.5 199.0 193.5 117.1 242.2 237.9 325.0 104.8 185.7 207.6 159.0 211.2 114.9 237.2 188.5 130.9 225.2 164.0 123.9 195.1 197.3 219.0 194.2 176.0 226.4 141.1 298.3 391.6 351.7 168.5 172.2 190.9 163.2 197.9 255.5 134.3 201.7 219.3 140.3 133.6 236.4 313.9 120.0 223.2 139.9 152.5 153.0 141.4 152.8 151.7 322.9 285.8 170.2 165.4 137.2 242.2 220.0 284.2 169.2 226.5 179.6 276.3 206.8 200.0 223.6 231.6 193.8 202.3 256.5 246.5 239.7 187.8 329.0 394.7 79.4 84.9 89.0 99.9 85.6 85.3 79.9 80.1 81.1 78.9 81.4 86.6 182.7 112.2 61.1 10.7 143.1 422.1 204.4 448.6 177.6 99.6 196.8 170.2 58.1 130.1 215.3 189.4 64.6 259.4 162.3 136.6 481.3 250.4 91.3 148.3 115.1 170.7 142.4 140.1 31.4 173.3 297.8 161.8 89.7 115.2 92.6 114.7 142.8 202.1 205.3 87.5 27.8 156.4 319.4 140.7 330.2 28.0 129.8 137.7 211.7 15.9 241.3 182.3 176.1 16.6 21.2 208.1 191.1 127.9 130.5 258.5 272.2 534.4 185.5 87.8 111.7 92.5 221.9 212.0 141.5 183.9 424.5 209.7 174.5 134.9 157.5 254.1 SUMO2 "SMT3B, SMT3H2" ENSG00000188612 "Small ubiquitin like modifier 2" P61956 17 75165586-75182959 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037314, HPA042123, HPA048064" Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear bodies" "CAB037314: AB_796170, HPA042123: AB_2677860, HPA048064: AB_2680244" "unprognostic (6.49e-2)" "unprognostic (1.01e-2)" "unprognostic (4.23e-2)" "prognostic unfavorable (1.88e-5)" "unprognostic (1.32e-1)" "unprognostic (1.23e-3)" "prognostic unfavorable (2.12e-4)" "unprognostic (9.80e-2)" "unprognostic (6.02e-3)" "unprognostic (2.58e-3)" "unprognostic (5.07e-2)" "unprognostic (2.29e-2)" "prognostic unfavorable (5.23e-6)" "unprognostic (2.15e-1)" "unprognostic (1.25e-1)" "unprognostic (1.14e-2)" "unprognostic (4.89e-3)" 198.2 205.1 176.2 203.6 186.9 229.8 174.5 214.2 239.9 219.3 168.5 190.1 161.4 205.5 158.5 240.9 186.8 134.0 156.7 185.4 193.4 205.6 185.8 171.5 214.6 175.5 177.3 231.1 161.0 130.6 146.5 130.1 177.5 158.1 143.9 205.9 160.3 122.2 229.4 182.6 169.2 154.8 187.4 174.7 205.3 182.2 187.2 271.9 149.2 152.0 228.6 188.2 205.1 191.5 742.5 299.1 1035.7 534.4 296.8 283.6 486.1 571.2 276.9 384.5 354.5 343.6 396.0 641.8 398.1 327.9 503.0 353.4 470.3 351.7 451.6 373.6 712.4 644.0 282.1 597.4 194.1 856.1 555.7 290.1 195.9 343.9 187.2 615.6 403.8 628.3 540.7 508.7 288.3 317.8 1310.8 734.0 632.8 552.5 445.5 903.2 987.1 539.5 391.9 612.0 633.4 739.0 691.1 566.8 481.4 796.9 614.6 663.0 458.1 557.2 581.7 429.4 931.3 355.4 348.1 986.8 351.2 500.6 457.3 831.1 436.4 781.2 390.9 498.9 408.8 515.7 486.8 456.8 451.6 443.6 444.0 437.1 380.1 452.3 548.3 616.0 701.6 851.5 176.2 186.9 214.2 239.9 185.4 193.4 175.5 177.3 177.5 187.4 187.2 191.5 522.1 163.5 160.6 25.5 453.3 705.4 647.4 717.6 602.2 216.4 492.1 524.1 62.3 337.5 368.2 355.0 50.1 522.8 485.0 278.1 968.5 602.7 281.8 348.6 429.0 458.5 441.9 519.9 35.7 531.7 948.9 451.1 274.2 343.5 349.0 465.0 491.2 273.4 616.3 233.9 33.0 397.9 472.0 676.9 637.0 488.6 604.9 481.5 462.4 21.5 743.4 535.4 517.0 25.1 42.6 666.5 397.3 605.2 443.0 822.3 348.7 847.5 322.6 161.3 571.9 409.5 716.6 872.2 683.2 795.2 742.7 565.2 480.3 476.1 437.0 977.2 SUPT16H "CDC68, FACT, FACTP140, FLJ10857, FLJ14010, SPT16/CDC68" ENSG00000092201 "SPT16 homolog, facilitates chromatin remodeling subunit" Q9Y5B9 14 21351476-21384019 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022551, HPA049787" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA 27000 "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "CAB022551: , HPA049787: AB_2680881" "unprognostic (1.65e-1)" "unprognostic (2.22e-1)" "unprognostic (3.52e-2)" "unprognostic (7.12e-2)" "unprognostic (7.32e-2)" "unprognostic (1.22e-2)" "unprognostic (1.38e-3)" "unprognostic (1.86e-1)" "unprognostic (7.65e-2)" "unprognostic (4.91e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (6.48e-3)" "unprognostic (1.02e-1)" "unprognostic (7.58e-3)" "unprognostic (9.05e-2)" "unprognostic (5.87e-3)" 29.3 24.8 9.7 36.6 11.1 42.3 35.9 18.8 13.9 34.2 8.2 30.6 23.1 41.1 19.5 29.0 32.0 24.1 24.1 9.7 15.6 28.6 22.4 26.3 51.2 11.3 12.0 43.6 22.6 46.2 13.5 32.1 12.0 29.9 35.1 44.4 20.9 32.6 21.8 28.9 25.9 36.6 10.7 32.9 26.3 43.3 12.1 56.8 33.3 24.6 51.8 35.6 20.1 12.3 147.8 136.9 185.5 136.6 85.5 81.7 131.4 130.3 103.2 155.5 145.4 133.9 129.5 311.3 48.5 96.5 99.7 153.9 237.2 118.9 234.0 99.8 100.9 188.7 121.9 195.1 87.0 270.1 134.7 73.4 72.6 131.0 146.3 75.4 107.7 174.2 158.1 129.4 131.3 99.9 253.6 85.8 207.1 136.2 134.1 270.3 210.6 168.0 63.9 160.8 183.8 157.2 209.8 125.3 81.1 118.7 69.2 127.9 91.1 135.0 113.4 85.0 143.3 128.8 230.2 306.7 49.9 158.0 104.9 35.6 18.3 28.2 29.6 23.9 34.7 31.2 27.9 33.2 23.7 27.4 31.3 32.2 15.0 34.0 31.1 22.2 28.4 25.2 9.7 11.1 18.8 13.9 9.7 15.6 11.3 12.0 12.0 10.7 12.1 12.3 41.5 64.1 55.9 24.2 51.6 35.6 44.3 51.5 45.5 48.9 46.3 49.7 64.2 22.8 50.3 53.3 47.9 65.1 73.6 28.4 25.4 71.0 142.5 52.0 124.3 46.9 23.4 74.6 27.4 61.1 63.9 61.1 29.6 61.7 84.2 73.4 29.3 32.0 41.9 55.5 30.1 31.2 40.7 34.9 25.2 96.1 59.7 40.7 17.8 20.6 90.9 53.3 64.9 16.1 25.2 68.9 15.2 59.8 39.5 46.1 16.5 30.4 40.2 41.1 19.7 78.5 69.5 128.9 152.8 45.1 41.5 45.6 56.3 61.6 43.0 35.7 SUZ12 "CHET9, JJAZ1, KIAA0160" ENSG00000178691 "SUZ12 polycomb repressive complex 2 subunit" Q15022 17 31937007-32001038 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057436 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim, Nuclear bodies" "HPA057436: AB_2683439" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (3.65e-3)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (7.31e-2)" "unprognostic (2.66e-3)" "unprognostic (8.05e-2)" "unprognostic (7.27e-2)" "unprognostic (3.06e-2)" "unprognostic (6.29e-2)" "unprognostic (8.70e-2)" "unprognostic (3.28e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (5.91e-2)" "unprognostic (1.31e-1)" 12.3 11.8 6.3 18.8 6.3 45.4 15.0 11.1 8.5 11.6 6.8 14.9 16.0 15.2 12.0 14.0 11.0 12.0 10.3 5.4 5.8 16.4 18.1 12.6 33.0 5.4 5.9 11.4 11.5 19.8 6.6 18.7 5.6 13.3 16.4 26.5 10.5 12.2 8.1 13.0 15.3 14.7 5.2 18.4 15.2 27.4 6.1 38.5 18.3 11.0 30.0 15.6 9.0 7.1 46.5 40.4 37.2 42.9 21.1 26.8 38.2 44.2 38.8 53.0 63.7 30.9 25.5 100.7 33.2 27.7 45.4 40.1 56.0 25.5 85.7 35.8 54.0 69.9 32.9 22.3 24.8 111.5 68.7 18.7 28.1 53.1 40.4 32.1 33.1 47.3 68.8 135.6 46.2 16.2 133.3 64.4 21.3 32.4 24.4 78.5 95.3 81.9 31.1 44.6 47.5 37.1 71.3 22.7 43.3 25.8 66.0 91.5 24.7 41.9 38.0 50.8 69.3 73.5 98.4 122.5 30.7 67.4 38.7 0.6 0.7 1.6 1.4 1.1 1.1 2.4 1.6 1.6 0.6 1.8 1.5 2.1 1.6 1.8 0.7 1.9 1.8 0.4 6.3 6.3 11.1 8.5 5.4 5.8 5.4 5.9 5.6 5.2 6.1 7.1 44.5 41.7 45.8 43.1 50.1 58.5 50.2 21.8 31.9 77.6 54.2 36.8 32.3 27.1 32.6 35.0 108.4 61.5 65.2 24.0 17.6 28.3 16.2 52.8 55.8 45.1 29.4 93.6 71.6 21.9 53.1 35.1 31.1 54.2 15.8 41.4 38.2 42.3 32.9 62.2 69.5 31.8 10.2 42.1 58.2 13.9 26.8 47.3 24.9 45.0 73.1 45.7 38.1 75.4 71.3 27.8 15.4 25.6 66.2 62.8 21.5 26.6 29.6 80.9 13.1 47.2 38.4 121.7 128.9 48.6 71.7 69.5 52.5 52.8 35.6 66.7 SYNCRIP "dJ3J17.2, GRY-RBP, hnRNP-Q, HNRNPQ, HNRPQ1, NSAP1" ENSG00000135316 "Synaptotagmin binding cytoplasmic RNA interacting protein" O60506 6 85607779-85644063 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Translation regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010895, HPA041275, HPA069241" Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA 1300000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Vesicles, Cytosol" "CAB010895: AB_261964, HPA041275: AB_2677389, HPA069241: " "unprognostic (1.01e-1)" "unprognostic (3.49e-2)" "unprognostic (1.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-2)" "unprognostic (6.22e-2)" "prognostic unfavorable (6.28e-5)" "unprognostic (6.84e-2)" "unprognostic (6.48e-2)" "prognostic favorable (5.59e-4)" "unprognostic (1.58e-2)" "unprognostic (1.43e-1)" "unprognostic (4.86e-2)" "unprognostic (1.37e-1)" "unprognostic (2.34e-1)" "unprognostic (1.00e-1)" "unprognostic (4.11e-1)" 60.5 43.2 25.1 80.2 28.0 67.3 55.6 28.1 24.8 51.4 26.0 54.1 48.0 46.1 41.7 75.8 34.0 47.8 45.6 22.8 29.9 53.1 66.7 49.4 88.1 28.9 27.4 36.2 51.9 56.9 19.5 68.5 31.0 44.9 62.7 36.0 41.4 46.5 55.9 43.5 44.0 62.1 27.7 51.3 50.0 38.7 27.6 91.0 87.3 56.0 101.9 81.5 40.8 29.0 209.5 147.5 239.9 157.1 150.8 165.3 162.8 258.6 218.1 244.4 239.9 250.4 132.6 480.0 200.0 262.8 203.1 197.4 331.1 269.0 405.4 175.9 163.9 405.4 152.8 165.2 130.3 497.6 177.7 141.8 179.6 276.4 272.1 138.4 254.9 133.2 451.5 210.0 295.1 243.5 255.2 218.9 231.5 209.4 153.2 364.7 345.5 209.9 236.2 307.1 239.5 184.6 188.5 180.8 128.6 137.2 150.8 360.9 247.4 165.8 142.7 189.8 374.2 138.0 260.5 275.4 165.4 328.7 251.4 1.8 24.7 8.8 30.6 36.2 30.0 21.9 27.1 27.5 37.7 21.2 23.4 27.7 3.0 36.1 41.1 29.0 31.6 24.6 25.1 28.0 28.1 24.8 22.8 29.9 28.9 27.4 31.0 27.7 27.6 29.0 106.9 115.4 119.5 26.4 73.0 148.2 160.9 124.4 83.6 44.5 89.0 82.8 88.9 52.9 126.7 46.0 16.7 101.3 97.2 50.4 54.8 120.7 117.6 105.1 156.2 100.7 56.7 65.6 24.0 99.6 133.3 101.8 79.5 152.1 61.4 81.6 57.5 81.4 96.9 62.2 24.3 78.0 79.3 71.1 67.1 28.7 73.7 92.9 53.4 31.9 90.7 45.1 57.7 32.2 40.9 130.0 45.7 64.3 97.4 133.0 47.7 80.7 84.6 42.2 19.7 158.6 131.8 93.7 65.8 142.4 141.6 118.1 81.6 85.8 106.7 159.8 SYS1 "C20orf169, dJ453C12.4" ENSG00000204070 "SYS1 golgi trafficking protein" Q8N2H4 20 45361937-45376798 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046716 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA046716: AB_2679769" "unprognostic (8.24e-2)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.51e-2)" "unprognostic (1.04e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (2.10e-2)" "unprognostic (1.63e-2)" "unprognostic (4.77e-1)" "unprognostic (4.66e-3)" "unprognostic (2.33e-1)" "unprognostic (4.28e-2)" "unprognostic (4.90e-2)" "unprognostic (4.38e-2)" "unprognostic (5.38e-3)" "unprognostic (2.01e-2)" 19.7 18.4 15.9 16.4 18.4 25.5 18.2 16.9 16.7 19.2 45.1 21.2 11.6 21.6 17.6 16.1 33.0 18.8 16.5 17.3 18.6 23.6 24.9 19.8 26.7 16.7 17.4 25.1 19.2 23.2 16.4 16.0 17.1 14.9 14.5 21.5 26.1 19.6 23.4 12.7 18.1 16.9 16.0 15.3 20.4 8.5 18.4 16.4 29.8 15.8 24.3 19.0 15.6 19.9 16.8 30.4 12.9 22.0 40.2 24.6 20.4 17.3 24.3 25.5 21.8 76.1 32.0 10.5 39.1 28.7 32.8 35.8 25.6 30.5 17.8 15.1 13.9 12.3 16.6 41.5 33.4 23.0 23.9 30.1 44.6 28.0 17.7 25.6 25.6 18.6 19.3 15.3 18.9 36.6 19.0 23.1 13.8 20.2 42.2 3.1 15.0 16.3 30.6 14.5 9.8 11.8 27.5 16.6 34.2 13.3 37.3 14.6 15.1 32.2 21.3 17.9 16.3 18.1 13.0 4.1 22.0 15.5 18.7 51.8 23.4 37.7 33.8 23.4 35.7 26.3 32.5 34.8 26.4 31.3 35.1 30.6 29.7 22.9 25.6 103.9 37.8 30.6 15.9 18.4 16.9 16.7 17.3 18.6 16.7 17.4 17.1 16.0 18.4 19.9 18.5 19.2 28.1 0.0 39.5 29.1 37.6 24.6 19.9 25.3 29.9 25.4 12.7 27.1 17.3 23.9 29.2 28.4 61.1 31.7 17.6 39.6 30.3 48.7 15.8 23.1 16.1 7.6 0.0 57.9 45.2 26.8 9.2 28.5 26.1 15.0 24.7 34.5 60.6 20.2 0.0 22.6 22.4 38.4 15.4 19.9 17.4 30.3 24.9 0.0 24.4 34.3 35.0 0.0 0.0 42.0 28.5 19.2 14.8 36.2 47.5 29.4 58.4 37.1 13.1 21.0 33.2 17.4 13.8 16.6 30.5 52.5 37.2 18.9 17.1 39.4 TAF10 "TAF2A, TAF2H, TAFII30" ENSG00000166337 "TATA-box binding protein associated factor 10" Q12962 11 6606294-6612539 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 361.8;Late spermatids: 1039.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004148, CAB022405" Supported Supported Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB022405: , HPA004148: AB_1857736" "unprognostic (1.69e-3)" "unprognostic (2.32e-1)" "unprognostic (3.19e-2)" "unprognostic (6.21e-3)" "unprognostic (9.10e-2)" "unprognostic (6.99e-2)" "unprognostic (5.24e-3)" "unprognostic (9.03e-3)" "unprognostic (1.12e-1)" "unprognostic (1.24e-2)" "unprognostic (3.46e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.38e-1)" "unprognostic (2.55e-1)" "unprognostic (9.64e-3)" "unprognostic (3.80e-3)" 78.9 140.7 147.5 53.3 150.3 93.0 69.2 149.2 204.1 59.3 142.6 66.2 44.3 63.6 97.5 103.1 61.7 28.3 130.0 147.7 156.2 100.9 151.6 76.7 56.8 157.1 153.2 50.0 152.8 53.2 96.2 31.0 155.9 79.8 54.1 30.8 69.6 42.9 107.5 61.2 68.1 38.7 147.7 125.4 100.1 190.7 149.9 82.0 74.6 50.0 76.3 72.1 58.3 150.9 82.4 138.2 88.7 77.7 140.6 135.1 67.5 61.4 134.6 98.9 98.6 102.0 145.0 45.4 77.2 111.4 137.4 68.6 66.0 99.7 97.3 92.2 95.3 64.2 95.6 122.2 227.7 85.4 98.9 157.8 125.1 77.5 163.0 168.0 110.6 139.5 67.0 80.7 157.4 159.5 122.2 78.5 62.6 130.9 107.6 72.2 46.8 78.5 163.5 108.1 62.2 84.4 82.9 95.0 107.6 129.8 67.1 100.6 64.6 67.2 78.9 97.6 87.9 94.6 70.7 73.4 110.4 44.5 108.2 12.7 9.9 11.8 9.7 15.7 8.8 9.8 9.4 11.1 10.8 11.6 8.8 7.8 27.9 8.7 16.2 23.7 11.4 5.1 147.5 150.3 149.2 204.1 147.7 156.2 157.1 153.2 155.9 147.7 149.9 150.9 106.4 3.2 23.3 6.2 60.1 21.4 56.8 9.4 32.5 23.0 116.3 148.0 51.5 47.1 13.1 36.8 20.9 48.5 130.7 79.7 19.6 18.2 361.8 93.8 90.0 39.3 34.7 45.4 4.4 33.3 55.2 43.0 56.6 86.3 5.1 70.5 26.7 53.8 65.9 23.5 4.4 50.8 2.0 78.4 44.4 1039.1 24.5 91.2 26.6 9.4 36.3 84.7 53.5 2.5 9.9 30.7 68.5 19.2 89.6 85.8 55.5 43.1 14.0 27.1 0.0 36.3 50.0 108.8 33.2 75.0 29.1 53.6 65.0 124.1 44.2 88.7 TAOK1 "FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO1" ENSG00000160551 "TAO kinase 1" Q7L7X3 17 29390363-29551903 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 220.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007669 Approved Uncertain Vesicles NA NA 1600000 "Cluster 1: Neutrophils - Mixed function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA007669: AB_1080201" "unprognostic (1.46e-1)" "unprognostic (7.15e-3)" "unprognostic (2.70e-2)" "unprognostic (1.52e-1)" "unprognostic (1.81e-2)" "unprognostic (4.85e-2)" "unprognostic (1.28e-2)" "unprognostic (4.31e-2)" "unprognostic (1.15e-1)" "unprognostic (6.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (2.85e-2)" "unprognostic (5.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.66e-1)" "unprognostic (2.62e-1)" 13.7 9.1 12.0 9.8 16.0 10.5 10.3 13.8 13.1 11.8 1.2 9.5 5.2 10.8 8.5 10.3 7.9 9.6 13.2 13.3 12.8 10.2 8.6 9.8 9.9 16.4 14.5 10.3 7.8 19.4 8.0 11.7 14.9 9.0 8.5 20.9 7.8 10.0 11.4 10.4 7.3 11.7 13.2 10.4 8.1 11.7 13.9 13.2 14.5 15.2 9.5 12.1 8.7 20.4 19.3 35.0 32.1 13.4 24.1 29.8 11.3 20.0 23.9 20.3 21.1 20.7 7.9 13.8 15.8 35.9 20.7 16.3 30.4 15.7 36.4 20.7 18.2 21.0 21.3 12.2 16.6 26.5 16.7 19.4 19.6 29.0 30.6 21.3 27.3 14.0 20.7 12.0 26.7 14.2 18.5 9.5 12.0 12.9 8.6 15.1 41.2 8.8 19.1 31.5 16.1 18.7 34.6 34.4 21.1 32.6 23.6 21.6 33.6 28.0 19.7 23.7 27.5 9.3 18.6 14.0 20.3 14.8 24.3 0.6 0.5 0.5 0.6 0.6 0.5 0.5 0.6 0.7 0.5 0.6 0.7 0.7 1.7 0.5 0.6 1.4 0.4 0.3 12.0 16.0 13.8 13.1 13.3 12.8 16.4 14.5 14.9 13.2 13.9 20.4 96.9 48.1 45.8 105.8 35.9 44.5 27.4 27.0 52.9 56.6 35.5 23.2 90.2 30.0 37.7 46.0 98.0 18.7 40.5 29.3 15.6 27.3 11.8 45.0 72.0 55.4 37.7 18.7 162.3 24.3 16.0 58.0 31.6 80.1 28.5 44.3 52.1 29.5 30.1 52.2 160.5 23.7 24.4 65.6 60.4 19.8 39.7 67.3 40.9 92.8 55.8 37.1 29.9 142.2 220.8 38.9 24.0 54.2 34.2 40.4 17.6 22.1 31.0 54.7 26.3 66.1 52.1 59.1 33.2 49.5 45.9 37.6 43.1 43.0 21.1 41.6 TARDBP "ALS10, TDP-43" ENSG00000120948 "TAR DNA binding protein" Q13148 1 11012344-11030528 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003703, HPA017284" Supported Enhanced Nucleoplasm NA NA 29000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB003703: AB_425904, HPA017284: AB_1857775" "unprognostic (3.72e-3)" "prognostic favorable (1.15e-5)" "unprognostic (1.06e-1)" "unprognostic (1.22e-1)" "unprognostic (8.52e-2)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.20e-7)" "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (4.75e-3)" "unprognostic (2.24e-1)" "unprognostic (2.54e-2)" "unprognostic (2.27e-3)" "unprognostic (2.27e-1)" "unprognostic (1.87e-1)" "unprognostic (2.86e-1)" "unprognostic (2.71e-2)" 83.4 80.1 71.9 87.1 80.6 69.7 83.3 84.7 79.0 93.9 78.1 94.5 77.4 90.9 78.8 111.1 84.1 58.7 93.0 69.4 78.5 93.8 105.5 91.6 106.5 75.5 77.2 103.5 77.2 86.7 89.1 82.7 76.4 90.1 94.5 119.9 86.6 78.8 138.9 96.1 94.5 81.2 74.8 97.4 82.4 68.2 74.7 115.1 96.6 102.9 122.9 87.6 95.8 86.0 244.7 164.4 270.4 143.5 143.9 118.2 160.3 164.7 142.3 263.6 195.5 187.9 175.6 316.3 118.1 180.6 154.3 169.2 333.1 187.6 336.0 175.1 153.8 241.2 275.2 257.9 119.4 290.5 158.9 99.5 211.4 184.5 147.9 143.8 188.6 126.7 319.0 176.4 221.7 195.0 215.6 228.6 221.0 232.2 141.7 256.9 214.4 206.2 186.0 179.1 187.9 150.8 221.3 173.7 128.8 197.1 173.8 200.9 174.8 173.8 207.8 146.3 236.9 133.3 176.2 336.3 116.2 288.2 192.0 38.0 38.0 33.7 46.7 48.6 57.4 55.2 46.9 45.4 61.7 39.6 46.3 50.5 15.4 67.2 50.0 43.1 54.3 36.4 71.9 80.6 84.7 79.0 69.4 78.5 75.5 77.2 76.4 74.8 74.7 86.0 35.5 32.1 74.4 29.4 57.6 114.6 89.9 40.8 52.3 37.6 52.0 38.6 68.0 31.5 57.0 29.5 29.2 63.2 46.3 54.2 33.2 50.8 9.7 50.7 50.0 54.9 66.3 63.5 29.5 54.2 84.5 45.2 34.7 61.7 42.3 45.8 40.0 51.7 50.1 37.0 29.8 50.1 38.7 45.9 46.3 12.3 47.2 37.8 35.6 23.4 54.3 36.2 35.0 37.2 57.2 52.9 36.1 51.6 48.8 71.7 43.2 43.9 54.4 38.8 32.9 42.8 56.9 64.9 32.8 52.4 114.5 73.5 41.3 23.6 52.6 71.3 TBC1D7 "dJ257A7.3, FLJ32666" ENSG00000145979 "TBC1 domain family member 7" Q9P0N9 6 13266542-13328583 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "melanoma: 13.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 320.4;U-266/84: 174.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034748 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "HPA034748: AB_10671232" "unprognostic (9.53e-2)" "unprognostic (8.39e-2)" "unprognostic (3.18e-1)" "unprognostic (1.81e-2)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (3.95e-3)" "unprognostic (5.54e-2)" "unprognostic (9.30e-2)" "prognostic favorable (4.98e-5)" "unprognostic (4.36e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (2.03e-7)" "unprognostic (1.57e-1)" "unprognostic (3.46e-2)" "unprognostic (3.48e-1)" "unprognostic (2.78e-2)" 9.4 12.0 14.3 9.7 15.9 26.5 11.5 13.0 26.3 10.8 9.9 15.2 14.5 8.4 20.0 17.1 6.6 10.3 31.7 14.3 12.9 21.4 17.5 11.0 13.9 11.8 11.6 7.7 10.2 12.4 10.7 14.4 13.4 12.4 16.5 11.5 12.2 7.0 16.2 13.8 10.8 10.1 10.7 12.3 9.8 14.0 12.7 16.9 8.0 14.5 15.6 10.0 11.4 15.8 26.2 25.5 36.0 36.8 27.5 15.7 24.9 11.5 13.3 24.0 26.8 51.8 23.0 18.1 75.0 19.3 55.8 20.8 24.5 29.0 21.9 28.4 29.1 50.3 16.5 45.8 63.6 32.7 73.6 21.4 40.6 29.7 19.3 24.0 40.5 57.2 57.3 23.7 30.8 42.8 42.2 78.5 24.4 32.4 24.6 61.7 15.7 77.7 54.1 35.1 69.4 30.8 28.4 55.4 320.4 71.3 53.6 19.1 29.4 24.6 30.8 13.6 16.2 55.8 174.2 86.2 23.1 34.1 51.1 28.2 21.6 27.0 11.6 20.0 7.6 15.4 9.9 10.5 43.3 14.5 9.1 11.1 42.2 21.4 13.7 42.2 14.6 10.4 14.3 15.9 13.0 26.3 14.3 12.9 11.8 11.6 13.4 10.7 12.7 15.8 11.0 12.8 13.9 3.9 16.2 7.5 9.9 37.2 11.4 6.5 15.7 20.6 30.6 15.7 28.8 16.5 4.2 41.0 15.0 12.9 33.2 16.4 8.1 15.2 12.7 12.4 9.0 57.4 8.4 14.3 23.3 9.9 15.8 15.7 9.5 14.4 12.1 15.2 24.2 10.1 9.5 18.3 50.8 12.9 23.0 5.8 4.4 31.3 10.6 4.7 13.9 8.9 13.4 6.6 7.3 22.2 18.3 5.3 21.9 11.6 13.1 56.1 16.4 8.0 13.1 5.6 20.2 14.7 34.3 21.7 8.9 46.9 11.3 14.4 16.4 13.4 TBCB "CG22, CKAP1, CKAPI" ENSG00000105254 "Tubulin folding cofactor B" Q99426 19 36114289-36125947 "Metabolic proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Chaperone, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 448.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041428, HPA041722" Approved Supported Cytosol NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA041428: AB_10794517, HPA041722: AB_10804007" "unprognostic (3.88e-3)" "unprognostic (3.05e-1)" "unprognostic (8.52e-2)" "unprognostic (1.38e-2)" "unprognostic (7.94e-2)" "unprognostic (1.25e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.15e-2)" "unprognostic (5.19e-2)" "unprognostic (1.32e-1)" "prognostic favorable (3.11e-4)" "unprognostic (4.54e-2)" "unprognostic (6.34e-3)" "unprognostic (9.20e-2)" "unprognostic (6.11e-2)" "unprognostic (5.39e-2)" "unprognostic (1.02e-1)" 83.7 83.8 332.0 49.9 365.5 52.8 77.9 365.7 448.6 95.6 289.2 102.5 34.9 117.6 33.0 83.3 88.7 31.0 109.5 332.5 357.6 92.0 57.5 73.3 52.1 368.9 354.4 89.6 44.8 47.5 116.3 36.6 370.0 67.4 29.8 62.3 51.6 46.8 87.8 58.7 66.6 48.0 356.8 76.1 69.7 89.4 359.9 53.3 58.8 49.5 42.3 99.7 82.0 412.4 119.8 361.0 122.7 89.0 84.2 83.4 54.8 95.6 72.6 158.0 111.5 161.0 62.0 99.4 167.4 144.9 114.3 59.0 99.8 102.6 84.0 231.4 127.9 85.5 89.4 224.9 104.7 96.6 166.8 97.6 74.7 123.9 76.4 105.7 102.5 139.7 39.7 141.1 125.3 189.2 152.6 117.5 83.0 137.8 139.8 135.2 69.5 93.2 137.9 108.3 139.6 153.0 89.3 112.2 102.9 109.2 58.7 120.2 106.5 156.9 166.9 91.3 181.4 70.9 182.3 113.1 140.7 99.2 87.5 310.8 240.3 318.5 286.0 335.8 190.5 258.8 260.4 249.5 265.2 246.6 155.9 195.5 103.8 246.1 409.3 280.2 386.5 358.2 332.0 365.5 365.7 448.6 332.5 357.6 368.9 354.4 370.0 356.8 359.9 412.4 110.6 60.9 29.7 13.1 76.9 66.9 89.8 170.1 56.9 61.3 73.5 98.9 53.5 58.6 90.9 138.0 12.5 136.7 111.5 64.8 180.0 147.2 143.5 88.7 85.6 100.9 107.2 52.4 14.0 111.8 212.5 93.0 53.0 80.5 83.7 99.4 80.7 33.7 160.5 72.3 14.9 58.4 160.7 70.9 154.0 274.0 90.1 95.8 129.9 13.1 239.2 127.8 142.2 11.6 68.3 129.8 95.3 101.2 53.3 61.7 63.1 188.4 115.8 85.6 65.7 75.6 195.8 108.3 156.9 71.7 67.6 82.6 114.3 88.2 56.7 78.5 TBL3 "SAZD, UTP13" ENSG00000183751 "Transducin beta like 3" Q12788 16 1972053-1982929 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 113.8;Late spermatids: 72.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042562, HPA055695" Enhanced Supported Enhanced Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoli "HPA042562: AB_10964911, HPA055695: AB_2682888" "unprognostic (1.96e-1)" "unprognostic (5.49e-3)" "unprognostic (8.49e-2)" "unprognostic (1.56e-1)" "unprognostic (4.67e-1)" "unprognostic (2.65e-1)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (3.78e-2)" "unprognostic (8.03e-2)" "unprognostic (2.14e-2)" "unprognostic (8.32e-2)" "prognostic favorable (7.33e-4)" "unprognostic (3.65e-2)" "unprognostic (1.87e-1)" "unprognostic (2.32e-1)" "unprognostic (3.77e-1)" 3.6 3.5 1.8 3.2 2.2 2.1 3.9 4.5 2.7 3.4 1.0 3.4 2.4 3.8 0.6 4.9 3.0 1.4 4.7 2.3 2.3 3.3 3.1 2.8 2.3 3.3 2.0 3.7 5.9 2.8 2.4 1.2 3.4 2.8 1.0 1.5 4.8 1.1 10.6 5.4 3.5 1.4 1.7 3.0 3.7 6.8 1.8 2.0 3.1 3.1 1.5 3.3 3.5 2.7 7.1 13.4 3.6 7.2 3.5 2.8 11.8 6.4 4.2 5.4 4.4 17.3 13.3 9.4 14.6 4.9 4.9 18.8 5.9 7.5 2.8 6.9 8.5 5.9 7.1 6.6 4.0 10.3 5.4 2.8 5.5 6.7 3.9 4.3 6.8 5.6 12.1 6.7 3.2 11.3 13.2 5.8 8.6 6.2 5.4 23.1 6.7 15.7 2.6 2.7 8.4 6.5 5.8 14.6 6.0 3.5 11.1 6.9 10.8 7.4 8.8 6.6 12.6 12.1 5.6 15.0 4.5 6.5 8.7 4.5 9.4 5.5 10.6 11.0 9.3 6.4 7.6 10.4 10.4 6.9 9.7 7.4 2.2 14.5 11.8 5.3 9.2 8.5 1.8 2.2 4.5 2.7 2.3 2.3 3.3 2.0 3.4 1.7 1.8 2.7 9.1 3.2 12.2 2.3 11.9 13.0 15.8 21.9 12.0 13.0 12.6 10.4 16.4 7.2 16.4 18.4 8.4 26.4 10.7 23.4 7.9 25.4 113.8 7.4 8.5 11.2 13.8 18.5 2.0 22.5 26.0 10.5 20.4 9.7 14.7 14.5 7.1 12.7 19.6 10.1 2.1 16.1 18.3 8.9 6.6 72.1 14.9 8.5 7.2 0.0 24.1 13.6 9.2 2.0 2.0 24.0 22.0 10.9 13.5 15.6 31.9 16.9 8.8 9.8 26.3 11.1 24.7 21.8 20.8 13.7 18.3 22.4 11.1 11.6 24.2 14.4 TBPL2 "TBP2, TRF3" ENSG00000182521 "TATA-box binding protein like 2" Q6SJ96 14 55413541-55456726 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;skeletal muscle: 1.7" "Cell type enhanced" "Detected in some" "Microglial cells: 1.0;Smooth muscle cells: 2.0" "Cancer enriched" "Detected in single" 40 "testis cancer: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 5.7;HMC-1: 2.7;U-2 OS: 2.5;U-937: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056241 Uncertain NA NA "Cluster 45: Intestine - Brush border" "Cluster 44: HDLM-2 - Immune response" "Cluster 10: Non-specific - Unknown function" "HPA056241: AB_2683076" "unprognostic (3.42e-1)" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" "unprognostic (3.06e-4)" "unprognostic (1.43e-1)" "unprognostic (1.32e-1)" "unprognostic (1.76e-1)" 0.2 0.5 0.6 0.8 0.7 0.5 0.0 1.7 1.2 0.4 0.4 0.2 0.9 0.7 0.0 0.2 0.2 0.1 0.0 0.6 0.4 0.2 0.2 0.4 0.3 1.5 0.6 0.1 0.2 0.1 0.0 0.2 0.8 0.3 0.2 0.1 0.6 0.1 1.7 1.3 0.6 0.0 0.2 0.5 0.5 0.8 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.5 2.0 0.5 0.0 0.6 0.0 0.6 1.2 0.0 0.0 0.0 0.2 0.2 0.3 0.4 1.6 0.0 0.2 0.5 0.1 0.0 0.0 5.7 0.0 0.4 0.6 0.0 0.0 0.0 2.7 0.0 1.0 0.0 0.2 0.0 0.0 0.1 0.3 1.9 0.0 1.4 0.3 1.0 0.4 0.0 0.5 0.5 0.0 0.4 0.0 0.8 0.7 0.5 0.0 0.1 0.2 0.0 0.8 0.7 0.0 0.2 2.5 0.2 0.4 1.7 0.9 0.2 0.3 4.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.6 0.7 1.7 1.2 0.6 0.4 1.5 0.6 0.8 0.2 0.5 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.3 2.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 TBRG1 "FLJ14621, NIAM, TB-5" ENSG00000154144 "Transforming growth factor beta regulator 1" Q3YBR2 11 124622836-124635926 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 21.6;HMC-1: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055645, HPA068022" Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA055645: AB_2682873, HPA068022: AB_2685942" "unprognostic (1.64e-2)" "unprognostic (3.24e-2)" "unprognostic (7.81e-2)" "unprognostic (1.37e-2)" "unprognostic (9.21e-2)" "unprognostic (3.66e-1)" "unprognostic (1.03e-1)" "unprognostic (4.58e-2)" "unprognostic (1.18e-3)" "unprognostic (1.52e-1)" "unprognostic (7.40e-2)" "unprognostic (3.72e-3)" "unprognostic (1.78e-1)" "unprognostic (1.70e-1)" "unprognostic (1.22e-1)" "unprognostic (3.83e-1)" "unprognostic (7.13e-3)" 5.5 7.2 6.4 5.5 9.5 4.0 4.3 5.3 9.8 3.8 5.9 5.9 6.2 3.9 4.0 5.0 4.1 3.1 4.3 6.9 6.6 6.2 8.1 6.0 6.4 5.6 5.2 2.7 8.1 2.3 4.1 3.8 5.3 5.1 5.4 1.8 5.6 3.0 10.1 5.1 8.4 2.5 5.1 8.3 6.8 3.4 6.0 3.9 5.7 3.9 6.1 4.3 4.0 7.2 3.7 3.1 2.7 1.5 4.6 3.1 2.7 3.7 2.5 2.0 1.8 6.0 2.7 4.4 4.5 3.7 4.0 4.5 3.5 4.8 3.8 4.5 2.7 21.6 1.8 3.9 3.2 6.7 20.9 3.2 8.1 3.7 2.8 2.3 3.6 3.6 7.4 4.8 5.1 1.7 3.0 6.6 2.9 8.6 2.1 2.7 3.6 3.2 3.3 3.6 2.2 2.3 2.1 3.5 2.5 2.5 5.6 3.3 5.5 4.5 1.8 1.5 3.2 3.8 6.2 5.1 2.5 7.8 3.2 30.5 24.3 35.1 25.6 22.9 19.1 34.0 25.9 22.1 14.8 30.6 27.4 22.1 33.1 14.6 21.7 23.9 27.5 13.1 6.4 9.5 5.3 9.8 6.9 6.6 5.6 5.2 5.3 5.1 6.0 7.2 37.9 44.8 56.5 37.9 67.2 46.1 52.0 37.5 67.2 19.2 34.8 30.6 24.0 40.0 39.5 23.9 12.5 32.9 58.0 46.4 52.8 38.8 61.3 25.1 31.1 42.7 28.3 43.3 113.8 47.4 28.8 45.9 39.3 25.9 72.1 23.6 31.8 69.7 36.2 30.3 53.6 46.7 30.5 45.8 66.8 11.5 37.9 55.9 33.8 41.2 53.6 33.5 64.9 33.7 50.1 58.5 43.2 33.4 62.1 88.7 61.9 90.4 33.9 19.5 26.3 39.3 83.3 52.0 24.7 42.5 48.2 48.3 65.7 27.7 33.4 68.6 TCERG1 "CA150, TAF2S, Urn1" ENSG00000113649 "Transcription elongation regulator 1" O14776 5 146447311-146511961 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064854, HPA069752, HPA069808" Supported Enhanced Nucleoplasm NA NA 17000 "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA064854: AB_2685370, HPA069752: AB_2686190, HPA069808: AB_2686204" "unprognostic (2.73e-1)" "unprognostic (5.11e-2)" "unprognostic (1.27e-3)" "unprognostic (8.58e-2)" "unprognostic (1.32e-1)" "unprognostic (9.32e-2)" "prognostic unfavorable (5.34e-5)" "unprognostic (1.07e-1)" "unprognostic (3.38e-2)" "unprognostic (2.13e-2)" "unprognostic (2.41e-1)" "unprognostic (1.35e-3)" "prognostic unfavorable (4.70e-11)" "unprognostic (1.52e-2)" "unprognostic (7.76e-2)" "unprognostic (3.98e-2)" "unprognostic (1.24e-3)" 11.6 8.6 6.6 15.5 6.1 28.1 12.0 7.9 10.0 11.6 4.1 12.2 10.5 13.3 6.4 13.1 12.5 7.3 10.0 6.4 5.2 9.2 6.7 10.5 17.7 5.5 5.1 13.7 9.0 8.9 11.3 12.4 5.5 10.4 10.8 16.9 10.9 8.4 23.7 13.2 11.2 10.4 4.2 12.0 11.7 10.3 5.3 19.0 10.0 13.6 17.1 12.4 12.3 8.8 51.7 37.6 56.6 39.1 15.2 23.9 72.0 38.0 30.6 42.1 48.8 61.0 53.8 89.0 27.8 31.7 30.0 44.6 70.1 48.1 63.8 52.6 56.3 58.1 43.4 37.4 16.3 87.8 43.5 16.8 28.0 40.8 43.7 23.0 37.3 73.5 69.4 31.9 32.2 36.8 76.8 49.3 56.3 29.2 42.3 74.3 66.9 58.7 26.3 40.2 36.8 45.6 42.7 44.6 28.3 34.1 47.5 43.9 42.2 36.3 42.1 31.0 60.2 32.4 38.3 116.8 33.7 73.0 41.3 0.9 5.7 2.5 5.7 8.8 6.9 5.5 6.6 7.2 9.7 5.5 6.8 6.8 0.5 9.5 11.9 4.9 6.5 5.3 6.6 6.1 7.9 10.0 6.4 5.2 5.5 5.1 5.5 4.2 5.3 8.8 35.8 54.5 49.8 50.6 49.5 44.9 49.5 35.6 54.7 54.1 32.4 33.1 35.6 14.3 39.9 23.9 62.6 48.6 42.9 20.8 1.9 31.9 3.2 23.8 62.1 37.6 28.2 77.0 100.9 33.4 60.7 43.3 56.6 44.1 37.9 57.4 21.4 17.6 30.8 35.3 91.0 36.9 24.4 28.9 30.4 7.4 28.6 36.5 24.9 42.2 33.1 20.8 35.0 73.4 76.3 44.9 25.3 24.5 61.9 60.7 13.8 7.6 33.8 38.4 19.7 53.2 51.1 73.3 60.8 66.6 45.7 43.9 42.8 43.7 47.5 62.2 TCP1 "CCT1, Ccta, D6S230E" ENSG00000120438 "T-complex 1" P17987 6 159778498-159789703 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 586.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017460, HPA027337, HPA031082" Approved NA NA 2300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "CAB017460: AB_10618875, HPA027337: AB_10600774, HPA031082: AB_10600990" "prognostic unfavorable (8.88e-5)" "unprognostic (1.34e-2)" "unprognostic (1.64e-3)" "unprognostic (2.67e-2)" "unprognostic (5.50e-2)" "unprognostic (1.39e-3)" "prognostic unfavorable (1.49e-5)" "unprognostic (1.54e-2)" "unprognostic (2.44e-1)" "unprognostic (2.64e-2)" "unprognostic (9.34e-2)" "unprognostic (5.17e-2)" "unprognostic (2.10e-3)" "unprognostic (1.81e-1)" "unprognostic (2.15e-1)" "unprognostic (1.76e-1)" "unprognostic (1.54e-1)" 114.1 92.9 110.5 90.8 117.0 181.5 106.0 119.2 179.4 88.3 118.1 103.6 71.7 97.8 84.9 103.8 93.2 69.2 114.8 117.4 120.5 105.8 98.0 89.5 105.7 117.3 118.1 122.8 96.0 98.2 57.0 83.5 120.9 81.0 108.1 76.8 92.2 72.6 171.8 101.3 84.7 99.7 122.2 82.2 92.3 174.0 118.0 98.2 77.1 125.4 128.3 101.9 84.8 141.4 236.3 284.1 296.9 405.2 260.5 209.0 456.5 344.6 170.4 423.3 320.9 571.4 170.9 579.5 233.4 275.2 494.7 339.0 793.5 350.2 601.5 301.8 380.6 606.7 292.7 545.9 199.1 496.7 308.9 204.3 215.0 417.5 392.0 241.8 381.7 498.8 856.1 262.8 399.4 201.5 620.2 590.4 321.6 305.0 310.3 447.8 219.7 474.7 345.1 170.7 365.8 237.7 323.3 452.3 161.3 386.2 212.6 464.2 264.0 203.9 310.0 467.0 717.6 238.5 531.7 638.4 293.8 571.8 329.1 92.0 73.8 93.6 84.3 99.1 110.1 95.8 92.6 91.7 90.4 74.2 94.4 92.4 34.4 101.1 131.5 55.4 105.0 114.2 110.5 117.0 119.2 179.4 117.4 120.5 117.3 118.1 120.9 122.2 118.0 141.4 122.4 51.3 38.8 12.4 95.4 171.7 304.4 153.2 75.7 39.1 95.2 75.2 68.2 81.5 108.6 27.6 29.2 161.7 80.7 93.8 115.4 191.9 427.4 113.4 140.1 106.4 104.4 119.5 22.8 134.6 288.7 98.6 64.2 122.2 104.6 109.8 51.0 43.8 118.7 30.3 24.3 84.6 120.1 65.7 134.4 586.4 86.0 91.5 108.5 22.5 99.9 73.3 77.2 18.1 25.3 151.1 75.7 92.2 93.0 235.2 84.0 152.3 127.1 53.1 72.3 111.9 247.2 307.3 237.1 93.4 148.0 240.4 116.6 100.6 133.8 249.3 TECR "GPSN2, MRT14, SC2, TER" ENSG00000099797 "Trans-2,3-enoyl-CoA reductase" Q9NZ01 19 14517085-14565980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1013.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029780, HPA056488" Supported Supported "Endoplasmic reticulum" NA NA 10000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA029780: AB_10603348, HPA056488: AB_2683149" "unprognostic (9.73e-2)" "unprognostic (3.69e-3)" "unprognostic (1.55e-1)" "unprognostic (8.08e-3)" "unprognostic (1.20e-1)" "unprognostic (3.96e-2)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (9.16e-2)" "unprognostic (1.29e-1)" "unprognostic (5.05e-2)" "unprognostic (3.65e-3)" "unprognostic (2.53e-3)" "unprognostic (2.34e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.60e-4)" 102.7 162.6 189.0 43.1 201.7 74.2 100.4 220.8 237.5 156.8 216.5 78.5 106.1 53.2 103.2 373.2 87.1 49.7 78.4 180.1 200.0 112.2 133.9 67.8 55.7 209.6 191.2 80.9 105.5 306.1 78.7 68.0 212.2 85.7 59.3 82.8 222.3 83.5 366.3 263.5 95.9 36.7 207.6 75.4 81.7 182.7 199.9 65.8 92.7 209.6 85.3 51.6 185.9 230.2 220.5 162.1 149.5 169.6 214.7 97.2 156.9 62.8 175.2 196.3 242.9 225.3 246.2 113.8 127.4 134.2 152.4 328.8 158.1 254.3 84.0 192.3 165.9 193.7 225.4 254.6 129.7 139.5 143.7 144.9 201.8 174.3 96.1 98.4 93.7 169.2 128.9 391.5 104.0 289.3 170.1 248.3 155.6 556.1 227.6 154.4 96.1 521.1 275.1 115.8 183.2 113.0 103.1 278.4 139.6 77.2 151.3 274.4 55.2 160.5 66.8 141.0 212.6 118.4 119.8 122.7 163.8 212.6 162.2 55.6 72.7 52.5 137.8 106.4 148.8 100.1 180.1 159.1 124.2 99.1 207.1 164.5 32.7 183.7 83.9 137.1 290.1 170.9 189.0 201.7 220.8 237.5 180.1 200.0 209.6 191.2 212.2 207.6 199.9 230.2 60.4 73.7 71.1 47.7 87.6 169.5 227.5 297.9 125.7 90.8 161.1 155.6 52.9 120.1 221.5 165.5 123.0 509.5 88.1 159.2 56.7 166.2 443.9 102.2 40.1 64.7 100.0 80.1 15.3 225.1 525.5 81.8 89.7 64.2 36.1 90.1 73.2 143.1 188.0 112.7 19.2 144.0 199.4 113.8 99.3 1013.1 72.7 77.8 163.7 18.7 61.6 577.9 103.0 12.5 46.5 104.8 128.2 60.2 206.1 110.2 343.2 202.9 213.1 177.5 65.7 68.4 286.7 215.0 134.2 255.3 239.7 486.2 117.7 116.0 216.2 196.5 THOC2 "CXorf3, dJ506G2.1, MRX12, MRX35, THO2" ENSG00000125676 "THO complex 2" Q8NI27 X 123600561-123733056 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047921 Supported Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA047921: AB_10960388" "unprognostic (2.12e-2)" "unprognostic (5.64e-2)" "unprognostic (3.49e-1)" "unprognostic (3.74e-2)" "unprognostic (2.22e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (5.77e-5)" "unprognostic (1.43e-2)" "unprognostic (1.04e-2)" "unprognostic (2.24e-2)" "unprognostic (3.24e-1)" "unprognostic (6.29e-2)" "unprognostic (4.27e-3)" "unprognostic (6.43e-3)" "unprognostic (1.05e-1)" "unprognostic (1.06e-2)" "unprognostic (1.35e-1)" 22.8 26.1 26.2 22.7 28.2 25.1 26.3 29.0 43.8 28.6 33.3 28.5 23.0 27.1 38.1 26.3 26.6 19.6 21.0 25.9 28.1 22.5 26.0 27.3 32.7 27.9 26.8 32.1 27.8 23.9 21.8 23.4 28.8 26.8 22.8 34.9 22.4 19.2 23.5 29.6 28.1 22.6 26.3 30.8 24.1 15.1 28.0 38.2 26.0 17.7 27.4 24.6 25.8 30.5 59.6 48.6 61.1 66.1 44.0 42.0 32.8 39.6 38.9 42.8 56.9 34.3 59.4 60.5 44.3 43.6 41.2 44.1 74.6 29.6 72.3 58.1 67.5 84.8 69.1 46.8 40.8 99.5 58.0 83.5 36.1 49.1 56.2 37.3 40.2 90.6 129.3 53.5 43.9 62.6 86.0 96.3 34.0 79.7 47.5 86.3 38.2 50.0 67.6 66.4 46.9 41.5 111.0 30.2 39.3 48.6 30.3 60.0 41.8 38.4 19.8 55.2 67.8 37.1 58.0 51.7 34.3 86.8 43.2 9.8 8.3 9.2 11.1 10.9 12.9 10.7 12.1 12.1 7.9 11.5 13.1 12.6 4.7 11.0 12.2 13.3 10.2 7.9 26.2 28.2 29.0 43.8 25.9 28.1 27.9 26.8 28.8 26.3 28.0 30.5 65.8 137.8 151.4 68.2 81.2 83.4 67.7 69.3 80.8 67.5 45.3 45.3 53.6 20.0 89.0 64.4 158.4 42.3 69.5 65.9 11.7 55.0 5.7 54.9 102.4 68.4 67.5 88.5 64.8 50.9 36.4 68.2 46.9 70.8 80.4 90.4 59.6 37.9 38.9 53.8 72.7 55.9 46.8 44.6 58.1 9.0 93.2 61.9 30.2 75.9 82.4 41.2 69.0 96.5 119.9 47.3 36.3 91.4 66.4 76.2 55.1 28.9 77.5 108.9 124.9 81.0 98.1 69.0 35.8 55.7 77.0 43.6 76.2 84.2 57.9 73.8 THRAP3 "BCLAF2, TRAP150" ENSG00000054118 "Thyroid hormone receptor associated protein 3" Q9Y2W1 1 36224432-36305357 "Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012041, CAB017472, HPA063765" Supported Enhanced "Nuclear speckles" NA NA 59000 "Cluster 6: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "CAB017472: AB_2271759, HPA012041: AB_1857983, HPA063765: AB_2685117" "unprognostic (8.53e-2)" "unprognostic (1.68e-1)" "unprognostic (9.29e-2)" "unprognostic (2.11e-1)" "unprognostic (1.71e-2)" "unprognostic (4.70e-2)" "unprognostic (2.65e-3)" "unprognostic (1.67e-1)" "unprognostic (9.30e-2)" "unprognostic (1.16e-1)" "unprognostic (5.08e-2)" "unprognostic (4.82e-2)" "unprognostic (3.34e-2)" "prognostic favorable (5.36e-4)" "unprognostic (7.56e-2)" "unprognostic (7.52e-2)" "unprognostic (1.23e-1)" 41.9 40.6 24.0 45.9 24.7 44.6 43.7 28.5 26.3 36.6 31.2 40.2 33.9 39.5 34.9 40.6 39.3 29.6 47.2 24.3 26.2 32.3 45.8 37.4 57.1 25.6 24.6 45.3 35.6 52.0 30.0 40.1 26.7 50.4 38.7 40.9 38.8 31.3 115.3 38.2 35.1 42.1 24.1 48.0 37.8 34.3 25.0 63.1 46.0 64.0 60.8 37.1 36.2 28.1 100.7 63.9 110.1 94.9 88.0 69.7 90.9 104.6 107.4 107.2 109.8 74.7 91.5 187.5 38.5 113.8 73.8 89.1 125.2 106.9 131.3 97.4 70.1 157.7 94.3 85.6 94.6 157.2 102.5 105.7 65.7 107.1 86.7 75.2 118.4 107.5 127.8 93.5 77.6 57.8 180.4 92.7 130.5 64.2 50.4 163.6 133.4 99.4 77.0 125.4 69.6 83.9 117.5 77.0 92.7 108.7 73.1 69.3 122.4 89.2 100.4 82.5 111.6 56.7 80.7 162.4 82.2 109.2 92.7 85.8 36.9 64.7 51.5 43.9 46.0 53.6 43.9 46.5 42.4 61.0 46.4 43.1 80.8 51.2 48.6 46.7 40.7 47.3 24.0 24.7 28.5 26.3 24.3 26.2 25.6 24.6 26.7 24.1 25.0 28.1 101.0 115.4 101.7 32.3 136.1 56.7 94.5 126.9 78.0 98.0 76.4 65.5 113.7 75.8 106.2 47.8 31.3 150.7 151.9 64.3 97.8 155.7 9.7 92.1 114.7 96.2 72.4 114.9 65.6 104.1 147.2 98.3 58.6 106.0 92.9 120.5 80.7 78.8 101.6 87.5 63.2 70.1 89.5 77.1 71.7 12.0 80.2 89.9 72.9 53.4 155.5 129.4 196.7 47.7 53.4 111.5 61.9 83.5 119.7 125.2 51.6 76.0 87.6 93.2 92.1 114.6 116.5 145.9 118.4 89.6 68.5 144.1 129.0 141.0 87.1 86.4 TIPRL "dJ69E11.3, MGC3794, TIP41, TIPRL1" ENSG00000143155 "TOR signaling pathway regulator" O75663 1 168178962-168202109 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027995, HPA054282" Approved Supported Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "HPA027995: AB_10602900, HPA054282: AB_2682435" "unprognostic (3.18e-2)" "unprognostic (1.05e-1)" "unprognostic (5.05e-2)" "unprognostic (3.17e-1)" "unprognostic (3.80e-1)" "unprognostic (2.35e-3)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.82e-2)" "unprognostic (3.32e-2)" "unprognostic (1.12e-2)" "unprognostic (4.30e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.45e-8)" "unprognostic (3.23e-1)" "unprognostic (1.57e-1)" "unprognostic (5.55e-2)" "unprognostic (8.61e-2)" 16.3 14.9 15.5 19.6 16.3 33.8 21.0 15.0 20.1 17.7 12.8 22.2 19.0 23.2 16.8 20.1 14.3 16.8 23.7 16.8 17.0 17.8 22.5 14.9 22.2 14.0 13.4 17.4 15.9 27.4 13.6 17.5 14.4 18.4 22.0 14.7 12.0 17.3 24.4 16.3 18.5 22.7 13.4 16.3 15.4 18.2 15.1 30.1 17.4 23.0 19.9 18.7 13.6 15.7 69.4 31.0 45.9 41.6 36.7 53.1 27.5 50.5 53.0 54.6 48.4 48.3 50.1 49.0 68.2 48.7 40.1 81.8 34.5 49.3 52.6 47.2 36.4 47.3 29.2 22.9 64.5 94.7 62.0 43.2 62.8 47.4 62.7 36.0 58.1 75.4 69.0 66.3 47.7 25.4 84.9 49.0 37.0 96.7 54.2 41.1 47.0 66.4 49.7 33.9 29.6 66.1 39.3 54.6 102.2 51.6 59.9 96.3 53.4 45.6 52.4 43.6 69.7 72.2 80.5 108.1 29.8 61.4 53.4 71.6 26.7 36.8 22.0 32.1 22.1 27.3 25.7 23.8 31.6 27.6 22.8 22.4 34.5 29.6 33.9 23.4 36.0 28.2 15.5 16.3 15.0 20.1 16.8 17.0 14.0 13.4 14.4 13.4 15.1 15.7 52.1 25.6 20.4 9.4 39.7 48.2 42.1 70.4 50.1 27.3 31.3 36.2 46.3 22.8 40.7 22.0 16.7 44.2 49.0 37.1 29.4 68.5 53.4 36.0 50.1 43.4 24.0 32.6 41.6 88.9 62.8 47.3 24.5 30.8 40.0 35.2 36.0 33.5 65.1 52.2 37.9 33.9 44.7 26.6 41.1 15.4 37.6 42.6 30.2 19.7 61.0 43.9 51.5 22.1 21.3 69.7 27.7 38.0 37.1 43.3 35.9 77.2 36.1 20.8 26.3 35.4 51.1 151.5 51.6 56.0 41.8 29.0 48.0 84.5 38.5 37.5 TM6SF1 ENSG00000136404 "Transmembrane 6 superfamily member 1" Q9BZW5 15 83107572-83144854 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 47.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;granulocytes: 44.4;Hofbauer cells: 50.9;Kupffer cells: 37.8;Langerhans cells: 46.4;Macrophages: 45.9;Microglial cells: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 76.6;eosinophil: 195.8;neutrophil: 118.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 195.8" "Cell line enhanced" "Detected in some" "HEL: 23.2;HHSteC: 49.6;HUVEC TERT2: 27.7;JURKAT: 36.4;TIME: 68.3;U-698: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016051, HPA056857" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "HPA016051: AB_2203924, HPA056857: AB_2683259" "unprognostic (8.09e-2)" "unprognostic (1.31e-1)" "unprognostic (2.87e-2)" "unprognostic (4.67e-1)" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (6.46e-2)" "unprognostic (3.52e-3)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.80e-1)" "unprognostic (2.55e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.15e-2)" "unprognostic (4.65e-3)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" 6.5 3.9 5.4 5.2 6.0 5.3 4.6 7.7 8.8 3.3 6.3 2.6 2.0 2.8 2.1 3.1 2.8 3.7 9.6 5.2 5.6 1.9 2.3 10.7 5.7 6.8 6.0 1.7 1.2 1.8 0.9 7.8 6.6 2.1 2.6 2.8 2.9 1.3 47.3 1.8 2.6 3.9 6.9 6.2 2.1 3.6 5.4 2.2 10.4 21.8 3.0 3.8 1.5 7.6 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.3 5.6 0.0 0.2 0.0 0.3 0.1 1.0 0.0 0.3 0.0 3.7 0.0 0.0 0.0 0.3 23.2 0.0 0.0 49.6 1.6 0.1 0.2 0.0 0.0 0.1 0.3 27.7 36.4 0.9 0.0 0.4 0.0 0.0 3.0 0.6 0.0 0.0 0.0 4.2 0.0 0.1 0.4 1.2 0.3 0.2 0.0 1.9 0.5 0.0 14.9 68.3 0.6 0.9 0.1 0.3 2.1 0.0 17.0 0.1 3.4 0.1 76.6 31.7 195.8 5.0 13.4 0.0 0.3 0.5 0.8 18.9 0.9 0.1 0.8 118.1 5.0 6.4 2.6 0.0 11.8 5.4 6.0 7.7 8.8 5.2 5.6 6.8 6.0 6.6 6.9 5.4 7.6 30.5 0.0 6.0 2.9 0.9 2.4 0.1 0.4 0.6 1.6 0.5 1.8 1.2 1.5 0.8 0.0 0.0 0.3 7.5 0.0 0.0 0.2 13.1 0.6 0.2 16.7 0.0 4.4 18.7 2.0 0.4 1.5 0.0 0.3 44.4 0.0 7.9 0.1 50.9 0.0 22.4 0.0 0.0 37.8 46.4 7.4 0.9 45.9 3.6 46.9 19.4 0.5 16.5 2.0 1.9 0.4 0.0 0.0 0.7 0.1 0.0 0.0 1.4 1.3 0.0 1.4 0.6 13.1 7.5 0.1 1.7 0.3 4.2 0.1 0.0 0.1 TM9SF4 "dJ836N17.2, KIAA0255" ENSG00000101337 "Transmembrane 9 superfamily member 4" Q92544 20 32109714-32167258 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064099 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA064099: AB_2685190" "unprognostic (3.10e-2)" "unprognostic (9.03e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.37e-6)" "unprognostic (3.85e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.15e-4)" "unprognostic (1.37e-1)" "unprognostic (3.23e-3)" "unprognostic (1.91e-1)" "unprognostic (6.65e-2)" "unprognostic (7.68e-2)" "unprognostic (6.98e-3)" "unprognostic (7.66e-2)" "unprognostic (1.45e-1)" "unprognostic (1.04e-1)" "unprognostic (4.23e-2)" 23.4 21.1 16.7 23.4 16.9 16.3 22.6 14.8 19.5 26.5 20.7 32.1 29.6 25.0 30.4 30.3 34.8 22.1 24.4 17.6 17.9 26.6 33.7 24.4 18.9 15.3 15.8 28.7 30.5 52.6 17.0 39.6 16.3 28.0 37.2 17.7 30.7 26.8 23.3 32.0 29.0 31.8 14.0 23.6 29.8 18.0 18.9 21.0 24.7 24.3 24.2 27.9 22.9 16.2 59.0 41.1 46.1 53.2 88.7 71.9 59.1 47.8 71.9 65.6 63.7 122.2 71.1 41.0 88.2 78.2 102.4 94.8 52.4 101.9 56.4 23.5 29.4 94.4 34.6 93.1 78.3 45.9 52.0 76.2 76.3 49.7 79.6 80.3 59.1 48.3 60.4 74.5 51.8 62.5 46.5 36.4 41.2 71.2 50.0 43.9 65.1 51.4 57.2 41.3 39.0 45.7 88.6 57.7 51.4 61.0 72.4 52.0 48.5 119.2 36.7 63.7 59.1 74.9 65.9 38.2 94.4 149.6 54.6 24.0 48.4 9.9 20.0 50.5 24.8 16.5 17.7 22.9 41.8 13.1 19.4 16.4 11.7 18.8 67.8 13.7 19.1 34.6 16.7 16.9 14.8 19.5 17.6 17.9 15.3 15.8 16.3 14.0 18.9 16.2 16.4 25.6 25.2 33.0 16.2 7.0 17.4 27.1 17.6 12.2 15.7 16.1 16.0 14.3 36.5 9.2 16.7 29.4 11.9 25.2 1.9 19.0 53.5 18.0 25.2 18.4 13.9 12.4 31.2 18.5 21.7 20.4 23.4 24.9 8.2 19.3 16.8 26.2 24.0 8.4 37.1 31.7 20.3 19.1 10.5 57.5 16.8 22.5 7.2 24.4 25.2 14.0 10.3 28.6 34.8 19.8 25.7 10.9 23.1 22.1 29.8 14.0 32.8 12.3 6.6 19.9 25.8 26.5 9.7 21.8 11.4 37.6 16.8 23.4 27.5 21.9 TMCO6 "FLJ39769, PRO1580" ENSG00000113119 "Transmembrane and coiled-coil domains 6" Q96DC7 5 140639435-140645408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037473, HPA037474" Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 14: Monocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA037473: AB_10671049, HPA037474: AB_10671050" "unprognostic (1.03e-1)" "unprognostic (3.40e-1)" "unprognostic (3.95e-2)" "unprognostic (1.38e-2)" "unprognostic (6.10e-3)" "unprognostic (1.31e-2)" "unprognostic (1.65e-1)" "unprognostic (2.11e-1)" "unprognostic (4.89e-2)" "unprognostic (1.69e-1)" "unprognostic (2.75e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (7.21e-2)" "unprognostic (1.77e-1)" "unprognostic (1.96e-2)" "unprognostic (1.20e-2)" 6.6 10.5 5.7 3.9 5.7 2.9 6.6 5.5 5.8 6.1 5.5 4.9 2.9 4.8 3.4 7.2 6.9 2.9 3.1 5.5 5.8 6.7 13.3 3.6 4.6 6.0 5.9 7.1 6.6 4.0 4.9 5.6 5.9 4.8 2.5 0.7 9.8 2.9 3.6 5.2 4.8 3.0 6.3 7.2 5.2 10.4 5.9 7.7 5.3 2.6 4.0 5.4 5.6 7.0 3.9 7.5 5.0 7.4 4.9 5.2 18.1 3.0 3.4 3.8 4.1 11.6 7.2 15.6 7.8 2.3 4.4 7.7 4.2 8.8 2.0 5.5 13.7 11.9 3.7 8.3 6.5 6.7 4.4 8.6 2.3 4.6 7.7 2.9 8.9 12.6 5.1 5.0 4.7 7.5 15.3 15.5 5.7 9.2 11.3 13.1 10.3 15.5 4.6 3.5 8.6 3.7 8.6 16.6 8.0 3.4 13.6 7.9 4.2 0.1 3.7 1.4 1.3 8.4 5.7 7.4 2.4 10.7 4.6 11.6 6.5 5.7 5.2 9.1 5.7 7.8 6.9 5.1 6.9 6.1 9.5 3.9 12.7 4.4 10.3 1.9 8.2 4.1 5.7 5.7 5.5 5.8 5.5 5.8 6.0 5.9 5.9 6.3 5.9 7.0 4.0 6.4 2.0 1.3 7.5 1.9 7.3 3.4 6.8 5.2 4.6 4.3 0.6 5.7 2.4 11.0 6.2 7.7 4.2 3.9 0.0 3.8 4.1 2.2 4.0 6.3 7.3 10.3 3.8 2.4 7.4 4.6 6.6 2.5 0.0 4.6 10.0 9.7 4.8 0.0 3.3 5.0 4.1 5.1 2.7 1.5 4.1 4.1 1.8 9.4 6.6 3.3 16.5 1.0 3.9 4.5 5.2 4.9 7.3 7.4 6.2 2.4 6.2 4.3 6.6 3.9 3.4 19.2 15.8 10.3 2.3 6.3 8.2 7.7 7.7 6.9 TMEM147 "MGC1936, NIFIE14" ENSG00000105677 "Transmembrane protein 147" Q9BVK8 19 35545600-35547526 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "unprognostic (6.98e-2)" "unprognostic (1.29e-1)" "unprognostic (2.32e-1)" "unprognostic (7.20e-2)" "unprognostic (1.38e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (4.98e-6)" "unprognostic (1.33e-1)" "unprognostic (2.53e-1)" "unprognostic (7.34e-2)" "unprognostic (1.35e-1)" "unprognostic (9.26e-2)" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (4.00e-2)" "unprognostic (1.85e-1)" "unprognostic (2.70e-1)" 78.5 153.3 75.1 36.6 80.3 41.8 71.1 84.8 85.8 72.7 117.4 67.6 43.2 77.5 101.8 105.0 64.1 36.3 112.2 74.1 83.1 96.5 63.8 68.2 29.9 80.8 79.0 69.1 149.6 129.5 76.1 46.1 79.6 54.8 54.0 42.0 80.6 58.1 137.7 118.9 52.3 57.5 80.9 58.6 84.0 76.3 80.3 26.7 99.7 85.8 45.1 77.2 73.5 85.2 161.2 353.2 68.9 162.0 298.4 135.8 110.5 94.3 167.2 124.6 115.2 168.6 96.9 93.3 156.8 156.4 135.1 62.8 119.9 147.4 101.7 140.8 156.3 99.3 98.9 200.3 237.2 145.4 105.6 148.8 226.3 117.5 291.5 107.2 115.6 126.8 127.9 325.2 134.1 201.6 82.4 80.8 96.9 492.8 141.3 79.1 62.3 225.4 198.5 164.6 60.5 101.0 93.7 215.3 204.9 69.2 78.2 121.4 73.8 140.5 109.9 81.0 205.0 165.9 182.2 52.8 122.3 195.7 115.6 41.0 219.7 103.3 100.6 212.6 142.6 177.0 135.9 116.3 199.9 149.0 101.0 102.6 12.2 106.1 154.0 237.5 147.1 237.4 75.1 80.3 84.8 85.8 74.1 83.1 80.8 79.0 79.6 80.9 80.3 85.2 74.4 44.8 44.1 7.2 71.5 101.2 135.7 195.5 63.2 55.3 167.2 165.1 101.5 118.7 110.2 156.3 18.8 176.3 63.2 59.6 111.6 223.0 102.5 56.4 72.5 96.8 88.9 42.5 6.0 255.2 228.7 94.7 51.0 68.1 50.2 90.9 82.8 95.5 260.6 45.4 8.0 105.9 140.4 133.6 113.3 333.8 139.4 96.5 240.1 7.5 83.7 138.9 71.1 10.1 12.2 179.9 74.1 121.1 136.0 349.1 100.3 277.1 77.9 62.8 118.3 58.1 138.9 327.9 155.7 94.9 167.8 138.3 60.6 86.1 144.3 200.6 TMEM192 FLJ38482 ENSG00000170088 "Transmembrane protein 192" Q8IY95 4 165070608-165208549 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014717, HPA024110" Enhanced Supported Nucleoplasm,Endosomes,Lysosomes NA NA "Cluster 37: B-cells - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Endosomes, Lysosomes" Nucleoplasm "HPA014717: AB_1844373, HPA024110: AB_2204898" "prognostic unfavorable (9.52e-4)" "unprognostic (5.38e-3)" "unprognostic (9.16e-2)" "unprognostic (4.39e-2)" "unprognostic (2.60e-2)" "unprognostic (1.55e-2)" "unprognostic (2.91e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (3.10e-1)" "unprognostic (3.27e-2)" "unprognostic (5.06e-2)" "prognostic favorable (2.33e-14)" "unprognostic (2.09e-2)" "unprognostic (1.37e-1)" "unprognostic (2.76e-2)" "unprognostic (9.30e-2)" 12.0 15.2 4.9 7.2 5.9 6.6 13.2 7.5 7.0 9.9 7.1 11.5 9.7 10.5 9.0 8.8 11.2 10.3 12.6 4.8 5.2 48.3 45.2 10.6 8.9 4.7 5.5 24.5 22.3 24.6 5.1 10.8 5.0 22.1 13.3 10.7 14.5 8.4 15.0 5.4 9.3 8.6 4.6 9.1 10.5 9.8 4.8 6.6 26.8 17.0 7.7 8.5 5.4 6.2 13.5 19.9 7.1 18.0 18.1 6.4 16.5 20.1 29.4 20.5 22.8 11.7 21.6 29.5 11.7 13.0 33.4 11.8 26.8 20.6 23.6 19.2 13.8 16.4 14.1 13.4 46.1 41.0 21.2 23.3 42.8 18.4 37.4 17.8 17.0 15.6 28.4 48.1 25.4 29.4 7.1 12.0 14.8 28.1 16.9 16.0 6.2 27.1 16.4 19.6 15.2 15.9 31.4 49.1 31.9 10.4 23.9 18.5 12.6 9.0 11.1 28.6 23.0 46.9 67.0 40.8 21.6 22.2 36.6 2.9 16.6 4.8 12.1 14.9 16.3 26.7 9.4 12.6 15.7 20.2 10.4 12.6 1.7 18.7 8.3 16.3 8.5 10.7 4.9 5.9 7.5 7.0 4.8 5.2 4.7 5.5 5.0 4.6 4.8 6.2 12.3 32.1 36.2 18.9 24.0 9.7 18.4 10.5 10.2 33.0 21.5 15.7 35.0 42.9 19.1 55.2 16.7 31.4 15.4 17.0 11.7 21.0 26.4 11.2 17.0 19.0 21.7 10.1 16.4 25.8 20.5 18.9 7.7 15.5 40.4 26.1 27.8 77.7 38.2 37.0 16.5 18.2 6.1 27.4 17.7 11.1 39.7 22.3 28.4 11.2 21.3 35.8 28.8 14.6 20.9 11.5 14.3 33.4 11.8 33.7 26.3 63.4 10.9 27.1 6.6 30.7 20.7 17.8 18.3 12.0 12.9 33.7 15.9 27.1 24.0 14.2 TMEM203 "HBEBP1, MGC14327" ENSG00000187713 "Transmembrane protein 203" Q969S6 9 137204082-137205648 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.31e-1)" "unprognostic (2.65e-2)" "unprognostic (4.53e-2)" "unprognostic (8.72e-2)" "unprognostic (1.10e-1)" "unprognostic (6.54e-2)" "unprognostic (2.72e-2)" "unprognostic (1.78e-1)" "unprognostic (1.43e-1)" "unprognostic (7.16e-2)" "prognostic favorable (4.78e-6)" "unprognostic (2.94e-1)" "prognostic favorable (1.50e-5)" "unprognostic (3.50e-3)" "unprognostic (1.57e-1)" "unprognostic (4.04e-2)" "unprognostic (1.19e-1)" 25.7 32.6 32.8 17.2 33.6 10.9 25.5 33.8 36.8 28.1 33.1 30.2 22.2 29.9 26.4 31.4 24.2 16.4 45.9 32.9 33.4 33.2 49.2 20.5 27.0 33.6 33.6 27.7 26.2 30.7 25.6 15.9 33.4 27.1 18.2 16.4 26.8 21.8 49.7 43.6 28.5 16.9 32.8 30.4 30.1 19.1 34.9 20.3 25.1 45.9 22.7 27.8 27.6 33.0 38.0 39.3 36.5 60.7 53.1 41.1 43.6 48.4 46.6 55.1 41.1 32.6 33.3 39.0 45.7 42.2 53.0 72.6 45.3 48.1 32.1 71.0 43.5 27.0 45.5 37.4 44.3 63.1 26.8 39.6 75.4 36.0 47.4 36.8 35.8 50.5 64.2 44.4 43.2 65.2 50.5 54.6 60.8 72.4 63.2 54.2 51.1 78.2 46.5 27.2 48.3 47.3 38.6 48.8 39.2 25.0 68.8 50.6 32.0 56.3 30.1 63.6 55.1 23.8 80.0 49.5 43.5 46.3 47.3 4.7 3.8 4.1 5.2 4.3 6.4 8.3 5.8 6.5 4.6 4.5 8.7 6.0 1.9 7.5 3.9 4.8 4.0 2.6 32.8 33.6 33.8 36.8 32.9 33.4 33.6 33.6 33.4 32.8 34.9 33.0 23.2 9.6 6.8 4.6 21.4 17.6 22.7 7.0 23.9 33.6 29.6 33.8 13.5 40.0 7.9 31.3 4.2 30.5 23.7 15.9 52.8 49.4 3.5 15.3 24.2 20.7 16.3 29.8 5.7 42.0 26.3 22.3 14.8 13.3 5.7 31.7 21.4 41.1 29.3 32.0 6.2 13.4 10.2 27.1 13.2 9.4 22.1 20.8 24.9 5.6 54.2 58.8 24.7 2.5 6.1 41.7 10.8 20.7 13.3 37.2 18.5 59.2 4.9 25.7 13.1 19.5 32.5 18.6 15.9 28.5 27.3 19.4 24.4 36.2 18.6 17.9 TMEM33 "FLJ10525, Pom33" ENSG00000109133 "Transmembrane protein 33" P57088 4 41935129-41960803 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075863 Approved NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA075863: " "unprognostic (7.14e-2)" "unprognostic (9.25e-3)" "unprognostic (1.59e-2)" "unprognostic (1.58e-1)" "unprognostic (1.92e-1)" "unprognostic (2.49e-1)" "unprognostic (2.04e-1)" "unprognostic (3.94e-2)" "unprognostic (5.45e-2)" "unprognostic (2.09e-1)" "unprognostic (1.16e-2)" "unprognostic (3.75e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.70e-2)" "unprognostic (4.20e-1)" "unprognostic (9.35e-3)" "unprognostic (2.36e-2)" 12.4 16.1 8.0 19.4 10.5 14.9 16.0 13.1 11.4 11.4 16.0 18.7 21.1 11.1 25.5 21.2 12.3 17.2 10.5 9.6 12.8 24.2 39.9 15.1 17.0 15.5 13.5 10.5 18.2 30.1 11.0 20.0 14.7 17.2 21.3 13.0 17.9 11.8 8.4 11.9 16.9 11.3 14.1 13.9 19.1 9.9 12.1 14.9 23.8 12.4 20.1 21.8 10.8 18.8 36.9 42.4 36.7 51.3 46.7 31.8 44.9 49.5 53.9 41.5 47.5 52.4 123.4 64.8 74.7 41.5 85.5 57.4 124.4 65.0 56.1 17.1 26.2 80.7 49.7 45.9 54.4 108.7 67.6 33.4 69.0 52.5 78.3 26.5 32.7 37.3 86.8 24.7 57.4 32.6 96.5 67.9 67.2 58.1 50.0 42.7 57.8 51.6 58.2 53.5 40.8 58.4 40.5 38.0 62.4 35.3 42.9 37.4 53.0 48.3 65.0 48.9 89.5 44.5 76.9 77.4 51.7 88.4 71.2 41.2 32.1 21.7 14.9 31.0 17.6 13.0 15.3 14.2 22.9 12.0 13.6 15.0 43.2 16.5 35.2 17.9 19.0 16.4 8.0 10.5 13.1 11.4 9.6 12.8 15.5 13.5 14.7 14.1 12.1 18.8 25.1 60.9 34.3 20.9 25.0 73.3 35.7 42.4 24.5 19.2 36.9 16.4 18.0 27.1 40.5 55.2 16.7 56.3 35.2 58.9 23.5 44.6 2.9 26.9 31.2 25.9 35.0 25.0 33.6 38.1 49.3 30.5 36.2 33.4 38.7 23.1 24.7 84.4 57.3 28.6 32.8 40.4 34.6 67.5 51.0 4.7 20.2 55.7 56.9 11.2 55.9 33.9 16.5 32.6 40.3 54.1 47.4 23.3 32.5 73.7 41.6 41.1 29.7 20.4 26.3 26.5 55.6 31.0 28.7 47.5 66.9 133.1 28.3 39.7 43.0 64.5 TMEM39B FLJ10315 ENSG00000121775 "Transmembrane protein 39B" Q9GZU3 1 32072031-32102866 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040191, HPA040224" Approved Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA040191: AB_10805706, HPA040224: AB_10795274" "unprognostic (1.74e-2)" "unprognostic (2.20e-2)" "unprognostic (4.38e-2)" "prognostic unfavorable (3.00e-4)" "unprognostic (1.06e-1)" "unprognostic (1.14e-2)" "prognostic unfavorable (2.82e-6)" "unprognostic (1.10e-2)" "unprognostic (3.37e-2)" "unprognostic (1.74e-1)" "unprognostic (3.63e-2)" "unprognostic (4.47e-2)" "prognostic unfavorable (5.11e-9)" "unprognostic (2.20e-1)" "unprognostic (5.80e-2)" "unprognostic (4.45e-2)" "unprognostic (2.10e-1)" 6.3 4.5 0.8 3.7 0.6 3.8 5.5 0.4 2.6 7.9 0.2 5.8 3.3 8.9 5.5 4.5 5.7 4.4 4.3 0.8 1.1 3.9 5.1 4.7 5.8 1.0 0.8 7.2 3.5 3.6 5.1 5.0 1.0 4.6 3.5 0.6 4.4 5.6 5.2 6.2 4.6 5.8 0.6 5.1 4.5 2.5 1.1 8.4 5.0 3.4 5.4 6.4 5.6 0.8 11.4 3.4 4.6 11.7 13.3 7.7 6.3 9.1 15.7 12.2 11.8 6.9 16.6 13.7 15.5 7.7 7.7 13.1 3.4 14.6 4.0 7.0 10.9 8.2 7.9 3.6 14.8 14.1 9.0 10.7 5.9 18.3 12.7 7.0 8.7 7.9 11.5 11.5 10.4 7.5 11.1 3.9 14.6 13.1 8.7 18.0 15.1 17.0 5.8 6.9 10.6 6.3 12.9 7.7 11.4 2.0 6.2 6.7 10.5 20.5 13.3 7.3 12.0 6.1 7.8 13.0 12.4 12.7 15.4 3.7 22.1 8.4 7.8 18.9 10.6 17.7 11.8 9.7 22.8 16.1 15.2 12.6 6.2 7.7 15.0 33.9 13.8 13.9 0.8 0.6 0.4 2.6 0.8 1.1 1.0 0.8 1.0 0.6 1.1 0.8 12.3 9.6 1.1 4.9 15.3 11.1 14.6 16.2 19.4 8.4 9.7 10.3 2.7 10.0 9.2 3.7 18.8 33.4 17.6 4.7 1.9 8.3 6.7 4.9 10.9 22.0 5.4 6.5 15.8 16.0 22.0 14.1 5.1 7.0 15.2 9.8 14.6 7.0 15.5 6.7 12.3 8.2 12.2 13.5 13.9 2.2 12.2 13.7 10.6 8.4 16.9 4.9 4.1 7.1 12.2 6.3 3.4 13.9 11.4 7.1 6.0 4.4 4.6 5.8 6.6 10.8 17.0 17.4 22.2 14.7 10.2 40.8 8.5 12.6 9.6 7.5 TMEM60 "C7orf35, DC32" ENSG00000135211 "Transmembrane protein 60" Q9H2L4 7 77793728-77798434 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062625 Approved NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "HPA062625: AB_2684811" "prognostic favorable (3.09e-4)" "unprognostic (1.06e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (1.02e-3)" "unprognostic (3.91e-2)" "unprognostic (5.28e-3)" "unprognostic (2.73e-3)" "unprognostic (3.46e-1)" "unprognostic (4.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (1.21e-2)" "unprognostic (2.72e-2)" "unprognostic (9.44e-2)" "unprognostic (2.07e-3)" "unprognostic (4.43e-3)" 15.9 23.9 17.5 17.6 17.4 10.6 29.6 18.4 21.4 21.7 19.5 24.9 17.7 16.6 29.7 15.3 18.9 18.6 17.1 17.4 19.3 30.4 35.5 18.9 29.2 18.0 17.5 23.3 18.2 39.8 17.5 23.5 18.2 17.4 24.3 14.1 21.2 19.9 22.9 16.5 17.0 19.6 18.9 20.4 16.4 24.1 17.8 20.4 25.8 20.3 27.7 16.9 13.1 19.1 45.7 30.3 46.2 54.4 61.6 54.5 21.2 41.8 79.9 44.2 69.9 28.4 56.8 35.1 10.0 39.4 150.6 46.8 44.0 24.6 49.7 27.5 41.9 19.0 26.9 39.9 43.4 26.9 33.9 39.9 35.1 32.8 39.6 42.8 31.9 32.0 45.7 68.2 70.4 49.3 20.4 68.7 32.3 55.3 39.4 24.1 36.6 50.7 52.9 33.9 23.2 37.4 31.4 43.7 66.0 48.7 52.8 49.0 21.2 55.6 38.7 49.2 31.4 27.6 46.6 51.1 42.3 55.8 50.2 208.6 51.3 100.2 29.2 58.7 32.4 88.9 51.0 36.9 40.3 72.5 42.9 36.6 52.7 32.3 54.7 52.6 79.4 41.2 17.5 17.4 18.4 21.4 17.4 19.3 18.0 17.5 18.2 18.9 17.8 19.1 16.5 9.6 11.5 2.9 33.5 30.0 34.6 61.7 25.6 7.6 37.5 42.4 8.0 20.0 29.0 44.1 8.4 56.4 17.6 22.0 52.8 28.4 9.4 17.7 13.7 20.1 9.1 14.5 6.1 29.8 40.2 26.9 11.7 14.5 24.7 21.1 24.7 26.3 70.8 13.5 6.5 30.6 61.1 43.5 38.9 10.9 45.7 39.1 28.4 7.5 42.6 21.5 21.6 3.0 7.9 27.6 31.4 35.3 15.4 35.4 30.3 50.5 31.4 12.4 52.6 12.6 50.5 49.8 40.3 31.0 33.4 43.9 20.8 16.4 23.6 39.3 TOP3B ENSG00000100038 "DNA topoisomerase III beta" O95985 22 21957025-21982813 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 112.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072114 Approved Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA072114: " "unprognostic (1.03e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (3.37e-1)" "unprognostic (5.04e-2)" "unprognostic (2.27e-1)" "unprognostic (3.93e-1)" "unprognostic (2.15e-2)" "unprognostic (2.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-2)" "unprognostic (1.96e-2)" "unprognostic (1.69e-2)" "unprognostic (1.21e-1)" "unprognostic (3.53e-2)" "unprognostic (1.11e-4)" 10.6 12.0 5.5 10.1 6.9 16.2 11.2 7.5 8.3 17.9 12.2 13.7 11.1 13.5 7.1 14.8 13.5 7.4 11.8 6.0 5.7 13.9 17.0 13.7 12.7 5.9 5.0 20.3 12.7 7.4 12.9 8.4 6.1 16.7 9.9 6.9 13.9 6.8 10.4 14.7 17.7 9.7 4.0 25.0 13.5 11.1 6.3 13.6 14.3 5.7 13.4 11.4 15.5 8.1 22.1 21.1 40.9 16.8 14.8 12.3 25.7 14.2 17.6 32.1 28.3 22.2 9.3 29.9 10.5 14.9 13.4 39.6 18.6 25.2 25.9 15.3 45.4 23.5 31.4 24.1 20.1 32.3 14.9 6.1 37.5 26.8 12.7 18.6 27.1 17.2 112.5 15.7 15.2 22.3 20.6 25.0 17.0 15.8 19.9 31.6 27.1 4.6 15.8 28.9 26.7 19.3 17.4 15.4 13.7 16.4 11.9 20.7 19.9 13.2 27.6 13.0 17.6 23.2 20.8 28.2 10.2 19.4 14.0 1.9 4.3 1.8 5.5 4.4 3.8 4.5 3.6 3.9 4.7 4.9 3.3 3.5 1.5 4.3 2.6 5.4 4.2 3.7 5.5 6.9 7.5 8.3 6.0 5.7 5.9 5.0 6.1 4.0 6.3 8.1 7.2 0.0 2.6 12.1 7.2 1.8 2.6 6.2 2.8 4.6 3.7 3.9 0.2 8.6 5.0 3.7 10.4 5.2 7.2 7.0 1.9 4.8 1.3 5.3 6.7 5.7 4.8 2.1 8.9 4.3 3.6 4.3 12.2 5.0 1.3 15.0 7.9 7.1 4.0 1.7 7.7 5.3 4.1 3.4 3.8 1.8 10.5 5.1 5.4 6.5 4.3 3.1 5.2 4.5 9.2 6.4 4.6 7.5 6.1 3.4 4.5 2.8 8.2 6.1 6.6 4.9 9.6 6.6 4.9 3.6 1.6 4.0 5.9 7.6 5.8 2.9 TPD52L2 "D54, hD54, TPD54" ENSG00000101150 "TPD52 like 2" O43399 20 63865228-63891545 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 187.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047489 Approved Approved Vesicles,Cytosol NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Vesicles Cytosol "HPA047489: AB_2680067" "unprognostic (1.17e-2)" "unprognostic (2.43e-1)" "unprognostic (3.25e-2)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.39e-5)" "unprognostic (3.63e-3)" "unprognostic (9.95e-2)" "unprognostic (1.17e-2)" "unprognostic (1.47e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (1.74e-8)" "unprognostic (2.79e-1)" "unprognostic (7.07e-2)" "unprognostic (3.33e-2)" "unprognostic (3.15e-3)" 85.1 84.6 75.8 52.8 76.8 98.9 68.9 76.0 88.1 74.1 74.0 79.7 38.3 72.6 31.4 109.6 68.0 42.6 85.7 76.8 81.6 66.2 51.4 60.8 43.2 80.8 77.4 60.7 45.5 38.3 58.9 65.9 79.5 66.3 35.2 24.6 50.3 60.9 70.2 70.8 52.6 72.1 78.0 71.4 54.5 40.2 83.5 35.7 49.8 53.4 41.7 83.6 71.5 81.4 175.2 87.9 54.5 66.9 122.4 193.8 80.4 196.7 173.0 343.1 145.0 326.9 194.9 70.0 211.3 200.0 204.2 168.4 111.5 269.0 198.7 39.5 46.4 66.9 112.6 199.6 129.9 85.0 66.3 140.3 296.6 138.5 221.3 121.6 160.1 74.0 140.4 101.0 137.0 96.3 83.5 109.4 78.7 172.6 308.1 114.0 59.5 113.3 135.8 76.0 82.3 92.2 230.9 177.5 165.3 80.3 120.6 171.5 170.1 273.4 79.1 160.9 145.4 63.2 108.6 85.0 256.8 79.0 86.6 66.9 73.0 47.1 29.4 55.1 36.8 33.5 32.3 34.2 47.6 31.4 32.4 29.8 137.3 47.5 48.1 24.0 38.8 74.6 75.8 76.8 76.0 88.1 76.8 81.6 80.8 77.4 79.5 78.0 83.5 81.4 37.5 16.0 23.4 36.2 26.6 44.1 28.3 58.8 33.0 18.9 28.0 31.1 45.4 20.0 31.3 22.0 6.2 77.2 28.6 27.8 39.2 50.5 7.8 21.7 38.4 36.7 18.6 26.9 19.6 32.1 104.0 37.7 23.9 31.9 38.7 25.8 28.9 14.5 187.3 8.4 21.7 27.2 20.3 47.4 33.0 12.1 42.0 52.3 28.4 7.5 50.6 32.5 27.8 13.6 32.3 74.8 25.1 65.1 29.4 51.7 37.5 36.6 26.5 19.7 46.0 18.9 65.6 13.9 25.6 37.2 42.3 108.8 25.0 42.3 27.9 44.4 TRAPPC3 BET3 ENSG00000054116 "Trafficking protein particle complex 3" O43617 1 36136570-36156053 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028408 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Cytosol "Golgi apparatus" "HPA028408: AB_10601826" "unprognostic (3.54e-3)" "unprognostic (1.17e-1)" "unprognostic (1.36e-1)" "unprognostic (4.94e-2)" "unprognostic (2.88e-1)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.70e-6)" "unprognostic (7.39e-3)" "unprognostic (1.15e-1)" "unprognostic (7.12e-3)" "unprognostic (7.38e-2)" "unprognostic (2.94e-1)" "unprognostic (9.25e-3)" "unprognostic (2.61e-2)" "unprognostic (9.47e-2)" "unprognostic (2.10e-3)" "unprognostic (6.53e-2)" 43.7 74.7 42.5 31.2 43.0 28.8 46.6 47.0 50.7 38.5 53.7 57.0 33.6 41.1 60.7 61.6 37.0 32.6 51.1 43.1 44.9 55.3 51.2 36.4 38.3 48.0 45.1 28.2 46.0 54.4 47.0 37.8 47.2 39.2 42.5 39.9 46.4 45.4 48.9 51.5 38.5 49.9 48.3 41.6 48.2 53.1 46.3 51.3 59.9 44.6 54.4 46.2 41.2 48.9 95.7 65.6 44.9 70.2 114.2 91.4 87.9 85.2 109.0 100.0 97.0 55.9 90.0 40.4 79.0 95.0 79.6 68.8 69.9 114.1 113.8 79.8 103.7 75.8 77.2 81.7 132.6 80.0 76.7 78.3 98.5 93.8 91.5 103.6 126.7 101.2 93.2 67.0 122.0 71.4 95.6 74.6 60.5 79.5 93.7 65.8 63.8 90.9 128.4 76.1 67.8 49.7 69.2 78.5 140.1 115.2 50.2 59.6 95.6 59.1 66.7 116.0 116.3 80.1 87.0 67.3 100.7 88.7 60.5 161.9 130.2 148.7 85.0 142.5 89.4 93.6 100.4 90.4 132.6 89.0 96.0 86.9 134.3 95.8 116.3 109.4 135.4 155.3 42.5 43.0 47.0 50.7 43.1 44.9 48.0 45.1 47.2 48.3 46.3 48.9 41.9 25.6 27.6 12.1 45.6 101.1 111.5 152.1 52.3 41.8 97.8 78.5 57.8 55.8 75.7 38.6 16.7 145.7 43.0 55.1 170.2 157.0 286.1 51.8 38.3 59.1 48.3 63.3 15.4 188.5 146.0 52.1 29.0 55.6 45.7 40.5 33.2 49.8 145.0 53.8 16.9 51.2 132.2 56.1 74.7 131.0 42.9 60.6 96.0 10.3 104.4 68.0 61.8 8.5 17.9 178.4 72.1 51.9 80.7 196.9 73.3 115.9 49.2 30.7 32.9 37.4 69.2 172.5 89.4 63.4 123.6 191.4 50.4 50.3 54.3 134.1 TRIP6 "MGC10556, MGC10558, MGC29959, MGC3837, MGC4423, OIP1, ZRP-1" ENSG00000087077 "Thyroid hormone receptor interactor 6" Q15654 7 100867387-100873454 "Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046454, CAB046460, HPA052813" Approved Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 21000 "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Focal adhesion sites, Cytosol" "CAB046454: AB_10604048, CAB046460: AB_2303907, HPA052813: AB_2681961" "unprognostic (7.94e-3)" "unprognostic (1.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.84e-3)" "unprognostic (3.52e-2)" "unprognostic (2.92e-2)" "unprognostic (3.18e-2)" "unprognostic (4.61e-3)" "unprognostic (8.48e-2)" "unprognostic (4.18e-2)" "unprognostic (5.08e-2)" "unprognostic (1.42e-1)" "unprognostic (1.25e-2)" "unprognostic (5.07e-2)" "unprognostic (9.71e-2)" "unprognostic (1.92e-1)" "unprognostic (1.25e-1)" 42.2 43.0 34.3 15.7 39.5 15.7 42.6 36.2 41.6 59.4 40.4 45.2 9.7 74.6 16.2 63.7 49.5 37.0 39.1 32.6 36.2 55.8 41.1 33.8 14.6 40.6 36.9 50.6 39.8 46.4 16.8 27.4 35.9 42.9 8.4 5.4 46.8 56.7 10.2 55.1 21.5 27.5 36.9 20.0 27.6 18.4 38.4 16.6 50.5 5.8 12.1 47.2 52.5 37.0 128.1 63.4 26.8 126.1 37.8 44.9 131.2 82.3 79.8 101.2 94.8 55.8 143.9 5.5 81.3 87.7 128.3 94.2 38.0 149.2 27.3 19.1 58.5 0.5 117.9 0.8 99.3 66.5 7.1 81.1 94.0 67.8 108.2 64.2 52.8 19.1 83.3 1.0 90.5 286.9 1.3 99.5 92.4 52.3 50.4 47.9 27.0 12.7 65.5 42.8 9.7 1.7 67.5 192.3 78.1 43.8 20.3 77.5 86.5 149.5 145.8 167.5 186.7 1.0 2.1 0.8 92.9 7.8 230.5 0.0 1.2 0.2 0.1 2.1 0.4 2.5 0.9 0.7 1.9 2.4 1.1 0.6 0.0 0.0 3.8 5.2 0.9 0.4 34.3 39.5 36.2 41.6 32.6 36.2 40.6 36.9 35.9 36.9 38.4 37.0 24.5 48.1 38.8 14.4 8.0 131.9 151.5 144.1 78.0 0.9 48.3 55.8 13.9 38.6 87.0 60.7 0.0 113.0 12.0 9.5 80.3 106.9 1.1 22.7 46.1 26.3 4.9 6.7 0.3 84.3 90.4 54.6 40.8 44.8 8.2 55.3 23.9 28.8 44.0 1.7 0.4 12.8 34.6 8.0 59.3 2.8 65.9 17.5 37.4 5.6 20.3 94.8 0.0 4.0 6.5 95.0 13.1 72.6 16.0 72.9 3.6 130.0 34.3 4.6 72.3 50.9 104.0 4.7 4.5 68.2 98.3 132.8 7.1 58.3 18.8 155.6 TRMT6 "CGI-09, GCD10, Gcd10p, MGC5029" ENSG00000089195 "TRNA methyltransferase 6" Q9UJA5 20 5937228-5950558 "Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatogonia: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047032, HPA050408" Approved Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Cell Junctions" "HPA047032: AB_2679911, HPA050408: AB_2681117" "unprognostic (1.78e-1)" "unprognostic (4.51e-2)" "unprognostic (1.65e-1)" "unprognostic (4.26e-2)" "unprognostic (2.11e-1)" "unprognostic (6.81e-2)" "prognostic unfavorable (4.70e-12)" "unprognostic (5.37e-2)" "unprognostic (3.53e-2)" "unprognostic (1.14e-1)" "unprognostic (6.27e-2)" "unprognostic (1.22e-1)" "unprognostic (7.65e-3)" "unprognostic (2.52e-2)" "unprognostic (1.76e-1)" "unprognostic (3.87e-3)" "unprognostic (4.96e-2)" 7.4 9.7 5.1 7.3 5.3 13.8 5.9 5.9 6.3 5.9 4.5 5.8 3.4 6.6 6.0 9.1 5.7 3.5 7.7 5.4 5.2 8.0 5.5 4.9 9.3 5.8 5.1 5.6 7.3 6.8 8.4 5.1 5.8 5.2 5.5 3.7 6.1 9.9 20.2 7.8 5.9 5.6 4.9 6.6 5.8 11.5 4.8 8.8 5.9 7.3 9.0 11.0 6.4 5.1 55.5 27.8 17.1 25.9 10.4 11.8 21.4 24.7 12.5 24.5 20.6 36.5 22.2 62.1 13.1 15.1 33.8 39.9 36.3 41.8 40.3 13.3 25.5 50.6 12.0 32.2 19.8 47.8 13.3 13.6 21.8 44.4 33.4 8.6 10.0 25.6 32.3 18.0 28.8 14.4 50.6 26.2 39.5 36.9 33.9 33.4 33.6 36.1 18.3 31.3 33.9 51.1 29.2 39.3 45.0 16.2 20.2 24.4 8.8 28.5 27.1 26.8 52.1 31.6 64.1 74.6 13.3 37.9 29.3 2.1 7.8 6.3 9.1 9.1 10.9 8.6 9.9 11.5 18.0 8.1 10.1 11.1 0.7 15.6 8.3 7.5 12.5 7.2 5.1 5.3 5.9 6.3 5.4 5.2 5.8 5.1 5.8 4.9 4.8 5.1 11.7 6.4 20.3 2.0 20.0 21.4 26.1 35.8 25.0 19.8 12.6 14.9 25.9 15.7 31.3 29.5 10.4 26.2 12.4 6.3 35.2 26.3 3.9 18.2 14.8 17.8 13.8 10.7 6.4 30.7 26.8 19.7 12.8 16.2 34.9 25.5 5.0 19.1 17.6 26.9 4.9 8.6 26.4 15.0 47.5 6.5 11.5 35.0 17.8 11.2 13.6 13.2 20.6 4.5 4.0 22.4 7.3 7.2 17.5 33.8 3.8 22.7 30.8 11.0 13.1 26.7 28.7 70.4 103.6 17.4 24.0 29.3 21.0 18.7 12.6 20.6 TRNAU1AP "FLJ20503, SECP43, TRSPAP1" ENSG00000180098 "TRNA selenocysteine 1 associated protein 1" Q9NX07 1 28553085-28578545 "Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032068, HPA032069" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA032068: AB_2674135, HPA032069: AB_10603998" "unprognostic (4.06e-2)" "unprognostic (1.62e-2)" "unprognostic (3.28e-2)" "prognostic favorable (2.22e-4)" "unprognostic (4.93e-2)" "unprognostic (2.28e-2)" "prognostic unfavorable (8.64e-5)" "unprognostic (5.79e-3)" "unprognostic (9.48e-3)" "unprognostic (2.24e-2)" "unprognostic (1.37e-1)" "unprognostic (2.28e-3)" "prognostic unfavorable (1.16e-5)" "unprognostic (1.84e-1)" "unprognostic (2.72e-1)" "prognostic favorable (9.45e-4)" "unprognostic (2.76e-1)" 5.8 4.7 8.2 3.9 8.5 4.1 5.2 10.1 10.5 5.2 7.7 5.8 2.7 4.2 5.5 5.2 5.0 2.5 5.4 7.9 8.5 5.3 3.3 5.2 5.9 8.4 8.2 5.8 5.6 5.7 4.0 4.1 8.5 4.3 4.4 7.2 4.8 5.1 4.0 6.9 4.7 3.7 8.1 5.3 5.1 2.9 8.2 8.5 3.8 3.4 7.0 5.0 4.6 9.2 5.1 3.0 8.6 6.0 7.7 14.6 4.1 6.7 13.5 12.1 10.9 4.7 7.8 7.7 2.6 7.4 5.7 3.8 9.4 10.7 12.1 6.8 10.6 5.8 10.1 3.2 7.1 4.5 4.8 15.7 9.2 9.5 7.4 8.5 17.4 7.8 6.8 6.1 12.0 3.5 7.7 5.2 6.1 5.5 6.5 5.5 6.0 5.4 13.3 5.1 5.0 6.5 8.0 6.9 7.7 9.1 7.7 5.4 5.0 3.1 3.0 5.0 6.1 7.9 10.6 4.8 7.6 9.7 9.1 5.4 2.7 7.3 4.2 4.5 4.2 3.6 4.5 5.3 3.3 4.1 5.3 3.4 1.6 9.7 2.8 2.2 3.3 2.2 8.2 8.5 10.1 10.5 7.9 8.5 8.4 8.2 8.5 8.1 8.2 9.2 30.3 35.3 36.6 15.0 29.2 17.6 20.0 33.8 17.6 35.1 22.3 23.0 19.9 21.5 39.9 18.4 35.5 30.6 37.1 13.4 17.6 37.4 11.1 41.0 20.4 23.8 10.3 32.2 29.7 32.8 52.8 23.0 14.8 28.0 35.4 28.1 25.4 10.8 33.1 23.5 28.2 13.9 36.7 30.1 23.2 5.0 28.9 27.6 14.2 6.5 35.1 25.5 39.1 17.6 29.9 40.8 12.2 22.6 37.5 22.2 23.4 19.5 84.7 35.4 32.9 22.0 55.0 21.9 25.3 36.3 20.5 68.4 31.8 23.1 14.8 28.9 TSG101 "TSG10, VPS23" ENSG00000074319 "Tumor susceptibility 101" Q99816 11 18468336-18526951 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Growth regulation, Host-virus interaction, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 296.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004283, HPA006161" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoli, Plasma membrane" "CAB004283: AB_671392, HPA006161: AB_1080408" "unprognostic (1.42e-1)" "unprognostic (7.91e-2)" "unprognostic (2.11e-1)" "unprognostic (6.77e-2)" "unprognostic (1.82e-1)" "unprognostic (2.72e-3)" "prognostic unfavorable (3.74e-6)" "unprognostic (5.67e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-2)" "unprognostic (4.15e-3)" "unprognostic (4.27e-2)" "prognostic favorable (5.52e-6)" "unprognostic (1.92e-2)" "unprognostic (1.02e-1)" "unprognostic (4.02e-3)" "unprognostic (1.06e-1)" 40.4 55.6 41.1 32.2 42.2 60.8 56.6 43.1 50.8 44.8 45.7 49.5 42.8 40.2 56.3 56.7 49.3 36.5 68.2 42.1 44.5 70.1 62.3 43.9 42.9 42.4 42.3 44.6 45.4 61.5 36.5 61.4 42.4 43.1 59.0 43.6 46.4 41.1 77.1 47.2 43.4 42.9 43.9 34.0 45.4 55.5 41.8 45.9 52.4 83.0 57.4 46.9 42.2 46.5 51.3 79.1 73.7 51.1 82.2 85.4 63.7 77.1 103.0 92.2 90.3 54.3 27.5 65.5 49.2 86.4 103.7 77.0 74.0 70.3 102.0 95.4 87.7 41.1 38.6 79.7 106.3 64.6 69.8 75.0 139.9 48.6 131.6 102.2 76.8 68.4 66.9 55.2 112.7 85.7 45.7 66.8 45.1 115.6 81.5 37.0 72.5 54.7 63.6 68.8 52.2 88.6 75.7 61.6 101.1 77.1 59.7 64.8 43.1 63.0 38.0 126.4 59.4 37.2 76.0 56.9 64.5 34.2 80.5 187.8 69.8 155.7 50.4 81.6 52.4 78.5 48.0 54.0 66.1 69.2 51.5 54.9 123.6 57.9 114.3 54.5 84.4 91.1 41.1 42.2 43.1 50.8 42.1 44.5 42.4 42.3 42.4 43.9 41.8 46.5 63.0 64.1 57.5 22.9 44.4 42.6 81.5 159.2 26.7 41.0 39.2 42.2 68.0 42.9 90.4 44.1 25.0 191.9 34.2 85.5 125.2 112.4 48.0 58.4 36.0 54.4 61.6 74.5 29.1 101.3 107.7 48.6 32.6 48.9 44.9 46.2 47.2 36.0 79.6 37.0 28.4 65.0 156.6 45.2 33.6 21.2 56.2 51.6 56.9 26.2 82.3 86.1 54.6 32.2 32.8 132.7 76.2 43.2 47.0 103.0 72.2 126.8 113.4 43.3 46.0 44.7 81.2 177.6 153.7 32.8 48.4 296.1 38.1 91.5 47.8 97.4 TSN "BCLF-1, REHF-1, TRSLN" ENSG00000211460 Translin Q15631 2 121737103-121767853 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059561 Uncertain Supported "Nucleoplasm,Endoplasmic reticulum" NA NA 280000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Endoplasmic reticulum" "HPA059561: AB_2684063" "unprognostic (3.15e-2)" "unprognostic (1.83e-1)" "unprognostic (3.53e-1)" "prognostic unfavorable (7.05e-4)" "unprognostic (7.13e-3)" "unprognostic (3.12e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (2.32e-2)" "unprognostic (7.58e-2)" "unprognostic (2.39e-2)" "unprognostic (1.10e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-1)" "unprognostic (6.48e-2)" "unprognostic (1.04e-2)" "unprognostic (3.42e-2)" "unprognostic (3.18e-1)" 16.2 16.9 20.9 13.5 21.9 47.8 25.4 22.7 28.4 17.4 18.9 23.3 16.9 15.8 17.9 16.6 14.2 13.2 19.5 21.0 23.6 24.4 22.9 14.3 19.1 21.3 22.4 16.7 18.4 21.7 13.1 10.8 22.3 14.5 18.8 16.6 14.9 17.2 31.6 19.3 14.6 14.2 21.4 14.7 15.0 26.2 22.0 24.1 17.2 31.0 18.2 15.6 12.8 23.8 56.2 24.8 38.4 34.1 35.0 27.8 21.1 45.6 43.2 50.3 48.4 71.1 32.3 81.7 51.9 45.4 30.1 27.0 55.0 46.6 69.8 43.2 44.3 48.0 33.0 68.3 40.0 69.3 32.5 24.2 51.3 56.3 38.7 23.0 43.2 40.0 72.9 39.4 47.4 30.5 38.2 77.5 46.6 32.8 47.2 67.6 43.1 59.3 63.7 36.0 48.9 30.6 31.4 46.6 61.2 29.2 29.3 54.1 30.8 36.2 56.4 22.9 45.1 33.8 97.0 85.4 40.3 46.8 45.6 27.6 29.8 28.6 22.5 27.9 26.9 27.4 23.4 19.8 27.4 21.0 26.5 22.9 9.3 26.9 24.3 20.1 25.6 28.8 20.9 21.9 22.7 28.4 21.0 23.6 21.3 22.4 22.3 21.4 22.0 23.8 34.7 32.1 24.4 15.0 37.5 39.1 34.4 49.1 23.3 32.1 38.2 27.6 34.7 42.9 36.9 42.3 22.9 34.9 34.3 22.3 43.0 64.4 80.0 24.9 29.7 42.7 19.9 34.7 19.8 60.0 33.3 32.5 15.8 23.9 40.0 36.0 58.5 44.4 35.2 16.8 19.8 27.7 57.0 35.6 34.9 19.8 36.4 29.8 67.6 15.0 45.4 88.7 44.3 29.1 33.5 45.4 22.2 31.2 25.4 34.7 24.4 58.7 33.0 29.5 26.3 39.9 81.8 152.8 96.6 36.7 43.9 28.5 36.8 38.5 37.9 28.8 TSR1 FLJ10534 ENSG00000167721 "TSR1 ribosome maturation factor" Q2NL82 17 2322396-2336657 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024434, HPA053087" Approved Approved Nucleoplasm NA NA 13000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA024434: AB_1858413, HPA053087: AB_2682040" "unprognostic (1.45e-2)" "unprognostic (1.43e-2)" "unprognostic (1.36e-1)" "unprognostic (1.53e-1)" "unprognostic (4.76e-2)" "unprognostic (2.74e-1)" "unprognostic (1.95e-3)" "unprognostic (9.80e-3)" "unprognostic (6.16e-2)" "unprognostic (2.38e-1)" "unprognostic (6.74e-2)" "unprognostic (1.60e-2)" "unprognostic (8.61e-2)" "unprognostic (1.40e-1)" "unprognostic (5.60e-2)" "unprognostic (1.70e-2)" "unprognostic (9.46e-3)" 18.2 10.9 11.7 17.2 12.1 15.5 17.3 11.2 12.2 10.5 11.5 13.0 9.4 14.8 12.2 20.1 12.3 10.8 17.2 11.5 11.4 12.3 14.8 10.1 15.9 11.7 11.8 15.2 19.9 16.1 8.3 14.6 11.9 13.4 14.6 14.0 12.8 13.9 49.4 19.6 9.4 18.4 12.6 11.0 11.8 18.1 12.4 15.3 11.8 30.7 19.2 22.2 11.8 12.1 80.2 85.1 39.6 77.6 31.6 36.9 80.4 65.5 36.3 39.8 30.6 138.2 33.4 85.5 54.6 52.2 36.4 70.3 86.5 76.8 50.7 39.1 97.3 63.9 66.4 65.5 44.0 59.4 42.3 37.4 48.1 76.6 87.2 43.5 39.5 45.5 84.1 46.5 49.1 49.8 56.6 29.3 94.0 60.0 50.6 59.6 55.1 57.6 49.1 52.5 27.7 61.7 57.6 43.4 45.7 37.6 40.4 26.0 43.9 54.6 43.3 65.7 122.8 33.3 45.7 49.7 53.5 67.3 67.3 1.9 7.1 1.5 8.3 10.5 11.0 7.1 6.8 7.7 11.5 8.7 7.4 9.0 1.3 6.5 11.5 4.8 9.1 6.3 11.7 12.1 11.2 12.2 11.5 11.4 11.7 11.8 11.9 12.6 12.4 12.1 13.5 32.1 29.3 7.2 21.5 34.4 42.8 18.1 31.3 16.2 18.3 13.7 17.6 12.8 30.7 14.7 18.8 29.9 17.3 7.8 3.9 27.7 68.2 18.0 32.6 20.8 10.3 30.5 7.7 16.5 39.7 24.0 18.3 24.8 43.1 24.4 12.5 13.2 16.0 18.5 6.7 12.0 10.2 12.4 10.2 73.6 13.1 14.4 16.0 3.7 18.2 12.6 10.3 3.0 6.4 23.3 5.8 12.0 23.2 35.8 4.8 11.4 21.9 19.7 19.7 36.4 27.7 29.7 47.7 42.2 41.2 24.2 16.1 25.4 15.7 33.1 TUBA1A "B-ALPHA-1, FLJ25113, TUBA3" ENSG00000167552 "Tubulin alpha 1a" Q71U36 12 49184686-49189080 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1313.3" "Cell type enhanced" "Detected in all" "Ductal cells: 1162.0;Respiratory ciliated cells: 1173.3;Smooth muscle cells: 1005.3" "Cancer enriched" "Detected in all" 9 "glioma: 942.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1660.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 3100.7;SCLC-21H: 1983.9" "Low region specificity" "Detected in all" "CAB008686, HPA039247, HPA043684, HPA063394" Enhanced Enhanced Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Microtubules "CAB008686: AB_1624202, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (3.11e-1)" "unprognostic (1.61e-1)" "unprognostic (3.77e-1)" "unprognostic (1.14e-1)" "unprognostic (4.73e-1)" "unprognostic (1.15e-2)" "unprognostic (2.56e-2)" "unprognostic (2.12e-1)" "unprognostic (3.49e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (9.79e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.07e-2)" "unprognostic (4.27e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-3)" 150.3 133.5 803.3 166.9 990.4 152.0 179.7 1083.4 882.6 185.8 692.7 466.4 54.4 406.3 166.6 140.0 342.0 193.1 156.5 784.4 1066.9 64.9 21.1 214.3 71.7 1209.8 1002.4 172.8 53.5 79.1 163.4 123.9 1136.6 173.4 126.5 259.7 104.7 267.3 37.4 107.9 125.9 865.4 1083.5 84.7 135.6 69.0 987.8 162.7 39.7 94.1 55.9 210.1 117.1 1313.3 3.2 154.4 3100.7 419.3 263.1 613.9 10.5 286.4 325.6 163.2 390.4 9.4 54.8 120.7 322.4 824.7 304.0 6.4 388.0 97.3 120.3 97.0 138.1 41.5 27.6 34.4 54.1 70.2 3.2 359.5 33.8 325.0 31.8 627.1 945.9 237.2 45.0 124.5 888.7 70.3 276.5 59.2 335.0 3.6 112.5 225.4 232.3 14.1 718.9 13.8 1983.9 1150.3 79.1 4.5 106.0 449.9 210.4 97.3 929.1 178.6 108.5 21.2 80.5 41.5 126.9 234.2 93.8 117.2 191.6 503.5 260.5 824.7 159.0 554.9 118.1 158.2 140.0 146.7 314.0 166.9 134.2 125.2 1660.9 89.9 812.8 101.1 172.8 495.5 803.3 990.4 1083.4 882.6 784.4 1066.9 1209.8 1002.4 1136.6 1083.5 987.8 1313.3 296.9 230.8 181.5 49.9 220.8 87.2 250.6 179.3 59.7 233.0 140.0 291.6 187.9 25.8 148.1 64.4 77.2 10.5 202.9 4.5 25.4 1162.0 10.0 414.9 413.6 334.2 785.8 48.0 78.2 16.2 12.8 391.5 63.2 102.4 547.9 695.0 165.6 2.8 452.0 249.0 60.6 15.5 329.6 80.7 277.6 20.7 193.6 204.2 183.2 37.5 616.6 788.9 77.2 73.4 432.6 333.3 12.8 142.6 32.5 60.4 1.5 73.3 1173.3 349.6 164.3 542.7 1005.3 15.4 31.2 20.9 99.3 15.9 266.5 40.6 12.4 95.7 TUBA4A "FLJ30169, H2-ALPHA, TUBA1" ENSG00000127824 "Tubulin alpha 4a" P68366 2 219249710-219278170 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 360.2;tongue: 210.3" "Cell type enhanced" "Detected in many" "Early spermatids: 423.0;Late spermatids: 823.0;Pancreatic endocrine cells: 613.5;Smooth muscle cells: 408.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 265.9;HBEC3-KT: 439.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004621, CAB005887, HPA039247, HPA043684, HPA063394" Approved Enhanced Microtubules NA NA 130000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 10: Non-specific - Unknown function" Microtubules "CAB004621: AB_628411, CAB005887: AB_2288001, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (8.08e-2)" "unprognostic (2.31e-1)" "unprognostic (4.03e-2)" "unprognostic (2.56e-2)" "unprognostic (5.18e-3)" "unprognostic (3.99e-2)" "prognostic unfavorable (4.54e-6)" "unprognostic (1.52e-3)" "unprognostic (4.47e-1)" "unprognostic (8.85e-2)" "unprognostic (1.49e-2)" "unprognostic (5.27e-2)" "unprognostic (1.94e-1)" "unprognostic (2.70e-1)" "unprognostic (2.36e-1)" "unprognostic (7.38e-3)" "unprognostic (9.32e-2)" 14.3 41.4 33.6 34.1 47.5 107.1 16.4 22.3 133.1 27.7 8.1 32.9 18.6 9.8 10.1 84.8 12.6 13.5 97.7 42.6 32.3 31.9 29.5 26.7 56.7 46.3 27.3 12.9 18.2 34.6 23.1 5.0 31.4 19.7 27.8 39.2 46.9 22.4 360.2 161.4 35.5 12.8 3.9 56.8 30.6 32.4 14.9 16.9 12.3 210.3 63.4 22.6 57.3 54.0 106.0 90.0 0.0 0.3 9.1 6.9 0.3 16.2 49.7 2.8 1.9 20.4 106.7 144.2 172.2 11.7 172.7 265.9 49.3 439.9 3.9 81.7 0.7 184.2 154.5 15.4 7.3 60.9 60.8 6.7 158.0 23.7 49.2 27.4 17.3 2.4 20.5 91.3 100.6 4.3 0.3 107.9 32.3 83.2 107.4 6.5 139.0 84.5 129.7 7.5 85.8 1.5 213.2 18.7 0.7 1.8 8.0 50.9 12.3 49.8 27.4 58.4 56.7 38.0 48.8 171.4 183.3 116.4 2.5 141.7 63.3 170.2 107.1 45.7 110.1 124.9 150.3 142.8 20.9 95.5 140.2 138.4 331.2 82.0 71.9 3.8 143.8 270.9 33.6 47.5 22.3 133.1 42.6 32.3 46.3 27.3 31.4 3.9 14.9 54.0 55.3 44.8 47.1 16.3 160.6 181.8 201.2 235.3 68.9 123.3 42.3 51.6 60.9 28.6 62.0 49.7 77.2 0.7 311.6 87.3 140.8 199.3 423.0 9.8 3.3 36.5 107.9 56.2 34.8 205.6 0.5 11.5 40.8 26.1 15.8 0.1 36.0 33.0 6.0 67.3 22.5 141.9 48.8 15.3 54.9 823.0 16.8 159.5 78.2 9.4 27.8 38.6 50.4 10.6 10.6 613.5 51.2 7.5 202.3 46.7 87.5 137.5 11.1 72.9 0.0 21.1 408.5 5.7 5.0 130.6 244.5 2.5 290.1 1.4 58.9 113.0 TUBB "M40, MGC16435, OK/SW-cl.56, Tubb5" ENSG00000196230 "Tubulin beta class I" P07437 6 30717435-30725538 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 2296.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005417, CAB012406, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 170000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB005417: AB_2241191, CAB012406: AB_2210370, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (1.01e-1)" "unprognostic (2.33e-1)" "unprognostic (2.17e-3)" "unprognostic (1.92e-2)" "unprognostic (1.56e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (2.18e-3)" "unprognostic (1.27e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (2.62e-8)" "unprognostic (8.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" 229.5 164.8 74.6 243.5 81.8 541.0 186.9 46.2 367.7 228.7 87.0 250.3 87.6 333.0 174.5 246.3 227.0 158.5 245.3 73.5 119.7 137.8 236.6 205.3 369.2 80.5 74.8 467.5 138.1 74.4 97.0 194.4 99.2 145.2 194.4 82.4 160.2 194.6 185.7 211.9 159.4 371.0 57.5 195.0 172.8 77.8 94.0 620.4 142.4 98.6 487.6 222.3 213.8 63.5 2281.7 1027.3 2650.0 1458.4 733.2 1265.2 568.2 396.9 469.5 943.3 863.5 1329.2 703.9 1494.1 1105.1 1408.1 1877.8 805.3 2160.6 1968.0 160.3 892.5 1321.1 461.4 207.3 1306.7 345.8 2550.0 1223.9 943.6 455.9 416.0 443.6 967.1 1493.3 2058.1 1270.4 294.1 1844.8 1398.2 2719.0 249.3 377.3 604.1 948.6 102.6 708.5 911.6 1564.5 1071.4 940.8 1516.7 969.0 911.2 354.7 1625.5 1148.3 422.4 880.6 2712.0 1526.0 614.5 917.7 835.3 1735.4 2101.3 538.8 2494.6 3548.7 119.8 115.6 122.8 187.3 182.5 218.8 166.1 152.3 188.8 111.7 113.0 143.2 163.3 46.8 165.1 222.4 227.7 180.8 342.5 74.6 81.8 46.2 367.7 73.5 119.7 80.5 74.8 99.2 57.5 94.0 63.5 215.8 131.4 47.3 21.5 214.9 576.2 358.4 698.6 434.2 72.7 234.2 312.8 114.9 244.5 238.7 171.0 39.6 811.9 198.7 133.4 311.0 1091.0 9.1 69.1 261.6 370.8 163.6 1322.1 28.2 1061.1 2296.1 471.5 95.3 140.2 207.3 643.6 298.4 267.8 955.2 109.4 25.0 185.3 376.4 454.5 689.6 24.4 402.6 295.8 321.9 30.9 774.0 192.6 246.1 20.1 23.0 1087.0 90.7 237.3 304.6 199.5 117.9 245.9 66.6 65.4 118.3 124.0 838.6 58.0 126.5 447.0 430.6 220.4 244.0 224.9 253.2 229.0 TXNDC9 APACD ENSG00000115514 "Thioredoxin domain containing 9" O14530 2 99318982-99340702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031844, HPA031845, HPA031846" Approved Enhanced Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA031844: AB_10600838, HPA031845: AB_10670968, HPA031846: AB_10669916" "unprognostic (3.63e-3)" "unprognostic (4.26e-2)" "unprognostic (7.28e-2)" "unprognostic (3.12e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (9.63e-7)" "unprognostic (2.06e-2)" "unprognostic (9.09e-2)" "unprognostic (1.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.32e-1)" "unprognostic (2.47e-3)" "unprognostic (2.03e-1)" "unprognostic (1.14e-1)" "unprognostic (1.29e-1)" 18.7 17.9 10.0 21.3 10.8 17.5 28.7 11.0 13.2 19.3 10.4 24.6 18.4 16.6 25.9 26.1 18.1 18.6 28.6 10.8 11.7 28.8 27.2 20.1 29.2 11.6 11.5 10.7 10.9 15.4 11.3 23.5 11.9 19.6 26.3 11.0 15.1 16.1 18.2 19.0 17.6 24.4 11.8 18.6 18.5 17.8 10.9 26.1 24.8 16.2 34.0 24.9 14.1 12.5 78.3 27.6 55.0 27.7 55.8 57.8 65.8 83.1 79.5 88.5 85.0 71.1 55.5 58.0 66.9 72.6 77.0 52.7 55.2 88.2 102.6 44.0 53.5 60.4 34.5 77.0 54.2 71.8 44.2 53.0 76.7 74.3 53.8 46.1 101.9 32.1 73.0 51.1 103.7 41.5 43.4 63.6 43.4 46.4 68.7 32.5 53.0 56.4 123.9 62.6 37.1 31.5 41.7 56.2 93.7 69.8 64.3 60.9 69.4 65.1 62.7 40.6 62.6 21.2 37.1 65.6 51.9 76.8 58.6 110.6 54.1 61.1 56.7 60.5 70.2 69.1 66.6 64.4 60.3 57.6 61.9 62.5 53.5 77.7 82.6 60.9 91.2 87.0 10.0 10.8 11.0 13.2 10.8 11.7 11.6 11.5 11.9 11.8 10.9 12.5 46.6 9.6 13.4 8.8 33.4 35.2 29.7 137.1 25.0 11.3 21.5 26.3 27.6 25.8 67.0 36.8 8.4 75.7 31.3 26.2 84.1 79.8 75.7 37.3 29.9 46.2 20.9 47.8 13.3 69.4 82.5 29.2 22.4 25.5 17.7 21.0 38.2 24.4 56.9 13.5 12.8 25.7 91.6 25.4 31.3 21.1 27.7 30.2 26.6 4.7 55.5 26.9 44.3 12.5 16.7 84.5 21.6 23.3 31.8 24.0 21.9 121.5 72.8 19.8 26.3 17.8 89.3 52.8 42.7 29.4 38.9 81.3 35.1 40.1 26.6 21.9 TXNL1 "TRP32, Txl, TXNL" ENSG00000091164 "Thioredoxin like 1" O43396 18 56597209-56651600 "Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002828, HPA002829, CAB016446" Supported Supported Enhanced Cytosol NA Yes 1100000 "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016446: , HPA002828: AB_1858358, HPA002829: AB_1858359" "unprognostic (2.05e-1)" "unprognostic (2.97e-1)" "unprognostic (3.38e-3)" "unprognostic (4.54e-2)" "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (9.62e-6)" "unprognostic (1.83e-1)" "unprognostic (1.03e-2)" "prognostic favorable (6.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (3.29e-3)" "unprognostic (1.24e-1)" "unprognostic (1.26e-1)" "unprognostic (2.62e-1)" "unprognostic (1.51e-1)" 38.3 55.9 45.4 38.6 47.5 83.0 49.1 49.1 63.6 42.5 40.1 41.7 42.1 38.3 66.9 54.2 35.2 40.0 80.0 50.0 50.9 51.7 80.7 30.6 41.2 47.7 47.2 47.1 62.2 51.4 38.2 48.1 49.5 40.5 43.4 77.9 48.5 39.3 149.0 36.5 40.6 43.4 46.2 32.2 46.7 41.9 47.5 48.0 197.9 146.8 49.9 51.8 35.1 54.0 77.7 74.8 99.2 102.8 83.2 121.6 70.2 90.2 91.8 113.4 95.4 67.0 74.2 83.4 78.1 98.4 82.3 93.7 94.4 81.3 116.9 85.7 43.1 114.9 58.3 127.1 98.3 168.9 71.7 92.9 82.4 107.4 97.4 118.8 93.0 62.9 85.5 136.0 116.0 74.4 98.1 109.8 71.9 53.5 79.6 78.2 66.8 145.9 133.0 118.6 81.6 74.5 51.3 70.9 88.1 78.3 77.5 89.1 74.3 118.7 62.9 41.9 89.5 130.8 151.1 130.5 77.2 127.0 89.1 98.5 63.1 48.3 26.9 55.8 37.2 38.9 33.0 35.8 54.8 35.4 32.0 32.9 48.3 43.3 54.9 47.0 42.9 61.5 45.4 47.5 49.1 63.6 50.0 50.9 47.7 47.2 49.5 46.2 47.5 54.0 89.7 57.7 45.9 25.5 80.0 134.3 123.1 177.1 75.7 82.7 89.3 110.4 110.1 67.2 108.3 29.5 139.7 242.3 82.7 72.2 109.5 150.5 246.9 88.0 90.0 84.2 75.9 153.8 43.8 128.3 130.9 86.1 52.0 90.3 53.2 167.5 52.8 78.0 150.1 57.2 43.6 111.6 77.3 97.3 97.0 294.1 77.6 90.5 65.8 15.9 121.8 86.0 78.2 26.2 55.6 139.5 83.7 83.8 88.9 121.2 110.0 144.7 75.1 97.1 65.7 73.0 167.1 204.1 108.0 93.9 126.0 358.6 72.4 171.0 109.7 123.1 U2SURP "fSAPa, SR140" ENSG00000163714 "U2 snRNP associated SURP domain containing" O15042 3 142964497-143060725 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037545, HPA037546, HPA061407" Enhanced Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA037545: AB_10672598, HPA037546: AB_2675535, HPA061407: AB_2684506" "unprognostic (2.01e-1)" "unprognostic (9.78e-2)" "unprognostic (8.09e-2)" "prognostic unfavorable (8.44e-4)" "unprognostic (3.11e-2)" "unprognostic (4.30e-2)" "prognostic unfavorable (3.15e-5)" "unprognostic (3.72e-2)" "unprognostic (1.98e-2)" "unprognostic (9.61e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (2.85e-3)" "prognostic unfavorable (8.86e-7)" "unprognostic (6.71e-2)" "unprognostic (2.19e-1)" "unprognostic (3.12e-1)" "prognostic favorable (6.78e-4)" 22.1 18.2 16.6 19.3 17.1 57.6 23.4 21.9 25.1 25.0 15.9 21.3 12.9 22.6 20.8 21.5 23.9 12.3 18.1 16.2 16.8 23.2 24.3 18.8 29.9 16.4 16.1 31.7 25.2 22.5 21.5 17.8 16.6 19.8 20.1 51.8 18.5 14.5 27.4 21.9 22.0 17.5 15.1 25.7 19.9 20.4 16.2 31.3 22.5 17.7 26.1 20.9 21.9 20.8 165.4 54.2 59.7 40.1 30.9 28.3 103.9 72.8 46.4 82.2 61.2 72.7 49.7 189.2 76.0 47.5 157.0 58.2 124.0 66.1 93.2 51.8 88.0 205.1 49.9 58.3 31.7 202.1 75.3 34.4 32.0 64.3 81.9 36.4 45.4 118.5 129.5 59.1 39.0 46.3 100.4 86.8 96.7 52.8 50.4 101.9 116.2 79.0 40.8 102.8 76.5 44.5 146.1 48.2 87.1 61.2 85.3 84.8 49.5 44.1 52.2 35.1 118.0 69.4 97.5 319.8 34.9 72.1 63.1 40.2 32.7 33.3 40.9 31.7 35.1 60.1 37.1 37.0 27.0 60.7 42.4 36.6 33.3 35.5 48.2 53.9 40.5 21.6 16.6 17.1 21.9 25.1 16.2 16.8 16.4 16.1 16.6 15.1 16.2 20.8 124.4 118.6 129.4 116.2 94.8 60.8 85.7 140.5 68.9 124.2 64.4 90.3 123.8 52.9 115.6 62.5 66.7 78.9 109.9 50.0 52.8 77.2 35.1 91.5 129.4 96.4 55.2 126.0 71.7 79.8 83.7 103.8 58.1 99.1 98.1 165.5 62.8 58.5 61.3 92.5 80.7 74.7 85.5 60.2 54.6 22.0 108.7 78.4 51.6 63.7 115.9 98.1 110.2 104.5 145.8 89.6 55.7 79.7 108.7 81.9 48.0 60.6 100.2 125.4 78.9 122.8 139.4 243.6 235.6 76.9 64.8 79.1 98.6 111.6 80.7 78.4 UAP1L1 ENSG00000197355 "UDP-N-acetylglucosamine pyrophosphorylase 1 like 1" Q3KQV9 9 137077517-137084539 "Metabolic proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 21.7;Horizontal cells: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HHSteC: 58.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044356 Approved Approved "Intermediate filaments,Cytosol" No No "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Intermediate filaments" Cytosol "HPA044356: AB_10959902" "unprognostic (1.93e-1)" "unprognostic (1.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.25e-3)" "unprognostic (2.49e-2)" "unprognostic (3.80e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (3.01e-2)" "unprognostic (2.33e-1)" "unprognostic (5.65e-2)" "prognostic favorable (5.23e-4)" "unprognostic (1.22e-1)" "unprognostic (5.06e-2)" "unprognostic (1.67e-2)" "unprognostic (6.42e-2)" "unprognostic (3.28e-2)" "unprognostic (5.64e-3)" 11.6 14.1 13.5 5.5 18.7 3.1 9.5 14.3 16.4 15.0 15.8 8.1 5.7 6.7 5.1 6.0 7.6 5.3 11.0 14.4 14.0 14.0 2.8 12.5 7.9 16.6 15.8 3.8 9.6 7.9 15.4 6.3 15.8 13.0 3.6 2.9 11.0 5.6 2.7 10.1 10.8 3.5 12.6 22.0 10.2 3.2 19.0 2.4 14.1 2.7 5.9 10.0 9.1 24.1 0.8 5.8 0.0 15.7 26.4 12.1 4.5 8.1 21.1 22.4 15.4 11.7 2.6 3.7 4.7 8.3 40.6 12.1 29.6 2.0 4.6 10.0 2.7 7.9 9.5 11.3 58.5 0.1 31.5 8.9 2.1 12.7 10.4 10.4 17.7 7.3 2.4 18.0 15.2 13.5 0.8 8.1 2.6 28.3 8.3 12.8 0.2 11.3 8.9 1.1 9.3 5.8 2.0 44.3 18.7 3.7 23.9 21.8 14.1 40.2 8.6 28.3 3.9 19.6 30.1 7.9 34.9 8.6 11.7 0.1 1.0 0.0 0.2 0.5 0.8 0.5 0.1 0.3 0.5 0.2 0.2 0.3 0.1 0.0 0.0 0.3 0.5 0.4 13.5 18.7 14.3 16.4 14.4 14.0 16.6 15.8 15.8 12.6 19.0 24.1 2.4 0.0 8.4 16.0 6.9 6.1 0.6 2.0 4.0 6.8 4.8 3.9 4.0 5.7 1.5 0.0 2.1 0.4 7.1 2.1 11.7 1.4 0.2 2.2 4.9 3.1 1.8 0.4 3.3 0.9 5.0 4.0 1.1 3.4 4.5 0.8 7.1 0.7 21.7 20.2 5.1 1.8 6.1 10.9 9.9 0.2 2.5 11.2 8.8 6.5 9.1 4.7 3.1 6.6 18.4 0.8 1.9 3.8 5.6 2.0 0.5 3.4 1.1 5.1 0.0 3.0 16.5 0.6 1.5 3.5 4.4 1.4 4.5 1.0 3.1 0.2 UBAP2L "KIAA0144, NICE-4" ENSG00000143569 "Ubiquitin associated protein 2 like" Q14157 1 154220179-154271510 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 147.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035068 Approved Approved "Nuclear speckles,Cytosol" NA NA 67000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytosol" "HPA035068: AB_10696366" "unprognostic (3.14e-2)" "unprognostic (1.50e-1)" "unprognostic (8.82e-2)" "unprognostic (2.93e-3)" "unprognostic (3.98e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (4.65e-5)" "unprognostic (1.97e-2)" "unprognostic (5.10e-3)" "unprognostic (9.01e-2)" "unprognostic (1.67e-1)" "unprognostic (6.96e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (7.40e-3)" "unprognostic (9.14e-2)" "unprognostic (2.69e-1)" "unprognostic (3.72e-1)" 54.1 49.3 30.7 60.9 31.3 62.8 50.0 29.2 40.4 52.2 32.5 53.2 34.2 59.8 48.6 55.0 54.6 44.8 62.7 32.0 31.2 39.8 36.6 54.5 60.7 26.3 27.6 60.5 37.9 60.4 49.4 70.6 26.3 45.7 40.8 46.0 48.0 47.1 83.1 60.2 40.6 55.2 20.4 53.6 45.9 64.5 27.2 59.5 53.6 49.1 65.9 54.0 50.9 35.0 189.3 184.8 167.4 136.5 121.0 138.0 148.1 212.1 154.9 187.6 131.6 197.9 143.6 235.3 213.2 178.9 94.6 160.8 224.3 158.4 167.7 208.1 199.7 255.7 184.6 162.7 113.7 269.6 144.0 130.5 68.3 173.8 114.8 117.9 153.1 92.0 235.0 111.5 152.6 212.6 207.8 101.1 320.4 140.1 170.9 148.9 135.5 207.8 120.7 220.5 173.1 209.3 245.1 227.2 91.4 186.8 226.6 180.6 245.9 117.0 123.8 145.1 205.7 239.1 278.4 313.2 125.7 144.8 179.0 15.1 28.2 20.4 23.1 35.9 25.4 20.9 21.8 21.2 34.9 26.4 24.6 27.7 24.5 36.4 41.3 16.3 21.5 29.6 30.7 31.3 29.2 40.4 32.0 31.2 26.3 27.6 26.3 20.4 27.2 35.0 29.2 25.6 38.5 22.9 31.7 18.4 18.7 21.5 22.2 18.4 21.5 21.5 39.0 17.2 32.3 18.4 8.4 51.3 32.7 16.7 17.6 28.4 80.6 34.3 43.8 26.8 23.4 34.9 26.7 27.1 39.5 29.0 21.9 35.7 24.7 32.3 23.2 19.1 36.1 15.2 25.3 21.7 26.4 22.6 30.2 147.1 21.5 32.4 19.6 26.2 24.5 13.7 24.7 29.1 29.1 30.9 10.4 22.6 20.6 25.1 12.5 15.9 29.7 20.4 13.1 31.1 51.6 42.2 48.8 31.7 20.5 77.8 23.5 35.6 22.0 21.9 UBB "FLJ25987, MGC8385" ENSG00000170315 "Ubiquitin B" P0CG47 17 16380798-16382745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013048, HPA041344, HPA049132" Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "CAB013048: AB_2533002, HPA041344: AB_2677422, HPA049132: AB_2680646" "unprognostic (1.16e-1)" "unprognostic (2.98e-1)" "unprognostic (2.55e-1)" "unprognostic (7.34e-2)" "unprognostic (3.86e-1)" "unprognostic (9.32e-2)" "unprognostic (1.29e-3)" "unprognostic (2.48e-2)" "unprognostic (5.81e-2)" "unprognostic (2.15e-3)" "unprognostic (2.88e-2)" "unprognostic (1.45e-2)" "prognostic favorable (1.07e-4)" "unprognostic (1.02e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" 942.4 1676.7 1564.8 674.6 1589.2 2376.9 770.4 1662.2 2231.7 812.8 1565.4 1065.5 1179.6 788.9 1367.0 656.3 656.8 813.0 1668.3 1644.2 1719.8 1593.6 2982.1 1046.3 1002.7 1672.3 1765.4 726.2 1305.1 1677.7 1373.8 1012.3 1713.9 808.0 1097.8 566.0 1294.6 861.8 2656.6 692.3 1134.0 932.4 1670.6 1078.8 1245.6 1591.8 1597.4 1226.8 1181.5 2162.1 993.0 974.7 689.1 1980.8 1646.5 3022.4 1559.8 1912.1 1530.0 963.9 1131.3 1609.5 2166.2 2855.8 2453.4 2916.5 1270.4 1662.3 2631.3 1916.6 1678.5 1295.4 0.8 1054.2 3076.0 2126.4 2231.3 1649.8 1653.1 2183.7 1022.3 6.6 2162.4 1468.9 1010.2 2183.4 848.2 1486.0 1582.3 1562.2 1888.9 1530.9 1743.0 3858.5 2354.7 2086.6 1288.4 4642.0 1177.2 2185.1 1984.7 1484.1 2312.8 1911.4 1179.0 1757.0 2109.6 1239.7 1454.4 3025.5 1392.6 1936.0 1152.7 1417.8 867.8 1087.6 2507.7 845.7 1238.7 1366.4 1688.3 1757.9 1356.3 5348.4 1684.4 3262.9 2632.2 2121.6 2131.1 3065.4 2048.1 2372.7 1501.1 2872.4 1787.4 2146.5 981.5 3290.2 1875.7 2799.7 2592.8 7841.1 1564.8 1589.2 1662.2 2231.7 1644.2 1719.8 1672.3 1765.4 1713.9 1670.6 1597.4 1980.8 1607.0 1003.2 1168.4 46.7 786.3 979.5 1548.2 1890.9 796.2 426.2 763.6 1161.1 370.3 948.0 1262.5 551.8 120.9 1661.1 1082.7 1377.9 1829.3 1114.8 3648.2 961.6 510.0 870.9 922.4 4506.0 29.1 880.2 996.8 1202.3 1270.6 799.9 1800.7 412.4 669.3 1509.8 1168.9 233.9 37.3 1351.2 1310.2 589.0 1180.7 2126.9 592.4 826.6 1812.5 50.6 1001.9 912.0 1051.5 30.7 133.6 751.3 1879.5 775.2 700.4 974.6 1970.0 3101.7 2080.6 506.8 880.9 714.4 3554.9 3297.7 1090.7 739.1 1112.3 1815.4 1231.6 935.0 993.8 1036.2 UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371469-134392108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 265.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 723.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 444.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 444.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (1.64e-3)" "unprognostic (6.30e-3)" "unprognostic (3.42e-2)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" 52.5 74.2 31.5 50.0 33.1 84.4 44.2 36.3 53.2 38.3 30.2 48.0 40.7 53.6 34.8 70.5 37.3 51.0 118.4 34.3 34.8 50.6 56.6 44.9 47.1 29.5 31.0 44.4 53.7 25.8 39.9 48.4 31.0 32.9 42.0 29.2 39.7 23.2 265.8 43.1 46.4 43.3 30.3 43.7 39.6 49.2 32.9 29.3 41.2 99.8 48.1 42.8 43.2 36.7 109.4 27.9 58.2 55.0 50.0 54.1 92.7 80.2 43.5 51.4 60.9 85.6 70.9 58.7 94.1 52.3 138.7 42.7 45.8 60.4 56.0 94.5 47.6 32.1 75.9 92.8 58.2 38.8 63.7 46.5 80.2 47.4 39.3 68.1 44.1 48.8 61.1 103.5 46.8 63.4 62.5 102.1 24.9 32.6 26.7 61.6 63.8 83.8 46.6 82.9 77.6 60.1 62.9 29.3 147.9 62.5 63.0 106.0 87.6 57.8 40.8 78.9 89.4 86.1 129.4 87.0 65.2 72.8 59.4 236.7 58.3 174.0 46.9 68.3 42.9 49.7 58.8 48.1 42.6 47.9 69.9 60.6 444.6 53.0 78.9 48.0 77.5 64.1 31.5 33.1 36.3 53.2 34.3 34.8 29.5 31.0 31.0 30.3 32.9 36.7 187.5 73.7 61.6 40.1 176.5 364.7 321.2 215.1 175.8 77.8 169.9 156.5 315.8 147.3 113.7 75.4 81.3 144.5 182.0 183.1 172.1 173.8 233.2 139.8 102.2 149.7 131.8 261.2 103.0 169.5 123.0 183.3 113.2 167.8 116.8 81.7 115.3 97.4 119.4 87.5 84.2 141.0 181.0 131.5 323.9 315.4 155.0 184.2 227.7 49.6 190.6 150.0 113.3 44.7 68.4 210.6 195.2 113.2 162.5 343.9 153.4 170.7 111.7 91.3 151.2 154.9 262.9 223.5 201.7 145.5 369.7 723.5 192.0 140.4 105.7 488.1 UBE2D3 UbcH5C ENSG00000109332 "Ubiquitin conjugating enzyme E2 D3" P61077 4 102794383-102868896 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (7.43e-2)" "unprognostic (3.19e-1)" "unprognostic (1.27e-2)" "unprognostic (5.78e-2)" "unprognostic (6.44e-2)" "unprognostic (4.96e-2)" "unprognostic (1.17e-1)" "unprognostic (8.44e-3)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.75e-2)" "unprognostic (3.31e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.08e-2)" "unprognostic (2.79e-1)" "unprognostic (4.54e-2)" "unprognostic (1.34e-2)" 182.7 171.7 85.7 172.0 92.6 478.3 141.9 101.1 120.6 127.1 93.4 154.9 154.0 125.3 113.8 173.4 125.9 142.5 149.4 92.1 103.9 172.2 251.4 175.3 189.6 102.5 96.0 131.5 154.2 133.5 98.4 159.0 99.8 106.8 144.4 129.0 116.7 102.1 243.6 136.4 158.3 129.9 101.4 149.5 144.4 127.0 95.6 198.5 159.2 197.9 197.0 185.6 128.0 113.7 301.6 169.1 275.4 223.4 286.2 408.0 235.9 301.2 395.1 260.1 243.6 257.4 416.4 319.3 190.6 304.4 336.8 168.6 294.7 400.8 352.5 299.6 149.8 292.0 165.8 209.6 300.3 415.5 240.4 314.0 247.9 288.6 398.9 334.3 343.4 258.7 372.9 316.4 350.9 243.1 613.4 235.1 200.2 341.0 167.1 318.4 269.9 231.5 261.5 283.7 275.6 232.1 183.5 464.8 349.6 318.2 193.0 241.0 318.4 270.0 231.1 179.2 276.3 277.9 389.8 491.3 288.2 227.2 297.0 614.9 253.7 394.0 163.5 256.0 216.3 165.9 203.4 194.4 217.6 139.2 205.8 190.5 817.2 215.7 271.9 149.8 229.6 422.1 85.7 92.6 101.1 120.6 92.1 103.9 102.5 96.0 99.8 101.4 95.6 113.7 303.4 166.7 193.1 98.9 291.7 844.0 693.9 408.2 233.9 133.7 251.5 166.9 229.8 193.0 242.3 139.8 125.1 311.5 317.4 336.1 547.8 361.0 779.4 257.1 246.7 344.0 240.8 348.7 159.7 382.2 561.6 286.0 202.3 371.3 224.9 154.8 193.1 235.7 392.9 122.8 145.8 283.8 303.2 403.0 825.6 635.1 164.7 415.1 357.5 111.5 399.4 160.0 280.2 104.5 185.0 454.4 347.2 149.0 296.4 612.3 335.8 428.8 242.4 170.6 105.2 270.6 531.9 217.2 180.7 258.2 813.3 638.4 382.5 172.3 268.2 784.3 UBE2E3 UbcH9 ENSG00000170035 "Ubiquitin conjugating enzyme E2 E3" Q969T4 2 180967248-181076585 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 654.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003303, HPA030445" Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" "HPA003303: AB_1858521, HPA030445: AB_10669599" "unprognostic (8.85e-2)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.08e-5)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.00e-3)" "unprognostic (4.99e-2)" "unprognostic (8.46e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (8.75e-2)" "unprognostic (3.86e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (2.18e-1)" "unprognostic (4.40e-1)" 61.6 45.8 57.8 40.1 60.8 48.3 58.1 59.9 71.5 56.2 51.4 51.4 46.7 51.6 55.8 46.7 58.3 71.4 54.2 74.3 59.7 71.8 58.3 39.9 39.6 56.6 57.8 52.5 56.5 79.4 35.3 48.6 58.0 40.0 54.4 68.4 54.6 39.6 175.1 57.0 42.5 42.9 62.3 40.3 59.2 56.8 58.8 67.9 73.7 88.6 48.4 61.6 46.9 64.1 104.8 46.6 654.4 22.8 189.8 243.1 104.0 137.1 171.9 112.8 139.2 51.0 124.0 51.4 117.1 188.5 94.5 43.8 400.7 140.5 202.1 125.9 120.3 177.2 59.0 142.5 91.6 83.5 81.3 96.7 127.9 99.3 94.8 114.6 150.9 105.4 91.9 93.3 280.7 57.5 152.6 77.7 125.6 71.2 217.6 147.0 66.8 122.1 193.2 91.1 113.4 126.3 59.7 62.8 58.1 178.3 33.7 121.5 140.1 218.2 143.2 129.4 162.0 81.1 55.0 143.7 215.7 32.6 124.3 29.1 28.2 53.7 17.6 25.4 21.3 15.0 13.6 22.7 18.4 9.5 14.3 15.7 25.6 18.5 36.3 60.0 5.9 20.5 57.8 60.8 59.9 71.5 74.3 59.7 56.6 57.8 58.0 62.3 58.8 64.1 69.3 9.6 24.2 100.9 50.3 102.9 83.7 111.2 70.6 151.8 84.4 74.4 37.7 108.7 63.7 55.2 29.2 31.9 84.8 56.4 229.0 95.8 36.9 54.3 51.6 59.8 59.8 108.8 115.4 101.9 83.4 81.2 60.6 57.8 23.5 61.8 72.1 55.9 85.3 75.7 67.7 39.4 91.6 71.4 63.9 79.7 62.7 76.3 129.9 71.2 62.4 103.9 79.3 160.9 158.3 113.7 41.6 36.1 87.7 74.8 58.9 172.6 51.8 73.3 26.3 56.4 81.7 83.1 191.6 77.3 122.3 36.0 55.4 57.9 50.9 103.4 UBE2I UBC9 ENSG00000103275 "Ubiquitin conjugating enzyme E2 I" P63279 16 1308880-1327018 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003909, CAB009021, CAB079920" Approved Supported Nucleoplasm,Nucleoli NA NA 130000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "CAB009021: AB_2210610, CAB079920: AB_2809487, HPA003909: AB_1858529" "unprognostic (2.12e-1)" "unprognostic (1.01e-2)" "unprognostic (1.55e-2)" "unprognostic (3.51e-1)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (2.88e-3)" "unprognostic (1.20e-1)" "unprognostic (1.89e-2)" "unprognostic (7.60e-3)" "unprognostic (3.56e-1)" "unprognostic (7.28e-2)" "unprognostic (9.30e-2)" "unprognostic (1.57e-1)" "prognostic favorable (5.68e-4)" "unprognostic (1.15e-3)" 62.5 76.3 42.5 60.3 44.0 81.6 62.0 46.1 49.3 64.7 37.1 63.8 45.1 72.7 48.7 74.2 67.3 34.3 68.2 45.2 45.2 63.4 40.8 53.1 76.0 39.3 42.3 93.1 49.1 72.0 61.6 58.1 40.2 53.4 47.3 31.7 56.4 46.7 58.0 68.0 61.1 53.8 42.2 71.9 52.9 47.6 47.1 110.3 53.2 57.0 89.3 66.6 63.1 42.1 121.3 161.1 269.0 157.7 112.7 135.8 114.4 170.0 121.7 154.3 152.9 191.8 190.1 208.2 137.7 148.1 140.7 142.4 193.2 159.2 197.9 151.2 133.4 130.6 136.6 188.4 178.6 194.9 148.0 127.1 100.7 152.1 180.0 149.0 170.0 169.9 190.3 124.3 148.0 254.4 349.6 193.0 219.0 136.0 118.5 434.0 170.9 238.4 145.7 106.6 150.3 159.8 149.3 164.1 177.7 152.8 167.5 234.4 139.4 149.2 172.6 134.0 155.5 132.1 170.4 423.4 85.3 142.9 164.7 278.7 214.3 327.1 165.9 256.6 200.9 297.8 167.8 170.3 214.7 241.1 148.2 149.6 149.5 202.6 249.5 186.3 196.5 260.9 42.5 44.0 46.1 49.3 45.2 45.2 39.3 42.3 40.2 42.2 47.1 42.1 109.5 51.3 67.0 16.3 172.8 178.6 186.4 275.6 97.3 64.6 101.9 105.7 89.1 84.4 140.9 62.5 50.1 312.8 153.9 77.4 105.7 211.9 64.4 66.6 100.6 118.3 102.3 127.4 17.2 148.2 293.1 134.4 55.5 104.6 109.5 149.7 94.2 43.7 213.5 47.1 16.8 97.1 162.8 104.8 182.1 37.8 129.8 124.8 128.1 15.9 220.2 104.7 209.1 16.6 26.7 212.3 91.8 107.6 144.1 294.8 90.4 117.7 65.7 63.1 78.9 82.1 185.4 139.6 145.7 158.4 206.7 418.1 144.7 134.9 134.7 304.5 UBE2K "HIP2, HYPG, UBC1" ENSG00000078140 "Ubiquitin conjugating enzyme E2 K" P61086 4 39698109-39782792 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028869, CAB033212, CAB033515" Supported Approved "Plasma membrane,Cytosol" NA NA 390000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Plasma membrane" "CAB033212: AB_2272506, CAB033515: AB_2304024, HPA028869: AB_10602487" "unprognostic (1.14e-2)" "unprognostic (6.02e-2)" "unprognostic (2.42e-3)" "unprognostic (3.06e-1)" "unprognostic (6.81e-2)" "unprognostic (2.05e-1)" "unprognostic (5.05e-3)" "unprognostic (1.44e-2)" "unprognostic (2.71e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (8.60e-4)" "unprognostic (1.08e-1)" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (4.10e-3)" 29.9 19.4 13.5 23.4 17.5 21.4 21.7 20.9 24.5 16.0 9.2 35.8 31.2 17.8 17.7 26.2 12.7 12.9 18.4 18.3 14.9 26.7 45.4 16.4 20.1 12.9 14.0 13.6 13.2 20.4 15.8 24.4 13.1 19.8 24.2 21.0 16.9 14.9 37.3 22.6 24.8 17.2 7.8 18.0 31.8 16.5 14.2 22.4 23.8 25.6 18.0 20.2 17.2 16.0 91.3 90.7 49.3 45.6 29.8 28.7 82.8 122.8 26.4 32.8 34.0 138.0 91.1 114.3 105.2 35.0 79.8 39.0 95.4 54.7 51.9 76.1 70.0 145.7 88.9 121.6 38.4 159.0 79.6 27.1 60.2 46.0 49.0 35.2 43.3 49.3 152.9 39.6 33.9 86.6 111.5 89.9 67.7 54.4 69.8 66.3 144.0 44.2 46.0 123.9 103.9 47.4 91.7 34.5 58.9 54.1 44.4 58.2 116.9 49.9 105.7 60.0 114.5 55.3 174.0 121.4 26.9 101.4 59.5 19.6 18.1 24.8 14.4 16.9 13.4 20.7 15.0 13.8 19.7 14.7 11.2 12.6 15.1 14.0 25.4 27.6 16.0 10.5 13.5 17.5 20.9 24.5 18.3 14.9 12.9 14.0 13.1 7.8 14.2 16.0 63.2 57.7 63.1 69.2 53.0 122.9 65.5 74.3 59.7 62.2 65.3 52.5 72.3 52.9 66.7 49.7 29.2 84.5 76.5 143.7 66.5 83.5 144.9 72.0 82.3 65.6 59.7 85.8 115.9 89.4 168.7 59.2 68.3 90.9 34.8 40.1 63.5 113.6 80.2 104.3 113.8 74.5 65.1 77.1 91.8 202.4 65.3 76.5 56.9 89.0 104.0 87.1 56.7 87.0 118.2 139.6 94.3 56.4 55.5 111.4 75.3 98.0 60.7 42.9 39.5 61.8 121.1 145.2 55.1 74.3 137.9 147.5 61.3 54.8 74.1 107.0 UBE2Q1 "NICE-5, PRO3094, UBE2Q" ENSG00000160714 "Ubiquitin conjugating enzyme E2 Q1" Q7Z7E8 1 154548577-154559028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063368 Approved Approved Nucleoplasm,Centrosome,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Centrosome, Cytosol" "HPA063368: AB_2684996" "unprognostic (3.88e-1)" "unprognostic (2.13e-1)" "unprognostic (4.44e-3)" "unprognostic (3.64e-3)" "unprognostic (5.32e-3)" "unprognostic (6.10e-3)" "prognostic unfavorable (8.74e-4)" "unprognostic (2.92e-1)" "unprognostic (2.07e-1)" "unprognostic (9.92e-3)" "unprognostic (3.79e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.84e-7)" "unprognostic (2.20e-1)" "unprognostic (4.46e-1)" "prognostic favorable (1.86e-5)" "unprognostic (1.04e-2)" 25.4 23.1 36.1 19.0 37.0 32.2 22.4 34.5 43.3 21.2 35.2 24.3 18.7 21.8 27.2 27.4 23.7 19.9 25.9 37.3 38.0 28.8 31.6 25.0 29.5 36.0 36.0 23.1 31.8 28.3 31.3 23.9 37.5 21.2 28.2 25.9 22.5 20.9 26.3 26.7 25.5 24.4 35.5 32.3 26.8 34.6 38.2 29.8 23.0 25.8 35.2 25.7 22.2 36.2 39.0 33.0 45.6 35.0 45.8 46.9 39.4 38.0 57.0 47.3 38.0 37.3 40.4 47.5 53.3 52.8 39.5 33.0 54.3 43.6 40.5 48.7 34.3 37.8 29.6 36.4 57.5 62.1 58.3 45.5 56.7 38.5 44.1 51.3 61.8 43.3 32.4 57.1 61.3 60.4 38.1 45.6 62.5 92.3 55.5 43.4 31.8 50.3 52.4 40.6 46.2 64.6 38.1 70.6 64.5 77.5 43.3 93.2 43.3 30.5 34.1 36.5 41.2 69.3 55.2 62.1 34.2 43.2 47.1 3.9 1.3 2.9 2.1 1.6 2.0 1.4 2.0 2.7 1.2 1.5 2.2 2.5 2.0 2.3 1.3 2.4 3.1 0.8 36.1 37.0 34.5 43.3 37.3 38.0 36.0 36.0 37.5 35.5 38.2 36.2 40.8 32.1 26.5 9.8 24.7 16.2 18.0 15.9 15.4 41.2 27.3 32.5 29.4 27.1 18.4 16.5 4.2 19.8 45.2 33.4 11.7 14.5 4.5 24.8 20.9 32.8 33.6 12.0 12.2 21.0 18.2 23.3 14.3 24.9 10.8 31.9 35.3 38.3 27.5 60.6 11.7 29.2 22.4 48.0 19.7 7.3 17.7 27.9 14.2 10.3 30.9 42.8 39.1 7.1 11.7 26.2 18.5 19.2 22.1 29.5 29.6 19.7 29.0 23.1 13.1 20.1 21.2 34.1 29.2 18.1 19.0 19.6 26.5 36.3 25.7 31.4 UBE2V2 "DDVit-1, DDVIT1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2" ENSG00000169139 "Ubiquitin conjugating enzyme E2 V2" Q15819 8 48008415-48064708 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052535, HPA053186" Supported Nucleoplasm NA NA 800000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA052535: AB_2681863, HPA053186: AB_2682073" "unprognostic (3.50e-3)" "unprognostic (3.27e-1)" "unprognostic (1.53e-1)" "unprognostic (3.07e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (2.94e-3)" "unprognostic (1.21e-2)" "unprognostic (1.65e-3)" "unprognostic (4.97e-2)" "unprognostic (1.77e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (4.96e-6)" "unprognostic (1.42e-1)" "unprognostic (1.42e-1)" "unprognostic (2.45e-1)" "unprognostic (9.62e-2)" 36.6 42.9 40.0 32.1 44.0 23.0 35.5 38.3 50.3 28.2 33.5 43.7 35.1 32.9 26.7 49.0 26.2 27.5 25.3 45.7 47.0 35.8 60.8 23.3 39.2 44.4 42.2 24.4 21.4 36.9 36.0 31.4 45.2 34.0 36.1 52.1 23.2 30.8 56.3 25.4 33.0 38.3 39.6 23.7 32.8 34.3 46.4 52.1 37.2 56.0 39.7 41.7 31.7 38.6 112.7 63.9 140.0 78.0 75.4 83.6 49.4 114.8 80.1 113.8 99.2 80.9 85.3 136.9 65.7 110.5 97.4 66.1 128.6 107.8 152.1 47.2 89.8 123.6 74.4 68.8 94.0 68.2 35.7 79.5 109.9 91.7 145.6 86.1 97.6 115.8 154.0 83.0 145.3 85.7 218.3 131.6 130.3 166.7 42.2 108.3 61.8 67.6 122.7 90.0 152.9 99.4 96.7 85.1 107.5 103.8 143.0 89.7 54.1 95.8 87.8 86.6 108.7 82.3 151.5 175.8 124.3 118.7 104.0 73.9 70.5 74.4 58.9 84.9 71.6 77.4 72.6 72.8 87.2 76.1 72.2 81.7 45.1 110.6 85.0 73.3 104.6 94.2 40.0 44.0 38.3 50.3 45.7 47.0 44.4 42.2 45.2 39.6 46.4 38.6 52.4 48.1 34.7 20.2 53.1 45.2 75.5 172.5 36.5 87.1 40.9 51.8 58.9 35.8 89.0 51.5 16.7 93.3 39.9 29.9 129.1 81.9 51.6 46.7 58.3 45.4 32.3 57.0 41.6 88.3 149.6 67.9 30.5 36.9 50.8 55.5 32.2 50.8 90.4 80.8 38.1 49.2 109.9 35.4 53.1 34.6 56.2 51.6 37.4 20.6 76.0 110.8 56.7 21.1 28.4 83.6 56.0 73.4 46.7 95.9 51.9 130.2 71.4 65.2 59.2 48.3 122.1 134.7 82.2 46.8 57.1 149.7 47.2 76.2 59.3 75.0 UBE3A "ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A" ENSG00000114062 "Ubiquitin protein ligase E3A" Q05086 15 25333728-25439051 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009723, HPA039410, HPA040380" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB009723: AB_639982, HPA039410: AB_10671997, HPA040380: AB_2676952" "unprognostic (7.95e-2)" "unprognostic (2.61e-2)" "unprognostic (1.58e-1)" "unprognostic (2.99e-1)" "unprognostic (1.13e-1)" "unprognostic (3.55e-2)" "unprognostic (1.44e-1)" "unprognostic (3.05e-1)" "unprognostic (5.07e-2)" "unprognostic (1.69e-1)" "unprognostic (3.40e-2)" "unprognostic (4.83e-2)" "unprognostic (6.31e-2)" "unprognostic (3.08e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (8.17e-2)" 29.1 29.0 28.0 27.6 30.3 32.4 32.6 42.8 41.7 33.5 14.0 33.5 22.9 32.9 29.5 32.9 29.9 24.5 40.6 31.0 28.2 32.6 42.2 24.9 33.3 22.3 23.6 37.1 27.2 38.4 15.3 28.4 24.0 31.8 28.9 32.8 23.3 28.4 109.2 26.8 29.5 30.9 19.9 26.9 26.1 45.6 28.1 41.7 41.5 92.0 34.2 32.8 20.0 29.2 55.9 33.6 77.7 46.1 45.0 56.4 38.4 84.8 54.8 59.9 55.6 76.0 27.6 103.4 61.2 68.2 57.8 51.2 106.8 62.2 75.2 54.1 32.7 85.8 49.0 43.1 65.5 107.0 60.2 60.6 56.2 58.3 71.6 60.0 47.6 87.0 89.0 71.1 95.1 32.3 84.0 29.1 50.3 62.1 46.6 88.6 117.8 45.6 51.7 91.1 80.0 59.6 72.1 72.1 102.1 51.3 57.9 56.7 59.2 102.1 84.7 52.1 64.5 77.5 103.4 139.5 60.4 56.6 55.3 14.4 12.7 17.2 17.0 11.2 19.9 17.3 18.5 20.8 16.7 22.8 20.8 18.7 2.2 29.6 22.3 15.2 15.8 9.7 28.0 30.3 42.8 41.7 31.0 28.2 22.3 23.6 24.0 19.9 28.1 29.2 56.6 96.1 80.5 112.6 74.7 71.1 83.8 40.6 84.2 82.7 59.5 42.3 175.3 42.9 58.7 38.6 56.3 52.3 74.3 43.3 19.6 51.6 139.4 53.6 75.2 58.7 68.7 64.3 187.7 49.6 49.6 64.1 52.5 63.8 62.8 84.1 44.3 58.6 46.0 80.8 196.3 55.0 12.2 60.9 41.1 61.6 56.8 64.4 53.4 87.1 53.3 54.5 54.6 126.2 124.4 59.8 41.5 64.7 95.7 102.8 51.4 50.3 59.4 59.2 78.9 119.0 80.5 146.1 88.3 78.3 90.6 74.0 63.3 65.7 52.6 98.6 UBFD1 "FLJ38870, FLJ42145, UBPH" ENSG00000103353 "Ubiquitin family domain containing 1" O14562 16 23557721-23574389 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.2" "Cell type enhanced" "Detected in many" "Late spermatids: 76.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051746 Approved Nucleoplasm,Nucleoli NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA051746: AB_2681587" "unprognostic (2.70e-2)" "unprognostic (1.84e-1)" "unprognostic (9.45e-3)" "unprognostic (2.31e-2)" "unprognostic (1.47e-1)" "unprognostic (4.91e-2)" "unprognostic (2.86e-3)" "unprognostic (1.63e-1)" "unprognostic (2.17e-1)" "unprognostic (3.86e-1)" "unprognostic (8.28e-2)" "unprognostic (8.06e-2)" "unprognostic (6.20e-3)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "unprognostic (3.13e-1)" "unprognostic (1.46e-1)" 12.8 20.7 18.8 11.9 18.3 10.8 12.7 16.6 19.0 13.7 25.0 13.6 7.4 17.1 18.3 13.1 17.3 12.0 20.7 18.4 24.3 15.5 17.0 9.9 12.4 20.1 21.2 17.4 13.5 25.2 19.6 18.0 26.2 15.4 11.7 10.7 12.4 15.2 81.2 10.6 9.6 18.8 16.5 11.1 10.7 26.0 21.9 21.0 17.7 39.0 15.7 13.4 11.1 16.7 17.1 40.0 55.0 40.0 62.3 76.9 48.8 45.8 44.2 42.3 39.1 29.9 30.1 39.3 68.5 66.9 28.5 23.6 88.4 36.1 53.9 57.1 47.3 20.8 34.0 66.3 33.2 21.9 34.7 55.1 26.5 41.3 38.4 64.9 41.4 31.1 47.6 20.7 47.1 37.4 30.9 39.5 118.0 29.2 17.2 53.6 33.7 33.0 39.5 14.9 53.5 47.6 17.6 34.3 31.8 52.7 47.1 31.6 43.1 23.3 26.1 25.7 27.2 25.0 29.8 23.6 43.0 25.3 36.6 0.0 0.5 0.5 1.4 0.7 0.7 0.6 0.9 1.3 1.1 1.3 0.5 0.8 0.0 1.2 0.3 1.5 0.8 0.4 18.8 18.3 16.6 19.0 18.4 24.3 20.1 21.2 26.2 16.5 21.9 16.7 10.0 6.4 2.6 10.1 6.8 8.8 10.2 10.3 13.1 11.6 16.5 13.8 35.1 8.6 6.6 20.2 22.9 19.2 14.9 8.1 15.6 13.0 49.3 20.7 29.4 11.6 7.2 10.3 14.6 11.5 27.2 17.2 7.1 20.6 0.0 26.4 5.3 19.0 13.4 6.7 12.3 10.2 2.0 6.6 5.1 76.1 18.6 6.6 10.6 7.5 10.7 11.0 6.2 5.0 9.8 8.8 8.9 9.8 9.8 20.4 4.8 18.3 8.8 14.9 26.3 17.1 19.2 21.3 21.7 14.0 14.2 36.0 8.3 22.2 9.3 14.8 UBL7 "BMSC-UbP, MGC14421" ENSG00000138629 "Ubiquitin like 7" Q96S82 15 74445977-74461182 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 175.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040423, HPA041897" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA040423: AB_10673442, HPA041897: AB_2677732" "unprognostic (4.21e-2)" "prognostic favorable (6.37e-5)" "unprognostic (2.93e-3)" "unprognostic (5.56e-2)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "unprognostic (3.43e-2)" "unprognostic (1.29e-1)" "unprognostic (1.80e-1)" "unprognostic (6.71e-2)" "unprognostic (5.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.47e-3)" "unprognostic (8.94e-3)" "unprognostic (7.05e-2)" "unprognostic (2.75e-1)" "unprognostic (3.43e-2)" 33.8 38.4 27.0 13.5 28.9 15.9 32.9 26.7 35.0 34.0 23.9 48.1 15.0 36.8 15.4 37.8 30.3 10.6 67.9 29.4 26.9 38.1 32.0 29.7 21.4 28.2 27.3 31.1 44.7 25.0 30.3 15.6 29.2 36.4 16.5 13.1 34.2 16.3 114.6 54.3 36.9 18.4 25.5 48.2 43.5 55.8 25.9 27.3 37.0 37.8 29.6 38.7 33.1 29.0 18.7 20.3 31.6 42.3 32.4 42.1 21.8 29.8 36.0 37.6 46.6 24.7 26.4 27.2 31.1 35.9 48.6 29.4 88.4 40.4 36.5 36.0 55.6 35.8 32.2 45.3 31.7 22.4 29.1 32.9 35.5 32.1 43.0 32.3 32.0 60.8 30.9 39.3 39.3 26.2 28.1 35.3 75.7 31.2 24.6 29.4 25.0 60.5 32.6 21.2 31.1 61.8 28.8 26.8 40.1 44.1 28.6 36.7 18.8 34.6 20.4 17.4 37.5 39.8 82.1 30.5 22.7 40.3 30.6 32.9 51.6 59.7 35.1 58.5 33.7 50.5 35.3 37.1 70.6 55.3 33.9 40.6 65.3 55.5 55.5 151.5 65.6 52.1 27.0 28.9 26.7 35.0 29.4 26.9 28.2 27.3 29.2 25.5 25.9 29.0 17.3 32.1 18.2 3.9 35.4 15.8 24.1 35.6 26.7 5.8 24.9 23.9 29.9 18.6 20.0 14.7 8.4 71.1 36.8 25.5 58.7 37.3 75.3 12.7 13.0 20.7 23.4 45.8 5.7 34.7 66.9 20.7 22.4 13.5 19.0 21.5 22.5 16.3 41.9 5.0 3.8 26.9 20.3 38.3 31.4 175.8 24.5 31.4 21.4 5.6 82.6 18.2 23.7 4.0 4.5 29.5 27.6 21.1 51.6 19.5 48.9 44.6 16.1 9.0 19.7 13.5 50.5 59.2 31.1 29.8 25.1 68.4 23.0 19.6 28.0 25.2 UBN2 "FLJ25778, KIAA2030" ENSG00000157741 "Ubinuclein 2" Q6ZU65 7 139230356-139308236 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 140.7;Late spermatids: 178.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "basophil: 8.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 8.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019743, HPA020122, HPA020124" Uncertain Enhanced Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA019743: AB_1848851, HPA020122: AB_1848847, HPA020124: AB_2212202" "unprognostic (1.96e-1)" "unprognostic (2.49e-1)" "unprognostic (2.48e-2)" "unprognostic (1.44e-2)" "unprognostic (2.41e-1)" "prognostic favorable (4.49e-4)" "unprognostic (1.24e-3)" "unprognostic (1.22e-2)" "unprognostic (1.30e-3)" "unprognostic (9.88e-2)" "unprognostic (1.65e-1)" "unprognostic (4.96e-2)" "unprognostic (3.65e-2)" "unprognostic (4.54e-3)" "unprognostic (2.95e-1)" "unprognostic (2.91e-2)" "unprognostic (1.05e-2)" 3.4 4.6 4.2 2.4 2.9 5.9 4.7 12.2 5.9 5.6 2.0 4.2 2.4 4.7 6.8 4.3 5.3 2.7 3.8 3.4 5.0 3.4 4.4 3.6 2.6 1.8 1.7 6.2 6.6 4.0 8.4 3.0 1.1 4.6 3.3 13.5 5.0 3.0 7.3 9.7 3.8 3.0 0.1 3.5 3.9 14.5 2.5 3.3 5.8 4.8 2.5 4.1 5.1 8.0 3.3 3.1 4.9 6.1 3.8 3.5 3.7 1.8 2.7 1.6 2.0 3.7 3.2 5.5 3.4 2.3 4.2 3.0 6.3 1.5 2.9 2.8 3.7 4.2 5.8 4.1 2.2 8.2 3.1 2.4 4.3 2.2 3.4 3.0 3.3 2.9 9.9 4.1 2.1 5.0 5.9 9.4 6.9 3.3 2.2 3.4 4.6 3.9 2.3 2.4 8.0 5.8 5.7 3.9 2.7 4.5 2.5 5.4 3.7 2.0 2.3 3.1 2.4 4.8 5.8 9.5 3.4 4.9 3.0 8.5 0.6 0.0 0.3 0.2 0.2 0.5 0.3 0.3 0.2 0.6 0.4 0.3 0.5 1.9 0.2 0.7 0.2 0.1 4.2 2.9 12.2 5.9 3.4 5.0 1.8 1.7 1.1 0.1 2.5 8.0 21.0 6.4 23.6 58.1 11.7 23.3 18.6 9.9 15.4 54.0 23.2 13.6 27.2 21.5 15.0 22.0 93.8 9.0 21.8 16.5 7.9 8.0 140.7 58.3 38.2 17.7 23.4 24.8 97.5 6.9 8.9 20.2 14.3 68.8 11.4 28.7 17.5 22.6 7.1 45.4 95.1 16.7 10.2 11.5 17.9 178.6 22.4 15.4 8.8 53.4 19.0 23.6 16.5 79.4 84.9 9.2 14.0 21.4 16.2 41.5 15.7 11.0 36.5 58.2 19.7 37.6 22.8 44.6 31.6 20.9 28.8 14.6 14.3 27.2 13.5 28.4 UBQLN1 "DA41, DSK2, PLIC-1, XDRP1" ENSG00000135018 "Ubiquilin 1" Q9UMX0 9 83659968-83707958 "Plasma proteins, Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037256, HPA054143" Supported Supported Nucleoplasm,Cytosol NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB037256: AB_1858556, HPA054143: AB_2682398" "unprognostic (4.72e-3)" "unprognostic (9.61e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-1)" "unprognostic (2.77e-2)" "unprognostic (2.87e-2)" "unprognostic (1.55e-1)" "unprognostic (2.80e-3)" "unprognostic (2.35e-1)" "unprognostic (1.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.07e-5)" "unprognostic (3.11e-2)" "unprognostic (9.49e-2)" "unprognostic (1.44e-3)" "unprognostic (2.29e-2)" 50.1 49.8 43.0 43.6 46.4 84.9 42.3 42.2 46.7 40.7 30.6 44.2 39.3 43.1 38.8 50.8 36.9 37.0 63.0 50.1 50.2 55.2 74.0 39.0 51.1 46.7 47.2 36.1 50.5 72.2 28.6 50.4 50.7 45.4 41.3 55.8 34.5 46.8 125.8 42.4 39.6 47.1 43.6 37.7 42.4 42.0 46.3 69.4 45.3 72.9 65.1 53.3 35.2 57.0 154.5 137.8 101.9 77.9 83.4 89.3 164.0 140.8 125.4 147.7 111.3 56.8 105.5 153.9 86.6 120.0 137.0 172.0 141.8 101.7 152.7 79.7 66.0 95.1 97.9 90.3 111.7 116.6 98.3 74.7 127.1 124.1 172.4 92.8 112.8 72.6 102.7 105.7 124.6 91.0 160.8 66.6 132.6 147.5 126.3 117.6 113.7 80.4 98.7 65.0 90.4 101.2 130.9 131.7 102.0 100.2 64.6 84.2 111.8 92.2 84.9 154.2 143.6 146.1 222.0 74.7 139.4 85.1 114.1 34.9 21.2 22.6 19.8 31.4 19.3 19.0 16.9 18.2 24.2 19.6 16.9 18.5 22.7 31.8 30.7 10.5 24.2 20.5 43.0 46.4 42.2 46.7 50.1 50.2 46.7 47.2 50.7 43.6 46.3 57.0 39.5 35.3 42.2 29.4 53.9 103.2 66.2 43.0 42.7 58.4 41.2 28.3 76.7 31.5 46.8 22.0 20.9 59.9 38.9 49.9 19.6 55.1 37.9 47.7 50.9 42.8 51.4 51.8 61.9 53.5 86.9 42.2 32.1 74.9 50.1 33.6 25.7 73.4 52.1 75.7 58.7 41.5 42.7 51.2 87.5 18.3 24.5 52.4 42.7 41.2 46.5 31.0 39.1 33.2 67.9 70.4 36.5 27.8 56.2 68.8 48.9 39.6 33.4 34.1 39.5 33.4 42.9 74.1 50.5 45.2 92.5 164.3 47.7 28.9 41.1 84.0 UBTF "NOR-90, UBF, UBF1, UBF2" ENSG00000108312 "Upstream binding transcription factor" P17480 17 44205033-44221626 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004611, HPA006385" Supported Supported Enhanced "Nucleoli fibrillar center" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli fibrillar center" "CAB004611: AB_671403, HPA006385: AB_1080447" "unprognostic (1.37e-3)" "unprognostic (1.12e-3)" "unprognostic (2.54e-1)" "unprognostic (1.12e-2)" "unprognostic (3.15e-1)" "unprognostic (8.54e-3)" "unprognostic (1.35e-3)" "unprognostic (4.10e-2)" "unprognostic (5.39e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-2)" "unprognostic (2.10e-1)" "unprognostic (1.96e-3)" "unprognostic (5.44e-2)" "unprognostic (9.01e-2)" "unprognostic (1.91e-2)" "unprognostic (2.00e-1)" 34.8 36.5 36.2 44.8 33.7 54.9 35.4 38.2 37.1 50.6 30.1 49.4 33.6 50.8 27.5 41.8 41.9 32.5 38.8 35.5 32.7 38.1 36.1 32.3 67.6 34.0 34.5 41.6 41.4 38.2 33.8 29.2 32.2 41.6 28.2 23.1 37.7 40.8 63.7 47.4 42.5 36.3 31.6 49.8 34.7 20.8 34.9 73.6 46.4 36.6 51.7 45.1 41.8 35.0 69.1 104.3 77.3 93.2 49.6 56.5 72.3 70.6 46.7 70.1 52.0 50.7 54.8 250.0 69.3 65.3 51.9 63.6 99.1 59.2 57.9 145.3 109.5 100.5 73.8 83.7 32.5 192.1 85.7 56.9 52.2 44.6 65.6 67.2 58.9 108.8 117.4 75.9 58.9 113.7 188.3 75.0 73.7 46.6 81.6 184.0 104.3 112.0 40.4 54.5 119.5 90.3 70.4 62.2 54.2 47.9 89.9 120.8 75.5 109.9 133.1 65.1 95.0 66.6 61.7 151.1 64.8 86.0 100.1 9.6 5.7 6.1 15.5 6.3 16.7 11.7 10.8 16.2 6.7 14.1 12.2 13.1 9.7 15.7 11.6 12.7 10.0 11.3 36.2 33.7 38.2 37.1 35.5 32.7 34.0 34.5 32.2 31.6 34.9 35.0 41.4 41.7 42.1 14.7 57.5 20.5 19.6 17.9 57.5 88.8 31.0 29.6 44.5 35.8 32.2 38.6 79.2 30.9 60.3 41.7 35.2 27.2 2.3 39.3 57.7 42.7 47.3 61.2 8.5 40.8 40.7 38.9 23.9 48.1 31.7 43.1 32.5 26.5 25.9 26.9 8.2 32.5 12.2 18.4 13.3 3.6 36.7 27.4 23.2 8.4 38.1 33.9 54.6 3.5 10.6 28.1 30.7 50.8 42.2 17.4 26.7 25.4 26.5 57.6 52.6 48.5 45.9 5.3 44.0 52.1 24.3 32.7 53.1 40.2 32.8 11.8 UCHL3 ENSG00000118939 "Ubiquitin C-terminal hydrolase L3" P15374 13 75549480-75606020 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019678, CAB037139, CAB037208" Approved Supported Nucleoplasm,Cytosol No No 700000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "CAB037139: AB_1841234, CAB037208: AB_1841235, HPA019678: AB_1858583" "unprognostic (4.16e-1)" "unprognostic (3.84e-2)" "unprognostic (8.83e-3)" "unprognostic (1.14e-1)" "unprognostic (5.15e-2)" "unprognostic (6.46e-3)" "prognostic unfavorable (6.41e-4)" "unprognostic (1.19e-1)" "unprognostic (5.59e-2)" "unprognostic (9.71e-2)" "unprognostic (1.24e-1)" "unprognostic (7.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.97e-1)" "unprognostic (2.76e-2)" "unprognostic (8.84e-2)" "unprognostic (3.26e-2)" 20.7 56.9 20.6 20.2 24.2 33.5 34.2 20.3 25.2 15.3 17.2 35.4 21.6 12.4 63.2 58.0 13.0 17.7 29.3 21.7 20.5 32.2 50.9 15.0 21.3 18.6 18.9 7.4 30.9 23.9 22.9 24.6 18.5 19.5 39.5 9.7 27.2 18.2 53.9 48.6 19.9 25.1 18.9 15.9 25.1 43.3 20.5 25.7 44.4 40.6 34.6 44.3 26.6 21.0 196.0 31.9 26.9 18.8 49.9 58.6 78.6 72.3 70.3 90.7 100.5 177.5 92.1 100.4 50.2 75.7 70.2 105.8 64.1 175.3 137.1 53.8 55.9 62.2 50.7 114.9 71.6 150.4 45.7 52.6 118.7 71.7 114.2 38.4 90.1 79.6 70.0 27.9 138.9 70.2 62.4 100.2 40.3 229.0 95.1 49.5 42.9 66.3 108.4 77.9 81.0 23.8 40.8 78.3 34.5 58.2 45.7 42.0 70.8 39.6 47.9 42.7 98.2 39.5 45.5 117.1 80.4 161.3 29.0 57.6 68.7 49.3 29.9 134.4 39.6 51.5 54.1 43.0 99.5 51.5 53.0 49.5 15.6 62.7 117.9 134.9 71.8 50.1 20.6 24.2 20.3 25.2 21.7 20.5 18.6 18.9 18.5 18.9 20.5 21.0 18.2 9.6 23.4 9.1 20.3 76.3 80.4 197.5 35.9 9.3 48.8 66.2 27.2 28.6 88.2 46.0 2.1 105.2 32.9 39.0 92.0 146.2 198.2 35.4 17.4 26.6 24.0 24.4 22.5 143.1 163.6 25.1 23.9 36.2 24.1 19.3 13.9 45.7 88.0 16.8 22.3 54.6 81.4 28.8 28.8 43.5 16.8 32.8 26.6 18.7 33.3 17.3 22.6 22.6 24.9 153.1 44.3 11.7 33.3 133.1 40.4 119.6 48.0 8.9 19.7 24.5 73.5 159.3 36.8 64.8 79.1 169.0 22.1 47.6 60.8 96.2 UQCC2 "bA6B20.2, C6orf125, Cbp6, M19, MGC14833, MNF1" ENSG00000137288 "Ubiquinol-cytochrome c reductase complex assembly factor 2" Q9BRT2 6 33694293-33711727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 911.7;Late spermatids: 1207.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039111 Uncertain Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 38: Heart - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "Nuclear bodies" "HPA039111: AB_2676352" "unprognostic (3.58e-2)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (1.93e-1)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (3.21e-2)" "unprognostic (1.50e-1)" "unprognostic (2.35e-3)" "unprognostic (2.43e-2)" "unprognostic (5.93e-2)" "unprognostic (2.33e-2)" "unprognostic (7.43e-2)" "unprognostic (5.77e-2)" "unprognostic (3.88e-1)" "unprognostic (1.07e-1)" 38.9 69.6 100.5 37.3 102.8 45.3 45.3 103.3 140.9 48.4 97.6 43.3 34.3 61.5 58.4 59.2 40.0 20.8 267.2 100.1 106.6 66.9 83.3 33.9 35.6 102.5 102.2 33.4 61.2 46.8 78.0 29.3 102.9 55.4 44.0 104.3 53.0 28.6 228.8 42.9 28.5 52.4 102.4 43.2 49.5 104.1 104.4 45.7 42.9 197.9 40.8 46.1 42.8 107.9 207.7 144.2 162.8 139.4 130.9 129.8 125.5 116.4 117.3 167.7 162.6 233.9 84.5 84.4 180.3 143.5 244.1 109.0 111.7 164.5 138.6 108.0 187.7 163.3 87.3 327.6 215.9 153.8 127.2 136.2 257.4 131.7 204.7 91.0 120.4 158.9 178.4 165.9 190.4 220.9 149.0 315.9 97.3 158.4 167.6 106.5 130.7 279.9 116.2 191.5 273.1 97.1 127.9 191.7 165.6 84.1 168.3 382.2 110.5 178.0 151.1 115.9 242.0 126.8 193.1 146.6 53.7 229.7 211.0 32.7 88.5 18.2 76.1 141.6 93.6 152.4 95.0 87.6 108.6 116.1 98.7 88.0 8.4 81.6 120.9 133.2 110.7 123.8 100.5 102.8 103.3 140.9 100.1 106.6 102.5 102.2 102.9 102.4 104.4 107.9 18.5 28.9 29.3 8.1 54.2 58.5 96.8 193.0 61.5 108.7 96.0 100.3 911.7 74.4 119.8 77.3 50.1 134.7 34.0 112.4 391.3 103.4 342.3 46.6 78.7 54.1 99.7 105.0 8.9 179.7 124.4 88.5 90.7 39.1 59.5 90.0 41.4 166.1 218.8 70.7 10.2 94.5 154.6 67.8 55.6 1207.0 78.6 64.8 83.6 3.7 63.6 79.1 46.4 9.0 10.0 95.6 64.2 83.8 88.3 122.1 44.6 257.2 87.1 123.8 0.0 32.9 269.4 155.9 96.0 103.3 76.3 95.4 43.5 159.3 102.3 118.5 USE1 "D12, MDS032, p31, SLT1" ENSG00000053501 "Unconventional SNARE in the ER 1" Q9NZ43 19 17215346-17219829 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026851, HPA047562" Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 10: Non-specific - Unknown function" "HPA026851: AB_10602903, HPA047562: AB_2680089" "unprognostic (3.03e-3)" "unprognostic (2.61e-3)" "unprognostic (2.24e-2)" "unprognostic (3.09e-2)" "unprognostic (1.03e-1)" "unprognostic (2.34e-1)" "unprognostic (2.00e-1)" "unprognostic (3.04e-2)" "unprognostic (4.24e-1)" "unprognostic (2.94e-2)" "unprognostic (1.15e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.59e-4)" "unprognostic (8.14e-2)" "unprognostic (3.23e-1)" "unprognostic (6.61e-2)" "unprognostic (1.31e-2)" 33.2 40.2 48.0 20.2 50.0 28.8 30.5 48.1 57.9 30.7 45.2 30.5 17.4 24.5 19.0 25.9 24.0 20.2 47.1 48.4 49.0 31.6 42.0 25.7 28.2 49.8 49.0 31.9 43.2 14.2 22.1 15.6 49.3 26.8 10.9 11.8 38.4 14.9 56.0 28.2 25.4 14.9 48.2 39.7 31.7 19.6 48.0 25.2 24.6 36.2 18.3 29.3 24.4 53.8 34.5 20.1 10.9 45.4 36.4 34.4 37.7 24.5 28.3 27.0 33.7 26.4 40.4 23.0 55.5 33.6 9.5 19.6 9.7 33.4 9.3 49.5 44.2 42.5 37.6 28.3 74.4 47.9 37.7 47.2 17.6 23.4 46.3 30.7 18.1 55.8 27.6 77.8 28.5 41.3 46.2 35.2 21.2 26.6 70.1 36.2 12.1 89.6 31.4 27.5 29.4 25.9 27.1 39.1 42.5 10.9 25.2 74.5 26.6 17.8 17.2 32.5 30.9 87.4 86.7 30.9 47.9 76.2 30.2 43.9 58.1 18.0 54.3 51.6 61.8 139.4 80.9 65.8 71.5 128.9 115.6 86.4 10.5 54.4 38.8 87.0 85.0 66.6 48.0 50.0 48.1 57.9 48.4 49.0 49.8 49.0 49.3 48.2 48.0 53.8 34.0 32.1 27.2 6.8 48.8 45.2 53.0 48.5 44.3 24.5 48.4 58.8 45.0 30.0 30.0 16.5 18.8 45.0 32.4 47.2 72.4 37.4 39.5 20.3 35.0 28.4 13.8 19.6 9.2 62.0 35.1 37.3 32.6 24.9 48.9 35.3 34.6 48.4 40.7 11.8 8.1 35.0 26.4 39.0 29.2 137.4 48.1 29.9 21.4 3.7 33.5 41.5 28.8 17.1 12.1 31.2 53.7 26.7 34.1 38.5 51.2 118.2 22.7 34.7 39.5 39.2 62.9 20.7 25.5 29.5 34.8 75.7 36.8 42.4 31.8 38.9 USP19 "KIAA0891, ZMYND9" ENSG00000172046 "Ubiquitin specific peptidase 19" O94966 3 49108046-49120938 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" "unprognostic (3.23e-2)" "unprognostic (2.12e-1)" "unprognostic (5.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-2)" "unprognostic (3.90e-3)" "unprognostic (2.99e-2)" "unprognostic (3.00e-3)" "unprognostic (2.69e-1)" "unprognostic (3.65e-2)" "unprognostic (2.31e-2)" "unprognostic (1.26e-1)" "prognostic favorable (7.05e-9)" "unprognostic (2.99e-1)" "unprognostic (2.11e-1)" "unprognostic (1.72e-3)" "unprognostic (7.54e-2)" 20.3 25.5 16.4 19.4 18.7 26.8 19.6 19.0 18.6 21.9 24.4 26.2 22.4 24.3 19.1 19.7 24.3 15.5 26.8 17.4 16.8 18.9 18.6 17.7 21.5 19.0 17.5 22.8 21.2 31.0 17.5 16.5 17.9 19.4 15.9 14.3 29.6 24.4 75.6 26.5 21.9 18.9 16.7 22.9 21.6 20.8 18.4 27.4 23.6 45.0 16.8 23.3 19.6 19.5 20.2 26.3 28.6 42.1 36.8 24.1 38.7 23.1 26.1 35.1 28.7 28.7 27.3 41.6 22.2 24.4 36.2 24.1 40.3 29.1 16.0 32.7 32.1 42.5 56.4 22.8 36.1 45.7 40.5 33.8 22.7 36.9 24.1 25.9 24.2 33.8 30.8 28.4 18.9 23.9 42.6 43.0 58.2 27.4 44.1 19.4 24.3 45.7 22.3 37.4 16.5 51.4 33.3 38.1 34.9 26.1 26.0 55.4 21.8 24.5 30.5 36.7 33.7 77.7 97.1 38.0 32.8 34.3 32.6 9.7 3.7 5.3 4.5 3.6 4.2 2.8 3.7 5.2 4.6 2.9 3.3 3.9 7.5 2.9 4.4 1.9 2.7 4.3 16.4 18.7 19.0 18.6 17.4 16.8 19.0 17.5 17.9 16.7 18.4 19.5 7.8 12.8 14.5 10.4 7.2 6.2 3.8 8.5 8.6 12.7 8.7 7.4 13.1 5.7 9.9 7.3 18.8 9.6 9.2 17.1 5.9 7.7 3.6 14.8 8.7 7.6 9.1 10.3 8.4 7.8 5.3 7.7 14.3 9.5 2.5 8.1 7.9 13.6 9.0 13.5 8.0 11.6 10.2 8.7 4.7 4.9 13.1 6.8 3.6 2.8 6.5 8.7 3.1 8.0 7.7 11.5 13.9 12.4 7.4 4.2 16.3 7.7 14.9 11.4 13.1 12.3 11.1 16.2 13.2 9.1 5.4 13.5 8.0 9.8 13.4 3.1 UTP15 "FLJ12787, FLJ23637, NET21" ENSG00000164338 "UTP15 small subunit processome component" Q8TED0 5 73565443-73583380 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 36.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044697 Approved "Nucleoli,Endoplasmic reticulum" No No "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Endoplasmic reticulum" "HPA044697: AB_2679050" "unprognostic (8.96e-2)" "unprognostic (1.19e-1)" "unprognostic (1.87e-3)" "unprognostic (8.36e-2)" "unprognostic (1.78e-1)" "unprognostic (5.80e-2)" "unprognostic (1.39e-2)" "unprognostic (5.74e-2)" "unprognostic (2.12e-1)" "unprognostic (4.16e-3)" "unprognostic (1.02e-1)" "unprognostic (1.53e-2)" "unprognostic (2.27e-2)" "unprognostic (9.66e-2)" "unprognostic (7.10e-2)" "unprognostic (1.92e-1)" "unprognostic (1.22e-1)" 8.7 6.5 2.0 8.0 2.4 36.9 9.7 3.2 3.2 4.6 1.2 6.8 5.5 7.2 6.4 9.2 5.0 5.1 4.8 2.2 2.5 5.1 7.5 5.9 10.8 2.1 2.3 4.9 7.4 7.5 3.1 6.0 2.7 5.9 8.3 5.5 4.9 4.7 7.2 9.5 5.2 7.6 1.6 7.8 5.7 6.1 2.1 7.6 8.1 7.5 10.7 9.3 4.5 3.6 21.2 22.3 15.8 44.6 12.6 14.9 27.9 24.8 14.1 27.1 29.8 25.0 29.6 47.5 24.9 16.6 34.2 17.3 25.5 45.5 41.6 23.9 19.2 21.7 23.7 20.2 15.5 20.2 18.1 15.2 20.0 30.8 34.3 8.3 19.1 21.2 33.8 25.3 23.2 26.4 31.7 14.0 20.6 7.5 12.7 24.5 24.7 45.9 16.1 28.5 15.8 16.9 22.7 17.6 27.4 13.4 22.8 14.4 15.4 15.9 22.5 19.4 49.3 19.0 27.6 60.5 26.0 34.3 23.8 4.9 6.8 4.6 8.2 7.0 7.6 7.9 8.1 9.1 7.4 7.0 9.6 9.4 5.1 8.2 7.2 7.0 7.3 4.9 2.0 2.4 3.2 3.2 2.2 2.5 2.1 2.3 2.7 1.6 2.1 3.6 8.4 0.0 7.3 2.3 7.7 14.7 13.1 5.0 11.4 3.8 6.7 6.5 6.8 4.3 5.2 5.5 6.2 8.0 6.0 2.7 3.9 8.9 4.3 4.9 6.8 6.9 2.4 9.4 6.4 7.8 9.5 8.0 5.6 6.8 7.0 6.7 2.9 8.1 6.8 1.7 5.4 4.1 2.0 5.8 2.1 2.8 3.1 3.9 7.2 1.9 3.6 3.0 2.1 3.5 6.9 6.5 3.6 5.3 9.1 10.0 2.2 6.3 1.7 4.7 6.6 9.5 8.8 10.0 12.4 11.7 17.0 6.6 6.1 7.6 6.7 9.8 UTP18 "CGI-48, WDR50" ENSG00000011260 "UTP18 small subunit processome component" Q9Y5J1 17 51260546-51297936 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 190.6;Late spermatids: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052378 Approved Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nucleoli rim" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear membrane" "HPA052378: AB_2681805" "unprognostic (1.36e-2)" "unprognostic (1.00e-1)" "prognostic favorable (3.33e-4)" "unprognostic (2.62e-2)" "unprognostic (2.55e-2)" "unprognostic (5.99e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (2.47e-2)" "unprognostic (8.37e-3)" "unprognostic (1.10e-2)" "unprognostic (8.82e-2)" "unprognostic (2.75e-2)" "unprognostic (3.11e-3)" "unprognostic (9.51e-2)" "unprognostic (1.59e-1)" "unprognostic (8.72e-3)" "unprognostic (1.93e-2)" 17.9 20.1 12.6 24.9 13.7 40.0 25.8 19.1 15.7 18.8 14.2 17.5 17.8 15.7 15.8 21.0 17.5 12.8 10.2 13.2 13.8 21.8 22.3 17.3 33.1 13.0 12.3 23.8 21.3 23.3 20.4 26.3 13.6 16.2 18.7 17.5 17.4 14.2 24.4 32.3 16.5 12.9 13.0 24.5 18.1 58.7 13.2 27.7 24.4 16.2 34.4 24.8 18.0 15.6 90.5 87.7 54.6 50.3 35.1 52.2 142.2 48.9 40.2 83.5 79.7 55.4 49.3 113.5 67.8 36.6 89.0 48.1 89.7 52.0 123.3 74.8 117.0 119.4 52.6 97.3 48.0 127.9 56.4 33.9 39.5 71.1 57.0 42.1 50.7 55.6 98.7 50.6 63.5 56.1 115.6 86.9 78.5 127.5 91.8 103.2 124.2 89.4 61.3 59.1 60.7 76.9 56.7 66.6 114.7 67.4 82.3 64.4 44.7 85.3 71.8 71.1 102.9 97.4 192.5 131.5 53.0 87.6 62.4 19.0 48.2 27.9 40.2 46.9 49.9 54.1 50.7 49.2 55.9 52.4 53.6 51.1 8.2 40.0 49.0 35.0 56.8 56.2 12.6 13.7 19.1 15.7 13.2 13.8 13.0 12.3 13.6 13.0 13.2 15.6 20.6 16.0 23.4 11.8 37.4 60.2 62.9 40.6 33.0 15.6 19.6 17.9 4.4 20.0 25.2 14.7 14.6 66.7 27.4 11.4 39.2 38.4 190.6 26.3 27.3 25.1 16.1 20.8 18.5 46.9 71.2 24.5 14.3 24.1 31.7 19.6 8.9 17.1 62.8 10.1 18.0 20.7 34.6 37.7 26.1 182.0 26.8 33.3 23.2 15.0 42.2 21.3 25.7 17.6 24.6 34.2 16.3 22.2 24.2 50.2 13.8 37.5 38.8 11.8 13.1 24.8 35.7 140.2 104.5 27.7 52.7 79.6 30.4 30.8 25.3 48.1 UTP3 "CRLZ1, DKFZp761F222, FLJ23256, SAS10" ENSG00000132467 "UTP3 small subunit processome component" Q9NQZ2 4 70688532-70690551 "Predicted intracellular proteins" "Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035655, HPA041453" Approved Supported Nucleoli,Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoli Vesicles "HPA035655: AB_10601832, HPA041453: AB_2677488" "unprognostic (2.44e-2)" "unprognostic (9.70e-2)" "unprognostic (7.36e-3)" "unprognostic (2.72e-2)" "unprognostic (1.15e-1)" "unprognostic (1.90e-2)" "unprognostic (6.79e-3)" "unprognostic (2.13e-1)" "unprognostic (3.50e-2)" "unprognostic (1.66e-1)" "unprognostic (1.53e-1)" "unprognostic (4.44e-3)" "prognostic favorable (3.16e-4)" "unprognostic (4.45e-2)" "unprognostic (7.95e-2)" "unprognostic (2.24e-1)" "unprognostic (2.24e-2)" 22.4 22.7 8.9 25.5 9.5 19.1 18.7 9.4 11.3 14.0 10.0 16.9 16.3 16.1 15.0 20.6 16.3 14.6 17.0 9.9 9.8 21.0 27.1 18.6 33.0 9.1 9.3 15.7 14.9 16.3 9.4 16.3 9.1 15.1 16.4 12.0 15.9 13.7 15.9 18.8 21.5 20.2 8.7 34.5 17.8 11.4 9.6 32.1 16.0 13.1 31.5 22.1 12.3 10.0 33.7 32.3 42.4 35.4 58.9 44.3 36.3 68.4 43.9 38.4 37.0 42.4 43.7 147.4 42.1 58.9 43.8 27.7 62.7 93.7 55.4 45.9 35.9 56.1 43.0 45.9 63.9 85.9 47.9 60.4 55.2 47.0 46.0 42.3 52.2 42.3 65.3 48.2 62.8 69.7 79.9 47.8 29.6 68.9 46.7 33.8 58.3 60.5 69.7 53.7 35.5 48.4 29.1 65.4 44.5 46.1 36.1 34.2 58.5 38.8 65.9 37.3 44.3 69.6 55.4 104.8 47.3 41.4 34.8 8.4 10.7 5.6 6.4 12.6 6.8 7.0 5.3 7.4 13.4 6.1 7.7 6.7 0.8 6.8 11.3 13.5 7.3 5.5 8.9 9.5 9.4 11.3 9.9 9.8 9.1 9.3 9.1 8.7 9.6 10.0 19.2 57.7 54.2 4.9 23.7 22.9 44.3 42.2 24.5 19.4 12.3 14.4 20.6 14.3 50.5 12.9 6.2 26.7 30.0 11.8 19.6 29.3 1.1 22.8 29.3 26.7 15.0 16.8 6.2 29.8 14.6 23.6 21.9 25.1 29.2 16.7 16.8 25.1 21.9 16.8 5.9 14.7 30.5 37.8 24.2 2.2 17.4 24.2 12.4 5.6 27.9 26.8 30.9 2.5 8.9 22.6 9.5 25.2 18.5 23.0 15.9 27.9 45.7 22.3 13.1 30.8 48.8 11.5 9.5 23.0 25.6 21.6 24.6 22.2 15.6 29.9 VAPA "hVAP-33, VAP-A" ENSG00000101558 "VAMP associated protein A" Q9P0L0 18 9914016-9960021 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009174 Approved Enhanced "Endoplasmic reticulum" NA NA 580000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA009174: AB_1080549" "unprognostic (4.03e-2)" "unprognostic (7.47e-2)" "unprognostic (9.36e-2)" "unprognostic (5.20e-2)" "unprognostic (2.00e-1)" "unprognostic (2.99e-2)" "unprognostic (4.79e-3)" "unprognostic (1.80e-1)" "unprognostic (5.39e-2)" "unprognostic (6.80e-3)" "unprognostic (2.99e-2)" "unprognostic (8.11e-2)" "prognostic favorable (5.72e-7)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.23e-1)" "unprognostic (5.77e-2)" 33.1 67.1 21.5 24.2 26.8 97.1 29.5 30.7 28.1 30.2 21.5 38.6 31.2 32.9 24.8 47.5 29.3 31.9 37.5 23.2 24.9 32.6 36.6 33.9 25.7 34.9 26.3 39.1 40.9 36.2 17.7 29.8 34.5 24.5 35.4 20.1 32.6 22.0 69.7 32.3 30.6 27.4 27.8 26.7 38.9 29.1 25.5 30.0 35.2 38.4 26.3 36.5 32.2 30.7 58.1 34.4 40.7 26.7 46.9 50.5 56.8 69.9 57.9 62.3 67.9 46.6 55.9 56.5 63.6 61.5 53.9 39.7 39.8 66.7 70.7 35.6 49.8 92.4 33.8 72.3 110.8 126.3 169.7 47.8 66.3 59.0 69.6 48.7 64.0 45.4 94.6 57.3 55.2 31.2 97.4 72.9 26.2 197.6 54.3 50.4 55.2 77.5 60.9 57.3 57.2 31.2 81.1 48.7 53.2 37.2 45.7 64.2 68.9 100.7 75.3 105.6 86.3 101.9 89.2 66.6 57.0 53.5 70.8 131.3 143.3 251.0 69.8 127.9 82.9 100.0 72.1 75.4 118.1 94.4 78.1 72.1 226.2 90.8 109.5 84.6 98.9 183.9 21.5 26.8 30.7 28.1 23.2 24.9 34.9 26.3 34.5 27.8 25.5 30.7 173.6 128.2 178.8 63.0 160.0 673.4 358.4 356.5 278.3 113.9 248.2 179.3 218.3 167.3 229.4 207.8 62.6 296.9 148.0 427.2 457.8 291.8 10.5 235.9 182.2 232.4 144.6 188.1 91.4 361.3 321.6 221.4 156.0 255.8 225.2 220.2 211.3 141.1 287.8 136.3 93.2 180.6 390.6 288.2 459.8 21.7 182.0 285.9 279.3 63.7 350.4 124.3 108.1 102.1 150.4 310.2 262.7 216.3 146.6 335.4 255.9 390.4 265.5 79.5 190.7 204.8 371.4 231.3 201.4 267.3 622.5 452.6 190.2 253.6 201.0 390.8 VCPIP1 "DUBA3, FLJ23132, KIAA1850, VCIP135" ENSG00000175073 "Valosin containing protein interacting protein 1" Q96JH7 8 66628487-66667231 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 20.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023932 Uncertain Approved "Plasma membrane,Centrosome" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" Centrosome "HPA023932: AB_2671373" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (4.01e-2)" "unprognostic (5.56e-2)" "unprognostic (5.23e-2)" "unprognostic (7.21e-2)" "unprognostic (2.80e-1)" "unprognostic (3.96e-1)" "unprognostic (5.23e-3)" "unprognostic (7.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-2)" "unprognostic (8.58e-3)" 4.6 3.6 3.2 6.0 3.6 20.2 4.8 4.1 5.1 3.7 1.8 4.4 3.8 3.0 4.5 3.5 2.9 3.7 2.9 4.1 4.7 4.4 7.0 4.1 8.6 4.0 3.6 3.9 4.0 5.6 1.6 4.4 4.4 3.6 4.1 4.5 4.2 3.1 5.3 3.3 3.6 3.3 3.4 8.8 4.5 5.7 5.0 5.3 4.2 5.3 7.7 4.1 2.4 4.3 8.5 7.6 3.8 5.1 11.5 8.1 3.7 6.7 6.7 5.0 5.8 4.5 7.8 11.5 1.9 9.0 6.2 7.4 6.2 5.6 7.2 8.6 4.5 12.8 7.5 5.6 6.9 4.3 13.2 8.7 8.1 5.5 9.9 6.1 5.5 6.1 8.8 10.8 7.5 4.1 9.4 7.4 7.3 7.1 5.2 5.9 6.0 5.8 7.3 6.6 2.2 4.3 5.2 7.8 6.0 4.8 8.0 7.0 11.1 6.6 4.9 5.9 4.5 9.5 5.0 11.9 6.6 6.0 5.1 10.0 2.7 5.9 3.4 4.3 2.8 1.7 2.1 2.5 2.9 2.2 1.7 2.2 9.7 2.4 8.3 1.1 2.8 1.7 3.2 3.6 4.1 5.1 4.1 4.7 4.0 3.6 4.4 3.4 5.0 4.3 18.6 19.2 15.2 9.8 18.5 17.0 9.3 10.3 12.5 11.0 12.6 9.4 20.3 11.5 12.8 7.3 22.9 10.4 38.9 18.4 3.9 10.2 7.5 16.7 17.1 14.2 6.0 23.4 17.6 13.6 5.5 15.0 15.3 16.4 19.0 12.4 17.2 22.9 14.9 11.8 18.1 15.5 8.2 47.3 20.4 5.2 8.1 25.6 10.6 14.0 28.6 11.9 39.1 13.6 21.1 13.0 16.6 15.8 21.8 14.2 14.7 12.8 18.6 12.1 6.6 21.7 20.2 32.9 16.6 16.3 20.6 9.9 28.6 11.8 13.2 16.9 VPS25 "DERP9, EAP20, MGC10540" ENSG00000131475 "Vacuolar protein sorting 25 homolog" Q9BRG1 17 42773449-42779599 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004978, HPA021992, HPA052217, HPA057284" Uncertain Supported Vesicles NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004978: AB_426095, HPA021992: , HPA052217: AB_2681765, HPA057284: AB_2683397" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-4)" "unprognostic (7.37e-2)" "unprognostic (7.57e-2)" "unprognostic (9.83e-3)" "unprognostic (2.76e-3)" "unprognostic (5.84e-2)" "unprognostic (1.25e-1)" "unprognostic (2.90e-1)" "unprognostic (8.10e-3)" "unprognostic (3.88e-1)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.91e-2)" 36.6 40.3 32.8 32.5 33.0 44.3 53.3 34.8 36.8 41.6 36.6 61.9 53.8 35.5 65.3 91.4 58.9 33.4 43.5 32.9 33.2 70.1 68.6 31.8 37.8 32.9 32.8 33.2 49.0 72.3 27.6 46.7 33.5 40.2 68.4 31.2 48.7 36.5 51.3 50.5 45.4 42.8 33.5 37.1 50.0 27.4 33.8 51.3 40.9 41.3 57.2 44.8 44.3 34.0 67.2 136.6 101.8 62.1 126.9 86.5 94.5 83.0 117.1 167.5 116.3 117.9 77.0 66.8 135.8 122.0 88.5 68.7 142.2 181.8 107.9 61.2 178.7 50.6 87.0 177.5 131.0 95.7 64.6 118.2 115.4 148.9 158.0 99.1 106.7 79.0 175.6 65.5 102.1 96.5 138.8 105.2 78.9 152.0 95.3 51.1 123.3 108.7 202.6 75.8 86.3 66.7 46.8 60.1 129.6 155.8 138.4 100.2 58.0 105.7 68.4 60.0 90.3 64.0 39.4 97.9 92.7 64.5 79.6 85.1 76.9 106.7 38.8 89.0 39.9 48.8 42.4 46.4 80.3 46.6 42.3 40.7 44.9 78.9 82.7 54.1 43.1 59.6 32.8 33.0 34.8 36.8 32.9 33.2 32.9 32.8 33.5 33.5 33.8 34.0 26.3 25.6 36.3 4.2 25.3 13.9 41.0 88.3 16.5 24.1 44.4 46.6 26.9 51.5 65.7 62.5 14.6 136.1 22.0 74.3 133.1 135.9 2.6 61.8 48.5 35.4 41.0 47.9 3.5 152.4 186.5 40.8 40.8 55.9 29.2 21.5 29.6 46.4 102.3 23.5 3.5 70.5 85.5 34.5 12.7 5.6 27.7 33.0 42.7 0.0 46.7 56.1 44.3 2.5 4.7 134.4 75.7 30.5 40.9 44.4 83.5 93.6 74.9 29.5 32.9 13.5 69.9 42.8 46.7 61.9 22.9 121.6 22.8 69.9 63.4 53.5 VPS29 "DC15, DC7, PEP11" ENSG00000111237 "VPS29 retromer complex component" Q9UBQ0 12 110491083-110502111 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039748 Uncertain Supported Vesicles,Cytosol NA NA 110000 "Cluster 51: Monocytes - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "HPA039748: AB_10674426" "unprognostic (9.46e-2)" "unprognostic (3.46e-3)" "unprognostic (2.16e-2)" "unprognostic (2.58e-1)" "unprognostic (3.08e-1)" "unprognostic (2.26e-2)" "prognostic unfavorable (2.79e-5)" "unprognostic (1.52e-1)" "unprognostic (3.37e-2)" "prognostic favorable (7.70e-4)" "unprognostic (1.64e-1)" "unprognostic (2.10e-3)" "unprognostic (2.96e-1)" "unprognostic (2.04e-2)" "unprognostic (2.11e-1)" "unprognostic (5.57e-2)" "unprognostic (4.29e-3)" 61.1 62.7 45.6 57.0 47.0 96.2 59.2 46.2 61.8 50.3 47.0 76.4 64.1 52.9 89.5 71.1 50.3 51.1 73.8 48.7 48.3 79.2 77.6 54.9 69.7 47.2 46.3 47.1 56.6 54.8 53.7 47.3 47.4 62.7 79.0 99.6 58.5 71.3 127.3 46.8 65.7 67.1 48.0 76.5 62.8 32.6 46.1 63.2 54.1 100.8 72.0 65.1 50.6 51.1 103.5 98.6 91.9 65.6 100.4 98.7 72.6 94.9 98.1 93.9 84.2 100.0 87.0 94.0 97.1 94.3 87.7 95.5 123.1 88.0 97.0 112.2 98.9 115.4 122.6 83.0 87.4 139.5 97.1 66.0 73.3 79.3 87.4 114.1 166.0 116.6 112.1 85.5 170.0 51.9 110.3 196.4 52.6 90.9 124.8 72.2 93.5 131.8 157.0 149.7 98.1 51.8 107.9 94.0 122.8 78.5 128.6 106.0 94.0 80.6 53.4 112.9 113.0 58.0 87.5 112.1 93.9 130.8 87.8 246.2 262.7 259.4 139.1 356.8 155.3 195.9 175.5 164.9 318.3 158.7 159.8 156.8 178.7 202.9 405.4 214.0 224.8 385.1 45.6 47.0 46.2 61.8 48.7 48.3 47.2 46.3 47.4 48.0 46.1 51.1 138.8 76.9 96.2 21.2 93.7 143.5 172.6 395.9 70.6 39.0 93.4 109.2 282.4 90.1 209.7 101.2 27.1 192.8 116.5 156.3 289.5 231.0 56.8 94.7 79.8 125.0 83.2 147.5 30.2 179.8 187.6 120.2 60.1 104.1 153.9 78.1 94.9 158.7 409.9 42.1 26.7 149.8 248.2 158.0 296.1 82.6 92.2 178.7 177.9 30.9 295.2 107.9 101.0 22.6 30.4 217.9 182.2 105.7 94.8 157.4 142.2 404.7 131.1 111.8 157.8 81.9 212.1 256.4 148.4 108.3 173.0 178.8 111.2 105.8 164.5 187.7 VPS72 "Swc2, TCFL1, YL-1, YL1" ENSG00000163159 "Vacuolar protein sorting 72 homolog" Q15906 1 151176304-151195321 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065709 Approved "Nuclear speckles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA065709: AB_2685540" "unprognostic (2.55e-1)" "unprognostic (3.79e-1)" "unprognostic (3.10e-1)" "unprognostic (4.50e-2)" "unprognostic (2.16e-2)" "unprognostic (7.00e-2)" "prognostic unfavorable (4.41e-6)" "unprognostic (4.10e-2)" "unprognostic (2.25e-1)" "unprognostic (1.10e-2)" "unprognostic (9.58e-2)" "unprognostic (1.50e-1)" "unprognostic (7.92e-2)" "unprognostic (4.52e-2)" "unprognostic (4.92e-2)" "unprognostic (4.49e-2)" "unprognostic (1.30e-1)" 23.8 21.0 33.3 17.0 34.1 12.9 22.7 35.3 39.7 27.5 30.0 26.8 16.8 28.1 19.0 25.0 23.5 15.0 25.4 32.9 35.9 24.9 17.9 18.7 21.2 34.2 33.6 25.8 21.5 21.2 19.1 22.3 34.6 25.8 16.2 18.2 23.5 18.1 56.3 24.3 20.5 24.2 33.6 23.5 23.8 18.7 34.3 27.9 20.0 32.3 26.3 32.2 23.6 36.5 60.7 41.0 92.8 66.9 40.1 35.0 79.5 64.2 33.8 50.4 36.4 43.7 49.4 60.6 77.3 48.7 35.0 56.0 69.1 41.4 38.0 72.2 75.4 52.3 31.0 30.2 55.7 77.8 46.0 28.5 56.8 57.4 47.5 52.8 66.7 74.3 100.2 44.5 40.3 103.3 67.0 54.8 108.5 107.5 69.2 73.2 52.9 95.3 47.1 30.5 65.5 116.8 44.1 67.6 78.9 86.6 76.5 114.4 63.2 26.5 44.9 42.7 82.3 82.5 124.9 96.4 43.4 52.9 49.9 63.3 48.8 82.4 57.2 47.5 55.4 65.8 50.9 49.3 55.3 53.9 50.3 45.6 35.7 75.3 40.6 35.2 67.5 58.3 33.3 34.1 35.3 39.7 32.9 35.9 34.2 33.6 34.6 33.6 34.3 36.5 23.3 6.4 9.1 7.5 21.9 28.4 28.6 40.0 28.5 13.7 24.8 32.1 15.1 24.3 26.8 23.9 4.2 57.6 19.1 24.6 64.6 49.9 12.2 15.2 18.1 25.2 20.3 30.9 6.3 46.4 53.5 24.3 20.9 17.4 31.7 25.4 25.0 18.1 32.0 15.2 6.9 30.6 63.1 22.9 18.8 9.7 25.1 17.7 42.7 2.8 33.8 32.8 29.9 4.5 9.1 59.8 30.5 24.8 13.5 31.4 28.6 35.4 15.7 12.9 52.6 23.3 40.7 39.5 30.4 23.5 31.7 63.1 24.8 16.1 27.1 35.5 WDR12 "FLJ10881, YTM1" ENSG00000138442 "WD repeat domain 12" Q9GZL7 2 202874261-203014798 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036389 Uncertain Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoli "HPA036389: AB_10670716" "unprognostic (1.08e-2)" "unprognostic (3.59e-1)" "unprognostic (8.17e-2)" "unprognostic (3.59e-3)" "unprognostic (1.24e-2)" "unprognostic (9.40e-3)" "prognostic unfavorable (2.57e-6)" "unprognostic (1.52e-1)" "unprognostic (6.14e-2)" "unprognostic (4.78e-2)" "unprognostic (4.58e-2)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "unprognostic (5.21e-2)" "unprognostic (2.66e-1)" "unprognostic (9.69e-3)" "unprognostic (4.48e-2)" 2.6 3.6 2.1 2.7 2.3 3.6 3.6 2.3 3.2 2.5 1.4 3.0 4.1 3.2 3.2 3.2 3.1 2.3 4.0 2.2 2.9 5.2 4.2 1.7 3.3 2.5 2.1 3.2 2.2 3.5 1.9 2.7 2.7 2.2 4.0 2.6 1.9 2.3 4.8 3.6 2.9 3.4 1.5 2.1 2.3 3.5 2.8 3.2 3.2 6.0 3.7 4.1 2.3 2.5 5.3 5.8 6.4 12.5 12.3 10.4 11.4 7.6 6.6 10.1 9.8 14.8 7.5 10.2 7.2 6.6 8.5 6.6 18.2 13.3 16.0 4.6 11.1 17.0 9.0 17.7 8.0 22.1 9.9 9.5 9.4 12.0 23.6 6.4 10.8 10.2 26.7 5.9 11.3 6.5 14.8 13.3 14.9 7.3 14.3 11.1 9.7 16.1 11.2 6.5 11.4 9.8 6.5 8.2 9.8 11.0 4.7 14.1 8.3 8.3 6.9 7.4 8.4 8.0 12.8 16.3 8.7 15.3 8.8 1.3 1.6 0.6 1.4 1.7 2.0 1.9 1.3 1.4 2.1 1.9 1.7 1.7 0.6 1.3 1.7 2.4 1.6 1.1 2.1 2.3 2.3 3.2 2.2 2.9 2.5 2.1 2.7 1.5 2.8 2.5 10.1 9.6 16.9 12.1 13.6 20.5 21.4 24.4 13.1 10.2 8.4 9.1 27.9 7.2 19.1 5.5 2.1 25.3 7.9 7.8 15.6 18.0 14.3 14.7 25.3 12.6 5.4 22.1 19.2 10.6 34.9 16.5 9.7 13.3 15.2 15.8 8.2 15.0 18.0 15.2 20.3 10.6 24.4 7.2 6.0 8.9 17.1 9.2 1.8 12.2 13.7 6.4 5.2 10.6 9.9 14.2 6.6 15.4 9.3 17.3 13.9 38.1 15.7 8.3 13.1 20.1 41.9 43.0 32.3 18.2 17.3 21.5 10.7 21.0 19.2 17.0 WDR61 REC14 ENSG00000140395 "WD repeat domain 61" Q9GZS3 15 78277835-78299703 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039932, HPA040065" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 28000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA039932: AB_10796336, HPA040065: AB_10793926" "unprognostic (1.08e-1)" "unprognostic (1.85e-2)" "unprognostic (8.91e-2)" "unprognostic (1.07e-1)" "unprognostic (2.09e-1)" "unprognostic (3.36e-1)" "unprognostic (2.44e-1)" "unprognostic (1.60e-1)" "unprognostic (3.05e-1)" "unprognostic (2.74e-3)" "unprognostic (4.21e-1)" "unprognostic (5.72e-2)" "prognostic favorable (2.03e-10)" "unprognostic (1.04e-1)" "unprognostic (3.13e-1)" "unprognostic (3.18e-1)" "unprognostic (1.09e-2)" 38.8 52.7 34.5 29.6 36.5 61.5 59.9 50.4 63.0 40.8 31.1 39.5 36.2 34.9 115.7 40.1 46.6 28.6 41.0 40.8 40.4 60.8 50.9 34.6 37.4 41.5 41.2 34.6 41.3 55.6 49.9 35.5 40.0 46.0 43.5 49.4 39.5 37.4 45.4 52.1 30.4 41.4 38.2 29.9 33.5 49.0 37.0 48.5 56.8 38.2 46.0 41.4 32.4 61.5 39.3 92.4 74.3 77.4 74.1 61.6 56.1 60.9 68.6 76.6 73.6 87.9 67.9 80.7 72.6 69.8 119.2 78.2 165.8 71.5 58.3 53.9 123.8 66.2 79.9 84.6 62.6 99.2 63.3 52.8 50.5 30.8 24.0 52.7 82.7 80.0 113.1 78.8 92.5 116.6 82.3 81.6 54.3 98.5 76.2 74.7 59.7 89.1 81.3 112.3 103.7 56.2 88.0 90.9 323.7 76.9 56.0 124.2 58.2 53.7 66.0 38.2 103.6 69.3 113.7 113.0 80.5 153.3 112.6 39.0 91.2 33.6 59.6 100.0 65.0 66.4 59.7 62.1 134.2 53.5 62.2 68.6 7.7 72.4 86.0 71.6 72.7 89.1 34.5 36.5 50.4 63.0 40.8 40.4 41.5 41.2 40.0 38.2 37.0 61.5 38.7 35.3 44.7 20.5 26.7 49.1 61.5 105.0 31.9 57.2 44.8 47.2 25.8 28.6 57.5 38.6 47.9 106.1 29.2 23.2 125.2 62.5 32.2 41.5 38.6 42.2 23.4 37.6 34.6 55.6 78.1 51.0 20.4 29.1 47.5 49.1 40.0 47.0 66.1 43.7 36.8 38.0 93.6 37.0 47.2 12.4 50.1 37.0 58.7 12.2 61.1 81.9 42.2 17.1 33.1 41.0 28.5 50.8 36.4 51.6 35.4 132.7 70.1 50.7 6.6 37.8 90.2 122.4 60.2 38.3 58.7 92.4 31.7 59.4 52.4 57.7 WNK1 "HSAN2, HSN2, PPP1R167, PRKWNK1" ENSG00000060237 "WNK lysine deficient protein kinase 1" Q9H4A3 12 752579-911452 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein kinase inhibitor, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 293.0" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046541, HPA059157" Enhanced Supported Cytosol NA NA 92000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA046541: AB_2679690, HPA059157: AB_2683935" "unprognostic (1.40e-1)" "unprognostic (1.54e-2)" "unprognostic (4.82e-2)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (7.68e-2)" "unprognostic (1.05e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.67e-4)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (4.38e-1)" "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (5.17e-2)" "unprognostic (1.30e-2)" 56.7 20.6 190.8 36.4 236.8 54.2 33.5 179.4 166.1 32.8 110.8 22.8 14.4 26.7 30.4 72.1 29.4 27.1 63.8 132.3 161.1 84.0 31.6 44.6 39.2 232.3 238.4 30.1 22.5 51.1 17.0 36.0 217.0 29.7 24.2 87.4 24.0 33.4 79.7 52.0 17.4 36.1 225.4 30.2 27.6 48.3 238.0 61.3 27.7 79.8 46.9 35.8 43.8 293.0 53.9 97.5 131.8 11.3 88.1 80.0 52.2 48.3 61.6 58.2 51.3 59.4 55.7 71.0 16.8 107.8 73.5 39.8 93.8 56.7 84.3 124.7 51.4 169.4 122.2 46.1 66.7 86.9 68.2 64.0 82.1 97.6 164.4 61.6 73.4 68.0 76.4 158.2 77.8 54.1 154.6 15.6 105.8 47.8 24.3 78.0 138.8 20.8 80.6 96.8 35.1 40.7 121.8 82.9 33.6 183.3 86.8 97.2 78.3 67.1 77.3 86.2 70.8 23.8 43.1 103.8 59.4 44.6 53.2 0.7 1.8 1.6 1.9 2.1 1.9 1.7 1.9 2.1 1.4 1.2 1.2 1.9 5.6 1.4 4.7 1.2 3.4 1.6 190.8 236.8 179.4 166.1 132.3 161.1 232.3 238.4 217.0 225.4 238.0 293.0 261.1 102.5 141.6 77.1 65.3 112.8 42.3 38.3 85.4 87.9 50.6 39.5 241.6 50.1 47.1 90.1 150.1 32.5 83.0 27.8 86.1 28.0 29.7 63.0 68.6 106.7 58.7 304.2 182.3 24.4 32.9 58.3 37.2 70.2 52.6 46.2 52.5 71.7 57.3 84.1 165.0 26.3 16.2 121.4 80.8 21.2 61.8 96.7 37.4 114.3 95.7 64.0 61.8 126.7 336.4 41.7 34.8 55.7 76.5 59.0 24.2 21.8 64.6 96.1 13.1 69.6 63.8 186.5 74.6 147.2 136.0 28.5 112.9 33.2 25.8 55.2 XRCC5 "KARP-1, KU80, Ku86, KUB2" ENSG00000079246 "X-ray repair cross complementing 5" P13010 2 216107464-216206303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004468, HPA025813, HPA064685" Supported Enhanced Nucleoplasm NA NA 940000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004468: AB_672929, HPA025813: AB_1858901, HPA064685: AB_2685322" "unprognostic (4.23e-2)" "unprognostic (1.75e-1)" "unprognostic (9.07e-3)" "unprognostic (3.44e-3)" "unprognostic (2.44e-2)" "unprognostic (7.00e-2)" "prognostic unfavorable (2.10e-7)" "unprognostic (4.42e-3)" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (3.38e-3)" "unprognostic (1.96e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-1)" "unprognostic (2.88e-2)" "unprognostic (3.58e-2)" "unprognostic (6.01e-2)" 79.6 74.0 52.8 102.4 58.4 112.0 114.6 56.0 69.9 96.4 38.1 91.0 82.2 103.3 85.3 96.8 95.8 83.2 77.1 58.1 56.4 100.2 140.6 76.6 127.8 52.4 50.7 104.0 71.7 118.4 61.4 87.1 54.4 84.7 106.6 102.0 71.6 91.3 103.1 91.6 82.3 100.1 59.1 83.9 77.0 69.5 51.0 176.8 129.2 92.7 140.9 131.7 72.7 65.6 234.4 194.9 427.0 230.5 185.5 210.9 256.6 269.9 279.2 307.1 328.5 421.0 225.7 225.6 214.8 239.1 269.2 203.5 425.2 329.5 469.7 215.0 291.0 488.5 282.9 398.0 229.2 437.1 230.0 193.5 172.1 361.2 156.6 218.4 368.0 272.1 314.4 199.7 405.9 225.9 496.7 221.7 498.0 236.0 170.6 429.8 376.7 186.5 331.9 262.6 372.6 314.6 217.8 159.9 201.1 428.5 196.7 325.8 264.2 287.3 241.5 190.6 312.3 240.0 311.4 493.6 223.4 339.5 290.0 253.2 172.7 175.0 153.6 177.1 165.3 121.2 148.1 157.0 168.0 121.6 147.6 149.1 192.7 172.9 217.4 102.1 167.5 330.4 52.8 58.4 56.0 69.9 58.1 56.4 52.4 50.7 54.4 59.1 51.0 65.6 129.0 105.8 126.3 65.6 131.0 113.7 174.0 242.4 90.5 136.7 93.6 87.1 163.0 105.8 190.0 101.2 45.9 210.5 141.6 79.8 97.8 304.3 103.0 147.4 175.4 142.4 133.3 159.4 73.9 235.8 238.8 134.1 74.5 159.1 146.7 140.2 82.8 222.5 157.3 89.2 82.4 90.7 173.0 100.5 85.3 30.0 101.5 130.7 69.4 108.7 310.9 142.0 138.0 93.0 111.4 247.9 70.3 129.4 132.5 137.4 82.8 139.9 160.1 114.0 111.7 142.9 161.3 252.2 179.2 114.7 120.3 165.5 149.7 165.3 112.0 161.2 XRN2 ENSG00000088930 "5'-3' exoribonuclease 2" Q9H0D6 20 21303331-21389825 "Predicted intracellular proteins" "mRNA processing, Transcription, Transcription regulation, Transcription termination" "DNA-binding, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047118, HPA050485" Supported Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" Nucleoli Nucleoplasm "HPA047118: AB_2679941, HPA050485: AB_2681141" "unprognostic (9.38e-2)" "unprognostic (4.70e-2)" "unprognostic (2.07e-2)" "unprognostic (3.09e-2)" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.54e-5)" "unprognostic (7.26e-2)" "unprognostic (1.05e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-2)" "unprognostic (1.40e-1)" "unprognostic (1.99e-3)" "unprognostic (1.22e-1)" "unprognostic (1.97e-1)" "unprognostic (1.63e-2)" "unprognostic (1.31e-1)" 36.1 36.1 14.7 42.6 17.2 73.3 42.9 18.5 15.8 33.4 21.1 29.9 24.3 37.0 31.3 25.9 33.2 35.8 24.8 13.6 16.5 34.8 42.7 34.4 43.2 16.5 15.5 36.7 32.8 45.2 18.7 37.4 17.0 28.4 32.4 24.8 27.0 33.6 38.2 24.3 24.8 39.4 16.1 36.1 24.9 29.9 16.1 46.8 41.2 26.5 45.8 46.5 23.1 18.3 91.9 106.7 115.1 88.7 84.1 102.7 113.7 82.3 107.1 107.2 124.1 71.8 102.2 89.7 47.8 86.8 146.1 106.0 131.0 138.7 136.6 40.8 66.0 116.0 37.7 136.5 73.9 105.7 96.8 98.0 68.7 118.5 103.1 95.3 93.6 84.5 94.9 74.7 101.0 71.7 156.5 69.6 89.8 88.8 71.1 113.1 195.4 76.9 91.0 95.6 88.9 115.2 96.0 116.6 89.9 88.6 65.5 123.9 87.0 107.0 79.8 24.8 105.4 65.3 90.0 95.0 41.5 48.5 82.5 36.0 68.6 49.2 34.6 54.8 46.4 30.5 37.7 38.1 61.1 30.9 39.8 38.7 69.2 43.9 71.8 26.2 49.2 54.3 14.7 17.2 18.5 15.8 13.6 16.5 16.5 15.5 17.0 16.1 16.1 18.3 118.6 60.9 112.2 29.7 72.4 63.6 90.8 81.2 64.9 44.9 85.0 75.2 58.7 52.9 94.4 40.5 41.7 106.2 99.1 36.6 27.4 123.8 157.6 119.5 128.5 99.9 59.5 62.6 45.7 120.9 96.8 80.1 39.8 113.7 83.5 92.0 41.0 70.4 105.4 50.5 48.9 52.6 67.1 129.6 57.9 26.8 57.8 111.2 60.5 49.6 165.9 55.1 85.5 46.8 67.6 96.1 53.7 55.7 77.1 91.6 45.1 80.6 102.7 49.7 59.2 120.1 108.1 104.1 116.6 65.6 67.2 105.2 83.5 99.4 68.1 89.7 YIF1A "54TM, FinGER7, YIF1, YIF1P" ENSG00000174851 "Yip1 interacting factor homolog A, membrane trafficking protein" O95070 11 66284580-66289145 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014840, HPA076194" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "HPA014840: AB_2217189, HPA076194: " "unprognostic (9.35e-2)" "unprognostic (7.86e-2)" "unprognostic (1.37e-1)" "unprognostic (1.94e-1)" "unprognostic (3.23e-1)" "unprognostic (4.38e-3)" "unprognostic (2.25e-3)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (2.13e-1)" "unprognostic (6.39e-3)" "unprognostic (1.35e-1)" "unprognostic (2.60e-2)" "unprognostic (2.03e-1)" "unprognostic (2.64e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (8.70e-4)" 49.2 54.7 33.4 28.4 36.0 16.7 47.5 38.5 41.4 42.7 42.4 50.8 56.5 53.5 34.5 50.9 45.7 25.5 57.8 33.5 35.6 50.9 149.5 44.9 22.9 38.9 36.1 42.1 86.0 40.6 74.1 34.5 38.2 47.3 37.7 12.3 51.1 29.6 96.2 43.0 47.4 41.1 38.5 35.9 56.1 36.4 35.6 21.6 49.9 59.3 24.7 45.4 40.6 41.9 80.7 131.3 39.4 72.6 130.0 138.7 73.8 114.4 122.3 95.5 94.3 126.0 95.5 67.9 111.5 161.4 107.8 119.9 60.7 107.9 75.6 77.7 72.0 42.5 93.3 158.7 147.4 59.3 61.5 97.4 144.4 98.6 158.9 76.6 91.3 67.0 80.7 114.8 84.3 199.3 71.3 64.4 40.3 147.4 136.6 54.9 61.2 203.9 81.9 70.9 58.5 57.9 62.5 106.7 103.4 49.6 155.5 43.5 81.0 80.8 69.0 165.3 54.1 78.1 86.0 63.0 125.4 56.2 90.2 19.4 95.6 20.6 71.3 141.4 78.4 95.9 60.6 67.2 116.4 82.4 48.0 55.3 9.4 51.2 140.0 141.6 54.9 99.8 33.4 36.0 38.5 41.4 33.5 35.6 38.9 36.1 38.2 38.5 35.6 41.9 63.4 38.5 48.0 6.2 52.2 36.1 88.1 170.4 38.1 27.1 84.4 92.7 34.5 82.9 115.5 46.0 22.9 114.3 42.6 66.8 64.6 137.9 28.1 42.1 84.8 53.6 87.4 21.0 1.9 149.4 248.5 90.4 55.0 42.8 29.9 38.8 49.2 172.0 105.4 26.9 3.9 140.9 116.0 38.4 44.9 48.6 75.5 45.0 72.9 8.4 40.8 73.7 28.8 10.1 10.4 132.1 93.3 82.4 92.4 195.2 202.2 135.2 101.4 34.0 39.5 60.8 150.0 61.0 56.8 63.3 46.3 154.3 36.5 88.1 107.2 112.1 YIF1B FinGER8 ENSG00000167645 "Yip1 interacting factor homolog B, membrane trafficking protein" Q5BJH7 19 38303558-38317273 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039328, HPA055257, HPA062675" Approved Approved "Golgi apparatus,Vesicles" NA NA 37000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Vesicles "Golgi apparatus" "HPA039328: AB_2676445, HPA055257: AB_2682762, HPA062675: AB_2684830" "unprognostic (2.51e-1)" "unprognostic (3.34e-1)" "unprognostic (1.38e-1)" "unprognostic (6.81e-2)" "unprognostic (1.45e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.53e-5)" "unprognostic (1.37e-1)" "unprognostic (1.45e-2)" "unprognostic (5.53e-2)" "prognostic favorable (1.88e-4)" "unprognostic (4.57e-2)" "unprognostic (2.40e-2)" "unprognostic (3.69e-1)" "unprognostic (1.26e-1)" "unprognostic (2.64e-1)" "unprognostic (3.94e-3)" 30.1 30.7 29.3 33.0 32.4 69.1 26.7 37.0 38.3 33.5 29.0 26.6 20.4 24.1 10.9 33.2 25.6 16.5 40.6 30.2 32.6 27.2 58.3 35.7 32.1 36.3 30.9 26.7 27.1 16.9 29.1 23.5 38.6 23.7 16.1 13.6 30.2 12.5 35.0 26.0 24.0 18.1 33.4 47.7 22.0 23.1 34.0 20.9 19.8 26.7 20.9 26.8 25.6 38.5 43.7 108.9 48.3 57.5 68.4 63.5 37.8 103.2 79.0 75.7 110.7 53.5 32.6 75.7 44.4 121.1 81.5 27.4 85.9 54.6 28.7 81.1 43.3 117.0 48.2 56.5 94.8 82.4 132.9 52.3 47.9 78.0 33.8 76.1 71.3 99.4 152.9 205.3 68.5 46.0 87.6 98.9 37.0 74.9 33.7 89.0 58.6 117.9 48.9 40.6 34.8 58.1 34.5 76.7 55.4 37.2 29.9 163.2 68.8 74.6 73.2 108.4 83.9 76.4 122.1 51.8 96.1 150.5 54.6 81.9 155.7 179.0 60.8 119.4 54.4 49.3 57.3 54.8 300.3 42.7 46.7 47.5 42.8 44.0 70.8 127.0 59.0 120.2 29.3 32.4 37.0 38.3 30.2 32.6 36.3 30.9 38.6 33.4 34.0 38.5 27.4 0.0 5.5 5.5 22.8 17.7 19.4 25.8 18.2 12.2 22.6 18.7 4.7 18.6 14.2 22.0 12.5 44.7 17.0 16.0 0.0 39.4 6.3 17.5 18.2 23.9 14.4 33.2 7.3 27.7 52.9 23.8 16.3 18.6 22.9 43.4 37.1 30.5 94.4 11.8 7.4 24.7 32.6 42.3 37.4 8.5 9.0 53.3 35.6 3.7 34.4 20.8 16.5 4.0 12.7 15.5 13.5 9.1 69.4 14.8 8.1 16.1 20.7 15.5 6.6 11.1 40.3 20.6 31.9 30.7 20.0 27.6 18.8 26.2 25.9 19.5 YTHDF2 "CAHL, HGRG8, NY-REN-2" ENSG00000198492 "YTH N6-methyladenosine RNA binding protein 2" Q9Y5A9 1 28736621-28769775 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Host-virus interaction, Immunity, Innate immunity, Mitosis, Oogenesis, Spermatogenesis" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030063, HPA054080, HPA059621" Approved Enhanced "Cytosol,Cytoplasmic bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Cytoplasmic bodies" "HPA030063: AB_2732453, HPA054080: AB_2682371, HPA059621: AB_2684084" "unprognostic (8.75e-2)" "unprognostic (1.90e-2)" "unprognostic (4.66e-3)" "unprognostic (1.63e-1)" "unprognostic (3.03e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (6.14e-9)" "unprognostic (1.75e-2)" "unprognostic (4.82e-2)" "unprognostic (4.18e-2)" "unprognostic (1.69e-1)" "unprognostic (4.11e-2)" "unprognostic (2.07e-1)" "unprognostic (1.21e-1)" "unprognostic (6.38e-2)" "unprognostic (9.29e-2)" "unprognostic (6.97e-3)" 33.5 33.0 20.0 26.7 21.0 63.9 38.3 22.1 24.8 27.5 29.5 32.0 29.4 27.8 43.6 37.5 27.7 27.0 27.0 21.3 22.5 31.8 42.2 35.6 35.6 20.2 19.6 29.3 27.4 37.1 18.0 34.4 20.6 22.9 33.8 20.2 39.8 23.9 43.9 41.9 26.2 32.9 21.4 32.1 27.6 29.3 21.2 44.1 28.0 33.7 43.8 32.8 26.1 23.1 68.8 46.3 99.6 96.8 75.5 58.1 117.8 66.1 80.7 80.0 80.4 42.8 78.1 117.8 64.4 84.4 47.8 62.2 117.3 105.7 94.0 76.0 91.9 98.7 60.7 78.4 90.0 105.1 74.4 78.5 106.4 86.1 121.1 70.0 99.0 70.0 101.9 55.6 89.7 53.3 112.1 80.8 161.8 61.1 61.1 95.4 74.2 96.8 111.3 95.8 85.7 91.2 68.6 102.1 181.7 82.6 67.8 95.8 69.4 55.4 57.8 52.5 93.5 68.2 47.7 133.3 63.3 81.2 89.9 108.3 78.4 78.7 66.1 91.1 88.3 80.3 72.7 80.3 96.7 59.0 77.9 73.2 26.5 92.4 94.4 62.6 92.3 109.5 20.0 21.0 22.1 24.8 21.3 22.5 20.2 19.6 20.6 21.4 21.2 23.1 70.8 51.3 61.2 13.7 70.8 152.7 104.9 111.0 109.8 45.4 110.2 101.3 52.8 77.2 85.3 44.1 31.3 149.6 79.5 46.4 66.5 102.0 16.3 65.8 78.2 78.5 75.7 52.8 22.5 69.6 108.3 64.5 49.5 76.6 72.3 63.6 77.4 102.3 77.3 58.9 20.4 76.0 105.8 65.4 75.4 19.3 71.1 56.7 37.4 21.5 74.1 66.4 73.2 14.1 23.5 80.7 43.8 75.2 71.0 78.6 42.4 96.0 53.8 45.9 92.1 61.5 83.0 142.2 115.5 95.3 161.7 260.2 69.2 69.5 65.9 118.7 YWHAE FLJ45465 ENSG00000108953 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon" P62258 17 1344275-1400222 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008445, CAB016200, CAB021109, CAB047350" Approved Supported Cytosol NA NA 83000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016200: AB_626619, CAB021109: AB_10060396, CAB047350: , HPA008445: AB_1844336" "unprognostic (1.29e-1)" "unprognostic (1.50e-1)" "unprognostic (3.99e-2)" "prognostic favorable (6.48e-6)" "unprognostic (1.59e-1)" "unprognostic (2.91e-2)" "unprognostic (2.73e-2)" "unprognostic (4.77e-3)" "unprognostic (4.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.59e-1)" "unprognostic (2.73e-1)" "unprognostic (1.92e-3)" "unprognostic (8.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.24e-2)" "unprognostic (8.94e-2)" 221.9 198.9 251.8 122.8 264.2 121.3 198.7 266.3 272.8 168.8 195.7 161.1 136.8 155.6 192.7 239.1 188.1 103.7 242.3 260.7 275.4 229.3 211.7 176.9 113.7 271.1 246.8 170.8 154.9 236.9 178.8 198.2 267.1 150.0 168.1 220.8 184.8 121.6 656.7 193.3 129.3 137.3 279.2 101.5 136.9 165.4 262.2 211.0 208.5 441.8 164.5 186.9 179.7 302.7 615.3 565.8 700.2 563.4 376.9 454.7 589.8 382.1 481.5 724.5 571.3 907.5 305.5 524.7 411.9 621.9 439.7 463.1 859.2 745.6 798.7 294.2 930.9 334.1 366.2 409.4 483.4 277.1 311.1 421.6 458.6 619.3 897.0 520.6 729.2 458.5 402.8 337.9 719.7 368.5 445.8 264.1 566.6 596.9 332.7 477.3 255.9 380.4 547.7 365.7 354.2 497.2 531.1 240.3 364.3 439.9 442.3 290.9 467.4 411.9 293.8 453.7 731.4 190.5 329.9 346.6 478.4 387.5 585.4 78.6 137.2 41.2 47.3 153.6 57.8 78.1 67.3 55.1 180.3 59.1 55.7 51.2 49.9 64.1 144.8 133.8 99.7 151.0 251.8 264.2 266.3 272.8 260.7 275.4 271.1 246.8 267.1 279.2 262.2 302.7 363.6 298.1 194.4 83.2 161.1 573.9 457.5 468.4 281.7 153.6 313.6 219.1 473.4 265.9 310.9 371.5 50.1 463.2 128.7 300.7 745.4 460.8 258.0 573.6 414.3 352.6 352.6 244.7 73.4 421.4 709.5 319.4 194.7 502.7 211.5 328.1 262.3 309.0 384.9 111.0 72.4 346.3 376.4 260.9 434.9 434.3 280.8 227.5 425.2 60.0 320.5 357.8 55.6 56.8 112.1 464.8 289.8 294.9 279.5 487.9 272.1 707.8 504.6 173.3 243.3 361.2 524.6 508.7 573.3 333.8 586.6 519.5 130.7 287.2 361.1 474.4 YWHAQ "14-3-3, HS1" ENSG00000134308 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta" P27348 2 9583967-9630997 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007925, CAB010286" Approved Supported Nucleoplasm,Cytosol NA NA 49000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB010286: AB_2218221, HPA007925: AB_1844340" "unprognostic (2.65e-2)" "unprognostic (3.99e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (1.53e-1)" "unprognostic (5.78e-3)" "prognostic unfavorable (9.83e-6)" "unprognostic (4.90e-3)" "unprognostic (2.98e-2)" "unprognostic (5.51e-2)" "unprognostic (6.18e-2)" "unprognostic (1.45e-1)" "unprognostic (2.95e-2)" "unprognostic (6.74e-2)" "unprognostic (9.75e-2)" "unprognostic (1.63e-1)" "unprognostic (4.39e-3)" 144.6 141.0 190.8 106.1 223.2 178.4 153.6 216.5 239.1 177.0 149.4 161.2 119.4 184.3 141.6 187.3 136.5 122.6 218.7 205.1 229.7 140.0 116.3 119.3 132.0 218.6 203.8 163.2 201.5 131.9 112.9 123.2 212.4 161.1 133.0 143.6 120.2 140.2 53.5 121.5 116.2 177.4 203.9 89.8 127.5 144.6 205.7 148.2 137.6 62.1 141.1 144.4 161.8 280.5 316.1 465.2 412.0 400.3 316.6 434.5 385.7 421.6 412.3 432.5 360.2 352.9 269.3 404.4 214.0 608.5 451.3 288.5 462.8 459.7 553.6 1003.0 374.8 378.8 268.9 379.9 241.1 369.1 219.7 295.8 264.5 473.6 305.9 394.9 493.5 285.6 378.5 236.8 539.3 219.3 658.2 374.4 700.7 351.9 527.5 473.0 533.3 497.4 478.8 276.9 390.1 659.9 384.1 392.2 317.3 343.8 244.4 187.0 453.9 539.6 380.7 473.4 654.4 239.3 351.4 526.6 461.8 378.9 458.8 99.5 102.7 120.5 207.8 137.8 255.6 151.9 192.8 223.5 144.2 147.8 103.6 170.1 31.1 252.0 137.0 73.1 208.4 344.1 190.8 223.2 216.5 239.1 205.1 229.7 218.6 203.8 212.4 203.9 205.7 280.5 186.6 51.3 67.3 26.1 144.0 316.7 366.5 339.0 143.4 201.4 198.4 153.7 82.6 90.1 143.4 136.1 27.1 261.6 189.9 209.9 416.7 371.5 281.9 132.9 175.8 191.0 187.1 179.2 57.3 283.7 615.3 242.0 115.2 131.6 125.0 152.5 84.9 97.9 215.3 572.0 45.1 129.2 270.6 111.9 228.3 360.5 174.0 132.3 295.3 30.0 195.0 229.2 155.5 39.7 186.6 261.2 150.9 250.5 187.9 323.7 135.9 278.8 111.7 105.8 197.2 191.5 312.7 432.2 205.8 252.1 355.3 238.6 217.7 252.9 186.5 457.3 YY1 "DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1" ENSG00000100811 "YY1 transcription factor" P25490 14 100238298-100282788 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, DNA damage, DNA recombination, DNA repair, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001119, CAB009392" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Vesicles" "CAB009392: AB_2218501, HPA001119: AB_1858930" "unprognostic (7.67e-2)" "unprognostic (8.08e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (6.75e-3)" "unprognostic (8.31e-3)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.09e-1)" "unprognostic (4.26e-2)" "unprognostic (7.68e-3)" "unprognostic (1.40e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-2)" "unprognostic (4.36e-2)" "unprognostic (1.66e-1)" "unprognostic (2.30e-1)" "unprognostic (4.30e-1)" 27.2 26.2 20.9 28.9 22.1 56.4 27.0 27.0 24.2 24.6 18.5 30.7 27.9 24.8 34.0 28.9 21.7 22.7 22.8 22.7 20.2 32.9 46.8 24.0 36.0 20.4 20.4 21.6 24.4 32.5 17.4 34.2 20.3 25.2 28.7 20.1 25.1 23.6 36.8 29.0 29.7 24.8 20.1 31.9 26.2 23.8 21.5 52.3 37.2 27.2 38.2 31.9 21.0 26.2 62.0 30.7 64.2 51.5 51.8 65.9 68.1 60.0 55.1 64.7 66.0 38.6 97.7 94.0 82.3 54.5 37.1 64.0 72.6 64.1 88.3 70.8 60.9 86.8 34.6 50.0 48.4 103.8 73.2 38.7 76.4 45.4 61.4 58.6 63.9 67.3 69.9 61.8 63.7 74.5 113.5 61.8 68.7 98.0 56.0 93.9 88.9 50.7 75.8 58.3 68.2 53.3 79.2 57.8 85.1 54.0 86.6 100.1 57.4 39.4 48.3 97.6 53.8 68.3 72.0 126.6 56.4 68.6 52.5 4.8 5.7 11.9 4.3 4.8 5.6 5.3 5.7 5.9 4.9 8.3 5.4 5.4 9.8 9.5 3.8 5.3 7.7 2.7 20.9 22.1 27.0 24.2 22.7 20.2 20.4 20.4 20.3 20.1 21.5 26.2 116.0 54.5 66.8 23.8 102.4 238.0 101.1 49.9 211.7 80.5 129.8 98.2 91.5 92.9 50.0 68.0 81.3 118.6 147.4 122.8 72.4 68.7 10.3 118.7 133.8 115.7 110.1 125.4 28.2 82.0 123.6 106.7 58.1 153.6 71.7 99.4 103.5 119.4 81.3 127.9 26.5 108.8 48.8 111.8 225.8 15.7 94.8 121.6 76.5 30.0 117.8 82.0 114.4 20.6 40.7 80.0 95.5 100.8 125.0 168.9 90.0 104.6 47.6 74.9 92.1 106.5 124.3 86.0 67.0 192.1 243.1 175.5 124.8 124.1 118.7 153.5 ZBTB12 "C6orf46, D6S59E, G10, NG35" ENSG00000204366 "Zinc finger and BTB domain containing 12" Q9Y330 6 31899613-31902086 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.6;Erythroid cells: 2.5;Horizontal cells: 3.3;Oligodendrocytes: 2.2;Rod photoreceptor cells: 1.7;Squamous epithelial cells: 1.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.5;HEK 293: 3.1;NTERA-2: 2.5;REH: 4.6;U-266/84: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047161, HPA070639" Approved Enhanced Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA047161: AB_2679962, HPA070639: " "unprognostic (2.05e-1)" "unprognostic (3.15e-2)" "unprognostic (3.77e-1)" "unprognostic (2.93e-1)" "unprognostic (1.24e-1)" "unprognostic (8.92e-2)" "unprognostic (1.26e-3)" "unprognostic (1.55e-1)" "unprognostic (5.22e-2)" "unprognostic (8.16e-2)" "unprognostic (2.58e-1)" "unprognostic (5.41e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (1.87e-1)" "unprognostic (2.11e-1)" "unprognostic (6.39e-2)" "unprognostic (8.98e-3)" 1.8 2.8 0.6 0.0 0.6 0.0 1.9 0.5 0.7 5.7 0.0 2.7 0.0 5.0 0.0 2.7 4.1 0.1 1.7 0.5 0.3 1.9 1.3 1.5 0.0 0.7 0.7 6.4 2.1 0.0 2.2 0.0 0.6 3.2 0.0 0.0 2.4 0.0 2.0 1.5 2.4 0.0 0.6 2.4 2.1 2.3 0.7 0.0 2.5 0.0 0.0 4.2 3.1 1.1 1.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.1 1.1 0.0 0.0 0.0 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.2 0.0 0.1 0.0 0.5 0.2 2.5 0.0 1.2 4.6 0.3 0.2 0.0 0.0 1.1 1.2 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.1 1.4 0.0 0.1 1.4 3.1 0.6 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.5 0.7 0.5 0.3 0.7 0.7 0.6 0.6 0.7 1.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.8 0.3 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.6 0.4 0.0 2.5 0.4 0.0 0.0 0.2 0.5 0.2 0.0 1.0 0.0 0.0 0.0 3.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.8 0.1 0.0 0.2 0.0 1.7 0.0 0.3 1.1 0.0 0.0 1.5 0.0 0.0 0.2 0.5 0.1 0.1 ZC3H13 "DKFZp434D1812, KIAA0853, Xio" ENSG00000123200 "Zinc finger CCCH-type containing 13" Q5T200 13 45954465-46052759 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 166.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039340, HPA040140, HPA047806" Uncertain Approved "Nuclear membrane,Actin filaments" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear membrane, Actin filaments" "HPA039340: AB_2676454, HPA040140: AB_2676858, HPA047806: AB_2680161" "unprognostic (1.50e-1)" "unprognostic (6.28e-3)" "unprognostic (1.25e-1)" "unprognostic (2.22e-2)" "unprognostic (7.53e-2)" "unprognostic (1.24e-1)" "unprognostic (2.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.77e-1)" "unprognostic (1.71e-1)" "unprognostic (2.01e-1)" "unprognostic (1.38e-1)" "prognostic favorable (2.69e-4)" "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (3.45e-1)" "unprognostic (9.21e-3)" 15.4 10.1 21.9 13.4 26.9 15.0 15.9 16.9 22.0 14.8 6.7 15.0 9.3 18.5 15.3 10.7 12.0 11.4 11.7 17.4 24.9 12.7 58.6 12.6 15.9 18.4 24.2 17.7 9.4 17.7 9.1 15.5 20.4 15.6 12.3 15.7 12.5 14.3 16.0 13.8 11.7 14.6 17.9 16.4 12.0 11.4 25.2 22.5 17.5 15.8 13.1 12.9 11.0 27.3 16.6 20.9 51.1 19.9 36.0 36.6 21.4 29.9 24.5 24.1 15.9 32.3 28.9 46.4 18.8 31.9 16.6 29.0 32.1 25.0 38.4 41.4 32.5 53.3 21.0 28.2 21.2 68.5 28.3 28.2 20.4 25.5 30.0 22.9 26.6 26.5 29.1 13.8 25.6 21.6 34.8 34.7 46.2 31.7 13.4 34.9 33.1 14.2 19.9 25.4 13.4 30.4 29.6 19.0 166.2 33.6 14.7 32.0 44.7 21.5 19.3 19.6 26.3 13.8 17.2 45.5 24.5 35.9 27.8 15.3 4.6 10.5 7.4 5.7 7.4 5.4 5.2 5.8 4.6 5.1 5.1 4.6 7.7 8.8 6.9 7.9 6.3 3.9 21.9 26.9 16.9 22.0 17.4 24.9 18.4 24.2 20.4 17.9 25.2 27.3 79.1 214.7 186.1 37.5 70.9 40.7 65.6 44.2 34.7 84.6 47.3 63.5 164.0 90.1 89.0 55.2 43.8 88.3 75.8 43.6 27.4 64.5 4.2 67.0 114.7 82.7 55.6 117.6 69.4 48.6 78.6 76.2 29.6 79.8 129.3 64.1 75.7 269.2 63.5 85.8 71.2 42.4 40.7 82.5 31.4 11.8 76.7 66.0 28.4 48.7 90.2 87.1 112.3 55.3 149.5 54.7 38.7 81.6 44.0 60.9 34.4 19.5 83.9 69.2 52.6 120.2 99.4 183.6 106.0 37.7 50.6 80.3 80.8 66.9 49.7 54.5 ZCRB1 "MADP-1, MADP1, RBM36, SNRNP31, ZCCHC19" ENSG00000139168 "Zinc finger CCHC-type and RNA binding motif containing 1" Q8TBF4 12 42312086-42326257 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 219.4" "Cell type enhanced" "Detected in all" "Early spermatids: 889.2;Spermatocytes: 527.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (8.75e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.60e-2)" "unprognostic (9.28e-2)" "unprognostic (7.92e-3)" "prognostic unfavorable (5.33e-7)" "unprognostic (4.31e-2)" "unprognostic (1.85e-2)" "prognostic favorable (7.33e-4)" "unprognostic (3.11e-1)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.37e-6)" "unprognostic (1.39e-2)" "unprognostic (4.33e-2)" "unprognostic (5.32e-3)" "unprognostic (9.44e-2)" 46.6 52.7 110.2 31.1 117.2 37.4 43.9 114.2 219.4 30.2 99.0 48.7 35.7 35.6 66.8 40.3 38.6 38.9 61.8 106.5 119.6 51.3 57.3 27.5 44.3 123.6 116.6 41.3 62.9 43.9 40.8 33.3 126.9 42.8 30.1 39.7 44.8 40.6 128.9 34.4 35.6 30.1 121.8 31.4 46.9 89.7 114.7 43.5 45.0 91.5 41.1 41.9 30.4 125.6 94.8 69.4 76.0 99.2 67.4 102.2 74.1 77.6 86.8 59.4 57.4 60.6 110.7 59.5 152.2 74.9 83.9 58.6 46.6 78.8 87.2 162.6 96.3 94.4 55.2 58.0 96.8 103.4 81.2 68.4 87.9 58.6 98.7 140.8 81.2 153.7 91.2 120.0 85.6 61.8 146.8 129.7 83.3 233.0 91.5 82.4 140.6 128.8 97.8 52.0 79.9 75.0 105.6 72.9 109.0 84.8 175.1 84.8 76.6 86.8 104.1 82.2 76.2 118.1 120.6 222.3 129.7 366.4 41.2 79.3 33.2 65.0 35.4 42.0 45.0 68.2 47.7 43.8 55.5 60.3 39.8 46.8 22.1 51.1 44.0 67.6 82.7 40.9 110.2 117.2 114.2 219.4 106.5 119.6 123.6 116.6 126.9 121.8 114.7 125.6 58.8 60.9 67.5 13.1 54.5 45.4 82.0 108.8 56.3 43.2 90.1 129.8 152.9 82.9 83.5 57.0 25.0 143.6 53.8 44.1 217.2 139.0 889.2 113.6 76.4 68.8 48.6 35.9 13.5 200.7 141.5 67.2 35.7 88.6 53.7 39.9 61.4 114.0 111.4 38.7 14.7 82.2 73.2 76.8 69.9 159.6 112.8 61.4 71.2 9.4 103.4 122.8 82.4 15.1 27.4 156.1 52.2 100.1 59.1 82.3 62.6 249.8 113.2 51.8 72.3 63.7 129.7 527.1 185.3 53.6 41.2 87.2 56.6 85.7 75.4 90.0 ZFP91 "PZF, ZNF757" ENSG00000186660 "ZFP91 zinc finger protein, atypical E3 ubiquitin ligase" Q96JP5 11 58579063-58621550 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 243.7;Late spermatids: 179.3;Spermatocytes: 140.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA024037, CAB025417, HPA065325" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli" "CAB025417: , HPA024037: AB_1859051, HPA065325: AB_2685468" "unprognostic (6.10e-2)" "unprognostic (5.01e-2)" "unprognostic (3.33e-3)" "unprognostic (9.19e-2)" "unprognostic (1.24e-1)" "unprognostic (2.33e-1)" "unprognostic (2.33e-2)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (2.36e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (3.16e-1)" "unprognostic (1.75e-3)" "unprognostic (3.12e-2)" "unprognostic (2.61e-1)" "unprognostic (2.23e-1)" "unprognostic (2.00e-3)" 25.0 22.0 27.8 23.0 32.3 59.2 21.9 28.0 33.4 22.0 16.0 28.9 25.9 22.4 17.6 24.4 19.9 21.5 29.8 22.9 26.9 25.1 30.7 21.3 24.8 26.5 28.8 20.2 22.8 29.8 15.3 20.3 27.1 19.3 33.5 29.8 20.2 22.6 53.2 25.7 29.0 24.4 28.8 24.3 21.1 86.4 28.4 36.7 25.9 45.3 26.2 27.5 20.4 32.8 65.4 36.3 42.0 43.3 39.6 47.5 23.1 52.3 98.3 59.6 50.7 19.9 67.1 77.5 50.6 66.9 59.4 56.7 43.2 56.0 77.9 41.3 24.3 51.2 36.5 21.9 44.9 65.3 80.9 41.8 53.8 83.9 97.3 49.4 60.0 51.5 51.4 71.4 77.7 21.7 56.8 36.1 22.2 37.6 35.4 43.4 71.0 51.8 43.8 60.9 45.1 35.9 67.2 61.0 86.8 22.7 68.2 48.5 67.8 74.8 51.4 114.0 59.3 41.0 32.3 62.9 66.2 36.1 78.1 1.3 1.4 1.0 1.5 1.2 0.8 1.3 0.9 0.9 1.4 1.1 0.9 1.2 1.5 1.0 1.3 2.0 0.8 0.8 27.8 32.3 28.0 33.4 22.9 26.9 26.5 28.8 27.1 28.8 28.4 32.8 24.6 25.6 33.6 0.0 29.1 60.2 26.1 20.6 44.3 31.9 25.4 17.9 45.7 38.6 20.6 18.4 16.7 12.1 31.7 46.2 13.7 23.7 243.7 30.1 33.7 28.8 25.2 46.7 0.0 31.2 11.4 31.3 23.9 40.9 50.6 32.5 27.5 51.3 16.6 35.3 0.0 27.6 12.2 45.3 55.9 179.3 30.7 36.5 23.2 0.0 36.4 21.1 25.7 0.0 0.0 29.5 18.6 27.1 26.2 35.0 34.6 26.7 24.2 22.4 19.7 34.7 27.6 140.9 41.1 53.7 66.5 13.8 24.2 17.9 39.1 43.4 ZFR "SPG71, ZFR1" ENSG00000056097 "Zinc finger RNA binding protein" Q96KR1 5 32354350-32444740 "Predicted intracellular proteins" "Developmental protein, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016666 Supported Approved Nucleoplasm NA NA 8100 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA016666: AB_1859060" "unprognostic (7.45e-3)" "unprognostic (8.46e-2)" "unprognostic (4.07e-3)" "unprognostic (4.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (1.38e-1)" "unprognostic (1.47e-2)" "unprognostic (6.42e-2)" "unprognostic (1.58e-1)" "unprognostic (3.66e-2)" "unprognostic (1.16e-1)" "unprognostic (1.47e-2)" "unprognostic (5.46e-2)" "unprognostic (1.16e-1)" "unprognostic (2.07e-1)" 26.6 28.3 32.2 21.8 36.4 30.9 26.8 32.5 37.6 26.6 23.9 22.1 18.5 27.9 21.7 26.0 27.9 23.6 34.4 34.4 32.2 29.5 24.9 19.5 26.7 31.8 32.2 38.4 26.0 31.3 14.2 35.5 32.2 26.2 22.5 36.7 27.7 24.7 42.4 16.1 21.0 27.4 33.0 22.6 21.2 30.2 32.6 31.6 34.1 41.3 26.3 28.7 17.3 36.8 45.1 65.8 75.4 47.2 81.4 59.3 65.8 68.0 57.3 70.5 50.3 65.9 39.0 65.7 43.2 66.8 92.0 34.4 99.0 48.1 98.4 62.4 55.3 80.5 66.9 65.3 71.2 83.7 63.6 56.7 59.1 74.7 135.8 63.9 53.9 31.9 82.0 53.9 73.1 34.0 73.7 35.4 55.5 47.3 48.7 59.2 101.3 36.1 52.7 73.1 41.9 44.2 101.1 58.2 60.8 53.1 36.1 102.0 61.4 69.5 65.0 51.9 57.4 26.7 50.3 72.6 51.4 66.2 86.2 35.3 15.5 19.8 15.6 24.2 18.1 16.6 14.9 16.1 17.3 13.1 14.2 14.3 10.1 22.9 24.9 9.1 15.1 13.2 32.2 36.4 32.5 37.6 34.4 32.2 31.8 32.2 32.2 33.0 32.6 36.8 48.0 51.3 55.4 80.0 55.1 26.0 70.6 47.0 61.5 61.2 39.4 34.9 108.7 34.3 63.7 31.3 22.9 40.1 51.4 28.3 49.0 51.7 53.1 47.7 62.1 51.6 39.5 36.6 109.5 35.9 31.3 66.0 34.1 48.6 76.5 50.4 40.4 35.8 32.7 77.4 98.5 26.1 52.9 35.8 31.3 35.6 53.1 47.3 30.2 74.0 53.9 70.8 52.5 117.6 171.4 44.9 39.6 60.9 52.3 69.8 28.7 45.6 56.3 55.4 39.5 81.2 70.9 118.5 71.8 53.1 24.6 55.5 50.1 65.3 34.1 55.7 ZMAT5 "SNRNP20, ZC3H19" ENSG00000100319 "Zinc finger matrin-type 5" Q9UDW3 22 29730956-29767011 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004858 Approved Supported Nucleoplasm NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA004858: AB_1080657" "unprognostic (2.14e-1)" "unprognostic (8.03e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-2)" "unprognostic (1.02e-1)" "unprognostic (5.47e-3)" "unprognostic (6.04e-3)" "unprognostic (5.69e-2)" "unprognostic (5.75e-2)" "unprognostic (3.71e-2)" "unprognostic (2.04e-1)" "unprognostic (2.15e-2)" "unprognostic (1.03e-1)" "unprognostic (1.52e-1)" "unprognostic (2.65e-1)" "unprognostic (2.62e-1)" "unprognostic (4.10e-2)" 14.3 26.0 25.8 10.6 26.4 14.2 14.5 26.5 34.9 17.1 25.9 19.6 12.2 18.0 19.8 21.1 20.5 10.0 25.5 25.3 26.0 21.3 26.8 13.7 15.0 27.5 26.5 16.2 20.4 23.0 10.6 8.4 25.5 19.2 7.2 7.8 18.2 16.6 37.1 18.1 14.4 13.8 26.0 19.9 20.1 10.6 27.2 17.8 19.1 24.5 12.2 19.0 15.8 26.8 17.9 22.1 19.3 37.5 23.7 26.2 8.7 19.4 23.9 28.5 34.7 19.4 11.0 12.2 18.9 20.8 22.0 16.5 16.5 19.9 18.6 39.2 36.3 46.9 10.8 36.3 43.8 21.6 14.8 22.7 30.2 36.5 22.2 24.2 30.4 19.0 12.3 25.9 23.8 26.7 31.0 22.5 7.2 34.7 25.9 37.1 34.2 32.6 22.8 10.9 14.8 27.4 18.1 22.4 27.9 10.9 33.7 30.0 19.4 38.8 19.4 26.4 29.2 24.0 20.5 20.4 29.9 25.6 27.9 48.1 84.6 95.3 46.1 94.6 47.3 61.6 47.7 48.6 73.9 60.3 41.8 49.1 69.5 60.8 94.7 57.6 61.0 65.3 25.8 26.4 26.5 34.9 25.3 26.0 27.5 26.5 25.5 26.0 27.2 26.8 17.0 16.0 20.8 6.2 14.6 9.6 21.0 32.0 10.2 12.7 16.2 22.6 1.4 17.2 20.4 14.7 18.8 21.5 11.3 16.4 33.2 35.3 0.9 13.8 14.3 15.2 14.4 8.6 3.7 27.3 18.1 15.9 13.3 10.4 33.7 13.0 15.0 17.1 45.1 5.0 5.1 19.4 24.4 21.4 17.9 3.0 15.8 22.1 12.4 3.7 27.7 26.0 34.0 6.0 6.5 31.7 18.1 21.8 14.9 12.4 27.8 40.0 19.3 21.4 32.9 15.1 40.0 11.0 22.8 14.0 11.8 14.1 18.0 18.2 14.4 18.9 ZMPSTE24 "FACE-1, HGPS, PRO1, STE24, Ste24p" ENSG00000084073 "Zinc metallopeptidase STE24" O75844 1 40258041-40294180 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006988 Approved NA NA 50000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 1: Thyroid gland - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "HPA006988: AB_1080659" "unprognostic (6.32e-2)" "unprognostic (1.63e-2)" "unprognostic (3.75e-3)" "unprognostic (4.63e-2)" "unprognostic (4.16e-3)" "unprognostic (1.37e-1)" "prognostic unfavorable (5.73e-6)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (1.84e-3)" "unprognostic (4.78e-2)" "unprognostic (7.96e-2)" "unprognostic (5.06e-2)" "unprognostic (3.65e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (6.34e-4)" "unprognostic (2.71e-2)" 20.5 24.6 16.3 19.9 16.7 5.6 25.5 18.1 22.9 26.2 21.9 28.5 22.2 26.7 27.4 21.7 18.8 25.7 20.6 16.1 18.8 46.0 38.4 21.7 16.8 17.4 17.7 14.3 17.4 53.3 10.2 22.1 18.5 26.3 33.1 10.9 19.6 23.8 16.3 16.3 23.4 32.2 18.7 13.7 21.3 11.0 17.7 15.5 27.5 18.1 23.0 29.4 16.2 18.9 69.3 38.4 35.6 26.1 90.3 71.3 67.0 64.0 60.6 81.7 73.9 35.4 118.8 62.7 41.1 92.1 29.9 71.0 78.4 67.9 97.9 54.4 39.8 59.9 36.0 44.5 45.4 99.3 68.8 45.5 67.4 64.7 28.4 45.4 58.3 27.3 63.0 60.6 80.1 30.2 60.7 28.3 70.0 47.2 42.2 52.2 60.2 77.6 75.2 58.0 38.0 44.6 60.9 155.6 85.9 56.3 55.2 249.1 46.4 68.6 52.5 56.0 78.0 37.1 106.2 49.6 75.6 64.6 79.1 18.9 21.4 14.0 17.6 27.2 22.5 15.0 19.4 19.4 29.4 11.4 16.7 22.9 8.5 29.6 24.3 18.4 24.6 22.7 16.3 16.7 18.1 22.9 16.1 18.8 17.4 17.7 18.5 18.7 17.7 18.9 28.9 38.5 24.1 19.2 20.1 32.0 24.2 41.4 33.0 6.6 35.9 19.0 25.5 54.3 43.0 73.5 0.0 41.4 22.1 44.3 31.3 58.9 3.5 30.7 32.6 31.2 27.6 18.1 16.6 36.9 38.3 36.0 21.9 40.0 21.0 16.6 27.5 64.4 34.0 10.1 13.9 31.0 54.9 33.9 24.5 2.2 28.6 28.6 24.9 11.2 30.5 29.3 19.6 17.6 20.2 44.0 29.3 32.7 31.1 37.7 31.7 42.6 64.2 7.7 0.0 26.8 41.2 7.8 6.4 31.5 27.1 39.0 23.1 28.9 35.6 24.5 ZMYND11 BS69 ENSG00000015171 "Zinc finger MYND-type containing 11" Q15326 10 134465-254637 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015816 Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA015816: AB_1845427" "unprognostic (1.96e-1)" "unprognostic (1.66e-1)" "unprognostic (3.00e-1)" "unprognostic (1.12e-1)" "unprognostic (9.12e-2)" "unprognostic (2.33e-2)" "unprognostic (5.49e-2)" "unprognostic (1.52e-2)" "unprognostic (1.80e-2)" "unprognostic (3.73e-2)" "unprognostic (4.47e-3)" "unprognostic (6.35e-2)" "prognostic favorable (4.76e-7)" "unprognostic (1.25e-1)" "unprognostic (2.40e-1)" "unprognostic (9.04e-2)" "unprognostic (1.42e-1)" 41.7 37.1 50.7 26.3 58.8 11.3 45.8 60.0 64.6 47.4 38.5 54.8 29.9 55.0 46.6 42.8 39.8 35.6 58.0 50.7 54.8 51.1 34.9 39.0 26.3 54.1 52.8 55.3 46.4 99.7 27.7 34.8 54.8 52.8 33.8 43.2 46.1 56.0 58.1 33.1 30.9 50.9 52.4 32.7 39.2 33.1 54.1 23.8 88.0 64.7 24.8 46.7 31.1 59.1 64.0 64.6 53.8 42.9 57.3 55.0 33.3 63.0 35.8 43.7 40.5 39.2 62.3 0.1 19.8 78.4 13.8 38.3 28.9 44.2 55.8 25.1 25.1 71.8 33.4 42.3 64.6 19.5 38.8 38.4 60.6 42.3 38.3 56.8 55.6 32.8 19.5 44.7 76.0 75.4 29.3 27.3 17.4 69.3 10.7 28.4 34.4 34.5 58.0 72.7 24.3 44.3 72.3 83.3 34.1 29.4 74.9 37.8 72.2 43.4 15.8 89.2 48.8 37.0 48.4 4.6 44.2 36.1 30.3 15.6 2.3 19.5 11.9 3.5 10.4 5.2 8.3 11.9 3.8 3.1 9.2 9.1 1.0 14.7 1.7 4.5 8.9 5.0 50.7 58.8 60.0 64.6 50.7 54.8 54.1 52.8 54.8 52.4 54.1 59.1 51.2 60.9 51.4 90.8 25.3 25.9 27.0 17.5 34.1 37.5 46.3 33.8 103.0 31.5 31.9 33.1 12.5 15.2 39.4 14.6 50.9 29.3 28.6 27.0 50.3 45.7 25.9 25.0 110.8 31.8 4.6 45.7 27.5 37.1 46.2 42.1 35.3 28.1 14.4 20.2 118.0 26.2 16.2 25.1 14.9 27.1 39.1 21.7 24.9 94.6 13.9 62.5 34.0 128.2 131.5 28.1 14.5 56.1 31.1 44.1 19.1 41.9 23.7 22.0 13.1 56.9 49.8 26.8 25.6 32.2 27.8 12.4 32.6 28.5 22.1 29.8 ZNF362 "FLJ25476, lin-29, RN" ENSG00000160094 "Zinc finger protein 362" Q5T0B9 1 33256492-33300719 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059239 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA059239: AB_2683955" "unprognostic (8.31e-3)" "unprognostic (2.61e-1)" "unprognostic (2.23e-2)" "unprognostic (6.90e-3)" "unprognostic (1.08e-1)" "unprognostic (2.34e-2)" "unprognostic (4.02e-3)" "unprognostic (2.02e-2)" "unprognostic (7.74e-2)" "unprognostic (1.82e-1)" "unprognostic (9.25e-2)" "unprognostic (1.52e-1)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (2.67e-1)" "unprognostic (5.83e-2)" "unprognostic (2.66e-1)" 15.7 12.0 18.4 8.5 17.2 6.7 15.5 17.2 23.1 19.5 8.5 18.9 7.3 22.0 10.2 12.6 16.3 9.1 20.2 16.9 15.6 15.4 8.9 12.6 9.4 18.3 15.4 17.0 13.5 11.9 17.7 11.3 14.3 20.1 5.5 6.3 16.4 13.3 19.7 17.7 11.6 11.7 12.7 16.2 13.7 7.6 18.0 12.2 16.3 11.3 6.7 18.6 15.0 15.8 6.3 10.3 43.7 17.4 11.3 7.9 27.8 8.6 10.3 10.7 11.3 10.6 21.2 3.0 17.1 11.2 3.3 20.6 10.2 5.0 4.5 18.0 7.5 16.1 6.1 13.2 10.1 7.3 12.3 16.9 12.2 4.7 4.1 10.8 14.8 21.2 1.6 5.5 8.3 15.7 23.9 12.9 23.9 3.9 8.4 39.4 10.4 1.5 8.6 10.2 15.4 46.4 24.8 7.8 39.9 18.5 7.7 19.9 21.0 6.5 8.2 15.2 5.6 15.8 15.3 3.4 5.1 6.7 19.4 1.9 1.9 2.6 1.8 1.7 1.3 1.1 1.3 1.6 1.4 2.9 1.2 1.2 1.4 1.7 2.0 3.5 1.1 1.3 18.4 17.2 17.2 23.1 16.9 15.6 18.3 15.4 14.3 12.7 18.0 15.8 15.6 9.6 12.4 13.1 9.2 10.1 4.7 6.2 20.5 12.8 11.0 11.2 25.5 5.7 7.9 11.0 0.0 11.7 16.6 2.6 1.9 6.6 2.5 5.2 12.0 13.9 1.8 3.4 14.3 7.3 5.9 11.8 3.6 7.6 10.1 15.3 18.2 6.9 10.2 8.4 17.7 4.4 6.1 13.9 5.0 8.0 13.7 11.2 8.8 19.7 9.9 9.2 10.3 26.7 14.3 4.3 10.7 21.4 7.5 1.9 7.3 11.4 2.4 4.9 6.6 12.4 16.7 1.2 5.0 11.4 9.5 3.6 10.6 7.7 6.1 2.9 ZNF607 "FLJ14802, MGC13071" ENSG00000198182 "Zinc finger protein 607" Q96SK3 19 37696371-37719761 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 33.0;Late spermatids: 26.7;Smooth muscle cells: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA049465, HPA055018" Uncertain Approved Nucleoplasm NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA049465: AB_2680778, HPA055018: AB_2682674" "unprognostic (6.70e-2)" "unprognostic (8.00e-2)" "unprognostic (1.77e-3)" "unprognostic (2.69e-3)" "unprognostic (1.58e-1)" "unprognostic (9.23e-2)" "unprognostic (9.86e-3)" "unprognostic (2.15e-1)" "unprognostic (4.86e-2)" "unprognostic (1.95e-1)" "unprognostic (1.80e-3)" "unprognostic (1.68e-1)" "unprognostic (6.43e-3)" "unprognostic (3.86e-1)" "unprognostic (4.30e-2)" "unprognostic (5.03e-2)" "prognostic favorable (5.23e-5)" 1.8 2.9 4.6 1.5 5.4 0.5 3.3 5.5 4.8 3.3 4.2 3.1 1.7 3.4 3.3 3.1 4.6 1.8 2.9 4.1 4.6 3.3 0.8 2.1 2.7 6.4 4.6 5.1 2.8 5.3 5.5 2.7 4.9 3.3 2.0 5.0 2.3 2.5 2.0 3.5 2.7 2.3 4.7 3.1 2.4 9.0 5.1 2.8 4.0 2.0 3.3 3.0 3.1 6.5 5.1 5.3 8.0 8.4 4.3 4.9 5.6 3.7 3.6 3.3 5.9 8.0 2.8 7.1 5.2 3.9 4.4 2.4 7.9 2.8 5.0 3.7 8.1 3.5 4.6 4.4 3.5 0.1 2.1 3.2 5.3 4.1 3.8 4.8 1.7 4.7 7.3 0.0 3.7 4.4 7.1 3.9 9.4 3.6 2.1 3.2 12.3 1.9 3.5 6.6 2.3 7.0 0.2 2.1 0.6 5.8 5.7 0.6 0.4 2.4 1.7 2.9 4.2 6.9 8.0 9.8 0.0 0.0 3.2 0.0 0.2 1.6 1.3 0.2 0.9 3.0 2.2 2.8 0.8 2.0 1.9 2.3 0.0 2.4 0.3 1.6 0.8 0.8 4.6 5.4 5.5 4.8 4.1 4.6 6.4 4.6 4.9 4.7 5.1 6.5 1.3 3.2 0.5 4.9 3.0 1.3 0.8 1.5 2.8 2.7 2.1 2.5 4.1 2.8 1.9 1.8 2.1 2.5 1.1 1.2 0.0 1.7 33.0 3.2 1.5 1.3 0.0 0.4 5.5 1.2 2.3 1.6 2.6 1.6 0.0 3.2 1.8 0.2 1.4 1.7 7.1 1.9 0.0 0.6 0.4 26.7 0.9 0.7 3.6 1.0 0.6 1.2 2.1 3.0 10.6 0.7 0.5 1.9 0.6 1.2 1.0 1.2 7.2 1.5 0.0 1.1 13.9 5.4 5.2 2.9 1.1 0.8 1.4 1.6 1.5 0.9 ZNF710 "DKFZp547K1113, FLJ00306, FLJ37393" ENSG00000140548 "Zinc finger protein 710" Q8N1W2 15 90001324-90082206 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 44.2" "Cell type enhanced" "Detected in many" "Astrocytes: 38.8;Microglial cells: 149.9;Oligodendrocytes: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 5.7" "Group enriched" "Detected in many" 6 "dendritic cells: 1.4;granulocytes: 1.9;monocytes: 5.7" "Cell line enhanced" "Detected in all" "SK-BR-3: 44.8" "Low region specificity" "Detected in all" "HPA030226, HPA030227, HPA030228" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA030226: AB_2673384, HPA030227: AB_10599855, HPA030228: AB_10601899" "unprognostic (6.24e-2)" "unprognostic (7.07e-2)" "unprognostic (1.49e-2)" "unprognostic (2.40e-1)" "unprognostic (2.32e-1)" "unprognostic (1.36e-2)" "unprognostic (4.34e-2)" "unprognostic (8.45e-2)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" "unprognostic (9.86e-2)" "unprognostic (1.57e-1)" "unprognostic (2.91e-3)" "unprognostic (1.03e-2)" "unprognostic (3.24e-2)" "unprognostic (1.65e-2)" "unprognostic (8.65e-2)" 3.6 4.3 12.0 14.7 13.0 8.7 5.4 6.4 11.2 6.3 3.1 8.3 9.1 5.3 5.0 17.1 5.2 7.0 10.0 6.9 8.8 5.7 5.3 9.8 10.0 12.2 13.6 4.8 44.2 3.3 4.5 5.7 12.9 7.5 6.9 1.2 9.6 4.3 33.4 12.6 8.0 3.4 10.4 14.2 10.2 1.7 12.4 5.6 6.2 1.5 6.5 7.7 9.2 11.5 9.2 10.7 20.1 7.6 2.7 4.0 10.5 9.4 8.8 6.8 8.6 7.7 8.3 9.3 4.3 9.1 6.4 6.2 5.1 13.5 3.8 6.0 9.4 17.1 4.6 13.1 5.5 5.0 25.6 6.6 7.2 14.6 7.9 3.2 11.8 10.0 5.8 6.2 2.6 23.7 11.1 13.9 15.8 11.3 6.9 13.5 4.5 10.2 2.7 11.4 18.3 12.3 12.5 44.8 6.4 5.2 9.6 17.2 17.1 13.9 6.8 4.2 7.4 5.0 2.7 9.0 10.6 14.6 7.4 0.0 1.6 1.2 0.2 3.5 0.2 0.1 0.1 0.2 1.2 0.1 0.4 0.4 1.9 0.2 5.7 1.4 0.5 0.7 12.0 13.0 6.4 11.2 6.9 8.8 12.2 13.6 12.9 10.4 12.4 11.5 1.7 3.2 8.2 38.8 2.7 5.4 4.7 2.8 1.8 1.4 7.1 3.6 12.1 4.3 6.3 11.0 2.1 2.3 6.8 7.7 0.0 3.6 0.8 4.0 4.1 4.3 4.8 2.5 10.2 6.1 3.0 3.1 7.1 6.2 1.3 2.1 5.7 1.6 11.6 3.3 12.0 8.1 0.0 15.8 33.5 5.5 2.5 15.7 1.8 149.9 13.3 1.4 2.1 22.1 36.4 10.1 11.5 3.0 3.8 8.5 2.3 0.8 3.6 0.9 6.6 1.6 3.0 0.3 2.5 4.3 7.5 2.3 2.5 2.0 6.5 13.7 ZNF90 HTF9 ENSG00000213988 "Zinc finger protein 90" Q03938 19 20077994-20127076 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 217.1;Langerhans cells: 329.2;Smooth muscle cells: 451.1;Suprabasal keratinocytes: 280.3" "Cancer enriched" "Detected in many" 4 "testis cancer: 10.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 9.5;NB-4: 7.9;NTERA-2: 17.0;SuSa: 10.5;U-2197: 7.0" HPA003227 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Golgi apparatus" "HPA003227: AB_1859471" "unprognostic (4.52e-2)" "unprognostic (2.64e-3)" "unprognostic (3.93e-1)" "unprognostic (2.45e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-2)" "unprognostic (7.34e-3)" "unprognostic (4.95e-1)" "unprognostic (4.44e-3)" "unprognostic (2.28e-1)" "unprognostic (1.09e-1)" "unprognostic (1.18e-4)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (9.10e-2)" "unprognostic (2.60e-2)" 0.3 0.2 0.1 0.6 0.3 0.6 0.5 1.0 0.2 0.8 0.2 0.5 0.2 0.9 0.6 0.4 0.8 0.3 0.3 0.1 0.2 0.5 0.1 0.7 1.2 0.3 0.2 1.5 0.9 1.8 0.3 1.2 0.3 0.6 0.7 0.0 0.3 1.4 0.2 1.1 0.6 0.6 0.1 0.5 0.8 0.6 0.3 0.8 1.9 0.0 0.8 1.0 0.7 0.4 0.0 0.0 3.7 9.5 0.0 0.0 0.0 0.9 0.3 3.3 4.0 3.2 2.3 1.3 1.7 0.6 2.5 1.1 0.0 0.5 5.7 0.0 0.9 0.0 0.0 0.5 0.3 0.0 0.0 0.3 0.0 3.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 1.8 7.9 17.0 0.0 0.0 0.0 3.1 0.4 2.3 3.3 0.0 3.9 0.0 1.4 0.2 10.5 1.8 0.0 0.0 1.0 0.0 7.0 3.7 0.0 1.5 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.2 0.1 0.2 0.3 0.2 0.3 0.1 0.3 0.4 2.2 6.4 8.4 1.0 31.7 217.1 112.5 32.7 2.8 0.6 7.8 6.6 1.9 50.1 16.7 7.3 2.1 87.5 25.1 4.8 17.6 2.3 8.2 1.9 4.9 28.8 8.5 26.7 0.5 2.0 99.1 27.6 1.5 4.5 1.3 9.3 54.3 57.1 47.8 0.0 0.7 16.9 14.2 107.1 329.2 24.2 60.9 14.9 124.5 5.6 34.6 2.2 44.3 1.5 2.9 1.2 12.3 34.6 1.8 87.8 8.4 14.0 8.6 2.5 19.7 45.2 451.1 8.6 16.7 1.9 280.3 81.5 40.1 16.0 19.0 66.4